+D GENES KO #

  KEGG Orthology (KO) - Spirochaeta africana

% ! A09100 Metabolism B B 09101 Carbohydrate metabolism C 00010 Glycolysis / Gluconeogenesis [PATH:sfc00010] D Spiaf_1278 glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D Spiaf_2818 transcriptional regulator/sugar kinase K25026 glk; glucokinase [EC:2.7.1.2] D Spiaf_0190 glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Spiaf_2436 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Spiaf_0482 6-phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] D Spiaf_1173 diphosphate--fructose-6-phosphate 1-phosphotransferase K00895 pfp; diphosphate-dependent phosphofructokinase [EC:2.7.1.90] D Spiaf_0622 fructose-bisphosphate aldolase, class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D Spiaf_1631 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D Spiaf_1633 glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D Spiaf_1632 3-phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D Spiaf_1156 fructose-2,6-bisphosphatase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D Spiaf_0526 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Spiaf_0670 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Spiaf_2001 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Spiaf_0166 phosphoenolpyruvate synthase/pyruvate phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] D Spiaf_2157 phosphoenolpyruvate synthase/pyruvate phosphate dikinase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D Spiaf_1803 pyruvate dehydrogenase E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D Spiaf_1802 pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D Spiaf_1801 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Spiaf_1800 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_0773 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_0538 pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] D Spiaf_2292 L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D Spiaf_2451 alcohol dehydrogenase, class IV K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D Spiaf_2546 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Spiaf_0466 galactose mutarotase-like enzyme K01785 galM; aldose 1-epimerase [EC:5.1.3.3] D Spiaf_0830 phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] C 00020 Citrate cycle (TCA cycle) [PATH:sfc00020] D Spiaf_2703 citrate synthase K01647 CS; citrate synthase [EC:2.3.3.1] D Spiaf_1738 aconitate hydratase 1 K01681 ACO; aconitate hydratase [EC:4.2.1.3] D Spiaf_1226 isocitrate dehydrogenase, NADP-dependent, monomeric type K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42] D Spiaf_1800 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_0773 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_0131 succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D Spiaf_0130 succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D Spiaf_1812 fumarase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2] D Spiaf_1803 pyruvate dehydrogenase E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D Spiaf_1802 pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D Spiaf_1801 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Spiaf_0538 pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] C 00030 Pentose phosphate pathway [PATH:sfc00030] D Spiaf_0190 glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Spiaf_0198 glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D Spiaf_0295 6-phosphogluconolactonase K01057 PGLS; 6-phosphogluconolactonase [EC:3.1.1.31] D Spiaf_1268 6-phosphogluconate dehydrogenase, decarboxylating K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] D Spiaf_1526 ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D Spiaf_2756 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D Spiaf_0126 transketolase, beta subunit K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D Spiaf_0127 transketolase, alpha subunit K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D Spiaf_0457 ribose 5-phosphate isomerase K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D Spiaf_0128 sugar-phosphate isomerase, RpiB/LacA/LacB family K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6] D Spiaf_1191 deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4] D Spiaf_0830 phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D Spiaf_1522 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D Spiaf_1852 Entner-Doudoroff aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42] D Spiaf_2196 carbohydrate kinase, thermoresistant glucokinase family K00851 idnK; gluconokinase [EC:2.7.1.12] D Spiaf_0622 fructose-bisphosphate aldolase, class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D Spiaf_2436 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Spiaf_0482 6-phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] D Spiaf_1173 diphosphate--fructose-6-phosphate 1-phosphotransferase K00895 pfp; diphosphate-dependent phosphofructokinase [EC:2.7.1.90] C 00040 Pentose and glucuronate interconversions [PATH:sfc00040] D Spiaf_0064 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Spiaf_0260 UDP-glucose pyrophosphorylase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Spiaf_1526 ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D Spiaf_0416 pentulose/hexulose kinase K00854 xylB; xylulokinase [EC:2.7.1.17] D Spiaf_2332 pentulose/hexulose kinase K00854 xylB; xylulokinase [EC:2.7.1.17] D Spiaf_2005 pentulose/hexulose kinase K00854 xylB; xylulokinase [EC:2.7.1.17] D Spiaf_2331 xylose isomerase K01805 xylA; xylose isomerase [EC:5.3.1.5] D Spiaf_0415 theronine dehydrogenase-like Zn-dependent dehydrogenase K05351 E1.1.1.9; D-xylulose reductase [EC:1.1.1.9] C 00051 Fructose and mannose metabolism [PATH:sfc00051] D Spiaf_1483 transcriptional regulator/sugar kinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D Spiaf_1179 mannose-6-phosphate isomerase, class I K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] D Spiaf_0677 mannose-1-phosphate guanylyltransferase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8] D Spiaf_2436 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Spiaf_0482 6-phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] D Spiaf_1173 diphosphate--fructose-6-phosphate 1-phosphotransferase K00895 pfp; diphosphate-dependent phosphofructokinase [EC:2.7.1.90] D Spiaf_0684 1-phosphofructokinase K00882 fruK; 1-phosphofructokinase [EC:2.7.1.56] D Spiaf_2331 xylose isomerase K01805 xylA; xylose isomerase [EC:5.3.1.5] D Spiaf_0622 fructose-bisphosphate aldolase, class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D Spiaf_1631 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D Spiaf_0128 sugar-phosphate isomerase, RpiB/LacA/LacB family K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6] D Spiaf_0685 PTS system, fructose-specific, IIB component/PTS system, fructose subfamily, IIC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] C 00052 Galactose metabolism [PATH:sfc00052] D Spiaf_0466 galactose mutarotase-like enzyme K01785 galM; aldose 1-epimerase [EC:5.1.3.3] D Spiaf_2395 galactokinase K00849 galK; galactokinase [EC:2.7.1.6] D Spiaf_1934 galactokinase K00849 galK; galactokinase [EC:2.7.1.6] D Spiaf_2394 UDP-glucose-4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Spiaf_0260 UDP-glucose pyrophosphorylase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Spiaf_0830 phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D Spiaf_1278 glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D Spiaf_2818 transcriptional regulator/sugar kinase K25026 glk; glucokinase [EC:2.7.1.2] D Spiaf_2392 beta-galactosidase K12308 bgaB; beta-galactosidase [EC:3.2.1.23] D Spiaf_0279 alpha-galactosidase K07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22] D Spiaf_2436 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Spiaf_0482 6-phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] D Spiaf_1283 beta-fructosidase, levanase/invertase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26] D Spiaf_1105 glycosidase K01187 malZ; alpha-glucosidase [EC:3.2.1.20] D Spiaf_0775 glycosidase K01187 malZ; alpha-glucosidase [EC:3.2.1.20] D Spiaf_2580 glycosidase K01182 IMA; oligo-1,6-glucosidase [EC:3.2.1.10] D Spiaf_2481 glycosidase K01182 IMA; oligo-1,6-glucosidase [EC:3.2.1.10] C 00053 Ascorbate and aldarate metabolism [PATH:sfc00053] D Spiaf_0064 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Spiaf_0243 FAD/FMN-dependent dehydrogenase K00103 GULO; L-gulonolactone oxidase [EC:1.1.3.8] D Spiaf_0061 nucleoside-diphosphate-sugar epimerase K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6] D Spiaf_2546 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] C 00500 Starch and sucrose metabolism [PATH:sfc00500] D Spiaf_1283 beta-fructosidase, levanase/invertase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26] D Spiaf_1105 glycosidase K01187 malZ; alpha-glucosidase [EC:3.2.1.20] D Spiaf_0775 glycosidase K01187 malZ; alpha-glucosidase [EC:3.2.1.20] D Spiaf_0707 glycosidase K05341 E2.4.1.4; amylosucrase [EC:2.4.1.4] D Spiaf_0260 UDP-glucose pyrophosphorylase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Spiaf_0288 beta-glucosidase-like glycosyl hydrolase K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spiaf_0357 beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase K05350 bglB; beta-glucosidase [EC:3.2.1.21] D Spiaf_2170 beta-galactosidase K05350 bglB; beta-glucosidase [EC:3.2.1.21] D Spiaf_0702 hypothetical protein K00702 E2.4.1.20; cellobiose phosphorylase [EC:2.4.1.20] D Spiaf_0787 ADP-glucose pyrophosphorylase K00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27] D Spiaf_0790 glycogen/starch synthase, ADP-glucose type K00703 glgA; starch synthase [EC:2.4.1.21] D Spiaf_0522 glycosyltransferase K00693 GYS; glycogen synthase [EC:2.4.1.11] D Spiaf_0039 glycosyltransferase K16150 K16150; glycogen synthase [EC:2.4.1.11] D Spiaf_2125 hypothetical protein K16149 K16149; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18] D Spiaf_0693 glycogen/starch/alpha-glucan phosphorylase K00688 PYG; glycogen phosphorylase [EC:2.4.1.1] D Spiaf_1174 pullulanase-like glycosidase possibly secreted by type II secretory pathway K01200 pulA; pullulanase [EC:3.2.1.41] D Spiaf_2348 pullulanase-like glycosidase possibly secreted by type II secretory pathway K01200 pulA; pullulanase [EC:3.2.1.41] D Spiaf_0120 glycosidase K01176 AMY; alpha-amylase [EC:3.2.1.1] D Spiaf_2351 glycosidase K01176 AMY; alpha-amylase [EC:3.2.1.1] D Spiaf_2357 glycosidase K01176 AMY; alpha-amylase [EC:3.2.1.1] D Spiaf_0893 glycosidase K01176 AMY; alpha-amylase [EC:3.2.1.1] D Spiaf_0690 glycosidase K01176 AMY; alpha-amylase [EC:3.2.1.1] D Spiaf_2521 glycosidase K01176 AMY; alpha-amylase [EC:3.2.1.1] D Spiaf_2522 glycosidase K01176 AMY; alpha-amylase [EC:3.2.1.1] D Spiaf_0475 glycosidase K01176 AMY; alpha-amylase [EC:3.2.1.1] D Spiaf_2269 glycosidase K01176 AMY; alpha-amylase [EC:3.2.1.1] D Spiaf_0689 trehalose synthase K05343 treS; maltose alpha-D-glucosyltransferase / alpha-amylase [EC:5.4.99.16 3.2.1.1] D Spiaf_0994 glycosidase K01208 cd; cyclomaltodextrinase / maltogenic alpha-amylase / neopullulanase [EC:3.2.1.54 3.2.1.133 3.2.1.135] D Spiaf_0110 glycosidase K01208 cd; cyclomaltodextrinase / maltogenic alpha-amylase / neopullulanase [EC:3.2.1.54 3.2.1.133 3.2.1.135] D Spiaf_2580 glycosidase K01182 IMA; oligo-1,6-glucosidase [EC:3.2.1.10] D Spiaf_2481 glycosidase K01182 IMA; oligo-1,6-glucosidase [EC:3.2.1.10] D Spiaf_0101 4-alpha-glucanotransferase K00705 malQ; 4-alpha-glucanotransferase [EC:2.4.1.25] D Spiaf_0688 4-alpha-glucanotransferase K00705 malQ; 4-alpha-glucanotransferase [EC:2.4.1.25] D Spiaf_1053 hypothetical protein K22451 jgt; 4-alpha-glucanotransferase [EC:2.4.1.25] D Spiaf_1196 beta-phosphoglucomutase K01838 pgmB; beta-phosphoglucomutase [EC:5.4.2.6] D Spiaf_0244 haloacid dehalogenase superfamily protein, subfamily IA, variant 3 with third motif having DD or ED K01838 pgmB; beta-phosphoglucomutase [EC:5.4.2.6] D Spiaf_2605 glycogen debranching enzyme GlgX K01214 ISA; isoamylase [EC:3.2.1.68] D Spiaf_2040 glycogen debranching enzyme GlgX K01214 ISA; isoamylase [EC:3.2.1.68] D Spiaf_2048 pullulanase-like glycosidase possibly secreted by type II secretory pathway K01214 ISA; isoamylase [EC:3.2.1.68] D Spiaf_0303 malto-oligosyltrehalose synthase K06044 treY; (1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase [EC:5.4.99.15] D Spiaf_0304 malto-oligosyltrehalose trehalohydrolase K01236 treZ; maltooligosyltrehalose trehalohydrolase [EC:3.2.1.141] D Spiaf_1194 UDP-forming alpha,alpha-trehalose-phosphate synthase K16055 TPS; trehalose 6-phosphate synthase/phosphatase [EC:2.4.1.15 3.1.3.12] D Spiaf_2492 trehalose/maltose hydrolase or phosphorylase K05342 treP; alpha,alpha-trehalose phosphorylase [EC:2.4.1.64] D Spiaf_0830 phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D Spiaf_1278 glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D Spiaf_2818 transcriptional regulator/sugar kinase K25026 glk; glucokinase [EC:2.7.1.2] D Spiaf_0190 glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Spiaf_1483 transcriptional regulator/sugar kinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] C 00520 Amino sugar and nucleotide sugar metabolism [PATH:sfc00520] D Spiaf_0792 beta-glucosidase-like glycosyl hydrolase K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52] D Spiaf_1045 beta-glucosidase-like glycosyl hydrolase K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52] D Spiaf_1483 transcriptional regulator/sugar kinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D Spiaf_2543 glucosamine--fructose-6-phosphate aminotransferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Spiaf_2765 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D Spiaf_2490 UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D Spiaf_1393 beta-xylosidase K01198 xynB; xylan 1,4-beta-xylosidase [EC:3.2.1.37] D Spiaf_1278 glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D Spiaf_2818 transcriptional regulator/sugar kinase K25026 glk; glucokinase [EC:2.7.1.2] D Spiaf_0830 phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D Spiaf_0260 UDP-glucose pyrophosphorylase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Spiaf_0064 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Spiaf_2395 galactokinase K00849 galK; galactokinase [EC:2.7.1.6] D Spiaf_1934 galactokinase K00849 galK; galactokinase [EC:2.7.1.6] D Spiaf_2394 UDP-glucose-4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Spiaf_0061 nucleoside-diphosphate-sugar epimerase K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6] D Spiaf_0190 glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Spiaf_1179 mannose-6-phosphate isomerase, class I K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] D Spiaf_0677 mannose-1-phosphate guanylyltransferase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8] D Spiaf_0787 ADP-glucose pyrophosphorylase K00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27] C 00620 Pyruvate metabolism [PATH:sfc00620] D Spiaf_0538 pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] D Spiaf_1803 pyruvate dehydrogenase E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D Spiaf_1802 pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D Spiaf_1801 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Spiaf_1800 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_0773 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_2421 formate acetyltransferase 1 K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54] D Spiaf_2451 alcohol dehydrogenase, class IV K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D Spiaf_2497 acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D Spiaf_1162 acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D Spiaf_2203 phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D Spiaf_2001 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Spiaf_2211 acetyl-CoA carboxylase, carboxyl transferase, alpha subunit K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D Spiaf_2214 acetyl-CoA carboxylase, biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D Spiaf_2213 acetyl/propionyl-CoA carboxylase, alpha subunit K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D Spiaf_2212 acetyl-CoA carboxylase, carboxyl transferase, beta subunit K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D Spiaf_1269 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] D Spiaf_2546 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Spiaf_2292 L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D Spiaf_2059 Zn-dependent hydrolase, glyoxylase K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6] D Spiaf_1655 hypothetical protein K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6] D Spiaf_0825 malic enzyme K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] D Spiaf_1812 fumarase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2] D Spiaf_0824 phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D Spiaf_0914 hypothetical protein K20370 PEPCK; phosphoenolpyruvate carboxykinase (diphosphate) [EC:4.1.1.38] D Spiaf_0166 phosphoenolpyruvate synthase/pyruvate phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] D Spiaf_2157 phosphoenolpyruvate synthase/pyruvate phosphate dikinase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D Spiaf_2588 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Spiaf_1894 2-isopropylmalate synthase/homocitrate synthase family protein K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] D Spiaf_2397 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] C 00630 Glyoxylate and dicarboxylate metabolism [PATH:sfc00630] D Spiaf_2703 citrate synthase K01647 CS; citrate synthase [EC:2.3.3.1] D Spiaf_1738 aconitate hydratase 1 K01681 ACO; aconitate hydratase [EC:4.2.1.3] D Spiaf_2588 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Spiaf_2262 haloacid dehalogenase superfamily enzyme, subfamily IA K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18] D Spiaf_2268 putative phosphatase K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18] D Spiaf_2416 putative phosphatase K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18] D Spiaf_0307 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Spiaf_1199 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Spiaf_2484 glycine/serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Spiaf_0481 glycine dehydrogenase, decarboxylating K00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2] D Spiaf_1800 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_0773 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_0009 glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein D Spiaf_1852 Entner-Doudoroff aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42] C 00640 Propanoate metabolism [PATH:sfc00640] D Spiaf_2497 acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D Spiaf_1162 acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D Spiaf_2203 phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D Spiaf_2502 pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit K11381 bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4] D Spiaf_1800 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_0773 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_2421 formate acetyltransferase 1 K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54] D Spiaf_2211 acetyl-CoA carboxylase, carboxyl transferase, alpha subunit K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D Spiaf_2214 acetyl-CoA carboxylase, biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D Spiaf_2213 acetyl/propionyl-CoA carboxylase, alpha subunit K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D Spiaf_2212 acetyl-CoA carboxylase, carboxyl transferase, beta subunit K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D Spiaf_0130 succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D Spiaf_0131 succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D Spiaf_2292 L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] C 00650 Butanoate metabolism [PATH:sfc00650] D Spiaf_2588 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Spiaf_1423 putative paraquat-inducible protein B K00209 fabV; enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44] D Spiaf_2451 alcohol dehydrogenase, class IV K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D Spiaf_0177 NAD-dependent aldehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Spiaf_2421 formate acetyltransferase 1 K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54] D Spiaf_0538 pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] D Spiaf_0377 3-hydroxy-3-methylglutaryl CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D Spiaf_1663 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Spiaf_1664 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] C 00660 C5-Branched dibasic acid metabolism [PATH:sfc00660] D Spiaf_1663 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Spiaf_1664 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D Spiaf_0130 succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D Spiaf_0131 succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D Spiaf_2344 3-isopropylmalate dehydratase, large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D Spiaf_2345 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D Spiaf_2757 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] C 00562 Inositol phosphate metabolism [PATH:sfc00562] D Spiaf_0242 inositol monophosphatase/fructose-1,6-bisphosphatase family protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D Spiaf_1631 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] B B 09102 Energy metabolism C 00190 Oxidative phosphorylation [PATH:sfc00190] D Spiaf_2405 NADH:ubiquinone oxidoreductase 24 kD subunit K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2] D Spiaf_1752 NADH:ubiquinone oxidoreductase 24 kD subunit K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2] D Spiaf_2408 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2] D Spiaf_1751 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2] D Spiaf_1110 formate hydrogenlyase subunit 3/multisubunit Na+/H+ antiporter, MnhD subunit K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2] D Spiaf_0080 NADH dehydrogenase, FAD-containing subunit K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9] D Spiaf_1645 archaeal/vacuolar-type H+-ATPase subunit A K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1] D Spiaf_1644 archaeal/vacuolar-type H+-ATPase subunit B K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B D Spiaf_1643 H(+)-transporting ATP synthase, vacuolar type, subunit D K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D D Spiaf_1647 hypothetical protein K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E D Spiaf_1642 archaeal/vacuolar-type H+-ATPase subunit I K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I D Spiaf_1641 ATP synthase subunit C K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K D Spiaf_2816 polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] C 00195 Photosynthesis C 00196 Photosynthesis - antenna proteins C 00710 Carbon fixation in photosynthetic organisms C 00720 Carbon fixation pathways in prokaryotes C 00680 Methane metabolism [PATH:sfc00680] D Spiaf_2484 glycine/serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Spiaf_0670 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Spiaf_0824 phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D Spiaf_0622 fructose-bisphosphate aldolase, class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D Spiaf_2436 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Spiaf_0482 6-phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] D Spiaf_2497 acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D Spiaf_1162 acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D Spiaf_2203 phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D Spiaf_2157 phosphoenolpyruvate synthase/pyruvate phosphate dikinase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D Spiaf_1156 fructose-2,6-bisphosphatase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D Spiaf_0526 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Spiaf_2706 phosphoglycerate dehydrogenase-like oxidoreductase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Spiaf_2701 phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D Spiaf_1783 phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] D Spiaf_2654 phosphoserine phosphatase/homoserine phosphotransferase K02203 thrH; phosphoserine / homoserine phosphotransferase [EC:3.1.3.3 2.7.1.39] D Spiaf_2755 fructose-2,6-bisphosphatase K22305 psp; phosphoserine phosphatase [EC:3.1.3.3] D Spiaf_0383 alpha-L-glutamate ligase, RimK family K14940 cofF; gamma-F420-2:alpha-L-glutamate ligase [EC:6.3.2.32] C 00910 Nitrogen metabolism [PATH:sfc00910] D Spiaf_2281 hydroxylamine reductase K05601 hcp; hydroxylamine reductase [EC:1.7.99.1] D Spiaf_2158 glutamate dehydrogenase/leucine dehydrogenase K00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] D Spiaf_0307 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Spiaf_1199 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Spiaf_1890 glutamate synthase family protein K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] D Spiaf_1889 NADH/NADPH-dependent glutamate synthase small subunit K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] D Spiaf_2825 NADPH-dependent glutamate synthase, homotetrameric K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] D Spiaf_2068 carbonic anhydrase K01673 cynT; carbonic anhydrase [EC:4.2.1.1] C 00920 Sulfur metabolism [PATH:sfc00920] D Spiaf_2444 sulfate/thiosulfate-binding protein K02048 cysP; sulfate/thiosulfate transport system substrate-binding protein D Spiaf_2443 sulfate ABC transporter, permease protein CysT K02046 cysU; sulfate/thiosulfate transport system permease protein D Spiaf_2442 sulfate ABC transporter, permease protein K02047 cysW; sulfate/thiosulfate transport system permease protein D Spiaf_2441 sulfate ABC transporter, ATP-binding protein K02045 cysA; sulfate/thiosulfate transport system ATP-binding protein [EC:7.3.2.3] D Spiaf_0967 inositol monophosphatase/fructose-1,6-bisphosphatase family protein K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7] D Spiaf_1135 exopolyphosphatase-like enzyme K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] D Spiaf_2615 rhodanese-related sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Spiaf_2013 rhodanese-related sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Spiaf_1300 rhodanese-related sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Spiaf_0212 serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D Spiaf_2045 cysteine synthase A K01738 cysK; cysteine synthase [EC:2.5.1.47] D Spiaf_0444 homoserine O-succinyltransferase K00651 metA; homoserine O-succinyltransferase/O-acetyltransferase [EC:2.3.1.46 2.3.1.31] D Spiaf_2450 O-succinylhomoserine sulfhydrylase K10764 metZ; O-succinylhomoserine sulfhydrylase [EC:2.5.1.-] B B 09103 Lipid metabolism C 00061 Fatty acid biosynthesis [PATH:sfc00061] D Spiaf_2211 acetyl-CoA carboxylase, carboxyl transferase, alpha subunit K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D Spiaf_2214 acetyl-CoA carboxylase, biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D Spiaf_2213 acetyl/propionyl-CoA carboxylase, alpha subunit K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D Spiaf_2212 acetyl-CoA carboxylase, carboxyl transferase, beta subunit K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D Spiaf_1694 acyl carrier protein K02078 acpP; acyl carrier protein D Spiaf_2287 acyl carrier protein K02078 acpP; acyl carrier protein D Spiaf_0247 malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D Spiaf_2283 3-oxoacyl-(acyl-carrier-protein) synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D Spiaf_0246 3-oxoacyl-(acyl-carrier-protein) synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D Spiaf_2286 3-oxoacyl-(acyl-carrier-protein) synthase K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41] D Spiaf_0249 beta-ketoacyl-acyl-carrier-protein synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D Spiaf_1413 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spiaf_0248 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spiaf_2282 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spiaf_2772 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spiaf_2284 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase K01716 fabA; 3-hydroxyacyl-[acyl-carrier protein] dehydratase / trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:4.2.1.59 5.3.3.14] D Spiaf_2215 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D Spiaf_2285 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D Spiaf_1423 putative paraquat-inducible protein B K00209 fabV; enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44] D Spiaf_0085 AMP-forming long-chain acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1710 AMP-forming long-chain acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1768 AMP-forming long-chain acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_0924 AMP-forming long-chain acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1302 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1303 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 00062 Fatty acid elongation C 00071 Fatty acid degradation [PATH:sfc00071] D Spiaf_2588 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Spiaf_0085 AMP-forming long-chain acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1710 AMP-forming long-chain acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1768 AMP-forming long-chain acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_0924 AMP-forming long-chain acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1302 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1303 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1035 NAD(P)H-nitrite reductase K00529 hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3] D Spiaf_2451 alcohol dehydrogenase, class IV K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D Spiaf_2546 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] C 00073 Cutin, suberine and wax biosynthesis C 00100 Steroid biosynthesis C 00120 Primary bile acid biosynthesis C 00121 Secondary bile acid biosynthesis C 00140 Steroid hormone biosynthesis C 00561 Glycerolipid metabolism [PATH:sfc00561] D Spiaf_2546 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Spiaf_0325 glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30] D Spiaf_2505 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D Spiaf_1047 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D Spiaf_0449 alpha/beta hydrolase family protein K01046 lip; triacylglycerol lipase [EC:3.1.1.3] D Spiaf_0092 glycosyltransferase K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] D Spiaf_0093 glycosyltransferase K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] D Spiaf_0279 alpha-galactosidase K07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22] C 00564 Glycerophospholipid metabolism [PATH:sfc00564] D Spiaf_0333 glycerol-3-phosphate dehydrogenase K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94] D Spiaf_0324 putative dehydrogenase K00111 glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] D Spiaf_1065 putative dehydrogenase K00111 glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] D Spiaf_2505 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D Spiaf_1047 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D Spiaf_2740 glycerophosphoryl diester phosphodiesterase K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46] D Spiaf_2511 glycerophosphoryl diester phosphodiesterase K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46] D Spiaf_2690 glycerophosphoryl diester phosphodiesterase K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46] D Spiaf_1990 putative CDP-diglyceride synthetase/phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41] D Spiaf_2598 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K00995 pgsA; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5] D Spiaf_1296 phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-] D Spiaf_1459 phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase K06132 clsC; cardiolipin synthase C [EC:2.7.8.-] D Spiaf_2513 phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase K06132 clsC; cardiolipin synthase C [EC:2.7.8.-] D Spiaf_2260 phosphatidylglycerophosphate synthase K08744 CRLS; cardiolipin synthase (CMP-forming) [EC:2.7.8.41] C 00565 Ether lipid metabolism C 00600 Sphingolipid metabolism [PATH:sfc00600] D Spiaf_0704 O-glycosyl hydrolase K01201 GBA; glucosylceramidase [EC:3.2.1.45] D Spiaf_0279 alpha-galactosidase K07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22] C 00590 Arachidonic acid metabolism C 00591 Linoleic acid metabolism C 00592 alpha-Linolenic acid metabolism C 01040 Biosynthesis of unsaturated fatty acids B B 09104 Nucleotide metabolism C 00230 Purine metabolism [PATH:sfc00230] D Spiaf_0214 ADP-ribose pyrophosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] D Spiaf_0830 phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D Spiaf_1522 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D Spiaf_1953 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D Spiaf_1956 phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] D Spiaf_1955 folate-dependent phosphoribosylglycinamide formyltransferase PurN K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D Spiaf_0089 phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain protein K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D Spiaf_0088 phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain protein K23270 purSL; phosphoribosylformylglycinamidine synthase subunit PurSL [EC:6.3.5.3] D Spiaf_1954 phosphoribosylaminoimidazole synthetase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] D Spiaf_0477 phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18] D Spiaf_0478 phosphoribosylaminoimidazole carboxylase, PurE protein K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] D Spiaf_1088 phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] D Spiaf_0460 phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] D Spiaf_1611 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D Spiaf_1616 AICAR transformylase/IMP cyclohydrolase PurH K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D Spiaf_1898 PRPP-binding protein, adenine/guanine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D Spiaf_1933 5'/3'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D Spiaf_1187 purine nucleoside phosphorylase I, inosine and guanosine-specific K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1] D Spiaf_1892 hypothetical protein K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4] D Spiaf_1610 inosine-5''-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D Spiaf_0335 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D Spiaf_1133 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66] D Spiaf_2224 aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM-like protein K13481 xdhA; xanthine dehydrogenase small subunit [EC:1.17.1.4] D Spiaf_1608 GMP synthase (glutamine-hydrolyzing) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D Spiaf_2177 IMP dehydrogenase/GMP reductase K00364 guaC; GMP reductase [EC:1.7.1.7] D Spiaf_0747 ribonucleoside-diphosphate reductase, alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Spiaf_0746 ribonucleotide reductase, beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D Spiaf_2303 anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D Spiaf_2414 dGTP triphosphohydrolase K01129 dgt; dGTPase [EC:3.1.5.1] D Spiaf_1825 (p)ppGpp synthetase, RelA/SpoT family K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D Spiaf_2817 exopolyphosphatase K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40] D Spiaf_2412 hypothetical protein K07816 E2.7.6.5; GTP pyrophosphokinase [EC:2.7.6.5] D Spiaf_2447 family 3 adenylate cyclase K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1] D Spiaf_0189 family 3 adenylate cyclase K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1] D Spiaf_0207 family 3 adenylate cyclase K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1] D Spiaf_0938 family 3 adenylate cyclase K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1] D Spiaf_2712 family 3 adenylate cyclase K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1] D Spiaf_1040 PAS domain S-box K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1] D Spiaf_0471 family 3 adenylate cyclase K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1] D Spiaf_1512 family 3 adenylate cyclase K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1] D Spiaf_1256 family 3 adenylate cyclase K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1] D Spiaf_0918 adenylyl cyclase CyaB, putative K05873 cyaB; adenylate cyclase, class 2 [EC:4.6.1.1] D Spiaf_1609 adenylosuccinate synthase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D Spiaf_2871 adenosine deaminase K01488 add; adenosine deaminase [EC:3.5.4.4] D Spiaf_1186 adenosine deaminase K01488 add; adenosine deaminase [EC:3.5.4.4] D Spiaf_1975 metallophosphoesterase, MG_246/BB_0505 family K09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16] D Spiaf_2149 adenylate kinase family protein K00939 adk; adenylate kinase [EC:2.7.4.3] D Spiaf_2051 putative phosphohydrolase K03651 cpdA; 3',5'-cyclic-AMP phosphodiesterase [EC:3.1.4.53] D Spiaf_0152 Calcineurin-like phosphoesterase K01525 apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [EC:3.6.1.41] C 00240 Pyrimidine metabolism [PATH:sfc00240] D Spiaf_1895 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D Spiaf_1848 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D Spiaf_1896 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D Spiaf_1916 aspartate carbamoyltransferase K00608 pyrBI; aspartate carbamoyltransferase [EC:2.1.3.2] D Spiaf_2759 dihydroorotase, homodimeric type K01465 URA4; dihydroorotase [EC:3.5.2.3] D Spiaf_1350 dihydroorotate dehydrogenase family protein K17828 pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14] D Spiaf_1351 2-polyprenylphenol hydroxylase-like oxidoreductase K02823 pyrDII; dihydroorotate dehydrogenase electron transfer subunit D Spiaf_0536 dihydroorotate dehydrogenase K00226 pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1] D Spiaf_0539 dihydroorotate dehydrogenase K00226 pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1] D Spiaf_2567 orotidine 5''-phosphate decarboxylase, subfamily 2 K13421 UMPS; uridine monophosphate synthetase [EC:2.4.2.10 4.1.1.23] D Spiaf_0654 uridylate kinase, putative K09903 pyrH; uridylate kinase [EC:2.7.4.22] D Spiaf_0335 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D Spiaf_1985 MAF protein K06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-] D Spiaf_2675 CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2] D Spiaf_1516 cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25] D Spiaf_2426 cytidylate kinase, putative K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25] D Spiaf_2184 uridine kinase K00876 udk; uridine kinase [EC:2.7.1.48] D Spiaf_1933 5'/3'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D Spiaf_2151 uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9] D Spiaf_1975 metallophosphoesterase, MG_246/BB_0505 family K09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16] D Spiaf_1442 pyrimidine-nucleoside phosphorylase K00756 pdp; pyrimidine-nucleoside phosphorylase [EC:2.4.2.2] D Spiaf_1192 cytidine deaminase, homotetrameric K01489 cdd; cytidine deaminase [EC:3.5.4.5] D Spiaf_2303 anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D Spiaf_1275 deoxycytidine triphosphate deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13] D Spiaf_0747 ribonucleoside-diphosphate reductase, alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Spiaf_0746 ribonucleotide reductase, beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D Spiaf_1548 thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D Spiaf_1534 deoxyuridine 5'-triphosphate nucleotidohydrolase Dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D Spiaf_2813 thymidylate synthase, flavin-dependent K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148] B B 09105 Amino acid metabolism C 00250 Alanine, aspartate and glutamate metabolism [PATH:sfc00250] D Spiaf_2831 aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16] D Spiaf_0678 L-asparaginase/GlutRNAGln amidotransferase subunit D K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1] D Spiaf_1332 aspartate--ammonia ligase, AsnA-type K01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1] D Spiaf_1925 aspartate/tyrosine/aromatic aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D Spiaf_0410 aspartate/tyrosine/aromatic aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D Spiaf_0191 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D Spiaf_2010 argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D Spiaf_1609 adenylosuccinate synthase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D Spiaf_1611 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D Spiaf_1916 aspartate carbamoyltransferase K00608 pyrBI; aspartate carbamoyltransferase [EC:2.1.3.2] D Spiaf_0177 NAD-dependent aldehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Spiaf_1890 glutamate synthase family protein K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] D Spiaf_1889 NADH/NADPH-dependent glutamate synthase small subunit K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] D Spiaf_2825 NADPH-dependent glutamate synthase, homotetrameric K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] D Spiaf_2158 glutamate dehydrogenase/leucine dehydrogenase K00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] D Spiaf_0307 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Spiaf_1199 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Spiaf_1895 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D Spiaf_1848 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D Spiaf_1896 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D Spiaf_0089 phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain protein K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D Spiaf_2543 glucosamine--fructose-6-phosphate aminotransferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Spiaf_1953 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C 00260 Glycine, serine and threonine metabolism [PATH:sfc00260] D Spiaf_0594 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Spiaf_2764 aspartokinase K12524 thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3] D Spiaf_0595 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Spiaf_2465 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D Spiaf_2654 phosphoserine phosphatase/homoserine phosphotransferase K02203 thrH; phosphoserine / homoserine phosphotransferase [EC:3.1.3.3 2.7.1.39] D Spiaf_2763 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D Spiaf_0360 threonine aldolase K01620 ltaE; threonine aldolase [EC:4.1.2.48] D Spiaf_2484 glycine/serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Spiaf_1156 fructose-2,6-bisphosphatase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D Spiaf_0526 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Spiaf_2706 phosphoglycerate dehydrogenase-like oxidoreductase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Spiaf_2701 phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D Spiaf_1783 phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] D Spiaf_2755 fructose-2,6-bisphosphatase K22305 psp; phosphoserine phosphatase [EC:3.1.3.3] D Spiaf_0481 glycine dehydrogenase, decarboxylating K00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2] D Spiaf_1800 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_0773 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_0009 glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein D Spiaf_0713 threonine ammonia-lyase, biosynthetic, long form K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19] D Spiaf_2547 tryptophan synthase, alpha subunit K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D Spiaf_2548 tryptophan synthase, beta subunit K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D Spiaf_2367 tryptophan synthase, beta subunit K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D Spiaf_0179 2,4-diaminobutyrate 4-transaminase K00836 ectB; diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76] D Spiaf_2837 diaminobutyrate--2-oxoglutarate aminotransferase K00836 ectB; diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76] D Spiaf_2836 diaminobutyrate acetyltransferase K06718 ectA; L-2,4-diaminobutyric acid acetyltransferase [EC:2.3.1.178] D Spiaf_2838 hypothetical protein K06720 ectC; L-ectoine synthase [EC:4.2.1.108] C 00270 Cysteine and methionine metabolism [PATH:sfc00270] D Spiaf_0212 serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D Spiaf_2045 cysteine synthase A K01738 cysK; cysteine synthase [EC:2.5.1.47] D Spiaf_2562 bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D Spiaf_0490 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D Spiaf_2290 methionine synthase II (cobalamin-independent) K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D Spiaf_0011 S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D Spiaf_0897 spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16] D Spiaf_2561 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase K01243 mtnN; adenosylhomocysteine nucleosidase [EC:3.2.2.9] D Spiaf_1892 hypothetical protein K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4] D Spiaf_1723 GAF domain-containing protein K08968 msrC; L-methionine (R)-S-oxide reductase [EC:1.8.4.14] D Spiaf_0875 DNA-methyltransferase Dcm K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Spiaf_0010 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D Spiaf_0594 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Spiaf_2764 aspartokinase K12524 thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3] D Spiaf_0595 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Spiaf_2465 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D Spiaf_0444 homoserine O-succinyltransferase K00651 metA; homoserine O-succinyltransferase/O-acetyltransferase [EC:2.3.1.46 2.3.1.31] D Spiaf_2044 OAH/OAS sulfhydrylase K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49] D Spiaf_2450 O-succinylhomoserine sulfhydrylase K10764 metZ; O-succinylhomoserine sulfhydrylase [EC:2.5.1.-] D Spiaf_0676 branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Spiaf_2615 rhodanese-related sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Spiaf_2013 rhodanese-related sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Spiaf_1300 rhodanese-related sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Spiaf_2292 L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D Spiaf_2449 cysteine synthase B K12339 cysM; S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent) [EC:2.5.1.144] D Spiaf_2706 phosphoglycerate dehydrogenase-like oxidoreductase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Spiaf_2701 phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] C 00280 Valine, leucine and isoleucine degradation [PATH:sfc00280] D Spiaf_0676 branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Spiaf_2502 pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit K11381 bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4] D Spiaf_1800 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_0773 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_1424 beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase K00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31] D Spiaf_2546 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Spiaf_2588 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Spiaf_0377 3-hydroxy-3-methylglutaryl CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] C 00290 Valine, leucine and isoleucine biosynthesis [PATH:sfc00290] D Spiaf_0713 threonine ammonia-lyase, biosynthetic, long form K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19] D Spiaf_2344 3-isopropylmalate dehydratase, large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D Spiaf_2345 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D Spiaf_2757 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] D Spiaf_1663 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Spiaf_1664 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D Spiaf_0524 ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D Spiaf_2381 dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D Spiaf_1665 dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D Spiaf_0676 branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Spiaf_2136 alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase K00835 avtA; valine--pyruvate aminotransferase [EC:2.6.1.66] D Spiaf_1925 aspartate/tyrosine/aromatic aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D Spiaf_0410 aspartate/tyrosine/aromatic aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D Spiaf_1894 2-isopropylmalate synthase/homocitrate synthase family protein K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] D Spiaf_2397 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] C 00300 Lysine biosynthesis [PATH:sfc00300] D Spiaf_2465 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D Spiaf_0594 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Spiaf_2764 aspartokinase K12524 thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3] D Spiaf_0595 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Spiaf_2205 dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D Spiaf_2204 dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] D Spiaf_0192 ornithine/acetylornithine aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D Spiaf_1724 LL-diaminopimelate aminotransferase K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83] D Spiaf_0086 diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D Spiaf_2242 transcriptional regulator with HTH domain and aminotransferase domain K05825 LYSN; 2-aminoadipate transaminase [EC:2.6.1.-] D Spiaf_1715 UDP-N-acetylmuramyl-tripeptide synthetase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D Spiaf_2121 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] C 00310 Lysine degradation [PATH:sfc00310] D Spiaf_1800 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_0773 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_2588 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Spiaf_0177 NAD-dependent aldehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Spiaf_1666 KamA family protein K01843 kamA; lysine 2,3-aminomutase [EC:5.4.3.2] D Spiaf_2546 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] C 00220 Arginine biosynthesis [PATH:sfc00220] D Spiaf_1137 ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3] D Spiaf_0191 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D Spiaf_2010 argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D Spiaf_1193 arginine deiminase K01478 arcA; arginine deiminase [EC:3.5.3.6] D Spiaf_0089 phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain protein K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D Spiaf_0307 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Spiaf_1199 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Spiaf_2158 glutamate dehydrogenase/leucine dehydrogenase K00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] D Spiaf_1925 aspartate/tyrosine/aromatic aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D Spiaf_0410 aspartate/tyrosine/aromatic aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D Spiaf_1271 amino-acid N-acetyltransferase K14682 argAB; amino-acid N-acetyltransferase [EC:2.3.1.1] D Spiaf_2538 glutamate N-acetyltransferase/amino-acid acetyltransferase K00620 argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1] D Spiaf_0193 acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8] D Spiaf_0194 acetylglutamate semialdehyde dehydrogenase K00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38] D Spiaf_0192 ornithine/acetylornithine aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D Spiaf_2053 acetylornithine deacetylase ArgE K01438 argE; acetylornithine deacetylase [EC:3.5.1.16] C 00330 Arginine and proline metabolism [PATH:sfc00330] D Spiaf_0649 arginine decarboxylase, biosynthetic K01585 speA; arginine decarboxylase [EC:4.1.1.19] D Spiaf_0484 peptidylarginine deiminase-like enzyme K10536 aguA; agmatine deiminase [EC:3.5.3.12] D Spiaf_0485 putative amidohydrolase K12251 aguB; N-carbamoylputrescine amidase [EC:3.5.1.53] D Spiaf_0897 spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16] D Spiaf_0651 carboxynorspermidine decarboxylase K13747 nspC; carboxynorspermidine decarboxylase [EC:4.1.1.96] D Spiaf_2546 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Spiaf_1828 pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2] D Spiaf_2050 glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11] D Spiaf_2049 gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] C 00340 Histidine metabolism [PATH:sfc00340] D Spiaf_2230 ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17] D Spiaf_2229 ATP phosphoribosyltransferase involved in histidine biosynthesis K02502 hisZ; ATP phosphoribosyltransferase regulatory subunit D Spiaf_2469 phosphoribosyl-AMP cyclohydrolase K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19] D Spiaf_2758 phosphoribosyl-ATP pyrophosphohydrolase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16] D Spiaf_2475 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10] D Spiaf_2474 imidazoleglycerol phosphate synthase, cyclase subunit K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10] D Spiaf_2231 imidazoleglycerol-phosphate dehydratase K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19] D Spiaf_0973 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Spiaf_1559 inositol monophosphatase/fructose-1,6-bisphosphatase family protein K05602 hisN; histidinol-phosphatase [EC:3.1.3.15] D Spiaf_1422 histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23] D Spiaf_1760 histidine ammonia-lyase K01745 hutH; histidine ammonia-lyase [EC:4.3.1.3] D Spiaf_2546 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] C 00350 Tyrosine metabolism [PATH:sfc00350] D Spiaf_0973 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Spiaf_2451 alcohol dehydrogenase, class IV K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D Spiaf_0177 NAD-dependent aldehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] C 00360 Phenylalanine metabolism [PATH:sfc00360] D Spiaf_0973 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Spiaf_1698 ferredoxin subunit of nitrite reductase and ring-hydroxylating dioxygenase K05710 hcaC; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin component D Spiaf_1035 NAD(P)H-nitrite reductase K00529 hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3] C 00380 Tryptophan metabolism [PATH:sfc00380] D Spiaf_1800 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_0773 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_2588 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Spiaf_2546 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:sfc00400] D Spiaf_1264 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D Spiaf_2052 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D Spiaf_2028 3-dehydroquinate synthetase K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4] D Spiaf_2725 shikimate 5-dehydrogenase K13832 aroDE; 3-dehydroquinate dehydratase / shikimate dehydrogenase [EC:4.2.1.10 1.1.1.25] D Spiaf_1814 shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71] D Spiaf_0348 shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71] D Spiaf_2628 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19] D Spiaf_2857 chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5] D Spiaf_2551 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D Spiaf_2550 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase K13497 trpGD; anthranilate synthase/phosphoribosyltransferase [EC:4.1.3.27 2.4.2.18] D Spiaf_2547 tryptophan synthase, alpha subunit K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D Spiaf_2548 tryptophan synthase, beta subunit K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D Spiaf_2367 tryptophan synthase, beta subunit K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D Spiaf_2643 prephenate dehydratase K14170 pheA; chorismate mutase / prephenate dehydratase [EC:5.4.99.5 4.2.1.51] D Spiaf_1492 chorismate mutase K06208 aroH; chorismate mutase [EC:5.4.99.5] D Spiaf_0973 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] B B 09106 Metabolism of other amino acids C 00410 beta-Alanine metabolism [PATH:sfc00410] D Spiaf_2827 L-aspartate-alpha-decarboxylase K01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11] D Spiaf_2546 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Spiaf_2829 pantoate--beta-alanine ligase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1] C 00430 Taurine and hypotaurine metabolism [PATH:sfc00430] D Spiaf_0942 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D Spiaf_0943 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D Spiaf_2203 phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D Spiaf_2497 acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D Spiaf_1162 acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] C 00440 Phosphonate and phosphinate metabolism C 00450 Selenocompound metabolism [PATH:sfc00450] D Spiaf_2562 bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D Spiaf_0490 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D Spiaf_2290 methionine synthase II (cobalamin-independent) K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D Spiaf_1037 cysteine desulfurase-like protein, SufS subfamily K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16] D Spiaf_0709 thioredoxin-disulfide reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9] D Spiaf_1414 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] C 00460 Cyanoamino acid metabolism [PATH:sfc00460] D Spiaf_0288 beta-glucosidase-like glycosyl hydrolase K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spiaf_0357 beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase K05350 bglB; beta-glucosidase [EC:3.2.1.21] D Spiaf_2170 beta-galactosidase K05350 bglB; beta-glucosidase [EC:3.2.1.21] D Spiaf_0942 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D Spiaf_0943 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D Spiaf_0678 L-asparaginase/GlutRNAGln amidotransferase subunit D K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1] D Spiaf_1332 aspartate--ammonia ligase, AsnA-type K01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1] D Spiaf_2484 glycine/serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] C 00470 D-Amino acid metabolism [PATH:sfc00470] D Spiaf_2746 alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D Spiaf_1716 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D Spiaf_0089 phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain protein K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D Spiaf_1652 glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3] D Spiaf_1416 UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D Spiaf_0086 diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] C 00480 Glutathione metabolism [PATH:sfc00480] D Spiaf_0942 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D Spiaf_0943 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D Spiaf_0314 aminoacyl-histidine dipeptidase K01270 pepD; dipeptidase D [EC:3.4.13.-] D Spiaf_1226 isocitrate dehydrogenase, NADP-dependent, monomeric type K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42] D Spiaf_1268 6-phosphogluconate dehydrogenase, decarboxylating K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] D Spiaf_0198 glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D Spiaf_0897 spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16] B B 09107 Glycan biosynthesis and metabolism C 00510 N-Glycan biosynthesis C 00513 Various types of N-glycan biosynthesis C 00512 Mucin type O-glycan biosynthesis C 00515 Mannose type O-glycan biosynthesis C 00514 Other types of O-glycan biosynthesis C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin C 00533 Glycosaminoglycan biosynthesis - keratan sulfate C 00531 Glycosaminoglycan degradation C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series C 00604 Glycosphingolipid biosynthesis - ganglio series C 00511 Other glycan degradation D Spiaf_0704 O-glycosyl hydrolase K01201 GBA; glucosylceramidase [EC:3.2.1.45] C 00540 Lipopolysaccharide biosynthesis C 00542 O-Antigen repeat unit biosynthesis [PATH:sfc00542] D Spiaf_0067 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] C 00541 O-Antigen nucleotide sugar biosynthesis [PATH:sfc00541] D Spiaf_0260 UDP-glucose pyrophosphorylase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Spiaf_2394 UDP-glucose-4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Spiaf_0064 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Spiaf_0061 nucleoside-diphosphate-sugar epimerase K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6] D Spiaf_0031 glucose-1-phosphate thymidylyltransferase, short form K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D Spiaf_0030 dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D Spiaf_0109 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] D Spiaf_1179 mannose-6-phosphate isomerase, class I K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] D Spiaf_0677 mannose-1-phosphate guanylyltransferase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8] C 00550 Peptidoglycan biosynthesis [PATH:sfc00550] D Spiaf_2765 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D Spiaf_2490 UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D Spiaf_2428 UDP-N-acetylmuramate--alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D Spiaf_1416 UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D Spiaf_1715 UDP-N-acetylmuramyl-tripeptide synthetase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D Spiaf_1716 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D Spiaf_2121 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D Spiaf_1989 undecaprenyl diphosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D Spiaf_0596 putative bacitracin resistance protein K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D Spiaf_2120 phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D Spiaf_0588 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D Spiaf_1914 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Spiaf_0345 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Spiaf_0451 membrane carboxypeptidase/penicillin-binding protein PbpC K05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28] D Spiaf_1507 penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] D Spiaf_0777 cell division protein FtsI/penicillin-binding protein 2 K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] D Spiaf_0982 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D Spiaf_1438 D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] C 00552 Teichoic acid biosynthesis [PATH:sfc00552] D Spiaf_0596 putative bacitracin resistance protein K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D Spiaf_0067 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D Spiaf_2776 teichoic acid biosynthesis protein K05946 tagA; N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase [EC:2.4.1.187] D Spiaf_1880 transcriptional regulator K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-] D Spiaf_0092 glycosyltransferase K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] D Spiaf_0093 glycosyltransferase K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] C 00571 Lipoarabinomannan (LAM) biosynthesis C 00572 Arabinogalactan biosynthesis - Mycobacterium C 00543 Exopolysaccharide biosynthesis [PATH:sfc00543] D Spiaf_0067 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D Spiaf_0629 putative membrane protein involved in D-alanine export K19294 algI; alginate O-acetyltransferase complex protein AlgI D Spiaf_0630 hypothetical protein K19295 algJ; alginate O-acetyltransferase complex protein AlgJ D Spiaf_0628 Alginate O-acetyl transferase AlgF K19296 algF; alginate O-acetyltransferase complex protein AlgF D Spiaf_0212 serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] B B 09108 Metabolism of cofactors and vitamins C 00730 Thiamine metabolism [PATH:sfc00730] D Spiaf_1651 ribosome small subunit-dependent GTPase A K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D Spiaf_2164 ribosome small subunit-dependent GTPase A K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D Spiaf_1488 thiamine pyrophosphokinase K00949 thiN; thiamine pyrophosphokinase [EC:2.7.6.2] D Spiaf_2149 adenylate kinase family protein K00939 adk; adenylate kinase [EC:2.7.4.3] C 00740 Riboflavin metabolism [PATH:sfc00740] D Spiaf_0827 GTP cyclohydrolase II K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25] D Spiaf_1325 riboflavin biosynthesis protein RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D Spiaf_1235 haloacid dehalogenase superfamily enzyme, subfamily IA K20862 yigB; FMN hydrolase / 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:3.1.3.102 3.1.3.104] D Spiaf_1323 3,4-dihydroxy-2-butanone 4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12] D Spiaf_1322 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78] D Spiaf_1324 riboflavin synthase, alpha subunit K00793 ribE; riboflavin synthase [EC:2.5.1.9] D Spiaf_1537 FAD synthase K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2] D Spiaf_0214 ADP-ribose pyrophosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] C 00750 Vitamin B6 metabolism [PATH:sfc00750] D Spiaf_2701 phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D Spiaf_2763 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D Spiaf_1658 pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6] D Spiaf_1659 pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6] C 00760 Nicotinate and nicotinamide metabolism [PATH:sfc00760] D Spiaf_2831 aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16] D Spiaf_2832 quinolinate synthetase complex, A subunit K03517 nadA; quinolinate synthase [EC:2.5.1.72] D Spiaf_2833 nicotinate-nucleotide pyrophosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19] D Spiaf_1106 putative nicotinate phosphoribosyltransferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21] D Spiaf_1187 purine nucleoside phosphorylase I, inosine and guanosine-specific K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1] D Spiaf_2819 cytidyltransferase-related enzyme K06211 nadR; HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22] D Spiaf_1933 5'/3'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D Spiaf_1881 nicotinate/nicotinamide nucleotide adenylyltransferase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18] D Spiaf_2855 Zn-finger containing NTP pyrophosphohydrolase K03426 NUDT12_13; NAD+ diphosphatase [EC:3.6.1.22] D Spiaf_2805 NAD synthase K01950 E6.3.5.1; NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1] D Spiaf_1938 competence/damage-inducible protein CinA-like protein K03743 pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42] D Spiaf_1107 nicotinamidase-like amidase K08281 pncA; nicotinamidase/pyrazinamidase [EC:3.5.1.19 3.5.1.-] D Spiaf_2568 NAD-dependent protein deacetylase, SIR2 family K12410 cobB; NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313] D Spiaf_2131 putative sugar kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23] D Spiaf_2788 hypothetical protein K00324 pntA; proton-translocating NAD(P)+ transhydrogenase subunit alpha [EC:7.1.1.1] D Spiaf_2789 NAD/NADP transhydrogenase alpha subunit K00324 pntA; proton-translocating NAD(P)+ transhydrogenase subunit alpha [EC:7.1.1.1] D Spiaf_2787 NAD/NADP transhydrogenase beta subunit K00325 pntB; proton-translocating NAD(P)+ transhydrogenase subunit beta [EC:7.1.1.1] D Spiaf_0177 NAD-dependent aldehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] C 00770 Pantothenate and CoA biosynthesis [PATH:sfc00770] D Spiaf_1663 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Spiaf_1664 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D Spiaf_0524 ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D Spiaf_2381 dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D Spiaf_1665 dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D Spiaf_2830 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11] D Spiaf_2829 pantoate--beta-alanine ligase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1] D Spiaf_2828 pantothenate kinase, type III K03525 coaX; type III pantothenate kinase [EC:2.7.1.33] D Spiaf_0758 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5] D Spiaf_1696 pantetheine-phosphate adenylyltransferase K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3] D Spiaf_2715 dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24] D Spiaf_1075 holo-(acyl-carrier-protein) synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7] D Spiaf_1607 hypothetical protein K08682 acpH; acyl carrier protein phosphodiesterase [EC:3.1.4.14] D Spiaf_0676 branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Spiaf_2827 L-aspartate-alpha-decarboxylase K01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11] D Spiaf_2546 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] C 00780 Biotin metabolism [PATH:sfc00780] D Spiaf_2286 3-oxoacyl-(acyl-carrier-protein) synthase K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41] D Spiaf_0249 beta-ketoacyl-acyl-carrier-protein synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D Spiaf_1413 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spiaf_0248 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spiaf_2282 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spiaf_2772 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spiaf_2215 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D Spiaf_2285 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D Spiaf_1318 birA, biotin-(acetyl-CoA-carboxylase) ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] C 00785 Lipoic acid metabolism [PATH:sfc00785] D Spiaf_2791 lipoate-protein ligase A K23734 lipM; lipoyl(octanoyl) transferase [EC:2.3.1.181] D Spiaf_1743 lipoate synthase K03644 lipA; lipoyl synthase [EC:2.8.1.8] D Spiaf_2858 lipoate-protein ligase A K03800 lplA; lipoate---protein ligase [EC:6.3.1.20] D Spiaf_1800 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_0773 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_1803 pyruvate dehydrogenase E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D Spiaf_1802 pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D Spiaf_1801 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Spiaf_2502 pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit K11381 bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4] D Spiaf_0481 glycine dehydrogenase, decarboxylating K00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2] D Spiaf_0009 glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein C 00790 Folate biosynthesis [PATH:sfc00790] D Spiaf_1618 hypothetical protein K09007 folE2; GTP cyclohydrolase IB [EC:3.5.4.16] D Spiaf_1272 FolB domain protein K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81] D Spiaf_1520 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] D Spiaf_1072 dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15] D Spiaf_1421 folylpolyglutamate synthase/dihydrofolate synthase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] D Spiaf_0827 GTP cyclohydrolase II K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25] D Spiaf_2024 anthranilate/para-aminobenzoate synthase component I K01665 pabB; para-aminobenzoate synthetase component I [EC:2.6.1.85] D Spiaf_2025 branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase K02619 pabC; 4-amino-4-deoxychorismate lyase [EC:4.1.3.38] D Spiaf_0419 7-cyano-7-deazaguanine reductase K09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13] C 00670 One carbon pool by folate [PATH:sfc00670] D Spiaf_0366 formyltetrahydrofolate synthetase K00288 MTHFD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3] D Spiaf_1619 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] D Spiaf_2484 glycine/serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Spiaf_1955 folate-dependent phosphoribosylglycinamide formyltransferase PurN K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D Spiaf_1616 AICAR transformylase/IMP cyclohydrolase PurH K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D Spiaf_1091 methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D Spiaf_0490 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D Spiaf_2813 thymidylate synthase, flavin-dependent K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148] D Spiaf_0302 5,10-methenyltetrahydrofolate synthetase K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] C 00830 Retinol metabolism C 00860 Porphyrin metabolism [PATH:sfc00860] D Spiaf_1924 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Spiaf_1022 flavodoxin K00230 hemG; menaquinone-dependent protoporphyrinogen oxidase [EC:1.3.5.3] D Spiaf_0394 flavodoxin K00230 hemG; menaquinone-dependent protoporphyrinogen oxidase [EC:1.3.5.3] D Spiaf_2750 ATP:cob(I)alamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:sfc00130] D Spiaf_1347 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74] D Spiaf_1703 putative NADPH-quinone reductase (modulator of drug activity B) K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2] D Spiaf_0137 NAD(P)H:quinone oxidoreductase, type IV K03809 wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2] D Spiaf_2472 hypothetical protein K09834 VTE1; tocopherol cyclase [EC:5.5.1.24] B B 09109 Metabolism of terpenoids and polyketides C 00900 Terpenoid backbone biosynthesis [PATH:sfc00900] D Spiaf_2588 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Spiaf_0377 3-hydroxy-3-methylglutaryl CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D Spiaf_0375 hydroxymethylglutaryl-CoA reductase, degradative K00054 mvaA; hydroxymethylglutaryl-CoA reductase [EC:1.1.1.88] D Spiaf_0372 mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36] D Spiaf_0374 diphosphomevalonate decarboxylase K01597 MVD; diphosphomevalonate decarboxylase [EC:4.1.1.33] D Spiaf_0376 isopentenyl-diphosphate delta-isomerase, type 2 K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2] D Spiaf_1660 geranylgeranyl pyrophosphate synthase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] D Spiaf_1989 undecaprenyl diphosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] C 00902 Monoterpenoid biosynthesis C 00909 Sesquiterpenoid and triterpenoid biosynthesis C 00904 Diterpenoid biosynthesis C 00906 Carotenoid biosynthesis [PATH:sfc00906] D Spiaf_1661 phytoene/squalene synthetase K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32] D Spiaf_1285 Lycopene cyclase protein K06443 lcyB; lycopene beta-cyclase [EC:5.5.1.19] D Spiaf_2627 fatty acid hydroxylase-like protein K15746 crtZ; beta-carotene 3-hydroxylase [EC:1.14.15.24] D Spiaf_2800 phytoene desaturase K10210 crtP; diapolycopene oxygenase [EC:1.14.99.44] C 00905 Brassinosteroid biosynthesis C 00981 Insect hormone biosynthesis C 00908 Zeatin biosynthesis C 00903 Limonene degradation D Spiaf_2546 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] C 00907 Pinene, camphor and geraniol degradation C 01052 Type I polyketide structures C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides C 01051 Biosynthesis of ansamycins D Spiaf_2756 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D Spiaf_0126 transketolase, beta subunit K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D Spiaf_0127 transketolase, alpha subunit K00615 E2.2.1.1; transketolase [EC:2.2.1.1] C 01059 Biosynthesis of enediyne antibiotics C 01056 Biosynthesis of type II polyketide backbone C 01057 Biosynthesis of type II polyketide products C 00253 Tetracycline biosynthesis C 00523 Polyketide sugar unit biosynthesis [PATH:sfc00523] D Spiaf_0031 glucose-1-phosphate thymidylyltransferase, short form K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D Spiaf_0030 dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D Spiaf_0109 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] C 01054 Nonribosomal peptide structures C 01053 Biosynthesis of siderophore group nonribosomal peptides C 01055 Biosynthesis of vancomycin group antibiotics D Spiaf_0030 dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] B B 09110 Biosynthesis of other secondary metabolites C 00940 Phenylpropanoid biosynthesis C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis C 00941 Flavonoid biosynthesis C 00944 Flavone and flavonol biosynthesis C 00942 Anthocyanin biosynthesis C 00943 Isoflavonoid biosynthesis C 00946 Degradation of flavonoids [PATH:sfc00946] D Spiaf_0288 beta-glucosidase-like glycosyl hydrolase K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spiaf_0357 beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase K05350 bglB; beta-glucosidase [EC:3.2.1.21] D Spiaf_2170 beta-galactosidase K05350 bglB; beta-glucosidase [EC:3.2.1.21] C 00901 Indole alkaloid biosynthesis C 00403 Indole diterpene alkaloid biosynthesis C 00950 Isoquinoline alkaloid biosynthesis C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis C 00996 Biosynthesis of various alkaloids C 00232 Caffeine metabolism C 00965 Betalain biosynthesis C 00966 Glucosinolate biosynthesis C 00402 Benzoxazinoid biosynthesis C 00311 Penicillin and cephalosporin biosynthesis C 00332 Carbapenem biosynthesis [PATH:sfc00332] D Spiaf_2050 glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11] D Spiaf_2049 gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] C 00261 Monobactam biosynthesis [PATH:sfc00261] D Spiaf_0594 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Spiaf_2764 aspartokinase K12524 thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3] D Spiaf_0595 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Spiaf_2205 dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D Spiaf_2204 dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] C 00331 Clavulanic acid biosynthesis C 00521 Streptomycin biosynthesis [PATH:sfc00521] D Spiaf_1278 glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D Spiaf_2818 transcriptional regulator/sugar kinase K25026 glk; glucokinase [EC:2.7.1.2] D Spiaf_0830 phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D Spiaf_0242 inositol monophosphatase/fructose-1,6-bisphosphatase family protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D Spiaf_0031 glucose-1-phosphate thymidylyltransferase, short form K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D Spiaf_0030 dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D Spiaf_0109 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] C 00524 Neomycin, kanamycin and gentamicin biosynthesis D Spiaf_1278 glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D Spiaf_2818 transcriptional regulator/sugar kinase K25026 glk; glucokinase [EC:2.7.1.2] C 00525 Acarbose and validamycin biosynthesis [PATH:sfc00525] D Spiaf_0031 glucose-1-phosphate thymidylyltransferase, short form K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D Spiaf_0030 dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] C 00401 Novobiocin biosynthesis D Spiaf_0973 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] C 00404 Staurosporine biosynthesis C 00405 Phenazine biosynthesis D Spiaf_2551 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] C 00333 Prodigiosin biosynthesis D Spiaf_0247 malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D Spiaf_1413 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spiaf_0248 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spiaf_2282 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spiaf_2772 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] C 00254 Aflatoxin biosynthesis C 00998 Biosynthesis of various antibiotics D Spiaf_1694 acyl carrier protein K02078 acpP; acyl carrier protein D Spiaf_2287 acyl carrier protein K02078 acpP; acyl carrier protein C 00999 Biosynthesis of various plant secondary metabolites [PATH:sfc00999] D Spiaf_0011 S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D Spiaf_2725 shikimate 5-dehydrogenase K13832 aroDE; 3-dehydroquinate dehydratase / shikimate dehydrogenase [EC:4.2.1.10 1.1.1.25] D Spiaf_0288 beta-glucosidase-like glycosyl hydrolase K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spiaf_0357 beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase K05350 bglB; beta-glucosidase [EC:3.2.1.21] D Spiaf_2170 beta-galactosidase K05350 bglB; beta-glucosidase [EC:3.2.1.21] C 00997 Biosynthesis of various other secondary metabolites B B 09111 Xenobiotics biodegradation and metabolism C 00362 Benzoate degradation D Spiaf_2588 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00627 Aminobenzoate degradation D Spiaf_1269 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] C 00364 Fluorobenzoate degradation C 00625 Chloroalkane and chloroalkene degradation [PATH:sfc00625] D Spiaf_2451 alcohol dehydrogenase, class IV K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D Spiaf_2546 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] C 00361 Chlorocyclohexane and chlorobenzene degradation C 00623 Toluene degradation C 00622 Xylene degradation C 00633 Nitrotoluene degradation C 00642 Ethylbenzene degradation C 00643 Styrene degradation C 00791 Atrazine degradation C 00930 Caprolactam degradation C 00363 Bisphenol degradation C 00621 Dioxin degradation C 00626 Naphthalene degradation [PATH:sfc00626] D Spiaf_2451 alcohol dehydrogenase, class IV K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] C 00624 Polycyclic aromatic hydrocarbon degradation C 00365 Furfural degradation C 00984 Steroid degradation C 00980 Metabolism of xenobiotics by cytochrome P450 C 00982 Drug metabolism - cytochrome P450 C 00983 Drug metabolism - other enzymes B B 09112 Not included in regular maps C 09113 Global maps only # A09120 Genetic Information Processing B B 09121 Transcription C 03020 RNA polymerase [PATH:sfc03020] D Spiaf_0548 DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D Spiaf_0549 DNA-directed RNA polymerase, beta'' subunit, predominant form K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D Spiaf_0577 DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D Spiaf_1069 RNA polymerase Rpb6 K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] C 03022 Basal transcription factors D Spiaf_2723 DNA/RNA helicase, superfamily II K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] C 03040 Spliceosome B B 09122 Translation C 03010 Ribosome [PATH:sfc03010] D Spiaf_1515 ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1 D Spiaf_1986 ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D Spiaf_0560 ribosomal protein S3, bacterial type K02982 RP-S3; small subunit ribosomal protein S3 D Spiaf_1720 ribosomal protein S4, bacterial/organelle type K02986 RP-S4; small subunit ribosomal protein S4 D Spiaf_0571 ribosomal protein S5, bacterial/organelle type K02988 RP-S5; small subunit ribosomal protein S5 D Spiaf_1999 ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6 D Spiaf_0551 ribosomal protein S7, bacterial/organelle K02992 RP-S7; small subunit ribosomal protein S7 D Spiaf_0568 ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D Spiaf_0666 ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D Spiaf_0553 ribosomal protein S10, bacterial/organelle K02946 RP-S10; small subunit ribosomal protein S10 D Spiaf_0576 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D Spiaf_0550 ribosomal protein S12, bacterial/organelle K02950 RP-S12; small subunit ribosomal protein S12 D Spiaf_0575 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D Spiaf_0567 ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D Spiaf_1536 ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D Spiaf_1212 ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16 D Spiaf_0563 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D Spiaf_1997 ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18 D Spiaf_0558 ribosomal protein S19, bacterial/organelle K02965 RP-S19; small subunit ribosomal protein S19 D Spiaf_1944 ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20 D Spiaf_1445 ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21 D Spiaf_0545 ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D Spiaf_0557 ribosomal protein L2, bacterial/organellar K02886 RP-L2; large subunit ribosomal protein L2 D Spiaf_0554 50S ribosomal protein L3, bacterial K02906 RP-L3; large subunit ribosomal protein L3 D Spiaf_0555 50S ribosomal protein L4, bacterial/organelle K02926 RP-L4; large subunit ribosomal protein L4 D Spiaf_0566 ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D Spiaf_0569 ribosomal protein L6, bacterial type K02933 RP-L6; large subunit ribosomal protein L6 D Spiaf_0547 ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12 D Spiaf_1995 ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9 D Spiaf_0546 ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D Spiaf_0544 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D Spiaf_0665 ribosomal protein L13, bacterial type K02871 RP-L13; large subunit ribosomal protein L13 D Spiaf_0564 ribosomal protein L14, bacterial/organelle K02874 RP-L14; large subunit ribosomal protein L14 D Spiaf_0573 ribosomal protein L15, bacterial/organelle K02876 RP-L15; large subunit ribosomal protein L15 D Spiaf_0561 ribosomal protein L16, bacterial/organelle K02878 RP-L16; large subunit ribosomal protein L16 D Spiaf_0578 ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17 D Spiaf_0570 ribosomal protein L18, bacterial type K02881 RP-L18; large subunit ribosomal protein L18 D Spiaf_1216 ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19 D Spiaf_0812 ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20 D Spiaf_1885 ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21 D Spiaf_0559 ribosomal protein L22, bacterial type K02890 RP-L22; large subunit ribosomal protein L22 D Spiaf_0556 ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D Spiaf_0565 ribosomal protein L24, bacterial/organelle K02895 RP-L24; large subunit ribosomal protein L24 D Spiaf_1876 ribosomal protein L25, Ctc-form K02897 RP-L25; large subunit ribosomal protein L25 D Spiaf_1883 ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27 D Spiaf_2783 ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28 D Spiaf_0562 ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D Spiaf_0572 ribosomal protein L30, bacterial/organelle K02907 RP-L30; large subunit ribosomal protein L30 D Spiaf_1936 ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31 D Spiaf_1695 ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32 D Spiaf_2784 ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D Spiaf_0005 ribosomal protein L34, bacterial type K02914 RP-L34; large subunit ribosomal protein L34 D Spiaf_0813 ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35 D Spiaf_2556 ribosomal protein L36, bacterial type K02919 RP-L36; large subunit ribosomal protein L36 D Spiaf_2142 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Spiaf_2147 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Spiaf_2596 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Spiaf_2594 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Spiaf_2140 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Spiaf_2145 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Spiaf_2593 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Spiaf_2144 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Spiaf_2139 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA C 00970 Aminoacyl-tRNA biosynthesis [PATH:sfc00970] D Spiaf_2595 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Spiaf_0234 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Spiaf_2380 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Spiaf_1344 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Spiaf_1145 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Spiaf_1984 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Spiaf_0315 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Spiaf_2866 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Spiaf_1467 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D Spiaf_1861 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D Spiaf_0330 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D Spiaf_1877 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Spiaf_1897 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Spiaf_2154 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Spiaf_1203 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Spiaf_0838 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Spiaf_1142 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Spiaf_1146 tRNA-His K14226 tRNA-His; tRNA His D Spiaf_2141 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Spiaf_2146 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Spiaf_2686 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Spiaf_1131 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Spiaf_1143 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Spiaf_0341 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Spiaf_0822 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Spiaf_2155 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Spiaf_1144 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Spiaf_0971 tRNA-Met K14230 tRNA-Met; tRNA Met D Spiaf_2015 tRNA-Met K14230 tRNA-Met; tRNA Met D Spiaf_2503 tRNA-Met K14230 tRNA-Met; tRNA Met D Spiaf_0600 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D Spiaf_1345 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Spiaf_0729 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Spiaf_1860 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Spiaf_2867 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Spiaf_2868 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Spiaf_2865 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Spiaf_2864 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Spiaf_0540 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Spiaf_1494 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Spiaf_1909 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Spiaf_0541 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D Spiaf_1495 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D Spiaf_1476 tRNA-Val K14237 tRNA-Val; tRNA Val D Spiaf_1667 tRNA-Val K14237 tRNA-Val; tRNA Val D Spiaf_1924 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Spiaf_2852 amidase, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D Spiaf_2851 glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, B subunit K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D Spiaf_2853 glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, C subunit K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D Spiaf_2062 glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18] D Spiaf_2235 alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Spiaf_1772 putative metal-dependent hydrolase related to alanyl-tRNA synthetase HxxxH domain protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Spiaf_2704 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D Spiaf_2850 aspartyl-tRNA synthetase, archaeal type K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D Spiaf_1184 asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D Spiaf_1923 glycyl-tRNA synthetase, dimeric type K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Spiaf_2602 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Spiaf_1796 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Spiaf_1731 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D Spiaf_1414 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Spiaf_1091 methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D Spiaf_2480 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Spiaf_2640 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Spiaf_2477 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Spiaf_0456 lysyl-tRNA synthetase, archaeal and spirochete K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D Spiaf_1891 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Spiaf_0671 prolyl-tRNA synthetase, family II K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Spiaf_2801 prolyl-tRNA synthetase, family I K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Spiaf_2026 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Spiaf_2659 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Spiaf_2658 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Spiaf_1922 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Spiaf_1733 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] C 03013 Nucleocytoplasmic transport C 03015 mRNA surveillance pathway C 03008 Ribosome biogenesis in eukaryotes B B 09123 Folding, sorting and degradation C 03060 Protein export [PATH:sfc03060] D Spiaf_0574 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Spiaf_0542 preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE D Spiaf_1630 protein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG D Spiaf_0202 protein-export membrane protein, SecD/SecF family K03072 secD; preprotein translocase subunit SecD D Spiaf_0203 protein-export membrane protein, SecD/SecF family K03074 secF; preprotein translocase subunit SecF D Spiaf_0201 preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC D Spiaf_0007 membrane protein insertase, YidC/Oxa1 family, N-terminal domain protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D Spiaf_0781 preprotein translocase, SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D Spiaf_1211 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D Spiaf_2863 Bacterial signal recognition particle RNA K01983 ffs; SRP RNA D Spiaf_1058 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Spiaf_1555 Peptidase S26 K03100 lepB; signal peptidase I [EC:3.4.21.89] D Spiaf_1556 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D Spiaf_0778 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D Spiaf_0231 lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] C 04141 Protein processing in endoplasmic reticulum C 04130 SNARE interactions in vesicular transport C 04120 Ubiquitin mediated proteolysis C 04122 Sulfur relay system D Spiaf_2615 rhodanese-related sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Spiaf_2013 rhodanese-related sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Spiaf_1300 rhodanese-related sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] C 03050 Proteasome C 03018 RNA degradation [PATH:sfc03018] D Spiaf_1721 DNA/RNA helicase, superfamily II K03732 rhlB; ATP-dependent RNA helicase RhlB [EC:5.6.2.7] D Spiaf_0670 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Spiaf_1535 polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D Spiaf_2135 DNA/RNA helicase, superfamily II K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7] D Spiaf_0862 DNA/RNA helicase, superfamily II K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D Spiaf_1888 ATP-dependent DNA helicase, RecQ family K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] D Spiaf_1381 superfamily II DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] D Spiaf_1937 transcription termination factor Rho K03628 rho; transcription termination factor Rho D Spiaf_1976 hypothetical protein K18682 rny; ribonucrease Y [EC:3.1.-.-] D Spiaf_2436 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Spiaf_2077 molecular chaperone K04043 dnaK; molecular chaperone DnaK D Spiaf_1960 chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK D Spiaf_0199 chaperonin GroL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Spiaf_2816 polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] D Spiaf_2762 putative HD superfamily hydrolase K00970 pcnB; poly(A) polymerase [EC:2.7.7.19] D Spiaf_2023 poly(A) polymerase K00970 pcnB; poly(A) polymerase [EC:2.7.7.19] B B 09124 Replication and repair C 03030 DNA replication [PATH:sfc03030] D Spiaf_0831 exonuclease, DNA polymerase III, epsilon subunit family K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Spiaf_2225 DNA-directed DNA polymerase III PolC K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Spiaf_0590 hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Spiaf_2862 DNA polymerase III, subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Spiaf_2663 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Spiaf_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Spiaf_1994 replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D Spiaf_1500 DNA primase, catalytic core K02316 dnaG; DNA primase [EC:2.7.7.101] D Spiaf_1587 single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Spiaf_1998 single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Spiaf_2552 single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Spiaf_0581 ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4] D Spiaf_1206 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D Spiaf_2716 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Spiaf_2216 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03410 Base excision repair [PATH:sfc03410] D Spiaf_1348 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D Spiaf_0462 uracil DNA glycosylase superfamily protein K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] D Spiaf_1732 A/G-specific DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D Spiaf_1080 formamidopyrimidine-DNA glycosylase Fpg K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] D Spiaf_1078 uracil-DNA glycosylase, family 4 K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D Spiaf_1821 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D Spiaf_0352 apurinic endonuclease APN1 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D Spiaf_2716 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Spiaf_1443 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Spiaf_2216 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03420 Nucleotide excision repair [PATH:sfc03420] D Spiaf_1471 transcription-repair coupling factor Mfd K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D Spiaf_1639 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A D Spiaf_0584 excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B D Spiaf_2662 excinuclease ABC, C subunit K03703 uvrC; excinuclease ABC subunit C D Spiaf_0828 DNA/RNA helicase, superfamily I K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Spiaf_0658 DNA/RNA helicase, superfamily I K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Spiaf_2716 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Spiaf_2216 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Spiaf_2723 DNA/RNA helicase, superfamily II K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] C 03430 Mismatch repair [PATH:sfc03430] D Spiaf_1544 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS D Spiaf_2604 mismatch repair ATPase (MutS family) K03555 mutS; DNA mismatch repair protein MutS D Spiaf_1650 mismatch repair ATPase (MutS family) K07456 mutS2; DNA mismatch repair protein MutS2 D Spiaf_1452 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL D Spiaf_0828 DNA/RNA helicase, superfamily I K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Spiaf_0658 DNA/RNA helicase, superfamily I K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Spiaf_1282 exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1] D Spiaf_1680 exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D Spiaf_1681 exonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D Spiaf_1443 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Spiaf_1587 single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Spiaf_1998 single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Spiaf_2552 single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Spiaf_2225 DNA-directed DNA polymerase III PolC K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Spiaf_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Spiaf_0590 hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Spiaf_2862 DNA polymerase III, subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Spiaf_2663 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Spiaf_0831 exonuclease, DNA polymerase III, epsilon subunit family K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Spiaf_2216 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03440 Homologous recombination [PATH:sfc03440] D Spiaf_1443 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Spiaf_1587 single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Spiaf_1998 single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Spiaf_2552 single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Spiaf_0003 recF protein K03629 recF; DNA replication and repair protein RecF D Spiaf_1440 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) D Spiaf_2860 recombination protein RecR K06187 recR; recombination protein RecR D Spiaf_1521 protein RecA K03553 recA; recombination protein RecA D Spiaf_2716 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Spiaf_1552 Holliday junction DNA helicase, RuvA subunit K03550 ruvA; holliday junction DNA helicase RuvA D Spiaf_1551 Holliday junction DNA helicase, RuvB subunit K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D Spiaf_1553 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D Spiaf_2227 RecG-like helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D Spiaf_2225 DNA-directed DNA polymerase III PolC K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Spiaf_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Spiaf_0590 hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Spiaf_2862 DNA polymerase III, subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Spiaf_2663 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Spiaf_0831 exonuclease, DNA polymerase III, epsilon subunit family K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Spiaf_1079 primosomal protein N'' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] C 03450 Non-homologous end-joining C 03460 Fanconi anemia pathway B B 09126 Chromosome C 03082 ATP-dependent chromatin remodeling C 03083 Polycomb repressive complex B B 09125 Information processing in viruses C 03230 Viral genome structure C 03240 Viral replication C 03250 Viral life cycle - HIV-1 [PATH:sfc03250] D Spiaf_2707 peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] C 03260 Virion - Human immunodeficiency virus C 03271 Virion - Rotavirus C 03262 Virion - Coronavirus C 03261 Virion - Influenza virus C 03263 Virion - Enterovirus C 03264 Virion - Flavivirus C 03265 Virion - Ebolavirus and Lyssavirus C 03266 Virion - Herpesvirus C 03268 Virion - Orthopoxvirus C 03267 Virion - Adenovirus C 03259 Virion - Bacteriophages T4 and T7 C 03258 Virion - Bacteriophage lambda # A09130 Environmental Information Processing B B 09131 Membrane transport C 02010 ABC transporters [PATH:sfc02010] D Spiaf_2444 sulfate/thiosulfate-binding protein K02048 cysP; sulfate/thiosulfate transport system substrate-binding protein D Spiaf_2443 sulfate ABC transporter, permease protein CysT K02046 cysU; sulfate/thiosulfate transport system permease protein D Spiaf_2442 sulfate ABC transporter, permease protein K02047 cysW; sulfate/thiosulfate transport system permease protein D Spiaf_2441 sulfate ABC transporter, ATP-binding protein K02045 cysA; sulfate/thiosulfate transport system ATP-binding protein [EC:7.3.2.3] D Spiaf_2364 ABC-type Fe3+ transport system, periplasmic component K02012 afuA; iron(III) transport system substrate-binding protein D Spiaf_2363 ABC-type Fe3+ transport system, permease component K02011 afuB; iron(III) transport system permease protein D Spiaf_2362 ABC-type spermidine/putrescine transport system, ATPase component K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7] D Spiaf_2611 ABC transporter periplasmic binding protein, thiB subfamily K02064 thiB; thiamine transport system substrate-binding protein D Spiaf_2610 ABC-type Fe3+ transport system, permease component K02063 thiP; thiamine transport system permease protein D Spiaf_2609 ABC-type spermidine/putrescine transport system, ATPase component K02062 thiQ; thiamine transport system ATP-binding protein [EC:7.6.2.15] D Spiaf_1170 ABC-type proline/glycine betaine transport system, periplasmic component K02002 proX; glycine betaine/proline transport system substrate-binding protein D Spiaf_1169 ABC-type proline/glycine betaine transport system, permease component K02001 proW; glycine betaine/proline transport system permease protein D Spiaf_1168 glycine betaine/L-proline transport ATP binding subunit K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9] D Spiaf_1095 periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) K05845 opuC; osmoprotectant transport system substrate-binding protein D Spiaf_1096 ABC-type proline/glycine betaine transport system, permease component K05846 opuBD; osmoprotectant transport system permease protein D Spiaf_1098 ABC-type proline/glycine betaine transport system, permease component K05846 opuBD; osmoprotectant transport system permease protein D Spiaf_1097 ABC-type proline/glycine betaine transport system, ATPase component K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9] D Spiaf_2461 ATPase component of ABC-type sugar transporter K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D Spiaf_1151 maltose-binding periplasmic protein K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein D Spiaf_2571 permease component of ABC-type sugar transporter K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D Spiaf_1152 permease component of ABC-type sugar transporter K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D Spiaf_2570 ABC-type maltose transport systems, permease component K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D Spiaf_1153 ABC-type maltose transport systems, permease component K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D Spiaf_2572 ABC-type sugar transport system, periplasmic component K10232 aglE; alpha-glucoside transport system substrate-binding protein D Spiaf_2496 ABC-type sugar transport system, periplasmic component K10232 aglE; alpha-glucoside transport system substrate-binding protein D Spiaf_2495 permease component of ABC-type sugar transporter K10233 aglF; alpha-glucoside transport system permease protein D Spiaf_2494 ABC-type sugar transport system, permease component K10234 aglG; alpha-glucoside transport system permease protein D Spiaf_1331 ABC-type sugar transport system, periplasmic component K10236 thuE; trehalose/maltose transport system substrate-binding protein D Spiaf_1390 ABC-type sugar transport system, periplasmic component K10240 cebE; cellobiose transport system substrate-binding protein D Spiaf_0698 ABC-type sugar transport system, periplasmic component K10240 cebE; cellobiose transport system substrate-binding protein D Spiaf_0700 permease component of ABC-type sugar transporter K10241 cebF; cellobiose transport system permease protein D Spiaf_1391 permease component of ABC-type sugar transporter K10241 cebF; cellobiose transport system permease protein D Spiaf_0699 ABC-type sugar transport system, permease component K10242 cebG; cellobiose transport system permease protein D Spiaf_1392 ABC-type sugar transport system, permease component K10242 cebG; cellobiose transport system permease protein D Spiaf_0504 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein D Spiaf_2032 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein D Spiaf_0502 conserved hypothetical integral membrane protein K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein D Spiaf_2034 ABC-type transport system involved in resistance to organic solvents, permease component K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein D Spiaf_0501 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein D Spiaf_2033 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein D Spiaf_1185 putative ABC-type transport system, periplasmic component/surface lipoprotein K07335 bmpA; basic membrane protein A and related proteins D Spiaf_1189 ABC-type uncharacterized transport system, permease component K23535 nupB; general nucleoside transport system permease protein D Spiaf_1190 putative ABC-type transport system, permease component K23536 nupC; general nucleoside transport system permease protein D Spiaf_1188 ATPase component of uncharacterized ABC-type transporter K23537 nupA; general nucleoside transport system ATP-binding protein D Spiaf_0273 ABC-type xylose transport system, periplasmic component K10543 xylF; D-xylose transport system substrate-binding protein D Spiaf_0274 ABC-type xylose transport system, periplasmic component K10543 xylF; D-xylose transport system substrate-binding protein D Spiaf_0276 ABC-type xylose transport system, permease component K10544 xylH; D-xylose transport system permease protein D Spiaf_0275 ABC-type sugar transport system, ATPase component K10545 xylG; D-xylose transport system ATP-binding protein [EC:7.5.2.10] D Spiaf_0414 ABC-type sugar transport system, periplasmic component K17213 K17213; inositol transport system substrate-binding protein D Spiaf_0413 permease component of ribose/xylose/arabinose/galactoside ABC-type transporters K17214 K17214; inositol transport system permease protein D Spiaf_0412 ABC-type sugar transport system, ATPase component K17215 K17215; inositol transport system ATP-binding protein D Spiaf_0634 phosphate ABC transporter, phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D Spiaf_0636 ABC-type phosphate transport system, periplasmic component K02040 pstS; phosphate transport system substrate-binding protein D Spiaf_0642 ABC-type phosphate transport system, periplasmic component K02040 pstS; phosphate transport system substrate-binding protein D Spiaf_0633 phosphate ABC transporter, permease protein PstC K02037 pstC; phosphate transport system permease protein D Spiaf_0637 ABC-type phosphate transport system, permease component K02037 pstC; phosphate transport system permease protein D Spiaf_0632 phosphate ABC transporter, permease protein PstA K02038 pstA; phosphate transport system permease protein D Spiaf_0638 phosphate ABC transporter, permease protein PstA K02038 pstA; phosphate transport system permease protein D Spiaf_0631 phosphate ABC transporter, ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D Spiaf_0639 ABC-type phosphate transport system, ATPase component K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D Spiaf_2468 ABC-type branched-chain amino acid transport system, periplasmic component K01999 livK; branched-chain amino acid transport system substrate-binding protein D Spiaf_0981 hypothetical protein K03523 bioY; biotin transport system substrate-specific component D Spiaf_2293 ABC-type cobalt transport system, permease component CbiQ K16785 ecfT; energy-coupling factor transport system permease protein D Spiaf_2006 putative ABC-type transport system, periplasmic component/surface lipoprotein K23510 rfuA; riboflavin transport system substrate-binding protein D Spiaf_2008 ABC-type uncharacterized transport system, permease component K23511 rfuC; riboflavin transport system permease protein D Spiaf_2009 putative ABC-type transport system, permease component K23512 rfuD; riboflavin transport system permease protein D Spiaf_2007 ATPase component of uncharacterized ABC-type transporter K23513 rfuB; riboflavin transport system ATP-binding protein D Spiaf_2383 ABC-type multidrug transport system, permease component K09694 nodJ; lipooligosaccharide transport system permease protein D Spiaf_2382 ABC-type multidrug transport system, ATPase component K09695 nodI; lipooligosaccharide transport system ATP-binding protein D Spiaf_1060 ABC-type transport system, involved in lipoprotein release, permease component K09808 lolC_E; lipoprotein-releasing system permease protein D Spiaf_1062 ABC-type transport system, involved in lipoprotein release, permease component K09808 lolC_E; lipoprotein-releasing system permease protein D Spiaf_1061 ABC-type antimicrobial peptide transport system, ATPase component K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-] D Spiaf_1533 putative permease K07091 lptF; lipopolysaccharide export system permease protein D Spiaf_1532 putative permease K11720 lptG; lipopolysaccharide export system permease protein D Spiaf_2672 ABC-type (unclassified) transport system, ATPase component K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5] D Spiaf_1030 hypothetical protein K16905 K16905; fluoroquinolone transport system permease protein D Spiaf_1029 ABC-type multidrug transport system, ATPase component K16907 K16907; fluoroquinolone transport system ATP-binding protein [EC:7.6.2.-] D Spiaf_1946 ABC-type multidrug transport system, ATPase and permease component K18889 mdlA; ATP-binding cassette, subfamily B, multidrug efflux pump D Spiaf_1947 ABC-type multidrug transport system, ATPase and permease component K18890 mdlB; ATP-binding cassette, subfamily B, multidrug efflux pump D Spiaf_0765 ABC-type bacteriocin transporter K20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter C 02060 Phosphotransferase system (PTS) [PATH:sfc02060] D Spiaf_1972 phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] D Spiaf_0520 phosphotransferase system HPr (HPr) family protein K02784 ptsH; phosphocarrier protein HPr D Spiaf_2668 phosphotransferase system HPr (HPr) family protein K02784 ptsH; phosphocarrier protein HPr D Spiaf_0683 phosphotransferase system HPr (HPr) family protein K23993 fruB; multiphosphoryl transfer protein [EC:2.7.3.9 2.7.1.202] D Spiaf_0685 PTS system, fructose-specific, IIB component/PTS system, fructose subfamily, IIC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] D Spiaf_0684 1-phosphofructokinase K00882 fruK; 1-phosphofructokinase [EC:2.7.1.56] D Spiaf_1472 phosphoenolpyruvate-protein phosphotransferase K08484 ptsP; phosphotransferase system, enzyme I, PtsP [EC:2.7.3.9] D Spiaf_0087 phosphotransferase system mannitol/fructose-specifc IIA component (Ntr-type) K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-] D Spiaf_2329 phosphotransferase system mannitol/fructose-specifc IIA component (Ntr-type) K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-] C 03070 Bacterial secretion system [PATH:sfc03070] D Spiaf_2315 outer membrane protein K12340 tolC; outer membrane protein D Spiaf_0099 outer membrane protein K12340 tolC; outer membrane protein D Spiaf_1831 type II secretory pathway, component PulD K02453 gspD; general secretion pathway protein D D Spiaf_1834 general secretion pathway protein G K02456 gspG; general secretion pathway protein G D Spiaf_1832 type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB K02454 gspE; general secretion pathway protein E [EC:7.4.2.8] D Spiaf_0202 protein-export membrane protein, SecD/SecF family K03072 secD; preprotein translocase subunit SecD D Spiaf_0203 protein-export membrane protein, SecD/SecF family K03074 secF; preprotein translocase subunit SecF D Spiaf_0542 preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE D Spiaf_1630 protein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG D Spiaf_0574 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Spiaf_0201 preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC D Spiaf_0007 membrane protein insertase, YidC/Oxa1 family, N-terminal domain protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D Spiaf_0781 preprotein translocase, SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D Spiaf_1058 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Spiaf_1211 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] B B 09132 Signal transduction C 02020 Two-component system [PATH:sfc02020] D Spiaf_0643 signal transduction histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D Spiaf_0644 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB D Spiaf_0634 phosphate ABC transporter, phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D Spiaf_0636 ABC-type phosphate transport system, periplasmic component K02040 pstS; phosphate transport system substrate-binding protein D Spiaf_0642 ABC-type phosphate transport system, periplasmic component K02040 pstS; phosphate transport system substrate-binding protein D Spiaf_2056 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K07662 cpxR; two-component system, OmpR family, response regulator CpxR D Spiaf_0346 periplasmic serine protease, Do/DeqQ family K04771 degP; serine protease Do [EC:3.4.21.107] D Spiaf_1623 periplasmic serine protease, Do/DeqQ family K04771 degP; serine protease Do [EC:3.4.21.107] D Spiaf_1871 trypsin-like serine protease with C-terminal PDZ domain K04771 degP; serine protease Do [EC:3.4.21.107] D Spiaf_1487 flagellin/flagellar hook associated protein K02406 fliC; flagellin D Spiaf_0805 flagellin/flagellar hook associated protein K02406 fliC; flagellin D Spiaf_0806 flagellin/flagellar hook associated protein K02406 fliC; flagellin D Spiaf_2081 RNA polymerase sigma factor, FliA/WhiG family K02405 fliA; RNA polymerase sigma factor FliA D Spiaf_2095 flagellar motor component K02556 motA; chemotaxis protein MotA D Spiaf_0001 chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein D Spiaf_1438 D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D Spiaf_0797 carbon storage regulator CsrA K03563 csrA; carbon storage regulator D Spiaf_0310 P pilus assembly protein, chaperone PapD K07346 fimC; fimbrial chaperone protein D Spiaf_0307 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Spiaf_1199 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Spiaf_2666 histidine kinase,HAMP domain-containing protein,histidine kinase K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3] D Spiaf_2665 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX D Spiaf_2002 Nif-specific regulatory protein K02584 nifA; Nif-specific regulatory protein D Spiaf_1514 transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains K02584 nifA; Nif-specific regulatory protein D Spiaf_2588 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Spiaf_2671 RNA polymerase sigma-54 factor K03092 rpoN; RNA polymerase sigma-54 factor D Spiaf_1868 methylase of chemotaxis methyl-accepting protein K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Spiaf_2677 methylase of chemotaxis methyl-accepting protein K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Spiaf_0215 PAS domain S-box K13924 cheBR; two-component system, chemotaxis family, CheB/CheR fusion protein [EC:2.1.1.80 3.1.1.61] D Spiaf_0140 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_0146 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_0157 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_1044 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_1087 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_0277 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2042 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2060 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2168 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_0417 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2280 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2378 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2433 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2434 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_0727 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2485 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_0823 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2579 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2633 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_1670 chemotaxis signal transduction protein K03408 cheW; purine-binding chemotaxis protein CheW D Spiaf_2133 chemotaxis signal transduction protein K03408 cheW; purine-binding chemotaxis protein CheW D Spiaf_2812 chemotaxis signal transduction protein K03408 cheW; purine-binding chemotaxis protein CheW D Spiaf_1869 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_2075 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_2374 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_1671 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_0148 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_1857 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_1866 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_0607 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_2376 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_2425 response regulator containing a CheY-like receiver domain and a GGDEF domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_1855 response regulator containing a CheY-like receiver domain and a GGDEF domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_2305 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_1668 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_1056 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_1160 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_1867 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Spiaf_2678 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Spiaf_0216 CheY-like receiver domain-containing protein K11443 divK; two-component system, cell cycle response regulator DivK D Spiaf_1865 histidine kinase,Response regulator receiver domain protein,PAS domain-containing protein,histidine kinase K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3] D Spiaf_2240 TRAP-type C4-dicarboxylate transport system, small permease component K11689 dctQ; C4-dicarboxylate transporter, DctQ subunit D Spiaf_2241 TRAP transporter, DctM subunit K11690 dctM; C4-dicarboxylate transporter, DctM subunit D Spiaf_1725 cAMP-binding protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Spiaf_1312 cyclic nucleotide-binding protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Spiaf_0299 cyclic nucleotide-binding protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Spiaf_1844 cyclic nucleotide-binding protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Spiaf_1910 cAMP-binding protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Spiaf_0272 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K07720 yesN; two-component system, response regulator YesN D Spiaf_2315 outer membrane protein K12340 tolC; outer membrane protein D Spiaf_0099 outer membrane protein K12340 tolC; outer membrane protein D Spiaf_2423 protein-tyrosine-phosphatase K25307 wzb; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48] D Spiaf_2462 Fe2+-dicitrate sensor, membrane component K07165 fecR; transmembrane sensor D Spiaf_0354 signal transduction histidine kinase K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3] C 04010 MAPK signaling pathway C 04013 MAPK signaling pathway - fly C 04016 MAPK signaling pathway - plant C 04011 MAPK signaling pathway - yeast C 04012 ErbB signaling pathway C 04014 Ras signaling pathway C 04015 Rap1 signaling pathway C 04310 Wnt signaling pathway C 04330 Notch signaling pathway C 04340 Hedgehog signaling pathway C 04341 Hedgehog signaling pathway - fly C 04350 TGF-beta signaling pathway C 04390 Hippo signaling pathway C 04391 Hippo signaling pathway - fly C 04392 Hippo signaling pathway - multiple species C 04370 VEGF signaling pathway C 04371 Apelin signaling pathway C 04630 JAK-STAT signaling pathway C 04064 NF-kappa B signaling pathway C 04668 TNF signaling pathway C 04066 HIF-1 signaling pathway C 04068 FoxO signaling pathway C 04020 Calcium signaling pathway C 04070 Phosphatidylinositol signaling system C 04072 Phospholipase D signaling pathway C 04071 Sphingolipid signaling pathway C 04024 cAMP signaling pathway C 04022 cGMP-PKG signaling pathway C 04151 PI3K-Akt signaling pathway C 04152 AMPK signaling pathway C 04150 mTOR signaling pathway C 04075 Plant hormone signal transduction B B 09133 Signaling molecules and interaction C 04080 Neuroactive ligand-receptor interaction C 04060 Cytokine-cytokine receptor interaction C 04061 Viral protein interaction with cytokine and cytokine receptor C 04512 ECM-receptor interaction C 04514 Cell adhesion molecules # A09140 Cellular Processes B B 09141 Transport and catabolism C 04144 Endocytosis C 04145 Phagosome C 04142 Lysosome C 04146 Peroxisome C 04140 Autophagy - animal C 04138 Autophagy - yeast C 04136 Autophagy - other C 04137 Mitophagy - animal C 04139 Mitophagy - yeast C 04148 Efferocytosis B B 09143 Cell growth and death C 04110 Cell cycle C 04111 Cell cycle - yeast C 04112 Cell cycle - Caulobacter C 04113 Meiosis - yeast C 04114 Oocyte meiosis C 04210 Apoptosis C 04214 Apoptosis - fly C 04215 Apoptosis - multiple species C 04216 Ferroptosis C 04217 Necroptosis C 04115 p53 signaling pathway C 04218 Cellular senescence B B 09144 Cellular community - eukaryotes C 04510 Focal adhesion C 04520 Adherens junction C 04530 Tight junction C 04540 Gap junction C 04550 Signaling pathways regulating pluripotency of stem cells B B 09145 Cellular community - prokaryotes C 02024 Quorum sensing [PATH:sfc02024] D Spiaf_2551 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D Spiaf_1264 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D Spiaf_2052 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D Spiaf_2393 hypothetical protein K11530 lsrG; (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase [EC:5.3.1.32] D Spiaf_2468 ABC-type branched-chain amino acid transport system, periplasmic component K01999 livK; branched-chain amino acid transport system substrate-binding protein D Spiaf_2453 hypothetical protein K20276 bapA; large repetitive protein D Spiaf_0085 AMP-forming long-chain acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1710 AMP-forming long-chain acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1768 AMP-forming long-chain acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_0924 AMP-forming long-chain acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1302 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1303 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1725 cAMP-binding protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Spiaf_1312 cyclic nucleotide-binding protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Spiaf_0299 cyclic nucleotide-binding protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Spiaf_1844 cyclic nucleotide-binding protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Spiaf_1910 cAMP-binding protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Spiaf_0827 GTP cyclohydrolase II K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25] D Spiaf_1325 riboflavin biosynthesis protein RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D Spiaf_2840 outer membrane protein K18139 oprM; outer membrane protein, multidrug efflux system D Spiaf_0765 ABC-type bacteriocin transporter K20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter D Spiaf_0766 multidrug resistance efflux pump K20345 blpB; membrane fusion protein, peptide pheromone/bacteriocin exporter D Spiaf_2732 ABC-type dipeptide transport system, periplasmic component K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D Spiaf_2074 ABC-type dipeptide transport system, periplasmic component K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D Spiaf_0500 ABC-type dipeptide transport system, periplasmic component K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D Spiaf_2649 ABC-type oligopeptide transport system, periplasmic component K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D Spiaf_2731 ABC-type dipeptide/oligopeptide/nickel transport system, permease component K02033 ABC.PE.P; peptide/nickel transport system permease protein D Spiaf_0499 ABC-type dipeptide/oligopeptide/nickel transport system, permease component K02033 ABC.PE.P; peptide/nickel transport system permease protein D Spiaf_2073 ABC-type dipeptide/oligopeptide/nickel transport system, permease component K02033 ABC.PE.P; peptide/nickel transport system permease protein D Spiaf_2730 ABC-type dipeptide/oligopeptide/nickel transport system, permease component K02034 ABC.PE.P1; peptide/nickel transport system permease protein D Spiaf_0498 ABC-type dipeptide/oligopeptide/nickel transport system, permease component K02034 ABC.PE.P1; peptide/nickel transport system permease protein D Spiaf_2072 ABC-type dipeptide/oligopeptide/nickel transport system, permease component K02034 ABC.PE.P1; peptide/nickel transport system permease protein D Spiaf_2071 oligopeptide/dipeptide ABC transporter, ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D Spiaf_2729 oligopeptide/dipeptide ABC transporter, ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D Spiaf_0496 oligopeptide/dipeptide ABC transporter, ATP-binding protein K02032 ddpF; peptide/nickel transport system ATP-binding protein D Spiaf_0007 membrane protein insertase, YidC/Oxa1 family, N-terminal domain protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D Spiaf_0681 subtilisin-like serine protease K14645 K14645; serine protease [EC:3.4.21.-] D Spiaf_0542 preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE D Spiaf_1630 protein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG D Spiaf_0574 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Spiaf_0201 preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC D Spiaf_0781 preprotein translocase, SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D Spiaf_1058 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Spiaf_1211 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] C 05111 Biofilm formation - Vibrio cholerae C 02025 Biofilm formation - Pseudomonas aeruginosa C 02026 Biofilm formation - Escherichia coli B B 09142 Cell motility C 02030 Bacterial chemotaxis [PATH:sfc02030] D Spiaf_0140 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_0146 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_0157 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_1044 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_1087 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_0277 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2042 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2060 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2168 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_0417 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2280 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2378 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2433 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2434 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_0727 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2485 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_0823 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2579 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2633 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_1869 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_2075 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_2374 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_1671 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_0148 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_1857 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_1670 chemotaxis signal transduction protein K03408 cheW; purine-binding chemotaxis protein CheW D Spiaf_2133 chemotaxis signal transduction protein K03408 cheW; purine-binding chemotaxis protein CheW D Spiaf_2812 chemotaxis signal transduction protein K03408 cheW; purine-binding chemotaxis protein CheW D Spiaf_1866 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_0607 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_2376 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_2425 response regulator containing a CheY-like receiver domain and a GGDEF domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_1855 response regulator containing a CheY-like receiver domain and a GGDEF domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_2305 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_1668 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_1056 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_1160 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_0608 hypothetical protein K03409 cheX; chemotaxis protein CheX D Spiaf_0941 putative inhibitor of MCP methylation, CheC K03409 cheX; chemotaxis protein CheX D Spiaf_1856 putative inhibitor of MCP methylation, CheC K03409 cheX; chemotaxis protein CheX D Spiaf_1669 putative inhibitor of MCP methylation, CheC K03409 cheX; chemotaxis protein CheX D Spiaf_1867 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Spiaf_2678 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Spiaf_0215 PAS domain S-box K13924 cheBR; two-component system, chemotaxis family, CheB/CheR fusion protein [EC:2.1.1.80 3.1.1.61] D Spiaf_2022 chemotaxis protein K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44] D Spiaf_1868 methylase of chemotaxis methyl-accepting protein K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Spiaf_2677 methylase of chemotaxis methyl-accepting protein K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Spiaf_0601 flagellar motor switch protein K02410 fliG; flagellar motor switch protein FliG D Spiaf_2104 flagellar motor switch protein FliG K02410 fliG; flagellar motor switch protein FliG D Spiaf_2092 flagellar motor switch protein FliM K02416 fliM; flagellar motor switch protein FliM D Spiaf_2091 flagellar motor switch protein FliN K02417 fliN; flagellar motor switch protein FliN D Spiaf_2095 flagellar motor component K02556 motA; chemotaxis protein MotA D Spiaf_2094 flagellar motor protein K02557 motB; chemotaxis protein MotB C 02040 Flagellar assembly [PATH:sfc02040] D Spiaf_2106 flagellar hook-basal body complex protein FliE K02408 fliE; flagellar hook-basal body complex protein FliE D Spiaf_2105 flagellar basal-body M-ring protein/flagellar hook-basal body protein FliF K02409 fliF; flagellar M-ring protein FliF D Spiaf_0601 flagellar motor switch protein K02410 fliG; flagellar motor switch protein FliG D Spiaf_2104 flagellar motor switch protein FliG K02410 fliG; flagellar motor switch protein FliG D Spiaf_2103 flagellar biosynthesis/type III secretory pathway protein K02411 fliH; flagellar assembly protein FliH D Spiaf_2102 ATPase FliI/YscN family K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8] D Spiaf_2101 flagellar export protein FliJ K02413 fliJ; flagellar protein FliJ D Spiaf_2093 flagellar basal body-associated protein K02415 fliL; flagellar protein FliL D Spiaf_2092 flagellar motor switch protein FliM K02416 fliM; flagellar motor switch protein FliM D Spiaf_2091 flagellar motor switch protein FliN K02417 fliN; flagellar motor switch protein FliN D Spiaf_2090 flagellar biogenesis protein K02418 fliO; flagellar protein FliO/FliZ D Spiaf_2089 flagellar biosynthetic protein FliP K02419 fliP; flagellar biosynthesis protein FliP D Spiaf_2088 flagellar biosynthetic protein FliQ K02420 fliQ; flagellar biosynthesis protein FliQ D Spiaf_2087 flagellar biosynthetic protein FliR K02421 fliR; flagellar biosynthesis protein FliR D Spiaf_2085 flagellar biosynthesis protein FlhA K02400 flhA; flagellar biosynthesis protein FlhA D Spiaf_2086 flagellar biosynthetic protein FlhB K02401 flhB; flagellar biosynthesis protein FlhB D Spiaf_2108 flagellar basal-body rod protein FlgB K02387 flgB; flagellar basal-body rod protein FlgB D Spiaf_2107 flagellar basal-body rod protein FlgC K02388 flgC; flagellar basal-body rod protein FlgC D Spiaf_2098 flagellar hook capping protein K02389 flgD; flagellar basal-body rod modification protein FlgD D Spiaf_2097 flagellar hook-basal body protein K02390 flgE; flagellar hook protein FlgE D Spiaf_1905 flagellar hook-basal body protein K02391 flgF; flagellar basal-body rod protein FlgF D Spiaf_1904 flagellar basal-body rod protein FlgG K02392 flgG; flagellar basal-body rod protein FlgG D Spiaf_1903 Rod binding protein K02395 flgJ; peptidoglycan hydrolase FlgJ D Spiaf_0794 flagellar hook-associated protein FlgK K02396 flgK; flagellar hook-associated protein 1 D Spiaf_0795 flagellar hook-associated protein 3 K02397 flgL; flagellar hook-associated protein 3 FlgL D Spiaf_1487 flagellin/flagellar hook associated protein K02406 fliC; flagellin D Spiaf_0805 flagellin/flagellar hook associated protein K02406 fliC; flagellin D Spiaf_0806 flagellin/flagellar hook associated protein K02406 fliC; flagellin D Spiaf_0803 flagellar capping protein K02407 fliD; flagellar hook-associated protein 2 D Spiaf_2718 flagellar biosynthetic protein FliS K02422 fliS; flagellar secretion chaperone FliS D Spiaf_2095 flagellar motor component K02556 motA; chemotaxis protein MotA D Spiaf_2094 flagellar motor protein K02557 motB; chemotaxis protein MotB D Spiaf_1902 RNA polymerase sigma factor, sigma-70 family K03086 rpoD; RNA polymerase primary sigma factor D Spiaf_0599 RNA polymerase sigma factor, sigma-70 family K03086 rpoD; RNA polymerase primary sigma factor D Spiaf_1501 RNA polymerase sigma factor, sigma-70 family K03086 rpoD; RNA polymerase primary sigma factor D Spiaf_1858 RNA polymerase sigma factor, sigma-70 family K03086 rpoD; RNA polymerase primary sigma factor D Spiaf_2671 RNA polymerase sigma-54 factor K03092 rpoN; RNA polymerase sigma-54 factor D Spiaf_2081 RNA polymerase sigma factor, FliA/WhiG family K02405 fliA; RNA polymerase sigma factor FliA C 04814 Motor proteins C 04820 Cytoskeleton in muscle cells D Spiaf_0670 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 04810 Regulation of actin cytoskeleton # A09150 Organismal Systems B B 09151 Immune system C 04640 Hematopoietic cell lineage C 04610 Complement and coagulation cascades C 04611 Platelet activation C 04613 Neutrophil extracellular trap formation C 04620 Toll-like receptor signaling pathway C 04624 Toll and Imd signaling pathway C 04621 NOD-like receptor signaling pathway C 04622 RIG-I-like receptor signaling pathway C 04623 Cytosolic DNA-sensing pathway C 04625 C-type lectin receptor signaling pathway C 04650 Natural killer cell mediated cytotoxicity C 04612 Antigen processing and presentation C 04660 T cell receptor signaling pathway C 04658 Th1 and Th2 cell differentiation C 04659 Th17 cell differentiation C 04657 IL-17 signaling pathway C 04662 B cell receptor signaling pathway C 04664 Fc epsilon RI signaling pathway C 04666 Fc gamma R-mediated phagocytosis C 04670 Leukocyte transendothelial migration C 04672 Intestinal immune network for IgA production C 04062 Chemokine signaling pathway B B 09152 Endocrine system C 04911 Insulin secretion C 04910 Insulin signaling pathway C 04922 Glucagon signaling pathway C 04923 Regulation of lipolysis in adipocytes C 04920 Adipocytokine signaling pathway C 03320 PPAR signaling pathway C 04929 GnRH secretion C 04912 GnRH signaling pathway C 04913 Ovarian steroidogenesis C 04915 Estrogen signaling pathway C 04914 Progesterone-mediated oocyte maturation C 04917 Prolactin signaling pathway C 04921 Oxytocin signaling pathway C 04926 Relaxin signaling pathway C 04935 Growth hormone synthesis, secretion and action C 04918 Thyroid hormone synthesis C 04919 Thyroid hormone signaling pathway C 04928 Parathyroid hormone synthesis, secretion and action C 04916 Melanogenesis C 04924 Renin secretion C 04614 Renin-angiotensin system C 04925 Aldosterone synthesis and secretion C 04927 Cortisol synthesis and secretion B B 09153 Circulatory system C 04260 Cardiac muscle contraction C 04261 Adrenergic signaling in cardiomyocytes C 04270 Vascular smooth muscle contraction B B 09154 Digestive system C 04970 Salivary secretion C 04971 Gastric acid secretion C 04972 Pancreatic secretion C 04976 Bile secretion C 04973 Carbohydrate digestion and absorption C 04974 Protein digestion and absorption C 04975 Fat digestion and absorption C 04979 Cholesterol metabolism C 04977 Vitamin digestion and absorption C 04980 Cobalamin transport and metabolism [PATH:sfc04980] D Spiaf_2750 ATP:cob(I)alamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D Spiaf_0490 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] C 04978 Mineral absorption B B 09155 Excretory system C 04962 Vasopressin-regulated water reabsorption C 04960 Aldosterone-regulated sodium reabsorption C 04961 Endocrine and other factor-regulated calcium reabsorption C 04964 Proximal tubule bicarbonate reclamation C 04966 Collecting duct acid secretion B B 09156 Nervous system C 04724 Glutamatergic synapse C 04727 GABAergic synapse C 04725 Cholinergic synapse C 04728 Dopaminergic synapse C 04726 Serotonergic synapse C 04720 Long-term potentiation C 04730 Long-term depression C 04723 Retrograde endocannabinoid signaling C 04721 Synaptic vesicle cycle C 04722 Neurotrophin signaling pathway B B 09157 Sensory system C 04744 Phototransduction C 04745 Phototransduction - fly C 04740 Olfactory transduction C 04742 Taste transduction C 04750 Inflammatory mediator regulation of TRP channels B B 09158 Development and regeneration C 04320 Dorso-ventral axis formation C 04360 Axon guidance C 04361 Axon regeneration C 04380 Osteoclast differentiation B B 09149 Aging C 04211 Longevity regulating pathway C 04212 Longevity regulating pathway - worm C 04213 Longevity regulating pathway - multiple species B B 09159 Environmental adaptation C 04710 Circadian rhythm C 04713 Circadian entrainment C 04711 Circadian rhythm - fly C 04712 Circadian rhythm - plant C 04714 Thermogenesis C 04626 Plant-pathogen interaction # A09160 Human Diseases B B 09161 Cancer: overview C 05200 Pathways in cancer C 05202 Transcriptional misregulation in cancer C 05206 MicroRNAs in cancer C 05205 Proteoglycans in cancer C 05204 Chemical carcinogenesis - DNA adducts C 05207 Chemical carcinogenesis - receptor activation C 05208 Chemical carcinogenesis - reactive oxygen species C 05203 Viral carcinogenesis C 05230 Central carbon metabolism in cancer C 05231 Choline metabolism in cancer C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer B B 09162 Cancer: specific types C 05210 Colorectal cancer C 05212 Pancreatic cancer C 05225 Hepatocellular carcinoma C 05226 Gastric cancer C 05214 Glioma C 05216 Thyroid cancer C 05221 Acute myeloid leukemia C 05220 Chronic myeloid leukemia C 05217 Basal cell carcinoma C 05218 Melanoma C 05211 Renal cell carcinoma C 05219 Bladder cancer C 05215 Prostate cancer C 05213 Endometrial cancer C 05224 Breast cancer C 05222 Small cell lung cancer C 05223 Non-small cell lung cancer B B 09172 Infectious disease: viral C 05166 Human T-cell leukemia virus 1 infection C 05170 Human immunodeficiency virus 1 infection C 05161 Hepatitis B C 05160 Hepatitis C C 05171 Coronavirus disease - COVID-19 C 05164 Influenza A C 05162 Measles C 05168 Herpes simplex virus 1 infection C 05163 Human cytomegalovirus infection C 05167 Kaposi sarcoma-associated herpesvirus infection C 05169 Epstein-Barr virus infection C 05165 Human papillomavirus infection B B 09171 Infectious disease: bacterial C 05110 Vibrio cholerae infection C 05120 Epithelial cell signaling in Helicobacter pylori infection C 05130 Pathogenic Escherichia coli infection C 05132 Salmonella infection C 05131 Shigellosis C 05135 Yersinia infection C 05133 Pertussis C 05134 Legionellosis C 05150 Staphylococcus aureus infection C 05152 Tuberculosis C 05100 Bacterial invasion of epithelial cells B B 09174 Infectious disease: parasitic C 05146 Amoebiasis C 05144 Malaria C 05145 Toxoplasmosis C 05140 Leishmaniasis C 05142 Chagas disease C 05143 African trypanosomiasis B B 09163 Immune disease C 05310 Asthma C 05322 Systemic lupus erythematosus C 05323 Rheumatoid arthritis C 05320 Autoimmune thyroid disease C 05321 Inflammatory bowel disease C 05330 Allograft rejection C 05332 Graft-versus-host disease C 05340 Primary immunodeficiency B B 09164 Neurodegenerative disease C 05010 Alzheimer disease C 05012 Parkinson disease C 05014 Amyotrophic lateral sclerosis C 05016 Huntington disease C 05017 Spinocerebellar ataxia C 05020 Prion disease C 05022 Pathways of neurodegeneration - multiple diseases B B 09165 Substance dependence C 05030 Cocaine addiction C 05031 Amphetamine addiction C 05032 Morphine addiction C 05033 Nicotine addiction C 05034 Alcoholism B B 09166 Cardiovascular disease C 05417 Lipid and atherosclerosis C 05418 Fluid shear stress and atherosclerosis C 05410 Hypertrophic cardiomyopathy C 05412 Arrhythmogenic right ventricular cardiomyopathy C 05414 Dilated cardiomyopathy C 05415 Diabetic cardiomyopathy C 05416 Viral myocarditis B B 09167 Endocrine and metabolic disease C 04930 Type II diabetes mellitus C 04940 Type I diabetes mellitus C 04950 Maturity onset diabetes of the young C 04936 Alcoholic liver disease C 04932 Non-alcoholic fatty liver disease C 04931 Insulin resistance C 04933 AGE-RAGE signaling pathway in diabetic complications C 04934 Cushing syndrome B B 09175 Drug resistance: antimicrobial C 01501 beta-Lactam resistance [PATH:sfc01501] D Spiaf_0792 beta-glucosidase-like glycosyl hydrolase K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52] D Spiaf_1045 beta-glucosidase-like glycosyl hydrolase K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52] D Spiaf_2585 RND family efflux transporter, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Spiaf_2841 RND family efflux transporter, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Spiaf_2840 outer membrane protein K18139 oprM; outer membrane protein, multidrug efflux system D Spiaf_2315 outer membrane protein K12340 tolC; outer membrane protein D Spiaf_0099 outer membrane protein K12340 tolC; outer membrane protein D Spiaf_1914 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Spiaf_0345 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Spiaf_1507 penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] D Spiaf_0777 cell division protein FtsI/penicillin-binding protein 2 K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] C 01502 Vancomycin resistance [PATH:sfc01502] D Spiaf_1716 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D Spiaf_2746 alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D Spiaf_2121 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D Spiaf_2120 phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D Spiaf_0588 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D Spiaf_1438 D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:sfc01503] D Spiaf_2056 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K07662 cpxR; two-component system, OmpR family, response regulator CpxR D Spiaf_1674 N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D Spiaf_0346 periplasmic serine protease, Do/DeqQ family K04771 degP; serine protease Do [EC:3.4.21.107] D Spiaf_1623 periplasmic serine protease, Do/DeqQ family K04771 degP; serine protease Do [EC:3.4.21.107] D Spiaf_1871 trypsin-like serine protease with C-terminal PDZ domain K04771 degP; serine protease Do [EC:3.4.21.107] D Spiaf_2707 peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D Spiaf_2585 RND family efflux transporter, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Spiaf_2841 RND family efflux transporter, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Spiaf_2315 outer membrane protein K12340 tolC; outer membrane protein D Spiaf_0099 outer membrane protein K12340 tolC; outer membrane protein B B 09176 Drug resistance: antineoplastic C 01521 EGFR tyrosine kinase inhibitor resistance C 01524 Platinum drug resistance C 01523 Antifolate resistance C 01522 Endocrine resistance # A09180 Brite Hierarchies B B 09181 Protein families: metabolism C 01000 Enzymes [BR:sfc01000] C 01001 Protein kinases [BR:sfc01001] D Spiaf_2846 protein kinase family protein K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1] D Spiaf_1092 hypothetical protein K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1] D Spiaf_0643 signal transduction histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D Spiaf_2666 histidine kinase,HAMP domain-containing protein,histidine kinase K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3] D Spiaf_1869 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_2075 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_2374 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_1671 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_0148 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_1857 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_1865 histidine kinase,Response regulator receiver domain protein,PAS domain-containing protein,histidine kinase K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3] D Spiaf_0354 signal transduction histidine kinase K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3] D Spiaf_2373 signal transduction histidine kinase K20971 ladS; two-component system, sensor histidine kinase LadS D Spiaf_1103 histidine kinase,Response regulator receiver domain protein,histidine kinase K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3] C 01009 Protein phosphatases and associated proteins [BR:sfc01009] D Spiaf_0010 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D Spiaf_2436 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Spiaf_2634 molecular chaperone of HSP90 family K04079 HSP90A; molecular chaperone HtpG D Spiaf_1783 phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] C 01002 Peptidases and inhibitors [BR:sfc01002] D Spiaf_0231 lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] D Spiaf_1841 type IV leader peptidase K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D Spiaf_1608 GMP synthase (glutamine-hydrolyzing) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D Spiaf_1460 putative glutamine amidotransferase K07010 K07010; putative glutamine amidotransferase D Spiaf_0765 ABC-type bacteriocin transporter K20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter D Spiaf_1953 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D Spiaf_1890 glutamate synthase family protein K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] D Spiaf_2543 glucosamine--fructose-6-phosphate aminotransferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Spiaf_1784 putative intracellular protease/amidase K05520 yhbO; deglycase [EC:3.5.1.124] D Spiaf_2498 DJ-1 family protein K03152 thiJ; protein deglycase [EC:3.5.1.124] D Spiaf_0432 putative metal-dependent membrane protease K07052 K07052; CAAX protease family protein D Spiaf_2210 CAAX amino terminal protease family K07052 K07052; CAAX protease family protein D Spiaf_1132 oligoendopeptidase F K08602 pepF; oligoendopeptidase F [EC:3.4.24.-] D Spiaf_0334 oligoendopeptidase, pepF/M3 family K08602 pepF; oligoendopeptidase F [EC:3.4.24.-] D Spiaf_1438 D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D Spiaf_2560 putative Zn-dependent peptidase, insulinase K06972 PITRM1; presequence protease [EC:3.4.24.-] D Spiaf_2587 putative Zn-dependent peptidase K07263 pqqL; zinc protease [EC:3.4.24.-] D Spiaf_0514 acetylornithine deacetylase/succinyldiaminopimelate desuccinylase-like deacylase K13049 PM20D1; carboxypeptidase PM20D1 [EC:3.4.17.-] D Spiaf_2747 peptidase T K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4] D Spiaf_0314 aminoacyl-histidine dipeptidase K01270 pepD; dipeptidase D [EC:3.4.13.-] D Spiaf_1266 metalloendopeptidase-like membrane protein K21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-] D Spiaf_1293 metalloendopeptidase-like membrane protein K21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-] D Spiaf_1493 methionine aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D Spiaf_1624 methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D Spiaf_0178 Xaa-Pro aminopeptidase K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9] D Spiaf_0476 Xaa-Pro aminopeptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] D Spiaf_2439 leucyl aminopeptidase (aminopeptidase T) K19689 ampS; aminopeptidase [EC:3.4.11.-] D Spiaf_2601 Zn-dependent carboxypeptidase K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19] D Spiaf_1873 ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D Spiaf_2574 ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D Spiaf_1991 RIP metalloprotease RseP K11749 rseP; regulator of sigma E protease [EC:3.4.24.-] D Spiaf_0346 periplasmic serine protease, Do/DeqQ family K04771 degP; serine protease Do [EC:3.4.21.107] D Spiaf_1623 periplasmic serine protease, Do/DeqQ family K04771 degP; serine protease Do [EC:3.4.21.107] D Spiaf_1871 trypsin-like serine protease with C-terminal PDZ domain K04771 degP; serine protease Do [EC:3.4.21.107] D Spiaf_0681 subtilisin-like serine protease K14645 K14645; serine protease [EC:3.4.21.-] D Spiaf_0982 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D Spiaf_1140 ATP-dependent Clp protease, proteolytic subunit ClpP K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] D Spiaf_0459 protease subunit of ATP-dependent protease K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] D Spiaf_1138 ATP-dependent protease La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53] D Spiaf_1439 ATP-dependent protease La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53] D Spiaf_2664 SOS regulatory protein LexA K01356 lexA; repressor LexA [EC:3.4.21.88] D Spiaf_1555 Peptidase S26 K03100 lepB; signal peptidase I [EC:3.4.21.89] D Spiaf_1556 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D Spiaf_0778 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D Spiaf_2778 C-terminal processing peptidase K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] D Spiaf_1204 signal peptide peptidase SppA, 36K type K04773 sppA; protease IV [EC:3.4.21.-] D Spiaf_1281 ClpP class periplasmic serine protease K04773 sppA; protease IV [EC:3.4.21.-] D Spiaf_0083 putative membrane protein K07059 K07059; rhomboid family protein D Spiaf_1577 phage prohead protease, HK97 family K06904 GP4; Escherichia/Staphylococcus phage prohead protease D Spiaf_2110 ATP-dependent protease HslVU, peptidase subunit K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2] D Spiaf_0942 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D Spiaf_0943 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D Spiaf_1799 collagenase-like protease K08303 prtC; U32 family peptidase [EC:3.4.-.-] D Spiaf_1436 collagenase-like protease K08303 prtC; U32 family peptidase [EC:3.4.-.-] D Spiaf_0450 large extracellular alpha-helical protein K06894 yfhM; alpha-2-macroglobulin D Spiaf_1713 HflC protein K04087 hflC; modulator of FtsH protease HflC D Spiaf_1712 HflK protein K04088 hflK; modulator of FtsH protease HflK C 01003 Glycosyltransferases [BR:sfc01003] D Spiaf_0092 glycosyltransferase K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] D Spiaf_0093 glycosyltransferase K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] D Spiaf_0522 glycosyltransferase K00693 GYS; glycogen synthase [EC:2.4.1.11] D Spiaf_0039 glycosyltransferase K16150 K16150; glycogen synthase [EC:2.4.1.11] D Spiaf_0790 glycogen/starch synthase, ADP-glucose type K00703 glgA; starch synthase [EC:2.4.1.21] D Spiaf_0451 membrane carboxypeptidase/penicillin-binding protein PbpC K05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28] D Spiaf_1914 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Spiaf_0345 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Spiaf_2776 teichoic acid biosynthesis protein K05946 tagA; N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase [EC:2.4.1.187] D Spiaf_0067 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D Spiaf_1194 UDP-forming alpha,alpha-trehalose-phosphate synthase K16055 TPS; trehalose 6-phosphate synthase/phosphatase [EC:2.4.1.15 3.1.3.12] C 01005 Lipopolysaccharide biosynthesis proteins [BR:sfc01005] D Spiaf_0067 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:sfc01011] D Spiaf_2765 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D Spiaf_2490 UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D Spiaf_2428 UDP-N-acetylmuramate--alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D Spiaf_1416 UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D Spiaf_1715 UDP-N-acetylmuramyl-tripeptide synthetase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D Spiaf_1716 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D Spiaf_2746 alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D Spiaf_1652 glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3] D Spiaf_2120 phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D Spiaf_0588 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D Spiaf_0596 putative bacitracin resistance protein K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D Spiaf_1530 integral membrane protein MviN K03980 murJ; putative peptidoglycan lipid II flippase D Spiaf_1914 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Spiaf_0345 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Spiaf_0451 membrane carboxypeptidase/penicillin-binding protein PbpC K05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28] D Spiaf_1507 penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] D Spiaf_0777 cell division protein FtsI/penicillin-binding protein 2 K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] D Spiaf_0982 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D Spiaf_1438 D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D Spiaf_1266 metalloendopeptidase-like membrane protein K21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-] D Spiaf_1293 metalloendopeptidase-like membrane protein K21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-] D Spiaf_2734 soluble lytic murein transglycosylase-like protein K08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29] D Spiaf_2526 hypothetical protein K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29] D Spiaf_0455 rare lipoprotein A K03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29] D Spiaf_1674 N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] C 01004 Lipid biosynthesis proteins [BR:sfc01004] D Spiaf_0247 malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D Spiaf_2283 3-oxoacyl-(acyl-carrier-protein) synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D Spiaf_0246 3-oxoacyl-(acyl-carrier-protein) synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D Spiaf_2286 3-oxoacyl-(acyl-carrier-protein) synthase K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41] D Spiaf_0249 beta-ketoacyl-acyl-carrier-protein synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D Spiaf_1413 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spiaf_0248 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spiaf_2282 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spiaf_2772 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spiaf_2284 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase K01716 fabA; 3-hydroxyacyl-[acyl-carrier protein] dehydratase / trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:4.2.1.59 5.3.3.14] D Spiaf_2215 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D Spiaf_2285 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D Spiaf_1423 putative paraquat-inducible protein B K00209 fabV; enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44] D Spiaf_0085 AMP-forming long-chain acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1710 AMP-forming long-chain acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1768 AMP-forming long-chain acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_0924 AMP-forming long-chain acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1302 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1303 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_2505 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D Spiaf_1047 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] C 01008 Polyketide biosynthesis proteins C 01006 Prenyltransferases [BR:sfc01006] D Spiaf_1660 geranylgeranyl pyrophosphate synthase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] D Spiaf_1989 undecaprenyl diphosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D Spiaf_1661 phytoene/squalene synthetase K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32] D Spiaf_1070 tRNA isopentenyltransferase MiaA K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] D Spiaf_1347 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74] C 01007 Amino acid related enzymes [BR:sfc01007] D Spiaf_0456 lysyl-tRNA synthetase, archaeal and spirochete K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D Spiaf_1924 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Spiaf_2062 glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18] D Spiaf_1922 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Spiaf_1733 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D Spiaf_1731 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D Spiaf_1891 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Spiaf_1414 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Spiaf_2477 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Spiaf_2480 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Spiaf_2640 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Spiaf_2704 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D Spiaf_1184 asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D Spiaf_2850 aspartyl-tRNA synthetase, archaeal type K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D Spiaf_2026 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Spiaf_1923 glycyl-tRNA synthetase, dimeric type K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Spiaf_1796 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Spiaf_0671 prolyl-tRNA synthetase, family II K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Spiaf_2801 prolyl-tRNA synthetase, family I K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Spiaf_2602 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Spiaf_2235 alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Spiaf_1772 putative metal-dependent hydrolase related to alanyl-tRNA synthetase HxxxH domain protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Spiaf_2659 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Spiaf_2658 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Spiaf_2136 alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase K00835 avtA; valine--pyruvate aminotransferase [EC:2.6.1.66] D Spiaf_1925 aspartate/tyrosine/aromatic aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D Spiaf_0410 aspartate/tyrosine/aromatic aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D Spiaf_1724 LL-diaminopimelate aminotransferase K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83] D Spiaf_0973 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Spiaf_2562 bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D Spiaf_0192 ornithine/acetylornithine aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D Spiaf_0179 2,4-diaminobutyrate 4-transaminase K00836 ectB; diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76] D Spiaf_2837 diaminobutyrate--2-oxoglutarate aminotransferase K00836 ectB; diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76] D Spiaf_0676 branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Spiaf_2701 phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] C 00199 Cytochrome P450 C 00194 Photosynthesis proteins [BR:sfc00194] D Spiaf_1314 plastocyanin K02638 petE; plastocyanin B B 09182 Protein families: genetic information processing C 03000 Transcription factors [BR:sfc03000] D Spiaf_0875 DNA-methyltransferase Dcm K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Spiaf_0852 hypothetical protein K13653 K13653; AraC family transcriptional regulator D Spiaf_0978 transcriptional regulator K02521 ilvY; LysR family transcriptional regulator, positive regulator for ilvC D Spiaf_2291 transcriptional regulator K03576 metR; LysR family transcriptional regulator, regulator for metE and metH D Spiaf_2695 transcriptional regulator K04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator D Spiaf_2796 transcriptional regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor D Spiaf_0411 transcriptional regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor D Spiaf_2253 transcriptional regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor D Spiaf_2396 transcriptional regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor D Spiaf_1026 transcriptional regulator K05499 cytR; LacI family transcriptional regulator, repressor for deo operon, udp, cdd, tsx, nupC, and nupG D Spiaf_0682 transcriptional regulator K03435 fruR1; LacI family transcriptional regulator, fructose operon transcriptional repressor D Spiaf_1389 transcriptional regulator K02103 araR; GntR family transcriptional regulator, arabinose operon transcriptional repressor D Spiaf_0111 transcriptional regulator K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon D Spiaf_0720 Fe2+/Zn2+ uptake regulation protein K09825 perR; Fur family transcriptional regulator, peroxide stress response regulator D Spiaf_1725 cAMP-binding protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Spiaf_1312 cyclic nucleotide-binding protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Spiaf_0299 cyclic nucleotide-binding protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Spiaf_1844 cyclic nucleotide-binding protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Spiaf_1910 cAMP-binding protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Spiaf_2565 rrf2 family protein, putative transcriptional regulator K13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor D Spiaf_1355 rrf2 family protein, putative transcriptional regulator K17472 cymR; Rrf2 family transcriptional regulator, cysteine metabolism repressor D Spiaf_0267 putative transcriptional regulator K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor D Spiaf_2237 putative transcriptional regulator K21903 cadC; ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor D Spiaf_2029 putative transcriptional regulator K22298 smtB; ArsR family transcriptional regulator, zinc-responsive transcriptional repressor D Spiaf_2365 Mn-dependent transcriptional regulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator D Spiaf_0518 Mn-dependent transcriptional regulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator D Spiaf_2057 Mn-dependent transcriptional regulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator D Spiaf_1318 birA, biotin-(acetyl-CoA-carboxylase) ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] D Spiaf_2819 cytidyltransferase-related enzyme K06211 nadR; HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22] D Spiaf_2702 putative transcriptional regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator D Spiaf_2002 Nif-specific regulatory protein K02584 nifA; Nif-specific regulatory protein D Spiaf_1514 transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains K02584 nifA; Nif-specific regulatory protein D Spiaf_1920 AT-rich DNA-binding protein K01926 rex; redox-sensing transcriptional repressor D Spiaf_2182 putative transcriptional regulator K07729 K07729; putative transcriptional regulator D Spiaf_2187 hypothetical protein K21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor D Spiaf_2869 putative transcriptional regulator K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Spiaf_1915 putative transcriptional regulator K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Spiaf_2650 CarD-like transcriptional regulator K07736 carD; CarD family transcriptional regulator, regulator of rRNA transcription D Spiaf_0195 arginine repressor K03402 argR; transcriptional regulator of arginine metabolism D Spiaf_1251 putative stress-responsive transcriptional regulator K03973 pspC; phage shock protein C D Spiaf_1383 putative transcriptional regulator K07735 algH; putative transcriptional regulator D Spiaf_2528 DnaK suppressor protein K06204 dksA; RNA polymerase-binding transcription factor D Spiaf_2016 transcriptional regulator NrdR K07738 nrdR; transcriptional repressor NrdR D Spiaf_2124 mraZ protein K03925 mraZ; transcriptional regulator MraZ C 03021 Transcription machinery [BR:sfc03021] D Spiaf_2723 DNA/RNA helicase, superfamily II K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] D Spiaf_0577 DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D Spiaf_0548 DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D Spiaf_0549 DNA-directed RNA polymerase, beta'' subunit, predominant form K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D Spiaf_1069 RNA polymerase Rpb6 K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D Spiaf_1902 RNA polymerase sigma factor, sigma-70 family K03086 rpoD; RNA polymerase primary sigma factor D Spiaf_0599 RNA polymerase sigma factor, sigma-70 family K03086 rpoD; RNA polymerase primary sigma factor D Spiaf_1501 RNA polymerase sigma factor, sigma-70 family K03086 rpoD; RNA polymerase primary sigma factor D Spiaf_1858 RNA polymerase sigma factor, sigma-70 family K03086 rpoD; RNA polymerase primary sigma factor D Spiaf_2489 RNA polymerase sigma factor, sigma-70 family K03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily D Spiaf_1464 RNA polymerase sigma factor, sigma-70 family K03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily D Spiaf_2671 RNA polymerase sigma-54 factor K03092 rpoN; RNA polymerase sigma-54 factor D Spiaf_2081 RNA polymerase sigma factor, FliA/WhiG family K02405 fliA; RNA polymerase sigma factor FliA D Spiaf_1541 transcription termination factor NusA K02600 nusA; transcription termination/antitermination protein NusA D Spiaf_1626 transcription antitermination factor NusB K03625 nusB; transcription antitermination protein NusB D Spiaf_2219 transcription antiterminator K02601 nusG; transcription termination/antitermination protein NusG D Spiaf_0543 transcription termination/antitermination factor NusG K02601 nusG; transcription termination/antitermination protein NusG D Spiaf_0453 serine phosphatase RsbU, regulator of sigma subunit K07315 rsbU_P; phosphoserine phosphatase RsbU/P [EC:3.1.3.3] D Spiaf_1287 serine phosphatase RsbU, regulator of sigma subunit K07315 rsbU_P; phosphoserine phosphatase RsbU/P [EC:3.1.3.3] D Spiaf_0952 serine phosphatase RsbU, regulator of sigma subunit K07315 rsbU_P; phosphoserine phosphatase RsbU/P [EC:3.1.3.3] D Spiaf_2713 serine phosphatase RsbU, regulator of sigma subunit K07315 rsbU_P; phosphoserine phosphatase RsbU/P [EC:3.1.3.3] D Spiaf_2646 anti-anti-sigma factor K04749 rsbV; anti-sigma B factor antagonist D Spiaf_1198 anti-anti-sigma factor K04749 rsbV; anti-sigma B factor antagonist D Spiaf_2528 DnaK suppressor protein K06204 dksA; RNA polymerase-binding transcription factor D Spiaf_1937 transcription termination factor Rho K03628 rho; transcription termination factor Rho C 03019 Messenger RNA biogenesis [BR:sfc03019] D Spiaf_1693 ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D Spiaf_1976 hypothetical protein K18682 rny; ribonucrease Y [EC:3.1.-.-] D Spiaf_1721 DNA/RNA helicase, superfamily II K03732 rhlB; ATP-dependent RNA helicase RhlB [EC:5.6.2.7] D Spiaf_2135 DNA/RNA helicase, superfamily II K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7] D Spiaf_0862 DNA/RNA helicase, superfamily II K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D Spiaf_1888 ATP-dependent DNA helicase, RecQ family K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] D Spiaf_1381 superfamily II DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] D Spiaf_0670 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Spiaf_1535 polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D Spiaf_1937 transcription termination factor Rho K03628 rho; transcription termination factor Rho D Spiaf_2436 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Spiaf_2077 molecular chaperone K04043 dnaK; molecular chaperone DnaK D Spiaf_1960 chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK D Spiaf_0199 chaperonin GroL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Spiaf_2816 polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] D Spiaf_2762 putative HD superfamily hydrolase K00970 pcnB; poly(A) polymerase [EC:2.7.7.19] D Spiaf_2023 poly(A) polymerase K00970 pcnB; poly(A) polymerase [EC:2.7.7.19] D Spiaf_0797 carbon storage regulator CsrA K03563 csrA; carbon storage regulator D Spiaf_2027 HrpA-like helicase K03578 hrpA; ATP-dependent RNA helicase HrpA [EC:5.6.2.6] D Spiaf_2623 HrpA-like helicase K03579 hrpB; ATP-dependent RNA helicase HrpB [EC:5.6.2.6] C 03041 Spliceosome C 03011 Ribosome [BR:sfc03011] D Spiaf_1515 ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1 D Spiaf_1986 ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D Spiaf_0560 ribosomal protein S3, bacterial type K02982 RP-S3; small subunit ribosomal protein S3 D Spiaf_1720 ribosomal protein S4, bacterial/organelle type K02986 RP-S4; small subunit ribosomal protein S4 D Spiaf_0571 ribosomal protein S5, bacterial/organelle type K02988 RP-S5; small subunit ribosomal protein S5 D Spiaf_1999 ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6 D Spiaf_0551 ribosomal protein S7, bacterial/organelle K02992 RP-S7; small subunit ribosomal protein S7 D Spiaf_0568 ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D Spiaf_0666 ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D Spiaf_0553 ribosomal protein S10, bacterial/organelle K02946 RP-S10; small subunit ribosomal protein S10 D Spiaf_0576 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D Spiaf_0550 ribosomal protein S12, bacterial/organelle K02950 RP-S12; small subunit ribosomal protein S12 D Spiaf_0575 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D Spiaf_0567 ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D Spiaf_1536 ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D Spiaf_1212 ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16 D Spiaf_0563 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D Spiaf_1997 ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18 D Spiaf_0558 ribosomal protein S19, bacterial/organelle K02965 RP-S19; small subunit ribosomal protein S19 D Spiaf_1944 ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20 D Spiaf_1445 ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21 D Spiaf_0545 ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D Spiaf_0557 ribosomal protein L2, bacterial/organellar K02886 RP-L2; large subunit ribosomal protein L2 D Spiaf_0554 50S ribosomal protein L3, bacterial K02906 RP-L3; large subunit ribosomal protein L3 D Spiaf_0555 50S ribosomal protein L4, bacterial/organelle K02926 RP-L4; large subunit ribosomal protein L4 D Spiaf_0566 ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D Spiaf_0569 ribosomal protein L6, bacterial type K02933 RP-L6; large subunit ribosomal protein L6 D Spiaf_1995 ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9 D Spiaf_0546 ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D Spiaf_0544 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D Spiaf_0547 ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12 D Spiaf_0665 ribosomal protein L13, bacterial type K02871 RP-L13; large subunit ribosomal protein L13 D Spiaf_0564 ribosomal protein L14, bacterial/organelle K02874 RP-L14; large subunit ribosomal protein L14 D Spiaf_0573 ribosomal protein L15, bacterial/organelle K02876 RP-L15; large subunit ribosomal protein L15 D Spiaf_0561 ribosomal protein L16, bacterial/organelle K02878 RP-L16; large subunit ribosomal protein L16 D Spiaf_0578 ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17 D Spiaf_0570 ribosomal protein L18, bacterial type K02881 RP-L18; large subunit ribosomal protein L18 D Spiaf_1216 ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19 D Spiaf_0812 ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20 D Spiaf_1885 ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21 D Spiaf_0559 ribosomal protein L22, bacterial type K02890 RP-L22; large subunit ribosomal protein L22 D Spiaf_0556 ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D Spiaf_0565 ribosomal protein L24, bacterial/organelle K02895 RP-L24; large subunit ribosomal protein L24 D Spiaf_1883 ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27 D Spiaf_2783 ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28 D Spiaf_0562 ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D Spiaf_0572 ribosomal protein L30, bacterial/organelle K02907 RP-L30; large subunit ribosomal protein L30 D Spiaf_1936 ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31 D Spiaf_1695 ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32 D Spiaf_2784 ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D Spiaf_0005 ribosomal protein L34, bacterial type K02914 RP-L34; large subunit ribosomal protein L34 D Spiaf_0813 ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35 D Spiaf_2556 ribosomal protein L36, bacterial type K02919 RP-L36; large subunit ribosomal protein L36 D Spiaf_1876 ribosomal protein L25, Ctc-form K02897 RP-L25; large subunit ribosomal protein L25 D Spiaf_2593 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Spiaf_2144 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Spiaf_2139 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Spiaf_2142 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Spiaf_2147 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Spiaf_2596 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Spiaf_2594 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Spiaf_2140 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Spiaf_2145 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA C 03009 Ribosome biogenesis [BR:sfc03009] D Spiaf_1693 ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D Spiaf_0829 tRNA/rRNA cytosine-C5-methylase K21970 NSUN4; 5-methylcytosine rRNA methyltransferase NSUN4 [EC:2.1.1.-] D Spiaf_0458 small GTP-binding protein domain protein K03595 era; GTPase D Spiaf_1882 Obg family GTPase CgtA K03979 obgE; GTPase [EC:3.6.5.-] D Spiaf_2528 DnaK suppressor protein K06204 dksA; RNA polymerase-binding transcription factor D Spiaf_1541 transcription termination factor NusA K02600 nusA; transcription termination/antitermination protein NusA D Spiaf_1626 transcription antitermination factor NusB K03625 nusB; transcription antitermination protein NusB D Spiaf_2219 transcription antiterminator K02601 nusG; transcription termination/antitermination protein NusG D Spiaf_0543 transcription termination/antitermination factor NusG K02601 nusG; transcription termination/antitermination protein NusG D Spiaf_2206 dimethyladenosine transferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D Spiaf_2228 N6-adenine-specific methylase K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171] D Spiaf_2777 RNA methyltransferase, RsmE family K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193] D Spiaf_2041 RNA methyltransferase, RsmE family K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193] D Spiaf_2737 16S rRNA (guanine(527)-N(7))-methyltransferase GidB K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D Spiaf_2123 S-adenosyl-methyltransferase MraW K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199] D Spiaf_0221 putative S-adenosylmethionine-dependent methyltransferase, YraL family K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198] D Spiaf_1974 putative rRNA methylase K06442 tlyA; 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227] D Spiaf_1957 rRNA methylase, putative, group 3 K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185] D Spiaf_0082 23S rRNA methylase K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166] D Spiaf_0724 16S RNA G1207 methylase RsmC K11391 rlmG; 23S rRNA (guanine1835-N2)-methyltransferase [EC:2.1.1.174] D Spiaf_1478 putative N6-adenine-specific DNA methylase K25137 rlmL; 23S rRNA (guanine2445-N2)-methyltransferase [EC:2.1.1.173] D Spiaf_2430 23S rRNA m2A2503 methyltransferase K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192] D Spiaf_1919 SAM-dependent methyltransferase, tRNA(uracil-5)-methyltransferase K03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190] D Spiaf_1294 23S rRNA (uracil-5-)-methyltransferase RumA K03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190] D Spiaf_1517 pseudouridine synthase family protein K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22] D Spiaf_1656 pseudouridine synthase, RluA family K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D Spiaf_1214 16S rRNA processing protein RimM K02860 rimM; 16S rRNA processing protein RimM D Spiaf_0862 DNA/RNA helicase, superfamily II K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D Spiaf_1651 ribosome small subunit-dependent GTPase A K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D Spiaf_2164 ribosome small subunit-dependent GTPase A K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D Spiaf_1971 ribosome-associated GTPase EngA K03977 engA; GTPase D Spiaf_2454 GTP-binding protein HflX K03665 hflX; GTPase D Spiaf_1697 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D Spiaf_1825 (p)ppGpp synthetase, RelA/SpoT family K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D Spiaf_1539 ribosome-binding factor A K02834 rbfA; ribosome-binding factor A D Spiaf_1542 hypothetical protein K09748 rimP; ribosome maturation factor RimP D Spiaf_1879 iojap-like ribosome-associated protein K09710 ybeB; ribosome-associated protein D Spiaf_1636 metalloprotein, YbeY/UPF0054 family K07042 ybeY; probable rRNA maturation factor D Spiaf_1164 putative RNA-binding protein, YhbY family K07574 yhbY; RNA-binding protein D Spiaf_2670 ribosome-associated protein Y (PSrp-1) K05808 hpf; ribosome hibernation promoting factor D Spiaf_0355 GTP-binding protein YchF K06942 ychF; ribosome-binding ATPase C 03016 Transfer RNA biogenesis [BR:sfc03016] D Spiaf_1425 ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11] D Spiaf_1486 tRNA nucleotidyltransferase/poly(A) polymerase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-] D Spiaf_1924 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Spiaf_0671 prolyl-tRNA synthetase, family II K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Spiaf_2801 prolyl-tRNA synthetase, family I K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Spiaf_2477 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Spiaf_2640 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Spiaf_1414 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Spiaf_2062 glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18] D Spiaf_1891 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Spiaf_2704 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D Spiaf_2235 alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Spiaf_1772 putative metal-dependent hydrolase related to alanyl-tRNA synthetase HxxxH domain protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Spiaf_1184 asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D Spiaf_1923 glycyl-tRNA synthetase, dimeric type K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Spiaf_2602 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Spiaf_1796 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Spiaf_1731 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D Spiaf_2480 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Spiaf_2026 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Spiaf_2659 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Spiaf_2658 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Spiaf_1922 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Spiaf_1733 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D Spiaf_1523 D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96] D Spiaf_2700 HIT family hydrolase, diadenosine tetraphosphate hydrolase K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D Spiaf_1473 tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33] D Spiaf_1077 pseudouridylate synthase I K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12] D Spiaf_1538 tRNA pseudouridine 55 synthase K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25] D Spiaf_0440 putative tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase with PP-loop ATPase domain K21027 TRMU; tRNA-5-taurinomethyluridine 2-sulfurtransferase [EC:2.8.1.14] D Spiaf_1697 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D Spiaf_1070 tRNA isopentenyltransferase MiaA K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] D Spiaf_2739 tRNA modification GTPase TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-] D Spiaf_2738 glucose-inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D Spiaf_0967 inositol monophosphatase/fructose-1,6-bisphosphatase family protein K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7] D Spiaf_0006 ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5] D Spiaf_2167 ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5] D Spiaf_0263 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58] D Spiaf_2519 ATP-binding cassette protein, ChvD family K06020 ettA; energy-dependent translational throttle protein EttA D Spiaf_0456 lysyl-tRNA synthetase, archaeal and spirochete K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D Spiaf_2850 aspartyl-tRNA synthetase, archaeal type K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D Spiaf_0445 tRNA-dihydrouridine synthase K05539 dusA; tRNA-dihydrouridine synthase A [EC:1.-.-.-] D Spiaf_1197 tRNA-dihydrouridine synthase K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-] D Spiaf_1250 radical SAM methylthiotransferase, MiaB/RimO family K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3] D Spiaf_1225 radical SAM methylthiotransferase, MiaB/RimO family K18707 mtaB; threonylcarbamoyladenosine tRNA methylthiotransferase MtaB [EC:2.8.4.5] D Spiaf_1215 tRNA (guanine-N1)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D Spiaf_1292 rRNA methylase K00556 trmH; tRNA (guanosine-2'-O-)-methyltransferase [EC:2.1.1.34] D Spiaf_1827 putative rRNA methylase SpoU family K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207] D Spiaf_1295 putative N6-adenine-specific DNA methylase K16318 trm14; tRNA (guanine6-N2)-methyltransferase [EC:2.1.1.256] D Spiaf_0224 rRNA methylase K03437 spoU; RNA methyltransferase, TrmH family D Spiaf_0340 putative ATPase of the PP-loop superfamily implicated in cell cycle control K14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA D Spiaf_2134 glycine/D-amino acid oxidase, deaminating K15461 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-] D Spiaf_1550 S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17] D Spiaf_0419 7-cyano-7-deazaguanine reductase K09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13] D Spiaf_1349 uncharacterized Fe-S protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6] D Spiaf_1531 tRNA-guanine transglycosylase, queuosine-34-forming K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29] D Spiaf_1874 tRNA(Ile)-lysidine synthetase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19] D Spiaf_0798 universal bacterial protein YeaZ K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB D Spiaf_1900 putative glycoprotease GCP K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234] D Spiaf_0799 ATPase, YjeE family K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE D Spiaf_2632 dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase D Spiaf_1535 polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D Spiaf_0435 putative nucleic acid-binding protein, contains PIN domain K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-] D Spiaf_0045 putative nucleic acid-binding protein, contains PIN domain K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-] C 03012 Translation factors [BR:sfc03012] D Spiaf_1540 translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2 D Spiaf_0814 translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3 D Spiaf_1820 ATPase component of ABC transporters with duplicated ATPase domain K06158 ABCF3; ATP-binding cassette, subfamily F, member 3 D Spiaf_0344 ATPase component of ABC transporters with duplicated ATPase domain K06158 ABCF3; ATP-binding cassette, subfamily F, member 3 D Spiaf_1987 translation elongation factor Ts K02357 tsf; elongation factor Ts D Spiaf_0552 translation elongation factor TU K02358 tuf; elongation factor Tu D Spiaf_2652 translation elongation factor EF-G K02355 fusA; elongation factor G D Spiaf_1474 small GTP-binding protein domain protein K02355 fusA; elongation factor G D Spiaf_1475 translation elongation factor EF-G K02355 fusA; elongation factor G D Spiaf_1823 peptide chain release factor 1 K02835 prfA; peptide chain release factor 1 D Spiaf_1988 ribosome recycling factor K02838 frr; ribosome recycling factor D Spiaf_1824 protein-(glutamine-N5) methyltransferase, release factor-specific K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297] D Spiaf_1875 peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29] D Spiaf_2859 peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29] D Spiaf_2529 translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1 D Spiaf_2564 translation elongation factor P K02356 efp; elongation factor P D Spiaf_2563 lysyl-tRNA synthetase (class II) K04568 epmA; elongation factor P--(R)-beta-lysine ligase [EC:6.3.1.-] D Spiaf_1055 peptide chain release factor 2 K02836 prfB; peptide chain release factor 2 D Spiaf_1603 peptide chain release factor 3 K02837 prfC; peptide chain release factor 3 C 03110 Chaperones and folding catalysts [BR:sfc03110] D Spiaf_1929 ATP-dependent Clp protease ATP-binding subunit clpA K03694 clpA; ATP-dependent Clp protease ATP-binding subunit ClpA D Spiaf_2012 ATP-dependent chaperone ClpB K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB D Spiaf_1064 ATPase with chaperone activity, ATP-binding subunit K03696 clpC; ATP-dependent Clp protease ATP-binding subunit ClpC D Spiaf_1139 endopeptidase Clp ATP-binding regulatory subunit ClpX K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX D Spiaf_2109 ATP-dependent protease HslVU, ATPase subunit K03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU D Spiaf_2634 molecular chaperone of HSP90 family K04079 HSP90A; molecular chaperone HtpG D Spiaf_2077 molecular chaperone K04043 dnaK; molecular chaperone DnaK D Spiaf_1960 chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK D Spiaf_0199 chaperonin GroL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Spiaf_1959 chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ D Spiaf_2766 DnaJ-class molecular chaperone with C-terminal Zn finger domain K05801 djlA; DnaJ like chaperone protein D Spiaf_0687 disulfide bond chaperone K04083 hslO; molecular chaperone Hsp33 D Spiaf_1961 molecular chaperone GrpE (heat shock protein) K03687 GRPE; molecular chaperone GrpE D Spiaf_0467 molecular chaperone (small heat shock protein) K13993 HSP20; HSP20 family protein D Spiaf_0468 molecular chaperone (small heat shock protein) K13993 HSP20; HSP20 family protein D Spiaf_2680 molecular chaperone (small heat shock protein) K04081 ibpB; molecular chaperone IbpB D Spiaf_0598 Co-chaperonin GroES K04078 groES; chaperonin GroES D Spiaf_0346 periplasmic serine protease, Do/DeqQ family K04771 degP; serine protease Do [EC:3.4.21.107] D Spiaf_1623 periplasmic serine protease, Do/DeqQ family K04771 degP; serine protease Do [EC:3.4.21.107] D Spiaf_1871 trypsin-like serine protease with C-terminal PDZ domain K04771 degP; serine protease Do [EC:3.4.21.107] D Spiaf_1873 ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D Spiaf_2574 ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D Spiaf_0310 P pilus assembly protein, chaperone PapD K07346 fimC; fimbrial chaperone protein D Spiaf_0681 subtilisin-like serine protease K14645 K14645; serine protease [EC:3.4.21.-] D Spiaf_2707 peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D Spiaf_1862 parvulin-like peptidyl-prolyl isomerase K03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8] D Spiaf_0523 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8] D Spiaf_1627 parvulin-like peptidyl-prolyl isomerase K03771 surA; peptidyl-prolyl cis-trans isomerase SurA [EC:5.2.1.8] D Spiaf_2545 thioredoxin K03671 TXN; thioredoxin D Spiaf_2638 thioredoxin K03671 TXN; thioredoxin D Spiaf_0854 Glutaredoxin-like protein, YruB-family K03676 grxC; glutaredoxin 3 C 04131 Membrane trafficking [BR:sfc04131] D Spiaf_0335 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D Spiaf_1633 glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D Spiaf_1156 fructose-2,6-bisphosphatase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D Spiaf_2001 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Spiaf_2634 molecular chaperone of HSP90 family K04079 HSP90A; molecular chaperone HtpG C 04121 Ubiquitin system C 03051 Proteasome [BR:sfc03051] D Spiaf_2634 molecular chaperone of HSP90 family K04079 HSP90A; molecular chaperone HtpG C 03032 DNA replication proteins [BR:sfc03032] D Spiaf_0581 ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4] D Spiaf_0875 DNA-methyltransferase Dcm K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Spiaf_1943 bacterial nucleoid DNA-binding protein K04764 ihfA; integration host factor subunit alpha D Spiaf_0001 chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein D Spiaf_1994 replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D Spiaf_1500 DNA primase, catalytic core K02316 dnaG; DNA primase [EC:2.7.7.101] D Spiaf_1587 single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Spiaf_1998 single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Spiaf_2552 single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Spiaf_2225 DNA-directed DNA polymerase III PolC K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Spiaf_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Spiaf_2663 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Spiaf_0831 exonuclease, DNA polymerase III, epsilon subunit family K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Spiaf_0590 hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Spiaf_2862 DNA polymerase III, subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Spiaf_1206 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D Spiaf_2716 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Spiaf_2216 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Spiaf_2873 DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D Spiaf_2874 type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D Spiaf_2055 type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D Spiaf_2054 type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D Spiaf_2553 DNA topoisomerase I, bacterial K03168 topA; DNA topoisomerase I [EC:5.6.2.1] C 03036 Chromosome and associated proteins [BR:sfc03036] D Spiaf_0875 DNA-methyltransferase Dcm K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Spiaf_1693 ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D Spiaf_1943 bacterial nucleoid DNA-binding protein K04764 ihfA; integration host factor subunit alpha D Spiaf_0001 chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein D Spiaf_0240 DNA-binding ferritin-like protein (oxidative damage protectant) K04047 dps; starvation-inducible DNA-binding protein D Spiaf_1207 RecF/RecN/SMC N-terminal domain-containing protein K03529 smc; chromosome segregation protein D Spiaf_1519 hypothetical protein K05896 scpA; segregation and condensation protein A D Spiaf_1518 segregation and condensation protein B K06024 scpB; segregation and condensation protein B D Spiaf_2117 cell division protein FtsA K03590 ftsA; cell division protein FtsA D Spiaf_0777 cell division protein FtsI/penicillin-binding protein 2 K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] D Spiaf_2733 DNA segregation ATPase, FtsK/SpoIIIE family K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family D Spiaf_2122 hypothetical protein K03586 ftsL; cell division protein FtsL D Spiaf_2118 cell division septal protein K03589 ftsQ; cell division protein FtsQ D Spiaf_2119 cell division protein FtsW K03588 ftsW; cell division protein FtsW D Spiaf_2116 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D Spiaf_1674 N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D Spiaf_2585 RND family efflux transporter, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Spiaf_2841 RND family efflux transporter, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Spiaf_1504 cell shape determining protein, MreB/Mrl family K03569 mreB; rod shape-determining protein MreB and related proteins D Spiaf_1505 rod shape-determining protein MreC K03570 mreC; rod shape-determining protein MreC D Spiaf_1506 cell shape-determining protein K03571 mreD; rod shape-determining protein MreD D Spiaf_1508 rod shape-determining protein RodA K05837 rodA; rod shape determining protein RodA D Spiaf_2870 ATPase involved in chromosome partitioning K03496 parA; chromosome partitioning protein D Spiaf_1360 ATPase involved in chromosome partitioning K03496 parA; chromosome partitioning protein D Spiaf_2869 putative transcriptional regulator K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Spiaf_1915 putative transcriptional regulator K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Spiaf_2055 type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D Spiaf_2054 type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D Spiaf_2738 glucose-inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D Spiaf_2737 16S rRNA (guanine(527)-N(7))-methyltransferase GidB K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D Spiaf_2111 site-specific recombinase XerD K04763 xerD; integrase/recombinase XerD D Spiaf_2115 tyrosine recombinase XerD K04763 xerD; integrase/recombinase XerD D Spiaf_1376 site-specific recombinase XerD K04763 xerD; integrase/recombinase XerD C 03400 DNA repair and recombination proteins [BR:sfc03400] D Spiaf_2457 O-6-methylguanine DNA methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D Spiaf_1158 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D Spiaf_0462 uracil DNA glycosylase superfamily protein K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] D Spiaf_1732 A/G-specific DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D Spiaf_1348 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D Spiaf_2723 DNA/RNA helicase, superfamily II K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] D Spiaf_1465 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Spiaf_0786 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Spiaf_1534 deoxyuridine 5'-triphosphate nucleotidohydrolase Dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D Spiaf_0903 deoxyribodipyrimidine photolyase-related protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13] D Spiaf_1078 uracil-DNA glycosylase, family 4 K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D Spiaf_1080 formamidopyrimidine-DNA glycosylase Fpg K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] D Spiaf_1821 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D Spiaf_0352 apurinic endonuclease APN1 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D Spiaf_1443 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Spiaf_2216 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Spiaf_2716 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Spiaf_1639 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A D Spiaf_0584 excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B D Spiaf_2662 excinuclease ABC, C subunit K03703 uvrC; excinuclease ABC subunit C D Spiaf_0828 DNA/RNA helicase, superfamily I K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Spiaf_0658 DNA/RNA helicase, superfamily I K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Spiaf_0548 DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D Spiaf_0549 DNA-directed RNA polymerase, beta'' subunit, predominant form K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D Spiaf_0577 DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D Spiaf_1069 RNA polymerase Rpb6 K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D Spiaf_1471 transcription-repair coupling factor Mfd K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D Spiaf_1544 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS D Spiaf_2604 mismatch repair ATPase (MutS family) K03555 mutS; DNA mismatch repair protein MutS D Spiaf_1650 mismatch repair ATPase (MutS family) K07456 mutS2; DNA mismatch repair protein MutS2 D Spiaf_1452 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL D Spiaf_1282 exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1] D Spiaf_1680 exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D Spiaf_1681 exonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D Spiaf_2225 DNA-directed DNA polymerase III PolC K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Spiaf_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Spiaf_2663 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Spiaf_0831 exonuclease, DNA polymerase III, epsilon subunit family K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Spiaf_0590 hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Spiaf_2862 DNA polymerase III, subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Spiaf_1587 single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Spiaf_1998 single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Spiaf_2552 single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Spiaf_0874 DNA mismatch endonuclease Vsr K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-] D Spiaf_1521 protein RecA K03553 recA; recombination protein RecA D Spiaf_1552 Holliday junction DNA helicase, RuvA subunit K03550 ruvA; holliday junction DNA helicase RuvA D Spiaf_1551 Holliday junction DNA helicase, RuvB subunit K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D Spiaf_1553 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D Spiaf_1079 primosomal protein N'' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] D Spiaf_1083 DNA repair exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11 D Spiaf_2613 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms D Spiaf_0003 recF protein K03629 recF; DNA replication and repair protein RecF D Spiaf_2227 RecG-like helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D Spiaf_1440 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) D Spiaf_2860 recombination protein RecR K06187 recR; recombination protein RecR D Spiaf_2130 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N) D Spiaf_0403 CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1 D Spiaf_2873 DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D Spiaf_2874 type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D Spiaf_2553 DNA topoisomerase I, bacterial K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D Spiaf_1943 bacterial nucleoid DNA-binding protein K04764 ihfA; integration host factor subunit alpha D Spiaf_1888 ATP-dependent DNA helicase, RecQ family K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] D Spiaf_1381 superfamily II DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] D Spiaf_1718 nucleotidyltransferase/DNA polymerase involved in DNA repair K02346 dinB; DNA polymerase IV [EC:2.7.7.7] D Spiaf_2664 SOS regulatory protein LexA K01356 lexA; repressor LexA [EC:3.4.21.88] D Spiaf_0613 DNA polymerase elongation subunit (family B) K02336 polB; DNA polymerase II [EC:2.7.7.7] D Spiaf_1692 DNA-directed DNA polymerase III PolC K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7] D Spiaf_0667 hypothetical protein K03565 recX; regulatory protein D Spiaf_0597 DNA helicase, Rad3 K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D Spiaf_0747 ribonucleoside-diphosphate reductase, alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Spiaf_0746 ribonucleotide reductase, beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D Spiaf_1135 exopolyphosphatase-like enzyme K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] C 03029 Mitochondrial biogenesis [BR:sfc03029] D Spiaf_1540 translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2 D Spiaf_0814 translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3 D Spiaf_1987 translation elongation factor Ts K02357 tsf; elongation factor Ts D Spiaf_0552 translation elongation factor TU K02358 tuf; elongation factor Tu D Spiaf_2652 translation elongation factor EF-G K02355 fusA; elongation factor G D Spiaf_1474 small GTP-binding protein domain protein K02355 fusA; elongation factor G D Spiaf_1475 translation elongation factor EF-G K02355 fusA; elongation factor G D Spiaf_0458 small GTP-binding protein domain protein K03595 era; GTPase D Spiaf_1922 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Spiaf_2640 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Spiaf_2704 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D Spiaf_1923 glycyl-tRNA synthetase, dimeric type K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Spiaf_1891 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Spiaf_2852 amidase, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D Spiaf_2851 glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, B subunit K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D Spiaf_2853 glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, C subunit K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D Spiaf_0829 tRNA/rRNA cytosine-C5-methylase K21970 NSUN4; 5-methylcytosine rRNA methyltransferase NSUN4 [EC:2.1.1.-] D Spiaf_1587 single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Spiaf_1998 single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Spiaf_2552 single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Spiaf_1546 Beta-barrel assembly machine subunit BamA K07277 SAM50; outer membrane protein insertion porin family D Spiaf_2077 molecular chaperone K04043 dnaK; molecular chaperone DnaK D Spiaf_1960 chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK D Spiaf_1961 molecular chaperone GrpE (heat shock protein) K03687 GRPE; molecular chaperone GrpE D Spiaf_0199 chaperonin GroL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Spiaf_0598 Co-chaperonin GroES K04078 groES; chaperonin GroES D Spiaf_1959 chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ D Spiaf_0007 membrane protein insertase, YidC/Oxa1 family, N-terminal domain protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D Spiaf_2634 molecular chaperone of HSP90 family K04079 HSP90A; molecular chaperone HtpG B B 09183 Protein families: signaling and cellular processes C 02000 Transporters [BR:sfc02000] D Spiaf_1946 ABC-type multidrug transport system, ATPase and permease component K18889 mdlA; ATP-binding cassette, subfamily B, multidrug efflux pump D Spiaf_1947 ABC-type multidrug transport system, ATPase and permease component K18890 mdlB; ATP-binding cassette, subfamily B, multidrug efflux pump D Spiaf_0055 ABC-type bacteriocin/lantibiotic exporter with N-terminal double-glycine peptidase domain K24846 pglK; ATP-binding cassette, subfamily B, bacterial PglK [EC:7.5.2.-] D Spiaf_2197 ABC-type multidrug transport system, ATPase and permease component K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial D Spiaf_2198 ABC-type multidrug transport system, ATPase and permease component K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial D Spiaf_2160 ABC-type multidrug transport system, ATPase and permease component K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial D Spiaf_0765 ABC-type bacteriocin transporter K20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter D Spiaf_1755 ATPase component of ABC transporters with duplicated ATPase domain K15738 uup; ABC transport system ATP-binding/permease protein D Spiaf_2444 sulfate/thiosulfate-binding protein K02048 cysP; sulfate/thiosulfate transport system substrate-binding protein D Spiaf_2443 sulfate ABC transporter, permease protein CysT K02046 cysU; sulfate/thiosulfate transport system permease protein D Spiaf_2442 sulfate ABC transporter, permease protein K02047 cysW; sulfate/thiosulfate transport system permease protein D Spiaf_2441 sulfate ABC transporter, ATP-binding protein K02045 cysA; sulfate/thiosulfate transport system ATP-binding protein [EC:7.3.2.3] D Spiaf_2364 ABC-type Fe3+ transport system, periplasmic component K02012 afuA; iron(III) transport system substrate-binding protein D Spiaf_2363 ABC-type Fe3+ transport system, permease component K02011 afuB; iron(III) transport system permease protein D Spiaf_2362 ABC-type spermidine/putrescine transport system, ATPase component K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7] D Spiaf_2611 ABC transporter periplasmic binding protein, thiB subfamily K02064 thiB; thiamine transport system substrate-binding protein D Spiaf_2610 ABC-type Fe3+ transport system, permease component K02063 thiP; thiamine transport system permease protein D Spiaf_2609 ABC-type spermidine/putrescine transport system, ATPase component K02062 thiQ; thiamine transport system ATP-binding protein [EC:7.6.2.15] D Spiaf_1170 ABC-type proline/glycine betaine transport system, periplasmic component K02002 proX; glycine betaine/proline transport system substrate-binding protein D Spiaf_1169 ABC-type proline/glycine betaine transport system, permease component K02001 proW; glycine betaine/proline transport system permease protein D Spiaf_1168 glycine betaine/L-proline transport ATP binding subunit K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9] D Spiaf_1095 periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) K05845 opuC; osmoprotectant transport system substrate-binding protein D Spiaf_1096 ABC-type proline/glycine betaine transport system, permease component K05846 opuBD; osmoprotectant transport system permease protein D Spiaf_1098 ABC-type proline/glycine betaine transport system, permease component K05846 opuBD; osmoprotectant transport system permease protein D Spiaf_1097 ABC-type proline/glycine betaine transport system, ATPase component K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9] D Spiaf_2403 hypothetical protein K02051 ABC.SN.S; NitT/TauT family transport system substrate-binding protein D Spiaf_1845 ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component K02051 ABC.SN.S; NitT/TauT family transport system substrate-binding protein D Spiaf_2808 ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component K02051 ABC.SN.S; NitT/TauT family transport system substrate-binding protein D Spiaf_1847 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component K02050 ABC.SN.P; NitT/TauT family transport system permease protein D Spiaf_1846 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component K02049 ABC.SN.A; NitT/TauT family transport system ATP-binding protein D Spiaf_2461 ATPase component of ABC-type sugar transporter K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D Spiaf_2252 ABC-type sugar transport system, periplasmic component K25086 musE; maltose transport system substrate-binding protein D Spiaf_2251 permease component of ABC-type sugar transporter K25087 musF; maltose transport system permease protein D Spiaf_2250 ABC-type sugar transport system, permease component K25088 musG; maltose transport system permease protein D Spiaf_1151 maltose-binding periplasmic protein K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein D Spiaf_2571 permease component of ABC-type sugar transporter K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D Spiaf_1152 permease component of ABC-type sugar transporter K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D Spiaf_2570 ABC-type maltose transport systems, permease component K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D Spiaf_1153 ABC-type maltose transport systems, permease component K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D Spiaf_2572 ABC-type sugar transport system, periplasmic component K10232 aglE; alpha-glucoside transport system substrate-binding protein D Spiaf_2496 ABC-type sugar transport system, periplasmic component K10232 aglE; alpha-glucoside transport system substrate-binding protein D Spiaf_2495 permease component of ABC-type sugar transporter K10233 aglF; alpha-glucoside transport system permease protein D Spiaf_2494 ABC-type sugar transport system, permease component K10234 aglG; alpha-glucoside transport system permease protein D Spiaf_1331 ABC-type sugar transport system, periplasmic component K10236 thuE; trehalose/maltose transport system substrate-binding protein D Spiaf_1390 ABC-type sugar transport system, periplasmic component K10240 cebE; cellobiose transport system substrate-binding protein D Spiaf_0698 ABC-type sugar transport system, periplasmic component K10240 cebE; cellobiose transport system substrate-binding protein D Spiaf_0700 permease component of ABC-type sugar transporter K10241 cebF; cellobiose transport system permease protein D Spiaf_1391 permease component of ABC-type sugar transporter K10241 cebF; cellobiose transport system permease protein D Spiaf_0699 ABC-type sugar transport system, permease component K10242 cebG; cellobiose transport system permease protein D Spiaf_1392 ABC-type sugar transport system, permease component K10242 cebG; cellobiose transport system permease protein D Spiaf_0273 ABC-type xylose transport system, periplasmic component K10543 xylF; D-xylose transport system substrate-binding protein D Spiaf_0274 ABC-type xylose transport system, periplasmic component K10543 xylF; D-xylose transport system substrate-binding protein D Spiaf_0276 ABC-type xylose transport system, permease component K10544 xylH; D-xylose transport system permease protein D Spiaf_0275 ABC-type sugar transport system, ATPase component K10545 xylG; D-xylose transport system ATP-binding protein [EC:7.5.2.10] D Spiaf_0121 ABC-type sugar transport system, periplasmic component K25067 fcsSBP; fucose transport system substrate-binding protein D Spiaf_0122 permease component of ABC-type sugar transporter K25068 K25068; fucose transport system permease protein D Spiaf_0123 ABC-type sugar transport system, permease component K25069 K25069; fucose transport system permease protein D Spiaf_0414 ABC-type sugar transport system, periplasmic component K17213 K17213; inositol transport system substrate-binding protein D Spiaf_0413 permease component of ribose/xylose/arabinose/galactoside ABC-type transporters K17214 K17214; inositol transport system permease protein D Spiaf_0412 ABC-type sugar transport system, ATPase component K17215 K17215; inositol transport system ATP-binding protein D Spiaf_1185 putative ABC-type transport system, periplasmic component/surface lipoprotein K07335 bmpA; basic membrane protein A and related proteins D Spiaf_1189 ABC-type uncharacterized transport system, permease component K23535 nupB; general nucleoside transport system permease protein D Spiaf_1190 putative ABC-type transport system, permease component K23536 nupC; general nucleoside transport system permease protein D Spiaf_1188 ATPase component of uncharacterized ABC-type transporter K23537 nupA; general nucleoside transport system ATP-binding protein D Spiaf_2006 putative ABC-type transport system, periplasmic component/surface lipoprotein K23510 rfuA; riboflavin transport system substrate-binding protein D Spiaf_2008 ABC-type uncharacterized transport system, permease component K23511 rfuC; riboflavin transport system permease protein D Spiaf_2009 putative ABC-type transport system, permease component K23512 rfuD; riboflavin transport system permease protein D Spiaf_2007 ATPase component of uncharacterized ABC-type transporter K23513 rfuB; riboflavin transport system ATP-binding protein D Spiaf_2559 ABC-type uncharacterized transport system, permease component K02069 STAR2; UDP-glucose/iron transport system permease protein D Spiaf_0504 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein D Spiaf_2032 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein D Spiaf_0502 conserved hypothetical integral membrane protein K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein D Spiaf_2034 ABC-type transport system involved in resistance to organic solvents, permease component K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein D Spiaf_0501 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein D Spiaf_2033 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein D Spiaf_0503 ABC-type uncharacterized transport system, auxiliary component K18480 linN; cholesterol transport system auxiliary component D Spiaf_0949 ABC-type sugar transport system, periplasmic component K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein D Spiaf_2515 ABC-type sugar transport system, periplasmic component K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein D Spiaf_2795 ABC-type sugar transport system, periplasmic component K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein D Spiaf_0948 permease component of ABC-type sugar transporter K02025 ABC.MS.P; multiple sugar transport system permease protein D Spiaf_2794 permease component of ABC-type sugar transporter K02025 ABC.MS.P; multiple sugar transport system permease protein D Spiaf_2516 permease component of ABC-type sugar transporter K02025 ABC.MS.P; multiple sugar transport system permease protein D Spiaf_0947 ABC-type sugar transport system, permease component K02026 ABC.MS.P1; multiple sugar transport system permease protein D Spiaf_2793 ABC-type sugar transport system, permease component K02026 ABC.MS.P1; multiple sugar transport system permease protein D Spiaf_2517 ABC-type sugar transport system, permease component K02026 ABC.MS.P1; multiple sugar transport system permease protein D Spiaf_0634 phosphate ABC transporter, phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D Spiaf_0636 ABC-type phosphate transport system, periplasmic component K02040 pstS; phosphate transport system substrate-binding protein D Spiaf_0642 ABC-type phosphate transport system, periplasmic component K02040 pstS; phosphate transport system substrate-binding protein D Spiaf_0633 phosphate ABC transporter, permease protein PstC K02037 pstC; phosphate transport system permease protein D Spiaf_0637 ABC-type phosphate transport system, permease component K02037 pstC; phosphate transport system permease protein D Spiaf_0632 phosphate ABC transporter, permease protein PstA K02038 pstA; phosphate transport system permease protein D Spiaf_0638 phosphate ABC transporter, permease protein PstA K02038 pstA; phosphate transport system permease protein D Spiaf_0631 phosphate ABC transporter, ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D Spiaf_0639 ABC-type phosphate transport system, ATPase component K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D Spiaf_2468 ABC-type branched-chain amino acid transport system, periplasmic component K01999 livK; branched-chain amino acid transport system substrate-binding protein D Spiaf_0292 ABC-type uncharacterized transport system, periplasmic component K01989 K01989; putative tryptophan/tyrosine transport system substrate-binding protein D Spiaf_0293 ABC-type uncharacterized transport system, permease component K05832 K05832; putative tryptophan/tyrosine transport system permease protein D Spiaf_0294 ABC-type uncharacterized transport system, ATPase component K05833 K05833; putative tryptophan/tyrosine transport system ATP-binding protein D Spiaf_0847 periplasmic component of amino acid ABC-type transporter/signal transduction system K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein D Spiaf_0714 periplasmic component of amino acid ABC-type transporter/signal transduction system K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein D Spiaf_0848 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family K02029 ABC.PA.P; polar amino acid transport system permease protein D Spiaf_0715 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family K02029 ABC.PA.P; polar amino acid transport system permease protein D Spiaf_0716 ABC-type polar amino acid transport system, ATPase component K02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1] D Spiaf_0849 ABC-type polar amino acid transport system, ATPase component K02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1] D Spiaf_2732 ABC-type dipeptide transport system, periplasmic component K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D Spiaf_2074 ABC-type dipeptide transport system, periplasmic component K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D Spiaf_0500 ABC-type dipeptide transport system, periplasmic component K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D Spiaf_2649 ABC-type oligopeptide transport system, periplasmic component K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D Spiaf_2731 ABC-type dipeptide/oligopeptide/nickel transport system, permease component K02033 ABC.PE.P; peptide/nickel transport system permease protein D Spiaf_0499 ABC-type dipeptide/oligopeptide/nickel transport system, permease component K02033 ABC.PE.P; peptide/nickel transport system permease protein D Spiaf_2073 ABC-type dipeptide/oligopeptide/nickel transport system, permease component K02033 ABC.PE.P; peptide/nickel transport system permease protein D Spiaf_2730 ABC-type dipeptide/oligopeptide/nickel transport system, permease component K02034 ABC.PE.P1; peptide/nickel transport system permease protein D Spiaf_0498 ABC-type dipeptide/oligopeptide/nickel transport system, permease component K02034 ABC.PE.P1; peptide/nickel transport system permease protein D Spiaf_2072 ABC-type dipeptide/oligopeptide/nickel transport system, permease component K02034 ABC.PE.P1; peptide/nickel transport system permease protein D Spiaf_2071 oligopeptide/dipeptide ABC transporter, ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D Spiaf_2729 oligopeptide/dipeptide ABC transporter, ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D Spiaf_0496 oligopeptide/dipeptide ABC transporter, ATP-binding protein K02032 ddpF; peptide/nickel transport system ATP-binding protein D Spiaf_0754 ATPase component of Mn/Zn ABC-type transporter K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-] D Spiaf_2246 ABC-type Fe3+-hydroxamate transport system, periplasmic component K25034 btuF; cobalamin transport system substrate-binding protein D Spiaf_2247 ABC-type Fe3+-siderophore transport system, permease component K25027 btuC; cobalamin transport system permease protein D Spiaf_2248 ABC-type cobalamin/Fe3+-siderophore transport system, ATPase component K25028 btuD; cobalamin transport system ATP-binding protein [EC:7.6.2.8] D Spiaf_0965 ABC-type metal ion transport system, periplasmic component/surface adhesin K09818 ABC.MN.S; manganese/iron transport system substrate-binding protein D Spiaf_0610 ABC-type Mn2+/Zn2+ transport system, permease component K09819 ABC.MN.P; manganese/iron transport system permease protein D Spiaf_2368 ABC-type Mn2+/Zn2+ transport system, permease component K09819 ABC.MN.P; manganese/iron transport system permease protein D Spiaf_0611 ATPase component of Mn/Zn ABC-type transporter K09820 ABC.MN.A; manganese/iron transport system ATP-binding protein D Spiaf_0981 hypothetical protein K03523 bioY; biotin transport system substrate-specific component D Spiaf_2296 YKOF-like protein K24620 ykoF; energy-coupling factor transport system substrate-specific component D Spiaf_2293 ABC-type cobalt transport system, permease component CbiQ K16785 ecfT; energy-coupling factor transport system permease protein D Spiaf_2294 ATPase component of various ABC-type transport systems with duplicated ATPase domain K01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D Spiaf_2295 putative membrane protein K16925 ykoE; energy-coupling factor transport system permease protein D Spiaf_2370 ABC-type metal ion transport system, periplasmic component/surface adhesin K02077 ABC.ZM.S; zinc/manganese transport system substrate-binding protein D Spiaf_1533 putative permease K07091 lptF; lipopolysaccharide export system permease protein D Spiaf_1532 putative permease K11720 lptG; lipopolysaccharide export system permease protein D Spiaf_2672 ABC-type (unclassified) transport system, ATPase component K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5] D Spiaf_2383 ABC-type multidrug transport system, permease component K09694 nodJ; lipooligosaccharide transport system permease protein D Spiaf_2382 ABC-type multidrug transport system, ATPase component K09695 nodI; lipooligosaccharide transport system ATP-binding protein D Spiaf_1427 hypothetical protein K25151 gldF; gliding motility-associated transport system permease protein D Spiaf_1426 ABC-type multidrug transport system, ATPase component K25152 gldA; gliding motility-associated transport system ATP-binding protein D Spiaf_1428 ABC-type uncharacterized transport system involved in gliding motility, auxiliary component K25153 gldG; gliding motility-associatede transport system auxiliary component D Spiaf_1001 ABC-type multidrug transport system, permease component K25180 ybhR; drug efflux transport system permease protein D Spiaf_1000 ABC-type multidrug transport system, permease component K25181 ybhS; drug efflux transport system permease protein D Spiaf_0999 ABC-type multidrug transport system, ATPase component K25182 ybhF; drug efflux transport system ATP-binding protein D Spiaf_0426 ABC-type multidrug transport system, permease component K25142 lnrN; linearmycin/streptolysin S transport system permease protein D Spiaf_0425 ABC-type multidrug transport system, permease component K25143 lnrM; linearmycin/streptolysin S transport system permease protein D Spiaf_0424 ABC-type multidrug transport system, ATPase component K25144 lnrL; linearmycin/streptolysin S transport system ATP-binding protein D Spiaf_1030 hypothetical protein K16905 K16905; fluoroquinolone transport system permease protein D Spiaf_1029 ABC-type multidrug transport system, ATPase component K16907 K16907; fluoroquinolone transport system ATP-binding protein [EC:7.6.2.-] D Spiaf_1060 ABC-type transport system, involved in lipoprotein release, permease component K09808 lolC_E; lipoprotein-releasing system permease protein D Spiaf_1062 ABC-type transport system, involved in lipoprotein release, permease component K09808 lolC_E; lipoprotein-releasing system permease protein D Spiaf_1061 ABC-type antimicrobial peptide transport system, ATPase component K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-] D Spiaf_1259 ABC-type multidrug transport system, permease component K01992 ABC-2.P; ABC-2 type transport system permease protein D Spiaf_0987 ABC-type multidrug transport system, ATPase component K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Spiaf_0997 ABC-type multidrug transport system, ATPase component K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Spiaf_1260 ABC-type multidrug transport system, ATPase component K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Spiaf_0188 ABC-type transport system, involved in lipoprotein release, permease component K02004 ABC.CD.P; putative ABC transport system permease protein D Spiaf_2312 ABC-type antimicrobial peptide transport system, permease component K02004 ABC.CD.P; putative ABC transport system permease protein D Spiaf_0171 ABC-type transport system, involved in lipoprotein release, permease component K02004 ABC.CD.P; putative ABC transport system permease protein D Spiaf_0172 ABC-type transport system, involved in lipoprotein release, permease component K02004 ABC.CD.P; putative ABC transport system permease protein D Spiaf_0065 ABC-type transport system, involved in lipoprotein release, permease component K02004 ABC.CD.P; putative ABC transport system permease protein D Spiaf_0066 ABC-type transport system, involved in lipoprotein release, permease component K02004 ABC.CD.P; putative ABC transport system permease protein D Spiaf_1779 ABC-type antimicrobial peptide transport system, ATPase component K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D Spiaf_0186 ABC-type antimicrobial peptide transport system, ATPase component K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D Spiaf_2313 ABC-type antimicrobial peptide transport system, ATPase component K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D Spiaf_0173 ABC-type antimicrobial peptide transport system, ATPase component K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D Spiaf_1701 FeS assembly ATPase SufC K09013 sufC; Fe-S cluster assembly ATP-binding protein D Spiaf_0925 NhaP-type Na+(K+)/H+ antiporter K23994 SLC9B1_2; solute carrier family 9B (sodium/hydrogen exchanger), member 1/2 D Spiaf_0132 anion transporter K14445 SLC13A2_3_5; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5 D Spiaf_2681 putative efflux protein, MATE family K26939 norM; MATE family, multidrug efflux pump D Spiaf_2790 putative efflux protein, MATE family K26937 dinF; MATE family, multidrug efflux pump D Spiaf_2581 putative efflux protein, MATE family K26937 dinF; MATE family, multidrug efflux pump D Spiaf_0356 putative efflux protein, MATE family K26937 dinF; MATE family, multidrug efflux pump D Spiaf_2435 cyanate permease K08177 oxlT; MFS transporter, OFA family, oxalate/formate antiporter D Spiaf_0928 Major Facilitator Superfamily transporter K08177 oxlT; MFS transporter, OFA family, oxalate/formate antiporter D Spiaf_1972 phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] D Spiaf_1472 phosphoenolpyruvate-protein phosphotransferase K08484 ptsP; phosphotransferase system, enzyme I, PtsP [EC:2.7.3.9] D Spiaf_0520 phosphotransferase system HPr (HPr) family protein K02784 ptsH; phosphocarrier protein HPr D Spiaf_2668 phosphotransferase system HPr (HPr) family protein K02784 ptsH; phosphocarrier protein HPr D Spiaf_0683 phosphotransferase system HPr (HPr) family protein K23993 fruB; multiphosphoryl transfer protein [EC:2.7.3.9 2.7.1.202] D Spiaf_0685 PTS system, fructose-specific, IIB component/PTS system, fructose subfamily, IIC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] D Spiaf_0087 phosphotransferase system mannitol/fructose-specifc IIA component (Ntr-type) K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-] D Spiaf_2329 phosphotransferase system mannitol/fructose-specifc IIA component (Ntr-type) K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-] D Spiaf_2624 Kef-type K+ ransport system, predicted NAD-binding component K10716 kch; voltage-gated potassium channel D Spiaf_0281 K+ transport system, NAD-binding component K10716 kch; voltage-gated potassium channel D Spiaf_1726 TrkA family protein K10716 kch; voltage-gated potassium channel D Spiaf_0609 ammonium transporter K03320 amt; ammonium transporter, Amt family D Spiaf_2003 ammonium transporter K03320 amt; ammonium transporter, Amt family D Spiaf_2848 von Willebrand factor type A-like protein K07114 yfbK; Ca-activated chloride channel homolog D Spiaf_2533 Mg-chelatase subunit ChlD K07114 yfbK; Ca-activated chloride channel homolog D Spiaf_2534 Mg-chelatase subunit ChlD K07114 yfbK; Ca-activated chloride channel homolog D Spiaf_2698 small-conductance mechanosensitive channel K22044 ybiO; moderate conductance mechanosensitive channel D Spiaf_2335 small-conductance mechanosensitive channel K16053 ybdG; miniconductance mechanosensitive channel D Spiaf_2578 Mg2+ transporter MgtE K06213 mgtE; magnesium transporter D Spiaf_0421 Mg2+ transporter MgtE K06213 mgtE; magnesium transporter D Spiaf_2095 flagellar motor component K02556 motA; chemotaxis protein MotA D Spiaf_2094 flagellar motor protein K02557 motB; chemotaxis protein MotB D Spiaf_2340 biopolymer transport protein K03561 exbB; biopolymer transport protein ExbB D Spiaf_1966 biopolymer transport protein K03561 exbB; biopolymer transport protein ExbB D Spiaf_1965 biopolymer transport protein K03559 exbD; biopolymer transport protein ExbD D Spiaf_2338 biopolymer transport protein K03559 exbD; biopolymer transport protein ExbD D Spiaf_2339 biopolymer transport protein K03559 exbD; biopolymer transport protein ExbD D Spiaf_2270 CBS domain-containing protein K16302 CNNM; metal transporter CNNM D Spiaf_2639 CBS domain-containing protein K03699 tlyC; magnesium and cobalt exporter, CNNM family D Spiaf_1773 outer membrane protein/peptidoglycan-associated (lipo)protein K16191 K16191; peptidoglycan-binding protein ArfA D Spiaf_1741 outer membrane protein/peptidoglycan-associated (lipo)protein K03286 TC.OOP; OmpA-OmpF porin, OOP family D Spiaf_0750 outer membrane cobalamin receptor protein K16092 btuB; vitamin B12 transporter D Spiaf_2315 outer membrane protein K12340 tolC; outer membrane protein D Spiaf_0099 outer membrane protein K12340 tolC; outer membrane protein D Spiaf_2840 outer membrane protein K18139 oprM; outer membrane protein, multidrug efflux system D Spiaf_1546 Beta-barrel assembly machine subunit BamA K07277 SAM50; outer membrane protein insertion porin family D Spiaf_2255 outer membrane protein/protective antigen OMA87 K07278 tamA; translocation and assembly module TamA D Spiaf_1547 hypothetical protein K09800 tamB; translocation and assembly module TamB D Spiaf_2673 hypothetical protein K09774 lptA; lipopolysaccharide export system protein LptA D Spiaf_1635 CBS domain-containing protein K06189 corC; hemolysin (HlyC) family protein D Spiaf_0134 hypothetical protein K16210 togT; oligogalacturonide transporter D Spiaf_1771 Na+/melibiose symporter-like transporter K16210 togT; oligogalacturonide transporter D Spiaf_1412 putative permease, DMT superfamily K03298 TC.DME; drug/metabolite transporter, DME family D Spiaf_1604 putative permease K07084 yuiF; putative amino acid transporter D Spiaf_1605 L-lactate transport K03303 lutP; lactate permease D Spiaf_1477 K+dependent Na+ exchanger related-protein K07301 yrbG; cation:H+ antiporter D Spiaf_0927 sodium/proline symporter K11928 putP; sodium/proline symporter D Spiaf_2159 Na+/glutamate symporter K03312 gltS; glutamate:Na+ symporter, ESS family D Spiaf_0757 Kef-type K+ transport system, membrane component K26730 napA; Na+:H+ antiporter D Spiaf_1766 Kef-type K+ transport system, membrane component K26730 napA; Na+:H+ antiporter D Spiaf_1112 Kef-type K+ transport system, membrane component K26730 napA; Na+:H+ antiporter D Spiaf_0516 Trk-type K+ transport system, membrane component K03498 trkH; trk/ktr system potassium uptake protein D Spiaf_0515 K+ transport system, NAD-binding component K03499 trkA; trk/ktr system potassium uptake protein D Spiaf_1326 uracil-xanthine permease K02824 uraA; uracil permease D Spiaf_1308 permease K06901 pbuG; adenine/guanine/hypoxanthine permease D Spiaf_0525 chloride channel protein EriC K03281 clcA; chloride channel protein, CIC family D Spiaf_2576 chromate transport protein ChrA K07240 chrA; chromate transporter D Spiaf_2577 chromate transport protein ChrA K07240 chrA; chromate transporter D Spiaf_2307 sulfate permease-like transporter, MFS superfamily K03321 TC.SULP; sulfate permease, SulP family D Spiaf_2240 TRAP-type C4-dicarboxylate transport system, small permease component K11689 dctQ; C4-dicarboxylate transporter, DctQ subunit D Spiaf_2241 TRAP transporter, DctM subunit K11690 dctM; C4-dicarboxylate transporter, DctM subunit D Spiaf_0641 Na+/phosphate symporter K03324 yjbB; phosphate:Na+ symporter D Spiaf_0269 Na/Pi-cotransporter K03324 yjbB; phosphate:Na+ symporter D Spiaf_0624 arsenical-resistance protein K03325 ACR3; arsenite transporter D Spiaf_2325 multisubunit Na+/H+ antiporter, MnhB subunit K05566 mnhB; multicomponent Na+:H+ antiporter subunit B D Spiaf_2326 multisubunit Na+/H+ antiporter, MnhC subunit K05567 mnhC; multicomponent Na+:H+ antiporter subunit C D Spiaf_2327 formate hydrogenlyase subunit 3/multisubunit Na+/H+ antiporter, MnhD subunit K05568 mnhD; multicomponent Na+:H+ antiporter subunit D D Spiaf_2328 formate hydrogenlyase subunit 3/multisubunit Na+/H+ antiporter, MnhD subunit K05568 mnhD; multicomponent Na+:H+ antiporter subunit D D Spiaf_2321 multisubunit Na+/H+ antiporter, MnhE subunit K05569 mnhE; multicomponent Na+:H+ antiporter subunit E D Spiaf_2322 multisubunit Na+/H+ antiporter, MnhF subunit K05570 mnhF; multicomponent Na+:H+ antiporter subunit F D Spiaf_2323 monovalent cation/proton antiporter, MnhG/PhaG subunit K05571 mnhG; multicomponent Na+:H+ antiporter subunit G D Spiaf_1530 integral membrane protein MviN K03980 murJ; putative peptidoglycan lipid II flippase D Spiaf_1722 putative permease K24180 mleP; malate permease and related proteins D Spiaf_2192 putative branched-chain amino acid permease (azaleucine resistance) K26605 azlC; branched chain amino acid efflux pump D Spiaf_2193 putative membrane protein K26606 azlD; branched chain amino acid efflux pump D Spiaf_1482 conserved hypothetical integral membrane protein K09125 yhhQ; queuosine precursor transporter D Spiaf_0420 conserved hypothetical integral membrane protein K09125 yhhQ; queuosine precursor transporter D Spiaf_0920 membrane protein, MarC family K05595 marC; multiple antibiotic resistance protein D Spiaf_2119 cell division protein FtsW K03588 ftsW; cell division protein FtsW D Spiaf_0535 ABC-type uncharacterized transport system, permease component K08970 rcnA; nickel/cobalt transporter (NicO) family protein D Spiaf_0752 TonB family protein K03832 tonB; periplasmic protein TonB D Spiaf_2337 TonB family protein K03832 tonB; periplasmic protein TonB D Spiaf_1964 TonB family protein K03832 tonB; periplasmic protein TonB D Spiaf_0076 vacuolar-type H(+)-translocating pyrophosphatase K15987 hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:7.2.3.1] D Spiaf_1708 vacuolar-type H(+)-translocating pyrophosphatase K15987 hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:7.2.3.1] D Spiaf_0509 cytochrome c biogenesis protein K06196 ccdA; cytochrome c-type biogenesis protein D Spiaf_2585 RND family efflux transporter, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Spiaf_2841 RND family efflux transporter, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Spiaf_0766 multidrug resistance efflux pump K20345 blpB; membrane fusion protein, peptide pheromone/bacteriocin exporter D Spiaf_1176 small GTP-binding protein domain protein K04759 feoB; ferrous iron transport protein B D Spiaf_0694 putative membrane protein K07507 mgtC; putative Mg2+ transporter-C (MgtC) family protein D Spiaf_0422 putative membrane protein K07507 mgtC; putative Mg2+ transporter-C (MgtC) family protein C 02044 Secretion system [BR:sfc02044] D Spiaf_2315 outer membrane protein K12340 tolC; outer membrane protein D Spiaf_0099 outer membrane protein K12340 tolC; outer membrane protein D Spiaf_1831 type II secretory pathway, component PulD K02453 gspD; general secretion pathway protein D D Spiaf_1832 type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB K02454 gspE; general secretion pathway protein E [EC:7.4.2.8] D Spiaf_1834 general secretion pathway protein G K02456 gspG; general secretion pathway protein G D Spiaf_1841 type IV leader peptidase K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D Spiaf_1434 hypothetical protein K08086 fimV; pilus assembly protein FimV D Spiaf_2226 YGGT family protein K02221 yggT; YggT family protein D Spiaf_2207 ComEC/Rec2-related protein K02238 comEC; competence protein ComEC D Spiaf_1372 putative hydrolase (metallo-beta-lactamase superfamily) K02238 comEC; competence protein ComEC D Spiaf_0725 putative hydrolase (metallo-beta-lactamase superfamily) K02238 comEC; competence protein ComEC D Spiaf_1993 Late competence development protein ComFB K02241 comFB; competence protein ComFB D Spiaf_1457 Late competence development protein ComFB K02241 comFB; competence protein ComFB D Spiaf_2085 flagellar biosynthesis protein FlhA K02400 flhA; flagellar biosynthesis protein FlhA D Spiaf_2086 flagellar biosynthetic protein FlhB K02401 flhB; flagellar biosynthesis protein FlhB D Spiaf_1218 uncharacterized protein, cytoplasmic domain of flagellar protein FhlB like protein K04061 flhB2; flagellar biosynthesis protein D Spiaf_2105 flagellar basal-body M-ring protein/flagellar hook-basal body protein FliF K02409 fliF; flagellar M-ring protein FliF D Spiaf_2103 flagellar biosynthesis/type III secretory pathway protein K02411 fliH; flagellar assembly protein FliH D Spiaf_2102 ATPase FliI/YscN family K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8] D Spiaf_2091 flagellar motor switch protein FliN K02417 fliN; flagellar motor switch protein FliN D Spiaf_2090 flagellar biogenesis protein K02418 fliO; flagellar protein FliO/FliZ D Spiaf_2089 flagellar biosynthetic protein FliP K02419 fliP; flagellar biosynthesis protein FliP D Spiaf_2088 flagellar biosynthetic protein FliQ K02420 fliQ; flagellar biosynthesis protein FliQ D Spiaf_2087 flagellar biosynthetic protein FliR K02421 fliR; flagellar biosynthesis protein FliR D Spiaf_0310 P pilus assembly protein, chaperone PapD K07346 fimC; fimbrial chaperone protein D Spiaf_0781 preprotein translocase, SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D Spiaf_0202 protein-export membrane protein, SecD/SecF family K03072 secD; preprotein translocase subunit SecD D Spiaf_0542 preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE D Spiaf_0203 protein-export membrane protein, SecD/SecF family K03074 secF; preprotein translocase subunit SecF D Spiaf_1630 protein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG D Spiaf_0574 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Spiaf_1211 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D Spiaf_1058 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Spiaf_0201 preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC D Spiaf_0007 membrane protein insertase, YidC/Oxa1 family, N-terminal domain protein K03217 yidC; YidC/Oxa1 family membrane protein insertase C 02042 Bacterial toxins [BR:sfc02042] D Spiaf_2639 CBS domain-containing protein K03699 tlyC; magnesium and cobalt exporter, CNNM family D Spiaf_1309 putative membrane protein, hemolysin III K11068 hlyIII; hemolysin III C 02022 Two-component system [BR:sfc02022] D Spiaf_0643 signal transduction histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D Spiaf_0644 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB D Spiaf_2056 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K07662 cpxR; two-component system, OmpR family, response regulator CpxR D Spiaf_2666 histidine kinase,HAMP domain-containing protein,histidine kinase K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3] D Spiaf_2665 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX D Spiaf_1869 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_2075 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_2374 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_1671 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_0148 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_1857 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_1866 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_0607 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_2376 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_2425 response regulator containing a CheY-like receiver domain and a GGDEF domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_1855 response regulator containing a CheY-like receiver domain and a GGDEF domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_2305 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_1668 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_1056 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_1160 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_1867 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Spiaf_2678 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Spiaf_0215 PAS domain S-box K13924 cheBR; two-component system, chemotaxis family, CheB/CheR fusion protein [EC:2.1.1.80 3.1.1.61] D Spiaf_0216 CheY-like receiver domain-containing protein K11443 divK; two-component system, cell cycle response regulator DivK D Spiaf_1865 histidine kinase,Response regulator receiver domain protein,PAS domain-containing protein,histidine kinase K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3] D Spiaf_0272 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K07720 yesN; two-component system, response regulator YesN D Spiaf_0354 signal transduction histidine kinase K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3] D Spiaf_1066 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K22010 pdtaR; two-component system, response regulator PdtaR D Spiaf_2065 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K22010 pdtaR; two-component system, response regulator PdtaR D Spiaf_2373 signal transduction histidine kinase K20971 ladS; two-component system, sensor histidine kinase LadS D Spiaf_1103 histidine kinase,Response regulator receiver domain protein,histidine kinase K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3] C 02035 Bacterial motility proteins [BR:sfc02035] D Spiaf_1869 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_2075 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_2374 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_1671 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_0148 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_1857 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spiaf_1670 chemotaxis signal transduction protein K03408 cheW; purine-binding chemotaxis protein CheW D Spiaf_2133 chemotaxis signal transduction protein K03408 cheW; purine-binding chemotaxis protein CheW D Spiaf_2812 chemotaxis signal transduction protein K03408 cheW; purine-binding chemotaxis protein CheW D Spiaf_0608 hypothetical protein K03409 cheX; chemotaxis protein CheX D Spiaf_0941 putative inhibitor of MCP methylation, CheC K03409 cheX; chemotaxis protein CheX D Spiaf_1856 putative inhibitor of MCP methylation, CheC K03409 cheX; chemotaxis protein CheX D Spiaf_1669 putative inhibitor of MCP methylation, CheC K03409 cheX; chemotaxis protein CheX D Spiaf_2022 chemotaxis protein K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44] D Spiaf_1868 methylase of chemotaxis methyl-accepting protein K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Spiaf_2677 methylase of chemotaxis methyl-accepting protein K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Spiaf_1867 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Spiaf_2678 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Spiaf_0215 PAS domain S-box K13924 cheBR; two-component system, chemotaxis family, CheB/CheR fusion protein [EC:2.1.1.80 3.1.1.61] D Spiaf_1866 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_0607 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_2376 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_2425 response regulator containing a CheY-like receiver domain and a GGDEF domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_1855 response regulator containing a CheY-like receiver domain and a GGDEF domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_2305 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_1668 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_1056 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_1160 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spiaf_0140 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_0146 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_0157 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_1044 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_1087 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_0277 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2042 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2060 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2168 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_0417 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2280 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2378 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2433 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2434 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_0727 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2485 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_0823 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2579 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2633 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D Spiaf_2103 flagellar biosynthesis/type III secretory pathway protein K02411 fliH; flagellar assembly protein FliH D Spiaf_2102 ATPase FliI/YscN family K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8] D Spiaf_2101 flagellar export protein FliJ K02413 fliJ; flagellar protein FliJ D Spiaf_2090 flagellar biogenesis protein K02418 fliO; flagellar protein FliO/FliZ D Spiaf_2089 flagellar biosynthetic protein FliP K02419 fliP; flagellar biosynthesis protein FliP D Spiaf_2088 flagellar biosynthetic protein FliQ K02420 fliQ; flagellar biosynthesis protein FliQ D Spiaf_2087 flagellar biosynthetic protein FliR K02421 fliR; flagellar biosynthesis protein FliR D Spiaf_2085 flagellar biosynthesis protein FlhA K02400 flhA; flagellar biosynthesis protein FlhA D Spiaf_2086 flagellar biosynthetic protein FlhB K02401 flhB; flagellar biosynthesis protein FlhB D Spiaf_0601 flagellar motor switch protein K02410 fliG; flagellar motor switch protein FliG D Spiaf_2104 flagellar motor switch protein FliG K02410 fliG; flagellar motor switch protein FliG D Spiaf_2092 flagellar motor switch protein FliM K02416 fliM; flagellar motor switch protein FliM D Spiaf_2091 flagellar motor switch protein FliN K02417 fliN; flagellar motor switch protein FliN D Spiaf_2105 flagellar basal-body M-ring protein/flagellar hook-basal body protein FliF K02409 fliF; flagellar M-ring protein FliF D Spiaf_2093 flagellar basal body-associated protein K02415 fliL; flagellar protein FliL D Spiaf_2106 flagellar hook-basal body complex protein FliE K02408 fliE; flagellar hook-basal body complex protein FliE D Spiaf_2108 flagellar basal-body rod protein FlgB K02387 flgB; flagellar basal-body rod protein FlgB D Spiaf_2107 flagellar basal-body rod protein FlgC K02388 flgC; flagellar basal-body rod protein FlgC D Spiaf_2098 flagellar hook capping protein K02389 flgD; flagellar basal-body rod modification protein FlgD D Spiaf_1905 flagellar hook-basal body protein K02391 flgF; flagellar basal-body rod protein FlgF D Spiaf_1904 flagellar basal-body rod protein FlgG K02392 flgG; flagellar basal-body rod protein FlgG D Spiaf_1903 Rod binding protein K02395 flgJ; peptidoglycan hydrolase FlgJ D Spiaf_2097 flagellar hook-basal body protein K02390 flgE; flagellar hook protein FlgE D Spiaf_0794 flagellar hook-associated protein FlgK K02396 flgK; flagellar hook-associated protein 1 D Spiaf_0795 flagellar hook-associated protein 3 K02397 flgL; flagellar hook-associated protein 3 FlgL D Spiaf_1487 flagellin/flagellar hook associated protein K02406 fliC; flagellin D Spiaf_0805 flagellin/flagellar hook associated protein K02406 fliC; flagellin D Spiaf_0806 flagellin/flagellar hook associated protein K02406 fliC; flagellin D Spiaf_0803 flagellar capping protein K02407 fliD; flagellar hook-associated protein 2 D Spiaf_2718 flagellar biosynthetic protein FliS K02422 fliS; flagellar secretion chaperone FliS D Spiaf_2081 RNA polymerase sigma factor, FliA/WhiG family K02405 fliA; RNA polymerase sigma factor FliA D Spiaf_2095 flagellar motor component K02556 motA; chemotaxis protein MotA D Spiaf_2094 flagellar motor protein K02557 motB; chemotaxis protein MotB D Spiaf_0796 hypothetical protein K13626 fliW; flagellar assembly factor FliW D Spiaf_0804 flagellar protein FlaG K06603 flaG; flagellar protein FlaG D Spiaf_2100 hypothetical protein K02383 flbB; flagellar protein FlbB D Spiaf_2096 uncharacterized protein, possibly involved in motility K02385 flbD; flagellar protein FlbD D Spiaf_2084 flagellar biosynthetic protein FlhF K02404 flhF; flagellar biosynthesis protein FlhF D Spiaf_1899 ATPase involved in chromosome partitioning K04562 flhG; flagellar biosynthesis protein FlhG D Spiaf_2779 ATPase involved in chromosome partitioning K04562 flhG; flagellar biosynthesis protein FlhG D Spiaf_2083 ATPase involved in chromosome partitioning K04562 flhG; flagellar biosynthesis protein FlhG D Spiaf_0162 CobQ/CobB/MinD/ParA nucleotide binding domain-containing protein K04562 flhG; flagellar biosynthesis protein FlhG D Spiaf_1841 type IV leader peptidase K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D Spiaf_0310 P pilus assembly protein, chaperone PapD K07346 fimC; fimbrial chaperone protein C 03037 Cilium and associated proteins [BR:sfc03037] D Spiaf_0925 NhaP-type Na+(K+)/H+ antiporter K23994 SLC9B1_2; solute carrier family 9B (sodium/hydrogen exchanger), member 1/2 C 04812 Cytoskeleton proteins [BR:sfc04812] D Spiaf_0320 putative dioxygenase K06990 MEMO1; MEMO1 family protein D Spiaf_1504 cell shape determining protein, MreB/Mrl family K03569 mreB; rod shape-determining protein MreB and related proteins D Spiaf_2116 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D Spiaf_2117 cell division protein FtsA K03590 ftsA; cell division protein FtsA D Spiaf_2870 ATPase involved in chromosome partitioning K03496 parA; chromosome partitioning protein D Spiaf_1360 ATPase involved in chromosome partitioning K03496 parA; chromosome partitioning protein D Spiaf_2869 putative transcriptional regulator K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Spiaf_1915 putative transcriptional regulator K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein C 04147 Exosome [BR:sfc04147] D Spiaf_2634 molecular chaperone of HSP90 family K04079 HSP90A; molecular chaperone HtpG D Spiaf_0670 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Spiaf_1633 glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D Spiaf_1632 3-phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D Spiaf_2001 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Spiaf_2707 peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D Spiaf_0199 chaperonin GroL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Spiaf_2077 molecular chaperone K04043 dnaK; molecular chaperone DnaK D Spiaf_1960 chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK D Spiaf_0190 glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Spiaf_1610 inosine-5''-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D Spiaf_0552 translation elongation factor TU K02358 tuf; elongation factor Tu D Spiaf_2700 HIT family hydrolase, diadenosine tetraphosphate hydrolase K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D Spiaf_2292 L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D Spiaf_0085 AMP-forming long-chain acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1710 AMP-forming long-chain acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1768 AMP-forming long-chain acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_0924 AMP-forming long-chain acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1302 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_1303 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spiaf_2588 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Spiaf_0010 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D Spiaf_2149 adenylate kinase family protein K00939 adk; adenylate kinase [EC:2.7.4.3] D Spiaf_1898 PRPP-binding protein, adenine/guanine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D Spiaf_2010 argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D Spiaf_0191 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D Spiaf_2395 galactokinase K00849 galK; galactokinase [EC:2.7.1.6] D Spiaf_1934 galactokinase K00849 galK; galactokinase [EC:2.7.1.6] D Spiaf_0325 glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30] D Spiaf_0307 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Spiaf_1199 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Spiaf_0366 formyltetrahydrofolate synthetase K00288 MTHFD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3] D Spiaf_2706 phosphoglycerate dehydrogenase-like oxidoreductase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Spiaf_1616 AICAR transformylase/IMP cyclohydrolase PurH K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D Spiaf_1800 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_0773 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spiaf_0198 glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D Spiaf_1631 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D Spiaf_1156 fructose-2,6-bisphosphatase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] C 02048 Prokaryotic defense system [BR:sfc02048] D Spiaf_0403 CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1 D Spiaf_0404 CRISPR-associated helicase Cas3, subtype I-F/YPEST K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] D Spiaf_0405 CRISPR type I-F/YPEST-associated protein Csy1 K19127 csy1; CRISPR-associated protein Csy1 D Spiaf_0406 CRISPR type I-F/YPEST-associated protein Csy2 K19128 csy2; CRISPR-associated protein Csy2 D Spiaf_0407 CRISPR type I-F/YPEST-associated protein Csy3 K19129 csy3; CRISPR-associated protein Csy3 D Spiaf_0408 CRISPR-associated protein Cas6/Csy4, subtype I-F/YPEST K19130 csy4; CRISPR-associated endonuclease Csy4 [EC:3.1.-.-] D Spiaf_1714 adenine-specific DNA methylase K07318 K07318; adenine-specific DNA-methyltransferase [EC:2.1.1.72] D Spiaf_0875 DNA-methyltransferase Dcm K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Spiaf_0867 putative restriction endonuclease K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-] D Spiaf_0856 PemK-like protein K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] D Spiaf_0465 addiction module toxin, RelE/StbE family K06218 relE; mRNA interferase RelE/StbE D Spiaf_0017 hypothetical protein K06218 relE; mRNA interferase RelE/StbE D Spiaf_1251 putative stress-responsive transcriptional regulator K03973 pspC; phage shock protein C D Spiaf_0662 addiction module toxin, RelE/StbE family K19092 parE1_3_4; toxin ParE1/3/4 D Spiaf_1739 hypothetical protein K21498 higA-1; antitoxin HigA-1 D Spiaf_0435 putative nucleic acid-binding protein, contains PIN domain K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-] D Spiaf_0045 putative nucleic acid-binding protein, contains PIN domain K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-] D Spiaf_0439 hypothetical protein K21495 fitA; antitoxin FitA D Spiaf_2116 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D Spiaf_1504 cell shape determining protein, MreB/Mrl family K03569 mreB; rod shape-determining protein MreB and related proteins D Spiaf_2055 type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D Spiaf_2054 type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D Spiaf_1924 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] C 04030 G protein-coupled receptors C 04050 Cytokine receptors C 04054 Pattern recognition receptors C 03310 Nuclear receptors C 04040 Ion channels C 04031 GTP-binding proteins C 04052 Cytokines and neuropeptides C 04515 Cell adhesion molecules C 04090 CD molecules [BR:sfc04090] C 01504 Antimicrobial resistance genes [BR:sfc01504] D Spiaf_0389 putative aminoglycoside phosphotransferase K06979 mph; macrolide phosphotransferase D Spiaf_1438 D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D Spiaf_2585 RND family efflux transporter, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Spiaf_2841 RND family efflux transporter, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Spiaf_2840 outer membrane protein K18139 oprM; outer membrane protein, multidrug efflux system D Spiaf_2315 outer membrane protein K12340 tolC; outer membrane protein D Spiaf_0099 outer membrane protein K12340 tolC; outer membrane protein C 00535 Proteoglycans C 00536 Glycosaminoglycan binding proteins C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins C 04091 Lectins C 04990 Domain-containing proteins not elsewhere classified B B 09185 Viral protein families C 03200 Viral proteins C 03210 Viral fusion proteins B B 09184 RNA family C 03100 Non-coding RNAs [BR:sfc03100] D Spiaf_2595 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Spiaf_0234 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Spiaf_2380 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Spiaf_1344 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Spiaf_1145 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Spiaf_1984 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Spiaf_0315 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Spiaf_2866 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Spiaf_1467 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D Spiaf_1861 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D Spiaf_0330 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D Spiaf_1877 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Spiaf_1897 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Spiaf_2154 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Spiaf_1203 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Spiaf_0838 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Spiaf_1142 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Spiaf_1146 tRNA-His K14226 tRNA-His; tRNA His D Spiaf_2141 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Spiaf_2146 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Spiaf_2686 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Spiaf_1131 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Spiaf_1143 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Spiaf_0341 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Spiaf_0822 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Spiaf_2155 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Spiaf_1144 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Spiaf_0971 tRNA-Met K14230 tRNA-Met; tRNA Met D Spiaf_2015 tRNA-Met K14230 tRNA-Met; tRNA Met D Spiaf_2503 tRNA-Met K14230 tRNA-Met; tRNA Met D Spiaf_0600 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D Spiaf_1345 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Spiaf_0729 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Spiaf_1860 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Spiaf_2867 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Spiaf_2868 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Spiaf_2865 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Spiaf_2864 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Spiaf_0540 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Spiaf_1494 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Spiaf_1909 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Spiaf_0541 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D Spiaf_1495 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D Spiaf_1476 tRNA-Val K14237 tRNA-Val; tRNA Val D Spiaf_1667 tRNA-Val K14237 tRNA-Val; tRNA Val D Spiaf_2142 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Spiaf_2147 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Spiaf_2596 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Spiaf_2594 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Spiaf_2140 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Spiaf_2145 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Spiaf_2593 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Spiaf_2144 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Spiaf_2139 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Spiaf_2863 Bacterial signal recognition particle RNA K01983 ffs; SRP RNA # A09190 Not Included in Pathway or Brite B B 09191 Unclassified: metabolism C 99980 Enzymes with EC numbers D Spiaf_2390 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein K16216 yueD; benzil reductase ((S)-benzoin forming) [EC:1.1.1.320] D Spiaf_2431 glucose/sorbosone dehydrogenase K21430 yliI; aldose sugar dehydrogenase [EC:1.1.5.-] D Spiaf_2223 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS-like protein K03518 coxS; aerobic carbon-monoxide dehydrogenase small subunit [EC:1.2.5.3] D Spiaf_0650 saccharopine dehydrogenase-like oxidoreductase K27502 E1.5.1.55; carboxyaminopropylagmatine dehydrogenase [EC:1.5.1.55] D Spiaf_0905 putative NAD/FAD-dependent oxidoreductase K18208 RNLS; renalase [EC:1.6.3.5] D Spiaf_2693 alkyl hydroperoxide reductase, F subunit K03387 ahpF; NADH-dependent peroxiredoxin subunit F [EC:1.8.1.-] D Spiaf_2438 thioredoxin reductase K26960 bdr; bacillithiol disulfide reductase [EC:1.8.1.-] D Spiaf_1765 methionine-S-sulfoxide reductase K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11] D Spiaf_2689 methionine-R-sulfoxide reductase K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12] D Spiaf_0363 ferredoxin-thioredoxin reductase, catalytic subunit K17892 FTRC; ferredoxin-thioredoxin reductase catalytic chain [EC:1.8.7.2] D Spiaf_2616 Peroxiredoxin K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24] D Spiaf_1826 peroxiredoxin K11065 tpx; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24] D Spiaf_2694 peroxiredoxin K24119 ahpC; NADH-dependent peroxiredoxin subunit C [EC:1.11.1.26] D Spiaf_2407 ferredoxin K17992 hndB; NADP-reducing hydrogenase subunit HndB [EC:1.12.1.3] D Spiaf_1750 hydrogenase, Fe-only K18332 hndD; NADP-reducing hydrogenase subunit HndD [EC:1.12.1.3] D Spiaf_2409 hydrogenase, Fe-only K18332 hndD; NADP-reducing hydrogenase subunit HndD [EC:1.12.1.3] D Spiaf_1745 flavodoxin reductase family protein K00528 fpr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1] D Spiaf_2824 2-polyprenylphenol hydroxylase-like oxidoreductase K00528 fpr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1] D Spiaf_1769 protein-tyrosine-phosphatase K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4] D Spiaf_2420 pyruvate formate-lyase 1-activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D Spiaf_2302 anaerobic ribonucleoside-triphosphate reductase activating protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D Spiaf_0319 pyruvate-formate lyase-activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D Spiaf_0898 pyruvate formate lyase activating protein-like uncharacterized Fe-S protein K04070 pflX; putative pyruvate formate lyase activating enzyme [EC:1.97.1.4] D Spiaf_1829 protein-L-isoaspartate and D-aspartate O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77] D Spiaf_2586 putative N6-adenine-specific DNA methylase K07444 ypsC; putative N6-adenine-specific DNA methylase [EC:2.1.1.-] D Spiaf_2354 putative carbamoyl transferase, NodU family K00612 nodU; carbamoyltransferase [EC:2.1.3.-] D Spiaf_1002 acetyltransferase K22441 paiA; diamine N-acetyltransferase [EC:2.3.1.57] D Spiaf_2261 acetyltransferase (isoleucine patch superfamily) K00661 maa; maltose O-acetyltransferase [EC:2.3.1.79] D Spiaf_2782 apolipoprotein N-acyltransferase K03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269] D Spiaf_1935 apolipoprotein N-acyltransferase K03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269] D Spiaf_1942 apolipoprotein N-acyltransferase K03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269] D Spiaf_1928 leucyl/phenylalanyl-tRNA--protein transferase K00684 aat; leucyl/phenylalanyl-tRNA---protein transferase [EC:2.3.2.6] D Spiaf_1195 trehalose/maltose hydrolase or phosphorylase K21355 ggp; 1,2-alpha-glucosylglycerol phosphorylase [EC:2.4.1.332] D Spiaf_2781 prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145] D Spiaf_2807 membrane-associated lipoprotein involved in thiamine biosynthesis K03734 apbE; FAD:protein FMN transferase [EC:2.7.1.180] D Spiaf_2799 dolichol kinase K18678 VTE5; phytol kinase [EC:2.7.1.182] D Spiaf_0306 glutamine synthetase adenylyltransferase K00982 glnE; [glutamine synthetase] adenylyltransferase / [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase [EC:2.7.7.42 2.7.7.89] D Spiaf_1006 Retron-type reverse transcriptase K00986 ltrA; RNA-directed DNA polymerase [EC:2.7.7.49] D Spiaf_1073 TIGR00159 family protein K18672 dacA; diadenylate cyclase [EC:2.7.7.85] D Spiaf_1081 phosphotransferase system mannitol/fructose-specifc IIA component (Ntr-type) K18672 dacA; diadenylate cyclase [EC:2.7.7.85] D Spiaf_2669 Hpr(Ser) kinase/phosphatase K06023 hprK; HPr kinase/phosphorylase [EC:2.7.11.- 2.7.4.-] D Spiaf_1063 arginine kinase K19405 mcsB; protein arginine kinase [EC:2.7.14.1] D Spiaf_1485 esterase/lipase K03928 yvaK; carboxylesterase [EC:3.1.1.1] D Spiaf_0930 putative phosphatase, C-terminal domain of histone macro H2A1 like protein K23518 MACROD; O-acetyl-ADP-ribose deacetylase [EC:3.1.1.106] D Spiaf_2569 putative thioesterase K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-] D Spiaf_0821 Mg-dependent DNase K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D Spiaf_2631 Mg-dependent DNase K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D Spiaf_1952 hydrolase, TatD family K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D Spiaf_0135 family 31 glycosyl hydrolase, alpha-glucosidase K15922 yihQ; sulfoquinovosidase [EC:3.2.1.199] D Spiaf_1090 peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88] D Spiaf_1034 endoribonuclease L-PSP, putative K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10] D Spiaf_2537 MoxR-like ATPase K03924 moxR; MoxR-like ATPase [EC:3.6.3.-] D Spiaf_0285 MoxR-like ATPase K03924 moxR; MoxR-like ATPase [EC:3.6.3.-] D Spiaf_0783 yjeF-like protein K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6] D Spiaf_0531 electron transport complex, RnfABCDGE type, D subunit K03614 rnfD; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit D [EC:7.1.1.11 7.2.1.2] D Spiaf_0530 electron transport complex, RnfABCDGE type, C subunit K03615 rnfC; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit C [EC:7.1.1.11 7.2.1.2] D Spiaf_0529 putative NADH:ubiquinone oxidoreductase, subunit RnfB K03616 rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2] D Spiaf_1805 putative NADH:ubiquinone oxidoreductase, subunit RnfD K00347 nqrB; Na+-transporting NADH:ubiquinone oxidoreductase subunit B [EC:7.2.1.1] D Spiaf_1806 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC K00348 nqrC; Na+-transporting NADH:ubiquinone oxidoreductase subunit C [EC:7.2.1.1] D Spiaf_1807 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD K00349 nqrD; Na+-transporting NADH:ubiquinone oxidoreductase subunit D [EC:7.2.1.1] D Spiaf_1808 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE K00350 nqrE; Na+-transporting NADH:ubiquinone oxidoreductase subunit E [EC:7.2.1.1] D Spiaf_1809 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF K00351 nqrF; Na+-transporting NADH:ubiquinone oxidoreductase subunit F [EC:7.2.1.1] D Spiaf_0719 heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21] D Spiaf_2236 heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21] C 99981 Carbohydrate metabolism D Spiaf_1306 putative signal-transduction protein containing cAMP-binding and CBS domains K04767 acuB; acetoin utilization protein AcuB C 99982 Energy metabolism D Spiaf_0532 electron transport complex, RnfABCDGE type, G subunit K03612 rnfG; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit G D Spiaf_0533 electron transport complex, RnfABCDGE type, E subunit K03613 rnfE; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit E D Spiaf_0534 electron transport complex, RnfABCDGE type, A subunit K03617 rnfA; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit A D Spiaf_1038 iron-sulfur cluster biosynthesis protein, NifU-like protein K04488 iscU; nitrogen fixation protein NifU and related proteins D Spiaf_0537 flavodoxin, long chain K03839 fldA; flavodoxin I C 99983 Lipid metabolism C 99984 Nucleotide metabolism C 99985 Amino acid metabolism D Spiaf_0756 pyridoxal phosphate enzyme, YggS family K06997 yggS; PLP dependent protein C 99986 Glycan metabolism C 99987 Cofactor metabolism D Spiaf_1067 putative unusual protein kinase K03688 ubiB; ubiquinone biosynthesis protein C 99988 Secondary metabolism C 99999 Others D Spiaf_1853 lactoylglutathione lyase-like lyase K15975 K15975; glyoxalase family protein D Spiaf_0102 putative esterase K06999 K06999; phospholipase/carboxylesterase D Spiaf_1707 putative esterase K06999 K06999; phospholipase/carboxylesterase B B 09192 Unclassified: genetic information processing C 99973 Transcription D Spiaf_1597 prophage antirepressor K07741 antB; anti-repressor protein D Spiaf_2004 nitrogen regulatory protein PII K04752 glnK; nitrogen regulatory protein P-II 2 D Spiaf_1756 transcriptional accessory protein K06959 tex; protein Tex C 99974 Translation C 99975 Protein processing D Spiaf_1930 hypothetical protein K06891 clpS; ATP-dependent Clp protease adaptor protein ClpS D Spiaf_1141 trigger factor K03545 tig; trigger factor D Spiaf_1558 SsrA-binding protein K03664 smpB; SsrA-binding protein D Spiaf_0364 glutaredoxin-like protein K06191 nrdH; glutaredoxin-like protein NrdH D Spiaf_0582 Mg chelatase-related protein K07391 comM; magnesium chelatase family protein D Spiaf_0225 putative redox protein, regulator of disulfide bond formation K07397 yhfA; putative redox protein D Spiaf_2037 putative redox protein, regulator of disulfide bond formation K07397 yhfA; putative redox protein D Spiaf_0902 selT/selW/selH selenoprotein domain protein K07401 K07401; selenoprotein W-related protein C 99976 Replication and repair D Spiaf_2066 DNA repair protein radc K03630 radC; DNA repair protein RadC D Spiaf_0463 hypothetical protein K09760 rmuC; DNA recombination protein RmuC D Spiaf_0349 putative endonuclease III-like protein K07457 K07457; endonuclease III related protein D Spiaf_1220 putative endonuclease related to Holliday junction resolvase K07460 yraN; putative endonuclease D Spiaf_2112 DNA protecting protein DprA K04096 smf; DNA processing protein D Spiaf_1147 AAA ATPase K07478 ycaJ; putative ATPase D Spiaf_1119 transposase K07493 K07493; putative transposase D Spiaf_1123 transposase K07493 K07493; putative transposase D Spiaf_1128 transposase K07493 K07493; putative transposase D Spiaf_1246 transposase K07493 K07493; putative transposase D Spiaf_1310 transposase K07493 K07493; putative transposase D Spiaf_1342 transposase K07493 K07493; putative transposase D Spiaf_1378 transposase K07493 K07493; putative transposase D Spiaf_1380 transposase K07493 K07493; putative transposase D Spiaf_1404 transposase K07493 K07493; putative transposase D Spiaf_1406 transposase K07493 K07493; putative transposase D Spiaf_2271 transposase K07493 K07493; putative transposase D Spiaf_1509 transposase K07493 K07493; putative transposase D Spiaf_0761 transposase K07493 K07493; putative transposase D Spiaf_0770 transposase K07493 K07493; putative transposase D Spiaf_0870 transposase K07493 K07493; putative transposase D Spiaf_0880 transposase K07493 K07493; putative transposase D Spiaf_0015 transposase K07493 K07493; putative transposase D Spiaf_1008 transposase K07493 K07493; putative transposase D Spiaf_1015 transposase K07493 K07493; putative transposase D Spiaf_1019 transposase K07493 K07493; putative transposase C 99979 Viral proteins C 99998 Others D Spiaf_2770 phage shock protein A (IM30), suppresses sigma54-dependent transcription K03969 pspA; phage shock protein A D Spiaf_2861 DNA-binding protein, YbaB/EbfC family K09747 ebfC; nucleoid-associated protein EbfC B B 09193 Unclassified: signaling and cellular processes C 99977 Transport D Spiaf_0929 Na+/melibiose symporter-like transporter K03292 TC.GPH; glycoside/pentoside/hexuronide:cation symporter, GPH family D Spiaf_1297 glycoside/pentoside/hexuronide transporter K03292 TC.GPH; glycoside/pentoside/hexuronide:cation symporter, GPH family D Spiaf_0452 Na+/melibiose symporter-like transporter K03292 TC.GPH; glycoside/pentoside/hexuronide:cation symporter, GPH family D Spiaf_2298 amino acid transporter K03294 TC.APA; basic amino acid/polyamine antiporter, APA family D Spiaf_2842 cation/multidrug efflux pump K03296 TC.HAE1; hydrophobic/amphiphilic exporter-1 (mainly G- bacteria), HAE1 family D Spiaf_0447 phosphate/sulfate permease K03306 TC.PIT; inorganic phosphate transporter, PiT family D Spiaf_0954 Na+/proline symporter K03307 TC.SSS; solute:Na+ symporter, SSS family D Spiaf_0338 Na+/proline symporter K03307 TC.SSS; solute:Na+ symporter, SSS family D Spiaf_1304 Na+/proline symporter K03307 TC.SSS; solute:Na+ symporter, SSS family D Spiaf_0936 SNF family Na+-dependent transporter K03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family D Spiaf_2238 SNF family Na+-dependent transporter K03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family C 99978 Cell growth D Spiaf_0008 putative RNA-binding protein K06346 jag; spoIIIJ-associated protein D Spiaf_1357 site-specific recombinase, DNA invertase Pin K06400 spoIVCA; site-specific DNA recombinase D Spiaf_1878 uncharacterized protein, involved in the regulation of septum location K06412 spoVG; stage V sporulation protein G D Spiaf_1677 spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase K07257 spsF; spore coat polysaccharide biosynthesis protein SpsF D Spiaf_1973 sporulation/spore germination protein K06298 gerM; germination protein M C 99993 Cell motility C 99995 Signaling proteins D Spiaf_0217 GTP-binding protein TypA/BipA K06207 typA; GTP-binding protein D Spiaf_1109 ACT domain-containing protein K07166 K07166; ACT domain-containing protein D Spiaf_1637 phosphate starvation-inducible protein PhoH, predicted ATPase K06217 phoH; phosphate starvation-inducible protein PhoH and related proteins D Spiaf_2722 PhoH family protein K07175 phoH2; PhoH-like ATPase C 99992 Structural proteins D Spiaf_1545 outer membrane protein K06142 hlpA; outer membrane protein D Spiaf_1859 metalloendopeptidase-like membrane protein K12943 ygeR; lipoprotein YgeR D Spiaf_0996 multidrug resistance efflux pump K01993 ABC-2.TX; HlyD family secretion protein D Spiaf_0096 RND family efflux transporter, MFP subunit K02005 ABC.CD.TX; HlyD family secretion protein D Spiaf_0657 Helix-turn-helix protein K15539 rodZ; cytoskeleton protein RodZ C 99994 Others D Spiaf_0645 phosphate transport system regulatory protein PhoU K02039 phoU; phosphate transport system protein D Spiaf_2811 uncharacterized protein involved in tolerance to divalent cations K03926 cutA; periplasmic divalent cation tolerance protein D Spiaf_1182 hemerythrin-like metal-binding domain-containing protein K07216 hr; hemerythrin B B 09194 Poorly characterized C 99996 General function prediction only D Spiaf_0589 putative membrane protein, required for colicin V production K03558 cvpA; membrane protein required for colicin V production D Spiaf_2685 putative periplasmic lipoprotein K05811 yfiM; putative lipoprotein D Spiaf_0788 helicase family protein with metal-binding cysteine cluster K06877 K06877; DEAD/DEAH box helicase domain-containing protein D Spiaf_0429 export-related chaperone CsaA K06878 K06878; tRNA-binding protein D Spiaf_2346 putative esterase of the alpha-beta hydrolase superfamily K07001 K07001; NTE family protein D Spiaf_2138 putative esterase of the alpha-beta hydrolase superfamily K07001 K07001; NTE family protein D Spiaf_0250 putative esterase of the alpha-beta hydrolase superfamily K07001 K07001; NTE family protein D Spiaf_1963 haloacid dehalogenase superfamily enzyme, subfamily IA K07025 K07025; putative hydrolase of the HAD superfamily D Spiaf_0213 putative HAD superfamily hydrolase K07025 K07025; putative hydrolase of the HAD superfamily D Spiaf_1700 FeS assembly protein SufB K09014 sufB; Fe-S cluster assembly protein SufB D Spiaf_1699 FeS assembly protein SufD K09015 sufD; Fe-S cluster assembly protein SufD D Spiaf_0623 putative membrane protein K07058 K07058; membrane protein D Spiaf_2775 protein affecting phage T7 exclusion by the F plasmid K07113 fxsA; UPF0716 protein FxsA D Spiaf_1280 SufE protein probably involved in Fe-S center assembly K02426 sufE; cysteine desulfuration protein SufE D Spiaf_2308 putative sulfurtransferase K07146 K07146; UPF0176 protein D Spiaf_0959 hypothetical protein K03745 slyX; SlyX protein D Spiaf_0835 uncharacterized membrane protein K03748 sanA; SanA protein D Spiaf_2429 putative membrane protein K08974 K08974; putative membrane protein D Spiaf_2011 putative membrane protein K08974 K08974; putative membrane protein D Spiaf_0151 putative membrane protein K08981 K08981; putative membrane protein C 99997 Function unknown D Spiaf_1691 ankyrin repeat-containing protein K06867 K06867; uncharacterized protein D Spiaf_2608 ankyrin repeat-containing protein K06867 K06867; uncharacterized protein D Spiaf_2017 HD superfamily phosphohydrolase K06885 K06885; uncharacterized protein D Spiaf_0923 highly conserved protein containing a thioredoxin domain K06888 K06888; uncharacterized protein D Spiaf_1387 Putative lysophospholipase K06889 K06889; uncharacterized protein D Spiaf_2267 Dienelactone hydrolase family protein K06889 K06889; uncharacterized protein D Spiaf_2760 FtsH-interacting integral membrane protein K06890 K06890; uncharacterized protein D Spiaf_1496 putative Fe-S oxidoreductase K06940 K06940; uncharacterized protein D Spiaf_1213 putative RNA-binding protein (contains KH domain) K06960 K06960; uncharacterized protein D Spiaf_0791 putative acyltransferase K06976 K06976; uncharacterized protein D Spiaf_0956 putative RND superfamily exporter K07003 K07003; uncharacterized protein D Spiaf_1004 putative nucleic acid-binding protein, contains PIN domain K07065 K07065; uncharacterized protein D Spiaf_0380 putative permease K07089 K07089; uncharacterized protein D Spiaf_2683 putative permease K07090 K07090; uncharacterized protein D Spiaf_0133 putative permease K07090 K07090; uncharacterized protein D Spiaf_1622 putative phosphoribosyltransferase K07101 K07101; uncharacterized protein D Spiaf_2691 YeeE/YedE family protein (DUF395) K07112 K07112; uncharacterized protein D Spiaf_2692 YeeE/YedE family protein (DUF395) K07112 K07112; uncharacterized protein D Spiaf_1299 putative transporter component K07112 K07112; uncharacterized protein D Spiaf_0256 YeeE/YedE family protein (DUF395) K07112 K07112; uncharacterized protein D Spiaf_0257 YeeE/YedE family protein (DUF395) K07112 K07112; uncharacterized protein D Spiaf_1748 short-chain dehydrogenase of unknown substrate specificity K07124 K07124; uncharacterized protein D Spiaf_0368 short-chain dehydrogenase of unknown substrate specificity K07124 K07124; uncharacterized protein D Spiaf_0040 putative ATPase (AAA+ superfamily) K07133 K07133; uncharacterized protein D Spiaf_0433 putative ATPase (AAA+ superfamily) K07133 K07133; uncharacterized protein D Spiaf_1043 putative ATPase (AAA+ superfamily) K07133 K07133; uncharacterized protein D Spiaf_1111 putative Fe-S oxidoreductase K07139 K07139; uncharacterized protein D Spiaf_2466 uncharacterized membrane protein, possible Na+ channel or pump K07150 K07150; uncharacterized protein D Spiaf_1502 Zn-ribbon protein, possibly nucleic acid-binding protein K07164 K07164; uncharacterized protein D Spiaf_0313 hypothetical protein K08998 K08998; uncharacterized protein D Spiaf_0090 hypothetical protein K08999 K08999; uncharacterized protein D Spiaf_1682 hypothetical protein K09005 K09005; uncharacterized protein D Spiaf_0321 uncharacterized protein, PH0010 family K09141 K09141; uncharacterized protein D Spiaf_1108 hypothetical protein K09157 K09157; uncharacterized protein D Spiaf_0150 hypothetical protein K09167 K09167; uncharacterized protein D Spiaf_0866 hypothetical protein K09384 K09384; uncharacterized protein D Spiaf_2266 hypothetical protein K09702 K09702; uncharacterized protein D Spiaf_0196 putative polymerase with PALM domain, HD hydrolase domain and Zn ribbon K09749 K09749; uncharacterized protein D Spiaf_0527 putative polymerase with PALM domain, HD hydrolase domain and Zn ribbon K09749 K09749; uncharacterized protein D Spiaf_2306 putative polymerase with PALM domain, HD hydrolase domain and Zn ribbon K09749 K09749; uncharacterized protein D Spiaf_2080 putative polymerase with PALM domain, HD hydrolase domain and Zn ribbon K09749 K09749; uncharacterized protein D Spiaf_2780 putative polymerase with PALM domain, HD hydrolase domain and Zn ribbon K09749 K09749; uncharacterized protein D Spiaf_1456 hypothetical protein K09764 K09764; uncharacterized protein D Spiaf_1076 hypothetical protein K09766 K09766; uncharacterized protein D Spiaf_1180 hypothetical protein K09768 K09768; uncharacterized protein D Spiaf_1949 hypothetical protein K09770 K09770; uncharacterized protein D Spiaf_1051 hypothetical protein K09775 K09775; uncharacterized protein D Spiaf_2297 hypothetical protein K09790 K09790; uncharacterized protein D Spiaf_0896 hypothetical protein K09792 K09792; uncharacterized protein D Spiaf_2372 hypothetical protein K09793 K09793; uncharacterized protein D Spiaf_1901 hypothetical protein K09798 K09798; uncharacterized protein D Spiaf_0480 hypothetical protein K09807 K09807; uncharacterized protein D Spiaf_1764 hypothetical protein K09919 K09919; uncharacterized protein D Spiaf_2126 hypothetical protein K09942 K09942; uncharacterized protein D Spiaf_2166 hypothetical protein K09954 K09954; uncharacterized protein D Spiaf_1183 hypothetical protein K09973 K09973; uncharacterized protein D Spiaf_2748 hypothetical protein K01163 K01163; uncharacterized protein D Spiaf_0789 hypothetical protein K07502 yprB; uncharacterized protein ! #
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: April 27, 2024