+E Replication protein KO
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DNA Replication Proteins - Chania multitudinisentens
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
C CDK (cyclin dependent kinase)
C DDK (Dbf-4 dependent kinase)
C GINS complex
C Other initiation factors
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
C DNA polymerase epsilon complex
C DNA polymerase delta complex
C DNA polymerase gamma complex (mitochondrial)
C RPA (replication protein A)
C RFC (replication factor C)
C RNase H
D Z042_18270 ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
C Other elongation factors
B DNA Replication Termination Factors
C DNA methylation enzymes
D Z042_14775 modification methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D Z042_23095 DNA methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
C Prevention of re-replication factors
C Telomere proteins
D Shelterin complex
D TERB1-TERB2-MAJIN complex
D CST complex (animals)
D CST complex (yeast)
D RIF proteins
D SIR proteins
C Telomerase complex (animals)
D Dyskerin complex
C Telomerase complex (fungi)
D Sm core complex
C ELG1-RFC complex
C MRN complex
C Other termination factors
B DNA Topoisomerases
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AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
D Z042_13580 DNA-binding protein K05787 hupA; DNA-binding protein HU-alpha
D Z042_18910 transcriptional regulator HU subunit alpha K03530 hupB; DNA-binding protein HU-beta
D Z042_24050 ihfA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
D Z042_21855 ihfB; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
D Z042_12080 dnaA; chromosomal replication initiation protein K02313 dnaA; chromosomal replication initiator protein
D Z042_14070 DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D Z042_09545 DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D Z042_07725 DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D Z042_08345 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D Z042_07555 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D Z042_09510 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
E Z042_05885 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E Z042_12085 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E Z042_16250 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E Z042_19595 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E Z042_23485 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E Z042_18275 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Z042_19055 DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E Z042_16890 DNA polymerase III subunit psi K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]
E Z042_22865 DNA polymerase III subunit theta K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
E Z042_02930 DNA polymerase II K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
D RNase H
E Z042_18270 ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E Z042_05890 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D Other elongation factors
E Z042_11705 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E Z042_04270 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
E Z042_18270 ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E Z042_05890 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D RFC (replication factor C)
D Other elongation factors
B DNA Replication Termination Factors
C Terminus site-binding protein
D Z042_24650 DNA replication terminus site-binding protein K10748 tus; DNA replication terminus site-binding protein
C DNA methylation enzymes
D Z042_10170 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D Z042_01485 hypothetical protein K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D Z042_22915 DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
C Prevention of re-replication factors
D Z042_19800 replication initiation regulator SeqA K03645 seqA; negative modulator of initiation of replication
D Z042_04655 DNA replication initiation factor K10763 hda; DnaA-homolog protein
B DNA Topoisomerases
C Z042_03170 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
C Z042_12095 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
C Z042_08155 DNA topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
C Z042_08175 DNA topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
C Z042_00235 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C Z042_14105 DNA topoisomerase III K03169 topB; DNA topoisomerase III [EC:5.6.2.1]
C Z042_07565 DNA topoisomerase III K03169 topB; DNA topoisomerase III [EC:5.6.2.1]
C Z042_00490 DNA topoisomerase III K03169 topB; DNA topoisomerase III [EC:5.6.2.1]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 2, 2022