+D GENES KO #

  KEGG Orthology (KO) - Staphylococcus haemolyticus Sh29/312/L2

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A09100 Metabolism B B 09101 Carbohydrate metabolism C 00010 Glycolysis / Gluconeogenesis [PATH:shh00010] D ShL2_01252 glcK; glucokinase, ROK family K25026 glk; glucokinase [EC:2.7.1.2] D ShL2_01850 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D ShL2_01111 pfkA; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D ShL2_00454 fbp; fructose-1,6-bisphosphatase K04041 fbp3; fructose-1,6-bisphosphatase III [EC:3.1.3.11] D ShL2_00355 fdaB; fructose-bisphosphate aldolase K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D ShL2_00801 fbaA; tagatose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D ShL2_01964 tpi; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D ShL2_01966 gap; glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D ShL2_01123 gapB; glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59] D ShL2_01965 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D ShL2_00535 gpm; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D ShL2_02370 phosphoglycerate mutase family protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D ShL2_01963 pgm; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D ShL2_01962 eno; enolase (2-phosphoglycerate dehydrogenase) K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D ShL2_01112 pykA; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D ShL2_00346 ptsA_1; phosphoenolpyruvate-protein phosphotransferase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] D ShL2_01730 pdhA; pyruvate dehydrogenase E1 component subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D ShL2_01729 pdhB; pyruvate dehydrogenase E1 component subunit beta K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D ShL2_00149 bfmB_1; lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D ShL2_01728 pdhC; pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D ShL2_01727 pdhD_4; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00146 pdhD_2; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00150 pdhD_3; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_01281 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_01554 porA; pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D ShL2_01553 porB; 2-oxoglutarate ferredoxin oxidoreductase subunitbeta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D ShL2_00421 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D ShL2_00804 aldA; aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D ShL2_02157 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D ShL2_01077 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D ShL2_00342 acsA2; AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D ShL2_00618 galM; aldose 1-epimerase K01785 galM; aldose 1-epimerase [EC:5.1.3.3] D ShL2_00219 manB; phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D ShL2_01022 pckA; phosphoenolpyruvate carboxykinase K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] D ShL2_00350 bglA; glycoside hydrolase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D ShL2_01368 crr; phosphotransferase system glucose-specific IIA component K02777 crr; sugar PTS system EIIA component [EC:2.7.1.-] D ShL2_00272 PTS system maltose/glucose-specific IICB component K02791 malX; maltose/glucose PTS system EIICB component [EC:2.7.1.199 2.7.1.208] D ShL2_00417 PTS system, glucose-specific IICBA component K20118 ptsG; glucose PTS system EIICBA or EIICB component [EC:2.7.1.199] C 00020 Citrate cycle (TCA cycle) [PATH:shh00020] D ShL2_01115 citZ; methylcitrate synthase K01647 CS; citrate synthase [EC:2.3.3.1] D ShL2_01435 citB; aconitate hydratase K01681 ACO; aconitate hydratase [EC:4.2.1.3] D ShL2_01116 citC; isocitrate dehydrogenase K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42] D ShL2_01376 kgd; oxoglutarate dehydrogenase (succinyl-transferring) E1 K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] D ShL2_01377 odhB; dihydrolipoamide succinyltransferase E2 component of 2-oxoglutarate dehydrogenase complex K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61] D ShL2_01727 pdhD_4; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00146 pdhD_2; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00150 pdhD_3; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_01281 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_01554 porA; pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D ShL2_01553 porB; 2-oxoglutarate ferredoxin oxidoreductase subunitbeta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D ShL2_01600 sucD; succinate--CoA ligase (ADP-forming) alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D ShL2_01601 sucC; succinate--CoA ligase (ADP-forming) beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D ShL2_01683 sdhA; succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D ShL2_01682 sdhB; succinate dehydrogenase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D ShL2_01684 sdhC; succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 sdhC; succinate dehydrogenase cytochrome b subunit D ShL2_00995 fumC; fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2] D ShL2_00592 mqo1; malate:quinone oxidoreductase 1 K00116 mqo; malate dehydrogenase (quinone) [EC:1.1.5.4] D ShL2_00348 mqo2; malate:quinone oxidoreductase 2 K00116 mqo; malate dehydrogenase (quinone) [EC:1.1.5.4] D ShL2_01708 pycA_1; pyruvate carboxylase K01958 PC; pyruvate carboxylase [EC:6.4.1.1] D ShL2_01022 pckA; phosphoenolpyruvate carboxykinase K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] D ShL2_01730 pdhA; pyruvate dehydrogenase E1 component subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D ShL2_01729 pdhB; pyruvate dehydrogenase E1 component subunit beta K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D ShL2_00149 bfmB_1; lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D ShL2_01728 pdhC; pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] C 00030 Pentose phosphate pathway [PATH:shh00030] D ShL2_01850 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D ShL2_01293 zwf; glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D ShL2_00920 3-carboxy-cis,cis-muconate lactonizing enzyme K07404 pgl; 6-phosphogluconolactonase [EC:3.1.1.31] D ShL2_01289 gnd; 6-phosphogluconate dehydrogenase K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] D ShL2_01625 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D ShL2_01442 tktA; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D ShL2_01028 tal; translaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2] D ShL2_00620 rpiA; ribose 5-phosphate isomerase K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D ShL2_02215 hxlA; 3-hexulose-6-phosphate synthase K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43] D ShL2_02214 6-phospho-3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27] D ShL2_00788 deoC2; deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4] D ShL2_00101 rbsK; ribokinase K00852 rbsK; ribokinase [EC:2.7.1.15] D ShL2_00790 drm; phosphopentomutase K01839 deoB; phosphopentomutase [EC:5.4.2.7] D ShL2_00219 manB; phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D ShL2_02296 prs; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D ShL2_00694 fabG_1; 3-oxoacyl-ACP reductase K00034 gdh; glucose 1-dehydrogenase [EC:1.1.1.47] D ShL2_00469 gntK_2; gluconokinase K25031 gntK; gluconokinase [EC:2.7.1.12] D ShL2_00355 fdaB; fructose-bisphosphate aldolase K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D ShL2_00801 fbaA; tagatose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D ShL2_00454 fbp; fructose-1,6-bisphosphatase K04041 fbp3; fructose-1,6-bisphosphatase III [EC:3.1.3.11] D ShL2_01111 pfkA; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] C 00040 Pentose and glucuronate interconversions [PATH:shh00040] D ShL2_00473 galU; UTP--glucose-1-phosphate uridylyltransferase subunit GalU K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D ShL2_01625 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D ShL2_00432 gntK_1; gluconokinase K00854 xylB; xylulokinase [EC:2.7.1.17] D ShL2_00139 zinc-binding alcohol dehydrogenase K00008 SORD; L-iditol 2-dehydrogenase [EC:1.1.1.14] C 00051 Fructose and mannose metabolism [PATH:shh00051] D ShL2_00881 fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D ShL2_00782 manA1; mannose-6 phosphate isomerase pmi K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] D ShL2_01111 pfkA; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D ShL2_00454 fbp; fructose-1,6-bisphosphatase K04041 fbp3; fructose-1,6-bisphosphatase III [EC:3.1.3.11] D ShL2_02043 pfkB; fructose 1-phosphate kinase K00882 fruK; 1-phosphofructokinase [EC:2.7.1.56] D ShL2_00139 zinc-binding alcohol dehydrogenase K00008 SORD; L-iditol 2-dehydrogenase [EC:1.1.1.14] D ShL2_00355 fdaB; fructose-bisphosphate aldolase K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D ShL2_00801 fbaA; tagatose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D ShL2_01964 tpi; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D ShL2_02042 PTS system D-fructose-specific transporter subunit IIABC K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] D ShL2_00153 mtlA; PTS system mannitol-specific IIBC component K02800 mtlA; mannitol PTS system EIICBA or EIICB component [EC:2.7.1.197] C 00052 Galactose metabolism [PATH:shh00052] D ShL2_00618 galM; aldose 1-epimerase K01785 galM; aldose 1-epimerase [EC:5.1.3.3] D ShL2_00473 galU; UTP--glucose-1-phosphate uridylyltransferase subunit GalU K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D ShL2_00219 manB; phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D ShL2_01252 glcK; glucokinase, ROK family K25026 glk; glucokinase [EC:2.7.1.2] D ShL2_00739 lacC; tagatose-6-phosphate kinase K00917 lacC; tagatose 6-phosphate kinase [EC:2.7.1.144] D ShL2_01111 pfkA; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D ShL2_00740 lacD; tagatose 1,6-diphosphate aldolase K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40] D ShL2_00737 lacA; galactose-6-phosphate isomerase subunit LacA K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26] D ShL2_00738 lacB; galactose-6-phosphate isomerase LacB subunit K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26] D ShL2_00743 lacG; 6-phospho-beta-galactosidase K01220 E3.2.1.85; 6-phospho-beta-galactosidase [EC:3.2.1.85] D ShL2_00741 PTS system lactose/cellobiose-specific IIA component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207] D ShL2_00742 PTS system lactose/cellobiose-specific IIBC component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207] D ShL2_00880 scrB; sucrose-6-phosphate hydrolase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26] D ShL2_01291 malA; alpha amylase K01187 malZ; alpha-glucosidase [EC:3.2.1.20] C 00053 Ascorbate and aldarate metabolism D ShL2_00804 aldA; aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D ShL2_02157 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] C 00500 Starch and sucrose metabolism [PATH:shh00500] D ShL2_00571 PTS system sucrose-specific IIBC component K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211] D ShL2_00641 murP; N-acetylmuramic acid phosphotransfer permease K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211] D ShL2_00880 scrB; sucrose-6-phosphate hydrolase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26] D ShL2_01291 malA; alpha amylase K01187 malZ; alpha-glucosidase [EC:3.2.1.20] D ShL2_00473 galU; UTP--glucose-1-phosphate uridylyltransferase subunit GalU K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D ShL2_00115 PTS system lactose/cellobiose-specific IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D ShL2_00113 licB; Lichenan-specific phosphotransferase enzyme IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D ShL2_00114 PTS system lactose/cellobiose-specific IIBC component K02761 celB; cellobiose PTS system EIIC component D ShL2_00350 bglA; glycoside hydrolase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D ShL2_01368 crr; phosphotransferase system glucose-specific IIA component K02777 crr; sugar PTS system EIIA component [EC:2.7.1.-] D ShL2_00272 PTS system maltose/glucose-specific IICB component K02791 malX; maltose/glucose PTS system EIICB component [EC:2.7.1.199 2.7.1.208] D ShL2_00632 PTS system glucose-specific IIBC component K02750 glvC; alpha-glucoside PTS system EIICB component [EC:2.7.1.208 2.7.1.-] D ShL2_02323 PTS system trehalose-specific IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D ShL2_02322 treC; alpha, alpha-phosphotrehalase K01226 treC; trehalose-6-phosphate hydrolase [EC:3.2.1.93] D ShL2_00219 manB; phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D ShL2_01252 glcK; glucokinase, ROK family K25026 glk; glucokinase [EC:2.7.1.2] D ShL2_01850 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D ShL2_00881 fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] C 00520 Amino sugar and nucleotide sugar metabolism [PATH:shh00520] D ShL2_01368 crr; phosphotransferase system glucose-specific IIA component K02777 crr; sugar PTS system EIIA component [EC:2.7.1.-] D ShL2_01085 ptaA; phosphotransferase system, N-acetylglucosamine-specific IIBC component K02804 nagE; N-acetylglucosamine PTS system EIICBA or EIICB component [EC:2.7.1.193] D ShL2_00194 nagA; N-acetylglucosamine-6-phosphate deacetylase K01443 nagA; N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25] D ShL2_00196 nagB; glucosamine/galactosamine-6-phosphate isomerase K02564 nagB; glucosamine-6-phosphate deaminase [EC:3.5.99.6] D ShL2_00881 fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D ShL2_00773 glmS; glucosamine--fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D ShL2_00772 glmM; phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10] D ShL2_02297 gcaD; UDP-N-acetylglucosamine pyrophosphorylase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157] D ShL2_00642 murQ; N-acetylmuramic acid 6-phosphate etherase K07106 murQ; N-acetylmuramic acid 6-phosphate etherase [EC:4.2.1.126] D ShL2_00802 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D ShL2_00826 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D ShL2_02006 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D ShL2_00197 nanE; N-acetylmannosamine-6-phosphate 2-epimerase K01788 nanE; N-acylglucosamine-6-phosphate 2-epimerase [EC:5.1.3.9] D ShL2_00200 nanA; N-acetylneuraminate lyase K01639 E4.1.3.3; N-acetylneuraminate lyase [EC:4.1.3.3] D ShL2_00815 mnaA; UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D ShL2_00307 cap5P; capsular polysaccharide biosynthesis protein Cap5P K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D ShL2_00306 cap5O; capsular polysaccharide biosynthesis protein Cap5O K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336] D ShL2_00297 cap5E; capsular polysaccharide biosynthesis protein Cap5E K15894 pseB; UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase [EC:4.2.1.115 5.1.3.-] D ShL2_00272 PTS system maltose/glucose-specific IICB component K02791 malX; maltose/glucose PTS system EIICB component [EC:2.7.1.199 2.7.1.208] D ShL2_00417 PTS system, glucose-specific IICBA component K20118 ptsG; glucose PTS system EIICBA or EIICB component [EC:2.7.1.199] D ShL2_01252 glcK; glucokinase, ROK family K25026 glk; glucokinase [EC:2.7.1.2] D ShL2_00219 manB; phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D ShL2_00473 galU; UTP--glucose-1-phosphate uridylyltransferase subunit GalU K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D ShL2_01850 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D ShL2_00782 manA1; mannose-6 phosphate isomerase pmi K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] C 00620 Pyruvate metabolism [PATH:shh00620] D ShL2_01077 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D ShL2_00342 acsA2; AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D ShL2_01554 porA; pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D ShL2_01553 porB; 2-oxoglutarate ferredoxin oxidoreductase subunitbeta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D ShL2_01730 pdhA; pyruvate dehydrogenase E1 component subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D ShL2_01729 pdhB; pyruvate dehydrogenase E1 component subunit beta K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D ShL2_00149 bfmB_1; lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D ShL2_01728 pdhC; pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D ShL2_01727 pdhD_4; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00146 pdhD_2; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00150 pdhD_3; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_01281 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_01099 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D ShL2_02199 eutD; phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D ShL2_01112 pykA; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D ShL2_01110 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D ShL2_01194 accB_1; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit, Acc_B1 K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D ShL2_01272 accB_2; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D ShL2_01195 accC_1; acetyl-CoA carboxylase biotin carboxylase subunit, AccC_1 K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D ShL2_01273 accC_2; acetyl-CoA carboxylase accC (biotin carboxylase subunit) K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D ShL2_01109 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D ShL2_01387 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] D ShL2_00804 aldA; aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D ShL2_02157 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D ShL2_00415 cidC; thiamine pyrophosphate enzyme K00158 spxB; pyruvate oxidase [EC:1.2.3.3] D ShL2_00421 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D ShL2_00394 D-isomer specific 2-hydroxyacid dehydrogenase family protein K03778 ldhA; D-lactate dehydrogenase [EC:1.1.1.28] D ShL2_00440 D-lactate dehydrogenase K03778 ldhA; D-lactate dehydrogenase [EC:1.1.1.28] D ShL2_00447 gbsA_3; glycine betaine aldehyde dehydrogenase gbsA K07248 aldA; lactaldehyde dehydrogenase / glycolaldehyde dehydrogenase [EC:1.2.1.22 1.2.1.21] D ShL2_01254 metallo-beta-lactamase superfamily protein K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6] D ShL2_01108 maeB; malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] D ShL2_01708 pycA_1; pyruvate carboxylase K01958 PC; pyruvate carboxylase [EC:6.4.1.1] D ShL2_00592 mqo1; malate:quinone oxidoreductase 1 K00116 mqo; malate dehydrogenase (quinone) [EC:1.1.5.4] D ShL2_00348 mqo2; malate:quinone oxidoreductase 2 K00116 mqo; malate dehydrogenase (quinone) [EC:1.1.5.4] D ShL2_00995 fumC; fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2] D ShL2_01022 pckA; phosphoenolpyruvate carboxykinase K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] D ShL2_00346 ptsA_1; phosphoenolpyruvate-protein phosphotransferase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] D ShL2_02212 vraB; acetyl-CoA C-acetyltransferase VraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D ShL2_00408 paaJ; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D ShL2_00865 leuA; 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] C 00630 Glyoxylate and dicarboxylate metabolism [PATH:shh00630] D ShL2_01077 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D ShL2_00342 acsA2; AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D ShL2_01115 citZ; methylcitrate synthase K01647 CS; citrate synthase [EC:2.3.3.1] D ShL2_01435 citB; aconitate hydratase K01681 ACO; aconitate hydratase [EC:4.2.1.3] D ShL2_02212 vraB; acetyl-CoA C-acetyltransferase VraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D ShL2_00408 paaJ; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D ShL2_01450 katE; catalase K03781 katE; catalase [EC:1.11.1.6] D ShL2_01882 glyoxylate reductase K00015 gyaR; glyoxylate reductase [EC:1.1.1.26] D ShL2_02227 haloacid dehalogenase-like hydrolase K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18] D ShL2_01534 glnA; glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D ShL2_00813 glyA; serine hydroxymethyl transferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D ShL2_01264 gcvPA; glycine dehydrogenase, subunit 1 (glycine cleavage system P protein) K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2] D ShL2_01265 gcvPB; glycine dehydrogenase subunit 2 K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2] D ShL2_01263 gcvT; aminomethyltransferase (glycine cleavage system T protein) K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10] D ShL2_01727 pdhD_4; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00146 pdhD_2; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00150 pdhD_3; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_01281 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_01907 gcvH; glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein D ShL2_00530 glxK; glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D ShL2_02002 glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D ShL2_00447 gbsA_3; glycine betaine aldehyde dehydrogenase gbsA K07248 aldA; lactaldehyde dehydrogenase / glycolaldehyde dehydrogenase [EC:1.2.1.22 1.2.1.21] D ShL2_00648 molybdopterin oxidoreductase K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9] C 00640 Propanoate metabolism [PATH:shh00640] D ShL2_01077 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D ShL2_00342 acsA2; AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D ShL2_01099 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D ShL2_02199 eutD; phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D ShL2_01282 acoA_2; 2-oxoisovalerate dehydrogenase subunit alpha K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4] D ShL2_01283 bfmBAB_2; 2-oxoisovalerate dehydrogenase, E1 component, beta subunit K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4] D ShL2_01284 bfmB_2; lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168] D ShL2_01727 pdhD_4; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00146 pdhD_2; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00150 pdhD_3; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_01281 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00582 zinc-binding alcohol dehydrogenase K19745 acuI; acrylyl-CoA reductase (NADPH) [EC:1.3.1.-] D ShL2_01110 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D ShL2_01194 accB_1; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit, Acc_B1 K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D ShL2_01272 accB_2; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D ShL2_01195 accC_1; acetyl-CoA carboxylase biotin carboxylase subunit, AccC_1 K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D ShL2_01273 accC_2; acetyl-CoA carboxylase accC (biotin carboxylase subunit) K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D ShL2_01109 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D ShL2_00362 4-aminobutyrate aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D ShL2_01601 sucC; succinate--CoA ligase (ADP-forming) beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D ShL2_01600 sucD; succinate--CoA ligase (ADP-forming) alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D ShL2_00421 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] C 00650 Butanoate metabolism [PATH:shh00650] D ShL2_02212 vraB; acetyl-CoA C-acetyltransferase VraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D ShL2_00408 paaJ; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D ShL2_01683 sdhA; succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D ShL2_01682 sdhB; succinate dehydrogenase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D ShL2_01684 sdhC; succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 sdhC; succinate dehydrogenase cytochrome b subunit D ShL2_00362 4-aminobutyrate aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D ShL2_00138 gbsA_1; glycine betaine aldehyde dehydrogenase gbsA K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D ShL2_01554 porA; pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D ShL2_01553 porB; 2-oxoglutarate ferredoxin oxidoreductase subunitbeta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D ShL2_00407 mvaS; 3-hydroxy-3-methylglutaryl coenzyme A synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D ShL2_00418 zinc-binding alcohol dehydrogenase K18369 adh2; alcohol dehydrogenase [EC:1.1.1.-] D ShL2_00868 ilvB; acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D ShL2_00364 alsS; acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D ShL2_00867 acetolactate synthase 1 regulatory subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D ShL2_00365 budA1; alpha-acetolactate decarboxylase K01575 alsD; acetolactate decarboxylase [EC:4.1.1.5] D ShL2_00504 oxidoreductase, zinc-binding dehydrogenase family K00004 BDH; (R,R)-butanediol dehydrogenase / meso-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.4 1.1.1.- 1.1.1.303] C 00660 C5-Branched dibasic acid metabolism [PATH:shh00660] D ShL2_00868 ilvB; acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D ShL2_00364 alsS; acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D ShL2_00867 acetolactate synthase 1 regulatory subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D ShL2_00365 budA1; alpha-acetolactate decarboxylase K01575 alsD; acetolactate decarboxylase [EC:4.1.1.5] D ShL2_01601 sucC; succinate--CoA ligase (ADP-forming) beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D ShL2_01600 sucD; succinate--CoA ligase (ADP-forming) alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D ShL2_00863 leuC; 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D ShL2_00862 leuD; 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D ShL2_00864 leuB; 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] C 00562 Inositol phosphate metabolism [PATH:shh00562] D ShL2_01716 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D ShL2_00646 suhB_1; inositol monophosphatase family protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D ShL2_02436 suhB_2; inositol monophosphatase family protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D ShL2_01964 tpi; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] B B 09102 Energy metabolism C 00190 Oxidative phosphorylation [PATH:shh00190] D ShL2_01871 pyridine nucleotide-disulfide oxidoreductase K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9] D ShL2_01874 pyridine nucleotide-disulfide oxidoreductase K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9] D ShL2_01683 sdhA; succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D ShL2_01682 sdhB; succinate dehydrogenase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D ShL2_01684 sdhC; succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 sdhC; succinate dehydrogenase cytochrome b subunit D ShL2_01706 ctaB; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] D ShL2_01707 ctaA; cytochrome oxidase assembly protein K02259 COX15; heme a synthase [EC:1.17.99.9] D ShL2_01769 qoxD; quinol oxidase polypeptide IV QoxD K02829 qoxD; cytochrome aa3-600 menaquinol oxidase subunit IV [EC:7.1.1.5] D ShL2_01768 qoxC; Cytochrome aa3 quinol oxidase, subunit III K02828 qoxC; cytochrome aa3-600 menaquinol oxidase subunit III [EC:7.1.1.5] D ShL2_01767 qoxB; Cytochrome aa3 quinol oxidase, subunit I K02827 qoxB; cytochrome aa3-600 menaquinol oxidase subunit I [EC:7.1.1.5] D ShL2_01766 qoxA; quinol oxidase polypeptide II precursor K02826 qoxA; cytochrome aa3-600 menaquinol oxidase subunit II [EC:7.1.1.5] D ShL2_01738 cydB; Cytochrome bd-type quinol oxidase subunit 2-likeprotein K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7] D ShL2_00821 atpA_2; ATP synthase subunit alpha, AtpA K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D ShL2_00823 atpB_2; ATP synthase subunit beta, AtpB K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D ShL2_00822 atpG; ATP synthase subunit gamma, AtpG K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D ShL2_00820 atpD; ATP synthase subunit delta K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D ShL2_00824 atpE; ATP synthase epsilon chain, AtpE K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D ShL2_00817 atpA_1; ATP synthase subunit alpha, AtpA_1 K02108 ATPF0A; F-type H+-transporting ATPase subunit a D ShL2_00819 atpB_1; ATP synthase subunit beta, AtpB_1 K02109 ATPF0B; F-type H+-transporting ATPase subunit b D ShL2_00818 atpC; ATP synthase subunit C, AtpC K02110 ATPF0C; F-type H+-transporting ATPase subunit c D ShL2_00922 ppaC; manganese-dependent inorganic pyrophosphatase K15986 ppaC; manganese-dependent inorganic pyrophosphatase [EC:3.6.1.1] D ShL2_00485 ppk; Polyphosphate kinase K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] C 00195 Photosynthesis C 00196 Photosynthesis - antenna proteins C 00710 Carbon fixation in photosynthetic organisms C 00720 Carbon fixation pathways in prokaryotes C 00680 Methane metabolism [PATH:shh00680] D ShL2_00648 molybdopterin oxidoreductase K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9] D ShL2_00813 glyA; serine hydroxymethyl transferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D ShL2_01962 eno; enolase (2-phosphoglycerate dehydrogenase) K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D ShL2_00355 fdaB; fructose-bisphosphate aldolase K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D ShL2_00801 fbaA; tagatose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D ShL2_00454 fbp; fructose-1,6-bisphosphatase K04041 fbp3; fructose-1,6-bisphosphatase III [EC:3.1.3.11] D ShL2_01111 pfkA; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D ShL2_02214 6-phospho-3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27] D ShL2_02215 hxlA; 3-hexulose-6-phosphate synthase K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43] D ShL2_01099 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D ShL2_02199 eutD; phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D ShL2_01077 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D ShL2_00342 acsA2; AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D ShL2_00535 gpm; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D ShL2_02370 phosphoglycerate mutase family protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D ShL2_01963 pgm; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D ShL2_01087 serA; D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] C 00910 Nitrogen metabolism [PATH:shh00910] D ShL2_00554 narG; respiratory nitrate reductase subunit alpha K00370 narG; nitrate reductase / nitrite oxidoreductase, alpha subunit [EC:1.7.5.1 1.7.99.-] D ShL2_00555 narY; nitrate reductase subunit beta K00371 narH; nitrate reductase / nitrite oxidoreductase, beta subunit [EC:1.7.5.1 1.7.99.-] D ShL2_00557 narI; respiratory nitrate reductase subunit gamma K00374 narI; nitrate reductase gamma subunit [EC:1.7.5.1 1.7.99.-] D ShL2_00551 nirB; nitrite reductase, large subunit K26139 nasD; nitrite reductase [NAD(P)H] large subunit [EC:1.7.1.4] D ShL2_00552 nirD; nitrite reductase small subunit K26138 nasE; nitrite reductase [NAD(P)H] small subunit [EC:1.7.1.4] D ShL2_01891 2-nitropropane dioxygenase K00459 ncd2; nitronate monooxygenase [EC:1.13.12.16] D ShL2_01854 gudB; NAD-specific glutamate dehydrogenase K00260 gudB; glutamate dehydrogenase [EC:1.4.1.2] D ShL2_01534 glnA; glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D ShL2_02325 gltB; glutamate synthase (NADPH), large subunit K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] D ShL2_02324 gltD; glutamate synthase (NADPH) small subunit K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] D ShL2_00175 arcC1; carbamate kinase, ArcC1 K00926 arcC; carbamate kinase [EC:2.7.2.2] C 00920 Sulfur metabolism [PATH:shh00920] D ShL2_00326 sat; Sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4] D ShL2_00327 cysC; adenylyl-sulfate kinase K00860 cysC; adenylylsulfate kinase [EC:2.7.1.25] D ShL2_01106 exopolyphosphatase-like protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] D ShL2_00320 cysH; Phosphoadenosine phosphosulfate reductase K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] D ShL2_00321 cysJ; sulfite reductase (NADPH) flavoprotein alpha-component K00380 cysJ; sulfite reductase (NADPH) flavoprotein alpha-component [EC:1.8.1.2] D ShL2_00322 cysI; Sulfite reductase [NADPH] hemoprotein beta-component K00381 cysI; sulfite reductase (NADPH) hemoprotein beta-component [EC:1.8.1.2] D ShL2_02266 cysE; serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D ShL2_02283 cysK; cysteine synthase (o-acetylserine sulfhydrylase), CysK K01738 cysK; cysteine synthase [EC:2.5.1.47] D ShL2_00011 metX; homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46] D ShL2_02431 bifunctional cystathionine gamma-lyase/gamma-synthase K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48] D ShL2_02333 metB_2; bifunctional cystathionine gamma-lyase/gamma-synthase K17217 mccB; cystathionine gamma-lyase / homocysteine desulfhydrase [EC:4.4.1.1 4.4.1.2] B B 09103 Lipid metabolism C 00061 Fatty acid biosynthesis [PATH:shh00061] D ShL2_01110 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D ShL2_01194 accB_1; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit, Acc_B1 K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D ShL2_01272 accB_2; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D ShL2_01195 accC_1; acetyl-CoA carboxylase biotin carboxylase subunit, AccC_1 K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D ShL2_01273 accC_2; acetyl-CoA carboxylase accC (biotin carboxylase subunit) K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D ShL2_01109 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D ShL2_01614 acpP; acyl carrier protein K02078 acpP; acyl carrier protein D ShL2_01616 fabD; malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D ShL2_01836 fabH; 3-oxoacyl synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D ShL2_01835 fabB; 3-oxoacyl-(acyl carrier protein) synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D ShL2_01567 3-oxoacyl-acyl carrier protein reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D ShL2_01615 fabG_3; 3-oxoacyl-ACP reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D ShL2_00827 fabZ; (3R)-hydroxymyristoyl-ACP dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D ShL2_02408 fabI_2; enoyl-acyl-carrier-protein reductase, FabI K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] D ShL2_01809 fabI_1; enoyl-acyl-carrier-protein reductase, FabI K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] D ShL2_02213 vraA; long chain fatty acid CoA ligase, VraA K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 00062 Fatty acid elongation C 00071 Fatty acid degradation [PATH:shh00071] D ShL2_02212 vraB; acetyl-CoA C-acetyltransferase VraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D ShL2_00408 paaJ; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D ShL2_02213 vraA; long chain fatty acid CoA ligase, VraA K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D ShL2_00804 aldA; aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D ShL2_02157 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] C 00073 Cutin, suberine and wax biosynthesis C 00100 Steroid biosynthesis C 00120 Primary bile acid biosynthesis C 00121 Secondary bile acid biosynthesis C 00140 Steroid hormone biosynthesis C 00561 Glycerolipid metabolism [PATH:shh00561] D ShL2_00530 glxK; glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D ShL2_02002 glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D ShL2_00804 aldA; aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D ShL2_02157 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D ShL2_02092 dihydroxyacetone kinase family protein K05878 dhaK; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaK [EC:2.7.1.121] D ShL2_02091 dihydroxyacetone kinase, DhaL subunit K05879 dhaL; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaL [EC:2.7.1.121] D ShL2_02090 dhaM; dihydroxyacetone kinase, phosphotransfer subunit K05881 dhaM; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaM [EC:2.7.1.121] D ShL2_01543 glpK; glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30] D ShL2_01617 plsX; glycerol-3-phosphate acyltransferase PlsX K03621 plsX; phosphate acyltransferase [EC:2.3.1.274] D ShL2_01432 plsY; Glycerol-3-phosphate acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D ShL2_01084 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D ShL2_00941 lipid kinase K07029 dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107] D ShL2_00096 lip_1; triacylglycerol lipase K01046 lip; triacylglycerol lipase [EC:3.1.1.3] D ShL2_01804 ypfP; UDP-glucose diacylglycerol glucosyltransferase K03429 ugtP; processive 1,2-diacylglycerol beta-glucosyltransferase [EC:2.4.1.315] D ShL2_02027 phosphoglycerol transferase I K19005 ltaS; lipoteichoic acid synthase [EC:2.7.8.20] C 00564 Glycerophospholipid metabolism [PATH:shh00564] D ShL2_01322 gpsA; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94] D ShL2_01542 glpD; DNA-directed DNA polymerase III subunit gamma and tau K00111 glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] D ShL2_01432 plsY; Glycerol-3-phosphate acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D ShL2_01084 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D ShL2_02105 tagD; glycerol-3-phosphate cytidylyltransferase K00980 tagD; glycerol-3-phosphate cytidylyltransferase [EC:2.7.7.39] D ShL2_00941 lipid kinase K07029 dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107] D ShL2_01041 pldB; lysophospholipase K01048 pldB; lysophospholipase [EC:3.1.1.5] D ShL2_01702 glycerophosphodiester phosphodiesterase K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46] D ShL2_01090 glycerophosphoryl diester phosphodiesterase K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46] D ShL2_00031 ugpQ_1; glycerophosphoryl diester phosphodiesterase, UgpQ_1 K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46] D ShL2_01853 glpQ; glycerophosphoryl diester phosphodiesterase K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46] D ShL2_01586 cdsA; phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41] D ShL2_01564 pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K00995 pgsA; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5] D ShL2_00838 cls2; phospholipase D/Transphosphatidylase K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-] D ShL2_01467 cls1; phospholipase D/Transphosphatidylase K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-] D ShL2_00933 pcrB; glycerol-1-phosphate prenyltransferase K07094 pcrB; heptaprenylglyceryl phosphate synthase [EC:2.5.1.-] D ShL2_01981 acetyltransferase K24872 yvoF; heptaprenylglycerol acetyltransferase [EC:2.3.1.-] C 00565 Ether lipid metabolism C 00600 Sphingolipid metabolism C 00590 Arachidonic acid metabolism C 00591 Linoleic acid metabolism C 00592 alpha-Linolenic acid metabolism C 01040 Biosynthesis of unsaturated fatty acids B B 09104 Nucleotide metabolism C 00230 Purine metabolism [PATH:shh00230] D ShL2_01302 nudF; ADP-ribose pyrophosphatase, NudF K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] D ShL2_00790 drm; phosphopentomutase K01839 deoB; phosphopentomutase [EC:5.4.2.7] D ShL2_00219 manB; phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D ShL2_02296 prs; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D ShL2_01756 purF; amidophosphoribosyltransferase precursor K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D ShL2_01752 purD; phosphoribosylamine--glycine ligase PurD K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] D ShL2_01754 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D ShL2_01757 purL; phosphoribosylformylglycinamidine synthase II K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3] D ShL2_01759 purS; phosphoribosylformylglycinamidine synthase subunit PurS K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3] D ShL2_01758 purQ; phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D ShL2_01755 purM; phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] D ShL2_01761 purK; phosphoribosylaminoimidazole carboxylase ATPase subunit K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18] D ShL2_01762 purE; phosphoribosylaminoimidazole carboxylase catalytic subunit K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] D ShL2_01760 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] D ShL2_00931 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D ShL2_01753 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D ShL2_01168 apt; adenine phosphoribosyl transferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D ShL2_00787 deoD; purine nucleoside phosphorylase K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1] D ShL2_01660 multi-copper polyphenol oxidoreductase laccase K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4] D ShL2_02286 hpt; hypoxanthine-guanine phosphoribosyltransferase K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8] D ShL2_02358 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D ShL2_01328 ndk; nucleoside diphosphate kinase superfamily protein K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D ShL2_01680 deoxyribonucleotide triphosphate pyrophosphatase K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66] D ShL2_02360 xprT; xanthine phosphoribosyltransferase K03816 xpt; xanthine phosphoribosyltransferase [EC:2.4.2.22] D ShL2_02357 guaA; bifunctional GMP synthase/glutamine amidotransferase protein K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D ShL2_01447 guaC; GMP reductase K00364 guaC; GMP reductase [EC:1.7.1.7] D ShL2_01637 gmk; guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8] D ShL2_02013 nrdE; ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D ShL2_02012 nrdF; ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D ShL2_02225 deoxynucleoside kinase K15518 dgk; deoxyguanosine kinase [EC:2.7.1.113] D ShL2_01169 relA; GTP pyrophosphokinase, (p)ppGpp synthetase I, RelA K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D ShL2_00486 ppx; Exopolyphosphatase K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40] D ShL2_01814 GTP pyrophosphokinase K07816 E2.7.6.5; GTP pyrophosphokinase [EC:2.7.6.5] D ShL2_00465 GTP pyrophosphokinase K07816 E2.7.6.5; GTP pyrophosphokinase [EC:2.7.6.5] D ShL2_00016 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D ShL2_02226 deoxynucleoside kinase K15519 dck; deoxyadenosine/deoxycytidine kinase [EC:2.7.1.76 2.7.1.74] D ShL2_00234 ushA; 5'-nucleotidase K01119 cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase [EC:3.1.4.16 3.1.3.6] D ShL2_02238 sasH; LPXTG surface 5'-nucleotidase K08693 yfkN; 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase / 5'-nucleotidase [EC:3.1.4.16 3.1.3.6 3.1.3.5] D ShL2_01555 ABC superfamily ATP binding cassette transporter, binding protein K09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16] D ShL2_00722 adk; Nucleoside-triphosphate--adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D ShL2_00327 cysC; adenylyl-sulfate kinase K00860 cysC; adenylylsulfate kinase [EC:2.7.1.25] D ShL2_00326 sat; Sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4] D ShL2_00175 arcC1; carbamate kinase, ArcC1 K00926 arcC; carbamate kinase [EC:2.7.2.2] C 00240 Pyrimidine metabolism [PATH:shh00240] D ShL2_01643 carB; carbamoyl-phosphate synthase, pyrimidine-specific, large chain K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D ShL2_01644 pyrAA; carbamoyl-phosphate synthase, pyrimidine-specific, small chain K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D ShL2_01646 pyrB; aspartate carbamoyltransferase catalytic subunit K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D ShL2_01645 pyrC; dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3] D ShL2_00375 pyrD; dihydroorotate dehydrogenase K00226 pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1] D ShL2_01641 pyrE; orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] D ShL2_01642 pyrF; orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] D ShL2_01589 smbA; uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22] D ShL2_01328 ndk; nucleoside diphosphate kinase superfamily protein K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D ShL2_00799 ctrA; CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2] D ShL2_01319 cmk; cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25] D ShL2_01190 udk; uridine kinase K00876 udk; uridine kinase [EC:2.7.1.48] D ShL2_02238 sasH; LPXTG surface 5'-nucleotidase K08693 yfkN; 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase / 5'-nucleotidase [EC:3.1.4.16 3.1.3.6 3.1.3.5] D ShL2_00814 upp; uracil phosphoribosyl transferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9] D ShL2_01648 pyrR; bifunctional protein pyrimidine operon regulatory protein/uracil phosphoribosyltransferase, PyrR K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9] D ShL2_00234 ushA; 5'-nucleotidase K01119 cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase [EC:3.1.4.16 3.1.3.6] D ShL2_01555 ABC superfamily ATP binding cassette transporter, binding protein K09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16] D ShL2_00789 pdp; pyrimidine-nucleoside phosphorylase K00756 pdp; pyrimidine-nucleoside phosphorylase [EC:2.4.2.2] D ShL2_01230 cdd; cytidine deaminase K01489 cdd; cytidine deaminase [EC:3.5.4.5] D ShL2_02013 nrdE; ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D ShL2_02012 nrdF; ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D ShL2_02226 deoxynucleoside kinase K15519 dck; deoxyadenosine/deoxycytidine kinase [EC:2.7.1.76 2.7.1.74] D ShL2_01209 comEB; late competence operon required for DNA binding and uptake comEB K01493 comEB; dCMP deaminase [EC:3.5.4.12] D ShL2_02314 tmk; thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D ShL2_00807 tdk; thymidine kinase K00857 tdk; thymidine kinase [EC:2.7.1.21] D ShL2_01363 thyA; thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] B B 09105 Amino acid metabolism C 00250 Alanine, aspartate and glutamate metabolism [PATH:shh00250] D ShL2_01318 ansA; Alpha/beta hydrolase fold-3 domain-containing protein K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1] D ShL2_00886 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase K13566 NIT2; omega-amidase [EC:3.5.1.3] D ShL2_01101 ald; alanine dehydrogenase K00259 ald; alanine dehydrogenase [EC:1.4.1.1] D ShL2_01851 argG; argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D ShL2_01852 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D ShL2_00016 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D ShL2_00931 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D ShL2_01646 pyrB; aspartate carbamoyltransferase catalytic subunit K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D ShL2_00362 4-aminobutyrate aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D ShL2_00138 gbsA_1; glycine betaine aldehyde dehydrogenase gbsA K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D ShL2_02325 gltB; glutamate synthase (NADPH), large subunit K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] D ShL2_02324 gltD; glutamate synthase (NADPH) small subunit K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] D ShL2_01854 gudB; NAD-specific glutamate dehydrogenase K00260 gudB; glutamate dehydrogenase [EC:1.4.1.2] D ShL2_00400 rocA; 1-pyrroline-5-carboxylate dehydrogenase K00294 E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88] D ShL2_01534 glnA; glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D ShL2_01643 carB; carbamoyl-phosphate synthase, pyrimidine-specific, large chain K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D ShL2_01644 pyrAA; carbamoyl-phosphate synthase, pyrimidine-specific, small chain K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D ShL2_01758 purQ; phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D ShL2_00773 glmS; glucosamine--fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D ShL2_01756 purF; amidophosphoribosyltransferase precursor K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C 00260 Glycine, serine and threonine metabolism [PATH:shh00260] D ShL2_01457 thrA; aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D ShL2_01398 lysC; aspartokinase, alpha and beta subunits K00928 lysC; aspartate kinase [EC:2.7.2.4] D ShL2_01397 asd; aspartate semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D ShL2_01456 dhoM; homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D ShL2_01454 thrB; homoserine kinase, ThrB K00872 thrB; homoserine kinase [EC:2.7.1.39] D ShL2_01455 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D ShL2_01469 gLY1; aromatic amino acid beta-eliminating lyase/threonine aldolase K01620 ltaE; threonine aldolase [EC:4.1.2.48] D ShL2_00813 glyA; serine hydroxymethyl transferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D ShL2_00530 glxK; glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D ShL2_02002 glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D ShL2_00535 gpm; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D ShL2_02370 phosphoglycerate mutase family protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D ShL2_01963 pgm; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D ShL2_01087 serA; D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D ShL2_02242 kbl; pyridoxal phosphate-dependent acyltransferase K00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29] D ShL2_01264 gcvPA; glycine dehydrogenase, subunit 1 (glycine cleavage system P protein) K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2] D ShL2_01265 gcvPB; glycine dehydrogenase subunit 2 K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2] D ShL2_01263 gcvT; aminomethyltransferase (glycine cleavage system T protein) K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10] D ShL2_01727 pdhD_4; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00146 pdhD_2; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00150 pdhD_3; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_01281 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_01907 gcvH; glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein D ShL2_00335 betA; choline dehydrogenase K00108 betA; choline dehydrogenase [EC:1.1.99.1] D ShL2_00334 gbsA_2; glycine betaine aldehyde dehydrogenase gbsA K00130 betB; betaine-aldehyde dehydrogenase [EC:1.2.1.8] D ShL2_02333 metB_2; bifunctional cystathionine gamma-lyase/gamma-synthase K17217 mccB; cystathionine gamma-lyase / homocysteine desulfhydrase [EC:4.4.1.1 4.4.1.2] D ShL2_00434 sdaAB; L-serine dehydratase, iron-sulfur-dependent subunit beta K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] D ShL2_00435 sdaAA; L-serine dehydratase, iron-sulfur-dependent subunit alpha K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] D ShL2_00861 ilvA_1; threonine dehydratase biosynthetic, IlvA_1 K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19] D ShL2_01413 trpA; tryptophan synthase subunit alpha K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D ShL2_01414 trpB; tryptophan synthase subunit beta K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] C 00270 Cysteine and methionine metabolism [PATH:shh00270] D ShL2_02266 cysE; serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D ShL2_02283 cysK; cysteine synthase (o-acetylserine sulfhydrylase), CysK K01738 cysK; cysteine synthase [EC:2.5.1.47] D ShL2_02333 metB_2; bifunctional cystathionine gamma-lyase/gamma-synthase K17217 mccB; cystathionine gamma-lyase / homocysteine desulfhydrase [EC:4.4.1.1 4.4.1.2] D ShL2_02432 bifunctional cystathionine gamma-lyase/gamma-synthase K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D ShL2_00144 aromatic amino acid transferase K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D ShL2_02334 cysM; Cystathionine beta-synthase, CysM K17216 mccA; cystathionine beta-synthase (O-acetyl-L-serine) [EC:2.5.1.134] D ShL2_02433 metH; bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase K24042 yitJ; methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54] D ShL2_02434 metE; 5-methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D ShL2_01023 metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D ShL2_01198 pfs; bifunctional methylthioadenosine nucleosidase/adenosylhomocysteine nucleosidase K01243 mtnN; adenosylhomocysteine nucleosidase [EC:3.2.2.9] D ShL2_01660 multi-copper polyphenol oxidoreductase laccase K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4] D ShL2_00393 N-succinyldiaminopimelate aminotransferase K08969 mtnE; L-glutamine---4-(methylsulfanyl)-2-oxobutanoate aminotransferase [EC:2.6.1.117] D ShL2_01092 GAF domain-containing protein K08968 msrC; L-methionine (R)-S-oxide reductase [EC:1.8.4.14] D ShL2_00792 luxS; autoinducer-2 production protein LuxS K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21] D ShL2_01457 thrA; aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D ShL2_01398 lysC; aspartokinase, alpha and beta subunits K00928 lysC; aspartate kinase [EC:2.7.2.4] D ShL2_01397 asd; aspartate semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D ShL2_01456 dhoM; homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D ShL2_00011 metX; homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46] D ShL2_02431 bifunctional cystathionine gamma-lyase/gamma-synthase K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48] D ShL2_00491 metB_1; bifunctional cystathionine gamma-lyase/gamma-synthase K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49] D ShL2_02236 ilvE; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D ShL2_00421 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D ShL2_00434 sdaAB; L-serine dehydratase, iron-sulfur-dependent subunit beta K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] D ShL2_00435 sdaAA; L-serine dehydratase, iron-sulfur-dependent subunit alpha K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] D ShL2_01087 serA; D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] C 00280 Valine, leucine and isoleucine degradation [PATH:shh00280] D ShL2_02236 ilvE; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D ShL2_01282 acoA_2; 2-oxoisovalerate dehydrogenase subunit alpha K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4] D ShL2_01283 bfmBAB_2; 2-oxoisovalerate dehydrogenase, E1 component, beta subunit K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4] D ShL2_01284 bfmB_2; lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168] D ShL2_01727 pdhD_4; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00146 pdhD_2; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00150 pdhD_3; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_01281 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00804 aldA; aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D ShL2_02157 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D ShL2_02212 vraB; acetyl-CoA C-acetyltransferase VraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D ShL2_00408 paaJ; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D ShL2_00407 mvaS; 3-hydroxy-3-methylglutaryl coenzyme A synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] C 00290 Valine, leucine and isoleucine biosynthesis [PATH:shh00290] D ShL2_00861 ilvA_1; threonine dehydratase biosynthetic, IlvA_1 K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19] D ShL2_00863 leuC; 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D ShL2_00862 leuD; 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D ShL2_00864 leuB; 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] D ShL2_00868 ilvB; acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D ShL2_00364 alsS; acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D ShL2_00867 acetolactate synthase 1 regulatory subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D ShL2_00866 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D ShL2_00869 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D ShL2_02236 ilvE; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D ShL2_00865 leuA; 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] C 00300 Lysine biosynthesis [PATH:shh00300] D ShL2_01456 dhoM; homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D ShL2_01457 thrA; aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D ShL2_01398 lysC; aspartokinase, alpha and beta subunits K00928 lysC; aspartate kinase [EC:2.7.2.4] D ShL2_01397 asd; aspartate semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D ShL2_01396 dapA; dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D ShL2_01395 dapB; dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] D ShL2_00059 argE_1; succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D ShL2_01057 Peptidase family M20/M25/M40 K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D ShL2_02115 argE_3; succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D ShL2_01391 lysA; diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D ShL2_01394 dapD; tetrahydrodipicolinate N-acetyltransferase K05822 dapH; tetrahydrodipicolinate N-acetyltransferase [EC:2.3.1.89] D ShL2_01779 aromatic amino acid transferase K00841 patA; aminotransferase [EC:2.6.1.-] D ShL2_00845 murF; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] C 00310 Lysine degradation [PATH:shh00310] D ShL2_01377 odhB; dihydrolipoamide succinyltransferase E2 component of 2-oxoglutarate dehydrogenase complex K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61] D ShL2_01727 pdhD_4; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00146 pdhD_2; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00150 pdhD_3; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_01281 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_02212 vraB; acetyl-CoA C-acetyltransferase VraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D ShL2_00408 paaJ; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D ShL2_00138 gbsA_1; glycine betaine aldehyde dehydrogenase gbsA K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D ShL2_01058 dat; D-alanine aminotransferase K00824 dat; D-alanine transaminase [EC:2.6.1.21] D ShL2_00804 aldA; aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D ShL2_02157 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] C 00220 Arginine biosynthesis [PATH:shh00220] D ShL2_00174 argF; ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3] D ShL2_01851 argG; argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D ShL2_01852 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D ShL2_00280 arcA; arginine deiminase K01478 arcA; arginine deiminase [EC:3.5.3.6] D ShL2_00926 nitric-oxide synthase, oxygenase subunit K00491 nos; nitric-oxide synthase, bacterial [EC:1.14.14.47] D ShL2_01758 purQ; phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D ShL2_01534 glnA; glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D ShL2_01854 gudB; NAD-specific glutamate dehydrogenase K00260 gudB; glutamate dehydrogenase [EC:1.4.1.2] D ShL2_00175 arcC1; carbamate kinase, ArcC1 K00926 arcC; carbamate kinase [EC:2.7.2.2] C 00330 Arginine and proline metabolism [PATH:shh00330] D ShL2_00804 aldA; aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D ShL2_02157 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D ShL2_02316 ribosomal-protein-serine N-acetyltransferase K00657 speG; diamine N-acetyltransferase [EC:2.3.1.57] D ShL2_00926 nitric-oxide synthase, oxygenase subunit K00491 nos; nitric-oxide synthase, bacterial [EC:1.14.14.47] D ShL2_01855 rocD; ornithine--oxo-acid transaminase K00819 rocD; ornithine--oxo-acid transaminase [EC:2.6.1.13] D ShL2_01295 proC; pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2] D ShL2_01040 putA; proline dehydrogenase K00318 PRODH; proline dehydrogenase [EC:1.5.5.2] D ShL2_00400 rocA; 1-pyrroline-5-carboxylate dehydrogenase K00294 E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88] D ShL2_01058 dat; D-alanine aminotransferase K00824 dat; D-alanine transaminase [EC:2.6.1.21] C 00340 Histidine metabolism [PATH:shh00340] D ShL2_02020 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D ShL2_00623 hutG; formiminoglutamase K01479 hutG; formiminoglutamase [EC:3.5.3.8] D ShL2_00804 aldA; aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D ShL2_02157 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] C 00350 Tyrosine metabolism [PATH:shh00350] D ShL2_02020 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D ShL2_00138 gbsA_1; glycine betaine aldehyde dehydrogenase gbsA K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] C 00360 Phenylalanine metabolism [PATH:shh00360] D ShL2_02020 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D ShL2_01058 dat; D-alanine aminotransferase K00824 dat; D-alanine transaminase [EC:2.6.1.21] D ShL2_02366 amnF; 2-oxopent-4-enoate hydratase K02554 mhpD; 2-keto-4-pentenoate hydratase [EC:4.2.1.80] C 00380 Tryptophan metabolism [PATH:shh00380] D ShL2_01377 odhB; dihydrolipoamide succinyltransferase E2 component of 2-oxoglutarate dehydrogenase complex K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61] D ShL2_01727 pdhD_4; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00146 pdhD_2; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00150 pdhD_3; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_01281 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_02212 vraB; acetyl-CoA C-acetyltransferase VraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D ShL2_00408 paaJ; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D ShL2_00804 aldA; aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D ShL2_02157 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D ShL2_01450 katE; catalase K03781 katE; catalase [EC:1.11.1.6] C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:shh00400] D ShL2_01073 bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase K13853 aroG; 3-deoxy-7-phosphoheptulonate synthase / chorismate mutase [EC:2.5.1.54 5.4.99.5] D ShL2_01330 aroB; 3-dehydroquinate synthase K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4] D ShL2_01911 aroD; 3-dehydroquinate dehydratase K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10] D ShL2_01201 aroE; shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] D ShL2_01262 aroK; shikimate kinase, AroK K00891 aroK; shikimate kinase [EC:2.7.1.71] D ShL2_01331 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19] D ShL2_01329 aroC; chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5] D ShL2_01419 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D ShL2_01418 trpG; anthranilate synthase, glutamine amidotransferase, component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D ShL2_01417 trpD; anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18] D ShL2_01415 hypothetical protein K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24] D ShL2_01416 trpC; indole-3-glycerol phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48] D ShL2_01413 trpA; tryptophan synthase subunit alpha K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D ShL2_01414 trpB; tryptophan synthase subunit beta K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D ShL2_01160 hypothetical protein K06209 pheB; chorismate mutase [EC:5.4.99.5] D ShL2_01421 tyrA; prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12] D ShL2_00925 pheA; prephenate dehydratase K04518 pheA2; prephenate dehydratase [EC:4.2.1.51] D ShL2_02020 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] B B 09106 Metabolism of other amino acids C 00410 beta-Alanine metabolism [PATH:shh00410] D ShL2_00109 panD; low molecular weight phosphotyrosine protein phosphatase K01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11] D ShL2_00362 4-aminobutyrate aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D ShL2_00804 aldA; aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D ShL2_02157 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D ShL2_00108 panC; pantoate--beta-alanine ligase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1] C 00430 Taurine and hypotaurine metabolism [PATH:shh00430] D ShL2_00431 ggt; gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D ShL2_01101 ald; alanine dehydrogenase K00259 ald; alanine dehydrogenase [EC:1.4.1.1] D ShL2_01854 gudB; NAD-specific glutamate dehydrogenase K00260 gudB; glutamate dehydrogenase [EC:1.4.1.2] D ShL2_02199 eutD; phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D ShL2_01099 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] C 00440 Phosphonate and phosphinate metabolism C 00450 Selenocompound metabolism [PATH:shh00450] D ShL2_02431 bifunctional cystathionine gamma-lyase/gamma-synthase K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48] D ShL2_02432 bifunctional cystathionine gamma-lyase/gamma-synthase K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D ShL2_00144 aromatic amino acid transferase K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D ShL2_02433 metH; bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase K24042 yitJ; methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54] D ShL2_02434 metE; 5-methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D ShL2_01895 sufS; cysteine desulfurase, SufS subfamily K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16] D ShL2_01979 trxB; thioredoxin-disulfide reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9] D ShL2_00326 sat; Sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4] D ShL2_02306 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] C 00460 Cyanoamino acid metabolism [PATH:shh00460] D ShL2_00431 ggt; gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D ShL2_01318 ansA; Alpha/beta hydrolase fold-3 domain-containing protein K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1] D ShL2_00813 glyA; serine hydroxymethyl transferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] C 00470 D-Amino acid metabolism [PATH:shh00470] D ShL2_01392 alr2; alanine racemase family protein K01775 alr; alanine racemase [EC:5.1.1.1] D ShL2_00851 alr; alanine racemase 1 K01775 alr; alanine racemase [EC:5.1.1.1] D ShL2_01058 dat; D-alanine aminotransferase K00824 dat; D-alanine transaminase [EC:2.6.1.21] D ShL2_00844 ddl; D-alanyl-alanine synthetase A K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D ShL2_01879 dltC; D-alanine-activating enzyme/D-alanine-D-alanyl, dltC protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D ShL2_01758 purQ; phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D ShL2_01681 murI; glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3] D ShL2_01665 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D ShL2_01391 lysA; diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D ShL2_00755 alanine racemase K21898 orr; ornithine racemase [EC:5.1.1.12] C 00480 Glutathione metabolism [PATH:shh00480] D ShL2_00431 ggt; gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D ShL2_01196 lamB; LamB/YcsF family protein K07160 pxpA; 5-oxoprolinase (ATP-hydrolysing) subunit A [EC:3.5.2.9] D ShL2_01870 ampA; cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] D ShL2_00141 pdhD_1; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7] D ShL2_01116 citC; isocitrate dehydrogenase K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42] D ShL2_01289 gnd; 6-phosphogluconate dehydrogenase K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] D ShL2_01293 zwf; glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D ShL2_01538 bsaA; glutathione peroxidase K00432 gpx; glutathione peroxidase [EC:1.11.1.9] B B 09107 Glycan biosynthesis and metabolism C 00510 N-Glycan biosynthesis C 00513 Various types of N-glycan biosynthesis C 00512 Mucin type O-glycan biosynthesis C 00515 Mannose type O-glycan biosynthesis C 00514 Other types of O-glycan biosynthesis C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin C 00533 Glycosaminoglycan biosynthesis - keratan sulfate C 00531 Glycosaminoglycan degradation C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series C 00604 Glycosphingolipid biosynthesis - ganglio series C 00511 Other glycan degradation D ShL2_01775 atl; bifunctional N-acetylmuramoyl-L-alanine amidase/endo-beta-N-acetylglucosaminidase, Atl K13714 atl; bifunctional autolysin [EC:3.5.1.28 3.2.1.96] C 00540 Lipopolysaccharide biosynthesis C 00542 O-Antigen repeat unit biosynthesis [PATH:shh00542] D ShL2_01997 glycosyl transferase family protein K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] C 00541 O-Antigen nucleotide sugar biosynthesis [PATH:shh00541] D ShL2_00473 galU; UTP--glucose-1-phosphate uridylyltransferase subunit GalU K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D ShL2_00782 manA1; mannose-6 phosphate isomerase pmi K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] D ShL2_02297 gcaD; UDP-N-acetylglucosamine pyrophosphorylase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157] D ShL2_00815 mnaA; UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D ShL2_00307 cap5P; capsular polysaccharide biosynthesis protein Cap5P K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D ShL2_00306 cap5O; capsular polysaccharide biosynthesis protein Cap5O K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336] D ShL2_00297 cap5E; capsular polysaccharide biosynthesis protein Cap5E K15894 pseB; UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase [EC:4.2.1.115 5.1.3.-] D ShL2_00298 cap5F; capsular polysaccharide biosynthesis protein Cap5F K19068 wbjC; UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose reductase [EC:1.1.1.367] D ShL2_00299 cap5G; capsular polysaccharide biosynthesis protein Cap5G K24258 wbjD; UDP-N-acetyl-L-fucosamine synthase [EC:5.1.3.28] D ShL2_00296 cap5D; capsular polysaccharide biosynthesis protein Cap5D K24300 wbpM; UDP-N-acetylglucosamine 4,6-dehydratase [EC:4.2.1.135] C 00550 Peptidoglycan biosynthesis [PATH:shh00550] D ShL2_00802 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D ShL2_00826 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D ShL2_02006 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D ShL2_01069 murC; UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D ShL2_01665 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D ShL2_00844 ddl; D-alanyl-alanine synthetase A K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D ShL2_00845 murF; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D ShL2_01229 dgkA; diacylglycerol kinase K00887 dgkA; undecaprenol kinase [EC:2.7.1.66] D ShL2_01587 uppS; di-trans, poly-cis-decaprenylcistransferase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D ShL2_02058 bacA; bacitracin resistance protein, undecaprenyl pyrophosphate phosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D ShL2_01373 phosphoesterase, PA-phosphatase-like protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] D ShL2_01666 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D ShL2_01372 murG; N-acetylglucosaminyl transferase, MurG K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D ShL2_01345 pbp2; glycosyl transferase family protein K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D ShL2_00221 pbp4_1; serine-type D-Ala-D-Ala carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D ShL2_02104 pbp4_2; serine-type D-Ala-D-Ala carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D ShL2_00111 vanY; D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D ShL2_01803 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase K05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7] D ShL2_00947 murE2; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase K23393 murT; lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13] D ShL2_00948 adenosylcobyric acid synthase K07009 gatD; lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13] D ShL2_00689 fmhB; peptidoglycan pentaglycine interpeptide biosynthetic protein FmhB K11693 femX; peptidoglycan pentaglycine glycine transferase (the first glycine) [EC:2.3.2.16] D ShL2_01411 femA; glycine interpeptide bridge formation protein FemA K11694 femA; peptidoglycan pentaglycine glycine transferase (the second and third glycine) [EC:2.3.2.17] D ShL2_01410 femB; glycine interpeptide bridge formation protein FemB K11695 femB; peptidoglycan pentaglycine glycine transferase (the fourth and fifth glycine) [EC:2.3.2.18] D ShL2_01079 mrcB; membrane carboxypeptidase K12551 sgtA; monofunctional glycosyltransferase [EC:2.4.99.28] D ShL2_00969 sgtB; monofunctional glycosyltransferase K04478 sgtB; monofunctional glycosyltransferase [EC:2.4.99.28] D ShL2_01667 pbpA; penicillin-binding protein 1 K12552 pbpA; penicillin-binding protein 1 [EC:3.4.-.-] D ShL2_01247 pbp3; penicillin-binding protein 3 K12553 pbp3; penicillin-binding protein 3 [EC:3.4.-.-] D ShL2_00029 mecA; penicillin-binding protein 2 prime K02545 mecA; penicillin-binding protein 2 prime [EC:3.4.16.4] D ShL2_01599 fmhA_2; FemAB family peptidoglycan biosynthesis protein K12554 murN; alanine adding enzyme [EC:2.3.2.-] C 00552 Teichoic acid biosynthesis [PATH:shh00552] D ShL2_02058 bacA; bacitracin resistance protein, undecaprenyl pyrophosphate phosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D ShL2_01373 phosphoesterase, PA-phosphatase-like protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] D ShL2_01997 glycosyl transferase family protein K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D ShL2_02110 wecG; teichoic acid biosynthesis protein K05946 tagA; N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase [EC:2.4.1.187] D ShL2_02107 tagB; teichoic acid biosynthesis protein B K21285 tagB; teichoic acid glycerol-phosphate primase [EC:2.7.8.44] D ShL2_02098 tarF_3; CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase K09809 tagF; CDP-glycerol glycerophosphotransferase [EC:2.7.8.12] D ShL2_01879 dltC; D-alanine-activating enzyme/D-alanine-D-alanyl, dltC protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D ShL2_01880 dltB; D-alanine membrane transfer protein K03739 dltB; membrane protein involved in D-alanine export D ShL2_01878 dltD; D-alanine lipoteichoic acid and wall teichoic acid esterification secreted protein K03740 dltD; D-alanine transfer protein D ShL2_01424 msrR; cell envelope transcriptional attenuator K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-] D ShL2_01772 cell envelope transcriptional attenuator K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-] D ShL2_00647 cell envelope transcriptional attenuator K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-] D ShL2_00308 cell envelope transcriptional attenuator K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-] D ShL2_00067 glycosyl transferase family protein K22708 tarS; poly(ribitol-phosphate) beta-N-acetylglucosaminyltransferase [EC:2.4.1.355] D ShL2_01804 ypfP; UDP-glucose diacylglycerol glucosyltransferase K03429 ugtP; processive 1,2-diacylglycerol beta-glucosyltransferase [EC:2.4.1.315] D ShL2_02027 phosphoglycerol transferase I K19005 ltaS; lipoteichoic acid synthase [EC:2.7.8.20] D ShL2_02038 undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase K25617 csbB; lipoteichoic acid polyisoprenyl-phosphate beta-N-acetylglucosaminyltransferase [EC:2.4.-.-] D ShL2_01604 yfhO; membrane protein YfhO K25619 yfhO; lipoteichoic acid glycosylation protein D ShL2_00296 cap5D; capsular polysaccharide biosynthesis protein Cap5D K24300 wbpM; UDP-N-acetylglucosamine 4,6-dehydratase [EC:4.2.1.135] C 00571 Lipoarabinomannan (LAM) biosynthesis C 00572 Arabinogalactan biosynthesis - Mycobacterium C 00543 Exopolysaccharide biosynthesis [PATH:shh00543] D ShL2_01997 glycosyl transferase family protein K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D ShL2_02266 cysE; serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] B B 09108 Metabolism of cofactors and vitamins C 00730 Thiamine metabolism [PATH:shh00730] D ShL2_00832 thiD; phosphomethylpyrimidine kinase K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7] D ShL2_00456 thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein K03148 thiF; sulfur carrier protein ThiS adenylyltransferase [EC:2.7.7.73] D ShL2_01094 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D ShL2_01179 nifS; cysteine desulfurase, NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D ShL2_01095 thiI; thiamine biosynthesis protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D ShL2_00459 thiO; Glycine oxidase K03153 thiO; glycine oxidase [EC:1.4.3.19] D ShL2_00457 thiG; Thiazole synthase K03149 thiG; thiazole synthase [EC:2.8.1.10] D ShL2_00460 tenI; Regulatory protein TenI K10810 tenI; thiazole tautomerase (transcriptional regulator TenI) [EC:5.3.99.10] D ShL2_00833 thiM; hydroxyethylthiazole kinase K00878 thiM; hydroxyethylthiazole kinase [EC:2.7.1.50] D ShL2_00834 thiE; thiamine-phosphate pyrophosphorylase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3] D ShL2_01626 rsgA; ribosome small subunit-dependent GTPase A K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D ShL2_00309 phoA; alkaline phosphatase PhoA K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1] D ShL2_00722 adk; Nucleoside-triphosphate--adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D ShL2_00831 tenA; thiaminase-2 K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2] D ShL2_00484 argE_2; succinyl-diaminopimelate desuccinylase K20895 ylmB; formylaminopyrimidine deformylase [EC:3.5.1.-] C 00740 Riboflavin metabolism [PATH:shh00740] D ShL2_01038 ribA; bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25] D ShL2_01036 ribD; bifunctional pyrimidine reductase / riboflavin biosynthesis protein K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D ShL2_01841 haloacid dehalogenase-like hydrolase K21064 ycsE; 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:3.1.3.104] D ShL2_01039 ribH; 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78] D ShL2_01037 ribB; riboflavin synthase subunit alpha K00793 ribE; riboflavin synthase [EC:2.5.1.9] D ShL2_01575 ribC; bifunctional protein including riboflavin kinaseand FAD synthase K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2] D ShL2_02365 Nitroreductase family protein K19285 nfrA1; FMN reductase (NADPH) [EC:1.5.1.38] D ShL2_00833 thiM; hydroxyethylthiazole kinase K00878 thiM; hydroxyethylthiazole kinase [EC:2.7.1.50] D ShL2_01302 nudF; ADP-ribose pyrophosphatase, NudF K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] C 00750 Vitamin B6 metabolism [PATH:shh00750] D ShL2_02207 thiD1_1; phosphomethylpyrimidine kinase K00868 pdxK; pyridoxine kinase [EC:2.7.1.35] D ShL2_01455 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D ShL2_02276 pdxS; pyridoxal biosynthesis lyase K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6] D ShL2_02275 pyridoxine biosynthesis amidotransferase K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6] C 00760 Nicotinate and nicotinamide metabolism [PATH:shh00760] D ShL2_00927 nadC; nicotinate phosphoribosyltransferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21] D ShL2_00787 deoD; purine nucleoside phosphorylase K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1] D ShL2_02238 sasH; LPXTG surface 5'-nucleotidase K08693 yfkN; 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase / 5'-nucleotidase [EC:3.1.4.16 3.1.3.6 3.1.3.5] D ShL2_01203 nadD; nicotinate (nicotinamide) nucleotide adenylyltransferase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18] D ShL2_00928 nadE; NH(3)-dependent NAD+ synthetase K01916 nadE; NAD+ synthase [EC:6.3.1.5] D ShL2_00734 NAD-dependent deacetylase K12410 cobB; NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313] D ShL2_01813 ppnK; inorganic polyphosphate/ATP-NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23] D ShL2_00138 gbsA_1; glycine betaine aldehyde dehydrogenase gbsA K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] C 00770 Pantothenate and CoA biosynthesis [PATH:shh00770] D ShL2_00868 ilvB; acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D ShL2_00364 alsS; acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D ShL2_00867 acetolactate synthase 1 regulatory subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D ShL2_00866 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D ShL2_00869 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D ShL2_00107 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11] D ShL2_00106 panE; ketopantoate reductase K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169] D ShL2_00514 apbA; 2-dehydropantoate 2-reductase K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169] D ShL2_00108 panC; pantoate--beta-alanine ligase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1] D ShL2_00796 panK; pantothenate kinase K09680 PANK1_2_3; type II pantothenate kinase [EC:2.7.1.33] D ShL2_01635 coaBC; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5] D ShL2_01698 kdtB; lipopolysaccharide core biosynthesis protein KdtB K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3] D ShL2_01121 coaE; dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24] D ShL2_00850 acpS; 4'-phosphopantetheinyl transferase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7] D ShL2_02236 ilvE; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D ShL2_00109 panD; low molecular weight phosphotyrosine protein phosphatase K01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11] D ShL2_00804 aldA; aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D ShL2_02157 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] C 00780 Biotin metabolism [PATH:shh00780] D ShL2_01835 fabB; 3-oxoacyl-(acyl carrier protein) synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D ShL2_01567 3-oxoacyl-acyl carrier protein reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D ShL2_01615 fabG_3; 3-oxoacyl-ACP reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D ShL2_00827 fabZ; (3R)-hydroxymyristoyl-ACP dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D ShL2_02408 fabI_2; enoyl-acyl-carrier-protein reductase, FabI K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] D ShL2_01809 fabI_1; enoyl-acyl-carrier-protein reductase, FabI K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] D ShL2_00186 bioB; biotin synthase K01012 bioB; biotin synthase [EC:2.8.1.6] D ShL2_01339 birA; bifunctional biotin-(acetyl-CoA carboxylase) ligase / biotin operon repressor K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] C 00785 Lipoic acid metabolism [PATH:shh00785] D ShL2_01267 lipoate-protein ligase A family protein K23734 lipM; lipoyl(octanoyl) transferase [EC:2.3.1.181] D ShL2_01887 lipA; Lipoyl synthase, LipA K03644 lipA; lipoyl synthase [EC:2.8.1.8] D ShL2_02198 lplA2; lipoate-protein ligase A family protein K16869 lipL; octanoyl-[GcvH]:protein N-octanoyltransferase [EC:2.3.1.204] D ShL2_00179 lplA1; lipoyltransferase and lipoate-protein ligase K03800 lplA; lipoate---protein ligase [EC:6.3.1.20] D ShL2_01793 lipoyltransferase and lipoate-protein ligase K03800 lplA; lipoate---protein ligase [EC:6.3.1.20] D ShL2_01727 pdhD_4; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00146 pdhD_2; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00150 pdhD_3; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_01281 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_01730 pdhA; pyruvate dehydrogenase E1 component subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D ShL2_01729 pdhB; pyruvate dehydrogenase E1 component subunit beta K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D ShL2_00149 bfmB_1; lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D ShL2_01728 pdhC; pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D ShL2_01376 kgd; oxoglutarate dehydrogenase (succinyl-transferring) E1 K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] D ShL2_01377 odhB; dihydrolipoamide succinyltransferase E2 component of 2-oxoglutarate dehydrogenase complex K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61] D ShL2_01282 acoA_2; 2-oxoisovalerate dehydrogenase subunit alpha K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4] D ShL2_01283 bfmBAB_2; 2-oxoisovalerate dehydrogenase, E1 component, beta subunit K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4] D ShL2_01284 bfmB_2; lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168] D ShL2_01264 gcvPA; glycine dehydrogenase, subunit 1 (glycine cleavage system P protein) K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2] D ShL2_01265 gcvPB; glycine dehydrogenase subunit 2 K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2] D ShL2_01263 gcvT; aminomethyltransferase (glycine cleavage system T protein) K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10] D ShL2_01907 gcvH; glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein C 00790 Folate biosynthesis [PATH:shh00790] D ShL2_02218 GTP cyclohydrolase K09007 folE2; GTP cyclohydrolase IB [EC:3.5.4.16] D ShL2_00309 phoA; alkaline phosphatase PhoA K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1] D ShL2_02281 folB; dihydroneopterin aldolase K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81] D ShL2_02280 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] D ShL2_02282 folP; dihydropteroate synthase chain A synthetase K00796 folP; dihydropteroate synthase [EC:2.5.1.15] D ShL2_01364 dfrA_2; trimethoprim-sensitive dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D ShL2_01296 dfrA_1; trimethoprim-sensitive dihydrofolate reductase K18591 dfrD; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3] D ShL2_01147 folC; bifunctional folylpolyglutamate synthase/dihydrofolate synthase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] D ShL2_01038 ribA; bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25] D ShL2_02033 pabA; para-aminobenzoate synthase, glutamine amidotransferase, component II K01664 pabA; para-aminobenzoate synthetase component II [EC:2.6.1.85] D ShL2_02032 pabB; anthranilate synthase K01665 pabB; para-aminobenzoate synthetase component I [EC:2.6.1.85] D ShL2_02031 pabC; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase-like protein K02619 pabC; 4-amino-4-deoxychorismate lyase [EC:4.1.3.38] D ShL2_00084 6-pyruvoyl tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D ShL2_02035 6-pyruvoyl-tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D ShL2_02036 queE; 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] D ShL2_02034 queC; queuosine biosynthesis protein QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D ShL2_02016 folE; NADPH-dependent 7-cyano-7-deazaguanine reductase K09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13] D ShL2_00683 molybdenum cofactor biosynthesis protein A K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22] D ShL2_00677 moaC; molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] D ShL2_00680 moaE; Molybdopterin synthase catalytic subunit, MoaE K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12] D ShL2_00676 moaB; molybdenum cofactor biosynthesis protein B K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75] D ShL2_00678 moeA; molybdopterin biosynthesis protein MoeA K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1] D ShL2_00682 mobA; molybdopterin-guanine dinucleotide biosynthesis protein A K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77] C 00670 One carbon pool by folate [PATH:shh00670] D ShL2_01364 dfrA_2; trimethoprim-sensitive dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D ShL2_01296 dfrA_1; trimethoprim-sensitive dihydrofolate reductase K18591 dfrD; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3] D ShL2_01078 fhs; formyltetrahydrofolate synthetase K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3] D ShL2_01763 folD; bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase, FolD K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] D ShL2_00813 glyA; serine hydroxymethyl transferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D ShL2_01754 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D ShL2_01753 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D ShL2_01631 fmt; methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D ShL2_01263 gcvT; aminomethyltransferase (glycine cleavage system T protein) K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10] D ShL2_02433 metH; bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase K24042 yitJ; methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54] D ShL2_01363 thyA; thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] D ShL2_01249 5-formyltetrahydrofolate cyclo-ligase K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] C 00830 Retinol metabolism C 00860 Porphyrin metabolism [PATH:shh00860] D ShL2_01138 hemA; glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70] D ShL2_00983 gsaB; glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D ShL2_01143 hemL; glutamate-1-semialdehyde aminotransferase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D ShL2_01142 hemB; delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D ShL2_01140 hemC; hydroxymethylbilane synthase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61] D ShL2_01141 hemD; uroporphyrinogen III synthase HEM4 K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75] D ShL2_01013 hemE; uroporphyrinogen decarboxylase K01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37] D ShL2_01015 hemY; protoporphyrinogen oxidase K00231 PPOX; protoporphyrinogen/coproporphyrinogen III oxidase [EC:1.3.3.4 1.3.3.15] D ShL2_01014 hemH; ferrochelatase K01772 hemH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9] D ShL2_02200 heme peroxidase K00435 hemQ; hydrogen peroxide-dependent heme synthase [EC:1.3.98.5] D ShL2_00553 nasF_2; tetrapyrrole (corrin/porphyrin) methylase familyprotein K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107] D ShL2_00323 nasF_1; tetrapyrrole (corrin/porphyrin) methylase familyprotein K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107] D ShL2_00324 cysG; precorrin-2 dehydrogenase K24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76] D ShL2_00550 cbiX; sirohydrochlorin cobalt chelatase K03794 sirB; sirohydrochlorin ferrochelatase [EC:4.99.1.4] D ShL2_01706 ctaB; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] D ShL2_01707 ctaA; cytochrome oxidase assembly protein K02259 COX15; heme a synthase [EC:1.17.99.9] D ShL2_00760 isdI; heme-degrading monooxygenase IsdI K07145 isdG; heme oxygenase (staphylobilin-producing) [EC:1.14.99.48] C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:shh00130] D ShL2_01326 2-heptaprenyl-1,4-naphthoquinone methyltransferase K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201] D ShL2_01783 menF; salicylate biosynthesis isochorismate synthase K02552 menF; menaquinone-specific isochorismate synthase [EC:5.4.4.2] D ShL2_01782 menD; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase K02551 menD; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:2.2.1.9] D ShL2_01781 yfbB_2; acyl-CoA thioester hydrolase K08680 menH; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [EC:4.2.99.20] D ShL2_01018 NAAAR, N-acylamino acid racemase K02549 menC; o-succinylbenzoate synthase [EC:4.2.1.113] D ShL2_01017 O-succinylbenzoic acid--CoA ligase K01911 menE; o-succinylbenzoate---CoA ligase [EC:6.2.1.26] D ShL2_01780 menB; naphthoate synthase K01661 menB; naphthoate synthase [EC:4.1.3.36] D ShL2_01868 thioesterase superfamily protein K19222 menI; 1,4-dihydroxy-2-naphthoyl-CoA hydrolase [EC:3.1.2.28] D ShL2_01784 menA; DHNA-octaprenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74] D ShL2_00125 ywrO; General stress protein 14 K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2] D ShL2_00169 azoreductase K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2] B B 09109 Metabolism of terpenoids and polyketides C 00900 Terpenoid backbone biosynthesis [PATH:shh00900] D ShL2_02301 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase K00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148] D ShL2_02212 vraB; acetyl-CoA C-acetyltransferase VraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D ShL2_00408 paaJ; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D ShL2_00407 mvaS; 3-hydroxy-3-methylglutaryl coenzyme A synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D ShL2_00409 mvaA; hydroxymethylglutaryl-CoA reductase, degradative K00054 mvaA; hydroxymethylglutaryl-CoA reductase [EC:1.1.1.88] D ShL2_02197 mvaK1; mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36] D ShL2_02195 mvaK2_2; phosphomevalonate kinase K00938 E2.7.4.2; phosphomevalonate kinase [EC:2.7.4.2] D ShL2_02196 mvaD; mevalonate diphosphate decarboxylase K01597 MVD; diphosphomevalonate decarboxylase [EC:4.1.1.33] D ShL2_00612 fni; isopentenyl-diphosphate delta-isomerase K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2] D ShL2_01278 ispA; geranyltranstransferase K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29] D ShL2_01325 heptaprenyl diphosphate synthase subunit 1 K00805 hepS; heptaprenyl diphosphate synthase component 1 [EC:2.5.1.30] D ShL2_01327 gerCC; iron (Fe3+) ABC superfamily ATP binding cassettetransporter, membrane protein K24873 hepT; heptaprenyl diphosphate synthase component 2 [EC:2.5.1.30] D ShL2_01587 uppS; di-trans, poly-cis-decaprenylcistransferase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] C 00902 Monoterpenoid biosynthesis C 00909 Sesquiterpenoid and triterpenoid biosynthesis C 00904 Diterpenoid biosynthesis C 00906 Carotenoid biosynthesis [PATH:shh00906] D ShL2_00391 squalene/phytoene synthase K10208 crtM; 4,4'-diapophytoene synthase [EC:2.5.1.96] D ShL2_00392 crtN; dehydrosqualene desaturase K10209 crtN; 4,4'-diapophytoene desaturase [EC:1.3.8.2] D ShL2_00389 crtI; phytoene desaturase K10210 crtP; diapolycopene oxygenase [EC:1.14.99.44] D ShL2_00921 aldH; aldehyde dehydrogenase K25072 crtNc; 4,4'-diapolycopenoate synthase [EC:1.2.99.10] D ShL2_00390 glycosyl transferase family protein K10211 crtQ; 4,4'-diaponeurosporenoate glycosyltransferase [EC:2.4.1.-] C 00905 Brassinosteroid biosynthesis C 00981 Insect hormone biosynthesis C 00908 Zeatin biosynthesis C 00903 Limonene degradation D ShL2_00804 aldA; aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D ShL2_02157 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] C 00907 Pinene, camphor and geraniol degradation C 01052 Type I polyketide structures C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides C 01051 Biosynthesis of ansamycins D ShL2_01442 tktA; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] C 01059 Biosynthesis of enediyne antibiotics C 01056 Biosynthesis of type II polyketide backbone C 01057 Biosynthesis of type II polyketide products C 00253 Tetracycline biosynthesis C 00523 Polyketide sugar unit biosynthesis C 01054 Nonribosomal peptide structures C 01053 Biosynthesis of siderophore group nonribosomal peptides D ShL2_01783 menF; salicylate biosynthesis isochorismate synthase K02552 menF; menaquinone-specific isochorismate synthase [EC:5.4.4.2] C 01055 Biosynthesis of vancomycin group antibiotics B B 09110 Biosynthesis of other secondary metabolites C 00940 Phenylpropanoid biosynthesis C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis C 00941 Flavonoid biosynthesis C 00944 Flavone and flavonol biosynthesis C 00942 Anthocyanin biosynthesis C 00943 Isoflavonoid biosynthesis C 00946 Degradation of flavonoids C 00901 Indole alkaloid biosynthesis C 00403 Indole diterpene alkaloid biosynthesis C 00950 Isoquinoline alkaloid biosynthesis C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis C 00996 Biosynthesis of various alkaloids C 00232 Caffeine metabolism C 00965 Betalain biosynthesis C 00966 Glucosinolate biosynthesis C 00402 Benzoxazinoid biosynthesis C 00311 Penicillin and cephalosporin biosynthesis D ShL2_00215 penicillin V acylase K24041 yxeI; penicillin V amidase [EC:3.5.1.11] C 00332 Carbapenem biosynthesis C 00261 Monobactam biosynthesis [PATH:shh00261] D ShL2_00326 sat; Sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4] D ShL2_01457 thrA; aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D ShL2_01398 lysC; aspartokinase, alpha and beta subunits K00928 lysC; aspartate kinase [EC:2.7.2.4] D ShL2_01397 asd; aspartate semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D ShL2_01396 dapA; dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D ShL2_01395 dapB; dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] C 00331 Clavulanic acid biosynthesis C 00521 Streptomycin biosynthesis [PATH:shh00521] D ShL2_01252 glcK; glucokinase, ROK family K25026 glk; glucokinase [EC:2.7.1.2] D ShL2_00219 manB; phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D ShL2_01716 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D ShL2_00646 suhB_1; inositol monophosphatase family protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D ShL2_02436 suhB_2; inositol monophosphatase family protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] C 00524 Neomycin, kanamycin and gentamicin biosynthesis D ShL2_01252 glcK; glucokinase, ROK family K25026 glk; glucokinase [EC:2.7.1.2] C 00525 Acarbose and validamycin biosynthesis C 00401 Novobiocin biosynthesis [PATH:shh00401] D ShL2_01421 tyrA; prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12] D ShL2_02020 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] C 00404 Staurosporine biosynthesis C 00405 Phenazine biosynthesis D ShL2_01419 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D ShL2_01418 trpG; anthranilate synthase, glutamine amidotransferase, component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] C 00333 Prodigiosin biosynthesis D ShL2_01616 fabD; malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D ShL2_01567 3-oxoacyl-acyl carrier protein reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D ShL2_01615 fabG_3; 3-oxoacyl-ACP reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D ShL2_02408 fabI_2; enoyl-acyl-carrier-protein reductase, FabI K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] D ShL2_01809 fabI_1; enoyl-acyl-carrier-protein reductase, FabI K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] C 00254 Aflatoxin biosynthesis C 00998 Biosynthesis of various antibiotics D ShL2_01614 acpP; acyl carrier protein K02078 acpP; acyl carrier protein C 00999 Biosynthesis of various plant secondary metabolites [PATH:shh00999] D ShL2_01023 metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D ShL2_01201 aroE; shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] C 00997 Biosynthesis of various other secondary metabolites [PATH:shh00997] D ShL2_00755 alanine racemase K21898 orr; ornithine racemase [EC:5.1.1.12] D ShL2_00752 aerobactin biosynthesis protein, IucA/IucC family K23446 sfnaD; D-ornithine---citrate ligase [EC:6.3.2.58] D ShL2_00754 aerobactin biosynthesis protein, IucA/IucC family K23447 sfnaB; staphyloferrin A synthase [EC:6.3.2.57] B B 09111 Xenobiotics biodegradation and metabolism C 00362 Benzoate degradation [PATH:shh00362] D ShL2_01652 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2] D ShL2_00444 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2] D ShL2_02366 amnF; 2-oxopent-4-enoate hydratase K02554 mhpD; 2-keto-4-pentenoate hydratase [EC:4.2.1.80] D ShL2_01423 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] D ShL2_02212 vraB; acetyl-CoA C-acetyltransferase VraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D ShL2_00408 paaJ; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00627 Aminobenzoate degradation D ShL2_01387 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] C 00364 Fluorobenzoate degradation C 00625 Chloroalkane and chloroalkene degradation [PATH:shh00625] D ShL2_00804 aldA; aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D ShL2_02157 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] C 00361 Chlorocyclohexane and chlorobenzene degradation D ShL2_01652 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2] D ShL2_00444 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2] C 00623 Toluene degradation C 00622 Xylene degradation [PATH:shh00622] D ShL2_01652 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2] D ShL2_00444 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2] D ShL2_01423 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] D ShL2_02366 amnF; 2-oxopent-4-enoate hydratase K02554 mhpD; 2-keto-4-pentenoate hydratase [EC:4.2.1.80] C 00633 Nitrotoluene degradation C 00642 Ethylbenzene degradation C 00643 Styrene degradation D ShL2_01652 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2] D ShL2_00444 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2] C 00791 Atrazine degradation C 00930 Caprolactam degradation C 00363 Bisphenol degradation C 00621 Dioxin degradation [PATH:shh00621] D ShL2_01423 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] D ShL2_02366 amnF; 2-oxopent-4-enoate hydratase K02554 mhpD; 2-keto-4-pentenoate hydratase [EC:4.2.1.80] C 00626 Naphthalene degradation C 00624 Polycyclic aromatic hydrocarbon degradation C 00365 Furfural degradation C 00984 Steroid degradation C 00980 Metabolism of xenobiotics by cytochrome P450 C 00982 Drug metabolism - cytochrome P450 C 00983 Drug metabolism - other enzymes B B 09112 Not included in regular maps C 09113 Global maps only # A09120 Genetic Information Processing B B 09121 Transcription C 03020 RNA polymerase [PATH:shh03020] D ShL2_02251 rpoB_1; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D ShL2_02250 rpoC; DNA-directed RNA polymerase beta' chain protein K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D ShL2_00727 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D ShL2_01636 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D ShL2_00798 rpoE; DNA-directed RNA polymerase subunit delta K03048 rpoE; DNA-directed RNA polymerase subunit delta C 03022 Basal transcription factors C 03040 Spliceosome B B 09122 Translation C 03010 Ribosome [PATH:shh03010] D ShL2_01320 rpsA; 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1 D ShL2_01591 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D ShL2_00707 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D ShL2_01091 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D ShL2_00718 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D ShL2_02424 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6 D ShL2_02247 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D ShL2_00715 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D ShL2_00733 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D ShL2_00700 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D ShL2_00726 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D ShL2_02248 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D ShL2_00725 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D ShL2_00714 rpsN_1; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D ShL2_01448 rpsN_2; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D ShL2_01574 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D ShL2_01608 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16 D ShL2_00710 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D ShL2_02422 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18 D ShL2_00705 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D ShL2_01213 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20 D ShL2_01223 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21 D ShL2_02257 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D ShL2_00704 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D ShL2_00701 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D ShL2_00702 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4 D ShL2_00713 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D ShL2_00716 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D ShL2_02254 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12 D ShL2_00014 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9 D ShL2_02255 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D ShL2_02258 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D ShL2_00732 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D ShL2_00711 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D ShL2_00720 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D ShL2_00708 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16 D ShL2_00728 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17 D ShL2_00717 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D ShL2_01605 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19 D ShL2_01131 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20 D ShL2_01156 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21 D ShL2_00706 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D ShL2_00703 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D ShL2_00712 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D ShL2_02295 rplY; 50S ribosomal protein L25 Ctc-form K02897 RP-L25; large subunit ribosomal protein L25 D ShL2_01158 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27 D ShL2_01623 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28 D ShL2_00709 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D ShL2_00719 rpmD; 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30 D ShL2_00806 rpmE2; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31 D ShL2_01695 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32 D ShL2_01449 rpmG_2; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D ShL2_01248 rpmG_1; 50S ribosomal protein L33 type 1 K02913 RP-L33; large subunit ribosomal protein L33 D ShL2_01130 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35 D ShL2_00724 rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36 D ShL2_02249 ribosomal protein L7Ae-like protein K07590 RP-L7A; large subunit ribosomal protein L7A D ShL2_r00001 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D ShL2_r00012 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D ShL2_r00016 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D ShL2_r00007 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D ShL2_r00004 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D ShL2_r00005 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D ShL2_r00011 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D ShL2_r00002 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D ShL2_r00008 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D ShL2_r00015 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D ShL2_r00003 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D ShL2_r00006 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D ShL2_r00013 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D ShL2_r00010 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D ShL2_r00009 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D ShL2_r00014 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA C 00970 Aminoacyl-tRNA biosynthesis [PATH:shh00970] D ShL2_t00012 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D ShL2_t00052 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D ShL2_t00021 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D ShL2_t00047 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D ShL2_t00019 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D ShL2_t00054 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D ShL2_t00050 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D ShL2_t00003 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D ShL2_t00048 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D ShL2_t00044 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D ShL2_t00025 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D ShL2_t00028 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D ShL2_t00040 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D ShL2_t00002 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D ShL2_t00035 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D ShL2_t00007 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D ShL2_t00034 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D ShL2_t00045 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D ShL2_t00001 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D ShL2_t00004 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D ShL2_t00017 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D ShL2_t00056 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D ShL2_t00010 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D ShL2_t00043 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D ShL2_t00036 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D ShL2_t00037 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D ShL2_t00042 tRNA-His K14226 tRNA-His; tRNA His D ShL2_t00033 tRNA-His K14226 tRNA-His; tRNA His D ShL2_t00011 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D ShL2_t00051 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D ShL2_t00018 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D ShL2_t00055 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D ShL2_t00016 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D ShL2_t00038 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D ShL2_t00009 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D ShL2_t00008 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D ShL2_t00015 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D ShL2_t00057 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D ShL2_t00027 tRNA-Met K14230 tRNA-Met; tRNA Met D ShL2_t00039 tRNA-Met K14230 tRNA-Met; tRNA Met D ShL2_t00023 tRNA-Met K14230 tRNA-Met; tRNA Met D ShL2_t00022 tRNA-Met K14230 tRNA-Met; tRNA Met D ShL2_t00029 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D ShL2_t00041 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D ShL2_t00020 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D ShL2_t00053 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D ShL2_t00026 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D ShL2_t00060 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D ShL2_t00024 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D ShL2_t00049 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D ShL2_t00046 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D ShL2_t00014 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D ShL2_t00030 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D ShL2_t00058 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D ShL2_t00032 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D ShL2_t00006 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D ShL2_t00031 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D ShL2_t00005 tRNA-Val K14237 tRNA-Val; tRNA Val D ShL2_t00059 tRNA-Val K14237 tRNA-Val; tRNA Val D ShL2_t00013 tRNA-Val K14237 tRNA-Val; tRNA Val D ShL2_02267 gltX; glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24] D ShL2_00939 gatA; Aspartyl/glutamyl-tRNA amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D ShL2_00940 gatB; Aspartyl/glutamyl-tRNA amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D ShL2_00938 gatC; bifunctional aspartyl/glutamyl-tRNA amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D ShL2_01183 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D ShL2_01173 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D ShL2_01341 asnC; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D ShL2_01233 glyS; glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D ShL2_00061 thrS_1; threonyl-tRNA synthetase 1 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D ShL2_01127 thrS_2; threonyl-tRNA synthetase 1 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D ShL2_00008 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D ShL2_02265 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D ShL2_02306 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D ShL2_01631 fmt; methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D ShL2_01146 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D ShL2_01047 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D ShL2_01654 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D ShL2_02279 lysS; asparaginyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D ShL2_02142 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D ShL2_01584 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D ShL2_01172 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D ShL2_01693 pheS; phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D ShL2_01692 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D ShL2_01080 tyrS; tyrosyl-tRNA synthetase, TyrS K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D ShL2_01823 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] C 03013 Nucleocytoplasmic transport C 03015 mRNA surveillance pathway C 03008 Ribosome biogenesis in eukaryotes B B 09123 Folding, sorting and degradation C 03060 Protein export [PATH:shh03060] D ShL2_00721 secY_2; Sec family Type I general secretory pathway preprotein translocase SecY_1 K03076 secY; preprotein translocase subunit SecY D ShL2_00246 secY_1; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D ShL2_02260 secE; preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE D ShL2_01960 secG; preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG D ShL2_01166 secF; RND superfamily resistance-nodulation-cell division protein:proton (H+) antiporter K12257 secDF; SecD/SecF fusion protein D ShL2_01165 yajC; Sec family Type I general secretory pathway preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC D ShL2_00835 oxaI_2; OxaI/YidC membrane insertion protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D ShL2_00518 oxaI_1; OxaI/YidC membrane insertion protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D ShL2_00249 secA2; Sec family Type I general secretory pathway protein SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D ShL2_01991 secA; Sec family Type I general secretory pathway preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D ShL2_01609 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D ShL2_01611 ftsY; cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor D ShL2_00587 tatA; twin-arginine translocation protein, TatA/E family subunit K03116 tatA; sec-independent protein translocase protein TatA D ShL2_00586 tatC_1; Sec-independent periplasmic protein translocase K03118 tatC; sec-independent protein translocase protein TatC D ShL2_02443 Sec family Type I general secretory pathway S26 family signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D ShL2_01847 Sec family Type I general secretory pathway S26 family signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D ShL2_01848 lepB; Sec family Type I general secretory pathway S26 family signal peptidase I, LepB K03100 lepB; signal peptidase I [EC:3.4.21.89] D ShL2_01650 lspA; lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] C 04141 Protein processing in endoplasmic reticulum C 04130 SNARE interactions in vesicular transport C 04120 Ubiquitin mediated proteolysis C 04122 Sulfur relay system [PATH:shh04122] D ShL2_01094 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D ShL2_01179 nifS; cysteine desulfurase, NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D ShL2_01180 trmU; tRNA (5-methyl aminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D ShL2_00680 moaE; Molybdopterin synthase catalytic subunit, MoaE K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12] D ShL2_00683 molybdenum cofactor biosynthesis protein A K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22] D ShL2_00681 moaD; Mmolybdopterin converting factor, subunit 1 K03636 moaD; sulfur-carrier protein D ShL2_00675 thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein K21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80] D ShL2_00677 moaC; molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] D ShL2_00676 moaB; molybdenum cofactor biosynthesis protein B K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75] D ShL2_01095 thiI; thiamine biosynthesis protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D ShL2_00458 thiS; Sulfur carrier protein ThiS K03154 thiS; sulfur carrier protein D ShL2_00456 thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein K03148 thiF; sulfur carrier protein ThiS adenylyltransferase [EC:2.7.7.73] C 03050 Proteasome C 03018 RNA degradation [PATH:shh03018] D ShL2_01962 eno; enolase (2-phosphoglycerate dehydrogenase) K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D ShL2_01573 pnpA; polynucleotide phosphorylase/polyadenylase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D ShL2_01958 rnr; exoribonuclease, VacB/RNase II family K12573 rnr; ribonuclease R [EC:3.1.13.1] D ShL2_00846 ATP-dependent RNA helicase DEAD box family protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D ShL2_01314 recQ; ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] D ShL2_02024 ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] D ShL2_00805 rho; methicillin resistance expression factor K03628 rho; transcription termination factor Rho D ShL2_01557 phosphodiesterase K18682 rny; ribonucrease Y [EC:3.1.-.-] D ShL2_01734 mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) K12574 rnj; ribonuclease J [EC:3.1.-.-] D ShL2_01572 metallo-beta-lactamase family protein K12574 rnj; ribonuclease J [EC:3.1.-.-] D ShL2_01111 pfkA; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D ShL2_01218 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK D ShL2_00891 groEL; co-chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D ShL2_01539 hfq; RNA chaperone, host factor-1 protein K03666 hfq; host factor-I protein D ShL2_00485 ppk; Polyphosphate kinase K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] B B 09124 Replication and repair C 03030 DNA replication [PATH:shh03030] D ShL2_00945 Exonuclease, RNase T and DNA polymerase III K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D ShL2_01107 dnaE; DNA-directed DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D ShL2_01583 polC; DNA polymerase III subunit alpha K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D ShL2_02319 dnaX; DNA-directed DNA polymerase III subunit gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D ShL2_02312 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D ShL2_01211 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D ShL2_00002 dnaN; DNA-directed DNA polymerase beta subunit, DnaN K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D ShL2_00015 dnaC; replicative DNA helicase DnaB K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D ShL2_01236 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D ShL2_00829 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D ShL2_02423 ssb; ssDNA-binding protein K03111 ssb; single-strand DNA-binding protein D ShL2_01522 ssDNA-binding protein K03111 ssb; single-strand DNA-binding protein D ShL2_01358 cell wall enzyme EbsB-like protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4] D ShL2_01602 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D ShL2_01691 rnhC; ribonuclease HIII K03471 rnhC; ribonuclease HIII [EC:3.1.26.4] D ShL2_01119 DNA-directed DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D ShL2_00935 lig; DNA ligase (polydeoxyribonucleotide syntase) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03410 Base excision repair [PATH:shh03410] D ShL2_01343 nth; DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D ShL2_02206 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D ShL2_00978 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D ShL2_00614 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] D ShL2_01120 fpg; formamidopyrimidine-DNA glycosidase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] D ShL2_01145 tag; DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] D ShL2_01241 nfo; deoxyribonuclease IV (phage-T(4)-induced) K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D ShL2_01119 DNA-directed DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D ShL2_01167 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D ShL2_00935 lig; DNA ligase (polydeoxyribonucleotide syntase) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03420 Nucleotide excision repair [PATH:shh03420] D ShL2_02293 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D ShL2_01984 uvrA_2; excision endonuclease subunit UvrA K03701 uvrA; excinuclease ABC subunit A D ShL2_01985 uvrB; excision endonuclease subunit UvrB K03702 uvrB; excinuclease ABC subunit B D ShL2_00934 pcrA; ATP-dependent DNA helicase, PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D ShL2_01119 DNA-directed DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D ShL2_00935 lig; DNA ligase (polydeoxyribonucleotide syntase) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03430 Mismatch repair [PATH:shh03430] D ShL2_01547 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS D ShL2_01687 recombination and DNA strand exchange inhibitor protein K07456 mutS2; DNA mismatch repair protein MutS2 D ShL2_01546 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL D ShL2_00934 pcrA; ATP-dependent DNA helicase, PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D ShL2_01276 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D ShL2_01277 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D ShL2_01167 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D ShL2_00829 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D ShL2_02423 ssb; ssDNA-binding protein K03111 ssb; single-strand DNA-binding protein D ShL2_01522 ssDNA-binding protein K03111 ssb; single-strand DNA-binding protein D ShL2_01107 dnaE; DNA-directed DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D ShL2_01583 polC; DNA polymerase III subunit alpha K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D ShL2_00002 dnaN; DNA-directed DNA polymerase beta subunit, DnaN K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D ShL2_02319 dnaX; DNA-directed DNA polymerase III subunit gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D ShL2_01211 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D ShL2_02312 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D ShL2_00945 Exonuclease, RNase T and DNA polymerase III K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D ShL2_00935 lig; DNA ligase (polydeoxyribonucleotide syntase) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03440 Homologous recombination [PATH:shh03440] D ShL2_01167 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D ShL2_00829 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D ShL2_02423 ssb; ssDNA-binding protein K03111 ssb; single-strand DNA-binding protein D ShL2_01522 ssDNA-binding protein K03111 ssb; single-strand DNA-binding protein D ShL2_00004 recF; DNA repair and genetic recombination protein K03629 recF; DNA replication and repair protein RecF D ShL2_01232 recO; recombinational DNA repair protein (RecF pathway) K03584 recO; DNA repair protein RecO (recombination protein O) D ShL2_02317 recR; recombination protein K06187 recR; recombination protein RecR D ShL2_01562 recA; recombination protein RecA K03553 recA; recombination protein RecA D ShL2_01119 DNA-directed DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D ShL2_01161 ruvA; crossover junction endodeoxyribonuclease K03550 ruvA; holliday junction DNA helicase RuvA D ShL2_01162 ruvB; crossover junction endodeoxyribonuclease K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D ShL2_01619 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D ShL2_01182 recD; exodeoxyribonuclease V subunit alpha K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] D ShL2_01107 dnaE; DNA-directed DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D ShL2_01583 polC; DNA polymerase III subunit alpha K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D ShL2_00002 dnaN; DNA-directed DNA polymerase beta subunit, DnaN K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D ShL2_02319 dnaX; DNA-directed DNA polymerase III subunit gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D ShL2_01211 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D ShL2_02312 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D ShL2_00945 Exonuclease, RNase T and DNA polymerase III K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D ShL2_01634 priA; primosomal protein N prime K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] C 03450 Non-homologous end-joining C 03460 Fanconi anemia pathway B B 09126 Chromosome C 03082 ATP-dependent chromatin remodeling C 03083 Polycomb repressive complex B B 09125 Information processing in viruses C 03230 Viral genome structure C 03240 Viral replication C 03250 Viral life cycle - HIV-1 C 03260 Virion - Human immunodeficiency virus C 03271 Virion - Rotavirus C 03262 Virion - Coronavirus C 03261 Virion - Influenza virus C 03263 Virion - Enterovirus C 03264 Virion - Flavivirus C 03265 Virion - Ebolavirus and Lyssavirus C 03266 Virion - Herpesvirus C 03268 Virion - Orthopoxvirus C 03267 Virion - Adenovirus C 03259 Virion - Bacteriophages T4 and T7 C 03258 Virion - Bacteriophage lambda # A09130 Environmental Information Processing B B 09131 Membrane transport C 02010 ABC transporters [PATH:shh02010] D ShL2_00671 modA; molybdenum (Mo2+) ABC superfamily ATP binding cassette transporter, binding protein K02020 modA; molybdate transport system substrate-binding protein D ShL2_00672 modB; molybdenum (Mo2+) ABC superfamily ATP binding cassette transporter, membrane protein K02018 modB; molybdate transport system permease protein D ShL2_00674 modC_2; molybdenum (Mo2+) ABC superfamily ATP binding cassette transporter, ABC protein K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5] D ShL2_01721 potD; spermidine/putrescine ABC superfamily ATP binding cassette transporter, binding protein K11069 potD; spermidine/putrescine transport system substrate-binding protein D ShL2_01722 potC; binding-protein-dependent transport system innermembrane protein K11070 potC; spermidine/putrescine transport system permease protein D ShL2_01723 potB; binding-protein-dependent transport system innermembrane protein K11071 potB; spermidine/putrescine transport system permease protein D ShL2_01724 potA; putrescine/spermidine ABC transporter ATPase K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11] D ShL2_00265 gbuC; Glycine betaine/carnitine transport binding protein GbuC precursor K02002 proX; glycine betaine/proline transport system substrate-binding protein D ShL2_00507 opuCC; glycine betaine/L-proline ABC superfamily ATP binding cassette transporter, binding protein K05845 opuC; osmoprotectant transport system substrate-binding protein D ShL2_02022 ABC-type proline/glycine betaine transport systems, permease component K05845 opuC; osmoprotectant transport system substrate-binding protein D ShL2_00506 opuCB; glycine betaine/choline ABC superfamily ATP binding cassette transporter, membrane protein K05846 opuBD; osmoprotectant transport system permease protein D ShL2_00508 opuCD; glycine betaine/L-proline ABC superfamily ATP binding cassette transporter, membrane protein K05846 opuBD; osmoprotectant transport system permease protein D ShL2_00505 opuCA; glycine betaine/choline ABC superfamily ATP binding cassette transporter, ABC protein K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9] D ShL2_00105 rbsR_1; sugar-binding transcriptional regulator, LacI K10439 rbsB; ribose transport system substrate-binding protein D ShL2_00104 rbsC; Ribose transport system permease protein RbsC K10440 rbsC; ribose transport system permease protein D ShL2_00103 ABC transporter ATP-binding protein K10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7] D ShL2_00102 rbsD; ribose ABC superfamily ATP binding cassette transporter, membrane protein K06726 rbsD; D-ribose pyranase [EC:5.4.99.62] D ShL2_01401 pstS; phosphate ABC transporter periplasmic protein K02040 pstS; phosphate transport system substrate-binding protein D ShL2_01402 pstC; phosphate ABC superfamily ATP binding cassette transporter, membrane protein K02037 pstC; phosphate transport system permease protein D ShL2_01403 pstA; phosphate ABC superfamily ATP binding cassette transporter, membrane protein K02038 pstA; phosphate transport system permease protein D ShL2_01404 pstB; phosphate ABC superfamily ATP binding cassette transporter, ABC protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D ShL2_00235 phnD_1; phosphate/phosphonate ABC transporter periplasmic protein K02044 phnD; phosphonate transport system substrate-binding protein D ShL2_00443 phnD_2; phosphate/phosphonate ABC transporter periplasmic protein K02044 phnD; phosphonate transport system substrate-binding protein D ShL2_00237 ABC superfamily ATP binding cassette transporter, membrane protein K02042 phnE; phosphonate transport system permease protein D ShL2_00238 ABC superfamily ATP binding cassette transporter, membrane protein K02042 phnE; phosphonate transport system permease protein D ShL2_00236 phnC; phosphonate ABC transporter ATP-binding protein K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2] D ShL2_00538 amino acid ABC superfamily ATP binding cassette transporter, binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D ShL2_00539 ABC transporter ATP-binding protein K10009 tcyB; L-cystine transport system permease protein D ShL2_00540 ABC superfamily ATP binding cassette transporter, ABC protein K10010 tcyC; L-cystine transport system ATP-binding protein [EC:7.4.2.1] D ShL2_00988 polar amino acid ABC transporter inner membrane subunit K17077 artQ; arginine/lysine/histidine transport system permease protein D ShL2_00989 glnQ; glutamate ABC superfamily ATP binding cassette transporter, ABC protein K23060 artR; arginine/lysine/histidine transport system ATP-binding protein [EC:7.4.2.1] D ShL2_01902 ABC superfamily ATP binding cassette transporter, binding protein K02073 metQ; D-methionine transport system substrate-binding protein D ShL2_00361 ABC superfamily ATP binding cassette transporter, binding protein K02073 metQ; D-methionine transport system substrate-binding protein D ShL2_01903 binding-protein-dependent transport system innermembrane protein K02072 metI; D-methionine transport system permease protein D ShL2_01904 DL-methionine transporter ATP-binding subunit K02071 metN; D-methionine transport system ATP-binding protein D ShL2_01829 opp3A; oligopeptide ABC superfamily ATP binding cassette transporter, binding protein, Opp3A K15580 oppA; oligopeptide transport system substrate-binding protein D ShL2_01833 oppB; oligopeptide ABC superfamily ATP binding cassette transporter, membrane protein K15581 oppB; oligopeptide transport system permease protein D ShL2_01832 oppC; oligopeptide ABC superfamily ATP binding cassette transporter, membrane protein K15582 oppC; oligopeptide transport system permease protein D ShL2_01831 oppD; oligopeptide ABC superfamily ATP binding cassette transporter, ABC protein K15583 oppD; oligopeptide transport system ATP-binding protein D ShL2_01830 oppF; oligopeptide ABC superfamily ATP binding cassette transporter, ABC protein K10823 oppF; oligopeptide transport system ATP-binding protein D ShL2_00756 fecB; iron-dicitrate transporter substrate-binding subunit, FecB K23181 fecB; ferric citrate transport system substrate-binding protein D ShL2_00758 htsC; iron (Fe3+) ABC superfamily ATP binding cassettetransporter, membrane protein K23182 fecD; ferric citrate transport system permease protein D ShL2_00757 iron compound ABC transporter permease K23183 fecC; ferric citrate transport system permease protein D ShL2_00068 mntC; ABC superfamily ATP binding cassette transporter, binding protein K19975 mntC; manganese transport system substrate-binding protein D ShL2_00069 mntB; ABC superfamily ATP binding cassette transporter, membrane protein K19976 mntB; manganese transport system permease protein D ShL2_00070 mntA; ABC superfamily ATP binding cassette transporter, ABC protein K19973 mntA; manganese transport system ATP-binding protein [EC:7.2.2.5] D ShL2_00545 ABC superfamily ATP binding cassette transporter, binding protein K09815 znuA; zinc transport system substrate-binding protein D ShL2_00054 ABC superfamily ATP binding cassette transporter, binding protein K09815 znuA; zinc transport system substrate-binding protein D ShL2_00446 ABC superfamily ATP binding cassette transporter, binding protein K09815 znuA; zinc transport system substrate-binding protein D ShL2_01243 mreB; ABC superfamily ATP binding cassette transporter, membrane protein K09816 znuB; zinc transport system permease protein D ShL2_01242 znuC; zinc ABC transporter K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D ShL2_00668 biotin biosynthesis BioY family protein K03523 bioY; biotin transport system substrate-specific component D ShL2_01751 ykoC; ABC superfamily ATP binding cassette transporter, membrane protein K16785 ecfT; energy-coupling factor transport system permease protein D ShL2_00730 cobalt (Co2+) ABC superfamily ATP binding cassette transporter, membrane protein K16785 ecfT; energy-coupling factor transport system permease protein D ShL2_02108 tagG; teichoic acid ABC superfamily ATP binding cassette transporter, membrane protein K09692 tagG; teichoic acid transport system permease protein D ShL2_00974 ABC-type polysaccharide/polyol phosphate transport system ATPase component-like protein K09693 tagH; teichoic acid transport system ATP-binding protein [EC:7.5.2.4] D ShL2_02109 tagH; Teichoic acid export ATP-binding protein, TagH K09693 tagH; teichoic acid transport system ATP-binding protein [EC:7.5.2.4] D ShL2_00599 hemin import ATP-binding protein K09814 hrtA; hemin transport system ATP-binding protein [EC:7.6.2.-] D ShL2_02446 vraE; ABC transporter permease protein, involved in vancomycin resistance K11632 bceB; bacitracin transport system permease protein D ShL2_02445 vraD; SalX, ABC-type antimicrobial peptide transport system, involved in vancomycin resistance K11631 bceA; bacitracin transport system ATP-binding protein D ShL2_00315 ABC superfamily ATP binding cassette transporter, membrane protein K19084 braE; bacitracin transport system permease protein D ShL2_00314 ABC transporter ATP-binding protein K19083 braD; bacitracin transport system ATP-binding protein D ShL2_02081 permease K19080 vraG; cationic antimicrobial peptide transport system permease protein D ShL2_02082 antimicrobial peptide ABC transporter ATPase K19079 vraF; cationic antimicrobial peptide transport system ATP-binding protein D ShL2_02102 abcA; ABC superfamily ATP binding cassette transporter, ABC protein K18104 abcA; ATP-binding cassette, subfamily B, bacterial AbcA/BmrA [EC:7.6.2.2] D ShL2_02056 ABC superfamily ATP binding cassette transporter, ABC protein K16012 cydC; ATP-binding cassette, subfamily C, bacterial CydC D ShL2_02057 ABC superfamily ATP binding cassette transporter, ABC protein K16013 cydD; ATP-binding cassette, subfamily C, bacterial CydD D ShL2_02152 ABC transporter ATP-binding protein K18231 msr; macrolide transport system ATP-binding/permease protein C 02060 Phosphotransferase system (PTS) [PATH:shh02060] D ShL2_01743 ptsA_2; phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] D ShL2_01744 phosphocarrier protein Hpr K02784 ptsH; phosphocarrier protein HPr D ShL2_00417 PTS system, glucose-specific IICBA component K20118 ptsG; glucose PTS system EIICBA or EIICB component [EC:2.7.1.199] D ShL2_01368 crr; phosphotransferase system glucose-specific IIA component K02777 crr; sugar PTS system EIIA component [EC:2.7.1.-] D ShL2_01085 ptaA; phosphotransferase system, N-acetylglucosamine-specific IIBC component K02804 nagE; N-acetylglucosamine PTS system EIICBA or EIICB component [EC:2.7.1.193] D ShL2_00272 PTS system maltose/glucose-specific IICB component K02791 malX; maltose/glucose PTS system EIICB component [EC:2.7.1.199 2.7.1.208] D ShL2_00571 PTS system sucrose-specific IIBC component K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211] D ShL2_00641 murP; N-acetylmuramic acid phosphotransfer permease K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211] D ShL2_00632 PTS system glucose-specific IIBC component K02750 glvC; alpha-glucoside PTS system EIICB component [EC:2.7.1.208 2.7.1.-] D ShL2_02323 PTS system trehalose-specific IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D ShL2_00153 mtlA; PTS system mannitol-specific IIBC component K02800 mtlA; mannitol PTS system EIICBA or EIICB component [EC:2.7.1.197] D ShL2_00741 PTS system lactose/cellobiose-specific IIA component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207] D ShL2_00742 PTS system lactose/cellobiose-specific IIBC component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207] D ShL2_00115 PTS system lactose/cellobiose-specific IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D ShL2_00113 licB; Lichenan-specific phosphotransferase enzyme IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D ShL2_00114 PTS system lactose/cellobiose-specific IIBC component K02761 celB; cellobiose PTS system EIIC component D ShL2_02042 PTS system D-fructose-specific transporter subunit IIABC K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] D ShL2_02043 pfkB; fructose 1-phosphate kinase K00882 fruK; 1-phosphofructokinase [EC:2.7.1.56] C 03070 Bacterial secretion system [PATH:shh03070] D ShL2_01166 secF; RND superfamily resistance-nodulation-cell division protein:proton (H+) antiporter K12257 secDF; SecD/SecF fusion protein D ShL2_02260 secE; preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE D ShL2_01960 secG; preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG D ShL2_00721 secY_2; Sec family Type I general secretory pathway preprotein translocase SecY_1 K03076 secY; preprotein translocase subunit SecY D ShL2_00246 secY_1; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D ShL2_01165 yajC; Sec family Type I general secretory pathway preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC D ShL2_00835 oxaI_2; OxaI/YidC membrane insertion protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D ShL2_00518 oxaI_1; OxaI/YidC membrane insertion protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D ShL2_00249 secA2; Sec family Type I general secretory pathway protein SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D ShL2_01991 secA; Sec family Type I general secretory pathway preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D ShL2_01611 ftsY; cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor D ShL2_01609 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D ShL2_00587 tatA; twin-arginine translocation protein, TatA/E family subunit K03116 tatA; sec-independent protein translocase protein TatA D ShL2_00586 tatC_1; Sec-independent periplasmic protein translocase K03118 tatC; sec-independent protein translocase protein TatC B B 09132 Signal transduction C 02020 Two-component system [PATH:shh02020] D ShL2_01118 phoR; alkaline phosphatase synthesis sensor protein PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D ShL2_01117 ompR; response regulator OmpR K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP D ShL2_00309 phoA; alkaline phosphatase PhoA K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1] D ShL2_01401 pstS; phosphate ABC transporter periplasmic protein K02040 pstS; phosphate transport system substrate-binding protein D ShL2_01083 Trypsin-like serine endoprotease K04771 degP; serine protease Do [EC:3.4.21.107] D ShL2_01310 srrB_2; integral membrane sensor signal transduction histidine kinase K07651 resE; two-component system, OmpR family, sensor histidine kinase ResE [EC:2.7.13.3] D ShL2_01309 srrA_2; winged helix family two component transcriptional regulator K07775 resD; two-component system, OmpR family, response regulator ResD D ShL2_01707 ctaA; cytochrome oxidase assembly protein K02259 COX15; heme a synthase [EC:1.17.99.9] D ShL2_00018 walK; multi-sensor signal transduction histidine kinase, WalK K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3] D ShL2_00017 walR; transcriptional regulator WalR K07668 vicR; two-component system, OmpR family, response regulator VicR D ShL2_00001 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein D ShL2_02445 vraD; SalX, ABC-type antimicrobial peptide transport system, involved in vancomycin resistance K11631 bceA; bacitracin transport system ATP-binding protein D ShL2_02446 vraE; ABC transporter permease protein, involved in vancomycin resistance K11632 bceB; bacitracin transport system permease protein D ShL2_00315 ABC superfamily ATP binding cassette transporter, membrane protein K19084 braE; bacitracin transport system permease protein D ShL2_00314 ABC transporter ATP-binding protein K19083 braD; bacitracin transport system ATP-binding protein D ShL2_00313 integral membrane sensor signal transduction histidine kinase K19081 braS; two-component system, OmpR family, sensor histidine kinase BraS/BceS [EC:2.7.13.3] D ShL2_00312 winged helix family two component transcriptional regulator K19082 braR; two-component system, OmpR family, response regulator protein BraR/BceR D ShL2_02081 permease K19080 vraG; cationic antimicrobial peptide transport system permease protein D ShL2_02082 antimicrobial peptide ABC transporter ATPase K19079 vraF; cationic antimicrobial peptide transport system ATP-binding protein D ShL2_02083 graS; sensor histidine kinase, GraS K19077 graS; two-component system, OmpR family, sensor histidine kinase GraS [EC:2.7.13.3] D ShL2_02084 graR; winged helix family two component transcriptional regulator K19078 graR; two-component system, OmpR family, response regulator protein GraR D ShL2_01880 dltB; D-alanine membrane transfer protein K03739 dltB; membrane protein involved in D-alanine export D ShL2_01879 dltC; D-alanine-activating enzyme/D-alanine-D-alanyl, dltC protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D ShL2_01878 dltD; D-alanine lipoteichoic acid and wall teichoic acid esterification secreted protein K03740 dltD; D-alanine transfer protein D ShL2_01426 fmtC; oxacillin resistance-related FmtC protein K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3] D ShL2_00111 vanY; D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D ShL2_01375 arlS; signal transduction histidine kinase K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3] D ShL2_01374 arlR_2; response regulator receiver K18941 arlR; two-component system, OmpR family, response regulator ArlR D ShL2_01859 kapB; kinase associated protein B K06347 kapB; kinase-associated protein B D ShL2_01108 maeB; malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] D ShL2_00511 lytR; two component transcriptional regulator, LytR K07705 lytT; two-component system, LytTR family, response regulator LytT D ShL2_00510 lrgA_2; murein hydrolase regulator K05338 lrgA; holin-like protein D ShL2_00509 lrgB_2; antiholin-like protein LrgB K05339 lrgB; holin-like protein LrgB D ShL2_00885 agrB; accessory gene regulator B K07813 agrB; accessory gene regulator B D ShL2_00884 agrD; staphylococcal accessory gene regulator protein D K07800 agrD; AgrD protein D ShL2_00883 accessory gene regulator protein C K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D ShL2_00882 agrA; autoinducer sensor protein response regulator protein K07707 agrA; two-component system, LytTR family, response regulator AgrA D ShL2_00554 narG; respiratory nitrate reductase subunit alpha K00370 narG; nitrate reductase / nitrite oxidoreductase, alpha subunit [EC:1.7.5.1 1.7.99.-] D ShL2_00555 narY; nitrate reductase subunit beta K00371 narH; nitrate reductase / nitrite oxidoreductase, beta subunit [EC:1.7.5.1 1.7.99.-] D ShL2_00557 narI; respiratory nitrate reductase subunit gamma K00374 narI; nitrate reductase gamma subunit [EC:1.7.5.1 1.7.99.-] D ShL2_00556 narJ; nitrate reductase molybdenum cofactor assembly chaperone K00373 narJ; nitrate reductase molybdenum cofactor assembly chaperone NarJ/NarW D ShL2_01464 sensor histidine kinase K07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3] D ShL2_01463 response regulator K07693 desR; two-component system, NarL family, response regulator DesR D ShL2_00957 vraS; integral membrane sensor signal transduction histidine kinase K07681 vraS; two-component system, NarL family, vancomycin resistance sensor histidine kinase VraS [EC:2.7.13.3] D ShL2_00958 vraR; LuxR family two component transcriptional regulator K07694 vraR; two-component system, NarL family, vancomycin resistance associated response regulator VraR D ShL2_00559 nreB; oxygen sensor histidine kinase nreB K07683 nreB; two-component system, NarL family, sensor histidine kinase NreB [EC:2.7.13.3] D ShL2_00560 nreC; LuxR family two component transcriptional regulator K07696 nreC; two-component system, NarL family, response regulator NreC D ShL2_00558 hypothetical protein K10851 nreA; nitrogen regulatory protein A D ShL2_00561 narK; MFS family major facilitator transporter, nitrate:nitrite antiporter K10850 narT; MFS transporter, NNP family, putative nitrate transporter D ShL2_01534 glnA; glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D ShL2_02212 vraB; acetyl-CoA C-acetyltransferase VraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D ShL2_00408 paaJ; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D ShL2_01738 cydB; Cytochrome bd-type quinol oxidase subunit 2-likeprotein K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7] D ShL2_00961 phosphotyrosine protein phosphatase K25307 wzb; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48] D ShL2_00815 mnaA; UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D ShL2_00307 cap5P; capsular polysaccharide biosynthesis protein Cap5P K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D ShL2_00306 cap5O; capsular polysaccharide biosynthesis protein Cap5O K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336] C 04010 MAPK signaling pathway C 04013 MAPK signaling pathway - fly C 04016 MAPK signaling pathway - plant C 04011 MAPK signaling pathway - yeast C 04012 ErbB signaling pathway C 04014 Ras signaling pathway C 04015 Rap1 signaling pathway C 04310 Wnt signaling pathway C 04330 Notch signaling pathway C 04340 Hedgehog signaling pathway C 04341 Hedgehog signaling pathway - fly C 04350 TGF-beta signaling pathway C 04390 Hippo signaling pathway C 04391 Hippo signaling pathway - fly C 04392 Hippo signaling pathway - multiple species C 04370 VEGF signaling pathway C 04371 Apelin signaling pathway C 04630 JAK-STAT signaling pathway C 04064 NF-kappa B signaling pathway C 04668 TNF signaling pathway C 04066 HIF-1 signaling pathway C 04068 FoxO signaling pathway C 04020 Calcium signaling pathway C 04070 Phosphatidylinositol signaling system C 04072 Phospholipase D signaling pathway C 04071 Sphingolipid signaling pathway C 04024 cAMP signaling pathway C 04022 cGMP-PKG signaling pathway C 04151 PI3K-Akt signaling pathway C 04152 AMPK signaling pathway C 04150 mTOR signaling pathway C 04075 Plant hormone signal transduction B B 09133 Signaling molecules and interaction C 04080 Neuroactive ligand-receptor interaction C 04060 Cytokine-cytokine receptor interaction C 04061 Viral protein interaction with cytokine and cytokine receptor C 04512 ECM-receptor interaction C 04514 Cell adhesion molecules # A09140 Cellular Processes B B 09141 Transport and catabolism C 04144 Endocytosis C 04145 Phagosome C 04142 Lysosome C 04146 Peroxisome C 04140 Autophagy - animal C 04138 Autophagy - yeast C 04136 Autophagy - other C 04137 Mitophagy - animal C 04139 Mitophagy - yeast C 04148 Efferocytosis B B 09143 Cell growth and death C 04110 Cell cycle C 04111 Cell cycle - yeast C 04112 Cell cycle - Caulobacter C 04113 Meiosis - yeast C 04114 Oocyte meiosis C 04210 Apoptosis C 04214 Apoptosis - fly C 04215 Apoptosis - multiple species C 04216 Ferroptosis C 04217 Necroptosis C 04115 p53 signaling pathway C 04218 Cellular senescence B B 09144 Cellular community - eukaryotes C 04510 Focal adhesion C 04520 Adherens junction C 04530 Tight junction C 04540 Gap junction C 04550 Signaling pathways regulating pluripotency of stem cells B B 09145 Cellular community - prokaryotes C 02024 Quorum sensing [PATH:shh02024] D ShL2_00792 luxS; autoinducer-2 production protein LuxS K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21] D ShL2_01539 hfq; RNA chaperone, host factor-1 protein K03666 hfq; host factor-I protein D ShL2_01419 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D ShL2_01418 trpG; anthranilate synthase, glutamine amidotransferase, component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D ShL2_00285 metallo-beta-lactamase family protein K13075 ahlD; N-acyl homoserine lactone hydrolase [EC:3.1.1.81] D ShL2_01355 hypothetical protein K20276 bapA; large repetitive protein D ShL2_02213 vraA; long chain fatty acid CoA ligase, VraA K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D ShL2_01036 ribD; bifunctional pyrimidine reductase / riboflavin biosynthesis protein K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D ShL2_02128 hypothetical protein K09936 TC.BAT2; bacterial/archaeal transporter family-2 protein D ShL2_00884 agrD; staphylococcal accessory gene regulator protein D K07800 agrD; AgrD protein D ShL2_00885 agrB; accessory gene regulator B K07813 agrB; accessory gene regulator B D ShL2_00883 accessory gene regulator protein C K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D ShL2_00882 agrA; autoinducer sensor protein response regulator protein K07707 agrA; two-component system, LytTR family, response regulator AgrA D ShL2_01677 antibacterial protein (phenol soluble modulin) K20337 psmB; phenol-soluble modulin beta D ShL2_01678 antibacterial protein (phenol soluble modulin) K20337 psmB; phenol-soluble modulin beta D ShL2_01676 antibacterial protein (phenol soluble modulin) K20337 psmB; phenol-soluble modulin beta D ShL2_01675 antibacterial protein (phenol soluble modulin) K20337 psmB; phenol-soluble modulin beta D ShL2_01674 antibacterial protein (phenol soluble modulin) K20337 psmB; phenol-soluble modulin beta D ShL2_01043 rot; repressor of toxins, Rot K20338 rot; MarR family transcriptional regulator, global regulator for virulence D ShL2_01829 opp3A; oligopeptide ABC superfamily ATP binding cassette transporter, binding protein, Opp3A K15580 oppA; oligopeptide transport system substrate-binding protein D ShL2_01833 oppB; oligopeptide ABC superfamily ATP binding cassette transporter, membrane protein K15581 oppB; oligopeptide transport system permease protein D ShL2_01832 oppC; oligopeptide ABC superfamily ATP binding cassette transporter, membrane protein K15582 oppC; oligopeptide transport system permease protein D ShL2_01831 oppD; oligopeptide ABC superfamily ATP binding cassette transporter, ABC protein K15583 oppD; oligopeptide transport system ATP-binding protein D ShL2_01830 oppF; oligopeptide ABC superfamily ATP binding cassette transporter, ABC protein K10823 oppF; oligopeptide transport system ATP-binding protein D ShL2_00074 opp-1A_1; oligopeptide ABC superfamily ATP binding cassette transporter, binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D ShL2_00210 opp-1A_2; oligopeptide ABC superfamily ATP binding cassette transporter, binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D ShL2_00209 opp-2B_2; oligopeptide ABC superfamily ATP binding cassette transporter, membrane protein K02033 ABC.PE.P; peptide/nickel transport system permease protein D ShL2_00075 opp-2B_1; oligopeptide ABC superfamily ATP binding cassette transporter, membrane protein K02033 ABC.PE.P; peptide/nickel transport system permease protein D ShL2_00076 opp-2C_1; oligopeptide ABC superfamily ATP binding cassette transporter, membrane protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein D ShL2_00208 opp-2C_2; oligopeptide ABC superfamily ATP binding cassette transporter, membrane protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein D ShL2_00207 opp-1D_2; oligopeptide ABC superfamily ATP binding cassette transporter, ABC protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D ShL2_00077 opp-1D_1; oligopeptide ABC superfamily ATP binding cassette transporter, ABC protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D ShL2_00078 ABC superfamily ATP binding cassette transporter, ABC protein K02032 ddpF; peptide/nickel transport system ATP-binding protein D ShL2_00740 lacD; tagatose 1,6-diphosphate aldolase K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40] D ShL2_00835 oxaI_2; OxaI/YidC membrane insertion protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D ShL2_00518 oxaI_1; OxaI/YidC membrane insertion protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D ShL2_00097 splF; Serine protease SplF precursor K01318 sspA; glutamyl endopeptidase [EC:3.4.21.19] D ShL2_01789 comK; competence transcription factor ComK K02250 comK; competence protein ComK D ShL2_01166 secF; RND superfamily resistance-nodulation-cell division protein:proton (H+) antiporter K12257 secDF; SecD/SecF fusion protein D ShL2_02260 secE; preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE D ShL2_01960 secG; preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG D ShL2_00721 secY_2; Sec family Type I general secretory pathway preprotein translocase SecY_1 K03076 secY; preprotein translocase subunit SecY D ShL2_00246 secY_1; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D ShL2_01165 yajC; Sec family Type I general secretory pathway preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC D ShL2_00249 secA2; Sec family Type I general secretory pathway protein SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D ShL2_01991 secA; Sec family Type I general secretory pathway preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D ShL2_01611 ftsY; cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor D ShL2_01609 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] C 05111 Biofilm formation - Vibrio cholerae C 02025 Biofilm formation - Pseudomonas aeruginosa C 02026 Biofilm formation - Escherichia coli B B 09142 Cell motility C 02030 Bacterial chemotaxis D ShL2_00105 rbsR_1; sugar-binding transcriptional regulator, LacI K10439 rbsB; ribose transport system substrate-binding protein C 02040 Flagellar assembly [PATH:shh02040] D ShL2_00538 amino acid ABC superfamily ATP binding cassette transporter, binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D ShL2_01237 rpoD; RNA polymerase sigma-70 factor RpoD K03086 rpoD; RNA polymerase primary sigma factor C 04814 Motor proteins C 04820 Cytoskeleton in muscle cells D ShL2_01962 eno; enolase (2-phosphoglycerate dehydrogenase) K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 04810 Regulation of actin cytoskeleton # A09150 Organismal Systems B B 09151 Immune system C 04640 Hematopoietic cell lineage C 04610 Complement and coagulation cascades C 04611 Platelet activation C 04613 Neutrophil extracellular trap formation C 04620 Toll-like receptor signaling pathway C 04624 Toll and Imd signaling pathway C 04621 NOD-like receptor signaling pathway C 04622 RIG-I-like receptor signaling pathway C 04623 Cytosolic DNA-sensing pathway C 04625 C-type lectin receptor signaling pathway C 04650 Natural killer cell mediated cytotoxicity C 04612 Antigen processing and presentation C 04660 T cell receptor signaling pathway C 04658 Th1 and Th2 cell differentiation C 04659 Th17 cell differentiation C 04657 IL-17 signaling pathway C 04662 B cell receptor signaling pathway C 04664 Fc epsilon RI signaling pathway C 04666 Fc gamma R-mediated phagocytosis C 04670 Leukocyte transendothelial migration C 04672 Intestinal immune network for IgA production C 04062 Chemokine signaling pathway B B 09152 Endocrine system C 04911 Insulin secretion C 04910 Insulin signaling pathway C 04922 Glucagon signaling pathway C 04923 Regulation of lipolysis in adipocytes C 04920 Adipocytokine signaling pathway C 03320 PPAR signaling pathway C 04929 GnRH secretion C 04912 GnRH signaling pathway C 04913 Ovarian steroidogenesis C 04915 Estrogen signaling pathway C 04914 Progesterone-mediated oocyte maturation C 04917 Prolactin signaling pathway C 04921 Oxytocin signaling pathway C 04926 Relaxin signaling pathway C 04935 Growth hormone synthesis, secretion and action C 04918 Thyroid hormone synthesis C 04919 Thyroid hormone signaling pathway C 04928 Parathyroid hormone synthesis, secretion and action C 04916 Melanogenesis C 04924 Renin secretion C 04614 Renin-angiotensin system C 04925 Aldosterone synthesis and secretion C 04927 Cortisol synthesis and secretion B B 09153 Circulatory system C 04260 Cardiac muscle contraction C 04261 Adrenergic signaling in cardiomyocytes C 04270 Vascular smooth muscle contraction B B 09154 Digestive system C 04970 Salivary secretion C 04971 Gastric acid secretion C 04972 Pancreatic secretion C 04976 Bile secretion C 04973 Carbohydrate digestion and absorption C 04974 Protein digestion and absorption C 04975 Fat digestion and absorption C 04979 Cholesterol metabolism C 04977 Vitamin digestion and absorption C 04980 Cobalamin transport and metabolism C 04978 Mineral absorption B B 09155 Excretory system C 04962 Vasopressin-regulated water reabsorption C 04960 Aldosterone-regulated sodium reabsorption C 04961 Endocrine and other factor-regulated calcium reabsorption C 04964 Proximal tubule bicarbonate reclamation C 04966 Collecting duct acid secretion B B 09156 Nervous system C 04724 Glutamatergic synapse C 04727 GABAergic synapse C 04725 Cholinergic synapse C 04728 Dopaminergic synapse C 04726 Serotonergic synapse C 04720 Long-term potentiation C 04730 Long-term depression C 04723 Retrograde endocannabinoid signaling C 04721 Synaptic vesicle cycle C 04722 Neurotrophin signaling pathway B B 09157 Sensory system C 04744 Phototransduction C 04745 Phototransduction - fly C 04740 Olfactory transduction C 04742 Taste transduction C 04750 Inflammatory mediator regulation of TRP channels B B 09158 Development and regeneration C 04320 Dorso-ventral axis formation C 04360 Axon guidance C 04361 Axon regeneration C 04380 Osteoclast differentiation B B 09149 Aging C 04211 Longevity regulating pathway C 04212 Longevity regulating pathway - worm C 04213 Longevity regulating pathway - multiple species B B 09159 Environmental adaptation C 04710 Circadian rhythm C 04713 Circadian entrainment C 04711 Circadian rhythm - fly C 04712 Circadian rhythm - plant C 04714 Thermogenesis C 04626 Plant-pathogen interaction # A09160 Human Diseases B B 09161 Cancer: overview C 05200 Pathways in cancer C 05202 Transcriptional misregulation in cancer C 05206 MicroRNAs in cancer C 05205 Proteoglycans in cancer C 05204 Chemical carcinogenesis - DNA adducts C 05207 Chemical carcinogenesis - receptor activation C 05208 Chemical carcinogenesis - reactive oxygen species C 05203 Viral carcinogenesis C 05230 Central carbon metabolism in cancer C 05231 Choline metabolism in cancer C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer B B 09162 Cancer: specific types C 05210 Colorectal cancer C 05212 Pancreatic cancer C 05225 Hepatocellular carcinoma C 05226 Gastric cancer C 05214 Glioma C 05216 Thyroid cancer C 05221 Acute myeloid leukemia C 05220 Chronic myeloid leukemia C 05217 Basal cell carcinoma C 05218 Melanoma C 05211 Renal cell carcinoma C 05219 Bladder cancer C 05215 Prostate cancer C 05213 Endometrial cancer C 05224 Breast cancer C 05222 Small cell lung cancer C 05223 Non-small cell lung cancer B B 09172 Infectious disease: viral C 05166 Human T-cell leukemia virus 1 infection C 05170 Human immunodeficiency virus 1 infection C 05161 Hepatitis B C 05160 Hepatitis C C 05171 Coronavirus disease - COVID-19 C 05164 Influenza A C 05162 Measles C 05168 Herpes simplex virus 1 infection C 05163 Human cytomegalovirus infection C 05167 Kaposi sarcoma-associated herpesvirus infection C 05169 Epstein-Barr virus infection C 05165 Human papillomavirus infection B B 09171 Infectious disease: bacterial C 05110 Vibrio cholerae infection C 05120 Epithelial cell signaling in Helicobacter pylori infection C 05130 Pathogenic Escherichia coli infection C 05132 Salmonella infection C 05131 Shigellosis C 05135 Yersinia infection C 05133 Pertussis C 05134 Legionellosis C 05150 Staphylococcus aureus infection C 05152 Tuberculosis C 05100 Bacterial invasion of epithelial cells B B 09174 Infectious disease: parasitic C 05146 Amoebiasis C 05144 Malaria C 05145 Toxoplasmosis C 05140 Leishmaniasis C 05142 Chagas disease C 05143 African trypanosomiasis B B 09163 Immune disease C 05310 Asthma C 05322 Systemic lupus erythematosus C 05323 Rheumatoid arthritis C 05320 Autoimmune thyroid disease C 05321 Inflammatory bowel disease C 05330 Allograft rejection C 05332 Graft-versus-host disease C 05340 Primary immunodeficiency B B 09164 Neurodegenerative disease C 05010 Alzheimer disease C 05012 Parkinson disease C 05014 Amyotrophic lateral sclerosis C 05016 Huntington disease C 05017 Spinocerebellar ataxia C 05020 Prion disease C 05022 Pathways of neurodegeneration - multiple diseases B B 09165 Substance dependence C 05030 Cocaine addiction C 05031 Amphetamine addiction C 05032 Morphine addiction C 05033 Nicotine addiction C 05034 Alcoholism B B 09166 Cardiovascular disease C 05417 Lipid and atherosclerosis C 05418 Fluid shear stress and atherosclerosis C 05410 Hypertrophic cardiomyopathy C 05412 Arrhythmogenic right ventricular cardiomyopathy C 05414 Dilated cardiomyopathy C 05415 Diabetic cardiomyopathy C 05416 Viral myocarditis B B 09167 Endocrine and metabolic disease C 04930 Type II diabetes mellitus C 04940 Type I diabetes mellitus C 04950 Maturity onset diabetes of the young C 04936 Alcoholic liver disease C 04932 Non-alcoholic fatty liver disease C 04931 Insulin resistance C 04933 AGE-RAGE signaling pathway in diabetic complications C 04934 Cushing syndrome B B 09175 Drug resistance: antimicrobial C 01501 beta-Lactam resistance [PATH:shh01501] D ShL2_01829 opp3A; oligopeptide ABC superfamily ATP binding cassette transporter, binding protein, Opp3A K15580 oppA; oligopeptide transport system substrate-binding protein D ShL2_01833 oppB; oligopeptide ABC superfamily ATP binding cassette transporter, membrane protein K15581 oppB; oligopeptide transport system permease protein D ShL2_01832 oppC; oligopeptide ABC superfamily ATP binding cassette transporter, membrane protein K15582 oppC; oligopeptide transport system permease protein D ShL2_01831 oppD; oligopeptide ABC superfamily ATP binding cassette transporter, ABC protein K15583 oppD; oligopeptide transport system ATP-binding protein D ShL2_01830 oppF; oligopeptide ABC superfamily ATP binding cassette transporter, ABC protein K10823 oppF; oligopeptide transport system ATP-binding protein D ShL2_02381 blaR1; beta-lactamase regulatory protein K02172 blaR1; bla regulator protein blaR1 D ShL2_02382 transcriptional repressor K02171 blaI; BlaI family transcriptional regulator, penicillinase repressor D ShL2_02380 blaZ; beta-lactamase precursor, BlaZ K18766 blaZ; beta-lactamase class A BlaZ [EC:3.5.2.6] D ShL2_00029 mecA; penicillin-binding protein 2 prime K02545 mecA; penicillin-binding protein 2 prime [EC:3.4.16.4] D ShL2_02102 abcA; ABC superfamily ATP binding cassette transporter, ABC protein K18104 abcA; ATP-binding cassette, subfamily B, bacterial AbcA/BmrA [EC:7.6.2.2] D ShL2_01667 pbpA; penicillin-binding protein 1 K12552 pbpA; penicillin-binding protein 1 [EC:3.4.-.-] D ShL2_01247 pbp3; penicillin-binding protein 3 K12553 pbp3; penicillin-binding protein 3 [EC:3.4.-.-] D ShL2_01345 pbp2; glycosyl transferase family protein K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] C 01502 Vancomycin resistance [PATH:shh01502] D ShL2_00844 ddl; D-alanyl-alanine synthetase A K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D ShL2_01392 alr2; alanine racemase family protein K01775 alr; alanine racemase [EC:5.1.1.1] D ShL2_00851 alr; alanine racemase 1 K01775 alr; alanine racemase [EC:5.1.1.1] D ShL2_00845 murF; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D ShL2_01666 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D ShL2_01372 murG; N-acetylglucosaminyl transferase, MurG K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D ShL2_00111 vanY; D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:shh01503] D ShL2_01171 lytH; N-acetylmuramoyl-L-alanine amidase family protein K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D ShL2_01083 Trypsin-like serine endoprotease K04771 degP; serine protease Do [EC:3.4.21.107] D ShL2_02083 graS; sensor histidine kinase, GraS K19077 graS; two-component system, OmpR family, sensor histidine kinase GraS [EC:2.7.13.3] D ShL2_02084 graR; winged helix family two component transcriptional regulator K19078 graR; two-component system, OmpR family, response regulator protein GraR D ShL2_01880 dltB; D-alanine membrane transfer protein K03739 dltB; membrane protein involved in D-alanine export D ShL2_01879 dltC; D-alanine-activating enzyme/D-alanine-D-alanyl, dltC protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D ShL2_01878 dltD; D-alanine lipoteichoic acid and wall teichoic acid esterification secreted protein K03740 dltD; D-alanine transfer protein D ShL2_01426 fmtC; oxacillin resistance-related FmtC protein K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3] D ShL2_02082 antimicrobial peptide ABC transporter ATPase K19079 vraF; cationic antimicrobial peptide transport system ATP-binding protein D ShL2_02081 permease K19080 vraG; cationic antimicrobial peptide transport system permease protein B B 09176 Drug resistance: antineoplastic C 01521 EGFR tyrosine kinase inhibitor resistance C 01524 Platinum drug resistance C 01523 Antifolate resistance C 01522 Endocrine resistance # A09180 Brite Hierarchies B B 09181 Protein families: metabolism C 01000 Enzymes [BR:shh01000] C 01001 Protein kinases [BR:shh01001] D ShL2_01627 pknB; non-specific serine/threonine protein kinase K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1] D ShL2_00856 rsbW; anti-sigma-B factor, serine-protein kinase K04757 rsbW; serine/threonine-protein kinase RsbW [EC:2.7.11.1] D ShL2_00294 cap5B; capsular polysaccharide biosynthesis protein Cap5B K00903 epsB; protein-tyrosine kinase [EC:2.7.10.3] D ShL2_01118 phoR; alkaline phosphatase synthesis sensor protein PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D ShL2_01310 srrB_2; integral membrane sensor signal transduction histidine kinase K07651 resE; two-component system, OmpR family, sensor histidine kinase ResE [EC:2.7.13.3] D ShL2_00018 walK; multi-sensor signal transduction histidine kinase, WalK K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3] D ShL2_02083 graS; sensor histidine kinase, GraS K19077 graS; two-component system, OmpR family, sensor histidine kinase GraS [EC:2.7.13.3] D ShL2_00313 integral membrane sensor signal transduction histidine kinase K19081 braS; two-component system, OmpR family, sensor histidine kinase BraS/BceS [EC:2.7.13.3] D ShL2_01375 arlS; signal transduction histidine kinase K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3] D ShL2_00595 hssS; integral membrane sensor signal transduction histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3] D ShL2_01464 sensor histidine kinase K07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3] D ShL2_00957 vraS; integral membrane sensor signal transduction histidine kinase K07681 vraS; two-component system, NarL family, vancomycin resistance sensor histidine kinase VraS [EC:2.7.13.3] D ShL2_00559 nreB; oxygen sensor histidine kinase nreB K07683 nreB; two-component system, NarL family, sensor histidine kinase NreB [EC:2.7.13.3] D ShL2_00997 yhcS; two-component response regulator sensor protein,histidine kinase K02480 K02480; two-component system, NarL family, sensor kinase [EC:2.7.13.3] D ShL2_00883 accessory gene regulator protein C K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] C 01009 Protein phosphatases and associated proteins [BR:shh01009] D ShL2_01111 pfkA; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D ShL2_01628 protein phosphatase 2C domain-containing protein K20074 prpC; PPM family protein phosphatase [EC:3.1.3.16] C 01002 Peptidases and inhibitors [BR:shh01002] D ShL2_01650 lspA; lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] D ShL2_00211 pcp; C15 family pyroglutamyl-peptidase I K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3] D ShL2_02357 guaA; bifunctional GMP synthase/glutamine amidotransferase protein K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D ShL2_00329 secretory antigen K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] D ShL2_01756 purF; amidophosphoribosyltransferase precursor K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D ShL2_02325 gltB; glutamate synthase (NADPH), large subunit K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] D ShL2_00773 glmS; glucosamine--fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D ShL2_00968 pfpI; intracellular protease K05520 yhbO; deglycase [EC:3.5.1.124] D ShL2_00215 penicillin V acylase K24041 yxeI; penicillin V amidase [EC:3.5.1.11] D ShL2_00438 srtA; sortase A transpeptidase K07284 srtA; sortase A [EC:3.4.22.70] D ShL2_00885 agrB; accessory gene regulator B K07813 agrB; accessory gene regulator B D ShL2_01795 hypothetical protein K07052 K07052; CAAX protease family protein D ShL2_00202 CAAX amino terminal protease self-immunity K07052 K07052; CAAX protease family protein D ShL2_00204 metal-dependent membrane protease K07052 K07052; CAAX protease family protein D ShL2_00205 metal-dependent membrane protease K07052 K07052; CAAX protease family protein D ShL2_00167 CAAX amino terminal protease self-immunity K07052 K07052; CAAX protease family protein D ShL2_00889 metal-dependent membrane protease K07052 K07052; CAAX protease family protein D ShL2_00494 CAAX amino terminal protease self-immunity K07052 K07052; CAAX protease family protein D ShL2_01819 oligoendopeptidase F K08602 pepF; oligoendopeptidase F [EC:3.4.24.-] D ShL2_00111 vanY; D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D ShL2_01870 ampA; cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] D ShL2_00059 argE_1; succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D ShL2_01057 Peptidase family M20/M25/M40 K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D ShL2_02115 argE_3; succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D ShL2_01288 M20/M25/M40 family peptidase K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4] D ShL2_02001 pepT; M20 family peptidase T K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4] D ShL2_00385 M23/M37 peptidase domain-containing protein K21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-] D ShL2_00951 M24 family methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D ShL2_01102 hypothetical protein K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9] D ShL2_01270 M24B family Xaa-Pro dipeptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] D ShL2_00963 ampS; peptidase M29, aminopeptidase II K19689 ampS; aminopeptidase [EC:3.4.11.-] D ShL2_02285 ftsH; cell-division protein (ATP-dependent Zn metallopeptidase) K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D ShL2_01064 pepA1; M42 family glutamyl aminopeptidase K01261 pepA; glutamyl aminopeptidase [EC:3.4.11.7] D ShL2_01420 M42 glutamyl aminopeptidase K01269 yhfE; aminopeptidase [EC:3.4.11.-] D ShL2_01585 membrane-associated zinc metalloprotease K11749 rseP; regulator of sigma E protease [EC:3.4.24.-] D ShL2_02381 blaR1; beta-lactamase regulatory protein K02172 blaR1; bla regulator protein blaR1 D ShL2_00097 splF; Serine protease SplF precursor K01318 sspA; glutamyl endopeptidase [EC:3.4.21.19] D ShL2_01083 Trypsin-like serine endoprotease K04771 degP; serine protease Do [EC:3.4.21.107] D ShL2_00221 pbp4_1; serine-type D-Ala-D-Ala carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D ShL2_02104 pbp4_2; serine-type D-Ala-D-Ala carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D ShL2_01974 clpP; ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] D ShL2_01445 lexA; DNA damage-inducible repressor K01356 lexA; repressor LexA [EC:3.4.21.88] D ShL2_02443 Sec family Type I general secretory pathway S26 family signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D ShL2_01847 Sec family Type I general secretory pathway S26 family signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D ShL2_01848 lepB; Sec family Type I general secretory pathway S26 family signal peptidase I, LepB K03100 lepB; signal peptidase I [EC:3.4.21.89] D ShL2_01370 serine protease K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] D ShL2_01250 gluP; peptidase, rhomboid family protein K19225 gluP; rhomboid protease GluP [EC:3.4.21.105] D ShL2_01594 clpQ; T01 family HslV component of HsIUV peptidase K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2] D ShL2_00431 ggt; gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D ShL2_01189 peptidase U32 family protein K08303 prtC; U32 family peptidase [EC:3.4.-.-] D ShL2_01188 peptidase U32 family protein K08303 prtC; U32 family peptidase [EC:3.4.-.-] C 01003 Glycosyltransferases [BR:shh01003] D ShL2_01804 ypfP; UDP-glucose diacylglycerol glucosyltransferase K03429 ugtP; processive 1,2-diacylglycerol beta-glucosyltransferase [EC:2.4.1.315] D ShL2_01345 pbp2; glycosyl transferase family protein K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D ShL2_01079 mrcB; membrane carboxypeptidase K12551 sgtA; monofunctional glycosyltransferase [EC:2.4.99.28] D ShL2_00969 sgtB; monofunctional glycosyltransferase K04478 sgtB; monofunctional glycosyltransferase [EC:2.4.99.28] D ShL2_02110 wecG; teichoic acid biosynthesis protein K05946 tagA; N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase [EC:2.4.1.187] D ShL2_01997 glycosyl transferase family protein K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D ShL2_00067 glycosyl transferase family protein K22708 tarS; poly(ribitol-phosphate) beta-N-acetylglucosaminyltransferase [EC:2.4.1.355] D ShL2_02038 undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase K25617 csbB; lipoteichoic acid polyisoprenyl-phosphate beta-N-acetylglucosaminyltransferase [EC:2.4.-.-] D ShL2_01604 yfhO; membrane protein YfhO K25619 yfhO; lipoteichoic acid glycosylation protein C 01005 Lipopolysaccharide biosynthesis proteins [BR:shh01005] D ShL2_01997 glycosyl transferase family protein K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D ShL2_00304 cap5M; capsular polysaccharide biosynthesis galactosyltransferase Cap5M K13012 wbqP; O-antigen biosynthesis protein WbqP C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:shh01011] D ShL2_00802 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D ShL2_00826 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D ShL2_02006 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D ShL2_01069 murC; UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D ShL2_01665 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D ShL2_01803 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase K05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7] D ShL2_00844 ddl; D-alanyl-alanine synthetase A K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D ShL2_00689 fmhB; peptidoglycan pentaglycine interpeptide biosynthetic protein FmhB K11693 femX; peptidoglycan pentaglycine glycine transferase (the first glycine) [EC:2.3.2.16] D ShL2_01411 femA; glycine interpeptide bridge formation protein FemA K11694 femA; peptidoglycan pentaglycine glycine transferase (the second and third glycine) [EC:2.3.2.17] D ShL2_01410 femB; glycine interpeptide bridge formation protein FemB K11695 femB; peptidoglycan pentaglycine glycine transferase (the fourth and fifth glycine) [EC:2.3.2.18] D ShL2_01599 fmhA_2; FemAB family peptidoglycan biosynthesis protein K12554 murN; alanine adding enzyme [EC:2.3.2.-] D ShL2_01392 alr2; alanine racemase family protein K01775 alr; alanine racemase [EC:5.1.1.1] D ShL2_00851 alr; alanine racemase 1 K01775 alr; alanine racemase [EC:5.1.1.1] D ShL2_01681 murI; glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3] D ShL2_01666 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D ShL2_01372 murG; N-acetylglucosaminyl transferase, MurG K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D ShL2_02058 bacA; bacitracin resistance protein, undecaprenyl pyrophosphate phosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D ShL2_01373 phosphoesterase, PA-phosphatase-like protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] D ShL2_01345 pbp2; glycosyl transferase family protein K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D ShL2_00029 mecA; penicillin-binding protein 2 prime K02545 mecA; penicillin-binding protein 2 prime [EC:3.4.16.4] D ShL2_01667 pbpA; penicillin-binding protein 1 K12552 pbpA; penicillin-binding protein 1 [EC:3.4.-.-] D ShL2_01247 pbp3; penicillin-binding protein 3 K12553 pbp3; penicillin-binding protein 3 [EC:3.4.-.-] D ShL2_00221 pbp4_1; serine-type D-Ala-D-Ala carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D ShL2_02104 pbp4_2; serine-type D-Ala-D-Ala carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D ShL2_01079 mrcB; membrane carboxypeptidase K12551 sgtA; monofunctional glycosyltransferase [EC:2.4.99.28] D ShL2_00969 sgtB; monofunctional glycosyltransferase K04478 sgtB; monofunctional glycosyltransferase [EC:2.4.99.28] D ShL2_00111 vanY; D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D ShL2_00329 secretory antigen K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] D ShL2_00385 M23/M37 peptidase domain-containing protein K21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-] D ShL2_00438 srtA; sortase A transpeptidase K07284 srtA; sortase A [EC:3.4.22.70] D ShL2_01171 lytH; N-acetylmuramoyl-L-alanine amidase family protein K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] C 01004 Lipid biosynthesis proteins [BR:shh01004] D ShL2_01616 fabD; malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D ShL2_01836 fabH; 3-oxoacyl synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D ShL2_01835 fabB; 3-oxoacyl-(acyl carrier protein) synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D ShL2_01567 3-oxoacyl-acyl carrier protein reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D ShL2_01615 fabG_3; 3-oxoacyl-ACP reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D ShL2_00827 fabZ; (3R)-hydroxymyristoyl-ACP dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D ShL2_02408 fabI_2; enoyl-acyl-carrier-protein reductase, FabI K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] D ShL2_01809 fabI_1; enoyl-acyl-carrier-protein reductase, FabI K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] D ShL2_01077 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D ShL2_00342 acsA2; AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D ShL2_02213 vraA; long chain fatty acid CoA ligase, VraA K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D ShL2_01617 plsX; glycerol-3-phosphate acyltransferase PlsX K03621 plsX; phosphate acyltransferase [EC:2.3.1.274] D ShL2_01432 plsY; Glycerol-3-phosphate acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D ShL2_01084 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] C 01008 Polyketide biosynthesis proteins C 01006 Prenyltransferases [BR:shh01006] D ShL2_01278 ispA; geranyltranstransferase K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29] D ShL2_01325 heptaprenyl diphosphate synthase subunit 1 K00805 hepS; heptaprenyl diphosphate synthase component 1 [EC:2.5.1.30] D ShL2_01327 gerCC; iron (Fe3+) ABC superfamily ATP binding cassettetransporter, membrane protein K24873 hepT; heptaprenyl diphosphate synthase component 2 [EC:2.5.1.30] D ShL2_01587 uppS; di-trans, poly-cis-decaprenylcistransferase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D ShL2_00391 squalene/phytoene synthase K10208 crtM; 4,4'-diapophytoene synthase [EC:2.5.1.96] D ShL2_01540 miaA; tRNA delta 2-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] D ShL2_01784 menA; DHNA-octaprenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74] D ShL2_01706 ctaB; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] C 01007 Amino acid related enzymes [BR:shh01007] D ShL2_02267 gltX; glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24] D ShL2_01080 tyrS; tyrosyl-tRNA synthetase, TyrS K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D ShL2_01823 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D ShL2_02265 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D ShL2_02142 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D ShL2_02306 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D ShL2_01654 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D ShL2_01146 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D ShL2_01047 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D ShL2_02279 lysS; asparaginyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D ShL2_01173 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D ShL2_01341 asnC; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D ShL2_01172 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D ShL2_01233 glyS; glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D ShL2_00008 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D ShL2_01584 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D ShL2_00061 thrS_1; threonyl-tRNA synthetase 1 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D ShL2_01127 thrS_2; threonyl-tRNA synthetase 1 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D ShL2_01183 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D ShL2_01693 pheS; phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D ShL2_01692 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D ShL2_00393 N-succinyldiaminopimelate aminotransferase K08969 mtnE; L-glutamine---4-(methylsulfanyl)-2-oxobutanoate aminotransferase [EC:2.6.1.117] D ShL2_01779 aromatic amino acid transferase K00841 patA; aminotransferase [EC:2.6.1.-] D ShL2_02020 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D ShL2_02242 kbl; pyridoxal phosphate-dependent acyltransferase K00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29] D ShL2_00144 aromatic amino acid transferase K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D ShL2_01855 rocD; ornithine--oxo-acid transaminase K00819 rocD; ornithine--oxo-acid transaminase [EC:2.6.1.13] D ShL2_00362 4-aminobutyrate aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D ShL2_00983 gsaB; glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D ShL2_01143 hemL; glutamate-1-semialdehyde aminotransferase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D ShL2_01058 dat; D-alanine aminotransferase K00824 dat; D-alanine transaminase [EC:2.6.1.21] D ShL2_02236 ilvE; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] C 00199 Cytochrome P450 C 00194 Photosynthesis proteins [BR:shh00194] D ShL2_00824 atpE; ATP synthase epsilon chain, AtpE K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D ShL2_00823 atpB_2; ATP synthase subunit beta, AtpB K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D ShL2_00822 atpG; ATP synthase subunit gamma, AtpG K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D ShL2_00821 atpA_2; ATP synthase subunit alpha, AtpA K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D ShL2_00820 atpD; ATP synthase subunit delta K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D ShL2_00819 atpB_1; ATP synthase subunit beta, AtpB_1 K02109 ATPF0B; F-type H+-transporting ATPase subunit b D ShL2_00818 atpC; ATP synthase subunit C, AtpC K02110 ATPF0C; F-type H+-transporting ATPase subunit c D ShL2_00817 atpA_1; ATP synthase subunit alpha, AtpA_1 K02108 ATPF0A; F-type H+-transporting ATPase subunit a D ShL2_00816 atpI; ATP synthase I, AtpI K02116 atpI; ATP synthase protein I B B 09182 Protein families: genetic information processing C 03000 Transcription factors [BR:shh03000] D ShL2_00525 transcriptional activator K13653 K13653; AraC family transcriptional regulator D ShL2_02326 gltC_2; transcriptional activator of glutamate synthase operon K09681 gltC; LysR family transcriptional regulator, transcription activator of glutamate synthase operon D ShL2_00268 LysR family transcriptional regulator K21900 cysL; LysR family transcriptional regulator, transcriptional activator of the cysJI operon D ShL2_00735 deoR; deoR-family regulatory protein K02530 lacR; DeoR family transcriptional regulator, lactose phosphotransferase system repressor D ShL2_02044 fructose operon transcriptional repressor K03436 fruR2; DeoR family transcriptional regulator, fructose operon transcriptional repressor D ShL2_01234 ccpN; Transcriptional repressor CcpN K23774 ccpN; DeoR family transcriptional regulator, catabolite repression regulator D ShL2_00100 ccpA_1; global transcriptional regulator, catabolite control protein A K02529 galR; LacI family transcriptional regulator, galactose operon repressor D ShL2_01074 ccpA_2; global transcriptional regulator, catabolite control protein A K02529 galR; LacI family transcriptional regulator, galactose operon repressor D ShL2_00879 scrR; sucrose operon repressor K03484 scrR; LacI family transcriptional regulator, sucrose operon repressor D ShL2_02321 treR; trehalose operon transcription repressor treR K03486 treR2; GntR family transcriptional regulator, trehalose operon transcriptional repressor D ShL2_00349 UbiC transcription regulator-associated domain protein K03489 yydK; GntR family transcriptional regulator, transcriptional regulator of bglA D ShL2_01570 UTRA domain transcriptional regulator K03710 K03710; GntR family transcriptional regulator D ShL2_02277 GntR family transcriptional regulator K00375 K00375; GntR family transcriptional regulator / MocR family aminotransferase D ShL2_00468 gntR; gluconate operon transcriptional repressor K11476 gntR; GntR family transcriptional regulator, gluconate operon transcriptional repressor D ShL2_02155 betI; HTH-type transcriptional regulator BetI K02167 betI; TetR/AcrR family transcriptional regulator, transcriptional repressor of bet genes D ShL2_02387 qacR; transcriptional regulator QacR K18938 qacR; TetR/AcrR family transcriptional regulator, repressor for qacA D ShL2_00448 MarR family transcriptional regulatory protein K15973 mhqR; MarR family transcriptional regulator, 2-MHQ and catechol-resistance regulon repressor D ShL2_02055 MarR family transcriptional regulator K18906 mgrA; MarR family transcriptional regulator, multiple gene regulator MgrA D ShL2_00575 mepR; mepA/mepB repressor and autoregulator K18909 mepR; MarR family transcriptional regulator, repressor for mepA D ShL2_01043 rot; repressor of toxins, Rot K20338 rot; MarR family transcriptional regulator, global regulator for virulence D ShL2_00601 tcaR; teicoplanin resistance operon transcriptional regulator TcaR K21454 tcaR; MarR family transcriptional regulator, teicoplanin-associated locus regulator D ShL2_00140 transcriptional regulator K23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator D ShL2_00563 transcriptional regulator K23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator D ShL2_01535 glnR; MerR family transcriptional regulator K03713 glnR; MerR family transcriptional regulator, glutamine synthetase repressor D ShL2_00083 MerR family transcriptional regulator K21745 adhR; MerR family transcriptional regulator, aldehyde-responsive regulator D ShL2_01303 fur; Ferric uptake regulation protein Fur K03711 fur; Fur family transcriptional regulator, ferric uptake regulator D ShL2_01244 zinc-specific metalloregulatory protein K02076 zurR; Fur family transcriptional regulator, zinc uptake regulator D ShL2_00986 perR; transcriptional regulator Fur family protein K09825 perR; Fur family transcriptional regulator, peroxide stress response regulator D ShL2_00282 Crp family transcriptional regulator K21828 arcR; CRP/FNR family transcriptional regulator, arginine deiminase pathway regulator D ShL2_01176 Rfr2 family transcriptional regulator K17472 cymR; Rrf2 family transcriptional regulator, cysteine metabolism repressor D ShL2_00027 arsR; arsenical resistance operon repressor K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor D ShL2_02182 cadX_3; cadmium efflux system accessory protein K21903 cadC; ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor D ShL2_00024 cadX_1; cadmium efflux system accessory protein K21903 cadC; ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor D ShL2_00045 cadX_2; cadmium efflux system accessory protein K21903 cadC; ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor D ShL2_00780 transcriptional repressor, arsR family K22043 czrA; ArsR family transcriptional regulator, zinc-responsive transcriptional repressor D ShL2_00151 Transcriptional regulator PadR-like family protein K10947 K10947; PadR family transcriptional regulator D ShL2_02113 iron-dependent repressor K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator D ShL2_00631 phosphosugar-binding transcriptional regulator K03481 glvR; RpiR family transcriptional regulator, glv operon transcriptional regulator D ShL2_02382 transcriptional repressor K02171 blaI; BlaI family transcriptional regulator, penicillinase repressor D ShL2_01339 birA; bifunctional biotin-(acetyl-CoA carboxylase) ligase / biotin operon repressor K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] D ShL2_00333 transcriptional regulator-like protein K22109 gbsR; HTH-type transcriptional regulator, glycine betaine synthesis regulator D ShL2_02300 purR; pur operon repressor K09685 purR; HTH-type transcriptional regulator, purine operon repressor D ShL2_00875 rex; redox-sensing transcriptional repressor rex K01926 rex; redox-sensing transcriptional repressor D ShL2_01592 codY; GTP-sensing transcriptional pleiotropic repressor CodY K03706 codY; transcriptional pleiotropic repressor D ShL2_00615 transcriptional regulator K07729 K07729; putative transcriptional regulator D ShL2_02174 transcriptional regulator K07729 K07729; putative transcriptional regulator D ShL2_00229 transcriptional regulator K07729 K07729; putative transcriptional regulator D ShL2_00177 transcriptional regulator K07729 K07729; putative transcriptional regulator D ShL2_00852 mazE; Antitoxin MazE K07723 ndoAI; CopG family transcriptional regulator / antitoxin EndoAI D ShL2_01428 glcT; transcriptional antiterminator K03480 glcT; transcriptional antiterminator D ShL2_02405 csoR_2; Copper-sensing transcriptional repressor CsoR K21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor D ShL2_00839 csoR_1; Copper-sensing transcriptional repressor CsoR K21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor D ShL2_02430 parB; chromosome/plasmid partitioning protein ParB K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D ShL2_02453 noc; ParB family nucleoid occlusion protein, Noc K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D ShL2_01545 glpP; glycerol uptake operon antiterminator regulatory protein, GlpP K02443 glpP; glycerol uptake operon antiterminator D ShL2_01279 ahrC; arginine repressor K03402 argR; transcriptional regulator of arginine metabolism D ShL2_00279 argR; ArgR family transcriptional regulator K03402 argR; transcriptional regulator of arginine metabolism D ShL2_01216 hrcA; heat-inducible transcription repressor HrcA K03705 hrcA; heat-inducible transcriptional repressor D ShL2_00831 tenA; thiaminase-2 K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2] D ShL2_00460 tenI; Regulatory protein TenI K10810 tenI; thiazole tautomerase (transcriptional regulator TenI) [EC:5.3.99.10] D ShL2_02273 ctsR; class III stress genes transcriptional repressor K03708 ctsR; transcriptional regulator of stress and heat shock response D ShL2_01967 DeoR family transcriptional regulator K05311 cggR; central glycolytic genes regulator D ShL2_01648 pyrR; bifunctional protein pyrimidine operon regulatory protein/uracil phosphoribosyltransferase, PyrR K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9] D ShL2_01124 nrdR; transcriptional regulator NrdR K07738 nrdR; transcriptional repressor NrdR D ShL2_01789 comK; competence transcription factor ComK K02250 comK; competence protein ComK D ShL2_01670 mraZ; cell division protein MraZ K03925 mraZ; transcriptional regulator MraZ C 03021 Transcription machinery [BR:shh03021] D ShL2_00727 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D ShL2_02251 rpoB_1; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D ShL2_02250 rpoC; DNA-directed RNA polymerase beta' chain protein K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D ShL2_00798 rpoE; DNA-directed RNA polymerase subunit delta K03048 rpoE; DNA-directed RNA polymerase subunit delta D ShL2_01636 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D ShL2_01237 rpoD; RNA polymerase sigma-70 factor RpoD K03086 rpoD; RNA polymerase primary sigma factor D ShL2_00857 sigB; RNA polymerase sigma factor SigB K03090 sigB; RNA polymerase sigma-B factor D ShL2_02261 RNA polymerase factor sigma-70 K27000 sigH; RNA polymerase sigma-H factor D ShL2_01581 hypothetical protein K02600 nusA; transcription termination/antitermination protein NusA D ShL2_01275 nusB; N utilization substance protein B K03625 nusB; transcription antitermination protein NusB D ShL2_02259 hypothetical protein K02601 nusG; transcription termination/antitermination protein NusG D ShL2_00854 rsbU; sigma factor sigB regulation protein K07315 rsbU_P; phosphoserine phosphatase RsbU/P [EC:3.1.3.3] D ShL2_00855 rsbV; anti-sigma-B factor, antagonist K04749 rsbV; anti-sigma B factor antagonist D ShL2_00856 rsbW; anti-sigma-B factor, serine-protein kinase K04757 rsbW; serine/threonine-protein kinase RsbW [EC:2.7.11.1] D ShL2_01191 greA; transcription elongation factor GreA K03624 greA; transcription elongation factor GreA D ShL2_00805 rho; methicillin resistance expression factor K03628 rho; transcription termination factor Rho C 03019 Messenger RNA biogenesis [BR:shh03019] D ShL2_01613 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D ShL2_01734 mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) K12574 rnj; ribonuclease J [EC:3.1.-.-] D ShL2_01572 metallo-beta-lactamase family protein K12574 rnj; ribonuclease J [EC:3.1.-.-] D ShL2_01557 phosphodiesterase K18682 rny; ribonucrease Y [EC:3.1.-.-] D ShL2_01958 rnr; exoribonuclease, VacB/RNase II family K12573 rnr; ribonuclease R [EC:3.1.13.1] D ShL2_01004 yhaM; 3'-5' exoribonuclease YhaM K03698 cbf; 3'-5' exoribonuclease [EC:3.1.-.-] D ShL2_00846 ATP-dependent RNA helicase DEAD box family protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D ShL2_01240 ATP-dependent RNA helicase DEAD/DEAH box family protein K18692 cshB; ATP-dependent RNA helicase CshB [EC:5.6.2.7] D ShL2_01314 recQ; ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] D ShL2_02024 ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] D ShL2_01962 eno; enolase (2-phosphoglycerate dehydrogenase) K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D ShL2_01573 pnpA; polynucleotide phosphorylase/polyadenylase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D ShL2_00805 rho; methicillin resistance expression factor K03628 rho; transcription termination factor Rho D ShL2_01111 pfkA; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D ShL2_01218 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK D ShL2_00891 groEL; co-chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D ShL2_01539 hfq; RNA chaperone, host factor-1 protein K03666 hfq; host factor-I protein D ShL2_00485 ppk; Polyphosphate kinase K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] D ShL2_01978 P-loop ATPase/kinase K06958 rapZ; RNase adapter protein RapZ C 03041 Spliceosome C 03011 Ribosome [BR:shh03011] D ShL2_01320 rpsA; 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1 D ShL2_01591 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D ShL2_00707 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D ShL2_01091 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D ShL2_00718 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D ShL2_02424 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6 D ShL2_02247 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D ShL2_00715 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D ShL2_00733 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D ShL2_00700 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D ShL2_00726 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D ShL2_02248 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D ShL2_00725 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D ShL2_00714 rpsN_1; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D ShL2_01448 rpsN_2; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D ShL2_01574 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D ShL2_01608 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16 D ShL2_00710 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D ShL2_02422 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18 D ShL2_00705 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D ShL2_01213 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20 D ShL2_01223 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21 D ShL2_02257 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D ShL2_00704 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D ShL2_00701 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D ShL2_00702 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4 D ShL2_00713 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D ShL2_00716 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D ShL2_00014 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9 D ShL2_02255 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D ShL2_02258 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D ShL2_02254 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12 D ShL2_00732 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D ShL2_00711 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D ShL2_00720 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D ShL2_00708 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16 D ShL2_00728 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17 D ShL2_00717 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D ShL2_01605 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19 D ShL2_01131 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20 D ShL2_01156 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21 D ShL2_00706 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D ShL2_00703 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D ShL2_00712 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D ShL2_01158 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27 D ShL2_01623 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28 D ShL2_00709 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D ShL2_00719 rpmD; 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30 D ShL2_00806 rpmE2; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31 D ShL2_01695 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32 D ShL2_01449 rpmG_2; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D ShL2_01248 rpmG_1; 50S ribosomal protein L33 type 1 K02913 RP-L33; large subunit ribosomal protein L33 D ShL2_01130 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35 D ShL2_00724 rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36 D ShL2_02295 rplY; 50S ribosomal protein L25 Ctc-form K02897 RP-L25; large subunit ribosomal protein L25 D ShL2_02249 ribosomal protein L7Ae-like protein K07590 RP-L7A; large subunit ribosomal protein L7A D ShL2_r00003 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D ShL2_r00006 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D ShL2_r00013 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D ShL2_r00010 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D ShL2_r00009 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D ShL2_r00014 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D ShL2_r00001 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D ShL2_r00012 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D ShL2_r00016 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D ShL2_r00007 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D ShL2_r00004 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D ShL2_r00005 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D ShL2_r00011 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D ShL2_r00002 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D ShL2_r00008 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D ShL2_r00015 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA C 03009 Ribosome biogenesis [BR:shh03009] D ShL2_01613 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D ShL2_01231 era; GTP-binding protein Era K03595 era; GTPase D ShL2_01159 obgE; Spo0B-associated GTP-binding protein K03979 obgE; GTPase [EC:3.6.5.-] D ShL2_01581 hypothetical protein K02600 nusA; transcription termination/antitermination protein NusA D ShL2_01275 nusB; N utilization substance protein B K03625 nusB; transcription antitermination protein NusB D ShL2_02259 hypothetical protein K02601 nusG; transcription termination/antitermination protein NusG D ShL2_01055 rsuA; ribosomal small subunit pseudouridine synthase A K06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19] D ShL2_02303 ksgA; dimethyladenosine transferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D ShL2_01630 sun; ribosomal RNA small subunit methyltransferase B K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176] D ShL2_02253 methyltransferase small domain-containing protein K00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172] D ShL2_01699 site-specific DNA-methyltransferase (adenine-specific) K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171] D ShL2_01221 rsmE; 16S ribosomal RNA methyltransferase RsmE K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193] D ShL2_02454 gidB; glucose inhibited division protein B K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D ShL2_01669 mraW; S-adenosyl-methyltransferase MraW K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199] D ShL2_02307 tetrapyrrole (corrin/porphyrin) methylase K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198] D ShL2_02263 yacO; TrmH family RNA methyltransferase K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185] D ShL2_00022 rRNA large subunit methyltransferase K00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177] D ShL2_01746 SAM-dependent methyltransferase K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191] D ShL2_01629 rlmN; Ribosomal RNA large subunit methyltransferase N,Rlmn K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192] D ShL2_00942 RNA methyltransferase K03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190] D ShL2_01308 rluB; ribosomal large subunit pseudouridine synthase B, RluB K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22] D ShL2_01649 rluD; RluD subfamily ribosomal large subunit pseudouridine synthase K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D ShL2_01812 rluA1; RluD subfamily ribosomal large subunit pseudouridine synthase K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D ShL2_00996 rluA; RluA, Pseudouridylate synthase, 23S RNA-specific K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D ShL2_00872 rimI; ribosomal-protein-alanine acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266] D ShL2_02440 ribosomal-protein-serine N-acetyltransferase K03817 rimL; ribosomal-protein-serine acetyltransferase [EC:2.3.1.-] D ShL2_01607 rimM; 16S rRNA processing protein RimM K02860 rimM; 16S rRNA processing protein RimM D ShL2_01220 prmA; 50S ribosomal protein L11 methyltransferase K02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-] D ShL2_01185 Holliday junction resolvase K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-] D ShL2_02264 ribonuclease III K11145 mrnC; mini-ribonuclease III [EC:3.1.26.-] D ShL2_00846 ATP-dependent RNA helicase DEAD box family protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D ShL2_01240 ATP-dependent RNA helicase DEAD/DEAH box family protein K18692 cshB; ATP-dependent RNA helicase CshB [EC:5.6.2.7] D ShL2_01626 rsgA; ribosome small subunit-dependent GTPase A K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D ShL2_01321 engA; GTP-binding protein EngA K03977 engA; GTPase D ShL2_01603 rbgA; GTP-binding protein K14540 rbgA; ribosome biogenesis GTPase A D ShL2_01537 hflX; GTPase HflX K03665 hflX; GTPase D ShL2_01200 GTPase family protein K06948 yqeH; 30S ribosome assembly GTPase D ShL2_00810 sua5; yrdC/SUA5 multi-domain translation factor protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D ShL2_01169 relA; GTP pyrophosphokinase, (p)ppGpp synthetase I, RelA K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D ShL2_01577 rbfA; ribosome-binding factor A (P15B PROTEIN) K02834 rbfA; ribosome-binding factor A D ShL2_01582 rimP; Ribosome maturation factor RimP K09748 rimP; ribosome maturation factor RimP D ShL2_00003 ribosome-associated protein K14761 rlbA; ribosome-associated protein D ShL2_01205 rsfS; Ribosomal silencing factor RsfS K09710 ybeB; ribosome-associated protein D ShL2_01228 metalloprotease K07042 ybeY; probable rRNA maturation factor D ShL2_01202 yhbY; RNA-binding protein YbhY K07574 yhbY; RNA-binding protein D ShL2_01992 yfiA; sigma 54 modulation protein/ribosomal protein S30EA K05808 hpf; ribosome hibernation promoting factor D ShL2_02427 ychF; GTP-dependent nucleic acid-binding protein EngD K06942 ychF; ribosome-binding ATPase D ShL2_01696 hypothetical protein K07040 yceD; DUF177 domain-containing protein C 03016 Transfer RNA biogenesis [BR:shh03016] D ShL2_01294 metallo-beta-lactamase, AtsA/ElaC family K00784 rnz; ribonuclease Z [EC:3.1.26.11] D ShL2_01338 papS; polynucleotide adenylyltransferase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-] D ShL2_01584 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D ShL2_01654 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D ShL2_01047 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D ShL2_02306 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D ShL2_02142 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D ShL2_02279 lysS; asparaginyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D ShL2_01173 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D ShL2_01183 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D ShL2_01341 asnC; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D ShL2_01233 glyS; glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D ShL2_00061 thrS_1; threonyl-tRNA synthetase 1 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D ShL2_01127 thrS_2; threonyl-tRNA synthetase 1 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D ShL2_00008 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D ShL2_02265 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D ShL2_01146 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D ShL2_01172 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D ShL2_01693 pheS; phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D ShL2_01692 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D ShL2_01080 tyrS; tyrosyl-tRNA synthetase, TyrS K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D ShL2_01823 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D ShL2_01170 dtd; D-tyrosyl-tRNA (Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96] D ShL2_01009 hit; HIT family hydrolase K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D ShL2_01060 trmB; tRNA (guanine-N(7)-)-methyltransferase, TrmB K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33] D ShL2_00731 truA; tRNA pseudouridine synthase K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12] D ShL2_01576 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25] D ShL2_01094 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D ShL2_01179 nifS; cysteine desulfurase, NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D ShL2_00810 sua5; yrdC/SUA5 multi-domain translation factor protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D ShL2_01540 miaA; tRNA delta 2-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] D ShL2_02456 trmE; tRNA modification GTPase TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-] D ShL2_02455 gidA; glucose inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D ShL2_02267 gltX; glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24] D ShL2_02045 prolyl-tRNA synthetase K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-] D ShL2_02224 tRNA-specific adenosine deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33] D ShL2_01550 miaB; (dimethylallyl)adenosine tRNA methylthiotransferase K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3] D ShL2_01222 radical SAM domain-containing protein K18707 mtaB; threonylcarbamoyladenosine tRNA methylthiotransferase MtaB [EC:2.8.4.5] D ShL2_01596 gid; tRNA (uracil-5-)-methyltransferase Gid K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74] D ShL2_01606 trmD; tRNA (guanine-7-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D ShL2_01238 trmK; tRNA (adenine(22)-N(1))-methyltransferase K06967 trmK; tRNA (adenine22-N1)-methyltransferase [EC:2.1.1.217] D ShL2_00991 TrmH family RNA methyltransferase K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207] D ShL2_01694 spoU_trmH; SpoU rRNA methylase family protein K03437 spoU; RNA methyltransferase, TrmH family D ShL2_01180 trmU; tRNA (5-methyl aminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D ShL2_01872 sufA; iron-sulfur cluster assembly accessory protein K13628 iscA; iron-sulfur cluster assembly protein D ShL2_01163 queA; S-adenosylmethionine--tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17] D ShL2_02034 queC; queuosine biosynthesis protein QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D ShL2_00084 6-pyruvoyl tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D ShL2_02035 6-pyruvoyl-tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D ShL2_02036 queE; 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] D ShL2_02016 folE; NADPH-dependent 7-cyano-7-deazaguanine reductase K09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13] D ShL2_00990 phenylalanyl-tRNA synthetase subunit alpha K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6] D ShL2_00373 hypothetical protein K09765 queH; epoxyqueuosine reductase [EC:1.17.99.6] D ShL2_01164 tgt; queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29] D ShL2_01095 thiI; thiamine biosynthesis protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D ShL2_02287 tilS; tRNA(Ile)-lysidine synthetase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19] D ShL2_00871 glycoprotease K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB D ShL2_00873 DNA-binding/iron metalloprotein/AP endonuclease K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234] D ShL2_00870 yjeE; ATPase K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE D ShL2_01174 ThiF family protein K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase D ShL2_01697 hypothetical protein K27343 tmcAL; tRNA(Met) cytidine acetate ligase [EC:6.3.4.-] D ShL2_01958 rnr; exoribonuclease, VacB/RNase II family K12573 rnr; ribonuclease R [EC:3.1.13.1] D ShL2_01573 pnpA; polynucleotide phosphorylase/polyadenylase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] C 03012 Translation factors [BR:shh03012] D ShL2_01578 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2 D ShL2_01129 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3 D ShL2_00874 ABC transporter ATP-binding protein K06158 ABCF3; ATP-binding cassette, subfamily F, member 3 D ShL2_02437 ABC transporter ATP-binding protein K06158 ABCF3; ATP-binding cassette, subfamily F, member 3 D ShL2_01590 tsf; translation elongation factor Ts K02357 tsf; elongation factor Ts D ShL2_02245 tuf; translational elongation factor TU K02358 tuf; elongation factor Tu D ShL2_02246 fus; translational elongation factor G K02355 fusA; elongation factor G D ShL2_00808 prfA; peptide chain release factor RF1 K02835 prfA; peptide chain release factor 1 D ShL2_01588 frr; ribosome recycling factor K02838 frr; ribosome recycling factor D ShL2_00809 modification methylase HemK family protein K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297] D ShL2_02294 pth; peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29] D ShL2_00723 infA; translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1 D ShL2_01271 efp; translation elongation factor EF-P K02356 efp; elongation factor P D ShL2_01990 peptide chain release factor 2 K02836 prfB; peptide chain release factor 2 D ShL2_01801 peptide chain release factor 3 K02837 prfC; peptide chain release factor 3 C 03110 Chaperones and folding catalysts [BR:shh03110] D ShL2_01838 clpB; ATPase subunit of an ATP-dependent protease, ClpB K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB D ShL2_02270 Clp protease ATP binding subunit K03696 clpC; ATP-dependent Clp protease ATP-binding subunit ClpC D ShL2_01135 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX D ShL2_01593 hslU; ATP-dependent protease ATP-binding subunit K03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU D ShL2_01218 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK D ShL2_00891 groEL; co-chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D ShL2_01219 dnaJ; chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ D ShL2_02284 redox regulated Hsp33-like chaperonin K04083 hslO; molecular chaperone Hsp33 D ShL2_01217 grpE; heat shock molecular chaperone protein K03687 GRPE; molecular chaperone GrpE D ShL2_00562 small heat shock protein K13993 HSP20; HSP20 family protein D ShL2_00890 groES; co-chaperonin GroES K04078 groES; chaperonin GroES D ShL2_01083 Trypsin-like serine endoprotease K04771 degP; serine protease Do [EC:3.4.21.107] D ShL2_02285 ftsH; cell-division protein (ATP-dependent Zn metallopeptidase) K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D ShL2_00817 atpA_1; ATP synthase subunit alpha, AtpA_1 K02108 ATPF0A; F-type H+-transporting ATPase subunit a D ShL2_01858 ppi; cyclophilin type peptidyl-prolyl cis-trans isomerase K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] D ShL2_01005 prsA_1; peptidylprolyl isomerase, PrsA K07533 prsA; foldase protein PrsA [EC:5.2.1.8] D ShL2_01686 trxA; thioredoxin K03671 TXN; thioredoxin D ShL2_02406 glutaredoxin 3 K03676 grxC; glutaredoxin 3 C 04131 Membrane trafficking [BR:shh04131] D ShL2_01328 ndk; nucleoside diphosphate kinase superfamily protein K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D ShL2_00355 fdaB; fructose-bisphosphate aldolase K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D ShL2_01966 gap; glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D ShL2_00535 gpm; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D ShL2_02370 phosphoglycerate mutase family protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D ShL2_01112 pykA; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] C 04121 Ubiquitin system [BR:shh04121] C 03051 Proteasome C 03032 DNA replication proteins [BR:shh03032] D ShL2_01358 cell wall enzyme EbsB-like protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4] D ShL2_01323 histone family protein DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta D ShL2_00001 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein D ShL2_00015 dnaC; replicative DNA helicase DnaB K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D ShL2_01517 dnaI_2; primosomal protein K02315 dnaC; DNA replication protein DnaC D ShL2_01236 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D ShL2_01125 dnaB; chromosome replication initiation and membrane attachment protein K03346 dnaB; replication initiation and membrane attachment protein D ShL2_01126 dnaI_1; primosomal protein K11144 dnaI; primosomal protein DnaI D ShL2_00829 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D ShL2_02423 ssb; ssDNA-binding protein K03111 ssb; single-strand DNA-binding protein D ShL2_01522 ssDNA-binding protein K03111 ssb; single-strand DNA-binding protein D ShL2_01107 dnaE; DNA-directed DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D ShL2_01583 polC; DNA polymerase III subunit alpha K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D ShL2_00002 dnaN; DNA-directed DNA polymerase beta subunit, DnaN K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D ShL2_01211 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D ShL2_02312 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D ShL2_00945 Exonuclease, RNase T and DNA polymerase III K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D ShL2_02319 dnaX; DNA-directed DNA polymerase III subunit gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D ShL2_01602 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D ShL2_01691 rnhC; ribonuclease HIII K03471 rnhC; ribonuclease HIII [EC:3.1.26.4] D ShL2_01119 DNA-directed DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D ShL2_00935 lig; DNA ligase (polydeoxyribonucleotide syntase) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D ShL2_01353 exonuclease K23786 exoA; 5'-3' exonuclease [EC:3.1.11.-] D ShL2_00006 gyrA; DNA topoisomerase (ATP-hydrolyzing) subunit A, GyrA K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D ShL2_00005 gyrB_1; DNA topoisomerase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D ShL2_01430 parC; DNA topoisomerase (ATP-hydrolyzing) ParC K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D ShL2_01431 gyrB_2; DNA topoisomerase subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D ShL2_01597 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D ShL2_00697 topB; DNA topoisomerase K03169 topB; DNA topoisomerase III [EC:5.6.2.1] C 03036 Chromosome and associated proteins [BR:shh03036] D ShL2_01613 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D ShL2_00355 fdaB; fructose-bisphosphate aldolase K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D ShL2_01323 histone family protein DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta D ShL2_00001 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein D ShL2_00786 dps; non-heme iron-containing ferritin K04047 dps; starvation-inducible DNA-binding protein D ShL2_01539 hfq; RNA chaperone, host factor-1 protein K03666 hfq; host factor-I protein D ShL2_01612 smc; SMC superfamily ATP-binding chromosome segregation protein K03529 smc; chromosome segregation protein D ShL2_01306 scpA; chromosome segregation and condensation protein ScpA K05896 scpA; segregation and condensation protein A D ShL2_01307 scpB; transcriptional regulators (Ypuh-like) K06024 scpB; segregation and condensation protein B D ShL2_01663 ftsA; cell division protein K03590 ftsA; cell division protein FtsA D ShL2_02289 divIC; cell-division initiation protein K13052 divIC; cell division protein DivIC D ShL2_01571 ftsK; DNA translocase FtsK/SpoIIIE family protein K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family D ShL2_01668 ftsL; cell division and chromosome partitioning protein, FtsL K03586 ftsL; cell division protein FtsL D ShL2_01664 div1b; cell division protein K03589 ftsQ; cell division protein FtsQ D ShL2_01710 ftsW; cell division membrane protein K03588 ftsW; cell division protein FtsW D ShL2_01662 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D ShL2_01690 zapA; cell division protein, ZapA K09888 zapA; cell division protein ZapA D ShL2_01171 lytH; N-acetylmuramoyl-L-alanine amidase family protein K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D ShL2_01093 ezrA; septation ring formation regulator K06286 ezrA; septation ring formation regulator D ShL2_01655 cell-division initiation protein K04074 divIVA; cell division initiation protein D ShL2_01658 sepF; cell division-like FtsZ-interacting protein K09772 sepF; cell division inhibitor SepF D ShL2_01154 mreC; cell shape determining protein MreC K03570 mreC; rod shape-determining protein MreC D ShL2_01155 mreD; cell shape determining protein MreD K03571 mreD; rod shape-determining protein MreD D ShL2_00843 FtsW/RodA/SpoVE family cell division protein K05837 rodA; rod shape determining protein RodA D ShL2_02164 CobQ/CobB/MinD/ParA nucleotide binding domain protein K03496 parA; chromosome partitioning protein D ShL2_02430 parB; chromosome/plasmid partitioning protein ParB K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D ShL2_02453 noc; ParB family nucleoid occlusion protein, Noc K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D ShL2_01430 parC; DNA topoisomerase (ATP-hydrolyzing) ParC K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D ShL2_01431 gyrB_2; DNA topoisomerase subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D ShL2_02455 gidA; glucose inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D ShL2_02454 gidB; glucose inhibited division protein B K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D ShL2_01596 gid; tRNA (uracil-5-)-methyltransferase Gid K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74] D ShL2_01595 xerC; site-specific recombinase XerC K03733 xerC; integrase/recombinase XerC D ShL2_01304 xerD; site-specific recombinase XerD K04763 xerD; integrase/recombinase XerD D ShL2_02291 mazG_2; nucleoside triphosphate pyrophosphohydrolase K02499 yabN; tetrapyrrole methylase family protein / MazG family protein D ShL2_00768 chromosome partitioning ATPase K03593 mrp; ATP-binding protein involved in chromosome partitioning D ShL2_01137 engB; ribosome biogenesis GTP-binding protein YsxC K03978 engB; GTP-binding protein D ShL2_01976 whiA_2; sporulation regulator WhiA K09762 whiA; cell division protein WhiA C 03400 DNA repair and recombination proteins [BR:shh03400] D ShL2_00406 ada; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D ShL2_02051 phrB; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D ShL2_02206 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D ShL2_00614 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] D ShL2_00978 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D ShL2_01343 nth; DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D ShL2_01020 NUDIX family hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D ShL2_02240 NADH pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D ShL2_01145 tag; DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] D ShL2_01120 fpg; formamidopyrimidine-DNA glycosidase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] D ShL2_01241 nfo; deoxyribonuclease IV (phage-T(4)-induced) K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D ShL2_01167 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D ShL2_00935 lig; DNA ligase (polydeoxyribonucleotide syntase) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D ShL2_01119 DNA-directed DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D ShL2_01984 uvrA_2; excision endonuclease subunit UvrA K03701 uvrA; excinuclease ABC subunit A D ShL2_01985 uvrB; excision endonuclease subunit UvrB K03702 uvrB; excinuclease ABC subunit B D ShL2_00934 pcrA; ATP-dependent DNA helicase, PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D ShL2_02251 rpoB_1; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D ShL2_02250 rpoC; DNA-directed RNA polymerase beta' chain protein K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D ShL2_00727 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D ShL2_00798 rpoE; DNA-directed RNA polymerase subunit delta K03048 rpoE; DNA-directed RNA polymerase subunit delta D ShL2_01636 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D ShL2_02293 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D ShL2_01547 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS D ShL2_01687 recombination and DNA strand exchange inhibitor protein K07456 mutS2; DNA mismatch repair protein MutS2 D ShL2_01546 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL D ShL2_01276 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D ShL2_01277 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D ShL2_01107 dnaE; DNA-directed DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D ShL2_01583 polC; DNA polymerase III subunit alpha K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D ShL2_00002 dnaN; DNA-directed DNA polymerase beta subunit, DnaN K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D ShL2_01211 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D ShL2_02312 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D ShL2_00945 Exonuclease, RNase T and DNA polymerase III K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D ShL2_02319 dnaX; DNA-directed DNA polymerase III subunit gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D ShL2_00829 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D ShL2_02423 ssb; ssDNA-binding protein K03111 ssb; single-strand DNA-binding protein D ShL2_01522 ssDNA-binding protein K03111 ssb; single-strand DNA-binding protein D ShL2_01182 recD; exodeoxyribonuclease V subunit alpha K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] D ShL2_01562 recA; recombination protein RecA K03553 recA; recombination protein RecA D ShL2_01161 ruvA; crossover junction endodeoxyribonuclease K03550 ruvA; holliday junction DNA helicase RuvA D ShL2_01162 ruvB; crossover junction endodeoxyribonuclease K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D ShL2_01634 priA; primosomal protein N prime K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] D ShL2_01438 sbcC; exonuclease subunit SbcC K03546 sbcC; DNA repair protein SbcC/Rad50 D ShL2_01439 sbcD; DNA repair exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11 D ShL2_02269 radA; DNA repair protein K04485 radA; DNA repair protein RadA/Sms D ShL2_00004 recF; DNA repair and genetic recombination protein K03629 recF; DNA replication and repair protein RecF D ShL2_01619 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D ShL2_01232 recO; recombinational DNA repair protein (RecF pathway) K03584 recO; DNA repair protein RecO (recombination protein O) D ShL2_02317 recR; recombination protein K06187 recR; recombination protein RecR D ShL2_01280 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N) D ShL2_01346 recU; Holliday junction-specific endonuclease K03700 recU; recombination protein U D ShL2_01845 addA; ATP-dependent nuclease subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-] D ShL2_01846 addB; ATP-dependent nuclease subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-] D ShL2_00006 gyrA; DNA topoisomerase (ATP-hydrolyzing) subunit A, GyrA K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D ShL2_00005 gyrB_1; DNA topoisomerase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D ShL2_01597 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D ShL2_01323 histone family protein DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta D ShL2_01314 recQ; ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] D ShL2_02024 ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] D ShL2_00944 dinP; DNA-directed DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7] D ShL2_01422 ImpB/MucB/SamB family DNA-damage repair protein K03502 umuC; DNA polymerase V D ShL2_01445 lexA; DNA damage-inducible repressor K01356 lexA; repressor LexA [EC:3.4.21.88] D ShL2_01688 bifunctional DNA polymerase / phosphoesterase K02347 polX; DNA polymerase (family X) D ShL2_01340 dinG; DNA polymerase III, epsilon subunit/ATP-dependent helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D ShL2_02013 nrdE; ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D ShL2_02012 nrdF; ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D ShL2_01106 exopolyphosphatase-like protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] C 03029 Mitochondrial biogenesis [BR:shh03029] D ShL2_01578 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2 D ShL2_01129 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3 D ShL2_01590 tsf; translation elongation factor Ts K02357 tsf; elongation factor Ts D ShL2_02245 tuf; translational elongation factor TU K02358 tuf; elongation factor Tu D ShL2_02246 fus; translational elongation factor G K02355 fusA; elongation factor G D ShL2_01231 era; GTP-binding protein Era K03595 era; GTPase D ShL2_01080 tyrS; tyrosyl-tRNA synthetase, TyrS K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D ShL2_01047 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D ShL2_01173 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D ShL2_01233 glyS; glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D ShL2_02142 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D ShL2_00939 gatA; Aspartyl/glutamyl-tRNA amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D ShL2_00940 gatB; Aspartyl/glutamyl-tRNA amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D ShL2_00938 gatC; bifunctional aspartyl/glutamyl-tRNA amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D ShL2_00829 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D ShL2_02423 ssb; ssDNA-binding protein K03111 ssb; single-strand DNA-binding protein D ShL2_01522 ssDNA-binding protein K03111 ssb; single-strand DNA-binding protein D ShL2_01218 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK D ShL2_01217 grpE; heat shock molecular chaperone protein K03687 GRPE; molecular chaperone GrpE D ShL2_00891 groEL; co-chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D ShL2_00890 groES; co-chaperonin GroES K04078 groES; chaperonin GroES D ShL2_01219 dnaJ; chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ D ShL2_01094 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D ShL2_01179 nifS; cysteine desulfurase, NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D ShL2_00768 chromosome partitioning ATPase K03593 mrp; ATP-binding protein involved in chromosome partitioning D ShL2_01706 ctaB; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] D ShL2_01707 ctaA; cytochrome oxidase assembly protein K02259 COX15; heme a synthase [EC:1.17.99.9] D ShL2_00835 oxaI_2; OxaI/YidC membrane insertion protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D ShL2_00518 oxaI_1; OxaI/YidC membrane insertion protein K03217 yidC; YidC/Oxa1 family membrane protein insertase B B 09183 Protein families: signaling and cellular processes C 02000 Transporters [BR:shh02000] D ShL2_00980 msbA; Lipid A export ATP-binding/permease MsbA K24708 K24708; ATP-binding cassette, subfamily B, putative efflux pump [EC:7.6.2.-] D ShL2_02102 abcA; ABC superfamily ATP binding cassette transporter, ABC protein K18104 abcA; ATP-binding cassette, subfamily B, bacterial AbcA/BmrA [EC:7.6.2.2] D ShL2_02056 ABC superfamily ATP binding cassette transporter, ABC protein K16012 cydC; ATP-binding cassette, subfamily C, bacterial CydC D ShL2_02057 ABC superfamily ATP binding cassette transporter, ABC protein K16013 cydD; ATP-binding cassette, subfamily C, bacterial CydD D ShL2_02152 ABC transporter ATP-binding protein K18231 msr; macrolide transport system ATP-binding/permease protein D ShL2_00671 modA; molybdenum (Mo2+) ABC superfamily ATP binding cassette transporter, binding protein K02020 modA; molybdate transport system substrate-binding protein D ShL2_00672 modB; molybdenum (Mo2+) ABC superfamily ATP binding cassette transporter, membrane protein K02018 modB; molybdate transport system permease protein D ShL2_00674 modC_2; molybdenum (Mo2+) ABC superfamily ATP binding cassette transporter, ABC protein K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5] D ShL2_01721 potD; spermidine/putrescine ABC superfamily ATP binding cassette transporter, binding protein K11069 potD; spermidine/putrescine transport system substrate-binding protein D ShL2_01722 potC; binding-protein-dependent transport system innermembrane protein K11070 potC; spermidine/putrescine transport system permease protein D ShL2_01723 potB; binding-protein-dependent transport system innermembrane protein K11071 potB; spermidine/putrescine transport system permease protein D ShL2_01724 potA; putrescine/spermidine ABC transporter ATPase K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11] D ShL2_00265 gbuC; Glycine betaine/carnitine transport binding protein GbuC precursor K02002 proX; glycine betaine/proline transport system substrate-binding protein D ShL2_00507 opuCC; glycine betaine/L-proline ABC superfamily ATP binding cassette transporter, binding protein K05845 opuC; osmoprotectant transport system substrate-binding protein D ShL2_02022 ABC-type proline/glycine betaine transport systems, permease component K05845 opuC; osmoprotectant transport system substrate-binding protein D ShL2_00506 opuCB; glycine betaine/choline ABC superfamily ATP binding cassette transporter, membrane protein K05846 opuBD; osmoprotectant transport system permease protein D ShL2_00508 opuCD; glycine betaine/L-proline ABC superfamily ATP binding cassette transporter, membrane protein K05846 opuBD; osmoprotectant transport system permease protein D ShL2_00505 opuCA; glycine betaine/choline ABC superfamily ATP binding cassette transporter, ABC protein K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9] D ShL2_00105 rbsR_1; sugar-binding transcriptional regulator, LacI K10439 rbsB; ribose transport system substrate-binding protein D ShL2_00104 rbsC; Ribose transport system permease protein RbsC K10440 rbsC; ribose transport system permease protein D ShL2_00103 ABC transporter ATP-binding protein K10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7] D ShL2_00496 ABC superfamily ATP binding cassette transporter, membrane protein K02069 STAR2; UDP-glucose/iron transport system permease protein D ShL2_00495 ABC superfamily ATP binding cassette transporter, ABC protein K02068 STAR1; UDP-glucose/iron transport system ATP-binding protein D ShL2_01401 pstS; phosphate ABC transporter periplasmic protein K02040 pstS; phosphate transport system substrate-binding protein D ShL2_01402 pstC; phosphate ABC superfamily ATP binding cassette transporter, membrane protein K02037 pstC; phosphate transport system permease protein D ShL2_01403 pstA; phosphate ABC superfamily ATP binding cassette transporter, membrane protein K02038 pstA; phosphate transport system permease protein D ShL2_01404 pstB; phosphate ABC superfamily ATP binding cassette transporter, ABC protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D ShL2_00235 phnD_1; phosphate/phosphonate ABC transporter periplasmic protein K02044 phnD; phosphonate transport system substrate-binding protein D ShL2_00443 phnD_2; phosphate/phosphonate ABC transporter periplasmic protein K02044 phnD; phosphonate transport system substrate-binding protein D ShL2_00237 ABC superfamily ATP binding cassette transporter, membrane protein K02042 phnE; phosphonate transport system permease protein D ShL2_00238 ABC superfamily ATP binding cassette transporter, membrane protein K02042 phnE; phosphonate transport system permease protein D ShL2_00236 phnC; phosphonate ABC transporter ATP-binding protein K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2] D ShL2_00538 amino acid ABC superfamily ATP binding cassette transporter, binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D ShL2_00539 ABC transporter ATP-binding protein K10009 tcyB; L-cystine transport system permease protein D ShL2_00540 ABC superfamily ATP binding cassette transporter, ABC protein K10010 tcyC; L-cystine transport system ATP-binding protein [EC:7.4.2.1] D ShL2_00988 polar amino acid ABC transporter inner membrane subunit K17077 artQ; arginine/lysine/histidine transport system permease protein D ShL2_00989 glnQ; glutamate ABC superfamily ATP binding cassette transporter, ABC protein K23060 artR; arginine/lysine/histidine transport system ATP-binding protein [EC:7.4.2.1] D ShL2_01902 ABC superfamily ATP binding cassette transporter, binding protein K02073 metQ; D-methionine transport system substrate-binding protein D ShL2_00361 ABC superfamily ATP binding cassette transporter, binding protein K02073 metQ; D-methionine transport system substrate-binding protein D ShL2_01903 binding-protein-dependent transport system innermembrane protein K02072 metI; D-methionine transport system permease protein D ShL2_01904 DL-methionine transporter ATP-binding subunit K02071 metN; D-methionine transport system ATP-binding protein D ShL2_01829 opp3A; oligopeptide ABC superfamily ATP binding cassette transporter, binding protein, Opp3A K15580 oppA; oligopeptide transport system substrate-binding protein D ShL2_01833 oppB; oligopeptide ABC superfamily ATP binding cassette transporter, membrane protein K15581 oppB; oligopeptide transport system permease protein D ShL2_01832 oppC; oligopeptide ABC superfamily ATP binding cassette transporter, membrane protein K15582 oppC; oligopeptide transport system permease protein D ShL2_01831 oppD; oligopeptide ABC superfamily ATP binding cassette transporter, ABC protein K15583 oppD; oligopeptide transport system ATP-binding protein D ShL2_01830 oppF; oligopeptide ABC superfamily ATP binding cassette transporter, ABC protein K10823 oppF; oligopeptide transport system ATP-binding protein D ShL2_00074 opp-1A_1; oligopeptide ABC superfamily ATP binding cassette transporter, binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D ShL2_00210 opp-1A_2; oligopeptide ABC superfamily ATP binding cassette transporter, binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D ShL2_00209 opp-2B_2; oligopeptide ABC superfamily ATP binding cassette transporter, membrane protein K02033 ABC.PE.P; peptide/nickel transport system permease protein D ShL2_00075 opp-2B_1; oligopeptide ABC superfamily ATP binding cassette transporter, membrane protein K02033 ABC.PE.P; peptide/nickel transport system permease protein D ShL2_00076 opp-2C_1; oligopeptide ABC superfamily ATP binding cassette transporter, membrane protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein D ShL2_00208 opp-2C_2; oligopeptide ABC superfamily ATP binding cassette transporter, membrane protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein D ShL2_00207 opp-1D_2; oligopeptide ABC superfamily ATP binding cassette transporter, ABC protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D ShL2_00077 opp-1D_1; oligopeptide ABC superfamily ATP binding cassette transporter, ABC protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D ShL2_00078 ABC superfamily ATP binding cassette transporter, ABC protein K02032 ddpF; peptide/nickel transport system ATP-binding protein D ShL2_00756 fecB; iron-dicitrate transporter substrate-binding subunit, FecB K23181 fecB; ferric citrate transport system substrate-binding protein D ShL2_00758 htsC; iron (Fe3+) ABC superfamily ATP binding cassettetransporter, membrane protein K23182 fecD; ferric citrate transport system permease protein D ShL2_00757 iron compound ABC transporter permease K23183 fecC; ferric citrate transport system permease protein D ShL2_00666 fhuD; iron (Fe+3) ABC superfamily ATP binding cassettetransporter, binding protein K25308 fhuD; ferric hydroxamate/heme transport system substrate-binding protein D ShL2_02094 fhuB; iron (Fe3+) ABC superfamily ATP binding cassettetransporter, membrane protein K25288 fhuB; ferric hydroxamate/heme transport system permease protein D ShL2_02093 fecD; iron-dicitrate transporter subunit FecD K25289 fhuG; ferric hydroxamate/heme transport system permease protein D ShL2_02095 fhuA; iron (Fe3+) ABC superfamily ATP binding cassettetransporter, ABC protein K25290 fhuA; ferric hydroxamate/heme transport system ATP-binding protein [EC:7.2.2.16] D ShL2_01408 ABC-type siderophore binding protein K25282 yclQ; iron-siderophore transport system substrate-binding protein D ShL2_02010 sstB; iron (Fe+3) ABC superfamily ATP binding cassettetransporter, membrane protein K25283 yclO; iron-siderophore transport system permease protein D ShL2_02011 sstA; iron (Fe+3) ABC superfamily ATP binding cassettetransporter, membrane protein K25284 yclN; iron-siderophore transport system permease protein D ShL2_02009 sstC; iron (Fe+3) ABC superfamily ATP binding cassettetransporter, ABC protein K25285 yclP; iron-siderophore transport system ATP-binding protein [EC:7.2.2.-] D ShL2_02138 iron (Fe3+) ABC superfamily ATP binding cassettetransporter, binding protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein D ShL2_02137 iron (Fe3+) ABC superfamily ATP binding cassettetransporter, membrane protein K02015 ABC.FEV.P; iron complex transport system permease protein D ShL2_00774 ABC superfamily ATP binding cassette transporter, ABC protein K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-] D ShL2_00068 mntC; ABC superfamily ATP binding cassette transporter, binding protein K19975 mntC; manganese transport system substrate-binding protein D ShL2_00069 mntB; ABC superfamily ATP binding cassette transporter, membrane protein K19976 mntB; manganese transport system permease protein D ShL2_00070 mntA; ABC superfamily ATP binding cassette transporter, ABC protein K19973 mntA; manganese transport system ATP-binding protein [EC:7.2.2.5] D ShL2_00545 ABC superfamily ATP binding cassette transporter, binding protein K09815 znuA; zinc transport system substrate-binding protein D ShL2_00054 ABC superfamily ATP binding cassette transporter, binding protein K09815 znuA; zinc transport system substrate-binding protein D ShL2_00446 ABC superfamily ATP binding cassette transporter, binding protein K09815 znuA; zinc transport system substrate-binding protein D ShL2_01243 mreB; ABC superfamily ATP binding cassette transporter, membrane protein K09816 znuB; zinc transport system permease protein D ShL2_01242 znuC; zinc ABC transporter K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D ShL2_00668 biotin biosynthesis BioY family protein K03523 bioY; biotin transport system substrate-specific component D ShL2_01751 ykoC; ABC superfamily ATP binding cassette transporter, membrane protein K16785 ecfT; energy-coupling factor transport system permease protein D ShL2_00730 cobalt (Co2+) ABC superfamily ATP binding cassette transporter, membrane protein K16785 ecfT; energy-coupling factor transport system permease protein D ShL2_00729 cbiO_1; cobalt transporter ATP-binding subunit K01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D ShL2_01750 ykoD; ABC superfamily ATP binding cassette transporter, ABC protein K01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D ShL2_01749 cobalt ABC transporter permease K16925 ykoE; energy-coupling factor transport system permease protein D ShL2_02108 tagG; teichoic acid ABC superfamily ATP binding cassette transporter, membrane protein K09692 tagG; teichoic acid transport system permease protein D ShL2_00974 ABC-type polysaccharide/polyol phosphate transport system ATPase component-like protein K09693 tagH; teichoic acid transport system ATP-binding protein [EC:7.5.2.4] D ShL2_02109 tagH; Teichoic acid export ATP-binding protein, TagH K09693 tagH; teichoic acid transport system ATP-binding protein [EC:7.5.2.4] D ShL2_00599 hemin import ATP-binding protein K09814 hrtA; hemin transport system ATP-binding protein [EC:7.6.2.-] D ShL2_02446 vraE; ABC transporter permease protein, involved in vancomycin resistance K11632 bceB; bacitracin transport system permease protein D ShL2_02445 vraD; SalX, ABC-type antimicrobial peptide transport system, involved in vancomycin resistance K11631 bceA; bacitracin transport system ATP-binding protein D ShL2_00315 ABC superfamily ATP binding cassette transporter, membrane protein K19084 braE; bacitracin transport system permease protein D ShL2_00314 ABC transporter ATP-binding protein K19083 braD; bacitracin transport system ATP-binding protein D ShL2_02081 permease K19080 vraG; cationic antimicrobial peptide transport system permease protein D ShL2_02082 antimicrobial peptide ABC transporter ATPase K19079 vraF; cationic antimicrobial peptide transport system ATP-binding protein D ShL2_01011 ecsB; ABC-type exoprotein transport system, permease component K25157 ecsB; ABC-2 type transport system permease protein D ShL2_01010 ccmA; multidrug ABC transporter K25158 ecsA; ABC-2 type transport system ATP-binding protein D ShL2_00913 ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein D ShL2_02412 ybhR; Inner membrane transport permease YbhR K01992 ABC-2.P; ABC-2 type transport system permease protein D ShL2_02150 lantibiotic protection ABC transporter permease subunit K01992 ABC-2.P; ABC-2 type transport system permease protein D ShL2_01465 ABC superfamily ATP binding cassette transporter, membrane protein K01992 ABC-2.P; ABC-2 type transport system permease protein D ShL2_00910 ABC superfamily ATP binding cassette transporter, ABC protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D ShL2_00912 ABC superfamily ATP binding cassette transporter, ABC protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D ShL2_02411 ABC superfamily ATP binding cassette transporter, ABC protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D ShL2_02151 ABC superfamily ATP binding cassette transporter, ABC protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D ShL2_01466 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D ShL2_00227 ABC superfamily ATP binding cassette transporter, ABC protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D ShL2_00062 ABC superfamily ATP binding cassette transporter, ABC protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D ShL2_00089 ABC superfamily ATP binding cassette transporter, membrane protein K02004 ABC.CD.P; putative ABC transport system permease protein D ShL2_00090 ABC superfamily ATP binding cassette transporter, binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D ShL2_01897 sufC; ABC superfamily ATP binding cassette transporter, ABC protein K09013 sufC; Fe-S cluster assembly ATP-binding protein D ShL2_02052 divalent anion symporter K14445 SLC13A2_3_5; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5 D ShL2_00576 mepA_1; MATE family multi-antimicrobial extrusion protein K18908 mepA; MATE family, multidrug efflux pump D ShL2_02210 proP; MFS family major facilitator transporter, proline/betaine:cation symporter K03762 proP; MFS transporter, MHS family, proline/betaine transporter D ShL2_00461 MFS family major facilitator transporter, glucarate:cation symporter K03535 gudP; MFS transporter, ACS family, glucarate transporter D ShL2_02179 yycB; transporter YycB K03449 MFS.CP; MFS transporter, CP family, cyanate transporter D ShL2_00561 narK; MFS family major facilitator transporter, nitrate:nitrite antiporter K10850 narT; MFS transporter, NNP family, putative nitrate transporter D ShL2_00603 tcaB_2; MFS family major facilitator transporter, teicoplanin:cation symporter K07552 bcr; MFS transporter, DHA1 family, multidrug resistance protein D ShL2_00528 bcr; MFS family major facilitator transporter, bicyclomycin:cation symporter K07552 bcr; MFS transporter, DHA1 family, multidrug resistance protein D ShL2_02047 norA; multidrug/H+ antiporter K19576 norA; MFS transporter, DHA1 family, quinolone resistance protein D ShL2_00500 MFS family major facilitator transporter, chloramphenicol:cation symporter K18567 pbuE; MFS transporter, DHA1 family, purine base/nucleoside efflux pump D ShL2_00232 MFS family major facilitator transporter, chloramphenicol:cation symporter K19577 ydhP; MFS transporter, DHA1 family, inner membrane transport protein D ShL2_00753 major facilitator superfamily transporter K23448 sfaA; MFS transporter, DHA1 family, staphyloferrin A biosynthesis exporter D ShL2_02388 qacA_2; antiseptic resistance protein K08167 smvA; MFS transporter, DHA2 family, multidrug resistance protein D ShL2_00513 MFS family major facilitator transporter K08170 norB; MFS transporter, DHA2 family, multidrug resistance protein D ShL2_00338 major facilitator superfamily transporter K08170 norB; MFS transporter, DHA2 family, multidrug resistance protein D ShL2_00767 drug resistance transporter EmrB/QacA subfamily protein K18934 lmrS; MFS transporter, DHA2 family, multidrug resistance protein D ShL2_00765 major facilitator superfamily transporter K18935 sdrM; MFS transporter, DHA2 family, multidrug resistance protein D ShL2_00537 MFS family major facilitator transporter, multidrug :cation symporter K18936 mdeA; MFS transporter, DHA2 family, multidrug resistance protein D ShL2_00262 tcaB_1; MFS family major facilitator transporter, teicoplanin:cation symporter K08224 ynfM; MFS transporter, YNFM family, putative membrane transport protein D ShL2_01743 ptsA_2; phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] D ShL2_01744 phosphocarrier protein Hpr K02784 ptsH; phosphocarrier protein HPr D ShL2_01368 crr; phosphotransferase system glucose-specific IIA component K02777 crr; sugar PTS system EIIA component [EC:2.7.1.-] D ShL2_00417 PTS system, glucose-specific IICBA component K20118 ptsG; glucose PTS system EIICBA or EIICB component [EC:2.7.1.199] D ShL2_01085 ptaA; phosphotransferase system, N-acetylglucosamine-specific IIBC component K02804 nagE; N-acetylglucosamine PTS system EIICBA or EIICB component [EC:2.7.1.193] D ShL2_00272 PTS system maltose/glucose-specific IICB component K02791 malX; maltose/glucose PTS system EIICB component [EC:2.7.1.199 2.7.1.208] D ShL2_00571 PTS system sucrose-specific IIBC component K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211] D ShL2_00641 murP; N-acetylmuramic acid phosphotransfer permease K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211] D ShL2_02323 PTS system trehalose-specific IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D ShL2_00632 PTS system glucose-specific IIBC component K02750 glvC; alpha-glucoside PTS system EIICB component [EC:2.7.1.208 2.7.1.-] D ShL2_02042 PTS system D-fructose-specific transporter subunit IIABC K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] D ShL2_00153 mtlA; PTS system mannitol-specific IIBC component K02800 mtlA; mannitol PTS system EIICBA or EIICB component [EC:2.7.1.197] D ShL2_00741 PTS system lactose/cellobiose-specific IIA component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207] D ShL2_00742 PTS system lactose/cellobiose-specific IIBC component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207] D ShL2_00115 PTS system lactose/cellobiose-specific IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D ShL2_00113 licB; Lichenan-specific phosphotransferase enzyme IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D ShL2_00114 PTS system lactose/cellobiose-specific IIBC component K02761 celB; cellobiose PTS system EIIC component D ShL2_02090 dhaM; dihydroxyacetone kinase, phosphotransfer subunit K05881 dhaM; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaM [EC:2.7.1.121] D ShL2_01544 glpF; MIP family major intrinsic protein channel protein K02440 glpF; glycerol uptake facilitator D ShL2_00878 nrgA; AMT family ammonium or ammonia transporter K03320 amt; ammonium transporter, Amt family D ShL2_01437 mscL; large-conductance mechanosensitive channel K03282 mscL; large conductance mechanosensitive channel D ShL2_00050 MscS family small conductance mechanosensitive ion channel protein K22044 ybiO; moderate conductance mechanosensitive channel D ShL2_02429 MscS family small conductance mechanosensitive ion channel protein K22044 ybiO; moderate conductance mechanosensitive channel D ShL2_01811 mgtE; MgtE family magnesium (Mg2+)/cobalt (Co2+) transporter-E K06213 mgtE; magnesium transporter D ShL2_00611 corA_2; magnesium and cobalt transport protein K03284 corA; magnesium transporter D ShL2_00404 corA_1; magnesium and cobalt transport protein K03284 corA; magnesium transporter D ShL2_00572 cobI; Mg2+ transporter protein, CorA family protein K03284 corA; magnesium transporter D ShL2_01026 crcB; camphor resistance protein CrcB K06199 crcB; fluoride exporter D ShL2_02041 Mg2+ and Co2+ transporter, CorB K03699 tlyC; magnesium and cobalt exporter, CNNM family D ShL2_00510 lrgA_2; murein hydrolase regulator K05338 lrgA; holin-like protein D ShL2_00413 lrgA_1; murein hydrolase subunit LrgA_1 K06518 cidA; holin-like protein D ShL2_01128 lysP; APC family amino acid-polyamine-organocation transporter K11733 lysP; lysine-specific permease D ShL2_00522 amino acid permease K11737 cycA; D-serine/D-alanine/glycine transporter D ShL2_00091 D-serine/D-alanine/glycine transporter K11737 cycA; D-serine/D-alanine/glycine transporter D ShL2_01114 D-serine/D-alanine/glycine transporter K11737 cycA; D-serine/D-alanine/glycine transporter D ShL2_00281 arcD; arginine/ornithine APC family amino acid-polyamine-organocation transporter, antiporter K03758 arcD; arginine:ornithine antiporter / lysine permease D ShL2_02407 czrB_2; cation diffusion facilitator family transporter K16264 czcD; cobalt-zinc-cadmium efflux system protein D ShL2_00779 czrB_1; cation diffusion facilitator family transporter K16264 czcD; cobalt-zinc-cadmium efflux system protein D ShL2_02026 zupT; Zinc transporter ZupT K07238 TC.ZIP; zinc transporter, ZIP family D ShL2_00654 ykkC; Multidrug resistance protein YkkC K18924 ykkC; paired small multidrug resistance pump D ShL2_00653 ykkD; Multidrug resistance protein YkkD K18925 ykkD; paired small multidrug resistance pump D ShL2_00695 glcU; DMT superfamily drug/metabolite transporter K05340 glcU; glucose uptake protein D ShL2_00155 rarD; DMT superfamily drug/metabolite transporter K05786 rarD; chloramphenicol-sensitive protein RarD D ShL2_02128 hypothetical protein K09936 TC.BAT2; bacterial/archaeal transporter family-2 protein D ShL2_00617 hypothetical protein K09771 TC.SMR3; small multidrug resistance family-3 protein D ShL2_01869 NhaC family sodium:proton (Na+:H+) antiporter K07084 yuiF; putative amino acid transporter D ShL2_00470 gntP; GntP family gluconate:proton (H+) symporter K03299 TC.GNTP; gluconate:H+ symporter, GntP family D ShL2_00331 dcuA; Anaerobic C4-dicarboxylate transporter DcuA K07791 dcuA; anaerobic C4-dicarboxylate transporter DcuA D ShL2_01436 opuD; BCCT family betaine/carnitine/choline transporter K05020 opuD; glycine betaine transporter D ShL2_00747 betT_2; choline transport protein BetT K05020 opuD; glycine betaine transporter D ShL2_00193 betT_1; choline transport protein BetT K05020 opuD; glycine betaine transporter D ShL2_00937 putP; SSS family solute:sodium (Na+)/proline symporter K11928 putP; sodium/proline symporter D ShL2_00565 gltT; DAACS family dicarboxylate/amino acid:sodium (Na+) or proton (H+) symporter K11102 gltP; proton glutamate symport protein D ShL2_00613 gltS; ESS family glutamate:sodium (Na+) symporter K03312 gltS; glutamate:Na+ symporter, ESS family D ShL2_00658 nhaC; Na+/H+ antiporter K03315 nhaC; Na+:H+ antiporter, NhaC family D ShL2_02114 sodium/hydrogen exchanger family protein K24163 nhaK; monovalent cation/hydrogen antiporter D ShL2_02348 trkG; Trk family potassium (K+) transporter, ABC protein K03498 trkH; trk/ktr system potassium uptake protein D ShL2_01798 trkH; Trk family potassium (K+) transporter, membrane protein K03498 trkH; trk/ktr system potassium uptake protein D ShL2_01737 trkA; NAD+ binding potassium transporter K03499 trkA; trk/ktr system potassium uptake protein D ShL2_01647 uraA; uracil permease K02824 uraA; uracil permease D ShL2_02359 pbuX; NCS2 nucleobase cation symporter, PbuX K16169 pbuX; xanthine permease D ShL2_00698 xanthine/uracil permeases family protein K06901 pbuG; adenine/guanine/hypoxanthine permease D ShL2_02274 nupC; Na+ dependent nucleoside transporter domain-containing protein K11535 nupC; nucleoside transport protein D ShL2_02097 nupC2; Na+ dependent nucleoside transporter domain-containing protein K16323 yxjA; purine nucleoside transport protein D ShL2_00953 nixA; NiCoT family nickel (Ni2+)-cobalt (Co2+) transporter K07241 hoxN; nickel/cobalt transporter (NiCoT) family protein D ShL2_00624 dauA; C4-dicarboxylic acid transporter DauA K03321 TC.SULP; sulfate permease, SulP family D ShL2_01718 Mn2+/Fe2+ transporter NRAMP family protein K03322 mntH; manganese transport protein D ShL2_00124 arsB_3; arsenical pump membrane protein K03893 arsB; arsenical pump membrane protein D ShL2_00026 arsB_1; arsenical pump membrane protein K03893 arsB; arsenical pump membrane protein D ShL2_00047 arsB_2; arsenical pump membrane protein K03893 arsB; arsenical pump membrane protein D ShL2_02124 mnh_A1; monovalent cation/H+ antiporter subunit A, MnhA_1 K05565 mnhA; multicomponent Na+:H+ antiporter subunit A D ShL2_01860 mnhA; monovalent cation antiporter-3 subunit A, MnhA K05565 mnhA; multicomponent Na+:H+ antiporter subunit A D ShL2_02123 mnhB_2; monovalent cation antiporter-3, MnhB_1 K05566 mnhB; multicomponent Na+:H+ antiporter subunit B D ShL2_01861 mnhB_1; CPA3 family monovalent cation:proton (H+) antiporter-3 subunit B K05566 mnhB; multicomponent Na+:H+ antiporter subunit B D ShL2_02122 mnhC_2; monovalent cation antiporter-3, MnhC_1 K05567 mnhC; multicomponent Na+:H+ antiporter subunit C D ShL2_01862 mnhC_1; CPA3 family monovalent cation:proton (H+) antiporter-3 subunit C K05567 mnhC; multicomponent Na+:H+ antiporter subunit C D ShL2_02121 mnhD_2; monovalent cation antiporter-3, MnhD_1 K05568 mnhD; multicomponent Na+:H+ antiporter subunit D D ShL2_01863 mnhD_1; monovalent cation antiporter-3 subunit D, MnhD K05568 mnhD; multicomponent Na+:H+ antiporter subunit D D ShL2_02120 mnhE_2; monovalent cation antiporter-3, MnhE_1 K05569 mnhE; multicomponent Na+:H+ antiporter subunit E D ShL2_01864 mnhE_1; CPA3 family monovalent cation:proton (H+) antiporter-3 subunit E K05569 mnhE; multicomponent Na+:H+ antiporter subunit E D ShL2_02119 mnhF_2; monovalent cation antiporter-3, MnhF_1 K05570 mnhF; multicomponent Na+:H+ antiporter subunit F D ShL2_01865 mnhF_1; CPA3 family monovalent cation:proton (H+) antiporter-3 subunit F K05570 mnhF; multicomponent Na+:H+ antiporter subunit F D ShL2_02118 mnhG_2; monovalent cation antiporter-3, MnhG_1 K05571 mnhG; multicomponent Na+:H+ antiporter subunit G D ShL2_01866 mnhG_1; CPA3 family monovalent cation:proton (H+) antiporter-3 subunit G K05571 mnhG; multicomponent Na+:H+ antiporter subunit G D ShL2_00693 AEC family malonate efflux carrier K24180 mleP; malate permease and related proteins D ShL2_01915 LysE type translocator protein K06895 lysE; L-lysine exporter family protein LysE/ArgO D ShL2_00009 azlC; branched-chain amino acid permease K26605 azlC; branched chain amino acid efflux pump D ShL2_00010 azlD; Branched-chain amino acid transport protein, AzlD K26606 azlD; branched chain amino acid efflux pump D ShL2_01311 riboflavin transporter K23675 fmnP; riboflavin transporter D ShL2_01359 yhhQ; Inner membrane protein YhhQ K09125 yhhQ; queuosine precursor transporter D ShL2_01710 ftsW; cell division membrane protein K03588 ftsW; cell division protein FtsW D ShL2_00585 high-affinity Fe2+/Pb2+ permease-like protein K07243 FTR; high-affinity iron transporter D ShL2_00583 imelysin K07224 efeO; iron uptake system component EfeO D ShL2_00584 TAT-translocated Dyp-type peroxidase K16301 efeB; deferrochelatase/peroxidase EfeB [EC:1.11.1.-] D ShL2_00554 narG; respiratory nitrate reductase subunit alpha K00370 narG; nitrate reductase / nitrite oxidoreductase, alpha subunit [EC:1.7.5.1 1.7.99.-] D ShL2_00555 narY; nitrate reductase subunit beta K00371 narH; nitrate reductase / nitrite oxidoreductase, beta subunit [EC:1.7.5.1 1.7.99.-] D ShL2_00557 narI; respiratory nitrate reductase subunit gamma K00374 narI; nitrate reductase gamma subunit [EC:1.7.5.1 1.7.99.-] D ShL2_00294 cap5B; capsular polysaccharide biosynthesis protein Cap5B K00903 epsB; protein-tyrosine kinase [EC:2.7.10.3] D ShL2_00293 cap5A; capsular polysaccharide biosynthesis protein Cap5A K19420 epsA; protein tyrosine kinase modulator D ShL2_01777 Tryptophan-rich transmembrane signaling protein K05770 TSPO; translocator protein D ShL2_00577 ycnJ; Copper transport protein YcnJ precursor K14166 ycnJ; copper transport protein C 02044 Secretion system [BR:shh02044] D ShL2_01657 YGGT family protein K02221 yggT; YggT family protein D ShL2_01207 comEA_1; competence protein ComEA K02237 comEA; competence protein ComEA D ShL2_01208 comEA_2; competence protein ComEA K02237 comEA; competence protein ComEA D ShL2_01209 comEB; late competence operon required for DNA binding and uptake comEB K01493 comEB; dCMP deaminase [EC:3.5.4.12] D ShL2_01210 comEC; competence protein ComEC K02238 comEC; competence protein ComEC D ShL2_01994 superfamily II DNA/RNA helicase ComFA K02240 comFA; competence protein ComFA D ShL2_01993 comFC; amidophosphoribosyltransferase, ComFC K02242 comFC; competence protein ComFC D ShL2_01255 late competence protein, ComGA K02243 comGA; competence protein ComGA D ShL2_01256 DNA transport mechinery protein K02244 comGB; competence protein ComGB D ShL2_01257 comGC; Competence protein ComGC-like protein K02245 comGC; competence protein ComGC D ShL2_01258 pulG; Type II secretory pathway, pseudopilin PulG K02246 comGD; competence protein ComGD D ShL2_01148 Type 4 prepilin-like proteins leader peptide-processing enzyme K02236 comC; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D ShL2_01789 comK; competence transcription factor ComK K02250 comK; competence protein ComK D ShL2_00249 secA2; Sec family Type I general secretory pathway protein SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D ShL2_01991 secA; Sec family Type I general secretory pathway preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D ShL2_01166 secF; RND superfamily resistance-nodulation-cell division protein:proton (H+) antiporter K12257 secDF; SecD/SecF fusion protein D ShL2_02260 secE; preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE D ShL2_01960 secG; preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG D ShL2_00721 secY_2; Sec family Type I general secretory pathway preprotein translocase SecY_1 K03076 secY; preprotein translocase subunit SecY D ShL2_00246 secY_1; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D ShL2_01609 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D ShL2_01611 ftsY; cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor D ShL2_01165 yajC; Sec family Type I general secretory pathway preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC D ShL2_00835 oxaI_2; OxaI/YidC membrane insertion protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D ShL2_00518 oxaI_1; OxaI/YidC membrane insertion protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D ShL2_00248 asp2; accessory secretory protein Asp2 K12269 asp2; accessory secretory protein Asp2 D ShL2_00587 tatA; twin-arginine translocation protein, TatA/E family subunit K03116 tatA; sec-independent protein translocase protein TatA D ShL2_00586 tatC_1; Sec-independent periplasmic protein translocase K03118 tatC; sec-independent protein translocase protein TatC C 02042 Bacterial toxins [BR:shh02042] D ShL2_02041 Mg2+ and Co2+ transporter, CorB K03699 tlyC; magnesium and cobalt exporter, CNNM family D ShL2_00764 hemolysin III channel protein K11068 hlyIII; hemolysin III C 02022 Two-component system [BR:shh02022] D ShL2_01118 phoR; alkaline phosphatase synthesis sensor protein PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D ShL2_01117 ompR; response regulator OmpR K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP D ShL2_01310 srrB_2; integral membrane sensor signal transduction histidine kinase K07651 resE; two-component system, OmpR family, sensor histidine kinase ResE [EC:2.7.13.3] D ShL2_01309 srrA_2; winged helix family two component transcriptional regulator K07775 resD; two-component system, OmpR family, response regulator ResD D ShL2_00018 walK; multi-sensor signal transduction histidine kinase, WalK K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3] D ShL2_00017 walR; transcriptional regulator WalR K07668 vicR; two-component system, OmpR family, response regulator VicR D ShL2_00313 integral membrane sensor signal transduction histidine kinase K19081 braS; two-component system, OmpR family, sensor histidine kinase BraS/BceS [EC:2.7.13.3] D ShL2_00312 winged helix family two component transcriptional regulator K19082 braR; two-component system, OmpR family, response regulator protein BraR/BceR D ShL2_02083 graS; sensor histidine kinase, GraS K19077 graS; two-component system, OmpR family, sensor histidine kinase GraS [EC:2.7.13.3] D ShL2_02084 graR; winged helix family two component transcriptional regulator K19078 graR; two-component system, OmpR family, response regulator protein GraR D ShL2_01375 arlS; signal transduction histidine kinase K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3] D ShL2_01374 arlR_2; response regulator receiver K18941 arlR; two-component system, OmpR family, response regulator ArlR D ShL2_00595 hssS; integral membrane sensor signal transduction histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3] D ShL2_00596 hssR; winged helix family two component transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator D ShL2_01464 sensor histidine kinase K07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3] D ShL2_01463 response regulator K07693 desR; two-component system, NarL family, response regulator DesR D ShL2_00957 vraS; integral membrane sensor signal transduction histidine kinase K07681 vraS; two-component system, NarL family, vancomycin resistance sensor histidine kinase VraS [EC:2.7.13.3] D ShL2_00958 vraR; LuxR family two component transcriptional regulator K07694 vraR; two-component system, NarL family, vancomycin resistance associated response regulator VraR D ShL2_00559 nreB; oxygen sensor histidine kinase nreB K07683 nreB; two-component system, NarL family, sensor histidine kinase NreB [EC:2.7.13.3] D ShL2_00560 nreC; LuxR family two component transcriptional regulator K07696 nreC; two-component system, NarL family, response regulator NreC D ShL2_00997 yhcS; two-component response regulator sensor protein,histidine kinase K02480 K02480; two-component system, NarL family, sensor kinase [EC:2.7.13.3] D ShL2_00998 yhcR; two-component response regulator receiver protein K02479 K02479; two-component system, NarL family, response regulator D ShL2_00511 lytR; two component transcriptional regulator, LytR K07705 lytT; two-component system, LytTR family, response regulator LytT D ShL2_00883 accessory gene regulator protein C K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D ShL2_00882 agrA; autoinducer sensor protein response regulator protein K07707 agrA; two-component system, LytTR family, response regulator AgrA C 02035 Bacterial motility proteins [BR:shh02035] D ShL2_00538 amino acid ABC superfamily ATP binding cassette transporter, binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D ShL2_02396 hypothetical protein K02382 flbA; flagellar protein FlbA C 03037 Cilium and associated proteins C 04812 Cytoskeleton proteins [BR:shh04812] D ShL2_01662 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D ShL2_01663 ftsA; cell division protein K03590 ftsA; cell division protein FtsA D ShL2_02164 CobQ/CobB/MinD/ParA nucleotide binding domain protein K03496 parA; chromosome partitioning protein D ShL2_02430 parB; chromosome/plasmid partitioning protein ParB K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D ShL2_02453 noc; ParB family nucleoid occlusion protein, Noc K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein C 04147 Exosome [BR:shh04147] D ShL2_00355 fdaB; fructose-bisphosphate aldolase K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D ShL2_01962 eno; enolase (2-phosphoglycerate dehydrogenase) K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D ShL2_01966 gap; glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D ShL2_01965 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D ShL2_01112 pykA; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D ShL2_00891 groEL; co-chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D ShL2_01218 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK D ShL2_01850 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D ShL2_02358 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D ShL2_02245 tuf; translational elongation factor TU K02358 tuf; elongation factor Tu D ShL2_01009 hit; HIT family hydrolase K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D ShL2_00421 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D ShL2_02213 vraA; long chain fatty acid CoA ligase, VraA K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D ShL2_02212 vraB; acetyl-CoA C-acetyltransferase VraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D ShL2_00408 paaJ; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D ShL2_00722 adk; Nucleoside-triphosphate--adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D ShL2_01168 apt; adenine phosphoribosyl transferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D ShL2_01852 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D ShL2_01851 argG; argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D ShL2_01543 glpK; glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30] D ShL2_01534 glnA; glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D ShL2_01142 hemB; delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D ShL2_00309 phoA; alkaline phosphatase PhoA K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1] D ShL2_01087 serA; D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D ShL2_01753 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D ShL2_01727 pdhD_4; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00146 pdhD_2; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_00150 pdhD_3; dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_01281 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D ShL2_01293 zwf; glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D ShL2_01964 tpi; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D ShL2_00535 gpm; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D ShL2_02370 phosphoglycerate mutase family protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] C 02048 Prokaryotic defense system [BR:shh02048] D ShL2_01098 Adenine-specific DNA methylase-like protein K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] D ShL2_00035 endonuclease K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-] D ShL2_01503 phage HNH endonuclease K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-] D ShL2_00853 mazF; Toxin MazF K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] D ShL2_00852 mazE; Antitoxin MazE K07723 ndoAI; CopG family transcriptional regulator / antitoxin EndoAI D ShL2_01662 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D ShL2_01430 parC; DNA topoisomerase (ATP-hydrolyzing) ParC K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D ShL2_01431 gyrB_2; DNA topoisomerase subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D ShL2_02170 hypothetical protein K19167 abiQ; protein AbiQ D ShL2_01094 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D ShL2_01179 nifS; cysteine desulfurase, NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7] C 04030 G protein-coupled receptors C 04050 Cytokine receptors C 04054 Pattern recognition receptors C 03310 Nuclear receptors C 04040 Ion channels C 04031 GTP-binding proteins C 04052 Cytokines and neuropeptides C 04515 Cell adhesion molecules C 04090 CD molecules C 01504 Antimicrobial resistance genes [BR:shh01504] D ShL2_01559 bifunctional acetyltransferase/phosphotransferase K19883 aacA-aphD; bifunctional aminoglycoside 6'-N-acetyltransferase / aminoglycoside 2''-phosphotransferase [EC:2.3.1.82 2.7.1.190] D ShL2_02166 acetyltransferase K19273 sat4; streptothricin acetyltransferase [EC:2.3.-.-] D ShL2_02167 aphA; Aminoglycoside 3'-phosphotransferase K19299 aph3-III; aminoglycoside 3'-phosphotransferase III [EC:2.7.1.95] D ShL2_02152 ABC transporter ATP-binding protein K18231 msr; macrolide transport system ATP-binding/permease protein D ShL2_02153 Phosphotransferase enzyme family protein K06979 mph; macrolide phosphotransferase D ShL2_01296 dfrA_1; trimethoprim-sensitive dihydrofolate reductase K18591 dfrD; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3] D ShL2_02388 qacA_2; antiseptic resistance protein K08167 smvA; MFS transporter, DHA2 family, multidrug resistance protein D ShL2_00029 mecA; penicillin-binding protein 2 prime K02545 mecA; penicillin-binding protein 2 prime [EC:3.4.16.4] D ShL2_02381 blaR1; beta-lactamase regulatory protein K02172 blaR1; bla regulator protein blaR1 D ShL2_02382 transcriptional repressor K02171 blaI; BlaI family transcriptional regulator, penicillinase repressor D ShL2_02380 blaZ; beta-lactamase precursor, BlaZ K18766 blaZ; beta-lactamase class A BlaZ [EC:3.5.2.6] D ShL2_00111 vanY; D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D ShL2_02055 MarR family transcriptional regulator K18906 mgrA; MarR family transcriptional regulator, multiple gene regulator MgrA D ShL2_02083 graS; sensor histidine kinase, GraS K19077 graS; two-component system, OmpR family, sensor histidine kinase GraS [EC:2.7.13.3] D ShL2_02084 graR; winged helix family two component transcriptional regulator K19078 graR; two-component system, OmpR family, response regulator protein GraR D ShL2_01880 dltB; D-alanine membrane transfer protein K03739 dltB; membrane protein involved in D-alanine export D ShL2_01879 dltC; D-alanine-activating enzyme/D-alanine-D-alanyl, dltC protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D ShL2_01878 dltD; D-alanine lipoteichoic acid and wall teichoic acid esterification secreted protein K03740 dltD; D-alanine transfer protein D ShL2_01426 fmtC; oxacillin resistance-related FmtC protein K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3] D ShL2_02082 antimicrobial peptide ABC transporter ATPase K19079 vraF; cationic antimicrobial peptide transport system ATP-binding protein D ShL2_02081 permease K19080 vraG; cationic antimicrobial peptide transport system permease protein D ShL2_02102 abcA; ABC superfamily ATP binding cassette transporter, ABC protein K18104 abcA; ATP-binding cassette, subfamily B, bacterial AbcA/BmrA [EC:7.6.2.2] D ShL2_00513 MFS family major facilitator transporter K08170 norB; MFS transporter, DHA2 family, multidrug resistance protein D ShL2_00338 major facilitator superfamily transporter K08170 norB; MFS transporter, DHA2 family, multidrug resistance protein D ShL2_02387 qacR; transcriptional regulator QacR K18938 qacR; TetR/AcrR family transcriptional regulator, repressor for qacA D ShL2_00575 mepR; mepA/mepB repressor and autoregulator K18909 mepR; MarR family transcriptional regulator, repressor for mepA D ShL2_00576 mepA_1; MATE family multi-antimicrobial extrusion protein K18908 mepA; MATE family, multidrug efflux pump C 00535 Proteoglycans C 00536 Glycosaminoglycan binding proteins C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:shh00537] D ShL2_00309 phoA; alkaline phosphatase PhoA K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1] C 04091 Lectins C 04990 Domain-containing proteins not elsewhere classified B B 09185 Viral protein families C 03200 Viral proteins [BR:shh03200] C 03210 Viral fusion proteins B B 09184 RNA family C 03100 Non-coding RNAs [BR:shh03100] D ShL2_t00012 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D ShL2_t00052 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D ShL2_t00021 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D ShL2_t00047 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D ShL2_t00019 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D ShL2_t00054 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D ShL2_t00050 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D ShL2_t00003 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D ShL2_t00048 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D ShL2_t00044 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D ShL2_t00025 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D ShL2_t00028 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D ShL2_t00040 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D ShL2_t00002 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D ShL2_t00035 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D ShL2_t00007 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D ShL2_t00034 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D ShL2_t00045 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D ShL2_t00001 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D ShL2_t00004 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D ShL2_t00017 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D ShL2_t00056 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D ShL2_t00010 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D ShL2_t00043 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D ShL2_t00036 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D ShL2_t00037 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D ShL2_t00042 tRNA-His K14226 tRNA-His; tRNA His D ShL2_t00033 tRNA-His K14226 tRNA-His; tRNA His D ShL2_t00011 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D ShL2_t00051 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D ShL2_t00018 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D ShL2_t00055 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D ShL2_t00016 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D ShL2_t00038 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D ShL2_t00009 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D ShL2_t00008 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D ShL2_t00015 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D ShL2_t00057 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D ShL2_t00027 tRNA-Met K14230 tRNA-Met; tRNA Met D ShL2_t00039 tRNA-Met K14230 tRNA-Met; tRNA Met D ShL2_t00023 tRNA-Met K14230 tRNA-Met; tRNA Met D ShL2_t00022 tRNA-Met K14230 tRNA-Met; tRNA Met D ShL2_t00029 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D ShL2_t00041 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D ShL2_t00020 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D ShL2_t00053 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D ShL2_t00026 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D ShL2_t00060 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D ShL2_t00024 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D ShL2_t00049 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D ShL2_t00046 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D ShL2_t00014 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D ShL2_t00030 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D ShL2_t00058 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D ShL2_t00032 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D ShL2_t00006 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D ShL2_t00031 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D ShL2_t00005 tRNA-Val K14237 tRNA-Val; tRNA Val D ShL2_t00059 tRNA-Val K14237 tRNA-Val; tRNA Val D ShL2_t00013 tRNA-Val K14237 tRNA-Val; tRNA Val D ShL2_r00001 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D ShL2_r00012 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D ShL2_r00016 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D ShL2_r00007 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D ShL2_r00004 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D ShL2_r00005 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D ShL2_r00011 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D ShL2_r00002 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D ShL2_r00008 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D ShL2_r00015 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D ShL2_r00003 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D ShL2_r00006 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D ShL2_r00013 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D ShL2_r00010 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D ShL2_r00009 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D ShL2_r00014 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA # A09190 Not Included in Pathway or Brite B B 09191 Unclassified: metabolism C 99980 Enzymes with EC numbers D ShL2_02188 oxidoreductase, aldo/keto reductase family K06607 iolS; myo-inositol catabolism protein IolS [EC:1.1.1.-] D ShL2_00147 acoA_1; 2-oxoisovalerate dehydrogenase subunit alpha K21416 acoA; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha [EC:1.1.1.-] D ShL2_00148 bfmBAB_1; 2-oxoisovalerate dehydrogenase, E1 component, beta subunit K21417 acoB; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta [EC:1.1.1.-] D ShL2_01301 aldo/keto oxidoreductase K23107 yajO; 1-deoxyxylulose-5-phosphate synthase [EC:1.1.-.-] D ShL2_00657 NAD/NADP octopine/nopaline dehydrogenase family protein K04940 odh; opine dehydrogenase [EC:1.5.1.28] D ShL2_00042 NADP-dependent zinc-binding dehydrogenase K00359 qorA; NADPH:quinone reductase [EC:1.6.5.5] D ShL2_00291 azoR; FMN-dependent NADH-azoreductase, AzoR K01118 acpD; FMN-dependent NADH-azoreductase [EC:1.7.1.17] D ShL2_01842 coenzyme A disulfide reductase K08255 cdr; CoA-disulfide reductase [EC:1.8.1.14] D ShL2_02368 ahpF; alkyl hydroperoxide reductase, large subunit K03387 ahpF; NADH-dependent peroxiredoxin subunit F [EC:1.8.1.-] D ShL2_01317 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K26960 bdr; bacillithiol disulfide reductase [EC:1.8.1.-] D ShL2_01425 peptide methionine sulfoxide reductase K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11] D ShL2_01366 peptide methionine sulfoxide reductase II K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11] D ShL2_00258 msrA; methionine sulfoxide reductase A, MsrA K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11] D ShL2_01367 msrB; peptide methionine sulfoxide reductase MsrB K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12] D ShL2_00984 bcp; alkyl hydroperoxide reductase K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24] D ShL2_01097 tpx; thiol peroxidase K11065 tpx; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24] D ShL2_02367 ahpC; alkyl hydroperoxide reductase subunit C K24119 ahpC; NADH-dependent peroxiredoxin subunit C [EC:1.11.1.26] D ShL2_01913 osmC; osmotically inducible protein OsmC K04063 osmC; lipoyl-dependent peroxiredoxin [EC:1.11.1.28] D ShL2_01764 nitric oxide dioxygenase K05916 hmp; nitric oxide dioxygenase [EC:1.14.12.17] D ShL2_00946 ftn; ferritin K02217 ftnA; ferritin [EC:1.16.3.2] D ShL2_00580 pyridine nucleotide-disulfide oxidoreductase K21567 fnr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1] D ShL2_00025 arsC_1; arsenate reductase (glutaredoxin) K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4] D ShL2_00046 arsC_2; arsenate reductase (glutaredoxin) K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4] D ShL2_01350 site-specific DNA-methyltransferase (adenine-specific) K07444 ypsC; putative N6-adenine-specific DNA methylase [EC:2.1.1.-] D ShL2_00588 acetyltransferase K22441 paiA; diamine N-acetyltransferase [EC:2.3.1.57] D ShL2_00225 N-hydroxyarylamine O-acetyltransferase K00675 nhoA; N-hydroxyarylamine O-acetyltransferase [EC:2.3.1.118] D ShL2_00038 yjaB_1; N-acetyltransferase YjaB K03826 yiaC; putative acetyltransferase [EC:2.3.1.-] D ShL2_02347 yjaB_2; N-acetyltransferase YjaB K03827 yjaB; putative acetyltransferase [EC:2.3.1.-] D ShL2_01076 acuA; acetoin dehydrogenase-like protein K04766 acuA; acetoin utilization protein AcuA [EC:2.3.1.-] D ShL2_00437 GNAT family acetyltransferase K24217 mnaT; L-amino acid N-acyltransferase [EC:2.3.1.-] D ShL2_01337 lipopolysaccharide biosynthesis-related pr-like protein K00754 bshA; L-malate glycosyltransferase [EC:2.4.1.-] D ShL2_01982 lgt; prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145] D ShL2_01621 dihydroxyacetone kinase family protein K07030 fakA; fatty acid kinase [EC:2.7.2.18] D ShL2_00347 yqfL_1; pyruvate, phosphate dikinase regulatoryprotein K09773 ppsR; [pyruvate, water dikinase]-phosphate phosphotransferase / [pyruvate, water dikinase] kinase [EC:2.7.4.28 2.7.11.33] D ShL2_01235 yqfL_2; pyruvate, phosphate dikinase regulatoryprotein K09773 ppsR; [pyruvate, water dikinase]-phosphate phosphotransferase / [pyruvate, water dikinase] kinase [EC:2.7.4.28 2.7.11.33] D ShL2_00387 thymidylate kinase K23753 ppk2; AMP-polyphosphate phosphotransferase [EC:2.7.4.33] D ShL2_01998 diguanylate cyclase GGDEF domain protein K18967 dge1; diguanylate cyclase [EC:2.7.7.65] D ShL2_00770 disA; checkpoint controller nucleotide-binding protein K18672 dacA; diadenylate cyclase [EC:2.7.7.85] D ShL2_00763 UTP-glucose-1-phosphate uridylyltransferase K11442 K11442; putative uridylyltransferase [EC:2.7.7.-] D ShL2_01983 hprK; HPr(Ser) kinase/phosphatase K06023 hprK; HPr kinase/phosphorylase [EC:2.7.11.- 2.7.4.-] D ShL2_02271 D-isomer specific 2-hydroxyacid dehydrogenase family protein K19405 mcsB; protein arginine kinase [EC:2.7.14.1] D ShL2_02340 esterase/lipase K03928 yvaK; carboxylesterase [EC:3.1.1.1] D ShL2_01959 est; carboxyesterase -like protein K03928 yvaK; carboxylesterase [EC:3.1.1.1] D ShL2_01771 Autolysis and methicillin resistant-related protein K22580 fmtA; teichoic acid D-alanine hydrolase [EC:3.1.1.103] D ShL2_00218 drp35; SMP-30/Gluconolaconase/LRE domain-containing protein K02352 drp35; lactonase [EC:3.1.1.-] D ShL2_00501 pnbA; para-nitrobenzyl esterase chain A K03929 pnbA; para-nitrobenzyl esterase [EC:3.1.1.-] D ShL2_00283 esterase K03930 estA; putative tributyrin esterase [EC:3.1.1.-] D ShL2_00610 bifunctional 3-hydroxyacyl-CoA dehydrogenase/thioesterase K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-] D ShL2_01434 thioesterase K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-] D ShL2_00419 thioesterase K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-] D ShL2_00295 cap5C; capsular polysaccharide biosynthesis protein Cap5C K01104 E3.1.3.48; protein-tyrosine phosphatase [EC:3.1.3.48] D ShL2_01199 haloacid dehalogenase-like hydrolase K07015 yqeG; putative phosphatase [EC:3.1.3.-] D ShL2_00013 bifunctional signaling protein/50S ribosomal protein L9 K22927 gdpP; cyclic-di-AMP phosphodiesterase [EC:3.1.4.59] D ShL2_02305 tatP; Mg-dependent DNase K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D ShL2_02304 ribonuclease M5 K05985 rnmV; ribonuclease M5 [EC:3.1.26.8] D ShL2_01620 staphylococcal thermonuclease precursor K01174 nuc; micrococcal nuclease [EC:3.1.31.1] D ShL2_01460 thermonuclease precursor family protein K01174 nuc; micrococcal nuclease [EC:3.1.31.1] D ShL2_01480 cwlA; N-acetylmuramoyl-L-alanine amidase CwlA precursor K01447 xlyAB; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D ShL2_02332 N-acetylmuramoyl-L-alanine amidase K22409 sle1; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D ShL2_01732 def; polypeptide deformylase 2 K01462 PDF; peptide deformylase [EC:3.5.1.88] D ShL2_01632 def2; polypeptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88] D ShL2_02299 endoribonuclease L-PSP K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10] D ShL2_00811 low molecular weight protein-tyrosine-phosphatase K20201 ywlE; protein arginine phosphatase [EC:3.9.1.2] D ShL2_01016 ydeN; hydrolase YdeN K07002 RBBP9; serine hydrolase [EC:3.-.-.-] D ShL2_00377 amidohydrolase K22213 PATG; 6-methylsalicylate decarboxylase [EC:4.1.1.52] D ShL2_00223 myosin-cross-reactive antigen K10254 ohyA; oleate hydratase [EC:4.2.1.53] D ShL2_00007 carbohydrate kinase K17758 nnrD; ADP-dependent NAD(P)H-hydrate dehydratase [EC:4.2.1.136] D ShL2_00427 capB; Capsule biosynthesis protein CapB K01932 capB; gamma-polyglutamate synthase [EC:6.3.2.-] D ShL2_00794 hypothetical protein K27344 ldmS; L-aspartate-L-methionine ligase [EC:6.3.2.-] D ShL2_00033 copA_1; P-ATPase superfamily P-type ATPase copper (Cu2+)transporter K01533 copB; P-type Cu2+ transporter [EC:7.2.2.9] C 99981 Carbohydrate metabolism D ShL2_01075 acuC; histone deacetylase family protein K04768 acuC; acetoin utilization protein AcuC D ShL2_01671 hypothetical protein K22136 bshC; bacillithiol synthase C 99982 Energy metabolism D ShL2_00670 fdhD; formate dehydrogenase accessory protein K02379 fdhD; FdhD protein D ShL2_01312 fer; Ferredoxin-like protein K05337 fer; ferredoxin D ShL2_01894 iscU; SUF system FeS assembly protein K04488 iscU; nitrogen fixation protein NifU and related proteins D ShL2_01382 ATPase K04748 norQ; nitric oxide reductase NorQ protein D ShL2_02190 pyridine nucleotide-disulfide reductase K21739 rclA; probable pyridine nucleotide-disulfide oxidoreductase C 99983 Lipid metabolism D ShL2_01995 hypothetical protein K25232 fakB; fatty acid kinase fatty acid binding subunit D ShL2_01365 fatty acid-binding protein, DegV family K25232 fakB; fatty acid kinase fatty acid binding subunit C 99984 Nucleotide metabolism D ShL2_02014 nrdI; NrdI protein involved in ribonucleotide reductase function K03647 nrdI; protein involved in ribonucleotide reduction C 99985 Amino acid metabolism D ShL2_01659 alanine racemase K06997 yggS; PLP dependent protein C 99986 Glycan metabolism C 99987 Cofactor metabolism D ShL2_00679 mobB; molybdopterin-guanine dinucleotide biosynthesis protein B K03753 mobB; molybdopterin-guanine dinucleotide biosynthesis adapter protein D ShL2_00487 aminobenzoyl-glutamate transport protein K12942 abgT; aminobenzoyl-glutamate transport protein C 99988 Secondary metabolism C 99999 Others D ShL2_00449 Glyoxalase/bleomycin resistance protein/dioxygenase K15975 K15975; glyoxalase family protein D ShL2_00450 Glyoxalase/bleomycin resistance protein/dioxygenase K15975 K15975; glyoxalase family protein D ShL2_02278 DoxX family membrane protein K15977 K15977; putative oxidoreductase D ShL2_00451 phospholipase/carboxylesterase K06999 K06999; phospholipase/carboxylesterase D ShL2_01362 hypothetical protein K26958 brxA_B; bacilliredoxin D ShL2_01285 hypothetical protein K26958 brxA_B; bacilliredoxin D ShL2_02003 hypothetical protein K26959 brxC; monothiol bacilliredoxin B B 09192 Unclassified: genetic information processing C 99973 Transcription D ShL2_02191 cspC; cold-shock DNA-binding domain protein, CspC K03704 cspA; cold shock protein D ShL2_01389 cspA; cold-shock DNA-binding domain protein K03704 cspA; cold shock protein D ShL2_01822 spxA; transcriptional regulator Spx K16509 spxA; regulatory protein spx D ShL2_00858 tex; transcription accessory protein (S1 RNA binding) K06959 tex; protein Tex C 99974 Translation D ShL2_01857 S1 RNA-binding domain protein K07570 GSP13; general stress protein 13 D ShL2_02288 polyribonucleotide nucleotidyltransferase K07571 K07571; S1 RNA binding domain protein C 99975 Protein processing D ShL2_02272 cstR; modulator of heat shock repressor CtsR K19411 mcsA; protein arginine kinase activator D ShL2_01134 tig; trigger factor (prolyl isomerase) K03545 tig; trigger factor D ShL2_01957 smpB; tmRNA-binding protein K03664 smpB; SsrA-binding protein D ShL2_01821 mecA2; negative regulator of genetic competence K16511 mecA1_2; adapter protein MecA 1/2 C 99976 Replication and repair D ShL2_01149 radC; DNA repair protein RadC K03630 radC; DNA repair protein RadC D ShL2_02141 deoxyribonuclease K07457 K07457; endonuclease III related protein D ShL2_02308 GIY-YIG nuclease K07461 K07461; putative endonuclease D ShL2_01598 DNA recombination-mediator protein K04096 smf; DNA processing protein D ShL2_01342 dnaD; DNA replication protein, DnaD K02086 dnaD; DNA replication protein D ShL2_02350 bacteriophage terminase small subunit K07474 xtmA; phage terminase small subunit D ShL2_01939 bacteriophage terminase small subunit K07474 xtmA; phage terminase small subunit D ShL2_01906 small primase-like protein (Toprim domain) K07476 yusF; toprim domain protein D ShL2_01175 rarA; DNA-directed DNA polymerase III subunit gamma and tau K07478 ycaJ; putative ATPase D ShL2_00475 IS1181 transposase K07485 K07485; transposase D ShL2_00481 IS1181 transposase K07485 K07485; transposase D ShL2_00515 IS1181 transposase K07485 K07485; transposase D ShL2_02112 IS1181 transposase K07485 K07485; transposase D ShL2_00566 IS1181 transposase K07485 K07485; transposase D ShL2_01390 IS1181 transposase K07485 K07485; transposase D ShL2_02131 IS1181 transposase K07485 K07485; transposase D ShL2_00621 IS1181 transposase K07485 K07485; transposase D ShL2_02193 IS1181 transposase K07485 K07485; transposase D ShL2_00639 IS1181 transposase K07485 K07485; transposase D ShL2_00659 IS1181 transposase K07485 K07485; transposase D ShL2_02256 IS1181 transposase K07485 K07485; transposase D ShL2_00769 IS1181 transposase K07485 K07485; transposase D ShL2_00836 IS1181 transposase K07485 K07485; transposase D ShL2_02415 IS1181 transposase K07485 K07485; transposase D ShL2_00949 IS1181 transposase K07485 K07485; transposase D ShL2_00981 IS1181 transposase K07485 K07485; transposase D ShL2_01828 IS1181 transposase K07485 K07485; transposase D ShL2_01034 IS1181 transposase K07485 K07485; transposase D ShL2_01061 IS1181 transposase K07485 K07485; transposase D ShL2_01122 IS1181 transposase K07485 K07485; transposase D ShL2_01136 IS1181 transposase K07485 K07485; transposase D ShL2_00369 IS1181 transposase K07485 K07485; transposase D ShL2_02039 IS1181 transposase K07485 K07485; transposase D ShL2_00416 IS1181 transposase K07485 K07485; transposase D ShL2_01741 IS200-family transposase K07491 rayT; REP-associated tyrosine transposase D ShL2_02373 IS200-family transposase K07491 rayT; REP-associated tyrosine transposase D ShL2_02103 transposase for IS256 K07493 K07493; putative transposase D ShL2_02147 transposase for IS256 K07493 K07493; putative transposase D ShL2_02149 transposase for IS256 K07493 K07493; putative transposase D ShL2_01558 transposase for IS256 K07493 K07493; putative transposase D ShL2_01561 transposase for IS256 K07493 K07493; putative transposase D ShL2_02390 transposase for IS256 K07493 K07493; putative transposase D ShL2_00896 transposase for IS256 K07493 K07493; putative transposase D ShL2_00976 transposase for IS256 K07493 K07493; putative transposase D ShL2_01042 transposase for IS256 K07493 K07493; putative transposase D ShL2_01245 transposase for IS256 K07493 K07493; putative transposase D ShL2_02384 transposase K07497 K07497; putative transposase D ShL2_01824 transposase for IS431mec K07498 K07498; putative transposase D ShL2_01827 transposase for IS431mec K07498 K07498; putative transposase D ShL2_02161 transposase for IS431mec K07498 K07498; putative transposase D ShL2_02163 transposase for IS431mec K07498 K07498; putative transposase D ShL2_02169 transposase for IS431mec K07498 K07498; putative transposase D ShL2_02183 transposase for IS431mec K07498 K07498; putative transposase D ShL2_00028 transposase for IS431mec K07498 K07498; putative transposase D ShL2_00032 transposase for IS431mec K07498 K07498; putative transposase D ShL2_02410 transposase for IS431mec K07498 K07498; putative transposase D ShL2_00166 transposase for IS431mec K07498 K07498; putative transposase C 99979 Viral proteins C 99998 Others D ShL2_02318 Nucleoid-associated protein K09747 ebfC; nucleoid-associated protein EbfC B B 09193 Unclassified: signaling and cellular processes C 99977 Transport D ShL2_01451 APC family amino acid-polyamine-organocation transporter K03293 TC.AAT; amino acid transporter, AAT family D ShL2_00638 APC family amino acid-polyamine-organocation transporter K03293 TC.AAT; amino acid transporter, AAT family D ShL2_00363 APC family amino acid-polyamine-organocation transporter K03294 TC.APA; basic amino acid/polyamine antiporter, APA family D ShL2_00690 RND superfamily resistance-nodulation-cell division acriflavin:proton (H+) antiporter K03296 TC.HAE1; hydrophobic/amphiphilic exporter-1 (mainly G- bacteria), HAE1 family D ShL2_00328 citM; CitMHS family citrate-magnesium (Mg2+):proton (H+) citrate-calcium (Ca2+):proton (H+) symporter K03300 TC.CITMHS; citrate-Mg2+:H+ or citrate-Ca2+:H+ symporter, CitMHS family D ShL2_00332 cudT; choline/carnitine/betaine transporter, BCCT family K03451 TC.BCT; betaine/carnitine transporter, BCCT family D ShL2_02017 POT family proton (H+)-dependent oligopeptide transporter K03305 TC.POT; proton-dependent oligopeptide transporter, POT family D ShL2_02021 POT family proton (H+)-dependent oligopeptide transporter K03305 TC.POT; proton-dependent oligopeptide transporter, POT family D ShL2_02079 pitA; low-affinity inorganic phosphate transporter K03306 TC.PIT; inorganic phosphate transporter, PiT family D ShL2_00201 sodium/glucose cotransporter K03307 TC.SSS; solute:Na+ symporter, SSS family D ShL2_02337 Sodium-dependent transporter K03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family D ShL2_01429 amino acid carrier protein K03310 TC.AGCS; alanine or glycine:cation symporter, AGCS family D ShL2_00072 brnQ1; branched-chain amino acid transport system carrier protein K03311 TC.LIVCS; branched-chain amino acid:cation transporter, LIVCS family D ShL2_01384 brnQ_1; branched-chain amino acid permease, BrnQ_1 K03311 TC.LIVCS; branched-chain amino acid:cation transporter, LIVCS family D ShL2_00189 sodium:sulfate symporter family protein K03319 TC.DASS; divalent anion:Na+ symporter, DASS family D ShL2_02292 MOP superfamily PST family polysaccharide transporter K03328 TC.PST; polysaccharide transporter, PST family C 99978 Cell growth D ShL2_00527 scdA; cell division and morphogenesis-related protein K07322 ytfE; regulator of cell morphogenesis and NO signaling D ShL2_01193 ahs2; allophanate hydrolase subunit 2 K06350 kipA; antagonist of KipI D ShL2_01192 allophanate hydrolase subunit 1 K06351 kipI; inhibitor of KinA D ShL2_00904 SpoOM protein K06377 spo0M; sporulation-control protein D ShL2_02298 spoVG; septation protein spoVG K06412 spoVG; stage V sporulation protein G C 99993 Cell motility C 99995 Signaling proteins D ShL2_01714 typA; small GTP-binding protein domain:GTP-binding protein TypA K06207 typA; GTP-binding protein D ShL2_01227 phoH; phosphate starvation-inducible ATPase K06217 phoH; phosphate starvation-inducible protein PhoH and related proteins C 99992 Structural proteins D ShL2_02425 Glycosyl hydrolases family 25 K07273 acm; lysozyme D ShL2_00429 capA_2; Capsule biosynthesis protein CapA K07282 capA; gamma-polyglutamate biosynthesis protein CapA D ShL2_00428 capC; Capsule biosynthesis protein CapC K22116 capC; gamma-polyglutamate biosynthesis protein CapC D ShL2_02129 HlyD family secretion protein K02005 ABC.CD.TX; HlyD family secretion protein D ShL2_01139 hemX; hemA concentration negative effector hemX K02497 hemX; HemX protein D ShL2_00602 tcaA_1; teicoplanin resistance associated membrane protein TcaA protein K21463 tcaA; membrane-associated protein TcaA D ShL2_02441 tcaA_2; teicoplanin resistance associated membrane protein TcaA protein K21463 tcaA; membrane-associated protein TcaA C 99994 Others D ShL2_01405 phoU; phosphate uptake regulator K02039 phoU; phosphate transport system protein D ShL2_00287 hypothetical protein K26996 sdpI; immunity protein, SdpI family B B 09194 Poorly characterized C 99996 General function prediction only D ShL2_01820 coiA; competence protein CoiA K06198 coiA; competence protein CoiA D ShL2_01067 pheT2; phenylalanyl-tRNA synthetase (beta subunit) K06878 K06878; tRNA-binding protein D ShL2_01817 globin family protein K06886 glbN; hemoglobin D ShL2_00266 RND superfamily resistance-nodulation-cell division:proton (H+) antiporter K06994 K06994; putative drug exporter of the RND superfamily D ShL2_00081 Patatin-like phospholipase K07001 K07001; NTE family protein D ShL2_02341 Patatin-like phospholipase K07001 K07001; NTE family protein D ShL2_02136 haloacid dehalogenase-like hydrolase K07025 K07025; putative hydrolase of the HAD superfamily D ShL2_01673 5'-ribonucleotide phosphohydrolase K07025 K07025; putative hydrolase of the HAD superfamily D ShL2_00357 haloacid dehalogenase-like hydrolase K07025 K07025; putative hydrolase of the HAD superfamily D ShL2_01893 sufB; ABC superfamily ATP binding cassette transporter, membrane protein K09014 sufB; Fe-S cluster assembly protein SufB D ShL2_01896 sufD; ABC superfamily ATP binding cassette transporter, membrane protein K09015 sufD; Fe-S cluster assembly protein SufD D ShL2_00977 hypothetical protein K07038 K07038; inner membrane protein D ShL2_00762 membrane-bound metal-dependent hydrolase K07038 K07038; inner membrane protein D ShL2_00959 hypothetical protein K07058 K07058; membrane protein D ShL2_00217 rhodanese domain sulfurtransferase K07146 K07146; UPF0176 protein D ShL2_00401 3-demethylubiquinone-9 3-methyltransferase K04750 phnB; PhnB protein D ShL2_00859 hypothetical protein K03095 sprL; SprT-like protein D ShL2_00274 phage infection protein K01421 yhgE; putative membrane protein D ShL2_01898 integral membrane protein K08974 K08974; putative membrane protein D ShL2_01705 hypothetical protein K08976 K08976; putative membrane protein D ShL2_00848 membrane-flanked domain-containing protein K08981 K08981; putative membrane protein D ShL2_00516 yagU; Inner membrane protein YagU K08996 yagU; putative membrane protein C 99997 Function unknown D ShL2_02185 metal-dependent phosphohydrolase K06885 K06885; uncharacterized protein D ShL2_02077 Integral membrane protein interacts with FtsH-like protein K06890 K06890; uncharacterized protein D ShL2_02048 hypothetical protein K06934 K06934; uncharacterized protein D ShL2_02364 sodium/dicarboxylare symporter K06956 K06956; uncharacterized protein D ShL2_02262 YacP-like NYN domain protein K06962 K06962; uncharacterized protein D ShL2_01335 neutral zinc metallopeptidase K06973 K06973; uncharacterized protein D ShL2_00445 GNAT family acetyltransferase K06975 K06975; uncharacterized protein D ShL2_00381 Glyoxalase/bleomycin resistance protein/dioxygenase K07032 K07032; uncharacterized protein D ShL2_00060 toxin regulatorly-like protein K07035 K07035; uncharacterized protein D ShL2_00987 toxin regulatory protein K07035 K07035; uncharacterized protein D ShL2_00386 toxin regulatorly-like protein K07035 K07035; uncharacterized protein D ShL2_00154 hypothetical protein K07069 K07069; uncharacterized protein D ShL2_01972 NAD dependent epimerase/dehydratase familyprotein K07071 K07071; uncharacterized protein D ShL2_00137 KsdD-like steroid dehydrogenase K07077 K07077; uncharacterized protein D ShL2_00887 nitroreductase family protein K07078 K07078; uncharacterized protein D ShL2_01889 sulfite exporter TauE/SafE-like protein K07090 K07090; uncharacterized protein D ShL2_01096 sulfite exporter TauE/SafE-like protein K07090 K07090; uncharacterized protein D ShL2_00325 Sulfite exporter TauE/SafE K07090 K07090; uncharacterized protein D ShL2_01679 metallophosphoesterase K07095 K07095; uncharacterized protein D ShL2_00876 inner membrane protein K07112 K07112; uncharacterized protein D ShL2_00087 hypothetical protein K07118 K07118; uncharacterized protein D ShL2_01144 amoA; ammonia monooxygenase K07120 K07120; uncharacterized protein D ShL2_01299 short chain dehydrogenase K07124 K07124; uncharacterized protein D ShL2_01045 Fe-S oxidoreductase K07139 K07139; uncharacterized protein D ShL2_00121 hypothetical protein K07148 K07148; uncharacterized protein D ShL2_01019 yidD; membrane protein insertion efficiency factor K08998 K08998; uncharacterized protein D ShL2_02071 hypothetical protein K09145 K09145; uncharacterized protein D ShL2_00849 membrane-flanked domain-containing protein K09167 K09167; uncharacterized protein D ShL2_00847 bacterial membrane flanked domain protein K09167 K09167; uncharacterized protein D ShL2_00159 hypothetical protein K09384 K09384; uncharacterized protein D ShL2_02073 hypothetical protein K09705 K09705; uncharacterized protein D ShL2_01305 hypothetical protein K09763 K09763; uncharacterized protein D ShL2_02061 hypothetical protein K09768 K09768; uncharacterized protein D ShL2_00352 YciI-like protein K09780 K09780; uncharacterized protein D ShL2_01610 DNA-binding protein K09787 K09787; uncharacterized protein D ShL2_01736 ybaN; Inner membrane protein YbaN K09790 K09790; uncharacterized protein D ShL2_02068 hypothetical protein K09793 K09793; uncharacterized protein D ShL2_01400 hypothetical protein K00243 K00243; uncharacterized protein D ShL2_02345 hypothetical protein K09822 K09822; uncharacterized protein D ShL2_00656 hypothetical protein K09940 K09940; uncharacterized protein D ShL2_00117 hypothetical protein K09963 K09963; uncharacterized protein D ShL2_00643 hypothetical protein K09963 K09963; uncharacterized protein D ShL2_01441 hypothetical protein K09976 K09976; uncharacterized protein D ShL2_01157 hypothetical protein K07584 ysxB; uncharacterized protein D ShL2_02080 phosphate uptake regulator K07220 K07220; uncharacterized protein D ShL2_00979 hypothetical protein K07586 ygaC; uncharacterized protein D ShL2_01580 hypothetical protein K07742 ylxR; uncharacterized protein ! #
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: April 27, 2024