+C Peptidases and inhibitors KO #

  Peptidases and Inhibitors - Streptomyces avermitilis

% ! AAspartic peptidases B Family A1: pepsin family B Family A2: retropepsin family B Family A5: thermopsin family B Family A8: signal peptidase II family C SAVERM_6132 lspA; putative signal peptidase II K03101 lspA; signal peptidase II [EC:3.4.23.36] B Family A22: presenilin family B Family A24: type IV prepilin peptidase family C SAVERM_4824 pilD; putative leader peptidase (prepilin peptidase) / N-methyltransferase K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] B Family A25: gpr protease family B Family A26: omptin family B Family A28 B Family A31: HybD endopeptidase family C SAVERM_7372 hupD; putative [NiFe] hydrogenase-specific C-terminal protease K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-] B Family A36 # ACysteine peptidases B Family C1: papain family B Family C2: calpain family B Family C3: picornain family B Family C4: NIa protease family B Family C5 B Family C9 B Family C10: streptopain family B Family C11: clostripain family B Family C12: ubiquitin C-terminal hydrolase family B Family C13: legumain family B Family C14: caspase family B Family C15: pyroglutamyl peptidase I family B Family C16 B Family C19: ubiquitin-specific protease family B Family C25: gingipain family B Family C26: gamma-glutamyl hydrolase family C SAVERM_3479 guaA; putative GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] C SAVERM_6723 putative secreted protein K07010 K07010; putative glutamine amidotransferase B Family C27 B Family C30 B Family C37 B Family C39 B Family C40 C SAVERM_6062 putative NLP/P60-family secreted protein (PgpA peptidase) K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] C SAVERM_3464 putative NLP/P60-family secreted protein (PgpA peptidase) K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] C SAVERM_2957 putative NLP/P60-family secreted protein (PgpA peptidase) K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] C SAVERM_6063 putative NLP/P60-family secreted protein (PgpA peptidase) K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] B Family C44 C SAVERM_4135 purF; putative phosphoribosylpyrophosphate amidotransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C SAVERM_6189 gltB; putative glutamate synthase(NADPH) large subunit K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] C SAVERM_4963 glmS1; putative L-glutamine-D-fructose-6-phosphate amidotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] C SAVERM_5265 glmS2; putative L-glutamine-D-fructose-6-phosphate amidotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] C SAVERM_5689 mcjC2; putative asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] C SAVERM_259 mcjC1; putative asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] C SAVERM_2197 hypothetical protein K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] B Family C45 B Family C46: hedgehog family B Family C47: staphopain family B Family C48: Ulp1 endopeptidase family B Family C50: separase family B Family C54: Aut2 peptidase family B Family C55: YopJ protease family B Family C56: PfpI endopeptidase family C SAVERM_7231 pfpI2; putative intracellular protease/amidase K05520 yhbO; deglycase [EC:3.5.1.124] C SAVERM_1876 pfpI1; putative intracellular protease/amidase K05520 yhbO; deglycase [EC:3.5.1.124] B Family C57: vaccinia virus I7 peptidase family B Family C58 B Family C59 B Family C60 C SAVERM_4336 hypothetical protein K07284 srtA; sortase A [EC:3.4.22.70] C SAVERM_4333 putative secreted protein K07284 srtA; sortase A [EC:3.4.22.70] B Family C63 B Family C64 B Family C65 B Family C67 B Family C69 B Family C70 B Family C75 B Family C76 B Family C78 B Family C79 B Family C82 B Family C83 B Family C85 B Family C86 B Family C88 B Family C89 B Family C97 B Family C98 B Family C110 # AGlutamic peptidases B Family G1 B Family G4 B Family G5: prenyl protease 2 family # AMetallo peptidases B Family M1 C SAVERM_6212 pepN3; putative aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2] C SAVERM_5395 pepN2; putative aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2] C SAVERM_5411 pepG; putative aminopeptidase G K01256 pepN; aminopeptidase N [EC:3.4.11.2] B Family M2 B Family M3 B Family M4: thermolysin family B Family M5: mycolysin family B Family M6: immune inhibitor A family C SAVERM_5155 putative protease, secreted K09607 ina; immune inhibitor A [EC:3.4.24.-] B Family M7: snapalysin family C SAVERM_4407 putative snapalysin (secreted metalloprotease) K01416 snpA; snapalysin [EC:3.4.24.77] C SAVERM_2939 putative snapalysin (secreted metalloprotease) K01416 snpA; snapalysin [EC:3.4.24.77] B Family M8: leishmanolysin family B Family M9 B Family M10 B Family M12: astacin/adamalysin family B Family M13: neprilysin family B Family M14: carboxypeptidase A family C SAVERM_3266 putative carboxypeptidase T (secreted zinc-binding carboxypeptidase) K05996 cpt; carboxypeptidase T [EC:3.4.17.18] B Family M15: zinc D-Ala-D-Ala carboxypeptidase family C SAVERM_1809 putative dipeptidase K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22] B Family M16: pitrilysin family B Family M17: leucyl aminopeptidase family C SAVERM_6025 pepA; putative leucyl aminopeptidase (cytosol aminopeptidase) K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] B Family M18 B Family M19: membrane dipeptidase family C SAVERM_5023 putative dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19] B Family M20 C SAVERM_3125 dapE; putative succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] C SAVERM_1471 putative peptidase K23980 tpdA; cysteinylglycine-S-conjugate dipeptidase [EC:3.4.13.23] B Family M23 B Family M24 C SAVERM_4948 map3; putative methionyl aminopeptidase, secreted K01265 map; methionyl aminopeptidase [EC:3.4.11.18] C SAVERM_5931 map4; putative methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18] C SAVERM_1956 map1; putative methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18] C SAVERM_1974 map2; putative methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18] C SAVERM_4230 pepP; putative Xaa-Pro aminopeptidase aminopeptidase P) K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] B Family M26 B Family M27 B Family M28: aminopeptidase Y family C SAVERM_4872 lap; putative leucyl aminopeptidase, secreted (aminopeptidase S) K19702 E3.4.11.24; aminopeptidase S [EC:3.4.11.24] B Family M29: aminopeptidase T family B Family M32: carboxypeptidase Taq family B Family M34: anthrax lethal factor family B Family M35: deuterolysin family B Family M36: fungalysin family B Family M38: beta-aspartyl dipeptidase family B Family M41: FtsH endopeptidase family C SAVERM_4666 ftsH; putative cell division protein FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] B Family M42: glutamyl aminopeptidase family B Family M43: cytophagalysin family B Family M44 B Family M48: Ste24 endopeptidase family C SAVERM_6003 htpX2; putative heat shock protein, protease K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] C SAVERM_4891 htpX1; putative heat shock protein, protease K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] B Family M49: dipeptidyl-peptidase III family B Family M50: S2P protease family C SAVERM_1106 putative subfamily M50B peptidases K16922 yydH; putative peptide zinc metalloprotease protein B Family M54 B Family M55: DppA aminopeptidase family C SAVERM_1111 dppA1; putative D-aminopeptidase (family M55 peptidases) K16203 dppA1; D-amino peptidase [EC:3.4.11.-] C SAVERM_1900 dppA2; putative D-aminopeptidase K16203 dppA1; D-amino peptidase [EC:3.4.11.-] B Family M56 C SAVERM_1500 putative integral membrane protein K02172 blaR1; bla regulator protein blaR1 B Family M67 B Family M72 B Family M73 B Family M74 B Family M80 B Family M82 C SAVERM_4116 putative membrane protein K24131 prsW; protease PrsW [EC:3.4.-.-] B Family M85 B Family M88 B Family M90 # AAsparagine peptide lyases B Family N1 B Family N8 # AMixed peptidases B Family P1: DmpA aminopeptidase family B Family P2 # ASerine peptidases B Family S1: chymotrypsin family C SAVERM_3115 pepD1; putative serine protease K08372 pepD; putative serine protease PepD [EC:3.4.21.-] C SAVERM_4223 pepD3; putative serine protease, secreted K08372 pepD; putative serine protease PepD [EC:3.4.21.-] C SAVERM_4045 putative Htra2 peptidase K08372 pepD; putative serine protease PepD [EC:3.4.21.-] C SAVERM_6552 sprA; putative serine protease precursor K18545 sprB; streptogrisin B [EC:3.4.21.81] C SAVERM_1000 sprC; putative streptogrisin C (secreted serine protease) K18546 sprC; streptogrisin C [EC:3.4.21.-] C SAVERM_6553 sprD1; putative streptogrisin D (secreted serine protease) K18547 sprD; streptogrisin D [EC:3.4.21.-] C SAVERM_7497 sprD2; putative streptogrisin D (secreted serine protease) K18547 sprD; streptogrisin D [EC:3.4.21.-] B Family S3: togavirin family B Family S6 B Family S7: flavivirin family B Family S8: subtilisin family C SAVERM_2540 putative mycosin-1 (secreted serine protease) K14743 mycP; membrane-anchored mycosin MYCP [EC:3.4.21.-] B Family S9: prolyl oligopeptidase family C SAVERM_3144 putative peptidase K01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5] B Family S10 B Family S11: D-Ala-D-Ala carboxypeptidase A family C SAVERM_1311 dacA; putative D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] C SAVERM_3413 dacB; putative D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] C SAVERM_5913 dacF; putative D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] C SAVERM_4379 dacD; putative D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] C SAVERM_3781 dacC; putative D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] B Family S12: D-Ala-D-Ala carboxypeptidase B family B Family S13: D-Ala-D-Ala peptidase C family C SAVERM_4662 dacE; putative D-alanyl-D-alanine carboxypeptidase K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] B Family S14: ClpP endopeptidase family C SAVERM_1146 clpP4; putative ATP-dependent Clp protease proteolytic subunit 1 K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] C SAVERM_1147 clpP5; putative ATP-dependent Clp protease proteolytic subunit 2 K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] C SAVERM_7101 clpP3; putative ATP-dependent Clp protease proteolytic subunit 2 K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] C SAVERM_5447 clpP1; putative ATP-dependent Clp protease proteolytic subunit 1 K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] C SAVERM_5448 clpP2; putative ATP-dependent Clp protease proteolytic subunit 2 K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] B Family S15 B Family S16: lon protease family C SAVERM_2966 lonA; putative lon class III heat-shock ATP-dependent protease K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53] C SAVERM_3057 putative secreted protein K07177 K07177; Lon-like protease C SAVERM_5142 sdrC; putative secreted protein K07177 K07177; Lon-like protease B Family S21: assemblin family B Family S24: LexA family C SAVERM_2463 lexA; putative SOS regulatory protein LexA K01356 lexA; repressor LexA [EC:3.4.21.88] B Family S26: signal peptidase I family C SAVERM_2636 lepB1; putative signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] C SAVERM_2637 lepB2; putative signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] C SAVERM_2638 lepB3; putative signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] C SAVERM_2639 lepB4; putative signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] B Family S28 B Family S31 B Family S32 B Family S33 C SAVERM_875 pip; putative proline iminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5] C SAVERM_141 ephA1; putative epoxide hydrolase K27108 ephA_B; epoxide hydrolase A/B [EC:3.3.2.-] C SAVERM_2105 ephB; putative epoxide hydrolase K27108 ephA_B; epoxide hydrolase A/B [EC:3.3.2.-] C SAVERM_3810 ephA2; putative epoxide hydrolase K27108 ephA_B; epoxide hydrolase A/B [EC:3.3.2.-] B Family S41: C-terminal processing peptidase family C SAVERM_5106 putative carboxy-terminal processing protease precursor, secreted K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] C SAVERM_5574 pepD4; putative tricorn core peptidase K08676 tri; tricorn protease [EC:3.4.21.-] C SAVERM_3620 pepD2; putative tricorn core peptidase K08676 tri; tricorn protease [EC:3.4.21.-] B Family S45 C SAVERM_3675 pacB1; putative penicillin acylase, secreted K01434 pac; penicillin G amidase [EC:3.5.1.11] C SAVERM_4171 pacB2; putative penicillin acylase K01434 pac; penicillin G amidase [EC:3.5.1.11] B Family S49: protease IV family B Family S50 B Family S51 B Family S53 B Family S54: Rhomboid family C SAVERM_2227 hypothetical protein K07059 K07059; rhomboid family protein C SAVERM_6059 putative integral membrane protein K07059 K07059; rhomboid family protein B Family S55: SpoIVB peptidase family B Family S62 B Family S66 C SAVERM_1897 putative LD-carboxypeptidase (murein tetrapeptidase) K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13] B Family S77: phage prohead processing peptidase family B Family S78 # AThreonine peptidases B Family T1: proteasome family C SAVERM_6682 prcA; putative 20S proteasome alpha-subunit K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] C SAVERM_6681 prcB1; putative 20S proteasome beta-subunit K03433 psmB; proteasome beta subunit [EC:3.4.25.1] C SAVERM_2812 prcB2; putative 20S proteasome beta-subunit K03433 psmB; proteasome beta subunit [EC:3.4.25.1] B Family T2 B Family T3: gamma-glutamyltransferase family C SAVERM_1938 ggt1; putative gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] C SAVERM_1957 ggt2; putative gamma-glutamyltranspeptidase, secreted K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] # APeptidases of unknown catalytic type B Family U32 B Family U62 C SAVERM_6461 tldD; putative modulator of DNA gyrase K03568 tldD; TldD protein # APeptidase inhibitors B Family I1: Kazal family B Family I2: Kunitz - BPTI family B Family I4: serpin family B Family I11: ecotin family B Family I17: WAP-type family B Family I25: cystatin family B Family I27: calpastatin family B Family I32: IAP family B Family I34: IA3 family B Family I35: timp family B Family I39: alpha2M family B Family I47: latexin family B Family I49: proSAAS family B Family I51: IC family B Family I57: staphostatin B family B Family I63 B Family I80 B Family I87 B Family I93 ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 13, 2023 #
Classification taken and modified from MEROPS