+D
#
Transporters - Streptococcus pyogenes Manfredo (serotype M5)
%
!
AABC transporters, eukaryotic type
B ABCA (ABC1) subfamily
C ABCA1, 2, 3, 4, 7, 12, 13 subgroups
C ABCA5, 6, 8, 9, 10 subgroups
B ABCB (MDR/TAP) subfamily
C ABCB2, 3, 8, 9, 10 subgroups
C ABCB1, 4, 5 subgroups
C ABCB6, 7 subgroups
C ABCB11 subgroup
C ABCB-BAC subgroup
D SpyM50175 ABC transporter ATP-binding membrane protein K18891 patA; ATP-binding cassette, subfamily B, multidrug efflux pump
D SpyM50176 ABC transporter ATP-binding membrane protein K18892 patB; ATP-binding cassette, subfamily B, multidrug efflux pump
D SpyM50920 ABC transporter ATP-binding membrane protein K18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump
D SpyM50919 ABC transporter ATP-binding membrane protein K18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump
B ABCC (CFTR/MRP) subfamily
C ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
C ABCC7 subgroup
C ABCC8, 9 subgroups
C ABCC-BAC subgroup
D SpyM50321 ABC transporter ATP-binding membrane protein K06148 ABCC-BAC; ATP-binding cassette, subfamily C, bacterial
D SpyM50322 ABC transporter ATP-binding membrane protein K06148 ABCC-BAC; ATP-binding cassette, subfamily C, bacterial
B ABCD (ALD) subfamily
C ABCD1 subgroup
C ABCD2 subgroup
C ABCD3 subgroup
C ABCD4 subgroup
C Others
B ABCG (White) subfamily
C ABCG1, 4 subgroups
C ABCG2, 3 subgroups
C ABCG5, 8 subgroups
B Other subfamilies
C Macrolide exporter
C Other ABC transporters
D SpyM51133 ABC transporter ATP-binding protein K15738 uup; ABC transport system ATP-binding/permease protein
#
AABC transporters, prokaryotic type
B Mineral and organic ion transporters
C Sulfate/thiosulfate transporter
C Molybdate transporter
C Molybdate/tungstate transporter
C Tungstate transporter
C Nitrate/nitrite transporter
C Bicarbonate transporter
C Taurine transporter
C Sulfonate transporter
C Phthalate transporter
C Iron(III) transporter
D SpyM50980 extracellular solute-binding protein K02012 afuA; iron(III) transport system substrate-binding protein
C Thiamine transporter
C Spermidine/putrescine transporter
D SpyM50959 potD; spermidine/putrescine extracellular binding protein K11069 potD; spermidine/putrescine transport system substrate-binding protein
D SpyM50960 potC; spermidine/putrescine ABC transporter permease protein K11070 potC; spermidine/putrescine transport system permease protein
D SpyM50961 potB; putative spermidine/putrescine ABC transporter permease protein K11071 potB; spermidine/putrescine transport system permease protein
D SpyM50962 potA; putative spermidine/putrescine ABC transporter ATP-binding protein K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11]
C Putrescine transporter
C Putative spermidine/putrescine transporter
C Mannopine transporter
C 2-Aminoethylphosphonate transporter
C Glycine betaine/proline transporter
D SpyM50151 putative glycine-betaine binding permease protein K02001 proW; glycine betaine/proline transport system permease protein
D SpyM50150 putative glycine betaine transport ATP-binding protein K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9]
C Osmoprotectant transporter
D SpyM50934 ABC-type glycine betaine transport system protein K05845 opuC; osmoprotectant transport system substrate-binding protein
D SpyM50935 ABC-type glycine betaine transport system ATP-binding protein K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9]
C Riboflavin transporter
C Putative hydroxymethylpyrimidine transporter
C Putative thiamine transporter
C Putative thiamine transporter
C NitT/TauT family transporter
B Saccharide, polyol, and lipid transporters
C Maltose/maltodextrin transporter
D SpyM51653 msmK; multiple sugar-binding transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Maltose transporter
D SpyM51653 msmK; multiple sugar-binding transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Arabinogalactan oligomer/maltooligosaccharide transport system
D SpyM50802 malX; putative maltose/maltodextrin-binding protein precursor K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein
D SpyM50801 malC; putative maltose/maltodextrin ABC transport system permease protein K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D SpyM50800 malD; putative maltose/maltodextrin ABC transport system permease protein K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D SpyM51653 msmK; multiple sugar-binding transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Raffinose/stachyose/melibiose transporter
D SpyM51653 msmK; multiple sugar-binding transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Alpha-glucoside transporter
D SpyM51653 msmK; multiple sugar-binding transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Glucose/arabinose transporter
C Glucose/mannose transporter
D SpyM51653 msmK; multiple sugar-binding transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Trehalose/maltose transporter
D SpyM51653 msmK; multiple sugar-binding transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Trehalose transporter
C N-Acetylglucosamine transporter
C Cellobiose transporter
D SpyM51653 msmK; multiple sugar-binding transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C N,N'-Diacetylchitobiose transporter
D SpyM51653 msmK; multiple sugar-binding transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Putative chitobiose transporter
C L-Arabinose transporter
C Lactose/L-arabinose transporter
C L-Arabinose/D-xylose transporter
D SpyM51653 msmK; multiple sugar-binding transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Oligogalacturonide transporter
C Alpha-1,4-digalacturonate transporter
C Putative aldouronate transporter
D SpyM50547 extracellular solute-binding protein K17318 lplA; putative aldouronate transport system substrate-binding protein
D SpyM50545 binding-protein-dependent transport system membrane protein K17319 lplB; putative aldouronate transport system permease protein
D SpyM50546 binding-protein-dependent transport system membrane protein K17320 lplC; putative aldouronate transport system permease protein
C Alpha-galactoside transporter
C Methyl-galactoside transporter
C D-Galactose transporter
C D-Xylose transporter
C Xylobiose transporter
C Fucose transporter
C Sugar transporter
C Multiple sugar transporter
C D-Allose transporter
C Fructose transporter
C Rhamnose transporter
C Ribose transporter
C Galactofuranose transporter
C Erythritol transporter
C Putative xylitol transporter
C Inositol transporter
C Inositol transporter
C Inositol-phosphate transporter
C Fructooligosaccharide transporter
D SpyM51653 msmK; multiple sugar-binding transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Fructooligosaccharide transporter
D SpyM51653 msmK; multiple sugar-binding transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Glycerol transporter
C Putative sn-Glycerol 3-phosphate transporter
C Putative sorbitol/mannitol transporter
D SpyM51653 msmK; multiple sugar-binding transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Arabinooligosaccharide transporter
D SpyM51653 msmK; multiple sugar-binding transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Arabinooligosaccharide transporter
C Polygalacturonan/rhamnogalacturonan transporter
D SpyM51653 msmK; multiple sugar-binding transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Pectin-derived oligosaccharide transporter
D SpyM51653 msmK; multiple sugar-binding transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C General nucleoside transporter
D SpyM50132 basic lipoprotein K07335 bmpA; basic membrane protein A and related proteins
D SpyM50856 putative lipoprotein K07335 bmpA; basic membrane protein A and related proteins
D SpyM50858 ABC transporter permease protein K23535 nupB; general nucleoside transport system permease protein
D SpyM50859 ABC transporter permease protein K23536 nupC; general nucleoside transport system permease protein
D SpyM50857 ABC transporter ATP-binding protein K23537 nupA; general nucleoside transport system ATP-binding protein
C Riboflavin transporter
C UDP-glucose/iron transporter
C AI-2 transporter
C gamma-Hexachlorocyclohexane transporter
C Phospholipid transporter
C Mce system transporter
C Putative multiple sugar transporter
D SpyM50192 extracellular solute-binding lipoprotein K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein
D SpyM50193 putative transport system permease K02025 ABC.MS.P; multiple sugar transport system permease protein
D SpyM50194 putative transport system permease K02026 ABC.MS.P1; multiple sugar transport system permease protein
D SpyM51653 msmK; multiple sugar-binding transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Putative simple sugar transporter
B Phosphate and amino acid transporters
C Phosphate transporter
D SpyM50843 pstS; putative phosphate ABC transporter,extracellular phosphate-binding lipoprotein K02040 pstS; phosphate transport system substrate-binding protein
D SpyM50844 pstC; putative phosphate ABC transporter permease protein K02037 pstC; phosphate transport system permease protein
D SpyM50845 putative phosphate ABC transporter permease protein K02038 pstA; phosphate transport system permease protein
D SpyM50847 pstB1; phosphate import ATP-binding protein 1 K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D SpyM50846 pstB2; phosphate import ATP-binding protein 2 K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
C Phosphonate transporter
C Lysine/arginine/ornithine transporter
C Histidine transporter
C Glutamine transporter
D SpyM50789 putative glutamine ABC transporter,glutamine-binding protein/permease protein K10036 glnH; glutamine transport system substrate-binding protein
D SpyM50788 glnQ1; putative glutamine ABC transporter, ATP-binding protein 1 K10038 glnQ; glutamine transport system ATP-binding protein [EC:7.4.2.1]
C Arginine transporter
C Glutamate/aspartate transporter
C Aspartate/glutamate/glutamine transporter
C Octopine/nopaline transporter
C General L-amino acid transporter
C Glutamate transporter
C Cystine transporter
D SpyM51102 extracellular solute-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein
D SpyM51585 extracellular solute-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein
D SpyM51101 transport system membrane protein K10009 tcyB; L-cystine transport system permease protein
D SpyM50428 ABC transporter permease protein K10009 tcyB; L-cystine transport system permease protein
D SpyM50429 ABC transporter ATP-binding protein K10010 tcyC; L-cystine transport system ATP-binding protein [EC:7.4.2.1]
C L-Cystine transporter
C Arginine/ornithine transporter
C Arginine/lysine/histidine/glutamine transporter
C Arginine/lysine/histidine transporter
D SpyM51211 extracellular solute-binding protein K23059 artP; arginine/lysine/histidine transporter system substrate-binding protein
D SpyM50614 putative amino acid ABC transporter permease protein K17077 artQ; arginine/lysine/histidine transport system permease protein
D SpyM50615 glnQ3; putative glutamine transporter, ATP-binding protein 3 K23060 artR; arginine/lysine/histidine transport system ATP-binding protein [EC:7.4.2.1]
C Hydroxyproline transporter
C Branched-chain amino acid transporter
C Neutral amino acid transporter
C D-Methionine transporter
D SpyM51584 putative lipoprotein K02073 metQ; D-methionine transport system substrate-binding protein
D SpyM51582 putative D-methionine transport system permease protein K02072 metI; D-methionine transport system permease protein
D SpyM51583 putative D-methionine transport system ATP-binding protein K02071 metN; D-methionine transport system ATP-binding protein
C Urea transporter
C Putative tryptophan/tyrosine transporter
D SpyM51016 putative exported protein K01989 K01989; putative tryptophan/tyrosine transport system substrate-binding protein
D SpyM51014 ABC transporter permease protein K05832 K05832; putative tryptophan/tyrosine transport system permease protein
D SpyM51013 ABC transporter ATP-binding protein K05833 K05833; putative tryptophan/tyrosine transport system ATP-binding protein
C Putative lysine transporter
D SpyM50215 glutamine ABC transporter, glutamine-binding protein/permease protein K17073 lysX1; putative lysine transport system substrate-binding protein
D SpyM50214 glnQ2; putative glutamine ABC transporter, ATP-binding protein 2 K17076 lysY; putative lysine transport system ATP-binding protein
C Putative lysine/arginine/ornithine/histidine/octopine transporter
C Putative S-methylcysteine transporter
C Putative polar amino acid transporter
D SpyM50819 putative amino acid ABC transporter,extracellular amino acid-binding protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D SpyM50817 putative amino acid ABC transporter permease protein K02029 ABC.PA.P; polar amino acid transport system permease protein
D SpyM50818 putative amino acid ABC transporter ATP-binding protein K02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1]
B Peptide and nickel transporters
C Oligopeptide transporter
D SpyM50227 putative extracellular oligopeptide-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein
D SpyM50228 putative oligopeptide transporter permease protein K15581 oppB; oligopeptide transport system permease protein
D SpyM50229 putative oligopeptide transporter permease protein K15582 oppC; oligopeptide transport system permease protein
D SpyM50230 putative oligopeptide transporter ATP-binding protein K15583 oppD; oligopeptide transport system ATP-binding protein
D SpyM50231 putative oligopeptide transporter ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein
C Dipeptide transporter
C Dipeptide transporter
C Cationic peptide transporter
C Nickel transporter
C Nickel transporter
C Glutathione transporter
C Peptides/nickel transporter
D SpyM51673 dppA; dipeptide-binding extracellular protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D SpyM51674 dppB; dipeptide transport system permease protein DppB K02033 ABC.PE.P; peptide/nickel transport system permease protein
D SpyM51675 dppC; dipeptide transport system permease protein DppC K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D SpyM51676 dppD; dipeptide transport system ATP-binding protein DppD K02031 ddpD; peptide/nickel transport system ATP-binding protein
D SpyM51677 dppE; dipeptide transport system ATP-binding protein DppF K02032 ddpF; peptide/nickel transport system ATP-binding protein
C Microcin C transporter
B Metallic cation, iron-siderophore and vitamin B12 transporters
C Ferric citrate transporter
C Ferric hydroxamate transporter
C Ferric hydroxamate/heme transporter
D SpyM51535 fhuD; putative ferrichrome-binding protein precursor K25308 fhuD; ferric hydroxamate/heme transport system substrate-binding protein
D SpyM51536 fhuB; ferrichrome transport permease K25288 fhuB; ferric hydroxamate/heme transport system permease protein
D SpyM51537 fhuG; ferrichrome transport permease K25289 fhuG; ferric hydroxamate/heme transport system permease protein
D SpyM51534 fhuC; ferrichrome transport ATP-binding protein K25290 fhuA; ferric hydroxamate/heme transport system ATP-binding protein [EC:7.2.2.16]
C Heme transporter
C Heme transporter
D SpyM50318 putative transport system extracellular binding lipoprotein K25113 htsA; heme transport system substrate-binding protein
D SpyM50319 putative iron/heme permease K25114 htsB; heme transport system permease protein
D SpyM50320 ABC transporter ATP-binding protein K25115 htsC; heme transport system ATP-binding protein [EC:7.6.2.5]
D SpyM50317 putative membrane protein K25119 shp; heme transport system cell surface heme-binding protein
D SpyM50316 putative iron transport-associated protein K25120 shr; heme sequestration protein
C Iron-siderophore transporter
C Iron-siderophore transporter
C Iron-siderophore transporter
C Iron complex transporter
C Vitamin B12 transporter
C Cobalamin transporter
C Manganese transporter
C Manganese transporter
C Zinc transporter
D SpyM51680 lmb; laminin binding protein K09815 znuA; zinc transport system substrate-binding protein
D SpyM51261 adcA; zinc-binding protein AdcA precursor K09815 znuA; zinc transport system substrate-binding protein
D SpyM50077 ABC transporter permease protein K09816 znuB; zinc transport system permease protein
D SpyM50076 ABC transporter ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
C Iron/zinc/manganese/copper transporter
D SpyM51497 mtsA; metal ABC transporter substrate-binding lipoprotein precursor K11704 mtsA; iron/zinc/manganese/copper transport system substrate-binding protein
D SpyM51495 mtsC; metal cation ABC transporter membrane protein K11705 mtsC; iron/zinc/manganese/copper transport system permease protein
D SpyM51496 mtsB; metal cation ABC transporter ATP-binding protein K11706 mtsB; iron/zinc/manganese/copper transport system ATP-binding protein
C Manganese/iron transporter
C Manganese/zinc transporter
C Manganese/zinc/iron transporter
C Manganese/iron transporter
C Cobalt transporter
C Nickel transporter
C Biotin transporter
D SpyM50159 BioY family protein K03523 bioY; biotin transport system substrate-specific component
C Energy-coupling factor transporter
D SpyM50159 BioY family protein K03523 bioY; biotin transport system substrate-specific component
D SpyM50323 putative membrane protein K16926 htsT; energy-coupling factor transport system substrate-specific component
D SpyM51362 putative membrane protein K16927 cbrT; energy-coupling factor transport system substrate-specific component
D SpyM51816 putative cobalt transport protein K16785 ecfT; energy-coupling factor transport system permease protein
D SpyM50324 putative membrane protein K16785 ecfT; energy-coupling factor transport system permease protein
D SpyM51818 ABC transporter ATP-binding protein K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D SpyM51817 ABC transporter ATP-binding protein K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D SpyM50325 ABC transporter ATP-binding protein K01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
C Putative zinc/manganese transporter
B ABC-2 type and other transporters
C Multidrug/hemolysin transporter
C Capsular polysaccharide transporter
C Vi polysaccharide transporter
C Homopolymeric O-antigen
C Lipopolysaccharide transporter
C Teichoic acid transporter
C Lipooligosaccharide transporter
C Sodium transporter
C Lantibiotic transporter
C Lantibiotic transporter
C Copper-processing transporter
C Gliding motility-associated transporter
C Putative peptide transporter
C Hemin transporter
C Daunorubicin/doxorubicin transporter
C Oleandomycin transporter
C Pyoluteorin transporter
C Drug efflux transporter
C Linearmycin/streptolysin S transporer
D SpyM51239 sagI; ABC-2 type transporter protein K25142 lnrN; linearmycin/streptolysin S transport system permease protein
D SpyM51240 sagH; ABC-2 type transporter protein K25143 lnrM; linearmycin/streptolysin S transport system permease protein
D SpyM51241 sagG; ABC transporter ATP-binding protein K25144 lnrL; linearmycin/streptolysin S transport system ATP-binding protein
C Bacitracin transporter
C Bacitracin transporter
C Bacitracin transporter
C Beta-exotoxin I transporter
C Polyether ionophore transporter
C Uncharacterized ABC transporter
C Cationic antimicrobial peptide transporter
C Fluoroquinolones transporter
C Lipoprotein-releasing transporter
C Acetoin utilization transporter
C Antimicrobial peptide resistance transporter
D SpyM51161 putative permease K24948 yknZ; antimicrobial peptide resistance transport system permease protein
D SpyM51689 putative permease protein K24948 yknZ; antimicrobial peptide resistance transport system permease protein
D SpyM51690 ABC transporter ATP-binding protein K24949 yknY; antimicrobial peptide resistance transport system ATP-binding protein [EC:7.6.2.-]
D SpyM51162 ABC transporter ATP-binding protein K24949 yknY; antimicrobial peptide resistance transport system ATP-binding protein [EC:7.6.2.-]
C Heterocyst specific transporter
C Heme transporter
C Cell division transporter
D SpyM51331 ftsX; putative cell division protein K09811 ftsX; cell division transport system permease protein
D SpyM51332 ftsE; putative cell division ATP-binding protein K09812 ftsE; cell division transport system ATP-binding protein
C Viologen exporter family transporter
D SpyM51440 putative membrane protein K25154 evrC; viologen exporter family transport system permease protein
D SpyM51441 putative membrane protein K25155 evrB; viologen exporter family transport system permease protein
D SpyM51442 ABC transporter ATP-binding protein K25156 evrA; viologen exporter family transport system ATP-binding protein
C ABC-2 type transporter
D SpyM50375 ABC transporter protein EcsB K25157 ecsB; ABC-2 type transport system permease protein
D SpyM50374 ABC transporter ATP-binding protein K25158 ecsA; ABC-2 type transport system ATP-binding protein
C ABC-2 type transporter
D SpyM50328 putative membrane protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D SpyM51201 putative polysaccharide export ABC transporter permease protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D SpyM50418 putative membrane protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D SpyM50809 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SpyM50417 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SpyM51200 putative polysaccharide export system ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SpyM50327 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
C Putative ABC transporter
D SpyM51603 salY; putative salivaricin A transporter permease protein K02004 ABC.CD.P; putative ABC transport system permease protein
D SpyM51216 putative permease K02004 ABC.CD.P; putative ABC transport system permease protein
D SpyM50833 ABC transporter permease protein K02004 ABC.CD.P; putative ABC transport system permease protein
D SpyM51604 salX; putative salivaricin A transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D SpyM50832 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D SpyM51215 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
C Orphan ABC ATPase
D SpyM50220 sufC; putative ABC transporter, ATP-binding protein K09013 sufC; Fe-S cluster assembly ATP-binding protein
#
ASolute carrier family (SLC)
B SLC1: High-affinity glutamate and neutral amino acid transporter
B SLC2: Facilitative GLUT transporter
B SLC3: Heavy subunits of the heteromeric amino acid transporters
B SLC4: Bicarbonate transporter
B SLC5: Sodium glucose cotransporter
B SLC6: Sodium- and chloride-dependent neurotransmitter transporter
B SLC7: Cationic amino acid transporter/glycoprotein-associated
B SLC8: Na+/Ca2+ exchanger
B SLC9: Na+/H+ exchanger
B SLC10: Sodium bile salt cotransporter
B SLC11: Proton-coupled metal ion transporter
B SLC12: Electroneutral cation-coupled Cl cotransporter
B SLC13: Human Na+-sulfate/carboxylate cotransporter
B SLC14: Urea transporter
B SLC15: Proton oligopeptide cotransporter
B SLC16: Monocarboxylate transporter
B SLC17: Vesicular glutamate transporter
B SLC18: Vesicular amine transporter
B SLC19: Folate/thiamine transporter
B SLC20: Type III Na+-phosphate cotransporter
B SLC21/ASLCO: Organic anion transporter
B SLC22: Organic cation/anion/zwitterion transporter
B SLC23: Na+-dependent ascorbic acid transporter
B SLC24: Na+/(Ca2+-K+) exchanger
B SLC25: Mitochondrial carrier
B SLC26: Multifunctional anion exchanger
B SLC27: Fatty acid transporter
B SLC28: Na+-coupled nucleoside transporter
B SLC29: Facilitative nucleoside transporter
B SLC30: Zinc efflux transporter
B SLC31: Copper transporter
B SLC32: Vesicular inhibitory amino acid transporter
B SLC33: Acetyl-CoA transporter
B SLC34: Type II Na+-phosphate cotransporter
B SLC35: Nucleoside-sugar transporter
B SLC36: Proton-coupled amino acid transporter
B SLC37: Sugar-phosphate/phosphate exchanger
B SLC38: System A and System N sodium-coupled neutral amino acid transporter
B SLC39: Metal ion transporter
B SLC40: Basolateral iron transporter
B SLC41: MgtE-like magnesium transporter
B SLC42: Rh ammonium transporter
B SLC43: Na+-independent, system-L-like amino acid transporter
B SLC44: Choline-like transporter
B SLC45: H+/sugar cotransporter
B SLC46: Folate transporter
B SLC47: Multidrug and Toxin Extrusion (MATE) family
C SpyM50041 multi antimicrobial extrusion (MATE) family transporter K26937 dinF; MATE family, multidrug efflux pump
B SLC48: Heme transporter
B SLC49: FLVCR-related transporter
B SLC50: Sugar efflux transporter
B SLC51: Transporter of steroid-derived molecules
B SLC52: Riboflavin transporter
B SLC54: Mitochondrial pyruvate carrier
B SLC56: Sideroflexin
B SLC57: NiPA-like magnesium transporter
B SLC58: MagT-like magnesium transporter
B SLC62: Pyrophosphate transporter
B SLC65: NPC-type cholesterol transporter
B SLC66: Lysosomal lysine-arginine transporter
#
AMajor facilitator superfamily (MFS)
B Sugar transporters
C Sugar porter (SP) family [TC:2.A.1.1]
C Oligosaccharide:H+ symporter (OHS) family [TC:2.A.1.5]
C Fucose:H+ symporter (FHS) family [TC:2.A.1.7]
C Sugar efflux transporter (SET) [TC:2.A.1.20]
C Nucleoside:H+ symporter (NHS) family [TC:2.A.1.10]
C N-Acetylglucosamine transporter (NAG-T) family [TC:2.A.1.58]
B Organic acid transporters
C Metabolite:H+ symporter (MHS) family [TC:2.A.1.6]
C Oxalate:formate antiporter (OFA) family [TC:2.A.1.11]
D SpyM50723 major facilitator superfamily protein K08177 oxlT; MFS transporter, OFA family, oxalate/formate antiporter
C Sialate:H+ symporter (SHS) family [TC:2.A.1.12]
C Monocarboxylate transporter (MCT) family [TC:2.A.1.13]
C Anion:cation symporter (ACS) family [TC:2.A.1.14]
C Aromatic acid:H+ symporter (AAHS) family [TC:2.A.1.15]
C Cyanate porter (CP) family [TC:2.A.1.17]
C Organic cation transporter (OCT) family [TC:2.A.1.19]
C Phenylproprionate permease (PPP) [TC:2.A.1.27]
C L-Amino acid transporter-3 (LAT3) family (SLC43 family) [TC:2.A.1.44]
C Proton coupled folate transporter/heme carrier protein (PCFT/HCP) family [TC:2.A.1.50]
B Phosphate and organophosphate transporters
C Phosphate:H+ symporter (PHS) family [TC:2.A.1.9]
C Organophosphate:Pi antiporter (OPA) family [TC:2.A.1.4]
D SpyM51504 putative glycerol-3-phosphate transporter K02445 glpT; MFS transporter, OPA family, glycerol-3-phosphate transporter
C 1-Arseno-3-phosphoglycerate exporter (APGE) family [TC:2.A.1.83]
B Nitrate/nitrite transporters
C Nitrate/nitrite porter (NNP) family [TC:2.A.1.8]
C Proton-dependent oligopeptide transporter (POT/PTR) family [TC:2.A.17]
B Lipid transporters
C Lysophospholipid transporter (LplT) family [TC:2.A.1.42]
C Sphingosine-1-phosphate transporter (Spinster) family [TC:2.A.1.49]
B Metal transporters
C Siderophore-iron transporter (SIT) family [TC:2.A.1.16]
C Enterobactin (siderophore) exporter (EntS) family [TC:2.A.1.38]
C Nickel resistance (Nre) family [TC:2.A.1.31]
C MFS domain-containing protein family [TC:2.A.1.40]
C Putative bacteriochlorophyll delivery (BCD) family [TC:2.A.1.41]
B Protein transporters
C Vesicular neurotransmitter transporter (VNT) [TC:2.A.1.22]
C Peptide-acetyl-CoA transporter (PAT) [TC:2.A.1.25]
C Feline leukemia virus subgroup C receptor (FLVCR) [TC:2.A.1.28]
B Drug transporters
C Drug:H+ antiporter-1 (12 spanner) (DHA1) family [TC:2.A.1.2]
D SpyM51458 pmrA; multi-drug resistance efflux pump K08161 mdtG; MFS transporter, DHA1 family, multidrug resistance protein
D SpyM51762 lmrP; putative transporter protein K08152 lmrP; MFS transporter, DHA1 family, multidrug resistance protein B
C Drug:H+ antiporter-2 (14 spanner) (DHA2) family [TC:2.A.1.3]
D SpyM51387 major facilitator superfamily protein K18926 lmrB; MFS transporter, DHA2 family, lincomycin resistance protein
C Drug:H+ antiporter-3 (12 spanner) (DHA3) [TC:2.A.1.21]
C Putative aromatic compound/drug exporter (ACDE) family [TC:2.A.1.32]
C Fosmidomycin resistance (Fsr) family [TC:2.A.1.35]
C Acriflavin-sensitivity (YnfM) family [TC:2.A.1.36]
C Glycerophosphodiester uptake (GlpU) family [TC:2.A.1.52]
B Unknown transporters
C Unknown major facilitator-1 (UMF1) [TC:2.A.1.24]
C Unknown major facilitator-2 (UMF2) [TC:2.A.1.26]
C Putative YqgE transporter (YqgE) family [TC:2.A.1.33]
C Others
#
APhosphotransferase system (PTS)
B Enzyme I and HPr
C Enzyme I [TC:8.A.7]
D SpyM50740 pstI; phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]
C Phosphocarrier protein HPr [TC:8.A.8]
D SpyM50739 ptsH; histidine-containing phosphocarrier protein (HPr) K02784 ptsH; phosphocarrier protein HPr
C Multiphosphoryl transfer protein
B Enzyme II [TC:4.A]
C Glucose-specific II component
C Glucose-specific II component
C N-Acetylglucosamine-specific II component
C Maltose/glucose-specific II component
C Maltose-specific II component
D SpyM51662 putative glucose-specific phosphotransferase system (PTS), IIABC component K20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208]
C D-Glucosamine-specific II component
C Sucrose-specific II component
D SpyM50308 scrA; putative sucrose-specific phosphotransferase system (PTS), IIABC component K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211]
C Beta-glucoside-specific II component
D SpyM51385 beta-glucoside-specific phosphotransferase system (PTS), IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-]
C Beta-glucoside (arbutin/salicin/cellobiose)-specific II component
C Trehalose-specific II component
D SpyM51743 sugar phosphotransferase system (PTS), IIABC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201]
C N-Acetylmuramic acid-specific II component
C Alpha-glucoside-specific II component
C Fructose-specific II component
D SpyM51146 fruA; putative fructose-specific phosphotransferase system (PTS), IIABC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202]
C Fructose-specific II-like component
C Mannitol-specific II component
C 2-O-A-Mannosyl-D-glycerate-specific II component
C Lactose-specific II component
D SpyM51609 lacF; putative lactose-specific phosphotransferase system (PTS), IIA component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207]
D SpyM51608 lacE; putative lactose-specific phosphotransferase system (PTS), IIBC component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207]
C Cellobiose-specific II component
D SpyM50784 putative lactose/cellobiose-specific phosphotransferase system (PTS), IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D SpyM51709 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D SpyM50783 putative lactose/cellobiose-specific phosphotransferase system (PTS), IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]
D SpyM51708 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]
D SpyM51707 sugar phosphotransferase system (PTS), IIC component K02761 celB; cellobiose PTS system EIIC component
D SpyM50786 sugar phosphotransferase system (PTS), IIC component K02761 celB; cellobiose PTS system EIIC component
C Glucitol/sorbitol-specific II component
C Galactitol-specific II component
C Galactose-specific II component
D SpyM50389 sugar phosphotransferase system (PTS), IIA component K20112 gatA; galactose PTS system EIIA component [EC:2.7.1.204]
D SpyM50390 sugar phosphotransferase system (PTS), IIB component K20113 gatB; galactose PTS system EIIB component [EC:2.7.1.204]
D SpyM50391 sugar phosphotransferase system (PTS),galactitol-specific family, IIC component K20114 gatC; galactose PTS system EIIC component
C Mannose-specific II component
C Mannose-specific II component
D SpyM50366 manL; putative mannose-specific phosphotransferase system (PTS), IIAB component K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191]
D SpyM50986 sugar phosphotransferase system (PTS),mannose/fructose family, IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
D SpyM50365 manM; putative mannose-specific phosphotransferase system (PTS), IIC component K02795 manY; mannose PTS system EIIC component
D SpyM50984 sugar phosphotransferase system (PTS),mannose/fructose family, IIC component K02795 manY; mannose PTS system EIIC component
D SpyM50364 manN; putative mannose-specific phosphotransferase system (PTS), IID component K02796 manZ; mannose PTS system EIID component
D SpyM50983 sugar phosphotransferase system (PTS),mannose/fructose family, IID component K02796 manZ; mannose PTS system EIID component
C Fructoselysine/glucoselysine-specific II component
D SpyM50985 sugar phosphotransferase system (PTS),mannose/fructose family, IIB component K19507 gfrB; fructoselysine/glucoselysine PTS system EIIB component [EC:2.7.1.-]
C Fructose-specific II component
C Sorbose-specific II component
C N-Acetylgalactosamine-specific II component
D SpyM51340 putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIA component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-]
D SpyM51342 agaV; putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIB component K02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-]
D SpyM51343 agaW; putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIC component K02746 agaW; N-acetylgalactosamine PTS system EIIC component
D SpyM51344 agaD; putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IID component K02747 agaE; N-acetylgalactosamine PTS system EIID component
C Galactosamine-specific II component
D SpyM51340 putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIA component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-]
C D-Glucosaminate-specific II component
C Ascorbate-specific II component
D SpyM50144 sugar phosphotransferase system (PTS), IIA component K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]
D SpyM51637 putative PTS multi-domain regulator K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]
D SpyM50143 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D SpyM51636 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D SpyM51635 putative sugar-specific permease K03475 ulaA; ascorbate PTS system EIIC component
D SpyM50142 putative sugar-specific permease, SgaT/UlaA family K03475 ulaA; ascorbate PTS system EIIC component
C Nitrogen regulatory II component
C EI/HPr/EIIA hybrid protein
D SpyM51435 sugar phosphotransferase system (PTS), fructose family, IIA component K05881 dhaM; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaM [EC:2.7.1.121]
#
AOther transporters
B Aquaporins and small neutral solute transporters [TC:1.A.8]
C Aquaporins
C Aquaglyceroporins or glycerol-uptake facilitators
D SpyM50411 glpF1; glycerol uptake facilitator protein 1 K02440 glpF; glycerol uptake facilitator
D SpyM51434 glpF2; glycerol uptake facilitator protein 2 K02440 glpF; glycerol uptake facilitator
D SpyM50277 gla; glycerol facilitator-aquaporin K02440 glpF; glycerol uptake facilitator
B Pores ion channels [TC:1]
C SpyM51088 hypothetical protein K00799 GST; glutathione S-transferase [EC:2.5.1.18]
C SpyM50699 putative formate/nitrite transporter family protein K21993 fdhC; formate transporter
C SpyM51209 mscL; large-conductance mechanosensitive channel K03282 mscL; large conductance mechanosensitive channel
C SpyM50241 mechanosensitive ion channel protein K22044 ybiO; moderate conductance mechanosensitive channel
C SpyM50299 CorA-like Mg2+ transporter protein K03284 corA; magnesium transporter
C SpyM51541 putative transport protein K03699 tlyC; magnesium and cobalt exporter, CNNM family
C SpyM51034 putative phage minor tail protein K21449 ata; trimeric autotransporter adhesin
B Electrochemical potential-driven transporters [TC:2]
C SpyM51155 cation efflux family protein K16264 czcD; cobalt-zinc-cadmium efflux system protein
C SpyM51829 putative sugar uptake protein K05340 glcU; glucose uptake protein
C SpyM51580 sodium:dicarboxylate symporter family protein K07862 sstT; serine/threonine transporter
C SpyM51578 cation transport protein K03498 trkH; trk/ktr system potassium uptake protein
C SpyM51579 TrkA family transport protein K03499 trkA; trk/ktr system potassium uptake protein
C SpyM51167 pyrP; uracil permease K02824 uraA; uracil permease
C SpyM50931 pbuX; putative xanthine permease K16169 pbuX; xanthine permease
C SpyM50368 putative permease K06901 pbuG; adenine/guanine/hypoxanthine permease
C SpyM50952 voltage gated chloride channel family protein K03281 clcA; chloride channel protein, CIC family
C SpyM50734 voltage gated chloride channel K03281 clcA; chloride channel protein, CIC family
C SpyM51254 voltage gated chloride channel protein K03281 clcA; chloride channel protein, CIC family
C SpyM50401 putative Na+/Pi-cotransporter protein K03324 yjbB; phosphate:Na+ symporter
C SpyM50707 probable potassium transport system protein K03549 kup; KUP system potassium uptake protein
C SpyM51545 putative membrane protein K23675 fmnP; riboflavin transporter
C SpyM51364 putative membrane protein K16789 thiT; thiamine transporter
C SpyM50698 putative membrane protein K16788 niaX; niacin transporter
C SpyM51357 ftsW; putative cell division protein K03588 ftsW; cell division protein FtsW
B Primary active transporters [TC:3]
C SpyM50900 putative glutaconyl-CoA decarboxylase beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]
C SpyM50894 putative Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]
C SpyM50888 putative carboxylase subunit K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2]
C SpyM50903 putative carboxylase subunit K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2]
C SpyM50902 putative membrane protein K01573 oadG; oxaloacetate decarboxylase (Na+ extruding) subunit gamma
C SpyM50901 putative glutaconyl-CoA decarboxylase gamma subunit K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma
C SpyM50895 putative decarboxylase gamma chain K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma
B Transmembrane electron carriers [TC:5]
C SpyM50568 putative cytochrome c-type biogenesis protein K06196 ccdA; cytochrome c-type biogenesis protein
B Accessory factors involved in transport [TC:8]
C SpyM51691 putative exported protein K24950 yknX; membrane fusion protein, antimicrobial resistance system
C SpyM51163 putative exported protein K24950 yknX; membrane fusion protein, antimicrobial resistance system
B Others
C SpyM50779 nicotinamide mononucleotide transporter K03811 pnuC; nicotinamide mononucleotide transporter
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 13, 2024
#
ABC classifications based on Igarashi et al. (2004) and Tomii & Kanehisa (1998)
#
MFS classification taken from TCDB