+C	Peptidoglycan biosynthesis and degradation proteins	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Peptidoglycan Biosynthesis and Degradation Proteins - Staphylococcus aureus subsp. aureus HO 5096 0412 (MRSA)</h2>
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A<b>Precursor biosynthesis</b>
B  Transferase/Dehydrogenase
C    SAEMRSA15_20080 murA1; putative UDP-N-acetylglucosamine 1-carboxyvinyltransferase	K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] 
C    SAEMRSA15_20320 murA2; putative UDP-N-acetylglucosamine 1-carboxyvinyltransferase	K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] 
C    SAEMRSA15_06640 murB; putative UDP-N-acetylenolpyruvoylglucosamine reductase	K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] 
B  Amino acid ligase
C    SAEMRSA15_16480 murC; UDP-N-acetylmuramate--alanine ligase	K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] 
C    SAEMRSA15_10160 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase	K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] 
C    SAEMRSA15_08480 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-dia minopimelate ligase	K05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7] 
C    SAEMRSA15_19920 D-alanine--D-alanine ligase	K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] 
C    SAEMRSA15_21600 fmhB; putative peptidoglycan pentaglycine interpeptide biosynthesis protein	K11693 femX; peptidoglycan pentaglycine glycine transferase (the first glycine) [EC:2.3.2.16] 
C    SAEMRSA15_12220 femA; factor essential for expression of methicillin resistance	K11694 femA; peptidoglycan pentaglycine glycine transferase (the second and third glycine) [EC:2.3.2.17] 
C    SAEMRSA15_12230 femB; putative methicillin resistance expression factor	K11695 femB; peptidoglycan pentaglycine glycine transferase (the fourth and fifth glycine) [EC:2.3.2.18] 
B  Racemase
C    SAEMRSA15_19800 alr; alanine racemase	K01775 alr; alanine racemase [EC:5.1.1.1] 
C    SAEMRSA15_12620 dal; putative alanine racemase	K01775 alr; alanine racemase [EC:5.1.1.1] 
C    SAEMRSA15_09800 murI; putative glutamate racemase	K01776 murI; glutamate racemase [EC:5.1.1.3] 
B  Carboxypeptidase
B  Glycosyltransferase
C    SAEMRSA15_10150 mraY; phospho-N-acetylmuramoyl-pentapeptide-transfera se	K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] 
C    SAEMRSA15_12810 murG; putative UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyr ophosphoryl-undecaprenol N-acetylglucosamine transferase	K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] 
B  Diphosphatase
C    SAEMRSA15_06090 bacA; putative undecaprenol kinase	K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] 
C    SAEMRSA15_12800 putative membrane protein	K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] 
B  Flippase
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A<b>Peptidoglycan biosynthesis and degradation</b>
B  Glycosyltransferase/DD-Transpeptidase (Class A PBP)
C    SAEMRSA15_13110 pbp2; penicillin-binding protein 2	K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] 
B  DD-Transpeptidase (Class B PBP)
C    SAEMRSA15_00310 mecA; penicillin-binding protein 2 prime	K02545 mecA; penicillin-binding protein 2 prime [EC:3.4.16.4] 
C    SAEMRSA15_10140 pbpA; penicillin-binding protein 1	K12552 pbpA; penicillin-binding protein 1 [EC:3.4.-.-] 
C    SAEMRSA15_14720 pbpF; penicillin-binding protein PBP2B	K12553 pbp3; penicillin-binding protein 3 [EC:3.4.-.-] 
B  DD-Carboxypeptidase/DD-Endopeptidase (Low molecular weight PBP)
C    SAEMRSA15_05680 pbp4; penicillin-binding protein 4	K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] 
B  Glycosyltransferase
C    SAEMRSA15_16380 putative transglycosylase	K12551 sgtA; monofunctional glycosyltransferase [EC:2.4.99.28] 
C    SAEMRSA15_17810 putative transglycosylase	K04478 sgtB; monofunctional glycosyltransferase [EC:2.4.99.28] 
B  Transpeptidase
B  Carboxypeptidase
B  Endopeptidase
C    SAEMRSA15_12370 putative exported protein	K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] 
C    SAEMRSA15_01710 putative peptidase	K21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-] 
C    SAEMRSA15_02350 lytM; peptidoglycan hydrolase	K08259 lytM; lysostaphin [EC:3.4.24.75] 
B  Sortase
C    SAEMRSA15_24270 srtA; sortase A	K07284 srtA; sortase A [EC:3.4.22.70] 
C    SAEMRSA15_09640 srtB; sortase B	K08600 srtB; sortase B [EC:3.4.22.71] 
B  Lytic transglycosylase
B  Amidase
C    SAEMRSA15_15490 putative N-acetylmuramoyl-L-alanine amidase	K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] 
B  Structural protein
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#Last updated: January 30, 2024