+C Kinase KO
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Protein Kinases - Tribolium castaneum (red flour beetle)
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ASerine/threonine kinases: AGC group
B PKA family
C 657232 cGMP-dependent protein kinase, isozyme 1 K04345 PKA; protein kinase A [EC:2.7.11.11]
C 656552 Pka-C1; cAMP-dependent protein kinase 1 K04345 PKA; protein kinase A [EC:2.7.11.11]
C 655660 cAMP-dependent protein kinase catalytic subunit beta K04345 PKA; protein kinase A [EC:2.7.11.11]
C 661839 protein kinase DC2 K19584 PRKX; protein kinase X [EC:2.7.11.11]
B PKG family
C 657149 cGMP-dependent protein kinase, isozyme 1 K07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
B PKC family [OT]
C 656250 protein kinase C, brain isozyme-like K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
C 658064 putative protein kinase C delta type homolog K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
C 663551 Pkc98E; calcium-independent protein kinase C K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
C 103313855 protein kinase C-like K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
C 663080 atypical protein kinase C K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
B PKN family
C 659637 serine/threonine-protein kinase N K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
B AUR family [OT]
C 656727 Aurka; aurora kinase A K11481 AURKA; aurora kinase A [EC:2.7.11.1]
C 103314617 aurB; aurora kinase C K11479 AURKB; aurora kinase B [EC:2.7.11.1]
B PDK1 family
C 661920 3-phosphoinositide-dependent protein kinase 1 K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
B AKT/PKB family
C 656423 RAC serine/threonine-protein kinase K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
B SGK family [OT]
B RSK family [OT]
C 664211 ribosomal protein S6 kinase 2 beta K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
C 658616 ribosomal protein S6 kinase alpha-5 K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
C 661481 ribosomal protein S6 kinase beta-2 K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
C 103313562 ribosomal protein S6 kinase delta-1 K20839 RSKL; ribosomal protein S6 kinase-like
B NDR family
C 655192 serine/threonine-protein kinase tricorner K08790 STK38; serine/threonine kinase 38 [EC:2.7.11.1]
C 661996 serine/threonine-protein kinase Warts K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
B MAST family [OT]
C 661405 microtubule-associated serine/threonine-protein kinase 3 K08789 MAST; MAST-subfamily protein kinase [EC:2.7.11.37]
B YANK family
C 655011 serine/threonine-protein kinase 32B K08793 STK32; serine/threonine kinase 32 [EC:2.7.11.1]
B DMPK family [OT]
C 663533 rho-associated protein kinase 1 K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
C 660018 serine/threonine-protein kinase Genghis Khan K16307 CDC42BP; serine/threonine-protein kinase MRCK [EC:2.7.11.1]
C 657732 citron Rho-interacting kinase K16308 CIT; citron Rho-interacting kinase [EC:2.7.11.35]
B GRK family [OT]
C 654946 G protein-coupled receptor kinase 1 K00910 ADRBK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
C 656376 G protein-coupled receptor kinase 2 K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
B Other
C 660619 serine/threonine-protein kinase S6KL K17529 SGK494; uncharacterized serine/threonine-protein kinase SgK494 [EC:2.7.11.1]
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ASerine/threonine kinases: CAMK group
B CAMK1 family [OT]
C 656309 calcium/calmodulin-dependent protein kinase type 1 K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
B CAMK2 family
C 655266 calcium/calmodulin-dependent protein kinase type II alpha chain K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
B CAMKL family
C 661101 serine/threonine-protein kinase BRSK2 K08796 BRSK; BR serine/threonine kinase [EC:2.7.11.1]
C 656926 par-1; par-1 protein kinase K08798 MARK; MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
C 103312366 maternal embryonic leucine zipper kinase K08799 MELK; maternal embryonic leucine zipper kinase [EC:2.7.11.1]
C 663357 Snf1a; SNF1A/AMP-activated protein kinase K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
C 658197 serine/threonine-protein kinase SIK2 K16311 SIK2; serine/threonine-protein kinase SIK2 [EC:2.7.11.1]
C 100142375 serine/threonine-protein kinase SIK3 K19009 SIK3; serine/threonine-protein kinase SIK3 [EC:2.7.11.1]
C 661123 SNF-related serine/threonine-protein kinase K08802 SNRK; SNF related kinase [EC:2.7.11.1]
C 662493 Stk11; polarization-related protein LKB1 K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
B DAPK family
C 661340 death-associated protein kinase 1 K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
C 661947 death-associated protein kinase-like K08804 STK17; serine/threonine kinase 17 [EC:2.7.11.1]
B DCAMKL family
C 655891 serine/threonine-protein kinase GL21140 K08805 DCLK1_2; doublecortin-like kinase 1/2 [EC:2.7.11.1]
B MAPKAPK family [OT]
C 662443 MAP kinase-activated protein kinase 2 K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
C 658754 MAP kinase-interacting serine/threonine-protein kinase 1 K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
B MLCK family
C 659444 myosin light chain kinase, smooth muscle K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
C 660101 titin homolog K12567 TTN; titin [EC:2.7.11.1]
B PHK family
C 655530 phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
B PIM family [OT]
B PKD family
C 663691 serine/threonine-protein kinase D3 K06070 PKD; protein kinase D [EC:2.7.11.13]
B PSK family
B RAD53 family
C 661264 serine/threonine-protein kinase Chk2 K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
B Trio family [OT]
C 656919 kalirin K08810 TRIO; triple functional domain protein [EC:2.7.11.1]
B TSSK family
C 664570 testis-specific serine/threonine-protein kinase 1 K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
C 660054 testis-specific serine/threonine-protein kinase 3 K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
C 659657 testis-specific serine/threonine-protein kinase 4 K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
B CDPK family
B CASK family
C 656749 peripheral plasma membrane protein CASK K06103 CASK; calcium/calmodulin-dependent serine protein kinase [EC:2.7.11.1]
B Trbl family
C 659518 tribbles homolog 2 K08814 TRIB1_2; tribbles homolog 1/2
B Other
C 662367 serine/threonine-protein kinase 33 K08813 STK33; serine/threonine kinase 33 [EC:2.7.11.1]
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ASerine/threonine kinases: CK1 group
B CK1 family [OT]
C 662101 casein kinase I isoform alpha K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
C 655326 casein kinase I isoform gamma-3 K08958 CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]
C 662202 casein kinase I isoform gamma-3 K08958 CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]
C 661388 casein kinase I isoform delta-A K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
B TTBK family
C 659527 actin cytoskeleton-regulatory complex protein PAN1 K08815 TTBK; tau tubulin kinase [EC:2.7.11.26]
B VRK family
C 656414 serine/threonine-protein kinase VRK1 K08816 VRK; vaccinia related kinase [EC:2.7.11.1]
C 661614 serine/threonine-protein kinase VRK1 K08816 VRK; vaccinia related kinase [EC:2.7.11.1]
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ASerine/threonine kinases: CMGC group
B CDK family
C 655288 cyclin-dependent kinase 20 K08817 CCRK; cell cycle related kinase [EC:2.7.11.22]
C 662461 cdk10/11-like protein K08818 CDC2L; cell division cycle 2-like [EC:2.7.11.22]
C 662494 cyclin-dependent kinase 11B K08818 CDC2L; cell division cycle 2-like [EC:2.7.11.22]
C 656189 cyclin-dependent kinase 1 K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
C 103314472 cdc2; cyclin-dependent kinase 2 K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
C 103313355 cyclin-dependent kinase 1-like K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
C 663975 cyclin-dependent kinase 6 K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
C 661807 cyclin-dependent-like kinase 5 K02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
C 655114 cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
C 660461 cdk8; cyclin dependent kinase 8 K02208 CDK8_11; cyclin-dependent kinase 8/11 [EC:2.7.11.22 2.7.11.23]
C 660097 cyclin-dependent kinase 9 K02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]
C 663347 cyclin-dependent kinase 10 K02449 CDK10; cyclin-dependent kinase 10 [EC:2.7.11.22]
C 664031 cyclin-dependent kinase 12 K08819 CDK12_13; cyclin-dependent kinase 12/13 [EC:2.7.11.22 2.7.11.23]
C 657012 cyclin-dependent kinase 14 K08821 CDK14; cyclin-dependent kinase 14 [EC:2.7.11.22]
B MAPK family [OT]
C 655225 mitogen-activated protein kinase 1 K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
C 662230 extracellular signal-regulated kinase 2 K19603 MAPK15; mitogen-activated protein kinase 15 [EC:2.7.11.24]
C 663836 bsk; basket K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
C 660539 mitogen-activated protein kinase 14B K04441 P38; p38 MAP kinase [EC:2.7.11.24]
C 659674 serine/threonine-protein kinase NLK K04468 NLK; nemo like kinase [EC:2.7.11.24]
B GSK family [OT]
C 664299 sgg; shaggy K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
B CLK family
C 659421 serine/threonine-protein kinase Doa K08823 CLK2_3; dual specificity protein kinase CLK2/3 [EC:2.7.12.1]
B CDKL family
C 662169 cyclin-dependent kinase-like 4 K08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]
C 661805 cyclin-dependent kinase-like 1 K08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]
B DYRK family [OT]
C 661419 dual specificity tyrosine-phosphorylation-regulated kinase 2 K18669 DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1]
C 661500 homeodomain-interacting protein kinase 2 K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
C 657605 serine/threonine-protein kinase PRP4 homolog K08827 PRPF4B; serine/threonine-protein kinase PRP4 [EC:2.7.11.1]
B RCK family [OT]
C 659491 serine/threonine-protein kinase MAK K08829 MAK; male germ cell-associated kinase [EC:2.7.11.22]
B SRPK family [OT]
C 656905 SRSF protein kinase 1 K15409 SRPK1; serine/threonine-protein kinase SRPK1 [EC:2.7.11.1]
C 657236 SRSF protein kinase 1 K08832 SRPK3; serine/threonine-protein kinase SRPK3 [EC:2.7.11.1]
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ASerine/threonine kinases: STE group
B STE7 family
C 661995 dual specificity mitogen-activated protein kinase kinase dSOR1 K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
C 661608 dual specificity mitogen-activated protein kinase kinase 6 K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
C 662917 dual specificity mitogen-activated protein kinase kinase 4 K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
C 103315236 hep; dual specificity mitogen-activated protein kinase kinase 7 K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
B STE20 family
C 655348 mitogen-activated protein kinase kinase kinase kinase 5 K08833 MAP4K5; mitogen-activated protein kinase kinase kinase kinase 5 [EC:2.7.11.1]
C 656940 serine/threonine-protein kinase mig-15 K08840 TNIK; TRAF2 and NCK interacting kinase [EC:2.7.11.1]
C 656684 Myo21; myosin 21 K08834 MYO3; myosin III [EC:2.7.11.1]
C 663653 serine/threonine-protein kinase OSR1 K08835 OXSR1; serine/threonine-protein kinase OSR1/STK39 [EC:2.7.11.1]
C 656127 serine/threonine-protein kinase PAK 3 K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
C 663345 STE20-like serine/threonine-protein kinase K08836 SLK; STE20-like kinase [EC:2.7.11.1]
C 663780 STE20-related kinase adapter protein alpha K08271 STRADA; STE20-related kinase adapter protein alpha
C 658552 serine/threonine-protein kinase 3 K04412 STK3; serine/threonine kinase 3
C 103313200 serine/threonine-protein kinase 26 K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
B STE11 family
C 663503 mitogen-activated protein kinase kinase kinase 4 K04428 MAP3K4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
C 661249 mitogen-activated protein kinase kinase kinase 15 K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
B Other
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ASerine/threonine kinases: TKL group
B IRAK family
C 654877 IL-1; pelle K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
C 663280 probable receptor-like protein kinase At5g18500 K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
B LISK family [OT]
C 657421 LIM domain kinase 1 K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
C 659807 dual specificity testis-specific protein kinase 2 K08842 TESK2; testis-specific kinase 2 [EC:2.7.12.1]
B LRRK family
B MLK family
C 656961 Tak1; TGF-beta activated kinase 1 K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
C 664510 mitogen-activated protein kinase kinase kinase 11 K04417 MAP3K9; mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]
C 661365 mitogen-activated protein kinase kinase kinase 13 K04422 MAP3K13; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]
C 655116 integrin-linked protein kinase K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
B RAF family [OT]
C 655334 raf; raf kinase, effector of Ras K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
C 661985 kinase suppressor of Ras 2 K18529 KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]
B RIPK family [OT]
B Other
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ASerine/threonine kinases: Other
B RGC family [OT]
C 664507 atrial natriuretic peptide receptor 1 K12323 ANPRA; atrial natriuretic peptide receptor A [EC:4.6.1.2]
C 100141543 GLEAN_04747; receptor type guanylyl cyclase-like K12323 ANPRA; atrial natriuretic peptide receptor A [EC:4.6.1.2]
C 661745 retinal guanylyl cyclase 2 K12322 GUCY2F; guanylate cyclase 2F [EC:4.6.1.2]
B BUB family
C 660046 Bub1; mitotic checkpoint serine/threonine-protein kinase BUB1 beta K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
B Bud32 family
C 658924 TP53-regulating kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
B CAMKK family
C 661026 calcium/calmodulin-dependent protein kinase kinase 2 K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
B CDC7 family
B CK2 family
C 660746 casein kinase II subunit alpha K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
C 662984 casein kinase II subunit alpha K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
B Haspin family
C 659764 uncharacterized LOC659764 K16315 GSG2; serine/threonine-protein kinase haspin [EC:2.7.11.1]
B IKK family [OT]
C 655324 inhibitor of nuclear factor kappa-B kinase subunit beta K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
C 658393 ikkb; inhibitor of nuclear factor kappa-B kinase subunit beta K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
C 658218 ik2; IKK epsilon K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
C 100141977 serine/threonine-protein kinase TBK1 K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
B IRE family
C 658142 serine/threonine-protein kinase/endoribonuclease IRE1 K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
B MOS family
C 103315222 serine/threonine-protein kinase mos K04367 MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
B NAK family [OT]
C 660568 protein sel-5 K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
C 655547 cyclin-G-associated kinase K08855 GAK; cyclin G-associated kinase [EC:2.7.11.1]
C 663367 serine/threonine-protein kinase 16 K08856 STK16; serine/threonine kinase 16 [EC:2.7.11.1]
B NEK family
C 662248 serine/threonine-protein kinase Nek8 K20877 NEK8; serine/threonine-protein kinase Nek8 [EC:2.7.11.1]
B NKF1 family
C 655263 serine/threonine-protein kinase SBK1 K08858 SBK; serine/threonine-protein kinase SBK [EC:2.7.11.1]
B NKF2 family
C 656767 serine/threonine-protein kinase PINK1, mitochondrial K05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
B NKF3 family
B NKF4 family
B NKF5 family
B NRBP family
C 661173 nuclear receptor-binding protein homolog K08875 NRBP; nuclear receptor-binding protein
B PEK family [OT]
C 100142127 eIF-2-alpha kinase GCN2 K16194 EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
C 103313061 eIF-2-alpha kinase GCN2 K16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
C 658953 eIF-2-alpha kinase GCN2 K16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
B PLK family [OT]
C 660822 polo; polo K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
C 663303 serine/threonine-protein kinase PLK4 K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
B SCY1 family [OT]
C 664388 N-terminal kinase-like protein K08876 SCYL1; SCY1-like protein 1
C 657615 SCY1-like protein 2 K17541 SCYL2; SCY1-like protein 2
C 661144 SCY1-like protein 2 K17541 SCYL2; SCY1-like protein 2
C 660581 protein-associating with the carboxyl-terminal domain of ezrin K17542 SCYL3; SCY1-like protein 3
B Slob family
C 660832 PX domain-containing protein kinase-like protein K17543 PXK; PX domain-containing protein kinase-like protein
C 656032 slowpoke-binding protein K17543 PXK; PX domain-containing protein kinase-like protein
B TBCK family
C 657002 TBC domain-containing protein kinase-like protein K17544 TBCK; TBC domain-containing protein kinase-like protein
B TLK family
C 655717 serine/threonine-protein kinase tousled-like 2 K08864 TLK; tousled-like kinase [EC:2.7.11.1]
B TOPK family
B TTK family
C 662564 ald; altered disjunction K08866 TTK; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
B ULK family [OT]
C 657139 serine/threonine-protein kinase fused K06228 FU; fused [EC:2.7.11.1]
C 659114 serine/threonine-protein kinase unc-51 K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
B VPS15 family
C 659265 phosphoinositide 3-kinase regulatory subunit 4 K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
B WEE family
C 659898 membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase K06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
C 657501 wee1-like protein kinase K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
B Wnk family
C 103313773 uncharacterized LOC103313773 K08867 WNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
B ABC1 family
C 654981 uncharacterized aarF domain-containing protein kinase 5 K08869 ADCK; aarF domain-containing kinase
C 660265 uncharacterized aarF domain-containing protein kinase 1 K08869 ADCK; aarF domain-containing kinase
C 664206 aarF domain-containing protein kinase 4 K08869 ADCK; aarF domain-containing kinase
B Alpha family [OT]
B BCR family
B BRD family [OT]
B FAST family
B G11 family
B H11 family
B PDHK family [OT]
C 662090 pyruvate dehydrogenase (acetyl-transferring) kinase, mitochondrial K00898 PDK2_3_4; pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]
B PIKK family [OT]
C 660142 serine-protein kinase ATM K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
C 655218 ATR; serine/threonine-protein kinase ATR K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
C 660499 serine/threonine-protein kinase mTOR K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
C 659348 DNA-dependent protein kinase catalytic subunit K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
C 658025 serine/threonine-protein kinase SMG1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
C 662083 transformation/transcription domain-associated protein K08874 TRRAP; transformation/transcription domain-associated protein
B RIO family [OT]
C 660167 serine/threonine-protein kinase RIO1 K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
C 655344 serine/threonine-protein kinase RIO2 K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
C 664050 serine/threonine-protein kinase RIO3 K08872 RIOK3; RIO kinase 3 [EC:2.7.11.1]
B TAF1 family
C 658493 transcription initiation factor TFIID subunit 1 K03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]
B TIF1 family [OT]
B Other
C 656602 protein mahjong K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
C 657492 dual serine/threonine and tyrosine protein kinase K16288 DSTYK; dual serine/threonine and tyrosine protein kinase [EC:2.7.12.1]
B Bacterial family
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AReceptor serine/threonine kinases (RSTK): TKL group
B TGFBR1 family [OT]
C 658545 sax; saxophone K04675 ACVR1; activin receptor type-1 [EC:2.7.11.30]
C 659260 thickveins; bone morphogenetic protein receptor type-1B K13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
C 659969 babo; TGF-beta receptor type-1 K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
B TGFBR2 family [OT]
C 654851 punt; activin receptor type-2A K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
C 663692 wit; wishful thinking K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
C 658911 Alp23B; dawdle K04669 TGFBRX; TGF-beta receptor, other
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AReceptor tyrosine kinases (RTK)
B EGFR family [OT]
C 660037 DER; epidermal growth factor receptor K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
B INSR family [OT]
C 661524 InR; insulin-like receptor K04527 INSR; insulin receptor [EC:2.7.10.1]
B PDGFR family [OT]
B FGFR family [OT]
C 659961 Cad96Ca; tyrosine kinase receptor Cad96Ca K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
C 659434 DFR1; fibroblast growth factor receptor homolog 1 K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
B VEGFR family [OT]
C 662470 vascular endothelial growth factor receptor 1 K05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
B MET family
B TRK family [OT]
B EPH family [OT]
C 658635 Eph; ephrin type-A receptor 4-B K05110 EPHB1; Eph receptor B1 [EC:2.7.10.1]
B AXL family
B ALK family
C 657445 ALK tyrosine kinase receptor K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
B TIE family
C 662769 putative tyrosine-protein kinase Wsck K05121 TEK; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
B ROR family
C 663368 tyrosine-protein kinase transmembrane receptor Ror K05122 ROR1; receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1]
B DDR family
C 655103 epithelial discoidin domain-containing receptor 1 K05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]
C 657304 discoidin domain-containing receptor 2 K05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]
C 100142401 discoidin domain-containing receptor 2 K05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]
C 657382 discoidin domain-containing receptor 2 K05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]
C 657229 discoidin domain-containing receptor 2 K05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]
B RET family
C 657748 ret; proto-oncogene tyrosine-protein kinase receptor Ret K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
B ROS family
C 659567 sev; proto-oncogene tyrosine-protein kinase ROS K05088 ROS1; proto-oncogene tyrosine-protein kinase ROS [EC:2.7.10.1]
B CCK family
C 660815 tyrosine-protein kinase-like otk K05127 PTK7; PTK7 protein tyrosine kinase 7 [EC:2.7.10.1]
B RYK family
C 658460 tyrosine-protein kinase Drl K05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]
B MUSK family
C 103313028 tyrosine-protein kinase transmembrane receptor Ror2 K05129 MUSK; muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1]
B LMR family [OT]
C 103313170 uncharacterized LOC103313170 K08898 LMTK2; lemur tyrosine kinase 2 [EC:2.7.10.1]
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ANon-receptor tyrosine kinases
B ABL family
C 657095 tyrosine-protein kinase Abl K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
B ACK family
C 659416 uncharacterized LOC659416 K08886 TNK2; activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1]
C 656701 activated CDC42 kinase 1 K08886 TNK2; activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1]
C 664095 tyrosine-protein kinase PR2 K08886 TNK2; activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1]
B CSK family
C 656886 tyrosine-protein kinase CSK K05728 CSK; c-src tyrosine kinase [EC:2.7.10.2]
B FAK family
C 664221 focal adhesion kinase 1 K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
B FES family
C 660208 tyrosine-protein kinase Fps85D K08889 FER; tyrosine-protein kinase Fer [EC:2.7.10.2]
B JAK family [OT]
C 663273 Hop; tyrosine-protein kinase hopscotch K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
B SRC family
C 657585 tyrosine-protein kinase Src42A K08892 FRK; fyn-related kinase [EC:2.7.10.2]
C 656565 tyrosine-protein kinase Src64B K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
B TEC family
C 663266 tyrosine-protein kinase Btk29A K07364 TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]
B SYK family
C 657609 tyrosine-protein kinase shark K17512 SHARK; tyrosine-protein kinase shark [EC:2.7.10.2]
B Other
B Bacterial
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AHistidine kinases
B OmpR family
B NarL family
B Spo family [OT]
B CitB family [OT]
B LytTR family [OT]
B NtrC family
B CheA family [OT]
B Cell cycle family [OT]
B Lux family [OT]
B LuxR family [OT]
B Other
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 2, 2024
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Classification taken and modified from Hanks (2003)