+F Repair protein KO
#
DNA Repair and Recombination Proteins - Trametes versicolor
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D TRAVEDRAFT_44861 uncharacterized protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E TRAVEDRAFT_149763 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E TRAVEDRAFT_137083 DNA glycosylase K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E TRAVEDRAFT_171246 DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E TRAVEDRAFT_153786 uncharacterized protein K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
E TRAVEDRAFT_118709 DNA glycosylase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E TRAVEDRAFT_60204 DNA glycosylase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E TRAVEDRAFT_19489 uncharacterized protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E TRAVEDRAFT_116703 AP endonuclease K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E TRAVEDRAFT_45617 uncharacterized protein K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E TRAVEDRAFT_167909 DNase I-like protein K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F TRAVEDRAFT_37590 delta DNA polymerase K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F TRAVEDRAFT_165502 DNA-directed DNA polymerase delta subunit POL31 K02328 POLD2; DNA polymerase delta subunit 2
F TRAVEDRAFT_44661 uncharacterized protein K03504 POLD3; DNA polymerase delta subunit 3
F TRAVEDRAFT_71842 uncharacterized protein K03505 POLD4; DNA polymerase delta subunit 4
E DNA polymerase epsilon complex
F TRAVEDRAFT_59949 DUF1744-domain-containing protein K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F TRAVEDRAFT_44844 epsilon DNA polymerase K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F TRAVEDRAFT_53064 uncharacterized protein K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F TRAVEDRAFT_122509 uncharacterized protein K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
E TRAVEDRAFT_77681 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E TRAVEDRAFT_175325 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E TRAVEDRAFT_60413 PIN domain-like protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E TRAVEDRAFT_71384 PIN domain-like protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E TRAVEDRAFT_139674 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
D Other BER factors
E TRAVEDRAFT_59509 phospholipase D/nuclease K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E TRAVEDRAFT_136817 DNA 5'-adenosine monophosphate hydrolase K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E TRAVEDRAFT_71011 PNK3P-domain-containing protein K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E TRAVEDRAFT_59518 uncharacterized protein K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E TRAVEDRAFT_140756 PARP-domain-containing protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E TRAVEDRAFT_68820 PARP-domain-containing protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F TRAVEDRAFT_71338 Rad4-domain-containing protein K10838 XPC; xeroderma pigmentosum group C-complementing protein
F TRAVEDRAFT_56121 UV excision repair protein Rad23 K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F TRAVEDRAFT_31548 RING/U-box K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F TRAVEDRAFT_26044 Cullin-domain-containing protein K10609 CUL4; cullin 4
F TRAVEDRAFT_167065 uncharacterized protein K10610 DDB1; DNA damage-binding protein 1
E NER4 complex
F TRAVEDRAFT_119621 RNI-like protein K15082 RAD7; DNA repair protein RAD7
F TRAVEDRAFT_144646 uncharacterized protein K15083 RAD16; DNA repair protein RAD16
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F TRAVEDRAFT_110086 beta and beta-prime subunits of DNA dependent RNA-polymerase K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F TRAVEDRAFT_33021 DNA-dependent RNA polymerase II second largest subunit K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F TRAVEDRAFT_17573 DNA-directed RNA polymerase II core subunit RPB3 K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F TRAVEDRAFT_71888 RNA polymerase II K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F TRAVEDRAFT_59082 DNA-directed RNA polymerase RPB5 subunit K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F TRAVEDRAFT_68046 RNA polymerase Rpb6 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F TRAVEDRAFT_167523 DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F TRAVEDRAFT_159392 RNA polymerase K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F TRAVEDRAFT_173922 DNA-directed RNA polymerase II core subunit RPB9 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F TRAVEDRAFT_40930 DNA-directed RNA polymerase core subunit RPB10 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F TRAVEDRAFT_31057 RBP11-like subunits of RNA polymerase K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F TRAVEDRAFT_27224 DNA-directed RNA polymerase core subunit RPC10 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F TRAVEDRAFT_31548 RING/U-box K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F TRAVEDRAFT_26044 Cullin-domain-containing protein K10609 CUL4; cullin 4
F TRAVEDRAFT_167065 uncharacterized protein K10610 DDB1; DNA damage-binding protein 1
E Other TCR factor
F TRAVEDRAFT_164368 Elf1-domain-containing protein K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E TRAVEDRAFT_169134 DNA helicase K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E TRAVEDRAFT_119749 DNA repair helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E TRAVEDRAFT_161612 TFIIH/NER complex subunit TFB1 K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E TRAVEDRAFT_55967 TFIIH basal transcription factor complex subunit SSL1 K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E TRAVEDRAFT_142083 transcription factor Tfb4 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E TRAVEDRAFT_126287 transcription factor Tfb2 K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E TRAVEDRAFT_50667 nucleotide excision repair TFIIH subunit K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E TRAVEDRAFT_129985 uncharacterized protein K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E TRAVEDRAFT_172147 nucleotide excision repair TFIIH subunit K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E TRAVEDRAFT_37523 CMGC/CDK/CDK7 protein kinase K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E TRAVEDRAFT_112086 cyclin-like protein K06634 CCNH; cyclin H
E TRAVEDRAFT_45450 CDK-activating kinase assembly factor K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E TRAVEDRAFT_27847 replication factor-a protein K07466 RFA1; replication factor A1
E TRAVEDRAFT_145653 replication protein A subunit RPA32 K10739 RFA2; replication factor A2
E TRAVEDRAFT_60456 replication factor A protein 3 K10740 RPA3; replication factor A3
D Other NER factors
E TRAVEDRAFT_158843 uncharacterized protein K10847 XPA; DNA-repair protein complementing XP-A cells
E TRAVEDRAFT_171645 DNA repair protein RAD10 K10849 ERCC1; DNA excision repair protein ERCC-1
E TRAVEDRAFT_72315 ssDNA endodeoxyribonuclease RAD1 K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E TRAVEDRAFT_72648 PIN domain-like protein K10846 ERCC5; DNA excision repair protein ERCC-5
E TRAVEDRAFT_139674 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E TRAVEDRAFT_148714 ARM repeat-containing protein K15075 MET18; DNA repair/transcription protein MET18/MMS19
E TRAVEDRAFT_150105 Cullin-domain-containing protein K03869 CUL3; cullin 3
E TRAVEDRAFT_129736 POZ domain-containing protein K03872 ELOC; elongin-C
E TRAVEDRAFT_136630 uncharacterized protein K15077 ELA1; elongin-A
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E TRAVEDRAFT_171157 DNA mismatch repair protein K08735 MSH2; DNA mismatch repair protein MSH2
E TRAVEDRAFT_57899 mismatch repair protein MSH3 K08736 MSH3; DNA mismatch repair protein MSH3
E TRAVEDRAFT_172942 DNA mismatch repair protein Msh6 K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E TRAVEDRAFT_38851 DNA mismatch repair protein MutL K08734 MLH1; DNA mismatch repair protein MLH1
E TRAVEDRAFT_59778 DNA mismatch repair protein MutL K10858 PMS2; DNA mismatch repair protein PMS2
E TRAVEDRAFT_163075 uncharacterized protein K08739 MLH3; DNA mismatch repair protein MLH3
D DNA polymerase delta complex
E TRAVEDRAFT_37590 delta DNA polymerase K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E TRAVEDRAFT_165502 DNA-directed DNA polymerase delta subunit POL31 K02328 POLD2; DNA polymerase delta subunit 2
E TRAVEDRAFT_44661 uncharacterized protein K03504 POLD3; DNA polymerase delta subunit 3
E TRAVEDRAFT_71842 uncharacterized protein K03505 POLD4; DNA polymerase delta subunit 4
D RPA (replication factor A)
E TRAVEDRAFT_27847 replication factor-a protein K07466 RFA1; replication factor A1
E TRAVEDRAFT_145653 replication protein A subunit RPA32 K10739 RFA2; replication factor A2
E TRAVEDRAFT_60456 replication factor A protein 3 K10740 RPA3; replication factor A3
D RFC (replication factor C)
E TRAVEDRAFT_70355 DNA replication factor C large subunit K10754 RFC1; replication factor C subunit 1
E TRAVEDRAFT_55182 P-loop containing nucleoside triphosphate hydrolase protein K10755 RFC2_4; replication factor C subunit 2/4
E TRAVEDRAFT_165448 replication factor C K10755 RFC2_4; replication factor C subunit 2/4
E TRAVEDRAFT_72517 P-loop containing nucleoside triphosphate hydrolase protein K10756 RFC3_5; replication factor C subunit 3/5
E TRAVEDRAFT_168084 P-loop containing nucleoside triphosphate hydrolase protein K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E TRAVEDRAFT_77681 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E TRAVEDRAFT_175325 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E TRAVEDRAFT_39409 PIN domain-like protein K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E TRAVEDRAFT_139674 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E TRAVEDRAFT_164476 WD40 repeat-like protein K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E TRAVEDRAFT_40214 DNA repair exonuclease K10865 MRE11; double-strand break repair protein MRE11
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
E TRAVEDRAFT_40214 DNA repair exonuclease K10865 MRE11; double-strand break repair protein MRE11
D BRCA complex
E TRAVEDRAFT_109911 uncharacterized protein K08775 BRCA2; breast cancer 2 susceptibility protein
D RecA family proteins
E TRAVEDRAFT_51134 P-loop containing nucleoside triphosphate hydrolase protein K10870 RAD51L2; RAD51-like protein 2
E TRAVEDRAFT_126168 P-loop containing nucleoside triphosphate hydrolase protein K10871 RAD51L3; RAD51-like protein 3
E TRAVEDRAFT_41847 uncharacterized protein K10879 XRCC2; DNA-repair protein XRCC2
E TRAVEDRAFT_146091 uncharacterized protein K10880 XRCC3; DNA-repair protein XRCC3
D Rad52 family proteins
E TRAVEDRAFT_130753 uncharacterized protein K10873 RAD52; DNA repair and recombination protein RAD52
D Rad54 family proteins
E TRAVEDRAFT_36048 DNA repair protein SNF2 family K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E TRAVEDRAFT_57102 uncharacterized protein K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E TRAVEDRAFT_176173 ATP-dependent DNA helicase K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E TRAVEDRAFT_112523 prokaryotic type I DNA topoisomerase K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
D RPA (replication factor A)
E TRAVEDRAFT_27847 replication factor-a protein K07466 RFA1; replication factor A1
E TRAVEDRAFT_145653 replication protein A subunit RPA32 K10739 RFA2; replication factor A2
E TRAVEDRAFT_60456 replication factor A protein 3 K10740 RPA3; replication factor A3
D Protein phosphatase 4
E TRAVEDRAFT_142675 serine/threonine protein phosphatase K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E TRAVEDRAFT_57430 ARM repeat-containing protein K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E TRAVEDRAFT_40842 PPP4R2-domain-containing protein K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E TRAVEDRAFT_118082 DUF625-domain-containing protein K17491 SMEK; protein phosphatase 4 regulatory subunit 3
D AP-5 complex
D SMC5-SMC6 complex
E TRAVEDRAFT_143374 P-loop containing nucleoside triphosphate hydrolase protein K22803 SMC5; structural maintenance of chromosomes protein 5
E TRAVEDRAFT_71253 P-loop containing nucleoside triphosphate hydrolase protein K22804 SMC6; structural maintenance of chromosomes protein 6
E TRAVEDRAFT_166941 SUMO ligase MMS21 K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E TRAVEDRAFT_134999 Smc5-Smc6 complex subunit NSE4 K22825 NSMCE4; non-structural maintenance of chromosomes element 4
D Other HR factors
E TRAVEDRAFT_72490 proteasome regulatory particle lid subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E TRAVEDRAFT_41251 uncharacterized protein K10991 SWI5; DNA repair protein Swi5/Sae3
E TRAVEDRAFT_136355 endonuclease K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E TRAVEDRAFT_68878 uncharacterized protein K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E TRAVEDRAFT_54434 uncharacterized protein K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E TRAVEDRAFT_73115 uncharacterized protein K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E TRAVEDRAFT_31887 MRG-domain-containing protein K11339 MORF4L1; mortality factor 4-like protein 1
E TRAVEDRAFT_63656 HD-domain/PDEase-like protein K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E TRAVEDRAFT_34638 uncharacterized protein K25770 ZSWIM7; zinc finger SWIM domain-containing protein 7
E TRAVEDRAFT_25296 WLM-domain-containing protein K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
E TRAVEDRAFT_38022 WLM-domain-containing protein K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
E TRAVEDRAFT_111006 P-loop containing nucleoside triphosphate hydrolase protein K14635 MPH1; ATP-dependent DNA helicase MPH1 [EC:5.6.2.4]
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E TRAVEDRAFT_170005 ku70-like protein K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E TRAVEDRAFT_140656 SPOC domain-like protein K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
D MRX complex
E TRAVEDRAFT_40214 DNA repair exonuclease K10865 MRE11; double-strand break repair protein MRE11
D DNA Ligase 4 complex
E TRAVEDRAFT_64949 DNA ligase 4 K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
E TRAVEDRAFT_124375 uncharacterized protein K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
D X-family DNA polymerases
E TRAVEDRAFT_59518 uncharacterized protein K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E TRAVEDRAFT_51714 Nucleotidyltransferase K10981 POL4; DNA polymerase IV [EC:2.7.7.7]
E TRAVEDRAFT_51711 Nucleotidyltransferase K10981 POL4; DNA polymerase IV [EC:2.7.7.7]
D Other NHEJ factors
E TRAVEDRAFT_136817 DNA 5'-adenosine monophosphate hydrolase K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E TRAVEDRAFT_36726 uncharacterized protein K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
E TRAVEDRAFT_51151 uncharacterized protein K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E TRAVEDRAFT_169396 uncharacterized protein K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
E TRAVEDRAFT_112523 prokaryotic type I DNA topoisomerase K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
D FANCD2-I complex
D Downstream FA components
E TRAVEDRAFT_109911 uncharacterized protein K08775 BRCA2; breast cancer 2 susceptibility protein
D Other FA pathway factors
E TRAVEDRAFT_70630 uncharacterized protein K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E TRAVEDRAFT_51134 P-loop containing nucleoside triphosphate hydrolase protein K10870 RAD51L2; RAD51-like protein 2
E TRAVEDRAFT_165540 telomeric DNA binding protein K11137 TELO2; telomere length regulation protein
E TRAVEDRAFT_32004 uncharacterized protein K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
E TRAVEDRAFT_49793 Metallo-dependent phosphatase K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
D Ubiquitin ligases
D Others
E TRAVEDRAFT_170197 uncharacterized protein K23314 WRAP53; telomerase Cajal body protein 1
E TRAVEDRAFT_111867 transcription factor K24752 WDR70; WD repeat-containing protein 70
E TRAVEDRAFT_164476 WD40 repeat-like protein K24755 WDR76; WD repeat-containing protein 76
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D TRAVEDRAFT_59319 DNA/RNA polymerase K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D TRAVEDRAFT_34641 DNA/RNA polymerase K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D TRAVEDRAFT_64247 deoxycytidyl transferase K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D TRAVEDRAFT_42080 DNA-directed DNA polymerase K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
C Rad6 epistasis group
D TRAVEDRAFT_174569 ubiquitin-conjugating enzyme K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D TRAVEDRAFT_46061 E3 ubiquitin-protein ligase RAD18 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D TRAVEDRAFT_157721 uncharacterized protein K15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]
D TRAVEDRAFT_56219 uncharacterized protein K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D TRAVEDRAFT_33062 uncharacterized protein K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D TRAVEDRAFT_72002 UBC-like protein K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D TRAVEDRAFT_30645 ubiquitin-conjugating enzyme K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D TRAVEDRAFT_77681 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D TRAVEDRAFT_175325 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D TRAVEDRAFT_62357 uncharacterized protein K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D TRAVEDRAFT_167684 uncharacterized protein K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D TRAVEDRAFT_109577 cell cycle checkpoint K10903 HUS1; HUS1 checkpoint protein
D TRAVEDRAFT_46094 uncharacterized protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
D TRAVEDRAFT_165927 Rad1-domain-containing protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D TRAVEDRAFT_152598 Rad17-domain-containing protein K06662 HRAD17; cell cycle checkpoint protein
D TRAVEDRAFT_55182 P-loop containing nucleoside triphosphate hydrolase protein K10755 RFC2_4; replication factor C subunit 2/4
D TRAVEDRAFT_165448 replication factor C K10755 RFC2_4; replication factor C subunit 2/4
D TRAVEDRAFT_72517 P-loop containing nucleoside triphosphate hydrolase protein K10756 RFC3_5; replication factor C subunit 3/5
D TRAVEDRAFT_168084 P-loop containing nucleoside triphosphate hydrolase protein K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D TRAVEDRAFT_46094 uncharacterized protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
D TRAVEDRAFT_165927 Rad1-domain-containing protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D TRAVEDRAFT_67497 timeless-domain-containing protein K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D TRAVEDRAFT_61454 Swi3-domain-containing protein K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
D TRAVEDRAFT_63127 uncharacterized protein K11272 MRC1; mediator of replication checkpoint protein 1
C Triple T complex
D TRAVEDRAFT_165540 telomeric DNA binding protein K11137 TELO2; telomere length regulation protein
D TRAVEDRAFT_55299 uncharacterized protein K20403 TTI1; TELO2-interacting protein 1
C BAG6-UBL4A-GET4 complex
D TRAVEDRAFT_130603 ubiquitin-domain-containing protein K23388 UBL4; ubiquitin-like protein 4
D TRAVEDRAFT_29572 uncharacterized protein K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D TRAVEDRAFT_162993 uncharacterized protein K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D TRAVEDRAFT_148287 uncharacterized protein K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D TRAVEDRAFT_66216 CAMK/CAMKL/CHK1 protein kinase K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D TRAVEDRAFT_57888 uncharacterized protein K02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]
D TRAVEDRAFT_162598 14-3-3-like protein K06630 YWHAE; 14-3-3 protein epsilon
D TRAVEDRAFT_27130 14-3-3 K06630 YWHAE; 14-3-3 protein epsilon
D TRAVEDRAFT_17922 kinase-like protein K02831 RAD53; ser/thr/tyr protein kinase RAD53 [EC:2.7.11.-]
D TRAVEDRAFT_34695 kinase-like protein K02831 RAD53; ser/thr/tyr protein kinase RAD53 [EC:2.7.11.-]
D TRAVEDRAFT_113607 Pkinase-domain-containing protein K02831 RAD53; ser/thr/tyr protein kinase RAD53 [EC:2.7.11.-]
D TRAVEDRAFT_69566 kinase-like protein K02831 RAD53; ser/thr/tyr protein kinase RAD53 [EC:2.7.11.-]
D TRAVEDRAFT_69567 kinase-like protein K02831 RAD53; ser/thr/tyr protein kinase RAD53 [EC:2.7.11.-]
D TRAVEDRAFT_69569 kinase-like protein K02831 RAD53; ser/thr/tyr protein kinase RAD53 [EC:2.7.11.-]
D TRAVEDRAFT_69563 uncharacterized protein K20780 MDC1; mediator of DNA damage checkpoint protein 1
D TRAVEDRAFT_141457 uncharacterized protein K03114 SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]
D TRAVEDRAFT_26086 AAA-domain-containing protein K12196 VPS4; vacuolar protein-sorting-associated protein 4
D TRAVEDRAFT_169747 uncharacterized protein K25059 SDE2; replication stress response regulator SDE2
B Other factors with a suspected DNA repair function
C DNA polymerases
D TRAVEDRAFT_57898 DNA-directed DNA polymerase K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
C Nucleases
D TRAVEDRAFT_123535 DRMBL-domain-containing protein K15340 DCLRE1A; DNA cross-link repair 1A protein
D TRAVEDRAFT_58347 uncharacterized protein K17815 EXO5; exonuclease V [EC:3.1.-.-]
D TRAVEDRAFT_71603 uncharacterized protein K17815 EXO5; exonuclease V [EC:3.1.-.-]
D TRAVEDRAFT_135462 nuclease Le1 K05986 NUCS; nuclease S1 [EC:3.1.30.1]
D TRAVEDRAFT_30333 phospholipase C/P1 nuclease K05986 NUCS; nuclease S1 [EC:3.1.30.1]
C Helicases
D TRAVEDRAFT_128513 uncharacterized protein K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]
C PSO4 complex
D TRAVEDRAFT_68627 nuclear matrix protein NMP200 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D TRAVEDRAFT_64114 Cc.Cdc5 protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D TRAVEDRAFT_25927 breast carcinoma amplified sequence 2 K12861 BCAS2; pre-mRNA-splicing factor SPF27
D TRAVEDRAFT_61069 WD40 repeat-like protein K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D TRAVEDRAFT_143884 dUTP pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D TRAVEDRAFT_28460 uncharacterized protein K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D TRAVEDRAFT_41085 alpha subunit of ribonucleoside diphosphate reductase K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D TRAVEDRAFT_137477 putative ribonucleoside-diphosphate reductase small chain B K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
D TRAVEDRAFT_69658 ribonucleotide reductase small subunit K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
D TRAVEDRAFT_63110 uncharacterized protein K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D TRAVEDRAFT_44861 uncharacterized protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E TRAVEDRAFT_149763 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E TRAVEDRAFT_113464 DNA glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E TRAVEDRAFT_113342 DNA glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E TRAVEDRAFT_112494 DNA glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E TRAVEDRAFT_112665 DNA glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E TRAVEDRAFT_112622 DNA glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E TRAVEDRAFT_171246 DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E TRAVEDRAFT_42423 AtMMH-1 K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E TRAVEDRAFT_60204 DNA glycosylase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E TRAVEDRAFT_19489 uncharacterized protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E TRAVEDRAFT_37935 UvrD-helicase-domain-containing protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E TRAVEDRAFT_37935 UvrD-helicase-domain-containing protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D TRAVEDRAFT_143884 dUTP pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024