+D GENES KO
#
KEGG Orthology (KO) - Tropheryma whipplei Twist
%
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A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:twh00010]
D TWT_213 glkA; glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D TWT_342 gpi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D TWT_302 tpi; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D TWT_300 gap; glyceraldehyde 3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D TWT_301 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D TWT_655 gpm; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D TWT_783 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D TWT_290 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D TWT_255 aceE; pyruvate dehydrogenase E1 component K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1]
D TWT_503 sucB; dihydrolipoamide succinyltransferase component E2 K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D TWT_502 lpd; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00020 Citrate cycle (TCA cycle) [PATH:twh00020]
D TWT_502 lpd; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D TWT_630 pca; pyruvate carboxylase K01958 PC; pyruvate carboxylase [EC:6.4.1.1]
D TWT_255 aceE; pyruvate dehydrogenase E1 component K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1]
D TWT_503 sucB; dihydrolipoamide succinyltransferase component E2 K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
C 00030 Pentose phosphate pathway [PATH:twh00030]
D TWT_342 gpi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D TWT_343 zwf; glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
D TWT_308 devB; 6-phosphogluconolactonase K01057 PGLS; 6-phosphogluconolactonase [EC:3.1.1.31]
D TWT_492 gnd; 6-phosphogluconate dehydrogenase K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
D TWT_357 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D TWT_340 tkt; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D TWT_341 tal; transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D TWT_397 rpi; ribose 5-phosphate isomerase B K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D TWT_187 prsA; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D TWT_646 kdgK; 2-keto-3-deoxygluconate kinase K00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45]
C 00040 Pentose and glucuronate interconversions [PATH:twh00040]
D TWT_649 hexulose-6-phosphate synthase K03078 ulaD; 3-dehydro-L-gulonate-6-phosphate decarboxylase [EC:4.1.1.85]
D TWT_648 sgaU; hexulose-6-phosphate isomerase K03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22]
D TWT_647 araD; L-ribulose-5-phosphate 4-epimerase K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4]
D TWT_357 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
C 00051 Fructose and mannose metabolism [PATH:twh00051]
D TWT_122 manA; mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]
D TWT_017 pmmB; phosphomannomutase K01840 manB; phosphomannomutase [EC:5.4.2.8]
D TWT_127 pmmA; phosphomannomutase K01840 manB; phosphomannomutase [EC:5.4.2.8]
D TWT_356 manC; Mannose-1-phosphate guanylyltransferase K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D TWT_302 tpi; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D TWT_397 rpi; ribose 5-phosphate isomerase B K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
C 00052 Galactose metabolism
D TWT_213 glkA; glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
C 00053 Ascorbate and aldarate metabolism [PATH:twh00053]
D TWT_649 hexulose-6-phosphate synthase K03078 ulaD; 3-dehydro-L-gulonate-6-phosphate decarboxylase [EC:4.1.1.85]
D TWT_648 sgaU; hexulose-6-phosphate isomerase K03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22]
D TWT_647 araD; L-ribulose-5-phosphate 4-epimerase K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4]
C 00500 Starch and sucrose metabolism [PATH:twh00500]
D TWT_213 glkA; glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D TWT_342 gpi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:twh00520]
D TWT_606 glmS; glucosamine--fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D TWT_146 mrsA; phosphohexose mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10]
D TWT_188 putative UDP-N-acetylglucosamine pyrophosphorylase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
D TWT_508 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D TWT_718 murB; UDP-N-acetylmuramate dehydrogenase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D TWT_213 glkA; glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D TWT_342 gpi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D TWT_122 manA; mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]
D TWT_017 pmmB; phosphomannomutase K01840 manB; phosphomannomutase [EC:5.4.2.8]
D TWT_127 pmmA; phosphomannomutase K01840 manB; phosphomannomutase [EC:5.4.2.8]
D TWT_356 manC; Mannose-1-phosphate guanylyltransferase K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
C 00620 Pyruvate metabolism [PATH:twh00620]
D TWT_255 aceE; pyruvate dehydrogenase E1 component K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1]
D TWT_503 sucB; dihydrolipoamide succinyltransferase component E2 K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D TWT_502 lpd; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D TWT_290 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D TWT_020 bccA; biotin carboxylase K11263 bccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
D TWT_630 pca; pyruvate carboxylase K01958 PC; pyruvate carboxylase [EC:6.4.1.1]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:twh00630]
D TWT_020 bccA; biotin carboxylase K11263 bccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
D TWT_770 predicted phosphatase, HAD family K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]
D TWT_261 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D TWT_635 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D TWT_135 gcvB; glycine dehydrogenase K00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]
D TWT_638 gcvT; aminomethyltransferase K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D TWT_502 lpd; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D TWT_637 gcvH; glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
C 00640 Propanoate metabolism [PATH:twh00640]
D TWT_790 pdhA; pyruvate dehydrogenase E1 component alpha subunit K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
D TWT_789 pdhB; pyruvate dehydrogenase E1 component beta subunit K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4]
D TWT_788 pdhC; dihydrolipoamide acetyltransferase K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168]
D TWT_502 lpd; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D TWT_020 bccA; biotin carboxylase K11263 bccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
D TWT_633 gabT; 4-aminobutyrate aminotransferase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
C 00650 Butanoate metabolism [PATH:twh00650]
D TWT_633 gabT; 4-aminobutyrate aminotransferase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D TWT_326 adh; zinc-type alcohol dehydrogenase K18369 adh2; alcohol dehydrogenase [EC:1.1.1.-]
D TWT_205 ilvB; acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D TWT_206 ilvH; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
C 00660 C5-Branched dibasic acid metabolism
D TWT_205 ilvB; acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D TWT_206 ilvH; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
C 00562 Inositol phosphate metabolism
D TWT_302 tpi; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:twh00190]
D TWT_780 ndh; NADH dehydrogenase K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]
D TWT_248 qcrA; ubiquinol-cytochrome c reductase iron-sulfur subunit K03890 qcrA; quinol---cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
D TWT_249 qcrB; ubiquinol-cytochrome c reductase cytochrome b subunit K03891 qcrB; quinol---cytochrome-c reductase cytochrome b subunit [EC:7.1.1.8]
D TWT_247 qcrC; ubiquinol-cytochrome c reductase cytochrome c subunit K03889 qcrC; quinol---cytochrome-c reductase cytochrome c subunit [EC:7.1.1.8]
D TWT_339 ctaB; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D TWT_246 ctaE; cytochrome c oxidase subunit III K02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9]
D TWT_244 ctaD; cytochrome c oxidase subunit I K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D TWT_243 ctaC; cytochrome c oxidase subunit II K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D TWT_338 ctaA; cytochrome AA3 controlling prrotein K02259 COX15; heme a synthase [EC:1.17.99.9]
D TWT_426 atpA; ATP synthase alpha chain K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D TWT_424 atpD; ATP synthase beta chain K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D TWT_425 atpG; ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D TWT_427 atpH; ATP synthase delta chain K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D TWT_423 atpC; ATP synthase epsilon chain K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D TWT_430 atpB; ATP synthase A chain K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D TWT_428 atpF; ATP synthase B chain K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D TWT_429 atpE; ATP synthase C chain K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D TWT_307 ppa; inorganic pyrophosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
D TWT_154 ppa; inorganic pyrophosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation in photosynthetic organisms
C 00720 Carbon fixation pathways in prokaryotes
C 00680 Methane metabolism [PATH:twh00680]
D TWT_635 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D TWT_783 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D TWT_655 gpm; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
C 00910 Nitrogen metabolism
D TWT_261 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
C 00920 Sulfur metabolism
D TWT_390 sseA; thiosulfate sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis [PATH:twh00061]
D TWT_020 bccA; biotin carboxylase K11263 bccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
D TWT_252 acp; acyl carrier protein K02078 acpP; acyl carrier protein
D TWT_254 fabD; malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D TWT_253 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D TWT_251 kasA; 3-oxoacyl-[acyl-carrier-protein] synthase K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D TWT_313 fabG; 3-oxoacyl-[acyl-carrier protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation
C 00073 Cutin, suberine and wax biosynthesis
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism
D TWT_214 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
C 00564 Glycerophospholipid metabolism [PATH:twh00564]
D TWT_506 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]
D TWT_214 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D TWT_445 cdsA; phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41]
D TWT_612 pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K00995 pgsA; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]
D TWT_064 cls; cardiolipin synthetase K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-]
C 00565 Ether lipid metabolism
C 00600 Sphingolipid metabolism
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism
C 01040 Biosynthesis of unsaturated fatty acids
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:twh00230]
D TWT_187 prsA; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D TWT_723 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D TWT_725 purD; phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]
D TWT_083 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D TWT_794 purL; phosphoribosylformylglycinamidine synthase II K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3]
D TWT_796 unknown K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3]
D TWT_795 purQ; phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D TWT_724 purM; phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D TWT_026 purK; phosphoribosylaminoimidazole carboxylase ATPase subunit K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]
D TWT_027 purE; phosphoribosylaminoimidazole carboxylase catalytic subunit K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D TWT_791 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D TWT_084 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D TWT_742 sugar phosphatase K02566 nagD; 5'-nucleotidase [EC:3.1.3.5]
D TWT_018 deoD; purine nucleoside phosphorylase K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1]
D TWT_589 hpt; hypoxanthine-guanine phosphoribosyltransferase K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]
D TWT_075 guaB1; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D TWT_076 guaB2; inosine-5'-monophosphate dehydrogenase-like protein K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D TWT_475 ndkA; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D TWT_621 unknown K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
D TWT_079 guaA; GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D TWT_363 gmk; guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8]
D TWT_683 nrdA; ribonucleotide reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D TWT_682 nrdB; ribonucleotide reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D TWT_287 dgt; dGTP triphosphohydrolase K01129 dgt; dGTPase [EC:3.1.5.1]
D TWT_275 relA; GTP pyrophosphokinase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
D TWT_792 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D TWT_534 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D TWT_263 unknown K19710 E2.7.7.53; ATP adenylyltransferase [EC:2.7.7.53]
C 00240 Pyrimidine metabolism [PATH:twh00240]
D TWT_365 carB; carbamoyl-phosphate synthase large chain K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D TWT_366 carA; carbamoyl-phosphate synthase small chain K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D TWT_196 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D TWT_367 pyrC; dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3]
D TWT_238 pyrD; dihydroorotate oxidase K00254 DHODH; dihydroorotate dehydrogenase [EC:1.3.5.2]
D TWT_743 umpA; orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D TWT_364 pyrF; orotidine-5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D TWT_447 pyrH; uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D TWT_475 ndkA; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D TWT_100 pyrG; CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2]
D TWT_742 sugar phosphatase K02566 nagD; 5'-nucleotidase [EC:3.1.3.5]
D TWT_787 dcd; dCTP deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13]
D TWT_683 nrdA; ribonucleotide reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D TWT_682 nrdB; ribonucleotide reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D TWT_695 tmk; thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D TWT_487 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D TWT_616 thyX; thymidylate synthase K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:twh00250]
D TWT_792 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D TWT_791 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D TWT_196 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D TWT_633 gabT; 4-aminobutyrate aminotransferase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D TWT_261 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D TWT_365 carB; carbamoyl-phosphate synthase large chain K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D TWT_366 carA; carbamoyl-phosphate synthase small chain K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D TWT_795 purQ; phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D TWT_606 glmS; glucosamine--fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D TWT_723 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C 00260 Glycine, serine and threonine metabolism [PATH:twh00260]
D TWT_708 ask; aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D TWT_707 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D TWT_439 thrA; homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D TWT_437 thrB; homoserine kinase K00872 thrB; homoserine kinase [EC:2.7.1.39]
D TWT_438 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D TWT_635 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D TWT_655 gpm; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D TWT_135 gcvB; glycine dehydrogenase K00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]
D TWT_638 gcvT; aminomethyltransferase K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D TWT_502 lpd; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D TWT_637 gcvH; glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D TWT_681 ilvA; threonine deaminase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
C 00270 Cysteine and methionine metabolism [PATH:twh00270]
D TWT_162 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D TWT_360 metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D TWT_708 ask; aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D TWT_707 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D TWT_439 thrA; homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D TWT_208 ilvE; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D TWT_390 sseA; thiosulfate sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
C 00280 Valine, leucine and isoleucine degradation [PATH:twh00280]
D TWT_208 ilvE; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D TWT_790 pdhA; pyruvate dehydrogenase E1 component alpha subunit K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
D TWT_789 pdhB; pyruvate dehydrogenase E1 component beta subunit K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4]
D TWT_788 pdhC; dihydrolipoamide acetyltransferase K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168]
D TWT_502 lpd; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D TWT_020 bccA; biotin carboxylase K11263 bccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
D TWT_633 gabT; 4-aminobutyrate aminotransferase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
C 00290 Valine, leucine and isoleucine biosynthesis [PATH:twh00290]
D TWT_681 ilvA; threonine deaminase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D TWT_205 ilvB; acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D TWT_206 ilvH; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D TWT_207 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D TWT_204 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D TWT_208 ilvE; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
C 00300 Lysine biosynthesis [PATH:twh00300]
D TWT_439 thrA; homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D TWT_708 ask; aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D TWT_707 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D TWT_225 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D TWT_223 murF; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
C 00310 Lysine degradation [PATH:twh00310]
D TWT_502 lpd; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D TWT_633 gabT; 4-aminobutyrate aminotransferase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
C 00220 Arginine biosynthesis [PATH:twh00220]
D TWT_795 purQ; phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D TWT_261 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
C 00330 Arginine and proline metabolism [PATH:twh00330]
D TWT_752 proC; pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]
C 00340 Histidine metabolism
C 00350 Tyrosine metabolism
C 00360 Phenylalanine metabolism [PATH:twh00360]
D TWT_335 dioxygenase ferredoxin subunit K05710 hcaC; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin component
C 00380 Tryptophan metabolism
D TWT_502 lpd; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:twh00400]
D TWT_215 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
D TWT_370 aroB; 3-dehydroquinate synthase K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4]
D TWT_369 aroD; 3-dehydroquinate dehydratase K03786 aroQ; 3-dehydroquinate dehydratase II [EC:4.2.1.10]
D TWT_371 aroK; shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71]
D TWT_567 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D TWT_372 aroF; chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5]
D TWT_386 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D TWT_793 putative chorismate mutase protein K04092 tyrA1; chorismate mutase [EC:5.4.99.5]
D TWT_050 tyrA; prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism [PATH:twh00410]
D TWT_633 gabT; 4-aminobutyrate aminotransferase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D TWT_063 panC; pantoate--beta-alanine ligase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]
C 00430 Taurine and hypotaurine metabolism
C 00440 Phosphonate and phosphinate metabolism
C 00450 Selenocompound metabolism [PATH:twh00450]
D TWT_162 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D TWT_763 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism
D TWT_635 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 00470 D-Amino acid metabolism [PATH:twh00470]
D TWT_495 alanine racemase-like protein K01775 alr; alanine racemase [EC:5.1.1.1]
D TWT_496 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D TWT_505 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D TWT_795 purQ; phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D TWT_226 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
C 00480 Glutathione metabolism [PATH:twh00480]
D TWT_501 pepB; aminopeptidase A/I K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D TWT_399 pepD; aminopeptidase K01256 pepN; aminopeptidase N [EC:3.4.11.2]
D TWT_492 gnd; 6-phosphogluconate dehydrogenase K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
D TWT_343 zwf; glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
B
B 09107 Glycan biosynthesis and metabolism
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis [PATH:twh00515]
D TWT_121 unknown K00728 POMT; dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109]
C 00514 Other types of O-glycan biosynthesis [PATH:twh00514]
D TWT_121 unknown K00728 POMT; dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109]
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
C 00540 Lipopolysaccharide biosynthesis
C 00542 O-Antigen repeat unit biosynthesis
C 00541 O-Antigen nucleotide sugar biosynthesis [PATH:twh00541]
D TWT_032 rmlA; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D TWT_030 rmlB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D TWT_031 rmlC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D TWT_029 rmlD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
D TWT_122 manA; mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]
D TWT_017 pmmB; phosphomannomutase K01840 manB; phosphomannomutase [EC:5.4.2.8]
D TWT_127 pmmA; phosphomannomutase K01840 manB; phosphomannomutase [EC:5.4.2.8]
D TWT_356 manC; Mannose-1-phosphate guanylyltransferase K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D TWT_188 putative UDP-N-acetylglucosamine pyrophosphorylase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
C 00550 Peptidoglycan biosynthesis [PATH:twh00550]
D TWT_508 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D TWT_718 murB; UDP-N-acetylmuramate dehydrogenase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D TWT_229 murC; UDP-N-acetylmuramate--alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D TWT_226 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D TWT_225 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D TWT_505 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D TWT_223 murF; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D TWT_286 uppS; undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D TWT_315 undecaprenol kinase-like protein K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D TWT_224 murX; phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D TWT_228 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D TWT_222 pbpB; penicillin-binding protein 2 K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D TWT_776 pbpA; penicillin-binding protein K05364 pbpA; penicillin-binding protein A
D TWT_327 dacB; serine-type D-Ala-D-Ala carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D TWT_498 UDP-N-acetylmuramyl tripeptide synthase-like protein K23393 murT; lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13]
C 00552 Teichoic acid biosynthesis [PATH:twh00552]
D TWT_315 undecaprenol kinase-like protein K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:twh00730]
D TWT_416 cysteine desulfurase NifS-like protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D TWT_484 1-deoxyxylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]
D TWT_008 unknown K00949 thiN; thiamine pyrophosphokinase [EC:2.7.6.2]
D TWT_534 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00740 Riboflavin metabolism [PATH:twh00740]
D TWT_690 dipeptide ABC transporter substrate-binding-like protein K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]
D TWT_687 ribG; diaminohydroxyphosphoribosylaminopyrimidine deaminase K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
D TWT_689 dipeptide ABC transporter substrate-binding-like protein K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12]
D TWT_691 ribH; riboflavin synthase beta chain K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
D TWT_688 ribC; riboflavin synthase alpha chain K00793 ribE; riboflavin synthase [EC:2.5.1.9]
D TWT_581 ribF; riboflavin kinase K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]
C 00750 Vitamin B6 metabolism [PATH:twh00750]
D TWT_438 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D TWT_264 pyridoxine biosynthesis enzyme-like protein K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6]
D TWT_265 amidotransferase K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6]
C 00760 Nicotinate and nicotinamide metabolism [PATH:twh00760]
D TWT_623 unknown K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]
D TWT_018 deoD; purine nucleoside phosphorylase K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1]
D TWT_742 sugar phosphatase K02566 nagD; 5'-nucleotidase [EC:3.1.3.5]
D TWT_469 nadD; nicotinate-nucleotide adenylyltransferase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]
D TWT_405 nadE; NH(3)-dependent NAD(+) synthetase K01916 nadE; NAD+ synthase [EC:6.3.1.5]
D TWT_692 pncA; pyrazinamidase K08281 pncA; nicotinamidase/pyrazinamidase [EC:3.5.1.19 3.5.1.-]
D TWT_103 inorganic polyphosphate/ATP-NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
C 00770 Pantothenate and CoA biosynthesis [PATH:twh00770]
D TWT_205 ilvB; acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D TWT_206 ilvH; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D TWT_207 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D TWT_204 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D TWT_260 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]
D TWT_063 panC; pantoate--beta-alanine ligase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]
D TWT_147 coaA; pantothenate kinase K00867 coaA; type I pantothenate kinase [EC:2.7.1.33]
D TWT_361 dfp; flavoprotein K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]
D TWT_565 pantetheine-phosphate adenylyltransferase K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
D TWT_294 coaE; dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24]
D TWT_208 ilvE; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
C 00780 Biotin metabolism [PATH:twh00780]
D TWT_251 kasA; 3-oxoacyl-[acyl-carrier-protein] synthase K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D TWT_313 fabG; 3-oxoacyl-[acyl-carrier protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D TWT_024 birA; biotin acetyl-CoA carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C 00785 Lipoic acid metabolism [PATH:twh00785]
D TWT_463 lipB; lipoate-protein ligase B K03801 lipB; lipoyl(octanoyl) transferase [EC:2.3.1.181]
D TWT_464 lipA; lipoic acid synthase K03644 lipA; lipoyl synthase [EC:2.8.1.8]
D TWT_502 lpd; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D TWT_255 aceE; pyruvate dehydrogenase E1 component K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1]
D TWT_503 sucB; dihydrolipoamide succinyltransferase component E2 K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D TWT_790 pdhA; pyruvate dehydrogenase E1 component alpha subunit K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
D TWT_789 pdhB; pyruvate dehydrogenase E1 component beta subunit K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4]
D TWT_788 pdhC; dihydrolipoamide acetyltransferase K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168]
D TWT_135 gcvB; glycine dehydrogenase K00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]
D TWT_638 gcvT; aminomethyltransferase K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D TWT_637 gcvH; glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
C 00790 Folate biosynthesis [PATH:twh00790]
D TWT_587 folE; GTP cyclohydrolase I K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]
D TWT_586 folPXK; dihydropteroate synthase/dihydroneopterin aldolase/2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase fusion protein K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
D TWT_476 folC; folylpolyglutamate synthase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
D TWT_690 dipeptide ABC transporter substrate-binding-like protein K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]
D TWT_011 pabA; para-aminobenzoate synthetase component II K01664 pabA; para-aminobenzoate synthetase component II [EC:2.6.1.85]
D TWT_533 aminotransferase K02619 pabC; 4-amino-4-deoxychorismate lyase [EC:4.1.3.38]
C 00670 One carbon pool by folate [PATH:twh00670]
D TWT_634 folD; methylenetetrahydrofolate dehydrogenase NADP+ K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D TWT_635 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D TWT_083 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D TWT_084 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D TWT_358 fmt; methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D TWT_638 gcvT; aminomethyltransferase K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D TWT_616 thyX; thymidylate synthase K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]
D TWT_667 unknown K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism [PATH:twh00860]
D TWT_209 gltS; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D TWT_736 hemA; glutamyl-tRNA reductase (GLUTR) K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]
D TWT_729 hemL; glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D TWT_730 hemB; porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D TWT_732 hemC; porphobilinogen deaminase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D TWT_731 uroporphyrinogen-III synthase-like protein K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75]
D TWT_735 hemE; uroporphyrinogen decarboxylase K01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37]
D TWT_733 hemZ; ferrochelatase K01772 hemH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9]
D TWT_339 ctaB; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D TWT_338 ctaA; cytochrome AA3 controlling prrotein K02259 COX15; heme a synthase [EC:1.17.99.9]
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:twh00130]
D TWT_053 ubiE; ubiquinone/menaquinone biosynthesis methyltransferase K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201]
D TWT_052 menF; isochorismate synthase K02552 menF; menaquinone-specific isochorismate synthase [EC:5.4.4.2]
D TWT_068 menD; 2-oxoglutarate decarboxylase K02551 menD; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:2.2.1.9]
D TWT_737 menC; O-succinylbenzoate-CoA synthase K02549 menC; o-succinylbenzoate synthase [EC:4.2.1.113]
D TWT_111 menE; O-succinylbenzoic acid-CoA ligase K01911 menE; o-succinylbenzoate---CoA ligase [EC:6.2.1.26]
D TWT_110 menB; naphthoate synthase K01661 menB; naphthoate synthase [EC:4.1.3.36]
D TWT_070 menA; 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:twh00900]
D TWT_484 1-deoxyxylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]
D TWT_089 dxr; 1-deoxy-D-xylulose 5-phosphate reductoisomerase K00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]
D TWT_348 ispDF; IspD K12506 ispDF; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase / 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:2.7.7.60 4.6.1.12]
D TWT_605 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase K00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148]
D TWT_186 ispG; 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase K03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3]
D TWT_642 ispH1; IspH protein 1 K03527 ispH; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4]
D TWT_217 idsA; geranylgeranyl pyrophosphate synthase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D TWT_331 undecaprenyl pyrophosphate synthetase K12503 E2.5.1.68; short-chain Z-isoprenyl diphosphate synthase [EC:2.5.1.68]
D TWT_286 uppS; undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
C 00907 Pinene, camphor and geraniol degradation
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
D TWT_340 tkt; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis [PATH:twh00523]
D TWT_032 rmlA; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D TWT_030 rmlB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D TWT_031 rmlC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D TWT_029 rmlD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
D TWT_052 menF; isochorismate synthase K02552 menF; menaquinone-specific isochorismate synthase [EC:5.4.4.2]
C 01055 Biosynthesis of vancomycin group antibiotics
D TWT_030 rmlB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
C 00332 Carbapenem biosynthesis
C 00261 Monobactam biosynthesis [PATH:twh00261]
D TWT_708 ask; aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D TWT_707 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis [PATH:twh00521]
D TWT_213 glkA; glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D TWT_032 rmlA; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D TWT_030 rmlB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D TWT_031 rmlC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D TWT_029 rmlD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
D TWT_213 glkA; glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
C 00525 Acarbose and validamycin biosynthesis [PATH:twh00525]
D TWT_032 rmlA; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D TWT_030 rmlB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
C 00401 Novobiocin biosynthesis
D TWT_050 tyrA; prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
D TWT_386 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
C 00333 Prodigiosin biosynthesis
D TWT_254 fabD; malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D TWT_313 fabG; 3-oxoacyl-[acyl-carrier protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
D TWT_252 acp; acyl carrier protein K02078 acpP; acyl carrier protein
C 00999 Biosynthesis of various plant secondary metabolites
D TWT_360 metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
C 00997 Biosynthesis of various other secondary metabolites
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation
C 00627 Aminobenzoate degradation
C 00364 Fluorobenzoate degradation
C 00625 Chloroalkane and chloroalkene degradation
C 00361 Chlorocyclohexane and chlorobenzene degradation
C 00623 Toluene degradation
C 00622 Xylene degradation
C 00633 Nitrotoluene degradation
C 00642 Ethylbenzene degradation
C 00643 Styrene degradation
C 00791 Atrazine degradation
C 00930 Caprolactam degradation
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
C 00626 Naphthalene degradation
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:twh03020]
D TWT_071 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D TWT_072 rpoC; DNA-directed RNA polymerase beta' chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D TWT_528 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D TWT_362 rpoZ; DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
C 03022 Basal transcription factors
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:twh03010]
D TWT_293 rpsA; 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D TWT_449 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D TWT_548 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D TWT_378 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D TWT_538 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D TWT_108 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D TWT_676 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D TWT_541 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D TWT_145 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D TWT_555 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D TWT_529 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D TWT_677 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D TWT_530 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D TWT_115 rpsN; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D TWT_422 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D TWT_461 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D TWT_545 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D TWT_106 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D TWT_550 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D TWT_276 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D TWT_713 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D TWT_551 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D TWT_554 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D TWT_553 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D TWT_542 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D TWT_540 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D TWT_711 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D TWT_105 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D TWT_712 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D TWT_714 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D TWT_144 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D TWT_544 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D TWT_536 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D TWT_547 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D TWT_527 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D TWT_539 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D TWT_457 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D TWT_166 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D TWT_473 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D TWT_549 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D TWT_552 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D TWT_543 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D TWT_654 rplY; 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25
D TWT_472 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D TWT_113 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D TWT_546 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D TWT_537 rpmD; 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30
D TWT_314 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D TWT_563 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D TWT_114 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D TWT_808 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D TWT_165 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D TWT_531 rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36
D TWT_RNA11 rrs; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D TWT_RNA12 rrl; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D TWT_RNA13 rrf; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
C 00970 Aminoacyl-tRNA biosynthesis [PATH:twh00970]
D TWT_RNA32 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D TWT_RNA34 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D TWT_RNA02 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D TWT_RNA50 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D TWT_RNA31 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D TWT_RNA25 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D TWT_RNA20 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D TWT_RNA19 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D TWT_RNA37 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D TWT_RNA09 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D TWT_RNA27 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D TWT_RNA16 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D TWT_RNA39 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D TWT_RNA10 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D TWT_RNA36 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D TWT_RNA35 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D TWT_RNA41 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D TWT_RNA26 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D TWT_RNA54 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D TWT_RNA30 tRNA-His K14226 tRNA-His; tRNA His
D TWT_RNA01 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D TWT_RNA53 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D TWT_RNA40 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D TWT_RNA22 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D TWT_RNA21 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D TWT_RNA52 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D TWT_RNA44 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D TWT_RNA15 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D TWT_RNA23 tRNA-Met K14230 tRNA-Met; tRNA Met
D TWT_RNA03 tRNA-Met K14230 tRNA-Met; tRNA Met
D TWT_RNA43 tRNA-Met K14230 tRNA-Met; tRNA Met
D TWT_RNA08 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D TWT_RNA38 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D TWT_RNA42 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D TWT_RNA46 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D TWT_RNA06 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D TWT_RNA33 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D TWT_RNA51 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D TWT_RNA49 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D TWT_RNA48 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D TWT_RNA07 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D TWT_RNA04 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D TWT_RNA24 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D TWT_RNA45 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D TWT_RNA47 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D TWT_RNA05 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D TWT_RNA28 tRNA-Val K14237 tRNA-Val; tRNA Val
D TWT_RNA29 tRNA-Val K14237 tRNA-Val; tRNA Val
D TWT_RNA17 tRNA-Val K14237 tRNA-Val; tRNA Val
D TWT_209 gltS; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D TWT_412 gatA; glutamyl-tRNA(Gln) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D TWT_411 gatB; glutamyl-tRNA(Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D TWT_413 gatC; glutamyl-tRNA(Gln) amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D TWT_376 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D TWT_500 glyQS; glycyl-tRNA synthetase alpha chain and beta chain K14164 glyQS; glycyl-tRNA synthetase [EC:6.1.1.14]
D TWT_262 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D TWT_726 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D TWT_316 cysS2; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D TWT_347 cysS1; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D TWT_763 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D TWT_358 fmt; methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D TWT_478 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D TWT_385 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D TWT_477 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D TWT_062 lysS; lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D TWT_351 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D TWT_183 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D TWT_785 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D TWT_167 pheS; phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D TWT_168 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D TWT_169 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D TWT_686 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:twh03060]
D TWT_535 secY; preprotein translocase SecY subunit K03076 secY; preprotein translocase subunit SecY
D TWT_716 unknown K03073 secE; preprotein translocase subunit SecE
D TWT_303 secG; preprotein translocase SecG subunit K03075 secG; preprotein translocase subunit SecG
D TWT_271 secD; preprotein translocase SecD subunit K03072 secD; preprotein translocase subunit SecD
D TWT_272 secF; protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF
D TWT_270 unknown K03210 yajC; preprotein translocase subunit YajC
D TWT_805 stage III sporulation protein J-like protein K03217 yidC; YidC/Oxa1 family membrane protein insertase
D TWT_130 secA; preprotein translocase SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D TWT_462 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D TWT_556 ftsY; cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor
D TWT_320 tatC; twin-arginine translocase TatC component K03118 tatC; sec-independent protein translocase protein TatC
D TWT_456 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D TWT_512 lpsA; lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36]
C 04141 Protein processing in endoplasmic reticulum
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system [PATH:twh04122]
D TWT_416 cysteine desulfurase NifS-like protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D TWT_390 sseA; thiosulfate sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D TWT_415 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
C 03050 Proteasome
C 03018 RNA degradation [PATH:twh03018]
D TWT_474 rng; ribonuclease G K08300 rne; ribonuclease E [EC:3.1.26.12]
D TWT_783 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D TWT_421 gpsI; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D TWT_436 rho; transcription termination factor Rho K03628 rho; transcription termination factor Rho
D TWT_615 unknown K12574 rnj; ribonuclease J [EC:3.1.-.-]
D TWT_750 dnaK; chaperone protein K04043 dnaK; molecular chaperone DnaK
D TWT_441 groEL2; 60 kDa chaperonin 2 K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D TWT_800 pcnA; poly(A) polymerase K00970 pcnB; poly(A) polymerase [EC:2.7.7.19]
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:twh03030]
D TWT_510 dnaE; DNA polymerase III alpha chain K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D TWT_710 dnaZX; DNA polymerase III gamma and tau subunit K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D TWT_694 putative DNA polymerase III delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D TWT_381 holA; DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D TWT_002 dnaN; DNA polymerase III beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D TWT_738 dnaC; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D TWT_288 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D TWT_107 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D TWT_403 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D TWT_239 rnhA; ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D TWT_414 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03410 Base excision repair [PATH:twh03410]
D TWT_582 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
D TWT_396 putative DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D TWT_744 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D TWT_685 putative exodeoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D TWT_444 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D TWT_414 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03420 Nucleotide excision repair [PATH:twh03420]
D TWT_182 trcF; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D TWT_296 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
D TWT_295 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
D TWT_297 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
D TWT_080 pcrA; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TWT_517 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TWT_519 putative DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TWT_414 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03430 Mismatch repair [PATH:twh03430]
D TWT_080 pcrA; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TWT_517 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TWT_519 putative DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TWT_643 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D TWT_644 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D TWT_107 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D TWT_403 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D TWT_510 dnaE; DNA polymerase III alpha chain K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D TWT_002 dnaN; DNA polymerase III beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D TWT_710 dnaZX; DNA polymerase III gamma and tau subunit K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D TWT_381 holA; DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D TWT_694 putative DNA polymerase III delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D TWT_414 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03440 Homologous recombination [PATH:twh03440]
D TWT_107 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D TWT_403 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D TWT_003 recF; recF protein K03629 recF; DNA replication and repair protein RecF
D TWT_285 recO; DNA repair protein K03584 recO; DNA repair protein RecO (recombination protein O)
D TWT_709 recR; recombination protein K06187 recR; recombination protein RecR
D TWT_611 recA; recombinase A K03553 recA; recombination protein RecA
D TWT_268 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D TWT_269 ruvB; holliday junction binding protein RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D TWT_267 ruvC; crossover junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D TWT_566 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D TWT_510 dnaE; DNA polymerase III alpha chain K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D TWT_002 dnaN; DNA polymerase III beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D TWT_710 dnaZX; DNA polymerase III gamma and tau subunit K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D TWT_381 holA; DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D TWT_694 putative DNA polymerase III delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D TWT_359 putative primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
C 03450 Non-homologous end-joining
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus
C 03265 Virion - Ebolavirus and Lyssavirus
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:twh02010]
D TWT_328 sugar ABC transporter substrate-binding protein (L-arabinose/D-xylose) K10546 chvE; putative multiple sugar transport system substrate-binding protein
D TWT_329 sugar ABC transporter permease protein (L-arabinose/D-xylose) K10547 gguB; putative multiple sugar transport system permease protein
D TWT_330 sugar ABC transporter ATP-binding protein (L-arabinose/D-xylose) K10548 gguA; putative multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D TWT_355 phoS; phosphate transport system substrate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D TWT_354 pstC; phosphate transport system permease protein K02037 pstC; phosphate transport system permease protein
D TWT_353 pstA; phosphate transport system permease protein K02038 pstA; phosphate transport system permease protein
D TWT_352 phoT; phosphate ABC transporter ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D TWT_561 branched-chain amino acid ABC transporter substrate-binding protein K01999 livK; branched-chain amino acid transport system substrate-binding protein
D TWT_560 branched-chain amino acid ABC transporter permease protein K01997 livH; branched-chain amino acid transport system permease protein
D TWT_559 branched-chain amino acid ABC transporter permease protein K01998 livM; branched-chain amino acid transport system permease protein
D TWT_558 branched-chain amino acid ABC transporter ATP-binding protein K01995 livG; branched-chain amino acid transport system ATP-binding protein
D TWT_557 branched-chain amino acid ABC transporter ATP-binding protein K01996 livF; branched-chain amino acid transport system ATP-binding protein
D TWT_136 dppA1; dipeptide ABC transporter substrate-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein
D TWT_056 fecB; iron (III) dicitrate ABC transporter substrate-binding protein K25286 fagD; iron-siderophore transport system substrate-binding protein
D TWT_662 iron ABC transporter substrate-binding protein K11601 mntC; manganese transport system substrate-binding protein
D TWT_664 iron ABC transporter permease protein K11602 mntB; manganese transport system permease protein
D TWT_663 iron ABC transporter ATP-binding protein K11603 mntA; manganese transport system ATP-binding protein [EC:7.2.2.5]
D TWT_211 bioY; biotin synthesis BioY protein K03523 bioY; biotin transport system substrate-specific component
D TWT_138 ABC transporter permease protein K16783 bioN; biotin transport system permease protein
D TWT_139 ABC transporter ATP-binding protein K16784 bioM; biotin transport system ATP-binding protein [EC:7.6.2.-]
D TWT_407 unknown K16785 ecfT; energy-coupling factor transport system permease protein
D TWT_200 ftsX; cell division protein FtsX K09811 ftsX; cell division transport system permease protein
D TWT_199 ftsE; cell division ATP-binding protein K09812 ftsE; cell division transport system ATP-binding protein
D TWT_601 ABC transporter ATP-binding protein K16012 cydC; ATP-binding cassette, subfamily C, bacterial CydC
D TWT_600 ABC transporter ATP-binding protein K16013 cydD; ATP-binding cassette, subfamily C, bacterial CydD
C 02060 Phosphotransferase system (PTS)
C 03070 Bacterial secretion system [PATH:twh03070]
D TWT_271 secD; preprotein translocase SecD subunit K03072 secD; preprotein translocase subunit SecD
D TWT_272 secF; protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF
D TWT_716 unknown K03073 secE; preprotein translocase subunit SecE
D TWT_303 secG; preprotein translocase SecG subunit K03075 secG; preprotein translocase subunit SecG
D TWT_535 secY; preprotein translocase SecY subunit K03076 secY; preprotein translocase subunit SecY
D TWT_270 unknown K03210 yajC; preprotein translocase subunit YajC
D TWT_805 stage III sporulation protein J-like protein K03217 yidC; YidC/Oxa1 family membrane protein insertase
D TWT_130 secA; preprotein translocase SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D TWT_556 ftsY; cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor
D TWT_462 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D TWT_320 tatC; twin-arginine translocase TatC component K03118 tatC; sec-independent protein translocase protein TatC
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:twh02020]
D TWT_355 phoS; phosphate transport system substrate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D TWT_338 ctaA; cytochrome AA3 controlling prrotein K02259 COX15; heme a synthase [EC:1.17.99.9]
D TWT_625 putative serine protease K08372 pepD; putative serine protease PepD [EC:3.4.21.-]
D TWT_001 dnaA; chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein
D TWT_662 iron ABC transporter substrate-binding protein K11601 mntC; manganese transport system substrate-binding protein
D TWT_663 iron ABC transporter ATP-binding protein K11603 mntA; manganese transport system ATP-binding protein [EC:7.2.2.5]
D TWT_664 iron ABC transporter permease protein K11602 mntB; manganese transport system permease protein
D TWT_410 unknown K18353 vanJ; vancomycin resistance protein VanJ
D TWT_701 putative type II/type IV pathway secretion protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D TWT_189 putative type II/type IV pathway secretion protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D TWT_700 unknown K12510 tadB; tight adherence protein B
D TWT_190 unknown K12510 tadB; tight adherence protein B
D TWT_191 unknown K12511 tadC; tight adherence protein C
D TWT_261 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:twh02024]
D TWT_386 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D TWT_215 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
D TWT_561 branched-chain amino acid ABC transporter substrate-binding protein K01999 livK; branched-chain amino acid transport system substrate-binding protein
D TWT_560 branched-chain amino acid ABC transporter permease protein K01997 livH; branched-chain amino acid transport system permease protein
D TWT_559 branched-chain amino acid ABC transporter permease protein K01998 livM; branched-chain amino acid transport system permease protein
D TWT_558 branched-chain amino acid ABC transporter ATP-binding protein K01995 livG; branched-chain amino acid transport system ATP-binding protein
D TWT_557 branched-chain amino acid ABC transporter ATP-binding protein K01996 livF; branched-chain amino acid transport system ATP-binding protein
D TWT_764 unknown K20276 bapA; large repetitive protein
D TWT_104 unknown K20276 bapA; large repetitive protein
D TWT_690 dipeptide ABC transporter substrate-binding-like protein K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]
D TWT_687 ribG; diaminohydroxyphosphoribosylaminopyrimidine deaminase K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
D TWT_136 dppA1; dipeptide ABC transporter substrate-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein
D TWT_137 dppA2; dipeptide ABC transporter substrate-binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D TWT_140 dppB; dipeptide transport system permease protein K02033 ABC.PE.P; peptide/nickel transport system permease protein
D TWT_141 dppC; dipeptide transport system permease protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D TWT_142 dppD; dipeptide transport system ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein
D TWT_805 stage III sporulation protein J-like protein K03217 yidC; YidC/Oxa1 family membrane protein insertase
D TWT_716 unknown K03073 secE; preprotein translocase subunit SecE
D TWT_303 secG; preprotein translocase SecG subunit K03075 secG; preprotein translocase subunit SecG
D TWT_535 secY; preprotein translocase SecY subunit K03076 secY; preprotein translocase subunit SecY
D TWT_270 unknown K03210 yajC; preprotein translocase subunit YajC
D TWT_130 secA; preprotein translocase SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D TWT_556 ftsY; cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor
D TWT_462 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis
C 02040 Flagellar assembly
D TWT_499 rpoD; RNA polymerase sigma factor K03086 rpoD; RNA polymerase primary sigma factor
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
D TWT_783 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04980 Cobalamin transport and metabolism
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance [PATH:twh01501]
D TWT_136 dppA1; dipeptide ABC transporter substrate-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein
D TWT_222 pbpB; penicillin-binding protein 2 K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
C 01502 Vancomycin resistance [PATH:twh01502]
D TWT_505 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D TWT_495 alanine racemase-like protein K01775 alr; alanine racemase [EC:5.1.1.1]
D TWT_496 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D TWT_223 murF; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D TWT_224 murX; phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D TWT_228 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D TWT_410 unknown K18353 vanJ; vancomycin resistance protein VanJ
C 01503 Cationic antimicrobial peptide (CAMP) resistance
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:twh01000]
C 01001 Protein kinases [BR:twh01001]
D TWT_216 pknB; serine/threonine-protein kinase K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D TWT_777 pknA; serine/threonine-protein kinase K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D TWT_778 probable serine/threonine protein kinase K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D TWT_046 two-component system sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D TWT_632 two-component system sensor histidine kinase K00936 pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3]
C 01009 Protein phosphatases and associated proteins [BR:twh01009]
D TWT_090 protein phosphatase K20074 prpC; PPM family protein phosphatase [EC:3.1.3.16]
C 01002 Peptidases and inhibitors [BR:twh01002]
D TWT_512 lpsA; lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36]
D TWT_079 guaA; GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D TWT_149 NPL/P60 family secreted protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
D TWT_289 NPL/P60 family secreted protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
D TWT_723 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D TWT_606 glmS; glucosamine--fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D TWT_564 unknown K07284 srtA; sortase A [EC:3.4.22.70]
D TWT_399 pepD; aminopeptidase K01256 pepN; aminopeptidase N [EC:3.4.11.2]
D TWT_769 metalloendopeptidase K07386 pepO; putative endopeptidase [EC:3.4.24.-]
D TWT_501 pepB; aminopeptidase A/I K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D TWT_259 map; methionine aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D TWT_522 pepQ; peptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
D TWT_588 ftsH; cell division protein FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D TWT_013 putative protease HtpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D TWT_625 putative serine protease K08372 pepD; putative serine protease PepD [EC:3.4.21.-]
D TWT_493 ptrB; protease II K01354 ptrB; oligopeptidase B [EC:3.4.21.83]
D TWT_327 dacB; serine-type D-Ala-D-Ala carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D TWT_480 clpP2; ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
D TWT_481 clpP1; ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
D TWT_628 predicted secreted protein K07177 K07177; Lon-like protease
D TWT_456 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
C 01003 Glycosyltransferases [BR:twh01003]
D TWT_765 glycosyltransferase K00721 DPM1; dolichol-phosphate mannosyltransferase [EC:2.4.1.83]
D TWT_121 unknown K00728 POMT; dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109]
D TWT_033 wbbL; glycosyl transferase K16870 wbbL; N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase [EC:2.4.1.289]
C 01005 Lipopolysaccharide biosynthesis proteins [BR:twh01005]
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:twh01011]
D TWT_508 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D TWT_718 murB; UDP-N-acetylmuramate dehydrogenase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D TWT_229 murC; UDP-N-acetylmuramate--alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D TWT_226 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D TWT_225 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D TWT_505 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D TWT_495 alanine racemase-like protein K01775 alr; alanine racemase [EC:5.1.1.1]
D TWT_496 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D TWT_224 murX; phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D TWT_228 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D TWT_315 undecaprenol kinase-like protein K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D TWT_799 transmembrane protein K03980 murJ; putative peptidoglycan lipid II flippase
D TWT_222 pbpB; penicillin-binding protein 2 K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D TWT_776 pbpA; penicillin-binding protein K05364 pbpA; penicillin-binding protein A
D TWT_327 dacB; serine-type D-Ala-D-Ala carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D TWT_149 NPL/P60 family secreted protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
D TWT_289 NPL/P60 family secreted protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
D TWT_564 unknown K07284 srtA; sortase A [EC:3.4.22.70]
D TWT_374 unknown K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]
C 01004 Lipid biosynthesis proteins [BR:twh01004]
D TWT_254 fabD; malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D TWT_253 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D TWT_251 kasA; 3-oxoacyl-[acyl-carrier-protein] synthase K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D TWT_313 fabG; 3-oxoacyl-[acyl-carrier protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D TWT_214 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
C 01008 Polyketide biosynthesis proteins
C 01006 Prenyltransferases [BR:twh01006]
D TWT_217 idsA; geranylgeranyl pyrophosphate synthase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D TWT_331 undecaprenyl pyrophosphate synthetase K12503 E2.5.1.68; short-chain Z-isoprenyl diphosphate synthase [EC:2.5.1.68]
D TWT_286 uppS; undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D TWT_609 miaA; tRNA isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D TWT_070 menA; 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]
D TWT_339 ctaB; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
C 01007 Amino acid related enzymes [BR:twh01007]
D TWT_062 lysS; lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D TWT_209 gltS; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D TWT_169 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D TWT_686 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D TWT_316 cysS2; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D TWT_347 cysS1; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D TWT_351 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D TWT_763 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D TWT_477 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D TWT_478 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D TWT_385 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D TWT_785 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D TWT_726 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D TWT_183 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D TWT_262 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D TWT_376 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D TWT_167 pheS; phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D TWT_168 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D TWT_633 gabT; 4-aminobutyrate aminotransferase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D TWT_729 hemL; glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D TWT_208 ilvE; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins [BR:twh00194]
D TWT_423 atpC; ATP synthase epsilon chain K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D TWT_424 atpD; ATP synthase beta chain K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D TWT_425 atpG; ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D TWT_426 atpA; ATP synthase alpha chain K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D TWT_427 atpH; ATP synthase delta chain K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D TWT_428 atpF; ATP synthase B chain K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D TWT_429 atpE; ATP synthase C chain K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D TWT_430 atpB; ATP synthase A chain K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D TWT_431 unknown K02116 atpI; ATP synthase protein I
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:twh03000]
D TWT_747 hspR; heat shock regulator K13640 hspR; MerR family transcriptional regulator, heat shock protein HspR
D TWT_112 iron-dependent repressor ideR K26252 dtxR; DtxR family transcriptional regulator, iron-dependent repressor
D TWT_024 birA; biotin acetyl-CoA carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D TWT_618 wblE; putative transcription regulatory protein K18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator
D TWT_123 whiB; putative sporulation regulatory protein K18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator
D TWT_801 parB; chromosome partitioning protein ParB K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D TWT_349 transcriptional regulator K07736 carD; CarD family transcriptional regulator, regulator of rRNA transcription
D TWT_237 transcriptional regulator K07738 nrdR; transcriptional repressor NrdR
D TWT_219 MraZ protein K03925 mraZ; transcriptional regulator MraZ
C 03021 Transcription machinery [BR:twh03021]
D TWT_528 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D TWT_071 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D TWT_072 rpoC; DNA-directed RNA polymerase beta' chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D TWT_362 rpoZ; DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D TWT_499 rpoD; RNA polymerase sigma factor K03086 rpoD; RNA polymerase primary sigma factor
D TWT_156 nusA; N utilization substance protein A K02600 nusA; transcription termination/antitermination protein NusA
D TWT_715 nusG; transcription antitermination protein K02601 nusG; transcription termination/antitermination protein NusG
D TWT_680 greA; transcription elongation factor K03624 greA; transcription elongation factor GreA
D TWT_436 rho; transcription termination factor Rho K03628 rho; transcription termination factor Rho
C 03019 Messenger RNA biogenesis [BR:twh03019]
D TWT_474 rng; ribonuclease G K08300 rne; ribonuclease E [EC:3.1.26.12]
D TWT_562 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D TWT_615 unknown K12574 rnj; ribonuclease J [EC:3.1.-.-]
D TWT_406 orn; oligoribonuclease K13288 orn; oligoribonuclease [EC:3.1.-.-]
D TWT_783 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D TWT_421 gpsI; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D TWT_436 rho; transcription termination factor Rho K03628 rho; transcription termination factor Rho
D TWT_750 dnaK; chaperone protein K04043 dnaK; molecular chaperone DnaK
D TWT_441 groEL2; 60 kDa chaperonin 2 K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D TWT_800 pcnA; poly(A) polymerase K00970 pcnB; poly(A) polymerase [EC:2.7.7.19]
C 03041 Spliceosome
C 03011 Ribosome [BR:twh03011]
D TWT_293 rpsA; 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D TWT_449 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D TWT_548 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D TWT_378 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D TWT_538 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D TWT_108 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D TWT_676 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D TWT_541 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D TWT_145 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D TWT_555 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D TWT_529 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D TWT_677 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D TWT_530 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D TWT_115 rpsN; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D TWT_422 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D TWT_461 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D TWT_545 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D TWT_106 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D TWT_550 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D TWT_276 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D TWT_713 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D TWT_551 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D TWT_554 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D TWT_553 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D TWT_542 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D TWT_540 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D TWT_105 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D TWT_712 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D TWT_714 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D TWT_711 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D TWT_144 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D TWT_544 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D TWT_536 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D TWT_547 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D TWT_527 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D TWT_539 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D TWT_457 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D TWT_166 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D TWT_473 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D TWT_549 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D TWT_552 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D TWT_543 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D TWT_472 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D TWT_113 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D TWT_546 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D TWT_537 rpmD; 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30
D TWT_314 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D TWT_563 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D TWT_114 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D TWT_808 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D TWT_165 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D TWT_531 rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36
D TWT_654 rplY; 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25
D TWT_RNA13 rrf; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D TWT_RNA11 rrs; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D TWT_RNA12 rrl; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
C 03009 Ribosome biogenesis [BR:twh03009]
D TWT_562 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D TWT_406 orn; oligoribonuclease K13288 orn; oligoribonuclease [EC:3.1.-.-]
D TWT_284 era; GTP-binding protein Era-like protein K03595 era; GTPase
D TWT_471 obg; GTP-binding protein K03979 obgE; GTPase [EC:3.6.5.-]
D TWT_156 nusA; N utilization substance protein A K02600 nusA; transcription termination/antitermination protein NusA
D TWT_715 nusG; transcription antitermination protein K02601 nusG; transcription termination/antitermination protein NusG
D TWT_203 ksgA; dimethyladenosine transferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D TWT_281 unknown K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]
D TWT_220 unknown K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]
D TWT_346 tRNA/rRNA methyltransferase K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]
D TWT_511 pseudouridylate synthase-like protein K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D TWT_459 rimM; 16S rRNA processing protein K02860 rimM; 16S rRNA processing protein RimM
D TWT_474 rng; ribonuclease G K08300 rne; ribonuclease E [EC:3.1.26.12]
D TWT_375 unknown K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]
D TWT_051 cytidylate kinase/GTP-binding protein fusion K03977 engA; GTPase
D TWT_433 unknown K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D TWT_275 relA; GTP pyrophosphokinase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
D TWT_159 rbfA; ribosome-binding factor A K02834 rbfA; ribosome-binding factor A
D TWT_283 unknown K07042 ybeY; probable rRNA maturation factor
D TWT_639 GTP-binding protein K06942 ychF; ribosome-binding ATPase
C 03016 Transfer RNA biogenesis [BR:twh03016]
D TWT_209 gltS; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D TWT_183 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D TWT_477 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D TWT_385 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D TWT_763 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D TWT_351 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D TWT_376 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D TWT_262 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D TWT_726 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D TWT_316 cysS2; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D TWT_347 cysS1; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D TWT_478 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D TWT_785 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D TWT_167 pheS; phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D TWT_168 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D TWT_169 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D TWT_686 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D TWT_282 HIT-like protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D TWT_318 protein-L-isoaspartate methyltransferase K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D TWT_526 truA; pseudouridylate synthase I K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D TWT_087 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D TWT_416 cysteine desulfurase NifS-like protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D TWT_433 unknown K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D TWT_609 miaA; tRNA isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D TWT_807 unknown K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D TWT_RNA18 rnpB; RNA subunit (M1 RNA) of ribonuclease P K01978 rnpB; M1 RNA
D TWT_622 rph; ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D TWT_394 rnd; ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
D TWT_062 lysS; lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D TWT_500 glyQS; glycyl-tRNA synthetase alpha chain and beta chain K14164 glyQS; glycyl-tRNA synthetase [EC:6.1.1.14]
D TWT_751 unknown K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
D TWT_610 unknown K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
D TWT_458 trmD; tRNA (guanine-N1-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D TWT_415 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D TWT_656 unknown K06980 ygfZ; tRNA-modifying protein YgfZ
D TWT_152 tgt; queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D TWT_590 cell cycle protein MesJ-like protein K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D TWT_593 holo-[acyl-carrier protein] synthase K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D TWT_421 gpsI; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
C 03012 Translation factors [BR:twh03012]
D TWT_157 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D TWT_164 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D TWT_448 tsf; elongation factor EF-Ts K02357 tsf; elongation factor Ts
D TWT_120 tuf; elongation factor EF-Tu K02358 tuf; elongation factor Tu
D TWT_675 fusA; elongation factor EF-G K02355 fusA; elongation factor G
D TWT_435 prfA; peptide chain release factor RF-1 K02835 prfA; peptide chain release factor 1
D TWT_446 frr; ribosome recycling factor K02838 frr; ribosome recycling factor
D TWT_434 hemK; protoporphyrinogen oxidase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D TWT_651 pth; peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]
D TWT_532 infA; translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1
D TWT_368 efp; elongation factor EF-P K02356 efp; elongation factor P
D TWT_198 prfB; peptide chain release factor RF-2 K02836 prfB; peptide chain release factor 2
C 03110 Chaperones and folding catalysts [BR:twh03110]
D TWT_746 clpB; ATP-dependent protase ATP-binding subunit K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
D TWT_065 clpC; ATP-dependent Clp protease ATP-binding subunit K03696 clpC; ATP-dependent Clp protease ATP-binding subunit ClpC
D TWT_479 clpX; ATP-dependent Clp protease ATP-binding subunit K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
D TWT_750 dnaK; chaperone protein K04043 dnaK; molecular chaperone DnaK
D TWT_441 groEL2; 60 kDa chaperonin 2 K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D TWT_280 dnaJ2; chaperone protein K03686 dnaJ; molecular chaperone DnaJ
D TWT_748 cbpA; curved DNA-binding protein K05516 cbpA; curved DNA-binding protein
D TWT_749 grpE; HSP-70 cofactor GrpE K03687 GRPE; molecular chaperone GrpE
D TWT_074 groES; 10 kDa chaperone K04078 groES; chaperonin GroES
D TWT_588 ftsH; cell division protein FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D TWT_430 atpB; ATP synthase A chain K02108 ATPF0A; F-type H+-transporting ATPase subunit a
C 04131 Membrane trafficking [BR:twh04131]
D TWT_475 ndkA; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D TWT_300 gap; glyceraldehyde 3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D TWT_655 gpm; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D TWT_290 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
C 04121 Ubiquitin system
C 03051 Proteasome
C 03032 DNA replication proteins [BR:twh03032]
D TWT_239 rnhA; ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D TWT_116 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D TWT_001 dnaA; chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein
D TWT_738 dnaC; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D TWT_288 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D TWT_107 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D TWT_403 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D TWT_510 dnaE; DNA polymerase III alpha chain K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D TWT_002 dnaN; DNA polymerase III beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D TWT_381 holA; DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D TWT_694 putative DNA polymerase III delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D TWT_710 dnaZX; DNA polymerase III gamma and tau subunit K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D TWT_414 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TWT_491 gyrA2; DNA gyrase subunit A-like protein K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D TWT_006 gyrA1; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D TWT_494 gyrB2; DNA gyrase subunit B-like protein K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D TWT_005 gyrB1; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D TWT_696 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C 03036 Chromosome and associated proteins [BR:twh03036]
D TWT_562 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D TWT_116 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D TWT_748 cbpA; curved DNA-binding protein K05516 cbpA; curved DNA-binding protein
D TWT_001 dnaA; chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein
D TWT_395 dps; stress induced DNA-binding protein K04047 dps; starvation-inducible DNA-binding protein
D TWT_199 ftsE; cell division ATP-binding protein K09812 ftsE; cell division transport system ATP-binding protein
D TWT_222 pbpB; penicillin-binding protein 2 K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D TWT_614 ftsK; cell division protein FtsK K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family
D TWT_230 ftsQ; cell division protein FtsQ K03589 ftsQ; cell division protein FtsQ
D TWT_227 ftsW; cell division protein FtsW K03588 ftsW; cell division protein FtsW
D TWT_200 ftsX; cell division protein FtsX K09811 ftsX; cell division transport system permease protein
D TWT_515 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D TWT_513 cell division protein DivIVA-like protein K04074 divIVA; cell division initiation protein
D TWT_514 unknown K09772 sepF; cell division inhibitor SepF
D TWT_802 parA1; chromosome partitioning protein ParA K03496 parA; chromosome partitioning protein
D TWT_049 soj; putative sporulation protein Soj K03496 parA; chromosome partitioning protein
D TWT_631 parA2; putative plasmid partitioning protein K03496 parA; chromosome partitioning protein
D TWT_801 parB; chromosome partitioning protein ParB K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D TWT_452 xerC; integrase/recombinase K03733 xerC; integrase/recombinase XerC
D TWT_097 xerD; integrase/recombinase K04763 xerD; integrase/recombinase XerD
D TWT_525 mrp; ATP-binding Mrp protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
D TWT_298 whiA; putative sporulation regulatory protein K09762 whiA; cell division protein WhiA
C 03400 DNA repair and recombination proteins [BR:twh03400]
D TWT_465 ogt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D TWT_582 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
D TWT_660 unknown K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D TWT_487 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D TWT_396 putative DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D TWT_744 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D TWT_685 putative exodeoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D TWT_444 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D TWT_414 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TWT_296 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
D TWT_295 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
D TWT_297 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
D TWT_080 pcrA; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TWT_517 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TWT_519 putative DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TWT_071 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D TWT_072 rpoC; DNA-directed RNA polymerase beta' chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D TWT_528 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D TWT_362 rpoZ; DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D TWT_182 trcF; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D TWT_643 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D TWT_644 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D TWT_510 dnaE; DNA polymerase III alpha chain K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D TWT_002 dnaN; DNA polymerase III beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D TWT_381 holA; DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D TWT_694 putative DNA polymerase III delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D TWT_710 dnaZX; DNA polymerase III gamma and tau subunit K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D TWT_107 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D TWT_403 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D TWT_611 recA; recombinase A K03553 recA; recombination protein RecA
D TWT_268 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D TWT_269 ruvB; holliday junction binding protein RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D TWT_267 ruvC; crossover junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D TWT_359 putative primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D TWT_003 recF; recF protein K03629 recF; DNA replication and repair protein RecF
D TWT_566 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D TWT_285 recO; DNA repair protein K03584 recO; DNA repair protein RecO (recombination protein O)
D TWT_709 recR; recombination protein K06187 recR; recombination protein RecR
D TWT_102 recN; recombination and DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D TWT_491 gyrA2; DNA gyrase subunit A-like protein K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D TWT_006 gyrA1; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D TWT_494 gyrB2; DNA gyrase subunit B-like protein K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D TWT_005 gyrB1; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D TWT_696 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D TWT_116 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D TWT_098 unknown K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D TWT_683 nrdA; ribonucleotide reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D TWT_682 nrdB; ribonucleotide reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C 03029 Mitochondrial biogenesis [BR:twh03029]
D TWT_157 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D TWT_164 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D TWT_448 tsf; elongation factor EF-Ts K02357 tsf; elongation factor Ts
D TWT_120 tuf; elongation factor EF-Tu K02358 tuf; elongation factor Tu
D TWT_675 fusA; elongation factor EF-G K02355 fusA; elongation factor G
D TWT_284 era; GTP-binding protein Era-like protein K03595 era; GTPase
D TWT_169 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D TWT_385 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D TWT_351 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D TWT_412 gatA; glutamyl-tRNA(Gln) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D TWT_411 gatB; glutamyl-tRNA(Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D TWT_413 gatC; glutamyl-tRNA(Gln) amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D TWT_107 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D TWT_403 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D TWT_750 dnaK; chaperone protein K04043 dnaK; molecular chaperone DnaK
D TWT_749 grpE; HSP-70 cofactor GrpE K03687 GRPE; molecular chaperone GrpE
D TWT_441 groEL2; 60 kDa chaperonin 2 K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D TWT_074 groES; 10 kDa chaperone K04078 groES; chaperonin GroES
D TWT_280 dnaJ2; chaperone protein K03686 dnaJ; molecular chaperone DnaJ
D TWT_416 cysteine desulfurase NifS-like protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D TWT_525 mrp; ATP-binding Mrp protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
D TWT_339 ctaB; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D TWT_338 ctaA; cytochrome AA3 controlling prrotein K02259 COX15; heme a synthase [EC:1.17.99.9]
D TWT_805 stage III sporulation protein J-like protein K03217 yidC; YidC/Oxa1 family membrane protein insertase
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:twh02000]
D TWT_601 ABC transporter ATP-binding protein K16012 cydC; ATP-binding cassette, subfamily C, bacterial CydC
D TWT_600 ABC transporter ATP-binding protein K16013 cydD; ATP-binding cassette, subfamily C, bacterial CydD
D TWT_328 sugar ABC transporter substrate-binding protein (L-arabinose/D-xylose) K10546 chvE; putative multiple sugar transport system substrate-binding protein
D TWT_329 sugar ABC transporter permease protein (L-arabinose/D-xylose) K10547 gguB; putative multiple sugar transport system permease protein
D TWT_330 sugar ABC transporter ATP-binding protein (L-arabinose/D-xylose) K10548 gguA; putative multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D TWT_355 phoS; phosphate transport system substrate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D TWT_354 pstC; phosphate transport system permease protein K02037 pstC; phosphate transport system permease protein
D TWT_353 pstA; phosphate transport system permease protein K02038 pstA; phosphate transport system permease protein
D TWT_352 phoT; phosphate ABC transporter ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D TWT_561 branched-chain amino acid ABC transporter substrate-binding protein K01999 livK; branched-chain amino acid transport system substrate-binding protein
D TWT_560 branched-chain amino acid ABC transporter permease protein K01997 livH; branched-chain amino acid transport system permease protein
D TWT_559 branched-chain amino acid ABC transporter permease protein K01998 livM; branched-chain amino acid transport system permease protein
D TWT_558 branched-chain amino acid ABC transporter ATP-binding protein K01995 livG; branched-chain amino acid transport system ATP-binding protein
D TWT_557 branched-chain amino acid ABC transporter ATP-binding protein K01996 livF; branched-chain amino acid transport system ATP-binding protein
D TWT_136 dppA1; dipeptide ABC transporter substrate-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein
D TWT_137 dppA2; dipeptide ABC transporter substrate-binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D TWT_140 dppB; dipeptide transport system permease protein K02033 ABC.PE.P; peptide/nickel transport system permease protein
D TWT_141 dppC; dipeptide transport system permease protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D TWT_142 dppD; dipeptide transport system ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein
D TWT_056 fecB; iron (III) dicitrate ABC transporter substrate-binding protein K25286 fagD; iron-siderophore transport system substrate-binding protein
D TWT_057 iron ABC transporter substrate-binding protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D TWT_059 fepG; iron ABC transporter permease protein K02015 ABC.FEV.P; iron complex transport system permease protein
D TWT_060 fepD; iron ABC transporter permease protein K02015 ABC.FEV.P; iron complex transport system permease protein
D TWT_058 fepC; iron ABC transporter ATP-binding protein K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-]
D TWT_662 iron ABC transporter substrate-binding protein K11601 mntC; manganese transport system substrate-binding protein
D TWT_664 iron ABC transporter permease protein K11602 mntB; manganese transport system permease protein
D TWT_663 iron ABC transporter ATP-binding protein K11603 mntA; manganese transport system ATP-binding protein [EC:7.2.2.5]
D TWT_211 bioY; biotin synthesis BioY protein K03523 bioY; biotin transport system substrate-specific component
D TWT_138 ABC transporter permease protein K16783 bioN; biotin transport system permease protein
D TWT_139 ABC transporter ATP-binding protein K16784 bioM; biotin transport system ATP-binding protein [EC:7.6.2.-]
D TWT_407 unknown K16785 ecfT; energy-coupling factor transport system permease protein
D TWT_408 ABC transporter ATP-binding protein K01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D TWT_409 unknown K16925 ykoE; energy-coupling factor transport system permease protein
D TWT_200 ftsX; cell division protein FtsX K09811 ftsX; cell division transport system permease protein
D TWT_199 ftsE; cell division ATP-binding protein K09812 ftsE; cell division transport system ATP-binding protein
D TWT_178 unknown K01992 ABC-2.P; ABC-2 type transport system permease protein
D TWT_583 unknown K01992 ABC-2.P; ABC-2 type transport system permease protein
D TWT_035 ABC transporter permease protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D TWT_177 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D TWT_584 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D TWT_094 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D TWT_034 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D TWT_173 unknown K02004 ABC.CD.P; putative ABC transport system permease protein
D TWT_175 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D TWT_334 ABC transporter ATP-binding protein K09013 sufC; Fe-S cluster assembly ATP-binding protein
D TWT_180 unknown K26939 norM; MATE family, multidrug efflux pump
D TWT_645 MFS family transporter (D-galactonate) K08194 dgoT; MFS transporter, ACS family, D-galactonate transporter
D TWT_661 mscL; large-conductance mechanosensitive channel K03282 mscL; large conductance mechanosensitive channel
D TWT_202 unknown K21449 ata; trimeric autotransporter adhesin
D TWT_420 cation efflux protein K16264 czcD; cobalt-zinc-cadmium efflux system protein
D TWT_786 nhaA; sodium-proton antiporter K03313 nhaA; Na+:H+ antiporter, NhaA family
D TWT_799 transmembrane protein K03980 murJ; putative peptidoglycan lipid II flippase
D TWT_045 unknown K23675 fmnP; riboflavin transporter
D TWT_155 unknown K09125 yhhQ; queuosine precursor transporter
D TWT_603 unknown K22736 VIT; vacuolar iron transporter family protein
D TWT_227 ftsW; cell division protein FtsW K03588 ftsW; cell division protein FtsW
D TWT_757 ccsA; cytochrome c-type biogenesis protein K06196 ccdA; cytochrome c-type biogenesis protein
D TWT_740 unknown K07156 copC; copper resistance protein C
C 02044 Secretion system [BR:twh02044]
D TWT_701 putative type II/type IV pathway secretion protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D TWT_189 putative type II/type IV pathway secretion protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D TWT_700 unknown K12510 tadB; tight adherence protein B
D TWT_190 unknown K12510 tadB; tight adherence protein B
D TWT_191 unknown K12511 tadC; tight adherence protein C
D TWT_384 comEA; comE operon protein 1-like protein K02237 comEA; competence protein ComEA
D TWT_382 comE operon protein 3-like protein K02238 comEC; competence protein ComEC
D TWT_383 comE operon protein 3-like protein K02238 comEC; competence protein ComEC
D TWT_130 secA; preprotein translocase SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D TWT_271 secD; preprotein translocase SecD subunit K03072 secD; preprotein translocase subunit SecD
D TWT_716 unknown K03073 secE; preprotein translocase subunit SecE
D TWT_272 secF; protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF
D TWT_303 secG; preprotein translocase SecG subunit K03075 secG; preprotein translocase subunit SecG
D TWT_535 secY; preprotein translocase SecY subunit K03076 secY; preprotein translocase subunit SecY
D TWT_462 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D TWT_556 ftsY; cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor
D TWT_270 unknown K03210 yajC; preprotein translocase subunit YajC
D TWT_805 stage III sporulation protein J-like protein K03217 yidC; YidC/Oxa1 family membrane protein insertase
D TWT_320 tatC; twin-arginine translocase TatC component K03118 tatC; sec-independent protein translocase protein TatC
C 02042 Bacterial toxins
C 02022 Two-component system [BR:twh02022]
D TWT_046 two-component system sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D TWT_047 two-component system response regulator K02483 K02483; two-component system, OmpR family, response regulator
D TWT_632 two-component system sensor histidine kinase K00936 pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3]
D TWT_291 two-component system response regulator K22010 pdtaR; two-component system, response regulator PdtaR
C 02035 Bacterial motility proteins [BR:twh02035]
D TWT_701 putative type II/type IV pathway secretion protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D TWT_189 putative type II/type IV pathway secretion protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:twh04812]
D TWT_515 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D TWT_802 parA1; chromosome partitioning protein ParA K03496 parA; chromosome partitioning protein
D TWT_049 soj; putative sporulation protein Soj K03496 parA; chromosome partitioning protein
D TWT_631 parA2; putative plasmid partitioning protein K03496 parA; chromosome partitioning protein
D TWT_801 parB; chromosome partitioning protein ParB K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
C 04147 Exosome [BR:twh04147]
D TWT_783 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D TWT_300 gap; glyceraldehyde 3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D TWT_301 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D TWT_290 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D TWT_441 groEL2; 60 kDa chaperonin 2 K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D TWT_750 dnaK; chaperone protein K04043 dnaK; molecular chaperone DnaK
D TWT_342 gpi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D TWT_075 guaB1; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D TWT_076 guaB2; inosine-5'-monophosphate dehydrogenase-like protein K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D TWT_120 tuf; elongation factor EF-Tu K02358 tuf; elongation factor Tu
D TWT_282 HIT-like protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D TWT_534 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D TWT_261 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D TWT_730 hemB; porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D TWT_084 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D TWT_502 lpd; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D TWT_343 zwf; glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
D TWT_302 tpi; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D TWT_655 gpm; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
C 02048 Prokaryotic defense system [BR:twh02048]
D TWT_771 DNA modification methyltransferase K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72]
D TWT_515 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D TWT_209 gltS; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D TWT_416 cysteine desulfurase NifS-like protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules [BR:twh04090]
C 01504 Antimicrobial resistance genes [BR:twh01504]
D TWT_518 macrolide 2'-phosphotransferase-like protein K06979 mph; macrolide phosphotransferase
D TWT_410 unknown K18353 vanJ; vancomycin resistance protein VanJ
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:twh03100]
D TWT_RNA32 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D TWT_RNA34 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D TWT_RNA02 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D TWT_RNA50 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D TWT_RNA31 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D TWT_RNA25 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D TWT_RNA20 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D TWT_RNA19 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D TWT_RNA37 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D TWT_RNA09 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D TWT_RNA27 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D TWT_RNA16 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D TWT_RNA39 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D TWT_RNA10 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D TWT_RNA36 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D TWT_RNA35 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D TWT_RNA41 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D TWT_RNA26 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D TWT_RNA54 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D TWT_RNA30 tRNA-His K14226 tRNA-His; tRNA His
D TWT_RNA01 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D TWT_RNA53 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D TWT_RNA40 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D TWT_RNA22 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D TWT_RNA21 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D TWT_RNA52 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D TWT_RNA44 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D TWT_RNA15 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D TWT_RNA23 tRNA-Met K14230 tRNA-Met; tRNA Met
D TWT_RNA03 tRNA-Met K14230 tRNA-Met; tRNA Met
D TWT_RNA43 tRNA-Met K14230 tRNA-Met; tRNA Met
D TWT_RNA08 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D TWT_RNA38 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D TWT_RNA42 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D TWT_RNA46 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D TWT_RNA06 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D TWT_RNA33 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D TWT_RNA51 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D TWT_RNA49 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D TWT_RNA48 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D TWT_RNA07 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D TWT_RNA04 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D TWT_RNA24 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D TWT_RNA45 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D TWT_RNA47 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D TWT_RNA05 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D TWT_RNA28 tRNA-Val K14237 tRNA-Val; tRNA Val
D TWT_RNA29 tRNA-Val K14237 tRNA-Val; tRNA Val
D TWT_RNA17 tRNA-Val K14237 tRNA-Val; tRNA Val
D TWT_RNA11 rrs; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D TWT_RNA12 rrl; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D TWT_RNA13 rrf; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D TWT_RNA18 rnpB; RNA subunit (M1 RNA) of ribonuclease P K01978 rnpB; M1 RNA
D TWT_RNA14 ssrA; ssrA K15035 ssrA; transfer-messenger RNA
#
A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D TWT_016 2,5-diketo-D-gluconic acid reductase K06221 dkgA; 2,5-diketo-D-gluconate reductase A [EC:1.1.1.346]
D TWT_019 pyridine nucleotide-disulphide oxidoreductase class I K23842 lpdA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
D TWT_629 pyridine nucleotide-disulphide oxidoreductase class I K17883 mtr; mycothione reductase [EC:1.8.1.15]
D TWT_055 ferredoxin--NADP+ reductase K00528 fpr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1]
D TWT_659 acetyltransferase K15520 mshD; mycothiol synthase [EC:2.3.1.189]
D TWT_797 unknown K15521 mshA; D-inositol-3-phosphate glycosyltransferase [EC:2.4.1.250]
D TWT_650 php; phosphotriesterase-like protein K23149 E3.1.1.104; 5-phospho-D-xylono-1,4-lactonase [EC:3.1.1.104]
D TWT_400 unknown K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D TWT_325 deoxyribonuclease K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D TWT_310 def; formylmethionine deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88]
D TWT_798 unknown K15525 mshB; N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase [EC:3.5.1.103]
D TWT_319 putative FKBP-type peptidyl-prolyl cis-trans isomerase K01802 E5.2.1.8; peptidylprolyl isomerase [EC:5.2.1.8]
C 99981 Carbohydrate metabolism
C 99982 Energy metabolism
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
C 99986 Glycan metabolism
C 99987 Cofactor metabolism
C 99988 Secondary metabolism
C 99999 Others
D TWT_073 lysophospholipase/serine esterase fusion protein K06999 K06999; phospholipase/carboxylesterase
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D TWT_048 capB; cold shock protein B K03704 cspA; cold shock protein
C 99974 Translation
C 99975 Protein processing
D TWT_483 tig; trigger factor K03545 tig; trigger factor
D TWT_201 ssrB; tmRNA (SsrA)-binding protein K03664 smpB; SsrA-binding protein
D TWT_454 comM; competence protein ComM K07391 comM; magnesium chelatase family protein
D TWT_758 unknown K07399 resB; cytochrome c biogenesis protein
C 99976 Replication and repair
D TWT_640 rmuC; DNA recombination protein RmuC-like protein K09760 rmuC; DNA recombination protein RmuC
D TWT_091 unknown K07459 ybjD; putative ATP-dependent endonuclease of the OLD family
D TWT_455 unknown K07460 yraN; putative endonuclease
D TWT_453 smf; nucleotide-binding protein K04096 smf; DNA processing protein
C 99979 Viral proteins
C 99998 Others
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
C 99978 Cell growth
D TWT_804 R2H domain-containing protein K06346 jag; spoIIIJ-associated protein
C 99993 Cell motility
C 99995 Signaling proteins
D TWT_595 typA; GTP-binding protein TypA/BipA-like protein K06207 typA; GTP-binding protein
C 99992 Structural proteins
C 99994 Others
D TWT_509 tellurium resistence protein TerC-like protein K05794 terC; tellurite resistance protein TerC
B
B 09194 Poorly characterized
C 99996 General function prediction only
D TWT_337 iron regulated ABC transporter membrane component K09014 sufB; Fe-S cluster assembly protein SufB
D TWT_336 iron regulated ABC transporter membrane component K09015 sufD; Fe-S cluster assembly protein SufD
D TWT_391 unknown K02426 sufE; cysteine desulfuration protein SufE
D TWT_012 unknown K03744 lemA; LemA protein
D TWT_620 unknown K03975 dedA; membrane-associated protein
C 99997 Function unknown
D TWT_460 unknown K06960 K06960; uncharacterized protein
D TWT_706 unknown K07098 K07098; uncharacterized protein
D TWT_258 unknown K07164 K07164; uncharacterized protein
D TWT_806 unknown K08998 K08998; uncharacterized protein
D TWT_781 unknown K09009 K09009; uncharacterized protein
D TWT_626 unknown K09118 K09118; uncharacterized protein
D TWT_627 unknown K09118 K09118; uncharacterized protein
!
#
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: May 14, 2024