+F Repair protein KO
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DNA Repair and Recombination Proteins - Vibrio natriegens
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D PN96_16420 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D PN96_15235 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E PN96_11030 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E PN96_00780 adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E PN96_03240 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D PN96_11165 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PN96_17270 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PN96_19675 NTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D PN96_16420 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D PN96_15235 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D PN96_16970 deoxyribodipyrimidine photolyase K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
C BER (base exicision repair)
D DNA glycosylases
E PN96_11030 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E PN96_16415 3-methyladenine DNA glycosylase K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E PN96_00780 adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E PN96_07610 DNA-3-methyladenine glycosidase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E PN96_12425 formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E PN96_03240 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E PN96_08420 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E PN96_11035 endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E PN96_10975 ssDNA exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E PN96_09495 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E PN96_12825 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E PN96_00285 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E PN96_03280 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E PN96_03985 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E PN96_13730 uvrD; DNA-dependent helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E PN96_12825 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E PN96_09495 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F PN96_00120 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F PN96_00125 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F PN96_11875 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F PN96_12565 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F PN96_08545 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E PN96_01120 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E PN96_14540 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
E PN96_10940 DNA mismatch repair protein MutH K03573 mutH; DNA mismatch repair protein MutH
D DNA exonucleases
E PN96_07090 exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E PN96_10435 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E PN96_10070 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E PN96_02335 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E PN96_13315 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E PN96_00610 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E PN96_09905 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E PN96_03535 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E PN96_04180 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E PN96_23095 DNA polymerase III subunit alpha K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E PN96_14215 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E PN96_02390 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E PN96_02965 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E PN96_01710 DNA polymerase III subunit psi K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]
D DNA ligase
E PN96_09495 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E PN96_13730 uvrD; DNA-dependent helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E PN96_00300 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E PN96_14870 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E PN96_02010 exodeoxyribonuclease V subunit beta K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E PN96_02005 recC; exonuclease V subunit gamma K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E PN96_02015 exodeoxyribonuclease V subunit alpha K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E PN96_01130 recA; recombinase A K03553 recA; recombination protein RecA
E PN96_08180 ruvA; ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E PN96_08175 ruvB; ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E PN96_08185 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E PN96_12015 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E PN96_14885 primosomal replication protein N K02686 priB; primosomal replication protein N
E PN96_08390 prepilin peptidase K04067 priC; primosomal replication protein N''
E PN96_07090 exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E PN96_20120 exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E PN96_20115 exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E PN96_01130 recA; recombinase A K03553 recA; recombination protein RecA
E PN96_01775 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E PN96_13310 recF; recombination protein F K03629 recF; DNA replication and repair protein RecF
E PN96_12580 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E PN96_10975 ssDNA exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E PN96_01035 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E PN96_02975 recR; recombination protein RecR K06187 recR; recombination protein RecR
E PN96_10260 recombination and repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E PN96_10660 recombination associated protein K03554 rdgC; recombination associated protein RdgC
E PN96_08180 ruvA; ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E PN96_08175 ruvB; ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E PN96_08185 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E PN96_07500 carboxylate--amine ligase K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E PN96_20120 exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E PN96_20115 exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F PN96_04080 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F PN96_13305 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F PN96_08310 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F PN96_00165 DNA-binding protein K05787 hupA; DNA-binding protein HU-alpha
F PN96_08955 transcriptional regulator HU subunit alpha K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F PN96_10975 ssDNA exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F PN96_01035 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F PN96_02975 recR; recombination protein RecR K06187 recR; recombination protein RecR
F PN96_09495 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F PN96_14180 Fis family transcriptional regulator K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F PN96_07125 ihfA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F PN96_03630 ihfB; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F PN96_07090 exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F PN96_13755 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F PN96_02165 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F PN96_00285 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F PN96_03280 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F PN96_07820 transcriptional regulator K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D PN96_02160 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D PN96_01130 recA; recombinase A K03553 recA; recombination protein RecA
D PN96_14045 LexA family transcriptional regulator K01356 lexA; repressor LexA [EC:3.4.21.88]
D PN96_10260 recombination and repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D PN96_03975 DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D PN96_03605 recombinase RecA K14160 imuA; protein ImuA
D PN96_03600 nucleotidyltransferase K14161 imuB; protein ImuB
D PN96_03595 DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D PN96_00300 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D PN96_01135 recombinase RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D PN96_13145 ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D PN96_19730 DNA helicase IV K03658 helD; DNA helicase IV [EC:5.6.2.4]
D PN96_08380 ATP-dependent DNA helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D PN96_09195 ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D PN96_11165 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PN96_17270 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PN96_19675 NTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PN96_04070 ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D PN96_04065 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024