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Mitochondrial Biogenesis - Xenopus tropicalis (tropical clawed frog)
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AMitochondrial DNA transcription, translation, and replication factors
B Mitochondrial DNA-encoded proteins
C Mitochondrial respiratory chain complex I
D 3283492 ND1; NADH dehydrogenase subunit 1 K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
D 3283493 ND2; NADH dehydrogenase subunit 2 K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
D 3283499 ND3; NADH dehydrogenase subunit 3 K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
D 3283501 ND4; NADH dehydrogenase subunit 4 K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
D 3283500 ND4L; NADH dehydrogenase subunit 4L K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
D 3283502 ND5; NADH dehydrogenase subunit 5 K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
D 3283503 ND6; NADH dehydrogenase subunit 6 K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
C Mitochondrial respiratory chain complex III
D 3283504 CYTB; cytochrome b K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
C Cytochrome c oxidase
D 3283494 COX1; cytochrome c oxidase subunit I K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
D 3283495 COX2; cytochrome c oxidase subunit II K02261 COX2; cytochrome c oxidase subunit 2
D 3283498 COX3; cytochrome c oxidase subunit III K02262 COX3; cytochrome c oxidase subunit 3
C F-type ATPase
D 3283496 ATP8; ATP synthase F0 subunit 8 K02125 ATPeF08; F-type H+-transporting ATPase subunit 8
D 3283497 ATP6; ATP synthase F0 subunit 6 K02126 ATPeF0A; F-type H+-transporting ATPase subunit a
B Mitochondrial transcription and translation factors
C Mitochondrial RNA polymerase
D 100488061 polrmt; DNA-directed RNA polymerase, mitochondrial isoform X1 K10908 POLRMT; DNA-directed RNA polymerase, mitochondrial [EC:2.7.7.6]
C Mitochondrial transcription factors
D 100135718 tfam; transcription factor A, mitochondrial K11830 TFAM; transcription factor A, mitochondrial
D 549248 tfb1m; dimethyladenosine transferase 1, mitochondrial K15266 TFB1M; dimethyladenosine transferase 1, mitochondrial [EC:2.1.1.-]
D 100036660 tfb2m; dimethyladenosine transferase 2, mitochondrial K17653 TFB2M; dimethyladenosine transferase 2, mitochondrial [EC:2.1.1.-]
C Mitochondrial translation factors
D 100496951 mtif2; translation initiation factor IF-2, mitochondrial isoform X2 K02519 infB; translation initiation factor IF-2
D 780770 mtif3; translation initiation factor IF-3, mitochondrial K02520 infC; translation initiation factor IF-3
D 100497317 tsfm; elongation factor Ts, mitochondrial K02357 tsf; elongation factor Ts
D 116406430 tufm; elongation factor Tu, mitochondrial K02358 tuf; elongation factor Tu
D 100492326 gfm2; ribosome-releasing factor 2, mitochondrial isoform X2 K02355 fusA; elongation factor G
D 100494046 gfm1; elongation factor G, mitochondrial K02355 fusA; elongation factor G
D 549783 mterf1; transcription termination factor 1, mitochondrial K15031 MTERF; mitochondrial transcription termination factor family protein
D 100485703 mterf2; transcription termination factor 2, mitochondrial K15031 MTERF; mitochondrial transcription termination factor family protein
D 100379954 mterf4; transcription termination factor 4, mitochondrial K15031 MTERF; mitochondrial transcription termination factor family protein
D 394691 mterf3; transcription termination factor 3, mitochondrial isoform X2 K15031 MTERF; mitochondrial transcription termination factor family protein
D 100489624 guf1; translation factor GUF1, mitochondrial K21594 GUF1; translation factor GUF1, mitochondrial [EC:3.6.5.-]
C RNase MRP
D 101732380 pop1; ribonucleases P/MRP protein subunit POP1 isoform X2 K01164 POP1; ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5]
D 550006 pop4; ribonuclease P protein subunit p29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D 779510 pop5; ribonuclease P/MRP protein subunit POP5 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D 549338 rpp30; ribonuclease P protein subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D 100037866 pop7; uncharacterized protein LOC100037866 K14527 RPP20; ribonuclease P/MRP protein subunit RPP20 [EC:3.1.26.5]
D 100135176 rpp25l; uncharacterized protein LOC100135176 K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 100496900 rpp25; ribonuclease P protein subunit p25 K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 100379676 rpp38; ribonuclease P protein subunit p38 K14523 RPP38; ribonucleases P/MRP protein subunit RPP38 [EC:3.1.26.5]
D 779871 rpp40; ribonuclease P protein subunit p40 K14530 RPP40; ribonucleases P/MRP protein subunit RPP40 [EC:3.1.26.5]
C Mitochondrial ribonuclease P
D 100124885 trmt10c; tRNA methyltransferase 10 homolog C precursor K17654 TRMT10C; mitochondrial ribonuclease P protein 1 [EC:2.1.1.-]
D 549265 hsd17b10; 3-hydroxyacyl-CoA dehydrogenase type-2 K08683 HSD17B10; 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxy-2-methylbutyryl-CoA dehydrogenase [EC:1.1.1.35 1.1.1.178]
D 100125795 prorp; mitochondrial ribonuclease P catalytic subunit K17655 MRPP3; mitochondrial ribonuclease P protein 3
C Other mitochondrial DNA transcription and translation factors
D 100496751 mss51; putative protein MSS51 homolog, mitochondrial K17656 MSS51; mitochondrial splicing suppressor protein 51
D 100485913 tefm; transcription elongation factor, mitochondrial K17658 TEFM; transcription elongation factor, mitochondrial
D 100135205 ptcd1; pentatricopeptide repeat-containing protein 1, mitochondrial K17710 PTCD1; pentatricopeptide repeat domain-containing protein 1
D 100489047 ptcd2; pentatricopeptide repeat-containing protein 2, mitochondrial isoform X1 K17711 PTCD2; pentatricopeptide repeat domain-containing protein 2
D 548397 ptcd3; pentatricopeptide repeat-containing protein 3, mitochondrial precursor K17659 PTCD3; pentatricopeptide repeat domain-containing protein 3
D 779538 dhx30; ATP-dependent RNA helicase DHX30 isoform X1 K13185 DHX30; ATP-dependent RNA helicase DHX30 [EC:5.6.2.6]
D 394930 uqcc1; ubiquinol-cytochrome c reductase complex assembly factor 1 K17662 CBP3; cytochrome b pre-mRNA-processing protein 3
D 100490998 afg1l; AFG1-like ATPase isoform X1 K18798 AFG1; peroxisome-assembly ATPase [EC:3.6.4.7]
D 594990 atp23; mitochondrial inner membrane protease ATP23 homolog K18156 ATP23; mitochondrial inner membrane protease ATP23 [EC:3.4.24.-]
D 100495688 supv3l1; ATP-dependent RNA helicase SUPV3L1, mitochondrial K17675 SUPV3L1; ATP-dependent RNA helicase SUPV3L1/SUV3 [EC:5.6.2.6]
D 779879 lactb2; endoribonuclease LACTB2 K16639 LACTB2; endoribonuclease LACTB2 [EC:3.1.27.-]
D 394504 slc25a4; ADP/ATP translocase 1 K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D 394508 slc25a5; ADP/ATP translocase 2 K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D 100379786 slc25a37; mitoferrin-1 K15113 SLC25A28_37; solute carrier family 25 (mitochondrial iron transporter), member 28/37
D 780354 slc25a28; mitoferrin-2 K15113 SLC25A28_37; solute carrier family 25 (mitochondrial iron transporter), member 28/37
D 548894 malsu1; mitochondrial assembly of ribosomal large subunit protein 1 K25803 MALSU1; mitochondrial assembly of ribosomal large subunit protein 1
D 100495069 eral1; GTPase Era, mitochondrial K03595 era; GTPase
D 448444 yars1; tyrosine--tRNA ligase, cytoplasmic K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 100494249 yars2; tyrosine--tRNA ligase, mitochondrial K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 548548 lars1; leucine--tRNA ligase, cytoplasmic K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 100379697 lars2; probable leucine--tRNA ligase, mitochondrial isoform X1 K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 100145033 dars2; aspartate--tRNA ligase, mitochondrial isoform X1 K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 493218 gars1; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D 395040 rars1; arginine--tRNA ligase, cytoplasmic K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 100488556 rars2; probable arginine--tRNA ligase, mitochondrial isoform X1 K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 780239 qrsl1; glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D 100486675 gatb; glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial isoform X1 K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D 100495297 gatc; glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D 100492805 mtpap; poly(A) RNA polymerase, mitochondrial K18060 MTPAP; poly(A) RNA polymerase, mitochondrial [EC:2.7.7.19]
D 100127874 mtg1; mitochondrial ribosome-associated GTPase 1 K19828 MTG1; mitochondrial GTPase 1
D 100488516 noa1; nitric oxide-associated protein 1 isoform X1 K19832 NOA1; nitric oxide-associated protein 1
D 100495345 nsun3; tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial K21969 NSUN3; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.-]
D 100493736 nsun4; 5-methylcytosine rRNA methyltransferase NSUN4 K21970 NSUN4; 5-methylcytosine rRNA methyltransferase NSUN4 [EC:2.1.1.-]
D 100380049 rpusd3; mitochondrial mRNA pseudouridine synthase RPUSD3 isoform X1 K22537 RPUSD3; mitochondrial RNA pseudouridine synthase RPUSD3 [EC:5.4.99.-]
D 734064 rpusd4; mitochondrial RNA pseudouridine synthase rpusd4 K22538 RPUSD4; mitochondrial RNA pseudouridine synthase RPUSD4 [EC:5.4.99.-]
D 493236 rcc1l; Williams-Beuren syndrome chromosomal region 16 protein K23495 RCC1L; RCC1-like G exchanging factor-like protein
D 779519 ngrn; neugrin K23496 NGRN; neugrin
D 496499 trub2; mitochondrial mRNA pseudouridine synthase Trub2 K23497 TRUB2; mitochondrial mRNA pseudouridine synthase TRUB2 [EC:5.4.99.-]
D 100488261 fastkd2; FAST kinase domain-containing protein 2, mitochondrial K18190 FASTKD2; FAST kinase domain-containing protein 2
D 101734452 c1h12orf65; probable peptide chain release factor C12orf65 homolog, mitochondrial K23498 COXPD7; peptide chain release factor
D 101733789 rmnd1; required for meiotic nuclear division protein 1 homolog K23499 RMND1; required for meiotic nuclear division protein 1
D 100337653 grsf1; G-rich sequence factor 1 K24984 GRSF1; G-rich sequence factor 1
D 100145263 mettl15; probable methyltransferase-like protein 15 K25876 METTL15; 12S rRNA N4-methylcytidine (m4C) methyltransferase [EC:2.1.1.-]
D 594885 c12orf10; UPF0160 protein MYG1, mitochondrial K25877 MYG1; MYG1 exonuclease [EC:3.1.-.-]
D 779478 mtres1; uncharacterized protein C6orf203 homolog K26186 MTRES1; mitochondrial transcription rescue factor 1
B Mitochondrial DNA replication factors
C Mitochondrial DNA polymerase
D 100488393 polg; DNA polymerase subunit gamma-1 K02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]
D 100493143 polg2; DNA polymerase subunit gamma-2, mitochondrial isoform X1 K02333 POLG2; DNA polymerase gamma 2
D 548674 primpol; DNA-directed primase/polymerase protein K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
C Mitochondrial DNA maintenance factors
D 549956 endog; endonuclease G, mitochondrial precursor K01173 ENDOG; endonuclease G, mitochondrial
D 100145685 mgme1; mitochondrial genome maintenance exonuclease 1 K19465 MGME1; mitochondrial genome maintenance exonuclease 1 [EC:3.1.-.-]
D 116410962 mitochondrial genome maintenance exonuclease 1-like K19465 MGME1; mitochondrial genome maintenance exonuclease 1 [EC:3.1.-.-]
D 100486077 exog; nuclease EXOG, mitochondrial K15050 EXOG; nuclease EXOG, mitochondrial
D 100491229 twnk; twinkle protein, mitochondrial K17680 PEO1; twinkle protein [EC:5.6.2.3]
D 549357 pif1; PIF1 5'-to-3' DNA helicase K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
C Other Mitochondrial DNA replication factors
D 780115 ssbp1; single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
D 407895 atad3a; ATPase family AAA domain-containing protein 3 K17681 ATAD3A_B; ATPase family AAA domain-containing protein 3A/B
D 779699 uqcc2; ubiquinol-cytochrome-c reductase complex assembly factor 2 K17682 MNF1; mitochondrial nucleoid factor 1
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AMitochondrial protein import machinery
B Endoplasmic reticulum membrane and cytosol
C ER-mitochondria encounter structure (ERMES) complex
C Other ER-memrane and cytosol factors
D 448048 dnaja2; dnaJ homolog subfamily A member 2 K09503 DNAJA2; DnaJ homolog subfamily A member 2
D 100492251 rhot1; mitochondrial Rho GTPase 1 isoform X1 K07870 RHOT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-]
D 100037899 hsp70; heat shock 70kDa protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D 779883 hspa1l; heat shock protein family A (Hsp70) member 1 like K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D 100496320 hspa8; heat shock cognate 71 kDa protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D 100485441 hspa1b; LOW QUALITY PROTEIN: heat shock 70 kDa protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D 100488052 hspa1a; heat shock cognate 71 kDa protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D 100101778 aipl1; aryl-hydrocarbon-interacting protein-like 1 K17767 AIP; AH receptor-interacting protein
D 100124770 aip; AH receptor-interacting protein K17767 AIP; AH receptor-interacting protein
B Outer membrane
C Transporter outer membrane (TOM) complex
D 394730 tomm40; mitochondrial import receptor subunit TOM40 homolog K11518 TOM40; mitochondrial import receptor subunit TOM40
D 100496551 tomm40l; mitochondrial import receptor subunit TOM40B isoform X2 K11518 TOM40; mitochondrial import receptor subunit TOM40
D 100125169 tomm70; mitochondrial import receptor subunit TOM70 K17768 TOM70; mitochondrial import receptor subunit TOM70
D 734118 tomm22; mitochondrial import receptor subunit TOM22 homolog K17769 TOM22; mitochondrial import receptor subunit TOM22
D 448537 tomm20; mitochondrial import receptor subunit TOM20 homolog K17770 TOM20; mitochondrial import receptor subunit TOM20
D 549968 tomm7; mitochondrial import receptor subunit TOM7 homolog K17771 TOM7; mitochondrial import receptor subunit TOM7
D 100488986 tomm6; mitochondrial import receptor subunit TOM6 homolog K17772 TOM6; mitochondrial import receptor subunit TOM6
D 100380083 tomm5; mitochondrial import receptor subunit TOM5 homolog K17773 TOM5; mitochondrial import receptor subunit TOM5
C TOB/SAM complex
D 394743 samm50; sorting and assembly machinery component 50 homolog K07277 SAM50; outer membrane protein insertion porin family
C Porin
D 549246 vdac1; voltage-dependent anion-selective channel protein 1 K05862 VDAC1; voltage-dependent anion channel protein 1
D 548947 vdac2; voltage-dependent anion-selective channel protein 2 K15040 VDAC2; voltage-dependent anion channel protein 2
D 496695 vdac3; voltage-dependent anion-selective channel protein 3 K15041 VDAC3; voltage-dependent anion channel protein 3
C ERMES complex
C Other outer membrane factor
D 100493350 mtx3; metaxin-3 isoform X1 K17776 MTX; metaxin
D 549501 mtx1; metaxin 1 K17776 MTX; metaxin
D 447951 mtx2; metaxin-2 K17776 MTX; metaxin
D 734140 myo19; unconventional myosin-XIX K25838 MYO19; myosin XIX
D 100487963 mtarc1; MOSC domain-containing protein 1, mitochondrial-like K27318 MTARC; mitochondrial amidoxime-reducing component [EC:1.7.-.-]
D 100488668 mitochondrial amidoxime-reducing component 1 isoform X1 K27318 MTARC; mitochondrial amidoxime-reducing component [EC:1.7.-.-]
B Inter membrane space
C Transporter inner membrane (TIM) 9/10 complex
D 100135139 timm9; mitochondrial import inner membrane translocase subunit Tim9 K17777 TIM9; mitochondrial import inner membrane translocase subunit TIM9
D 394912 timm10; mitochondrial import inner membrane translocase subunit Tim10 K17778 TIM10; mitochondrial import inner membrane translocase subunit TIM10
D 100124896 timm10b; translocase of inner mitochondrial membrane 10 homolog B K17779 TIM10B; mitochondrial import inner membrane translocase subunit TIM10B
C TIM8/13 complex
D 549853 timm8b; mitochondrial import inner membrane translocase subunit Tim8 B K17780 TIM8; mitochondrial import inner membrane translocase subunit TIM8
D 100488371 timm8a; mitochondrial import inner membrane translocase subunit Tim8 A isoform X1 K17780 TIM8; mitochondrial import inner membrane translocase subunit TIM8
D 734099 timm13; mitochondrial import inner membrane translocase subunit Tim13 K17781 TIM13; mitochondrial import inner membrane translocase subunit TIM13
C Mitochondrial intermembrane space assembly (MIA) complex
D 394473 chchd4; mitochondrial intermembrane space import and assembly protein 40 K17782 MIA40; mitochondrial intermembrane space import and assembly protein 40
D 100488306 gfer; FAD-linked sulfhydryl oxidase ALR K17783 ERV1; mitochondrial FAD-linked sulfhydryl oxidase [EC:1.8.3.2]
B Inner mambrane
C MICOS complex
D 100135143 micos10; MICOS complex subunit MIC10 K17784 MICOS10; MICOS complex subunit MIC10
D 100489420 immt; MICOS complex subunit MIC60 isoform X1 K17785 IMMT; MICOS complex subunit MIC60
D 100489521 micos13; MICOS complex subunit MIC13 K24624 MICOS13; MICOS complex subunit MIC13
D 448247 chchd3; MICOS complex subunit MIC19 K17563 CHCHD3; MICOS complex subunit MIC19
D 548383 chchd6; MICOS complex subunit mic25 isoform X1 K17564 CHCHD6; MICOS complex subunit MIC25
D 100125130 apoo; MICOS complex subunit MIC26 K24625 APOO; MICOS complex subunit MIC26
D 100216278 apool; MICOS complex subunit MIC27 K24626 APOOL; MICOS complex subunit MIC27
C MICOS complex (yeast)
D 100135143 micos10; MICOS complex subunit MIC10 K17784 MICOS10; MICOS complex subunit MIC10
D 100489420 immt; MICOS complex subunit MIC60 isoform X1 K17785 IMMT; MICOS complex subunit MIC60
C TIM22 complex
D 496870 timm22; mitochondrial import inner membrane translocase subunit Tim22 K17790 TIM22; mitochondrial import inner membrane translocase subunit TIM22
C TIM23 complex
D 496463 timm23; mitochondrial import inner membrane translocase subunit Tim23 K17794 TIM23; mitochondrial import inner membrane translocase subunit TIM23
D 496605 timm17a; mitochondrial import inner membrane translocase subunit Tim17-A K17795 TIM17; mitochondrial import inner membrane translocase subunit TIM17
D 779691 timm17b; translocase of inner mitochondrial membrane 17 homolog B K17795 TIM17; mitochondrial import inner membrane translocase subunit TIM17
D 549225 timm21; mitochondrial import inner membrane translocase subunit Tim21 K17796 TIM21; mitochondrial import inner membrane translocase subunit TIM21
D 100145004 timm50; mitochondrial import inner membrane translocase subunit TIM50 K17496 TIM50; mitochondrial import inner membrane translocase subunit TIM50
C Mitochondrial calcium uniporter complex
D 100170451 mcu; calcium uniporter protein, mitochondrial K20858 MCU; calcium uniporter protein, mitochondrial
D 100127574 micu1; calcium uptake protein 1, mitochondrial K22827 MICU1; calcium uptake protein 1, mitochondrial
D 100486652 micu2; calcium uptake protein 2, mitochondrial K22828 MICU2; calcium uptake protein 2, mitochondrial
D 100145024 mcub; calcium uniporter regulatory subunit MCUb, mitochondrial K22829 MCUB; calcium uniporter regulatory subunit MCUb, mitochondrial
D 496604 smdt1; essential MCU regulator, mitochondrial precursor K22830 SMDT1; essential MCU regulator, mitochondrial
D 780306 mcur1; mitochondrial calcium uniporter regulator 1 K22137 MCUR1; mitochondrial calcium uniporter regulator 1
C Other inner membrane factors
D 780254 letm1; mitochondrial proton/calcium exchanger protein precursor K17800 LETM1; LETM1 and EF-hand domain-containing protein 1, mitochondrial
D 549343 immp1l; mitochondrial inner membrane protease subunit 1 K09647 IMP1; mitochondrial inner membrane protease subunit 1 [EC:3.4.21.-]
D 100488092 immp2l; mitochondrial inner membrane protease subunit 2 isoform X1 K09648 IMP2; mitochondrial inner membrane protease subunit 2 [EC:3.4.21.-]
D 394682 tmem126a; transmembrane protein 126A K18157 TMEM126A; transmembrane protein 126A
D 448739 mpc1; mitochondrial pyruvate carrier 1 K22138 MPC1; mitochondrial pyruvate carrier 1
D 549449 mpc2; mitochondrial pyruvate carrier 2 K22139 MPC2; mitochondrial pyruvate carrier 2
D 100379881 chchd10; coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial K22759 CHCHD10; coiled-coil-helix-coiled-coil-helix domain-containing protein 10
B Matrix
C MMC/PAM proteins
D 100145471 timm44; mitochondrial import inner membrane translocase subunit TIM44 K17804 TIM44; mitochondrial import inner membrane translocase subunit TIM44
D 407910 hspa9; stress-70 protein, mitochondrial K04043 dnaK; molecular chaperone DnaK
D 548933 grpel1; grpE protein homolog 1, mitochondrial K03687 GRPE; molecular chaperone GrpE
D 100216254 grpel2; grpE protein homolog 2, mitochondrial K03687 GRPE; molecular chaperone GrpE
D 549696 dnajc19; mitochondrial import inner membrane translocase subunit TIM14 K09539 DNAJC19; DnaJ homolog subfamily C member 19
D 447952 pam16; mitochondrial import inner membrane translocase subunit tim16 K17805 PAM16; mitochondrial import inner membrane translocase subunit TIM16
C Other matrix factors
D 100379912 pmpca; mitochondrial-processing peptidase subunit alpha K01412 PMPCA; mitochondrial-processing peptidase subunit alpha [EC:3.4.24.64]
D 733923 pmpcb; mitochondrial-processing peptidase subunit beta K17732 PMPCB; mitochondrial-processing peptidase subunit beta [EC:3.4.24.64]
D 100497804 mipep; mitochondrial intermediate peptidase isoform X2 K01410 MIPEP; mitochondrial intermediate peptidase [EC:3.4.24.59]
D 100124945 hspd1; 60 kDa heat shock protein, mitochondrial K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D 448701 hspe1; 10 kDa heat shock protein, mitochondrial K04078 groES; chaperonin GroES
D 100145451 dnaja3; dnaJ homolog subfamily A member 3, mitochondrial K09504 DNAJA3; DnaJ homolog subfamily A member 3
D 100379779 tamm41; phosphatidate cytidylyltransferase, mitochondrial K17807 TAM41; mitochondrial translocator assembly and maintenance protein 41
D 779561 dnlz; DNL-type zinc finger protein K17808 ZIM17; mitochondrial protein import protein ZIM17
D 448221 ethe1; persulfide dioxygenase ETHE1, mitochondrial K17725 ETHE1; sulfur dioxygenase [EC:1.13.11.18]
D 549852 poldip2; polymerase delta-interacting protein 2 K17809 POLDIP2; polymerase delta-interacting protein 2
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AMitochondrial quality control factors
B Regulator of mitochondrial biogenesis
C Ubiquitas transcription factors
D 407934 creb1; cyclic AMP-responsive element-binding protein 1 K05870 CREB1; cyclic AMP-responsive element-binding protein 1
D 100492326 gfm2; ribosome-releasing factor 2, mitochondrial isoform X2 K02355 fusA; elongation factor G
D 100494046 gfm1; elongation factor G, mitochondrial K02355 fusA; elongation factor G
D 394744 sp1; transcription factor Sp1 K04684 SP1; transcription factor Sp1
D 100126440 yy1; transcriptional repressor protein YY1 K09201 YY; transcription factor YY
D 493213 gabpb1; GA-binding protein subunit beta-1 K09454 GABPB; GA-binding protein transcription factor, beta
D 733936 gabpb2; GA-binding protein subunit beta-2 K09454 GABPB; GA-binding protein transcription factor, beta
D 100135718 tfam; transcription factor A, mitochondrial K11830 TFAM; transcription factor A, mitochondrial
C Nuclear respiratory factors
D 100488083 nrf1; nuclear respiratory factor 1 isoform X1 K11831 NRF1; nuclear respiratory factor 1
D 493217 nfe2l2; nuclear factor erythroid 2-related factor 2 K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
D 100135413 mt4; metallothionein 4 K14739 MT1_2; metallothionein 1/2
D 100495370 metallothionein-like K14739 MT1_2; metallothionein 1/2
D 116410391 metallothionein-like K14739 MT1_2; metallothionein 1/2
D 100488960 metallothionein K14741 MT4; metallothionein 4
C Coactivators
D 100491667 ppargc1a; peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1 K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
D 100488947 ppargc1b; peroxisome proliferator-activated receptor gamma coactivator 1-beta K17962 PPARGC1B; peroxisome proliferator-activated receptor gamma coactivator 1-beta
D 100488852 pprc1; peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform X1 K17963 PPRC1; peroxisome proliferator-activated receptor gamma coactivator-related protein 1
D 100036611 crtc1; CREB-regulated transcription coactivator 1 isoform X1 K15309 CRTC1; CREB-regulated transcription coactivator 1
D 100101677 crebbp; CREB-binding protein K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
D 734023 ep300; histone acetyltransferase p300 isoform X4 K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
C Proteins involved in Fe-S cluster biogenesis
D 100485815 nfs1; cysteine desulfurase, mitochondrial K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D 394688 iscu; iron-sulfur cluster assembly enzyme ISCU, mitochondrial K22068 ISCU; iron-sulfur cluster assembly enzyme ISCU, mitochondrial
D 100379678 lyrm4; LYR motif-containing protein 4 K22069 LYRM4; LYR motif-containing protein 4
D 100497789 fxn; frataxin, mitochondrial isoform X2 K19054 FXN; frataxin [EC:1.16.3.1]
D 100379765 fdx1; adrenodoxin K22070 FDX1; ferredoxin-1, mitochondrial
D 100145258 fdx2; ferredoxin-2, mitochondrial K22071 FDX2; ferredoxin-2, mitochondrial
D 100498263 adrenodoxin K22071 FDX2; ferredoxin-2, mitochondrial
D 100158651 fdxr; NADPH:adrenodoxin oxidoreductase, mitochondrial precursor K18914 FDXR; adrenodoxin-NADP+ reductase [EC:1.18.1.6]
D 407910 hspa9; stress-70 protein, mitochondrial K04043 dnaK; molecular chaperone DnaK
D 779876 hscb; iron-sulfur cluster co-chaperone protein HscB, mitochondrial K04082 hscB; molecular chaperone HscB
D 100124924 sil1; nucleotide exchange factor SIL1 K14001 SIL1; nucleotide exchange factor SIL1
D 448300 glrx5; glutaredoxin-related protein 5, mitochondrial K07390 grxD; monothiol glutaredoxin
D 100379677 isca1; iron-sulfur cluster assembly 1 homolog, mitochondrial isoform X1 K22063 ISCA1; iron-sulfur cluster assembly 1
D 100135112 isca2; iron-sulfur cluster assembly 2 homolog, mitochondrial K22072 ISCA2; iron-sulfur cluster assembly 2
D 100489125 iba57; putative transferase CAF17, mitochondrial isoform X1 K22073 IBA57; transferase CAF17, mitochondrial [EC:2.1.-.-]
D 779809 nfu1; NFU1 iron-sulfur cluster scaffold homolog, mitochondrial K22074 NFU1; NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
D 100170577 bola1; bolA-like protein 1 K22066 BOLA1; BolA-like protein 1
D 733564 bola3; bolA-like protein 3 K22075 BOLA3; BolA-like protein 3
D 100216274 sfxn3; sideroflexin-3 K23500 SFXN1_3; sideroflexin-1/3
D 548998 sfxn1; sideroflexin-1 K23500 SFXN1_3; sideroflexin-1/3
D 496514 sfxn2; sideroflexin-2 K23501 SFXN2; sideroflexin-2
D 100487071 sfxn4; sideroflexin-4 isoform X1 K23502 SFXN4; sideroflexin-4
D 448290 sfxn5; sideroflexin-5 K23503 SFXN5; sideroflexin-5
C Other regulator of mitochondrial biogenesis
D 100490391 cpt1a; carnitine O-palmitoyltransferase 1, liver isoform isoform X2 K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
D 100135089 cpt1al; carnitine O-palmitoyltransferase 1, brain isoform K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
D 780223 cpt1b; carnitine O-palmitoyltransferase 1, muscle isoform K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
D 100493977 dhtkd1; probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial isoform X1 K15791 DHKTD1; 2-oxoadipate dehydrogenase E1 component [EC:1.2.4.-]
D 100490265 fbxl4; F-box/LRR-repeat protein 4 K10270 FBXL4; F-box and leucine-rich repeat protein 4
D 100485535 hcfc1; host cell factor 1 isoform X1 K14966 HCFC1; host cell factor 1
D 100127587 hcfc2; host cell factor 2 isoform X2 K27390 HCFC2; host cell factor 2
D 493287 htt; huntingtin isoform X2 K04533 HD; huntingtin
D 780213 esrra; steroid hormone receptor ERR1 K08552 NR3B1; estrogen-related receptor alpha
D 100494008 esrrb; steroid hormone receptor ERR2 K08553 NR3B2; estrogen-related receptor beta
D 100101684 esrrg; estrogen-related receptor gamma K08554 NR3B3; estrogen-related receptor gamma
D 100488364 esrrgr; estrogen-related receptor gamma isoform X1 K08554 NR3B3; estrogen-related receptor gamma
D 100037834 nrip1; nuclear receptor-interacting protein 1 K17965 NRIP1; nuclear receptor-interacting protein 1
D 100145520 prkaa1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D 100216099 prkaa2; 5'-AMP-activated protein kinase catalytic subunit alpha-2 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D 100492505 lonp1; lon protease homolog, mitochondrial K08675 PRSS15; ATP-dependent Lon protease [EC:3.4.21.53]
D 100145679 sirt1; NAD-dependent protein deacetylase sirtuin-1 K11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
D 101730273 serac1; protein SERAC1 K23504 SERAC1; protein SERAC1
D 116406734 uxt; protein UXT K26537 UXT; protein UXT
D 101732869 perm1; PGC-1 and ERR-induced regulator in muscle protein 1 K26738 PERM1; PGC-1 and ERR-induced regulator in muscle protein 1
B Mitochondrial respiratory chain complex assembly factors
C Complex-I assembly factors
D 549907 ndufaf1; complex I intermediate-associated protein 30, mitochondrial K18159 NDUFAF1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1
D 100489348 ndufaf2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 K18160 NDUFAF2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2
D 448535 ndufaf3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 K09008 NDUFAF3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3
D 100216234 ndufaf4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 K18161 NDUFAF4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4
D 549152 ndufaf5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 K18162 NDUFAF5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 [EC:2.1.1.-]
D 100135115 ndufaf6; NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform X1 K18163 NDUFAF6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 6
D 548899 ndufaf7; protein arginine methyltransferase NDUFAF7, mitochondrial precursor K18164 NDUFAF7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 7
D 779865 ecsit; evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial precursor K04405 ECSIT; evolutionarily conserved signaling intermediate in Toll pathway
D 548505 acad9; acyl-CoA dehydrogenase family member 9, mitochondrial K15980 ACAD9; acyl-CoA dehydrogenase family member 9 [EC:1.3.99.-]
D 549327 nubpl; iron-sulfur protein NUBPL K03593 mrp; ATP-binding protein involved in chromosome partitioning
D 100125144 foxred1; FAD-dependent oxidoreductase domain-containing protein 1 K18166 FOXRED1; FAD-dependent oxidoreductase domain-containing protein 1
D 548828 rtn4ip1; reticulon-4-interacting protein 1, mitochondrial K23164 RTN4IP1; reticulon-4-interacting protein 1, mitochondrial
D 100145717 timmdc1; uncharacterized protein LOC100145717 K23505 TIMMDC1; complex I assembly factor TIMMDC1
C Complex-II assembly factors
D 101732873 sdhaf1; succinate dehydrogenase assembly factor 1, mitochondrial K18167 SDHAF1; succinate dehydrogenase assembly factor 1
D 100497541 sdhaf2; succinate dehydrogenase assembly factor 2, mitochondrial K18168 SDHAF2; succinate dehydrogenase assembly factor 2
C Complex-III assembly factors
D 549619 bcs1l; BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone K08900 BCS1; mitochondrial chaperone BCS1
D 100485992 ttc19; tetratricopeptide repeat protein 19, mitochondrial isoform X1 K18169 TTC19; tetratricopeptide repeat protein 19, mitochondrial
D 100124785 lyrm7; complex III assembly factor LYRM7 K18170 LYRM7; complex III assembly factor LYRM7
D 394930 uqcc1; ubiquinol-cytochrome c reductase complex assembly factor 1 K17662 CBP3; cytochrome b pre-mRNA-processing protein 3
D 779699 uqcc2; ubiquinol-cytochrome-c reductase complex assembly factor 2 K17682 MNF1; mitochondrial nucleoid factor 1
D 106557438 uqcc3; ubiquinol-cytochrome-c reductase complex assembly factor 3 K23165 UQCC3; ubiquinol-cytochrome-c reductase complex assembly factor 3
D 733536 c16orf91; protein ccsmst1 precursor K27339 UQCC4; ubiquinol-cytochrome c reductase complex assembly factor 4
D 116410490 smim4; small integral membrane protein 4 K27340 UQCC5; ubiquinol-cytochrome c reductase complex assembly factor 5
D 100380143 c12orf73; uncharacterized protein C12orf73 homolog K27341 UQCC6; ubiquinol-cytochrome c reductase complex assembly factor 6
D 101734156 stmp1; short transmembrane mitochondrial protein 1 K27319 STMP1; short transmembrane mitochondrial protein 1
C Complex-IV assembly factors
D 100135408 cmc1; COX assembly mitochondrial protein homolog K18171 CMC1; COX assembly mitochondrial protein 1
D 733988 cmc2; COX assembly mitochondrial protein 2 homolog K18172 CMC2; COX assembly mitochondrial protein 2
D 100492393 coa1; cytochrome c oxidase assembly factor 1 homolog K18173 COA1; cytochrome c oxidase assembly factor 1
D 100135386 ccdc56; coiled-coil domain containing 56 K18175 CCDC56; cytochrome c oxidase assembly factor 3, animal type
D 733917 coa5; cytochrome c oxidase assembly factor 5 K18178 COA5; cytochrome c oxidase assembly factor 5
D 100135157 coa6; cytochrome c oxidase assembly factor 6 K18179 COA6; cytochrome c oxidase assembly factor 6
D 779859 coa7; cytochrome c oxidase assembly factor 7 K18180 COA7; cytochrome c oxidase assembly factor 7
D 100145039 cox10; cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 K02257 COX10; heme o synthase [EC:2.5.1.141]
D 100491545 cox11; cytochrome c oxidase assembly protein COX11, mitochondrial K02258 COX11; cytochrome c oxidase assembly protein subunit 11
D 101731814 cox14; cytochrome c oxidase assembly protein COX14 homolog K18181 COX14; cytochrome c oxidase assembly factor 14
D 100486044 cox15; cytochrome c oxidase assembly protein COX15 homolog K02259 COX15; heme a synthase [EC:1.17.99.9]
D 100379706 cox16; cytochrome c oxidase assembly protein COX16 homolog, mitochondrial K18182 COX16; cytochrome c oxidase assembly protein subunit 16
D 779703 cox17; COX17 homolog, cytochrome c oxidase assembly protein K02260 COX17; cytochrome c oxidase assembly protein subunit 17
D 549087 cox18; cytochrome c oxidase assembly factor COX18 K17797 COX18; mitochondrial inner membrane protein COX18
D 100145542 cox19; cytochrome c oxidase assembly protein COX19 K18183 COX19; cytochrome c oxidase assembly protein subunit 19
D 100497666 cox20; cytochrome c oxidase assembly protein COX20, mitochondrial K18184 COX20; cytochrome c oxidase assembly protein subunit 20
D 100496751 mss51; putative protein MSS51 homolog, mitochondrial K17656 MSS51; mitochondrial splicing suppressor protein 51
D 100493963 pet100; protein PET100 homolog, mitochondrial K18186 PET100; protein PET100, animal type
D 100127562 oxa1l; mitochondrial inner membrane protein OXA1L K03217 yidC; YidC/Oxa1 family membrane protein insertase
D 549543 surf1; surfeit locus protein 1 precursor K14998 SURF1; surfeit locus 1 family protein
D 100494754 sco1; protein SCO1 homolog, mitochondrial isoform X1 K07152 SCO1; protein SCO1
D 100497895 sco2; protein SCO2 homolog, mitochondrial isoform X2 K23755 SCO2; protein SCO2
D 100135399 taco1; translational activator of cytochrome c oxidase 1 K18189 TACO1; translational activator of cytochrome c oxidase 1
D 734062 lrpprc; leucine-rich PPR motif-containing protein, mitochondrial precursor K17964 LRPPRC; leucine-rich PPR motif-containing protein, mitochondrial
D 100380039 coa8; cytochrome c oxidase assembly factor 8 K23506 APOPT1; apoptogenic protein 1
D 101734156 stmp1; short transmembrane mitochondrial protein 1 K27319 STMP1; short transmembrane mitochondrial protein 1
D 116410490 smim4; small integral membrane protein 4 K27340 UQCC5; ubiquinol-cytochrome c reductase complex assembly factor 5
D 100158607 tmem223; transmembrane protein 223 K27342 TMEM223; transmembrane protein 223
C Complex-V assembly factors
D 493432 atpaf1; ATP synthase mitochondrial F1 complex assembly factor 1 precursor K07555 ATPeAF1; ATP synthase mitochondrial F1 complex assembly factor 1
D 394633 atpaf2; ATP synthase mitochondrial F1 complex assembly factor 2 precursor K07556 ATPeAF2; ATP synthase mitochondrial F1 complex assembly factor 2
D 100380062 tmem70; transmembrane protein 70, mitochondrial K17966 TMEM70; transmembrane protein 70, mitochondrial
D 101730293 atp5md; ATP synthase membrane subunit DAPIT, mitochondrial K18194 USMG5; up-regulated during skeletal muscle growth protein 5
B Mitochondrial dynamics
C Fission and Fusion factors
D 548943 mfn1; mitofusin-1 K21356 MFN1; mitofusin 1 [EC:3.6.5.-]
D 549268 mfn2; mitofusin-2 K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
D 100145638 opa1; dynamin-like 120 kDa protein, mitochondrial K17079 OPA1; optic atrophy protein 1 [EC:3.6.5.5]
D 100485565 opa3; optic atrophy 3 protein K23166 OPA3; optic atrophy 3 protein
D 549022 triap1; TP53-regulated inhibitor of apoptosis 1 K17968 TRIAP1; TRIAP1/MDM35 family protein
D 100036610 parl; presenilins-associated rhomboid-like protein, mitochondrial K09650 PARL; rhomboid-like protein [EC:3.4.21.105]
D 108645783 bak1; bcl-2 homologous antagonist/killer isoform X1 K14021 BAK; Bcl-2 homologous antagonist/killer
D 394793 bax; apoptosis regulator BAX K02159 BAX; apoptosis regulator BAX
D 100494576 dnm1l; dynamin-1-like protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D 100170430 fis1; mitochondrial fission 1 protein K17969 FIS1; mitochondrial fission 1 protein
D 100125978 sumo3; small ubiquitin-related modifier 3 K12160 SUMO; small ubiquitin-related modifier
D 549160 sumo2; small ubiquitin-related modifier 2 precursor K12160 SUMO; small ubiquitin-related modifier
D 448691 sumo1; small ubiquitin-related modifier 1 precursor K12160 SUMO; small ubiquitin-related modifier
D 548826 sh3glb1; endophilin-B1 K11248 SH3GLB1; endophilin-B1
D 394719 mtch2; mitochondrial carrier homolog 2 K17885 MTCH; mitochondrial carrier
D 100379850 mff; mitochondrial fission factor isoform X1 K22076 MFF; mitochondrial fission factor
D 100490264 gdap1; ganglioside-induced differentiation-associated protein 1 K22077 GDAP1; ganglioside-induced differentiation-associated protein 1
D 779687 gdap1l1; ganglioside-induced differentiation-associated protein 1-like 1 K22077 GDAP1; ganglioside-induced differentiation-associated protein 1
D 493196 vat1; synaptic vesicle membrane protein VAT-1 homolog K23167 VAT1; synaptic vesicle membrane protein VAT-1
D 100144671 mief2; mitochondrial dynamics protein MID49 K23507 MIEF1_2; mitochondrial dynamics protein MID51/49
D 595090 mief1; mitochondrial dynamics protein MID51 K23507 MIEF1_2; mitochondrial dynamics protein MID51/49
D 549629 pld6; mitochondrial cardiolipin hydrolase K16862 PLD6; mitochondrial cardiolipin hydrolase [EC:3.1.4.-]
D 100125001 miga2; mitoguardin 2 K27289 MIGA; mitoguardin
C Actin cytoskeleton organization
D 394957 actg1; actin, cytoplasmic 2 K05692 ACTB_G1; actin beta/gamma 1
D 407952 actb; actin, cytoplasmic 1 K05692 ACTB_G1; actin beta/gamma 1
D 394715 naa20; N-alpha-acetyltransferase 20 K17972 NAA20; N-terminal acetyltransferase B complex catalytic subunit [EC:2.3.1.254]
D 100038044 naa25; N-alpha-acetyltransferase 25, NatB auxiliary subunit K17973 NAA25; N-terminal acetyltransferase B complex non-catalytic subunit
C Mitochondrial movement
D 394635 phb; prohibitin K17080 PHB1; prohibitin 1
D 549305 phb2; prohibitin-2 K17081 PHB2; prohibitin 2
D 100125787 ktn1; kinectin K17975 KTN1; kinectin
C Retention of mitochondria
D 100494576 dnm1l; dynamin-1-like protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D 100379760 myo5b; unconventional myosin-Vb isoform X1 K10357 MYO5; myosin V
D 100495210 myo5c; unconventional myosin-Vc isoform X3 K10357 MYO5; myosin V
D 100495365 myo5a; unconventional myosin-Va isoform X14 K10357 MYO5; myosin V
D 594971 xiap; E3 ubiquitin-protein ligase XIAP K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
D 549035 diablo; diablo homolog, mitochondrial precursor K10522 DIABLO; diablo
C Morphogenesis factors
D 100127563 snx25; sorting nexin-25 isoform X1 K17887 SNX25; sorting nexin-25
D 100492251 rhot1; mitochondrial Rho GTPase 1 isoform X1 K07870 RHOT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-]
D 100489420 immt; MICOS complex subunit MIC60 isoform X1 K17785 IMMT; MICOS complex subunit MIC60
D 100124873 mtfp1; mitochondrial fission process protein 1 K17981 MTFP1; mitochondrial fission process protein 1
D 548756 dap3; 28S ribosomal protein S29, mitochondrial K17408 DAP3; small subunit ribosomal protein S29
D 100496333 nedd4; E3 ubiquitin-protein ligase NEDD4 isoform X4 K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
D 100127645 oxr1; oxidation resistance protein 1 K25437 OXR1; oxidation resistance protein 1
D 100145525 msto1; protein misato homolog 1 isoform X1 K27320 MSTO1; protein misato
B Mitophagy factors
C Autophagy-related proteins
D 780082 atg2b; autophagy-related protein 2 homolog B K17906 ATG2; autophagy-related protein 2
D 780111 atg2a; autophagy-related protein 2 homolog A K17906 ATG2; autophagy-related protein 2
D 496900 atg3; ubiquitin-like-conjugating enzyme ATG3 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
D 549373 atg4a; cysteine protease ATG4A K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D 493268 atg4c; cysteine protease ATG4C K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D 779919 atg4b; cysteine protease ATG4B K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D 734111 atg4d; cysteine protease ATG4D K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D 549199 atg5; autophagy protein 5 K08339 ATG5; autophagy-related protein 5
D 619357 becn1; beclin-1 K08334 BECN; beclin
D 100170158 atg7; ubiquitin-like modifier-activating enzyme ATG7 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D 496614 gabarapl1; GABA(A) receptor-associated protein like 1 K08341 GABARAP; GABA(A) receptor-associated protein
D 595040 gabarapl1; gamma-aminobutyric acid receptor-associated protein-like 1 K08341 GABARAP; GABA(A) receptor-associated protein
D 100125141 gabarapl2; gamma-aminobutyric acid receptor-associated protein-like 2 K08341 GABARAP; GABA(A) receptor-associated protein
D 100486160 atg9b; autophagy-related protein 9B K17907 ATG9; autophagy-related protein 9
D 100497686 atg9a; autophagy-related protein 9A K17907 ATG9; autophagy-related protein 9
D 100492117 atg10; ubiquitin-like-conjugating enzyme ATG10 isoform X2 K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
D 100493403 atg12; ubiquitin-like protein ATG12 K08336 ATG12; ubiquitin-like protein ATG12
D 100158656 atg14; beclin 1-associated autophagy-related key regulator K17889 ATG14L; beclin 1-associated autophagy-related key regulator
D 550097 atg16l1; autophagy-related protein 16 K17890 ATG16L1; autophagy-related protein 16-1
D 100485143 atg16l2; autophagy-related protein 16-2 isoform X1 K20868 ATG16L2; autophagy-related protein 16-2
D 100497399 wipi2; WD repeat domain phosphoinositide-interacting protein 2 isoform X2 K17908 WIPI1_2; autophagy-related protein 18
D 496656 wipi1; WD repeat domain phosphoinositide-interacting protein 1 K17908 WIPI1_2; autophagy-related protein 18
D 100496743 vacuolar protein 8 K08332 VAC8; vacuolar protein 8
C Parkin-dependent mechanism factors
D 100489964 rnf41; E3 ubiquitin-protein ligase NRDP1 isoform X1 K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
D 100488730 clec16a; protein CLEC16A isoform X2 K19513 CLEC16A; protein CLEC16A
D 100036610 parl; presenilins-associated rhomboid-like protein, mitochondrial K09650 PARL; rhomboid-like protein [EC:3.4.21.105]
D 493277 sqstm1; sequestosome-1 K14381 SQSTM1; sequestosome 1
D 394857 tax1bp1; tax1-binding protein 1 homolog K21347 TAX1BP1; Tax1-binding protein 1
D 448562 calcoco2; calcium-binding and coiled-coil domain-containing protein 2 K21348 CALCOCO2; calcium-binding and coiled-coil domain-containing protein 2
D 100497158 ambra1; activating molecule in BECN1-regulated autophagy protein 1 isoform X3 K17985 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1
C Parkin-independent mechanism factors
D 100125026 atg13; autophagy-related protein 13 K08331 ATG13; autophagy-related protein 13
D 100127200 ulk1; serine/threonine-protein kinase ULK1 K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
D 100487396 ulk2; serine/threonine-protein kinase ULK2 K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
D 100127640 rb1cc1; RB1-inducible coiled-coil protein 1 K17589 RB1CC1; RB1-inducible coiled-coil protein 1
D 595047 hsp90ab1; heat shock protein HSP 90-beta K04079 HSP90A; molecular chaperone HtpG
D 780222 hsp90aa1.2; heat shock protein 90kDa alpha (cytosolic), class A member 1, gene 2 K04079 HSP90A; molecular chaperone HtpG
D 549036 hsp90aa1.1; heat shock protein 90kDa alpha family class A member 1 K04079 HSP90A; molecular chaperone HtpG
D 548666 cdc37; hsp90 co-chaperone Cdc37 K09554 CDC37; cell division cycle protein 37
D 100038194 smurf2; E3 ubiquitin-protein ligase SMURF2 isoform X1 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
D 100491582 smurf1; E3 ubiquitin-protein ligase SMURF1 isoform X1 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
D 100126677 bnip3l; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like K15465 BNIP3L; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
D 100145592 fundc1; FUN14 domain-containing protein 1 K17986 FUNDC1; FUN14 domain-containing protein 1
C Other mitophagy factors
D 100145520 prkaa1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D 100216099 prkaa2; 5'-AMP-activated protein kinase catalytic subunit alpha-2 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D 394972 map1lc3b; microtubule-associated proteins 1A/1B light chain 3B K10435 MAP1LC; microtubule-associated protein 1 light chain
D 493344 map1lc3a; microtubule-associated proteins 1A/1B light chain 3A K10435 MAP1LC; microtubule-associated protein 1 light chain
D 733779 map1lc3c; microtubule-associated proteins 1A/1B light chain 3C K10435 MAP1LC; microtubule-associated protein 1 light chain
D 100496229 microtubule-associated proteins 1A/1B light chain 3C K10435 MAP1LC; microtubule-associated protein 1 light chain
D 100485564 nbr1; next to BRCA1 gene 1 protein isoform X1 K17987 NBR1; next to BRCA1 gene 1 protein
D 100135077 tecpr1; tectonin beta-propeller repeat-containing protein 1 K17988 TECPR1; tectonin beta-propeller repeat-containing protein 1
D 100487902 zfyve1l; zinc finger FYVE domain-containing protein 1 isoform X2 K17603 ZFYVE1; zinc finger FYVE domain-containing protein 1
D 100486687 zfyve1; zinc finger FYVE domain-containing protein 1 isoform X1 K17603 ZFYVE1; zinc finger FYVE domain-containing protein 1
D 100490454 coasy; bifunctional coenzyme A synthase K02318 COASY; phosphopantetheine adenylyltransferase / dephospho-CoA kinase [EC:2.7.7.3 2.7.1.24]
D 780118 pla2g6; 85/88 kDa calcium-independent phospholipase A2 isoform X1 K16343 PLA2G6; calcium-independent phospholipase A2 [EC:3.1.1.4]
D 448278 c19orf12; protein C19orf12 homolog K23168 MPAN; protein MPAN
D 100488697 uncharacterized protein LOC100488697 K23168 MPAN; protein MPAN
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 14, 2024