| |
KO |
 Eukaryotic type
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 SSBR (single strand breaks repair)
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DSBR (double strand breaks repair)
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HR (homologous recombination)
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MRN(MRX) complex
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BRCA1-core complex
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BRCA1-A complex
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BRCA1-B complex
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BRCA1-C complex
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BRCA complex
|
 672 BRCA1; BRCA1 DNA repair associated
675 BRCA2; BRCA2 DNA repair associated
79728 PALB2; partner and localizer of BRCA2
5888 RAD51; RAD51 recombinase
|
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K08775 BRCA2; breast cancer 2 susceptibility protein
K10897 PALB2; partner and localizer of BRCA2
K04482 RAD51; DNA repair protein RAD51
|
RecA family proteins
|
Rad52 family proteins
|
Rad54 family proteins
|
RecQ family DNA helicases
|
Bloom's syndrome complex (BTR)
|
RPA (replication factor A)
|
Protein phosphatase 4
|
AP-5 complex
|
SMC5-SMC6 complex
|
Other HR factors
|
NHEJ (non-homologous end-joining)
|
FA (Fanconi anemia) pathway
|
FA core complex
|
FA core complex binding factors
|
Bloom's syndrome complex (BTR)
|
FANCD2-I complex
|
Downstream FA components
|
672 BRCA1; BRCA1 DNA repair associated
675 BRCA2; BRCA2 DNA repair associated
83990 BRIP1; BRCA1 interacting helicase 1
79728 PALB2; partner and localizer of BRCA2
|
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K08775 BRCA2; breast cancer 2 susceptibility protein
K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
K10897 PALB2; partner and localizer of BRCA2
|
Other FA pathway factors
|
Other DSBR factors
|
TLS (translesion DNA synthesis) factors
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Check point factors
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Other factors with a suspected DNA repair function
|
|
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Prokaryotic type
|
DNA Repair and Recombination Proteins - Homo sapiens (human)