Ubiquitin System - Homo sapiens (human)

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     KO
 Ubiquitins and ubiquitin-like proteins
 
 Ubiquitin-activating enzymes (E1)
 
 Ubiquitin-conjugating enzymes (E2)
 
 Ubiquitin ligases (E3)
   HECT type E3
   U-box type E3
   Single Ring-finger type E3
   Atypical E3
   UBL E3 ligases
   Multi subunit Ring-finger type E3
     SCF complex
     Cul2 complex
     Cul3 complex
     Cul4 complex
     Cul5 complex
       Ring finger protein
       Cullin
       Adoptor protein
       Target recognizing subunit
         1154 CISH; cytokine inducible SH2 containing protein
         8651 SOCS1; suppressor of cytokine signaling 1
         8835 SOCS2; suppressor of cytokine signaling 2
         9021 SOCS3; suppressor of cytokine signaling 3
         122809 SOCS4; suppressor of cytokine signaling 4
         9655 SOCS5; suppressor of cytokine signaling 5
         30837 SOCS7; suppressor of cytokine signaling 7
         9306 SOCS6; suppressor of cytokine signaling 6
         51665 ASB1; ankyrin repeat and SOCS box containing 1
         51676 ASB2; ankyrin repeat and SOCS box containing 2
         51130 ASB3; ankyrin repeat and SOCS box containing 3
         100302652 GPR75-ASB3; GPR75-ASB3 readthrough
         51666 ASB4; ankyrin repeat and SOCS box containing 4
         140458 ASB5; ankyrin repeat and SOCS box containing 5
         140459 ASB6; ankyrin repeat and SOCS box containing 6
         140460 ASB7; ankyrin repeat and SOCS box containing 7
         140461 ASB8; ankyrin repeat and SOCS box containing 8
         140462 ASB9; ankyrin repeat and SOCS box containing 9
         136371 ASB10; ankyrin repeat and SOCS box containing 10
         140456 ASB11; ankyrin repeat and SOCS box containing 11
         142689 ASB12; ankyrin repeat and SOCS box containing 12
         79754 ASB13; ankyrin repeat and SOCS box containing 13
         142686 ASB14; ankyrin repeat and SOCS box containing 14
         142685 ASB15; ankyrin repeat and SOCS box containing 15
         92591 ASB16; ankyrin repeat and SOCS box containing 16
         127247 ASB17; ankyrin repeat and SOCS box containing 17
         401036 ASB18; ankyrin repeat and SOCS box containing 18
         26118 WSB1; WD repeat and SOCS box containing 1
         55884 WSB2; WD repeat and SOCS box containing 2
         80176 SPSB1; splA/ryanodine receptor domain and SOCS box containing 1
         92369 SPSB4; splA/ryanodine receptor domain and SOCS box containing 4
         84727 SPSB2; splA/ryanodine receptor domain and SOCS box containing 2
         90864 SPSB3; splA/ryanodine receptor domain and SOCS box containing 3
         57799 RAB40C; RAB40C, member RAS oncogene family
         282808 RAB40AL; RAB40A like
         142684 RAB40A; RAB40A, member RAS oncogene family
         10966 RAB40B; RAB40B, member RAS oncogene family
         10489 LRRC41; leucine rich repeat containing 41
         89970 RSPRY1; ring finger and SPRY domain containing 1
         122416 ANKRD9; ankyrin repeat domain 9
         122773 KLHDC1; kelch domain containing 1
K04701 CISH; cytokine inducible SH2-containing protein 
K04694 SOCS1; suppressor of cytokine signaling 1 
K04695 SOCS2; suppressor of cytokine signaling 2 
K04696 SOCS3; suppressor of cytokine signaling 3 
K04697 SOCS4; suppressor of cytokine signaling 4 
K04698 SOCS5; suppressor of cytokine signaling 5 
K04699 SOCS6_7; suppressor of cytokine signaling 6/7 
K04699 SOCS6_7; suppressor of cytokine signaling 6/7 
K10323 ASB1; ankyrin repeat and SOCS box protein 1 
K10324 ASB2; ankyrin repeat and SOCS box protein 2 
K10325 ASB3; ankyrin repeat and SOCS box protein 3 
K10325 ASB3; ankyrin repeat and SOCS box protein 3 
K10326 ASB4; ankyrin repeat and SOCS box protein 4 
K10327 ASB5; ankyrin repeat and SOCS box protein 5 
K10328 ASB6; ankyrin repeat and SOCS box protein 6 
K10329 ASB7; ankyrin repeat and SOCS box protein 7 
K10330 ASB8; ankyrin repeat and SOCS box protein 8 
K10331 ASB9; ankyrin repeat and SOCS box protein 9 
K10332 ASB10; ankyrin repeat and SOCS box protein 10 
K10333 ASB11; ankyrin repeat and SOCS box protein 11 
K10334 ASB12; ankyrin repeat and SOCS box protein 12 
K10335 ASB13; ankyrin repeat and SOCS box protein 13 
K10336 ASB14; ankyrin repeat and SOCS box protein 14 
K10337 ASB15; ankyrin repeat and SOCS box protein 15 
K10338 ASB16; ankyrin repeat and SOCS box protein 16 
K10339 ASB17; ankyrin repeat and SOCS box protein 17 
K10340 ASB18; ankyrin repeat and SOCS box protein 18 
K10341 WSB1; WD repeat and SOCS box-containing protein 1 
K10342 WSB2; WD repeat and SOCS box-containing protein 2 
K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4 
K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4 
K10344 SPSB2; SPRY domain-containing SOCS box protein 2 
K10345 SPSB3; SPRY domain-containing SOCS box protein 3 
K07928 RAB40; Ras-related protein Rab-40 
K07928 RAB40; Ras-related protein Rab-40 
K07928 RAB40; Ras-related protein Rab-40 
K07928 RAB40; Ras-related protein Rab-40 
K10347 LRRC41; leucine-rich repeat-containing protein 41 
K23332 RSPRY1; RING finger and SPRY domain-containing protein 1 
K25208 ANKRD9; ankyrin repeat domain-containing protein 9 
K25810 KLHDC1; kelch domain-containing protein 1 
     Cul7 complex
     Cul8 complex
     Cul9 complex
     APC/C
     BRCC complex
     KPC complex
     LUBAC complex
     CTLH complex
     ERAD complex
     LMBR1L-GP78-UBAC2 complex
     SLX5-SLX8 complex
     Multi subunit type E3 associated proteins
 
 Deubiquitinating enzyme (DUB)

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Last updated: April 5, 2024