Membrane Trafficking - Homo sapiens (human)

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     KO
 Exocytosis
 
 SNARE
 
 Endocytosis
   Clathrin-mediated endocytosis
     Clathrin
     Dynamin
     AP-2 complex
     Other core components
       115548 FCHO2; FCH and mu domain containing endocytic adaptor 2
       23149 FCHO1; FCH and mu domain containing endocytic adaptor 1
       29924 EPN1; epsin 1
       55040 EPN3; epsin 3
       22905 EPN2; epsin 2
       2060 EPS15; epidermal growth factor receptor pathway substrate 15
       58513 EPS15L1; epidermal growth factor receptor pathway substrate 15 like 1
       30011 SH3KBP1; SH3 domain containing kinase binding protein 1
       9892 SNAP91; synaptosome associated protein 91
       8301 PICALM; phosphatidylinositol binding clathrin assembly protein
       50618 ITSN2; intersectin 2
       6453 ITSN1; intersectin 1
       273 AMPH; amphiphysin
       274 BIN1; bridging integrator 1
       112574 SNX18; sorting nexin 18
       257364 SNX33; sorting nexin 33
       51429 SNX9; sorting nexin 9
       9829 DNAJC6; DnaJ heat shock protein family (Hsp40) member C6
       2580 GAK; cyclin G associated kinase
       3312 HSPA8; heat shock protein family A (Hsp70) member 8
       3303 HSPA1A; heat shock protein family A (Hsp70) member 1A
       3305 HSPA1L; heat shock protein family A (Hsp70) member 1 like
       3304 HSPA1B; heat shock protein family A (Hsp70) member 1B
       3310 HSPA6; heat shock protein family A (Hsp70) member 6
       3306 HSPA2; heat shock protein family A (Hsp70) member 2
K20042 FCHO; F-BAR domain only protein 
K20042 FCHO; F-BAR domain only protein 
K12471 EPN; epsin 
K12471 EPN; epsin 
K12471 EPN; epsin 
K12472 EPS15; epidermal growth factor receptor substrate 15 
K12472 EPS15; epidermal growth factor receptor substrate 15 
K12470 SH3KBP1; SH3 domain-containing kinase-binding protein 1 
K20043 SNAP91; clathrin coat assembly protein AP180 
K20044 PICALM; phosphatidylinositol-binding clathrin assembly protein 
K20045 ITSN; intersectin 
K20045 ITSN; intersectin 
K12562 AMPH; amphiphysin 
K12562 AMPH; amphiphysin 
K17923 SNX9_18_33; sorting nexin-9/18/33 
K17923 SNX9_18_33; sorting nexin-9/18/33 
K17923 SNX9_18_33; sorting nexin-9/18/33 
K09526 DNAJC6; DnaJ homolog subfamily C member 6 
K08855 GAK; cyclin G-associated kinase [EC:2.7.11.1] 
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8 
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8 
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8 
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8 
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8 
K26598 HSPA2; heat shock 70kDa protein 2 
     Low-density lipoprotein receptor (LDLR) family proteins
     LDLR adaptor proteins
     GPCR adaptor proteins
     Receptor tyrosine kinase (RTK) adaptor proteins
     Inositol 5-phosphatases
     Kinases
     Ubiquitin E3 ligases
     Others
   Lipid raft mediated endocytosis
   Phagocytosis
   Macropinocytosis
   Bin/Amphiphysin/Rvs (BAR) family proteins
     N-BAR proteins
     F-BAR proteins
       9322 TRIP10; thyroid hormone receptor interactor 10
       23048 FNBP1; formin binding protein 1
       54874 FNBP1L; formin binding protein 1 like
       115548 FCHO2; FCH and mu domain containing endocytic adaptor 2
       23149 FCHO1; FCH and mu domain containing endocytic adaptor 1
       23380 SRGAP2; SLIT-ROBO Rho GTPase activating protein 2
       57522 SRGAP1; SLIT-ROBO Rho GTPase activating protein 1
       9901 SRGAP3; SLIT-ROBO Rho GTPase activating protein 3
       393 ARHGAP4; Rho GTPase activating protein 4
       11252 PACSIN2; protein kinase C and casein kinase substrate in neurons 2
       29763 PACSIN3; protein kinase C and casein kinase substrate in neurons 3
       29993 PACSIN1; protein kinase C and casein kinase substrate in neurons 1
       9051 PSTPIP1; proline-serine-threonine phosphatase interacting protein 1
       9050 PSTPIP2; proline-serine-threonine phosphatase interacting protein 2
       89848 FCHSD1; FCH and double SH3 domains 1
       9873 FCHSD2; FCH and double SH3 domains 2
       2241 FER; FER tyrosine kinase
       2242 FES; FES proto-oncogene, tyrosine kinase
       115677 NOSTRIN; nitric oxide synthase trafficking
       8522 GAS7; growth arrest specific 7
K07196 TRIP10; thyroid hormone receptor interactor 10 
K20121 FNBP1; formin-binding protein 1 
K20121 FNBP1; formin-binding protein 1 
K20042 FCHO; F-BAR domain only protein 
K20042 FCHO; F-BAR domain only protein 
K07526 SRGAP; SLIT-ROBO Rho GTPase activating protein 
K07526 SRGAP; SLIT-ROBO Rho GTPase activating protein 
K07526 SRGAP; SLIT-ROBO Rho GTPase activating protein 
K20122 ARHGAP4; Rho GTPase-activating protein 4 
K20123 PACSIN; protein kinase C and casein kinase substrate in neurons protein 
K20123 PACSIN; protein kinase C and casein kinase substrate in neurons protein 
K20123 PACSIN; protein kinase C and casein kinase substrate in neurons protein 
K12804 PSTPIP1; proline-serine-threonine phosphatase interacting protein 1 
K20124 PSTPIP2; proline-serine-threonine phosphatase interacting protein 2 
K20125 FCHSD; F-BAR and double SH3 domains protein 
K20125 FCHSD; F-BAR and double SH3 domains protein 
K08889 FER; tyrosine-protein kinase Fer [EC:2.7.10.2] 
K07527 FES; tyrosine-protein kinase Fes/Fps [EC:2.7.10.2] 
K20126 NOSTRIN; nostrin 
K18618 GAS7; growth arrest-specific protein 7 
     I-BAR proteins
   Rab GTPases and associated proteins
   Arf GTPases and associated proteins
   Others
 
 Endosome - Lysosome transport
 
 Protein recycling
 
 Endosome - Golgi transport
 
 Endoplasmic reticulum (ER) - Golgi transport
 
 Autophagy
 
 Others

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Last updated: April 10, 2024