Membrane Trafficking - Homo sapiens (human)

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     KO
 Exocytosis
 
 SNARE
 
 Endocytosis
   Clathrin-mediated endocytosis
   Lipid raft mediated endocytosis
   Phagocytosis
   Macropinocytosis
   Bin/Amphiphysin/Rvs (BAR) family proteins
   Rab GTPases and associated proteins
     Rab GTPases
     Rab associated proteins
       51479 ANKFY1; ankyrin repeat and FYVE domain containing 1
       9135 RABEP1; rabaptin, RAB GTPase binding effector protein 1
       79874 RABEP2; rabaptin, RAB GTPase binding effector protein 2
       27342 RABGEF1; RAB guanine nucleotide exchange factor 1
       8411 EEA1; early endosome antigen 1
       64145 RBSN; rabenosyn, RAB effector
       4952 OCRL; OCRL inositol polyphosphate-5-phosphatase
       3633 INPP5B; inositol polyphosphate-5-phosphatase B
       3635 INPP5D; inositol polyphosphate-5-phosphatase D
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5294 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
       5289 PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       30849 PIK3R4; phosphoinositide-3-kinase regulatory subunit 4
       23533 PIK3R5; phosphoinositide-3-kinase regulatory subunit 5
       146850 PIK3R6; phosphoinositide-3-kinase regulatory subunit 6
       11311 VPS45; vacuolar protein sorting 45 homolog
       26060 APPL1; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
       55198 APPL2; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
       9712 USP6NL; USP6 N-terminal like
       101060321 TBC1D3G; TBC1 domain family member 3G
       101060351 TBC1D3K; TBC1 domain family member 3K
       101060376 TBC1D3L; TBC1 domain family member 3L
       101060389 TBC1D3D; TBC1 domain family member 3D
       102723859 TBC1D3E; TBC1 domain family member 3E
       102724862 TBC1D3I; TBC1 domain family member 3I
       414059 TBC1D3B; TBC1 domain family member 3B
       414060 TBC1D3C; TBC1 domain family member 3C
       729873 TBC1D3; TBC1 domain family member 3
       729877 TBC1D3H; TBC1 domain family member 3H
       84218 TBC1D3F; TBC1 domain family member 3F
       3064 HTT; huntingtin
       474383 F8A2; coagulation factor VIII associated 2
       474384 F8A3; coagulation factor VIII associated 3
       8263 F8A1; coagulation factor VIII associated 1
       185 AGTR1; angiotensin II receptor type 1
       29800 ZDHHC1; zinc finger DHHC-type containing 1
       653082 ZDHHC11B; zinc finger DHHC-type containing 11B
       79844 ZDHHC11; zinc finger DHHC-type containing 11
       9610 RIN1; Ras and Rab interactor 1
       54453 RIN2; Ras and Rab interactor 2
       79890 RIN3; Ras and Rab interactor 3
K20129 ANKFY1; rabankyrin-5 
K12480 RABEP1; Rab GTPase-binding effector protein 1 
K20130 RABEP2; Rab GTPase-binding effector protein 2 
K20131 RABGEF1; Rab5 GDP/GTP exchange factor 
K12478 EEA1; early endosome antigen 1 
K12481 RBSN; rabenosyn-5 
K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36] 
K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36] 
K03084 SHIP1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86] 
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153] 
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153] 
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153] 
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153] 
K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137] 
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta 
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta 
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta 
K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1] 
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6 
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6 
K12479 VPS45; vacuolar protein sorting-associated protein 45 
K08733 APPL1; DCC-interacting protein 13 alpha 
K20132 APPL2; DCC-interacting protein 13 beta 
K20133 USP6NL; USP6 N-terminal-like protein 
K20134 TBC1D3; TBC1 domain family member 3 
K20134 TBC1D3; TBC1 domain family member 3 
K20134 TBC1D3; TBC1 domain family member 3 
K20134 TBC1D3; TBC1 domain family member 3 
K20134 TBC1D3; TBC1 domain family member 3 
K20134 TBC1D3; TBC1 domain family member 3 
K20134 TBC1D3; TBC1 domain family member 3 
K20134 TBC1D3; TBC1 domain family member 3 
K20134 TBC1D3; TBC1 domain family member 3 
K20134 TBC1D3; TBC1 domain family member 3 
K20134 TBC1D3; TBC1 domain family member 3 
K04533 HD; huntingtin 
K20135 F8A; factor VIII intron 22 protein 
K20135 F8A; factor VIII intron 22 protein 
K20135 F8A; factor VIII intron 22 protein 
K04166 AGTR1; angiotensin II receptor type 1 
K20027 ZDHHC1_11; palmitoyltransferase ZDHHC1/11 [EC:2.3.1.225] 
K20027 ZDHHC1_11; palmitoyltransferase ZDHHC1/11 [EC:2.3.1.225] 
K20027 ZDHHC1_11; palmitoyltransferase ZDHHC1/11 [EC:2.3.1.225] 
K17638 RIN1; Ras and Rab interactor 1 
K23687 RIN2_3; Ras and Rab interactor 2/3 
K23687 RIN2_3; Ras and Rab interactor 2/3 
   Arf GTPases and associated proteins
   Others
 
 Endosome - Lysosome transport
 
 Protein recycling
 
 Endosome - Golgi transport
 
 Endoplasmic reticulum (ER) - Golgi transport
 
 Autophagy
 
 Others

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Last updated: April 10, 2024