Membrane Trafficking - Mus musculus (house mouse)

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     KO
 Exocytosis
 
 SNARE
 
 Endocytosis
   Clathrin-mediated endocytosis
     Clathrin
     Dynamin
     AP-2 complex
     Other core components
       218503 Fcho2; FCH domain only 2
       74015 Fcho1; FCH domain only 1
       13854 Epn1; epsin 1
       13855 Epn2; epsin 2
       71889 Epn3; epsin 3
       13858 Eps15; epidermal growth factor receptor pathway substrate 15
       13859 Eps15l1; epidermal growth factor receptor pathway substrate 15-like 1
       58194 Sh3kbp1; SH3-domain kinase binding protein 1
       20616 Snap91; synaptosomal-associated protein 91
       233489 Picalm; phosphatidylinositol binding clathrin assembly protein
       16443 Itsn1; intersectin 1 (SH3 domain protein 1A)
       20403 Itsn2; intersectin 2
       218038 Amph; amphiphysin
       30948 Bin1; bridging integrator 1
       170625 Snx18; sorting nexin 18
       235406 Snx33; sorting nexin 33
       66616 Snx9; sorting nexin 9
       72685 Dnajc6; DnaJ heat shock protein family (Hsp40) member C6
       231580 Gak; cyclin G associated kinase
       15481 Hspa8; heat shock protein 8
       15482 Hspa1l; heat shock protein 1-like
       193740 Hspa1a; heat shock protein 1A
       15511 Hspa1b; heat shock protein 1B
       15512 Hspa2; heat shock protein 2
K20042 FCHO; F-BAR domain only protein 
K20042 FCHO; F-BAR domain only protein 
K12471 EPN; epsin 
K12471 EPN; epsin 
K12471 EPN; epsin 
K12472 EPS15; epidermal growth factor receptor substrate 15 
K12472 EPS15; epidermal growth factor receptor substrate 15 
K12470 SH3KBP1; SH3 domain-containing kinase-binding protein 1 
K20043 SNAP91; clathrin coat assembly protein AP180 
K20044 PICALM; phosphatidylinositol-binding clathrin assembly protein 
K20045 ITSN; intersectin 
K20045 ITSN; intersectin 
K12562 AMPH; amphiphysin 
K12562 AMPH; amphiphysin 
K17923 SNX9_18_33; sorting nexin-9/18/33 
K17923 SNX9_18_33; sorting nexin-9/18/33 
K17923 SNX9_18_33; sorting nexin-9/18/33 
K09526 DNAJC6; DnaJ homolog subfamily C member 6 
K08855 GAK; cyclin G-associated kinase [EC:2.7.11.1] 
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8 
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8 
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8 
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8 
K26598 HSPA2; heat shock 70kDa protein 2 
     Low-density lipoprotein receptor (LDLR) family proteins
     LDLR adaptor proteins
     GPCR adaptor proteins
     Receptor tyrosine kinase (RTK) adaptor proteins
     Inositol 5-phosphatases
     Kinases
     Ubiquitin E3 ligases
     Others
   Lipid raft mediated endocytosis
   Phagocytosis
   Macropinocytosis
   Bin/Amphiphysin/Rvs (BAR) family proteins
   Rab GTPases and associated proteins
   Arf GTPases and associated proteins
   Others
 
 Endosome - Lysosome transport
 
 Protein recycling
 
 Endosome - Golgi transport
 
 Endoplasmic reticulum (ER) - Golgi transport
 
 Autophagy
   Autophagosome formation proteins
   Cytoplasm to vacuolar targeting (CVT) pathway
   Mitophagy
   Pexophagy
   Aggrephagy
   Xenophagy
   Chaperone mediated autophagy (CMA)
     Selective cargos
     Cargo receptors
     Chaperones
       15481 Hspa8; heat shock protein 8
       15482 Hspa1l; heat shock protein 1-like
       193740 Hspa1a; heat shock protein 1A
       15511 Hspa1b; heat shock protein 1B
       15512 Hspa2; heat shock protein 2
       15519 Hsp90aa1; heat shock protein 90, alpha (cytosolic), class A member 1
       15516 Hsp90ab1; heat shock protein 90 alpha (cytosolic), class B member 1
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8 
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8 
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8 
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8 
K26598 HSPA2; heat shock 70kDa protein 2 
K04079 HSP90A; molecular chaperone HtpG 
K04079 HSP90A; molecular chaperone HtpG 
     Co-chaperones
     Other CMA associated proteins
   Other autophagy associated proteins
 
 Others

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Last updated: April 10, 2024