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 1. Oxidoreductases
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2. Transferases
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3. Hydrolases
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4. Lyases
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 5. Isomerases
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5.1 Racemases and epimerases
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5.2 cis-trans-Isomerases
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5.3 Intramolecular oxidoreductases
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5.4 Intramolecular transferases
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5.5 Intramolecular lyases
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5.6 Isomerases altering macromolecular conformation
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5.6.1 Enzymes altering polypeptide conformation or assembly
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5.6.2 Enzymes altering nucleic acid conformation
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5.6.2.1 DNA topoisomerase
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5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
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5.6.2.3 DNA 5'-3' helicase
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 SPAC1B2.05 mcm5; MCM complex subunit Mcm5
SPBC25D12.03c mcm7; MCM complex subunit Mcm7
SPCC16A11.17 mcm4; MCM complex subunit Mcm4/Cdc21
SPBC4.04c mcm2; MCM complex subunit Mcm2
SPCC1682.02c mcm3; MCM complex subunit Mcm3
SPBC211.04c mcm6; MCM complex subunit Mcm6
SPBC16D10.04c dna2; DNA replication endonuclease-helicase Dna2
SPAC1D4.12 rad15; transcription factor TFIIH complex subunit Rad15
SPBC83.08 rvb2; AAA family ATPase Rvb2
SPAC16C9.06c upf1; ATP-dependent RNA helicase Upf1
SPBC887.14c pfh1; DNA repair and recombination protein
SPCC737.07c putative DNA polymerase alpha-associated DNA helicase A
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K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
K02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]
K02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]
K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
K02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
K19783 HCS1; DNA polymerase alpha-associated DNA helicase A [EC:5.6.2.3]
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5.6.2.4 DNA 3'-5' helicase
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5.6.2.5 RNA 5'-3' helicase
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5.6.2.6 RNA 3'-5' helicase
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5.6.2.7 DEAD-box RNA helicase
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5.99 Other isomerases
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6. Ligases
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7. Translocases
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Enzymes - Schizosaccharomyces pombe (fission yeast)