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ENTRY	nt06030
Name	Methionine metabolism
Category	Pathway view; Amino acid metabolism
Pathway	hsa00270 Cysteine and methionine metabolism hsa00230 Purine metabolism hsa00670 One carbon pool by folate
Module	hsa_M00035 Methionine degradation hsa_M00338 Cysteine biosynthesis, homocysteine + serine => cysteine
Disease	H00184 Hypermethioninemia
Display	drug-target relation   disease type

N01607    Met − MAT ⇉ (GNMT,DNMT) ⇉ AHCY → Hcy+Adenosine     MAT I/III deficiency     MAT1A*     GNMT deficiency         GNMT*     SAHH deficiency             AHCY* N01627    Adenosine − ADK → AMP     ADK deficiency     ADK*   N01628    Ser+Hcy − CBS ⇉ CTH → Cys     Homocystinuria     CBS*     Cystathioninuria         CTH*   N01629    THF − SHMT ⇉ MTHFR → 5-MTHF     Homocystinuria         MTHFR* N01630    Hcy+5-MTHF − (BHMT1/2,MTR) → Met+THF     Homocystinuria     MTR*

		Disease name	Disease category
MAT I/III deficiency	H00184	Hypermethioninemia	Inherited metabolic disorder
GNMT deficiency	H00184	Hypermethioninemia	Inherited metabolic disorder
SAHH deficiency	H00184	Hypermethioninemia	Inherited metabolic disorder
ADK deficiency	H00184	Hypermethioninemia	Inherited metabolic disorder
Homocystinuria	H00183	Homocystinuria	Inherited metabolic disorder
Cystathioninuria	H00182	Cystathioninuria	Inherited metabolic disorder