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TARA_ERS488737_N000113_47 / Result of BLASTP

browse BLASTP result of all genes from this scaffold

subject	subject definition	idt	len	mis	gap	q.start	q.end	s.start	s.end	evalue	bit.score
subject	subject definition	idt	len	mis	gap	q.start	q.end	s.start	s.end	evalue	bit.score
rs:WP_021393615	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.14	697	417	17	1	673	1	672	3e-104	345
rs:WP_002584963	MULTISPECIES: DNA topoisomerase III [Clostridiales].	32.95	695	421	16	1	673	1	672	2e-103	342
rs:WP_026808919	DNA topoisomerase III [Arenibacter latericius].	32.31	718	415	21	1	677	1	688	2e-102	342
rs:WP_045643222	DNA topoisomerase III [Peptococcaceae bacterium BRH_c8a].	32.76	696	431	18	2	675	6	686	1e-101	340
rs:WP_021989105	DNA topoisomerase III [Odoribacter sp. CAG:788].	31.36	708	438	19	1	676	1	692	4e-101	337
rs:WP_040647948	hypothetical protein [Ruminococcus callidus].	32.86	703	415	20	1	673	1	676	7e-101	336
rs:WP_007709571	hypothetical protein [[Clostridium] asparagiforme].	32.71	700	416	18	1	673	1	672	9e-101	335
rs:WP_046495771	hypothetical protein [Syntrophomonas zehnderi].	33.76	699	416	20	3	676	4	680	1e-100	335
tr:D5HIG2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	32.10	701	412	18	1	673	1	665	3e-100	335
rs:WP_026508071	DNA topoisomerase III [Butyrivibrio sp. MC2013].	32.18	696	419	18	1	673	1	666	4e-100	334
rs:WP_002594223	DNA topoisomerase III [[Clostridium] clostridioforme].	33.05	699	412	19	1	673	1	669	8e-100	333
rs:WP_026475568	DNA topoisomerase III [Alkaliflexus imshenetskii].	32.72	703	430	21	1	676	1	687	1e-99	335
tr:H1DJY9_9PORP	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.31	709	444	17	1	680	1	695	1e-99	333
rs:WP_045644513	DNA topoisomerase III [Peptococcaceae bacterium BRH_c4b].	32.90	696	430	16	3	673	4	687	2e-99	332
rs:WP_016147854	DNA topoisomerase III [Butyricicoccus pullicaecorum].	31.71	697	424	18	1	673	1	669	3e-99	331
rs:WP_009906246	DNA topoisomerase III [Peptoclostridium difficile].	33.10	701	416	18	1	673	1	676	3e-99	331
rs:WP_041726130	hypothetical protein [Caldisericum exile].	32.51	689	423	16	3	669	5	673	4e-99	334
tr:I0GKW5_CALEA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.51	689	423	16	3	669	4	672	5e-99	334
rs:WP_034104804	DNA topoisomerase III [Desulfotomaculum sp. BICA1-6].	32.95	698	426	18	2	675	6	685	6e-99	333
rs:WP_017872293	hypothetical protein [Candidatus Caldatribacterium saccharofermentans].	32.11	710	428	18	2	680	4	690	7e-99	331
rs:WP_015245972	DNA topoisomerase III [Singulisphaera acidiphila].	31.46	658	395	18	1	635	1	625	1e-98	333
rs:WP_044638498	DNA topoisomerase III [Siansivirga zeaxanthinifaciens].	31.82	704	441	17	1	680	1	689	2e-98	332
rs:WP_018086956	hypothetical protein [Desulfurispora thermophila].	30.29	700	452	14	3	680	5	690	2e-98	330
rs:WP_002610336	MULTISPECIES: DNA topoisomerase III [Firmicutes].	32.95	701	417	18	1	673	1	676	2e-98	329
rs:WP_044904689	DNA topoisomerase III [[Clostridium] innocuum].	32.78	668	409	15	28	673	5	654	2e-98	328
rs:WP_022048204	DNA topoisomerase III [Odoribacter laneus CAG:561].	31.31	709	444	17	1	680	1	695	2e-98	329
tr:A0A099I8C9_CLOIN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	32.78	668	409	15	28	673	11	660	3e-98	328
tr:D6DKQ5_CLOSC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.00	697	418	18	1	673	1	672	4e-98	328
rs:WP_006774454	DNA topoisomerase III [[Clostridium] hathewayi].	33.00	697	418	18	1	673	1	672	4e-98	328
rs:WP_040612006	DNA topoisomerase III, partial [Odoribacter laneus].	31.70	675	419	16	1	647	1	661	5e-98	327
rs:WP_006520575	DNA topoisomerase III [Desulfotomaculum gibsoniae].	32.52	701	435	17	2	679	3	688	5e-98	331
rs:WP_026815025	DNA topoisomerase III [Arenibacter certesii].	31.24	717	424	20	1	677	1	688	7e-98	330
rs:WP_045642169	DNA topoisomerase III [Peptococcaceae bacterium BRH_c8a].	33.09	698	425	18	2	675	6	685	1e-97	330
rs:WP_035234409	hypothetical protein, partial [Desulfobulbus sp. Tol-SR].	30.67	675	417	16	1	652	1	647	1e-97	327
rs:WP_008979754	DNA topoisomerase III [Peptoclostridium difficile].	33.00	697	418	17	1	673	1	672	1e-97	327
rs:WP_034686218	DNA topoisomerase III [Chryseobacterium piperi].	33.24	710	426	17	1	675	1	697	1e-97	327
rs:WP_034630178	DNA topoisomerase III [Desulfotomaculum alcoholivorax].	33.85	712	422	20	3	682	4	698	2e-97	327
rs:WP_024858731	DNA topoisomerase III [Ruminococcus albus].	32.83	661	409	16	3	655	4	637	2e-97	326
rs:WP_006745733	DNA topoisomerase III [Bacteroides coprosuis].	32.09	645	400	15	1	629	1	623	2e-97	325
rs:WP_044302118	DNA topoisomerase [Rhodopirellula sallentina].	32.61	693	393	21	1	652	1	660	3e-97	330
rs:WP_021434670	DNA topoisomerase III [Peptoclostridium difficile].	33.05	711	423	18	1	683	1	686	3e-97	326
rs:WP_007651964	DNA topoisomerase III [Pontibacter sp. BAB1700].	31.22	724	439	20	1	680	1	709	4e-97	329
rs:WP_036074259	DNA topoisomerase III [Listeria aquatica].	34.98	649	370	21	3	627	5	625	4e-97	327
rs:WP_042519962	MULTISPECIES: DNA topoisomerase III [Prevotella].	32.45	681	397	15	1	630	1	669	5e-97	325
rs:WP_044074329	DNA topoisomerase III [Prevotella sp. P5-60].	32.75	681	395	16	1	630	1	669	5e-97	325
rs:WP_021426980	DNA topoisomerase III [Peptoclostridium difficile].	32.81	701	418	19	1	673	1	676	6e-97	325
rs:WP_044254218	DNA topoisomerase [Rhodopirellula sp. SWK7].	31.84	691	401	19	1	652	1	660	7e-97	328
rs:WP_003431259	DNA topoisomerase [Peptoclostridium difficile].	32.86	697	419	17	1	673	1	672	7e-97	325
rs:WP_021422174	DNA topoisomerase III [Peptoclostridium difficile].	32.67	701	419	18	1	673	1	676	8e-97	325
rs:WP_022317548	MULTISPECIES: DNA topoisomerase III [Prevotella].	32.75	681	395	16	1	630	1	669	1e-96	324
rs:WP_046402305	DNA topoisomerase III [Odoribacter sp. UNK.MGS-12].	29.90	719	443	19	1	679	1	698	1e-96	325
rs:WP_004607961	DNA topoisomerase III [[Clostridium] scindens].	33.24	698	418	19	1	673	1	675	1e-96	325
rs:WP_021419783	DNA topoisomerase III [Peptoclostridium difficile].	32.52	701	420	19	1	673	1	676	1e-96	325
rs:WP_009905259	DNA topoisomerase III [Peptoclostridium difficile].	32.67	704	415	20	1	673	1	676	2e-96	324
tr:M5U4I0_9PLAN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.47	693	394	21	1	652	10	669	2e-96	328
rs:WP_013613151	DNA topoisomerase III [Odoribacter splanchnicus].	29.97	724	440	20	1	679	1	702	2e-96	324
rs:WP_005943447	DNA topoisomerase III [Faecalibacterium prausnitzii].	31.80	695	425	17	1	671	3	672	2e-96	324
rs:WP_016562551	DNA topoisomerase III [Bacteroides sp. CAG:927].	31.32	696	413	17	1	650	1	677	2e-96	323
rs:WP_004604812	DNA topoisomerase III [[Clostridium] scindens].	32.86	700	419	17	1	673	1	676	2e-96	324
rs:WP_022160958	DNA topoisomerase III [Odoribacter splanchnicus CAG:14].	29.97	724	440	20	1	679	1	702	3e-96	324
rs:WP_003542029	DNA topoisomerase III [Desulfotomaculum nigrificans].	32.30	709	428	20	3	680	4	691	3e-96	326
rs:WP_033119050	DNA topoisomerase III [Intestinimonas butyriciproducens].	31.94	695	423	18	2	671	5	674	3e-96	323
rs:WP_046405598	DNA topoisomerase III [Odoribacter sp. N15.MGS-14].	30.11	724	439	22	1	679	1	702	3e-96	324
rs:WP_044079817	DNA topoisomerase III [Prevotella sp. P4-65].	32.60	681	396	16	1	630	1	669	3e-96	323
tr:M5T3X4_9PLAN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.54	688	407	17	1	652	2	661	3e-96	327
rs:WP_017890391	hypothetical protein [Candidatus Caldatribacteirum californiense].	31.59	709	433	18	2	680	4	690	4e-96	323
rs:WP_021361815	DNA topoisomerase III [Peptoclostridium difficile].	32.16	709	432	19	1	683	1	686	6e-96	323
rs:WP_041502811	MULTISPECIES: DNA topoisomerase III [unclassified Porphyromonadaceae].	30.14	710	451	22	1	683	1	692	7e-96	323
rs:WP_042398858	hypothetical protein [Clostridium sp. JCC].	32.96	710	420	19	1	680	1	684	7e-96	322
rs:WP_018478536	DNA topoisomerase III [Pontibacter roseus].	29.92	732	455	16	1	687	1	719	8e-96	325
rs:WP_011861108	DNA topoisomerase III [Peptoclostridium difficile].	32.16	709	432	19	1	683	1	686	9e-96	322
rs:WP_034713734	DNA topoisomerase III [Chryseobacterium soli].	33.53	686	404	17	1	650	1	670	1e-95	322
rs:WP_024833195	DNA topoisomerase III [[Clostridium] josui].	33.38	656	383	20	3	627	5	637	1e-95	323
rs:WP_024725165	hypothetical protein [Clostridiales bacterium VE202-03].	31.87	706	425	18	1	673	1	683	1e-95	322
rs:WP_003508269	DNA topoisomerase [[Clostridium] symbiosum].	32.57	697	421	17	1	673	1	672	1e-95	322
rs:WP_022617840	DNA topoisomerase III; Tn1549-like, CTn4-Orf15 [Peptoclostridium difficile].	32.02	709	433	19	1	683	1	686	1e-95	322
rs:WP_007037046	DNA topoisomerase III [[Clostridium] bolteae].	33.09	698	419	19	1	673	1	675	2e-95	322
rs:WP_028913321	DNA topoisomerase III [Prevotella sp. MA2016].	32.63	711	382	23	1	630	1	695	2e-95	322
rs:WP_002584840	MULTISPECIES: DNA topoisomerase III [Lachnoclostridium].	31.89	693	426	16	1	673	1	667	2e-95	322
tr:R9II52_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.19	696	421	18	1	673	1	675	2e-95	321
rs:WP_036915603	DNA topoisomerase III, partial [Prevotella sp. P6B4].	34.41	622	362	17	1	590	1	608	2e-95	319
rs:WP_002596359	DNA topoisomerase III [[Clostridium] clostridioforme].	30.48	689	439	17	1	673	1	665	2e-95	321
gp:CP009679_388	DNA topoisomerase 3 [Bacillus methylotrophicus]	34.60	659	378	22	3	631	13	648	3e-95	322
rs:WP_025577806	DNA topoisomerase III [Blautia wexlerae].	32.86	697	420	19	2	673	4	677	3e-95	321
rs:WP_025579750	DNA topoisomerase III [Blautia wexlerae].	32.81	701	418	19	1	673	1	676	3e-95	321
rs:WP_014081130	DNA topoisomerase III [Roseburia hominis].	30.48	689	439	17	1	673	1	665	3e-95	321
rs:WP_038461743	MULTISPECIES: DNA topoisomerase III [Bacillus].	34.60	659	378	22	3	631	5	640	3e-95	322
rs:WP_018963384	hypothetical protein [Coprothermobacter platensis].	33.33	693	408	21	3	673	4	664	5e-95	320
rs:WP_045372352	DNA topoisomerase III [Jejuia pallidilutea].	31.75	715	427	22	1	680	1	689	5e-95	322
rs:WP_005935077	DNA topoisomerase III [Faecalibacterium prausnitzii].	31.02	706	429	16	2	671	4	687	5e-95	321
rs:WP_033150038	DNA topoisomerase III [Prevotella sp. RM4].	32.44	709	392	21	1	641	1	690	5e-95	320
rs:WP_020157765	DNA topoisomerase [Methylobacter marinus].	33.08	671	403	16	1	652	1	644	5e-95	322
rs:WP_024980194	DNA topoisomerase III [Flavobacterium succinicans].	32.09	723	419	25	1	680	1	694	5e-95	322
rs:WP_027158454	DNA topoisomerase [Methylobacter luteus].	32.78	668	406	14	1	652	1	641	6e-95	322
rs:WP_006892423	DNA topoisomerase [Methylobacter tundripaludum].	33.28	682	407	19	1	655	1	661	7e-95	322
rs:WP_027380549	DNA topoisomerase III [Chryseobacterium daeguense].	33.38	716	424	21	1	678	1	701	7e-95	320
rs:WP_033148685	DNA topoisomerase III, partial [Prevotella sp. P6B1].	34.24	622	363	17	1	590	1	608	8e-95	318
rs:WP_034229460	DNA topoisomerase III [Lachnospiraceae bacterium 3-1].	33.05	696	422	18	1	673	3	677	8e-95	320
rs:WP_020816211	DNA topoisomerase III [[Clostridium] papyrosolvens].	32.77	656	387	20	3	627	5	637	8e-95	320
rs:WP_020492504	DNA topoisomerase III [Dehalobacter sp. FTH1].	33.38	650	386	17	3	626	4	632	1e-94	319
rs:WP_027586242	DNA topoisomerase III [Prolixibacter bellariivorans].	32.11	710	421	21	1	673	1	686	1e-94	322
rs:WP_006859375	DNA topoisomerase III [Roseburia intestinalis].	31.03	696	429	17	1	673	1	668	1e-94	320
rs:WP_004070246	DNA topoisomerase III [Clostridium sp. ASF502].	31.60	693	428	17	1	673	1	667	1e-94	320
rs:WP_010136018	DNA topoisomerase III [Flavobacteriaceae bacterium S85].	32.04	721	416	23	1	677	1	691	1e-94	321
rs:WP_002585520	DNA topoisomerase III [[Clostridium] clostridioforme].	31.31	693	428	19	1	671	1	667	1e-94	319
rs:WP_002569178	MULTISPECIES: DNA topoisomerase III [Firmicutes].	32.71	697	421	19	2	673	4	677	1e-94	319
rs:WP_026969602	DNA topoisomerase III [Algoriphagus terrigena].	31.46	712	430	20	1	677	1	689	2e-94	321
rs:WP_039367564	DNA topoisomerase III [Chryseobacterium taiwanense].	33.38	716	420	20	1	676	1	699	2e-94	319
gp:HE963029_27	DNA topoisomerase (pseudogene) [Enterococcus faecium]	31.90	696	422	18	2	671	4	673	2e-94	319
rs:WP_022621591	DNA topoisomerase III; Tn1549-like, CTn4-Orf15 [Peptoclostridium difficile].	32.52	701	420	19	1	673	1	676	2e-94	319
rs:WP_005927750	DNA topoisomerase III [Faecalibacterium prausnitzii].	31.98	691	427	17	1	671	3	670	2e-94	319
rs:WP_013578458	DNA topoisomerase III [Granulicella tundricola].	32.49	714	435	22	1	678	1	703	2e-94	319
rs:WP_034757415	DNA topoisomerase III [Chryseobacterium sp. OV259].	32.21	714	428	20	1	675	1	697	2e-94	319
rs:WP_039062795	DNA topoisomerase III [Bacillus amyloliquefaciens].	34.45	659	379	22	3	631	5	640	2e-94	320
rs:WP_019387032	DNA topoisomerase III [Arenitalea lutea].	30.95	714	434	19	1	680	1	689	2e-94	320
rs:WP_021388553	DNA topoisomerase III [Peptoclostridium difficile].	32.10	701	423	19	1	673	1	676	2e-94	318
rs:WP_045147099	DNA topoisomerase III [Peptoclostridium difficile].	32.61	696	425	19	1	673	3	677	2e-94	318
rs:WP_029199505	DNA topoisomerase III [Oribacterium sp. NK2B42].	31.85	697	414	20	2	673	4	664	2e-94	318
rs:WP_018462451	DNA topoisomerase III [Prevotella paludivivens].	32.56	694	391	18	1	629	1	682	2e-94	318
rs:WP_027201773	DNA topoisomerase III [Butyricimonas virosa].	29.95	728	438	23	1	683	1	701	3e-94	318
rs:WP_010527810	DNA topoisomerase III [Thermophagus xiamenensis].	32.06	705	437	18	1	676	1	692	3e-94	321
rs:WP_008978034	DNA topoisomerase III [Erysipelotrichaceae bacterium 5_2_54FAA].	32.71	697	421	19	2	673	4	677	3e-94	318
rs:WP_002585092	DNA topoisomerase III [[Clostridium] clostridioforme].	32.62	699	421	20	1	673	3	677	3e-94	318
rs:WP_029296993	DNA topoisomerase III [Chryseobacterium hispalense].	32.73	715	426	20	1	677	1	698	3e-94	318
rs:WP_027147611	DNA topoisomerase [Methylobacter tundripaludum].	32.61	696	406	17	1	655	1	674	3e-94	321
rs:WP_036248694	DNA topoisomerase [Methylobacter sp. BBA5.1].	32.94	671	404	16	1	652	1	644	3e-94	320
rs:WP_002417647	DNA topoisomerase III [Enterococcus faecalis].	31.90	696	422	18	2	671	4	673	3e-94	318
rs:WP_021361579	DNA topoisomerase III [Peptoclostridium difficile].	32.10	701	423	19	1	673	1	676	4e-94	318
rs:WP_036156598	DNA topoisomerase III [Maribacter forsetii].	32.24	704	432	20	1	676	1	687	4e-94	320
rs:WP_016289907	DNA topoisomerase III [Lachnospiraceae bacterium 28-4].	32.42	697	423	19	2	673	4	677	4e-94	318
rs:WP_027136773	DNA topoisomerase III [Gaetbulibacter saemankumensis].	32.03	715	417	21	1	676	1	685	4e-94	320
rs:WP_016222100	DNA topoisomerase III [Dorea sp. 5-2].	31.17	693	425	17	3	673	4	666	5e-94	318
rs:WP_040994040	DNA topoisomerase III [Chryseobacterium oranimense].	33.01	715	417	20	1	673	1	695	5e-94	318
rs:WP_009447128	DNA topoisomerase III [Lachnospiraceae bacterium oral taxon 082].	32.61	696	425	18	1	673	3	677	5e-94	318
rs:WP_014314712	DNA topoisomerase III [Clostridium sp. BNL1100].	32.77	656	387	20	3	627	5	637	5e-94	318
rs:WP_002317284	MULTISPECIES: DNA topoisomerase III [Bacteria].	31.90	696	422	18	2	671	4	673	6e-94	317
rs:WP_044632471	DNA topoisomerase III [Tamlana sedimentorum].	31.89	718	415	25	1	676	1	686	6e-94	319
rs:WP_033143528	DNA topoisomerase III [Blautia producta].	30.38	711	444	18	1	683	1	688	6e-94	318
rs:WP_028908338	DNA topoisomerase III [Prevotella ruminicola].	32.09	723	390	22	1	641	1	704	6e-94	318
rs:WP_013063148	DNA topoisomerase III [Prevotella ruminicola].	32.44	712	383	22	1	630	1	696	7e-94	317
rs:WP_021948190	DNA topoisomerase III [Prevotella sp. CAG:1124].	31.97	685	398	16	1	629	1	673	7e-94	317
rs:WP_036297314	DNA topoisomerase [Methylobacter whittenburyi].	33.08	671	403	16	1	652	1	644	8e-94	319
rs:WP_007860201	hypothetical protein [[Clostridium] citroniae].	32.86	697	419	17	1	673	1	672	9e-94	317
rs:WP_015010818	DNA topoisomerase III [Amphibacillus xylanus].	32.45	644	396	17	3	627	5	628	9e-94	318
rs:WP_008271599	DNA topoisomerase III [Flavobacteriales bacterium ALC-1].	32.82	719	409	23	1	676	1	688	9e-94	318
rs:WP_037298423	DNA topoisomerase III [Ruminococcus flavefaciens].	32.28	663	408	17	3	654	4	636	9e-94	316
rs:WP_021749501	MULTISPECIES: DNA topoisomerase [Oscillibacter].	32.42	697	422	17	1	673	1	672	9e-94	317
rs:WP_044942468	DNA topoisomerase III [Flavonifractor plautii].	32.57	697	421	17	1	673	1	672	1e-93	317
rs:WP_007840343	MULTISPECIES: DNA topoisomerase III [Chryseobacterium].	33.01	712	421	20	1	673	1	695	1e-93	317
rs:WP_002573997	DNA topoisomerase III [[Clostridium] bolteae].	30.94	695	433	18	1	671	3	674	1e-93	317
rs:WP_034604312	MULTISPECIES: DNA topoisomerase III, partial [Desulfovibrio].	31.00	742	423	24	3	681	5	720	1e-93	317
tr:C6LDA7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.43	713	441	20	1	683	6	693	1e-93	317
rs:WP_014224886	DNA topoisomerase III [Tannerella forsythia].	30.80	711	413	20	1	652	1	691	1e-93	317
rs:WP_013823470	DNA topoisomerase III [Desulfotomaculum kuznetsovii].	31.18	712	437	18	2	680	3	694	1e-93	319
rs:WP_007884149	DNA topoisomerase III [Roseburia inulinivorans].	32.76	696	420	19	3	673	1	673	1e-93	317
rs:WP_019225406	DNA topoisomerase III [Dehalobacter sp. E1].	33.08	650	388	17	3	626	4	632	1e-93	317
rs:WP_044925917	DNA topoisomerase III [[Ruminococcus] obeum].	32.58	709	418	22	1	679	1	679	1e-93	317
rs:WP_025205685	DNA topoisomerase III [Dehalobacter restrictus].	33.08	650	388	17	3	626	4	632	1e-93	316
rs:WP_040782654	DNA topoisomerase III [Marvinbryantia formatexigens].	30.43	713	441	20	1	683	1	688	2e-93	317
rs:WP_023056591	MULTISPECIES: DNA topoisomerase III [Prevotella].	33.12	622	363	16	1	590	1	601	2e-93	314
rs:WP_028910324	DNA topoisomerase III [Prevotella sp. AGR2160].	32.50	683	396	21	1	630	1	671	2e-93	316
rs:WP_020561698	hypothetical protein [Methylosarcina fibrata].	31.73	665	417	15	1	652	1	641	2e-93	318
rs:WP_027386103	DNA topoisomerase III [Chryseobacterium gregarium].	32.96	713	428	20	1	677	1	699	2e-93	316
rs:WP_022252283	DNA topoisomerase III [Prevotella sp. CAG:386].	31.82	704	393	20	1	629	1	692	2e-93	316
rs:WP_007884408	DNA topoisomerase III [Roseburia inulinivorans].	32.18	696	424	16	1	671	1	673	2e-93	316
gpu:AP013045_655	DNA topoisomerase [Tannerella forsythia KS16]	30.94	711	412	20	1	652	1	691	3e-93	316
rs:WP_036120904	DNA topoisomerase III [Mangrovimonas yunxiaonensis].	31.75	715	423	24	1	678	1	687	3e-93	317
rs:WP_002370803	DNA topoisomerase III [Enterococcus faecium].	31.75	696	423	18	2	671	4	673	3e-93	315
rs:WP_026954375	DNA topoisomerase III [Algoriphagus vanfongensis].	31.64	708	427	22	1	675	1	684	4e-93	317
rs:WP_009433703	DNA topoisomerase III [Porphyromonas sp. oral taxon 279].	32.53	661	405	19	1	630	1	651	4e-93	315
rs:WP_039438134	DNA topoisomerase III [Porphyromonas gulae].	30.03	686	437	16	1	655	1	674	5e-93	315
rs:WP_024733189	DNA topoisomerase III [Clostridiales bacterium VE202-14].	32.57	697	418	18	1	671	1	671	5e-93	315
rs:WP_002590573	MULTISPECIES: DNA topoisomerase III [Lachnospiraceae].	33.00	700	413	21	1	671	3	675	5e-93	315
rs:WP_004350923	DNA topoisomerase III [Prevotella buccalis].	33.12	622	363	16	1	590	1	601	5e-93	313
rs:WP_016284650	DNA topoisomerase III [Lachnospiraceae bacterium A4].	31.98	691	425	17	1	669	1	668	5e-93	315
rs:WP_032509776	DNA topoisomerase III [Peptoclostridium difficile].	32.38	701	421	19	1	673	1	676	6e-93	315
rs:WP_046826025	DNA topoisomerase III [Tannerella forsythia].	30.80	711	413	20	1	652	1	691	6e-93	315
rs:WP_010662622	DNA topoisomerase III [Marinilabilia salmonicolor].	32.21	711	431	20	1	676	1	695	7e-93	317
rs:WP_002566666	DNA topoisomerase III [[Clostridium] bolteae].	31.51	695	429	18	1	671	3	674	7e-93	315
rs:WP_033883715	DNA topoisomerase III [Bacillus subtilis].	34.09	657	384	20	3	631	5	640	7e-93	315
rs:WP_027471632	DNA topoisomerase III [Saccharicrinis fermentans].	32.21	714	420	22	1	676	1	688	8e-93	317
tr:D4LTS8_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.45	716	437	19	1	683	1	688	9e-93	315
rs:WP_036928229	DNA topoisomerase III [Prevotella timonensis].	33.06	614	374	14	1	590	1	601	9e-93	312
rs:WP_041339607	DNA topoisomerase III [Bacillus subtilis].	34.45	659	379	21	3	631	5	640	9e-93	315
rs:WP_018339522	DNA topoisomerase III [Butyricimonas synergistica].	30.54	727	435	25	1	683	1	701	9e-93	315
rs:WP_035639024	DNA topoisomerase III [Flavobacterium sp. EM1308].	31.92	730	406	26	1	680	1	689	1e-92	316
rs:WP_035290026	DNA topoisomerase III [Clostridium sp. KNHs214].	32.33	696	423	16	1	671	1	673	1e-92	314
rs:WP_035070160	DNA topoisomerase III [Anditalea andensis].	30.69	707	446	17	1	678	1	692	1e-92	314
rs:WP_036872645	DNA topoisomerase III [Prevotella buccalis].	32.96	622	364	16	1	590	1	601	1e-92	311
rs:WP_003234388	DNA topoisomerase III [Bacillus subtilis].	34.40	657	382	20	3	631	5	640	1e-92	315
rs:WP_015042714	MULTISPECIES: DNA topoisomerase III [Dehalobacter].	33.08	650	388	17	3	626	4	632	2e-92	313
rs:WP_014475847	DNA topoisomerase III [Bacillus subtilis].	34.40	657	382	20	3	631	5	640	2e-92	315
rs:WP_018112824	DNA topoisomerase III [Peptoclostridium difficile].	32.38	701	421	19	1	673	1	676	2e-92	313
rs:WP_039075817	DNA topoisomerase III [Bacillus sp. MSP13].	35.39	664	366	25	3	631	5	640	2e-92	314
rs:WP_002595170	DNA topoisomerase III [[Clostridium] clostridioforme].	32.48	702	418	21	1	673	3	677	2e-92	313
rs:WP_045640846	DNA topoisomerase III [Flavobacteriales bacterium BRH_c54].	31.49	705	431	22	1	676	1	682	2e-92	315
rs:WP_039446752	DNA topoisomerase III [Porphyromonas gulae].	30.17	686	436	16	1	655	1	674	2e-92	313
rs:WP_018965808	DNA topoisomerase III [Porphyromonas gulae].	30.03	686	437	16	1	655	1	674	2e-92	313
rs:WP_008125946	DNA topoisomerase III [Prevotella timonensis].	33.06	614	374	14	1	590	1	601	2e-92	311
rs:WP_008634317	DNA topoisomerase III [Bizionia argentinensis].	31.29	719	420	23	1	676	1	688	2e-92	315
rs:WP_036084712	DNA topoisomerase III [Listeria booriae].	34.11	642	382	17	3	627	5	622	2e-92	313
rs:WP_023226745	DNA topoisomerase III [Salmonella enterica].	30.41	638	408	13	1	615	1	625	2e-92	312
tr:F2Q883_SALBN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.41	638	408	13	1	615	1	625	3e-92	312
rs:WP_031444327	DNA topoisomerase III [Arenibacter algicola].	31.04	712	432	20	1	677	1	688	3e-92	315
rs:WP_005922872	DNA topoisomerase III [Faecalibacterium prausnitzii].	31.11	691	433	16	1	671	3	670	3e-92	313
rs:WP_044169014	DNA topoisomerase III [Porphyromonas catoniae].	31.96	657	399	18	1	625	1	641	3e-92	312
rs:WP_036100249	DNA topoisomerase III [Listeria riparia].	33.96	642	383	17	3	627	5	622	3e-92	313
rs:WP_006060481	DNA topoisomerase III [Holdemania filiformis].	30.75	696	431	17	2	671	4	674	4e-92	313
rs:WP_012544366	DNA topoisomerase III [Coprothermobacter proteolyticus].	32.12	688	424	19	3	673	4	665	4e-92	312
rs:WP_001241572	DNA topoisomerase III [Salmonella enterica].	30.41	638	408	13	1	615	1	625	4e-92	312
rs:WP_005469461	DNA topoisomerase III [Porphyromonas catoniae].	32.02	659	396	21	1	625	1	641	4e-92	312
rs:WP_039439757	DNA topoisomerase III [Porphyromonas gulae].	30.03	686	437	16	1	655	1	674	4e-92	312
rs:WP_044115552	DNA topoisomerase III [Porphyromonas sp. KLE 1280].	32.28	663	406	19	1	630	1	653	4e-92	312
rs:WP_029268835	DNA topoisomerase III [Flavobacterium sp. KJJ].	31.40	723	419	25	1	680	1	689	5e-92	314
rs:WP_024799102	DNA topoisomerase III [Salmonella enterica].	30.69	642	401	15	1	615	1	625	5e-92	311
rs:WP_024479295	DNA topoisomerase III [Cellulophaga baltica].	31.66	717	427	20	1	680	1	691	5e-92	314
rs:WP_025073101	DNA topoisomerase III [Prevotella timonensis].	33.06	614	374	14	1	590	1	601	5e-92	310
rs:WP_034667368	DNA topoisomerase III [Cellulophaga sp. E6(2014)].	31.52	717	428	19	1	680	1	691	5e-92	314
rs:WP_034976722	DNA topoisomerase III [Epilithonimonas lactis].	33.19	684	400	22	1	647	1	664	6e-92	312
rs:WP_028889542	DNA topoisomerase III [Tenacibaculum ovolyticum].	32.40	716	414	23	1	676	1	686	6e-92	314
rs:WP_021661456	DNA topoisomerase [Clostridium sp. ATCC 29733].	31.21	708	436	20	1	683	1	682	6e-92	312
rs:WP_023135508	DNA topoisomerase III [Salmonella enterica].	31.45	636	400	15	1	613	1	623	6e-92	311
rs:WP_046200217	DNA topoisomerase III [Porphyromonas gulae].	30.52	688	430	19	1	655	1	673	6e-92	311
rs:WP_028509289	hypothetical protein [Ruminococcus sp. NK3A76].	32.01	706	417	20	1	678	1	671	6e-92	312
rs:WP_040281935	DNA topoisomerase III [Psychroserpens damuponensis].	32.64	723	413	26	1	680	1	692	6e-92	314
rs:WP_044013192	DNA topoisomerase III [Hymenobacter sp. APR13].	28.19	759	457	19	1	684	1	746	6e-92	316
rs:WP_016286623	DNA topoisomerase III [Lachnospiraceae bacterium 3-1].	31.52	698	423	18	1	671	1	670	6e-92	312
rs:WP_034965253	DNA topoisomerase III [Epilithonimonas sp. FH1].	33.19	684	400	22	1	647	1	664	6e-92	312
rs:WP_013551991	DNA topoisomerase III [Cellulophaga algicola].	32.49	711	422	24	1	676	1	688	7e-92	314
rs:WP_040084142	DNA topoisomerase 3 [Bacillus sp. A053].	34.09	657	384	20	3	631	5	640	7e-92	313
rs:WP_026981915	DNA topoisomerase III [Flavobacterium sp. URHB0058].	31.85	719	421	25	1	680	1	689	7e-92	314
rs:WP_017697341	DNA topoisomerase III [Bacillus subtilis].	34.29	659	380	21	3	631	5	640	7e-92	313
rs:WP_034043867	DNA topoisomerase III [Flaviramulus ichthyoenteri].	31.79	714	428	21	1	680	1	689	7e-92	313
rs:WP_015715259	DNA topoisomerase III [Bacillus subtilis].	34.25	657	383	20	3	631	5	640	7e-92	313
rs:WP_039111128	DNA topoisomerase III [Flavobacterium sp. KMS].	31.40	726	415	25	1	680	1	689	8e-92	313
rs:WP_031436385	DNA topoisomerase [Methylobacter tundripaludum].	32.09	695	411	16	1	655	1	674	9e-92	314
rs:WP_013685590	DNA topoisomerase III [Fluviicola taffensis].	31.16	722	444	17	1	684	1	707	9e-92	312
rs:WP_015252793	DNA Topoisomerase III [Bacillus subtilis].	34.40	657	382	20	3	631	5	640	9e-92	312
rs:WP_015606321	DNA topoisomerase III [Salmonella enterica].	30.69	642	401	15	1	615	1	625	9e-92	311
rs:WP_041519455	DNA topoisomerase III [Flavobacterium hibernum].	31.86	700	409	22	1	661	1	671	1e-91	313
rs:WP_024084897	DNA topoisomerase III [Bacillus amyloliquefaciens].	34.75	659	377	22	3	631	5	640	1e-91	312
rs:WP_039435848	DNA topoisomerase III [Porphyromonas gulae].	29.88	686	438	16	1	655	1	674	1e-91	311
rs:WP_014662817	DNA topoisomerase III [Bacillus sp. JS].	34.25	657	383	20	3	631	5	640	1e-91	312
rs:WP_026648650	DNA topoisomerase III [Blautia wexlerae].	30.54	704	440	19	1	680	1	679	1e-91	311
rs:WP_015924446	DNA topoisomerase III [[Clostridium] cellulolyticum].	32.62	656	387	20	3	627	5	636	1e-91	312
rs:WP_034750284	DNA topoisomerase III [Chryseobacterium vrystaatense].	32.68	716	424	20	1	675	1	699	1e-91	311
rs:WP_020897137	DNA topoisomerase III [Winogradskyella psychrotolerans].	32.18	721	419	21	1	676	1	696	1e-91	313
rs:WP_039117708	DNA topoisomerase III [Flavobacterium sp. JRM].	31.40	726	415	25	1	680	1	689	1e-91	313
rs:WP_042566347	DNA topoisomerase III [Flavobacterium sp. MEB061].	31.71	719	422	25	1	680	1	689	1e-91	313
rs:WP_041850711	DNA topoisomerase III [Bacillus subtilis].	34.09	657	384	20	3	631	5	640	1e-91	312
rs:WP_004583756	DNA topoisomerase III [Porphyromonas gingivalis].	30.23	688	432	18	1	655	1	673	1e-91	311
rs:WP_008982747	DNA topoisomerase III [Ruminococcaceae bacterium D16].	30.68	691	436	15	1	671	3	670	1e-91	311
rs:WP_004620647	DNA topoisomerase III [[Clostridium] papyrosolvens].	32.47	656	389	20	3	627	5	637	1e-91	312
rs:WP_035674309	DNA topoisomerase III [Flavobacterium sp. 83].	31.21	737	421	23	1	684	1	704	1e-91	313
rs:WP_029447957	DNA topoisomerase III [Cellulophaga baltica].	31.66	717	427	20	1	680	1	691	1e-91	313
rs:WP_034705127	DNA topoisomerase III [Chryseobacterium luteum].	33.05	711	424	20	1	673	1	697	1e-91	311
rs:WP_003240282	DNA topoisomerase III [Bacillus subtilis].	34.25	657	383	20	3	631	5	640	1e-91	312
gpu:CP007165_390	DNA topoisomerase III [Bacillus amyloliquefaciens subsp. plantarum NJN6]	34.75	659	377	22	3	631	13	648	1e-91	312
rs:WP_027376452	DNA topoisomerase III [Chryseobacterium palustre].	32.35	714	424	21	1	675	1	694	1e-91	311
rs:WP_007574002	DNA topoisomerase III [Prevotella multisaccharivorax].	31.64	670	406	16	1	630	1	658	1e-91	310
rs:WP_005935499	DNA topoisomerase III [Faecalibacterium prausnitzii].	30.73	703	437	15	1	671	3	687	2e-91	311
rs:WP_031378663	DNA topoisomerase III [Bacillus amyloliquefaciens].	34.60	659	378	22	3	631	5	640	2e-91	312
rs:WP_021481725	DNA topoisomerase III [Bacillus sp. EGD-AK10].	34.09	657	384	20	3	631	5	640	2e-91	311
rs:WP_034728006	DNA topoisomerase III [Chryseobacterium sp. JM1].	32.36	717	431	20	1	678	1	702	2e-91	311
rs:WP_029445302	DNA topoisomerase III [Cellulophaga baltica].	31.66	717	427	20	1	680	1	691	2e-91	313
rs:WP_037497697	DNA topoisomerase III, partial [Solirubrobacter soli].	29.55	714	447	22	3	679	5	699	2e-91	311
rs:WP_027374258	MULTISPECIES: DNA topoisomerase III [Chryseobacterium].	32.87	721	414	19	1	673	1	699	2e-91	311
rs:WP_039419614	DNA topoisomerase III [Porphyromonas gulae].	29.88	686	438	16	1	655	1	674	2e-91	310
rs:WP_009003584	DNA topoisomerase III [Clostridium sp. D5].	32.71	700	415	21	1	671	3	675	2e-91	311
rs:WP_038427393	DNA topoisomerase 3 [Bacillus subtilis].	34.14	659	381	21	3	631	5	640	2e-91	311
rs:WP_034678541	DNA topoisomerase III [Chryseobacterium formosense].	33.00	700	414	18	1	661	1	684	2e-91	311
rs:WP_032726499	DNA topoisomerase III [Bacillus subtilis].	34.09	657	384	20	3	631	5	640	2e-91	311
rs:WP_039432547	DNA topoisomerase III [Porphyromonas gulae].	29.88	686	438	16	1	655	1	674	2e-91	310
rs:WP_027428651	DNA topoisomerase III [Lachnospiraceae bacterium AD3010].	31.93	689	430	16	1	673	1	666	2e-91	311
rs:WP_036082282	DNA topoisomerase III [Listeria cornellensis].	33.80	642	384	17	3	627	5	622	2e-91	311
rs:WP_041351795	DNA topoisomerase III [Bacillus subtilis].	34.45	659	379	21	3	631	5	640	2e-91	311
rs:WP_029317313	DNA topoisomerase 3 [Bacillus subtilis].	34.09	657	384	20	3	631	5	640	2e-91	311
sp:TOP3_BACSU	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	34.25	657	383	20	3	631	5	640	2e-91	311
rs:WP_004381429	DNA topoisomerase III [Prevotella oulorum].	31.52	682	393	17	1	624	1	666	2e-91	310
rs:WP_016289142	DNA topoisomerase III [Lachnospiraceae bacterium 3-1].	29.75	716	442	20	1	683	1	688	2e-91	311
rs:WP_022149832	DNA topoisomerase III [Prevotella sp. CAG:1320].	32.69	618	378	15	1	593	1	605	3e-91	311
rs:WP_025613987	DNA topoisomerase III [Cellulophaga baltica].	31.52	717	428	20	1	680	1	691	3e-91	312
rs:WP_040414532	DNA topoisomerase III [Cyclobacterium qasimii].	30.30	703	443	19	1	676	1	683	3e-91	312
rs:WP_039445782	DNA topoisomerase III [Porphyromonas gulae].	29.88	686	438	16	1	655	1	674	3e-91	310
rs:WP_027449112	DNA topoisomerase III [Prevotella brevis].	31.08	695	402	15	1	630	1	683	3e-91	310
rs:WP_038827751	DNA topoisomerase III [Bacillus subtilis].	34.09	657	384	20	3	631	5	640	3e-91	311
rs:WP_044161796	DNA topoisomerase III [Salinibacillus aidingensis].	34.09	657	384	21	3	631	5	640	3e-91	311
rs:WP_010521506	DNA topoisomerase III [Flavobacteriaceae bacterium HQM9].	31.56	716	426	22	1	676	1	692	3e-91	311
rs:WP_045091551	DNA topoisomerase III [Clostridium sp. FS41].	31.28	713	423	24	1	680	1	679	3e-91	310
rs:WP_016295429	DNA topoisomerase III [Lachnospiraceae bacterium M18-1].	31.32	696	427	19	1	671	1	670	3e-91	310
rs:WP_043858106	DNA topoisomerase III [Bacillus subtilis].	34.09	657	384	20	3	631	5	640	3e-91	311
rs:WP_003525508	DNA topoisomerase III [[Clostridium] clostridioforme].	30.50	695	434	17	1	671	3	672	3e-91	310
rs:WP_003509283	DNA topoisomerase III [[Clostridium] symbiosum].	30.26	694	437	16	2	671	4	674	4e-91	310
rs:WP_027126573	DNA topoisomerase III [Gelidibacter mesophilus].	31.56	713	423	23	1	676	1	685	4e-91	311
rs:WP_014112696	DNA topoisomerase III [Bacillus subtilis].	34.09	657	384	20	3	631	5	640	4e-91	311
rs:WP_042977129	DNA topoisomerase III [Bacillus subtilis].	34.09	657	384	20	3	631	5	640	4e-91	311
tr:K1V4F0_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC78771.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EKC78771.1};	30.26	717	437	20	1	683	1	688	4e-91	310
rs:WP_006638741	DNA topoisomerase III [Bacillus sonorensis].	34.62	650	382	19	3	627	5	636	4e-91	311
rs:WP_038507278	DNA topoisomerase III [Cellulophaga lytica].	31.31	709	430	23	1	676	1	685	4e-91	311
rs:WP_010333072	DNA topoisomerase III [Bacillus mojavensis].	34.09	657	384	21	3	631	5	640	5e-91	310
tr:K0WYG1_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJZ64257.1};	31.62	699	408	17	1	652	31	706	5e-91	310
rs:WP_014478870	DNA topoisomerase III [Bacillus subtilis].	34.09	657	384	20	3	631	5	640	5e-91	310
rs:WP_013625182	DNA topoisomerase III [Syntrophobotulus glycolicus].	33.03	657	384	17	3	627	5	637	5e-91	310
rs:WP_040296029	DNA topoisomerase III [Barnesiella intestinihominis].	31.62	699	408	17	1	652	1	676	5e-91	309
rs:WP_018474722	hypothetical protein [Echinicola pacifica].	30.62	725	436	22	1	678	1	705	6e-91	311
rs:WP_036132497	DNA topoisomerase III [Listeriaceae bacterium FSL A5-0209].	33.96	642	383	17	3	627	5	622	6e-91	310
rs:WP_003225098	DNA topoisomerase III [Bacillus subtilis].	34.25	657	383	20	3	631	5	640	6e-91	310
rs:WP_009324599	DNA topoisomerase III [Subdoligranulum sp. 4_3_54A2FAA].	30.40	694	436	16	2	671	4	674	6e-91	309
rs:WP_025284251	DNA topoisomerase III [Bacillus amyloliquefaciens].	34.60	659	378	22	3	631	5	640	7e-91	310
rs:WP_046311290	DNA topoisomerase III [Pontibacter korlensis].	30.28	743	443	21	1	687	1	724	7e-91	312
rs:WP_039427007	DNA topoisomerase III [Porphyromonas gulae].	30.38	688	431	19	1	655	1	673	7e-91	309
rs:WP_036734273	DNA topoisomerase III [Peptococcaceae bacterium SCADC1_2_3].	33.28	655	381	23	3	626	4	633	7e-91	309
rs:WP_004081256	DNA topoisomerase III [Clostridium sp. ASF502].	32.67	701	416	21	2	673	4	677	7e-91	309
rs:WP_003156261	MULTISPECIES: DNA topoisomerase III [Bacillales].	34.60	659	378	22	3	631	5	640	7e-91	310
tr:I2C1H1_BACAM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	34.60	659	378	22	3	631	15	650	7e-91	310
rs:WP_035619101	DNA topoisomerase III [Flavobacterium hydatis].	31.04	728	415	24	1	680	1	689	8e-91	311
rs:WP_045383398	DNA topoisomerase III [Bacillus subtilis].	34.25	657	383	20	3	631	5	640	8e-91	310
rs:WP_002455007	DNA topoisomerase III [Staphylococcus hominis].	34.08	628	376	17	3	615	4	608	8e-91	310
rs:WP_034645991	DNA topoisomerase III [Cellulophaga geojensis].	31.31	709	430	23	1	676	1	685	8e-91	311
rs:WP_026462624	DNA topoisomerase III [Adhaeribacter aquaticus].	30.98	723	421	21	1	670	1	698	8e-91	312
rs:WP_024120262	DNA topoisomerase III [Bacillus mojavensis].	34.09	657	384	21	3	631	5	640	8e-91	310
rs:WP_038529514	DNA topoisomerase III [Formosa agariphila].	31.04	712	428	22	1	676	1	685	8e-91	311
rs:WP_038462366	MULTISPECIES: DNA topoisomerase III [Bacillus subtilis group].	34.60	659	378	22	3	631	5	640	8e-91	310
rs:WP_016316312	DNA topoisomerase III [Anaerotruncus sp. G3(2012)].	32.10	701	413	22	2	671	3	671	8e-91	309
rs:WP_015239170	DNA topoisomerase III [Bacillus amyloliquefaciens].	34.60	659	378	22	3	631	5	640	8e-91	310
tr:S6FW61_BACAM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	34.60	659	378	22	3	631	15	650	9e-91	310
rs:WP_047097004	DNA topoisomerase III [Chryseobacterium indologenes].	32.96	719	414	19	1	673	1	697	9e-91	309
rs:WP_007410181	DNA topoisomerase III [Bacillus sp. 916].	34.60	659	378	22	3	631	5	640	9e-91	310
rs:WP_012116832	DNA topoisomerase III [Bacillus amyloliquefaciens].	34.60	659	378	22	3	631	5	640	9e-91	310
rs:WP_039421649	DNA topoisomerase III [Porphyromonas gulae].	29.74	686	439	16	1	655	1	674	9e-91	308
rs:WP_026092310	DNA topoisomerase III [Bacillus amyloliquefaciens].	34.60	659	378	22	3	631	5	640	9e-91	310
rs:WP_044053591	DNA topoisomerase III [Bacillus subtilis].	34.55	660	378	22	3	631	5	641	9e-91	310
rs:WP_024990268	DNA topoisomerase III [Prevotella albensis].	31.07	692	400	17	1	629	1	678	9e-91	308
rs:WP_016304287	DNA topoisomerase III [Lachnospiraceae bacterium A2].	31.75	693	428	18	1	671	1	670	9e-91	309
rs:WP_038460655	MULTISPECIES: DNA topoisomerase III [Bacillus subtilis group].	34.55	657	381	21	3	631	5	640	9e-91	310
gp:CP006845_416	DNA topoisomerase III [Bacillus amyloliquefaciens CC178]	34.60	659	378	22	3	631	13	648	1e-90	310
gp:HE774679_385	DNA topoisomerase III [Bacillus amyloliquefaciens subsp. plantarum YAU B9601-Y2]	34.60	659	378	22	3	631	13	648	1e-90	310
gp:CP006890_411	DNA topoisomerase III [Bacillus amyloliquefaciens SQR9]	34.60	659	378	22	3	631	15	650	1e-90	310
rs:WP_032870446	MULTISPECIES: DNA topoisomerase III [Bacillus].	34.60	659	378	22	3	631	5	640	1e-90	310
rs:WP_036851975	DNA topoisomerase III [Porphyromonas macacae].	31.16	674	422	17	1	647	1	659	1e-90	308
tr:A0A0E1NYZ3_BACAM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AJK64203.1};	34.60	659	378	22	3	631	15	650	1e-90	310
rs:WP_027454557	DNA topoisomerase III [Prevotella brevis].	30.79	695	404	15	1	630	1	683	1e-90	309
rs:WP_006282052	DNA topoisomerase III [Prevotella bryantii].	31.32	696	392	17	1	625	1	681	1e-90	309
rs:WP_019257504	DNA topoisomerase III [Bacillus subtilis].	34.09	657	384	20	3	631	5	640	1e-90	310
rs:WP_025491694	DNA topoisomerase III [Clostridiales bacterium VE202-27].	30.22	695	436	17	1	671	3	672	1e-90	309
rs:WP_002368714	MULTISPECIES: DNA topoisomerase III [Enterococcus].	30.80	711	442	18	1	683	1	689	1e-90	309
rs:WP_009296637	DNA topoisomerase III [Clostridium sp. 7_3_54FAA].	30.26	694	437	17	2	671	4	674	1e-90	309
rs:WP_029326219	MULTISPECIES: DNA topoisomerase III [Bacillus].	34.60	659	378	22	3	631	5	640	1e-90	310
rs:WP_036892672	DNA topoisomerase III [Prevotella sp. S7-1-8].	32.69	618	379	15	1	594	1	605	1e-90	309
rs:WP_045926222	DNA topoisomerase III [Bacillus siamensis].	34.25	657	383	20	3	631	5	640	1e-90	310
rs:WP_002576397	DNA topoisomerase III [[Clostridium] bolteae].	30.59	716	422	23	1	679	1	678	1e-90	308
rs:WP_027400099	DNA topoisomerase III [Anaerovorax odorimutans].	32.51	726	400	23	1	673	1	689	1e-90	309
rs:WP_004802669	DNA topoisomerase III [Eggerthia catenaformis].	32.54	710	422	21	1	683	1	680	1e-90	308
rs:WP_034103981	DNA topoisomerase III [Desulfotomaculum sp. BICA1-6].	32.77	653	387	19	3	627	4	632	1e-90	308
tr:I2HML6_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	34.60	659	378	22	3	631	15	650	1e-90	310
rs:WP_045509010	DNA topoisomerase III [Bacillus amyloliquefaciens].	34.45	659	379	22	3	631	5	640	1e-90	309
rs:WP_019713359	DNA topoisomerase III [Bacillus subtilis].	34.09	657	384	20	3	631	5	640	1e-90	309
rs:WP_024714484	DNA topoisomerase III [Bacillus tequilensis].	34.34	661	376	21	3	630	5	640	1e-90	309
rs:WP_010330854	DNA topoisomerase III [Bacillus vallismortis].	34.40	657	382	20	3	631	5	640	2e-90	309
rs:WP_046160064	DNA topoisomerase III [Bacillus sp. CMAA 1185].	34.14	659	381	21	3	631	5	640	2e-90	309
rs:WP_017498188	DNA topoisomerase III [Flavobacterium sp. WG21].	31.15	719	426	22	1	680	1	689	2e-90	310
rs:WP_022163221	DNA topoisomerase III [Bacteroides sp. CAG:633].	31.49	651	389	14	1	603	1	642	2e-90	309
rs:WP_028870997	DNA topoisomerase III [Psychroserpens burtonensis].	32.73	721	413	23	1	680	1	690	2e-90	310
rs:WP_041941796	DNA topoisomerase, partial [Waddlia chondrophila].	31.37	663	418	15	1	652	1	637	2e-90	307
rs:WP_021851957	DNA topoisomerase III [Prevotella sp. CAG:1058].	33.12	625	374	15	1	603	1	603	2e-90	308
rs:WP_032866976	DNA topoisomerase III [Bacillus amyloliquefaciens].	34.60	659	378	22	3	631	5	640	2e-90	309
rs:WP_003505019	DNA topoisomerase III [[Clostridium] symbiosum].	29.78	695	441	17	1	671	3	674	2e-90	308
rs:WP_009581364	DNA topoisomerase III [Fulvivirga imtechensis].	30.91	715	425	23	1	673	1	688	2e-90	310
rs:WP_032989883	DNA topoisomerase III [Cronobacter sakazakii].	32.38	661	384	23	1	622	1	637	2e-90	307
rs:WP_028900129	DNA topoisomerase III [Prevotella sp. HJM029].	33.33	618	368	15	1	592	1	600	2e-90	308
tr:D3ABL1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	30.01	693	434	17	5	671	1	668	2e-90	308
rs:WP_010235392	DNA topoisomerase III [Clostridium arbusti].	32.31	650	399	19	3	627	5	638	2e-90	309
tr:W7DPX5_9LIST	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.64	642	385	17	3	627	5	622	2e-90	308
rs:WP_027391237	DNA topoisomerase III [Aquimarina latercula].	31.31	709	432	21	1	676	1	687	2e-90	310
rs:WP_036093033	DNA topoisomerase III [Listeria newyorkensis].	33.64	642	385	17	3	627	5	622	2e-90	308
tr:F8LD86_9CHLA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.07	663	420	14	1	652	1	637	2e-90	307
rs:WP_014469759	DNA topoisomerase III [Bacillus amyloliquefaciens].	34.40	657	382	21	3	631	5	640	2e-90	309
rs:WP_029575269	DNA topoisomerase III [Bacillus siamensis].	34.45	659	379	22	3	631	5	640	2e-90	308
rs:WP_044039668	DNA topoisomerase III [Clostridium sp. M2/40].	33.69	647	388	17	2	627	3	629	2e-90	308
rs:WP_008462312	DNA topoisomerase III [Flavobacterium sp. F52].	31.46	728	414	23	1	680	1	691	3e-90	310
rs:WP_002977772	DNA topoisomerase III [Chryseobacterium gleum].	33.10	716	417	18	1	673	1	697	3e-90	308
rs:WP_009249981	DNA topoisomerase III [Lachnospiraceae bacterium 3_1_57FAA_CT1].	29.92	712	446	19	1	683	1	688	3e-90	308
rs:WP_008689666	DNA topoisomerase III [Eubacterium sp. 3_1_31].	30.26	694	437	17	2	671	4	674	3e-90	308
rs:WP_042222299	DNA topoisomerase III [Oceanobacillus manasiensis].	33.23	647	392	17	3	626	5	634	3e-90	308
rs:WP_041904784	DNA topoisomerase III [Bacillus sp. BSC154].	34.25	657	383	20	3	631	5	640	3e-90	308
rs:WP_026667054	MULTISPECIES: DNA topoisomerase III [Butyrivibrio].	32.04	696	414	19	2	673	4	664	3e-90	308
rs:WP_009004429	DNA topoisomerase III [Clostridium sp. D5].	30.19	699	435	17	3	671	7	682	3e-90	308
rs:WP_027879013	DNA topoisomerase III [Mesoflavibacter zeaxanthinifaciens].	31.52	717	420	24	1	676	1	687	3e-90	309
rs:WP_028608020	DNA topoisomerase III [Olleya sp. VCSM12].	31.61	715	421	21	1	676	1	686	3e-90	309
rs:WP_040441619	hypothetical protein, partial [Alicyclobacillus acidoterrestris].	30.09	698	448	18	1	673	1	683	3e-90	307
rs:WP_015267562	DNA topoisomerase III [Echinicola vietnamensis].	30.29	723	440	22	1	678	1	704	3e-90	310
rs:WP_016991292	DNA topoisomerase III [Flavobacterium sp. ACAM 123].	31.41	710	436	20	1	680	1	689	3e-90	309
rs:WP_039254980	DNA topoisomerase III [Bacillus sp. Pc3].	34.45	659	379	22	3	631	5	640	3e-90	308
rs:WP_029055860	DNA topoisomerase III [Staphylococcus sp. URHA0057].	35.51	628	368	18	3	615	4	609	3e-90	308
rs:WP_031304488	DNA topoisomerase III [Bacillus amyloliquefaciens].	34.45	659	379	22	3	631	5	640	3e-90	308
rs:WP_013351049	MULTISPECIES: DNA topoisomerase III [Bacillus subtilis group].	34.40	657	382	21	3	631	5	640	4e-90	308
rs:WP_041481943	DNA topoisomerase III [Bacillus amyloliquefaciens].	34.45	659	379	22	3	631	5	640	4e-90	308
gpu:CP011686_415	DNA topoisomerase III [Bacillus amyloliquefaciens]	34.45	659	379	22	3	631	15	650	4e-90	308
rs:WP_002578949	MULTISPECIES: DNA topoisomerase III [Firmicutes].	30.53	701	436	19	1	678	1	673	4e-90	307
rs:WP_044225363	DNA topoisomerase III [Coprobacter sp. 177].	31.11	733	417	20	1	663	1	715	4e-90	308
rs:WP_039429215	DNA topoisomerase III [Porphyromonas sp. COT-052 OH4946].	29.59	686	440	16	1	655	1	674	4e-90	307
rs:WP_036304041	DNA topoisomerase [Methylomicrobium agile].	30.58	690	442	18	1	676	1	667	4e-90	307
rs:WP_015382801	DNA topoisomerase III [Bacillus subtilis].	33.99	659	382	21	3	631	5	640	4e-90	308
rs:WP_043867614	DNA topoisomerase III [Bacillus amyloliquefaciens].	34.45	659	379	22	3	631	5	640	5e-90	308
rs:WP_009988109	DNA topoisomerase III [Ruminococcus flavefaciens].	31.06	689	430	17	3	675	4	663	5e-90	306
tr:E8LH21_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.53	701	436	19	1	678	3	675	5e-90	307
rs:WP_009296552	DNA topoisomerase III [Clostridium sp. 7_3_54FAA].	30.17	696	435	17	2	671	4	674	5e-90	307
rs:WP_009983779	DNA topoisomerase III [Ruminococcus flavefaciens].	31.84	691	422	20	3	675	4	663	5e-90	306
rs:WP_018361007	DNA topoisomerase III [Porphyromonas macacae].	31.07	676	423	17	1	648	1	661	5e-90	306
rs:WP_018595759	DNA topoisomerase III [Blautia producta].	29.97	694	439	17	2	671	4	674	5e-90	307
rs:WP_022411924	DNA topoisomerase III [Ruminococcus sp. CAG:330].	32.15	675	416	16	1	657	1	651	5e-90	306
rs:WP_040578486	DNA topoisomerase, partial [Methylomicrobium album].	30.58	690	442	18	1	676	1	667	5e-90	306
rs:WP_039148623	DNA topoisomerase III [Gallibacterium anatis].	30.67	639	396	15	1	614	1	617	5e-90	306
rs:WP_045635658	DNA topoisomerase III [Peptococcaceae bacterium BRH_c4a].	32.92	653	392	19	3	630	4	635	5e-90	306
tr:T0BQW9_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.09	698	448	18	1	673	1	683	5e-90	307
gp:HE617159_384	DNA topoisomerase III [Bacillus amyloliquefaciens subsp. plantarum CAU B946]	34.14	659	381	21	3	631	13	648	6e-90	308
rs:WP_010531156	DNA topoisomerase III [Lentibacillus jeotgali].	31.62	718	435	18	3	681	5	705	6e-90	307
rs:WP_041918412	DNA topoisomerase III [Listeria innocua].	33.18	651	378	19	3	627	5	624	6e-90	307
rs:WP_045644923	DNA topoisomerase III [Peptococcaceae bacterium BRH_c4b].	32.34	671	386	18	3	630	4	649	6e-90	307
tr:H8GM49_METAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.58	690	442	18	1	676	1	667	6e-90	306
rs:WP_031411082	DNA topoisomerase III [Brevibacillus laterosporus].	32.62	653	396	18	2	627	4	639	6e-90	308
rs:WP_038562834	DNA topoisomerase III [Draconibacterium orientale].	30.65	708	423	20	1	661	1	687	6e-90	309
rs:WP_003772809	DNA topoisomerase III [Listeria innocua].	33.18	651	378	19	3	627	5	624	6e-90	307
gpu:CP009928_37	DNA topoisomerase III [Chryseobacterium gallinarum]	33.24	713	420	18	1	673	1	697	6e-90	307
rs:WP_036910457	DNA topoisomerase III, partial [Prevotella sp. FD3004].	33.23	623	365	19	1	590	1	605	6e-90	305
rs:WP_045029767	DNA topoisomerase III [Draconibacterium sp. JN14CK-3].	29.97	704	436	18	1	668	1	683	7e-90	308
rs:WP_039890715	DNA topoisomerase III [[Clostridium] hathewayi].	29.87	693	435	17	5	671	1	668	7e-90	306
rs:WP_022600591	DNA topoisomerase III [Coprobacter fastidiosus].	30.98	707	414	19	1	652	1	688	7e-90	306
rs:WP_013620522	DNA topoisomerase III [Cellulophaga lytica].	31.17	709	431	23	1	676	1	685	7e-90	308
rs:WP_028290036	DNA topoisomerase III [Olleya sp. VCSA23].	31.79	711	425	20	1	676	1	686	7e-90	308
rs:WP_041336817	DNA topoisomerase III [Bacillus subtilis].	33.94	657	385	20	3	631	5	640	7e-90	307
rs:WP_016316298	DNA topoisomerase III [Anaerotruncus sp. G3(2012)].	30.40	694	436	16	2	671	4	674	7e-90	306
rs:WP_036097359	DNA topoisomerase III [Listeria floridensis].	33.28	643	389	17	3	627	5	625	8e-90	307
rs:WP_022129902	DNA topoisomerase III [Bacteroides sp. CAG:530].	31.99	672	401	19	1	630	1	658	8e-90	306
rs:WP_001241569	DNA topoisomerase III [Salmonella enterica].	30.09	638	410	13	1	615	1	625	8e-90	306
rs:WP_027412801	DNA topoisomerase III [Aquimarina muelleri].	31.40	707	432	22	1	676	1	685	8e-90	308
rs:WP_007134283	DNA topoisomerase III [Prevotella salivae].	32.10	704	382	20	1	624	1	688	9e-90	306
rs:WP_013745196	DNA topoisomerase III [Gallibacterium anatis].	31.08	637	396	14	1	614	1	617	9e-90	305
rs:WP_041101489	DNA topoisomerase III [Bacillus badius].	33.23	647	389	19	3	627	5	630	9e-90	307
rs:WP_034058450	DNA topoisomerase III [Lacinutrix sp. PAMC 27137].	31.35	721	418	23	1	676	1	689	9e-90	308
tr:A0A086F9L8_9FLAO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KFF75632.1};	33.24	713	420	18	1	673	1	697	9e-90	306
rs:WP_007808804	DNA topoisomerase III [Flavobacterium sp. CF136].	31.68	726	413	25	1	680	1	689	1e-89	308
rs:WP_009316961	DNA topoisomerase III [Tannerella sp. 6_1_58FAA_CT1].	30.77	702	422	16	1	652	1	688	1e-89	306
rs:WP_002448594	DNA topoisomerase III [Staphylococcus hominis].	34.13	630	373	18	3	615	4	608	1e-89	306
rs:WP_026752833	DNA topoisomerase III [Sediminibacter sp. Hel_I_10].	32.68	716	414	23	1	676	1	688	1e-89	308
tr:G5QPK6_SALRU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.82	684	433	17	1	650	1	671	1e-89	306
rs:WP_043895468	DNA topoisomerase III [Porphyromonas gingivalis].	30.38	688	431	18	1	655	1	673	1e-89	306
rs:WP_036873209	DNA topoisomerase III [Porphyromonas macacae].	31.07	676	423	17	1	648	1	661	1e-89	305
rs:WP_020082018	DNA topoisomerase III [Flavobacterium sp. SCGC AAA160-P02].	30.22	728	437	19	1	683	1	702	1e-89	308
rs:WP_045461521	DNA topoisomerase III [Sporocytophaga myxococcoides].	32.55	719	426	21	1	676	1	703	1e-89	309
rs:WP_012024355	DNA topoisomerase III [Flavobacterium johnsoniae].	31.15	719	426	24	1	680	1	689	1e-89	308
rs:WP_047182112	DNA topoisomerase III [Bacillus subtilis].	33.84	659	383	21	3	631	5	640	1e-89	307
rs:WP_026729058	DNA topoisomerase III [Flavobacterium denitrificans].	31.04	728	417	23	1	680	1	691	1e-89	308
rs:WP_041114359	DNA topoisomerase III [Bacillus badius].	33.23	647	389	19	3	627	5	630	1e-89	306
rs:WP_010422921	DNA topoisomerase III [Anaerophaga thermohalophila].	31.66	717	431	19	1	678	1	697	1e-89	308
rs:WP_044930836	DNA topoisomerase III [Clostridium sp. M62/1].	30.52	711	429	23	1	679	1	678	1e-89	306
rs:WP_014471442	DNA topoisomerase III [Bacillus amyloliquefaciens].	34.25	657	383	21	3	631	5	640	1e-89	307
rs:WP_022405198	DNA topoisomerase III [Prevotella sp. CAG:485].	31.49	616	386	13	1	592	1	604	1e-89	304
rs:WP_040473791	DNA topoisomerase III [Flavobacterium frigoris].	31.13	726	417	24	1	680	1	689	1e-89	308
rs:WP_022391175	DNA topoisomerase III [Tannerella sp. CAG:51].	31.18	712	406	20	1	652	1	688	1e-89	306
rs:WP_008707174	DNA topoisomerase III [Rhodopirellula maiorica].	31.90	674	413	14	1	652	1	650	1e-89	309
rs:WP_045499150	DNA topoisomerase III [Chryseobacterium sp. StRB126].	32.72	709	407	19	1	661	1	687	1e-89	306
rs:WP_033575096	DNA topoisomerase III [Bacillus amyloliquefaciens].	34.40	657	382	21	3	631	5	640	1e-89	306
rs:WP_046976083	DNA topoisomerase III [Photorhabdus temperata].	33.82	618	356	20	1	581	1	602	1e-89	304
rs:WP_024573010	DNA topoisomerase III [Bacillus subtilis].	33.79	657	386	20	3	631	5	640	1e-89	306
rs:WP_016303791	DNA topoisomerase III [Lachnospiraceae bacterium A2].	30.32	709	448	19	1	683	1	689	1e-89	306
rs:WP_014729094	DNA topoisomerase III [Cronobacter sakazakii].	32.07	661	386	23	1	622	1	637	1e-89	305
rs:WP_007893951	DNA topoisomerase III [Cronobacter sakazakii].	32.07	661	386	23	1	622	1	637	2e-89	304
rs:WP_044001639	DNA topoisomerase III [Hymenobacter swuensis].	28.17	756	458	18	1	684	1	743	2e-89	309
rs:WP_028121874	DNA topoisomerase III [Epilithonimonas tenax].	33.04	681	405	19	1	647	1	664	2e-89	306
rs:WP_043894827	DNA topoisomerase III [Porphyromonas gingivalis].	30.09	688	433	18	1	655	1	673	2e-89	305
rs:WP_021963596	DNA topoisomerase III [Prevotella sp. CAG:1185].	32.91	623	378	13	1	603	1	603	2e-89	306
rs:WP_034664011	DNA topoisomerase III [Bacillus pumilus].	33.33	648	393	17	3	627	5	636	2e-89	306
rs:WP_029471079	DNA topoisomerase III [Clostridiales bacterium VE202-06].	29.79	715	443	19	1	683	1	688	2e-89	306
rs:WP_005875378	DNA topoisomerase III [Porphyromonas gingivalis].	30.09	688	433	18	1	655	1	673	2e-89	305
rs:WP_003440585	DNA topoisomerase III [Clostridium pasteurianum].	32.92	650	395	19	3	627	5	638	2e-89	306
rs:WP_022357530	DNA topoisomerase III [Ruminococcus sp. CAG:379].	30.31	673	427	14	1	655	1	649	2e-89	305
rs:WP_043895884	DNA topoisomerase III [Porphyromonas gingivalis].	30.09	688	433	18	1	655	1	673	2e-89	305
rs:WP_039158592	DNA topoisomerase III [Gallibacterium anatis].	30.46	637	400	14	1	614	1	617	2e-89	304
rs:WP_043894242	DNA topoisomerase III [Porphyromonas gingivalis].	30.09	688	433	18	1	655	1	673	2e-89	305
tr:U2LGV2_PORGN	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERJ88694.1};	30.38	688	431	18	1	655	16	688	2e-89	305
rs:WP_027066133	DNA topoisomerase III [Maribacter sp. Hel_I_7].	31.43	719	426	22	1	680	1	691	2e-89	307
rs:WP_009259780	DNA topoisomerase III [Lachnospiraceae bacterium 7_1_58FAA].	30.46	696	428	18	1	671	2	666	2e-89	305
rs:WP_021824609	DNA topoisomerase III [Prevotella salivae].	31.96	704	383	20	1	624	1	688	2e-89	305
rs:WP_016317940	DNA topoisomerase III [Anaerotruncus sp. G3(2012)].	30.81	701	425	22	1	671	1	671	2e-89	305
rs:WP_018347287	MULTISPECIES: DNA topoisomerase III [Gallibacterium].	30.52	639	397	15	1	614	1	617	2e-89	304
rs:WP_035393366	MULTISPECIES: DNA topoisomerase III [Clostridiales].	30.28	710	432	22	1	679	1	678	2e-89	305
rs:WP_033533770	DNA topoisomerase III [Listeria innocua].	33.18	651	378	19	3	627	5	624	2e-89	306
tr:H7FRM8_9FLAO	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.13	726	417	24	1	680	10	698	2e-89	307
tr:K8B175_9ENTR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.47	619	363	20	1	581	1	602	2e-89	304
rs:WP_036060571	DNA topoisomerase III [Listeria weihenstephanensis].	33.80	642	384	17	3	627	5	622	3e-89	305
rs:WP_009624172	DNA topoisomerase III [Desulfosporosinus sp. OT].	32.82	652	391	18	3	627	5	636	3e-89	306
gp:HF563562_395	DNA topoisomerase III [Bacillus amyloliquefaciens subsp. plantarum UCMB5036]	34.45	659	379	22	3	631	15	650	3e-89	306
rs:WP_046130259	DNA topoisomerase III [Bacillus sp. TH008].	34.31	650	384	19	3	627	5	636	3e-89	306
rs:WP_007039216	DNA topoisomerase III [Thiorhodococcus drewsii].	29.41	731	452	20	2	680	3	721	3e-89	308
rs:WP_036837072	DNA topoisomerase III [Photorhabdus temperata].	33.66	618	357	20	1	581	1	602	3e-89	303
rs:WP_028386518	DNA topoisomerase [Legionella geestiana].	30.61	686	421	20	1	655	1	662	3e-89	304
rs:WP_039417509	DNA topoisomerase III [Porphyromonas gingivalis].	30.09	688	433	18	1	655	1	673	3e-89	305
rs:WP_028076707	DNA topoisomerase III [Solirubrobacterales bacterium URHD0059].	29.66	708	451	20	3	673	5	702	3e-89	306
rs:WP_034122483	DNA topoisomerase III [Peptococcaceae bacterium BICA1-7].	32.42	654	387	20	3	626	4	632	3e-89	305
rs:WP_039081120	DNA topoisomerase III [Gallibacterium anatis].	30.52	639	397	15	1	614	1	617	3e-89	304
rs:WP_018674293	DNA topoisomerase III [Brevibacillus laterosporus].	32.47	653	397	19	2	627	4	639	3e-89	306
rs:WP_021397960	DNA topoisomerase III family protein [Peptoclostridium difficile].	30.39	701	437	19	1	678	1	673	3e-89	305
rs:WP_021325539	DNA topoisomerase III [Photorhabdus temperata].	33.66	618	357	20	1	581	1	602	3e-89	303
rs:WP_035127158	DNA topoisomerase III, partial [Conexibacter woesei].	29.58	710	450	23	3	673	5	703	3e-89	305
rs:WP_039145124	DNA topoisomerase III [Gallibacterium anatis].	30.67	639	396	15	1	614	1	617	3e-89	304
rs:WP_039107208	DNA topoisomerase III [Flavobacterium sp. AED].	31.63	724	416	25	1	680	1	689	3e-89	306
rs:WP_046409534	DNA topoisomerase III [Bacteroides sp. N54.MGS-20].	31.86	700	405	19	1	652	1	676	3e-89	305
tr:D4CB69_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.52	711	429	23	1	679	18	695	3e-89	305
rs:WP_043889999	DNA topoisomerase III [Porphyromonas gingivalis].	30.23	688	432	18	1	655	1	673	3e-89	304
rs:WP_034697604	DNA topoisomerase III [Chryseobacterium sp. CF365].	32.68	713	424	18	1	673	1	697	4e-89	305
rs:WP_004072118	DNA topoisomerase III [Desulfobacter postgatei].	31.73	706	416	19	1	668	1	678	4e-89	305
tr:W1R7K4_PORGN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ETA26501.1};	30.09	688	433	18	1	655	16	688	4e-89	305
rs:WP_025604343	DNA topoisomerase III [Pontibacter actiniarum].	29.61	743	446	19	1	687	1	722	4e-89	307
rs:WP_029731804	DNA topoisomerase III [Dorea sp. AGR2135].	29.90	719	437	21	1	683	1	688	4e-89	305
rs:WP_017638522	DNA topoisomerase III [Staphylococcus sp. E463].	35.35	628	369	18	3	615	4	609	4e-89	305
rs:WP_014930286	DNA topoisomerase III [Listeria monocytogenes].	32.87	651	380	18	3	627	5	624	4e-89	305
tr:C7H2S2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.28	710	432	22	1	679	18	695	4e-89	305
rs:WP_005947007	DNA topoisomerase III [Blautia hydrogenotrophica].	30.12	694	438	16	2	671	4	674	4e-89	305
rs:WP_009435078	DNA topoisomerase III [Prevotella sp. oral taxon 306].	32.96	628	370	17	1	590	1	615	5e-89	303
rs:WP_036899393	DNA topoisomerase III [Prevotella sp. S7 MS 2].	31.99	697	390	19	1	630	1	680	5e-89	304
rs:WP_046467158	DNA topoisomerase III [Staphylococcus pasteuri].	35.35	628	369	18	3	615	4	609	5e-89	305
rs:WP_042506224	DNA topoisomerase III [Algibacter lectus].	31.69	710	426	22	1	676	1	685	5e-89	306
rs:WP_015613674	DNA topoisomerase III [Clostridium pasteurianum].	32.46	650	398	19	3	627	5	638	5e-89	305
rs:WP_033701090	DNA topoisomerase III, partial [Enterococcus faecium].	31.64	670	411	17	28	671	4	652	5e-89	304
tr:F2Q8P5_SALEE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.39	684	436	17	1	650	1	671	5e-89	303
rs:WP_046174720	DNA topoisomerase III [Domibacillus indicus].	33.44	655	375	21	3	627	5	628	5e-89	305
tr:F5X8C0_PORGT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:BAK24552.1};	30.23	688	432	18	1	655	16	688	6e-89	304
rs:WP_035416335	DNA topoisomerase III [Ferrimonas kyonanensis].	30.69	655	416	15	1	622	1	650	6e-89	303
rs:WP_002687992	DNA topoisomerase III [Bergeyella zoohelcum].	32.29	703	415	20	1	663	1	682	6e-89	304
rs:WP_022321312	DNA topoisomerase III [Parabacteroides merdae CAG:48].	30.78	705	419	18	1	653	1	688	6e-89	304
rs:WP_001094105	DNA topoisomerase III [Bacillus cereus].	31.67	720	432	21	3	680	4	705	6e-89	305
rs:WP_038859932	DNA topoisomerase III, partial [Cronobacter sakazakii].	32.58	620	361	21	1	581	1	602	6e-89	302
rs:WP_006783591	DNA topoisomerase III [Turicibacter sanguinis].	33.74	658	382	22	2	631	4	635	6e-89	305
rs:WP_035658874	DNA topoisomerase III [Flavobacterium sp. EM1321].	31.67	723	417	26	1	680	1	689	7e-89	306
rs:WP_035684265	DNA topoisomerase III [Flavobacterium reichenbachii].	31.29	719	425	24	1	680	1	689	7e-89	306
rs:WP_046451949	DNA topoisomerase III [Bacteroides sp. UNK.MGS-14].	30.78	705	419	18	1	653	1	688	7e-89	304
rs:WP_019107256	DNA topoisomerase III [Peptoniphilus senegalensis].	34.52	591	344	13	1	579	1	560	7e-89	300
tr:A0A0E2LU45_PORGN	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERJ69010.1};	30.09	688	433	18	1	655	36	708	7e-89	304
rs:WP_042498112	hypothetical protein, partial [Algibacter lectus].	31.69	710	426	22	1	676	1	685	7e-89	306
rs:WP_004386618	DNA topoisomerase III, partial [Cronobacter sakazakii].	32.58	620	361	21	1	581	1	602	7e-89	302
rs:WP_029334830	DNA topoisomerase III [Exiguobacterium aurantiacum].	32.09	698	412	20	1	655	1	679	7e-89	304
rs:WP_045474264	DNA topoisomerase III [Winogradskyella sp. PG-2].	31.75	715	420	22	1	676	1	686	7e-89	305
rs:WP_002662996	DNA topoisomerase III [Bergeyella zoohelcum].	32.15	703	416	19	1	663	1	682	7e-89	304
rs:WP_043894029	DNA topoisomerase III [Porphyromonas gingivalis].	30.09	688	433	18	1	655	1	673	8e-89	303
rs:WP_014931756	DNA topoisomerase III [Listeria monocytogenes].	33.18	651	378	18	3	627	5	624	8e-89	304
rs:WP_013444792	DNA topoisomerase III [Paludibacter propionicigenes].	33.03	657	390	19	1	630	1	634	8e-89	302
rs:WP_006951164	DNA topoisomerase III [Prevotella micans].	31.91	611	382	15	1	590	1	598	8e-89	301
tr:B2RH95_PORG3	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:BAG32740.1};	30.09	688	433	18	1	655	36	708	8e-89	304
rs:WP_022746718	DNA topoisomerase 3 [Clostridium saccharobutylicum].	33.08	650	394	17	3	627	5	638	8e-89	305
rs:WP_040047798	DNA topoisomerase III [Bacillaceae bacterium MTCC 8252].	33.28	652	382	20	3	627	5	630	8e-89	304
rs:WP_005638697	DNA topoisomerase III [Parabacteroides merdae].	30.78	705	419	18	1	653	1	688	9e-89	303
rs:WP_014546985	DNA topoisomerase [Fibrobacter succinogenes].	30.12	737	441	18	1	673	1	727	9e-89	311
rs:WP_040037004	DNA topoisomerase III [Bacillaceae bacterium MTCC 10057].	33.28	652	382	20	3	627	5	630	9e-89	304
rs:WP_008901381	DNA topoisomerase [Peptoniphilus duerdenii].	34.52	591	344	13	1	579	1	560	9e-89	300
rs:WP_039234965	DNA topoisomerase III [Bacillus thermotolerans].	33.28	652	382	20	3	627	5	630	9e-89	304
rs:WP_021853873	DNA topoisomerase III [Prevotella sp. CAG:255].	33.07	623	377	13	1	603	1	603	9e-89	303
rs:WP_000047282	DNA topoisomerase III [Bacillus cereus].	34.76	656	375	22	3	627	5	638	9e-89	305
rs:WP_039089672	DNA topoisomerase III [Gallibacterium anatis].	30.77	637	398	14	1	614	1	617	9e-89	302
rs:WP_038883834	DNA topoisomerase III [Cronobacter dublinensis].	32.31	619	364	20	1	581	1	602	9e-89	302
rs:WP_011098708	DNA topoisomerase III [Clostridium tetani].	33.23	656	385	19	3	627	5	638	9e-89	305
rs:WP_017548815	DNA topoisomerase III [Salinicoccus carnicancri].	32.46	647	400	19	3	627	5	636	9e-89	304
rs:WP_005601674	DNA topoisomerase III [Butyrivibrio crossotus].	29.81	718	417	21	2	670	4	683	1e-88	304
tr:A0A0C2C2I1_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.28	652	382	20	3	627	16	641	1e-88	304
rs:WP_034545084	DNA topoisomerase [Clostridiales bacterium S7-1-4].	35.19	591	340	15	1	579	1	560	1e-88	300
rs:WP_038275861	DNA topoisomerase III [Yersinia ruckeri].	33.28	619	358	19	1	581	1	602	1e-88	302
rs:WP_036867434	DNA topoisomerase III [Porphyromonas canoris].	32.62	656	400	21	1	630	1	640	1e-88	303
rs:WP_004719880	DNA topoisomerase III [Yersinia ruckeri].	33.28	619	358	19	1	581	1	602	1e-88	302
rs:WP_045167716	DNA topoisomerase III [Prevotella intermedia].	32.74	620	375	13	1	590	1	608	1e-88	301
rs:WP_038888133	DNA topoisomerase III [Cronobacter dublinensis].	32.31	619	364	20	1	581	1	602	1e-88	302
rs:WP_044599963	DNA topoisomerase III [Cronobacter sakazakii].	32.58	620	361	21	1	581	1	602	1e-88	302
rs:WP_003732116	DNA topoisomerase III [Listeria monocytogenes].	33.13	652	377	18	3	627	5	624	1e-88	304
rs:WP_022328708	DNA topoisomerase III [Prevotella sp. CAG:732].	31.32	696	395	19	1	625	1	684	1e-88	303
rs:WP_027384776	DNA topoisomerase III [Chryseobacterium caeni].	32.75	681	406	19	1	647	1	663	1e-88	303
rs:WP_023240864	DNA topoisomerase III [Salmonella enterica].	29.89	639	405	15	1	613	1	622	1e-88	303
rs:WP_009011127	DNA topoisomerase III [Prevotella sp. C561].	32.17	628	371	13	1	591	1	610	1e-88	301
rs:WP_040249095	DNA topoisomerase III [Psychroserpens mesophilus].	31.85	719	418	22	1	676	1	690	1e-88	305
rs:WP_016220887	DNA topoisomerase III [Dorea sp. 5-2].	31.57	700	425	19	1	671	1	675	1e-88	303
rs:WP_019117159	MULTISPECIES: DNA topoisomerase III [Clostridiales].	34.52	591	344	13	1	579	1	560	1e-88	300
rs:WP_013994551	DNA topoisomerase III [Zobellia galactanivorans].	31.76	721	417	24	1	678	1	689	1e-88	305
rs:WP_026585960	DNA topoisomerase III [Bacillus sp. NSP9.1].	34.15	650	385	19	3	627	5	636	1e-88	304
rs:WP_031533880	MULTISPECIES: DNA topoisomerase III [Bacteroides].	30.56	697	402	17	1	629	1	683	1e-88	303
rs:WP_007649183	DNA topoisomerase III [Formosa sp. AK20].	31.37	714	429	21	1	676	1	691	1e-88	305
rs:WP_040155132	DNA topoisomerase III [Yersinia ruckeri].	33.28	619	358	19	1	581	1	602	1e-88	302
rs:WP_018108421	DNA topoisomerase III [Bacteroides propionicifaciens].	31.79	648	399	15	1	629	1	624	1e-88	301
rs:WP_023898920	MULTISPECIES: DNA topoisomerase III [Cronobacter].	31.92	661	387	23	1	622	1	637	1e-88	302
rs:WP_040581963	hypothetical protein [Sedimentibacter sp. B4].	32.05	699	416	20	1	660	1	679	1e-88	303
rs:WP_036764317	DNA topoisomerase [Peptostreptococcus sp. MV1].	34.52	591	344	13	1	579	1	560	1e-88	300
rs:WP_004083334	DNA topoisomerase III [Clostridium sp. ASF502].	28.95	715	449	18	1	683	1	688	1e-88	303
rs:WP_035649018	DNA topoisomerase III [Flavobacterium sp. Fl].	30.91	728	418	23	1	680	1	691	1e-88	305
rs:WP_014202755	DNA topoisomerase III [Owenweeksia hongkongensis].	30.62	712	444	20	1	678	1	696	2e-88	305
rs:WP_003727630	DNA topoisomerase III [Listeria monocytogenes].	33.13	652	377	18	3	627	5	624	2e-88	303
rs:WP_040446585	DNA topoisomerase III [Eubacterium ventriosum].	30.26	717	437	20	1	683	1	688	2e-88	303
rs:WP_028979020	DNA topoisomerase III [Sporocytophaga myxococcoides].	32.27	719	428	21	1	676	1	703	2e-88	305
rs:WP_003347899	DNA topoisomerase III [Bacillus methanolicus].	31.77	661	395	18	3	646	4	625	2e-88	303
rs:WP_003725309	DNA topoisomerase III [Listeria monocytogenes].	33.18	651	378	18	3	627	5	624	2e-88	303
rs:WP_016107448	DNA topoisomerase 3 [Bacillus cereus].	34.76	656	375	22	3	627	5	638	2e-88	304
tr:A0A099Y2H8_9FLAO	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.34	737	427	23	1	678	1	717	2e-88	304
rs:WP_003339104	DNA topoisomerase III [Brevibacillus laterosporus].	32.77	653	395	19	2	627	4	639	2e-88	304
rs:WP_021891241	DNA topoisomerase III, partial [Bacteroides sp. CAG:20].	31.57	700	407	18	1	652	27	702	2e-88	303
rs:WP_036849554	DNA topoisomerase III [Photorhabdus temperata].	33.66	618	357	20	1	581	1	602	2e-88	301
rs:WP_032993914	DNA topoisomerase III [Cronobacter malonaticus].	31.92	661	387	23	1	622	1	637	2e-88	301
rs:WP_025881445	DNA topoisomerase III [Prevotella baroniae].	32.40	605	373	12	1	581	1	593	2e-88	301
rs:WP_003730738	DNA topoisomerase III [Listeria monocytogenes].	33.69	653	372	19	3	627	5	624	2e-88	303
rs:WP_025065874	DNA topoisomerase III [Prevotella enoeca].	30.61	686	408	15	1	630	1	674	2e-88	302
rs:WP_032969960	DNA topoisomerase III [Cronobacter malonaticus].	31.92	661	387	23	1	622	1	637	2e-88	301
rs:WP_036845770	DNA topoisomerase III [Porphyromonas cangingivalis].	31.34	670	407	18	1	633	1	654	2e-88	301
rs:WP_000209238	DNA topoisomerase III [Bacillus cereus].	31.44	722	435	21	3	682	4	707	2e-88	303
rs:WP_006323417	DNA topoisomerase III [Anoxybacillus flavithermus].	30.71	723	455	18	1	687	1	713	2e-88	303
rs:WP_004838439	DNA topoisomerase [Anaerococcus vaginalis].	34.52	591	344	13	1	579	1	560	2e-88	299
rs:WP_038872642	DNA topoisomerase III [Cronobacter dublinensis].	32.15	619	365	20	1	581	1	602	2e-88	301
rs:WP_005644013	DNA topoisomerase III [Parabacteroides merdae].	30.21	705	423	16	1	653	1	688	2e-88	302
rs:WP_036881990	DNA topoisomerase III [Prevotella disiens].	32.64	622	374	14	1	592	1	607	2e-88	300
gp:AE017262_2719	DNA topoisomerase III [Listeria monocytogenes serotype 4b str. F2365]	33.18	651	378	18	3	627	5	624	2e-88	303
rs:WP_028396618	DNA topoisomerase III [Bacillus sp. FJAT-14578].	34.66	603	358	15	1	573	1	597	2e-88	303
rs:WP_015480086	DNA topoisomerase III [Polaribacter sp. MED152].	30.52	711	442	19	1	678	1	692	2e-88	304
tr:A0A090WWP2_9FLAO	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.69	710	426	22	1	676	1	685	3e-88	305
rs:WP_005956640	DNA topoisomerase III [Peptoniphilus harei].	34.35	591	345	13	1	579	1	560	3e-88	299
rs:WP_015298395	DNA topoisomerase III [Prevotella dentalis].	30.66	698	403	19	1	630	1	685	3e-88	302
rs:WP_000209237	DNA topoisomerase III [Bacillus cereus].	31.58	722	434	21	3	682	4	707	3e-88	303
rs:WP_042981626	DNA topoisomerase III [Bacillus mycoides].	34.10	654	382	21	3	627	5	638	3e-88	303
rs:WP_022584554	DNA topoisomerase III [Brevibacillus laterosporus].	32.77	653	395	19	2	627	4	639	3e-88	303
rs:WP_036823047	DNA topoisomerase III, partial [Polaribacter sp. Hel1_85].	31.34	737	427	23	1	678	1	717	3e-88	303
tr:A6NZE3_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.18	651	405	13	3	627	8	641	3e-88	303
rs:WP_014929276	DNA topoisomerase III [Listeria monocytogenes].	33.13	652	377	18	3	627	5	624	3e-88	303
rs:WP_010815313	DNA topoisomerase III [Enterococcus faecalis].	29.88	723	448	20	1	683	1	704	3e-88	303
rs:WP_024535645	DNA topoisomerase III [Sporosarcina sp. EUR3 2.2.2].	33.28	652	386	21	3	627	5	634	3e-88	303
rs:WP_012681475	DNA topoisomerase III [Listeria monocytogenes].	33.13	652	377	18	3	627	5	624	3e-88	303
rs:WP_046414281	DNA topoisomerase III [Bacteroides sp. UNK.MGS-13].	31.86	700	405	19	1	652	1	676	3e-88	302
rs:WP_014022468	DNA topoisomerase III [Cyclobacterium marinum].	29.68	711	453	19	1	684	1	691	3e-88	304
rs:WP_014929862	DNA topoisomerase III [Listeria monocytogenes].	33.18	651	378	18	3	627	5	624	3e-88	303
rs:WP_035111043	DNA topoisomerase III [Clostridium tetani].	33.08	656	386	19	3	627	5	638	3e-88	303
rs:WP_021932094	DNA topoisomerase III [Tannerella sp. CAG:118].	30.77	728	426	17	1	663	1	715	3e-88	303
rs:WP_004353362	DNA topoisomerase III [Prevotella denticola].	32.34	603	367	13	1	574	1	591	3e-88	300
rs:WP_036023794	DNA topoisomerase III [Leminorella grimontii].	33.33	627	347	18	1	581	1	602	3e-88	301
rs:WP_036774908	DNA topoisomerase III [Photorhabdus asymbiotica].	33.28	634	368	21	1	597	1	616	3e-88	301
rs:WP_004357490	DNA topoisomerase III [Prevotella disiens].	32.64	622	374	14	1	592	1	607	3e-88	300
rs:WP_046242841	DNA topoisomerase III [Hymenobacter sp. MIMtkLc17].	28.33	773	456	19	1	686	1	762	3e-88	306
rs:WP_027077441	DNA topoisomerase III [Maribacter antarcticus].	31.91	702	404	23	1	661	1	669	4e-88	304
rs:WP_016289972	DNA topoisomerase III [Lachnospiraceae bacterium 28-4].	31.33	699	426	19	2	671	5	678	4e-88	302
rs:WP_039507416	DNA topoisomerase III [Pectobacterium carotovorum].	30.65	646	397	14	1	614	1	627	4e-88	301
rs:WP_011563738	DNA topoisomerase III [Rubrobacter xylanophilus].	28.12	704	471	18	1	680	1	693	4e-88	302
rs:WP_014601552	DNA topoisomerase III [Listeria monocytogenes].	33.03	651	379	18	3	627	5	624	4e-88	302
rs:WP_009917426	DNA topoisomerase III [Listeria monocytogenes].	33.18	651	378	18	3	627	5	624	4e-88	302
rs:WP_025435565	DNA topoisomerase III [Eubacterium acidaminophilum].	32.93	668	389	22	3	635	5	648	4e-88	303
tr:K1RRE4_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC46094.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EKC46094.1};	30.26	717	437	20	1	683	1	688	4e-88	302
rs:WP_001263214	MULTISPECIES: DNA topoisomerase [Enterobacteriaceae].	32.23	667	404	14	1	629	1	657	4e-88	301
rs:WP_003335207	DNA topoisomerase III [Brevibacillus laterosporus].	32.77	653	395	19	2	627	4	639	4e-88	303
rs:WP_044063820	DNA topoisomerase III [Prevotella saccharolytica].	33.28	616	378	15	1	598	1	601	4e-88	301
rs:WP_025064416	DNA topoisomerase III [Prevotella disiens].	32.64	622	374	14	1	592	1	607	4e-88	300
rs:WP_041089158	DNA topoisomerase III [Bacillus pumilus].	33.23	653	387	19	3	627	5	636	4e-88	303
rs:WP_019842061	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	32.23	667	404	14	1	629	1	657	4e-88	301
rs:WP_021657564	DNA topoisomerase [Clostridiales bacterium oral taxon 876].	33.44	652	389	21	3	627	5	638	4e-88	303
rs:WP_040647434	DNA topoisomerase III [Pseudoflavonifractor capillosus].	31.18	651	405	13	3	627	5	638	4e-88	303
rs:WP_036854117	DNA topoisomerase III [Prevotella denticola].	32.34	603	367	13	1	574	1	591	5e-88	300
rs:WP_046513834	DNA topoisomerase III [Cryomorphaceae bacterium ASP10-05a].	30.10	711	440	20	1	678	1	687	5e-88	303
rs:WP_033811278	DNA topoisomerase [Escherichia coli].	32.38	667	403	15	1	629	1	657	5e-88	301
rs:WP_039176652	DNA topoisomerase III [Bacillus sp. WP8].	33.23	653	387	19	3	627	5	636	5e-88	302
rs:WP_002585004	MULTISPECIES: DNA topoisomerase III [Clostridiales].	32.43	703	409	20	1	671	1	669	5e-88	301
rs:WP_000047302	DNA topoisomerase III [Bacillus cereus].	34.60	656	376	22	3	627	5	638	5e-88	302
tr:U2JF73_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERJ78677.1};	32.64	622	374	14	1	592	17	623	5e-88	300
rs:WP_009229076	DNA topoisomerase III [Prevotella sp. oral taxon 299].	32.12	688	405	17	1	638	1	676	5e-88	301
rs:WP_010990062	DNA topoisomerase III [Listeria monocytogenes].	33.03	651	379	18	3	627	5	624	5e-88	302
rs:WP_013274289	DNA topoisomerase III [[Clostridium] saccharolyticum].	31.26	691	400	24	1	654	1	653	5e-88	301
rs:WP_014093960	DNA topoisomerase III [Listeria ivanovii].	32.82	652	379	19	3	627	5	624	5e-88	302
tr:F9D0D7_PREDD	SubName: Full=DNA topoisomerase TopB {ECO:0000313|EMBL:EGQ16953.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EGQ16953.1};	30.66	698	403	19	1	630	36	720	5e-88	302
rs:WP_004081462	DNA topoisomerase III [Clostridium sp. ASF502].	31.29	703	423	21	2	673	5	678	5e-88	301
rs:WP_044201455	DNA topoisomerase III [Flammeovirga sp. OC4].	31.16	735	431	23	1	687	1	708	5e-88	304
rs:WP_044349470	DNA topoisomerase III [Raoultella ornithinolytica].	33.17	627	377	19	1	597	1	615	6e-88	300
rs:WP_024992172	DNA topoisomerase III [Prevotella pleuritidis].	30.71	687	406	17	1	630	1	674	6e-88	301
rs:WP_000047303	DNA topoisomerase III [Bacillus cereus].	34.60	656	376	22	3	627	5	638	6e-88	302
rs:WP_015584599	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	33.55	611	367	18	1	581	1	602	6e-88	300
rs:WP_014602293	DNA topoisomerase III [Listeria monocytogenes].	32.98	652	378	18	3	627	5	624	6e-88	302
rs:WP_022620845	DNA topoisomerase type IA Tn1549-like CTn5-Orf16 [Peptoclostridium difficile].	34.67	600	347	15	1	587	1	568	6e-88	298
rs:WP_000047307	DNA topoisomerase III [Bacillus cereus].	34.60	656	376	22	3	627	5	638	6e-88	302
rs:WP_000047304	DNA topoisomerase III [Bacillus cereus].	34.60	656	376	22	3	627	5	638	6e-88	302
rs:WP_008147589	DNA topoisomerase III [Parabacteroides johnsonii].	30.34	702	426	16	1	653	1	688	6e-88	301
rs:WP_007760307	DNA topoisomerase III [Cronobacter turicensis].	31.77	661	388	23	1	622	1	637	6e-88	300
rs:WP_045844069	DNA topoisomerase III [Yersinia ruckeri].	33.12	619	359	19	1	581	1	602	6e-88	300
rs:WP_002838913	DNA topoisomerase III [Finegoldia magna].	34.35	591	345	13	1	579	1	560	6e-88	298
rs:WP_001140211	DNA topoisomerase III [Bacillus cereus].	34.29	659	374	22	3	627	5	638	6e-88	302
rs:WP_021639605	DNA topoisomerase [Clostridium sp. KLE 1755].	30.32	709	434	20	1	680	1	678	7e-88	301
rs:WP_000047305	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	34.60	656	376	22	3	627	5	638	7e-88	302
rs:WP_033920949	DNA topoisomerase III [Listeria monocytogenes].	33.03	651	379	18	3	627	5	624	7e-88	302
rs:WP_044942700	DNA topoisomerase III [Blautia schinkii].	30.24	701	428	17	2	671	4	674	7e-88	301
rs:WP_041073026	DNA topoisomerase III [Bacillus sp. OxB-1].	33.54	653	382	22	3	627	5	633	7e-88	302
rs:WP_000047306	DNA topoisomerase III [Bacillus cereus].	34.60	656	376	22	3	627	5	638	7e-88	302
rs:WP_025838455	DNA topoisomerase III [Porphyromonas cangingivalis].	31.31	674	408	20	1	636	1	657	7e-88	300
rs:WP_002115767	DNA topoisomerase III [Bacillus cereus].	34.45	656	377	22	3	627	5	638	7e-88	302
rs:WP_016097322	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	31.58	722	434	22	3	682	4	707	7e-88	301
rs:WP_009924395	DNA topoisomerase III [Listeria monocytogenes].	32.98	652	378	18	3	627	5	624	7e-88	302
rs:WP_014118863	DNA topoisomerase III [Oscillibacter valericigenes].	30.94	711	431	22	1	687	1	675	7e-88	301
rs:WP_003722116	DNA topoisomerase III [Listeria monocytogenes].	32.98	652	378	18	3	627	5	624	7e-88	302
rs:WP_013671195	DNA topoisomerase III [Prevotella denticola].	32.34	603	367	13	1	574	1	591	7e-88	299
rs:WP_039175406	DNA topoisomerase III [Listeria monocytogenes].	32.98	652	378	18	3	627	5	624	7e-88	301
rs:WP_021589015	DNA topoisomerase III [Prevotella baroniae].	32.23	605	374	12	1	581	1	593	7e-88	299
rs:WP_015740971	DNA topoisomerase III [Cronobacter turicensis].	31.77	661	388	23	1	622	1	637	7e-88	300
rs:WP_021315120	DNA topoisomerase III [Dehalobacter sp. UNSWDHB].	30.70	710	435	19	1	683	1	680	8e-88	301
rs:WP_003740322	DNA topoisomerase III [Listeria monocytogenes].	33.03	651	379	18	3	627	5	624	8e-88	301
tr:D5Q4K0_PEPDI	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFH07133.1};	32.43	703	409	20	1	671	4	672	8e-88	301
tr:F0V072_SALBN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.83	637	412	13	1	615	1	624	8e-88	300
rs:WP_010789663	IncP-type DNA topoisomerase III TraE [Bacillus atrophaeus].	32.78	659	390	20	3	631	5	640	8e-88	302
rs:WP_044624791	DNA topoisomerase III [Tamlana nanhaiensis].	30.94	724	412	23	1	675	1	685	8e-88	303
rs:WP_000047310	DNA topoisomerase III [Bacillus cereus].	34.60	656	376	22	3	627	5	638	8e-88	302
rs:WP_004121401	MULTISPECIES: DNA topoisomerase III [Klebsiella].	32.58	663	398	21	1	632	1	645	8e-88	300
tr:L1NI24_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	33.28	616	378	15	1	598	23	623	8e-88	301
rs:WP_035241401	DNA topoisomerase III [Desulfobacter vibrioformis].	31.25	704	427	15	1	671	1	680	8e-88	301
rs:WP_036851418	DNA topoisomerase III [Porphyromonas cangingivalis].	31.31	674	408	20	1	636	1	657	8e-88	300
rs:WP_015059025	hypothetical protein [Escherichia coli].	32.13	666	405	15	1	629	1	656	8e-88	300
rs:WP_001094104	DNA topoisomerase III [Bacillus cereus].	31.40	723	430	22	3	680	4	705	9e-88	301
rs:WP_004860845	DNA topoisomerase III [Klebsiella oxytoca].	33.55	611	367	18	1	581	1	602	9e-88	300
rs:WP_026901741	DNA topoisomerase III [Peptostreptococcaceae bacterium VA2].	33.94	660	360	26	3	631	5	619	9e-88	301
rs:WP_038180256	DNA topoisomerase III [Viridibacillus arenosi].	33.59	643	369	17	3	615	5	619	9e-88	302
rs:WP_008565033	DNA topoisomerase III [Prevotella maculosa].	30.74	706	400	19	1	629	1	694	9e-88	301
rs:WP_038863407	DNA topoisomerase III [Cronobacter muytjensii].	32.15	619	365	20	1	581	1	602	9e-88	300
rs:WP_046958857	DNA topoisomerase III [Bacillus cereus].	33.99	659	376	22	3	627	5	638	9e-88	302
rs:WP_012951084	DNA topoisomerase III [Listeria monocytogenes].	32.98	652	378	18	3	627	5	624	9e-88	301
rs:WP_045121307	hypothetical protein, partial [Haliangium ochraceum].	29.95	738	441	19	3	680	6	727	1e-87	304
rs:WP_021583388	DNA topoisomerase III [Prevotella pleuritidis].	30.47	686	409	15	1	630	1	674	1e-87	301
rs:WP_004381796	DNA topoisomerase III [Prevotella veroralis].	32.79	619	365	15	1	581	1	606	1e-87	299
tr:A0A078M9U1_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.44	655	385	20	2	627	4	636	1e-87	301
tr:A0A0C5PJ08_ECOLX	SubName: Full=Isolate FP671 plasmid pHNFP671, complete sequence {ECO:0000313|EMBL:AJQ17236.1};	32.13	666	405	15	1	629	1	656	1e-87	300
rs:WP_044790817	DNA topoisomerase III [Bacillus thuringiensis].	34.14	659	375	22	3	627	5	638	1e-87	301
rs:WP_021773317	DNA topoisomerase [Oribacterium sp. oral taxon 078].	30.57	700	431	20	1	673	1	672	1e-87	301
rs:WP_007678182	DNA topoisomerase III [Cronobacter condimenti].	31.29	620	369	19	1	581	1	602	1e-87	300
rs:WP_001140212	DNA topoisomerase III [Bacillus cereus].	34.19	661	372	23	3	627	5	638	1e-87	301
tr:D0LL88_HALO1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.95	738	441	19	3	680	6	727	1e-87	305
rs:WP_035407321	DNA topoisomerase III [Bacillus sp. SJS].	33.59	652	388	20	3	630	5	635	1e-87	301
rs:WP_038408056	DNA topoisomerase III [Listeria ivanovii].	32.82	652	379	19	3	627	5	624	1e-87	301
rs:WP_036878228	DNA topoisomerase III [Prevotella oryzae].	32.12	688	385	24	1	629	1	665	1e-87	300
rs:WP_038857389	DNA topoisomerase III [Cronobacter universalis].	31.77	661	388	23	1	622	1	637	1e-87	299
rs:WP_044220056	DNA topoisomerase III [Flammeovirga pacifica].	30.79	721	430	20	1	676	1	697	1e-87	303
tr:M1P191_DESSD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.57	643	395	17	32	652	15	634	1e-87	300
rs:WP_045816928	DNA topoisomerase III [Pantoea sp. SM3].	29.98	637	406	14	1	611	1	623	1e-87	300
rs:WP_038188930	DNA topoisomerase III [Xenorhabdus bovienii].	33.61	610	368	16	1	581	1	602	1e-87	299
rs:WP_027951620	DNA topoisomerase III [Hallella seregens].	30.52	698	404	19	1	630	1	685	1e-87	300
rs:WP_039352756	DNA topoisomerase III [Chryseobacterium jeonii].	31.98	713	428	23	1	675	1	694	1e-87	301
rs:WP_003739949	DNA topoisomerase III [Listeria monocytogenes].	33.03	651	379	18	3	627	5	624	1e-87	301
rs:WP_038409316	DNA topoisomerase III [Listeria ivanovii].	32.82	652	379	19	3	627	5	624	1e-87	301
rs:WP_011146773	DNA topoisomerase III [Photorhabdus luminescens].	33.66	618	357	20	1	581	1	602	1e-87	299
rs:WP_016778794	DNA topoisomerase III [Anaerophaga thermohalophila].	30.70	710	447	17	1	678	1	697	1e-87	303
rs:WP_012064441	DNA topoisomerase III [Alkaliphilus metalliredigens].	32.88	669	405	19	2	644	4	654	1e-87	301
sp:TOP3_BACLD	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	33.85	650	387	19	3	627	5	636	1e-87	301
rs:WP_023363291	DNA topoisomerase III [Escherichia coli].	32.28	666	404	15	1	629	1	656	2e-87	300
rs:WP_000047313	DNA topoisomerase III [Bacillus thuringiensis].	34.14	659	375	22	3	627	5	638	2e-87	301
rs:WP_009587401	DNA topoisomerase III [Clostridium sp. HGF2].	31.91	633	392	14	3	615	5	618	2e-87	301
rs:WP_024300313	DNA topoisomerase [Methylosarcina lacus].	30.28	654	424	11	1	643	1	633	2e-87	300
rs:WP_034283847	DNA topoisomerase III [Bacillus safensis].	32.72	648	397	17	3	627	5	636	2e-87	301
rs:WP_004072223	DNA topoisomerase III [Desulfobacter postgatei].	31.78	686	413	16	1	654	1	663	2e-87	301
rs:WP_008824610	DNA topoisomerase III [Haloplasma contractile].	33.89	655	392	17	3	629	5	646	2e-87	301
rs:WP_034720218	DNA topoisomerase III [Chryseobacterium antarcticum].	32.02	709	433	21	1	675	1	694	2e-87	300
rs:WP_008817173	DNA topoisomerase III [Peptoclostridium difficile].	31.91	633	392	14	3	615	5	618	2e-87	301
rs:WP_035703807	DNA topoisomerase III [Bacillus altitudinis].	33.13	649	393	19	3	627	5	636	2e-87	301
rs:WP_012988871	DNA topoisomerase III [Xenorhabdus bovienii].	33.77	610	367	17	1	581	1	602	2e-87	299
rs:WP_025206777	DNA topoisomerase III [Bacillus pumilus].	33.02	648	395	18	3	627	5	636	2e-87	301
tr:E5B623_ERWAM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.39	620	356	21	1	581	1	602	2e-87	299
rs:WP_045689151	DNA topoisomerase III [Hymenobacter sp. AT01-02].	27.94	741	459	15	1	675	1	732	2e-87	303
rs:WP_018910169	DNA topoisomerase III [Prevotella veroralis].	32.63	619	366	15	1	581	1	606	2e-87	298
rs:WP_000047308	DNA topoisomerase III [Bacillus cereus].	34.60	656	376	22	3	627	5	638	2e-87	301
rs:WP_025093607	DNA topoisomerase III [Bacillus pumilus].	32.72	648	397	17	3	627	5	636	2e-87	301
rs:WP_036780803	DNA topoisomerase III [Photorhabdus luminescens].	33.44	616	361	19	1	581	1	602	2e-87	299
rs:WP_005794610	DNA topoisomerase I [Bacteroides fragilis].	31.81	701	429	21	1	676	1	677	2e-87	300
gp:CP000002_471	DNA topoisomerase III [Bacillus licheniformis DSM 13 = ATCC 14580]	33.85	650	387	19	3	627	7	638	2e-87	301
rs:WP_016885166	DNA topoisomerase III [Bacillus licheniformis].	33.85	650	387	19	3	627	16	647	2e-87	301
rs:WP_004169946	DNA topoisomerase III [Erwinia amylovora].	33.39	620	356	21	1	581	1	602	2e-87	299
rs:WP_042103769	DNA topoisomerase III [Escherichia coli].	29.22	664	426	17	1	633	1	651	2e-87	299
rs:WP_034777902	DNA topoisomerase III [Exiguobacterium mexicanum].	30.80	685	434	16	1	653	1	677	2e-87	300
rs:WP_004892848	DNA topoisomerase III [Klebsiella pneumoniae].	33.39	614	364	20	1	581	1	602	2e-87	299
rs:WP_001140210	DNA topoisomerase 3 [Bacillus thuringiensis].	34.14	659	375	22	3	627	5	638	2e-87	301
rs:WP_003179052	DNA topoisomerase III [Bacillus licheniformis].	33.85	650	387	19	3	627	16	647	2e-87	301
rs:WP_001750506	DNA topoisomerase III [Salmonella enterica].	31.33	616	379	15	1	581	1	607	2e-87	300
rs:WP_000241071	DNA topoisomerase III [Bacillus cereus].	33.94	654	383	21	3	627	5	638	2e-87	301
gp:AE017333_478	DNA topoisomerase III [Bacillus licheniformis DSM 13 = ATCC 14580]	33.85	650	387	19	3	627	8	639	2e-87	301
rs:WP_045958510	DNA topoisomerase III [Xenorhabdus poinarii].	33.01	615	365	16	1	581	1	602	2e-87	299
rs:WP_000047321	DNA topoisomerase III [Bacillus cereus].	34.30	656	378	22	3	627	5	638	2e-87	301
rs:WP_023548258	DNA topoisomerase III [Listeria monocytogenes].	33.03	651	379	18	3	627	5	624	2e-87	300
rs:WP_003510888	DNA topoisomerase III [[Clostridium] symbiosum].	30.65	708	440	20	1	683	1	682	2e-87	300
rs:WP_033918257	DNA topoisomerase III [Listeria monocytogenes].	32.98	652	378	18	3	627	5	624	2e-87	300
rs:WP_011877338	DNA topoisomerase III [Desulfotomaculum reducens].	30.87	716	435	19	3	682	4	695	2e-87	302
sp:TOP3_BACC1	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	34.14	659	375	22	3	627	5	638	2e-87	301
rs:WP_004362216	DNA topoisomerase III [Prevotella nigrescens].	33.06	608	365	13	1	578	1	596	2e-87	298
rs:WP_000047320	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	34.45	656	377	22	3	627	5	638	2e-87	301
rs:WP_017762755	DNA topoisomerase III [Bacillus thuringiensis].	34.45	656	377	22	3	627	5	638	2e-87	301
rs:WP_036805538	DNA topoisomerase III [Photorhabdus luminescens].	33.44	616	361	19	1	581	1	602	2e-87	298
rs:WP_005834124	DNA topoisomerase I [Bacteroides uniformis].	31.09	714	436	19	1	683	1	689	2e-87	300
rs:WP_006044967	DNA topoisomerase III [Prevotella pallens].	33.17	621	371	15	1	590	1	608	2e-87	298
rs:WP_042524880	DNA topoisomerase III [Yersinia ruckeri].	33.12	619	359	19	1	581	1	602	2e-87	298
rs:WP_000047265	DNA topoisomerase III [Bacillus cereus].	33.99	659	376	22	3	627	5	638	3e-87	301
rs:WP_041106477	DNA topoisomerase III [Bacillus pumilus].	32.56	648	398	17	3	627	5	636	3e-87	300
rs:WP_019167893	DNA topoisomerase III [Staphylococcus intermedius].	32.80	628	384	16	3	615	5	609	3e-87	300
rs:WP_046324898	DNA topoisomerase III [Listeria seeligeri].	32.98	652	378	19	3	627	5	624	3e-87	300
rs:WP_019967377	DNA topoisomerase III [Prevotella maculosa].	31.50	708	392	22	1	629	1	694	3e-87	300
rs:WP_002609188	DNA topoisomerase III [[Clostridium] innocuum].	31.75	633	393	14	3	615	5	618	3e-87	300
rs:WP_034622892	DNA topoisomerase III [Bacillus safensis].	32.56	648	398	17	3	627	5	636	3e-87	300
rs:WP_019034962	DNA topoisomerase III [Peptoniphilus lacrimalis].	34.52	591	344	14	1	579	1	560	3e-87	296
rs:WP_018361859	DNA topoisomerase III [Prevotella nanceiensis].	32.21	683	401	17	1	633	1	671	3e-87	299
rs:WP_038336868	DNA topoisomerase III [Empedobacter falsenii].	31.54	726	414	25	1	671	1	698	3e-87	300
rs:WP_016716345	DNA topoisomerase 3 [Bacillus cereus].	34.14	659	375	22	3	627	5	638	3e-87	300
rs:WP_000047289	DNA topoisomerase III [Bacillus cereus].	33.84	659	377	22	3	627	5	638	3e-87	300
rs:WP_017366641	DNA topoisomerase III [Bacillus pumilus].	33.13	649	393	19	3	627	5	636	3e-87	300
rs:WP_033193536	DNA topoisomerase III, partial [Amphibacillus jilinensis].	32.14	644	398	18	3	627	5	628	3e-87	300
rs:WP_035385321	DNA topoisomerase III, partial [Ferrimonas futtsuensis].	31.25	608	386	11	1	581	1	603	3e-87	298
rs:WP_040226472	DNA topoisomerase III [Klebsiella pneumoniae].	33.28	619	358	22	1	581	1	602	3e-87	298
rs:WP_016106882	DNA topoisomerase III [Bacillus cereus].	31.30	722	436	21	3	682	4	707	3e-87	300
rs:WP_007885442	DNA topoisomerase III [Pantoea sp. GM01].	30.63	640	402	15	1	613	1	625	3e-87	299
rs:WP_002506961	DNA topoisomerase III [Staphylococcus sp. OJ82].	34.29	630	373	15	3	615	4	609	3e-87	300
tr:C2YLG1_BACCE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	34.30	656	378	22	3	627	9	642	3e-87	300
rs:WP_031644012	DNA topoisomerase III [Listeria monocytogenes].	33.03	651	379	18	3	627	5	624	3e-87	300
rs:WP_001682052	DNA topoisomerase III [Escherichia coli].	29.22	640	414	14	1	614	1	627	3e-87	299
rs:WP_022300665	DNA topoisomerase [Erysipelotrichaceae bacterium CAG:64].	31.75	633	393	14	3	615	5	618	3e-87	300
rs:WP_008727758	DNA topoisomerase III [Erysipelotrichaceae bacterium 2_2_44A].	31.75	633	393	14	3	615	5	618	3e-87	300
rs:WP_000047323	DNA topoisomerase III [Bacillus cereus].	34.14	659	375	22	3	627	5	638	3e-87	300
rs:WP_000047318	DNA topoisomerase III [Bacillus cereus].	34.45	656	377	22	3	627	5	638	3e-87	300
rs:WP_039963133	DNA topoisomerase III [Bacillus stratosphericus].	33.13	649	393	19	3	627	5	636	3e-87	300
rs:WP_000047312	DNA topoisomerase III [Bacillus cereus].	34.14	659	375	22	3	627	5	638	3e-87	300
rs:WP_010529471	DNA topoisomerase III [Lentibacillus jeotgali].	32.01	706	446	14	4	681	5	704	3e-87	300
rs:WP_032414799	DNA topoisomerase III [Klebsiella pneumoniae].	33.12	619	359	22	1	581	1	602	3e-87	298
rs:WP_009330155	MULTISPECIES: DNA topoisomerase III [Bacillus].	33.85	650	387	19	3	627	16	647	3e-87	300
rs:WP_009270778	DNA topoisomerase III [Erysipelotrichaceae bacterium 21_3].	32.19	702	418	18	3	673	5	679	3e-87	300
rs:WP_033958343	DNA topoisomerase III [Psychroserpens sp. PAMC 27130].	32.96	719	416	23	1	680	1	692	3e-87	301
rs:WP_044907297	DNA topoisomerase III [[Clostridium] innocuum].	31.75	633	393	14	3	615	5	618	3e-87	300
rs:WP_008466850	DNA topoisomerase III [Pseudoalteromonas sp. BSi20439].	32.80	628	375	14	1	596	1	613	3e-87	298
rs:WP_025839347	DNA topoisomerase III [Prevotella scopos].	32.22	630	368	14	1	591	1	610	3e-87	297
rs:WP_007172766	DNA topoisomerase III [Prevotella bergensis].	30.64	692	406	17	1	630	1	680	3e-87	299
rs:WP_009905839	DNA topoisomerase III [Peptoclostridium difficile].	33.59	655	369	23	3	631	5	619	3e-87	299
rs:WP_025277526	DNA topoisomerase III [Barnesiella viscericola].	33.72	599	357	15	1	581	1	577	4e-87	300
rs:WP_029441506	DNA topoisomerase III [Bacillus thuringiensis].	34.45	656	377	22	3	627	5	638	4e-87	300
rs:WP_044564917	DNA topoisomerase [Anaerococcus sp. 9402080].	34.80	592	341	15	1	579	1	560	4e-87	296
rs:WP_001129910	DNA topoisomerase III [Bacillus cereus].	34.30	656	378	22	3	627	5	638	4e-87	300
rs:WP_041116726	DNA topoisomerase III [Bacillus pumilus].	32.56	648	398	17	3	627	5	636	4e-87	300
rs:WP_001140203	DNA topoisomerase III [Bacillus cereus].	34.14	659	375	22	3	627	5	638	4e-87	300
rs:WP_014710026	DNA topoisomerase III [Prevotella intermedia].	32.58	620	376	13	1	590	1	608	4e-87	297
rs:WP_024153970	DNA topoisomerase III [Salmonella enterica].	29.49	641	405	14	1	613	1	622	4e-87	299
rs:WP_013264979	DNA topoisomerase III [Prevotella melaninogenica].	32.15	622	379	13	1	591	1	610	4e-87	297
rs:WP_024153900	DNA topoisomerase III [Salmonella enterica].	30.21	609	385	13	1	581	1	597	4e-87	299
rs:WP_047100582	DNA topoisomerase III [Dickeya dianthicola].	30.47	640	404	14	1	614	1	625	4e-87	298
rs:WP_031644988	DNA topoisomerase III [Listeria monocytogenes].	32.82	652	379	18	3	627	5	624	4e-87	300
rs:WP_004430385	MULTISPECIES: DNA topoisomerase III [Bacillus subtilis group].	32.63	659	391	20	3	631	5	640	4e-87	300
rs:WP_012986588	DNA topoisomerase III [Listeria seeligeri].	32.82	652	379	19	3	627	5	624	4e-87	300
rs:WP_024427348	DNA topoisomerase III [Bacillus pumilus].	32.56	648	398	17	3	627	5	636	4e-87	300
rs:WP_011703393	DNA topoisomerase III [Listeria welshimeri].	32.82	652	379	18	3	627	5	624	4e-87	300
rs:WP_045131647	DNA topoisomerase III [Listeria monocytogenes].	32.62	653	379	19	3	627	5	624	4e-87	300
gpu:CP011421_1198	DNA topoisomerase III [Klebsiella pneumoniae]	33.17	615	364	21	1	581	1	602	4e-87	298
rs:WP_029566545	DNA topoisomerase III [Bacillus cibi].	32.77	647	396	18	4	627	6	636	4e-87	300
sp:TOP3_BACCZ	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	34.14	659	375	22	3	627	5	638	4e-87	300
rs:WP_000047288	DNA topoisomerase III [Bacillus cereus].	33.84	659	377	22	3	627	5	638	4e-87	300
rs:WP_004196257	DNA topoisomerase III [Klebsiella pneumoniae].	31.98	666	406	15	1	629	1	656	4e-87	298
sp:TOP3_BACAH	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	34.14	659	375	22	3	627	5	638	4e-87	300
rs:WP_009486072	MULTISPECIES: DNA topoisomerase III [Klebsiella].	33.39	614	364	20	1	581	1	602	4e-87	298
rs:WP_001983848	DNA topoisomerase III [Bacillus cereus].	34.14	659	375	22	3	627	5	638	4e-87	300
rs:WP_021094594	MULTISPECIES: DNA topoisomerase III [Anoxybacillus].	30.44	726	453	21	1	687	1	713	4e-87	300
rs:WP_027419728	DNA topoisomerase III [Crocinitomix catalasitica].	32.40	682	417	17	1	655	1	665	4e-87	299
rs:WP_019705495	DNA topoisomerase III [Klebsiella pneumoniae].	33.12	619	359	22	1	581	1	602	4e-87	298
rs:WP_000047311	DNA topoisomerase 3 [Bacillus cereus].	34.14	659	375	22	3	627	5	638	5e-87	300
gpu:CP007685_2786	DNA topoisomerase III [Listeria monocytogenes]	33.03	651	379	18	3	627	5	624	5e-87	300
rs:WP_023283560	DNA topoisomerase III [Klebsiella pneumoniae].	33.33	618	359	21	1	581	1	602	5e-87	298
rs:WP_026977380	DNA topoisomerase III [Flavobacterium tegetincola].	31.80	717	420	23	1	678	1	687	5e-87	301
rs:WP_039073230	DNA topoisomerase III [Bacillus sp. MSP5.4].	33.85	650	387	19	3	627	15	646	5e-87	300
rs:WP_001140202	DNA topoisomerase III [Bacillus cereus].	34.40	654	380	21	3	627	5	638	5e-87	300
rs:WP_007790408	DNA topoisomerase III [Peptostreptococcus stomatis].	35.20	608	341	16	1	595	1	568	5e-87	295
rs:WP_012667948	DNA topoisomerase III [Erwinia pyrifoliae].	33.39	620	356	21	1	581	1	602	5e-87	298
rs:WP_016808486	DNA topoisomerase III [Klebsiella oxytoca].	32.38	667	402	21	1	636	1	649	5e-87	298
rs:WP_004148065	MULTISPECIES: DNA topoisomerase III [Klebsiella].	33.12	619	359	22	1	581	1	602	5e-87	298
rs:WP_004157807	DNA topoisomerase III [Erwinia amylovora].	33.39	620	356	21	1	581	1	602	5e-87	298
rs:WP_040174316	DNA topoisomerase III [Klebsiella pneumoniae].	33.39	614	364	20	1	581	1	602	5e-87	298
rs:WP_032419855	DNA topoisomerase III [Klebsiella pneumoniae].	33.39	614	364	20	1	581	1	602	5e-87	298
rs:WP_038807864	DNA topoisomerase III [Klebsiella pneumoniae].	33.39	614	364	20	1	581	1	602	5e-87	298
rs:WP_010248082	DNA topoisomerase III [Peptoniphilus rhinitidis].	34.63	592	342	15	1	579	1	560	5e-87	295
rs:WP_046199027	DNA topoisomerase III [Bacillus sp. UMTAT18].	34.14	659	375	22	3	627	5	638	5e-87	300
rs:WP_040148465	DNA topoisomerase III [Klebsiella pneumoniae].	33.39	614	364	20	1	581	1	602	5e-87	298
rs:WP_021312943	DNA topoisomerase III [Klebsiella pneumoniae].	33.39	614	364	20	1	581	1	602	5e-87	298
rs:WP_047203830	DNA topoisomerase III [Bacillus pumilus].	33.08	653	388	19	3	627	5	636	5e-87	300
rs:WP_000047309	DNA topoisomerase III [Bacillus thuringiensis].	34.45	656	377	22	3	627	5	638	5e-87	300
rs:WP_042513694	DNA topoisomerase III [Bacillus anthracis].	34.14	659	375	22	3	627	5	638	5e-87	300
rs:WP_003423232	DNA topoisomerase III [Peptoclostridium difficile].	33.59	655	369	23	3	631	5	619	5e-87	299
rs:WP_039345333	DNA topoisomerase III [Chryseobacterium solincola].	32.49	708	432	20	1	677	1	693	5e-87	299
rs:WP_023316738	DNA topoisomerase III [Klebsiella pneumoniae].	33.33	618	359	21	1	581	1	602	5e-87	298
tr:R9M7W1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.10	721	434	24	1	681	1	691	6e-87	299
rs:WP_001990567	DNA topoisomerase 3 [Bacillus cereus].	34.14	659	375	22	3	627	5	638	6e-87	300
rs:WP_042392964	DNA topoisomerase III [Escherichia vulneris].	32.42	623	358	19	1	581	1	602	6e-87	297
rs:WP_021067658	DNA topoisomerase III [Exiguobacterium pavilionensis].	30.95	685	433	16	1	653	1	677	6e-87	299
rs:WP_036611732	DNA topoisomerase III [Oribacterium sp. P6A1].	30.57	723	426	22	1	673	1	697	6e-87	299
rs:WP_001140206	DNA topoisomerase III [Bacillus cereus].	34.19	661	372	23	3	627	5	638	6e-87	300
rs:WP_025568346	DNA topoisomerase III [Bacillus sp. JGI 001005-J19].	34.55	660	367	24	3	627	5	634	6e-87	300
rs:WP_017353184	DNA topoisomerase III [Clostridium botulinum].	33.38	653	388	18	3	627	5	638	6e-87	300
rs:WP_032417775	DNA topoisomerase III [Klebsiella pneumoniae].	33.12	619	359	22	1	581	1	602	6e-87	298
rs:WP_036790296	DNA topoisomerase III [Porphyromonas canoris].	32.06	655	392	21	1	624	1	633	6e-87	298
rs:WP_021912630	DNA topoisomerase [Eubacterium sp. CAG:786].	29.51	698	449	17	1	673	1	680	6e-87	299
rs:WP_032431711	DNA topoisomerase III [Klebsiella pneumoniae].	33.12	619	359	22	1	581	1	602	6e-87	298
rs:WP_023279896	DNA topoisomerase III [Klebsiella pneumoniae].	33.17	615	364	21	1	581	1	602	6e-87	298
rs:WP_017174848	DNA topoisomerase III [Staphylococcus hominis].	33.28	628	381	17	3	615	4	608	6e-87	299
rs:WP_013317851	DNA topoisomerase III [Dickeya dadantii].	31.48	667	391	23	1	627	1	641	6e-87	297
rs:WP_046442595	DNA topoisomerase III [Catabacter hongkongensis].	31.95	698	427	20	1	673	1	675	6e-87	299
rs:WP_041508287	DNA topoisomerase III [Bacillus aerophilus].	32.97	649	394	19	3	627	5	636	6e-87	300
rs:WP_022075325	DNA topoisomerase [Firmicutes bacterium CAG:212].	32.22	658	394	17	3	627	5	643	6e-87	300
rs:WP_046953758	DNA topoisomerase III [Bacillus cereus].	33.84	659	377	22	3	627	5	638	7e-87	300
rs:WP_025799526	DNA topoisomerase III [Prevotella saccharolytica].	32.95	616	380	14	1	598	1	601	7e-87	298
rs:WP_014544395	DNA topoisomerase III [Erwinia sp. Ejp617].	33.39	620	356	21	1	581	1	602	7e-87	297
rs:WP_021167107	DNA topoisomerase 3 [Sporomusa ovata].	32.57	651	395	20	3	627	5	637	7e-87	300
rs:WP_045035034	DNA topoisomerase III [Bacillus invictae].	32.97	649	394	19	3	627	5	636	7e-87	300
rs:WP_042938256	DNA topoisomerase III [Klebsiella pneumoniae].	33.33	618	359	21	1	581	1	602	7e-87	297
rs:WP_029141630	DNA topoisomerase III [Bacillus coagulans].	31.67	663	392	21	3	646	4	624	7e-87	298
rs:WP_004627448	DNA topoisomerase III, bacteria and conjugative plasmid [[Clostridium] termitidis].	32.15	650	399	18	3	627	5	637	7e-87	299
rs:WP_002901390	DNA topoisomerase III [Klebsiella pneumoniae].	33.39	614	364	20	1	581	1	602	7e-87	297
rs:WP_039260585	DNA topoisomerase III [Clostridium tetani].	33.08	656	386	19	3	627	5	638	7e-87	299
rs:WP_038810916	DNA topoisomerase III, partial [Peptoclostridium difficile].	33.64	654	370	21	3	631	5	619	7e-87	299
rs:WP_016090159	DNA topoisomerase III [Bacillus cereus].	31.28	716	440	20	3	680	4	705	7e-87	299
rs:WP_044335056	DNA topoisomerase III [Bacillus safensis].	32.56	648	398	17	3	627	5	636	7e-87	299
rs:WP_024425570	DNA topoisomerase III [Bacillus safensis].	32.56	648	398	17	3	627	5	636	7e-87	299
rs:WP_016085083	DNA topoisomerase III [Bacillus cereus].	31.16	722	437	21	3	682	4	707	7e-87	299
tr:R9TS34_BACLI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.54	653	385	19	3	627	7	638	7e-87	299
rs:WP_026683480	DNA topoisomerase III [Bacillus coagulans].	30.50	659	405	17	3	646	4	624	7e-87	298
rs:WP_027631203	DNA topoisomerase III [[Clostridium] cellobioparum].	32.00	650	400	18	3	627	5	637	7e-87	299
rs:WP_033543275	DNA topoisomerase III [Planococcus sp. CAU13].	33.74	655	375	23	3	627	4	629	8e-87	299
rs:WP_025000225	DNA topoisomerase III [Prevotella aurantiaca].	32.58	620	376	13	1	590	1	608	8e-87	296
rs:WP_038270179	DNA topoisomerase III [Xenorhabdus cabanillasii].	32.85	615	366	16	1	581	1	602	8e-87	297
rs:WP_035065255	DNA topoisomerase III [Anoxybacillus gonensis].	30.27	730	449	19	1	687	1	713	8e-87	299
rs:WP_014601215	DNA topoisomerase III [Listeria monocytogenes].	33.03	651	379	18	3	627	5	624	8e-87	299
rs:WP_036862877	DNA topoisomerase III [Prevotella melaninogenica].	31.99	622	380	13	1	591	1	610	8e-87	296
rs:WP_023285893	hypothetical protein [Klebsiella pneumoniae].	30.31	640	400	16	1	611	1	623	8e-87	298
rs:WP_024109633	MULTISPECIES: DNA topoisomerase III [Dickeya].	30.27	641	404	14	1	614	1	625	8e-87	298
rs:WP_016125362	DNA topoisomerase 3 [Bacillus cereus].	34.30	656	378	22	3	627	5	638	9e-87	299
rs:WP_021671158	DNA topoisomerase III [Prevotella sp. F0091].	32.48	628	369	14	1	591	1	610	9e-87	296
rs:WP_041817152	DNA topoisomerase III [Bacillus licheniformis].	33.54	653	385	19	3	627	15	646	9e-87	299
rs:WP_016195967	DNA topoisomerase III [Arcticibacter svalbardensis].	29.91	702	449	19	1	673	1	688	9e-87	298
rs:WP_004183670	DNA topoisomerase III [Klebsiella pneumoniae].	33.39	614	364	20	1	581	1	602	9e-87	297
rs:WP_000047291	MULTISPECIES: DNA topoisomerase 3 [Bacillus cereus group].	34.30	656	378	22	3	627	5	638	9e-87	299
rs:WP_000047317	DNA topoisomerase III [Bacillus thuringiensis].	33.99	659	376	22	3	627	5	638	9e-87	299
rs:WP_021417641	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.64	654	370	21	3	631	5	619	9e-87	298
rs:WP_000047316	DNA topoisomerase III [Bacillus cereus].	33.99	659	376	22	3	627	5	638	9e-87	299
rs:WP_046397481	DNA topoisomerase III [Photorhabdus luminescens].	33.28	616	362	19	1	581	1	602	9e-87	297
rs:WP_025714542	DNA topoisomerase III [Klebsiella sp. 10982].	33.55	614	363	20	1	581	1	602	1e-86	297
tr:V2N7C2_SALET	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.21	609	385	13	1	581	1	597	1e-86	296
rs:WP_015834119	DNA topoisomerase III [Photorhabdus asymbiotica].	33.39	629	374	21	1	597	1	616	1e-86	297
rs:WP_000047290	DNA topoisomerase III [Bacillus cereus].	34.10	654	382	21	3	627	5	638	1e-86	299
rs:WP_031589874	DNA topoisomerase III [Klebsiella pneumoniae].	33.17	615	364	21	1	581	1	602	1e-86	297
rs:WP_001974718	DNA topoisomerase III [Bacillus cereus].	33.99	659	376	22	3	627	5	638	1e-86	299
rs:WP_023289280	MULTISPECIES: DNA topoisomerase III [Klebsiella].	33.12	619	359	22	1	581	1	602	1e-86	297
rs:WP_013871149	DNA topoisomerase III [Lacinutrix sp. 5H-3-7-4].	30.51	731	408	25	1	676	1	686	1e-86	300
rs:WP_002511446	DNA topoisomerase III [Staphylococcus equorum].	34.13	630	374	15	3	615	4	609	1e-86	298
rs:WP_023282373	DNA topoisomerase III [Klebsiella pneumoniae].	33.39	614	364	20	1	581	1	602	1e-86	297
rs:WP_045333361	DNA topoisomerase III [Enterobacter cloacae].	32.68	612	371	18	1	581	1	602	1e-86	296
rs:WP_008823097	DNA topoisomerase III [Prevotella histicola].	33.23	635	366	17	1	590	1	622	1e-86	296
rs:WP_025670986	DNA topoisomerase III [Bacillus sp. JGI 001011-F15].	34.49	661	366	25	3	627	5	634	1e-86	299
rs:WP_021848434	DNA topoisomerase III [Bacteroides sp. CAG:598].	31.27	646	386	14	1	597	1	637	1e-86	299
rs:WP_032310187	DNA topoisomerase [Escherichia coli].	31.98	666	406	15	1	629	1	656	1e-86	298
rs:WP_024252942	DNA topoisomerase [Escherichia coli].	31.98	666	406	15	1	629	1	656	1e-86	298
rs:WP_032438565	DNA topoisomerase III [Klebsiella pneumoniae].	33.33	618	359	21	1	581	1	602	1e-86	297
sp:TOP3_BACCR	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	34.30	656	378	22	3	627	5	638	1e-86	299
rs:WP_017550807	DNA topoisomerase III [Bacillus coagulans].	30.45	660	404	17	3	646	4	624	1e-86	298
rs:WP_036145124	DNA topoisomerase III [Lysinibacillus sp. BF-4].	33.08	653	390	19	2	627	4	636	1e-86	299
rs:WP_041091165	DNA topoisomerase III [Bacillus pumilus].	32.97	649	394	19	3	627	5	636	1e-86	299
rs:WP_021413935	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.64	654	370	21	3	631	5	619	1e-86	298
rs:WP_037994261	DNA topoisomerase III [Thermoactinomyces sp. Gus2-1].	32.38	627	390	15	3	615	5	611	1e-86	298
rs:WP_026750054	DNA topoisomerase III [Listeria monocytogenes].	32.82	652	379	18	3	627	5	624	1e-86	298
tr:C0QUY8_PERMH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.21	714	411	21	1	683	1	672	1e-86	301
rs:WP_032141116	DNA topoisomerase [Escherichia coli].	31.98	666	406	15	1	629	1	656	1e-86	297
rs:WP_021390633	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.64	654	370	21	3	631	5	619	1e-86	298
rs:WP_037541604	DNA topoisomerase III [Staphylococcus sp. M0480].	33.28	628	381	17	3	615	4	608	1e-86	298
rs:WP_019948955	hypothetical protein [Hymenobacter aerophilus].	28.38	740	454	18	1	673	1	731	1e-86	301
rs:WP_021370480	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.64	654	370	21	3	631	5	619	1e-86	298
rs:WP_038254850	DNA topoisomerase III [Xenorhabdus bovienii].	33.44	610	369	16	1	581	1	602	1e-86	296
rs:WP_035390408	DNA topoisomerase III [Bacillus sp. UNC125MFCrub1.1].	32.97	649	394	19	3	627	5	636	1e-86	299
rs:WP_024720230	DNA topoisomerase III [Bacillus pumilus].	32.97	649	394	19	3	627	5	636	1e-86	299
rs:WP_035185010	DNA topoisomerase III [Bacillus coagulans].	30.45	660	404	17	3	646	4	624	1e-86	298
rs:WP_008357118	DNA topoisomerase III [Bacillus xiamenensis].	32.72	648	397	17	3	627	5	636	1e-86	299
rs:WP_047037701	DNA topoisomerase III [Enterobacter aerogenes].	33.71	614	362	21	1	581	1	602	1e-86	297
rs:WP_022823336	DNA topoisomerase III [Hymenobacter norwichensis].	27.87	750	452	17	1	675	1	736	1e-86	301
rs:WP_021402614	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.64	654	370	21	3	631	5	619	1e-86	298
tr:A0A077UU21_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	34.12	633	369	16	3	615	4	608	1e-86	298
rs:WP_038224744	DNA topoisomerase III [Xenorhabdus bovienii].	33.28	610	370	16	1	581	1	602	1e-86	296
gpu:AP014864_5696	DNA topoisomerase III [Bacillus thuringiensis serovar tolworthi]	34.15	656	379	22	3	627	5	638	1e-86	299
rs:WP_023339139	DNA topoisomerase III [Klebsiella pneumoniae].	33.33	618	359	21	1	581	1	602	1e-86	296
rs:WP_003440272	DNA topoisomerase III [Peptoclostridium difficile].	33.64	654	370	21	3	631	5	619	1e-86	298
tr:C5QM86_9STAP	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.85	627	385	14	3	615	5	609	1e-86	298
rs:WP_047256201	DNA topoisomerase III [Moellerella wisconsensis].	33.72	611	366	17	1	581	1	602	1e-86	296
rs:WP_003465183	DNA topoisomerase III [Gracilibacillus halophilus].	31.57	643	406	17	3	626	5	632	1e-86	298
rs:WP_010966830	DNA topoisomerase III [Clostridium acetobutylicum].	32.42	657	392	19	3	625	5	643	1e-86	298
rs:WP_016078851	DNA topoisomerase III [Bacillus cereus].	30.89	722	439	19	3	682	4	707	1e-86	298
rs:WP_036802988	DNA topoisomerase III [Planomicrobium glaciei].	33.54	650	383	23	3	627	4	629	1e-86	298
rs:WP_038208626	DNA topoisomerase III [Xenorhabdus bovienii].	33.28	610	370	16	1	581	1	602	1e-86	296
rs:WP_023925335	DNA topoisomerase III [Prevotella nigrescens].	32.89	608	366	13	1	578	1	596	1e-86	296
rs:WP_021365580	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.64	654	370	21	3	631	5	619	1e-86	298
rs:WP_036922967	DNA topoisomerase III [Prevotella sp. ICM33].	31.90	630	370	14	1	591	1	610	1e-86	296
rs:WP_038192148	DNA topoisomerase III [Xenorhabdus bovienii].	33.28	610	370	16	1	581	1	602	1e-86	296
rs:WP_000209239	DNA topoisomerase III [Bacillus cereus].	31.30	722	436	21	3	682	4	707	1e-86	298
rs:WP_004112307	DNA topoisomerase III [Klebsiella oxytoca].	32.38	667	402	21	1	636	1	649	1e-86	296
rs:WP_016729072	DNA topoisomerase III [Peptoclostridium difficile].	33.64	654	370	21	3	631	5	619	1e-86	298
rs:WP_014098426	DNA topoisomerase III [Bacillus coagulans].	30.50	659	405	17	3	646	4	624	1e-86	298
rs:WP_032422354	DNA topoisomerase III [Klebsiella pneumoniae].	33.33	618	359	21	1	581	1	602	2e-86	296
rs:WP_036864764	DNA topoisomerase III [Porphyromonas sp. COT-108 OH2963].	32.18	662	395	22	1	630	1	640	2e-86	297
rs:WP_019418265	DNA topoisomerase III [Anoxybacillus kamchatkensis].	30.56	733	443	20	1	687	1	713	2e-86	298
rs:WP_044992660	DNA topoisomerase III [Clostridium sp. ATCC 29733].	30.46	696	435	18	1	670	1	673	2e-86	298
rs:WP_026626030	DNA topoisomerase III [Dysgonomonas capnocytophagoides].	33.39	611	369	14	1	590	1	594	2e-86	297
rs:WP_031943421	conjugal transfer protein TraF [uncultured bacterium].	32.24	670	401	18	1	630	1	657	2e-86	297
rs:WP_037541589	DNA topoisomerase III [Staphylococcus caprae].	32.85	627	385	14	3	615	4	608	2e-86	298
rs:WP_032452512	DNA topoisomerase III [Klebsiella sp. 18A069].	33.33	618	359	21	1	581	1	602	2e-86	296
rs:WP_044784126	DNA topoisomerase III [Bacillus thuringiensis].	34.30	656	378	22	3	627	5	638	2e-86	298
rs:WP_039696268	DNA topoisomerase [Enterobacter cloacae].	31.98	666	406	15	1	629	1	656	2e-86	297
tr:A0A077UKC9_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	34.12	633	369	16	3	615	4	608	2e-86	298
rs:WP_047000850	DNA topoisomerase III [Clostridium beijerinckii].	33.13	652	390	20	3	627	5	637	2e-86	298
rs:WP_042470619	DNA topoisomerase III [Bacillus sp. FF3].	32.73	660	383	22	3	627	5	638	2e-86	298
rs:WP_040654648	DNA topoisomerase III [Oscillibacter sp. 1-3].	29.96	721	435	24	1	681	3	693	2e-86	298
rs:WP_001241570	DNA topoisomerase III [Salmonella enterica].	30.21	609	385	13	1	581	1	597	2e-86	297
rs:WP_046342695	DNA topoisomerase III [Bacillus pumilus].	32.97	649	394	19	3	627	5	636	2e-86	298
rs:WP_046179383	DNA topoisomerase III [Domibacillus sp. PAMC 80007].	34.09	657	378	23	3	627	5	638	2e-86	298
rs:WP_036847223	DNA topoisomerase III [Porphyromonas sp. COT-108 OH1349].	32.02	662	396	22	1	630	1	640	2e-86	297
rs:WP_009257933	DNA topoisomerase III [Lachnospiraceae bacterium 7_1_58FAA].	29.12	704	444	19	1	679	1	674	2e-86	297
rs:WP_022618510	DNA topoisomerase III [Peptoclostridium difficile].	33.64	654	370	21	3	631	5	619	2e-86	298
rs:WP_012441306	DNA topoisomerase III [Erwinia tasmaniensis].	32.79	619	361	20	1	581	1	602	2e-86	296
rs:WP_045657767	DNA topoisomerase III [Clostridiaceae bacterium BRH_c20a].	33.38	656	385	19	2	626	4	638	2e-86	298
rs:WP_001140207	DNA topoisomerase III [Bacillus anthracis].	33.99	659	376	22	3	627	5	638	2e-86	298
rs:WP_000241072	DNA topoisomerase III [Bacillus cereus].	34.30	656	378	22	3	627	5	638	2e-86	298
rs:WP_004361160	DNA topoisomerase III [Prevotella melaninogenica].	32.06	630	369	14	1	591	1	610	2e-86	295
rs:WP_021338404	DNA topoisomerase III [Staphylococcus equorum].	34.13	630	374	15	3	615	4	609	2e-86	298
rs:WP_034767491	DNA topoisomerase III [Bacillus thermoamylovorans].	31.39	618	384	12	3	611	4	590	2e-86	298
tr:W7RM55_BACLI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.69	650	388	19	3	627	5	636	2e-86	298
rs:WP_021366949	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.64	654	370	21	3	631	5	619	2e-86	298
rs:WP_022827355	DNA topoisomerase III [Flavobacterium antarcticum].	31.76	721	415	24	1	678	1	687	2e-86	299
rs:WP_021377959	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.64	654	370	21	3	631	5	619	2e-86	298
rs:WP_000047292	DNA topoisomerase III [Bacillus cereus].	34.30	656	378	22	3	627	5	638	2e-86	298
rs:WP_042147566	DNA topoisomerase III [Pseudoalteromonas sp. '520P1 No. 412'].	32.48	628	371	15	1	590	1	613	2e-86	296
rs:WP_012423320	DNA topoisomerase III [Clostridium botulinum].	33.08	653	390	18	3	627	5	638	2e-86	298
rs:WP_046618303	DNA topoisomerase III [Enterobacter cloacae].	32.68	612	371	18	1	581	1	602	2e-86	296
tr:A0A077W394_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.97	633	370	16	3	615	4	608	2e-86	298
rs:WP_044397968	DNA topoisomerase III [Lacinutrix sp. Hel_I_90].	30.45	716	428	22	1	676	1	686	2e-86	299
rs:WP_000047284	DNA topoisomerase III [Bacillus cereus].	33.99	659	376	22	3	627	5	638	2e-86	298
rs:WP_008347145	MULTISPECIES: DNA topoisomerase III [Bacillus].	32.97	649	394	19	3	627	5	636	2e-86	298
rs:WP_021394124	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.64	654	370	21	3	631	5	619	2e-86	298
rs:WP_045923569	DNA topoisomerase III [Clostridium tetani].	32.93	656	387	19	3	627	5	638	2e-86	298
tr:U2EZI4_CLOS4	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.42	697	436	18	1	671	3	676	2e-86	297
rs:WP_023302569	DNA topoisomerase III [Klebsiella pneumoniae].	32.85	618	362	20	1	581	1	602	2e-86	296
rs:WP_047054042	DNA topoisomerase III [Enterobacter aerogenes].	33.55	614	363	21	1	581	1	602	2e-86	296
rs:WP_045269436	DNA topoisomerase III [Enterobacter sp. 35730].	31.86	609	380	15	1	581	1	602	2e-86	296
rs:WP_044996218	DNA topoisomerase III [Lachnospiraceae bacterium JC7].	30.15	713	432	21	2	673	4	691	2e-86	298
rs:WP_038218184	DNA topoisomerase III [Xenorhabdus bovienii].	33.28	610	370	16	1	581	1	602	2e-86	296
rs:WP_000209235	DNA topoisomerase III [Bacillus cereus].	31.72	722	433	22	3	682	4	707	2e-86	298
rs:WP_034947635	DNA topoisomerase III [Erwinia oleae].	29.81	681	429	21	1	647	1	666	2e-86	296
rs:WP_029437302	DNA topoisomerase III [Bacillus thuringiensis].	34.30	656	378	22	3	627	5	638	2e-86	298
rs:WP_046147493	DNA topoisomerase III [Parabacteroides goldsteinii].	29.99	697	427	16	1	650	1	683	2e-86	297
rs:WP_023437240	DNA topoisomerase III [Clostridium tetani].	32.93	656	387	19	3	627	6	639	2e-86	298
rs:WP_014186245	DNA topoisomerase III [Desulfosporosinus orientis].	32.42	657	389	19	3	627	5	638	2e-86	298
rs:WP_047027173	DNA topoisomerase III [Enterobacter sp. GN02186].	31.05	641	407	15	1	613	1	634	2e-86	296
rs:WP_025710032	DNA topoisomerase III [Bacillus subtilis].	34.15	656	379	22	3	627	5	638	2e-86	298
rs:WP_009362688	DNA topoisomerase III [Anoxybacillus sp. DT3-1].	30.52	724	455	19	1	687	1	713	2e-86	298
rs:WP_022021451	DNA topoisomerase III [Bacteroides sp. CAG:661].	30.87	690	407	17	1	641	1	669	2e-86	298
rs:WP_009838492	DNA topoisomerase III [Pseudoalteromonas tunicata].	33.50	612	365	14	1	581	1	601	2e-86	295
rs:WP_031516833	DNA topoisomerase III [Desulfotomaculum alkaliphilum].	31.51	714	433	21	3	680	4	697	2e-86	300
rs:WP_000047283	DNA topoisomerase III [Bacillus cereus].	33.99	659	376	22	3	627	5	638	2e-86	298
rs:WP_021359429	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.64	654	370	21	3	631	5	619	2e-86	297
rs:WP_007658541	DNA topoisomerase III [Parabacteroides goldsteinii].	29.99	697	427	16	1	650	1	683	3e-86	297
rs:WP_014262670	MULTISPECIES: DNA topoisomerase III [Firmicutes].	34.79	595	339	14	1	580	1	561	3e-86	294
rs:WP_043926749	DNA topoisomerase III [Bacillus licheniformis].	33.69	650	388	19	3	627	15	646	3e-86	298
tr:A0A077UAU7_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.97	633	370	16	3	615	4	608	3e-86	297
rs:WP_045855018	DNA topoisomerase III [Raoultella terrigena].	31.52	663	404	20	1	632	1	644	3e-86	296
rs:WP_004366086	DNA topoisomerase III [Prevotella nigrescens].	32.42	620	377	13	1	590	1	608	3e-86	295
rs:WP_033155036	MULTISPECIES: DNA topoisomerase III [Bacillus].	33.69	650	388	19	3	627	15	646	3e-86	298
tr:F2B8G7_9NEIS	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.91	634	392	15	1	597	1	625	3e-86	295
rs:WP_047079528	DNA topoisomerase III [Enterobacter aerogenes].	33.55	614	363	21	1	581	1	602	3e-86	296
rs:WP_047354069	DNA topoisomerase III [Enterobacter sp. GN02315].	32.32	628	381	19	1	597	1	615	3e-86	295
rs:WP_022101784	DNA topoisomerase III [Prevotella sp. CAG:5226].	29.66	708	409	17	1	629	1	698	3e-86	297
rs:WP_008679336	DNA topoisomerase III [Clostridium sp. 7_2_43FAA].	33.54	647	394	18	3	627	5	637	3e-86	298
rs:WP_010802584	MULTISPECIES: DNA topoisomerase III [Parabacteroides].	29.99	697	427	16	1	650	1	683	3e-86	297
rs:WP_047036902	DNA topoisomerase III [Enterobacter aerogenes].	33.33	615	363	22	1	581	1	602	3e-86	296
rs:WP_043937735	MULTISPECIES: DNA topoisomerase III [Bacillus].	34.30	656	378	22	3	627	5	638	3e-86	298
rs:WP_023581968	DNA topoisomerase III [Proteus hauseri].	33.99	612	363	17	1	581	1	602	3e-86	296
rs:WP_040649807	DNA topoisomerase III [Ruminococcaceae bacterium D16].	29.57	700	446	19	1	679	1	674	3e-86	297
rs:WP_035637696	DNA topoisomerase III [Lachnospiraceae bacterium ND2006].	30.58	726	430	22	1	683	1	695	3e-86	297
rs:WP_013366590	DNA topoisomerase III [Enterobacter lignolyticus].	33.11	607	361	20	1	574	1	595	3e-86	295
rs:WP_022543364	DNA topoisomerase III [Bacillus infantis].	31.68	666	390	20	3	646	4	626	3e-86	297
rs:WP_021360748	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.94	654	368	21	3	631	5	619	3e-86	297
rs:WP_021544269	hypothetical protein [Escherichia coli].	29.33	641	413	15	1	614	1	628	3e-86	296
rs:WP_017110286	DNA topoisomerase III [Vibrio tasmaniensis].	29.97	704	434	20	1	669	1	680	3e-86	297
rs:WP_003019763	MULTISPECIES: hypothetical protein [Enterobacteriaceae].	31.98	666	406	15	1	629	1	656	3e-86	296
tr:A0A098EJ80_9BACL	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.44	655	377	23	3	627	4	629	3e-86	297
rs:WP_032714745	DNA topoisomerase III [Enterobacter aerogenes].	33.55	614	363	21	1	581	1	602	3e-86	296
rs:WP_015705779	DNA topoisomerase III [Enterobacter aerogenes].	33.55	614	363	21	1	581	1	602	3e-86	296
rs:WP_000047294	DNA topoisomerase 3 [Bacillus cereus].	34.15	656	379	22	3	627	5	638	3e-86	298
rs:WP_014883454	MULTISPECIES: DNA topoisomerase III [Enterobacter].	31.86	609	380	15	1	581	1	602	3e-86	295
rs:WP_021564887	hypothetical protein [Escherichia coli].	30.18	666	417	20	1	633	1	651	3e-86	296
rs:WP_001140205	DNA topoisomerase III [Bacillus cereus].	33.94	654	383	21	3	627	5	638	3e-86	298
rs:WP_044466810	DNA topoisomerase III [Staphylococcus caprae].	32.70	627	386	14	3	615	4	608	3e-86	297
rs:WP_013859236	DNA topoisomerase III [Bacillus coagulans].	31.67	663	392	21	3	646	4	624	3e-86	297
rs:WP_041954170	DNA topoisomerase [Parvimonas micra].	34.69	591	345	13	1	580	1	561	3e-86	293
rs:WP_034582848	DNA topoisomerase III [Clostridium acetobutylicum].	32.42	657	392	19	3	625	5	643	3e-86	297
tr:A0A077VP33_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.97	633	370	16	3	615	4	608	3e-86	297
rs:WP_041145117	DNA topoisomerase III [Raoultella ornithinolytica].	32.52	612	372	18	1	581	1	602	3e-86	295
rs:WP_042892724	DNA topoisomerase III [Enterobacter aerogenes].	33.55	614	363	21	1	581	1	602	3e-86	295
tr:A0A077V461_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.97	633	370	16	3	615	4	608	3e-86	297
rs:WP_020156037	hypothetical protein [Caldibacillus debilis].	30.69	681	397	20	3	654	4	638	3e-86	296
rs:WP_004368552	DNA topoisomerase III [Prevotella oralis].	32.44	635	377	17	1	608	1	610	3e-86	296
rs:WP_045494938	DNA topoisomerase III [Vibrio sp. 151112A].	30.23	708	431	21	1	669	1	684	3e-86	297
rs:WP_011983474	DNA topoisomerase III [Bacillus cytotoxicus].	33.89	655	382	22	3	627	5	638	4e-86	298
rs:WP_044140538	DNA topoisomerase III [Bacillus pumilus].	33.13	652	389	19	3	627	5	636	4e-86	297
rs:WP_015366158	DNA topoisomerase III [Enterobacter aerogenes].	33.33	615	363	22	1	581	1	602	4e-86	295
rs:WP_016206725	DNA topoisomerase III [Clostridium sartagoforme].	32.98	652	391	20	3	627	5	637	4e-86	298
rs:WP_009904388	DNA topoisomerase III [Peptoclostridium difficile].	33.49	654	371	21	3	631	5	619	4e-86	296
rs:WP_032711859	DNA topoisomerase III [Enterobacter aerogenes].	33.55	614	363	21	1	581	1	602	4e-86	295
rs:WP_019976661	hypothetical protein [Empedobacter brevis].	31.10	717	429	23	1	671	1	698	4e-86	297
rs:WP_032749499	DNA topoisomerase III [Klebsiella oxytoca].	33.06	611	370	18	1	581	1	602	4e-86	295
rs:WP_023984861	DNA topoisomerase III [Prevotella oralis].	32.44	635	377	17	1	608	1	610	4e-86	296
rs:WP_032636920	DNA topoisomerase III [Enterobacter cloacae].	31.86	609	380	15	1	581	1	602	4e-86	295
rs:WP_009890468	DNA topoisomerase III [Peptoclostridium difficile].	33.49	654	371	21	3	631	5	619	4e-86	297
rs:WP_032638381	DNA topoisomerase III [Enterobacter sp. EGD-HP1].	31.86	609	380	15	1	581	1	602	4e-86	295
rs:WP_033695435	DNA topoisomerase III [Bacillus weihenstephanensis].	34.15	656	379	22	3	627	5	638	4e-86	297
rs:WP_047041314	DNA topoisomerase III [Enterobacter aerogenes].	33.55	614	363	21	1	581	1	602	4e-86	295
rs:WP_012582298	DNA topoisomerase III [Listeria monocytogenes].	32.82	652	379	18	3	627	5	624	4e-86	297
rs:WP_028012778	DNA topoisomerase III [Enterobacter cloacae].	31.86	609	380	15	1	581	1	602	4e-86	295
rs:WP_023324481	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	32.52	612	372	18	1	581	1	602	4e-86	295
rs:WP_005825426	DNA topoisomerase I [Bacteroides uniformis].	31.81	701	429	21	1	676	1	677	4e-86	296
rs:WP_044514344	DNA topoisomerase III [Hymenobacter sp. DG25B].	28.28	746	454	20	1	675	1	736	4e-86	300
tr:F4XGQ5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.71	700	445	19	1	679	42	715	4e-86	297
rs:WP_021003063	DNA topoisomerase III [Streptococcus intermedius].	34.29	592	346	14	1	580	1	561	4e-86	293
rs:WP_022650874	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	32.52	612	372	18	1	581	1	602	4e-86	295
rs:WP_006268790	DNA topoisomerase III [Streptococcus constellatus].	34.90	596	337	15	1	580	1	561	4e-86	293
rs:XP_011566445	PREDICTED: DNA topoisomerase 3-like [Plutella xylostella].	31.86	609	380	15	1	581	1	602	4e-86	295
rs:WP_045411298	DNA topoisomerase III [Enterobacter aerogenes].	33.55	614	363	21	1	581	1	602	4e-86	295
rs:WP_032639806	DNA topoisomerase III [Enterobacter cloacae].	31.80	610	379	16	1	581	1	602	4e-86	295
rs:WP_038419141	DNA topoisomerase III [Enterobacter cloacae].	31.86	609	380	15	1	581	1	602	5e-86	295
rs:WP_002842318	DNA topoisomerase [Finegoldia magna].	34.78	575	334	13	1	564	1	545	5e-86	293
rs:WP_020078544	DNA topoisomerase III [Enterobacter aerogenes].	33.55	614	363	21	1	581	1	602	5e-86	295
rs:WP_028059210	DNA topoisomerase III [Solirubrobacter sp. URHD0082].	28.91	709	450	22	3	673	5	697	5e-86	298
rs:WP_021666915	DNA topoisomerase III [Porphyromonas sp. oral taxon 278].	31.01	661	413	21	1	630	1	649	5e-86	296
rs:WP_023520977	DNA topoisomerase III [Bacillus thuringiensis].	33.84	659	377	22	3	627	5	638	5e-86	297
rs:WP_023620725	DNA topoisomerase III [Enterobacter sp. T1-1].	31.86	609	380	15	1	581	1	602	5e-86	295
rs:WP_000047298	DNA topoisomerase III [Bacillus cereus].	33.94	654	383	21	3	627	5	638	5e-86	297
rs:WP_021364630	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.64	654	370	21	3	631	5	619	5e-86	296
rs:WP_040397454	DNA topoisomerase [Anaerococcus senegalensis].	34.90	576	332	14	1	564	1	545	5e-86	293
rs:WP_046392322	DNA topoisomerase III [Bacillus cereus].	34.15	656	379	22	3	627	5	638	5e-86	297
rs:WP_032428827	DNA topoisomerase III [Klebsiella pneumoniae].	33.17	618	360	21	1	581	1	602	5e-86	295
rs:WP_045347463	DNA topoisomerase III [Enterobacter cloacae].	32.35	612	373	18	1	581	1	602	5e-86	295
tr:A0A023X4M0_9ACTN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.72	736	461	18	1	680	1	721	5e-86	297
rs:WP_000047299	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	33.94	654	383	21	3	627	5	638	5e-86	297
rs:WP_000047301	DNA topoisomerase III [Bacillus cereus].	33.94	654	383	21	3	627	5	638	5e-86	297
rs:WP_034820457	DNA topoisomerase [[Eubacterium] nodatum].	35.56	599	340	15	1	587	1	565	5e-86	293
rs:WP_044271898	DNA topoisomerase I [Candidatus Bacteroides timonensis].	31.81	701	429	21	1	676	1	677	5e-86	296
rs:WP_000047300	MULTISPECIES: DNA topoisomerase III [Bacillus].	33.94	654	383	21	3	627	5	638	5e-86	297
rs:WP_025117795	DNA topoisomerase III [Bacillus sp. H1m].	33.99	656	380	22	3	627	5	638	5e-86	297
rs:WP_006916694	DNA topoisomerase III [Bacillus sp. GeD10].	34.15	656	379	22	3	627	5	638	5e-86	297
rs:WP_004203795	MULTISPECIES: DNA topoisomerase III [Klebsiella].	33.17	618	360	21	1	581	1	602	5e-86	295
rs:WP_024741910	DNA topoisomerase III [Tenacibaculum maritimum].	31.02	722	435	20	1	678	1	703	5e-86	298
rs:WP_013097044	DNA topoisomerase III [Enterobacter cloacae].	31.86	609	380	15	1	581	1	602	5e-86	295
rs:WP_045135044	DNA topoisomerase III [Enterobacter cloacae].	31.64	610	380	16	1	581	1	602	5e-86	295
rs:WP_022997579	hypothetical protein [Alcanivorax sp. PN-3].	29.92	712	433	18	5	671	6	696	6e-86	296
rs:WP_009653400	DNA topoisomerase III [Klebsiella sp. OBRC7].	33.06	611	370	18	1	581	1	602	6e-86	295
rs:WP_032308776	DNA topoisomerase III [Escherichia coli].	29.44	642	411	16	1	614	1	628	6e-86	295
rs:WP_028086447	DNA topoisomerase III [Dorea longicatena].	31.85	697	421	19	1	671	1	669	6e-86	296
rs:WP_021426535	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.49	654	371	21	3	631	5	619	6e-86	296
rs:WP_000047279	DNA topoisomerase III [Bacillus cereus].	33.94	654	383	21	3	627	5	638	6e-86	297
rs:WP_016083678	DNA topoisomerase 3 [Bacillus cereus].	34.30	656	378	22	3	627	5	638	6e-86	297
rs:WP_021362717	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.64	654	370	21	3	631	5	619	6e-86	296
rs:WP_014831514	DNA topoisomerase III [Enterobacter cloacae].	31.86	609	380	15	1	581	1	602	6e-86	295
rs:WP_007955891	DNA topoisomerase III [Pelosinus fermentans].	32.99	670	394	21	3	638	5	653	6e-86	297
rs:WP_009064311	DNA topoisomerase III [Clostridium sp. MSTE9].	30.65	708	441	17	1	683	1	683	6e-86	296
rs:WP_045415135	DNA topoisomerase III [Enterobacter asburiae].	31.69	609	381	15	1	581	1	602	6e-86	295
rs:WP_028904646	DNA topoisomerase III [Prevotella intermedia].	32.26	620	378	13	1	590	1	608	6e-86	294
rs:WP_034288830	DNA topoisomerase III [Bacillus sp. 72].	33.08	653	383	21	3	627	5	631	6e-86	296
rs:WP_044307355	DNA topoisomerase III [Bacillus cereus].	34.15	656	379	22	3	627	5	638	6e-86	297
rs:WP_012008960	DNA topoisomerase III [Bacillus pumilus].	33.18	648	394	17	3	627	5	636	6e-86	297
rs:WP_047023740	DNA topoisomerase III [Enterobacter sp. GN02174].	31.86	609	380	15	1	581	1	602	6e-86	295
rs:WP_019821571	DNA topoisomerase III [Vibrio splendidus].	29.26	704	439	18	1	669	1	680	6e-86	296
rs:WP_023299889	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	32.52	612	372	18	1	581	1	602	6e-86	295
rs:WP_016117101	DNA topoisomerase 3 [Bacillus cereus].	33.94	654	383	21	3	627	5	638	6e-86	297
rs:WP_035566908	DNA topoisomerase III [Hymenobacter sp. IS2118].	29.26	745	436	20	1	668	1	731	6e-86	300
rs:WP_025815981	DNA topoisomerase III [Prevotella shahii].	31.79	689	397	19	1	629	1	676	6e-86	296
rs:WP_021421634	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.64	654	370	21	3	631	5	619	6e-86	296
rs:WP_047352559	DNA topoisomerase III [Enterobacter sp. GN02616].	32.02	609	379	16	1	581	1	602	7e-86	294
rs:WP_003214040	DNA topoisomerase III [Bacillus pumilus].	33.18	648	394	17	3	627	5	636	7e-86	297
rs:WP_008110196	DNA topoisomerase III [Pseudoalteromonas sp. BSi20311].	32.51	606	365	13	1	574	1	594	7e-86	295
rs:WP_026695925	DNA topoisomerase III [Bacillus kribbensis].	32.77	650	397	19	2	627	4	637	7e-86	296
rs:WP_047225405	DNA topoisomerase III [Bacillus thuringiensis].	33.94	654	383	21	3	627	5	638	7e-86	296
rs:WP_038684866	hypothetical protein, partial [Rubrobacter radiotolerans].	27.72	736	461	18	1	680	1	721	7e-86	296
rs:WP_014228966	MULTISPECIES: DNA topoisomerase III [Klebsiella].	33.06	611	370	18	1	581	1	602	7e-86	295
rs:WP_038979877	MULTISPECIES: DNA topoisomerase III [Enterobacter].	31.86	609	380	15	1	581	1	602	7e-86	294
rs:WP_045363723	DNA topoisomerase III [Enterobacter aerogenes].	33.55	614	363	21	1	581	1	602	7e-86	295
rs:WP_045374815	DNA topoisomerase III [Enterobacter aerogenes].	33.39	614	364	21	1	581	1	602	7e-86	295
rs:WP_038901156	DNA topoisomerase III [Dickeya dadantii].	31.48	667	391	23	1	627	1	641	7e-86	294
rs:WP_021408466	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.49	654	371	21	3	631	5	619	7e-86	296
rs:WP_032619841	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	32.19	612	374	18	1	581	1	602	8e-86	294
rs:WP_023305946	DNA topoisomerase III [Enterobacter cloacae].	32.52	612	372	18	1	581	1	602	8e-86	294
rs:WP_038415875	DNA topoisomerase III [Enterobacter cloacae].	32.52	612	372	18	1	581	1	602	8e-86	294
rs:WP_022647797	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	32.52	612	372	18	1	581	1	602	8e-86	294
rs:WP_045393274	DNA topoisomerase III [Enterobacter aerogenes].	33.33	615	363	22	1	581	1	602	8e-86	295
tr:A0A0A5S663_KLEOX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.06	611	370	18	1	581	1	602	8e-86	295
rs:WP_004371446	DNA topoisomerase III [Prevotella oris].	30.67	701	396	19	1	624	1	688	8e-86	296
rs:WP_000047296	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	33.94	654	383	21	3	627	5	638	8e-86	296
rs:WP_046177003	DNA topoisomerase [Streptococcus dysgalactiae].	34.22	599	351	14	1	587	1	568	8e-86	292
rs:WP_000209240	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	31.72	722	433	22	3	682	4	707	8e-86	296
rs:WP_030022716	DNA topoisomerase III [Bacillus thuringiensis].	33.79	654	384	21	3	627	5	638	8e-86	296
rs:WP_000047280	DNA topoisomerase III [Bacillus thuringiensis].	33.99	656	380	22	3	627	5	638	9e-86	296
rs:WP_047364334	DNA topoisomerase III [Enterobacter sp. GN02283].	31.69	609	381	15	1	581	1	602	9e-86	294
rs:WP_031453405	DNA topoisomerase III [Flavobacterium chungangense].	30.89	722	426	23	1	680	1	691	9e-86	297
rs:WP_039977192	DNA topoisomerase III [Vibrio jasicida].	29.76	709	434	20	1	669	1	685	9e-86	296
rs:WP_000209236	DNA topoisomerase III [Bacillus cereus].	31.30	722	436	21	3	682	4	707	9e-86	296
rs:WP_036866402	DNA topoisomerase III [Prevotella bivia].	32.63	613	365	15	1	581	1	597	9e-86	293
rs:WP_040555026	DNA topoisomerase III [Prevotella multiformis].	31.61	620	382	14	1	590	1	608	9e-86	294
rs:WP_006947859	DNA topoisomerase III [Prevotella marshii].	30.89	683	397	19	1	630	1	661	9e-86	295
rs:WP_021992003	DNA topoisomerase III [Prevotella sp. CAG:1092].	30.35	705	404	17	1	630	1	693	9e-86	296
rs:WP_004570515	DNA topoisomerase III [Polaribacter irgensii].	31.77	724	418	24	1	676	1	696	9e-86	298
rs:WP_045307963	DNA topoisomerase III [Enterobacter sp. 36796].	32.35	612	373	17	1	581	1	602	9e-86	294
rs:WP_008688070	DNA topoisomerase III [Eubacterium sp. 3_1_31].	32.08	692	426	19	1	671	1	669	9e-86	295
rs:WP_040017237	DNA topoisomerase III [Enterobacter ludwigii].	31.69	609	381	15	1	581	1	602	9e-86	294
rs:WP_017553252	DNA topoisomerase III [Bacillus coagulans].	31.67	663	392	21	3	646	4	624	9e-86	295
rs:WP_010390952	DNA topoisomerase III [Pseudoalteromonas undina].	33.33	606	360	15	1	574	1	594	9e-86	294
rs:WP_045346457	DNA topoisomerase III [Enterobacter cloacae].	32.52	612	372	18	1	581	1	602	1e-85	294
rs:WP_003728632	DNA topoisomerase III [Listeria monocytogenes].	32.72	651	381	18	3	627	5	624	1e-85	296
rs:WP_016133523	DNA topoisomerase 3 [Bacillus cereus].	33.99	656	380	22	3	627	5	638	1e-85	296
rs:WP_044906257	DNA topoisomerase III [[Clostridium] innocuum].	30.27	697	424	22	1	671	1	661	1e-85	295
rs:WP_015840206	DNA topoisomerase III [Pectobacterium carotovorum].	32.15	619	365	19	1	581	1	602	1e-85	294
rs:WP_042678820	DNA topoisomerase III [Anaerosalibacter sp. ND1].	33.33	651	390	19	3	627	5	637	1e-85	296
rs:WP_045630122	DNA topoisomerase III [Enterobacter cloacae].	31.69	609	381	15	1	581	1	602	1e-85	294
rs:WP_022617262	DNA topoisomerase III [Peptoclostridium difficile].	33.49	654	371	21	3	631	5	619	1e-85	296
rs:WP_005815481	DNA topoisomerase III [Desulfitobacterium hafniense].	31.90	652	398	17	3	627	5	637	1e-85	296
rs:WP_040104610	DNA topoisomerase III [Salinicoccus roseus].	31.95	651	398	18	3	627	5	636	1e-85	296
rs:WP_044707194	DNA topoisomerase III [Escherichia coli].	29.44	642	411	16	1	614	1	628	1e-85	295
rs:WP_000047287	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	33.79	654	384	21	3	627	5	638	1e-85	296
rs:WP_036885935	DNA topoisomerase III [Prevotella bivia].	32.63	613	365	15	1	581	1	597	1e-85	293
rs:WP_007931300	MULTISPECIES: DNA topoisomerase III [Pelosinus].	32.99	670	394	21	3	638	5	653	1e-85	296
rs:WP_000047278	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	33.99	656	380	22	3	627	5	638	1e-85	296
rs:WP_023940994	MULTISPECIES: DNA topoisomerase III [Porphyromonas].	31.89	646	400	19	1	624	1	628	1e-85	295
rs:WP_028017189	DNA topoisomerase III [Enterobacter cloacae].	31.86	609	380	15	1	581	1	602	1e-85	294
rs:WP_046465821	DNA topoisomerase III [Staphylococcus equorum].	34.29	630	373	17	3	615	4	609	1e-85	296
rs:WP_000047286	DNA topoisomerase III [Bacillus cereus].	33.79	654	384	21	3	627	5	638	1e-85	296
rs:WP_016097640	DNA topoisomerase 3 [Bacillus cereus].	33.99	656	380	22	3	627	5	638	1e-85	296
rs:WP_023937515	DNA topoisomerase III [Porphyromonas crevioricanis].	31.89	646	400	20	1	624	1	628	1e-85	295
rs:WP_046878585	DNA topoisomerase III [Klebsiella oxytoca].	33.06	611	370	18	1	581	1	602	1e-85	294
rs:WP_036979860	DNA topoisomerase III [Pseudoalteromonas sp. SCSIO_11900].	32.48	628	377	14	1	596	1	613	1e-85	294
rs:WP_032099574	DNA topoisomerase III [Anoxybacillus flavithermus].	30.62	725	453	20	1	687	1	713	1e-85	296
rs:WP_033808633	DNA topoisomerase III [Escherichia coli].	29.44	642	411	16	1	614	1	628	1e-85	295
rs:WP_045146679	DNA topoisomerase III [Peptoclostridium difficile].	33.33	654	372	21	3	631	5	619	1e-85	296
rs:WP_016089486	DNA topoisomerase 3 [Bacillus cereus].	33.54	659	379	22	3	627	5	638	1e-85	296
rs:WP_047368337	DNA topoisomerase III [Enterobacter sp. GN02548].	31.69	609	381	15	1	581	1	602	1e-85	294
rs:WP_023059217	DNA topoisomerase III [Peptoniphilus sp. BV3AC2].	34.72	576	333	14	1	564	1	545	1e-85	292
rs:WP_012575131	DNA topoisomerase III [Anoxybacillus flavithermus].	30.57	723	456	18	1	687	1	713	1e-85	296
rs:WP_047051503	DNA topoisomerase III [Enterobacter cloacae].	32.35	612	373	18	1	581	1	602	1e-85	294
rs:WP_046150268	DNA topoisomerase III [Parabacteroides sp. HGS0025].	29.86	700	424	16	1	650	1	683	1e-85	295
rs:WP_022302692	DNA topoisomerase [Firmicutes bacterium CAG:227].	33.43	658	387	21	3	627	4	643	1e-85	296
rs:WP_004336120	DNA topoisomerase III [Prevotella bivia].	32.63	613	365	15	1	581	1	597	1e-85	293
rs:WP_011462224	DNA topoisomerase III [Desulfitobacterium hafniense].	31.90	652	398	17	3	627	5	637	1e-85	296
rs:WP_021897294	DNA topoisomerase III [Prevotella sp. CAG:924].	30.68	665	401	17	1	621	1	649	1e-85	294
rs:WP_013238995	MULTISPECIES: DNA topoisomerase III [Clostridium].	32.09	645	381	20	3	615	5	624	1e-85	296
rs:WP_035147711	DNA topoisomerase III [Clostridium tetanomorphum].	32.62	650	397	18	3	627	5	638	1e-85	296
rs:WP_023332748	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	31.69	609	381	15	1	581	1	602	1e-85	294
rs:WP_023318003	DNA topoisomerase III [Klebsiella pneumoniae].	32.96	619	360	22	1	581	1	602	1e-85	294
rs:WP_004334692	DNA topoisomerase III [Porphyromonas endodontalis].	32.41	614	375	14	1	587	1	601	1e-85	293
rs:WP_029595302	DNA topoisomerase III [Exiguobacterium sp. GIC31].	30.66	685	435	16	1	653	1	677	1e-85	295
rs:WP_045973488	DNA topoisomerase III [Xenorhabdus doucetiae].	32.46	610	375	15	1	581	1	602	1e-85	294
rs:WP_007785444	DNA topoisomerase III [Desulfosporosinus youngiae].	31.70	653	399	17	3	627	5	638	1e-85	296
rs:WP_022211736	DNA topoisomerase III [Clostridium sp. CAG:265].	32.93	659	380	22	3	627	5	635	1e-85	296
rs:WP_022158033	DNA topoisomerase III [Prevotella sp. CAG:520].	30.68	704	399	20	1	629	1	690	1e-85	295
rs:WP_021388038	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.49	654	371	21	3	631	5	619	1e-85	295
rs:WP_003430396	DNA topoisomerase III [Peptoclostridium difficile].	33.49	654	371	21	3	631	5	619	1e-85	295
rs:WP_027639809	DNA topoisomerase III [Clostridium cadaveris].	32.52	658	386	20	3	627	5	637	1e-85	296
rs:WP_045524206	DNA topoisomerase III [Bacillus niacini].	31.17	738	426	25	1	682	1	712	1e-85	296
rs:WP_010618764	DNA topoisomerase III [Plautia stali symbiont].	32.68	612	357	19	1	574	1	595	1e-85	293
rs:WP_025790876	DNA topoisomerase III [Prevotella histicola].	33.54	635	364	18	1	590	1	622	1e-85	293
rs:WP_025842430	DNA topoisomerase III [Porphyromonas gingivicanis].	33.17	612	361	18	1	581	1	595	1e-85	293
rs:WP_036786249	DNA topoisomerase III [Polaribacter sp. Hel1_33_49].	30.13	717	442	21	1	678	1	697	1e-85	297
rs:WP_007579075	DNA topoisomerase III [Patulibacter medicamentivorans].	29.30	744	448	25	3	680	5	736	1e-85	297
tr:U4P5E3_CLOBB	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.08	650	392	18	4	627	1	633	1e-85	296
rs:WP_038918989	DNA topoisomerase III [Dickeya sp. MK7].	31.33	664	396	22	1	627	1	641	2e-85	293
rs:WP_029283165	DNA topoisomerase III [Bacillus indicus].	33.18	648	392	18	4	627	6	636	2e-85	296
rs:WP_021285572	DNA topoisomerase III [Clostridium sp. BL8].	32.88	657	386	21	3	627	5	638	2e-85	296
rs:WP_045285254	DNA topoisomerase III [Enterobacter sp. 35699].	32.02	609	379	15	1	581	1	602	2e-85	293
rs:WP_022191868	hypothetical protein [Parabacteroides sp. CAG:2].	29.84	707	418	18	1	647	1	689	2e-85	295
rs:WP_045338920	DNA topoisomerase III [Enterobacter cloacae].	32.19	612	374	18	1	581	1	602	2e-85	293
rs:WP_005934783	DNA topoisomerase III [Faecalibacterium prausnitzii].	30.97	649	397	17	1	627	1	620	2e-85	295
rs:WP_002139479	DNA topoisomerase III [Bacillus cereus].	33.84	656	381	22	3	627	5	638	2e-85	296
rs:WP_019721174	DNA topoisomerase III [Bacillus coagulans].	31.52	663	393	21	3	646	4	624	2e-85	295
rs:WP_045327023	DNA topoisomerase III [Enterobacter asburiae].	31.86	609	380	15	1	581	1	602	2e-85	293
rs:WP_038216568	DNA topoisomerase III [Xenorhabdus bovienii].	31.87	640	387	16	1	611	1	620	2e-85	294
rs:WP_045261603	DNA topoisomerase III [Enterobacter sp. 35669].	31.69	609	381	15	1	581	1	602	2e-85	293
rs:WP_015063384	DNA topoisomerase [Burkholderia cepacia].	30.93	653	402	16	1	614	1	643	2e-85	295
rs:WP_047062623	DNA topoisomerase III [Enterobacter cloacae].	32.19	612	374	18	1	581	1	602	2e-85	293
rs:WP_038916231	DNA topoisomerase III [Dickeya zeae].	31.02	619	372	18	1	581	1	602	2e-85	293
rs:WP_018305366	DNA topoisomerase III [Desulfitobacterium hafniense].	31.90	652	398	17	3	627	5	637	2e-85	296
rs:WP_041910472	DNA topoisomerase III [Enterobacter sp. BIDMC 29].	31.69	609	381	15	1	581	1	602	2e-85	293
rs:WP_022510519	DNA topoisomerase [Prevotella sp. CAG:617].	30.42	687	404	19	1	630	1	670	2e-85	295
rs:WP_004850046	DNA topoisomerase III [Klebsiella oxytoca].	32.90	611	371	18	1	581	1	602	2e-85	294
rs:WP_032688194	MULTISPECIES: DNA topoisomerase III [Raoultella].	32.84	612	370	19	1	581	1	602	2e-85	293
rs:WP_009229127	DNA topoisomerase III [Prevotella sp. oral taxon 317].	32.85	624	386	16	1	605	1	610	2e-85	295
rs:WP_041845841	DNA topoisomerase III [Bacillus thermoamylovorans].	31.72	618	382	13	3	611	4	590	2e-85	295
rs:WP_045406323	DNA topoisomerase III [Enterobacter asburiae].	31.69	609	381	15	1	581	1	602	2e-85	293
rs:WP_027477969	DNA topoisomerase III [Curvibacter gracilis].	31.87	640	391	15	1	612	1	623	2e-85	295
rs:WP_032695843	DNA topoisomerase III [Raoultella planticola].	32.84	612	370	19	1	581	1	602	2e-85	293
rs:WP_040036331	DNA topoisomerase III [Bacillaceae bacterium MTCC 10057].	30.22	695	446	15	1	661	1	690	2e-85	295
rs:WP_035445052	DNA topoisomerase III, partial [Bacillus sp. UNC41MFS5].	30.51	731	440	22	1	682	1	712	2e-85	295
rs:WP_015729516	DNA topoisomerase III [Staphylococcus pseudintermedius].	32.80	628	384	16	3	615	5	609	2e-85	295
rs:WP_024998619	DNA topoisomerase III [Prevotella falsenii].	32.53	621	375	15	1	590	1	608	2e-85	293
rs:WP_040208500	MULTISPECIES: DNA topoisomerase III [Bacillus].	31.01	732	435	23	1	682	1	712	2e-85	295
rs:WP_023343916	DNA topoisomerase III [Enterobacter sp. MGH 16].	31.69	609	381	15	1	581	1	602	2e-85	293
rs:WP_023335338	DNA topoisomerase III [Enterobacter sp. MGH 24].	31.86	609	380	15	1	581	1	602	2e-85	293
rs:WP_016837347	DNA topoisomerase III [Ureibacillus thermosphaericus].	32.57	651	395	18	3	627	5	637	2e-85	295
rs:WP_039232415	DNA topoisomerase III [Bacillus thermotolerans].	30.22	695	446	15	1	661	1	690	2e-85	295
rs:WP_008500701	MULTISPECIES: DNA topoisomerase III [Enterobacter].	31.69	609	381	15	1	581	1	602	2e-85	293
rs:WP_044795633	DNA topoisomerase III [Bacillus cereus].	33.79	654	384	21	3	627	5	638	2e-85	295
rs:WP_000047281	DNA topoisomerase III [Bacillus cereus].	33.64	654	385	21	3	627	5	638	2e-85	295
rs:WP_040597623	DNA topoisomerase III [Alloprevotella rava].	30.33	699	400	20	1	629	1	682	2e-85	295
rs:WP_025757378	DNA topoisomerase III [Enterobacter cloacae].	31.86	609	380	15	1	581	1	602	2e-85	293
rs:WP_005858139	DNA topoisomerase III [Parabacteroides distasonis].	30.20	702	420	19	1	647	1	687	2e-85	295
tr:A6LCM5_PARD8	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:ABR43439.1};	30.20	702	420	19	1	647	2	688	2e-85	295
rs:WP_041240562	hypothetical protein, partial [Gordonibacter pamelaeae].	29.35	712	439	19	3	667	4	698	2e-85	295
rs:WP_006799305	DNA topoisomerase III [Dysgonomonas gadei].	29.86	710	425	16	1	650	1	697	2e-85	295
rs:WP_016219336	DNA topoisomerase III [Dorea sp. 5-2].	28.27	711	459	16	1	683	1	688	2e-85	295
rs:WP_026825790	DNA topoisomerase III [Exiguobacterium marinum].	30.43	713	451	18	1	679	1	702	2e-85	295
rs:WP_017384681	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	32.19	612	374	18	1	581	1	602	2e-85	293
rs:WP_045331141	DNA topoisomerase III [Enterobacter cloacae].	32.19	612	374	18	1	581	1	602	2e-85	293
rs:WP_043610175	DNA topoisomerase III, partial [Desulfovibrio sp. A2].	28.15	675	419	14	3	623	5	667	2e-85	294
rs:WP_038911181	DNA topoisomerase III [Dickeya dadantii].	31.33	667	392	23	1	627	1	641	2e-85	293
rs:WP_016128093	DNA topoisomerase III [Bacillus cereus].	30.61	722	441	20	3	682	4	707	2e-85	295
rs:WP_036871357	DNA topoisomerase III [Prevotella histicola].	33.23	635	366	18	1	590	1	622	2e-85	293
rs:WP_011878189	DNA topoisomerase III [Desulfotomaculum reducens].	31.33	699	435	19	2	673	3	683	2e-85	295
rs:WP_004140407	DNA topoisomerase III [Klebsiella pneumoniae].	33.22	614	365	20	1	581	1	602	2e-85	293
rs:WP_029093488	DNA topoisomerase III [Budvicia aquatica].	32.31	616	368	16	1	581	1	602	2e-85	293
rs:WP_009274928	MULTISPECIES: DNA topoisomerase III [Parabacteroides].	30.07	705	417	19	1	647	1	687	2e-85	295
rs:WP_016998796	hypothetical protein [Staphylococcus lentus].	32.11	626	392	13	3	615	4	609	2e-85	295
rs:WP_045338463	DNA topoisomerase III [Enterobacter cloacae].	32.19	612	374	18	1	581	1	602	2e-85	293
rs:WP_035437661	DNA topoisomerase III [Bacillus sp. UNC322MFChir4.1].	34.45	656	377	23	3	627	5	638	2e-85	295
rs:WP_000047319	DNA topoisomerase III [Bacillus thuringiensis].	34.15	656	379	22	3	627	5	638	2e-85	295
rs:WP_035782818	DNA topoisomerase III [Clostridium botulinum].	33.08	653	390	18	3	627	5	638	2e-85	295
rs:WP_032651511	DNA topoisomerase III [Enterobacter cloacae].	31.69	609	381	15	1	581	1	602	3e-85	293
rs:WP_034806015	DNA topoisomerase III [Exiguobacterium sp. AB2].	30.28	710	452	16	1	676	1	701	3e-85	295
rs:WP_004254081	DNA topoisomerase III [Providencia rettgeri].	32.80	628	362	20	1	586	1	610	3e-85	293
rs:WP_028728532	DNA topoisomerase III [Parabacteroides gordonii].	30.00	700	423	17	1	650	1	683	3e-85	294
rs:WP_009530372	DNA topoisomerase III [Peptostreptococcaceae bacterium OBRC8].	31.70	653	407	16	1	638	1	629	3e-85	294
rs:WP_023655212	DNA topoisomerase III [Erwinia piriflorinigrans].	32.90	620	359	21	1	581	1	602	3e-85	293
rs:WP_022429476	DNA topoisomerase III [Prevotella stercorea CAG:629].	30.73	703	399	20	1	629	1	689	3e-85	294
rs:WP_036945020	DNA topoisomerase III [Pseudobacteroides cellulosolvens].	31.59	649	403	17	3	627	5	636	3e-85	295
tr:G5GB63_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.33	699	400	20	1	629	38	719	3e-85	295
rs:WP_039029035	DNA topoisomerase III [Leclercia adecarboxylata].	31.40	602	378	14	1	574	1	595	3e-85	293
rs:WP_016324269	DNA topoisomerase III [Oscillibacter sp. 1-3].	30.69	694	435	17	2	670	5	677	3e-85	295
rs:WP_003205730	MULTISPECIES: DNA topoisomerase III [Bacillus].	33.94	654	383	21	3	627	5	638	3e-85	295
rs:WP_001235864	DNA topoisomerase III [Salmonella enterica].	31.40	656	402	21	1	623	1	641	3e-85	293
rs:WP_004225438	DNA topoisomerase III [Klebsiella pneumoniae].	33.22	614	365	20	1	581	1	602	3e-85	293
rs:WP_000047295	DNA topoisomerase III [Bacillus cereus].	33.94	654	383	21	3	627	5	638	3e-85	295
rs:WP_036890366	DNA topoisomerase III [Porphyromonas crevioricanis].	31.89	646	400	19	1	624	1	628	3e-85	293
tr:W7CFI9_BROTH	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.62	653	390	16	3	631	4	630	3e-85	294
rs:WP_021398054	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.49	654	371	21	3	631	5	619	3e-85	295
rs:WP_028389303	hypothetical protein [Legionella fairfieldensis].	31.25	672	415	17	1	640	1	657	3e-85	293
rs:WP_015945463	DNA topoisomerase III [Desulfitobacterium hafniense].	31.75	652	399	17	3	627	5	637	3e-85	295
rs:WP_035202627	DNA topoisomerase III [Bacillus clausii].	31.03	725	440	19	1	683	1	707	3e-85	295
rs:WP_033142648	DNA topoisomerase III [Blautia producta].	31.41	659	401	18	3	627	4	645	3e-85	295
rs:WP_013271000	DNA topoisomerase III [[Clostridium] saccharolyticum].	32.01	656	395	18	3	627	4	639	3e-85	295
rs:WP_022633477	DNA topoisomerase III [Dickeya solani].	30.87	664	399	20	1	627	1	641	3e-85	293
rs:WP_006809125	MULTISPECIES: DNA topoisomerase III [Enterobacter].	31.52	625	390	16	1	597	1	615	3e-85	293
rs:WP_020491229	hypothetical protein [Dehalobacter sp. FTH1].	29.63	702	434	20	1	673	1	671	3e-85	294
rs:WP_004250914	DNA topoisomerase III [Proteus mirabilis].	33.66	612	365	17	1	581	1	602	3e-85	293
rs:WP_002130832	DNA topoisomerase III [Bacillus cereus].	33.84	656	381	22	3	627	5	638	3e-85	295
rs:WP_023296331	DNA topoisomerase III [Enterobacter cloacae].	32.19	612	374	18	1	581	1	602	3e-85	293
rs:WP_032718932	DNA topoisomerase III [Klebsiella oxytoca].	31.41	608	388	11	1	587	1	600	3e-85	292
rs:WP_022241545	DNA topoisomerase III [Clostridium sp. CAG:413].	30.82	649	409	17	3	627	5	637	3e-85	295
rs:WP_046336289	DNA topoisomerase III [Xenorhabdus bovienii].	31.35	638	393	14	1	611	1	620	3e-85	293
tr:D6DF30_CLOSC	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.41	697	443	17	1	671	1	674	3e-85	294
rs:WP_016103242	DNA topoisomerase 3 [Bacillus cereus].	33.79	654	384	22	3	627	5	638	3e-85	295
rs:WP_009003768	DNA topoisomerase III [Clostridium sp. D5].	32.52	655	393	19	3	627	4	639	3e-85	295
rs:WP_036575330	DNA topoisomerase III [Oceanobacillus picturae].	32.71	645	398	17	3	626	5	634	3e-85	295
rs:WP_025719153	DNA topoisomerase III [Paenibacillus sp. 1-18].	30.72	638	383	18	3	615	4	607	3e-85	294
rs:WP_027156703	DNA topoisomerase [Methylobacter luteus].	31.76	614	377	13	1	579	1	607	3e-85	294
rs:WP_021375833	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.33	654	372	21	3	631	5	619	3e-85	294
rs:WP_023157825	DNA topoisomerase [Klebsiella pneumoniae].	29.90	679	423	18	1	646	1	659	4e-85	293
rs:WP_016304003	DNA topoisomerase III [Lachnospiraceae bacterium A2].	31.79	648	390	16	3	615	4	634	4e-85	295
tr:C2XNU9_BACCE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.84	656	381	22	3	627	9	642	4e-85	295
rs:WP_002140241	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	33.49	654	386	21	3	627	5	638	4e-85	295
rs:WP_033798013	DNA topoisomerase III [Bacillus mycoides].	34.15	656	379	23	3	627	5	638	4e-85	295
rs:WP_022254546	DNA topoisomerase [Firmicutes bacterium CAG:466].	31.63	664	411	18	3	636	5	655	4e-85	295
rs:WP_005866302	MULTISPECIES: DNA topoisomerase III [Parabacteroides].	29.69	704	425	17	1	647	1	691	4e-85	294
rs:WP_038036807	DNA topoisomerase III [Thioalkalivibrio sp. ALE20].	29.01	710	404	16	41	670	1	690	4e-85	294
tr:A0A0B6X684_XENBV	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.35	638	393	14	1	611	10	629	4e-85	293
rs:WP_008879173	MULTISPECIES: DNA topoisomerase III [Geobacillus].	31.42	662	395	19	3	646	4	624	4e-85	294
rs:WP_016097005	DNA topoisomerase 3 [Bacillus cereus].	33.84	656	381	22	3	627	5	638	4e-85	295
rs:WP_032728100	DNA topoisomerase III [Klebsiella oxytoca].	32.40	645	388	20	1	615	1	627	4e-85	293
rs:WP_003356144	DNA topoisomerase III [Clostridium botulinum].	32.69	676	389	26	3	638	5	654	4e-85	295
rs:WP_032650922	MULTISPECIES: DNA topoisomerase III [Enterobacter].	31.69	609	381	15	1	581	1	602	4e-85	292
rs:WP_040045076	DNA topoisomerase III [Hafnia alvei].	32.85	615	366	18	1	581	1	602	4e-85	292
rs:WP_045910241	DNA topoisomerase III [Enterobacter cloacae].	31.69	609	381	15	1	581	1	602	4e-85	292
rs:WP_033706351	DNA topoisomerase III [Bacillus cereus].	33.84	656	381	22	3	627	5	638	4e-85	295
rs:WP_013656949	DNA topoisomerase III [Cellulosilyticum lentocellum].	31.80	629	396	14	3	615	5	616	4e-85	295
rs:WP_034527038	DNA topoisomerase III [Bacteroides sp. 3_1_19].	29.99	707	417	19	1	647	1	689	4e-85	294
rs:WP_020947509	hypothetical protein [Klebsiella pneumoniae].	33.22	614	365	20	1	581	1	602	4e-85	293
rs:WP_004377279	DNA topoisomerase III [Prevotella oris].	30.96	701	394	20	1	624	1	688	4e-85	294
tr:C2Q4N3_BACCE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.49	654	386	21	3	627	9	642	4e-85	295
rs:WP_000047297	DNA topoisomerase III [Bacillus cereus].	33.79	654	384	21	3	627	5	638	4e-85	295
rs:WP_039529009	DNA topoisomerase III [Pectobacterium carotovorum].	32.15	619	365	20	1	581	1	602	4e-85	292
rs:WP_014542454	DNA topoisomerase III [Erwinia sp. Ejp617].	30.51	662	418	13	1	633	1	649	4e-85	293
tr:W2C565_9PORP	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.35	603	386	14	1	583	1	589	4e-85	291
rs:WP_023639754	DNA topoisomerase III [Dickeya zeae].	31.18	619	371	18	1	581	1	602	4e-85	292
rs:WP_032674572	DNA topoisomerase III [Enterobacter cloacae].	31.69	609	381	15	1	581	1	602	5e-85	292
rs:WP_041903320	DNA topoisomerase III [Bacillus thermoamylovorans].	31.07	618	386	12	3	611	4	590	5e-85	294
rs:WP_024559605	DNA topoisomerase III [Cronobacter pulveris].	31.23	618	372	17	1	581	1	602	5e-85	293
tr:C2SEV4_BACCE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.84	656	381	22	3	627	9	642	5e-85	295
rs:WP_026570896	DNA topoisomerase III [Bacillus sp. NSP22.2].	32.10	648	399	18	3	626	5	635	5e-85	294
rs:WP_022399462	DNA topoisomerase III [Roseburia sp. CAG:471].	30.98	723	422	20	1	679	1	690	5e-85	293
rs:WP_008807619	MULTISPECIES: DNA topoisomerase III [Klebsiella].	32.52	615	368	18	1	581	1	602	5e-85	292
rs:WP_002124971	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	33.84	656	381	22	3	627	5	638	5e-85	295
rs:WP_024908566	DNA topoisomerase III [Enterobacter asburiae].	31.69	609	381	15	1	581	1	602	5e-85	292
rs:WP_000366638	DNA topoisomerase [Streptococcus agalactiae].	34.44	601	347	15	1	587	1	568	5e-85	290
rs:WP_001696682	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	29.75	642	409	16	1	614	1	628	5e-85	293
rs:WP_007716460	DNA topoisomerase III [[Clostridium] asparagiforme].	28.59	717	454	19	1	683	1	693	5e-85	294
rs:WP_023297427	MULTISPECIES: DNA topoisomerase III [Klebsiella].	31.90	649	386	20	1	615	1	627	5e-85	292
rs:WP_004039093	DNA topoisomerase III [Clostridium sp. ASF356].	32.06	655	400	18	1	636	1	629	5e-85	293
rs:WP_012726527	DNA topoisomerase III [Exiguobacterium sp. AT1b].	30.66	711	450	18	1	678	1	701	5e-85	294
tr:F0F5I7_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.55	618	381	14	1	588	93	698	5e-85	294
rs:WP_039490448	MULTISPECIES: DNA topoisomerase III [Pseudoalteromonas].	32.57	614	368	12	1	579	1	603	5e-85	292
rs:WP_016160745	MULTISPECIES: DNA topoisomerase III [Klebsiella].	31.90	649	386	20	1	615	1	627	5e-85	292
rs:WP_042457656	DNA topoisomerase III [Bacillus sp. FF4].	29.66	725	454	16	1	682	1	712	5e-85	294
rs:WP_025271989	DNA topoisomerase [Streptococcus anginosus].	34.05	602	348	14	1	587	1	568	5e-85	290
rs:WP_032663739	DNA topoisomerase III [Enterobacter cloacae].	31.69	609	381	15	1	581	1	602	5e-85	292
rs:WP_031943975	DNA topoisomerase [uncultured bacterium pMCBF6].	31.80	654	394	17	1	614	1	642	5e-85	293
rs:WP_016941287	DNA topoisomerase III [Dickeya zeae].	31.02	619	372	18	1	581	1	602	5e-85	292
rs:WP_009766587	DNA topoisomerase III [Sporosarcina newyorkensis].	32.82	655	391	20	3	627	5	640	5e-85	294
rs:WP_009903124	DNA topoisomerase III [Peptoclostridium difficile].	33.49	654	371	21	3	631	5	619	5e-85	294
tr:A0A098B862_DESHA	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.75	652	399	17	3	627	5	637	5e-85	294
rs:WP_017146088	DNA topoisomerase III [Klebsiella oxytoca].	32.40	645	388	20	1	615	1	627	6e-85	292
rs:WP_046050872	DNA topoisomerase III [Yersinia enterocolitica].	31.93	617	369	20	1	581	1	602	6e-85	292
rs:WP_019079527	DNA topoisomerase III [Yersinia enterocolitica].	31.93	617	369	20	1	581	1	602	6e-85	292
rs:WP_045336155	DNA topoisomerase III [Enterobacter asburiae].	31.69	609	381	15	1	581	1	602	6e-85	292
rs:WP_002091243	DNA topoisomerase III [Bacillus cereus].	33.84	656	381	22	3	627	5	638	6e-85	294
rs:WP_013199786	DNA topoisomerase III [Erwinia billingiae].	30.03	636	407	15	1	611	1	623	6e-85	293
rs:WP_044727511	DNA topoisomerase [Streptococcus pneumoniae].	34.00	597	362	15	1	590	1	572	6e-85	290
rs:WP_024105857	MULTISPECIES: DNA topoisomerase III [Dickeya].	30.48	666	399	22	1	627	1	641	6e-85	292
rs:WP_026706744	DNA topoisomerase III [Flavobacterium frigidarium].	30.28	720	431	22	1	680	1	689	6e-85	295
rs:WP_018919556	DNA topoisomerase III [Prevotella oris].	30.67	701	396	19	1	624	1	688	6e-85	293
rs:WP_000779867	DNA topoisomerase III [Streptococcus agalactiae].	34.00	597	362	15	1	590	1	572	6e-85	290
rs:WP_038203143	DNA topoisomerase III [Xenorhabdus bovienii].	31.35	638	393	14	1	611	1	620	6e-85	293
rs:WP_038904435	DNA topoisomerase III [Dickeya zeae].	31.02	619	372	18	1	581	1	602	6e-85	292
rs:WP_023218679	DNA topoisomerase III [Salmonella enterica].	29.86	663	414	17	1	630	1	645	6e-85	293
rs:WP_032670646	DNA topoisomerase III [Enterobacter cloacae].	31.25	608	389	11	1	587	1	600	6e-85	291
rs:WP_044825433	DNA topoisomerase III [Clostridium aceticum].	32.06	652	398	19	3	627	5	638	6e-85	294
sp:TOP3_STAS1	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	33.39	626	384	14	3	615	4	609	6e-85	294
rs:WP_021510069	DNA topoisomerase III [Pantoea dispersa].	32.52	612	358	19	1	574	1	595	6e-85	292
rs:WP_036027634	DNA topoisomerase III [Brochothrix thermosphacta].	32.62	653	390	16	3	631	4	630	6e-85	294
rs:WP_039693940	DNA topoisomerase III [Dickeya solani].	30.98	665	397	21	1	627	1	641	7e-85	292
rs:WP_014520434	DNA topoisomerase III [Clostridium botulinum].	31.66	676	396	24	3	638	5	654	7e-85	294
rs:WP_045965975	DNA topoisomerase III [Vibrio nigripulchritudo].	32.94	592	357	14	2	560	3	587	7e-85	292
rs:WP_044943098	DNA topoisomerase III [Blautia schinkii].	30.56	697	435	18	1	671	1	674	7e-85	293
rs:WP_036566114	DNA topoisomerase III [Oceanospirillum beijerinckii].	32.48	628	354	18	1	580	1	606	7e-85	292
rs:WP_033569999	DNA topoisomerase III [Dickeya sp. 2B12].	31.02	664	398	22	1	627	1	641	7e-85	292
rs:WP_004248229	DNA topoisomerase III [Proteus mirabilis].	33.66	612	365	17	1	581	1	602	7e-85	292
rs:WP_040000899	DNA topoisomerase III [Dickeya chrysanthemi].	30.48	643	392	17	1	606	1	625	7e-85	292
rs:WP_022600355	DNA topoisomerase III [Vibrio nigripulchritudo].	33.28	592	355	14	2	560	3	587	7e-85	292
rs:WP_014613208	DNA topoisomerase III [Staphylococcus pseudintermedius].	32.59	632	380	18	3	615	5	609	7e-85	293
rs:WP_000366637	MULTISPECIES: DNA topoisomerase [Lactobacillales].	34.28	601	348	15	1	587	1	568	7e-85	290
rs:WP_020061674	DNA topoisomerase III [Bacillus sp. 123MFChir2].	33.28	652	390	21	3	627	5	638	7e-85	294
rs:WP_038925922	DNA topoisomerase III [Dickeya zeae].	31.02	619	372	18	1	581	1	602	8e-85	291
rs:WP_009529996	DNA topoisomerase III [Peptostreptococcaceae bacterium CM5].	36.44	612	326	19	2	595	4	570	8e-85	290
rs:WP_038011289	DNA topoisomerase III, partial [Tannerella sp. oral taxon BU063].	30.45	601	384	14	1	581	1	587	8e-85	290
tr:W0UKE1_YEREN	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.93	617	369	20	1	581	2	603	8e-85	291
rs:WP_031423395	DNA topoisomerase III [Exiguobacterium sp. NG55].	30.42	710	453	17	1	678	1	701	8e-85	293
rs:WP_004390915	DNA topoisomerase III [Yersinia kristensenii].	31.81	613	375	19	1	581	1	602	8e-85	291
rs:WP_033065324	DNA topoisomerase III [Clostridium botulinum].	31.66	676	396	24	3	638	5	654	8e-85	294
rs:WP_022038466	MULTISPECIES: DNA topoisomerase [Clostridiales].	32.52	658	390	21	3	627	4	640	8e-85	294
rs:WP_005366709	DNA topoisomerase III [[Eubacterium] yurii].	35.62	612	325	20	1	583	1	572	8e-85	290
rs:WP_031590979	DNA topoisomerase III [Klebsiella pneumoniae].	31.36	609	387	12	1	587	1	600	8e-85	291
rs:WP_027623839	DNA topoisomerase III [Clostridium lundense].	32.67	652	394	19	3	627	5	638	8e-85	294
rs:WP_022309500	DNA topoisomerase III [Prevotella sp. CAG:474].	32.28	604	382	13	1	590	1	591	8e-85	293
rs:WP_044555099	DNA topoisomerase [Streptococcus pyogenes].	33.67	597	364	15	1	590	1	572	8e-85	290
rs:WP_036610710	MULTISPECIES: DNA topoisomerase III [Parabacteroides].	29.90	709	417	19	1	647	1	691	8e-85	293
rs:WP_038908043	DNA topoisomerase III [Dickeya zeae].	31.02	619	372	18	1	581	1	602	9e-85	291
rs:WP_024157020	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	9e-85	292
rs:WP_020680308	DNA topoisomerase III [Marinobacterium rhizophilum].	28.70	669	442	11	1	640	1	663	9e-85	292
rs:WP_022550047	DNA topoisomerase III [Vibrio nigripulchritudo].	33.28	592	355	14	2	560	3	587	9e-85	292
rs:WP_012020800	DNA topoisomerase [Metallosphaera sedula].	28.47	727	424	20	1	681	1	677	9e-85	293
rs:WP_045353661	DNA topoisomerase III [Enterobacter asburiae].	31.69	609	381	15	1	581	1	602	9e-85	291
rs:WP_001129907	DNA topoisomerase III [Bacillus cereus].	33.49	654	386	21	3	627	5	638	9e-85	294
rs:WP_000366636	DNA topoisomerase [Streptococcus agalactiae].	34.11	604	345	15	1	587	1	568	9e-85	290
rs:WP_022607934	DNA topoisomerase III [Vibrio nigripulchritudo].	32.94	592	357	14	2	560	3	587	9e-85	292
rs:WP_032899009	DNA topoisomerase III [Yersinia bercovieri].	31.12	633	385	20	1	597	1	618	9e-85	291
rs:WP_042859776	DNA topoisomerase III [Dickeya sp. NCPPB 3274].	31.72	618	369	19	1	581	1	602	9e-85	291
rs:WP_002979405	DNA topoisomerase [Chryseobacterium gleum].	32.24	701	420	23	1	673	1	674	9e-85	293
rs:WP_032754074	DNA topoisomerase III [Klebsiella pneumoniae].	32.52	615	368	18	1	581	1	602	9e-85	291
rs:WP_028282183	DNA topoisomerase III [Olleya marilimosa].	31.38	717	422	22	1	676	1	688	9e-85	295
rs:WP_026771933	DNA topoisomerase III [Sediminibacillus halophilus].	31.94	648	400	18	3	626	5	635	9e-85	293
gpu:CP011591_1167	DNA topoisomerase III [Enterobacter asburiae]	31.69	609	381	15	1	581	1	602	9e-85	291
rs:WP_027642634	DNA topoisomerase III [[Clostridium] clostridioforme].	30.56	697	435	18	1	671	1	674	9e-85	293
rs:WP_035131896	DNA topoisomerase III [Clostridium sulfidigenes].	31.23	650	405	16	3	627	5	637	9e-85	294
rs:WP_038261253	DNA topoisomerase III [[Clostridium] litorale].	31.60	652	400	18	3	627	5	637	9e-85	293
rs:WP_039266154	DNA topoisomerase III [Enterobacter sp. FB].	31.69	609	381	15	1	581	1	602	1e-84	291
rs:WP_010243805	DNA topoisomerase III [Acetivibrio cellulolyticus].	32.46	650	396	19	3	627	5	636	1e-84	293
rs:WP_018212069	DNA topoisomerase III [Desulfitobacterium hafniense].	31.90	652	398	17	3	627	5	637	1e-84	293
rs:WP_000779860	DNA topoisomerase III [Streptococcus agalactiae].	34.05	602	348	14	1	587	1	568	1e-84	289
rs:WP_034818146	DNA topoisomerase III [Exiguobacterium alkaliphilum].	30.06	712	455	16	1	678	1	703	1e-84	293
tr:C7X8X1_9PORP	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEU51650.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EEU51650.1};	29.69	704	425	17	1	647	12	702	1e-84	293
rs:WP_022364467	DNA topoisomerase [Clostridium sp. CAG:505].	31.48	664	412	18	3	636	5	655	1e-84	293
rs:WP_008449295	DNA topoisomerase III [Prevotella amnii].	33.28	625	352	19	1	581	1	604	1e-84	291
rs:WP_036883579	DNA topoisomerase III [Porphyromonas gingivicanis].	33.01	612	362	18	1	581	1	595	1e-84	291
rs:WP_009637991	DNA topoisomerase III [Serratia sp. M24T3].	32.57	614	369	20	1	581	1	602	1e-84	291
rs:WP_001618284	DNA topoisomerase III [Salmonella enterica].	32.46	613	371	19	1	581	1	602	1e-84	291
rs:WP_034143173	DNA topoisomerase III [Desulfosporosinus sp. BICA1-9].	31.65	654	400	17	3	627	5	640	1e-84	293
rs:WP_042394020	DNA topoisomerase III [Clostridium sp. JCC].	32.52	658	384	20	3	627	5	635	1e-84	293
rs:WP_002201907	DNA topoisomerase III [Bacillus cereus].	33.99	656	380	23	3	627	5	638	1e-84	293
rs:WP_023311262	DNA topoisomerase III [Enterobacter cloacae].	31.69	609	381	15	1	581	1	602	1e-84	291
rs:WP_004243257	DNA topoisomerase III [Proteus mirabilis].	34.15	615	358	20	1	581	1	602	1e-84	291
rs:WP_041865800	DNA topoisomerase III [Solibacillus silvestris].	32.87	654	389	20	3	627	5	637	1e-84	293
rs:WP_012744292	MULTISPECIES: DNA topoisomerase III [Clostridiales].	31.07	692	433	17	1	671	1	669	1e-84	293
rs:WP_002482608	DNA topoisomerase III [Staphylococcus saprophyticus].	33.39	626	384	14	3	615	4	609	1e-84	293
rs:WP_032681222	DNA topoisomerase III [Enterobacter sp. BIDMC 30].	31.53	609	382	15	1	581	1	602	1e-84	291
rs:WP_036254279	DNA topoisomerase [Methylobacter sp. BBA5.1].	32.31	619	369	16	1	580	1	608	1e-84	292
tr:C4SCV1_YERMO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.12	633	385	20	1	597	2	619	1e-84	291
rs:WP_008774235	DNA topoisomerase III [Bacteroides sp. 2_1_33B].	29.24	701	430	15	1	647	1	689	1e-84	293
tr:F7S991_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.09	668	425	18	1	640	1	654	1e-84	293
tr:C4S6E6_YERBE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.12	633	385	20	1	597	2	619	1e-84	291
rs:WP_039259411	DNA topoisomerase III [Clostridium botulinum].	33.28	661	378	21	3	627	5	638	1e-84	293
rs:WP_032657921	DNA topoisomerase III [Enterobacter sp. DC1].	31.69	609	381	15	1	581	1	602	1e-84	291
rs:WP_044544965	DNA topoisomerase III [Parabacteroides distasonis].	30.10	701	422	18	1	647	1	687	1e-84	293
rs:WP_032814471	DNA topoisomerase III [Yersinia mollaretii].	31.12	633	385	20	1	597	1	618	1e-84	291
rs:WP_023211957	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	1e-84	291
rs:WP_044231725	DNA topoisomerase III [Porphyromonas sp. COT-290 OH3588].	30.17	653	415	18	1	624	1	641	1e-84	292
rs:WP_028527329	DNA topoisomerase III [Ruminococcus gauvreauii].	31.09	669	386	19	3	627	4	641	1e-84	293
rs:WP_008404653	DNA topoisomerase III [Bacillus isronensis].	32.87	654	389	20	3	627	5	637	1e-84	293
rs:WP_018357668	DNA topoisomerase III [Porphyromonas levii].	31.36	609	379	14	1	587	1	592	1e-84	290
rs:WP_025204419	DNA topoisomerase III [Enterobacter cloacae].	31.53	609	382	15	1	581	1	602	1e-84	291
rs:WP_021385145	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.28	658	367	23	3	631	5	619	1e-84	293
rs:WP_002159436	DNA topoisomerase III [Bacillus cereus].	33.49	654	386	21	3	627	5	638	1e-84	293
rs:WP_008791950	DNA topoisomerase III [Coprobacillus sp. 8_2_54BFAA].	28.71	700	452	18	1	679	1	674	1e-84	292
rs:WP_004827735	DNA topoisomerase III [Anaerococcus lactolyticus].	33.44	601	353	13	1	587	1	568	1e-84	289
rs:WP_001140204	DNA topoisomerase III [Bacillus cereus].	33.99	656	380	21	3	627	5	638	1e-84	293
rs:WP_039505489	DNA topoisomerase III [Pectobacterium carotovorum].	32.15	619	365	20	1	581	1	602	1e-84	291
rs:WP_009220366	DNA topoisomerase III [Lachnospiraceae oral taxon 107].	31.60	693	427	19	1	671	1	668	1e-84	292
rs:WP_036854427	DNA topoisomerase III [Prevotella amnii].	33.28	625	352	19	1	581	1	604	1e-84	291
rs:WP_032673185	DNA topoisomerase III [Enterobacter sp. BIDMC 27].	32.19	612	374	18	1	581	1	602	1e-84	291
tr:A0A096LKN5_9ACTN	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.57	735	454	19	3	680	4	724	1e-84	293
rs:WP_020898703	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	1e-84	291
rs:WP_004101300	DNA topoisomerase III [Klebsiella oxytoca].	31.97	638	395	18	1	608	1	629	1e-84	291
rs:WP_012884825	DNA topoisomerase III [Dickeya dadantii].	31.07	618	372	18	1	581	1	601	1e-84	291
rs:WP_017154075	DNA topoisomerase III [Bacillus sp. FJAT-13831].	33.79	654	384	20	3	627	5	638	1e-84	293
rs:WP_001129908	DNA topoisomerase III [Bacillus cereus].	33.49	654	386	21	3	627	5	638	1e-84	293
rs:WP_032910851	DNA topoisomerase III [Yersinia frederiksenii].	31.66	616	372	19	1	581	1	602	1e-84	291
rs:WP_001235860	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	1e-84	291
rs:WP_046457683	DNA topoisomerase III [Hafnia alvei].	32.53	621	360	19	1	581	1	602	1e-84	291
rs:WP_039277542	DNA topoisomerase III [Pectobacterium carotovorum].	31.66	619	368	19	1	581	1	602	1e-84	291
rs:WP_017825375	DNA topoisomerase III, partial [Clostridium botulinum].	32.77	653	392	18	3	627	5	638	1e-84	293
rs:WP_016128273	DNA topoisomerase 3 [Bacillus cereus].	33.49	654	386	21	3	627	5	638	1e-84	293
rs:WP_006174820	DNA topoisomerase III [Enterobacter cancerogenus].	31.69	609	381	15	1	581	1	602	1e-84	291
rs:WP_008456652	DNA topoisomerase III [Enterobacter sp. Ag1].	32.14	613	373	18	1	581	1	602	1e-84	291
rs:WP_018766530	DNA topoisomerase III [Bacillus sp. 105MF].	33.79	654	384	21	3	627	5	638	1e-84	293
rs:WP_026592563	DNA topoisomerase III [Bacillus sp. UNC437CL72CviS29].	33.59	658	380	23	3	627	5	638	1e-84	293
rs:WP_042661428	DNA topoisomerase III [Yersinia enterocolitica].	31.77	617	370	20	1	581	1	602	1e-84	291
rs:WP_014915327	DNA topoisomerase III [Pectobacterium carotovorum].	31.99	619	366	20	1	581	1	602	1e-84	291
rs:WP_005344197	DNA topoisomerase III [[Eubacterium] hallii].	31.07	692	433	17	1	671	1	669	1e-84	292
rs:WP_039489549	DNA topoisomerase III [Pectobacterium carotovorum].	31.99	619	366	20	1	581	1	602	1e-84	291
rs:WP_002592974	DNA topoisomerase III [[Clostridium] clostridioforme].	30.18	709	435	20	1	680	1	678	1e-84	292
rs:WP_039464120	DNA topoisomerase III [Pectobacterium carotovorum].	31.99	619	366	20	1	581	1	602	1e-84	291
tr:F2F8B2_SOLSS	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.87	654	389	20	3	627	8	640	1e-84	293
rs:WP_025328625	DNA topoisomerase III [Aeromonas hydrophila].	30.11	661	401	16	1	624	1	637	1e-84	291
rs:WP_038922734	DNA topoisomerase III [Dickeya dadantii].	31.50	619	369	18	1	581	1	602	1e-84	291
rs:WP_026714869	DNA topoisomerase III [Flavobacterium daejeonense].	30.47	722	419	25	1	676	1	685	1e-84	294
tr:Q1J4U0_STRPF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.67	597	364	15	1	590	5	576	1e-84	289
rs:WP_047061605	DNA topoisomerase III [Enterobacter asburiae].	31.69	609	381	15	1	581	1	602	1e-84	291
rs:WP_019188572	DNA topoisomerase III [Candidatus Prevotella conceptionensis].	32.26	623	390	15	1	605	1	609	1e-84	292
rs:WP_023353350	DNA topoisomerase III [Catonella morbi].	31.60	693	427	19	1	671	1	668	1e-84	292
rs:WP_005680567	DNA topoisomerase I [Bacteroides caccae].	30.94	711	434	22	1	684	1	681	1e-84	292
rs:WP_011816425	DNA topoisomerase III [Yersinia enterocolitica].	31.77	617	370	20	1	581	2	603	1e-84	291
rs:WP_039257876	DNA topoisomerase III [Clostridium botulinum].	33.28	661	378	21	3	627	5	638	1e-84	293
rs:WP_018662197	DNA topoisomerase III [Bacillus acidiproducens].	30.68	665	396	19	3	646	4	624	2e-84	292
rs:WP_005968748	DNA topoisomerase III [Pectobacterium wasabiae].	31.94	620	365	19	1	581	1	602	2e-84	291
gp:CP001837_768	DNA topoisomerase III [Staphylococcus lugdunensis HKU09-01]	33.07	626	385	16	3	615	9	613	2e-84	293
rs:WP_006847775	DNA topoisomerase III [Prevotella copri].	30.40	717	399	19	1	629	1	705	2e-84	293
rs:WP_039544674	DNA topoisomerase III [Pectobacterium carotovorum].	31.99	619	366	20	1	581	1	602	2e-84	291
rs:WP_020283118	DNA topoisomerase III [Yersinia enterocolitica].	31.77	617	370	20	1	581	2	603	2e-84	291
rs:WP_001235876	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	2e-84	291
rs:WP_013842511	DNA topoisomerase III [Desulfotomaculum ruminis].	30.20	702	442	17	3	673	4	688	2e-84	295
rs:WP_038396119	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	2e-84	291
rs:WP_036861766	DNA topoisomerase III [Prevotella bivia].	32.46	613	366	15	1	581	1	597	2e-84	290
rs:WP_033102640	MULTISPECIES: DNA topoisomerase III [Alteromonadales].	32.27	629	377	16	1	596	1	613	2e-84	291
rs:WP_022438027	DNA topoisomerase III [Prevotella sp. CAG:279].	31.00	671	400	22	1	630	1	649	2e-84	292
rs:WP_039514922	DNA topoisomerase III [Pectobacterium carotovorum].	31.99	619	366	20	1	581	1	602	2e-84	291
rs:WP_042545975	DNA topoisomerase III [Yersinia aldovae].	31.93	617	369	20	1	581	1	602	2e-84	291
rs:WP_013464239	MULTISPECIES: DNA topoisomerase III [Pseudoalteromonas].	32.32	628	378	14	1	596	1	613	2e-84	291
rs:WP_001129909	DNA topoisomerase III [Bacillus cereus].	33.49	654	386	21	3	627	5	638	2e-84	293
rs:WP_005166139	DNA topoisomerase III [Yersinia enterocolitica].	31.77	617	370	20	1	581	1	602	2e-84	291
rs:WP_007482184	DNA topoisomerase III [Bacteroides salyersiae].	33.55	608	367	17	1	592	1	587	2e-84	292
rs:WP_023194085	DNA topoisomerase III [Salmonella enterica].	31.51	641	395	20	1	608	1	630	2e-84	291
rs:WP_041083732	DNA topoisomerase III [Clostridium botulinum].	33.08	653	390	19	3	627	5	638	2e-84	293
rs:WP_028834920	MULTISPECIES: DNA topoisomerase III [Pseudoalteromonas].	32.32	628	378	14	1	596	1	613	2e-84	291
rs:WP_037542431	DNA topoisomerase III [Staphylococcus pseudintermedius].	32.44	632	381	17	3	615	5	609	2e-84	292
rs:WP_039286594	DNA topoisomerase III [Pectobacterium carotovorum].	31.99	619	366	20	1	581	1	602	2e-84	291
rs:WP_025150533	DNA topoisomerase III [Bacillus sp. H1a].	33.84	656	381	22	3	627	5	638	2e-84	293
rs:WP_029592603	DNA topoisomerase III [Cronobacter pulveris].	31.07	618	373	17	1	581	1	602	2e-84	291
rs:WP_044177384	DNA topoisomerase III [Enterobacter massiliensis].	32.12	632	377	23	1	597	1	615	2e-84	291
rs:WP_001235868	DNA topoisomerase III [Salmonella enterica].	31.51	641	395	20	1	608	1	630	2e-84	291
rs:WP_001235867	DNA topoisomerase III [Salmonella enterica].	31.51	641	395	20	1	608	1	630	2e-84	291
rs:WP_032495545	DNA processing protein, DNA topoisomerase [uncultured bacterium].	30.78	653	403	16	1	614	1	643	2e-84	292
rs:WP_039511341	DNA topoisomerase III [Pectobacterium carotovorum].	31.99	619	366	20	1	581	1	602	2e-84	291
rs:WP_044271662	DNA topoisomerase III [Candidatus Bacteroides timonensis].	29.50	705	412	16	1	629	1	696	2e-84	292
rs:WP_021909342	DNA topoisomerase III [Prevotella sp. CAG:755].	32.45	604	367	18	1	581	1	586	2e-84	292
rs:WP_017440991	DNA topoisomerase III [Salmonella enterica].	31.51	641	395	20	1	608	1	630	2e-84	291
rs:WP_033557767	DNA topoisomerase [Escherichia coli].	31.79	670	403	16	1	629	1	657	2e-84	291
rs:WP_041729228	DNA topoisomerase III, partial [Desulfovibrio vulgaris].	27.99	686	418	14	3	624	5	678	2e-84	291
tr:C6HTV9_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.00	640	407	13	1	615	1	624	2e-84	291
rs:WP_007374606	DNA topoisomerase III [Kosakonia radicincitans].	32.90	614	367	20	1	581	1	602	2e-84	291
rs:WP_024558046	DNA topoisomerase III [Cronobacter pulveris].	31.07	618	373	17	1	581	1	602	2e-84	291
rs:WP_008813734	DNA topoisomerase III [Hafnia paralvei].	32.69	621	359	19	1	581	1	602	2e-84	290
rs:WP_016266194	DNA topoisomerase III [Yersinia enterocolitica].	31.77	617	370	20	1	581	1	602	2e-84	291
rs:WP_019845046	DNA topoisomerase III [Dickeya zeae].	30.81	620	372	19	1	581	1	602	2e-84	291
rs:WP_001748363	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	2e-84	291
rs:WP_028395884	DNA topoisomerase III [Bacillus sp. FJAT-14578].	33.18	663	376	23	3	627	5	638	2e-84	293
rs:WP_028401311	DNA topoisomerase III [Bacillus panaciterrae].	32.10	651	398	18	3	627	5	637	2e-84	293
tr:F7NDM8_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.28	666	389	22	3	627	5	649	2e-84	292
rs:WP_028309380	DNA topoisomerase III [Desulfitibacter alkalitolerans].	30.17	726	432	22	1	687	1	690	2e-84	292
rs:WP_019035605	DNA topoisomerase III [Prevotella amnii].	33.28	625	352	19	1	581	1	604	2e-84	290
rs:WP_004825718	DNA topoisomerase III [Peptoniphilus lacrimalis].	33.67	597	364	14	1	590	1	572	2e-84	289
sp:TOP3_SALTY	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	31.51	641	395	20	1	608	1	630	2e-84	291
rs:WP_016588639	DNA topoisomerase III, partial [Yersinia pestis].	31.77	617	370	20	1	581	1	602	2e-84	290
rs:WP_023329567	MULTISPECIES: DNA topoisomerase III [Klebsiella].	32.25	645	389	20	1	615	1	627	2e-84	291
rs:WP_035886129	DNA topoisomerase III [Kosakonia radicincitans].	32.90	614	367	20	1	581	1	602	2e-84	291
rs:WP_023481300	DNA topoisomerase III [Enterobacter cloacae].	31.61	639	392	19	1	606	1	627	2e-84	291
rs:WP_001235815	DNA topoisomerase III [Shigella flexneri].	31.42	643	396	19	1	608	1	633	2e-84	291
rs:WP_026949894	DNA topoisomerase III [Alcanivorax sp. 43B_GOM-46m].	30.66	711	428	20	5	670	6	696	2e-84	292
rs:WP_039554976	DNA topoisomerase III [Pectobacterium carotovorum].	31.99	619	366	20	1	581	1	602	2e-84	290
rs:WP_002478828	DNA topoisomerase III [Staphylococcus lugdunensis].	33.07	626	385	16	3	615	4	608	2e-84	292
rs:WP_042782438	DNA topoisomerase III, partial [Salmonella enterica].	32.30	613	372	19	1	581	1	602	2e-84	290
tr:W8UIN6_YEREN	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.93	617	369	20	1	581	1	602	2e-84	290
rs:WP_000366639	DNA topoisomerase [Streptococcus agalactiae].	34.44	601	347	15	1	587	1	568	2e-84	288
rs:WP_034211840	DNA topoisomerase [Lachnoanaerobaculum sp. MSX33].	34.48	583	341	13	1	572	1	553	2e-84	288
rs:WP_034944768	DNA topoisomerase III [Erwinia oleae].	32.42	620	362	20	1	581	1	602	2e-84	290
rs:WP_033145248	DNA topoisomerase III [Enterobacter cloacae].	31.53	609	382	15	1	581	1	602	2e-84	290
rs:WP_001235872	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	2e-84	291
rs:WP_038658888	DNA topoisomerase III [Cedecea neteri].	30.87	664	399	20	1	627	1	641	2e-84	290
rs:WP_038233707	DNA topoisomerase III [Xenorhabdus szentirmaii].	32.36	615	369	17	1	581	1	602	2e-84	290
rs:WP_036872688	DNA topoisomerase I [Porphyromonas macacae].	30.23	698	451	16	1	678	1	682	2e-84	292
rs:WP_039496146	DNA topoisomerase III [Pectobacterium carotovorum].	31.99	619	366	20	1	581	1	602	2e-84	290
rs:WP_031943088	DNA processing protein [uncultured bacterium].	30.78	653	403	16	1	614	1	643	3e-84	291
rs:WP_028896239	DNA topoisomerase I [Prevotella sp. HUN102].	29.24	708	457	16	1	684	1	688	3e-84	292
rs:WP_042839186	DNA topoisomerase III [Yersinia aldovae].	31.93	617	369	20	1	581	1	602	3e-84	290
rs:WP_005933470	DNA topoisomerase III [Bacteroides salyersiae].	33.55	608	367	17	1	592	1	587	3e-84	291
tr:C4U453_YERAL	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.93	617	369	20	1	581	2	603	3e-84	290
rs:WP_044192363	DNA topoisomerase I [Parabacteroides gordonii].	31.44	687	420	19	28	683	9	675	3e-84	292
rs:WP_037536003	DNA topoisomerase III [Staphylococcus haemolyticus].	33.02	639	368	20	3	615	4	608	3e-84	292
rs:WP_044811103	DNA topoisomerase III [Salmonella enterica].	31.51	641	395	20	1	608	1	630	3e-84	290
rs:WP_001235877	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	3e-84	290
rs:WP_001235874	DNA topoisomerase III [Salmonella enterica].	31.51	641	395	20	1	608	1	630	3e-84	290
rs:WP_016408372	DNA topoisomerase III [Firmicutes bacterium CAG:102].	30.15	713	454	19	3	683	5	705	3e-84	292
rs:WP_003068295	DNA topoisomerase [Streptococcus intermedius].	34.11	604	345	16	1	587	1	568	3e-84	288
rs:WP_014069859	DNA topoisomerase III [Enterobacter asburiae].	31.53	609	382	15	1	581	1	602	3e-84	290
tr:A0A078LIC9_CITKO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.31	610	382	16	1	581	1	602	3e-84	290
rs:WP_004634442	DNA topoisomerase III [Gemella morbillorum].	34.18	591	348	13	1	580	1	561	3e-84	288
rs:WP_024292272	MULTISPECIES: DNA topoisomerase III [Lachnoclostridium].	32.37	658	390	20	3	627	4	639	3e-84	293
rs:WP_013779520	DNA topoisomerase III [Tepidanaerobacter acetatoxydans].	32.04	668	380	24	3	627	5	641	3e-84	292
rs:WP_023205568	DNA topoisomerase III [Salmonella enterica].	31.51	641	395	20	1	608	1	630	3e-84	290
rs:WP_023182068	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	3e-84	290
rs:WP_018593291	DNA topoisomerase III [Blautia producta].	28.73	710	421	19	1	683	1	652	3e-84	291
rs:WP_001235862	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	3e-84	290
rs:WP_039121402	DNA topoisomerase [Fusobacterium necrophorum].	33.50	597	365	15	1	590	1	572	3e-84	288
rs:WP_004093052	DNA topoisomerase III [Hafnia alvei].	32.69	621	359	19	1	581	1	602	3e-84	290
rs:WP_044204558	DNA topoisomerase III [Pectobacterium carotovorum].	31.99	619	366	20	1	581	1	602	3e-84	290
tr:C2Z2K2_BACCE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.49	654	386	21	3	627	9	642	3e-84	292
rs:WP_007477853	DNA topoisomerase III [Listeria fleischmannii].	32.51	646	390	19	3	627	5	625	3e-84	292
rs:WP_001235870	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	3e-84	290
rs:WP_001235859	DNA topoisomerase III [Salmonella enterica].	31.51	641	395	20	1	608	1	630	3e-84	290
rs:WP_001235856	DNA topoisomerase III [Salmonella enterica].	31.51	641	395	20	1	608	1	630	3e-84	290
rs:WP_008391092	DNA topoisomerase III [Clostridium sp. SS2/1].	32.22	630	369	18	2	612	3	593	3e-84	291
rs:WP_001235866	DNA topoisomerase III [Salmonella enterica].	31.51	641	395	20	1	608	1	630	3e-84	290
rs:WP_024797455	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	3e-84	290
rs:WP_034130836	DNA topoisomerase III [Peptococcaceae bacterium BICA1-8].	32.77	656	389	19	2	626	4	638	3e-84	292
rs:WP_008754320	DNA topoisomerase [Lachnoanaerobaculum saburreum].	33.61	595	354	13	1	584	1	565	3e-84	288
rs:WP_026677990	DNA topoisomerase III [Fictibacillus gelatini].	31.82	660	396	19	3	646	4	625	3e-84	291
sp:TOP3_STAHJ	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	32.39	633	380	17	3	615	4	608	3e-84	292
rs:WP_010680147	DNA topoisomerase III [Fusobacterium gonidiaformans].	34.00	603	347	14	1	587	1	568	3e-84	288
rs:WP_036659482	DNA topoisomerase III [Paenisporosarcina sp. HGH0030].	32.41	651	392	18	3	627	5	633	3e-84	292
rs:WP_021935895	DNA topoisomerase III [Bacteroides sp. CAG:189].	33.55	608	367	17	1	592	1	587	3e-84	291
rs:WP_039517865	DNA topoisomerase III [Salmonella enterica].	31.51	641	395	20	1	608	1	630	3e-84	290
rs:WP_002174671	DNA topoisomerase III [Bacillus cereus].	33.69	656	382	22	3	627	5	638	3e-84	292
rs:WP_044188831	DNA topoisomerase III [Porphyromonas sp. COT-290 OH860].	30.15	660	419	19	1	630	1	648	3e-84	291
rs:WP_015672564	DNA topoisomerase III [Serratia marcescens].	31.97	613	374	18	1	581	1	602	3e-84	290
rs:WP_001235861	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	3e-84	290
rs:WP_009430769	DNA topoisomerase III [Peptoniphilus sp. oral taxon 375].	33.50	597	365	15	1	590	1	572	3e-84	288
rs:WP_029686830	DNA topoisomerase III [Tatumella saanichensis].	31.83	619	367	21	1	581	1	602	3e-84	290
rs:WP_023610339	DNA topoisomerase III [Streptococcus pyogenes].	33.39	602	352	14	1	587	1	568	3e-84	288
rs:WP_002227932	DNA topoisomerase III [Yersinia pestis].	31.77	617	370	20	1	581	2	603	3e-84	290
rs:WP_043756124	DNA topoisomerase III [Thiorhodococcus sp. AK35].	29.23	732	454	19	1	680	2	721	3e-84	295
rs:WP_023202067	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	3e-84	290
rs:WP_045721498	DNA topoisomerase III, partial [Salmonella enterica].	32.30	613	372	19	1	581	1	602	3e-84	290
tr:J9C5L9_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJW95125.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EJW95125.1};	30.43	713	396	16	1	625	1	701	3e-84	292
rs:WP_002961727	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	32.41	614	369	12	1	579	1	603	3e-84	290
rs:WP_002151617	DNA topoisomerase III [Bacillus cereus].	33.38	656	384	21	3	627	5	638	3e-84	292
rs:WP_042947452	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	3e-84	290
rs:WP_024601516	DNA topoisomerase III [Pseudoalteromonas atlantica].	32.32	628	378	14	1	596	1	613	3e-84	290
rs:WP_022613230	DNA topoisomerase III [Vibrio nigripulchritudo].	33.11	592	356	13	2	560	3	587	3e-84	290
rs:WP_017415049	DNA topoisomerase III [Clostridium tunisiense].	32.52	652	395	20	3	627	5	638	3e-84	292
rs:WP_044349383	DNA topoisomerase III [Raoultella ornithinolytica].	29.86	663	414	17	1	630	1	645	4e-84	291
rs:WP_044909883	DNA topoisomerase III [Lachnospiraceae bacterium MC2017].	30.65	708	432	22	1	673	1	684	4e-84	291
rs:WP_043953786	DNA topoisomerase III [Enterobacter sp. YD4].	32.52	615	368	21	1	581	1	602	4e-84	290
gp:CP007344_1434	DNA topoisomerase III [Salmonella enterica subsp. enterica serovar Enteritidis str.]	32.30	613	372	19	1	581	1	602	4e-84	290
rs:WP_001235873	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	4e-84	290
rs:WP_034915212	DNA topoisomerase III [Erwinia sp. 9145].	32.42	620	362	20	1	581	1	602	4e-84	290
rs:WP_019382435	DNA topoisomerase III [Bacillus oceanisediminis].	33.59	661	377	24	3	627	5	639	4e-84	292
rs:WP_016132338	DNA topoisomerase 3 [Bacillus cereus].	33.79	654	384	21	3	627	5	638	4e-84	292
rs:WP_016079170	DNA topoisomerase 3 [Bacillus cereus].	33.49	654	386	21	3	627	5	638	4e-84	292
sp:TOP3_SALTI	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	32.30	613	372	19	1	581	1	602	4e-84	290
rs:WP_046077495	DNA topoisomerase III [Escherichia fergusonii].	32.35	612	373	18	1	581	1	602	4e-84	290
rs:WP_032467116	DNA topoisomerase III [Yersinia pseudotuberculosis].	31.77	617	370	20	1	581	1	602	4e-84	290
rs:WP_039549510	DNA topoisomerase III [Pectobacterium carotovorum].	31.99	619	366	20	1	581	1	602	4e-84	290
rs:WP_028901949	DNA topoisomerase III [Prevotella corporis].	32.76	644	361	18	1	588	1	628	4e-84	290
rs:WP_039313330	DNA topoisomerase III [Pectobacterium carotovorum].	31.11	614	380	15	1	581	1	604	4e-84	291
rs:WP_038914000	DNA topoisomerase III [Dickeya zeae].	30.97	620	371	19	1	581	1	602	4e-84	290
rs:WP_010295239	DNA topoisomerase III [Pectobacterium carotovorum].	31.99	619	366	20	1	581	1	602	4e-84	290
gp:CP000950_2060	DNA topoisomerase III [Yersinia pseudotuberculosis YPIII]	31.77	617	370	20	1	581	2	603	4e-84	290
rs:WP_016290959	DNA topoisomerase III [Lachnospiraceae bacterium 28-4].	30.25	724	438	21	3	682	4	704	4e-84	291
gpu:CP009997_560	DNA topoisomerase III family protein [Yersinia kristensenii]	31.65	613	376	19	1	581	2	603	4e-84	290
rs:WP_015392895	DNA topoisomerase 3 [Clostridium saccharoperbutylacetonicum].	32.98	658	381	21	3	627	5	635	4e-84	292
rs:WP_016412253	DNA topoisomerase III [Prevotella sp. CAG:1031].	31.45	620	393	14	1	604	1	604	4e-84	289
rs:WP_035294111	DNA topoisomerase III [Clostridium sp. KNHs214].	31.46	658	399	18	3	627	5	643	4e-84	292
rs:WP_012105118	DNA topoisomerase III [Yersinia pseudotuberculosis].	31.77	617	370	20	1	581	1	602	4e-84	290
rs:WP_039315128	DNA topoisomerase III [Pectobacterium carotovorum].	31.99	619	366	20	1	581	1	602	4e-84	290
rs:WP_002211670	DNA topoisomerase III [Yersinia pestis].	31.77	617	370	20	1	581	1	602	4e-84	290
rs:WP_012449561	DNA topoisomerase III [Clostridium botulinum].	32.88	657	387	19	3	627	5	639	4e-84	292
rs:WP_035047422	DNA topoisomerase III [Anoxybacillus sp. KU2-6(11)].	30.54	727	451	20	1	687	1	713	4e-84	291
rs:WP_014826201	DNA topoisomerase III [Desulfosporosinus acidiphilus].	30.88	651	407	16	3	627	5	638	4e-84	292
rs:WP_003002368	DNA topoisomerase [Sphingobacterium spiritivorum].	32.71	700	418	23	1	673	1	674	4e-84	291
rs:WP_001235863	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	4e-84	290
tr:A9N283_SALPB	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.51	641	395	20	1	608	7	636	4e-84	290
rs:WP_029739826	DNA topoisomerase III [Enterobacter asburiae].	31.53	609	382	15	1	581	1	602	4e-84	290
tr:Q57PY5_SALCH	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.51	641	395	20	1	608	20	649	4e-84	290
rs:WP_032536062	MULTISPECIES: DNA topoisomerase I [Bacteroides].	31.06	705	441	21	2	684	8	689	4e-84	291
rs:WP_016911088	hypothetical protein [Staphylococcus vitulinus].	32.27	629	387	14	3	615	4	609	4e-84	291
rs:WP_015957841	DNA topoisomerase III [Clostridium botulinum].	32.30	675	393	24	3	638	5	654	4e-84	292
rs:WP_001235875	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	4e-84	290
rs:WP_038633249	MULTISPECIES: DNA topoisomerase III [Yersinia].	31.65	613	376	19	1	581	1	602	4e-84	290
rs:WP_022737202	DNA topoisomerase III [Laceyella sacchari].	32.31	650	399	19	3	627	5	638	4e-84	292
rs:WP_005805798	DNA topoisomerase I [Bacteroides fragilis].	31.30	706	438	23	2	684	8	689	4e-84	291
gpu:CP010423_2107	DNA topoisomerase III [Pragia fontium]	31.44	617	372	18	1	581	1	602	4e-84	290
rs:WP_004835552	DNA topoisomerase III [Anaerococcus prevotii].	34.00	600	358	16	1	590	1	572	4e-84	288
tr:G5LA33_SALET	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.30	613	372	19	1	581	1	602	5e-84	290
rs:WP_045576535	DNA topoisomerase III, partial [Desulfosporosinus sp. I2].	31.71	656	399	18	3	627	5	642	5e-84	292
rs:WP_016535970	DNA topoisomerase III [Cedecea davisae].	32.14	613	373	18	1	581	1	602	5e-84	290
rs:WP_012769917	MULTISPECIES: DNA topoisomerase III [Dickeya].	30.33	643	393	17	1	606	1	625	5e-84	290
rs:WP_020531862	hypothetical protein [Flexithrix dorotheae].	32.25	710	415	27	1	677	1	677	5e-84	293
rs:WP_040043199	DNA topoisomerase III [Pectobacterium carotovorum].	31.99	619	366	20	1	581	1	602	5e-84	290
rs:WP_045726250	DNA topoisomerase III [Clostridium baratii].	32.72	654	386	20	3	627	4	632	5e-84	291
tr:G5R128_SALSE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.51	641	395	20	1	608	1	630	5e-84	290
rs:WP_023078866	DNA topoisomerase III [Streptococcus pyogenes].	33.67	600	360	16	1	590	1	572	5e-84	288
rs:WP_039262034	MULTISPECIES: DNA topoisomerase III [Enterobacter].	31.53	609	382	15	1	581	1	602	5e-84	290
rs:WP_028513383	DNA topoisomerase III [Ruminococcaceae bacterium AE2021].	30.58	690	428	20	1	664	1	665	5e-84	291
rs:WP_042569714	DNA topoisomerase III [Yersinia intermedia].	31.60	617	371	20	1	581	1	602	5e-84	290
tr:A0A0C5VKB9_9ENTR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.69	621	359	19	1	581	1	602	5e-84	290
rs:WP_046621085	DNA topoisomerase III [Klebsiella pneumoniae].	32.36	615	369	18	1	581	1	602	5e-84	290
rs:WP_039103122	DNA topoisomerase III [Klebsiella variicola].	32.36	615	369	18	1	581	1	602	5e-84	290
rs:WP_023216208	DNA topoisomerase III [Salmonella enterica].	31.51	641	395	20	1	608	1	630	5e-84	290
rs:WP_036936365	DNA topoisomerase III [Proteus vulgaris].	33.50	612	366	17	1	581	1	602	5e-84	290
rs:WP_034735059	DNA topoisomerase I [Chryseobacterium indologenes].	31.97	707	414	24	1	673	1	674	5e-84	291
rs:WP_002169258	DNA topoisomerase III [Bacillus cereus].	33.84	656	381	23	3	627	5	638	5e-84	291
rs:WP_019166616	DNA topoisomerase III [Staphylococcus delphini].	32.32	628	387	16	3	615	5	609	5e-84	291
rs:WP_004856680	DNA topoisomerase III [Klebsiella oxytoca].	29.20	661	421	16	1	630	1	645	5e-84	290
rs:WP_024566642	DNA topoisomerase I [Elizabethkingia anophelis].	32.29	706	413	24	1	673	1	674	5e-84	291
rs:WP_018371562	DNA topoisomerase [Streptococcus massiliensis].	33.89	602	349	14	1	587	1	568	5e-84	287
rs:WP_025903047	MULTISPECIES: DNA topoisomerase III [Tatumella].	33.17	615	364	22	1	581	1	602	5e-84	290
rs:WP_045895139	DNA topoisomerase III [Clostridium botulinum].	32.00	675	395	23	3	638	5	654	6e-84	291
rs:WP_000366635	DNA topoisomerase [Streptococcus agalactiae].	33.72	602	350	14	1	587	1	568	6e-84	287
rs:WP_001235855	DNA topoisomerase III [Salmonella enterica].	31.51	641	395	20	1	608	1	630	6e-84	290
rs:WP_007428825	DNA topoisomerase III [Paenibacillus sp. Aloe-11].	30.88	638	382	18	3	615	4	607	6e-84	291
rs:WP_010287202	DNA topoisomerase III [Kurthia massiliensis].	32.93	656	381	21	3	627	5	632	6e-84	291
rs:WP_000366634	DNA topoisomerase [Streptococcus agalactiae].	33.94	604	346	15	1	587	1	568	6e-84	287
rs:WP_042714821	DNA topoisomerase III [Enterobacter sp. B509].	31.36	609	383	15	1	581	1	602	6e-84	289
rs:WP_047174037	DNA topoisomerase III [Enterobacter cloacae].	31.53	609	382	15	1	581	1	602	6e-84	289
rs:WP_034324734	DNA topoisomerase III [Bacillus sp. DW5-4].	32.97	649	394	20	3	627	5	636	6e-84	291
tr:G5RGI2_SALET	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.30	613	372	19	1	581	1	602	6e-84	290
rs:WP_019192519	DNA topoisomerase [Anaerococcus pacaensis].	33.67	603	356	17	1	590	1	572	6e-84	287
tr:A0A024FL16_9FLAO	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.49	686	407	21	30	676	15	676	6e-84	291
rs:WP_042367709	DNA topoisomerase I [Bacteroidaceae bacterium MS4].	32.16	712	418	24	1	677	1	682	6e-84	291
rs:WP_011013284	TraE protein [uncultured bacterium].	30.47	653	405	16	1	614	1	643	6e-84	290
rs:WP_021015936	DNA topoisomerase III [Serratia sp. ATCC 39006].	31.48	613	377	14	1	581	1	602	6e-84	289
rs:WP_039556869	DNA topoisomerase III [Pectobacterium carotovorum].	31.83	619	367	20	1	581	1	602	6e-84	289
rs:WP_020884435	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	31.36	609	383	15	1	581	1	602	6e-84	289
rs:WP_047348900	DNA topoisomerase III [Enterobacter sp. GN03164].	31.69	609	381	15	1	581	1	602	6e-84	289
tr:D4N0D7_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.22	630	369	18	2	612	3	593	6e-84	291
tr:G8LKH3_ENTCL	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.36	609	383	15	1	581	7	608	6e-84	289
rs:WP_002588924	MULTISPECIES: DNA topoisomerase III [Clostridiales].	30.17	696	437	18	1	670	1	673	6e-84	291
rs:WP_021540324	DNA topoisomerase III [Escherichia coli].	32.19	612	374	18	1	581	1	602	6e-84	290
rs:WP_004911175	DNA topoisomerase III [Providencia rettgeri].	32.48	628	364	20	1	586	1	610	6e-84	289
rs:WP_025802043	DNA topoisomerase III [Hafnia alvei].	32.69	621	359	20	1	581	1	602	7e-84	289
rs:WP_024853195	DNA topoisomerase III [[Ruminococcus] gnavus].	32.52	655	393	20	3	627	4	639	7e-84	291
rs:WP_045401540	DNA topoisomerase III [Enterobacter asburiae].	31.53	609	382	15	1	581	1	602	7e-84	289
rs:WP_017456522	DNA topoisomerase III [Kosakonia sacchari].	32.52	615	368	21	1	581	1	602	7e-84	290
rs:WP_034639106	DNA topoisomerase III [Bacillus manliponensis].	33.89	658	378	23	3	627	5	638	7e-84	291
rs:WP_010348782	DNA topoisomerase III [Paenibacillus peoriae].	31.10	643	374	19	3	615	4	607	7e-84	291
rs:WP_001140199	DNA topoisomerase III [Bacillus cereus].	33.13	655	387	21	3	627	5	638	7e-84	291
rs:WP_007195525	DNA topoisomerase III [Thiocapsa marina].	27.48	757	458	18	3	680	4	748	7e-84	295
rs:WP_008982719	DNA topoisomerase III [Ruminococcaceae bacterium D16].	30.56	648	401	16	1	627	1	620	7e-84	290
rs:WP_010275359	DNA topoisomerase III [Pectobacterium carotovorum].	31.99	619	366	20	1	581	1	602	7e-84	289
rs:WP_032817148	DNA topoisomerase III [Yersinia rohdei].	31.44	617	372	20	1	581	1	602	7e-84	289
rs:WP_040264327	DNA topoisomerase III [Serratia symbiotica].	30.30	670	425	15	1	641	1	657	7e-84	290
rs:WP_008101325	DNA topoisomerase [Verrucomicrobiae bacterium DG1235].	31.64	651	401	17	1	629	1	629	7e-84	293
rs:WP_011948909	DNA topoisomerase III [Clostridium botulinum].	31.50	673	401	21	3	638	5	654	7e-84	291
rs:WP_036153519	DNA topoisomerase III [Lysinibacillus odysseyi].	33.28	655	386	22	3	627	5	638	7e-84	291
tr:A0A0A5N0V8_SERMA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.34	685	435	17	1	649	1	672	7e-84	290
rs:WP_011639937	DNA topoisomerase III [Syntrophomonas wolfei].	30.51	649	407	18	3	626	4	633	7e-84	290
rs:WP_008816171	DNA topoisomerase III [Erysipelotrichaceae bacterium 6_1_45].	30.64	656	407	16	1	636	1	628	7e-84	290
tr:W7DUD1_9LIST	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.99	647	392	18	3	627	5	625	7e-84	290
tr:S2Y1I5_9BACL	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.41	651	392	18	3	627	51	679	7e-84	292
rs:WP_011798734	DNA topoisomerase [Acidovorax sp. JS42].	30.47	653	405	16	1	614	1	643	7e-84	290
rs:WP_007377458	MULTISPECIES: DNA topoisomerase III [Pseudoalteromonas].	32.74	614	367	13	1	579	1	603	7e-84	289
rs:WP_032590617	DNA topoisomerase III [Bacteroides fragilis].	30.67	727	388	23	1	629	1	709	7e-84	291
rs:WP_045892466	DNA topoisomerase III [Clostridium botulinum].	31.46	677	396	23	3	638	5	654	8e-84	291
rs:WP_027712141	DNA topoisomerase III [Dickeya chrysanthemi].	30.33	643	393	17	1	606	1	625	8e-84	289
rs:WP_014903894	DNA topoisomerase III [Desulfosporosinus meridiei].	31.66	657	394	18	3	627	5	638	8e-84	291
rs:WP_035112638	DNA topoisomerase [Finegoldia magna].	33.33	597	366	15	1	590	1	572	8e-84	287
rs:WP_033848526	MULTISPECIES: DNA topoisomerase III [Yersinia].	31.60	617	371	20	1	581	1	602	8e-84	289
rs:WP_019210140	DNA topoisomerase III [Yersinia massiliensis].	31.18	635	382	20	1	597	1	618	8e-84	289
rs:WP_042843630	DNA topoisomerase III [Providencia rettgeri].	32.70	627	364	21	1	586	1	610	8e-84	289
rs:WP_031942999	DNA processing protein [uncultured bacterium].	30.63	653	404	16	1	614	1	643	8e-84	290
rs:WP_046081472	DNA topoisomerase III [Escherichia fergusonii].	31.97	613	374	19	1	581	1	602	8e-84	289
rs:WP_010430094	DNA topoisomerase III [Enterobacter mori].	31.36	609	383	15	1	581	1	602	8e-84	289
rs:WP_028892471	DNA topoisomerase III [Tenacibaculum sp. 47A_GOM-205m].	30.57	736	433	24	1	687	1	707	8e-84	292
rs:WP_038999926	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	8e-84	289
rs:WP_006684866	DNA topoisomerase III [Citrobacter youngae].	32.02	609	379	15	1	581	1	602	8e-84	289
gp:CP007354_1499	DNA topoisomerase III [Salmonella enterica subsp. enterica serovar Enteritidis str.]	32.30	613	372	19	1	581	1	602	9e-84	289
rs:WP_046093421	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	9e-84	289
rs:WP_041160385	DNA topoisomerase [Peptoclostridium difficile].	33.33	597	366	15	1	590	1	572	9e-84	287
rs:WP_035894586	DNA topoisomerase III [Kluyvera ascorbata].	31.87	615	372	20	1	581	1	602	9e-84	289
rs:WP_036963785	DNA topoisomerase III [Providencia alcalifaciens].	32.69	621	359	23	1	581	1	602	9e-84	289
rs:WP_037558586	DNA topoisomerase III [Staphylococcus haemolyticus].	32.39	633	380	17	3	615	4	608	9e-84	291
rs:WP_031565776	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	9e-84	289
rs:WP_043554278	DNA topoisomerase III [Aeromonas bestiarum].	30.21	662	396	19	1	622	1	636	9e-84	289
rs:WP_002113637	DNA topoisomerase III [Bacillus cereus].	33.33	654	387	21	3	627	5	638	9e-84	291
rs:WP_019155274	DNA topoisomerase III [Bacillus massiliosenegalensis].	30.40	658	407	17	3	646	4	624	9e-84	290
rs:WP_024371561	DNA topoisomerase III [Exiguobacterium sp. 8-11-1].	31.23	698	418	20	1	655	1	679	9e-84	290
rs:WP_036975663	DNA topoisomerase III [Providencia alcalifaciens].	32.69	621	359	23	1	581	1	602	9e-84	289
rs:WP_024603571	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	32.41	614	369	12	1	579	1	603	9e-84	289
rs:WP_044159002	DNA topoisomerase III [Enterobacter cloacae].	29.61	662	424	13	1	633	1	649	9e-84	290
rs:WP_016506274	DNA topoisomerase III [Salmonella enterica].	31.36	641	396	20	1	608	1	630	9e-84	289
rs:WP_036965804	DNA topoisomerase III [Providencia alcalifaciens].	32.69	621	359	23	1	581	1	602	9e-84	289
rs:WP_038058568	hypothetical protein, partial [Thermodesulfovibrio islandicus].	33.01	612	353	19	3	577	5	596	1e-83	288
rs:WP_040032912	DNA topoisomerase III [Pectobacterium carotovorum].	31.83	619	367	20	1	581	1	602	1e-83	289
rs:WP_022110771	DNA topoisomerase III [Prevotella sp. CAG:604].	31.32	645	384	15	1	598	1	633	1e-83	291
rs:WP_001235854	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	1e-83	289
rs:WP_036740468	DNA topoisomerase III, partial [Peptostreptococcaceae bacterium oral taxon 113].	31.14	713	430	22	1	683	1	682	1e-83	290
rs:WP_012344773	DNA topoisomerase III [Clostridium botulinum].	31.80	676	395	25	3	638	5	654	1e-83	291
rs:WP_003366695	DNA topoisomerase III [Clostridium botulinum].	32.74	669	370	21	3	627	5	637	1e-83	291
rs:WP_036979414	DNA topoisomerase III [Providencia alcalifaciens].	32.69	621	359	23	1	581	1	602	1e-83	289
rs:WP_023213983	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	1e-83	289
tr:W2CPA6_9PORP	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.67	600	385	15	1	583	1	586	1e-83	287
rs:WP_025434990	DNA topoisomerase III [Eubacterium acidaminophilum].	31.37	714	425	20	1	683	1	680	1e-83	290
rs:WP_025683568	DNA topoisomerase III [Paenibacillus sp. 1-49].	30.61	637	384	17	3	615	4	606	1e-83	290
rs:WP_013184475	DNA topoisomerase III [Xenorhabdus nematophila].	32.41	617	370	18	1	583	1	604	1e-83	288
rs:WP_033032254	DNA topoisomerase III [Pseudoalteromonas citrea].	32.74	614	367	13	1	579	1	603	1e-83	289
tr:C4T5R3_YERIN	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.44	617	372	20	1	581	2	603	1e-83	289
rs:WP_045539505	DNA topoisomerase III [Clostridium botulinum].	31.51	676	403	21	3	641	5	657	1e-83	291
rs:WP_007287723	DNA topoisomerase III [Intestinibacter bartlettii].	33.43	658	365	23	3	631	5	618	1e-83	290
rs:WP_041079115	DNA topoisomerase III [Staphylococcus saprophyticus].	33.23	626	385	14	3	615	4	609	1e-83	290
rs:WP_038220810	DNA topoisomerase III [Xenorhabdus nematophila].	30.46	637	406	13	1	614	1	623	1e-83	289
rs:WP_000779852	DNA topoisomerase III [Streptococcus agalactiae].	33.28	601	354	13	1	587	1	568	1e-83	286
rs:WP_006256849	DNA topoisomerase [Myroides odoratimimus].	32.66	698	419	19	1	673	1	672	1e-83	290
rs:WP_038397646	DNA topoisomerase III [Salmonella enterica].	29.20	661	421	14	1	630	1	645	1e-83	289
rs:WP_023230805	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	1e-83	289
rs:WP_039358423	DNA topoisomerase III [Pectobacterium carotovorum].	31.99	619	366	20	1	581	1	602	1e-83	288
rs:WP_019132809	DNA topoisomerase [Peptoniphilus obesi].	33.84	597	363	15	1	590	1	572	1e-83	287
rs:WP_004841232	DNA topoisomerase III [[Ruminococcus] gnavus].	32.37	658	391	21	3	627	4	640	1e-83	291
rs:WP_025081433	DNA topoisomerase III [Porphyromonas bennonis].	30.66	610	391	14	1	591	1	597	1e-83	290
rs:WP_000838476	DNA topoisomerase III [Staphylococcus aureus].	32.91	629	382	13	3	615	4	608	1e-83	290
rs:WP_040349721	DNA topoisomerase [Anaerococcus tetradius].	33.11	595	370	13	1	590	1	572	1e-83	286
rs:WP_046511331	DNA topoisomerase III [Salinicoccus sp. SV-16].	30.98	652	402	18	3	627	5	635	1e-83	291
tr:M5RIR6_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.66	621	376	18	31	627	8	616	1e-83	290
rs:WP_040551369	DNA topoisomerase [Peptoniphilus duerdenii].	33.50	597	365	15	1	590	1	572	1e-83	286
gp:AE017042_1901	DNA topoisomerase III [Yersinia pestis biovar Microtus str. 91001]	31.77	617	370	20	1	581	2	603	1e-83	288
rs:WP_022591550	DNA topoisomerase III [Vibrio nigripulchritudo].	32.94	592	357	13	2	560	3	587	1e-83	289
rs:WP_015964778	DNA topoisomerase III [Enterobacteriaceae bacterium strain FGI 57].	32.90	614	367	21	1	581	1	602	1e-83	289
rs:WP_015263775	DNA topoisomerase III [Desulfitobacterium dichloroeliminans].	31.90	652	398	17	3	627	5	637	1e-83	291
rs:WP_010181876	DNA topoisomerase III [Aquimarina agarilytica].	30.08	728	428	25	1	676	1	699	1e-83	291
rs:WP_039315510	DNA topoisomerase III [Clostridium baratii].	32.87	654	385	20	3	627	4	632	1e-83	291
rs:WP_039428003	DNA topoisomerase I [Porphyromonas sp. COT-052 OH4946].	30.14	700	453	16	1	680	1	684	1e-83	290
rs:WP_001235881	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	1e-83	289
rs:WP_042317047	DNA topoisomerase III, partial [Desulfotomaculum acetoxidans].	31.53	628	397	12	3	612	5	617	1e-83	290
rs:WP_044739928	DNA topoisomerase III [Bacillus mycoides].	33.33	654	387	21	3	627	5	638	1e-83	291
rs:WP_032734403	DNA topoisomerase III [Klebsiella oxytoca].	31.03	609	389	12	1	587	1	600	1e-83	288
rs:WP_032907590	DNA topoisomerase III [Yersinia intermedia].	31.44	617	372	20	1	581	1	602	1e-83	288
tr:C2CIB3_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.11	595	370	13	1	590	5	576	1e-83	287
rs:WP_003350935	DNA topoisomerase III [Bacillus methanolicus].	30.86	661	401	17	3	646	4	625	1e-83	290
rs:WP_014969939	DNA topoisomerase III [Exiguobacterium antarcticum].	30.18	719	442	23	1	681	1	697	1e-83	290
rs:WP_002230887	DNA topoisomerase III [Yersinia pestis].	31.77	617	370	20	1	581	1	602	1e-83	288
rs:WP_019117236	DNA topoisomerase III [Anaerococcus sp. PH9].	33.50	597	365	15	1	590	1	572	1e-83	286
rs:WP_009245073	DNA topoisomerase III [Lachnospiraceae bacterium 2_1_58FAA].	32.37	658	391	21	3	627	4	640	1e-83	291
rs:WP_002993293	DNA topoisomerase [Sphingobacterium spiritivorum].	32.62	699	420	23	1	673	1	674	1e-83	290
rs:WP_037545408	DNA topoisomerase III [Staphylococcus lugdunensis].	33.07	626	385	16	3	615	4	608	1e-83	290
rs:WP_037376986	DNA topoisomerase, partial [Selenomonas ruminantium].	29.70	660	417	14	1	628	1	645	1e-83	288
rs:WP_008396829	DNA topoisomerase III [Clostridium sp. M62/1].	30.56	648	401	16	1	627	1	620	1e-83	290
rs:WP_010846042	DNA topoisomerase III [Xenorhabdus nematophila].	32.52	615	368	18	1	581	1	602	1e-83	288
rs:WP_045782181	DNA topoisomerase III [Klebsiella michiganensis].	31.97	613	374	18	1	581	1	602	1e-83	289
rs:WP_045481397	DNA topoisomerase III [Bacillus sp. TS-2].	31.74	649	398	21	3	627	5	632	1e-83	290
rs:WP_015364790	DNA topoisomerase III [Staphylococcus warneri].	32.86	633	378	15	3	615	4	609	1e-83	290
rs:WP_032941785	DNA topoisomerase III [Citrobacter sp. 30_2].	31.46	642	396	17	1	608	1	632	1e-83	288
rs:WP_014795822	DNA topoisomerase III [Desulfitobacterium dehalogenans].	31.69	650	402	16	3	627	5	637	1e-83	290
rs:WP_005214016	DNA topoisomerase III [Clostridium celatum].	32.78	659	381	21	3	627	5	635	1e-83	291
rs:WP_024914123	DNA topoisomerase III [Serratia fonticola].	29.82	607	394	11	1	581	1	601	1e-83	289
rs:WP_020586452	DNA topoisomerase III [Desulfobacter curvatus].	29.81	681	433	13	1	654	1	663	1e-83	290
rs:WP_012290743	DNA topoisomerase III [Finegoldia magna].	33.17	597	367	15	1	590	1	572	1e-83	286
rs:WP_005956335	DNA topoisomerase III [Peptoniphilus harei].	33.33	597	366	15	1	590	1	572	1e-83	286
rs:WP_033022586	DNA topoisomerase III [Geobacillus sp. G1w1].	30.55	658	406	16	3	646	4	624	1e-83	290
rs:WP_041890459	DNA topoisomerase I [Myroides profundi].	32.23	698	422	18	1	673	1	672	1e-83	290
rs:WP_038640087	DNA topoisomerase III [Citrobacter freundii].	31.31	642	397	17	1	608	1	632	1e-83	288
rs:WP_023179729	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	1e-83	288
tr:E0NMC4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.50	597	365	15	1	590	5	576	1e-83	286
rs:WP_020189016	DNA topoisomerase III [Kurthia sp. Dielmo].	33.38	656	378	22	3	627	5	632	1e-83	290
rs:WP_047366551	DNA topoisomerase III [Enterobacter sp. GN02226].	31.53	609	386	12	1	587	1	600	1e-83	287
rs:WP_017491015	DNA topoisomerase III [gamma proteobacterium WG36].	32.25	614	371	21	1	581	1	602	1e-83	288
rs:WP_032557817	DNA topoisomerase I [Bacteroides fragilis].	30.80	711	435	22	1	684	1	681	2e-83	290
rs:WP_008537480	DNA topoisomerase III [Megamonas funiformis].	29.96	721	432	17	1	679	1	690	2e-83	290
rs:WP_003010128	DNA topoisomerase [Sphingobacterium spiritivorum].	32.62	699	420	23	1	673	1	674	2e-83	290
rs:WP_004890695	DNA topoisomerase III [Anoxybacillus flavithermus].	29.74	723	462	17	1	687	1	713	2e-83	290
rs:WP_001140201	DNA topoisomerase III [Bacillus cereus].	33.23	659	381	22	3	627	5	638	2e-83	290
rs:WP_017645376	DNA topoisomerase III [Streptococcus agalactiae].	33.39	596	367	13	1	590	1	572	2e-83	286
rs:WP_025074494	DNA topoisomerase III [Bacteroides faecichinchillae].	32.08	639	384	18	1	601	1	627	2e-83	290
rs:WP_038987553	DNA topoisomerase I [Myroides odoratimimus].	33.14	703	410	21	1	673	1	673	2e-83	289
rs:WP_001235880	DNA topoisomerase III [Salmonella enterica].	31.97	613	374	19	1	581	1	602	2e-83	288
rs:WP_038473424	DNA topoisomerase III [Cedecea neteri].	32.14	613	373	18	1	581	1	602	2e-83	289
rs:WP_001235829	DNA topoisomerase III [Escherichia coli].	31.26	643	397	19	1	608	1	633	2e-83	288
rs:WP_039045709	DNA topoisomerase III, partial [Plesiomonas shigelloides].	31.97	610	374	16	1	578	1	601	2e-83	288
rs:WP_044923880	DNA topoisomerase III [Anaerostipes hadrus].	32.38	627	372	18	2	612	3	593	2e-83	290
rs:WP_004331116	DNA topoisomerase III [Porphyromonas asaccharolytica].	32.79	619	357	18	1	581	1	598	2e-83	287
rs:WP_033121899	DNA topoisomerase III [Oscillibacter sp. ER4].	30.44	657	407	17	1	636	1	628	2e-83	289
tr:E6MAJ7_STALU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.75	626	387	16	3	615	9	613	2e-83	290
tr:U2JQH5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.14	713	430	22	1	683	1	682	2e-83	290
rs:WP_000779865	DNA topoisomerase III [Streptococcus agalactiae].	33.33	597	366	15	1	590	1	572	2e-83	286
rs:WP_001405289	DNA topoisomerase 3 [Escherichia coli].	31.06	644	397	20	1	608	1	633	2e-83	288
rs:WP_032934436	DNA topoisomerase III [Citrobacter freundii].	31.46	642	396	17	1	608	1	632	2e-83	288
rs:WP_036770428	DNA topoisomerase III, partial [Plesiomonas shigelloides].	32.24	611	371	18	1	578	1	601	2e-83	288
rs:WP_032947018	DNA topoisomerase III [Citrobacter sp. KTE151].	31.42	643	395	18	1	608	1	632	2e-83	288
rs:WP_031545111	DNA topoisomerase III [Salinicoccus luteus].	31.03	651	404	18	3	627	5	636	2e-83	290
rs:WP_001235878	DNA topoisomerase III [Salmonella enterica].	31.05	641	398	19	1	608	1	630	2e-83	288
rs:WP_037982365	DNA topoisomerase III, partial [Tannerella sp. oral taxon BU063].	30.77	598	383	15	1	581	1	584	2e-83	286
tr:A0A0D6DZW6_9LACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:CEN29530.1};	30.08	718	445	17	3	675	4	709	2e-83	290
rs:WP_044996546	DNA topoisomerase III [Blautia wexlerae].	29.74	696	440	17	2	671	5	677	2e-83	290
rs:WP_001507459	DNA topoisomerase III [Escherichia coli].	31.06	644	397	20	1	608	1	633	2e-83	288
rs:WP_036127568	MULTISPECIES: DNA topoisomerase III [Lysinibacillus].	32.57	651	395	19	3	627	5	637	2e-83	290
rs:WP_021231452	DNA topoisomerase III [Aeromonas veronii].	30.21	652	413	14	1	624	1	638	2e-83	288
rs:WP_029163365	DNA topoisomerase III [Clostridium scatologenes].	31.68	644	384	19	3	615	5	623	2e-83	290
rs:WP_009203344	DNA topoisomerase [Anaerostipes hadrus].	32.59	629	368	19	2	612	3	593	2e-83	290
rs:WP_037543463	DNA topoisomerase III [Staphylococcus lugdunensis].	32.91	626	386	16	3	615	4	608	2e-83	290
rs:WP_040078861	DNA topoisomerase III [Escherichia coli].	31.26	643	397	19	1	608	1	633	2e-83	288
rs:WP_001621484	DNA topoisomerase III [Escherichia coli].	32.19	612	374	18	1	581	1	602	2e-83	288
rs:WP_016103425	DNA topoisomerase 3 [Bacillus cereus].	33.28	658	382	22	3	627	5	638	2e-83	290
rs:WP_006658753	DNA topoisomerase III [Providencia alcalifaciens].	32.69	621	359	23	1	581	1	602	2e-83	288
rs:WP_001235788	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	2e-83	288
rs:WP_039038404	DNA topoisomerase III [Pseudoalteromonas sp. ECSMB14103].	32.95	604	365	15	1	574	1	594	2e-83	288
rs:WP_044647002	DNA topoisomerase III [Paenibacillus terrae].	29.99	677	398	20	3	646	4	637	2e-83	290
rs:WP_039285186	DNA topoisomerase III [Clostridium botulinum].	32.93	665	374	22	3	627	5	637	2e-83	290
rs:WP_026831086	DNA topoisomerase III [Exiguobacterium antarcticum].	30.18	719	442	23	1	681	1	697	2e-83	290
rs:WP_036729935	DNA topoisomerase III, partial [Patulibacter minatonensis].	28.42	732	456	22	3	678	5	724	2e-83	290
rs:WP_006270428	DNA topoisomerase III [Streptococcus constellatus].	35.25	590	335	15	1	576	1	557	2e-83	286
rs:WP_014133159	DNA topoisomerase 3 [Methylomicrobium alcaliphilum].	30.86	661	391	18	1	614	1	642	2e-83	289
tr:G2HD77_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.02	678	422	14	3	626	5	670	2e-83	293
rs:WP_015056502	DNA topoisomerase III [Erwinia amylovora].	29.72	636	409	15	1	611	1	623	2e-83	289
rs:WP_001235849	DNA topoisomerase III [Escherichia albertii].	32.19	612	374	18	1	581	1	602	2e-83	288
tr:A0A077U5P0_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.91	629	382	13	3	615	4	608	2e-83	290
tr:B7LQ29_ESCF3	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.97	613	374	19	1	581	10	611	2e-83	288
rs:WP_006794257	DNA topoisomerase III [Alteromonadales bacterium TW-7].	32.95	604	365	15	1	574	1	594	2e-83	288
rs:WP_036198354	DNA topoisomerase III [Lysinibacillus sinduriensis].	32.98	652	391	20	3	627	5	637	2e-83	290
rs:WP_044157940	DNA topoisomerase III [Salinibacillus aidingensis].	32.08	636	390	16	3	615	5	621	2e-83	290
rs:WP_046275888	DNA topoisomerase III [Citrobacter amalonaticus].	31.31	642	397	17	1	608	1	632	2e-83	288
tr:A0A077VSS3_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.91	629	382	13	3	615	4	608	2e-83	290
tr:A0LAP8_MAGSM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.72	683	420	17	1	630	1	676	2e-83	290
rs:WP_001559227	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	2e-83	288
rs:WP_038154391	DNA topoisomerase III [Trabulsiella guamensis].	32.15	622	371	22	1	584	1	609	2e-83	288
rs:WP_008982250	DNA topoisomerase III [Ruminococcaceae bacterium D16].	30.40	648	402	16	1	627	1	620	2e-83	289
rs:WP_041053511	DNA topoisomerase III [Jeotgalibacillus campisalis].	31.85	650	400	18	3	627	5	636	2e-83	290
rs:WP_001235871	DNA topoisomerase III [Salmonella enterica].	32.14	613	373	19	1	581	1	602	2e-83	288
rs:WP_000765275	DNA topoisomerase III [Escherichia coli].	29.48	658	423	16	1	630	1	645	2e-83	288
rs:WP_045852115	DNA topoisomerase III [Domibacillus enclensis].	33.59	661	376	23	3	627	5	638	2e-83	290
tr:H7E4P1_SALHO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.97	613	374	19	1	581	10	611	2e-83	288
rs:WP_026828856	DNA topoisomerase III [Exiguobacterium sibiricum].	30.06	712	452	22	1	681	1	697	2e-83	289
rs:WP_008132140	DNA topoisomerase III [Pseudoalteromonas sp. BSi20480].	32.95	604	365	15	1	574	1	594	2e-83	288
tr:D6SB76_FINMA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.00	597	368	15	1	590	5	576	2e-83	286
rs:WP_001569929	DNA topoisomerase III [Escherichia coli].	30.64	643	401	19	1	608	1	633	2e-83	288
rs:WP_001235833	DNA topoisomerase III [Escherichia coli].	31.26	643	397	19	1	608	1	633	2e-83	288
rs:WP_047034075	DNA topoisomerase I [Elizabethkingia meningoseptica].	32.68	710	418	23	1	679	1	681	2e-83	289
rs:WP_039058176	DNA topoisomerase III [Enterobacter sp. Bisph1].	32.52	615	368	21	1	581	1	602	2e-83	288
tr:A0A023VCL4_CITFR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.10	643	397	18	1	608	13	644	2e-83	288
rs:WP_009114262	DNA topoisomerase III [Brenneria sp. EniD312].	29.14	683	437	16	1	649	1	670	2e-83	289
rs:WP_045980530	DNA topoisomerase III [Pseudoalteromonas ruthenica].	31.65	613	374	13	1	581	1	600	2e-83	288
rs:WP_007902515	DNA topoisomerase III [Prevotella stercorea].	30.62	712	394	20	1	629	1	695	2e-83	289
rs:WP_023233854	DNA topoisomerase III [Salmonella enterica].	32.30	613	372	19	1	581	1	602	2e-83	288
rs:WP_013185201	DNA topoisomerase III [Xenorhabdus nematophila].	29.84	640	406	13	1	614	1	623	2e-83	288
tr:A9MFG7_SALAR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.97	613	374	19	1	581	1	602	2e-83	288
rs:WP_023055012	DNA topoisomerase III [Peptoniphilus sp. BV3C26].	33.50	597	365	15	1	590	1	572	2e-83	286
rs:WP_039473015	DNA topoisomerase III [Pectobacterium carotovorum].	31.88	618	368	19	1	581	1	602	2e-83	288
rs:WP_001235816	DNA topoisomerase III [Escherichia coli].	31.06	644	397	20	1	608	1	633	2e-83	288
rs:WP_021747342	MULTISPECIES: DNA topoisomerase III [Oscillibacter].	29.68	711	442	19	1	683	1	681	2e-83	289
rs:WP_029516042	DNA topoisomerase III [Paenibacillus polymyxa].	31.39	634	376	18	3	611	4	603	2e-83	290
rs:WP_045511565	DNA topoisomerase III [Kosakonia oryzae].	32.36	615	369	21	1	581	1	602	2e-83	288
tr:R8X2E9_9ENTR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.21	644	395	19	1	608	13	644	3e-83	288
rs:WP_034750165	DNA topoisomerase III [Bacillus wakoensis].	31.28	633	398	18	3	615	5	620	3e-83	290
rs:WP_039292251	DNA topoisomerase III [Cedecea neteri].	31.97	613	374	18	1	581	1	602	3e-83	288
rs:WP_019138735	DNA topoisomerase [Peptoniphilus timonensis].	32.77	595	372	13	1	590	1	572	3e-83	286
rs:WP_024344937	DNA topoisomerase III [[Clostridium] methoxybenzovorans].	32.73	660	385	21	3	627	4	639	3e-83	290
rs:WP_001504346	DNA topoisomerase III [Escherichia coli].	31.26	643	397	19	1	608	1	633	3e-83	288
rs:WP_027384303	DNA topoisomerase I [Chryseobacterium caeni].	32.77	708	407	25	1	673	1	674	3e-83	289
rs:WP_044616212	DNA topoisomerase III [Gynuella sunshinyii].	29.98	637	403	15	1	603	1	628	3e-83	288
rs:WP_008137957	DNA topoisomerase III [Pseudoalteromonas sp. BSi20495].	32.74	614	367	13	1	579	1	603	3e-83	288
rs:WP_008496825	DNA topoisomerase III [Planococcus halocryophilus].	33.99	656	372	24	3	627	4	629	3e-83	290
rs:WP_036145479	DNA topoisomerase III [Lysinibacillus fusiformis].	32.57	651	395	19	3	627	5	637	3e-83	290
rs:WP_019076618	DNA topoisomerase III [Citrobacter sp. KTE32].	31.31	642	397	17	1	608	1	632	3e-83	288
rs:WP_013632654	DNA topoisomerase [Pedobacter saltans].	32.43	700	420	23	1	673	1	674	3e-83	289
gp:CP007371_1649	DNA topoisomerase III [Salmonella enterica subsp. enterica serovar Enteritidis str.]	32.30	613	372	19	1	581	1	602	3e-83	288
rs:WP_004402186	DNA topoisomerase III [Vibrio nigripulchritudo].	32.94	592	357	14	2	560	3	587	3e-83	288
tr:R8ANU3_PLESH	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.24	611	371	18	1	578	1	601	3e-83	288
tr:C8VYF5_DESAS	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.37	628	398	12	3	612	4	616	3e-83	290
rs:WP_022506815	DNA topoisomerase III [Bacteroides sp. CAG:98].	30.34	725	391	22	1	630	19	724	3e-83	290
rs:WP_047199848	DNA topoisomerase [Streptococcus agalactiae].	33.33	597	366	15	1	590	1	572	3e-83	286
rs:WP_046057448	DNA topoisomerase III [Clostridium sp. IBUN62F].	32.75	632	384	16	3	615	5	614	3e-83	290
rs:WP_022927631	DNA topoisomerase III [Patulibacter americanus].	28.81	729	454	23	3	678	5	721	3e-83	291
rs:WP_036956485	DNA topoisomerase III [Providencia alcalifaciens].	32.53	621	360	23	1	581	1	602	3e-83	288
rs:WP_023184966	DNA topoisomerase III [Salmonella enterica].	32.14	613	373	19	1	581	1	602	3e-83	288
rs:WP_010993481	DNA topoisomerase III [Bacteroides fragilis].	30.95	727	386	25	1	629	1	709	3e-83	289
tr:Q66AN9_YERPS	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953}; Flags: Precursor;	31.60	617	371	20	1	581	2	603	3e-83	287
tr:E2ZFS1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.88	621	390	14	68	671	2	606	3e-83	287
rs:WP_035109583	DNA topoisomerase [Finegoldia magna].	33.00	597	368	15	1	590	1	572	3e-83	286
rs:WP_039816568	DNA topoisomerase [Xanthomonas arboricola].	30.90	657	397	19	1	614	1	643	3e-83	288
rs:WP_045969710	DNA topoisomerase III [Xenorhabdus doucetiae].	31.00	642	400	16	1	614	1	627	3e-83	288
rs:WP_039537398	DNA topoisomerase III [Pectobacterium carotovorum].	31.66	616	372	18	1	581	1	602	3e-83	287
rs:WP_032617695	DNA topoisomerase III [Leclercia adecarboxylata].	30.56	602	383	14	1	574	1	595	3e-83	287
rs:WP_002992175	MULTISPECIES: DNA topoisomerase [Myroides].	32.66	698	419	19	1	673	1	672	3e-83	288
rs:WP_014579488	DNA topoisomerase [Marinobacter adhaerens].	31.88	618	372	16	1	580	1	607	3e-83	288
rs:WP_041175458	DNA topoisomerase III [Yersinia pseudotuberculosis].	31.60	617	371	20	1	581	1	602	3e-83	287
rs:WP_035586006	hypothetical protein, partial [Eggerthella lenta].	28.87	710	446	18	3	667	4	699	3e-83	289
rs:WP_007084499	DNA topoisomerase III [Bacillus bataviensis].	33.79	660	376	22	3	627	5	638	3e-83	290
rs:WP_039328218	DNA topoisomerase I [Myroides sp. A21].	32.66	698	419	19	1	673	1	672	3e-83	288
rs:WP_018598357	DNA topoisomerase III [Blautia producta].	31.52	663	395	20	3	627	4	645	3e-83	290
rs:WP_023247999	DNA topoisomerase III [Salmonella enterica].	31.97	613	374	19	1	581	1	602	3e-83	288
rs:WP_007062346	DNA topoisomerase III [Clostridium carboxidivorans].	31.52	644	385	19	3	615	5	623	3e-83	290
rs:WP_022943541	DNA topoisomerase III [Pseudoalteromonas ruthenica].	32.03	615	369	15	1	581	1	600	3e-83	287
tr:X7HRM9_CITFR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.31	642	397	17	1	608	13	644	3e-83	288
rs:WP_001524791	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	3e-83	288
rs:WP_016200501	DNA topoisomerase III [Elizabethkingia meningoseptica].	31.35	705	438	21	1	673	1	691	3e-83	289
rs:WP_002576947	DNA topoisomerase III [[Clostridium] bolteae].	30.43	700	432	19	1	671	1	674	3e-83	289
rs:WP_001140200	DNA topoisomerase III [Bacillus thuringiensis].	33.03	657	385	21	3	627	5	638	3e-83	290
rs:WP_045144547	DNA topoisomerase III [Clostridium butyricum].	32.75	632	384	16	3	615	5	614	3e-83	290
rs:WP_011468024	DNA topoisomerase III [Saccharophagus degradans].	31.84	625	369	17	1	581	1	612	3e-83	287
rs:WP_001548631	DNA topoisomerase III [Escherichia coli].	31.81	613	375	19	1	581	1	602	3e-83	288
rs:WP_001468817	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	3e-83	288
rs:WP_009524905	DNA topoisomerase III [Peptostreptococcaceae bacterium ACC19a].	36.11	612	328	19	2	595	4	570	3e-83	285
rs:WP_001235817	MULTISPECIES: DNA topoisomerase III [Shigella].	30.90	644	398	20	1	608	1	633	4e-83	288
tr:A5Z4Y4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.00	690	425	19	28	683	11	676	4e-83	288
rs:WP_032314111	DNA topoisomerase III [Escherichia coli].	31.20	657	404	20	1	622	1	644	4e-83	287
rs:WP_038020819	DNA topoisomerase III [Tatumella morbirosei].	32.58	617	365	19	1	581	1	602	4e-83	287
rs:WP_043031774	DNA topoisomerase III [Clostridium botulinum].	32.51	692	402	26	3	654	5	671	4e-83	290
rs:WP_024612236	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	31.76	614	373	12	1	579	1	603	4e-83	287
rs:WP_032209748	DNA topoisomerase III [Escherichia coli].	30.90	644	398	20	1	608	1	633	4e-83	288
rs:WP_042078806	DNA topoisomerase III [Aeromonas sanarellii].	30.92	650	379	19	1	604	1	626	4e-83	288
rs:WP_003035804	DNA topoisomerase III [Streptococcus anginosus].	34.81	586	337	15	2	574	4	557	4e-83	285
rs:WP_001235847	DNA topoisomerase III [Escherichia fergusonii].	32.19	612	374	18	1	581	1	602	4e-83	287
rs:WP_005816781	DNA topoisomerase I [Bacteroides fragilis].	30.80	711	435	22	1	684	1	681	4e-83	288
rs:WP_045244221	DNA topoisomerase III [Paenibacillus polymyxa].	30.77	637	376	19	3	611	4	603	4e-83	289
rs:WP_044930428	DNA topoisomerase III [Clostridium sp. M62/1].	30.42	697	436	18	1	671	1	674	4e-83	288
rs:WP_003414618	DNA topoisomerase III [Clostridium butyricum].	32.75	632	384	16	3	615	5	614	4e-83	289
rs:WP_019124129	DNA topoisomerase [Peptoniphilus grossensis].	33.22	596	368	13	1	590	1	572	4e-83	285
rs:WP_001669743	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	4e-83	287
rs:WP_001235776	DNA topoisomerase III [Escherichia coli].	31.42	643	396	19	1	608	1	633	4e-83	287
rs:WP_044712175	DNA topoisomerase III [Citrobacter freundii].	31.31	642	397	17	1	608	1	632	4e-83	287
tr:D4C6M5_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.42	697	436	18	1	671	4	677	4e-83	289
rs:WP_032236924	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	4e-83	287
rs:WP_008777471	DNA topoisomerase I [Bacteroides sp. 2_2_4].	30.04	709	438	20	1	678	1	682	4e-83	288
rs:WP_025264565	DNA topoisomerase III [Thalassolituus oleivorans].	31.60	617	380	15	1	581	1	611	4e-83	288
rs:WP_011304091	DNA topoisomerase III [Sphingomonas sp. A1].	31.16	629	385	15	1	590	1	620	4e-83	288
rs:WP_025892911	DNA topoisomerase I [Bacteroides barnesiae].	30.36	695	437	21	3	673	4	675	4e-83	288
tr:W1U302_CLOBU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.75	632	384	16	3	615	32	641	4e-83	290
rs:WP_046083510	DNA topoisomerase III [Escherichia fergusonii].	32.19	612	374	18	1	581	1	602	4e-83	287
rs:WP_018395581	DNA topoisomerase III [Bacillus sp. 37MA].	33.08	659	382	22	3	627	5	638	4e-83	289
rs:WP_003427476	DNA topoisomerase III [Clostridium butyricum].	32.75	632	384	16	3	615	5	614	4e-83	289
rs:WP_023653786	DNA topoisomerase III [Erwinia piriflorinigrans].	30.21	662	420	13	1	633	1	649	4e-83	288
rs:WP_021531349	DNA topoisomerase III [Escherichia coli].	32.19	612	374	18	1	581	1	602	4e-83	287
rs:WP_029497743	DNA topoisomerase III [Kurthia huakuii].	33.49	657	376	22	3	627	5	632	4e-83	289
rs:WP_044862052	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	4e-83	287
rs:WP_043016627	DNA topoisomerase III [Citrobacter freundii].	31.31	642	397	17	1	608	1	632	4e-83	287
rs:WP_003486940	DNA topoisomerase III [Clostridium sporogenes].	32.59	675	391	25	3	638	5	654	4e-83	289
rs:WP_000779856	DNA topoisomerase III [Streptococcus pneumoniae].	33.95	598	354	14	1	587	1	568	4e-83	285
rs:WP_032576687	DNA topoisomerase I [Bacteroides fragilis].	29.84	707	442	20	1	678	1	682	4e-83	288
rs:WP_007593005	DNA topoisomerase III [Lachnoanaerobaculum sp. OBRC5-5].	29.96	711	440	19	1	683	1	681	4e-83	288
tr:A0A068QQ25_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.06	644	397	17	1	614	7	633	4e-83	288
gp:CP007348_1716	DNA topoisomerase III [Salmonella enterica subsp. enterica serovar Enteritidis str.]	32.14	613	373	19	1	581	1	602	4e-83	287
tr:A0A064E136_CITFR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.10	643	397	18	1	608	13	644	4e-83	288
rs:WP_016099578	DNA topoisomerase III [Bacillus cereus].	31.08	724	431	23	3	680	4	705	4e-83	289
rs:WP_009271940	DNA topoisomerase III [Erysipelotrichaceae bacterium 3_1_53].	31.84	647	398	17	3	625	5	632	4e-83	289
rs:WP_009654423	DNA topoisomerase III [Klebsiella sp. OBRC7].	31.10	611	386	12	1	587	1	600	4e-83	286
rs:WP_039059888	DNA topoisomerase III [Shigella flexneri].	31.26	643	397	19	1	608	1	633	5e-83	287
rs:WP_024597194	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	32.25	614	370	12	1	579	1	603	5e-83	287
rs:WP_031409582	DNA topoisomerase III [Geobacillus vulcani].	30.65	659	404	17	3	646	4	624	5e-83	288
rs:WP_035474305	DNA topoisomerase III [Gammaproteobacteria bacterium MFB021].	29.97	664	416	16	2	630	3	652	5e-83	288
rs:WP_040611578	DNA topoisomerase I [Odoribacter laneus].	30.82	704	439	17	1	678	1	682	5e-83	288
rs:WP_015697218	DNA topoisomerase III [Rahnella aquatilis].	32.68	612	371	18	1	581	1	602	5e-83	287
rs:WP_005680447	DNA topoisomerase I [Bacteroides caccae].	30.18	709	437	20	1	678	1	682	5e-83	288
rs:WP_006255133	DNA topoisomerase III [Alloprevotella tannerae].	30.71	674	412	18	1	630	1	663	5e-83	288
gp:HF952106_658	DNA topoisomerase III [Streptococcus agalactiae ILRI112]	33.22	596	368	13	1	590	1	572	5e-83	285
rs:WP_016236697	DNA topoisomerase III [Escherichia coli].	30.90	644	398	20	1	608	1	633	5e-83	287
rs:WP_040089757	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	5e-83	287
rs:WP_002466483	DNA topoisomerase III [Staphylococcus warneri].	32.70	633	379	15	3	615	4	609	5e-83	289
rs:WP_034599166	DNA topoisomerase III [Desulfosporosinus sp. HMP52].	31.86	656	394	18	3	627	5	638	5e-83	289
rs:WP_001529235	DNA topoisomerase III [Escherichia coli].	32.19	612	374	18	1	581	1	602	5e-83	287
rs:WP_035326368	DNA topoisomerase III [Bacillus firmus].	29.79	678	408	19	3	654	4	639	5e-83	288
rs:WP_009218765	DNA topoisomerase III [Lachnospiraceae oral taxon 107].	34.42	584	340	14	1	572	1	553	5e-83	285
rs:WP_001702636	DNA topoisomerase 3 [Escherichia coli].	30.90	644	398	20	1	608	1	633	5e-83	287
rs:WP_039421179	DNA topoisomerase I [Porphyromonas gulae].	30.90	725	432	24	1	684	1	697	5e-83	288
tr:H1DE94_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EHP49991.1};	30.82	704	439	17	1	678	3	684	5e-83	288
rs:WP_017781182	DNA topoisomerase III [Aeromonas hydrophila].	30.37	652	411	16	1	624	1	637	5e-83	287
rs:WP_001592093	DNA topoisomerase III [Escherichia coli].	31.81	613	375	19	1	581	1	602	5e-83	287
rs:WP_039417014	DNA topoisomerase I [Porphyromonas gingivalis].	29.76	699	454	16	1	678	1	683	5e-83	288
rs:WP_002576342	MULTISPECIES: DNA topoisomerase III [Lachnospiraceae].	29.12	697	445	17	1	671	1	674	5e-83	288
rs:WP_002978178	DNA topoisomerase [Chryseobacterium gleum].	31.80	717	427	22	1	681	1	691	5e-83	288
rs:WP_022387855	DNA topoisomerase [Ruminococcus obeum CAG:39].	31.35	657	397	18	3	627	4	638	5e-83	289
rs:WP_009413679	DNA topoisomerase [Capnocytophaga sp. oral taxon 326].	30.77	728	425	24	1	675	1	702	5e-83	289
rs:WP_035622801	DNA topoisomerase [Hydrogenophaga intermedia].	30.78	653	403	16	1	614	1	643	5e-83	288
rs:WP_033885626	DNA topoisomerase 3 [Escherichia coli].	31.26	643	397	19	1	608	1	633	5e-83	287
rs:WP_044696303	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	5e-83	287
rs:WP_044209346	DNA topoisomerase III [Pectobacterium carotovorum].	30.51	613	385	14	1	581	1	604	5e-83	288
rs:WP_001524338	DNA topoisomerase III [Salmonella enterica].	31.48	610	381	16	1	581	1	602	5e-83	287
rs:WP_005790880	DNA topoisomerase III [Bacteroides fragilis].	30.95	727	386	25	1	629	1	709	5e-83	288
rs:WP_011093894	DNA topoisomerase III [Pectobacterium atrosepticum].	31.94	620	365	20	1	581	1	602	5e-83	287
rs:WP_000779851	DNA topoisomerase III [Streptococcus agalactiae].	33.78	601	351	13	1	587	1	568	6e-83	285
rs:WP_008929975	DNA topoisomerase [Alcanivorax hongdengensis].	31.16	674	408	19	1	629	1	663	6e-83	288
rs:WP_024728265	MULTISPECIES: DNA topoisomerase III [unclassified Clostridiales (miscellaneous)].	31.36	692	431	17	1	671	1	669	6e-83	288
rs:WP_031787084	DNA topoisomerase III [Staphylococcus aureus].	32.91	629	382	13	3	615	4	608	6e-83	288
rs:WP_032936119	DNA topoisomerase III [Escherichia coli].	31.31	642	397	17	1	608	1	632	6e-83	287
rs:WP_042203675	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	6e-83	287
rs:WP_038625843	DNA topoisomerase III [Pantoea sp. PSNIH2].	32.63	619	362	20	1	581	1	602	6e-83	286
rs:WP_021993625	DNA topoisomerase III [Prevotella sp. CAG:487].	29.97	694	400	19	1	629	1	673	6e-83	288
rs:WP_036729055	DNA topoisomerase III [Peptoniphilus sp. ChDC B134].	32.61	641	376	19	2	615	4	615	6e-83	289
rs:WP_041028603	DNA topoisomerase III, partial [Salmonella enterica].	32.23	602	365	19	1	570	1	591	6e-83	285
rs:WP_025745153	DNA topoisomerase III [Shigella flexneri].	31.26	643	397	19	1	608	1	633	6e-83	287
rs:WP_001616960	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	6e-83	287
rs:WP_022219532	DNA topoisomerase III [Bacteroides clarus CAG:160].	30.04	729	384	20	1	625	1	707	6e-83	288
rs:WP_032943124	DNA topoisomerase III [Citrobacter freundii].	31.31	642	397	17	1	608	1	632	6e-83	287
rs:WP_002580164	DNA topoisomerase III [Clostridium butyricum].	32.59	632	385	16	3	615	5	614	6e-83	289
rs:WP_001235813	DNA topoisomerase III [Shigella flexneri].	31.06	644	397	20	1	608	1	633	6e-83	287
rs:WP_039487073	DNA topoisomerase III [Pectobacterium carotovorum].	31.66	619	368	20	1	581	1	602	6e-83	286
rs:WP_006322602	DNA topoisomerase III [Serratia plymuthica].	32.13	610	377	17	1	581	1	602	6e-83	286
rs:WP_020999685	DNA topoisomerase III [Streptococcus anginosus].	34.81	586	337	15	2	574	4	557	6e-83	285
rs:WP_029468332	DNA topoisomerase III [Clostridiales bacterium VE202-06].	31.52	663	395	20	3	627	4	645	6e-83	289
rs:WP_036166771	DNA topoisomerase III, partial [Lysinibacillus sphaericus].	32.82	652	392	20	3	627	5	637	6e-83	288
rs:WP_032181066	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	6e-83	287
rs:WP_028898264	DNA topoisomerase III [Prevotella sp. HUN102].	32.07	633	366	16	1	581	1	621	6e-83	286
rs:WP_022168149	DNA topoisomerase III [Clostridium sp. CAG:221].	32.07	658	387	21	3	627	5	635	6e-83	289
rs:WP_003030667	MULTISPECIES: DNA topoisomerase III [Citrobacter].	31.31	642	397	17	1	608	1	632	6e-83	287
rs:WP_007210360	DNA topoisomerase III [Bacteroides cellulosilyticus].	30.62	650	394	14	1	602	1	641	6e-83	289
rs:WP_017426164	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	30.77	637	376	19	3	611	4	603	6e-83	288
rs:WP_023155789	DNA topoisomerase III [Escherichia coli].	30.87	609	390	12	1	587	1	600	6e-83	286
gp:CP007434_1573	DNA topoisomerase III [Salmonella enterica subsp. enterica serovar Enteritidis str.]	31.86	612	376	18	1	581	1	602	6e-83	287
rs:WP_001235803	DNA topoisomerase 3 [Escherichia coli].	31.06	644	397	20	1	608	1	633	6e-83	287
rs:WP_001235779	DNA topoisomerase 3 [Escherichia coli].	31.10	643	398	19	1	608	1	633	6e-83	287
rs:WP_001235785	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	6e-83	287
rs:WP_029429174	DNA topoisomerase III [Bacteroides cellulosilyticus].	30.62	650	394	14	1	602	1	641	6e-83	289
rs:WP_001235820	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	6e-83	287
rs:WP_032331693	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	6e-83	287
rs:WP_039295725	DNA topoisomerase III [Pectobacterium atrosepticum].	31.83	619	367	20	1	581	1	602	6e-83	286
tr:A0A077V8F9_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.91	629	382	13	3	615	4	608	6e-83	288
rs:WP_037571267	DNA topoisomerase III [Staphylococcus aureus].	32.23	633	381	17	3	615	4	608	6e-83	288
rs:WP_021549854	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	7e-83	287
rs:WP_001728503	DNA topoisomerase III [Salmonella enterica].	30.92	608	391	12	1	587	1	600	7e-83	286
tr:I6HGX2_SHIFL	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.86	609	380	15	1	581	1	602	7e-83	287
rs:WP_001760094	DNA topoisomerase III [Escherichia coli].	30.90	644	398	20	1	608	1	633	7e-83	287
rs:WP_001373800	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	7e-83	287
rs:WP_032568947	DNA topoisomerase III [Bacteroides fragilis].	30.95	727	386	25	1	629	1	709	7e-83	288
rs:WP_024704803	DNA topoisomerase III, partial [Escherichia coli].	31.81	613	375	19	1	581	1	602	7e-83	286
rs:WP_031592267	DNA topoisomerase III [Pantoea agglomerans].	29.72	636	409	15	1	611	1	623	7e-83	288
rs:WP_024232750	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	7e-83	287
rs:WP_001235786	DNA topoisomerase III [Shigella boydii].	31.10	643	398	19	1	608	1	633	7e-83	287
rs:WP_047211613	DNA topoisomerase [Streptococcus agalactiae].	33.17	597	367	14	1	590	1	572	7e-83	285
rs:WP_041895902	DNA topoisomerase III [Clostridium beijerinckii].	33.44	655	382	21	3	627	5	635	7e-83	289
rs:WP_037598662	DNA topoisomerase [Streptococcus sp. AS20].	34.11	601	349	15	1	587	1	568	7e-83	285
rs:WP_033557449	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	7e-83	287
rs:WP_001478208	DNA topoisomerase III [Escherichia coli].	30.90	644	398	20	1	608	1	633	7e-83	287
rs:WP_035196071	DNA topoisomerase III [Bacillus azotoformans].	32.77	656	390	20	3	627	5	640	7e-83	289
rs:WP_042870424	DNA topoisomerase III [Dickeya sp. NCPPB 569].	30.81	620	372	17	1	581	1	602	7e-83	286
rs:WP_044700023	DNA topoisomerase III [Citrobacter freundii].	31.31	642	397	17	1	608	1	632	7e-83	286
rs:WP_027962007	DNA topoisomerase III [Halomonas halodenitrificans].	29.08	643	408	14	1	614	1	624	7e-83	287
rs:WP_032229490	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	7e-83	287
rs:WP_001235819	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	7e-83	287
rs:WP_044954121	DNA topoisomerase III [Faecalibacterium prausnitzii].	30.31	716	445	22	1	683	1	695	7e-83	288
rs:WP_002433736	DNA topoisomerase III [Escherichia hermannii].	31.50	619	369	18	1	581	1	602	7e-83	286
rs:WP_025654210	DNA topoisomerase III [Clostridiales bacterium VE202-21].	29.84	707	447	19	1	683	1	682	7e-83	288
rs:WP_047369938	DNA topoisomerase III [Kluyvera intermedia].	31.08	666	403	23	1	632	1	644	7e-83	286
rs:WP_046596356	DNA topoisomerase III [Salmonella enterica].	31.20	641	397	20	1	608	1	630	7e-83	286
rs:WP_016289059	DNA topoisomerase III [Lachnospiraceae bacterium 3-1].	31.37	644	394	17	3	615	4	630	7e-83	289
tr:C7HSY0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.67	597	364	15	1	590	5	576	7e-83	285
rs:WP_001537001	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	7e-83	287
rs:WP_008657518	MULTISPECIES: DNA topoisomerase III [Bacteroides].	30.95	727	386	25	1	629	1	709	7e-83	288
rs:WP_043865227	DNA topoisomerase III [Enterobacter aerogenes].	31.50	619	369	18	1	581	1	602	7e-83	286
rs:WP_012704744	DNA topoisomerase III [Clostridium botulinum].	32.04	668	404	22	3	638	5	654	7e-83	289
rs:WP_007894717	MULTISPECIES: DNA topoisomerase III [Firmicutes].	33.61	601	352	13	1	587	1	568	7e-83	285
rs:WP_001465398	DNA topoisomerase III [Escherichia coli].	30.95	643	399	19	1	608	1	633	7e-83	287
rs:WP_025383844	DNA topoisomerase III [Yersinia similis].	31.12	617	374	19	1	581	1	602	7e-83	286
rs:WP_035311086	DNA topoisomerase III [Clostridium sp. HMP27].	31.96	654	396	18	3	627	5	638	7e-83	288
rs:WP_015730446	DNA topoisomerase III [Pectobacterium wasabiae].	31.83	619	367	20	1	581	1	602	7e-83	286
rs:WP_001468051	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	7e-83	286
rs:WP_001235795	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	7e-83	286
rs:WP_039300069	DNA topoisomerase III [Pectobacterium betavasculorum].	31.77	620	366	20	1	581	1	602	7e-83	286
rs:WP_042870441	DNA topoisomerase III [Aeromonas piscicola].	30.21	662	396	19	1	622	1	636	7e-83	287
rs:WP_046481302	DNA topoisomerase III [Citrobacter amalonaticus].	30.50	600	387	11	1	578	1	592	7e-83	285
rs:WP_028106718	DNA topoisomerase III [Exiguobacterium undae].	30.03	716	447	23	1	681	1	697	7e-83	288
rs:WP_038988777	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	7e-83	286
sp:TOP3_ECOLI	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	30.90	644	398	20	1	608	1	633	7e-83	286
rs:WP_031418403	DNA topoisomerase III [Lysinibacillus sphaericus].	32.82	652	392	20	3	627	5	637	8e-83	288
rs:WP_045442006	DNA topoisomerase III [Citrobacter sp. S-77].	31.69	609	381	15	1	581	1	602	8e-83	286
rs:WP_033399204	hypothetical protein, partial [Desulfospira joergensenii].	31.75	693	430	21	1	673	1	670	8e-83	289
rs:WP_001235796	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	8e-83	286
rs:WP_045519608	DNA topoisomerase III [Clostridium sporogenes].	32.20	677	391	26	3	638	5	654	8e-83	288
rs:WP_039920388	DNA topoisomerase [Anaerococcus vaginalis].	33.67	597	364	15	1	590	1	572	8e-83	285
rs:WP_005426888	DNA topoisomerase III [[Ruminococcus] obeum].	31.51	657	396	18	3	627	4	638	8e-83	288
rs:WP_001235836	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	8e-83	286
rs:WP_032264420	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	8e-83	286
rs:WP_004308745	MULTISPECIES: DNA topoisomerase I [Bacteroides].	29.76	699	448	20	1	677	1	678	8e-83	288
rs:WP_044231743	DNA topoisomerase I [Porphyromonas sp. COT-290 OH3588].	31.06	718	440	23	1	684	1	697	8e-83	288
rs:WP_018029103	hypothetical protein [Porphyromonas somerae].	31.89	602	375	12	1	581	1	588	8e-83	285
rs:WP_001556646	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	8e-83	286
rs:WP_024933838	DNA topoisomerase III [Clostridium botulinum].	32.04	668	404	22	3	638	5	654	8e-83	288
rs:WP_024564660	MULTISPECIES: DNA topoisomerase I [Elizabethkingia].	31.83	710	429	23	1	682	1	683	8e-83	288
rs:WP_001549282	DNA topoisomerase 3 [Escherichia coli].	30.90	644	398	20	1	608	1	633	8e-83	286
rs:WP_047172050	DNA topoisomerase III [Staphylococcus xylosus].	33.91	634	370	17	3	615	4	609	8e-83	288
rs:WP_044804532	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	8e-83	286
rs:WP_033814661	DNA topoisomerase III [Escherichia coli].	30.90	644	398	20	1	608	1	633	8e-83	286
rs:WP_001235831	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	8e-83	286
rs:WP_032076274	DNA topoisomerase III [Clostridium drakei].	31.68	644	384	19	3	615	5	623	8e-83	288
rs:WP_004584311	DNA topoisomerase [Porphyromonas gingivalis].	30.85	726	431	24	1	684	1	697	8e-83	288
rs:WP_024229705	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	8e-83	286
rs:WP_023154312	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	8e-83	286
rs:WP_033674455	DNA topoisomerase III [Bacillus gaemokensis].	33.54	656	383	21	3	627	5	638	8e-83	288
rs:WP_037399017	MULTISPECIES: DNA topoisomerase III [Serratia].	31.17	616	375	17	1	581	1	602	8e-83	286
rs:WP_013185129	DNA topoisomerase III [Xenorhabdus nematophila].	30.46	637	406	13	1	614	1	623	8e-83	287
rs:WP_024008877	DNA topoisomerase III [Escherichia coli].	31.81	613	375	19	1	581	1	602	8e-83	286
rs:WP_020231706	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	8e-83	286
rs:WP_001682942	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	8e-83	286
rs:WP_027451300	DNA topoisomerase III [Porphyromonas uenonis].	32.25	617	363	19	1	581	1	598	8e-83	285
rs:WP_033867744	DNA topoisomerase III, partial [Escherichia coli].	31.81	613	375	19	1	581	1	602	8e-83	286
rs:WP_026478513	DNA topoisomerase III [Alkaliphilus transvaalensis].	32.42	657	389	21	3	627	5	638	8e-83	288
rs:WP_040233658	DNA topoisomerase III [Citrobacter sp. CIP 55.13].	31.86	609	380	15	1	581	1	602	8e-83	286
rs:WP_033560856	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	8e-83	286
rs:WP_045177124	DNA topoisomerase III [Escherichia coli].	30.90	644	398	20	1	608	1	633	8e-83	286
rs:WP_016245359	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	8e-83	286
rs:WP_025238906	DNA topoisomerase III [Escherichia albertii].	32.19	612	374	18	1	581	1	602	8e-83	286
rs:WP_032573824	DNA topoisomerase III [Bacteroides fragilis].	30.81	727	387	25	1	629	1	709	9e-83	288
rs:WP_001613225	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	9e-83	286
rs:WP_014298129	DNA topoisomerase I [Bacteroides fragilis].	31.29	719	437	25	1	684	1	697	9e-83	288
rs:WP_032218329	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	9e-83	286
rs:WP_032214108	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	9e-83	286
rs:WP_021530492	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	9e-83	286
rs:WP_014967282	DNA topoisomerase III [Gottschalkia acidurici].	31.80	654	397	18	3	627	5	638	9e-83	288
rs:WP_021518430	DNA topoisomerase III [Escherichia coli].	31.81	613	375	19	1	581	1	602	9e-83	286
rs:WP_032238281	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	9e-83	286
rs:WP_002450320	DNA topoisomerase III [Staphylococcus warneri].	33.39	632	376	15	3	615	4	609	9e-83	288
rs:WP_034612451	DNA topoisomerase III [Desulfosporosinus sp. Tol-M].	32.11	654	393	17	3	627	5	636	9e-83	288
rs:WP_001235801	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	9e-83	286
rs:WP_025364046	DNA topoisomerase III [Paenibacillus polymyxa].	30.77	637	376	19	3	611	4	603	9e-83	288
rs:WP_003371547	DNA topoisomerase III [Clostridium botulinum].	32.57	654	393	19	3	627	5	639	9e-83	288
rs:WP_029268270	DNA topoisomerase III [Virgibacillus alimentarius].	32.02	634	391	17	3	615	5	619	9e-83	288
rs:WP_001461041	DNA topoisomerase III [Escherichia coli].	30.95	643	399	19	1	608	1	633	9e-83	286
rs:WP_040102123	DNA topoisomerase III [Paenibacillus polymyxa].	30.24	678	396	20	3	646	4	638	9e-83	288
rs:WP_000779868	DNA topoisomerase III [Streptococcus agalactiae].	33.50	597	365	15	1	590	1	572	9e-83	284
rs:WP_001235814	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	9e-83	286
tr:F7ML35_CLOBO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.73	663	379	21	3	627	5	638	9e-83	288
rs:WP_008978421	DNA topoisomerase III [Erysipelotrichaceae bacterium 5_2_54FAA].	31.65	632	386	17	3	611	4	612	9e-83	288
rs:WP_022629531	DNA topoisomerase III [Bacillus marmarensis].	31.99	647	397	20	3	627	5	630	9e-83	288
rs:WP_001427702	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	9e-83	286
tr:Q0T4X0_SHIF8	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.06	644	397	20	1	608	20	652	1e-82	287
rs:WP_006801223	DNA topoisomerase I [Dysgonomonas gadei].	31.95	698	435	21	1	676	1	680	1e-82	288
rs:WP_010170286	DNA topoisomerase III [Bacillus coahuilensis].	31.63	626	386	16	3	610	4	605	1e-82	288
rs:WP_032593454	DNA topoisomerase III [Bacteroides fragilis].	30.40	727	390	22	1	629	1	709	1e-82	288
rs:WP_029550108	DNA topoisomerase III [Staphylococcus aureus].	33.18	636	371	18	3	615	4	608	1e-82	288
rs:WP_032533840	DNA topoisomerase III [Bacteroides fragilis].	30.95	727	386	25	1	629	1	709	1e-82	288
rs:WP_032141851	DNA topoisomerase III [Escherichia coli].	30.90	644	398	20	1	608	1	633	1e-82	286
rs:WP_042005726	DNA topoisomerase III [Aeromonas dhakensis].	30.18	656	415	16	1	621	1	648	1e-82	286
rs:WP_006253622	DNA topoisomerase III [Mannheimia haemolytica].	30.02	643	406	14	1	614	1	628	1e-82	287
rs:WP_014279833	DNA topoisomerase III [Paenibacillus terrae].	29.99	677	398	20	3	646	4	637	1e-82	288
rs:WP_021535386	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_001587134	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_001515429	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_001357807	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_001544610	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_025210557	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	1e-82	286
rs:WP_026984412	DNA topoisomerase I [Flavobacterium sp. URHB0058].	31.79	711	417	23	1	676	1	678	1e-82	287
rs:WP_011255183	MULTISPECIES: DNA topoisomerase [Burkholderiales].	30.78	653	403	17	1	614	1	643	1e-82	287
rs:WP_001235802	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_024242534	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_033545713	DNA topoisomerase 3 [Escherichia coli].	30.90	644	398	20	1	608	1	633	1e-82	286
rs:WP_019034344	DNA topoisomerase III [Peptoniphilus lacrimalis].	33.67	597	364	15	1	590	1	572	1e-82	284
rs:WP_037986700	DNA topoisomerase III, partial [Tannerella sp. oral taxon BU063].	30.56	602	383	15	1	583	1	586	1e-82	285
rs:WP_001235799	DNA topoisomerase III [Shigella dysenteriae].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_001235808	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_001698540	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	1e-82	286
rs:WP_036162559	DNA topoisomerase III [Lysinibacillus sphaericus].	32.82	652	392	20	3	627	5	637	1e-82	288
rs:WP_024486969	DNA topoisomerase III [Serratia fonticola].	31.80	610	379	16	1	581	1	602	1e-82	286
rs:WP_013843762	DNA topoisomerase III [Desulfotomaculum ruminis].	32.77	650	396	20	3	627	5	638	1e-82	288
rs:WP_024968239	DNA topoisomerase III [Pantoea sp. IMH].	32.47	619	363	20	1	581	1	602	1e-82	286
rs:WP_001235810	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_032171379	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_034633460	DNA topoisomerase III [Bacillus okhensis].	29.86	633	408	17	3	615	5	621	1e-82	288
rs:WP_041851653	DNA topoisomerase III [Enterobacter sp. Bisph2].	31.24	653	393	23	1	619	1	631	1e-82	286
rs:WP_032205278	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_012905567	DNA topoisomerase III [Citrobacter rodentium].	31.81	613	375	19	1	581	1	602	1e-82	286
rs:WP_001235811	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_009345214	DNA topoisomerase III [Peptoniphilus sp. oral taxon 836].	33.33	597	366	15	1	590	1	572	1e-82	284
rs:WP_001696283	DNA topoisomerase III [Escherichia coli].	30.90	644	398	20	1	608	1	633	1e-82	286
rs:WP_039066058	DNA topoisomerase III [Shigella flexneri].	31.06	644	397	20	1	608	1	633	1e-82	286
rs:WP_001235851	DNA topoisomerase III [Escherichia albertii].	32.19	612	374	18	1	581	1	602	1e-82	286
rs:WP_032281001	DNA topoisomerase III [Escherichia coli].	31.81	613	375	19	1	581	1	602	1e-82	286
rs:WP_013185062	DNA topoisomerase III [Xenorhabdus nematophila].	30.46	637	406	13	1	614	1	623	1e-82	286
rs:WP_028386704	DNA topoisomerase [Legionella geestiana].	30.94	669	413	17	1	629	1	660	1e-82	287
rs:WP_042467760	DNA topoisomerase III [Aeromonas salmonicida].	29.43	666	396	17	1	622	1	636	1e-82	286
rs:WP_001743829	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	1e-82	286
rs:WP_034582630	DNA topoisomerase III [Clostridium acetobutylicum].	32.08	667	400	21	3	638	5	649	1e-82	288
rs:WP_038229473	DNA topoisomerase III [Vibrio sp. ER1A].	32.06	627	357	17	2	581	3	607	1e-82	286
tr:F4VG14_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.90	644	398	20	1	608	10	642	1e-82	286
rs:WP_041588598	DNA topoisomerase III, partial [Thalassolituus oleivorans].	31.44	617	381	15	1	581	1	611	1e-82	285
rs:WP_001235804	MULTISPECIES: DNA topoisomerase III [Escherichia].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_001235807	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_026713731	DNA topoisomerase I [Flavobacterium daejeonense].	32.49	711	423	25	1	682	1	683	1e-82	287
rs:WP_042308879	DNA topoisomerase III [Citrobacter werkmanii].	31.15	642	398	17	1	608	1	632	1e-82	286
rs:WP_032949103	DNA topoisomerase III [Citrobacter freundii].	31.86	609	380	15	1	581	1	602	1e-82	286
tr:B1HZX0_LYSSC	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.82	652	392	20	3	627	8	640	1e-82	288
rs:WP_032162751	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	1e-82	286
rs:WP_024169425	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	1e-82	286
rs:WP_001400432	DNA topoisomerase 3 [Escherichia coli].	31.10	643	398	19	1	608	1	633	1e-82	286
rs:WP_044697366	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	1e-82	286
rs:WP_032256164	DNA topoisomerase III [Escherichia coli].	31.92	614	373	20	1	581	1	602	1e-82	286
rs:WP_024249166	DNA topoisomerase III [Shigella sonnei].	31.10	643	398	19	1	608	1	633	1e-82	286
rs:WP_024248223	DNA topoisomerase III [Escherichia coli].	31.70	612	377	17	1	581	1	602	1e-82	286
rs:WP_021542329	DNA topoisomerase III [Escherichia coli].	31.81	613	375	19	1	581	1	602	1e-82	286
rs:WP_001235797	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	1e-82	286
rs:WP_035408996	DNA topoisomerase III [Exiguobacterium sp. RIT341].	29.99	717	446	23	1	681	1	697	1e-82	287
tr:F4V2S6_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.81	613	375	19	1	581	10	611	1e-82	286
rs:WP_001337807	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_017779312	DNA topoisomerase III [Aeromonas hydrophila].	29.88	656	417	15	1	621	1	648	1e-82	286
rs:WP_021181214	DNA topoisomerase III [Serratia fonticola].	31.80	610	379	16	1	581	1	602	1e-82	286
rs:WP_032942259	DNA topoisomerase III [Citrobacter freundii].	30.97	607	388	13	1	585	1	598	1e-82	285
rs:WP_023987041	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	31.46	642	365	20	3	611	4	603	1e-82	288
rs:WP_021738124	DNA topoisomerase [Eubacterium ramulus].	30.62	712	432	22	2	683	3	682	1e-82	287
rs:WP_003846640	DNA topoisomerase III [Citrobacter freundii].	31.86	609	380	15	1	581	1	602	1e-82	286
rs:WP_000779861	DNA topoisomerase III [Streptococcus agalactiae].	33.61	598	363	16	1	590	1	572	1e-82	284
rs:WP_001235791	MULTISPECIES: DNA topoisomerase III [Escherichia].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_033869912	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_014269454	DNA topoisomerase III [Sphaerochaeta pleomorpha].	31.43	649	380	15	2	615	3	621	1e-82	289
rs:WP_021902623	DNA topoisomerase III [Porphyromonas sp. CAG:1061].	31.89	602	375	12	1	581	1	588	1e-82	285
rs:WP_005657222	DNA topoisomerase III [Bacteroides stercoris].	30.67	675	394	19	1	626	1	650	1e-82	288
rs:WP_021515047	DNA topoisomerase III [Escherichia coli].	31.81	613	375	19	1	581	1	602	1e-82	286
rs:WP_001235805	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_039235853	DNA topoisomerase III [Clostridium sp. K25].	32.73	663	379	21	3	627	5	638	1e-82	288
rs:WP_021571873	DNA topoisomerase III [Escherichia coli].	30.90	644	398	20	1	608	1	633	1e-82	286
rs:WP_033548758	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_039931025	DNA topoisomerase [Anaerococcus lactolyticus].	33.50	597	365	15	1	590	1	572	1e-82	284
rs:WP_001235789	DNA topoisomerase 3 [Escherichia coli].	31.10	643	398	19	1	608	1	633	1e-82	286
tr:C2BCS2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.50	597	365	15	1	590	5	576	1e-82	284
rs:WP_010966230	DNA topoisomerase III [Clostridium acetobutylicum].	32.08	667	400	21	3	638	5	649	1e-82	288
rs:WP_001235809	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_013202431	DNA topoisomerase III [Erwinia billingiae].	32.52	618	364	19	1	581	1	602	1e-82	286
rs:WP_044132082	DNA topoisomerase I [Bacteroides fragilis].	30.04	709	438	20	1	678	1	682	1e-82	287
rs:WP_005798157	DNA topoisomerase III [Bacteroides fragilis].	30.95	727	386	25	1	629	1	709	1e-82	288
rs:WP_001235806	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	1e-82	286
rs:WP_019851501	DNA topoisomerase III [Desulfitobacterium sp. PCE1].	31.54	650	403	16	3	627	5	637	1e-82	288
rs:WP_025757480	DNA topoisomerase III [Shigella flexneri].	31.26	643	397	19	1	608	1	633	1e-82	286
rs:WP_014656070	DNA topoisomerase III [Providencia stuartii].	32.46	650	379	22	1	609	1	631	1e-82	286
rs:WP_014299351	DNA topoisomerase III [Bacteroides fragilis].	30.81	727	387	25	1	629	1	709	1e-82	288
rs:WP_001332112	MULTISPECIES: DNA topoisomerase III [Escherichia].	31.81	613	375	19	1	581	1	602	1e-82	286
rs:WP_031462889	DNA topoisomerase III [Paenibacillus polymyxa].	30.77	637	376	19	3	611	4	603	1e-82	287
rs:WP_016661811	DNA topoisomerase III [Bacteroides stercoris].	30.37	675	396	18	1	626	1	650	1e-82	288
rs:WP_025726041	DNA topoisomerase III [Bacteroides sp. 14(A)].	30.15	650	397	13	1	602	1	641	1e-82	288
tr:F4NFA1_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.90	644	398	20	1	608	20	652	1e-82	286
rs:WP_015445012	DNA topoisomerase [Legionella pneumophila].	30.58	667	418	14	1	629	1	660	1e-82	286
rs:WP_032576270	DNA topoisomerase III [Bacteroides fragilis].	30.81	727	387	25	1	629	1	709	1e-82	288
rs:WP_046373372	DNA topoisomerase III [Serratia liquefaciens].	32.25	614	371	20	1	581	1	602	1e-82	286
rs:WP_016819759	DNA topoisomerase III [Paenibacillus polymyxa].	30.77	637	376	19	3	611	4	603	1e-82	287
rs:WP_031942764	DNA topoisomerase III [uncultured bacterium].	30.73	654	401	16	1	614	1	642	1e-82	287
rs:WP_038330896	DNA topoisomerase I [Empedobacter falsenii].	32.20	705	429	21	1	680	1	681	1e-82	287
rs:WP_004444211	DNA topoisomerase III [Clostridium botulinum].	32.73	663	379	21	3	627	5	638	1e-82	288
rs:WP_021574631	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	1e-82	286
rs:WP_005802239	DNA topoisomerase III [Bacteroides fragilis].	30.81	727	387	25	1	629	1	709	1e-82	287
rs:WP_044755911	DNA topoisomerase [Streptococcus suis].	34.72	599	348	15	1	587	1	568	1e-82	283
rs:WP_010775606	DNA topoisomerase III [Enterococcus faecalis].	33.22	602	353	14	1	587	1	568	1e-82	283
rs:WP_026833507	DNA topoisomerase III [Exiguobacterium undae].	30.40	717	443	25	1	681	1	697	1e-82	287
rs:WP_001235793	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	1e-82	286
rs:WP_036218131	DNA topoisomerase III, partial [Lysinibacillus sphaericus].	32.41	651	396	19	3	627	5	637	1e-82	287
rs:WP_042060564	DNA topoisomerase III [Escherichia coli].	31.86	612	376	18	1	581	1	602	1e-82	286
rs:WP_000779853	DNA topoisomerase III [Streptococcus agalactiae].	33.22	602	353	14	1	587	1	568	1e-82	283
rs:WP_046123363	DNA topoisomerase III [Escherichia coli].	30.90	644	398	20	1	608	1	633	1e-82	286
rs:WP_006261870	DNA topoisomerase [Myroides odoratimimus].	30.90	699	438	19	1	676	1	677	1e-82	287
rs:WP_032559152	DNA topoisomerase I [Bacteroides fragilis].	29.76	699	448	20	1	677	1	678	1e-82	287
rs:WP_038340935	DNA topoisomerase 3 [Escherichia coli].	30.90	644	398	20	1	608	1	633	1e-82	286
rs:WP_032224183	DNA topoisomerase III [Escherichia coli].	31.07	647	393	20	1	608	1	633	1e-82	286
rs:WP_001235840	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	1e-82	286
rs:WP_013548841	DNA topoisomerase III [Bacteroides helcogenes].	30.88	651	379	17	1	597	1	634	1e-82	288
rs:WP_001242113	DNA topoisomerase III [Escherichia coli].	28.86	641	416	14	1	614	1	628	2e-82	286
rs:WP_045886111	DNA topoisomerase III [Clostridium sporogenes].	32.35	677	390	26	3	638	5	654	2e-82	288
rs:WP_001602679	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	2e-82	286
rs:WP_018967490	DNA topoisomerase III [Prevotella loescheii].	30.52	688	408	17	1	630	1	676	2e-82	286
rs:WP_003033547	MULTISPECIES: DNA topoisomerase III [Bacteria].	34.05	602	348	14	1	587	1	568	2e-82	283
rs:WP_001235844	DNA topoisomerase 3 [Shigella boydii].	30.95	643	399	19	1	608	1	633	2e-82	286
rs:WP_008769960	DNA topoisomerase III [Bacteroides sp. 2_1_16].	30.81	727	387	25	1	629	1	709	2e-82	287
rs:WP_032563483	DNA topoisomerase III [Bacteroides fragilis].	30.81	727	387	25	1	629	1	709	2e-82	287
rs:WP_032529132	DNA topoisomerase III [Bacteroides fragilis].	30.81	727	387	25	1	629	1	709	2e-82	287
rs:WP_022348346	MULTISPECIES: DNA topoisomerase III [Bacteroides].	30.81	727	387	25	1	629	1	709	2e-82	287
rs:WP_039229157	DNA topoisomerase III [Clostridium haemolyticum].	32.73	663	379	21	3	627	5	638	2e-82	288
rs:WP_029452668	DNA topoisomerase III [Clostridium algidicarnis].	32.29	638	385	19	3	615	5	620	2e-82	288
rs:WP_017785618	DNA topoisomerase III [Aeromonas hydrophila].	30.18	656	415	16	1	621	1	648	2e-82	286
rs:WP_001235830	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	2e-82	286
rs:WP_045756463	DNA topoisomerase I [Sphingobacterium sp. PM2-P1-29].	32.30	712	415	24	1	678	1	679	2e-82	287
rs:WP_016215923	DNA topoisomerase III [Eubacterium sp. 14-2].	31.24	669	393	17	3	627	4	649	2e-82	288
rs:WP_002843661	DNA topoisomerase III [Peptostreptococcus anaerobius].	34.05	602	348	14	1	587	1	568	2e-82	283
rs:WP_003904754	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	2e-82	286
rs:WP_001592585	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	2e-82	286
rs:WP_007364773	DNA topoisomerase III [Porphyromonas uenonis].	32.09	617	364	19	1	581	1	598	2e-82	285
rs:WP_001235787	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	2e-82	286
rs:WP_012602800	DNA topoisomerase III [Escherichia coli].	31.81	613	375	19	1	581	20	621	2e-82	286
rs:WP_045146249	DNA topoisomerase III [Escherichia coli].	28.86	641	416	14	1	614	1	628	2e-82	286
rs:WP_035209415	DNA topoisomerase III [Acidithiobacillus thiooxidans].	31.22	679	401	18	3	640	4	657	2e-82	288
rs:WP_013095152	DNA topoisomerase III [Enterobacter cloacae].	29.62	638	411	11	1	613	1	625	2e-82	287
rs:WP_024209137	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	2e-82	286
rs:WP_032594406	DNA topoisomerase I [Bacteroides fragilis].	30.96	717	426	23	1	684	1	681	2e-82	287
tr:M5DMV3_9GAMM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.44	617	381	15	1	581	1	611	2e-82	286
rs:WP_017842783	DNA topoisomerase [Methylomicrobium buryatense].	30.45	660	395	17	1	614	1	642	2e-82	286
tr:X7I8G3_CITFR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.86	609	380	15	1	581	13	614	2e-82	286
rs:WP_039256074	DNA topoisomerase III [Clostridium novyi].	32.43	663	380	20	3	627	5	637	2e-82	288
tr:F4SYZ0_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.03	612	375	18	1	581	10	611	2e-82	286
tr:B7MVP0_ECO81	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.81	613	375	19	1	581	20	621	2e-82	286
rs:WP_006844208	DNA topoisomerase I [Dysgonomonas mossii].	30.91	702	445	20	1	680	1	684	2e-82	287
rs:WP_024399802	DNA topoisomerase [Streptococcus suis].	34.88	582	334	15	3	571	4	553	2e-82	283
rs:WP_021286089	DNA topoisomerase III [Staphylococcus aureus].	33.18	636	371	18	3	615	4	608	2e-82	287
rs:WP_002461797	DNA topoisomerase III [Staphylococcus simiae].	32.86	636	373	20	3	615	4	608	2e-82	287
rs:WP_011988143	DNA topoisomerase III [Clostridium botulinum].	31.99	669	403	23	3	638	5	654	2e-82	288
rs:WP_032303179	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	2e-82	286
rs:WP_001235852	DNA topoisomerase III [Escherichia coli].	31.65	613	376	19	1	581	1	602	2e-82	286
rs:WP_004945367	DNA topoisomerase III [Serratia plymuthica].	32.24	611	375	18	1	581	1	602	2e-82	285
rs:WP_032180754	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	2e-82	285
rs:WP_032207849	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	2e-82	286
rs:WP_001235777	DNA topoisomerase III [Shigella sonnei].	31.26	643	397	19	1	608	1	633	2e-82	286
tr:W1XDJ4_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	31.86	612	376	18	1	581	1	602	2e-82	285
rs:WP_024239616	DNA topoisomerase III [Escherichia coli].	31.81	613	375	19	1	581	1	602	2e-82	286
rs:WP_034173447	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	2e-82	285
rs:WP_032153052	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	2e-82	286
rs:WP_039025772	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	2e-82	286
rs:WP_001363417	DNA topoisomerase III [Escherichia coli].	31.81	613	375	19	1	581	1	602	2e-82	286
rs:WP_007654023	DNA topoisomerase I [Parabacteroides goldsteinii].	30.80	711	435	22	1	684	1	681	2e-82	286
rs:WP_032323149	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	2e-82	286
rs:WP_002980964	DNA topoisomerase [Chryseobacterium gleum].	32.71	700	423	24	1	673	1	679	2e-82	286
rs:WP_046525659	DNA topoisomerase III [Bacillus sp. SA2-6].	30.26	661	406	17	3	646	4	626	2e-82	286
rs:WP_001235790	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	2e-82	286
rs:WP_024528781	DNA topoisomerase III [Serratia fonticola].	31.80	610	379	16	1	581	1	602	2e-82	285
rs:WP_046870172	DNA topoisomerase III, partial [Clostridium sporogenes].	32.05	677	392	26	3	638	5	654	2e-82	287
rs:WP_001235845	MULTISPECIES: DNA topoisomerase III [Shigella].	31.10	643	398	19	1	608	1	633	2e-82	286
rs:WP_032290511	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	2e-82	285
gp:CP000468_1639	DNA topoisomerase III [Escherichia coli APEC O1]	31.81	613	375	19	1	581	19	620	2e-82	286
rs:WP_017787114	DNA topoisomerase III [Aeromonas hydrophila].	30.02	663	407	18	1	621	1	648	2e-82	286
rs:WP_001235778	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	2e-82	285
rs:WP_001600005	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	2e-82	285
rs:WP_004313263	DNA topoisomerase I [Bacteroides xylanisolvens].	29.80	698	449	19	1	677	1	678	2e-82	286
rs:WP_007705937	DNA topoisomerase III [[Clostridium] asparagiforme].	30.08	708	441	20	2	683	3	682	2e-82	286
rs:WP_032565346	DNA topoisomerase III [Bacteroides fragilis].	30.54	727	389	23	1	629	1	709	2e-82	287
rs:WP_022091491	DNA topoisomerase [Lachnospiraceae bacterium CAG:25].	32.22	627	373	18	2	612	3	593	2e-82	287
rs:WP_013726277	DNA topoisomerase III [Clostridium botulinum].	32.98	661	380	21	3	627	5	638	2e-82	287
rs:WP_032257590	DNA topoisomerase III [Escherichia coli].	30.75	644	399	20	1	608	1	633	2e-82	285
rs:WP_000779863	DNA topoisomerase III [Streptococcus agalactiae].	33.17	597	367	15	1	590	1	572	2e-82	283
gp:CP007439_2807	DNA topoisomerase III [Serratia plymuthica]	32.24	611	375	18	1	581	1	602	2e-82	285
rs:WP_039310260	DNA topoisomerase III [Pectobacterium atrosepticum].	31.94	620	365	20	1	581	1	602	2e-82	285
rs:WP_024216553	DNA topoisomerase III [Escherichia coli].	31.65	613	376	19	1	581	1	602	2e-82	285
rs:WP_001235834	DNA topoisomerase III [Shigella sonnei].	31.10	643	398	19	1	608	1	633	2e-82	285
rs:WP_037033921	DNA topoisomerase III [Rahnella sp. WP5].	32.36	618	365	19	1	581	1	602	2e-82	285
rs:WP_014386463	DNA topoisomerase III [Comamonas testosteroni].	30.78	653	403	17	1	614	1	643	2e-82	287
rs:WP_006812878	DNA topoisomerase III [Providencia rustigianii].	32.58	623	357	23	1	581	1	602	2e-82	285
rs:WP_032201055	DNA topoisomerase III [Escherichia coli].	30.90	644	398	20	1	608	1	633	2e-82	285
rs:WP_039302172	DNA topoisomerase III [Cedecea neteri].	31.97	613	374	18	1	581	1	602	2e-82	286
rs:WP_039272353	DNA topoisomerase III [Paenibacillus polymyxa].	31.07	634	378	18	3	611	4	603	2e-82	287
rs:WP_007218955	DNA topoisomerase III [Bacteroides cellulosilyticus].	30.15	650	397	13	1	602	1	641	2e-82	287
rs:WP_001610217	DNA topoisomerase III [Escherichia coli].	30.90	644	398	20	1	608	1	633	2e-82	285
rs:WP_001479370	DNA topoisomerase III [Escherichia coli].	31.06	644	397	20	1	608	1	633	2e-82	285
rs:WP_012145443	MULTISPECIES: DNA topoisomerase III [Serratia].	31.91	611	377	18	1	581	1	602	2e-82	285
rs:WP_019118541	DNA topoisomerase III [Anaerococcus obesiensis].	33.17	597	367	15	1	590	1	572	2e-82	283
rs:WP_003490483	MULTISPECIES: DNA topoisomerase III [Clostridium].	32.05	677	392	26	3	638	5	654	2e-82	287
rs:WP_032325498	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	2e-82	285
rs:WP_037549759	DNA topoisomerase III [Staphylococcus haemolyticus].	32.71	639	370	20	3	615	4	608	2e-82	287
rs:WP_001235780	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	2e-82	285
rs:WP_001235818	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	2e-82	285
rs:WP_032945967	DNA topoisomerase I [Bacteroides vulgatus].	30.88	706	436	20	1	678	1	682	2e-82	286
rs:WP_032581749	DNA topoisomerase III [Bacteroides fragilis].	30.81	727	387	25	1	629	1	709	2e-82	287
rs:WP_038283351	DNA topoisomerase III [[Clostridium] celerecrescens].	31.37	663	390	19	3	627	4	639	2e-82	287
rs:WP_009222685	DNA topoisomerase III [Peptoniphilus sp. oral taxon 386].	32.28	635	386	17	2	615	4	615	2e-82	287
tr:A0A077U2I5_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.59	629	384	13	3	615	4	608	2e-82	287
rs:WP_005790822	MULTISPECIES: DNA topoisomerase I [Bacteroidetes].	30.94	711	433	23	1	684	1	680	2e-82	286
rs:WP_001403074	DNA topoisomerase 3 [Escherichia coli].	30.95	643	399	19	1	608	1	633	2e-82	285
rs:WP_001235842	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	2e-82	285
rs:WP_001235832	DNA topoisomerase III [Escherichia coli].	30.90	644	398	20	1	608	1	633	2e-82	285
rs:WP_017161576	hypothetical protein [Xanthomonas axonopodis].	27.98	679	434	21	1	639	1	664	3e-82	287
rs:WP_032358600	DNA topoisomerase 3 [Escherichia coli].	30.95	643	399	19	1	608	1	633	3e-82	285
rs:WP_044864258	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	3e-82	285
rs:WP_014219927	DNA topoisomerase III [Niastella koreensis].	30.65	721	433	21	1	675	1	700	3e-82	286
rs:WP_022213677	DNA topoisomerase [Blautia sp. CAG:237].	31.87	659	392	20	3	627	4	639	3e-82	287
rs:WP_036966356	DNA topoisomerase III [Pseudoalteromonas lipolytica].	31.97	610	377	11	1	581	1	601	3e-82	285
rs:WP_032948782	DNA topoisomerase I [Bacteroides vulgatus].	30.88	706	436	20	1	678	1	682	3e-82	286
rs:WP_008911016	DNA topoisomerase III [Providencia burhodogranariea].	32.91	629	360	23	1	586	1	610	3e-82	285
rs:WP_001235794	DNA topoisomerase III [Shigella dysenteriae].	32.03	612	375	18	1	581	1	602	3e-82	285
rs:WP_009323494	DNA topoisomerase III [Subdoligranulum sp. 4_3_54A2FAA].	30.09	648	404	16	1	627	1	620	3e-82	286
rs:WP_033559292	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	3e-82	285
rs:WP_035386680	DNA topoisomerase III, partial [Exiguobacterium sp. S17].	30.74	680	429	18	1	647	1	671	3e-82	286
rs:WP_031574346	DNA topoisomerase III [Proteiniclasticum ruminis].	32.57	654	380	18	3	627	5	626	3e-82	287
rs:WP_001538825	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	3e-82	285
rs:WP_037440394	DNA topoisomerase III, partial [Shewanella sp. YQH10].	30.05	659	410	14	1	622	1	645	3e-82	285
rs:WP_024551811	DNA topoisomerase III [Cronobacter helveticus].	30.71	622	370	20	1	581	1	602	3e-82	285
rs:WP_024942122	DNA topoisomerase III [Aeromonas hydrophila].	30.21	652	412	16	1	624	1	637	3e-82	285
rs:WP_042722218	DNA topoisomerase III, partial [Flavobacterium sp. B17].	33.50	609	356	17	1	583	1	586	3e-82	284
rs:WP_008430415	DNA topoisomerase III [Planococcus donghaensis].	33.69	656	374	24	3	627	4	629	3e-82	287
rs:WP_001235827	MULTISPECIES: DNA topoisomerase III [Escherichia].	32.14	613	373	19	1	581	1	602	3e-82	285
rs:WP_010647795	DNA topoisomerase III [Oceanobacillus massiliensis].	31.85	653	399	20	4	631	6	637	3e-82	287
rs:WP_007896555	DNA topoisomerase III [Streptococcus pseudoporcinus].	33.44	601	353	13	1	587	1	568	3e-82	283
rs:WP_015045035	DNA topoisomerase III [Dehalobacter sp. CF].	30.06	712	437	18	1	683	1	680	3e-82	286
rs:WP_032179590	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	3e-82	285
rs:WP_002843605	DNA topoisomerase III [Peptostreptococcus anaerobius].	33.06	602	354	14	1	587	1	568	3e-82	283
rs:WP_013813220	MULTISPECIES: DNA topoisomerase III [Serratia].	32.24	611	375	18	1	581	1	602	3e-82	285
rs:WP_042907580	DNA topoisomerase III [Gallibacterium anatis].	31.10	627	371	16	1	581	1	612	3e-82	285
rs:WP_046175909	hypothetical protein [Domibacillus indicus].	29.13	714	466	16	1	683	1	705	3e-82	286
rs:WP_005318526	DNA topoisomerase III [Aeromonas salmonicida].	29.43	666	396	17	1	622	1	636	3e-82	285
rs:WP_046885891	DNA topoisomerase III [Enterobacter cloacae].	31.80	654	395	21	1	622	1	635	3e-82	285
rs:WP_005802302	DNA topoisomerase I [Bacteroides fragilis].	30.66	711	436	22	1	684	1	681	3e-82	286
rs:WP_017644362	DNA topoisomerase III [Streptococcus agalactiae].	33.17	597	367	15	1	590	1	572	3e-82	283
tr:C8WNM4_EGGLE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.00	738	447	21	3	680	4	724	3e-82	287
rs:WP_011600633	DNA topoisomerase [Hydrogenophaga intermedia].	30.92	650	405	15	1	614	1	642	3e-82	286
rs:WP_042003754	DNA topoisomerase III [Escherichia coli].	31.54	612	378	17	1	581	1	602	3e-82	285
rs:WP_005817457	DNA topoisomerase III [Bacteroides fragilis].	30.81	727	387	25	1	629	1	709	3e-82	286
rs:WP_036117504	DNA topoisomerase III [Lysinibacillus sphaericus].	34.68	669	359	29	3	627	5	639	3e-82	287
rs:WP_018451999	DNA topoisomerase III [Bacteroides massiliensis].	30.21	725	392	22	1	630	1	706	3e-82	286
rs:WP_004605342	DNA topoisomerase III [[Clostridium] scindens].	31.49	670	388	20	3	627	4	647	3e-82	287
rs:WP_045631099	DNA topoisomerase III [Enterobacter cloacae].	30.81	607	389	12	1	585	1	598	3e-82	284
rs:WP_017411783	DNA topoisomerase III [Aeromonas salmonicida].	29.82	654	409	14	1	622	1	636	3e-82	285
rs:WP_038391157	DNA topoisomerase III [Salmonella bongori].	31.48	613	377	19	1	581	1	602	3e-82	285
rs:WP_025202529	DNA topoisomerase III [Aeromonas hydrophila].	30.21	652	412	16	1	624	1	637	3e-82	285
rs:WP_000765276	DNA topoisomerase III [Salmonella enterica].	29.60	679	425	18	1	646	1	659	3e-82	285
rs:WP_042362257	DNA topoisomerase III [Staphylococcus xylosus].	33.60	634	372	16	3	615	4	609	3e-82	286
rs:WP_021523123	DNA topoisomerase III [Escherichia coli].	31.86	612	376	18	1	581	1	602	3e-82	285
rs:WP_042024539	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	3e-82	285
rs:WP_024910835	DNA topoisomerase III [Serratia fonticola].	31.64	610	380	16	1	581	1	602	3e-82	285
rs:WP_027662357	DNA topoisomerase III [Escherichia coli].	31.54	612	378	17	1	581	1	602	3e-82	285
rs:WP_000779862	DNA topoisomerase III [Streptococcus pneumoniae].	33.33	597	366	15	1	590	1	572	3e-82	283
rs:WP_034440668	DNA topoisomerase [Clostridiales bacterium S5-A11].	33.39	602	352	14	1	587	1	568	3e-82	283
rs:WP_001235884	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	3e-82	285
rs:WP_009112895	DNA topoisomerase III [Brenneria sp. EniD312].	31.72	621	365	20	1	581	1	602	3e-82	285
rs:WP_042050123	DNA topoisomerase III [Aeromonas dhakensis].	30.18	656	415	16	1	621	1	648	3e-82	285
rs:WP_010857857	DNA topoisomerase III [Lysinibacillus sphaericus].	32.87	654	390	21	3	627	5	638	3e-82	287
rs:WP_032563947	DNA topoisomerase I [Bacteroides fragilis].	30.94	711	433	23	1	684	1	680	3e-82	286
rs:WP_028724189	DNA topoisomerase III [Pantoea ananatis].	29.52	664	416	15	1	629	1	647	3e-82	285
rs:WP_022210148	DNA topoisomerase III [Bacteroides cellulosilyticus CAG:158].	30.14	637	392	12	1	593	1	628	3e-82	287
rs:WP_008688344	DNA topoisomerase III [Eubacterium sp. 3_1_31].	31.65	632	386	17	3	611	4	612	3e-82	286
rs:WP_039344884	DNA topoisomerase III [Pectobacterium carotovorum].	31.29	620	369	19	1	581	1	602	4e-82	285
rs:WP_015061639	DNA topoisomerase [Ralstonia pickettii].	30.58	654	402	16	1	614	1	642	4e-82	286
tr:F8K7Y7_STRPY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.50	597	365	15	1	590	5	576	4e-82	283
rs:WP_025231015	DNA topoisomerase III [Clostridium sp. ASBs410].	31.22	663	391	19	3	627	4	639	4e-82	287
rs:WP_037364060	DNA topoisomerase, partial [Selenomonas ruminantium].	29.02	672	430	13	1	640	1	657	4e-82	285
rs:WP_001235838	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	4e-82	285
rs:WP_006070054	DNA topoisomerase III [Vibrio shilonii].	31.74	627	359	17	2	581	3	607	4e-82	285
rs:WP_035314731	DNA topoisomerase III [Brochothrix campestris].	32.10	651	395	16	3	631	4	629	4e-82	286
rs:WP_025653856	DNA topoisomerase III [Clostridiales bacterium VE202-21].	30.14	710	438	20	2	683	3	682	4e-82	286
rs:WP_001235839	DNA topoisomerase III [Escherichia coli].	31.26	643	397	19	1	608	1	633	4e-82	285
rs:WP_040976237	DNA topoisomerase [Pasteurella sp. FF6].	33.94	604	346	16	1	587	1	568	4e-82	283
rs:WP_016112910	DNA topoisomerase 3 [Bacillus cereus].	33.49	654	386	21	3	627	5	638	4e-82	286
tr:C6I107_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.93	675	402	21	1	633	1	646	4e-82	287
gp:AE014075_2103	DNA topoisomerase III [Escherichia coli CFT073]	31.81	613	375	19	1	581	20	621	4e-82	285
rs:WP_039565798	DNA topoisomerase III [Serratia marcescens].	31.60	614	375	19	1	581	1	602	4e-82	285
rs:WP_001626260	DNA topoisomerase III [Escherichia coli].	30.95	643	399	19	1	608	1	633	4e-82	285
rs:WP_002578877	DNA topoisomerase III [[Clostridium] bolteae].	29.41	697	443	18	1	671	1	674	4e-82	286
rs:WP_026707121	DNA topoisomerase I [Flavobacterium frigidarium].	32.35	711	428	22	1	684	1	685	4e-82	286
rs:WP_001235798	DNA topoisomerase III [Escherichia coli].	31.54	612	378	17	1	581	1	602	4e-82	285
rs:WP_012960832	DNA topoisomerase III [Bacillus pseudofirmus].	31.84	647	398	20	3	627	5	630	4e-82	286
rs:WP_022272640	DNA topoisomerase [Clostridium sp. CAG:58].	31.62	661	399	20	2	627	3	645	4e-82	287
rs:WP_005306353	MULTISPECIES: DNA topoisomerase III [Aeromonas].	30.18	656	415	16	1	621	1	648	4e-82	285
tr:U6RS94_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOA58661.1};	30.21	725	392	22	1	630	19	724	4e-82	286
rs:WP_013575369	MULTISPECIES: DNA topoisomerase III [Rahnella].	32.36	618	365	19	1	581	1	602	4e-82	285
rs:WP_009222474	DNA topoisomerase III [Peptoniphilus sp. oral taxon 386].	34.61	601	341	15	2	587	4	567	4e-82	283
rs:WP_044132009	DNA topoisomerase I [Bacteroides fragilis].	30.94	711	433	23	1	684	1	680	4e-82	286
rs:WP_032286490	DNA topoisomerase III [Escherichia coli].	30.75	644	399	20	1	608	1	633	4e-82	285
rs:WP_010635840	DNA topoisomerase III [Aeromonas dhakensis].	30.76	634	401	16	1	604	1	626	4e-82	285
gp:CP002211_1957	DNA topoisomerase III [Escherichia coli str. 'clone D i2']	31.81	613	375	19	1	581	20	621	4e-82	285
rs:WP_002594792	DNA topoisomerase III [[Clostridium] clostridioforme].	29.93	715	443	21	3	687	5	691	4e-82	286
rs:WP_022645779	DNA topoisomerase III [Escherichia coli].	31.54	612	378	17	1	581	1	602	4e-82	285
rs:WP_024224548	DNA topoisomerase III [Escherichia coli].	30.95	643	399	19	1	608	1	633	4e-82	285
rs:WP_001674355	DNA topoisomerase III [Escherichia coli].	30.95	643	399	19	1	608	1	633	4e-82	285
rs:WP_003031506	MULTISPECIES: DNA topoisomerase III [Streptococcus anginosus group].	34.69	588	341	15	1	576	1	557	4e-82	282
rs:WP_007895001	DNA topoisomerase III [Streptococcus pseudoporcinus].	33.33	597	366	15	1	590	1	572	4e-82	283
rs:WP_023467640	DNA topoisomerase III [Exiguobacterium sp. MH3].	30.15	723	437	26	1	681	1	697	4e-82	286
rs:WP_027899045	DNA topoisomerase III [Pseudomonas syringae].	29.61	662	416	17	1	629	1	645	4e-82	285
rs:WP_000779864	DNA topoisomerase III [Streptococcus agalactiae].	33.17	597	367	15	1	590	1	572	4e-82	283
rs:WP_008782576	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	30.52	711	437	22	1	684	1	681	4e-82	286
rs:WP_004310027	MULTISPECIES: DNA topoisomerase I [Bacteroides].	29.90	709	439	20	1	678	1	682	4e-82	286
rs:WP_046472782	DNA topoisomerase III [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	4e-82	286
rs:WP_035398234	DNA topoisomerase III [Exiguobacterium sp. OS-77].	30.15	723	437	26	1	681	1	697	4e-82	286
tr:G7EED8_9GAMM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.92	614	372	12	1	579	8	610	4e-82	285
rs:WP_034122848	DNA topoisomerase III, partial [Peptococcaceae bacterium BICA1-7].	30.99	697	428	21	3	673	4	673	4e-82	285
rs:WP_042988115	DNA topoisomerase I [Bacteroides fragilis].	30.94	711	433	23	1	684	1	680	4e-82	286
rs:WP_041992690	hypothetical protein [Capnocytophaga cynodegmi].	30.44	703	432	20	1	673	1	676	4e-82	286
rs:WP_001480500	DNA topoisomerase III [Escherichia coli].	30.75	644	399	20	1	608	1	633	4e-82	285
rs:WP_001235828	DNA topoisomerase III [Escherichia sp. TW09231].	32.14	613	373	19	1	581	1	602	4e-82	285
rs:WP_004225545	DNA topoisomerase III [Lysinibacillus fusiformis].	34.08	666	367	26	3	627	5	639	4e-82	286
rs:WP_023625750	DNA topoisomerase III [Bacillus sp. 17376].	31.01	661	400	17	3	646	4	625	4e-82	286
tr:W2CXK5_9PORP	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.92	605	386	14	1	583	1	589	4e-82	283
rs:WP_014708275	DNA topoisomerase [Methylophaga frappieri].	31.01	674	409	19	1	629	1	663	5e-82	285
rs:WP_040076043	DNA topoisomerase III [Enterobacteriaceae bacterium ATCC 29904].	31.65	654	396	21	1	622	1	635	5e-82	284
tr:D1W4E5_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.94	711	433	23	1	684	20	699	5e-82	286
rs:WP_023059450	DNA topoisomerase III [Peptoniphilus sp. BV3AC2].	33.00	597	368	15	1	590	1	572	5e-82	282
rs:WP_018873968	MULTISPECIES: hypothetical protein [Thioalkalivibrio].	28.53	701	423	17	41	670	1	694	5e-82	286
rs:WP_014699893	MULTISPECIES: DNA topoisomerase III [Pectobacterium].	31.99	619	366	21	1	581	1	602	5e-82	284
rs:WP_001235846	DNA topoisomerase III [Escherichia coli].	30.95	643	399	19	1	608	1	633	5e-82	285
tr:A0A0C7I149_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.13	667	354	25	3	631	5	617	5e-82	286
rs:WP_001235883	DNA topoisomerase III [Salmonella bongori].	31.48	613	377	19	1	581	1	602	5e-82	284
rs:WP_028357446	DNA topoisomerase III [Brackiella oedipodis].	31.94	739	399	30	3	673	5	707	5e-82	290
rs:WP_038704788	DNA topoisomerase III [Planococcus sp. PAMC 21323].	34.09	657	370	24	3	627	4	629	5e-82	286
rs:WP_002672191	DNA topoisomerase [Capnocytophaga ochracea].	31.33	715	421	25	1	675	1	685	5e-82	286
rs:WP_047200380	DNA topoisomerase [Streptococcus agalactiae].	33.39	602	352	14	1	587	1	568	5e-82	282
rs:WP_040956109	DNA topoisomerase III [Virgibacillus sp. SK37].	32.11	629	395	15	3	615	5	617	5e-82	286
rs:WP_020844018	DNA topoisomerase III [Salmonella bongori].	31.48	613	377	19	1	581	1	602	5e-82	284
rs:WP_044920444	hypothetical protein [Anaerostipes hadrus].	30.55	707	440	18	1	673	1	690	5e-82	286
rs:WP_011066983	DNA topoisomerase III [Oceanobacillus iheyensis].	32.49	671	387	20	3	638	5	644	5e-82	286
rs:WP_024026550	DNA topoisomerase III [Bacillus vireti].	33.33	654	387	20	3	627	5	638	5e-82	286
rs:WP_028293801	DNA topoisomerase III [Oceanobacter kriegii].	31.33	616	376	15	1	576	1	609	5e-82	285
rs:WP_001718384	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	5e-82	285
rs:WP_009249709	DNA topoisomerase III [Lachnospiraceae bacterium 5_1_57FAA].	31.63	664	395	20	3	627	4	647	5e-82	286
tr:Q6D9T7_PECAS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.34	651	399	15	1	614	2	628	5e-82	285
tr:A0A0C7GEP2_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.68	667	357	24	3	631	5	617	5e-82	286
rs:WP_034494731	DNA topoisomerase III [Buttiauxella agrestis].	32.35	612	373	18	1	581	1	602	5e-82	285
rs:WP_023004936	DNA topoisomerase III [Halomonas sp. PBN3].	30.38	609	385	14	1	581	1	598	5e-82	284
rs:WP_009123155	DNA topoisomerase III [Bacteroides clarus].	29.90	729	385	20	1	625	1	707	5e-82	286
rs:WP_005805519	DNA topoisomerase I [Bacteroides fragilis].	31.38	701	416	21	1	676	1	661	5e-82	285
tr:A0A0C7JF70_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.68	667	357	24	3	631	5	617	5e-82	286
rs:WP_026739409	DNA topoisomerase III [Lonsdalea quercina].	30.78	614	375	18	1	578	1	600	5e-82	284
rs:WP_032569313	DNA topoisomerase I [Bacteroides fragilis].	30.66	711	436	22	1	684	1	681	6e-82	285
rs:WP_019376018	DNA topoisomerase III [Virgibacillus halodenitrificans].	32.01	628	397	15	3	615	5	617	6e-82	286
rs:WP_038265548	DNA topoisomerase III [Xenorhabdus cabanillasii].	30.14	637	408	13	1	614	1	623	6e-82	285
rs:WP_009221177	DNA topoisomerase III [Lachnospiraceae oral taxon 107].	34.47	589	335	15	1	571	1	556	6e-82	282
rs:WP_007660662	DNA topoisomerase I [Bacteroides intestinalis].	30.94	711	433	23	1	684	1	680	6e-82	286
rs:WP_021806609	DNA topoisomerase III [Serratia fonticola].	31.64	610	380	16	1	581	1	602	6e-82	284
rs:WP_040095505	DNA topoisomerase III [Aeromonas australiensis].	30.06	652	414	14	1	624	1	638	6e-82	285
rs:WP_040133203	DNA topoisomerase III [Providencia stuartii].	32.46	650	379	22	1	609	1	631	6e-82	284
rs:WP_045146800	DNA topoisomerase III [Escherichia coli].	31.86	612	376	18	1	581	1	602	6e-82	284
rs:WP_024209312	DNA topoisomerase III [Escherichia coli].	30.85	645	397	21	1	608	1	633	6e-82	284
rs:WP_027635678	DNA topoisomerase III [Clostridium butyricum].	32.59	632	385	16	3	615	5	614	6e-82	286
tr:C3GTB4_BACTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.32	729	430	22	3	680	10	711	6e-82	286
rs:WP_039220949	DNA topoisomerase III [Clostridium novyi].	32.58	663	380	21	3	627	5	638	6e-82	286
rs:WP_025906799	DNA topoisomerase III [Staphylococcus sciuri].	31.63	626	395	12	3	615	4	609	6e-82	286
rs:WP_039290396	DNA topoisomerase III [Pectobacterium atrosepticum].	29.34	651	399	15	1	614	1	627	6e-82	285
rs:WP_029053986	DNA topoisomerase III [Sporosarcina ureae].	33.03	660	382	21	3	627	5	639	6e-82	286
rs:WP_032557320	DNA topoisomerase III [Bacteroides fragilis].	30.81	727	387	25	1	629	1	709	6e-82	286
rs:WP_020827202	DNA topoisomerase III [Serratia liquefaciens].	31.91	611	377	18	1	581	1	602	6e-82	284
rs:WP_047094745	DNA topoisomerase I [Chryseobacterium indologenes].	32.43	700	420	23	1	673	1	674	6e-82	285
rs:WP_032353289	DNA topoisomerase III, partial [Escherichia coli].	31.86	612	376	18	1	581	1	602	6e-82	283
rs:WP_039430831	DNA topoisomerase I [Porphyromonas gulae].	29.66	698	455	16	1	678	1	682	6e-82	285
rs:WP_026712906	DNA topoisomerase I [Flavobacterium daejeonense].	32.29	700	421	22	1	673	1	674	6e-82	285
rs:WP_031904145	DNA topoisomerase III [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	6e-82	286
rs:WP_032225326	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	6e-82	284
tr:F4SKI5_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.90	644	398	20	1	608	10	642	6e-82	285
rs:WP_032944498	DNA topoisomerase I [Bacteroides vulgatus].	30.94	711	433	23	1	684	1	680	6e-82	285
rs:WP_001235841	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	6e-82	284
tr:A0A077VCU2_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.75	629	383	13	3	615	4	608	6e-82	286
rs:WP_031795285	DNA topoisomerase III [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	6e-82	286
rs:WP_032724076	DNA topoisomerase III [Enterobacter aerogenes].	31.03	609	389	12	1	587	1	600	6e-82	283
rs:WP_027089858	DNA topoisomerase III [[Clostridium] saccharogumia].	31.50	692	430	18	1	671	1	669	6e-82	285
rs:WP_002440314	DNA topoisomerase III [Shimwellia blattae].	31.26	643	385	22	1	604	1	625	6e-82	284
rs:WP_001235775	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	6e-82	284
rs:WP_011969196	DNA topoisomerase III [Clostridium beijerinckii].	33.28	655	383	21	3	627	5	635	6e-82	286
rs:WP_038349224	DNA topoisomerase III [Escherichia coli].	30.64	643	401	18	1	608	1	633	6e-82	284
rs:WP_000114567	DNA topoisomerase III [Bacillus thuringiensis].	30.32	729	430	22	3	680	4	705	6e-82	286
rs:WP_022375467	DNA topoisomerase [Firmicutes bacterium CAG:270].	32.22	627	373	18	2	612	3	593	6e-82	285
rs:WP_004310571	DNA topoisomerase I [Bacteroides ovatus].	30.89	709	436	21	1	684	1	680	6e-82	285
rs:WP_044865123	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	6e-82	284
rs:WP_016596683	DNA topoisomerase III, partial [Yersinia pestis].	31.88	596	355	20	1	560	1	581	6e-82	283
rs:WP_044666441	DNA topoisomerase [Streptococcus suis].	34.78	598	341	16	3	583	5	570	6e-82	282
rs:WP_023975063	DNA topoisomerase III [Clostridium pasteurianum].	33.28	655	383	21	3	627	5	635	7e-82	286
rs:WP_007566776	DNA topoisomerase III [Bacteroides coprocola].	32.07	605	376	14	1	588	1	587	7e-82	285
rs:WP_001235782	DNA topoisomerase III [Escherichia sp. TW14182].	32.03	612	375	18	1	581	1	602	7e-82	284
rs:WP_022233498	DNA topoisomerase III [Bacteroides sp. CAG:443].	31.62	604	380	12	1	588	1	587	7e-82	285
rs:WP_036182463	DNA topoisomerase III [Lysinibacillus manganicus].	32.68	664	379	23	3	627	5	639	7e-82	286
rs:WP_012101445	DNA topoisomerase III [Clostridium kluyveri].	32.77	653	389	18	3	627	5	635	7e-82	286
rs:WP_029341148	DNA topoisomerase III [Exiguobacterium acetylicum].	29.85	717	447	23	1	681	1	697	7e-82	285
rs:WP_024910502	DNA topoisomerase III [Serratia fonticola].	30.09	638	404	15	1	611	1	623	7e-82	285
rs:WP_025121009	MULTISPECIES: DNA topoisomerase III [Serratia].	31.80	610	379	16	1	581	1	602	7e-82	284
rs:WP_036940411	DNA topoisomerase III [Providencia stuartii].	32.31	650	380	22	1	609	1	631	7e-82	284
rs:WP_007594042	DNA topoisomerase III [Lachnoanaerobaculum sp. OBRC5-5].	33.72	605	342	16	1	585	1	566	7e-82	282
rs:WP_039086821	DNA topoisomerase III [Gallibacterium anatis].	31.26	627	370	16	1	581	1	612	7e-82	284
rs:WP_003699926	DNA topoisomerase III [Neisseria gonorrhoeae].	31.71	659	387	20	1	610	1	645	7e-82	285
tr:Q7VLX0_HAEDU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.91	633	380	20	1	600	2	616	7e-82	284
rs:WP_045754349	DNA topoisomerase I [Sphingobacterium sp. PM2-P1-29].	32.24	701	420	24	1	673	1	674	7e-82	285
rs:WP_032559101	MULTISPECIES: DNA topoisomerase I [Bacteroides].	30.94	711	433	23	1	684	1	680	7e-82	285
tr:A0A0C7S3W2_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.68	667	357	24	3	631	5	617	7e-82	285
rs:WP_022126066	DNA topoisomerase III [Bacteroides coprocola CAG:162].	32.07	605	376	14	1	588	1	587	7e-82	285
rs:WP_032102106	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	7e-82	284
gpu:CP009928_787	DNA topoisomerase I [Chryseobacterium gallinarum]	31.53	701	434	19	1	677	1	679	7e-82	285
rs:WP_008915794	DNA topoisomerase III [Providencia sneebia].	33.07	626	363	20	1	586	1	610	7e-82	284
rs:WP_016085280	DNA topoisomerase III [Bacillus cereus].	30.33	732	434	23	3	680	4	713	7e-82	286
rs:WP_044710862	DNA topoisomerase III [Escherichia coli].	31.15	610	383	16	1	581	1	602	7e-82	284
rs:WP_016599634	DNA topoisomerase III, partial [Yersinia pestis].	31.88	596	355	20	1	560	1	581	7e-82	282
rs:WP_026161838	DNA topoisomerase I [Porphyromonas somerae].	31.65	695	423	22	4	673	5	672	7e-82	285
rs:WP_042644457	DNA topoisomerase III [Aeromonas eucrenophila].	30.59	631	395	13	1	599	1	620	7e-82	284
rs:WP_021573593	DNA topoisomerase III [Escherichia coli].	32.03	612	375	18	1	581	1	602	7e-82	284
rs:WP_009346275	DNA topoisomerase III [Peptoniphilus sp. oral taxon 836].	33.44	601	353	13	1	587	1	568	7e-82	282
rs:WP_013815808	DNA topoisomerase I [Porphyromonas gingivalis].	30.03	726	437	23	1	684	1	697	7e-82	285
rs:WP_025434822	DNA topoisomerase [Eubacterium acidaminophilum].	34.06	596	359	15	1	587	1	571	7e-82	282
rs:WP_013308786	DNA topoisomerase III [Paenibacillus polymyxa].	31.39	634	376	19	3	611	4	603	7e-82	285
rs:WP_029569410	DNA topoisomerase III [Pantoea ananatis].	29.22	664	418	14	1	629	1	647	7e-82	285
rs:WP_013485776	DNA topoisomerase III [Ethanoligenens harbinense].	28.95	715	441	18	1	681	1	682	7e-82	285
rs:WP_005812009	DNA topoisomerase I [Bacteroides fragilis].	30.94	711	433	23	1	684	1	680	7e-82	285
rs:WP_038611241	DNA topoisomerase I [Bacteroides dorei].	29.66	698	450	19	1	677	1	678	7e-82	285
rs:WP_029435132	DNA topoisomerase III [Bilophila wadsworthia].	30.26	661	412	17	1	631	1	642	8e-82	287
rs:WP_015701195	DNA topoisomerase III [Pantoea ananatis].	29.84	667	410	17	1	629	1	647	8e-82	285
rs:WP_016221561	DNA topoisomerase III [Dorea sp. 5-2].	32.78	665	383	23	3	627	4	644	8e-82	286
rs:WP_005833152	MULTISPECIES: DNA topoisomerase III [Bacteroides].	30.71	648	395	13	1	603	1	639	8e-82	286
rs:WP_036293444	DNA topoisomerase [Methylobacter whittenburyi].	31.29	620	375	14	1	580	1	609	8e-82	285
rs:WP_003877739	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	8e-82	284
rs:WP_003655601	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	8e-82	284
rs:WP_000838495	DNA topoisomerase III [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	8e-82	285
rs:WP_042016249	DNA topoisomerase III [Aeromonas caviae].	30.94	627	397	14	1	599	1	619	8e-82	284
rs:WP_009235005	DNA topoisomerase III [Prevotella sp. oral taxon 472].	30.52	688	408	18	1	630	1	676	8e-82	285
rs:WP_004920303	DNA topoisomerase III [Providencia stuartii].	32.85	627	363	21	1	586	1	610	8e-82	284
rs:WP_009382803	DNA topoisomerase III [Staphylococcus massiliensis].	32.06	652	393	16	3	631	4	628	8e-82	285
rs:WP_008564100	DNA topoisomerase I [Prevotella maculosa].	31.43	719	436	25	1	684	1	697	8e-82	285
rs:WP_019677543	DNA topoisomerase III [Rheinheimera perlucida].	31.24	621	381	13	1	581	1	615	8e-82	285
rs:WP_017722920	DNA topoisomerase III [Staphylococcus xylosus].	34.02	632	372	19	3	615	4	609	8e-82	285
rs:WP_025719810	DNA topoisomerase III [Paenibacillus polymyxa].	31.39	634	376	19	3	611	4	603	8e-82	285
rs:WP_020405854	DNA topoisomerase [Hahella ganghwensis].	32.15	622	373	18	1	584	1	611	8e-82	285
rs:WP_032259514	DNA topoisomerase III [Escherichia coli].	30.95	643	399	19	1	608	1	633	8e-82	284
rs:WP_032114974	DNA topoisomerase III [Arsenophonus endosymbiont of Nilaparvata lugens].	32.40	608	376	15	2	581	3	603	8e-82	284
tr:A0A077PMV3_XENBV	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.95	641	406	13	1	614	5	629	8e-82	284
rs:WP_006705692	DNA topoisomerase III [Candidatus Regiella insecticola].	31.54	612	378	16	1	581	1	602	8e-82	283
rs:WP_001520656	DNA topoisomerase III [Escherichia coli].	31.86	612	376	18	1	581	1	602	8e-82	284
rs:WP_007045892	DNA topoisomerase III [Subdoligranulum variabile].	29.08	698	445	18	1	671	1	675	8e-82	285
tr:B9E0J7_CLOK1	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.77	653	389	18	3	627	7	637	8e-82	286
rs:WP_001687610	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	8e-82	284
rs:WP_001497630	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	8e-82	284
sp:TOP3_STAAB	RecName: Full=Putative DNA topoisomerase 3; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	33.02	636	372	18	3	615	4	608	8e-82	285
rs:WP_033552723	DNA topoisomerase III [Escherichia coli].	31.86	612	376	18	1	581	1	602	8e-82	284
rs:WP_020244836	DNA topoisomerase III [Escherichia coli].	31.86	612	376	18	1	581	1	602	8e-82	284
rs:WP_021556882	DNA topoisomerase III [Escherichia coli].	30.95	643	399	19	1	608	1	633	8e-82	284
rs:WP_031911917	DNA topoisomerase III [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	8e-82	285
rs:WP_014994483	MULTISPECIES: DNA topoisomerase III [Alcanivorax].	30.04	709	439	20	3	670	4	696	8e-82	285
rs:WP_001552958	DNA topoisomerase III [Escherichia coli].	31.86	612	376	18	1	581	1	602	8e-82	284
rs:WP_025675355	DNA topoisomerase III [Paenibacillus polymyxa].	31.19	638	372	21	3	611	4	603	8e-82	285
rs:WP_038194406	DNA topoisomerase III [Xenorhabdus bovienii].	29.95	641	406	13	1	614	1	625	8e-82	284
rs:WP_000838508	DNA topoisomerase III [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	9e-82	285
rs:WP_000838494	DNA topoisomerase III [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	9e-82	285
rs:WP_038673289	DNA topoisomerase III [Pelosinus sp. UFO1].	32.78	668	398	23	3	638	5	653	9e-82	286
tr:B8DNH0_DESVM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.91	688	420	14	3	626	5	680	9e-82	288
rs:WP_037567095	DNA topoisomerase III [Staphylococcus agnetis].	32.64	628	385	17	3	615	4	608	9e-82	285
tr:A0A078R730_BACVU	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:KDS29757.1};	30.74	706	437	20	1	678	3	684	9e-82	285
rs:WP_028504491	hypothetical protein [Ruminococcus albus].	30.10	701	440	18	1	678	1	674	9e-82	285
rs:WP_032602824	DNA topoisomerase I, partial [Bacteroides fragilis].	30.73	703	430	22	1	676	1	673	9e-82	284
rs:WP_031911617	DNA topoisomerase III [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	9e-82	285
rs:WP_020278829	DNA topoisomerase III [Geobacillus kaustophilus].	28.71	721	463	19	1	681	1	710	9e-82	285
rs:WP_041603685	DNA topoisomerase III [Haemophilus ducreyi].	31.91	633	380	20	1	600	1	615	9e-82	283
rs:WP_000838473	DNA topoisomerase III [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	9e-82	285
rs:WP_045832167	DNA topoisomerase III [Pantoea sp. BL1].	32.08	611	362	18	1	574	1	595	9e-82	283
rs:WP_021633201	DNA topoisomerase [Clostridium sp. ATCC BAA-442].	29.42	707	438	23	1	682	1	671	9e-82	285
rs:WP_012988057	DNA topoisomerase III [Xenorhabdus bovienii].	30.27	641	402	14	1	614	1	623	9e-82	284
rs:WP_001235843	DNA topoisomerase III [Shigella dysenteriae].	31.10	643	398	19	1	608	1	633	9e-82	284
rs:WP_000779857	DNA topoisomerase III [Streptococcus agalactiae].	32.95	601	356	13	1	587	1	568	9e-82	281
rs:WP_043170626	MULTISPECIES: DNA topoisomerase III [Aeromonas].	29.88	656	417	14	1	621	1	648	9e-82	284
rs:WP_004291456	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	30.94	711	433	23	1	684	1	680	9e-82	285
rs:WP_040886141	DNA topoisomerase III [Marinobacterium stanieri].	31.10	611	382	15	1	581	1	602	9e-82	284
rs:WP_015374805	DNA topoisomerase III [Geobacillus sp. GHH01].	30.50	659	405	17	3	646	4	624	1e-81	285
rs:WP_039020743	DNA topoisomerase III [Escherichia coli].	31.86	612	376	18	1	581	1	602	1e-81	283
rs:WP_021552583	DNA topoisomerase III [Escherichia coli].	31.86	612	376	18	1	581	1	602	1e-81	283
rs:WP_036757769	DNA topoisomerase [Peptoniphilus lacrimalis].	33.50	597	365	14	1	590	1	572	1e-81	281
rs:WP_033017260	DNA topoisomerase III [Pseudoalteromonas sp. BSi20652].	31.92	614	372	12	1	579	1	603	1e-81	283
rs:WP_001578461	DNA topoisomerase III [Escherichia coli].	31.20	609	384	15	1	581	1	602	1e-81	284
rs:WP_038605799	DNA topoisomerase I [Bacteroides dorei].	28.84	697	457	15	1	677	1	678	1e-81	285
rs:WP_007889711	DNA topoisomerase III [Pantoea sp. GM01].	32.08	611	362	18	1	574	1	595	1e-81	283
rs:WP_001235826	DNA topoisomerase III [Escherichia coli].	31.86	612	376	18	1	581	1	602	1e-81	283
rs:WP_020454016	DNA topoisomerase III [Enterobacter sp. R4-368].	31.54	612	378	18	1	581	1	602	1e-81	283
tr:A0A0C7PZI4_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.68	667	357	24	3	631	5	617	1e-81	285
rs:WP_016158144	MULTISPECIES: DNA topoisomerase III [Escherichia].	31.65	613	376	19	1	581	1	602	1e-81	283
rs:WP_039069501	DNA topoisomerase III [Staphylococcus xylosus].	33.23	626	385	15	3	615	4	609	1e-81	285
rs:WP_031592645	DNA topoisomerase III [Pantoea agglomerans].	29.69	687	422	17	1	645	1	668	1e-81	284
rs:WP_007895910	DNA topoisomerase III [Streptococcus pseudoporcinus].	33.67	588	358	15	1	581	1	563	1e-81	281
rs:WP_037589019	DNA topoisomerase III [Staphylococcus aureus].	31.47	626	396	12	3	615	4	609	1e-81	285
rs:WP_024173215	DNA topoisomerase III [Escherichia coli].	30.95	643	399	19	1	608	1	633	1e-81	284
tr:A0A0C7EU68_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.68	667	357	24	3	631	5	617	1e-81	285
rs:WP_035070810	DNA topoisomerase III, partial [Desulfovibrio termitidis].	28.01	689	419	14	3	626	5	681	1e-81	288
rs:WP_004063538	DNA topoisomerase III [Eubacterium plexicaudatum].	30.00	700	437	20	3	673	5	680	1e-81	285
tr:A0A078RJZ0_BACVU	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:KDS34242.1};	30.74	706	437	20	1	678	3	684	1e-81	285
rs:WP_016680565	DNA topoisomerase III, partial [Yersinia pestis].	31.88	596	355	20	1	560	1	581	1e-81	282
rs:WP_046044421	topoisomerase [Staphylococcus epidermidis].	34.44	633	367	22	3	615	4	608	1e-81	285
rs:WP_011264006	DNA topoisomerase III [Aliivibrio fischeri].	31.09	669	412	18	1	640	1	649	1e-81	284
rs:WP_007764104	DNA topoisomerase I [Bacteroides finegoldii].	31.01	703	427	23	1	676	1	672	1e-81	284
rs:WP_002486256	DNA topoisomerase III [Staphylococcus epidermidis].	33.97	633	370	20	3	615	4	608	1e-81	285
rs:WP_004611958	DNA topoisomerase III [Tyzzerella nexilis].	30.77	650	397	18	1	627	1	620	1e-81	285
rs:WP_002841135	DNA topoisomerase III [Finegoldia magna].	33.17	597	367	14	1	590	1	572	1e-81	281
rs:WP_004614870	DNA topoisomerase III [Tyzzerella nexilis].	31.61	658	394	18	3	627	4	638	1e-81	285
rs:WP_031797387	DNA topoisomerase III [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	1e-81	285
rs:WP_044960767	DNA topoisomerase III [Faecalibacterium prausnitzii].	30.07	695	437	18	2	670	5	676	1e-81	285
rs:WP_008772022	DNA topoisomerase I [Bacteroides sp. 2_1_33B].	29.51	698	451	19	1	677	1	678	1e-81	285
rs:WP_026574293	DNA topoisomerase III [Bacillus sp. UNC438CL73TsuS30].	32.93	665	375	24	3	627	5	638	1e-81	285
rs:WP_033865488	DNA topoisomerase III [Escherichia coli].	30.22	642	405	18	1	608	1	633	1e-81	283
rs:WP_025783241	DNA topoisomerase III [Sporosarcina sp. D27].	33.03	651	388	19	3	627	5	633	1e-81	285
rs:WP_034828805	DNA topoisomerase III [Enterobacter cancerogenus].	32.08	611	362	18	1	574	1	595	1e-81	283
rs:WP_000779858	DNA topoisomerase III [Streptococcus agalactiae].	33.44	601	353	13	1	587	1	568	1e-81	281
rs:WP_045816089	DNA topoisomerase III [Pantoea sp. SM3].	32.08	611	362	18	1	574	1	595	1e-81	283
rs:WP_033118340	DNA topoisomerase III [Intestinimonas butyriciproducens].	29.45	652	414	18	3	627	5	637	1e-81	285
rs:WP_024221941	DNA topoisomerase III [Escherichia coli].	30.95	643	399	19	1	608	1	633	1e-81	283
rs:WP_000779866	DNA topoisomerase III [Streptococcus agalactiae].	33.17	597	367	14	1	590	1	572	1e-81	281
rs:WP_031913504	DNA topoisomerase III [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	1e-81	285
rs:WP_012774824	DNA topoisomerase III [Photobacterium damselae].	30.58	618	387	14	1	583	1	611	1e-81	284
rs:WP_042072495	DNA topoisomerase III [Aeromonas enteropelogenes].	29.73	656	411	14	1	624	1	638	1e-81	283
rs:WP_032561755	DNA topoisomerase III [Bacteroides fragilis].	30.67	727	388	25	1	629	1	709	1e-81	285
rs:WP_044191484	DNA topoisomerase III [Escherichia coli].	30.95	643	399	19	1	608	1	633	1e-81	283
rs:WP_043142638	DNA topoisomerase III [Aeromonas salmonicida].	30.06	662	397	19	1	622	1	636	1e-81	283
rs:WP_000838486	DNA topoisomerase 3 [Staphylococcus aureus].	33.18	636	371	18	3	615	4	608	1e-81	285
rs:WP_033843881	DNA topoisomerase III [Geobacillus subterraneus].	30.55	658	406	17	3	646	4	624	1e-81	285
rs:WP_038256049	DNA topoisomerase III [Xenorhabdus bovienii].	29.95	641	406	13	1	614	1	625	1e-81	284
rs:WP_016421320	DNA topoisomerase III [Capnocytophaga granulosa].	31.60	712	423	25	1	675	1	685	1e-81	285
rs:WP_021550670	DNA topoisomerase III [Escherichia coli].	31.97	613	374	19	1	581	1	602	1e-81	283
rs:WP_036930306	DNA topoisomerase III [Prevotella sp. 10(H)].	30.29	690	408	16	1	630	1	677	1e-81	285
rs:WP_039159053	DNA topoisomerase III [Gallibacterium anatis].	31.26	627	370	16	1	581	1	612	1e-81	283
rs:WP_001519770	DNA topoisomerase III [Escherichia coli].	31.86	612	376	18	1	581	1	602	1e-81	283
rs:WP_012656100	DNA topoisomerase III [Macrococcus caseolyticus].	32.31	650	391	17	3	631	4	625	1e-81	285
tr:A8SHN5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.07	695	437	18	2	670	7	678	1e-81	285
rs:WP_041964452	DNA topoisomerase III [Bacillus selenatarsenatis].	30.50	659	406	16	3	646	4	625	1e-81	285
rs:WP_030034462	DNA topoisomerase III [Clostridium botulinum].	32.05	677	392	26	3	638	5	654	1e-81	285
rs:WP_031885526	DNA topoisomerase III [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	1e-81	285
rs:WP_040287614	DNA topoisomerase III [Sporosarcina koreensis].	32.51	649	394	17	3	627	14	642	1e-81	285
rs:WP_015017147	DNA topoisomerase III [Streptococcus dysgalactiae].	33.06	602	354	14	1	587	1	568	1e-81	281
rs:WP_002989354	MULTISPECIES: DNA topoisomerase III [Streptococcus].	33.06	602	354	14	1	587	1	568	1e-81	281
rs:WP_034887878	DNA topoisomerase III [Erwinia typographi].	31.57	624	362	20	1	581	1	602	1e-81	283
rs:WP_039384680	DNA topoisomerase III [Pantoea sp. PSNIH1].	31.83	619	367	19	1	581	1	602	1e-81	283
rs:WP_017725889	hypothetical protein [Bacillus sp. L1(2012)].	31.28	649	403	19	3	627	5	634	1e-81	285
rs:WP_024599846	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	31.85	631	358	20	1	581	1	609	1e-81	283
rs:WP_027097876	DNA topoisomerase III [Clostridium paraputrificum].	32.92	653	389	19	1	627	3	632	1e-81	285
rs:WP_007587111	DNA topoisomerase III [Pseudoalteromonas sp. BSi20429].	32.08	614	371	13	1	579	1	603	1e-81	283
rs:WP_036628384	DNA topoisomerase III [Oscillospiraceae bacterium VE202-24].	29.55	714	440	21	2	683	3	685	1e-81	284
rs:WP_000114569	DNA topoisomerase III [Bacillus cereus].	29.57	727	438	20	3	680	4	705	1e-81	285
tr:A0A0A5LTA1_SERMA	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.60	614	375	19	1	581	1	602	1e-81	283
gpu:AP013045_2147	DNA topoisomerase III [Tannerella forsythia KS16]	31.29	719	437	24	1	684	1	697	1e-81	285
rs:WP_039644438	DNA topoisomerase III [Staphylococcus hyicus].	31.80	632	385	15	3	615	4	608	1e-81	285
rs:WP_036868224	DNA topoisomerase I [Porphyromonas canoris].	30.88	719	440	23	1	684	1	697	1e-81	285
rs:WP_011072959	DNA topoisomerase III [Shewanella oneidensis].	31.96	629	373	14	1	581	1	622	1e-81	285
rs:WP_032569621	DNA topoisomerase I [Bacteroides fragilis].	29.51	698	451	19	1	677	1	678	1e-81	284
rs:WP_016284646	DNA topoisomerase III [Lachnospiraceae bacterium A4].	30.00	700	434	20	1	670	1	674	1e-81	284
rs:WP_008110346	DNA topoisomerase III [Pantoea sp. YR343].	32.08	611	362	18	1	574	1	595	1e-81	283
rs:WP_001235812	DNA topoisomerase III [Escherichia coli].	30.75	644	399	20	1	608	1	633	1e-81	283
tr:A0A0C7I5H8_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.53	667	358	24	3	631	5	617	2e-81	285
rs:WP_013345169	DNA topoisomerase III [Ferrimonas balearica].	32.07	608	379	14	1	581	1	601	2e-81	283
rs:WP_044567173	DNA topoisomerase [Anaerococcus sp. 9402080].	33.17	597	367	15	1	590	1	572	2e-81	281
rs:WP_032558364	DNA topoisomerase I [Bacteroides fragilis].	29.51	698	451	19	1	677	1	678	2e-81	284
rs:WP_026777671	DNA topoisomerase III [Polaribacter sp. Hel_I_88].	29.71	717	444	18	1	676	1	698	2e-81	286
rs:WP_020001908	hypothetical protein [Desulfovibrio desulfuricans].	32.39	639	374	15	1	614	1	606	2e-81	284
rs:WP_028389296	DNA topoisomerase [Legionella fairfieldensis].	31.09	685	416	19	1	642	1	672	2e-81	284
rs:WP_040084318	DNA topoisomerase III [Escherichia coli].	30.95	643	399	19	1	608	1	633	2e-81	283
rs:WP_007636905	DNA topoisomerase III [Glaciecola psychrophila].	31.30	623	375	20	1	581	1	612	2e-81	283
rs:WP_025460229	DNA topoisomerase III [Neisseria meningitidis].	31.41	659	389	20	1	610	1	645	2e-81	284
rs:WP_038501299	DNA topoisomerase III [Basilea psittacipulmonis].	30.83	733	423	27	3	679	5	709	2e-81	287
tr:G9QKK7_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.09	645	401	18	3	626	4	632	2e-81	285
tr:A0A0C7GXA1_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.68	664	361	24	3	631	5	617	2e-81	284
rs:WP_021680133	DNA topoisomerase [Porphyromonas gingivalis].	29.24	701	458	15	1	680	1	684	2e-81	284
rs:WP_017209631	DNA topoisomerase III [Clostridium beijerinckii].	33.13	655	384	21	3	627	5	635	2e-81	285
rs:WP_033553586	DNA topoisomerase III [Escherichia coli].	31.86	612	376	18	1	581	1	602	2e-81	283
rs:WP_038646639	DNA topoisomerase III [Pantoea rwandensis].	32.08	611	362	18	1	574	1	595	2e-81	283
rs:WP_001764957	DNA topoisomerase III [Escherichia coli].	30.35	649	404	16	1	616	1	634	2e-81	284
rs:WP_045288446	DNA topoisomerase III [Pluralibacter gergoviae].	31.52	606	372	19	1	574	1	595	2e-81	283
rs:WP_040341219	DNA topoisomerase III [Bacillus smithii].	32.09	645	401	18	3	626	7	635	2e-81	285
rs:WP_031795571	DNA topoisomerase III [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	2e-81	285
rs:WP_040234617	DNA topoisomerase III [Shigella flexneri].	30.90	644	398	20	1	608	1	633	2e-81	283
rs:WP_012797160	DNA topoisomerase III [Anaerococcus prevotii].	33.17	597	367	15	1	590	1	572	2e-81	281
rs:WP_041908197	DNA topoisomerase III [Enterobacter sp. BIDMC 29].	30.86	687	413	23	1	645	1	667	2e-81	283
rs:WP_038275044	DNA topoisomerase III [Yersinia ruckeri].	30.87	609	384	15	1	581	1	600	2e-81	283
rs:WP_007845609	DNA topoisomerase I [Bacteroides dorei].	28.88	696	458	16	1	677	1	678	2e-81	284
rs:WP_018676469	DNA topoisomerase I [Riemerella columbina].	30.94	711	433	23	1	684	1	680	2e-81	284
rs:WP_015374908	DNA topoisomerase I [Geobacillus sp. GHH01].	28.85	721	462	20	1	681	1	710	2e-81	285
rs:WP_001235882	DNA topoisomerase III [Salmonella enterica].	31.58	627	371	21	1	581	1	615	2e-81	283
rs:WP_022479411	DNA topoisomerase III [Prevotella sp. CAG:891].	28.45	724	413	16	1	630	1	713	2e-81	285
rs:WP_026648908	DNA topoisomerase III [Blautia wexlerae].	31.32	696	426	20	1	671	1	669	2e-81	284
tr:A0A0A1S5R5_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.68	667	357	24	3	631	5	617	2e-81	284
rs:WP_019150869	DNA topoisomerase I [Alistipes senegalensis].	31.01	703	429	23	1	676	1	674	2e-81	284
rs:WP_000838503	DNA topoisomerase 3 [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	2e-81	284
rs:WP_004294818	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	29.51	698	451	19	1	677	1	678	2e-81	284
rs:WP_006843458	DNA topoisomerase III [Dysgonomonas mossii].	29.84	697	426	17	1	647	1	684	2e-81	284
rs:WP_004309983	DNA topoisomerase I [Bacteroides ovatus].	28.84	697	457	16	1	677	1	678	2e-81	284
rs:WP_042287548	DNA topoisomerase III [Citrobacter sedlakii].	31.20	609	384	15	1	581	1	602	2e-81	283
rs:WP_032176337	DNA topoisomerase III [Escherichia coli].	30.95	643	399	19	1	608	1	633	2e-81	283
rs:WP_033125471	DNA topoisomerase III [Eubacterium sp. ER2].	31.24	653	403	19	3	627	4	638	2e-81	285
tr:A0A090NLN2_SHIDY	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.90	644	398	20	1	608	20	652	2e-81	283
rs:WP_022250327	DNA topoisomerase [Clostridium nexile CAG:348].	31.46	658	395	18	3	627	4	638	2e-81	285
rs:WP_010815630	DNA topoisomerase III [Enterococcus faecalis].	33.22	596	368	14	1	590	1	572	2e-81	281
tr:F4TF90_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.75	644	399	20	1	608	10	642	2e-81	283
rs:WP_009264856	DNA topoisomerase III [Lachnospiraceae bacterium 5_1_63FAA].	32.22	627	373	18	2	612	3	593	2e-81	284
rs:WP_021139862	DNA topoisomerase III [Aeromonas salmonicida].	29.80	651	407	14	1	619	1	633	2e-81	283
rs:WP_031928915	DNA topoisomerase III [Staphylococcus aureus].	33.02	642	364	18	3	615	4	608	2e-81	284
tr:A0A0C7G6G8_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.53	667	358	24	3	631	5	617	2e-81	284
rs:WP_034215261	DNA topoisomerase [Lachnoanaerobaculum sp. MSX33].	34.18	588	338	15	1	571	1	556	2e-81	281
rs:WP_008296568	DNA topoisomerase 3 [Bhargavaea cecembensis].	32.36	649	395	19	3	627	5	633	2e-81	285
rs:WP_041349811	DNA topoisomerase III [Clostridium botulinum].	31.84	669	404	24	3	638	5	654	2e-81	285
rs:WP_040227552	DNA topoisomerase III, partial [Bhargavaea cecembensis].	32.92	650	391	20	3	627	5	634	2e-81	283
rs:WP_034790651	DNA topoisomerase III [Ewingella americana].	32.08	614	372	18	1	581	1	602	2e-81	283
rs:WP_029949204	DNA topoisomerase [Parvimonas micra].	33.56	599	355	14	1	587	1	568	2e-81	280
rs:WP_001508687	DNA topoisomerase III [Escherichia coli].	30.95	643	399	19	1	608	1	633	2e-81	283
rs:WP_040376372	DNA topoisomerase III [Bacillus psychrosaccharolyticus].	32.93	656	387	21	3	627	5	638	2e-81	285
rs:WP_007362128	DNA topoisomerase [Opitutaceae bacterium TAV1].	30.23	665	402	16	1	624	1	644	2e-81	286
rs:WP_032569262	DNA topoisomerase I [Bacteroides fragilis].	30.80	711	434	23	1	684	1	680	2e-81	284
rs:WP_014908052	DNA topoisomerase III [Klebsiella pneumoniae].	30.71	609	391	11	1	587	1	600	2e-81	281
rs:WP_001688676	DNA topoisomerase III [Escherichia coli].	30.95	643	399	19	1	608	1	633	2e-81	283
rs:WP_032569384	DNA topoisomerase I [Bacteroides fragilis].	30.80	711	434	23	1	684	1	680	2e-81	284
rs:WP_042036004	DNA topoisomerase III [Aeromonas popoffii].	29.61	662	399	17	1	622	1	635	2e-81	283
rs:WP_021859574	DNA topoisomerase [Dorea sp. CAG:105].	32.10	676	389	21	3	627	4	660	2e-81	285
rs:WP_033166191	DNA topoisomerase III [Clostridium sp. KNHs205].	31.96	657	387	22	3	627	4	632	2e-81	284
rs:WP_001235822	DNA topoisomerase III [Escherichia coli].	31.37	612	379	17	1	581	1	602	2e-81	283
rs:WP_010846407	DNA topoisomerase III [Xenorhabdus nematophila].	30.73	641	401	15	1	614	1	625	2e-81	283
rs:WP_027324472	DNA topoisomerase III [Bacteroides pyogenes].	31.85	653	363	20	1	588	1	636	2e-81	286
rs:WP_039143633	DNA topoisomerase III [Gallibacterium anatis].	31.10	627	371	16	1	581	1	612	2e-81	282
rs:WP_034456056	DNA topoisomerase III [Buttiauxella agrestis].	31.81	613	375	19	1	581	1	602	3e-81	283
rs:WP_012369865	DNA topoisomerase III [Exiguobacterium sibiricum].	29.78	712	454	21	1	681	1	697	3e-81	284
rs:WP_003693191	DNA topoisomerase 3 [Neisseria gonorrhoeae].	31.56	659	388	20	1	610	1	645	3e-81	283
rs:WP_001235821	DNA topoisomerase III [Escherichia coli].	31.37	612	379	17	1	581	1	602	3e-81	283
rs:WP_020933262	conjugal transfer protein TraE, DNA topoisomerase III [Cycloclasticus zancles].	30.86	674	410	19	1	629	1	663	3e-81	283
rs:WP_003801585	DNA topoisomerase III [Escherichia coli].	30.95	643	399	19	1	608	1	633	3e-81	283
rs:WP_032572212	DNA topoisomerase I [Bacteroides fragilis].	29.61	699	449	20	1	677	1	678	3e-81	283
rs:WP_042063818	DNA topoisomerase III [Aeromonas allosaccharophila].	29.39	667	405	17	1	627	1	641	3e-81	283
rs:WP_035810237	DNA topoisomerase III [Jeotgalicoccus sp. 13MG44_air].	31.84	647	393	17	3	627	5	625	3e-81	284
rs:WP_017466745	DNA topoisomerase III [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	3e-81	284
rs:WP_018933466	hypothetical protein [Gracilibacillus lacisalsi].	32.10	648	397	18	3	627	5	632	3e-81	284
rs:WP_007392113	DNA topoisomerase [Megasphaera sp. UPII 135-E].	34.55	602	341	17	3	587	5	570	3e-81	280
rs:WP_027952894	DNA topoisomerase I [Hallella seregens].	30.92	718	441	23	1	684	1	697	3e-81	284
rs:WP_032560966	DNA topoisomerase I [Bacteroides fragilis].	29.56	697	450	19	1	676	1	677	3e-81	283
rs:WP_044956898	DNA topoisomerase III [Butyrivibrio sp. LC3010].	30.07	695	437	20	1	671	2	671	3e-81	283
rs:WP_042657288	DNA topoisomerase III [Aeromonas allosaccharophila].	30.60	621	396	13	1	593	1	614	3e-81	283
rs:WP_018346753	DNA topoisomerase III [Gallibacterium anatis].	31.10	627	371	16	1	581	1	612	3e-81	282
rs:WP_013369460	DNA topoisomerase III [Paenibacillus polymyxa].	30.77	637	376	19	3	611	4	603	3e-81	284
rs:WP_017755328	DNA topoisomerase III [Bacillus sp. ZYK].	32.42	657	392	20	3	627	5	641	3e-81	285
rs:WP_031504379	DNA topoisomerase I [Chryseobacterium haifense].	32.09	698	425	22	1	673	1	674	3e-81	283
rs:WP_018711724	DNA topoisomerase I [Bacteroides barnesiae].	30.66	711	435	23	1	684	1	680	3e-81	283
rs:WP_031907119	DNA topoisomerase III [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	3e-81	284
rs:WP_014620441	DNA topoisomerase III [Shewanella baltica].	31.54	669	410	18	1	640	1	650	3e-81	284
rs:WP_010554574	DNA topoisomerase III [Pseudoalteromonas arctica].	31.92	614	372	12	1	579	1	603	3e-81	282
rs:WP_046479673	DNA topoisomerase III [Citrobacter amalonaticus].	30.98	610	384	16	1	581	1	602	3e-81	282
rs:WP_000838502	DNA topoisomerase 3 [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	3e-81	284
rs:WP_016708066	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	32.12	604	370	13	1	574	1	594	3e-81	282
rs:WP_046337393	DNA topoisomerase III [Xenorhabdus bovienii].	30.60	670	405	19	1	633	1	647	3e-81	283
rs:WP_047198600	DNA topoisomerase [Streptococcus agalactiae].	33.28	601	354	13	1	587	1	568	3e-81	280
rs:WP_003695219	DNA topoisomerase III [Neisseria gonorrhoeae].	31.56	659	388	20	1	610	1	645	3e-81	283
rs:WP_032203321	DNA topoisomerase III [Escherichia coli].	30.95	643	399	19	1	608	1	633	3e-81	282
rs:WP_001637972	DNA topoisomerase III [Escherichia coli].	30.95	643	399	19	1	608	1	633	3e-81	282
sp:TOP3_STAAR	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	32.86	636	373	18	3	615	4	608	3e-81	284
rs:WP_006119409	DNA topoisomerase III [Pantoea stewartii].	30.83	626	364	18	1	581	1	602	3e-81	282
rs:WP_002978408	MULTISPECIES: DNA topoisomerase [Chryseobacterium].	32.15	706	414	24	1	673	1	674	3e-81	283
rs:WP_008176132	DNA topoisomerase III [Bacillus sp. B14905].	33.79	663	373	26	3	627	5	639	3e-81	284
rs:WP_035916419	DNA topoisomerase [Fusobacterium necrophorum].	33.78	601	349	15	3	588	4	570	3e-81	280
rs:WP_042994626	DNA topoisomerase I [Bacteroides fragilis].	29.90	709	439	20	1	678	1	682	3e-81	283
rs:WP_001235781	DNA topoisomerase III [Escherichia coli].	31.10	643	398	19	1	608	1	633	3e-81	282
rs:WP_026296468	DNA topoisomerase III, partial [Thioalkalivibrio sp. ALJ2].	28.39	701	424	17	41	670	3	696	3e-81	284
rs:WP_028593686	DNA topoisomerase III [Paenibacillus assamensis].	30.31	706	435	19	1	661	1	694	3e-81	284
tr:A0A0C7SIW7_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.68	664	361	24	3	631	5	617	3e-81	283
rs:WP_000779850	DNA topoisomerase III [Streptococcus agalactiae].	33.11	601	355	13	1	587	1	568	3e-81	280
rs:WP_004342332	DNA topoisomerase III [Prevotella buccae].	30.88	625	395	13	1	603	1	610	3e-81	283
rs:WP_021322604	MULTISPECIES: DNA topoisomerase III [Geobacillus].	28.85	721	462	20	1	681	1	710	3e-81	284
rs:WP_034832080	DNA topoisomerase III [Endozoicomonas numazuensis].	31.24	589	370	13	1	560	1	583	3e-81	282
rs:WP_032567317	DNA topoisomerase I [Bacteroides fragilis].	30.80	711	434	23	1	684	1	680	3e-81	283
tr:A0A098F5K3_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.04	646	396	18	3	623	5	632	3e-81	282
rs:WP_042083422	DNA topoisomerase III [Escherichia coli].	31.86	612	376	18	1	581	1	602	3e-81	282
tr:X6SVQ9_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.95	601	356	13	1	587	1	568	3e-81	280
rs:WP_043823102	DNA topoisomerase III [Aeromonas veronii].	29.91	652	415	13	1	624	1	638	3e-81	282
rs:WP_019105610	DNA topoisomerase III [Pantoea ananatis].	28.79	660	426	12	1	629	1	647	3e-81	283
rs:WP_024483847	DNA topoisomerase III [Serratia fonticola].	29.82	607	393	13	1	581	1	600	3e-81	283
rs:WP_026584089	DNA topoisomerase III [Bacillus sp. J33].	30.36	672	412	17	3	654	4	639	3e-81	283
rs:WP_033572488	DNA topoisomerase I [Bacteroides sp. UW].	28.35	695	461	15	1	676	1	677	3e-81	283
tr:A0A0C7IWU1_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.68	664	361	24	3	631	5	617	3e-81	283
rs:WP_046159436	DNA topoisomerase [Streptococcus dysgalactiae].	33.89	602	349	15	1	587	1	568	3e-81	280
rs:WP_024589767	MULTISPECIES: DNA topoisomerase III [Pseudoalteromonas].	31.76	614	373	12	1	579	1	603	3e-81	282
rs:WP_002498569	DNA topoisomerase III [Staphylococcus epidermidis].	33.81	633	371	20	3	615	4	608	3e-81	284
rs:WP_003329635	DNA topoisomerase III [Bacillus azotoformans].	32.62	656	391	20	3	627	5	640	3e-81	284
tr:D4LXB5_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.36	660	393	20	3	627	4	638	3e-81	284
rs:WP_033135309	DNA topoisomerase III [Aeromonas sp. 4287D].	31.56	621	390	14	1	593	1	614	3e-81	282
rs:WP_004026788	DNA topoisomerase III [Ureaplasma urealyticum].	32.83	597	369	15	1	590	1	572	3e-81	280
rs:WP_007139586	DNA topoisomerase [Flavobacterium frigoris].	31.22	711	436	20	1	684	1	685	3e-81	283
rs:WP_002596245	DNA topoisomerase III [[Clostridium] clostridioforme].	30.11	714	432	22	1	680	1	681	3e-81	283
rs:WP_008653004	DNA topoisomerase I [Bacteroides sp. 3_1_33FAA].	28.69	697	458	15	1	677	1	678	3e-81	283
rs:WP_018879179	hypothetical protein, partial [Thioalkalivibrio sp. ALE9].	28.39	701	424	17	41	670	3	696	3e-81	284
tr:A0A070TKB5_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.89	641	398	19	3	608	1	631	3e-81	282
rs:WP_024603831	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	31.92	614	372	12	1	579	1	603	3e-81	282
rs:WP_025729328	DNA topoisomerase III [Bacillus ginsengihumi].	30.56	661	402	16	3	646	4	624	3e-81	283
rs:WP_002475810	DNA topoisomerase III [Staphylococcus epidermidis].	34.28	633	368	22	3	615	4	608	3e-81	283
rs:WP_000838490	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	3e-81	283
rs:WP_044551747	DNA topoisomerase III [Serratia liquefaciens].	31.75	611	378	18	1	581	1	602	3e-81	282
gp:CP010941_2189	DNA topoisomerase III [Staphylococcus aureus]	32.70	636	374	18	3	615	4	608	4e-81	283
rs:WP_012602298	DNA topoisomerase III [Escherichia coli].	31.16	613	379	18	1	581	20	621	4e-81	283
rs:WP_010197614	DNA topoisomerase III [Bacillus sp. m3-13].	32.57	651	397	19	3	627	5	639	4e-81	284
rs:WP_013617264	DNA topoisomerase III [Bacteroides salanitronis].	29.87	703	406	17	1	630	1	689	4e-81	283
rs:WP_010846535	DNA topoisomerase III [Xenorhabdus nematophila].	29.64	641	406	14	1	614	1	623	4e-81	282
rs:WP_045168253	DNA topoisomerase I [Prevotella intermedia].	31.29	719	437	24	1	684	1	697	4e-81	283
rs:WP_014791711	DNA topoisomerase [Ornithobacterium rhinotracheale].	31.95	698	428	20	1	673	1	676	4e-81	283
rs:WP_010557793	DNA topoisomerase III [Pseudoalteromonas marina].	32.62	604	367	15	1	574	1	594	4e-81	282
rs:WP_020846019	DNA topoisomerase III [Salmonella bongori].	31.03	609	389	12	1	587	1	600	4e-81	281
rs:WP_008664059	DNA topoisomerase III [Bacteroides sp. 4_1_36].	30.71	648	395	13	1	603	1	639	4e-81	284
tr:A0A0C7RF12_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.68	664	361	24	3	631	5	617	4e-81	283
tr:A0A0C7HMD1_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.68	664	361	24	3	631	5	617	4e-81	283
rs:WP_001235823	DNA topoisomerase III [Escherichia coli].	31.70	612	377	18	1	581	1	602	4e-81	282
rs:WP_000838509	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	4e-81	283
rs:WP_039771836	DNA topoisomerase III [Clostridium diolis].	33.18	657	381	22	3	627	5	635	4e-81	284
rs:WP_043000912	MULTISPECIES: DNA topoisomerase III [Citrobacter].	31.20	609	384	15	1	581	1	602	4e-81	282
tr:G2AVN2_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.89	641	398	19	3	608	1	631	4e-81	282
rs:WP_001235824	MULTISPECIES: DNA topoisomerase III [Escherichia].	31.70	612	377	18	1	581	1	602	4e-81	282
rs:WP_009535407	DNA topoisomerase III [Oribacterium parvum].	34.21	605	339	16	1	585	1	566	4e-81	280
rs:WP_038141933	DNA topoisomerase III [Thiothrix lacustris].	28.74	675	406	17	3	615	2	663	4e-81	283
rs:WP_044467849	DNA topoisomerase III [Bacteroides uniformis].	30.71	648	395	13	1	603	1	639	4e-81	284
rs:WP_025760919	DNA topoisomerase III [Shigella flexneri].	31.10	643	398	19	1	608	1	633	4e-81	282
rs:WP_001573525	DNA topoisomerase 3 [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	4e-81	283
rs:WP_002457943	DNA topoisomerase III [Staphylococcus epidermidis].	34.28	633	368	22	3	615	4	608	4e-81	283
rs:WP_002494147	DNA topoisomerase III [Staphylococcus epidermidis].	33.81	633	371	20	3	615	4	608	4e-81	283
tr:A0A0A8VWD1_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.68	664	361	24	3	631	5	617	4e-81	283
rs:WP_017382134	DNA topoisomerase III [Paenisporosarcina sp. TG-14].	31.25	656	393	22	3	627	5	633	4e-81	284
rs:WP_038669482	DNA topoisomerase III, partial [Sodalis praecaptivus].	30.32	620	375	15	1	581	1	602	4e-81	281
rs:WP_035425603	DNA topoisomerase III [Bacillus sp. L1(2012)].	30.54	717	446	20	1	676	1	706	4e-81	284
rs:WP_007845711	DNA topoisomerase I [Bacteroides dorei].	28.16	696	463	14	1	677	1	678	4e-81	283
rs:WP_002447325	DNA topoisomerase III [Staphylococcus epidermidis].	34.28	633	368	22	3	615	4	608	4e-81	283
rs:WP_002496109	DNA topoisomerase III [Staphylococcus epidermidis].	33.81	633	371	20	3	615	4	608	4e-81	283
rs:WP_031887564	DNA topoisomerase III, partial [Staphylococcus aureus].	32.91	635	372	18	3	614	4	607	4e-81	281
rs:WP_008752394	DNA topoisomerase III [Lachnoanaerobaculum saburreum].	34.18	588	338	15	1	571	1	556	4e-81	280
rs:WP_009071258	DNA topoisomerase [Metallosphaera yellowstonensis].	28.49	730	425	24	1	681	1	682	4e-81	283
rs:WP_007665430	DNA topoisomerase I [Bacteroides intestinalis].	29.10	701	450	19	1	677	1	678	4e-81	283
rs:WP_042650606	DNA topoisomerase III [Aeromonas media].	30.60	621	395	13	1	593	1	613	4e-81	282
rs:WP_000838475	DNA topoisomerase III [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	4e-81	283
rs:WP_007372580	DNA topoisomerase III [Kosakonia radicincitans].	29.46	662	425	13	1	633	1	649	4e-81	282
tr:A0A017RV88_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.92	705	423	20	3	671	5	681	4e-81	283
rs:WP_002477639	DNA topoisomerase 3 [Staphylococcus epidermidis].	33.81	633	371	20	3	615	4	608	4e-81	283
rs:WP_002503703	DNA topoisomerase III [Staphylococcus epidermidis].	33.97	633	370	20	3	615	4	608	4e-81	283
rs:WP_000838505	DNA topoisomerase 3 [Staphylococcus aureus].	33.02	642	364	18	3	615	4	608	4e-81	283
rs:WP_017941455	hypothetical protein, partial [Thioalkalivibrio sp. ALE6].	28.39	701	424	17	41	670	3	696	4e-81	283
rs:WP_011839989	DNA topoisomerase III [Shewanella baltica].	31.54	669	410	18	1	640	1	650	4e-81	283
rs:WP_020977494	DNA topoisomerase 3 [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	5e-81	283
rs:WP_019584476	hypothetical protein, partial [Thioalkalivibrio sp. ALE16].	28.39	701	424	17	41	670	3	696	5e-81	283
rs:WP_022072241	DNA topoisomerase III [Clostridium bartlettii CAG:1329].	34.04	661	357	26	3	631	5	618	5e-81	283
rs:WP_040206221	MULTISPECIES: DNA topoisomerase III [Bacillus].	32.82	652	393	19	3	627	5	638	5e-81	284
rs:WP_032121230	DNA topoisomerase III [Clostridium sp. LF2].	31.72	640	386	20	3	615	5	620	5e-81	284
rs:WP_011255049	DNA topoisomerase [Aromatoleum aromaticum].	30.92	663	391	17	1	615	1	644	5e-81	283
rs:WP_042864792	DNA topoisomerase III [Aeromonas hydrophila].	30.73	628	399	14	1	600	1	620	5e-81	282
rs:WP_006268556	DNA topoisomerase [Streptococcus constellatus].	34.67	600	347	16	1	587	1	568	5e-81	280
rs:WP_005332660	DNA topoisomerase III [Aeromonas media].	30.43	621	396	13	1	593	1	613	5e-81	282
rs:WP_004346762	DNA topoisomerase III [Prevotella buccae].	30.88	625	395	14	1	603	1	610	5e-81	283
rs:WP_000838488	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	5e-81	283
rs:WP_032845637	DNA topoisomerase I [Bacteroides ovatus].	29.90	709	439	20	1	678	1	682	5e-81	283
rs:WP_046059419	DNA topoisomerase III [Clostridium sp. IBUN22A].	32.44	632	386	16	3	615	5	614	5e-81	283
rs:WP_039041035	DNA topoisomerase III [Aeromonas caviae].	30.78	627	398	14	1	599	1	619	5e-81	282
rs:WP_009461692	hypothetical protein [Lachnospiraceae bacterium 2_1_46FAA].	29.21	719	446	23	1	687	1	688	5e-81	283
rs:WP_040062870	DNA topoisomerase III [Escherichia coli].	31.70	612	377	18	1	581	1	602	5e-81	282
rs:WP_035663412	DNA topoisomerase III [Bacillus akibai].	31.07	634	399	17	3	615	5	621	5e-81	283
rs:WP_026563023	DNA topoisomerase III [Bacillus sp. J37].	32.87	654	387	22	3	627	5	635	5e-81	283
rs:WP_000838506	DNA topoisomerase 3 [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	5e-81	283
rs:WP_012017079	DNA topoisomerase III [Enterobacter sp. 638].	31.18	603	378	16	1	574	1	595	5e-81	281
rs:WP_042197545	DNA topoisomerase III [Escherichia coli].	30.21	652	401	16	1	616	1	634	5e-81	283
rs:WP_047211734	DNA topoisomerase III [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	5e-81	283
rs:WP_014620938	DNA topoisomerase III [Shewanella baltica].	31.31	674	405	18	1	640	1	650	5e-81	283
gpu:CP011642_4511	DNA topoisomerase III [Serratia marcescens]	31.10	611	382	17	1	581	1	602	5e-81	281
rs:WP_034125070	DNA topoisomerase III [Peptococcaceae bacterium BICA1-7].	30.21	705	446	19	3	678	7	694	5e-81	283
tr:A0A029LLV7_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.80	610	375	18	3	581	1	600	5e-81	281
rs:WP_010675967	DNA topoisomerase III [Aeromonas caviae].	30.84	629	399	14	1	601	1	621	5e-81	282
rs:WP_007411728	DNA topoisomerase III [Prevotella sp. MSX73].	30.88	625	395	14	1	603	1	610	5e-81	283
rs:WP_004329672	DNA topoisomerase I [Alistipes putredinis].	29.51	698	451	19	1	677	1	678	5e-81	283
rs:WP_022508538	DNA topoisomerase III [Bacteroides vulgatus CAG:6].	29.33	716	410	18	1	629	1	707	5e-81	283
rs:WP_005845872	DNA topoisomerase III [Bacteroides vulgatus].	29.33	716	410	18	1	629	1	707	5e-81	283
rs:WP_006525975	DNA topoisomerase [Solobacterium moorei].	34.11	598	353	13	1	587	1	568	5e-81	280
rs:WP_013333796	DNA topoisomerase III [Halomonas elongata].	28.70	648	409	15	2	614	3	632	5e-81	282
rs:WP_026630256	DNA topoisomerase III [Dyadobacter alkalitolerans].	30.00	710	425	20	1	661	1	687	5e-81	283
rs:WP_016648539	DNA topoisomerase III [Facklamia hominis].	33.17	597	367	14	1	590	1	572	5e-81	280
rs:WP_029378515	DNA topoisomerase III [Staphylococcus xylosus].	33.60	631	376	17	3	615	4	609	5e-81	283
rs:WP_032131825	DNA topoisomerase I [Weeksella sp. FF8].	31.59	706	426	21	1	677	1	678	5e-81	283
rs:WP_012160000	DNA topoisomerase III [Alkaliphilus oremlandii].	31.65	714	435	19	2	678	3	700	5e-81	283
rs:WP_002597337	DNA topoisomerase III [Clostridium colicanis].	33.54	656	380	24	3	627	5	635	5e-81	283
rs:WP_000838489	DNA topoisomerase 3 [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	5e-81	283
rs:WP_009221186	DNA topoisomerase III [Lachnospiraceae oral taxon 107].	34.35	591	333	16	1	571	1	556	5e-81	280
tr:R6E059_9BACE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:CDA83657.1};	31.25	624	384	13	1	588	1	615	5e-81	283
rs:WP_014195908	MULTISPECIES: DNA topoisomerase III [Geobacillus].	28.57	721	464	19	1	681	1	710	5e-81	283
rs:WP_025883360	DNA topoisomerase I [Porphyromonas uenonis].	31.44	703	414	23	4	673	5	672	5e-81	283
rs:WP_016271901	DNA topoisomerase III [Bacteroides vulgatus].	30.66	711	436	22	1	684	1	681	6e-81	283
rs:WP_007653064	DNA topoisomerase I [Parabacteroides goldsteinii].	29.12	697	453	19	1	676	1	677	6e-81	283
rs:WP_005356359	DNA topoisomerase III [Aeromonas veronii].	30.00	650	413	13	1	622	1	636	6e-81	281
rs:WP_044899422	DNA topoisomerase III [Aeribacillus pallidus].	29.26	721	461	20	1	682	1	711	6e-81	283
tr:A0A0C7NXC2_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.53	664	362	24	3	631	5	617	6e-81	283
rs:WP_044290852	DNA topoisomerase III [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	6e-81	283
tr:A0A0C7RVR1_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.68	664	361	24	3	631	5	617	6e-81	283
tr:A0A0C7GPW0_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.53	667	358	24	3	631	5	617	6e-81	283
rs:WP_009334925	DNA topoisomerase III [Bacillus sp. 2_A_57_CT2].	29.79	678	408	20	3	654	4	639	6e-81	283
rs:WP_015548008	DNA topoisomerase III, bacteria and conjugative plasmid [Alistipes shahii].	30.75	709	437	21	1	684	1	680	6e-81	283
rs:WP_045407416	DNA topoisomerase III [Vibrio jasicida].	29.32	706	424	22	1	659	1	678	6e-81	283
rs:WP_006573250	DNA topoisomerase III [Pseudoflavonifractor capillosus].	30.62	712	431	22	1	680	1	681	6e-81	283
rs:WP_020373506	hypothetical protein [Sulfobacillus thermosulfidooxidans].	29.02	703	435	18	1	675	1	667	6e-81	282
rs:WP_034440685	DNA topoisomerase [Clostridiales bacterium S5-A11].	33.17	597	367	15	1	590	1	572	6e-81	280
rs:WP_000838487	DNA topoisomerase 3 [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	6e-81	283
rs:WP_044731386	DNA topoisomerase III [Geobacillus kaustophilus].	29.29	717	464	20	1	681	1	710	6e-81	283
tr:W1WMJ5_9ZZZZ	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ETJ17674.1};	33.89	661	358	25	3	631	5	618	6e-81	283
tr:A0A0C7SIK7_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.44	669	356	24	3	631	5	617	6e-81	283
rs:WP_036520289	DNA topoisomerase III [Nitrincola sp. A-D6].	31.08	621	374	16	1	581	1	607	6e-81	281
rs:WP_033859118	DNA topoisomerase 3 [Staphylococcus aureus].	33.02	636	372	18	3	615	4	608	6e-81	283
rs:WP_037419974	DNA topoisomerase III, partial [Serratia grimesii].	31.59	611	379	18	1	581	1	602	6e-81	281
rs:WP_039212971	DNA topoisomerase III [Aeromonas hydrophila].	29.91	652	414	16	1	624	1	637	6e-81	281
rs:WP_038877225	DNA topoisomerase III [Serratia marcescens].	31.10	611	382	17	1	581	1	602	6e-81	281
rs:WP_032581312	DNA topoisomerase I [Bacteroides fragilis].	28.16	696	463	14	1	677	1	678	6e-81	283
sp:TOP3_STAA8	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	32.86	636	373	18	3	615	4	608	6e-81	283
rs:WP_044359601	DNA topoisomerase III [Staphylococcus microti].	31.26	627	395	16	3	615	4	608	6e-81	283
rs:WP_024608331	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	31.83	622	362	13	1	579	1	603	6e-81	281
rs:WP_027702332	DNA topoisomerase III [[Clostridium] mangenotii].	32.47	656	375	23	3	631	5	619	6e-81	283
rs:WP_038354286	DNA topoisomerase III [Escherichia sp. HT073016].	30.82	610	385	16	1	581	1	602	6e-81	281
rs:WP_039512817	DNA topoisomerase III [Pectobacterium carotovorum].	30.02	613	388	13	1	581	1	604	6e-81	282
rs:WP_008653364	DNA topoisomerase I [Bacteroides sp. 3_1_33FAA].	30.18	709	442	20	1	684	1	681	6e-81	283
rs:WP_019117888	DNA topoisomerase III [Anaerococcus obesiensis].	33.61	598	356	14	1	587	1	568	6e-81	279
rs:WP_001516287	MULTISPECIES: DNA topoisomerase III [Escherichia].	31.03	609	385	15	1	581	1	602	6e-81	281
rs:WP_038812454	topoisomerase [Staphylococcus epidermidis].	33.65	633	372	20	3	615	4	608	6e-81	283
rs:WP_036764969	DNA topoisomerase [Peptostreptococcus sp. MV1].	33.89	599	353	15	1	587	1	568	6e-81	279
rs:WP_016234421	DNA topoisomerase III [Escherichia coli].	31.37	612	379	17	1	581	1	602	7e-81	281
rs:WP_012679621	DNA topoisomerase III [Streptococcus equi].	34.00	600	349	14	3	588	4	570	7e-81	279
rs:WP_040289620	DNA topoisomerase III, partial [Bilophila wadsworthia].	30.29	657	410	18	1	627	1	639	7e-81	281
rs:WP_043142985	DNA topoisomerase III [Serratia marcescens].	31.26	611	381	17	1	581	1	602	7e-81	281
rs:WP_002491551	DNA topoisomerase III [Staphylococcus epidermidis].	34.28	633	368	22	3	615	4	608	7e-81	283
rs:WP_020999707	DNA topoisomerase III [Streptococcus anginosus].	33.72	599	354	15	1	587	1	568	7e-81	279
rs:WP_005339851	DNA topoisomerase III [Aeromonas veronii].	29.60	652	417	13	1	624	1	638	7e-81	281
rs:WP_033861666	DNA topoisomerase III, partial [Staphylococcus aureus].	32.70	636	374	18	3	615	4	608	7e-81	281
rs:WP_016240855	DNA topoisomerase III [Escherichia coli].	31.37	612	379	17	1	581	1	602	7e-81	281
rs:WP_006032728	DNA topoisomerase III [Moritella sp. PE36].	31.72	618	377	18	1	582	1	609	7e-81	281
rs:WP_022269543	DNA topoisomerase [Firmicutes bacterium CAG:424].	32.26	654	390	19	3	627	4	633	7e-81	283
tr:A0A0A6ZS57_SHIDY	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.70	612	375	19	1	580	20	620	7e-81	281
rs:WP_025303086	DNA topoisomerase III [Serratia marcescens].	31.26	611	381	17	1	581	1	602	7e-81	281
rs:WP_040070032	DNA topoisomerase III [Aeromonas veronii].	29.82	664	400	17	1	624	1	638	7e-81	281
rs:WP_015869774	DNA topoisomerase III [Edwardsiella ictaluri].	29.23	691	431	20	1	658	1	666	7e-81	282
rs:WP_036941675	DNA topoisomerase III [Providencia stuartii].	29.39	677	426	16	1	639	1	663	7e-81	282
tr:W4PIV4_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE19069.1};	31.85	653	363	20	1	588	70	705	7e-81	286
rs:WP_047199200	DNA topoisomerase [Streptococcus agalactiae].	34.28	601	344	16	3	587	5	570	7e-81	279
tr:G5GJE6_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.28	710	437	20	2	683	16	695	7e-81	283
rs:WP_041691717	hypothetical protein, partial [Eggerthella lenta].	29.31	713	439	20	3	667	4	699	7e-81	283
rs:WP_018878671	hypothetical protein, partial [Thioalkalivibrio sp. ALE28].	28.53	701	423	17	41	670	3	696	7e-81	283
rs:WP_002499566	DNA topoisomerase III [Staphylococcus epidermidis].	34.28	633	368	22	3	615	4	608	7e-81	283
rs:WP_046790153	DNA topoisomerase III [Salinicoccus halodurans].	31.65	654	396	21	3	627	5	636	7e-81	283
rs:WP_043084421	DNA topoisomerase III [Pluralibacter gergoviae].	31.52	606	372	19	1	574	1	595	7e-81	281
rs:WP_016270904	DNA topoisomerase III [Bacteroides vulgatus].	29.29	717	411	18	1	630	1	708	7e-81	283
rs:WP_032585698	DNA topoisomerase I [Bacteroides fragilis].	29.51	698	451	19	1	677	1	678	7e-81	282
rs:WP_046463202	DNA topoisomerase III [Staphylococcus aureus].	33.18	642	363	18	3	615	4	608	7e-81	283
rs:WP_041979771	DNA topoisomerase III [Xenorhabdus nematophila].	30.40	648	395	17	1	614	1	626	7e-81	281
rs:WP_033121926	DNA topoisomerase III [Oscillibacter sp. ER4].	29.80	651	400	17	1	626	1	619	8e-81	282
rs:WP_041035424	DNA topoisomerase III [Serratia marcescens].	31.26	611	381	17	1	581	1	602	8e-81	281
rs:WP_029099989	DNA topoisomerase III [Brevibacillus thermoruber].	29.26	721	461	20	1	682	1	711	8e-81	283
rs:WP_009644045	DNA topoisomerase III [Mogibacterium sp. CM50].	34.63	592	344	15	1	580	1	561	8e-81	279
rs:WP_016418561	hypothetical protein [Halomonas anticariensis].	30.38	678	418	16	2	641	3	664	8e-81	282
rs:WP_016276696	DNA topoisomerase III [Bacteroides massiliensis].	29.04	699	453	18	1	677	1	678	8e-81	282
rs:WP_042987762	DNA topoisomerase I [Bacteroides fragilis].	29.37	698	452	19	1	677	1	678	8e-81	282
rs:WP_033647606	DNA topoisomerase III [Serratia marcescens].	31.10	611	382	17	1	581	1	602	8e-81	281
rs:WP_036108821	DNA topoisomerase III, partial [Mangrovibacter sp. MFB070].	30.51	613	383	17	1	581	1	602	8e-81	281
rs:WP_000838507	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	8e-81	283
rs:WP_039422551	DNA topoisomerase I [Porphyromonas gulae].	30.46	719	443	24	1	684	1	697	8e-81	283
rs:WP_009510834	DNA topoisomerase [Opitutaceae bacterium TAV5].	30.23	665	402	16	1	624	1	644	8e-81	285
rs:WP_004586877	DNA topoisomerase III [Pseudoalteromonas agarivorans].	31.60	614	376	15	1	580	1	604	8e-81	281
rs:WP_026713482	DNA topoisomerase I [Flavobacterium daejeonense].	32.68	716	415	26	1	682	1	683	8e-81	282
rs:WP_022461978	DNA topoisomerase [Blautia sp. CAG:37].	32.93	659	385	22	3	627	4	639	8e-81	283
rs:WP_014779928	DNA topoisomerase III [Thiocystis violascens].	26.81	731	470	17	3	680	4	722	8e-81	286
rs:WP_021967732	MULTISPECIES: DNA topoisomerase III [Bacteroides].	28.47	720	415	15	1	629	1	711	8e-81	283
rs:WP_015267011	topoisomerase IA [Echinicola vietnamensis].	31.82	704	420	23	1	673	1	675	8e-81	282
rs:WP_007516585	DNA topoisomerase III [Streptococcus tigurinus].	34.33	603	345	18	1	587	1	568	8e-81	279
rs:WP_036850011	DNA topoisomerase I [Porphyromonas cangingivalis].	30.58	726	433	24	1	684	1	697	8e-81	283
rs:WP_009906449	DNA topoisomerase III [Peptoclostridium difficile].	33.44	598	357	13	1	587	1	568	8e-81	279
rs:WP_016248644	MULTISPECIES: DNA topoisomerase III [Escherichia].	31.03	609	385	15	1	581	1	602	8e-81	281
rs:WP_001235825	DNA topoisomerase III [Escherichia coli].	31.03	609	385	15	1	581	1	602	8e-81	281
rs:WP_045969231	DNA topoisomerase III [Xenorhabdus doucetiae].	30.48	643	402	16	1	614	1	627	8e-81	281
rs:WP_014298481	DNA topoisomerase I [Bacteroides fragilis].	28.16	696	463	14	1	677	1	678	8e-81	282
rs:WP_007659952	DNA topoisomerase III [Bacteroides intestinalis].	28.47	720	415	15	1	629	1	711	8e-81	283
rs:WP_034669318	MULTISPECIES: DNA topoisomerase I [Chryseobacterium].	30.96	701	429	20	1	673	1	674	8e-81	282
rs:WP_031910301	DNA topoisomerase III, partial [Staphylococcus aureus].	32.70	636	374	18	3	615	4	608	8e-81	282
rs:WP_006740590	DNA topoisomerase III [Streptococcus urinalis].	33.28	598	365	16	1	590	1	572	9e-81	279
rs:WP_042880354	DNA topoisomerase III [Aeromonas sp. ZOR0002].	30.78	627	398	14	1	599	1	619	9e-81	281
rs:WP_003386221	DNA topoisomerase III [Brevibacillus borstelensis].	29.64	722	461	17	1	684	1	713	9e-81	283
rs:WP_006190863	DNA topoisomerase 3 [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	9e-81	283
rs:WP_029730844	DNA topoisomerase III [Dorea sp. AGR2135].	29.45	713	449	19	3	687	5	691	9e-81	282
rs:WP_009537904	MULTISPECIES: DNA topoisomerase [Lachnospiraceae].	34.28	598	352	14	1	587	1	568	9e-81	279
rs:WP_006906961	DNA topoisomerase [Shuttleworthia satelles].	33.39	602	352	15	1	587	1	568	9e-81	279
rs:WP_041416793	DNA topoisomerase III [Shewanella sp. MR-7].	31.25	656	391	15	1	603	1	649	9e-81	282
rs:WP_018666382	DNA topoisomerase III [Bacteroides gallinarum].	30.22	675	396	16	1	626	1	649	9e-81	283
rs:WP_042371118	DNA topoisomerase III [Bacteroidaceae bacterium MS4].	31.72	599	386	12	1	588	1	587	9e-81	282
rs:WP_016224225	DNA topoisomerase III [Lachnospiraceae bacterium 3-2].	31.76	680	387	20	3	627	4	661	9e-81	283
tr:A0A0A8NYT3_XENNE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.40	648	395	17	1	614	7	632	9e-81	281
rs:WP_032214543	DNA topoisomerase III [Escherichia coli].	30.87	609	390	12	1	587	1	600	9e-81	280
rs:WP_045522780	DNA topoisomerase III [Aeromonas caviae].	30.78	627	398	14	1	599	1	619	9e-81	281
rs:WP_003034176	DNA topoisomerase III [Streptococcus anginosus].	34.58	590	339	15	1	576	1	557	9e-81	279
rs:WP_044327842	DNA topoisomerase III [Citrobacter amalonaticus].	31.20	609	384	15	1	581	1	602	9e-81	281
rs:WP_012765573	MULTISPECIES: DNA topoisomerase III [Dickeya].	30.05	619	378	18	1	581	1	602	9e-81	281
rs:WP_020366414	DNA topoisomerase III [Staphylococcus epidermidis].	34.28	633	368	22	3	615	4	608	9e-81	283
rs:WP_036889583	DNA topoisomerase I [Porphyromonas crevioricanis].	30.73	716	445	21	1	684	1	697	9e-81	282
tr:F9GN99_HAEHA	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.43	626	367	19	1	583	1	613	9e-81	281
rs:WP_046724002	DNA topoisomerase III [Paenibacillus durus].	30.52	639	385	16	3	615	4	609	1e-80	283
rs:WP_000838497	DNA topoisomerase 3 [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	1e-80	282
rs:WP_010538243	DNA topoisomerase I [Bacteroides faecis].	30.39	714	433	24	1	684	1	680	1e-80	282
rs:WP_032587100	DNA topoisomerase I [Bacteroides fragilis].	29.37	698	452	19	1	677	1	678	1e-80	282
rs:WP_002470665	DNA topoisomerase III [Staphylococcus epidermidis].	33.81	633	371	20	3	615	4	608	1e-80	282
rs:WP_009124378	DNA topoisomerase III [Bacteroides fluxus].	30.57	651	394	15	1	603	1	641	1e-80	283
rs:WP_011573665	DNA topoisomerase III [Pseudoalteromonas atlantica].	30.68	616	388	12	1	581	1	612	1e-80	281
tr:W0HXD6_9ENTR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.32	620	375	15	1	581	1	602	1e-80	281
rs:WP_013145263	DNA topoisomerase III [Geobacillus sp. C56-T3].	29.15	717	465	20	1	681	1	710	1e-80	283
tr:A0A068QPA2_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.48	643	402	16	1	614	7	633	1e-80	281
tr:A0A071LW77_9ENTR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.51	613	383	17	1	581	1	602	1e-80	281
rs:WP_046588404	DNA topoisomerase III [Bacillus sp. SA1-12].	32.62	653	393	21	3	627	5	638	1e-80	283
rs:WP_010365922	DNA topoisomerase III [Pseudoalteromonas citrea].	32.32	591	361	10	1	560	1	583	1e-80	280
tr:J2T8C6_9FLAO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJL74342.1};	30.96	701	429	20	1	673	25	698	1e-80	283
rs:WP_043153916	DNA topoisomerase III [Aeromonas sp. HZM].	30.30	627	401	13	1	599	1	619	1e-80	281
rs:WP_032587146	DNA topoisomerase I [Bacteroides fragilis].	30.52	711	437	22	1	684	1	681	1e-80	282
rs:WP_037315920	DNA topoisomerase I [Salegentibacter sp. Hel_I_6].	32.11	707	431	21	1	682	1	683	1e-80	282
rs:WP_031874900	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	1e-80	282
rs:WP_023604926	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	1e-80	282
rs:WP_004819943	DNA topoisomerase III [Peptoniphilus indolicus].	33.39	599	356	15	1	587	1	568	1e-80	279
rs:WP_021630736	DNA topoisomerase [Clostridium sp. ATCC BAA-442].	27.72	707	460	20	2	687	3	679	1e-80	281
rs:WP_000838493	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	1e-80	282
rs:WP_024990781	DNA topoisomerase I [Prevotella marshii].	30.80	711	434	23	1	684	1	680	1e-80	282
rs:WP_032543297	DNA topoisomerase I [Bacteroides fragilis].	28.20	695	462	15	1	676	1	677	1e-80	282
rs:WP_017465080	DNA topoisomerase III [Staphylococcus epidermidis].	33.81	633	371	20	3	615	4	608	1e-80	282
rs:WP_021034374	DNA topoisomerase III [Haemophilus influenzae].	32.37	624	370	19	1	583	1	613	1e-80	281
rs:WP_006704071	DNA topoisomerase III [Candidatus Regiella insecticola].	31.59	630	379	19	1	589	1	619	1e-80	280
rs:WP_022151843	DNA topoisomerase [Lachnospiraceae bacterium CAG:215].	31.14	668	397	20	3	627	4	651	1e-80	283
rs:WP_033741875	DNA topoisomerase III [Pantoea stewartii].	30.78	627	363	19	1	581	1	602	1e-80	280
rs:WP_024984278	DNA topoisomerase III [Brevibacillus borstelensis].	29.64	722	461	17	1	684	1	713	1e-80	282
rs:WP_005634570	DNA topoisomerase III [Haemophilus haemolyticus].	32.37	624	370	19	1	583	1	613	1e-80	281
rs:WP_033020754	DNA topoisomerase III [Geobacillus sp. G1w1].	29.15	717	465	20	1	681	1	710	1e-80	282
rs:WP_024739084	DNA topoisomerase III [Clostridiales bacterium VE202-16].	29.43	700	439	19	1	671	1	674	1e-80	282
rs:WP_009389013	DNA topoisomerase [Capnocytophaga sp. oral taxon 329].	31.37	714	422	25	1	675	1	685	1e-80	282
rs:WP_031900030	DNA topoisomerase III, partial [Staphylococcus aureus].	32.70	636	374	18	3	615	4	608	1e-80	282
rs:WP_000115174	DNA topoisomerase III [Bacillus thuringiensis].	30.25	724	437	20	3	680	4	705	1e-80	282
rs:WP_029304903	DNA topoisomerase III [Aeromonas hydrophila].	30.05	659	404	18	1	624	1	637	1e-80	281
rs:WP_024945198	DNA topoisomerase III [Aeromonas hydrophila].	30.06	652	413	16	1	624	1	637	1e-80	281
tr:Q0HWK8_SHESR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.25	656	391	15	1	603	26	674	1e-80	283
rs:WP_002485898	DNA topoisomerase III [Staphylococcus epidermidis].	33.81	633	371	20	3	615	4	608	1e-80	282
rs:WP_000838481	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	1e-80	282
rs:WP_021672576	DNA topoisomerase [Prevotella sp. F0091].	30.64	718	443	22	1	684	1	697	1e-80	282
rs:WP_011666398	DNA topoisomerase III [Bordetella pertussis].	30.26	651	409	15	1	614	1	643	1e-80	281
rs:WP_011965390	DNA topoisomerase III [Bacteroides vulgatus].	29.29	717	411	18	1	630	1	708	1e-80	282
tr:A0A0A5MQ36_AERCA	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.78	627	398	14	1	599	1	619	1e-80	281
rs:WP_032463650	DNA topoisomerase III [Streptococcus pyogenes].	33.00	597	368	15	1	590	1	572	1e-80	278
tr:A0A0B6X433_XENBV	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.23	645	399	15	1	614	7	631	1e-80	281
rs:WP_043147568	DNA topoisomerase III [Serratia marcescens].	31.10	611	382	17	1	581	1	602	1e-80	280
rs:WP_022628548	DNA topoisomerase III [Bacillus marmarensis].	31.48	594	380	12	1	573	1	588	1e-80	282
rs:WP_004366614	DNA topoisomerase I [Prevotella nigrescens].	30.88	719	440	23	1	684	1	697	1e-80	282
rs:WP_041211922	DNA topoisomerase III [Aeromonas caviae].	30.78	627	398	14	1	599	1	619	1e-80	281
rs:WP_000838498	DNA topoisomerase 3 [Staphylococcus aureus].	32.70	636	374	18	3	615	4	608	1e-80	282
rs:WP_013379324	DNA topoisomerase III [Eubacterium limosum].	32.07	633	391	15	3	615	7	620	1e-80	282
tr:A0A084YU57_9ENTR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.59	611	379	18	1	581	1	602	1e-80	282
rs:WP_000114570	DNA topoisomerase III [Bacillus cereus].	30.39	724	436	21	3	680	4	705	1e-80	282
rs:WP_012959749	DNA topoisomerase III [Bacillus pseudofirmus].	31.48	594	380	12	1	573	1	588	1e-80	282
rs:WP_003362991	DNA topoisomerase III [Clostridium botulinum].	31.69	669	405	23	3	638	5	654	1e-80	282
rs:WP_002489667	DNA topoisomerase 3 [Staphylococcus epidermidis].	33.81	633	371	20	3	615	4	608	1e-80	282
rs:WP_046336194	DNA topoisomerase III [Xenorhabdus bovienii].	30.23	645	399	15	1	614	1	625	1e-80	281
rs:WP_041123572	DNA topoisomerase III [Jeotgalibacillus alimentarius].	31.38	650	394	17	3	627	5	627	1e-80	282
rs:WP_017646113	DNA topoisomerase III [Streptococcus agalactiae].	33.39	611	340	17	1	587	1	568	1e-80	278
rs:WP_043132818	DNA topoisomerase III [Aeromonas media].	30.43	621	396	13	1	593	1	613	1e-80	281
sp:TOP3_STAES	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	33.81	633	371	20	3	615	4	608	1e-80	282
rs:WP_002981562	DNA topoisomerase [Chryseobacterium gleum].	29.51	698	452	17	1	678	1	678	1e-80	281
rs:WP_018948401	hypothetical protein, partial [Thioalkalivibrio sp. ALMg11].	29.75	706	408	21	41	670	3	696	1e-80	282
rs:WP_026624425	DNA topoisomerase [Eggerthia catenaformis].	34.28	598	352	14	1	587	1	568	1e-80	278
rs:WP_042594782	DNA topoisomerase III [Haemophilus influenzae].	31.73	624	374	18	1	583	1	613	1e-80	280
rs:WP_028773045	DNA topoisomerase III [Shewanella waksmanii].	31.38	631	389	17	1	594	1	624	1e-80	281
tr:A0A0C7LFG7_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.68	664	361	24	3	631	5	617	1e-80	282
rs:WP_028898404	DNA topoisomerase I [Prevotella sp. HUN102].	30.50	718	444	22	1	684	1	697	1e-80	282
rs:WP_012678206	DNA topoisomerase [Streptococcus equi].	33.33	600	355	15	1	587	1	568	1e-80	278
rs:WP_011272053	DNA topoisomerase III [Haemophilus influenzae].	31.73	624	374	18	1	583	1	613	1e-80	280
rs:WP_016273003	DNA topoisomerase III [Bacteroides uniformis].	30.56	648	396	13	1	603	1	639	1e-80	282
rs:WP_041086883	DNA topoisomerase III [Jeotgalibacillus soli Cunha et al. 2012].	31.66	657	395	20	3	627	5	639	1e-80	282
rs:WP_005421647	hypothetical protein [[Ruminococcus] obeum].	30.07	715	442	21	3	687	5	691	1e-80	281
rs:WP_019446465	DNA topoisomerase III [Aeromonas sp. 159].	30.21	652	413	14	1	624	1	638	1e-80	281
rs:WP_000838474	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	1e-80	282
rs:WP_039334584	DNA topoisomerase III [Pantoea rodasii].	31.70	612	363	19	1	574	1	595	2e-80	280
rs:WP_024932262	DNA topoisomerase III, partial [Clostridium botulinum].	31.74	671	402	24	3	638	5	654	2e-80	282
rs:WP_039678617	DNA topoisomerase III [Terrisporobacter othiniensis].	33.03	654	374	21	3	631	5	619	2e-80	282
rs:WP_012779890	DNA topoisomerase III [Dyadobacter fermentans].	29.90	699	436	19	1	661	1	683	2e-80	282
rs:WP_022415164	DNA topoisomerase [Dorea longicatena CAG:42].	31.35	689	390	19	3	627	4	673	2e-80	283
rs:WP_035587590	DNA topoisomerase III [Elizabethkingia anophelis].	30.62	712	444	18	1	678	1	696	2e-80	281
rs:WP_025271599	DNA topoisomerase [Streptococcus anginosus].	33.56	587	349	13	1	576	1	557	2e-80	278
rs:WP_031833533	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	2e-80	282
rs:WP_033851494	DNA topoisomerase III, partial [Staphylococcus aureus].	32.70	636	374	18	3	615	4	608	2e-80	281
rs:WP_043762485	DNA topoisomerase III [Aeromonas taiwanensis].	30.29	647	409	15	1	619	1	633	2e-80	280
rs:WP_012789015	DNA topoisomerase III [Chitinophaga pinensis].	29.67	701	436	17	1	660	1	685	2e-80	282
rs:WP_031832724	DNA topoisomerase 3 [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	2e-80	282
rs:WP_024379017	DNA topoisomerase [Streptococcus suis].	33.61	598	356	13	1	587	1	568	2e-80	278
rs:WP_016192491	DNA topoisomerase III [Erwinia tracheiphila].	32.37	621	361	21	1	581	1	602	2e-80	280
rs:WP_045331640	DNA topoisomerase III [Enterobacter cloacae].	30.96	604	386	12	1	582	1	595	2e-80	279
sp:TOP3_STAEQ	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	33.81	633	371	20	3	615	4	608	2e-80	282
rs:WP_036889351	DNA topoisomerase I [Porphyromonas crevioricanis].	31.08	711	433	24	1	676	1	689	2e-80	282
rs:WP_031906579	DNA topoisomerase 3 [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	2e-80	282
rs:WP_044394496	DNA topoisomerase III [Bacillus subterraneus].	30.75	657	407	15	3	646	4	625	2e-80	281
rs:WP_031911155	DNA topoisomerase 3 [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	2e-80	282
rs:WP_031902343	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	2e-80	282
rs:WP_004325469	DNA topoisomerase I [Bacteroides ovatus].	28.76	699	455	16	1	677	1	678	2e-80	281
rs:WP_002996062	MULTISPECIES: DNA topoisomerase [Bacteroidetes].	31.54	707	432	21	1	680	1	682	2e-80	281
rs:WP_029427372	DNA topoisomerase I [Bacteroides cellulosilyticus].	29.47	699	449	19	1	677	1	677	2e-80	281
rs:WP_005686905	DNA topoisomerase III [Haemophilus influenzae].	32.16	625	370	19	1	583	1	613	2e-80	280
rs:WP_034847279	DNA topoisomerase III [Elizabethkingia meningoseptica].	30.62	712	444	18	1	678	1	696	2e-80	281
rs:WP_009170744	DNA topoisomerase III [Clostridium sp. DL-VIII].	32.82	655	386	22	3	627	5	635	2e-80	282
rs:WP_045524421	DNA topoisomerase III [Bacillus niacini].	30.56	661	403	17	3	646	4	625	2e-80	281
rs:WP_011722818	DNA topoisomerase III [Clostridium novyi].	32.47	656	389	19	3	627	5	637	2e-80	282
rs:WP_033859739	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	2e-80	281
rs:WP_036880865	DNA topoisomerase III [Porphyromonas sp. COT-239 OH1446].	29.50	661	423	22	1	629	1	650	2e-80	281
rs:WP_042054821	DNA topoisomerase III [Aeromonas veronii].	30.31	650	415	13	1	624	1	638	2e-80	280
rs:WP_005341866	DNA topoisomerase III [Aeromonas veronii].	31.13	652	407	15	1	624	1	638	2e-80	280
rs:WP_032119053	DNA topoisomerase III [Clostridium sp. CL-2].	31.76	655	394	20	3	627	5	636	2e-80	282
rs:WP_040435932	DNA topoisomerase III [[Clostridium] hylemonae].	32.43	663	387	23	3	627	4	643	2e-80	282
rs:WP_039226428	DNA topoisomerase III [Clostridium novyi].	32.47	656	389	19	3	627	5	637	2e-80	282
rs:WP_000115175	DNA topoisomerase III [Bacillus thuringiensis].	29.57	717	451	18	3	680	4	705	2e-80	282
rs:WP_045039898	DNA topoisomerase III [Photobacterium iliopiscarium].	31.94	623	368	22	1	581	1	609	2e-80	280
rs:WP_031793812	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	2e-80	281
rs:WP_017926600	hypothetical protein, partial [Thioalkalivibrio sp. HL-Eb18].	28.25	701	425	17	41	670	3	696	2e-80	281
rs:WP_033025446	DNA topoisomerase III [Geobacillus sp. CAMR5420].	28.73	717	468	19	1	681	1	710	2e-80	282
rs:WP_007860969	MULTISPECIES: DNA topoisomerase III [Clostridiales].	30.79	669	391	19	3	627	4	644	2e-80	282
rs:WP_047050492	DNA topoisomerase III [Enterobacter aerogenes].	30.71	609	391	12	1	587	1	600	2e-80	279
sp:TOP3_STAA3	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	32.86	636	373	18	3	615	4	608	2e-80	281
rs:WP_042994340	DNA topoisomerase I [Bacteroides fragilis].	29.47	699	449	19	1	677	1	677	2e-80	281
rs:WP_002561001	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	30.80	711	434	23	1	684	1	680	2e-80	281
rs:WP_006255807	DNA topoisomerase I [Alloprevotella tannerae].	30.52	711	437	22	1	684	1	681	2e-80	281
rs:WP_031925301	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	2e-80	281
rs:WP_031921997	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	2e-80	281
rs:WP_002198656	DNA topoisomerase III [Bacillus cereus].	29.90	729	433	21	3	680	4	705	2e-80	281
rs:WP_042319450	DNA topoisomerase III [Citrobacter farmeri].	30.27	641	403	18	1	608	1	630	2e-80	280
rs:WP_035295670	DNA topoisomerase III, partial [Brevibacillus thermoruber].	29.37	715	456	20	1	676	1	705	2e-80	281
rs:WP_033634801	DNA topoisomerase III [Serratia marcescens].	31.10	611	382	17	1	581	1	602	2e-80	280
rs:WP_016927481	DNA topoisomerase III [Serratia marcescens].	31.10	611	382	17	1	581	1	602	2e-80	280
rs:WP_042031860	DNA topoisomerase III [Aeromonas jandaei].	29.52	664	402	17	1	624	1	638	2e-80	280
rs:WP_004326100	MULTISPECIES: DNA topoisomerase I [Bacteroides].	28.16	696	463	14	1	677	1	678	2e-80	281
rs:WP_025161293	DNA topoisomerase III [[Clostridium] bifermentans].	32.32	659	370	23	3	631	5	617	2e-80	281
rs:WP_019559093	hypothetical protein, partial [Thioalkalivibrio sp. ALE12].	28.39	701	424	17	41	670	3	696	2e-80	281
rs:WP_032461281	DNA topoisomerase [Streptococcus pyogenes].	34.44	601	343	16	3	587	5	570	2e-80	278
rs:WP_007883189	DNA topoisomerase III [Roseburia inulinivorans].	29.50	705	440	23	1	682	1	671	2e-80	281
rs:WP_031807777	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	2e-80	281
rs:WP_032459429	DNA topoisomerase [Streptococcus agalactiae].	34.28	601	344	16	3	587	5	570	2e-80	278
rs:WP_001996279	DNA topoisomerase III [Bacillus cereus].	30.11	714	441	21	3	675	5	701	2e-80	281
rs:WP_000838492	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	2e-80	281
rs:WP_031519835	DNA topoisomerase III [Cronobacter sp. 1383].	31.77	617	370	21	1	581	1	602	2e-80	280
rs:WP_017372945	DNA topoisomerase III [Enterobacteriaceae bacterium LSJC7].	31.99	619	366	20	1	581	1	602	2e-80	280
rs:WP_027631371	DNA topoisomerase III [Clostridium hydrogeniformans].	31.60	636	392	17	3	615	5	620	2e-80	282
rs:WP_041406328	DNA topoisomerase III, partial [Shewanella denitrificans].	31.10	643	396	17	1	603	1	636	2e-80	280
rs:WP_024397233	DNA topoisomerase [Streptococcus suis].	34.17	600	350	16	1	587	1	568	2e-80	278
rs:WP_005639112	DNA topoisomerase III [Haemophilus haemolyticus].	32.37	624	370	19	1	583	1	613	2e-80	280
rs:WP_002846237	DNA topoisomerase III [Peptostreptococcus anaerobius].	32.78	601	357	13	1	587	1	568	2e-80	278
rs:WP_032095057	MULTISPECIES: DNA topoisomerase III [Alteromonas].	30.95	630	377	16	1	581	1	621	2e-80	280
rs:WP_044655159	DNA topoisomerase III [Bacteroides acidifaciens].	31.36	625	382	14	1	588	1	615	2e-80	282
rs:WP_031861717	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	2e-80	281
rs:WP_047033420	DNA topoisomerase III [Elizabethkingia meningoseptica].	30.62	712	444	18	1	678	1	696	2e-80	281
rs:WP_001549680	DNA topoisomerase 3 [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	2e-80	281
rs:WP_041505349	DNA topoisomerase I [Sanguibacteroides justesenii].	28.65	698	457	16	1	677	1	678	2e-80	281
rs:WP_023931617	DNA topoisomerase III [Photobacterium leiognathi].	32.26	623	366	22	1	581	1	609	2e-80	280
rs:WP_043850762	DNA topoisomerase III [Aeromonas sp. L_1B5_3].	30.27	664	397	20	1	624	1	638	2e-80	280
rs:WP_009537698	DNA topoisomerase [Oribacterium asaccharolyticum].	33.61	598	356	14	1	587	1	568	2e-80	278
rs:WP_011622216	DNA topoisomerase III [Shewanella sp. MR-4].	31.96	629	373	15	1	581	1	622	2e-80	281
rs:WP_016479364	DNA topoisomerase III [Capnocytophaga sp. oral taxon 336].	31.05	715	423	25	1	675	1	685	2e-80	281
rs:WP_042025194	DNA topoisomerase III [Aeromonas enteropelogenes].	29.42	656	413	14	1	624	1	638	2e-80	280
rs:WP_031901756	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	2e-80	281
rs:WP_028069430	DNA topoisomerase I [Sphingobacterium thalpophilum].	32.76	702	415	25	1	673	1	674	2e-80	281
rs:WP_031866479	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	2e-80	281
rs:WP_010249847	DNA topoisomerase [Myroides injenensis].	32.52	701	416	21	1	673	1	672	2e-80	281
rs:WP_031785230	DNA topoisomerase 3 [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	2e-80	281
rs:WP_016147259	DNA topoisomerase III [Butyricicoccus pullicaecorum].	29.87	703	438	21	1	671	1	680	2e-80	281
rs:WP_016219894	DNA topoisomerase III [Dorea sp. 5-2].	30.24	721	438	22	1	687	1	690	2e-80	281
rs:WP_000779859	MULTISPECIES: DNA topoisomerase III [Streptococcus].	34.28	601	348	16	1	587	1	568	2e-80	278
rs:WP_043143773	DNA topoisomerase III [Serratia marcescens].	28.83	673	434	14	1	641	1	660	2e-80	281
rs:WP_046720776	DNA topoisomerase III [Bacillus coagulans].	29.56	724	452	19	3	683	5	713	2e-80	281
rs:WP_021980997	DNA topoisomerase III [Paraprevotella clara CAG:116].	29.37	715	407	18	1	630	1	702	2e-80	281
rs:WP_045178387	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	2e-80	281
rs:WP_002586545	DNA topoisomerase III [[Clostridium] clostridioforme].	29.73	703	439	21	1	671	1	680	2e-80	281
rs:WP_022296137	DNA topoisomerase III [Firmicutes bacterium CAG:272].	29.57	656	418	16	1	638	1	630	2e-80	281
rs:WP_027724303	DNA topoisomerase III [Tuberibacillus calidus].	30.50	659	406	19	3	646	4	625	2e-80	281
rs:WP_029302276	DNA topoisomerase III [Aeromonas hydrophila].	30.06	652	413	16	1	624	1	637	2e-80	280
rs:WP_032586196	DNA topoisomerase I [Bacteroides fragilis].	30.80	711	434	23	1	684	1	680	2e-80	281
rs:WP_031911198	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	2e-80	281
rs:WP_032535951	DNA topoisomerase I [Bacteroides fragilis].	28.16	696	463	14	1	677	1	678	3e-80	281
rs:WP_031789086	DNA topoisomerase III [Staphylococcus aureus].	32.70	636	374	18	3	615	4	608	3e-80	281
rs:WP_005827194	DNA topoisomerase III [Bacteroides uniformis].	30.95	656	395	15	1	609	1	645	3e-80	281
rs:WP_029333124	DNA topoisomerase III [Exiguobacterium oxidotolerans].	29.74	723	441	23	1	681	1	698	3e-80	281
rs:WP_021346323	DNA topoisomerase III [Elizabethkingia meningoseptica].	30.62	712	444	18	1	678	1	696	3e-80	281
rs:WP_009092056	DNA topoisomerase III [Elizabethkingia anophelis].	30.62	712	444	18	1	678	1	696	3e-80	281
tr:E0NQU0_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFM02460.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFM02460.1};	30.80	711	434	23	1	684	20	699	3e-80	281
rs:WP_019131012	DNA topoisomerase I [Bacteroidales bacterium ph8].	30.80	711	434	23	1	684	1	680	3e-80	281
rs:WP_033567093	DNA topoisomerase III [Salmonella enterica].	30.16	640	402	17	1	610	1	625	3e-80	280
rs:WP_006266598	DNA topoisomerase [Myroides odoratimimus].	32.05	699	422	19	1	673	1	672	3e-80	281
rs:WP_038700296	DNA topoisomerase I [Sphingobacterium sp. ML3W].	31.54	707	426	24	1	677	1	679	3e-80	281
rs:WP_038255203	DNA topoisomerase III [Xenorhabdus bovienii].	30.42	641	404	16	1	614	1	626	3e-80	280
rs:WP_016083876	DNA topoisomerase III [Bacillus cereus].	30.25	734	434	24	3	680	4	715	3e-80	281
tr:A0A0D0S1Q1_9BACI	SubName: Full=Anoxybacillus thermarum strain AF/04 contig000014, whole genome shotgun sequence {ECO:0000313|EMBL:KIQ94851.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIQ94851.1};	32.78	598	360	16	3	572	1	584	3e-80	278
rs:WP_014709363	DNA topoisomerase I [Prevotella intermedia].	30.88	719	440	23	1	684	1	697	3e-80	281
rs:WP_017409798	DNA topoisomerase III [Aeromonas hydrophila].	30.06	652	412	16	1	624	1	636	3e-80	280
rs:WP_023914047	DNA topoisomerase 3 [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	3e-80	281
rs:WP_031796011	DNA topoisomerase 3 [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	3e-80	281
rs:WP_011879513	DNA topoisomerase III [Desulfotomaculum reducens].	32.88	657	386	20	3	627	5	638	3e-80	281
rs:WP_036171005	DNA topoisomerase III [Lysinibacillus massiliensis].	32.12	660	387	23	3	627	5	638	3e-80	281
rs:WP_004331500	DNA topoisomerase I [Porphyromonas asaccharolytica].	31.52	698	420	23	4	673	5	672	3e-80	281
rs:WP_019414696	DNA topoisomerase III [Paenisporosarcina sp. TG20].	31.48	648	403	17	3	627	5	634	3e-80	281
rs:WP_024032345	DNA topoisomerase III [Pseudoalteromonas sp. NW 4327].	31.43	614	377	15	1	580	1	604	3e-80	280
rs:WP_034940995	DNA topoisomerase III [Erwinia mallotivora].	32.05	621	363	21	1	581	1	602	3e-80	279
rs:WP_017222480	DNA topoisomerase III [Moritella dasanensis].	31.72	618	377	17	1	582	1	609	3e-80	280
rs:WP_005924167	DNA topoisomerase III [Bacteroides salyersiae].	28.02	696	464	14	1	677	1	678	3e-80	281
rs:WP_014098418	DNA topoisomerase III [Bacillus coagulans].	29.56	724	452	20	3	683	5	713	3e-80	281
rs:WP_039164205	DNA topoisomerase III [Gallibacterium anatis].	30.94	627	372	16	1	581	1	612	3e-80	280
rs:WP_035477107	DNA topoisomerase III [Aliagarivorans taiwanensis].	31.91	611	368	14	1	571	1	603	3e-80	280
rs:WP_024983039	DNA topoisomerase III [Brevibacillus borstelensis].	33.03	657	386	22	3	627	5	639	3e-80	281
rs:WP_039250550	DNA topoisomerase III [Clostridium novyi].	32.48	662	381	21	3	627	5	637	3e-80	281
rs:WP_011590864	DNA topoisomerase III [Clostridium perfringens].	32.93	656	387	21	2	627	6	638	3e-80	281
tr:A0A0A8VKA8_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.53	664	362	24	3	631	5	617	3e-80	281
rs:WP_033014155	DNA topoisomerase III [Geobacillus stearothermophilus].	30.20	659	407	17	3	646	4	624	3e-80	281
rs:WP_043125882	DNA topoisomerase III [Aeromonas hydrophila].	29.91	652	414	16	1	624	1	637	3e-80	280
rs:WP_046816037	DNA topoisomerase III [Pseudomonas putida].	28.20	656	430	14	1	629	1	642	3e-80	280
rs:WP_012720525	DNA topoisomerase III [Clostridium botulinum].	31.69	669	405	23	3	638	5	654	3e-80	281
rs:WP_037612753	DNA topoisomerase [Streptococcus sp. OBRC6].	34.06	593	346	16	1	580	1	561	3e-80	277
rs:WP_031943142	DNA processing protein [uncultured bacterium].	30.26	651	409	15	1	614	1	643	3e-80	280
rs:WP_004932196	MULTISPECIES: DNA topoisomerase III [Serratia].	31.10	611	382	17	1	581	1	602	3e-80	279
tr:I7IL22_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.71	741	399	28	3	680	5	701	3e-80	283
tr:A0A0D8IXC4_9FIRM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KJF39154.1};	28.94	705	446	19	1	676	1	679	3e-80	281
rs:WP_045788841	DNA topoisomerase III [Aeromonas hydrophila].	30.06	652	413	16	1	624	1	637	3e-80	280
rs:WP_041966979	DNA topoisomerase III [Bacillus selenatarsenatis].	29.28	724	456	20	1	681	1	711	3e-80	281
rs:WP_010801747	MULTISPECIES: DNA topoisomerase III [Bacteroidales].	30.73	703	430	22	1	676	1	673	3e-80	281
rs:WP_031890145	DNA topoisomerase 3 [Staphylococcus aureus].	32.70	636	374	18	3	615	4	608	3e-80	281
rs:WP_006906929	DNA topoisomerase III [Shuttleworthia satelles].	33.90	593	347	16	1	580	1	561	3e-80	277
rs:WP_006798321	DNA topoisomerase I [Dysgonomonas gadei].	31.29	703	441	21	1	680	1	684	3e-80	281
rs:WP_038605690	DNA topoisomerase III [Bacteroides dorei].	29.01	717	411	18	1	629	1	707	3e-80	281
rs:WP_003029074	MULTISPECIES: DNA topoisomerase III [Streptococcus].	33.17	597	356	13	1	585	1	566	3e-80	277
rs:WP_046151725	DNA topoisomerase I [Parabacteroides sp. HGS0025].	31.30	706	437	22	1	680	1	684	3e-80	281
rs:WP_021183047	DNA topoisomerase III [Pantoea sp. AS-PWVM4].	31.86	612	362	20	1	574	1	595	3e-80	279
rs:WP_000838504	DNA topoisomerase III [Staphylococcus aureus].	32.71	642	366	18	3	615	4	608	3e-80	281
rs:WP_041516059	DNA topoisomerase I [Flavobacterium hibernum].	31.82	704	429	22	1	678	1	679	3e-80	280
rs:WP_027409811	DNA topoisomerase III [Anoxybacillus tepidamans].	29.74	723	452	19	1	681	1	709	4e-80	281
rs:WP_022525413	hypothetical protein [Streptococcus anginosus].	33.50	600	354	16	1	587	1	568	4e-80	277
rs:WP_011586942	DNA topoisomerase III [Cytophaga hutchinsonii].	29.82	711	435	17	1	662	1	696	4e-80	281
rs:WP_046950329	DNA topoisomerase III [Haemophilus haemolyticus].	32.37	624	370	19	1	583	1	613	4e-80	280
tr:Q12LJ6_SHEDO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.10	643	396	17	1	603	1	636	4e-80	280
rs:WP_032459396	DNA topoisomerase III [Streptococcus agalactiae].	34.51	594	338	16	3	580	5	563	4e-80	277
rs:WP_047130864	DNA topoisomerase III [Staphylococcus condimenti].	32.70	633	377	16	3	615	4	607	4e-80	281
rs:WP_042356994	DNA topoisomerase III [Bacillus sp. MT2].	33.28	658	382	21	3	627	5	638	4e-80	281
rs:WP_019452756	DNA topoisomerase III [Serratia marcescens].	31.10	611	382	17	1	581	1	602	4e-80	279
rs:WP_034543388	DNA topoisomerase III, partial [Bacteroides pyogenes].	31.13	652	369	18	1	588	1	636	4e-80	280
rs:WP_000838484	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	4e-80	281
rs:WP_044190226	DNA topoisomerase I [Porphyromonas sp. COT-290 OH860].	30.58	726	433	24	1	684	1	697	4e-80	281
rs:WP_007754171	MULTISPECIES: DNA topoisomerase I [Bacteroides].	28.02	696	464	14	1	677	1	678	4e-80	280
rs:WP_006646506	DNA topoisomerase III [Photobacterium sp. SKA34].	31.94	623	368	22	1	581	1	609	4e-80	279
rs:WP_031870002	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	4e-80	281
rs:WP_004293865	DNA topoisomerase I [Bacteroides eggerthii].	30.25	714	434	24	1	684	1	680	4e-80	280
rs:WP_044801014	DNA topoisomerase III [Aeromonas hydrophila].	30.06	652	413	16	1	624	1	637	4e-80	280
rs:WP_000838491	DNA topoisomerase 3 [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	4e-80	281
rs:WP_000838496	DNA topoisomerase III [Staphylococcus aureus].	32.70	636	374	18	3	615	4	608	4e-80	281
rs:WP_004364080	DNA topoisomerase III [Prevotella nigrescens].	30.73	716	445	22	1	684	1	697	4e-80	281
rs:WP_018365297	DNA topoisomerase [Streptococcus caballi].	33.83	600	352	15	1	587	1	568	4e-80	277
gpu:CP011832_1584	DNA topoisomerase 3 [Geobacillus sp. 12AMOR1]	30.20	659	407	17	3	646	4	624	4e-80	280
rs:WP_033910510	DNA topoisomerase III [Neisseria gonorrhoeae].	31.41	659	389	20	1	610	1	645	4e-80	280
rs:WP_035188903	DNA topoisomerase III [Bacillus coagulans].	29.56	724	452	20	3	683	5	713	4e-80	281
rs:WP_003756869	DNA topoisomerase III [Listeria grayi].	32.20	649	396	20	2	631	4	627	4e-80	281
rs:WP_017032445	DNA topoisomerase III [Vibrio breoganii].	31.80	607	365	17	2	571	3	597	4e-80	279
rs:WP_031901836	DNA topoisomerase 3 [Staphylococcus aureus].	32.70	636	374	18	3	615	4	608	4e-80	281
rs:WP_045181198	DNA topoisomerase III [Elizabethkingia sp. BM10].	30.62	712	444	18	1	678	1	696	4e-80	280
rs:WP_021179591	DNA topoisomerase III [Serratia fonticola].	30.15	607	391	13	1	581	1	600	4e-80	280
rs:WP_040882743	DNA topoisomerase III [Johnsonella ignava].	30.04	709	438	20	3	683	1	679	4e-80	280
rs:WP_013724181	DNA topoisomerase III [Aeromonas veronii].	30.52	652	411	14	1	624	1	638	4e-80	279
rs:WP_028087322	DNA topoisomerase III [Dorea longicatena].	31.40	691	387	19	3	627	4	673	4e-80	282
rs:WP_013666865	DNA topoisomerase [Sphingobacterium sp. 21].	31.78	708	428	24	1	680	1	681	4e-80	280
rs:WP_034579773	DNA topoisomerase [Kallipyga massiliensis].	34.28	601	344	16	3	587	5	570	4e-80	277
rs:WP_004822267	DNA topoisomerase III [Peptoniphilus indolicus].	33.07	632	356	18	3	615	5	588	4e-80	280
rs:WP_034866021	DNA topoisomerase III [Elizabethkingia miricola].	30.62	712	444	18	1	678	1	696	4e-80	280
rs:WP_032532598	DNA topoisomerase I [Bacteroides fragilis].	29.10	701	449	19	1	677	1	677	4e-80	280
rs:WP_006427725	DNA topoisomerase III [Dorea longicatena].	31.20	689	391	19	3	627	4	673	4e-80	282
rs:WP_005423585	DNA topoisomerase III [[Ruminococcus] obeum].	30.20	702	446	16	1	679	1	681	4e-80	280
tr:C0C5H6_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.43	663	387	23	3	627	16	655	4e-80	281
rs:WP_002494670	DNA topoisomerase III [Staphylococcus epidermidis].	33.65	633	372	20	3	615	4	608	4e-80	281
rs:WP_029140971	DNA topoisomerase III [Streptococcus agalactiae].	33.56	599	355	15	1	587	1	568	4e-80	277
rs:WP_046942476	DNA topoisomerase III [Haemophilus haemolyticus].	31.57	624	375	17	1	583	1	613	4e-80	279
rs:WP_031942852	DNA topoisomerase III [uncultured bacterium].	30.26	651	409	15	1	614	1	643	4e-80	280
rs:WP_040978776	DNA topoisomerase III [Oceanobacillus sp. S5].	31.94	648	397	21	3	626	5	632	4e-80	281
rs:WP_046497084	DNA topoisomerase III [Citrobacter amalonaticus].	29.86	643	412	14	1	618	1	629	4e-80	280
rs:WP_000838500	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	4e-80	281
rs:WP_008422242	DNA topoisomerase III [Clostridium sp. Maddingley MBC34-26].	30.63	653	403	20	3	627	5	635	4e-80	281
rs:WP_016662202	DNA topoisomerase III [Bacteroides stercoris].	28.12	697	462	15	1	677	1	678	5e-80	280
rs:WP_005800963	DNA topoisomerase I [Bacteroides fragilis].	28.80	698	456	16	1	677	1	678	5e-80	280
rs:WP_015378097	DNA topoisomerase III [Serratia marcescens].	31.10	611	382	17	1	581	1	602	5e-80	279
rs:WP_038182493	DNA topoisomerase III [Xenorhabdus bovienii].	30.37	642	398	16	1	614	1	621	5e-80	280
rs:WP_000838478	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	5e-80	281
rs:WP_037441084	DNA topoisomerase I [Sphingobacterium antarcticum].	31.82	704	429	22	1	678	1	679	5e-80	280
rs:WP_043040358	DNA topoisomerase III [Staphylococcus aureus].	32.70	636	374	18	3	615	4	608	5e-80	281
rs:WP_008667766	MULTISPECIES: DNA topoisomerase III [Bacteroides].	29.01	717	413	18	1	630	1	708	5e-80	281
rs:WP_000838482	DNA topoisomerase 3 [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	5e-80	280
tr:J9GKB8_9ZZZZ	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EJX00095.1};	30.14	710	395	21	1	624	1	695	5e-80	280
rs:WP_001235784	DNA topoisomerase III [Escherichia coli].	30.82	610	385	16	1	581	1	602	5e-80	279
tr:A9N2T9_SALPB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.86	643	412	14	1	618	1	629	5e-80	280
rs:WP_009347193	DNA topoisomerase I [Alloprevotella rava].	30.44	726	434	24	1	684	1	697	5e-80	280
rs:WP_000115176	DNA topoisomerase III [Bacillus cereus].	29.43	717	452	18	3	680	4	705	5e-80	281
rs:WP_017550814	DNA topoisomerase III [Bacillus coagulans].	29.90	729	443	21	3	683	5	713	5e-80	281
rs:WP_046288283	DNA topoisomerase III [Pantoea sp. 3.5.1].	30.84	629	360	19	1	581	1	602	5e-80	279
rs:WP_045292289	DNA topoisomerase III [Enterobacter sp. 42324].	30.77	611	388	13	1	587	1	600	5e-80	278
rs:WP_044907652	DNA topoisomerase III [[Clostridium] innocuum].	29.08	705	445	19	1	676	1	679	5e-80	280
rs:WP_016352275	DNA topoisomerase III [Aeromonas hydrophila].	29.91	652	414	16	1	624	1	637	5e-80	279
tr:B6W693_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.11	598	366	16	1	590	5	576	5e-80	277
rs:WP_008674864	DNA topoisomerase III [Bacteroides sp. 9_1_42FAA].	29.01	717	411	18	1	629	1	707	5e-80	280
rs:WP_032941057	DNA topoisomerase III [Bacteroides sp. 3_1_33FAA].	29.01	717	411	18	1	629	1	707	5e-80	280
rs:WP_013597426	DNA topoisomerase III [Weeksella virosa].	31.68	704	439	21	1	678	1	688	5e-80	280
rs:WP_039913594	DNA topoisomerase [Anaerococcus hydrogenalis].	33.11	598	366	16	1	590	1	572	5e-80	277
rs:WP_047212299	DNA topoisomerase [Streptococcus agalactiae].	34.28	601	344	16	3	587	5	570	5e-80	277
rs:WP_039165985	DNA topoisomerase III [Gallibacterium anatis].	31.05	628	370	17	1	581	1	612	5e-80	279
rs:WP_039174200	DNA topoisomerase III [Gallibacterium genomosp. 1].	30.94	627	372	16	1	581	1	612	5e-80	279
rs:WP_015701651	DNA topoisomerase III [Haemophilus influenzae].	31.57	624	375	18	1	583	1	613	5e-80	279
rs:WP_038161991	DNA topoisomerase III [Trabulsiella guamensis].	29.86	643	412	14	1	618	1	629	5e-80	280
rs:WP_019555143	hypothetical protein [Propionispira raffinosivorans].	31.94	648	401	19	4	627	6	637	5e-80	281
rs:WP_032676550	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	29.86	643	412	14	1	618	1	629	5e-80	280
rs:WP_019243290	DNA topoisomerase III [Bacillus massilioanorexius].	32.57	657	388	22	3	627	5	638	5e-80	281
rs:WP_044737023	DNA topoisomerase III [Geobacillus kaustophilus].	29.01	717	466	20	1	681	1	710	5e-80	281
rs:WP_007840712	MULTISPECIES: DNA topoisomerase III [Bacteroides].	29.01	717	411	18	1	629	1	707	5e-80	280
rs:WP_023490164	DNA topoisomerase 3 [Serratia sp. DD3].	30.88	612	382	17	1	581	1	602	5e-80	279
rs:WP_031882918	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	5e-80	280
rs:WP_013745451	DNA topoisomerase III [Gallibacterium anatis].	30.94	627	372	16	1	581	1	612	5e-80	279
rs:WP_039310023	DNA topoisomerase III [Clostridium botulinum].	32.13	638	386	19	3	615	5	620	5e-80	281
rs:WP_043588193	DNA topoisomerase [Diplosphaera colitermitum].	30.34	679	396	17	1	624	1	657	5e-80	283
tr:A0A0C7I9V3_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.53	664	362	24	3	631	5	617	5e-80	280
tr:M8T8N0_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.73	641	399	19	3	608	1	631	5e-80	279
rs:WP_006829182	DNA topoisomerase III [Planococcus antarcticus].	33.69	656	374	24	3	627	4	629	5e-80	281
rs:WP_039090578	DNA topoisomerase III [Gallibacterium anatis].	31.05	628	370	17	1	581	1	612	6e-80	279
rs:WP_013489388	DNA topoisomerase III [Bacillus cellulosilyticus].	32.26	651	400	18	3	627	5	640	6e-80	281
rs:WP_025020293	DNA topoisomerase III [Lactobacillus equi].	31.52	625	374	14	2	614	4	586	6e-80	280
rs:WP_011231183	DNA topoisomerase III [Geobacillus kaustophilus].	30.20	659	407	17	3	646	4	624	6e-80	280
rs:WP_044332759	DNA topoisomerase III [Haemophilus influenzae].	31.73	624	374	18	1	583	1	613	6e-80	279
rs:WP_047211640	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	6e-80	280
rs:WP_002587416	DNA topoisomerase III [[Clostridium] clostridioforme].	28.76	699	444	18	2	671	4	677	6e-80	280
rs:WP_007201633	DNA topoisomerase III [Fictibacillus macauensis].	30.76	660	403	17	3	646	4	625	6e-80	280
rs:WP_026706431	DNA topoisomerase I [Flavobacterium soli].	31.73	706	431	22	1	680	1	681	6e-80	280
rs:WP_007856244	DNA topoisomerase III [Bacteroides dorei].	29.01	717	411	18	1	629	1	707	6e-80	280
rs:WP_003012643	DNA topoisomerase [Sphingobacterium spiritivorum].	31.41	710	429	23	1	680	1	682	6e-80	280
rs:WP_023627631	hypothetical protein [Bacillus sp. 17376].	29.14	724	456	18	1	681	1	710	6e-80	281
rs:WP_028974183	hypothetical protein [Spirochaeta cellobiosiphila].	31.86	634	388	15	3	615	4	614	6e-80	280
rs:WP_021676799	DNA topoisomerase [Porphyromonas gingivalis].	29.75	726	439	23	1	684	1	697	6e-80	280
rs:WP_007391818	MULTISPECIES: DNA topoisomerase [Firmicutes].	34.28	601	344	16	3	587	5	570	6e-80	277
rs:WP_021817730	hypothetical protein [Halomonas sp. BJGMM-B45].	29.21	647	408	15	2	614	3	633	6e-80	280
rs:WP_004070731	DNA topoisomerase III [Clostridium sp. ASF502].	29.86	700	435	20	1	670	1	674	6e-80	280
rs:WP_013509359	DNA topoisomerase III [Pantoea sp. At-9b].	31.86	612	362	20	1	574	1	595	6e-80	278
rs:WP_009247719	MULTISPECIES: DNA topoisomerase III [Lachnospiraceae].	32.57	657	385	23	3	627	4	634	6e-80	281
rs:WP_011860791	DNA topoisomerase [Peptoclostridium difficile].	34.28	598	352	14	1	587	1	568	6e-80	276
rs:WP_031865861	DNA topoisomerase III [Staphylococcus aureus].	32.70	636	374	18	3	615	4	608	6e-80	280
rs:WP_043160134	DNA topoisomerase III [Aeromonas hydrophila].	30.46	627	400	15	1	599	1	619	6e-80	279
rs:WP_021130050	DNA topoisomerase III family protein [[Clostridium] sordellii].	32.53	664	362	24	3	631	5	617	6e-80	280
rs:WP_025831777	DNA topoisomerase III [Bacteroides stercorirosoris].	31.28	633	380	15	1	588	1	623	6e-80	281
rs:WP_009298985	MULTISPECIES: DNA topoisomerase III [Clostridiales].	29.71	700	437	20	1	671	1	674	6e-80	280
tr:J9H4U6_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJX11118.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EJX11118.1};	29.09	739	398	20	1	630	49	770	6e-80	281
rs:WP_036930050	DNA topoisomerase I [Prevotella timonensis].	30.52	711	437	22	1	684	1	681	6e-80	280
rs:WP_038263715	DNA topoisomerase III [Xenorhabdus cabanillasii].	29.89	659	419	16	1	630	1	645	6e-80	279
rs:WP_018753683	DNA topoisomerase III [Paenibacillus sanguinis].	30.30	670	401	18	3	646	4	633	6e-80	280
rs:WP_007084794	DNA topoisomerase III [Bacillus bataviensis].	29.88	733	442	20	1	682	1	712	7e-80	280
tr:D4LVC5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.79	715	444	21	3	687	5	691	7e-80	280
rs:WP_043810271	DNA topoisomerase [Rubrivivax gelatinosus].	29.36	722	445	20	3	680	5	705	7e-80	283
rs:WP_007845849	DNA topoisomerase III [Bacteroides dorei].	29.01	717	411	18	1	629	1	707	7e-80	280
rs:WP_004362423	DNA topoisomerase III [Prevotella nigrescens].	31.02	719	439	25	1	684	1	697	7e-80	280
rs:WP_021430807	DNA topoisomerase III family protein [[Clostridium] bifermentans].	32.17	659	371	23	3	631	5	617	7e-80	280
rs:WP_038182308	DNA topoisomerase III [Viridibacillus arenosi].	29.45	703	459	16	1	673	3	698	7e-80	280
rs:WP_044175018	DNA topoisomerase III [Photobacterium damselae].	31.84	625	370	22	1	583	1	611	7e-80	278
rs:WP_037606927	DNA topoisomerase [Streptococcus sp. CM7].	34.45	598	349	15	2	587	4	570	7e-80	276
rs:WP_013407034	DNA topoisomerase [Leadbetterella byssophila].	31.44	706	427	22	1	677	1	678	7e-80	280
rs:WP_017053489	DNA topoisomerase III [Vibrio genomosp. F6].	30.85	632	395	13	2	599	3	626	7e-80	278
tr:A0A0C7J747_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.53	664	362	24	3	631	5	617	7e-80	280
rs:WP_033827051	DNA topoisomerase III [Bacillus sp. KW-12].	30.82	662	400	19	3	646	4	625	7e-80	280
rs:WP_013526469	DNA topoisomerase III [Haemophilus influenzae].	32.21	624	371	19	1	583	1	613	7e-80	279
rs:WP_040198136	DNA topoisomerase III [Candidatus Soleaferrea massiliensis].	30.29	647	406	18	3	627	5	628	7e-80	280
rs:WP_032191370	DNA topoisomerase III [Escherichia coli].	30.02	643	399	18	1	610	1	625	7e-80	279
rs:WP_000838483	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	7e-80	280
rs:WP_026573203	DNA topoisomerase III [Bacillus sp. UNC438CL73TsuS30].	30.72	726	444	23	1	682	1	711	7e-80	280
rs:WP_024792519	DNA topoisomerase III [Salmonella enterica].	29.86	643	412	14	1	618	1	629	7e-80	279
rs:WP_039245269	DNA topoisomerase III [Clostridium novyi].	32.47	656	389	19	3	627	5	637	7e-80	280
rs:WP_032941992	DNA topoisomerase III [Bacteroides massiliensis].	29.71	727	393	21	1	629	1	707	7e-80	280
rs:WP_000838480	DNA topoisomerase III [Staphylococcus aureus].	32.70	636	374	18	3	615	4	608	7e-80	280
rs:WP_040034471	DNA topoisomerase III [Haemophilus influenzae].	31.57	624	375	18	1	583	1	613	7e-80	278
rs:WP_041216786	DNA topoisomerase III [Aeromonas hydrophila].	30.46	627	400	15	1	599	1	619	7e-80	279
rs:WP_000838501	DNA topoisomerase III [Staphylococcus aureus].	32.86	636	373	18	3	615	4	608	8e-80	280
rs:WP_007365528	DNA topoisomerase I [Porphyromonas uenonis].	31.16	706	412	23	4	673	5	672	8e-80	280
rs:WP_018158381	hypothetical protein, partial [Thioalkalivibrio sp. ALE14].	28.25	701	425	16	41	670	3	696	8e-80	280
rs:WP_037372006	DNA topoisomerase, partial [Selenomonas sp. AE3005].	28.12	672	436	14	1	640	1	657	8e-80	279
tr:A0A078QAC8_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:KDS20329.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KDS20329.1};	29.45	696	447	19	4	677	5	678	8e-80	280
rs:WP_028896492	DNA topoisomerase I [Prevotella sp. HUN102].	30.32	696	436	19	1	673	2	671	8e-80	280
rs:WP_033114850	DNA topoisomerase III [Aeromonas sp. AE122].	29.78	648	413	13	1	620	1	634	8e-80	279
rs:WP_035185002	DNA topoisomerase III [Bacillus coagulans].	29.56	724	452	20	3	683	5	713	8e-80	280
rs:WP_046417497	DNA topoisomerase [Xylella fastidiosa].	30.71	674	415	18	1	630	1	666	8e-80	279
rs:WP_007895166	DNA topoisomerase III [Streptococcus pseudoporcinus].	34.12	595	339	16	3	580	5	563	8e-80	276
rs:WP_006248877	DNA topoisomerase III [Mannheimia haemolytica].	28.97	642	414	13	1	614	1	628	8e-80	279
rs:WP_001235879	DNA topoisomerase III, partial [Salmonella enterica].	31.58	627	372	20	1	581	1	616	8e-80	278
rs:WP_005709182	DNA topoisomerase III [Haemophilus paraphrohaemolyticus].	32.09	617	375	16	1	584	1	606	8e-80	278
rs:WP_024997486	DNA topoisomerase III [Bacteroides graminisolvens].	30.87	703	391	21	1	625	1	686	8e-80	280
rs:WP_011961680	DNA topoisomerase III [Haemophilus influenzae].	32.00	625	371	19	1	583	1	613	8e-80	278
tr:D1K925_9BACE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEZ19663.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EEZ19663.1};	29.01	717	411	18	1	629	12	718	8e-80	280
rs:WP_037349427	DNA topoisomerase III [Selenomonas artemidis].	29.82	664	412	17	3	629	4	650	8e-80	280
rs:WP_040230287	DNA topoisomerase III [Citrobacter sp. CIP 55.13].	30.31	607	392	11	1	585	1	598	8e-80	277
rs:WP_031775289	DNA topoisomerase 3 [Staphylococcus aureus].	32.70	636	374	18	3	615	4	608	9e-80	280
rs:WP_004371701	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	30.52	711	437	22	1	684	1	681	9e-80	280
rs:WP_021977241	DNA topoisomerase [Ruminococcus sp. CAG:17].	31.46	658	396	21	3	627	4	639	9e-80	280
rs:WP_000838477	DNA topoisomerase III [Staphylococcus aureus].	32.70	636	374	18	3	615	4	608	9e-80	280
rs:WP_016322370	DNA topoisomerase III [Oscillibacter sp. 1-3].	29.57	700	437	20	1	670	1	674	9e-80	280
rs:WP_016147228	DNA topoisomerase III [Butyricicoccus pullicaecorum].	30.09	698	433	19	1	670	1	671	9e-80	280
rs:WP_004832505	DNA topoisomerase [Parvimonas micra].	34.17	600	350	16	1	587	1	568	9e-80	276
rs:WP_033626145	DNA topoisomerase [Enterococcus faecalis].	33.77	607	329	20	1	580	1	561	9e-80	276
rs:WP_029471610	DNA topoisomerase III [Clostridiales bacterium VE202-06].	30.20	702	446	16	1	679	1	681	9e-80	280
rs:WP_007482644	MULTISPECIES: DNA topoisomerase I [Bacteroides].	28.02	696	464	14	1	677	1	678	9e-80	280
rs:WP_019975895	DNA topoisomerase [Empedobacter brevis].	31.46	712	425	23	1	680	1	681	9e-80	279
rs:WP_029567330	DNA topoisomerase III [Bacillus cibi].	31.40	691	438	18	3	664	5	688	9e-80	280
rs:WP_032588335	MULTISPECIES: DNA topoisomerase I [Bacteroides].	28.02	696	464	14	1	677	1	678	9e-80	279
rs:WP_042610999	DNA topoisomerase III [Haemophilus influenzae].	31.57	624	375	18	1	583	1	613	9e-80	278
rs:WP_016402350	DNA topoisomerase III [Agarivorans albus].	29.92	625	398	12	1	596	1	614	9e-80	278
rs:WP_044270609	DNA topoisomerase I [Candidatus Bacteroides timonensis].	28.45	696	461	14	1	677	1	678	9e-80	279
rs:WP_038354068	DNA topoisomerase III [Eubacterium limosum].	32.07	633	391	15	3	615	7	620	9e-80	280
rs:WP_046835674	DNA topoisomerase III [Staphylococcus succinus].	32.06	627	391	14	3	615	4	609	1e-79	280
rs:WP_035116511	DNA topoisomerase III [Clostridium sp. NCR].	32.17	659	371	23	3	631	5	617	1e-79	280
rs:WP_025018050	DNA topoisomerase III [Bacteroides sartorii].	29.71	727	393	21	1	629	1	707	1e-79	280
gpu:CP011068_1036	DNA topoisomerase [Streptococcus pyogenes]	34.22	602	343	17	3	587	5	570	1e-79	276
rs:WP_006122511	MULTISPECIES: DNA topoisomerase [Proteobacteria].	30.26	651	409	15	1	614	1	643	1e-79	279
rs:WP_005334803	DNA topoisomerase III [Dorea formicigenerans].	30.51	708	436	19	1	679	1	681	1e-79	280
rs:WP_046098044	DNA topoisomerase III [Avibacterium paragallinarum].	32.03	640	386	19	1	605	1	626	1e-79	278
rs:WP_019568985	hypothetical protein, partial [Thioalkalivibrio sp. ALMg13-2].	28.39	701	424	17	41	670	3	696	1e-79	280
rs:WP_031942736	DNA topoisomerase III [uncultured bacterium].	30.26	651	409	15	1	614	1	643	1e-79	279
rs:WP_020998778	DNA topoisomerase [Streptococcus intermedius].	33.22	602	353	14	1	587	1	568	1e-79	276
rs:WP_004320647	DNA topoisomerase I [Bacteroides ovatus].	30.67	714	432	24	1	684	1	681	1e-79	279
rs:WP_021875939	DNA topoisomerase [Clostridium chauvoei].	32.62	656	386	26	3	627	5	635	1e-79	280
rs:WP_026564446	DNA topoisomerase III [Bacillus sp. UNC41MFS5].	30.40	658	408	15	3	646	4	625	1e-79	279
rs:WP_018168697	hypothetical protein, partial [Thioalkalivibrio sp. ALMg9].	28.39	701	424	17	41	670	3	696	1e-79	280
rs:WP_025070722	DNA topoisomerase I [Prevotella oulorum].	30.34	725	436	23	1	684	1	697	1e-79	280
rs:WP_020909946	DNA topoisomerase III [Haemophilus influenzae].	31.46	623	377	17	1	583	1	613	1e-79	278
rs:WP_002107335	DNA topoisomerase III [Bacillus cereus].	29.65	715	453	17	3	680	5	706	1e-79	280
rs:WP_034865743	DNA topoisomerase III [Enterococcus durans].	31.30	623	372	16	2	611	3	582	1e-79	279
rs:WP_029283791	DNA topoisomerase III [Bacillus indicus].	31.40	691	438	18	3	664	5	688	1e-79	280
rs:WP_039386234	DNA topoisomerase III [Pantoea agglomerans].	31.10	627	361	18	1	581	1	602	1e-79	278
rs:WP_031905536	DNA topoisomerase 3 [Staphylococcus aureus].	32.70	636	374	18	3	615	4	608	1e-79	280
rs:WP_026971115	DNA topoisomerase III [Aliagarivorans marinus].	32.18	606	368	13	1	571	1	598	1e-79	278
tr:D7IPC2_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFI09260.1};	29.71	680	405	18	28	647	13	679	1e-79	279
rs:WP_007649355	DNA topoisomerase III [Shewanella sp. HN-41].	31.10	643	382	15	1	591	1	634	1e-79	280
rs:WP_005662588	DNA topoisomerase III [Haemophilus influenzae].	32.05	624	372	19	1	583	1	613	1e-79	278
rs:WP_009130680	DNA topoisomerase III [Bacteroides oleiciplenus].	30.93	653	392	16	1	604	1	643	1e-79	280
tr:G5GKW0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.95	592	346	16	2	580	19	578	1e-79	276
rs:WP_011114056	MULTISPECIES: DNA topoisomerase [Bacteria].	30.26	651	409	15	1	614	1	643	1e-79	279
rs:WP_002489011	DNA topoisomerase III [Staphylococcus epidermidis].	33.65	633	372	20	3	615	4	608	1e-79	280
tr:A0A0D0RIW4_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.81	643	393	19	3	626	4	626	1e-79	279
rs:WP_032537565	DNA topoisomerase III [Bacteroides fragilis].	31.70	631	372	18	1	588	1	615	1e-79	280
rs:WP_033126088	DNA topoisomerase III [Eubacterium sp. ER2].	30.26	704	443	17	1	679	1	681	1e-79	279
rs:WP_031763953	DNA topoisomerase III [Staphylococcus aureus].	32.70	636	374	18	3	615	4	608	1e-79	280
rs:WP_011707714	DNA topoisomerase III [Aeromonas hydrophila].	30.44	634	404	16	1	604	1	627	1e-79	278
rs:WP_026769694	DNA topoisomerase I [Sediminibacterium sp. OR53].	31.16	706	420	25	1	673	1	673	1e-79	279
rs:WP_044783964	DNA topoisomerase III [Escherichia coli].	29.68	684	415	19	1	641	1	661	1e-79	279
tr:C9AL42_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.97	620	378	14	2	611	3	582	1e-79	279
rs:WP_045173686	DNA topoisomerase III [Staphylococcus aureus].	32.70	636	374	18	3	615	4	608	1e-79	280
rs:WP_025146083	hypothetical protein [Sphingobacterium sp. H1ai].	30.17	706	449	21	1	675	1	693	1e-79	279
rs:WP_006627218	DNA topoisomerase [Bulleidia extructa].	33.83	609	340	18	1	587	1	568	1e-79	276
rs:WP_024566950	DNA topoisomerase III [Elizabethkingia anophelis].	31.19	715	436	21	1	678	1	696	1e-79	279
rs:WP_042601082	DNA topoisomerase III [Haemophilus influenzae].	32.05	624	372	19	1	583	1	613	1e-79	278
rs:WP_002838480	DNA topoisomerase III [Finegoldia magna].	33.00	597	368	15	1	590	1	572	1e-79	276
rs:WP_039238656	MULTISPECIES: DNA topoisomerase III [Clostridium].	32.47	656	389	19	3	627	5	637	1e-79	280
rs:WP_017751809	hypothetical protein [Clostridium tyrobutyricum].	30.77	689	414	23	3	658	5	663	1e-79	280
rs:WP_032532245	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	29.00	700	451	19	1	677	1	677	1e-79	279
sp:TOP3_BACSK	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	31.50	654	397	21	2	627	4	634	1e-79	280
rs:WP_010894513	DNA topoisomerase [Xylella fastidiosa].	30.86	674	414	18	1	630	1	666	1e-79	279
rs:WP_046898907	DNA topoisomerase III [Serratia marcescens].	30.93	611	383	17	1	581	1	602	1e-79	278
rs:WP_007215190	DNA topoisomerase I [Bacteroides cellulosilyticus].	31.72	703	423	24	1	676	1	673	1e-79	279
rs:WP_004341621	DNA topoisomerase I [Prevotella buccae].	30.21	725	437	23	1	684	1	697	1e-79	279
rs:WP_024565255	DNA topoisomerase III [Elizabethkingia anophelis].	30.62	712	444	18	1	678	1	696	1e-79	279
rs:WP_007790064	DNA topoisomerase [Peptostreptococcus stomatis].	33.83	600	352	16	1	587	1	568	1e-79	276
rs:WP_032211070	DNA topoisomerase III [Escherichia coli].	30.33	643	396	17	1	610	1	624	1e-79	278
rs:WP_044742825	DNA topoisomerase III [Anoxybacillus sp. ATCC BAA-2555].	29.11	718	464	21	1	681	1	710	1e-79	280
rs:WP_014550410	DNA topoisomerase III [Haemophilus influenzae].	31.57	624	375	18	1	583	1	613	1e-79	278
rs:WP_003042371	DNA topoisomerase III [Streptococcus anginosus].	33.89	596	343	18	1	580	1	561	1e-79	276
tr:S9BCI7_STRAG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.51	594	338	16	3	580	40	598	1e-79	276
rs:WP_006783117	DNA topoisomerase III [[Clostridium] hathewayi].	30.95	656	405	17	3	627	4	642	1e-79	280
rs:WP_001175889	DNA topoisomerase III [Escherichia coli].	30.17	643	397	16	1	610	1	624	1e-79	278
rs:WP_044947481	DNA topoisomerase III [Blautia schinkii].	32.12	657	394	21	3	627	4	640	1e-79	280
rs:WP_001235885	DNA topoisomerase [Salmonella enterica].	30.26	651	409	15	1	614	1	643	1e-79	279
tr:A0A0A5IJ55_CITKO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.87	609	390	12	1	587	1	600	1e-79	276
rs:WP_028884328	DNA topoisomerase III [Taylorella asinigenitalis].	31.44	741	401	28	3	680	5	701	1e-79	281
rs:WP_011244861	DNA topoisomerase [Bacillus thuringiensis].	29.83	724	430	22	3	675	10	706	1e-79	280
rs:WP_046939870	DNA topoisomerase III [Haemophilus haemolyticus].	32.37	624	370	19	1	583	1	613	1e-79	278
rs:WP_044820516	DNA topoisomerase III [Bacteroides fragilis].	30.57	700	375	22	28	629	13	699	1e-79	279
rs:WP_045108681	DNA topoisomerase III [Moritella viscosa].	31.42	643	394	19	1	606	1	633	1e-79	278
tr:W4PUM3_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE22789.1};	31.55	653	365	20	1	588	16	651	2e-79	280
rs:WP_034674086	DNA topoisomerase III, partial [Bacillus niacini].	29.96	711	435	23	1	664	1	695	2e-79	279
rs:WP_022275766	DNA topoisomerase III [Bacteroides finegoldii CAG:203].	29.75	706	410	18	1	629	1	697	2e-79	279
tr:A0A016FRT4_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EYA20988.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EYA20988.1};	29.08	698	447	19	4	677	5	678	2e-79	279
rs:WP_034440480	DNA topoisomerase III [Candidatus Clostridium anorexicamassiliense].	31.13	652	401	21	3	627	5	635	2e-79	280
rs:WP_038484294	DNA topoisomerase III [Bacillus lehensis].	32.52	655	387	24	2	627	4	632	2e-79	280
rs:WP_033648773	DNA topoisomerase III [Serratia marcescens].	29.32	607	397	10	1	581	1	601	2e-79	278
rs:WP_011108131	DNA topoisomerase III [Bacteroides thetaiotaomicron].	31.36	625	381	15	1	588	1	614	2e-79	279
rs:WP_009835356	DNA topoisomerase III [Marinomonas sp. MED121].	32.79	616	368	18	1	581	1	605	2e-79	278
rs:WP_008616570	DNA topoisomerase I [Paraprevotella clara].	30.16	703	441	22	1	676	1	680	2e-79	279
rs:WP_000114568	DNA topoisomerase III [Bacillus thuringiensis].	29.83	724	430	22	3	675	4	700	2e-79	279
rs:WP_017895874	hypothetical protein [Clostridium tyrobutyricum].	30.77	689	414	23	3	658	5	663	2e-79	280
tr:W1U0R1_STRAP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.28	601	344	16	3	587	40	605	2e-79	276
rs:WP_011202386	DNA topoisomerase I [Bacteroides fragilis].	27.87	696	465	14	1	677	1	678	2e-79	279
rs:WP_027640180	DNA topoisomerase [Clostridium cadaveris].	33.06	599	358	14	1	587	1	568	2e-79	275
rs:WP_026703297	DNA topoisomerase III [Bacillus aidingensis].	31.96	657	385	21	3	626	5	632	2e-79	279
rs:WP_016190694	DNA topoisomerase III [Erwinia tracheiphila].	28.99	690	436	20	1	659	1	667	2e-79	278
rs:WP_022171745	DNA topoisomerase [Blautia sp. CAG:52].	31.15	655	400	20	3	626	4	638	2e-79	280
rs:WP_008672316	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	30.52	711	437	22	1	684	1	681	2e-79	279
rs:WP_040603203	DNA topoisomerase III [Paraprevotella xylaniphila].	30.37	642	390	14	1	598	1	629	2e-79	280
rs:WP_032843340	DNA topoisomerase I [Bacteroides ovatus].	29.33	699	450	19	1	677	1	677	2e-79	279
rs:WP_044137846	DNA topoisomerase I [Bacteroides oleiciplenus].	29.16	703	445	19	1	677	1	676	2e-79	279
rs:WP_045994683	DNA topoisomerase III [Halomonas sp. S2151].	30.00	610	386	14	1	581	1	598	2e-79	277
rs:WP_014110704	DNA topoisomerase III [Taylorella asinigenitalis].	31.44	741	401	28	3	680	5	701	2e-79	281
rs:WP_032496642	MULTISPECIES: DNA topoisomerase I [Bacteroides].	29.10	701	449	19	1	677	1	677	2e-79	279
rs:WP_025883495	DNA topoisomerase I [Porphyromonas uenonis].	31.02	693	430	20	4	673	5	672	2e-79	278
rs:WP_031811521	DNA topoisomerase III [Staphylococcus aureus].	32.70	636	374	18	3	615	4	608	2e-79	279
rs:WP_034978567	DNA topoisomerase I [Epilithonimonas lactis].	31.68	726	411	26	1	673	1	694	2e-79	279
rs:WP_021503851	DNA topoisomerase III [Serratia marcescens].	30.93	611	383	17	1	581	1	602	2e-79	277
rs:WP_026052510	DNA topoisomerase III [Gayadomonas joobiniege].	31.51	622	366	18	1	581	1	603	2e-79	277
rs:WP_002474079	DNA topoisomerase III [Staphylococcus epidermidis].	33.49	633	373	20	3	615	4	608	2e-79	279
rs:WP_039972867	DNA topoisomerase III [Bacteroides pyogenes].	31.13	652	369	18	1	588	1	636	2e-79	280
rs:WP_006785942	DNA topoisomerase [Turicibacter sanguinis].	30.29	713	448	21	3	687	4	695	2e-79	279
rs:WP_021772031	DNA topoisomerase [Mitsuokella sp. oral taxon 131].	28.96	670	429	15	1	640	1	653	2e-79	278
rs:WP_035604935	DNA topoisomerase III [Edwardsiella tarda].	30.34	613	384	18	1	581	1	602	2e-79	277
rs:WP_005357612	DNA topoisomerase III [Aeromonas veronii].	29.91	652	415	14	1	624	1	638	2e-79	278
rs:WP_012805984	DNA topoisomerase III [Pseudomonas putida].	30.26	651	409	15	1	614	1	643	2e-79	278
rs:WP_005691383	DNA topoisomerase III [Haemophilus influenzae].	31.46	623	377	17	1	583	1	613	2e-79	278
rs:WP_033641561	DNA topoisomerase III [Enterococcus faecium].	30.45	660	399	17	2	646	3	617	2e-79	278
rs:WP_025761771	DNA topoisomerase III [Dyadobacter tibetensis].	30.14	700	429	19	1	662	1	678	2e-79	279
tr:R9I6C5_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOS11739.1};	29.71	727	393	21	1	629	17	723	2e-79	279
tr:E5Y702_BILWA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.41	661	411	19	1	631	1	642	2e-79	280
rs:WP_013106257	DNA topoisomerase III [Thiomonas arsenitoxydans].	29.32	631	410	13	1	611	1	615	2e-79	279
rs:WP_026867002	DNA topoisomerase III [Jeotgalicoccus marinus].	31.18	651	393	20	3	627	5	626	2e-79	279
rs:WP_021118176	DNA topoisomerase III [Haemophilus parasuis].	30.77	624	390	17	1	592	1	614	2e-79	277
rs:WP_011716543	DNA topoisomerase III [Shewanella sp. ANA-3].	30.78	679	410	16	1	626	1	672	2e-79	279
tr:U7UHG3_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.28	601	344	16	3	587	29	594	2e-79	276
rs:WP_022583005	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.06	599	358	14	1	587	1	568	2e-79	275
rs:WP_039070763	DNA topoisomerase III [Brevibacillus borstelensis].	32.88	657	387	22	3	627	5	639	2e-79	279
rs:WP_015555481	DNA topoisomerase [Taylorella equigenitalis].	31.01	732	416	24	3	680	5	701	2e-79	281
rs:WP_010539317	DNA topoisomerase III [Bacteroides faecis].	31.04	625	383	15	1	588	1	614	2e-79	279
rs:WP_017799846	DNA topoisomerase III [Erwinia toletana].	31.07	647	390	21	1	608	1	630	2e-79	277
rs:WP_045756432	DNA topoisomerase I [Sphingobacterium sp. PM2-P1-29].	31.21	705	437	20	1	680	1	682	2e-79	278
rs:WP_013856386	DNA topoisomerase III [Vibrio anguillarum].	31.70	612	379	14	2	581	3	607	2e-79	277
rs:WP_021432698	DNA topoisomerase III family protein [[Clostridium] bifermentans].	32.32	659	370	23	3	631	5	617	2e-79	279
rs:WP_037587648	DNA topoisomerase III, partial [Stenoxybacter acetivorans].	31.92	589	345	17	41	581	3	583	2e-79	276
rs:WP_047296704	DNA topoisomerase III [Pseudomonas fluorescens].	27.80	669	436	15	1	638	1	653	2e-79	278
tr:C7LTI8_DESBD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.12	644	381	18	3	613	5	612	2e-79	276
rs:WP_003019459	DNA topoisomerase III [Blautia hansenii].	32.42	657	386	23	3	627	4	634	2e-79	279
rs:WP_038399531	topoisomerase [Staphylococcus epidermidis].	33.65	633	372	20	3	615	4	608	2e-79	279
rs:WP_035525287	DNA topoisomerase III [Haemophilus parasuis].	30.77	624	390	17	1	592	1	614	2e-79	277
rs:WP_006995139	MULTISPECIES: DNA topoisomerase III [Haemophilus].	31.19	622	380	16	1	583	1	613	2e-79	277
rs:WP_045495669	DNA topoisomerase I [Chryseobacterium sp. StRB126].	32.90	699	423	23	1	673	1	679	2e-79	278
rs:WP_005577632	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	29.45	669	411	19	1	630	1	647	2e-79	278
rs:WP_033643309	DNA topoisomerase III [Serratia marcescens].	30.93	611	383	17	1	581	1	602	2e-79	277
rs:WP_041214278	DNA topoisomerase III [Aeromonas caviae].	30.62	627	399	14	1	599	1	619	2e-79	278
rs:WP_025194984	DNA topoisomerase III [Streptococcus agalactiae].	34.40	593	340	15	3	580	5	563	2e-79	275
rs:WP_008721172	DNA topoisomerase III [Clostridiales bacterium 1_7_47FAA].	31.29	652	404	19	3	627	4	638	2e-79	279
rs:WP_034861907	DNA topoisomerase III [Enterobacteriaceae bacterium B14].	31.29	620	373	19	1	583	1	604	2e-79	277
rs:WP_024737330	DNA topoisomerase III [Clostridiales bacterium VE202-15].	31.23	666	391	22	3	627	4	643	2e-79	279
rs:WP_036293217	hypothetical protein [Methylobacter whittenburyi].	31.39	634	395	16	1	610	1	618	2e-79	278
rs:WP_042784710	DNA topoisomerase III [Serratia sp. SCBI].	30.93	611	383	17	1	581	1	602	2e-79	277
tr:U2CVP4_9BACE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERI88620.1};	31.13	652	369	18	1	588	17	652	2e-79	281
rs:WP_005794014	DNA topoisomerase I [Bacteroides fragilis].	28.88	703	450	18	1	676	1	680	2e-79	278
rs:WP_009291857	DNA topoisomerase I [Bacteroides sp. 2_1_56FAA].	28.12	697	462	15	1	677	1	678	2e-79	278
rs:WP_001175890	DNA topoisomerase III [Escherichia coli].	29.68	684	415	19	1	641	1	661	2e-79	278
rs:WP_007862391	DNA topoisomerase III [[Clostridium] citroniae].	29.40	704	444	19	1	676	1	679	2e-79	278
rs:WP_031893696	DNA topoisomerase III [Staphylococcus aureus].	32.70	636	374	18	3	615	4	608	2e-79	279
rs:WP_017243165	DNA topoisomerase III [Vibrio breoganii].	31.80	607	365	17	2	571	3	597	2e-79	277
rs:WP_032131993	DNA topoisomerase III [Weeksella sp. FF8].	31.00	713	432	21	1	678	1	688	2e-79	278
rs:WP_034946247	DNA topoisomerase III, partial [Gilliamella apicola].	31.18	619	378	15	2	581	8	617	2e-79	276
rs:WP_002571033	MULTISPECIES: DNA topoisomerase III [Lachnoclostridium].	29.79	705	432	22	2	670	5	682	2e-79	278
tr:A0A080LLZ6_9GAMM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.18	619	378	15	2	581	8	617	2e-79	277
rs:WP_008618622	DNA topoisomerase III [Paraprevotella clara].	30.37	642	390	14	1	598	1	629	2e-79	279
tr:A0A0C7RH49_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.43	666	360	24	3	631	5	617	2e-79	278
rs:WP_012004777	DNA topoisomerase III [Serratia proteamaculans].	29.49	607	396	11	1	581	1	601	2e-79	278
tr:K1FRK7_BACFG	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKA80127.1};	31.70	631	372	18	1	588	25	639	2e-79	279
tr:E2ZLR8_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.53	678	425	21	31	683	11	667	3e-79	278
rs:WP_021117221	DNA topoisomerase III family protein [Haemophilus parasuis].	29.33	641	413	10	1	614	1	628	3e-79	278
rs:WP_026858958	DNA topoisomerase III [Jeotgalicoccus psychrophilus].	30.97	649	396	18	3	627	5	625	3e-79	279
rs:WP_046061998	DNA topoisomerase III [Pseudomonas kilonensis].	28.10	669	434	17	1	638	1	653	3e-79	277
tr:D3AGG1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.79	705	432	22	2	670	7	684	3e-79	278
rs:WP_010532073	DNA topoisomerase III [Lentibacillus jeotgali].	31.27	630	397	15	3	615	5	615	3e-79	279
rs:WP_029434626	DNA topoisomerase III [Bilophila wadsworthia].	30.39	635	399	13	1	614	1	613	3e-79	278
rs:WP_041531187	hypothetical protein, partial [Persephonella marina].	33.72	602	339	20	1	577	1	567	3e-79	275
rs:WP_007836205	DNA topoisomerase III [Bacteroides dorei].	28.87	717	412	18	1	629	1	707	3e-79	278
rs:WP_012055035	DNA topoisomerase III [Haemophilus influenzae].	32.05	624	372	19	1	583	1	613	3e-79	277
tr:D4JA74_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.11	704	444	17	1	679	1	681	3e-79	278
rs:WP_019968966	DNA topoisomerase I [Prevotella maculosa].	30.69	707	435	24	1	677	1	682	3e-79	278
rs:WP_016913643	DNA topoisomerase III [Halomonas stevensii].	29.70	623	403	13	1	602	1	609	3e-79	277
rs:WP_031922391	DNA topoisomerase III, partial [Staphylococcus aureus].	32.55	636	375	18	3	615	4	608	3e-79	277
rs:WP_021371256	DNA topoisomerase III family protein [Peptoclostridium difficile].	33.06	599	358	14	1	587	1	568	3e-79	275
rs:WP_042064235	DNA topoisomerase III [Aeromonas hydrophila].	29.95	651	413	16	1	623	1	636	3e-79	277
rs:WP_024213397	DNA topoisomerase III [Escherichia coli].	29.68	684	415	19	1	641	1	661	3e-79	278
rs:WP_009500211	DNA topoisomerase III [Haemophilus sp. oral taxon 851].	32.05	624	372	19	1	583	1	613	3e-79	277
rs:WP_030132226	DNA topoisomerase III [Pseudomonas sp. QTF5].	28.87	665	416	16	1	629	1	644	3e-79	278
rs:WP_043004022	DNA topoisomerase III, partial [Vibrio anguillarum].	30.55	622	362	18	1	574	1	600	3e-79	276
rs:WP_034103292	DNA topoisomerase III [Pseudomonas fluorescens].	27.87	671	433	16	1	638	1	653	3e-79	277
rs:WP_008776282	DNA topoisomerase III [Bacteroides sp. 2_2_4].	31.20	625	382	15	1	588	1	614	3e-79	279
rs:WP_016223842	DNA topoisomerase III [Lachnospiraceae bacterium 3-2].	29.71	700	436	20	1	670	1	674	3e-79	278
rs:WP_009490444	DNA topoisomerase III [Catellicoccus marimammalium].	30.62	725	427	20	3	673	4	706	3e-79	278
rs:WP_021320572	DNA topoisomerase [Streptococcus equi].	33.83	600	352	15	1	587	1	568	3e-79	275
rs:WP_025115491	DNA topoisomerase III [Lysinibacillus fusiformis].	33.68	668	367	29	3	627	5	639	3e-79	279
rs:WP_014753667	DNA topoisomerase III [Pseudomonas putida].	29.08	643	405	13	1	614	1	621	3e-79	277
rs:WP_012073435	DNA topoisomerase III [Actinobacillus succinogenes].	31.99	619	369	20	1	581	1	605	3e-79	277
rs:WP_033010883	DNA topoisomerase III [Geobacillus stearothermophilus].	29.03	720	462	20	1	681	1	710	3e-79	278
rs:WP_007469989	DNA topoisomerase III [Photobacterium sp. AK15].	31.59	611	373	15	2	578	3	602	3e-79	277
rs:WP_009893975	MULTISPECIES: DNA topoisomerase [Firmicutes].	33.06	599	358	14	1	587	1	568	3e-79	275
rs:WP_036191270	DNA topoisomerase III [Marinobacterium sp. AK27].	31.16	613	377	14	1	581	1	600	3e-79	277
rs:WP_044909789	DNA topoisomerase III [Lachnospiraceae bacterium MC2017].	30.37	698	431	23	1	671	1	670	3e-79	278
rs:WP_008650257	DNA topoisomerase III [Bacteroides sp. 3_1_23].	31.20	625	382	15	1	588	1	614	3e-79	279
rs:WP_012089582	DNA topoisomerase III [Shewanella baltica].	30.54	645	383	15	1	591	1	634	3e-79	278
rs:WP_039147192	DNA topoisomerase III [Gallibacterium anatis].	31.35	622	376	16	1	581	1	612	3e-79	277
rs:WP_014606859	DNA topoisomerase III [Pantoea ananatis].	28.61	664	422	14	1	629	1	647	3e-79	277
rs:WP_010193780	DNA topoisomerase III [Bacillus sp. m3-13].	30.49	728	439	20	1	675	1	714	3e-79	278
tr:F3QYD9_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EGG50486.1};	30.37	642	390	14	1	598	34	662	3e-79	280
rs:WP_024994449	DNA topoisomerase III [Bacteroides paurosaccharolyticus].	30.20	702	408	19	1	630	1	692	3e-79	278
rs:WP_034316017	DNA topoisomerase III [Bacillus simplex].	31.71	637	393	17	3	615	5	623	3e-79	279
rs:WP_023389097	DNA topoisomerase III [Youngiibacter fragilis].	30.06	652	400	17	3	627	5	627	3e-79	278
rs:WP_022471349	DNA topoisomerase III [Bacteroides thetaiotaomicron CAG:40].	31.20	625	382	15	1	588	1	614	3e-79	278
rs:WP_008704037	DNA topoisomerase III [Ruminococcus sp. 5_1_39BFAA].	31.11	659	401	18	3	627	4	643	3e-79	279
rs:WP_046337374	DNA topoisomerase III [Xenorhabdus bovienii].	30.06	642	403	17	1	614	1	624	3e-79	277
rs:WP_021663186	DNA topoisomerase, partial [Porphyromonas gingivalis].	30.35	692	412	22	1	651	1	663	3e-79	277
rs:WP_042147034	DNA topoisomerase III [Paucisalibacillus sp. EB02].	30.54	632	403	16	3	615	5	619	4e-79	278
rs:WP_004245767	DNA topoisomerase III [Proteus mirabilis].	29.78	648	409	14	1	616	1	634	4e-79	278
tr:A0A0E2SB13_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EXZ62045.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EXZ62045.1};	30.57	700	375	22	28	629	13	699	4e-79	278
rs:WP_027130995	DNA topoisomerase [Gemella cuniculi].	33.84	597	354	14	2	587	4	570	4e-79	275
rs:WP_008778183	DNA topoisomerase I [Parabacteroides sp. 20_3].	30.16	703	441	22	1	676	1	680	4e-79	278
rs:WP_006566731	MULTISPECIES: DNA topoisomerase III [Anaerostipes].	30.98	652	385	19	2	627	4	616	4e-79	278
rs:WP_013632693	DNA topoisomerase [Pedobacter saltans].	31.90	699	425	24	1	673	1	674	4e-79	278
rs:WP_013737914	DNA topoisomerase [Metallosphaera cuprina].	29.01	724	423	23	1	681	1	676	4e-79	277
rs:WP_022221047	DNA topoisomerase [Coprococcus comes CAG:19].	31.94	670	384	21	3	627	4	646	4e-79	278
rs:WP_011411189	DNA topoisomerase III [Sodalis glossinidius].	30.34	613	384	16	1	581	1	602	4e-79	276
rs:WP_029216649	DNA topoisomerase I [Prevotella denticola].	30.66	698	441	19	4	684	5	676	4e-79	278
rs:WP_033636010	DNA topoisomerase III [Serratia marcescens].	29.82	607	394	10	1	581	1	601	4e-79	277
rs:WP_007766830	DNA topoisomerase III [Bacteroides finegoldii].	29.68	711	408	18	1	629	1	701	4e-79	278
rs:WP_033643829	MULTISPECIES: DNA topoisomerase III [Enterococcus].	30.40	658	398	17	2	644	3	615	4e-79	278
rs:WP_021462028	DNA topoisomerase III [Gallibacterium anatis].	30.31	617	382	16	1	585	1	601	4e-79	276
rs:WP_005626523	DNA topoisomerase III [Haemophilus haemolyticus].	31.41	624	376	17	1	583	1	613	4e-79	276
rs:WP_034727120	DNA topoisomerase I [Chryseobacterium sp. JM1].	31.02	706	422	23	1	673	1	674	4e-79	278
rs:WP_031932480	DNA topoisomerase III [Brevibacillus borstelensis].	32.88	657	387	22	3	627	5	639	4e-79	278
rs:WP_004335184	DNA topoisomerase I [Porphyromonas endodontalis].	30.10	701	435	21	3	677	4	675	4e-79	278
rs:WP_036078130	DNA topoisomerase III [Lysinibacillus boronitolerans].	33.88	670	363	26	3	627	5	639	4e-79	278
tr:A0A098ETD9_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.86	623	386	15	3	611	7	592	4e-79	278
tr:A0A0D8IWN4_9FIRM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KJF39097.1};	30.63	653	394	20	1	627	1	620	4e-79	278
rs:WP_008930006	DNA topoisomerase III [Alcanivorax hongdengensis].	29.16	679	425	19	1	640	1	662	4e-79	277
rs:WP_017042547	DNA topoisomerase III [Vibrio ordalii].	31.97	613	376	15	2	581	3	607	4e-79	276
rs:WP_025214466	DNA topoisomerase III [Pseudomonas brassicacearum].	27.99	668	437	15	1	638	1	654	4e-79	277
rs:WP_010803479	MULTISPECIES: DNA topoisomerase III [Parabacteroides].	28.69	697	458	15	1	677	1	678	4e-79	278
rs:WP_002304230	DNA topoisomerase III [Enterococcus faecium].	30.40	658	398	17	2	644	3	615	4e-79	278
rs:WP_033829617	DNA topoisomerase III [Bacillus sp. KW-12].	29.54	721	458	20	1	681	1	711	4e-79	278
rs:WP_025483685	DNA topoisomerase III [Clostridiales bacterium VE202-28].	31.13	652	405	19	3	627	4	638	4e-79	278
rs:WP_032537012	MULTISPECIES: DNA topoisomerase III [Bacteroides].	31.70	631	372	18	1	588	1	615	4e-79	278
rs:WP_018341696	DNA topoisomerase III [Cytophaga aurantiaca].	29.79	705	441	18	1	662	1	694	4e-79	278
rs:WP_033612353	DNA topoisomerase III [Enterococcus faecium].	30.24	658	399	17	2	644	3	615	4e-79	277
rs:WP_013523825	MULTISPECIES: DNA topoisomerase III [Geobacillus].	28.87	717	467	20	1	681	1	710	4e-79	278
rs:WP_042262170	DNA topoisomerase III [Clostridium perfringens].	32.52	658	387	21	2	627	6	638	4e-79	278
rs:WP_004351990	DNA topoisomerase I [Prevotella denticola].	30.28	710	434	25	1	677	1	682	4e-79	278
rs:WP_033572507	DNA topoisomerase I [Bacteroides sp. UW].	28.96	701	450	19	1	677	1	677	4e-79	278
tr:A0A0A8LKP9_XENNE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.31	640	407	14	1	614	7	633	4e-79	277
rs:WP_046832941	DNA topoisomerase [Xanthomonas axonopodis].	30.32	653	406	16	1	614	1	643	5e-79	277
rs:WP_005781365	DNA topoisomerase III [Bacteroides fragilis].	31.70	631	372	18	1	588	1	615	5e-79	278
rs:WP_043165453	DNA topoisomerase III [Aeromonas hydrophila].	29.75	652	415	16	1	624	1	637	5e-79	277
rs:WP_000765274	DNA topoisomerase III [Escherichia coli].	29.63	648	410	14	1	616	1	634	5e-79	277
rs:WP_005641248	DNA topoisomerase III [Haemophilus haemolyticus].	32.37	624	370	19	1	583	1	613	5e-79	276
rs:WP_044705513	DNA topoisomerase III [Escherichia coli].	29.64	685	414	19	1	641	1	661	5e-79	277
rs:WP_041209572	DNA topoisomerase III [Aeromonas jandaei].	29.37	664	403	17	1	624	1	638	5e-79	277
rs:WP_035496709	DNA topoisomerase III [Haemophilus parasuis].	30.77	624	390	17	1	592	1	614	5e-79	276
rs:WP_004342576	DNA topoisomerase I [Prevotella buccae].	31.03	696	425	19	4	673	5	671	5e-79	277
rs:WP_002144421	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.19	722	440	23	3	680	4	705	5e-79	278
rs:WP_034433748	DNA topoisomerase [Clostridiales bacterium S5-A14a].	34.51	594	338	16	3	580	5	563	5e-79	274
tr:K6AE20_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKN21946.1};	28.98	697	449	19	4	677	5	678	5e-79	278
rs:WP_038439372	DNA topoisomerase III [Haemophilus influenzae].	31.41	624	376	18	1	583	1	613	5e-79	276
rs:WP_028071503	DNA topoisomerase I [Sphingobacterium thalpophilum].	31.47	715	432	24	1	676	1	696	5e-79	278
rs:WP_011866096	DNA topoisomerase III [Shewanella loihica].	31.19	638	373	18	1	589	1	621	5e-79	277
rs:WP_004321870	MULTISPECIES: DNA topoisomerase III [Bacteroides].	31.20	625	382	15	1	588	1	614	5e-79	278
rs:WP_036176604	DNA topoisomerase III [Lysinibacillus massiliensis].	29.35	719	466	16	3	682	5	720	5e-79	278
rs:WP_027857709	DNA topoisomerase III [Marinobacterium jannaschii].	30.76	634	390	15	1	599	1	620	5e-79	276
rs:WP_004239734	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	29.63	648	410	14	1	616	1	634	5e-79	277
rs:WP_034567039	DNA topoisomerase III [Clostridiales bacterium VE202-03].	29.14	700	441	19	1	671	1	674	5e-79	277
rs:WP_011222097	DNA topoisomerase [uncultured bacterium].	30.11	651	410	15	1	614	1	643	5e-79	277
tr:B1RGM1_CLOPF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.52	658	387	21	2	627	3	635	5e-79	278
rs:WP_008775022	DNA topoisomerase I [Bacteroides sp. 2_2_4].	29.25	711	448	20	1	684	1	683	5e-79	277
rs:WP_039161879	DNA topoisomerase III [Gallibacterium anatis].	30.78	627	373	16	1	581	1	612	5e-79	276
rs:WP_009276709	MULTISPECIES: DNA topoisomerase I [Parabacteroides].	28.88	703	454	16	1	678	24	705	5e-79	278
rs:WP_005861699	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	30.52	711	437	22	1	684	1	681	5e-79	277
rs:WP_023859599	DNA topoisomerase III [Lactobacillus equi].	31.68	625	371	15	2	614	4	584	5e-79	277
tr:K9E6L5_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKU91481.1};	29.14	700	443	19	4	677	5	677	5e-79	277
rs:WP_004252369	DNA topoisomerase III [Proteus mirabilis].	29.63	648	410	14	1	616	1	634	5e-79	277
rs:WP_023058387	MULTISPECIES: DNA topoisomerase [Prevotella].	31.06	718	440	24	1	684	1	697	5e-79	278
rs:WP_022233792	DNA topoisomerase TopB [Bacteroides sp. CAG:443].	30.39	701	435	22	1	676	1	673	5e-79	277
rs:WP_014343684	DNA topoisomerase III [Aliivibrio fischeri].	29.08	698	438	19	1	659	1	680	5e-79	278
rs:WP_046823179	DNA topoisomerase III [Clostridium sp. JC272].	32.17	659	371	23	3	631	5	617	6e-79	278
rs:WP_026821966	DNA topoisomerase III [Arsenophonus nasoniae].	31.31	610	380	15	2	581	3	603	6e-79	276
rs:WP_021652294	DNA topoisomerase [Blautia sp. KLE 1732].	31.52	663	390	18	3	627	4	640	6e-79	278
rs:WP_004326163	DNA topoisomerase III [Bacteroides ovatus].	31.20	625	382	15	1	588	1	614	6e-79	278
rs:WP_023612253	DNA topoisomerase III [Streptococcus pyogenes].	34.51	594	338	16	3	580	5	563	6e-79	274
rs:WP_016220727	DNA topoisomerase III [Dorea sp. 5-2].	29.67	701	437	21	1	671	1	675	6e-79	277
rs:WP_026742443	DNA topoisomerase III [Lonsdalea quercina].	30.78	614	375	17	1	578	1	600	6e-79	276
rs:WP_033629071	DNA topoisomerase III [Enterococcus faecium].	30.40	658	398	17	2	644	3	615	6e-79	277
rs:WP_031612074	DNA topoisomerase III, partial [Salmonella enterica].	32.25	583	356	18	31	581	1	576	6e-79	275
rs:WP_008766576	DNA topoisomerase III [Bacteroides sp. 1_1_6].	31.20	625	382	15	1	588	1	614	6e-79	278
rs:WP_033584975	DNA topoisomerase III [Enterococcus faecium].	30.40	658	398	17	2	644	3	615	6e-79	277
rs:WP_033655380	DNA topoisomerase III [Enterococcus faecium].	30.40	658	398	17	2	644	3	615	6e-79	277
rs:WP_004312405	DNA topoisomerase III [Bacteroides ovatus].	31.20	625	382	15	1	588	1	614	6e-79	278
tr:B7JBJ6_ACIF2	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.91	652	417	19	1	625	1	639	6e-79	277
rs:WP_033581948	DNA topoisomerase III [Enterococcus faecium].	30.40	658	398	17	2	644	3	615	6e-79	277
rs:WP_016183792	DNA topoisomerase III [Enterococcus columbae].	31.42	627	369	18	2	611	3	585	6e-79	277
rs:WP_033602639	DNA topoisomerase III [Enterococcus faecium].	30.40	658	398	17	2	644	3	615	6e-79	277
rs:WP_025950588	DNA topoisomerase III [Geobacillus thermocatenulatus].	29.99	667	398	19	3	646	4	624	6e-79	277
rs:WP_033884893	DNA topoisomerase III [Escherichia coli].	30.02	643	398	16	1	610	1	624	6e-79	277
rs:WP_003398165	DNA topoisomerase III [Anoxybacillus flavithermus].	30.37	731	436	27	1	681	1	708	6e-79	278
tr:N0DXA8_STRPY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.63	715	433	19	3	673	4	699	6e-79	277
rs:WP_017111130	DNA topoisomerase III [Vibrio tasmaniensis].	31.00	613	384	12	2	581	3	609	6e-79	276
rs:WP_033131258	DNA topoisomerase III [Aeromonas sp. AE235].	30.30	627	401	13	1	599	1	619	7e-79	276
rs:WP_022199129	DNA topoisomerase III [Bacteroides ovatus CAG:22].	31.20	625	382	15	1	588	1	614	7e-79	278
tr:F7LKF0_9BACE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGN04413.1};	29.08	698	447	19	4	677	5	678	7e-79	277
rs:WP_033795582	DNA topoisomerase III [Enterococcus faecium].	30.40	658	398	17	2	644	3	615	7e-79	277
rs:WP_033795073	DNA topoisomerase III [Enterococcus faecium].	30.40	658	398	17	2	644	3	615	7e-79	277
rs:WP_039702391	DNA topoisomerase III [Staphylococcus aureus].	32.70	636	374	18	3	615	4	608	7e-79	277
rs:WP_031833188	DNA topoisomerase III [Staphylococcus aureus].	32.70	636	374	18	3	615	4	608	7e-79	277
rs:WP_010385040	DNA topoisomerase III [Pseudoalteromonas rubra].	31.76	592	359	14	1	560	1	579	7e-79	276
rs:WP_021118952	DNA topoisomerase III [Haemophilus parasuis].	30.77	624	390	17	1	592	1	614	7e-79	276
rs:WP_000779855	DNA topoisomerase [Streptococcus pneumoniae].	35.22	582	322	16	1	564	1	545	7e-79	274
rs:WP_018357839	DNA topoisomerase I [Porphyromonas levii].	31.23	698	422	22	4	673	5	672	7e-79	277
rs:WP_016268580	DNA topoisomerase III [Bacteroides thetaiotaomicron].	31.20	625	382	15	1	588	1	614	7e-79	278
rs:WP_039178370	DNA topoisomerase III [Halomonas hydrothermalis].	29.70	623	403	13	1	602	1	609	7e-79	276
rs:WP_008370080	DNA topoisomerase III [Coprococcus comes].	31.94	670	384	21	3	627	4	646	7e-79	278
rs:WP_044743437	DNA topoisomerase III [Anoxybacillus sp. ATCC BAA-2555].	30.19	722	450	22	1	681	1	709	7e-79	277
tr:A0A0B0VM59_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.64	685	414	19	1	641	1	661	7e-79	276
rs:WP_008816736	DNA topoisomerase III [Erysipelotrichaceae bacterium 6_1_45].	28.94	705	446	19	1	676	1	679	7e-79	277
rs:WP_008665854	DNA topoisomerase I [Bacteroides sp. 4_1_36].	29.86	710	444	21	1	684	1	682	8e-79	277
tr:A7LZL4_BACO1	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EDO11386.1};	31.20	625	382	15	1	588	1	614	8e-79	278
rs:WP_025188549	DNA topoisomerase [Enterococcus faecalis].	34.29	595	338	17	3	580	5	563	8e-79	274
rs:WP_032459628	DNA topoisomerase III [Streptococcus agalactiae].	34.34	594	339	16	3	580	5	563	8e-79	274
rs:WP_007708551	DNA topoisomerase III [[Clostridium] asparagiforme].	31.08	666	392	22	3	627	4	643	8e-79	278
rs:WP_041647363	DNA topoisomerase III, partial [Acidithiobacillus ferrooxidans].	29.92	645	413	18	1	619	1	632	8e-79	275
rs:WP_031515700	DNA topoisomerase III [Desulfotomaculum alkaliphilum].	31.12	649	407	18	3	627	5	637	8e-79	278
rs:WP_006082217	DNA topoisomerase III [Shewanella baltica].	30.54	645	383	15	1	591	1	634	8e-79	277
rs:WP_003388716	DNA topoisomerase III [Brevibacillus borstelensis].	32.72	657	388	22	3	627	5	639	8e-79	278
rs:WP_005646774	DNA topoisomerase III [Haemophilus haemolyticus].	31.09	624	378	17	1	583	1	613	8e-79	276
rs:WP_041981894	DNA topoisomerase III [Xenorhabdus nematophila].	30.31	640	407	14	1	614	1	627	8e-79	276
rs:WP_044008984	DNA topoisomerase III [Haemophilus parasuis].	31.30	623	388	17	1	592	1	614	8e-79	275
tr:K1G861_BACFG	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKA90429.1};	31.70	631	372	18	1	588	25	639	8e-79	278
rs:WP_022066773	DNA topoisomerase III [Blautia sp. CAG:257].	31.15	655	402	18	3	627	4	639	8e-79	278
rs:WP_044187714	DNA topoisomerase III [Escherichia coli].	29.68	684	415	19	1	641	1	661	8e-79	276
rs:WP_042267858	DNA topoisomerase III [Clostridium perfringens].	32.52	658	387	21	2	627	6	638	9e-79	278
rs:WP_004306716	MULTISPECIES: DNA topoisomerase III [Bacteroides].	31.20	625	382	15	1	588	1	614	9e-79	277
rs:WP_023267714	DNA topoisomerase III [Shewanella decolorationis].	31.64	629	375	15	1	581	1	622	9e-79	277
rs:WP_026350873	DNA topoisomerase III [Dyadobacter beijingensis].	29.91	702	433	18	1	661	1	684	9e-79	277
rs:WP_004054601	DNA topoisomerase III [Eubacterium plexicaudatum].	29.53	701	438	20	1	671	1	675	9e-79	277
rs:WP_039084901	DNA topoisomerase III [Gallibacterium anatis].	30.62	627	374	16	1	581	1	612	9e-79	276
rs:WP_025950702	DNA topoisomerase III [Geobacillus thermocatenulatus].	28.83	718	466	21	1	681	1	710	9e-79	277
rs:WP_008759804	DNA topoisomerase III [Bacteroides sp. 1_1_14].	31.20	625	382	15	1	588	1	614	9e-79	277
rs:WP_034934415	DNA topoisomerase III [Erwinia mallotivora].	29.73	602	382	13	1	572	1	591	9e-79	276
rs:WP_044393261	DNA topoisomerase III [Bacillus subterraneus].	28.53	722	464	18	1	681	1	711	9e-79	277
rs:WP_031943161	TraE DNA topoisomerase [uncultured bacterium].	29.19	716	445	18	1	671	1	699	9e-79	278
tr:Q8XK95_CLOPE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.52	658	387	21	2	627	3	635	9e-79	278
sp:TOP3_HAEIN	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	31.57	624	375	18	1	583	1	613	9e-79	276
rs:WP_020959817	DNA topoisomerase III [Geobacillus sp. JF8].	29.35	661	409	17	3	646	4	623	9e-79	277
rs:WP_005643883	DNA topoisomerase I [Parabacteroides merdae].	30.30	703	440	22	1	676	1	680	9e-79	277
rs:WP_031527797	DNA topoisomerase III [Dyadobacter crusticola].	29.59	703	434	20	1	661	1	684	9e-79	277
rs:WP_041510970	DNA topoisomerase III [Shewanella sp. cp20].	31.60	636	373	19	1	589	1	621	9e-79	276
rs:WP_034820565	DNA topoisomerase [[Eubacterium] nodatum].	33.39	599	356	15	1	587	1	568	9e-79	273
rs:WP_042265979	DNA topoisomerase III [Clostridium perfringens].	32.52	658	387	21	2	627	6	638	9e-79	278
rs:WP_033624436	DNA topoisomerase III [Enterococcus faecium].	30.24	658	399	17	2	644	3	615	9e-79	276
rs:WP_039155132	DNA topoisomerase III [Gallibacterium anatis].	30.78	627	373	16	1	581	1	612	1e-78	275
rs:WP_015237730	DNA topoisomerase III [Kinetoplastibacterium blastocrithidii].	31.57	738	408	29	2	680	4	703	1e-78	279
tr:A0A0E2RW48_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EXZ52234.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EXZ52234.1};	30.57	700	375	22	28	629	13	699	1e-78	277
rs:WP_042082863	DNA topoisomerase III [Aeromonas veronii].	29.60	652	417	13	1	624	1	638	1e-78	276
rs:WP_026683476	DNA topoisomerase III [Bacillus coagulans].	29.42	724	453	20	3	683	5	713	1e-78	277
rs:WP_004086664	DNA topoisomerase [Xylella fastidiosa].	31.01	674	413	19	1	630	1	666	1e-78	276
rs:WP_007886640	DNA topoisomerase III [Roseburia inulinivorans].	29.33	699	439	19	2	671	5	677	1e-78	277
rs:WP_028298779	DNA topoisomerase I [Olivibacter sitiensis].	31.16	706	435	22	1	680	1	681	1e-78	276
rs:WP_004820017	DNA topoisomerase [Peptoniphilus indolicus].	34.22	599	351	15	1	587	1	568	1e-78	273
tr:B1R566_CLOPF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.52	658	387	21	2	627	3	635	1e-78	277
rs:WP_013811158	MULTISPECIES: DNA topoisomerase III [Serratia].	29.65	607	395	12	1	581	1	601	1e-78	276
rs:WP_033698011	DNA topoisomerase III [Enterococcus faecium].	30.40	658	398	17	2	644	3	615	1e-78	276
rs:WP_024564950	DNA topoisomerase [Elizabethkingia anophelis].	30.63	702	437	20	1	680	1	674	1e-78	276
rs:WP_041982760	DNA topoisomerase III [Xenorhabdus nematophila].	30.54	668	410	16	1	633	1	649	1e-78	276
rs:WP_002317775	DNA topoisomerase III [Enterococcus faecium].	30.24	658	399	17	2	644	3	615	1e-78	276
rs:WP_026320152	DNA topoisomerase III [Bacteroides barnesiae].	30.40	648	397	14	1	608	1	634	1e-78	277
rs:WP_046953220	DNA topoisomerase III [Haemophilus haemolyticus].	32.32	625	369	21	1	583	1	613	1e-78	275
rs:WP_044230524	DNA topoisomerase I [Coprobacter sp. 177].	28.12	697	461	16	1	677	1	677	1e-78	276
rs:WP_034631803	DNA topoisomerase III [Bacillus okhensis].	29.90	719	456	18	1	681	1	709	1e-78	277
tr:C2BD67_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.66	698	428	18	1	673	5	664	1e-78	276
rs:WP_044731338	DNA topoisomerase III [Geobacillus kaustophilus].	29.17	665	405	17	3	646	4	623	1e-78	276
rs:WP_021966620	DNA topoisomerase [Clostridium sp. CAG:149].	30.31	673	403	18	3	627	4	658	1e-78	278
rs:WP_015900982	DNA topoisomerase III [Staphylococcus carnosus].	33.02	636	371	18	3	615	4	607	1e-78	277
rs:WP_036868535	MULTISPECIES: DNA topoisomerase I [Porphyromonas].	29.76	699	444	19	1	676	1	675	1e-78	276
rs:WP_021116949	DNA topoisomerase III [Haemophilus parasuis].	30.77	624	390	17	1	592	1	614	1e-78	275
rs:WP_029141629	DNA topoisomerase III [Bacillus coagulans].	29.71	727	447	20	3	683	5	713	1e-78	277
rs:WP_021519870	hypothetical protein [Escherichia coli].	29.53	684	416	19	1	641	1	661	1e-78	276
rs:WP_032823989	DNA topoisomerase III [Haemophilus influenzae].	31.84	625	372	20	1	583	1	613	1e-78	275
tr:R5HVF0_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.90	657	401	18	3	627	4	639	1e-78	277
tr:G5GKY2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.13	589	333	16	3	571	20	573	1e-78	274
rs:WP_006661664	DNA topoisomerase III [Providencia alcalifaciens].	31.04	625	377	18	1	583	1	613	1e-78	275
tr:B1V109_CLOPF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.52	658	387	21	2	627	3	635	1e-78	277
rs:WP_005285122	DNA topoisomerase III [Edwardsiella tarda].	30.18	613	385	18	1	581	1	602	1e-78	275
rs:WP_040214331	DNA topoisomerase III [Clostridium sp. MS1].	31.29	636	394	17	3	615	5	620	1e-78	277
rs:WP_012457228	DNA topoisomerase I [Porphyromonas gingivalis].	30.32	719	444	24	1	684	1	697	1e-78	277
rs:WP_007751728	DNA topoisomerase III [Bacteroides finegoldii].	29.60	706	411	18	1	629	1	697	1e-78	276
rs:WP_043014029	DNA topoisomerase III [Clostridium perfringens].	32.52	658	387	21	2	627	6	638	1e-78	277
rs:WP_012535949	DNA topoisomerase III [Acidithiobacillus ferrooxidans].	29.49	651	421	16	1	625	1	639	1e-78	276
tr:J6BME1_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.29	595	338	17	3	580	41	599	1e-78	274
rs:WP_017027834	DNA topoisomerase III [Vibrio breoganii].	31.80	610	364	17	2	571	3	600	1e-78	275
rs:WP_039042718	DNA topoisomerase III [Sporosarcina sp. ZBG7A].	32.57	651	391	19	3	627	5	633	1e-78	277
rs:WP_021110768	DNA topoisomerase III [Haemophilus parasuis].	30.77	624	390	17	1	592	1	614	1e-78	275
rs:WP_045167309	DNA topoisomerase I [Prevotella intermedia].	30.04	689	441	18	1	673	2	665	1e-78	276
rs:WP_004293951	DNA topoisomerase III [Bacteroides eggerthii].	30.17	653	391	17	1	603	1	638	1e-78	277
rs:WP_021940547	DNA topoisomerase III [Bacteroides eggerthii CAG:109].	30.17	653	391	17	1	603	1	638	1e-78	277
rs:WP_039861625	DNA topoisomerase III [Lachnospiraceae bacterium 6_1_37FAA].	31.85	653	402	20	3	626	4	642	1e-78	277
rs:WP_021724503	DNA topoisomerase III [Avibacterium paragallinarum].	31.72	640	388	19	1	605	1	626	1e-78	275
rs:WP_020999844	DNA topoisomerase III [Streptococcus anginosus].	33.90	587	347	13	1	576	1	557	1e-78	273
rs:WP_036894906	DNA topoisomerase I [Prevotella sp. S7-1-8].	30.13	707	424	21	1	673	2	672	1e-78	276
rs:WP_004346359	DNA topoisomerase I [Prevotella buccae].	30.27	697	446	18	4	684	5	677	1e-78	276
rs:WP_008617926	DNA topoisomerase I [Paraprevotella clara].	30.96	701	431	22	1	676	1	673	1e-78	276
rs:WP_022230671	DNA topoisomerase [Firmicutes bacterium CAG:41].	29.65	678	443	15	1	664	1	658	1e-78	276
rs:WP_005659784	DNA topoisomerase III [Haemophilus influenzae].	31.41	624	376	18	1	583	1	613	1e-78	275
rs:WP_033757863	DNA topoisomerase III [Pantoea agglomerans].	30.94	627	362	18	1	581	1	602	1e-78	275
rs:WP_017107363	DNA topoisomerase III [Vibrio tasmaniensis].	31.11	614	382	13	2	581	3	609	1e-78	275
rs:WP_004575589	DNA topoisomerase III [Pseudomonas putida].	27.87	671	437	14	1	641	1	654	1e-78	275
rs:WP_004288554	DNA topoisomerase III [Bacteroides eggerthii].	30.17	653	391	17	1	603	1	638	1e-78	277
tr:Q0SSU9_CLOPS	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.52	658	387	21	2	627	6	638	1e-78	277
rs:WP_034834689	DNA topoisomerase III [Clostridium perfringens].	32.52	658	387	21	2	627	6	638	1e-78	277
rs:WP_033606477	DNA topoisomerase III [Enterococcus faecium].	30.40	658	398	17	2	644	3	615	1e-78	276
rs:WP_045989685	DNA topoisomerase III [Pseudoalteromonas piscicida].	31.75	611	371	15	1	578	1	598	1e-78	275
rs:WP_036739241	DNA topoisomerase [Peptoniphilus sp. BV3C26].	34.34	594	339	16	3	580	5	563	1e-78	273
rs:WP_012933280	DNA topoisomerase III [Conexibacter woesei].	27.70	722	456	22	3	678	5	706	1e-78	278
rs:WP_033643474	DNA topoisomerase III [Enterococcus faecium].	30.29	657	400	17	2	644	3	615	1e-78	276
gp:CP003909_766	DNA topoisomerase III [Neisseria gonorrhoeae MS11]	31.75	630	371	19	30	610	9	628	1e-78	275
rs:WP_018920050	DNA topoisomerase I [Prevotella oris].	30.60	719	442	24	1	684	1	697	1e-78	276
rs:WP_045953833	DNA topoisomerase III [Vibrio sp. S2757].	32.42	620	364	18	2	581	3	607	1e-78	275
rs:WP_026917064	DNA topoisomerase III [Haemophilus parasuis].	31.30	623	388	17	1	592	1	614	1e-78	275
rs:WP_034617905	DNA topoisomerase III [Chelonobacter oris].	31.22	647	384	20	1	605	1	628	1e-78	275
rs:WP_024362789	DNA topoisomerase III [Lysinibacillus sphaericus].	32.73	660	384	23	3	627	5	639	1e-78	277
rs:WP_008759619	DNA topoisomerase I [Bacteroides sp. 1_1_14].	30.52	711	436	23	1	684	1	680	1e-78	276
rs:WP_024981683	DNA topoisomerase I [Flavobacterium succinicans].	32.30	675	394	23	1	643	1	644	1e-78	276
rs:WP_031622230	DNA topoisomerase III, partial [Salmonella enterica].	32.25	583	356	18	31	581	12	587	1e-78	275
rs:WP_039095869	DNA topoisomerase III [Gallibacterium anatis].	30.78	627	373	16	1	581	1	612	1e-78	275
tr:S6JIF2_PSEST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.19	716	445	18	1	671	1	699	1e-78	277
rs:WP_031592756	DNA topoisomerase III [Pantoea agglomerans].	31.05	628	360	19	1	581	1	602	1e-78	275
rs:WP_043812033	DNA topoisomerase III, partial [Desulfomicrobium baculatum].	31.59	592	348	16	3	561	5	572	1e-78	273
rs:WP_033003857	DNA topoisomerase III, partial [Vibrio azureus].	30.82	662	405	18	1	630	1	641	1e-78	276
rs:WP_004394830	DNA topoisomerase III [Vibrio metschnikovii].	30.44	611	386	13	2	580	3	606	1e-78	275
rs:WP_027607351	DNA topoisomerase III [Pseudomonas sp. LAMO17WK12:I2].	28.46	664	428	16	1	633	1	648	1e-78	275
rs:WP_031204974	DNA topoisomerase III, partial [Gallibacterium anatis].	30.34	613	379	16	1	581	1	597	2e-78	274
rs:WP_033779068	DNA topoisomerase III [Pantoea agglomerans].	30.94	627	362	18	1	581	1	602	2e-78	275
rs:WP_041137912	DNA topoisomerase III [Clostridiaceae bacterium GM1].	32.16	653	392	20	3	627	5	634	2e-78	277
rs:WP_042012256	DNA topoisomerase III [Aeromonas fluvialis].	29.45	652	418	13	1	624	1	638	2e-78	275
rs:WP_047211463	DNA topoisomerase [Streptococcus agalactiae].	33.56	599	355	15	1	587	1	568	2e-78	273
rs:WP_033696774	DNA topoisomerase III [Enterococcus faecium].	30.40	658	398	17	2	644	3	615	2e-78	276
rs:WP_042654335	DNA topoisomerase III [Aeromonas encheleia].	29.57	646	393	16	1	604	1	626	2e-78	275
rs:WP_026557375	DNA topoisomerase III [Bacillus sp. NSP2.1].	29.16	734	456	20	1	686	1	718	2e-78	277
rs:WP_006717153	DNA topoisomerase III [Desulfitobacterium metallireducens].	31.65	654	394	19	3	627	5	634	2e-78	277
rs:WP_010786935	DNA topoisomerase III [Haemophilus parasuis].	30.92	621	388	16	1	589	1	612	2e-78	275
rs:WP_028393890	DNA topoisomerase III [Bacillus sp. FJAT-14515].	32.42	660	386	24	3	627	5	639	2e-78	277
rs:WP_033606645	DNA topoisomerase III [Enterococcus faecium].	30.40	658	398	17	2	644	3	615	2e-78	276
rs:WP_026581149	DNA topoisomerase III [Bacillus sp. J33].	29.99	727	437	21	1	676	1	706	2e-78	276
rs:WP_022426443	DNA topoisomerase [Ruminococcus sp. CAG:90].	31.22	663	392	18	3	627	4	640	2e-78	277
tr:B1BJK1_CLOPF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.37	658	388	21	2	627	3	635	2e-78	277
rs:WP_017553244	DNA topoisomerase III [Bacillus coagulans].	29.71	727	447	20	3	683	5	713	2e-78	276
rs:WP_020756607	DNA topoisomerase III [Geobacillus sp. WSUCF1].	28.59	717	469	19	1	681	1	710	2e-78	276
rs:WP_033607310	DNA topoisomerase III [Enterococcus faecium].	30.40	658	398	17	2	644	3	615	2e-78	276
rs:WP_014680744	DNA topoisomerase III [Solitalea canadensis].	30.21	715	440	17	1	676	1	695	2e-78	276
tr:E9RWM8_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.85	653	402	20	3	626	15	653	2e-78	277
rs:WP_039959342	DNA topoisomerase III [[Ruminococcus] gnavus].	29.04	699	441	19	2	671	5	677	2e-78	276
rs:WP_027603251	DNA topoisomerase III [Pseudomonas sp. LAMO17WK12:I2].	27.91	670	434	15	1	638	1	653	2e-78	275
tr:A0A0B5WW23_BACCO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.57	727	448	20	3	683	1	709	2e-78	276
rs:WP_043934594	DNA topoisomerase III [Bacillus sp. EB01].	28.75	654	423	14	3	646	4	624	2e-78	276
rs:WP_043052039	DNA topoisomerase [Streptococcus equi].	32.89	599	359	14	1	587	1	568	2e-78	273
rs:WP_025866525	DNA topoisomerase III [Bacteroides nordii].	32.07	633	372	17	1	592	1	616	2e-78	276
rs:WP_012621725	DNA topoisomerase III [Haemophilus parasuis].	31.19	622	385	18	1	589	1	612	2e-78	275
rs:WP_006255415	DNA topoisomerase I [Alloprevotella tannerae].	30.57	700	430	20	1	673	2	672	2e-78	276
rs:WP_032596729	DNA topoisomerase I [Bacteroides fragilis].	31.39	704	424	23	1	676	1	673	2e-78	276
rs:WP_035334438	MULTISPECIES: DNA topoisomerase III, partial [Bacillus].	30.75	709	422	23	2	679	3	673	2e-78	275
rs:WP_038643496	DNA topoisomerase III [Pantoea rwandensis].	29.38	674	430	14	1	641	1	661	2e-78	275
rs:WP_044297029	DNA topoisomerase III [Robinsoniella peoriensis].	31.65	654	399	21	3	627	4	638	2e-78	276
rs:WP_010302694	DNA topoisomerase III [Kurthia sp. JC8E].	32.08	667	376	26	4	627	6	638	2e-78	276
rs:WP_025845013	DNA topoisomerase III [Brevibacillus agri].	29.16	734	456	20	1	686	1	718	2e-78	276
rs:WP_017040350	DNA topoisomerase III [Vibrio genomosp. F10].	31.70	593	364	13	2	560	3	588	2e-78	275
rs:WP_026881876	DNA topoisomerase III [Clostridium akagii].	32.06	655	396	21	3	627	5	640	2e-78	276
rs:WP_010260636	MULTISPECIES: DNA topoisomerase III [Pantoea].	30.94	627	362	18	1	581	1	602	2e-78	274
tr:C3AGX8_BACMY	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	34.23	593	350	17	3	570	5	582	2e-78	273
rs:WP_036844649	DNA topoisomerase I [Porphyromonas sp. COT-108 OH1349].	29.96	701	440	20	1	676	1	675	2e-78	276
rs:WP_005712905	DNA topoisomerase III [Haemophilus parasuis].	31.86	612	377	17	1	581	1	603	2e-78	274
tr:A0A015X0P0_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EXZ04049.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EXZ04049.1};	30.43	700	376	22	28	629	13	699	2e-78	276
rs:WP_026893097	DNA topoisomerase III [[Clostridium] aerotolerans].	31.71	656	397	19	3	627	4	639	2e-78	276
rs:WP_007484229	DNA topoisomerase III [Bacteroides nordii].	32.07	633	372	17	1	592	1	616	2e-78	276
tr:A7AZM6_RUMGN	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.04	699	441	19	2	671	7	679	2e-78	276
rs:WP_028897449	DNA topoisomerase I [Prevotella sp. HUN102].	30.78	718	442	24	1	684	1	697	2e-78	276
rs:WP_021737651	DNA topoisomerase [Eubacterium ramulus].	31.44	652	401	19	3	627	5	637	2e-78	276
rs:WP_002306019	DNA topoisomerase III [Enterococcus faecium].	30.40	658	398	17	2	644	3	615	2e-78	276
rs:WP_033771944	DNA topoisomerase III [Pantoea agglomerans].	30.94	627	362	18	1	581	1	602	2e-78	274
rs:WP_010607879	DNA topoisomerase III [Pseudoalteromonas flavipulchra].	31.75	611	371	15	1	578	1	598	2e-78	274
rs:WP_013260124	DNA topoisomerase III [gamma proteobacterium HdN1].	30.69	655	392	19	1	605	1	643	2e-78	275
rs:WP_021427439	DNA topoisomerase III [Peptoclostridium difficile].	33.22	599	357	15	1	587	1	568	2e-78	272
rs:WP_042259147	DNA topoisomerase III [Clostridium perfringens].	32.37	658	388	21	2	627	6	638	2e-78	276
rs:WP_039431396	DNA topoisomerase I [Porphyromonas gulae].	29.96	701	440	20	1	676	1	675	2e-78	276
rs:WP_044932415	DNA topoisomerase III [Faecalitalea cylindroides].	30.04	699	445	16	1	676	1	678	2e-78	276
rs:WP_004091429	DNA topoisomerase [Xylella fastidiosa].	30.71	674	415	18	1	630	1	666	2e-78	275
rs:WP_017217778	DNA topoisomerase III [Pseudoalteromonas sp. NJ631].	31.75	611	371	15	1	578	1	598	2e-78	274
rs:WP_021311269	DNA topoisomerase III [Bacteroidetes bacterium oral taxon 272].	31.03	638	383	15	1	590	1	629	2e-78	276
rs:WP_042230926	DNA topoisomerase [Peptoniphilus senegalensis].	34.32	606	337	17	3	587	5	570	2e-78	272
rs:WP_024838128	DNA topoisomerase III [Clostridium sp. 12(A)].	31.71	656	397	19	3	627	4	639	2e-78	276
rs:WP_022383850	DNA topoisomerase III [Bacteroides sp. CAG:462].	30.38	711	402	22	1	629	1	700	2e-78	276
rs:WP_012587335	DNA topoisomerase III [Shewanella baltica].	30.54	645	383	15	1	591	1	634	2e-78	276
rs:WP_015592305	DNA topoisomerase III [Bacillus sp. 1NLA3E].	29.52	664	405	19	3	646	4	624	2e-78	276
rs:WP_036872634	DNA topoisomerase I [Porphyromonas macacae].	30.04	699	442	19	1	676	1	675	3e-78	275
rs:WP_026680417	DNA topoisomerase III [Bacillus megaterium].	31.00	629	404	17	3	615	5	619	3e-78	276
rs:WP_041997876	DNA topoisomerase III [Aeromonas bivalvium].	29.74	686	418	19	1	642	1	666	3e-78	275
rs:WP_025019241	DNA topoisomerase I [Bacteroides sartorii].	28.41	697	460	16	1	677	1	678	3e-78	275
rs:WP_002308233	DNA topoisomerase III [Enterococcus faecium].	30.29	657	400	17	2	644	3	615	3e-78	275
rs:WP_012146809	DNA topoisomerase III [Serratia proteamaculans].	29.32	607	397	10	1	581	1	601	3e-78	275
rs:WP_026887816	DNA topoisomerase III [Clostridium beijerinckii].	32.36	652	392	20	3	627	5	634	3e-78	276
rs:WP_008077959	DNA topoisomerase III [Vibrio sinaloensis].	31.05	612	383	13	2	581	3	607	3e-78	275
rs:WP_033655186	DNA topoisomerase III [Enterococcus faecium].	30.40	658	398	17	2	644	3	615	3e-78	275
rs:WP_019208345	DNA topoisomerase III [Phocaeicola abscessus].	31.51	641	376	16	1	590	1	629	3e-78	276
rs:WP_002570999	DNA topoisomerase III [[Clostridium] bolteae].	28.90	699	442	19	2	671	4	676	3e-78	275
rs:WP_033583050	DNA topoisomerase III [Enterococcus faecium].	30.40	658	398	17	2	644	3	615	3e-78	275
rs:WP_018915941	DNA topoisomerase III [Halomonas zhanjiangensis].	29.81	634	406	13	1	608	1	621	3e-78	274
rs:WP_006059585	DNA topoisomerase III [Holdemania filiformis].	29.00	700	442	19	1	671	1	674	3e-78	275
rs:WP_044742475	DNA topoisomerase III [Anoxybacillus sp. ATCC BAA-2555].	30.50	623	383	16	3	611	4	590	3e-78	275
rs:WP_000779854	DNA topoisomerase [Streptococcus agalactiae].	32.83	597	362	14	1	587	1	568	3e-78	272
rs:WP_000539255	DNA topoisomerase III [Bacillus cereus].	30.95	714	430	21	3	673	5	698	3e-78	276
rs:WP_042017937	DNA topoisomerase III [Aeromonas sobria].	31.24	621	392	14	1	593	1	614	3e-78	275
tr:U7UNB0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.34	594	339	16	3	580	29	587	3e-78	273
tr:R8CJY7_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.52	725	441	20	3	680	4	705	3e-78	276
rs:WP_024028720	DNA topoisomerase III [Bacillus vireti].	30.38	734	431	24	1	679	1	709	3e-78	276
rs:WP_037574799	DNA topoisomerase III [Staphylococcus chromogenes].	32.06	627	390	16	3	615	4	608	3e-78	276
tr:U3A8G4_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.82	662	405	18	1	630	1	641	3e-78	276
rs:WP_024893846	DNA topoisomerase III [Acidithiobacillus thiooxidans].	32.12	604	360	15	1	565	1	593	3e-78	275
rs:WP_042678050	DNA topoisomerase III [Pantoea sp. B40].	28.82	680	432	16	1	645	1	663	3e-78	275
rs:WP_021109548	DNA topoisomerase III [Haemophilus parasuis].	31.14	623	389	17	1	592	1	614	3e-78	274
rs:WP_024108348	DNA topoisomerase III [Dickeya dianthicola].	28.75	647	417	13	1	618	1	632	3e-78	275
rs:WP_014262114	DNA topoisomerase III [Filifactor alocis].	34.48	583	337	15	2	571	4	554	3e-78	272
rs:WP_021434765	DNA topoisomerase III family protein [Peptoclostridium difficile].	32.89	599	359	14	1	587	1	568	3e-78	272
rs:WP_004611672	hypothetical protein [Tyzzerella nexilis].	29.00	707	441	23	1	676	1	677	3e-78	275
rs:WP_032841868	DNA topoisomerase I [Bacteroides sp. 1_1_30].	28.90	699	453	19	1	677	1	677	3e-78	275
rs:WP_044807771	DNA topoisomerase III [Escherichia coli].	30.02	643	398	16	1	610	1	624	3e-78	275
rs:WP_016439735	DNA topoisomerase III [Coprococcus sp. HPP0074].	31.70	653	403	20	3	626	4	642	3e-78	276
rs:WP_033563343	DNA topoisomerase I [Sphingobacteriaceae bacterium DW12].	31.22	711	440	19	1	676	1	697	3e-78	275
rs:WP_014824222	DNA topoisomerase III [Solibacillus silvestris].	29.24	725	461	18	1	682	1	716	3e-78	276
rs:WP_009568422	DNA topoisomerase III family protein [Streptococcus intermedius].	33.72	599	354	15	1	587	1	568	4e-78	272
rs:WP_018716119	DNA topoisomerase III [Brachymonas chironomi].	29.08	736	446	23	3	680	5	722	4e-78	280
rs:WP_035685029	DNA topoisomerase III [Avibacterium paragallinarum].	31.25	640	391	18	1	605	1	626	4e-78	274
rs:WP_039588664	DNA topoisomerase III [Pseudomonas frederiksbergensis].	27.76	670	435	15	1	638	1	653	4e-78	274
rs:WP_002997248	transposase [Sphingobacterium spiritivorum].	30.66	711	444	18	1	676	1	697	4e-78	275
rs:WP_013052140	DNA topoisomerase III [Shewanella violacea].	30.95	643	394	14	1	601	1	635	4e-78	274
tr:F3J716_PSEAP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.30	710	435	18	1	659	1	694	4e-78	275
rs:WP_002592896	DNA topoisomerase III [[Clostridium] clostridioforme].	29.47	699	436	20	2	670	5	676	4e-78	275
rs:WP_021259547	DNA topoisomerase III [Paenibacillus alvei].	30.46	696	411	22	3	666	4	658	4e-78	275
rs:WP_039011295	DNA topoisomerase III [Pseudomonas brassicacearum].	27.79	673	431	15	1	638	1	653	4e-78	274
rs:WP_021114992	DNA topoisomerase III [Haemophilus parasuis].	30.76	621	388	17	1	589	1	611	4e-78	274
rs:WP_006085455	DNA topoisomerase III [Shewanella baltica].	30.54	645	383	15	1	591	1	634	4e-78	275
rs:WP_033016990	DNA topoisomerase III [Geobacillus stearothermophilus].	29.13	721	460	21	1	681	1	710	4e-78	275
rs:WP_034875432	DNA topoisomerase III [Endozoicomonas montiporae].	31.72	618	379	17	1	581	1	612	4e-78	274
rs:WP_028899761	DNA topoisomerase I [Prevotella sp. HJM029].	30.18	709	436	23	1	677	1	682	4e-78	275
rs:WP_032629416	DNA topoisomerase III [Pseudomonas syringae].	29.67	664	413	18	1	629	1	645	4e-78	274
tr:A0A0E2SUF0_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EXZ76979.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EXZ76979.1};	30.43	700	376	22	28	629	13	699	4e-78	275
rs:WP_014610819	DNA topoisomerase III [Shewanella putrefaciens].	30.55	658	396	15	1	606	1	649	4e-78	275
rs:WP_023397678	DNA topoisomerase III [Pseudoalteromonas luteoviolacea].	32.58	620	379	15	1	588	1	613	4e-78	274
rs:WP_040531935	DNA topoisomerase III, partial [Lautropia mirabilis].	30.07	715	429	21	3	673	5	692	4e-78	278
rs:WP_002577979	DNA topoisomerase III [[Clostridium] bolteae].	28.98	697	443	18	2	671	4	675	4e-78	275
rs:WP_028068979	DNA topoisomerase I [Sphingobacterium thalpophilum].	31.03	709	424	23	1	676	1	677	4e-78	275
rs:WP_036059528	hypothetical protein [Listeria weihenstephanensis].	29.49	712	436	19	1	683	1	675	4e-78	275
rs:WP_002340557	DNA topoisomerase III [Enterococcus faecium].	30.91	728	433	25	1	675	2	712	4e-78	275
rs:WP_019120897	DNA topoisomerase III [Brevibacillus massiliensis].	32.63	662	382	23	3	627	5	639	4e-78	276
rs:WP_004308419	MULTISPECIES: DNA topoisomerase I [Bacteroides].	30.16	703	441	22	1	676	1	680	4e-78	275
rs:WP_021804264	DNA topoisomerase III [Clostridium intestinale].	30.97	636	396	17	3	615	5	620	4e-78	276
rs:WP_002432733	DNA topoisomerase III [Staphylococcus capitis].	31.55	634	384	14	3	615	4	608	4e-78	275
gp:CP005384_686	DNA topoisomerase III [Haemophilus parasuis ZJ0906]	31.14	623	389	17	1	592	1	614	4e-78	273
rs:WP_005642341	DNA topoisomerase I [Parabacteroides merdae].	29.72	710	445	21	1	684	1	682	4e-78	275
rs:WP_033585993	DNA topoisomerase III [Enterococcus faecium].	30.40	658	398	17	2	644	3	615	4e-78	275
rs:WP_016807975	DNA topoisomerase III [Klebsiella oxytoca].	29.42	639	405	14	1	610	1	622	5e-78	274
rs:WP_027294681	DNA topoisomerase III [Robinsoniella sp. KNHs210].	31.44	652	403	19	3	627	4	638	5e-78	276
tr:A0A0D3LDW1_9BACT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AHM60286.1};	29.12	728	451	19	1	678	1	713	5e-78	275
rs:WP_004083178	DNA topoisomerase III [Clostridium sp. ASF502].	29.82	721	441	22	1	687	1	690	5e-78	275
rs:WP_046148757	DNA topoisomerase I [Parabacteroides sp. HGS0025].	29.56	707	452	17	1	682	1	686	5e-78	275
rs:WP_003426113	DNA topoisomerase III [Peptoclostridium difficile].	33.22	599	357	15	1	587	1	568	5e-78	271
rs:WP_037430092	DNA topoisomerase III [Shewanella sp. POL2].	31.06	644	364	15	1	581	1	627	5e-78	275
rs:WP_025218532	DNA topoisomerase III [Lysinibacillus varians].	32.73	660	384	23	3	627	5	639	5e-78	276
rs:WP_005643615	DNA topoisomerase I [Parabacteroides merdae].	29.08	698	445	21	1	673	1	673	5e-78	275
rs:WP_015389938	DNA topoisomerase III [Kinetoplastibacterium blastocrithidii].	31.44	738	409	29	2	680	4	703	5e-78	277
rs:WP_012325583	DNA topoisomerase III [Shewanella woodyi].	30.03	646	401	14	1	602	1	639	5e-78	274
rs:WP_018355342	DNA topoisomerase III [Pasteurella pneumotropica].	32.48	622	368	19	1	581	1	611	5e-78	273
rs:WP_005705826	DNA topoisomerase III [Haemophilus parahaemolyticus].	32.45	607	366	15	1	574	1	596	5e-78	273
rs:WP_039338988	DNA topoisomerase III [Pantoea stewartii].	28.48	660	428	13	1	629	1	647	5e-78	274
rs:WP_001562956	DNA topoisomerase III [Escherichia coli].	29.53	684	416	19	1	641	1	661	5e-78	274
rs:WP_021393351	DNA topoisomerase III [Peptoclostridium difficile].	33.79	586	345	15	1	574	1	555	5e-78	271
rs:WP_005678837	DNA topoisomerase III [Bacteroides caccae].	31.09	624	385	14	1	588	1	615	5e-78	275
rs:WP_029506177	DNA topoisomerase III, partial [Lachnospiraceae bacterium AC2012].	31.40	621	366	17	1	585	1	597	5e-78	273
tr:A0A073IBB1_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KEJ86811.1};	29.29	700	443	20	4	677	5	678	5e-78	275
tr:A5ZNQ6_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.55	639	377	20	70	679	1	614	5e-78	273
rs:WP_010318864	DNA topoisomerase III [Vibrio ordalii].	31.48	613	379	16	2	581	3	607	5e-78	273
rs:WP_013859245	DNA topoisomerase III [Bacillus coagulans].	29.57	727	448	20	3	683	5	713	5e-78	275
rs:WP_044168813	DNA topoisomerase I [Porphyromonas catoniae].	30.63	702	420	22	4	673	5	671	5e-78	275
rs:WP_027849899	DNA topoisomerase III [Marinospirillum insulare].	31.51	622	370	18	1	581	1	607	5e-78	273
rs:WP_038991132	DNA topoisomerase III [Klebsiella pneumoniae].	29.58	639	404	14	1	610	1	622	5e-78	274
rs:WP_043082055	DNA topoisomerase III [Pluralibacter gergoviae].	29.42	639	405	14	1	610	1	622	5e-78	274
rs:WP_035066549	DNA topoisomerase III [Anoxybacillus gonensis].	29.92	665	398	19	3	646	4	621	5e-78	275
rs:WP_007524702	DNA topoisomerase III [Haemophilus sputorum].	31.38	615	376	19	1	581	1	603	5e-78	273
rs:WP_013521814	DNA topoisomerase III [Taylorella equigenitalis].	31.28	732	414	26	3	680	5	701	5e-78	277
rs:WP_039151066	DNA topoisomerase III [Gallibacterium anatis].	31.26	627	370	17	1	581	1	612	5e-78	273
tr:D4LMY3_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.37	663	391	18	3	627	4	640	5e-78	275
rs:WP_032567764	DNA topoisomerase I [Bacteroides fragilis].	30.80	711	434	24	1	684	1	680	5e-78	275
rs:WP_002561265	DNA topoisomerase III [Bacteroides sp. HPS0048].	29.56	707	452	17	1	682	1	686	5e-78	275
rs:WP_019442553	DNA topoisomerase III [Moritella marina].	31.61	620	375	17	1	582	1	609	6e-78	273
tr:D7INW6_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFI09104.1};	28.73	703	455	15	1	678	1	682	6e-78	275
rs:WP_022042877	DNA topoisomerase III [Bacteroides caccae CAG:21].	31.09	624	385	14	1	588	1	615	6e-78	275
rs:WP_021422759	DNA topoisomerase III family protein [Peptoclostridium difficile].	32.89	599	359	14	1	587	1	568	6e-78	271
rs:WP_017099216	DNA topoisomerase III [Vibrio tasmaniensis].	31.00	613	384	12	2	581	3	609	6e-78	273
rs:WP_021112325	DNA topoisomerase III [Haemophilus parasuis].	30.61	624	391	17	1	592	1	614	6e-78	273
rs:WP_039492215	DNA topoisomerase III [Pseudoalteromonas elyakovii].	31.75	611	371	15	1	578	1	598	6e-78	273
rs:WP_023182587	DNA topoisomerase III [Salmonella enterica].	31.03	609	383	14	1	587	1	594	6e-78	272
rs:WP_013752942	DNA topoisomerase III [Glaciecola sp. 4H-3-7+YE-5].	30.56	612	386	12	1	581	1	604	6e-78	273
rs:WP_012603511	DNA topoisomerase III [Vibrio tasmaniensis].	31.00	613	384	12	2	581	3	609	6e-78	274
rs:WP_011231305	DNA topoisomerase III [Geobacillus kaustophilus].	28.99	721	461	21	1	681	1	710	6e-78	275
rs:WP_042596196	DNA topoisomerase III [Bacillus thuringiensis].	30.81	714	431	21	3	673	5	698	6e-78	275
rs:WP_033627655	DNA topoisomerase III [Enterococcus faecium].	30.44	657	399	16	2	644	3	615	6e-78	274
rs:WP_005656475	DNA topoisomerase III [Haemophilus influenzae].	31.41	624	376	18	1	583	1	613	6e-78	273
rs:WP_038913061	DNA topoisomerase III [Dickeya zeae].	29.06	647	415	13	1	618	1	632	6e-78	274
rs:WP_046099940	DNA topoisomerase III [Staphylococcus carnosus].	32.23	636	376	17	3	615	4	607	6e-78	275
tr:I1E068_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.24	694	420	14	1	644	1	666	6e-78	274
rs:WP_026624798	DNA topoisomerase III [Eggerthia catenaformis].	33.44	601	351	15	3	588	4	570	6e-78	271
rs:WP_038133918	DNA topoisomerase III [Vibrio caribbeanicus].	32.15	591	362	14	2	560	3	586	7e-78	273
rs:WP_041635735	DNA topoisomerase III [Acidithiobacillus caldus].	29.77	665	422	15	1	640	1	645	7e-78	274
rs:WP_028762193	DNA topoisomerase III [Shewanella colwelliana].	30.58	677	415	20	1	638	1	661	7e-78	273
rs:WP_033606890	DNA topoisomerase III [Enterococcus faecium].	30.24	658	399	17	2	644	3	615	7e-78	274
rs:WP_002453790	DNA topoisomerase III [Staphylococcus capitis].	31.55	634	384	15	3	615	4	608	7e-78	275
tr:A0A017NAF6_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EYE44609.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EYE44609.1};	30.43	700	376	22	28	629	13	699	7e-78	275
tr:A0A078BN72_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.64	660	436	14	1	640	1	645	7e-78	275
rs:WP_021461897	DNA topoisomerase III [Gallibacterium anatis].	30.30	627	376	16	1	581	1	612	7e-78	273
rs:WP_016441614	DNA topoisomerase III [Coprococcus sp. HPP0048].	31.85	653	402	20	3	626	4	642	7e-78	275
rs:WP_012340838	MULTISPECIES: DNA topoisomerase III [Pasteurellaceae].	28.82	642	415	13	1	614	1	628	7e-78	274
rs:WP_005682722	DNA topoisomerase III [Bacteroides caccae].	31.09	624	385	14	1	588	1	615	7e-78	275
rs:WP_028761026	DNA topoisomerase III [Shewanella putrefaciens].	30.45	660	394	16	1	606	1	649	7e-78	275
rs:WP_021666176	DNA topoisomerase [Porphyromonas sp. oral taxon 278].	30.71	700	422	22	4	673	5	671	7e-78	274
rs:WP_022035697	DNA topoisomerase III [Roseburia sp. CAG:50].	31.29	652	402	19	3	627	5	637	7e-78	275
rs:WP_035519301	DNA topoisomerase III [Haemophilus parasuis].	31.00	613	381	17	1	581	1	603	7e-78	273
rs:WP_040883102	DNA topoisomerase [Johnsonella ignava].	34.01	588	333	16	4	571	1	553	7e-78	271
rs:WP_005921736	DNA topoisomerase III [Faecalibacterium prausnitzii].	29.54	677	414	19	29	671	11	658	8e-78	274
rs:WP_045984985	DNA topoisomerase III [Vibrio coralliilyticus].	31.21	612	382	13	2	581	3	607	8e-78	273
tr:E2SL06_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.05	661	420	17	1	638	1	635	8e-78	273
gpu:CP007601_1368	DNA topoisomerase 3 [Staphylococcus capitis subsp. capitis]	31.55	634	384	15	3	615	4	608	8e-78	275
rs:WP_005227252	DNA topoisomerase III [Enterococcus casseliflavus].	30.41	628	377	16	2	614	3	585	8e-78	274
rs:WP_044022747	DNA topoisomerase III [Bacillus sp. SG-1].	31.24	653	403	19	3	627	5	639	8e-78	275
rs:WP_011861365	DNA topoisomerase [Peptoclostridium difficile].	32.89	599	359	15	1	587	1	568	8e-78	271
tr:H7CWN7_CLOPF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.78	659	384	22	2	627	3	635	8e-78	275
rs:WP_025487928	DNA topoisomerase III [Clostridiales bacterium VE202-27].	29.04	699	443	18	1	671	1	674	8e-78	274
rs:WP_040883080	DNA topoisomerase [Johnsonella ignava].	33.62	589	346	16	5	580	1	557	8e-78	271
tr:C5ER81_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.23	698	441	19	2	671	4	676	8e-78	274
rs:WP_036658025	DNA topoisomerase III [Paenibacillus larvae].	31.04	670	399	21	3	646	4	636	8e-78	275
rs:WP_017797775	DNA topoisomerase III [Oceanobacillus kimchii].	31.79	648	395	19	3	626	5	629	8e-78	275
rs:WP_022345006	DNA topoisomerase [Clostridium sp. CAG:299].	30.22	685	392	19	3	627	4	662	8e-78	275
rs:WP_039811820	DNA topoisomerase III [Jeotgalibacillus sp. D5].	32.41	648	390	19	3	627	5	627	8e-78	275
rs:WP_040381961	DNA topoisomerase III [Clostridiales bacterium 1_7_47FAA].	29.23	698	441	19	2	671	5	677	9e-78	274
rs:WP_035379522	DNA topoisomerase III, partial [Fervidicella metallireducens].	32.07	605	362	15	3	581	5	586	9e-78	271
rs:WP_005577855	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	31.84	625	368	18	1	581	1	611	9e-78	273
rs:WP_021454915	DNA topoisomerase III [Vibrio coralliilyticus].	31.05	612	383	13	2	581	3	607	9e-78	273
rs:WP_003144959	DNA topoisomerase III [Gemella haemolysans].	30.86	648	406	16	3	638	4	621	9e-78	274
rs:WP_027847842	DNA topoisomerase III [Marinospirillum minutulum].	31.09	624	370	18	1	581	1	607	9e-78	273
rs:WP_037549984	DNA topoisomerase III [Staphylococcus sp. TE8].	31.55	634	384	15	3	615	4	608	9e-78	274
rs:WP_024551116	MULTISPECIES: DNA topoisomerase III [Cronobacter].	31.11	614	378	18	1	581	1	602	9e-78	273
rs:WP_044115448	DNA topoisomerase I [Porphyromonas sp. KLE 1280].	30.43	700	424	22	4	673	5	671	9e-78	274
rs:WP_010835677	DNA topoisomerase III [Salmonella enterica].	29.77	608	392	12	1	581	1	600	9e-78	273
rs:WP_005644270	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	28.73	703	455	16	1	678	24	705	9e-78	275
rs:WP_032566369	DNA topoisomerase I [Bacteroides fragilis].	30.42	710	447	21	1	684	1	689	9e-78	274
rs:WP_009263044	DNA topoisomerase III [Lachnospiraceae bacterium 9_1_43BFAA].	31.70	653	403	20	3	626	4	642	9e-78	275
rs:WP_040976203	DNA topoisomerase III [Pasteurella sp. FF6].	32.58	620	364	20	1	581	1	605	9e-78	273
tr:E7RZM8_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.07	715	429	21	3	673	5	692	9e-78	278
rs:WP_017063444	DNA topoisomerase III [Vibrio crassostreae].	31.42	592	367	12	2	560	3	588	9e-78	273
rs:WP_039482952	DNA topoisomerase III [Vibrio sinaloensis].	32.15	591	362	14	2	560	3	586	1e-77	273
rs:WP_038653193	DNA topoisomerase I [Mucinivorans hirudinis].	29.73	703	441	19	1	676	1	677	1e-77	274
rs:WP_025844431	DNA topoisomerase III [Paenibacillus ehimensis].	29.67	718	407	21	3	667	4	676	1e-77	274
rs:WP_034692209	DNA topoisomerase I [Chryseobacterium sp. CF365].	32.34	705	419	23	1	673	1	679	1e-77	274
rs:WP_009332651	DNA topoisomerase III [Bacillus sp. 2_A_57_CT2].	30.99	739	426	24	1	682	1	712	1e-77	275
rs:WP_021771516	DNA topoisomerase [Mitsuokella sp. oral taxon 131].	29.22	705	443	20	1	664	1	690	1e-77	277
rs:WP_034824013	DNA topoisomerase III [Clostridium perfringens].	32.78	659	384	22	2	627	6	638	1e-77	275
rs:WP_032080988	DNA topoisomerase III [Vibrio fluvialis].	30.53	619	377	13	2	581	3	607	1e-77	273
rs:WP_039677235	DNA topoisomerase [Streptococcus constellatus].	34.14	577	335	15	1	564	1	545	1e-77	271
rs:WP_035493689	DNA topoisomerase III [Haemophilus parasuis].	30.76	621	388	17	1	589	1	611	1e-77	273
gpu:CP011832_1725	DNA topoisomerase 3 [Geobacillus sp. 12AMOR1]	28.83	718	466	20	1	681	1	710	1e-77	274
rs:WP_023405646	DNA topoisomerase III [Vibrio halioticoli].	31.05	612	364	18	2	571	3	598	1e-77	273
rs:WP_019686166	DNA topoisomerase III [Paenibacillus polymyxa].	29.96	681	394	21	3	646	4	638	1e-77	274
rs:WP_002589130	DNA topoisomerase III [[Clostridium] clostridioforme].	29.12	704	446	19	1	676	1	679	1e-77	274
rs:WP_002559428	DNA topoisomerase III [Bacteroides sp. HPS0048].	31.91	633	373	17	1	592	1	616	1e-77	275
rs:WP_047199997	DNA topoisomerase [Streptococcus agalactiae].	33.61	598	356	14	1	587	1	568	1e-77	271
rs:WP_028298222	DNA topoisomerase III [Olivibacter sitiensis].	29.49	702	431	22	1	661	1	679	1e-77	274
rs:WP_008880142	MULTISPECIES: DNA topoisomerase III [Geobacillus].	28.73	717	468	20	1	681	1	710	1e-77	274
tr:W0QQA8_9PAST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.66	642	416	13	1	614	20	647	1e-77	274
rs:WP_020432484	DNA topoisomerase III [Vibrio fluvialis].	30.69	619	376	13	2	581	3	607	1e-77	273
rs:WP_019416613	DNA topoisomerase III [Anoxybacillus kamchatkensis].	30.08	665	397	19	3	646	4	621	1e-77	274
rs:WP_017066255	DNA topoisomerase III [Vibrio crassostreae].	31.42	592	367	12	2	560	3	588	1e-77	273
rs:WP_033843831	DNA topoisomerase III [Geobacillus subterraneus].	28.73	717	468	20	1	681	1	710	1e-77	274
rs:WP_010899528	DNA topoisomerase III [Bacillus halodurans].	29.97	714	460	16	3	681	5	713	1e-77	274
rs:WP_017089851	DNA topoisomerase III [Vibrio splendidus].	31.59	592	366	12	2	560	3	588	1e-77	273
rs:WP_039989635	DNA topoisomerase III, partial [Glaciecola arctica].	29.25	636	371	18	1	581	1	612	1e-77	272
rs:WP_008303213	DNA topoisomerase III [Glaciecola agarilytica].	30.77	611	386	11	1	581	1	604	1e-77	272
rs:WP_017070329	DNA topoisomerase III [Vibrio crassostreae].	31.42	592	367	12	2	560	3	588	1e-77	273
rs:WP_032581436	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	29.16	703	446	20	1	677	1	677	1e-77	274
rs:WP_004734086	DNA topoisomerase III [Vibrio splendidus].	31.59	592	366	12	2	560	3	588	1e-77	273
rs:WP_009131566	DNA topoisomerase III [Bacteroides oleiciplenus].	30.08	728	433	22	3	684	6	703	1e-77	274
rs:WP_031575408	DNA topoisomerase III, partial [Acidithiobacillus thiooxidans].	30.26	608	385	16	1	581	1	596	1e-77	273
tr:J8GVI6_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.95	714	430	21	3	673	79	772	1e-77	276
rs:WP_038323548	DNA topoisomerase III [bacterium MS4].	28.29	654	419	16	1	638	1	620	1e-77	273
rs:WP_017084055	DNA topoisomerase III [Vibrio splendidus].	31.59	592	366	12	2	560	3	588	1e-77	273
rs:WP_007901001	DNA topoisomerase III [Pseudomonas sp. GM102].	28.18	660	425	16	1	629	1	642	1e-77	273
rs:WP_009662899	DNA topoisomerase III [Lachnoanaerobaculum sp. ICM7].	33.45	589	341	15	1	571	1	556	1e-77	271
rs:WP_008396945	DNA topoisomerase III [Clostridium sp. M62/1].	30.16	673	404	18	3	627	4	658	1e-77	275
rs:WP_006522960	DNA topoisomerase III [Desulfotomaculum gibsoniae].	30.84	655	403	20	3	627	5	639	1e-77	275
rs:WP_012315136	MULTISPECIES: DNA topoisomerase III [Pseudomonas putida group].	27.61	670	438	14	1	640	1	653	1e-77	273
rs:WP_046222677	DNA topoisomerase III [Vibrio sp. ECSMB14106].	31.42	592	367	12	2	560	3	588	1e-77	273
rs:WP_041028003	DNA topoisomerase III, partial [Salmonella enterica].	32.69	569	340	19	1	537	1	558	1e-77	270
rs:WP_013523745	MULTISPECIES: DNA topoisomerase III [Geobacillus].	29.85	660	408	17	3	646	4	624	1e-77	274
rs:WP_005473440	DNA topoisomerase III [Vibrio sp. 16].	32.15	591	362	14	2	560	3	586	1e-77	273
rs:WP_008780590	DNA topoisomerase I [Bacteroides sp. 3_1_19].	30.16	703	441	22	1	676	1	680	1e-77	274
rs:WP_004798049	DNA topoisomerase III [[Eubacterium] dolichum].	29.33	699	439	20	2	671	5	677	1e-77	274
rs:WP_026648425	DNA topoisomerase III [Blautia wexlerae].	31.05	657	404	18	3	627	4	643	1e-77	275
rs:WP_038191560	DNA topoisomerase III [Vibrio sinaloensis].	31.77	598	355	15	2	560	3	586	1e-77	273
rs:WP_039475777	DNA topoisomerase III [Vibrio sinaloensis].	31.93	592	362	14	2	560	3	586	1e-77	273
rs:WP_031409354	DNA topoisomerase III [Geobacillus vulcani].	28.45	717	470	20	1	681	1	710	1e-77	274
rs:WP_043955306	DNA topoisomerase III [Enterobacter sp. YD4].	29.93	608	393	13	1	585	1	598	1e-77	271
rs:WP_043037586	DNA topoisomerase, partial [Streptococcus equi].	34.12	595	325	18	1	571	1	552	1e-77	270
rs:WP_017092500	DNA topoisomerase III [Vibrio splendidus].	31.59	592	366	12	2	560	3	588	1e-77	273
rs:WP_024566104	DNA topoisomerase I, partial [Elizabethkingia anophelis].	31.43	700	433	22	1	676	1	677	1e-77	273
rs:WP_017059374	DNA topoisomerase III [Vibrio crassostreae].	31.42	592	367	12	2	560	3	588	1e-77	273
rs:WP_023169111	DNA topoisomerase III, partial [Salmonella enterica].	31.50	600	372	18	41	608	2	594	1e-77	271
rs:WP_038855881	DNA topoisomerase III [Pseudomonas fluorescens].	28.16	657	430	16	1	632	1	640	1e-77	273
rs:WP_029503852	DNA topoisomerase III [Lachnoclostridium phytofermentans].	32.07	661	381	23	3	627	4	632	1e-77	274
rs:WP_007784264	DNA topoisomerase III [Brevibacillus sp. CF112].	29.06	733	458	19	1	686	1	718	1e-77	274
rs:WP_017080912	DNA topoisomerase III [Vibrio splendidus].	31.59	592	366	12	2	560	3	588	1e-77	273
rs:WP_026909310	DNA topoisomerase III [Paucisalibacillus globulus].	30.06	632	406	15	3	615	5	619	1e-77	274
rs:WP_045151977	DNA topoisomerase III [Photobacterium angustum].	32.13	607	367	16	2	574	3	598	1e-77	273
tr:F7M0K7_9BACE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGN09098.1};	28.88	696	451	19	4	677	5	678	1e-77	274
rs:WP_004360034	DNA topoisomerase I [Prevotella melaninogenica].	30.63	702	427	22	1	673	2	672	1e-77	273
rs:WP_038213471	DNA topoisomerase III [Vibrio variabilis].	31.93	595	358	15	2	560	3	586	1e-77	273
rs:WP_026672191	DNA topoisomerase III [Bacillus bogoriensis].	31.33	648	408	17	3	627	5	638	1e-77	274
rs:WP_006058367	DNA topoisomerase III [Holdemania filiformis].	29.94	718	437	20	2	680	3	693	1e-77	273
rs:WP_045525843	DNA topoisomerase III [Aeromonas hydrophila].	29.91	652	414	16	1	624	1	637	1e-77	273
rs:WP_009461407	DNA topoisomerase III [Lachnospiraceae bacterium 2_1_46FAA].	32.00	650	398	19	3	627	4	634	1e-77	274
rs:WP_026559271	DNA topoisomerase III [Bacillus sp. J37].	30.80	711	423	23	1	662	1	691	1e-77	274
rs:WP_019379736	DNA topoisomerase III [Bacillus oceanisediminis].	30.99	739	426	24	1	682	1	712	1e-77	274
rs:WP_028532117	DNA topoisomerase III [Paenibacillus sp. UNC217MF].	30.58	641	384	17	3	615	4	611	1e-77	274
rs:WP_017038719	DNA topoisomerase III [Vibrio genomosp. F10].	31.53	593	365	13	2	560	3	588	1e-77	273
rs:WP_045127804	DNA topoisomerase III [Photobacterium angustum].	32.13	607	367	16	2	574	3	598	1e-77	273
rs:WP_002339105	DNA topoisomerase III [Enterococcus faecium].	30.24	658	399	17	2	644	3	615	1e-77	273
rs:WP_019615207	DNA topoisomerase III [Psychromonas ossibalaenae].	31.77	620	366	15	1	581	1	602	1e-77	272
rs:WP_038695639	DNA topoisomerase I [Sphingobacterium sp. ML3W].	30.52	711	444	21	1	676	1	696	2e-77	273
rs:WP_045083314	MULTISPECIES: DNA topoisomerase III [Photobacterium].	32.38	593	356	16	2	560	3	584	2e-77	273
rs:WP_041847283	DNA topoisomerase III [Bacillus thermoamylovorans].	30.93	721	442	20	3	681	5	711	2e-77	274
rs:WP_018589388	DNA topoisomerase III [Terrisporobacter glycolicus].	32.11	654	380	21	3	631	5	619	2e-77	273
rs:WP_033651462	DNA topoisomerase III [Enterococcus faecium].	30.24	658	399	17	2	644	3	615	2e-77	273
rs:WP_029466987	DNA topoisomerase III [[Clostridium] hathewayi].	29.18	699	442	18	1	671	1	674	2e-77	273
rs:WP_011544434	TraE DNA topoisomerase [uncultured bacterium].	28.91	716	447	18	1	671	1	699	2e-77	274
rs:WP_037328208	DNA topoisomerase [Anaerococcus lactolyticus].	32.50	600	358	13	3	588	5	571	2e-77	270
tr:A8MG43_ALKOO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.03	637	392	17	2	615	15	633	2e-77	274
rs:WP_025194606	DNA topoisomerase III [Streptococcus agalactiae].	34.62	598	332	16	3	580	5	563	2e-77	270
rs:WP_040663200	DNA topoisomerase III [Oscillibacter ruminantium].	28.73	703	447	19	1	682	1	670	2e-77	273
rs:WP_033652941	DNA topoisomerase III [Enterococcus faecium].	30.24	658	399	17	2	644	3	615	2e-77	273
rs:WP_041719022	DNA topoisomerase III [Alkaliphilus oremlandii].	32.03	637	392	17	2	615	4	622	2e-77	274
rs:WP_021254751	DNA topoisomerase III [Paenibacillus alvei].	30.58	641	384	17	3	615	4	611	2e-77	274
rs:WP_017099417	DNA topoisomerase III [Vibrio tasmaniensis].	31.59	592	366	12	2	560	3	588	2e-77	272
rs:WP_007045777	DNA topoisomerase III [Subdoligranulum variabile].	28.90	699	442	19	2	671	5	677	2e-77	273
tr:B1BWJ0_CLOPF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.37	658	388	21	2	627	3	635	2e-77	274
rs:WP_029706781	DNA topoisomerase III [Rhodoferax saidenbachensis].	30.70	746	425	27	3	680	4	725	2e-77	278
rs:WP_011788910	DNA topoisomerase III [Shewanella sp. W3-18-1].	30.79	643	384	15	1	591	1	634	2e-77	273
rs:WP_032572846	DNA topoisomerase I [Bacteroides fragilis].	31.25	704	425	23	1	676	1	673	2e-77	273
rs:WP_002313368	DNA topoisomerase III [Enterococcus faecium].	30.14	657	401	17	2	644	3	615	2e-77	273
rs:WP_002569206	DNA topoisomerase III [[Clostridium] bolteae].	29.04	699	443	18	1	671	1	674	2e-77	273
rs:WP_038925525	DNA topoisomerase III [Dickeya zeae].	28.90	647	416	13	1	618	1	632	2e-77	273
rs:WP_031594540	DNA topoisomerase III [Pantoea agglomerans].	29.42	639	405	14	1	610	1	622	2e-77	273
rs:WP_011919518	DNA topoisomerase III [Shewanella putrefaciens].	30.79	643	384	15	1	591	1	634	2e-77	273
rs:WP_021388935	DNA topoisomerase, partial [Peptoclostridium difficile].	33.21	548	325	14	1	528	1	527	2e-77	269
rs:WP_017033131	DNA topoisomerase III [Vibrio genomosp. F10].	31.37	593	366	13	2	560	3	588	2e-77	273
rs:WP_043013202	DNA topoisomerase III [Clostridium perfringens].	32.37	658	388	21	2	627	6	638	2e-77	274
rs:WP_042530086	DNA topoisomerase III [Oceanobacillus oncorhynchi].	30.71	648	405	18	3	626	5	632	2e-77	274
rs:WP_034675203	DNA topoisomerase I [Chryseobacterium formosense].	31.67	723	431	22	1	683	1	700	2e-77	273
rs:WP_027852468	DNA topoisomerase III [Marinobacterium litorale].	31.12	617	370	17	1	581	1	598	2e-77	272
rs:WP_009848706	DNA topoisomerase III [Vibrio sp. MED222].	30.67	613	386	12	2	581	3	609	2e-77	272
tr:K6Z8H7_9ALTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.25	636	371	18	1	581	1	612	2e-77	272
rs:WP_014078553	DNA topoisomerase III [Roseburia hominis].	29.04	699	441	19	2	671	5	677	2e-77	273
tr:D6DE15_CLOSC	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.97	674	405	18	3	627	4	659	2e-77	275
rs:WP_042371906	DNA topoisomerase I [Bacteroidaceae bacterium MS4].	30.77	715	432	24	1	684	1	683	2e-77	273
rs:WP_033624242	DNA topoisomerase III [Enterococcus faecium].	30.24	658	399	17	2	644	3	615	2e-77	273
rs:WP_025068261	DNA topoisomerase I [Prevotella denticola].	30.97	704	422	23	1	673	2	672	2e-77	273
rs:WP_032938611	DNA topoisomerase I [Bacteroides vulgatus].	29.18	699	451	19	1	677	1	677	2e-77	273
rs:WP_004414842	DNA topoisomerase III [Vibrio orientalis].	32.27	595	356	14	2	560	3	586	2e-77	272
rs:WP_004740668	DNA topoisomerase III [Vibrio splendidus].	31.08	592	369	11	2	560	3	588	2e-77	272
rs:WP_019035128	DNA topoisomerase III [Peptoniphilus lacrimalis].	33.44	604	335	19	1	580	1	561	2e-77	270
rs:WP_039540432	DNA topoisomerase III [Vibrio vulnificus].	30.82	662	399	18	2	626	3	642	2e-77	272
rs:WP_017095039	DNA topoisomerase III [Vibrio splendidus].	31.59	592	366	12	2	560	3	588	2e-77	272
rs:WP_045497641	DNA topoisomerase I [Chryseobacterium sp. StRB126].	31.47	699	428	23	1	673	1	674	2e-77	273
rs:WP_019721177	DNA topoisomerase III [Bacillus coagulans].	29.71	727	447	20	3	683	5	713	2e-77	274
rs:WP_044833425	DNA topoisomerase III [Thalassomonas actiniarum].	30.78	640	397	15	1	601	1	633	2e-77	272
rs:WP_037420090	DNA topoisomerase III [Shewanella xiamenensis].	30.90	644	365	15	1	581	1	627	2e-77	273
rs:WP_034525879	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	29.18	699	451	19	1	677	1	677	2e-77	273
rs:WP_021462518	DNA topoisomerase III [Gallibacterium anatis].	29.61	645	402	16	1	614	1	624	2e-77	273
rs:WP_025068869	DNA topoisomerase I [Bacteroides gallinarum].	28.43	707	448	20	1	676	1	680	2e-77	273
rs:WP_021712669	DNA topoisomerase III [Vibrio ezurae].	31.32	613	361	19	2	571	3	598	2e-77	272
rs:WP_005833407	DNA topoisomerase III [Brevibacillus agri].	29.06	733	458	19	1	686	1	718	2e-77	274
rs:WP_045594548	DNA topoisomerase III [Vibrio vulnificus].	30.66	662	400	18	2	626	3	642	2e-77	272
rs:WP_000108741	MULTISPECIES: DNA topoisomerase [Bacilli].	29.78	722	442	18	3	675	4	709	2e-77	273
rs:WP_046557200	DNA topoisomerase III [Arsukibacterium ikkense].	30.60	621	385	14	1	581	1	615	2e-77	273
rs:WP_020331263	DNA topoisomerase III [Vibrio fluvialis].	30.94	627	364	16	2	581	3	607	2e-77	272
rs:WP_017104047	DNA topoisomerase III [Vibrio tasmaniensis].	31.42	592	367	12	2	560	3	588	2e-77	272
rs:WP_039092690	DNA topoisomerase III [Gallibacterium anatis].	30.78	627	373	18	1	581	1	612	2e-77	272
rs:WP_014568628	DNA topoisomerase III [Lactobacillus salivarius].	31.57	662	385	20	2	644	3	615	2e-77	273
rs:WP_039525738	DNA topoisomerase III [Pectobacterium carotovorum].	28.93	643	410	16	1	614	1	625	2e-77	272
rs:WP_042658661	DNA topoisomerase [Aeromonas allosaccharophila].	30.32	620	388	16	1	584	1	612	2e-77	273
rs:WP_015695070	DNA topoisomerase III [Melissococcus plutonius].	30.56	661	393	18	2	644	5	617	2e-77	273
rs:WP_019951680	DNA topoisomerase III [Kushneria aurantia].	28.24	609	394	14	1	584	1	591	2e-77	271
rs:WP_003710611	DNA topoisomerase III [Lactobacillus salivarius].	31.78	664	381	21	2	644	3	615	2e-77	273
rs:WP_044679057	DNA topoisomerase [Streptococcus suis].	33.89	599	353	15	1	587	1	568	2e-77	270
rs:WP_039168663	DNA topoisomerase III [Gallibacterium anatis].	30.14	627	377	16	1	581	1	612	2e-77	272
rs:WP_023045227	DNA topoisomerase III [Photorhabdus temperata].	28.79	639	413	15	1	611	1	625	2e-77	272
rs:WP_034833148	DNA topoisomerase III [Clostridium perfringens].	32.37	658	388	21	2	627	6	638	2e-77	274
rs:WP_038258043	DNA topoisomerase III [Yokenella regensburgei].	31.29	620	369	22	1	581	1	602	2e-77	271
tr:S7WTU8_9BACT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EPR70149.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EPR70149.1};	30.17	633	401	17	70	676	1	618	2e-77	273
rs:WP_028778686	hypothetical protein [Shimazuella kribbensis].	31.37	695	445	17	1	673	1	685	2e-77	273
rs:WP_043715373	hypothetical protein, partial [Symbiobacterium thermophilum].	28.63	723	449	19	3	673	6	713	2e-77	273
rs:WP_019162292	DNA topoisomerase III [Ruminococcus sp. JC304].	31.01	661	399	19	3	627	4	643	2e-77	274
rs:WP_022118737	DNA topoisomerase [Firmicutes bacterium CAG:56].	30.39	668	399	19	3	627	4	648	2e-77	274
rs:WP_006771625	DNA topoisomerase III [[Clostridium] hathewayi].	31.46	658	403	18	3	627	4	646	2e-77	274
rs:WP_039137280	DNA topoisomerase III [Gallibacterium genomosp. 2].	30.46	627	375	16	1	581	1	612	2e-77	271
rs:WP_039847764	DNA topoisomerase III, partial [Haemophilus pittmaniae].	32.10	620	373	20	1	583	1	609	2e-77	271
rs:WP_044748403	DNA topoisomerase III [Bacillus alveayuensis].	31.44	738	421	27	1	681	1	710	2e-77	273
rs:WP_024614465	DNA topoisomerase III [Clostridium sp. Ade.TY].	31.44	652	398	19	3	627	5	634	3e-77	273
rs:WP_008620900	DNA topoisomerase I [Paraprevotella clara].	28.12	697	462	16	1	677	1	678	3e-77	273
rs:WP_005699835	DNA topoisomerase III [Haemophilus parainfluenzae].	32.10	620	373	20	1	583	1	609	3e-77	271
rs:WP_044838231	DNA topoisomerase III [Thalassomonas viridans].	31.00	642	393	17	1	601	1	633	3e-77	272
rs:WP_011847173	DNA topoisomerase III [Shewanella baltica].	30.39	645	384	15	1	591	1	634	3e-77	273
rs:WP_023014977	DNA topoisomerase III [Staphylococcus simulans].	33.07	632	377	20	3	615	4	608	3e-77	273
rs:WP_046019227	DNA topoisomerase III [Marinomonas sp. S3726].	32.01	631	382	17	1	598	1	617	3e-77	271
rs:WP_032594315	DNA topoisomerase I [Bacteroides fragilis].	28.76	699	453	19	1	677	1	676	3e-77	273
rs:WP_031645736	DNA topoisomerase [Listeria monocytogenes].	29.89	726	436	21	3	675	4	709	3e-77	273
rs:WP_023056934	DNA topoisomerase [Prevotella sp. BV3P1].	30.07	715	435	21	1	684	1	681	3e-77	273
rs:WP_008987582	DNA topoisomerase III [Photobacterium leiognathi].	31.24	637	398	18	2	606	3	631	3e-77	272
tr:M5QU49_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.92	665	398	19	3	646	5	622	3e-77	272
rs:WP_005760640	DNA topoisomerase III [Pasteurella bettyae].	32.59	626	355	23	1	581	1	604	3e-77	271
rs:WP_032562869	DNA topoisomerase I [Bacteroides fragilis].	30.42	710	447	21	1	684	1	689	3e-77	273
tr:F9Q6Z6_9PAST	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.10	620	373	20	1	583	1	609	3e-77	271
rs:WP_022030218	DNA topoisomerase [Clostridium hathewayi CAG:224].	31.46	658	403	18	3	627	4	646	3e-77	274
rs:WP_046010027	DNA topoisomerase III [Oleispira antarctica].	31.12	649	387	20	1	594	1	644	3e-77	272
rs:WP_002576229	DNA topoisomerase III [[Clostridium] bolteae].	29.04	699	441	19	2	671	5	677	3e-77	273
rs:WP_010073946	DNA topoisomerase III [Clostridium cellulovorans].	30.64	656	400	19	3	627	5	636	3e-77	273
rs:WP_006714205	DNA topoisomerase III [Vibrio ichthyoenteri].	29.77	702	428	21	1	659	1	680	3e-77	273
rs:WP_034872068	DNA topoisomerase III [Enterococcus faecium].	30.25	628	378	16	2	614	3	585	3e-77	273
rs:WP_038693551	DNA topoisomerase III [Paenibacillus stellifer].	30.05	639	388	16	3	615	4	609	3e-77	273
rs:WP_044337321	DNA topoisomerase III [Bacillus aquimaris].	31.19	654	394	19	3	627	5	631	3e-77	273
rs:WP_024727223	DNA topoisomerase III [Clostridiales bacterium VE202-09].	31.72	662	386	21	2	636	4	626	3e-77	273
rs:WP_045438429	DNA topoisomerase III [bacterium UASB270].	30.18	656	400	20	3	626	4	633	3e-77	272
rs:WP_045048080	DNA topoisomerase III [Rouxiella chamberiensis].	31.12	617	375	18	1	579	1	605	3e-77	271
rs:WP_007985230	DNA topoisomerase III [Glaciecola chathamensis].	30.77	611	386	11	1	581	1	604	3e-77	271
rs:WP_021956947	DNA topoisomerase [Eubacterium sp. CAG:115].	28.71	714	435	17	1	673	1	681	3e-77	272
rs:WP_046339371	DNA topoisomerase III [Pasteurella multocida].	32.07	633	361	20	1	581	1	616	3e-77	271
rs:WP_006819591	DNA topoisomerase III [Yokenella regensburgei].	31.29	620	369	22	1	581	1	602	3e-77	271
rs:WP_044005117	DNA topoisomerase III [Lactobacillus salivarius].	31.42	662	386	20	2	644	3	615	3e-77	272
rs:WP_039419382	DNA topoisomerase I [Porphyromonas gulae].	29.96	701	440	19	1	676	1	675	4e-77	272
rs:WP_038563885	DNA topoisomerase III [Terribacillus aidingensis].	31.38	647	406	16	3	627	5	635	4e-77	273
rs:WP_022512351	DNA topoisomerase [Clostridium clostridioforme CAG:511].	30.86	661	399	19	3	627	4	642	4e-77	273
rs:WP_032812369	DNA topoisomerase I [Bacteroides xylanisolvens].	29.87	703	443	22	1	676	1	680	4e-77	273
rs:WP_007366263	DNA topoisomerase III [Porphyromonas uenonis].	31.00	713	426	23	4	682	7	687	4e-77	272
rs:WP_005696836	DNA topoisomerase III [Haemophilus parainfluenzae].	32.26	620	372	20	1	583	1	609	4e-77	271
rs:WP_017085070	DNA topoisomerase III [Vibrio splendidus].	31.59	592	366	12	2	560	3	588	4e-77	271
rs:WP_037005304	DNA topoisomerase, partial [Pseudomonas stutzeri].	30.76	595	371	10	1	561	1	588	4e-77	270
rs:WP_010676165	DNA topoisomerase [Aeromonas caviae].	30.16	620	389	16	1	584	1	612	4e-77	272
rs:WP_036989946	DNA topoisomerase III [Pseudomonas bauzanensis].	29.03	689	418	19	1	646	1	661	4e-77	271
rs:WP_032542968	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	30.80	711	434	24	1	684	1	680	4e-77	272
rs:WP_021421870	DNA topoisomerase III [Peptoclostridium difficile].	33.06	599	358	15	1	587	1	568	4e-77	269
tr:A0A081C7G9_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.18	656	400	20	3	626	5	634	4e-77	272
rs:WP_002595835	DNA topoisomerase III [[Clostridium] clostridioforme].	28.76	699	443	19	2	671	5	677	4e-77	272
rs:WP_010274993	DNA topoisomerase III [Paenibacillus senegalensis].	30.09	638	384	16	3	614	4	605	4e-77	273
rs:WP_005232250	DNA topoisomerase III [Enterococcus casseliflavus].	30.25	628	378	16	2	614	3	585	4e-77	272
rs:WP_039264698	DNA topoisomerase III [Enterobacter cloacae].	29.26	639	406	14	1	610	1	622	4e-77	271
rs:WP_036880331	DNA topoisomerase I [Prevotella buccalis].	30.80	711	434	24	1	684	1	680	4e-77	272
rs:WP_015535784	DNA topoisomerase III, bacteria and conjugative plasmid [Faecalitalea cylindroides].	28.86	700	443	19	1	671	1	674	4e-77	272
rs:WP_003524410	DNA topoisomerase III [[Clostridium] clostridioforme].	30.86	661	399	19	3	627	4	642	4e-77	273
rs:WP_022339504	DNA topoisomerase III [Bacteroides sp. CAG:714].	30.15	650	398	14	1	608	45	680	4e-77	274
rs:WP_003250827	DNA topoisomerase III [Geobacillus thermoglucosidasius].	30.51	731	439	23	1	682	1	711	4e-77	273
rs:WP_033937544	DNA topoisomerase III [Pseudomonas aeruginosa].	28.89	682	421	18	1	641	1	659	4e-77	271
rs:WP_033025373	DNA topoisomerase III [Geobacillus sp. CAMR5420].	29.55	660	410	18	3	646	4	624	4e-77	272
rs:WP_002593270	DNA topoisomerase III [[Clostridium] clostridioforme].	30.86	661	399	19	3	627	4	642	4e-77	273
rs:WP_008376150	DNA topoisomerase III [Enterococcus sp. C1].	30.52	629	375	16	2	614	3	585	5e-77	272
rs:WP_046740998	DNA topoisomerase III [Lampropedia sp. CT6].	28.68	760	448	23	3	687	5	745	5e-77	277
rs:WP_035889396	DNA topoisomerase III [Kosakonia radicincitans].	28.68	659	425	16	1	629	1	644	5e-77	271
rs:WP_004384681	DNA topoisomerase I [Prevotella veroralis].	30.74	693	431	19	4	673	5	671	5e-77	272
rs:WP_020959943	DNA topoisomerase III [Geobacillus sp. JF8].	28.59	717	469	19	1	681	1	710	5e-77	273
rs:WP_013400955	MULTISPECIES: DNA topoisomerase III [Geobacillus].	30.04	729	443	21	1	681	1	710	5e-77	273
rs:WP_009381486	DNA topoisomerase III [Megasphaera genomosp. type_1].	34.18	594	340	16	3	580	5	563	5e-77	269
rs:WP_003705193	DNA topoisomerase III [Lactobacillus salivarius].	31.42	662	386	20	2	644	3	615	5e-77	272
rs:WP_023351307	DNA topoisomerase 3 [Staphylococcus capitis].	31.39	634	385	15	3	615	4	608	5e-77	272
rs:WP_021825728	DNA topoisomerase III [Prevotella salivae].	31.11	704	414	22	4	673	5	671	5e-77	272
rs:WP_005698708	DNA topoisomerase III [Haemophilus parainfluenzae].	32.10	620	373	20	1	583	1	609	5e-77	271
rs:WP_027709546	DNA topoisomerase III [Zooshikella ganghwensis].	30.58	641	373	17	1	581	1	629	5e-77	271
rs:WP_019226534	hypothetical protein [Dehalobacter sp. E1].	28.03	710	450	17	1	671	1	688	5e-77	272
rs:WP_017056476	DNA topoisomerase III [Vibrio kanaloae].	31.08	592	369	12	2	560	3	588	5e-77	271
tr:H5SNX8_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.58	720	440	22	3	680	12	706	5e-77	275
rs:WP_010846448	DNA topoisomerase [Xenorhabdus nematophila].	29.79	658	419	15	1	629	1	644	5e-77	271
rs:WP_012822377	DNA topoisomerase III [Pectobacterium wasabiae].	28.17	646	425	13	1	620	1	633	5e-77	271
rs:WP_031872959	DNA topoisomerase III, partial [Staphylococcus aureus].	33.06	602	362	16	3	589	4	579	5e-77	270
rs:WP_045754926	DNA topoisomerase I [Sphingobacterium sp. PM2-P1-29].	30.04	709	450	19	1	676	1	696	5e-77	272
tr:D4MPC5_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.01	673	405	18	3	627	4	658	5e-77	273
rs:WP_045467535	DNA topoisomerase III [Burkholderiales bacterium GJ-E10].	28.92	664	427	17	1	640	1	643	5e-77	272
rs:WP_044164756	DNA topoisomerase III [Bacteroides reticulotermitis].	30.63	653	390	15	1	604	1	639	5e-77	273
tr:F3QUZ7_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EGG53247.1};	29.14	700	444	20	4	677	5	678	5e-77	272
tr:E6UKV8_RUMA7	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.75	669	421	17	33	678	20	662	5e-77	271
rs:WP_008408467	DNA topoisomerase III [Bacillus isronensis].	29.10	725	462	18	1	682	1	716	5e-77	273
rs:WP_040266123	DNA topoisomerase III [Serratia symbiotica].	30.34	613	384	17	1	581	1	602	5e-77	271
rs:WP_033732847	DNA topoisomerase III [Pantoea vagans].	30.58	618	376	16	1	581	1	602	5e-77	270
rs:WP_031543238	DNA topoisomerase III, partial [Lachnospiraceae bacterium AC2014].	31.04	625	363	18	1	585	1	597	6e-77	270
rs:WP_033010165	DNA topoisomerase III [Geobacillus stearothermophilus].	30.17	663	402	20	3	646	4	624	6e-77	272
rs:WP_046856132	DNA topoisomerase III [Pseudomonas sp. CCOS191].	29.17	672	427	18	1	641	1	654	6e-77	271
rs:WP_004748460	DNA topoisomerase III [Vibrio tubiashii].	31.70	612	379	14	2	581	3	607	6e-77	271
rs:WP_025809633	DNA topoisomerase III [Bacillus licheniformis].	30.37	708	424	23	3	679	4	673	6e-77	273
rs:WP_046005476	DNA topoisomerase III [Pseudoalteromonas rubra].	31.46	623	381	17	1	590	1	610	6e-77	271
rs:WP_006777725	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	29.42	639	405	15	1	610	1	622	6e-77	271
rs:WP_019807124	DNA topoisomerase III [Osedax symbiont Rs1].	31.99	622	373	17	1	587	1	607	6e-77	271
rs:WP_028593375	DNA topoisomerase III [Paenibacillus assamensis].	29.87	673	400	19	3	647	4	632	6e-77	272
rs:WP_004724160	DNA topoisomerase III [Vibrio furnissii].	30.53	619	377	13	2	581	3	607	6e-77	271
rs:WP_014204652	DNA topoisomerase III [Vibrio furnissii].	30.53	619	377	13	2	581	3	607	6e-77	271
rs:WP_017072510	DNA topoisomerase III [Vibrio splendidus].	31.78	601	353	14	2	560	3	588	6e-77	271
rs:WP_023102544	hypothetical protein [Pseudomonas aeruginosa].	28.74	682	422	18	1	641	1	659	6e-77	271
tr:A6CP00_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.13	652	403	19	4	627	1	634	6e-77	272
rs:WP_046302819	DNA topoisomerase III [Grimontia sp. AD028].	31.19	622	373	17	2	585	3	607	6e-77	271
rs:WP_045608605	DNA topoisomerase III [Vibrio vulnificus].	30.66	662	400	18	2	626	3	642	6e-77	271
rs:WP_042536416	DNA topoisomerase III [Anoxybacillus ayderensis].	29.79	668	395	19	3	646	4	621	6e-77	272
rs:WP_037031292	DNA topoisomerase III [Pseudomonas sp. HPB0071].	28.08	698	435	20	1	645	1	684	6e-77	273
rs:WP_008864255	DNA topoisomerase III [Parasutterella excrementihominis].	29.89	619	382	17	1	579	1	607	6e-77	270
rs:WP_044744310	DNA topoisomerase III [Anoxybacillus sp. ATCC BAA-2555].	29.55	660	410	18	3	646	4	624	6e-77	272
rs:WP_038510307	DNA topoisomerase III [Vibrio coralliilyticus].	31.05	612	383	13	2	581	3	607	6e-77	271
rs:WP_036632665	DNA topoisomerase I [Parabacteroides distasonis].	28.29	700	456	19	1	677	1	677	6e-77	272
rs:WP_046029173	DNA topoisomerase III [Vibrio vulnificus].	30.66	662	400	18	2	626	3	642	6e-77	271
rs:WP_045465464	DNA topoisomerase III [Burkholderiales bacterium GJ-E10].	29.35	627	409	12	1	610	1	610	6e-77	272
rs:WP_046893476	DNA topoisomerase III [Morganella morganii].	31.84	625	359	21	1	581	1	602	7e-77	271
rs:WP_006775893	DNA topoisomerase III [[Clostridium] hathewayi].	29.08	698	442	19	2	671	5	677	7e-77	272
rs:WP_035779841	DNA topoisomerase III [Butyrivibrio sp. MC2013].	31.04	625	363	18	1	585	1	597	7e-77	270
rs:WP_038903512	DNA topoisomerase III [Dickeya zeae].	28.28	647	420	12	1	618	1	632	7e-77	271
rs:WP_017045245	DNA topoisomerase III [Vibrio ordalii].	31.65	613	378	15	2	581	3	607	7e-77	271
rs:WP_045619965	DNA topoisomerase III [Vibrio vulnificus].	30.54	668	405	18	2	632	3	648	7e-77	271
rs:WP_002586183	DNA topoisomerase III [[Clostridium] clostridioforme].	30.86	661	399	19	3	627	4	642	7e-77	273
rs:WP_010094284	DNA topoisomerase III [Ornithinibacillus scapharcae].	30.65	633	401	18	3	615	5	619	7e-77	272
rs:WP_009530028	DNA topoisomerase III [Peptostreptococcaceae bacterium CM5].	34.11	604	351	16	2	595	4	570	7e-77	268
rs:WP_004377587	DNA topoisomerase I [Prevotella oris].	30.48	702	428	22	1	673	2	672	7e-77	271
rs:WP_032608280	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	29.26	639	406	14	1	610	1	622	7e-77	271
rs:WP_040528706	DNA topoisomerase III [Grimontia hollisae].	31.61	620	373	16	2	585	3	607	7e-77	270
rs:WP_037440266	DNA topoisomerase I [Sphingobacterium antarcticum].	30.77	715	429	23	1	682	1	682	7e-77	271
rs:WP_002479576	DNA topoisomerase III [Staphylococcus simulans].	33.07	632	377	20	3	615	4	608	7e-77	272
rs:WP_032108805	DNA topoisomerase III [Haemophilus sp. FF7].	32.15	619	368	19	1	581	1	605	7e-77	270
rs:WP_001177801	DNA topoisomerase III [Escherichia coli].	29.33	641	405	19	1	610	1	624	7e-77	271
rs:WP_037305170	hypothetical protein [Ruminococcus albus].	29.75	669	421	17	33	678	14	656	7e-77	271
rs:WP_039627610	DNA topoisomerase III [Vibrio ichthyoenteri].	31.76	595	359	15	2	560	3	586	7e-77	271
rs:WP_019468637	MULTISPECIES: DNA topoisomerase III [Staphylococcus].	32.00	625	394	15	3	615	4	609	7e-77	272
rs:WP_026003740	DNA topoisomerase III [Pseudomonas luteola].	27.75	699	439	20	1	645	1	687	8e-77	273
rs:WP_033783268	DNA topoisomerase III [Pantoea sp. 9140].	30.58	618	376	16	1	581	1	602	8e-77	270
rs:WP_040552170	DNA topoisomerase III, partial [Rheinheimera nanhaiensis].	28.84	631	393	12	1	581	1	625	8e-77	270
rs:WP_039636260	DNA topoisomerase III [Clostridium argentinense].	31.94	645	403	18	3	626	5	634	8e-77	272
tr:D4V835_BACVU	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFG17986.1};	29.17	696	449	19	4	677	5	678	8e-77	271
rs:WP_002602051	DNA topoisomerase III [[Clostridium] hathewayi].	30.70	658	408	18	3	627	4	646	8e-77	273
rs:WP_005384913	DNA topoisomerase III [Vibrio alginolyticus].	30.11	621	377	14	2	581	3	607	8e-77	270
rs:WP_023983524	hypothetical protein [Prevotella oralis].	30.00	710	436	25	1	677	1	682	8e-77	271
rs:WP_022201063	DNA topoisomerase [Clostridium clostridioforme CAG:132].	30.71	661	400	19	3	627	4	642	8e-77	272
rs:WP_046218684	DNA topoisomerase III [Photobacterium halotolerans].	30.67	613	390	13	2	585	3	609	8e-77	271
rs:WP_001177799	DNA topoisomerase III [Escherichia coli].	29.06	640	408	19	1	610	1	624	8e-77	271
rs:WP_023205275	DNA topoisomerase III [Salmonella enterica].	29.26	639	406	14	1	610	1	622	8e-77	271
rs:WP_014064795	DNA topoisomerase III [Haemophilus parainfluenzae].	31.99	619	375	19	1	583	1	609	8e-77	270
rs:WP_006879407	DNA topoisomerase III [Vibrio brasiliensis].	31.49	616	375	14	2	581	3	607	8e-77	270
rs:WP_004115565	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	29.42	639	405	15	1	610	1	622	8e-77	271
rs:WP_017049114	DNA topoisomerase III [Vibrio ordalii].	31.65	613	378	15	2	581	3	607	8e-77	270
rs:WP_043008804	DNA topoisomerase III [Vibrio coralliilyticus].	31.05	612	383	13	2	581	3	607	8e-77	270
rs:WP_040193168	DNA topoisomerase III [Clostridium sp. CL-6].	31.02	648	409	18	3	627	5	637	8e-77	272
rs:WP_046147969	DNA topoisomerase I [Parabacteroides goldsteinii].	30.14	710	441	23	1	684	1	681	8e-77	271
rs:WP_016268745	DNA topoisomerase III [Bacteroides thetaiotaomicron].	29.22	705	456	18	1	684	1	683	8e-77	271
rs:WP_035331343	DNA topoisomerase III [Bacillus firmus].	29.63	739	436	23	1	682	1	712	8e-77	272
tr:K5Y4M0_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKN08087.1};	29.17	696	449	19	4	677	5	678	8e-77	271
rs:WP_002541082	DNA topoisomerase III [Grimontia indica].	31.35	622	372	16	2	585	3	607	9e-77	270
rs:WP_019561538	DNA topoisomerase III [Caldimonas manganoxidans].	30.69	743	413	30	3	673	5	717	9e-77	275
tr:A0A098ESY6_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.80	724	454	20	1	686	3	717	9e-77	272
rs:WP_036833466	DNA topoisomerase III [Pontibacillus litoralis].	30.52	652	407	20	3	627	5	637	9e-77	272
rs:WP_035604100	DNA topoisomerase III [Hylemonella gracilis].	29.22	746	444	23	3	680	4	733	9e-77	276
tr:D4M0W5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.84	704	446	19	2	676	5	682	9e-77	271
rs:WP_025531347	DNA topoisomerase III [[Clostridium] hathewayi].	30.70	658	408	18	3	627	4	646	9e-77	272
rs:WP_045184773	DNA topoisomerase III [Photobacterium angustum].	31.34	603	377	14	2	574	3	598	9e-77	270
rs:WP_042483778	DNA topoisomerase III [Vibrio diazotrophicus].	30.34	613	386	12	2	581	3	607	9e-77	270
rs:WP_017635824	DNA topoisomerase III [Vibrio sp. 712i1].	30.27	621	376	15	2	581	3	607	9e-77	270
rs:WP_016486405	DNA topoisomerase III [Pseudomonas putida].	28.21	670	434	15	1	640	1	653	9e-77	270
rs:WP_025078801	DNA topoisomerase I [Prevotella fusca].	30.62	699	424	21	4	673	5	671	9e-77	271
rs:WP_039429996	DNA topoisomerase III [Vibrio navarrensis].	30.67	613	384	14	2	581	3	607	9e-77	270
rs:WP_013060258	DNA topoisomerase III [Yersinia pestis].	29.49	607	396	11	1	581	1	601	9e-77	271
rs:WP_004313571	MULTISPECIES: DNA topoisomerase III [Bacteroides].	30.77	624	387	14	1	588	1	615	1e-76	272
rs:WP_036790611	DNA topoisomerase I [Porphyromonas canoris].	30.24	711	414	23	4	673	5	674	1e-76	271
rs:WP_036693314	DNA topoisomerase III [Paenibacillus sp. FSL R7-269].	30.61	637	385	17	3	615	4	607	1e-76	271
tr:A0A015WCI0_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EXZ05162.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EXZ05162.1};	28.74	696	451	19	4	677	5	677	1e-76	271
rs:WP_003145958	DNA topoisomerase III [Gemella haemolysans].	30.54	645	412	15	3	638	4	621	1e-76	271
tr:W7Z0Q0_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.36	652	394	21	2	627	4	634	1e-76	272
rs:WP_010128333	DNA topoisomerase III [Haemophilus sputorum].	31.22	615	377	19	1	581	1	603	1e-76	270
rs:WP_010287696	DNA topoisomerase III [Kurthia massiliensis].	31.10	717	440	23	1	676	1	704	1e-76	271
tr:Q67NT6_SYMTH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.63	723	449	19	3	673	6	713	1e-76	273
rs:WP_004797795	DNA topoisomerase III [[Eubacterium] dolichum].	28.90	699	442	19	2	671	5	677	1e-76	271
rs:WP_031644658	DNA topoisomerase [Listeria monocytogenes].	29.75	726	437	21	3	675	4	709	1e-76	271
rs:WP_016793847	DNA topoisomerase III [Vibrio cyclitrophicus].	31.25	592	368	12	2	560	3	588	1e-76	270
rs:WP_026050788	DNA topoisomerase III [Vibrio vulnificus].	30.97	662	398	19	2	626	3	642	1e-76	270
rs:WP_008024816	MULTISPECIES: DNA topoisomerase III [Bacteroides].	30.77	624	387	14	1	588	1	615	1e-76	272
rs:WP_045974983	DNA topoisomerase III [Vibrio neptunius].	30.72	612	385	13	2	581	3	607	1e-76	270
rs:WP_045588988	DNA topoisomerase III [Vibrio vulnificus].	30.66	662	400	18	2	626	3	642	1e-76	270
rs:WP_021906870	DNA topoisomerase [Eubacterium sp. CAG:146].	31.83	666	376	21	2	627	3	630	1e-76	271
rs:WP_022739163	DNA topoisomerase III [Laceyella sacchari].	29.57	700	463	13	1	676	1	694	1e-76	271
rs:WP_016313465	DNA topoisomerase III [Paenibacillus barengoltzii].	29.43	666	414	18	3	646	4	635	1e-76	271
rs:WP_013692761	DNA topoisomerase III [Pseudomonas brassicacearum].	29.20	661	419	15	1	629	1	644	1e-76	270
rs:WP_008645574	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	30.14	710	441	23	1	684	1	681	1e-76	271
rs:WP_032586616	DNA topoisomerase I [Bacteroides fragilis].	30.20	712	446	21	1	684	1	689	1e-76	271
rs:WP_039467859	DNA topoisomerase III [Vibrio vulnificus].	30.66	662	400	18	2	626	3	642	1e-76	270
rs:WP_007391353	DNA topoisomerase [Megasphaera sp. UPII 199-6].	29.92	665	409	18	1	630	1	643	1e-76	271
rs:WP_024523753	DNA topoisomerase III [Edwardsiella hoshinae].	29.90	612	388	17	1	581	1	602	1e-76	270
rs:WP_034949922	DNA topoisomerase III, partial [Erwinia oleae].	28.39	641	418	12	1	614	1	627	1e-76	270
rs:WP_010437081	DNA topoisomerase III [Vibrio cyclitrophicus].	31.25	592	368	12	2	560	3	588	1e-76	270
rs:WP_005944290	DNA topoisomerase III [Bacteroides massiliensis].	29.72	710	444	21	1	684	1	681	1e-76	271
rs:WP_038539664	DNA topoisomerase III [Bacillus sp. X1(2014)].	30.18	666	399	18	3	646	4	625	1e-76	271
gpu:CP009928_113	DNA topoisomerase I [Chryseobacterium gallinarum]	29.76	709	444	21	1	682	1	682	1e-76	271
rs:WP_019823776	DNA topoisomerase III [Vibrio splendidus].	31.25	592	368	12	2	560	3	588	1e-76	270
rs:WP_033907348	DNA topoisomerase III [Vibrio sp. OY15].	30.11	621	377	14	2	581	3	607	1e-76	270
rs:WP_025333127	DNA topoisomerase III [Paenibacillus sabinae].	29.83	637	390	16	3	615	4	607	1e-76	271
rs:WP_035048305	DNA topoisomerase III [Anoxybacillus sp. KU2-6(11)].	29.77	665	399	19	3	646	4	621	1e-76	271
rs:WP_032088529	DNA topoisomerase III [Bacillus aquimaris].	29.28	724	457	19	1	681	1	712	1e-76	271
rs:WP_040216197	DNA topoisomerase III [Haemophilus parahaemolyticus].	31.96	607	369	16	1	574	1	596	1e-76	270
rs:WP_016792776	DNA topoisomerase III [Vibrio cyclitrophicus].	31.25	592	368	12	2	560	3	588	1e-76	270
rs:WP_042890171	DNA topoisomerase III [Enterococcus faecalis].	30.37	629	376	16	2	614	3	585	1e-76	271
rs:WP_045167922	DNA topoisomerase I [Prevotella intermedia].	31.13	697	420	23	4	673	5	668	1e-76	271
rs:WP_043904536	DNA topoisomerase III [Geobacillus stearothermophilus].	29.85	737	444	23	1	686	1	715	1e-76	271
rs:WP_008728394	DNA topoisomerase III [Erysipelotrichaceae bacterium 2_2_44A].	28.90	699	442	19	2	671	5	677	1e-76	271
tr:D4KA47_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.90	699	442	19	2	671	4	676	1e-76	271
rs:WP_028402778	DNA topoisomerase III [Bacillus panaciterrae].	29.22	705	443	22	1	661	1	693	1e-76	271
tr:D6D8L2_9BACE	SubName: Full=Bacteroides xylanisolvens XB1A draft genome {ECO:0000313|EMBL:CBK66357.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBK66357.1};	30.77	624	387	14	1	588	1	615	1e-76	271
rs:WP_014576643	DNA topoisomerase III [Marinobacter adhaerens].	29.08	643	427	10	1	615	1	642	1e-76	271
rs:WP_009381396	DNA topoisomerase [Megasphaera genomosp. type_1].	29.92	665	409	18	1	630	1	643	1e-76	271
rs:WP_010731205	DNA topoisomerase III [Enterococcus faecium].	29.75	726	437	21	3	675	4	709	1e-76	271
rs:WP_036408089	DNA topoisomerase III [Morganella morganii].	31.78	623	362	21	1	581	1	602	1e-76	270
rs:WP_006318480	DNA topoisomerase III [Anoxybacillus flavithermus].	30.23	665	396	19	3	646	4	621	1e-76	271
rs:WP_042407884	DNA topoisomerase III [Geobacillus caldoxylosilyticus].	29.77	729	445	22	1	681	1	710	1e-76	271
rs:WP_023559145	DNA topoisomerase III [Brevibacillus panacihumi].	31.81	657	395	19	3	627	5	640	1e-76	271
rs:WP_042323003	DNA topoisomerase III [Burkholderia ginsengisoli].	29.09	667	413	19	1	629	1	645	1e-76	270
rs:WP_047104534	DNA topoisomerase III [Vibrio alginolyticus].	30.11	621	377	14	2	581	3	607	1e-76	270
rs:WP_017764797	DNA topoisomerase III [Aeromonas hydrophila].	29.91	652	414	16	1	624	1	637	1e-76	270
rs:WP_016798141	DNA topoisomerase III [Vibrio cyclitrophicus].	31.25	592	368	12	2	560	3	588	1e-76	270
rs:WP_036616528	DNA topoisomerase I [Parabacteroides distasonis].	30.14	710	441	23	1	684	1	681	1e-76	271
rs:WP_016783801	DNA topoisomerase III [Vibrio cyclitrophicus].	31.25	592	368	12	2	560	3	588	1e-76	270
rs:WP_045069951	DNA topoisomerase III [Photobacterium leiognathi].	32.12	604	371	17	2	574	3	598	1e-76	270
rs:WP_005567881	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	31.31	626	370	18	1	581	1	611	1e-76	270
rs:WP_041642718	DNA topoisomerase III, partial [Magnetococcus marinus].	31.86	543	345	12	41	560	3	543	2e-76	269
rs:WP_040118093	DNA topoisomerase III [Enterobacter cloacae].	29.11	639	407	14	1	610	1	622	2e-76	270
tr:B6AP75_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.00	610	394	15	1	584	1	603	2e-76	270
tr:D4JTZ1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.90	699	442	19	2	671	5	677	2e-76	271
rs:WP_033555858	DNA topoisomerase III [Escherichia coli].	29.06	640	408	19	1	610	1	624	2e-76	270
rs:WP_029593103	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	29.11	639	407	14	1	610	1	622	2e-76	270
rs:WP_027321998	DNA topoisomerase III [Bacillus sp. URHB0009].	30.26	737	433	23	1	682	1	711	2e-76	271
rs:WP_034113353	DNA topoisomerase III [Pseudomonas fluorescens].	28.10	669	434	17	1	638	1	653	2e-76	270
rs:WP_024721442	DNA topoisomerase III [Clostridiales bacterium VE202-01].	32.23	633	388	18	3	615	5	616	2e-76	271
rs:WP_038938912	DNA topoisomerase III [Vibrio vulnificus].	30.97	662	398	19	2	626	3	642	2e-76	270
rs:WP_045612368	DNA topoisomerase III [Vibrio vulnificus].	30.97	662	398	19	2	626	3	642	2e-76	270
rs:WP_009089894	DNA topoisomerase III [Pantoea sp. Sc1].	30.48	630	361	21	1	581	1	602	2e-76	269
rs:WP_032636758	DNA topoisomerase III [Enterobacter sp. MGH 15].	29.11	639	407	14	1	610	1	622	2e-76	270
rs:WP_046035426	DNA topoisomerase III [Pseudomonas fluorescens].	27.96	658	429	16	1	629	1	642	2e-76	270
rs:WP_026130810	DNA topoisomerase III [Vibrio vulnificus].	30.82	662	399	18	2	626	3	642	2e-76	270
rs:WP_044192291	DNA topoisomerase I [Parabacteroides gordonii].	29.46	672	435	18	28	677	9	663	2e-76	270
rs:WP_007845581	MULTISPECIES: DNA topoisomerase [Chryseobacterium].	31.63	705	424	21	1	673	1	679	2e-76	271
rs:WP_016426347	DNA topoisomerase III [Staphylococcus sp. HGB0015].	31.95	626	392	16	3	615	4	608	2e-76	271
rs:WP_011145395	DNA topoisomerase III [Photorhabdus luminescens].	28.21	638	418	15	1	611	1	625	2e-76	270
rs:WP_009843452	DNA topoisomerase III [Vibrio sp. AND4].	30.39	612	387	14	2	581	3	607	2e-76	270
rs:WP_008925300	DNA topoisomerase III [Pantoea sp. aB].	30.69	619	374	17	1	581	1	602	2e-76	269
rs:WP_009322007	DNA topoisomerase III [Subdoligranulum sp. 4_3_54A2FAA].	28.76	699	443	19	2	671	5	677	2e-76	271
rs:WP_045148393	DNA topoisomerase III [Photobacterium angustum].	31.34	603	377	14	2	574	3	598	2e-76	270
rs:WP_005380714	DNA topoisomerase III [Vibrio alginolyticus].	30.11	621	377	14	2	581	3	607	2e-76	270
rs:WP_018697076	DNA topoisomerase I [Alistipes onderdonkii].	28.39	708	460	20	1	685	1	684	2e-76	271
rs:WP_008956693	DNA topoisomerase III [Halomonas sp. HAL1].	29.56	636	408	13	1	612	1	620	2e-76	269
rs:WP_011262202	DNA topoisomerase III [Aliivibrio fischeri].	30.76	621	366	16	2	574	12	616	2e-76	270
rs:WP_038968960	DNA topoisomerase III [Vibrio vulnificus].	30.66	662	400	18	2	626	3	642	2e-76	270
rs:WP_037404599	DNA topoisomerase III [Serratia sp. Ag2].	28.44	640	413	14	1	614	1	621	2e-76	270
rs:WP_010860920	DNA topoisomerase III [Lysinibacillus sphaericus].	28.73	724	466	17	1	681	1	717	2e-76	271
rs:WP_042342345	DNA topoisomerase III [Escherichia coli].	29.06	640	408	19	1	610	1	624	2e-76	270
rs:WP_045850186	hypothetical protein [Domibacillus enclensis].	29.00	700	449	16	1	664	1	688	2e-76	271
rs:WP_042522502	DNA topoisomerase III [Vibrio alginolyticus].	30.11	621	377	14	2	581	3	607	2e-76	270
rs:WP_036414934	DNA topoisomerase III [Morganella morganii].	31.94	623	361	23	1	581	1	602	2e-76	270
rs:WP_017821143	DNA topoisomerase III [Vibrio alginolyticus].	30.11	621	377	14	2	581	3	607	2e-76	270
rs:WP_003036629	DNA topoisomerase III [Citrobacter freundii].	29.08	643	410	14	1	614	1	626	2e-76	270
rs:WP_022622166	DNA topoisomerase III [Pantoea ananatis].	29.58	612	390	12	1	581	1	602	2e-76	270
rs:WP_047109038	DNA topoisomerase III [Vibrio vulnificus].	31.11	614	380	15	2	581	3	607	2e-76	270
rs:WP_028768377	DNA topoisomerase III [Shewanella fidelis].	29.15	638	410	13	1	601	1	633	2e-76	270
rs:WP_025067905	DNA topoisomerase I [Prevotella denticola].	31.50	711	405	22	3	673	4	672	2e-76	270
rs:WP_017079516	DNA topoisomerase III [Vibrio splendidus].	31.59	592	366	13	2	560	3	588	2e-76	270
rs:WP_004364188	MULTISPECIES: DNA topoisomerase I [Prevotella].	30.29	700	427	19	3	673	4	671	2e-76	270
rs:WP_017048533	DNA topoisomerase III [Vibrio ordalii].	31.65	613	378	15	2	581	3	607	2e-76	269
rs:WP_017346306	DNA topoisomerase III [Pantoea sp. A4].	30.61	624	368	21	1	581	1	602	2e-76	269
tr:F9ZPH5_ACICS	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.56	663	422	15	3	640	1	643	2e-76	270
rs:WP_022041252	DNA topoisomerase III [Bacteroides sp. CAG:702].	30.45	716	398	19	1	630	1	702	2e-76	271
rs:WP_039443542	DNA topoisomerase III [Vibrio navarrensis].	30.05	619	380	12	2	581	3	607	2e-76	270
rs:WP_028685751	DNA topoisomerase III [Phaseolibacter flectens].	30.53	619	374	18	1	578	1	604	2e-76	269
rs:WP_032558157	MULTISPECIES: DNA topoisomerase I [Bacteroides].	28.43	707	459	20	1	684	1	683	2e-76	270
rs:WP_038206707	DNA topoisomerase III [Vibrio tubiashii].	31.37	612	381	13	2	581	3	607	2e-76	269
rs:WP_044129469	DNA topoisomerase III [Vibrio parahaemolyticus].	30.11	621	377	14	2	581	3	607	2e-76	269
rs:WP_027895674	DNA topoisomerase [Megasphaera elsdenii].	30.30	670	411	19	1	636	1	648	2e-76	271
rs:WP_004235547	DNA topoisomerase III [Morganella morganii].	31.94	623	361	23	1	581	1	602	2e-76	269
rs:WP_005681364	MULTISPECIES: DNA topoisomerase I [Bacteroides].	28.43	707	459	20	1	684	1	683	2e-76	270
rs:WP_014016907	DNA topoisomerase [Megasphaera elsdenii].	30.30	670	411	19	1	636	1	648	2e-76	271
rs:WP_040089341	DNA topoisomerase III [Escherichia coli].	29.22	640	407	19	1	610	1	624	2e-76	270
rs:WP_005557593	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	31.79	626	367	19	1	581	1	611	2e-76	269
tr:D0I730_GRIHO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.61	620	373	16	2	585	24	628	2e-76	270
rs:WP_029427001	DNA topoisomerase I [Bacteroides cellulosilyticus].	29.63	702	446	20	1	676	1	680	2e-76	270
rs:WP_019977041	DNA topoisomerase [Empedobacter brevis].	31.14	700	429	22	1	673	1	674	2e-76	270
rs:WP_036887964	DNA topoisomerase I [Prevotella bivia].	30.04	709	416	20	4	673	5	672	2e-76	270
rs:WP_045623503	DNA topoisomerase III [Vibrio vulnificus].	30.58	667	404	18	2	631	3	647	2e-76	269
tr:S7UCG1_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.55	660	410	18	3	646	13	633	2e-76	270
rs:WP_019002781	hypothetical protein [Succinimonas amylolytica].	29.73	730	442	20	1	687	1	702	2e-76	271
rs:WP_044684362	DNA topoisomerase [Streptococcus suis].	33.22	599	357	14	1	587	1	568	2e-76	267
rs:WP_021707943	DNA topoisomerase III [Vibrio azureus].	30.02	613	388	13	2	581	3	607	2e-76	269
rs:WP_004318971	MULTISPECIES: DNA topoisomerase I [Bacteroides].	28.86	700	454	16	1	676	1	680	2e-76	270
rs:WP_008223266	DNA topoisomerase III [Vibrionales bacterium SWAT-3].	30.74	592	371	11	2	560	3	588	2e-76	270
rs:WP_045595832	DNA topoisomerase III [Vibrio vulnificus].	30.58	667	404	18	2	631	3	647	2e-76	269
rs:WP_005800863	DNA topoisomerase I [Bacteroides fragilis].	29.46	706	453	21	1	684	1	683	2e-76	270
rs:WP_003852758	DNA topoisomerase III [Pantoea agglomerans].	30.69	619	374	17	1	581	1	602	2e-76	269
rs:WP_004632114	DNA topoisomerase III [Gemella morbillorum].	30.36	662	391	18	3	638	4	621	2e-76	270
rs:WP_007216070	DNA topoisomerase I [Bacteroides cellulosilyticus].	29.10	708	459	18	1	687	1	686	2e-76	270
rs:WP_033092471	DNA topoisomerase III [Colwellia psychrerythraea].	31.53	628	369	18	1	579	1	616	2e-76	269
rs:WP_015547215	DNA topoisomerase III, bacteria and conjugative plasmid [Alistipes shahii].	28.43	707	459	20	1	684	1	683	2e-76	270
rs:WP_000108743	MULTISPECIES: DNA topoisomerase [Bacilli].	29.75	726	437	21	3	675	4	709	2e-76	271
rs:WP_007151773	DNA topoisomerase III [Marinobacter algicola].	29.98	647	408	15	1	614	1	635	2e-76	271
tr:A0A034TL34_9VIBR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.97	624	376	15	2	581	3	609	2e-76	269
rs:WP_015713669	DNA topoisomerase III [Bifidobacterium longum].	28.50	751	439	26	1	679	1	725	2e-76	271
rs:WP_028905786	DNA topoisomerase I [Prevotella intermedia].	30.13	697	447	18	4	684	5	677	2e-76	270
tr:N2ILA1_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.94	698	436	20	1	645	3	686	2e-76	271
rs:WP_028447326	DNA topoisomerase III [Chitinimonas koreensis].	28.72	672	411	17	1	630	1	646	2e-76	270
rs:WP_039948979	DNA topoisomerase III [Vibrio ichthyoenteri].	31.54	596	359	16	2	560	3	586	2e-76	269
tr:A0A0B5GGH3_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.50	722	444	18	3	675	4	709	2e-76	270
rs:WP_013606785	DNA topoisomerase III [Sphaerochaeta globosa].	29.98	637	405	15	2	615	3	621	3e-76	272
rs:WP_013671966	DNA topoisomerase I [Prevotella denticola].	31.03	696	432	20	3	675	4	674	3e-76	270
rs:WP_033791181	DNA topoisomerase III [Pantoea sp. FF5].	30.08	625	370	17	1	581	1	602	3e-76	269
rs:WP_024617231	DNA topoisomerase III [Pseudomonas fluorescens].	29.35	661	418	15	1	629	1	644	3e-76	270
rs:WP_042558370	DNA topoisomerase III [Pseudomonas fluorescens].	28.48	660	423	13	1	629	1	642	3e-76	269
rs:WP_009038766	DNA topoisomerase III [Bacteroides sp. D22].	30.61	624	388	13	1	588	1	615	3e-76	271
rs:WP_025067452	DNA topoisomerase I [Prevotella denticola].	29.93	715	430	26	1	677	1	682	3e-76	270
rs:WP_039081471	DNA topoisomerase III [Gallibacterium anatis].	30.30	627	376	16	1	581	1	612	3e-76	269
rs:WP_003831767	DNA topoisomerase III [Bifidobacterium breve].	28.50	751	439	26	1	679	1	725	3e-76	271
rs:WP_003235825	DNA topoisomerase III [Pseudomonas fluorescens].	28.57	665	433	15	1	637	1	651	3e-76	269
tr:A0A078SW41_9PORP	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:KDS64711.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KDS64711.1};	28.26	697	454	19	4	677	5	678	3e-76	270
rs:WP_011476268	DNA topoisomerase III [Lactobacillus salivarius].	31.37	663	385	19	2	644	3	615	3e-76	270
rs:WP_039450498	DNA topoisomerase III [Vibrio vulnificus].	30.66	662	400	18	2	626	3	642	3e-76	269
rs:WP_040404641	DNA topoisomerase III, partial [Amphritea japonica].	31.31	610	380	15	1	581	1	600	3e-76	268
rs:WP_040603635	DNA topoisomerase [Parasutterella excrementihominis].	30.06	632	379	17	1	588	1	613	3e-76	268
rs:WP_012154870	DNA topoisomerase III [Shewanella pealeana].	29.94	638	405	14	1	601	1	633	3e-76	270
rs:WP_022497972	DNA topoisomerase [Megasphaera elsdenii CAG:570].	30.30	670	411	19	1	636	1	648	3e-76	270
rs:WP_036768648	DNA topoisomerase III [Photorhabdus asymbiotica].	28.33	639	416	16	1	611	1	625	3e-76	270
rs:WP_011149881	DNA topoisomerase III [Vibrio vulnificus].	31.02	619	384	15	2	586	3	612	3e-76	269
rs:WP_046180764	hypothetical protein [Domibacillus sp. PAMC 80007].	28.51	712	452	18	1	673	1	694	3e-76	270
rs:WP_047035846	DNA topoisomerase III [Lactobacillus salivarius].	31.37	663	385	19	2	644	3	615	3e-76	270
rs:WP_007653480	DNA topoisomerase I [Parabacteroides goldsteinii].	28.94	705	458	18	1	684	1	683	3e-76	270
rs:WP_009092112	DNA topoisomerase [Elizabethkingia anophelis].	30.50	695	433	20	1	673	1	667	3e-76	270
rs:WP_008897065	DNA topoisomerase III [Rheinheimera sp. A13L].	30.20	596	369	14	1	560	1	585	3e-76	269
rs:WP_033524055	DNA topoisomerase III [Bifidobacterium pseudocatenulatum].	27.88	746	450	22	1	679	1	725	3e-76	271
rs:WP_026773238	DNA topoisomerase I [Sediminibacterium sp. OR43].	31.19	699	429	23	1	673	1	673	3e-76	270
tr:F9S2S7_9VIBR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.54	596	359	16	2	560	14	597	3e-76	269
rs:WP_039465481	DNA topoisomerase III [Vibrio navarrensis].	30.21	619	379	13	2	581	3	607	3e-76	269
rs:WP_005467933	DNA topoisomerase [Porphyromonas catoniae].	30.43	700	424	22	4	673	5	671	3e-76	270
rs:WP_041114323	DNA topoisomerase III [Bacillus badius].	29.56	697	463	15	3	676	4	695	3e-76	270
rs:WP_042868977	DNA topoisomerase III [Dickeya sp. NCPPB 569].	28.59	647	418	14	1	618	1	632	3e-76	269
rs:WP_010565137	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	28.19	667	436	14	1	638	1	653	3e-76	269
rs:WP_009228524	DNA topoisomerase I [Prevotella sp. oral taxon 299].	30.14	700	426	21	4	673	5	671	3e-76	270
rs:WP_028862617	DNA topoisomerase III [Psychromonas aquimarina].	31.18	635	377	16	1	596	1	614	3e-76	268
rs:WP_020505068	hypothetical protein [Lamprocystis purpurea].	27.06	739	465	19	3	680	4	729	3e-76	273
rs:WP_033004773	DNA topoisomerase III [Geobacillus sp. WSUCF1].	29.55	660	410	18	3	646	4	624	3e-76	270
rs:WP_022474363	DNA topoisomerase III [Ruminococcus sp. CAG:353].	29.64	685	443	17	2	669	5	667	3e-76	271
rs:WP_043081838	DNA topoisomerase III [Pluralibacter gergoviae].	28.74	682	422	18	1	641	1	659	3e-76	269
rs:WP_040735488	DNA topoisomerase III [Paenibacillus alvei].	30.33	643	385	17	3	615	4	613	3e-76	270
rs:WP_038156149	DNA topoisomerase III [Vibrio sp. B183].	30.88	612	384	13	2	581	3	607	3e-76	269
tr:K4ZT14_PAEAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.33	643	385	17	3	615	11	620	3e-76	270
tr:S4DYY5_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.32	597	358	13	28	611	6	563	3e-76	269
rs:WP_034982849	DNA topoisomerase III [Lactobacillus salivarius].	31.01	661	390	18	2	644	3	615	4e-76	270
rs:WP_004564283	DNA topoisomerase III [Lactobacillus salivarius].	31.37	663	385	19	2	644	3	615	4e-76	270
rs:WP_013123595	DNA topoisomerase III [Thiomonas intermedia].	29.27	632	411	14	1	611	1	617	4e-76	270
rs:WP_004035914	DNA topoisomerase III [Clostridium sp. ASF356].	30.33	643	411	18	3	627	5	628	4e-76	270
rs:WP_013438841	topoisomerase [Enterococcus faecalis].	29.75	726	437	21	3	675	4	709	4e-76	270
rs:WP_016151302	hypothetical protein [Citrobacter sp. KTE151].	28.53	638	412	13	1	610	1	622	4e-76	269
rs:WP_044470732	DNA topoisomerase III [Mannheimia sp. MG13].	32.02	634	348	23	1	581	1	604	4e-76	268
rs:WP_036206169	DNA topoisomerase III [Marinobacter sp. MCTG268].	29.68	657	397	17	1	614	1	635	4e-76	270
rs:WP_008075309	DNA topoisomerase III [Pseudomonas sp. GM79].	27.43	678	427	16	1	638	1	653	4e-76	269
rs:WP_042998113	DNA topoisomerase III [Citrobacter sp. MGH 55].	28.95	639	408	14	1	610	1	622	4e-76	269
rs:WP_013358056	DNA topoisomerase III [Pantoea vagans].	30.42	618	377	16	1	581	1	602	4e-76	268
rs:WP_040659182	DNA topoisomerase III, partial [Neisseria bacilliformis].	32.11	545	330	13	68	577	19	558	4e-76	266
rs:WP_037353282	DNA topoisomerase [Selenomonas sp. FC4001].	29.72	673	413	17	1	629	1	657	4e-76	272
rs:WP_018662174	DNA topoisomerase III [Bacillus acidiproducens].	29.79	725	454	23	3	682	5	719	4e-76	270
rs:WP_005817765	DNA topoisomerase III [Actinobacillus minor].	31.45	620	375	19	1	584	1	606	4e-76	268
rs:WP_045062705	DNA topoisomerase III [Photobacterium leiognathi].	32.24	608	365	18	2	574	3	598	4e-76	269
rs:WP_007173335	DNA topoisomerase I [Prevotella bergensis].	29.86	700	434	20	1	673	2	671	4e-76	270
rs:WP_018692714	hypothetical protein [Algicola sagamiensis].	30.23	622	376	14	1	581	1	605	4e-76	268
rs:WP_034867809	DNA topoisomerase I [Elizabethkingia miricola].	30.64	705	440	21	1	680	1	681	4e-76	270
rs:WP_002343776	MULTISPECIES: DNA topoisomerase III [Lactobacillales].	29.75	726	437	21	3	675	4	709	4e-76	270
rs:WP_020311399	MULTISPECIES: DNA topoisomerase [Megasphaera].	29.45	669	418	18	1	636	1	648	4e-76	270
rs:WP_041335167	DNA topoisomerase III [Marinobacter salarius].	29.68	647	410	14	1	614	1	635	4e-76	270
rs:WP_042094135	DNA topoisomerase III [Escherichia coli].	29.06	640	408	19	1	610	1	624	4e-76	269
rs:WP_002387619	DNA topoisomerase [Enterococcus faecalis].	29.61	726	438	21	3	675	4	709	4e-76	270
rs:WP_046999514	hypothetical protein [Bifidobacterium adolescentis].	27.57	740	451	21	1	677	1	718	5e-76	270
rs:WP_005762746	DNA topoisomerase III [Pasteurella dagmatis].	31.46	658	378	22	1	605	1	638	5e-76	268
rs:WP_006287544	topoisomerase IA [Paenibacillus popilliae].	30.55	671	402	21	3	646	4	637	5e-76	270
rs:WP_028540227	DNA topoisomerase III [Paenibacillus sp. J14].	29.43	666	414	18	3	646	4	635	5e-76	270
rs:WP_006045120	DNA topoisomerase I [Prevotella pallens].	30.29	700	431	19	1	673	2	671	5e-76	269
rs:WP_045480696	DNA topoisomerase III [Vibrio owensii].	30.72	612	385	14	2	581	3	607	5e-76	268
rs:WP_032489173	type I topoisomerase [Enterococcus faecalis].	29.64	722	443	20	3	675	4	709	5e-76	270
rs:WP_008675430	DNA topoisomerase I [Bacteroides sp. 9_1_42FAA].	28.88	696	451	19	4	677	5	678	5e-76	270
rs:WP_008792719	DNA topoisomerase III [Coprobacillus sp. 8_2_54BFAA].	32.45	638	378	20	3	615	5	614	5e-76	270
rs:WP_016488058	DNA topoisomerase III [Pseudomonas putida].	28.83	673	428	17	1	641	1	654	5e-76	268
rs:WP_022354483	DNA topoisomerase III [Bacteroides sp. CAG:875].	31.10	643	394	12	1	603	1	634	5e-76	270
rs:WP_045629174	DNA topoisomerase III [Vibrio vulnificus].	30.66	662	400	18	2	626	3	642	5e-76	268
rs:WP_025988385	DNA topoisomerase III [Burkholderia pseudomallei].	28.94	615	402	13	1	587	1	608	5e-76	269
tr:A0A022NBM7_ENTMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.29	659	404	17	2	644	3	615	5e-76	269
rs:WP_038871241	DNA topoisomerase III [Vibrio jasicida].	30.56	612	386	14	2	581	3	607	5e-76	268
rs:WP_007662652	DNA topoisomerase I [Bacteroides intestinalis].	28.43	707	459	20	1	684	1	683	5e-76	269
rs:WP_006248941	DNA topoisomerase III [Mannheimia haemolytica].	30.10	628	389	17	1	592	1	614	5e-76	268
rs:WP_034882663	DNA topoisomerase III, partial [Gilliamella apicola].	31.12	617	381	18	2	581	8	617	5e-76	268
rs:WP_038179981	DNA topoisomerase III [Vibrio rhizosphaerae].	30.73	628	365	17	2	581	3	608	5e-76	268
rs:WP_035415424	DNA topoisomerase III [Chromohalobacter israelensis].	28.09	648	414	16	2	614	3	633	5e-76	269
rs:WP_036417289	DNA topoisomerase III [Morganella sp. EGD-HP17].	31.78	623	362	23	1	581	1	602	5e-76	268
rs:WP_002352589	MULTISPECIES: DNA topoisomerase [Enterococcus].	29.64	722	443	20	3	675	4	709	5e-76	270
rs:WP_039459217	DNA topoisomerase III [Photobacterium gaetbulicola].	29.97	614	386	14	2	581	3	606	5e-76	268
rs:WP_041057988	DNA topoisomerase III [Vibrio owensii].	30.72	612	385	14	2	581	3	607	5e-76	268
rs:WP_012536731	DNA topoisomerase III [Acidithiobacillus ferrooxidans].	30.48	607	385	17	1	581	1	596	5e-76	269
rs:WP_042906600	DNA topoisomerase III, partial [Haemophilus parasuis].	30.03	646	401	17	1	614	1	627	5e-76	268
rs:WP_044337013	DNA topoisomerase III [Bacillus aquimaris].	29.17	720	463	19	1	681	1	712	6e-76	270
rs:WP_039092466	DNA topoisomerase III [Gallibacterium anatis].	29.46	645	403	16	1	614	1	624	6e-76	269
rs:WP_021900326	DNA topoisomerase [Eggerthella sp. CAG:1427].	30.63	702	432	23	1	676	1	673	6e-76	269
rs:WP_039085585	DNA topoisomerase III [Gallibacterium anatis].	29.46	645	403	16	1	614	1	624	6e-76	269
rs:WP_046101928	DNA topoisomerase III [Pantoea anthophila].	29.94	658	381	23	1	609	1	627	6e-76	268
rs:WP_044023984	DNA topoisomerase III [Vibrio vulnificus].	31.27	614	379	15	2	581	3	607	6e-76	268
rs:WP_009707306	DNA topoisomerase III [Vibrio sp. HENC-03].	30.72	612	385	14	2	581	3	607	6e-76	268
rs:WP_018705508	hypothetical protein [Bacillus fordii].	30.66	662	401	21	3	646	4	625	6e-76	269
rs:WP_017189344	DNA topoisomerase III [Vibrio harveyi].	30.56	612	386	14	2	581	3	607	6e-76	268
rs:WP_042355746	DNA topoisomerase III [Bacillus sp. MT2].	29.53	718	453	19	1	676	1	707	6e-76	270
rs:WP_023414868	hypothetical protein [uncultured Thiohalocapsa sp. PB-PSB1].	29.05	654	413	14	3	618	4	644	6e-76	273
tr:A0A061PRR0_9VIBR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.63	621	380	13	2	581	3	607	6e-76	268
rs:WP_006990687	DNA topoisomerase III [Glaciecola mesophila].	30.23	612	388	12	1	581	1	604	6e-76	268
rs:WP_006256385	DNA topoisomerase I [Alloprevotella tannerae].	29.80	708	430	22	4	673	5	683	6e-76	269
rs:WP_017434187	DNA topoisomerase III [Geobacillus caldoxylosilyticus].	29.77	729	445	22	1	681	1	710	7e-76	270
rs:WP_038896082	DNA topoisomerase III [Vibrio owensii].	30.72	612	385	14	2	581	3	607	7e-76	268
rs:WP_034007122	DNA topoisomerase III [Pseudomonas aeruginosa].	28.59	682	423	18	1	641	1	659	7e-76	268
rs:WP_034857843	DNA topoisomerase III [Enterococcus casseliflavus].	30.21	629	377	16	2	614	3	585	7e-76	269
rs:WP_047340352	DNA topoisomerase [Xanthomonas oryzae].	30.28	677	412	19	1	630	1	664	7e-76	269
rs:WP_020195690	DNA topoisomerase III [Vibrio owensii].	30.72	612	385	14	2	581	3	607	7e-76	268
rs:WP_044362581	DNA topoisomerase III [Vibrio fluvialis].	30.21	619	379	13	2	581	3	607	7e-76	268
rs:WP_025153076	DNA topoisomerase III [Morganella morganii].	31.46	623	364	20	1	581	1	602	7e-76	268
rs:WP_027320953	DNA topoisomerase III [Bacillus sp. URHB0009].	29.86	663	405	18	3	646	4	625	7e-76	269
rs:WP_027409388	DNA topoisomerase III [Anoxybacillus tepidamans].	30.60	621	385	15	3	611	4	590	7e-76	269
rs:WP_013773769	DNA topoisomerase III [Melissococcus plutonius].	30.41	661	394	18	2	644	5	617	7e-76	269
rs:WP_039842429	DNA topoisomerase III [Vibrio owensii].	30.72	612	385	14	2	581	3	607	7e-76	268
rs:WP_027831559	DNA topoisomerase III [Marinobacter sp. HL-58].	28.99	645	417	13	1	614	1	635	7e-76	270
rs:WP_026313232	DNA topoisomerase III [Actinobacillus capsulatus].	31.54	615	381	17	1	584	1	606	7e-76	268
rs:WP_027089380	DNA topoisomerase III [[Clostridium] saccharogumia].	32.34	637	382	20	3	615	5	616	7e-76	270
tr:A0A080KI01_9GAMM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.12	617	381	18	2	581	8	617	7e-76	267
rs:WP_014167642	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	31.15	626	371	18	1	581	1	611	7e-76	268
rs:WP_005751158	DNA topoisomerase III [Pasteurella multocida].	31.80	632	368	20	1	583	1	618	7e-76	268
rs:WP_032101858	DNA topoisomerase III, partial [Anoxybacillus flavithermus].	29.64	668	396	19	3	646	4	621	7e-76	269
rs:WP_009961403	DNA topoisomerase III [Verrucomicrobium spinosum].	27.72	736	464	19	3	684	5	726	7e-76	272
rs:WP_005756024	DNA topoisomerase III [Pasteurella multocida].	30.70	632	375	17	1	583	1	618	7e-76	268
gp:CP002469_2073	DNA topoisomerase III [Vibrio vulnificus MO6-24/O]	31.27	614	379	15	2	581	12	616	8e-76	268
rs:WP_005444645	DNA topoisomerase III [Vibrio harveyi].	30.56	612	386	14	2	581	3	607	8e-76	268
rs:WP_040103605	DNA topoisomerase III [Paenibacillus polymyxa].	29.31	696	454	15	1	661	1	693	8e-76	269
rs:WP_034881273	DNA topoisomerase III [Bifidobacterium pseudocatenulatum].	27.75	746	451	22	1	679	1	725	8e-76	270
rs:WP_005439724	DNA topoisomerase III [Vibrio harveyi].	30.11	621	377	14	2	581	3	607	8e-76	268
rs:WP_039986868	DNA topoisomerase III [Vibrio owensii].	30.56	612	386	14	2	581	3	607	8e-76	268
rs:WP_041848210	DNA topoisomerase III [Bacillus thermoamylovorans].	28.73	717	467	18	1	681	1	709	8e-76	269
rs:WP_010494059	DNA topoisomerase III [Paenibacillus elgii].	29.13	714	414	22	3	667	4	674	8e-76	269
rs:WP_006252007	DNA topoisomerase III [Mannheimia haemolytica].	30.05	629	388	18	1	592	1	614	8e-76	267
rs:WP_011080930	DNA topoisomerase III [Vibrio vulnificus].	31.11	614	380	15	2	581	3	607	8e-76	268
rs:WP_021112534	DNA topoisomerase III family protein [Haemophilus parasuis].	30.03	646	401	17	1	614	1	627	8e-76	268
rs:WP_034736742	DNA topoisomerase I [Chryseobacterium indologenes].	30.80	698	434	21	1	673	1	674	8e-76	269
rs:WP_006708809	DNA topoisomerase III [Serratia symbiotica].	30.18	613	385	17	1	581	1	602	8e-76	267
rs:WP_046553465	DNA topoisomerase III [Arsukibacterium sp. MJ3].	30.58	618	387	13	1	581	1	613	8e-76	268
rs:WP_014195788	DNA topoisomerase III [Geobacillus thermoleovorans].	29.24	660	412	18	3	646	4	624	8e-76	269
rs:WP_040988788	DNA topoisomerase III [Vibrio sp. DCR 1-4-2].	30.94	598	360	15	2	560	3	586	8e-76	268
rs:WP_010370844	DNA topoisomerase III [Pseudoalteromonas piscicida].	31.32	613	371	17	1	578	1	598	8e-76	267
rs:WP_008016669	DNA topoisomerase, partial [Bacteroides xylanisolvens].	29.67	664	431	18	35	677	2	650	9e-76	268
rs:WP_003308699	DNA topoisomerase III [Bacillus thuringiensis].	30.27	697	445	18	2	676	4	681	9e-76	268
rs:WP_014391307	DNA topoisomerase III [Pasteurella multocida].	31.28	633	370	19	1	583	1	618	9e-76	268
rs:WP_023634313	DNA topoisomerase III [Geobacillus sp. MAS1].	29.24	660	412	18	3	646	4	624	9e-76	268
rs:WP_003289344	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	28.61	685	426	22	1	646	1	661	9e-76	268
rs:WP_009766667	DNA topoisomerase III [Sporosarcina newyorkensis].	31.68	606	381	12	1	581	1	598	9e-76	269
rs:WP_028622299	DNA topoisomerase III [Pseudomonas sp. Ant30-3].	28.34	681	427	19	1	641	1	660	9e-76	268
rs:WP_019533711	DNA topoisomerase III [Paenibacillus ginsengihumi].	29.67	664	394	16	3	627	4	633	9e-76	269
rs:WP_042803655	DNA topoisomerase III [Mannheimia haemolytica].	31.05	628	383	17	1	592	1	614	9e-76	267
rs:WP_006717380	DNA topoisomerase III [Aggregatibacter segnis].	31.15	626	371	17	1	581	1	611	9e-76	267
rs:WP_022953535	DNA topoisomerase III [Leucothrix mucor].	29.28	642	387	15	1	581	1	636	9e-76	268
rs:WP_023047535	DNA topoisomerase III [Pseudomonas putida].	28.87	672	429	18	1	641	1	654	9e-76	268
rs:WP_021908894	DNA topoisomerase III bacteria and conjugative plasmid [Prevotella sp. CAG:755].	28.84	697	450	18	1	676	1	672	9e-76	268
rs:WP_035063636	DNA topoisomerase III [Anoxybacillus sp. SK3-4].	29.92	665	398	18	3	646	4	621	9e-76	268
rs:WP_007495750	DNA topoisomerase III [Flavonifractor plautii].	29.43	649	418	15	3	627	5	637	1e-75	269
rs:WP_044202797	DNA topoisomerase III [Pectobacterium carotovorum].	29.06	640	413	15	1	614	1	625	1e-75	268
rs:WP_005546712	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	31.15	626	371	18	1	581	1	611	1e-75	267
rs:WP_045060819	DNA topoisomerase III [Pseudomonas sp. ES3-33].	28.42	658	426	16	1	629	1	642	1e-75	268
rs:WP_044622876	DNA topoisomerase III [Photobacterium gaetbulicola].	29.94	618	389	14	2	585	3	610	1e-75	268
rs:WP_003128167	DNA topoisomerase III [Enterococcus gallinarum].	29.39	626	385	14	2	614	3	584	1e-75	268
rs:WP_025279158	DNA topoisomerase I [Barnesiella viscericola].	28.07	709	462	18	1	683	1	687	1e-75	268
rs:WP_022277691	DNA topoisomerase III [Bacteroides coprophilus CAG:333].	29.64	722	399	21	1	630	1	705	1e-75	269
rs:WP_012824474	DNA topoisomerase III [Halothiobacillus neapolitanus].	28.57	637	411	12	1	610	1	620	1e-75	268
rs:WP_026766366	DNA topoisomerase [Selenomonas ruminantium].	29.53	674	413	17	1	629	1	657	1e-75	271
rs:WP_019098998	DNA topoisomerase III [Pseudomonas putida].	28.15	675	428	16	1	640	1	653	1e-75	268
rs:WP_008620097	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	28.43	707	459	20	1	684	1	683	1e-75	268
rs:WP_005470120	MULTISPECIES: DNA topoisomerase III [Enterococcus].	29.39	626	385	14	2	614	3	584	1e-75	268
rs:WP_021002848	DNA topoisomerase [Streptococcus intermedius].	33.97	577	336	16	1	564	1	545	1e-75	265
rs:WP_044942795	DNA topoisomerase III [Flavonifractor plautii].	29.12	649	420	14	3	627	5	637	1e-75	269
rs:WP_005542694	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	31.37	628	367	19	1	581	1	611	1e-75	267
rs:WP_033626047	DNA topoisomerase [Enterococcus faecalis].	30.21	725	435	20	3	675	4	709	1e-75	269
rs:WP_042385891	DNA topoisomerase III [Geobacillus thermoglucosidasius].	30.45	706	458	18	1	679	1	700	1e-75	268
rs:WP_017817824	DNA topoisomerase III [Vibrio harveyi].	30.56	612	386	14	2	581	3	607	1e-75	267
rs:WP_033470610	DNA topoisomerase III [Bordetella bronchiseptica].	29.58	683	389	21	1	629	1	645	1e-75	268
rs:WP_003296453	DNA topoisomerase III [Pseudomonas stutzeri].	29.14	676	421	19	1	638	1	656	1e-75	268
rs:WP_005566047	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	31.37	628	367	19	1	581	1	611	1e-75	267
rs:WP_025217413	DNA topoisomerase III [Mannheimia varigena].	30.73	628	385	17	1	592	1	614	1e-75	267
tr:W1K7D6_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.53	593	349	16	38	611	10	564	1e-75	268
tr:F3QN10_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.91	632	380	17	1	588	3	615	1e-75	266
rs:WP_027074724	DNA topoisomerase III [Mannheimia granulomatis].	30.73	628	385	17	1	592	1	614	1e-75	267
rs:WP_042601263	DNA topoisomerase III [Vibrio harveyi].	30.48	620	376	16	2	581	3	607	1e-75	267
rs:WP_046481894	DNA topoisomerase III [Pseudomonas veronii].	27.81	658	430	14	1	629	1	642	1e-75	267
rs:WP_032529718	DNA topoisomerase I [Bacteroides fragilis].	29.00	707	455	20	1	684	1	683	1e-75	268
tr:X2JT78_AGGAC	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.15	626	371	18	1	581	16	626	1e-75	267
sp:TOP3_PASMU	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	30.70	632	375	17	1	583	1	618	1e-75	267
rs:WP_001177802	DNA topoisomerase III [Escherichia coli].	28.53	638	414	16	1	610	1	624	1e-75	268
rs:WP_019717336	DNA topoisomerase III [Ralstonia solanacearum].	29.83	714	436	22	3	673	5	696	1e-75	271
rs:WP_025822161	DNA topoisomerase III [Shewanella marina].	30.24	635	397	16	1	598	1	626	1e-75	267
rs:WP_005552801	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	31.37	628	367	19	1	581	1	611	1e-75	267
rs:WP_035293839	DNA topoisomerase III [Actinobacillus minor].	31.58	608	370	20	1	574	1	596	1e-75	267
rs:WP_023926441	hypothetical protein [Prevotella nigrescens].	30.07	695	433	20	4	673	5	671	1e-75	268
rs:WP_033948794	DNA topoisomerase III [Pseudomonas aeruginosa].	28.88	644	409	16	1	614	1	625	1e-75	268
rs:WP_016270792	DNA topoisomerase III [Bacteroides vulgatus].	28.82	701	453	18	1	676	1	680	1e-75	268
rs:WP_027601788	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	28.22	645	415	15	1	614	1	628	1e-75	268
rs:WP_008143492	DNA topoisomerase III [Bacteroides coprophilus].	29.92	722	397	22	1	630	1	705	1e-75	269
rs:WP_038242886	DNA topoisomerase III [Virgibacillus sp. Vm-5].	31.27	630	401	17	3	615	5	619	1e-75	269
rs:WP_013903096	DNA topoisomerase III [Ramlibacter tataouinensis].	30.19	722	426	24	3	666	5	706	1e-75	273
rs:WP_045569553	DNA topoisomerase III [Vibrio sp. S234-5].	30.18	613	387	13	2	581	3	607	1e-75	267
rs:WP_005396516	DNA topoisomerase III [Vibrio alginolyticus].	30.02	613	388	13	2	581	3	607	1e-75	267
rs:WP_006743281	DNA topoisomerase III [Vibrio sp. Ex25].	30.02	613	388	13	2	581	3	607	1e-75	267
rs:WP_044782902	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.37	698	443	19	2	676	4	681	1e-75	268
rs:WP_022544106	DNA topoisomerase III [Bacillus infantis].	28.65	705	454	18	1	661	1	700	1e-75	269
rs:WP_032551967	DNA topoisomerase III [Vibrio fortis].	31.20	593	367	14	2	560	3	588	1e-75	267
rs:WP_039420015	DNA topoisomerase I [Porphyromonas gulae].	29.53	701	443	20	1	676	1	675	1e-75	268
rs:WP_022242126	DNA topoisomerase [Clostridium sp. CAG:413].	31.81	723	428	22	1	680	1	701	1e-75	268
rs:WP_014338762	DNA topoisomerase III [Pseudomonas fluorescens].	27.68	672	434	16	1	638	1	654	1e-75	267
rs:WP_019423519	DNA topoisomerase III [Paenibacillus sp. OSY-SE].	30.05	659	389	22	3	626	4	625	1e-75	268
rs:WP_035463497	DNA topoisomerase III [Lactobacillus ceti].	29.61	662	398	18	2	644	4	616	1e-75	268
rs:WP_004319201	MULTISPECIES: DNA topoisomerase I [Bacteroides].	28.95	708	454	22	1	684	1	683	1e-75	268
rs:WP_044300564	DNA topoisomerase I [Bacteroides fragilis].	28.94	705	458	18	1	684	1	683	1e-75	268
rs:WP_036685598	DNA topoisomerase III [Paenibacillus sp. MSt1].	28.83	711	420	20	3	667	4	674	1e-75	268
tr:U3U493_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.11	639	407	14	1	610	1	622	1e-75	268
rs:WP_036204086	DNA topoisomerase [Megasphaera elsdenii].	30.15	670	412	19	1	636	1	648	2e-75	268
rs:WP_027597847	DNA topoisomerase III [Pseudomonas sp. MOIL14HWK12:I2].	27.86	646	416	14	1	614	1	628	2e-75	268
rs:WP_018910191	DNA topoisomerase I [Prevotella veroralis].	30.56	697	427	19	4	673	5	671	2e-75	268
rs:WP_041454535	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	30.57	615	385	19	1	581	1	607	2e-75	267
rs:WP_004033898	DNA topoisomerase III [Clostridium sp. ASF356].	30.10	691	450	18	3	668	5	687	2e-75	268
rs:WP_033879165	DNA topoisomerase III [Escherichia coli].	27.94	637	419	14	1	610	1	624	2e-75	267
rs:WP_005430340	DNA topoisomerase [Sutterella wadsworthensis].	29.41	612	381	16	1	573	1	600	2e-75	266
rs:WP_017167698	DNA topoisomerase [Xanthomonas axonopodis].	30.20	692	414	22	1	640	1	675	2e-75	268
rs:WP_005753511	DNA topoisomerase III [Pasteurella multocida].	31.49	632	370	20	1	583	1	618	2e-75	267
rs:WP_012754023	DNA topoisomerase III [Methylobacterium extorquens].	28.93	643	421	15	2	610	4	644	2e-75	271
rs:WP_028723486	DNA topoisomerase III [Pantoea ananatis].	29.76	625	372	17	1	581	1	602	2e-75	266
rs:WP_017168798	DNA topoisomerase [Xanthomonas axonopodis].	30.10	691	416	21	1	640	1	675	2e-75	268
rs:WP_025235882	DNA topoisomerase III [Mannheimia varigena].	30.77	624	390	18	1	592	1	614	2e-75	266
rs:WP_042048532	DNA topoisomerase III [Aeromonas simiae].	30.93	611	383	18	1	581	1	602	2e-75	267
rs:WP_044111880	hypothetical protein [Porphyromonas uenonis].	31.00	713	426	23	4	682	7	687	2e-75	268
rs:WP_009229667	DNA topoisomerase I [Prevotella sp. oral taxon 317].	29.99	707	425	21	1	673	2	672	2e-75	268
rs:WP_039136943	DNA topoisomerase III, partial [Gallibacterium genomosp. 2].	30.54	609	379	17	3	581	4	598	2e-75	265
rs:WP_009125918	DNA topoisomerase I [Bacteroides fluxus].	28.43	707	459	20	1	684	1	683	2e-75	268
rs:WP_009016629	DNA topoisomerase I [Parabacteroides sp. D13].	29.60	706	450	20	1	684	1	681	2e-75	268
rs:WP_009003369	DNA topoisomerase III [Clostridium sp. D5].	28.61	699	444	19	2	671	5	677	2e-75	268
rs:WP_017161201	DNA topoisomerase [Xanthomonas axonopodis].	30.10	691	416	21	1	640	1	675	2e-75	268
tr:S0RWA0_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.51	584	349	15	41	611	3	548	2e-75	267
tr:W1GKG1_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.87	571	353	16	41	581	2	566	2e-75	266
rs:WP_018758435	hypothetical protein [Paenibacillus terrigena].	29.14	676	411	18	3	646	4	643	2e-75	268
rs:WP_032585083	MULTISPECIES: DNA topoisomerase I [Bacteroides].	28.67	701	454	18	1	676	1	680	2e-75	268
rs:WP_023564812	DNA topoisomerase III, partial [Escherichia coli].	32.44	561	338	18	1	530	1	551	2e-75	264
rs:WP_007483903	DNA topoisomerase I [Bacteroides nordii].	28.94	705	458	18	1	684	1	683	2e-75	268
rs:WP_004319756	DNA topoisomerase I [Bacteroides ovatus].	28.79	705	459	18	1	684	1	683	2e-75	268
rs:WP_016212888	DNA topoisomerase III [Parabacteroides goldsteinii].	28.39	708	460	20	1	685	1	684	2e-75	268
rs:WP_028860034	DNA topoisomerase III [Ralstonia solanacearum].	29.83	714	436	22	3	673	5	696	2e-75	271
rs:WP_039881886	DNA topoisomerase III [Marinobacter manganoxydans].	28.77	643	429	10	1	615	1	642	2e-75	268
rs:WP_032277657	DNA topoisomerase III, partial [Escherichia coli].	31.87	571	353	16	41	581	8	572	2e-75	266
tr:A0A0A3FDX4_9VIBR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.23	612	388	14	2	581	3	607	2e-75	267
rs:WP_014326230	DNA topoisomerase III [Pasteurella multocida].	31.12	633	371	19	1	583	1	618	2e-75	266
rs:WP_027252817	DNA topoisomerase III [Photobacterium halotolerans].	30.54	609	388	14	2	581	3	605	2e-75	267
rs:WP_017350143	DNA topoisomerase III [Pasteurella multocida].	31.80	632	368	20	1	583	1	618	2e-75	266
rs:WP_029484957	DNA topoisomerase III [Enterobacter mori].	28.45	682	424	17	1	641	1	659	2e-75	267
rs:WP_010803751	MULTISPECIES: DNA topoisomerase III [Parabacteroides].	28.37	712	453	18	1	684	1	683	2e-75	268
rs:WP_012723224	DNA topoisomerase III [Pseudomonas fluorescens].	28.09	680	420	17	1	638	1	653	2e-75	266
tr:M4GX47_PECCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.96	676	443	15	1	645	1	663	2e-75	267
rs:WP_045282284	DNA topoisomerase III [Enterobacter sp. 44593].	29.35	644	399	16	1	610	1	622	2e-75	267
rs:WP_005344509	DNA topoisomerase III [[Eubacterium] hallii].	31.71	659	386	21	2	627	3	630	2e-75	268
tr:C5S0M3_9PAST	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.58	608	370	20	1	574	15	610	2e-75	266
rs:WP_005723459	DNA topoisomerase III [Pasteurella multocida].	31.80	632	368	20	1	583	1	618	2e-75	266
rs:WP_038891461	DNA topoisomerase III [Vibrio campbellii].	30.23	612	388	14	2	581	3	607	2e-75	266
rs:WP_046356583	DNA topoisomerase III [Pseudoalteromonas luteoviolacea].	31.74	627	379	16	1	592	1	613	2e-75	266
rs:WP_041098558	DNA topoisomerase III [Bacillus badius].	29.56	697	463	15	3	676	4	695	2e-75	268
rs:WP_009000847	DNA topoisomerase I [Bacteroides sp. D2].	28.98	704	459	18	1	684	1	683	2e-75	268
rs:WP_022169972	DNA topoisomerase [Eubacterium hallii CAG:12].	31.71	659	386	21	2	627	3	630	2e-75	268
rs:WP_046333399	DNA topoisomerase III [Pasteurella multocida].	31.65	632	369	20	1	583	1	618	2e-75	266
rs:WP_004295480	DNA topoisomerase I [Bacteroides eggerthii].	28.95	708	454	22	1	684	1	683	2e-75	268
rs:WP_010764183	DNA topoisomerase III [Enterococcus moraviensis].	30.66	623	376	15	2	611	5	584	2e-75	267
rs:WP_005800102	DNA topoisomerase I [Bacteroides fragilis].	30.34	712	445	22	1	684	1	689	2e-75	268
rs:WP_007366532	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	30.34	712	437	26	1	684	1	681	2e-75	268
rs:WP_044135992	DNA topoisomerase I [Bacteroides fragilis].	28.94	705	458	18	1	684	1	683	2e-75	267
rs:WP_022965391	DNA topoisomerase III [Pseudomonas caeni].	30.72	625	371	18	1	581	1	607	2e-75	266
rs:WP_025247771	DNA topoisomerase III [Mannheimia varigena].	30.73	628	385	17	1	592	1	614	2e-75	266
rs:WP_042381158	DNA topoisomerase III [Geobacillus kaustophilus].	29.24	660	412	18	3	646	4	624	2e-75	268
rs:WP_021279340	DNA topoisomerase III [Mannheimia haemolytica].	29.89	629	389	18	1	592	1	614	2e-75	266
rs:WP_008141550	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	30.42	710	439	23	1	684	1	681	2e-75	267
rs:WP_012533717	DNA topoisomerase III [Aliivibrio fischeri].	30.60	621	367	15	2	574	12	616	2e-75	266
rs:WP_009601820	DNA topoisomerase III [Vibrio caribbeanicus].	31.27	614	380	12	2	581	3	608	2e-75	266
rs:WP_021979974	DNA topoisomerase III [Paraprevotella clara CAG:116].	29.04	706	456	20	1	684	1	683	2e-75	267
rs:WP_005607796	MULTISPECIES: DNA topoisomerase III [Actinobacillus].	29.72	646	402	17	1	614	1	626	2e-75	267
rs:WP_033746697	DNA topoisomerase III [Pantoea sp. NGS-ED-1003].	29.71	626	371	18	1	581	1	602	2e-75	266
rs:WP_034759989	DNA topoisomerase III [Bacillus vietnamensis].	30.86	661	387	21	3	627	5	631	2e-75	268
rs:WP_039195103	DNA topoisomerase III [Actinobacillus suis].	29.72	646	402	17	1	614	1	626	3e-75	267
rs:WP_040434002	DNA topoisomerase III [Erysipelatoclostridium ramosum].	32.55	639	376	21	3	615	5	614	3e-75	268
rs:WP_002577786	DNA topoisomerase III [[Clostridium] bolteae].	29.88	656	409	18	3	627	4	639	3e-75	268
rs:WP_037587002	DNA topoisomerase III, partial [Stenoxybacter acetivorans].	31.56	564	349	16	41	571	3	562	3e-75	265
rs:WP_029486090	DNA topoisomerase [Enterococcus gallinarum].	29.34	726	440	20	3	675	4	709	3e-75	268
rs:WP_004349950	DNA topoisomerase I [Prevotella buccalis].	29.96	701	433	20	1	673	2	672	3e-75	267
rs:WP_003498632	MULTISPECIES: DNA topoisomerase III [Clostridiales].	30.09	658	409	18	3	627	4	643	3e-75	268
rs:WP_018579558	MULTISPECIES: DNA topoisomerase III [Firmicutes].	33.72	611	325	23	1	581	1	561	3e-75	264
rs:WP_045421631	DNA topoisomerase III [Vibrio campbellii].	30.23	612	388	14	2	581	3	607	3e-75	266
tr:E1YNZ2_9PORP	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFK64041.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFK64041.1};	28.45	703	457	15	1	678	1	682	3e-75	267
rs:WP_034217778	DNA topoisomerase III, partial [Lachnospiraceae bacterium AB2028].	32.27	598	371	16	3	585	10	588	3e-75	265
rs:WP_018910666	DNA topoisomerase I [Prevotella veroralis].	30.23	698	435	19	1	673	2	672	3e-75	267
rs:WP_038167760	DNA topoisomerase III [Verrucomicrobium sp. BvORR106].	27.56	733	469	18	3	684	5	726	3e-75	271
rs:WP_021069091	transposase [Sphingobacterium paucimobilis].	30.14	710	448	18	1	676	1	696	3e-75	267
tr:D0TV73_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	29.69	650	424	13	45	676	2	636	3e-75	266
rs:WP_044321331	DNA topoisomerase III [Pseudomonas amygdali].	28.18	660	424	17	1	629	1	641	3e-75	266
rs:WP_006962977	DNA topoisomerase III [Vibrio coralliilyticus].	30.72	612	385	13	2	581	3	607	3e-75	266
rs:WP_017121484	DNA topoisomerase [Xanthomonas vasicola].	30.10	691	416	21	1	640	1	675	3e-75	267
rs:WP_034530141	DNA topoisomerase I [Parabacteroides sp. 20_3].	28.45	703	457	16	1	678	24	705	3e-75	268
rs:WP_026759425	DNA topoisomerase [Selenomonas ruminantium].	29.53	674	413	19	1	629	1	657	3e-75	270
rs:WP_034110802	DNA topoisomerase III, partial [Comamonadaceae bacterium BICA1-1].	32.29	669	377	25	3	611	8	660	3e-75	271
rs:WP_008777083	DNA topoisomerase I [Bacteroides sp. 2_2_4].	28.63	702	443	21	1	673	1	673	3e-75	267
rs:WP_010296837	DNA topoisomerase III [Clostridium senegalense].	30.91	660	394	21	3	627	5	637	3e-75	268
rs:WP_013056933	DNA topoisomerase III [Bacillus megaterium].	29.94	658	406	17	3	646	4	620	3e-75	267
tr:J6Y259_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.59	595	366	14	28	611	6	564	3e-75	266
rs:WP_027697374	DNA topoisomerase III [Vibrio litoralis].	30.92	621	386	13	1	587	2	613	3e-75	266
rs:WP_005432974	DNA topoisomerase III [Vibrio campbellii].	29.79	621	379	14	2	581	3	607	3e-75	266
rs:WP_037288732	DNA topoisomerase III [Saccharibacillus sacchari].	28.82	753	452	21	1	681	1	741	3e-75	268
rs:WP_034307594	DNA topoisomerase III [Bacillus simplex].	30.93	734	439	23	1	686	1	714	3e-75	268
rs:WP_032567475	DNA topoisomerase I, partial [Bacteroides fragilis].	30.45	683	422	22	29	684	12	668	3e-75	267
rs:WP_046524222	DNA topoisomerase III [Bacillus sp. SA2-6].	28.14	725	455	19	1	677	1	707	3e-75	268
rs:WP_009724609	DNA topoisomerase III [Halomonas sp. TD01].	29.60	642	400	18	1	612	1	620	3e-75	266
tr:A0A0D8YIF7_BACLI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KJH56470.1};	30.37	708	424	23	3	679	4	673	3e-75	269
rs:WP_005794081	DNA topoisomerase I [Bacteroides fragilis].	29.96	711	441	22	1	684	1	681	3e-75	267
rs:WP_004303817	DNA topoisomerase I [Bacteroides ovatus].	28.43	707	459	20	1	684	1	683	3e-75	267
rs:WP_000108742	MULTISPECIES: hypothetical protein [Lactobacillales].	30.07	725	436	20	3	675	4	709	3e-75	268
rs:WP_005867781	DNA topoisomerase I [Parabacteroides distasonis].	30.10	711	440	22	1	684	1	681	3e-75	267
rs:WP_012128555	DNA topoisomerase III [Vibrio campbellii].	30.23	612	388	14	2	581	3	607	3e-75	266
rs:WP_027130404	DNA topoisomerase III [Gemella cuniculi].	31.03	651	381	19	3	625	4	614	3e-75	267
rs:WP_015461373	MULTISPECIES: DNA topoisomerase III [Edwardsiella].	29.32	614	389	16	1	581	1	602	3e-75	266
rs:WP_029321603	DNA topoisomerase III [Bacillus sp. RP1137].	29.94	658	406	17	3	646	4	620	3e-75	267
rs:WP_009132146	DNA topoisomerase III [Bacteroides oleiciplenus].	28.43	707	459	20	1	684	1	683	3e-75	267
rs:WP_005368918	DNA topoisomerase III [Photobacterium angustum].	30.85	603	380	15	2	574	3	598	3e-75	266
rs:WP_011609880	DNA topoisomerase III [Histophilus somni].	29.77	645	401	17	1	614	1	624	3e-75	266
rs:WP_039555145	DNA topoisomerase III [Vibrio vulnificus].	30.34	669	403	20	2	631	3	647	3e-75	266
rs:WP_024535808	DNA topoisomerase III [Sporosarcina sp. EUR3 2.2.2].	30.13	707	457	18	3	681	4	701	3e-75	267
rs:WP_025585606	DNA topoisomerase III [Cupriavidus taiwanensis].	29.43	717	441	22	3	677	5	698	3e-75	271
rs:WP_027705174	DNA topoisomerase III [Zymobacter palmae].	31.13	620	375	18	1	581	1	607	3e-75	266
rs:WP_018005000	DNA topoisomerase III [Cupriavidus taiwanensis].	29.43	717	441	22	3	677	5	698	3e-75	271
rs:WP_039611528	DNA topoisomerase III [Pseudoalteromonas luteoviolacea].	32.10	623	382	16	1	592	1	613	3e-75	266
rs:WP_040841233	DNA topoisomerase III, partial [Thiothrix nivea].	29.19	620	392	15	1	581	1	612	4e-75	265
rs:WP_001422194	DNA topoisomerase III family protein [Escherichia coli].	28.73	637	414	16	1	610	1	624	4e-75	266
rs:WP_012277719	DNA topoisomerase III [Shewanella halifaxensis].	28.95	677	427	17	1	635	1	665	4e-75	266
rs:WP_027374792	DNA topoisomerase I [Chryseobacterium sp. UNC8MFCol].	28.43	707	456	20	1	682	1	682	4e-75	267
rs:WP_005419931	DNA topoisomerase III [Aliivibrio fischeri].	30.60	621	367	16	2	574	12	616	4e-75	266
rs:WP_033694064	DNA topoisomerase III [Bacillus cereus].	31.01	703	438	21	2	679	4	684	4e-75	267
rs:WP_005514989	DNA topoisomerase III [Vibrio mimicus].	31.25	624	366	17	2	581	3	607	4e-75	266
rs:WP_011888497	DNA topoisomerase III [Geobacillus thermodenitrificans].	30.83	707	454	18	1	679	1	700	4e-75	267
rs:WP_016726768	DNA topoisomerase III [Ralstonia solanacearum].	29.83	714	436	22	3	673	5	696	4e-75	270
rs:WP_016722609	DNA topoisomerase III [Ralstonia solanacearum].	29.83	714	436	22	3	673	5	696	4e-75	270
rs:WP_042410060	DNA topoisomerase III [Geobacillus caldoxylosilyticus].	30.88	706	455	18	1	679	1	700	4e-75	267
rs:WP_006835528	DNA topoisomerase III [Bacillus sp. SG-1].	29.61	726	449	23	1	681	1	709	4e-75	267
rs:WP_025571064	DNA topoisomerase III, partial [Flavobacterium sp. JGI 0001001-D01].	31.28	649	376	22	54	661	4	623	4e-75	267
rs:WP_003507970	DNA topoisomerase III [[Clostridium] symbiosum].	29.94	658	410	18	3	627	4	643	4e-75	268
rs:WP_016978867	DNA topoisomerase III [Pseudomonas fluorescens].	27.96	658	429	15	1	629	1	642	4e-75	266
rs:WP_007207501	DNA topoisomerase III [Enterococcus italicus].	29.53	657	405	17	2	644	3	615	4e-75	267
rs:WP_032846518	MULTISPECIES: DNA topoisomerase I [Bacteroides].	28.86	700	444	21	1	673	1	673	4e-75	267
rs:WP_024893297	DNA topoisomerase III [Acidithiobacillus thiooxidans].	29.15	693	412	20	1	640	1	667	4e-75	266
tr:C6IR36_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EES67056.2};	28.67	701	454	18	1	676	23	702	4e-75	267
rs:WP_004435076	DNA topoisomerase III [Bacillus methanolicus].	29.04	737	460	19	1	686	1	725	4e-75	268
tr:B0N116_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.55	639	376	21	3	615	16	625	4e-75	268
rs:WP_008881726	DNA topoisomerase III [Geobacillus sp. G11MC16].	30.83	707	454	18	1	679	1	700	4e-75	267
rs:WP_015879466	DNA topoisomerase III [Tolumonas auensis].	29.14	676	421	19	1	638	1	656	4e-75	266
rs:WP_014862450	DNA topoisomerase [Enterococcus faecalis].	29.61	726	438	21	3	675	4	709	4e-75	267
rs:WP_034265868	DNA topoisomerase III [Bacillus sp. Aph1].	29.94	658	406	17	3	646	4	620	4e-75	267
rs:WP_031598690	DNA topoisomerase III [Ferrovum myxofaciens].	29.01	679	420	21	1	645	1	651	4e-75	267
rs:WP_002589689	MULTISPECIES: DNA topoisomerase III [Clostridiales].	29.88	656	409	18	3	627	4	639	4e-75	268
rs:WP_014699279	DNA topoisomerase [Pectobacterium sp. SCC3193].	28.73	644	410	15	1	614	1	625	4e-75	266
rs:WP_009012816	DNA topoisomerase I [Prevotella sp. C561].	30.59	693	434	18	3	673	4	671	4e-75	266
rs:WP_004352634	DNA topoisomerase I [Prevotella denticola].	30.99	697	424	21	4	673	5	671	4e-75	266
rs:WP_024733367	DNA topoisomerase III [Clostridiales bacterium VE202-14].	32.20	649	382	20	3	627	4	618	4e-75	267
rs:WP_010992404	DNA topoisomerase I [Bacteroides fragilis].	28.90	706	457	19	1	684	1	683	4e-75	266
rs:WP_012301124	TrsI protein [Geobacillus stearothermophilus].	30.83	707	454	18	1	679	1	700	4e-75	267
rs:WP_008766823	DNA topoisomerase I [Bacteroides sp. 1_1_6].	28.90	706	457	19	1	684	1	683	4e-75	266
rs:WP_012354342	DNA topoisomerase III [Cupriavidus taiwanensis].	29.43	717	441	22	3	677	5	698	4e-75	270
rs:WP_021555971	hypothetical protein [Escherichia coli].	29.06	640	408	19	1	610	1	624	5e-75	266
rs:WP_012457618	DNA topoisomerase I [Porphyromonas gingivalis].	29.53	701	443	19	1	676	1	675	5e-75	266
rs:WP_014668193	DNA topoisomerase III [Pasteurella multocida].	31.12	633	371	19	1	583	1	618	5e-75	266
rs:WP_034546490	DNA topoisomerase III [Carnobacterium alterfunditum].	29.49	712	459	17	1	682	3	701	5e-75	267
rs:WP_010763001	DNA topoisomerase III [Enterococcus haemoperoxidus].	30.30	660	396	18	2	644	5	617	5e-75	266
rs:WP_012139595	DNA topoisomerase III [Marinobacter lipolyticus].	29.41	646	414	14	1	614	1	636	5e-75	267
rs:WP_019429929	DNA topoisomerase III [Limnohabitans sp. Rim47].	29.50	722	434	24	3	666	4	708	5e-75	271
rs:WP_039432611	DNA topoisomerase III [Vibrio navarrensis].	30.18	613	387	14	2	581	3	607	5e-75	266
rs:WP_025836956	DNA topoisomerase I [Prevotella scopos].	30.81	701	420	22	4	673	5	671	5e-75	266
rs:WP_036856717	DNA topoisomerase I [Prevotella amnii].	30.77	702	426	21	1	673	2	672	5e-75	266
rs:WP_023263469	DNA topoisomerase III [Cupriavidus sp. HPC(L)].	29.71	717	437	23	3	677	5	696	5e-75	270
rs:WP_042232421	DNA topoisomerase III [Paenibacillus sp. FSL R5-0912].	30.61	637	385	18	3	615	4	607	5e-75	267
rs:WP_005490789	DNA topoisomerase III [Pseudoalteromonas luteoviolacea].	31.13	620	378	16	1	584	1	607	5e-75	265
rs:WP_016177605	DNA topoisomerase III [Enterococcus durans].	29.93	725	437	20	3	675	4	709	5e-75	267
rs:WP_005532611	DNA topoisomerase III [Vibrio campbellii].	30.46	614	384	16	2	581	3	607	5e-75	266
rs:WP_010759745	DNA topoisomerase III [Enterococcus pallens].	29.53	657	404	16	2	644	3	614	5e-75	266
rs:WP_006678765	DNA topoisomerase III [Paenibacillus dendritiformis].	30.40	671	403	21	3	646	4	637	5e-75	267
rs:WP_018968449	DNA topoisomerase I [Prevotella loescheii].	30.29	700	431	22	1	673	2	671	5e-75	266
rs:WP_017169969	DNA topoisomerase [Xanthomonas axonopodis].	30.10	691	416	21	1	640	1	675	5e-75	266
rs:WP_011000033	DNA topoisomerase III [Ralstonia solanacearum].	29.83	714	436	22	3	673	5	696	5e-75	270
rs:WP_028413452	DNA topoisomerase III [Bacillus sp. 278922_107].	29.94	658	406	17	3	646	4	620	5e-75	266
rs:WP_021646279	DNA topoisomerase [Bacteroides pyogenes].	30.62	712	443	25	1	684	1	689	5e-75	267
rs:WP_024738311	DNA topoisomerase III [Clostridiales bacterium VE202-16].	30.09	658	409	18	3	627	4	643	5e-75	267
rs:WP_014593831	DNA topoisomerase III [Pantoea ananatis].	29.60	625	373	17	1	581	1	602	5e-75	265
rs:WP_002509280	DNA topoisomerase III [Staphylococcus arlettae].	30.41	638	387	16	3	615	4	609	5e-75	267
rs:WP_045419892	DNA topoisomerase III [Vibrio jasicida].	30.65	620	375	16	2	581	3	607	5e-75	266
rs:WP_013025979	DNA topoisomerase III [Pantoea ananatis].	29.71	626	371	18	1	581	1	602	5e-75	265
rs:WP_010644027	DNA topoisomerase III [Vibrio campbellii].	30.07	612	389	14	2	581	3	607	5e-75	265
rs:WP_000088633	DNA topoisomerase III [Vibrio mimicus].	30.97	620	373	16	2	581	3	607	5e-75	265
rs:WP_045453629	DNA topoisomerase III [Vibrio campbellii].	30.23	612	388	14	2	581	3	607	5e-75	265
rs:WP_033578902	DNA topoisomerase III [Bacillus aryabhattai].	29.94	658	406	17	3	646	4	620	5e-75	266
rs:WP_014460219	DNA topoisomerase III [Bacillus megaterium].	29.85	660	404	17	3	646	4	620	6e-75	266
rs:WP_007485367	MULTISPECIES: DNA topoisomerase I [Bacteroides].	28.74	696	450	20	1	673	1	673	6e-75	266
rs:WP_018919957	DNA topoisomerase I [Prevotella oris].	30.43	700	428	22	3	673	4	673	6e-75	266
rs:WP_045387311	DNA topoisomerase III [Vibrio rotiferianus].	29.69	613	390	13	2	581	3	607	6e-75	265
rs:WP_009698532	DNA topoisomerase III [Vibrio sp. HENC-01].	30.56	612	386	14	2	581	3	607	6e-75	265
rs:WP_025342567	DNA topoisomerase III [Mannheimia varigena].	30.89	628	384	18	1	592	1	614	6e-75	265
rs:WP_018968363	DNA topoisomerase I [Prevotella loescheii].	30.88	693	430	21	4	673	5	671	6e-75	266
rs:WP_002567851	DNA topoisomerase III [[Clostridium] bolteae].	29.73	656	410	18	3	627	4	639	6e-75	267
rs:WP_039325610	DNA topoisomerase III [Pectobacterium betavasculorum].	28.86	641	413	15	1	614	1	625	6e-75	266
rs:WP_029486035	DNA topoisomerase [Enterococcus gallinarum].	29.61	726	438	21	3	675	4	709	6e-75	267
rs:WP_013265186	DNA topoisomerase I [Prevotella melaninogenica].	29.75	706	423	21	4	673	5	673	6e-75	266
rs:WP_029486302	DNA topoisomerase III [Enterococcus gallinarum].	29.35	627	384	15	2	614	3	584	6e-75	266
rs:WP_025039084	MULTISPECIES: DNA topoisomerase III [Geobacillus].	29.71	663	405	20	3	646	4	624	6e-75	266
tr:G6YQR7_9ALTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.77	643	429	10	1	615	53	694	6e-75	268
rs:WP_022623227	DNA topoisomerase III [Pantoea ananatis].	29.60	625	373	17	1	581	1	602	6e-75	265
tr:H0DFI8_9STAP	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.08	635	393	15	3	615	4	609	6e-75	266
rs:WP_030072583	DNA topoisomerase III [Halomonas alkaliantarctica].	29.89	629	395	17	1	602	1	610	6e-75	265
rs:WP_044976020	DNA topoisomerase III, partial [[Eubacterium] cellulosolvens].	30.39	622	371	16	1	585	1	597	7e-75	264
rs:WP_043294193	DNA topoisomerase III [Burkholderia pseudomallei].	29.45	618	395	16	1	587	1	608	7e-75	266
rs:WP_041154903	DNA topoisomerase III [Vibrio mytili].	29.90	612	390	13	2	581	3	607	7e-75	265
rs:WP_008124769	DNA topoisomerase I [Prevotella timonensis].	30.07	705	427	21	1	673	2	672	7e-75	266
rs:WP_032597189	DNA topoisomerase I [Bacteroides fragilis].	28.43	707	459	20	1	684	1	683	7e-75	266
rs:WP_035664890	DNA topoisomerase III [Bacillus akibai].	29.73	730	450	21	1	683	1	714	7e-75	266
rs:WP_009355184	DNA topoisomerase III [Vibrio sp. RC341].	30.93	624	368	16	2	581	3	607	7e-75	265
rs:WP_034490094	DNA topoisomerase III [Butyrivibrio fibrisolvens].	30.71	622	370	17	1	585	1	598	7e-75	265
rs:WP_010750414	DNA topoisomerase III, partial [Enterococcus villorum].	30.86	580	358	13	41	611	3	548	7e-75	265
tr:A0A098EIM9_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.49	716	455	19	3	681	4	699	7e-75	266
rs:WP_032600052	DNA topoisomerase I [Bacteroides fragilis].	28.74	696	450	20	1	673	1	673	7e-75	266
rs:WP_020300890	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	27.55	657	433	15	1	629	1	642	7e-75	265
rs:WP_011334398	DNA topoisomerase III [Pseudomonas fluorescens].	28.05	663	422	17	1	629	1	642	7e-75	265
rs:WP_044340829	DNA topoisomerase III [Pseudomonas oryzihabitans].	27.71	646	417	14	1	614	1	628	7e-75	266
rs:WP_009228981	DNA topoisomerase I [Prevotella sp. oral taxon 299].	30.22	695	432	19	4	673	5	671	7e-75	266
rs:WP_007656370	DNA topoisomerase I [Parabacteroides goldsteinii].	29.61	716	437	22	1	684	1	681	7e-75	266
rs:WP_041902077	DNA topoisomerase III [Bacillus thermoamylovorans].	28.59	717	468	18	1	681	1	709	7e-75	266
rs:WP_002321930	DNA topoisomerase III [Enterococcus faecium].	30.06	632	387	16	28	644	6	597	7e-75	266
rs:WP_036978385	DNA topoisomerase III [Pseudobutyrivibrio sp. MD2005].	30.88	625	364	18	1	585	1	597	7e-75	265
gp:FP929058_263	DNA topoisomerase III, bacteria and conjugative plasmid [Enterococcus sp. 7L76]	29.78	722	442	21	3	675	4	709	8e-75	266
tr:A0A0D0Q8E3_9BACI	SubName: Full=Anoxybacillus thermarum strain AF/04 contig000028, whole genome shotgun sequence {ECO:0000313|EMBL:KIQ94273.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIQ94273.1};	30.08	665	397	20	3	646	5	622	8e-75	266
rs:WP_009257548	DNA topoisomerase III [Lachnospiraceae bacterium 7_1_58FAA].	29.19	651	417	15	3	627	5	637	8e-75	267
rs:WP_038881887	DNA topoisomerase III [Vibrio jasicida].	30.56	612	386	14	2	581	3	607	8e-75	265
rs:WP_004364408	DNA topoisomerase III [Prevotella nigrescens].	30.69	694	432	20	3	673	4	671	8e-75	266
rs:WP_033186461	DNA topoisomerase III [Pseudoalteromonas sp. PLSV].	30.07	612	389	12	1	581	1	604	8e-75	265
rs:WP_034255094	DNA topoisomerase III [Bifidobacterium kashiwanohense].	27.61	746	452	23	1	679	1	725	8e-75	267
rs:WP_026073519	DNA topoisomerase III [Bacillus massiliosenegalensis].	29.79	725	454	23	1	682	1	713	8e-75	266
rs:WP_003604286	DNA topoisomerase III [Methylobacterium extorquens].	28.93	643	421	15	2	610	4	644	8e-75	270
rs:WP_043966410	DNA topoisomerase III [Anoxybacillus thermarum].	30.08	665	397	20	3	646	4	621	8e-75	266
tr:I5AS62_EUBCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.60	621	371	16	1	585	1	597	8e-75	265
tr:N9TX52_9GAMM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.39	612	385	18	1	581	1	602	8e-75	265
tr:A0A085IJE3_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.44	588	370	13	1	559	1	578	8e-75	264
rs:WP_002339809	DNA topoisomerase III [Enterococcus faecium].	30.07	725	436	20	3	675	4	709	8e-75	266
rs:WP_043597926	DNA topoisomerase III [Aeromonas diversa].	30.39	612	385	18	1	581	1	602	9e-75	265
rs:WP_027979348	DNA topoisomerase III [gamma proteobacterium L18].	27.29	656	435	13	1	629	1	641	9e-75	265
rs:WP_034652787	DNA topoisomerase III [Bacillus megaterium].	29.77	729	435	22	1	675	1	706	9e-75	266
rs:WP_031834541	DNA topoisomerase III, partial [Staphylococcus aureus].	32.67	603	357	17	36	615	2	578	9e-75	266
rs:WP_021580322	hypothetical protein [Escherichia coli].	29.08	643	404	20	1	610	1	624	9e-75	265
rs:WP_033539187	DNA topoisomerase III [Shewanella sp. ECSMB14101].	31.13	636	376	19	1	589	1	621	9e-75	266
rs:WP_004563798	DNA topoisomerase III [Lactobacillus salivarius].	30.86	661	391	18	2	644	3	615	9e-75	266
tr:D2YND5_VIBMI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.97	620	373	16	2	581	6	610	9e-75	265
rs:WP_031868422	DNA topoisomerase III, partial [Staphylococcus aureus].	32.67	603	357	17	36	615	1	577	1e-74	265
rs:WP_034860927	DNA topoisomerase III [Enterococcus faecalis].	31.68	584	347	13	41	611	1	545	1e-74	265
rs:WP_022381016	DNA topoisomerase [Ruminococcus sp. CAG:9].	31.05	657	404	18	3	627	4	643	1e-74	266
rs:WP_025580044	DNA topoisomerase III [Blautia wexlerae].	31.05	657	404	18	3	627	4	643	1e-74	266
rs:WP_029570080	DNA topoisomerase III [Pantoea ananatis].	29.44	625	374	17	1	581	1	602	1e-74	265
rs:WP_032944513	DNA topoisomerase I [Bacteroides vulgatus].	28.12	697	463	14	1	676	1	680	1e-74	266
rs:WP_014701085	DNA topoisomerase [Pectobacterium sp. SCC3193].	27.66	676	445	15	1	645	1	663	1e-74	265
rs:WP_000088632	MULTISPECIES: DNA topoisomerase III [Vibrio].	30.97	620	373	16	2	581	3	607	1e-74	265
rs:WP_008982916	DNA topoisomerase III [Ruminococcaceae bacterium D16].	28.61	699	444	19	2	671	5	677	1e-74	266
rs:WP_046874516	DNA topoisomerase III [Vibrio alginolyticus].	29.85	613	389	13	2	581	3	607	1e-74	265
rs:WP_046519398	DNA topoisomerase III [Rheinheimera sp. IITR-13].	30.20	596	369	14	1	560	1	585	1e-74	265
rs:WP_044628054	DNA topoisomerase III [Halomonas meridiana].	29.08	619	406	12	1	597	1	608	1e-74	265
rs:WP_008999438	DNA topoisomerase I [Bacteroides sp. D2].	30.06	702	451	20	1	680	1	684	1e-74	266
rs:WP_038699441	DNA topoisomerase I [Sphingobacterium sp. ML3W].	31.45	709	428	25	1	679	1	681	1e-74	266
rs:WP_039694986	DNA topoisomerase III [Dickeya solani].	29.76	662	415	19	1	629	1	645	1e-74	265
rs:WP_005523705	DNA topoisomerase III [Vibrio mimicus].	31.29	620	371	17	2	581	3	607	1e-74	265
rs:WP_016359545	DNA topoisomerase III [Gemella sanguinis].	31.57	586	368	14	3	577	4	567	1e-74	265
tr:J6LFB8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.06	632	387	16	28	644	6	597	1e-74	265
rs:WP_005593919	DNA topoisomerase III [Vibrio scophthalmi].	31.44	598	353	18	2	558	3	584	1e-74	265
rs:WP_021458968	DNA topoisomerase III [Staphylococcus sp. EGD-HP3].	30.25	638	388	16	3	615	4	609	1e-74	266
rs:WP_045377329	DNA topoisomerase III [Vibrio campbellii].	30.23	612	388	14	2	581	3	607	1e-74	265
rs:WP_045369398	DNA topoisomerase III [Vibrio campbellii].	30.07	612	389	14	2	581	3	607	1e-74	265
rs:WP_019935838	DNA topoisomerase III [Oceanimonas smirnovii].	29.84	620	383	15	1	581	1	607	1e-74	264
rs:WP_032575783	DNA topoisomerase I [Bacteroides fragilis].	30.01	713	446	22	1	684	1	689	1e-74	266
rs:WP_016428507	DNA topoisomerase III [Paenisporosarcina sp. HGH0030].	29.83	704	463	18	3	681	4	701	1e-74	266
rs:WP_010449456	DNA topoisomerase III [Vibrio rotiferianus].	30.23	612	388	14	2	581	3	607	1e-74	265
rs:WP_007135634	DNA topoisomerase I [Prevotella salivae].	29.97	714	419	22	3	673	4	679	1e-74	265
rs:WP_004437152	DNA topoisomerase III [Bacillus methanolicus].	32.13	607	364	14	1	573	1	593	1e-74	266
rs:WP_042200915	DNA topoisomerase III [Paenibacillus sp. G4].	29.36	637	393	16	3	615	4	607	1e-74	266
tr:S4DV85_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.06	632	387	16	28	644	6	597	1e-74	265
rs:WP_044269281	DNA topoisomerase III [Pseudomonas fluorescens].	27.10	668	442	15	1	638	1	653	1e-74	265
rs:WP_042133389	DNA topoisomerase III [Paenibacillus sp. FSL P4-0081].	30.46	637	386	17	3	615	4	607	1e-74	266
rs:WP_012025057	DNA topoisomerase [Flavobacterium johnsoniae].	29.77	702	436	20	1	673	1	674	1e-74	265
rs:WP_043893430	DNA topoisomerase III, partial [Osedax symbiont Rs2].	30.37	619	385	13	1	584	1	608	1e-74	263
rs:WP_005966930	MULTISPECIES: DNA topoisomerase III [Pectobacterium].	28.71	641	414	15	1	614	1	625	1e-74	265
rs:WP_028977379	DNA topoisomerase III [Sporolactobacillus terrae].	29.24	660	414	18	3	646	5	627	1e-74	265
rs:WP_039503344	DNA topoisomerase III [Pectobacterium carotovorum].	29.06	640	413	15	1	614	1	625	1e-74	265
rs:WP_045405705	DNA topoisomerase III [Vibrio jasicida].	30.39	612	387	14	2	581	3	607	1e-74	265
rs:WP_005498870	DNA topoisomerase III [Shewanella benthica].	30.78	627	376	15	1	581	1	615	1e-74	264
tr:S4EWF5_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.06	632	387	16	28	644	6	597	1e-74	265
rs:WP_021018801	DNA topoisomerase III [Vibrio gazogenes].	29.84	630	391	15	2	599	3	613	1e-74	264
rs:WP_028897907	DNA topoisomerase I [Prevotella sp. HUN102].	29.21	712	447	21	1	684	1	683	1e-74	265
tr:I3BZ80_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.03	620	393	15	1	581	12	623	1e-74	264
rs:WP_028255426	DNA topoisomerase [Veillonella magna].	28.53	715	418	19	1	629	1	708	1e-74	267
rs:WP_007851815	MULTISPECIES: DNA topoisomerase I [Bacteroides].	28.51	712	452	21	1	684	1	683	1e-74	265
rs:WP_039372716	DNA topoisomerase I [Chryseobacterium taiwanense].	29.91	702	435	19	1	673	1	674	1e-74	265
rs:WP_042133161	DNA topoisomerase III [Pseudomonas oryzihabitans].	27.71	646	417	14	1	614	1	628	1e-74	265
rs:WP_011108225	DNA topoisomerase III [Bacteroides thetaiotaomicron].	28.74	696	450	20	1	673	1	673	2e-74	265
rs:WP_039594020	DNA topoisomerase III [Pseudomonas frederiksbergensis].	28.43	686	431	19	1	646	1	666	2e-74	265
rs:WP_027912503	DNA topoisomerase III [Pseudomonas sp. URIL14HWK12:I7].	27.61	670	436	16	1	638	1	653	2e-74	264
rs:WP_042337355	hypothetical protein [Burkholderia ferrariae].	28.48	653	419	17	1	614	1	644	2e-74	265
rs:WP_042606006	DNA topoisomerase III [Vibrio harveyi].	30.48	620	376	16	2	581	3	607	2e-74	264
rs:WP_005701059	DNA topoisomerase III [Aggregatibacter aphrophilus].	31.56	621	369	18	1	581	1	605	2e-74	264
rs:WP_025002755	DNA topoisomerase I [Prevotella dentasini].	29.78	742	442	24	1	684	1	721	2e-74	266
rs:WP_043982332	DNA topoisomerase III [Bacillus aryabhattai].	29.79	658	407	17	3	646	4	620	2e-74	265
rs:WP_010731398	DNA topoisomerase III [Enterococcus faecium].	29.20	726	441	20	3	675	4	709	2e-74	266
rs:WP_032092263	DNA topoisomerase III [Necropsobacter rosorum].	30.91	618	376	18	1	581	1	604	2e-74	264
rs:WP_013145350	DNA topoisomerase III [Geobacillus sp. C56-T3].	29.39	660	411	18	3	646	4	624	2e-74	265
rs:WP_018109310	DNA topoisomerase I [Bacteroides propionicifaciens].	30.00	710	416	24	3	673	4	671	2e-74	265
rs:WP_038065733	hypothetical protein, partial [Thermodesulfovibrio thiophilus].	30.94	598	365	14	3	566	4	587	2e-74	263
rs:WP_033659502	MULTISPECIES: DNA topoisomerase III [Enterococcus].	29.97	664	393	19	2	644	5	617	2e-74	265
rs:WP_016764011	DNA topoisomerase III [Bacillus megaterium].	29.79	658	407	17	3	646	4	620	2e-74	265
rs:WP_009387842	DNA topoisomerase III [Vibrio sp. N418].	31.61	598	352	19	2	558	3	584	2e-74	264
rs:WP_036617832	DNA topoisomerase I [Parabacteroides distasonis].	28.86	700	444	23	1	673	1	673	2e-74	265
rs:WP_015594677	DNA topoisomerase III [Bacillus sp. 1NLA3E].	29.77	739	443	22	1	687	1	715	2e-74	266
rs:WP_003830724	DNA topoisomerase III [Bifidobacterium breve].	28.07	748	446	24	1	679	1	725	2e-74	266
tr:J8WAQ0_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.95	631	389	16	28	644	6	597	2e-74	265
rs:WP_039551814	DNA topoisomerase III [Pectobacterium carotovorum].	28.71	641	414	15	1	614	1	625	2e-74	265
rs:WP_029790477	DNA topoisomerase III [Vibrio harveyi].	30.39	612	387	14	2	581	3	607	2e-74	264
rs:WP_029655590	DNA topoisomerase III [Marinobacter daepoensis].	30.01	673	410	19	1	630	1	655	2e-74	266
rs:WP_015396725	DNA topoisomerase III [Candidatus Kinetoplastibacterium oncopeltii].	32.02	737	406	29	2	680	4	703	2e-74	268
rs:WP_044545505	DNA topoisomerase I [Parabacteroides distasonis].	29.80	708	448	23	1	684	1	683	2e-74	265
rs:WP_000197437	DNA topoisomerase III [Vibrio cholerae].	30.65	620	375	15	2	581	3	607	2e-74	264
rs:WP_003410932	DNA topoisomerase III [Pseudomonas syringae].	28.05	663	422	16	1	629	1	642	2e-74	264
rs:WP_043981980	DNA topoisomerase III [Bacillus aryabhattai].	29.63	729	436	22	1	675	1	706	2e-74	265
rs:WP_039660108	DNA topoisomerase III [Pantoea sp. MBLJ3].	30.31	617	380	17	1	579	1	605	2e-74	264
rs:WP_002381707	DNA topoisomerase III [Enterococcus faecalis].	29.97	664	393	19	2	644	5	617	2e-74	265
rs:WP_021704335	DNA topoisomerase III [Vibrio proteolyticus].	29.90	622	377	14	2	581	3	607	2e-74	264
rs:WP_002372058	DNA topoisomerase III [Enterococcus faecalis].	29.97	664	393	19	2	644	5	617	2e-74	265
rs:WP_016662014	DNA topoisomerase III [Bacteroides stercoris].	28.37	698	450	20	1	673	1	673	2e-74	265
rs:WP_036378381	DNA topoisomerase [Mitsuokella jalaludinii].	27.88	721	446	20	1	669	1	699	2e-74	268
rs:WP_005600974	DNA topoisomerase III [Actinobacillus pleuropneumoniae].	30.93	637	399	17	1	606	1	627	2e-74	263
rs:WP_020425541	DNA topoisomerase III [Paenibacillus riograndensis].	30.02	643	381	18	3	615	4	607	2e-74	265
rs:WP_035620641	DNA topoisomerase I [Flavobacterium hydatis].	30.17	706	434	22	1	676	1	677	2e-74	265
rs:WP_043921484	DNA topoisomerase III, partial [Paenibacillus polymyxa].	32.52	575	332	15	40	574	41	599	2e-74	263
rs:WP_034914838	DNA topoisomerase III, partial [Gilliamella apicola].	30.71	622	377	18	2	581	8	617	2e-74	263
rs:WP_039198970	DNA topoisomerase III [Actinobacillus equuli].	30.71	648	386	19	1	606	1	627	2e-74	263
rs:WP_002340969	DNA topoisomerase III, partial [Enterococcus faecium].	30.98	581	356	13	41	611	3	548	2e-74	264
rs:WP_043070206	DNA topoisomerase III [Aneurinibacillus migulanus].	28.93	674	409	21	3	646	4	637	2e-74	265
rs:WP_012142005	DNA topoisomerase III [Shewanella sediminis].	30.40	648	395	16	1	601	1	639	2e-74	265
rs:WP_001401071	DNA topoisomerase III family protein [Escherichia coli].	28.68	638	413	17	1	610	1	624	2e-74	264
rs:WP_008783346	DNA topoisomerase III [Bifidobacterium sp. 12_1_47BFAA].	27.48	746	453	22	1	679	1	725	2e-74	266
rs:WP_007019943	DNA topoisomerase III [Neptuniibacter caesariensis].	30.50	623	387	17	1	589	1	611	2e-74	263
rs:WP_042994218	DNA topoisomerase I [Bacteroides fragilis].	29.20	709	451	22	1	684	1	683	2e-74	265
tr:A0A0C8Q0Q4_SALTI	SubName: Full=TopB_1 protein {ECO:0000313|EMBL:CET05391.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CET05391.1};	28.68	638	413	17	1	610	1	624	2e-74	264
rs:WP_019276521	DNA topoisomerase III [Vibrio coralliilyticus].	30.72	612	385	13	2	581	3	607	2e-74	264
rs:WP_045289425	DNA topoisomerase III [Bacillus aryabhattai].	29.63	729	436	22	1	675	1	706	2e-74	265
rs:WP_008812062	DNA topoisomerase III [Burkholderiales bacterium 1_1_47].	30.23	622	386	15	1	583	1	613	2e-74	263
rs:WP_007486318	DNA topoisomerase I [Bacteroides nordii].	28.37	712	453	21	1	684	1	683	2e-74	265
rs:WP_045397957	DNA topoisomerase III [Vibrio sp. 090810a].	29.95	621	378	14	2	581	3	607	2e-74	264
rs:WP_032468723	DNA topoisomerase III [Vibrio mimicus].	30.81	620	374	16	2	581	3	607	2e-74	263
rs:WP_033626659	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	2e-74	265
rs:WP_032854693	MULTISPECIES: DNA topoisomerase I [Bacteroides].	28.51	712	452	21	1	684	1	683	2e-74	265
rs:WP_007114003	DNA topoisomerase III [Halomonas boliviensis].	29.51	627	400	15	1	602	1	610	2e-74	263
rs:WP_029541017	DNA topoisomerase [Selenomonas ruminantium].	30.24	678	403	24	1	629	1	657	2e-74	267
rs:WP_033591622	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	3e-74	265
rs:WP_002369154	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	3e-74	265
rs:WP_010715326	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	3e-74	265
rs:WP_025022469	DNA topoisomerase III [Lactobacillus hayakitensis].	30.57	664	388	21	2	644	3	614	3e-74	265
rs:WP_038485011	DNA topoisomerase III [Halomonas campaniensis].	30.55	586	365	16	1	560	1	570	3e-74	263
rs:WP_016763797	DNA topoisomerase III [Bacillus megaterium].	29.63	729	436	22	1	675	1	706	3e-74	265
rs:WP_019542902	hypothetical protein [Selenomonas bovis].	28.51	677	432	17	2	640	3	665	3e-74	264
rs:WP_028413674	DNA topoisomerase III [Bacillus sp. 278922_107].	29.63	729	436	22	1	675	1	706	3e-74	265
rs:WP_007665500	DNA topoisomerase I [Bacteroides intestinalis].	29.32	706	454	20	1	684	1	683	3e-74	265
rs:WP_012848346	DNA topoisomerase III [Edwardsiella tarda].	29.48	614	388	17	1	581	1	602	3e-74	263
rs:WP_015007093	MULTISPECIES: DNA topoisomerase [Lactobacillales].	30.50	741	424	26	3	676	4	720	3e-74	265
rs:WP_032214913	DNA topoisomerase III, partial [Escherichia coli].	28.33	639	414	16	1	610	1	624	3e-74	263
rs:WP_034768980	DNA topoisomerase III [Bacillus thermoamylovorans].	28.59	717	468	18	1	681	1	709	3e-74	265
rs:WP_014108299	DNA topoisomerase III [Glaciecola nitratireducens].	31.00	613	384	14	1	581	1	606	3e-74	263
rs:WP_039498870	DNA topoisomerase III [Pectobacterium carotovorum].	28.71	641	414	15	1	614	1	625	3e-74	264
rs:WP_002344553	DNA topoisomerase III, partial [Enterococcus faecium].	30.98	581	356	13	41	611	3	548	3e-74	263
tr:D4K2M3_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.63	621	388	18	30	627	13	607	3e-74	263
rs:WP_033626788	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	3e-74	265
rs:WP_027952609	DNA topoisomerase I [Hallella seregens].	30.35	715	423	22	4	673	5	689	3e-74	265
rs:WP_034264488	DNA topoisomerase III [Bacillus sp. Aph1].	29.49	729	437	22	1	675	1	706	3e-74	265
rs:WP_042971805	DNA topoisomerase I [Bacteroides fragilis].	27.97	708	461	19	1	684	1	683	3e-74	265
rs:WP_042210448	DNA topoisomerase III [Paenibacillus borealis].	30.30	637	387	17	3	615	4	607	3e-74	265
rs:WP_010752776	DNA topoisomerase III [Enterococcus asini].	29.27	656	408	17	2	644	4	616	3e-74	264
rs:WP_023053285	DNA topoisomerase III [Megasphaera sp. BV3C16-1].	28.77	643	415	12	1	616	1	627	3e-74	265
rs:WP_002164824	DNA topoisomerase III [Bacillus cereus].	30.14	700	448	18	2	679	4	684	3e-74	264
rs:WP_017511104	MULTISPECIES: DNA topoisomerase III [Cupriavidus].	29.01	717	445	21	3	677	5	699	3e-74	268
rs:WP_033947838	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	29.04	675	423	20	1	638	1	656	3e-74	264
rs:WP_008642749	DNA topoisomerase III [Cupriavidus sp. HMR-1].	29.01	717	445	21	3	677	5	699	3e-74	268
rs:WP_033591694	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	3e-74	264
rs:WP_005597148	DNA topoisomerase III [Actinobacillus pleuropneumoniae].	30.93	637	399	17	1	606	1	627	3e-74	263
rs:WP_021289198	DNA topoisomerase III [Virgibacillus sp. CM-4].	31.11	630	402	17	3	615	5	619	3e-74	265
rs:WP_025920348	DNA topoisomerase III [Pectobacterium wasabiae].	28.83	659	424	17	1	629	1	644	3e-74	264
rs:WP_028115166	DNA topoisomerase III [Ferrimonas senticii].	29.02	610	390	14	3	581	4	601	3e-74	263
rs:WP_014298777	DNA topoisomerase I [Bacteroides fragilis].	28.59	696	451	20	1	673	1	673	3e-74	265
rs:WP_026677034	DNA topoisomerase III [Fictibacillus gelatini].	28.53	729	469	19	1	686	1	720	3e-74	265
rs:WP_035881171	DNA topoisomerase III [Cupriavidus metallidurans].	29.01	717	445	21	3	677	5	699	3e-74	268
rs:WP_024635340	DNA topoisomerase III, partial [Enterococcus faecium].	31.15	581	355	13	41	611	3	548	3e-74	263
rs:WP_009090442	DNA topoisomerase [Elizabethkingia anophelis].	30.26	704	437	21	1	680	1	674	3e-74	264
rs:WP_005809261	DNA topoisomerase I [Bacteroides fragilis].	30.08	708	444	21	1	684	1	681	3e-74	264
rs:WP_029306833	DNA topoisomerase III [Cupriavidus metallidurans].	29.01	717	445	21	3	677	5	699	3e-74	268
rs:WP_011517984	DNA topoisomerase III [Cupriavidus metallidurans].	29.01	717	445	21	3	677	5	699	3e-74	268
tr:D2YDR8_VIBMI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.81	620	374	16	2	581	9	613	3e-74	263
rs:WP_010784036	DNA topoisomerase III [Enterococcus faecalis].	29.67	664	395	19	2	644	5	617	3e-74	264
rs:WP_015870990	DNA topoisomerase III [Edwardsiella ictaluri].	29.52	620	380	18	1	581	1	602	3e-74	263
rs:WP_009433650	DNA topoisomerase I [Porphyromonas sp. oral taxon 279].	30.14	700	426	22	4	673	5	671	3e-74	264
rs:WP_002356968	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	3e-74	264
rs:WP_033660098	DNA topoisomerase III [Enterococcus faecalis].	29.97	664	393	19	2	644	5	617	4e-74	264
rs:WP_032843242	DNA topoisomerase I [Bacteroides ovatus].	28.97	711	450	22	1	684	1	683	4e-74	264
rs:WP_046674940	DNA topoisomerase I [Sphingobacterium sp. Ag1].	30.34	712	444	20	1	676	1	696	4e-74	265
rs:WP_032734795	DNA topoisomerase III, partial [Bifidobacterium breve].	27.27	748	452	23	1	679	1	725	4e-74	265
rs:WP_021640469	DNA topoisomerase [[Clostridium] symbiosum].	30.24	658	408	19	3	627	4	643	4e-74	265
rs:WP_029714564	DNA topoisomerase III [Bacillus sp. JGI 001006-L10].	29.63	729	436	22	1	675	1	706	4e-74	265
rs:WP_015238851	DNA topoisomerase III [Candidatus Kinetoplastibacterium crithidii].	31.23	746	400	27	2	680	4	703	4e-74	266
rs:WP_020334544	DNA topoisomerase III [Vibrio natriegens].	30.07	612	389	13	2	581	3	607	4e-74	263
rs:WP_033598758	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	4e-74	264
rs:WP_033578745	DNA topoisomerase III [Bacillus aryabhattai].	29.49	729	437	22	1	675	1	706	4e-74	265
rs:WP_040031775	DNA topoisomerase III [Pectobacterium carotovorum].	28.59	640	416	14	1	614	1	625	4e-74	263
rs:WP_001536202	DNA topoisomerase III family protein [Escherichia coli].	27.63	637	421	14	1	610	1	624	4e-74	263
rs:WP_028408630	DNA topoisomerase III [Bacillus sp. 171095_106].	29.70	660	405	17	3	646	4	620	4e-74	264
rs:WP_025752281	DNA topoisomerase III [Bacillus flexus].	29.70	660	405	17	3	646	4	620	4e-74	264
rs:WP_042172682	DNA topoisomerase III [Paenibacillus sp. FSL R7-0331].	29.20	637	394	16	3	615	4	607	4e-74	265
rs:WP_039106785	DNA topoisomerase III, partial [Frischella perrara].	30.95	630	360	19	2	581	8	612	4e-74	262
tr:A0A073IAB4_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KEJ86500.1};	28.37	698	450	20	1	673	1	673	4e-74	264
rs:WP_033929799	DNA topoisomerase III [Vibrio cholerae].	30.52	616	381	14	2	581	3	607	4e-74	263
rs:WP_016612333	DNA topoisomerase [Enterococcus faecium].	30.04	719	458	18	3	686	4	712	4e-74	265
rs:WP_032492626	DNA topoisomerase III [Pseudomonas putida].	29.09	691	419	19	1	646	1	665	4e-74	263
rs:WP_022400369	DNA topoisomerase [Roseburia sp. CAG:471].	30.75	657	400	20	3	626	4	638	4e-74	265
tr:E4IH74_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.06	632	387	16	28	644	6	597	4e-74	263
rs:WP_045290378	DNA topoisomerase III [Bacillus aryabhattai].	29.79	658	407	17	3	646	4	620	4e-74	264
rs:WP_041021229	DNA topoisomerase III [Pseudomonas sp. SHC52].	27.61	670	436	16	1	638	1	653	4e-74	263
rs:WP_043701074	DNA topoisomerase III, partial [Tepidimonas taiwanensis].	30.21	682	380	23	3	611	8	666	4e-74	267
rs:WP_028548262	DNA topoisomerase III [Paenibacillus sp. UNC451MF].	29.05	692	420	19	3	657	4	661	4e-74	265
rs:WP_004538149	DNA topoisomerase III [Burkholderia pseudomallei].	28.48	618	401	14	1	587	1	608	4e-74	263
rs:WP_025477199	DNA topoisomerase III, partial [Enterococcus faecium].	30.98	581	356	13	41	611	3	548	5e-74	263
rs:WP_032482725	DNA topoisomerase III [Vibrio cholerae].	30.81	620	374	16	2	581	3	607	5e-74	263
rs:WP_004353783	DNA topoisomerase I [Prevotella denticola].	30.71	700	429	23	1	673	2	672	5e-74	264
tr:H1BTD4_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.53	638	414	17	1	610	1	624	5e-74	263
tr:A0A0A4GCQ0_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.33	639	417	16	1	614	1	623	5e-74	263
rs:WP_007721869	MULTISPECIES: DNA topoisomerase III [Carnobacterium].	29.34	709	462	16	2	680	3	702	5e-74	264
rs:WP_039310314	DNA topoisomerase III [Paenibacillus sp. IHB B 3415].	30.30	637	387	18	3	615	4	607	5e-74	264
rs:WP_036661964	DNA topoisomerase III [Paenibacillus sp. FSL H8-457].	29.29	635	397	15	3	615	4	608	5e-74	264
rs:WP_012639367	DNA topoisomerase III [Thioalkalivibrio sulfidiphilus].	28.53	666	418	17	1	629	1	645	5e-74	263
rs:WP_023101001	hypothetical protein [Pseudomonas aeruginosa].	27.77	695	426	19	1	646	1	668	5e-74	263
rs:WP_040427933	DNA topoisomerase III, partial [Acetivibrio cellulolyticus].	31.03	593	383	12	3	581	5	585	5e-74	261
tr:A0A073BI74_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.43	621	377	16	41	646	3	583	5e-74	263
rs:WP_005237632	DNA topoisomerase [Enterococcus casseliflavus].	29.79	715	465	18	3	686	4	712	5e-74	265
rs:WP_028227275	DNA topoisomerase III [Burkholderia ferrariae].	30.15	723	433	22	3	680	5	700	5e-74	267
rs:WP_036562672	DNA topoisomerase III, partial [Candidatus Schmidhempelia bombi].	31.01	632	363	19	1	581	1	610	5e-74	262
rs:WP_039170259	conjugal transfer protein TraE [Gallibacterium anatis].	28.66	764	446	26	1	684	1	745	5e-74	265
rs:WP_025478548	DNA topoisomerase III, partial [Enterococcus faecium].	30.93	582	355	14	41	611	3	548	5e-74	263
tr:E6QCV3_9ZZZZ	SubName: Full=Putative DNA topoisomerase III (TopB) {ECO:0000313|EMBL:CBI05029.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI05029.1};	28.72	686	423	18	1	631	1	675	5e-74	263
rs:WP_008937881	DNA topoisomerase III [Marinobacter santoriniensis].	29.12	649	416	15	1	615	1	639	5e-74	264
rs:WP_013083050	DNA topoisomerase III [Bacillus megaterium].	29.89	659	405	19	3	646	4	620	5e-74	264
rs:WP_010731992	DNA topoisomerase III [Enterococcus faecium].	30.98	581	356	13	41	611	3	548	6e-74	263
rs:WP_045785422	DNA topoisomerase III [Ralstonia mannitolilytica].	29.87	713	433	23	3	673	5	692	6e-74	267
rs:WP_019036208	MULTISPECIES: DNA topoisomerase I [Prevotella].	30.41	707	422	20	1	673	2	672	6e-74	264
rs:WP_033656182	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	6e-74	263
rs:WP_009099470	DNA topoisomerase III [Halomonas sp. GFAJ-1].	29.43	581	378	11	1	560	1	570	6e-74	262
rs:WP_020750047	DNA topoisomerase III [Ralstonia solanacearum].	29.69	714	437	22	3	673	5	696	6e-74	267
rs:WP_004338303	MULTISPECIES: DNA topoisomerase I [Prevotella].	30.27	707	423	20	1	673	2	672	6e-74	263
rs:WP_036651035	DNA topoisomerase I [Parabacteroides distasonis].	28.86	700	444	23	1	673	1	673	6e-74	264
rs:WP_035649896	DNA topoisomerase I [Flavobacterium sp. Fl].	30.86	700	431	21	1	673	1	674	6e-74	263
rs:WP_010777799	DNA topoisomerase III [Enterococcus faecalis].	30.30	627	373	16	2	611	5	584	6e-74	263
tr:S4EN54_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.97	664	393	19	2	644	61	673	6e-74	265
rs:WP_033500273	hypothetical protein [Bifidobacterium stercoris].	27.60	732	461	19	1	677	1	718	6e-74	264
rs:WP_024608541	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	29.64	614	391	14	1	581	1	606	6e-74	264
rs:WP_017170471	DNA topoisomerase [Xanthomonas axonopodis].	29.96	691	417	21	1	640	1	675	6e-74	263
rs:WP_005897679	DNA topoisomerase III [Aeromonas molluscorum].	29.71	616	383	16	1	581	1	601	6e-74	263
rs:WP_024718102	DNA topoisomerase III [Pseudomonas putida].	28.43	686	431	19	1	646	1	666	6e-74	263
rs:WP_002374513	DNA topoisomerase III [Enterococcus faecalis].	29.97	664	393	19	2	644	5	617	6e-74	263
rs:WP_014232576	DNA topoisomerase III [Vibrio sp. EJY3].	29.47	621	381	13	2	581	3	607	6e-74	263
rs:WP_021196961	DNA topoisomerase III [Ralstonia sp. AU12-08].	29.97	714	431	22	3	673	5	692	6e-74	267
rs:WP_034165111	DNA topoisomerase III [Edwardsiella tarda].	29.32	614	389	16	1	581	1	602	7e-74	262
rs:WP_007160882	DNA topoisomerase III [Pseudomonas psychrotolerans].	27.86	646	416	14	1	614	1	628	7e-74	263
rs:WP_044736728	DNA topoisomerase III [Geobacillus kaustophilus].	30.89	709	451	19	1	679	1	700	7e-74	264
tr:U2X8N2_GEOKU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.61	662	405	20	4	646	1	620	7e-74	263
rs:WP_039086231	conjugal transfer protein TraE [Gallibacterium anatis].	28.80	764	445	26	1	684	1	745	7e-74	265
tr:J6YLM5_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.06	632	387	16	28	644	6	597	7e-74	263
rs:WP_010818429	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	7e-74	263
rs:WP_001428196	DNA topoisomerase III family protein [Escherichia coli].	28.37	638	415	17	1	610	1	624	7e-74	263
rs:WP_031413506	DNA topoisomerase III [Brevibacillus laterosporus].	28.79	719	460	18	1	676	1	710	7e-74	265
rs:WP_036227450	DNA topoisomerase III [Lysinibacillus sphaericus].	29.06	733	455	21	1	682	1	719	7e-74	264
rs:WP_032842963	DNA topoisomerase I [Bacteroides ovatus].	28.51	712	452	21	1	684	1	683	7e-74	263
rs:WP_043988817	DNA topoisomerase III [Pectobacterium wasabiae].	28.86	641	413	15	1	614	1	625	7e-74	263
rs:WP_033931233	DNA topoisomerase III [Vibrio cholerae].	30.48	620	376	15	2	581	3	607	7e-74	262
rs:WP_036805062	DNA topoisomerase III [Planomicrobium glaciei].	28.55	711	461	18	3	681	4	699	7e-74	263
rs:WP_039974109	DNA topoisomerase III [Vibrio jasicida].	30.39	612	387	14	2	581	3	607	7e-74	262
rs:WP_033656229	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	8e-74	263
rs:WP_033143219	DNA topoisomerase III [Blautia producta].	29.42	690	446	16	1	669	1	670	8e-74	263
tr:S2ZM87_BIFBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EPD75485.1};	27.27	748	452	23	1	679	1	725	8e-74	265
rs:WP_000197426	DNA topoisomerase III [Vibrio cholerae].	30.48	620	376	15	2	581	3	607	8e-74	262
rs:WP_032475343	DNA topoisomerase III [Vibrio cholerae].	30.81	620	374	16	2	581	3	607	8e-74	262
rs:WP_002362072	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	8e-74	263
tr:K5V6Y2_9VIBR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.23	612	388	14	2	581	3	607	8e-74	262
rs:WP_004343312	MULTISPECIES: DNA topoisomerase I [Prevotellaceae].	30.16	703	432	20	4	673	5	681	8e-74	263
rs:WP_011616268	DNA topoisomerase III [Cupriavidus necator].	29.43	717	441	22	3	677	5	698	8e-74	267
rs:WP_004346383	DNA topoisomerase I [Prevotella buccae].	30.74	706	423	22	1	673	1	673	8e-74	263
rs:WP_010822981	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	8e-74	263
rs:WP_047012732	DNA topoisomerase III [Spongiibacter sp. IMCC21906].	28.28	679	427	17	1	640	1	658	8e-74	263
rs:WP_000197441	DNA topoisomerase III [Vibrio cholerae].	30.48	620	376	15	2	581	3	607	8e-74	262
rs:WP_031423960	DNA topoisomerase III [Xanthomonas axonopodis].	28.68	680	425	18	1	641	1	659	8e-74	263
rs:WP_032530912	DNA topoisomerase I [Bacteroides fragilis].	28.71	700	445	21	1	673	1	673	8e-74	263
tr:A0A0A7S2M8_9GAMM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.95	630	360	19	2	581	8	612	8e-74	261
rs:WP_034743444	DNA topoisomerase III [Bacillus wakoensis].	29.78	722	454	20	1	681	1	710	8e-74	264
rs:WP_009093060	DNA topoisomerase [Elizabethkingia anophelis].	30.26	704	437	21	1	680	1	674	8e-74	263
tr:D4ELR4_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.82	664	394	19	2	644	61	673	8e-74	264
sp:TOP3_VIBCH	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	30.48	620	376	15	2	581	3	607	9e-74	262
rs:WP_032585411	DNA topoisomerase I [Bacteroides fragilis].	28.59	696	451	20	1	673	1	673	9e-74	263
rs:WP_039869614	DNA topoisomerase III [Paenibacillus sp. FSL R7-0273].	29.67	637	391	17	3	615	4	607	9e-74	263
tr:S4FHU0_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.97	664	393	19	2	644	61	673	9e-74	264
rs:WP_017166887	DNA topoisomerase [Xanthomonas axonopodis].	30.21	682	408	21	1	630	1	666	9e-74	263
rs:WP_041845987	DNA topoisomerase III [Bacillus thermoamylovorans].	28.45	717	469	18	1	681	1	709	9e-74	263
rs:WP_026591986	DNA topoisomerase III [Bacillus sp. UNC437CL72CviS29].	30.47	709	426	21	1	661	1	690	9e-74	263
rs:WP_000197440	DNA topoisomerase III [Vibrio cholerae].	30.48	620	376	15	2	581	3	607	9e-74	262
rs:WP_006356165	DNA topoisomerase III [[Clostridium] methylpentosum].	30.12	644	411	20	3	627	5	628	9e-74	264
rs:WP_019427399	DNA topoisomerase III [Limnohabitans sp. Rim28].	29.22	722	436	24	3	666	4	708	9e-74	268
rs:WP_041413492	DNA topoisomerase III, partial [Shewanella frigidimarina].	29.70	643	390	14	1	594	1	630	9e-74	262
rs:WP_022940269	DNA topoisomerase III [Psychromonas hadalis].	31.97	610	369	16	1	578	1	596	9e-74	262
tr:E6GNJ7_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.82	664	394	19	2	644	61	673	9e-74	264
tr:Q084R2_SHEFN	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.70	643	390	14	1	594	1	630	1e-73	262
rs:WP_016973531	DNA topoisomerase III [Pseudomonas tolaasii].	27.55	657	433	15	1	629	1	642	1e-73	262
rs:WP_036586587	DNA topoisomerase III [Ochrobactrum anthropi].	28.29	654	398	16	1	611	1	626	1e-73	263
tr:F2MQ93_ENTFO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.82	664	394	19	2	644	61	673	1e-73	264
rs:WP_010828882	DNA topoisomerase III [Enterococcus faecalis].	29.70	660	400	18	2	644	5	617	1e-73	263
rs:WP_003487097	DNA topoisomerase III [Xanthomonas citri].	27.58	660	434	17	1	630	1	646	1e-73	263
rs:WP_010708822	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	1e-73	263
tr:A0A0C5J2H9_9RHOO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AJP49262.1};	28.95	715	442	24	2	673	4	695	1e-73	266
rs:WP_010496819	DNA topoisomerase III [Lactobacillus acidipiscis].	30.10	618	386	13	2	611	3	582	1e-73	263
rs:WP_010710575	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	1e-73	263
tr:R4BFE2_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.37	619	376	16	41	644	3	581	1e-73	262
rs:WP_010283960	DNA topoisomerase III [Bacillus timonensis].	29.52	725	455	18	1	681	1	713	1e-73	263
rs:WP_010815836	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	1e-73	263
rs:WP_018977667	hypothetical protein [Saccharibacillus kuerlensis].	28.30	749	458	22	1	681	1	738	1e-73	264
rs:WP_010746590	DNA topoisomerase III [Enterococcus raffinosus].	30.05	619	384	13	2	611	3	581	1e-73	263
rs:WP_002388224	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	1e-73	263
tr:R2AXZ8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.21	619	377	16	41	644	3	581	1e-73	262
rs:WP_022583212	DNA topoisomerase III family protein [Peptoclostridium difficile].	28.22	698	446	19	2	670	5	676	1e-73	263
rs:WP_005667784	DNA topoisomerase III [Haemophilus influenzae].	29.46	662	415	18	1	629	1	643	1e-73	263
rs:WP_008733910	DNA topoisomerase III [Alcanivorax pacificus].	28.38	666	419	17	1	629	1	645	1e-73	262
rs:WP_010811329	DNA topoisomerase III [Ralstonia sp. GA3-3].	29.29	717	442	22	3	677	5	698	1e-73	266
rs:WP_033542386	DNA topoisomerase III [Planococcus sp. CAU13].	28.71	721	447	20	3	681	4	699	1e-73	263
rs:WP_036146170	DNA topoisomerase III [Lysinibacillus fusiformis].	29.02	734	455	21	1	682	1	720	1e-73	263
rs:WP_025907666	DNA topoisomerase III [Bacillus flexus].	30.43	608	373	14	1	573	1	593	1e-73	263
rs:WP_042124020	DNA topoisomerase III [Paenibacillus sp. FSL R5-0345].	29.40	636	393	16	3	615	4	606	1e-73	263
rs:WP_000197430	DNA topoisomerase III [Vibrio albensis].	30.65	620	375	16	2	581	3	607	1e-73	261
rs:WP_014460501	DNA topoisomerase III [Bacillus megaterium].	29.21	736	430	22	1	675	1	706	1e-73	263
rs:WP_002329557	DNA topoisomerase III, partial [Enterococcus faecium].	30.81	581	357	13	41	611	3	548	1e-73	262
rs:WP_000197438	DNA topoisomerase III [Vibrio cholerae].	30.48	620	376	15	2	581	3	607	1e-73	261
rs:WP_015601729	DNA topoisomerase III family protein [Burkholderia thailandensis].	29.13	618	397	15	1	587	1	608	1e-73	262
rs:WP_000197436	DNA topoisomerase III [Vibrio cholerae].	30.65	620	375	15	2	581	3	607	1e-73	261
rs:WP_033627478	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	1e-73	263
rs:WP_039836674	DNA topoisomerase III [Vibrio rumoiensis].	29.92	615	391	13	1	581	5	613	1e-73	262
rs:WP_009224508	DNA topoisomerase III [Paenibacillus sp. oral taxon 786].	29.58	666	413	18	3	646	4	635	1e-73	263
rs:WP_025150038	DNA topoisomerase III [Bacillus sp. H1a].	29.94	708	431	18	1	661	1	690	1e-73	263
rs:WP_033600878	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	1e-73	263
rs:WP_010773489	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	1e-73	263
rs:WP_037499141	DNA topoisomerase I [Sphingobacterium sp. ACCC 05744].	30.51	708	442	20	1	673	1	693	1e-73	263
rs:WP_017690704	DNA topoisomerase III [Paenibacillus sp. PAMC 26794].	28.70	683	423	20	3	659	4	648	1e-73	263
rs:WP_001720566	DNA topoisomerase III family protein [Escherichia coli].	28.53	638	414	17	1	610	1	624	1e-73	262
rs:WP_013082807	DNA topoisomerase III [Bacillus megaterium].	29.63	729	436	22	1	675	1	706	1e-73	263
rs:WP_011045511	DNA topoisomerase III [Colwellia psychrerythraea].	31.12	633	373	20	1	583	1	620	1e-73	261
rs:WP_039198697	DNA topoisomerase III [Bifidobacterium kashiwanohense].	27.88	739	458	20	1	679	1	724	1e-73	263
rs:WP_035286737	DNA topoisomerase III, partial [Brevibacillus massiliensis].	30.14	627	401	14	1	602	1	615	1e-73	261
rs:WP_006789974	DNA topoisomerase [Anaeroglobus geminatus].	30.08	645	404	15	1	615	1	628	1e-73	263
rs:WP_038642446	DNA topoisomerase III [Pseudoalteromonas sp. OCN003].	31.80	607	368	16	1	574	1	594	1e-73	261
rs:WP_025070215	DNA topoisomerase I [Prevotella oulorum].	31.00	700	420	23	4	673	5	671	1e-73	263
rs:WP_000197439	DNA topoisomerase III [Vibrio cholerae].	30.48	620	376	15	2	581	3	607	1e-73	261
rs:WP_003038090	DNA topoisomerase [Streptococcus anginosus].	33.55	602	349	15	3	588	4	570	1e-73	259
rs:WP_010817457	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	1e-73	263
rs:WP_002414495	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	1e-73	263
tr:Q2B0Q7_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.05	579	381	12	1	557	3	579	2e-73	259
rs:WP_021620860	DNA topoisomerase [Aneurinibacillus aneurinilyticus].	28.49	674	412	21	3	646	4	637	2e-73	263
rs:WP_036125316	MULTISPECIES: DNA topoisomerase III [Lysinibacillus].	29.02	734	455	21	1	682	1	720	2e-73	263
rs:WP_008566167	DNA topoisomerase I [Prevotella maculosa].	30.21	715	412	22	4	673	5	677	2e-73	263
rs:WP_009673239	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	29.81	681	399	21	3	646	5	643	2e-73	263
rs:WP_002380452	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	2e-73	262
rs:WP_017759289	DNA topoisomerase III [Pseudacidovorax intermedius].	29.62	736	425	25	3	666	5	719	2e-73	267
rs:WP_038694802	DNA topoisomerase I [Sphingobacterium sp. ML3W].	31.70	713	423	25	1	680	1	682	2e-73	262
rs:WP_026640596	DNA topoisomerase III [Bordetella petrii].	29.02	727	428	24	3	675	5	697	2e-73	266
rs:WP_026557999	DNA topoisomerase III [Bacillus sp. NSP2.1].	31.16	661	394	20	3	627	5	640	2e-73	263
rs:WP_025752003	DNA topoisomerase III [Bacillus flexus].	29.49	729	437	22	1	675	1	706	2e-73	263
rs:WP_001575003	MULTISPECIES: DNA topoisomerase III [Staphylococcus].	30.49	728	440	20	1	687	1	703	2e-73	263
tr:L8A5I9_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.37	619	376	16	41	644	3	581	2e-73	261
rs:WP_040073611	DNA topoisomerase III [Vibrio cholerae].	30.48	620	376	15	2	581	3	607	2e-73	261
rs:WP_042739088	DNA topoisomerase III [Staphylococcus gallinarum].	33.12	640	367	22	3	615	4	609	2e-73	263
rs:WP_016278636	DNA topoisomerase III [Bacteroides massiliensis].	28.07	709	461	21	1	684	1	685	2e-73	263
rs:WP_026726938	DNA topoisomerase I [Flavobacterium denitrificans].	30.23	698	444	20	1	676	1	677	2e-73	262
rs:WP_024767679	DNA topoisomerase III [Pseudomonas nitroreducens].	28.92	664	418	20	1	629	1	645	2e-73	262
rs:WP_016181416	DNA topoisomerase III [Enterococcus avium].	28.82	687	424	18	2	671	3	641	2e-73	262
rs:WP_005800238	DNA topoisomerase I [Bacteroides fragilis].	28.59	696	451	20	1	673	1	673	2e-73	262
rs:WP_031892018	DNA topoisomerase III, partial [Staphylococcus aureus].	32.98	570	349	15	3	557	4	555	2e-73	259
rs:WP_031552787	DNA topoisomerase III [Gemella sanguinis].	31.97	585	367	14	3	577	4	567	2e-73	263
rs:WP_017530155	DNA topoisomerase III [Pseudomonas fluorescens].	27.86	664	432	15	1	633	1	648	2e-73	261
rs:WP_021846108	DNA topoisomerase [Blautia hydrogenotrophica CAG:147].	29.25	653	415	17	3	627	4	637	2e-73	263
rs:WP_003413130	DNA topoisomerase III [Pseudomonas syringae].	28.72	686	428	19	1	646	1	665	2e-73	262
rs:WP_010820938	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	2e-73	262
rs:WP_032470230	DNA topoisomerase III [Vibrio cholerae].	30.06	622	370	19	1	574	1	605	2e-73	261
rs:WP_010561672	DNA topoisomerase III [Pseudoalteromonas spongiae].	31.18	619	380	17	1	584	1	608	2e-73	261
rs:WP_036161385	DNA topoisomerase III [Lysinibacillus sphaericus].	29.02	727	463	19	1	682	1	719	2e-73	263
rs:WP_002330030	DNA topoisomerase III, partial [Enterococcus faecium].	30.37	619	376	16	41	644	3	581	2e-73	261
rs:WP_009372245	DNA topoisomerase III [Veillonella sp. oral taxon 780].	30.08	615	392	10	1	581	1	611	2e-73	264
rs:WP_015389216	DNA topoisomerase III [Candidatus Kinetoplastibacterium galatii].	31.11	736	413	28	2	680	4	702	2e-73	265
rs:WP_025729379	DNA topoisomerase III [Bacillus ginsengihumi].	29.78	712	446	22	3	673	5	703	2e-73	263
rs:WP_032473562	DNA topoisomerase III [Vibrio cholerae].	30.65	620	375	16	2	581	3	607	2e-73	261
rs:WP_042927335	DNA topoisomerase III [Pseudomonas chloritidismutans].	29.35	620	389	14	1	586	1	605	2e-73	261
rs:WP_011199909	DNA topoisomerase III [[Mannheimia] succiniciproducens].	31.08	621	371	20	1	581	1	604	2e-73	261
rs:WP_027678685	DNA topoisomerase III [Ralstonia sp. UNC404CL21Col].	29.92	712	434	22	3	673	5	692	2e-73	265
rs:WP_006094529	MULTISPECIES: DNA topoisomerase III [Bacillus].	32.05	599	370	14	1	573	1	588	2e-73	263
rs:WP_032854695	DNA topoisomerase I [Bacteroides ovatus].	28.51	712	452	21	1	684	1	683	2e-73	262
rs:WP_010825356	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	2e-73	262
rs:WP_038206454	DNA topoisomerase III [Xenophilus azovorans].	29.43	734	429	24	3	666	5	719	2e-73	267
rs:WP_042795811	DNA topoisomerase III [Achromobacter xylosoxidans].	29.97	724	425	25	3	675	5	697	2e-73	265
rs:WP_000766776	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.10	701	426	17	1	655	1	683	2e-73	263
rs:WP_025115653	DNA topoisomerase III [Lysinibacillus fusiformis].	29.02	727	463	19	1	682	1	719	2e-73	263
rs:WP_008374266	DNA topoisomerase III [Pseudomonas sp. M47T1].	27.88	660	426	17	1	629	1	641	2e-73	261
tr:R2LGJ5_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.37	619	376	16	41	644	3	581	2e-73	261
rs:WP_035565616	DNA topoisomerase III [Halomonas sp. KO116].	28.71	613	398	12	1	584	1	603	2e-73	263
rs:WP_004584872	DNA topoisomerase [Porphyromonas gingivalis].	30.78	705	422	23	4	673	5	678	2e-73	262
tr:R2RSK6_ENTCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.79	715	465	18	3	686	10	718	2e-73	263
rs:WP_005687564	DNA topoisomerase III [Haemophilus influenzae].	29.35	661	417	17	1	629	1	643	2e-73	262
rs:WP_033592006	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	2e-73	262
rs:WP_029463186	DNA topoisomerase III, partial [Comamonadaceae bacterium H1].	32.14	669	378	25	3	611	8	660	2e-73	266
tr:E0H3Y9_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.82	664	394	19	2	644	61	673	2e-73	263
tr:A0A087DS06_9BIFI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KFI98306.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KFI98306.1};	27.46	732	462	19	1	677	13	730	2e-73	263
tr:A0A059MY33_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.82	664	394	19	2	644	61	673	2e-73	263
rs:WP_011107114	DNA topoisomerase I [Bacteroides thetaiotaomicron].	28.31	710	456	18	1	684	1	683	2e-73	262
rs:WP_040041719	DNA topoisomerase III [Herbaspirillum sp. TSA66].	29.82	731	442	23	3	687	5	710	2e-73	265
tr:J6WLB4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.91	632	388	16	28	644	6	597	2e-73	261
tr:E6HHC9_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.82	664	394	19	2	644	61	673	2e-73	263
rs:WP_000766760	DNA topoisomerase III [Bacillus cereus].	29.53	701	443	18	1	661	1	690	2e-73	262
tr:R2NIZ1_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.37	619	376	16	41	644	3	581	2e-73	261
rs:WP_038172978	DNA topoisomerase III [Vibrio pacinii].	30.29	614	385	14	2	581	3	607	2e-73	261
rs:WP_032538771	DNA topoisomerase, partial [Peptoclostridium difficile].	33.22	569	342	14	31	587	3	545	2e-73	258
rs:WP_012052641	MULTISPECIES: DNA topoisomerase III [Pseudomonas putida group].	27.80	669	437	16	1	640	1	652	2e-73	261
rs:WP_044127250	DNA topoisomerase III [Vibrio cholerae].	30.32	620	377	15	2	581	3	607	2e-73	261
tr:W4SCH7_9XANT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.36	670	416	17	1	629	1	647	2e-73	261
rs:WP_012819086	DNA topoisomerase III [Paenibacillus sp. Y412MC10].	28.98	635	399	15	3	615	4	608	2e-73	262
rs:WP_000766761	DNA topoisomerase III [Bacillus cereus].	29.53	701	443	18	1	661	1	690	2e-73	262
rs:WP_007783982	DNA topoisomerase III [Brevibacillus sp. CF112].	31.16	661	394	20	3	627	5	640	2e-73	263
rs:WP_036863984	MULTISPECIES: DNA topoisomerase I [Prevotella].	30.27	707	423	22	1	673	2	672	2e-73	262
rs:WP_043775642	DNA topoisomerase III, partial [Desulfomicrobium escambiense].	30.46	591	356	16	3	561	5	572	2e-73	259
rs:WP_039832234	DNA topoisomerase III [Paenibacillus sonchi].	29.55	643	384	17	3	615	4	607	2e-73	262
rs:WP_012768236	MULTISPECIES: DNA topoisomerase III [Dickeya].	28.18	685	431	21	1	646	1	663	2e-73	261
tr:A0A091CID4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.37	619	376	16	41	644	3	581	2e-73	261
rs:WP_042266102	DNA topoisomerase III [Burkholderia heleia].	30.11	714	429	22	3	673	5	691	3e-73	265
rs:WP_010027006	DNA topoisomerase III [Sporolactobacillus inulinus].	28.96	663	412	20	3	646	5	627	3e-73	262
rs:WP_036166280	DNA topoisomerase III [Lysinibacillus sphaericus].	29.02	727	463	19	1	682	1	719	3e-73	263
rs:WP_012564926	DNA topoisomerase III [Haemophilus influenzae].	29.35	661	417	17	1	629	1	643	3e-73	261
rs:WP_028406384	DNA topoisomerase III [Bacillus sp. J13].	29.72	636	393	16	3	615	4	608	3e-73	262
rs:WP_043300054	DNA topoisomerase III [Burkholderia sp. TSV202].	28.53	617	401	15	1	587	1	607	3e-73	261
rs:WP_018418959	DNA topoisomerase III [Burkholderia sp. WSM4176].	30.64	718	420	25	3	673	5	691	3e-73	265
rs:WP_040975693	DNA topoisomerase III [Pasteurella sp. FF6].	29.35	661	417	17	1	629	1	643	3e-73	261
rs:WP_002360012	DNA topoisomerase III [Enterococcus faecalis].	30.30	627	373	16	2	611	5	584	3e-73	262
rs:WP_026675398	DNA topoisomerase III [Bacillus bogoriensis].	29.66	735	434	19	1	681	1	706	3e-73	262
rs:WP_035523344	DNA topoisomerase III [Burkholderia sacchari].	29.97	714	430	21	3	673	5	691	3e-73	265
rs:WP_023122311	hypothetical protein [Pseudomonas aeruginosa].	29.07	664	417	18	1	629	1	645	3e-73	261
rs:WP_012294074	DNA topoisomerase III [Lysinibacillus sphaericus].	29.02	727	463	19	1	682	1	719	3e-73	263
rs:WP_014991412	DNA topoisomerase III [Actinobacillus suis].	30.88	638	398	18	1	606	1	627	3e-73	261
rs:WP_026903538	DNA topoisomerase III [Pedobacter glucosidilyticus].	29.98	617	384	17	1	589	1	597	3e-73	260
rs:WP_025876744	DNA topoisomerase I [Prevotella corporis].	29.22	705	436	21	4	673	5	681	3e-73	262
rs:WP_008175979	DNA topoisomerase III [Bacillus sp. B14905].	29.02	727	463	19	1	682	1	719	3e-73	263
rs:WP_043711949	topoisomerase I [Weissella cibaria].	29.39	735	434	28	3	673	4	717	3e-73	263
rs:WP_010739950	DNA topoisomerase III [Enterococcus malodoratus].	28.68	687	425	18	2	671	3	641	3e-73	262
rs:WP_004361566	DNA topoisomerase III [Thauera phenylacetica].	29.73	730	437	24	2	682	4	706	3e-73	265
rs:WP_032476424	DNA topoisomerase III [Vibrio cholerae].	30.65	620	375	15	2	581	3	607	3e-73	261
rs:WP_047193235	DNA topoisomerase III [[Polyangium] brachysporum].	30.42	743	412	30	3	673	5	714	3e-73	265
rs:WP_023510288	DNA topoisomerase III [Sporolactobacillus laevolacticus].	29.91	662	407	18	3	646	5	627	3e-73	262
rs:WP_000766775	DNA topoisomerase III [Bacillus cereus].	30.08	708	430	18	1	661	1	690	3e-73	262
tr:E6ICX1_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.82	664	394	19	2	644	61	673	3e-73	263
rs:WP_034695777	DNA topoisomerase [Enterococcus casseliflavus].	29.79	715	465	18	3	686	4	712	3e-73	262
tr:T2NSF2_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.90	602	367	15	28	614	5	566	3e-73	261
rs:WP_006693725	DNA topoisomerase TopB [Selenomonas noxia].	27.64	673	426	17	1	630	1	655	3e-73	262
tr:D3LED0_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.21	619	377	16	41	644	3	581	3e-73	261
rs:WP_036680927	DNA topoisomerase III [Paenibacillus sp. FSL H8-237].	29.61	635	393	16	3	615	4	606	3e-73	262
rs:WP_005776763	DNA topoisomerase I [Bacteroides fragilis].	29.24	701	440	23	1	673	1	673	3e-73	262
rs:WP_006696787	hypothetical protein [Selenomonas noxia].	27.64	673	426	17	1	630	1	655	3e-73	262
rs:WP_010826160	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	3e-73	261
rs:WP_036559719	DNA topoisomerase III [Oligella urethralis].	29.96	731	429	26	3	681	5	704	3e-73	265
rs:WP_010823795	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	3e-73	261
rs:WP_019913667	DNA topoisomerase III [Paenibacillus sp. HW567].	29.04	637	395	16	3	615	4	607	3e-73	262
rs:WP_000197431	DNA topoisomerase III [Vibrio cholerae].	30.65	620	375	16	2	581	3	607	3e-73	261
rs:WP_013488617	DNA topoisomerase III [Bacillus cellulosilyticus].	29.61	716	453	19	1	673	1	708	3e-73	262
rs:WP_020798922	DNA topoisomerase III family protein [Pseudomonas sp. G5(2012)].	28.19	674	430	19	1	638	1	656	3e-73	261
rs:WP_003336735	DNA topoisomerase III [Brevibacillus laterosporus].	28.73	717	463	18	1	676	1	710	3e-73	263
rs:WP_028221532	DNA topoisomerase III [Burkholderia oxyphila].	29.97	714	430	21	3	673	5	691	3e-73	265
rs:WP_039127867	DNA topoisomerase III, partial [Gilliamella apicola].	30.91	618	380	19	2	581	8	616	3e-73	260
rs:WP_009347068	DNA topoisomerase I [Alloprevotella rava].	29.22	705	451	20	3	684	4	683	3e-73	261
tr:E6ILE0_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.82	664	394	19	2	644	61	673	3e-73	263
rs:WP_000197432	DNA topoisomerase III [Vibrio cholerae].	30.81	620	374	16	2	581	3	607	3e-73	260
rs:WP_021615661	DNA topoisomerase [Aggregatibacter sp. oral taxon 458].	30.68	616	369	16	1	572	1	602	3e-73	260
rs:WP_020913174	DNA topoisomerase III [Shewanella piezotolerans].	28.19	642	420	12	1	606	1	637	3e-73	261
rs:WP_040031623	DNA topoisomerase III [Pectobacterium carotovorum].	28.91	640	414	15	1	614	1	625	3e-73	261
rs:WP_022989658	DNA topoisomerase III [Marinobacter sp. ES-1].	28.90	647	418	12	1	615	1	637	4e-73	262
rs:WP_046213924	DNA topoisomerase III [Paenibacillus wulumuqiensis].	28.32	678	415	19	2	646	3	642	4e-73	262
rs:WP_024973868	DNA topoisomerase III [Ralstonia pickettii].	29.59	713	435	22	3	673	5	692	4e-73	265
tr:L2JGT7_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.21	619	377	16	41	644	3	581	4e-73	261
tr:E6FJ07_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.82	664	394	19	2	644	61	673	4e-73	263
rs:WP_045720885	DNA topoisomerase III, partial [Salmonella enterica].	32.60	549	335	16	61	581	16	557	4e-73	259
rs:WP_005944631	DNA topoisomerase III [Blautia hydrogenotrophica].	29.51	654	412	18	3	627	4	637	4e-73	262
rs:WP_034759339	DNA topoisomerase III [Bacillus vietnamensis].	28.81	729	454	20	1	681	1	712	4e-73	262
rs:WP_032533104	DNA topoisomerase I [Bacteroides fragilis].	28.90	706	457	19	1	684	1	683	4e-73	261
rs:WP_033932793	DNA topoisomerase III [Vibrio cholerae].	30.48	620	376	15	2	581	3	607	4e-73	260
rs:WP_014326561	DNA topoisomerase III [Haemophilus influenzae].	28.90	661	420	15	1	629	1	643	4e-73	261
rs:WP_042228689	DNA topoisomerase III [Paenibacillus chitinolyticus].	30.03	646	381	18	3	615	5	612	4e-73	262
rs:WP_031419831	DNA topoisomerase III [Lysinibacillus sphaericus].	28.89	727	464	19	1	682	1	719	4e-73	262
rs:WP_033625995	DNA topoisomerase III [Enterococcus faecalis].	29.52	664	396	19	2	644	5	617	4e-73	261
rs:WP_033624327	DNA topoisomerase III [Enterococcus faecalis].	29.82	664	394	19	2	644	5	617	4e-73	261
rs:WP_007749118	DNA topoisomerase I [Bacteroides finegoldii].	29.58	693	438	22	11	676	1	670	4e-73	261
rs:WP_045533713	DNA topoisomerase III, partial [Comamonadaceae bacterium A1].	31.99	669	379	25	3	611	8	660	4e-73	265
rs:WP_010830988	DNA topoisomerase III [Enterococcus faecalis].	30.20	702	418	23	3	654	4	683	4e-73	262
rs:WP_028545721	DNA topoisomerase III [Paenibacillus taiwanensis].	28.47	685	420	20	3	654	4	651	4e-73	261
rs:WP_045498250	DNA topoisomerase III [Vibrio sp. 151112A].	29.79	621	379	14	2	581	3	607	4e-73	260
tr:A0A060NIK4_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.99	669	379	25	3	611	10	662	4e-73	265
rs:WP_035234763	DNA topoisomerase III [Alcanivorax sp. 19-m-6].	29.20	654	413	15	1	614	1	644	4e-73	262
tr:J4W6P3_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.93	521	302	12	61	571	14	507	4e-73	257
tr:A0A061Q7A3_9VIBR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.56	583	362	14	32	581	14	592	4e-73	260
rs:WP_010730827	DNA topoisomerase III [Enterococcus faecalis].	29.67	664	395	19	2	644	5	617	4e-73	261
rs:WP_002366910	DNA topoisomerase III [Enterococcus faecalis].	29.52	664	396	19	2	644	5	617	4e-73	261
rs:WP_043541241	DNA topoisomerase III [Achromobacter sp. RTa].	29.34	726	427	24	3	675	5	697	4e-73	265
rs:WP_027642235	DNA topoisomerase III [[Clostridium] clostridioforme].	29.64	658	408	19	3	627	4	639	4e-73	262
rs:WP_001094103	DNA topoisomerase III, partial [Bacillus cereus].	31.90	583	354	16	3	554	4	574	4e-73	258
rs:WP_010771366	DNA topoisomerase III [Enterococcus caccae].	30.72	625	373	17	2	611	5	584	4e-73	261
rs:WP_028902015	DNA topoisomerase I [Prevotella corporis].	29.36	705	435	21	4	673	5	681	5e-73	261
rs:WP_021824923	DNA topoisomerase [Prevotella salivae].	28.02	721	449	19	1	676	1	696	5e-73	262
rs:WP_042583917	DNA topoisomerase III [Burkholderia sp. MSHR3999].	29.06	616	400	15	1	587	1	608	5e-73	261
tr:E2YTF1_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.82	664	394	19	2	644	61	673	5e-73	262
rs:WP_036640886	DNA topoisomerase III [Paenibacillus sp. FSL R5-808].	29.65	634	395	16	3	615	4	607	5e-73	261
rs:WP_000197427	DNA topoisomerase III [Vibrio cholerae].	30.65	620	375	16	2	581	3	607	5e-73	260
rs:WP_043357816	hypothetical protein, partial [Cupriavidus basilensis].	28.34	674	429	19	1	631	1	663	5e-73	260
rs:WP_009875554	DNA topoisomerase III [Actinobacillus pleuropneumoniae].	30.61	637	401	17	1	606	1	627	5e-73	260
tr:L2MPF4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.37	619	376	16	41	644	3	581	5e-73	260
rs:WP_019451929	DNA topoisomerase III [Cupriavidus sp. BIS7].	29.03	720	443	21	3	678	5	700	5e-73	265
rs:WP_014064994	DNA topoisomerase III [Haemophilus parainfluenzae].	29.00	662	418	17	1	629	1	643	5e-73	261
tr:L8U5T5_AGGAC	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.56	625	374	18	1	581	1	609	5e-73	260
rs:WP_005607634	DNA topoisomerase III [Actinobacillus pleuropneumoniae].	30.61	637	401	17	1	606	1	627	5e-73	260
rs:WP_018026660	hypothetical protein [Oligella urethralis].	29.86	730	431	26	3	681	5	704	5e-73	264
rs:WP_042351153	DNA topoisomerase III [Bacillus sp. G2(2012b)].	31.28	649	400	17	3	627	5	631	5e-73	261
rs:WP_022584315	DNA topoisomerase III [Brevibacillus laterosporus].	28.73	717	463	18	1	676	1	710	5e-73	262
rs:WP_038884305	DNA topoisomerase III [Vibrio rotiferianus].	29.90	612	390	14	2	581	3	607	5e-73	260
rs:WP_013390829	DNA topoisomerase III [Achromobacter xylosoxidans].	29.74	723	428	25	3	675	5	697	5e-73	264
rs:WP_005617231	DNA topoisomerase III [Actinobacillus pleuropneumoniae].	30.61	637	401	17	1	606	1	627	5e-73	259
tr:Q4QPE8_HAEI8	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.90	661	420	15	1	629	6	648	5e-73	261
tr:E0GLT5_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.82	664	394	19	2	644	61	673	5e-73	262
tr:E0GCU2_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.82	664	394	19	2	644	61	673	5e-73	262
rs:WP_033657898	DNA topoisomerase III [Enterococcus faecalis].	29.52	664	396	19	2	644	5	617	5e-73	261
rs:WP_036857289	DNA topoisomerase I [Prevotella denticola].	29.10	701	434	19	3	673	4	671	5e-73	261
rs:WP_009520786	DNA topoisomerase III [Ralstonia sp. PBA].	30.38	711	431	23	3	673	5	691	5e-73	264
rs:WP_024702582	DNA topoisomerase III [Vibrio parahaemolyticus].	30.18	613	387	15	2	581	3	607	6e-73	260
rs:WP_021441660	DNA topoisomerase III [Pseudomonas sp. EGD-AK9].	29.28	642	404	18	1	611	1	623	6e-73	260
rs:WP_036730954	DNA topoisomerase III [Paenibacillus sp. FSL R7-277].	30.14	637	388	16	3	615	4	607	6e-73	261
rs:WP_000088631	DNA topoisomerase III [Vibrio sp. RC586].	30.65	620	375	16	2	581	3	607	6e-73	260
rs:WP_032471176	DNA topoisomerase III [Vibrio cholerae].	30.65	620	375	16	2	581	3	607	6e-73	260
rs:WP_011053526	hypothetical protein [Haemophilus influenzae].	28.10	758	454	22	1	682	1	743	6e-73	262
rs:WP_017921309	DNA topoisomerase III [Burkholderia gladioli].	29.88	723	435	22	3	680	5	700	6e-73	264
tr:A0A078BQ75_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.25	630	418	12	1	611	1	615	6e-73	261
tr:L9UC23_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.55	626	401	15	1	602	29	638	6e-73	260
tr:A0A080KKI8_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.91	618	380	19	2	581	8	616	6e-73	259
rs:WP_002378482	DNA topoisomerase III [Enterococcus faecalis].	29.67	664	395	19	2	644	5	617	6e-73	261
rs:WP_005231974	DNA topoisomerase [Enterococcus casseliflavus].	29.86	720	458	20	3	686	4	712	6e-73	261
rs:WP_000197442	DNA topoisomerase III [Vibrio cholerae].	30.16	620	378	15	2	581	3	607	6e-73	260
rs:WP_039858283	DNA topoisomerase III [Halomonas titanicae].	29.55	626	401	15	1	602	1	610	6e-73	259
rs:WP_021014746	DNA topoisomerase III [Serratia sp. ATCC 39006].	28.27	658	430	15	1	629	1	645	6e-73	260
rs:WP_044478705	DNA topoisomerase III, partial [Peptoclostridium difficile].	33.02	530	315	15	1	511	1	509	6e-73	256
rs:WP_019413664	hypothetical protein [Paenisporosarcina sp. TG20].	29.03	713	457	20	3	681	4	701	6e-73	261
rs:WP_007173277	DNA topoisomerase I [Prevotella bergensis].	29.40	704	433	20	1	673	2	672	6e-73	261
rs:WP_010720799	DNA topoisomerase III, partial [Enterococcus hirae].	30.73	589	353	15	41	614	3	551	6e-73	260
rs:WP_046126935	DNA topoisomerase III [Vibrio cholerae].	30.48	620	376	16	2	581	3	607	6e-73	259
rs:WP_014430656	DNA topoisomerase III [Rubrivivax gelatinosus].	29.09	739	445	25	3	680	5	725	6e-73	264
tr:R4EG70_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.37	619	376	16	41	644	3	581	7e-73	260
rs:WP_004663540	DNA topoisomerase III [Pseudomonas savastanoi].	28.29	661	426	16	1	629	1	645	7e-73	260
rs:WP_046955042	DNA topoisomerase III [Bacillus cereus].	29.80	708	432	18	1	661	1	690	7e-73	261
rs:WP_036870016	DNA topoisomerase I [Prevotella histicola].	29.93	695	434	19	4	673	5	671	7e-73	261
rs:WP_015856075	DNA topoisomerase III [Ralstonia pickettii].	29.92	712	434	22	3	673	5	692	7e-73	264
rs:WP_039446882	DNA topoisomerase I [Porphyromonas gulae].	30.16	703	430	22	1	673	1	672	7e-73	261
gpu:CP011020_4761	DNA topoisomerase III [Pseudomonas chlororaphis]	27.16	670	440	17	1	638	1	654	7e-73	260
rs:WP_021752614	DNA topoisomerase III [Gemella bergeri].	29.66	654	404	18	3	634	4	623	7e-73	261
rs:WP_000197434	DNA topoisomerase III [Vibrio cholerae].	30.65	620	375	16	2	581	3	607	7e-73	259
rs:WP_019844491	DNA topoisomerase III [Dickeya zeae].	28.14	661	426	17	1	629	1	644	7e-73	260
rs:WP_027335540	DNA topoisomerase III [Halomonas sp. HL-48].	29.57	602	392	12	1	581	1	591	7e-73	259
rs:WP_025097237	DNA topoisomerase III [Burkholderia sp. A1].	29.74	723	436	22	3	680	5	700	7e-73	264
rs:WP_035921612	hypothetical protein, partial [Legionella moravica].	29.48	648	407	18	1	615	1	631	7e-73	259
rs:WP_002163405	DNA topoisomerase III [Bacillus cereus].	30.52	698	442	19	2	676	4	681	7e-73	261
rs:WP_008157627	DNA topoisomerase III [Achromobacter arsenitoxydans].	29.00	731	433	22	3	680	5	702	7e-73	264
rs:WP_004628306	DNA topoisomerase III [Ralstonia pickettii].	29.92	712	434	22	3	673	5	692	7e-73	264
rs:WP_046923262	DNA topoisomerase III [Lactobacillus ruminis].	30.13	677	391	19	2	648	3	627	7e-73	261
rs:WP_003342705	DNA topoisomerase III [Brevibacillus laterosporus].	28.65	719	461	18	1	676	1	710	7e-73	262
rs:WP_028129876	DNA topoisomerase [Selenomonas sp. AE3005].	28.63	709	445	20	1	665	1	692	7e-73	263
rs:WP_043944901	DNA topoisomerase III [Ralstonia solanacearum].	29.59	713	437	22	3	673	5	694	7e-73	264
rs:WP_034538694	DNA topoisomerase III [Carnobacterium inhibens].	29.20	709	459	16	2	680	3	698	7e-73	261
rs:WP_016088351	DNA topoisomerase III [Bacillus cereus].	29.94	708	431	18	1	661	1	690	7e-73	261
rs:WP_013666927	DNA topoisomerase III [Sphingobacterium sp. 21].	32.41	614	366	21	1	583	1	596	7e-73	259
rs:WP_042590295	DNA topoisomerase III [Ralstonia solanacearum].	29.59	713	437	22	3	673	5	694	7e-73	264
rs:WP_012436841	MULTISPECIES: DNA topoisomerase III [Ralstonia].	29.92	712	434	22	3	673	5	692	7e-73	264
rs:WP_039980581	DNA topoisomerase III [Vibrio sagamiensis].	29.85	613	389	14	2	581	3	607	7e-73	259
rs:WP_022053972	DNA topoisomerase III [Bacteroides plebeius CAG:211].	30.95	643	395	13	1	603	1	634	7e-73	261
rs:WP_021026750	DNA topoisomerase III [Comamonas sp. B-9].	30.81	675	372	24	3	611	5	650	8e-73	265
tr:G5GKN4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.23	558	331	13	41	587	1	533	8e-73	256
rs:WP_034700637	DNA topoisomerase III [Enterococcus hirae].	30.73	589	353	15	41	614	3	551	8e-73	259
rs:WP_035357163	ATP-dependent DNA helicase RecQ [Edaphobacter aggregans].	30.45	624	376	14	4	581	11	622	8e-73	267
tr:D4QJS4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.37	619	376	16	41	644	3	581	8e-73	259
rs:WP_028303988	DNA topoisomerase III [Oceanospirillum maris].	30.25	638	371	14	1	581	1	621	8e-73	259
rs:WP_013207290	DNA topoisomerase III [Ralstonia solanacearum].	29.59	713	437	22	3	673	5	694	8e-73	264
rs:WP_046121448	DNA topoisomerase III [Vibrio cholerae].	30.00	620	379	15	2	581	3	607	8e-73	259
rs:WP_032477814	DNA topoisomerase III [Vibrio cholerae].	30.65	620	375	16	2	581	3	607	8e-73	259
rs:WP_009239400	MULTISPECIES: DNA topoisomerase III [Ralstonia].	29.92	712	434	22	3	673	5	692	8e-73	264
rs:WP_009263227	DNA topoisomerase III [Lachnospiraceae bacterium 9_1_43BFAA].	29.57	690	445	17	1	669	1	670	8e-73	261
rs:WP_014618279	DNA topoisomerase III [Ralstonia solanacearum].	29.59	713	437	22	3	673	5	694	8e-73	264
rs:WP_034301545	DNA topoisomerase III [Bacillus sp. FJAT-14515].	28.47	713	471	15	3	681	2	709	8e-73	261
rs:WP_002171395	DNA topoisomerase III [Bacillus cereus].	30.34	712	423	19	1	661	1	690	8e-73	261
rs:WP_024977063	DNA topoisomerase III [Ralstonia pickettii].	29.92	712	434	22	3	673	5	692	8e-73	264
rs:WP_031415725	DNA topoisomerase III [Vibrio parahaemolyticus].	29.41	612	393	12	2	581	3	607	8e-73	259
rs:WP_033674734	DNA topoisomerase III [Bacillus gaemokensis].	31.68	606	363	14	1	573	1	588	8e-73	261
rs:WP_022477608	DNA topoisomerase [Coraliomargarita sp. CAG:312].	30.52	724	419	25	2	677	3	690	8e-73	263
rs:WP_007201190	DNA topoisomerase III [Fictibacillus macauensis].	29.82	721	446	23	1	676	1	706	9e-73	261
rs:WP_017012778	DNA topoisomerase III [Enterovibrio calviensis].	31.26	611	379	15	2	581	3	603	9e-73	259
rs:WP_040313084	DNA topoisomerase III [Bacteroides plebeius].	30.90	644	394	15	1	603	1	634	9e-73	261
rs:WP_039575248	DNA topoisomerase III [Xanthomonas axonopodis].	28.95	646	403	16	1	611	1	625	9e-73	260
rs:WP_003264700	DNA topoisomerase III [Ralstonia solanacearum].	29.59	713	437	22	3	673	5	694	9e-73	264
tr:V2C251_SALET	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.43	555	332	19	1	523	1	544	9e-73	258
tr:E0GRL9_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.30	627	373	16	2	611	61	640	9e-73	261
rs:WP_017012090	DNA topoisomerase III [Enterovibrio calviensis].	31.59	611	377	16	2	581	3	603	9e-73	259
tr:A0A0D6ZHR8_LACDE	SubName: Full=Topoisomerase I {ECO:0000313|EMBL:KIY24168.1};	28.04	724	447	19	3	676	4	703	9e-73	261
rs:WP_005604263	DNA topoisomerase III [Actinobacillus pleuropneumoniae].	30.61	637	401	17	1	606	1	627	9e-73	259
tr:A0A078BHB1_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.98	635	409	15	1	611	57	673	9e-73	262
tr:S4G1Y5_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.82	664	394	19	2	644	61	673	9e-73	261
rs:WP_039451807	DNA topoisomerase I [Pedobacter glucosidilyticus].	29.87	616	386	16	1	589	1	597	9e-73	258
rs:WP_027815887	DNA topoisomerase III [Burkholderia bannensis].	29.83	714	431	21	3	673	5	691	9e-73	264
tr:A9L6T8_SHEB9	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.50	623	373	19	1	579	1	607	9e-73	260
rs:WP_019332795	DNA topoisomerase III [Pseudomonas syringae].	28.96	663	419	16	1	629	1	645	9e-73	260
tr:S4BMI7_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.82	664	394	19	2	644	61	673	9e-73	261
rs:WP_043816567	DNA topoisomerase III [Rubrivivax gelatinosus].	29.09	739	445	25	3	680	5	725	9e-73	263
tr:E6J286_STRAP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.04	564	314	16	46	587	2	529	1e-72	256
rs:WP_046514894	DNA topoisomerase III [Bacillus sp. SA1-12].	29.30	703	442	18	1	661	1	690	1e-72	261
rs:WP_002053203	DNA topoisomerase III [Vibrio cholerae].	30.32	620	377	15	2	581	3	607	1e-72	259
rs:WP_004560848	DNA topoisomerase [Lactobacillus delbrueckii].	28.21	709	465	19	3	676	4	703	1e-72	261
rs:WP_037072304	DNA topoisomerase III [Psychromonas arctica].	31.27	614	370	15	1	578	1	598	1e-72	259
rs:WP_032599027	DNA topoisomerase I [Bacteroides fragilis].	28.17	678	434	17	1	650	1	653	1e-72	260
tr:L2R3E3_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.26	618	378	16	41	644	3	581	1e-72	259
rs:WP_003267350	DNA topoisomerase III [Ralstonia solanacearum].	29.59	713	437	22	3	673	5	694	1e-72	263
rs:WP_022523733	DNA topoisomerase III [Halomonas sp. A3H3].	29.23	626	403	13	1	602	1	610	1e-72	259
rs:WP_006208277	DNA topoisomerase III [Paenibacillus vortex].	29.65	634	395	16	3	615	4	607	1e-72	261
rs:WP_043063478	DNA topoisomerase III [Aneurinibacillus migulanus].	28.78	674	410	21	3	646	4	637	1e-72	261
rs:WP_011876105	DNA topoisomerase [Burkholderia vietnamiensis].	29.85	737	436	23	3	680	5	719	1e-72	264
tr:S4D4N9_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.02	603	365	15	28	614	5	566	1e-72	259
rs:WP_024894057	DNA topoisomerase III [Acidithiobacillus thiooxidans].	29.46	645	391	15	1	610	1	616	1e-72	259
rs:WP_035578786	DNA topoisomerase III [Halomonas sp. TG39a].	28.66	642	406	13	1	612	1	620	1e-72	259
tr:A0A099MYA2_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.94	637	421	14	1	614	1	622	1e-72	259
rs:WP_023464545	DNA topoisomerase III [Pseudomonas aeruginosa].	28.08	666	421	17	1	629	1	645	1e-72	259
rs:WP_002044380	DNA topoisomerase III [Vibrio cholerae].	30.48	620	376	16	2	581	3	607	1e-72	259
rs:WP_035236464	ATP-dependent DNA helicase RecQ, partial [Acidobacteriaceae bacterium URHE0068].	29.38	640	364	15	4	579	19	634	1e-72	263
rs:WP_041048795	DNA topoisomerase III [Vibrio cholerae].	30.32	620	377	15	2	581	3	607	1e-72	259
tr:J1BJU3_STREE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.66	528	306	11	65	580	16	516	1e-72	256
rs:WP_033082620	DNA topoisomerase III [Colwellia psychrerythraea].	30.60	621	374	18	1	576	1	609	1e-72	259
rs:WP_001959922	DNA topoisomerase III [Vibrio cholerae].	30.48	620	376	16	2	581	3	607	1e-72	259
rs:WP_033480338	DNA topoisomerase, partial [Xanthomonas axonopodis].	27.91	609	394	18	68	639	2	602	1e-72	258
rs:WP_043947600	DNA topoisomerase III [Ralstonia solanacearum].	29.59	713	437	22	3	673	5	694	1e-72	263
rs:WP_044910184	hypothetical protein, partial [Lachnospiraceae bacterium MC2017].	32.49	631	357	21	3	578	4	620	1e-72	259
rs:WP_002364251	DNA topoisomerase III [Enterococcus faecalis].	29.67	664	395	19	2	644	5	617	1e-72	260
rs:WP_000766732	DNA topoisomerase III [Bacillus thuringiensis].	30.47	709	426	18	1	661	1	690	1e-72	260
rs:WP_013795485	DNA topoisomerase III [Marinomonas posidonica].	31.30	623	387	15	1	591	1	614	1e-72	259
rs:WP_013972307	DNA topoisomerase III [Pseudomonas putida].	28.08	641	415	14	1	614	1	622	1e-72	259
rs:WP_006299012	DNA topoisomerase III [Hylemonella gracilis].	28.73	738	450	22	3	681	4	724	1e-72	265
rs:WP_027669479	DNA topoisomerase III [Rheinheimera baltica].	28.96	618	396	13	1	581	1	612	1e-72	259
rs:WP_033928704	DNA topoisomerase III [Vibrio cholerae].	30.48	620	376	16	2	581	3	607	1e-72	259
rs:WP_016249872	DNA topoisomerase III [Enterococcus casseliflavus].	29.45	713	470	15	3	686	4	712	1e-72	261
rs:WP_017020022	DNA topoisomerase III [Aliivibrio fischeri].	30.27	621	369	16	2	574	12	616	1e-72	259
rs:WP_035987223	DNA topoisomerase III [Burkholderia caribensis].	29.82	721	438	22	3	680	5	700	1e-72	263
rs:WP_025638623	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	612	395	12	2	581	3	607	1e-72	259
rs:WP_042184736	DNA topoisomerase III [Paenibacillus sp. FSL H7-0737].	29.13	635	396	16	3	615	4	606	1e-72	260
tr:R3I7T2_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.37	619	376	16	41	644	3	581	1e-72	259
rs:WP_004302894	DNA topoisomerase III [Thauera aminoaromatica].	29.45	730	439	24	2	682	4	706	1e-72	263
rs:WP_010737146	MULTISPECIES: DNA topoisomerase III, partial [Enterococcus].	30.73	589	353	15	41	614	3	551	1e-72	259
tr:L2QP66_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.42	618	377	15	41	644	3	581	1e-72	259
rs:WP_029197378	DNA topoisomerase III [Paenibacillus alginolyticus].	30.65	659	384	22	3	627	4	623	1e-72	260
rs:WP_044278434	ATP-dependent DNA helicase RecQ [Myxococcus stipitatus].	28.37	638	387	14	4	578	27	657	1e-72	268
rs:WP_000197428	DNA topoisomerase III [Vibrio cholerae].	30.00	620	379	15	2	581	3	607	1e-72	259
rs:WP_025633667	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	1e-72	259
rs:WP_036509820	DNA topoisomerase III [Nitrincola sp. AK23].	30.25	628	371	18	1	581	1	608	1e-72	259
rs:WP_012093963	DNA topoisomerase III [Bacillus cytotoxicus].	31.87	593	379	13	1	573	1	588	1e-72	260
rs:WP_000197429	DNA topoisomerase III [Vibrio cholerae].	30.32	620	377	15	2	581	3	607	1e-72	259
rs:WP_016627352	DNA topoisomerase [Enterococcus faecalis].	30.20	702	418	23	3	654	4	683	1e-72	260
rs:WP_006005546	DNA topoisomerase III [Glaciecola punicea].	31.00	613	379	14	1	581	1	601	1e-72	258
rs:WP_047039718	DNA topoisomerase III [Enterobacter aerogenes].	29.37	606	391	14	1	581	1	594	1e-72	258
rs:WP_029046468	DNA topoisomerase III [Cupriavidus sp. amp6].	29.57	717	440	22	3	677	5	698	1e-72	263
rs:WP_046112814	DNA topoisomerase III [Aquincola tertiaricarbonis].	29.63	739	426	28	3	673	5	717	1e-72	263
rs:WP_021205167	DNA topoisomerase III [Pseudomonas aeruginosa].	28.68	659	425	16	1	629	1	644	2e-72	259
rs:WP_042988236	DNA topoisomerase III [Vibrio cholerae].	30.32	620	377	15	2	581	3	607	2e-72	259
rs:WP_041929814	DNA topoisomerase III [Methylibium petroleiphilum].	29.32	730	439	24	3	673	5	716	2e-72	263
rs:WP_032567528	DNA topoisomerase I [Bacteroides fragilis].	29.60	706	441	22	1	676	1	680	2e-72	260
rs:WP_045042815	DNA topoisomerase III [Photobacterium kishitanii].	31.54	615	370	20	3	581	4	603	2e-72	259
tr:A0A078RFF4_BACVU	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:KDS33481.1};	28.25	669	447	13	29	676	12	668	2e-72	259
rs:WP_011609464	DNA topoisomerase III [Histophilus somni].	31.77	620	376	18	1	585	1	608	2e-72	258
rs:WP_033892104	DNA topoisomerase III [Bifidobacterium saguini].	26.75	729	473	21	1	684	1	713	2e-72	260
tr:B5D0F1_BACPM	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EDY94995.1};	30.90	644	394	15	1	603	32	665	2e-72	261
rs:WP_038568657	DNA topoisomerase III [Paenibacillus odorifer].	28.98	635	397	15	3	615	4	606	2e-72	260
rs:WP_042983184	DNA topoisomerase III [Bacillus mycoides].	29.84	707	433	18	1	661	1	690	2e-72	260
tr:L7TZD2_MYXSD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.37	638	387	14	4	578	32	662	2e-72	268
rs:WP_044024448	DNA topoisomerase III [Actinobacillus ureae].	30.97	649	383	20	1	606	1	627	2e-72	258
rs:WP_041228250	DNA topoisomerase III [Cupriavidus necator].	29.43	717	441	22	3	677	5	698	2e-72	263
tr:U6S1R1_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.67	664	395	19	2	644	61	673	2e-72	261
rs:WP_004322053	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	30.21	705	432	25	1	676	1	674	2e-72	260
rs:WP_035817413	DNA topoisomerase III [Cupriavidus sp. SK-4].	29.39	718	440	23	3	677	5	698	2e-72	263
rs:WP_002192122	DNA topoisomerase III [Bacillus cereus].	30.12	684	409	15	41	673	42	707	2e-72	260
rs:WP_025910233	DNA topoisomerase III [Bacillus flexus].	29.48	658	409	17	3	646	4	620	2e-72	259
rs:WP_002170059	DNA topoisomerase III [Bacillus cereus].	30.12	684	409	15	41	673	42	707	2e-72	260
tr:G9EQA5_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.95	677	429	19	1	642	1	660	2e-72	259
rs:WP_016274760	DNA topoisomerase III [Bacteroides massiliensis].	28.23	712	457	21	1	683	1	687	2e-72	259
rs:WP_006037718	DNA topoisomerase III [Paenibacillus curdlanolyticus].	28.77	709	414	20	3	657	4	675	2e-72	261
rs:WP_005638126	conjugal transfer protein TraE [Haemophilus haemolyticus].	28.25	761	449	24	1	682	1	743	2e-72	261
rs:WP_000766741	DNA topoisomerase III [Bacillus thuringiensis].	30.32	709	427	18	1	661	1	690	2e-72	260
rs:WP_022100017	DNA topoisomerase [Proteobacteria bacterium CAG:139].	29.54	721	425	26	3	673	5	692	2e-72	262
rs:WP_016295879	DNA topoisomerase III [Lachnospiraceae bacterium M18-1].	28.38	680	422	17	1	647	1	648	2e-72	259
rs:WP_000766737	DNA topoisomerase III [Bacillus cereus].	30.23	708	429	18	1	661	1	690	2e-72	260
rs:WP_039971892	DNA topoisomerase III [Brevibacillus agri].	31.01	661	395	20	3	627	5	640	2e-72	260
rs:WP_029839225	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	2e-72	259
rs:WP_045044901	DNA topoisomerase III [Photobacterium kishitanii].	31.54	615	370	20	3	581	4	603	2e-72	258
rs:WP_007132739	DNA topoisomerase III [Paenibacillus lactis].	29.56	636	394	16	3	615	4	608	2e-72	260
rs:WP_028470948	DNA topoisomerase III [Neptunomonas japonica].	30.27	621	386	16	1	581	1	614	2e-72	258
rs:WP_006305756	DNA topoisomerase TopB [Centipeda periodontii].	26.75	684	418	21	1	630	1	655	2e-72	260
rs:WP_025335202	DNA topoisomerase III [Paenibacillus sabinae].	28.55	753	431	26	3	673	4	731	2e-72	261
rs:WP_011299539	DNA topoisomerase III [Cupriavidus pinatubonensis].	29.71	717	439	22	3	677	5	698	2e-72	263
rs:WP_008917977	DNA topoisomerase III [Burkholderia sp. H160].	30.17	716	430	22	3	675	5	693	2e-72	263
rs:WP_019029803	DNA topoisomerase III [Colwellia piezophila].	31.34	619	368	17	1	574	1	607	2e-72	258
rs:WP_036668403	DNA topoisomerase III [Paenibacillus sp. FSL R5-192].	28.80	684	421	21	3	659	4	648	2e-72	260
rs:WP_013699754	DNA topoisomerase III [Burkholderia gladioli].	29.74	723	436	22	3	680	5	700	2e-72	263
rs:WP_012431376	DNA topoisomerase III [Burkholderia phytofirmans].	29.97	714	430	21	3	673	5	691	2e-72	263
rs:WP_029802080	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	2e-72	258
rs:WP_032479936	DNA topoisomerase III [Vibrio cholerae].	30.48	620	376	16	2	581	3	607	2e-72	258
rs:WP_039597233	DNA topoisomerase III [Ralstonia sp. A12].	29.83	714	432	22	3	673	5	692	2e-72	263
rs:WP_036048796	MULTISPECIES: DNA topoisomerase III [Burkholderia].	29.74	723	436	22	3	680	5	700	2e-72	263
rs:WP_027793206	DNA topoisomerase III [Burkholderia acidipaludis].	29.97	714	430	21	3	673	5	691	2e-72	263
tr:B3GXI1_ACTP7	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.46	637	402	17	1	606	8	634	2e-72	258
rs:WP_016626025	DNA topoisomerase [Enterococcus faecalis].	30.20	702	418	23	3	654	4	683	2e-72	260
rs:WP_000197433	DNA topoisomerase III [Vibrio cholerae].	30.48	620	376	16	2	581	3	607	2e-72	258
rs:WP_028043112	DNA topoisomerase III [Candidatus Stoquefichus massiliensis].	29.61	662	396	20	3	627	5	633	2e-72	260
tr:C3QRJ0_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.33	641	420	13	54	676	6	631	2e-72	258
rs:WP_036894232	DNA topoisomerase I [Prevotella sp. S7-1-8].	30.22	718	410	26	4	673	5	679	2e-72	259
rs:WP_044396211	DNA topoisomerase III [Acidovorax temperans].	29.61	726	427	24	3	666	5	708	2e-72	264
rs:WP_047299168	DNA topoisomerase III [Bifidobacterium bifidum].	27.83	751	444	22	1	679	1	725	2e-72	260
rs:WP_025001427	DNA topoisomerase I [Prevotella aurantiaca].	29.77	692	439	19	4	673	5	671	2e-72	259
rs:WP_000766779	DNA topoisomerase III [Bacillus cereus].	29.66	708	433	18	1	661	1	690	2e-72	260
tr:L5MM22_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	30.95	656	402	19	3	627	10	645	2e-72	260
rs:WP_004581684	DNA topoisomerase III [Marinobacter nanhaiticus].	27.84	643	423	15	1	614	1	631	2e-72	260
tr:E6FP47_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.52	664	396	19	2	644	61	673	2e-72	260
rs:WP_007938669	MULTISPECIES: DNA topoisomerase III [Pelosinus].	30.27	664	410	19	1	629	1	646	2e-72	258
rs:WP_021677873	DNA topoisomerase [Porphyromonas gingivalis].	29.91	702	432	22	1	673	2	672	2e-72	259
rs:WP_035711184	hypothetical protein, partial [Bacillus aidingensis].	29.71	700	443	20	3	673	4	683	2e-72	259
rs:WP_017867276	DNA topoisomerase III [Lactobacillus pobuzihii].	30.18	623	377	15	2	610	3	581	2e-72	259
rs:WP_004560603	DNA topoisomerase [Lactobacillus delbrueckii].	27.90	724	448	19	3	676	4	703	2e-72	259
rs:WP_026045275	DNA topoisomerase III [Burkholderia pyrrocinia].	29.41	714	434	22	3	673	5	691	2e-72	263
tr:X2H3M2_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.12	617	380	19	2	581	8	616	2e-72	258
rs:WP_034374893	DNA topoisomerase III [Comamonas testosteroni].	29.59	730	424	24	3	666	5	710	2e-72	264
tr:A6W0F1_MARMS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.77	655	415	17	1	622	1	643	2e-72	259
rs:WP_036039160	DNA topoisomerase III [Burkholderia gladioli].	29.69	714	432	21	3	673	5	691	2e-72	263
rs:WP_006011047	DNA topoisomerase III [Glaciecola pallidula].	31.00	613	379	16	1	581	1	601	2e-72	258
rs:WP_031828430	DNA topoisomerase III [Vibrio parahaemolyticus].	29.89	649	399	19	1	617	1	625	2e-72	259
rs:WP_000766780	DNA topoisomerase III [Bacillus cereus].	29.66	708	433	18	1	661	1	690	2e-72	259
rs:WP_025546308	DNA topoisomerase III [Vibrio parahaemolyticus].	30.07	612	389	14	2	581	3	607	2e-72	258
rs:WP_025503057	DNA topoisomerase III [Vibrio parahaemolyticus].	30.07	612	389	14	2	581	3	607	2e-72	258
tr:D4WMC6_BACOV	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.33	641	420	13	54	676	6	631	2e-72	258
tr:W7ZP94_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.18	651	401	20	2	627	4	632	2e-72	260
rs:WP_032480933	DNA topoisomerase III [Vibrio cholerae].	30.48	620	376	16	2	581	3	607	2e-72	258
rs:WP_006556936	DNA topoisomerase III [Veillonella ratti].	29.11	639	388	13	1	581	1	632	2e-72	261
tr:A2SCD8_METPP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.32	730	439	24	3	673	21	732	2e-72	263
rs:WP_045607374	DNA topoisomerase III [Vibrio parahaemolyticus].	30.07	612	389	14	2	581	3	607	3e-72	258
rs:WP_005801814	DNA topoisomerase I [Bacteroides fragilis].	27.83	697	465	14	1	676	1	680	3e-72	259
rs:WP_029864161	DNA topoisomerase III [Vibrio parahaemolyticus].	29.41	612	393	12	2	581	3	607	3e-72	258
rs:WP_044904480	DNA topoisomerase III, partial [Lachnospiraceae bacterium 3-2].	30.94	585	368	12	105	673	2	566	3e-72	257
rs:WP_039163724	DNA topoisomerase III [Gallibacterium anatis].	28.19	642	415	13	1	614	1	624	3e-72	259
rs:WP_047298255	DNA topoisomerase III [Bifidobacterium bifidum].	27.88	746	450	22	1	679	1	725	3e-72	260
tr:A0A0D6EA40_9GAMM	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:CEP36445.1};	28.66	642	406	13	1	612	1	620	3e-72	258
rs:WP_023466257	DNA topoisomerase [Lactobacillus fermentum].	30.21	725	440	24	3	676	4	713	3e-72	259
tr:A3N0A8_ACTP2	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.46	637	402	17	1	606	8	634	3e-72	258
rs:WP_036889711	DNA topoisomerase I [Porphyromonas crevioricanis].	29.60	706	420	19	4	673	5	669	3e-72	259
rs:WP_034691397	DNA topoisomerase III [Acidovorax sp. MR-S7].	28.77	664	418	17	1	629	1	644	3e-72	258
rs:WP_025591399	DNA topoisomerase III [Vibrio parahaemolyticus].	29.25	612	394	12	2	581	3	607	3e-72	258
rs:WP_005653577	DNA topoisomerase III [Haemophilus influenzae].	29.24	643	409	15	1	615	1	625	3e-72	259
rs:WP_038518007	DNA topoisomerase III, partial [Gilliamella apicola].	31.12	617	380	19	2	581	8	616	3e-72	258
rs:WP_000766759	DNA topoisomerase III [Bacillus cereus].	29.80	708	432	18	1	661	1	690	3e-72	259
rs:WP_015038895	DNA topoisomerase III [Bordetella parapertussis].	27.46	670	420	17	1	629	1	645	3e-72	258
rs:WP_035246216	hypothetical protein, partial [Desulfobulbus mediterraneus].	31.10	643	395	17	3	621	4	622	3e-72	258
rs:WP_031586293	DNA topoisomerase [Selenomonas bovis].	29.17	689	401	23	1	630	1	661	3e-72	261
rs:WP_025708278	DNA topoisomerase III [Paenibacillus graminis].	29.24	643	386	17	3	615	4	607	3e-72	259
rs:WP_038585649	DNA topoisomerase III [Paenibacillus sp. FSL H7-0357].	29.42	639	390	17	3	615	4	607	3e-72	259
rs:WP_029627393	DNA topoisomerase III [Vibrio cholerae].	29.52	620	382	14	2	581	3	607	3e-72	258
rs:WP_046575281	DNA topoisomerase III [Burkholderia gladioli].	29.74	723	436	22	3	680	5	700	3e-72	262
rs:WP_033466984	DNA topoisomerase III [Bordetella bronchiseptica].	29.49	729	432	25	3	680	5	702	3e-72	262
rs:WP_036549645	DNA topoisomerase III [Nitrincola lacisaponensis].	29.55	626	377	18	1	581	2	608	3e-72	258
rs:WP_041013332	DNA topoisomerase III [Pseudomonas xanthomarina].	27.40	668	423	17	1	629	1	645	3e-72	258
rs:WP_020878368	DNA topoisomerase III [Desulfococcus multivorans].	28.46	738	450	21	3	687	13	725	3e-72	263
rs:WP_042039942	DNA topoisomerase III [Aeromonas rivuli].	28.46	657	417	17	1	622	1	639	3e-72	258
rs:WP_000766742	DNA topoisomerase III [Bacillus cereus].	29.99	697	445	16	1	661	1	690	3e-72	259
tr:D0KM86_PECWW	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.73	637	411	15	5	614	1	621	3e-72	258
rs:WP_020230133	DNA topoisomerase III [Acidovorax sp. MR-S7].	28.77	664	418	17	1	629	26	669	3e-72	259
rs:WP_028820891	DNA topoisomerase III [beta proteobacterium SCGC AAA027-I06].	28.79	733	436	21	3	666	4	719	3e-72	263
rs:WP_006842135	DNA topoisomerase I [Dysgonomonas mossii].	29.59	713	435	20	4	677	5	689	3e-72	259
rs:WP_011770752	DNA topoisomerase III [Psychromonas ingrahamii].	30.94	614	379	14	1	581	1	602	3e-72	258
rs:WP_039016632	DNA topoisomerase III [Cupriavidus sp. SHE].	28.53	659	426	16	1	629	1	644	4e-72	258
rs:WP_018312052	DNA topoisomerase III [Cupriavidus sp. UYPR2.512].	29.25	718	441	23	3	677	5	698	4e-72	262
rs:WP_035434243	DNA topoisomerase III [Bacillus sp. UNC322MFChir4.1].	29.57	700	431	18	1	655	1	683	4e-72	259
rs:WP_043210668	DNA topoisomerase III [Bordetella hinzii].	29.75	726	424	24	3	675	5	697	4e-72	262
rs:WP_028197702	DNA topoisomerase III [Burkholderia fungorum].	30.36	718	422	24	3	673	5	691	4e-72	262
rs:WP_026504840	DNA topoisomerase III [Butyrivibrio sp. NC3005].	30.46	627	364	20	1	585	1	597	4e-72	257
rs:WP_018903490	DNA topoisomerase III [Variovorax paradoxus].	29.51	749	435	26	3	680	4	730	4e-72	263
rs:WP_019142232	DNA topoisomerase III [Herbaspirillum massiliense].	29.21	719	434	25	3	673	5	696	4e-72	262
rs:WP_041335059	DNA topoisomerase III [Bacillus subtilis].	30.71	700	431	24	3	679	4	672	4e-72	260
rs:WP_004374762	DNA topoisomerase I [Prevotella oris].	29.46	706	430	19	1	673	2	672	4e-72	259
rs:WP_008344184	DNA topoisomerase [Burkholderia sp. SJ98].	28.04	731	444	23	3	676	5	710	4e-72	261
rs:WP_026327811	DNA topoisomerase [Selenomonas bovis].	29.75	689	397	23	1	630	1	661	4e-72	261
rs:WP_036606074	DNA topoisomerase III [Paenibacillus sp. FSL H7-689].	28.40	683	425	20	3	659	4	648	4e-72	259
rs:WP_042626312	DNA topoisomerase III [Burkholderia glumae].	29.46	723	438	22	3	680	5	700	4e-72	262
rs:WP_034382965	DNA topoisomerase, partial [Comamonas testosteroni].	29.50	600	375	15	1	561	1	591	4e-72	259
rs:WP_013439876	DNA topoisomerase [Lactobacillus delbrueckii].	27.90	724	448	19	3	676	4	703	4e-72	259
rs:WP_035458073	DNA topoisomerase I [Bacteroides uniformis].	27.46	710	465	18	1	683	1	687	4e-72	259
rs:WP_025605522	DNA topoisomerase III [Vibrio parahaemolyticus].	29.74	612	391	13	2	581	3	607	4e-72	258
rs:WP_043741665	DNA topoisomerase III [Thauera sp. SWB20].	29.41	731	438	25	2	682	4	706	4e-72	261
rs:WP_019829398	DNA topoisomerase III [Vibrio cholerae].	29.84	620	380	15	2	581	3	607	4e-72	258
rs:WP_030102534	DNA topoisomerase III [Burkholderia sp. K24].	30.36	718	422	24	3	673	5	691	4e-72	262
rs:WP_000197435	DNA topoisomerase III [Vibrio cholerae].	29.84	620	380	15	2	581	3	607	4e-72	258
rs:WP_020229248	DNA topoisomerase III [Acidovorax sp. MR-S7].	30.84	668	380	25	3	611	5	649	4e-72	263
rs:WP_046921879	DNA topoisomerase III [Lactobacillus ruminis].	30.18	676	392	18	2	648	3	627	4e-72	258
rs:WP_039335056	hypothetical protein, partial [Burkholderia multivorans].	27.90	656	422	17	1	614	1	647	4e-72	258
rs:WP_005680137	MULTISPECIES: DNA topoisomerase I [Bacteroides].	29.51	627	410	12	68	676	2	614	4e-72	257
rs:WP_027199369	DNA topoisomerase III [Burkholderia sprentiae].	30.36	718	422	25	3	673	5	691	4e-72	262
rs:WP_034044103	DNA topoisomerase III [Pseudomonas aeruginosa].	28.64	667	421	19	1	629	1	650	4e-72	258
rs:WP_045205150	DNA topoisomerase III [Burkholderiaceae bacterium 26].	29.92	712	434	22	3	673	5	692	4e-72	262
rs:WP_007581951	MULTISPECIES: DNA topoisomerase III [Burkholderia].	29.54	721	440	22	3	680	5	700	5e-72	262
tr:T0VIC8_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.53	596	362	14	38	614	9	565	5e-72	258
rs:WP_045588151	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	5e-72	258
tr:L2R6Q6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.21	619	377	16	41	644	3	581	5e-72	258
rs:WP_035165068	topoisomerase I [Lactobacillus delbrueckii].	27.76	724	449	19	3	676	4	703	5e-72	259
rs:WP_002377042	DNA topoisomerase III [Enterococcus faecalis].	29.67	664	395	19	2	644	5	617	5e-72	258
rs:WP_041158384	DNA topoisomerase III [Halomonas sp. KHS3].	29.07	626	404	14	1	602	1	610	5e-72	257
rs:WP_017152229	DNA topoisomerase III [Bacillus sp. FJAT-13831].	31.94	598	372	14	1	573	1	588	5e-72	259
rs:WP_042907306	DNA topoisomerase III [Gallibacterium anatis].	28.19	642	415	13	1	614	1	624	5e-72	258
rs:WP_014590367	DNA topoisomerase III [Pseudomonas putida].	28.87	613	390	14	1	581	1	599	5e-72	257
rs:WP_041512402	DNA topoisomerase III [Nitrosospira sp. NpAV].	29.49	719	426	25	3	671	5	692	5e-72	261
rs:WP_040292887	DNA topoisomerase, partial [Acetonema longum].	28.64	646	412	18	1	615	1	628	5e-72	258
rs:WP_003696757	DNA topoisomerase III [Lactobacillus ruminis].	30.03	676	393	17	2	648	3	627	5e-72	258
rs:WP_019969023	DNA topoisomerase I [Prevotella maculosa].	29.39	735	432	27	1	677	1	706	5e-72	259
rs:WP_000766738	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.23	708	429	18	1	661	1	690	5e-72	259
rs:WP_028203227	DNA topoisomerase III [Burkholderia nodosa].	29.45	713	435	22	3	673	5	691	5e-72	261
rs:WP_011466216	DNA topoisomerase III [Rhodoferax ferrireducens].	28.48	755	443	27	3	680	4	738	5e-72	263
rs:WP_007856134	DNA topoisomerase III, partial [Acidovorax sp. CF316].	28.91	723	436	23	3	666	5	708	5e-72	262
rs:WP_027474744	DNA topoisomerase III [Curvibacter gracilis].	29.37	732	428	24	3	666	5	715	5e-72	263
rs:WP_025499560	DNA topoisomerase III [Vibrio parahaemolyticus].	29.25	612	394	12	2	581	3	607	5e-72	257
tr:E8KHI4_9PAST	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.82	649	384	20	1	606	8	634	5e-72	257
rs:WP_022280887	DNA topoisomerase [Lactobacillus ruminis CAG:367].	29.99	677	392	19	2	648	3	627	5e-72	258
rs:WP_041060515	DNA topoisomerase III [Jeotgalibacillus campisalis].	30.92	705	444	22	3	675	4	697	5e-72	258
rs:WP_025442128	DNA topoisomerase III [Vibrio parahaemolyticus].	29.25	612	394	12	2	581	3	607	5e-72	257
rs:WP_006233033	DNA topoisomerase III [Photobacterium profundum].	29.74	622	384	15	2	581	3	613	5e-72	257
rs:WP_013634106	DNA topoisomerase III [Pedobacter saltans].	29.51	610	389	14	1	583	1	596	6e-72	256
rs:WP_018362612	DNA topoisomerase I [Prevotella nanceiensis].	30.10	701	425	19	4	673	5	671	6e-72	258
rs:WP_022537063	DNA topoisomerase III [Ralstonia pickettii].	29.25	718	441	24	3	677	5	698	6e-72	262
rs:WP_009592313	DNA topoisomerase III [Paenibacillus sp. HGF5].	28.98	635	399	15	3	615	4	608	6e-72	258
rs:WP_003693017	DNA topoisomerase III [Lactobacillus ruminis].	30.03	676	393	17	2	648	3	627	6e-72	258
rs:WP_025628854	DNA topoisomerase III [Vibrio parahaemolyticus].	30.07	612	389	14	2	581	3	607	6e-72	257
rs:WP_000766778	DNA topoisomerase III [Bacillus cereus].	29.71	700	428	17	1	654	1	682	6e-72	259
rs:WP_007958677	DNA topoisomerase III [Pelosinus fermentans].	30.31	640	398	17	1	610	1	622	6e-72	257
rs:WP_043375951	DNA topoisomerase III [Comamonas testosteroni].	29.45	730	425	24	3	666	5	710	6e-72	263
rs:WP_003196873	MULTISPECIES: DNA topoisomerase III [Bacillus].	31.73	602	368	14	1	573	1	588	6e-72	258
rs:WP_000766740	DNA topoisomerase III [Bacillus thuringiensis].	29.94	708	431	17	1	661	1	690	6e-72	258
rs:WP_042883607	DNA topoisomerase III [Cupriavidus necator].	29.39	718	440	24	3	677	5	698	6e-72	262
rs:WP_025529541	DNA topoisomerase III [Vibrio parahaemolyticus].	29.25	612	394	12	2	581	3	607	6e-72	257
rs:WP_000766783	DNA topoisomerase III [Bacillus cereus].	29.94	708	431	17	1	661	1	690	6e-72	258
rs:WP_000766745	DNA topoisomerase III [Bacillus cereus].	30.23	708	429	18	1	661	1	690	6e-72	258
rs:WP_025541336	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	612	395	12	2	581	3	607	6e-72	257
rs:WP_031652706	DNA topoisomerase III [Pseudomonas aeruginosa].	28.64	667	421	19	1	629	1	650	6e-72	258
rs:WP_024633551	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	28.55	683	424	21	3	659	4	648	6e-72	258
rs:WP_025082441	DNA topoisomerase III [Lactobacillus fuchuensis].	30.76	621	376	14	2	610	4	582	6e-72	258
rs:WP_029831738	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	6e-72	257
tr:R9HYZ0_BACUN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOS06385.1};	27.46	710	465	18	1	683	30	716	6e-72	259
tr:Q21RE9_RHOFT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.80	757	438	27	3	680	19	753	6e-72	263
rs:WP_003060036	DNA topoisomerase III [Comamonas testosteroni].	29.45	730	425	24	3	666	5	710	6e-72	263
rs:WP_002086236	DNA topoisomerase III [Bacillus cereus].	30.04	719	416	19	1	661	1	690	6e-72	258
rs:WP_031778422	DNA topoisomerase III [Vibrio parahaemolyticus].	30.07	612	389	14	2	581	3	607	6e-72	257
rs:WP_041734236	DNA topoisomerase III [Burkholderia sp. CCGE1002].	29.97	714	430	22	3	673	5	691	6e-72	261
tr:D4VW42_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.10	618	379	16	41	644	3	581	6e-72	257
rs:WP_000766751	DNA topoisomerase III [Bacillus cereus].	29.52	708	421	17	1	655	1	683	6e-72	258
rs:WP_017447821	DNA topoisomerase III [Vibrio parahaemolyticus].	29.25	612	394	12	2	581	3	607	6e-72	257
tr:S4BBF3_ENTCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.73	602	368	15	28	614	5	566	6e-72	258
rs:WP_032856232	DNA topoisomerase I [Bacteroides ovatus].	29.35	627	411	12	68	676	2	614	6e-72	256
rs:WP_046676093	DNA topoisomerase I [Sphingobacterium sp. Ag1].	29.79	705	441	25	1	678	1	678	6e-72	258
rs:WP_025505736	DNA topoisomerase III [Vibrio parahaemolyticus].	29.25	612	394	12	2	581	3	607	6e-72	257
rs:WP_025556707	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	7e-72	257
rs:WP_010781442	DNA topoisomerase III [Enterococcus gilvus].	29.56	619	387	13	2	611	3	581	7e-72	258
rs:WP_041342545	DNA topoisomerase III [Marinobacter similis].	29.45	652	412	17	1	614	1	642	7e-72	259
rs:WP_025541060	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	7e-72	257
rs:WP_003108987	DNA topoisomerase III [Pseudomonas aeruginosa].	28.64	667	421	19	1	629	1	650	7e-72	258
rs:WP_006216705	DNA topoisomerase III [Achromobacter piechaudii].	28.93	726	430	22	3	675	5	697	7e-72	261
rs:WP_012375808	DNA topoisomerase III [Opitutus terrae].	28.88	741	435	27	3	681	4	714	7e-72	262
rs:WP_034684347	DNA topoisomerase III [Enterococcus phoeniculicola].	28.85	662	403	19	2	644	3	615	7e-72	258
rs:WP_025141104	DNA topoisomerase III [Achromobacter sp. DH1f].	28.79	726	431	22	3	675	5	697	7e-72	261
tr:A0A0B6S0Y1_BURGL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.46	723	438	22	3	680	27	722	7e-72	261
rs:WP_025570202	DNA topoisomerase III [Vibrio parahaemolyticus].	30.07	612	389	14	2	581	3	607	7e-72	257
rs:WP_023966311	DNA topoisomerase III [Paenibacillus sp. JCM 10914].	28.95	639	395	16	3	615	4	609	7e-72	258
rs:WP_002056427	DNA topoisomerase III [Bacillus cereus].	29.96	711	427	19	1	661	2	691	7e-72	258
tr:A0A069DGA2_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.15	662	396	18	3	626	4	630	7e-72	258
rs:WP_012260746	DNA topoisomerase III [Bacillus weihenstephanensis].	29.92	712	413	18	1	655	1	683	7e-72	258
rs:WP_000766752	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.18	709	428	18	1	661	1	690	7e-72	258
rs:WP_029815742	DNA topoisomerase III [Vibrio parahaemolyticus].	29.25	612	394	12	2	581	3	607	7e-72	257
rs:WP_021453258	DNA topoisomerase III [Vibrio parahaemolyticus].	29.25	612	394	12	2	581	3	607	7e-72	257
rs:WP_025552790	DNA topoisomerase III [Vibrio parahaemolyticus].	29.25	612	394	12	2	581	3	607	7e-72	257
rs:WP_028211930	DNA topoisomerase III [Burkholderia mimosarum].	29.55	714	433	21	3	673	5	691	7e-72	261
rs:WP_042985232	DNA topoisomerase III [Bacillus mycoides].	29.97	684	410	15	41	673	42	707	7e-72	259
rs:WP_041273944	hypothetical protein, partial [Desulfobacterium autotrophicum].	28.98	704	450	21	2	673	3	688	7e-72	258
rs:WP_004534801	DNA topoisomerase III [Burkholderia pseudomallei].	29.08	619	396	17	1	587	1	608	7e-72	258
rs:WP_017772360	DNA topoisomerase III [Burkholderia kururiensis].	29.60	723	437	23	3	680	5	700	7e-72	261
rs:WP_018436954	DNA topoisomerase III [Burkholderia sp. JPY251].	29.97	714	430	22	3	673	5	691	7e-72	261
rs:WP_008810305	MULTISPECIES: DNA topoisomerase III [Parasutterella].	29.71	727	416	27	3	673	5	692	7e-72	261
rs:WP_032472606	DNA topoisomerase III [Vibrio cholerae].	30.16	620	378	15	2	581	3	607	7e-72	257
rs:WP_031764334	DNA topoisomerase III [Pseudomonas aeruginosa].	28.64	667	421	19	1	629	1	650	7e-72	258
rs:WP_000766739	DNA topoisomerase III [Bacillus thuringiensis].	30.17	716	419	19	1	661	1	690	8e-72	258
rs:WP_028781076	DNA topoisomerase III [Shewanella sp. 38A_GOM-205m].	28.96	625	401	15	1	591	1	616	8e-72	258
tr:A0A0A8RP43_PSEAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.64	667	421	19	1	629	1	650	8e-72	257
rs:WP_025848350	DNA topoisomerase III [Brevibacillus agri].	30.86	661	396	20	3	627	5	640	8e-72	258
rs:WP_001991674	DNA topoisomerase III [Bacillus cereus].	30.23	708	429	18	1	661	1	690	8e-72	258
tr:A0A0C4YA37_9BURK	SubName: Full=Cupriavidus basilensis strain 4G11 chromosome secondary, complete sequence {ECO:0000313|EMBL:AJG22342.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AJG22342.1};	28.34	674	429	19	1	631	1	663	8e-72	260
rs:WP_025631592	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	8e-72	257
rs:WP_020367826	DNA topoisomerase III, partial [Staphylococcus epidermidis].	34.68	568	332	19	3	552	4	550	8e-72	254
rs:WP_025627208	DNA topoisomerase III [Vibrio parahaemolyticus].	29.25	612	394	12	2	581	3	607	8e-72	257
rs:WP_025521195	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	8e-72	257
rs:WP_025800019	DNA topoisomerase I [Prevotella saccharolytica].	28.88	734	436	25	1	677	1	705	8e-72	258
rs:WP_003116834	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	28.64	667	421	19	1	629	1	650	8e-72	257
rs:WP_002202402	DNA topoisomerase III [Bacillus cereus].	30.20	712	424	19	1	661	1	690	8e-72	258
rs:WP_025793072	DNA topoisomerase III [Vibrio parahaemolyticus].	29.25	612	394	12	2	581	3	607	8e-72	257
rs:WP_004318624	DNA topoisomerase I [Bacteroides ovatus].	29.35	627	411	12	68	676	2	614	8e-72	256
rs:WP_025508783	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	8e-72	257
rs:WP_006845464	DNA topoisomerase [Weissella koreensis].	30.03	726	445	21	3	675	4	719	8e-72	258
rs:WP_025532715	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	8e-72	257
rs:WP_009855757	DNA topoisomerase III [Rubrivivax benzoatilyticus].	29.02	734	442	24	3	675	5	720	8e-72	261
rs:WP_043003296	DNA topoisomerase III [Comamonas testosteroni].	29.45	730	425	24	3	666	5	710	8e-72	262
rs:WP_035482038	DNA topoisomerase III [Burkholderia phenoliruptrix].	30.22	718	423	24	3	673	5	691	8e-72	261
rs:WP_028362087	DNA topoisomerase III [Burkholderia sp. JPY366].	30.22	718	423	24	3	673	5	691	8e-72	261
rs:WP_000766757	DNA topoisomerase III [Bacillus cereus].	29.90	719	417	19	1	661	1	690	8e-72	258
rs:WP_029810451	DNA topoisomerase III [Vibrio parahaemolyticus].	29.25	612	394	12	2	581	3	607	8e-72	257
rs:WP_014760411	DNA topoisomerase III [Bifidobacterium bifidum].	27.72	754	447	22	1	682	1	728	8e-72	258
rs:WP_000766733	DNA topoisomerase III [Bacillus cereus].	29.80	708	432	18	1	661	1	690	8e-72	258
rs:WP_025553795	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	8e-72	257
rs:WP_011237506	DNA topoisomerase III [Aromatoleum aromaticum].	28.08	723	450	25	2	680	4	700	8e-72	261
rs:WP_035686649	DNA topoisomerase III [Avibacterium paragallinarum].	28.93	643	409	15	1	614	1	624	8e-72	257
rs:WP_044292940	DNA topoisomerase III [Pseudomonas amygdali].	28.29	661	426	16	1	629	1	645	8e-72	257
rs:WP_029440902	DNA topoisomerase III [Bacillus thuringiensis].	29.94	708	431	17	1	661	1	690	9e-72	258
rs:WP_007838676	DNA topoisomerase I [Bacteroides dorei].	27.96	701	459	18	1	676	1	680	9e-72	258
rs:WP_036857240	DNA topoisomerase I [Prevotella denticola].	30.22	718	414	23	4	673	5	683	9e-72	258
rs:WP_029833579	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	9e-72	257
rs:WP_006691865	topoisomerase III [Selenomonas infelix].	28.79	667	424	17	1	631	1	652	9e-72	259
rs:WP_047215475	DNA topoisomerase III [Pandoraea thiooxydans].	29.70	724	429	25	3	673	5	701	9e-72	261
rs:WP_008950433	DNA topoisomerase III [Alishewanella jeotgali].	29.44	642	389	17	1	597	1	623	9e-72	256
rs:WP_011219248	DNA topoisomerase III [Photobacterium profundum].	30.10	618	387	14	2	581	3	613	9e-72	256
rs:WP_019573873	DNA topoisomerase III [Curvibacter lanceolatus].	29.23	732	429	24	3	666	5	715	9e-72	262
rs:WP_021449869	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	9e-72	257
tr:D5W9E3_BURSC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.97	714	430	22	3	673	22	708	9e-72	261
rs:WP_047284460	DNA topoisomerase III [Bifidobacterium bifidum].	27.89	753	441	24	1	679	1	725	9e-72	258
rs:WP_031382112	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	9e-72	257
rs:WP_031943207	TraE DNA topoisomerase [uncultured bacterium].	29.71	717	441	20	1	671	1	700	9e-72	258
rs:WP_039204385	DNA topoisomerase III, partial [Burkholderia glumae].	29.46	723	438	22	3	680	5	700	9e-72	260
rs:WP_012840372	DNA topoisomerase III [Comamonas testosteroni].	29.45	730	425	24	3	666	5	710	9e-72	262
rs:WP_020367186	DNA topoisomerase III [Staphylococcus epidermidis].	30.14	740	431	25	3	681	4	718	9e-72	258
rs:WP_014194428	DNA topoisomerase [Burkholderia sp. YI23].	29.35	736	441	21	3	680	5	719	9e-72	261
rs:WP_025535135	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	9e-72	257
rs:WP_003813716	DNA topoisomerase III [Bifidobacterium bifidum].	27.83	751	444	22	1	679	1	725	9e-72	258
rs:WP_029796813	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	9e-72	256
rs:WP_046959122	DNA topoisomerase III [Bacillus cereus].	29.90	719	417	19	1	661	1	690	9e-72	258
rs:WP_043741058	DNA topoisomerase III [Thauera sp. SWB20].	27.63	666	424	17	1	629	1	645	9e-72	257
rs:WP_021822369	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	9e-72	257
tr:A0A068Z373_BIFBI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.02	753	440	24	1	679	1	725	9e-72	258
rs:WP_029615659	DNA topoisomerase III [Pseudomonas putida].	28.87	613	390	14	1	581	1	599	9e-72	256
rs:WP_003072146	DNA topoisomerase III [Comamonas testosteroni].	29.45	730	425	24	3	666	5	710	9e-72	262
rs:WP_025528100	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	29.25	612	394	12	2	581	3	607	9e-72	256
rs:WP_002188055	DNA topoisomerase III [Bacillus cereus].	29.94	678	418	14	41	673	42	707	1e-71	258
rs:WP_037350384	DNA topoisomerase, partial [Selenomonas sp. oral taxon 137].	27.56	675	425	20	1	630	1	656	1e-71	257
rs:WP_027213817	DNA topoisomerase III [Burkholderia sp. WSM2232].	30.08	718	424	24	3	673	5	691	1e-71	261
rs:WP_031816622	DNA topoisomerase III [Vibrio parahaemolyticus].	29.25	612	394	12	2	581	3	607	1e-71	256
rs:WP_034022471	DNA topoisomerase III [Pseudomonas aeruginosa].	28.64	667	421	19	1	629	1	650	1e-71	257
tr:D8P0T1_RALSL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.73	713	433	22	3	673	5	691	1e-71	261
rs:WP_017251542	DNA topoisomerase III [Brevibacillus brevis].	31.00	658	399	20	3	627	5	640	1e-71	258
rs:WP_010954821	DNA topoisomerase III [Pseudomonas putida].	28.71	613	391	13	1	581	1	599	1e-71	256
rs:WP_022249592	DNA topoisomerase III [Eubacterium sp. CAG:274].	29.20	661	428	18	2	636	3	649	1e-71	258
rs:WP_007180672	DNA topoisomerase III [Burkholderia sp. Ch1-1].	28.70	662	422	18	1	629	1	645	1e-71	257
rs:WP_015001367	DNA topoisomerase III [Burkholderia phenoliruptrix].	30.22	718	423	24	3	673	5	691	1e-71	261
rs:WP_032967783	DNA topoisomerase III [Bordetella holmesii].	29.85	727	422	25	3	675	5	697	1e-71	260
rs:WP_022963028	DNA topoisomerase III [Pseudomonas pelagia].	29.05	685	423	22	1	646	1	661	1e-71	257
rs:WP_031828274	DNA topoisomerase III [Vibrio parahaemolyticus].	29.36	613	392	13	2	581	3	607	1e-71	256
rs:WP_046947023	DNA topoisomerase III [Bacillus cereus].	30.18	709	428	18	1	661	1	690	1e-71	258
rs:WP_010929538	MULTISPECIES: DNA topoisomerase III [Bordetella].	29.46	723	430	24	3	675	5	697	1e-71	261
rs:WP_047270549	DNA topoisomerase III [Bifidobacterium bifidum].	27.70	751	445	22	1	679	1	725	1e-71	258
rs:WP_029290885	DNA topoisomerase III [Pseudomonas fluorescens].	27.42	671	432	17	1	636	1	651	1e-71	256
rs:WP_029846690	DNA topoisomerase III [Vibrio parahaemolyticus].	29.36	613	392	13	2	581	3	607	1e-71	256
rs:WP_025789721	DNA topoisomerase III [Vibrio parahaemolyticus].	29.36	613	392	13	2	581	3	607	1e-71	256
rs:WP_000766744	DNA topoisomerase III [Bacillus cereus].	30.23	708	429	18	1	661	1	690	1e-71	258
rs:WP_034050572	DNA topoisomerase III [Pseudomonas aeruginosa].	27.63	666	424	17	1	629	1	645	1e-71	257
rs:WP_000766746	DNA topoisomerase III [Bacillus cereus].	29.66	708	433	18	1	661	1	690	1e-71	258
rs:WP_010632324	DNA topoisomerase III [Sporolactobacillus vineae].	30.16	630	383	18	3	614	5	595	1e-71	258
rs:WP_004576972	DNA topoisomerase III [Pseudomonas putida].	28.87	613	390	14	1	581	1	599	1e-71	256
rs:WP_025809783	DNA topoisomerase III [Pseudomonas chlororaphis].	28.23	666	420	19	1	629	1	645	1e-71	257
rs:WP_032542359	DNA topoisomerase I [Bacteroides fragilis].	29.65	705	455	20	1	684	1	685	1e-71	258
rs:WP_035978137	DNA topoisomerase III, partial [Burkholderia glumae].	29.46	723	438	22	3	680	5	700	1e-71	260
rs:WP_025889512	DNA topoisomerase III [Shewanella haliotis].	29.12	625	400	14	1	591	1	616	1e-71	257
rs:WP_032972388	DNA topoisomerase III [Bordetella hinzii].	29.61	726	425	24	3	675	5	697	1e-71	260
tr:A0A0D5MB95_ENTFC	SubName: Full=Topoisomerase 1A {ECO:0000313|EMBL:AJY53540.1};	28.43	707	454	17	3	667	4	700	1e-71	258
rs:WP_025598065	DNA topoisomerase III [Burkholderia sp. WSM2230].	29.83	714	431	21	3	673	5	691	1e-71	261
rs:WP_035303104	hypothetical protein, partial [Clostridium sp. HGF2].	29.84	630	405	15	1	615	1	608	1e-71	256
rs:WP_021620679	DNA topoisomerase [Aneurinibacillus aneurinilyticus].	28.53	715	467	18	1	676	1	710	1e-71	258
rs:WP_024348418	DNA topoisomerase III [[Clostridium] methoxybenzovorans].	30.17	686	413	22	1	654	1	652	1e-71	258
rs:WP_047123684	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	1e-71	256
rs:WP_045604644	DNA topoisomerase III [Vibrio parahaemolyticus].	29.69	613	390	13	2	581	3	607	1e-71	256
rs:WP_038426447	DNA topoisomerase III [Bifidobacterium longum].	27.25	723	470	22	1	679	1	711	1e-71	258
rs:WP_034410032	DNA topoisomerase III, partial [Derxia gummosa].	28.57	735	427	24	3	675	5	703	1e-71	260
rs:WP_033452845	DNA topoisomerase III [Bordetella bronchiseptica].	29.46	723	430	24	3	675	5	697	1e-71	260
rs:WP_040535462	hypothetical protein, partial [Legionella drancourtii].	28.77	664	422	18	1	629	1	648	1e-71	256
rs:WP_029842486	DNA topoisomerase III [Vibrio parahaemolyticus].	29.74	612	391	14	2	581	3	607	1e-71	256
rs:WP_000766777	DNA topoisomerase III [Bacillus cereus].	29.96	701	427	16	1	655	1	683	1e-71	258
rs:WP_015040782	DNA topoisomerase iii [Bordetella parapertussis].	29.46	723	430	24	3	675	5	697	1e-71	260
rs:WP_005017120	DNA topoisomerase III [Bordetella holmesii].	29.85	727	422	25	3	675	5	697	1e-71	260
rs:WP_016114467	DNA topoisomerase III [Bacillus cereus].	29.90	709	417	18	1	655	2	684	1e-71	258
rs:WP_029808658	DNA topoisomerase III [Vibrio parahaemolyticus].	29.25	612	394	12	2	581	3	607	1e-71	256
rs:WP_005461760	DNA topoisomerase III [Vibrio parahaemolyticus].	29.36	613	392	13	2	581	3	607	1e-71	256
rs:WP_016132735	DNA topoisomerase III [Bacillus cereus].	29.99	707	415	18	3	655	5	685	1e-71	258
rs:WP_033456757	DNA topoisomerase III [Bordetella bronchiseptica].	29.46	723	430	24	3	675	5	697	1e-71	260
rs:WP_042967424	DNA topoisomerase III, partial [Burkholderia glumae].	29.46	723	438	22	3	680	5	700	1e-71	260
rs:WP_025289344	DNA topoisomerase III [Bibersteinia trehalosi].	29.61	618	389	17	1	584	1	606	1e-71	256
rs:WP_044322389	DNA topoisomerase III [Pseudomonas amygdali].	28.29	661	426	16	1	629	1	645	1e-71	257
rs:WP_027406931	DNA topoisomerase [Anaerovibrio sp. RM50].	29.75	679	411	20	1	631	1	661	1e-71	260
rs:WP_010861635	DNA topoisomerase III [Enterococcus faecium].	28.39	708	453	18	3	667	4	700	1e-71	258
rs:WP_032962115	DNA topoisomerase III [Bordetella hinzii].	29.61	726	425	24	3	675	5	697	1e-71	260
rs:WP_029861830	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	1e-71	256
rs:WP_003064768	DNA topoisomerase III [Comamonas testosteroni].	29.45	730	425	24	3	666	5	710	1e-71	261
rs:WP_002484399	DNA topoisomerase III [Staphylococcus epidermidis].	30.14	740	431	25	3	681	4	718	1e-71	258
rs:WP_032978941	DNA topoisomerase III [Bordetella hinzii].	29.61	726	425	24	3	675	5	697	1e-71	260
rs:WP_045450152	DNA topoisomerase III [Burkholderia sp. RPE67].	29.55	714	433	21	3	673	5	691	1e-71	260
rs:WP_042305031	DNA topoisomerase III [Burkholderia terrae].	29.71	727	431	23	3	680	5	700	1e-71	260
rs:WP_000766747	DNA topoisomerase III [Bacillus cereus].	29.00	700	435	17	1	655	1	683	1e-71	258
rs:WP_000766743	DNA topoisomerase III [Bacillus cereus].	29.94	708	431	17	1	661	1	690	1e-71	258
rs:WP_029577833	DNA topoisomerase III [Bordetella hinzii].	29.61	726	425	24	3	675	5	697	1e-71	260
rs:WP_032957599	DNA topoisomerase III [Bordetella hinzii].	29.61	726	425	24	3	675	5	697	1e-71	260
rs:WP_014291218	DNA topoisomerase III [Oceanimonas sp. GK1].	30.27	621	393	18	1	588	1	614	1e-71	256
rs:WP_046460388	DNA topoisomerase III [Comamonas testosteroni].	29.45	730	425	24	3	666	5	710	1e-71	261
rs:WP_025578174	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	1e-71	256
rs:WP_013740648	DNA topoisomerase III [Selenomonas sputigena].	28.22	659	427	15	5	632	8	651	1e-71	258
rs:WP_043223945	DNA topoisomerase III [Bordetella hinzii].	29.61	726	425	24	3	675	5	697	1e-71	260
rs:WP_025521521	DNA topoisomerase III [Vibrio parahaemolyticus].	29.36	613	392	13	2	581	3	607	1e-71	256
rs:WP_046482944	DNA topoisomerase III [Pseudomonas veronii].	28.02	646	410	16	1	611	1	626	1e-71	256
tr:C9LWM4_SELS3	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.22	659	427	15	5	632	9	652	1e-71	257
rs:WP_000766758	DNA topoisomerase III [Bacillus cereus].	29.76	719	418	19	1	661	1	690	1e-71	257
rs:WP_013586805	DNA topoisomerase III [Burkholderia sp. CCGE1001].	30.22	718	423	24	3	673	5	691	1e-71	260
rs:WP_043192735	DNA topoisomerase III, partial [Burkholderia glumae].	29.46	723	438	22	3	680	5	700	2e-71	260
rs:WP_013671538	DNA topoisomerase I [Prevotella denticola].	29.60	706	429	19	1	673	2	672	2e-71	257
rs:WP_036846849	MULTISPECIES: DNA topoisomerase I [Porphyromonas].	29.67	701	435	22	1	673	2	672	2e-71	257
rs:WP_032826676	DNA topoisomerase III [Bordetella holmesii].	29.85	727	422	25	3	675	5	697	2e-71	260
rs:WP_045102431	DNA topoisomerase III [Aliivibrio wodanis].	29.74	622	371	15	2	574	3	607	2e-71	256
rs:WP_012584241	DNA topoisomerase III [Thauera sp. MZ1T].	29.32	730	440	24	2	682	4	706	2e-71	260
rs:WP_033458597	DNA topoisomerase III [Bordetella bronchiseptica].	29.32	723	431	24	3	675	5	697	2e-71	260
rs:WP_008606329	DNA topoisomerase III [Alishewanella aestuarii].	29.13	642	391	17	1	597	1	623	2e-71	256
rs:WP_023098549	hypothetical protein [Pseudomonas aeruginosa].	28.49	667	422	19	1	629	1	650	2e-71	256
rs:WP_000766749	DNA topoisomerase III [Bacillus thuringiensis].	29.38	708	422	17	1	655	1	683	2e-71	257
rs:WP_033839942	DNA topoisomerase III [Bordetella bronchiseptica].	29.32	723	431	24	3	675	5	697	2e-71	260
rs:WP_024699733	DNA topoisomerase III [Vibrio parahaemolyticus].	29.25	612	394	12	2	581	3	607	2e-71	256
rs:WP_003815970	DNA topoisomerase III [Bordetella bronchiseptica].	29.46	723	430	24	3	675	5	697	2e-71	260
rs:WP_010709815	DNA topoisomerase III [Enterococcus faecalis].	29.06	726	449	20	3	675	4	716	2e-71	258
rs:WP_014755959	DNA topoisomerase III [Pseudomonas putida].	28.87	613	390	14	1	581	1	599	2e-71	256
tr:F0GKV0_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	29.13	714	436	21	3	673	5	691	2e-71	259
rs:WP_003188538	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	29.88	723	412	19	1	661	1	690	2e-71	257
rs:WP_031849232	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	612	395	12	2	581	3	607	2e-71	256
rs:WP_000766748	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	29.38	708	422	17	1	655	1	683	2e-71	257
rs:WP_033450699	DNA topoisomerase III [Bordetella bronchiseptica].	29.46	723	430	24	3	675	5	697	2e-71	260
rs:WP_033469647	DNA topoisomerase III [Bordetella bronchiseptica].	29.46	723	430	24	3	675	5	697	2e-71	260
rs:WP_013337716	DNA topoisomerase III [Burkholderia sp. CCGE1003].	29.83	714	431	21	3	673	5	691	2e-71	260
rs:WP_029887822	DNA topoisomerase III [Pseudomonas putida].	28.99	614	388	16	1	581	1	599	2e-71	256
rs:WP_015877326	DNA topoisomerase III [Burkholderia glumae].	29.46	723	438	22	3	680	5	700	2e-71	260
rs:WP_014423558	DNA topoisomerase 3 [Selenomonas ruminantium].	29.44	676	411	20	1	629	1	657	2e-71	259
rs:WP_016104534	DNA topoisomerase III [Bacillus cereus].	30.06	712	425	19	1	661	1	690	2e-71	257
rs:WP_009876577	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	28.97	642	408	16	1	611	1	625	2e-71	256
rs:WP_025627575	DNA topoisomerase III [Vibrio parahaemolyticus].	30.46	591	372	14	2	560	3	586	2e-71	256
rs:WP_027349624	DNA topoisomerase III [Halotalea alkalilenta].	29.35	620	383	16	1	581	1	604	2e-71	256
rs:WP_015914564	DNA topoisomerase III [Acidovorax ebreus].	29.05	723	437	24	3	666	5	710	2e-71	261
rs:WP_031578390	DNA topoisomerase [Ruminobacter sp. RM87].	30.45	660	393	22	1	615	1	639	2e-71	256
rs:WP_012051818	DNA topoisomerase III [Pseudomonas putida].	28.87	613	390	14	1	581	1	599	2e-71	256
rs:WP_046922005	DNA topoisomerase III [Lactobacillus ruminis].	30.03	676	393	18	2	648	3	627	2e-71	257
rs:WP_034121403	hypothetical protein, partial [Peptococcaceae bacterium BICA1-7].	32.08	611	356	19	3	581	7	590	2e-71	254
rs:WP_046935705	DNA topoisomerase [Xanthomonas euvesicatoria].	29.85	717	440	20	1	671	1	700	2e-71	258
rs:WP_002118313	DNA topoisomerase III [Bacillus cereus].	29.90	719	417	19	1	661	1	690	2e-71	257
rs:WP_028249919	DNA topoisomerase III [Variovorax sp. URHB0020].	29.16	751	437	26	3	680	4	732	2e-71	261
gp:AP006725_567	putative DNA topoisomerase [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]	30.69	554	359	9	53	587	8	555	2e-71	254
rs:WP_023603551	DNA topoisomerase III [Aliivibrio logei].	28.96	618	381	13	2	574	3	607	2e-71	256
rs:WP_019937515	DNA topoisomerase III [Bordetella sp. FB-8].	29.09	722	434	21	3	675	6	698	2e-71	260
rs:WP_035565951	DNA topoisomerase III [Halomonas sp. KO116].	29.09	636	411	14	1	612	1	620	2e-71	255
rs:WP_000766750	DNA topoisomerase III [Bacillus cereus].	29.16	703	443	16	1	661	1	690	2e-71	257
tr:A0A0D6FEB7_ALCXX	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:CKG66100.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CKG66100.1};	29.12	728	426	24	3	675	5	697	2e-71	260
rs:WP_034021230	DNA topoisomerase III [Pseudomonas aeruginosa].	28.42	665	420	19	1	629	1	645	2e-71	256
rs:WP_011282367	TraE-like protein [Haemophilus influenzae].	28.12	761	450	24	1	682	1	743	2e-71	258
rs:WP_002320596	DNA topoisomerase [Enterococcus faecium].	29.91	682	418	17	40	675	19	686	2e-71	256
rs:WP_014565111	DNA topoisomerase [Lactobacillus delbrueckii].	27.76	724	449	19	3	676	4	703	2e-71	257
rs:WP_038748593	DNA topoisomerase III [Burkholderia pseudomallei].	29.49	712	436	21	3	673	5	691	2e-71	260
rs:WP_036813091	DNA topoisomerase III [Photorhabdus luminescens].	27.47	750	448	21	1	678	1	726	2e-71	257
rs:WP_024025285	DNA topoisomerase III [Marinomonas profundimaris].	31.93	617	374	18	1	581	1	607	2e-71	256
rs:WP_033448977	DNA topoisomerase III [Bordetella bronchiseptica].	29.46	723	430	24	3	675	5	697	2e-71	260
rs:WP_000766735	DNA topoisomerase III [Bacillus cereus].	30.08	708	430	18	1	661	1	690	2e-71	257
rs:WP_042199330	DNA topoisomerase III, partial [Escherichia coli].	31.09	579	362	16	61	608	8	580	2e-71	254
rs:WP_032735465	DNA topoisomerase III [Bifidobacterium longum].	27.25	723	470	22	1	679	1	711	2e-71	257
rs:WP_005615023	DNA topoisomerase III [Actinobacillus pleuropneumoniae].	30.30	637	403	17	1	606	1	627	2e-71	255
rs:WP_023557382	DNA topoisomerase III [Brevibacillus panacihumi].	28.04	749	440	24	3	673	4	731	2e-71	258
tr:F7NGY8_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.64	646	412	18	1	615	1	628	2e-71	257
rs:WP_002937562	DNA topoisomerase III [Thauera sp. 27].	29.16	727	445	23	2	682	4	706	2e-71	259
rs:WP_038502539	DNA topoisomerase III [Achromobacter xylosoxidans].	29.12	728	426	24	3	675	5	697	2e-71	260
rs:WP_000766782	DNA topoisomerase III [Bacillus thuringiensis].	30.08	708	430	18	1	661	1	690	2e-71	257
rs:YP_028031	DNA topoisomerase III [Bacillus anthracis str. Sterne].	29.80	708	432	17	1	661	1	690	2e-71	257
tr:G3A3B1_9RALS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.59	713	434	22	3	673	5	691	2e-71	259
rs:WP_003251239	DNA topoisomerase III [Pseudomonas putida].	28.87	613	390	14	1	581	1	599	2e-71	256
rs:WP_039122908	DNA topoisomerase III [Lactobacillus ruminis].	29.99	677	392	20	2	648	3	627	2e-71	256
rs:WP_011803324	DNA topoisomerase III [Polaromonas naphthalenivorans].	29.62	746	436	28	3	680	4	728	2e-71	261
rs:WP_020925716	DNA topoisomerase III [Achromobacter xylosoxidans].	29.12	728	426	24	3	675	5	697	2e-71	260
rs:WP_009655052	DNA topoisomerase III [Selenomonas sp. FOBRC6].	27.45	703	434	22	1	653	1	677	2e-71	257
rs:WP_031642429	MULTISPECIES: hypothetical protein [Listeria].	29.35	719	444	23	3	677	4	702	2e-71	257
rs:WP_028590838	DNA topoisomerase III [Paenibacillus panacisoli].	28.79	646	384	20	3	615	4	606	2e-71	257
rs:WP_027799096	DNA topoisomerase III [Burkholderia dilworthii].	29.55	714	433	21	3	673	5	691	2e-71	260
rs:WP_014072880	DNA topoisomerase III [Lactobacillus ruminis].	29.88	676	394	18	2	648	3	627	2e-71	256
rs:WP_038201453	DNA topoisomerase III [Xenophilus azovorans].	28.44	668	424	17	1	630	1	652	2e-71	256
rs:WP_006162279	DNA topoisomerase III [Cupriavidus basilensis].	29.29	717	440	22	3	677	5	696	2e-71	260
rs:WP_002012275	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	29.90	719	417	19	1	661	1	690	2e-71	257
rs:WP_027785766	DNA topoisomerase III [Burkholderia cepacia].	29.42	724	437	24	3	680	5	700	2e-71	259
rs:WP_032568995	DNA topoisomerase I [Bacteroides fragilis].	29.66	735	436	25	3	684	6	712	2e-71	257
rs:WP_008253114	DNA topoisomerase III [Limnobacter sp. MED105].	29.09	667	424	19	1	631	1	654	2e-71	256
rs:WP_006389468	DNA topoisomerase III [Achromobacter xylosoxidans].	29.12	728	426	24	3	675	5	697	2e-71	260
rs:WP_021250390	DNA topoisomerase III [Thauera terpenica].	29.72	720	426	26	2	670	4	694	2e-71	259
tr:G2ZP25_9RALS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.59	713	434	22	3	673	5	691	2e-71	259
tr:A2VUF6_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.32	723	439	22	3	680	28	723	2e-71	260
rs:WP_043154374	DNA topoisomerase III [Pseudomonas aeruginosa].	28.48	660	425	18	1	629	1	644	2e-71	256
tr:W7WFD4_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.31	713	428	23	3	657	5	699	2e-71	258
rs:WP_015867941	DNA topoisomerase III [Variovorax paradoxus].	29.24	749	437	26	3	680	4	730	2e-71	261
rs:WP_018999978	DNA topoisomerase III [Megamonas rupellensis].	29.46	672	417	15	1	629	1	658	2e-71	258
rs:WP_042586599	DNA topoisomerase III [Burkholderia sp. MSHR3999].	29.27	714	435	21	3	673	5	691	3e-71	259
rs:WP_032088751	DNA topoisomerase III [Bacillus aquimaris].	31.38	650	397	20	3	627	5	630	3e-71	257
rs:WP_000766734	MULTISPECIES: DNA topoisomerase III [Bacillus].	30.08	708	430	18	1	661	1	690	3e-71	257
rs:WP_014190097	DNA topoisomerase III [Burkholderia sp. YI23].	29.55	714	433	21	3	673	5	691	3e-71	259
rs:WP_026031846	DNA topoisomerase III [Pseudomonas putida].	28.71	613	391	14	1	581	1	599	3e-71	255
rs:WP_038709762	DNA topoisomerase III [Burkholderia sp. lig30].	29.41	714	434	22	3	673	5	691	3e-71	259
rs:WP_036679138	DNA topoisomerase I [Pedobacter oryzae].	30.91	618	369	19	1	583	1	595	3e-71	254
rs:WP_016449409	DNA topoisomerase III [Delftia acidovorans].	28.98	728	434	24	3	666	5	713	3e-71	261
rs:WP_021820845	DNA topoisomerase III [Halomonas sp. BJGMM-B45].	28.31	604	396	14	1	581	1	590	3e-71	256
rs:WP_029309062	DNA topoisomerase [Cupriavidus metallidurans].	28.98	728	438	21	3	673	5	710	3e-71	259
rs:WP_018076215	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	27.48	666	425	17	1	629	1	645	3e-71	256
rs:WP_012329439	DNA topoisomerase III [Burkholderia cenocepacia].	29.32	723	439	22	3	680	5	700	3e-71	259
tr:E4LQP4_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.84	630	405	15	1	615	1	608	3e-71	256
rs:WP_033471215	DNA topoisomerase III [Bordetella bronchiseptica].	29.32	723	431	24	3	675	5	697	3e-71	259
rs:WP_045325423	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	3e-71	255
rs:WP_045625682	DNA topoisomerase III [Vibrio parahaemolyticus].	29.36	613	392	13	2	581	3	607	3e-71	255
rs:WP_025611875	DNA topoisomerase III [Vibrio parahaemolyticus].	28.92	612	396	12	2	581	3	607	3e-71	255
rs:WP_034368856	DNA topoisomerase III [Delftia sp. 670].	28.98	728	434	24	3	666	5	713	3e-71	260
rs:WP_028557675	DNA topoisomerase III [Paenibacillus sp. URHA0014].	30.50	659	385	21	3	627	4	623	3e-71	256
rs:WP_002148790	DNA topoisomerase III [Bacillus cereus].	30.06	712	425	19	1	661	1	690	3e-71	256
gp:HE577055_73	DNA topoisomerase III [Paenibacillus polymyxa M1]	32.52	575	332	15	40	574	41	599	3e-71	263
rs:WP_002200885	DNA topoisomerase III [Bacillus cereus].	30.06	712	425	19	1	661	1	690	3e-71	256
rs:WP_028699042	DNA topoisomerase III [Pseudomonas monteilii].	28.71	613	391	14	1	581	1	599	3e-71	255
rs:WP_028462024	DNA topoisomerase III [Nitrosomonas cryotolerans].	28.89	720	429	25	3	671	5	692	3e-71	259
rs:WP_040068217	DNA topoisomerase III [Aeromonas veronii].	28.13	718	466	14	2	680	5	711	3e-71	256
rs:WP_029857514	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	3e-71	255
rs:WP_009548295	DNA topoisomerase III [Burkholderiales bacterium JOSHI_001].	29.18	723	438	25	3	673	5	705	3e-71	259
rs:WP_003098974	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	28.49	667	422	19	1	629	1	650	3e-71	256
rs:WP_010929817	DNA topoisomerase III [Bordetella pertussis].	29.32	723	431	24	3	675	5	697	3e-71	259
rs:WP_016396426	DNA topoisomerase III family protein [Lactobacillus delbrueckii].	27.62	724	450	19	3	676	4	703	3e-71	256
rs:WP_019530976	hypothetical protein [Dasania marina].	30.19	616	387	16	1	581	1	608	3e-71	255
rs:WP_003818222	DNA topoisomerase iii [Bordetella bronchiseptica].	29.32	723	431	24	3	675	5	697	3e-71	259
rs:WP_042997783	DNA topoisomerase III [Bordetella bronchiseptica].	29.32	723	431	24	3	675	5	697	3e-71	259
rs:WP_014546643	DNA topoisomerase III [Fibrobacter succinogenes].	31.32	728	417	26	3	684	35	725	3e-71	259
rs:WP_042299241	DNA topoisomerase III [Burkholderia kururiensis].	29.41	714	434	22	3	673	5	691	3e-71	259
rs:WP_002158311	DNA topoisomerase III [Bacillus cereus].	30.06	712	425	19	1	661	1	690	3e-71	256
rs:WP_025526834	DNA topoisomerase III [Vibrio parahaemolyticus].	29.25	612	394	12	2	581	3	607	3e-71	255
rs:WP_008783291	DNA topoisomerase III [Bifidobacterium sp. 12_1_47BFAA].	27.11	723	471	22	1	679	1	711	3e-71	256
rs:WP_047218931	DNA topoisomerase III [Delftia lacustris].	28.98	728	434	24	3	666	5	713	3e-71	260
rs:WP_015042051	DNA topoisomerase iii [Bordetella bronchiseptica].	29.32	723	431	24	3	675	5	697	3e-71	259
rs:WP_009521553	DNA topoisomerase III [Ralstonia sp. PBA].	27.18	666	427	17	1	629	1	645	3e-71	256
rs:WP_035051234	DNA topoisomerase III [Carnobacterium pleistocenium].	29.99	707	445	21	1	673	1	691	3e-71	256
rs:WP_022444575	DNA topoisomerase [Sutterella sp. CAG:351].	29.01	717	445	22	2	675	4	699	3e-71	259
rs:WP_031856192	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	612	395	12	2	581	3	607	3e-71	255
rs:WP_017814627	DNA topoisomerase III [Paenibacillus sp. A9].	28.21	677	418	19	2	646	3	643	4e-71	256
rs:WP_034443475	hypothetical protein [Cloacibacillus evryensis].	30.01	683	410	25	1	640	1	658	4e-71	256
rs:WP_007057140	DNA topoisomerase III [Bifidobacterium longum].	26.82	727	468	21	1	679	1	711	4e-71	256
rs:WP_037990282	DNA topoisomerase III [Tepidiphilus margaritifer].	28.93	726	445	23	2	684	4	701	4e-71	258
rs:WP_008432102	DNA topoisomerase III [Planococcus donghaensis].	27.46	710	470	15	3	681	4	699	4e-71	256
rs:WP_025609941	DNA topoisomerase III [Vibrio parahaemolyticus].	29.74	612	391	14	2	581	3	607	4e-71	255
rs:WP_040128547	DNA topoisomerase III [Burkholderia cenocepacia].	29.18	723	440	22	3	680	5	700	4e-71	259
rs:WP_029827151	DNA topoisomerase III [Vibrio parahaemolyticus].	29.25	612	394	12	2	581	3	607	4e-71	255
rs:WP_047326379	DNA topoisomerase III [Delftia tsuruhatensis].	28.98	728	434	24	3	666	5	713	4e-71	260
rs:WP_027016978	DNA topoisomerase III [Comamonas composti].	28.49	744	456	22	3	687	5	731	4e-71	260
rs:WP_025219815	DNA topoisomerase III [Lysinibacillus varians].	30.26	704	448	21	4	675	6	698	4e-71	256
rs:WP_034000341	DNA topoisomerase III [Pseudomonas aeruginosa].	28.48	660	425	17	1	629	1	644	4e-71	255
rs:WP_025072617	DNA topoisomerase I [Prevotella timonensis].	29.90	699	429	21	4	673	5	671	4e-71	256
rs:WP_015432516	DNA topoisomerase III [Bibersteinia trehalosi].	29.74	622	383	18	1	584	1	606	4e-71	254
rs:WP_000766773	DNA topoisomerase III [Bacillus cereus].	29.80	708	432	18	1	661	1	690	4e-71	256
rs:WP_005819871	DNA topoisomerase I [Bacteroides fragilis].	29.50	705	456	20	1	684	1	685	4e-71	256
rs:WP_025500282	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	612	395	12	2	581	3	607	4e-71	255
rs:WP_041080612	DNA topoisomerase III [Bifidobacterium longum].	27.11	723	471	22	1	679	1	711	4e-71	256
rs:WP_009728377	DNA topoisomerase III [Selenomonas sp. F0473].	26.86	685	417	20	1	630	1	656	4e-71	256
rs:WP_002932995	DNA topoisomerase III [Thauera sp. 28].	29.30	727	444	23	2	682	4	706	4e-71	259
rs:WP_024813405	DNA topoisomerase III [Acidovorax sp. JHL-3].	29.20	726	434	23	3	666	5	712	4e-71	260
rs:WP_027414696	DNA topoisomerase III [Aneurinibacillus terranovensis].	29.37	681	395	23	3	646	4	635	4e-71	256
rs:WP_012550681	DNA topoisomerase III [Aliivibrio salmonicida].	28.96	618	381	13	2	574	3	607	4e-71	255
rs:WP_046447476	DNA topoisomerase III [Acinetobacter sp. N54.MGS-139].	29.40	721	426	26	3	673	5	692	4e-71	258
rs:WP_045036739	DNA topoisomerase III [Photobacterium iliopiscarium].	27.93	666	436	14	1	640	1	648	4e-71	256
rs:WP_025753452	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	28.71	613	391	14	1	581	1	599	4e-71	255
rs:WP_006942369	DNA topoisomerase [Megasphaera micronuciformis].	29.86	643	407	14	1	615	1	627	4e-71	256
rs:WP_041104383	DNA topoisomerase III [Pseudomonas stutzeri].	27.61	670	419	18	1	629	1	645	4e-71	255
rs:WP_029851232	DNA topoisomerase III [Vibrio parahaemolyticus].	29.74	612	391	14	2	581	3	607	4e-71	255
rs:WP_007054353	DNA topoisomerase III [Bifidobacterium longum].	26.97	723	472	22	1	679	1	711	4e-71	256
rs:WP_040477989	DNA topoisomerase III, partial [Halomonas smyrnensis].	28.81	611	385	16	1	581	1	591	4e-71	254
rs:WP_022527651	toprim domain protein [Bifidobacterium longum].	27.11	723	471	22	1	679	1	711	4e-71	256
rs:WP_047287793	DNA topoisomerase III [Bifidobacterium bifidum].	27.56	751	446	22	1	679	1	725	5e-71	256
rs:WP_014370137	DNA topoisomerase III [Paenibacillus mucilaginosus].	29.09	667	392	20	3	630	4	628	5e-71	256
rs:WP_004233245	DNA topoisomerase III [Lysinibacillus fusiformis].	29.42	707	450	20	4	673	6	700	5e-71	256
rs:WP_003817179	DNA topoisomerase III [Bifidobacterium bifidum].	27.89	753	441	24	1	679	1	725	5e-71	256
rs:WP_010090307	DNA topoisomerase III [Burkholderia ubonensis].	29.13	714	436	21	3	673	5	691	5e-71	259
rs:WP_015463225	MULTISPECIES: DNA topoisomerase III [Xanthomonas].	28.09	680	433	21	1	639	1	665	5e-71	255
rs:WP_006763069	DNA topoisomerase III [Burkholderia dolosa].	29.44	720	426	23	3	673	5	691	5e-71	259
tr:B7U5A8_BACIU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.57	700	432	24	3	679	4	672	5e-71	257
rs:WP_000766772	DNA topoisomerase III [Bacillus cereus].	29.66	708	433	17	1	661	1	690	5e-71	256
rs:WP_021013085	DNA topoisomerase 3 [Variovorax paradoxus].	29.51	749	435	26	3	680	5	731	5e-71	260
rs:WP_029793271	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	15	2	581	3	607	5e-71	254
rs:WP_020838689	DNA topoisomerase III [Vibrio parahaemolyticus].	29.25	612	394	12	2	581	3	607	5e-71	254
rs:WP_038612001	DNA topoisomerase III [Pseudomonas alkylphenolia].	27.84	686	435	19	1	646	1	666	5e-71	255
rs:WP_006227776	DNA topoisomerase III [Achromobacter piechaudii].	29.32	723	431	22	3	675	5	697	5e-71	259
rs:WP_033959578	DNA topoisomerase III [Pseudomonas aeruginosa].	27.48	666	425	17	1	629	1	645	5e-71	255
rs:WP_006286037	topoisomerase IA [Paenibacillus popilliae].	27.85	754	456	23	3	685	4	740	5e-71	256
rs:WP_042780750	DNA topoisomerase III [Vibrio parahaemolyticus].	29.20	613	393	13	2	581	3	607	5e-71	254
rs:WP_018574459	hypothetical protein [Oligella ureolytica].	29.69	731	431	26	3	681	5	704	5e-71	259
rs:WP_016185174	DNA topoisomerase III [Enterococcus sulfureus].	29.45	703	449	18	3	670	5	695	5e-71	256
rs:WP_025041234	DNA topoisomerase III [Nitrosospira briensis].	29.81	718	423	24	3	670	5	691	5e-71	258
rs:WP_039032788	DNA topoisomerase III [Shewanella sp. ECSMB14102].	28.96	625	401	14	1	591	1	616	5e-71	255
rs:WP_046298229	DNA topoisomerase III [Verrucomicrobia bacterium IMCC26134].	27.94	741	444	28	3	680	4	717	5e-71	259
rs:WP_044143582	hypothetical protein, partial [Succinimonas amylolytica].	30.90	589	361	16	1	557	1	575	5e-71	253
rs:WP_008790738	MULTISPECIES: DNA topoisomerase III [Coprobacillus].	29.55	660	398	18	3	627	5	632	5e-71	256
rs:WP_020585005	DNA topoisomerase III [Endozoicomonas elysicola].	28.82	621	391	14	1	581	1	610	6e-71	254
rs:WP_020979454	DNA topoisomerase III [Burkholderia cenocepacia].	28.77	723	443	23	3	680	5	700	6e-71	258
rs:WP_017225403	DNA topoisomerase III [Cupriavidus basilensis].	29.29	717	440	23	3	677	5	696	6e-71	259
rs:WP_002879284	DNA topoisomerase [Lactobacillus delbrueckii].	28.03	685	420	18	41	676	43	703	6e-71	256
tr:A0A0A3VX20_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.67	701	429	16	1	655	1	683	6e-71	256
rs:WP_032135135	DNA topoisomerase I [Alistipes sp. AL-1].	27.43	700	461	18	1	676	1	677	6e-71	256
rs:WP_013184415	DNA topoisomerase III [Xenorhabdus nematophila].	27.60	750	447	21	1	678	1	726	6e-71	256
rs:WP_029842060	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	612	395	12	2	581	3	607	6e-71	254
rs:WP_025587447	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	14	2	581	3	607	6e-71	254
rs:WP_015465256	DNA topoisomerase III [Psychromonas sp. CNPT3].	29.21	623	392	13	1	588	1	609	6e-71	254
rs:WP_022579834	DNA topoisomerase III [Pseudomonas aeruginosa].	28.79	660	423	16	1	629	1	644	6e-71	255
rs:WP_016446175	DNA topoisomerase III [Delftia acidovorans].	27.40	668	423	17	1	629	1	645	6e-71	255
rs:WP_026020317	DNA topoisomerase III [Pseudomonas putida].	28.71	613	391	14	1	581	1	599	6e-71	254
rs:WP_044734317	DNA topoisomerase III [Shewanella algae].	28.96	625	401	15	1	591	1	616	6e-71	255
rs:WP_020067280	DNA topoisomerase III [Burkholderia bryophila].	30.08	718	424	24	3	673	5	691	6e-71	259
rs:WP_029805727	DNA topoisomerase III [Vibrio parahaemolyticus].	29.74	612	391	14	2	581	3	607	6e-71	254
rs:WP_000766765	DNA topoisomerase III [Bacillus cereus].	29.74	696	448	16	1	661	1	690	6e-71	256
rs:WP_043105734	DNA topoisomerase III [Pseudomonas aeruginosa].	27.31	670	421	17	1	629	1	645	6e-71	255
rs:WP_010080729	DNA topoisomerase III [Bifidobacterium longum].	26.97	723	472	22	1	679	1	711	6e-71	256
rs:WP_000766766	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.08	708	430	18	1	661	1	690	6e-71	256
tr:B5JFY2_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.06	733	438	22	3	682	4	707	7e-71	258
rs:WP_025635400	DNA topoisomerase III [Vibrio parahaemolyticus].	29.25	612	394	12	2	581	3	607	7e-71	254
rs:WP_035359824	DNA topoisomerase III [Achromobacter insuavis].	29.12	728	426	24	3	675	5	697	7e-71	258
rs:WP_042327278	DNA topoisomerase III [Burkholderia ginsengisoli].	29.63	712	435	21	3	673	5	691	7e-71	258
rs:WP_034749282	DNA topoisomerase III [Janthinobacterium lividum].	29.70	724	440	24	3	680	5	705	7e-71	258
rs:WP_033170946	DNA topoisomerase [Selenomonas sp. ND2010].	29.04	675	413	18	1	629	1	655	7e-71	258
rs:WP_000766764	DNA topoisomerase III [Bacillus cereus].	30.08	708	430	18	1	661	1	690	7e-71	256
rs:WP_023912248	DNA topoisomerase III [Pseudomonas aeruginosa].	27.35	669	424	17	1	630	1	646	7e-71	254
rs:WP_006050553	DNA topoisomerase III [Burkholderia graminis].	29.69	714	432	21	3	673	5	691	7e-71	258
rs:WP_003618392	DNA topoisomerase [Lactobacillus delbrueckii].	28.00	725	446	20	3	676	4	703	7e-71	256
rs:WP_027776822	DNA topoisomerase III [Burkholderia caledonica].	29.94	718	425	24	3	673	5	691	7e-71	258
rs:WP_015807862	DNA topoisomerase III [Pedobacter heparinus].	29.55	616	388	16	1	589	1	597	7e-71	253
rs:WP_009148607	DNA topoisomerase III [Thiorhodovibrio sp. 970].	25.77	776	457	20	3	675	4	763	7e-71	259
rs:WP_011658238	DNA topoisomerase III [Burkholderia ambifaria].	29.28	724	438	26	3	680	5	700	7e-71	258
rs:WP_020207115	DNA topoisomerase III [Cupriavidus sp. WS].	28.48	660	425	19	1	629	1	644	7e-71	254
rs:WP_034030437	DNA topoisomerase III [Pseudomonas aeruginosa].	28.68	659	425	17	1	629	1	644	7e-71	254
rs:WP_040900160	DNA topoisomerase III, partial [Verrucomicrobiae bacterium DG1235].	29.06	733	438	22	3	682	5	708	7e-71	258
rs:WP_017170279	hypothetical protein, partial [Xanthomonas axonopodis].	27.84	607	393	18	70	639	1	599	7e-71	254
rs:WP_025809837	DNA topoisomerase III [Pseudomonas chlororaphis].	26.69	667	431	16	1	629	1	647	7e-71	254
rs:WP_012205960	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	28.48	660	425	17	1	629	1	644	8e-71	254
rs:WP_041956145	DNA topoisomerase III [Vibrio parahaemolyticus].	29.74	612	391	14	2	581	3	607	8e-71	254
rs:WP_027608787	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	28.71	613	391	14	1	581	1	599	8e-71	254
rs:WP_009353583	DNA topoisomerase, partial [Veillonella sp. oral taxon 780].	30.09	658	377	20	34	633	1	633	8e-71	255
rs:WP_044423294	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	28.11	644	415	15	1	614	1	626	8e-71	254
rs:WP_035020436	DNA topoisomerase III [Carnobacterium sp. WN1374].	29.80	698	454	16	3	673	5	693	8e-71	255
rs:WP_038152891	DNA topoisomerase [Veillonella montpellierensis].	31.88	596	362	16	1	557	1	591	8e-71	256
rs:WP_023098636	hypothetical protein [Pseudomonas aeruginosa].	28.91	685	427	19	1	646	1	664	8e-71	254
rs:WP_025622790	DNA topoisomerase III [Vibrio parahaemolyticus].	29.90	612	390	15	2	581	3	607	8e-71	254
rs:WP_028257636	DNA topoisomerase [Veillonella montpellierensis].	32.05	596	361	16	1	557	1	591	8e-71	256
rs:WP_034208701	DNA topoisomerase III [Burkholderia cepacia].	28.77	723	443	23	3	680	5	700	8e-71	258
rs:WP_039394586	DNA topoisomerase III [Pandoraea sputorum].	29.44	720	436	22	3	673	5	701	8e-71	258
rs:WP_025716118	DNA topoisomerase III, partial [Paenibacillus sp. 1-18].	30.23	612	372	20	3	577	4	597	8e-71	254
rs:WP_040056402	DNA topoisomerase III [Bacillus sp. REN51N].	28.83	673	395	17	3	646	4	621	8e-71	255
rs:WP_046683462	DNA topoisomerase III [Janthinobacterium sp. KBS0711].	29.70	724	440	24	3	680	5	705	8e-71	258
rs:WP_000766781	DNA topoisomerase III [Bacillus cereus].	29.80	708	432	17	1	661	1	690	8e-71	255
rs:WP_000766753	DNA topoisomerase III [Bacillus cereus].	29.24	708	423	17	1	655	1	683	8e-71	255
rs:WP_023519206	DNA topoisomerase III, partial [Enterococcus mundtii].	29.69	586	363	13	41	614	3	551	9e-71	254
rs:WP_005832597	DNA topoisomerase I [Bacteroides uniformis].	28.61	699	448	20	3	676	6	678	9e-71	255
rs:WP_028259688	DNA topoisomerase III [Variovorax sp. JGI 0001016-M12].	29.11	749	438	26	3	680	5	731	9e-71	259
rs:WP_042059062	DNA topoisomerase III [Acidomonas methanolica].	27.94	680	435	18	1	641	1	664	9e-71	254
rs:WP_011546488	DNA topoisomerase III [Burkholderia cenocepacia].	29.18	723	440	22	3	680	5	700	9e-71	258
rs:WP_029902380	DNA topoisomerase I [Prevotella sp. 10(H)].	28.55	718	443	21	1	677	1	689	9e-71	255
rs:WP_025682658	DNA topoisomerase III [Paenibacillus sp. 1-49].	28.65	726	422	26	3	650	4	711	9e-71	256
rs:WP_029807206	DNA topoisomerase III [Vibrio parahaemolyticus].	29.74	612	391	14	2	581	3	607	9e-71	254
rs:WP_028363905	DNA topoisomerase III [Burkholderia sp. UYPR1.413].	29.60	723	437	22	3	680	5	700	9e-71	258
rs:WP_014424541	topoisomerase III [Selenomonas ruminantium].	28.20	695	443	18	2	654	4	684	9e-71	256
rs:WP_016742873	DNA topoisomerase III [Brevibacillus brevis].	31.06	660	396	22	3	627	5	640	9e-71	256
rs:WP_029969429	DNA topoisomerase III [Burkholderia sp. URHA0054].	29.69	714	432	21	3	673	5	691	9e-71	258
rs:WP_032738539	DNA topoisomerase III [Bifidobacterium longum].	26.97	723	472	22	1	679	1	711	1e-70	255
tr:R1K8N3_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.49	668	414	17	3	629	4	655	1e-70	254
rs:WP_018709306	DNA topoisomerase I [Bacteroides barnesiae].	29.79	715	433	29	1	676	1	685	1e-70	255
rs:WP_000766767	DNA topoisomerase III [Bacillus thuringiensis].	29.37	715	426	17	1	661	1	690	1e-70	255
rs:WP_037048578	hypothetical protein, partial [Psychromonas sp. SP041].	30.99	655	398	19	1	621	1	635	1e-70	254
rs:WP_000766763	DNA topoisomerase III [Bacillus cereus].	29.94	708	431	18	1	661	1	690	1e-70	255
rs:WP_017763026	DNA topoisomerase III [Bacillus thuringiensis].	29.65	715	424	18	1	661	1	690	1e-70	255
rs:WP_024667013	DNA topoisomerase III [Pseudomonas syringae].	28.61	664	420	17	1	629	1	645	1e-70	254
rs:WP_007728127	DNA topoisomerase III [Brevibacillus sp. BC25].	31.11	659	397	21	3	627	5	640	1e-70	255
rs:WP_000766774	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	29.94	708	431	18	1	661	1	690	1e-70	255
rs:WP_045035773	DNA topoisomerase III [Photobacterium iliopiscarium].	30.33	610	384	16	3	581	4	603	1e-70	254
rs:WP_034688920	DNA topoisomerase III [Enterococcus mundtii].	29.19	620	382	16	41	644	3	581	1e-70	254
rs:WP_047152889	DNA topoisomerase III [Aneurinibacillus tyrosinisolvens].	29.60	669	410	20	3	646	4	636	1e-70	255
rs:WP_041616898	DNA topoisomerase III [Paenibacillus mucilaginosus].	29.09	667	392	20	3	630	4	628	1e-70	255
rs:WP_018671825	DNA topoisomerase III [Brevibacillus laterosporus].	28.33	720	462	18	1	676	1	710	1e-70	256
rs:WP_035004309	DNA topoisomerase III, partial [Betaproteobacteria bacterium MOLA814].	29.13	745	436	25	3	680	4	723	1e-70	258
rs:WP_011486439	DNA topoisomerase III [Burkholderia xenovorans].	29.94	718	425	24	3	673	5	691	1e-70	258
rs:WP_003294153	DNA topoisomerase III [Pseudomonas stutzeri].	27.03	666	428	17	1	629	1	645	1e-70	254
tr:C0QH35_DESAH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.98	704	450	21	2	673	3	688	1e-70	258
rs:WP_005650116	DNA topoisomerase I [Parabacteroides merdae].	29.71	717	431	28	1	676	1	685	1e-70	255
rs:WP_042815526	DNA topoisomerase III, partial [Xanthomonas citri].	27.71	646	417	17	1	611	1	631	1e-70	253
rs:WP_000766762	DNA topoisomerase III [Bacillus cereus].	29.94	708	431	18	1	661	1	690	1e-70	255
rs:WP_000766771	MULTISPECIES: DNA topoisomerase III [Bacillus].	29.94	708	431	18	1	661	1	690	1e-70	255
rs:WP_041122970	DNA topoisomerase III [Jeotgalibacillus alimentarius].	29.70	707	441	19	3	673	4	690	1e-70	255
rs:WP_004566591	dna topoisomerase ec=5.99.1.2 [Bordetella bronchiseptica].	28.73	637	413	15	1	611	1	622	1e-70	254
rs:WP_043157988	DNA topoisomerase III [Pseudomonas aeruginosa].	27.33	666	426	17	1	629	1	645	1e-70	254
rs:WP_011689341	ATP-dependent DNA helicase RecQ [Candidatus Solibacter usitatus].	29.81	624	380	15	4	581	11	622	1e-70	261
tr:A0A0A5KV71_BURCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.18	723	440	22	3	680	5	700	1e-70	258
rs:WP_007105160	DNA topoisomerase III [Glaciecola polaris].	29.82	617	380	14	1	578	1	603	1e-70	253
rs:WP_011633249	DNA topoisomerase III [Nitrosomonas eutropha].	27.97	665	423	22	1	629	1	645	1e-70	254
rs:WP_017022826	DNA topoisomerase III [Aliivibrio logei].	28.96	618	381	13	2	574	12	616	1e-70	254
tr:V5AJ64_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.13	745	436	25	3	680	4	723	1e-70	258
rs:WP_012492332	MULTISPECIES: DNA topoisomerase III [Burkholderia cepacia complex].	28.77	723	443	23	3	680	5	700	1e-70	258
tr:A0A059ZW14_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.54	679	428	18	3	640	4	659	1e-70	256
tr:U5N7W5_9BURK	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AGX87651.1};	29.28	741	432	25	3	666	9	734	1e-70	259
rs:WP_000766769	DNA topoisomerase III [Bacillus cereus].	29.94	708	431	18	1	661	1	690	1e-70	255
rs:WP_017258167	DNA topoisomerase III [Pedobacter arcticus].	30.06	622	389	18	1	593	1	605	1e-70	253
rs:WP_039931121	hypothetical protein, partial [Anaerococcus lactolyticus].	30.85	603	367	15	1	585	1	571	1e-70	251
rs:WP_031632015	DNA topoisomerase III [Pseudomonas aeruginosa].	27.18	666	427	17	1	629	1	645	1e-70	254
rs:WP_041193372	DNA topoisomerase III [Candidatus Symbiobacter mobilis].	29.28	741	432	25	3	666	4	729	1e-70	259
rs:WP_015297075	DNA topoisomerase III [Vibrio parahaemolyticus].	28.92	612	396	12	2	581	3	607	1e-70	253
rs:WP_034021440	DNA topoisomerase III [Pseudomonas aeruginosa].	27.33	666	426	17	1	629	1	645	1e-70	254
rs:WP_036927629	DNA topoisomerase I, partial [Prevotella timonensis].	29.86	690	402	21	4	650	5	655	1e-70	254
rs:WP_008538783	DNA topoisomerase III [Megamonas funiformis].	29.46	672	417	15	1	629	1	658	1e-70	256
rs:WP_016852000	DNA topoisomerase III [Pseudomonas aeruginosa].	27.25	668	424	17	1	629	1	645	1e-70	254
rs:WP_036845149	DNA topoisomerase III [Photorhabdus temperata].	27.47	750	448	21	1	678	1	726	1e-70	255
rs:WP_038327617	DNA topoisomerase III, partial [beta proteobacterium SCGC AAA027-K21].	28.69	725	442	24	3	680	5	701	1e-70	258
rs:WP_034058298	DNA topoisomerase III [Pseudomonas aeruginosa].	28.59	668	421	20	1	629	1	651	1e-70	254
rs:WP_043859178	DNA topoisomerase III, partial [Bacillus subtilis].	30.86	606	380	11	3	581	4	597	1e-70	253
rs:WP_041763180	DNA topoisomerase III [Burkholderia phymatum].	29.46	723	438	22	3	680	5	700	1e-70	258
rs:WP_000766784	DNA topoisomerase III [Bacillus cereus].	29.94	708	431	18	1	661	1	690	1e-70	255
rs:WP_046788273	DNA topoisomerase III [Pseudomonas putida].	28.27	612	395	13	1	581	1	599	1e-70	253
rs:WP_023101516	hypothetical protein [Pseudomonas aeruginosa].	27.18	666	427	17	1	629	1	645	1e-70	254
rs:WP_036865053	DNA topoisomerase I [Porphyromonas sp. COT-108 OH2963].	29.66	708	426	24	1	673	2	672	1e-70	254
tr:R2B9H1_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.49	668	414	17	3	629	4	655	1e-70	254
rs:WP_010736168	DNA topoisomerase III, partial [Enterococcus mundtii].	29.69	586	363	13	41	614	3	551	1e-70	253
rs:WP_029854479	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	612	395	12	2	581	3	607	1e-70	253
rs:WP_021975616	topoisomerase IA [Bifidobacterium longum CAG:69].	26.97	723	472	22	1	679	1	711	1e-70	255
rs:WP_036868643	DNA topoisomerase I [Porphyromonas canoris].	29.67	701	435	22	1	673	2	672	1e-70	254
rs:WP_029192188	DNA topoisomerase III [Paenibacillus harenae].	28.93	719	422	24	3	670	4	684	2e-70	255
rs:WP_029845242	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	612	395	12	2	581	3	607	2e-70	253
rs:WP_025516126	DNA topoisomerase III [Vibrio parahaemolyticus].	29.74	612	391	14	2	581	3	607	2e-70	253
tr:A0A070C158_BURCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.05	723	441	22	3	680	5	700	2e-70	257
rs:WP_029044368	DNA topoisomerase III [Cupriavidus sp. WS].	29.01	717	442	22	3	677	5	696	2e-70	258
rs:WP_027865830	DNA topoisomerase III [Massilia alkalitolerans].	29.10	725	437	23	3	679	5	700	2e-70	258
rs:WP_015016310	DNA topoisomerase III [Acidovorax sp. KKS102].	29.18	723	434	23	3	666	5	708	2e-70	258
rs:WP_005485385	DNA topoisomerase III [Vibrio parahaemolyticus].	29.20	613	393	13	2	581	3	607	2e-70	253
rs:WP_008712616	DNA topoisomerase III [Synergistes sp. 3_1_syn1].	30.01	683	410	25	1	640	1	658	2e-70	254
rs:WP_037592209	DNA topoisomerase, partial [Sporomusa ovata].	29.97	644	405	17	1	615	1	627	2e-70	253
rs:WP_040241313	DNA topoisomerase III, partial [Xanthomonas citri].	27.71	646	417	17	1	611	1	631	2e-70	253
rs:WP_033992584	DNA topoisomerase III [Pseudomonas aeruginosa].	28.49	667	422	19	1	629	1	650	2e-70	254
rs:WP_042969683	DNA topoisomerase III [Bacillus thuringiensis].	29.66	708	433	17	1	661	1	690	2e-70	254
tr:F8F5Y2_PAEMK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.09	667	392	20	3	630	31	655	2e-70	255
rs:WP_025558293	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	612	395	12	2	581	3	607	2e-70	253
rs:WP_023112340	MULTISPECIES: hypothetical protein [Pseudomonas].	28.68	659	425	17	1	629	1	644	2e-70	254
rs:WP_041090884	DNA topoisomerase III [Jeotgalibacillus soli Cunha et al. 2012].	30.34	679	437	16	3	652	4	675	2e-70	254
rs:WP_025535495	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	612	395	12	2	581	3	607	2e-70	253
rs:WP_024533180	DNA topoisomerase III [Pseudomonas syringae].	27.99	661	428	16	1	629	1	645	2e-70	254
rs:WP_039866065	DNA topoisomerase I, partial [Pedobacter sp. BAL39].	29.34	610	389	14	1	583	1	595	2e-70	252
rs:WP_022373687	DNA topoisomerase III [Sutterella sp. CAG:397].	30.25	628	380	17	1	578	1	620	2e-70	253
rs:WP_034190221	DNA topoisomerase III [Burkholderia cenocepacia].	29.05	723	441	22	3	680	5	700	2e-70	257
rs:WP_045545704	DNA topoisomerase III [Vibrio sp. S512-13].	29.08	612	395	12	2	581	3	607	2e-70	253
tr:A0A0E3BE52_COMTE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:KGG84401.1};	29.26	598	375	15	3	561	1	589	2e-70	255
rs:WP_034784739	DNA topoisomerase III [Janthinobacterium lividum].	29.70	724	440	24	3	680	5	705	2e-70	257
gpu:CP011503_1109	DNA topoisomerase III [Burkholderia pyrrocinia]	29.18	723	440	22	3	680	5	700	2e-70	257
rs:WP_033467544	DNA topoisomerase III [Bordetella bronchiseptica].	28.89	727	429	24	3	675	5	697	2e-70	257
rs:WP_041154757	DNA topoisomerase III [Vibrio mytili].	28.77	650	421	14	1	614	1	644	2e-70	255
rs:WP_034032947	DNA topoisomerase III [Pseudomonas aeruginosa].	28.83	659	424	17	1	629	1	644	2e-70	253
rs:WP_031851482	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	612	395	12	2	581	3	607	2e-70	253
rs:WP_042997240	DNA topoisomerase III, partial [Bordetella bronchiseptica].	28.83	659	424	17	1	629	1	644	2e-70	253
rs:WP_025636901	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	612	395	12	2	581	3	607	2e-70	253
rs:WP_023585247	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	612	395	12	2	581	3	607	2e-70	253
rs:WP_039790282	DNA topoisomerase III, partial [Herbaspirillum huttiense].	28.89	727	441	22	3	680	5	704	2e-70	257
rs:WP_026435498	DNA topoisomerase III [Acidovorax sp. JHL-9].	29.32	723	433	23	3	666	5	708	2e-70	258
rs:WP_031815415	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	612	395	12	2	581	3	607	2e-70	253
rs:WP_025623522	DNA topoisomerase III [Vibrio parahaemolyticus].	29.74	612	391	14	2	581	3	607	2e-70	253
tr:B2JJU0_BURP8	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.46	723	438	22	3	680	27	722	2e-70	257
rs:WP_004380945	DNA topoisomerase I [Prevotella oulorum].	29.90	699	431	21	4	673	5	673	2e-70	254
tr:T0JN21_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.97	644	405	17	1	615	1	627	2e-70	253
rs:WP_000766770	DNA topoisomerase III [Bacillus cereus].	29.66	708	433	17	1	661	1	690	2e-70	254
tr:W6UCE3_9SPHI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.81	624	389	16	1	588	1	611	2e-70	252
rs:WP_016077855	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	29.37	715	426	17	1	661	1	690	2e-70	254
rs:WP_037443261	DNA topoisomerase I [Sphingobacterium antarcticum].	30.19	616	384	17	1	589	1	597	2e-70	252
rs:WP_036649449	DNA topoisomerase III [Paenibacillus pini].	29.70	643	386	20	3	615	4	610	2e-70	254
rs:WP_025526041	DNA topoisomerase III [Vibrio parahaemolyticus].	29.74	612	391	14	2	581	3	607	2e-70	253
rs:WP_046850419	DNA topoisomerase III [Nitrosomonas communis].	28.95	722	432	24	2	673	4	694	2e-70	256
rs:WP_031635081	DNA topoisomerase III [Pseudomonas aeruginosa].	27.14	678	438	18	1	641	1	659	2e-70	253
rs:WP_016488133	DNA topoisomerase III [Pseudomonas putida].	28.38	613	393	14	1	581	1	599	2e-70	253
rs:WP_003397193	DNA topoisomerase III [Anoxybacillus flavithermus].	29.00	662	408	17	3	646	4	621	2e-70	254
rs:WP_006750079	DNA topoisomerase III [Burkholderia ambifaria].	29.01	724	440	25	3	680	5	700	2e-70	257
rs:WP_019653808	DNA topoisomerase III [Variovorax paradoxus].	29.50	739	424	24	3	666	5	721	2e-70	258
rs:WP_045538028	DNA topoisomerase III, partial [Comamonadaceae bacterium B1].	30.13	667	394	21	3	611	10	662	2e-70	257
rs:WP_012273226	DNA topoisomerase III [Pseudomonas putida].	28.62	615	389	17	1	581	1	599	2e-70	253
rs:WP_000766755	DNA topoisomerase III [Bacillus cereus].	29.94	708	431	18	1	661	1	690	2e-70	254
rs:WP_027966602	DNA topoisomerase III [Halomonas halocynthiae].	30.26	618	383	20	1	581	1	607	2e-70	252
rs:WP_000766731	DNA topoisomerase III [Bacillus cereus].	29.37	715	426	17	1	661	1	690	3e-70	254
tr:D4LWP6_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.55	690	438	21	3	664	5	667	3e-70	254
rs:WP_014159680	DNA topoisomerase III [Pseudoxanthomonas spadix].	28.61	664	419	19	1	629	1	644	3e-70	253
rs:WP_028632332	DNA topoisomerase III [Pseudomonas parafulva].	28.10	612	396	12	1	581	1	599	3e-70	253
rs:WP_000217286	DNA topoisomerase III [Bacillus cereus].	29.90	709	426	19	3	661	4	691	3e-70	254
rs:WP_007881181	DNA topoisomerase III [Herbaspirillum sp. CF444].	29.38	725	432	22	3	677	5	699	3e-70	257
rs:WP_021782144	MULTISPECIES: DNA topoisomerase III [Pseudomonas putida group].	28.55	613	392	14	1	581	1	599	3e-70	253
rs:WP_047073258	DNA topoisomerase III [Brevibacillus formosus].	30.65	659	400	21	3	627	5	640	3e-70	254
tr:A0A0D1IX46_BACIU	SubName: Full=Bacillus subtilis strain HM-66 contig8, whole genome shotgun sequence {ECO:0000313|EMBL:KIU04544.1};	30.86	606	380	11	3	581	4	597	3e-70	253
rs:WP_018988644	DNA topoisomerase III [Azoarcus toluclasticus].	28.18	660	428	17	1	629	1	645	3e-70	253
rs:WP_004362285	DNA topoisomerase III [Thauera phenylacetica].	27.12	671	423	16	1	630	1	646	3e-70	253
rs:WP_020841080	DNA topoisomerase III [Vibrio parahaemolyticus].	29.74	612	391	14	2	581	3	607	3e-70	253
rs:WP_016343946	DNA topoisomerase [Burkholderia sp. RPE64].	29.41	714	434	22	3	673	5	691	3e-70	257
rs:WP_017004793	DNA topoisomerase III [Enterovibrio norvegicus].	31.12	617	384	15	2	587	3	609	3e-70	253
rs:WP_002326769	DNA topoisomerase III, partial [Enterococcus faecium].	29.76	672	407	20	3	629	4	655	3e-70	253
rs:WP_025508845	DNA topoisomerase III [Vibrio parahaemolyticus].	29.58	612	392	14	2	581	3	607	3e-70	253
rs:WP_034389805	DNA topoisomerase III [Delftia acidovorans].	28.85	728	435	24	3	666	5	713	3e-70	258
rs:WP_039318048	DNA topoisomerase III [Burkholderia sp. A9].	28.63	723	444	23	3	680	5	700	3e-70	256
rs:WP_039011607	DNA topoisomerase III [Cupriavidus sp. IDO].	29.01	717	444	22	3	677	5	698	3e-70	257
rs:WP_015402308	DNA topoisomerase III [Desulfocapsa sulfexigens].	29.52	735	431	27	3	685	6	705	3e-70	256
rs:WP_015395978	DNA topoisomerase III [Candidatus Kinetoplastibacterium desouzaii].	30.31	739	416	28	2	680	4	703	3e-70	256
rs:WP_013141536	DNA topoisomerase III [Xenorhabdus nematophila].	27.47	750	448	21	1	678	1	726	3e-70	254
rs:WP_015512177	Topoisomerase IA [Bifidobacterium longum].	26.83	723	473	22	1	679	1	711	3e-70	254
rs:WP_027101633	DNA topoisomerase III [Comamonadaceae bacterium URHA0028].	29.02	734	430	25	3	666	6	718	3e-70	258
rs:WP_040142560	DNA topoisomerase III [Burkholderia cenocepacia].	28.71	714	439	22	3	673	5	691	3e-70	256
rs:WP_014235929	DNA topoisomerase III [Azospira oryzae].	28.61	727	443	24	2	676	4	706	3e-70	256
rs:WP_040107074	DNA topoisomerase [Azotobacter chroococcum].	29.30	727	430	22	1	671	1	699	3e-70	254
rs:WP_010628045	DNA topoisomerase III [Halomonas sp. KM-1].	28.43	605	395	14	1	581	1	591	3e-70	252
rs:WP_025732981	DNA topoisomerase III [Carnimonas nigrificans].	28.18	628	380	17	1	581	1	604	3e-70	253
rs:WP_041315236	hypothetical protein, partial [Heliobacterium modesticaldum].	26.16	734	463	18	3	676	4	718	3e-70	254
rs:WP_012365004	DNA topoisomerase III [Burkholderia ambifaria].	28.87	724	441	25	3	680	5	700	3e-70	256
tr:A0A060NXQ2_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.13	667	394	21	3	611	11	663	3e-70	257
rs:WP_046226190	DNA topoisomerase III [Paenibacillus dauci].	28.06	677	419	19	2	646	3	643	3e-70	254
tr:A0A099E931_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.41	616	389	14	1	581	1	599	3e-70	253
rs:WP_043332461	DNA topoisomerase III [Cobetia marina].	27.06	643	396	15	1	581	1	632	3e-70	254
rs:WP_016414676	DNA topoisomerase III [Halomonas anticariensis].	28.16	625	409	16	1	601	1	609	3e-70	252
rs:WP_028353834	DNA topoisomerase III [Bordetella petrii].	28.75	727	430	24	3	675	5	697	3e-70	256
rs:WP_011979365	DNA topoisomerase III [Janthinobacterium sp. Marseille].	29.68	721	442	23	3	680	5	703	3e-70	256
rs:WP_015846389	DNA topoisomerase III [Paenibacillus sp. JDR-2].	28.83	725	437	23	3	684	4	692	3e-70	254
rs:WP_016958405	DNA topoisomerase III [Enterovibrio norvegicus].	31.12	617	384	15	2	587	3	609	3e-70	252
rs:WP_046803989	DNA topoisomerase III [Achromobacter sp. LC458].	29.18	723	432	22	3	675	5	697	3e-70	256
rs:WP_025896327	topoisomerase I, partial [Lactobacillus delbrueckii].	27.91	688	417	19	41	676	43	703	3e-70	254
rs:WP_028229620	DNA topoisomerase [Burkholderia ferrariae].	27.77	731	446	23	3	676	5	710	3e-70	256
rs:WP_026781568	DNA topoisomerase III [Polaromonas sp. EUR3 1.2.1].	29.29	751	431	29	3	680	4	727	3e-70	258
rs:WP_012202816	DNA topoisomerase III [Delftia acidovorans].	28.85	728	435	24	3	666	5	713	4e-70	257
rs:WP_035815289	hypothetical protein, partial [Cupriavidus basilensis].	28.04	674	431	19	1	631	1	663	4e-70	253
rs:WP_011875776	DNA topoisomerase [Burkholderia vietnamiensis].	28.22	730	447	26	3	676	5	713	4e-70	256
rs:WP_015893196	DNA topoisomerase III [Brevibacillus brevis].	30.91	660	397	22	3	627	5	640	4e-70	254
rs:WP_043825380	DNA topoisomerase III [Delftia sp. RIT313].	28.85	728	435	24	3	666	5	713	4e-70	257
rs:WP_022495166	DNA topoisomerase [Ruminococcus sp. CAG:624].	30.14	720	433	26	1	682	1	688	4e-70	253
rs:WP_033472286	DNA topoisomerase III [Bordetella bronchiseptica].	28.53	659	426	16	1	629	1	644	4e-70	253
rs:WP_018871403	DNA topoisomerase III [Thioalkalivibrio sp. ALgr3].	28.08	609	402	13	2	588	3	597	4e-70	251
rs:WP_036625876	DNA topoisomerase III [Paenibacillus macerans].	28.74	668	415	18	3	646	4	634	4e-70	253
rs:WP_012247063	DNA topoisomerase III [Bordetella petrii].	28.75	727	430	23	3	675	5	697	4e-70	256
rs:WP_031399650	MULTISPECIES: DNA topoisomerase III [Burkholderia].	28.77	723	443	23	3	680	5	700	4e-70	256
tr:A6E8D3_9SPHI	SubName: Full=Putative transposon excision protein {ECO:0000313|EMBL:EDM38263.1};	29.34	610	389	14	1	583	1	595	4e-70	252
rs:WP_034032722	DNA topoisomerase III [Pseudomonas aeruginosa].	28.64	660	424	16	1	629	1	644	4e-70	253
rs:WP_046290345	DNA topoisomerase III [Pandoraea oxalativorans].	29.44	720	436	21	3	673	5	701	4e-70	256
rs:WP_017462946	DNA topoisomerase III [Dyella ginsengisoli].	26.88	666	429	17	1	629	1	645	4e-70	253
rs:WP_044584352	DNA topoisomerase III [Bacillus bombysepticus].	29.66	708	433	17	1	661	1	690	4e-70	253
rs:WP_026762718	DNA topoisomerase [Selenomonas artemidis].	27.22	698	443	21	1	653	1	678	4e-70	254
rs:WP_027889424	DNA topoisomerase [Megamonas hypermegale].	30.21	672	410	18	1	629	1	656	4e-70	255
tr:A0A0A6VJT5_BIFLN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KHD94841.1};	26.56	723	475	22	1	679	1	711	4e-70	254
tr:C3CTB0_BACTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.85	680	416	19	3	654	8	654	4e-70	255
rs:WP_011988435	DNA topoisomerase [Yersinia pseudotuberculosis].	29.84	667	420	17	2	630	6	662	4e-70	253
rs:WP_013804570	DNA topoisomerase III [Delftia sp. Cs1-4].	28.85	728	435	24	3	666	5	713	4e-70	257
rs:WP_000766756	DNA topoisomerase III [Bacillus cereus].	29.94	708	431	18	1	661	1	690	4e-70	253
rs:WP_036793769	DNA topoisomerase III [Photobacterium phosphoreum].	30.05	619	383	17	1	581	1	607	4e-70	252
rs:WP_007179718	DNA topoisomerase III [Burkholderia sp. Ch1-1].	29.81	718	426	24	3	673	5	691	4e-70	256
rs:WP_006844378	DNA topoisomerase I [Dysgonomonas mossii].	27.75	699	470	16	1	680	1	683	4e-70	253
rs:WP_005338472	hypothetical protein [Dorea formicigenerans].	28.63	688	440	20	3	664	5	667	4e-70	253
rs:WP_033496031	DNA topoisomerase III [Bifidobacterium biavatii].	27.35	735	463	18	1	679	1	720	4e-70	254
rs:WP_023124756	hypothetical protein [Pseudomonas aeruginosa].	28.64	660	424	16	1	629	1	644	5e-70	252
rs:WP_006829051	DNA topoisomerase III [Planococcus antarcticus].	27.71	711	467	17	3	681	4	699	5e-70	253
rs:WP_005494459	DNA topoisomerase III [Vibrio parahaemolyticus].	29.58	612	392	13	2	581	3	607	5e-70	252
tr:E4LK90_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.70	675	424	21	1	630	1	656	5e-70	258
rs:WP_006464583	DNA topoisomerase III [Herbaspirillum frisingense].	29.10	725	442	22	3	680	5	704	5e-70	256
rs:WP_024360979	DNA topoisomerase III [Lysinibacillus sphaericus].	30.11	704	449	21	4	675	6	698	5e-70	253
rs:WP_019392302	DNA topoisomerase III [Bacillus endophyticus].	28.68	673	396	17	3	646	4	621	5e-70	253
rs:WP_000090078	DNA topoisomerase III [Bacillus thuringiensis].	29.85	680	416	19	3	654	5	651	5e-70	254
rs:WP_032737758	DNA topoisomerase III [Bifidobacterium longum].	26.97	723	472	22	1	679	1	711	5e-70	253
rs:WP_009440429	DNA topoisomerase [Selenomonas sp. oral taxon 138].	27.63	684	412	23	1	630	1	655	5e-70	253
rs:WP_010345965	DNA topoisomerase III [Paenibacillus peoriae].	30.23	612	372	20	3	577	4	597	5e-70	254
rs:WP_033448876	MULTISPECIES: DNA topoisomerase III [Alcaligenaceae].	28.53	659	426	16	1	629	1	644	5e-70	252
rs:WP_034079732	DNA topoisomerase III [Pseudomonas aeruginosa].	28.79	660	423	16	1	629	1	644	5e-70	252
rs:WP_007566594	DNA topoisomerase I [Bacteroides coprocola].	29.59	713	437	25	1	676	1	685	5e-70	253
rs:WP_016174178	DNA topoisomerase III [Enterococcus saccharolyticus].	28.85	662	403	18	2	644	3	615	5e-70	253
rs:WP_017006904	DNA topoisomerase III [Enterovibrio norvegicus].	30.79	617	386	15	2	587	3	609	5e-70	252
rs:WP_006759746	DNA topoisomerase III [Burkholderia ambifaria].	29.01	724	440	25	3	680	5	700	5e-70	256
rs:WP_011051421	DNA topoisomerase III [Xanthomonas citri].	27.94	680	431	21	1	639	1	662	5e-70	252
rs:WP_022343863	DNA topoisomerase [Clostridium sp. CAG:356].	30.67	639	374	16	2	578	4	635	5e-70	252
rs:WP_040187403	DNA topoisomerase III [Halomonas salina].	26.92	650	429	15	1	622	1	632	5e-70	251
rs:WP_016082039	DNA topoisomerase III [Bacillus cereus].	29.37	715	426	18	1	661	1	690	5e-70	253
rs:WP_009350711	DNA topoisomerase [Selenomonas artemidis].	27.41	675	426	20	1	630	1	656	5e-70	253
rs:WP_018949090	DNA topoisomerase III [Thioalkalivibrio sp. ALMg11].	28.90	609	397	14	2	588	3	597	6e-70	251
rs:WP_028996896	DNA topoisomerase III [Azohydromonas australica].	29.88	676	377	24	3	611	5	650	6e-70	256
rs:WP_028693701	DNA topoisomerase III [Pseudomonas cremoricolorata].	27.66	611	400	13	1	581	1	599	6e-70	252
rs:WP_022227915	DNA topoisomerase [Megamonas funiformis CAG:377].	29.32	672	418	15	1	629	1	658	6e-70	254
rs:WP_000766754	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	29.94	708	431	18	1	661	1	690	6e-70	253
rs:WP_018885393	DNA topoisomerase III [Paenibacillus massiliensis].	28.37	645	388	19	3	615	4	606	6e-70	253
rs:WP_036835670	DNA topoisomerase III [Pontibacillus litoralis].	30.74	706	421	23	2	676	3	671	6e-70	252
rs:WP_047185807	DNA topoisomerase III, partial [Bacilli bacterium VT-13-104].	31.54	612	368	16	3	581	4	597	6e-70	251
rs:WP_006416665	DNA topoisomerase III [Burkholderia multivorans].	28.71	714	439	22	3	673	5	691	6e-70	256
rs:WP_006401840	DNA topoisomerase III [Burkholderia multivorans].	28.71	714	439	22	3	673	5	691	6e-70	256
rs:WP_017244814	DNA topoisomerase III [Pseudomonas stutzeri].	27.03	666	428	17	1	629	1	645	6e-70	252
rs:WP_047351249	DNA topoisomerase III, partial [Diaphorobacter sp. J5-51].	28.83	732	427	25	3	666	5	710	6e-70	256
tr:B0TFR0_HELMI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.16	734	463	18	3	676	4	718	6e-70	254
rs:WP_039407184	DNA topoisomerase III [Pandoraea pulmonicola].	28.37	726	436	21	3	673	5	701	6e-70	256
rs:WP_035015800	DNA topoisomerase III [Catenovulum agarivorans].	30.42	618	383	14	1	578	1	611	6e-70	252
rs:WP_006693315	hypothetical protein [Selenomonas infelix].	27.17	703	446	22	1	658	1	682	6e-70	253
rs:WP_023523820	DNA topoisomerase III [Enterococcus mundtii].	28.05	713	449	18	3	667	4	700	6e-70	253
rs:WP_041025084	DNA topoisomerase III [Pseudomonas aeruginosa].	28.25	662	426	17	1	630	1	645	6e-70	252
rs:WP_037353159	DNA topoisomerase III, partial [Salinivibrio socompensis].	28.97	611	392	14	2	581	3	602	6e-70	251
rs:WP_031356953	DNA topoisomerase III [Burkholderia sordidicola].	29.27	714	435	21	3	673	5	691	6e-70	256
rs:WP_028613339	DNA topoisomerase III [Pseudomonas putida].	28.43	612	394	13	1	581	1	599	6e-70	251
rs:WP_010464480	DNA topoisomerase III [Acidovorax radicis].	29.05	723	435	24	3	666	5	708	6e-70	256
rs:WP_045265866	DNA topoisomerase III [Comamonas aquatica].	28.79	733	426	24	3	666	5	710	7e-70	256
rs:WP_035184697	topoisomerase I [Lactobacillus delbrueckii].	28.51	670	436	18	41	676	43	703	7e-70	253
rs:WP_044847346	DNA topoisomerase III [Burkholderia sp. USM B20].	28.57	714	440	22	3	673	5	691	7e-70	255
rs:WP_008063202	DNA topoisomerase III [Methyloversatilis universalis].	27.80	723	453	20	2	678	4	703	7e-70	256
rs:WP_033955548	DNA topoisomerase III [Pseudomonas aeruginosa].	27.25	668	424	17	1	629	1	645	7e-70	252
rs:WP_035865596	DNA topoisomerase III [Cupriavidus sp. SK-3].	29.43	717	439	23	3	677	5	696	7e-70	256
rs:WP_017877597	DNA topoisomerase III [Janthinobacterium sp. CG3].	29.45	730	448	23	3	687	5	712	7e-70	256
rs:WP_041101310	DNA topoisomerase III, partial [Sulfuritalea hydrogenivorans].	28.07	716	447	22	2	673	3	694	7e-70	255
rs:WP_039576863	DNA topoisomerase III [Pseudomonas parafulva].	28.07	627	396	16	1	586	1	613	7e-70	252
rs:WP_005787064	DNA topoisomerase III [Pseudomonas synxantha].	28.16	664	430	14	1	633	1	648	7e-70	251
rs:WP_013973300	MULTISPECIES: DNA topoisomerase III [Pseudomonas putida group].	28.25	616	390	14	1	581	1	599	7e-70	251
rs:WP_010393247	DNA topoisomerase III [Janthinobacterium lividum].	29.83	724	439	25	3	680	5	705	7e-70	256
rs:WP_038674145	DNA topoisomerase [Pelosinus sp. UFO1].	29.99	667	408	20	1	629	1	646	7e-70	251
rs:WP_046710691	ATP-dependent DNA helicase RecQ [Myxococcus fulvus].	28.53	638	386	16	4	578	27	657	7e-70	260
rs:WP_015471954	Topoisomerase IA [Xanthomonas citri].	28.94	660	422	18	1	629	1	644	7e-70	252
rs:WP_033407435	DNA topoisomerase III, partial [Uliginosibacterium gangwonense].	28.55	718	445	24	2	676	4	696	7e-70	255
rs:WP_034179361	DNA topoisomerase III [Burkholderia pyrrocinia].	29.05	723	441	22	3	680	5	700	8e-70	255
tr:W1WUK7_9ZZZZ	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:ETJ21606.1}; Flags: Fragment;	33.86	573	339	17	60	615	15	564	8e-70	252
rs:WP_025818497	DNA topoisomerase III [Vibrio parahaemolyticus].	29.41	612	393	13	2	581	3	607	8e-70	251
rs:WP_046388544	DNA topoisomerase [Streptococcus uberis].	31.02	722	416	25	3	670	4	697	8e-70	253
rs:WP_033981900	DNA topoisomerase III [Pseudomonas aeruginosa].	28.25	662	426	17	1	630	1	645	8e-70	252
rs:WP_020361462	DNA topoisomerase III [Pseudomonas syringae].	29.24	643	407	17	1	613	1	625	8e-70	252
rs:WP_003283902	DNA topoisomerase III [Pseudomonas stutzeri].	27.27	616	397	13	1	581	1	600	8e-70	251
rs:WP_035038491	DNA topoisomerase III [Aquabacterium sp. NJ1].	28.95	753	442	27	3	680	5	739	8e-70	255
rs:WP_033986198	DNA topoisomerase III [Pseudomonas aeruginosa].	27.48	666	425	17	1	629	1	645	8e-70	252
rs:WP_044393820	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	28.31	664	422	17	1	629	1	645	8e-70	252
rs:WP_042415945	DNA topoisomerase III [Comamonas aquatica].	28.79	733	426	24	3	666	5	710	8e-70	256
rs:WP_038496368	DNA topoisomerase III [Janthinobacterium agaricidamnosum].	29.36	729	436	25	3	680	5	705	8e-70	255
rs:WP_033474391	DNA topoisomerase III [Bordetella bronchiseptica].	28.64	660	424	17	1	629	1	644	8e-70	252
rs:WP_035509775	DNA topoisomerase III [Burkholderia sp. MP-1].	29.13	714	436	22	3	673	5	691	8e-70	255
rs:WP_004612752	hypothetical protein [Tyzzerella nexilis].	28.26	690	440	20	3	664	5	667	8e-70	252
rs:WP_000366823	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	27.33	750	449	21	1	678	1	726	8e-70	253
rs:WP_047351293	DNA topoisomerase III [Diaphorobacter sp. J5-51].	28.48	660	425	18	1	629	1	644	9e-70	251
rs:WP_039370276	DNA topoisomerase III [Pandoraea pnomenusa].	29.64	722	432	23	3	673	5	701	9e-70	255
rs:WP_041556619	DNA topoisomerase III [Carnobacterium sp. 17-4].	29.81	701	450	18	3	673	5	693	9e-70	253
rs:WP_039099504	DNA topoisomerase III [Lactobacillus curvatus].	30.05	619	385	14	2	610	4	584	9e-70	252
rs:WP_021159862	DNA topoisomerase III [Burkholderia sp. AU4i].	28.91	723	442	22	3	680	5	700	9e-70	255
rs:WP_032570624	DNA topoisomerase I [Bacteroides fragilis].	28.91	709	436	26	1	676	1	674	9e-70	252
rs:WP_040244399	DNA topoisomerase III [Xanthomonas citri].	28.94	660	422	18	1	629	1	644	9e-70	251
rs:WP_035596778	DNA topoisomerase III [Halomonas salina].	28.31	611	388	15	1	581	1	591	9e-70	251
rs:WP_032542096	DNA topoisomerase III, partial [Peptoclostridium difficile].	28.25	669	430	18	31	670	4	651	9e-70	252
rs:WP_019751272	DNA topoisomerase III [Pseudomonas putida].	27.10	668	425	17	1	629	1	645	9e-70	251
rs:WP_047335925	DNA topoisomerase III [Pseudomonas fluorescens].	27.18	666	427	17	1	629	1	645	9e-70	251
rs:WP_035824548	DNA topoisomerase III [Janthinobacterium sp. RA13].	29.56	724	441	24	3	680	5	705	9e-70	255
rs:WP_043378607	DNA topoisomerase III [Comamonas aquatica].	28.79	733	426	24	3	666	5	710	1e-69	256
rs:WP_033840334	DNA topoisomerase III [Bordetella bronchiseptica].	28.79	660	423	17	1	629	1	644	1e-69	251
rs:WP_016253291	MULTISPECIES: hypothetical protein [Proteobacteria].	28.38	659	427	17	1	629	1	644	1e-69	251
rs:WP_021022293	DNA topoisomerase III [Salinivibrio costicola].	29.01	617	384	15	2	581	3	602	1e-69	251
rs:WP_029881403	MULTISPECIES: hypothetical protein [Paenibacillus].	28.29	700	446	16	26	687	11	692	1e-69	252
rs:WP_011869699	DNA topoisomerase III [Herminiimonas arsenicoxydans].	29.36	722	444	22	3	680	5	704	1e-69	255
rs:WP_045786180	DNA topoisomerase III [Ralstonia mannitolilytica].	27.33	666	426	17	1	629	1	645	1e-69	251
rs:WP_033955185	DNA topoisomerase III [Pseudomonas aeruginosa].	28.49	667	422	19	1	629	1	650	1e-69	251
tr:F4BPK6_CARS1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.81	701	450	18	3	673	9	697	1e-69	252
rs:WP_035275918	DNA topoisomerase III [Desulfobulbus japonicus].	28.33	720	446	20	3	679	5	697	1e-69	254
rs:WP_028022843	DNA topoisomerase III [Enterovibrio calviensis].	31.23	618	382	15	2	587	3	609	1e-69	251
rs:WP_007052706	DNA topoisomerase III [Bifidobacterium longum].	26.27	727	472	21	1	679	1	711	1e-69	252
tr:I3Z129_BELBD	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	32.76	583	352	16	1	559	1	567	1e-69	249
rs:WP_025513247	DNA topoisomerase III [Bordetella trematum].	27.64	662	429	16	1	629	1	645	1e-69	251
rs:WP_017249528	DNA topoisomerase III [Brevibacillus brevis].	27.21	746	448	23	3	673	4	729	1e-69	253
rs:WP_012419946	DNA topoisomerase III [Akkermansia muciniphila].	28.22	730	453	24	3	683	5	712	1e-69	255
tr:Q3II06_PSEHT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.09	585	371	18	31	581	10	590	1e-69	250
rs:WP_014386700	MULTISPECIES: DNA topoisomerase III [Vibrionaceae].	28.62	650	422	14	1	614	1	644	1e-69	253
rs:WP_045377142	hypothetical protein [Enterobacter aerogenes].	29.96	681	407	21	5	640	8	663	1e-69	251
rs:WP_037582686	DNA topoisomerase [Streptococcus anginosus].	34.07	546	305	15	61	587	14	523	1e-69	248
rs:WP_015254593	DNA topoisomerase III [Thermobacillus composti].	27.59	743	455	21	3	675	4	733	1e-69	253
rs:WP_016833774	DNA topoisomerase III [Herbaspirillum lusitanum].	29.05	723	443	22	3	680	5	702	1e-69	255
rs:WP_022372341	DNA topoisomerase [Sutterella sp. CAG:397].	29.15	717	440	23	3	676	4	695	1e-69	254
rs:WP_012584772	DNA topoisomerase III [Thauera sp. MZ1T].	26.88	666	429	17	1	629	1	645	1e-69	251
rs:WP_000186172	DNA topoisomerase III [Bacillus cereus].	27.98	722	457	17	4	679	6	710	1e-69	252
rs:WP_033991652	DNA topoisomerase III [Pseudomonas aeruginosa].	28.64	660	424	16	1	629	1	644	1e-69	251
rs:WP_046224208	DNA topoisomerase III [Vibrio sp. ECSMB14106].	28.62	650	422	14	1	614	1	644	1e-69	253
rs:WP_011267044	DNA topoisomerase III [Pseudomonas syringae].	28.31	664	422	17	1	629	1	645	1e-69	251
rs:WP_021348945	hypothetical protein [Elizabethkingia meningoseptica].	31.49	705	421	23	1	673	1	675	1e-69	251
rs:WP_036874401	DNA topoisomerase I, partial [Prevotella nigrescens].	29.96	671	422	22	36	677	3	654	1e-69	251
rs:WP_022020959	DNA topoisomerase [Bacteroides sp. CAG:661].	29.57	717	432	28	1	676	1	685	1e-69	252
rs:WP_024763865	DNA topoisomerase III [Pseudomonas nitroreducens].	28.55	662	425	17	1	629	1	647	1e-69	251
tr:V8CKV1_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.96	671	422	22	36	677	2	653	1e-69	251
rs:WP_046482630	DNA topoisomerase III [Pseudomonas veronii].	28.18	660	427	16	1	629	1	644	1e-69	251
rs:WP_011807073	DNA topoisomerase III [Acidovorax sp. JS42].	28.83	732	427	25	3	666	5	710	1e-69	256
rs:WP_036210415	DNA topoisomerase III [Massilia sp. LC238].	29.05	723	440	22	3	679	5	700	1e-69	255
rs:WP_022197248	DNA topoisomerase III [Akkermansia muciniphila CAG:154].	28.22	730	453	24	3	683	5	712	1e-69	254
rs:WP_004178242	DNA topoisomerase III [Nitrosospira sp. APG3].	29.65	715	430	23	3	671	5	692	1e-69	254
rs:WP_044955363	DNA topoisomerase III, partial [Lachnospiraceae bacterium 1_4_56FAA].	32.44	487	297	11	1	471	1	471	1e-69	246
rs:WP_027788846	DNA topoisomerase III [Burkholderia cepacia].	28.63	723	444	23	3	680	5	700	1e-69	254
rs:WP_047149922	DNA topoisomerase III [Pseudomonas sp. TJI-51].	28.25	616	390	14	1	581	1	599	1e-69	251
rs:WP_029499016	DNA topoisomerase III [Kurthia huakuii].	28.39	701	465	15	3	673	4	697	1e-69	252
rs:WP_036247736	DNA topoisomerase III [Massilia sp. BSC265].	31.19	654	379	22	3	610	5	633	1e-69	255
rs:WP_023004588	DNA topoisomerase III [Halomonas sp. PBN3].	27.39	606	400	12	1	581	1	591	1e-69	250
rs:WP_027313023	DNA topoisomerase III [Balneatrix alpica].	28.78	608	382	10	1	578	1	587	1e-69	250
rs:WP_038654227	DNA topoisomerase I [Mucinivorans hirudinis].	29.71	700	439	25	1	676	1	671	1e-69	251
rs:WP_009754085	DNA topoisomerase TopB [Selenomonas sp. oral taxon 149].	26.83	671	433	17	1	630	1	654	1e-69	252
rs:WP_041779466	DNA topoisomerase I, partial [Belliella baltica].	33.04	578	347	16	1	554	1	562	1e-69	249
rs:WP_016134173	DNA topoisomerase III [Bacillus cereus].	29.62	709	432	18	1	661	1	690	1e-69	252
rs:WP_009558242	DNA topoisomerase [Lactobacillus equicursoris].	30.07	715	442	21	3	676	4	701	1e-69	252
rs:WP_012289980	DNA topoisomerase III [Finegoldia magna].	30.74	719	411	25	1	687	1	664	2e-69	251
rs:WP_039613170	DNA topoisomerase III [Pseudomonas sp. C5pp].	28.06	613	395	13	1	581	1	599	2e-69	250
rs:WP_013236594	DNA topoisomerase III [Herbaspirillum seropedicae].	28.75	727	442	22	3	680	5	704	2e-69	255
rs:WP_011899410	DNA topoisomerase III [Aeromonas salmonicida].	27.55	686	438	15	1	640	1	673	2e-69	252
rs:WP_009657658	DNA topoisomerase III [Selenomonas sp. FOBRC9].	27.00	674	430	19	1	630	1	656	2e-69	252
rs:WP_007430622	DNA topoisomerase III [Paenibacillus sp. Aloe-11].	30.23	612	372	20	3	577	4	597	2e-69	253
rs:WP_015270975	DNA topoisomerase III [Pseudomonas putida].	28.34	614	392	14	1	581	1	599	2e-69	251
rs:WP_043221507	DNA topoisomerase III [Pseudomonas balearica].	27.10	668	425	17	1	629	1	645	2e-69	251
rs:WP_009902112	DNA topoisomerase III [Burkholderia thailandensis].	29.21	712	438	21	3	673	5	691	2e-69	254
rs:WP_033990595	DNA topoisomerase III [Pseudomonas aeruginosa].	28.64	660	424	16	1	629	1	644	2e-69	251
rs:WP_031848119	DNA topoisomerase III [Vibrio parahaemolyticus].	29.58	612	392	13	2	581	3	607	2e-69	251
rs:WP_015617751	topoisomerase IA [Clostridium pasteurianum].	29.76	719	441	21	2	675	3	702	2e-69	252
tr:W0S9R8_9RHOO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.07	716	447	22	2	673	3	694	2e-69	254
rs:WP_044453283	DNA topoisomerase III [Pandoraea vervacti].	29.17	720	438	22	3	673	5	701	2e-69	254
tr:A0A061NZC6_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.63	709	449	19	3	673	12	701	2e-69	252
rs:WP_045241973	DNA topoisomerase III [Burkholderiaceae bacterium 16].	29.43	717	439	23	3	677	5	696	2e-69	254
rs:WP_046544168	DNA topoisomerase III [Burkholderia contaminans].	28.91	723	442	22	3	680	5	700	2e-69	254
rs:WP_032584277	DNA topoisomerase I [Bacteroides fragilis].	28.77	709	437	25	1	676	1	674	2e-69	251
rs:WP_027919719	DNA topoisomerase III [Pseudomonas sp. URMO17WK12:I8].	28.22	613	394	13	1	581	1	599	2e-69	250
rs:WP_011805445	DNA topoisomerase III [Acidovorax sp. JS42].	27.10	668	425	17	1	629	1	645	2e-69	251
rs:WP_028561132	DNA topoisomerase III [Paenibacillus pinihumi].	29.32	706	435	21	3	662	4	691	2e-69	253
tr:Q2T2B5_BURTA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.21	712	438	21	3	673	27	713	2e-69	254
rs:WP_019915921	DNA topoisomerase III [Methyloversatilis sp. FAM1].	28.69	725	442	23	2	676	4	703	2e-69	254
rs:WP_040241684	DNA topoisomerase III [Chromohalobacter japonicus].	28.26	605	396	15	1	581	1	591	2e-69	250
rs:WP_038787866	DNA topoisomerase III [Burkholderia pseudomallei].	29.21	712	438	21	3	673	5	691	2e-69	254
rs:WP_014215559	DNA topoisomerase III [Pediococcus claussenii].	30.36	662	393	22	2	644	4	616	2e-69	251
rs:WP_024671564	DNA topoisomerase III [Pseudomonas syringae].	28.14	661	427	16	1	629	1	645	2e-69	251
rs:WP_029613131	DNA topoisomerase III [Pseudomonas sp. ICMP 17674].	28.14	629	395	17	1	586	1	615	2e-69	251
rs:WP_014870525	DNA topoisomerase III [Marinobacter sp. BSs20148].	28.75	647	421	13	1	615	1	639	2e-69	252
rs:WP_007754045	DNA topoisomerase I [Bacteroides finegoldii].	28.27	672	435	21	28	673	13	663	2e-69	251
rs:WP_009908309	DNA topoisomerase III [Burkholderia thailandensis].	29.21	712	438	21	3	673	5	691	2e-69	254
rs:WP_000366819	DNA topoisomerase III [Vibrio mimicus].	27.33	750	449	21	1	678	1	726	2e-69	252
rs:WP_008265951	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	28.64	660	424	16	1	629	1	644	2e-69	251
rs:WP_021661971	DNA topoisomerase [Porphyromonas gingivalis].	29.48	709	453	21	1	684	1	687	2e-69	251
rs:WP_029133587	DNA topoisomerase III [Sedimenticola selenatireducens].	27.48	666	425	18	1	629	1	645	2e-69	251
rs:WP_010100721	DNA topoisomerase III [Burkholderia oklahomensis].	29.35	712	437	21	3	673	5	691	2e-69	254
rs:WP_032684902	DNA topoisomerase III [Bifidobacterium longum].	26.69	723	474	22	1	679	1	711	2e-69	251
rs:WP_043350930	DNA topoisomerase III [Cupriavidus basilensis].	29.29	717	440	23	3	677	5	696	2e-69	254
rs:WP_010845928	DNA topoisomerase [Xenorhabdus nematophila].	27.20	750	450	21	1	678	1	726	2e-69	252
rs:WP_005841157	DNA topoisomerase III [Mitsuokella multacida].	27.73	678	422	17	1	630	1	658	2e-69	253
rs:WP_022978745	DNA topoisomerase III [Ideonella sp. B508-1].	28.24	740	450	24	3	680	5	725	2e-69	254
rs:WP_043902450	DNA topoisomerase, partial [Enterococcus faecium].	29.84	667	403	20	3	624	4	650	2e-69	250
rs:WP_023106356	hypothetical protein [Pseudomonas aeruginosa].	28.77	643	410	16	1	611	1	627	2e-69	251
rs:WP_011804749	DNA topoisomerase III [Acidovorax sp. JS42].	28.53	659	426	17	1	629	1	644	2e-69	251
rs:WP_034017561	DNA topoisomerase III [Pseudomonas aeruginosa].	28.48	660	425	16	1	629	1	644	2e-69	251
rs:WP_010113203	DNA topoisomerase III [Burkholderia oklahomensis].	29.35	712	437	21	3	673	5	691	2e-69	254
rs:WP_023108431	hypothetical protein [Pseudomonas aeruginosa].	28.55	662	425	17	1	629	1	647	2e-69	251
rs:WP_011804699	DNA topoisomerase III [Acidovorax sp. JS42].	28.53	659	426	17	1	629	1	644	2e-69	251
rs:WP_046434613	DNA topoisomerase III [Akkermansia sp. UNK.MGS-1].	28.22	730	453	24	3	683	5	712	2e-69	254
rs:WP_027959218	MULTISPECIES: DNA topoisomerase III [Halomonas].	29.51	627	376	19	1	581	1	607	2e-69	249
rs:WP_044593054	DNA topoisomerase III, partial [Salmonella enterica].	28.69	617	392	15	1	581	1	605	2e-69	249
rs:WP_009893647	DNA topoisomerase III [Burkholderia thailandensis].	29.21	712	438	21	3	673	5	691	2e-69	254
rs:WP_025480863	DNA topoisomerase [Enterococcus faecium].	27.97	708	456	17	3	667	4	700	2e-69	252
rs:WP_028562548	DNA topoisomerase III [Paenibacillus pinihumi].	28.95	677	408	21	3	646	4	640	2e-69	251
rs:WP_032732402	DNA topoisomerase III, partial [Bacillus subtilis].	30.69	606	381	11	3	581	4	597	2e-69	249
rs:WP_024430099	DNA topoisomerase III [Burkholderia pseudomallei].	29.21	712	438	21	3	673	5	691	2e-69	254
tr:A0A088SE88_SALCE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AIO10315.2};	27.33	750	449	21	1	678	1	726	3e-69	251
rs:WP_017450116	MULTISPECIES: DNA topoisomerase III [Herbaspirillum].	28.75	727	442	22	3	680	5	704	3e-69	254
rs:WP_010805658	DNA topoisomerase III [Pandoraea sp. SD6-2].	29.42	724	431	25	3	673	5	701	3e-69	254
rs:WP_041409827	DNA topoisomerase III [Shewanella amazonensis].	28.08	641	396	17	1	590	1	627	3e-69	250
rs:WP_020616882	DNA topoisomerase III [Paenibacillus daejeonensis].	28.53	694	418	20	3	657	4	658	3e-69	251
rs:WP_034201218	DNA topoisomerase III [Burkholderia cepacia].	28.63	723	444	23	3	680	5	700	3e-69	254
rs:WP_039353751	DNA topoisomerase III [Mumia flava].	28.91	723	442	22	3	680	5	700	3e-69	254
tr:A0A097NA41_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.35	723	440	21	3	673	5	701	3e-69	254
rs:WP_016392731	DNA topoisomerase III [Pseudomonas plecoglossicida].	27.78	612	398	13	1	581	1	599	3e-69	250
rs:WP_036235380	DNA topoisomerase III [Massilia sp. JS1662].	29.10	725	437	25	3	679	5	700	3e-69	254
rs:WP_026477045	DNA topoisomerase III [Alkaliphilus transvaalensis].	31.27	646	359	19	3	580	5	633	3e-69	250
rs:WP_035554140	DNA topoisomerase III [Burkholderia sp. 9120].	29.35	712	437	21	3	673	5	691	3e-69	254
rs:WP_023872752	MULTISPECIES: DNA topoisomerase III [Pandoraea].	28.35	723	440	21	3	673	5	701	3e-69	254
rs:WP_011347592	DNA topoisomerase III [Xanthomonas euvesicatoria].	28.38	659	427	17	1	629	1	644	3e-69	250
rs:WP_038793625	DNA topoisomerase III [Burkholderia pseudomallei].	29.21	712	438	21	3	673	5	691	3e-69	254
rs:WP_038773172	DNA topoisomerase III [Burkholderia pseudomallei].	29.21	712	438	21	3	673	5	691	3e-69	254
rs:WP_013741022	DNA topoisomerase III [Selenomonas sputigena].	28.25	676	422	21	1	630	1	659	3e-69	252
tr:A1S7J4_SHEAM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.08	641	396	17	1	590	25	651	3e-69	251
rs:WP_034255044	DNA topoisomerase III [Bifidobacterium kashiwanohense].	26.62	725	468	21	1	677	1	709	3e-69	251
rs:WP_035933687	DNA topoisomerase III [Burkholderia glathei].	29.13	714	436	21	3	673	5	691	3e-69	254
rs:WP_044311780	DNA topoisomerase III [Pseudomonas syringae].	28.31	664	422	17	1	629	1	645	3e-69	250
rs:WP_033962290	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	28.55	662	425	17	1	629	1	647	3e-69	250
rs:WP_020342662	DNA topoisomerase III [Pseudomonas syringae].	28.31	664	422	17	1	629	1	645	3e-69	250
rs:WP_003425069	DNA topoisomerase III [Pseudomonas syringae].	28.31	664	422	17	1	629	1	645	3e-69	250
rs:WP_038784157	DNA topoisomerase III [Burkholderia pseudomallei].	29.21	712	438	21	3	673	5	691	3e-69	254
rs:WP_046060633	DNA topoisomerase III [Acidovorax citrulli].	28.51	726	438	25	3	666	5	711	3e-69	255
rs:WP_011831764	DNA topoisomerase [Methylibium petroleiphilum].	28.87	717	445	20	3	676	5	699	3e-69	253
rs:WP_038220216	DNA topoisomerase III [Xenorhabdus nematophila].	27.20	750	450	21	1	678	1	726	3e-69	251
rs:WP_043299896	DNA topoisomerase III [Burkholderia sp. TSV202].	29.21	712	438	21	3	673	5	691	3e-69	254
rs:WP_004523103	DNA topoisomerase III [Burkholderia pseudomallei].	29.21	712	438	21	3	673	5	691	3e-69	254
rs:WP_045244502	DNA topoisomerase III [Paenibacillus polymyxa].	29.90	612	374	20	3	577	4	597	3e-69	252
rs:WP_025677653	DNA topoisomerase III [Paenibacillus massiliensis].	31.48	613	365	22	3	577	4	599	3e-69	252
rs:WP_038409959	MULTISPECIES: DNA topoisomerase III [Pseudomonas putida group].	28.06	613	395	13	1	581	1	599	3e-69	249
rs:WP_018884314	DNA topoisomerase III [Paenibacillus massiliensis].	31.48	613	365	22	3	577	4	599	3e-69	252
rs:WP_023598157	DNA topoisomerase III [Pandoraea pnomenusa].	28.35	723	440	21	3	673	5	701	3e-69	254
rs:WP_039810558	DNA topoisomerase III [Jeotgalibacillus sp. D5].	30.70	710	430	22	3	673	4	690	3e-69	251
rs:WP_033699921	DNA topoisomerase III [Pseudomonas sp. WCS358].	28.25	616	390	14	1	581	1	599	3e-69	250
tr:F7JS33_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	32.44	487	297	11	1	471	1	471	3e-69	246
rs:WP_026334985	DNA topoisomerase III [Oxalobacteraceae bacterium AB_14].	29.08	729	438	25	3	680	5	705	3e-69	254
rs:WP_038758558	DNA topoisomerase III [Burkholderia pseudomallei].	29.21	712	438	21	3	673	5	691	3e-69	254
rs:WP_018395842	hypothetical protein [Bacillus sp. 37MA].	30.00	650	417	13	3	623	5	645	3e-69	251
rs:WP_011886436	MULTISPECIES: DNA topoisomerase III [Burkholderia].	28.77	723	443	23	3	680	5	700	3e-69	253
rs:WP_042827100	DNA topoisomerase III [Xanthomonas axonopodis].	28.25	662	424	18	1	629	1	644	3e-69	250
rs:WP_038781805	DNA topoisomerase III [Burkholderia pseudomallei].	29.21	712	438	21	3	673	5	691	3e-69	253
rs:WP_047242158	DNA topoisomerase III [Enterococcus cecorum].	29.75	632	371	19	2	611	3	583	3e-69	251
rs:WP_013391789	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	28.51	663	424	17	1	629	1	647	3e-69	250
rs:WP_033922359	topoisomerase I [Enterococcus faecalis].	28.75	727	455	19	3	679	5	718	3e-69	251
rs:WP_035208559	DNA topoisomerase III, partial [Acidovorax avenae].	28.51	726	438	25	3	666	5	711	3e-69	254
rs:WP_038704916	DNA topoisomerase III [Planococcus sp. PAMC 21323].	27.18	710	472	15	3	681	4	699	3e-69	251
rs:WP_008459746	DNA topoisomerase [Lactobacillus equicursoris].	29.72	710	451	20	3	676	4	701	3e-69	251
rs:WP_043275216	DNA topoisomerase III [Burkholderia pseudomallei].	29.21	712	438	21	3	673	5	691	3e-69	253
rs:WP_019689274	DNA topoisomerase III [Pseudomonas fluorescens].	28.28	647	407	16	1	611	1	626	3e-69	250
rs:WP_041753934	DNA topoisomerase III [Burkholderia rhizoxinica].	28.71	728	449	22	3	687	5	705	3e-69	254
rs:WP_023912627	DNA topoisomerase III [Pseudomonas aeruginosa].	27.92	659	430	17	1	629	1	644	3e-69	250
rs:WP_008513449	DNA topoisomerase III [Mucilaginibacter paludis].	29.73	619	383	17	1	589	1	597	3e-69	249
rs:WP_022451462	DNA topoisomerase [Clostridium sp. CAG:269].	30.73	654	367	19	1	578	1	644	3e-69	249
rs:WP_011489283	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	27.88	660	429	18	1	629	1	644	4e-69	250
rs:WP_027907079	DNA topoisomerase III [Pseudomonas taiwanensis].	28.16	618	388	15	1	581	1	599	4e-69	249
rs:WP_047340951	DNA topoisomerase III [Enterococcus cecorum].	29.14	628	380	16	2	611	3	583	4e-69	250
rs:WP_025339781	DNA topoisomerase III [Pseudomonas sp. FGI182].	28.50	614	391	15	1	581	1	599	4e-69	249
rs:WP_013519532	DNA topoisomerase III [Alicycliphilus denitrificans].	27.16	670	422	17	1	629	1	645	4e-69	250
rs:WP_024305832	topoisomerase I [Lactobacillus rhamnosus].	29.14	724	449	22	3	676	4	713	4e-69	251
rs:WP_038146532	DNA topoisomerase III [Verrucomicrobia bacterium SCGC AAA027-I19].	30.36	662	393	22	3	611	5	651	4e-69	253
rs:WP_034298270	DNA topoisomerase III [Herbaspirillum sp. RV1423].	28.87	724	437	21	3	677	5	699	4e-69	253
rs:WP_026432170	DNA topoisomerase III [Acidovorax oryzae].	28.40	729	435	25	3	666	5	711	4e-69	254
rs:WP_014485593	DNA topoisomerase III [Bifidobacterium longum].	26.69	727	469	21	1	679	1	711	4e-69	251
rs:WP_023381104	DNA topoisomerase III [Pseudomonas sp. VLB120].	28.16	618	388	15	1	581	1	599	4e-69	249
rs:WP_018964968	DNA topoisomerase I [Porphyromonas gulae].	29.76	709	425	25	1	673	1	672	4e-69	250
rs:WP_042113879	DNA topoisomerase III [Pandoraea apista].	29.42	724	431	24	3	673	5	701	4e-69	254
rs:WP_004228801	DNA topoisomerase III [Lysinibacillus fusiformis].	29.12	704	455	20	4	675	6	697	4e-69	251
rs:WP_047338624	DNA topoisomerase III [Enterococcus cecorum].	29.91	632	370	19	2	611	3	583	4e-69	250
rs:WP_016462896	DNA topoisomerase III [Bifidobacterium breve].	26.48	725	469	21	1	677	1	709	4e-69	251
rs:WP_045394961	DNA topoisomerase III [Vibrio rotiferianus].	29.20	661	411	20	1	624	1	641	4e-69	250
rs:WP_034339994	DNA topoisomerase III [Herbaspirillum sp. B39].	28.75	727	442	22	3	680	5	704	4e-69	253
rs:WP_031863365	DNA topoisomerase III, partial [Staphylococcus aureus].	32.75	571	340	15	65	615	18	564	4e-69	250
rs:WP_008333592	DNA topoisomerase III [Herbaspirillum sp. GW103].	28.61	727	443	22	3	680	5	704	4e-69	253
rs:WP_013596902	DNA topoisomerase III [Acidovorax avenae].	28.51	726	438	25	3	666	5	711	4e-69	254
tr:G4M7R3_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.13	714	436	21	3	673	5	691	4e-69	253
rs:WP_032438011	DNA topoisomerase III [Klebsiella pneumoniae].	27.20	750	450	21	1	678	1	726	4e-69	251
rs:WP_029527029	DNA topoisomerase III [Polaromonas glacialis].	28.61	748	444	27	3	680	4	731	4e-69	254
rs:WP_011353576	DNA topoisomerase III [Burkholderia lata].	28.91	723	442	22	3	680	5	700	4e-69	253
rs:WP_044314042	DNA topoisomerase III [Pseudomonas stutzeri].	28.64	660	424	16	1	629	1	644	4e-69	250
rs:WP_014895687	DNA topoisomerase III [Burkholderia cepacia].	28.91	723	442	22	3	680	5	700	4e-69	253
tr:B3DUF7_METI4	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.53	609	366	17	3	574	5	599	4e-69	253
rs:WP_020655828	DNA topoisomerase III [Massilia niastensis].	29.14	724	438	24	3	679	5	700	4e-69	253
tr:B1HHD0_BURPE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.21	712	438	21	3	673	42	728	4e-69	254
tr:A4T0M8_POLSQ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.10	725	433	22	3	673	7	704	4e-69	253
rs:WP_011485578	DNA topoisomerase III [Polaromonas sp. JS666].	28.89	751	434	28	3	680	4	727	4e-69	254
rs:WP_020162915	DNA topoisomerase III [Methyloversatilis universalis].	27.80	723	451	20	2	676	4	703	4e-69	253
rs:WP_028672238	DNA topoisomerase III [Saccharospirillum impatiens].	30.74	631	368	17	1	581	1	612	4e-69	249
rs:WP_032593111	DNA topoisomerase I [Bacteroides fragilis].	28.77	709	437	25	1	676	1	674	4e-69	250
rs:WP_025491675	DNA topoisomerase III, partial [Clostridiales bacterium VE202-27].	28.61	664	424	19	37	671	1	643	5e-69	249
rs:WP_003050384	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	28.16	664	426	17	1	629	1	648	5e-69	250
tr:E5AND1_BURRH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.71	728	449	22	3	687	26	726	5e-69	254
rs:WP_025341761	DNA topoisomerase III [Bifidobacterium breve].	26.48	725	469	21	1	677	1	709	5e-69	251
rs:WP_043184744	DNA topoisomerase III [Burkholderia cepacia].	28.77	723	443	23	3	680	5	700	5e-69	253
rs:WP_023082340	hypothetical protein [Pseudomonas aeruginosa].	28.29	661	425	18	1	629	1	644	5e-69	249
rs:WP_011797628	DNA topoisomerase III [Acidovorax citrulli].	28.40	729	435	25	3	666	5	711	5e-69	254
rs:WP_041655760	DNA topoisomerase III [Azoarcus sp. KH32C].	28.29	721	446	23	2	676	4	699	5e-69	253
rs:WP_016567477	DNA topoisomerase III [Pseudomonas syringae].	28.16	664	423	17	1	629	1	645	5e-69	249
tr:F9ZNS5_ACICS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.43	678	430	16	3	640	4	659	5e-69	251
rs:WP_010105941	DNA topoisomerase III [Verminephrobacter aporrectodeae].	29.70	660	398	19	3	611	5	649	5e-69	254
rs:WP_042484801	DNA topoisomerase III [Alcaligenes faecalis].	28.67	722	437	21	3	675	5	697	5e-69	253
rs:WP_005797214	DNA topoisomerase III [Acidovorax delafieldii].	28.79	726	433	24	3	666	5	708	5e-69	254
rs:WP_018211376	DNA topoisomerase III [Desulfitobacterium hafniense].	26.89	766	452	22	3	676	5	754	5e-69	251
rs:WP_000214250	hypothetical protein [Streptococcus agalactiae].	30.75	722	418	25	3	670	4	697	5e-69	250
rs:WP_034031049	DNA topoisomerase III [Pseudomonas aeruginosa].	26.88	666	429	17	1	629	1	645	5e-69	249
rs:WP_045336885	hypothetical protein [Enterobacter asburiae].	30.19	646	391	18	5	612	8	631	5e-69	250
rs:WP_003699035	DNA topoisomerase [Lactobacillus salivarius].	29.16	727	441	22	3	676	4	709	5e-69	251
rs:WP_009645530	DNA topoisomerase III [Selenomonas sp. CM52].	28.95	677	421	23	1	635	1	659	5e-69	251
rs:WP_033482602	DNA topoisomerase III [Xanthomonas axonopodis].	28.25	662	424	18	1	629	1	644	5e-69	249
rs:WP_004255068	DNA topoisomerase III [Thauera sp. 63].	27.18	666	427	17	1	629	1	645	5e-69	249
rs:WP_041982297	DNA topoisomerase III [Xenorhabdus nematophila].	27.20	750	450	21	1	678	1	726	6e-69	251
rs:WP_008092883	DNA topoisomerase III, partial [Pseudomonas sp. GM84].	28.25	616	390	15	1	581	1	599	6e-69	249
rs:WP_042957003	DNA topoisomerase [Enterococcus faecium].	27.63	713	452	18	3	667	4	700	6e-69	251
rs:WP_018715759	DNA topoisomerase III [Brachymonas chironomi].	28.21	663	427	17	1	629	1	648	6e-69	249
rs:WP_023443922	DNA topoisomerase III [Pseudomonas chloritidismutans].	27.03	666	428	17	1	629	1	645	6e-69	249
rs:WP_003821061	MULTISPECIES: dna topoisomerase ec=5.99.1.2 [Proteobacteria].	28.68	659	425	17	1	629	1	644	6e-69	249
rs:WP_003158613	DNA topoisomerase III [Pseudomonas aeruginosa].	28.31	664	425	17	1	629	1	648	6e-69	249
rs:WP_011460046	DNA topoisomerase III [Desulfitobacterium hafniense].	26.82	768	450	23	3	676	5	754	6e-69	251
rs:WP_037043705	DNA topoisomerase III [Pseudomonas sp. BAY1663].	27.80	615	395	13	1	581	1	600	6e-69	249
rs:WP_008352195	MULTISPECIES: DNA topoisomerase III [Burkholderia].	29.13	714	436	21	3	673	5	691	6e-69	253
rs:WP_021684478	DNA topoisomerase [Selenomonas sp. oral taxon 892].	27.08	698	444	21	1	653	1	678	6e-69	250
rs:WP_046720009	DNA topoisomerase III [Pseudomonas syringae].	28.16	664	423	17	1	629	1	645	6e-69	249
rs:WP_008445093	DNA topoisomerase 3 [Janthinobacterium sp. HH01].	28.81	729	440	25	3	680	5	705	6e-69	253
rs:WP_012438475	DNA topoisomerase III [Xanthomonas campestris].	28.25	662	424	18	1	629	1	644	6e-69	249
rs:WP_029996170	DNA topoisomerase III [Xanthomonas axonopodis].	28.25	662	424	18	1	629	1	644	6e-69	249
rs:WP_005596770	DNA topoisomerase III [Vibrio scophthalmi].	28.81	649	410	17	1	617	1	629	6e-69	249
rs:WP_003141052	DNA topoisomerase III [Pseudomonas aeruginosa].	26.73	666	430	16	1	629	1	645	6e-69	249
rs:WP_006024093	DNA topoisomerase III [Burkholderia thailandensis].	28.93	712	440	21	3	673	5	691	6e-69	253
rs:WP_018227575	DNA topoisomerase III [Methyloversatilis universalis].	27.94	723	452	20	2	678	4	703	6e-69	253
rs:WP_038762203	DNA topoisomerase III [Burkholderia pseudomallei].	29.21	712	438	21	3	673	5	691	6e-69	253
rs:WP_024890123	DNA topoisomerase III [Luteimonas huabeiensis].	28.07	659	429	17	1	629	1	644	6e-69	249
rs:WP_024004637	DNA topoisomerase III [Advenella kashmirensis].	30.46	732	422	29	3	680	5	703	6e-69	253
rs:WP_003435765	DNA topoisomerase III [Pseudomonas syringae].	27.95	662	427	17	1	629	1	645	7e-69	249
rs:WP_046075295	DNA topoisomerase III [Salinivibrio sp. KP-1].	29.82	617	387	15	2	585	3	606	7e-69	249
rs:WP_039584862	DNA topoisomerase III [Xanthomonas axonopodis].	28.25	662	424	18	1	629	1	644	7e-69	249
rs:WP_024538446	DNA topoisomerase III [Comamonas badia].	29.09	684	404	22	3	627	5	666	7e-69	254
rs:WP_043352648	DNA topoisomerase III [Bacillus cereus].	29.32	706	434	17	3	661	4	691	7e-69	250
rs:WP_043935007	MULTISPECIES: DNA topoisomerase III [Bacillus].	30.11	651	409	15	1	623	1	633	7e-69	250
rs:WP_009463602	MULTISPECIES: DNA topoisomerase III [Alcaligenes].	28.67	722	437	21	3	675	5	697	7e-69	253
rs:WP_035269284	DNA topoisomerase III [Alcaligenes faecalis].	28.67	722	437	21	3	675	5	697	7e-69	253
rs:WP_038007810	DNA topoisomerase, partial [Sutterella wadsworthensis].	26.62	631	401	14	1	578	1	622	7e-69	248
rs:WP_017649217	hypothetical protein [Streptococcus agalactiae].	30.89	722	417	25	3	670	4	697	7e-69	250
rs:WP_034470315	DNA topoisomerase III [Burkholderia zhejiangensis].	29.13	714	436	21	3	673	5	691	7e-69	253
tr:H0PYH2_9RHOO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.29	721	446	23	2	676	13	708	7e-69	253
rs:WP_023085000	hypothetical protein [Pseudomonas aeruginosa].	26.73	666	430	16	1	629	1	645	7e-69	249
rs:WP_026483868	DNA topoisomerase III [Alcaligenes faecalis].	28.67	722	437	21	3	675	5	697	7e-69	253
rs:WP_006691043	DNA topoisomerase [Selenomonas flueggei].	26.68	671	434	17	1	630	1	654	7e-69	250
rs:WP_039602441	DNA topoisomerase III [Pseudomonas putida].	27.85	614	395	14	1	581	1	599	7e-69	249
rs:WP_004270975	DNA topoisomerase III [Lactobacillus curvatus].	29.73	619	387	14	2	610	4	584	7e-69	249
rs:WP_045930539	DNA topoisomerase III [Alcaligenes faecalis].	28.67	722	437	21	3	675	5	697	8e-69	252
tr:R2PQJ8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.63	713	452	18	3	667	5	701	8e-69	250
rs:WP_029442008	DNA topoisomerase III [Bacillus thuringiensis].	30.11	651	409	15	1	623	1	633	8e-69	250
rs:WP_040239307	DNA topoisomerase [Xanthomonas citri].	27.91	731	445	23	3	676	5	710	8e-69	252
rs:WP_002354426	DNA topoisomerase [Enterococcus faecium].	28.27	711	450	18	3	667	4	700	8e-69	250
rs:WP_000540560	DNA topoisomerase III [Bacillus thuringiensis].	29.61	699	428	17	3	655	5	685	8e-69	250
rs:WP_044875527	DNA topoisomerase III [Paenibacillus sp. IHBB 10380].	28.91	671	412	21	3	646	4	636	8e-69	250
tr:S3IA68_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.32	706	434	17	3	661	7	694	8e-69	250
rs:WP_042841609	DNA topoisomerase III [Xanthomonas euvesicatoria].	28.25	662	424	18	1	629	1	644	8e-69	249
rs:WP_025479791	DNA topoisomerase [Enterococcus faecium].	27.51	716	449	18	3	667	4	700	8e-69	250
rs:WP_028610693	DNA topoisomerase III [Paenibacillus harenae].	28.65	754	428	30	3	673	4	730	8e-69	250
rs:WP_025389726	DNA topoisomerase III [Pseudomonas syringae].	27.88	660	429	17	1	629	1	644	8e-69	249
rs:WP_032963652	DNA topoisomerase III [Bordetella hinzii].	27.45	674	441	18	1	641	1	659	8e-69	249
tr:A0A078BQA6_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.19	740	438	27	3	687	5	713	8e-69	252
rs:WP_045366128	DNA topoisomerase III, partial [bacterium endosymbiont of Mortierella elongata FMR23-6].	29.13	721	435	22	3	677	5	695	8e-69	252
tr:D4L9E3_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.65	594	370	15	100	673	9	586	8e-69	248
rs:WP_045469078	DNA topoisomerase III [Burkholderiales bacterium GJ-E10].	27.84	661	435	14	1	640	1	640	8e-69	249
rs:WP_010054218	DNA topoisomerase III [Carnobacterium maltaromaticum].	29.09	629	383	19	3	614	4	586	9e-69	249
rs:WP_024126915	hypothetical protein [Vibrio cholerae].	27.20	750	450	21	1	678	1	726	9e-69	250
rs:WP_034957209	DNA topoisomerase III, partial [Glomeribacter sp. 1016415].	29.13	721	435	22	3	677	5	695	9e-69	251
rs:WP_017640402	DNA topoisomerase III [Pseudomonas sp. 313].	28.51	663	421	18	1	629	1	644	9e-69	249
rs:WP_022396805	DNA topoisomerase III [Akkermansia sp. CAG:344].	28.04	731	453	25	3	683	5	712	9e-69	252
tr:A0A0A1H8R7_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.84	661	435	14	1	640	3	642	9e-69	249
rs:WP_029578156	DNA topoisomerase III [Bordetella hinzii].	27.37	665	427	17	1	629	1	645	9e-69	249
rs:WP_039587992	DNA topoisomerase III [Xanthomonas axonopodis].	28.40	662	423	18	1	629	1	644	9e-69	249
rs:WP_011347486	DNA topoisomerase III [Xanthomonas euvesicatoria].	28.25	662	424	18	1	629	1	644	9e-69	249
rs:WP_022453611	DNA topoisomerase [Prevotella sp. CAG:873].	29.63	648	385	19	65	650	7	645	9e-69	248
rs:WP_019552090	hypothetical protein [Propionispira raffinosivorans].	29.32	665	419	19	1	630	1	649	9e-69	251
rs:WP_009461166	MULTISPECIES: DNA topoisomerase III [Alcaligenes].	28.14	661	427	18	1	629	1	645	9e-69	249
rs:WP_025478649	DNA topoisomerase [Enterococcus faecium].	27.68	708	458	17	3	667	4	700	9e-69	250
rs:WP_031755045	DNA topoisomerase III [Pseudomonas aeruginosa].	28.40	683	430	22	1	646	1	661	9e-69	249
tr:L8PRE1_BACIU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.69	606	381	11	3	581	34	627	9e-69	249
rs:WP_004537740	DNA topoisomerase III [Burkholderia pseudomallei].	29.07	712	439	21	3	673	5	691	1e-68	252
rs:WP_013122335	DNA topoisomerase III [Thiomonas intermedia].	29.19	740	438	27	3	687	5	713	1e-68	252
rs:WP_039956461	DNA topoisomerase III [Bacillus sp. M 2-6].	30.06	682	419	15	1	659	3	649	1e-68	249
rs:WP_025678387	DNA topoisomerase III, partial [Paenibacillus massiliensis].	29.25	612	362	18	3	581	4	577	1e-68	247
tr:L8A4L4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.13	711	451	18	3	667	5	701	1e-68	250
rs:WP_029729038	DNA topoisomerase I [Elizabethkingia anophelis].	31.21	705	423	23	1	673	1	675	1e-68	249
rs:WP_026382163	DNA topoisomerase [Achromobacter xylosoxidans].	28.04	724	448	23	3	676	5	705	1e-68	252
rs:WP_018989244	DNA topoisomerase III [Azoarcus toluclasticus].	28.81	722	442	23	2	676	4	700	1e-68	252
rs:WP_015892060	DNA topoisomerase III [Brevibacillus brevis].	28.14	764	427	28	3	673	4	738	1e-68	250
rs:WP_042852207	DNA topoisomerase III [Escherichia coli].	28.69	617	392	15	1	581	1	605	1e-68	250
rs:WP_042992894	DNA topoisomerase III [Bordetella bronchiseptica].	28.51	663	424	17	1	629	1	647	1e-68	249
rs:WP_016849630	DNA topoisomerase III [Xanthomonas axonopodis].	28.25	662	424	18	1	629	1	644	1e-68	249
rs:WP_009979581	DNA topoisomerase III [Burkholderia pseudomallei].	29.07	712	439	21	3	673	5	691	1e-68	252
rs:WP_022542388	DNA topoisomerase III [Salmonella enterica].	27.20	750	450	21	1	678	1	726	1e-68	250
rs:WP_025480603	DNA topoisomerase [Enterococcus faecium].	28.13	711	451	18	3	667	4	700	1e-68	250
rs:WP_004200734	MULTISPECIES: DNA topoisomerase III [pseudomallei group].	29.07	712	439	21	3	673	5	691	1e-68	252
rs:WP_000366821	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	27.20	750	450	21	1	678	1	726	1e-68	250
tr:V6Q728_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.21	623	385	17	2	610	3	583	1e-68	249
rs:WP_016251036	DNA topoisomerase III [Enterococcus cecorum].	29.59	632	372	19	2	611	3	583	1e-68	249
rs:WP_011850901	DNA topoisomerase III [Burkholderia pseudomallei].	29.07	712	439	21	3	673	5	691	1e-68	252
rs:WP_004525850	MULTISPECIES: DNA topoisomerase III [Burkholderia].	29.07	712	439	21	3	673	5	691	1e-68	252
rs:WP_000366822	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	27.20	750	450	21	1	678	1	726	1e-68	250
rs:WP_024661467	DNA topoisomerase III [Pseudomonas syringae].	28.16	664	423	17	1	629	1	645	1e-68	249
rs:WP_046803444	DNA topoisomerase III [Achromobacter sp. LC458].	28.16	664	425	18	1	629	1	647	1e-68	249
rs:WP_047334783	DNA topoisomerase III [Enterococcus cecorum].	29.14	628	380	16	2	611	3	583	1e-68	249
rs:WP_012315261	DNA topoisomerase III [Pseudomonas putida].	27.85	614	395	14	1	581	1	599	1e-68	248
rs:WP_028790806	DNA topoisomerase III [Tetragenococcus muriaticus].	29.29	618	391	14	2	611	3	582	1e-68	249
tr:I4V807_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.06	682	419	15	1	659	1	647	1e-68	249
rs:WP_042165346	DNA topoisomerase III [Paenibacillus sp. G1].	28.95	722	441	21	3	683	4	694	1e-68	249
rs:WP_025479080	DNA topoisomerase [Enterococcus faecium].	27.97	708	456	17	3	667	4	700	1e-68	250
rs:WP_038798357	DNA topoisomerase III [Burkholderia pseudomallei].	29.07	712	439	21	3	673	5	691	1e-68	252
rs:WP_038729298	DNA topoisomerase III [Burkholderia pseudomallei].	29.07	712	439	21	3	673	5	691	1e-68	252
rs:WP_006675493	DNA topoisomerase III [Paenibacillus dendritiformis].	27.72	754	443	21	3	668	4	743	1e-68	250
rs:WP_009520705	MULTISPECIES: DNA topoisomerase III [Hydrogenophaga].	28.36	751	442	28	3	680	4	731	1e-68	253
rs:WP_013982117	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	27.93	666	424	19	1	630	1	646	1e-68	248
rs:WP_025731506	DNA topoisomerase III [Bacillus ginsengihumi].	30.27	707	438	22	1	676	3	685	1e-68	249
rs:WP_009927580	DNA topoisomerase III [Burkholderia pseudomallei].	29.07	712	439	21	3	673	5	691	1e-68	252
tr:A0A0C6ES95_PSEAI	SubName: Full=Pseudomonas aeruginosa DNA, complete genome, strain: NCGM257 {ECO:0000313|EMBL:BAQ39233.1};	28.21	663	427	17	1	629	1	648	1e-68	248
rs:WP_022484510	DNA topoisomerase [Clostridium sp. CAG:389].	30.33	643	375	17	2	578	4	639	1e-68	248
rs:WP_024634928	MULTISPECIES: DNA topoisomerase [Enterococcus].	27.97	708	456	17	3	667	4	700	1e-68	249
rs:WP_043104890	DNA topoisomerase III [Pseudomonas aeruginosa].	27.03	666	428	17	1	629	1	645	1e-68	248
rs:WP_024420412	DNA topoisomerase III [Pseudomonas avellanae].	28.25	662	424	18	1	629	1	644	1e-68	248
rs:WP_006224636	DNA topoisomerase [Achromobacter piechaudii].	29.06	709	437	21	3	665	5	693	1e-68	251
rs:WP_041013292	DNA topoisomerase III [Pseudomonas xanthomarina].	27.44	616	396	13	1	581	1	600	1e-68	248
rs:WP_036633291	hypothetical protein, partial [Paenibacillus alginolyticus].	30.45	624	392	13	1	590	1	616	1e-68	251
rs:WP_011269736	DNA topoisomerase III [Xanthomonas campestris].	28.25	662	424	18	1	629	1	644	1e-68	248
rs:WP_034061700	hypothetical protein [Pseudomonas aeruginosa].	27.93	709	457	17	3	668	6	703	1e-68	249
rs:WP_036117316	DNA topoisomerase III [Lysinibacillus sphaericus].	29.65	705	450	21	4	675	6	697	1e-68	249
rs:WP_000002937	DNA topoisomerase [Streptococcus agalactiae].	33.77	539	316	12	61	587	14	523	1e-68	245
rs:WP_033874957	DNA topoisomerase III [Pseudomonas aeruginosa].	27.03	666	428	17	1	629	1	645	1e-68	248
tr:L2LKT7_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.97	708	456	17	3	667	5	701	1e-68	249
rs:WP_003451175	DNA topoisomerase III in PFGI-1-like cluster [Pseudomonas pseudoalcaligenes].	26.81	664	432	16	1	629	1	645	1e-68	248
tr:A3NQ18_BURP0	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.07	712	439	21	3	673	42	728	1e-68	252
rs:WP_005877022	DNA topoisomerase III [Enterococcus durans].	28.27	711	450	19	3	667	4	700	1e-68	249
rs:WP_043071384	DNA topoisomerase III [Aneurinibacillus migulanus].	27.92	727	456	19	1	676	1	710	1e-68	249
rs:WP_044786072	DNA topoisomerase III [Paenibacillus polymyxa].	29.74	612	375	20	3	577	4	597	1e-68	250
rs:WP_038809474	DNA topoisomerase [Enterococcus faecium].	27.99	711	452	18	3	667	4	700	2e-68	249
rs:WP_005881848	DNA topoisomerase III [Oxalobacter formigenes].	29.41	714	439	24	3	673	5	696	2e-68	252
rs:WP_039375166	DNA topoisomerase III, partial [Mumia flava].	30.81	620	373	18	3	583	5	607	2e-68	247
rs:WP_036161006	DNA topoisomerase III [Marinomonas ushuaiensis].	29.87	616	391	12	1	581	1	610	2e-68	248
tr:D4M8T1_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.59	696	428	20	1	637	1	679	2e-68	248
rs:WP_044144889	DNA topoisomerase [Enterococcus faecium].	27.97	708	456	17	3	667	4	700	2e-68	249
rs:WP_004189734	DNA topoisomerase III [Burkholderia mallei].	29.13	721	443	22	3	680	5	700	2e-68	251
rs:WP_040465856	DNA topoisomerase III, partial [Erwinia tracheiphila].	29.82	560	352	14	1	530	1	549	2e-68	245
rs:WP_040239258	DNA topoisomerase III [Xanthomonas citri].	28.10	662	425	18	1	629	1	644	2e-68	248
tr:Q3JXE5_BURP1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.07	712	439	21	3	673	41	727	2e-68	252
rs:WP_010726512	DNA topoisomerase III [Enterococcus faecium].	27.79	709	456	17	3	667	4	700	2e-68	249
rs:WP_046614845	DNA topoisomerase III [Pseudomonas putida].	28.06	613	395	14	1	581	1	599	2e-68	248
rs:WP_007870325	DNA topoisomerase III [Polaromonas sp. CF318].	29.11	742	444	26	3	680	4	727	2e-68	253
rs:WP_024889628	DNA topoisomerase III [Luteimonas huabeiensis].	26.88	666	429	17	1	629	1	645	2e-68	248
rs:WP_033078756	DNA topoisomerase III [Thalassotalea sp. ND16A].	29.70	623	382	14	1	581	1	609	2e-68	248
rs:WP_023125205	hypothetical protein [Pseudomonas aeruginosa].	27.03	666	428	17	1	629	1	645	2e-68	248
rs:WP_003290179	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	28.33	660	426	18	1	629	1	644	2e-68	248
rs:WP_034065554	DNA topoisomerase III [Pseudomonas aeruginosa].	28.31	664	425	17	1	629	1	648	2e-68	248
rs:WP_008568568	DNA topoisomerase III [Pseudomonas sp. Chol1].	27.57	613	398	11	1	581	4	602	2e-68	248
rs:WP_038414121	DNA topoisomerase III [Pseudomonas cremoricolorata].	27.50	611	401	13	1	581	1	599	2e-68	248
rs:WP_036204228	hypothetical protein, partial [Lysinibacillus sinduriensis].	29.40	687	414	18	3	655	4	653	2e-68	248
rs:WP_000063789	DNA topoisomerase [Bacillus cereus].	28.23	712	463	17	3	676	5	706	2e-68	249
rs:WP_029514379	DNA topoisomerase III [Paenibacillus polymyxa].	29.74	612	375	20	3	577	4	597	2e-68	250
gp:HE577054_2591	DNA topoisomerase III [Paenibacillus polymyxa M1]	29.74	612	375	20	3	577	7	600	2e-68	250
rs:WP_023095522	hypothetical protein [Pseudomonas aeruginosa].	28.01	689	434	18	1	643	1	673	2e-68	248
rs:WP_016624844	DNA topoisomerase [Enterococcus faecalis].	30.03	716	441	19	3	673	4	704	2e-68	249
rs:WP_026067918	DNA topoisomerase III [Pusillimonas noertemannii].	29.36	729	422	26	3	675	5	696	2e-68	251
rs:WP_034688246	DNA topoisomerase [Enterococcus mundtii].	30.25	714	442	23	3	673	4	704	2e-68	249
tr:G5GKI5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.30	484	278	12	2	473	19	474	2e-68	243
tr:A0A0D6ISH5_ALCXX	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:CKI21189.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CKI21189.1};	28.91	709	438	21	3	665	5	693	2e-68	251
rs:WP_003149058	DNA topoisomerase III [Pseudomonas aeruginosa].	27.93	709	457	17	3	668	6	703	2e-68	249
rs:WP_043886117	DNA topoisomerase III [Paenibacillus polymyxa].	29.74	612	375	20	3	577	4	597	2e-68	250
rs:WP_035470059	DNA topoisomerase III, partial [Gammaproteobacteria bacterium MFB021].	27.54	610	394	16	1	581	1	591	2e-68	247
tr:A0A078MCC0_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.79	705	449	17	3	673	5	690	2e-68	248
rs:WP_039276074	DNA topoisomerase III [Paenibacillus polymyxa].	29.74	612	375	20	3	577	4	597	2e-68	250
rs:WP_039207770	DNA topoisomerase [Anaerovibrio lipolyticus].	28.77	664	408	19	1	616	1	647	2e-68	251
rs:WP_011068071	DNA topoisomerase III [Bifidobacterium longum].	26.69	727	469	21	1	679	160	870	2e-68	251
rs:WP_027592745	DNA topoisomerase III [Pseudomonas sp. LAIL14HWK12:I7].	28.10	612	396	13	1	581	1	599	2e-68	248
rs:WP_031383673	DNA topoisomerase III [Halomonas zincidurans].	28.62	608	390	15	1	581	1	591	2e-68	248
rs:WP_036650398	DNA topoisomerase III [Paenibacillus wynnii].	28.89	637	396	17	3	615	4	607	2e-68	249
rs:WP_031461576	DNA topoisomerase III [Paenibacillus polymyxa].	29.58	612	376	20	3	577	4	597	2e-68	250
rs:WP_017766990	hypothetical protein, partial [Streptococcus agalactiae].	30.75	722	418	25	3	670	4	697	2e-68	248
rs:WP_017382019	hypothetical protein [Paenisporosarcina sp. TG-14].	28.77	709	464	20	3	681	4	701	2e-68	248
tr:T4J8S2_PEPDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.47	594	359	15	65	644	14	567	2e-68	247
rs:WP_025365018	DNA topoisomerase III [Paenibacillus polymyxa].	29.74	612	375	20	3	577	4	597	2e-68	250
rs:WP_025674601	DNA topoisomerase III [Paenibacillus polymyxa].	29.74	612	375	20	3	577	4	597	2e-68	250
rs:WP_046228621	DNA topoisomerase III [Paenibacillus algorifonticola].	28.43	728	439	23	3	684	4	695	2e-68	249
rs:WP_023087320	hypothetical protein [Pseudomonas aeruginosa].	28.36	663	425	17	1	629	1	647	2e-68	248
rs:WP_040053214	DNA topoisomerase III [Burkholderia sp. MR1].	29.18	723	424	23	3	673	5	691	2e-68	251
rs:WP_039431367	DNA topoisomerase III [Xanthomonas vasicola].	28.10	662	425	18	1	629	1	644	2e-68	248
rs:WP_023980686	hypothetical protein [Pseudomonas aeruginosa].	27.93	709	457	17	3	668	6	703	2e-68	249
tr:R9NHH5_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.82	560	352	14	1	530	1	549	2e-68	245
rs:WP_022090677	DNA topoisomerase III [Clostridium sp. CAG:492].	30.93	637	373	18	2	579	4	632	2e-68	247
rs:WP_020651207	DNA topoisomerase III [Solimonas variicoloris].	27.30	674	442	18	1	641	1	659	2e-68	248
rs:WP_036656744	DNA topoisomerase III, partial [Paenibacillus larvae].	28.51	747	431	27	3	673	4	723	2e-68	249
rs:WP_017427723	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	29.74	612	375	20	3	577	4	597	2e-68	250
rs:WP_012248046	DNA topoisomerase III [Bordetella petrii].	28.38	659	427	17	1	629	1	644	2e-68	248
rs:WP_047342146	DNA topoisomerase III [Enterococcus cecorum].	29.75	632	371	19	2	611	3	583	2e-68	248
tr:K1JUJ7_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.62	631	401	14	1	578	1	622	3e-68	248
rs:WP_022446451	DNA topoisomerase III [Faecalibacterium sp. CAG:74].	29.30	604	383	16	3	577	5	593	3e-68	249
rs:WP_016740752	DNA topoisomerase III [Brevibacillus brevis].	28.01	764	428	28	3	673	4	738	3e-68	249
rs:WP_045670938	DNA topoisomerase III [Paenibacillus beijingensis].	27.61	699	429	19	3	657	4	669	3e-68	249
rs:WP_029515045	DNA topoisomerase III [Paenibacillus polymyxa].	29.74	612	375	20	3	577	4	597	3e-68	249
rs:WP_005793094	DNA topoisomerase III [Acidovorax delafieldii].	28.79	660	423	18	1	629	1	644	3e-68	248
rs:WP_023519649	topoisomerase [Enterococcus mundtii].	30.03	716	441	24	3	673	4	704	3e-68	249
rs:WP_001898889	DNA topoisomerase III, partial [Vibrio cholerae].	29.83	580	357	13	41	581	4	572	3e-68	246
rs:WP_031599127	DNA topoisomerase III [Ferrovum myxofaciens].	29.17	665	421	22	1	640	1	640	3e-68	248
rs:WP_015602408	DNA topoisomerase III family protein [Burkholderia thailandensis].	28.71	714	439	21	3	673	5	691	3e-68	251
rs:WP_011379758	DNA topoisomerase III [Nitrosospira multiformis].	28.33	713	442	22	3	671	5	692	3e-68	251
rs:WP_003800563	DNA topoisomerase III [Alcaligenes faecalis].	28.67	722	437	21	3	675	5	697	3e-68	251
rs:WP_009606218	DNA topoisomerase [Turicibacter sp. HGF1].	30.42	697	405	23	3	654	5	666	3e-68	250
rs:WP_024093897	DNA topoisomerase 3 [Paenibacillus larvae].	28.51	747	431	27	3	673	4	723	3e-68	249
rs:WP_035412123	DNA topoisomerase III [Chromohalobacter israelensis].	27.84	643	411	18	1	613	1	620	3e-68	247
rs:WP_033990355	DNA topoisomerase III [Pseudomonas aeruginosa].	27.03	666	428	17	1	629	1	645	3e-68	248
tr:W2E6N4_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.51	747	431	27	3	673	4	723	3e-68	249
rs:WP_004257270	DNA topoisomerase III [Thauera sp. 63].	29.47	716	433	23	2	670	4	694	3e-68	251
rs:WP_043862902	DNA topoisomerase III [Pseudomonas putida].	28.33	660	426	17	1	629	1	644	3e-68	247
rs:WP_042176628	DNA topoisomerase III [Pseudomonas aeruginosa].	28.16	664	426	17	1	629	1	648	3e-68	248
rs:WP_042198563	DNA topoisomerase III [Paenibacillus sp. G4].	28.40	771	430	26	3	673	4	752	3e-68	249
rs:WP_011112497	DNA topoisomerase III [Nitrosomonas europaea].	28.22	723	440	23	2	675	4	696	3e-68	250
rs:WP_025371025	DNA topoisomerase III [Advenella mimigardefordensis].	29.82	731	428	27	3	680	5	703	3e-68	251
rs:WP_025480388	DNA topoisomerase [Enterococcus faecium].	27.68	708	458	17	3	667	4	700	3e-68	249
rs:WP_029092222	hypothetical protein [Brochothrix thermosphacta].	28.05	706	466	17	1	680	1	690	3e-68	248
rs:WP_003474339	DNA topoisomerase III [Xanthomonas translucens].	28.33	660	426	17	1	629	1	644	3e-68	247
rs:WP_006783219	DNA topoisomerase [Turicibacter sanguinis].	30.42	697	405	23	3	654	5	666	3e-68	249
rs:WP_014237640	topoisomerase IA [Azospira oryzae].	30.88	719	408	27	3	663	5	692	3e-68	250
rs:WP_028555965	DNA topoisomerase III [Paenibacillus sp. URHA0014].	27.16	751	448	24	3	671	4	737	3e-68	249
rs:WP_041048759	DNA topoisomerase III [Paenibacillus sp. VKM B-2647].	27.27	770	441	26	3	673	4	753	3e-68	249
rs:WP_046857838	DNA topoisomerase III [Pseudomonas sp. CCOS191].	27.60	616	394	14	1	581	1	599	3e-68	247
rs:WP_013104829	DNA topoisomerase III [Thiomonas arsenitoxydans].	29.05	740	439	27	3	687	5	713	3e-68	250
rs:WP_020566248	DNA topoisomerase III [Burkholderia sp. JPY347].	29.49	712	436	22	3	673	5	691	4e-68	251
rs:WP_004698401	DNA topoisomerase [Veillonella parvula].	28.68	645	402	13	1	612	1	620	4e-68	248
rs:WP_043212213	DNA topoisomerase III [Pseudomonas putida].	29.50	617	380	17	1	581	1	598	4e-68	247
rs:WP_042920648	DNA topoisomerase III [Pseudomonas chloritidismutans].	28.22	659	428	17	1	629	1	644	4e-68	247
rs:WP_020358329	DNA topoisomerase III [Pseudomonas syringae].	28.92	664	418	18	1	629	1	645	4e-68	247
rs:WP_036832004	DNA topoisomerase III, partial [Photobacterium sanctipauli].	30.05	569	355	14	2	537	3	561	4e-68	245
rs:WP_004265528	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	27.27	660	434	17	1	629	1	645	4e-68	247
rs:WP_010735485	DNA topoisomerase III [Enterococcus mundtii].	30.03	716	441	24	3	673	4	704	4e-68	248
rs:WP_007056103	DNA topoisomerase III [Bifidobacterium longum].	26.34	725	470	21	1	677	1	709	4e-68	248
rs:WP_002335350	DNA topoisomerase III [Enterococcus faecium].	27.85	711	453	18	3	667	4	700	4e-68	248
rs:WP_033534309	DNA topoisomerase III [Bordetella trematum].	29.52	725	427	24	3	675	5	697	4e-68	251
rs:WP_034598761	DNA topoisomerase III [Desulfosporosinus sp. HMP52].	29.15	772	427	24	2	676	4	752	4e-68	249
rs:WP_025514931	DNA topoisomerase III [Bordetella trematum].	29.52	725	427	24	3	675	5	697	4e-68	251
rs:WP_043679321	DNA topoisomerase III [Castellaniella defragrans].	29.14	724	431	23	3	675	5	697	4e-68	251
rs:WP_022168305	DNA topoisomerase [Clostridium sp. CAG:221].	28.92	733	440	23	2	679	3	709	4e-68	248
rs:WP_019640460	DNA topoisomerase III [Paenibacillus fonticola].	28.23	673	418	17	3	646	4	640	4e-68	248
rs:WP_036159633	hypothetical protein, partial [Lysinibacillus odysseyi].	30.75	683	410	20	3	655	4	653	4e-68	247
rs:WP_027397710	DNA topoisomerase [Anaerovibrio lipolyticus].	28.77	664	408	19	1	616	1	647	4e-68	250
rs:WP_014125497	DNA topoisomerase III [Tetragenococcus halophilus].	29.23	626	395	15	2	619	3	588	4e-68	248
rs:WP_027350505	DNA topoisomerase III [Halotalea alkalilenta].	27.15	663	431	16	1	629	1	645	4e-68	247
rs:WP_009962376	DNA topoisomerase III [Burkholderia pseudomallei].	29.07	712	439	21	3	673	5	691	4e-68	250
rs:WP_005298337	DNA topoisomerase III [Photobacterium damselae].	30.60	621	374	20	2	581	3	607	4e-68	247
rs:WP_042861184	hypothetical protein [Pseudomonas aeruginosa].	27.79	709	458	17	3	668	6	703	4e-68	248
rs:WP_046833637	DNA topoisomerase III [Xanthomonas axonopodis].	28.12	640	413	16	1	611	1	622	4e-68	247
tr:H8LFB1_ENTFU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.27	711	450	18	3	667	5	701	5e-68	248
rs:WP_018403339	DNA topoisomerase III [Marinobacter lipolyticus].	28.72	665	434	14	1	629	1	661	5e-68	248
rs:WP_010731512	DNA topoisomerase III [Enterococcus faecium].	27.85	711	453	18	3	667	4	700	5e-68	248
rs:WP_025692666	DNA topoisomerase III [Paenibacillus zanthoxyli].	28.37	772	422	29	3	673	4	745	5e-68	249
rs:WP_035450702	DNA topoisomerase III [Lactobacillus composti].	28.12	690	424	21	3	671	5	643	5e-68	247
rs:WP_036929574	DNA topoisomerase I, partial [Prevotella timonensis].	29.15	669	426	19	4	650	5	647	5e-68	247
rs:WP_002295634	DNA topoisomerase [Enterococcus faecium].	27.85	711	453	18	3	667	4	700	5e-68	248
rs:WP_010792172	DNA topoisomerase III [Pseudomonas aeruginosa].	27.73	660	431	17	1	629	1	645	5e-68	247
rs:WP_016954622	DNA topoisomerase III [Catenovulum agarivorans].	31.04	625	377	17	1	581	1	615	5e-68	247
rs:WP_021205487	DNA topoisomerase III [Pseudomonas aeruginosa].	26.97	660	436	16	1	629	1	645	5e-68	247
rs:WP_038995774	DNA topoisomerase III [Pseudomonas putida].	27.68	607	399	12	1	578	1	596	5e-68	246
tr:G9ESR0_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.68	673	430	20	1	640	1	656	5e-68	247
rs:WP_043543456	hypothetical protein [Pseudomonas aeruginosa].	27.79	709	458	17	3	668	6	703	5e-68	248
rs:WP_035968559	DNA topoisomerase III [Burkholderia grimmiae].	28.99	714	437	21	3	673	5	691	5e-68	250
rs:WP_021598073	DNA topoisomerase III protein TopB [Escherichia coli].	27.07	750	451	21	1	678	1	726	5e-68	248
rs:WP_044031624	DNA topoisomerase [Enterococcus faecium].	28.27	711	450	18	3	667	4	700	5e-68	248
rs:WP_042855301	hypothetical protein [Pseudomonas aeruginosa].	27.79	709	458	17	3	668	6	703	6e-68	248
rs:WP_028818553	DNA topoisomerase III [beta proteobacterium SCGC AAA027-C02].	29.04	730	427	24	3	673	16	713	6e-68	250
rs:WP_023657257	DNA topoisomerase III [Pseudomonas aeruginosa].	28.33	660	426	17	1	629	1	644	6e-68	246
rs:WP_010232935	DNA topoisomerase [Clostridium arbusti].	29.56	724	446	24	2	680	3	707	6e-68	248
rs:WP_033836471	DNA topoisomerase III [Xanthomonas citri].	28.10	662	425	18	1	629	1	644	6e-68	246
rs:WP_025479564	DNA topoisomerase [Enterococcus faecium].	28.13	711	451	18	3	667	4	700	6e-68	248
rs:WP_040277052	DNA topoisomerase III [Xanthomonas citri].	28.16	664	422	17	1	629	1	644	6e-68	246
rs:WP_036889370	DNA topoisomerase I [Porphyromonas crevioricanis].	29.10	708	430	24	1	673	2	672	6e-68	247
rs:WP_023093469	hypothetical protein [Pseudomonas aeruginosa].	28.33	660	426	17	1	629	1	644	6e-68	246
rs:WP_028690960	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	28.53	659	426	19	1	629	1	644	6e-68	246
rs:WP_011872847	DNA topoisomerase III [Yersinia ruckeri].	27.07	750	451	21	1	678	1	726	6e-68	248
rs:WP_009459717	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	28.22	659	428	18	1	629	1	644	7e-68	246
rs:WP_023103931	hypothetical protein [Pseudomonas aeruginosa].	28.38	659	427	18	1	629	1	644	7e-68	246
rs:WP_033972349	DNA topoisomerase III [Pseudomonas aeruginosa].	27.77	659	431	17	1	629	1	644	7e-68	246
rs:WP_002331358	DNA topoisomerase III [Enterococcus faecium].	28.13	711	451	19	3	667	4	700	7e-68	248
rs:WP_026383892	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	28.18	660	427	16	1	629	1	644	7e-68	246
tr:E6PWK5_9ZZZZ	SubName: Full=Putative DNA topoisomerase III, bacterial-type {ECO:0000313|EMBL:CBH99312.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBH99312.1};	28.79	719	440	25	3	673	5	699	7e-68	250
rs:WP_020478294	ATP-dependent DNA helicase RecQ [Myxococcus xanthus].	28.30	636	388	16	4	578	29	657	7e-68	254
rs:WP_022833319	DNA topoisomerase III [Cytophagales bacterium B6].	30.84	616	380	19	1	589	1	597	7e-68	245
rs:WP_028590812	DNA topoisomerase III [Paenibacillus panacisoli].	28.87	724	439	25	3	675	4	702	8e-68	248
rs:WP_044477171	DNA topoisomerase III [Paenibacillus sp. GD11].	29.18	634	395	16	3	615	4	604	8e-68	247
rs:WP_009058926	topoisomerase I [Methylacidiphilum fumariolicum].	32.09	617	357	20	2	574	4	602	8e-68	249
rs:WP_002383601	DNA topoisomerase III, partial [Yersinia pestis].	31.07	544	324	20	1	508	1	529	8e-68	243
rs:WP_011391892	DNA topoisomerase [Moorella thermoacetica].	30.45	601	388	14	100	680	1	591	8e-68	246
rs:WP_033947985	DNA topoisomerase III [Pseudomonas aeruginosa].	28.22	659	428	17	1	629	1	644	8e-68	246
rs:WP_033426626	DNA topoisomerase III, partial [Salinicoccus albus].	33.51	555	306	17	107	627	2	527	8e-68	245
rs:WP_043199457	DNA topoisomerase III [Pseudomonas putida].	28.27	612	395	13	1	581	1	599	8e-68	246
rs:WP_025481008	DNA topoisomerase [Enterococcus faecium].	27.49	713	453	18	3	667	4	700	8e-68	248
gp:CP008816_932	DNA topoisomerase III family protein [Enterococcus faecalis ATCC 29212]	29.60	625	373	18	41	644	3	581	9e-68	246
tr:R8NBQ2_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.31	559	334	15	3	527	4	546	9e-68	243
rs:WP_036812954	DNA topoisomerase III [Polaromonas sp. CG9_12].	28.22	776	439	29	3	680	4	759	9e-68	251
rs:WP_019364549	DNA topoisomerase III [Pseudomonas luteola].	27.99	618	408	15	1	590	1	609	9e-68	246
rs:WP_002299813	DNA topoisomerase [Enterococcus faecium].	28.13	711	451	19	3	667	4	700	1e-67	247
rs:WP_029517449	DNA topoisomerase III [Paenibacillus polymyxa].	29.74	612	375	20	3	577	4	597	1e-67	248
rs:WP_014749157	DNA topoisomerase III [Advenella kashmirensis].	29.73	730	430	27	3	680	5	703	1e-67	249
tr:D3LJR4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.13	711	451	18	3	667	5	701	1e-67	247
rs:WP_043064063	DNA topoisomerase III [Aneurinibacillus migulanus].	28.49	716	466	18	1	676	1	710	1e-67	247
rs:WP_015062761	MULTISPECIES: DNA topoisomerase III [Salmonella].	26.25	758	464	18	1	677	1	744	1e-67	248
rs:WP_021264249	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	28.18	660	427	17	1	629	1	644	1e-67	246
tr:Q1DEW9_MYXXD	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.30	636	388	16	4	578	1	629	1e-67	253
rs:WP_038142129	DNA topoisomerase III, partial [Verrucomicrobia bacterium SCGC AAA164-E04].	28.51	740	424	25	3	680	5	701	1e-67	249
rs:WP_013660507	DNA topoisomerase III [Marinomonas mediterranea].	30.71	622	376	16	1	581	1	608	1e-67	246
rs:WP_012423151	DNA topoisomerase [Clostridium botulinum].	28.14	732	446	22	2	680	3	707	1e-67	247
rs:WP_017825599	DNA topoisomerase [Clostridium botulinum].	28.10	733	445	22	2	680	3	707	1e-67	247
rs:WP_044293632	DNA topoisomerase III [Pseudomonas amygdali].	28.46	664	421	17	1	629	1	645	1e-67	246
rs:WP_002318121	DNA topoisomerase [Enterococcus faecium].	28.13	711	451	18	3	667	4	700	1e-67	247
rs:WP_017707803	DNA topoisomerase III [Pseudomonas syringae].	28.11	644	413	16	1	613	1	625	1e-67	246
rs:WP_043070392	hypothetical protein, partial [Aneurinibacillus migulanus].	30.49	610	377	15	1	573	1	600	1e-67	247
rs:WP_034229263	hypothetical protein, partial [Lachnospiraceae bacterium 3-1].	30.83	587	364	13	105	673	2	564	1e-67	244
rs:WP_023124708	hypothetical protein [Pseudomonas aeruginosa].	28.44	661	424	18	1	629	1	644	1e-67	246
tr:R3TLQ7_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.46	636	392	18	28	644	5	596	1e-67	246
rs:WP_023434789	DNA topoisomerase III [Pseudomonas aeruginosa].	28.42	665	423	17	1	629	1	648	1e-67	246
rs:WP_038705838	DNA topoisomerase III [Pseudomonas mosselii].	27.44	616	395	14	1	581	1	599	1e-67	245
rs:WP_013964628	DNA topoisomerase III [Nitrosomonas sp. Is79A3].	28.37	719	438	24	3	673	5	694	1e-67	249
rs:WP_013332057	DNA topoisomerase III [Halomonas elongata].	28.17	607	394	14	1	581	1	591	1e-67	245
rs:WP_023893457	DNA topoisomerase III [Salmonella enterica].	26.25	758	464	19	1	677	1	744	1e-67	248
tr:C7X9U5_9PORP	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEU51022.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EEU51022.1};	29.56	653	421	20	47	677	5	640	1e-67	246
rs:WP_035604997	DNA topoisomerase III [Haloferula sp. BvORR071].	30.24	678	405	23	3	632	5	662	1e-67	249
rs:WP_003478477	DNA topoisomerase [Clostridium perfringens].	27.73	732	461	22	2	685	3	714	1e-67	246
tr:W7YS18_9BACT	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:GAF05224.1};	32.38	522	309	15	1	502	1	498	1e-67	242
rs:WP_024008203	DNA topoisomerase III [Pseudomonas aeruginosa].	27.77	659	431	17	1	629	1	644	1e-67	246
rs:WP_046079688	DNA topoisomerase III [Halomonas sp. HG01].	27.80	615	386	17	1	581	1	591	1e-67	246
rs:WP_035063737	DNA topoisomerase III [Carnobacterium maltaromaticum].	28.93	629	384	19	3	614	4	586	1e-67	246
rs:WP_023988966	DNA topoisomerase III [Paenibacillus polymyxa].	29.58	612	376	20	3	577	4	597	1e-67	248
rs:WP_007717774	DNA topoisomerase III [Brevibacillus sp. BC25].	27.80	759	436	26	3	673	4	738	1e-67	247
rs:WP_028686538	DNA topoisomerase III [Pseudomonas fulva].	27.45	612	400	13	1	581	1	599	1e-67	245
tr:D4X4C7_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.72	718	458	20	3	676	4	704	1e-67	249
rs:WP_002326518	DNA topoisomerase III [Enterococcus faecium].	28.27	711	450	18	3	667	4	700	2e-67	247
tr:V4ZF16_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.86	700	431	21	26	680	3	680	2e-67	248
rs:WP_019850806	DNA topoisomerase III [Desulfitobacterium sp. PCE1].	26.79	769	456	21	3	676	5	761	2e-67	248
rs:WP_039882454	DNA topoisomerase [Achromobacter piechaudii].	27.72	718	458	20	3	676	5	705	2e-67	248
rs:WP_008246963	DNA topoisomerase III [Limnobacter sp. MED105].	29.14	731	436	26	2	680	8	708	2e-67	248
tr:S6U3B9_PSESF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.55	634	404	16	31	629	14	633	2e-67	245
rs:WP_011507443	DNA topoisomerase III [Chromohalobacter salexigens].	27.84	643	411	18	1	613	1	620	2e-67	245
rs:WP_007781693	DNA topoisomerase III [Desulfosporosinus youngiae].	28.14	764	441	21	3	676	5	750	2e-67	247
tr:W7WFC9_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.52	616	361	20	3	565	5	606	2e-67	244
rs:WP_007416564	DNA topoisomerase III [Pedosphaera parvula].	28.57	714	441	21	3	673	5	692	2e-67	248
tr:A0A078BLX7_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.28	545	352	10	84	611	6	539	2e-67	244
tr:A0A011RAP0_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.27	731	457	21	2	677	4	707	2e-67	248
rs:WP_022243205	DNA topoisomerase [Roseburia sp. CAG:45].	26.78	758	465	19	3	680	5	752	2e-67	250
rs:WP_005878079	DNA topoisomerase III [Oxalobacter formigenes].	29.43	717	435	25	3	673	5	696	2e-67	249
rs:WP_029194220	DNA topoisomerase III [Paenibacillus alginolyticus].	26.82	757	444	26	3	673	4	736	2e-67	247
rs:WP_003120035	DNA topoisomerase III [Pseudomonas aeruginosa].	28.53	659	426	17	1	629	1	644	2e-67	245
rs:WP_024642909	DNA topoisomerase III [Pseudomonas syringae].	27.88	624	405	14	1	592	1	611	2e-67	245
rs:WP_021663330	DNA topoisomerase [Porphyromonas gingivalis].	29.71	700	449	21	1	677	1	680	2e-67	246
rs:WP_046809689	DNA topoisomerase III [Pseudomonas psychrophila].	28.06	613	393	12	1	580	1	598	2e-67	244
rs:WP_028319719	DNA topoisomerase III [Desulfobulbus elongatus].	28.63	723	440	23	3	679	5	697	2e-67	248
rs:WP_041877376	DNA topoisomerase I [Pedobacter sp. NL19].	30.05	609	384	16	1	582	1	594	2e-67	244
rs:WP_013310504	DNA topoisomerase III [Paenibacillus polymyxa].	29.74	612	375	20	3	577	4	597	2e-67	247
rs:WP_014902554	DNA topoisomerase III [Desulfosporosinus meridiei].	28.66	764	437	25	2	676	4	748	2e-67	247
rs:WP_003286333	DNA topoisomerase III [Pseudomonas stutzeri].	27.57	613	398	11	1	581	4	602	2e-67	244
rs:WP_002316073	DNA topoisomerase [Enterococcus faecium].	27.39	712	455	18	3	667	4	700	2e-67	246
rs:WP_024889541	DNA topoisomerase III [Luteimonas huabeiensis].	28.22	684	432	21	1	646	1	663	2e-67	245
rs:WP_016498844	DNA topoisomerase III [Pseudomonas putida].	28.10	612	396	13	1	581	1	599	2e-67	244
tr:A0A061NAW1_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.81	663	429	16	41	673	29	678	2e-67	246
rs:WP_014184172	DNA topoisomerase III [Desulfosporosinus orientis].	28.02	753	445	21	3	676	5	739	2e-67	246
rs:WP_039271318	DNA topoisomerase III [Paenibacillus polymyxa].	29.58	612	376	20	3	577	4	597	2e-67	247
rs:WP_033986546	DNA topoisomerase III [Pseudomonas aeruginosa].	27.03	666	428	17	1	629	1	645	2e-67	245
tr:E4IYX6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.49	713	453	18	3	667	5	701	2e-67	246
rs:WP_042421644	DNA topoisomerase III [Comamonas granuli].	29.21	671	388	22	3	611	5	650	2e-67	249
rs:WP_007828684	DNA topoisomerase III [Variovorax sp. CF313].	28.87	755	438	26	3	680	5	737	2e-67	249
rs:WP_002636140	ATP-dependent DNA helicase RecQ [Myxococcus sp. (contaminant ex DSM 436)].	27.52	636	393	15	4	578	29	657	2e-67	252
rs:WP_006410664	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	26.88	677	441	17	1	641	1	659	2e-67	245
rs:WP_009618204	DNA topoisomerase III [Pseudomonas sp. M1].	27.39	679	435	19	1	641	1	659	3e-67	245
rs:WP_012419017	DNA topoisomerase III [Bordetella avium].	28.51	726	433	23	3	675	5	697	3e-67	248
rs:WP_036172716	DNA topoisomerase III [Massilia sp. 9096].	29.03	720	443	24	3	679	5	699	3e-67	248
rs:WP_043223335	DNA topoisomerase III [Bordetella hinzii].	26.86	644	423	14	1	614	1	626	3e-67	245
rs:WP_034006787	DNA topoisomerase III [Pseudomonas aeruginosa].	27.62	659	432	17	1	629	1	644	3e-67	245
rs:WP_025478277	DNA topoisomerase [Enterococcus faecium].	28.67	715	451	20	3	673	4	703	3e-67	246
rs:WP_019828878	DNA topoisomerase III [Pseudomonas sp. CF149].	28.06	613	393	12	1	580	1	598	3e-67	244
rs:WP_002321299	DNA topoisomerase [Enterococcus faecium].	27.49	713	453	18	3	667	4	700	3e-67	246
tr:A0A085WJV1_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.81	640	391	15	1	578	1	631	3e-67	251
tr:F7SZR1_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.65	705	418	23	26	675	3	677	3e-67	248
rs:WP_038625712	DNA topoisomerase III [Pantoea sp. PSNIH2].	27.12	660	435	17	1	629	1	645	3e-67	244
rs:WP_021665030	DNA topoisomerase [Porphyromonas gingivalis].	29.06	709	456	21	1	684	1	687	3e-67	245
rs:WP_003403627	DNA topoisomerase III [Pseudomonas syringae].	27.72	624	406	14	1	592	1	611	3e-67	244
rs:WP_014281498	DNA topoisomerase III [Paenibacillus terrae].	29.90	612	374	20	3	577	4	597	3e-67	246
tr:A0A096HU54_LACPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.51	610	386	16	3	581	4	600	3e-67	245
tr:W6LQR6_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.75	663	390	16	4	586	5	658	3e-67	251
rs:WP_027961016	DNA topoisomerase III [Halomonas halodenitrificans].	27.51	607	398	13	1	581	1	591	3e-67	244
rs:WP_038472828	DNA topoisomerase III, partial [Acidithiobacillus caldus].	29.37	572	366	14	36	576	13	577	3e-67	243
rs:WP_033700641	DNA topoisomerase, partial [Enterococcus faecium].	29.82	654	394	20	3	611	4	637	3e-67	244
rs:WP_006485782	DNA topoisomerase III [Burkholderia cenocepacia].	28.43	700	434	22	26	680	3	680	3e-67	248
rs:WP_027365920	DNA topoisomerase III, partial [Desulfotomaculum alcoholivorax].	33.20	515	311	14	3	496	4	506	3e-67	241
rs:WP_032572319	DNA topoisomerase I [Bacteroides fragilis].	28.49	709	439	25	1	676	1	674	3e-67	245
tr:F3GEC0_PSESJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	27.45	623	409	13	1	592	1	611	3e-67	244
rs:WP_022334396	DNA topoisomerase [Clostridium sp. CAG:452].	30.02	643	376	18	2	578	3	637	3e-67	244
rs:WP_024677692	DNA topoisomerase III [Pseudomonas syringae].	28.73	644	409	16	1	613	1	625	4e-67	244
rs:WP_024139110	DNA topoisomerase III [Salmonella enterica].	26.32	756	466	19	1	677	1	744	4e-67	246
rs:WP_013648723	DNA topoisomerase III [Nitrosomonas sp. AL212].	28.87	717	441	25	3	675	5	696	4e-67	247
rs:WP_034431315	ATP-dependent DNA helicase RecQ, partial [Candidatus Contendobacter odensis].	27.75	663	390	16	4	586	3	656	4e-67	250
rs:WP_041084686	DNA topoisomerase [Clostridium botulinum].	27.97	733	446	22	2	680	3	707	4e-67	245
rs:WP_035119416	DNA topoisomerase III [Cohnella panacarvi].	27.15	744	431	25	3	652	4	730	4e-67	246
rs:WP_020311915	DNA topoisomerase III [Megasphaera sp. NM10].	27.69	668	428	17	3	633	4	653	4e-67	245
rs:WP_002307526	DNA topoisomerase [Enterococcus faecium].	27.71	711	454	18	3	667	4	700	4e-67	246
rs:WP_012450313	DNA topoisomerase [Clostridium botulinum].	27.97	733	446	22	2	680	3	707	4e-67	245
rs:WP_043293089	DNA topoisomerase III, partial [Burkholderia vietnamiensis].	29.05	723	449	21	2	681	4	705	4e-67	247
rs:WP_031538172	DNA topoisomerase [Bacillus sp. MB2021].	30.22	728	434	26	1	679	1	703	4e-67	245
rs:WP_044146630	DNA topoisomerase [Enterococcus faecium].	28.67	715	451	20	3	673	4	703	4e-67	246
rs:WP_010731122	DNA topoisomerase III [Enterococcus faecium].	27.71	711	454	18	3	667	4	700	4e-67	245
rs:WP_015276251	DNA topoisomerase III [Pseudomonas stutzeri].	27.11	616	398	13	1	581	1	600	5e-67	244
rs:WP_041501265	topoisomerase I [Lactobacillus heilongjiangensis].	28.93	719	446	21	3	676	4	702	5e-67	245
rs:WP_019018703	DNA topoisomerase III [Halomonas lutea].	26.61	654	430	17	1	622	1	636	5e-67	244
rs:WP_024647908	DNA topoisomerase III [Pseudomonas syringae].	27.45	623	409	13	1	592	1	611	5e-67	244
rs:WP_032660787	DNA topoisomerase III [Pseudomonas syringae].	27.45	623	409	13	1	592	1	611	5e-67	244
rs:WP_003679507	DNA topoisomerase III [Lactobacillus coryniformis].	30.67	626	369	17	3	614	4	578	5e-67	244
tr:A4JV87_BURVG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.05	723	449	21	2	681	4	705	5e-67	246
rs:WP_002338048	DNA topoisomerase III, partial [Enterococcus faecium].	28.53	687	428	17	31	667	4	677	5e-67	245
tr:A0A014MIW0_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.63	709	411	23	27	666	16	698	5e-67	248
rs:WP_012552822	DNA topoisomerase III [Lactobacillus casei].	29.77	608	387	15	3	581	4	600	5e-67	245
rs:WP_006439101	DNA topoisomerase III [[Clostridium] hiranonis].	29.01	655	399	20	3	631	5	619	5e-67	245
rs:WP_040287707	DNA topoisomerase III [Sporosarcina koreensis].	28.57	721	446	23	3	675	4	703	5e-67	245
tr:J7CXS9_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.67	715	451	20	3	673	21	720	5e-67	246
rs:WP_038493688	DNA topoisomerase III [Collimonas arenae].	28.87	724	444	24	3	680	5	703	5e-67	247
rs:WP_019924412	DNA topoisomerase III [Duganella zoogloeoides].	28.97	725	443	24	3	679	5	705	5e-67	248
rs:WP_010008973	DNA topoisomerase III [Lactobacillus coryniformis].	30.67	626	369	17	3	614	4	578	5e-67	244
rs:WP_043046559	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	28.64	618	396	13	2	581	3	613	6e-67	243
rs:WP_031906002	DNA topoisomerase III [Staphylococcus aureus].	29.93	715	440	20	3	680	4	694	6e-67	244
rs:WP_016853417	DNA topoisomerase [Enterococcus faecium].	27.85	711	453	18	3	667	4	700	6e-67	245
rs:WP_011533418	DNA topoisomerase III [Pseudomonas entomophila].	27.80	615	394	15	1	581	1	599	6e-67	243
rs:WP_044545931	DNA topoisomerase I, partial [Parabacteroides distasonis].	27.71	599	406	9	1	582	1	589	6e-67	242
rs:WP_003455196	DNA topoisomerase [Clostridium perfringens].	27.73	732	461	23	2	685	3	714	6e-67	245
rs:WP_036081149	DNA topoisomerase III [Lysinibacillus boronitolerans].	28.84	704	457	20	4	675	6	697	6e-67	244
rs:WP_034164950	DNA topoisomerase III [Edwardsiella tarda].	28.10	751	442	23	1	678	1	726	6e-67	245
rs:WP_010721414	DNA topoisomerase III [Enterococcus faecium].	27.71	711	454	18	3	667	4	700	6e-67	245
rs:WP_042986068	DNA topoisomerase I, partial [Bacteroides fragilis].	30.27	664	410	22	48	684	1	638	6e-67	243
rs:WP_019036784	DNA topoisomerase I, partial [Prevotella amnii].	30.97	620	343	21	4	575	5	587	6e-67	242
tr:A0A098AZW1_DESHA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.97	775	440	25	3	676	5	754	6e-67	246
rs:WP_010798937	DNA topoisomerase III [Pseudomonas sp. HPB0071].	28.10	605	399	14	1	578	1	596	6e-67	243
rs:WP_004457833	DNA topoisomerase [Clostridium perfringens].	27.60	732	462	22	2	685	3	714	7e-67	244
rs:WP_038398917	DNA topoisomerase [Enterococcus faecium].	28.67	715	451	20	3	673	4	703	7e-67	245
rs:WP_003374314	DNA topoisomerase [Clostridium botulinum].	27.83	733	447	22	2	680	3	707	7e-67	244
rs:WP_016781518	DNA topoisomerase III [Pseudomonas fragi].	27.73	613	395	12	1	580	1	598	7e-67	243
tr:E8REX8_DESPD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.14	720	433	24	3	679	5	697	7e-67	246
rs:WP_020365500	DNA topoisomerase III, partial [Staphylococcus epidermidis].	30.12	684	402	22	3	634	4	663	8e-67	244
rs:WP_011010711	DNA topoisomerase [Clostridium perfringens].	27.60	732	462	22	2	685	3	714	8e-67	244
rs:WP_002346936	DNA topoisomerase III [Enterococcus faecium].	27.71	711	454	18	3	667	4	700	8e-67	244
tr:C7GHN5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.88	574	342	17	123	673	2	549	8e-67	241
rs:WP_044311497	DNA topoisomerase III [Pseudomonas syringae].	27.61	623	408	14	1	592	1	611	8e-67	243
rs:WP_006714537	DNA topoisomerase III [Vibrio ichthyoenteri].	28.24	648	413	17	1	617	1	627	8e-67	243
rs:WP_024638443	DNA topoisomerase III [Pseudomonas syringae].	27.72	624	406	14	1	592	1	611	8e-67	243
rs:WP_012345266	DNA topoisomerase III [Leptothrix cholodnii].	29.75	689	370	24	3	611	5	659	8e-67	247
rs:WP_044188344	ATP-dependent DNA helicase RecQ [Hyalangium minutum].	27.79	637	389	15	4	578	37	664	8e-67	250
rs:WP_010777183	DNA topoisomerase III [Enterococcus faecium].	27.71	711	454	18	3	667	4	700	9e-67	244
rs:WP_003481996	DNA topoisomerase [Clostridium perfringens].	27.60	732	462	22	2	685	3	714	9e-67	244
rs:WP_043770622	DNA topoisomerase III [Desulfobulbus propionicus].	30.14	720	433	24	3	679	17	709	9e-67	246
rs:WP_034611031	DNA topoisomerase III [Desulfosporosinus sp. Tol-M].	27.73	761	451	22	3	676	5	753	9e-67	245
rs:WP_042840726	DNA topoisomerase III, partial [Salmonella enterica].	31.65	534	322	19	1	502	1	523	9e-67	240
rs:WP_017211802	MULTISPECIES: DNA topoisomerase [Clostridium].	27.83	733	446	21	2	679	3	707	9e-67	244
rs:WP_020306649	DNA topoisomerase III [Pseudomonas syringae].	28.08	666	421	17	1	629	1	645	9e-67	243
rs:WP_039589247	DNA topoisomerase III [Pseudomonas frederiksbergensis].	27.59	609	397	13	1	578	1	596	9e-67	243
rs:WP_033872262	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	26.86	618	405	13	1	585	1	604	9e-67	242
rs:WP_028993922	DNA topoisomerase III [Azonexus hydrophilus].	27.34	728	437	21	2	669	4	699	9e-67	246
rs:WP_005740008	DNA topoisomerase III [Pseudomonas amygdali].	27.90	663	426	16	1	629	1	645	1e-66	243
rs:WP_022412826	DNA topoisomerase [Clostridium sp. CAG:470].	29.75	652	376	18	2	578	4	648	1e-66	243
rs:WP_026686798	DNA topoisomerase III [Azovibrio restrictus].	27.73	732	447	23	2	676	4	710	1e-66	246
rs:WP_044648482	DNA topoisomerase III [Paenibacillus terrae].	29.90	612	374	20	3	577	4	597	1e-66	245
tr:T4JS35_PEPDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.51	716	449	19	3	667	4	700	1e-66	244
rs:WP_012552651	MULTISPECIES: topoisomerase III [Bacillus cereus group].	30.17	706	435	23	3	664	5	696	1e-66	244
rs:WP_005667883	DNA topoisomerase III [Massilia timonae].	28.71	721	446	23	3	680	5	700	1e-66	246
rs:WP_010726014	DNA topoisomerase III [Enterococcus faecium].	27.71	711	454	18	3	667	4	700	1e-66	244
rs:WP_046235877	DNA topoisomerase III [Pseudomonas syringae pv. coryli].	27.61	623	408	14	1	592	1	611	1e-66	243
rs:WP_028692401	DNA topoisomerase III [Pseudomonas mosselii].	27.64	615	395	14	1	581	1	599	1e-66	243
rs:WP_003090102	DNA topoisomerase III [Pseudomonas aeruginosa].	28.46	664	424	18	1	629	1	648	1e-66	243
rs:WP_035785837	DNA topoisomerase [Clostridium botulinum].	28.40	743	430	24	2	680	3	707	1e-66	244
rs:WP_043859254	DNA topoisomerase III [Staphylococcus aureus].	30.95	685	400	24	3	647	4	655	1e-66	244
rs:WP_023124357	hypothetical protein [Pseudomonas aeruginosa].	27.34	662	431	17	1	629	1	645	1e-66	243
rs:WP_000542403	topoisomerase III [Bacillus cereus].	30.17	706	435	23	3	664	5	696	1e-66	244
rs:WP_014794498	DNA topoisomerase III [Desulfitobacterium dehalogenans].	26.75	770	455	22	3	676	5	761	1e-66	245
rs:WP_000542404	MULTISPECIES: topoisomerase III [Bacillus cereus group].	30.17	706	435	23	3	664	5	696	1e-66	244
rs:WP_031877274	DNA topoisomerase III, partial [Staphylococcus aureus].	32.36	547	337	15	3	534	4	532	1e-66	240
rs:WP_041894446	DNA topoisomerase [Clostridium beijerinckii].	27.83	733	446	21	2	679	3	707	1e-66	244
rs:WP_011591016	DNA topoisomerase [Clostridium perfringens].	27.60	732	462	22	2	685	3	714	1e-66	244
rs:WP_003461793	DNA topoisomerase [Clostridium perfringens].	27.60	732	462	22	2	685	3	714	1e-66	244
rs:WP_034065220	DNA topoisomerase III [Pseudomonas aeruginosa].	28.38	659	427	19	1	629	1	644	1e-66	243
rs:WP_034932201	DNA topoisomerase III [Candidatus Accumulibacter sp. SK-12].	27.20	728	446	24	2	673	4	703	1e-66	246
rs:WP_034820674	DNA topoisomerase, partial [[Eubacterium] nodatum].	33.67	496	289	13	3	486	4	471	1e-66	238
rs:WP_033873175	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	26.79	616	408	12	1	585	1	604	1e-66	241
rs:WP_003451558	DNA topoisomerase [Clostridium perfringens].	27.46	732	463	22	2	685	3	714	1e-66	244
rs:WP_010206575	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	28.46	664	421	17	1	629	1	645	1e-66	243
rs:WP_023842835	DNA topoisomerase [Burkholderia sp. M701].	28.90	737	437	24	3	675	5	718	1e-66	246
rs:WP_028784638	DNA topoisomerase III [Thalassobacillus devorans].	29.08	705	425	19	3	658	5	683	1e-66	244
rs:WP_043052453	DNA topoisomerase [Streptococcus equi].	30.81	727	411	26	3	670	4	697	1e-66	244
rs:WP_025722650	DNA topoisomerase III [Paenibacillus polymyxa].	29.58	612	376	20	3	577	4	597	1e-66	245
rs:WP_013816520	DNA topoisomerase I [Porphyromonas gingivalis].	29.06	709	456	21	1	684	1	687	1e-66	243
rs:WP_017768494	hypothetical protein [Streptococcus agalactiae].	30.81	727	411	26	3	670	4	697	1e-66	244
rs:WP_004281998	conjugal transfer protein TraE [Acinetobacter lwoffii].	30.42	720	425	25	2	669	3	698	1e-66	244
rs:WP_016526810	DNA topoisomerase [Lactobacillus plantarum].	29.24	619	398	15	3	592	4	611	1e-66	244
rs:WP_034564290	DNA topoisomerase III [Carnobacterium gallinarum].	28.46	629	387	18	3	614	4	586	1e-66	243
tr:A0A069DAW1_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.00	610	375	19	3	577	4	596	1e-66	245
rs:WP_014216307	DNA topoisomerase III [Pediococcus claussenii].	29.61	608	388	15	3	581	4	600	2e-66	243
rs:WP_002338430	DNA topoisomerase III, partial [Enterococcus faecium].	29.53	657	402	18	65	675	3	644	2e-66	242
rs:WP_031597904	DNA topoisomerase III, partial [Pseudomonas savastanoi].	28.62	608	399	13	1	581	1	600	2e-66	241
rs:WP_026195590	topoisomerase I [Verrucomicrobium sp. 3C].	27.61	728	454	24	3	684	5	705	2e-66	246
rs:WP_011810900	DNA topoisomerase III [Verminephrobacter eiseniae].	28.69	732	443	25	3	670	5	721	2e-66	246
rs:WP_041487101	DNA topoisomerase III [[Clostridium] sticklandii].	29.83	704	413	22	3	636	5	697	2e-66	244
rs:WP_031417620	DNA topoisomerase III [Lysinibacillus sphaericus].	28.21	709	467	16	1	677	1	699	2e-66	243
rs:WP_044478733	DNA topoisomerase III [Paenibacillus sp. GD11].	28.10	758	443	25	3	684	4	735	2e-66	244
rs:WP_027916196	DNA topoisomerase III [Pseudomonas sp. URMO17WK12:I11].	27.45	612	400	13	1	581	1	599	2e-66	242
rs:WP_009080346	DNA topoisomerase, partial [Peptostreptococcaceae bacterium AS15].	33.40	497	285	13	1	480	1	468	2e-66	238
tr:B1XSN4_POLNS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.61	727	438	22	3	675	23	722	2e-66	246
rs:WP_042128274	DNA topoisomerase III [Paenibacillus sp. FSL R5-0345].	26.83	753	450	23	3	673	4	737	2e-66	244
rs:WP_037040786	DNA topoisomerase III [Pseudomonas sp. BAY1663].	27.34	662	431	17	1	629	1	645	2e-66	243
rs:WP_001631999	DNA topoisomerase III [Staphylococcus aureus].	29.17	713	448	19	3	680	4	694	2e-66	243
rs:WP_013520941	DNA topoisomerase III [Alicycliphilus denitrificans].	29.48	675	381	25	3	611	5	650	2e-66	246
tr:C0FRI7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	26.46	752	471	19	6	683	1	744	2e-66	246
rs:WP_019411547	DNA topoisomerase III [Pseudomonas psychrophila].	28.06	613	393	12	1	580	1	598	2e-66	242
rs:WP_022473457	DNA topoisomerase [Sutterella sp. CAG:521].	29.53	718	434	25	3	676	6	695	2e-66	245
rs:WP_036185771	hypothetical protein, partial [Lysinibacillus manganicus].	29.68	684	416	21	3	655	5	654	2e-66	243
rs:WP_047068304	DNA topoisomerase III [Brevibacillus formosus].	26.78	758	445	23	3	673	4	738	2e-66	244
rs:WP_027015253	DNA topoisomerase III [Comamonas composti].	28.36	663	426	17	1	629	1	648	2e-66	243
rs:WP_039607434	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	27.84	661	429	16	1	629	1	645	2e-66	243
rs:WP_011168879	DNA topoisomerase III [Pseudomonas savastanoi].	27.61	623	408	14	1	592	1	611	2e-66	242
rs:WP_023534787	DNA topoisomerase III [Pseudomonas putida].	27.36	614	398	13	1	581	1	599	2e-66	242
rs:WP_027996519	DNA topoisomerase III [Simplicispira psychrophila].	28.48	741	421	28	3	666	5	713	2e-66	246
rs:WP_002336984	DNA topoisomerase III [Enterococcus faecium].	28.67	715	451	20	3	673	4	703	2e-66	244
rs:WP_046984497	DNA topoisomerase III [Thermomonas brevis].	26.99	667	432	17	1	629	1	650	2e-66	243
rs:WP_010777139	DNA topoisomerase III [Enterococcus faecium].	28.67	715	451	20	3	673	4	703	2e-66	244
rs:WP_014008078	DNA topoisomerase III [Collimonas fungivorans].	28.73	724	445	24	3	680	5	703	2e-66	246
tr:H1HVV1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.01	587	332	19	1	536	3	567	2e-66	240
rs:WP_016981353	DNA topoisomerase III [Pseudomonas amygdali].	27.45	623	409	14	1	592	1	611	2e-66	242
rs:WP_027821235	DNA topoisomerase III [Lactobacillus plantarum].	29.61	608	388	15	3	581	4	600	2e-66	243
rs:WP_024960098	DNA topoisomerase III [Pseudomonas syringae].	27.29	623	410	13	1	592	1	611	2e-66	242
rs:WP_026835960	DNA topoisomerase III [Eubacterium xylanophilum].	30.72	651	368	24	2	581	4	642	2e-66	243
rs:WP_002324101	DNA topoisomerase III [Enterococcus faecium].	28.67	715	451	20	3	673	4	703	2e-66	244
tr:C2HAZ4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.53	715	452	20	3	673	21	720	2e-66	244
rs:WP_045724140	DNA topoisomerase [Clostridium baratii].	29.10	725	448	23	2	680	3	707	2e-66	243
rs:WP_003432932	DNA topoisomerase III [Pseudomonas syringae].	27.29	623	410	15	1	592	1	611	2e-66	242
tr:F6IW93_LACPE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.44	608	389	14	3	581	4	600	2e-66	243
rs:WP_023434592	DNA topoisomerase III [Pseudomonas aeruginosa].	27.12	660	435	17	1	629	1	645	2e-66	242
rs:WP_039445299	conjugal transfer protein TraE [Xanthomonas vasicola].	29.20	654	405	18	1	614	1	636	2e-66	243
rs:WP_007130011	DNA topoisomerase III [Paenibacillus lactis].	27.03	751	452	24	3	673	4	738	2e-66	244
rs:WP_011267536	DNA topoisomerase III [Pseudomonas syringae].	27.72	624	406	14	1	592	1	611	2e-66	242
rs:WP_039830311	DNA topoisomerase III, partial [Pandoraea sp. B-6].	28.73	717	442	22	3	673	5	698	2e-66	245
rs:WP_000859496	DNA topoisomerase III [Staphylococcus aureus].	29.79	715	441	20	3	680	4	694	2e-66	243
rs:WP_043400217	ATP-dependent DNA helicase RecQ [Cystobacter violaceus].	27.52	665	408	17	1	606	1	650	2e-66	249
rs:WP_016370345	DNA topoisomerase III [Lactobacillus paracasei].	29.84	610	388	16	1	581	2	600	2e-66	243
rs:WP_031838445	DNA topoisomerase III, partial [Staphylococcus aureus].	33.33	534	314	14	100	615	1	510	2e-66	241
rs:WP_040012714	DNA topoisomerase, partial [Peptostreptococcaceae bacterium ACC19a].	33.95	483	281	12	1	472	1	456	2e-66	237
rs:WP_024635188	DNA topoisomerase [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	2e-66	243
rs:WP_023043374	DNA topoisomerase III, partial [Photorhabdus temperata].	27.18	721	429	21	30	678	5	701	2e-66	243
rs:WP_003470899	DNA topoisomerase [Clostridium perfringens].	27.46	732	463	22	2	685	3	714	2e-66	243
rs:WP_044930417	DNA topoisomerase III, partial [Clostridium sp. M62/1].	30.43	493	301	14	1	471	1	473	2e-66	237
rs:WP_002351810	DNA topoisomerase III, partial [Enterococcus faecium].	29.69	650	400	19	3	611	4	637	2e-66	241
rs:WP_031755005	DNA topoisomerase III [Pseudomonas aeruginosa].	27.12	660	435	17	1	629	1	645	2e-66	242
rs:WP_007349726	DNA topoisomerase III [Marinobacter sp. ELB17].	28.51	670	429	15	1	629	1	661	2e-66	243
rs:WP_024691435	DNA topoisomerase III [Pseudomonas syringae].	27.78	666	423	17	1	629	1	645	3e-66	242
rs:WP_004410753	DNA topoisomerase III [Pseudomonas syringae].	27.61	623	408	14	1	592	1	611	3e-66	242
rs:WP_011829934	DNA topoisomerase III [Methylibium petroleiphilum].	27.23	661	433	18	1	629	1	645	3e-66	242
rs:WP_040468959	DNA topoisomerase III, partial [Eubacterium plexicaudatum].	29.37	606	381	16	105	683	2	587	3e-66	241
tr:M1T6W7_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.29	734	420	26	3	673	23	720	3e-66	246
rs:WP_036165815	DNA topoisomerase III [Lysinibacillus sphaericus].	27.26	708	470	16	3	677	4	699	3e-66	243
rs:WP_014821142	DNA topoisomerase III [Pseudomonas stutzeri].	27.11	616	398	13	1	581	1	600	3e-66	241
tr:Q0SRJ7_CLOPS	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ABG87621.1};	27.46	732	463	22	2	685	3	714	3e-66	243
rs:WP_025477253	DNA topoisomerase [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	3e-66	243
rs:WP_044427899	DNA topoisomerase III [Mannheimia haemolytica].	27.81	640	372	15	1	614	1	576	3e-66	241
rs:WP_037319108	hypothetical protein, partial [Ruminobacter sp. RM87].	29.42	639	383	16	3	581	10	640	3e-66	241
rs:WP_002299737	DNA topoisomerase [Enterococcus faecium].	28.67	715	451	20	3	673	4	703	3e-66	243
rs:WP_024636303	DNA topoisomerase [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	3e-66	243
tr:G9X0K0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.88	484	282	12	1	473	1	457	3e-66	237
rs:WP_002335714	DNA topoisomerase III [Enterococcus faecium].	28.67	715	451	21	3	673	4	703	3e-66	243
rs:WP_002329190	DNA topoisomerase [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	3e-66	243
rs:WP_025477051	DNA topoisomerase [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	3e-66	243
rs:WP_000366824	DNA topoisomerase III [Salmonella enterica].	26.77	747	457	18	1	678	1	726	3e-66	243
rs:WP_024683169	DNA topoisomerase III [Pseudomonas syringae].	27.29	623	410	13	1	592	1	611	3e-66	242
tr:T0NZ48_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.26	542	338	12	3	533	4	516	3e-66	238
rs:WP_034037691	DNA topoisomerase III [Pseudomonas aeruginosa].	27.34	662	431	17	1	629	1	645	3e-66	242
rs:WP_042577333	DNA topoisomerase III [Variovorax paradoxus].	28.36	758	440	26	3	681	4	737	3e-66	246
rs:WP_003423916	DNA topoisomerase III [Pseudomonas syringae].	27.45	623	409	14	1	592	1	611	3e-66	241
rs:WP_041485226	DNA topoisomerase III [beta proteobacterium CB].	29.16	734	421	26	3	673	1	698	3e-66	245
rs:WP_039423446	DNA topoisomerase I [Porphyromonas gulae].	29.14	707	458	20	1	684	1	687	3e-66	242
rs:WP_005744254	DNA topoisomerase III [Pseudomonas amygdali].	27.45	623	409	14	1	592	1	611	3e-66	241
rs:WP_007247388	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	27.84	661	429	16	1	629	1	645	3e-66	242
rs:WP_033795056	DNA topoisomerase [Enterococcus faecium].	27.78	720	451	19	3	667	4	709	3e-66	243
rs:WP_002319742	DNA topoisomerase [Enterococcus faecium].	28.67	715	451	20	3	673	4	703	3e-66	243
tr:D4C6D6_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.43	493	301	14	1	471	1	473	3e-66	238
rs:WP_039314343	DNA topoisomerase [Clostridium baratii].	28.75	720	457	21	2	680	3	707	3e-66	243
rs:WP_047185446	DNA topoisomerase [Bacilli bacterium VT-13-104].	29.56	724	443	28	1	678	1	703	3e-66	243
rs:WP_002320569	DNA topoisomerase [Enterococcus faecium].	27.23	716	451	18	3	667	4	700	3e-66	243
rs:WP_034552912	DNA topoisomerase III [Carnobacterium funditum].	28.21	670	406	20	3	649	4	621	3e-66	242
rs:WP_032614657	DNA topoisomerase III [Pseudomonas syringae].	26.97	623	412	13	1	592	1	611	3e-66	241
rs:WP_037009569	DNA topoisomerase III, partial [Pseudomonas sp. RL].	27.20	614	410	13	1	585	1	606	3e-66	241
rs:WP_038657937	DNA topoisomerase III [Pseudomonas stutzeri].	26.95	616	399	13	1	581	1	600	3e-66	241
rs:WP_002340635	DNA topoisomerase III [Enterococcus faecium].	28.67	715	451	21	3	673	4	703	3e-66	243
gpu:CP011509_1477	DNA topoisomerase III [Archangium gephyra]	27.86	646	392	17	4	590	12	642	3e-66	249
rs:WP_036647111	DNA topoisomerase III [Paenibacillus pini].	27.55	755	458	22	3	683	4	743	4e-66	243
rs:WP_024562713	DNA topoisomerase III, partial [Cronobacter turicensis].	31.09	550	344	15	59	581	11	552	4e-66	240
rs:WP_024692225	DNA topoisomerase III [Pseudomonas syringae].	27.29	623	410	14	1	592	1	611	4e-66	241
rs:WP_013739402	DNA topoisomerase III [Sphaerochaeta coccoides].	29.33	641	403	17	2	615	3	620	4e-66	244
rs:WP_024650185	DNA topoisomerase III [Pseudomonas syringae].	27.84	661	429	16	1	629	1	645	4e-66	242
rs:WP_043526606	DNA topoisomerase III [Halomonas xinjiangensis].	26.76	669	438	17	1	641	1	645	4e-66	241
rs:WP_010732632	DNA topoisomerase III [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	4e-66	243
rs:WP_046811118	topoisomerase I [Lactobacillus plantarum].	29.24	619	398	15	3	592	4	611	4e-66	242
rs:WP_010724052	DNA topoisomerase III [Enterococcus faecium].	28.67	715	451	20	3	673	4	703	4e-66	243
rs:WP_034568898	DNA topoisomerase III [Carnobacterium divergens].	28.66	663	400	21	3	643	4	615	4e-66	242
rs:WP_016839134	DNA topoisomerase [Ureibacillus thermosphaericus].	30.07	725	438	26	1	678	1	703	4e-66	243
tr:S4E644_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.53	715	452	20	3	673	21	720	4e-66	243
rs:WP_012816503	DNA topoisomerase III [Staphylococcus aureus].	29.17	713	448	19	3	680	4	694	4e-66	242
rs:WP_011968211	DNA topoisomerase [Clostridium beijerinckii].	27.69	733	447	21	2	679	3	707	4e-66	243
rs:WP_018914713	DNA topoisomerase III [Thiomonas sp. FB-6].	27.40	719	454	25	3	677	5	699	4e-66	245
rs:WP_042825712	conjugal transfer protein TraE [Xanthomonas axonopodis].	29.20	654	405	18	1	614	1	636	4e-66	243
rs:WP_009511995	DNA topoisomerase III [Opitutaceae bacterium TAV5].	27.86	743	433	26	3	675	4	713	4e-66	245
rs:WP_026885431	DNA topoisomerase [Clostridium beijerinckii].	27.69	733	447	21	2	679	3	707	4e-66	243
rs:WP_031688162	DNA topoisomerase III [Pseudomonas aeruginosa].	27.23	661	433	17	1	629	1	645	5e-66	241
rs:WP_035393414	DNA topoisomerase III, partial [Faecalibacterium prausnitzii].	35.75	414	240	9	1	404	1	398	5e-66	236
rs:WP_042853333	DNA topoisomerase III [Staphylococcus aureus].	29.72	720	435	21	3	680	4	694	5e-66	242
rs:WP_024661949	DNA topoisomerase III [Pseudomonas syringae].	27.29	623	410	15	1	592	1	611	5e-66	241
rs:WP_018412454	DNA topoisomerase III [Methyloversatilis sp. NVD].	27.52	723	453	20	2	676	4	703	5e-66	244
rs:WP_002318768	DNA topoisomerase [Enterococcus faecium].	28.39	715	453	20	3	673	4	703	5e-66	243
rs:WP_024652300	DNA topoisomerase III [Pseudomonas syringae].	27.72	624	406	14	1	592	1	611	5e-66	241
rs:WP_023657732	DNA topoisomerase III [Pseudomonas aeruginosa].	27.53	661	431	18	1	629	1	645	5e-66	241
rs:WP_024633998	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	30.08	615	370	21	3	577	4	598	5e-66	243
rs:WP_004412596	DNA topoisomerase III [Pseudomonas syringae].	27.45	623	409	14	1	592	1	611	5e-66	241
rs:WP_031874414	DNA topoisomerase III [Staphylococcus aureus].	29.17	713	448	19	3	680	4	694	5e-66	242
rs:WP_028102328	DNA topoisomerase III [Pseudoduganella violaceinigra].	28.61	727	443	24	3	680	5	704	5e-66	244
rs:WP_017085213	DNA topoisomerase III [Vibrio splendidus].	28.46	650	423	14	1	614	1	644	5e-66	243
rs:WP_025481902	DNA topoisomerase [Enterococcus faecium].	28.67	715	451	20	3	673	4	703	5e-66	243
rs:WP_042742432	DNA topoisomerase III [Staphylococcus aureus].	29.79	715	441	20	3	680	4	694	5e-66	242
rs:WP_005779714	DNA topoisomerase III [Pseudomonas amygdali].	27.45	623	409	14	1	592	1	611	5e-66	241
rs:WP_043547201	DNA topoisomerase III [Pseudomonas aeruginosa].	27.19	662	432	17	1	629	1	645	5e-66	241
rs:WP_043298804	DNA topoisomerase III [Pseudomonas sp. HMP271].	27.12	612	402	11	1	581	4	602	5e-66	241
tr:C7H1C5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	35.75	414	240	9	1	404	1	398	5e-66	237
rs:WP_034528476	topoisomerase I [Lactobacillus oryzae].	29.61	608	388	15	3	581	4	600	5e-66	242
rs:WP_002338047	DNA topoisomerase III, partial [Enterococcus faecium].	27.52	694	435	17	3	647	4	678	5e-66	241
rs:WP_020616278	hypothetical protein [Paenibacillus daejeonensis].	30.96	617	365	23	3	577	4	601	5e-66	243
rs:WP_020192167	DNA topoisomerase III [Pseudomonas putida].	27.27	660	434	17	1	629	1	645	5e-66	241
rs:WP_010454695	DNA topoisomerase III [Succinivibrionaceae bacterium WG-1].	29.17	617	382	18	3	578	5	607	5e-66	243
rs:WP_039607059	DNA topoisomerase III, partial [Pseudomonas tuomuerensis].	26.55	614	414	12	1	585	1	606	5e-66	240
rs:WP_017245828	DNA topoisomerase III [Pseudomonas stutzeri].	27.11	616	398	13	1	581	1	600	5e-66	241
rs:WP_046270416	DNA topoisomerase III [Pseudomonas syringae].	27.61	623	408	14	1	592	1	611	5e-66	241
rs:WP_028541705	DNA topoisomerase III [Paenibacillus sp. UNCCL52].	29.58	612	376	20	3	577	4	597	6e-66	243
rs:WP_027898417	DNA topoisomerase III [Pseudomonas syringae].	28.06	613	393	15	1	580	1	598	6e-66	241
rs:WP_047234969	DNA topoisomerase III [Aeromonas hydrophila].	27.12	649	422	14	1	610	1	637	6e-66	242
rs:WP_010778097	DNA topoisomerase III [Enterococcus faecium].	28.81	715	450	21	3	673	4	703	6e-66	243
rs:WP_024664267	DNA topoisomerase III [Pseudomonas syringae].	27.29	623	410	13	1	592	1	611	6e-66	241
rs:WP_031864845	DNA topoisomerase III [Staphylococcus aureus].	29.79	715	441	20	3	680	4	694	6e-66	242
tr:A0A081BJM0_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.61	608	388	15	3	581	6	602	6e-66	242
rs:WP_045156433	DNA topoisomerase III [Pseudomonas fluorescens].	27.42	609	398	13	1	578	1	596	6e-66	241
rs:WP_025993493	DNA topoisomerase III [Pseudomonas viridiflava].	27.29	623	410	13	1	592	1	611	6e-66	241
rs:WP_000520734	DNA topoisomerase I [Bacillus cereus].	28.45	710	447	20	3	675	5	690	6e-66	244
rs:WP_018306873	DNA topoisomerase III [Desulfitobacterium hafniense].	26.84	775	441	25	3	676	5	754	6e-66	243
rs:WP_013983541	DNA topoisomerase III [Pseudomonas stutzeri].	26.90	617	398	13	1	581	1	600	6e-66	241
rs:WP_042253463	topoisomerase I [Lactobacillus brevis].	29.61	608	388	15	3	581	4	600	6e-66	242
tr:F3FGU8_PSESX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	28.62	587	377	12	1	557	1	575	6e-66	239
rs:WP_005812716	DNA topoisomerase III [Desulfitobacterium hafniense].	26.84	775	441	25	3	676	5	754	6e-66	243
rs:WP_022297090	DNA topoisomerase III [Clostridium sp. CAG:465].	30.09	638	378	17	2	578	3	633	6e-66	241
tr:F3ET09_PSEA0	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.29	623	410	13	1	592	1	611	6e-66	241
rs:WP_046832659	DNA topoisomerase III [Pseudomonas amygdali].	28.05	663	425	17	1	629	1	645	6e-66	241
rs:WP_020313368	DNA topoisomerase III [Pseudomonas syringae].	28.69	718	455	18	1	673	1	706	6e-66	242
rs:WP_034365963	DNA topoisomerase III [Delftia sp. 670].	26.93	661	435	16	1	629	1	645	6e-66	241
rs:WP_031906444	DNA topoisomerase III [Staphylococcus aureus].	29.17	713	448	19	3	680	4	694	6e-66	242
rs:WP_022777123	DNA topoisomerase [Butyrivibrio sp. AE3009].	26.36	751	475	20	2	679	4	749	6e-66	246
rs:WP_039721732	topoisomerase I [Methylacidiphilum kamchatkense].	31.66	619	355	22	3	574	5	602	6e-66	244
rs:WP_004418049	DNA topoisomerase III [Pseudomonas syringae].	27.45	623	409	14	1	592	1	611	6e-66	241
rs:WP_019405243	DNA topoisomerase III [Pseudomonas stutzeri].	27.11	616	398	13	1	581	1	600	7e-66	240
rs:WP_010436617	DNA topoisomerase III [Pseudomonas syringae].	27.29	623	410	14	1	592	1	611	7e-66	241
rs:WP_045700710	hypothetical protein, partial [Desulfobulbaceae bacterium BRH_c16a].	29.34	668	420	19	1	639	1	645	7e-66	240
rs:WP_002341464	DNA topoisomerase III [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	7e-66	242
rs:WP_008367437	DNA topoisomerase III [Pseudomonas sp. M47T1].	27.20	614	397	13	1	580	1	598	7e-66	240
rs:WP_019335150	DNA topoisomerase III [Pseudomonas syringae].	27.84	668	420	17	1	629	1	645	7e-66	241
tr:B4D958_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.98	654	413	17	3	618	4	637	7e-66	240
rs:WP_009616856	DNA topoisomerase III [Desulfosporosinus sp. OT].	28.40	771	442	23	3	676	5	762	7e-66	243
rs:WP_002335043	DNA topoisomerase III [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	7e-66	242
rs:WP_013172858	DNA topoisomerase III [[Bacillus] selenitireducens].	27.63	731	467	21	1	683	1	717	7e-66	242
rs:WP_031864418	DNA topoisomerase III [Staphylococcus aureus].	29.17	713	448	19	3	680	4	694	7e-66	241
rs:WP_043305647	DNA topoisomerase III [Pseudomonas viridiflava].	27.40	624	408	13	1	592	1	611	8e-66	241
rs:WP_016172934	DNA topoisomerase III [Enterococcus dispar].	28.36	663	406	18	2	644	4	617	8e-66	241
rs:WP_037352392	DNA topoisomerase [Selenomonas sp. FC4001].	27.74	674	434	16	2	640	4	659	8e-66	242
rs:WP_009672956	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	31.43	595	371	18	4	580	6	581	8e-66	239
rs:WP_044321692	DNA topoisomerase III [Pseudomonas amygdali].	27.45	623	409	13	1	592	1	611	8e-66	240
rs:WP_002333268	MULTISPECIES: DNA topoisomerase [Enterococcus].	28.53	715	452	20	3	673	4	703	8e-66	242
rs:WP_011633516	DNA topoisomerase III [Nitrosomonas eutropha].	28.20	727	435	25	2	675	4	696	8e-66	243
rs:WP_042335867	DNA topoisomerase III [Candidatus Accumulibacter sp. BA-92].	27.96	744	426	30	2	676	4	706	8e-66	244
rs:WP_028241262	DNA topoisomerase III [Pseudomonas azotifigens].	27.33	611	402	11	1	581	1	599	8e-66	240
rs:WP_016567955	DNA topoisomerase III [Pseudomonas syringae].	27.13	623	411	14	1	592	1	611	8e-66	240
tr:A0A0A1GLH5_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.14	608	402	12	1	578	2	598	9e-66	240
rs:WP_002327915	DNA topoisomerase III [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	9e-66	242
rs:WP_045429170	DNA topoisomerase III [Pseudomonas sp. MT-1].	27.14	608	402	12	1	578	1	597	9e-66	240
rs:WP_008540190	DNA topoisomerase III [Megamonas funiformis].	28.46	671	428	19	1	642	1	648	9e-66	241
rs:WP_029593788	DNA topoisomerase [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	9e-66	242
rs:WP_002345924	DNA topoisomerase III [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	9e-66	242
rs:WP_044308340	DNA topoisomerase III [Pseudomonas syringae].	27.13	623	411	15	1	592	1	611	9e-66	240
rs:WP_036665367	DNA topoisomerase III [Paenibacillus sp. FSL H8-457].	27.53	752	448	25	3	673	4	739	9e-66	242
rs:WP_022076992	DNA topoisomerase III [Clostridium sp. CAG:571].	31.56	640	366	21	2	579	4	633	9e-66	240
rs:WP_010727770	DNA topoisomerase III [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	9e-66	242
rs:WP_002340047	DNA topoisomerase III [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	9e-66	242
rs:WP_002376837	DNA topoisomerase [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	1e-65	242
rs:WP_027640143	DNA topoisomerase [Clostridium cadaveris].	28.41	725	451	23	2	679	3	706	1e-65	241
rs:WP_043902498	DNA topoisomerase [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	1e-65	242
rs:WP_002337695	DNA topoisomerase III [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	1e-65	242
rs:WP_027415690	DNA topoisomerase [Aneurinibacillus terranovensis].	29.58	720	448	25	1	678	1	703	1e-65	241
tr:W2BXL6_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.67	496	289	13	3	486	4	471	1e-65	239
rs:WP_014827249	DNA topoisomerase III [Desulfosporosinus acidiphilus].	27.11	760	457	22	2	678	4	749	1e-65	242
rs:WP_042926554	DNA topoisomerase III [Pseudomonas chloritidismutans].	26.95	616	399	13	1	581	1	600	1e-65	240
rs:WP_032517984	DNA topoisomerase, partial [Peptoclostridium difficile].	29.20	654	402	17	68	675	3	641	1e-65	240
rs:WP_014386915	DNA topoisomerase [Pediococcus claussenii].	29.53	623	391	17	3	592	4	611	1e-65	241
rs:WP_046331014	DNA topoisomerase III [Polynucleobacter necessarius].	28.57	728	433	23	3	673	23	720	1e-65	244
rs:WP_038574535	DNA topoisomerase III [Paenibacillus odorifer].	26.96	753	449	24	3	673	4	737	1e-65	242
tr:M7NHP8_9BACT	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EMR01315.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EMR01315.1};	28.79	653	392	16	85	678	3	641	1e-65	240
rs:WP_019375117	DNA topoisomerase III [Alicycliphilus sp. CRZ1].	28.21	677	401	22	3	611	5	664	1e-65	244
rs:WP_031902829	DNA topoisomerase III [Staphylococcus aureus].	29.65	715	442	20	3	680	4	694	1e-65	241
rs:WP_035779454	DNA topoisomerase III, partial [Clostridium butyricum].	33.49	433	255	9	1	415	1	418	1e-65	236
rs:WP_002327040	DNA topoisomerase III [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	1e-65	242
rs:WP_025477629	DNA topoisomerase [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	1e-65	242
rs:WP_043320923	ATP-dependent DNA helicase RecQ [Corallococcus coralloides].	26.79	642	399	15	4	581	32	666	1e-65	248
rs:WP_041013371	DNA topoisomerase III [Pseudomonas xanthomarina].	27.58	689	434	19	1	646	1	667	1e-65	241
rs:WP_023011009	DNA topoisomerase III [Marinobacter sp. EN3].	28.88	651	411	18	1	614	1	636	1e-65	241
rs:WP_002322737	DNA topoisomerase [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	1e-65	242
rs:WP_002422089	DNA topoisomerase III, partial [Yersinia pestis].	30.86	538	321	20	1	502	1	523	1e-65	237
rs:WP_032548386	DNA topoisomerase, partial [Peptoclostridium difficile].	29.19	644	403	16	68	673	3	631	1e-65	239
rs:WP_045470857	DNA topoisomerase III [Burkholderiales bacterium GJ-E10].	27.70	740	436	23	3	673	6	715	1e-65	243
tr:H8N181_CORCM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.79	642	399	15	4	581	37	671	1e-65	248
rs:WP_002345093	DNA topoisomerase III [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	1e-65	242
rs:WP_004665587	DNA topoisomerase III [Pseudomonas savastanoi].	27.45	623	409	14	1	592	1	611	1e-65	240
rs:WP_011793734	DNA topoisomerase III [Acidovorax citrulli].	27.53	672	425	19	1	629	1	653	1e-65	241
rs:WP_016264956	DNA topoisomerase III [Lactobacillus sakei].	29.84	620	384	15	2	610	4	583	1e-65	241
rs:WP_042188790	DNA topoisomerase III [Paenibacillus sp. FSL H7-0737].	26.83	753	450	24	3	673	4	737	1e-65	242
rs:WP_015734703	DNA topoisomerase III [Paenibacillus sp. Y412MC10].	27.53	752	448	25	3	673	4	739	1e-65	242
rs:WP_013721964	DNA topoisomerase III [Alicycliphilus denitrificans].	26.47	646	423	15	1	614	1	626	1e-65	240
rs:WP_044039552	DNA topoisomerase III [Clostridium sp. M2/40].	28.36	737	454	22	3	673	5	733	1e-65	241
rs:WP_031897507	DNA topoisomerase III, partial [Staphylococcus aureus].	32.73	550	326	15	86	615	1	526	1e-65	239
rs:WP_031867296	DNA topoisomerase III [Staphylococcus aureus].	30.14	720	432	22	3	680	4	694	1e-65	241
rs:WP_044145021	DNA topoisomerase [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	1e-65	241
rs:WP_021206679	DNA topoisomerase III [Pseudomonas stutzeri].	27.41	613	394	16	1	578	1	597	1e-65	239
rs:WP_023093157	hypothetical protein [Pseudomonas aeruginosa].	27.34	662	431	18	1	629	1	645	1e-65	240
rs:WP_024960796	DNA topoisomerase III [Pseudomonas syringae].	28.16	664	423	17	1	629	1	645	1e-65	240
rs:WP_013041960	DNA topoisomerase III [Coraliomargarita akajimensis].	28.18	738	444	25	3	682	4	713	1e-65	243
rs:WP_028585602	DNA topoisomerase III [Desulfobulbus mediterraneus].	29.87	703	413	26	3	657	5	675	1e-65	243
tr:F3GYQ3_PSESX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.13	623	411	14	1	592	1	611	1e-65	242
tr:R0AE94_CLOBU	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	33.49	433	255	9	1	415	1	418	1e-65	236
rs:WP_039299128	DNA topoisomerase III [Paenibacillus sp. IHB B 3415].	27.63	760	440	29	3	673	4	742	1e-65	241
rs:WP_035508200	MULTISPECIES: DNA topoisomerase III [Halobacillus].	28.15	714	418	19	3	658	4	680	1e-65	241
rs:WP_035230495	DNA topoisomerase III [Desulfobulbus sp. Tol-SR].	29.20	702	419	24	3	657	6	676	1e-65	243
rs:WP_035129939	DNA topoisomerase [Clostridium sulfidigenes].	28.57	742	445	24	2	680	3	722	1e-65	241
tr:J8ZXU3_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.53	715	452	20	3	673	21	720	1e-65	242
rs:WP_047275872	DNA topoisomerase III [Pseudomonas fluorescens].	27.66	611	394	12	1	578	1	596	1e-65	239
rs:WP_028597698	DNA topoisomerase III [Paenibacillus pasadenensis].	29.95	611	384	18	3	581	4	602	1e-65	242
rs:WP_041397274	DNA topoisomerase III [Polynucleobacter necessarius].	28.45	724	437	22	4	673	1	697	1e-65	243
rs:WP_033493981	DNA topoisomerase III [Bifidobacterium thermophilum].	26.07	748	462	22	1	683	1	722	1e-65	241
rs:WP_028403521	DNA topoisomerase III [Bacillus sp. J13].	26.90	751	453	24	3	673	4	738	2e-65	241
rs:WP_046668838	DNA topoisomerase, partial [Enterococcus faecium].	27.87	671	427	16	41	667	7	664	2e-65	240
rs:WP_025163529	DNA topoisomerase III [Pseudomonas taeanensis].	27.18	607	402	11	1	578	1	596	2e-65	239
rs:WP_044384737	DNA topoisomerase III [Marinobacter excellens].	29.14	652	418	16	1	615	1	645	2e-65	241
rs:WP_015474608	DNA topoisomerase III [Lactobacillus brevis].	29.28	608	390	16	3	581	4	600	2e-65	241
rs:WP_047276194	DNA topoisomerase III [Pseudomonas fluorescens].	27.66	611	394	12	1	578	1	596	2e-65	239
tr:U5JDV2_PEPDI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.20	654	402	17	68	675	1	639	2e-65	239
rs:WP_031925419	DNA topoisomerase III [Staphylococcus aureus].	29.03	713	449	19	3	680	4	694	2e-65	241
rs:WP_041142936	topoisomerase I [Lactobacillus plantarum].	29.41	612	384	16	3	581	4	600	2e-65	241
rs:WP_015474661	DNA topoisomerase III [Lactobacillus brevis].	29.24	619	398	15	3	592	4	611	2e-65	241
rs:WP_039107789	topoisomerase I [Lactobacillus brevis].	28.55	620	401	15	3	592	4	611	2e-65	241
rs:WP_047280872	DNA topoisomerase III [Pseudomonas fluorescens].	27.66	611	394	12	1	578	1	596	2e-65	239
rs:WP_036666677	DNA topoisomerase III, partial [Paenibacillus darwinianus].	31.12	617	365	21	3	577	4	602	2e-65	239
rs:WP_043220266	DNA topoisomerase III [Pseudomonas balearica].	27.11	616	397	14	1	581	1	599	2e-65	239
rs:WP_042732096	DNA topoisomerase III [Pseudomonas fluorescens].	27.63	608	398	14	1	578	1	596	2e-65	239
rs:WP_005732953	DNA topoisomerase III [Pseudomonas amygdali].	27.56	624	407	14	1	592	1	611	2e-65	239
rs:WP_036716163	DNA topoisomerase III, partial [Paenibacillus darwinianus].	31.12	617	365	21	3	577	4	602	2e-65	239
rs:WP_036579540	DNA topoisomerase III, partial [Paenibacillus darwinianus].	31.12	617	365	21	3	577	4	602	2e-65	239
rs:WP_010188183	conjugal transfer protein TraE [Sphingomonas sp. PAMC 26605].	27.67	665	424	16	3	629	6	651	2e-65	241
tr:A0A060M1P7_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.75	717	472	19	3	682	4	711	2e-65	241
tr:S4F4D5_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.53	715	452	20	3	673	63	762	2e-65	242
rs:WP_022992872	DNA topoisomerase III [Marinobacter sp. C1S70].	29.21	647	414	15	1	614	1	636	2e-65	241
rs:WP_006858739	DNA topoisomerase [Roseburia intestinalis].	26.30	749	473	19	3	679	5	746	2e-65	246
rs:WP_007360327	DNA topoisomerase III [Opitutaceae bacterium TAV1].	28.04	749	427	28	3	675	4	716	2e-65	243
rs:WP_015944491	DNA topoisomerase III [Desulfitobacterium hafniense].	26.99	778	439	26	3	676	5	757	2e-65	241
gpu:CP011020_4882	DNA topoisomerase III [Pseudomonas chlororaphis]	27.63	608	398	14	1	578	1	596	2e-65	239
rs:WP_013544274	DNA topoisomerase III [Variovorax paradoxus].	28.06	759	441	26	3	681	5	738	2e-65	243
rs:WP_047282777	DNA topoisomerase III [Pseudomonas fluorescens].	27.66	611	394	12	1	578	1	596	2e-65	239
rs:WP_036687820	DNA topoisomerase III [Paenibacillus sp. FSL H8-237].	26.69	753	451	23	3	673	4	737	2e-65	241
rs:WP_022792534	DNA topoisomerase III [Marinococcus halotolerans].	29.72	710	435	28	1	664	1	692	2e-65	241
tr:W4BTV7_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.69	753	451	23	3	673	6	739	2e-65	241
rs:WP_036142091	DNA topoisomerase III [Lysinibacillus sp. BF-4].	29.27	714	438	25	3	673	4	693	2e-65	240
rs:WP_036994754	DNA topoisomerase III [Pseudomonas sp. P482].	27.30	608	400	13	1	578	1	596	2e-65	239
rs:WP_034893651	DNA topoisomerase III, partial [Candidatus Accumulibacter sp. SK-11].	30.32	630	372	21	2	581	4	616	2e-65	239
rs:WP_045861762	hypothetical protein [Alteromonadaceae bacterium Bs12].	28.94	615	395	12	1	579	1	609	2e-65	241
rs:WP_038486162	DNA topoisomerase III, partial [Bacillus lehensis].	27.82	701	467	18	3	673	4	695	2e-65	240
rs:WP_033612972	DNA topoisomerase, partial [Enterococcus faecium].	30.17	653	393	19	3	611	4	637	2e-65	239
rs:WP_039433724	DNA topoisomerase I [Porphyromonas gulae].	29.29	717	444	22	1	684	1	687	2e-65	240
rs:WP_002328427	DNA topoisomerase III [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	2e-65	241
rs:WP_035170845	hypothetical protein [Campylobacter fetus].	29.40	687	413	20	1	640	1	662	2e-65	239
rs:WP_029243501	DNA topoisomerase III [Pseudomonas viridiflava].	26.97	623	412	13	1	592	1	611	2e-65	239
rs:WP_031919412	DNA topoisomerase III [Staphylococcus aureus].	29.97	684	419	19	3	650	4	663	2e-65	240
rs:WP_002296700	DNA topoisomerase [Enterococcus faecium].	28.53	715	452	20	3	673	63	762	2e-65	242
tr:A0A098EYV3_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.38	725	447	25	2	681	3	707	2e-65	240
rs:WP_045352997	topoisomerase I [Lactobacillus plantarum].	29.08	619	399	15	3	592	4	611	2e-65	240
rs:WP_000542405	topoisomerase III [Bacillus cereus].	30.45	716	436	23	3	676	5	700	2e-65	240
rs:WP_047294473	DNA topoisomerase III [Pseudomonas fluorescens].	27.66	611	394	12	1	578	1	596	3e-65	239
rs:WP_046152240	DNA topoisomerase III [Burkholderia andropogonis].	28.15	714	443	22	3	673	5	691	3e-65	243
rs:WP_024903475	DNA topoisomerase III [Burkholderia andropogonis].	28.15	714	443	22	3	673	5	691	3e-65	243
rs:WP_012816538	DNA topoisomerase III [Staphylococcus aureus].	29.97	684	419	19	3	650	4	663	3e-65	240
rs:WP_009401127	DNA topoisomerase III [Pseudomonas putida].	27.12	660	435	17	1	629	1	645	3e-65	239
tr:A0A096H590_LACPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.93	608	386	16	3	581	4	600	3e-65	240
rs:WP_014597325	DNA topoisomerase III [Pseudomonas stutzeri].	27.33	611	403	13	1	581	1	600	3e-65	239
rs:WP_039282953	DNA topoisomerase III [Clostridium botulinum].	28.34	748	446	24	3	673	5	739	3e-65	241
rs:WP_022476560	DNA topoisomerase [Clostridium sp. CAG:273].	29.20	654	379	17	3	579	38	684	3e-65	239
rs:WP_010014514	DNA topoisomerase III [Lactobacillus coryniformis].	29.44	608	389	15	3	581	4	600	3e-65	240
rs:WP_046041317	topoisomerase I [Lactobacillus plantarum].	29.61	608	388	16	3	581	4	600	3e-65	240
rs:WP_002343287	DNA topoisomerase III [Enterococcus faecium].	28.53	715	452	20	3	673	4	703	3e-65	241
rs:WP_000520729	DNA topoisomerase I [Bacillus cereus].	28.31	710	448	20	3	675	5	690	3e-65	243
rs:WP_040262903	DNA topoisomerase III [Pseudomonas sp. CB1].	26.05	645	402	14	1	581	1	634	3e-65	239
rs:WP_022182875	DNA topoisomerase [Clostridium sp. CAG:575].	30.02	663	372	19	2	579	4	659	3e-65	239
rs:WP_019533739	DNA topoisomerase III [Paenibacillus ginsengihumi].	29.64	631	394	20	3	597	4	620	3e-65	241
tr:A0A0C2D1G0_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.09	667	388	22	3	612	4	642	3e-65	246
rs:WP_044344117	DNA topoisomerase III [Pseudomonas meliae].	27.29	623	410	15	1	592	1	611	3e-65	239
rs:WP_042206965	DNA topoisomerase III [Paenibacillus durus].	30.86	619	359	22	3	577	4	597	3e-65	242
rs:WP_046041454	topoisomerase I [Lactobacillus plantarum].	29.40	721	456	19	3	681	4	713	3e-65	240
rs:WP_013721070	DNA topoisomerase III [Lactobacillus buchneri].	29.67	610	385	16	3	581	4	600	3e-65	240
rs:WP_010729522	DNA topoisomerase III [Enterococcus faecium].	27.55	686	426	19	3	639	4	667	3e-65	239
rs:WP_011785988	DNA topoisomerase III [Marinobacter hydrocarbonoclasticus].	28.79	646	418	14	1	614	1	636	3e-65	240
rs:WP_016526652	DNA topoisomerase [Lactobacillus plantarum].	29.07	719	461	19	3	681	4	713	3e-65	240
rs:WP_012806869	DNA topoisomerase III [Candidatus Accumulibacter phosphatis].	27.09	731	449	23	2	676	4	706	3e-65	242
rs:WP_028604968	DNA topoisomerase III [Ottowia thiooxydans].	27.73	761	434	25	3	666	4	745	3e-65	243
rs:WP_010728361	DNA topoisomerase III [Enterococcus faecium].	28.39	715	453	20	3	673	4	703	3e-65	240
rs:WP_010729361	DNA topoisomerase III [Enterococcus faecium].	27.61	681	432	18	3	639	4	667	3e-65	239
rs:WP_044879959	DNA topoisomerase III [Paenibacillus sp. IHBB 10380].	28.59	717	418	24	3	643	4	702	3e-65	240
rs:WP_046360976	hypothetical protein, partial [Hafnia alvei].	27.79	619	403	16	41	629	31	635	3e-65	238
rs:WP_000520730	DNA topoisomerase I [Bacillus thuringiensis].	28.31	710	448	20	3	675	5	690	3e-65	242
rs:WP_024537139	DNA topoisomerase III [Comamonas badia].	26.97	660	436	17	1	629	1	645	3e-65	239
rs:WP_003561259	DNA topoisomerase III [Lactobacillus buchneri].	29.11	608	391	14	3	581	4	600	3e-65	240
rs:WP_003300857	DNA topoisomerase III [Pseudomonas stutzeri].	26.95	616	399	13	1	581	1	600	3e-65	238
rs:WP_011677354	DNA topoisomerase [Oenococcus oeni].	28.55	697	457	17	3	667	4	691	3e-65	240
rs:WP_035288127	DNA topoisomerase III [Clostridium sp. KNHs214].	28.72	752	445	25	3	673	5	746	4e-65	241
tr:W4V0T6_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.27	550	340	13	1	528	1	534	4e-65	236
tr:W4UM81_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.29	654	424	15	54	683	4	636	4e-65	238
rs:WP_036613668	DNA topoisomerase III [Paenibacillus sp. FSL H7-689].	29.98	617	370	21	3	577	4	600	4e-65	241
rs:WP_042214434	DNA topoisomerase III [Paenibacillus borealis].	27.14	759	445	28	3	673	4	742	4e-65	240
rs:WP_004336217	DNA topoisomerase III [Thauera linaloolentis].	28.83	718	437	24	2	670	4	696	4e-65	242
rs:WP_023444430	DNA topoisomerase III [Pseudomonas chloritidismutans].	26.95	616	399	13	1	581	1	600	4e-65	238
rs:WP_021996258	DNA topoisomerase [Clostridium sp. CAG:780].	29.13	642	385	16	3	579	5	641	4e-65	238
rs:WP_021147943	DNA topoisomerase III [Veillonella parvula].	30.03	606	370	16	1	557	1	601	4e-65	241
rs:WP_026701296	hypothetical protein [Bacillus aidingensis].	28.63	723	449	25	1	678	2	702	4e-65	240
rs:WP_019004931	hypothetical protein [Cohnella laeviribosi].	28.53	673	401	21	3	618	4	653	4e-65	242
rs:WP_046532154	DNA topoisomerase III, partial [Candidatus Accumulibacter phosphatis].	27.48	735	441	27	2	676	4	706	4e-65	242
rs:WP_008639302	MULTISPECIES: DNA topoisomerase III [Bacillaceae].	27.63	684	457	14	3	658	5	678	4e-65	239
rs:WP_014421986	DNA topoisomerase III [Marinobacter hydrocarbonoclasticus].	29.06	647	415	16	1	614	1	636	4e-65	240
tr:W4PNB6_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.48	648	411	19	54	676	2	628	4e-65	238
rs:WP_036673825	DNA topoisomerase III [Paenibacillus sp. FSL R5-192].	29.98	617	370	21	3	577	4	600	4e-65	241
rs:WP_021885775	DNA topoisomerase [Clostridium sp. CAG:590].	30.10	598	386	14	100	683	9	588	4e-65	237
rs:WP_045994243	DNA topoisomerase III [Halomonas sp. S2151].	28.02	646	415	19	1	619	1	623	4e-65	238
rs:WP_013721848	DNA topoisomerase III [Alicycliphilus denitrificans].	26.67	660	438	17	1	629	1	645	4e-65	239
rs:WP_044319251	DNA topoisomerase III [Pseudomonas amygdali].	27.45	623	409	14	1	592	1	611	4e-65	238
rs:WP_035029208	DNA topoisomerase III [Carnobacterium mobile].	27.92	677	417	19	3	655	4	633	4e-65	239
rs:WP_039804356	DNA topoisomerase III [Azotobacter chroococcum].	27.04	614	400	12	1	581	4	602	4e-65	238
rs:WP_019742482	DNA topoisomerase III [Pseudomonas savastanoi].	27.29	623	410	14	1	592	1	611	4e-65	238
rs:WP_005387096	hypothetical protein [Veillonella dispar].	27.94	680	417	17	1	612	1	675	4e-65	240
rs:WP_029699126	DNA topoisomerase III [Clostridium sp. Ade.TY].	29.64	641	385	15	3	588	5	634	4e-65	238
rs:WP_027597366	DNA topoisomerase III [Pseudomonas sp. MOIL14HWK12:I2].	27.00	626	408	15	1	592	1	611	4e-65	238
rs:WP_044159254	DNA topoisomerase I [Bacteroides reticulotermitis].	28.44	640	414	14	68	683	2	621	4e-65	238
rs:WP_041637066	DNA topoisomerase III, partial [Acidithiobacillus caldus].	29.98	567	357	14	36	570	13	571	4e-65	237
rs:WP_029285251	DNA topoisomerase I [Pedobacter sp. R20-19].	27.96	608	398	15	1	582	1	594	5e-65	238
rs:WP_026823973	DNA topoisomerase III [Arsenophonus nasoniae].	28.33	713	453	16	1	673	1	695	5e-65	239
rs:WP_032427309	DNA topoisomerase III, partial [Klebsiella pneumoniae].	33.46	511	305	16	100	581	3	507	5e-65	236
rs:WP_041105535	DNA topoisomerase III [Pseudomonas stutzeri].	26.95	616	398	14	1	581	1	599	5e-65	238
rs:WP_021349356	DNA topoisomerase III [Lactobacillus fermentum].	29.61	608	388	16	3	581	4	600	5e-65	239
rs:WP_034552094	DNA topoisomerase III [Carnobacterium funditum].	28.27	704	460	16	1	673	3	692	5e-65	239
tr:S2SI22_LACPA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.74	612	382	16	3	581	4	600	5e-65	239
rs:WP_039098910	topoisomerase I [Lactobacillus curvatus].	28.95	608	392	14	3	581	4	600	5e-65	239
rs:WP_043902904	DNA topoisomerase [Enterococcus faecium].	28.39	715	453	20	3	673	4	703	5e-65	240
rs:WP_035333217	hypothetical protein [Bacillus firmus].	28.71	707	455	23	3	680	5	691	5e-65	239
rs:WP_029054036	DNA topoisomerase III [Sporosarcina ureae].	28.85	721	443	24	3	675	4	702	5e-65	239
rs:WP_012621109	DNA topoisomerase III [Lactobacillus gasseri].	29.41	612	384	16	3	581	5	601	5e-65	239
rs:WP_005429239	DNA topoisomerase III [Sutterella wadsworthensis].	27.69	733	440	25	3	680	5	702	5e-65	241
rs:WP_009226172	DNA topoisomerase III [Paenibacillus sp. oral taxon 786].	26.48	725	438	19	3	647	4	713	5e-65	240
rs:WP_042134694	DNA topoisomerase III [Pseudomonas oryzihabitans].	27.33	611	396	14	1	578	1	596	6e-65	238
rs:WP_029799342	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	30.45	555	347	14	2	524	3	550	6e-65	236
tr:V1FMZ2_SALCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.39	667	427	18	3	640	6	657	6e-65	238
rs:WP_009168861	DNA topoisomerase [Clostridium sp. DL-VIII].	27.97	733	445	22	2	679	3	707	6e-65	239
rs:WP_003454892	DNA topoisomerase III [Pseudomonas aeruginosa].	27.17	681	438	21	1	641	1	663	6e-65	238
rs:WP_004886535	DNA topoisomerase III [Pseudomonas viridiflava].	27.24	624	409	13	1	592	1	611	6e-65	238
rs:WP_007971786	DNA topoisomerase III [Pseudomonas sp. GM33].	26.95	627	407	15	1	592	4	614	6e-65	238
rs:WP_039972488	DNA topoisomerase I [Bacteroides pyogenes].	29.68	711	435	23	1	677	1	680	6e-65	239
tr:H1PME7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.26	487	281	12	1	473	41	497	6e-65	234
rs:WP_010223989	DNA topoisomerase III [Pseudomonas sp. HYS].	27.30	608	400	13	1	578	1	596	6e-65	238
rs:WP_000063790	DNA topoisomerase [Bacillus cereus].	28.07	709	468	16	3	676	5	706	6e-65	239
rs:WP_025015836	DNA topoisomerase III [Lactobacillus sakei].	29.13	618	391	13	2	610	4	583	6e-65	239
rs:WP_002344214	DNA topoisomerase III [Enterococcus faecium].	28.39	715	453	20	3	673	4	703	6e-65	239
rs:WP_012766322	MULTISPECIES: DNA topoisomerase 3 (DNA topoisomerase III) [Gammaproteobacteria].	26.51	747	459	18	1	678	1	726	6e-65	239
rs:WP_033017430	DNA topoisomerase III [Geobacillus stearothermophilus].	30.91	634	407	16	71	679	1	628	6e-65	238
rs:WP_017430535	DNA topoisomerase III [Halomonas jeotgali].	28.24	602	400	13	1	581	1	591	6e-65	238
rs:WP_044342514	DNA topoisomerase III [Pseudomonas oryzihabitans].	27.33	611	396	14	1	578	1	596	6e-65	238
rs:WP_040536140	hypothetical protein, partial [Legionella drancourtii].	28.23	634	408	18	41	640	3	623	6e-65	237
rs:WP_034017287	DNA topoisomerase III [Pseudomonas aeruginosa].	27.38	661	431	18	1	629	1	644	7e-65	238
rs:WP_023958691	DNA topoisomerase III [Paenibacillus sp. JCM 10914].	27.38	745	447	23	3	673	4	728	7e-65	239
rs:WP_039416653	DNA topoisomerase I [Porphyromonas gingivalis].	29.40	721	438	24	1	684	1	687	7e-65	239
rs:WP_029850627	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	30.45	555	347	14	2	524	3	550	7e-65	235
rs:WP_033698227	DNA topoisomerase I [Bacillus thuringiensis].	28.41	711	446	22	3	675	5	690	7e-65	241
rs:WP_014853514	DNA topoisomerase III [Pseudomonas stutzeri].	27.14	608	401	12	1	578	1	596	7e-65	238
rs:WP_016308801	DNA topoisomerase III [Enterorhabdus caecimuris].	25.31	715	488	15	1	681	1	703	7e-65	239
rs:WP_015062325	DNA topoisomerase III [Salmonella sp. 40].	29.39	667	427	18	3	640	6	657	7e-65	238
rs:WP_014448815	DNA topoisomerase III [Leptospirillum ferrooxidans].	27.38	661	423	15	1	614	1	651	7e-65	240
rs:WP_017794555	hypothetical protein [Streptococcus iniae].	30.59	729	415	24	3	673	4	699	7e-65	239
rs:WP_045196653	DNA topoisomerase III [Pseudomonas sp. 2(2015)].	27.18	607	402	12	1	578	1	596	7e-65	238
rs:WP_045161316	DNA topoisomerase III [Pseudomonas stutzeri].	26.72	610	403	13	1	578	1	598	7e-65	238
rs:WP_011189858	DNA topoisomerase III [Desulfotalea psychrophila].	29.19	716	402	24	3	657	6	677	7e-65	241
tr:F6IUN4_LACPE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.44	608	389	15	3	581	5	601	7e-65	239
rs:WP_016381855	DNA topoisomerase III [Lactobacillus paracasei].	28.76	619	401	14	3	592	4	611	8e-65	239
rs:WP_032822570	topoisomerase I [Oenococcus oeni].	28.41	697	458	17	3	667	4	691	8e-65	239
rs:WP_042749367	topoisomerase I [Lactobacillus brevis].	29.28	608	390	15	3	581	4	600	8e-65	239
rs:WP_022960734	DNA topoisomerase III [Pseudomonas pelagia].	28.26	637	416	17	1	611	1	622	8e-65	238
rs:WP_039310032	DNA topoisomerase III, partial [Clostridium botulinum].	33.09	541	331	14	108	627	3	533	8e-65	237
rs:WP_020207144	DNA topoisomerase III, partial [Cupriavidus sp. WS].	28.57	588	386	13	1	562	1	580	8e-65	236
rs:WP_045158624	DNA topoisomerase III [Pseudomonas stutzeri].	27.33	611	403	13	1	581	1	600	8e-65	238
rs:WP_020308035	DNA topoisomerase III [Pseudomonas stutzeri].	26.97	660	436	17	1	629	1	645	8e-65	238
rs:WP_021994635	DNA topoisomerase [Sutterella wadsworthensis CAG:135].	27.83	733	439	25	3	680	5	702	8e-65	241
rs:WP_039272426	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	26.51	747	459	18	1	678	1	726	8e-65	239
tr:A0A087FB29_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.12	660	428	18	1	629	1	638	8e-65	238
tr:C9LYN3_SELS3	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.13	647	406	20	30	630	16	649	8e-65	239
rs:WP_039873735	DNA topoisomerase III [Paenibacillus sp. FSL R7-0273].	30.97	620	365	23	3	581	4	601	8e-65	239
rs:WP_005730106	DNA topoisomerase III [Pseudomonas amygdali].	27.15	663	431	16	1	629	1	645	8e-65	238
rs:WP_036131029	DNA topoisomerase III [Marinobacter sp. AK21].	29.08	650	411	18	1	614	1	636	8e-65	239
rs:WP_041224587	DNA topoisomerase III, partial [Dechloromonas aromatica].	27.29	733	445	23	2	676	4	706	8e-65	240
rs:WP_039106709	topoisomerase I [Lactobacillus brevis].	29.28	608	390	15	3	581	4	600	9e-65	239
rs:WP_043743360	DNA topoisomerase III [Thauera sp. SWB20].	26.82	660	437	17	1	629	1	645	9e-65	238
rs:WP_036638054	DNA topoisomerase III [Paenibacillus sp. FSL R5-808].	29.25	612	380	20	3	577	4	599	9e-65	239
rs:WP_044393699	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	28.01	664	424	17	1	629	1	645	9e-65	238
tr:A0A091BZB1_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.36	579	368	13	41	611	3	548	9e-65	238
tr:E6QBD0_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CBI04506.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI04506.1};	30.10	618	376	18	3	581	4	604	9e-65	237
rs:WP_010829678	DNA topoisomerase III [Enterococcus faecium].	28.45	710	459	19	3	673	4	703	9e-65	239
rs:WP_044822506	DNA topoisomerase III [Bacillus thuringiensis].	27.73	732	453	19	3	676	7	720	9e-65	240
rs:WP_019554952	DNA topoisomerase III [Propionispira raffinosivorans].	26.47	680	432	19	5	642	7	660	1e-64	238
tr:D4J464_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.52	647	400	17	3	626	4	617	1e-64	238
tr:W1W148_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.22	643	421	13	3	621	4	623	1e-64	238
rs:WP_031271200	DNA topoisomerase III, partial [Lachnospiraceae bacterium 10-1].	30.05	619	374	18	105	682	3	603	1e-64	236
rs:WP_008427758	topoisomerase IA [Clostridium sp. Maddingley MBC34-26].	28.42	732	441	23	2	678	3	706	1e-64	239
rs:WP_020306940	DNA topoisomerase III [Pseudomonas stutzeri].	27.17	611	404	13	1	581	1	600	1e-64	237
tr:W1W322_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.94	680	417	17	1	612	1	675	1e-64	239
rs:WP_024673600	DNA topoisomerase III [Pseudomonas syringae].	27.27	616	405	13	1	585	1	604	1e-64	237
rs:WP_009667728	DNA topoisomerase III [Oxalobacteraceae bacterium IMCC9480].	28.75	727	441	24	3	680	5	703	1e-64	241
tr:A0NKA9_OENOE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.41	697	458	17	3	667	11	698	1e-64	239
rs:WP_024962447	DNA topoisomerase III [Campylobacter ureolyticus].	30.13	687	410	22	1	640	1	664	1e-64	238
rs:WP_017415987	hypothetical protein [Clostridium tunisiense].	28.88	748	438	24	3	673	5	735	1e-64	239
rs:WP_034230048	DNA topoisomerase, partial [Lachnobacterium bovis].	26.40	750	468	21	3	675	5	747	1e-64	239
rs:WP_006209708	DNA topoisomerase III [Paenibacillus vortex].	29.25	612	380	20	3	577	4	599	1e-64	239
rs:WP_003590797	DNA topoisomerase III [Lactobacillus casei].	29.61	608	388	16	3	581	4	600	1e-64	238
tr:Q47K54_DECAR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.29	733	445	23	2	676	13	715	1e-64	240
rs:WP_013744085	DNA topoisomerase III [Pusillimonas sp. T7-7].	28.57	728	430	23	3	675	5	697	1e-64	241
rs:WP_037023194	DNA topoisomerase III [Pseudomonas sp. 20_BN].	26.59	613	402	11	1	580	1	598	1e-64	237
rs:WP_024689860	DNA topoisomerase III [Pseudomonas syringae].	27.32	615	406	14	1	585	1	604	1e-64	237
rs:WP_032972638	DNA topoisomerase III [Bordetella hinzii].	26.97	660	436	17	1	629	1	645	1e-64	237
tr:G0LYH7_LACPE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.08	619	399	15	3	592	4	611	1e-64	238
rs:WP_042876255	DNA topoisomerase III, partial [Bacillus cereus].	33.82	550	317	17	107	627	1	532	1e-64	236
rs:WP_018752813	DNA topoisomerase III [Paenibacillus sanguinis].	26.26	735	445	23	3	654	4	724	1e-64	239
rs:WP_011374468	DNA topoisomerase III [Lactobacillus sakei].	29.13	618	391	13	2	610	4	583	1e-64	238
tr:E1JMD1_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.67	562	327	14	2	547	3	523	1e-64	234
rs:WP_044784436	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	27.73	732	453	19	3	676	7	720	1e-64	240
tr:W1EZD8_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.34	431	246	11	1	401	1	424	1e-64	233
rs:WP_000214012	DNA topoisomerase III [Staphylococcus aureus].	28.97	711	443	22	3	676	5	690	1e-64	238
tr:G0F0R0_CUPNN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.87	679	423	21	41	677	2	662	1e-64	240
rs:WP_044345499	DNA topoisomerase III [Pseudomonas meliae].	27.15	663	431	16	1	629	1	645	1e-64	237
tr:W8YT76_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.07	618	371	21	3	581	4	605	1e-64	240
rs:WP_016121292	DNA topoisomerase III [Bacillus cereus].	28.35	723	453	21	4	678	6	711	1e-64	238
rs:WP_035783947	DNA topoisomerase [Butyrivibrio sp. MC2021].	27.36	753	463	23	2	679	4	747	1e-64	242
rs:WP_042253442	topoisomerase I [Lactobacillus brevis].	29.44	608	389	16	3	581	4	600	1e-64	238
rs:WP_036952801	DNA topoisomerase, partial [Pseudobutyrivibrio ruminis].	27.12	767	466	26	2	685	4	760	1e-64	239
rs:WP_010681314	DNA topoisomerase [Acetivibrio cellulolyticus].	29.50	634	383	17	3	580	5	630	1e-64	237
rs:WP_025481450	DNA topoisomerase III [Enterococcus faecium].	27.46	681	433	18	3	639	4	667	1e-64	237
rs:WP_004585380	DNA topoisomerase [Porphyromonas gingivalis].	28.87	710	456	22	1	684	1	687	2e-64	238
rs:WP_036849905	DNA topoisomerase I [Porphyromonas macacae].	29.14	707	458	20	1	684	1	687	2e-64	238
rs:WP_023043254	DNA topoisomerase III [Enterococcus faecium].	27.61	681	432	18	3	639	4	667	2e-64	237
rs:WP_041072541	DNA topoisomerase III [Bacillus sp. OxB-1].	26.52	705	482	14	3	676	4	703	2e-64	238
rs:WP_044323396	DNA topoisomerase III [Pseudomonas amygdali].	27.40	624	408	14	1	592	1	611	2e-64	237
tr:Q3MN26_LACPA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.61	608	388	16	3	581	4	600	2e-64	238
rs:WP_036623080	DNA topoisomerase III [Paenibacillus macerans].	26.62	725	439	20	3	647	4	715	2e-64	239
rs:WP_003660153	DNA topoisomerase III [Lactobacillus paracasei].	29.44	608	389	16	3	581	4	600	2e-64	238
rs:WP_029485280	DNA topoisomerase [Enterococcus faecium].	28.53	715	452	21	3	673	4	703	2e-64	238
rs:WP_016171196	DNA topoisomerase III [Enterococcus faecium].	27.61	681	432	18	3	639	4	667	2e-64	237
rs:WP_043461343	hypothetical protein, partial [Azohydromonas australica].	27.72	736	446	29	3	675	4	716	2e-64	238
rs:WP_009668885	DNA topoisomerase III [gamma proteobacterium IMCC1989].	29.75	642	384	16	1	581	1	636	2e-64	237
rs:WP_016203107	DNA topoisomerase [Bacillus nealsonii].	29.78	732	432	27	1	679	1	703	2e-64	238
rs:WP_010776544	DNA topoisomerase III [Enterococcus faecium].	28.01	714	457	18	3	673	4	703	2e-64	238
rs:WP_046481675	DNA topoisomerase, partial [Pseudomonas veronii].	29.20	726	428	25	3	668	5	704	2e-64	239
rs:WP_024679664	DNA topoisomerase III [Pseudomonas syringae].	26.97	623	412	13	1	592	1	611	2e-64	236
rs:WP_008015944	DNA topoisomerase, partial [Bacteroides xylanisolvens].	31.95	554	329	17	1	530	1	530	2e-64	234
rs:WP_012108053	DNA topoisomerase III [Campylobacter hominis].	30.19	689	407	23	1	640	1	664	2e-64	238
rs:WP_012701283	DNA topoisomerase III [Azotobacter vinelandii].	26.99	615	399	13	1	581	4	602	2e-64	236
rs:WP_041755624	DNA topoisomerase III [Pseudomonas stutzeri].	26.68	611	407	12	1	581	1	600	2e-64	236
rs:WP_013378047	ATP-dependent DNA helicase RecQ [Stigmatella aurantiaca].	27.27	638	391	15	4	578	28	655	2e-64	243
rs:WP_016078683	DNA topoisomerase 1 [Bacillus cereus].	28.72	672	433	18	32	675	37	690	2e-64	240
rs:WP_014257080	DNA topoisomerase [[Clostridium] clariflavum].	29.50	644	394	17	3	592	5	642	2e-64	236
tr:Q099E1_STIAD	SubName: Full=Topoisomerase B {ECO:0000313|EMBL:EAU68374.1};	27.27	638	391	15	4	578	33	660	2e-64	243
rs:WP_039042607	DNA topoisomerase III [Sporosarcina sp. ZBG7A].	27.08	720	466	19	3	679	4	707	2e-64	237
rs:WP_003441919	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	27.41	613	397	12	1	580	1	598	2e-64	236
rs:WP_044496677	DNA topoisomerase III, partial [Peptoclostridium difficile].	35.01	397	228	10	1	385	1	379	2e-64	230
rs:WP_043861109	DNA topoisomerase III [Pseudomonas putida].	27.70	610	395	13	1	578	1	596	3e-64	236
rs:WP_022113658	DNA topoisomerase [Clostridium sp. CAG:245].	29.04	644	385	18	3	579	5	643	3e-64	236
rs:WP_023008797	DNA topoisomerase III [Marinobacter sp. EVN1].	28.59	647	418	15	1	614	1	636	3e-64	238
rs:WP_034930384	DNA topoisomerase III [Candidatus Accumulibacter sp. SK-01].	27.99	736	436	28	2	676	4	706	3e-64	239
rs:WP_044061218	DNA topoisomerase III [Pseudomonas aeruginosa].	27.09	646	419	15	1	614	1	626	3e-64	236
rs:WP_044999629	DNA topoisomerase III [Roseburia intestinalis].	32.42	549	322	17	148	673	13	535	3e-64	234
rs:WP_016647531	DNA topoisomerase III [Campylobacter ureolyticus].	30.04	689	408	22	1	640	1	664	3e-64	237
rs:WP_002553877	DNA topoisomerase III [Pseudomonas savastanoi].	27.40	624	408	14	1	592	1	611	3e-64	236
tr:E5VST4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	31.87	502	303	14	2	481	4	488	3e-64	232
rs:WP_045183922	DNA topoisomerase III [Pseudomonas sp. 5].	27.35	607	401	12	1	578	1	596	3e-64	236
rs:WP_002347713	DNA topoisomerase III [Enterococcus faecium].	27.61	681	432	18	3	639	4	667	3e-64	236
rs:WP_006803319	DNA topoisomerase III [Helicobacter winghamensis].	30.42	687	412	25	1	640	1	668	3e-64	237
rs:WP_036943638	DNA topoisomerase [Pseudobacteroides cellulosolvens].	29.16	631	389	15	3	580	5	630	3e-64	236
rs:WP_042773587	hypothetical protein, partial [Salmonella enterica].	29.42	656	420	17	3	629	6	647	3e-64	236
rs:WP_040763483	DNA topoisomerase, partial [Sutterella parvirubra].	28.12	640	387	17	2	578	4	633	3e-64	236
rs:WP_035546994	DNA topoisomerase III [Halobacillus sp. BBL2006].	28.02	703	433	16	3	658	5	681	3e-64	237
rs:WP_003180391	DNA topoisomerase III [Pseudomonas fluorescens].	27.29	612	395	14	1	578	1	596	3e-64	236
rs:WP_008077315	DNA topoisomerase III [Pseudomonas sp. GM80].	27.42	609	402	12	1	580	1	598	3e-64	236
rs:WP_044527626	DNA topoisomerase III [Escherichia coli].	28.45	717	452	19	1	673	1	700	3e-64	237
rs:WP_024669068	DNA topoisomerase III [Pseudomonas syringae].	27.32	615	406	14	1	585	1	604	3e-64	236
rs:WP_025476753	DNA topoisomerase [Enterococcus faecium].	28.25	715	454	20	3	673	4	703	3e-64	238
rs:WP_010688141	DNA topoisomerase III [Lactobacillus animalis].	28.75	647	398	17	2	630	3	604	3e-64	236
rs:WP_002429351	DNA topoisomerase III, partial [Yersinia pestis].	30.60	536	321	20	1	500	1	521	4e-64	233
rs:WP_036723764	DNA topoisomerase III, partial [Paenibacillus forsythiae].	29.76	615	371	22	3	577	4	597	4e-64	235
rs:WP_042748761	topoisomerase I [Lactococcus lactis].	28.69	725	449	24	3	675	4	712	4e-64	237
rs:WP_005893387	DNA topoisomerase III [Pseudomonas coronafaciens].	26.99	615	408	12	1	585	1	604	4e-64	236
rs:WP_016312076	DNA topoisomerase III [Paenibacillus barengoltzii].	27.60	732	421	25	3	647	4	713	4e-64	238
rs:WP_034697924	DNA topoisomerase [Enterococcus hirae].	28.31	717	455	19	3	675	4	705	4e-64	237
rs:WP_016208465	DNA topoisomerase III [Clostridium sartagoforme].	31.19	638	363	23	3	580	5	626	4e-64	236
rs:WP_025240834	DNA topoisomerase III [Pseudomonas stutzeri].	27.33	611	397	14	1	578	1	597	4e-64	236
rs:WP_044051694	DNA topoisomerase, partial [Enterococcus faecium].	28.53	638	401	14	3	600	4	626	4e-64	235
rs:WP_027977778	DNA topoisomerase III [gamma proteobacterium L18].	27.04	614	398	13	1	580	1	598	4e-64	236
rs:WP_007159931	DNA topoisomerase III [Pseudomonas psychrotolerans].	27.16	626	407	15	1	592	1	611	4e-64	236
rs:WP_005874605	DNA topoisomerase I [Porphyromonas gingivalis].	28.63	709	459	21	1	684	1	687	4e-64	236
tr:A6G6C2_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.21	638	391	20	3	585	4	629	4e-64	242
rs:WP_045116179	hypothetical protein [Plesiocystis pacifica].	28.21	638	391	20	3	585	12	637	4e-64	242
rs:WP_024647114	DNA topoisomerase III [Pseudomonas syringae].	27.76	616	402	16	1	585	1	604	4e-64	236
rs:WP_026882027	DNA topoisomerase [Clostridium akagii].	29.01	724	453	22	2	680	3	710	4e-64	237
rs:WP_016475275	DNA topoisomerase III [Sutterella wadsworthensis].	27.69	733	440	25	3	680	5	702	4e-64	239
rs:WP_028537582	DNA topoisomerase III [Paenibacillus sp. J14].	28.19	635	407	17	3	603	4	623	4e-64	238
rs:WP_046162109	DNA topoisomerase III [Pseudomonas sp. 10B238].	27.45	612	395	13	1	578	1	597	4e-64	236
rs:WP_002322496	DNA topoisomerase III [Enterococcus faecium].	27.46	681	433	18	3	639	4	667	4e-64	236
rs:WP_014717974	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	27.38	610	401	12	1	580	1	598	4e-64	236
rs:WP_029863194	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	30.27	555	348	14	2	524	3	550	4e-64	233
rs:WP_024781366	DNA topoisomerase III [Pseudomonas corrugata].	26.93	609	401	13	1	578	1	596	4e-64	235
rs:WP_031885094	DNA topoisomerase III [Staphylococcus aureus].	28.97	711	443	22	3	676	5	690	4e-64	236
rs:WP_019393159	MULTISPECIES: DNA topoisomerase [Bacillus].	29.77	729	434	26	1	678	1	702	4e-64	237
tr:F3C4Q0_PSESG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.29	623	410	14	1	592	1	611	4e-64	236
rs:WP_011763832	DNA topoisomerase III [Azoarcus sp. BH72].	28.14	725	446	24	2	676	4	703	4e-64	239
rs:WP_000765173	DNA topoisomerase III [Escherichia coli].	28.45	717	452	19	1	673	1	700	5e-64	237
rs:WP_045492462	DNA topoisomerase III [Pseudomonas sp. StFLB209].	26.52	607	406	11	1	578	1	596	5e-64	236
tr:F3CKY0_PSESG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	27.87	610	401	13	1	581	1	600	5e-64	234
rs:WP_024696781	DNA topoisomerase III [Pseudomonas syringae].	26.85	622	414	14	1	592	1	611	5e-64	236
rs:WP_044288115	DNA topoisomerase III [Pseudomonas fluorescens].	27.80	615	392	13	1	580	1	598	5e-64	235
rs:WP_011237227	DNA topoisomerase III [Aromatoleum aromaticum].	27.33	611	411	11	1	585	1	604	5e-64	236
rs:WP_040069566	DNA topoisomerase III [Pseudomonas batumici].	26.60	639	422	12	1	608	1	623	5e-64	235
rs:WP_021166216	hypothetical protein [Lactococcus lactis].	28.69	725	449	24	3	675	4	712	5e-64	237
rs:WP_025389477	DNA topoisomerase III [Pseudomonas syringae].	27.60	616	403	15	1	585	1	604	5e-64	235
rs:WP_020736077	ATP-dependent DNA helicase RecQ [Sorangium cellulosum].	27.53	672	387	19	1	581	1	663	5e-64	242
rs:WP_025214575	DNA topoisomerase III [Pseudomonas brassicacearum].	27.21	610	398	14	1	578	1	596	5e-64	235
rs:WP_002303486	DNA topoisomerase III [Enterococcus faecium].	27.46	681	433	18	3	639	4	667	6e-64	236
rs:WP_042236846	DNA topoisomerase III [Paenibacillus sp. FSL R5-0912].	27.40	759	443	28	3	673	4	742	6e-64	237
rs:WP_014748829	DNA topoisomerase [Enterococcus faecium].	28.53	638	401	14	3	600	4	626	6e-64	235
gp:CP010896_1975	DNA topoisomerase III [Pseudomonas fluorescens]	27.80	615	392	13	1	580	3	600	6e-64	235
tr:W4RYY9_9XANT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.34	621	386	16	50	629	1	603	6e-64	234
rs:WP_017339501	DNA topoisomerase III [Pseudomonas fluorescens].	27.33	611	400	12	1	580	1	598	6e-64	235
rs:WP_008679608	DNA topoisomerase III [Clostridium sp. 7_2_43FAA].	32.29	638	356	24	3	580	5	626	6e-64	235
rs:WP_033902057	DNA topoisomerase III [Pseudomonas sp. FH1].	27.48	615	394	13	1	580	1	598	6e-64	235
rs:WP_019875135	DNA topoisomerase [Lactobacillus paracasei].	28.62	608	394	14	3	581	4	600	6e-64	236
rs:WP_014642662	DNA topoisomerase III [Halobacillus halophilus].	28.53	708	436	17	3	664	5	688	6e-64	236
rs:WP_044503985	DNA topoisomerase [Megasphaera sp. NP3].	28.57	644	414	16	1	615	1	627	6e-64	236
rs:WP_010890637	protein TrsI [Lactococcus lactis].	28.69	725	449	24	3	675	4	712	6e-64	236
rs:WP_046027642	DNA topoisomerase III [Pseudomonas fluorescens].	27.05	610	403	13	1	580	1	598	7e-64	235
rs:WP_047000790	DNA topoisomerase III [Clostridium beijerinckii].	31.19	638	363	23	3	580	5	626	7e-64	235
rs:WP_038441873	DNA topoisomerase III [Pseudomonas fluorescens].	28.03	610	397	12	1	580	1	598	7e-64	235
rs:WP_002341526	DNA topoisomerase III [Enterococcus faecium].	27.46	681	433	18	3	639	4	667	7e-64	235
rs:WP_034909951	DNA topoisomerase, partial [Peptostreptococcaceae bacterium OBRC8].	33.33	486	280	12	1	472	1	456	7e-64	230
rs:WP_010737556	MULTISPECIES: DNA topoisomerase [Enterococcus].	28.45	717	454	19	3	675	4	705	7e-64	236
rs:WP_032824678	topoisomerase I [Oenococcus oeni].	28.51	698	456	18	3	667	4	691	7e-64	236
rs:WP_024269754	DNA topoisomerase III [Escherichia coli].	33.87	431	248	10	1	401	1	424	8e-64	230
rs:WP_042145203	DNA topoisomerase [Paucisalibacillus sp. EB02].	29.74	723	445	25	1	678	1	705	8e-64	236
rs:WP_024221956	DNA topoisomerase III [Escherichia coli].	28.45	717	452	19	1	673	1	700	8e-64	236
tr:R9MBF0_9FIRM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOS68163.1};	30.46	545	344	11	145	673	10	535	8e-64	233
rs:WP_002824608	DNA topoisomerase [Oenococcus oeni].	28.51	705	447	19	3	667	4	691	8e-64	236
rs:WP_015639749	DNA topoisomerase III [Lactobacillus plantarum].	29.08	619	399	17	3	592	4	611	8e-64	235
rs:WP_022408234	DNA topoisomerase [Clostridium sp. CAG:354].	30.74	631	373	19	3	579	5	625	8e-64	234
tr:K6KZQ0_KLEOX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.42	512	305	19	1	481	1	502	8e-64	231
rs:WP_004165034	DNA topoisomerase [Oenococcus oeni].	28.26	697	459	17	3	667	4	691	8e-64	236
rs:WP_046620732	DNA topoisomerase III [Pseudomonas stutzeri].	26.46	616	402	12	1	581	1	600	8e-64	234
rs:WP_046504073	DNA topoisomerase III [Paenibacillus riograndensis].	26.85	771	449	28	3	678	4	754	8e-64	237
rs:WP_041931602	DNA topoisomerase III [Pseudomonas poae].	27.75	609	396	12	1	578	1	596	9e-64	234
rs:WP_041142920	topoisomerase I, partial [Lactobacillus plantarum].	29.08	619	399	17	3	592	4	611	9e-64	235
tr:C9BZ11_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.46	681	433	18	3	639	34	697	9e-64	236
rs:WP_007997338	DNA topoisomerase III [Pseudomonas sp. GM49].	26.82	619	402	14	1	584	4	606	9e-64	234
rs:WP_002332865	DNA topoisomerase III [Enterococcus faecium].	27.46	681	433	18	3	639	4	667	9e-64	235
rs:WP_039255204	DNA topoisomerase III [Clostridium novyi].	27.77	749	449	23	3	673	5	739	9e-64	236
rs:WP_035854511	DNA topoisomerase III [Dechloromonas agitata].	27.75	728	434	25	2	669	4	699	9e-64	238
rs:WP_019690070	DNA topoisomerase III [Pseudomonas fluorescens].	27.09	609	404	11	1	580	1	598	9e-64	234
rs:WP_033918639	hypothetical protein [Enterococcus faecalis].	29.38	691	437	20	3	654	4	682	9e-64	236
rs:WP_020565900	hypothetical protein [Methylosarcina fibrata].	27.78	648	420	15	1	614	1	634	9e-64	236
rs:WP_034127261	DNA topoisomerase III [Pseudomonas fluorescens].	27.21	610	402	12	1	580	1	598	1e-63	234
rs:WP_018969030	hypothetical protein [Rubritalea marina].	27.42	733	466	23	3	684	5	722	1e-63	238
rs:WP_032958220	DNA topoisomerase III [Bordetella hinzii].	26.89	662	434	18	1	629	1	645	1e-63	235
rs:WP_045792448	DNA topoisomerase III [Pseudomonas fluorescens].	27.71	617	390	14	1	580	1	598	1e-63	234
rs:WP_019364747	hypothetical protein [Pseudomonas luteola].	26.13	708	469	16	3	668	6	701	1e-63	236
gp:CP005975_5245	DNA topoisomerase III [Pseudomonas fluorescens PICF7]	27.71	617	390	14	1	580	3	600	1e-63	234
rs:WP_009589194	DNA topoisomerase III [Paenibacillus sp. HGF5].	27.22	753	450	25	3	673	4	740	1e-63	236
rs:WP_021248574	DNA topoisomerase III [Thauera terpenica].	27.60	663	428	18	1	629	1	645	1e-63	235
rs:WP_021956985	DNA topoisomerase [Eubacterium sp. CAG:115].	28.79	719	439	25	1	680	1	685	1e-63	235
rs:WP_001995833	DNA topoisomerase III [Bacillus cereus].	27.73	732	453	19	3	676	7	720	1e-63	237
rs:WP_009408843	DNA topoisomerase III [Pseudomonas putida].	27.30	608	400	14	1	578	1	596	1e-63	234
rs:WP_024061224	DNA topoisomerase [Veillonella dispar].	28.70	648	402	16	1	596	1	640	1e-63	236
rs:WP_024656059	DNA topoisomerase III [Pseudomonas syringae].	26.81	623	413	14	1	592	1	611	1e-63	234
rs:WP_002301798	DNA topoisomerase III [Enterococcus faecium].	27.46	681	433	18	3	639	4	667	1e-63	235
rs:WP_022517670	DNA topoisomerase [Roseburia sp. CAG:100].	26.02	761	477	19	2	683	4	757	1e-63	240
rs:WP_032849733	DNA topoisomerase I [Bacteroides sp. 2_2_4].	28.17	639	417	14	68	683	2	621	1e-63	234
tr:J4WI89_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.26	487	281	12	1	473	1	457	1e-63	230
rs:WP_008600558	DNA topoisomerase III [Veillonella sp. 6_1_27].	28.70	683	405	19	1	612	1	672	1e-63	236
rs:WP_035140704	DNA topoisomerase [Clostridium tetani].	28.57	728	450	23	2	681	3	708	1e-63	236
rs:WP_032823667	topoisomerase I [Oenococcus oeni].	28.37	705	448	19	3	667	4	691	1e-63	236
rs:WP_023438760	DNA topoisomerase I [Clostridium tetani].	28.71	728	449	24	2	681	3	708	1e-63	236
tr:C3R196_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.02	653	427	15	54	683	7	639	1e-63	234
rs:WP_008713605	DNA topoisomerase III [Veillonella sp. 3_1_44].	28.70	648	402	16	1	596	1	640	1e-63	236
rs:WP_033042013	DNA topoisomerase III [Pseudomonas putida].	26.97	623	412	13	1	592	1	611	1e-63	234
rs:WP_005434089	DNA topoisomerase III [Sutterella wadsworthensis].	27.36	720	459	23	1	679	3	699	1e-63	237
rs:WP_010096889	DNA topoisomerase [Ornithinibacillus scapharcae].	29.05	723	450	22	1	678	1	705	1e-63	236
rs:WP_038059221	hypothetical protein, partial [Thiobacillus denitrificans].	26.85	622	400	17	41	614	3	617	1e-63	234
rs:WP_027600619	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	27.17	611	397	14	1	578	1	596	1e-63	234
rs:WP_035447780	DNA topoisomerase III [Lactobacillus animalis].	28.75	647	398	17	2	630	3	604	1e-63	235
tr:Q893I6_CLOTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.57	728	450	23	2	681	5	710	1e-63	235
rs:WP_032870234	DNA topoisomerase III [Pseudomonas fluorescens].	27.75	609	396	12	1	578	1	596	1e-63	234
rs:WP_022112818	DNA topoisomerase [Roseburia intestinalis CAG:13].	26.30	749	473	19	3	679	5	746	1e-63	240
tr:A0A0A7U658_LACBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.25	612	385	17	3	581	4	600	1e-63	235
rs:WP_016511107	DNA topoisomerase III [Lactobacillus plantarum].	29.11	608	391	17	3	581	4	600	1e-63	235
tr:L7HKF7_PSEFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.75	609	396	12	1	578	3	598	2e-63	234
rs:WP_020485826	hypothetical protein [Methylomonas sp. MK1].	28.31	650	414	15	1	614	1	634	2e-63	236
rs:WP_010211314	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	27.64	615	393	13	1	580	1	598	2e-63	234
rs:WP_003428725	DNA topoisomerase [Clostridium butyricum].	28.14	732	444	24	2	679	3	706	2e-63	235
rs:WP_036978530	DNA topoisomerase, partial [Pseudobutyrivibrio sp. MD2005].	26.80	765	458	26	3	679	5	755	2e-63	236
tr:H3KDU7_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	28.12	640	387	17	2	578	4	633	2e-63	236
rs:WP_034097216	DNA topoisomerase III [Pseudomonas fluorescens].	27.87	610	398	12	1	580	1	598	2e-63	234
rs:WP_019423903	DNA topoisomerase III [Paenibacillus sp. OSY-SE].	28.93	629	371	18	3	577	4	610	2e-63	236
tr:A0A0D3RLA6_LACRE	SubName: Full=TrsI, DNA Topoisomerase {ECO:0000313|EMBL:AJS10517.1};	29.28	608	390	15	3	581	4	600	2e-63	235
rs:WP_042571552	DNA topoisomerase III [Pseudomonas simiae].	27.73	613	391	13	1	578	1	596	2e-63	234
rs:WP_005617548	DNA topoisomerase III [Pseudomonas avellanae].	26.62	616	409	12	1	585	1	604	2e-63	234
rs:WP_009491930	DNA topoisomerase III [Catellicoccus marimammalium].	29.90	622	384	16	2	614	3	581	2e-63	234
rs:WP_036655982	DNA topoisomerase III [Paenibacillus wynnii].	28.66	614	379	19	3	577	4	597	2e-63	236
rs:WP_043190411	DNA topoisomerase III [Pseudomonas rhizosphaerae].	27.38	610	403	12	1	581	1	599	2e-63	233
rs:WP_031291485	DNA topoisomerase III [Pseudomonas fluorescens].	27.64	615	393	13	1	580	1	598	2e-63	234
rs:WP_044383536	DNA topoisomerase [Enterococcus faecium].	27.46	681	433	18	3	639	4	667	2e-63	234
rs:WP_020997000	DNA topoisomerase III, partial [Haemophilus parasuis].	30.88	544	338	15	1	514	1	536	2e-63	231
tr:A0A031GBJ2_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.11	616	406	12	1	587	1	602	2e-63	233
rs:WP_046483316	DNA topoisomerase III [Pseudomonas veronii].	27.05	610	403	12	1	580	1	598	2e-63	234
rs:WP_043664505	DNA topoisomerase [Clostridium butyricum].	28.16	735	440	24	2	679	3	706	2e-63	235
rs:WP_000520732	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	28.81	670	435	19	32	675	37	690	2e-63	237
rs:WP_039930399	DNA topoisomerase III, partial [Anaerostipes sp. 3_2_56FAA].	31.61	503	301	14	2	480	4	487	2e-63	230
rs:WP_002823296	DNA topoisomerase [Oenococcus oeni].	28.37	705	448	19	3	667	4	691	2e-63	235
rs:WP_031323200	DNA topoisomerase III [Pseudomonas stutzeri].	26.96	612	404	12	1	581	1	600	2e-63	234
rs:WP_025698624	DNA topoisomerase III, partial [Paenibacillus durus].	32.89	453	279	11	3	441	4	445	2e-63	229
rs:WP_038291301	DNA topoisomerase [[Clostridium] straminisolvens].	29.95	631	383	19	2	580	4	627	2e-63	234
tr:U1S6K3_PSEFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.64	615	393	13	1	580	3	600	2e-63	234
rs:WP_035762558	DNA topoisomerase [Clostridium butyricum].	28.01	732	445	24	2	679	3	706	2e-63	235
rs:WP_026905925	DNA topoisomerase [Paucisalibacillus globulus].	29.71	727	444	25	1	680	1	707	2e-63	235
rs:WP_044953325	DNA topoisomerase III [Faecalibacterium prausnitzii].	31.40	551	346	13	138	671	1	536	2e-63	231
rs:WP_002818003	DNA topoisomerase [Oenococcus oeni].	28.37	705	448	19	3	667	4	691	2e-63	235
rs:WP_035109339	DNA topoisomerase [Clostridium tetani].	28.57	728	450	23	2	681	3	708	2e-63	235
rs:WP_035125039	DNA topoisomerase [Clostridium tetani].	28.57	728	450	23	2	681	3	708	2e-63	235
rs:WP_038851309	DNA topoisomerase III [Pseudomonas fluorescens].	27.24	613	398	13	1	580	1	598	2e-63	233
rs:WP_038100411	DNA topoisomerase III [Vagococcus lutrae].	29.11	584	363	16	41	610	3	549	2e-63	234
rs:WP_034137853	DNA topoisomerase III [Pseudomonas fluorescens].	27.87	610	398	12	1	580	1	598	2e-63	233
rs:WP_002821023	DNA topoisomerase [Oenococcus oeni].	28.37	705	448	19	3	667	4	691	2e-63	235
tr:W6M0Y1_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.67	660	392	17	4	580	5	655	2e-63	239
rs:WP_033154848	DNA topoisomerase, partial [Pseudobutyrivibrio ruminis].	27.32	765	456	25	2	679	4	755	2e-63	236
rs:WP_032886647	DNA topoisomerase III [Pseudomonas sp. RIT357].	27.50	611	399	12	1	580	1	598	2e-63	233
rs:WP_024040672	DNA topoisomerase [Clostridium butyricum].	28.03	735	441	24	2	679	3	706	2e-63	235
rs:WP_027634967	DNA topoisomerase [Clostridium butyricum].	28.03	735	441	24	2	679	3	706	2e-63	235
rs:WP_002579403	DNA topoisomerase III [Clostridium butyricum].	28.03	735	441	24	2	679	3	706	2e-63	234
tr:A0A061JJ33_PSEST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.80	612	405	13	1	581	13	612	3e-63	233
rs:WP_034148898	DNA topoisomerase III [Pseudomonas fluorescens].	26.87	614	399	12	1	580	1	598	3e-63	233
rs:WP_002857817	DNA topoisomerase III [Campylobacter jejuni].	29.38	725	434	23	1	669	1	703	3e-63	235
rs:WP_011722358	MULTISPECIES: DNA topoisomerase III [Clostridium].	27.94	748	449	23	3	673	5	739	3e-63	235
rs:WP_042177283	DNA topoisomerase III [Paenibacillus sp. FSL R7-0331].	30.68	616	364	22	3	577	4	597	3e-63	235
rs:WP_032822357	topoisomerase I [Oenococcus oeni].	28.37	705	448	19	3	667	4	691	3e-63	234
rs:WP_044649609	DNA topoisomerase III, partial [Klebsiella variicola].	32.37	519	322	13	89	581	20	535	3e-63	232
gp:AE011190_192	DNA topoisomerase [Bacillus anthracis str. A2012]	27.84	704	459	18	3	675	12	697	3e-63	236
rs:WP_040269467	DNA topoisomerase III [Pseudomonas rhodesiae].	27.70	610	399	12	1	580	1	598	3e-63	233
rs:WP_042266884	DNA topoisomerase III [Paenibacillus graminis].	26.98	771	448	27	3	678	4	754	3e-63	235
rs:WP_020798536	DNA topoisomerase III [Pseudomonas sp. G5(2012)].	26.97	623	412	13	1	592	1	611	3e-63	233
tr:X5NVB0_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.67	600	356	17	65	644	14	567	3e-63	233
rs:WP_012864143	DNA topoisomerase III [Veillonella parvula].	29.37	606	374	16	1	557	1	601	3e-63	235
rs:WP_019821417	DNA topoisomerase III [Pseudomonas sp. CFT9].	27.21	610	402	12	1	580	1	598	3e-63	233
tr:J2UTB3_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.79	627	408	13	1	592	5	615	3e-63	233
rs:WP_040109448	DNA topoisomerase III [Jeotgalibacillus sp. D5].	29.07	712	430	26	3	679	7	678	3e-63	235
rs:WP_024236378	DNA topoisomerase III [Escherichia coli].	29.13	714	450	18	1	673	1	699	3e-63	234
rs:WP_018704325	MULTISPECIES: hypothetical protein [Veillonellaceae].	28.65	726	446	22	2	679	3	704	3e-63	234
rs:WP_017709126	DNA topoisomerase III [Pseudomonas syringae].	26.62	616	409	12	1	585	1	604	3e-63	233
rs:WP_044504807	DNA topoisomerase III [Megasphaera sp. NP3].	28.68	638	412	17	1	610	1	623	3e-63	234
rs:WP_035408325	DNA topoisomerase III [Bacillus sp. SJS].	30.42	641	400	17	1	610	1	626	3e-63	234
rs:WP_008046973	DNA topoisomerase III [Pseudomonas sp. GM74].	26.79	627	408	13	1	592	4	614	3e-63	233
rs:WP_042137824	DNA topoisomerase III [Paenibacillus sp. FSL P4-0081].	27.38	756	447	27	3	673	4	742	3e-63	235
rs:WP_015639657	DNA topoisomerase III [Lactobacillus plantarum].	29.28	608	390	17	3	581	4	600	3e-63	234
rs:WP_046057802	DNA topoisomerase [Clostridium sp. IBUN62F].	28.01	732	445	24	2	679	3	706	3e-63	234
rs:WP_036987227	DNA topoisomerase III, partial [Pseudomonas mendocina].	29.60	554	355	15	1	527	1	546	4e-63	231
rs:WP_029277927	DNA topoisomerase III [Pedobacter borealis].	27.97	615	399	16	1	589	1	597	4e-63	232
rs:WP_024807736	topoisomerase I [Verrucomicrobia bacterium LP2A].	29.63	621	381	21	3	581	5	611	4e-63	236
sp:TOP1_BACAN	RecName: Full=DNA topoisomerase 1; EC=5.99.1.2; AltName: Full=DNA topoisomerase I; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	28.23	666	444	16	32	675	20	673	4e-63	236
rs:WP_004693293	DNA topoisomerase [Veillonella parvula].	28.89	630	394	16	1	581	1	625	4e-63	235
rs:WP_038696442	DNA topoisomerase III [Paenibacillus stellifer].	29.04	613	378	19	3	577	4	597	4e-63	235
rs:WP_038535745	DNA topoisomerase [Bacillus sp. X1(2014)].	28.83	725	449	24	1	678	2	706	4e-63	234
rs:WP_042512118	DNA topoisomerase I [Bacillus cereus].	28.43	707	451	22	3	675	5	690	4e-63	236
rs:WP_033607115	DNA topoisomerase, partial [Enterococcus faecalis].	30.24	625	379	17	3	589	4	609	4e-63	232
rs:WP_046817480	DNA topoisomerase III [Pseudomonas putida].	27.13	623	411	13	1	592	1	611	4e-63	233
rs:WP_033036896	DNA topoisomerase III [Pseudomonas sp. GM102].	26.79	627	408	13	1	592	1	611	4e-63	233
rs:WP_019342298	DNA topoisomerase III [Pseudomonas stutzeri].	27.15	615	399	13	1	578	1	603	4e-63	233
tr:A0A0E0W8Z3_BACAN	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:AFH87063.1};	28.23	666	444	16	32	675	48	701	4e-63	236
tr:J2RM32_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.95	627	407	13	1	592	1	611	4e-63	233
rs:WP_027094431	DNA topoisomerase III [Cohnella thermotolerans].	28.96	625	379	23	3	581	4	609	4e-63	235
rs:WP_032517408	DNA topoisomerase III, partial [Peptoclostridium difficile].	30.33	488	299	13	1	471	1	464	4e-63	228
rs:WP_006036811	DNA topoisomerase III [Paenibacillus curdlanolyticus].	29.20	613	383	19	3	581	4	599	5e-63	235
rs:WP_003366191	DNA topoisomerase III [Clostridium botulinum].	27.77	749	449	24	3	673	5	739	5e-63	234
rs:WP_024855755	DNA topoisomerase III [Lactobacillus brevis].	29.11	608	391	17	3	581	4	600	5e-63	234
rs:WP_007246696	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	27.11	616	406	14	1	585	1	604	5e-63	233
rs:WP_032905030	DNA topoisomerase III [Pseudomonas sp. CF150].	27.05	610	403	12	1	580	1	598	5e-63	233
rs:WP_024689379	DNA topoisomerase III [Pseudomonas syringae].	26.76	624	412	14	1	592	1	611	5e-63	233
rs:WP_030137934	DNA topoisomerase III [Pseudomonas fluorescens].	26.64	608	404	12	1	578	1	596	5e-63	233
rs:WP_000520727	DNA topoisomerase I [Bacillus anthracis].	27.84	704	459	18	3	675	5	690	5e-63	236
rs:WP_032860216	DNA topoisomerase III [Pseudomonas sp. FH4].	27.54	610	400	12	1	580	1	598	5e-63	233
rs:WP_034104239	DNA topoisomerase III [Pseudomonas fluorescens].	27.82	611	397	12	1	580	1	598	5e-63	233
rs:WP_020152122	hypothetical protein [Verrucomicrobia bacterium SCGC AAA300-N18].	29.59	730	435	26	2	684	3	700	5e-63	235
rs:WP_041023653	DNA topoisomerase III [Pseudomonas sp. SHC52].	26.77	609	402	13	1	578	1	596	5e-63	232
rs:WP_022776439	DNA topoisomerase [Butyrivibrio sp. AE2015].	26.90	762	463	22	2	677	4	757	5e-63	238
rs:WP_026503225	DNA topoisomerase III [Bifidobacterium boum].	26.17	745	465	24	1	683	1	722	5e-63	234
rs:WP_041073385	DNA topoisomerase III [Pseudomonas sp. W15Feb9B].	26.89	621	411	13	1	592	1	607	5e-63	232
rs:WP_016526770	DNA topoisomerase [Lactobacillus plantarum].	28.69	718	465	18	3	681	4	713	5e-63	234
rs:WP_033063590	DNA topoisomerase III [Pseudomonas sp. GM48].	26.95	627	407	13	1	592	4	614	5e-63	233
tr:A0A0A4GET4_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.65	623	414	13	1	592	1	611	5e-63	232
rs:WP_040636960	hypothetical protein, partial [Mucispirillum schaedleri].	28.97	725	431	21	1	672	1	694	5e-63	234
rs:WP_021738983	DNA topoisomerase, partial [Eubacterium ramulus].	33.93	389	232	9	28	404	10	385	6e-63	226
rs:WP_042968464	DNA topoisomerase III [Escherichia coli].	29.76	709	440	19	1	668	1	692	6e-63	234
rs:WP_003414269	DNA topoisomerase [Clostridium butyricum].	27.89	735	442	23	2	679	3	706	6e-63	234
rs:WP_026140036	DNA topoisomerase III [Pseudomonas veronii].	26.83	656	425	15	1	613	1	644	6e-63	232
rs:WP_025143486	DNA topoisomerase III [Sphingobacterium sp. H1ai].	27.97	615	399	16	1	589	1	597	6e-63	232
rs:WP_032897514	DNA topoisomerase III [Pseudomonas sp. Eur1 9.41].	27.21	610	402	12	1	580	1	598	6e-63	232
rs:WP_046385324	DNA topoisomerase III [Pseudomonas veronii].	26.83	656	425	15	1	613	1	644	6e-63	232
rs:WP_022367814	DNA topoisomerase III [Firmicutes bacterium CAG:882].	29.20	654	380	19	3	580	5	651	6e-63	233
rs:WP_037476926	DNA topoisomerase III [Sphaerotilus natans].	28.46	671	391	25	3	611	5	648	7e-63	235
rs:WP_032903512	DNA topoisomerase III [Pseudomonas fluorescens].	27.05	610	403	12	1	580	1	598	7e-63	232
rs:WP_017684788	DNA topoisomerase III [Pseudomonas syringae].	26.57	621	413	14	1	590	1	609	7e-63	233
rs:WP_006556993	DNA topoisomerase III [Veillonella ratti].	28.46	650	418	19	1	618	1	635	7e-63	234
rs:WP_032806200	topoisomerase I [Oenococcus oeni].	28.47	706	446	20	3	667	4	691	7e-63	233
rs:WP_019225407	MULTISPECIES: DNA topoisomerase III [Dehalobacter].	28.03	792	434	27	3	676	5	778	8e-63	234
rs:WP_003381830	DNA topoisomerase III [Pseudomonas syringae].	26.79	616	408	14	1	585	1	604	8e-63	232
tr:E0S4A4_BUTPB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.88	739	454	25	3	673	5	732	8e-63	234
rs:WP_026801823	DNA topoisomerase III [Pontibacillus halophilus].	27.22	698	458	16	3	664	5	688	8e-63	233
rs:WP_020325680	DNA topoisomerase III [Pseudomonas syringae].	26.46	616	410	12	1	585	1	604	8e-63	232
rs:WP_008059727	DNA topoisomerase III [Pseudomonas sp. GM78].	26.97	623	412	13	1	592	1	611	8e-63	232
rs:WP_007249706	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	26.79	616	408	12	1	585	1	604	8e-63	232
rs:WP_003173078	DNA topoisomerase III [Pseudomonas fluorescens].	27.21	610	402	12	1	580	1	598	8e-63	232
rs:WP_003226035	DNA topoisomerase III [Pseudomonas fluorescens].	26.69	622	415	14	1	592	1	611	8e-63	232
rs:WP_004697350	DNA topoisomerase [Veillonella parvula].	28.55	683	406	19	1	612	1	672	8e-63	234
rs:WP_021566151	hypothetical protein [Escherichia coli].	28.86	738	451	20	1	683	1	719	8e-63	233
rs:WP_017701728	DNA topoisomerase III [Pseudomonas syringae].	27.11	616	406	14	1	585	1	604	8e-63	232
rs:WP_031770311	DNA topoisomerase III [Staphylococcus aureus].	29.32	723	443	23	3	683	4	700	9e-63	233
rs:WP_017688080	DNA topoisomerase III [Paenibacillus sp. PAMC 26794].	29.66	617	372	21	3	577	4	600	9e-63	234
rs:WP_026771463	DNA topoisomerase [Sediminibacillus halophilus].	29.28	724	447	24	1	678	1	705	9e-63	233
rs:WP_038369398	hypothetical protein [Brackiella oedipodis].	29.79	715	417	24	3	680	4	670	9e-63	232
rs:WP_025436673	DNA topoisomerase [Eubacterium acidaminophilum].	29.61	645	392	17	2	593	4	639	9e-63	232
rs:WP_008435880	DNA topoisomerase III [Pseudomonas sp. Ag1].	27.99	618	398	13	1	587	1	602	9e-63	232
rs:WP_024695632	DNA topoisomerase III [Pseudomonas syringae].	26.76	624	412	14	1	592	1	611	9e-63	232
rs:WP_045487459	DNA topoisomerase III [Bacillus sp. TS-2].	31.34	702	405	28	2	669	5	663	1e-62	232
rs:WP_032807128	topoisomerase I [Oenococcus oeni].	28.33	706	447	20	3	667	4	691	1e-62	233
rs:WP_021979153	DNA topoisomerase [Clostridium sp. CAG:793].	29.57	629	382	15	2	578	24	643	1e-62	232
rs:WP_042958334	DNA topoisomerase, partial [Enterococcus faecium].	34.85	462	270	9	103	557	1	438	1e-62	226
rs:WP_043302582	DNA topoisomerase III [Pseudomonas sp. GM55].	26.79	627	408	13	1	592	4	614	1e-62	232
rs:WP_031896211	DNA topoisomerase III [Staphylococcus aureus].	29.18	723	444	23	3	683	4	700	1e-62	233
rs:WP_009351396	DNA topoisomerase [Veillonella sp. oral taxon 158].	29.04	637	384	17	1	581	1	625	1e-62	234
tr:X0RBQ7_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.34	702	405	28	2	669	6	664	1e-62	232
rs:WP_034112916	DNA topoisomerase III [Pseudomonas fluorescens].	27.70	610	399	12	1	580	1	598	1e-62	231
rs:WP_042559616	DNA topoisomerase III [Pseudomonas fluorescens].	26.60	609	407	12	1	580	1	598	1e-62	231
tr:J2SQG3_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.79	627	408	13	1	592	1	611	1e-62	231
rs:WP_022257932	DNA topoisomerase [Clostridium sp. CAG:508].	29.25	636	380	17	3	578	5	630	1e-62	231
rs:WP_029296576	DNA topoisomerase III [Pseudomonas fluorescens].	27.09	609	404	12	1	580	1	598	1e-62	231
rs:WP_018611357	DNA topoisomerase III [Pseudomonas sp. CFII68].	26.81	608	403	13	1	578	1	596	1e-62	231
rs:WP_003190339	DNA topoisomerase III [Pseudomonas fluorescens].	27.05	610	403	12	1	580	1	598	1e-62	231
rs:WP_032832845	DNA topoisomerase III [Pseudomonas sp. GM67].	27.38	610	401	14	1	580	1	598	1e-62	231
rs:WP_035635729	DNA topoisomerase III [Lachnospiraceae bacterium ND2006].	27.88	660	389	18	3	590	5	649	1e-62	232
rs:WP_033064134	DNA topoisomerase III [Pseudomonas sp. GM18].	26.49	638	424	13	1	608	1	623	1e-62	231
tr:J2TJ40_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.38	610	401	14	1	580	4	601	1e-62	231
tr:V2RK58_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ESJ98103.1};	29.28	724	430	22	1	672	1	694	1e-62	234
rs:WP_007966854	DNA topoisomerase III [Pseudomonas sp. GM30].	26.95	616	407	14	1	587	1	602	1e-62	231
rs:WP_003211612	DNA topoisomerase III [Pseudomonas fluorescens].	27.58	620	398	13	1	587	1	602	1e-62	231
rs:WP_011104028	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	26.79	616	408	13	1	585	1	604	1e-62	232
rs:WP_001235737	DNA topoisomerase III [Salmonella enterica].	28.99	714	451	18	1	673	1	699	1e-62	233
rs:WP_023607195	DNA topoisomerase III, partial [Staphylococcus epidermidis].	31.72	599	345	18	3	560	4	579	1e-62	230
rs:WP_039234196	DNA topoisomerase III [Clostridium sp. K25].	27.08	746	458	18	3	673	5	739	1e-62	233
rs:WP_043293257	DNA topoisomerase III [Pseudomonas sp. LAMO17WK12:I2].	27.21	610	402	12	1	580	1	598	1e-62	231
rs:WP_036845243	DNA topoisomerase I, partial [Porphyromonas sp. COT-108 OH1349].	29.66	644	376	19	1	580	1	631	1e-62	231
tr:J2NSS9_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.49	638	424	13	1	608	4	626	1e-62	231
tr:A0A0C7JSX9_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEO32215.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEO32215.1};	28.20	734	436	28	1	677	1	700	1e-62	233
rs:WP_027625981	DNA topoisomerase III [Clostridium lundense].	28.87	762	438	23	3	673	5	753	1e-62	233
rs:WP_017642366	DNA topoisomerase III [Pseudomonas sp. 313].	27.33	611	396	15	1	578	1	596	2e-62	231
rs:WP_040212160	DNA topoisomerase [Clostridium sp. MS1].	29.02	734	438	29	3	679	5	712	2e-62	233
rs:WP_041474889	DNA topoisomerase III [Pseudomonas sp. UW4].	26.48	623	415	14	1	592	4	614	2e-62	231
rs:WP_016184912	DNA topoisomerase III [Enterococcus sulfureus].	29.37	623	383	13	2	611	3	581	2e-62	232
rs:WP_027955625	DNA topoisomerase III [Halobacillus kuroshimensis].	27.96	701	451	16	3	664	5	690	2e-62	232
rs:WP_044162603	DNA topoisomerase [Salinibacillus aidingensis].	29.46	740	438	26	1	681	1	715	2e-62	233
rs:WP_013710309	DNA topoisomerase III [Carnobacterium sp. 17-4].	27.77	623	393	17	3	611	4	583	2e-62	232
rs:WP_034119183	DNA topoisomerase III [Pseudomonas fluorescens].	27.21	610	402	12	1	580	1	598	2e-62	231
rs:WP_008151456	DNA topoisomerase III [Pseudomonas sp. GM41(2012)].	26.93	609	405	11	1	580	1	598	2e-62	231
rs:WP_015042715	MULTISPECIES: DNA topoisomerase III [Dehalobacter].	27.48	786	443	24	3	676	5	775	2e-62	233
rs:WP_043567723	DNA topoisomerase III [Candidatus Accumulibacter sp. BA-93].	27.05	732	448	27	2	676	4	706	2e-62	234
rs:WP_047351009	DNA topoisomerase III [Diaphorobacter sp. J5-51].	26.51	664	434	17	1	629	1	645	2e-62	231
tr:A0A0B0I044_9BACL	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:KHF34212.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KHF34212.1};	30.43	621	361	23	3	577	4	599	2e-62	232
rs:WP_036726462	DNA topoisomerase III [Paenibacillus sp. FSL R7-277].	26.58	760	451	25	3	673	4	745	2e-62	233
rs:WP_039217288	MULTISPECIES: DNA topoisomerase III [Clostridium].	27.08	746	458	18	3	673	5	739	2e-62	233
rs:WP_042968702	DNA topoisomerase III [Escherichia coli].	26.42	757	461	22	1	677	1	741	2e-62	233
rs:WP_027611731	DNA topoisomerase III [Pseudomonas sp. URIL14HWK12:I6].	26.85	622	414	12	1	592	1	611	2e-62	231
tr:K9NKF5_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.48	623	415	14	1	592	1	611	2e-62	231
rs:WP_024866752	DNA topoisomerase [Butyrivibrio sp. FCS014].	26.12	758	469	23	2	679	4	750	2e-62	236
rs:WP_036590367	DNA topoisomerase III, partial [Paenibacillus sophorae].	28.94	615	376	19	3	577	4	597	2e-62	230
rs:WP_038815648	DNA topoisomerase III [Campylobacter jejuni].	28.97	718	446	21	1	669	1	703	2e-62	232
rs:WP_042705047	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	26.65	623	414	13	1	592	1	611	2e-62	231
rs:WP_002825295	DNA topoisomerase III [Oenococcus oeni].	28.95	608	392	15	3	581	4	600	2e-62	232
tr:D4JPB1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.21	782	468	22	3	685	5	776	2e-62	236
rs:WP_025699539	DNA topoisomerase III, partial [Paenibacillus durus].	29.43	649	385	23	3	605	4	625	2e-62	231
rs:WP_026136771	DNA topoisomerase III [Pseudomonas sp. CBZ-4].	26.97	608	402	12	1	578	1	596	2e-62	231
rs:WP_046213986	DNA topoisomerase III [Paenibacillus wulumuqiensis].	30.29	614	369	22	3	577	4	597	2e-62	233
rs:WP_047293557	DNA topoisomerase III [Pseudomonas fluorescens].	26.53	622	416	13	1	592	1	611	2e-62	231
rs:WP_046048951	DNA topoisomerase III [Pseudomonas fluorescens].	26.72	610	405	12	1	580	1	598	2e-62	231
rs:WP_000765171	DNA topoisomerase III [Escherichia coli].	28.45	717	452	19	1	673	1	700	2e-62	232
rs:WP_017904483	DNA topoisomerase III [Pseudomonas fuscovaginae].	26.11	655	441	12	1	624	1	643	2e-62	231
rs:WP_034135351	DNA topoisomerase III [Pseudomonas fluorescens].	27.05	610	403	12	1	580	1	598	2e-62	231
rs:WP_037319066	hypothetical protein, partial [Ruminobacter sp. RM87].	28.83	607	387	19	2	577	3	595	2e-62	229
rs:WP_032830402	DNA topoisomerase III [Pseudomonas sp. GM79].	26.32	627	411	14	1	592	1	611	2e-62	231
rs:WP_046037339	DNA topoisomerase III [Pseudomonas fluorescens].	26.82	619	402	13	1	584	4	606	2e-62	231
tr:J2MLI7_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.65	623	414	13	1	592	4	614	2e-62	231
rs:WP_010446576	DNA topoisomerase III [Pseudomonas fuscovaginae].	27.00	611	402	12	1	580	1	598	2e-62	231
rs:WP_033054459	DNA topoisomerase III [Pseudomonas mandelii].	27.09	609	404	11	1	580	1	598	2e-62	231
tr:A0A0C7HUT9_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEO05722.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEO05722.1};	28.01	732	440	27	1	677	1	700	2e-62	232
rs:WP_000765170	DNA topoisomerase III [Escherichia coli].	28.45	717	452	19	1	673	1	700	3e-62	232
rs:WP_044704774	DNA topoisomerase III [Escherichia coli].	28.87	717	449	20	1	673	1	700	3e-62	232
rs:WP_014893884	DNA topoisomerase I [Bacillus cereus].	28.14	668	442	16	32	675	37	690	3e-62	233
rs:WP_027909879	DNA topoisomerase III [Pseudomonas sp. URMO17WK12:I4].	27.09	609	404	12	1	580	1	598	3e-62	231
rs:WP_034549119	DNA topoisomerase III [Carnobacterium alterfunditum].	27.68	625	391	16	3	611	4	583	3e-62	231
rs:WP_001235736	DNA topoisomerase III [Escherichia coli].	28.85	714	452	18	1	673	1	699	3e-62	232
rs:WP_044705422	DNA topoisomerase III [Escherichia coli].	26.42	757	461	22	1	677	1	741	3e-62	232
rs:WP_024676485	DNA topoisomerase III [Pseudomonas syringae].	26.46	616	410	14	1	585	1	604	3e-62	231
tr:A0A0C7TBY2_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEQ30985.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEQ30985.1};	28.49	737	430	30	1	677	1	700	3e-62	232
rs:WP_003375986	DNA topoisomerase III [Clostridium botulinum].	26.94	746	459	18	3	673	5	739	3e-62	232
rs:WP_028941765	DNA topoisomerase III [Pseudomonas vranovensis].	26.52	607	406	11	1	578	1	596	3e-62	230
rs:WP_022619468	DNA topoisomerase [Peptoclostridium difficile].	29.63	712	443	22	2	675	3	694	3e-62	231
rs:WP_002588973	DNA topoisomerase III, partial [[Clostridium] clostridioforme].	29.43	615	395	16	85	676	1	599	3e-62	230
tr:J3IDL5_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.32	627	411	14	1	592	5	615	3e-62	230
rs:WP_041326775	DNA topoisomerase III, partial [Ruminococcus champanellensis].	34.22	415	251	11	3	409	4	404	3e-62	225
rs:WP_009899115	DNA topoisomerase [Peptoclostridium difficile].	29.63	712	443	22	2	675	3	694	3e-62	231
rs:WP_036380219	DNA topoisomerase, partial [Mogibacterium timidum].	33.88	484	280	14	1	472	1	456	3e-62	226
rs:WP_022292366	DNA topoisomerase [Eubacterium rectale CAG:36].	25.96	782	470	21	3	685	5	776	3e-62	236
rs:WP_000520728	DNA topoisomerase I [Bacillus cereus].	27.86	707	455	20	3	675	5	690	3e-62	234
rs:WP_036681478	hypothetical protein [Paenibacillus sp. FSL H8-237].	28.25	715	450	20	2	673	4	698	3e-62	234
rs:WP_001235739	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	29.76	709	442	19	1	668	1	694	3e-62	231
rs:WP_001505316	DNA topoisomerase III family protein [Escherichia coli].	28.79	712	445	19	1	668	1	694	3e-62	231
rs:WP_021558908	hypothetical protein [Escherichia coli].	29.21	712	442	19	1	668	1	694	3e-62	231
rs:WP_011334736	DNA topoisomerase III [Pseudomonas fluorescens].	26.94	620	402	13	1	587	1	602	3e-62	230
tr:D8HAD9_BACAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.25	669	440	18	32	675	20	673	3e-62	233
rs:WP_001542045	DNA topoisomerase III [Escherichia coli].	28.45	717	452	19	1	673	1	700	3e-62	231
rs:WP_046072708	DNA topoisomerase III [Pseudomonas fluorescens].	27.05	610	403	12	1	580	1	598	3e-62	230
rs:WP_044798480	DNA topoisomerase I, partial [Bacillus thuringiensis].	28.55	669	438	20	32	675	37	690	3e-62	232
tr:A4N2M3_HAEIF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.39	531	317	15	90	583	1	526	3e-62	228
rs:WP_042840071	DNA topoisomerase III [Salmonella enterica].	28.99	714	451	18	1	673	1	699	3e-62	231
rs:WP_026570600	DNA topoisomerase [Bacillus sp. NSP22.2].	29.14	724	448	24	1	678	1	705	4e-62	231
rs:WP_002597119	DNA topoisomerase III [Clostridium colicanis].	28.40	736	444	25	2	676	3	716	4e-62	231
rs:WP_027925328	DNA topoisomerase III [Pseudomonas sp. URMO17WK12:I12].	26.56	610	406	11	1	580	1	598	4e-62	230
rs:WP_019376132	hypothetical protein [Virgibacillus halodenitrificans].	29.47	733	429	25	1	678	1	700	4e-62	231
rs:WP_000765168	DNA topoisomerase III [Escherichia coli].	29.15	717	447	20	1	673	1	700	4e-62	231
rs:WP_021563361	hypothetical protein [Escherichia coli].	29.15	717	447	20	1	673	1	700	4e-62	231
rs:WP_039472425	DNA topoisomerase I [Pedobacter kyungheensis].	28.20	610	394	17	1	582	1	594	4e-62	229
rs:WP_046535048	DNA topoisomerase III [Candidatus Accumulibacter phosphatis].	27.12	730	438	25	2	670	4	700	4e-62	233
rs:WP_024618692	DNA topoisomerase III [Pseudomonas fluorescens].	26.32	608	406	11	1	578	1	596	4e-62	230
rs:WP_044702341	DNA topoisomerase III, partial [Escherichia coli].	30.86	525	320	19	1	493	1	514	4e-62	227
rs:WP_033692010	DNA topoisomerase I [Bacillus cereus].	27.86	707	455	20	3	675	5	690	4e-62	233
rs:WP_016176677	DNA topoisomerase III [Enterococcus durans].	27.97	715	456	20	3	673	4	703	4e-62	231
rs:WP_045673653	DNA topoisomerase III [Paenibacillus beijingensis].	29.90	612	379	19	3	579	4	600	4e-62	232
tr:A0A0C7QL11_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEP96439.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEP96439.1};	28.01	732	440	27	1	677	1	700	4e-62	231
rs:WP_034947418	DNA topoisomerase III [Candidatus Accumulibacter sp. SK-02].	27.12	730	438	25	2	670	4	700	4e-62	233
rs:WP_046062077	DNA topoisomerase III [Pseudomonas kilonensis].	26.32	608	406	12	1	578	1	596	4e-62	230
rs:WP_017475477	DNA topoisomerase III [Pseudomonas sp. PAMC 26793].	27.83	618	399	13	1	587	1	602	4e-62	230
rs:WP_013855353	DNA topoisomerase III [Lactobacillus kefiranofaciens].	28.41	602	403	12	3	581	4	600	4e-62	231
rs:WP_044421241	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	26.46	616	410	14	1	585	1	604	4e-62	230
rs:WP_007061961	DNA topoisomerase III [Clostridium carboxidivorans].	27.36	764	455	20	3	673	5	761	4e-62	232
tr:X8IV48_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.81	485	281	14	1	473	1	457	4e-62	225
rs:WP_026083050	DNA topoisomerase III [Pseudomonas tolaasii].	27.26	609	399	12	1	578	1	596	4e-62	230
rs:WP_034152903	DNA topoisomerase III [Pseudomonas fluorescens].	27.01	622	413	14	1	592	1	611	4e-62	230
rs:WP_029573705	DNA topoisomerase III, partial [Pseudomonas syringae].	28.42	570	366	12	1	540	1	558	4e-62	228
rs:WP_005738886	DNA topoisomerase III [Pseudomonas amygdali].	26.70	618	408	14	1	585	1	606	4e-62	230
rs:WP_025854478	DNA topoisomerase III [Pseudomonas sp. CHM02].	27.15	615	396	12	1	580	1	598	5e-62	230
tr:A0A0A2VYV2_BEABA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.57	510	316	14	100	581	11	515	5e-62	228
tr:D4LEK1_RUMC1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.22	415	251	11	3	409	4	404	5e-62	225
rs:WP_017812425	hypothetical protein [Paenibacillus sp. A9].	29.43	615	375	21	3	577	4	599	5e-62	232
rs:WP_025111358	DNA topoisomerase III [Pseudomonas sp. H1h].	26.79	616	408	13	1	587	1	602	5e-62	230
rs:WP_038984222	DNA topoisomerase III [Pseudomonas fluorescens].	26.32	627	411	14	1	592	1	611	5e-62	230
rs:WP_005771280	DNA topoisomerase III [Pseudomonas amygdali].	26.79	616	408	13	1	585	1	604	5e-62	230
rs:WP_036949281	DNA topoisomerase, partial [Pseudobutyrivibrio ruminis].	26.41	765	460	24	3	679	5	754	5e-62	232
rs:WP_001562921	DNA topoisomerase III [Escherichia coli].	26.29	757	462	22	1	677	1	741	5e-62	231
rs:WP_012742985	DNA topoisomerase [Eubacterium rectale].	25.96	782	470	21	3	685	5	776	5e-62	236
rs:WP_044317211	DNA topoisomerase III [Escherichia coli].	29.15	717	447	20	1	673	1	700	5e-62	231
rs:WP_005876033	topoisomerase [Enterococcus durans].	27.97	715	456	20	3	673	4	703	5e-62	231
rs:WP_035765999	DNA topoisomerase [Butyrivibrio sp. NC2002].	26.42	757	465	26	2	679	4	747	5e-62	234
rs:WP_046723272	DNA topoisomerase III [Paenibacillus durus].	29.43	649	385	23	3	605	4	625	5e-62	232
rs:WP_044273187	DNA topoisomerase III [Pseudomonas fluorescens].	26.89	610	404	12	1	580	1	598	5e-62	229
rs:WP_042474231	hypothetical protein, partial [Bacillus sp. FF3].	28.59	717	428	23	3	679	4	676	5e-62	230
rs:WP_026526973	DNA topoisomerase III [Butyrivibrio sp. VCD2006].	28.26	697	410	22	3	620	5	690	5e-62	231
rs:WP_046226540	DNA topoisomerase III [Paenibacillus dauci].	28.95	639	395	22	3	601	4	623	5e-62	232
tr:D4VUU6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.37	589	372	13	3	560	4	579	6e-62	229
rs:WP_007946260	DNA topoisomerase III [Pseudomonas sp. GM21].	26.39	610	407	12	1	580	1	598	6e-62	229
rs:WP_027620857	DNA topoisomerase III [Pseudomonas sp. URHB0015].	27.38	610	397	12	1	578	1	596	6e-62	229
rs:WP_046035969	DNA topoisomerase III [Pseudomonas fluorescens].	27.33	611	400	13	1	580	1	598	6e-62	229
rs:WP_014338649	DNA topoisomerase III [Pseudomonas fluorescens].	26.23	610	404	13	1	578	1	596	6e-62	229
tr:F8K840_STRPY	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	32.44	595	347	18	3	580	41	597	6e-62	229
tr:J2T5I3_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.32	627	411	14	1	592	5	615	6e-62	229
rs:WP_029162866	DNA topoisomerase III [Clostridium scatologenes].	26.96	764	458	17	3	673	5	761	6e-62	231
rs:WP_024074508	DNA topoisomerase III [Pseudomonas sp. TKP].	27.14	608	401	12	1	578	1	596	6e-62	229
rs:WP_017124649	DNA topoisomerase III [Pseudomonas gingeri].	26.32	608	406	10	1	578	1	596	6e-62	229
rs:WP_015059543	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	29.15	717	447	21	1	673	1	700	6e-62	231
rs:WP_033704841	DNA topoisomerase [Enterococcus faecium].	27.97	708	456	17	3	667	4	700	6e-62	231
rs:WP_000765172	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	29.15	717	447	20	1	673	1	700	6e-62	231
rs:WP_014112244	DNA topoisomerase III [Oscillibacter valericigenes].	27.70	769	429	27	2	675	4	740	6e-62	231
tr:D6E5U2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.96	782	470	21	3	685	5	776	7e-62	235
tr:C7X7R3_9PORP	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	27.37	665	428	19	45	680	2	640	7e-62	229
rs:WP_043050240	DNA topoisomerase III [Pseudomonas fluorescens].	26.89	610	404	12	1	580	1	598	7e-62	229
tr:A0A0C7G0C3_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEN75959.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEN75959.1};	28.20	734	436	28	1	677	1	700	7e-62	231
rs:WP_039767094	DNA topoisomerase III [Pseudomonas fluorescens].	26.94	620	402	14	1	587	1	602	7e-62	229
rs:WP_019579443	DNA topoisomerase III [Pseudomonas mandelii].	26.48	623	415	13	1	592	1	611	7e-62	229
rs:WP_007950567	DNA topoisomerase III [Pseudomonas sp. GM25].	27.10	620	401	14	1	587	1	602	7e-62	229
rs:WP_020314981	DNA topoisomerase III [Klebsiella pneumoniae].	29.25	735	448	21	1	680	1	718	7e-62	231
rs:WP_032201902	DNA topoisomerase III [Escherichia coli].	29.62	709	443	19	1	668	1	694	7e-62	231
rs:WP_021548626	hypothetical protein [Escherichia coli].	28.83	711	456	18	1	673	1	699	7e-62	231
rs:WP_032834930	DNA topoisomerase III [Pseudomonas sp. GM50].	26.32	627	411	14	1	592	1	611	7e-62	229
rs:WP_028940230	DNA topoisomerase III [Pseudomonas umsongensis].	26.48	623	415	13	1	592	1	611	8e-62	229
rs:WP_031884038	DNA topoisomerase III [Staphylococcus aureus].	29.05	723	445	23	3	683	4	700	8e-62	230
rs:WP_017134367	DNA topoisomerase III [Pseudomonas agarici].	26.07	633	423	13	1	601	1	620	8e-62	229
rs:WP_028548283	DNA topoisomerase III [Paenibacillus sp. UNC451MF].	30.88	599	351	20	3	560	4	580	8e-62	231
tr:S5W9T8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.99	711	452	18	3	667	5	701	8e-62	231
rs:WP_045575207	DNA topoisomerase III [Desulfosporosinus sp. I2].	27.37	771	446	22	2	676	4	756	8e-62	231
rs:WP_016977365	DNA topoisomerase III [Pseudomonas fluorescens].	26.87	614	399	12	1	580	1	598	8e-62	229
rs:WP_002326882	DNA topoisomerase III [Enterococcus faecium].	27.99	711	452	18	3	667	4	700	8e-62	231
rs:WP_042742987	DNA topoisomerase III, partial [Staphylococcus aureus].	32.43	515	315	15	3	502	4	500	8e-62	226
rs:WP_001547190	DNA topoisomerase III [Escherichia coli].	28.73	717	448	19	1	673	1	698	8e-62	230
rs:WP_038366492	DNA topoisomerase III [Pseudomonas chlororaphis].	26.48	623	415	13	1	592	1	611	8e-62	229
rs:WP_042959782	DNA topoisomerase [Enterococcus faecium].	27.99	711	452	18	3	667	4	700	8e-62	231
rs:WP_042964849	DNA topoisomerase III [Campylobacter coli].	29.10	725	436	23	1	669	1	703	9e-62	231
rs:WP_007124650	DNA topoisomerase, partial [Lactobacillus antri].	29.70	569	361	14	41	581	1	558	9e-62	229
rs:WP_021034341	hypothetical protein [Campylobacter coli].	29.24	725	435	23	1	669	1	703	9e-62	230
rs:WP_044935049	DNA topoisomerase, partial [Pseudobutyrivibrio sp. LB2011].	26.83	764	461	25	2	679	4	755	9e-62	231
tr:D4RK56_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.97	708	456	17	3	667	5	701	9e-62	231
rs:WP_046056719	DNA topoisomerase III [Pseudomonas fluorescens].	26.77	609	406	12	1	580	1	598	9e-62	229
rs:WP_027098238	DNA topoisomerase [Clostridium paraputrificum].	27.53	730	451	22	2	679	3	706	1e-61	230
rs:WP_021885805	DNA topoisomerase [Clostridium sp. CAG:590].	30.23	655	382	25	3	594	14	656	1e-61	229
rs:WP_020492503	DNA topoisomerase III [Dehalobacter sp. FTH1].	27.69	762	448	22	3	676	5	751	1e-61	231
rs:WP_000520736	DNA topoisomerase I [Bacillus thuringiensis].	28.39	701	455	19	3	673	5	688	1e-61	232
rs:WP_000765166	DNA topoisomerase III [Escherichia coli].	28.84	735	451	21	1	680	1	718	1e-61	230
rs:WP_005213949	DNA topoisomerase [Clostridium celatum].	28.77	737	438	29	2	679	3	711	1e-61	230
rs:WP_025481300	DNA topoisomerase [Enterococcus faecium].	27.82	708	457	17	3	667	4	700	1e-61	230
rs:WP_032249640	DNA topoisomerase III [Escherichia coli].	29.12	735	449	21	1	680	1	718	1e-61	230
rs:WP_021243382	conjugal transfer protein TraE [Sphingobium baderi].	27.44	645	416	14	3	614	6	631	1e-61	230
rs:WP_025494540	DNA topoisomerase III, partial [Lachnospiraceae bacterium VE202-12].	31.52	422	263	9	3	414	7	412	1e-61	224
rs:WP_001687633	DNA topoisomerase III family protein [Escherichia coli].	29.01	717	448	20	1	673	1	700	1e-61	230
rs:WP_003625660	DNA topoisomerase III [Lactobacillus helveticus].	28.06	613	413	13	3	592	4	611	1e-61	230
rs:WP_011222029	DNA topoisomerase [Lactobacillus plantarum].	29.34	610	387	15	3	581	4	600	1e-61	230
rs:WP_046648653	DNA topoisomerase I [Bacillus cereus].	27.72	707	456	20	3	675	5	690	1e-61	232
rs:WP_011187245	DNA topoisomerase III [Campylobacter jejuni].	29.10	725	436	23	1	669	1	703	1e-61	230
tr:A0A0A1S3R0_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.20	734	436	28	1	677	1	700	1e-61	230
rs:WP_032078168	DNA topoisomerase III [Clostridium drakei].	27.36	764	455	20	3	673	5	761	1e-61	231
rs:WP_038851175	DNA topoisomerase III, partial [Campylobacter coli].	28.97	725	437	23	1	669	1	703	1e-61	230
rs:WP_021580495	hypothetical protein [Escherichia coli].	28.45	717	452	19	1	673	1	700	1e-61	230
rs:WP_008028166	DNA topoisomerase III [Pseudomonas sp. GM60].	26.65	623	414	13	1	592	1	611	1e-61	229
rs:WP_042991347	DNA topoisomerase III, partial [Bifidobacterium adolescentis].	26.79	672	410	19	72	679	4	657	1e-61	229
tr:K5DE93_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKJ91283.1};	28.98	566	382	10	118	676	1	553	1e-61	227
rs:WP_047227795	DNA topoisomerase III [Pseudomonas brassicacearum].	27.05	610	399	15	1	578	1	596	1e-61	229
rs:WP_001235740	DNA topoisomerase III [Escherichia coli].	29.62	709	443	19	1	668	1	694	1e-61	230
rs:WP_007046111	DNA topoisomerase [Subdoligranulum variabile].	32.52	409	250	9	1	399	1	393	1e-61	225
rs:WP_021503224	DNA topoisomerase III family protein [Escherichia coli].	29.01	717	448	20	1	673	1	700	1e-61	230
rs:WP_021538564	hypothetical protein [Escherichia coli].	29.12	735	449	21	1	680	1	718	1e-61	230
rs:WP_032585756	DNA topoisomerase III [Campylobacter jejuni].	29.10	725	436	23	1	669	1	703	1e-61	230
rs:WP_028622141	DNA topoisomerase III [Pseudomonas sp. Ant30-3].	26.55	614	401	11	1	580	1	598	1e-61	228
rs:WP_023177191	DNA topoisomerase III [Carnobacterium sp. WN1359].	27.88	660	411	20	3	644	4	616	1e-61	229
rs:WP_002779644	MULTISPECIES: DNA topoisomerase III [Campylobacter].	29.24	725	435	23	1	669	1	703	1e-61	230
rs:WP_044816425	DNA topoisomerase III, partial [Escherichia coli].	30.93	540	338	15	100	608	6	541	1e-61	226
rs:WP_043019247	DNA topoisomerase III, partial [Campylobacter jejuni].	29.18	682	425	20	1	639	1	667	1e-61	229
rs:WP_012723395	DNA topoisomerase III [Pseudomonas fluorescens].	27.17	611	401	13	1	580	1	598	1e-61	228
rs:WP_038270228	hypothetical protein, partial [[Clostridium] clostridioforme].	29.90	602	370	17	105	683	1	573	1e-61	227
rs:WP_021128957	DNA topoisomerase [[Clostridium] sordellii].	28.07	734	437	28	1	677	1	700	1e-61	229
rs:WP_038114435	DNA topoisomerase [Veillonella sp. AS16].	28.55	634	392	16	1	581	1	626	1e-61	230
rs:WP_042533544	DNA topoisomerase [Oceanobacillus oncorhynchi].	29.35	719	455	21	1	679	3	708	2e-61	229
rs:WP_010649676	DNA topoisomerase [Oceanobacillus massiliensis].	29.50	722	452	25	1	680	1	707	2e-61	229
rs:WP_035528736	hypothetical protein, partial [Haliea salexigens].	26.60	624	408	15	1	581	1	617	2e-61	228
rs:WP_001401704	DNA topoisomerase III family protein [Escherichia coli].	29.12	735	449	21	1	680	1	718	2e-61	229
rs:WP_044798418	DNA topoisomerase I [Bacillus thuringiensis].	29.02	665	440	19	32	675	37	690	2e-61	231
rs:WP_034280392	conjugal transfer protein TraE, partial [Alkanindiges illinoisensis].	28.69	711	444	21	2	668	5	696	2e-61	229
tr:A0A0A8VTK4_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.07	734	437	28	1	677	1	700	2e-61	229
rs:WP_001235749	DNA topoisomerase III [Escherichia coli].	29.13	714	450	18	1	673	1	699	2e-61	229
rs:WP_025481001	DNA topoisomerase [Enterococcus faecium].	27.97	708	456	17	3	667	4	700	2e-61	230
rs:WP_029321244	DNA topoisomerase III, partial [Butyrivibrio sp. AE3004].	27.87	671	399	20	3	596	5	667	2e-61	229
rs:WP_045243737	DNA topoisomerase III [Campylobacter coli].	28.97	725	437	23	1	669	1	703	2e-61	230
rs:WP_042125997	DNA topoisomerase III [Pseudomonas japonica].	26.48	608	405	14	1	578	1	596	2e-61	228
rs:WP_039763141	DNA topoisomerase III [Pseudomonas fluorescens].	26.53	622	416	13	1	592	1	611	2e-61	228
rs:WP_035055399	DNA topoisomerase III [Carnobacterium pleistocenium].	28.32	625	387	17	3	611	4	583	2e-61	229
rs:WP_023156604	DNA topoisomerase [Escherichia coli].	29.13	714	450	18	1	673	1	699	2e-61	229
rs:WP_013725751	DNA topoisomerase III [Clostridium botulinum].	27.48	746	455	21	3	673	5	739	2e-61	230
tr:A0A0C7RDW4_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEQ13906.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEQ13906.1};	28.07	734	437	28	1	677	1	700	2e-61	229
rs:WP_013583068	DNA topoisomerase [Yersinia pestis].	27.11	723	464	18	1	679	1	704	2e-61	229
rs:WP_032593162	DNA topoisomerase III [Campylobacter jejuni].	29.10	725	436	23	1	669	1	703	2e-61	229
rs:WP_046797616	conjugal transfer protein TraE [Rhizobium sp. LC145].	27.51	658	409	16	2	614	5	639	2e-61	230
rs:WP_044927340	DNA topoisomerase, partial [Roseburia inulinivorans].	27.46	630	393	14	6	578	1	623	2e-61	228
rs:WP_011187227	cpp49 [Campylobacter coli].	28.97	725	437	23	1	669	1	703	2e-61	229
rs:WP_016095076	DNA topoisomerase 1 [Bacillus cereus].	28.61	671	435	18	32	675	37	690	2e-61	231
rs:WP_017184069	conjugal transfer protein TraE [Sphingobium xenophagum].	27.44	645	416	14	3	614	6	631	2e-61	229
tr:A0A0C7I5E1_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEO07878.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEO07878.1};	28.07	734	437	28	1	677	1	700	2e-61	229
rs:WP_011191426	DNA topoisomerase III [Yersinia pseudotuberculosis].	26.95	742	452	21	1	682	1	712	2e-61	229
rs:WP_001235767	DNA topoisomerase III [Escherichia coli].	29.13	714	450	18	1	673	1	699	2e-61	229
tr:A0A0C7LPY8_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEP45178.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEP45178.1};	28.07	734	437	28	1	677	1	700	2e-61	229
rs:WP_031554387	DNA topoisomerase III, partial [Oribacterium sp. FC2011].	27.87	671	380	18	2	580	3	661	2e-61	228
tr:A0A0E2SWY0_BACFG	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EXZ78927.1};	28.31	650	419	19	54	677	2	630	2e-61	228
rs:WP_002801286	DNA topoisomerase III, partial [Campylobacter coli].	30.15	650	401	19	1	612	1	635	2e-61	228
rs:WP_025380732	DNA topoisomerase III [Escherichia coli].	29.12	735	449	21	1	680	1	718	2e-61	229
rs:WP_034474891	DNA topoisomerase [Butyrivibrio proteoclasticus].	25.76	761	474	22	2	679	4	756	2e-61	233
tr:A0A0C7GCE7_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEN79521.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEN79521.1};	27.87	732	441	27	1	677	1	700	2e-61	229
rs:WP_041095836	topoisomerase I [Lactobacillus hokkaidonensis].	28.78	608	393	17	3	581	4	600	2e-61	229
rs:WP_010566039	DNA topoisomerase III [Pseudomonas extremaustralis].	27.17	611	401	12	1	580	1	598	2e-61	228
rs:WP_017143085	DNA topoisomerase I [Bacteroides finegoldii].	29.21	558	375	10	126	676	12	556	2e-61	226
tr:A0A0A1H2H0_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.78	608	393	17	3	581	6	602	2e-61	229
rs:WP_045057706	DNA topoisomerase III [Pseudomonas sp. ES3-33].	26.72	610	405	12	1	580	1	598	2e-61	228
rs:WP_002809261	DNA topoisomerase III, partial [Campylobacter coli].	30.00	650	402	19	1	612	1	635	2e-61	228
tr:A0A0C7S4V2_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEQ22916.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEQ22916.1};	28.07	734	437	28	1	677	1	700	2e-61	229
rs:WP_005540135	conjugal transfer protein TraE [Aggregatibacter actinomycetemcomitans].	27.25	756	458	23	1	682	1	738	2e-61	230
rs:WP_032242577	DNA topoisomerase III [Escherichia coli].	29.48	709	444	19	1	668	1	694	2e-61	229
rs:WP_041480830	DNA topoisomerase III [Pseudomonas sp. PTA1].	26.53	622	416	13	1	592	1	611	2e-61	228
rs:WP_034538462	DNA topoisomerase III [Carnobacterium inhibens].	27.73	660	412	20	3	644	4	616	2e-61	229
rs:WP_000520751	DNA topoisomerase I [Bacillus cereus].	27.68	672	440	19	32	675	37	690	2e-61	231
rs:WP_004574786	DNA topoisomerase [Pseudomonas putida].	27.90	724	449	24	3	675	5	706	2e-61	231
rs:WP_038612558	DNA topoisomerase III [Pseudomonas alkylphenolia].	26.77	609	406	11	1	580	1	598	2e-61	228
tr:A0A0C7RPC2_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEQ09394.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEQ09394.1};	28.07	734	437	28	1	677	1	700	2e-61	229
rs:WP_034292903	DNA topoisomerase III [Alysiella crassa].	28.38	733	434	24	3	682	5	699	2e-61	229
rs:WP_026013519	DNA topoisomerase III [Pseudomonas fluorescens].	27.17	611	401	12	1	580	1	598	2e-61	228
tr:A0A0C7HPT5_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEN96764.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEN96764.1};	28.07	734	437	28	1	677	1	700	2e-61	229
rs:WP_010272697	DNA topoisomerase III [Paenibacillus senegalensis].	29.06	678	404	27	3	632	4	652	2e-61	230
rs:WP_000520749	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	27.68	672	440	19	32	675	37	690	2e-61	231
rs:WP_015057151	DNA topoisomerase III [Escherichia coli].	28.71	735	452	21	1	680	1	718	2e-61	229
rs:WP_040177890	DNA topoisomerase III, partial [Klebsiella pneumoniae].	34.38	445	260	14	163	581	8	446	2e-61	224
rs:WP_024256650	DNA topoisomerase III [Escherichia coli].	29.06	709	447	19	1	668	1	694	2e-61	229
rs:WP_022045540	DNA topoisomerase [Roseburia sp. CAG:18].	25.90	753	469	20	3	679	5	744	2e-61	233
tr:B7ATA4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.02	671	379	21	3	580	9	668	2e-61	229
tr:A0A0C7T5M5_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEQ28293.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEQ28293.1};	28.07	734	437	28	1	677	1	700	2e-61	229
rs:WP_045147076	DNA topoisomerase III [Escherichia coli].	28.87	717	449	20	1	673	1	700	3e-61	229
tr:A0A0C7Q4Q1_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEP92298.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEP92298.1};	28.07	734	437	28	1	677	1	700	3e-61	229
rs:WP_038816692	DNA topoisomerase III [Campylobacter jejuni].	28.97	725	437	23	1	669	1	703	3e-61	229
rs:WP_001550443	DNA topoisomerase III family protein [Escherichia coli].	28.99	714	451	19	1	673	1	699	3e-61	229
rs:WP_038834218	DNA topoisomerase III [Campylobacter coli].	28.97	725	437	23	1	669	1	703	3e-61	229
rs:WP_016098187	DNA topoisomerase III [Bacillus cereus].	27.83	715	457	24	3	678	4	698	3e-61	229
rs:WP_000520748	DNA topoisomerase I [Bacillus cereus].	27.68	672	440	19	32	675	37	690	3e-61	231
rs:WP_003210143	DNA topoisomerase [Bacillus mycoides].	27.55	715	459	22	3	678	4	698	3e-61	229
rs:WP_044912868	DNA topoisomerase III [Butyrivibrio sp. WCE2006].	28.32	692	403	22	3	613	5	684	3e-61	228
rs:WP_002484856	DNA topoisomerase III [Staphylococcus epidermidis].	33.91	516	302	17	3	500	4	498	3e-61	224
rs:WP_005786941	DNA topoisomerase III [Pseudomonas synxantha].	27.05	610	403	12	1	580	1	598	3e-61	228
rs:WP_002839589	DNA topoisomerase III, partial [Campylobacter coli].	30.00	650	402	19	1	612	1	635	3e-61	227
rs:WP_019109223	MULTISPECIES: DNA topoisomerase III [Campylobacter].	28.97	725	437	23	1	669	1	703	3e-61	229
rs:WP_040893084	DNA topoisomerase III [[Bacteroides] pectinophilus].	28.02	671	379	21	3	580	5	664	3e-61	228
rs:WP_026345770	DNA topoisomerase III [Pseudomonas sp. 45MFCol3.1].	26.65	623	414	13	1	592	1	611	3e-61	228
rs:WP_030130788	DNA topoisomerase III [Pseudomonas sp. QTF5].	26.55	614	401	12	1	580	1	598	3e-61	228
rs:WP_027903059	DNA topoisomerase III [Pseudomonas sp. URMO17WK12:I3].	26.93	609	405	14	1	580	1	598	3e-61	228
tr:A0A0C7NNS0_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEP79536.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEP79536.1};	28.07	734	437	28	1	677	1	700	3e-61	229
rs:WP_000520746	DNA topoisomerase I [Bacillus cereus].	27.68	672	440	19	32	675	37	690	3e-61	231
rs:WP_000520747	DNA topoisomerase I [Bacillus cereus].	27.68	672	440	19	32	675	37	690	3e-61	231
rs:WP_002790206	DNA topoisomerase III, partial [Campylobacter coli].	29.91	652	400	20	1	612	1	635	3e-61	227
rs:WP_003332668	DNA topoisomerase [Bacillus azotoformans].	28.65	726	445	27	1	678	2	702	3e-61	229
rs:WP_001235764	DNA topoisomerase III [Escherichia coli].	29.12	735	449	21	1	680	1	718	3e-61	229
rs:WP_000520731	DNA topoisomerase I [Bacillus cereus].	28.08	666	445	17	32	675	37	690	3e-61	231
rs:WP_026510388	DNA topoisomerase III [Butyrivibrio sp. LC3010].	28.32	692	403	22	3	613	5	684	3e-61	228
rs:WP_021876076	DNA topoisomerase [Clostridium chauvoei].	29.13	635	381	19	3	580	5	627	3e-61	228
rs:WP_015058978	Topo3 [Escherichia coli].	28.99	714	451	18	1	673	1	699	3e-61	229
tr:A0A0C7R9A4_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEQ12311.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEQ12311.1};	28.01	732	440	27	1	677	1	700	3e-61	229
rs:WP_008521801	DNA topoisomerase III [Jonquetella anthropi].	28.87	613	384	15	1	575	1	599	3e-61	227
rs:WP_029321285	DNA topoisomerase [Bacillus sp. RP1137].	29.10	732	437	26	1	678	1	704	3e-61	229
rs:WP_003513145	DNA topoisomerase III [Ruminiclostridium thermocellum].	29.75	632	383	19	2	580	4	627	3e-61	228
tr:U3N979_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.51	488	312	12	1	471	1	473	3e-61	224
tr:C2XKX2_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.08	666	445	17	32	675	44	697	3e-61	231
rs:WP_004907636	hypothetical protein [Acinetobacter junii].	28.55	739	428	25	3	677	4	706	3e-61	230
rs:WP_042233258	DNA topoisomerase III, partial [Paenibacillus chitinolyticus].	28.41	616	380	22	3	577	4	599	3e-61	228
rs:WP_001235742	DNA topoisomerase III [Escherichia coli].	29.62	709	443	19	1	668	1	694	3e-61	229
rs:WP_017530498	DNA topoisomerase III [Pseudomonas fluorescens].	26.89	610	404	12	1	580	1	598	4e-61	227
rs:WP_001235738	DNA topoisomerase III [Escherichia coli].	28.84	704	455	16	1	668	1	694	4e-61	229
rs:WP_016278733	DNA topoisomerase III [Lachnospiraceae bacterium A4].	25.06	778	480	20	2	683	4	774	4e-61	233
rs:WP_003200140	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	26.48	608	405	12	1	578	1	596	4e-61	227
rs:WP_032325884	DNA topoisomerase III [Escherichia coli].	29.09	715	449	19	1	673	1	699	4e-61	228
rs:WP_022498679	DNA topoisomerase [Firmicutes bacterium CAG:95].	28.85	655	381	19	3	580	5	651	4e-61	228
rs:WP_004051183	DNA topoisomerase III [Lactobacillus murinus].	27.93	673	411	17	2	648	3	627	4e-61	228
tr:F3VI83_STREE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.94	442	255	11	1	431	1	416	4e-61	222
rs:WP_033552208	DNA topoisomerase III [Escherichia coli].	28.71	714	453	18	1	673	1	699	4e-61	228
tr:A4NVD0_HAEIF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.20	532	324	14	89	583	1	527	4e-61	225
tr:A0A0A8VZ19_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.79	734	439	27	1	677	1	700	4e-61	228
rs:WP_040126097	DNA topoisomerase III [Escherichia coli].	29.48	709	444	19	1	668	1	694	4e-61	228
rs:WP_001576902	DNA topoisomerase III [Escherichia coli].	28.99	714	451	18	1	673	1	699	4e-61	228
rs:WP_002826426	DNA topoisomerase III, partial [Campylobacter coli].	29.85	650	403	19	1	612	1	635	4e-61	227
rs:WP_045171904	DNA topoisomerase [Enterococcus faecium].	27.99	711	452	18	3	667	4	700	4e-61	229
rs:WP_036613568	DNA topoisomerase III, partial [Oribacterium sp. P6A1].	35.31	405	237	12	1	396	3	391	4e-61	221
rs:WP_025844504	DNA topoisomerase III, partial [Paenibacillus ehimensis].	29.66	617	374	20	3	577	4	602	4e-61	227
tr:W7ZEF8_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.56	653	410	21	2	627	4	633	4e-61	228
rs:WP_017172407	hypothetical protein [Xanthomonas axonopodis].	28.99	745	442	25	3	684	5	725	4e-61	230
rs:WP_002804385	DNA topoisomerase III, partial [Campylobacter coli].	30.15	650	401	19	1	612	1	635	4e-61	227
rs:WP_025693453	DNA topoisomerase III [Escherichia coli].	29.13	714	450	18	1	673	1	699	4e-61	228
rs:WP_021533550	hypothetical protein [Escherichia coli].	28.71	714	453	18	1	673	1	699	4e-61	228
rs:WP_034638379	DNA topoisomerase III, partial [Bacillus manliponensis].	31.24	541	318	15	1	507	1	521	5e-61	224
tr:M4JXQ1_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.81	579	379	11	31	578	9	579	5e-61	227
rs:WP_016234218	DNA topoisomerase III [Escherichia coli].	28.84	704	455	16	1	668	1	694	5e-61	228
rs:WP_043012959	DNA topoisomerase III [Campylobacter jejuni].	28.97	725	437	23	1	669	1	703	5e-61	228
rs:WP_033544695	DNA topoisomerase III [Escherichia coli].	28.98	735	450	21	1	680	1	718	5e-61	228
rs:WP_002139803	DNA topoisomerase I [Bacillus cereus].	28.43	714	443	25	3	675	5	691	5e-61	230
rs:WP_032595977	DNA topoisomerase III, partial [Campylobacter jejuni].	29.57	673	415	21	1	629	1	658	5e-61	227
rs:WP_027912566	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	26.32	608	406	12	1	578	1	596	5e-61	227
rs:WP_032587447	DNA topoisomerase III [Campylobacter jejuni].	28.97	725	437	23	1	669	1	703	5e-61	228
rs:WP_032600155	DNA topoisomerase III, partial [Campylobacter jejuni].	29.33	682	424	20	1	639	1	667	5e-61	227
rs:WP_002869583	DNA topoisomerase III [Campylobacter jejuni].	29.14	683	426	20	1	640	1	668	5e-61	228
rs:WP_025399361	DNA topoisomerase III [Campylobacter coli].	28.97	725	437	23	1	669	1	703	5e-61	228
rs:WP_045706786	DNA topoisomerase III [Desulfobulbaceae bacterium BRH_c16a].	27.92	720	442	24	3	675	6	695	5e-61	229
rs:WP_042827078	DNA topoisomerase [Xanthomonas axonopodis].	28.99	745	442	25	3	684	5	725	5e-61	229
rs:WP_022455370	DNA topoisomerase I [Parabacteroides sp. CAG:409].	30.47	512	312	12	1	489	12	502	5e-61	224
rs:WP_036781770	DNA topoisomerase III [Pontibacillus chungwhensis].	27.76	688	456	14	3	658	5	683	5e-61	228
rs:WP_033560648	DNA topoisomerase III [Escherichia coli].	29.27	714	449	18	1	673	1	699	5e-61	228
tr:S9PA36_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.82	660	393	19	1	590	1	640	5e-61	233
rs:WP_021801651	DNA topoisomerase III [Clostridium intestinale].	28.39	627	384	14	3	577	5	618	5e-61	227
rs:WP_017170432	hypothetical protein [Xanthomonas axonopodis].	28.99	745	442	25	3	684	5	725	5e-61	229
rs:WP_034288008	DNA topoisomerase III [Helicobacter sp. MIT 11-5569].	28.32	752	450	24	1	683	1	732	5e-61	228
rs:WP_034169408	DNA topoisomerase III [Escherichia coli].	28.84	735	451	21	1	680	1	718	5e-61	228
rs:WP_000520745	DNA topoisomerase I [Bacillus cereus].	27.42	671	443	17	32	675	37	690	5e-61	230
tr:A0A0C7JCB9_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEO26515.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEO26515.1};	28.07	734	437	28	1	677	1	700	5e-61	228
rs:WP_013692697	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	26.32	608	406	12	1	578	1	596	5e-61	227
rs:WP_012896713	DNA topoisomerase III [Staphylococcus aureus].	29.61	645	409	17	3	620	4	630	5e-61	228
rs:WP_029200156	DNA topoisomerase III [Oribacterium sp. NK2B42].	28.27	665	385	20	2	580	3	661	5e-61	227
rs:WP_042098135	DNA topoisomerase III [Escherichia coli].	29.27	714	449	18	1	673	1	699	6e-61	228
rs:WP_024235642	DNA topoisomerase III [Escherichia coli].	29.13	714	450	18	1	673	1	699	6e-61	228
rs:WP_001478770	DNA topoisomerase III family protein [Escherichia coli].	28.71	714	453	18	1	673	1	699	6e-61	228
rs:WP_020191335	hypothetical protein [Pseudomonas putida].	28.30	682	418	22	3	635	5	664	6e-61	229
rs:WP_008984953	DNA topoisomerase III [Alishewanella agri].	29.05	599	380	14	1	560	1	593	6e-61	227
rs:WP_023155063	DNA topoisomerase [Escherichia coli].	29.01	717	448	21	1	673	1	700	6e-61	228
rs:WP_024127756	DNA topoisomerase III [Escherichia coli].	28.99	714	451	18	1	673	1	699	6e-61	228
rs:WP_044722401	DNA topoisomerase III [Escherichia coli].	29.01	717	448	21	1	673	1	700	6e-61	228
rs:WP_045762245	DNA topoisomerase III [Xanthomonas albilineans].	27.33	611	409	14	1	587	1	600	6e-61	228
rs:WP_002842888	DNA topoisomerase III [Campylobacter coli].	30.14	657	392	21	1	612	1	635	6e-61	227
rs:WP_017755419	hypothetical protein [Bacillus sp. ZYK].	28.29	721	456	22	1	679	1	702	6e-61	228
rs:WP_031943130	DNA processing protein [uncultured bacterium].	27.51	658	409	17	2	614	5	639	6e-61	228
rs:WP_001505439	DNA topoisomerase III family protein [Escherichia coli].	29.41	714	448	19	1	673	1	699	6e-61	228
tr:A0A0C7IT59_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEO21894.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEO21894.1};	27.93	734	438	28	1	677	1	700	6e-61	228
rs:WP_031922615	DNA topoisomerase III [Staphylococcus aureus].	29.46	645	410	17	3	620	4	630	6e-61	228
rs:WP_021907748	DNA topoisomerase [Eubacterium sp. CAG:146].	27.54	719	465	17	2	680	3	705	6e-61	228
rs:WP_002822851	DNA topoisomerase III, partial [Campylobacter coli].	29.85	650	403	19	1	612	1	635	7e-61	226
rs:WP_026690239	DNA topoisomerase III [Bacillus aurantiacus].	28.53	722	435	25	1	664	1	699	7e-61	228
rs:WP_025481136	DNA topoisomerase [Enterococcus faecium].	27.99	711	452	18	3	667	4	700	7e-61	228
gp:CP002030_34	cpp49 [Campylobacter jejuni subsp. jejuni ICDCCJ07001]	29.33	682	424	20	1	639	1	667	7e-61	227
rs:WP_001235765	DNA topoisomerase III [Escherichia coli].	29.07	712	443	19	1	668	1	694	7e-61	228
rs:WP_021670479	DNA topoisomerase, partial [Prevotella sp. F0091].	30.35	603	384	16	85	673	32	612	7e-61	226
rs:WP_001401828	DNA topoisomerase III family protein [Escherichia coli].	28.71	714	453	18	1	673	1	699	7e-61	228
rs:WP_015391084	DNA topoisomerase 3 [Clostridium saccharoperbutylacetonicum].	28.03	735	444	24	2	680	3	708	7e-61	228
rs:WP_039240526	DNA topoisomerase III [Clostridium botulinum].	27.48	746	455	21	3	673	5	739	7e-61	228
rs:WP_001420449	DNA topoisomerase III family protein [Escherichia coli].	29.01	717	448	20	1	673	1	700	7e-61	228
tr:A0A0B0HJQ3_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.57	530	315	13	3	516	5	497	7e-61	223
rs:WP_042609385	DNA topoisomerase III [Pseudomonas fluorescens].	26.77	609	406	13	1	580	1	598	7e-61	226
rs:WP_043042072	DNA topoisomerase III [Pseudomonas fluorescens].	26.32	608	406	12	1	578	1	596	7e-61	226
rs:WP_047081943	DNA topoisomerase III [Escherichia coli].	29.38	708	445	18	1	668	1	693	7e-61	228
rs:WP_001235741	DNA topoisomerase III [Escherichia coli].	29.06	709	447	19	1	668	1	694	7e-61	228
rs:WP_021526210	hypothetical protein [Escherichia coli].	29.27	714	449	18	1	673	1	699	8e-61	228
rs:WP_039076293	DNA topoisomerase III [Bacillus sp. MSP13].	29.60	652	417	17	2	636	3	629	8e-61	227
rs:WP_022937740	DNA topoisomerase III [Dielma fastidiosa].	27.58	660	432	17	3	636	4	643	8e-61	228
rs:WP_044289457	MULTISPECIES: DNA topoisomerase III [Robinsoniella].	28.77	657	393	20	3	594	5	651	8e-61	227
rs:WP_032627286	DNA topoisomerase III [Pseudomonas syringae].	27.32	615	404	14	1	584	1	603	8e-61	226
rs:WP_031862612	DNA topoisomerase III, partial [Staphylococcus aureus].	29.46	645	410	17	3	620	4	630	8e-61	226
rs:WP_031861664	DNA topoisomerase III [Staphylococcus aureus].	29.61	645	409	17	3	620	4	630	8e-61	227
tr:E0RWM5_BUTPB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.76	761	474	22	2	679	4	756	8e-61	231
tr:G4L3K7_TETHN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.02	590	350	17	3	554	4	574	8e-61	225
rs:WP_038438416	DNA topoisomerase III [Salmonella enterica].	29.31	720	442	20	1	673	1	700	8e-61	228
rs:WP_022765397	DNA topoisomerase III [Butyrivibrio sp. XPD2006].	29.80	661	364	24	3	578	6	651	9e-61	227
rs:WP_002834103	DNA topoisomerase III, partial [Campylobacter coli].	29.85	650	403	19	1	612	1	635	9e-61	226
rs:WP_044797016	DNA topoisomerase I [Bacillus cereus].	27.78	666	447	19	32	675	37	690	9e-61	229
rs:WP_011205815	MULTISPECIES: DNA topoisomerase [Proteobacteria].	27.51	658	409	17	2	614	5	639	9e-61	228
rs:WP_001235747	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	29.13	714	450	18	1	673	1	699	9e-61	228
rs:WP_002369673	DNA topoisomerase [Enterococcus faecium].	27.68	708	458	17	3	667	4	700	9e-61	228
rs:WP_032490885	topoisomerase [Yersinia enterocolitica].	26.34	748	469	20	1	682	1	732	9e-61	228
tr:Q5NX65_AROAE	SubName: Full=TopA protein {ECO:0000313|EMBL:CAI10349.1};	26.32	608	399	15	1	581	1	586	9e-61	226
rs:WP_009644006	toprim domain protein, partial [Mogibacterium sp. CM50].	35.82	402	232	11	1	392	1	386	9e-61	219
rs:WP_001429160	DNA topoisomerase III family protein [Escherichia coli].	28.71	714	453	18	1	673	1	699	9e-61	227
rs:WP_043793203	DNA topoisomerase III, partial [Delftia tsuruhatensis].	28.79	660	393	21	68	666	16	659	9e-61	229
rs:WP_040072224	DNA topoisomerase III [Escherichia coli].	28.71	714	453	18	1	673	1	699	9e-61	227
rs:WP_002872081	DNA topoisomerase III, partial [Campylobacter jejuni].	29.85	650	403	19	1	612	1	635	1e-60	226
rs:WP_026520344	DNA topoisomerase III [Butyrivibrio sp. FCS006].	30.92	663	355	25	3	578	6	652	1e-60	227
rs:WP_001423372	DNA topoisomerase III family protein [Escherichia coli].	28.71	714	453	18	1	673	1	699	1e-60	227
rs:WP_001235746	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	29.13	714	450	18	1	673	1	699	1e-60	227
rs:WP_043431407	ATP-dependent DNA helicase RecQ [Cystobacter fuscus].	26.79	657	391	19	4	590	11	647	1e-60	232
rs:WP_021537783	hypothetical protein [Escherichia coli].	28.71	735	452	21	1	680	1	718	1e-60	227
rs:WP_034174036	DNA topoisomerase III [Escherichia coli].	29.42	724	453	21	1	681	1	709	1e-60	227
rs:WP_046932116	DNA topoisomerase III [Xanthomonas gardneri].	28.59	612	399	15	1	587	1	599	1e-60	228
rs:WP_039257512	DNA topoisomerase III [Clostridium botulinum].	27.35	746	456	21	3	673	5	739	1e-60	228
rs:WP_035021888	DNA topoisomerase III [Carnobacterium sp. WN1374].	27.36	625	393	15	3	611	4	583	1e-60	227
rs:WP_032195778	DNA topoisomerase III [Escherichia coli].	29.27	714	449	18	1	673	1	699	1e-60	227
rs:WP_010172260	DNA topoisomerase III [Pseudomonas sp. PAMC 25886].	27.23	617	404	13	1	587	1	602	1e-60	226
tr:E5B1P7_ERWAM	SubName: Full=K03169 DNA topoisomerase III {ECO:0000313|EMBL:CBX79398.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBX79398.1};	29.80	557	356	11	100	629	1	549	1e-60	224
rs:WP_021544332	hypothetical protein [Escherichia coli].	28.85	714	452	18	1	673	1	699	1e-60	227
rs:WP_039259014	DNA topoisomerase III [Clostridium botulinum].	27.35	746	456	21	3	673	5	739	1e-60	228
rs:WP_042068605	DNA topoisomerase III [Escherichia coli].	29.13	714	450	18	1	673	1	699	1e-60	227
tr:D2MXM3_CAMJU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EFC32963.1};	29.18	682	425	20	1	639	1	667	1e-60	228
tr:A0A085V3L4_PSESX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.24	624	401	14	1	590	1	605	1e-60	226
rs:WP_040084152	DNA topoisomerase III [Escherichia coli].	28.85	714	452	18	1	673	1	699	1e-60	227
rs:WP_010074359	DNA topoisomerase [Clostridium cellulovorans].	28.30	728	451	26	2	679	3	709	1e-60	227
rs:WP_001235755	DNA topoisomerase III [Escherichia coli].	29.13	714	450	18	1	673	1	699	1e-60	227
rs:WP_036822275	DNA topoisomerase III [Pontibacillus yanchengensis].	28.19	713	455	19	3	676	5	699	1e-60	227
rs:WP_000765167	DNA topoisomerase III [Escherichia coli].	28.98	735	450	21	1	680	1	718	1e-60	227
rs:WP_038994990	DNA topoisomerase III [Escherichia coli].	29.13	714	450	18	1	673	1	699	1e-60	227
rs:WP_021523567	hypothetical protein [Escherichia coli].	28.57	714	454	18	1	673	1	699	1e-60	227
rs:WP_036609206	DNA topoisomerase III [Oribacterium sp. P6A1].	27.90	656	388	19	3	580	4	652	1e-60	226
tr:K1YUA4_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.09	667	423	20	1	639	3	647	1e-60	228
rs:WP_001235753	DNA topoisomerase III [Salmonella enterica].	28.57	714	454	18	1	673	1	699	1e-60	227
rs:WP_031825561	DNA topoisomerase III, partial [Staphylococcus aureus].	29.46	645	410	17	3	620	4	630	1e-60	226
rs:WP_022784300	DNA topoisomerase III [Lachnospiraceae bacterium NK4A179].	27.52	654	389	20	3	578	6	652	1e-60	226
rs:WP_022361881	DNA topoisomerase [Bacteroides pectinophilus CAG:437].	27.91	670	381	21	3	580	5	664	1e-60	226
rs:WP_001567310	DNA topoisomerase III [Escherichia coli].	28.85	714	452	18	1	673	1	699	1e-60	227
rs:WP_043485858	hypothetical protein, partial [Holophaga foetida].	27.87	628	390	20	1	581	3	614	2e-60	225
rs:WP_021526654	hypothetical protein [Escherichia coli].	28.85	714	452	18	1	673	1	699	2e-60	227
tr:A0A0E1ZME0_CAMJU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EIB53379.1}; Flags: Fragment;	29.85	650	403	19	1	612	1	635	2e-60	225
rs:WP_002467740	DNA topoisomerase III [Staphylococcus epidermidis].	33.72	516	303	17	3	500	4	498	2e-60	222
tr:F0BTR5_9XANT	SubName: Full=Topoisomerase IA {ECO:0000313|EMBL:EGD13677.1}; Flags: Fragment;	27.57	613	404	14	1	587	1	599	2e-60	226
rs:WP_013792850	DNA topoisomerase III [Pseudomonas fulva].	26.69	607	405	12	1	578	1	596	2e-60	226
rs:WP_002305772	DNA topoisomerase [Enterococcus faecium].	27.40	708	460	17	3	667	4	700	2e-60	227
rs:WP_025370412	hypothetical protein [Campylobacter fetus].	29.59	686	412	21	1	640	1	661	2e-60	226
tr:A0A0C7H255_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEN88271.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEN88271.1};	28.07	734	437	28	1	677	1	700	2e-60	227
rs:WP_018929752	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	26.60	624	413	13	1	592	1	611	2e-60	225
rs:WP_033837181	MULTISPECIES: DNA topoisomerase III [Xanthomonas].	27.04	699	452	18	1	658	1	682	2e-60	227
rs:WP_001235744	DNA topoisomerase III [Salmonella enterica].	28.71	714	453	18	1	673	1	699	2e-60	226
rs:WP_042106000	DNA topoisomerase III [Escherichia coli].	28.98	735	450	21	1	680	1	718	2e-60	227
rs:WP_015059104	DNA topoisomerase III [Escherichia coli].	29.13	714	450	18	1	673	1	699	2e-60	226
rs:WP_001235761	DNA topoisomerase III [Escherichia coli].	28.51	712	447	18	1	668	1	694	2e-60	226
rs:WP_022004444	DNA topoisomerase III [Firmicutes bacterium CAG:194].	28.53	645	388	18	2	578	4	643	2e-60	226
rs:WP_031882778	DNA topoisomerase III, partial [Staphylococcus aureus].	29.46	645	410	17	3	620	4	630	2e-60	226
rs:WP_031792597	DNA topoisomerase III [Staphylococcus aureus].	29.46	645	410	17	3	620	4	630	2e-60	226
rs:WP_031876719	DNA topoisomerase III [Staphylococcus aureus].	29.46	645	410	17	3	620	4	630	2e-60	226
rs:WP_047209149	DNA topoisomerase III [Staphylococcus aureus].	29.46	645	410	17	3	620	4	630	2e-60	226
rs:WP_044906266	hypothetical protein, partial [Lachnospiraceae bacterium MC2017].	27.38	672	390	19	3	589	12	670	2e-60	226
rs:WP_010459568	DNA topoisomerase III [Pseudomonas mandelii].	26.39	610	407	12	1	580	1	598	2e-60	225
rs:WP_031908286	DNA topoisomerase III, partial [Staphylococcus aureus].	29.39	677	413	21	37	673	28	679	2e-60	226
rs:WP_042512886	DNA topoisomerase [Bacillus cereus].	27.41	715	460	23	3	678	4	698	2e-60	226
rs:WP_001235743	DNA topoisomerase III [Escherichia coli].	28.85	714	452	18	1	673	1	699	2e-60	226
rs:WP_044982516	hypothetical protein, partial [Lachnospiraceae bacterium NK4A144].	27.87	671	385	20	3	589	12	667	2e-60	226
rs:WP_010714548	MULTISPECIES: DNA topoisomerase III, partial [Bacilli].	29.46	645	410	17	3	620	4	630	2e-60	226
rs:WP_001235756	DNA topoisomerase III [Escherichia coli].	28.85	714	452	18	1	673	1	699	2e-60	226
rs:WP_044099716	DNA topoisomerase III [Xanthomonas citri].	27.04	699	452	18	1	658	1	682	2e-60	226
rs:WP_001094109	MULTISPECIES: DNA topoisomerase III [Bacilli].	29.46	645	410	17	3	620	4	630	2e-60	226
rs:WP_033804686	DNA topoisomerase III [Escherichia coli].	28.85	714	452	18	1	673	1	699	2e-60	226
rs:WP_016169468	DNA topoisomerase III [Lachnospiraceae bacterium 10-1].	29.74	649	375	21	3	580	5	643	2e-60	226
rs:WP_046424380	DNA topoisomerase III [Escherichia coli].	28.98	735	450	21	1	680	1	718	2e-60	226
rs:WP_042743132	DNA topoisomerase III [Staphylococcus aureus].	29.46	645	410	17	3	620	4	630	2e-60	226
rs:WP_012291470	topoisomerase IA [Escherichia coli].	28.71	714	453	18	1	673	1	699	2e-60	226
rs:WP_026522671	DNA topoisomerase III [Butyrivibrio sp. VCB2001].	30.62	663	357	24	3	578	6	652	2e-60	226
rs:WP_032285169	DNA topoisomerase III [Escherichia coli].	28.71	735	452	21	1	680	1	718	2e-60	226
rs:WP_022056443	DNA topoisomerase III [Clostridium sp. CAG:167].	29.59	659	367	20	2	581	4	644	2e-60	226
rs:WP_016770543	DNA topoisomerase [Salmonella enterica].	28.85	714	452	18	1	673	1	699	2e-60	226
rs:WP_002314426	DNA topoisomerase [Enterococcus faecium].	27.85	711	453	18	3	667	4	700	3e-60	226
rs:WP_012662275	DNA topoisomerase III [Campylobacter lari].	27.96	683	443	17	1	642	1	675	3e-60	225
rs:WP_001235751	DNA topoisomerase III [Escherichia coli].	28.71	714	453	18	1	673	1	699	3e-60	226
rs:WP_001503703	DNA topoisomerase III family protein, partial [Escherichia coli].	28.95	708	447	19	1	667	1	693	3e-60	226
rs:WP_029397051	DNA topoisomerase III [Escherichia coli].	28.87	724	457	20	1	681	1	709	3e-60	226
rs:WP_027866328	hypothetical protein [Massilia alkalitolerans].	26.82	701	432	22	3	650	5	677	3e-60	227
rs:WP_025481655	DNA topoisomerase [Enterococcus faecium].	27.82	708	457	17	3	667	4	700	3e-60	226
rs:WP_031942376	DNA topoisomerase III [Escherichia coli].	28.71	714	453	18	1	673	1	699	3e-60	226
rs:WP_046232591	DNA topoisomerase III [Paenibacillus algorifonticola].	29.90	612	378	17	3	577	4	601	3e-60	227
rs:WP_032119137	DNA topoisomerase III [Clostridium sp. CL-2].	29.26	639	374	20	3	580	5	626	3e-60	225
rs:WP_005933789	DNA topoisomerase III [Faecalibacterium prausnitzii].	32.11	545	332	15	152	673	15	544	3e-60	223
rs:WP_028545467	DNA topoisomerase III [Paenibacillus taiwanensis].	27.64	626	381	19	3	577	10	614	3e-60	227
rs:WP_012263515	TrsI [Staphylococcus aureus].	29.61	645	409	17	3	620	4	630	3e-60	226
rs:WP_045216857	hypothetical protein, partial [Desulfobulbus alkaliphilus].	29.13	611	373	20	3	574	7	596	3e-60	224
rs:WP_031859997	DNA topoisomerase III [Staphylococcus aureus].	29.46	645	410	17	3	620	4	630	3e-60	226
rs:WP_001235758	DNA topoisomerase III [Escherichia coli].	28.75	713	454	17	1	673	1	699	3e-60	226
tr:X4BAN5_SALEN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	31.31	511	308	19	1	479	1	500	3e-60	221
rs:WP_012514069	DNA topoisomerase III [Hydrogenobaculum sp. Y04AAS1].	29.39	718	358	24	2	615	3	675	3e-60	226
rs:WP_025577921	DNA topoisomerase III [Blautia wexlerae].	34.72	386	223	11	1	376	1	367	3e-60	221
rs:WP_032274624	DNA topoisomerase III [Escherichia coli].	28.84	735	451	21	1	680	1	718	3e-60	226
rs:WP_000520750	DNA topoisomerase I [Bacillus thuringiensis].	27.38	672	442	19	32	675	37	690	3e-60	228
rs:WP_034288249	DNA topoisomerase [Bacillus sp. 72].	28.75	720	451	24	3	678	5	706	3e-60	226
rs:WP_001235745	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	28.71	714	453	18	1	673	1	699	3e-60	226
rs:WP_040955857	DNA topoisomerase [Virgibacillus sp. SK37].	27.89	717	461	21	1	678	1	700	3e-60	226
rs:WP_032346759	DNA topoisomerase III [Escherichia coli].	28.57	714	454	18	1	673	1	699	3e-60	226
tr:S4E1Q5_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.82	708	457	17	3	667	5	701	4e-60	226
rs:WP_001436419	DNA topoisomerase III family protein [Escherichia coli].	28.85	714	452	19	1	673	1	699	4e-60	226
rs:WP_033518198	DNA topoisomerase III, partial [Bifidobacterium cuniculi].	25.82	705	451	21	32	684	28	712	4e-60	226
rs:WP_034132827	DNA topoisomerase [Peptococcaceae bacterium BICA1-8].	29.39	643	394	17	2	591	4	639	4e-60	224
rs:WP_027446336	DNA topoisomerase III [Pontibacillus marinus].	27.71	700	439	17	3	658	5	681	4e-60	226
rs:WP_013056649	DNA topoisomerase [Bacillus megaterium].	28.96	732	438	26	1	678	1	704	4e-60	226
rs:WP_047090416	DNA topoisomerase III [Escherichia coli].	29.27	714	449	19	1	673	1	699	4e-60	226
rs:WP_001565875	DNA topoisomerase III [Escherichia coli].	29.13	714	450	18	1	673	1	699	4e-60	226
rs:WP_021534058	hypothetical protein [Escherichia coli].	28.57	714	454	18	1	673	1	699	4e-60	226
rs:WP_001482238	DNA topoisomerase III family protein [Escherichia coli].	28.57	714	454	18	1	673	1	699	4e-60	226
rs:WP_016731587	MULTISPECIES: DNA topoisomerase [Enterobacteriaceae].	28.71	714	453	18	1	673	1	699	4e-60	226
rs:WP_022123622	DNA topoisomerase [Clostridium sp. CAG:510].	25.63	749	478	19	3	679	5	746	4e-60	229
rs:WP_015844258	DNA topoisomerase III [Paenibacillus sp. JDR-2].	30.41	615	372	18	3	577	4	602	4e-60	226
rs:WP_023971603	DNA topoisomerase III, partial [Salmonella enterica].	31.37	510	307	19	1	478	1	499	4e-60	221
rs:WP_042100636	DNA topoisomerase III [Escherichia coli].	28.71	714	453	18	1	673	1	699	4e-60	226
rs:WP_028408833	DNA topoisomerase [Bacillus sp. 171095_106].	28.83	732	439	26	1	678	1	704	4e-60	226
rs:WP_009432418	DNA topoisomerase, partial [Porphyromonas sp. oral taxon 279].	30.77	598	368	18	95	673	3	573	4e-60	223
rs:WP_024013263	DNA topoisomerase III [Pseudomonas moraviensis].	26.48	623	415	13	1	592	1	611	4e-60	224
rs:WP_001235750	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	28.71	714	453	18	1	673	1	699	4e-60	226
rs:WP_025025884	DNA topoisomerase III [Bacillus mannanilyticus].	29.11	718	404	23	1	636	1	695	4e-60	226
rs:WP_044344485	DNA topoisomerase III [Escherichia coli].	28.71	714	453	18	1	673	1	699	4e-60	226
rs:WP_003562019	DNA topoisomerase III family protein [Escherichia coli].	29.13	714	450	18	1	673	1	699	4e-60	226
rs:WP_026694892	DNA topoisomerase [Bacillus kribbensis].	29.07	719	451	25	1	678	2	702	4e-60	225
rs:WP_026944559	DNA topoisomerase III [Helicobacter rodentium].	28.20	727	444	22	1	669	1	707	4e-60	226
rs:WP_032180613	DNA topoisomerase III [Escherichia coli].	29.13	714	450	18	1	673	1	699	5e-60	225
rs:WP_026513782	DNA topoisomerase III [Butyrivibrio sp. LB2008].	29.77	655	378	22	2	580	4	652	5e-60	225
rs:WP_032302216	DNA topoisomerase III [Escherichia coli].	29.21	712	441	20	1	668	1	693	5e-60	225
rs:WP_008592302	DNA topoisomerase III [Salimicrobium sp. MJ3].	27.02	718	454	19	3	676	5	696	5e-60	225
rs:WP_010691817	DNA topoisomerase III [Treponema denticola].	29.51	715	420	23	3	680	4	671	5e-60	225
rs:WP_025692485	hypothetical protein, partial [Paenibacillus zanthoxyli].	33.90	413	248	11	3	401	4	405	5e-60	218
rs:WP_036685684	DNA topoisomerase III [Paenibacillus sp. MSt1].	29.59	615	377	20	3	577	4	602	5e-60	226
rs:WP_043291748	hypothetical protein, partial [Burkholderia vietnamiensis].	27.08	624	402	14	2	581	3	617	5e-60	224
rs:WP_023225984	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	28.84	735	451	21	1	680	1	718	5e-60	225
rs:WP_040118351	DNA topoisomerase III [Pectobacterium atrosepticum].	26.21	744	475	20	1	682	1	732	5e-60	226
rs:WP_001235748	DNA topoisomerase III [Escherichia coli].	28.36	730	466	17	1	683	1	720	5e-60	225
rs:WP_020289917	DNA topoisomerase III [Pseudomonas sp. CFII64].	27.08	624	402	14	1	590	1	605	5e-60	224
rs:WP_024234184	DNA topoisomerase III [Escherichia coli].	28.71	714	453	18	1	673	1	699	5e-60	225
rs:WP_022638687	topoisomerase IA [Lactobacillus plantarum].	28.73	724	448	23	3	676	4	709	5e-60	225
rs:WP_029473397	DNA topoisomerase III [Clostridiales bacterium VE202-08].	27.42	660	433	17	3	636	4	643	5e-60	225
rs:WP_001235752	DNA topoisomerase III [Salmonella enterica].	28.43	714	455	18	1	673	1	699	5e-60	225
tr:W4V045_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE86442.1};	30.88	612	390	22	85	680	2	596	5e-60	223
rs:WP_039730506	DNA topoisomerase, partial [Enterococcus mundtii].	29.39	643	408	16	68	673	1	634	6e-60	224
rs:WP_033873156	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	28.78	556	359	13	1	527	1	548	6e-60	222
rs:WP_003600531	DNA topoisomerase III, partial [Lactobacillus casei].	29.35	569	363	15	41	581	1	558	6e-60	224
rs:WP_034638122	DNA topoisomerase [Bacillus manliponensis].	27.41	715	460	23	3	678	4	698	6e-60	225
rs:WP_018755653	hypothetical protein [Paenibacillus terrigena].	28.32	731	424	24	3	650	4	717	6e-60	226
rs:WP_016628767	DNA topoisomerase [Enterococcus faecium].	27.71	711	454	18	3	667	4	700	6e-60	225
rs:WP_035197261	DNA topoisomerase [Bacillus azotoformans].	28.65	726	445	27	1	678	2	702	6e-60	225
rs:WP_032181595	DNA topoisomerase III [Escherichia coli].	28.71	714	453	18	1	673	1	699	6e-60	225
rs:WP_025477545	DNA topoisomerase [Enterococcus faecium].	27.71	711	454	18	3	667	4	700	6e-60	225
rs:WP_012477155	DNA topoisomerase III [Salmonella enterica].	28.57	714	454	18	1	673	1	699	6e-60	225
rs:WP_033560771	DNA topoisomerase III [Escherichia coli].	28.05	713	452	19	5	673	1	696	6e-60	225
tr:D4QPS7_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.71	711	454	18	3	667	5	701	6e-60	225
rs:WP_022780297	DNA topoisomerase III [Lachnospiraceae bacterium NK4A136].	29.65	661	370	24	3	578	5	655	6e-60	224
rs:WP_031622287	DNA topoisomerase III [Salmonella enterica].	28.57	714	454	18	1	673	1	699	6e-60	225
rs:WP_017513957	DNA topoisomerase III, partial [beta proteobacterium FWI2].	29.34	542	344	14	1	512	1	533	7e-60	221
rs:WP_025477734	DNA topoisomerase [Enterococcus faecium].	27.71	711	454	18	3	667	4	700	7e-60	225
rs:WP_010494009	DNA topoisomerase III, partial [Paenibacillus elgii].	29.01	617	378	19	3	577	4	602	7e-60	223
rs:WP_024720786	DNA topoisomerase III [Clostridiales bacterium VE202-01].	33.96	424	252	10	1	413	1	407	7e-60	220
rs:WP_027109670	DNA topoisomerase III [Lachnospiraceae bacterium NC2008].	29.76	662	368	25	3	578	5	655	7e-60	224
rs:WP_015058228	DNA topoisomerase III [Escherichia coli].	28.71	714	453	18	1	673	1	699	7e-60	225
tr:T0XPW2_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.40	534	344	14	100	611	1	523	8e-60	223
rs:WP_032331421	DNA topoisomerase III [Escherichia coli].	28.71	714	453	18	1	673	1	699	8e-60	225
rs:WP_016112277	DNA topoisomerase 1 [Bacillus cereus].	27.02	707	457	19	3	673	5	688	8e-60	226
rs:WP_016247728	DNA topoisomerase III [Escherichia coli].	28.57	714	454	18	1	673	1	699	8e-60	225
tr:A0A087AVV4_9BIFI	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:KFI62904.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KFI62904.1};	25.82	705	451	21	32	684	28	712	8e-60	225
tr:A0A0D0PZV8_9BACI	SubName: Full=Contig8, whole genome shotgun sequence {ECO:0000313|EMBL:KIQ91353.1};	26.78	717	458	16	1	676	1	691	8e-60	224
rs:WP_032341387	DNA topoisomerase III [Escherichia coli].	29.65	715	435	22	1	668	1	694	9e-60	225
rs:WP_008687136	DNA topoisomerase III [Eubacterium sp. 3_1_31].	28.31	703	454	20	3	667	4	694	9e-60	224
rs:WP_001714225	DNA topoisomerase III [Salmonella enterica].	28.45	717	451	19	1	673	1	699	9e-60	224
rs:WP_018395281	DNA topoisomerase [Bacillus sp. 37MA].	28.61	720	452	24	3	678	5	706	9e-60	224
rs:WP_001235762	DNA topoisomerase III [Escherichia coli].	28.93	719	445	20	1	673	1	699	9e-60	224
rs:WP_036803215	hypothetical protein [Pontibacillus halophilus].	27.65	680	429	21	46	681	36	696	9e-60	224
rs:WP_001694195	DNA topoisomerase III family protein [Escherichia coli].	28.57	714	454	18	1	673	1	699	9e-60	224
rs:WP_001235760	DNA topoisomerase III [Escherichia coli].	28.99	714	451	18	1	673	1	699	1e-59	224
rs:WP_032904947	DNA topoisomerase III [Yersinia enterocolitica].	28.99	714	451	18	1	673	1	699	1e-59	224
rs:WP_043482912	hypothetical protein, partial [Geothrix fermentans].	29.23	626	379	21	1	578	1	610	1e-59	223
rs:WP_033797970	hypothetical protein [Bacillus mycoides].	26.49	721	462	18	1	680	1	694	1e-59	224
rs:WP_041668451	DNA topoisomerase III, partial [Ralstonia pickettii].	27.62	554	366	14	1	527	1	546	1e-59	221
tr:R9KJT4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.55	772	457	23	2	677	4	761	1e-59	226
rs:WP_002375953	DNA topoisomerase [Enterococcus faecium].	27.71	711	454	18	3	667	4	700	1e-59	224
rs:WP_016486988	MULTISPECIES: hypothetical protein [Pseudomonas putida group].	27.43	711	444	22	3	663	5	693	1e-59	226
rs:WP_000294907	DNA topoisomerase III, partial [Salmonella enterica].	33.26	445	269	12	161	581	11	451	1e-59	220
rs:WP_029276362	MULTISPECIES: DNA topoisomerase III [Carnobacterium].	27.93	623	392	17	3	611	4	583	1e-59	224
rs:WP_033918726	DNA topoisomerase, partial [Enterococcus faecalis].	30.96	575	342	16	3	541	4	559	1e-59	221
rs:WP_045488834	DNA topoisomerase [Bacillus sp. TS-2].	27.66	723	457	24	1	679	1	701	1e-59	224
rs:WP_029838760	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	29.31	539	342	12	2	508	3	534	1e-59	221
rs:WP_002135700	DNA topoisomerase [Bacillus cereus].	27.41	715	460	23	3	678	4	698	1e-59	224
rs:WP_032702136	DNA topoisomerase III, partial [Campylobacter coli].	30.82	610	376	17	1	574	1	600	1e-59	223
rs:WP_038592879	DNA topoisomerase III [Paenibacillus sp. FSL H7-0357].	28.48	618	375	21	3	577	4	597	1e-59	225
rs:WP_035149399	DNA topoisomerase III [Clostridium tetanomorphum].	27.97	765	445	21	3	673	5	757	1e-59	225
rs:WP_036705368	DNA topoisomerase III, partial [Paenibacillus graminis].	28.71	613	379	22	3	577	4	596	1e-59	223
rs:WP_016775107	DNA topoisomerase III, partial [Pseudomonas sp. R62].	26.44	609	408	12	1	580	1	598	1e-59	222
rs:WP_039052484	DNA topoisomerase III [Escherichia coli].	28.93	719	445	20	1	673	1	699	1e-59	224
rs:WP_044074388	DNA topoisomerase III [Escherichia coli].	28.57	714	454	18	1	673	1	699	1e-59	224
rs:WP_008979388	DNA topoisomerase III [Erysipelotrichaceae bacterium 5_2_54FAA].	28.31	703	454	20	3	667	4	694	1e-59	224
rs:WP_009672854	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	28.41	616	380	22	3	577	4	599	1e-59	225
rs:WP_001556719	DNA topoisomerase III [Escherichia coli].	28.57	714	454	18	1	673	1	699	1e-59	224
rs:WP_031390120	DNA topoisomerase III [Clostridium sp. KNHs209].	27.67	683	402	20	3	599	5	681	1e-59	224
tr:A4VNK8_PSEU5	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.62	571	383	11	41	581	3	567	1e-59	222
rs:WP_022036564	hypothetical protein [Roseburia sp. CAG:50].	29.56	653	369	22	3	579	5	642	1e-59	223
rs:WP_025479250	DNA topoisomerase [Enterococcus faecium].	27.71	711	454	18	3	667	4	700	1e-59	224
rs:WP_043712494	ATP-dependent DNA helicase RecQ, partial [Myxococcus fulvus].	28.11	594	364	16	46	578	1	592	1e-59	229
rs:WP_032597331	DNA topoisomerase III, partial [Campylobacter jejuni].	30.66	610	377	17	1	574	1	600	1e-59	223
rs:WP_023383812	DNA topoisomerase [Pseudomonas sp. VLB120].	27.75	710	443	22	3	663	5	693	1e-59	226
rs:WP_036972697	DNA topoisomerase III, partial [Providencia alcalifaciens].	33.90	472	266	17	140	581	50	505	1e-59	221
rs:WP_041592301	DNA topoisomerase III [Terribacillus aidingensis].	29.83	694	423	23	3	667	4	662	1e-59	223
rs:WP_034219466	DNA topoisomerase, partial [Lachnospiraceae bacterium AC2014].	28.26	644	386	19	2	579	4	637	1e-59	223
rs:WP_021528064	hypothetical protein [Escherichia coli].	28.95	715	450	19	1	673	1	699	1e-59	224
rs:WP_012655857	hypothetical protein [Macrococcus caseolyticus].	29.63	702	408	25	3	648	4	675	1e-59	224
rs:WP_022312971	DNA topoisomerase [Clostridium sp. CAG:91].	28.88	658	375	22	3	578	5	651	1e-59	224
rs:WP_041992809	DNA topoisomerase I, partial [Capnocytophaga cynodegmi].	29.96	554	350	14	1	533	1	537	1e-59	221
tr:F0HU31_LACDL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.92	574	347	11	3	538	4	554	1e-59	221
rs:WP_040427949	DNA topoisomerase III, partial [Acetivibrio cellulolyticus].	30.77	507	326	11	3	495	5	500	1e-59	219
rs:WP_022769064	DNA topoisomerase III [Butyrivibrio sp. NC2007].	30.62	663	357	25	3	578	6	652	1e-59	224
rs:WP_034145118	DNA topoisomerase III [Desulfosporosinus sp. BICA1-9].	29.70	633	380	16	3	581	5	626	1e-59	225
rs:WP_044546247	DNA topoisomerase I, partial [Parabacteroides distasonis].	31.56	564	341	19	1	533	1	550	1e-59	221
rs:WP_046598252	DNA topoisomerase III [Salmonella enterica].	28.95	715	450	19	1	673	1	699	1e-59	224
rs:WP_025480102	DNA topoisomerase [Enterococcus faecium].	27.71	711	454	18	3	667	4	700	1e-59	224
rs:WP_025480081	DNA topoisomerase [Enterococcus faecium].	27.71	711	454	18	3	667	4	700	2e-59	224
rs:WP_000520733	DNA topoisomerase I [Bacillus thuringiensis].	26.89	714	461	21	3	679	5	694	2e-59	226
rs:WP_021515666	hypothetical protein [Escherichia coli].	28.57	714	454	18	1	673	1	699	2e-59	224
rs:WP_002325542	DNA topoisomerase III [Enterococcus faecium].	27.71	711	454	18	3	667	5	701	2e-59	224
tr:A8U7S1_9LACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.93	623	392	17	3	611	14	593	2e-59	224
rs:WP_044923851	DNA topoisomerase III [Anaerostipes hadrus].	28.86	641	379	20	3	580	4	630	2e-59	223
rs:WP_006573547	hypothetical protein [Pseudoflavonifractor capillosus].	32.52	409	250	9	1	399	1	393	2e-59	219
rs:WP_043933664	DNA topoisomerase [Bacillus sp. EB01].	27.41	726	461	24	2	681	3	708	2e-59	224
rs:WP_023152731	DNA topoisomerase [Eubacterium brachy].	28.07	748	449	26	2	679	3	731	2e-59	224
rs:WP_001419801	DNA topoisomerase III family protein [Escherichia coli].	28.45	717	451	20	1	673	1	699	2e-59	224
rs:WP_044599622	DNA topoisomerase III [Campylobacter peloridis].	28.84	690	428	20	1	642	1	675	2e-59	223
rs:WP_029812642	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	29.44	540	340	13	2	508	3	534	2e-59	220
rs:WP_041030302	DNA topoisomerase III, partial [Salmonella enterica].	33.26	445	269	12	161	581	25	465	2e-59	219
rs:WP_012908954	DNA topoisomerase III [Citrobacter rodentium].	28.61	713	455	17	1	673	1	699	2e-59	224
tr:R3KM90_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.71	711	454	18	3	667	5	701	2e-59	224
rs:WP_001675950	DNA topoisomerase III [Salmonella enterica].	28.43	714	455	18	1	673	1	699	2e-59	224
tr:A0A0C7KFB3_XANCE	SubName: Full=TopB protein {ECO:0000313|EMBL:CEO96463.1};	27.12	612	408	14	1	587	1	599	2e-59	224
rs:WP_040012585	DNA topoisomerase, partial [Peptostreptococcaceae bacterium CM5].	33.13	483	283	13	2	472	4	458	2e-59	218
rs:WP_042513583	DNA topoisomerase III, partial [Bacillus cereus].	30.74	527	339	12	1	507	1	521	2e-59	219
tr:R3HW91_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.54	708	459	17	3	667	5	701	2e-59	224
rs:WP_043533225	DNA topoisomerase III [Klebsiella pneumoniae].	29.12	735	444	22	1	680	1	713	2e-59	223
rs:WP_046597968	DNA topoisomerase III [Salmonella enterica].	29.07	719	444	20	1	673	1	699	2e-59	223
rs:WP_006861796	DNA topoisomerase III [Marvinbryantia formatexigens].	28.21	631	393	16	3	579	5	629	2e-59	223
rs:WP_036573498	DNA topoisomerase [Oceanobacillus picturae].	28.83	725	453	24	1	681	1	706	2e-59	223
rs:WP_022325293	DNA topoisomerase [Clostridium sp. CAG:798].	29.07	578	350	12	3	531	4	570	2e-59	221
rs:WP_034898779	DNA topoisomerase III [Erwinia typographi].	27.16	740	460	23	1	676	1	725	2e-59	224
rs:WP_025259685	DNA topoisomerase III [Pseudomonas cichorii].	27.18	618	403	15	1	585	1	604	2e-59	222
rs:WP_019910740	DNA topoisomerase III [Paenibacillus sp. HW567].	29.27	615	374	23	3	577	4	597	2e-59	224
rs:WP_001677783	DNA topoisomerase III family protein [Escherichia coli].	28.45	717	451	20	1	673	1	699	3e-59	223
gpu:CP009300_2741	DNA topoisomerase III family protein [Bacillus cereus D17]	30.74	527	339	12	1	507	1	521	3e-59	219
tr:W7ZEP5_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.12	690	451	18	30	683	17	697	3e-59	223
rs:WP_025983593	DNA topoisomerase III [Xanthomonas axonopodis].	27.61	612	405	15	1	587	1	599	3e-59	223
tr:G9XCL0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.06	484	284	13	2	473	4	459	3e-59	218
rs:WP_021740058	DNA topoisomerase [Eubacterium ramulus].	29.40	653	370	22	3	579	5	642	3e-59	223
rs:WP_009264837	DNA topoisomerase III [Lachnospiraceae bacterium 5_1_63FAA].	29.02	641	378	22	3	580	4	630	3e-59	222
rs:WP_001235754	DNA topoisomerase III [Salmonella enterica].	28.99	714	451	18	1	673	1	699	3e-59	223
rs:WP_009203366	DNA topoisomerase III [Anaerostipes hadrus].	28.71	641	380	20	3	580	4	630	3e-59	222
rs:WP_045227513	DNA topoisomerase III, partial [Escherichia coli].	33.03	445	270	12	161	581	1	441	3e-59	218
tr:V1S057_SALET	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.18	449	272	12	157	581	30	474	3e-59	219
rs:WP_039836735	DNA topoisomerase III, partial [Paenibacillus sonchi].	28.71	613	379	22	3	577	4	596	3e-59	222
rs:WP_022744481	DNA topoisomerase 3 [Clostridium saccharobutylicum].	27.85	736	441	24	2	679	3	706	3e-59	223
rs:WP_003490066	DNA topoisomerase III [Xanthomonas citri].	26.93	698	454	18	1	658	1	682	3e-59	223
tr:D4K6W0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.77	559	354	12	138	671	1	551	3e-59	220
rs:WP_042554705	DNA topoisomerase III [Pseudomonas fulva].	26.44	609	404	13	1	578	1	596	3e-59	222
rs:WP_032881001	DNA topoisomerase III [Pseudomonas sp. BRG-100].	26.68	611	404	11	1	580	1	598	3e-59	222
rs:WP_005381063	MULTISPECIES: DNA topoisomerase [Veillonella].	27.96	633	396	16	1	581	1	625	3e-59	224
tr:A4JFS2_BURVG	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.08	624	402	14	2	581	3	617	3e-59	224
rs:WP_044995209	DNA topoisomerase III [Lachnospiraceae bacterium JC7].	27.99	661	381	19	3	580	4	652	3e-59	222
rs:WP_016440647	DNA topoisomerase III [Coprococcus sp. HPP0048].	29.04	637	382	21	5	579	7	635	3e-59	222
rs:WP_021624136	DNA topoisomerase [Aneurinibacillus aneurinilyticus].	27.09	705	422	21	3	668	4	655	4e-59	222
rs:WP_042350292	DNA topoisomerase III, partial [Escherichia coli].	33.03	445	270	12	161	581	1	441	4e-59	218
rs:WP_001235768	DNA topoisomerase III [Escherichia coli].	28.75	713	453	17	1	673	1	698	4e-59	223
rs:WP_042597590	DNA topoisomerase [Bacillus thuringiensis].	27.55	715	459	23	3	678	4	698	4e-59	223
rs:WP_026660106	DNA topoisomerase III [Butyrivibrio sp. AC2005].	28.13	679	396	22	3	601	5	671	4e-59	222
rs:WP_016231999	DNA topoisomerase III [Escherichia coli].	28.79	719	446	20	1	673	1	699	4e-59	223
rs:WP_035790822	DNA topoisomerase III [Butyrivibrio sp. FC2001].	28.74	696	388	23	3	608	5	682	4e-59	222
rs:WP_021966453	DNA topoisomerase III [Clostridium sp. CAG:149].	26.24	705	425	20	3	623	5	698	4e-59	223
rs:WP_031944022	TraE conjugative transfer protein, DNA topoisomerase [uncultured bacterium pAKD4].	27.15	652	421	15	1	614	1	636	4e-59	223
rs:WP_017643941	DNA topoisomerase [Streptococcus agalactiae].	34.21	494	286	12	98	580	23	488	4e-59	218
rs:WP_029364096	DNA topoisomerase III [Escherichia coli].	29.31	720	441	21	1	673	1	699	4e-59	223
tr:V5M5L7_BACTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.72	711	462	17	3	676	1	689	5e-59	223
rs:WP_010749200	DNA topoisomerase III, partial [Enterococcus casseliflavus].	30.53	547	355	11	3	528	4	546	5e-59	219
rs:WP_045721118	DNA topoisomerase III, partial [Salmonella enterica].	33.18	449	272	12	157	581	49	493	5e-59	219
rs:WP_032592777	DNA topoisomerase III, partial [Campylobacter jejuni].	30.49	610	378	17	1	574	1	600	5e-59	221
rs:WP_022351764	DNA topoisomerase [Firmicutes bacterium CAG:534].	27.71	646	392	18	3	580	5	643	5e-59	222
rs:WP_002686858	DNA topoisomerase III [Treponema denticola].	29.37	715	421	23	3	680	4	671	5e-59	222
rs:WP_025477548	DNA topoisomerase [Enterococcus faecium].	27.57	711	455	18	3	667	4	700	5e-59	223
rs:WP_043020510	DNA topoisomerase III, partial [Campylobacter jejuni].	30.49	610	378	17	1	574	1	600	5e-59	221
rs:WP_046617322	DNA topoisomerase III [Salmonella enterica].	28.67	715	452	19	1	673	1	699	5e-59	223
rs:WP_040121204	DNA topoisomerase III [Salmonella enterica].	28.57	714	454	18	1	673	1	699	5e-59	222
rs:WP_001722392	DNA topoisomerase III family protein [Escherichia coli].	28.99	714	451	18	1	673	1	699	5e-59	222
rs:WP_040949651	DNA topoisomerase III, partial [Paenibacillaceae bacterium G5].	31.14	578	328	19	3	530	4	561	5e-59	219
rs:WP_034394054	hypothetical protein, partial [Comamonas testosteroni].	26.19	691	445	15	1	640	1	677	5e-59	223
rs:WP_042971014	DNA topoisomerase I, partial [Bacteroides fragilis].	29.77	571	362	18	130	684	13	560	6e-59	219
tr:A0A015W1D8_BACFG	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EXY92028.1};	29.77	571	362	18	130	684	2	549	6e-59	219
rs:WP_042074080	DNA topoisomerase III, partial [Escherichia coli].	33.03	445	270	12	161	581	25	465	6e-59	218
rs:WP_004068688	DNA topoisomerase III [Clostridium sp. ASF502].	28.08	666	393	22	5	594	7	662	6e-59	221
rs:WP_008975260	DNA topoisomerase III [Lachnospiraceae bacterium 6_1_37FAA].	29.04	637	382	21	5	579	7	635	6e-59	222
rs:WP_029768989	hypothetical protein, partial [Ralstonia sp. JGI 0001001-A05].	27.82	611	375	18	1	573	1	583	6e-59	220
rs:WP_032596671	DNA topoisomerase I, partial [Bacteroides fragilis].	29.77	571	362	18	130	684	13	560	6e-59	219
rs:WP_001694638	DNA topoisomerase III family protein [Escherichia coli].	28.99	714	451	18	1	673	1	699	6e-59	222
rs:WP_001235763	DNA topoisomerase III [Escherichia coli].	28.99	714	451	18	1	673	1	699	6e-59	222
rs:WP_018708124	DNA topoisomerase [Bacillus fordii].	27.75	728	453	25	1	678	2	706	7e-59	222
rs:WP_019879542	hypothetical protein [Succinispira mobilis].	28.53	729	443	21	2	679	3	704	7e-59	222
rs:WP_042161815	DNA topoisomerase III [Paenibacillus sp. G1].	30.31	617	369	21	3	577	4	601	7e-59	223
rs:WP_022376747	DNA topoisomerase III [Clostridium sp. CAG:62].	29.10	653	380	22	2	581	4	646	7e-59	221
rs:WP_046977534	conjugal transfer protein TraE [Xanthomonas hyacinthi].	26.99	652	422	15	1	614	1	636	7e-59	222
rs:WP_009660877	DNA topoisomerase III [Veillonella sp. ACP1].	28.39	634	392	17	1	581	1	625	7e-59	223
rs:WP_019053936	conjugal transfer protein TraE [Sphingobium xenophagum].	26.47	646	421	15	3	614	6	631	8e-59	222
rs:WP_041617834	DNA topoisomerase III, partial [Paenibacillus mucilaginosus].	29.98	617	371	21	3	577	4	601	8e-59	221
rs:WP_024236815	DNA topoisomerase III [Escherichia coli].	28.57	714	454	18	1	673	1	699	8e-59	222
rs:WP_042095835	DNA topoisomerase III, partial [Escherichia coli].	33.03	445	270	12	161	581	27	467	8e-59	218
tr:A0A0E3BV48_COMTE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGH12677.1};	26.19	691	445	15	1	640	1	677	8e-59	222
rs:WP_034500952	hypothetical protein, partial [Butyrivibrio hungatei].	28.44	654	388	19	2	580	4	652	8e-59	221
rs:WP_043019033	DNA topoisomerase III, partial [Campylobacter jejuni].	30.49	610	378	17	1	574	1	600	8e-59	220
rs:WP_026490610	DNA topoisomerase III [Butyrivibrio sp. XPD2002].	28.02	696	393	22	3	608	5	682	8e-59	221
rs:WP_019241916	DNA topoisomerase [Bacillus massilioanorexius].	27.18	721	457	24	3	678	4	701	8e-59	222
rs:WP_040942445	DNA topoisomerase III [Xanthomonas campestris].	27.86	585	381	17	32	587	14	586	8e-59	222
rs:WP_031825907	DNA topoisomerase III, partial [Staphylococcus aureus].	30.17	600	383	14	3	580	4	589	9e-59	220
rs:WP_035792465	DNA topoisomerase [Butyrivibrio sp. AE3006].	25.60	754	477	22	2	679	4	749	9e-59	225
rs:WP_031836252	DNA topoisomerase III, partial [Staphylococcus aureus].	30.17	600	383	14	3	580	4	589	9e-59	219
rs:WP_036695438	DNA topoisomerase III [Paenibacillus sp. FSL R7-269].	28.59	612	382	20	3	577	4	597	9e-59	222
rs:WP_031789016	DNA topoisomerase III, partial [Staphylococcus aureus].	30.17	600	383	14	3	580	4	589	9e-59	219
rs:WP_029468581	DNA topoisomerase III [Clostridiales bacterium VE202-06].	28.53	638	390	18	3	579	5	637	1e-58	221
rs:WP_040058895	hypothetical protein [Bacillus sp. REN51N].	26.81	705	474	18	3	676	4	697	1e-58	223
rs:WP_021325878	DNA topoisomerase III [Photorhabdus temperata].	26.45	760	472	19	1	684	1	749	1e-58	222
rs:WP_009262078	DNA topoisomerase III [Coprococcus sp. HPP0074].	28.89	637	383	20	5	579	7	635	1e-58	221
rs:WP_018596389	DNA topoisomerase III [Blautia producta].	28.53	638	390	18	3	579	5	637	1e-58	221
tr:R9IKQ1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.51	544	337	12	148	673	13	533	1e-58	219
rs:WP_035796762	DNA topoisomerase [Butyrivibrio sp. MB2005].	25.46	754	478	21	2	679	4	749	1e-58	225
rs:WP_039630371	DNA topoisomerase [Clostridium argentinense].	27.67	741	447	23	3	679	4	719	1e-58	222
rs:WP_023662223	DNA topoisomerase [Pseudomonas taiwanensis].	27.29	711	445	22	3	663	5	693	1e-58	223
rs:WP_005962827	DNA topoisomerase III [Fusobacterium necrophorum].	36.12	371	217	9	1	365	1	357	1e-58	218
rs:WP_039996512	DNA topoisomerase III, partial [Flavonifractor plautii].	31.65	436	270	12	1	425	1	419	1e-58	216
tr:A0A068N6R0_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.29	581	359	13	70	623	1	562	1e-58	219
rs:WP_043924753	hypothetical protein [Bacillus thuringiensis].	27.22	687	439	16	23	676	22	680	1e-58	221
rs:WP_034462255	hypothetical protein, partial [Butyrivibrio sp. AE3003].	28.55	655	386	21	2	580	4	652	1e-58	221
rs:WP_038930464	DNA topoisomerase III, partial [Yersinia pestis].	32.58	445	272	12	161	581	29	469	1e-58	217
rs:WP_025478641	DNA topoisomerase [Enterococcus faecium].	27.57	711	455	18	3	667	4	700	1e-58	221
rs:WP_022433308	DNA topoisomerase [Eubacterium sp. CAG:38].	29.20	637	377	22	3	578	5	628	1e-58	220
rs:WP_037022461	MULTISPECIES: hypothetical protein, partial [Ralstonia].	27.51	607	380	17	1	575	1	579	1e-58	219
rs:WP_034468441	hypothetical protein, partial [Butyrivibrio sp. AE2005].	28.55	655	386	21	2	580	4	652	1e-58	221
rs:WP_033596185	DNA topoisomerase III, partial [Enterococcus faecalis].	32.24	425	263	10	2	413	5	417	1e-58	214
tr:D6DKA4_CLOSC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.24	705	425	20	3	623	5	698	1e-58	221
rs:WP_022091462	DNA topoisomerase III [Lachnospiraceae bacterium CAG:25].	28.41	637	387	18	3	580	4	630	2e-58	220
rs:WP_034217873	DNA topoisomerase III [Lachnospiraceae bacterium AB2028].	27.91	695	398	20	3	601	6	693	2e-58	221
rs:WP_045660704	DNA topoisomerase [Clostridiaceae bacterium BRH_c20a].	29.44	642	373	20	2	580	4	628	2e-58	219
tr:G9YLU1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.65	436	270	12	1	425	4	422	2e-58	216
rs:WP_029308519	DNA topoisomerase [Cupriavidus metallidurans].	26.69	723	424	24	1	629	1	711	2e-58	221
rs:WP_013617089	DNA topoisomerase III [Bacteroides salanitronis].	26.62	601	395	13	3	582	5	580	2e-58	219
rs:WP_042396023	DNA topoisomerase [Clostridium sp. JCC].	27.84	740	446	25	2	680	3	715	2e-58	221
rs:WP_016099670	DNA topoisomerase III [Bacillus cereus].	26.02	711	471	14	1	676	1	691	2e-58	221
rs:WP_024717739	MULTISPECIES: DNA topoisomerase [Pseudomonas].	27.29	711	445	22	3	663	5	693	2e-58	222
rs:WP_005823252	DNA topoisomerase I [Bacteroides fragilis].	27.00	637	421	17	68	680	6	622	2e-58	219
rs:WP_007545235	DNA topoisomerase III, partial [Listeria fleischmannii].	34.72	481	284	14	161	627	2	466	2e-58	218
tr:C3J9A0_9PORP	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEN83247.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EEN83247.1};	29.47	587	359	18	130	684	21	584	2e-58	219
rs:WP_015262647	DNA topoisomerase III [Desulfitobacterium dichloroeliminans].	26.39	773	456	25	3	676	5	763	2e-58	221
rs:WP_024639859	DNA topoisomerase III [Pseudomonas syringae].	26.80	735	465	22	1	684	1	713	2e-58	221
rs:WP_011171725	DNA topoisomerase III [Achromobacter denitrificans].	26.99	652	422	15	1	614	1	636	2e-58	221
rs:WP_010652035	DNA topoisomerase [Oceanobacillus massiliensis].	28.08	723	455	25	1	678	2	704	2e-58	221
rs:WP_005378468	DNA topoisomerase [Veillonella atypica].	28.23	634	393	17	1	581	1	625	2e-58	221
rs:WP_021983043	DNA topoisomerase III [Eubacterium sp. CAG:603].	28.73	651	381	19	5	580	7	649	2e-58	220
rs:WP_022097691	DNA topoisomerase [Eubacterium eligens CAG:72].	29.18	658	373	24	5	584	24	666	2e-58	220
rs:WP_023043465	hypothetical protein [Photorhabdus temperata].	26.45	760	472	19	1	684	1	749	3e-58	221
rs:WP_040015752	DNA topoisomerase III, partial [Dorea formicigenerans].	29.51	488	309	11	2	471	5	475	3e-58	215
rs:WP_038148583	DNA topoisomerase [Veillonella atypica].	27.76	634	396	16	1	581	1	625	3e-58	221
rs:WP_016171207	DNA topoisomerase III [Enterococcus faecium].	27.61	681	432	18	3	639	4	667	3e-58	219
tr:L1PX80_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.76	634	396	16	1	581	8	632	3e-58	221
rs:WP_012376245	DNA topoisomerase [Opitutus terrae].	28.44	675	405	25	3	610	5	668	3e-58	222
rs:WP_006954185	DNA topoisomerase III [Sphingobium japonicum].	26.47	646	421	15	3	614	6	631	3e-58	220
tr:W7WV89_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.10	423	257	10	166	563	10	431	3e-58	216
rs:WP_026696403	hypothetical protein [Bacillus chagannorensis].	27.15	733	458	27	1	681	1	709	3e-58	220
rs:WP_042744647	DNA topoisomerase III, partial [Staphylococcus aureus].	30.23	602	367	16	3	572	4	584	3e-58	218
rs:WP_022153122	DNA topoisomerase [Firmicutes bacterium CAG:65].	28.88	651	375	22	3	578	5	642	3e-58	219
rs:WP_000648780	DNA topoisomerase [Bacillus thuringiensis].	27.49	713	462	23	3	678	4	698	3e-58	220
rs:WP_042988804	hypothetical protein [Vibrio cholerae].	27.35	724	452	23	1	672	1	702	4e-58	220
rs:WP_046461889	DNA topoisomerase III [Comamonas testosteroni].	26.05	691	446	15	1	640	1	677	4e-58	220
rs:WP_033798183	DNA topoisomerase I [Bacillus mycoides].	28.65	705	452	24	3	675	5	690	4e-58	221
rs:WP_045048228	DNA topoisomerase III, partial [Rouxiella chamberiensis].	33.19	452	268	15	157	581	56	500	4e-58	216
rs:WP_008766575	DNA topoisomerase I [Bacteroides sp. 1_1_6].	26.92	639	419	17	68	680	6	622	4e-58	218
rs:WP_005348013	MULTISPECIES: DNA topoisomerase [Eubacterium].	27.55	726	456	22	2	680	3	705	4e-58	220
rs:WP_002370359	DNA topoisomerase III, partial [Enterococcus faecalis].	32.04	437	272	10	2	425	5	429	4e-58	215
rs:WP_022230861	DNA topoisomerase 3 (DNA topoisomerase III) [Firmicutes bacterium CAG:41].	27.73	732	445	20	1	671	1	709	4e-58	221
rs:WP_044983936	DNA topoisomerase III, partial [Lachnospiraceae bacterium 3_1_57FAA_CT1].	29.65	489	309	13	1	471	1	472	4e-58	215
rs:WP_034327551	MULTISPECIES: DNA topoisomerase III [Helicobacter].	29.71	653	391	21	1	612	1	626	4e-58	219
gp:CP006955_1251	DNA topoisomerase 3 [Bibersteinia trehalosi USDA-ARS-USMARC-189]	30.41	536	325	15	85	584	23	546	4e-58	217
rs:WP_014079867	DNA topoisomerase [Roseburia hominis].	25.70	755	456	22	3	662	5	749	4e-58	224
rs:WP_042722664	DNA topoisomerase I, partial [Flavobacterium sp. B17].	32.29	511	316	15	1	490	1	502	5e-58	215
rs:WP_031587950	DNA topoisomerase III [Lachnospiraceae bacterium P6A3].	29.42	656	370	21	3	578	5	647	5e-58	219
rs:WP_040580315	DNA topoisomerase I [Porphyromonas endodontalis].	29.47	587	359	18	130	684	59	622	5e-58	218
rs:WP_016110475	DNA topoisomerase III [Bacillus cereus].	28.63	702	452	24	3	673	5	688	5e-58	221
rs:WP_031833160	DNA topoisomerase III, partial [Staphylococcus aureus].	28.99	645	412	18	9	625	1	627	5e-58	219
rs:WP_033955320	DNA topoisomerase [Pseudomonas aeruginosa].	26.63	706	409	21	1	615	1	688	5e-58	219
rs:WP_015419613	MULTISPECIES: DNA topoisomerase III [Hydrogenobaculum].	29.84	697	364	23	2	615	3	657	5e-58	220
rs:WP_044923300	DNA topoisomerase III [Lachnospiraceae bacterium MA2020].	27.40	657	397	18	3	590	5	650	5e-58	219
rs:WP_039417357	DNA topoisomerase III [Xanthomonas euvesicatoria].	26.78	631	424	14	1	606	1	618	5e-58	220
tr:L3QI54_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.97	465	293	11	1	445	1	457	5e-58	214
rs:WP_041647890	hypothetical protein, partial [Aromatoleum aromaticum].	26.41	587	383	15	1	560	1	565	5e-58	217
tr:B0GA94_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.51	488	309	11	2	471	5	475	5e-58	215
rs:WP_023281073	hypothetical protein [Escherichia coli].	29.16	703	446	19	1	664	1	690	5e-58	220
rs:WP_032242288	DNA topoisomerase III, partial [Escherichia coli].	29.56	680	427	18	30	668	2	670	5e-58	219
rs:WP_015063531	TraE Conjugative transfer protein, DNA topoisomerase [Burkholderia cepacia].	26.84	652	423	15	1	614	1	636	5e-58	220
rs:WP_008701761	DNA topoisomerase [Fusobacterium nucleatum].	31.04	596	340	20	1	553	1	568	6e-58	218
rs:WP_022026173	DNA topoisomerase III [Clostridium sp. CAG:75].	29.92	655	368	25	2	578	4	645	6e-58	219
rs:WP_008391044	DNA topoisomerase III [Clostridium sp. SS2/1].	28.41	637	387	20	3	580	4	630	6e-58	218
rs:WP_021861155	DNA topoisomerase III [Dorea sp. CAG:105].	27.36	647	392	18	3	578	5	644	6e-58	219
rs:WP_044143441	hypothetical protein, partial [Succinimonas amylolytica].	28.99	621	366	20	2	560	4	611	6e-58	219
rs:WP_032349584	DNA topoisomerase III [Escherichia coli].	28.85	714	452	18	1	673	1	699	6e-58	219
rs:WP_034491856	DNA topoisomerase III, partial [Butyrivibrio fibrisolvens].	28.77	664	382	19	3	580	5	663	6e-58	218
rs:WP_026504229	DNA topoisomerase III [Butyrivibrio sp. NC3005].	29.16	679	385	24	3	594	5	674	6e-58	219
rs:WP_019741001	DNA topoisomerase III [Pseudomonas savastanoi].	26.98	734	465	22	1	684	1	713	6e-58	219
rs:WP_005805288	MULTISPECIES: DNA topoisomerase I [Bacteroides].	27.00	637	421	17	68	680	6	622	7e-58	218
rs:WP_016290736	DNA topoisomerase III [Lachnospiraceae bacterium 28-4].	28.26	644	390	18	3	580	5	642	7e-58	218
rs:WP_039848609	DNA topoisomerase I [Parabacteroides sp. D13].	27.10	642	414	18	68	680	6	622	7e-58	218
rs:WP_038268239	DNA topoisomerase [[Clostridium] litorale].	28.51	726	449	28	2	680	3	705	7e-58	219
tr:F7KHC2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.65	489	309	13	1	471	1	472	7e-58	214
tr:J9C8M6_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.30	538	327	12	1	507	1	521	7e-58	215
tr:K1U494_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC73180.1}; Flags: Fragment;	33.42	368	221	8	1	360	14	365	7e-58	211
rs:WP_016475404	DNA topoisomerase III [Veillonella sp. HPA0037].	27.80	633	397	17	1	581	1	625	7e-58	220
rs:WP_017694259	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	29.16	703	446	19	1	664	1	690	8e-58	219
rs:WP_029232734	DNA topoisomerase [Butyrivibrio sp. VCB2006].	25.20	762	477	23	2	679	4	756	8e-58	223
rs:WP_018783115	DNA topoisomerase I [Bacillus sp. 95MFCvi2.1].	28.47	706	452	22	3	675	5	690	8e-58	221
rs:WP_022389358	DNA topoisomerase III [Ruminococcus obeum CAG:39].	28.22	684	408	23	3	613	5	678	8e-58	218
rs:WP_004192797	DNA topoisomerase III [Klebsiella pneumoniae].	29.02	703	447	19	1	664	1	690	9e-58	219
rs:WP_031878368	DNA topoisomerase III, partial [Staphylococcus aureus].	32.38	491	301	14	3	480	4	476	9e-58	214
rs:WP_025480889	DNA topoisomerase III [Enterococcus faecium].	27.90	681	430	18	3	639	4	667	9e-58	218
rs:WP_016362617	DNA topoisomerase III [Paenibacillus mucilaginosus].	29.61	618	372	21	3	577	4	601	1e-57	220
tr:N1ZTU5_9FIRM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EMZ19346.1};	28.80	566	357	15	145	683	10	556	1e-57	216
rs:WP_044962176	DNA topoisomerase III, partial [Blautia sp. KLE 1732].	34.58	373	220	10	1	365	1	357	1e-57	211
rs:WP_035528896	hypothetical protein, partial [Haliea salexigens].	27.00	626	401	19	1	581	1	615	1e-57	217
rs:WP_022268381	DNA topoisomerase [Firmicutes bacterium CAG:424].	29.26	646	375	21	3	579	5	637	1e-57	218
tr:C9ANH7_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.93	643	410	17	68	673	1	633	1e-57	218
rs:WP_034484200	DNA topoisomerase III, partial [Butyrivibrio fibrisolvens].	28.81	663	383	19	3	580	5	663	1e-57	218
rs:WP_022173204	DNA topoisomerase [Blautia sp. CAG:52].	27.66	676	397	19	3	594	5	672	1e-57	218
rs:WP_034022901	DNA topoisomerase [Pseudomonas aeruginosa].	26.45	707	410	21	1	615	1	689	1e-57	219
rs:WP_033143458	DNA topoisomerase III [Blautia producta].	28.12	640	390	19	3	579	5	637	1e-57	218
rs:WP_044931349	DNA topoisomerase III [Clostridium sp. M62/1].	26.10	705	426	20	3	623	5	698	1e-57	219
rs:WP_025154735	hypothetical protein [Morganella morganii].	27.81	730	468	17	1	687	1	714	1e-57	218
rs:WP_033965820	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	29.32	556	355	13	84	611	5	550	1e-57	216
rs:WP_032575310	DNA topoisomerase I [Bacteroides fragilis].	27.00	637	421	17	68	680	6	622	1e-57	217
rs:WP_043004228	DNA topoisomerase III, partial [Vibrio anguillarum].	31.24	509	307	10	108	581	6	506	1e-57	215
rs:WP_043935294	MULTISPECIES: hypothetical protein [Bacillus].	27.01	685	443	15	23	676	22	680	1e-57	218
rs:WP_027424895	DNA topoisomerase III [Lachnospiraceae bacterium NC2004].	28.35	649	386	20	5	582	7	647	1e-57	218
tr:D4CEE7_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.10	705	426	20	3	623	20	713	1e-57	219
rs:WP_042346581	DNA topoisomerase [Bacillus sp. G2(2012b)].	27.89	717	455	24	3	678	5	700	1e-57	218
rs:WP_034490071	DNA topoisomerase III [Butyrivibrio fibrisolvens].	28.66	663	384	19	3	580	5	663	1e-57	218
rs:WP_031786070	DNA topoisomerase III, partial [Staphylococcus aureus].	29.11	608	396	16	40	625	3	597	1e-57	216
rs:WP_026891460	DNA topoisomerase III [[Clostridium] aerotolerans].	27.42	660	385	19	3	578	5	654	2e-57	218
rs:WP_021849768	DNA topoisomerase III [Firmicutes bacterium CAG:791].	27.86	646	389	20	2	578	4	641	2e-57	218
rs:WP_031909704	DNA topoisomerase III, partial [Staphylococcus aureus].	32.18	491	302	14	3	480	4	476	2e-57	214
rs:WP_026497541	DNA topoisomerase III [Butyrivibrio sp. WCD2001].	27.50	669	402	22	3	596	5	665	2e-57	218
rs:WP_004010072	DNA topoisomerase, partial [Escherichia coli].	28.57	686	438	17	26	670	6	680	2e-57	218
rs:WP_006566846	DNA topoisomerase III [Anaerostipes caccae].	28.18	653	392	21	3	594	10	646	2e-57	218
rs:WP_027641614	DNA topoisomerase III [[Clostridium] clostridioforme].	28.03	660	382	18	3	578	5	655	2e-57	218
rs:WP_032640105	DNA topoisomerase III [Enterobacter sp. EGD-HP1].	29.46	706	440	21	1	664	1	690	2e-57	218
sp:TOP1_BACPE	RecName: Full=DNA topoisomerase 1; EC=5.99.1.2; AltName: Full=DNA topoisomerase I; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	28.25	715	427	23	1	661	1	683	2e-57	218
rs:WP_040982951	DNA topoisomerase [Oceanobacillus sp. S5].	28.93	726	449	24	1	679	1	706	2e-57	218
rs:WP_022752908	DNA topoisomerase III [Butyrivibrio fibrisolvens].	28.81	663	383	19	3	580	5	663	2e-57	218
tr:C9BBV7_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.93	643	410	17	68	673	1	633	2e-57	217
rs:WP_001241818	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	29.02	703	447	19	1	664	1	690	2e-57	218
rs:WP_001776115	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	29.16	703	446	19	1	664	1	690	2e-57	218
rs:WP_029657514	DNA topoisomerase III, partial [Staphylococcus aureus].	29.11	608	396	16	40	625	13	607	2e-57	217
rs:WP_034367860	hypothetical protein, partial [Comamonas testosteroni].	26.22	694	441	17	1	640	1	677	2e-57	218
rs:WP_002205096	DNA topoisomerase I [Bacillus cereus].	28.29	707	448	24	3	673	5	688	2e-57	219
rs:WP_031762110	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	28.74	581	369	16	84	629	7	577	2e-57	216
rs:WP_030061483	MULTISPECIES: DNA topoisomerase III [Staphylococcus].	29.15	645	412	17	3	620	4	630	2e-57	218
rs:WP_033168144	DNA topoisomerase III [Clostridium sp. KNHs205].	27.51	687	394	22	3	593	5	683	2e-57	218
rs:WP_024835747	DNA topoisomerase III [Clostridium sp. 12(A)].	27.27	660	386	18	3	578	5	654	2e-57	217
rs:WP_045369874	DNA topoisomerase III [Enterobacter asburiae].	29.16	703	446	19	1	664	1	690	2e-57	218
rs:WP_034486619	DNA topoisomerase III [Butyrivibrio fibrisolvens].	28.77	664	382	19	3	580	5	663	2e-57	218
rs:WP_022757070	DNA topoisomerase III [Butyrivibrio fibrisolvens].	28.66	663	384	19	3	580	5	663	2e-57	218
rs:WP_040466192	DNA topoisomerase III, partial [Holdemanella biformis].	32.35	439	275	9	1	430	1	426	2e-57	213
rs:WP_043313879	DNA topoisomerase III, partial [Bacillus cereus].	30.17	537	327	12	1	506	1	520	2e-57	214
tr:B7C9A6_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.43	441	272	10	1	430	1	426	3e-57	213
tr:A0A096FM68_COMTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.22	694	441	17	1	640	1	677	3e-57	218
tr:C9AEQ4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.93	643	410	17	68	673	1	633	3e-57	217
rs:WP_032666425	DNA topoisomerase III [Enterobacter cloacae].	29.16	703	446	19	1	664	1	690	3e-57	218
rs:WP_038565766	DNA topoisomerase [Terribacillus aidingensis].	28.75	720	451	27	1	678	1	700	3e-57	217
tr:A0A0D5V227_9BURK	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:AJZ56126.1};	27.87	653	394	21	3	615	4	619	3e-57	219
tr:I3V5K3_PSEPU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.49	706	410	21	1	615	1	688	3e-57	217
rs:WP_033869006	DNA topoisomerase III, partial [Staphylococcus aureus].	31.83	509	306	13	125	615	2	487	3e-57	215
rs:WP_011988545	DNA topoisomerase III [Yersinia pseudotuberculosis].	27.47	728	445	23	3	673	6	707	3e-57	218
rs:WP_031835761	DNA topoisomerase III, partial [Staphylococcus aureus].	29.11	608	396	16	40	625	7	601	3e-57	216
rs:WP_005549947	DNA topoisomerase III [Paenibacillus alvei].	28.41	630	373	19	3	577	4	610	3e-57	218
rs:WP_028529857	DNA topoisomerase III [Ruminococcus gauvreauii].	27.04	636	398	17	3	578	5	634	3e-57	216
rs:WP_042978736	DNA topoisomerase I [Bacillus mycoides].	29.07	712	440	26	3	675	5	690	4e-57	219
rs:WP_033421242	DNA topoisomerase, partial [Lachnobacterium bovis].	26.25	659	409	17	3	595	5	652	4e-57	216
rs:WP_023100649	hypothetical protein [Pseudomonas aeruginosa].	27.21	713	397	24	1	615	1	689	4e-57	217
tr:V1WH61_SALMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.11	456	273	11	157	581	1	455	4e-57	213
rs:WP_035651436	hypothetical protein, partial [Lachnospiraceae bacterium AD3010].	27.37	665	379	18	3	580	5	652	4e-57	216
rs:WP_034225946	DNA topoisomerase, partial [Lachnobacterium bovis].	26.45	654	414	16	3	595	5	652	4e-57	216
rs:WP_045391803	hypothetical protein [Vibrio rotiferianus].	27.39	639	408	16	1	600	1	622	4e-57	215
rs:WP_042882881	hypothetical protein [Cupriavidus necator].	27.73	631	397	16	2	581	5	627	4e-57	216
rs:WP_022207365	DNA topoisomerase [Eubacterium sp. CAG:252].	28.05	663	377	22	5	587	7	649	4e-57	216
rs:WP_023118088	hypothetical protein [Pseudomonas aeruginosa].	26.59	707	408	22	1	615	1	688	4e-57	217
rs:WP_022375749	DNA topoisomerase III [Firmicutes bacterium CAG:270].	27.93	641	385	19	3	580	4	630	4e-57	216
rs:WP_001094110	DNA topoisomerase III [Staphylococcus aureus].	28.99	645	413	17	3	620	4	630	5e-57	216
rs:WP_040118784	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	28.01	714	455	25	3	679	5	696	5e-57	218
tr:A0A0D4ZYL4_STAEP	SubName: Full=Putative relaxase TraI {ECO:0000313|EMBL:AJW29115.1};	28.99	645	413	17	3	620	4	630	5e-57	216
rs:WP_009289563	MULTISPECIES: DNA topoisomerase III [Anaerostipes].	28.33	639	384	20	3	580	4	629	5e-57	216
rs:WP_039652910	hypothetical protein [Clostridium tyrobutyricum].	28.33	706	452	23	1	673	1	685	6e-57	217
rs:WP_021974742	DNA topoisomerase [Firmicutes bacterium CAG:884].	29.34	709	441	26	1	680	1	678	6e-57	216
rs:WP_022398796	DNA topoisomerase [Roseburia sp. CAG:471].	27.92	677	394	20	3	594	5	672	6e-57	216
tr:N9YPK9_9FIRM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ENZ09687.1};	29.06	585	364	16	122	683	10	566	6e-57	214
rs:WP_010890147	hypothetical protein [Enterobacter aerogenes].	27.73	660	414	17	1	614	1	643	6e-57	216
rs:WP_004666997	DNA topoisomerase III [Pseudomonas savastanoi].	26.74	733	468	23	1	684	1	713	6e-57	216
rs:WP_032679819	DNA topoisomerase III [Enterobacter sp. BIDMC 26].	26.42	757	454	21	2	675	3	739	7e-57	217
rs:WP_017879692	hypothetical protein [Janthinobacterium sp. CG3].	27.18	618	400	12	1	578	1	608	7e-57	216
rs:WP_019638659	DNA topoisomerase III [Paenibacillus fonticola].	28.43	605	380	19	3	571	4	591	7e-57	217
rs:WP_022759902	DNA topoisomerase III [Butyrivibrio sp. AD3002].	28.32	678	384	25	3	596	5	664	7e-57	216
rs:WP_041688620	DNA topoisomerase III [[Eubacterium] eligens].	28.88	658	375	24	5	584	7	649	7e-57	216
rs:WP_044976667	hypothetical protein [Ruminococcus sp. HUN007].	27.56	733	449	23	1	679	1	705	8e-57	216
rs:WP_022010842	DNA topoisomerase III [Firmicutes bacterium CAG:646].	28.55	655	376	21	3	579	5	645	8e-57	216
rs:WP_005746149	DNA topoisomerase III [Pseudomonas amygdali].	26.90	736	463	23	1	684	1	713	8e-57	216
rs:WP_021253879	DNA topoisomerase III [Paenibacillus alvei].	26.78	646	415	16	3	605	4	634	8e-57	217
rs:WP_002667236	DNA topoisomerase III [Capnocytophaga gingivalis].	26.82	727	466	18	1	673	1	715	8e-57	216
tr:A0A095FRA6_BURML	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.21	670	404	25	3	631	4	637	8e-57	217
rs:WP_042223993	DNA topoisomerase [Oceanobacillus manasiensis].	28.41	725	456	25	1	681	1	706	9e-57	216
rs:WP_028533041	DNA topoisomerase III [Paenibacillus sp. UNC217MF].	27.30	652	404	18	3	605	4	634	9e-57	216
tr:C4Z0Y0_EUBE2	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.88	658	375	24	5	584	24	666	9e-57	216
rs:WP_046932826	DNA topoisomerase III [Xanthomonas perforans].	27.29	612	407	14	1	587	1	599	9e-57	216
rs:WP_021941314	DNA topoisomerase [Clostridium sp. CAG:632].	29.06	647	374	22	3	578	4	636	9e-57	215
rs:WP_008451377	DNA topoisomerase, partial [Prevotella amnii].	29.64	668	385	25	66	673	7	649	9e-57	215
rs:WP_027439694	DNA topoisomerase III [Lachnospiraceae bacterium AC2031].	29.17	665	369	23	2	578	3	653	1e-56	215
tr:U2DIJ0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.32	373	221	10	1	365	8	364	1e-56	209
tr:D4LSE8_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.46	643	388	21	3	579	5	641	1e-56	215
rs:WP_043032798	hypothetical protein [Clostridium botulinum].	28.94	705	446	22	2	677	3	681	1e-56	216
rs:WP_001235766	DNA topoisomerase III [Escherichia albertii].	28.95	708	448	18	1	668	1	693	1e-56	216
rs:WP_021261414	DNA topoisomerase III [Paenibacillus alvei].	27.30	652	404	18	3	605	4	634	1e-56	216
rs:WP_029437123	DNA topoisomerase I [Bacillus thuringiensis].	28.15	707	449	24	3	673	5	688	1e-56	217
rs:WP_038309401	DNA topoisomerase III [Kingella kingae].	27.76	735	439	25	3	682	5	702	1e-56	216
rs:WP_035393821	DNA topoisomerase III, partial [Faecalibacterium prausnitzii].	32.35	408	254	10	2	399	8	403	1e-56	211
rs:WP_006427278	DNA topoisomerase III [Dorea longicatena].	27.44	667	396	21	3	594	5	658	1e-56	215
rs:WP_031358079	DNA topoisomerase III, partial [Burkholderia sordidicola].	29.13	611	368	20	3	574	4	588	1e-56	213
rs:WP_005609809	DNA topoisomerase III [Ruminococcus lactaris].	27.81	676	396	20	3	594	5	672	1e-56	215
tr:C9B5N6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.77	643	411	17	68	673	1	633	1e-56	215
tr:Q3II03_PSEHT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.44	447	271	9	161	580	14	456	1e-56	211
rs:WP_040191961	DNA topoisomerase [Clostridium sp. CL-6].	26.70	749	458	26	2	679	3	731	1e-56	216
rs:WP_021635830	DNA topoisomerase III [Clostridium sp. KLE 1755].	28.39	715	393	28	3	613	5	704	2e-56	215
tr:R5HV76_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.01	648	400	17	3	583	5	646	2e-56	215
rs:WP_034549249	DNA topoisomerase III [Clostridiales bacterium VE202-09].	27.91	652	395	21	3	594	10	646	2e-56	214
rs:WP_025489788	DNA topoisomerase III [Clostridiales bacterium VE202-27].	28.15	714	396	27	3	613	5	704	2e-56	215
rs:WP_031580844	DNA topoisomerase III [Lachnospiraceae bacterium AC2028].	28.55	669	373	21	3	579	5	660	2e-56	214
rs:WP_003436835	MULTISPECIES: DNA topoisomerase III [Pseudomonas syringae group].	26.60	733	469	21	1	684	1	713	2e-56	215
rs:WP_038303891	DNA topoisomerase III [Kingella kingae].	27.76	735	439	25	3	682	5	702	2e-56	215
rs:WP_035344579	DNA topoisomerase [Bacillus hemicellulosilyticus].	28.39	715	456	22	1	676	1	698	2e-56	215
rs:WP_034446774	DNA topoisomerase [Butyrivibrio sp. AE2032].	25.20	758	476	21	3	677	5	754	2e-56	218
rs:WP_038136279	DNA topoisomerase III [Verrucomicrobia bacterium SCGC AAA168-F10].	26.75	729	458	24	3	678	5	710	2e-56	216
rs:WP_017473361	hypothetical protein [Amphibacillus jilinensis].	27.71	729	453	23	1	677	1	707	2e-56	215
rs:WP_017752917	hypothetical protein [Clostridium tyrobutyricum].	28.33	706	452	23	1	673	1	685	3e-56	215
rs:WP_022263573	DNA topoisomerase III [Butyrivibrio sp. CAG:318].	27.83	654	386	20	3	578	5	650	3e-56	214
tr:V1XDB5_SALMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.68	456	275	12	157	581	1	455	3e-56	211
rs:WP_032221747	DNA topoisomerase III, partial [Escherichia coli].	28.61	685	437	17	30	673	2	675	3e-56	214
rs:WP_016186698	DNA topoisomerase III, partial [Staphylococcus aureus].	33.72	436	263	13	3	425	4	426	3e-56	208
tr:E3PWY5_CLOSD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.49	641	376	20	65	636	16	649	3e-56	214
rs:WP_002643085	DNA topoisomerase III [Simonsiella muelleri].	28.12	736	432	25	3	682	5	699	3e-56	214
rs:WP_001094108	hypothetical protein [Bacillus cereus].	27.85	657	418	18	3	614	4	649	3e-56	215
rs:WP_032133432	DNA topoisomerase III [Kingella kingae].	27.97	733	437	27	3	682	5	699	3e-56	214
rs:WP_005364064	DNA topoisomerase III [Eubacterium ventriosum].	28.70	683	364	24	3	579	4	669	3e-56	214
rs:WP_005997465	DNA topoisomerase III [Xanthomonas vesicatoria].	26.96	612	409	14	1	587	1	599	3e-56	214
rs:WP_044593794	DNA topoisomerase III, partial [Cronobacter sakazakii].	32.59	448	249	19	1	410	1	433	3e-56	209
rs:WP_039657745	hypothetical protein [Clostridium tyrobutyricum].	28.33	706	452	23	1	673	1	685	3e-56	215
rs:WP_026287158	hypothetical protein [Gilvimarinus chinensis].	26.69	682	439	17	3	640	6	670	3e-56	214
rs:WP_006717210	DNA topoisomerase III [Desulfitobacterium metallireducens].	25.44	794	458	23	3	673	5	787	4e-56	215
rs:WP_032121812	DNA topoisomerase [Clostridium sp. LF2].	30.05	609	370	18	2	574	3	591	4e-56	213
rs:WP_005782553	MULTISPECIES: DNA topoisomerase III [Pseudomonas syringae group].	27.38	734	462	26	1	684	1	713	4e-56	214
rs:WP_007857917	DNA topoisomerase III [[Clostridium] citroniae].	26.54	667	394	16	3	578	5	666	4e-56	214
rs:WP_013978336	DNA topoisomerase III [Clostridium sp. SY8519].	27.34	684	412	23	3	613	5	676	4e-56	214
tr:E3GMG1_EUBLK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.03	717	450	26	3	676	4	697	4e-56	215
rs:WP_003526249	hypothetical protein, partial [[Clostridium] clostridioforme].	33.07	375	225	9	1	366	1	358	4e-56	206
tr:M5JHB5_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.17	404	240	11	4	391	5	394	4e-56	207
rs:WP_029453315	DNA topoisomerase III [Clostridium algidicarnis].	30.61	611	364	21	2	574	3	591	4e-56	213
rs:WP_042276999	hypothetical protein, partial [Burkholderia fungorum].	28.10	612	376	19	3	574	4	591	4e-56	212
rs:WP_016296807	hypothetical protein [Lachnospiraceae bacterium M18-1].	27.90	699	394	23	5	606	7	692	4e-56	214
rs:WP_004367385	DNA topoisomerase TopB, partial [Prevotella nigrescens].	30.62	578	363	16	111	673	1	555	5e-56	211
rs:WP_035639814	hypothetical protein, partial [Lachnospiraceae bacterium ND2006].	29.53	640	382	22	3	585	5	632	5e-56	213
rs:WP_003207662	DNA topoisomerase I [Bacillus mycoides].	28.21	716	441	25	3	675	5	690	5e-56	215
rs:WP_021774656	DNA topoisomerase III [Oribacterium sp. oral taxon 078].	26.80	638	400	18	2	579	3	633	5e-56	213
tr:A0A075G5E7_9EURY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.72	725	442	21	2	677	3	694	5e-56	215
rs:WP_016622814	DNA topoisomerase, partial [Enterococcus faecalis].	27.95	533	358	9	3	513	4	532	5e-56	210
rs:WP_009767084	DNA topoisomerase [Moraxella macacae].	27.41	664	415	20	1	615	1	646	5e-56	214
tr:Q2BXW9_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.73	440	266	8	161	574	66	501	5e-56	211
rs:WP_031537411	DNA topoisomerase III, partial [Bacillus sp. MB2021].	34.84	376	213	11	3	361	4	364	5e-56	206
rs:WP_006441522	DNA topoisomerase III [[Clostridium] hylemonae].	27.92	659	401	22	3	594	5	656	5e-56	213
rs:WP_031804216	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	28.65	576	366	16	89	629	1	566	6e-56	211
tr:R9HPA4_BACUN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOS05606.1};	28.49	558	376	13	130	677	2	546	6e-56	211
rs:WP_016569421	DNA topoisomerase III [Pseudomonas syringae].	26.53	735	467	22	1	684	1	713	6e-56	214
rs:WP_044707261	DNA topoisomerase III [Escherichia coli].	28.67	708	450	18	1	668	1	693	6e-56	213
rs:WP_024690810	DNA topoisomerase III [Pseudomonas syringae].	27.01	733	466	24	1	684	1	713	7e-56	213
rs:WP_009215951	DNA topoisomerase III [Oribacterium sp. oral taxon 078].	26.42	636	405	16	2	579	3	633	7e-56	212
rs:WP_008751237	DNA topoisomerase III [Lachnoanaerobaculum saburreum].	27.87	635	392	14	2	578	3	629	7e-56	213
rs:WP_013657846	DNA topoisomerase [Cellulosilyticum lentocellum].	27.24	749	454	24	2	678	3	732	7e-56	214
rs:WP_034587670	DNA topoisomerase III [Helicobacter magdeburgensis].	28.72	658	414	20	1	620	1	641	7e-56	214
rs:WP_042226552	DNA topoisomerase III [Kingella kingae].	27.62	735	440	25	3	682	5	702	8e-56	213
rs:WP_041487960	DNA topoisomerase III, partial [Bacillus thuringiensis].	29.68	529	332	11	1	502	1	516	8e-56	209
rs:WP_022089074	DNA topoisomerase [Eubacterium sp. CAG:156].	28.87	665	376	23	3	579	5	660	8e-56	213
tr:D2U0X3_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.69	697	437	16	25	673	11	688	8e-56	213
tr:C3DIJ7_BACTS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.68	529	332	11	1	502	1	516	8e-56	209
rs:WP_035417998	hypothetical protein, partial [Ferrovum myxofaciens].	28.08	584	372	15	3	560	6	567	8e-56	211
rs:WP_022150917	DNA topoisomerase III [Lachnospiraceae bacterium CAG:215].	28.45	682	381	25	5	594	7	673	9e-56	213
rs:WP_042923338	DNA topoisomerase [Pseudomonas chloritidismutans].	27.30	641	371	19	1	564	1	623	9e-56	213
rs:WP_020151346	hypothetical protein [Verrucomicrobia bacterium SCGC AAA164-M04].	28.03	660	400	23	3	610	5	641	9e-56	214
rs:WP_033962387	DNA topoisomerase [Pseudomonas aeruginosa].	27.30	641	371	19	1	564	1	623	9e-56	213
rs:WP_035458144	hypothetical protein, partial [Bacteroides uniformis].	28.49	558	376	13	130	677	3	547	9e-56	210
rs:WP_022140739	DNA topoisomerase III [Clostridium sp. CAG:230].	28.40	676	373	22	3	578	5	669	9e-56	213
rs:WP_021640983	DNA topoisomerase III [[Clostridium] symbiosum].	27.92	659	384	20	3	578	5	655	9e-56	213
rs:WP_022278616	MULTISPECIES: DNA topoisomerase III [Dorea].	26.97	686	399	19	3	594	5	682	9e-56	213
rs:WP_005336206	DNA topoisomerase III [Dorea formicigenerans].	26.97	686	399	19	3	594	5	682	1e-55	213
tr:R9N328_9FIRM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOS77715.1};	29.59	588	354	18	138	682	1	571	1e-55	211
rs:WP_013385940	DNA topoisomerase III [Paenibacillus polymyxa].	26.90	699	448	20	3	667	4	673	1e-55	214
rs:WP_044320067	DNA topoisomerase III [Pseudomonas amygdali].	26.60	733	469	21	1	684	1	713	1e-55	213
rs:WP_012720245	hypothetical protein [Clostridium botulinum].	29.08	705	445	22	2	677	3	681	1e-55	213
rs:WP_017895115	hypothetical protein [Clostridium tyrobutyricum].	28.19	706	453	23	1	673	1	685	1e-55	213
rs:WP_014029288	DNA topoisomerase III [Acidithiobacillus ferrivorans].	29.93	548	322	15	1	514	1	520	1e-55	211
rs:WP_044423982	DNA topoisomerase III [Pseudomonas savastanoi].	27.21	735	462	24	1	684	1	713	1e-55	213
rs:WP_041114280	DNA topoisomerase [Bacillus badius].	28.12	722	453	22	1	675	1	703	1e-55	213
rs:WP_022319653	DNA topoisomerase [Dorea sp. CAG:317].	27.46	630	396	18	3	578	5	627	1e-55	212
rs:WP_003510596	MULTISPECIES: DNA topoisomerase III [Clostridiales].	27.92	659	384	20	3	578	5	655	1e-55	213
rs:WP_019331405	DNA topoisomerase III [Pseudomonas syringae].	26.88	733	467	23	1	684	1	713	1e-55	213
rs:WP_024732370	DNA topoisomerase III [Clostridiales bacterium VE202-14].	27.72	635	394	18	3	578	5	633	1e-55	212
rs:WP_028087700	DNA topoisomerase III [Dorea longicatena].	27.67	665	399	20	3	594	5	660	1e-55	212
rs:WP_032494930	DNA topoisomerase [Enterococcus faecium].	28.86	551	344	12	3	520	34	569	1e-55	210
rs:WP_032708797	DNA topoisomerase, partial [Pseudomonas syringae].	27.97	733	440	24	3	673	5	711	2e-55	213
rs:WP_042598621	DNA topoisomerase III, partial [Bacillus thuringiensis].	29.68	529	332	11	1	502	1	516	2e-55	209
rs:WP_041100934	DNA topoisomerase [Bacillus badius].	28.12	722	453	23	1	675	1	703	2e-55	213
rs:WP_022201940	DNA topoisomerase III [Clostridium clostridioforme CAG:132].	27.62	677	380	18	3	578	5	672	2e-55	212
rs:WP_021953303	DNA topoisomerase [Eubacterium sp. CAG:161].	28.78	681	361	26	3	579	5	665	2e-55	212
rs:WP_022066938	DNA topoisomerase III [Blautia sp. CAG:257].	27.05	647	392	20	3	579	5	641	2e-55	212
rs:WP_045092577	DNA topoisomerase III [Clostridium sp. FS41].	26.39	667	395	16	3	578	5	666	2e-55	212
rs:WP_035114448	DNA topoisomerase [Clostridium sp. NCR].	27.16	740	436	27	1	677	1	700	2e-55	212
rs:WP_040800395	DNA topoisomerase III [Stomatobaculum longum].	26.76	695	420	21	2	622	3	682	2e-55	212
rs:WP_017513937	hypothetical protein, partial [beta proteobacterium FWI2].	28.12	537	352	13	1	511	1	529	2e-55	209
rs:WP_045666083	DNA topoisomerase [Pseudomonas sp. BRH_c35].	27.30	641	371	19	1	564	1	623	2e-55	212
tr:A0A0D0I5N4_BACTM	SubName: Full=TopB protein {ECO:0000313|EMBL:KIP26822.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIP26822.1};	29.68	529	332	11	1	502	1	516	2e-55	209
rs:WP_009428925	DNA topoisomerase III [Oribacterium sp. oral taxon 108].	26.51	645	399	18	2	580	3	638	2e-55	211
rs:WP_005614699	DNA topoisomerase III [Pseudomonas avellanae].	26.60	733	469	23	1	684	1	713	2e-55	212
rs:WP_009268350	DNA topoisomerase III [Lachnospiraceae bacterium 1_4_56FAA].	28.53	680	383	25	5	594	7	673	2e-55	212
rs:WP_044947806	DNA topoisomerase III [Blautia schinkii].	28.11	651	383	20	3	579	5	644	2e-55	211
rs:WP_004461886	DNA topoisomerase III [[Clostridium] symbiosum].	27.92	659	384	20	3	578	5	655	2e-55	212
tr:C2BCN7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.95	432	251	10	155	579	20	428	2e-55	206
rs:WP_022423482	DNA topoisomerase [Clostridium sp. CAG:440].	33.41	449	246	13	2	404	4	445	2e-55	207
rs:WP_040259218	DNA topoisomerase III [Pseudomonas sp. CB1].	26.59	737	466	23	1	684	1	715	2e-55	212
rs:WP_021432150	DNA topoisomerase [[Clostridium] bifermentans].	27.42	744	429	28	1	677	1	700	2e-55	212
rs:WP_044377079	DNA topoisomerase III, partial [Escherichia coli].	30.98	481	292	18	1	452	1	470	2e-55	207
rs:WP_033608220	topoisomerase I, partial [Lactobacillus plantarum].	29.27	615	401	14	3	592	4	609	2e-55	211
rs:WP_003524692	hypothetical protein, partial [[Clostridium] clostridioforme].	33.16	374	224	9	2	366	5	361	2e-55	204
rs:WP_008372305	MULTISPECIES: DNA topoisomerase III [Coprococcus].	28.08	641	389	19	5	578	7	642	2e-55	211
rs:WP_046400357	DNA topoisomerase III, partial [Staphylococcus aureus].	33.49	436	264	13	3	425	4	426	3e-55	206
rs:WP_021866241	DNA topoisomerase [Eubacterium sp. CAG:86].	27.73	649	386	21	3	580	5	641	3e-55	211
rs:WP_003021050	DNA topoisomerase III [Blautia hansenii].	27.84	643	388	16	3	579	5	637	3e-55	211
rs:WP_041703756	DNA topoisomerase III [Lachnoclostridium phytofermentans].	28.41	697	373	23	3	583	5	691	3e-55	212
rs:WP_015851562	DNA topoisomerase type IA central domain-containing protein [Desulfovibrio salexigens].	26.35	683	435	18	1	640	1	658	3e-55	212
rs:WP_019740450	DNA topoisomerase III, partial [Pseudomonas savastanoi].	28.44	559	362	13	100	629	4	553	3e-55	209
rs:WP_044013492	hypothetical protein [Treponema sp. OMZ 838].	29.73	740	413	28	1	683	1	690	3e-55	211
rs:WP_016292371	DNA topoisomerase III [Lachnospiraceae bacterium 28-4].	28.92	581	375	15	112	671	1	564	3e-55	209
rs:WP_031834544	DNA topoisomerase III, partial [Staphylococcus aureus].	33.49	436	264	13	3	425	4	426	3e-55	206
tr:A9KSH4_CLOPH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.41	697	373	23	3	583	11	697	3e-55	211
rs:WP_021429852	DNA topoisomerase [[Clostridium] bifermentans].	27.16	740	436	27	1	677	1	700	3e-55	211
rs:WP_022614817	DNA topoisomerase [Vibrio nigripulchritudo].	25.81	682	450	18	1	640	1	668	3e-55	212
rs:WP_025161624	DNA topoisomerase [[Clostridium] bifermentans].	27.16	740	436	27	1	677	1	700	3e-55	211
rs:WP_009246241	MULTISPECIES: DNA topoisomerase III [Lachnospiraceae].	27.84	643	388	16	3	579	5	637	3e-55	211
rs:WP_002583310	MULTISPECIES: DNA topoisomerase III [Clostridiales].	27.62	677	380	18	3	578	5	672	3e-55	211
rs:WP_031874330	DNA topoisomerase III, partial [Staphylococcus aureus].	33.49	436	264	13	3	425	4	426	3e-55	206
rs:WP_015056179	DNA topoisomerase III [Staphylococcus aureus].	30.90	547	343	13	3	528	4	536	3e-55	208
rs:WP_016286472	DNA topoisomerase III [Lachnospiraceae bacterium 3-1].	27.98	704	399	26	3	606	5	700	3e-55	211
rs:WP_022076405	DNA topoisomerase III [Firmicutes bacterium CAG:212].	27.48	655	401	20	5	594	7	652	4e-55	211
rs:WP_002370882	DNA topoisomerase, partial [Enterococcus faecium].	28.19	557	357	11	31	553	11	558	4e-55	209
rs:WP_010217635	DNA topoisomerase III [Pseudomonas amygdali].	26.53	735	467	22	1	684	1	713	4e-55	211
rs:WP_035652017	hypothetical protein, partial [Lachnospiraceae bacterium AC3007].	26.24	667	397	19	3	591	5	654	4e-55	211
rs:WP_024858121	DNA topoisomerase III [Ruminococcus albus].	27.69	661	439	18	2	636	3	650	4e-55	211
rs:WP_028603717	hypothetical protein [Ottowia thiooxydans].	26.28	643	408	17	3	591	5	635	4e-55	211
rs:WP_021894879	DNA topoisomerase [Clostridium bolteae CAG:59].	27.79	673	379	20	3	578	5	667	6e-55	210
rs:WP_035314400	DNA topoisomerase III [Clostridium sp. D5].	28.30	675	387	22	5	594	7	669	6e-55	210
rs:WP_011152917	hypothetical protein [Pseudomonas syringae].	26.78	732	469	23	1	684	1	713	7e-55	211
rs:WP_022358423	DNA topoisomerase [Clostridium sp. CAG:43].	25.68	697	391	21	3	578	5	695	7e-55	211
rs:WP_023945960	DNA topoisomerase III [Helicobacter fennelliae].	29.32	614	375	17	1	574	1	595	7e-55	210
rs:WP_026901859	DNA topoisomerase [Peptostreptococcaceae bacterium VA2].	27.28	744	452	26	1	679	1	720	7e-55	211
rs:WP_024651600	DNA topoisomerase III [Pseudomonas syringae].	26.47	733	470	23	1	684	1	713	7e-55	211
rs:WP_020303949	hypothetical protein [Pseudomonas syringae].	26.84	734	466	23	1	684	1	713	7e-55	211
rs:WP_025657742	DNA topoisomerase III [Clostridiales bacterium VE202-21].	27.83	672	394	21	5	594	7	669	7e-55	210
rs:WP_021870156	DNA topoisomerase [Clostridium sp. CAG:7].	27.65	669	393	18	3	587	5	666	7e-55	210
rs:WP_021396176	DNA topoisomerase [Peptoclostridium difficile].	27.24	760	439	30	1	678	1	728	8e-55	211
tr:B0G5U8_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.82	686	400	19	3	594	5	682	8e-55	211
rs:WP_022502109	DNA topoisomerase III [Eubacterium sp. CAG:76].	28.77	664	382	23	5	594	7	653	8e-55	209
rs:WP_008753349	DNA topoisomerase III [Lachnoanaerobaculum saburreum].	27.72	635	393	15	2	578	3	629	9e-55	209
rs:WP_002564358	MULTISPECIES: DNA topoisomerase III [Lachnoclostridium].	27.49	673	381	19	3	578	5	667	9e-55	210
rs:WP_032133874	DNA topoisomerase III [Kingella kingae].	27.80	741	431	26	3	682	5	702	9e-55	210
rs:WP_040015482	DNA topoisomerase III, partial [Dorea formicigenerans].	26.82	686	400	19	3	594	5	682	9e-55	210
rs:WP_032566798	DNA topoisomerase I, partial [Bacteroides fragilis].	30.27	555	347	19	146	684	4	534	9e-55	207
rs:WP_002556105	DNA topoisomerase III [Pseudomonas savastanoi].	26.26	735	469	22	1	684	1	713	1e-54	210
tr:X0NXT2_PHOLE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.88	441	264	10	161	574	51	486	1e-54	207
tr:F7LSI8_9BACE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGN05987.1};	32.78	424	242	12	1	391	1	414	1e-54	204
rs:WP_021424740	DNA topoisomerase [Peptoclostridium difficile].	29.61	672	413	23	3	643	4	646	1e-54	210
rs:WP_042258672	DNA topoisomerase III, partial [Butyrivibrio proteoclasticus].	28.14	629	391	21	3	578	5	625	1e-54	209
rs:WP_012263710	DNA topoisomerase [Bacillus thuringiensis].	28.57	658	412	21	32	655	37	670	1e-54	211
rs:WP_003497037	DNA topoisomerase 3 [[Clostridium] symbiosum].	26.40	712	451	20	3	676	5	681	1e-54	209
rs:WP_042257786	DNA topoisomerase, partial [Butyrivibrio proteoclasticus].	25.93	644	402	16	2	578	4	639	1e-54	209
rs:WP_002574756	DNA topoisomerase III [[Clostridium] bolteae].	27.49	673	381	19	3	578	5	667	1e-54	209
rs:WP_009536236	DNA topoisomerase III [Oribacterium asaccharolyticum].	26.28	647	401	17	2	580	3	641	1e-54	209
rs:WP_044422738	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	26.12	735	470	23	1	684	1	713	1e-54	210
rs:WP_043128703	DNA topoisomerase III, partial [Photobacterium leiognathi].	32.49	437	271	9	161	574	62	497	1e-54	207
tr:V2NIF4_SALET	SubName: Full=Topoisomerase {ECO:0000313|EMBL:ESJ74434.1};	25.74	676	424	14	76	677	7	678	1e-54	209
rs:WP_004367624	DNA topoisomerase TopB, partial [Prevotella nigrescens].	29.74	575	372	15	111	673	1	555	1e-54	207
tr:A8RRB2_CLOBW	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.49	673	381	19	3	578	9	671	1e-54	209
rs:WP_012443177	DNA topoisomerase III [Erwinia tasmaniensis].	26.74	733	469	22	1	683	1	715	1e-54	210
rs:WP_046822078	DNA topoisomerase [Clostridium sp. JC272].	27.42	744	429	30	1	677	1	700	1e-54	210
rs:WP_040343003	DNA topoisomerase III, partial [Bacillus nealsonii].	34.04	376	216	11	3	361	4	364	1e-54	202
rs:WP_009445426	DNA topoisomerase III [Lachnospiraceae bacterium oral taxon 082].	28.66	635	386	16	2	577	3	629	1e-54	209
rs:WP_021403859	DNA topoisomerase [Peptoclostridium difficile].	26.84	760	442	29	1	678	1	728	1e-54	210
rs:WP_009218495	DNA topoisomerase III [Lachnospiraceae oral taxon 107].	27.39	639	392	17	2	578	3	631	1e-54	209
rs:WP_014343770	DNA topoisomerase III [Aliivibrio fischeri].	30.77	507	307	15	1	476	1	494	1e-54	206
rs:WP_016728792	DNA topoisomerase [Peptoclostridium difficile].	26.84	760	442	29	1	678	1	728	1e-54	210
rs:WP_025391090	DNA topoisomerase III [Pseudomonas syringae].	26.78	732	469	23	1	684	1	713	2e-54	209
rs:WP_021406476	DNA topoisomerase [Peptoclostridium difficile].	26.84	760	442	29	1	678	1	728	2e-54	210
rs:WP_004454701	DNA topoisomerase [Peptoclostridium difficile].	26.84	760	442	29	1	678	1	728	2e-54	210
rs:WP_011861544	DNA topoisomerase [Peptoclostridium difficile].	26.84	760	442	29	1	678	1	728	2e-54	210
rs:WP_004276310	DNA topoisomerase III [Campylobacter upsaliensis].	28.94	691	427	22	1	649	1	669	2e-54	209
rs:WP_045761400	DNA topoisomerase III [Xanthomonas albilineans].	27.20	614	404	16	1	587	1	598	2e-54	209
rs:WP_044796831	DNA topoisomerase I [Bacillus cereus].	27.39	712	452	24	3	675	5	690	2e-54	211
rs:WP_022345820	DNA topoisomerase [Clostridium sp. CAG:299].	26.36	664	390	20	3	578	5	657	2e-54	209
rs:WP_034023840	hypothetical protein [Pseudomonas aeruginosa].	25.14	708	474	19	3	668	4	697	2e-54	209
rs:WP_009249295	DNA topoisomerase III [Lachnospiraceae bacterium 5_1_57FAA].	28.07	659	396	22	3	594	5	652	2e-54	209
rs:WP_021413946	DNA topoisomerase [Peptoclostridium difficile].	26.84	760	442	29	1	678	1	728	2e-54	209
rs:WP_021421652	DNA topoisomerase [Peptoclostridium difficile].	26.84	760	442	29	1	678	1	728	2e-54	209
rs:WP_001235769	hypothetical protein [Escherichia coli].	27.36	742	464	22	1	683	1	726	2e-54	209
tr:R9C509_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.04	376	216	11	3	361	4	364	2e-54	202
rs:WP_009897597	DNA topoisomerase [Peptoclostridium difficile].	26.84	760	442	29	1	678	1	728	2e-54	209
rs:WP_021385283	DNA topoisomerase [Peptoclostridium difficile].	27.01	759	442	29	1	678	1	728	2e-54	209
rs:WP_039660485	DNA topoisomerase III, partial [Pantoea sp. MBLJ3].	31.68	464	281	11	143	581	48	500	2e-54	206
rs:WP_046217659	DNA topoisomerase III, partial [Bacillus endophyticus].	28.92	574	330	15	100	646	11	533	2e-54	207
rs:WP_001832808	MULTISPECIES: DNA topoisomerase [Staphylococcus].	27.30	729	457	22	3	679	4	711	2e-54	209
tr:T1CM99_9HELI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.06	616	387	18	1	581	1	601	2e-54	207
rs:WP_006122530	DNA topoisomerase III [Pantoea stewartii].	25.56	763	453	20	2	675	3	739	2e-54	209
rs:WP_046235799	DNA topoisomerase III [Pseudomonas syringae pv. coryli].	26.78	732	469	23	1	684	1	713	2e-54	209
rs:WP_002418951	DNA topoisomerase, partial [Enterococcus faecalis].	35.26	329	186	8	2	321	4	314	2e-54	200
rs:WP_022250918	DNA topoisomerase III [Clostridium nexile CAG:348].	28.22	645	402	20	5	594	7	645	3e-54	208
rs:WP_004066586	DNA topoisomerase III [Eubacterium plexicaudatum].	27.55	646	394	20	3	579	5	645	3e-54	208
rs:WP_026494579	DNA topoisomerase [Butyrivibrio sp. WCD3002].	25.30	759	473	22	2	679	4	749	3e-54	212
rs:WP_021422494	DNA topoisomerase [Peptoclostridium difficile].	26.84	760	442	29	1	678	1	728	3e-54	209
rs:WP_044907008	DNA topoisomerase III [[Clostridium] innocuum].	26.74	718	444	21	3	661	4	698	3e-54	209
rs:WP_003416718	DNA topoisomerase [Peptoclostridium difficile].	27.34	757	442	29	1	678	1	728	3e-54	209
tr:A8SC99_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.60	591	372	16	105	671	18	582	3e-54	207
rs:WP_044310701	DNA topoisomerase III [Pseudomonas syringae].	26.67	735	466	23	1	684	1	713	3e-54	209
rs:WP_002338064	DNA topoisomerase III [Enterococcus faecium].	28.93	605	389	13	103	680	3	593	3e-54	207
rs:WP_032429271	hypothetical protein, partial [Klebsiella pneumoniae].	27.87	732	439	23	1	654	1	721	3e-54	209
rs:WP_034028189	DNA topoisomerase III [Pseudomonas aeruginosa].	26.13	727	472	19	1	680	1	709	3e-54	209
rs:WP_031598161	DNA topoisomerase III [Pseudomonas savastanoi].	26.39	735	468	23	1	684	1	713	3e-54	209
rs:WP_040227551	DNA topoisomerase III, partial [Bhargavaea cecembensis].	32.61	460	280	13	3	444	5	452	3e-54	204
rs:WP_003407083	DNA topoisomerase III [Pseudomonas syringae].	26.33	733	472	21	1	684	1	714	4e-54	208
rs:WP_021419380	DNA topoisomerase [Peptoclostridium difficile].	26.84	760	442	29	1	678	1	728	4e-54	208
rs:WP_019842535	hypothetical protein [Escherichia coli].	26.86	741	469	20	1	683	1	726	4e-54	208
rs:WP_003430842	DNA topoisomerase [Peptoclostridium difficile].	26.84	760	442	29	1	678	1	728	4e-54	208
rs:WP_008153388	hypothetical protein, partial [Parabacteroides johnsonii].	30.37	540	336	19	161	684	2	517	4e-54	205
rs:WP_025487227	DNA topoisomerase III [Clostridiales bacterium VE202-28].	26.00	673	388	16	3	578	5	664	4e-54	208
tr:D7GWX3_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.14	678	365	20	3	578	5	655	4e-54	207
rs:WP_016214645	DNA topoisomerase III [Eubacterium sp. 14-2].	27.15	674	382	22	3	579	5	666	5e-54	208
rs:WP_021560353	hypothetical protein [Escherichia coli].	27.20	739	469	19	1	683	1	726	5e-54	208
rs:WP_000280351	hypothetical protein [Bacillus cereus].	26.06	729	456	23	1	661	1	714	5e-54	208
rs:WP_004842675	DNA topoisomerase III [[Ruminococcus] gnavus].	28.24	648	395	22	5	594	7	642	5e-54	207
rs:WP_022037158	DNA topoisomerase III [Ruminococcus gnavus CAG:126].	28.09	648	396	21	5	594	7	642	5e-54	207
rs:WP_041473510	hypothetical protein, partial [Bifidobacterium breve].	26.72	655	406	16	84	677	4	645	5e-54	207
rs:WP_021425657	DNA topoisomerase [Peptoclostridium difficile].	26.71	760	443	29	1	678	1	728	5e-54	208
rs:WP_028856605	DNA topoisomerase III [Psychrilyobacter atlanticus].	28.45	717	447	24	2	687	3	684	5e-54	207
tr:J8HJV3_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.01	586	367	18	3	558	5	571	6e-54	206
rs:WP_044798599	DNA topoisomerase I [Bacillus thuringiensis].	28.80	677	435	21	32	679	37	695	6e-54	209
rs:WP_016284600	DNA topoisomerase III [Lachnospiraceae bacterium A4].	29.16	583	371	16	112	671	1	564	6e-54	206
rs:WP_009893600	DNA topoisomerase [Peptoclostridium difficile].	26.84	760	442	29	1	678	1	728	6e-54	208
rs:WP_021985184	DNA topoisomerase [Clostridium sp. CAG:127].	27.48	644	393	20	3	578	4	641	7e-54	207
rs:WP_003464782	DNA topoisomerase III [Clostridium perfringens].	29.71	717	440	22	2	680	3	693	7e-54	207
rs:WP_033337307	hypothetical protein, partial [Thioalkalivibrio thiocyanodenitrificans].	31.44	439	271	14	2	425	5	428	7e-54	202
rs:WP_002502793	DNA topoisomerase [Staphylococcus epidermidis].	27.58	736	446	25	3	679	4	711	7e-54	207
rs:WP_033066679	hypothetical protein [Clostridium botulinum].	28.65	705	448	22	2	677	3	681	8e-54	208
rs:WP_000520757	DNA topoisomerase I [Bacillus cereus].	28.17	678	437	20	32	679	37	694	8e-54	208
rs:WP_044322592	DNA topoisomerase III, partial [Pseudomonas amygdali].	29.32	607	378	14	1	565	1	598	8e-54	206
rs:WP_031893288	DNA topoisomerase [Staphylococcus aureus].	27.16	729	458	22	3	679	4	711	8e-54	207
rs:WP_023924313	DNA topoisomerase III [[Ruminococcus] gnavus].	28.09	648	396	21	5	594	7	642	8e-54	207
rs:WP_021426560	DNA topoisomerase [Peptoclostridium difficile].	26.84	760	442	29	1	678	1	728	9e-54	207
rs:WP_021375895	DNA topoisomerase [Peptoclostridium difficile].	26.84	760	442	29	1	678	1	728	9e-54	207
tr:W1HVM3_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.57	414	247	13	190	581	1	408	9e-54	202
rs:WP_040109967	hypothetical protein [Clostridium botulinum].	28.65	705	448	22	2	677	3	681	9e-54	208
rs:WP_017070755	DNA topoisomerase III, partial [Vibrio crassostreae].	30.04	476	295	11	2	445	3	472	9e-54	203
rs:WP_031388728	DNA topoisomerase III, partial [Desulfonatronum thiodismutans].	27.74	638	383	20	3	580	4	623	1e-53	206
rs:WP_013499826	DNA topoisomerase III [Ruminococcus albus].	28.08	666	430	22	2	636	3	650	1e-53	207
rs:WP_024038076	DNA topoisomerase [Intestinibacter bartlettii].	26.96	753	441	26	1	679	1	718	1e-53	207
rs:WP_007287786	DNA topoisomerase III [Intestinibacter bartlettii].	26.96	753	441	26	1	679	1	718	1e-53	207
rs:WP_023180744	topoisomerase [Salmonella enterica].	25.66	760	456	21	2	675	3	739	1e-53	207
rs:WP_008824364	hypothetical protein, partial [Prevotella histicola].	32.32	427	259	11	1	414	2	411	1e-53	202
rs:WP_045853554	DNA topoisomerase III [Raoultella terrigena].	28.83	718	444	21	1	670	1	699	1e-53	207
rs:WP_007253354	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	25.71	735	473	22	1	684	1	713	1e-53	207
rs:WP_031667774	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	26.00	727	473	18	1	680	1	709	1e-53	207
rs:WP_008271225	MULTISPECIES: DNA topoisomerase [Enterococcus].	28.60	605	391	13	103	680	3	593	1e-53	205
rs:WP_022341006	DNA topoisomerase III [Roseburia sp. CAG:309].	27.12	660	388	20	2	579	4	652	1e-53	206
rs:WP_004606705	DNA topoisomerase III [[Clostridium] scindens].	27.57	642	390	19	3	578	5	637	1e-53	206
rs:WP_024854553	DNA topoisomerase III [[Ruminococcus] gnavus].	28.48	632	383	21	5	578	7	627	1e-53	206
rs:WP_022338804	DNA topoisomerase [Clostridium sp. CAG:433].	28.39	722	452	23	1	684	1	695	1e-53	207
tr:W1H5Z8_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.57	414	247	13	190	581	1	408	1e-53	202
rs:WP_006780354	DNA topoisomerase III [[Clostridium] hathewayi].	27.49	684	395	22	3	594	5	679	1e-53	206
rs:WP_036057673	hypothetical protein, partial [Burkholderia mallei].	29.03	596	359	21	3	561	4	572	1e-53	204
rs:WP_002343079	DNA topoisomerase III [Enterococcus faecium].	28.76	605	390	13	103	680	3	593	1e-53	205
rs:WP_013085583	conjugal transfer protein TraE [Neisseria gonorrhoeae].	26.80	653	421	16	2	614	3	638	1e-53	207
rs:WP_039311041	DNA topoisomerase III, partial [Pectobacterium atrosepticum].	26.52	724	453	19	1	673	1	696	1e-53	207
rs:WP_016218703	DNA topoisomerase III [Dorea sp. 5-2].	27.11	653	391	20	3	578	5	649	1e-53	206
rs:WP_004849107	DNA topoisomerase III [Coprococcus eutactus].	28.44	640	386	23	3	582	4	631	1e-53	206
rs:WP_026651907	DNA topoisomerase III [Butyrivibrio proteoclasticus].	27.65	680	379	19	2	580	5	672	1e-53	207
rs:WP_002316086	DNA topoisomerase [Enterococcus faecium].	28.60	605	391	13	103	680	3	593	1e-53	205
rs:WP_024668846	DNA topoisomerase III, partial [Pseudomonas syringae].	26.55	693	444	21	1	647	1	674	1e-53	206
rs:WP_029485981	DNA topoisomerase [Enterococcus faecium].	28.76	605	390	13	103	680	3	593	1e-53	205
rs:WP_004845710	DNA topoisomerase III [[Ruminococcus] torques].	28.36	670	394	21	2	594	4	664	1e-53	206
rs:WP_010723882	DNA topoisomerase III [Enterococcus faecium].	28.76	605	390	13	103	680	3	593	1e-53	205
rs:WP_038810986	DNA topoisomerase [Enterococcus faecium].	28.60	605	391	13	103	680	3	593	1e-53	205
rs:WP_022618531	DNA topoisomerase type IA [Peptoclostridium difficile].	26.58	760	444	29	1	678	1	728	1e-53	207
rs:WP_042735322	DNA topoisomerase III [Lachnospiraceae bacterium TWA4].	28.59	633	389	19	3	580	4	628	1e-53	206
rs:WP_003458909	DNA topoisomerase III [Clostridium perfringens].	29.38	725	432	25	2	680	3	693	2e-53	206
rs:WP_008716160	DNA topoisomerase III [Clostridiales bacterium 1_7_47FAA].	25.85	673	389	16	3	578	5	664	2e-53	206
tr:U2QF86_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.60	605	391	13	103	680	3	593	2e-53	205
rs:WP_021943206	DNA topoisomerase [Clostridium sp. CAG:264].	28.68	638	379	20	3	578	4	627	2e-53	206
rs:WP_016225184	DNA topoisomerase III [Lachnospiraceae bacterium 3-2].	27.56	664	380	22	3	578	5	655	2e-53	206
rs:WP_003321296	DNA topoisomerase [Bacillus alcalophilus].	27.41	715	471	20	1	679	1	703	2e-53	206
rs:WP_031922917	DNA topoisomerase III, partial [Staphylococcus aureus].	29.83	580	371	14	3	560	4	569	2e-53	204
rs:WP_021628044	DNA topoisomerase, partial [Capnocytophaga sp. oral taxon 863].	31.18	526	320	16	85	584	1	510	2e-53	202
rs:WP_009756925	DNA topoisomerase III [Lachnospiraceae bacterium 2_1_46FAA].	29.06	640	378	23	5	579	7	635	2e-53	206
rs:WP_002336691	DNA topoisomerase III [Enterococcus faecium].	28.93	605	389	14	103	680	3	593	2e-53	204
tr:T0XU08_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.09	431	272	6	173	581	1	428	2e-53	202
rs:WP_033864034	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	28.90	557	351	16	108	629	2	548	2e-53	204
rs:WP_035102953	DNA topoisomerase III, partial [Coprococcus sp. HPP0074].	35.31	371	222	9	1	365	1	359	2e-53	202
rs:WP_016121209	DNA topoisomerase III [Bacillus cereus].	27.53	701	461	22	3	673	5	688	2e-53	207
tr:F8F8M0_PAEMK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.84	620	368	24	3	577	4	601	2e-53	209
tr:A0A0C5PL74_SHIFL	SubName: Full=Strain 072 plasmid pSF07202, complete sequence {ECO:0000313|EMBL:AJQ17353.1};	28.76	671	426	17	44	673	4	663	2e-53	206
rs:WP_000520758	DNA topoisomerase I [Bacillus thuringiensis].	28.06	670	448	18	32	679	37	694	2e-53	207
rs:WP_022059536	DNA topoisomerase [Coprococcus eutactus CAG:665].	28.44	640	386	23	3	582	4	631	2e-53	206
rs:WP_017876401	hypothetical protein [Janthinobacterium sp. CG3].	27.16	637	404	21	1	592	1	622	2e-53	206
rs:WP_012008596	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	28.06	670	448	18	32	679	37	694	2e-53	207
tr:F7JRL0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	35.31	371	222	9	1	365	1	359	2e-53	202
rs:WP_022272651	DNA topoisomerase III [Clostridium sp. CAG:58].	26.37	675	377	20	3	578	5	658	2e-53	206
tr:W4V5H9_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.74	482	290	15	170	627	2	468	2e-53	203
tr:G5Q3L3_SALMO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.57	436	263	13	166	581	3	427	3e-53	202
rs:WP_025755768	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	27.94	698	432	24	1	646	1	679	3e-53	206
tr:S2YZQ0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	35.31	371	222	9	1	365	1	359	3e-53	202
rs:WP_038267162	DNA topoisomerase III [Xenorhabdus cabanillasii].	26.68	671	416	17	79	677	10	676	3e-53	206
rs:WP_032469697	DNA topoisomerase III, partial [Vibrio cholerae].	31.50	454	269	9	161	581	62	506	3e-53	203
rs:WP_009242248	MULTISPECIES: DNA topoisomerase III [unclassified Lachnospiraceae].	28.36	670	394	21	2	594	4	664	3e-53	205
tr:C3DWP7_BACTS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.06	670	448	18	32	679	37	694	3e-53	207
rs:WP_002349886	DNA topoisomerase, partial [Enterococcus faecium].	27.36	658	421	16	54	667	5	649	3e-53	205
rs:WP_026487967	DNA topoisomerase III [Butyrivibrio sp. XBB1001].	28.51	677	375	22	5	580	8	676	3e-53	206
rs:WP_035642014	DNA topoisomerase III [Lachnospiraceae bacterium FE2018].	26.53	701	388	21	3	583	6	699	3e-53	206
rs:WP_022072193	DNA topoisomerase III [Clostridium bartlettii CAG:1329].	26.56	753	444	25	1	679	1	718	3e-53	206
tr:W1DKN2_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.48	657	400	18	89	678	28	668	4e-53	205
rs:WP_034212370	DNA topoisomerase III [Lachnoanaerobaculum sp. MSX33].	27.90	638	391	18	2	578	3	632	4e-53	205
rs:WP_023208305	DNA topoisomerase III [Salmonella enterica].	28.47	720	449	21	1	673	1	701	4e-53	206
rs:WP_033910164	conjugal transfer protein TraE [Neisseria gonorrhoeae].	26.65	653	422	16	2	614	3	638	4e-53	206
rs:WP_047334070	hypothetical protein [Enterococcus cecorum].	25.86	723	452	23	3	673	4	694	4e-53	205
rs:WP_022438332	DNA topoisomerase III [Clostridium sp. CAG:411].	28.42	651	378	22	5	578	7	646	4e-53	205
rs:WP_005539987	DNA topoisomerase III [Johnsonella ignava].	27.38	683	373	22	3	578	4	670	4e-53	205
tr:D4JQ77_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.34	621	388	18	2	579	18	624	4e-53	206
tr:C2UN45_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	25.93	725	454	23	5	661	1	710	4e-53	206
rs:WP_038352446	hypothetical protein, partial [Eubacterium limosum].	27.93	666	413	24	3	627	4	643	5e-53	204
rs:WP_035518992	DNA topoisomerase, partial [Burkholderia sp. Ch1-1].	28.60	535	324	15	3	496	5	522	5e-53	202
rs:WP_030032216	hypothetical protein [Clostridium botulinum].	28.51	705	449	22	2	677	3	681	5e-53	206
rs:WP_031620292	DNA topoisomerase III, partial [Salmonella enterica].	29.53	596	377	14	1	561	1	588	6e-53	203
rs:WP_022465005	DNA topoisomerase III [Clostridium sp. CAG:277].	27.14	667	389	20	2	578	4	663	6e-53	204
rs:WP_022203700	DNA topoisomerase [Eubacterium sp. CAG:248].	28.12	665	376	22	5	587	7	651	6e-53	204
rs:WP_023041758	hypothetical protein [Fusobacterium nucleatum].	27.67	730	443	25	1	680	1	695	6e-53	205
rs:WP_008268666	DNA topoisomerase [Enterococcus sp. GMD1E].	28.43	605	392	13	103	680	3	593	7e-53	203
rs:WP_035478371	hypothetical protein, partial [Burkholderia phenoliruptrix].	28.17	600	367	19	3	562	4	579	7e-53	202
tr:Q3EKS2_BACTI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.00	403	252	8	1	386	1	402	7e-53	198
rs:WP_031849828	hypothetical protein [Vibrio parahaemolyticus].	28.15	604	383	18	3	570	4	592	7e-53	203
rs:WP_006775974	DNA topoisomerase III [[Clostridium] hathewayi].	25.76	656	402	15	3	578	5	655	8e-53	204
rs:WP_042762169	hypothetical protein [Vibrio parahaemolyticus].	28.15	604	383	18	3	570	4	592	8e-53	203
rs:WP_021562493	hypothetical protein [Escherichia coli].	26.27	769	460	25	1	673	1	758	8e-53	205
tr:C9C9G9_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.93	629	400	17	82	673	2	620	8e-53	204
tr:D4LZE7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.58	689	389	24	5	594	7	684	8e-53	204
rs:WP_003445085	DNA topoisomerase III [Clostridium pasteurianum].	30.43	608	369	21	2	574	3	591	8e-53	203
rs:WP_011282541	DNA topoisomerase III [Pseudomonas savastanoi].	26.12	735	470	23	1	684	1	713	8e-53	204
rs:WP_010742428	DNA topoisomerase III [Enterococcus malodoratus].	28.76	605	390	13	103	680	3	593	8e-53	202
rs:WP_032072421	DNA topoisomerase III [Clostridium botulinum].	28.51	705	449	22	2	677	3	681	9e-53	205
rs:WP_021729338	DNA topoisomerase 1 [Bacillus thuringiensis].	28.08	673	444	19	32	679	37	694	9e-53	205
rs:WP_004602163	DNA topoisomerase III [[Eubacterium] cellulosolvens].	26.66	709	406	24	3	608	5	702	9e-53	204
rs:WP_018591436	DNA topoisomerase [Terrisporobacter glycolicus].	26.52	739	461	25	1	679	1	717	1e-52	204
rs:WP_025531786	DNA topoisomerase III [[Clostridium] hathewayi].	25.91	656	401	16	3	578	5	655	1e-52	204
rs:WP_001235773	MULTISPECIES: DNA topoisomerase III [Escherichia].	27.92	702	427	26	1	646	1	679	1e-52	204
rs:WP_009272259	DNA topoisomerase III [Erysipelotrichaceae bacterium 3_1_53].	27.21	680	428	19	3	638	4	660	1e-52	204
rs:WP_029491115	DNA topoisomerase III [Fusobacterium hwasookii].	30.76	634	368	21	1	595	1	602	1e-52	202
rs:WP_031669330	hypothetical protein [Listeria monocytogenes].	27.14	711	464	22	3	673	4	700	1e-52	204
tr:A0A0B7JB60_PHOPO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.37	448	269	11	161	581	70	510	1e-52	201
rs:WP_022032138	DNA topoisomerase III [Clostridium hathewayi CAG:224].	25.76	656	402	15	3	578	5	655	1e-52	204
rs:WP_035613615	DNA topoisomerase, partial [Lachnospiraceae bacterium COE1].	26.94	657	390	19	2	580	4	648	1e-52	203
rs:WP_041690182	hypothetical protein, partial [Eubacterium limosum].	28.05	663	416	24	3	627	4	643	1e-52	203
rs:WP_025775433	hypothetical protein [Clostridium botulinum].	29.58	710	435	25	2	677	3	681	1e-52	204
rs:WP_046602256	DNA topoisomerase III [Pseudomonas aeruginosa].	25.86	727	474	18	1	680	1	709	1e-52	204
rs:WP_021651108	DNA topoisomerase III [Blautia sp. KLE 1732].	26.59	662	404	23	3	594	5	654	1e-52	203
rs:WP_036796284	DNA topoisomerase III, partial [Photobacterium phosphoreum].	32.37	448	269	11	161	581	58	498	1e-52	201
rs:WP_016128424	DNA topoisomerase III [Bacillus cereus].	27.16	696	434	19	3	655	5	670	1e-52	205
rs:XP_004334075	DNA topoisomerase [Acanthamoeba castellanii str. Neff].	26.21	782	428	29	41	684	298	1068	1e-52	207
rs:WP_012300871	hypothetical protein [Clostridium botulinum].	29.76	709	435	25	2	677	3	681	1e-52	204
rs:WP_021960535	DNA topoisomerase III [Butyrivibrio crossotus CAG:259].	26.44	662	414	18	3	600	4	656	1e-52	203
rs:WP_043992340	DNA topoisomerase III, partial [Vibrio cholerae].	31.50	454	269	10	161	581	35	479	1e-52	200
rs:WP_045715460	DNA topoisomerase III, partial [Salmonella enterica].	32.61	414	255	11	188	581	3	412	1e-52	199
rs:WP_042275571	DNA topoisomerase [Clostridium sp. 01].	26.95	742	454	27	1	679	1	717	2e-52	204
rs:WP_034064609	DNA topoisomerase III [Pseudomonas aeruginosa].	26.10	728	471	20	1	680	1	709	2e-52	204
rs:WP_021107261	type I topoisomease [Clostridium botulinum].	29.44	710	436	25	2	677	3	681	2e-52	204
rs:WP_027870499	DNA topoisomerase III [[Eubacterium] cellulosolvens].	26.45	707	410	23	3	608	5	702	2e-52	203
rs:WP_031672442	hypothetical protein [Listeria monocytogenes].	27.14	711	464	22	3	673	4	700	2e-52	203
rs:WP_002604273	DNA topoisomerase III [[Clostridium] hathewayi].	25.91	656	401	16	3	578	5	655	2e-52	203
rs:WP_001681355	DNA topoisomerase III, partial [Salmonella enterica].	30.87	460	281	16	1	431	1	452	2e-52	198
rs:WP_009534223	DNA topoisomerase III [Oribacterium parvum].	27.54	650	389	20	2	580	3	641	2e-52	202
rs:WP_005603390	DNA topoisomerase III [Butyrivibrio crossotus].	26.44	662	414	18	3	600	4	656	2e-52	202
tr:V8L219_XYLFS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.40	574	364	14	89	629	34	593	2e-52	202
rs:WP_035778518	DNA topoisomerase III [Butyrivibrio sp. MC2013].	27.09	683	388	20	2	580	3	679	2e-52	203
rs:WP_002609437	DNA topoisomerase III [[Clostridium] innocuum].	26.74	718	444	21	3	661	4	698	2e-52	203
rs:WP_002193616	DNA topoisomerase I [Bacillus cereus].	27.50	709	451	20	3	673	5	688	2e-52	204
rs:WP_007591669	DNA topoisomerase III [Lachnoanaerobaculum sp. OBRC5-5].	27.74	638	392	18	2	578	3	632	2e-52	202
rs:WP_008403089	DNA topoisomerase III [Clostridium sp. L2-50].	27.99	636	386	18	3	578	4	627	3e-52	202
rs:WP_023039176	hypothetical protein [Fusobacterium nucleatum].	27.83	715	461	22	1	680	1	695	3e-52	203
tr:F2LSE5_BURGS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.27	638	388	19	3	581	7	627	3e-52	203
rs:WP_032136827	DNA topoisomerase [Kingella sp. Sch538].	25.45	719	462	22	3	677	5	693	3e-52	203
rs:WP_011989128	hypothetical protein [Clostridium kluyveri].	27.64	709	449	22	1	673	1	681	3e-52	203
rs:WP_044153114	hypothetical protein [Salinibacillus aidingensis].	27.73	642	399	20	43	630	45	675	3e-52	203
rs:WP_025643309	DNA topoisomerase III [[Clostridium] scindens].	28.19	642	386	21	3	578	5	637	3e-52	202
rs:WP_045135956	DNA topoisomerase, partial [Enterococcus faecium].	28.34	614	379	18	108	675	2	600	3e-52	201
rs:WP_042987872	DNA topoisomerase III [Vibrio cholerae].	27.71	729	451	23	1	672	1	710	3e-52	203
rs:WP_022223423	DNA topoisomerase III [Clostridium sp. CAG:253].	28.33	653	382	20	3	578	5	648	3e-52	202
rs:WP_012062393	DNA topoisomerase III [Alkaliphilus metalliredigens].	27.26	763	465	22	3	680	5	762	3e-52	203
rs:WP_002844059	DNA topoisomerase [Peptostreptococcus anaerobius].	26.87	707	412	24	1	636	1	673	3e-52	203
tr:C0B625_9FIRM	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:EEG91159.1};	35.03	334	182	8	1	321	1	312	3e-52	194
rs:WP_023249656	DNA topoisomerase III, partial [Salmonella enterica].	32.94	419	244	16	1	390	1	411	3e-52	197
rs:WP_024167399	DNA topoisomerase III, partial [Escherichia coli].	28.72	679	432	17	36	673	1	668	3e-52	202
rs:WP_021653369	DNA topoisomerase III [Clostridiales bacterium oral taxon 876].	27.58	747	404	26	2	649	4	712	3e-52	203
rs:WP_034070008	DNA topoisomerase III [Pseudomonas aeruginosa].	25.76	726	478	18	1	680	1	711	3e-52	203
rs:WP_012344603	DNA topoisomerase III [Clostridium botulinum].	30.23	612	365	20	2	574	3	591	3e-52	201
rs:WP_007156047	DNA topoisomerase III [Oribacterium sinus].	26.52	660	394	18	3	580	12	662	3e-52	202
rs:WP_029503437	DNA topoisomerase III [Lachnoclostridium phytofermentans].	27.52	694	383	22	3	583	5	691	3e-52	202
rs:WP_041193069	DNA topoisomerase III, partial [Candidatus Profftella armatura].	28.59	654	405	19	3	610	5	642	3e-52	203
rs:WP_022118909	DNA topoisomerase III [Firmicutes bacterium CAG:56].	27.79	637	397	19	2	580	3	634	3e-52	202
tr:F9Y0V9_BIFBU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.07	639	394	17	98	677	7	632	3e-52	202
tr:S5R840_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.59	654	405	19	3	610	5	642	3e-52	203
rs:WP_012952161	DNA topoisomerase III [Listeria monocytogenes].	27.29	711	463	22	3	673	4	700	3e-52	202
rs:WP_041937893	DNA topoisomerase III, partial [Klebsiella pneumoniae].	26.04	718	465	19	1	673	1	697	4e-52	202
rs:WP_000520744	DNA topoisomerase I [Bacillus cereus].	27.57	711	448	22	3	673	5	688	4e-52	204
rs:WP_045716702	DNA topoisomerase III, partial [Salmonella enterica].	32.94	419	244	16	1	390	1	411	4e-52	197
rs:WP_022463020	DNA topoisomerase III [Blautia sp. CAG:37].	27.86	646	384	23	3	578	5	638	4e-52	202
rs:WP_021904993	DNA topoisomerase III [Clostridium sp. CAG:81].	26.55	678	369	19	3	578	5	655	4e-52	202
rs:WP_042165951	DNA topoisomerase III [Pseudomonas aeruginosa].	25.96	728	472	20	1	680	1	709	4e-52	202
rs:WP_033949820	DNA topoisomerase III [Pseudomonas aeruginosa].	25.96	728	472	20	1	680	1	709	4e-52	202
rs:WP_020956887	DNA topoisomerase [Klebsiella pneumoniae].	26.04	718	465	19	1	673	1	697	4e-52	203
rs:WP_004278181	DNA topoisomerase III [Campylobacter upsaliensis].	27.77	641	415	18	1	610	1	624	5e-52	202
tr:C7H3L1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.28	381	241	9	29	399	12	385	5e-52	198
rs:WP_027430564	DNA topoisomerase III [Lachnospira multipara].	27.55	646	387	18	3	578	5	639	5e-52	201
rs:WP_008816880	MULTISPECIES: DNA topoisomerase III [Clostridiales].	26.74	718	444	21	3	661	4	698	5e-52	202
rs:WP_000520743	DNA topoisomerase I [Bacillus cereus].	28.17	717	436	25	3	673	5	688	5e-52	203
tr:A0A0C8ZUT9_SALTI	SubName: Full=TopB_3 protein {ECO:0000313|EMBL:CEU15733.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEU15733.1};	28.46	671	428	17	44	673	4	663	5e-52	201
rs:WP_033630599	DNA topoisomerase, partial [Enterococcus faecium].	28.43	605	372	18	117	675	4	593	6e-52	200
tr:C7UVJ8_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.43	605	372	18	117	675	16	605	6e-52	200
rs:WP_021368817	DNA topoisomerase, partial [Peptoclostridium difficile].	37.15	323	177	8	1	315	1	305	6e-52	192
rs:WP_000520742	hypothetical protein [Bacillus cereus].	27.55	715	455	21	3	679	5	694	6e-52	203
rs:WP_039698954	hypothetical protein [Clostridium botulinum].	28.23	705	451	23	2	677	3	681	6e-52	202
rs:WP_047338920	hypothetical protein [Enterococcus cecorum].	25.73	723	453	23	3	673	4	694	6e-52	202
rs:WP_002845103	DNA topoisomerase [Peptostreptococcus anaerobius].	26.73	707	413	24	1	636	1	673	7e-52	202
tr:T4NA99_PEPDI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	25.81	713	469	17	1	668	1	698	7e-52	202
rs:WP_044963946	DNA topoisomerase III [Clostridiaceae bacterium MS3].	28.44	668	374	24	3	578	5	660	7e-52	201
rs:WP_041348767	DNA topoisomerase [Clostridium botulinum].	30.23	612	365	20	2	574	3	591	7e-52	200
rs:WP_029103745	hypothetical protein [Moraxella caprae].	28.59	675	396	21	1	614	1	650	7e-52	202
rs:WP_032887862	DNA topoisomerase [Fusobacterium nucleatum].	30.71	609	359	18	1	570	1	585	8e-52	200
rs:WP_019595521	MULTISPECIES: DNA topoisomerase [Peptostreptococcus].	26.73	707	413	24	1	636	1	673	8e-52	202
rs:WP_012099617	DNA topoisomerase III [Clostridium botulinum].	30.39	612	364	20	2	574	3	591	8e-52	200
rs:WP_046438492	DNA topoisomerase III, partial [Ruminococcus sp. UNK.MGS-30].	35.19	324	192	8	3	321	4	314	8e-52	193
rs:WP_029675935	MULTISPECIES: DNA topoisomerase, partial [Bacilli].	28.43	605	372	18	117	675	4	593	8e-52	200
rs:WP_016359756	MULTISPECIES: DNA topoisomerase III [Clostridiales].	28.10	669	375	23	3	578	5	660	8e-52	201
rs:WP_004460131	DNA topoisomerase III [Clostridium perfringens].	29.43	717	442	22	2	680	3	693	9e-52	201
rs:WP_025774955	DNA topoisomerase III [Clostridium botulinum].	30.39	612	364	20	2	574	3	591	9e-52	200
rs:WP_003358661	DNA topoisomerase III [Clostridium botulinum].	30.43	608	369	19	2	574	3	591	9e-52	200
rs:WP_042007418	hypothetical protein [Capnocytophaga canimorsus].	28.84	704	436	22	3	666	4	682	9e-52	201
rs:WP_042108034	DNA topoisomerase III, partial [Escherichia coli].	30.50	459	282	16	1	430	1	451	9e-52	196
rs:WP_034319070	DNA topoisomerase III, partial [Helicobacter trogontum].	28.53	624	377	15	1	574	1	605	9e-52	200
rs:WP_045539673	DNA topoisomerase [Clostridium botulinum].	30.43	608	369	19	2	574	3	591	9e-52	200
rs:WP_038308316	DNA topoisomerase III, partial [Kingella kingae].	27.09	716	431	25	22	682	7	686	9e-52	201
rs:WP_035628096	DNA topoisomerase III [Lachnospiraceae bacterium C6A11].	26.41	674	403	21	2	590	3	668	1e-51	201
tr:F0Z4H4_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.04	649	374	21	31	594	17	657	1e-51	201
rs:WP_005681887	DNA topoisomerase I [Bacteroides caccae].	25.54	607	406	15	85	680	37	608	1e-51	200
rs:WP_011949064	DNA topoisomerase [Clostridium botulinum].	30.43	608	369	19	2	574	3	591	1e-51	200
rs:WP_016105662	DNA topoisomerase III [Bacillus cereus].	27.48	706	455	19	3	673	5	688	1e-51	202
rs:WP_002328357	DNA topoisomerase III [Enterococcus faecium].	30.71	495	317	9	103	581	3	487	1e-51	197
rs:WP_031599028	DNA topoisomerase III, partial [Pseudomonas savastanoi].	26.90	658	417	20	1	611	1	641	1e-51	200
rs:WP_005798105	DNA topoisomerase I [Bacteroides fragilis].	25.58	606	407	15	85	680	37	608	1e-51	200
rs:WP_041701982	DNA topoisomerase III [Gottschalkia acidurici].	29.04	644	382	19	3	580	5	639	1e-51	201
rs:WP_000280352	hypothetical protein [Bacillus cereus].	26.37	728	455	23	1	661	1	714	1e-51	201
rs:WP_033981023	DNA topoisomerase III [Pseudomonas aeruginosa].	26.19	733	466	20	1	680	1	711	1e-51	201
rs:WP_002356083	DNA topoisomerase [Enterococcus faecium].	30.71	495	317	9	103	581	3	487	1e-51	197
rs:WP_016102507	DNA topoisomerase III [Bacillus cereus].	27.54	708	452	21	3	673	5	688	1e-51	202
rs:WP_025443192	hypothetical protein [Vibrio parahaemolyticus].	27.81	604	385	18	3	570	4	592	1e-51	199
rs:WP_031555562	DNA topoisomerase III [Lachnospira multipara].	27.45	652	390	21	3	580	5	647	1e-51	200
rs:WP_002341369	DNA topoisomerase III [Enterococcus faecium].	30.71	495	317	9	103	581	3	487	1e-51	197
rs:WP_002307507	DNA topoisomerase [Enterococcus faecium].	30.71	495	317	9	103	581	3	487	1e-51	197
tr:K0B0G9_CLOA9	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.04	644	382	19	3	580	9	643	1e-51	201
rs:WP_022418595	DNA topoisomerase [Acidiphilium sp. CAG:727].	27.21	713	445	21	1	673	1	679	1e-51	201
tr:U2KVD6_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.25	496	300	14	200	673	1	477	1e-51	197
rs:WP_023567376	DNA topoisomerase III, partial [Escherichia coli].	32.46	419	246	16	1	390	1	411	1e-51	196
rs:WP_032848987	DNA topoisomerase III, partial [Mannheimia haemolytica].	29.61	456	287	12	1	430	1	448	1e-51	196
rs:WP_029493414	DNA topoisomerase III [Fusobacterium hwasookii].	30.71	609	359	18	1	570	1	585	1e-51	199
rs:WP_033606902	DNA topoisomerase, partial [Enterococcus faecium].	28.43	605	372	18	117	675	4	593	1e-51	199
tr:A0A073ICB2_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KEJ87404.1};	29.14	549	318	15	157	647	26	561	1e-51	198
rs:WP_027438062	DNA topoisomerase III [Lachnospira multipara].	27.45	652	390	22	3	580	5	647	2e-51	200
rs:WP_032948603	DNA topoisomerase I, partial [Bacteroides vulgatus].	32.77	415	243	11	1	394	1	400	2e-51	196
rs:WP_046960179	DNA topoisomerase I [Bacillus cereus].	27.67	712	446	23	3	673	5	688	2e-51	202
rs:WP_013272546	DNA topoisomerase III [[Clostridium] saccharolyticum].	25.88	680	393	18	3	578	5	677	2e-51	200
rs:WP_033946171	DNA topoisomerase III [Pseudomonas aeruginosa].	26.00	727	472	19	1	680	1	708	2e-51	201
rs:WP_025966435	DNA topoisomerase I [Bacillus cereus].	28.05	713	442	25	3	673	5	688	2e-51	201
rs:WP_013555135	DNA topoisomerase [Bacillus thuringiensis].	29.79	611	377	21	93	664	1	598	2e-51	199
rs:WP_011986253	DNA topoisomerase [Clostridium botulinum].	30.43	608	369	19	2	574	3	591	2e-51	199
rs:WP_034558194	DNA topoisomerase, partial [Carnobacterium gallinarum].	28.26	605	373	18	117	675	4	593	2e-51	199
rs:WP_000520726	DNA topoisomerase I [Bacillus cereus].	27.85	711	446	23	3	673	5	688	2e-51	201
tr:R6P0H2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.56	689	396	23	5	594	7	684	2e-51	200
rs:WP_005909733	DNA topoisomerase III [Fusobacterium nucleatum].	27.69	715	462	22	1	680	1	695	2e-51	200
rs:WP_031825716	DNA topoisomerase III, partial [Staphylococcus aureus].	28.97	580	378	15	68	625	1	568	3e-51	198
rs:WP_024933790	DNA topoisomerase III [Clostridium botulinum].	30.23	612	365	20	2	574	3	591	3e-51	199
rs:WP_044133343	DNA topoisomerase III, partial [Bacteroides fragilis].	31.97	416	244	10	1	385	1	408	3e-51	194
rs:WP_044727381	DNA topoisomerase III [Pseudomonas aeruginosa].	26.06	733	467	20	1	680	1	711	3e-51	200
rs:WP_015958118	DNA topoisomerase III [Clostridium botulinum].	30.07	612	366	20	2	574	3	591	3e-51	198
rs:WP_033059191	MULTISPECIES: DNA topoisomerase III [Clostridium].	29.90	612	367	20	2	574	3	591	3e-51	198
rs:WP_025867914	DNA topoisomerase I, partial [Bacteroides nordii].	33.33	390	226	10	1	369	1	377	3e-51	193
rs:WP_012703748	DNA topoisomerase III [Clostridium botulinum].	30.23	612	365	20	2	574	3	591	3e-51	198
tr:E1YZG1_9PORP	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:EFK61037.1}; Flags: Fragment;	33.25	406	235	11	1	385	20	410	3e-51	194
rs:WP_034530646	DNA topoisomerase I, partial [Parabacteroides sp. 20_3].	33.25	406	235	11	1	385	1	391	4e-51	193
tr:K1URV5_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC74216.1}; Flags: Fragment;	34.36	326	191	7	3	321	4	313	4e-51	191
rs:WP_016103582	DNA topoisomerase III [Bacillus cereus].	27.43	711	449	22	3	673	5	688	4e-51	201
rs:WP_031915414	DNA topoisomerase III, partial [Staphylococcus aureus].	33.02	421	262	10	157	567	17	427	4e-51	194
rs:WP_044155318	DNA topoisomerase I, partial [Bacteroides intestinalis].	27.89	563	371	14	130	677	24	566	4e-51	197
rs:WP_035262180	hypothetical protein, partial [Desulfonatronum lacustre].	26.88	640	381	21	3	577	4	621	4e-51	198
rs:WP_031794362	DNA topoisomerase III, partial [Staphylococcus aureus].	34.09	399	237	13	3	388	4	389	4e-51	193
rs:WP_037526447	DNA topoisomerase I, partial [Sphingobacterium sp. IITKGP-BTPF85].	32.77	415	246	13	1	394	1	403	4e-51	194
rs:WP_024396453	DNA topoisomerase [Streptococcus suis].	29.08	595	361	18	3	573	4	561	4e-51	197
tr:E4IKL2_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.06	613	380	17	109	675	10	607	4e-51	198
rs:WP_033642401	DNA topoisomerase, partial [Enterococcus faecium].	28.06	613	380	17	109	675	1	598	5e-51	197
rs:WP_023934205	DNA topoisomerase [Photobacterium leiognathi].	26.45	688	440	25	1	640	1	670	5e-51	199
tr:E4ICB9_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.06	613	380	17	109	675	10	607	5e-51	198
rs:WP_043031848	DNA topoisomerase [Clostridium botulinum].	29.90	612	367	20	2	574	3	591	5e-51	198
rs:WP_033645481	DNA topoisomerase, partial [Enterococcus faecium].	28.06	613	380	17	109	675	1	598	5e-51	197
tr:C2FZU9_9SPHI	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEI91545.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EEI91545.1};	33.74	412	232	14	1	387	1	396	5e-51	194
rs:WP_034347888	DNA topoisomerase III, partial [Helicobacter trogontum].	28.37	624	378	15	1	574	1	605	5e-51	198
rs:WP_034020521	DNA topoisomerase III [Pseudomonas aeruginosa].	25.89	730	472	20	1	680	1	711	5e-51	199
rs:WP_036856688	DNA topoisomerase I, partial [Prevotella amnii].	31.84	424	259	11	4	414	5	411	5e-51	194
rs:WP_040367708	DNA topoisomerase, partial [Enterococcus italicus].	28.19	596	385	14	117	675	4	593	5e-51	197
rs:WP_047209919	DNA topoisomerase [Streptococcus agalactiae].	29.24	595	360	18	3	573	4	561	6e-51	197
rs:WP_000520756	DNA topoisomerase I [Bacillus cereus].	27.86	646	414	19	41	655	46	670	6e-51	200
rs:WP_033559033	DNA topoisomerase III [Escherichia coli].	25.65	768	463	24	1	673	1	755	6e-51	199
rs:WP_008790355	MULTISPECIES: hypothetical protein [Coprobacillus].	27.60	732	451	24	2	682	8	711	6e-51	199
rs:WP_033125583	DNA topoisomerase III [Eubacterium sp. ER2].	26.39	667	394	20	3	579	5	664	6e-51	199
tr:R8CKW2_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.83	690	437	21	3	655	5	670	6e-51	200
rs:WP_000520755	DNA topoisomerase I [Bacillus thuringiensis].	27.71	664	428	19	41	673	46	688	6e-51	200
rs:WP_025367771	DNA topoisomerase III [Klebsiella pneumoniae].	26.66	769	457	26	1	673	1	758	6e-51	199
tr:V2Y4D4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.62	665	399	20	3	590	5	657	7e-51	198
gpu:CP006907_185	DNA topoisomerase family protein [Clostridium botulinum CDC_297]	30.07	612	366	20	2	574	3	591	7e-51	197
rs:WP_003360737	DNA topoisomerase III [Clostridium botulinum].	30.07	612	366	20	2	574	3	591	7e-51	197
tr:F3FN33_PSESX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.21	553	353	14	109	629	1	541	7e-51	196
tr:C0AQN2_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.46	415	231	15	1	384	1	405	7e-51	193
rs:WP_000520754	DNA topoisomerase I [Bacillus cereus].	27.49	662	432	20	41	673	46	688	7e-51	199
rs:WP_033995596	DNA topoisomerase III [Pseudomonas aeruginosa].	26.06	733	467	20	1	680	1	711	8e-51	199
tr:D6CZ79_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.70	607	405	16	85	680	37	608	8e-51	197
rs:WP_027722150	DNA topoisomerase I [Desulfovibrio zosterae].	25.42	716	464	20	1	668	1	694	8e-51	199
rs:WP_031861022	DNA topoisomerase III, partial [Staphylococcus aureus].	30.89	492	316	11	40	516	13	495	8e-51	195
rs:WP_022295803	DNA topoisomerase [Firmicutes bacterium CAG:272].	26.86	726	450	27	1	676	1	695	8e-51	198
rs:WP_000520737	DNA topoisomerase I [Bacillus thuringiensis].	27.43	711	449	22	3	673	5	688	8e-51	199
tr:B3CB28_9BACE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EDV04280.1};	27.89	563	371	14	130	677	59	601	8e-51	197
rs:WP_030034759	DNA topoisomerase III [Clostridium botulinum].	29.90	612	367	20	2	574	3	591	8e-51	197
rs:WP_002342368	DNA topoisomerase III [Enterococcus faecium].	30.51	495	318	9	103	581	3	487	8e-51	195
rs:WP_012721099	DNA topoisomerase III [Clostridium botulinum].	30.07	612	366	20	2	574	3	591	8e-51	197
rs:WP_016306102	hypothetical protein [Lachnospiraceae bacterium A2].	25.44	688	397	19	3	579	5	687	9e-51	198
tr:I7B516_PSEPT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.14	453	279	12	1	425	1	439	9e-51	194
rs:WP_011108421	DNA topoisomerase I [Bacteroides thetaiotaomicron].	26.55	614	392	17	1	589	1	580	9e-51	196
rs:WP_006816384	DNA topoisomerase III [Providencia rustigianii].	27.22	698	436	26	1	646	1	678	9e-51	199
rs:WP_021413190	DNA topoisomerase III, partial [Peptoclostridium difficile].	26.47	714	418	26	1	638	1	683	9e-51	198
rs:WP_010297015	DNA topoisomerase III [Clostridium senegalense].	29.87	616	357	23	3	571	4	591	1e-50	197
tr:A0A0E1SW33_HAEIF	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EDK12149.1};	29.71	478	289	15	1	439	1	470	1e-50	195
rs:WP_000520741	DNA topoisomerase I [Bacillus cereus].	27.26	708	454	21	3	673	5	688	1e-50	199
rs:WP_026883648	DNA topoisomerase III [Clostridium akagii].	27.90	681	404	24	1	633	1	642	1e-50	197
rs:WP_009662480	DNA topoisomerase III [Lachnoanaerobaculum sp. ICM7].	27.43	638	394	17	2	578	3	632	1e-50	197
rs:WP_038313770	DNA topoisomerase III [Kingella kingae].	27.31	670	406	22	68	682	1	644	1e-50	197
rs:WP_003486473	DNA topoisomerase III [Clostridium sporogenes].	29.90	612	367	20	2	574	3	591	1e-50	197
rs:WP_008026503	DNA topoisomerase III [Bacteroides xylanisolvens].	26.71	614	391	17	1	589	1	580	1e-50	196
tr:C3FBJ1_BACTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.26	664	431	19	41	673	46	688	1e-50	199
tr:G1VGY7_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGW46163.1};	33.25	424	253	12	4	414	5	411	1e-50	193
rs:WP_022379889	DNA topoisomerase III [Ruminococcus sp. CAG:9].	25.48	726	430	20	3	622	5	725	1e-50	198
tr:A0A0A8W8B0_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.65	727	439	22	2	682	3	688	1e-50	197
rs:WP_000520752	DNA topoisomerase I [Bacillus thuringiensis].	27.06	654	445	17	41	673	46	688	1e-50	199
rs:WP_025147939	DNA topoisomerase I [Bacillus sp. H1a].	27.29	711	450	22	3	673	5	688	1e-50	199
rs:WP_033728948	DNA topoisomerase I [Bacillus weihenstephanensis].	27.26	708	454	21	3	673	5	688	1e-50	199
rs:WP_016084166	DNA topoisomerase III [Bacillus cereus].	27.09	683	442	21	32	681	37	696	1e-50	199
tr:A0A0B0HYH2_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	35.89	326	193	8	3	321	4	320	1e-50	191
rs:WP_032716084	DNA topoisomerase III [Enterobacter aerogenes].	25.65	768	463	24	1	673	1	755	1e-50	198
rs:WP_008778023	DNA topoisomerase III [Parabacteroides sp. 20_3].	26.75	613	402	17	1	594	1	585	1e-50	196
rs:WP_008707501	DNA topoisomerase III [Ruminococcus sp. 5_1_39BFAA].	25.48	726	430	20	3	622	5	725	2e-50	197
rs:WP_022011364	DNA topoisomerase III [Bacteroides fragilis CAG:558].	29.94	521	329	17	171	676	1	500	2e-50	194
rs:WP_045221390	hypothetical protein, partial [Desulfonatronum thioautotrophicum].	26.57	621	374	18	3	560	4	605	2e-50	196
tr:D8L9Y3_CAMFE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:CBH51817.1};	27.12	697	429	22	2	640	3	678	2e-50	197
tr:G4BEE6_AGGAP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.57	436	244	15	1	399	1	423	2e-50	194
rs:WP_033951578	DNA topoisomerase III [Pseudomonas aeruginosa].	25.92	733	468	20	1	680	1	711	2e-50	197
rs:WP_045665981	hypothetical protein, partial [Pseudomonas sp. BRH_c35].	26.06	614	408	16	3	580	4	607	2e-50	196
rs:WP_031840280	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	29.86	442	282	7	166	581	2	441	2e-50	193
rs:WP_002204216	DNA topoisomerase I [Bacillus cereus].	27.40	708	453	21	3	673	5	688	2e-50	198
rs:WP_034849209	DNA topoisomerase, partial [Clostridium hydrogeniformans].	29.15	614	366	21	3	571	4	593	2e-50	196
rs:WP_042061035	DNA topoisomerase III [Escherichia coli].	26.37	766	463	23	1	673	1	758	3e-50	197
rs:WP_016362159	DNA topoisomerase III [Bacillus cereus].	27.29	711	450	23	3	673	5	688	3e-50	198
rs:WP_032542490	DNA topoisomerase I [Bacteroides fragilis].	25.66	608	404	17	85	680	37	608	3e-50	196
rs:WP_019389429	hypothetical protein [Kingella kingae].	27.16	670	407	22	68	682	1	644	3e-50	196
rs:WP_025370374	hypothetical protein [Campylobacter fetus].	28.42	665	414	21	2	620	3	651	3e-50	197
rs:WP_016513361	DNA topoisomerase III [Bacillus cereus].	27.71	711	447	22	3	673	5	688	3e-50	198
tr:A0A084ITG9_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.26	708	454	20	3	673	5	688	3e-50	198
rs:WP_011367300	DNA topoisomerase III [Desulfovibrio alaskensis].	29.38	497	318	13	209	681	276	763	3e-50	197
rs:WP_011367300	DNA topoisomerase III [Desulfovibrio alaskensis].	32.89	228	138	6	3	224	5	223	2e-29	135
rs:WP_013389292	DNA topoisomerase III [Ilyobacter polytropus].	28.97	649	385	23	1	618	1	604	3e-50	196
rs:WP_003491116	DNA topoisomerase III [Clostridium sporogenes].	29.58	612	369	20	2	574	3	591	3e-50	196
rs:WP_002094784	DNA topoisomerase I [Bacillus cereus].	27.26	708	454	21	3	673	5	688	3e-50	197
tr:J9CNG0_9ZZZZ	SubName: Full=DNA topoisomerase TopB {ECO:0000313|EMBL:EJX01646.1};	27.22	632	372	19	1	593	10	592	3e-50	195
rs:WP_005679476	DNA topoisomerase III [Bacteroides caccae].	26.55	614	392	17	1	589	1	580	3e-50	195
tr:A0A0C7LRN9_CLOSO	SubName: Full=TopA_2 protein {ECO:0000313|EMBL:CEP45728.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEP45728.1};	28.16	728	434	23	2	682	3	688	3e-50	196
rs:WP_035040382	hypothetical protein, partial [Catonella morbi].	26.87	655	385	21	3	578	5	644	3e-50	196
rs:WP_016107050	DNA topoisomerase III [Bacillus cereus].	27.12	708	455	19	3	673	5	688	3e-50	198
rs:WP_027181485	DNA topoisomerase III [Desulfovibrio alaskensis].	29.38	497	318	13	209	681	276	763	3e-50	197
rs:WP_027181485	DNA topoisomerase III [Desulfovibrio alaskensis].	32.89	228	138	6	3	224	5	223	1e-29	135
rs:WP_025577250	DNA topoisomerase III [Blautia wexlerae].	25.76	726	428	21	3	622	5	725	4e-50	196
rs:WP_010728928	DNA topoisomerase III [Enterococcus faecium].	30.51	495	318	9	103	581	3	487	4e-50	193
rs:WP_044269192	DNA topoisomerase I [Candidatus Bacteroides timonensis].	26.59	613	403	17	1	594	1	585	4e-50	195
rs:WP_044931597	hypothetical protein, partial [Butyrivibrio sp. AC2005].	27.30	685	424	22	3	625	4	676	4e-50	196
rs:WP_004323216	DNA topoisomerase III [Bacteroides ovatus].	26.71	614	391	17	1	589	1	580	4e-50	195
rs:WP_000520740	DNA topoisomerase I [Bacillus cereus].	27.41	704	458	20	3	673	5	688	4e-50	197
rs:WP_040209776	DNA topoisomerase III [Klebsiella pneumoniae].	26.75	770	455	29	1	673	1	758	4e-50	197
rs:WP_011246962	DNA topoisomerase [Bacillus clausii].	27.12	719	460	24	1	677	1	697	5e-50	196
rs:WP_004199098	MULTISPECIES: DNA topoisomerase III [Bacteria].	26.75	770	455	29	1	673	1	758	5e-50	196
rs:WP_004288696	DNA topoisomerase III [Bacteroides eggerthii].	26.77	609	399	17	1	590	1	581	5e-50	194
rs:WP_000280355	DNA topoisomerase III [Bacillus thuringiensis].	26.13	727	458	22	1	661	1	714	5e-50	196
rs:WP_044134826	DNA topoisomerase I, partial [Bacteroides fragilis].	26.63	597	383	16	1	572	1	567	5e-50	194
rs:WP_033607002	hypothetical protein, partial [Enterococcus faecium].	28.60	584	384	15	130	686	5	582	5e-50	194
rs:WP_032825815	DNA topoisomerase III, partial [Haemophilus haemolyticus].	31.47	429	245	15	1	389	1	420	5e-50	191
tr:J7YG53_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.12	708	455	21	3	673	5	688	5e-50	197
rs:WP_005858550	DNA topoisomerase III [Parabacteroides distasonis].	26.59	613	403	17	1	594	1	585	5e-50	194
rs:WP_019716635	DNA topoisomerase III, partial [Pseudomonas syringae].	27.36	625	392	19	1	578	1	610	6e-50	195
rs:WP_025232898	DNA topoisomerase III [Clostridium sp. ASBs410].	24.85	680	400	16	3	578	5	677	6e-50	196
rs:WP_038328472	DNA topoisomerase III [Kingella kingae].	27.16	670	407	22	68	682	1	644	6e-50	195
rs:WP_029392519	DNA topoisomerase III, partial [Escherichia coli].	28.97	649	398	18	84	680	7	644	6e-50	195
rs:WP_021583868	DNA topoisomerase, partial [Prevotella pleuritidis].	33.88	425	249	12	4	414	5	411	7e-50	191
rs:WP_037404202	MULTISPECIES: DNA topoisomerase III [Serratia].	26.10	774	466	27	1	678	1	764	7e-50	196
rs:WP_017684961	DNA topoisomerase III [Pseudomonas syringae].	27.36	625	392	19	1	578	1	610	7e-50	195
rs:WP_017108524	hypothetical protein [Vibrio tasmaniensis].	27.67	694	426	27	1	640	1	672	7e-50	196
rs:WP_016359326	DNA topoisomerase III [Pseudomonas fluorescens].	25.51	737	474	23	1	684	1	715	7e-50	196
rs:WP_034073868	DNA topoisomerase III [Pseudomonas aeruginosa].	25.48	730	475	20	1	680	1	711	8e-50	196
tr:F3F3R3_PSEA0	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	29.72	562	344	14	1	520	1	553	9e-50	193
rs:WP_045348202	DNA topoisomerase III [Enterobacter cloacae].	25.91	768	464	25	1	673	1	758	9e-50	196
tr:A0A0A1SBJ6_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.02	728	435	23	2	682	3	688	9e-50	195
rs:WP_007832816	DNA topoisomerase III [Bacteroides dorei].	26.60	609	400	17	1	590	1	581	9e-50	194
rs:WP_044124831	DNA topoisomerase I, partial [Prevotella loescheii].	32.31	424	257	11	4	414	5	411	9e-50	190
rs:WP_016128043	DNA topoisomerase III [Bacillus cereus].	27.40	708	453	21	3	673	5	688	1e-49	196
rs:WP_039680621	DNA topoisomerase [Terrisporobacter othiniensis].	26.32	741	465	25	1	680	1	721	1e-49	195
rs:WP_021997716	DNA topoisomerase [Ruminococcus sp. CAG:724].	27.30	729	451	25	1	676	1	703	1e-49	195
rs:WP_046427909	hypothetical protein [Burkholderia vietnamiensis].	25.94	667	440	20	2	629	5	656	1e-49	194
rs:WP_000520738	DNA topoisomerase I [Bacillus cereus].	27.29	711	450	22	3	673	5	688	1e-49	196
rs:WP_015757378	DNA topoisomerase III [Desulfotomaculum acetoxidans].	30.28	459	300	10	235	676	290	745	1e-49	195
rs:WP_015757378	DNA topoisomerase III [Desulfotomaculum acetoxidans].	41.05	229	117	7	2	223	3	220	9e-33	145
rs:WP_022302396	DNA topoisomerase III [Bacteroides faecis CAG:32].	26.50	615	399	15	1	593	1	584	1e-49	193
rs:WP_033553424	DNA topoisomerase III [Escherichia coli].	27.99	711	445	21	1	664	1	691	1e-49	195
rs:WP_005802573	DNA topoisomerase III [Bacteroides fragilis].	26.60	609	400	17	1	590	1	581	1e-49	193
rs:WP_047254498	DNA topoisomerase [Enterococcus cecorum].	28.37	726	432	29	3	680	4	689	1e-49	195
rs:WP_002187829	DNA topoisomerase I [Bacillus cereus].	27.12	708	455	21	3	673	5	688	1e-49	196
rs:WP_017097009	hypothetical protein [Vibrio tasmaniensis].	27.67	694	426	27	1	640	1	672	1e-49	195
rs:WP_042825262	hypothetical protein [Xanthomonas axonopodis].	25.60	668	389	20	2	583	5	650	1e-49	195
rs:WP_002339858	DNA topoisomerase III [Enterococcus faecium].	28.93	553	353	11	103	629	3	541	1e-49	192
rs:WP_025790155	DNA topoisomerase I, partial [Prevotella loescheii].	32.31	424	257	11	4	414	5	411	1e-49	189
rs:WP_044322475	DNA topoisomerase III, partial [Pseudomonas amygdali].	27.75	627	387	21	1	578	1	610	1e-49	194
rs:WP_001235774	hypothetical protein, partial [Escherichia coli].	27.50	691	432	26	1	640	1	673	1e-49	194
rs:WP_037029964	DNA topoisomerase [Psychrilyobacter atlanticus].	28.82	642	393	22	1	618	1	602	2e-49	194
rs:WP_034439060	DNA topoisomerase [Candidatus Clostridium anorexicamassiliense].	29.20	613	366	22	3	572	4	591	2e-49	193
rs:WP_009009747	DNA topoisomerase [Coprobacillus sp. D7].	27.67	730	452	31	1	687	1	697	2e-49	195
rs:WP_026649430	DNA topoisomerase III [Blautia wexlerae].	25.48	726	430	20	3	622	5	725	2e-49	194
rs:WP_026747454	DNA topoisomerase [Leptotrichia trevisanii].	29.08	705	424	26	2	673	3	664	2e-49	194
rs:WP_033027589	DNA topoisomerase III, partial [Geobacillus sp. MAS1].	30.58	412	263	11	1	392	1	409	2e-49	189
rs:WP_040120508	DNA topoisomerase III [Klebsiella pneumoniae].	26.62	770	456	29	1	673	1	758	2e-49	194
rs:WP_044653275	DNA topoisomerase I [Bacteroides acidifaciens].	26.55	614	392	17	1	589	1	580	2e-49	192
rs:WP_015256841	DNA topoisomerase III TopB [Klebsiella pneumoniae].	26.58	696	444	20	1	646	1	679	2e-49	194
rs:WP_015061875	DNA topoisomerase III [Pseudomonas syringae].	25.71	735	473	23	1	684	1	713	2e-49	194
rs:WP_027105433	DNA topoisomerase III [Lachnospiraceae bacterium V9D3004].	26.80	709	381	21	3	580	5	706	2e-49	194
rs:WP_044167350	DNA topoisomerase III, partial [Staphylococcus aureus].	34.45	389	229	13	3	378	4	379	2e-49	187
rs:WP_032881471	DNA topoisomerase III [Pseudomonas sp. BRG-100].	25.62	730	476	20	1	684	1	709	2e-49	194
tr:V6V9G4_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.36	415	260	11	1	392	1	409	2e-49	189
rs:WP_024346744	DNA topoisomerase III [[Clostridium] methoxybenzovorans].	25.81	682	392	20	3	578	5	678	2e-49	194
rs:WP_045282368	DNA topoisomerase III [Enterobacter sp. 44593].	26.72	696	443	20	1	646	1	679	3e-49	194
rs:WP_023662392	DNA topoisomerase III, partial [Pseudomonas taiwanensis].	28.26	453	283	11	1	425	1	439	3e-49	189
rs:WP_000280354	hypothetical protein [Bacillus cereus].	26.20	729	455	22	1	661	1	714	3e-49	194
rs:WP_032508493	DNA topoisomerase III, partial [Peptoclostridium difficile].	28.71	613	373	23	1	580	1	582	3e-49	192
tr:A7LUK2_BACO1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.41	602	378	16	1	572	1	567	3e-49	192
tr:F3PYL3_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.06	632	373	19	1	593	10	592	3e-49	192
tr:A0A0A8W477_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.88	728	436	23	2	682	3	688	3e-49	194
rs:WP_038281769	DNA topoisomerase III [[Clostridium] celerecrescens].	24.74	679	401	16	3	578	5	676	3e-49	194
rs:WP_016090829	DNA topoisomerase III [Bacillus cereus].	27.43	711	449	22	3	673	5	688	3e-49	195
rs:WP_002169636	DNA topoisomerase I [Bacillus cereus].	27.27	693	437	20	3	655	5	670	3e-49	195
rs:WP_039969953	DNA topoisomerase I [Bacteroides fluxus].	27.06	632	373	19	1	593	1	583	3e-49	192
rs:WP_004323380	MULTISPECIES: DNA topoisomerase III [Bacteroides].	26.25	602	379	16	1	572	1	567	3e-49	192
tr:F9GLD9_HAEHA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.47	429	245	15	1	389	1	420	3e-49	189
rs:WP_011345748	DNA topoisomerase TraE [Xanthomonas euvesicatoria].	25.08	662	400	20	2	583	5	650	3e-49	194
tr:K1UE89_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC76530.1}; Flags: Fragment;	33.55	310	191	6	1	307	14	311	3e-49	185
rs:WP_033716935	DNA topoisomerase III, partial [Bacillus cereus].	33.48	460	269	14	193	627	10	457	4e-49	191
rs:WP_008026309	DNA topoisomerase III [Bacteroides xylanisolvens].	26.41	602	378	16	1	572	1	567	4e-49	192
rs:WP_044715191	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	25.64	776	471	22	1	681	1	765	4e-49	194
rs:WP_002191962	DNA topoisomerase I [Bacillus cereus].	27.33	688	443	23	3	655	5	670	4e-49	194
rs:WP_002166603	DNA topoisomerase I [Bacillus cereus].	27.29	700	464	21	3	673	5	688	5e-49	194
rs:WP_005552553	DNA topoisomerase 3 [Paenibacillus alvei].	25.77	718	470	17	1	666	1	707	5e-49	195
tr:J8ACM7_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.48	460	269	14	193	627	24	471	5e-49	191
rs:WP_044124897	DNA topoisomerase I, partial [Prevotella loescheii].	31.15	427	264	11	1	414	2	411	5e-49	188
rs:WP_043039283	DNA topoisomerase [Streptococcus equi].	29.51	593	361	18	3	573	4	561	5e-49	191
rs:WP_004095637	DNA topoisomerase III, partial [Acetonema longum].	26.47	665	419	23	1	623	1	637	6e-49	192
rs:WP_001549937	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	26.01	769	462	25	1	673	1	758	6e-49	193
rs:WP_013330742	MULTISPECIES: topoisomerase IA [Enterococcus].	28.20	610	373	19	117	679	6	597	6e-49	191
tr:R3FTE9_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.45	566	348	16	154	675	1	553	6e-49	191
rs:WP_002346508	DNA topoisomerase III [Streptococcus suis].	28.45	566	348	16	154	675	1	553	7e-49	191
rs:WP_009300879	DNA topoisomerase [Coprobacillus sp. 3_3_56FAA].	27.50	731	452	31	1	687	1	697	7e-49	193
rs:WP_025790182	DNA topoisomerase I, partial [Prevotella loescheii].	31.15	427	264	11	1	414	2	411	7e-49	187
tr:Q19V32_HAEIF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.68	423	240	15	1	383	1	414	7e-49	187
rs:WP_007560996	DNA topoisomerase III [Bacteroides plebeius].	26.18	615	401	15	1	593	1	584	7e-49	191
rs:WP_003464928	DNA topoisomerase III [Clostridium perfringens].	28.65	719	445	22	2	680	3	693	8e-49	192
rs:WP_002151036	DNA topoisomerase I [Bacillus cereus].	27.12	708	455	21	3	673	5	688	8e-49	194
tr:A0A0A8VYF7_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.15	714	421	24	2	667	3	672	8e-49	192
rs:WP_036745280	hypothetical protein, partial [Peptoclostridium difficile].	25.70	642	436	14	1	615	1	628	8e-49	191
rs:WP_029659095	DNA topoisomerase, partial [Enterococcus faecalis].	28.45	566	348	16	154	675	8	560	8e-49	191
rs:WP_040215770	DNA topoisomerase III, partial [Klebsiella pneumoniae].	27.35	691	433	26	1	640	1	673	9e-49	192
tr:A0A066ZGK8_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.45	566	348	16	154	675	15	567	9e-49	191
rs:WP_031942367	DNA topoisomerase III [Escherichia coli].	28.82	628	400	15	84	673	10	628	9e-49	191
rs:WP_044677372	DNA topoisomerase, partial [Streptococcus suis].	30.53	524	309	16	3	490	4	508	9e-49	189
rs:WP_022426265	DNA topoisomerase [Ruminococcus sp. CAG:90].	25.67	635	398	20	28	594	14	642	9e-49	192
rs:WP_044423469	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	27.43	525	346	13	1	498	1	517	1e-48	189
tr:B1BLL7_CLOPF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.29	714	454	21	2	680	3	693	1e-48	192
rs:WP_032834767	DNA topoisomerase [Fusobacterium sp. OBRC1].	28.15	714	460	22	1	680	1	695	1e-48	192
tr:A0A0D0S6Q2_9FIRM	SubName: Full=TWA4_scaffold00001, whole genome shotgun sequence {ECO:0000313|EMBL:KIR01912.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIR01912.1};	28.01	607	374	18	31	580	5	605	1e-48	191
rs:WP_015059067	DNA topoisomerase III [Escherichia coli].	25.75	769	464	24	1	673	1	758	1e-48	192
rs:WP_033798032	DNA topoisomerase III, partial [Bacillus mycoides].	33.84	458	270	13	193	627	10	457	1e-48	189
tr:K1TWC1_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC77422.1}; Flags: Fragment;	33.54	328	195	7	1	321	1	312	1e-48	184
rs:WP_031922918	DNA topoisomerase III, partial [Staphylococcus aureus].	33.93	389	231	13	3	378	4	379	1e-48	186
rs:WP_033426509	hypothetical protein, partial [Salinicoccus albus].	29.08	595	353	21	130	680	6	575	1e-48	190
rs:WP_021542872	hypothetical protein [Escherichia coli].	26.01	769	462	24	1	673	1	758	1e-48	192
rs:WP_000520739	DNA topoisomerase I [Bacillus cereus].	27.41	704	458	23	3	673	5	688	1e-48	193
tr:A0A0D5PRC1_XANCI	SubName: Full=DNA topoisomerase III, bacteria and conjugative plasmid {ECO:0000313|EMBL:AJY91182.1};	27.37	548	353	16	130	639	18	558	1e-48	190
rs:WP_029655964	DNA topoisomerase, partial [Enterococcus faecalis].	28.45	566	348	16	154	675	8	560	2e-48	189
tr:A0A011QH80_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.53	603	358	22	2	553	4	578	2e-48	190
rs:WP_000419478	hypothetical protein, partial [Salmonella enterica].	32.15	367	235	6	256	615	56	415	2e-48	187
rs:WP_029658328	DNA topoisomerase, partial [Enterococcus faecalis].	28.45	566	348	16	154	675	8	560	2e-48	189
rs:WP_022233276	DNA topoisomerase III [Bacteroides sp. CAG:443].	26.09	617	399	15	1	593	1	584	2e-48	190
tr:J7HU65_BACTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.77	623	411	16	32	625	37	649	2e-48	191
rs:WP_032585425	DNA topoisomerase I [Bacteroides fragilis].	26.09	617	399	16	1	593	1	584	2e-48	190
gpu:CP011588_29	DNA topoisomerase III [Enterobacter asburiae]	26.58	696	444	20	1	646	1	679	2e-48	191
rs:WP_025700989	hypothetical protein, partial [Paenibacillus forsythiae].	35.71	322	191	9	3	317	4	316	2e-48	183
rs:WP_024295612	MULTISPECIES: DNA topoisomerase III [Lachnoclostridium].	25.66	682	393	20	3	578	5	678	2e-48	191
rs:WP_045325285	DNA topoisomerase III [Enterobacter cloacae].	26.14	769	461	25	1	673	1	758	2e-48	191
rs:WP_005682871	DNA topoisomerase III [Bacteroides caccae].	25.96	601	398	16	1	582	1	573	3e-48	189
tr:C3DWF6_BACTS	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEM37751.1};	26.85	648	429	19	65	678	19	655	3e-48	191
rs:WP_029658570	DNA topoisomerase, partial [Enterococcus faecalis].	28.45	566	348	16	154	675	8	560	3e-48	189
rs:WP_017643219	DNA topoisomerase [Streptococcus agalactiae].	28.74	595	367	19	3	574	4	564	3e-48	189
rs:WP_004326356	MULTISPECIES: DNA topoisomerase III [Bacteroides].	26.26	617	398	16	1	593	1	584	3e-48	189
rs:WP_027365964	hypothetical protein, partial [Desulfotomaculum alcoholivorax].	35.19	324	184	9	3	312	6	317	3e-48	183
rs:WP_019036494	hypothetical protein, partial [Prevotella amnii].	31.40	449	236	16	4	414	5	419	3e-48	186
rs:WP_041584091	DNA topoisomerase I [Bacteroides salanitronis].	25.77	617	405	14	1	595	1	586	3e-48	189
rs:WP_021444245	hypothetical protein, partial [Pseudomonas sp. EGD-AK9].	29.78	450	292	9	188	614	7	455	3e-48	187
rs:WP_017648013	DNA topoisomerase [Streptococcus agalactiae].	28.45	594	370	18	3	574	4	564	4e-48	189
rs:WP_005841655	DNA topoisomerase, partial [Bacteroides vulgatus].	29.17	528	336	17	173	684	1	506	4e-48	188
rs:WP_005776835	MULTISPECIES: DNA topoisomerase III [Bacteroides].	26.18	615	401	15	1	593	1	584	4e-48	189
rs:WP_032494175	topoisomerase I, partial [Enterococcus faecium].	28.08	577	362	17	117	655	5	566	4e-48	189
tr:F0R4F1_BACSH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.73	618	404	15	1	595	23	608	4e-48	189
rs:WP_044322571	DNA topoisomerase III, partial [Pseudomonas amygdali].	27.59	627	388	19	1	578	1	610	4e-48	189
rs:WP_025191329	DNA topoisomerase, partial [Enterococcus faecalis].	28.72	585	349	20	117	654	1	564	4e-48	189
rs:WP_041488010	DNA topoisomerase I, partial [Bacillus thuringiensis].	28.09	566	383	13	32	581	37	594	4e-48	189
rs:WP_010944885	DNA topoisomerase III [Haemophilus ducreyi].	29.24	472	294	11	1	444	1	460	4e-48	187
rs:WP_025789617	DNA topoisomerase III [Vibrio parahaemolyticus].	25.69	728	459	23	1	671	1	703	5e-48	190
rs:WP_046720418	DNA topoisomerase III [Pseudomonas syringae].	25.31	731	480	20	1	684	1	712	5e-48	190
rs:WP_031471795	DNA topoisomerase III, partial [[Clostridium] aminophilum].	25.92	679	391	22	3	580	5	672	5e-48	190
tr:A0A091C1Y9_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.28	393	264	7	41	425	3	393	5e-48	185
rs:WP_047345337	DNA topoisomerase III [Enterobacter sp. GN03164].	26.26	735	479	21	1	687	1	720	6e-48	190
rs:WP_042060806	DNA topoisomerase III [Escherichia coli].	25.85	735	482	22	1	687	1	720	6e-48	190
rs:WP_002244206	DNA topoisomerase [Neisseria meningitidis].	24.62	727	470	22	3	683	5	699	6e-48	190
rs:WP_000280353	DNA topoisomerase III [Bacillus cereus].	26.13	727	458	23	1	661	1	714	7e-48	190
tr:R3JUZ9_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.77	570	340	19	130	654	16	564	7e-48	188
rs:WP_036857354	DNA topoisomerase I, partial [Prevotella amnii].	30.73	423	265	9	4	414	5	411	7e-48	186
tr:E6LIS5_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.19	557	361	12	154	675	1	553	8e-48	187
rs:WP_000876323	DNA topoisomerase [Streptococcus agalactiae].	29.08	595	365	18	3	574	4	564	8e-48	188
rs:WP_006882087	MULTISPECIES: topoisomerase [Enterobacteriaceae].	26.80	735	475	23	1	687	1	720	8e-48	189
rs:WP_008645712	hypothetical protein, partial [Bacteroides sp. 1_1_30].	31.64	414	249	13	1	394	1	400	8e-48	186
rs:WP_010700012	DNA topoisomerase [Acinetobacter radioresistens].	25.13	756	458	27	1	671	1	733	8e-48	191
rs:WP_022282048	DNA topoisomerase [Clostridium sp. CAG:448].	25.31	719	473	21	1	673	1	701	9e-48	189
rs:WP_000604073	hypothetical protein [Escherichia coli].	25.85	735	482	22	1	687	1	720	9e-48	189
rs:WP_041167430	DNA topoisomerase [Pseudomonas putida].	26.37	622	372	17	68	615	1	610	9e-48	188
rs:WP_024549111	MULTISPECIES: DNA topoisomerase III [Cronobacter].	26.80	735	475	23	1	687	1	720	9e-48	189
rs:WP_044278347	DNA topoisomerase III, partial [Campylobacter jejuni].	29.50	522	333	14	1	497	1	512	1e-47	186
tr:E7S6H7_STRAG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.08	595	365	18	3	574	11	571	1e-47	187
rs:WP_003482634	DNA topoisomerase III [Clostridium perfringens].	28.01	714	456	21	2	680	3	693	1e-47	189
rs:WP_004294133	DNA topoisomerase III [Bacteroides eggerthii].	25.69	615	404	14	1	593	1	584	1e-47	187
rs:WP_008778027	DNA topoisomerase III, partial [Parabacteroides sp. 20_3].	35.03	334	191	8	1	318	1	324	1e-47	182
rs:WP_021439520	DNA topoisomerase [Neisseria meningitidis].	24.62	727	470	22	3	683	5	699	1e-47	189
rs:WP_033693711	DNA topoisomerase III [Bacillus cereus].	26.13	727	458	23	1	661	1	714	1e-47	189
tr:S4W680_STRAG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.57	595	368	19	3	574	4	564	1e-47	187
rs:WP_033690675	DNA topoisomerase, partial [Pseudomonas sp. TJI-51].	26.48	623	370	18	68	615	1	610	1e-47	188
rs:WP_040146911	DNA topoisomerase III, partial [Xanthomonas citri].	27.52	447	294	11	1	425	1	439	1e-47	185
rs:WP_025190821	DNA topoisomerase, partial [Enterococcus faecalis].	28.55	585	350	20	117	654	1	564	1e-47	187
rs:WP_039476110	DNA topoisomerase III [Pectobacterium carotovorum].	26.17	707	436	23	1	646	1	682	1e-47	189
rs:WP_017768605	DNA topoisomerase [Streptococcus agalactiae].	28.24	595	370	19	3	574	4	564	1e-47	187
rs:WP_000604074	DNA topoisomerase III [Salmonella enterica].	26.12	735	480	21	1	687	1	720	1e-47	189
rs:WP_039064406	DNA topoisomerase III, partial [Shigella boydii].	28.84	638	404	17	64	664	1	625	1e-47	188
tr:E1KTZ0_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFL45038.1};	31.21	423	263	10	4	414	5	411	1e-47	186
rs:WP_021127600	DNA topoisomerase III [[Clostridium] sordellii].	28.28	725	437	25	2	682	3	688	1e-47	189
rs:WP_044563142	DNA topoisomerase [Streptococcus macedonicus].	28.91	595	366	18	3	574	15	575	1e-47	187
tr:F0E713_PSEDT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.37	622	372	17	68	615	1	610	1e-47	188
tr:H2A926_STRMD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.91	595	366	18	3	574	4	564	1e-47	187
rs:WP_043459152	hypothetical protein, partial [Azohydromonas australica].	26.46	548	355	17	168	675	47	586	1e-47	187
rs:WP_001773473	DNA topoisomerase III [Escherichia coli].	25.81	775	467	26	1	678	1	764	2e-47	189
rs:WP_001689137	DNA topoisomerase, partial [Escherichia coli].	30.20	563	346	14	150	673	31	585	2e-47	187
gp:CP001927_17	DNA topoisomerase III [Escherichia coli Xuzhou21]	25.85	735	482	22	1	687	49	768	2e-47	189
tr:G4B181_AGGAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.93	443	248	16	1	399	1	429	2e-47	186
rs:WP_041787144	DNA topoisomerase [Streptococcus constellatus].	28.07	595	370	17	3	574	4	563	2e-47	187
tr:R4KED7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.22	426	279	10	261	676	13	434	2e-47	186
rs:WP_026824282	DNA topoisomerase III, partial [Arsenophonus nasoniae].	28.29	615	401	14	93	673	18	626	2e-47	188
rs:WP_006531800	DNA topoisomerase [Streptococcus infantarius].	28.11	594	372	18	3	574	4	564	2e-47	187
tr:W0WJX7_PSEAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.51	456	296	11	1	434	1	448	2e-47	185
rs:WP_022267008	DNA topoisomerase [Firmicutes bacterium CAG:449].	27.07	687	445	18	31	678	5	674	2e-47	188
gp:CP003859_761	DNA topoisomerase III [Streptococcus constellatus subsp. pharyngis C1050]	28.07	595	370	17	3	574	8	567	2e-47	187
rs:WP_023237100	DNA topoisomerase, partial [Salmonella enterica].	27.17	692	433	25	1	640	1	673	2e-47	188
rs:WP_031485737	DNA topoisomerase I [Desulfovibrio frigidus].	26.09	686	436	20	1	640	1	661	2e-47	188
rs:WP_017168565	hypothetical protein, partial [Xanthomonas axonopodis].	30.81	344	211	9	1	325	1	336	2e-47	181
tr:A0A0C7LW27_CLOSO	SubName: Full=TopA_3 protein {ECO:0000313|EMBL:CEP45829.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEP45829.1};	27.59	725	442	24	2	682	3	688	2e-47	188
rs:WP_041285285	DNA topoisomerase III, partial [Desulfotomaculum gibsoniae].	31.22	426	279	10	261	676	1	422	2e-47	186
tr:A0A015PAY0_BACFG	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EXY30277.1}; Flags: Fragment;	26.86	566	364	15	31	571	16	556	2e-47	186
rs:WP_037608064	DNA topoisomerase [Streptococcus sp. CM7].	28.07	595	370	17	3	574	4	563	2e-47	186
rs:WP_045362785	DNA topoisomerase III [Enterobacter aerogenes].	26.36	770	458	28	1	673	1	758	2e-47	188
rs:WP_025479193	DNA topoisomerase, partial [Enterococcus faecium].	28.39	546	353	11	3	520	4	539	2e-47	186
rs:WP_032582746	DNA topoisomerase I, partial [Bacteroides fragilis].	27.39	566	384	15	130	684	9	558	3e-47	186
rs:WP_012368885	DNA topoisomerase III [Proteus mirabilis].	26.97	697	439	24	1	646	1	678	3e-47	188
rs:WP_005945902	hypothetical protein, partial [Blautia hydrogenotrophica].	28.41	535	321	14	3	480	6	535	3e-47	186
rs:WP_044720911	DNA topoisomerase [Streptococcus suis].	28.45	594	370	18	3	574	4	564	3e-47	186
rs:WP_021539434	hypothetical protein [Escherichia coli].	26.59	737	468	23	1	683	1	718	3e-47	188
tr:X8JXS9_9STRE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.07	595	370	17	3	574	8	567	3e-47	186
rs:WP_043010875	DNA topoisomerase III [Campylobacter jejuni].	30.81	555	328	17	161	669	43	587	3e-47	187
rs:WP_017168920	hypothetical protein, partial [Xanthomonas axonopodis].	30.81	344	211	9	1	325	1	336	3e-47	181
rs:WP_023408496	hypothetical protein [uncultured Desulfofustis sp. PB-SRB1].	33.41	422	229	14	3	385	6	414	3e-47	183
rs:WP_043013020	DNA topoisomerase III [Clostridium perfringens].	27.08	709	454	23	1	667	2	689	3e-47	187
rs:WP_043037304	DNA topoisomerase [Streptococcus equi].	28.91	595	366	18	3	574	4	564	3e-47	186
rs:WP_010939590	DNA topoisomerase III [Desulfovibrio vulgaris].	27.29	480	313	13	224	673	322	795	4e-47	189
rs:WP_010939590	DNA topoisomerase III [Desulfovibrio vulgaris].	34.51	226	137	5	3	224	5	223	2e-31	140
rs:WP_042967269	DNA topoisomerase III [Escherichia coli].	26.12	735	480	22	1	687	1	720	4e-47	187
rs:WP_012961408	DNA topoisomerase III [Streptococcus gallolyticus].	28.74	602	358	20	3	574	8	568	4e-47	186
rs:WP_034037945	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	27.81	525	332	15	151	641	3	514	4e-47	185
tr:B1BR51_CLOPF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.08	709	454	23	1	667	1	688	4e-47	187
rs:WP_034233149	DNA topoisomerase III [Lachnospiraceae bacterium AC2029].	24.93	686	408	21	2	594	3	674	4e-47	187
rs:WP_015695732	DNA topoisomerase [Streptococcus infantarius].	28.28	594	371	18	3	574	4	564	4e-47	186
rs:WP_016271548	DNA topoisomerase III [Bacteroides vulgatus].	25.33	600	403	15	1	582	1	573	4e-47	186
rs:WP_031236772	DNA topoisomerase III, partial [Salmonella enterica].	26.18	573	374	13	46	578	1	564	4e-47	186
rs:WP_031611768	DNA topoisomerase III, partial [Salmonella enterica].	31.41	538	325	14	162	663	1	530	4e-47	185
rs:WP_024269854	DNA topoisomerase III [Clostridium perfringens].	28.53	722	442	24	2	680	3	693	4e-47	187
rs:WP_037599285	DNA topoisomerase [Streptococcus sp. ACS2].	28.14	597	369	19	3	574	5	566	4e-47	186
rs:WP_029662198	DNA topoisomerase III [Streptococcus agalactiae].	28.40	595	369	19	3	574	11	571	4e-47	186
rs:WP_009121355	DNA topoisomerase III [Bacteroides clarus].	26.09	617	399	16	1	593	1	584	4e-47	186
rs:WP_040411739	DNA topoisomerase III [[Clostridium] asparagiforme].	26.53	671	389	21	3	578	5	666	5e-47	187
tr:F5X1Y0_STRPX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.19	555	339	17	41	574	7	528	5e-47	185
tr:C0D086_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.53	671	389	21	3	578	9	670	5e-47	187
rs:WP_022178733	DNA topoisomerase [Firmicutes bacterium CAG:582].	27.86	725	461	22	1	684	1	704	5e-47	187
rs:WP_021326569	DNA topoisomerase III, partial [Photorhabdus temperata].	29.15	470	294	13	1	443	1	458	5e-47	183
rs:WP_031910263	DNA topoisomerase III, partial [Staphylococcus aureus].	31.45	461	275	13	173	615	1	438	6e-47	184
rs:WP_011791944	DNA topoisomerase III [Desulfovibrio vulgaris].	27.29	480	313	13	224	673	322	795	6e-47	188
rs:WP_011791944	DNA topoisomerase III [Desulfovibrio vulgaris].	34.51	226	137	5	3	224	5	223	5e-31	140
rs:WP_024343926	DNA topoisomerase [Streptococcus equinus].	28.57	595	368	19	3	574	4	564	6e-47	185
rs:WP_022146082	DNA topoisomerase [Firmicutes bacterium CAG:238].	26.33	733	469	25	3	687	4	713	7e-47	187
rs:WP_034918008	DNA topoisomerase III, partial [Candidatus Accumulibacter sp. BA-91].	27.66	564	339	21	163	676	1	545	8e-47	186
rs:WP_003230046	DNA topoisomerase III [Pseudomonas fluorescens].	24.00	725	494	17	1	684	1	709	9e-47	186
rs:WP_041639329	DNA topoisomerase III, partial [Anoxybacillus flavithermus].	32.34	334	208	8	3	327	4	328	9e-47	179
rs:WP_010215518	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	29.08	502	319	12	157	629	44	537	1e-46	184
rs:WP_000520753	hypothetical protein, partial [Bacillus cereus].	29.15	542	350	17	41	561	46	574	1e-46	184
rs:WP_023847589	DNA topoisomerase I, partial [Porphyromonas gingivalis].	31.72	413	248	12	1	394	1	398	1e-46	181
rs:WP_031826169	DNA topoisomerase III, partial [Staphylococcus aureus].	33.95	380	225	13	3	369	4	370	1e-46	180
tr:W1E140_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.53	346	215	9	245	581	54	393	1e-46	182
rs:WP_031811100	DNA topoisomerase III, partial [Staphylococcus aureus].	33.95	380	225	13	3	369	4	370	1e-46	180
rs:WP_029800262	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	30.17	421	256	11	2	390	3	417	1e-46	182
rs:WP_033858676	DNA topoisomerase III, partial [Staphylococcus aureus].	31.61	446	265	12	188	615	13	436	1e-46	184
rs:WP_013701945	DNA topoisomerase III [Treponema succinifaciens].	26.75	714	448	22	3	677	2	679	1e-46	186
rs:WP_031786141	DNA topoisomerase III, partial [Staphylococcus aureus].	31.61	446	265	12	188	615	14	437	1e-46	184
rs:WP_010968273	DNA topoisomerase III [Clostridium perfringens].	28.29	721	445	23	2	680	3	693	1e-46	186
rs:WP_002337938	DNA topoisomerase III [Enterococcus faecium].	27.98	679	427	22	41	687	44	692	1e-46	186
rs:WP_002318450	DNA topoisomerase, partial [Enterococcus faecium].	28.52	547	350	13	161	680	12	544	2e-46	184
tr:W4QCD4_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.36	377	231	14	3	365	5	371	2e-46	180
rs:WP_000280356	hypothetical protein [Bacillus cereus].	26.00	727	459	23	1	661	1	714	2e-46	186
rs:WP_036962358	DNA topoisomerase III [Providencia alcalifaciens].	26.71	700	437	26	1	646	1	678	2e-46	186
rs:WP_015336640	DNA topoisomerase type IA central domain protein [Desulfovibrio hydrothermalis].	24.76	719	473	19	1	672	1	698	2e-46	185
rs:WP_033160575	DNA topoisomerase I, partial [Bacteroides cellulosilyticus].	27.16	497	343	10	189	677	16	501	2e-46	182
tr:N1ZFX7_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	36.33	311	177	9	1	305	1	296	2e-46	177
rs:WP_037993304	DNA topoisomerase III, partial [Tannerella sp. oral taxon BU063].	33.65	315	195	7	1	310	1	306	2e-46	177
rs:WP_033624355	DNA topoisomerase, partial [Enterococcus faecium].	27.98	679	427	22	41	687	44	692	2e-46	185
rs:WP_036031200	hypothetical protein, partial [Burkholderia gladioli].	28.46	499	310	13	96	561	8	492	2e-46	182
rs:WP_002678088	DNA topoisomerase [Capnocytophaga sputigena].	27.86	718	442	28	3	673	5	693	3e-46	185
tr:W4LYF2_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.43	329	199	9	3	321	4	322	3e-46	178
tr:X7RGR9_VIBPH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.58	681	432	24	1	631	15	677	3e-46	185
rs:WP_031480058	DNA topoisomerase I [Desulfovibrio frigidus].	25.62	687	438	20	1	640	1	661	3e-46	185
rs:WP_033678243	DNA topoisomerase I [Bacillus gaemokensis].	26.55	708	475	20	3	681	5	696	3e-46	186
rs:WP_042631280	DNA topoisomerase III [Bacillus cereus].	26.00	727	459	23	1	661	1	714	3e-46	185
rs:WP_010776949	DNA topoisomerase III [Enterococcus faecium].	27.88	678	429	22	41	687	44	692	3e-46	185
tr:Q33E26_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.98	679	427	22	41	687	44	692	3e-46	185
rs:WP_042770153	DNA topoisomerase III [Vibrio parahaemolyticus].	26.58	681	432	24	1	631	1	663	3e-46	185
rs:WP_010200379	DNA topoisomerase III, partial [Pseudomonas amygdali].	27.68	466	301	11	157	592	22	481	3e-46	182
rs:WP_027859721	DNA topoisomerase III [Marinobacterium jannaschii].	25.08	622	427	15	1	596	6	614	3e-46	184
rs:WP_022757655	hypothetical protein [Butyrivibrio fibrisolvens].	24.48	715	482	23	1	680	1	692	3e-46	184
rs:WP_002311832	DNA topoisomerase [Enterococcus faecium].	27.98	679	427	22	41	687	44	692	3e-46	185
rs:WP_040101183	DNA topoisomerase III, partial [Escherichia coli].	30.20	553	342	13	157	673	20	564	4e-46	183
rs:WP_016241259	DNA topoisomerase III [Escherichia coli].	29.84	553	344	13	157	673	30	574	4e-46	183
rs:WP_024418977	DNA topoisomerase [Streptococcus suis].	27.41	602	375	16	3	579	4	568	4e-46	183
rs:WP_000463492	DNA topoisomerase III, partial [Salmonella enterica].	26.80	571	342	16	172	678	1	559	4e-46	182
tr:R4NN51_CLOBO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.21	447	278	11	200	627	1	441	4e-46	182
rs:WP_010719185	DNA topoisomerase III [Enterococcus hirae].	26.63	706	424	22	3	675	4	648	4e-46	184
rs:WP_009419771	DNA topoisomerase [Capnocytophaga sp. oral taxon 380].	27.82	719	441	28	3	673	5	693	4e-46	184
rs:WP_004461109	DNA topoisomerase III [Clostridium perfringens].	28.43	721	444	23	2	680	3	693	5e-46	184
rs:WP_045715631	DNA topoisomerase III, partial [Salmonella enterica].	30.02	543	336	13	167	673	3	537	5e-46	182
rs:WP_036888889	DNA topoisomerase I, partial [Porphyromonas crevioricanis].	29.91	448	287	11	1	432	1	437	6e-46	181
tr:J8I0M2_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.83	460	272	14	193	627	20	467	6e-46	182
rs:WP_032312320	DNA topoisomerase III, partial [Escherichia coli].	30.02	553	343	13	157	673	45	589	6e-46	182
rs:WP_033713469	DNA topoisomerase III, partial [Bacillus cereus].	32.83	460	272	14	193	627	1	448	6e-46	181
tr:R8H0D5_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.83	460	272	14	193	627	24	471	6e-46	182
rs:WP_040103882	DNA topoisomerase III, partial [Paenibacillus polymyxa].	28.06	499	317	14	111	577	1	489	6e-46	183
tr:W1HRD3_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.21	507	316	15	1	471	1	495	7e-46	181
rs:WP_038729615	DNA topoisomerase [Burkholderia sp. ABCPW 1].	25.51	682	408	25	2	610	3	657	7e-46	183
rs:WP_044163783	DNA topoisomerase I [Bacteroides reticulotermitis].	25.54	607	397	16	1	582	1	577	7e-46	182
rs:WP_008645707	hypothetical protein, partial [Bacteroides sp. 1_1_30].	31.64	414	249	12	1	394	1	400	7e-46	180
rs:WP_033715361	DNA topoisomerase III, partial [Bacillus cereus].	32.83	460	272	14	193	627	10	457	7e-46	181
rs:WP_042866226	DNA topoisomerase III [Bacillus cereus].	26.36	607	376	15	124	676	1	590	8e-46	183
rs:WP_023161792	DNA topoisomerase [Clostridium autoethanogenum].	28.11	683	429	25	3	649	4	660	8e-46	184
rs:WP_042260024	DNA topoisomerase III [Clostridium perfringens].	27.93	691	442	20	25	680	11	680	8e-46	183
rs:WP_036592880	DNA topoisomerase III, partial [Paenibacillus sophorae].	34.92	315	191	8	3	311	4	310	8e-46	176
tr:A0A0D5VWU6_XANCI	SubName: Full=DNA topoisomerase III, bacteria and conjugative plasmid {ECO:0000313|EMBL:AJZ66613.1};	29.54	413	261	12	1	391	1	405	9e-46	178
tr:C2TQW3_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.11	701	444	22	27	661	18	710	9e-46	183
rs:WP_031855974	DNA topoisomerase III [Vibrio parahaemolyticus].	26.40	678	437	23	1	631	1	663	9e-46	183
rs:WP_038486864	DNA topoisomerase III, partial [Halomonas campaniensis].	30.85	389	247	7	188	560	7	389	9e-46	179
rs:WP_017111690	hypothetical protein [Vibrio tasmaniensis].	26.46	718	463	23	1	668	1	703	1e-45	183
rs:WP_024668910	DNA topoisomerase III, partial [Pseudomonas syringae].	27.82	611	375	21	1	562	1	594	1e-45	182
rs:WP_033602985	DNA topoisomerase, partial [Enterococcus faecalis].	28.06	563	352	17	117	641	4	551	1e-45	181
rs:WP_031921622	DNA topoisomerase III, partial [Staphylococcus aureus].	31.31	444	265	12	190	615	1	422	1e-45	181
rs:WP_000165790	DNA topoisomerase III [Bacillus thuringiensis].	28.67	600	370	18	130	683	7	594	1e-45	183
tr:W4UVJ6_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.54	607	397	16	1	582	11	587	1e-45	182
rs:WP_041197081	DNA topoisomerase [Burkholderia pseudomallei].	25.51	682	408	24	2	610	3	657	1e-45	183
tr:G9QFT9_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.04	567	343	19	157	680	1	545	1e-45	181
rs:WP_008018278	DNA topoisomerase, partial [Bacteroides xylanisolvens].	29.54	457	301	10	86	530	17	464	1e-45	179
tr:D1AS14_SEBTE	SubName: Full=DNA topoisomerase type IA central domain protein {ECO:0000313|EMBL:ACZ11001.1};	28.80	677	423	25	1	640	1	655	1e-45	183
rs:WP_013238946	hypothetical protein [Clostridium ljungdahlii].	28.11	683	429	25	3	649	4	660	1e-45	183
rs:WP_031909847	DNA topoisomerase III, partial [Staphylococcus aureus].	30.12	498	313	13	3	479	4	487	1e-45	179
rs:WP_024666679	DNA topoisomerase III, partial [Pseudomonas syringae].	26.95	486	319	11	130	585	7	486	1e-45	181
tr:Q4MMD9_BACCE	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:AJI07793.1};	32.63	377	234	9	1	359	1	375	2e-45	177
rs:WP_031811082	DNA topoisomerase III, partial [Staphylococcus aureus].	28.44	538	356	12	100	620	11	536	2e-45	181
rs:WP_001689493	DNA topoisomerase, partial [Escherichia coli].	30.60	562	335	15	150	668	31	580	2e-45	181
rs:WP_008656087	DNA topoisomerase I [Bacteroides sp. 3_1_33FAA].	25.41	606	408	15	85	680	37	608	2e-45	182
rs:WP_006439044	DNA topoisomerase III [[Clostridium] hiranonis].	24.74	760	467	24	1	678	1	737	2e-45	182
rs:WP_044652667	DNA topoisomerase III, partial [Klebsiella variicola].	33.33	342	213	9	249	581	3	338	2e-45	176
tr:A0A0D0HY40_BACTM	SubName: Full=Bacillus thuringiensis serovar morrisoni strain HD 600 BG10.Contig244, whole genome shotgun sequence {ECO:0000313|EMBL:KIP25139.1};	36.06	330	188	12	3	321	5	322	2e-45	175
rs:WP_016478637	DNA topoisomerase III [Capnocytophaga sp. oral taxon 336].	27.69	715	447	26	3	673	5	693	2e-45	182
tr:W4LDQ7_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.64	327	197	9	5	321	1	317	2e-45	176
rs:WP_044119591	DNA topoisomerase, partial [Staphylococcus aureus].	28.34	547	339	17	117	625	4	535	2e-45	180
rs:WP_012248288	hypothetical protein, partial [Bordetella petrii].	28.92	408	250	10	1	381	1	395	3e-45	176
rs:WP_034276065	DNA topoisomerase III, partial [Bacillus sp. 171095_106].	35.12	336	191	8	1	317	1	328	3e-45	176
tr:F9RIF7_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.33	733	449	28	1	671	2	705	3e-45	182
rs:WP_022775098	hypothetical protein [Butyrivibrio sp. AE2015].	25.38	721	464	27	3	680	4	693	3e-45	181
rs:WP_041189026	DNA topoisomerase [Burkholderia pseudomallei].	25.37	682	409	24	2	610	3	657	3e-45	181
rs:WP_029642229	DNA topoisomerase III, partial [Acinetobacter baumannii].	27.62	478	310	12	172	614	1	477	3e-45	179
rs:WP_042120515	DNA topoisomerase I, partial [Porphyromonas crevioricanis].	29.46	448	289	11	1	432	1	437	3e-45	178
rs:WP_040757782	DNA topoisomerase III, partial [Vibrio scophthalmi].	26.33	733	449	28	1	671	1	704	4e-45	181
rs:WP_031420250	DNA topoisomerase III [Vibrio parahaemolyticus].	26.25	678	438	23	1	631	1	663	4e-45	181
rs:WP_044275906	hypothetical protein, partial [Burkholderia gladioli].	28.04	567	336	18	3	514	7	556	4e-45	179
tr:R8UL10_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.83	574	349	15	157	676	3	559	4e-45	181
rs:WP_035342059	DNA topoisomerase III, partial [Dickeya sp. DW 0440].	29.55	396	261	7	198	581	8	397	4e-45	177
rs:WP_033389182	topoisomerase I, partial [Lactobacillus parabrevis].	28.93	439	278	10	167	581	3	431	4e-45	179
rs:WP_031649805	DNA topoisomerase III, partial [Listeria innocua].	31.60	443	264	11	204	627	1	423	4e-45	179
rs:WP_026045081	DNA topoisomerase [Burkholderia pyrrocinia].	24.85	648	430	23	3	610	4	634	5e-45	181
rs:WP_002362705	DNA topoisomerase [Enterococcus faecium].	27.73	678	430	22	41	687	44	692	6e-45	181
rs:WP_044356048	DNA topoisomerase III, partial [Paenibacillus sp. E194].	34.25	327	194	9	3	319	4	319	6e-45	173
rs:WP_041311293	hypothetical protein, partial [Sebaldella termitidis].	29.08	643	404	22	1	611	1	623	6e-45	180
rs:WP_033017353	DNA topoisomerase III, partial [Geobacillus stearothermophilus].	36.31	336	197	6	71	391	1	334	6e-45	175
rs:WP_033669627	DNA topoisomerase III, partial [Bacillus cereus].	34.65	329	202	7	1	317	1	328	6e-45	174
rs:WP_023625372	hypothetical protein, partial [Clostridium tyrobutyricum].	31.70	407	254	11	1	393	1	397	7e-45	176
rs:WP_042677102	DNA topoisomerase III, partial [Pantoea sp. B40].	31.28	406	233	10	143	518	15	404	7e-45	176
tr:A4MY79_HAEIF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.38	427	256	12	188	583	18	438	7e-45	177
rs:WP_006749824	DNA topoisomerase III [Burkholderia ambifaria].	24.42	647	435	20	2	610	3	633	7e-45	180
rs:WP_005965580	DNA topoisomerase [Fusobacterium periodonticum].	27.58	736	456	25	1	687	1	708	8e-45	180
rs:WP_024409560	DNA topoisomerase [Streptococcus suis].	27.24	602	376	16	3	579	4	568	8e-45	179
tr:R8S7W4_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.65	329	202	7	1	317	1	328	9e-45	174
rs:WP_032946806	MULTISPECIES: DNA topoisomerase I [Bacteroides].	25.36	619	405	15	1	595	1	586	9e-45	179
rs:WP_031921360	DNA topoisomerase III, partial [Staphylococcus aureus].	32.18	404	254	10	157	550	7	400	1e-44	175
rs:WP_034303586	DNA topoisomerase III, partial [Bacillus sp. 123MFChir2].	32.19	379	237	9	1	361	1	377	1e-44	174
rs:WP_035066874	hypothetical protein, partial [Carnobacterium maltaromaticum].	27.07	687	427	22	3	655	5	651	1e-44	179
rs:WP_044270718	DNA topoisomerase I [Candidatus Bacteroides timonensis].	26.22	595	386	17	1	571	1	566	1e-44	179
rs:WP_028828555	DNA topoisomerase III [Proteocatella sphenisci].	31.96	413	251	12	2	397	3	402	1e-44	180
rs:WP_010218667	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	28.35	455	289	12	1	429	1	444	1e-44	177
rs:WP_033649945	DNA topoisomerase, partial [Enterococcus sp. GMD1E].	28.05	517	330	12	3	490	4	507	1e-44	177
rs:WP_002597132	hypothetical protein [Clostridium colicanis].	27.24	613	386	18	109	676	5	602	1e-44	179
tr:J8F712_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.84	486	291	16	41	490	45	516	1e-44	177
rs:WP_033644788	DNA topoisomerase, partial [Enterococcus faecium].	34.83	333	192	6	103	429	1	314	1e-44	173
tr:N0DX73_STRPY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.57	595	368	18	3	574	19	579	1e-44	178
rs:WP_039980728	DNA topoisomerase III [Vibrio sagamiensis].	27.38	694	427	28	1	640	1	671	1e-44	180
rs:WP_025831016	DNA topoisomerase III [Bacteroides stercorirosoris].	25.78	609	389	18	1	582	1	573	1e-44	178
rs:WP_006714456	DNA topoisomerase III [Vibrio ichthyoenteri].	25.44	621	410	19	1	580	1	609	2e-44	179
tr:H1HW63_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.31	631	381	19	65	622	16	635	2e-44	179
rs:WP_023198293	DNA topoisomerase III, partial [Salmonella enterica].	30.65	372	246	8	245	608	11	378	2e-44	174
rs:WP_045409866	DNA topoisomerase III [Vibrio jasicida].	26.35	687	443	24	1	640	1	671	2e-44	179
rs:WP_042712403	DNA topoisomerase III, partial [Klebsiella cf. planticola B43].	34.11	343	195	12	1	318	1	337	2e-44	173
tr:A0A078T205_9PORP	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:KDS67260.1};	26.21	580	386	16	34	594	1	557	2e-44	177
rs:WP_036764085	DNA topoisomerase [Peptostreptococcus sp. MV1].	24.97	773	456	25	1	676	1	746	2e-44	179
tr:A0A031KIR6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	34.83	333	192	6	103	429	1	314	2e-44	173
rs:WP_036381281	hypothetical protein [Mogibacterium timidum].	26.21	721	459	26	3	676	5	699	2e-44	179
rs:WP_032361994	DNA topoisomerase III, partial [Escherichia coli].	28.37	564	354	15	1	525	1	553	2e-44	177
rs:WP_025789167	DNA topoisomerase III [Vibrio parahaemolyticus].	26.03	680	437	23	1	631	1	663	2e-44	179
rs:WP_023251690	DNA topoisomerase III, partial [Salmonella enterica].	31.98	344	223	7	245	581	18	357	2e-44	174
rs:WP_031500110	DNA topoisomerase III [Vibrio parahaemolyticus].	26.03	680	437	23	1	631	1	663	2e-44	179
rs:WP_010726543	DNA topoisomerase III [Enterococcus faecium].	27.12	612	381	19	3	578	4	586	2e-44	179
rs:WP_002887270	topoisomerase IA [Streptococcus salivarius].	25.69	689	414	24	30	633	32	707	2e-44	179
rs:WP_029865550	DNA topoisomerase III [Vibrio parahaemolyticus].	26.14	681	435	24	1	631	1	663	2e-44	179
rs:WP_033911109	conjugal transfer protein TraE, partial [Neisseria gonorrhoeae].	27.43	565	369	14	2	530	3	562	2e-44	177
rs:WP_043043642	hypothetical protein, partial [Streptococcus equi].	25.66	643	433	12	1	615	1	626	3e-44	178
rs:WP_021914626	DNA topoisomerase [Firmicutes bacterium CAG:24].	27.01	648	374	22	41	596	12	652	3e-44	178
rs:WP_045422785	DNA topoisomerase III [Vibrio jasicida].	26.75	673	433	21	1	630	1	656	3e-44	179
rs:WP_012443232	DNA topoisomerase III [Erwinia tasmaniensis].	26.93	661	418	22	1	614	1	643	3e-44	179
rs:WP_033611595	DNA topoisomerase, partial [Enterococcus faecium].	27.12	612	381	19	3	578	4	586	3e-44	178
rs:WP_032707380	DNA topoisomerase III, partial [Pseudomonas savastanoi].	26.46	635	413	16	93	684	1	624	3e-44	178
rs:WP_042897089	DNA topoisomerase III, partial [Enterobacter aerogenes].	25.53	748	451	25	28	678	1	739	3e-44	179
rs:WP_021113548	DNA topoisomerase III family protein, partial [Haemophilus parasuis].	30.33	399	240	14	1	368	1	392	3e-44	173
rs:WP_040087766	DNA topoisomerase [Lactococcus garvieae].	28.74	595	363	17	3	573	4	561	4e-44	177
rs:WP_005636823	MULTISPECIES: DNA topoisomerase III [Bacteroidales].	25.50	604	397	16	1	582	1	573	4e-44	177
tr:E7PTU5_PSESG	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFW82968.1};	26.59	628	407	16	100	684	8	624	4e-44	177
rs:WP_031613135	DNA topoisomerase III, partial [Salmonella enterica].	31.98	344	223	7	245	581	51	390	4e-44	174
rs:WP_031557102	DNA topoisomerase III [Lachnospiraceae bacterium FD2005].	26.13	662	400	20	3	580	5	661	4e-44	178
rs:WP_045402153	DNA topoisomerase III [Vibrio campbellii].	25.47	687	449	23	1	640	1	671	4e-44	178
rs:WP_027433226	DNA topoisomerase III [Lachnospiraceae bacterium MD2004].	26.24	663	398	20	3	580	5	661	4e-44	178
rs:WP_017144927	DNA topoisomerase [Fusobacterium nucleatum].	26.59	737	463	27	1	687	1	709	4e-44	178
rs:WP_022085420	DNA topoisomerase [Roseburia sp. CAG:197].	24.96	693	414	19	93	686	1	686	4e-44	181
rs:WP_005790119	MULTISPECIES: DNA topoisomerase III [Bacteroides].	26.24	606	390	19	1	582	1	573	4e-44	177
tr:D4JW68_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.17	715	472	21	1	673	1	694	4e-44	179
rs:WP_032889348	DNA topoisomerase [Fusobacterium nucleatum].	26.59	737	463	24	1	687	1	709	4e-44	178
rs:WP_029505782	DNA topoisomerase III [Lachnospiraceae bacterium AC2012].	26.40	663	397	22	3	580	5	661	5e-44	178
tr:V2LUX5_SALET	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	34.01	344	194	13	1	318	1	337	5e-44	172
tr:D4E5Q2_SEROD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.99	342	229	5	245	581	27	366	5e-44	174
rs:WP_045716821	DNA topoisomerase III, partial [Salmonella enterica].	31.98	344	223	7	245	581	56	395	5e-44	174
rs:WP_000165792	DNA topoisomerase III [Bacillus cereus].	27.83	600	375	18	130	683	7	594	6e-44	177
rs:WP_004234233	DNA topoisomerase III [Streptococcus parauberis].	28.74	595	363	17	3	573	4	561	6e-44	176
rs:WP_031890592	DNA topoisomerase III, partial [Staphylococcus aureus].	29.21	493	329	9	100	580	11	495	6e-44	175
rs:WP_009244366	DNA topoisomerase III [Lachnospiraceae bacterium 2_1_58FAA].	27.35	585	364	18	65	594	1	579	6e-44	176
tr:W1AZV1_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.69	344	224	7	245	581	47	386	7e-44	173
rs:WP_038888830	DNA topoisomerase III [Vibrio campbellii].	26.09	621	409	18	1	579	1	613	7e-44	177
rs:WP_045417592	DNA topoisomerase III [Vibrio owensii].	25.47	687	449	23	1	640	1	671	7e-44	177
rs:WP_025818807	DNA topoisomerase III [Vibrio parahaemolyticus].	25.62	687	448	23	1	640	1	671	8e-44	177
rs:WP_044707711	DNA topoisomerase III, partial [Escherichia coli].	31.69	344	224	7	245	581	55	394	8e-44	173
rs:WP_024700499	DNA topoisomerase III [Vibrio parahaemolyticus].	26.03	680	437	23	1	631	1	663	9e-44	177
rs:WP_003105435	DNA topoisomerase [Streptococcus parauberis].	28.57	595	364	17	3	573	4	561	9e-44	176
tr:V2BXS5_SALDE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.01	344	194	13	1	318	1	337	9e-44	172
rs:WP_025789708	DNA topoisomerase III [Vibrio parahaemolyticus].	25.62	687	448	23	1	640	1	671	9e-44	177
rs:WP_045368045	DNA topoisomerase III [Vibrio campbellii].	25.59	723	466	26	1	671	1	703	9e-44	177
rs:WP_042775760	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	26.15	654	422	21	1	610	1	637	9e-44	176
rs:WP_012219851	DNA topoisomerase III [Vibrio sp. 23023].	25.91	687	446	23	1	640	1	671	9e-44	177
rs:WP_001263213	DNA topoisomerase III [Vibrio sp. RC341].	26.16	688	443	24	1	640	1	671	9e-44	177
rs:WP_017187990	DNA topoisomerase III [Vibrio harveyi].	26.84	693	432	26	1	640	1	671	1e-43	177
rs:WP_031500043	DNA topoisomerase III [Vibrio parahaemolyticus].	25.88	680	438	23	1	631	1	663	1e-43	177
rs:WP_009411156	DNA topoisomerase [Capnocytophaga sp. oral taxon 324].	27.74	721	441	29	3	673	4	694	1e-43	177
tr:C3HV26_BACTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.72	454	271	13	200	627	1	441	1e-43	174
tr:G9QZP7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.15	328	188	11	3	317	5	317	1e-43	170
rs:WP_032106904	DNA topoisomerase III, partial [Escherichia coli].	31.69	344	224	7	245	581	24	363	1e-43	172
rs:WP_021769906	DNA topoisomerase III [Leptotrichia sp. oral taxon 225].	27.98	704	440	28	2	675	3	669	1e-43	176
rs:WP_006773686	DNA topoisomerase III, partial [[Clostridium] hathewayi].	29.48	502	323	11	188	671	5	493	1e-43	174
rs:WP_027829209	hypothetical protein [Lactobacillus harbinensis].	24.96	709	476	17	4	684	6	686	2e-43	176
rs:WP_027633415	hypothetical protein [Clostridium hydrogeniformans].	25.07	686	433	21	3	652	16	656	2e-43	176
tr:W1FAC4_ENTCL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.53	343	197	12	1	318	1	337	2e-43	171
rs:WP_005828774	MULTISPECIES: DNA topoisomerase III [Bacteroides].	26.04	599	400	15	1	582	1	573	2e-43	175
rs:WP_033694665	DNA topoisomerase III, partial [Bacillus thuringiensis].	33.33	348	192	6	72	391	1	336	2e-43	171
rs:WP_025068471	hypothetical protein, partial [Prevotella denticola].	34.86	327	191	8	4	317	5	322	2e-43	169
rs:WP_045492443	DNA topoisomerase III [Vibrio sp. 151112A].	25.33	687	450	23	1	640	1	671	2e-43	176
rs:WP_025480915	DNA topoisomerase, partial [Enterococcus faecalis].	28.32	512	318	15	154	629	5	503	2e-43	173
rs:WP_001701798	DNA topoisomerase III, partial [Salmonella enterica].	33.33	327	206	8	262	581	3	324	2e-43	170
rs:WP_022409634	DNA topoisomerase [Clostridium sp. CAG:354].	26.72	726	453	26	3	679	5	700	2e-43	176
rs:WP_047021715	topoisomerase I, partial [Lactobacillus brevis].	28.47	439	280	10	167	581	3	431	3e-43	174
tr:A0A090R3W2_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.90	348	219	7	251	585	16	358	3e-43	171
rs:WP_002311029	DNA topoisomerase [Enterococcus faecium].	31.37	424	266	8	103	511	3	416	3e-43	173
tr:R4EHX8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.32	512	318	15	154	629	1	499	3e-43	173
rs:WP_015769197	DNA topoisomerase III [Leptotrichia buccalis].	28.47	706	434	29	2	675	3	669	3e-43	175
rs:WP_001840255	DNA topoisomerase III, partial [Salmonella enterica].	33.82	343	194	13	1	317	1	336	3e-43	169
rs:WP_021970827	DNA topoisomerase [Bacteroides sp. CAG:1076].	30.71	407	260	7	193	588	1	396	3e-43	173
tr:W1EWP4_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.77	384	226	15	1	355	1	377	3e-43	171
rs:WP_033603659	DNA topoisomerase, partial [Enterococcus faecalis].	28.32	512	318	15	154	629	20	518	3e-43	173
rs:WP_033623889	DNA topoisomerase, partial [Enterococcus faecalis].	27.95	526	328	14	188	675	1	513	3e-43	173
rs:WP_035016504	DNA topoisomerase, partial [Enterococcus raffinosus].	29.26	499	321	12	3	476	4	495	3e-43	172
rs:WP_021639560	toprim domain protein, partial [Clostridium sp. KLE 1755].	40.27	226	117	6	1	219	1	215	3e-43	166
rs:WP_025788905	DNA topoisomerase III [Vibrio parahaemolyticus].	25.41	736	462	25	1	675	1	710	4e-43	176
rs:WP_001727078	DNA topoisomerase III, partial [Salmonella enterica].	32.92	322	205	7	267	581	1	318	4e-43	169
tr:K1TYJ3_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC78082.1}; Flags: Fragment;	31.86	295	182	7	1	290	1	281	4e-43	167
rs:WP_003106651	DNA topoisomerase III [Streptococcus parauberis].	28.40	595	365	17	3	573	4	561	4e-43	174
rs:WP_021747026	DNA topoisomerase III [Leptotrichia wadei].	28.02	703	441	27	2	675	3	669	4e-43	175
rs:WP_022524170	DNA topoisomerase III [Halomonas sp. A3H3].	26.83	615	364	24	41	581	43	645	4e-43	176
rs:WP_023036564	hypothetical protein [Fusobacterium nucleatum].	27.19	743	451	28	1	687	1	709	4e-43	175
tr:C7VPQ1_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.95	526	328	14	188	675	12	524	5e-43	173
rs:WP_033615871	DNA topoisomerase, partial [Enterococcus faecium].	28.32	512	318	15	154	629	20	518	5e-43	172
rs:WP_044102072	DNA topoisomerase III, partial [Xanthomonas citri].	29.06	406	254	12	1	382	1	396	5e-43	170
rs:WP_006073986	DNA topoisomerase III [Vibrio shilonii].	26.56	689	439	25	1	640	1	671	5e-43	175
rs:WP_039139562	DNA topoisomerase III, partial [Gallibacterium anatis].	29.43	418	263	8	193	581	1	415	5e-43	171
rs:WP_021744852	DNA topoisomerase III [Leptotrichia sp. oral taxon 879].	27.98	704	440	28	2	675	3	669	6e-43	174
rs:WP_005430719	DNA topoisomerase III [Vibrio campbellii].	25.14	728	463	25	1	671	1	703	6e-43	175
tr:R2RVG6_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.26	499	321	12	3	476	4	495	6e-43	172
rs:WP_031410708	DNA topoisomerase III [Vibrio parahaemolyticus].	25.81	678	441	23	1	631	1	663	6e-43	175
rs:WP_005942683	DNA topoisomerase III [Bacteroides massiliensis].	25.33	600	403	16	1	582	1	573	7e-43	173
sp:TOP1_PYRHO	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	26.28	681	423	22	1	639	1	644	7e-43	174
rs:WP_033572549	DNA topoisomerase I [Bacteroides sp. UW].	25.86	607	391	20	1	582	1	573	8e-43	173
rs:WP_016121531	DNA topoisomerase 3, partial [Bacillus cereus].	34.98	323	187	12	3	314	5	315	8e-43	167
rs:WP_008778772	DNA topoisomerase III [Parabacteroides sp. 20_3].	25.59	598	404	17	1	582	1	573	9e-43	173
rs:WP_010783371	DNA topoisomerase III, partial [Enterococcus faecalis].	27.65	528	331	14	186	675	7	521	9e-43	172
tr:A0A0A2V3B3_BEABA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.74	438	240	15	3	398	5	425	9e-43	170
rs:WP_041619455	DNA topoisomerase III, partial [Paenibacillus mucilaginosus].	33.66	410	235	16	3	393	4	395	1e-42	171
rs:WP_016220726	DNA topoisomerase III, partial [Dorea sp. 5-2].	33.55	313	183	9	1	305	1	296	1e-42	166
rs:WP_007219031	DNA topoisomerase III [Bacteroides cellulosilyticus].	25.86	607	391	20	1	582	1	573	1e-42	172
rs:WP_012816677	DNA topoisomerase III [Staphylococcus aureus].	30.70	456	286	12	3	437	4	450	1e-42	170
tr:A0A073I7K6_9PORP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.86	607	391	20	1	582	1	573	1e-42	172
rs:WP_039542348	DNA topoisomerase III [Vibrio vulnificus].	26.06	687	445	24	1	640	1	671	1e-42	174
rs:WP_002366151	DNA topoisomerase, partial [Enterococcus faecium].	26.81	552	349	14	158	667	23	561	1e-42	172
rs:WP_008675116	DNA topoisomerase III [Bacteroides sp. 9_1_42FAA].	25.86	607	391	20	1	582	1	573	1e-42	172
rs:WP_036756511	hypothetical protein [Photobacterium halotolerans].	26.54	618	388	17	1	565	1	605	1e-42	175
rs:WP_004407605	DNA topoisomerase III, partial [Pseudomonas syringae].	29.97	387	237	12	1	363	1	377	1e-42	168
rs:WP_027702382	DNA topoisomerase [[Clostridium] mangenotii].	28.66	621	386	22	1	592	1	593	1e-42	174
rs:WP_044860248	DNA topoisomerase III, partial [Enterobacter cloacae].	33.53	340	195	12	3	317	1	334	1e-42	167
rs:WP_038228795	DNA topoisomerase III [Vibrio sp. ER1A].	26.42	689	440	25	1	640	1	671	2e-42	174
rs:WP_024727418	hypothetical protein [Clostridiales bacterium VE202-09].	26.50	668	401	28	40	656	65	693	2e-42	173
rs:WP_016276248	DNA topoisomerase III, partial [Bacteroides massiliensis].	27.00	500	342	12	188	677	11	497	2e-42	171
tr:X7RXE5_FUSNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.27	671	410	26	1	636	1	628	2e-42	173
rs:WP_032890733	DNA topoisomerase [Fusobacterium nucleatum].	27.27	671	410	26	1	636	5	632	2e-42	173
tr:U5SB31_9LACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.37	380	224	10	2	361	6	372	2e-42	167
rs:WP_029491379	DNA topoisomerase [Fusobacterium hwasookii].	26.46	737	464	25	1	687	1	709	2e-42	173
rs:WP_024469514	hypothetical protein [Treponema pedis].	26.43	719	450	27	1	680	1	679	2e-42	173
rs:WP_018675578	hypothetical protein [Riemerella columbina].	28.40	514	337	16	174	673	10	506	2e-42	171
rs:WP_043945782	DNA topoisomerase III, partial [Carnobacterium sp. WN1359].	32.37	380	224	10	2	361	3	369	2e-42	167
rs:WP_002322285	DNA topoisomerase, partial [Enterococcus faecium].	27.73	541	338	16	109	611	9	534	2e-42	171
rs:WP_002322390	DNA topoisomerase, partial [Enterococcus faecium].	27.73	541	338	16	109	611	10	535	2e-42	171
rs:WP_000165791	DNA topoisomerase III [Bacillus thuringiensis].	27.50	600	377	18	130	683	7	594	2e-42	172
rs:WP_032598760	DNA topoisomerase I [Bacteroides fragilis].	25.66	604	396	17	1	582	1	573	2e-42	171
rs:WP_031929814	DNA topoisomerase, partial [Staphylococcus aureus].	28.35	508	315	15	154	625	13	507	2e-42	170
rs:WP_020367711	hypothetical protein, partial [Staphylococcus epidermidis].	30.16	451	268	13	161	581	22	455	2e-42	169
tr:X1JH75_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S15831 {ECO:0000313|EMBL:GAH69093.1}; Flags: Fragment;	35.32	269	163	5	69	334	1	261	3e-42	164
rs:WP_008693641	type I topoisomease [Fusobacterium nucleatum].	26.85	663	423	23	1	636	5	632	3e-42	172
rs:WP_044478145	DNA topoisomerase III, partial [Peptoclostridium difficile].	39.38	226	118	7	1	218	1	215	3e-42	162
rs:WP_039635672	hypothetical protein [Clostridium argentinense].	32.77	470	256	17	157	574	52	513	3e-42	171
rs:WP_010733726	MULTISPECIES: DNA topoisomerase III, partial [Enterococcus].	27.73	512	321	14	154	629	13	511	3e-42	170
sp:TOP1_PYRAB	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	27.18	688	413	24	1	639	1	649	3e-42	172
rs:WP_000165793	hypothetical protein [Bacillus cereus].	27.67	600	376	17	130	683	7	594	3e-42	172
rs:WP_005846717	MULTISPECIES: DNA topoisomerase III [Bacteroides].	25.16	612	401	18	1	588	1	579	4e-42	171
rs:WP_014611673	DNA topoisomerase [Shewanella putrefaciens].	26.38	633	404	19	1	580	1	624	4e-42	172
rs:WP_044243489	DNA topoisomerase III, partial [Pantoea stewartii].	27.49	622	394	16	2	581	3	609	4e-42	171
rs:WP_005945111	DNA topoisomerase, partial [Faecalibacterium prausnitzii].	29.76	467	280	15	105	548	18	459	4e-42	169
tr:A0A061PB57_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.33	455	279	12	248	680	14	452	4e-42	169
rs:WP_026748846	DNA topoisomerase III [Leptotrichia trevisanii].	28.07	709	433	31	2	675	3	669	5e-42	172
rs:WP_029740844	DNA topoisomerase III, partial [Enterobacter asburiae].	27.62	525	330	15	1	491	1	509	5e-42	170
rs:WP_005594981	DNA topoisomerase III, partial [Vibrio scophthalmi].	26.44	662	424	22	28	640	16	663	5e-42	172
rs:WP_010782941	DNA topoisomerase III, partial [Enterococcus faecalis].	28.01	507	337	11	130	620	20	514	5e-42	170
rs:WP_005307127	DNA topoisomerase III [Photobacterium damselae].	25.44	688	442	23	1	640	1	665	6e-42	172
tr:J6CXX6_PASMD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.46	453	242	18	1	399	1	434	6e-42	169
tr:G6C564_9FUSO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHI77883.1};	26.91	721	445	25	1	669	15	705	6e-42	172
tr:F9EMU8_FUSNU	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EGQ79718.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EGQ79718.1};	25.85	735	471	24	1	687	6	714	6e-42	171
rs:WP_044860249	DNA topoisomerase III, partial [Enterobacter cloacae].	33.24	340	196	12	3	317	1	334	7e-42	165
rs:WP_035495790	DNA topoisomerase [Fusobacterium sp. oral taxon 370].	26.98	719	447	25	1	669	1	691	7e-42	171
tr:A0A0A0M4X3_9LACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.79	480	311	14	41	499	21	495	8e-42	169
rs:WP_020325450	hypothetical protein, partial [Pseudomonas syringae].	27.46	579	358	19	1	532	1	564	8e-42	169
rs:WP_033655835	DNA topoisomerase, partial [Enterococcus faecium].	27.65	528	331	14	186	675	14	528	8e-42	169
rs:WP_017161855	hypothetical protein, partial [Xanthomonas axonopodis].	29.72	323	201	8	1	305	1	315	8e-42	164
tr:L2H5I4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.65	528	331	14	186	675	13	527	8e-42	169
rs:WP_046058708	DNA topoisomerase III, partial [Clostridium sp. IBUN13A].	31.31	412	260	9	216	615	1	401	9e-42	169
tr:W8A717_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.71	505	323	15	3	481	4	497	9e-42	169
tr:A0A0D1K8U8_9LACT	SubName: Full=TopB_3 protein {ECO:0000313|EMBL:KIU21474.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIU21474.1};	30.13	468	293	14	3	444	4	463	9e-42	168
rs:WP_014003991	DNA topoisomerase [Pseudomonas putida].	25.37	737	438	33	32	687	33	738	9e-42	172
rs:WP_025983421	DNA topoisomerase III [Vibrio parahaemolyticus].	25.11	677	447	22	1	631	1	663	9e-42	171
tr:H6NHR0_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.42	407	236	15	3	391	4	393	1e-41	171
rs:WP_017144917	DNA topoisomerase [Fusobacterium nucleatum].	26.91	747	446	29	1	686	1	708	1e-41	171
rs:WP_011998820	DNA topoisomerase III [Vibrio campbellii].	25.59	723	466	27	1	671	1	703	1e-41	171
tr:A0A061Q3G6_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.24	733	455	26	1	671	1	702	1e-41	171
rs:WP_023039571	hypothetical protein [Fusobacterium nucleatum].	27.26	730	431	29	1	669	1	691	1e-41	171
rs:WP_046420451	DNA topoisomerase, partial [Xylella fastidiosa].	29.86	422	271	11	233	630	11	431	1e-41	167
rs:WP_022300463	DNA topoisomerase III [Erysipelotrichaceae bacterium CAG:64].	26.20	626	387	17	93	661	3	610	1e-41	170
tr:A0A080LRY5_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.12	531	328	19	189	676	15	529	1e-41	170
tr:B7IYV7_BACC2	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.10	573	354	17	157	683	27	587	1e-41	170
tr:A0A097QU60_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.72	726	391	26	3	639	4	677	2e-41	170
tr:E0H2D5_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.77	447	251	15	3	413	4	432	2e-41	166
rs:WP_032532316	hypothetical protein, partial [Streptococcus suis].	27.45	601	366	19	3	571	4	566	2e-41	169
tr:F0H7Y1_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EGC86078.1};	28.88	509	306	17	190	673	1	478	2e-41	167
rs:WP_036869100	DNA topoisomerase I, partial [Prevotella bivia].	28.60	507	305	14	193	673	1	476	2e-41	167
rs:WP_045424446	DNA topoisomerase III [Vibrio jasicida].	25.63	679	438	24	1	630	1	661	2e-41	170
rs:WP_000864636	DNA topoisomerase [Bacillus cereus].	29.14	429	266	9	1	400	1	420	2e-41	167
rs:WP_031872897	DNA topoisomerase III, partial [Staphylococcus aureus].	30.86	444	277	12	3	425	4	438	2e-41	166
rs:WP_034945828	DNA topoisomerase III, partial [Erwinia oleae].	29.17	384	237	11	1	359	1	374	2e-41	165
rs:WP_034706710	DNA topoisomerase, partial [Enterococcus gallinarum].	32.47	425	233	15	3	391	4	410	2e-41	166
rs:WP_042743737	DNA topoisomerase III, partial [Staphylococcus aureus].	30.86	444	277	12	3	425	4	438	2e-41	166
tr:U7TAX9_FUSNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.55	663	425	23	1	636	1	628	2e-41	170
rs:WP_044456500	DNA topoisomerase, partial [Bacillus subtilis].	29.56	477	287	14	3	446	4	464	2e-41	167
rs:WP_032880430	DNA topoisomerase [Fusobacterium nucleatum].	26.55	663	425	23	1	636	5	632	2e-41	169
rs:WP_005898479	DNA topoisomerase [Fusobacterium nucleatum].	26.42	738	463	25	1	687	1	709	2e-41	170
rs:WP_024380179	hypothetical protein [Streptococcus suis].	28.15	604	358	20	3	571	4	566	3e-41	168
rs:WP_043308972	hypothetical protein, partial [Bacillus sp. 7_6_55CFAA_CT2].	27.95	576	367	16	108	655	3	558	3e-41	170
rs:WP_032946566	DNA topoisomerase I, partial [Bacteroides vulgatus].	27.79	529	341	13	79	593	2	503	3e-41	167
rs:WP_023043299	DNA topoisomerase III, partial [Enterococcus faecium].	26.98	504	330	11	3	478	4	497	3e-41	167
rs:WP_022954113	conjugal transfer protein TraE [Leucothrix mucor].	24.92	610	399	17	41	612	37	625	3e-41	170
rs:WP_008799063	type I topoisomease [Fusobacterium nucleatum].	26.70	663	424	23	1	636	5	632	3e-41	169
rs:WP_042562302	hypothetical protein [Yersinia frederiksenii].	25.38	654	431	17	3	614	4	642	3e-41	170
tr:C7DGI7_MICA2	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.85	674	414	22	3	638	4	636	3e-41	169
rs:WP_031935420	DNA topoisomerase III, partial [Escherichia coli].	32.11	355	210	13	41	367	7	358	3e-41	164
rs:WP_004362759	hypothetical protein [Prevotella nigrescens].	33.75	323	194	7	1	311	2	316	3e-41	162
rs:WP_025017587	DNA topoisomerase III [Bacteroides sartorii].	25.00	604	400	15	1	582	1	573	3e-41	168
rs:WP_033692241	hypothetical protein, partial [Bacillus sp. GeD10].	26.08	510	341	8	1	481	1	503	4e-41	167
tr:B7BDS6_9PORP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.78	522	339	19	171	676	1	500	4e-41	167
rs:WP_009682480	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	25.23	757	470	32	3	687	5	737	4e-41	171
rs:WP_044803320	DNA topoisomerase III, partial [Bacillus amyloliquefaciens].	34.56	379	213	12	271	627	2	367	4e-41	166
rs:WP_029739023	DNA topoisomerase, partial [Enterococcus faecalis].	32.24	425	234	15	3	391	4	410	4e-41	165
rs:WP_021639559	DNA topoisomerase, partial [Clostridium sp. KLE 1755].	30.45	440	280	10	251	673	1	431	4e-41	166
tr:W6P9Q2_9BACE	SubName: Full=DNA topoisomerase III, Bacteroidales-type {ECO:0000313|EMBL:CDM06736.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDM06736.1};	30.10	412	268	13	274	677	2	401	4e-41	165
rs:WP_044342681	DNA topoisomerase III [Pseudomonas oryzihabitans].	24.60	695	437	26	15	643	14	687	4e-41	170
rs:WP_008701260	DNA topoisomerase III [Fusobacterium nucleatum].	26.21	660	431	21	1	636	5	632	5e-41	169
rs:WP_038231122	DNA topoisomerase, partial [Xylella fastidiosa].	32.56	347	200	9	5	324	5	344	5e-41	163
rs:WP_032212589	DNA topoisomerase III, partial [Escherichia coli].	31.20	407	249	14	100	479	11	413	6e-41	164
tr:K1RSX6_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC46549.1}; Flags: Fragment;	31.40	430	265	11	265	673	9	429	6e-41	165
rs:WP_038284267	DNA topoisomerase, partial [Xylella fastidiosa].	32.56	347	200	9	5	324	5	344	6e-41	162
tr:U7T468_FUSNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.21	660	431	21	1	636	1	628	6e-41	168
tr:R3GZL3_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.99	322	200	7	2	315	5	315	6e-41	162
rs:WP_002405920	DNA topoisomerase, partial [Enterococcus faecalis].	30.63	480	278	16	3	446	4	464	6e-41	166
tr:A0A090QXC2_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.38	341	204	9	2	318	3	337	6e-41	163
rs:WP_009336444	hypothetical protein, partial [Bacillus sp. 2_A_57_CT2].	30.62	418	252	11	3	392	5	412	6e-41	166
rs:WP_038233057	DNA topoisomerase, partial [Xylella fastidiosa].	32.56	347	200	9	5	324	5	344	6e-41	162
gp:CP007064_1426	DNA topoisomerase III [Fusobacterium nucleatum subsp. vincentii 3_1_27]	26.55	663	425	23	1	636	1	628	6e-41	168
rs:WP_009640589	DNA topoisomerase [Capnocytophaga sp. CM59].	27.39	723	454	26	3	680	5	701	6e-41	169
rs:WP_031860929	DNA topoisomerase III, partial [Staphylococcus aureus].	31.29	425	262	12	3	406	4	419	6e-41	164
rs:WP_042688973	DNA topoisomerase I [Thermococcus nautili].	26.48	725	398	24	3	639	4	681	6e-41	169
rs:WP_008797619	type I topoisomerase [Fusobacterium nucleatum].	26.55	663	425	23	1	636	5	632	7e-41	168
rs:WP_031837088	DNA topoisomerase III, partial [Staphylococcus aureus].	35.28	326	192	10	3	321	4	317	7e-41	162
rs:WP_014121655	DNA topoisomerase I [Thermococcus sp. AM4].	26.48	725	398	24	3	639	4	681	8e-41	168
tr:W3Z2X6_9FUSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.70	663	424	23	1	636	1	628	8e-41	168
rs:WP_031875882	DNA topoisomerase III, partial [Staphylococcus aureus].	35.28	326	192	10	3	321	4	317	9e-41	162
rs:WP_032840587	DNA topoisomerase [Fusobacterium sp. CM21].	26.70	663	424	23	1	636	5	632	9e-41	168
rs:WP_031860269	DNA topoisomerase III, partial [Staphylococcus aureus].	35.28	326	192	10	3	321	4	317	1e-40	162
tr:K1SDD2_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC45401.1}; Flags: Fragment;	32.42	330	204	6	1	318	1	323	1e-40	162
rs:WP_031923560	DNA topoisomerase III, partial [Staphylococcus aureus].	32.59	405	243	12	3	386	4	399	1e-40	163
rs:WP_033624195	DNA topoisomerase, partial [Enterococcus faecium].	31.76	425	236	15	3	391	4	410	1e-40	164
rs:WP_031892888	DNA topoisomerase III, partial [Staphylococcus aureus].	35.28	326	192	10	3	321	4	317	1e-40	162
rs:XP_001786801	predicted protein [Physcomitrella patens].	28.67	429	268	9	119	528	1	410	1e-40	163
rs:WP_005656946	DNA topoisomerase III [Bacteroides stercoris].	24.96	601	404	16	1	582	1	573	1e-40	166
rs:WP_008800967	DNA topoisomerase III [Fusobacterium gonidiaformans].	25.30	656	430	17	1	625	1	627	1e-40	168
rs:WP_044325068	DNA topoisomerase III, partial [Pseudomonas amygdali].	29.61	439	281	9	260	673	19	454	1e-40	164
rs:WP_023926566	hypothetical protein [Prevotella nigrescens].	33.44	320	193	7	4	311	5	316	2e-40	160
rs:WP_014343005	DNA topoisomerase III [Klebsiella pneumoniae].	33.43	338	185	13	1	309	1	327	2e-40	162
rs:WP_013702783	DNA topoisomerase [Treponema succinifaciens].	26.67	615	379	24	3	579	2	582	2e-40	166
tr:C3DEJ5_BACTS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.25	388	228	11	261	627	3	380	2e-40	164
rs:WP_008778583	DNA topoisomerase III [Parabacteroides sp. 20_3].	25.71	599	402	15	1	582	1	573	2e-40	166
tr:K1TSU6_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC76072.1}; Flags: Fragment;	28.57	385	256	7	95	468	4	380	2e-40	163
tr:A0A0B4ISV6_VIBHA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.46	711	453	27	1	653	1	692	2e-40	167
rs:WP_033801728	DNA topoisomerase III, partial [Escherichia coli].	28.54	515	333	13	1	488	1	507	2e-40	164
tr:F3FB75_PSEA0	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.85	468	298	12	188	629	15	473	2e-40	164
rs:WP_042775764	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	27.35	563	362	17	1	526	1	553	3e-40	165
rs:WP_008802445	type I topoisomease [Fusobacterium nucleatum].	26.70	663	424	23	1	636	5	632	3e-40	166
rs:WP_039842175	DNA topoisomerase III [Vibrio owensii].	24.90	727	466	25	1	671	1	703	3e-40	167
rs:WP_014733804	DNA topoisomerase I [Pyrococcus sp. ST04].	26.01	692	420	22	1	639	1	653	3e-40	166
rs:WP_019484415	hypothetical protein, partial [Pseudomonas aeruginosa].	27.72	386	247	8	65	425	17	395	4e-40	162
tr:E1YRP3_9PORP	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFK63720.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFK63720.1};	29.34	467	297	16	229	684	12	456	4e-40	163
rs:WP_001235759	DNA topoisomerase III, partial [Escherichia coli].	28.68	516	331	14	1	488	1	507	4e-40	164
rs:WP_025991918	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	27.95	458	298	14	50	479	1	454	4e-40	162
rs:WP_008781114	DNA topoisomerase III [Bacteroides sp. 3_1_19].	25.71	599	402	15	1	582	1	573	4e-40	165
tr:U7TS60_FUSNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.24	663	427	23	1	636	1	628	5e-40	166
tr:K8CP04_CROSK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.19	310	162	13	41	318	2	301	5e-40	159
tr:R8QQ81_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.17	529	323	17	189	680	13	521	5e-40	164
rs:WP_031868979	DNA topoisomerase III, partial [Staphylococcus aureus].	30.86	418	249	12	216	615	1	396	5e-40	163
rs:WP_033714660	DNA topoisomerase III, partial [Bacillus cereus].	28.17	529	323	17	189	680	2	510	5e-40	164
rs:WP_034018007	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	27.50	531	339	13	188	680	2	524	5e-40	164
rs:WP_032893455	DNA topoisomerase [Fusobacterium nucleatum].	26.24	663	427	23	1	636	5	632	6e-40	165
tr:A0A011P1L8_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.19	459	265	16	87	500	2	445	6e-40	163
tr:E1GTM7_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFN91994.1};	30.02	413	262	12	271	673	45	440	6e-40	162
rs:WP_042744581	topoisomerase I, partial [Oenococcus oeni].	29.44	462	305	11	3	445	4	463	6e-40	163
rs:WP_016228891	hypothetical protein [Lachnospiraceae bacterium 10-1].	28.68	544	344	16	157	679	39	559	7e-40	164
rs:WP_045418085	DNA topoisomerase III [Vibrio owensii].	25.34	726	462	27	1	671	1	701	7e-40	166
rs:WP_002348823	DNA topoisomerase, partial [Enterococcus faecium].	27.01	522	325	14	158	639	23	528	7e-40	163
tr:M2PJT3_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EMD15854.1};	39.83	231	125	6	1	226	1	222	7e-40	157
rs:WP_042225960	DNA topoisomerase I, partial [Porphyromonas cansulci].	28.40	486	315	14	219	684	9	481	8e-40	162
rs:WP_013293439	DNA topoisomerase [Gallionella capsiferriformans].	25.33	600	358	17	5	580	19	552	8e-40	163
rs:WP_044858971	DNA topoisomerase III, partial [Enterobacter cloacae].	32.05	312	201	7	277	581	1	308	9e-40	159
rs:WP_024599854	hypothetical protein [Pseudoalteromonas haloplanktis].	32.02	331	191	8	1	305	1	323	9e-40	159
rs:WP_032991710	DNA topoisomerase III, partial [Cronobacter dublinensis].	33.98	309	164	12	41	318	2	301	1e-39	158
rs:WP_023052298	hypothetical protein [Cetobacterium somerae].	25.23	769	449	24	1	671	1	741	1e-39	166
rs:WP_032881383	DNA topoisomerase [Fusobacterium nucleatum].	26.40	663	426	23	1	636	5	632	1e-39	164
rs:WP_010601443	DNA topoisomerase type IA central domain-containing protein, partial [Pedobacter agri].	26.85	447	307	12	150	582	2	442	1e-39	162
tr:U2AIP4_XYLFS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.02	321	186	8	31	324	6	324	1e-39	158
rs:WP_015858922	DNA topoisomerase I [Thermococcus gammatolerans].	26.46	718	400	25	3	639	4	674	1e-39	165
tr:U7T6W8_FUSNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.40	663	426	23	1	636	1	628	2e-39	164
rs:WP_039086265	conjugal transfer protein TraE, partial [Gallibacterium anatis].	29.95	424	267	10	1	400	1	418	2e-39	160
rs:WP_035561877	hypothetical protein [Halomonas sp. KO116].	26.32	585	355	21	41	563	43	613	2e-39	165
tr:W7C7N0_LISGR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.16	389	231	13	258	631	3	377	2e-39	161
rs:WP_042357400	DNA topoisomerase, partial [Streptococcus equi].	41.13	231	122	6	1	226	1	222	2e-39	156
rs:WP_032448662	DNA topoisomerase III, partial [Klebsiella pneumoniae].	28.00	550	348	20	1	511	1	541	2e-39	162
rs:WP_040202207	DNA topoisomerase III, partial [Klebsiella pneumoniae].	28.00	550	348	20	1	511	1	541	2e-39	162
rs:WP_040227468	hypothetical protein [Bhargavaea cecembensis].	31.50	381	239	9	261	627	1	373	2e-39	160
rs:WP_047184914	DNA topoisomerase III, partial [Bacilli bacterium VT-13-104].	30.95	378	227	14	3	361	5	367	3e-39	158
tr:C9LHI7_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEX71447.1};	30.86	431	263	13	257	673	59	468	3e-39	161
rs:WP_040176477	DNA topoisomerase III, partial [Klebsiella pneumoniae].	28.00	550	348	20	1	511	1	541	3e-39	162
tr:W4VNY9_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	32.50	320	199	9	3	314	5	315	3e-39	157
rs:WP_047338674	hypothetical protein [Enterococcus cecorum].	26.51	611	381	20	1	582	2	573	3e-39	162
rs:WP_032837319	DNA topoisomerase [Fusobacterium sp. CM1].	26.40	663	426	23	1	636	5	632	3e-39	163
tr:U3N9M1_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.25	443	283	10	248	673	2	435	4e-39	160
rs:WP_022211948	DNA topoisomerase [Clostridium sp. CAG:265].	32.23	394	214	15	2	359	3	379	4e-39	159
tr:F6IZ93_LACPE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.06	541	351	14	168	676	6	529	4e-39	161
tr:A0A090P8Q4_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.20	323	205	7	268	581	11	328	5e-39	158
tr:A0A0A7U5Q4_LACBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.09	413	267	9	189	581	3	405	6e-39	160
tr:X8ID75_9FUSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.40	663	426	23	1	636	1	628	6e-39	162
rs:WP_044988648	DNA topoisomerase III, partial [Tyzzerella nexilis].	28.92	453	279	13	31	440	7	459	7e-39	160
rs:WP_013293892	DNA topoisomerase [Gallionella capsiferriformans].	25.17	584	347	16	5	564	19	536	7e-39	160
rs:WP_031883559	DNA topoisomerase III, partial [Staphylococcus aureus].	30.18	434	263	12	200	615	1	412	8e-39	160
tr:B6FVP8_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	28.92	453	279	13	31	440	12	464	8e-39	160
rs:WP_044647931	DNA topoisomerase III, partial [Paenibacillus terrae].	30.03	383	242	9	1	361	1	379	8e-39	157
gp:CP008854_358	DNA topoisomerase III [Bacillus anthracis]	34.05	370	213	11	279	627	1	360	9e-39	159
tr:U2KBX5_9BACT	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:ERJ72353.1};	31.56	320	199	6	4	311	5	316	1e-38	155
rs:WP_036869692	DNA topoisomerase I, partial [Prevotella disiens].	31.56	320	199	6	4	311	5	316	1e-38	155
tr:S4EDR9_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.86	542	346	16	167	673	2	533	1e-38	160
rs:WP_035725181	DNA topoisomerase III, partial [Gracilibacillus boraciitolerans].	32.49	317	197	9	3	311	5	312	1e-38	155
rs:WP_036887869	DNA topoisomerase I, partial [Prevotella bivia].	32.93	328	192	9	4	311	5	324	1e-38	155
rs:WP_023195012	DNA topoisomerase III, partial [Salmonella enterica].	30.47	338	223	8	279	608	1	334	1e-38	156
rs:WP_005747021	DNA topoisomerase III, partial [Pseudomonas amygdali].	29.44	360	224	10	31	365	12	366	1e-38	157
rs:WP_046337887	DNA topoisomerase III, partial [Xenorhabdus bovienii].	31.94	335	209	7	288	614	1	324	1e-38	157
rs:WP_031904996	DNA topoisomerase III, partial [Staphylococcus aureus].	32.81	384	228	12	3	365	4	378	1e-38	157
rs:WP_002352807	DNA topoisomerase, partial [Enterococcus faecium].	26.51	498	328	11	3	472	4	491	1e-38	159
rs:WP_009751280	DNA topoisomerase [Capnocytophaga sp. oral taxon 332].	27.20	739	440	28	3	680	5	706	1e-38	162
tr:L2JM52_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.68	542	347	16	167	673	2	533	1e-38	160
rs:WP_035476679	hypothetical protein [Burkholderia phenoliruptrix].	28.70	446	270	14	5	415	7	439	1e-38	159
rs:WP_031903950	DNA topoisomerase III, partial [Staphylococcus aureus].	28.27	474	312	11	163	620	13	474	2e-38	159
rs:WP_042700412	DNA topoisomerase I [Thermococcus sp. PK].	25.70	712	412	22	3	639	4	673	2e-38	161
rs:WP_002363152	DNA topoisomerase, partial [Enterococcus faecium].	26.56	497	327	11	3	471	4	490	2e-38	159
rs:WP_025140922	hypothetical protein [Achromobacter sp. DH1f].	26.02	565	354	16	83	594	80	633	2e-38	160
tr:E8TUJ8_ALIDB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.77	383	239	11	1	361	1	375	2e-38	156
rs:WP_045900057	DNA topoisomerase, partial [Enterobacter cloacae].	31.38	376	232	9	176	525	2	377	2e-38	156
rs:WP_036668036	topoisomerase I, partial [Pediococcus acidilactici].	27.12	413	271	8	189	581	3	405	2e-38	159
rs:WP_015062157	DNA topoisomerase III [Salmonella sp. 14].	28.25	485	320	13	3	463	6	486	2e-38	159
rs:WP_041716195	DNA topoisomerase III, partial [Alicycliphilus denitrificans].	31.56	339	206	9	1	321	1	331	2e-38	155
tr:R3UNR0_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.34	428	274	9	276	675	4	422	2e-38	157
rs:WP_013292672	DNA topoisomerase [Gallionella capsiferriformans].	25.78	578	339	17	5	558	19	530	3e-38	159
tr:E1KMG8_9BACT	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EFL47335.1};	34.13	334	188	10	4	315	5	328	3e-38	155
tr:N9XV23_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.78	574	371	16	1	541	1	552	3e-38	159
rs:WP_034948907	DNA topoisomerase III, partial [Erwinia oleae].	29.26	393	246	8	256	629	53	432	3e-38	157
rs:WP_044960508	DNA topoisomerase III [Faecalibacterium prausnitzii].	27.17	530	329	16	170	671	1	501	3e-38	158
rs:WP_040555347	DNA topoisomerase I, partial [Prevotella disiens].	34.24	330	185	10	4	311	5	324	3e-38	154
rs:WP_036859048	DNA topoisomerase I, partial [Prevotella disiens].	31.82	330	195	8	4	311	5	326	3e-38	154
rs:WP_036421357	DNA topoisomerase III, partial [Morganella morganii].	29.00	469	294	12	1	442	1	457	3e-38	157
rs:WP_024467148	hypothetical protein [Treponema pedis].	28.73	557	338	21	1	525	1	530	3e-38	158
rs:WP_017706786	DNA topoisomerase III, partial [Pseudomonas syringae].	28.46	390	241	11	1	364	1	378	4e-38	155
tr:H1HC00_FUSNU	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EHO79969.1}; Flags: Fragment;	26.58	666	420	23	69	687	1	644	4e-38	159
rs:WP_027851694	DNA topoisomerase III [Marinospirillum insulare].	25.72	622	387	16	31	590	31	639	4e-38	160
rs:WP_044345686	DNA topoisomerase III, partial [Pseudomonas meliae].	29.25	465	296	12	1	441	1	456	4e-38	157
rs:WP_000209234	DNA topoisomerase III, partial [Bacillus anthracis].	35.43	254	147	5	3	244	4	252	5e-38	152
tr:T2GJI9_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.93	675	399	24	2	631	3	621	5e-38	160
rs:WP_002359812	DNA topoisomerase, partial [Enterococcus faecium].	26.57	493	324	11	3	467	4	486	5e-38	157
rs:WP_036889217	DNA topoisomerase I, partial [Prevotella aurantiaca].	34.25	327	181	10	4	311	5	316	5e-38	153
tr:K1UD74_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC76190.1};	37.50	224	125	7	1	218	1	215	6e-38	151
rs:WP_034194827	hypothetical protein, partial [Burkholderia sp. WP42].	30.09	339	210	10	1	321	1	330	7e-38	154
rs:WP_031868977	DNA topoisomerase III, partial [Staphylococcus aureus].	34.70	317	188	10	3	312	4	308	8e-38	153
rs:WP_031894067	DNA topoisomerase III, partial [Staphylococcus aureus].	28.64	447	300	8	145	580	1	439	8e-38	156
sp:TOP1_METTH	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.92	683	404	25	2	639	10	635	8e-38	159
tr:A0A0B6X7U4_XENBV	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.76	340	213	7	283	614	166	494	8e-38	157
rs:WP_004312901	DNA topoisomerase, partial [Bacteroides xylanisolvens].	29.56	433	273	15	263	684	1	412	9e-38	155
tr:A0A078QP62_BACVU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.54	512	331	12	95	593	3	487	1e-37	156
rs:WP_036876890	DNA topoisomerase [Prevotella denticola].	28.82	451	275	12	241	673	46	468	1e-37	156
tr:W4RXJ6_9XANT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.32	343	209	8	65	383	17	353	1e-37	153
rs:WP_005352530	hypothetical protein [[Eubacterium] siraeum].	27.65	586	353	22	130	673	5	561	1e-37	158
rs:WP_010776959	DNA topoisomerase III, partial [Enterococcus faecium].	27.64	474	300	13	186	629	11	471	1e-37	156
rs:WP_036889220	DNA topoisomerase I, partial [Prevotella aurantiaca].	33.23	337	171	12	4	311	5	316	1e-37	152
rs:WP_035457587	topoisomerase I, partial [Lactobacillus coryniformis].	28.09	413	267	10	189	581	10	412	1e-37	156
tr:J2Z439_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.09	413	267	10	189	581	18	420	1e-37	157
rs:WP_023926537	hypothetical protein [Prevotella nigrescens].	33.03	330	191	8	4	311	5	326	1e-37	152
tr:R1VFV3_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.21	475	297	14	154	597	1	462	2e-37	155
rs:WP_005874995	hypothetical protein, partial [Enterococcus faecium].	28.06	449	273	12	208	644	4	414	2e-37	155
rs:WP_042664917	hypothetical protein [Thaumarchaeota archaeon SCGC AB-179-E04].	24.60	691	452	20	3	658	8	664	2e-37	158
rs:WP_031842635	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	32.13	305	199	6	262	560	8	310	2e-37	152
rs:WP_029657351	DNA topoisomerase, partial [Enterococcus faecalis].	28.21	475	297	14	154	597	20	481	2e-37	155
rs:WP_001678913	DNA topoisomerase III, partial [Salmonella enterica].	33.65	315	177	12	1	290	1	308	2e-37	151
rs:WP_033603135	DNA topoisomerase, partial [Enterococcus faecalis].	28.36	476	294	14	154	595	20	482	3e-37	155
rs:WP_016504282	DNA topoisomerase III, partial [Pasteurella multocida].	31.82	330	213	8	261	583	38	362	3e-37	153
rs:WP_036884824	DNA topoisomerase I, partial [Prevotella disiens].	32.75	342	174	11	4	311	5	324	3e-37	152
tr:J9GIY8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJX07582.1};	34.93	272	157	8	41	305	2	260	3e-37	150
rs:WP_011998043	DNA topoisomerase I [Ignicoccus hospitalis].	24.51	608	384	19	64	639	58	622	3e-37	157
rs:WP_031825299	DNA topoisomerase III, partial [Staphylococcus aureus].	34.49	316	188	10	3	311	4	307	3e-37	151
tr:D4KBC0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.49	536	332	15	170	673	1	506	4e-37	155
tr:A0A075LS84_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.56	712	418	22	3	639	4	678	4e-37	157
rs:WP_043895620	DNA topoisomerase I, partial [Porphyromonas gingivalis].	29.83	419	261	14	253	651	5	410	4e-37	153
rs:WP_036864533	DNA topoisomerase I, partial [Prevotella bivia].	32.19	320	197	7	4	311	5	316	4e-37	151
rs:WP_043881503	DNA topoisomerase III, partial [Vibrio cholerae].	31.01	345	204	10	2	318	3	341	4e-37	152
rs:WP_016355620	DNA topoisomerase [Pseudomonas migulae].	24.54	754	466	27	3	682	5	729	5e-37	158
tr:F7JP30_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.45	381	230	10	276	627	4	378	5e-37	154
tr:T0MS31_9SPHI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	34.06	320	190	7	1	307	1	312	5e-37	151
rs:WP_038231947	DNA topoisomerase, partial [Xylella fastidiosa].	32.24	335	193	9	5	312	5	332	6e-37	151
tr:K1U396_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC76693.1}; Flags: Fragment;	32.92	319	195	8	86	394	4	313	6e-37	151
gpu:CP009695_24	DNA topoisomerase family protein [Bacillus anthracis]	30.09	432	264	13	276	682	4	422	6e-37	153
tr:S5VD34_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.34	334	202	7	3	317	4	332	6e-37	151
tr:A0A0E1MML2_BACAN	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:AJH85612.1};	30.09	432	264	13	276	682	4	422	6e-37	153
tr:G9QDN0_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.79	560	363	14	124	655	1	541	6e-37	157
rs:WP_034428118	DNA topoisomerase, partial [Anaerococcus pacaensis].	33.79	293	178	7	1	290	1	280	6e-37	149
rs:WP_022010557	DNA topoisomerase [Firmicutes bacterium CAG:646].	29.41	459	275	12	200	627	1	441	7e-37	154
rs:WP_036891898	DNA topoisomerase I, partial [Prevotella corporis].	32.42	330	193	8	4	311	5	326	7e-37	150
tr:A0A069YSN5_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.02	496	323	12	1	470	1	488	7e-37	154
tr:L9PS42_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELX66474.1};	32.63	334	177	9	4	311	5	316	8e-37	150
rs:WP_033603300	DNA topoisomerase, partial [Enterococcus faecalis].	28.36	476	294	14	154	595	20	482	8e-37	154
rs:WP_031922934	DNA topoisomerase III, partial [Staphylococcus aureus].	32.65	340	193	9	293	615	1	321	8e-37	151
rs:WP_025480891	DNA topoisomerase, partial [Enterococcus faecium].	25.96	520	334	13	186	667	13	519	8e-37	155
rs:WP_036882142	DNA topoisomerase I, partial [Prevotella nigrescens].	32.63	334	177	9	4	311	5	316	8e-37	150
tr:G5S0U4_SALET	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.03	290	194	4	298	581	10	299	8e-37	152
rs:WP_036890994	DNA topoisomerase I, partial [Prevotella corporis].	32.42	330	193	8	4	311	5	326	9e-37	150
tr:J6WY89_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.96	520	334	13	186	667	13	519	9e-37	154
rs:WP_032190916	DNA topoisomerase III, partial [Escherichia coli].	33.02	315	179	12	1	290	1	308	9e-37	150
rs:WP_014788241	DNA topoisomerase I [Thermococcus sp. CL1].	25.53	748	413	25	3	660	4	697	1e-36	156
rs:WP_042080261	DNA topoisomerase III, partial [Escherichia coli].	32.50	320	184	12	1	295	1	313	1e-36	150
rs:WP_016301096	hypothetical protein [Lachnospiraceae bacterium COE1].	25.75	567	375	15	131	673	11	555	1e-36	155
tr:Q2B125_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EAR63544.1};	33.21	274	167	7	3	270	4	267	1e-36	149
rs:WP_029997262	DNA topoisomerase [Streptococcus suis].	26.32	608	379	19	1	578	2	570	1e-36	155
rs:WP_031826156	DNA topoisomerase III, partial [Staphylococcus aureus].	32.28	347	199	9	286	615	7	334	1e-36	152
tr:A0A090VZF4_9FLAO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL68624.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL68624.1};	38.50	226	110	7	1	212	1	211	1e-36	148
rs:WP_031811092	DNA topoisomerase III, partial [Staphylococcus aureus].	32.28	347	199	9	286	615	4	331	1e-36	152
tr:A0A015SDB8_BACFG	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EXY68292.1};	25.49	455	313	12	236	680	25	463	1e-36	153
rs:WP_008957431	DNA topoisomerase III [Halomonas sp. HAL1].	26.15	585	356	21	41	563	43	613	1e-36	157
rs:WP_026745683	DNA topoisomerase III [Leptotrichia hofstadii].	27.09	705	445	26	2	675	3	669	1e-36	155
rs:WP_040187426	DNA topoisomerase III, partial [Halomonas salina].	27.78	324	204	8	1	304	1	314	1e-36	149
rs:WP_040078239	DNA topoisomerase III, partial [Escherichia coli].	30.65	336	209	7	289	610	4	329	2e-36	151
rs:WP_019724267	hypothetical protein, partial [Enterococcus mundtii].	27.48	404	257	8	216	614	6	378	2e-36	153
rs:WP_031612378	DNA topoisomerase III, partial [Salmonella enterica].	31.76	340	198	10	1	318	1	328	2e-36	149
rs:WP_026191728	DNA topoisomerase III [Methylosinus sp. LW4].	25.48	577	384	18	44	581	30	599	2e-36	155
tr:S4NKE1_9PORP	SubName: Full=DNA topoisomerase III, Bacteroidales-type {ECO:0000313|EMBL:GAD07880.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAD07880.1};	28.73	442	283	13	263	684	2	431	2e-36	152
tr:L8JJT3_9BACT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ELR68513.1};	33.21	262	149	7	1	247	1	251	2e-36	147
tr:R8K356_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.03	446	301	10	244	675	13	452	2e-36	153
rs:WP_024389804	DNA topoisomerase [Streptococcus suis].	26.32	608	379	19	1	578	2	570	2e-36	154
rs:WP_033711194	DNA topoisomerase I, partial [Bacillus cereus].	28.03	446	301	10	244	675	28	467	2e-36	153
rs:WP_002353593	DNA topoisomerase, partial [Enterococcus faecium].	28.64	426	264	12	3	399	4	418	2e-36	152
rs:WP_032946838	hypothetical protein [Lactococcus lactis].	27.09	635	366	21	2	583	3	593	2e-36	154
tr:A0A090T775_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.62	369	208	12	161	493	14	370	2e-36	150
tr:S6EZC3_LACLL	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.50	629	371	22	2	583	7	597	2e-36	154
rs:WP_002360282	DNA topoisomerase, partial [Enterococcus faecium].	28.64	426	264	12	3	399	4	418	3e-36	152
rs:WP_012858882	DNA topoisomerase [Streptobacillus moniliformis].	30.35	402	252	11	1	395	1	381	3e-36	154
rs:WP_024417943	DNA topoisomerase [Streptococcus suis].	26.32	608	379	19	1	578	2	570	3e-36	153
rs:WP_042680133	DNA topoisomerase I [Thermococcus sp. ES1].	26.54	618	376	21	3	585	4	578	3e-36	155
tr:J8BJA9_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.03	446	301	10	244	675	13	452	3e-36	152
rs:WP_009436399	DNA topoisomerase III [Prevotella sp. oral taxon 473].	28.37	416	242	9	238	606	320	726	4e-36	155
rs:WP_009436399	DNA topoisomerase III [Prevotella sp. oral taxon 473].	33.47	236	148	3	1	228	1	235	1e-35	154
rs:WP_015791283	DNA topoisomerase I [Methanocaldococcus fervens].	27.72	707	414	23	3	668	4	654	4e-36	155
rs:WP_014012324	DNA topoisomerase I [Thermococcus sp. 4557].	24.86	740	431	22	3	660	4	700	4e-36	154
rs:WP_044314482	DNA topoisomerase III, partial [Pseudomonas stutzeri].	29.57	345	203	9	1	320	1	330	4e-36	149
rs:WP_037250833	MULTISPECIES: DNA topoisomerase III, partial [Roseomonas].	26.00	550	371	14	44	560	31	577	4e-36	154
rs:WP_002349797	DNA topoisomerase, partial [Enterococcus faecium].	29.31	389	240	10	3	366	4	382	4e-36	150
rs:WP_004816326	DNA topoisomerase, partial [Anaerococcus hydrogenalis].	33.62	351	202	12	251	590	42	372	4e-36	149
tr:T3QPZ8_PEPDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.43	359	196	12	287	631	2	331	5e-36	150
rs:WP_038230219	DNA topoisomerase, partial [Xylella fastidiosa].	31.94	335	194	9	5	312	5	332	5e-36	148
rs:WP_004666758	DNA topoisomerase III [Pseudomonas savastanoi].	24.27	754	468	27	3	682	5	729	5e-36	155
rs:WP_013329862	DNA topoisomerase I [Methanolacinia petrolearia].	24.14	700	422	30	1	650	1	641	5e-36	155
rs:WP_013466927	DNA topoisomerase I [Thermococcus barophilus].	24.93	742	423	26	3	655	4	700	6e-36	154
rs:WP_017707254	DNA topoisomerase III, partial [Pseudomonas syringae].	28.90	391	251	9	256	629	54	434	6e-36	150
rs:WP_036891772	DNA topoisomerase I, partial [Prevotella corporis].	32.50	320	196	7	4	311	5	316	6e-36	147
rs:WP_002384820	type 1 topoisomerase [Enterococcus faecalis].	27.01	411	263	9	293	675	54	455	7e-36	150
rs:WP_031929785	DNA topoisomerase, partial [Staphylococcus aureus].	27.01	411	263	9	293	675	27	428	7e-36	150
rs:WP_044954275	DNA topoisomerase III, partial [Faecalibacterium prausnitzii].	32.55	255	158	6	2	251	4	249	7e-36	146
rs:WP_002839970	toprim domain protein, partial [Finegoldia magna].	36.36	231	137	5	1	228	1	224	7e-36	145
rs:WP_000352443	DNA topoisomerase I, partial [Bacillus thuringiensis].	26.73	490	322	12	208	675	4	478	8e-36	153
tr:K1SYX7_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC52511.1}; Flags: Fragment;	36.63	243	143	6	86	325	1	235	8e-36	146
rs:WP_042932890	DNA topoisomerase III, partial [Pseudomonas coronafaciens].	28.90	391	251	9	256	629	7	387	8e-36	149
gp:CP006744_95	DNA topoisomerase [Bacillus anthracis str. SVA11]	29.86	432	265	13	276	682	4	422	9e-36	150
rs:WP_044677942	DNA topoisomerase [Streptococcus suis].	25.99	608	381	19	1	578	2	570	9e-36	152
rs:WP_042880445	hypothetical protein [Bacillus anthracis].	36.91	233	130	5	3	223	4	231	9e-36	145
tr:F2ZR01_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.90	391	251	9	256	629	16	396	9e-36	149
tr:W1FZU6_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	33.12	314	180	11	1	290	1	308	9e-36	147
rs:WP_004222575	DNA topoisomerase III [Bifidobacterium pseudocatenulatum].	31.63	313	198	10	1	306	1	304	9e-36	148
rs:WP_006734849	DNA topoisomerase [Lactobacillus iners].	26.20	752	472	28	3	687	4	739	1e-35	154
tr:C7YE99_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.62	417	269	9	287	675	59	466	1e-35	150
rs:WP_002349703	DNA topoisomerase, partial [Enterococcus faecium].	27.25	477	301	10	158	600	23	487	1e-35	150
rs:WP_002839237	DNA topoisomerase, partial [Finegoldia magna].	33.05	348	197	12	257	590	6	331	1e-35	147
rs:WP_029175409	DNA topoisomerase [Streptococcus suis].	26.15	608	380	19	1	578	2	570	1e-35	152
rs:WP_034284088	hypothetical protein [Aeromonas salmonicida].	36.89	225	121	5	1	211	1	218	1e-35	144
rs:WP_038952236	DNA topoisomerase III, partial [Bradyrhizobium japonicum].	25.28	534	355	15	82	581	71	594	1e-35	152
rs:WP_033617346	topoisomerase I, partial [Lactobacillus plantarum].	28.76	386	239	10	193	555	1	373	1e-35	148
rs:WP_044193063	DNA topoisomerase I, partial [Parabacteroides gordonii].	26.67	390	278	4	130	514	2	388	1e-35	148
rs:WP_044064261	DNA topoisomerase I, partial [Prevotella saccharolytica].	28.96	442	276	13	66	480	8	438	1e-35	149
rs:WP_036891111	DNA topoisomerase I, partial [Prevotella corporis].	32.05	337	175	10	4	311	5	316	1e-35	147
tr:A0A0E1RBZ5_ENTFL	SubName: Full=DNA Topoisomerase family protein {ECO:0000313|EMBL:CCO71514.1};	27.01	411	263	9	293	675	81	482	1e-35	150
rs:WP_028728974	DNA topoisomerase I, partial [Parabacteroides gordonii].	27.11	391	275	5	130	514	2	388	1e-35	148
rs:WP_011405969	DNA topoisomerase I [Methanosphaera stadtmanae].	26.04	676	395	29	2	629	3	621	2e-35	153
rs:WP_010716652	DNA topoisomerase III, partial [Enterococcus faecalis].	27.01	411	263	9	293	675	51	452	2e-35	149
rs:WP_012571272	DNA topoisomerase I [Thermococcus onnurineus].	24.90	715	419	22	3	640	4	677	2e-35	153
rs:WP_031860277	DNA topoisomerase III, partial [Staphylococcus aureus].	32.29	350	211	9	249	589	8	340	2e-35	147
tr:G2JB72_9BURK	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:CCD30025.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CCD30025.1};	28.74	421	260	14	2	391	4	415	2e-35	150
rs:WP_012859159	DNA topoisomerase [Streptobacillus moniliformis].	27.75	537	337	16	1	520	1	503	2e-35	152
rs:WP_001895995	DNA topoisomerase III, partial [Vibrio cholerae].	31.66	319	196	6	276	581	1	310	2e-35	147
rs:WP_031830982	hypothetical protein, partial [Vibrio parahaemolyticus].	29.06	382	228	12	32	379	1	373	2e-35	148
rs:WP_000596661	hypothetical protein, partial [Shigella boydii].	30.85	376	240	8	268	629	2	371	2e-35	148
rs:WP_046940204	hypothetical protein, partial [Xanthomonas euvesicatoria].	26.98	493	272	14	161	583	27	501	2e-35	151
rs:WP_029656423	DNA topoisomerase, partial [Enterococcus faecalis].	27.14	409	261	9	295	675	1	400	2e-35	148
rs:WP_029655836	MULTISPECIES: DNA topoisomerase, partial [Enterococcus].	27.14	409	261	9	295	675	1	400	2e-35	148
rs:WP_035976377	DNA topoisomerase III, partial [Bradyrhizobium sp. th.b2].	25.74	575	379	16	44	581	31	594	2e-35	152
rs:WP_020315918	DNA topoisomerase III, partial [Pseudomonas syringae].	29.77	346	211	9	1	325	1	335	2e-35	147
rs:WP_034284084	DNA topoisomerase, partial [Aeromonas salmonicida].	30.09	422	262	13	233	630	9	421	3e-35	149
tr:B2I572_XYLF2	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.69	309	179	8	31	312	6	312	3e-35	146
tr:L2JIY6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.11	517	337	12	186	667	18	524	3e-35	150
rs:WP_044650215	DNA topoisomerase III, partial [Klebsiella variicola].	33.65	312	167	13	1	283	1	301	3e-35	145
rs:WP_031892894	DNA topoisomerase III, partial [Staphylococcus aureus].	31.53	352	205	9	274	608	8	340	3e-35	146
rs:WP_032583404	DNA topoisomerase I, partial [Bacteroides fragilis].	28.61	395	247	14	289	666	1	377	3e-35	147
rs:WP_033616825	MULTISPECIES: DNA topoisomerase, partial [Enterococcus].	27.25	411	262	9	293	675	84	485	4e-35	149
tr:W4LTG6_9DELT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETX01011.1};	24.59	488	324	11	188	639	2	481	4e-35	150
rs:WP_041269880	DNA topoisomerase III, partial [Geobacillus sp. WCH70].	28.38	437	274	14	278	686	1	426	4e-35	148
rs:WP_036287960	DNA topoisomerase III [Methylosinus sp. PW1].	25.59	555	369	16	44	560	30	578	5e-35	151
rs:WP_013295046	DNA topoisomerase I [Methanothermobacter marburgensis].	26.19	672	416	27	2	639	3	628	5e-35	151
rs:WP_029656583	DNA topoisomerase, partial [Enterococcus faecalis].	27.25	411	262	9	293	675	84	485	5e-35	149
tr:G0QAX5_NANSJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.95	605	389	18	3	585	4	571	5e-35	151
tr:E2ZN64_9FIRM	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EFQ05379.1}; Flags: Fragment;	32.41	253	157	6	4	251	1	244	5e-35	143
rs:WP_043199706	DNA topoisomerase III [Bradyrhizobium sp. URHA0002].	24.92	646	415	19	44	627	31	668	6e-35	152
rs:WP_033609362	topoisomerase I, partial [Lactobacillus plantarum].	33.33	330	204	9	3	317	4	332	7e-35	146
rs:WP_032739622	DNA topoisomerase III, partial [Klebsiella pneumoniae].	31.50	327	200	11	298	615	8	319	7e-35	145
rs:WP_021676309	toprim domain protein, partial [Peptostreptococcaceae bacterium oral taxon 113].	40.69	204	107	6	3	201	4	198	7e-35	141
rs:WP_015017538	DNA topoisomerase IA [Candidatus Nitrososphaera gargensis].	26.23	648	398	25	3	612	4	609	7e-35	150
rs:WP_023650177	DNA topoisomerase III family protein, partial [Vibrio parahaemolyticus].	29.45	343	236	5	244	581	5	346	8e-35	146
rs:WP_042797823	hypothetical protein [Achromobacter xylosoxidans].	25.00	552	354	16	83	583	125	667	8e-35	150
rs:WP_010731590	DNA topoisomerase III, partial [Enterococcus faecalis].	27.01	411	263	9	293	675	88	489	9e-35	148
rs:WP_031841774	hypothetical protein [Vibrio parahaemolyticus].	29.23	349	206	10	3	321	4	341	9e-35	146
rs:WP_002338426	hypothetical protein, partial [Enterococcus faecium].	34.51	339	188	11	3	317	4	332	9e-35	145
tr:D9ZB73_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.23	648	398	25	3	612	4	609	9e-35	150
tr:U6FEN0_LACHE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.98	404	261	9	200	581	1	392	1e-34	148
rs:WP_013413259	DNA topoisomerase I [Methanothermus fervidus].	30.02	513	281	21	90	573	94	557	1e-34	150
tr:C3HSH8_BACTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.17	449	301	11	244	675	13	452	1e-34	150
rs:WP_004818409	DNA topoisomerase, partial [Anaerococcus hydrogenalis].	33.54	328	190	9	273	590	63	372	1e-34	145
tr:R3K3Y6_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.16	405	258	9	299	675	2	397	1e-34	146
rs:WP_002331394	hypothetical protein [Enterococcus faecalis].	27.16	405	258	9	299	675	2	397	1e-34	146
rs:WP_031604130	DNA topoisomerase III, partial [Salmonella enterica].	31.62	291	188	7	298	581	5	291	1e-34	144
tr:T0U6H2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.46	548	361	15	1	515	209	747	1e-34	150
rs:WP_043307593	DNA topoisomerase III [Burkholderia glumae].	25.67	413	271	10	256	634	300	710	1e-34	150
rs:WP_043307593	DNA topoisomerase III [Burkholderia glumae].	33.33	204	128	3	29	225	15	217	5e-25	120
rs:WP_000259048	DNA topoisomerase III [Streptococcus agalactiae].	26.92	572	347	20	36	578	39	568	1e-34	148
rs:WP_042685532	DNA topoisomerase I [Methermicoccus shengliensis].	26.52	660	412	29	1	630	1	617	1e-34	150
tr:C5A9D2_BURGB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.67	413	271	10	256	634	310	720	2e-34	150
tr:C5A9D2_BURGB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.62	232	142	4	1	225	1	227	9e-28	129
tr:T0ZCB8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD42728.1};	25.46	703	411	22	2	638	3	658	2e-34	150
tr:R7TCT6_CAPTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	27.64	445	277	12	108	514	2	439	2e-34	146
rs:WP_042101431	DNA topoisomerase III, partial [Escherichia coli].	30.90	301	197	7	288	581	1	297	2e-34	144
tr:W7B1H7_9LIST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.99	393	265	9	299	675	2	392	2e-34	145
tr:J6U692_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.12	490	310	13	186	639	18	491	2e-34	147
rs:WP_021632670	DNA topoisomerase, partial [Clostridium sp. ATCC BAA-442].	28.53	375	243	6	271	627	3	370	2e-34	146
rs:WP_040759096	DNA topoisomerase III, partial [Sporosarcina newyorkensis].	29.94	324	215	6	3	315	5	327	2e-34	144
rs:WP_033615686	DNA topoisomerase, partial [Enterococcus faecium].	27.01	411	263	9	293	675	84	485	2e-34	147
tr:A0A060HA84_XYLFS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.36	309	180	8	31	312	6	312	2e-34	143
tr:J9W7D3_LACBU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.36	402	262	9	200	581	1	392	3e-34	147
rs:WP_046831107	DNA topoisomerase III, partial [Xanthomonas axonopodis].	28.64	391	260	7	190	562	7	396	3e-34	145
tr:F9DSK4_9BACL	SubName: Full=DNA topoisomerase TopB {ECO:0000313|EMBL:EGQ26216.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EGQ26216.1};	29.94	324	215	6	3	315	5	327	3e-34	144
tr:K1UJH0_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC78335.1}; Flags: Fragment;	33.07	257	154	6	34	283	1	246	3e-34	143
rs:WP_039022797	DNA topoisomerase III, partial [Escherichia coli].	30.34	445	279	11	247	668	13	449	3e-34	146
rs:WP_032340913	DNA topoisomerase III, partial [Escherichia coli].	30.06	469	286	12	247	681	10	470	3e-34	146
rs:WP_017771170	MULTISPECIES: DNA topoisomerase III [Streptococcus].	26.03	607	382	21	1	578	2	570	3e-34	147
rs:WP_033615842	DNA topoisomerase, partial [Enterococcus faecium].	26.76	411	264	9	293	675	84	485	3e-34	146
rs:WP_000259054	DNA topoisomerase III [Streptococcus agalactiae].	26.23	610	377	21	1	578	2	570	3e-34	147
rs:WP_026597778	DNA topoisomerase III [Methylocystis sp. LW5].	25.05	555	372	16	44	560	30	578	3e-34	149
tr:A0A0B5HW63_9ARCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.67	647	385	25	3	612	5	605	3e-34	149
tr:I2X3M9_ECOLX	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EII43599.1};	30.06	469	286	12	247	681	31	491	3e-34	146
rs:WP_025916648	DNA topoisomerase III, partial [Herminiimonas sp. CN].	28.64	440	266	14	264	675	44	463	4e-34	148
tr:A0A084IJ21_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.62	318	198	7	5	303	19	326	4e-34	143
rs:WP_021674956	toprim domain protein, partial [Peptostreptococcaceae bacterium oral taxon 113].	40.00	205	109	6	2	201	4	199	4e-34	139
rs:WP_045384455	DNA topoisomerase III, partial [Vibrio campbellii].	25.57	567	372	19	1	526	1	558	4e-34	147
rs:WP_005957513	DNA topoisomerase III [Fusobacterium necrophorum].	28.22	404	267	8	1	393	1	392	4e-34	149
rs:WP_002840064	toprim domain protein, partial [Finegoldia magna].	35.93	231	138	5	1	228	1	224	4e-34	140
rs:WP_033655545	DNA topoisomerase, partial [Enterococcus faecium].	26.75	501	329	11	3	475	4	494	4e-34	146
rs:WP_012901188	DNA topoisomerase I [Methanocella paludicola].	25.30	664	412	26	1	630	1	614	5e-34	148
rs:WP_017768091	DNA topoisomerase III [Streptococcus agalactiae].	26.23	610	377	21	1	578	2	570	5e-34	147
rs:WP_000259047	MULTISPECIES: DNA topoisomerase III [Streptococcus].	26.23	610	377	21	1	578	2	570	5e-34	147
tr:L9TE08_SALEN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.72	290	187	7	299	581	1	286	5e-34	142
rs:WP_027432286	hypothetical protein [Lachnospira multipara].	25.34	659	411	25	51	656	10	640	6e-34	149
rs:WP_031613730	DNA topoisomerase III, partial [Salmonella enterica].	31.62	291	188	7	298	581	7	293	6e-34	142
rs:WP_045719108	DNA topoisomerase III, partial [Salmonella enterica].	31.62	291	188	7	298	581	4	290	6e-34	142
rs:WP_002352683	toprim domain protein, partial [Enterococcus faecium].	30.63	333	208	8	3	317	4	331	7e-34	142
rs:WP_040744842	DNA topoisomerase III, partial [alpha proteobacterium BAL199].	24.03	595	410	15	22	581	7	594	7e-34	146
rs:WP_008642133	DNA topoisomerase III [Cupriavidus sp. HMR-1].	25.06	411	276	8	256	634	300	710	7e-34	148
rs:WP_008642133	DNA topoisomerase III [Cupriavidus sp. HMR-1].	33.33	204	128	3	29	225	15	217	4e-25	121
tr:A0A0B3AMV3_9ARCH	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KHO51615.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KHO51615.1};	26.39	648	384	24	3	607	6	603	7e-34	148
rs:WP_042692623	DNA topoisomerase III, partial [Azospirillum sp. B506].	26.06	564	360	18	44	560	4	557	8e-34	146
tr:K1US83_9ZZZZ	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EKC81125.1};	30.47	338	219	7	308	636	2	332	8e-34	143
rs:WP_032177407	DNA topoisomerase III, partial [Escherichia coli].	30.50	423	264	10	247	647	6	420	8e-34	144
rs:WP_029657249	MULTISPECIES: DNA topoisomerase, partial [Enterococcus].	34.83	333	183	11	3	311	4	326	9e-34	142
tr:L2P8Z6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.22	339	189	11	3	317	4	332	9e-34	143
rs:WP_033606624	DNA topoisomerase, partial [Enterococcus faecium].	34.22	339	189	11	3	317	4	332	9e-34	142
rs:WP_033629072	DNA topoisomerase, partial [Enterococcus faecium].	34.22	339	189	11	3	317	4	332	9e-34	142
rs:WP_012974496	DNA topoisomerase III [Azospirillum lipoferum].	26.00	577	357	20	44	560	30	596	1e-33	147
rs:WP_028641865	hypothetical protein [Novosphingobium acidiphilum].	23.58	598	391	20	54	615	7	574	1e-33	147
tr:R2NN65_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.22	339	189	11	3	317	4	332	1e-33	143
tr:A0A0B8QFV7_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.52	393	237	14	2	362	3	387	1e-33	143
tr:R2V5M3_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.41	398	232	13	3	372	4	388	1e-33	143
rs:WP_023846762	DNA topoisomerase I, partial [Porphyromonas gingivalis].	32.36	343	208	10	69	394	1	336	1e-33	142
rs:WP_024083914	DNA topoisomerase I [Sulfolobus acidocaldarius].	29.78	628	339	27	3	585	11	581	1e-33	146
rs:WP_031806817	DNA topoisomerase III, partial [Staphylococcus aureus].	31.63	332	209	9	157	480	15	336	2e-33	142
tr:D6BE65_FUSNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.90	405	271	10	2	393	4	400	2e-33	147
rs:WP_007789451	DNA topoisomerase III [Peptostreptococcus stomatis].	24.92	606	402	19	1	578	1	581	2e-33	147
rs:WP_040239386	DNA topoisomerase III, partial [Klebsiella pneumoniae].	27.51	527	339	17	76	562	10	533	2e-33	145
tr:X6T0G3_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.94	386	253	8	299	664	2	378	2e-33	142
rs:WP_031620761	DNA topoisomerase III, partial [Salmonella enterica].	31.43	280	181	7	299	571	1	276	2e-33	140
rs:WP_023038729	DNA topoisomerase III [Fusobacterium nucleatum].	27.90	405	271	10	2	393	4	400	2e-33	147
rs:WP_032991737	DNA topoisomerase III, partial [Cronobacter dublinensis].	33.47	239	150	5	347	581	1	234	2e-33	140
rs:WP_034054058	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	28.42	373	245	8	271	629	30	394	2e-33	143
rs:XP_001620777	hypothetical protein NEMVEDRAFT_v1g222712, partial [Nematostella vectensis].	35.42	240	134	6	1	230	1	229	2e-33	138
rs:WP_042080259	DNA topoisomerase III, partial [Escherichia coli].	31.27	291	189	7	298	581	4	290	2e-33	141
rs:WP_000259046	DNA topoisomerase III [Streptococcus agalactiae].	26.23	610	377	21	1	578	2	570	2e-33	145
rs:WP_009092353	DNA topoisomerase I subunit omega, partial [Elizabethkingia anophelis].	38.16	207	115	4	1	204	1	197	2e-33	139
rs:WP_037616756	DNA topoisomerase [Streptococcus sinensis].	26.03	607	382	21	1	578	2	570	2e-33	145
tr:F3HNM9_PSEYM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.41	374	241	9	271	629	11	376	2e-33	142
tr:E2XSJ7_PSEFL	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFQ63311.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFQ63311.1};	30.19	308	194	6	1	293	1	302	2e-33	140
rs:WP_020304534	DNA topoisomerase III, partial [Pseudomonas syringae].	27.19	445	293	10	265	684	63	501	3e-33	144
gpu:CP009695_23	DNA topoisomerase family protein [Bacillus anthracis]	37.85	214	116	5	3	204	4	212	3e-33	137
rs:WP_021844917	DNA topoisomerase [Blautia hydrogenotrophica CAG:147].	27.76	508	306	15	131	579	1	506	3e-33	144
rs:WP_029485677	DNA topoisomerase, partial [Enterococcus faecium].	27.25	411	262	9	293	675	70	471	3e-33	143
rs:WP_002823696	DNA topoisomerase [Oenococcus oeni].	26.63	413	273	9	200	592	1	403	3e-33	144
rs:WP_003610064	DNA topoisomerase III [Methylosinus trichosporium].	25.18	560	373	16	44	564	30	582	3e-33	146
rs:WP_022238218	DNA topoisomerase [Clostridium sp. CAG:343].	30.16	378	226	8	238	578	13	389	3e-33	142
rs:WP_013438822	DNA topoisomerase III [Edwardsiella tarda].	27.33	461	289	13	1	431	1	445	3e-33	144
rs:WP_044427394	DNA topoisomerase III [Skermanella aerolata].	24.66	584	386	18	22	560	6	580	3e-33	146
rs:WP_031368321	hypothetical protein, partial [Clostridium botulinum].	37.86	243	141	6	3	239	4	242	4e-33	138
rs:WP_000259051	DNA topoisomerase III [Streptococcus agalactiae].	25.57	610	381	19	1	578	2	570	4e-33	144
rs:WP_044067990	DNA topoisomerase III, partial [Escherichia coli].	31.27	291	189	7	298	581	8	294	4e-33	140
rs:WP_038880477	DNA topoisomerase III, partial [Vibrio jasicida].	25.18	568	373	18	1	526	1	558	4e-33	144
tr:A8TWU8_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	24.00	600	414	15	22	586	7	599	5e-33	146
tr:A8TU58_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	24.00	600	414	15	22	586	7	599	5e-33	146
rs:WP_041657828	hypothetical protein [Achromobacter xylosoxidans].	24.28	552	358	15	83	583	125	667	5e-33	145
tr:H3RLD1_PANSE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EHT97815.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EHT97815.1};	27.36	552	360	13	84	599	2	548	6e-33	143
tr:E3HYK0_ACHXA	SubName: Full=DNA topoisomerase III 3 {ECO:0000313|EMBL:ADP20154.1}; EC=5.99.1.2 {ECO:0000313|EMBL:ADP20154.1};	24.28	552	358	15	83	583	138	680	6e-33	145
tr:D4RDK3_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.36	440	287	10	256	667	63	493	6e-33	143
tr:H3KHJ1_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	27.91	412	265	13	283	677	2	398	7e-33	143
tr:E4LJS6_9FIRM	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EFR40763.1};	32.00	250	157	5	3	244	24	268	7e-33	139
rs:WP_041269879	DNA topoisomerase III, partial [Geobacillus sp. WCH70].	37.45	235	132	7	1	224	1	231	7e-33	139
rs:WP_017643397	DNA topoisomerase III [Streptococcus agalactiae].	26.23	610	377	21	1	578	2	570	8e-33	143
rs:WP_034014014	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	28.50	379	241	10	272	629	1	370	8e-33	140
rs:WP_031623077	DNA topoisomerase III, partial [Salmonella enterica].	28.89	450	289	10	247	673	1	442	8e-33	142
rs:WP_023171016	DNA topoisomerase III, partial [Salmonella enterica].	28.89	450	289	10	247	673	2	443	8e-33	142
rs:WP_047090595	DNA topoisomerase III, partial [Escherichia coli].	28.74	435	270	13	1	409	1	421	1e-32	141
tr:W6N420_CLOTY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.34	543	364	16	157	679	13	539	1e-32	144
gp:CP008854_359	DNA topoisomerase III [Bacillus anthracis]	36.97	238	133	9	3	234	5	231	1e-32	137
sp:TOP1_METJA	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	27.11	712	412	25	3	668	8	658	1e-32	144
rs:WP_027281816	DNA topoisomerase III [Roseomonas gilardii].	25.00	564	363	17	44	560	31	581	1e-32	144
rs:WP_000259050	DNA topoisomerase III [Streptococcus agalactiae].	26.80	571	351	20	36	578	39	570	1e-32	143
rs:WP_034054055	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	27.55	392	258	9	256	629	15	398	1e-32	140
rs:WP_044405324	DNA topoisomerase III [Rhodopseudomonas palustris].	25.14	537	364	11	82	587	71	600	1e-32	144
rs:WP_000259049	DNA topoisomerase III [Streptococcus agalactiae].	26.80	571	351	20	36	578	39	570	1e-32	142
rs:WP_042037109	DNA topoisomerase III, partial [Escherichia coli].	29.25	424	269	9	247	647	35	450	1e-32	141
rs:WP_033628386	DNA topoisomerase, partial [Enterococcus faecalis].	28.85	416	255	12	154	541	20	422	2e-32	140
rs:WP_017262381	hypothetical protein [Lactobacillus rossiae].	27.04	636	389	22	41	630	48	654	2e-32	144
rs:WP_038530696	DNA topoisomerase III [Azospirillum brasilense].	24.92	590	385	16	22	564	6	584	2e-32	144
rs:WP_040220752	DNA topoisomerase III, partial [Klebsiella pneumoniae].	27.98	436	288	9	30	442	2	434	2e-32	140
rs:WP_031915409	DNA topoisomerase III, partial [Staphylococcus aureus].	33.89	298	179	9	3	294	4	289	2e-32	137
rs:WP_032583440	DNA topoisomerase I, partial [Bacteroides fragilis].	32.19	292	179	6	1	280	2	286	2e-32	137
rs:WP_039695713	DNA topoisomerase [Streptococcus gallolyticus].	25.80	562	360	17	40	578	43	570	2e-32	142
rs:WP_024882202	DNA topoisomerase III [Methylosinus sp. LW3].	25.49	561	372	18	44	564	30	584	2e-32	143
rs:WP_042688348	hypothetical protein [Candidatus Glomeribacter gigasporarum].	29.24	383	235	12	40	391	22	399	2e-32	140
tr:K1V4E7_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC78766.1}; Flags: Fragment;	33.73	249	147	7	30	271	1	238	2e-32	135
rs:WP_032825010	topoisomerase I, partial [Oenococcus oeni].	26.87	402	264	9	200	581	1	392	2e-32	140
rs:WP_015283225	DNA topoisomerase I, archaeal [Aciduliprofundum sp. MAR08-339].	24.22	669	413	23	3	636	4	613	2e-32	143
tr:A0A061P6L2_9BACL	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAK11904.1};	37.77	233	128	5	3	223	4	231	3e-32	136
tr:A0A0B5HKC5_9ARCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.28	647	393	21	1	612	2	599	3e-32	143
rs:WP_033872237	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	27.62	391	258	9	256	629	32	414	3e-32	140
rs:WP_011843614	DNA topoisomerase I [Methanoculleus marisnigri].	25.53	666	410	29	1	629	1	617	3e-32	144
rs:WP_008799769	DNA topoisomerase III [Fusobacterium nucleatum].	27.90	405	271	10	2	393	4	400	3e-32	144
tr:T1DTV0_9PORP	SubName: Full=DNA topoisomerase III, Bacteroidales-type {ECO:0000313|EMBL:GAD06024.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAD06024.1};	28.61	395	260	10	54	432	2	390	3e-32	140
rs:WP_038012980	DNA topoisomerase III, partial [Terasakiella pusilla].	26.32	608	385	22	22	581	6	598	3e-32	142
rs:WP_040600277	hypothetical protein, partial [Sphingobium ummariense].	25.00	628	386	19	3	581	4	595	3e-32	142
rs:WP_041811868	DNA topoisomerase III [Azospirillum brasilense].	24.55	607	400	16	22	581	6	601	3e-32	143
rs:WP_044546116	DNA topoisomerase I, partial [Parabacteroides distasonis].	27.59	406	267	12	1	390	1	395	3e-32	139
tr:T0IXR4_9SPHN	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	25.00	628	386	19	3	581	4	595	3e-32	142
rs:WP_031883560	DNA topoisomerase III, partial [Staphylococcus aureus].	33.44	299	181	9	3	295	4	290	4e-32	136
tr:G8AN84_AZOBR	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	24.55	607	400	16	22	581	9	604	4e-32	143
rs:WP_033874157	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	27.62	391	258	9	256	629	33	415	4e-32	139
tr:E2ZN59_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.29	464	281	14	242	673	1	435	4e-32	139
rs:WP_002351490	hypothetical protein [Streptococcus mutans].	25.91	606	384	21	1	578	2	570	4e-32	141
tr:C3DEJ6_BACTS	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EEM43623.1};	37.61	226	125	8	3	222	5	220	4e-32	135
rs:WP_031834529	DNA topoisomerase III, partial [Staphylococcus aureus].	27.54	443	297	9	190	620	1	431	4e-32	140
rs:WP_031859981	DNA topoisomerase III, partial [Staphylococcus aureus].	33.74	329	189	11	3	310	4	324	4e-32	137
tr:F0NX69_LACHH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.83	410	280	9	198	592	1	405	4e-32	140
rs:WP_023992619	DNA topoisomerase 1 [Methanobacterium sp. MB1].	25.94	690	371	28	3	629	4	616	4e-32	142
rs:WP_003524694	hypothetical protein, partial [[Clostridium] clostridioforme].	28.02	439	280	14	257	671	3	429	5e-32	139
rs:WP_035960666	hypothetical protein, partial [Fusobacterium ulcerans].	27.87	592	379	18	110	680	1	565	5e-32	141
rs:WP_031786154	DNA topoisomerase III, partial [Staphylococcus aureus].	34.43	273	156	7	3	270	4	258	5e-32	135
rs:WP_044145861	DNA topoisomerase, partial [Enterococcus faecium].	26.46	446	291	10	250	667	47	483	5e-32	140
rs:WP_018375466	DNA topoisomerase [Streptococcus orisratti].	25.45	605	388	20	1	578	2	570	6e-32	141
rs:WP_031910262	DNA topoisomerase III, partial [Staphylococcus aureus].	34.43	273	156	7	3	270	4	258	6e-32	135
rs:WP_044444103	DNA topoisomerase I [Bacillus mycoides].	25.15	684	391	22	3	655	5	598	6e-32	142
rs:WP_033604845	DNA topoisomerase, partial [Enterococcus faecalis].	27.99	343	227	6	352	675	44	385	7e-32	138
rs:WP_039671403	DNA topoisomerase [Streptococcus macedonicus].	25.98	562	359	18	40	578	43	570	8e-32	140
rs:WP_032882988	DNA topoisomerase, partial [Fusobacterium nucleatum].	26.74	576	360	21	100	635	2	555	8e-32	140
rs:WP_036247157	DNA topoisomerase, partial [Methylobacter sp. BBA5.1].	32.62	282	180	7	266	537	17	298	8e-32	135
tr:H1PYH8_9FUSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.05	574	368	17	125	680	13	559	9e-32	140
rs:WP_003526250	hypothetical protein, partial [[Clostridium] clostridioforme].	27.15	442	290	12	257	676	2	433	9e-32	139
rs:WP_004409943	DNA topoisomerase [Bacillus thuringiensis].	29.03	341	214	6	1	320	1	334	9e-32	137
rs:WP_024623473	DNA topoisomerase, partial [Streptococcus pyogenes].	31.22	394	234	10	198	580	1	368	9e-32	137
rs:WP_038821515	DNA topoisomerase III, partial [Pseudomonas syringae].	29.74	306	188	6	41	325	3	302	1e-31	136
rs:WP_016119511	hypothetical protein, partial [Bacillus cereus].	29.33	416	266	12	3	399	5	411	1e-31	139
rs:WP_001241571	hypothetical protein, partial [Salmonella enterica].	32.41	216	134	5	1	210	1	210	1e-31	133
rs:WP_022490063	DNA topoisomerase [Clostridium sp. CAG:567].	27.02	470	274	13	170	578	1	462	1e-31	139
rs:WP_002825272	TraA family conjugation nicking enzyme, partial [Oenococcus oeni].	26.37	402	266	9	200	581	1	392	1e-31	139
rs:WP_025481759	DNA topoisomerase [Enterococcus faecium].	26.19	485	321	12	219	680	1	471	1e-31	139
rs:WP_027973723	DNA topoisomerase [Streptococcus porci].	25.45	605	388	20	1	578	2	570	1e-31	140
tr:F3J5T5_PSEAP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	29.36	327	199	8	84	385	8	327	1e-31	136
rs:WP_040175367	hypothetical protein, partial [Phaeobacter sp. S26].	24.75	610	394	19	3	574	6	588	1e-31	141
tr:J3HUJ6_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.98	441	288	12	264	680	13	443	2e-31	140
rs:WP_028168975	DNA topoisomerase III [Bradyrhizobium elkanii].	24.53	534	359	13	82	581	71	594	2e-31	141
rs:WP_040501928	DNA topoisomerase III, partial [Herbaspirillum sp. YR522].	26.98	441	288	12	264	680	13	443	2e-31	140
rs:WP_033500972	DNA topoisomerase III, partial [Bifidobacterium kashiwanohense].	25.49	463	273	13	277	679	1	451	2e-31	138
rs:WP_012955193	DNA topoisomerase I [Methanobrevibacter ruminantium].	27.81	543	333	21	87	607	88	593	2e-31	141
rs:WP_012308892	DNA topoisomerase I [Candidatus Korarchaeum cryptofilum].	25.15	680	417	26	3	638	4	635	2e-31	140
rs:WP_040765487	DNA topoisomerase III, partial [Sutterella parvirubra].	27.93	401	257	13	294	677	3	388	2e-31	139
tr:T1BI43_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD53810.1}; Flags: Fragment;	27.48	302	208	6	32	325	86	384	2e-31	136
tr:S4NK75_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.24	340	214	8	261	585	18	342	2e-31	135
rs:WP_014248119	DNA topoisomerase III [Azospirillum lipoferum].	25.42	590	381	19	22	560	6	587	2e-31	140
rs:WP_017650048	DNA topoisomerase [Streptococcus agalactiae].	25.22	571	360	18	36	578	39	570	2e-31	139
rs:WP_047201597	DNA topoisomerase [Streptococcus agalactiae].	25.74	571	357	19	36	578	39	570	2e-31	139
rs:WP_011822082	DNA topoisomerase I [Hyperthermus butylicus].	24.47	662	412	23	3	630	15	622	2e-31	140
rs:WP_002261844	hypothetical protein [Streptococcus mutans].	25.95	605	385	21	1	578	2	570	2e-31	139
rs:WP_014343006	DNA topoisomerase III, partial [Klebsiella pneumoniae].	33.75	240	148	6	347	581	6	239	3e-31	134
rs:WP_004030988	DNA topoisomerase I [Methanobacterium formicicum].	26.67	600	331	22	82	631	78	618	3e-31	140
tr:W4LEV6_9DELT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETW96235.1}; Flags: Fragment;	30.99	342	218	8	351	676	1	340	3e-31	137
tr:A0A069D2D9_9LACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.40	489	312	16	218	673	21	499	3e-31	138
rs:WP_045582666	DNA topoisomerase III [Azospirillum thiophilum].	24.09	602	386	18	22	560	6	599	3e-31	140
tr:A0A075MM36_9ARCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.43	645	410	21	3	610	6	616	3e-31	140
rs:WP_001235858	hypothetical protein, partial [Salmonella enterica].	32.55	298	169	12	1	273	1	291	3e-31	134
rs:WP_043834996	DNA topoisomerase III [Roseomonas aerilata].	24.55	554	370	16	44	560	31	573	3e-31	140
rs:WP_020199469	hypothetical protein [Sulfolobales archaeon Acd1].	24.71	607	371	19	38	610	50	604	3e-31	139
rs:WP_016504476	DNA topoisomerase III, partial [Pasteurella multocida].	36.13	238	127	8	1	223	1	228	3e-31	133
rs:WP_044954273	DNA topoisomerase III, partial [Faecalibacterium prausnitzii].	26.03	461	280	14	245	673	1	432	3e-31	137
rs:WP_033500581	DNA topoisomerase III, partial [Bifidobacterium kashiwanohense].	34.89	235	140	8	1	228	1	229	3e-31	134
rs:WP_035674877	DNA topoisomerase III, partial [Azospirillum brasilense].	24.70	583	389	16	22	564	6	578	4e-31	139
rs:WP_027424619	DNA topoisomerase I [Lachnospiraceae bacterium AC3007].	25.56	626	379	24	90	675	67	645	4e-31	139
rs:WP_011278207	DNA topoisomerase I [Sulfolobus acidocaldarius].	29.48	631	337	27	3	585	11	581	4e-31	139
rs:WP_033502000	DNA topoisomerase III, partial [Bifidobacterium kashiwanohense].	30.66	287	181	9	1	280	1	276	4e-31	133
tr:A0A0B3AAN5_9ARCH	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KHO49463.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KHO49463.1};	26.34	558	338	21	85	610	10	526	5e-31	139
rs:WP_024635937	DNA topoisomerase [Enterococcus faecium].	26.76	482	322	11	219	680	1	471	6e-31	136
tr:A0A084IJ20_9GAMM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KEZ76704.1};	28.12	313	216	5	308	614	2	311	6e-31	134
rs:WP_014620285	DNA topoisomerase III [Streptococcus gallolyticus].	25.18	568	356	17	40	578	43	570	6e-31	137
rs:WP_003045929	hypothetical protein [Streptococcus canis].	24.78	569	365	17	36	578	39	570	7e-31	137
rs:WP_012194426	DNA topoisomerase I [Methanococcus maripaludis].	26.80	679	407	30	3	640	4	633	7e-31	139
rs:WP_002330416	hypothetical protein [Enterococcus faecium].	26.20	481	326	10	219	680	1	471	7e-31	136
rs:WP_033655636	DNA topoisomerase, partial [Enterococcus faecium].	35.52	259	143	8	3	244	4	255	7e-31	133
tr:F3GHG4_PSESJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.53	361	231	9	286	629	2	352	8e-31	135
rs:WP_019485491	hypothetical protein, partial [Pseudomonas aeruginosa].	28.61	353	231	9	291	629	1	346	8e-31	134
tr:I6F131_SHIBO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.95	349	221	8	295	629	2	344	9e-31	134
rs:WP_032825761	topoisomerase I, partial [Oenococcus oeni].	27.16	335	220	6	261	581	9	333	9e-31	135
rs:WP_021632671	toprim domain protein, partial [Clostridium sp. ATCC BAA-442].	33.48	233	133	7	3	226	5	224	9e-31	132
rs:WP_030091797	hypothetical protein, partial [Sphingomonas sp. DC-6].	24.72	619	398	19	3	581	5	595	9e-31	138
rs:WP_002335445	hypothetical protein [Enterococcus faecalis].	35.52	259	143	8	3	244	4	255	1e-30	133
tr:V1UW93_SALET	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.28	304	185	8	1	284	1	294	1e-30	134
rs:WP_007315375	DNA topoisomerase I [Methanolinea tarda].	24.42	651	402	26	1	614	1	598	1e-30	139
rs:WP_009366453	DNA topoisomerase I [Halogranum salarium].	23.98	738	422	29	2	661	6	682	1e-30	139
rs:WP_043366110	DNA topoisomerase III, partial [Belnapia sp. F-4-1].	24.36	509	349	11	82	560	71	573	1e-30	137
rs:WP_013826367	DNA topoisomerase I [Methanobacterium paludis].	26.50	585	342	21	87	631	88	624	1e-30	138
rs:WP_025478727	DNA topoisomerase, partial [Enterococcus faecium].	27.39	471	304	11	3	445	4	464	1e-30	135
tr:G0QFA3_NANS0	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.56	622	382	22	3	588	5	581	1e-30	138
rs:WP_018377913	DNA topoisomerase III [Streptococcus ovis].	25.70	572	356	20	36	578	39	570	1e-30	137
rs:WP_029645004	MULTISPECIES: DNA topoisomerase, partial [Enterococcus].	35.09	285	154	10	3	263	4	281	1e-30	132
rs:WP_031892024	DNA topoisomerase III, partial [Staphylococcus aureus].	35.56	239	140	6	3	236	4	233	1e-30	130
rs:WP_044656926	DNA topoisomerase I, partial [Bacteroides acidifaciens].	34.88	215	122	5	1	204	1	208	2e-30	130
rs:WP_020916758	DNA topoisomerase III [Streptococcus lutetiensis].	25.58	559	357	18	44	578	47	570	2e-30	136
tr:V5EIH7_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.74	404	266	9	200	581	1	392	2e-30	135
rs:WP_036279667	DNA topoisomerase III [Methylocystis sp. ATCC 49242].	25.44	562	369	17	44	564	30	582	2e-30	138
rs:WP_031921358	DNA topoisomerase III, partial [Staphylococcus aureus].	35.56	239	140	6	3	236	4	233	2e-30	130
rs:WP_036857940	DNA topoisomerase I, partial [Prevotella amnii].	36.79	212	115	6	4	204	5	208	2e-30	129
tr:R3T638_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.39	471	304	11	3	445	5	465	2e-30	135
rs:WP_031921871	DNA topoisomerase III, partial [Staphylococcus aureus].	35.56	239	140	6	3	236	4	233	2e-30	130
tr:L2J129_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELA74246.1};	35.09	285	154	10	3	263	4	281	2e-30	132
rs:WP_008802992	DNA topoisomerase III [Fusobacterium nucleatum].	24.55	672	433	20	2	627	4	647	2e-30	138
rs:WP_031806809	DNA topoisomerase III, partial [Staphylococcus aureus].	35.56	239	140	6	3	236	4	233	2e-30	130
tr:R2AW14_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.39	471	304	11	3	445	5	465	2e-30	135
rs:WP_042751142	topoisomerase I, partial [Lactobacillus brevis].	27.90	319	206	6	277	581	1	309	2e-30	134
rs:WP_031786349	DNA topoisomerase III, partial [Staphylococcus aureus].	28.25	400	272	6	188	580	13	404	2e-30	134
rs:WP_034428120	DNA topoisomerase, partial [Anaerococcus pacaensis].	34.42	308	172	10	294	590	1	289	2e-30	131
rs:WP_034951136	DNA topoisomerase III, partial [Erwinia oleae].	29.49	312	205	4	307	610	2	306	2e-30	133
rs:WP_019777165	hypothetical protein [Streptococcus sobrinus].	26.19	565	346	18	46	580	49	572	2e-30	136
rs:WP_033627502	DNA topoisomerase, partial [Enterococcus faecium].	26.60	406	261	10	290	667	17	413	2e-30	134
tr:E3EPR9_BIFBS	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ADO52606.1};	31.31	297	186	11	2	288	3	291	2e-30	133
rs:WP_012617952	DNA topoisomerase I [Methanosphaerula palustris].	25.57	653	392	28	1	614	1	598	2e-30	138
rs:WP_024725066	hypothetical protein, partial [Clostridiales bacterium VE202-03].	33.48	233	133	7	3	226	5	224	2e-30	130
rs:WP_032838476	DNA topoisomerase I [Fusobacterium sp. CM1].	24.55	672	433	20	2	627	4	647	2e-30	137
rs:WP_015590146	DNA topoisomerase I [Archaeoglobus sulfaticallidus].	25.27	740	417	30	3	682	6	669	3e-30	137
tr:U2DT69_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.16	292	182	6	1	280	1	285	3e-30	132
rs:WP_019192864	hypothetical protein, partial [Anaerococcus pacaensis].	32.57	307	179	10	294	590	1	289	3e-30	131
rs:WP_002409429	toprim domain protein, partial [Enterococcus faecalis].	35.52	259	143	8	3	244	4	255	3e-30	130
rs:WP_017648495	DNA topoisomerase [Streptococcus agalactiae].	25.86	607	383	21	1	578	2	570	3e-30	135
rs:WP_022176407	DNA topoisomerase [Firmicutes bacterium CAG:552].	27.50	629	366	25	84	666	56	640	3e-30	137
rs:WP_014726311	DNA topoisomerase [Burkholderia sp. KJ006].	23.51	689	427	29	2	620	3	661	4e-30	137
rs:WP_031794621	DNA topoisomerase III, partial [Staphylococcus aureus].	36.17	235	136	6	3	232	4	229	4e-30	129
rs:WP_016317479	DNA topoisomerase III, partial [Anaerotruncus sp. G3(2012)].	29.21	380	240	11	195	557	2	369	4e-30	132
rs:WP_009905893	DNA topoisomerase [Peptoclostridium difficile].	25.08	626	377	23	124	678	4	608	4e-30	135
rs:WP_026172433	hypothetical protein, partial [euryarchaeote SCGC AAA261-G15].	25.27	637	405	25	4	616	1	590	4e-30	136
rs:WP_009683128	DNA topoisomerase III, partial [Pseudomonas sp. TJI-51].	28.34	314	214	6	278	581	1	313	4e-30	132
rs:WP_023040405	DNA topoisomerase III [Fusobacterium nucleatum].	24.55	672	433	20	2	627	4	647	4e-30	137
rs:WP_009643973	DNA topoisomerase, partial [Mogibacterium sp. CM50].	30.40	329	208	5	265	587	4	317	4e-30	131
rs:WP_032242256	DNA topoisomerase III, partial [Escherichia coli].	28.75	400	259	9	1	381	1	393	4e-30	133
tr:T0CMX4_CLOSO	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EPZ55487.1};	34.88	258	141	8	1	243	1	246	5e-30	130
rs:WP_042713119	DNA topoisomerase III, partial [Klebsiella cf. planticola B43].	30.08	266	175	5	346	606	2	261	5e-30	130
rs:WP_010726672	hypothetical protein, partial [Enterococcus faecium].	26.64	593	384	17	118	687	7	571	5e-30	136
rs:WP_002351371	toprim domain protein, partial [Enterococcus faecium].	36.08	255	147	8	3	244	4	255	5e-30	130
rs:WP_037619942	DNA topoisomerase, partial [Streptococcus parauberis].	35.52	259	143	8	3	244	4	255	5e-30	129
rs:WP_019781775	hypothetical protein [Streptococcus sobrinus].	26.19	565	346	19	46	580	49	572	5e-30	135
rs:WP_002819867	hypothetical protein [Oenococcus oeni].	26.37	402	266	9	200	581	1	392	5e-30	134
rs:WP_040077835	DNA topoisomerase III, partial [Escherichia coli].	28.75	327	196	10	1	307	1	310	6e-30	130
rs:WP_039107348	hypothetical protein [Lactobacillus brevis].	24.69	721	463	31	3	680	4	687	6e-30	136
rs:WP_033646108	hypothetical protein [Bacillus anthracis].	29.29	396	243	12	276	647	4	386	6e-30	132
rs:WP_046308328	hypothetical protein [Lactobacillus apis].	24.49	735	486	25	3	678	4	728	6e-30	136
rs:WP_008624637	toprim domain protein, partial [Paraprevotella xylaniphila].	36.74	215	118	4	1	204	1	208	6e-30	128
rs:WP_002314343	DNA topoisomerase [Enterococcus faecium].	25.99	481	327	10	219	680	1	471	6e-30	134
rs:WP_029750153	DNA topoisomerase, partial [Streptococcus agalactiae].	31.10	344	214	6	251	587	27	354	6e-30	132
rs:WP_031875871	DNA topoisomerase III, partial [Staphylococcus aureus].	32.50	280	161	5	346	615	13	274	7e-30	132
rs:WP_014868235	DNA topoisomerase I [Methanoculleus bourgensis].	23.11	662	433	20	1	630	1	618	7e-30	136
rs:WP_033405780	hypothetical protein, partial [Kiloniella laminariae].	25.83	604	376	20	22	560	6	602	7e-30	135
rs:WP_019484713	hypothetical protein, partial [Pseudomonas aeruginosa].	27.93	358	229	9	291	630	1	347	7e-30	132
rs:WP_003171354	DNA topoisomerase III [Bacillus anthracis].	29.29	396	243	12	276	647	4	386	7e-30	132
rs:WP_031653318	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	27.79	367	235	10	284	629	1	358	7e-30	132
rs:WP_042513650	hypothetical protein [Bacillus anthracis].	29.63	378	229	12	276	629	4	368	7e-30	132
tr:V2LGS5_SALET	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESJ51281.1};	30.34	267	178	5	346	608	6	268	8e-30	130
tr:K1SBE4_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC44731.1}; Flags: Fragment;	36.74	215	118	4	1	204	1	208	8e-30	128
rs:WP_011868545	DNA topoisomerase I [Methanococcus maripaludis].	27.06	680	404	30	3	640	4	633	8e-30	136
rs:WP_000259052	hypothetical protein [Streptococcus agalactiae].	25.42	602	392	23	1	578	2	570	8e-30	134
tr:R2W3D4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.91	472	305	11	3	445	5	465	8e-30	133
rs:WP_019778497	hypothetical protein [Streptococcus sobrinus].	26.27	571	350	19	46	586	49	578	8e-30	134
rs:WP_008389044	DNA topoisomerase I [Halosarcina pallida].	23.13	722	437	28	2	661	6	671	8e-30	136
rs:WP_014406775	DNA topoisomerase I [Methanocella conradii].	25.83	662	411	27	1	630	1	614	8e-30	135
rs:WP_045152427	DNA topoisomerase III, partial [Escherichia coli].	28.64	412	258	17	1	385	1	403	8e-30	132
tr:A0A090JUA7_METFO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.32	538	300	18	82	581	78	562	9e-30	135
rs:WP_024526862	hypothetical protein [Lactobacillus brevis].	24.34	641	421	25	3	612	4	611	9e-30	135
rs:WP_034951167	DNA topoisomerase III, partial [Erwinia oleae].	28.85	312	207	4	307	610	4	308	9e-30	131
rs:WP_024052236	DNA topoisomerase [Streptococcus anginosus].	25.22	567	361	19	40	580	43	572	9e-30	134
rs:WP_023916854	DNA topoisomerase III [Streptococcus sanguinis].	24.33	563	375	16	36	578	39	570	1e-29	134
rs:WP_037450141	DNA topoisomerase III [Skermanella stibiiresistens].	24.50	604	404	19	22	581	6	601	1e-29	135
gp:CP002165_2004	DNA topoisomerase [Xylella fastidiosa subsp. fastidiosa GB514]	33.96	268	158	7	61	312	26	290	1e-29	130
rs:WP_033614632	DNA topoisomerase, partial [Enterococcus faecium].	26.89	357	232	8	293	629	84	431	1e-29	132
rs:WP_032443669	DNA topoisomerase III, partial [Klebsiella pneumoniae].	29.29	437	266	11	279	680	3	431	1e-29	132
rs:WP_046502101	DNA topoisomerase III, partial [Kiloniella sp. P1-1].	26.22	576	364	23	36	560	21	586	1e-29	135
rs:WP_009880163	DNA topoisomerase III [Bacillus anthracis].	29.29	396	243	12	276	647	4	386	1e-29	131
rs:WP_044477088	DNA topoisomerase III, partial [Oceanobacillus massiliensis].	39.80	201	110	5	3	194	5	203	1e-29	127
rs:WP_010722281	DNA topoisomerase III, partial [Enterococcus faecium].	26.89	357	232	8	293	629	84	431	1e-29	132
rs:WP_032566601	DNA topoisomerase I, partial [Bacteroides fragilis].	36.74	215	118	4	1	204	1	208	1e-29	129
rs:WP_046835606	DNA topoisomerase III, partial [Pseudomonas amygdali].	27.50	360	237	8	200	537	4	361	1e-29	131
rs:WP_031859570	DNA topoisomerase III, partial [Staphylococcus aureus].	36.21	232	134	6	3	229	4	226	1e-29	127
tr:J9GH34_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJX06329.1}; Flags: Fragment;	35.71	238	144	5	90	325	1	231	1e-29	128
rs:WP_029645005	MULTISPECIES: DNA topoisomerase, partial [Lactobacillales].	26.76	355	231	8	295	629	1	346	1e-29	130
rs:WP_011170900	DNA topoisomerase I [Methanococcus maripaludis].	27.03	677	408	28	3	640	4	633	1e-29	135
tr:M1JAI4_PHODP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.10	498	336	16	1	472	1	487	1e-29	132
rs:WP_036887905	DNA topoisomerase I, partial [Prevotella maculosa].	37.61	218	115	7	4	210	5	212	1e-29	129
rs:WP_011976610	DNA topoisomerase I [Methanococcus maripaludis].	26.73	681	405	28	3	640	4	633	1e-29	135
rs:WP_013999415	DNA topoisomerase I [Methanococcus maripaludis].	27.03	677	408	28	3	640	4	633	2e-29	135
rs:WP_047213735	DNA topoisomerase III, partial [Staphylococcus aureus].	32.50	280	161	5	346	615	32	293	2e-29	131
tr:S4E3Z4_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EPI14111.1};	36.32	234	127	7	3	221	4	230	2e-29	128
rs:WP_001840612	DNA topoisomerase III, partial [Salmonella enterica].	32.22	239	155	4	346	581	32	266	2e-29	129
rs:WP_044180300	DNA topoisomerase III, partial [Photobacterium damselae].	25.25	495	333	16	1	469	1	484	2e-29	132
rs:WP_031610507	DNA topoisomerase III, partial [Salmonella enterica].	31.30	393	239	11	294	663	3	387	2e-29	131
rs:WP_042707682	DNA topoisomerase I [Methanobrevibacter wolinii].	26.44	537	321	16	82	588	79	571	2e-29	135
rs:WP_016627781	DNA topoisomerase [Enterococcus faecium].	25.57	485	324	11	219	680	1	471	2e-29	132
rs:WP_037622473	DNA topoisomerase [Streptococcus sp. 2_1_36FAA].	24.16	563	376	16	36	578	39	570	2e-29	133
rs:WP_029658009	DNA topoisomerase, partial [Enterococcus faecalis].	33.02	324	189	11	1	303	4	320	2e-29	129
rs:WP_047210003	DNA topoisomerase [Streptococcus agalactiae].	26.00	573	345	19	40	578	43	570	2e-29	133
rs:WP_004591511	DNA topoisomerase I [Haloarcula japonica].	24.34	719	432	29	1	661	1	665	2e-29	135
rs:WP_002409753	toprim domain protein, partial [Enterococcus faecalis].	35.14	259	144	8	3	244	4	255	2e-29	128
tr:E2CSK1_9RHOB	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	24.60	626	393	18	3	581	4	597	2e-29	134
rs:WP_003030107	DNA topoisomerase [Streptococcus anginosus].	25.04	567	362	19	40	580	43	572	2e-29	133
tr:R2NN74_9ENTE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOH73452.1};	36.32	234	127	7	3	221	4	230	2e-29	128
rs:WP_035023683	DNA topoisomerase, partial [Enterococcus villorum].	26.61	357	233	8	293	629	84	431	2e-29	131
tr:R2S4C9_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.61	357	233	8	293	629	89	436	2e-29	131
rs:WP_032820832	topoisomerase I, partial [Oenococcus oeni].	26.87	335	221	6	261	581	9	333	2e-29	131
tr:D4ELA0_ENTFL	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EFE19574.1};	36.36	231	125	7	3	218	4	227	2e-29	127
rs:WP_000259055	DNA topoisomerase III [Streptococcus agalactiae].	25.48	577	351	19	36	578	39	570	2e-29	133
tr:D0RWS4_9STRE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	24.16	563	376	16	36	578	80	611	3e-29	133
rs:WP_006739580	DNA topoisomerase [Streptococcus urinalis].	26.37	565	355	21	40	579	43	571	3e-29	133
tr:A0A089ZH13_METFO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.32	538	300	18	82	581	78	562	3e-29	134
rs:WP_029656734	DNA topoisomerase, partial [Enterococcus faecalis].	32.92	322	188	11	3	303	4	318	3e-29	129
tr:V1URM1_SALET	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESG40303.1};	30.35	257	173	4	329	581	11	265	3e-29	128
rs:WP_010714235	hypothetical protein [Enterococcus faecalis].	32.92	322	188	11	3	303	4	318	3e-29	129
rs:WP_013683176	DNA topoisomerase I [Archaeoglobus veneficus].	25.37	678	406	28	3	639	4	622	3e-29	134
tr:T0L554_9NEIS	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	29.98	427	248	15	3	406	5	403	3e-29	130
tr:Z2EZT3_VIBPH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.94	255	146	5	161	390	31	285	3e-29	129
rs:WP_002418952	DNA topoisomerase, partial [Enterococcus faecalis].	29.59	338	216	8	349	671	25	355	3e-29	130
rs:WP_046735973	DNA topoisomerase III, partial [Xanthomonas axonopodis].	27.49	382	258	7	199	562	1	381	3e-29	130
rs:WP_032576955	DNA topoisomerase I, partial [Bacteroides fragilis].	25.70	463	314	11	41	480	2	457	4e-29	131
rs:WP_044423162	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	28.30	311	198	7	1	294	1	303	4e-29	128
rs:WP_019780742	hypothetical protein, partial [Streptococcus sobrinus].	26.02	565	347	19	46	580	23	546	4e-29	132
tr:A0A0B3AKA5_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.85	663	361	29	3	612	134	725	4e-29	134
rs:WP_031834942	MULTISPECIES: DNA topoisomerase, partial [Bacilli].	36.52	230	124	7	3	217	4	226	4e-29	126
rs:WP_040682411	DNA topoisomerase I, partial [Methanobrevibacter boviskoreani].	27.53	523	323	19	75	576	72	559	4e-29	133
rs:WP_036873431	DNA topoisomerase I, partial [Prevotella maculosa].	36.74	215	118	4	1	204	1	208	4e-29	126
tr:J9GR19_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJX04953.1};	29.36	344	193	13	349	652	41	374	4e-29	129
rs:WP_004577989	Topoisomerase IA, partial [nanoarchaeote Nst1].	28.39	546	303	24	3	515	2	492	4e-29	131
tr:A0A060HRZ8_9ARCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.23	654	407	20	3	612	4	619	4e-29	133
rs:WP_032495452	DNA topoisomerase, partial [Enterococcus thailandicus].	27.84	334	221	6	361	675	1	333	5e-29	129
tr:X2MHZ5_SALEN	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AHO12289.1};	36.24	229	125	9	1	215	1	222	5e-29	126
rs:WP_019792391	hypothetical protein [Streptococcus sobrinus].	26.08	579	341	20	46	586	49	578	5e-29	132
tr:A0A0B5GGX8_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.92	658	401	26	1	616	1	607	5e-29	134
rs:WP_044423261	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	28.30	311	198	7	1	294	1	303	5e-29	128
tr:L2L4T1_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.78	351	228	8	299	629	2	343	5e-29	129
rs:WP_016357804	DNA topoisomerase I TopA [Methanobrevibacter sp. AbM4].	26.94	605	362	23	3	576	4	559	6e-29	133
rs:WP_014040904	DNA topoisomerase I [Haloarcula hispanica].	24.92	658	401	26	1	616	1	607	6e-29	133
rs:WP_010715569	hypothetical protein [Enterococcus faecalis].	36.96	230	131	7	3	221	4	230	6e-29	126
rs:WP_023252663	DNA topoisomerase III, partial [Salmonella enterica].	36.24	229	125	9	1	215	1	222	6e-29	126
rs:WP_018153854	DNA topoisomerase I [Methanothermococcus thermolithotrophicus].	25.51	682	414	26	3	640	4	635	6e-29	133
rs:WP_045719125	DNA topoisomerase III, partial [Salmonella enterica].	36.24	229	125	9	1	215	1	222	7e-29	127
tr:K1V3R2_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC78506.1}; Flags: Fragment;	37.36	182	101	5	1	177	1	174	7e-29	124
gp:CP007335_1664	hypothetical protein [Salmonella enterica subsp. enterica serovar Enteritidis str.]	36.24	229	125	9	1	215	1	222	7e-29	126
rs:WP_029657371	DNA topoisomerase, partial [Enterococcus faecalis].	36.96	230	131	7	3	221	4	230	7e-29	126
rs:WP_001700602	DNA topoisomerase III, partial [Salmonella enterica].	36.24	229	125	9	1	215	1	222	7e-29	127
rs:WP_023195577	DNA topoisomerase III, partial [Salmonella enterica].	36.24	229	125	9	1	215	1	222	7e-29	127
rs:WP_042889025	DNA topoisomerase, partial [Enterococcus faecalis].	26.50	351	229	8	295	625	1	342	7e-29	128
rs:WP_014513937	DNA topoisomerase I [Sulfolobus islandicus].	25.32	620	370	24	3	580	11	579	7e-29	132
rs:WP_023250895	DNA topoisomerase III, partial [Salmonella enterica].	36.24	229	125	9	1	215	1	222	7e-29	127
rs:WP_001235857	hypothetical protein, partial [Salmonella enterica].	36.24	229	125	9	1	215	1	222	7e-29	126
rs:WP_023260902	DNA topoisomerase III, partial [Salmonella enterica].	36.24	229	125	9	1	215	1	222	7e-29	127
rs:WP_020365116	hypothetical protein, partial [Staphylococcus epidermidis].	38.73	204	111	7	3	201	4	198	7e-29	125
rs:WP_023251570	DNA topoisomerase III, partial [Salmonella enterica].	36.24	229	125	9	1	215	1	222	7e-29	126
rs:WP_044067989	DNA topoisomerase III, partial [Escherichia coli].	31.42	296	171	12	1	271	1	289	7e-29	127
rs:WP_013266347	DNA topoisomerase III [Acidilobus saccharovorans].	24.25	569	363	17	75	612	84	615	7e-29	132
rs:WP_002960235	DNA topoisomerase III [Streptococcus sobrinus].	25.97	566	346	18	46	580	49	572	8e-29	131
tr:Q1AUL7_RUBXD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.82	680	430	26	1	639	1	633	8e-29	132
tr:W7L256_XYLFS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.58	268	159	7	61	312	26	290	8e-29	127
rs:WP_008515661	DNA topoisomerase I, archaeal [Methanobacterium sp. Maddingley MBC34].	27.14	538	301	18	82	581	78	562	8e-29	132
rs:WP_017646907	DNA topoisomerase [Streptococcus agalactiae].	24.96	601	396	19	1	578	2	570	8e-29	131
rs:WP_001727616	DNA topoisomerase III, partial [Salmonella enterica].	36.24	229	125	9	1	215	1	222	9e-29	127
rs:WP_008582161	DNA topoisomerase I [Halorubrum hochstenium].	24.50	743	435	32	2	661	6	705	9e-29	133
rs:WP_025271724	DNA topoisomerase [Streptococcus anginosus].	24.78	565	364	18	40	579	43	571	9e-29	131
rs:WP_009683127	DNA topoisomerase III, partial [Pseudomonas sp. TJI-51].	31.98	247	139	7	1	233	1	232	9e-29	126
rs:WP_031653319	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	29.29	297	185	9	1	280	1	289	1e-28	127
tr:W1WYM7_9FIRM	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ETJ23046.1}; Flags: Fragment;	33.05	233	140	6	1	224	1	226	1e-28	126
rs:WP_041329053	hypothetical protein, partial [Rubrobacter xylanophilus].	23.82	680	430	26	1	639	1	633	1e-28	132
rs:WP_023198152	DNA topoisomerase III, partial [Salmonella enterica].	36.24	229	125	9	1	215	1	222	1e-28	125
rs:WP_012236045	ATP-dependent DNA helicase RecQ [Sorangium cellulosum].	33.19	226	141	5	1	223	1	219	1e-28	133
rs:WP_012236045	ATP-dependent DNA helicase RecQ [Sorangium cellulosum].	38.24	136	83	1	446	581	550	684	1e-14	88.6
rs:WP_012236045	ATP-dependent DNA helicase RecQ [Sorangium cellulosum].	33.86	127	78	3	271	392	328	453	3e-11	77.4
rs:WP_033629053	DNA topoisomerase, partial [Enterococcus faecium].	26.88	465	306	12	130	578	19	465	1e-28	131
rs:WP_001719610	DNA topoisomerase III, partial [Salmonella enterica].	28.87	388	250	9	1	369	1	381	1e-28	128
rs:WP_017650630	DNA topoisomerase [Streptococcus agalactiae].	24.96	601	396	19	1	578	2	570	1e-28	131
rs:WP_032331321	DNA topoisomerase III, partial [Escherichia coli].	31.93	238	155	4	347	581	16	249	1e-28	127
rs:WP_037612612	DNA topoisomerase [Streptococcus sp. OBRC6].	24.78	565	364	18	40	579	43	571	1e-28	130
tr:A0A0A7LFL8_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.81	665	414	25	2	629	3	618	1e-28	132
tr:A0A096CLF8_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGF46149.1}; Flags: Fragment;	28.20	383	232	11	309	673	15	372	2e-28	128
rs:WP_014512616	DNA topoisomerase I [Sulfolobus islandicus].	25.28	621	368	24	3	580	11	578	2e-28	131
rs:WP_036885046	hypothetical protein, partial [Prevotella disiens].	28.20	383	232	11	309	673	1	358	2e-28	128
rs:WP_011954063	DNA topoisomerase I [Methanobrevibacter smithii].	27.54	541	331	20	90	607	93	595	2e-28	131
rs:WP_032602805	DNA topoisomerase I, partial [Bacteroides fragilis].	33.09	272	161	7	1	259	1	264	2e-28	125
tr:D2U1Z5_9ENTR	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:CBA74913.1}; Flags: Fragment;	27.63	380	245	10	26	382	12	384	2e-28	128
tr:F3GC87_PSESJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.41	359	234	9	286	629	2	352	2e-28	127
rs:WP_044166537	DNA topoisomerase III, partial [Staphylococcus aureus].	32.60	273	156	5	353	615	9	263	2e-28	127
rs:WP_012716149	DNA topoisomerase I [Sulfolobus islandicus].	25.36	623	365	25	3	580	11	578	2e-28	131
rs:WP_012717494	DNA topoisomerase I [Sulfolobus islandicus].	25.36	623	365	25	3	580	11	578	2e-28	131
rs:WP_008084369	DNA topoisomerase I [Aciduliprofundum boonei].	23.28	640	423	23	3	619	4	598	2e-28	131
rs:WP_012711318	DNA topoisomerase I [Sulfolobus islandicus].	25.16	620	370	25	3	580	11	578	2e-28	131
rs:WP_036176735	hypothetical protein, partial [Lysinibacillus massiliensis].	30.89	327	185	11	3	312	5	307	2e-28	126
rs:WP_005538001	DNA topoisomerase I [Haloarcula argentinensis].	23.88	716	439	28	1	661	1	665	3e-28	131
rs:WP_012713672	DNA topoisomerase I [Sulfolobus islandicus].	25.36	623	365	25	3	580	11	578	3e-28	131
rs:WP_043511603	DNA topoisomerase III, partial [Halomonas sp. BC04].	28.26	322	219	6	266	581	4	319	3e-28	127
rs:WP_017648987	hypothetical protein, partial [Streptococcus agalactiae].	29.09	416	256	15	36	428	39	438	3e-28	128
rs:WP_008084733	DNA topoisomerase I [Aciduliprofundum boonei].	23.28	640	423	23	3	619	4	598	3e-28	131
rs:WP_042096603	DNA topoisomerase III, partial [Escherichia coli].	28.83	437	268	11	279	680	3	431	3e-28	128
rs:WP_031649808	DNA topoisomerase III, partial [Listeria innocua].	36.36	209	117	7	3	205	5	203	3e-28	123
rs:WP_033627137	DNA topoisomerase, partial [Enterococcus faecium].	29.35	385	237	9	41	399	12	387	3e-28	127
tr:A0A059N3S6_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.80	347	225	8	299	625	2	339	3e-28	126
rs:WP_032577053	DNA topoisomerase I, partial [Bacteroides fragilis].	26.91	446	287	11	161	593	1	420	3e-28	128
rs:WP_032072231	DNA topoisomerase III [Escherichia coli].	28.72	390	250	12	1	367	1	385	3e-28	127
rs:WP_033478926	DNA topoisomerase III, partial [Xanthomonas perforans].	29.34	317	203	8	1	305	1	308	3e-28	126
rs:WP_046420442	DNA topoisomerase, partial [Xylella fastidiosa].	32.96	267	152	7	1	247	1	260	3e-28	125
rs:WP_002347691	hypothetical protein, partial [Enterococcus faecium].	29.35	385	237	9	41	399	5	380	3e-28	127
tr:K1TDW7_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central domain protein {ECO:0000313|EMBL:EKC57406.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EKC57406.1}; Flags: Fragment;	29.69	320	205	8	349	656	22	333	3e-28	126
rs:WP_001235772	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	28.72	390	250	12	1	367	1	385	3e-28	127
rs:WP_019177234	hypothetical protein [Methanomassiliicoccus luminyensis].	24.56	676	405	30	2	630	3	620	3e-28	131
rs:WP_012695386	DNA topoisomerase [Lactobacillus brevis].	25.27	546	353	21	3	526	4	516	3e-28	130
rs:WP_001235771	hypothetical protein, partial [Salmonella enterica].	28.72	390	250	12	1	367	1	385	3e-28	127
tr:Q3MN56_LACPA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.45	310	204	6	286	581	4	303	3e-28	127
rs:WP_026485929	DNA topoisomerase I [Caldanaerobius polysaccharolyticus].	25.00	628	384	25	83	671	60	639	3e-28	130
rs:WP_023425866	DNA topoisomerase I, archaeal [uncultured Acidilobus sp. CIS].	24.15	646	406	23	4	612	16	614	3e-28	130
rs:WP_016730808	DNA topoisomerase I [Sulfolobus islandicus].	25.48	624	369	24	3	585	11	579	3e-28	130
tr:G4ADB7_AGGAC	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGY43437.1};	35.06	231	121	9	1	214	1	219	3e-28	125
rs:WP_047209062	DNA topoisomerase [Streptococcus agalactiae].	24.84	620	377	19	3	584	4	572	3e-28	129
rs:YP_004289757	DNA topoisomerase i [Methanobacterium lacus].	26.72	580	356	21	90	639	91	631	3e-28	130
tr:R8QQ92_BACCE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOP72678.1};	36.11	180	112	2	3	179	4	183	4e-28	123
tr:L1MU76_9BACT	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EKX94519.1};	31.80	283	174	6	4	275	5	279	4e-28	125
rs:WP_040085309	DNA topoisomerase III, partial [Escherichia coli].	31.95	338	200	10	348	663	34	363	4e-28	127
rs:WP_017768572	DNA topoisomerase III [Streptococcus agalactiae].	25.52	572	357	18	36	578	39	570	4e-28	129
tr:F8XV09_9GAMM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGQ63552.1}; Flags: Fragment;	32.61	230	137	6	1	218	1	224	4e-28	125
tr:I0IL87_LEPFC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.92	669	415	25	3	631	46	660	4e-28	131
rs:WP_032329999	DNA topoisomerase III, partial [Escherichia coli].	28.72	390	250	12	1	367	1	385	4e-28	127
rs:WP_008312743	DNA topoisomerase I [Haloarcula amylolytica].	24.55	660	401	26	1	616	1	607	4e-28	130
rs:WP_044061963	hypothetical protein, partial [Escherichia coli].	26.09	460	302	10	1	426	1	456	4e-28	127
rs:WP_041774651	DNA topoisomerase [Leptospirillum ferrooxidans].	23.92	669	415	25	3	631	12	626	4e-28	130
rs:WP_022042897	DNA topoisomerase III [Bacteroides caccae CAG:21].	28.48	330	222	9	351	677	1	319	4e-28	126
rs:WP_012718809	DNA topoisomerase I [Sulfolobus islandicus].	25.36	623	365	25	3	580	11	578	4e-28	130
tr:S4NCT1_9PORP	SubName: Full=DNA topoisomerase III, Bacteroidales-type {ECO:0000313|EMBL:GAD06918.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAD06918.1};	32.26	248	150	6	1	236	1	242	5e-28	124
rs:WP_013386983	DNA topoisomerase I [Ilyobacter polytropus].	25.86	665	379	25	3	627	6	596	5e-28	130
tr:A0A0D0FB34_LACBR	SubName: Full=Lactobacillus brevis strain TMW 1.313 Scaffold_5_TMW1313, whole genome shotgun sequence {ECO:0000313|EMBL:KIO93453.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIO93453.1};	27.10	310	202	6	286	581	4	303	5e-28	127
rs:WP_040180632	DNA topoisomerase III, partial [Klebsiella pneumoniae].	26.32	551	314	20	210	673	1	546	5e-28	129
rs:WP_011971973	DNA topoisomerase I [Methanococcus vannielii].	26.53	686	400	30	3	640	4	633	5e-28	130
rs:WP_001545303	DNA topoisomerase, partial [Escherichia coli].	33.18	211	129	5	1	205	1	205	5e-28	124
rs:WP_000557251	DNA topoisomerase III [Streptococcus agalactiae].	24.68	620	378	20	3	584	4	572	5e-28	129
tr:W7KLC0_9CREN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.12	617	378	20	3	585	9	575	5e-28	130
rs:WP_020189432	DNA topoisomerase I [Kurthia sp. Dielmo].	25.49	557	355	18	105	630	82	609	5e-28	130
rs:WP_015495977	DNA recombination protein RmuC [Octadecabacter arcticus].	25.96	597	376	21	3	560	5	574	6e-28	130
rs:WP_044708788	DNA topoisomerase III, partial [Escherichia coli].	35.37	229	127	9	1	215	1	222	6e-28	124
rs:WP_033714662	DNA topoisomerase III, partial [Bacillus cereus].	36.11	180	112	2	3	179	4	183	6e-28	122
rs:WP_004032475	MULTISPECIES: DNA topoisomerase I [Methanobrevibacter].	27.36	541	332	20	90	607	93	595	6e-28	130
rs:WP_031228895	DNA topoisomerase III, partial [Salmonella enterica].	25.50	349	237	6	250	578	1	346	6e-28	126
tr:L2HCI8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.71	483	317	14	218	673	23	495	7e-28	128
tr:I2WFK0_ECOLX	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EII23428.1};	29.50	339	205	10	1	317	1	327	7e-28	125
rs:WP_000259053	DNA topoisomerase III [Streptococcus agalactiae].	25.29	609	384	20	1	578	2	570	7e-28	129
rs:WP_031396094	DNA topoisomerase I, partial [Sphingomonas sp. STIS6.2].	24.96	669	407	24	1	629	1	614	7e-28	129
rs:WP_021678245	DNA topoisomerase, partial [Porphyromonas gingivalis].	28.84	371	219	13	172	513	1	355	7e-28	125
tr:F3GEY9_PSESJ	SubName: Full=Orf50 {ECO:0000313|EMBL:EGH45639.1};	26.67	360	240	7	344	684	13	367	7e-28	126
tr:M5AH10_LACBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.13	310	205	6	286	581	4	303	7e-28	126
rs:WP_003078034	toprim domain / DNA topoisomerase multi-domain protein [Streptococcus intermedius].	25.87	572	351	20	40	580	43	572	8e-28	129
rs:WP_027357341	DNA topoisomerase I [Desulfotomaculum thermocisternum].	25.49	561	353	22	88	616	62	589	8e-28	129
rs:WP_042902897	DNA topoisomerase [Streptococcus oralis].	26.24	564	354	19	40	578	43	569	8e-28	128
tr:U2E4L1_9BACE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERI89122.1};	28.30	417	280	11	271	677	25	432	8e-28	127
rs:WP_002376294	DNA topoisomerase [Enterococcus faecium].	27.73	375	249	8	219	581	1	365	9e-28	126
rs:WP_038167017	DNA topoisomerase III, partial [Vibrio shilonii].	26.34	524	330	19	161	640	11	522	9e-28	128
tr:K2CQ65_9BACT	RecName: Full=DNA topoisomerase I, plasmid {ECO:0000256|SAAS:SAAS00003555}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	26.09	667	397	22	2	629	3	612	9e-28	129
rs:WP_031834058	DNA topoisomerase III, partial [Staphylococcus aureus].	32.30	322	189	11	3	303	4	317	9e-28	124
rs:WP_025477999	DNA topoisomerase [Enterococcus faecium].	27.73	375	249	8	219	581	1	365	9e-28	125
rs:WP_033629029	DNA topoisomerase, partial [Enterococcus faecium].	27.43	339	227	7	347	667	5	342	9e-28	125
tr:K8B7E1_9ENTR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CCJ84182.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CCJ84182.1};	32.70	211	136	3	374	581	3	210	9e-28	123
rs:WP_013303640	DNA topoisomerase I [Ignisphaera aggregans].	25.42	649	405	25	3	615	8	613	9e-28	129
rs:WP_036882351	hypothetical protein, partial [Prevotella nigrescens].	30.08	379	231	13	309	673	1	359	9e-28	125
tr:Q3ES69_BACTI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.10	428	274	10	251	655	1	413	1e-27	129
rs:WP_042991435	DNA topoisomerase III, partial [Bifidobacterium adolescentis].	32.50	240	141	7	1	229	1	230	1e-27	123
tr:D4LFQ5_9FIRM	SubName: Full=Draft genome {ECO:0000313|EMBL:CBL18666.1};	36.87	198	107	6	3	193	4	190	1e-27	125
rs:WP_043895622	DNA topoisomerase I, partial [Porphyromonas gingivalis].	34.39	253	143	9	1	239	1	244	1e-27	123
tr:A0A075H2Q2_9EURY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.04	671	410	24	1	629	2	621	1e-27	129
rs:WP_004312554	toprim domain protein, partial [Bacteroides xylanisolvens].	33.09	275	158	10	1	259	1	265	1e-27	123
rs:WP_002322909	DNA topoisomerase III, partial [Enterococcus faecium].	30.56	301	176	8	3	280	4	294	1e-27	124
rs:WP_035038494	DNA topoisomerase I [Devosia sp. DBB001].	26.20	687	386	31	1	629	1	624	1e-27	129
tr:T3QMB3_PEPDI	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EQG75830.1};	37.56	213	109	8	3	204	5	204	1e-27	122
rs:WP_007994801	DNA topoisomerase I [Halorubrum arcis].	23.82	739	445	30	2	661	6	705	1e-27	129
rs:WP_034014013	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	28.81	295	185	9	1	278	1	287	1e-27	124
rs:WP_034949874	DNA topoisomerase III, partial [Erwinia oleae].	32.71	214	126	6	1	205	1	205	1e-27	122
rs:WP_013180152	DNA topoisomerase I [Methanococcus voltae].	28.12	633	348	26	3	587	4	577	1e-27	129
rs:WP_019789876	hypothetical protein [Streptococcus sobrinus].	25.48	573	340	19	46	580	49	572	1e-27	127
tr:A0A0B7H388_TREPH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.79	354	217	8	245	587	112	448	1e-27	126
rs:WP_041019761	DNA topoisomerase III, partial [Xanthomonas axonopodis].	29.03	310	207	5	266	562	24	333	2e-27	124
rs:WP_014736718	DNA topoisomerase I [Thermogladius cellulolyticus].	25.80	655	398	26	3	617	18	624	2e-27	128
rs:WP_039585037	DNA topoisomerase III, partial [Xanthomonas axonopodis].	29.03	310	207	5	266	562	18	327	2e-27	124
tr:R2W343_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOI37178.1};	37.33	217	114	7	3	204	4	213	2e-27	122
rs:WP_043964776	DNA topoisomerase I [Anoxybacillus thermarum].	25.25	503	321	18	156	630	131	606	2e-27	128
tr:Q2B124_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EAR63545.1};	29.28	362	207	13	301	646	1	329	2e-27	125
rs:WP_039575838	DNA topoisomerase III, partial [Xanthomonas axonopodis].	29.03	310	207	5	266	562	22	331	2e-27	124
rs:WP_036683311	DNA topoisomerase I, partial [Pelobacter seleniigenes].	25.59	723	412	30	3	663	5	663	2e-27	129
rs:WP_044531588	DNA topoisomerase III, partial [Herbaspirillum sp. B65].	26.21	393	256	10	308	680	5	383	2e-27	127
rs:WP_035308717	DNA topoisomerase, partial [Clostridium sp. HMP27].	32.88	295	165	9	2	272	3	288	2e-27	123
rs:WP_044635092	DNA topoisomerase, partial [Treponema phagedenis].	30.77	338	209	7	258	587	40	360	2e-27	124
rs:WP_012548590	DNA topoisomerase I [Dictyoglomus thermophilum].	25.24	717	413	28	2	675	5	641	2e-27	128
tr:A0A075H5S9_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.96	629	405	20	3	603	23	612	2e-27	128
tr:U2HJ00_LACPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	27.12	306	199	6	290	581	1	296	2e-27	124
rs:WP_007695272	DNA topoisomerase I [Halococcus hamelinensis].	23.15	717	444	28	1	661	1	666	2e-27	129
rs:WP_011019972	topoisomerase IA [Methanopyrus kandleri].	23.98	638	381	26	3	599	10	584	2e-27	127
rs:WP_018084360	hypothetical protein [Desulfurispora thermophila].	25.17	576	366	19	89	630	63	607	2e-27	128
rs:WP_046106690	DNA topoisomerase I [Devosia geojensis].	24.60	687	399	25	1	629	1	626	2e-27	128
rs:WP_014558129	DNA topoisomerase III [Fervidicoccus fontis].	24.69	644	400	23	3	610	15	609	2e-27	128
rs:WP_019264601	DNA topoisomerase I [Methanobrevibacter smithii].	27.17	541	333	20	90	607	93	595	2e-27	128
rs:WP_035690956	DNA topoisomerase III [Azospirillum halopraeferens].	24.01	629	406	17	3	585	4	606	2e-27	128
rs:WP_021094222	MULTISPECIES: DNA topoisomerase I [Anoxybacillus].	25.25	503	321	18	156	630	131	606	2e-27	128
rs:WP_020322465	toprim domain protein, partial [Klebsiella pneumoniae].	29.19	394	243	17	1	367	1	385	2e-27	124
rs:WP_004038803	DNA topoisomerase I [Methanofollis liminatans].	24.35	657	395	26	1	614	1	598	2e-27	128
rs:WP_017648563	DNA topoisomerase III [Streptococcus agalactiae].	25.89	564	356	19	40	578	43	569	3e-27	127
rs:WP_031440482	MULTISPECIES: DNA topoisomerase I [Sphingomonas].	24.07	727	454	26	1	686	1	670	3e-27	128
tr:S5SY71_LACPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.77	310	203	6	286	581	4	303	3e-27	125
rs:WP_008415922	DNA topoisomerase I [Halalkalicoccus jeotgali].	23.42	726	432	30	1	661	1	667	3e-27	128
rs:WP_022541864	DNA topoisomerase I [Aeropyrum camini].	23.26	576	377	19	68	613	81	621	3e-27	127
rs:WP_022238219	DNA topoisomerase [Clostridium sp. CAG:343].	35.83	240	121	9	2	219	4	232	3e-27	121
rs:WP_009992334	DNA topoisomerase I [Sulfolobus solfataricus].	25.48	624	363	25	3	580	11	578	3e-27	127
tr:R2NSX6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.17	438	285	12	157	578	21	440	3e-27	126
rs:WP_016628541	DNA topoisomerase [Enterococcus faecium].	27.91	326	216	6	265	581	3	318	3e-27	123
rs:WP_002355348	toprim domain protein, partial [Enterococcus faecium].	30.93	333	207	8	3	317	4	331	3e-27	123
sp:TOP1_THEAC	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.94	613	376	25	1	585	4	566	4e-27	127
rs:WP_040178475	DNA topoisomerase III, partial [Klebsiella pneumoniae].	35.65	216	122	7	1	205	1	210	4e-27	120
tr:R2SAC7_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.46	426	268	13	276	673	4	416	4e-27	124
tr:R9X141_LACPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.71	322	210	7	286	592	4	314	4e-27	124
rs:WP_037029714	DNA topoisomerase I, partial [Psychrilyobacter atlanticus].	26.43	666	391	27	3	633	6	607	4e-27	127
rs:WP_036889231	hypothetical protein, partial [Prevotella aurantiaca].	28.27	375	242	11	309	673	1	358	5e-27	124
rs:WP_002352070	DNA topoisomerase, partial [Enterococcus faecium].	26.06	376	240	10	290	639	5	368	5e-27	123
tr:K8E4W8_CARML	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CCO11554.2}; EC=5.99.1.2 {ECO:0000313|EMBL:CCO11554.2};	30.74	257	160	6	3	252	4	249	5e-27	121
rs:WP_000237215	DNA topoisomerase III [Streptococcus agalactiae].	25.21	603	387	20	3	578	4	569	5e-27	126
rs:WP_031879283	DNA topoisomerase III, partial [Staphylococcus aureus].	27.53	396	263	9	237	620	9	392	5e-27	124
rs:WP_031832854	DNA topoisomerase III, partial [Staphylococcus aureus].	38.16	207	114	6	3	204	4	201	5e-27	120
rs:WP_042957237	DNA topoisomerase, partial [Enterococcus faecium].	26.06	376	240	10	290	639	12	375	5e-27	123
rs:WP_031811378	DNA topoisomerase III, partial [Staphylococcus aureus].	38.16	207	114	6	3	204	4	201	5e-27	120
rs:WP_031837316	DNA topoisomerase III, partial [Staphylococcus aureus].	38.16	207	114	6	3	204	4	201	5e-27	120
tr:A0A090P938_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAK86565.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAK86565.1};	32.42	256	148	8	2	238	3	252	5e-27	121
rs:WP_034054043	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	30.42	263	160	7	1	250	1	253	5e-27	121
rs:WP_039943978	DNA topoisomerase, partial [Treponema phagedenis].	30.56	337	211	6	258	587	101	421	6e-27	124
rs:WP_012583876	DNA topoisomerase I [Dictyoglomus turgidum].	26.13	685	388	29	2	640	5	617	6e-27	127
rs:WP_041877706	DNA topoisomerase III, partial [Verrucomicrobia bacterium SCGC AAA164-O14].	25.73	443	289	14	259	678	21	446	6e-27	125
rs:WP_032703532	DNA topoisomerase III, partial [Campylobacter coli].	30.19	371	221	12	271	612	33	394	6e-27	123
rs:WP_032099733	DNA topoisomerase I [Anoxybacillus flavithermus].	25.45	503	320	18	156	630	131	606	6e-27	126
rs:WP_004891082	DNA topoisomerase I [Anoxybacillus flavithermus].	25.05	503	322	18	156	630	131	606	7e-27	126
tr:T0Y7L8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD31086.1}; Flags: Fragment;	28.99	338	225	8	250	580	10	339	7e-27	123
rs:WP_002350833	DNA topoisomerase, partial [Enterococcus faecium].	26.08	372	237	10	294	639	1	360	7e-27	123
rs:WP_014027476	DNA topoisomerase I [Pyrolobus fumarii].	23.41	581	378	18	68	618	74	617	8e-27	126
rs:WP_029749639	DNA topoisomerase, partial [Streptococcus agalactiae].	32.12	302	180	7	287	580	2	286	8e-27	121
tr:C6ANJ9_AGGAN	SubName: Full=DNA topoisomerase 3 (DNA topoisomerase III) {ECO:0000313|EMBL:ACS97410.1};	34.67	225	125	6	1	213	1	215	8e-27	119
rs:WP_006629579	DNA topoisomerase I [Halorubrum tebenquichense].	23.74	733	454	29	2	661	6	706	9e-27	126
rs:WP_012961161	DNA topoisomerase III [Bacillus pseudofirmus].	28.50	414	227	15	283	658	3	385	9e-27	123
rs:WP_003045441	DNA topoisomerase III [Streptococcus canis].	24.67	612	380	19	3	580	4	568	1e-26	125
rs:WP_035088805	DNA topoisomerase I [Devosia sp. 17-2-E-8].	26.06	687	387	31	1	629	1	624	1e-26	126
rs:WP_015497327	DNA recombination protein RmuC [Octadecabacter arcticus].	25.66	608	364	23	3	560	5	574	1e-26	126
tr:W6PRZ7_9BACE	SubName: Full=DNA topoisomerase III, Bacteroidales-type {ECO:0000313|EMBL:CDM06735.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDM06735.1};	30.56	252	157	4	1	241	1	245	1e-26	120
rs:WP_027970847	DNA topoisomerase III [Streptococcus castoreus].	25.12	617	371	21	3	580	4	568	1e-26	125
rs:WP_002308087	topoisomerase I [Enterococcus faecium].	38.22	191	107	5	40	221	11	199	1e-26	119
rs:WP_040177565	DNA topoisomerase III, partial [Klebsiella pneumoniae].	26.92	494	281	17	255	673	16	504	1e-26	124
rs:WP_040235486	DNA topoisomerase III, partial [Klebsiella pneumoniae].	26.92	494	281	17	255	673	6	494	1e-26	124
rs:WP_017113416	hypothetical protein [Xanthomonas campestris].	29.97	317	201	8	1	305	1	308	1e-26	122
rs:WP_032996320	DNA topoisomerase III, partial [Aggregatibacter aphrophilus].	34.68	222	123	6	1	210	1	212	1e-26	119
rs:WP_035020929	DNA topoisomerase I [Anoxybacillus flavithermus].	24.85	503	323	18	156	630	131	606	1e-26	125
rs:WP_015254980	DNA topoisomerase I [Thermobacillus composti].	25.52	627	384	26	103	687	80	665	1e-26	125
rs:WP_025068382	DNA topoisomerase, partial [Prevotella denticola].	28.12	345	233	9	344	684	18	351	1e-26	122
rs:WP_008323216	DNA topoisomerase I [Haloferax elongans].	23.44	721	438	27	3	661	7	675	1e-26	126
rs:WP_015738598	DNA topoisomerase I [Ammonifex degensii].	25.50	596	345	21	83	630	59	603	1e-26	125
rs:WP_012575317	DNA topoisomerase I [Anoxybacillus flavithermus].	24.37	554	362	19	105	630	82	606	1e-26	125
rs:WP_020221956	DNA topoisomerase I [Halarchaeum acidiphilum].	23.74	653	417	26	1	616	1	609	1e-26	126
tr:R4FEZ4_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.85	503	323	18	156	630	132	607	1e-26	125
rs:WP_004517003	DNA topoisomerase I [Haloarcula vallismortis].	23.94	660	405	25	1	616	1	607	1e-26	126
rs:WP_002303238	topoisomerase I [Enterococcus faecium].	38.02	192	108	5	40	222	11	200	1e-26	118
rs:WP_036295630	DNA topoisomerase, partial [Methylobacter whittenburyi].	30.32	277	154	6	266	537	17	259	1e-26	120
rs:WP_006927518	DNA topoisomerase I [Caldithrix abyssi].	24.52	677	408	27	3	637	9	624	1e-26	125
sp:TOP1_ARCFU	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.14	716	434	32	3	677	6	660	1e-26	125
rs:WP_041783995	DNA topoisomerase [Streptococcus anginosus].	25.83	604	378	21	2	576	3	565	2e-26	124
sp:TOP1_AERPE	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	23.95	572	378	19	68	613	61	601	2e-26	125
rs:WP_040609953	DNA topoisomerase III, partial [Salimicrobium sp. MJ3].	27.33	333	229	6	358	681	2	330	2e-26	121
rs:WP_023423913	DNA topoisomerase I, archaeal [uncultured Acidilobus sp. MG].	24.53	644	406	23	4	612	3	601	2e-26	125
rs:WP_021938600	DNA topoisomerase [Coprococcus sp. CAG:782].	26.67	435	270	16	188	578	28	457	2e-26	123
rs:WP_031897078	DNA topoisomerase III, partial [Staphylococcus aureus].	34.18	237	130	7	3	223	4	230	2e-26	119
rs:WP_036881465	DNA topoisomerase I, partial [Prevotella nigrescens].	28.27	382	234	15	309	673	1	359	2e-26	122
rs:WP_033502019	DNA topoisomerase III, partial [Bifidobacterium kashiwanohense].	24.21	442	289	12	277	677	1	437	2e-26	123
rs:WP_021954365	DNA topoisomerase [Clostridium sp. CAG:921].	24.32	662	393	23	2	629	4	591	2e-26	125
rs:WP_006111841	DNA topoisomerase I [Halorubrum coriense].	23.55	739	447	29	2	661	6	705	2e-26	125
rs:WP_002350554	toprim domain protein, partial [Enterococcus faecium].	30.41	296	183	8	3	280	4	294	2e-26	120
rs:WP_023860402	topoisomerase IA [Lactobacillus equi].	23.75	699	427	26	3	630	7	670	2e-26	125
rs:WP_004051361	DNA topoisomerase I [Halococcus morrhuae].	23.09	719	443	29	1	661	1	667	2e-26	125
rs:WP_012035064	DNA topoisomerase I [Methanocella arvoryzae].	24.09	660	424	26	1	629	1	614	2e-26	125
tr:K1U2L6_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC72560.1}; Flags: Fragment;	36.81	182	98	5	3	177	4	175	2e-26	117
tr:R2NT98_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOH42604.1};	27.16	335	225	7	351	667	1	334	2e-26	121
rs:WP_023429490	DNA topoisomerase I, archaeal [uncultured Acidilobus sp. JCHS].	24.88	647	400	24	4	612	3	601	2e-26	125
rs:WP_031921633	DNA topoisomerase III, partial [Staphylococcus aureus].	26.97	356	244	6	271	620	4	349	2e-26	122
rs:WP_002305037	type I topoisomerase, partial [Enterococcus faecium].	33.33	228	143	5	3	222	4	230	2e-26	119
rs:WP_013008503	DNA topoisomerase I [Deferribacter desulfuricans].	25.71	634	383	24	74	667	51	636	2e-26	125
rs:WP_014705479	DNA topoisomerase I [Methylophaga nitratireducenticrescens].	25.29	688	382	31	2	630	4	618	2e-26	125
rs:WP_008628880	DNA topoisomerase, partial [Paraprevotella xylaniphila].	30.28	317	199	9	228	536	23	325	2e-26	120
rs:WP_036747808	DNA topoisomerase I [Peptococcaceae bacterium SCADC1_2_3].	26.16	562	350	19	89	616	63	593	2e-26	125
rs:WP_031838147	hypothetical protein [Staphylococcus aureus].	34.18	237	130	7	3	223	4	230	2e-26	119
rs:WP_013898006	DNA topoisomerase I [Methanosalsum zhilinae].	25.53	666	414	31	1	629	1	621	3e-26	125
rs:WP_006664395	DNA topoisomerase I [Natrialba aegyptia].	22.42	718	449	26	1	661	1	667	3e-26	125
rs:WP_021060176	Topoisomerase IA, partial [Halonotius sp. J07HN6].	22.33	730	443	28	3	660	7	684	3e-26	124
tr:A0A075WFN2_ARCFL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.14	716	434	32	3	677	4	658	3e-26	124
rs:WP_044444178	DNA topoisomerase I, partial [Bacillus mycoides].	26.87	428	275	10	251	655	39	451	3e-26	124
rs:WP_031884499	DNA topoisomerase III, partial [Staphylococcus aureus].	26.97	356	244	6	271	620	36	381	3e-26	122
rs:WP_033604912	MULTISPECIES: DNA topoisomerase, partial [Enterococcus].	27.40	292	200	5	349	629	41	331	3e-26	120
tr:T0MDS8_9SPHI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EQB80794.1};	29.76	336	210	13	347	673	7	325	3e-26	120
tr:R3QFQ2_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOL03019.1}; Flags: Fragment;	27.40	292	200	5	349	629	30	320	3e-26	120
rs:WP_042853364	DNA topoisomerase III, partial [Staphylococcus aureus].	26.97	356	244	6	271	620	4	349	3e-26	122
rs:WP_018509290	DNA topoisomerase I [Thiobacillus thioparus].	24.41	676	386	27	2	630	3	600	3e-26	125
rs:XP_012455603	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Gossypium raimondii].	24.92	626	383	26	3	586	8	588	3e-26	125
rs:WP_031921854	DNA topoisomerase III, partial [Staphylococcus aureus].	26.97	356	244	6	271	620	37	382	3e-26	122
rs:WP_041076433	DNA topoisomerase I [Thermotoga caldifontis].	24.92	646	383	21	2	612	4	582	3e-26	124
tr:C9BIL0_ENTFC	SubName: Full=Topoisomerase {ECO:0000313|EMBL:EEV52135.1};	38.22	191	107	5	41	222	12	200	4e-26	117
tr:A5ZUI1_9FIRM	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EDM86761.1};	33.91	233	136	6	3	221	5	233	4e-26	119
tr:L9PR83_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELX66133.1};	30.56	337	206	11	351	673	1	323	4e-26	120
tr:A0A0B3A8L9_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.12	649	393	25	3	612	127	721	4e-26	124
tr:A0A0D6S764_BACMY	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KIV64387.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIV64387.1};	26.87	428	275	10	251	655	20	432	4e-26	124
rs:WP_008009864	DNA topoisomerase I [Haloterrigena limicola].	23.00	726	435	29	1	661	1	667	4e-26	124
rs:WP_000237217	DNA topoisomerase III [Streptococcus oralis].	26.24	564	354	20	40	578	43	569	4e-26	123
rs:WP_009730737	DNA topoisomerase III [Streptococcus sp. F0441].	25.08	610	379	21	3	578	4	569	5e-26	123
tr:F8XQZ5_9GAMM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGQ62138.1}; Flags: Fragment;	29.08	282	190	6	348	625	17	292	5e-26	120
rs:WP_027116342	DNA topoisomerase III [Lachnospiraceae bacterium P6B14].	27.42	383	218	14	253	581	340	716	5e-26	124
rs:WP_027116342	DNA topoisomerase III [Lachnospiraceae bacterium P6B14].	30.08	236	141	8	2	219	4	233	1e-20	107
rs:WP_018076642	DNA topoisomerase I [Thiobacillus denitrificans].	24.12	684	378	27	2	630	3	600	5e-26	124
rs:WP_036846570	DNA topoisomerase I, partial [Porphyromonas sp. COT-108 OH1349].	35.14	222	126	6	1	212	1	214	5e-26	117
rs:WP_031910302	DNA topoisomerase III, partial [Staphylococcus aureus].	38.31	201	110	6	3	198	4	195	5e-26	116
tr:R2PZL1_9ENTE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOH89812.1};	32.77	235	140	5	3	224	4	233	5e-26	119
rs:WP_034194828	hypothetical protein, partial [Burkholderia sp. WP42].	29.51	288	182	7	348	614	1	288	5e-26	119
rs:WP_033482235	DNA topoisomerase III, partial [Xanthomonas axonopodis].	29.34	317	203	8	1	305	1	308	5e-26	119
rs:WP_033872209	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	33.64	214	123	6	1	205	1	204	5e-26	117
gpu:CP011267_459	DNA topoisomerase I [Geoglobus ahangari]	24.42	684	407	31	1	640	1	618	6e-26	123
rs:WP_041658130	DNA topoisomerase I, partial [Marinithermus hydrothermalis].	25.27	653	372	24	3	616	6	581	6e-26	124
rs:WP_043544899	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	27.35	351	225	10	300	629	1	342	6e-26	120
rs:WP_033869926	DNA topoisomerase III, partial [Staphylococcus aureus].	32.49	317	185	11	3	298	4	312	6e-26	119
rs:WP_022011721	DNA topoisomerase III [Bacteroides fragilis CAG:558].	30.07	296	186	7	306	588	1	288	6e-26	120
tr:H0AA89_HALSG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.53	587	370	17	3	560	5	547	6e-26	123
rs:WP_024992717	hypothetical protein, partial [Prevotella amnii].	34.91	212	119	6	4	204	5	208	6e-26	117
tr:T1ZSD4_STRAP	SubName: Full=Putative DNA topoisomerase III {ECO:0000313|EMBL:AGU81119.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AGU81119.1};	26.17	554	350	18	46	576	17	534	7e-26	122
tr:F2NLP3_MARHT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.27	653	372	24	3	616	6	581	7e-26	124
tr:A0A0D8DM63_9EURY	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJE49771.1};	27.84	564	331	22	46	585	53	564	7e-26	124
rs:WP_022466959	DNA topoisomerase [Subdoligranulum sp. CAG:314].	25.81	709	419	27	1	673	1	638	7e-26	124
rs:WP_012106401	DNA topoisomerase I [Methanoregula boonei].	24.89	679	401	31	1	630	1	619	7e-26	124
rs:WP_044653610	DNA topoisomerase I, partial [Bacteroides acidifaciens].	31.48	270	168	8	131	390	17	279	7e-26	118
rs:WP_042702305	DNA topoisomerase I [Methanobrevibacter arboriphilus].	27.49	582	338	23	90	631	92	629	7e-26	123
rs:WP_038663823	DNA topoisomerase I [Sphingomonas taxi].	23.92	715	457	23	1	680	1	663	7e-26	124
rs:WP_033874207	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	31.17	247	147	7	1	234	1	237	7e-26	117
rs:WP_015505040	DNA topoisomerase I [Candidatus Methanomethylophilus alvus].	23.99	667	419	22	2	630	4	620	7e-26	124
rs:WP_031838440	DNA topoisomerase III, partial [Staphylococcus aureus].	38.50	200	109	6	3	197	4	194	8e-26	116
rs:WP_007979591	DNA topoisomerase I [Haladaptatus paucihalophilus].	22.89	734	426	29	1	661	1	667	8e-26	123
rs:WP_036866467	DNA topoisomerase I, partial [Prevotella melaninogenica].	35.35	215	120	6	1	204	2	208	8e-26	117
rs:WP_027866354	hypothetical protein [Massilia alkalitolerans].	24.58	480	290	17	3	426	1	464	9e-26	121
rs:WP_022532720	DNA topoisomerase [Methanoculleus sp. CAG:1088].	23.99	667	419	22	2	630	4	620	9e-26	123
rs:WP_021044116	DNA topoisomerase I [halophilic archaeon J07HX64].	23.49	711	447	29	1	661	1	664	9e-26	123
rs:WP_035168818	topoisomerase I, partial [Lactobacillus curieae].	31.72	309	195	9	3	296	4	311	9e-26	119
tr:C0EHG4_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.33	547	329	19	163	674	151	658	9e-26	123
rs:WP_040438574	DNA topoisomerase I [[Clostridium] methylpentosum].	26.33	547	329	19	163	674	142	649	9e-26	123
rs:WP_033120310	DNA topoisomerase I [Oscillibacter sp. ER4].	25.00	556	359	16	90	616	68	594	9e-26	123
rs:WP_019152799	DNA topoisomerase I [Bacillus massiliosenegalensis].	25.00	576	374	20	90	635	67	614	9e-26	123
rs:WP_003394922	DNA topoisomerase I [Anoxybacillus flavithermus].	24.55	554	361	19	105	630	82	606	9e-26	123
rs:WP_039583461	DNA topoisomerase III, partial [Xanthomonas axonopodis].	28.71	317	205	8	1	305	1	308	9e-26	119
rs:WP_014767919	DNA topoisomerase I [Desulfurococcus fermentans].	23.92	602	372	21	46	607	62	617	9e-26	123
rs:WP_042706517	DNA topoisomerase I [Methanomicrobium mobile].	23.29	700	428	29	1	650	1	641	9e-26	123
rs:WP_004598104	DNA topoisomerase I [Halorubrum distributum].	23.72	742	442	31	2	661	6	705	9e-26	123
rs:WP_042667972	DNA topoisomerase I [Desulfurococcus amylolyticus].	24.09	602	371	21	46	607	58	613	1e-25	122
rs:WP_019418404	DNA topoisomerase I [Anoxybacillus kamchatkensis].	25.25	503	321	17	156	630	131	606	1e-25	123
rs:WP_033795164	DNA topoisomerase, partial [Enterococcus faecium].	26.55	339	230	7	347	667	21	358	1e-25	120
rs:WP_027117982	DNA topoisomerase III [Lachnospiraceae bacterium YSB2008].	29.05	358	224	13	258	590	320	672	1e-25	122
rs:WP_027117982	DNA topoisomerase III [Lachnospiraceae bacterium YSB2008].	32.64	239	139	6	2	224	3	235	3e-25	121
rs:WP_044960689	DNA topoisomerase III, partial [Blautia sp. KLE 1732].	31.69	325	182	12	378	679	13	320	1e-25	119
rs:WP_043036435	DNA topoisomerase [Streptococcus equi].	24.47	617	375	21	3	580	4	568	1e-25	122
rs:WP_012966107	DNA topoisomerase I [Ferroglobus placidus].	25.07	682	398	30	1	639	1	612	1e-25	122
rs:WP_033709859	MULTISPECIES: DNA topoisomerase I, partial [Bacillus cereus group].	26.58	444	286	12	254	673	1	428	1e-25	122
tr:D7WI62_BACCE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFI65102.1};	25.70	428	275	11	1	392	1	421	1e-25	120
rs:WP_009732875	DNA topoisomerase I [Anoxybacillus sp. DT3-1].	24.65	503	324	18	156	630	131	606	1e-25	122
rs:WP_020431209	hypothetical protein, partial [Paenibacillus riograndensis].	24.75	493	274	18	274	678	12	495	1e-25	120
tr:W2CME8_9PORP	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETK08424.1};	30.04	243	162	6	347	583	19	259	1e-25	117
rs:WP_012608703	DNA topoisomerase I [Desulfurococcus kamchatkensis].	23.92	602	372	21	46	607	63	618	1e-25	122
rs:WP_008366091	DNA topoisomerase I [Halorubrum litoreum].	23.58	742	443	31	2	661	6	705	1e-25	123
rs:WP_033727875	DNA topoisomerase I, partial [Bacillus weihenstephanensis].	26.59	440	283	12	258	673	4	427	1e-25	122
rs:WP_022135741	DNA topoisomerase [Firmicutes bacterium CAG:176].	23.08	624	400	18	88	675	64	643	1e-25	122
rs:WP_036875141	hypothetical protein, partial [Prevotella nigrescens].	27.66	376	243	12	309	673	1	358	1e-25	119
tr:A0A085UHC4_9STAP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KFE42587.1};	32.93	246	156	4	4	240	6	251	2e-25	117
rs:WP_011181594	DNA topoisomerase I, partial [Bacillus thuringiensis].	28.78	337	212	8	65	384	10	335	2e-25	118
rs:WP_043872469	DNA topoisomerase I [Legionella massiliensis].	25.51	643	383	31	55	641	29	631	2e-25	122
rs:WP_037565328	DNA topoisomerase III, partial [Staphylococcus agnetis].	34.06	229	142	4	4	223	6	234	2e-25	116
tr:S5W9P8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.32	343	207	8	47	366	4	337	2e-25	119
tr:L9PZY6_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELX68407.1};	28.57	336	214	11	351	673	1	323	2e-25	118
rs:WP_035520262	DNA topoisomerase I [Haemophilus parasuis].	25.04	603	376	19	60	633	87	642	2e-25	122
rs:WP_025477514	DNA topoisomerase, partial [Enterococcus faecium].	29.59	338	205	8	3	317	4	331	2e-25	118
tr:T8F165_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	29.59	338	205	8	3	317	5	332	2e-25	118
tr:D4RGS5_ENTFC	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EFF26847.1}; Flags: Fragment;	32.89	228	135	5	3	217	4	226	2e-25	116
rs:WP_010466538	DNA topoisomerase [Pseudomonas mandelii].	27.35	501	290	17	76	537	51	516	2e-25	122
rs:WP_031842634	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	33.77	231	136	7	2	221	3	227	2e-25	117
rs:WP_013562560	DNA topoisomerase I [Desulfurococcus mucosus].	25.04	619	387	26	3	588	23	597	2e-25	122
rs:WP_007545055	DNA topoisomerase I [Haloferax larsenii].	23.16	721	440	27	3	661	7	675	2e-25	122
rs:WP_025477723	DNA topoisomerase, partial [Enterococcus faecium].	29.59	338	205	8	3	317	4	331	2e-25	118
rs:WP_008848835	DNA topoisomerase I [Halorubrum kocurii].	23.43	747	438	32	2	661	6	705	2e-25	122
rs:WP_040682714	DNA topoisomerase I, partial [Methanocaldococcus villosus].	30.09	422	235	18	1	393	1	391	2e-25	122
rs:WP_043339226	DNA topoisomerase III [Belnapia moabensis].	23.42	585	389	18	44	587	31	597	2e-25	122
rs:WP_041153557	hypothetical protein [Lactobacillus plantarum].	26.13	310	205	6	286	581	4	303	2e-25	119
rs:WP_037995540	DNA topoisomerase III, partial [Tannerella sp. oral taxon BU063].	30.29	241	160	6	347	581	24	262	2e-25	116
tr:A0A031LP74_9CREN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.34	517	335	14	88	587	92	574	2e-25	121
rs:WP_023650178	DNA topoisomerase III family protein, partial [Vibrio parahaemolyticus].	33.77	231	136	7	2	221	3	227	2e-25	116
rs:WP_035218062	DNA topoisomerase I, partial [Acidithiobacillus thiooxidans].	25.75	668	374	27	1	623	1	591	2e-25	121
rs:WP_021114792	DNA topoisomerase I [Haemophilus parasuis].	25.04	603	376	19	60	633	87	642	2e-25	122
rs:WP_007344964	DNA topoisomerase I [Halorubrum terrestre].	23.58	742	443	31	2	661	6	705	2e-25	122
tr:D3LK86_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	29.59	338	205	8	3	317	5	332	3e-25	118
rs:WP_036889264	hypothetical protein, partial [Prevotella aurantiaca].	28.27	375	242	12	309	673	1	358	3e-25	118
rs:WP_007047795	DNA topoisomerase I [Subdoligranulum variabile].	24.45	724	425	28	2	678	3	651	3e-25	121
rs:WP_002348936	DNA topoisomerase, partial [Enterococcus faecium].	25.66	339	233	7	347	667	27	364	3e-25	118
rs:WP_021115833	DNA topoisomerase I [Haemophilus parasuis].	25.33	604	373	20	60	633	87	642	3e-25	122
rs:WP_004253452	DNA topoisomerase I [Streptococcus mitis].	25.17	576	364	21	83	629	71	608	3e-25	121
rs:WP_010286439	DNA topoisomerase I [Kurthia massiliensis].	24.29	564	353	19	105	630	82	609	3e-25	121
rs:WP_023114036	hypothetical protein, partial [Pseudomonas aeruginosa].	33.65	211	125	6	1	204	1	203	3e-25	114
tr:I0TDW9_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EID33822.1};	31.84	267	166	5	274	533	2	259	3e-25	116
rs:WP_036889132	DNA topoisomerase I, partial [Prevotella enoeca].	33.20	253	159	5	269	520	71	314	3e-25	117
rs:WP_019774270	hypothetical protein, partial [Streptococcus sobrinus].	29.41	391	227	13	46	408	49	418	3e-25	118
rs:WP_028388168	DNA topoisomerase I [Legionella fairfieldensis].	26.04	626	378	28	55	630	29	619	4e-25	121
rs:WP_033584657	DNA topoisomerase [Streptococcus sp. SR1].	25.53	564	358	20	40	578	43	569	4e-25	120
rs:WP_010902213	DNA topoisomerase I [Halobacterium salinarum].	22.22	720	448	28	1	661	1	667	4e-25	121
rs:WP_023114038	hypothetical protein, partial [Pseudomonas aeruginosa].	33.65	211	125	6	1	204	1	203	4e-25	114
rs:WP_039730782	DNA topoisomerase III, partial [Enterococcus mundtii].	30.77	234	149	5	41	267	3	230	4e-25	115
rs:WP_035490613	DNA topoisomerase I [Haemophilus parasuis].	25.33	604	373	20	60	633	87	642	4e-25	121
rs:WP_010782788	hypothetical protein, partial [Enterococcus faecium].	25.66	339	233	7	347	667	2	339	4e-25	118
rs:WP_016171183	hypothetical protein, partial [Enterococcus faecium].	25.66	339	233	7	347	667	8	345	4e-25	118
rs:WP_010785769	DNA topoisomerase I subunit omega [Haemophilus parasuis].	25.33	604	373	20	60	633	87	642	4e-25	121
rs:WP_012621609	topoisomerase I [Haemophilus parasuis].	25.33	604	373	20	60	633	87	642	4e-25	121
rs:WP_021423285	toprim domain protein, partial [Peptoclostridium difficile].	36.84	171	99	4	1	168	1	165	4e-25	113
rs:WP_046985670	DNA topoisomerase III, partial [Thermomonas brevis].	28.12	345	223	11	301	629	1	336	4e-25	117
gp:CP005384_1002	DNA topoisomerase I subunit omega [Haemophilus parasuis ZJ0906]	25.33	604	373	20	60	633	29	584	4e-25	121
rs:WP_031868973	DNA topoisomerase III, partial [Staphylococcus aureus].	38.19	199	109	6	3	196	4	193	4e-25	114
rs:WP_045614986	DNA topoisomerase I [Streptococcus mitis].	25.17	576	364	21	83	629	71	608	4e-25	121
rs:WP_000237216	DNA topoisomerase III [Streptococcus pneumoniae].	25.35	564	359	18	40	578	43	569	4e-25	120
rs:WP_044021390	DNA topoisomerase [Streptococcus sp. VT 162].	25.71	564	357	20	40	578	43	569	4e-25	120
rs:WP_029498225	DNA topoisomerase I [Kurthia huakuii].	24.60	557	360	18	105	630	82	609	4e-25	121
rs:WP_031942101	DNA topoisomerase III, partial [Staphylococcus aureus].	26.65	349	240	6	278	620	1	339	4e-25	118
tr:A0A0B5HG25_9ARCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.53	693	450	26	1	660	1	653	5e-25	120
rs:WP_013129043	DNA topoisomerase I [Thermosphaera aggregans].	24.92	666	385	24	3	615	25	628	5e-25	120
rs:WP_045165305	DNA topoisomerase I [Thermoanaerobacter cellulolyticus].	25.81	585	358	18	83	629	59	605	5e-25	120
tr:W4LWV6_9DELT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETX02400.1}; Flags: Fragment;	31.56	244	147	5	458	682	8	250	5e-25	117
rs:WP_026916483	DNA topoisomerase I [Haemophilus parasuis].	25.04	603	376	19	60	633	87	642	5e-25	121
rs:WP_035495014	DNA topoisomerase I [Haemophilus parasuis].	25.33	604	373	20	60	633	87	642	5e-25	121
rs:WP_006109876	DNA topoisomerase I [Natrialba asiatica].	22.44	722	444	27	1	661	1	667	5e-25	121
rs:WP_044456509	DNA topoisomerase, partial [Bacillus subtilis].	30.86	256	161	4	436	675	1	256	5e-25	115
rs:WP_021109419	DNA topoisomerase I [Haemophilus parasuis].	25.33	604	373	20	60	633	87	642	5e-25	121
tr:A0A0C7NLR7_9THEO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.80	566	346	20	88	616	62	590	6e-25	120
rs:WP_008735261	topoisomerase I [Alcanivorax pacificus].	24.69	478	301	12	186	631	199	649	6e-25	121
rs:WP_010301563	DNA topoisomerase I [Kurthia sp. JC8E].	24.06	557	363	18	105	630	82	609	6e-25	120
rs:WP_008577482	MULTISPECIES: DNA topoisomerase I [Haloferax].	23.21	728	433	28	2	661	6	675	6e-25	120
rs:WP_021049991	Topoisomerase IA [Haloquadratum walsbyi].	22.86	735	435	31	2	661	6	683	6e-25	120
rs:WP_002169243	DNA topoisomerase III [Bacillus cereus].	36.87	198	109	8	3	194	5	192	6e-25	114
rs:WP_044009045	DNA topoisomerase I [Haemophilus parasuis].	25.33	604	373	20	60	633	87	642	6e-25	120
rs:WP_039209848	DNA topoisomerase, partial [Anaerovibrio lipolyticus].	32.16	227	138	7	1	219	1	219	6e-25	114
rs:WP_005607588	topoisomerase I [Actinobacillus pleuropneumoniae].	24.92	594	368	19	74	631	88	639	6e-25	120
rs:WP_038514169	DNA topoisomerase I [Haemophilus parasuis].	25.04	603	376	19	60	633	87	642	6e-25	120
rs:WP_035525139	DNA topoisomerase I [Haemophilus parasuis].	24.96	605	374	20	60	633	87	642	7e-25	120
rs:WP_021116753	DNA topoisomerase I [Haemophilus parasuis].	25.25	606	371	21	60	633	87	642	7e-25	120
rs:WP_014406759	DNA topoisomerase I [Methanocella conradii].	23.95	693	433	26	1	650	19	660	7e-25	120
rs:WP_035065874	DNA topoisomerase I [Anoxybacillus gonensis].	24.85	503	323	18	156	630	131	606	7e-25	120
rs:WP_005710869	topoisomerase I [Haemophilus parasuis].	25.33	604	373	20	60	633	87	642	7e-25	120
rs:WP_008005249	DNA topoisomerase I [Halorubrum lipolyticum].	23.28	743	444	30	2	661	6	705	7e-25	120
rs:WP_041438427	hypothetical protein, partial [Thermodesulfobium narugense].	28.18	582	354	20	77	629	57	603	7e-25	120
tr:M3GG24_9STRE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.95	297	191	6	276	558	4	291	7e-25	115
rs:WP_025064897	DNA topoisomerase, partial [Prevotella disiens].	27.25	378	242	13	309	673	2	359	7e-25	117
rs:WP_031861946	DNA topoisomerase III, partial [Staphylococcus aureus].	28.08	349	233	7	141	479	8	348	7e-25	117
rs:WP_014345297	DNA topoisomerase I [Sulfobacillus acidophilus].	23.51	672	408	23	3	630	7	616	7e-25	120
rs:WP_037534984	DNA topoisomerase I [Sphingomonas sp. RIT328].	23.88	716	457	24	1	680	1	664	7e-25	120
rs:WP_002201903	DNA topoisomerase III [Bacillus cereus].	36.36	198	110	8	3	194	5	192	7e-25	113
rs:WP_015499506	DNA recombination protein RmuC [Octadecabacter antarcticus].	25.12	601	376	22	3	560	5	574	7e-25	120
rs:WP_021110589	DNA topoisomerase I [Haemophilus parasuis].	25.25	606	371	21	60	633	87	642	8e-25	120
tr:K8EI91_CARML	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.32	346	203	13	279	614	1	311	8e-25	117
rs:WP_014758637	MULTISPECIES: DNA topoisomerase I [Thermoanaerobacterium].	26.12	559	343	15	90	616	67	587	8e-25	120
rs:WP_000237218	DNA topoisomerase III [Streptococcus sp. oral taxon 071].	25.71	564	357	19	40	578	43	569	8e-25	119
rs:WP_003001546	DNA topoisomerase I [Streptococcus parasanguinis].	25.87	576	360	23	83	629	69	606	8e-25	120
rs:WP_026475992	DNA topoisomerase I [Alkaliphilus transvaalensis].	24.82	685	400	27	3	644	5	617	9e-25	120
tr:M1E7D1_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.18	582	354	20	77	629	57	603	9e-25	120
rs:WP_025068440	DNA topoisomerase, partial [Prevotella denticola].	29.03	341	219	10	344	673	18	346	9e-25	117
rs:WP_021112282	DNA topoisomerase I [Haemophilus parasuis].	24.96	605	374	20	60	633	87	642	9e-25	120
rs:WP_042866267	DNA topoisomerase III, partial [Bacillus cereus].	35.75	221	131	7	107	321	2	217	9e-25	114
rs:WP_013822097	DNA topoisomerase I [Desulfotomaculum kuznetsovii].	25.89	560	350	22	89	616	63	589	9e-25	120
tr:F9MPK6_9FIRM	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EGS33035.1};	28.05	303	173	9	1	274	1	287	1e-24	115
rs:WP_016119355	DNA topoisomerase 1, partial [Bacillus cereus].	30.72	293	187	9	32	315	37	322	1e-24	116
rs:WP_033874173	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	30.84	214	129	5	1	205	1	204	1e-24	115
tr:I4Z0W6_9RHIZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.61	577	348	22	11	521	2	557	1e-24	119
rs:WP_017169014	hypothetical protein, partial [Xanthomonas axonopodis].	26.49	302	201	11	352	639	25	319	1e-24	116
rs:WP_026799764	DNA topoisomerase I [Pontibacillus halophilus].	24.57	578	374	21	90	635	67	614	1e-24	119
rs:WP_015756822	DNA topoisomerase I [Desulfotomaculum acetoxidans].	23.80	647	399	23	3	616	5	590	1e-24	119
rs:WP_017168549	hypothetical protein, partial [Xanthomonas axonopodis].	26.49	302	201	11	352	639	23	317	1e-24	116
rs:WP_005976360	DNA topoisomerase I [Fusobacterium ulcerans].	26.96	575	349	22	90	633	68	602	1e-24	120
rs:WP_032212518	DNA topoisomerase III, partial [Escherichia coli].	28.94	349	218	11	1	328	1	340	1e-24	116
gpu:CP008874_633	DNA topoisomerase I [Halanaeroarchaeum sulfurireducens]	22.55	674	399	26	1	616	1	609	1e-24	120
rs:WP_031887218	DNA topoisomerase III, partial [Staphylococcus aureus].	33.85	257	149	8	3	244	4	254	1e-24	115
rs:WP_035078850	DNA topoisomerase I [Devosia riboflavina].	23.73	687	403	22	1	629	1	624	1e-24	120
rs:XP_010039956	PREDICTED: DNA topoisomerase 3-beta [Eucalyptus grandis].	24.11	672	427	22	3	631	7	638	1e-24	120
rs:WP_033704523	DNA topoisomerase, partial [Enterococcus faecium].	31.67	240	151	6	3	230	4	242	1e-24	114
tr:T1AUZ1_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD60138.1}; Flags: Fragment;	29.14	278	185	8	250	520	58	330	1e-24	115
rs:WP_006190095	DNA topoisomerase I [Treponema vincentii].	24.92	658	381	25	3	618	18	604	1e-24	119
rs:WP_043411100	DNA topoisomerase III, partial [Streptomyces pluripotens].	35.81	215	115	7	3	205	5	208	1e-24	113
tr:U2CVW3_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ERI94679.1};	31.35	319	179	12	384	679	2	303	1e-24	115
rs:WP_003011242	DNA topoisomerase I [Streptococcus parasanguinis].	25.87	576	360	23	83	629	71	608	1e-24	119
tr:F0I7E3_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.26	578	361	21	83	629	73	610	1e-24	119
tr:A0A0B8NL35_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.07	276	171	7	65	318	14	289	1e-24	115
rs:WP_008442944	DNA topoisomerase I [Halorubrum californiense].	23.00	739	451	29	2	661	6	705	1e-24	120
rs:WP_006152356	DNA topoisomerase I [Streptococcus infantis].	25.22	579	360	22	83	629	53	590	1e-24	119
rs:WP_007520053	DNA topoisomerase III [Streptococcus tigurinus].	25.61	570	350	20	40	578	43	569	1e-24	119
rs:WP_032915919	DNA topoisomerase I [Streptococcus sanguinis].	25.26	578	361	21	83	629	70	607	1e-24	119
rs:WP_035720077	DNA topoisomerase I [Francisella sp. W12-1067].	27.32	604	357	26	74	629	51	620	1e-24	119
rs:XP_007163790	hypothetical protein PHAVU_001G264300g [Phaseolus vulgaris].	23.82	613	402	20	3	586	9	585	2e-24	119
tr:J6Y116_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EJY32199.1}; Flags: Fragment;	31.84	223	143	5	3	217	4	225	2e-24	114
rs:WP_028494122	DNA topoisomerase I [Thermus antranikianii].	25.04	595	343	23	77	616	49	595	2e-24	119
tr:F8I2K1_SULAT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.27	585	362	20	90	630	60	607	2e-24	119
rs:WP_000962891	hypothetical protein, partial [Vibrio cholerae].	32.08	240	146	4	350	581	1	231	2e-24	114
rs:WP_008824362	hypothetical protein, partial [Prevotella histicola].	27.94	340	224	9	344	673	16	344	2e-24	116
rs:WP_022134546	DNA topoisomerase [Clostridium sp. CAG:594].	26.17	665	378	28	3	629	5	594	2e-24	119
rs:WP_036885373	DNA topoisomerase I, partial [Prevotella disiens].	35.44	206	114	6	4	198	5	202	2e-24	112
rs:WP_011177548	DNA topoisomerase I [Picrophilus torridus].	26.48	627	371	30	46	638	53	623	2e-24	119
rs:WP_007275720	DNA topoisomerase I [Haloferax sulfurifontis].	23.52	727	432	29	2	661	6	675	2e-24	119
rs:WP_021113464	DNA topoisomerase I [Haemophilus parasuis].	24.88	603	373	20	60	631	87	640	2e-24	119
rs:WP_022655238	DNA topoisomerase I [Desulfovibrio sp. Dsv1].	22.90	642	384	19	1	611	1	562	2e-24	119
rs:WP_009725216	DNA topoisomerase I [Methylophaga lonarensis].	24.86	704	414	30	2	656	4	641	2e-24	119
tr:J6HK20_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EJY30873.1}; Flags: Fragment;	31.58	228	147	5	3	222	4	230	2e-24	114
rs:WP_044119010	DNA topoisomerase III, partial [Staphylococcus aureus].	33.85	257	149	8	3	244	4	254	2e-24	114
rs:WP_013451230	DNA topoisomerase I [Calditerrivibrio nitroreducens].	25.69	580	366	18	93	640	70	616	2e-24	119
tr:A0A0E0M300_ORYPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OPUNC09G13790.1};	23.55	620	399	23	3	586	6	586	2e-24	119
rs:WP_002358513	toprim domain protein, partial [Enterococcus faecium].	31.84	223	143	5	3	217	4	225	2e-24	114
rs:WP_008646106	hypothetical protein, partial [Bacteroides sp. 1_1_30].	28.06	335	223	10	349	676	34	357	2e-24	116
rs:WP_035627404	DNA topoisomerase III, partial [Herminiimonas sp. CN].	33.19	235	130	7	3	223	5	226	2e-24	114
rs:WP_036178576	hypothetical protein, partial [Lysinibacillus massiliensis].	27.59	319	220	6	338	654	39	348	2e-24	115
rs:WP_031573190	DNA topoisomerase I [Streptococcus parasanguinis].	25.69	576	361	23	83	629	69	606	2e-24	119
rs:WP_042905719	DNA topoisomerase I [Haemophilus parasuis].	25.25	606	371	21	60	633	87	642	2e-24	119
rs:WP_033795207	DNA topoisomerase, partial [Enterococcus faecium].	31.84	223	143	5	3	217	4	225	2e-24	114
tr:C9CG38_ENTFC	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEV43554.1};	26.27	335	228	7	351	667	1	334	2e-24	115
tr:C9CGT7_ENTFC	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEV43808.1}; Flags: Fragment;	31.84	223	143	5	3	217	5	226	2e-24	114
rs:WP_003632876	DNA topoisomerase I [Legionella longbeachae].	25.32	628	380	28	55	630	29	619	2e-24	119
rs:WP_035496414	DNA topoisomerase I [Haemophilus parasuis].	25.17	604	370	21	60	631	87	640	2e-24	119
rs:WP_031881006	DNA topoisomerase III, partial [Staphylococcus aureus].	33.85	257	149	8	3	244	4	254	2e-24	114
rs:WP_008321710	DNA topoisomerase I [Haloferax mucosum].	22.82	723	442	27	2	661	6	675	2e-24	119
rs:WP_031923562	DNA topoisomerase III, partial [Staphylococcus aureus].	26.53	343	236	6	284	620	3	335	2e-24	116
rs:WP_041741519	DNA topoisomerase I [Caldicellulosiruptor kronotskyensis].	25.26	578	369	15	83	629	60	605	2e-24	119
rs:WP_023918171	DNA topoisomerase 1 [Streptococcus parasanguinis].	25.69	576	361	23	83	629	69	606	2e-24	119
rs:WP_003454290	DNA topoisomerase I [Pseudomonas pseudoalcaligenes].	24.87	591	368	20	90	646	77	625	2e-24	119
rs:WP_013903584	DNA topoisomerase I [Streptococcus parasanguinis].	25.69	576	361	23	83	629	71	608	2e-24	119
rs:WP_021118814	DNA topoisomerase I [Haemophilus parasuis].	25.25	606	371	21	60	633	87	642	2e-24	119
rs:WP_002354343	DNA topoisomerase, partial [Enterococcus faecium].	26.89	331	223	7	355	667	2	331	2e-24	115
rs:WP_004064987	DNA topoisomerase I [Haloferax lucentense].	23.11	727	435	28	2	661	6	675	2e-24	119
rs:WP_032819641	topoisomerase I, partial [Oenococcus oeni].	28.21	319	201	8	189	489	3	311	2e-24	115
rs:WP_036757601	DNA topoisomerase I [Peptoniphilus lacrimalis].	25.00	576	365	21	83	629	71	608	2e-24	119
rs:WP_036875017	hypothetical protein, partial [Prevotella nigrescens].	27.73	375	245	11	309	673	1	359	2e-24	115
rs:WP_004836449	DNA topoisomerase I [Anaerococcus tetradius].	26.36	660	357	30	3	616	5	581	2e-24	118
rs:WP_004057583	DNA topoisomerase I [Haloferax mediterranei].	23.60	733	424	30	2	661	6	675	2e-24	119
rs:WP_035146261	DNA topoisomerase III, partial [Lactobacillus sakei].	33.48	221	137	5	2	219	4	217	2e-24	113
rs:WP_006905958	DNA topoisomerase III [Shuttleworthia satelles].	32.19	233	136	7	3	219	5	231	3e-24	119
rs:WP_006905958	DNA topoisomerase III [Shuttleworthia satelles].	24.46	368	228	9	261	579	354	720	3e-18	99.8
tr:E4SE67_CALK2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.26	578	369	15	83	629	59	604	3e-24	118
rs:WP_004077426	DNA topoisomerase I [Methanoplanus limicola].	23.23	594	391	20	46	616	48	599	3e-24	119
rs:WP_027330922	DNA topoisomerase I [Marinimicrobium agarilyticum].	25.51	592	362	20	75	629	90	639	3e-24	119
rs:WP_033185381	DNA topoisomerase I [Pseudoalteromonas sp. PLSV].	24.84	624	350	23	65	629	75	638	3e-24	119
rs:WP_022509891	DNA topoisomerase [Clostridium sp. CAG:609].	24.32	666	391	25	3	629	4	595	3e-24	118
rs:WP_002305038	type I topoisomerase, partial [Enterococcus faecium].	26.84	339	229	7	347	667	21	358	3e-24	115
tr:U7RYE7_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.15	373	227	12	154	498	1	360	3e-24	115
rs:XP_006492984	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X3 [Citrus sinensis].	23.43	683	418	25	3	631	7	638	3e-24	119
rs:WP_004044253	MULTISPECIES: DNA topoisomerase I [Haloferax].	23.11	727	435	28	2	661	6	675	3e-24	119
rs:WP_040080846	DNA topoisomerase I [Mannheimia haemolytica].	25.25	590	371	21	74	631	87	638	3e-24	119
rs:WP_029675922	DNA topoisomerase, partial [Enterococcus faecalis].	26.30	327	214	7	295	603	1	318	3e-24	114
rs:WP_035588535	DNA topoisomerase I [Hippea jasoniae].	25.04	667	393	23	1	629	1	598	3e-24	118
rs:WP_020448704	DNA topoisomerase I [Candidatus Methanomassiliicoccus intestinalis].	24.78	577	356	21	87	630	89	620	3e-24	119
rs:WP_040638147	DNA topoisomerase, partial [Microvirga lotononidis].	24.44	540	328	20	44	521	27	548	3e-24	117
rs:WP_037503922	DNA topoisomerase I, partial [Sphingomonas jaspsi].	24.17	720	434	29	1	676	1	652	3e-24	118
tr:A0A0A0WVM8_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.57	399	249	12	299	673	13	395	3e-24	117
rs:WP_038060592	hypothetical protein, partial [Thermodesulfobacterium commune].	27.30	575	341	19	2	557	4	520	3e-24	117
rs:WP_004222574	hypothetical protein [Bifidobacterium pseudocatenulatum].	24.80	383	225	9	351	679	1	374	3e-24	115
rs:WP_028027328	DNA topoisomerase [Enterorhabdus mucosicola].	24.22	578	333	19	90	616	135	658	3e-24	118
rs:WP_029656511	DNA topoisomerase, partial [Enterococcus faecalis].	26.79	321	208	7	293	595	84	395	3e-24	115
rs:WP_044960776	DNA topoisomerase III [Shuttleworthia sp. MSX8B].	32.19	233	136	7	3	219	5	231	3e-24	118
rs:WP_044960776	DNA topoisomerase III [Shuttleworthia sp. MSX8B].	23.85	369	230	9	261	579	354	721	2e-18	100
rs:WP_045759471	DNA topoisomerase I [Streptococcus parasanguinis].	25.00	576	365	21	83	629	69	606	3e-24	118
rs:XP_004296978	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Fragaria vesca subsp. vesca].	23.05	668	438	21	3	631	7	637	4e-24	118
rs:WP_009322477	DNA topoisomerase I [Subdoligranulum sp. 4_3_54A2FAA].	24.16	567	365	16	83	616	59	593	4e-24	118
rs:WP_014713336	DNA topoisomerase I [Streptococcus parasanguinis].	25.69	576	361	23	83	629	71	608	4e-24	118
rs:XP_010650401	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Vitis vinifera].	23.22	676	430	23	3	631	10	643	4e-24	118
rs:WP_005581320	DNA topoisomerase I [Natronobacterium gregoryi].	22.97	727	435	29	1	661	1	668	4e-24	118
rs:WP_007697630	DNA topoisomerase I [Halovivax asiaticus].	22.31	726	444	29	1	661	1	671	4e-24	118
rs:WP_041738085	DNA topoisomerase I [Caldicellulosiruptor owensensis].	24.83	580	369	17	83	629	60	605	4e-24	118
tr:W0E1F8_MARPU	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:AHF04680.1};	27.24	279	195	4	343	614	10	287	4e-24	114
rs:WP_007144187	DNA topoisomerase I [Methylophaga aminisulfidivorans].	24.64	625	392	23	76	656	53	642	4e-24	118
rs:WP_038051617	DNA topoisomerase I [Thermotoga sp. Mc24].	26.46	650	354	25	2	616	7	567	4e-24	117
rs:WP_002817879	hypothetical protein, partial [Campylobacter coli].	32.77	238	134	7	1	224	1	226	4e-24	112
rs:WP_016328687	DNA topoisomerase I [Thermus oshimai].	25.76	625	364	25	32	616	33	597	4e-24	118
rs:WP_012799454	DNA topoisomerase [Slackia heliotrinireducens].	24.09	718	411	27	1	631	1	671	4e-24	118
rs:WP_008092043	DNA topoisomerase I [Haloferax prahovense].	23.25	727	434	29	2	661	6	675	4e-24	118
rs:XP_001024996	DNA topoisomerase I [Tetrahymena thermophila SB210].	24.55	607	388	20	3	572	9	582	4e-24	118
rs:WP_031796200	DNA topoisomerase III, partial [Staphylococcus aureus].	28.49	344	231	6	219	555	20	355	4e-24	114
tr:T1ZVG8_STRAP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AGU81557.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AGU81557.1};	25.88	541	343	17	59	576	7	512	4e-24	116
rs:WP_016465755	DNA topoisomerase 1 [Streptococcus sp. HPH0090].	24.83	576	366	21	83	629	71	608	4e-24	117
tr:E4Q5B6_CALOW	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.83	580	369	17	83	629	59	604	4e-24	117
rs:WP_015286106	topoisomerase IA [Methanoregula formicica].	24.21	661	395	26	1	616	1	600	4e-24	118
rs:WP_032825177	topoisomerase I, partial [Oenococcus oeni].	28.21	319	201	8	189	489	3	311	4e-24	114
tr:U2ITY5_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERJ70975.1};	27.13	387	232	12	309	673	3	361	4e-24	115
tr:K1YKP6_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EKD37696.1}; Flags: Fragment;	35.65	216	117	7	3	204	6	213	4e-24	111
rs:WP_005039100	DNA topoisomerase I [Halococcus salifodinae].	23.19	664	406	28	1	616	1	608	4e-24	118
rs:WP_044531589	DNA topoisomerase III, partial [Herbaspirillum sp. B65].	34.56	217	115	7	3	205	5	208	4e-24	111
rs:WP_036859382	DNA topoisomerase I, partial [Prevotella disiens].	27.98	386	230	13	309	673	1	359	5e-24	115
tr:A0A0D8IZI5_9FIRM	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJF39904.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KJF39904.1};	24.16	567	365	16	83	616	59	593	5e-24	117
rs:WP_031234877	DNA topoisomerase III, partial [Salmonella enterica].	24.77	323	220	6	276	578	2	321	5e-24	114
rs:WP_006251055	topoisomerase I [Mannheimia haemolytica].	25.25	590	371	21	74	631	87	638	5e-24	118
rs:WP_027437844	DNA topoisomerase I [Lachnospira multipara].	25.18	564	358	16	83	616	60	589	5e-24	117
rs:WP_002352634	toprim domain protein, partial [Enterococcus faecium].	31.39	223	144	5	3	217	4	225	5e-24	113
rs:WP_021118106	DNA topoisomerase I [Haemophilus parasuis].	25.48	471	296	13	187	631	199	640	5e-24	118
rs:WP_013458656	DNA topoisomerase I [Oceanithermus profundus].	25.60	582	342	21	90	630	68	599	5e-24	118
tr:V8CP57_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETD29168.1};	27.93	333	219	9	351	673	1	322	5e-24	114
rs:WP_008441419	DNA topoisomerase I, archaeal [Thermoplasmatales archaeon SCGC AB-539-N05].	25.37	670	408	31	1	629	1	619	5e-24	117
rs:WP_045168977	DNA topoisomerase I [Caldicellulosiruptor sp. Rt8.B8].	25.47	589	355	20	83	629	59	605	5e-24	117
rs:WP_006056449	DNA topoisomerase I [Halogeometricum borinquense].	22.95	719	442	28	2	661	6	671	5e-24	118
rs:WP_010547138	topoisomerase I [gamma proteobacterium HIMB30].	23.08	598	382	17	72	633	72	627	5e-24	118
rs:WP_041434247	DNA topoisomerase I [Thermocrinis albus].	25.90	498	313	13	83	564	57	514	5e-24	116
rs:XP_007034151	DNA topoisomerase, type IA, core [Theobroma cacao].	24.60	622	390	24	3	586	8	588	5e-24	118
rs:WP_031556695	DNA topoisomerase I [Lachnospira multipara].	25.18	564	358	16	83	616	60	589	5e-24	117
rs:WP_036869928	DNA topoisomerase I, partial [Prevotella disiens].	27.13	387	232	12	309	673	8	366	5e-24	114
rs:WP_035435739	DNA topoisomerase [Atopobium sp. BS2].	25.63	593	356	28	58	615	110	652	5e-24	118
rs:WP_022407582	DNA topoisomerase [Bacillus sp. CAG:988].	24.81	657	401	24	2	629	4	596	5e-24	117
rs:WP_022679588	DNA topoisomerase I [Sandarakinorhabdus limnophila].	24.45	683	399	28	1	629	1	620	5e-24	118
tr:A0A090RXB4_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.32	266	160	8	244	493	39	292	5e-24	113
tr:U2DY69_9BACE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERI84806.1};	27.16	335	224	11	347	676	31	350	5e-24	114
rs:WP_006302460	DNA topoisomerase [Atopobium vaginae].	23.60	712	417	25	1	629	1	668	5e-24	118
rs:WP_043763722	DNA topoisomerase, partial [Marichromatium purpuratum].	27.54	276	192	4	346	614	2	276	5e-24	114
rs:WP_014555165	DNA topoisomerase I [Haloquadratum walsbyi].	23.34	737	429	30	2	661	6	683	5e-24	118
tr:D3SM80_THEAH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00003390}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.90	498	313	13	83	564	58	515	5e-24	116
rs:WP_032821592	topoisomerase I, partial [Oenococcus oeni].	33.91	230	142	6	3	223	4	232	6e-24	112
rs:WP_043061269	DNA topoisomerase I [Sphingomonas taxi].	23.05	668	421	23	1	629	1	614	6e-24	117
rs:WP_010891344	hypothetical protein, partial [Streptococcus agalactiae].	27.12	295	206	4	374	660	1	294	6e-24	113
rs:WP_043951872	DNA topoisomerase, partial [Enterococcus faecium].	31.94	216	138	5	3	210	34	248	6e-24	112
rs:NP_001254381	Y48C3A.14, isoform a [Caenorhabditis elegans].	24.29	638	381	25	3	585	6	596	6e-24	117
rs:WP_004463162	DNA topoisomerase I [Ruminiclostridium thermocellum].	25.29	613	389	20	90	671	67	641	6e-24	117
rs:WP_040216033	DNA topoisomerase I [Haemophilus parahaemolyticus].	24.92	590	373	18	74	631	87	638	6e-24	117
rs:WP_019550692	DNA topoisomerase I [Thermus scotoductus].	24.66	669	376	27	3	616	19	614	6e-24	117
rs:WP_028893704	hypothetical protein [Syntrophorhabdus aromaticivorans].	24.73	655	401	25	55	667	29	633	6e-24	117
rs:WP_006249032	topoisomerase I [Mannheimia haemolytica].	25.25	590	371	21	74	631	87	638	6e-24	117
rs:WP_004972896	DNA topoisomerase I [Haloferax gibbonsii].	23.25	727	434	29	2	661	6	675	6e-24	117
tr:K1S1X7_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EKC54717.1};	25.19	663	389	24	3	629	5	596	6e-24	117
rs:WP_016103249	DNA topoisomerase 3 [Bacillus cereus].	36.04	197	110	8	3	193	5	191	6e-24	110
rs:WP_023499727	Topoisomerase IA [uncultured archaeon A07HB70].	22.96	723	442	30	1	661	1	670	6e-24	117
rs:WP_022416141	DNA topoisomerase [Dorea longicatena CAG:42].	24.51	412	263	11	224	594	59	463	6e-24	115
rs:WP_033615628	DNA topoisomerase, partial [Enterococcus faecium].	26.56	320	211	7	293	597	84	394	6e-24	114
rs:WP_013291224	DNA topoisomerase I [Caldicellulosiruptor obsidiansis].	25.17	580	367	17	83	629	59	604	7e-24	117
rs:WP_025342644	DNA topoisomerase I [Mannheimia varigena].	25.13	589	373	20	74	631	87	638	7e-24	117
rs:WP_036239280	DNA topoisomerase I [Marinospirillum insulare].	25.21	591	370	18	76	633	83	634	7e-24	117
rs:WP_003014956	DNA topoisomerase I [Streptococcus parasanguinis].	25.52	576	362	23	83	629	71	608	7e-24	117
rs:WP_027835164	DNA topoisomerase I [Maritalea myrionectae].	24.76	626	378	23	1	592	1	567	7e-24	117
rs:WP_026234060	DNA topoisomerase I [Thermus oshimai].	25.76	625	364	25	32	616	33	597	7e-24	117
rs:WP_022257719	DNA topoisomerase [Faecalibacterium sp. CAG:82].	25.26	665	403	23	2	630	3	609	7e-24	117
rs:WP_002349115	toprim domain protein, partial [Enterococcus faecium].	31.39	223	144	5	3	217	4	225	7e-24	111
rs:WP_029657060	DNA topoisomerase, partial [Enterococcus faecalis].	26.79	321	208	7	293	595	84	395	7e-24	114
rs:WP_008153390	hypothetical protein, partial [Parabacteroides johnsonii].	27.71	350	226	11	174	511	1	335	7e-24	114
rs:WP_002349701	toprim domain protein, partial [Enterococcus faecium].	32.41	216	137	5	3	210	4	218	7e-24	111
rs:WP_029712355	hypothetical protein, partial [BRC1 bacterium SCGC AAA257-C11].	25.41	606	354	20	82	630	61	625	7e-24	117
rs:WP_036311140	DNA topoisomerase I [Methylophaga thiooxydans].	24.96	705	413	34	2	656	4	642	7e-24	117
rs:WP_045411980	DNA topoisomerase I [Thermoanaerobacterium saccharolyticum].	25.77	555	350	14	90	616	67	587	7e-24	117
rs:WP_016201111	DNA topoisomerase I [Bacillus nealsonii].	25.58	563	342	22	105	629	83	606	7e-24	117
rs:WP_025247671	DNA topoisomerase I [Mannheimia varigena].	25.13	589	373	20	74	631	87	638	7e-24	117
rs:WP_011570557	DNA topoisomerase I [Haloquadratum walsbyi].	22.72	735	436	28	2	661	6	683	7e-24	117
rs:WP_002295954	type I topoisomerase, partial [Enterococcus faecium].	30.12	249	158	4	443	675	3	251	8e-24	112
rs:WP_032907384	DNA topoisomerase I [Streptococcus sanguinis].	25.09	578	362	21	83	629	70	607	8e-24	117
rs:WP_043888070	DNA topoisomerase I [Methylophaga thiooxydans].	24.96	705	413	34	2	656	4	642	8e-24	117
tr:F0FDB0_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.57	575	363	21	83	629	73	610	8e-24	117
rs:WP_032913392	DNA topoisomerase I [Streptococcus sanguinis].	25.09	578	362	21	83	629	70	607	8e-24	117
tr:A0A0D6JSG2_9EURY	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:CQR50836.1};	22.87	726	438	27	2	661	6	675	8e-24	117
tr:A0A0B7GQ73_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.09	578	362	21	83	629	70	607	8e-24	117
rs:WP_032908166	DNA topoisomerase I [Streptococcus sanguinis].	25.04	579	361	21	83	629	70	607	8e-24	117
tr:K1RZ42_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC48414.1}; Flags: Fragment;	29.34	317	199	8	374	673	11	319	8e-24	113
rs:WP_011972751	DNA topoisomerase I [Methanococcus aeolicus].	25.71	595	371	22	3	566	4	558	8e-24	117
rs:WP_033620255	DNA topoisomerase, partial [Enterococcus faecalis].	30.12	249	158	4	443	675	7	255	8e-24	112
tr:C0N5G6_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.96	705	413	34	2	656	17	655	8e-24	117
rs:WP_005614950	topoisomerase I [Actinobacillus pleuropneumoniae].	24.28	593	373	17	74	631	88	639	8e-24	117
rs:WP_004970153	DNA topoisomerase I [Haloferax denitrificans].	23.25	727	434	29	2	661	6	675	8e-24	117
rs:WP_012939689	DNA topoisomerase I [Archaeoglobus profundus].	25.07	694	418	26	1	652	1	634	8e-24	117
rs:WP_032914166	DNA topoisomerase I [Streptococcus sanguinis].	25.57	575	363	21	83	629	70	607	8e-24	117
rs:WP_032906559	DNA topoisomerase I [Streptococcus sanguinis].	25.57	575	363	21	83	629	70	607	9e-24	117
rs:XP_012078427	PREDICTED: DNA topoisomerase 3-beta [Jatropha curcas].	23.25	671	434	25	3	631	7	638	9e-24	117
tr:A0A0B3AS91_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.21	599	333	23	3	560	111	641	9e-24	117
rs:WP_032910423	DNA topoisomerase I [Streptococcus sanguinis].	25.09	578	362	21	83	629	70	607	9e-24	117
tr:F9E0C3_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.04	579	361	21	83	629	73	610	9e-24	117
tr:E2XSJ8_PSEFL	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFQ63312.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFQ63312.1};	25.17	302	205	6	348	638	3	294	9e-24	112
rs:WP_022283279	DNA topoisomerase [Clostridium sp. CAG:417].	25.04	663	390	24	3	629	5	596	9e-24	117
rs:WP_032914840	DNA topoisomerase I [Streptococcus sanguinis].	25.57	575	363	21	83	629	70	607	9e-24	117
tr:F0IUZ5_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.09	578	362	21	83	629	73	610	9e-24	117
tr:F0FTK4_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.09	578	362	21	83	629	73	610	9e-24	117
tr:F2CD39_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.09	578	362	21	83	629	73	610	9e-24	117
rs:WP_032909544	DNA topoisomerase I [Streptococcus sanguinis].	25.09	578	362	21	83	629	70	607	9e-24	117
rs:WP_032908811	DNA topoisomerase I [Streptococcus sanguinis].	25.09	578	362	21	83	629	70	607	9e-24	117
tr:E4S8P0_CALKI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.70	579	371	16	83	629	59	604	9e-24	117
tr:F3UXP6_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.09	578	362	21	83	629	73	610	9e-24	117
rs:WP_013194169	DNA topoisomerase I [Methanohalobium evestigatum].	23.94	660	433	25	1	629	1	622	9e-24	117
rs:WP_015300379	topoisomerase IA [Halovivax ruber].	22.22	720	452	27	1	661	23	693	1e-23	117
rs:WP_022226467	DNA topoisomerase [Clostridium sp. CAG:302].	24.64	702	440	26	2	678	4	641	1e-23	116
tr:W0JX63_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.71	722	440	29	1	661	1	665	1e-23	117
rs:WP_006825523	DNA topoisomerase I [Natrialba taiwanensis].	22.45	717	450	26	1	661	1	667	1e-23	117
rs:WP_015718165	DNA topoisomerase I [Thermus scotoductus].	25.21	595	342	23	77	616	49	595	1e-23	117
rs:WP_035426888	DNA topoisomerase [Atopobium sp. ICM42b].	25.46	593	357	28	58	615	110	652	1e-23	117
rs:WP_046140197	DNA topoisomerase I [Devosia insulae].	23.30	691	403	24	1	630	1	625	1e-23	117
rs:WP_031514382	DNA topoisomerase I, partial [Desulfotomaculum alkaliphilum].	25.53	568	348	20	88	616	63	594	1e-23	117
rs:WP_032576998	DNA topoisomerase I, partial [Bacteroides fragilis].	30.17	242	149	6	1	229	1	235	1e-23	112
rs:WP_043951828	DNA topoisomerase, partial [Enterococcus faecium].	31.94	216	138	5	3	210	34	248	1e-23	111
rs:WP_042700233	DNA topoisomerase I [Methanocorpusculum bavaricum].	24.27	684	399	29	1	630	1	619	1e-23	117
rs:WP_003007403	DNA topoisomerase I [Streptococcus parasanguinis].	25.52	576	362	23	83	629	69	606	1e-23	116
rs:WP_013931564	DNA topoisomerase I [Pseudothermotoga thermarum].	25.66	565	356	16	55	592	29	556	1e-23	116
tr:F3USB2_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.57	575	363	21	83	629	73	610	1e-23	116
rs:WP_035168545	MULTISPECIES: DNA topoisomerase I [Caldicellulosiruptor].	24.70	579	371	16	83	629	60	605	1e-23	116
rs:WP_045497387	DNA topoisomerase I [Streptococcus cristatus].	25.09	578	362	21	83	629	70	607	1e-23	116
rs:WP_045175688	DNA topoisomerase I [Caldicellulosiruptor sp. Wai35.B1].	25.09	578	370	15	83	629	60	605	1e-23	116
rs:WP_008813642	MULTISPECIES: topoisomerase I [Hafnia].	25.54	599	363	19	74	633	80	634	1e-23	117
rs:WP_021674657	DNA topoisomerase, partial [Peptostreptococcaceae bacterium oral taxon 113].	32.21	298	176	7	192	482	1	279	1e-23	112
tr:E8KPH4_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.57	575	363	21	83	629	73	610	1e-23	116
tr:F9DSM1_9BACL	SubName: Full=Conjugal transfer nickase/helicase TraI {ECO:0000313|EMBL:EGQ26195.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EGQ26195.1};	28.12	345	223	12	349	673	26	365	1e-23	114
rs:XP_001636325	predicted protein [Nematostella vectensis].	24.56	680	421	24	3	631	5	643	1e-23	117
tr:J6QSP7_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EJX60598.1}; Flags: Fragment;	31.94	216	138	5	3	210	4	218	1e-23	110
rs:WP_015604970	DNA topoisomerase I [Streptococcus oligofermentans].	25.09	578	362	21	83	629	70	607	1e-23	116
rs:WP_016523533	DNA topoisomerase I [Treponema medium].	24.92	658	381	25	3	618	14	600	1e-23	116
rs:WP_035305590	DNA topoisomerase, partial [Clostridium sp. HMP27].	26.27	434	279	14	271	675	17	438	1e-23	114
rs:WP_046143534	DNA topoisomerase I [Devosia soli].	22.64	689	408	21	1	629	1	624	1e-23	117
rs:WP_011575153	topoisomerase I [Pseudoalteromonas atlantica].	24.84	624	350	23	65	629	75	638	1e-23	117
rs:WP_015319853	DNA topoisomerase I [Natronococcus occultus].	22.81	719	446	28	1	661	1	668	1e-23	117
tr:G9YAG8_HAFAL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.54	599	363	19	74	633	121	675	1e-23	117
rs:WP_006145648	DNA topoisomerase I [Streptococcus peroris].	25.30	577	362	21	83	629	71	608	1e-23	116
tr:A0A0B3B3K1_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.01	604	388	20	61	631	6	571	1e-23	116
tr:G2PUY5_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.70	579	371	16	83	629	59	604	1e-23	116
rs:WP_040759101	DNA topoisomerase III, partial [Sporosarcina newyorkensis].	28.12	345	223	12	349	673	40	379	1e-23	113
rs:WP_011839553	DNA topoisomerase I [Staphylothermus marinus].	25.32	553	343	20	68	587	115	630	1e-23	116
rs:WP_009754430	DNA topoisomerase I [Streptococcus sp. oral taxon 056].	24.91	578	363	21	83	629	70	607	1e-23	116
rs:WP_006990851	DNA topoisomerase I [Glaciecola mesophila].	25.12	617	357	23	65	629	75	638	1e-23	116
rs:WP_010916276	DNA topoisomerase I [Thermoplasma volcanium].	26.03	557	351	21	46	585	55	567	1e-23	116
tr:W0RS27_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.11	610	349	20	3	561	12	552	1e-23	116
tr:M5AIA3_LACBR	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:BAN08120.1};	33.91	230	142	6	3	223	4	232	1e-23	112
rs:WP_027726063	DNA topoisomerase I [Tuberibacillus calidus].	25.88	568	352	22	103	635	80	613	1e-23	116
rs:WP_041725675	DNA topoisomerase I [Caldicellulosiruptor lactoaceticus].	24.70	579	371	16	83	629	60	605	1e-23	116
tr:A0A061HTE1_CRIGR	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:ERE48419.1}; EC=5.99.1.2 {ECO:0000313|EMBL:ERE48419.1}; Flags: Fragment;	28.71	303	174	9	3	263	8	310	1e-23	112
rs:WP_006169072	DNA topoisomerase I [Natrialba chahannaoensis].	22.39	719	448	27	1	661	1	667	1e-23	116
tr:T0N6P8_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.21	419	270	9	292	676	12	429	1e-23	114
rs:WP_020564824	DNA topoisomerase I [Methylosarcina fibrata].	23.78	694	424	27	3	649	5	640	2e-23	116
rs:WP_005591982	DNA topoisomerase I [Streptococcus cristatus].	24.91	578	363	21	83	629	70	607	2e-23	116
rs:WP_027954195	DNA topoisomerase I [Halobacillus kuroshimensis].	25.97	566	350	22	105	635	82	613	2e-23	116
rs:WP_006148622	DNA topoisomerase I [Streptococcus infantis].	24.83	580	361	23	83	629	71	608	2e-23	116
tr:X3PRR7_SALEN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.17	242	158	7	245	479	18	255	2e-23	111
tr:E8JTB1_STRCR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.91	578	363	21	83	629	73	610	2e-23	116
tr:R3VF15_ENTFL	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOL33831.1};	32.44	225	136	4	467	675	11	235	2e-23	110
rs:WP_032912913	DNA topoisomerase I [Streptococcus sanguinis].	25.09	578	362	21	83	629	70	607	2e-23	115
rs:WP_038041147	DNA topoisomerase I [Thermus yunnanensis].	25.47	585	340	23	77	616	76	609	2e-23	116
rs:WP_011310523	DNA topoisomerase I [Thiobacillus denitrificans].	23.61	648	375	26	36	630	21	601	2e-23	116
rs:WP_004049062	DNA topoisomerase I [Halorubrum saccharovorum].	23.32	742	444	30	2	661	6	704	2e-23	116
rs:WP_044345975	DNA topoisomerase III, partial [Pseudomonas meliae].	31.93	285	178	6	157	425	33	317	2e-23	112
rs:WP_033195612	DNA topoisomerase I, partial [Kushneria aurantia].	23.33	600	368	17	76	633	94	643	2e-23	116
rs:WP_021153232	DNA topoisomerase I [Streptococcus sp. HSISM1].	25.52	576	362	23	83	629	69	606	2e-23	115
tr:F5W1Z7_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.83	576	366	21	83	629	24	561	2e-23	115
rs:WP_029659198	DNA topoisomerase, partial [Enterococcus faecalis].	32.44	225	136	4	467	675	8	232	2e-23	110
rs:WP_002350831	toprim domain protein, partial [Enterococcus faecium].	31.94	216	138	5	3	210	4	218	2e-23	110
rs:WP_041723101	DNA topoisomerase I [Caldicellulosiruptor hydrothermalis].	24.87	579	370	16	83	629	60	605	2e-23	115
tr:A5IKG3_THEP1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00003390}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.15	650	356	25	2	616	7	567	2e-23	115
rs:WP_003349030	DNA topoisomerase I [Bacillus methanolicus].	25.22	563	358	23	105	635	82	613	2e-23	115
tr:A0A090KU15_STRRB	SubName: Full=DNA topoisomerase 3-beta {ECO:0000313|EMBL:CEF61010.1};	25.12	629	377	25	3	577	6	594	2e-23	115
rs:XP_002516387	prokaryotic DNA topoisomerase, putative [Ricinus communis].	22.87	669	439	23	3	631	7	638	2e-23	116
rs:WP_009660457	DNA topoisomerase I [Streptococcus sp. AS14].	24.91	578	363	21	83	629	70	607	2e-23	115
rs:WP_016519476	DNA topoisomerase I [Treponema vincentii].	24.81	653	378	25	3	615	18	597	2e-23	115
rs:WP_045121537	DNA topoisomerase, partial [Fusobacterium nucleatum].	29.44	394	241	15	53	429	11	384	2e-23	113
rs:WP_012896210	DNA topoisomerase I [Thermotoga naphthophila].	26.15	650	356	25	2	616	7	567	2e-23	115
tr:E4QCU7_CALH1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.87	579	370	16	83	629	59	604	2e-23	115
rs:WP_005935543	DNA topoisomerase I [Faecalibacterium prausnitzii].	25.68	662	404	23	2	630	3	609	2e-23	115
tr:H1HI78_FUSNU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHO75743.1}; Flags: Fragment;	29.44	394	241	15	53	429	11	384	2e-23	113
tr:Q702B0_9CREN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.65	620	372	22	2	578	13	586	2e-23	115
rs:WP_016170258	hypothetical protein [Parcubacteria bacterium SCGC AAA011-G05].	25.74	676	386	27	1	629	1	607	2e-23	115
rs:WP_042630907	DNA topoisomerase III, partial [Escherichia coli].	27.76	389	231	14	293	646	3	376	2e-23	114
rs:WP_025217263	DNA topoisomerase I [Mannheimia varigena].	24.96	589	374	20	74	631	87	638	2e-23	116
tr:F3SHN7_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.09	578	362	21	83	629	73	610	2e-23	115
rs:WP_028962263	DNA topoisomerase I [Sulfobacillus thermosulfidooxidans].	25.85	588	350	25	90	630	69	617	2e-23	115
rs:XP_003538536	PREDICTED: DNA topoisomerase 3-beta-1-like [Glycine max].	22.74	664	442	21	3	631	9	636	2e-23	116
rs:WP_008697687	DNA topoisomerase I [Fusobacterium ulcerans].	26.87	547	330	19	90	607	68	573	2e-23	115
rs:WP_038058400	DNA topoisomerase I [Thermus sp. YIM 77409].	25.59	598	337	20	77	616	76	623	2e-23	116
rs:WP_010418604	DNA topoisomerase I [Leptospira inadai].	23.03	673	408	20	2	630	3	609	2e-23	115
rs:WP_039709081	DNA topoisomerase I [Actinobacillus pleuropneumoniae].	24.41	594	371	19	74	631	88	639	2e-23	116
rs:WP_023394812	DNA topoisomerase I [Candidatus Halobonum tyrrellensis].	22.98	692	396	29	1	618	1	629	2e-23	116
rs:WP_033117512	DNA topoisomerase I [Intestinimonas butyriciproducens].	24.61	581	383	19	90	640	68	623	2e-23	115
rs:WP_018651935	topoisomerase I [Actinobacillus capsulatus].	24.28	593	373	17	74	631	88	639	2e-23	116
rs:WP_005611954	topoisomerase I [Actinobacillus pleuropneumoniae].	24.11	593	374	17	74	631	88	639	2e-23	116
rs:WP_025796836	DNA topoisomerase I [Hafnia alvei].	25.54	599	363	19	74	633	80	634	2e-23	116
rs:WP_038071896	DNA topoisomerase I [Thermus scotoductus].	25.12	605	338	23	77	616	49	603	2e-23	115
rs:WP_040302418	DNA topoisomerase I [Aneurinibacillus aneurinilyticus].	24.35	579	380	22	88	635	62	613	2e-23	115
rs:WP_005600888	topoisomerase I [Actinobacillus pleuropneumoniae].	24.11	593	374	17	74	631	88	639	2e-23	115
rs:WP_029689622	DNA topoisomerase I [Streptococcus infantis].	24.83	576	366	21	83	629	54	591	2e-23	115
rs:WP_021791689	hypothetical protein [Thermoplasmatales archaeon I-plasma].	24.64	556	342	24	89	616	91	597	2e-23	115
rs:WP_013013879	DNA topoisomerase I [Meiothermus ruber].	25.08	666	363	28	3	616	6	587	2e-23	115
rs:WP_003350210	DNA topoisomerase I [Bacillus methanolicus].	26.41	568	345	24	105	635	82	613	2e-23	115
rs:WP_023524932	DNA topoisomerase I [Leptospirillum sp. Group II 'C75'].	24.96	641	381	20	1	616	1	566	2e-23	115
rs:WP_032911974	DNA topoisomerase I [Streptococcus sanguinis].	24.91	578	363	21	83	629	70	607	2e-23	115
rs:WP_020374729	hypothetical protein [Sulfobacillus thermosulfidooxidans].	25.85	588	350	25	90	630	69	617	2e-23	115
rs:WP_005604172	topoisomerase I [Actinobacillus pleuropneumoniae].	24.11	593	374	17	74	631	88	639	2e-23	115
rs:WP_044330152	DNA topoisomerase I [Haemophilus influenzae].	25.79	473	297	13	187	633	196	640	2e-23	115
tr:A0A0D6WXC7_BACIU	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:KIX80101.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIX80101.1};	32.17	230	140	4	462	675	17	246	2e-23	110
rs:WP_019864876	DNA topoisomerase I [Methylovulum miyakonense].	24.23	685	395	29	3	630	5	622	2e-23	115
rs:WP_044015757	DNA topoisomerase I [Treponema sp. OMZ 838].	25.91	575	344	21	83	618	55	586	3e-23	115
rs:WP_002350895	DNA topoisomerase, partial [Enterococcus faecium].	29.88	338	205	8	52	366	3	331	3e-23	112
rs:WP_014991454	topoisomerase I [Actinobacillus suis].	24.28	593	373	17	74	631	88	639	3e-23	115
rs:WP_002351500	DNA topoisomerase, partial [Enterococcus faecium].	27.57	272	185	5	351	611	21	291	3e-23	111
rs:WP_005493764	DNA topoisomerase I [Pseudoalteromonas luteoviolacea].	25.73	614	370	26	60	631	72	641	3e-23	115
rs:WP_046938350	DNA topoisomerase III, partial [Xanthomonas perforans].	27.06	340	229	7	190	511	7	345	3e-23	112
rs:WP_015498061	DNA recombination protein RmuC [Octadecabacter antarcticus].	24.96	597	382	20	3	560	5	574	3e-23	115
rs:WP_032828011	DNA topoisomerase I [Haemophilus haemolyticus].	25.79	473	297	13	187	633	196	640	3e-23	115
rs:WP_038048163	DNA topoisomerase I [Thermus caliditerrae].	24.96	589	338	23	77	616	76	609	3e-23	115
rs:WP_040638921	DNA topoisomerase, partial [Microvirga lotononidis].	24.25	631	395	25	44	609	27	639	3e-23	115
rs:WP_040223245	DNA topoisomerase III, partial [Klebsiella pneumoniae].	29.56	362	227	12	161	496	3	362	3e-23	112
rs:WP_022177538	DNA topoisomerase [Oscillibacter sp. CAG:241].	22.31	614	414	18	90	673	71	651	3e-23	115
rs:WP_006672595	DNA topoisomerase I [Halobiforma nitratireducens].	22.85	731	431	28	1	661	1	668	3e-23	115
tr:U1YAP5_ANEAE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.31	613	404	24	55	635	52	636	3e-23	115
tr:F2BS11_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.91	578	363	21	83	629	73	610	3e-23	115
tr:F9GUB0_HAEHA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.79	473	297	13	187	633	202	646	3e-23	115
rs:WP_010546708	DNA topoisomerase I, partial [Halobiforma lacisalsi].	21.87	718	455	25	1	661	1	669	3e-23	115
rs:WP_036891125	hypothetical protein, partial [Prevotella corporis].	26.93	375	247	11	309	673	1	358	3e-23	112
tr:B9MM33_CALBD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.91	578	371	15	83	629	59	604	3e-23	115
rs:WP_046165540	DNA topoisomerase I [Streptococcus gordonii].	24.57	578	365	21	83	629	70	607	3e-23	115
rs:WP_021040976	Topoisomerase IA [Halonotius sp. J07HN4].	22.18	735	440	29	3	661	7	685	3e-23	115
rs:WP_003517938	DNA topoisomerase I [Ruminiclostridium thermocellum].	25.12	613	390	20	90	671	67	641	3e-23	115
rs:XP_003578369	PREDICTED: DNA topoisomerase 3-beta [Brachypodium distachyon].	23.79	660	413	28	3	614	6	623	3e-23	115
rs:WP_002295723	type I topoisomerase, partial [Enterococcus faecium].	30.12	249	158	4	443	675	3	251	3e-23	110
tr:A0A0A6SU61_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	27.76	389	231	14	293	646	10	383	3e-23	113
rs:WP_012659505	DNA topoisomerase I [Halorubrum lacusprofundi].	23.32	742	444	30	2	661	6	704	3e-23	115
rs:WP_002333469	hypothetical protein, partial [Enterococcus faecium].	29.96	257	163	5	436	675	46	302	3e-23	111
rs:WP_020992625	DNA topoisomerase 1 [Streptococcus sp. 2_1_36FAA].	24.57	578	365	21	83	629	70	607	3e-23	115
rs:WP_022434282	DNA topoisomerase [Mycoplasma sp. CAG:472].	24.70	656	401	22	3	629	4	595	3e-23	115
rs:WP_008119941	topoisomerase IA, partial [Herbaspirillum sp. YR522].	31.91	235	133	7	3	223	5	226	3e-23	110
rs:WP_044998816	hypothetical protein [Roseburia intestinalis].	35.09	171	102	4	1	168	1	165	3e-23	107
rs:WP_042762851	DNA topoisomerase I [Streptococcus sanguinis].	24.74	578	364	21	83	629	70	607	3e-23	115
rs:WP_021792813	hypothetical protein [Thermoplasmatales archaeon E-plasma].	25.65	612	385	21	3	587	5	573	3e-23	115
rs:WP_017471872	DNA topoisomerase I [Amphibacillus jilinensis].	24.82	568	359	22	103	635	80	614	3e-23	115
rs:XP_004957260	PREDICTED: DNA topoisomerase 3-beta [Setaria italica].	23.32	656	421	26	3	614	6	623	4e-23	115
rs:WP_006151577	DNA topoisomerase [Streptococcus infantis].	26.32	494	305	17	40	511	43	499	4e-23	114
rs:WP_037590747	DNA topoisomerase I [Streptococcus hyovaginalis].	24.44	581	363	21	83	629	79	617	4e-23	115
rs:WP_039709549	DNA topoisomerase I [Actinobacillus pleuropneumoniae].	24.41	594	371	19	74	631	88	639	4e-23	115
rs:WP_021996854	DNA topoisomerase [Clostridium sp. CAG:780].	24.11	560	355	19	90	616	67	589	4e-23	115
rs:WP_015492626	Topoisomerase IA [Thermoplasmatales archaeon BRNA1].	23.79	660	399	24	3	618	4	603	4e-23	115
rs:XP_002978156	hypothetical protein SELMODRAFT_233065 [Selaginella moellendorffii].	22.39	652	432	23	3	612	6	625	4e-23	115
tr:F3UAY0_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.74	578	364	21	83	629	73	610	4e-23	114
tr:C7G933_9FIRM	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EEV01684.1};	35.09	171	102	4	1	168	18	182	4e-23	108
rs:WP_041727195	DNA topoisomerase I [Caldicellulosiruptor bescii].	24.91	578	371	15	83	629	60	605	4e-23	114
rs:WP_040980091	DNA topoisomerase I [Oceanobacillus sp. S5].	24.13	576	379	19	90	635	67	614	4e-23	114
rs:WP_042932891	DNA topoisomerase III, partial [Pseudomonas coronafaciens].	29.08	251	162	6	1	242	1	244	4e-23	109
tr:I0TDV4_9BACT	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EID33807.1};	33.97	209	118	6	4	201	5	204	4e-23	108
tr:J3MYW0_ORYBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.88	625	397	25	3	586	6	586	4e-23	115
rs:WP_019935728	topoisomerase I [Oceanimonas smirnovii].	25.38	599	364	22	75	633	87	642	4e-23	115
tr:F2ZR02_9PSED	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGI04855.1}; Flags: Fragment;	29.08	251	162	6	1	242	1	244	4e-23	109
tr:D4K311_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.23	662	407	24	2	630	3	609	4e-23	114
rs:WP_011358785	DNA topoisomerase I [Pelodictyon luteolum].	25.29	613	369	20	76	637	63	637	4e-23	115
sp:TOP3B_ORYSJ	RecName: Full=DNA topoisomerase 3-beta; EC=5.99.1.2;	23.14	618	404	23	3	586	6	586	5e-23	115
rs:WP_041089031	DNA topoisomerase I [Jeotgalibacillus soli Cunha et al. 2012].	26.76	512	301	24	163	635	138	614	5e-23	114
tr:K1SPC5_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central domain protein {ECO:0000313|EMBL:EKC62512.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EKC62512.1}; Flags: Fragment;	30.77	247	158	5	348	587	7	247	5e-23	109
rs:XP_006293663	hypothetical protein CARUB_v10022619mg [Capsella rubella].	23.59	619	400	22	3	586	8	588	5e-23	115
rs:WP_002358501	DNA topoisomerase, partial [Enterococcus faecium].	25.98	331	217	6	290	600	8	330	5e-23	111
rs:WP_005597038	topoisomerase I [Actinobacillus pleuropneumoniae].	24.11	593	374	17	74	631	88	639	5e-23	115
tr:G0MZ90_CAEBE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.44	630	389	25	3	585	550	1139	5e-23	115
rs:WP_039196769	DNA topoisomerase I [Actinobacillus equuli].	24.11	593	374	16	74	631	88	639	5e-23	115
rs:WP_033685170	DNA topoisomerase I [Streptococcus mitis].	24.70	579	363	21	83	629	71	608	5e-23	114
rs:WP_022325316	DNA topoisomerase [Clostridium sp. CAG:798].	25.55	591	353	23	90	636	67	614	5e-23	114
rs:WP_013718626	DNA topoisomerase I [Methanosaeta concilii].	23.72	666	418	29	1	630	1	612	5e-23	114
rs:WP_041844049	DNA topoisomerase I [Thermotoga sp. RQ7].	26.68	641	364	25	2	616	6	566	5e-23	114
rs:WP_035431967	DNA topoisomerase [Atopobium parvulum].	25.46	593	357	28	58	615	110	652	5e-23	114
tr:I1QQ61_ORYGL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.14	618	404	23	3	586	6	586	5e-23	115
rs:WP_036893583	hypothetical protein, partial [Prevotella timonensis].	27.47	375	245	12	309	673	1	358	5e-23	111
rs:WP_033585366	DNA topoisomerase I [Streptococcus sp. SR1].	24.48	580	363	22	83	629	71	608	5e-23	114
rs:WP_027429125	DNA topoisomerase I [Lachnospiraceae bacterium AD3010].	24.48	625	394	23	90	675	67	652	5e-23	114
rs:WP_031534466	DNA topoisomerase I [Bacillus sp. MB2021].	24.82	556	355	19	105	629	82	605	5e-23	114
rs:WP_006365751	DNA topoisomerase I [Chlorobium ferrooxidans].	27.00	611	343	23	76	629	63	627	5e-23	114
rs:WP_036887859	hypothetical protein, partial [Prevotella bivia].	26.67	375	248	11	309	673	1	358	5e-23	111
rs:WP_010530648	DNA topoisomerase I [Lentibacillus jeotgali].	24.36	669	411	26	3	635	5	614	5e-23	114
rs:WP_044071284	hypothetical protein, partial [Prevotella timonensis].	27.47	375	245	12	309	673	1	358	5e-23	111
tr:I4YSH0_9RHIZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.09	660	417	26	16	609	7	648	5e-23	114
rs:WP_039426347	DNA topoisomerase I, partial [Porphyromonas gulae].	35.24	210	116	6	166	368	2	198	5e-23	108
tr:B8BD52_ORYSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.90	620	403	24	3	586	6	586	5e-23	114
rs:WP_027876542	DNA topoisomerase I [Meiothermus cerbereus].	23.98	663	368	25	3	616	6	581	5e-23	115
rs:WP_025064910	DNA topoisomerase, partial [Prevotella disiens].	27.18	379	249	12	309	677	2	363	6e-23	111
rs:WP_011833511	DNA topoisomerase I [Methanocorpusculum labreanum].	23.88	670	419	26	1	630	1	619	6e-23	115
rs:WP_009560096	DNA topoisomerase I [Lactobacillus pasteurii].	26.10	567	337	21	103	629	96	620	6e-23	114
rs:WP_022493747	DNA topoisomerase [Clostridium sp. CAG:628].	27.22	654	386	26	3	629	4	594	6e-23	114
rs:WP_007140501	DNA topoisomerase I [Halobiforma lacisalsi].	22.30	722	447	27	1	661	1	669	6e-23	114
tr:F9PXW2_9STRE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.76	389	247	13	40	408	43	417	6e-23	113
rs:XP_010414048	PREDICTED: DNA topoisomerase 3-beta-like isoform X1 [Camelina sativa].	24.15	621	394	24	3	586	8	588	6e-23	114
rs:WP_013776134	DNA topoisomerase I [Acidianus hospitalis].	28.06	563	307	24	68	587	10	517	6e-23	114
rs:WP_023916231	DNA topoisomerase 1 [Streptococcus sanguinis].	25.22	575	365	21	83	629	70	607	6e-23	114
rs:WP_013753682	topoisomerase I [Glaciecola sp. 4H-3-7+YE-5].	25.04	615	360	22	65	629	75	638	6e-23	114
rs:WP_032911148	DNA topoisomerase I [Streptococcus sanguinis].	25.39	575	364	21	83	629	70	607	6e-23	114
tr:K1SM54_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC48416.1};	38.89	144	71	5	1	137	1	134	7e-23	107
rs:WP_033125859	DNA topoisomerase I [Eubacterium sp. ER2].	24.80	617	386	21	90	671	67	640	7e-23	114
rs:WP_007988003	MULTISPECIES: DNA topoisomerase I [Glaciecola].	25.04	615	360	22	65	629	75	638	7e-23	114
rs:WP_043027054	DNA topoisomerase I [Streptococcus suis].	24.09	577	370	18	83	629	72	610	7e-23	114
rs:WP_013788113	DNA topoisomerase I [Thermoanaerobacterium xylanolyticum].	25.49	557	349	16	90	616	67	587	7e-23	114
tr:A0A0A7GF84_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.70	671	428	27	1	640	1	618	7e-23	114
rs:WP_023387866	DNA topoisomerase I [Youngiibacter fragilis].	26.33	638	362	26	83	671	60	638	7e-23	114
rs:WP_032913578	DNA topoisomerase I [Streptococcus sanguinis].	25.43	578	360	22	83	629	70	607	7e-23	114
rs:WP_011695783	DNA topoisomerase I [Methanosaeta thermophila].	24.10	614	375	24	1	581	1	556	7e-23	114
tr:U7S059_ENTFL	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ERT25498.1}; Flags: Fragment;	31.56	225	138	4	467	675	1	225	7e-23	108
rs:WP_012475813	DNA topoisomerase I [Chlorobium phaeobacteroides].	26.14	681	381	29	3	629	15	627	7e-23	114
rs:WP_023050986	hypothetical protein [Cetobacterium somerae].	25.41	665	385	28	3	629	17	608	7e-23	114
rs:WP_015058240	DNA topoisomerase III [Escherichia coli].	28.20	383	225	15	299	646	2	369	7e-23	112
rs:WP_002404673	toprim domain protein, partial [Enterococcus faecalis].	38.76	178	98	5	50	218	11	186	7e-23	107
rs:WP_019831106	DNA topoisomerase I [Sphingomonas sp. PR090111-T3T-6A].	23.26	675	411	26	1	629	1	614	7e-23	114
rs:WP_046135880	DNA topoisomerase I [Devosia limi].	24.96	689	392	29	1	629	1	624	7e-23	114
rs:WP_002338418	hypothetical protein, partial [Enterococcus faecium].	38.55	179	99	5	49	218	1	177	7e-23	107
rs:WP_032912452	DNA topoisomerase I [Streptococcus sanguinis].	24.74	578	364	21	83	629	70	607	7e-23	114
rs:WP_014586061	DNA topoisomerase I [Methanosaeta harundinacea].	24.10	639	412	26	1	614	1	591	7e-23	114
tr:T0YZJ2_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD37372.1}; Flags: Fragment;	28.76	233	140	5	3	222	136	355	7e-23	110
rs:WP_037443114	DNA topoisomerase I [Shewanella sp. YQH10].	24.69	652	392	25	74	680	88	685	8e-23	114
rs:WP_042594037	DNA topoisomerase I [Haemophilus influenzae].	25.68	475	295	14	187	633	196	640	8e-23	114
rs:WP_013922222	DNA topoisomerase I [Francisella sp. TX077308].	26.45	673	391	28	3	629	5	619	8e-23	114
rs:WP_038074878	DNA topoisomerase I [Thioclava pacifica].	23.93	677	410	24	1	630	1	619	8e-23	114
rs:WP_012809178	DNA topoisomerase [Atopobium parvulum].	24.32	695	403	32	1	615	1	652	8e-23	114
rs:WP_036885247	hypothetical protein, partial [Prevotella disiens].	26.91	379	242	13	309	673	1	358	8e-23	111
rs:WP_022386816	hypothetical protein [Collinsella sp. CAG:289].	23.49	562	353	19	87	616	134	650	8e-23	114
tr:F0IMD6_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.74	578	364	21	83	629	73	610	8e-23	114
rs:WP_011392540	DNA topoisomerase I [Moorella thermoacetica].	24.66	580	365	21	89	630	64	609	8e-23	114
rs:WP_019239215	DNA topoisomerase [Collinsella sp. GD3].	23.38	556	361	19	87	616	133	649	8e-23	114
rs:WP_042599491	DNA topoisomerase I [Haemophilus influenzae].	25.68	475	295	14	187	633	196	640	9e-23	114
rs:WP_040235479	DNA topoisomerase III, partial [Klebsiella pneumoniae].	29.64	334	203	15	1	311	1	325	9e-23	110
tr:F0I228_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.43	578	360	22	83	629	73	610	9e-23	114
tr:A0A0E0E8K2_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OMERI07G04560.1};	23.30	618	403	23	3	586	6	586	9e-23	114
rs:WP_022081022	DNA topoisomerase [Ruminococcus sp. CAG:488].	25.85	588	346	20	76	616	52	596	9e-23	114
tr:A8AXH4_STRGC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.57	578	365	21	83	629	73	610	9e-23	113
rs:XP_002631605	Hypothetical protein CBG20786, partial [Caenorhabditis briggsae].	23.97	630	393	22	3	585	1	591	9e-23	113
tr:K1U9G8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC78843.1}; Flags: Fragment;	29.84	258	167	6	433	683	15	265	9e-23	109
rs:WP_012159330	DNA topoisomerase I [Alkaliphilus oremlandii].	24.48	674	388	27	3	629	5	604	1e-22	113
tr:W1AY89_KLEPN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CDK73336.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDK73336.1};	34.29	210	121	7	1	199	1	204	1e-22	108
rs:WP_041789689	DNA topoisomerase I [Streptococcus gordonii].	24.57	578	365	21	83	629	70	607	1e-22	113
sp:TOP1_AQUAE	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.53	517	338	12	83	589	57	536	1e-22	112
rs:WP_045635329	DNA topoisomerase I [Streptococcus mitis].	24.57	578	365	21	83	629	70	607	1e-22	113
rs:XP_002881210	DNA topoisomerase family protein [Arabidopsis lyrata subsp. lyrata].	23.34	617	404	20	3	586	8	588	1e-22	114
rs:WP_015918923	DNA topoisomerase I [Thermotoga neapolitana].	26.68	641	364	25	2	616	6	566	1e-22	113
tr:L5MMI8_9BACL	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ELK39527.1};	33.04	224	136	7	3	221	5	219	1e-22	108
rs:WP_007641057	topoisomerase I [Cellvibrio sp. BR].	25.25	598	356	23	75	629	90	639	1e-22	114
rs:WP_022028557	DNA topoisomerase [Clostridium sp. CAG:1219].	24.05	661	397	25	3	629	5	594	1e-22	113
tr:A0A096BQP1_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGF44992.1}; Flags: Fragment;	26.65	379	243	13	309	673	15	372	1e-22	110
rs:WP_005622925	topoisomerase I [Actinobacillus ureae].	24.11	593	374	17	74	631	88	639	1e-22	114
rs:WP_038671386	DNA topoisomerase I [Pelosinus sp. UFO1].	25.54	654	378	26	3	616	5	589	1e-22	113
rs:WP_044689880	DNA topoisomerase I [Streptococcus suis].	23.92	577	371	18	83	629	72	610	1e-22	113
rs:WP_024398072	DNA topoisomerase I [Streptococcus suis].	23.92	577	371	18	83	629	72	610	1e-22	113
rs:WP_023938619	DNA topoisomerase I [Streptococcus pseudopneumoniae].	24.70	579	363	20	83	629	71	608	1e-22	113
tr:A0A022R1M4_ERYGU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.02	666	430	25	5	631	8	636	1e-22	113
tr:A0A0B1TGI7_OESDE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.65	503	291	18	95	564	66	518	1e-22	113
rs:WP_031877508	DNA topoisomerase III, partial [Staphylococcus aureus].	33.33	252	147	8	3	239	4	249	1e-22	108
rs:WP_009730244	DNA topoisomerase 1 [Streptococcus sp. F0441].	24.53	579	364	21	83	629	71	608	1e-22	113
rs:WP_009554367	DNA topoisomerase I [Lactobacillus saerimneri].	25.48	573	343	24	103	635	90	618	1e-22	113
rs:XP_012555024	PREDICTED: DNA topoisomerase 3-beta-1-like [Hydra vulgaris].	24.37	599	381	22	3	564	5	568	1e-22	114
rs:WP_045773382	DNA topoisomerase I [Streptococcus sanguinis].	25.04	575	366	21	83	629	70	607	1e-22	113
gpu:CP009501_559	DNA topoisomerase I [Methanosarcina thermophila TM-1]	25.92	463	288	20	188	629	197	625	1e-22	113
tr:W7ASG1_9LIST	SubName: Full=Topoisomerase IA {ECO:0000313|EMBL:EUJ16552.1};	30.99	284	176	8	3	269	4	284	1e-22	109
rs:WP_036885478	DNA topoisomerase I, partial [Prevotella disiens].	28.53	340	217	11	347	673	30	356	1e-22	110
rs:WP_022076495	DNA topoisomerase [Clostridium sp. CAG:571].	24.78	557	354	19	90	616	67	588	1e-22	113
rs:WP_029187270	DNA topoisomerase I [Streptococcus suis].	24.09	577	370	18	83	629	72	610	1e-22	113
rs:WP_002353327	DNA topoisomerase, partial [Enterococcus faecium].	26.02	369	230	7	158	497	23	377	1e-22	110
rs:WP_028256007	DNA topoisomerase I [Veillonella magna].	25.00	580	364	20	83	629	116	657	1e-22	113
rs:WP_005553766	DNA topoisomerase I [Natronococcus amylolyticus].	22.96	723	440	30	1	661	1	668	1e-22	113
rs:WP_025774465	DNA topoisomerase I [Moorella thermoacetica].	24.66	580	365	21	89	630	63	608	1e-22	113
rs:XP_010926664	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Elaeis guineensis].	23.26	619	402	21	3	586	6	586	1e-22	114
tr:W1FC26_ENTCL	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CDL31348.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDL31348.1};	37.35	166	98	3	419	581	29	191	1e-22	107
rs:WP_007288449	DNA topoisomerase I [Thermosinus carboxydivorans].	25.77	652	379	24	3	616	5	589	1e-22	113
tr:T2MI56_HYDVU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.37	599	381	22	3	564	13	576	1e-22	114
tr:G0PNJ8_CAEBE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.86	417	255	14	186	585	12	395	1e-22	113
rs:WP_009222995	DNA topoisomerase I [Paenibacillus sp. oral taxon 786].	25.34	584	372	22	88	636	62	616	1e-22	113
rs:WP_040110015	hypothetical protein, partial [Thalassospira xiamenensis].	24.45	634	367	24	3	560	4	601	1e-22	113
rs:XP_002460479	hypothetical protein SORBIDRAFT_02g029000 [Sorghum bicolor].	24.28	659	409	29	3	614	6	621	1e-22	113
rs:WP_038031619	DNA topoisomerase I [Thermus sp. NMX2.A1].	25.04	595	343	23	77	616	49	595	1e-22	113
rs:WP_000179629	DNA topoisomerase I [Streptococcus mitis].	24.48	580	363	22	83	629	71	608	1e-22	113
rs:WP_044757939	DNA topoisomerase, partial [Streptococcus suis].	27.95	365	222	12	154	490	1	352	1e-22	110
rs:WP_032825615	DNA topoisomerase I [Haemophilus haemolyticus].	25.37	473	299	13	187	633	196	640	1e-22	113
rs:WP_021861600	DNA topoisomerase [Dorea sp. CAG:105].	24.16	567	347	20	90	616	67	590	1e-22	113
rs:WP_008213199	toprim domain protein, partial [Lactobacillus parafarraginis].	33.33	231	144	6	3	224	4	233	1e-22	108
rs:WP_012800727	topoisomerase I [Kangiella koreensis].	25.54	599	360	21	76	633	94	647	1e-22	113
rs:WP_029180300	DNA topoisomerase I [Streptococcus suis].	24.09	577	370	18	83	629	72	610	1e-22	113
rs:WP_027414585	DNA topoisomerase I [Aneurinibacillus terranovensis].	25.22	575	368	19	88	630	62	606	1e-22	113
rs:WP_011836973	DNA topoisomerase I [Streptococcus sanguinis].	25.43	578	360	22	83	629	73	610	1e-22	113
rs:WP_005659512	topoisomerase I [Haemophilus influenzae].	25.68	475	295	14	187	633	196	640	1e-22	113
tr:F9GJ95_HAEHA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.37	473	299	13	187	633	202	646	1e-22	113
rs:WP_022215638	DNA topoisomerase [Blautia sp. CAG:237].	25.47	424	253	16	224	598	34	443	1e-22	111
tr:A7A855_BIFAD	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EDN81920.1};	28.51	242	156	2	455	679	5	246	1e-22	108
rs:XP_010247445	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Nelumbo nucifera].	23.12	679	425	21	3	631	6	637	1e-22	113
rs:WP_012503239	DNA topoisomerase I [Chlorobaculum parvum].	24.59	675	399	22	3	629	15	627	1e-22	113
rs:XP_006410336	hypothetical protein EUTSA_v10016222mg [Eutrema salsugineum].	23.25	628	405	22	3	586	8	602	1e-22	113
rs:WP_035107542	DNA topoisomerase I, partial [Desulfovirgula thermocuniculi].	23.89	561	365	18	88	616	62	592	1e-22	113
rs:WP_004313592	DNA topoisomerase, partial [Bacteroides xylanisolvens].	27.46	335	225	10	349	676	37	360	1e-22	110
rs:WP_032821696	topoisomerase I, partial [Oenococcus oeni].	27.90	319	202	8	189	489	3	311	1e-22	109
rs:WP_013657322	DNA topoisomerase I [Cellulosilyticum lentocellum].	25.83	573	357	17	90	630	67	603	1e-22	113
rs:WP_036797036	hypothetical protein, partial [Leisingera caerulea].	22.76	602	384	16	44	574	31	622	1e-22	113
rs:WP_029175455	DNA topoisomerase I [Streptococcus suis].	23.74	577	372	19	83	629	72	610	1e-22	113
rs:WP_039257944	DNA topoisomerase I [Clostridium botulinum].	24.96	645	392	20	2	616	4	586	1e-22	113
rs:WP_011344688	DNA topoisomerase I [Carboxydothermus hydrogenoformans].	25.04	651	386	23	2	616	3	587	2e-22	113
rs:WP_044893781	DNA topoisomerase I [Bacillus alveayuensis].	25.23	555	356	21	105	630	82	606	2e-22	113
rs:WP_011916787	DNA topoisomerase I [Caldicellulosiruptor saccharolyticus].	24.87	587	360	18	83	629	59	604	2e-22	113
rs:WP_019369891	DNA topoisomerase I [Sphingomonas sp. ATCC 31555].	23.69	667	418	24	1	629	1	614	2e-22	113
rs:WP_028399000	DNA topoisomerase I [Bacillus panaciterrae].	24.74	582	378	22	105	655	82	634	2e-22	112
rs:WP_016483699	DNA topoisomerase I [Chthonomonas calidirosea].	25.12	601	371	22	88	642	62	629	2e-22	113
rs:WP_007953650	DNA topoisomerase I [Pelosinus fermentans].	24.42	651	389	23	3	616	5	589	2e-22	113
rs:WP_012846247	DNA topoisomerase I [Lactobacillus johnsonii].	25.35	568	350	22	103	635	86	614	2e-22	112
tr:A0A0B7MJT6_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.72	565	348	19	88	614	66	585	2e-22	112
rs:WP_023505674	DNA topoisomerase I [uncultured archaeon A07HR60].	23.12	744	453	32	2	661	6	714	2e-22	113
rs:WP_021635915	DNA topoisomerase I [Clostridium sp. KLE 1755].	24.11	560	357	14	90	616	67	591	2e-22	112
rs:WP_035505356	MULTISPECIES: DNA topoisomerase I [Halobacillus].	25.62	566	352	22	105	635	82	613	2e-22	112
rs:WP_012002246	DNA topoisomerase I [Pseudothermotoga lettingae].	25.20	619	374	23	2	594	4	559	2e-22	112
rs:WP_009490010	DNA topoisomerase I [Catellicoccus marimammalium].	23.52	574	367	19	90	630	70	604	2e-22	112
rs:WP_034984787	DNA topoisomerase III, partial [Bifidobacterium adolescentis].	28.51	242	156	2	455	679	18	259	2e-22	108
rs:WP_045503129	DNA topoisomerase I [Streptococcus gordonii].	24.22	578	367	21	83	629	70	607	2e-22	112
rs:WP_044664589	DNA topoisomerase I [Syntrophaceticus schinkii].	23.72	565	348	19	88	614	62	581	2e-22	112
rs:WP_044775437	DNA topoisomerase I [Streptococcus suis].	23.74	577	372	18	83	629	72	610	2e-22	112
tr:W0JKP4_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.90	738	438	33	1	661	1	684	2e-22	113
rs:WP_009731066	DNA topoisomerase 1 [Streptococcus sp. F0442].	24.83	576	366	22	83	629	69	606	2e-22	112
rs:WP_000179676	DNA topoisomerase I [Streptococcus oralis].	24.35	579	365	21	83	629	71	608	2e-22	112
rs:WP_000179650	DNA topoisomerase I [Streptococcus pneumoniae].	24.53	579	364	20	83	629	71	608	2e-22	112
rs:WP_042383308	DNA topoisomerase I [Geobacillus thermoglucosidasius].	24.75	509	326	18	157	635	132	613	2e-22	112
rs:WP_025027668	DNA topoisomerase I [Bacillus mannanilyticus].	25.61	570	352	19	103	635	79	613	2e-22	112
tr:D4LJ45_9FIRM	SubName: Full=Draft genome {ECO:0000313|EMBL:CBL19856.1};	33.05	233	134	7	3	219	5	231	2e-22	109
sp:TOP3B_ARATH	RecName: Full=DNA topoisomerase 3-beta; EC=5.99.1.2;	23.31	622	398	22	3	586	8	588	2e-22	113
rs:WP_024753357	DNA topoisomerase I [Treponema phagedenis].	24.77	650	391	22	3	618	17	602	2e-22	112
rs:WP_022305902	DNA topoisomerase [Roseburia sp. CAG:380].	25.57	348	218	7	271	578	37	383	2e-22	110
rs:WP_022144615	DNA topoisomerase [Ruminococcus sp. CAG:563].	25.43	586	351	19	76	616	52	596	2e-22	112
rs:WP_002695179	DNA topoisomerase I [Treponema phagedenis].	24.35	649	395	21	3	618	17	602	2e-22	112
rs:WP_003251768	MULTISPECIES: DNA topoisomerase I [Geobacillus].	24.75	509	326	18	157	635	132	613	2e-22	112
rs:WP_014549399	DNA topoisomerase I [Francisella tularensis].	25.80	597	374	20	74	629	51	619	2e-22	112
rs:WP_028843537	DNA topoisomerase I [Pseudothermotoga elfii].	25.20	619	374	23	2	594	4	559	2e-22	112
rs:WP_042749308	DNA topoisomerase I, partial [Lactobacillus gasseri].	25.40	567	351	21	103	635	81	609	2e-22	112
rs:WP_022447817	DNA topoisomerase [Firmicutes bacterium CAG:460].	23.64	698	425	25	3	668	4	625	2e-22	112
rs:WP_004834834	DNA topoisomerase I [Anaerococcus prevotii].	25.11	661	364	27	3	616	5	581	2e-22	112
rs:WP_003035615	DNA topoisomerase I [Francisella tularensis].	25.80	597	374	20	74	629	51	619	2e-22	112
tr:U1QGR1_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.12	744	453	32	2	661	75	783	2e-22	113
rs:WP_022669886	DNA topoisomerase I [Hippea alviniae].	22.96	662	413	18	1	629	1	598	2e-22	112
rs:WP_003648735	DNA topoisomerase I [Lactobacillus gasseri].	25.40	567	351	21	103	635	86	614	2e-22	112
rs:WP_022362848	DNA topoisomerase type IA central domain protein [Eggerthella sp. CAG:298].	23.61	699	400	29	1	616	1	648	2e-22	112
rs:WP_023599657	DNA topoisomerase I [Lactobacillus johnsonii].	24.66	580	365	19	90	635	73	614	2e-22	112
rs:WP_040486417	DNA topoisomerase I [Listeria grayi].	26.06	564	352	22	105	635	82	613	2e-22	112
tr:D1YJE5_LACGS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.40	567	351	21	103	635	39	567	2e-22	112
rs:WP_008002399	DNA topoisomerase I [Halorubrum aidingense].	22.24	742	453	29	2	661	6	705	2e-22	112
rs:WP_000179662	DNA topoisomerase I [Streptococcus sp. M334].	24.53	579	364	21	83	629	71	608	2e-22	112
rs:WP_044766305	DNA topoisomerase I [Streptococcus suis].	23.92	577	371	18	83	629	72	610	2e-22	112
rs:XP_010510115	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Camelina sativa].	23.99	621	395	24	3	586	8	588	2e-22	112
rs:WP_022348616	hypothetical protein [Collinsella sp. CAG:398].	23.35	561	358	18	87	616	133	652	2e-22	112
tr:K1T893_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC69387.1}; Flags: Fragment;	28.98	314	200	10	278	582	1	300	2e-22	108
rs:WP_009874718	topoisomerase I [Actinobacillus pleuropneumoniae].	23.78	593	376	17	74	631	88	639	2e-22	112
rs:WP_033683782	DNA topoisomerase I [Streptococcus mitis].	24.70	579	363	21	83	629	71	608	2e-22	112
rs:WP_000445598	DNA topoisomerase I [Streptococcus pneumoniae].	24.53	579	364	20	83	629	53	590	2e-22	112
rs:WP_045354052	topoisomerase I, partial [Lactobacillus plantarum].	34.53	223	128	7	3	212	4	221	2e-22	107
gpu:CP009524_1651	DNA topoisomerase I [Methanosarcina sp. Kolksee]	25.92	463	288	21	188	629	196	624	2e-22	112
rs:WP_025289380	DNA topoisomerase I [Bibersteinia trehalosi].	24.00	600	370	18	74	633	89	642	2e-22	112
rs:WP_032706893	DNA topoisomerase III, partial [Pseudomonas savastanoi].	30.41	217	136	5	1	210	1	209	2e-22	106
rs:WP_013159046	DNA topoisomerase I [Meiothermus silvanus].	23.33	720	395	28	3	660	7	631	2e-22	112
rs:WP_008938177	DNA topoisomerase I subunit omega [Marinobacter santoriniensis].	24.83	600	372	21	72	633	86	644	2e-22	112
rs:WP_022018119	DNA topoisomerase [Firmicutes bacterium CAG:129].	22.74	620	405	20	90	673	68	649	2e-22	112
rs:WP_039763835	DNA topoisomerase I [Caldicellulosiruptor sp. F32].	24.70	587	361	18	83	629	59	604	2e-22	112
rs:WP_040221470	DNA topoisomerase [Collinsella sp. MS5].	23.31	562	354	19	87	616	134	650	2e-22	112
rs:WP_027826532	DNA topoisomerase I [Lactobacillus saerimneri].	25.17	576	341	21	103	635	90	618	2e-22	112
rs:WP_037563553	DNA topoisomerase I [Streptococcus agalactiae].	24.27	581	364	21	83	629	79	617	2e-22	112
rs:WP_031471430	DNA topoisomerase I [[Clostridium] aminophilum].	25.18	556	355	19	90	616	67	590	3e-22	112
rs:XP_003102480	hypothetical protein CRE_04022 [Caenorhabditis remanei].	23.57	628	396	22	3	585	6	594	3e-22	112
tr:A0A061P3Q6_9BACL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.78	573	365	22	90	629	37	576	3e-22	112
rs:WP_028669789	DNA topoisomerase I [Saccharospirillum impatiens].	25.19	655	389	24	76	684	93	692	3e-22	112
rs:WP_046560792	DNA topoisomerase I [Kangiella geojedonensis].	25.08	610	374	22	65	633	79	646	3e-22	112
rs:WP_021962295	DNA topoisomerase [Mycoplasma sp. CAG:877].	24.66	657	398	23	3	629	5	594	3e-22	112
rs:WP_003651155	DNA topoisomerase I [Lactobacillus gasseri].	25.40	567	351	21	103	635	86	614	3e-22	112
rs:WP_002328882	hypothetical protein, partial [Enterococcus faecium].	37.99	179	100	5	49	218	1	177	3e-22	105
rs:WP_000320658	hypothetical protein, partial [Vibrio cholerae].	32.03	231	140	4	359	581	4	225	3e-22	107
tr:D7UYI7_LISGR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.06	564	352	22	105	635	93	624	3e-22	112
tr:J1JMX7_STREE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.53	579	364	20	83	629	24	561	3e-22	112
rs:WP_003647374	DNA topoisomerase I [Lactobacillus gasseri].	25.40	567	351	21	103	635	86	614	3e-22	112
rs:WP_009708791	DNA topoisomerase I [Desmospora sp. 8437].	24.74	570	359	22	103	636	80	615	3e-22	112
tr:E9FJZ9_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.53	579	364	21	83	629	77	614	3e-22	112
rs:WP_028052717	DNA topoisomerase I [Carboxydothermus ferrireducens].	24.88	651	387	23	2	616	3	587	3e-22	112
rs:WP_018692543	hypothetical protein [Algicola sagamiensis].	24.41	594	377	19	73	631	83	639	3e-22	112
rs:WP_045763428	DNA topoisomerase I [Streptococcus mitis].	24.87	579	362	22	83	629	71	608	3e-22	112
gpu:CP009520_1676	DNA topoisomerase I [Methanosarcina vacuolata Z-761]	25.60	461	292	20	188	629	196	624	3e-22	112
gp:AK221174_1	putative DNA topoisomerase III beta [Arabidopsis thaliana]	23.31	622	398	22	3	586	8	588	3e-22	112
tr:D4KTF6_9FIRM	SubName: Full=Draft genome {ECO:0000313|EMBL:CBL10158.1};	34.50	171	103	4	1	168	1	165	3e-22	105
rs:WP_022468862	DNA topoisomerase [Clostridium sp. CAG:451].	25.66	682	398	28	3	652	5	609	3e-22	112
rs:WP_000179652	DNA topoisomerase I [Streptococcus pneumoniae].	24.53	579	364	20	83	629	71	608	3e-22	112
rs:XP_008792952	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Phoenix dactylifera].	23.06	620	402	22	3	586	6	586	3e-22	112
rs:WP_011223762	DNA topoisomerase I [Haloarcula marismortui].	26.90	461	274	19	1	425	1	434	3e-22	113
rs:WP_039913780	DNA topoisomerase I [Cellvibrio mixtus].	24.42	651	399	24	76	684	93	692	3e-22	112
rs:WP_029751772	DNA topoisomerase I [Streptococcus suis].	24.49	584	359	20	83	629	72	610	3e-22	112
rs:WP_004897408	DNA topoisomerase I [Lactobacillus johnsonii].	24.66	580	365	19	90	635	73	614	3e-22	112
rs:WP_034755646	DNA topoisomerase I [Bacillus vietnamensis].	25.27	566	364	22	100	635	77	613	3e-22	112
rs:WP_029940950	DNA topoisomerase I, partial [Sphingomonas astaxanthinifaciens].	23.30	678	406	24	1	629	1	613	3e-22	112
rs:WP_031796378	DNA topoisomerase III, partial [Staphylococcus aureus].	33.92	227	129	8	3	214	4	224	3e-22	106
tr:V6Z0Z2_STRAG	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.27	581	364	21	83	629	76	614	3e-22	112
rs:WP_022378698	DNA topoisomerase type IA central domain protein [Cryptobacterium sp. CAG:338].	24.70	587	345	25	90	631	135	669	3e-22	112
rs:WP_010135732	DNA topoisomerase I [Flavobacteriaceae bacterium S85].	26.40	534	317	17	3	521	5	477	3e-22	112
rs:WP_012487618	topoisomerase I [Cellvibrio japonicus].	24.63	609	350	25	73	629	88	639	3e-22	112
rs:WP_018465097	hypothetical protein [Meiothermus timidus].	23.61	576	359	17	76	616	54	583	3e-22	112
rs:WP_013075487	DNA topoisomerase I [Kyrpidia tusciae].	24.36	583	377	19	88	636	62	614	3e-22	112
rs:WP_033613525	DNA topoisomerase, partial [Enterococcus faecium].	27.90	276	176	6	293	554	84	350	3e-22	108
rs:WP_003150200	DNA topoisomerase [Atopobium rimae].	24.65	572	332	26	90	616	137	654	3e-22	112
rs:WP_026574870	DNA topoisomerase I [Bacillus sp. UNC438CL73TsuS30].	24.87	563	361	21	105	635	82	614	3e-22	112
tr:A0A0D3B4H6_BRAOL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Bo3g026540.1};	22.84	613	412	20	3	586	8	588	3e-22	112
rs:WP_000445599	DNA topoisomerase I [Streptococcus pneumoniae].	24.53	579	364	20	83	629	53	590	3e-22	112
rs:WP_029176280	DNA topoisomerase I [Streptococcus suis].	23.92	577	371	18	83	629	72	610	3e-22	112
rs:WP_027963176	DNA topoisomerase I [Halalkalibacillus halophilus].	24.26	577	350	21	103	635	80	613	3e-22	112
rs:WP_012057245	DNA topoisomerase I [Thermosipho melanesiensis].	26.27	632	372	20	2	610	6	566	3e-22	112
rs:WP_010979235	DNA topoisomerase I [Sulfolobus tokodaii].	25.58	516	331	16	68	560	68	553	3e-22	112
rs:WP_010724793	hypothetical protein, partial [Enterococcus faecium].	27.90	276	176	6	293	554	89	355	3e-22	108
rs:WP_032088847	DNA topoisomerase I [Bacillus aquimaris].	25.44	570	348	23	105	635	82	613	3e-22	112
rs:WP_013725660	DNA topoisomerase I [Clostridium botulinum].	24.81	645	393	20	2	616	4	586	3e-22	112
rs:WP_044775889	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	3e-22	112
tr:S9RZV6_9RHOB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.31	290	189	7	298	572	2	290	3e-22	110
rs:WP_024377726	DNA topoisomerase I [Streptococcus suis].	24.31	576	370	18	83	629	72	610	3e-22	112
rs:WP_000179671	DNA topoisomerase I [Streptococcus oralis].	24.35	579	365	21	83	629	71	608	3e-22	112
rs:WP_039240575	DNA topoisomerase I [Clostridium botulinum].	24.81	645	393	20	2	616	4	586	3e-22	112
rs:WP_003024471	DNA topoisomerase I [Streptococcus anginosus].	24.44	577	367	22	83	629	70	607	3e-22	112
rs:WP_000179651	DNA topoisomerase I [Streptococcus pneumoniae].	24.53	579	364	20	83	629	71	608	3e-22	112
tr:A0A087GMR1_ARAAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.90	620	403	20	3	586	8	588	4e-22	112
rs:WP_004894564	DNA topoisomerase I [Lactobacillus johnsonii].	25.04	567	353	19	103	635	86	614	4e-22	112
rs:XP_010673315	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Beta vulgaris subsp. vulgaris].	22.96	675	431	24	3	631	6	637	4e-22	112
rs:WP_007934880	MULTISPECIES: DNA topoisomerase I [Pelosinus].	24.42	651	389	23	3	616	5	589	4e-22	112
rs:WP_005691979	topoisomerase I [Haemophilus influenzae].	25.58	473	298	13	187	633	196	640	4e-22	112
rs:WP_035342062	DNA topoisomerase III, partial [Dickeya sp. DW 0440].	33.80	213	112	9	1	196	1	201	4e-22	105
tr:H7QP91_STREE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.53	579	364	20	83	629	24	561	4e-22	111
rs:WP_006915168	DNA topoisomerase I [Salinisphaera shabanensis].	24.96	573	335	19	3	534	5	523	4e-22	112
rs:WP_044672450	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	4e-22	111
rs:XP_008337494	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Malus domestica].	22.67	666	443	22	3	631	7	637	4e-22	112
rs:WP_022033928	DNA topoisomerase [Clostridium sp. CAG:710].	25.27	657	396	24	3	629	5	596	4e-22	111
rs:WP_029171748	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	4e-22	111
rs:WP_032909719	DNA topoisomerase I [Streptococcus sanguinis].	25.22	575	365	21	83	629	70	607	4e-22	111
rs:WP_021055826	Topoisomerase IA [Haloquadratum walsbyi].	23.22	676	406	28	2	618	6	627	4e-22	112
rs:WP_004270304	DNA topoisomerase I [Lactobacillus curvatus].	23.95	572	372	17	90	629	68	608	4e-22	111
rs:WP_013867618	DNA topoisomerase I [Methanothermococcus okinawensis].	25.61	613	373	21	3	581	4	567	4e-22	112
tr:M4E275_BRARP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.79	610	413	18	3	586	8	585	4e-22	112
tr:F2C637_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.22	575	365	21	83	629	73	610	4e-22	111
rs:WP_044921529	hypothetical protein [Anaerostipes hadrus].	24.82	552	354	20	3	523	5	526	4e-22	111
rs:WP_005693995	DNA topoisomerase I [Haemophilus influenzae].	25.37	473	299	13	187	633	196	640	4e-22	112
rs:WP_044020637	DNA topoisomerase I [Streptococcus sp. VT 162].	24.35	579	365	21	83	629	71	608	4e-22	111
rs:WP_007187672	DNA topoisomerase I [Haloarcula californiae].	26.90	461	274	19	1	425	1	434	4e-22	112
rs:NP_001254382	Y48C3A.14, isoform c [Caenorhabditis elegans].	26.19	462	264	17	159	585	41	460	4e-22	111
tr:A0A0B4Y581_9PROT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AJD54325.1};	24.45	634	367	24	3	560	4	601	4e-22	112
tr:W4RI44_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE43578.1};	28.73	268	166	7	355	613	4	255	4e-22	107
tr:A0A0A1MVM7_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.55	683	432	28	3	631	7	646	4e-22	111
rs:WP_045591152	DNA topoisomerase I [Streptococcus mitis].	24.44	581	362	22	83	629	71	608	4e-22	111
rs:WP_028303438	DNA topoisomerase I [Oceanospirillum maris].	25.13	593	367	18	76	633	94	644	4e-22	112
rs:WP_024376241	DNA topoisomerase I [Streptococcus suis].	23.74	577	372	18	83	629	72	610	4e-22	111
tr:W5FY75_WHEAT	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Traes_5DL_BE2E29504.1};	22.91	659	420	27	3	614	6	623	4e-22	112
rs:WP_031811097	DNA topoisomerase III, partial [Staphylococcus aureus].	37.57	181	100	5	3	178	4	176	4e-22	105
rs:WP_014567529	DNA topoisomerase I [Lactobacillus johnsonii].	25.04	567	353	19	103	635	86	614	4e-22	111
rs:WP_041784112	DNA topoisomerase I, partial [Streptococcus anginosus].	24.57	578	365	22	83	629	70	607	4e-22	111
rs:WP_003030274	DNA topoisomerase I [Streptococcus anginosus].	24.57	578	365	22	83	629	70	607	4e-22	111
tr:T1ZVG1_STRAP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.57	578	365	22	83	629	70	607	4e-22	111
rs:WP_033396689	hypothetical protein, partial [Thermodesulfobacterium thermophilum].	26.97	571	348	20	2	557	4	520	4e-22	110
rs:WP_021858644	DNA topoisomerase [Firmicutes bacterium CAG:83].	21.73	626	417	18	83	673	64	651	4e-22	111
rs:WP_014296545	DNA topoisomerase I [Marinitoga piezophila].	25.47	644	384	23	2	616	7	583	4e-22	111
tr:E6QVF7_9ZZZZ	SubName: Full=DNA topoisomerase 1 (DNA topoisomerase I) (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) {ECO:0000313|EMBL:CBI11230.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI11230.1};	23.93	610	359	22	76	630	52	611	4e-22	112
rs:WP_000179645	DNA topoisomerase I [Streptococcus pneumoniae].	24.05	578	368	18	83	629	71	608	4e-22	111
rs:WP_037614931	DNA topoisomerase I [Streptococcus sinensis].	24.57	578	365	21	83	629	70	607	4e-22	111
tr:F9PVG5_9STRE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	25.15	505	312	20	154	629	1	468	4e-22	110
rs:WP_018543479	MULTISPECIES: DNA topoisomerase I [Streptococcus anginosus group].	24.57	578	365	22	83	629	70	607	5e-22	111
rs:WP_019128852	DNA topoisomerase [Enorma massiliensis].	23.17	561	359	18	87	616	133	652	5e-22	112
rs:WP_015593131	DNA topoisomerase I [Bacillus sp. 1NLA3E].	24.42	561	367	21	105	636	82	614	5e-22	111
rs:WP_031826166	DNA topoisomerase III, partial [Staphylococcus aureus].	37.57	181	100	5	3	178	4	176	5e-22	105
tr:K1YG08_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.52	678	384	28	1	630	1	605	5e-22	111
rs:WP_000179663	DNA topoisomerase I [Streptococcus mitis].	24.53	579	364	21	83	629	71	608	5e-22	111
rs:WP_000179646	DNA topoisomerase I [Streptococcus pneumoniae].	24.01	579	369	18	83	630	71	609	5e-22	111
rs:WP_000179668	DNA topoisomerase I [Streptococcus sp. oral taxon 058].	24.35	579	365	21	83	629	71	608	5e-22	111
rs:WP_022450308	DNA topoisomerase [Roseburia sp. CAG:303].	26.39	360	210	13	287	594	2	358	5e-22	108
rs:WP_024460340	DNA topoisomerase I [Marinimicrobium sp. LS-A18].	24.26	606	372	21	57	629	88	639	5e-22	111
sp:TOP1_THEMA	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.58	645	366	23	2	616	7	567	5e-22	111
rs:WP_031921849	DNA topoisomerase III, partial [Staphylococcus aureus].	34.40	218	122	8	3	205	4	215	5e-22	106
rs:WP_025489727	DNA topoisomerase I [Clostridiales bacterium VE202-27].	24.11	560	357	14	90	616	67	591	5e-22	111
rs:WP_031844272	DNA topoisomerase III, partial [Staphylococcus aureus].	37.57	181	100	5	3	178	4	176	5e-22	105
rs:WP_031887577	DNA topoisomerase III, partial [Staphylococcus aureus].	37.57	181	100	5	3	178	4	176	5e-22	105
rs:XP_007225297	hypothetical protein PRUPE_ppa001274mg [Prunus persica].	22.99	670	436	22	3	631	7	637	5e-22	111
rs:WP_022798377	DNA topoisomerase I [Thermus islandicus].	24.20	653	383	22	3	616	15	594	5e-22	111
rs:WP_000179657	DNA topoisomerase I [Streptococcus mitis].	24.53	579	364	21	83	629	71	608	5e-22	111
rs:WP_000179632	DNA topoisomerase I [Streptococcus pneumoniae].	24.05	578	368	18	83	629	71	608	5e-22	111
rs:WP_004101613	DNA topoisomerase I [Thermosipho africanus].	24.60	626	388	16	3	610	1	560	5e-22	111
rs:WP_028117526	DNA topoisomerase I [Ferrimonas senticii].	24.28	593	373	20	77	633	93	645	5e-22	111
rs:WP_031764727	DNA topoisomerase I [Staphylococcus aureus].	24.82	568	368	17	90	629	67	603	5e-22	111
rs:WP_025236016	DNA topoisomerase I [Mannheimia varigena].	24.19	587	381	17	74	631	87	638	5e-22	111
rs:WP_000179656	DNA topoisomerase I [Streptococcus pseudopneumoniae].	24.53	579	364	21	83	629	71	608	5e-22	111
rs:WP_028263348	DNA topoisomerase [Atopobium fossor].	23.64	571	366	19	78	620	126	654	5e-22	111
rs:WP_044776982	DNA topoisomerase I [Streptococcus suis].	24.13	576	371	18	83	629	72	610	5e-22	111
rs:WP_018378171	DNA topoisomerase I [Streptococcus ovis].	23.74	577	372	18	83	629	72	610	5e-22	111
rs:WP_018257964	DNA topoisomerase I [Halomicrobium katesii].	24.01	658	407	29	1	616	1	607	5e-22	111
rs:WP_027323376	DNA topoisomerase I [Bacillus sp. URHB0009].	23.69	553	367	17	105	630	82	606	5e-22	111
tr:A0A090S0S8_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL20084.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL20084.1};	33.97	209	121	6	2	199	3	205	6e-22	106
rs:WP_031793687	DNA topoisomerase I [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	6e-22	111
rs:WP_044759764	DNA topoisomerase I [Streptococcus suis].	24.13	576	371	18	83	629	72	610	6e-22	111
rs:WP_000179672	DNA topoisomerase I [Streptococcus mitis].	24.35	579	365	21	83	629	71	608	6e-22	111
rs:WP_017548529	DNA topoisomerase I [Salinicoccus carnicancri].	23.92	556	362	19	103	629	80	603	6e-22	111
rs:WP_013758112	DNA topoisomerase I [Treponema brennaborense].	25.71	494	313	15	163	630	155	620	6e-22	111
rs:WP_014947339	DNA topoisomerase I [Streptococcus pneumoniae].	24.35	579	365	20	83	629	71	608	6e-22	111
rs:WP_011322338	DNA topoisomerase I [Natronomonas pharaonis].	24.32	658	405	30	1	616	1	607	6e-22	111
rs:WP_038805367	DNA topoisomerase I [Streptococcus dentisani].	24.35	579	365	21	83	629	71	608	6e-22	111
rs:WP_029943206	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	6e-22	111
sp:TOP1_HAEIN	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.37	473	299	13	187	633	196	640	6e-22	111
tr:J9FSD0_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central domain protein {ECO:0000313|EMBL:EJW97866.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EJW97866.1}; Flags: Fragment;	28.74	261	170	6	327	583	10	258	6e-22	107
rs:WP_045617272	DNA topoisomerase I [Streptococcus mitis].	24.18	579	366	21	83	629	71	608	6e-22	111
rs:WP_027431366	DNA topoisomerase I [Lachnospira multipara].	22.99	648	402	20	3	616	5	589	6e-22	111
rs:WP_010976540	DNA topoisomerase I [Streptococcus pneumoniae].	24.01	579	369	18	83	630	77	615	6e-22	111
rs:WP_033858482	DNA topoisomerase III, partial [Staphylococcus aureus].	34.40	218	122	8	3	205	4	215	6e-22	106
gpu:CP009506_1343	DNA topoisomerase I [Methanosarcina siciliae T4/M]	26.15	478	303	21	188	646	196	642	6e-22	111
rs:WP_014865375	DNA topoisomerase I [Natrinema sp. J7-2].	21.96	715	456	26	1	661	1	667	6e-22	111
rs:WP_044634342	DNA topoisomerase I [Treponema phagedenis].	24.62	650	392	22	3	618	17	602	6e-22	111
rs:WP_031580966	DNA topoisomerase I [Lachnospiraceae bacterium AC2028].	23.92	627	386	25	90	675	67	643	6e-22	111
rs:WP_012580135	DNA topoisomerase I [Thermosipho africanus].	24.72	627	388	16	2	610	6	566	6e-22	111
rs:XP_008222782	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Prunus mume].	23.88	670	430	24	3	631	7	637	6e-22	111
rs:WP_000179628	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.31	580	364	22	83	629	71	608	6e-22	111
rs:WP_022474281	DNA topoisomerase [Ruminococcus sp. CAG:353].	24.15	588	366	21	82	629	58	605	6e-22	111
rs:WP_046953148	DNA topoisomerase I [Haemophilus haemolyticus].	25.16	473	300	13	187	633	196	640	6e-22	111
rs:WP_044693788	DNA topoisomerase I, partial [Streptococcus suis].	23.83	579	369	19	83	629	72	610	6e-22	110
rs:WP_016477303	DNA topoisomerase I [Atopobium sp. oral taxon 199].	23.93	702	400	31	1	616	1	654	6e-22	111
rs:WP_044758837	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	6e-22	111
rs:XP_009132830	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Brassica rapa].	22.42	611	417	18	3	586	8	588	6e-22	111
rs:WP_019517463	DNA topoisomerase I [Sphingomonas sp. Mn802worker].	23.27	666	422	23	1	629	1	614	6e-22	111
rs:WP_042753922	DNA topoisomerase I [Streptococcus anginosus].	24.44	577	367	22	83	629	70	607	6e-22	111
gpu:CP009507_1289	DNA topoisomerase I [Methanosarcina siciliae HI350]	26.15	478	303	21	188	646	196	642	6e-22	111
rs:WP_046939159	DNA topoisomerase I [Haemophilus haemolyticus].	25.16	473	300	13	187	633	196	640	6e-22	111
tr:A0A090VXE1_9FLAO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL68623.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL68623.1};	27.91	326	212	11	371	678	2	322	7e-22	108
rs:WP_013175125	DNA topoisomerase I [Syntrophothermus lipocalidus].	24.08	569	374	16	90	630	64	602	7e-22	110
rs:WP_022214408	DNA topoisomerase [Blautia sp. CAG:237].	23.67	566	348	21	90	616	67	587	7e-22	110
rs:WP_005709862	topoisomerase I [Haemophilus paraphrohaemolyticus].	24.07	594	373	18	74	631	87	638	7e-22	111
rs:WP_022318561	DNA topoisomerase [Dorea sp. CAG:317].	22.59	642	412	20	3	616	5	589	7e-22	110
rs:WP_000179648	DNA topoisomerase I [Streptococcus pneumoniae].	24.05	578	368	18	83	629	71	608	7e-22	110
rs:WP_036721378	DNA topoisomerase I [Paracoccus sphaerophysae].	23.50	715	425	32	1	659	1	649	7e-22	111
rs:WP_000179620	DNA topoisomerase I [Streptococcus pneumoniae].	24.05	578	368	18	83	629	71	608	7e-22	110
rs:WP_015432594	DNA topoisomerase 1 [Bibersteinia trehalosi].	24.58	476	298	12	187	633	199	642	7e-22	111
rs:WP_039688410	DNA topoisomerase [Coriobacteriaceae bacterium 68-1-3].	24.01	758	426	33	1	664	1	702	7e-22	111
rs:WP_024385241	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	7e-22	110
rs:WP_000179670	DNA topoisomerase I [Streptococcus oralis].	24.35	579	365	21	83	629	71	608	7e-22	110
tr:W1TZD8_STRAP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.44	577	367	22	83	629	73	610	7e-22	110
rs:WP_000474619	hypothetical protein, partial [Streptococcus agalactiae].	26.90	394	249	11	191	574	1	365	7e-22	108
rs:WP_021687743	DNA topoisomerase I [Treponema lecithinolyticum].	25.38	587	364	21	90	643	79	624	7e-22	110
rs:WP_010184446	DNA topoisomerase I [Sphingomonas sp. PAMC 26605].	23.32	669	418	21	1	629	1	614	7e-22	111
rs:WP_021974605	DNA topoisomerase [Firmicutes bacterium CAG:884].	24.17	662	391	24	3	629	5	590	7e-22	110
rs:WP_000179667	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.35	579	365	21	83	629	71	608	7e-22	110
rs:XP_009619599	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Nicotiana tomentosiformis].	22.74	664	445	22	3	631	6	636	7e-22	111
rs:WP_003041712	DNA topoisomerase I [Francisella tularensis].	25.46	597	376	20	74	629	51	619	7e-22	111
rs:WP_008543520	toprim domain protein, partial [Sutterella parvirubra].	32.10	243	140	8	3	232	5	235	7e-22	107
rs:WP_003033127	DNA topoisomerase I [Francisella tularensis].	25.46	597	376	20	74	629	51	619	7e-22	111
rs:WP_026689912	DNA topoisomerase I [Bacillus aurantiacus].	24.46	560	368	20	105	636	82	614	7e-22	110
tr:A0A0B2VSG7_TOXCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.40	594	376	23	3	552	62	620	7e-22	111
rs:XP_010247446	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Nelumbo nucifera].	23.05	681	427	21	1	631	1	634	7e-22	111
rs:WP_000179647	DNA topoisomerase I, partial [Streptococcus pneumoniae].	24.05	578	368	18	83	629	71	608	7e-22	110
rs:WP_029669905	DNA topoisomerase I [Streptococcus pneumoniae].	24.05	578	368	18	83	629	53	590	7e-22	110
rs:WP_004957538	DNA topoisomerase I [Haloarcula sinaiiensis].	26.84	462	273	20	1	425	1	434	7e-22	111
rs:WP_001844626	DNA topoisomerase I [Streptococcus pneumoniae].	24.35	579	365	20	83	629	71	608	7e-22	110
rs:WP_003014690	DNA topoisomerase I [Francisella tularensis].	25.46	597	376	20	74	629	51	619	7e-22	110
rs:WP_041285335	DNA topoisomerase I, partial [Desulfotomaculum gibsoniae].	23.84	562	362	17	88	616	65	593	7e-22	110
rs:WP_033681703	DNA topoisomerase I [Streptococcus mitis].	24.53	579	364	21	83	629	53	590	8e-22	110
rs:WP_031879277	DNA topoisomerase III, partial [Staphylococcus aureus].	34.40	218	122	8	3	205	4	215	8e-22	105
rs:WP_024385723	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	8e-22	110
tr:A0A0A1NEC9_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.55	683	432	28	3	631	7	646	8e-22	111
rs:WP_008193802	MULTISPECIES: DNA topoisomerase I [Thermotoga].	25.58	645	366	23	2	616	7	567	8e-22	110
rs:WP_024380821	DNA topoisomerase I [Streptococcus suis].	23.74	577	372	18	83	629	72	610	8e-22	110
rs:WP_002358260	DNA topoisomerase, partial [Enterococcus faecium].	26.25	301	202	7	355	639	2	298	8e-22	107
gp:CP006730_602	DNA topoisomerase I [Dehalococcoides mccartyi GY50]	25.22	674	386	26	2	624	4	610	8e-22	110
gpu:CP011770_2062	DNA topoisomerase I [Croceicoccus naphthovorans]	22.88	673	419	21	1	634	1	612	8e-22	111
tr:E4LJS5_9FIRM	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:EFR40693.1};	28.12	345	213	11	308	629	2	334	8e-22	108
rs:WP_014638935	DNA topoisomerase I [Streptococcus suis].	23.92	577	371	18	83	629	72	610	8e-22	110
tr:V2BSP1_SALDE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESH31240.1};	29.31	232	157	4	381	608	1	229	8e-22	106
rs:WP_003042684	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.39	578	366	22	83	629	70	607	8e-22	110
rs:WP_010503653	DNA topoisomerase I subunit omega [Gluconobacter frateurii].	23.24	641	390	23	55	629	28	632	8e-22	111
rs:WP_044762879	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	8e-22	110
rs:WP_009106276	DNA topoisomerase I [Desulfovibrio sp. U5L].	24.79	609	351	23	79	640	53	601	8e-22	110
rs:WP_024408846	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	8e-22	110
rs:WP_044762088	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	8e-22	110
rs:WP_042767797	DNA topoisomerase I [Streptococcus sp. DBCMS].	24.14	580	365	22	83	629	71	608	8e-22	110
rs:WP_000179627	DNA topoisomerase I [Streptococcus mitis].	24.31	580	364	22	83	629	71	608	8e-22	110
rs:WP_018111526	DNA topoisomerase I [Thermus igniterrae].	24.53	579	351	20	77	616	50	581	8e-22	110
rs:WP_004195696	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	8e-22	110
rs:WP_024394484	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	8e-22	110
rs:WP_003017863	DNA topoisomerase I [Francisella tularensis].	25.46	597	376	20	74	629	51	619	8e-22	110
rs:WP_044768045	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	8e-22	110
rs:WP_000179654	DNA topoisomerase I [Streptococcus pseudopneumoniae].	24.53	579	364	21	83	629	71	608	9e-22	110
rs:XP_011000014	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Populus euphratica].	22.59	673	436	23	3	631	7	638	9e-22	110
rs:WP_033606327	DNA topoisomerase I [Streptococcus sp. CM6].	24.31	580	364	22	83	629	71	608	9e-22	110
rs:WP_036171681	DNA topoisomerase I [Lysinibacillus massiliensis].	24.37	554	361	18	105	629	82	606	9e-22	110
rs:WP_040197506	DNA topoisomerase I [Candidatus Soleaferrea massiliensis].	24.08	710	433	26	3	674	4	645	9e-22	110
rs:WP_022179515	DNA topoisomerase [Firmicutes bacterium CAG:582].	25.38	658	397	23	1	629	1	593	9e-22	110
rs:WP_007474867	DNA topoisomerase I [Caminibacter mediatlanticus].	25.15	660	395	24	2	629	4	596	9e-22	110
gpu:CP009530_812	DNA topoisomerase I [Methanosarcina barkeri 227]	24.78	460	297	17	188	629	196	624	9e-22	110
rs:WP_003026515	DNA topoisomerase I [Francisella tularensis].	25.46	597	376	20	74	629	51	619	9e-22	110
rs:WP_034344989	hypothetical protein [Helicobacter trogontum].	26.53	554	343	20	46	575	30	543	9e-22	110
rs:WP_006064421	DNA topoisomerase I [Natronorubrum bangense].	22.73	695	431	30	1	642	1	642	9e-22	110
rs:WP_024390017	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	9e-22	110
rs:WP_000179673	DNA topoisomerase I [Streptococcus mitis].	24.35	579	365	21	83	629	71	608	9e-22	110
rs:WP_044754361	DNA topoisomerase I [Streptococcus suis].	23.74	577	372	19	83	629	72	610	9e-22	110
rs:WP_000179624	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.14	580	365	22	83	629	71	608	9e-22	110
rs:WP_003038456	DNA topoisomerase I [Francisella tularensis].	25.46	597	376	20	74	629	51	619	9e-22	110
rs:WP_015790454	DNA topoisomerase I [Halorhabdus utahensis].	22.50	649	428	31	1	616	1	607	9e-22	110
rs:XP_006358793	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X1 [Solanum tuberosum].	22.75	668	440	23	3	631	6	636	9e-22	110
rs:WP_036868867	DNA topoisomerase I, partial [Prevotella bivia].	34.41	186	104	4	4	178	5	183	9e-22	104
rs:WP_046400761	DNA topoisomerase I [Francisella tularensis].	25.46	597	376	20	74	629	45	613	9e-22	110
rs:WP_024407141	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	9e-22	110
rs:WP_013028145	DNA topoisomerase I [Sideroxydans lithotrophicus].	25.52	674	392	25	3	630	5	614	9e-22	110
tr:A0A081PQQ6_STRMT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.53	579	364	21	83	629	24	561	1e-21	110
rs:WP_015732803	DNA topoisomerase I [Methanocaldococcus vulcanius].	31.16	337	199	12	3	322	4	324	1e-21	110
rs:WP_033688907	DNA topoisomerase I [Streptococcus mitis].	24.53	579	364	21	83	629	53	590	1e-21	110
rs:XP_002140607	DNA topoisomerase family protein [Cryptosporidium muris RN66].	24.13	659	416	26	3	614	32	653	1e-21	110
tr:J6PTL9_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EJX56890.1}; Flags: Fragment;	34.09	176	110	3	41	210	27	202	1e-21	104
rs:WP_042057047	DNA topoisomerase I, partial [Acidomonas methanolica].	22.94	632	405	20	55	630	28	633	1e-21	110
tr:A0A0B3AMM6_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.21	685	423	25	1	639	1	628	1e-21	110
rs:WP_003034456	DNA topoisomerase I [Streptococcus anginosus].	24.39	578	366	22	83	629	70	607	1e-21	110
rs:WP_009795914	MULTISPECIES: DNA topoisomerase I [Bacillus].	25.27	554	357	19	105	630	82	606	1e-21	110
tr:A0A081QGC6_STRMT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.53	579	364	21	83	629	24	561	1e-21	110
rs:WP_036217009	DNA topoisomerase I [Marinospirillum minutulum].	24.14	613	357	22	73	633	78	634	1e-21	110
tr:K8ECN4_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.48	569	343	23	88	616	62	589	1e-21	110
rs:WP_041330812	DNA topoisomerase I [Dehalococcoides mccartyi].	25.22	674	386	26	2	624	4	610	1e-21	110
tr:E6J331_STRAP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.39	578	366	22	83	629	73	610	1e-21	110
rs:WP_014255154	DNA topoisomerase I [[Clostridium] clariflavum].	25.66	565	341	19	90	616	67	590	1e-21	110
rs:WP_023944543	DNA topoisomerase 1 [Gluconobacter frateurii].	23.20	638	394	23	55	629	28	632	1e-21	110
rs:WP_019214705	hypothetical protein [Clostridiales bacterium 9401234].	25.82	670	389	27	1	629	1	603	1e-21	110
tr:A0A023D3N6_ACIMT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.94	632	405	20	55	630	28	633	1e-21	110
rs:WP_044791351	DNA topoisomerase I [Streptococcus pneumoniae].	24.35	579	365	20	83	629	71	608	1e-21	110
rs:WP_000179666	DNA topoisomerase I [Streptococcus oralis].	24.18	579	366	21	83	629	71	608	1e-21	110
rs:WP_002936490	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	1e-21	110
rs:WP_024118930	DNA topoisomerase I [Thermus thermophilus].	24.55	668	365	25	3	616	18	600	1e-21	110
rs:WP_023940227	DNA topoisomerase I [Streptococcus pseudopneumoniae].	24.96	581	359	21	83	629	71	608	1e-21	110
rs:WP_010193401	DNA topoisomerase I [Bacillus sp. m3-13].	24.38	566	362	21	105	636	82	615	1e-21	110
rs:WP_024410540	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	1e-21	110
rs:WP_024381859	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	1e-21	110
rs:WP_000179649	DNA topoisomerase I [Streptococcus pneumoniae].	24.05	578	368	18	83	629	71	608	1e-21	110
rs:WP_044993277	DNA topoisomerase I [Lachnospiraceae bacterium JC7].	23.78	635	407	21	3	616	5	583	1e-21	110
gpu:CP009517_952	DNA topoisomerase I [Methanosarcina barkeri 3]	25.49	463	290	20	188	629	196	624	1e-21	110
rs:WP_011161948	DNA topoisomerase I [Lactobacillus johnsonii].	24.87	567	354	19	103	635	86	614	1e-21	110
rs:WP_000179643	DNA topoisomerase I [Streptococcus pneumoniae].	24.35	579	365	20	83	629	71	608	1e-21	110
rs:WP_000179631	DNA topoisomerase I [Streptococcus pneumoniae].	24.35	579	365	20	83	629	71	608	1e-21	110
rs:WP_024409355	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	1e-21	110
tr:R4KF98_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952}; Flags: Precursor;	23.84	562	362	17	88	616	62	590	1e-21	110
rs:XP_002177365	DNA topoisomerase, partial [Phaeodactylum tricornutum CCAP 1055/1].	23.95	664	393	25	3	601	4	620	1e-21	110
rs:WP_044670821	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	1e-21	110
rs:WP_000179618	DNA topoisomerase I [Streptococcus pneumoniae].	24.35	579	365	20	83	629	71	608	1e-21	110
rs:WP_008474129	DNA topoisomerase I [Lactobacillus gigeriorum].	25.44	574	343	23	103	635	89	618	1e-21	110
rs:WP_024419473	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	1e-21	110
rs:WP_000179625	DNA topoisomerase I [Streptococcus oralis].	24.14	580	365	22	83	629	71	608	1e-21	110
rs:WP_017551515	DNA topoisomerase I [Bacillus coagulans].	24.47	568	356	22	105	635	82	613	1e-21	110
rs:WP_005641907	topoisomerase I [Haemophilus haemolyticus].	25.21	472	301	13	187	633	196	640	1e-21	110
rs:WP_010406126	DNA topoisomerase I [Sphingomonas echinoides].	23.45	678	406	26	1	629	1	614	1e-21	110
rs:WP_000445596	DNA topoisomerase I [Streptococcus pneumoniae].	24.35	579	365	20	83	629	53	590	1e-21	110
rs:WP_033687089	DNA topoisomerase I [Streptococcus mitis].	24.35	579	365	21	83	629	53	590	1e-21	110
rs:WP_035188460	DNA topoisomerase I [Bacillus coagulans].	24.47	568	356	22	105	635	82	613	1e-21	110
rs:WP_024397127	DNA topoisomerase I [Streptococcus suis].	23.74	577	372	19	83	629	72	610	1e-21	110
tr:H3G0S1_PRIPA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.26	632	380	25	3	586	6	580	1e-21	110
rs:WP_046983426	DNA topoisomerase I [Thermomonas brevis].	25.26	578	334	20	3	538	5	526	1e-21	110
rs:WP_012035171	DNA topoisomerase I [Methanocella arvoryzae].	23.39	667	425	26	1	630	1	618	1e-21	110
rs:WP_044688674	DNA topoisomerase I [Streptococcus suis].	23.74	577	372	18	83	629	72	610	1e-21	110
rs:WP_022648322	MULTISPECIES: DNA topoisomerase 1 [Enterobacter].	24.06	586	384	18	76	633	82	634	1e-21	110
rs:WP_042803046	DNA topoisomerase I [Mannheimia haemolytica].	24.58	594	370	22	74	631	87	638	1e-21	110
rs:WP_044769733	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	1e-21	110
rs:WP_007516861	DNA topoisomerase I [Streptococcus tigurinus].	24.18	579	366	21	83	629	71	608	1e-21	110
rs:XP_002966408	hypothetical protein SELMODRAFT_168492 [Selaginella moellendorffii].	22.39	603	407	19	37	612	32	600	1e-21	110
rs:WP_000179644	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	71	608	1e-21	110
rs:WP_007522106	DNA topoisomerase I [Streptococcus tigurinus].	24.18	579	366	22	83	629	71	608	1e-21	110
rs:WP_008896716	DNA topoisomerase I [Haloterrigena salina].	21.21	693	442	22	1	642	1	640	1e-21	110
rs:WP_012301722	DNA topoisomerase I [Candidatus Desulforudis audaxviator].	24.29	704	414	30	3	656	5	639	1e-21	110
rs:WP_046619715	DNA topoisomerase I [Enterobacter cloacae].	24.06	586	384	18	76	633	82	634	1e-21	110
rs:WP_045597118	DNA topoisomerase I [Streptococcus mitis].	24.35	579	365	21	83	629	71	608	1e-21	110
rs:WP_039270612	DNA topoisomerase I [Enterobacter cloacae].	24.79	589	376	21	76	633	82	634	1e-21	110
rs:WP_012481370	DNA topoisomerase I [Stenotrophomonas maltophilia].	24.91	578	336	20	3	538	5	526	1e-21	110
rs:WP_023300259	DNA topoisomerase 1 [Enterobacter cloacae].	24.06	586	384	18	76	633	82	634	1e-21	110
rs:WP_020901448	DNA topoisomerase I [Streptococcus mitis].	24.14	580	365	22	83	629	71	608	1e-21	110
rs:WP_043034573	DNA topoisomerase I [Stenotrophomonas maltophilia].	24.91	578	336	20	3	538	5	526	1e-21	110
rs:WP_036171533	DNA topoisomerase I [Lysobacter dokdonensis].	25.46	491	303	16	85	538	62	526	1e-21	110
rs:WP_032622442	DNA topoisomerase I [Lelliottia amnigena].	24.06	586	384	18	76	633	82	634	1e-21	110
rs:WP_041964483	DNA topoisomerase I [Bacillus selenatarsenatis].	24.32	555	359	19	105	629	82	605	1e-21	110
rs:WP_025056227	DNA topoisomerase I [Sulfitobacter sp. NB-77].	23.27	679	413	24	1	629	1	621	1e-21	110
rs:WP_000179619	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	71	608	1e-21	110
tr:R0MTD2_STRMT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.35	579	365	21	83	629	19	556	1e-21	109
rs:WP_046789963	DNA topoisomerase I [Salinicoccus halodurans].	24.29	560	355	23	103	629	80	603	1e-21	110
rs:WP_029998768	DNA topoisomerase I [Streptococcus suis].	23.66	579	370	19	83	629	72	610	1e-21	110
rs:WP_046942317	DNA topoisomerase I [Haemophilus haemolyticus].	25.16	473	300	13	187	633	196	640	1e-21	110
rs:WP_007257738	DNA topoisomerase I [Natronolimnobius innermongolicus].	21.87	727	443	26	1	661	1	668	1e-21	110
rs:WP_047353322	DNA topoisomerase I [Enterobacter sp. GN02315].	24.06	586	384	18	76	633	82	634	1e-21	110
rs:WP_000179675	DNA topoisomerase I [Streptococcus oralis].	24.31	576	369	19	83	629	71	608	1e-21	110
rs:WP_004319202	DNA topoisomerase I [Campylobacter rectus].	25.10	522	326	17	100	587	72	562	1e-21	109
rs:WP_024387763	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	1e-21	110
rs:WP_045341511	DNA topoisomerase I [Enterobacter cloacae].	24.79	589	376	21	76	633	82	634	1e-21	110
rs:WP_000179660	DNA topoisomerase I [Streptococcus mitis].	24.53	579	364	21	83	629	71	608	1e-21	110
rs:WP_013730365	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	1e-21	110
rs:WP_015646822	DNA topoisomerase I [Streptococcus suis].	23.66	579	370	19	83	629	72	610	1e-21	110
rs:WP_014636962	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	1e-21	110
rs:WP_017727299	DNA topoisomerase I [Bacillus sp. L1(2012)].	24.37	554	366	19	103	630	80	606	1e-21	110
rs:WP_005637796	topoisomerase I [Haemophilus haemolyticus].	25.16	473	300	13	187	633	196	640	1e-21	110
rs:WP_027883605	DNA topoisomerase I [Meiothermus rufus].	25.34	580	341	22	76	616	54	580	1e-21	110
rs:WP_022525855	topoisomerase IA [Streptococcus anginosus].	24.39	578	366	22	83	629	70	607	1e-21	110
rs:WP_032836200	DNA topoisomerase I [Fusobacterium sp. OBRC1].	24.75	695	432	22	2	671	12	640	1e-21	110
rs:WP_019820987	topoisomerase I [Vibrio splendidus].	23.88	603	369	19	74	633	84	639	1e-21	110
rs:WP_010945247	topoisomerase I [Haemophilus ducreyi].	24.53	587	379	18	74	631	86	637	1e-21	110
rs:WP_027074603	DNA topoisomerase I [Mannheimia granulomatis].	24.45	593	372	20	74	631	87	638	1e-21	110
rs:WP_044771230	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	1e-21	110
rs:WP_044686750	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	1e-21	110
rs:WP_040008887	DNA topoisomerase I [Francisella sp. FSC1006].	25.46	597	376	21	74	629	51	619	1e-21	110
rs:WP_000445597	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	53	590	1e-21	109
rs:WP_041171366	DNA topoisomerase I [Streptococcus pneumoniae].	24.35	579	365	20	83	629	71	608	1e-21	110
rs:WP_013527698	topoisomerase I [Haemophilus influenzae].	25.47	475	296	14	187	633	196	640	1e-21	110
rs:WP_000179658	DNA topoisomerase I [Streptococcus mitis].	24.35	579	365	21	83	629	71	608	1e-21	110
rs:WP_037332935	DNA topoisomerase I [Salinisphaera hydrothermalis].	23.83	575	340	20	3	534	5	524	1e-21	110
rs:WP_015778211	DNA topoisomerase I [Anaerococcus prevotii].	26.04	676	371	31	3	630	5	599	1e-21	109
rs:WP_017977323	DNA topoisomerase I [Sphingomonas melonis].	23.05	668	421	23	1	629	1	614	1e-21	110
rs:WP_000179659	DNA topoisomerase I [Streptococcus mitis].	24.35	579	365	21	83	629	71	608	1e-21	110
rs:WP_021985356	DNA topoisomerase [Clostridium sp. CAG:127].	26.95	564	325	24	90	616	67	580	1e-21	109
rs:WP_017384217	MULTISPECIES: topoisomerase I [Enterobacter cloacae complex].	24.79	589	376	21	76	633	82	634	1e-21	110
rs:WP_027886918	MULTISPECIES: DNA topoisomerase I [Meiothermus].	24.13	688	369	28	3	616	6	614	1e-21	110
rs:XP_010469641	PREDICTED: DNA topoisomerase 3-beta-like [Camelina sativa].	23.14	618	404	22	3	586	8	588	1e-21	110
rs:WP_000179633	DNA topoisomerase I [Streptococcus pneumoniae].	24.35	579	365	20	83	629	71	608	1e-21	109
rs:WP_029552434	DNA topoisomerase I [Thermocrinis sp. GBS].	26.10	498	307	16	83	564	57	509	1e-21	108
rs:WP_045345096	DNA topoisomerase I [Enterobacter cloacae].	24.79	589	376	21	76	633	82	634	1e-21	110
gpu:CP009505_1773	DNA topoisomerase I [Methanosarcina sp. MTP4]	22.96	575	363	24	90	629	95	624	2e-21	110
rs:WP_035145808	DNA topoisomerase I [Lactobacillus sakei].	24.13	572	371	17	90	629	68	608	2e-21	109
rs:WP_023944170	DNA topoisomerase I [Streptococcus mitis].	24.35	579	365	21	83	629	71	608	2e-21	109
rs:WP_006076577	DNA topoisomerase I [Halococcus saccharolyticus].	21.97	651	430	23	1	616	1	608	2e-21	110
rs:WP_043901710	DNA topoisomerase I [Streptococcus sp. DORA_10].	24.35	579	365	21	83	629	56	593	2e-21	109
rs:WP_029173296	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	2e-21	109
rs:WP_042751276	DNA topoisomerase I [Streptococcus mitis].	24.35	579	365	21	83	629	71	608	2e-21	109
rs:WP_039125636	DNA topoisomerase I [Francisella guangzhouensis].	26.63	612	363	26	55	616	29	604	2e-21	110
rs:WP_011022481	DNA topoisomerase I [Methanosarcina acetivorans].	25.10	478	308	20	188	646	196	642	2e-21	110
rs:WP_029658312	DNA topoisomerase I [Streptococcus pneumoniae].	23.70	578	370	18	83	629	53	590	2e-21	109
rs:WP_013114828	DNA topoisomerase I [Brachyspira murdochii].	23.88	670	398	23	3	629	27	627	2e-21	109
rs:WP_000774786	DNA topoisomerase 1 [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	2e-21	109
rs:WP_034550064	DNA topoisomerase I [Carnobacterium funditum].	24.35	575	366	19	90	630	68	607	2e-21	109
tr:W1UK62_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.35	579	365	21	83	629	124	661	2e-21	110
rs:WP_018365968	DNA topoisomerase I [Streptococcus didelphis].	23.50	583	368	18	83	630	88	627	2e-21	109
rs:WP_006810845	MULTISPECIES: topoisomerase I [Enterobacter].	24.06	586	384	18	76	633	82	634	2e-21	110
rs:WP_021873408	DNA topoisomerase [Firmicutes bacterium CAG:822].	24.28	659	400	26	3	629	5	596	2e-21	109
rs:WP_020005517	DNA topoisomerase I [Brachyspira innocens].	23.99	667	401	23	3	629	29	629	2e-21	109
rs:WP_043933337	DNA topoisomerase I [Bacillus sp. EB01].	25.14	553	357	20	105	629	82	605	2e-21	109
rs:WP_022388599	DNA topoisomerase [Ruminococcus obeum CAG:39].	23.80	563	351	21	90	616	67	587	2e-21	109
rs:WP_010237231	DNA topoisomerase I [Citromicrobium bathyomarinum].	23.10	658	410	21	1	619	1	601	2e-21	110
rs:WP_016265142	DNA topoisomerase I [Lactobacillus sakei].	24.13	572	371	17	90	629	68	608	2e-21	109
rs:WP_016312454	DNA topoisomerase I [Paenibacillus barengoltzii].	24.83	584	375	22	88	636	62	616	2e-21	109
rs:WP_022189573	DNA topoisomerase [Ruminococcus sp. CAG:177].	23.76	585	362	20	76	616	52	596	2e-21	109
rs:WP_011962037	topoisomerase I [Haemophilus influenzae].	25.47	475	296	14	187	633	196	640	2e-21	110
rs:WP_000179626	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.14	580	365	22	83	629	71	608	2e-21	109
rs:WP_000179661	DNA topoisomerase I [Streptococcus mitis].	24.35	579	365	21	83	629	71	608	2e-21	109
rs:WP_018300335	hypothetical protein [Fangia hongkongensis].	23.84	667	416	25	3	629	5	619	2e-21	110
rs:WP_001886798	topoisomerase I [Vibrio cholerae].	24.12	597	373	19	75	633	87	641	2e-21	110
rs:WP_002952543	TopA [Campylobacter showae].	25.05	507	325	15	100	578	72	551	2e-21	109
rs:WP_046522153	DNA topoisomerase I [Bacillus sp. SA2-6].	23.90	569	376	17	90	630	67	606	2e-21	109
rs:WP_032511243	DNA topoisomerase I [Streptococcus suis].	23.74	577	372	18	83	629	72	610	2e-21	109
rs:WP_000179630	DNA topoisomerase I [Streptococcus pneumoniae].	24.35	579	365	20	83	629	71	608	2e-21	109
rs:WP_000179635	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	71	608	2e-21	109
rs:WP_006429603	DNA topoisomerase I [Natrinema versiforme].	22.58	691	435	26	1	642	1	640	2e-21	110
gpu:CP009511_1531	DNA topoisomerase I [Methanosarcina mazei SarPi]	24.22	673	417	31	1	629	1	624	2e-21	109
rs:WP_010481170	DNA topoisomerase I [[Pseudomonas] geniculata].	24.91	578	336	20	3	538	5	526	2e-21	110
rs:WP_018250549	DNA topoisomerase I [Sphingomonas melonis].	23.05	668	421	23	1	629	1	614	2e-21	110
rs:WP_042991232	hypothetical protein, partial [Bifidobacterium adolescentis].	31.17	231	139	3	467	677	58	288	2e-21	106
rs:WP_005644977	topoisomerase I [Haemophilus haemolyticus].	24.95	473	301	13	187	633	196	640	2e-21	110
rs:WP_023946902	DNA topoisomerase I [Streptococcus mitis].	24.35	579	365	21	83	629	71	608	2e-21	109
rs:WP_028539393	DNA topoisomerase I [Paenibacillus sp. J14].	24.83	584	375	22	88	636	62	616	2e-21	109
tr:X8HMV1_9FUSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.75	695	432	22	2	671	9	637	2e-21	109
rs:WP_008527508	DNA topoisomerase I [Halorhabdus tiamatea].	22.17	672	402	29	1	616	1	607	2e-21	110
rs:WP_029662309	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	71	608	2e-21	109
rs:WP_017668615	hypothetical protein [Sandarakinorhabdus sp. AAP62].	24.96	685	393	31	1	629	1	620	2e-21	110
rs:WP_006885830	DNA topoisomerase I [Halosimplex carlsbadense].	24.41	553	342	22	1	521	1	509	2e-21	110
tr:T3QN90_PEPDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.93	560	332	21	154	647	1	532	2e-21	108
rs:WP_044765802	DNA topoisomerase I [Streptococcus suis].	23.74	577	372	19	83	629	72	610	2e-21	109
rs:WP_020445669	DNA topoisomerase I [Salinarchaeum sp. Harcht-Bsk1].	21.84	751	436	31	1	661	1	690	2e-21	110
gp:AJ938182_1074	DNA topoisomerase I [Staphylococcus aureus RF122]	24.65	568	369	17	90	629	69	605	2e-21	109
rs:WP_007044609	DNA topoisomerase I [Methanotorris formicicus].	25.77	617	367	23	1	581	2	563	2e-21	109
rs:WP_038033385	MULTISPECIES: DNA topoisomerase I [Thermotoga].	25.58	649	361	24	2	616	7	567	2e-21	109
sp:TOP1_STAAB	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.65	568	369	17	90	629	67	603	2e-21	109
rs:WP_039099413	DNA topoisomerase I [Lactobacillus curvatus].	23.95	572	372	17	90	629	68	608	2e-21	109
rs:WP_044971912	DNA topoisomerase I [Clostridiaceae bacterium MS3].	24.56	570	342	20	90	616	67	591	2e-21	109
rs:WP_021659817	DNA topoisomerase I [Clostridium sp. ATCC 29733].	23.93	631	398	24	83	674	59	646	2e-21	109
rs:WP_033659063	hypothetical protein [Enterococcus faecium].	34.09	176	110	3	41	210	2	177	2e-21	103
rs:WP_024417185	DNA topoisomerase I [Streptococcus suis].	23.53	578	372	19	83	629	72	610	2e-21	109
rs:WP_031789231	DNA topoisomerase I, partial [Staphylococcus aureus].	24.52	571	366	18	90	629	67	603	2e-21	109
rs:WP_011374691	DNA topoisomerase I [Lactobacillus sakei].	24.13	572	371	17	90	629	68	608	2e-21	109
rs:WP_035547526	DNA topoisomerase I, partial [Halobacillus sp. BBL2006].	25.96	570	349	22	103	635	80	613	2e-21	109
rs:WP_024392292	DNA topoisomerase I [Streptococcus suis].	23.74	577	372	19	83	629	72	610	2e-21	109
rs:WP_000179669	DNA topoisomerase I [Streptococcus sp. oral taxon 071].	24.18	579	366	21	83	629	71	608	2e-21	109
rs:WP_020902794	DNA topoisomerase I [Streptococcus mitis].	24.35	579	365	21	83	629	71	608	2e-21	109
rs:WP_000179665	DNA topoisomerase I [Streptococcus oralis].	24.18	579	366	21	83	629	71	608	2e-21	109
rs:WP_042253559	hypothetical protein [Lactobacillus brevis].	23.97	680	445	26	44	682	46	694	2e-21	109
rs:WP_000774785	DNA topoisomerase 1 [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	2e-21	109
rs:WP_000179664	DNA topoisomerase I [Streptococcus mitis].	24.35	579	365	21	83	629	71	608	2e-21	109
rs:WP_041262638	DNA topoisomerase I [Flexistipes sinusarabici].	24.96	597	375	20	88	644	59	622	2e-21	109
gpu:CP011528_1102	DNA topoisomerase I [Staphylococcus aureus]	23.90	569	372	16	90	629	67	603	2e-21	109
rs:WP_035442137	hypothetical protein [Bacillus sp. JCM 19046].	36.18	199	121	4	30	222	4	202	2e-21	104
rs:WP_000179655	DNA topoisomerase I [Streptococcus mitis].	24.35	579	365	21	83	629	71	608	2e-21	109
tr:F8XQU4_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	25.22	559	324	18	1	528	1	496	2e-21	108
rs:WP_017554457	DNA topoisomerase I [Bacillus coagulans].	24.47	568	356	22	105	635	82	613	2e-21	109
rs:WP_008457790	DNA topoisomerase I [Natrinema gari].	21.82	715	457	26	1	661	1	667	2e-21	109
rs:WP_041497609	DNA topoisomerase I, partial [Staphylococcus aureus].	24.65	568	369	17	90	629	27	563	2e-21	109
rs:WP_045607034	DNA topoisomerase I [Streptococcus mitis].	24.35	579	365	21	83	629	71	608	2e-21	109
gp:CP001996_1224	DNA topoisomerase I [Staphylococcus aureus subsp. aureus ED133]	24.65	568	369	17	90	629	69	605	2e-21	109
rs:WP_007739277	DNA topoisomerase I [Halococcus thailandensis].	22.01	718	452	28	1	661	1	667	2e-21	109
rs:WP_031418983	DNA topoisomerase I [Lysinibacillus sphaericus].	24.10	556	364	16	103	629	80	606	2e-21	109
rs:WP_000774791	DNA topoisomerase I [Staphylococcus aureus].	24.52	571	366	18	90	629	67	603	2e-21	109
gpu:CP009528_1551	DNA topoisomerase I [Methanosarcina barkeri MS]	24.68	462	295	18	188	629	196	624	2e-21	109
rs:WP_002416968	toprim domain protein, partial [Enterococcus faecalis].	35.12	205	111	7	3	192	4	201	2e-21	103
rs:XP_008860486	DNA topoisomerase domain containing protein [Entamoeba nuttalli P19].	24.42	516	327	16	105	589	114	597	2e-21	109
rs:WP_018132573	hypothetical protein [Effusibacillus pohliae].	24.07	565	355	18	88	614	62	590	2e-21	109
rs:WP_005603755	DNA topoisomerase I [Butyrivibrio crossotus].	25.28	629	367	24	90	671	67	639	2e-21	109
rs:WP_000445593	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	53	590	2e-21	109
rs:WP_046720801	DNA topoisomerase I [Bacillus coagulans].	24.47	568	356	22	105	635	82	613	2e-21	109
rs:WP_027090882	DNA topoisomerase I [Cohnella thermotolerans].	25.00	588	366	23	88	635	62	614	2e-21	109
rs:WP_021091905	DNA topoisomerase I [Campylobacter concisus].	24.72	530	343	16	77	578	50	551	2e-21	109
rs:WP_033680386	DNA topoisomerase I [Streptococcus mitis].	24.53	579	364	21	83	629	71	608	2e-21	109
tr:A0A078DBQ5_BRANA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.80	614	408	20	3	586	8	585	2e-21	109
rs:WP_043044512	DNA topoisomerase 1 [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	2e-21	109
rs:WP_005427273	DNA topoisomerase I [[Ruminococcus] obeum].	23.80	563	351	21	90	616	67	587	2e-21	109
rs:WP_010544015	DNA topoisomerase I [Sphingomonas elodea].	23.65	668	417	25	1	629	1	614	2e-21	109
tr:C7GH17_9FIRM	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EEU98883.1};	40.28	144	69	5	1	137	1	134	2e-21	103
rs:WP_013625429	DNA topoisomerase I [Syntrophobotulus glycolicus].	23.67	714	432	29	3	675	5	646	2e-21	109
tr:A0A0E1X6A0_STAAU	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EFH94907.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFH94907.1};	24.52	571	366	18	90	629	69	605	2e-21	109
rs:WP_015763957	DNA topoisomerase I [Halomicrobium mukohataei].	24.01	658	407	29	1	616	1	607	2e-21	109
rs:WP_000774784	DNA topoisomerase 1 [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	2e-21	109
rs:WP_031788381	DNA topoisomerase I [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	2e-21	109
rs:WP_034606018	hypothetical protein, partial [Chitinimonas koreensis].	23.10	606	378	19	55	614	17	580	2e-21	109
rs:WP_045181206	DNA topoisomerase I [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	2e-21	109
rs:WP_000246896	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	71	608	2e-21	109
rs:WP_032843600	DNA topoisomerase I [Fusobacterium nucleatum].	25.32	616	375	19	2	589	9	567	2e-21	109
rs:WP_000179682	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	71	608	2e-21	109
rs:WP_010130561	topoisomerase I [Microbulbifer agarilyticus].	23.17	630	423	16	72	673	87	683	2e-21	109
rs:WP_014547714	DNA topoisomerase I [Francisella tularensis].	25.80	597	374	20	74	629	51	619	2e-21	109
rs:WP_031865838	DNA topoisomerase 1 [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	2e-21	109
rs:WP_006575107	DNA topoisomerase I [Pseudoflavonifractor capillosus].	23.68	570	362	16	83	616	61	593	2e-21	109
rs:WP_016360252	MULTISPECIES: DNA topoisomerase I [Clostridiales].	24.56	570	342	20	90	616	67	591	2e-21	109
rs:WP_000179680	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	71	608	2e-21	109
rs:WP_000179642	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	71	608	2e-21	109
rs:WP_000774783	DNA topoisomerase I [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	2e-21	109
rs:WP_000179641	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	71	608	2e-21	109
rs:WP_033868999	DNA topoisomerase 1 [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	2e-21	109
rs:WP_015570386	DNA topoisomerase I [Enterobacter cloacae].	24.36	587	381	20	76	633	82	634	2e-21	109
rs:WP_000179674	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	71	608	2e-21	109
rs:WP_013969129	DNA topoisomerase I [Treponema caldaria].	22.94	667	407	21	3	629	15	614	2e-21	109
rs:WP_014517453	DNA topoisomerase I [Campylobacter jejuni].	25.52	529	334	16	81	579	55	553	2e-21	109
tr:A0A090LVT9_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.65	568	369	17	90	629	69	605	2e-21	109
rs:WP_024055748	DNA topoisomerase, partial [Streptococcus parasanguinis].	25.74	505	309	22	154	629	15	482	2e-21	108
rs:WP_038892183	DNA topoisomerase III, partial [Vibrio campbellii].	27.86	341	212	14	1	317	1	331	2e-21	106
gp:CP010526_1201	DNA topoisomerase I [Staphylococcus aureus subsp. aureus ST772-MRSA-V]	24.65	568	369	17	90	629	69	605	2e-21	109
gp:HE983624_851	DNA topoisomerase I [Streptococcus pneumoniae SPNA45]	23.88	578	369	18	83	629	19	556	2e-21	108
rs:WP_031911407	DNA topoisomerase I [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	2e-21	109
rs:WP_000774792	DNA topoisomerase I [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	2e-21	109
rs:WP_000179636	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	71	608	2e-21	109
tr:B2IPL8_STRPS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.88	578	369	18	83	629	77	614	2e-21	109
rs:WP_031826017	DNA topoisomerase I [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	2e-21	109
rs:WP_029052236	DNA topoisomerase I, partial [Staphylococcus aureus].	24.47	568	370	17	90	629	67	603	2e-21	108
rs:WP_027110232	DNA topoisomerase I [Lachnospiraceae bacterium NC2008].	25.18	568	339	19	90	616	67	589	2e-21	109
rs:WP_031765830	DNA topoisomerase 1 [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	2e-21	109
gpu:LN847353_1153	DNA topoisomerase I [Streptococcus pneumoniae]	23.88	578	369	18	83	629	71	608	2e-21	109
tr:F8E529_FLESM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.96	597	375	20	88	644	77	640	2e-21	109
rs:WP_028246918	DNA topoisomerase I [Pseudobutyrivibrio ruminis].	23.73	611	394	20	36	616	22	590	2e-21	109
rs:WP_000774782	DNA topoisomerase I [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	2e-21	109
rs:WP_000246895	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	71	608	2e-21	109
rs:WP_000179638	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	71	608	2e-21	109
rs:WP_012635699	DNA topoisomerase I [Halothermothrix orenii].	23.77	669	395	25	3	629	9	604	2e-21	109
rs:XP_008206402	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Nasonia vitripennis].	24.14	464	303	11	188	630	157	592	3e-21	109
tr:W8UYB5_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.65	568	369	17	90	629	69	605	3e-21	109
rs:WP_032958266	DNA topoisomerase I [Stenotrophomonas maltophilia].	24.91	578	336	20	3	538	5	526	3e-21	109
rs:XP_012455604	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Gossypium raimondii].	24.78	565	350	23	54	586	24	545	3e-21	109
rs:WP_014704495	DNA topoisomerase I [Methylophaga frappieri].	24.26	742	435	36	2	687	4	674	3e-21	109
rs:WP_027825571	DNA topoisomerase I [Lactobacillus psittaci].	24.56	570	339	22	103	629	83	604	3e-21	109
rs:WP_042942923	DNA topoisomerase III, partial [Klebsiella pneumoniae].	35.68	213	119	8	190	385	1	212	3e-21	103
rs:WP_029178045	DNA topoisomerase I [Streptococcus suis].	23.57	577	373	18	83	629	72	610	3e-21	109
rs:WP_032840878	DNA topoisomerase I [Fusobacterium sp. CM21].	25.28	617	374	20	2	589	9	567	3e-21	109
rs:WP_031844621	DNA topoisomerase I [Staphylococcus aureus].	24.70	583	379	18	90	643	67	618	3e-21	108
rs:WP_000445594	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	53	590	3e-21	108
rs:WP_000774776	DNA topoisomerase 1 [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	3e-21	108
tr:A4N5H6_HAEIF	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.16	473	300	13	187	633	196	640	3e-21	109
rs:WP_031838416	DNA topoisomerase I [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	3e-21	108
rs:WP_000179639	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	71	608	3e-21	108
rs:WP_042456355	DNA topoisomerase I [Bacillus sp. FF4].	24.20	566	361	20	105	635	82	614	3e-21	108
rs:WP_021725319	DNA topoisomerase I [Olsenella profusa].	22.96	649	408	25	61	664	111	712	3e-21	109
rs:WP_039081779	DNA topoisomerase I [Gallibacterium anatis].	23.38	586	392	14	74	633	86	640	3e-21	109
rs:WP_044346183	DNA topoisomerase I [Desulfarculus sp. SPR].	24.55	672	401	25	3	631	5	613	3e-21	109
rs:WP_038041729	hypothetical protein, partial [Thermodesulfobacterium hveragerdense].	26.83	574	345	20	2	557	4	520	3e-21	108
rs:WP_016399457	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	71	608	3e-21	108
rs:WP_020434731	DNA topoisomerase [Clostridium sp. CAG:1000].	25.53	705	428	27	3	679	4	639	3e-21	108
rs:WP_029653650	DNA topoisomerase I [Marinobacter daepoensis].	23.75	640	410	22	72	673	86	685	3e-21	109
sp:TOP1_STAAM	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.65	568	369	17	90	629	67	603	3e-21	108
rs:WP_031895351	DNA topoisomerase 1 [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	3e-21	108
rs:WP_044131834	DNA topoisomerase I, partial [Staphylococcus aureus].	24.47	568	370	17	90	629	67	603	3e-21	108
rs:WP_020998619	DNA topoisomerase I [Streptococcus intermedius].	23.91	573	375	19	83	629	70	607	3e-21	108
tr:R9RD65_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.85	619	368	22	2	589	9	567	3e-21	109
rs:WP_040653704	DNA topoisomerase I, partial [Oribacterium sp. oral taxon 078].	23.27	649	399	22	3	616	5	589	3e-21	108
rs:WP_043065995	DNA topoisomerase I [Aneurinibacillus migulanus].	24.40	582	376	23	88	635	62	613	3e-21	108
rs:WP_044345697	DNA topoisomerase I [Haemophilus influenzae].	25.84	476	293	16	187	633	196	640	3e-21	109
rs:XP_652633	DNA topoisomerase III [Entamoeba histolytica HM-1:IMSS].	25.20	504	320	17	105	580	114	588	3e-21	109
rs:WP_022115579	DNA topoisomerase [Clostridium sp. CAG:524].	24.24	656	404	22	3	629	4	595	3e-21	108
rs:WP_022781580	DNA topoisomerase I [Lachnospiraceae bacterium NK4A136].	25.00	572	335	20	90	616	67	589	3e-21	108
rs:WP_015902075	DNA topoisomerase I [Nautilia profundicola].	25.15	660	393	24	3	629	5	596	3e-21	108
rs:WP_032129673	DNA topoisomerase I [Stenotrophomonas maltophilia].	24.91	578	336	20	3	538	5	526	3e-21	109
rs:WP_006702673	DNA topoisomerase I [Granulicatella elegans].	25.39	575	355	25	90	629	68	603	3e-21	108
rs:XP_001606777	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Nasonia vitripennis].	24.14	464	303	11	188	630	210	645	3e-21	109
tr:D4CLC3_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.27	649	399	22	3	616	5	589	3e-21	108
rs:WP_033867932	DNA topoisomerase I [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	3e-21	108
rs:WP_041346435	topoisomerase I, partial [Oenococcus oeni].	26.25	240	170	3	347	581	12	249	3e-21	105
rs:WP_032878736	DNA topoisomerase I [Fusobacterium nucleatum].	25.17	604	369	20	2	580	9	554	3e-21	109
rs:WP_031807729	DNA topoisomerase 1 [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	3e-21	108
tr:X1DF39_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_C00312 {ECO:0000313|EMBL:GAH19441.1}; Flags: Fragment;	26.22	534	332	22	1	511	1	495	3e-21	107
rs:WP_004269684	DNA topoisomerase I [Streptococcus mitis].	24.01	579	367	20	83	629	71	608	3e-21	108
rs:WP_004737437	topoisomerase I [Vibrio splendidus].	24.04	599	373	18	74	633	84	639	3e-21	109
rs:WP_019722027	DNA topoisomerase I [Bacillus coagulans].	24.30	568	357	22	105	635	82	613	3e-21	108
rs:WP_000774779	DNA topoisomerase I [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	3e-21	108
rs:WP_000774778	DNA topoisomerase I [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	3e-21	108
rs:WP_031894812	DNA topoisomerase 1 [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	3e-21	108
tr:C3WNT3_FUSNV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.32	616	375	19	2	589	12	570	3e-21	108
rs:WP_021151602	DNA topoisomerase III [Streptococcus sp. HSISS3].	25.77	392	257	14	266	625	120	509	3e-21	108
rs:WP_042833103	DNA topoisomerase I [Thermoanaerobacter sp. YS13].	24.92	590	344	21	90	629	67	607	3e-21	108
gp:CP010941_1149	DNA topoisomerase I [Staphylococcus aureus]	24.65	568	369	17	90	629	67	603	3e-21	108
rs:WP_042902188	DNA topoisomerase I [Streptococcus oralis].	24.14	580	365	22	83	629	71	608	3e-21	108
rs:WP_000445595	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	53	590	3e-21	108
rs:WP_032092645	DNA topoisomerase I [Necropsobacter rosorum].	24.66	596	366	19	77	633	89	640	3e-21	109
rs:WP_046949842	DNA topoisomerase I [Haemophilus haemolyticus].	25.37	477	294	14	187	633	196	640	3e-21	109
rs:WP_000179653	DNA topoisomerase I [Streptococcus mitis].	24.05	578	368	19	83	629	71	608	3e-21	108
rs:WP_000179622	DNA topoisomerase I [Streptococcus oralis].	23.97	580	366	22	83	629	71	608	3e-21	108
rs:WP_016398196	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	71	608	3e-21	108
rs:WP_035181783	DNA topoisomerase I [Bacillus coagulans].	24.47	568	356	22	105	635	82	613	3e-21	108
rs:WP_006556648	DNA topoisomerase I [Veillonella ratti].	23.56	573	359	20	95	629	129	660	3e-21	108
rs:WP_024383462	DNA topoisomerase I [Streptococcus suis].	23.57	577	373	18	83	629	72	610	3e-21	108
rs:WP_014648569	DNA topoisomerase I [Stenotrophomonas maltophilia].	24.91	578	336	20	3	538	5	526	3e-21	109
rs:WP_000774777	DNA topoisomerase 1 [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	3e-21	108
rs:WP_033964691	DNA topoisomerase I [Sphingomonas sp. Ant H11].	23.45	678	406	26	1	629	1	614	3e-21	109
rs:WP_032839643	DNA topoisomerase I [Fusobacterium nucleatum].	25.85	619	368	22	2	589	12	570	3e-21	108
rs:WP_002355040	toprim domain protein, partial [Enterococcus faecium].	33.52	176	111	3	41	210	27	202	3e-21	103
rs:WP_034161568	DNA topoisomerase I [Sphingomonas sp. ERG5].	23.27	666	422	23	1	629	1	614	3e-21	109
rs:WP_031790580	DNA topoisomerase I [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	3e-21	108
rs:WP_000774781	DNA topoisomerase I [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	3e-21	108
rs:WP_010209953	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	29.00	231	145	5	2	223	1	221	3e-21	103
rs:XP_010522284	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Tarenaya hassleriana].	24.07	619	397	24	3	586	8	588	3e-21	109
rs:WP_034569661	DNA topoisomerase I [Carnobacterium divergens].	24.17	571	370	18	90	629	68	606	3e-21	108
tr:C0AQN3_9ENTR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEG87686.1};	36.20	163	104	0	419	581	24	186	3e-21	103
rs:WP_006185387	DNA topoisomerase I [Natrinema pallidum].	21.64	730	457	26	1	661	1	684	3e-21	109
rs:WP_041461236	DNA topoisomerase I [Fusobacterium nucleatum].	25.85	619	368	22	2	589	12	570	3e-21	108
rs:WP_008730397	DNA topoisomerase I [Brachyspira hampsonii].	24.30	679	386	25	2	629	26	627	3e-21	108
tr:A0A0B3AFU7_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.02	669	430	22	3	631	5	628	3e-21	108
rs:WP_000179678	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	71	608	3e-21	108
rs:WP_004052455	DNA topoisomerase I [Eubacterium plexicaudatum].	24.33	563	351	16	90	616	67	590	3e-21	108
rs:XP_009371098	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Pyrus x bretschneideri].	22.44	664	447	20	3	631	7	637	3e-21	109
rs:WP_044310449	DNA topoisomerase III, partial [Pseudomonas syringae].	31.78	236	145	5	101	321	1	235	3e-21	104
rs:WP_033677361	DNA topoisomerase I [Streptococcus mitis].	24.35	579	365	21	83	629	71	608	3e-21	108
rs:WP_002322645	DNA topoisomerase III, partial [Enterococcus faecium].	26.15	325	221	7	361	667	1	324	3e-21	105
rs:WP_031914761	DNA topoisomerase I [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	3e-21	108
rs:WP_033629621	DNA topoisomerase I [Streptococcus oralis].	24.18	579	366	21	83	629	71	608	3e-21	108
rs:WP_001548566	DNA topoisomerase I [Staphylococcus aureus].	24.47	568	370	17	90	629	69	605	3e-21	108
rs:WP_031872092	DNA topoisomerase I [Staphylococcus aureus].	24.47	568	370	17	90	629	67	603	3e-21	108
rs:WP_031770059	DNA topoisomerase I [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	3e-21	108
rs:WP_040033789	DNA topoisomerase I [Haemophilus influenzae].	25.16	473	300	13	187	633	196	640	3e-21	109
rs:WP_013859077	DNA topoisomerase I [Bacillus coagulans].	24.47	568	356	22	105	635	82	613	3e-21	108
rs:WP_032478146	DNA topoisomerase I [Vibrio cholerae].	24.46	605	361	22	75	633	87	641	3e-21	109
rs:WP_008685770	DNA topoisomerase I [Desulfovibrio sp. 3_1_syn3].	23.17	643	385	21	1	613	1	564	3e-21	108
rs:WP_044773639	DNA topoisomerase I [Streptococcus suis].	23.66	579	370	19	83	629	72	610	3e-21	108
rs:WP_023370336	DNA topoisomerase I [Streptococcus suis].	23.66	579	370	19	83	629	72	610	3e-21	108
rs:WP_011961921	topoisomerase I [Haemophilus influenzae].	25.26	475	297	14	187	633	196	640	3e-21	109
rs:WP_012429273	DNA topoisomerase I [Francisella tularensis].	25.29	597	377	20	74	629	51	619	3e-21	108
rs:WP_024390904	DNA topoisomerase I [Streptococcus suis].	23.83	579	369	19	83	629	72	610	3e-21	108
tr:U7TA88_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.85	619	368	22	2	589	9	567	3e-21	108
rs:WP_019338924	DNA topoisomerase I [Stenotrophomonas maltophilia].	24.74	578	337	20	3	538	5	526	3e-21	108
rs:WP_031882457	DNA topoisomerase 1 [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	3e-21	108
rs:WP_032823063	DNA topoisomerase I, partial [Haemophilus influenzae].	25.16	473	300	13	187	633	196	640	3e-21	108
rs:WP_012447839	DNA topoisomerase I [Natranaerobius thermophilus].	26.24	564	347	20	83	616	60	584	3e-21	108
rs:WP_027894204	DNA topoisomerase I [Meiothermus chliarophilus].	23.96	576	354	20	76	616	54	580	3e-21	108
rs:WP_005414607	DNA topoisomerase I [Stenotrophomonas maltophilia].	24.74	578	337	20	3	538	5	526	3e-21	108
rs:WP_044755138	DNA topoisomerase I [Streptococcus suis].	23.66	579	370	19	83	629	72	610	3e-21	108
rs:WP_005411198	DNA topoisomerase I [Stenotrophomonas maltophilia].	24.74	578	337	20	3	538	5	526	3e-21	108
tr:D6BDD4_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.85	619	368	22	2	589	12	570	4e-21	108
rs:WP_008700964	DNA topoisomerase I [Fusobacterium nucleatum].	25.85	619	368	22	2	589	12	570	4e-21	108
tr:A0A098EWQ6_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.23	553	364	19	105	630	82	606	4e-21	108
tr:A0A077UHQ3_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.82	568	368	17	90	629	69	605	4e-21	108
rs:WP_031925401	DNA topoisomerase 1 [Staphylococcus aureus].	24.47	568	370	17	90	629	67	603	4e-21	108
rs:WP_009182186	DNA topoisomerase I [Desulfovibrio sp. FW1012B].	24.54	599	365	22	79	640	53	601	4e-21	108
rs:WP_031921185	DNA topoisomerase 1 [Staphylococcus aureus].	24.47	568	370	17	90	629	67	603	4e-21	108
rs:WP_031891318	DNA topoisomerase 1 [Staphylococcus aureus].	24.47	568	370	17	90	629	67	603	4e-21	108
rs:WP_016548180	DNA topoisomerase I [Leptospira fainei].	22.81	675	407	21	2	630	3	609	4e-21	108
rs:WP_018167332	DNA topoisomerase I [Streptococcus minor].	23.40	577	374	19	83	629	76	614	4e-21	108
rs:WP_018625461	topoisomerase I [Kangiella aquimarina].	25.42	598	362	22	76	633	94	647	4e-21	108
tr:C7GH19_9FIRM	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EEU98885.1};	26.55	339	225	8	350	671	1	332	4e-21	105
rs:WP_045336485	DNA topoisomerase I [Enterobacter cloacae].	23.89	586	385	18	76	633	82	634	4e-21	108
tr:A0A063ZJV9_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.44	731	451	31	1	661	1	685	4e-21	108
rs:WP_021789620	hypothetical protein [Thermoplasmatales archaeon Gpl].	26.28	605	344	25	3	564	9	554	4e-21	108
tr:A0A061NCY7_9BACL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.44	577	366	22	90	629	60	603	4e-21	108
rs:WP_044679670	DNA topoisomerase I [Streptococcus suis].	23.80	584	363	20	83	629	72	610	4e-21	108
rs:WP_024400616	DNA topoisomerase I [Streptococcus suis].	23.57	577	373	18	83	629	72	610	4e-21	108
rs:WP_024388699	DNA topoisomerase I [Streptococcus suis].	23.66	579	370	19	83	629	72	610	4e-21	108
rs:WP_012512224	DNA topoisomerase I [Stenotrophomonas maltophilia].	25.13	581	331	21	3	538	5	526	4e-21	108
sp:TOP1_STAA3	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.47	568	370	17	90	629	67	603	4e-21	108
rs:WP_000179681	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	71	608	4e-21	108
tr:D4LWC7_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.60	569	339	22	90	616	67	587	4e-21	108
rs:WP_044895581	DNA topoisomerase I [Bacillus alveayuensis].	24.46	560	366	20	105	635	82	613	4e-21	108
rs:WP_039089898	DNA topoisomerase I [Gallibacterium anatis].	23.86	591	383	17	74	633	86	640	4e-21	108
rs:WP_013525788	topoisomerase I [Haemophilus influenzae].	25.26	475	297	14	187	633	196	640	4e-21	108
gpu:CP009513_1559	DNA topoisomerase I [Methanosarcina mazei LYC]	24.22	669	422	29	1	629	1	624	4e-21	108
rs:WP_014624573	DNA topoisomerase I [Spirochaeta thermophila].	25.46	593	363	21	89	644	72	622	4e-21	108
rs:WP_039168906	DNA topoisomerase I [Gallibacterium anatis].	23.86	591	383	17	74	633	86	640	4e-21	108
rs:WP_045611818	DNA topoisomerase I [Streptococcus mitis].	24.35	579	365	21	83	629	71	608	4e-21	108
rs:WP_022069750	DNA topoisomerase [Fusobacterium sp. CAG:649].	25.85	619	368	22	2	589	9	567	4e-21	108
rs:WP_008181277	DNA topoisomerase I [Bacillus sp. B14905].	24.10	556	364	16	103	629	80	606	4e-21	108
rs:WP_042610841	DNA topoisomerase I [Haemophilus influenzae].	25.26	475	297	14	187	633	196	640	4e-21	108
tr:A0A072NRK6_BACAZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.10	556	361	18	105	629	106	631	4e-21	108
rs:WP_013495388	DNA topoisomerase I [Thermaerobacter marianensis].	22.78	562	379	15	83	616	60	594	4e-21	108
rs:WP_044771417	DNA topoisomerase I [Streptococcus suis].	24.14	584	361	20	83	629	72	610	4e-21	108
rs:WP_002455421	DNA topoisomerase I [Staphylococcus hominis].	25.95	555	352	21	103	629	80	603	4e-21	108
rs:WP_007152347	topoisomerase I [Marinobacter algicola].	24.66	596	379	20	72	633	86	645	4e-21	108
rs:WP_016800735	topoisomerase I [Vibrio cyclitrophicus].	23.71	603	370	19	74	633	84	639	4e-21	108
rs:WP_012775596	DNA topoisomerase I [Streptococcus suis].	23.57	577	373	18	83	629	72	610	4e-21	108
rs:WP_035193594	DNA topoisomerase I [Bacillus azotoformans].	24.10	556	361	18	105	629	82	607	4e-21	108
rs:XP_001950527	PREDICTED: DNA topoisomerase 3-alpha [Acyrthosiphon pisum].	24.88	643	385	25	29	619	74	670	4e-21	108
rs:WP_015711082	DNA topoisomerase I [Treponema azotonutricium].	26.63	567	340	22	100	629	91	618	4e-21	108
rs:WP_039158618	DNA topoisomerase I [Gallibacterium anatis].	23.86	591	383	17	74	633	86	640	4e-21	108
rs:WP_000520441	topoisomerase I [Vibrio sp. RC586].	23.82	613	375	20	57	633	85	641	4e-21	108
rs:WP_003856806	MULTISPECIES: topoisomerase I [Enterobacter cloacae complex].	23.89	586	385	18	76	633	82	634	4e-21	108
rs:WP_039096786	DNA topoisomerase I [Gallibacterium anatis].	23.86	591	383	17	74	633	86	640	4e-21	108
rs:WP_010437771	topoisomerase I [Vibrio cyclitrophicus].	23.71	603	370	19	74	633	84	639	4e-21	108
rs:WP_000179679	DNA topoisomerase I [Streptococcus pneumoniae].	23.88	578	369	18	83	629	71	608	4e-21	108
rs:WP_041900725	hypothetical protein, partial [Marinimicrobia bacterium SCGC AAA160-B08].	26.94	527	302	18	82	560	61	552	4e-21	108
rs:WP_031913953	DNA topoisomerase I [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	4e-21	108
rs:WP_028381135	DNA topoisomerase I [Legionella cherrii].	25.04	679	394	31	3	630	5	619	4e-21	108
rs:WP_007505175	DNA topoisomerase I [Caldalkalibacillus thermarum].	24.38	607	388	23	103	676	80	648	4e-21	108
rs:WP_044811425	DNA topoisomerase I [Streptococcus pneumoniae].	24.01	579	367	18	83	629	71	608	4e-21	108
gpu:CP009516_2375	DNA topoisomerase I [Methanosarcina horonobensis HB-1]	25.05	463	292	20	188	629	196	624	4e-21	108
tr:V7Z0V9_LACPN	SubName: Full=Topoisomerase I {ECO:0000313|EMBL:ETC79988.1};	26.92	234	164	3	353	581	2	233	5e-21	105
rs:WP_029599011	DNA topoisomerase I [Fusobacterium nucleatum].	25.85	619	368	22	2	589	12	570	5e-21	108
rs:XP_002321105	DNA topoisomerase family protein [Populus trichocarpa].	22.52	626	414	19	39	631	24	611	5e-21	108
rs:WP_012279897	DNA topoisomerase I [Francisella philomiragia].	26.13	597	372	22	74	629	51	619	5e-21	108
rs:WP_033617385	topoisomerase I, partial [Lactobacillus plantarum].	28.48	302	184	10	167	446	3	294	5e-21	105
rs:WP_038891121	DNA topoisomerase III, partial [Vibrio campbellii].	27.73	339	215	13	1	317	1	331	5e-21	105
rs:WP_033799838	DNA topoisomerase I, partial [Bacillus pseudomycoides].	30.74	283	183	10	3	276	5	283	5e-21	104
rs:WP_039142357	DNA topoisomerase I [Gallibacterium anatis].	23.86	591	383	17	74	633	86	640	5e-21	108
rs:WP_045335024	DNA topoisomerase I [Enterobacter cloacae].	24.79	589	376	21	76	633	82	634	5e-21	108
rs:WP_023168138	DNA topoisomerase III, partial [Salmonella enterica].	31.34	201	132	3	384	581	2	199	5e-21	103
rs:WP_041341774	DNA topoisomerase I [Dehalococcoides mccartyi].	25.07	674	387	26	2	624	4	610	5e-21	108
rs:WP_006091896	DNA topoisomerase I [Natronorubrum tibetense].	22.01	718	457	27	1	661	1	672	5e-21	108
rs:WP_031869532	DNA topoisomerase 1 [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	5e-21	108
gpu:CP009512_1612	DNA topoisomerase I [Methanosarcina mazei S-6]	24.22	673	417	31	1	629	1	624	5e-21	108
rs:WP_012901076	DNA topoisomerase I [Methanocella paludicola].	22.24	715	457	28	1	671	1	660	5e-21	108
rs:WP_044667700	DNA topoisomerase I [Streptococcus suis].	23.66	579	370	19	83	629	72	610	5e-21	108
rs:WP_020621258	DNA topoisomerase I [Cohnella laeviribosi].	25.30	589	363	24	88	635	62	614	5e-21	108
rs:WP_039106749	hypothetical protein [Lactobacillus brevis].	24.08	681	443	27	44	682	45	693	5e-21	108
rs:WP_006175684	topoisomerase I [Enterobacter cancerogenus].	24.63	601	362	22	76	633	82	634	5e-21	108
rs:WP_011227691	DNA topoisomerase I [Thermus thermophilus].	24.40	668	366	25	3	616	18	600	5e-21	108
rs:WP_031906744	DNA topoisomerase I [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	5e-21	108
rs:WP_000520434	topoisomerase I [Vibrio cholerae].	24.46	605	361	22	75	633	87	641	5e-21	108
rs:WP_029141585	DNA topoisomerase I [Bacillus coagulans].	24.30	568	357	22	105	635	82	613	5e-21	108
rs:WP_021774356	DNA topoisomerase I [Oribacterium sp. oral taxon 078].	23.27	649	399	22	3	616	5	589	5e-21	108
rs:WP_044769796	DNA topoisomerase I [Streptococcus suis].	23.66	579	370	19	83	629	72	610	5e-21	108
rs:XP_004502265	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Cicer arietinum].	23.27	666	436	21	3	631	7	634	5e-21	108
rs:WP_000774789	DNA topoisomerase I [Staphylococcus aureus].	24.47	568	370	17	90	629	67	603	5e-21	108
rs:WP_015413028	DNA topoisomerase I [Methanosarcina mazei].	24.33	674	415	31	1	629	1	624	5e-21	108
rs:WP_031914685	DNA topoisomerase 1 [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	5e-21	108
tr:A0A0C2LFM7_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.65	568	369	17	90	629	69	605	5e-21	108
rs:WP_016290460	DNA topoisomerase I [Lachnospiraceae bacterium 28-4].	23.67	638	389	21	90	658	67	675	5e-21	108
rs:WP_037593321	DNA topoisomerase III, partial [Sporosarcina sp. D27].	24.69	405	275	12	299	679	7	405	5e-21	105
rs:WP_009874238	topoisomerase I [Buchnera aphidicola].	24.73	566	360	16	74	614	79	603	5e-21	108
rs:WP_005706314	topoisomerase I [Haemophilus parahaemolyticus].	24.36	587	380	18	74	631	87	638	5e-21	108
rs:WP_022463897	DNA topoisomerase [Clostridium sp. CAG:277].	24.39	619	393	19	90	675	70	646	5e-21	108
tr:H3G0S0_PRIPA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.95	481	295	19	163	610	182	629	5e-21	108
rs:WP_042900774	DNA topoisomerase I [Streptococcus mitis].	24.35	579	365	21	83	629	71	608	5e-21	108
rs:WP_039145862	DNA topoisomerase I [Gallibacterium anatis].	23.86	591	383	17	74	633	86	640	5e-21	108
rs:WP_011252816	DNA topoisomerase I [Gluconobacter oxydans].	23.21	655	401	24	38	629	17	632	5e-21	108
rs:WP_022305903	DNA topoisomerase [Roseburia sp. CAG:380].	34.78	184	104	5	2	177	4	179	5e-21	103
rs:WP_046961026	DNA topoisomerase I [Dehalococcoides sp. UCH007].	25.07	674	387	26	2	624	4	610	5e-21	108
rs:WP_015052783	DNA topoisomerase I [Methanolobus psychrophilus].	24.27	684	421	31	1	640	1	631	5e-21	108
rs:WP_022029016	DNA topoisomerase [Clostridium sp. CAG:762].	24.02	662	398	25	3	629	5	596	5e-21	108
rs:WP_031929655	DNA topoisomerase 1 [Staphylococcus aureus].	24.47	568	370	17	90	629	67	603	5e-21	108
rs:WP_000774787	DNA topoisomerase 1 [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	5e-21	108
rs:WP_037537327	DNA topoisomerase I [Staphylococcus haemolyticus].	25.35	572	360	20	90	629	67	603	5e-21	108
rs:WP_033799363	DNA topoisomerase I, partial [Bacillus pseudomycoides].	31.47	286	177	10	3	276	5	283	5e-21	104
tr:A0A023X4A7_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.43	655	405	27	1	616	1	604	5e-21	108
rs:WP_026683990	DNA topoisomerase I [Bacillus coagulans].	24.30	568	357	22	105	635	82	613	5e-21	108
rs:WP_008488535	topoisomerase I [Idiomarina xiamenensis].	25.83	484	283	16	187	633	196	640	6e-21	108
rs:WP_000629137	hypothetical protein, partial [Escherichia coli].	30.60	281	176	5	176	442	3	278	6e-21	104
rs:WP_005837859	DNA topoisomerase I [Eubacterium saphenum].	23.73	670	411	20	2	636	12	616	6e-21	108
tr:K4XDU0_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.54	325	204	10	65	367	8	329	6e-21	105
rs:WP_027118545	DNA topoisomerase I [Lachnospiraceae bacterium YSB2008].	25.66	569	304	21	98	616	75	574	6e-21	107
rs:WP_044684533	DNA topoisomerase I [Streptococcus suis].	23.66	579	370	19	83	629	72	610	6e-21	108
rs:WP_024791993	DNA topoisomerase I [Lebetimonas sp. JS138].	25.61	660	390	27	3	629	5	596	6e-21	108
rs:WP_011034974	DNA topoisomerase I [Methanosarcina mazei].	24.36	669	421	29	1	629	1	624	6e-21	108
rs:WP_007236454	topoisomerase I [marine gamma proteobacterium HTCC2080].	23.81	609	372	19	60	631	89	642	6e-21	108
rs:WP_031868161	DNA topoisomerase I [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	6e-21	108
rs:WP_005631659	topoisomerase I [Haemophilus haemolyticus].	25.16	473	300	13	187	633	196	640	6e-21	108
rs:WP_013313691	DNA topoisomerase I [Spirochaeta thermophila].	25.46	593	363	21	89	644	72	622	6e-21	108
rs:WP_002349400	DNA topoisomerase, partial [Enterococcus faecium].	27.24	279	180	5	290	553	8	278	6e-21	103
rs:WP_045671983	DNA topoisomerase I [Paenibacillus beijingensis].	24.56	570	360	21	103	636	80	615	6e-21	108
rs:WP_021461512	topoisomerase I [Gallibacterium anatis].	23.86	591	383	17	74	633	86	640	6e-21	108
rs:WP_011110334	DNA topoisomerase I [Bacillus cereus].	23.93	560	369	20	105	635	52	583	6e-21	107
rs:WP_044337412	DNA topoisomerase I [Bacillus aquimaris].	24.60	569	364	21	100	635	77	613	6e-21	108
rs:WP_045992673	DNA topoisomerase I [Halomonas sp. S2151].	25.17	604	363	21	72	633	87	643	6e-21	108
rs:WP_044396592	DNA topoisomerase I [Bacillus subterraneus].	24.50	551	365	18	105	630	82	606	6e-21	107
rs:WP_040378997	DNA topoisomerase I, partial [Dethiobacter alkaliphilus].	25.91	579	352	21	90	630	67	606	6e-21	107
rs:WP_038289162	DNA topoisomerase I [[Clostridium] straminisolvens].	25.04	619	383	21	90	671	67	641	6e-21	108
rs:WP_009495774	DNA topoisomerase I [Campylobacter showae].	25.05	507	325	15	100	578	72	551	6e-21	107
rs:WP_020413102	topoisomerase I [Microbulbifer variabilis].	24.05	603	378	19	65	629	80	640	6e-21	108
rs:WP_044781401	DNA topoisomerase I [Streptococcus suis].	23.57	577	373	18	83	629	72	610	6e-21	107
rs:WP_010777005	hypothetical protein, partial [Enterococcus faecalis].	36.17	188	102	6	3	179	4	184	6e-21	102
rs:WP_017085853	topoisomerase I [Vibrio splendidus].	23.87	599	374	18	74	633	84	639	6e-21	108
rs:WP_016768417	topoisomerase I [Vibrio cyclitrophicus].	23.87	599	374	18	74	633	84	639	6e-21	108
rs:WP_040075361	DNA topoisomerase I [Enterobacteriaceae bacterium ATCC 29904].	24.16	592	387	18	73	633	74	634	6e-21	108
rs:WP_020250963	MULTISPECIES: hypothetical protein [unclassified Cloacimonetes].	27.62	583	345	23	83	629	60	601	6e-21	108
tr:K1R4T8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC44072.1}; Flags: Fragment;	27.13	317	209	6	374	670	4	318	6e-21	104
rs:WP_033798018	hypothetical protein [Bacillus mycoides].	34.52	197	113	8	3	193	5	191	6e-21	102
rs:WP_045333127	DNA topoisomerase I [Enterobacter cloacae].	23.89	586	385	18	76	633	82	634	6e-21	108
rs:WP_005368869	MULTISPECIES: DNA topoisomerase I [Methylomicrobium].	23.31	682	404	30	3	630	5	621	6e-21	108
rs:WP_019167868	DNA topoisomerase I [Staphylococcus intermedius].	25.13	573	360	22	90	629	67	603	6e-21	107
rs:YP_003446332	DNA topoisomerase I [Streptococcus mitis B6].	24.35	579	365	21	83	629	71	608	6e-21	107
sp:TOP1_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.65	568	369	17	90	629	67	603	6e-21	107
rs:WP_024404254	DNA topoisomerase I [Streptococcus suis].	23.70	578	372	19	83	629	72	611	6e-21	107
tr:G7ZMZ8_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.47	568	370	17	90	629	69	605	7e-21	107
rs:WP_009568636	DNA topoisomerase I [Streptococcus intermedius].	23.69	574	377	19	83	630	70	608	7e-21	107
rs:WP_007123236	DNA topoisomerase I [Lactobacillus antri].	24.44	577	357	24	90	629	92	626	7e-21	107
rs:WP_032642185	DNA topoisomerase I [Enterobacter sp. EGD-HP1].	24.09	602	364	23	76	633	82	634	7e-21	108
rs:WP_010931749	DNA topoisomerase I [Chlorobaculum tepidum].	24.50	604	367	19	76	629	63	627	7e-21	108
rs:WP_021002711	DNA topoisomerase I [Streptococcus intermedius].	23.69	574	377	19	83	630	70	608	7e-21	107
rs:XP_004989945	DNA topoisomerase [Salpingoeca rosetta].	22.22	612	395	20	3	571	6	579	7e-21	108
rs:WP_022272018	DNA topoisomerase [Eubacterium siraeum CAG:80].	25.56	630	383	24	82	671	58	641	7e-21	107
rs:WP_031533810	MULTISPECIES: DNA topoisomerase I [Bacteroides].	24.31	617	379	20	3	603	4	548	7e-21	108
rs:WP_011257487	DNA topoisomerase I [Xanthomonas oryzae].	24.61	573	344	20	3	538	5	526	7e-21	108
rs:WP_038441141	DNA topoisomerase I [Haemophilus influenzae].	25.26	475	297	14	187	633	196	640	7e-21	108
rs:WP_013780472	DNA topoisomerase I [Mahella australiensis].	24.82	556	356	20	90	616	67	589	7e-21	107
rs:WP_036208086	DNA topoisomerase I [Marinobacter sp. MCTG268].	24.83	596	378	20	72	633	86	645	7e-21	108
rs:WP_022297042	DNA topoisomerase [Clostridium sp. CAG:465].	24.36	669	396	25	2	629	17	616	7e-21	107
rs:WP_015863435	DNA topoisomerase I [Geobacillus sp. WCH70].	24.69	563	361	23	105	635	82	613	7e-21	107
rs:WP_027108419	DNA topoisomerase I [Lacticigenium naphtae].	23.77	669	400	24	3	629	6	606	7e-21	107
rs:WP_038684634	hypothetical protein, partial [Rubrobacter radiotolerans].	24.84	616	383	24	1	583	1	569	7e-21	107
rs:WP_004736442	topoisomerase I [Vibrio splendidus].	23.87	599	374	18	74	633	84	639	7e-21	108
rs:WP_038439864	DNA topoisomerase I [Haemophilus influenzae].	25.26	475	297	14	187	633	196	640	7e-21	108
rs:WP_021900264	DNA topoisomerase type IA central domain protein [Eggerthella sp. CAG:1427].	24.91	582	350	25	90	631	135	669	7e-21	108
rs:WP_019304179	DNA topoisomerase I [Xanthomonas oryzae].	24.61	573	344	20	3	538	5	526	7e-21	108
rs:XP_001851071	DNA topoisomerase 3-beta [Culex quinquefasciatus].	22.37	666	451	18	3	631	5	641	7e-21	108
tr:A0A0B8PFG7_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.33	300	189	10	89	362	32	331	7e-21	104
rs:WP_024745936	DNA topoisomerase I [Xanthomonas oryzae].	24.61	573	344	20	3	538	5	526	7e-21	108
rs:WP_040105642	DNA topoisomerase I [Salinicoccus roseus].	24.11	564	357	21	100	629	77	603	7e-21	107
rs:WP_031903339	DNA topoisomerase I [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	7e-21	107
tr:R4BEW2_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOM38169.1};	23.91	389	270	9	308	680	3	381	7e-21	105
rs:WP_017104280	topoisomerase I [Vibrio tasmaniensis].	23.87	599	374	18	74	633	84	639	7e-21	108
rs:WP_026965596	DNA topoisomerase I [Alicyclobacillus pomorum].	23.59	568	352	21	88	614	62	588	7e-21	107
rs:WP_039086764	DNA topoisomerase I [Gallibacterium anatis].	23.86	591	383	17	74	633	86	640	7e-21	108
tr:S3JEW5_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	35.21	213	120	8	190	385	1	212	7e-21	102
rs:WP_039431940	DNA topoisomerase I [Xanthomonas vasicola].	25.19	524	326	17	55	538	29	526	7e-21	108
rs:WP_031867779	DNA topoisomerase 1 [Staphylococcus aureus].	24.65	568	369	17	90	629	67	603	7e-21	107
sp:TOP1_BUCAI	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.56	566	361	16	74	614	79	603	7e-21	108
tr:A0A077V3Z6_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.30	568	371	17	90	629	69	605	7e-21	107
rs:WP_014509854	DNA topoisomerase I [Thermus thermophilus].	24.25	668	367	25	3	616	18	600	7e-21	107
tr:H1HCE5_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.97	620	366	23	2	589	9	567	7e-21	107
rs:WP_009500471	topoisomerase I [Haemophilus sp. oral taxon 851].	24.95	473	301	13	187	633	196	640	7e-21	108
tr:Q8RQG8_BACCE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:BAB88976.1}; Flags: Fragment;	38.79	165	93	5	61	222	12	171	7e-21	101
rs:WP_010890220	hypothetical protein [Streptococcus agalactiae].	36.17	188	102	6	3	179	4	184	7e-21	102
rs:WP_045645036	DNA topoisomerase I, partial [Peptococcaceae bacterium BRH_c4b].	23.92	556	361	16	90	616	67	589	7e-21	107
rs:WP_012534462	DNA topoisomerase [Aliivibrio fischeri].	23.68	684	405	27	3	600	2	654	7e-21	107
rs:XP_011332583	PREDICTED: DNA topoisomerase 3-beta-1 [Cerapachys biroi].	22.27	678	440	21	3	630	5	645	7e-21	108
rs:WP_014504887	DNA topoisomerase I [Xanthomonas oryzae].	24.61	573	344	20	3	538	5	526	8e-21	107
rs:WP_017095683	topoisomerase I [Vibrio splendidus].	23.87	599	374	18	74	633	84	639	8e-21	108
rs:WP_031786944	DNA topoisomerase I [Staphylococcus aureus].	24.30	568	371	17	90	629	67	603	8e-21	107
rs:WP_006036574	DNA topoisomerase I [Paenibacillus curdlanolyticus].	24.16	596	364	26	88	636	62	616	8e-21	107
rs:WP_044810431	DNA topoisomerase I [Bacillus cereus].	24.47	564	361	21	105	635	82	613	8e-21	107
rs:WP_039135930	DNA topoisomerase I [Gallibacterium genomosp. 2].	23.86	591	383	17	74	633	86	640	8e-21	108
rs:WP_000520423	topoisomerase I [Vibrio albensis].	24.30	605	362	22	75	633	87	641	8e-21	108
tr:G8N977_9DEIN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.70	591	337	24	77	616	49	582	8e-21	107
rs:WP_017174596	MULTISPECIES: DNA topoisomerase I [Staphylococcus].	25.95	555	352	21	103	629	80	603	8e-21	107
rs:WP_003442199	DNA topoisomerase I [Clostridium pasteurianum].	25.27	641	395	19	3	616	5	588	8e-21	107
rs:WP_046720325	DNA topoisomerase III, partial [Pseudomonas syringae].	29.08	251	160	7	1	242	1	242	8e-21	103
rs:WP_024711277	DNA topoisomerase I [Xanthomonas oryzae].	24.61	573	344	20	3	538	5	526	8e-21	107
rs:WP_019225611	MULTISPECIES: DNA topoisomerase I [Dehalobacter].	24.22	702	435	28	3	671	5	642	8e-21	107
rs:WP_006746967	DNA topoisomerase I [Thioalkalivibrio thiocyanoxidans].	24.52	522	323	18	55	534	29	521	8e-21	107
rs:WP_006654231	DNA topoisomerase I [Natrialba hulunbeirensis].	21.88	736	448	27	1	661	1	684	8e-21	107
rs:WP_004812098	DNA topoisomerase I [Anaerococcus hydrogenalis].	25.55	677	374	29	3	630	5	600	8e-21	107
rs:WP_012032416	DNA topoisomerase I [Pelotomaculum thermopropionicum].	24.16	567	356	18	88	616	62	592	8e-21	107
rs:WP_039171518	DNA topoisomerase I [Gallibacterium genomosp. 1].	23.82	592	382	18	74	633	86	640	8e-21	107
rs:WP_033861012	DNA topoisomerase 1 [Staphylococcus aureus].	24.47	568	370	17	90	629	67	603	8e-21	107
sp:TOP1_STAHJ	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.35	572	360	20	90	629	67	603	8e-21	107
tr:C0GIT5_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.08	579	351	22	90	630	67	606	8e-21	107
rs:WP_040204980	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.46	560	367	20	105	635	82	614	8e-21	107
rs:WP_014630190	DNA topoisomerase I [Thermus thermophilus].	24.25	668	367	25	3	616	18	600	8e-21	107
rs:WP_036141355	DNA topoisomerase I [Lysinibacillus sp. BF-4].	24.14	580	381	18	105	654	82	632	8e-21	107
rs:WP_021795786	hypothetical protein [Thermoplasmatales archaeon A-plasma].	25.66	647	405	24	3	616	9	612	8e-21	107
rs:WP_004215386	DNA topoisomerase I [Natrialba magadii].	21.88	736	448	27	1	661	1	684	8e-21	107
rs:WP_047340222	DNA topoisomerase I [Xanthomonas oryzae].	24.61	573	344	20	3	538	5	526	8e-21	107
rs:WP_031892887	DNA topoisomerase III, partial [Staphylococcus aureus].	37.64	178	98	5	3	175	4	173	8e-21	101
rs:WP_019300052	DNA topoisomerase I [Xanthomonas oryzae].	24.61	573	344	20	3	538	5	526	8e-21	107
rs:WP_029764261	DNA topoisomerase I [Gemmatimonadetes bacterium JGI 0000112-M07].	23.27	649	395	24	3	614	5	587	8e-21	107
rs:WP_019234829	DNA topoisomerase I [Legionella anisa].	24.67	677	399	28	3	630	5	619	8e-21	107
rs:WP_023614906	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.55	554	361	19	105	630	82	606	8e-21	107
rs:WP_038541104	DNA topoisomerase I [Bacillus sp. X1(2014)].	24.96	569	355	24	105	636	82	615	8e-21	107
rs:WP_028273113	DNA topoisomerase I [Atopococcus tabaci].	23.68	663	409	21	3	629	6	607	8e-21	107
tr:Q7P6B1_FUSNV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.16	616	376	19	2	589	12	570	9e-21	107
rs:WP_000179677	DNA topoisomerase I [Streptococcus sp. SK140].	24.53	579	364	22	83	629	71	608	9e-21	107
rs:WP_000520428	topoisomerase I [Vibrio cholerae].	24.30	605	362	22	75	633	87	641	9e-21	107
rs:WP_010139696	DNA topoisomerase I [Oceanicola sp. S124].	22.68	679	417	24	1	629	1	621	9e-21	107
rs:WP_022433392	DNA topoisomerase [Eubacterium sp. CAG:38].	24.89	458	286	14	187	616	17	444	9e-21	106
rs:WP_039472168	DNA topoisomerase I [Pedobacter kyungheensis].	25.97	516	330	15	77	578	54	531	9e-21	107
rs:WP_044525682	DNA topoisomerase I [Francisella philomiragia].	25.00	624	398	22	74	656	51	645	9e-21	107
rs:WP_024727734	DNA topoisomerase I [Clostridiales bacterium VE202-09].	23.56	658	385	24	3	616	5	588	9e-21	107
rs:WP_008297203	DNA topoisomerase 1 [Bhargavaea cecembensis].	24.69	567	365	20	100	635	78	613	9e-21	107
rs:WP_016532565	DNA topoisomerase III, partial [Klebsiella pneumoniae].	34.44	180	110	4	405	581	22	196	9e-21	102
rs:WP_008724189	DNA topoisomerase I [Brachyspira hampsonii].	23.70	671	398	23	3	629	28	628	9e-21	107
rs:WP_008691655	DNA topoisomerase I [Fusobacterium nucleatum].	25.85	619	368	22	2	589	12	570	9e-21	107
rs:WP_011117558	DNA topoisomerase I [Campylobacter jejuni].	25.33	529	335	16	81	579	55	553	9e-21	107
tr:R4E063_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOM38168.1};	37.14	210	125	3	103	305	3	212	9e-21	102
rs:WP_039091086	DNA topoisomerase I [Gallibacterium anatis].	23.77	589	382	17	74	631	86	638	9e-21	107
tr:A0A078MI83_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.14	580	381	18	105	654	82	632	9e-21	107
rs:WP_023920771	DNA topoisomerase I [Rhodobacter capsulatus].	22.73	682	423	20	1	638	1	622	9e-21	107
rs:XP_011252740	PREDICTED: DNA topoisomerase 3-beta-1 [Camponotus floridanus].	22.19	676	443	21	3	630	5	645	9e-21	107
rs:WP_022204968	DNA topoisomerase [Eubacterium sp. CAG:248].	25.44	570	348	21	83	616	60	588	9e-21	107
rs:WP_025113925	DNA topoisomerase I [Lysinibacillus fusiformis].	24.10	556	364	16	103	629	80	606	9e-21	107
tr:A3IRZ5_9CHRO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.73	614	351	23	85	641	91	656	9e-21	107
rs:WP_038371482	DNA topoisomerase I [Fusobacterium nucleatum].	25.16	616	376	19	2	589	9	567	9e-21	107
rs:WP_009846346	topoisomerase I [Vibrio sp. MED222].	23.87	599	374	18	74	633	84	639	9e-21	107
rs:WP_013068797	DNA topoisomerase I [Rhodobacter capsulatus].	22.73	682	423	20	1	638	1	622	9e-21	107
rs:WP_041433679	DNA topoisomerase I [Thermus sp. CCB_US3_UF1].	24.70	591	337	24	77	616	50	583	9e-21	107
rs:WP_029098937	DNA topoisomerase I [Brevibacillus thermoruber].	24.11	564	369	22	103	636	80	614	9e-21	107
rs:WP_031587734	DNA topoisomerase I [Lachnospiraceae bacterium P6A3].	23.32	626	391	22	90	675	67	643	9e-21	107
rs:WP_017144898	DNA topoisomerase I [Fusobacterium nucleatum].	25.97	620	366	23	2	589	12	570	9e-21	107
rs:WP_002503404	DNA topoisomerase I [Staphylococcus epidermidis].	24.33	559	362	18	100	629	77	603	1e-20	107
rs:WP_014038639	DNA topoisomerase I [Stenotrophomonas maltophilia].	24.57	578	338	20	3	538	5	526	1e-20	107
rs:WP_000179637	DNA topoisomerase I [Streptococcus pneumoniae].	23.70	578	370	18	83	629	71	608	1e-20	107
rs:WP_029565595	DNA topoisomerase I [Bacillus cibi].	23.98	563	365	19	105	635	82	613	1e-20	107
rs:WP_021961263	DNA topoisomerase [Butyrivibrio crossotus CAG:259].	25.24	634	361	25	90	671	67	639	1e-20	107
rs:WP_028383191	DNA topoisomerase I [Legionella moravica].	25.16	628	381	25	55	630	29	619	1e-20	107
rs:WP_005419627	DNA topoisomerase I [Stenotrophomonas maltophilia].	25.17	580	332	21	3	538	5	526	1e-20	107
rs:WP_007104511	DNA topoisomerase I [Glaciecola polaris].	24.35	620	358	23	65	629	75	638	1e-20	107
rs:WP_039031854	DNA topoisomerase I [Leclercia adecarboxylata].	25.17	596	373	23	73	633	76	633	1e-20	107
rs:WP_021945740	DNA topoisomerase [Clostridium sp. CAG:967].	23.86	700	402	26	3	646	14	638	1e-20	107
rs:WP_021787017	hypothetical protein, partial [Ferroplasma sp. Type II].	26.54	648	392	28	3	618	1	596	1e-20	107
rs:WP_037584519	DNA topoisomerase I [Streptococcus intermedius].	23.69	574	377	19	83	630	71	609	1e-20	107
rs:WP_039166606	DNA topoisomerase I [Gallibacterium anatis].	23.86	591	383	17	74	633	86	640	1e-20	107
rs:WP_038088810	DNA topoisomerase I [Tumebacillus flagellatus].	23.61	538	355	15	103	614	81	588	1e-20	107
rs:WP_029281361	DNA topoisomerase I [Bacillus indicus].	23.98	563	365	19	105	635	82	613	1e-20	107
rs:WP_013143479	DNA topoisomerase I [Staphylothermus hellenicus].	24.86	551	357	20	90	615	142	660	1e-20	107
rs:WP_023918843	DNA topoisomerase I [Rhodobacter capsulatus].	22.73	682	423	20	1	638	1	622	1e-20	107
rs:WP_001897682	topoisomerase I [Vibrio cholerae].	24.30	605	362	22	75	633	87	641	1e-20	107
rs:WP_012619491	topoisomerase I [Buchnera aphidicola].	24.73	566	360	16	74	614	79	603	1e-20	107
tr:V1CS44_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.81	669	400	28	3	635	34	635	1e-20	107
rs:WP_037558001	DNA topoisomerase I [Staphylococcus haemolyticus].	25.35	572	360	20	90	629	67	603	1e-20	107
rs:WP_022306116	DNA topoisomerase [Roseburia sp. CAG:380].	24.60	626	383	19	90	675	67	643	1e-20	107
rs:WP_020795116	hypothetical protein [Pseudomonas sp. G5(2012)].	24.44	626	390	23	55	631	28	619	1e-20	107
rs:WP_013253491	DNA topoisomerase I [Spirochaeta smaragdinae].	24.91	578	334	20	3	530	6	533	1e-20	107
rs:WP_044657087	DNA topoisomerase I, partial [Bacteroides acidifaciens].	26.62	308	214	7	373	677	6	304	1e-20	103
rs:WP_028986563	DNA topoisomerase I [Thermicanus aegyptius].	24.87	567	359	23	103	635	80	613	1e-20	107
tr:R2QYG4_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.98	278	182	5	276	541	4	272	1e-20	103
rs:WP_023495199	DNA topoisomerase 1 [Methyloglobulus morosus].	23.59	674	411	28	3	630	5	620	1e-20	107
rs:WP_041074035	DNA topoisomerase I [Bacillus sp. OxB-1].	24.33	563	360	18	100	629	77	606	1e-20	107
rs:WP_011174282	DNA topoisomerase I [Thermus thermophilus].	24.25	668	367	25	3	616	18	600	1e-20	107
rs:WP_035290647	DNA topoisomerase I [Clostridium sp. KNHs214].	27.43	565	327	22	90	616	67	586	1e-20	107
rs:WP_000520429	topoisomerase I [Vibrio cholerae].	24.30	605	362	22	75	633	87	641	1e-20	107
rs:WP_002502089	DNA topoisomerase I [Staphylococcus epidermidis].	24.33	559	362	18	100	629	77	603	1e-20	107
rs:WP_010431771	topoisomerase I [Enterobacter mori].	24.19	587	382	20	76	633	82	634	1e-20	107
rs:WP_010936459	DNA topoisomerase I [Dehalococcoides mccartyi].	25.07	674	387	26	2	624	4	610	1e-20	107
rs:WP_021073552	DNA topoisomerase I [haloarchaeon 3A1_DGR].	22.94	741	449	31	2	661	6	705	1e-20	107
rs:WP_044683261	DNA topoisomerase I [Streptococcus suis].	23.66	579	370	19	83	629	72	610	1e-20	107
rs:WP_005913038	DNA topoisomerase I [Fusobacterium nucleatum].	25.12	617	375	20	2	589	9	567	1e-20	107
rs:WP_033919532	DNA topoisomerase I [Sphingomonas sp. 37zxx].	22.90	668	422	22	1	629	1	614	1e-20	107
rs:WP_023252897	DNA topoisomerase III, partial [Salmonella enterica].	35.33	167	102	3	418	581	25	188	1e-20	102
rs:WP_006597227	DNA topoisomerase I [Streptococcus australis].	23.36	578	372	18	83	629	53	590	1e-20	107
rs:WP_019829856	topoisomerase I [Vibrio cholerae].	24.30	605	362	22	75	633	87	641	1e-20	107
rs:WP_021978486	DNA topoisomerase [Clostridium sp. CAG:793].	25.68	588	357	25	83	629	60	608	1e-20	107
rs:WP_014421722	topoisomerase I [Marinobacter hydrocarbonoclasticus].	23.91	594	374	16	76	633	93	644	1e-20	107
rs:WP_000179623	DNA topoisomerase I [Streptococcus sp. C300].	23.97	580	366	22	83	629	71	608	1e-20	107
rs:WP_024394027	DNA topoisomerase I [Streptococcus suis].	23.40	577	374	18	83	629	72	610	1e-20	107
tr:A0A077VUX2_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.18	568	366	19	90	629	69	605	1e-20	107
rs:WP_015702243	topoisomerase I [Haemophilus influenzae].	25.58	477	293	13	187	633	196	640	1e-20	107
rs:WP_046121520	DNA topoisomerase I [Vibrio cholerae].	24.30	605	362	22	75	633	87	641	1e-20	107
rs:WP_024938530	DNA topoisomerase I [Xanthomonas arboricola].	24.61	573	344	20	3	538	5	526	1e-20	107
rs:WP_012775128	DNA topoisomerase I [Streptococcus suis].	23.66	579	370	19	83	629	72	610	1e-20	107
rs:WP_040153697	DNA topoisomerase III, partial [Klebsiella pneumoniae].	31.60	231	134	7	1	219	1	219	1e-20	102
rs:XP_008792955	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Phoenix dactylifera].	22.66	578	380	19	37	586	7	545	1e-20	107
rs:WP_002446285	DNA topoisomerase I [Staphylococcus epidermidis].	24.33	559	362	18	100	629	77	603	1e-20	107
rs:WP_032891759	DNA topoisomerase I [Fusobacterium nucleatum].	25.28	617	374	21	2	589	12	570	1e-20	107
rs:WP_000520440	topoisomerase I [Vibrio mimicus].	24.14	613	373	21	57	633	85	641	1e-20	107
rs:WP_044764051	DNA topoisomerase I [Streptococcus suis].	23.66	579	370	19	83	629	72	610	1e-20	107
rs:WP_018379577	DNA topoisomerase I [Streptococcus thoraltensis].	23.79	580	368	20	83	629	84	622	1e-20	107
rs:WP_002476657	DNA topoisomerase I [Staphylococcus epidermidis].	24.33	559	362	18	100	629	77	603	1e-20	107
tr:R8ULT3_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.80	216	132	7	112	321	1	211	1e-20	102
rs:WP_005357832	DNA topoisomerase I [[Eubacterium] siraeum].	25.56	630	383	24	82	671	72	655	1e-20	107
rs:WP_000520430	topoisomerase I [Vibrio cholerae].	24.30	605	362	22	75	633	87	641	1e-20	107
rs:WP_000520439	topoisomerase I [Vibrio mimicus].	24.14	613	373	21	57	633	85	641	1e-20	107
rs:WP_039446947	DNA topoisomerase I [Xanthomonas vasicola].	24.61	573	344	20	3	538	5	526	1e-20	107
tr:U7TQJ4_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.28	617	374	21	2	589	9	567	1e-20	107
rs:WP_017062103	topoisomerase I [Vibrio crassostreae].	23.71	603	370	19	74	633	84	639	1e-20	107
rs:WP_003712732	toprim domain protein, partial [Lactobacillus oris].	34.12	211	129	6	3	204	4	213	1e-20	102
rs:WP_046344689	DNA topoisomerase I [Xanthomonas campestris].	24.61	573	344	20	3	538	5	526	1e-20	107
rs:WP_032844749	DNA topoisomerase I, partial [Fusobacterium nucleatum].	25.12	617	375	20	2	589	9	567	1e-20	107
rs:WP_035799481	DNA topoisomerase I [Cyanothece sp. CCY0110].	25.81	616	348	24	85	641	71	636	1e-20	107
rs:WP_036181603	DNA topoisomerase I [Lysinibacillus manganicus].	25.85	557	349	22	105	629	82	606	1e-20	107
rs:WP_047127472	DNA topoisomerase I [Xanthomonas arboricola].	24.61	573	344	20	3	538	5	526	1e-20	107
tr:K0FR22_BACTU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.93	560	369	20	105	635	52	583	1e-20	107
rs:WP_013010160	DNA topoisomerase I [Denitrovibrio acetiphilus].	24.33	670	393	25	3	629	5	603	1e-20	107
rs:WP_022685102	DNA topoisomerase I [Sphingomonas phyllosphaerae].	21.96	674	421	22	1	629	1	614	1e-20	107
tr:A0A073BTT1_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KEI54916.1};	39.39	165	89	5	49	204	1	163	1e-20	100
rs:WP_039936927	DNA topoisomerase I [Leptospira terpstrae].	23.44	657	403	18	36	630	6	624	1e-20	106
rs:WP_040228112	DNA topoisomerase I [Bhargavaea cecembensis].	24.82	564	362	20	103	635	80	612	1e-20	107
rs:WP_016646347	hypothetical protein [Campylobacter ureolyticus].	26.61	511	312	18	100	578	72	551	1e-20	106
tr:X8HDT0_9FUSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.60	695	433	22	2	671	9	637	1e-20	107
rs:WP_017067846	topoisomerase I [Vibrio crassostreae].	23.68	604	369	19	74	633	84	639	1e-20	107
rs:WP_023792924	hypothetical protein [candidate division SR1 bacterium RAAC1_SR1_1].	23.47	605	388	19	3	595	5	546	1e-20	107
rs:WP_042594644	DNA topoisomerase I [Haemophilus influenzae].	25.05	475	298	14	187	633	196	640	1e-20	107
rs:WP_009140840	DNA topoisomerase [Collinsella tanakaei].	21.85	563	369	20	87	620	133	653	1e-20	107
rs:WP_006907650	DNA topoisomerase I [Facklamia hominis].	24.52	575	357	21	90	629	68	600	1e-20	107
rs:WP_039524995	DNA topoisomerase I [Xanthomonas arboricola].	24.61	573	344	20	3	538	5	526	1e-20	107
rs:WP_021841057	DNA topoisomerase [Veillonella sp. CAG:933].	23.21	573	361	20	95	629	129	660	1e-20	107
rs:WP_022790860	DNA topoisomerase I [Weissella halotolerans].	24.40	668	397	25	3	630	27	626	1e-20	107
rs:WP_011272639	topoisomerase I [Haemophilus influenzae].	25.05	475	298	14	187	633	196	640	1e-20	107
rs:WP_001286962	DNA topoisomerase I [Bacillus cereus].	23.88	582	384	21	105	655	82	635	1e-20	107
rs:WP_032846708	DNA topoisomerase I [Fusobacterium sp. CM22].	24.60	695	433	22	2	671	12	640	1e-20	107
rs:WP_017115144	DNA topoisomerase I [Xanthomonas vasicola].	24.61	573	344	20	3	538	5	526	1e-20	107
rs:WP_036622237	DNA topoisomerase I [Paenibacillus macerans].	24.10	585	378	22	88	636	62	616	1e-20	107
tr:A0A099Q3J4_9XANT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.61	573	344	20	3	538	5	526	1e-20	107
rs:WP_022578139	topoisomerase I [Vibrio mimicus].	24.14	613	373	21	57	633	85	641	1e-20	107
rs:WP_027831857	DNA topoisomerase I [Marinobacter sp. HL-58].	24.45	589	378	18	76	633	93	645	1e-20	107
rs:WP_003712163	toprim domain protein, partial [Lactobacillus oris].	35.07	211	127	7	3	204	4	213	1e-20	101
rs:WP_005656771	topoisomerase I [Haemophilus influenzae].	25.05	475	298	14	187	633	196	640	1e-20	107
rs:WP_032823520	DNA topoisomerase I [Haemophilus influenzae].	25.05	475	298	14	187	633	196	640	1e-20	107
rs:WP_043983542	DNA topoisomerase I [Streptococcus equi].	24.18	579	369	21	83	630	84	623	1e-20	107
rs:WP_034637643	DNA topoisomerase I [Desulfovibrio cuneatus].	23.77	589	354	18	79	615	54	599	1e-20	106
rs:WP_019349908	DNA topoisomerase I [Fluoribacter dumoffii].	26.07	633	369	30	55	630	29	619	1e-20	107
rs:WP_047103157	DNA topoisomerase I [Brachyspira hyodysenteriae].	23.61	665	406	23	3	629	28	628	1e-20	107
rs:WP_046510821	DNA topoisomerase I [Salinicoccus sp. SV-16].	23.38	556	365	19	103	629	80	603	1e-20	106
rs:WP_032888841	DNA topoisomerase I [Fusobacterium nucleatum].	25.28	617	374	21	2	589	12	570	1e-20	107
rs:WP_046964308	DNA topoisomerase I [Xanthomonas pisi].	24.61	573	344	20	3	538	5	526	1e-20	107
rs:WP_018369651	DNA topoisomerase I [Streptococcus marimammalium].	24.01	583	363	21	83	629	73	611	1e-20	106
rs:WP_042987746	DNA topoisomerase I [Vibrio cholerae].	24.30	605	362	22	75	633	87	641	1e-20	107
rs:WP_006773684	DNA topoisomerase III [[Clostridium] hathewayi].	43.09	123	54	4	3	118	11	124	1e-20	99.8
tr:C2UZ72_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.93	560	369	20	105	635	52	583	1e-20	106
rs:WP_018292829	DNA topoisomerase I [Gallionella sp. SCGC AAA018-N21].	24.19	682	388	28	3	629	5	612	1e-20	107
rs:WP_044126648	DNA topoisomerase I [Vibrio cholerae].	24.30	605	362	22	75	633	87	641	1e-20	107
rs:WP_042144852	DNA topoisomerase I [Paucisalibacillus sp. EB02].	25.57	567	356	22	103	635	80	614	1e-20	106
rs:WP_036123967	MULTISPECIES: DNA topoisomerase I [Lysinibacillus].	23.92	556	365	16	103	629	80	606	1e-20	106
rs:WP_015359063	DNA topoisomerase 1 [[Clostridium] stercorarium].	24.28	622	387	25	90	671	67	644	1e-20	107
rs:WP_020064141	DNA topoisomerase I [Brachyspira hyodysenteriae].	23.61	665	406	23	3	629	28	628	1e-20	107
rs:WP_039154270	DNA topoisomerase I [Gallibacterium anatis].	23.65	592	383	18	74	633	86	640	1e-20	107
rs:WP_010858431	DNA topoisomerase I [Lysinibacillus sphaericus].	23.70	557	367	15	103	630	80	607	1e-20	106
tr:X7RZ04_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.28	617	374	21	2	589	9	567	1e-20	107
rs:WP_033929724	DNA topoisomerase I [Vibrio cholerae].	24.30	605	362	22	75	633	87	641	1e-20	107
tr:A4NYH0_HAEIF	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.05	475	298	14	187	633	196	640	1e-20	107
rs:WP_036868463	DNA topoisomerase I, partial [Prevotella bivia].	34.95	186	103	5	4	178	5	183	1e-20	101
rs:WP_003076379	DNA topoisomerase I [Streptococcus intermedius].	23.52	574	378	19	83	630	70	608	1e-20	106
rs:WP_040803059	DNA topoisomerase I [Streptococcus australis].	23.36	578	372	18	83	629	71	608	1e-20	106
rs:WP_031548586	DNA topoisomerase I [Salinicoccus luteus].	24.11	564	357	21	100	629	77	603	1e-20	106
rs:WP_010376861	DNA topoisomerase I [Xanthomonas campestris].	24.61	573	344	20	3	538	5	526	1e-20	107
rs:WP_010714635	hypothetical protein, partial [Enterococcus faecalis].	36.96	184	106	6	3	179	4	184	1e-20	101
gp:AP010969_875	DNA topoisomerase I [Streptococcus intermedius JTH08]	23.52	574	378	19	83	630	73	611	1e-20	106
rs:WP_022484853	DNA topoisomerase [Fusobacterium sp. CAG:815].	24.96	689	394	26	3	636	12	632	1e-20	107
rs:WP_031524090	DNA topoisomerase I, partial [Cronobacter sp. 1383].	24.00	600	378	17	73	633	74	634	1e-20	106
rs:WP_039139011	DNA topoisomerase I [Gallibacterium anatis].	23.69	591	384	17	74	633	86	640	1e-20	107
tr:E7SBC1_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.36	578	372	18	83	629	81	618	2e-20	106
rs:WP_016080527	MULTISPECIES: DNA topoisomerase 1 [Bacillus].	23.88	582	384	21	105	655	82	635	2e-20	106
rs:WP_002496234	DNA topoisomerase I [Staphylococcus epidermidis].	24.33	559	362	18	100	629	77	603	2e-20	106
tr:E4Y9R3_OIKDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.01	604	376	21	3	564	5	567	2e-20	107
rs:WP_044474989	DNA topoisomerase III, partial [Xanthomonas campestris].	30.04	223	141	6	1	216	1	215	2e-20	101
rs:WP_000520437	topoisomerase I [Vibrio mimicus].	24.15	621	363	23	57	633	85	641	2e-20	107
rs:WP_016837424	DNA topoisomerase I [Ureibacillus thermosphaericus].	23.60	555	366	18	105	630	82	607	2e-20	106
rs:WP_010259203	DNA topoisomerase I [Treponema primitia].	23.80	584	362	20	89	630	73	615	2e-20	106
rs:WP_028967690	DNA topoisomerase I [Sphingomonas phyllosphaerae].	22.67	666	426	23	1	629	1	614	2e-20	107
rs:WP_015707647	DNA topoisomerase I [Treponema primitia].	24.69	567	357	19	97	629	99	629	2e-20	106
rs:WP_023260375	DNA topoisomerase III, partial [Salmonella enterica].	32.31	195	125	4	418	608	28	219	2e-20	102
rs:WP_004839147	DNA topoisomerase I [Anaerococcus vaginalis].	25.37	670	384	27	3	630	5	600	2e-20	106
rs:WP_010236162	DNA topoisomerase I [Clostridium arbusti].	26.07	560	357	18	83	616	60	588	2e-20	106
rs:WP_041333211	DNA topoisomerase I [Marinobacter salarius].	24.83	596	378	20	72	633	86	645	2e-20	107
rs:WP_039413639	DNA topoisomerase I [Xanthomonas campestris].	24.61	573	344	20	3	538	5	526	2e-20	107
rs:WP_001286959	DNA topoisomerase I [Bacillus thuringiensis].	23.93	560	369	20	105	635	82	613	2e-20	106
rs:WP_039564478	DNA topoisomerase I, partial [Xanthomonas campestris].	24.61	573	344	20	3	538	5	526	2e-20	106
rs:WP_000520433	topoisomerase I [Vibrio cholerae].	24.30	605	362	22	75	633	87	641	2e-20	107
rs:WP_000520424	topoisomerase I [Vibrio cholerae].	24.30	605	362	22	75	633	87	641	2e-20	107
sp:TOP1_VIBCH	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.30	605	362	22	75	633	87	641	2e-20	107
rs:WP_005666969	topoisomerase I [Haemophilus influenzae].	25.05	475	298	14	187	633	196	640	2e-20	107
rs:WP_018661545	DNA topoisomerase I [Thermobrachium celere].	24.10	581	370	17	83	629	60	603	2e-20	106
rs:WP_022740226	DNA topoisomerase [Adlercreutzia equolifaciens].	24.01	579	333	20	90	616	135	658	2e-20	107
rs:WP_001286961	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	23.93	560	369	20	105	635	82	613	2e-20	106
rs:WP_010652788	DNA topoisomerase I [Fluoribacter dumoffii].	26.07	633	369	30	55	630	29	619	2e-20	106
rs:WP_010093441	DNA topoisomerase I [Ornithinibacillus scapharcae].	25.13	581	367	23	90	635	67	614	2e-20	106
rs:WP_009228558	DNA topoisomerase I [Prevotella sp. oral taxon 299].	25.21	595	361	19	3	578	5	534	2e-20	106
tr:A0A077VAY5_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.30	568	371	17	90	629	69	605	2e-20	106
rs:WP_009571103	DNA topoisomerase I [Celeribacter baekdonensis].	22.82	701	408	27	1	629	1	640	2e-20	107
rs:WP_002457370	DNA topoisomerase I [Staphylococcus epidermidis].	24.51	559	361	19	100	629	77	603	2e-20	106
rs:WP_013841888	DNA topoisomerase I [Desulfotomaculum ruminis].	24.28	556	366	15	88	616	62	589	2e-20	106
rs:WP_033928613	DNA topoisomerase I [Vibrio cholerae].	24.30	605	362	22	75	633	87	641	2e-20	107
rs:WP_024405688	DNA topoisomerase I [Streptococcus suis].	23.40	577	374	18	83	629	72	610	2e-20	106
tr:A0A090WAW1_9FLAO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL72564.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL72564.1};	30.18	275	169	11	420	676	24	293	2e-20	103
rs:WP_021951438	DNA topoisomerase [Clostridium sp. CAG:678].	24.38	566	356	18	88	616	61	591	2e-20	106
rs:WP_022183068	DNA topoisomerase [Clostridium sp. CAG:575].	24.64	560	355	20	103	629	80	605	2e-20	106
sp:TOP1_STAEQ	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.33	559	362	18	100	629	77	603	2e-20	106
rs:WP_011448040	DNA topoisomerase I [Methanospirillum hungatei].	22.75	677	422	27	1	633	1	620	2e-20	107
tr:A0A068UPW2_COFCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.51	672	430	28	3	631	6	636	2e-20	106
rs:WP_045281238	DNA topoisomerase I [Enterobacter sp. 44593].	24.27	585	384	18	76	633	82	634	2e-20	107
tr:A0A062V8Y9_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.55	660	422	27	1	630	1	614	2e-20	106
rs:WP_035735116	DNA topoisomerase I [Francisella philomiragia].	25.29	597	377	21	74	629	51	619	2e-20	106
tr:C9AKL3_ENTFC	SubName: Full=Type 1 topoisomerase {ECO:0000313|EMBL:EEV60553.1};	39.39	165	89	5	49	204	1	163	2e-20	100
tr:U2J849_PORGN	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERJ82416.1}; Flags: Fragment;	31.14	228	146	6	172	393	1	223	2e-20	101
rs:WP_045515241	DNA topoisomerase I [Bacillus niacini].	25.22	559	352	21	105	630	82	607	2e-20	106
rs:WP_040969433	DNA topoisomerase I [Mesorhizobium sp. ORS3324].	23.30	704	395	26	1	630	1	633	2e-20	107
rs:WP_019660785	DNA topoisomerase I [Stenotrophomonas maltophilia].	24.57	578	338	20	3	538	5	526	2e-20	106
rs:WP_011640264	DNA topoisomerase I [Syntrophomonas wolfei].	24.24	623	389	21	90	675	68	644	2e-20	106
rs:WP_020156269	DNA topoisomerase I [Caldibacillus debilis].	24.65	564	360	19	105	635	82	613	2e-20	106
rs:WP_045846408	DNA topoisomerase I [Aquitalea magnusonii].	24.18	579	380	16	84	630	61	612	2e-20	106
rs:WP_042516839	DNA topoisomerase I [Francisella philomiragia].	25.29	597	377	21	74	629	51	619	2e-20	106
rs:XP_004039715	hypothetical protein IMG5_012580, partial [Ichthyophthirius multifiliis].	25.23	650	369	28	3	587	57	654	2e-20	106
rs:WP_022068892	DNA topoisomerase [Blautia sp. CAG:257].	23.38	556	362	19	90	616	67	587	2e-20	106
rs:WP_039518565	DNA topoisomerase I [Xanthomonas arboricola].	24.61	573	344	20	3	538	5	526	2e-20	106
rs:WP_046439302	DNA topoisomerase I [Ruminococcus sp. N15.MGS-57].	23.83	579	382	16	82	629	58	608	2e-20	106
rs:WP_021203233	DNA topoisomerase I [Stenotrophomonas maltophilia].	24.57	578	338	20	3	538	5	526	2e-20	106
rs:WP_000520435	topoisomerase I [Vibrio cholerae].	24.30	605	362	22	75	633	87	641	2e-20	106
rs:WP_005523284	DNA topoisomerase I [Vibrio mimicus].	24.14	613	373	21	57	633	85	641	2e-20	106
tr:N1W1T2_9LEPT	SubName: Full=Putative DNA topoisomerase I {ECO:0000313|EMBL:EMY63225.1};	24.09	606	369	16	87	630	21	597	2e-20	106
rs:WP_024305136	DNA topoisomerase I, partial [Cloacimonetes bacterium SCGC AAA252-P10].	27.44	583	346	23	83	629	55	596	2e-20	106
rs:WP_005331658	DNA topoisomerase I [Dorea formicigenerans].	23.87	620	388	22	90	671	67	640	2e-20	106
rs:WP_006996046	topoisomerase I [Haemophilus aegyptius].	25.26	475	297	14	187	633	196	640	2e-20	106
tr:E9FHA4_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.97	580	366	22	83	629	77	614	2e-20	106
rs:WP_047101136	DNA topoisomerase I [Brachyspira hyodysenteriae].	23.61	665	406	23	3	629	28	628	2e-20	106
rs:WP_029376441	DNA topoisomerase 1 [Staphylococcus epidermidis].	24.33	559	362	18	100	629	77	603	2e-20	106
rs:WP_041848588	DNA topoisomerase I [Bacillus thermoamylovorans].	24.83	576	374	24	105	649	82	629	2e-20	106
rs:WP_008267195	DNA topoisomerase I [Stenotrophomonas sp. SKA14].	24.57	578	338	20	3	538	5	526	2e-20	106
rs:WP_047112909	DNA topoisomerase I [Brachyspira hyodysenteriae].	23.63	673	396	24	3	629	28	628	2e-20	106
rs:WP_036129296	DNA topoisomerase I [Marinobacter sp. AK21].	25.08	598	374	21	72	633	86	645	2e-20	106
rs:WP_022097363	DNA topoisomerase [Eubacterium eligens CAG:72].	24.26	577	332	20	90	616	67	588	2e-20	106
rs:WP_039150646	DNA topoisomerase I [Gallibacterium anatis].	23.69	591	384	17	74	633	86	640	2e-20	106
rs:WP_022286871	DNA topoisomerase [Ruminococcus sp. CAG:57].	23.83	579	382	16	82	629	58	608	2e-20	106
tr:M1ZQM3_CLOBO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKN41862.1}; Flags: Fragment;	33.89	180	110	5	68	243	1	175	2e-20	100
rs:WP_012672070	DNA topoisomerase I [Brachyspira hyodysenteriae].	23.63	673	396	24	3	629	28	628	2e-20	106
rs:WP_041177573	DNA topoisomerase I, partial [Brachyspira intermedia].	23.61	665	406	23	3	629	15	615	2e-20	106
rs:WP_013747230	topoisomerase I [Gallibacterium anatis].	23.65	592	383	18	74	633	86	640	2e-20	106
rs:WP_008471813	DNA topoisomerase I [Lactobacillus hominis].	24.38	566	358	20	103	635	85	613	2e-20	106
rs:WP_047104919	DNA topoisomerase I [Brachyspira hyodysenteriae].	23.63	673	396	24	3	629	28	628	2e-20	106
rs:WP_032984924	DNA topoisomerase I [Cronobacter condimenti].	24.47	609	364	23	73	633	74	634	2e-20	106
rs:WP_038065387	hypothetical protein, partial [Thermodesulfovibrio thiophilus].	25.75	598	346	22	89	629	62	618	2e-20	106
rs:WP_044898007	DNA topoisomerase I [Aeribacillus pallidus].	24.11	564	369	22	103	636	80	614	2e-20	106
rs:WP_020252236	MULTISPECIES: hypothetical protein [unclassified Cloacimonetes].	27.44	583	346	23	83	629	60	601	2e-20	106
rs:WP_032656725	DNA topoisomerase I [Enterobacter sp. DC1].	23.92	602	365	23	76	633	82	634	2e-20	106
rs:WP_034605787	DNA topoisomerase I [Desulfovibrio desulfuricans].	24.25	569	358	19	72	614	47	568	2e-20	105
rs:WP_010282476	DNA topoisomerase I [Bacillus timonensis].	24.16	563	364	22	105	635	82	613	2e-20	106
rs:WP_027439327	DNA topoisomerase I [Lachnospiraceae bacterium AC2031].	25.51	588	348	23	3	560	5	532	2e-20	106
rs:WP_038671950	DNA topoisomerase I [Ruminococcus bicirculans].	23.83	579	382	16	82	629	58	608	2e-20	106
rs:WP_023330550	MULTISPECIES: DNA topoisomerase 1 [Enterobacter].	24.27	585	384	18	76	633	82	634	2e-20	106
rs:WP_001933799	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	2e-20	106
rs:WP_047110804	DNA topoisomerase I [Brachyspira hyodysenteriae].	23.61	665	406	23	3	629	28	628	2e-20	106
rs:WP_005944379	DNA topoisomerase I [Faecalibacterium prausnitzii].	25.00	580	374	19	83	630	59	609	2e-20	106
rs:WP_044295331	DNA topoisomerase III [Pseudomonas amygdali].	28.62	297	190	7	347	629	218	506	2e-20	105
rs:WP_044295331	DNA topoisomerase III [Pseudomonas amygdali].	28.89	180	117	4	1	177	1	172	9e-15	87.8
rs:WP_042601494	DNA topoisomerase I [Haemophilus influenzae].	25.05	475	298	14	187	633	196	640	2e-20	106
rs:WP_005687215	topoisomerase I [Haemophilus influenzae].	25.05	475	298	14	187	633	196	640	2e-20	106
tr:E7PGW7_PSESG	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFW87203.1}; Flags: Fragment;	32.20	177	110	4	41	210	3	176	2e-20	100
rs:WP_015058546	DNA topoisomerase I [Streptococcus agalactiae].	24.69	559	351	22	103	630	99	618	2e-20	106
rs:WP_032837410	DNA topoisomerase I [Fusobacterium sp. CM1].	25.69	619	369	22	2	589	12	570	2e-20	106
rs:WP_027890873	DNA topoisomerase I [Megamonas hypermegale].	24.16	683	406	26	3	636	6	625	2e-20	106
rs:WP_027335956	DNA topoisomerase I [Halomonas sp. HL-48].	25.33	604	350	20	76	633	94	642	2e-20	106
rs:WP_020789377	DNA topoisomerase I [Fusobacterium nucleatum].	24.84	616	378	19	2	589	9	567	2e-20	106
rs:XP_009765587	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Nicotiana sylvestris].	22.09	670	442	24	3	631	6	636	2e-20	106
rs:WP_017099940	topoisomerase I [Vibrio tasmaniensis].	24.04	599	373	19	74	633	84	639	2e-20	106
rs:WP_018346637	topoisomerase I [Gallibacterium anatis].	23.86	591	383	17	74	633	86	640	2e-20	106
tr:X8IE43_9FUSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.69	619	369	22	2	589	9	567	2e-20	106
rs:WP_042415599	DNA topoisomerase I [Geomicrobium sp. JCM 19038].	24.26	577	367	22	90	629	67	610	2e-20	106
rs:WP_044939746	DNA topoisomerase I [Blautia schinkii].	23.65	613	363	23	90	630	67	646	2e-20	106
rs:WP_043040559	DNA topoisomerase I [Streptococcus equi].	24.18	579	369	21	83	630	84	623	2e-20	106
rs:WP_034769755	DNA topoisomerase I [Bacillus thermoamylovorans].	24.82	560	364	23	105	635	82	613	2e-20	106
rs:WP_012606724	DNA topoisomerase I [Acidithiobacillus ferrooxidans].	23.58	547	349	15	19	538	4	508	2e-20	106
rs:XP_002986296	hypothetical protein SELMODRAFT_123748, partial [Selaginella moellendorffii].	23.36	672	410	27	38	637	24	662	2e-20	106
rs:WP_039815909	DNA topoisomerase I [Xanthomonas arboricola].	24.61	573	344	20	3	538	5	526	2e-20	106
tr:M0V3B7_HORVD	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:MLOC_17646.3};	22.51	622	406	22	31	614	14	597	2e-20	106
rs:WP_044919789	DNA topoisomerase I [Lachnospiraceae bacterium MA2020].	23.81	714	435	26	2	675	4	648	2e-20	106
rs:WP_025492963	hypothetical protein, partial [Lachnospiraceae bacterium VE202-12].	33.65	211	127	5	467	671	15	218	2e-20	101
rs:WP_000179621	DNA topoisomerase I [Streptococcus sp. SK643].	24.14	580	365	22	83	629	71	608	2e-20	106
rs:WP_038184057	DNA topoisomerase I [Viridibacillus arenosi].	23.69	553	365	17	105	629	82	605	2e-20	106
rs:WP_044841803	DNA topoisomerase I [Thalassomonas viridans].	25.00	608	371	21	65	631	75	638	2e-20	106
rs:WP_036968862	DNA topoisomerase I [Pseudoalteromonas lipolytica].	24.08	623	387	23	52	631	62	641	2e-20	106
tr:G9QFT8_9BACI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHL65059.1};	38.19	144	86	2	3	143	4	147	2e-20	99.4
rs:XP_009414692	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Musa acuminata subsp. malaccensis].	23.08	624	392	25	3	586	6	581	2e-20	106
rs:WP_035634529	DNA topoisomerase I [Lachnospiraceae bacterium ND2006].	24.28	626	390	24	90	675	67	648	2e-20	106
rs:WP_045040343	DNA topoisomerase III, partial [Photobacterium iliopiscarium].	32.09	215	137	4	374	581	6	218	2e-20	101
rs:WP_022412909	DNA topoisomerase [Clostridium sp. CAG:470].	24.35	538	352	18	103	615	80	587	2e-20	106
rs:WP_025727922	DNA topoisomerase I [Bacillus ginsengihumi].	24.37	558	357	22	105	630	82	606	2e-20	106
tr:K8A3X1_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.47	609	364	23	73	633	88	648	2e-20	106
rs:WP_029221354	DNA topoisomerase I [Xanthomonas cassavae].	24.65	576	340	21	3	538	5	526	2e-20	106
rs:WP_016902511	DNA topoisomerase I [Xanthomonas arboricola].	24.61	573	344	20	3	538	5	526	2e-20	106
rs:WP_044979376	DNA topoisomerase I [Streptococcus suis].	23.40	577	374	18	83	629	72	610	2e-20	106
rs:WP_017121437	DNA topoisomerase I [Xanthomonas vasicola].	24.43	573	345	20	3	538	5	526	2e-20	106
rs:WP_005662215	topoisomerase I [Haemophilus influenzae].	25.05	475	298	14	187	633	196	640	2e-20	106
rs:WP_009765522	DNA topoisomerase I [Sporosarcina newyorkensis].	23.92	556	370	19	100	629	77	605	2e-20	106
rs:WP_012995298	DNA topoisomerase I [Thermoanaerobacter italicus].	24.92	590	344	21	90	629	67	607	2e-20	106
rs:WP_003547140	DNA topoisomerase I [Lactobacillus acidophilus].	24.78	569	353	22	103	635	93	622	2e-20	106
rs:WP_019165481	DNA topoisomerase I [Staphylococcus delphini].	24.78	573	362	22	90	629	67	603	2e-20	106
rs:WP_034842450	DNA topoisomerase I [[Clostridium] cellulosi].	24.12	622	388	25	90	671	67	644	2e-20	106
tr:W5EY12_WHEAT	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Traes_5AL_6C02AB5F8.2};	22.36	626	403	25	31	614	14	598	2e-20	106
rs:WP_004622029	DNA topoisomerase I [[Clostridium] papyrosolvens].	25.09	562	329	22	103	616	80	597	2e-20	106
rs:WP_021915113	GTP-sensing transcriptional pleiotropic repressor CodY [Firmicutes bacterium CAG:24].	24.46	560	352	19	90	616	67	588	2e-20	106
rs:WP_045035653	DNA topoisomerase I [Photobacterium iliopiscarium].	24.62	597	374	22	73	633	83	639	2e-20	106
rs:WP_005916915	DNA topoisomerase I [Fusobacterium hwasookii].	24.83	604	371	19	2	580	9	554	2e-20	106
rs:WP_029740526	DNA topoisomerase I [Enterobacter asburiae].	23.92	602	365	23	76	633	82	634	2e-20	106
rs:WP_022689888	DNA topoisomerase I [Sphingomonas-like bacterium B12].	22.72	669	422	23	1	629	1	614	2e-20	106
rs:WP_004286415	DNA topoisomerase I [Francisella philomiragia].	25.29	597	377	21	74	629	51	619	2e-20	106
rs:WP_019391804	MULTISPECIES: DNA topoisomerase I [Bacillus].	23.46	584	385	19	105	655	82	636	2e-20	105
rs:WP_007403904	MULTISPECIES: DNA topoisomerase I [Sphingomonas].	22.47	672	420	23	1	629	1	614	3e-20	106
rs:WP_040332936	DNA topoisomerase I, partial [Butyricicoccus pullicaecorum].	23.39	654	404	23	2	616	3	598	3e-20	105
rs:WP_043104942	DNA topoisomerase I [Xanthomonas arboricola].	24.61	573	344	20	3	538	5	526	3e-20	106
rs:WP_043087498	DNA topoisomerase I [Xanthomonas arboricola].	24.61	573	344	20	3	538	5	526	3e-20	106
rs:WP_043734521	DNA topoisomerase I [Lactococcus lactis].	25.18	556	350	20	103	629	103	621	3e-20	105
rs:WP_010696774	DNA topoisomerase I [Treponema denticola].	25.09	546	333	22	163	675	157	659	3e-20	105
rs:WP_034448315	DNA topoisomerase I [Cloacimonetes bacterium SCGC AAA252-E13].	27.44	583	346	23	83	629	60	601	3e-20	106
rs:WP_042490506	DNA topoisomerase I [Sphingomonas parapaucimobilis].	22.52	675	416	24	1	629	1	614	3e-20	106
gpu:CP009504_1119	DNA topoisomerase I [Methanosarcina sp. WH1]	24.89	458	299	16	188	629	196	624	3e-20	106
rs:WP_008956602	topoisomerase I [Halomonas sp. HAL1].	26.09	598	353	21	76	633	94	642	3e-20	106
tr:V5GTF2_IXORI	SubName: Full=Putative dna topoisomerase iii alpha {ECO:0000313|EMBL:JAB73695.1}; Flags: Fragment;	22.53	608	388	18	3	564	5	575	3e-20	106
tr:U2I1J4_LACPN	SubName: Full=Topoisomerase I {ECO:0000313|EMBL:ERJ61682.1}; Flags: Fragment;	34.11	214	123	7	3	203	5	213	3e-20	100
rs:WP_009138456	DNA topoisomerase [Slackia piriformis].	24.83	572	344	23	83	616	126	649	3e-20	106
rs:WP_004848998	MULTISPECIES: DNA topoisomerase I [Coprococcus].	26.24	564	337	22	90	616	67	588	3e-20	105
rs:WP_045655781	DNA topoisomerase I [Hyphomonadaceae bacterium BRH_c29].	24.19	682	408	29	1	629	1	626	3e-20	106
rs:WP_044593298	hypothetical protein [Cronobacter sakazakii].	36.49	148	90	2	437	581	9	155	3e-20	100
rs:WP_007049396	DNA topoisomerase I [Anaerofustis stercorihominis].	26.03	580	343	22	100	635	77	614	3e-20	105
rs:WP_005588136	DNA topoisomerase I [Clostridium ultunense].	24.69	567	360	23	103	635	80	613	3e-20	105
rs:WP_020814402	DNA topoisomerase I [[Clostridium] papyrosolvens].	24.26	573	346	19	90	616	67	597	3e-20	105
rs:WP_028989890	DNA topoisomerase I [Thermithiobacillus tepidarius].	23.47	669	418	25	2	630	4	618	3e-20	106
rs:WP_043864567	DNA topoisomerase I [Pseudomonas putida].	24.54	599	367	23	74	633	85	637	3e-20	106
rs:WP_024395842	DNA topoisomerase I [Streptococcus suis].	23.62	580	369	21	83	629	72	610	3e-20	105
rs:WP_023335949	DNA topoisomerase 1 [Enterobacter sp. MGH 24].	23.92	602	365	23	76	633	82	634	3e-20	106
rs:WP_012603610	topoisomerase I [Vibrio tasmaniensis].	23.71	599	375	18	74	633	84	639	3e-20	106
rs:WP_015232833	DNA topoisomerase I, archaeal [Caldisphaera lagunensis].	26.21	641	399	23	4	612	18	616	3e-20	105
rs:WP_028329924	DNA topoisomerase I [Brachyspira alvinipulli].	23.36	672	399	24	3	629	31	631	3e-20	105
tr:A0A0C7C5P2_9FUNG	SubName: Full=RMATCC62417_13354 protein {ECO:0000313|EMBL:CEG78805.1};	22.59	726	460	30	3	672	7	686	3e-20	106
rs:WP_045750540	DNA topoisomerase I [Methylophilaceae bacterium MMS-10A-171].	24.27	647	401	22	2	614	3	594	3e-20	106
rs:WP_031824418	DNA topoisomerase I [Staphylococcus aureus].	24.30	568	371	17	90	629	67	603	3e-20	105
rs:WP_012881931	DNA topoisomerase I [Dehalococcoides mccartyi].	25.07	674	387	26	2	624	4	610	3e-20	105
rs:WP_041405792	DNA topoisomerase I [Shewanella denitrificans].	23.17	643	423	21	65	673	76	681	3e-20	106
rs:WP_024304701	DNA topoisomerase I [Cloacimonetes bacterium SCGC AAA252-N11].	27.44	583	346	23	83	629	60	601	3e-20	105
rs:WP_045978387	DNA topoisomerase I [Pseudoalteromonas ruthenica].	24.80	633	370	25	52	631	62	641	3e-20	106
rs:WP_025052246	DNA topoisomerase I [Sulfitobacter sp. NB-68].	24.19	554	352	16	1	534	1	506	3e-20	106
rs:WP_033794942	DNA topoisomerase I, partial [Bacillus sp. 105MF].	30.85	282	168	11	3	268	5	275	3e-20	102
gp:CP000408_998	DNA topoisomerase I [Streptococcus suis 98HAH33]	23.22	577	375	18	83	629	24	562	3e-20	105
rs:WP_040466951	DNA topoisomerase I [Eubacterium brachy].	25.43	582	356	24	90	635	61	600	3e-20	105
tr:X1LU46_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_C00382 {ECO:0000313|EMBL:GAH97648.1}; Flags: Fragment;	24.13	489	300	14	188	643	3	453	3e-20	104
rs:WP_026570374	MULTISPECIES: DNA topoisomerase I [Bacillaceae].	25.49	565	354	22	105	635	82	613	3e-20	105
rs:WP_025254952	DNA topoisomerase I [Alteromonas sp. ALT199].	25.93	617	352	26	65	629	75	638	3e-20	106
rs:WP_014313953	DNA topoisomerase I [Clostridium sp. BNL1100].	25.09	562	329	22	103	616	80	597	3e-20	105
rs:WP_037545865	DNA topoisomerase I [Staphylococcus lugdunensis].	24.91	558	354	20	103	629	80	603	3e-20	105
rs:WP_047210202	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	3e-20	105
rs:WP_002485347	DNA topoisomerase I [Staphylococcus epidermidis].	24.33	559	362	18	100	629	77	603	3e-20	105
rs:WP_000520432	topoisomerase I [Vibrio cholerae].	24.13	605	363	22	75	633	87	641	3e-20	106
rs:WP_026375035	DNA topoisomerase I [Aestuariibacter salexigens].	24.88	607	371	19	65	629	75	638	3e-20	106
tr:E4X5F4_OIKDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.89	607	373	22	3	564	5	567	3e-20	106
rs:WP_036806692	DNA topoisomerase I [Planomicrobium glaciei].	25.83	569	338	23	103	630	80	605	3e-20	105
rs:WP_028770836	DNA topoisomerase I [Silanimonas lenta].	22.94	693	411	25	3	639	5	630	3e-20	106
rs:WP_012545297	DNA topoisomerase I [Thermodesulfovibrio yellowstonii].	26.89	595	340	22	89	629	66	619	3e-20	105
rs:WP_013150348	DNA topoisomerase I [Thermoanaerobacter mathranii].	25.47	589	342	23	90	629	67	607	3e-20	105
rs:WP_011160653	topoisomerase I [Onion yellows phytoplasma].	25.88	568	350	19	88	629	65	587	3e-20	105
rs:WP_024791594	DNA topoisomerase I [Lebetimonas sp. JS032].	25.45	660	391	27	3	629	5	596	3e-20	105
rs:WP_046864111	DNA topoisomerase [Microvirga sp. JC119].	22.61	637	406	23	33	602	26	642	3e-20	105
rs:WP_034436080	DNA topoisomerase I [Clostridiales bacterium S5-A11].	23.51	706	429	23	3	671	37	668	3e-20	105
rs:WP_012942649	DNA topoisomerase I [Haloterrigena turkmenica].	21.64	730	441	28	1	661	1	668	3e-20	105
tr:A0A090SK27_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL27228.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL27228.1};	33.33	162	108	0	420	581	30	191	3e-20	101
rs:WP_003139282	DNA topoisomerase I [Lactococcus raffinolactis].	25.43	586	366	26	83	639	92	635	3e-20	105
rs:WP_017076459	topoisomerase I [Vibrio splendidus].	23.54	599	376	18	74	633	84	639	3e-20	106
rs:WP_002459295	DNA topoisomerase I [Staphylococcus lugdunensis].	24.91	558	354	20	103	629	80	603	3e-20	105
rs:WP_033609470	topoisomerase I, partial [Lactobacillus plantarum].	29.49	217	142	5	351	560	1	213	3e-20	100
rs:WP_035709424	DNA topoisomerase I [Haematobacter massiliensis].	24.73	643	368	26	55	630	27	620	3e-20	106
tr:Q12LR8_SHEDO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.17	643	423	21	65	673	92	697	3e-20	106
gpu:CP009503_1191	DNA topoisomerase I [Methanosarcina sp. WWM596]	24.68	462	295	17	188	629	196	624	3e-20	105
rs:WP_043895033	DNA topoisomerase I [Streptococcus lutetiensis].	23.84	562	352	23	103	630	105	624	3e-20	105
rs:WP_035596172	DNA topoisomerase I [Halomonas salina].	25.20	488	283	17	186	633	201	646	3e-20	105
rs:WP_042535048	DNA topoisomerase I [Oceanobacillus oncorhynchi].	23.73	573	385	18	90	635	67	614	3e-20	105
rs:WP_011890947	DNA topoisomerase I [Chlorobium phaeovibrioides].	25.24	614	367	22	77	637	64	638	3e-20	105
rs:WP_028018800	DNA topoisomerase I [Enterobacter cloacae].	24.17	600	366	21	76	633	82	634	3e-20	105
rs:WP_032885958	DNA topoisomerase I, partial [Fusobacterium nucleatum].	25.69	619	369	22	2	589	12	570	3e-20	105
rs:WP_042092685	hypothetical protein, partial [Escherichia coli].	28.53	319	206	6	284	581	52	369	3e-20	103
rs:WP_001286956	DNA topoisomerase I [Bacillus thuringiensis].	23.88	582	384	21	105	655	82	635	3e-20	105
rs:WP_041607638	DNA topoisomerase I [Halobacteroides halobius].	24.63	609	382	23	100	675	84	648	3e-20	105
tr:D4IVN0_BUTFI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.11	564	365	17	83	616	60	590	3e-20	105
rs:WP_047043504	DNA topoisomerase I [Vibrio sp. CAIM 1540].	24.58	598	373	17	73	633	83	639	3e-20	105
rs:WP_021240303	MULTISPECIES: topoisomerase I [Enterobacter].	24.17	600	366	21	76	633	82	634	3e-20	105
rs:WP_005896639	DNA topoisomerase I [Fusobacterium nucleatum].	24.46	695	434	22	2	671	12	640	3e-20	105
rs:WP_039266524	DNA topoisomerase I [Enterobacter sp. FB].	24.17	600	366	21	76	633	82	634	3e-20	105
tr:S5QX37_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.84	562	352	23	103	630	123	642	3e-20	105
rs:WP_043518096	DNA topoisomerase I [Halomonas sp. BC04].	25.21	484	284	15	186	633	201	642	3e-20	105
rs:WP_012063858	DNA topoisomerase I [Alkaliphilus metalliredigens].	23.98	659	408	21	3	629	5	602	3e-20	105
rs:WP_047192026	DNA topoisomerase [Microvirga vignae].	24.13	634	392	28	44	609	27	639	3e-20	105
rs:WP_023292242	DNA topoisomerase 1 [Enterobacter cloacae].	24.17	600	366	21	76	633	82	634	3e-20	105
tr:F6I488_VITVI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.64	614	398	19	54	631	21	593	4e-20	105
tr:R1YY17_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOF91245.1}; Flags: Fragment;	26.72	262	183	4	376	629	2	262	4e-20	102
rs:WP_006723677	DNA topoisomerase [Collinsella intestinalis].	23.26	559	358	20	87	616	134	650	4e-20	105
rs:WP_022628183	DNA topoisomerase I [Bacillus marmarensis].	24.37	554	366	19	103	630	80	606	4e-20	105
rs:WP_016647809	DNA topoisomerase I [Facklamia hominis].	24.61	577	354	22	90	629	68	600	4e-20	105
tr:B8IEL1_METNO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.63	548	346	22	33	520	26	555	4e-20	105
tr:U6PAL2_HAECO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.99	609	384	19	3	564	42	612	4e-20	105
rs:WP_039164285	DNA topoisomerase I [Gallibacterium anatis].	23.48	592	384	18	74	633	86	640	4e-20	105
tr:L2IN04_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELA69015.1};	26.14	352	225	7	186	514	36	375	4e-20	102
rs:WP_045050014	DNA topoisomerase I [Chromobacterium violaceum].	23.80	584	376	17	84	630	61	612	4e-20	105
rs:WP_011137815	DNA topoisomerase I [Chromobacterium violaceum].	23.80	584	376	17	84	630	61	612	4e-20	105
tr:H5SLA0_9CHLR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.54	599	383	24	77	630	74	636	4e-20	105
rs:WP_011307376	DNA topoisomerase I [Methanosarcina barkeri].	24.95	461	295	19	188	629	196	624	4e-20	105
rs:XP_006492982	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X1 [Citrus sinensis].	22.33	712	421	24	3	631	7	669	4e-20	105
rs:WP_027872316	DNA topoisomerase I [[Eubacterium] cellulosolvens].	24.02	562	352	18	90	616	67	588	4e-20	105
rs:WP_002478284	DNA topoisomerase I [Staphylococcus lugdunensis].	24.91	558	354	20	103	629	80	603	4e-20	105
rs:WP_040146339	DNA topoisomerase I [Legionella pneumophila].	25.60	668	412	32	55	673	29	660	4e-20	105
rs:WP_045630538	DNA topoisomerase I [Enterobacter cloacae].	24.02	587	383	20	76	633	82	634	4e-20	105
rs:WP_032882171	DNA topoisomerase I [Fusobacterium nucleatum].	24.88	603	372	19	2	580	9	554	4e-20	105
rs:WP_041064938	DNA topoisomerase I [Thiolapillus brandeum].	23.91	573	342	19	1	534	1	518	4e-20	105
rs:WP_043618220	DNA topoisomerase I [Chromobacterium violaceum].	23.80	584	376	17	84	630	61	612	4e-20	105
rs:WP_000179640	DNA topoisomerase I [Streptococcus pneumoniae].	23.70	578	370	18	83	629	71	608	4e-20	105
rs:WP_024782601	DNA topoisomerase I [Streptococcus mutans].	23.88	582	367	22	83	630	78	617	4e-20	105
rs:WP_023344331	MULTISPECIES: DNA topoisomerase 1 [Enterobacter cloacae complex].	24.17	600	366	21	76	633	82	634	4e-20	105
rs:WP_003332525	DNA topoisomerase I [Bacillus azotoformans].	24.10	556	361	18	105	629	82	607	4e-20	105
rs:WP_014052595	DNA topoisomerase I [halophilic archaeon DL31].	23.07	724	445	30	1	661	1	675	4e-20	105
tr:C3IN36_BACTU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.88	582	384	21	105	655	41	594	4e-20	105
rs:WP_013979502	DNA topoisomerase [Eggerthella sp. YY7918].	24.11	535	344	19	65	571	111	611	4e-20	105
rs:WP_037552772	DNA topoisomerase I [Sphingomonas sp. URHD0057].	22.69	670	421	24	1	629	1	614	4e-20	105
tr:C3I4V3_BACTU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.88	582	384	21	105	655	52	605	4e-20	105
rs:WP_001716542	DNA topoisomerase III, partial [Salmonella enterica].	28.24	301	185	9	1	280	1	291	4e-20	102
rs:WP_004396182	MULTISPECIES: DNA topoisomerase I [Thermoanaerobacter].	24.91	582	354	21	90	629	67	607	4e-20	105
rs:WP_017111054	topoisomerase I [Vibrio tasmaniensis].	24.34	604	367	20	73	633	83	639	4e-20	105
rs:XP_001449675	hypothetical protein [Paramecium tetraurelia strain d4-2].	23.90	611	390	25	3	574	33	607	4e-20	105
rs:XP_010650402	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Vitis vinifera].	22.64	614	398	19	54	631	6	578	4e-20	105
rs:WP_012739047	DNA topoisomerase I [[Eubacterium] eligens].	23.87	574	338	20	90	616	67	588	4e-20	105
rs:XP_010160349	PREDICTED: DNA topoisomerase 3-beta-1 [Caprimulgus carolinensis].	23.06	607	386	19	3	564	5	575	4e-20	105
rs:WP_025046431	DNA topoisomerase I [Sulfitobacter mediterraneus].	22.02	713	444	21	1	658	1	656	4e-20	105
rs:WP_014884091	topoisomerase I [Enterobacter cloacae].	24.27	585	384	18	76	633	82	634	4e-20	105
rs:WP_045135520	DNA topoisomerase I [Enterobacter cloacae].	24.27	585	384	18	76	633	82	634	4e-20	105
rs:WP_042401695	hypothetical protein [Geomicrobium sp. JCM 19037].	32.43	222	144	4	465	680	39	260	4e-20	101
tr:C3FP15_BACTB	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.71	582	385	20	105	655	75	628	4e-20	105
rs:WP_033843509	DNA topoisomerase I [Geobacillus subterraneus].	25.24	511	323	19	157	636	132	614	4e-20	105
rs:WP_001286957	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	23.88	582	384	21	105	655	82	635	4e-20	105
rs:WP_047365954	DNA topoisomerase I [Enterobacter sp. GN03191].	24.27	585	384	18	76	633	82	634	4e-20	105
tr:L8JIZ1_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.87	591	372	17	76	633	58	609	4e-20	105
rs:WP_022945094	topoisomerase I [Pseudoalteromonas ruthenica].	24.80	633	370	25	52	631	62	641	4e-20	105
rs:WP_002448837	DNA topoisomerase I [Staphylococcus hominis].	25.81	558	355	21	100	629	77	603	4e-20	105
tr:A6BH91_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.84	558	360	19	90	616	71	594	4e-20	105
tr:A0A0D6G271_FUSNP	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:CKG90094.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CKG90094.1};	25.12	617	375	21	2	589	9	567	4e-20	105
rs:WP_045098244	DNA topoisomerase I [Tatlockia micdadei].	26.30	635	364	33	55	630	29	618	4e-20	105
rs:WP_039424352	DNA topoisomerase I, partial [Porphyromonas gulae].	33.66	205	126	4	166	368	2	198	4e-20	100
rs:WP_047348265	DNA topoisomerase I [Enterobacter sp. GN03164].	24.05	607	358	21	76	633	82	634	4e-20	105
tr:L0K918_HALHC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.63	609	382	23	100	675	79	643	4e-20	105
rs:WP_000246614	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	4e-20	105
rs:WP_005902939	DNA topoisomerase I [Fusobacterium nucleatum].	25.00	604	370	20	2	580	12	557	4e-20	105
rs:WP_002032552	DNA topoisomerase I [Vibrio cholerae].	24.13	605	363	22	75	633	87	641	4e-20	105
tr:D2EGP7_PARA4	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.56	574	359	22	89	630	111	642	4e-20	105
rs:WP_043751848	DNA topoisomerase [Methylobacterium nodulans].	22.63	548	346	22	33	520	17	546	4e-20	105
rs:WP_008502813	MULTISPECIES: topoisomerase I [Enterobacter].	24.17	600	366	21	76	633	82	634	4e-20	105
tr:W4QCN6_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE29722.1};	38.56	153	87	3	465	615	20	167	4e-20	101
rs:WP_012276709	topoisomerase I [Shewanella halifaxensis].	25.58	520	288	18	163	633	175	644	4e-20	105
rs:WP_038439819	DNA topoisomerase I [Fusobacterium nucleatum].	24.84	616	378	20	2	589	9	567	4e-20	105
rs:WP_036798385	DNA topoisomerase I [Photobacterium sp. AK15].	24.87	591	372	17	76	633	88	639	4e-20	105
rs:XP_011073926	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Sesamum indicum].	23.28	670	434	24	3	631	6	636	4e-20	105
rs:WP_012677973	DNA topoisomerase I [Streptococcus equi].	24.31	576	372	20	83	630	84	623	4e-20	105
rs:XP_005183987	PREDICTED: DNA topoisomerase 3-beta [Musca domestica].	22.95	597	385	21	3	560	5	565	4e-20	105
rs:WP_032849228	DNA topoisomerase I, partial [Fusobacterium nucleatum].	25.69	619	369	22	2	589	9	567	4e-20	105
rs:WP_033022990	DNA topoisomerase I [Geobacillus sp. G1w1].	25.24	511	323	19	157	636	132	614	4e-20	105
rs:WP_001286968	DNA topoisomerase I [Bacillus thuringiensis].	24.42	561	365	21	105	635	82	613	4e-20	105
rs:WP_027971276	DNA topoisomerase I [Streptococcus plurextorum].	24.39	578	354	23	90	630	85	616	4e-20	105
rs:WP_016961327	topoisomerase I [Enterovibrio norvegicus].	24.84	608	355	21	74	633	86	639	4e-20	105
rs:WP_012154784	topoisomerase I [Shewanella pealeana].	24.65	507	309	15	163	633	175	644	4e-20	105
rs:WP_017650225	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	4e-20	105
rs:WP_010569406	DNA topoisomerase I [Leptospira broomii].	23.81	630	378	22	55	630	28	609	4e-20	105
tr:A0A0D6PQ44_9PROT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAN89483.1};	22.88	638	396	23	55	629	28	632	4e-20	105
rs:WP_015072720	DNA topoisomerase I [Gluconobacter oxydans].	22.88	638	396	23	55	629	28	632	4e-20	105
gpu:CP006256_3668	Topoisomerase IA [Pseudomonas syringae pv. syringae HS191]	28.85	253	158	8	1	242	1	242	4e-20	103
gpu:CP006256_3668	Topoisomerase IA [Pseudomonas syringae pv. syringae HS191]	35.17	145	81	4	189	321	273	416	8e-12	78.2
rs:WP_032976671	DNA topoisomerase I [Stenotrophomonas sp. RIT309].	24.70	579	337	20	3	538	5	527	4e-20	105
tr:A0A061NPP8_9BACL	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAK04500.1};	32.43	222	144	4	465	680	33	254	4e-20	101
rs:WP_026669942	DNA topoisomerase I [Butyrivibrio sp. AE3006].	24.16	563	352	17	90	616	70	593	5e-20	105
rs:WP_025879065	DNA topoisomerase I [Stenotrophomonas maltophilia].	24.70	579	337	20	3	538	5	527	5e-20	105
rs:WP_033832335	DNA topoisomerase I [Stenotrophomonas maltophilia].	24.70	579	337	20	3	538	5	527	5e-20	105
rs:WP_000520436	MULTISPECIES: topoisomerase I [Vibrio].	23.98	613	374	21	57	633	85	641	5e-20	105
rs:WP_023041398	DNA topoisomerase I [Fusobacterium nucleatum].	25.00	604	370	20	2	580	9	554	5e-20	105
rs:WP_016480750	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	5e-20	105
rs:WP_020367886	DNA topoisomerase I, partial [Staphylococcus epidermidis].	24.14	555	360	18	104	629	1	523	5e-20	104
rs:WP_016230148	DNA topoisomerase I [Lachnospiraceae bacterium 10-1].	25.37	607	372	22	103	673	80	641	5e-20	105
rs:WP_001286955	MULTISPECIES: DNA topoisomerase I [Bacillus].	23.71	582	385	20	105	655	82	635	5e-20	105
rs:XP_011696596	PREDICTED: DNA topoisomerase 3-beta-1 [Wasmannia auropunctata].	22.45	677	440	22	3	630	5	645	5e-20	105
rs:WP_032583509	DNA topoisomerase I, partial [Bacteroides fragilis].	31.53	222	141	7	457	675	7	220	5e-20	100
rs:XP_001026048	DNA topoisomerase I [Tetrahymena thermophila SB210].	23.89	699	425	27	3	640	538	1190	5e-20	105
rs:WP_037326601	DNA topoisomerase I [Anaerococcus lactolyticus].	24.50	649	380	28	3	614	5	580	5e-20	105
rs:WP_039263555	MULTISPECIES: DNA topoisomerase I [Enterobacter].	23.75	602	366	23	76	633	82	634	5e-20	105
rs:WP_001286967	DNA topoisomerase I [Bacillus cereus].	24.24	561	366	21	105	635	82	613	5e-20	105
gp:CP010942_735	DNA topoisomerase I [Staphylococcus epidermidis]	24.15	559	363	18	100	629	77	603	5e-20	105
rs:WP_022164626	DNA topoisomerase [Eubacterium sp. CAG:192].	22.20	644	410	18	3	616	5	587	5e-20	105
tr:A0A067B5R6_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.81	609	380	19	57	633	85	641	5e-20	105
rs:WP_039083418	DNA topoisomerase I [Gallibacterium anatis].	23.38	586	392	14	74	633	86	640	5e-20	105
rs:XP_009665048	PREDICTED: DNA topoisomerase 3-beta-1 [Struthio camelus australis].	22.90	607	387	19	3	564	5	575	5e-20	105
rs:WP_017089558	topoisomerase I [Vibrio splendidus].	23.55	603	371	19	74	633	84	639	5e-20	105
rs:WP_039574954	DNA topoisomerase III, partial [Xanthomonas axonopodis].	30.30	231	144	7	1	222	1	223	5e-20	100
rs:WP_032640977	DNA topoisomerase I [Enterobacter cloacae].	24.17	600	366	21	76	633	82	634	5e-20	105
tr:R5I715_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.73	546	341	23	103	616	80	587	5e-20	105
rs:WP_027081690	DNA topoisomerase I [Lysobacter sp. URHA0019].	24.91	578	336	23	3	538	5	526	5e-20	105
rs:WP_005729974	hypothetical protein [Lactobacillus crispatus].	23.58	742	458	25	44	685	46	778	5e-20	105
rs:WP_012971263	DNA topoisomerase I [Allochromatium vinosum].	24.45	679	403	30	1	630	1	618	5e-20	105
tr:C2VXP8_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.24	561	366	21	105	635	52	583	5e-20	105
rs:WP_041111666	DNA topoisomerase I [Gluconobacter oxydans].	23.05	655	402	24	38	629	17	632	5e-20	105
rs:WP_041909639	MULTISPECIES: DNA topoisomerase I [Enterobacter].	24.02	587	383	20	76	633	82	634	5e-20	105
tr:M1ZP81_CLOBO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKN40186.1}; Flags: Fragment;	34.44	180	109	5	68	243	1	175	5e-20	99.4
rs:WP_014062912	DNA topoisomerase I [Thermoanaerobacter wiegelii].	24.58	590	346	21	90	629	67	607	5e-20	105
rs:WP_042317180	DNA topoisomerase III, partial [Desulfotomaculum acetoxidans].	30.35	257	170	5	422	675	8	258	5e-20	102
rs:WP_045638320	DNA topoisomerase I, partial [Peptococcaceae bacterium BRH_c4a].	23.29	657	390	22	3	616	10	595	5e-20	105
rs:WP_000520438	topoisomerase I [Vibrio sp. RC341].	23.81	609	380	19	57	633	85	641	5e-20	105
rs:WP_000246608	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	5e-20	105
rs:WP_015615734	DNA topoisomerase I [Clostridium pasteurianum].	24.35	649	391	21	3	616	5	588	5e-20	105
rs:WP_013297943	DNA topoisomerase I [Thermoanaerobacterium thermosaccharolyticum].	25.93	617	374	24	90	669	67	637	5e-20	105
tr:K2EI12_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.10	697	417	28	1	639	1	643	5e-20	105
rs:WP_004603702	DNA topoisomerase I [[Eubacterium] cellulosolvens].	23.60	555	363	15	90	616	67	588	5e-20	105
rs:XP_010218989	PREDICTED: DNA topoisomerase 3-beta-1 [Tinamus guttatus].	22.90	607	387	19	3	564	5	575	5e-20	105
rs:WP_037578240	DNA topoisomerase I [Streptococcus equi].	24.18	579	369	21	83	630	84	623	5e-20	105
rs:WP_010370069	DNA topoisomerase I [Xanthomonas vasicola].	24.43	573	345	20	3	538	5	526	5e-20	105
rs:WP_028991696	DNA topoisomerase I [Thermoanaerobacter thermocopriae].	25.47	589	342	23	90	629	67	607	5e-20	105
rs:WP_047146216	DNA topoisomerase I [Mesorhizobium sp. LC103].	22.93	724	396	30	1	643	1	643	5e-20	105
rs:WP_000246611	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	5e-20	105
rs:WP_023427494	DNA topoisomerase I, archaeal [uncultured Acidilobus sp. OSP8].	24.60	561	360	19	4	540	15	536	5e-20	105
rs:WP_032549444	DNA topoisomerase I [Vibrio fortis].	24.37	599	369	19	75	633	85	639	5e-20	105
rs:WP_042738862	DNA topoisomerase I [Staphylococcus gallinarum].	23.77	551	368	17	103	629	80	602	5e-20	105
rs:WP_000246607	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	5e-20	105
rs:WP_043951823	hypothetical protein, partial [Enterococcus faecium].	30.74	296	182	8	3	280	4	294	5e-20	101
rs:WP_046222745	DNA topoisomerase I [Vibrio sp. ECSMB14106].	23.68	604	369	19	74	633	84	639	5e-20	105
rs:WP_000246610	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	5e-20	105
rs:WP_029140909	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	5e-20	105
tr:W1ESZ2_ECOLX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CDL25211.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDL25211.1};	31.31	198	126	4	418	608	28	222	5e-20	100
rs:XP_001025000	DNA topoisomerase I [Tetrahymena thermophila SB210].	24.03	670	412	23	3	614	245	875	5e-20	105
rs:XP_002597412	hypothetical protein BRAFLDRAFT_80591 [Branchiostoma floridae].	23.01	678	435	22	3	631	5	644	5e-20	105
rs:WP_000246605	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	5e-20	105
rs:WP_015631990	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	5e-20	105
rs:XP_006021587	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Alligator sinensis].	22.73	607	388	18	3	564	5	575	5e-20	105
rs:XP_012455605	PREDICTED: DNA topoisomerase 3-beta isoform X3 [Gossypium raimondii].	24.75	509	320	19	105	586	25	497	5e-20	105
rs:XP_004248022	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Solanum lycopersicum].	22.09	670	442	24	3	631	6	636	5e-20	105
rs:WP_017646538	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	5e-20	105
rs:WP_000246603	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	6e-20	105
rs:WP_038144779	DNA topoisomerase I [Thioclava sp. 13D2W-2].	22.95	684	408	26	1	630	1	619	6e-20	105
tr:B7A9J7_THEAQ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.88	627	369	24	77	630	76	673	6e-20	105
rs:WP_017644456	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	6e-20	105
rs:WP_037597010	DNA topoisomerase I [Streptococcus sp. AS20].	24.09	577	369	22	83	629	70	607	6e-20	104
tr:B2KBN6_ELUMP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.43	704	396	29	3	643	20	657	6e-20	105
rs:WP_040684450	DNA topoisomerase I [Thermus aquaticus].	24.88	627	369	24	77	630	64	661	6e-20	105
tr:G4WVT3_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.08	622	392	23	76	676	54	622	6e-20	105
rs:WP_021655081	DNA topoisomerase I [Clostridiales bacterium oral taxon 876].	25.95	551	329	19	103	616	80	588	6e-20	104
tr:R8VV53_9CLOT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.39	654	404	23	2	616	3	598	6e-20	105
rs:WP_026524285	DNA topoisomerase I [Butyrivibrio sp. MB2005].	24.16	563	352	17	90	616	70	593	6e-20	104
rs:WP_000246615	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	6e-20	104
rs:WP_031502913	DNA topoisomerase I [Pseudothermotoga hypogea].	23.46	635	394	20	2	616	4	566	6e-20	105
tr:F2QD08_STROU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.62	563	359	20	83	616	71	591	6e-20	104
rs:WP_038094767	hypothetical protein, partial [Tumebacillus flagellatus].	24.51	657	384	25	3	615	5	593	6e-20	104
rs:WP_047061015	DNA topoisomerase I [Enterobacter asburiae].	23.75	602	366	23	76	633	82	634	6e-20	105
rs:WP_000246609	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	6e-20	104
tr:W1FZV9_ECOLX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CDL39904.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDL39904.1};	33.14	172	115	0	410	581	7	178	6e-20	100
rs:WP_045329359	DNA topoisomerase I [Enterobacter asburiae].	23.92	602	365	23	76	633	82	634	6e-20	105
rs:XP_011073925	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Sesamum indicum].	23.28	670	434	25	3	631	6	636	6e-20	105
rs:WP_014714499	DNA topoisomerase I [Francisella noatunensis].	24.52	624	401	20	74	656	51	645	6e-20	105
gpu:CP010867_998	DNA topoisomerase 1 [Streptococcus agalactiae]	24.51	559	352	22	103	630	102	621	6e-20	104
rs:XP_001388324	DNA topoisomerase III beta-1 [Cryptosporidium parvum Iowa II].	24.43	610	371	24	3	564	7	574	6e-20	105
rs:WP_013441072	DNA topoisomerase I [Methylovorus sp. MP688].	23.56	675	409	26	2	630	3	616	6e-20	105
rs:WP_005987997	DNA topoisomerase I [Xanthomonas vesicatoria].	24.43	573	345	20	3	538	5	526	6e-20	105
rs:WP_004828589	DNA topoisomerase I [Anaerococcus lactolyticus].	24.50	649	380	28	3	614	5	580	6e-20	104
rs:WP_000246613	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	6e-20	104
rs:WP_017055037	topoisomerase I [Vibrio kanaloae].	23.68	604	369	19	74	633	84	639	6e-20	105
rs:WP_035557252	DNA topoisomerase I [Halomonas sp. KO116].	25.92	598	354	21	76	633	94	642	6e-20	105
rs:WP_007283133	DNA topoisomerase I [Gluconobacter thailandicus].	22.88	638	396	23	55	629	28	632	6e-20	105
rs:WP_005337825	DNA topoisomerase I [Dorea formicigenerans].	23.71	620	389	22	90	671	67	640	6e-20	104
rs:WP_019316381	DNA topoisomerase I [Streptococcus mutans].	23.71	582	368	22	83	630	78	617	6e-20	104
rs:WP_014614088	DNA topoisomerase I [Staphylococcus pseudintermedius].	24.56	574	362	21	90	629	67	603	6e-20	104
rs:WP_015082465	DNA topoisomerase I [Lactococcus lactis].	25.00	556	351	20	103	629	101	619	6e-20	104
rs:WP_002305945	DNA topoisomerase I [Streptococcus mutans].	23.54	582	369	21	83	630	78	617	6e-20	104
rs:WP_002275215	DNA topoisomerase I [Streptococcus mutans].	23.84	583	366	23	83	630	78	617	6e-20	104
rs:WP_020612107	DNA topoisomerase I [Spirochaeta bajacaliforniensis].	25.61	578	330	21	3	530	6	533	6e-20	105
rs:WP_046835605	hypothetical protein, partial [Pseudomonas amygdali].	31.58	190	120	4	41	223	6	192	6e-20	100
rs:WP_013361711	DNA topoisomerase I [[Clostridium] sticklandii].	23.46	665	402	25	3	629	5	600	6e-20	104
rs:WP_014563693	DNA topoisomerase I [Lactobacillus helveticus].	24.87	571	350	21	103	635	93	622	6e-20	104
rs:WP_047186038	DNA topoisomerase I [Bacilli bacterium VT-13-104].	25.30	581	365	24	90	635	67	613	6e-20	104
rs:WP_000246600	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	6e-20	104
rs:WP_038655542	DNA topoisomerase I [Mucinivorans hirudinis].	22.97	592	379	18	1	580	1	527	6e-20	105
rs:WP_017105774	topoisomerase I [Vibrio tasmaniensis].	23.33	600	378	18	73	633	83	639	6e-20	105
rs:WP_022557737	hypothetical protein [Xanthomonas fuscans].	30.30	231	144	7	1	222	1	223	6e-20	101
rs:WP_022124364	DNA topoisomerase [Clostridium sp. CAG:510].	24.27	618	391	19	90	673	106	680	6e-20	104
rs:WP_033145741	DNA topoisomerase I [Enterobacter cloacae].	23.75	602	366	23	76	633	82	634	7e-20	105
tr:E5VTX7_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.40	658	386	24	3	616	5	588	7e-20	104
rs:WP_019183580	DNA topoisomerase I [Stenotrophomonas maltophilia].	24.61	581	335	21	3	538	5	527	7e-20	105
tr:V6M7K9_9EUKA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.89	653	416	18	3	612	4	618	7e-20	105
rs:WP_027966615	DNA topoisomerase I [Halomonas halocynthiae].	25.25	594	360	22	76	631	94	641	7e-20	105
rs:WP_012211826	DNA topoisomerase I [Lactobacillus helveticus].	24.87	571	350	21	103	635	93	622	7e-20	104
rs:WP_001286965	DNA topoisomerase I [Bacillus cereus].	24.24	561	366	21	105	635	82	613	7e-20	104
gpu:CP007601_554	DNA topoisomerase 1 [Staphylococcus capitis subsp. capitis]	24.46	556	359	20	103	629	80	603	7e-20	104
rs:WP_018362460	DNA topoisomerase I [Prevotella nanceiensis].	25.04	595	362	19	3	578	5	534	7e-20	104
rs:YP_029935	DNA topoisomerase I [Bacillus anthracis str. Sterne].	24.24	561	366	21	105	635	82	613	7e-20	104
rs:WP_017647390	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	7e-20	104
rs:WP_029731298	DNA topoisomerase I [Dorea sp. AGR2135].	23.71	620	389	22	90	671	67	640	7e-20	104
rs:WP_002276719	DNA topoisomerase I [Streptococcus mutans].	23.71	582	368	22	83	630	78	617	7e-20	104
rs:WP_039696903	DNA topoisomerase I [Streptococcus equinus].	23.84	562	352	23	103	630	105	624	7e-20	104
rs:WP_010269604	DNA topoisomerase I [Paenibacillus senegalensis].	25.09	574	352	23	103	636	80	615	7e-20	104
rs:WP_005587787	DNA topoisomerase I [Clostridium ultunense].	24.87	563	348	16	90	616	67	590	7e-20	104
tr:A0A077TXL4_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.12	568	372	17	90	629	69	605	7e-20	104
tr:C2FZU8_9SPHI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEI91544.1};	33.02	215	138	6	466	676	71	283	7e-20	101
rs:WP_044475278	DNA topoisomerase I [Streptococcus suis].	23.22	577	375	18	83	629	72	610	7e-20	104
rs:WP_018757832	DNA topoisomerase I [Paenibacillus terrigena].	24.91	574	353	22	103	635	80	616	7e-20	104
rs:WP_020493125	DNA topoisomerase I [Dehalobacter sp. FTH1].	23.93	702	437	29	3	671	5	642	7e-20	104
rs:WP_047090521	DNA topoisomerase III, partial [Escherichia coli].	30.66	274	169	7	421	676	1	271	7e-20	100
rs:WP_022415147	DNA topoisomerase [Dorea longicatena CAG:42].	23.84	558	360	19	90	616	67	590	7e-20	104
rs:WP_018922566	DNA topoisomerase I [Salsuginibacillus kocurii].	25.10	514	327	20	153	635	127	613	7e-20	104
rs:WP_008637892	MULTISPECIES: DNA topoisomerase I [Bacillaceae].	26.11	517	309	22	157	635	132	613	7e-20	104
rs:WP_036848572	DNA topoisomerase I, partial [Porphyromonas sp. COT-108 OH1349].	33.64	214	130	8	466	676	78	282	7e-20	101
rs:WP_047207279	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	7e-20	104
rs:WP_011630365	DNA topoisomerase I [Alkalilimnicola ehrlichii].	23.33	673	394	24	3	610	5	620	7e-20	104
rs:WP_003541173	DNA topoisomerase I [Desulfotomaculum nigrificans].	25.70	568	341	21	89	616	68	594	7e-20	104
rs:WP_024048967	DNA topoisomerase [Negativicoccus succinicivorans].	23.51	706	429	23	3	671	37	668	7e-20	104
rs:WP_015829234	DNA topoisomerase I [Methylovorus glucosotrophus].	23.56	675	409	26	2	630	3	616	7e-20	105
rs:XP_011462844	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Fragaria vesca subsp. vesca].	22.99	609	401	19	54	631	6	577	7e-20	104
rs:XP_002153907	PREDICTED: DNA topoisomerase 3-beta-1-like [Hydra vulgaris].	24.25	569	362	21	3	537	5	538	7e-20	104
rs:WP_046407983	DNA topoisomerase I [Sphingomonas sp. Ag1].	22.35	671	422	21	1	629	1	614	7e-20	105
rs:WP_046272835	DNA topoisomerase I [Stenotrophomonas maltophilia].	24.61	581	335	21	3	538	5	527	7e-20	104
rs:WP_036826674	DNA topoisomerase I [Polaribacter sp. Hel1_85].	25.89	533	321	19	3	521	5	477	7e-20	104
tr:Q9HS90_HALSA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.60	514	329	15	188	661	22	501	7e-20	104
tr:E4Y9S6_OIKDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.84	604	377	21	3	564	5	567	7e-20	104
rs:WP_020997791	DNA topoisomerase I [Streptococcus constellatus].	24.17	575	371	21	83	629	70	607	7e-20	104
tr:A0A0E0W3G8_BACAN	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:AFH85168.1};	24.24	561	366	21	105	635	41	572	7e-20	104
rs:WP_031607064	DNA topoisomerase III, partial [Salmonella enterica].	29.79	235	143	6	1	224	1	224	7e-20	99.8
rs:WP_044545985	DNA topoisomerase I, partial [Parabacteroides distasonis].	33.33	222	136	8	466	684	37	249	7e-20	100
rs:WP_015044145	MULTISPECIES: DNA topoisomerase I [Dehalobacter].	23.79	702	438	28	3	671	5	642	8e-20	104
rs:WP_012506744	DNA topoisomerase I [Prosthecochloris aestuarii].	25.29	609	356	23	76	629	63	627	8e-20	104
rs:WP_022483769	DNA topoisomerase [Clostridium sp. CAG:389].	23.80	542	348	15	103	614	80	586	8e-20	104
rs:WP_033794941	DNA topoisomerase I, partial [Bacillus sp. 105MF].	30.94	278	173	10	3	268	5	275	8e-20	100
rs:WP_023061818	DNA topoisomerase [Lactobacillus helveticus].	24.87	571	350	21	103	635	93	622	8e-20	104
rs:WP_002815553	hypothetical protein, partial [Campylobacter coli].	24.29	527	342	15	81	579	55	552	8e-20	103
rs:WP_026590316	DNA topoisomerase I [Bacillus sp. UNC437CL72CviS29].	24.20	562	369	21	103	635	80	613	8e-20	104
rs:WP_046169030	DNA topoisomerase I [Devosia psychrophila].	22.51	684	415	22	1	629	1	624	8e-20	104
rs:WP_003626499	DNA topoisomerase I [Lactobacillus helveticus].	24.87	571	350	21	103	635	93	622	8e-20	104
rs:WP_025283551	DNA topoisomerase I [Lactobacillus helveticus].	24.87	571	350	21	103	635	93	622	8e-20	104
tr:I6F9D3_SHIBO	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EIQ52875.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EIQ52875.1};	28.22	241	156	8	65	290	1	239	8e-20	100
rs:WP_013537158	DNA topoisomerase I [Thermovibrio ammonificans].	23.35	681	390	27	2	630	4	604	8e-20	104
rs:WP_026494468	DNA topoisomerase I [Butyrivibrio sp. WCD3002].	24.16	563	352	17	90	616	70	593	8e-20	104
rs:WP_045355889	DNA topoisomerase I [Enterobacter asburiae].	23.75	602	366	23	76	633	82	634	8e-20	104
rs:WP_041639327	DNA topoisomerase III, partial [Anoxybacillus flavithermus].	27.72	303	181	8	349	646	36	305	8e-20	102
rs:WP_041981298	DNA topoisomerase I [Streptococcus agalactiae].	24.51	559	352	22	103	630	99	618	8e-20	104
rs:WP_034172188	DNA topoisomerase I [Chrysanthemum yellows phytoplasma].	26.36	516	319	16	88	581	65	541	8e-20	104
rs:WP_046736113	DNA topoisomerase III, partial [Xanthomonas axonopodis].	30.30	231	144	7	1	222	1	223	8e-20	100
rs:WP_020409425	topoisomerase I [Hahella ganghwensis].	23.97	634	400	20	76	673	93	680	8e-20	104
rs:WP_016316209	DNA topoisomerase I [Anaerotruncus sp. G3(2012)].	23.71	620	397	22	97	679	77	657	8e-20	104
tr:U7SXU1_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.81	620	367	23	2	589	9	567	8e-20	105
rs:WP_020803119	toprim domain protein, partial [Klebsiella pneumoniae].	29.39	296	180	10	1	276	1	287	8e-20	100
tr:A0A098EKZ4_9BACL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.35	564	345	21	103	629	80	604	8e-20	104
rs:WP_013810225	DNA topoisomerase I [Desulfotomaculum carboxydivorans].	25.70	568	341	21	89	616	68	594	8e-20	104
rs:WP_014998125	topoisomerase I [Alteromonas macleodii].	25.77	617	353	26	65	629	75	638	8e-20	104
rs:WP_006567147	MULTISPECIES: DNA topoisomerase I [Anaerostipes].	23.40	658	386	24	3	616	5	588	8e-20	104
rs:WP_031434896	DNA topoisomerase I [Methylomarinum vadi].	23.15	717	445	28	3	673	5	661	8e-20	104
tr:A0A0B7NMC0_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.95	501	316	15	163	631	178	645	8e-20	105
rs:XP_011402446	PREDICTED: DNA topoisomerase 3-beta-1-like, partial [Amphimedon queenslandica].	24.17	451	280	14	163	586	177	592	8e-20	104
rs:WP_026861812	DNA topoisomerase I [Idiomarina sediminum].	23.96	647	402	22	76	680	88	686	8e-20	104
rs:WP_002287487	DNA topoisomerase I [Streptococcus mutans].	24.31	580	367	22	83	630	78	617	8e-20	104
rs:WP_035137691	DNA topoisomerase [Collinsella sp. 4_8_47FAA].	24.79	601	354	26	58	616	109	653	8e-20	104
rs:WP_045360425	DNA topoisomerase I [Enterobacter aerogenes].	23.59	619	366	22	60	633	78	634	8e-20	104
rs:WP_046781988	DNA topoisomerase I [Lactococcus lactis].	25.00	556	351	20	103	629	99	617	8e-20	104
rs:WP_031552739	DNA topoisomerase I [Parvularcula oceani].	25.31	573	333	23	1	534	1	517	8e-20	104
rs:WP_036610755	DNA topoisomerase I [Oribacterium sp. P6A1].	23.31	635	410	21	3	616	5	583	8e-20	104
rs:WP_014070501	topoisomerase I [Enterobacter asburiae].	23.83	600	368	20	76	633	82	634	8e-20	104
rs:WP_022299282	DNA topoisomerase [Clostridium sp. CAG:964].	23.32	656	394	24	2	616	3	590	8e-20	104
rs:WP_021916891	DNA topoisomerase [Brachyspira sp. CAG:484].	24.38	681	395	25	3	636	27	634	8e-20	104
tr:G0EL64_BRAIP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.89	632	395	22	36	629	15	598	8e-20	104
rs:WP_017437098	DNA topoisomerase I [Geobacillus caldoxylosilyticus].	24.56	509	327	18	157	635	132	613	8e-20	104
rs:WP_033646015	DNA topoisomerase I [Bacillus anthracis].	24.06	561	367	21	105	635	82	613	8e-20	104
rs:WP_001961705	DNA topoisomerase I [Vibrio cholerae].	24.13	605	363	22	75	633	87	641	8e-20	104
rs:WP_033481886	MULTISPECIES: DNA topoisomerase III, partial [Xanthomonas].	29.65	226	144	6	1	219	1	218	8e-20	99.8
tr:A0A074LLS2_9BACL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.58	655	386	24	3	615	5	593	8e-20	104
rs:WP_044832579	DNA topoisomerase I [Thalassomonas actiniarum].	25.62	609	366	24	65	631	75	638	8e-20	104
rs:WP_022191330	DNA topoisomerase [Firmicutes bacterium CAG:240].	23.32	656	392	23	3	616	8	594	8e-20	104
rs:WP_045908888	DNA topoisomerase I [Enterobacter cloacae].	24.00	600	367	21	76	633	82	634	8e-20	104
rs:XP_008500955	PREDICTED: DNA topoisomerase 3-beta-1 [Calypte anna].	22.95	610	383	20	3	564	5	575	8e-20	104
rs:WP_046836243	DNA topoisomerase I [Staphylococcus succinus].	24.68	551	363	19	103	629	80	602	9e-20	104
tr:E6Q8V3_9ZZZZ	SubName: Full=DNA topoisomerase I, plasmid (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) {ECO:0000313|EMBL:CBI03629.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI03629.1};	24.56	570	334	19	1	537	1	507	9e-20	104
rs:WP_002278553	DNA topoisomerase I [Streptococcus mutans].	24.57	582	363	24	83	630	78	617	9e-20	104
rs:WP_013244953	DNA topoisomerase I [Brachyspira pilosicoli].	23.94	660	410	23	3	629	15	615	9e-20	104
rs:WP_032884070	DNA topoisomerase I [Fusobacterium nucleatum].	25.69	619	369	22	2	589	12	570	9e-20	104
rs:WP_037543181	DNA topoisomerase I [Staphylococcus pseudintermedius].	24.39	570	368	21	90	629	67	603	9e-20	104
rs:XP_005107460	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X1 [Aplysia californica].	22.77	606	399	19	3	572	5	577	9e-20	104
tr:U7SSI8_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.16	616	376	21	2	589	9	567	9e-20	104
rs:WP_021037269	DNA topoisomerase I TopA [Lactococcus lactis].	25.00	556	351	20	103	629	99	617	9e-20	104
rs:WP_012959400	DNA topoisomerase I [Bacillus pseudofirmus].	24.19	554	367	19	103	630	80	606	9e-20	104
rs:WP_018917300	topoisomerase I [Halomonas zhanjiangensis].	25.34	596	360	19	76	633	94	642	9e-20	104
rs:WP_043029703	DNA topoisomerase I [Streptococcus equi].	24.18	579	369	22	83	630	84	623	9e-20	104
rs:WP_040955680	DNA topoisomerase I [Virgibacillus sp. SK37].	25.18	568	357	22	103	635	80	614	9e-20	104
rs:WP_009423475	DNA topoisomerase I [Fusobacterium sp. oral taxon 370].	25.49	616	374	20	2	589	12	570	9e-20	104
rs:WP_022458468	DNA topoisomerase [Fusobacterium sp. CAG:439].	23.15	691	388	21	3	631	22	631	9e-20	104
rs:WP_046814120	DNA topoisomerase I [Lactobacillus helveticus].	24.87	571	350	21	103	635	93	622	9e-20	104
rs:XP_005515230	PREDICTED: DNA topoisomerase 3-beta-1 [Columba livia].	22.73	607	388	19	3	564	5	575	9e-20	104
rs:WP_042748214	DNA topoisomerase I [Lactococcus lactis].	25.00	556	351	20	103	629	101	619	9e-20	104
rs:WP_000520426	topoisomerase I [Vibrio cholerae].	24.13	605	363	22	75	633	87	641	9e-20	104
rs:WP_002489763	DNA topoisomerase I [Staphylococcus epidermidis].	23.48	558	368	16	100	629	77	603	9e-20	104
rs:WP_039847570	DNA topoisomerase III, partial [Pseudomonas amygdali].	27.24	290	193	6	350	629	1	282	9e-20	100
rs:WP_047021469	hypothetical protein [Lactobacillus brevis].	24.07	619	411	23	44	632	45	634	9e-20	104
rs:WP_010863937	DNA topoisomerase I subunit omega [Plesiomonas shigelloides].	23.99	646	405	19	74	680	87	685	9e-20	104
rs:WP_002264284	DNA topoisomerase I [Streptococcus mutans].	24.31	580	367	22	83	630	78	617	9e-20	104
tr:T4BJJ7_PEPDI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	23.72	607	375	25	65	631	111	669	9e-20	104
rs:WP_043904103	DNA topoisomerase I [Geobacillus stearothermophilus].	24.75	509	326	19	157	635	132	613	9e-20	104
rs:WP_022430440	DNA topoisomerase III [Prevotella stercorea CAG:629].	27.43	339	220	13	355	678	5	332	9e-20	101
rs:WP_038059400	hypothetical protein, partial [Thermodesulfovibrio islandicus].	26.72	595	341	22	89	629	66	619	9e-20	104
tr:A0A017RZG0_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	25.57	442	279	13	200	618	1	415	9e-20	103
rs:WP_024563609	DNA topoisomerase I [Wheat blue dwarf phytoplasma].	24.91	570	357	18	86	629	63	587	9e-20	103
rs:XP_010130050	PREDICTED: DNA topoisomerase 3-beta-1 [Buceros rhinoceros silvestris].	22.90	607	387	19	3	564	5	575	9e-20	104
rs:WP_024907119	DNA topoisomerase I [Enterobacter asburiae].	23.83	600	368	21	76	633	82	634	9e-20	104
tr:C3F5U4_BACTU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.24	561	366	21	105	635	75	606	9e-20	104
rs:WP_027836252	DNA topoisomerase I [Mastigocoleus testarum].	24.30	683	406	32	1	629	1	626	9e-20	104
rs:WP_014979097	topoisomerase I [Alteromonas macleodii].	25.77	617	353	26	65	629	75	638	9e-20	104
rs:WP_044261256	DNA topoisomerase I, partial [Candidatus Prevotella conceptionensis].	34.60	211	121	7	34	230	1	208	1e-19	99.0
rs:WP_020882439	MULTISPECIES: DNA topoisomerase I [Enterobacter cloacae complex].	23.72	607	360	21	76	633	82	634	1e-19	104
rs:WP_022105370	DNA topoisomerase [Dialister sp. CAG:486].	25.08	590	348	23	88	629	90	633	1e-19	104
rs:WP_033924726	DNA topoisomerase I [Sphingomonas sp. 35-24ZXX].	23.24	667	421	22	1	629	1	614	1e-19	104
tr:F3GEZ0_PSESJ	SubName: Full=Orf50 {ECO:0000313|EMBL:EGH45640.1}; Flags: Fragment;	27.33	344	207	13	1	317	1	328	1e-19	101
rs:WP_022216093	DNA topoisomerase [Coprococcus sp. CAG:131].	25.04	655	379	27	3	616	30	613	1e-19	104
rs:WP_029439593	DNA topoisomerase I [Bacillus thuringiensis].	23.93	560	369	20	105	635	82	613	1e-19	103
rs:WP_044623863	DNA topoisomerase I [Photobacterium gaetbulicola].	24.37	591	375	18	76	633	88	639	1e-19	104
rs:WP_023312071	DNA topoisomerase 1 [Enterobacter cloacae].	23.75	602	366	23	76	633	82	634	1e-19	104
rs:WP_006182012	DNA topoisomerase I [Natrinema pellirubrum].	21.68	738	447	25	1	661	1	684	1e-19	104
rs:WP_000246612	DNA topoisomerase I [Streptococcus agalactiae].	24.06	561	352	19	103	630	99	618	1e-19	104
rs:WP_023350396	MULTISPECIES: DNA topoisomerase I [Staphylococcus].	24.46	556	359	20	103	629	80	603	1e-19	103
rs:WP_029674661	DNA topoisomerase I [Butyrivibrio sp. VCB2006].	25.31	557	353	19	90	616	62	585	1e-19	103
rs:WP_006527281	DNA topoisomerase I [Gloeocapsa sp. PCC 73106].	24.12	597	364	17	90	637	72	628	1e-19	104
rs:WP_045620487	DNA topoisomerase I [Enterobacter cloacae].	23.75	602	366	23	76	633	82	634	1e-19	104
rs:WP_014572601	DNA topoisomerase I [Lactococcus lactis].	25.00	556	351	20	103	629	101	619	1e-19	103
rs:WP_039468103	DNA topoisomerase I [Photobacterium gaetbulicola].	24.37	591	375	18	76	633	88	639	1e-19	104
rs:WP_025820579	DNA topoisomerase I [Shewanella marina].	23.87	595	375	21	74	631	88	641	1e-19	104
tr:G8LDT2_ENTCL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.72	607	360	21	76	633	84	636	1e-19	104
rs:WP_021211410	DNA topoisomerase I [Lactococcus lactis].	25.00	556	351	20	103	629	103	621	1e-19	103
rs:WP_027363825	DNA topoisomerase I [Desulfotomaculum alcoholivorax].	23.41	581	376	20	88	629	62	612	1e-19	104
rs:WP_004816257	DNA topoisomerase I [Anaerococcus hydrogenalis].	25.50	647	370	26	3	611	5	577	1e-19	103
rs:WP_043030795	DNA topoisomerase I [Streptococcus equi].	24.18	579	369	22	83	630	84	623	1e-19	103
rs:XP_005524443	PREDICTED: DNA topoisomerase 3-beta-1 [Pseudopodoces humilis].	22.90	607	387	19	3	564	5	575	1e-19	104
rs:XP_006269379	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Alligator mississippiensis].	22.73	607	388	18	3	564	5	575	1e-19	104
rs:WP_026775681	DNA topoisomerase I [Polaribacter sp. Hel_I_88].	25.61	535	320	18	3	521	5	477	1e-19	104
rs:WP_039217423	DNA topoisomerase III, partial [Clostridium novyi].	35.43	175	100	6	3	172	5	171	1e-19	98.2
rs:WP_007438736	DNA topoisomerase I [Acetobacteraceae bacterium AT-5844].	24.18	641	386	25	55	630	28	633	1e-19	104
rs:WP_012698584	DNA topoisomerase I [Laribacter hongkongensis].	23.66	672	409	21	3	630	5	616	1e-19	104
rs:WP_000520425	topoisomerase I [Vibrio cholerae].	24.13	605	363	22	75	633	87	641	1e-19	104
rs:WP_015409059	DNA topoisomerase I [Natronomonas moolapensis].	23.56	675	389	31	1	616	1	607	1e-19	104
rs:WP_045400177	DNA topoisomerase I [Enterobacter asburiae].	23.75	602	366	23	76	633	82	634	1e-19	104
rs:WP_040286872	DNA topoisomerase I [Sporosarcina koreensis].	23.30	558	374	14	100	630	77	607	1e-19	103
rs:WP_022435372	DNA topoisomerase [Firmicutes bacterium CAG:321].	24.29	667	392	26	2	629	4	596	1e-19	103
rs:WP_013489103	DNA topoisomerase I [Bacillus cellulosilyticus].	24.19	558	362	18	103	630	80	606	1e-19	103
rs:WP_041154867	DNA topoisomerase I [Vibrio mytili].	24.20	591	380	17	75	633	86	640	1e-19	104
rs:WP_032824990	topoisomerase I, partial [Oenococcus oeni].	34.63	205	124	6	3	198	4	207	1e-19	99.0
rs:WP_016682821	DNA topoisomerase III, partial [Yersinia pestis].	26.11	337	226	8	77	391	18	353	1e-19	102
rs:WP_027727258	DNA topoisomerase I [Treponema sp. C6A8].	23.84	583	371	19	83	630	69	613	1e-19	103
rs:WP_044720923	hypothetical protein [Streptococcus suis].	35.52	183	100	6	3	174	4	179	1e-19	98.2
tr:W4RS51_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE46703.1};	28.43	306	181	8	349	647	30	304	1e-19	101
rs:WP_000520427	topoisomerase I [Vibrio cholerae].	24.13	605	363	22	75	633	87	641	1e-19	104
rs:WP_022114217	DNA topoisomerase [Clostridium sp. CAG:245].	24.01	479	295	16	187	629	21	466	1e-19	103
rs:XP_003704123	PREDICTED: DNA topoisomerase 3-beta-1 [Megachile rotundata].	21.42	677	447	20	3	630	5	645	1e-19	104
tr:A0A064C8N5_9STAP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.46	556	359	20	103	629	82	605	1e-19	103
rs:WP_043053080	DNA topoisomerase I [Streptococcus equi].	24.18	579	369	21	83	630	84	623	1e-19	103
rs:WP_022184182	DNA topoisomerase type IA central domain protein [Eggerthella sp. CAG:209].	24.23	549	359	20	90	616	135	648	1e-19	104
rs:WP_007719372	DNA topoisomerase I [Brevibacillus sp. BC25].	24.51	563	368	22	103	636	80	614	1e-19	103
rs:WP_027623453	DNA topoisomerase I [Clostridium lundense].	24.27	651	391	22	2	616	4	588	1e-19	103
rs:WP_009052420	DNA topoisomerase I [Thermoanaerobacter sp. X561].	24.62	585	352	20	90	629	67	607	1e-19	103
tr:I2WFJ6_ECOLX	SubName: Full=Topoisomerase DNA-binding C4 zinc finger domain protein {ECO:0000313|EMBL:EII23424.1};	24.09	357	215	10	374	677	1	354	1e-19	101
rs:XP_009995964	PREDICTED: DNA topoisomerase 3-beta-1 [Chaetura pelagica].	22.57	607	389	19	3	564	5	575	1e-19	104
rs:WP_008174370	MULTISPECIES: topoisomerase I [Marinobacter].	24.29	597	380	20	72	633	86	645	1e-19	104
rs:WP_047166403	DNA topoisomerase I [Sphingomonas sp. Y57].	21.76	717	462	21	1	675	1	660	1e-19	104
rs:WP_041455453	DNA topoisomerase I [Anaerolinea thermophila].	23.26	602	379	20	76	630	49	614	1e-19	103
rs:WP_034434629	DNA topoisomerase I [Clostridiales bacterium S5-A14a].	25.93	563	334	19	90	616	75	590	1e-19	103
rs:WP_015891767	DNA topoisomerase I [Brevibacillus brevis].	24.87	563	364	22	103	635	80	613	1e-19	103
rs:WP_027307457	DNA topoisomerase I [Caloramator sp. ALD01].	24.05	578	374	17	83	629	60	603	1e-19	103
rs:WP_007060088	DNA topoisomerase I [Clostridium carboxidivorans].	25.04	651	386	23	2	616	4	588	1e-19	103
rs:WP_047151637	DNA topoisomerase I [Aneurinibacillus tyrosinisolvens].	24.00	575	375	20	88	630	62	606	1e-19	103
rs:XP_009279077	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Aptenodytes forsteri].	22.90	607	387	19	3	564	5	575	1e-19	104
tr:I8R0U8_9THEO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952}; Flags: Precursor;	24.27	585	354	20	90	629	67	607	1e-19	103
rs:WP_015366223	DNA topoisomerase I [Enterobacter aerogenes].	23.59	619	366	22	60	633	78	634	1e-19	104
rs:WP_011947523	DNA topoisomerase I [Legionella pneumophila].	25.94	636	389	29	55	641	29	631	1e-19	103
rs:WP_023007343	topoisomerase I [Halomonas sp. PBN3].	26.00	477	290	18	186	633	201	643	1e-19	104
rs:WP_022378022	GTP-sensing transcriptional pleiotropic repressor CodY [Clostridium sp. CAG:62].	23.08	559	360	19	90	616	67	587	1e-19	103
rs:XP_010414049	PREDICTED: DNA topoisomerase 3-beta-like isoform X2 [Camelina sativa].	24.85	507	322	18	105	586	76	548	1e-19	103
rs:WP_018282125	hypothetical protein [zeta proteobacterium SCGC AB-137-C09].	24.33	485	315	13	77	533	53	513	1e-19	103
rs:WP_002564088	MULTISPECIES: DNA topoisomerase I [Atopobium].	24.04	570	365	20	78	620	126	654	1e-19	104
tr:A0A0D0I5I6_BACTM	SubName: Full=Bacillus thuringiensis serovar morrisoni strain HD 600 BG10.Contig244, whole genome shotgun sequence {ECO:0000313|EMBL:KIP25088.1};	39.64	169	91	5	465	627	8	171	1e-19	100
rs:WP_046124918	DNA topoisomerase I [Lactococcus lactis].	25.00	556	351	20	103	629	101	619	1e-19	103
rs:XP_012214509	PREDICTED: DNA topoisomerase 3-beta-1 [Linepithema humile].	21.80	679	442	22	3	630	5	645	1e-19	104
rs:WP_032611192	DNA topoisomerase I [Leclercia adecarboxylata].	25.04	599	370	23	73	633	76	633	1e-19	104
rs:WP_045041611	DNA topoisomerase I [Photobacterium kishitanii].	24.50	596	376	23	73	633	83	639	1e-19	104
rs:WP_031572738	DNA topoisomerase I [Proteiniclasticum ruminis].	26.00	577	350	21	90	629	67	603	1e-19	103
rs:WP_022481595	DNA topoisomerase [Clostridium sp. CAG:729].	23.00	700	408	23	3	646	22	646	1e-19	103
rs:WP_010691753	DNA topoisomerase I [Fructobacillus fructosus].	23.90	661	408	22	2	629	27	625	1e-19	103
rs:WP_003869178	DNA topoisomerase I [Thermoanaerobacter ethanolicus].	24.27	585	354	20	90	629	67	607	1e-19	103
rs:WP_023845950	DNA topoisomerase I, archaeal [Methanolobus tindarius].	23.28	670	425	30	1	629	1	622	1e-19	103
rs:WP_014844720	DNA topoisomerase I [Legionella pneumophila].	25.94	636	389	29	55	641	29	631	1e-19	103
rs:WP_015311654	DNA topoisomerase I [Thermoanaerobacterium thermosaccharolyticum].	26.09	621	368	24	90	669	67	637	1e-19	103
rs:WP_028762074	DNA topoisomerase I [Shewanella colwelliana].	24.01	608	362	21	74	633	88	643	1e-19	104
rs:WP_042068216	DNA topoisomerase I ['Chrysanthemum coronarium' phytoplasma].	25.53	568	352	19	88	629	65	587	1e-19	103
rs:WP_028372589	DNA topoisomerase I [Legionella lansingensis].	25.43	645	380	31	55	641	29	630	1e-19	103
rs:WP_036795343	DNA topoisomerase I [Photobacterium phosphoreum].	24.50	596	376	23	73	633	83	639	1e-19	103
rs:WP_021354089	hypothetical protein, partial [Corynebacterium pseudodiphtheriticum].	36.13	191	113	6	41	223	1	190	1e-19	99.4
rs:WP_021035179	DNA topoisomerase I [Haemophilus influenzae].	25.05	475	298	14	187	633	196	640	1e-19	103
rs:WP_039044872	DNA topoisomerase I [Plesiomonas shigelloides].	23.99	646	405	19	74	680	87	685	1e-19	103
rs:WP_028767265	DNA topoisomerase I [Shewanella fidelis].	23.80	605	368	21	74	633	88	644	1e-19	103
rs:WP_022969384	DNA topoisomerase I [Arenimonas oryziterrae].	23.48	528	330	14	55	538	29	526	1e-19	103
tr:G2TJM1_BACCO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.28	519	321	21	154	635	1	484	1e-19	103
rs:WP_023023206	DNA topoisomerase I [Streptococcus sp. I-P16].	23.18	578	373	18	83	629	71	608	1e-19	103
rs:WP_013533917	DNA topoisomerase I [Pseudoxanthomonas suwonensis].	25.71	490	303	16	85	538	62	526	1e-19	103
rs:WP_041691324	hypothetical protein, partial [Elusimicrobium minutum].	26.24	625	364	25	79	643	49	636	1e-19	103
rs:WP_022389687	DNA topoisomerase [Tannerella sp. CAG:51].	24.23	553	356	16	77	612	54	560	1e-19	103
rs:WP_002436312	DNA topoisomerase I [Staphylococcus capitis].	24.46	556	359	20	103	629	80	603	1e-19	103
rs:WP_027634208	DNA topoisomerase I [Clostridium hydrogeniformans].	26.46	616	341	23	90	630	67	645	1e-19	103
rs:WP_019321618	DNA topoisomerase I [Streptococcus mutans].	23.71	582	368	22	83	630	78	617	1e-19	103
rs:WP_008329900	DNA topoisomerase I [Maritimibacter alkaliphilus].	23.50	685	409	27	1	629	1	626	1e-19	103
rs:WP_022519081	DNA topoisomerase [Roseburia sp. CAG:100].	24.32	625	379	20	90	671	67	640	1e-19	103
rs:WP_033694419	hypothetical protein [Bacillus thuringiensis].	26.47	340	217	9	351	676	1	321	1e-19	100
rs:WP_032688111	MULTISPECIES: DNA topoisomerase I [Raoultella].	23.79	597	383	19	73	633	74	634	1e-19	103
rs:XP_010202476	PREDICTED: DNA topoisomerase 3-beta-1 [Colius striatus].	22.73	607	388	19	3	564	5	575	1e-19	103
rs:XP_009414691	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Musa acuminata subsp. malaccensis].	22.81	627	395	25	3	586	6	586	1e-19	103
rs:WP_001286958	DNA topoisomerase I [Bacillus cereus].	23.75	560	370	20	105	635	82	613	1e-19	103
rs:WP_026675886	DNA topoisomerase I [Fictibacillus gelatini].	24.91	566	363	19	103	636	80	615	1e-19	103
rs:WP_013881179	DNA topoisomerase I [Halopiger xanaduensis].	22.19	694	434	29	1	642	1	640	1e-19	103
rs:WP_046003777	DNA topoisomerase I [Pseudoalteromonas rubra].	24.49	592	381	19	72	631	84	641	1e-19	103
rs:WP_002453083	DNA topoisomerase I [Staphylococcus capitis].	24.46	556	359	19	103	629	80	603	1e-19	103
rs:WP_017355382	DNA topoisomerase I [Stenotrophomonas maltophilia].	23.80	689	410	25	3	638	5	631	1e-19	103
rs:XP_009816881	PREDICTED: DNA topoisomerase 3-beta-1 [Gavia stellata].	22.90	607	387	19	3	564	5	575	1e-19	103
rs:WP_015705739	topoisomerase I [Enterobacter aerogenes].	23.59	619	366	22	60	633	78	634	1e-19	103
rs:WP_027434871	DNA topoisomerase I [Lachnospiraceae bacterium AB2028].	24.24	561	365	19	87	616	64	595	1e-19	103
rs:WP_023894191	hypothetical protein, partial [Salmonella enterica].	30.43	230	138	6	1	219	1	219	1e-19	99.0
rs:WP_005928228	DNA topoisomerase I [Faecalibacterium prausnitzii].	24.83	580	375	19	83	630	59	609	1e-19	103
rs:WP_043318076	DNA topoisomerase I [Microbulbifer sp. HZ11].	23.09	641	424	19	65	673	80	683	1e-19	103
rs:WP_034790972	DNA topoisomerase I [Ewingella americana].	23.74	653	382	26	76	673	82	673	1e-19	103
rs:WP_013120419	DNA topoisomerase I [Thermincola potens].	23.72	565	353	16	90	616	67	591	1e-19	103
rs:WP_011784655	MULTISPECIES: topoisomerase I [Marinobacter].	23.74	594	375	16	76	633	93	644	1e-19	103
rs:WP_042853351	DNA topoisomerase III, partial [Staphylococcus aureus].	34.45	209	116	8	3	196	4	206	1e-19	98.6
rs:WP_046163817	DNA topoisomerase I [Pseudomonas sp. 10B238].	23.62	597	375	16	74	633	84	636	1e-19	103
rs:XP_009976028	PREDICTED: DNA topoisomerase 3-beta-1 [Tauraco erythrolophus].	22.90	607	387	19	3	564	5	575	1e-19	103
rs:WP_025756584	MULTISPECIES: DNA topoisomerase I [Enterobacter].	24.00	600	367	21	76	633	82	634	1e-19	103
rs:WP_024267208	DNA topoisomerase I [Salinispira pacifica].	24.96	593	335	21	3	538	7	546	1e-19	103
rs:WP_005213329	DNA topoisomerase I [Clostridium celatum].	25.17	600	343	20	103	630	80	645	1e-19	103
rs:WP_032647574	MULTISPECIES: DNA topoisomerase I [Enterobacter].	23.83	600	368	21	76	633	82	634	1e-19	103
rs:WP_038067626	DNA topoisomerase I [Thioclava dalianensis].	23.20	694	432	23	1	630	1	657	1e-19	103
rs:WP_038289556	DNA topoisomerase I [Zooshikella ganghwensis].	25.00	608	353	21	74	633	91	643	1e-19	103
rs:WP_002498363	DNA topoisomerase I [Staphylococcus epidermidis].	24.15	559	363	18	100	629	77	603	1e-19	103
rs:WP_011927903	DNA topoisomerase I [Dichelobacter nodosus].	23.99	567	336	21	3	534	6	512	2e-19	103
rs:WP_035945202	DNA topoisomerase I [Fusobacterium perfoetens].	24.77	650	387	24	3	620	9	588	2e-19	103
rs:WP_015423678	DNA topoisomerase I [uncultured Termite group 1 bacterium].	24.53	689	396	27	3	640	5	620	2e-19	103
rs:WP_040099963	DNA topoisomerase I, partial [Geoalkalibacter ferrihydriticus].	23.40	705	421	27	3	649	5	648	2e-19	103
rs:WP_038415193	DNA topoisomerase I [Bacillus thuringiensis].	23.75	560	370	20	105	635	82	613	2e-19	103
tr:W5FIW1_WHEAT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.40	625	403	25	31	614	14	597	2e-19	103
tr:D4K7I0_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.83	580	375	19	83	630	59	609	2e-19	103
rs:WP_011878312	DNA topoisomerase I [Desulfotomaculum reducens].	25.05	555	336	22	100	616	77	589	2e-19	103
tr:A0A0C7E5F3_XANCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.43	573	345	20	3	538	5	526	2e-19	103
rs:WP_042097930	DNA topoisomerase III, partial [Escherichia coli].	28.09	299	180	10	1	276	1	287	2e-19	100
rs:XP_009886431	PREDICTED: DNA topoisomerase 3-beta-1 [Charadrius vociferus].	22.90	607	387	19	3	564	5	575	2e-19	103
rs:WP_047071578	DNA topoisomerase I [Enterobacter asburiae].	24.00	600	367	22	76	633	82	634	2e-19	103
rs:WP_039464588	DNA topoisomerase I [Vibrio navarrensis].	24.06	611	376	21	57	633	83	639	2e-19	103
rs:WP_014949190	topoisomerase I [Alteromonas macleodii].	24.88	615	361	24	65	629	75	638	2e-19	103
rs:WP_044746154	DNA topoisomerase I [Anoxybacillus sp. ATCC BAA-2555].	24.25	503	326	16	156	630	131	606	2e-19	103
rs:WP_011722224	MULTISPECIES: DNA topoisomerase I [Clostridium].	24.39	701	399	22	2	630	4	645	2e-19	103
rs:WP_040396702	DNA topoisomerase I [Anaerococcus senegalensis].	25.08	650	369	25	3	611	5	577	2e-19	103
tr:D5TVA4_BACT1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.75	560	370	20	105	635	41	572	2e-19	103
rs:XP_002404156	topoisomerase I, putative [Ixodes scapularis].	22.44	606	389	19	3	564	5	573	2e-19	103
rs:WP_014294544	DNA topoisomerase I [Streptococcus macedonicus].	22.99	561	358	20	103	630	106	625	2e-19	103
rs:WP_039457938	DNA topoisomerase I [Thermus sp. 2.9].	24.49	584	344	17	77	616	69	599	2e-19	103
rs:WP_034629666	DNA topoisomerase I [Bacillus okhensis].	24.01	554	369	18	103	630	80	607	2e-19	103
rs:WP_006269520	DNA topoisomerase I [Streptococcus constellatus].	24.00	575	372	21	83	629	70	607	2e-19	103
rs:WP_041503327	MULTISPECIES: DNA topoisomerase I [unclassified Porphyromonadaceae].	25.92	544	310	17	3	520	5	481	2e-19	103
rs:WP_035328942	DNA topoisomerase I [Bacillus firmus].	23.71	561	371	19	105	636	82	614	2e-19	103
rs:WP_046104204	DNA topoisomerase I [Devosia chinhatensis].	22.98	692	402	24	1	629	1	624	2e-19	103
rs:WP_016121776	DNA topoisomerase 3, partial [Bacillus cereus].	39.64	169	91	5	465	627	62	225	2e-19	100
rs:XP_009581659	PREDICTED: DNA topoisomerase 3-beta-1 [Fulmarus glacialis].	22.90	607	387	19	3	564	5	575	2e-19	103
rs:WP_022423366	DNA topoisomerase [Clostridium sp. CAG:440].	24.70	575	362	23	90	629	67	605	2e-19	103
tr:W7ZTL7_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAF20066.1};	26.48	355	239	10	349	683	16	368	2e-19	100
tr:A0A0D6E964_9GAMM	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:CEP35824.1};	25.42	598	357	20	76	633	94	642	2e-19	103
rs:WP_006729968	DNA topoisomerase I [Lactobacillus iners].	25.27	562	346	20	103	629	85	607	2e-19	103
rs:WP_019802704	DNA topoisomerase I [Streptococcus mutans].	23.67	583	367	23	83	630	78	617	2e-19	103
rs:WP_028454731	DNA topoisomerase I [Chitinilyticum litopenaei].	23.87	599	379	19	74	630	51	614	2e-19	103
rs:WP_006743812	DNA topoisomerase I [Bacteroides coprosuis].	26.02	561	339	20	77	613	54	562	2e-19	103
rs:WP_016532567	DNA topoisomerase III, partial [Klebsiella pneumoniae].	33.70	184	109	6	1	177	1	178	2e-19	97.8
rs:WP_022141914	DNA topoisomerase [Clostridium sp. CAG:230].	24.73	562	348	20	90	616	67	588	2e-19	103
rs:WP_006735030	MULTISPECIES: DNA topoisomerase I [Lactobacillus].	25.27	562	346	20	103	629	85	607	2e-19	103
rs:WP_028527339	DNA topoisomerase I [Ruminococcus gauvreauii].	23.92	627	380	22	90	671	67	641	2e-19	103
tr:A0A0B8PCN3_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.99	621	364	22	57	633	83	639	2e-19	103
rs:XP_004442433	PREDICTED: DNA topoisomerase 3-beta-1 [Ceratotherium simum simum].	23.33	630	395	23	3	585	5	593	2e-19	103
rs:WP_006442126	DNA topoisomerase I [[Clostridium] hylemonae].	23.20	651	397	24	3	616	5	589	2e-19	103
rs:WP_029689028	DNA topoisomerase I [Thermoanaerobacter sp. A7A].	24.62	585	352	20	90	629	67	607	2e-19	103
rs:XP_009938839	PREDICTED: DNA topoisomerase 3-beta-1 [Opisthocomus hoazin].	23.06	607	386	19	3	564	5	575	2e-19	103
rs:WP_006736530	DNA topoisomerase I [Lactobacillus iners].	25.27	562	346	20	103	629	85	607	2e-19	103
rs:WP_001286963	MULTISPECIES: DNA topoisomerase I [Bacillus].	23.75	560	370	20	105	635	82	613	2e-19	103
rs:WP_011541512	DNA topoisomerase I [Sphingopyxis alaskensis].	23.09	667	422	25	1	629	1	614	2e-19	103
rs:WP_039179783	DNA topoisomerase I [Halomonas hydrothermalis].	25.72	486	279	18	186	633	201	642	2e-19	103
rs:WP_012097495	DNA topoisomerase I [Anaeromyxobacter sp. Fw109-5].	23.55	637	378	25	76	646	88	681	2e-19	103
rs:WP_045026640	DNA topoisomerase I [Photobacterium phosphoreum].	24.37	595	378	22	73	633	83	639	2e-19	103
rs:WP_025083276	DNA topoisomerase I [Lactobacillus fuchuensis].	24.30	572	370	20	90	629	68	608	2e-19	103
tr:C2P2H6_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.75	560	370	20	105	635	52	583	2e-19	103
rs:WP_000246604	DNA topoisomerase I [Streptococcus agalactiae].	24.33	559	353	22	103	630	99	618	2e-19	103
rs:WP_002442541	DNA topoisomerase I [Staphylococcus caprae].	24.19	558	358	20	103	629	80	603	2e-19	103
rs:WP_013275886	DNA topoisomerase I [Thermosediminibacter oceani].	23.15	717	431	28	3	675	5	645	2e-19	103
tr:C3C6F6_BACTU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.93	560	369	20	105	635	75	606	2e-19	103
rs:WP_026566452	DNA topoisomerase I [Bacillus sp. UNC41MFS5].	24.02	562	367	19	105	635	82	614	2e-19	103
rs:WP_022784507	DNA topoisomerase I [Lachnospiraceae bacterium NK4A179].	24.16	567	352	18	90	616	67	595	2e-19	103
rs:WP_032583635	DNA topoisomerase I, partial [Bacteroides fragilis].	31.96	219	131	7	186	394	3	213	2e-19	99.4
rs:XP_008439059	PREDICTED: DNA topoisomerase 3-beta-1 [Cucumis melo].	23.04	664	442	23	3	630	7	637	2e-19	103
rs:WP_040941924	DNA topoisomerase I [Xanthomonas campestris].	24.43	573	345	20	3	538	5	526	2e-19	103
rs:WP_012521875	DNA topoisomerase I [Phenylobacterium zucineum].	21.49	684	426	22	1	630	1	627	2e-19	103
rs:WP_028025214	DNA topoisomerase I [Enterovibrio calviensis].	24.47	609	356	20	74	633	86	639	2e-19	103
rs:WP_004407604	DNA topoisomerase III, partial [Pseudomonas syringae].	25.82	275	188	5	362	629	1	266	2e-19	99.8
rs:WP_027069793	DNA topoisomerase I [Lysobacter defluvii].	23.78	572	350	18	3	538	5	526	2e-19	103
rs:WP_022054850	DNA topoisomerase [Coprobacillus sp. CAG:605].	24.58	651	400	25	15	629	7	602	2e-19	103
rs:XP_009329018	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Pygoscelis adeliae].	22.90	607	387	19	3	564	5	575	2e-19	103
rs:WP_040359782	DNA topoisomerase [Collinsella aerofaciens].	24.92	598	357	25	58	616	109	653	2e-19	103
rs:WP_044335050	DNA topoisomerase I [Sphingomonas sp. WHSC-8].	23.37	676	409	24	1	629	1	614	2e-19	103
rs:WP_022093857	DNA topoisomerase [Collinsella sp. CAG:166].	24.92	598	357	25	58	616	109	653	2e-19	103
rs:WP_044257728	DNA topoisomerase I [Citrobacter sp. JT3].	23.71	599	381	19	73	633	74	634	2e-19	103
rs:WP_022157133	DNA topoisomerase [Firmicutes bacterium CAG:145].	25.44	574	356	23	90	631	82	615	2e-19	103
rs:WP_044499834	DNA topoisomerase I [Pseudomonas sp. 12M76_air].	23.78	593	381	19	74	633	83	637	2e-19	103
rs:WP_028447198	DNA topoisomerase I [Chitinimonas koreensis].	23.48	673	405	22	3	630	5	612	2e-19	103
rs:WP_042595233	DNA topoisomerase I [Xanthomonas campestris].	24.43	573	345	20	3	538	5	526	2e-19	103
rs:XP_005054966	PREDICTED: DNA topoisomerase 3-beta-1 [Ficedula albicollis].	22.73	607	388	19	3	564	5	575	2e-19	103
rs:WP_039229698	DNA topoisomerase I [Alteromonas macleodii].	25.53	615	357	26	65	629	75	638	2e-19	103
rs:WP_001286960	MULTISPECIES: DNA topoisomerase I [Bacillus].	23.75	560	370	20	105	635	82	613	2e-19	103
rs:WP_003069065	DNA topoisomerase I [Streptococcus intermedius].	24.00	575	372	21	83	629	55	592	2e-19	103
rs:WP_043000535	MULTISPECIES: DNA topoisomerase I [Citrobacter].	23.71	599	381	19	73	633	74	634	2e-19	103
rs:WP_035579838	DNA topoisomerase I [Halomonas sp. TG39a].	25.42	598	357	20	76	633	94	642	2e-19	103
rs:WP_014533317	DNA topoisomerase I [Staphylococcus lugdunensis].	25.58	559	345	23	103	629	80	599	2e-19	103
rs:WP_039483662	DNA topoisomerase I [Vibrio sinaloensis].	24.25	503	313	14	163	633	173	639	2e-19	103
rs:WP_036190436	DNA topoisomerase I [Marinobacterium sp. AK27].	24.09	602	373	21	72	633	86	643	2e-19	103
rs:WP_001286966	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	23.93	560	369	20	105	635	82	613	2e-19	103
rs:WP_027266315	DNA topoisomerase I [Legionella pneumophila].	25.94	636	389	29	55	641	29	631	2e-19	103
rs:XP_010301850	PREDICTED: DNA topoisomerase 3-beta-1 [Balearica regulorum gibbericeps].	22.90	607	387	19	3	564	5	575	2e-19	103
rs:WP_008820261	DNA topoisomerase, partial [Fusobacterium periodonticum].	25.28	617	374	21	2	589	12	570	2e-19	103
rs:WP_019376482	DNA topoisomerase I [Virgibacillus halodenitrificans].	24.56	570	358	21	103	635	80	614	2e-19	103
rs:WP_000513598	topoisomerase I [Salmonella enterica].	24.20	595	383	20	73	633	74	634	2e-19	103
rs:NP_639100	DNA topoisomerase I [Xanthomonas campestris pv. campestris str. ATCC 33913].	24.43	573	345	20	3	538	5	526	2e-19	103
tr:E6QPP2_9ZZZZ	SubName: Full=DNA topoisomerase 1 (DNA topoisomerase I) (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) {ECO:0000313|EMBL:CBI09213.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI09213.1};	24.40	586	337	22	100	629	77	612	2e-19	103
tr:E8N5B1_ANATU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.26	602	379	20	76	630	120	685	2e-19	103
rs:WP_009286991	MULTISPECIES: DNA topoisomerase I [Halomonas].	25.42	598	357	20	76	633	94	642	2e-19	103
rs:XP_012499600	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Propithecus coquereli].	22.79	610	384	20	3	564	5	575	2e-19	103
rs:WP_014784854	DNA topoisomerase [Terriglobus roseus].	23.31	682	407	22	3	624	5	630	2e-19	103
rs:WP_039232450	DNA topoisomerase I [Alteromonas macleodii].	25.53	615	357	26	65	629	75	638	2e-19	103
rs:XP_009971210	PREDICTED: DNA topoisomerase 3-beta-1 [Tyto alba].	22.90	607	387	19	3	564	5	575	2e-19	103
rs:WP_026585548	DNA topoisomerase I [Bacillus sp. J33].	23.19	565	369	21	105	636	82	614	2e-19	103
tr:C2T4T6_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.75	560	370	20	105	635	52	583	2e-19	102
rs:WP_034234041	DNA topoisomerase I [Lachnospiraceae bacterium AC2029].	24.61	581	361	19	90	634	67	606	2e-19	103
rs:WP_004231665	DNA topoisomerase I [Streptococcus equinus].	23.35	561	356	21	103	630	105	624	2e-19	103
rs:WP_011216475	DNA topoisomerase I [Legionella pneumophila].	25.94	636	389	29	55	641	29	631	2e-19	103
rs:WP_021817184	topoisomerase I [Halomonas sp. BJGMM-B45].	25.41	484	284	16	186	633	201	643	2e-19	103
rs:WP_032272977	DNA topoisomerase III, partial [Escherichia coli].	24.91	277	190	5	355	614	7	282	2e-19	100
rs:WP_046988255	DNA topoisomerase III, partial [Thermomonas brevis].	31.67	180	112	4	1	177	1	172	2e-19	97.1
rs:WP_034102734	DNA topoisomerase I [Desulfotomaculum sp. BICA1-6].	23.80	563	361	18	88	616	62	590	2e-19	103
rs:WP_012137309	DNA topoisomerase I subunit omega [Marinobacter lipolyticus].	23.85	478	302	14	186	633	200	645	2e-19	103
rs:WP_036105439	DNA topoisomerase I [Mangrovibacter sp. MFB070].	23.24	598	385	17	73	633	74	634	2e-19	103
rs:WP_026182515	DNA topoisomerase I [Leeia oryzae].	24.75	602	365	19	76	630	53	613	2e-19	103
rs:WP_016994084	DNA topoisomerase I [Lysinibacillus boronitolerans].	23.92	556	365	17	103	629	80	606	2e-19	103
rs:WP_021092005	DNA topoisomerase I [Campylobacter concisus].	24.44	536	338	19	77	578	50	552	2e-19	102
rs:WP_017030334	topoisomerase I [Vibrio breoganii].	23.83	621	365	24	57	633	83	639	2e-19	103
rs:WP_018660050	DNA topoisomerase I [Bacillus acidiproducens].	23.43	559	373	20	105	635	82	613	2e-19	103
rs:WP_028772459	DNA topoisomerase I [Shewanella waksmanii].	23.53	595	377	17	74	631	88	641	2e-19	103
rs:WP_041817766	DNA topoisomerase I [Lactobacillus sanfranciscensis].	23.38	663	408	25	2	629	24	621	2e-19	103
rs:WP_046208644	DNA topoisomerase I [Staphylococcus cohnii].	23.62	563	380	17	90	629	67	602	2e-19	102
tr:F7ES60_XENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.84	626	403	21	3	585	5	593	2e-19	103
rs:WP_015045631	topoisomerase I [Simiduia agarivorans].	24.26	474	295	14	186	629	201	640	2e-19	103
rs:WP_010381554	topoisomerase I [Pseudoalteromonas rubra].	24.32	592	382	19	72	631	84	641	2e-19	103
tr:K2GJ82_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKE30519.1};	27.55	265	183	5	424	681	35	297	2e-19	99.8
rs:WP_022238238	DNA topoisomerase [Clostridium sp. CAG:343].	25.89	475	287	18	90	534	67	506	2e-19	102
rs:WP_022523166	DNA topoisomerase 1 [Halomonas sp. A3H3].	25.42	598	357	20	76	633	94	642	2e-19	103
rs:XP_012499599	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Propithecus coquereli].	23.11	610	382	21	3	564	74	644	2e-19	103
rs:WP_018372628	DNA topoisomerase I [Streptococcus merionis].	23.57	577	372	17	83	629	73	610	2e-19	103
tr:T0YYR8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD40801.1}; Flags: Fragment;	31.73	208	123	3	172	360	1	208	2e-19	98.2
rs:WP_022488428	DNA topoisomerase [Clostridium sp. CAG:914].	22.64	658	414	19	1	629	3	594	2e-19	102
tr:J6QMH7_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJX69505.1}; Flags: Fragment;	27.41	270	180	6	413	667	16	284	2e-19	99.8
tr:U1QZT7_9EURY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.62	754	455	32	1	661	1	711	2e-19	103
rs:WP_036350533	DNA topoisomerase, partial [Microvirga sp. BSC39].	24.07	536	336	21	44	521	27	549	2e-19	103
tr:F9MPK7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.69	229	155	3	271	493	3	231	2e-19	98.6
rs:XP_011172545	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Solenopsis invicta].	21.89	676	445	21	3	630	5	645	2e-19	103
rs:WP_025443358	DNA topoisomerase I [Campylobacter coli].	25.05	531	336	17	81	579	55	555	2e-19	102
rs:WP_001286964	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	23.75	560	370	20	105	635	82	613	2e-19	102
rs:XP_011587887	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Aquila chrysaetos canadensis].	22.90	607	387	19	3	564	5	575	2e-19	103
rs:WP_019312541	DNA topoisomerase I [Streptococcus mutans].	23.84	583	366	23	83	630	78	617	2e-19	102
rs:WP_039584828	DNA topoisomerase III, partial [Xanthomonas axonopodis].	30.47	233	141	7	1	222	1	223	2e-19	98.2
rs:WP_035148559	DNA topoisomerase I [Clostridium tetanomorphum].	25.69	650	383	23	2	616	4	588	2e-19	102
rs:WP_031674614	DNA topoisomerase I [Listeria monocytogenes].	23.20	556	368	19	103	629	80	605	2e-19	102
rs:WP_001286952	DNA topoisomerase I [Bacillus cereus].	23.93	560	369	20	105	635	82	613	2e-19	102
rs:WP_038483622	DNA topoisomerase I [Halomonas campaniensis].	25.08	594	375	19	72	633	87	642	2e-19	103
rs:WP_014842657	DNA topoisomerase I [Legionella pneumophila].	25.94	636	389	29	55	641	29	631	2e-19	103
rs:WP_016743312	DNA topoisomerase I [Brevibacillus brevis].	24.29	564	366	24	103	635	80	613	2e-19	102
rs:WP_025209884	DNA topoisomerase I [Hippea sp. KM1].	22.82	710	451	24	1	679	1	644	2e-19	102
rs:WP_044642672	DNA topoisomerase I [Thermoactinomycetaceae bacterium GD1].	23.74	577	374	22	88	630	62	606	2e-19	102
rs:WP_010948299	DNA topoisomerase I [Legionella pneumophila].	25.94	636	389	29	55	641	29	631	2e-19	103
tr:C2N519_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.75	560	370	20	105	635	52	583	2e-19	102
rs:WP_031280468	DNA topoisomerase III, partial [Peptoclostridium difficile].	42.50	120	66	3	100	218	7	124	2e-19	95.9
tr:X5MHV7_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.89	632	396	24	55	629	2	605	2e-19	103
rs:WP_010629088	topoisomerase I [Halomonas sp. KM-1].	24.87	599	363	22	74	633	92	642	2e-19	103
rs:WP_038839607	DNA topoisomerase I [Legionella pneumophila].	25.94	636	389	29	55	641	29	631	2e-19	103
rs:WP_034732693	DNA topoisomerase I [Idiomarina sp. MCCC 1A10513].	23.64	643	396	22	76	673	88	680	2e-19	103
rs:WP_002351757	DNA topoisomerase I [Streptococcus mutans].	23.54	582	369	21	83	630	78	617	2e-19	102
rs:NP_001182501	DNA topoisomerase 3-beta-1 isoform 1 [Xenopus (Silurana) tropicalis].	22.84	626	403	21	3	585	5	593	2e-19	103
tr:A0A097ART4_THEKI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.16	632	366	26	90	671	67	641	2e-19	102
tr:A0A0B8NR25_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.99	621	364	22	57	633	83	639	2e-19	103
rs:WP_024105897	topoisomerase I [Dickeya dianthicola].	24.31	650	386	25	75	673	81	675	2e-19	103
rs:WP_041081072	DNA topoisomerase I [Thermotoga profunda].	23.84	646	392	22	2	612	3	583	2e-19	102
rs:WP_011835151	DNA topoisomerase I [Lactococcus lactis].	25.00	556	351	20	103	629	101	619	2e-19	102
rs:WP_035641699	DNA topoisomerase I [Lachnospiraceae bacterium FE2018].	23.52	557	364	19	90	616	67	591	2e-19	102
tr:A4EC43_9ACTN	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	25.08	598	356	26	58	616	31	575	2e-19	103
rs:WP_041334940	DNA topoisomerase I, partial [Roseiflexus sp. RS-1].	23.29	687	406	24	2	630	4	627	2e-19	102
rs:WP_002352642	DNA topoisomerase, partial [Enterococcus faecium].	27.50	240	169	2	347	581	37	276	3e-19	99.4
rs:WP_045642951	DNA topoisomerase I [Peptococcaceae bacterium BRH_c8a].	23.80	563	361	18	88	616	79	607	3e-19	102
rs:WP_010666274	DNA topoisomerase I [Acetobacter aceti].	22.74	642	393	26	55	629	28	633	3e-19	103
rs:WP_024299256	DNA topoisomerase I [Methylosarcina lacus].	23.22	676	412	25	3	630	5	621	3e-19	103
rs:WP_008163680	DNA topoisomerase I [Natronorubrum sulfidifaciens].	22.64	720	447	31	1	661	1	669	3e-19	103
rs:WP_040277260	DNA topoisomerase I [Xanthomonas citri].	24.22	578	340	20	3	538	5	526	3e-19	103
rs:WP_039395112	DNA topoisomerase I, partial [Novosphingobium sp. MBES04].	22.39	670	424	23	1	629	1	615	3e-19	103
tr:D5HI49_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.62	566	338	21	90	616	81	602	3e-19	102
rs:WP_009330770	MULTISPECIES: DNA topoisomerase I [Bacillus].	23.36	565	368	19	105	636	82	614	3e-19	102
rs:WP_044157398	DNA topoisomerase I [Salinibacillus aidingensis].	24.34	567	358	23	105	635	82	613	3e-19	102
rs:WP_021320765	DNA topoisomerase I [Streptococcus equi].	24.01	579	370	21	83	630	84	623	3e-19	102
rs:WP_046157929	DNA topoisomerase I [Chromobacterium vaccinii].	23.63	584	377	17	84	630	61	612	3e-19	102
rs:WP_043949226	DNA topoisomerase I [Candidatus Phaeomarinobacter ectocarpi].	23.56	679	416	27	3	629	5	632	3e-19	103
rs:XP_009076161	PREDICTED: DNA topoisomerase 3-beta-1 [Acanthisitta chloris].	22.73	607	388	19	3	564	5	575	3e-19	103
rs:WP_038674305	DNA topoisomerase I [Streptococcus equi].	24.01	579	370	21	83	630	84	623	3e-19	102
rs:WP_021678009	hypothetical protein, partial [Porphyromonas gingivalis].	33.18	214	131	8	466	676	64	268	3e-19	99.4
rs:WP_021750753	MULTISPECIES: DNA topoisomerase I [Oscillibacter].	23.29	614	408	21	90	673	68	648	3e-19	103
rs:WP_042958252	DNA topoisomerase, partial [Enterococcus faecium].	24.76	311	218	6	372	667	12	321	3e-19	100
rs:WP_006352524	DNA topoisomerase I [Lactobacillus amylolyticus].	25.65	577	338	25	103	635	93	622	3e-19	102
tr:T0TG73_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.84	562	352	23	103	630	73	592	3e-19	102
gp:CP002094_1249	DNA topoisomerase I [Lactococcus lactis subsp. cremoris NZ9000]	25.00	556	351	20	103	629	82	600	3e-19	102
rs:WP_039223928	DNA topoisomerase I [Alteromonas marina].	25.53	615	357	26	65	629	75	638	3e-19	103
rs:WP_034825430	DNA topoisomerase I [Hyphomonas sp. T16B2].	24.12	684	406	31	1	629	1	626	3e-19	103
rs:WP_042670629	DNA topoisomerase I [Streptococcus equi].	24.05	578	371	19	83	630	84	623	3e-19	102
rs:WP_025148338	DNA topoisomerase I [Bacillus sp. H1a].	23.88	582	384	21	105	655	82	635	3e-19	102
rs:WP_010364821	topoisomerase I [Pseudoalteromonas citrea].	23.89	607	355	23	76	631	91	641	3e-19	103
rs:WP_033628392	DNA topoisomerase, partial [Enterococcus faecalis].	27.20	261	169	5	293	541	84	335	3e-19	99.8
rs:WP_016854570	topoisomerase I [Halomonas smyrnensis].	24.85	487	286	16	186	633	201	646	3e-19	103
rs:WP_013278603	DNA topoisomerase I [Acetohalobium arabaticum].	24.96	565	341	19	90	616	67	586	3e-19	102
tr:A0A068X0K2_ECHGR	SubName: Full=DNA topoisomerase 3 beta 1 {ECO:0000313|EMBL:CDS23493.1};	22.69	692	422	27	3	629	29	672	3e-19	103
rs:WP_008572030	DNA topoisomerase I [Xanthomonas perforans].	24.26	573	346	20	3	538	5	526	3e-19	103
tr:D5T991_LEGP2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.94	636	389	29	55	641	3	605	3e-19	102
rs:WP_025080665	DNA topoisomerase I [Lactobacillus hamsteri].	24.39	570	354	23	103	635	93	622	3e-19	102
rs:WP_022249372	DNA topoisomerase [Eubacterium sp. CAG:274].	23.99	642	382	27	90	658	69	677	3e-19	102
rs:WP_026906107	DNA topoisomerase I [Paucisalibacillus globulus].	25.00	572	353	24	103	635	80	614	3e-19	102
rs:WP_037573320	DNA topoisomerase I [Staphylococcus chromogenes].	23.81	567	375	21	90	629	67	603	3e-19	102
rs:WP_006418410	DNA topoisomerase I [Eremococcus coleocola].	25.69	576	348	21	90	629	68	599	3e-19	102
rs:WP_022365994	DNA topoisomerase [Firmicutes bacterium CAG:341].	24.89	687	395	31	2	637	3	619	3e-19	102
rs:WP_029820479	DNA topoisomerase I [Xanthomonas alfalfae].	24.26	573	346	20	3	538	5	526	3e-19	102
rs:WP_013320619	DNA topoisomerase I [Cyanothece sp. PCC 7822].	24.57	578	353	17	85	615	67	608	3e-19	102
rs:XP_003738127	PREDICTED: DNA topoisomerase 3-beta-1-like [Metaseiulus occidentalis].	23.35	591	390	17	3	560	8	568	3e-19	103
rs:XP_008337495	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Malus domestica].	23.09	550	373	15	105	631	55	577	3e-19	102
rs:WP_034740925	DNA topoisomerase I [Bacillus wakoensis].	24.55	558	361	22	103	630	80	607	3e-19	102
rs:WP_004229276	DNA topoisomerase I [Lysinibacillus fusiformis].	24.10	556	364	18	103	629	80	606	3e-19	102
rs:XP_001354695	GA17464 [Drosophila pseudoobscura pseudoobscura].	24.65	495	316	17	188	655	211	675	3e-19	103
rs:WP_014334730	DNA topoisomerase I [Streptococcus infantarius].	23.84	562	352	23	103	630	105	624	3e-19	102
rs:WP_042823960	DNA topoisomerase I [Xanthomonas axonopodis].	24.26	573	346	20	3	538	5	526	3e-19	102
rs:WP_035096835	DNA topoisomerase I [Devosia sp. LC5].	22.89	686	410	22	1	629	1	624	3e-19	103
rs:WP_000246601	DNA topoisomerase I [Streptococcus agalactiae].	24.33	559	353	22	103	630	99	618	3e-19	102
rs:XP_008167010	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Chrysemys picta bellii].	22.93	615	377	22	3	564	5	575	3e-19	103
rs:WP_028518733	DNA topoisomerase I [Ruminococcus flavefaciens].	23.85	566	351	20	90	616	66	590	3e-19	102
rs:WP_033644711	DNA topoisomerase, partial [Enterococcus faecium].	24.76	311	218	6	372	667	11	320	3e-19	100
rs:WP_012553896	DNA topoisomerase I [Gluconacetobacter diazotrophicus].	22.22	639	404	23	55	630	28	636	3e-19	103
rs:WP_022850531	DNA topoisomerase [Geovibrio sp. L21-Ace-BES].	24.78	577	375	17	83	630	60	606	3e-19	102
tr:R8ZQR5_9LEPT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	24.62	520	319	13	46	536	6	481	3e-19	102
rs:XP_011000015	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Populus euphratica].	22.46	610	400	19	65	631	20	599	3e-19	102
rs:WP_039928916	DNA topoisomerase I [Leptospira yanagawae].	24.62	520	319	13	46	536	7	482	3e-19	102
rs:WP_039683338	DNA topoisomerase I [Tateyamaria sp. ANG-S1].	22.25	692	406	26	1	629	1	623	3e-19	102
rs:WP_029274672	DNA topoisomerase I [Pedobacter borealis].	25.78	516	331	15	77	578	54	531	3e-19	102
rs:WP_037910128	DNA topoisomerase I [Sulfitobacter mediterraneus].	22.11	683	416	23	1	629	1	621	3e-19	102
rs:XP_002988753	hypothetical protein SELMODRAFT_427375 [Selaginella moellendorffii].	24.86	539	332	20	38	536	249	754	3e-19	103
rs:WP_022246783	DNA topoisomerase [Clostridium sp. CAG:306].	24.56	684	395	26	3	639	18	627	3e-19	102
rs:WP_045797922	DNA topoisomerase I [Streptococcus equinus].	23.84	562	352	23	103	630	105	624	3e-19	102
rs:WP_046800293	DNA topoisomerase I [Agrobacterium sp. LC34].	23.12	705	398	28	1	630	1	636	3e-19	102
rs:WP_039425451	DNA topoisomerase I [Vibrio navarrensis].	24.06	611	376	21	57	633	83	639	3e-19	102
rs:WP_039690742	DNA topoisomerase I [Streptococcus equinus].	23.84	562	352	23	103	630	105	624	3e-19	102
gp:CP003885_439	DNA topoisomerase I [Legionella pneumophila subsp. pneumophila LPE509]	25.94	636	389	29	55	641	3	605	3e-19	102
rs:WP_033624486	DNA topoisomerase, partial [Enterococcus faecalis].	27.37	358	219	12	154	483	20	364	3e-19	100
rs:XP_012346286	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Apis florea].	21.35	679	445	20	3	630	5	645	3e-19	102
rs:WP_024344084	DNA topoisomerase I [Streptococcus equinus].	23.84	562	352	23	103	630	105	624	3e-19	102
rs:WP_027267691	DNA topoisomerase I [Legionella pneumophila].	25.94	636	389	29	55	641	29	631	3e-19	102
tr:A7BSD2_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.94	667	402	22	3	616	5	612	3e-19	102
rs:XP_008507640	PREDICTED: DNA topoisomerase 3-beta-1 [Equus przewalskii].	22.87	621	394	22	3	585	5	578	3e-19	102
rs:WP_038151015	DNA topoisomerase I [Veillonella montpellierensis].	23.56	573	369	22	90	629	135	671	3e-19	102
rs:WP_024108762	topoisomerase I [Dickeya dianthicola].	24.31	650	386	25	75	673	81	675	3e-19	102
rs:WP_011052536	DNA topoisomerase I [Xanthomonas citri].	24.26	573	346	20	3	538	5	526	3e-19	102
rs:WP_040030611	DNA topoisomerase I [Staphylococcus cohnii].	24.30	568	370	18	90	629	67	602	3e-19	102
rs:WP_007816808	DNA topoisomerase I [Roseobacter sp. AzwK-3b].	22.07	716	436	25	1	659	1	651	3e-19	102
rs:WP_019781670	DNA topoisomerase I [Streptococcus sobrinus].	23.71	582	366	22	83	629	87	625	3e-19	102
rs:WP_026756381	DNA topoisomerase I [Sediminimonas qiaohouensis].	23.27	709	435	29	1	659	1	650	3e-19	102
rs:WP_002281097	DNA topoisomerase I [Streptococcus mutans].	23.67	583	367	23	83	630	78	617	3e-19	102
rs:WP_043025818	DNA topoisomerase I [Streptococcus equi].	23.88	578	372	20	83	630	84	623	3e-19	102
rs:WP_013681861	DNA topoisomerase I [Hippea maritima].	23.99	667	403	26	1	629	1	601	3e-19	102
rs:WP_005911395	MULTISPECIES: DNA topoisomerase I [Xanthomonas].	24.26	573	346	20	3	538	5	526	3e-19	102
rs:WP_011348788	MULTISPECIES: DNA topoisomerase I [Xanthomonas].	24.26	573	346	20	3	538	5	526	3e-19	102
rs:WP_018975043	DNA topoisomerase I [Saccharibacillus kuerlensis].	24.32	584	377	21	88	636	62	615	3e-19	102
rs:WP_039568675	DNA topoisomerase I [Xanthomonas axonopodis].	24.26	573	346	20	3	538	5	526	3e-19	102
rs:WP_035419183	MULTISPECIES: DNA topoisomerase I [Bacillus].	25.44	574	359	24	90	629	67	605	3e-19	102
tr:T0NBF8_9CLOT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EQB87485.1};	28.96	259	151	8	3	238	5	253	3e-19	99.4
rs:WP_026506230	DNA topoisomerase I [Butyrivibrio sp. NC3005].	24.10	556	361	18	90	616	69	592	3e-19	102
rs:WP_024532816	DNA topoisomerase I [Streptococcus suis].	23.22	577	375	19	83	629	72	610	3e-19	102
rs:WP_044423544	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	30.00	240	158	6	269	498	6	245	3e-19	98.6
rs:WP_005927347	DNA topoisomerase I [Xanthomonas axonopodis].	24.26	573	346	20	3	538	5	526	3e-19	102
rs:XP_009947595	PREDICTED: DNA topoisomerase 3-beta-1 [Leptosomus discolor].	22.90	607	387	19	3	564	5	575	3e-19	102
rs:WP_007544534	DNA topoisomerase I [Listeria fleischmannii].	24.65	568	355	23	105	635	82	613	3e-19	102
rs:WP_039444195	DNA topoisomerase I [Vibrio navarrensis].	24.06	611	376	21	57	633	83	639	3e-19	102
rs:NP_001082554	topoisomerase (DNA) III beta [Xenopus laevis].	22.50	631	399	20	3	585	5	593	3e-19	102
rs:WP_042407113	DNA topoisomerase I [Geobacillus caldoxylosilyticus].	24.36	509	328	18	157	635	132	613	3e-19	102
rs:WP_009533718	DNA topoisomerase I [Stomatobaculum longum].	23.38	556	367	16	90	616	67	592	3e-19	102
rs:WP_028782775	DNA topoisomerase I [Thalassobacillus devorans].	24.60	569	358	23	103	635	80	613	3e-19	102
rs:WP_022476334	DNA topoisomerase [Clostridium sp. CAG:273].	24.75	610	334	30	90	636	67	614	3e-19	102
rs:WP_039433148	DNA topoisomerase I [Vibrio navarrensis].	24.06	611	376	21	57	633	83	639	3e-19	102
rs:WP_034802148	DNA topoisomerase I [Eubacterium sp. AB3007].	23.64	571	360	20	103	636	83	614	3e-19	102
rs:XP_005334534	PREDICTED: DNA topoisomerase 3-beta-1 [Ictidomys tridecemlineatus].	23.53	629	395	22	3	585	5	593	3e-19	102
rs:WP_002282653	DNA topoisomerase I [Streptococcus mutans].	23.67	583	367	23	83	630	78	617	3e-19	102
rs:WP_014976305	topoisomerase I [Alteromonas macleodii].	25.53	615	357	26	65	629	75	638	3e-19	102
rs:WP_002287969	DNA topoisomerase I [Streptococcus mutans].	23.67	583	367	23	83	630	78	617	3e-19	102
rs:WP_024783829	DNA topoisomerase I [Streptococcus mutans].	23.67	583	367	23	83	630	78	617	3e-19	102
rs:WP_036737880	DNA topoisomerase I [Paracoccus halophilus].	22.70	696	428	27	1	648	1	634	3e-19	102
rs:WP_014091221	DNA topoisomerase I [Xanthomonas alfalfae].	24.26	573	346	20	3	538	5	526	3e-19	102
rs:XP_005021234	PREDICTED: DNA topoisomerase 3-beta-1 [Anas platyrhynchos].	22.90	607	387	19	3	564	5	575	3e-19	102
rs:WP_016520265	DNA topoisomerase I [Treponema socranskii].	25.67	600	360	23	83	643	72	624	3e-19	102
rs:WP_031472082	DNA topoisomerase I [Eubacterium desmolans].	22.95	645	412	21	2	616	3	592	3e-19	102
rs:WP_002283154	DNA topoisomerase I [Streptococcus mutans].	23.67	583	367	23	83	630	78	617	3e-19	102
rs:WP_002272153	DNA topoisomerase I [Streptococcus mutans].	23.67	583	367	23	83	630	78	617	3e-19	102
rs:WP_015463664	DNA topoisomerase I [Xanthomonas axonopodis].	24.26	573	346	20	3	538	5	526	3e-19	102
rs:WP_011744019	DNA topoisomerase I [Chlorobium phaeobacteroides].	24.67	604	366	19	76	629	63	627	3e-19	102
rs:WP_004042619	DNA topoisomerase I, partial [Lactobacillus sp. ASF360].	26.80	582	325	29	103	635	92	621	3e-19	102
rs:WP_002283689	DNA topoisomerase I [Streptococcus mutans].	23.67	583	367	23	83	630	78	617	3e-19	102
tr:C2QFW7_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.93	560	369	20	105	635	52	583	3e-19	102
rs:WP_016914091	topoisomerase I [Halomonas stevensii].	25.71	490	274	19	186	633	201	642	3e-19	102
rs:WP_017157050	DNA topoisomerase I [Xanthomonas axonopodis].	24.26	573	346	20	3	538	5	526	3e-19	102
tr:B4U2W8_STREM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.01	579	370	21	83	630	87	626	3e-19	102
rs:WP_028945924	DNA topoisomerase I [Pseudomonas vranovensis].	24.11	593	377	21	74	633	87	639	3e-19	102
rs:XP_010186423	PREDICTED: DNA topoisomerase 3-beta-1 [Mesitornis unicolor].	22.73	607	388	19	3	564	5	575	3e-19	102
rs:WP_019314697	DNA topoisomerase I [Streptococcus mutans].	23.67	583	367	23	83	630	78	617	3e-19	102
rs:WP_002270391	DNA topoisomerase I [Streptococcus mutans].	23.67	583	367	23	83	630	78	617	3e-19	102
rs:WP_010393696	DNA topoisomerase I [Paracoccus sp. TRP].	22.68	710	438	27	1	659	1	650	3e-19	102
rs:WP_012094926	DNA topoisomerase I [Bacillus cytotoxicus].	23.04	560	374	20	105	635	82	613	4e-19	102
rs:XP_001963417	GF20299 [Drosophila ananassae].	25.85	383	247	11	188	560	211	566	4e-19	102
rs:WP_012467319	DNA topoisomerase I [Chlorobium limicola].	24.51	608	362	19	76	629	63	627	4e-19	102
tr:A0A0D6DDF9_STAAU	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:BAR08694.1};	23.83	470	304	13	187	629	7	449	4e-19	101
rs:WP_047137101	DNA topoisomerase I [Luteimonas sp. FCS-9].	24.48	572	346	19	3	538	5	526	4e-19	102
rs:WP_044904860	DNA topoisomerase I [[Clostridium] innocuum].	24.63	536	334	16	3	520	4	487	4e-19	102
rs:WP_025368922	DNA topoisomerase I [Buchnera aphidicola].	25.70	502	309	14	152	624	145	611	4e-19	102
rs:WP_016850507	DNA topoisomerase I [Xanthomonas axonopodis].	24.26	573	346	20	3	538	5	526	4e-19	102
rs:WP_041326303	DNA topoisomerase I [Ruminococcus champanellensis].	23.66	558	362	17	90	616	81	605	4e-19	102
rs:WP_042471896	DNA topoisomerase I [Bacillus sp. FF3].	23.02	556	370	17	103	629	80	606	4e-19	102
rs:WP_013264520	DNA topoisomerase I [Prevotella melaninogenica].	24.51	608	353	22	3	578	5	538	4e-19	102
rs:WP_003368297	DNA topoisomerase I [Clostridium botulinum].	23.83	705	398	24	2	630	4	645	4e-19	102
tr:D4LCS4_RUMC1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.66	596	388	19	55	616	28	590	4e-19	102
rs:WP_023433784	DNA topoisomerase I [Lutibaculum baratangense].	21.90	694	416	24	1	630	1	632	4e-19	102
tr:A0A073IAQ6_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KEJ87403.1};	34.78	138	81	4	1	135	1	132	4e-19	95.9
rs:WP_037212691	DNA topoisomerase I [Rhizobium sp. YR295].	23.44	691	413	29	1	630	1	636	4e-19	102
rs:WP_028093990	DNA topoisomerase I [Donghicola xiamenensis].	23.16	678	416	25	1	629	1	622	4e-19	102
rs:WP_033398064	DNA topoisomerase I [Fusobacterium russii].	26.52	607	354	25	2	577	5	550	4e-19	102
rs:WP_047066985	DNA topoisomerase I, partial [Enterobacter aerogenes].	23.42	619	367	22	60	633	78	634	4e-19	102
rs:WP_029420516	DNA topoisomerase I [Alicyclobacillus macrosporangiidus].	23.40	564	356	21	89	614	63	588	4e-19	102
tr:R3GZ90_ENTFL	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOJ98586.1};	28.47	281	160	7	337	611	15	260	4e-19	99.8
rs:WP_028928297	DNA topoisomerase I [Pseudoxanthomonas suwonensis].	26.01	469	292	15	103	538	80	526	4e-19	102
rs:WP_040965890	DNA topoisomerase I [Erythrobacter vulgaris].	23.12	679	413	27	1	629	1	620	4e-19	102
rs:WP_011676299	DNA topoisomerase I [Lactococcus lactis].	24.82	556	352	20	103	629	101	619	4e-19	102
rs:WP_008036521	DNA topoisomerase I [Rhodobacterales bacterium HTCC2255].	24.96	573	332	23	1	537	1	511	4e-19	102
rs:WP_038139440	hypothetical protein, partial [Thiomicrospira sp. Milos-T1].	26.10	502	311	18	55	536	27	488	4e-19	101
rs:XP_010510116	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Camelina sativa].	24.65	507	323	18	105	586	76	548	4e-19	102
rs:WP_019318811	DNA topoisomerase I [Streptococcus mutans].	23.67	583	367	23	83	630	78	617	4e-19	102
rs:WP_004611389	MULTISPECIES: DNA topoisomerase I [Clostridiales].	23.99	617	356	26	90	629	67	647	4e-19	102
rs:WP_019318257	DNA topoisomerase I [Streptococcus mutans].	23.37	582	370	21	83	630	78	617	4e-19	102
rs:WP_019805905	DNA topoisomerase I [Streptococcus mutans].	23.37	582	370	21	83	630	78	617	4e-19	102
rs:WP_039249168	DNA topoisomerase I [Clostridium novyi].	24.25	701	400	23	2	630	4	645	4e-19	102
rs:WP_003375272	DNA topoisomerase I [Clostridium botulinum].	24.22	644	398	19	2	616	4	586	4e-19	102
rs:WP_025426616	DNA topoisomerase I [Ensifer adhaerens].	23.05	694	412	27	1	630	1	636	4e-19	102
rs:WP_009834706	topoisomerase I [Marinomonas sp. MED121].	23.33	600	369	18	76	633	92	642	4e-19	102
rs:WP_020482931	DNA topoisomerase I [Methylomonas sp. MK1].	23.42	602	381	20	76	630	53	621	4e-19	102
tr:B1SFB3_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.84	562	352	23	103	630	123	642	4e-19	102
rs:WP_026858406	DNA topoisomerase I [Jeotgalicoccus psychrophilus].	23.98	563	354	21	103	629	80	604	4e-19	102
rs:XP_010077639	PREDICTED: DNA topoisomerase 3-beta-1 [Pterocles gutturalis].	22.90	607	387	20	3	564	5	575	4e-19	102
rs:WP_010491173	topoisomerase IA, partial [Lactobacillus zeae].	26.89	238	167	3	360	592	1	236	4e-19	99.4
rs:WP_003766673	DNA topoisomerase I [Listeria innocua].	22.92	554	368	19	105	629	82	605	4e-19	102
rs:WP_019773343	DNA topoisomerase I, partial [Streptococcus sobrinus].	23.71	582	366	22	83	629	85	623	4e-19	102
rs:XP_010144869	PREDICTED: DNA topoisomerase 3-beta-1 [Eurypyga helias].	22.90	607	387	19	3	564	5	575	4e-19	102
rs:WP_015222548	DNA topoisomerase I [Cyanobacterium stanieri].	24.83	580	329	20	3	530	4	528	4e-19	102
rs:WP_002265839	DNA topoisomerase I [Streptococcus mutans].	23.37	582	370	21	83	630	78	617	4e-19	102
rs:WP_045393156	DNA topoisomerase I [Enterobacter aerogenes].	23.42	619	367	22	60	633	78	634	4e-19	102
rs:WP_019160968	DNA topoisomerase I [Ruminococcus sp. JC304].	24.44	622	380	24	90	671	67	638	4e-19	102
rs:WP_044056878	DNA topoisomerase I [Alteromonas australica].	24.92	606	372	23	65	629	75	638	4e-19	102
gp:CP002904_1030	DNA topoisomerase I [Streptococcus equi subsp. zooepidemicus ATCC 35246]	24.01	579	370	21	83	630	87	626	4e-19	102
tr:W8IA30_ENSAD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.05	694	412	27	1	630	3	638	4e-19	102
rs:WP_039626232	DNA topoisomerase I [Vibrio ichthyoenteri].	24.04	495	324	12	163	633	173	639	4e-19	102
tr:G9Z6S3_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.18	612	371	24	60	633	90	646	4e-19	102
rs:WP_020057405	DNA topoisomerase I [alpha proteobacterium SCGC AAA076-C03].	24.96	573	332	23	1	537	1	511	4e-19	102
rs:WP_011887130	DNA topoisomerase I [Geobacillus thermodenitrificans].	24.75	505	319	18	157	630	132	606	4e-19	102
rs:WP_038257868	DNA topoisomerase I [Yokenella regensburgei].	23.69	612	374	22	60	633	78	634	4e-19	102
rs:WP_047067934	DNA topoisomerase I [Brevibacillus formosus].	24.33	563	367	19	103	635	80	613	4e-19	102
rs:WP_020743415	DNA topoisomerase I subunit omega [Alteromonas macleodii].	25.82	612	359	26	65	629	75	638	4e-19	102
rs:WP_039234307	DNA topoisomerase I [Clostridium sp. K25].	24.22	644	398	19	2	616	4	586	4e-19	102
rs:WP_017173006	DNA topoisomerase I, partial [Xanthomonas axonopodis].	24.26	573	346	20	3	538	5	526	4e-19	102
rs:WP_009144254	topoisomerase I [Succinatimonas hippei].	23.42	649	409	21	3	616	5	600	4e-19	102
rs:WP_013933412	DNA topoisomerase I [Zymomonas mobilis].	22.97	688	410	25	1	629	1	627	4e-19	102
rs:WP_015158856	DNA topoisomerase I [Chamaesiphon minutus].	25.26	574	352	22	81	614	61	597	4e-19	102
rs:WP_014292698	topoisomerase I [Oceanimonas sp. GK1].	24.21	599	371	20	74	633	88	642	4e-19	102
tr:K8AML0_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.14	609	366	23	73	633	88	648	4e-19	102
rs:WP_008981066	DNA topoisomerase I [Ruminococcaceae bacterium D16].	22.27	633	406	20	83	673	62	650	4e-19	102
rs:WP_040611552	DNA topoisomerase I, partial [Odoribacter laneus].	32.56	215	130	7	470	680	3	206	4e-19	97.4
rs:WP_043713736	DNA topoisomerase I [Symbiobacterium thermophilum].	22.42	620	372	20	88	634	70	653	4e-19	102
rs:WP_038862609	DNA topoisomerase I [Cronobacter muytjensii].	24.14	609	366	23	73	633	74	634	4e-19	102
rs:WP_000513596	topoisomerase I [Salmonella enterica].	24.03	595	384	20	73	633	74	634	4e-19	102
rs:WP_029883572	DNA topoisomerase I [Enterobacter sp. T1-1].	23.92	602	365	22	76	633	82	634	4e-19	102
rs:WP_010245426	DNA topoisomerase I [Peptoniphilus rhinitidis].	25.04	639	371	28	90	678	67	647	4e-19	102
rs:XP_009619600	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Nicotiana tomentosiformis].	21.73	626	426	19	35	631	5	595	4e-19	102
tr:T1CAM2_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD78318.1};	31.15	183	118	4	1	181	1	177	4e-19	97.8
rs:WP_002275904	DNA topoisomerase I [Streptococcus mutans].	23.67	583	367	23	83	630	78	617	4e-19	102
tr:A6QKL4_ONYPH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.35	568	353	19	88	629	65	587	4e-19	102
rs:XP_010510118	PREDICTED: DNA topoisomerase 3-beta isoform X4 [Camelina sativa].	24.65	507	323	18	105	586	6	478	4e-19	102
rs:WP_023026804	DNA topoisomerase I [Streptococcus sp. I-G2].	24.06	561	349	22	103	629	91	608	4e-19	102
rs:WP_027232501	DNA topoisomerase I [Phyllobacterium sp. UNC302MFCol5.2].	23.17	695	405	26	1	629	1	632	4e-19	102
rs:WP_041726937	DNA topoisomerase I, partial [Desulfurispirillum indicum].	23.58	653	393	21	2	616	5	589	4e-19	102
rs:WP_042838739	DNA topoisomerase I [Xanthomonas citri].	24.26	573	346	20	3	538	5	526	4e-19	102
rs:WP_043334996	DNA topoisomerase I [Belnapia moabensis].	23.36	625	377	21	55	610	28	619	4e-19	102
rs:WP_019638089	DNA topoisomerase I [Paenibacillus fonticola].	24.14	584	378	22	88	636	62	615	4e-19	102
tr:F4WE22_ACREC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.26	674	442	21	3	630	5	642	4e-19	102
rs:WP_002273112	DNA topoisomerase I [Streptococcus mutans].	24.44	581	365	24	83	630	78	617	4e-19	102
rs:WP_044447104	DNA topoisomerase I [Alteromonas australica].	24.92	606	372	23	65	629	75	638	4e-19	102
rs:WP_045685654	DNA topoisomerase I [Martelella endophytica].	23.09	706	397	31	1	630	1	636	4e-19	102
rs:WP_041878989	hypothetical protein [Candidatus Xenolissoclinum pacificiensis].	24.65	564	341	17	3	536	4	513	4e-19	102
rs:WP_028919946	DNA topoisomerase I [Pseudoxanthomonas suwonensis].	26.01	469	292	15	103	538	80	526	4e-19	102
rs:WP_002282013	DNA topoisomerase I [Streptococcus mutans].	23.67	583	367	23	83	630	78	617	4e-19	102
rs:WP_022600088	DNA topoisomerase I [Coprobacter fastidiosus].	24.05	553	357	16	77	612	54	560	4e-19	102
tr:G9EFA7_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.08	590	369	20	76	633	33	581	4e-19	102
rs:WP_022314822	DNA topoisomerase [Ruminococcus sp. CAG:382].	25.79	605	370	24	83	646	89	655	4e-19	102
rs:XP_009487010	PREDICTED: DNA topoisomerase 3-beta-1 [Pelecanus crispus].	22.73	607	388	19	3	564	5	575	4e-19	102
tr:E0PDM1_STREI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.82	561	359	20	103	630	144	663	4e-19	102
rs:WP_041598850	DNA topoisomerase I [Hahella chejuensis].	25.13	597	360	21	76	633	93	641	4e-19	102
rs:WP_009368920	DNA topoisomerase I [Bilophila sp. 4_1_30].	24.03	591	383	20	71	631	44	598	4e-19	102
rs:WP_009259245	DNA topoisomerase I [Lachnospiraceae bacterium 7_1_58FAA].	23.50	566	364	17	83	614	61	591	4e-19	102
rs:WP_022357103	DNA topoisomerase [Ruminococcus sp. CAG:379].	23.66	596	388	19	55	616	28	590	4e-19	102
rs:XP_009640102	PREDICTED: DNA topoisomerase 3-beta-1 [Egretta garzetta].	22.73	607	388	19	3	564	5	575	4e-19	102
rs:WP_011234261	topoisomerase I [Idiomarina loihiensis].	25.10	490	274	17	186	629	195	637	4e-19	102
rs:WP_037169524	DNA topoisomerase I [Rhizobium sp. CF258].	23.44	691	413	29	1	630	1	636	5e-19	102
rs:WP_002290910	DNA topoisomerase I [Streptococcus mutans].	23.67	583	367	23	83	630	78	617	5e-19	102
tr:A0A0B3A5K8_9ARCH	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KHO45195.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KHO45195.1};	25.06	435	265	16	222	631	5	403	5e-19	101
rs:WP_015407675	DNA topoisomerase I [Dehalococcoides mccartyi].	24.59	675	389	27	2	624	4	610	5e-19	102
rs:WP_038480781	DNA topoisomerase I [Bacillus lehensis].	24.52	571	368	19	90	629	67	605	5e-19	102
rs:WP_019773981	DNA topoisomerase I [Streptococcus sobrinus].	23.71	582	366	22	83	629	87	625	5e-19	102
rs:WP_027160116	DNA topoisomerase I [Methylobacter luteus].	24.76	517	314	21	157	630	136	620	5e-19	102
rs:WP_019773825	DNA topoisomerase I, partial [Streptococcus sobrinus].	23.71	582	366	22	83	629	6	544	5e-19	101
tr:Q67PC7_SYMTH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.42	620	372	20	88	634	62	645	5e-19	102
rs:WP_029760461	DNA topoisomerase I [Geobacillus thermodenitrificans].	24.75	505	319	18	157	630	132	606	5e-19	102
rs:WP_018658789	hypothetical protein [Allofustis seminis].	25.31	565	351	22	103	635	81	606	5e-19	102
rs:WP_019954750	DNA topoisomerase I [Loktanella vestfoldensis].	22.60	655	396	21	38	629	16	622	5e-19	102
rs:WP_043134186	hypothetical protein, partial [Paracoccus sp. 4681].	23.23	663	386	27	77	659	52	671	5e-19	102
rs:WP_026718357	DNA topoisomerase I [Flavobacterium gelidilacus].	24.86	531	329	18	3	521	5	477	5e-19	102
rs:WP_015010243	DNA topoisomerase I [Amphibacillus xylanus].	25.13	565	347	24	103	629	80	606	5e-19	102
rs:WP_021957116	DNA topoisomerase [Eubacterium sp. CAG:115].	24.20	562	371	15	82	616	58	591	5e-19	102
rs:WP_013524908	DNA topoisomerase I [Thermovibrio ammonificans].	24.51	567	346	20	67	603	50	564	5e-19	102
rs:WP_021331401	DNA topoisomerase I [Treponema socranskii].	26.67	510	309	19	163	643	151	624	5e-19	102
rs:WP_043878370	DNA topoisomerase I [Streptococcus infantarius].	23.84	562	352	23	103	630	105	624	5e-19	102
rs:WP_045716599	DNA topoisomerase III, partial [Salmonella enterica].	35.15	165	101	3	420	581	1	162	5e-19	97.1
rs:WP_034054047	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	31.67	180	112	4	1	177	1	172	5e-19	96.3
rs:WP_022417382	DNA topoisomerase [Eubacterium sp. CAG:841].	24.25	565	364	16	83	616	60	591	5e-19	102
rs:WP_035892922	DNA topoisomerase I [Kluyvera ascorbata].	23.74	615	361	26	73	633	74	634	5e-19	102
rs:WP_002088184	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	24.06	561	367	21	105	635	82	613	5e-19	102
rs:WP_031666351	DNA topoisomerase I [Listeria monocytogenes].	23.10	554	367	18	105	629	82	605	5e-19	102
rs:WP_009886426	DNA topoisomerase I [Ferroplasma acidarmanus].	25.42	598	371	23	46	618	43	590	5e-19	102
rs:WP_002300224	DNA topoisomerase I [Streptococcus mutans].	23.67	583	367	23	83	630	78	617	5e-19	102
rs:WP_002262866	DNA topoisomerase I [Streptococcus mutans].	23.67	583	367	23	83	630	78	617	5e-19	102
rs:WP_014918887	DNA topoisomerase I [Lactobacillus helveticus].	24.69	571	351	21	103	635	93	622	5e-19	102
rs:WP_026674294	DNA topoisomerase I [Bacillus bogoriensis].	23.79	559	364	18	103	630	80	607	5e-19	102
rs:WP_024869872	DNA topoisomerase I [Pseudoxanthomonas suwonensis].	26.01	469	292	15	103	538	80	526	5e-19	102
rs:WP_041973403	MULTISPECIES: DNA topoisomerase I [Streptococcus].	22.82	561	359	20	103	630	108	627	5e-19	102
rs:WP_027191454	DNA topoisomerase I [Desulfovibrio putealis].	23.57	645	381	24	1	614	1	564	5e-19	101
rs:NP_001120391	DNA topoisomerase 3-beta-1 isoform 2 [Xenopus (Silurana) tropicalis].	22.82	618	400	21	3	585	5	580	5e-19	102
rs:WP_008220403	topoisomerase I [Rheinheimera nanhaiensis].	24.67	600	364	21	74	631	75	628	5e-19	102
rs:WP_022608758	DNA topoisomerase I [Rubidibacter lacunae].	24.64	625	363	22	2	572	3	573	5e-19	102
tr:A5UT75_ROSS1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.29	687	406	24	2	630	4	627	5e-19	102
rs:WP_012222293	DNA topoisomerase I [Gluconacetobacter diazotrophicus].	22.22	639	404	23	55	630	28	636	5e-19	102
rs:WP_045374699	DNA topoisomerase I [Enterobacter aerogenes].	23.42	619	367	22	60	633	78	634	5e-19	102
rs:WP_033158878	DNA topoisomerase I [Methylomonas sp. LW13].	23.63	601	381	20	76	630	53	621	5e-19	102
tr:L7NK28_PHODP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.97	584	384	15	77	633	90	640	5e-19	102
rs:WP_007069521	DNA topoisomerase I [Dialister invisus].	24.15	646	398	21	3	616	34	619	5e-19	102
rs:WP_024785252	DNA topoisomerase I [Streptococcus mutans].	24.61	581	364	25	83	630	78	617	5e-19	102
rs:WP_019463844	DNA topoisomerase I [Dyella japonica].	24.18	579	343	21	3	538	5	530	5e-19	102
rs:XP_010510117	PREDICTED: DNA topoisomerase 3-beta isoform X3 [Camelina sativa].	24.65	507	323	18	105	586	20	492	5e-19	102
rs:WP_006309612	DNA topoisomerase I [Facklamia languida].	23.82	571	367	21	90	629	68	601	5e-19	101
rs:XP_007054991	PREDICTED: DNA topoisomerase 3-beta-1 [Chelonia mydas].	23.28	610	381	22	3	564	5	575	5e-19	102
rs:WP_017671279	DNA topoisomerase I [Blastomonas sp. AAP53].	23.09	667	422	22	1	629	1	614	5e-19	102
rs:WP_016086606	DNA topoisomerase 1 [Bacillus cereus].	23.57	560	371	20	105	635	82	613	5e-19	101
rs:WP_018632196	hypothetical protein [Meganema perideroedes].	22.39	679	419	27	1	630	1	620	5e-19	102
tr:C2PZI4_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.06	561	367	21	105	635	52	583	5e-19	101
rs:XP_003210910	PREDICTED: DNA topoisomerase 3-beta-1 [Meleagris gallopavo].	22.90	607	387	19	3	564	5	575	5e-19	102
rs:XP_005445283	PREDICTED: DNA topoisomerase 3-beta-1 [Falco cherrug].	22.73	607	388	19	3	564	5	575	5e-19	102
rs:WP_045998281	DNA topoisomerase I [Loktanella sp. S4079].	22.90	703	388	26	1	629	1	623	5e-19	102
rs:WP_037943341	DNA topoisomerase I [Sulfitobacter sp. CB2047].	23.17	630	377	25	1	589	1	564	5e-19	102
rs:WP_034525093	hypothetical protein [Bacteroides propionicifaciens].	33.33	186	106	5	4	178	5	183	5e-19	97.1
tr:S6F3I0_LACLL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.82	556	352	21	103	629	53	571	5e-19	101
rs:WP_026509973	DNA topoisomerase I [Butyrivibrio sp. LC3010].	24.86	555	357	17	90	616	70	592	5e-19	101
rs:WP_017430159	topoisomerase I [Halomonas jeotgali].	24.36	583	368	18	83	633	101	642	5e-19	102
tr:A0A0C6FJ59_9RHIZ	SubName: Full=TopA protein {ECO:0000313|EMBL:BAQ48568.1};	22.00	550	346	19	33	520	35	563	5e-19	102
rs:WP_023392189	DNA topoisomerase I [Abiotrophia defectiva].	24.61	573	359	22	90	629	68	600	5e-19	101
rs:XP_625165	PREDICTED: DNA topoisomerase 3-beta-1-like isoform 2 [Apis mellifera].	21.24	678	447	20	3	630	5	645	5e-19	102
rs:WP_002608927	DNA topoisomerase I [[Clostridium] innocuum].	24.63	536	334	16	3	520	4	487	5e-19	102
rs:WP_009589046	MULTISPECIES: DNA topoisomerase I [Clostridiales].	24.63	536	334	16	3	520	4	487	5e-19	102
rs:WP_045428428	DNA topoisomerase I [Pseudomonas sp. MT-1].	23.75	480	296	11	187	633	194	636	5e-19	102
rs:XP_004518397	PREDICTED: DNA topoisomerase 3-beta [Ceratitis capitata].	25.59	383	248	11	188	560	211	566	5e-19	102
rs:WP_019770716	DNA topoisomerase I [Streptococcus sobrinus].	23.71	582	366	22	83	629	87	625	5e-19	101
rs:WP_019881158	MULTISPECIES: DNA topoisomerase I [Methylophilus].	23.41	662	390	25	2	614	3	596	5e-19	102
rs:WP_021678025	DNA topoisomerase, partial [Porphyromonas gingivalis].	30.74	270	155	9	155	408	2	255	5e-19	98.2
rs:WP_017030849	topoisomerase I [Vibrio breoganii].	23.39	620	369	22	57	633	83	639	5e-19	102
rs:WP_031816604	DNA topoisomerase I [Vibrio parahaemolyticus].	23.77	589	385	17	75	633	9	563	5e-19	102
rs:WP_012679592	DNA topoisomerase I [Streptococcus equi].	23.70	578	373	19	83	630	84	623	5e-19	101
rs:WP_032805444	DNA topoisomerase I [Cronobacter universalis].	24.22	611	363	25	73	633	74	634	5e-19	102
rs:WP_012810735	DNA topoisomerase I [Alicyclobacillus acidocaldarius].	24.32	555	365	18	88	615	62	588	6e-19	101
rs:XP_009909292	PREDICTED: DNA topoisomerase 3-beta-1 [Picoides pubescens].	22.73	607	388	19	3	564	5	575	6e-19	102
rs:WP_010161805	DNA topoisomerase I [Sphingomonas sp. PAMC 26617].	23.41	675	410	27	1	629	1	614	6e-19	102
rs:WP_020770795	DNA topoisomerase I [Leptospira sp. B5-022].	25.90	610	344	23	55	610	28	583	6e-19	101
rs:WP_029739158	DNA topoisomerase I, partial [Cloacimonetes bacterium SCGC AAA252-K16].	27.70	527	310	19	83	577	60	547	6e-19	101
rs:WP_040480579	DNA topoisomerase I [Halomonas boliviensis].	25.08	590	369	20	76	633	94	642	6e-19	102
rs:XP_010579931	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Haliaeetus leucocephalus].	22.73	607	388	19	3	564	5	575	6e-19	102
rs:WP_022398991	GTP-sensing transcriptional pleiotropic repressor CodY [Roseburia sp. CAG:471].	23.73	569	346	20	90	616	67	589	6e-19	101
rs:WP_028013404	DNA topoisomerase I [Enterobacter cloacae].	23.85	587	384	20	76	633	82	634	6e-19	102
rs:WP_006875905	DNA topoisomerase I [Anaerotruncus colihominis].	24.14	638	386	23	90	679	69	656	6e-19	101
rs:WP_015817498	topoisomerase I [Teredinibacter turnerae].	23.47	605	382	19	65	629	80	643	6e-19	102
tr:E6W3Q7_DESIS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.58	653	393	21	2	616	5	589	6e-19	102
tr:Q1H4T9_METFK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.33	674	403	26	2	630	3	614	6e-19	102
rs:XP_008270403	PREDICTED: DNA topoisomerase 3-beta-1 [Oryctolagus cuniculus].	22.54	630	401	20	3	585	5	594	6e-19	102
tr:Q2SD25_HAHCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.13	597	360	21	76	633	106	654	6e-19	102
rs:WP_020033631	hypothetical protein [Oceanospirillales bacterium SCGC AAA298-N10].	25.28	617	347	25	58	629	82	629	6e-19	102
rs:WP_024930446	DNA topoisomerase I [Methylophilus sp. OH31].	23.41	662	390	25	2	614	3	596	6e-19	102
rs:WP_022343868	DNA topoisomerase [Clostridium sp. CAG:356].	24.12	510	336	15	90	574	67	550	6e-19	101
tr:E3YPQ4_9LIST	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.10	554	367	19	105	629	82	605	6e-19	101
rs:WP_036816340	DNA topoisomerase I [Pontibacillus yanchengensis].	23.40	564	368	20	105	635	82	614	6e-19	101
rs:WP_044979619	DNA topoisomerase I [Treponema putidum].	25.35	505	299	20	163	629	157	621	6e-19	101
tr:E6QCJ7_9ZZZZ	SubName: Full=DNA topoisomerase I, plasmid (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) {ECO:0000313|EMBL:CBI04923.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI04923.1};	24.13	572	340	19	1	537	1	513	6e-19	101
rs:WP_035983940	DNA topoisomerase I [Leptospira meyeri].	23.61	538	352	11	87	596	48	554	6e-19	101
rs:WP_006989665	DNA topoisomerase I [Gillisia limnaea].	25.84	534	320	19	3	521	5	477	6e-19	102
tr:K8DBD0_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.22	611	363	25	73	633	88	648	6e-19	102
rs:WP_035411959	DNA topoisomerase I [Bacillus sp. SJS].	23.80	563	365	19	105	635	82	612	6e-19	101
rs:WP_014030375	DNA topoisomerase I [Acidithiobacillus ferrivorans].	22.82	631	392	24	19	611	4	577	6e-19	101
rs:WP_022337852	DNA topoisomerase [Clostridium sp. CAG:433].	22.83	635	406	19	3	614	5	578	6e-19	101
rs:WP_008915752	DNA topoisomerase I subunit omega [Providencia sneebia].	24.23	520	325	13	187	673	192	675	6e-19	102
rs:WP_046198501	DNA topoisomerase I [Bacillus sp. UMTAT18].	23.75	560	370	20	105	635	82	613	6e-19	101
rs:WP_015324220	DNA topoisomerase I, archaeal [Methanomethylovorans hollandica].	22.04	667	437	27	1	630	1	621	6e-19	101
rs:WP_006870710	DNA topoisomerase I [Legionella drancourtii].	24.23	681	398	29	3	630	5	620	6e-19	101
rs:WP_036712476	hypothetical protein, partial [Paracoccus sp. 5503].	23.23	663	386	27	77	659	52	671	6e-19	102
rs:WP_003320692	DNA topoisomerase I [Bacillus alcalophilus].	23.70	557	366	20	103	630	80	606	6e-19	101
rs:WP_003354565	DNA topoisomerase I [Bacillus smithii].	24.78	569	353	22	105	635	82	613	6e-19	101
rs:WP_017864498	DNA topoisomerase I [Lactococcus lactis].	24.28	556	355	20	103	629	103	621	6e-19	101
rs:WP_026711915	DNA topoisomerase I [Flavobacterium filum].	25.66	530	326	18	3	521	5	477	6e-19	102
rs:WP_039579585	DNA topoisomerase I [Xanthomonas axonopodis].	24.26	573	346	20	3	538	5	526	6e-19	102
rs:WP_019468457	DNA topoisomerase I [Staphylococcus sp. AL1].	24.30	568	370	18	90	629	67	602	6e-19	101
tr:K8BYZ7_9ENTR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CCJ97843.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CCJ97843.1};	33.73	166	104	2	457	622	13	172	6e-19	96.3
rs:WP_001286971	DNA topoisomerase I [Bacillus cereus].	23.75	560	370	20	105	635	82	613	6e-19	101
rs:WP_009807374	DNA topoisomerase I [Oceanicola batsensis].	23.17	695	397	26	1	630	1	623	6e-19	102
rs:WP_038212929	DNA topoisomerase I [Vibrio variabilis].	24.06	503	314	14	163	633	173	639	6e-19	102
rs:WP_038192898	DNA topoisomerase I [Vibrio sinaloensis].	24.06	503	314	14	163	633	173	639	6e-19	102
rs:WP_041511027	DNA topoisomerase I [Shewanella sp. cp20].	23.83	600	369	18	74	631	88	641	6e-19	102
rs:WP_037965068	DNA topoisomerase I [Sulfitobacter pontiacus].	23.17	630	377	25	1	589	1	564	6e-19	102
rs:WP_033899618	DNA topoisomerase I [Lactococcus lactis].	24.82	556	352	21	103	629	103	621	6e-19	101
rs:WP_024785984	DNA topoisomerase I [Streptococcus mutans].	23.50	583	368	23	83	630	78	617	6e-19	101
rs:XP_006140260	PREDICTED: DNA topoisomerase 3-beta-1 [Tupaia chinensis].	23.05	629	398	21	3	585	5	593	6e-19	102
rs:WP_022989227	topoisomerase I [Marinobacter sp. ES-1].	23.11	636	408	18	76	673	93	685	6e-19	102
rs:WP_027218029	DNA topoisomerase I [Butyrivibrio fibrisolvens].	25.04	627	389	22	90	679	68	650	6e-19	101
tr:F1KW18_ASCSU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.70	608	379	20	3	560	5	571	6e-19	102
rs:WP_034813314	DNA topoisomerase I [Hyphomonas sp. L-53-1-40].	24.12	684	406	30	1	629	1	626	6e-19	102
rs:WP_036705590	hypothetical protein, partial [Paracoccus sp. 10990].	23.08	663	387	26	77	659	52	671	6e-19	102
rs:WP_028243884	DNA topoisomerase I [Pseudobutyrivibrio ruminis].	23.65	613	392	21	36	616	22	590	6e-19	101
rs:XP_011860627	PREDICTED: DNA topoisomerase 3-beta-1 [Vollenhovia emeryi].	21.84	673	449	18	3	630	5	645	7e-19	102
tr:G7JBC7_MEDTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.79	667	438	20	3	631	7	634	7e-19	102
rs:WP_022331603	DNA topoisomerase [Firmicutes bacterium CAG:345].	24.22	669	395	24	1	630	1	596	7e-19	101
rs:WP_026692501	DNA topoisomerase I [Bacillus kribbensis].	24.46	560	352	20	105	629	82	605	7e-19	101
rs:WP_015639701	DNA topoisomerase, partial [Lactobacillus plantarum].	29.76	252	147	8	167	396	13	256	7e-19	97.8
rs:WP_045186733	DNA topoisomerase I [Pseudomonas sp. 5].	24.11	593	377	21	74	633	87	639	7e-19	102
rs:WP_037468625	DNA topoisomerase I [Sphingobium herbicidovorans].	21.69	724	463	25	1	680	1	664	7e-19	101
rs:WP_002309563	DNA topoisomerase I [Streptococcus mutans].	23.67	583	367	23	83	630	78	617	7e-19	101
rs:WP_016192569	DNA topoisomerase I subunit omega [Erwinia tracheiphila].	22.24	661	404	18	58	673	78	673	7e-19	102
rs:WP_024783479	DNA topoisomerase I [Streptococcus mutans].	23.67	583	367	23	83	630	78	617	7e-19	101
rs:WP_022350694	GTP-sensing transcriptional pleiotropic repressor CodY [Firmicutes bacterium CAG:534].	25.13	557	352	20	90	616	67	588	7e-19	101
rs:WP_024723336	DNA topoisomerase I [Clostridiales bacterium VE202-03].	22.99	561	373	17	83	614	61	591	7e-19	101
rs:WP_036938706	DNA topoisomerase I [Pseudobacteroides cellulosolvens].	24.52	571	340	22	90	616	67	590	7e-19	101
rs:WP_028394567	DNA topoisomerase I [Bacillus sp. FJAT-14578].	24.25	569	356	22	105	635	82	613	7e-19	101
rs:WP_036087905	DNA topoisomerase I [Leptotrichia hofstadii].	23.66	617	378	19	2	589	4	556	7e-19	101
rs:WP_035552266	DNA topoisomerase I [Hyphomonas atlantica].	23.98	684	407	29	1	629	1	626	7e-19	101
tr:G2KTQ4_LACSM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.90	590	376	21	79	629	40	595	7e-19	101
rs:WP_039631942	DNA topoisomerase I [Clostridium argentinense].	25.96	547	334	18	103	616	80	588	7e-19	101
rs:WP_017380848	DNA topoisomerase I [Paenisporosarcina sp. TG-14].	25.99	558	346	25	105	629	82	605	7e-19	101
rs:WP_031851619	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	7e-19	101
rs:WP_046492712	DNA topoisomerase I [Flavobacteriaceae bacterium ASP10-09a].	25.56	532	324	17	3	521	5	477	7e-19	101
rs:WP_026601896	DNA topoisomerase I [Methylomonas sp. 11b].	23.09	602	383	20	76	630	53	621	7e-19	101
rs:XP_012632163	PREDICTED: DNA topoisomerase 3-beta-1 [Microcebus murinus].	22.98	631	396	22	3	585	5	593	7e-19	101
rs:WP_020210395	topoisomerase I [Gilvimarinus chinensis].	24.51	612	364	26	57	629	88	640	7e-19	101
rs:WP_045082622	MULTISPECIES: DNA topoisomerase I [Photobacterium].	24.79	597	373	21	73	633	83	639	7e-19	101
rs:WP_045149582	DNA topoisomerase I [Photobacterium angustum].	24.79	597	373	21	73	633	83	639	7e-19	101
rs:WP_006647016	topoisomerase I [Photobacterium sp. SKA34].	24.79	597	373	21	73	633	83	639	7e-19	101
rs:WP_008336478	DNA topoisomerase I [Alicyclobacillus acidocaldarius].	24.14	555	366	18	88	615	62	588	7e-19	101
rs:WP_025295581	DNA topoisomerase I [Sphingomonas sanxanigenens].	23.65	668	417	28	1	629	1	614	7e-19	101
rs:WP_020504206	DNA topoisomerase I [Lamprocystis purpurea].	22.27	696	435	26	1	649	1	637	7e-19	101
tr:K1U5H1_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC77523.1}; Flags: Fragment;	32.22	180	105	5	2	174	3	172	7e-19	95.9
rs:WP_005370813	topoisomerase I [Photobacterium angustum].	24.79	597	373	21	73	633	83	639	7e-19	101
rs:WP_010943185	DNA topoisomerase I [Geobacter sulfurreducens].	23.14	713	433	25	3	658	5	659	7e-19	101
tr:G4VFA7_SCHMA	SubName: Full=Putative prokaryotic DNA topoisomerase {ECO:0000313|EMBL:CCD78615.1};	23.79	597	389	22	3	566	319	882	7e-19	102
rs:WP_004850155	MULTISPECIES: topoisomerase I [Klebsiella].	23.19	621	366	22	60	633	78	634	7e-19	101
rs:WP_015280197	DNA topoisomerase I [Thioflavicoccus mobilis].	23.36	685	408	28	1	630	1	623	7e-19	101
rs:WP_005470465	topoisomerase I [Vibrio sp. 16].	24.06	503	314	14	163	633	173	639	7e-19	101
rs:WP_036764082	DNA topoisomerase I [Photobacterium damselae].	23.97	584	384	15	77	633	90	640	7e-19	101
rs:WP_019795444	DNA topoisomerase I [Streptococcus sobrinus].	23.54	582	367	22	83	629	87	625	7e-19	101
gpu:CP009498_962	DNA topoisomerase 1 [Candidatus Endomicrobium sp. Rsa215]	25.29	597	356	21	90	640	67	619	7e-19	101
rs:WP_021444458	hypothetical protein, partial [Pseudomonas sp. EGD-AK9].	30.69	189	114	4	1	179	1	182	7e-19	96.3
rs:WP_025639521	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	7e-19	101
rs:WP_028452852	DNA topoisomerase I [Chitinilyticum aquatile].	23.33	673	408	22	3	630	5	614	7e-19	101
rs:WP_023839464	DNA topoisomerase I [Blastomonas sp. CACIA14H2].	23.32	669	418	23	1	629	1	614	7e-19	101
rs:WP_009826132	DNA topoisomerase I [Sulfitobacter sp. NAS-14.1].	23.17	630	377	25	1	589	1	564	7e-19	101
rs:WP_032807398	DNA topoisomerase I [Cronobacter turicensis].	23.59	602	378	21	73	633	74	634	7e-19	101
rs:WP_038805147	DNA topoisomerase I, partial [Salmonella enterica].	23.87	595	385	20	73	633	74	634	7e-19	101
tr:A0A081EW32_9EURY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.66	452	267	20	2	412	6	429	7e-19	99.8
rs:WP_028124627	DNA topoisomerase I [Eremococcus coleocola].	25.52	576	349	21	90	629	68	599	7e-19	101
rs:WP_033539235	DNA topoisomerase I [Shewanella sp. ECSMB14101].	24.17	600	367	19	74	631	88	641	7e-19	101
rs:WP_018360551	hypothetical protein [Porphyromonas macacae].	24.91	542	328	21	3	525	5	486	7e-19	101
tr:C2PIZ8_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.75	560	370	20	105	635	75	606	7e-19	101
rs:WP_003480796	DNA topoisomerase I [Xanthomonas translucens].	23.11	688	416	25	3	638	5	631	7e-19	101
tr:C3DNN3_BACTS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.83	533	348	20	154	655	22	527	7e-19	100
rs:WP_008817324	MULTISPECIES: DNA topoisomerase I [Erysipelotrichaceae].	24.63	536	334	16	3	520	4	487	7e-19	101
rs:WP_012017586	topoisomerase I [Enterobacter sp. 638].	23.18	604	378	22	73	633	74	634	7e-19	101
rs:WP_011815111	DNA topoisomerase I [Halorhodospira halophila].	22.88	590	352	21	3	538	5	545	7e-19	101
rs:XP_011172547	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Solenopsis invicta].	23.01	465	313	11	185	630	152	590	7e-19	101
rs:WP_034675695	DNA topoisomerase I [Bacillus niacini].	23.01	552	372	17	105	629	82	607	8e-19	101
rs:WP_011752551	DNA topoisomerase [Thermofilum pendens].	22.68	613	399	21	3	579	6	579	8e-19	101
rs:XP_006640211	PREDICTED: DNA topoisomerase 3-beta-1-like [Lepisosteus oculatus].	23.26	632	393	23	3	585	5	593	8e-19	101
rs:WP_014600791	DNA topoisomerase I [Listeria monocytogenes].	23.10	554	367	18	105	629	82	605	8e-19	101
rs:XP_005391746	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Chinchilla lanigera].	22.82	631	397	21	3	585	5	593	8e-19	101
rs:WP_021968589	DNA topoisomerase [Mycoplasma sp. CAG:956].	24.69	733	404	29	3	658	7	668	8e-19	101
rs:WP_015955838	DNA topoisomerase I [Cyanothece sp. PCC 7424].	24.08	573	352	17	90	615	72	608	8e-19	101
rs:WP_018718076	DNA topoisomerase I [Arhodomonas aquaeolei].	23.83	579	342	22	2	538	4	525	8e-19	101
rs:WP_023184162	DNA topoisomerase I subunit omega [Salmonella enterica].	24.03	595	384	20	73	633	74	634	8e-19	101
rs:WP_002583384	MULTISPECIES: DNA topoisomerase I [Clostridiales].	23.90	569	350	19	90	616	67	594	8e-19	101
rs:WP_036301804	DNA topoisomerase I [Methylotenera sp. L2L1].	24.39	660	384	25	2	614	3	594	8e-19	101
tr:D0YYM1_LISDA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.97	584	384	15	77	633	60	610	8e-19	101
rs:WP_009463185	DNA topoisomerase I [Ahrensia sp. R2A130].	23.08	702	395	28	1	629	1	630	8e-19	101
rs:WP_036736860	hypothetical protein, partial [Paracoccus sp. 39524].	23.08	663	387	26	77	659	52	671	8e-19	101
rs:WP_025242302	DNA topoisomerase I [Pseudomonas stutzeri].	23.06	594	382	15	74	633	84	636	8e-19	101
rs:WP_005851683	DNA topoisomerase I [Sulfitobacter sp. EE-36].	23.17	630	377	25	1	589	1	564	8e-19	101
rs:WP_020615298	DNA topoisomerase I [Paenibacillus daejeonensis].	23.63	584	381	21	88	636	62	615	8e-19	101
rs:WP_039677107	DNA topoisomerase I [Streptococcus constellatus].	23.65	575	374	20	83	629	70	607	8e-19	101
rs:WP_023488722	DNA topoisomerase [Lactobacillus crispatus].	24.56	570	353	21	103	635	92	621	8e-19	101
rs:WP_040017644	DNA topoisomerase I [Enterobacter ludwigii].	23.56	607	361	21	76	633	82	634	8e-19	101
rs:WP_004096816	DNA topoisomerase I [Acetonema longum].	24.02	562	361	18	88	616	62	590	8e-19	101
tr:A0A090RLB9_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.05	499	319	14	163	633	56	522	8e-19	100
rs:WP_027915088	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	24.16	476	301	14	186	633	195	638	8e-19	101
rs:WP_018066740	DNA topoisomerase I [Martelella mediterranea].	22.95	706	398	30	1	630	1	636	8e-19	101
rs:WP_002540185	DNA topoisomerase I [Grimontia indica].	24.42	606	360	21	74	633	86	639	8e-19	101
rs:WP_027149269	DNA topoisomerase I [Methylobacter tundripaludum].	24.39	574	335	22	3	534	5	521	8e-19	101
rs:WP_037107832	DNA topoisomerase I [Rhizobium sp. OK665].	23.44	691	413	28	1	630	1	636	8e-19	101
rs:WP_006892984	DNA topoisomerase I [Methylobacter tundripaludum].	24.39	574	335	22	3	534	5	521	8e-19	101
tr:X0ZSC2_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_C01715 {ECO:0000313|EMBL:GAG72680.1}; Flags: Fragment;	26.53	441	288	18	1	420	1	426	8e-19	99.8
rs:WP_003470405	DNA topoisomerase I [Xanthomonas translucens].	23.11	688	416	25	3	638	5	631	8e-19	101
rs:WP_010920309	DNA topoisomerase I [Caulobacter vibrioides].	22.34	685	417	24	1	629	1	626	8e-19	101
rs:WP_009304728	MULTISPECIES: DNA topoisomerase [Eggerthella].	23.69	553	357	22	90	616	135	648	8e-19	101
rs:WP_019805740	DNA topoisomerase I [Streptococcus mutans].	23.67	583	367	23	83	630	78	617	8e-19	101
rs:WP_028713422	DNA topoisomerase I [Paracoccus sp. J55].	22.90	690	403	26	1	630	1	621	8e-19	101
rs:WP_029795501	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	8e-19	101
rs:WP_025818118	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	8e-19	101
rs:WP_045161401	DNA topoisomerase I [Salmonella enterica].	23.87	595	385	20	73	633	74	634	8e-19	101
rs:WP_019786482	DNA topoisomerase I, partial [Streptococcus sobrinus].	23.54	582	367	22	83	629	87	625	8e-19	100
rs:WP_002362367	DNA topoisomerase, partial [Enterococcus faecium].	25.68	366	239	7	130	471	1	357	8e-19	98.6
rs:WP_019553209	hypothetical protein [Propionispira raffinosivorans].	23.57	645	401	23	3	616	9	592	8e-19	101
rs:WP_024226552	hypothetical protein, partial [Escherichia coli].	33.74	243	144	6	348	574	30	271	8e-19	97.8
rs:WP_010219084	DNA topoisomerase I [Sphingomonas sp. PAMC 26621].	23.41	675	410	27	1	629	1	614	8e-19	101
rs:WP_022500236	DNA topoisomerase [Firmicutes bacterium CAG:95].	24.78	561	350	19	90	616	67	589	8e-19	101
rs:WP_021888524	DNA topoisomerase [Firmicutes bacterium CAG:110].	23.91	594	377	24	88	640	64	623	8e-19	101
rs:WP_034820062	DNA topoisomerase I [Idiomarina sp. 28-8].	24.33	485	282	16	187	629	196	637	8e-19	101
rs:WP_010412954	DNA topoisomerase I [Citromicrobium sp. JLT1363].	23.37	659	408	22	1	619	1	602	8e-19	101
rs:WP_008491745	DNA topoisomerase I [SAR86 cluster bacterium SAR86E].	24.00	700	387	25	3	629	5	632	8e-19	101
rs:WP_012581412	DNA topoisomerase I [Listeria monocytogenes].	23.10	554	367	19	105	629	82	605	9e-19	101
rs:WP_002267968	DNA topoisomerase I [Streptococcus mutans].	23.67	583	367	23	83	630	78	617	9e-19	101
rs:WP_004578652	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	23.87	595	385	20	73	633	74	634	9e-19	101
rs:WP_009987542	DNA topoisomerase III [Ruminococcus flavefaciens].	27.49	331	205	11	1	303	1	324	9e-19	98.2
rs:WP_034872881	DNA topoisomerase I [Endozoicomonas montiporae].	24.92	610	368	25	65	631	80	642	9e-19	101
tr:A0A0A5IXC3_CITKO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.79	597	383	20	73	633	74	634	9e-19	101
rs:WP_008226122	DNA topoisomerase I [Roseobacter sp. GAI101].	23.16	570	339	20	1	534	1	507	9e-19	101
rs:WP_043635602	DNA topoisomerase I [Chromobacterium haemolyticum].	22.94	667	416	22	3	630	5	612	9e-19	101
rs:WP_039693667	DNA topoisomerase I [Streptococcus gallolyticus].	22.82	561	359	20	103	630	106	625	9e-19	101
rs:WP_019413034	DNA topoisomerase I [Paenisporosarcina sp. TG20].	25.18	560	348	22	105	629	82	605	9e-19	101
rs:WP_007749548	DNA topoisomerase I [Cronobacter dublinensis].	24.26	606	369	22	73	633	4	564	9e-19	101
rs:WP_043959647	DNA topoisomerase I [Lysobacter sp. A03].	24.09	494	303	14	85	536	62	525	9e-19	101
rs:WP_034773800	DNA topoisomerase I [Idiomarina salinarum].	23.79	601	372	19	74	633	86	641	9e-19	101
rs:WP_013669135	DNA topoisomerase I [Aerococcus urinae].	25.78	574	351	23	90	629	75	607	9e-19	101
rs:WP_007476321	DNA topoisomerase I [Listeria fleischmannii].	24.47	568	356	23	105	635	82	613	9e-19	101
rs:XP_006661399	PREDICTED: DNA topoisomerase 3-beta-1-like [Oryza brachyantha].	22.48	565	362	21	54	586	181	701	9e-19	101
rs:WP_004861033	MULTISPECIES: topoisomerase I [Enterobacteriaceae].	23.62	597	384	19	73	633	74	634	9e-19	101
tr:E3ZYQ7_LISSE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.10	554	367	19	105	629	82	605	9e-19	100
rs:WP_015845040	DNA topoisomerase I [Paenibacillus sp. JDR-2].	23.59	585	380	22	88	636	62	615	9e-19	101
rs:WP_038395914	DNA topoisomerase I [Salmonella enterica].	23.87	595	385	20	73	633	74	634	9e-19	101
rs:WP_043098176	DNA topoisomerase I, partial [bacterium JKG1].	23.19	608	377	20	76	630	53	623	9e-19	101
rs:WP_019776889	DNA topoisomerase I [Streptococcus sobrinus].	23.54	582	367	22	83	629	87	625	9e-19	101
rs:WP_022756508	DNA topoisomerase I [Butyrivibrio fibrisolvens].	25.04	627	389	22	90	679	68	650	9e-19	100
rs:WP_006955122	topoisomerase I [Idiomarina baltica].	24.17	600	359	21	76	629	88	637	9e-19	101
rs:WP_023207743	DNA topoisomerase 1 [Salmonella enterica].	24.03	595	384	20	73	633	74	634	9e-19	101
rs:WP_002507864	MULTISPECIES: DNA topoisomerase I [Staphylococcus].	24.10	556	367	17	100	629	77	603	9e-19	100
tr:A0A090LMM2_STRRB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.69	661	413	24	3	612	5	618	9e-19	101
tr:K8B7C3_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.59	602	378	21	73	633	88	648	9e-19	101
rs:XP_008115565	PREDICTED: DNA topoisomerase 3-beta-1 [Anolis carolinensis].	22.68	613	381	21	3	564	5	575	9e-19	101
rs:WP_023213660	DNA topoisomerase I subunit omega [Salmonella enterica].	23.87	595	385	20	73	633	74	634	9e-19	101
rs:WP_013257954	DNA topoisomerase I [Desulfarculus baarsii].	21.84	673	426	21	3	631	5	621	9e-19	101
rs:WP_027216148	DNA topoisomerase I [Butyrivibrio fibrisolvens].	25.04	627	389	22	90	679	68	650	9e-19	100
rs:WP_003484458	DNA topoisomerase I [Xanthomonas citri].	24.26	573	346	20	3	538	5	526	9e-19	101
rs:WP_028294382	DNA topoisomerase I [Oceanobacter kriegii].	24.19	587	372	19	74	629	91	635	9e-19	101
rs:WP_042283444	DNA topoisomerase I [Citrobacter sedlakii].	23.79	597	383	20	73	633	74	634	9e-19	101
rs:WP_023211986	DNA topoisomerase I subunit omega [Salmonella enterica].	23.87	595	385	20	73	633	74	634	9e-19	101
rs:WP_014231327	MULTISPECIES: topoisomerase I [Vibrio].	24.42	602	365	19	75	633	85	639	9e-19	101
rs:WP_011412723	topoisomerase I [Aster yellows witches'-broom phytoplasma].	23.85	608	399	17	88	673	65	630	9e-19	100
rs:WP_047012081	DNA topoisomerase I [Spongiibacter sp. IMCC21906].	24.75	598	364	23	76	633	95	646	9e-19	101
rs:WP_020073187	DNA topoisomerase I [[Clostridium] sporosphaeroides].	23.11	649	404	21	2	616	3	590	9e-19	100
rs:WP_040185591	DNA topoisomerase III, partial [Klebsiella pneumoniae].	29.52	315	192	9	381	673	2	308	1e-18	98.2
rs:WP_036872829	DNA topoisomerase I [Porphyromonas macacae].	24.91	538	325	21	3	521	5	482	1e-18	101
rs:WP_045976753	DNA topoisomerase I [Vibrio neptunius].	24.80	500	314	12	163	633	173	639	1e-18	101
rs:WP_031571001	DNA topoisomerase I [Rheinheimera texasensis].	24.41	680	408	27	3	631	5	629	1e-18	101
rs:WP_041331875	DNA topoisomerase I, partial [Roseiflexus castenholzii].	22.80	658	405	19	2	610	4	607	1e-18	101
rs:WP_002286698	DNA topoisomerase I [Streptococcus mutans].	23.71	582	368	23	83	630	78	617	1e-18	100
rs:WP_035040032	DNA topoisomerase I [Catonella morbi].	23.85	566	348	20	90	616	67	588	1e-18	100
rs:WP_026979520	DNA topoisomerase I [Flavobacterium suncheonense].	25.14	529	330	15	3	521	5	477	1e-18	101
rs:WP_015606150	DNA topoisomerase I [Salmonella enterica].	23.87	595	385	20	73	633	74	634	1e-18	101
rs:WP_046465282	DNA topoisomerase I [Staphylococcus equorum].	24.28	556	366	18	100	629	77	603	1e-18	100
rs:WP_038138899	DNA topoisomerase I [Vibrio caribbeanicus].	24.06	503	314	14	163	633	173	639	1e-18	101
rs:WP_027853634	DNA topoisomerase I [Marinobacterium litorale].	23.50	600	372	20	75	633	90	643	1e-18	101
rs:WP_025392403	DNA topoisomerase I [Desulfurella acetivorans].	23.31	708	430	22	1	669	2	635	1e-18	100
rs:WP_018210926	DNA topoisomerase I [Desulfitobacterium hafniense].	22.71	709	435	27	3	671	5	640	1e-18	100
rs:WP_029827738	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	1e-18	100
rs:WP_019899838	DNA topoisomerase I [Methylotenera mobilis].	25.11	657	383	25	2	614	3	594	1e-18	101
rs:WP_000513597	topoisomerase I [Salmonella enterica].	23.87	595	385	20	73	633	74	634	1e-18	101
rs:WP_023458044	DNA topoisomerase I [Asticcacaulis sp. AC466].	22.38	621	415	17	55	629	27	626	1e-18	101
rs:WP_013331964	topoisomerase I [Halomonas elongata].	25.47	483	283	17	186	631	201	643	1e-18	101
rs:WP_023534198	DNA topoisomerase I [Pseudomonas putida].	24.16	476	301	14	186	633	195	638	1e-18	101
rs:WP_029838722	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	1e-18	101
rs:WP_034613184	DNA topoisomerase I [Chelonobacter oris].	23.95	476	302	14	187	633	196	640	1e-18	101
rs:WP_043623982	DNA topoisomerase I [Chromobacterium piscinae].	23.51	604	391	18	70	630	37	612	1e-18	101
rs:WP_029837348	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	1e-18	101
rs:WP_025587383	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	1e-18	101
tr:A0A068X7F0_HYMMI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.66	486	311	12	177	621	195	661	1e-18	101
rs:WP_032111009	DNA topoisomerase [bacterium OL-1].	22.78	474	301	16	186	631	236	672	1e-18	101
tr:S2J5T0_MUCC1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.32	672	446	20	3	631	7	645	1e-18	101
rs:WP_026882308	DNA topoisomerase I [Clostridium akagii].	25.00	652	383	25	3	616	5	588	1e-18	100
rs:WP_029851655	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	1e-18	101
rs:WP_022754505	DNA topoisomerase I [Butyrivibrio fibrisolvens].	25.04	627	389	22	90	679	68	650	1e-18	100
rs:WP_046316504	DNA topoisomerase I [Lactobacillus mellifer].	24.44	577	376	20	83	629	79	625	1e-18	100
rs:WP_003747402	DNA topoisomerase I [Listeria seeligeri].	23.10	554	367	18	105	629	82	605	1e-18	100
rs:WP_036921705	DNA topoisomerase I [Prevotella sp. ICM33].	24.34	608	354	22	3	578	5	538	1e-18	100
rs:WP_038887553	DNA topoisomerase I [Cronobacter dublinensis].	24.26	606	369	22	73	633	74	634	1e-18	101
rs:WP_037555477	DNA topoisomerase I [Staphylococcus sp. URHA0057].	24.46	556	359	20	103	629	80	603	1e-18	100
rs:WP_020840336	topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	1e-18	101
rs:WP_031813486	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	1e-18	101
rs:WP_002146094	DNA topoisomerase I [Bacillus cereus].	24.11	564	363	21	105	635	82	613	1e-18	100
rs:WP_002836341	DNA topoisomerase I [Finegoldia magna].	23.85	650	391	25	2	616	5	585	1e-18	100
rs:WP_025577951	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	1e-18	101
rs:WP_011200271	topoisomerase I [[Mannheimia] succiniciproducens].	24.58	472	304	11	187	633	196	640	1e-18	101
rs:WP_039478450	DNA topoisomerase I [Vibrio sinaloensis].	23.84	495	325	12	163	633	173	639	1e-18	101
rs:WP_002285804	DNA topoisomerase I [Streptococcus mutans].	23.50	583	368	23	83	630	78	617	1e-18	100
rs:WP_009267877	MULTISPECIES: DNA topoisomerase I [Lachnospiraceae].	24.19	558	357	19	90	616	67	589	1e-18	100
tr:A0A0E1XFF3_STRGY	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EFM29549.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFM29549.1};	22.64	561	360	20	103	630	144	663	1e-18	100
rs:WP_028692739	DNA topoisomerase I [Pseudomonas mosselii].	23.84	474	305	12	186	633	195	638	1e-18	101
rs:NP_001031463	DNA topoisomerase, type IA, core [Arabidopsis thaliana].	23.52	506	330	15	105	586	89	561	1e-18	101
tr:G6DFU9_DANPL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.40	715	461	26	3	655	5	680	1e-18	101
rs:WP_021735919	DNA topoisomerase I [Coriobacteriaceae bacterium BV3Ac1].	23.04	560	373	19	87	620	134	661	1e-18	101
rs:WP_025532763	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	1e-18	101
rs:WP_019313223	DNA topoisomerase I [Streptococcus mutans].	23.50	583	368	23	83	630	78	617	1e-18	100
tr:U2ILG3_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.54	582	367	22	83	629	89	627	1e-18	100
rs:WP_017942609	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	23.73	569	344	20	3	534	5	520	1e-18	101
rs:WP_028716244	DNA topoisomerase I [Paracoccus sp. J39].	22.90	690	403	26	1	630	1	621	1e-18	101
rs:WP_027205784	DNA topoisomerase I [Butyrivibrio fibrisolvens].	25.04	627	389	22	90	679	68	650	1e-18	100
rs:WP_036783079	DNA topoisomerase I [Polaribacter sp. Hel1_33_49].	25.93	536	317	20	3	521	5	477	1e-18	101
rs:WP_001527825	topoisomerase I [Salmonella enterica].	23.87	595	385	20	73	633	74	634	1e-18	101
rs:WP_035383427	DNA topoisomerase I, partial [Ferriphaselus sp. R-1].	24.00	575	356	21	100	630	77	614	1e-18	100
tr:E7FNV6_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.53	587	371	21	90	642	87	635	1e-18	100
rs:WP_008858871	DNA topoisomerase I [Dialister succinatiphilus].	24.37	595	360	23	82	629	88	639	1e-18	100
rs:WP_003698300	DNA topoisomerase I [Lactobacillus ruminis].	23.89	586	376	19	90	642	60	608	1e-18	100
rs:WP_007287285	DNA topoisomerase I [Intestinibacter bartlettii].	25.13	569	338	23	103	629	81	603	1e-18	100
rs:WP_036850036	DNA topoisomerase I [Porphyromonas macacae].	25.23	539	322	22	3	521	5	482	1e-18	100
tr:A9MQ04_SALAR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.87	595	385	20	73	633	74	634	1e-18	101
rs:WP_018364712	DNA topoisomerase I [Streptococcus caballi].	24.48	580	365	23	83	630	86	624	1e-18	100
rs:WP_006986741	DNA topoisomerase I [Cardiobacterium valvarum].	24.35	575	324	19	3	534	5	511	1e-18	100
rs:WP_014570604	DNA topoisomerase 1 [Lactococcus lactis].	24.28	556	355	20	103	629	103	621	1e-18	100
rs:WP_001286970	DNA topoisomerase I [Bacillus cereus].	23.57	560	371	20	105	635	82	613	1e-18	100
rs:WP_046923200	DNA topoisomerase I [Lactobacillus ruminis].	24.41	590	368	22	90	642	87	635	1e-18	100
rs:WP_022023449	DNA topoisomerase [Acinetobacter sp. CAG:196].	24.67	673	403	24	3	636	19	626	1e-18	100
rs:WP_025794756	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	1e-18	101
gpu:CP011832_1130	DNA topoisomerase 1 [Geobacillus sp. 12AMOR1]	24.60	504	321	18	157	630	132	606	1e-18	100
sp:TOP1_LACLA	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.28	556	355	20	103	629	103	621	1e-18	100
rs:WP_022319904	DNA topoisomerase [Clostridium sp. CAG:349].	23.07	685	403	24	3	629	5	623	1e-18	100
rs:WP_044803582	DNA topoisomerase III, partial [Bacillus amyloliquefaciens].	33.33	174	107	5	3	173	7	174	1e-18	95.1
rs:WP_000513595	DNA topoisomerase 1 [Salmonella enterica].	23.87	595	385	20	73	633	74	634	1e-18	101
tr:V2XKU8_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.85	566	348	20	90	616	69	590	1e-18	100
rs:WP_029861698	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	1e-18	101
rs:WP_025005757	DNA topoisomerase I [Lactobacillus gallinarum].	23.99	567	360	20	103	635	93	622	1e-18	100
rs:WP_015964649	DNA topoisomerase I [Enterobacteriaceae bacterium strain FGI 57].	23.57	611	360	22	74	633	80	634	1e-18	100
rs:WP_009723521	topoisomerase I [Halomonas sp. TD01].	25.25	598	358	20	76	633	94	642	1e-18	101
rs:WP_013643118	DNA topoisomerase I [Streptococcus gallolyticus].	22.64	561	360	20	103	630	106	625	1e-18	100
rs:WP_020744912	DNA topoisomerase I subunit omega [Alteromonas macleodii].	25.65	612	360	26	65	629	75	638	1e-18	101
tr:W5M1X9_LEPOC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.26	632	393	23	3	585	5	593	1e-18	100
rs:WP_040873068	DNA topoisomerase I, partial [delta proteobacterium NaphS2].	24.46	601	374	21	83	640	60	623	1e-18	100
rs:XP_011298257	PREDICTED: DNA topoisomerase 3-beta-1 [Fopius arisanus].	23.39	466	304	11	188	630	210	645	1e-18	100
rs:WP_023567308	DNA topoisomerase III, partial [Escherichia coli].	34.55	165	102	3	420	581	1	162	1e-18	95.9
rs:WP_014464133	DNA topoisomerase I [Alicyclobacillus acidocaldarius].	24.14	555	366	18	88	615	62	588	1e-18	100
rs:WP_035340555	DNA topoisomerase I [Bacillus hemicellulosilyticus].	24.51	559	357	23	103	629	80	605	1e-18	100
rs:WP_045230664	DNA topoisomerase I [Agrobacterium rubi].	23.95	668	386	26	38	630	16	636	1e-18	101
rs:WP_015457551	DNA topoisomerase I subunit omega [Sphingomonas sp. MM-1].	21.75	722	456	23	1	675	1	660	1e-18	100
rs:WP_000513594	topoisomerase I [Salmonella enterica].	23.87	595	385	20	73	633	74	634	1e-18	100
rs:WP_023234051	DNA topoisomerase I subunit omega [Salmonella enterica].	23.87	595	385	20	73	633	74	634	1e-18	100
rs:WP_022280660	DNA topoisomerase [Lactobacillus ruminis CAG:367].	24.53	587	371	21	90	642	87	635	1e-18	100
rs:WP_021616225	DNA topoisomerase I [Aggregatibacter sp. oral taxon 458].	24.71	595	373	21	74	633	86	640	1e-18	100
tr:W6UHW2_ECHGR	SubName: Full=DNA topoisomerase 3-beta-1 {ECO:0000313|EMBL:EUB60643.1};	22.58	691	422	27	4	629	1	643	1e-18	100
rs:WP_005813282	DNA topoisomerase I [Desulfitobacterium hafniense].	22.71	709	435	27	3	671	5	640	1e-18	100
rs:WP_012985514	DNA topoisomerase I [Listeria seeligeri].	23.10	554	367	19	105	629	82	605	1e-18	100
rs:WP_022234894	DNA topoisomerase [Eubacterium sp. CAG:202].	23.97	580	361	17	76	616	52	590	1e-18	100
rs:WP_039991082	DNA topoisomerase I [Fusobacterium gonidiaformans].	25.61	613	351	20	3	581	6	547	1e-18	100
tr:B8CN12_SHEPW	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.90	611	359	23	74	633	104	659	1e-18	100
rs:WP_035428063	MULTISPECIES: topoisomerase I, partial [Lactobacillus].	29.76	252	147	8	167	396	4	247	1e-18	96.7
rs:WP_016506808	DNA topoisomerase 1 [Salmonella enterica].	23.87	595	385	20	73	633	74	634	1e-18	100
rs:WP_003693908	DNA topoisomerase I [Lactobacillus ruminis].	23.89	586	376	19	90	642	60	608	1e-18	100
rs:WP_005758915	topoisomerase I [Pasteurella bettyae].	24.42	471	306	10	187	633	196	640	1e-18	100
rs:XP_011443037	PREDICTED: DNA topoisomerase 3-beta-1-like [Crassostrea gigas].	22.39	670	447	22	3	630	5	643	1e-18	100
rs:WP_021317628	DNA topoisomerase I [Sphingobium ummariense].	21.49	670	429	20	1	629	1	614	1e-18	100
rs:WP_039503944	DNA topoisomerase I [Salmonella enterica].	23.57	594	388	19	73	633	74	634	1e-18	100
tr:R9PPJ5_AGAAL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.19	608	365	22	74	633	48	601	1e-18	100
rs:WP_024859995	DNA topoisomerase I [Ruminococcus flavefaciens].	24.56	562	352	18	90	616	66	590	1e-18	100
rs:WP_022240234	DNA topoisomerase [Clostridium sp. CAG:413].	25.18	560	340	23	97	616	73	593	1e-18	100
rs:XP_005966779	PREDICTED: DNA topoisomerase 3-alpha-like [Pantholops hodgsonii].	22.84	705	400	28	1	630	1	636	1e-18	100
rs:WP_023189256	DNA topoisomerase 1 [Lactococcus lactis].	24.28	556	355	20	103	629	103	621	1e-18	100
rs:WP_015426411	DNA topoisomerase I [Lactococcus lactis].	24.28	556	355	20	103	629	103	621	1e-18	100
rs:WP_044617686	DNA topoisomerase I [Gynuella sunshinyii].	23.79	601	363	20	76	633	93	641	1e-18	100
rs:WP_013096367	DNA topoisomerase I [Enterobacter cloacae].	23.92	602	365	22	76	633	82	634	1e-18	100
rs:WP_027398235	DNA topoisomerase I [Anaerovorax odorimutans].	25.26	570	341	22	103	629	81	608	1e-18	100
rs:WP_028257373	DNA topoisomerase I [Veillonella montpellierensis].	23.56	573	369	22	90	629	135	671	1e-18	100
rs:WP_021228023	DNA topoisomerase I [Sphingobium lactosutens].	21.71	677	419	23	1	629	1	614	1e-18	100
rs:WP_023212465	DNA topoisomerase I subunit omega [Salmonella enterica].	23.87	595	385	20	73	633	74	634	1e-18	100
rs:WP_023138314	DNA topoisomerase I [Salmonella enterica].	23.12	640	413	22	73	673	74	673	1e-18	100
rs:WP_046623771	DNA topoisomerase I [Salmonella enterica].	23.87	595	385	20	73	633	74	634	1e-18	100
rs:WP_017638385	DNA topoisomerase I [Staphylococcus sp. E463].	24.28	556	360	19	103	629	80	603	1e-18	100
rs:WP_017914936	DNA topoisomerase I [Xanthomonas sp. SHU308].	25.17	580	332	21	3	538	5	526	1e-18	100
rs:XP_009698988	PREDICTED: DNA topoisomerase 3-beta-1 [Cariama cristata].	22.73	607	388	19	3	564	5	575	1e-18	100
tr:A0A016WJY4_9BILA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.77	551	346	21	46	560	28	540	1e-18	100
rs:WP_018371247	DNA topoisomerase I [Streptococcus massiliensis].	24.46	560	348	22	103	629	90	607	1e-18	100
rs:WP_017913294	DNA topoisomerase I [Xanthomonas sp. SHU166].	25.17	580	332	21	3	538	5	526	1e-18	100
tr:A0A090TAB4_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.41	598	374	18	73	633	76	632	1e-18	100
rs:WP_025306605	DNA topoisomerase I [Thermocrinis ruber].	26.71	453	281	16	83	524	57	469	1e-18	100
rs:WP_047008550	DNA topoisomerase I [Vibrio alginolyticus].	23.47	588	388	16	75	633	86	640	1e-18	100
rs:WP_024503572	DNA topoisomerase I [Mesorhizobium ciceri].	22.71	700	404	23	1	630	1	633	1e-18	100
rs:WP_012874441	DNA topoisomerase I [Thermobaculum terrenum].	22.29	682	418	23	2	631	4	625	1e-18	100
rs:WP_019614490	topoisomerase I [Psychromonas ossibalaenae].	24.87	599	368	21	74	633	88	643	1e-18	100
rs:WP_046598637	DNA topoisomerase III, partial [Staphylococcus aureus].	34.25	181	112	3	50	223	7	187	1e-18	95.9
rs:WP_039609901	DNA topoisomerase I [Pseudoalteromonas luteoviolacea].	24.42	602	369	23	72	631	84	641	1e-18	100
rs:WP_029775121	DNA topoisomerase I, partial [delta proteobacterium JGI 0000059-J07].	23.82	613	395	21	55	629	25	603	1e-18	100
rs:WP_038600921	DNA topoisomerase I [Lactococcus lactis].	24.28	556	355	20	103	629	103	621	1e-18	100
rs:WP_046594252	DNA topoisomerase III, partial [Staphylococcus aureus].	34.25	181	112	3	50	223	4	184	1e-18	95.9
rs:WP_004101389	MULTISPECIES: topoisomerase I [Klebsiella].	23.19	621	366	22	60	633	78	634	1e-18	100
rs:WP_037564696	DNA topoisomerase I [Staphylococcus agnetis].	23.55	569	374	19	90	629	67	603	1e-18	100
rs:WP_009318380	DNA topoisomerase I [Tannerella sp. 6_1_58FAA_CT1].	23.87	553	358	16	77	612	54	560	1e-18	100
rs:WP_044023756	DNA topoisomerase I, partial [Bacillus cereus].	25.16	481	311	16	105	561	82	537	1e-18	100
rs:WP_001286973	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	23.57	560	371	20	105	635	82	613	1e-18	100
rs:WP_038419681	MULTISPECIES: DNA topoisomerase I [Enterobacter].	23.92	602	365	22	76	633	82	634	1e-18	100
sp:TOP1_STAS1	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.60	557	356	18	103	629	80	602	1e-18	100
rs:WP_034738529	DNA topoisomerase I [Hyphomonas chukchiensis].	23.90	682	410	27	1	629	1	626	1e-18	100
rs:WP_028514763	DNA topoisomerase I [Ruminococcus flavefaciens].	24.38	562	353	18	90	616	66	590	1e-18	100
rs:WP_026943886	DNA topoisomerase I [Helicobacter rodentium].	22.91	646	397	20	3	614	4	582	1e-18	100
tr:F9N727_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.51	570	371	19	90	629	60	594	1e-18	100
rs:WP_041949576	hypothetical protein [Turneriella parva].	24.92	614	350	23	83	625	56	629	1e-18	100
rs:WP_025422046	DNA topoisomerase I [Sodalis praecaptivus].	23.29	584	395	15	74	633	77	631	1e-18	100
rs:WP_019792460	DNA topoisomerase I, partial [Streptococcus sobrinus].	23.54	582	367	22	83	629	44	582	1e-18	100
rs:WP_022383953	DNA topoisomerase [Bacteroides sp. CAG:462].	24.20	624	383	21	3	604	5	560	1e-18	100
tr:C2ZBM2_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.57	560	371	20	105	635	75	606	1e-18	100
rs:WP_021625049	DNA topoisomerase [Atopobium sp. oral taxon 810].	23.57	560	364	21	90	620	137	661	1e-18	100
rs:WP_044450151	DNA topoisomerase I [Mastigocladus laminosus].	22.04	676	418	23	1	629	1	614	1e-18	100
rs:WP_034649196	DNA topoisomerase I [Bacillus megaterium].	23.67	562	368	21	105	635	82	613	1e-18	100
tr:F6X812_XENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.49	618	404	20	3	585	5	582	1e-18	100
tr:V5RV70_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.77	662	403	24	1	629	1	600	1e-18	100
rs:WP_008427267	DNA topoisomerase I [Natronococcus jeotgali].	21.22	740	449	27	1	661	1	685	1e-18	100
rs:WP_038641989	DNA topoisomerase I [Pseudoalteromonas sp. OCN003].	24.79	476	290	17	187	629	197	637	1e-18	100
rs:WP_029864275	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	1e-18	100
tr:G9YWW3_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.82	561	374	17	83	614	56	586	1e-18	100
rs:XP_001740725	DNA topoisomerase 3-beta-1 [Entamoeba dispar SAW760].	23.67	452	293	13	188	615	205	628	1e-18	100
rs:WP_031927251	hypothetical protein [Staphylococcus aureus].	34.25	181	112	3	50	223	5	185	1e-18	95.9
rs:WP_025796144	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	1e-18	100
rs:WP_018868630	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	23.40	564	352	18	3	534	5	520	1e-18	100
rs:WP_018862529	DNA topoisomerase I [Thioalkalivibrio sp. ALJ3].	23.40	564	352	18	3	534	5	520	1e-18	100
rs:WP_019768655	DNA topoisomerase I [Streptococcus sobrinus].	23.54	582	367	22	83	629	87	625	1e-18	100
rs:WP_044628075	DNA topoisomerase I [Halomonas meridiana].	24.58	651	396	22	76	684	94	691	1e-18	100
rs:WP_021928053	DNA topoisomerase [Alistipes sp. CAG:831].	24.26	544	330	17	3	526	5	486	1e-18	100
rs:WP_028300153	DNA topoisomerase I [Oceanospirillum beijerinckii].	24.69	478	296	14	186	633	201	644	1e-18	100
rs:WP_046017957	DNA topoisomerase I [Marinomonas sp. S3726].	24.00	600	365	22	76	633	92	642	1e-18	100
rs:WP_044385305	DNA topoisomerase I [Marinobacter excellens].	24.08	598	379	21	72	633	86	644	1e-18	100
rs:WP_019399203	DNA topoisomerase I [Pseudoxanthomonas sp. GW2].	25.64	468	295	13	103	538	80	526	1e-18	100
rs:WP_045106988	DNA topoisomerase I [Legionella hackeliae].	24.01	629	387	26	55	630	29	619	1e-18	100
rs:WP_038471906	DNA topoisomerase I [Cedecea neteri].	24.25	602	374	23	73	633	74	634	1e-18	100
tr:I4BAN4_TURPD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.92	614	350	23	83	625	77	650	1e-18	100
rs:XP_003803330	PREDICTED: DNA topoisomerase 3-beta-1 [Otolemur garnettii].	21.92	634	399	21	3	585	5	593	1e-18	100
rs:WP_022571625	DNA topoisomerase I [Rhodobacteraceae bacterium HIMB11].	24.85	664	382	29	1	611	1	600	1e-18	100
tr:C6XEP4_METGS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.39	652	405	20	3	629	5	580	1e-18	100
gp:CP010943_1100	DNA topoisomerase I [Staphylococcus aureus]	24.47	568	370	17	90	629	67	603	1e-18	100
tr:C2MPG2_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.57	560	371	20	105	635	75	606	1e-18	100
rs:XP_006623298	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X2 [Apis dorsata].	21.09	678	448	20	3	630	5	645	1e-18	100
rs:XP_009371100	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Pyrus x bretschneideri].	22.81	548	377	13	105	631	55	577	1e-18	100
tr:A8AG75_CITK8	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.92	602	376	23	73	633	74	634	1e-18	100
rs:WP_036579214	DNA topoisomerase I [Paenibacillus darwinianus].	23.77	589	374	23	88	636	62	615	1e-18	100
rs:WP_021886309	DNA topoisomerase [Clostridium sp. CAG:590].	25.15	652	376	25	83	658	60	675	1e-18	100
rs:WP_028914417	DNA topoisomerase I [Pseudoxanthomonas sp. J31].	25.64	468	295	13	103	538	80	526	1e-18	100
rs:WP_003533084	DNA topoisomerase I [[Clostridium] leptum].	25.26	578	356	20	76	616	52	590	1e-18	100
tr:D1W2V0_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.31	622	391	21	3	602	19	576	1e-18	100
rs:WP_046306525	DNA topoisomerase I [Grimontia sp. AD028].	24.42	606	360	21	74	633	86	639	1e-18	100
rs:WP_000513589	topoisomerase I [Salmonella enterica].	24.08	598	380	20	73	633	74	634	1e-18	100
rs:WP_041104791	DNA topoisomerase I [Pseudomonas stutzeri].	22.97	592	385	17	74	633	82	634	1e-18	100
rs:WP_003496397	DNA topoisomerase I [Agrobacterium tumefaciens].	23.95	668	386	27	38	630	16	636	1e-18	100
rs:WP_021935290	DNA topoisomerase [Peptostreptococcus anaerobius CAG:621].	25.93	675	385	34	3	634	5	607	1e-18	100
tr:M0TVE7_MUSAM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.72	581	372	22	39	586	24	560	1e-18	100
rs:WP_023058511	MULTISPECIES: DNA topoisomerase I [Prevotella].	23.15	622	392	21	3	602	5	562	1e-18	100
rs:WP_043331932	DNA topoisomerase I [Cobetia marina].	23.58	598	369	18	76	633	94	643	1e-18	100
rs:WP_016765407	DNA topoisomerase I [Bacillus megaterium].	23.67	562	368	21	105	635	82	613	1e-18	100
tr:A7NJW2_ROSCS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.80	658	405	19	2	610	4	607	1e-18	100
rs:WP_034635714	DNA topoisomerase I [Bacillus manliponensis].	23.48	558	360	19	105	629	82	605	2e-18	100
rs:WP_031659876	DNA topoisomerase I [Listeria monocytogenes].	23.10	554	367	18	105	629	82	605	2e-18	100
rs:WP_025534169	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
tr:J7CFA4_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJY32177.1}; Flags: Fragment;	27.04	270	181	6	413	667	16	284	2e-18	97.4
rs:WP_014870995	topoisomerase I [Marinobacter sp. BSs20148].	24.21	599	379	22	72	633	86	646	2e-18	100
rs:WP_039997963	DNA topoisomerase I [Flavonifractor plautii].	22.82	561	374	17	83	614	61	591	2e-18	100
rs:WP_026662512	DNA topoisomerase I [Butyrivibrio proteoclasticus].	24.91	562	349	20	90	616	61	584	2e-18	100
tr:W4RHE9_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.31	195	125	2	130	317	6	200	2e-18	96.3
rs:WP_036861839	DNA topoisomerase I [Prevotella melaninogenica].	24.34	608	354	22	3	578	5	538	2e-18	100
rs:WP_045324926	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	94	648	2e-18	100
rs:WP_045018655	DNA topoisomerase I [Rhizobium nepotum].	23.95	668	386	27	38	630	16	636	2e-18	100
rs:WP_020080960	DNA topoisomerase I [Flavobacterium sp. SCGC AAA160-P02].	25.70	533	322	18	3	521	5	477	2e-18	100
rs:WP_025613452	DNA topoisomerase I [Vibrio parahaemolyticus].	24.12	597	373	19	75	633	86	640	2e-18	100
rs:WP_045586691	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_002351232	toprim domain protein, partial [Enterococcus faecium].	32.04	181	118	4	3	179	4	183	2e-18	95.1
tr:A0A0E2KMW4_VIBPH	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EQM48978.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EQM48978.1};	23.57	594	380	17	75	633	79	633	2e-18	100
rs:WP_006738721	DNA topoisomerase I [Streptococcus urinalis].	22.98	657	415	26	3	630	28	622	2e-18	100
rs:WP_035217622	DNA topoisomerase I [Agrobacterium tumefaciens].	22.98	705	399	28	1	630	1	636	2e-18	100
rs:WP_025569872	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_042614482	DNA topoisomerase I [Stenotrophomonas maltophilia].	24.27	684	413	26	3	638	5	631	2e-18	100
rs:WP_045568957	DNA topoisomerase I [Vibrio sp. S234-5].	24.03	595	376	20	75	633	85	639	2e-18	100
rs:WP_022370128	DNA topoisomerase type IA central domain protein [Eggerthella sp. CAG:368].	25.80	562	334	23	90	616	135	648	2e-18	100
rs:WP_009207200	DNA topoisomerase I [Sulfuricella denitrificans].	23.70	633	375	22	74	648	51	633	2e-18	100
rs:WP_029855921	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_025508709	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_034933050	DNA topoisomerase I [Erwinia mallotivora].	23.73	611	379	18	57	633	77	634	2e-18	100
rs:WP_044128842	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
tr:Q64CK3_9ARCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.92	662	421	27	1	629	1	619	2e-18	100
tr:F9Q4Y2_STROR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.07	540	344	18	83	597	53	551	2e-18	99.8
rs:WP_046887713	DNA topoisomerase I [Enterobacter cloacae].	23.92	602	365	22	76	633	82	634	2e-18	100
rs:WP_010649333	DNA topoisomerase I [Oceanobacillus massiliensis].	25.65	581	364	23	90	635	67	614	2e-18	100
rs:WP_031846489	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_022236962	DNA topoisomerase [Clostridium leptum CAG:27].	25.26	578	356	20	76	616	52	590	2e-18	100
rs:WP_025557280	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_040561971	DNA topoisomerase I [Prevotella buccalis].	23.31	622	391	21	3	602	5	562	2e-18	100
rs:WP_033829233	DNA topoisomerase I [Bacillus sp. KW-12].	24.28	556	362	20	103	629	80	605	2e-18	100
rs:WP_024947862	DNA topoisomerase I [Pseudomonas aeruginosa].	21.79	693	418	23	3	633	5	635	2e-18	100
rs:WP_007202531	DNA topoisomerase I [Fictibacillus macauensis].	24.65	572	363	21	100	636	77	615	2e-18	100
rs:WP_014832223	topoisomerase I [Enterobacter cloacae].	23.92	602	365	22	76	633	82	634	2e-18	100
rs:WP_043094550	DNA topoisomerase I [Xanthomonas sacchari].	25.17	580	332	21	3	538	5	526	2e-18	100
rs:WP_020214756	DNA topoisomerase I [Flavobacterium rivuli].	24.67	531	330	18	3	521	5	477	2e-18	100
rs:WP_036514469	DNA topoisomerase I [Nitrincola sp. AK23].	23.79	601	365	19	76	633	93	643	2e-18	100
rs:WP_029859090	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_003088291	DNA topoisomerase I [Streptococcus ratti].	23.53	578	374	20	83	630	78	617	2e-18	100
rs:WP_011702101	DNA topoisomerase I [Listeria welshimeri].	23.20	556	364	19	105	629	82	605	2e-18	100
rs:WP_029808434	DNA topoisomerase I [Vibrio parahaemolyticus].	22.80	649	426	24	38	652	2	609	2e-18	100
rs:WP_009137874	MULTISPECIES: DNA topoisomerase I [Odoribacter].	24.95	541	316	19	3	520	5	478	2e-18	100
rs:XP_004466517	PREDICTED: DNA topoisomerase 3-beta-1 [Dasypus novemcinctus].	22.82	631	397	22	3	585	5	593	2e-18	100
rs:WP_022202470	DNA topoisomerase [Clostridium clostridioforme CAG:132].	23.73	569	351	19	90	616	67	594	2e-18	100
rs:WP_023048968	topoisomerase I [Pseudomonas putida].	24.64	483	290	15	186	633	195	638	2e-18	100
tr:G5Q277_SALMO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.87	595	385	20	73	633	74	634	2e-18	100
rs:WP_002173098	DNA topoisomerase I [Bacillus cereus].	23.57	560	371	20	105	635	82	613	2e-18	100
rs:WP_001286951	DNA topoisomerase I [Bacillus cereus].	23.75	560	370	20	105	635	82	613	2e-18	100
rs:WP_011922475	DNA topoisomerase I [Streptococcus suis].	22.93	580	374	18	83	629	87	626	2e-18	100
rs:WP_012897826	DNA topoisomerase I [Lactococcus lactis].	24.28	556	355	20	103	629	103	621	2e-18	100
rs:WP_025573646	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_017025175	topoisomerase I [Vibrio rumoiensis].	24.95	477	295	13	187	633	196	639	2e-18	100
rs:WP_023056255	DNA topoisomerase I [Peptoniphilus sp. BV3C26].	25.40	567	343	20	88	616	62	586	2e-18	100
rs:WP_015741453	topoisomerase I [Cronobacter turicensis].	23.92	602	376	23	73	633	74	634	2e-18	100
rs:WP_000513585	topoisomerase I [Salmonella enterica].	23.87	595	385	20	73	633	74	634	2e-18	100
rs:WP_041370740	hypothetical protein, partial [Methylovorus glucosotrophus].	22.39	652	405	20	3	629	5	580	2e-18	99.8
rs:WP_025550636	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
tr:A0A0D9XFA6_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:LPERR09G11510.1};	23.87	507	327	18	105	586	78	550	2e-18	100
rs:WP_007557136	DNA topoisomerase I [Candidatus Liberibacter americanus].	23.91	690	408	30	1	630	1	633	2e-18	100
rs:WP_039893601	DNA topoisomerase, partial [Methylobacterium mesophilicum].	23.24	611	392	23	33	580	16	612	2e-18	100
rs:WP_025629059	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_044556338	DNA topoisomerase I [Shewanella piezotolerans].	23.90	611	359	23	74	633	88	643	2e-18	100
rs:WP_027408673	DNA topoisomerase I [Anoxybacillus tepidamans].	23.73	510	332	18	156	635	131	613	2e-18	100
rs:WP_000513581	DNA topoisomerase I subunit omega [Salmonella enterica].	23.87	595	385	20	73	633	74	634	2e-18	100
rs:WP_024699954	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_045716645	DNA topoisomerase I, partial [Salmonella enterica].	23.87	595	385	20	73	633	74	634	2e-18	100
rs:WP_002483473	DNA topoisomerase 1 [Staphylococcus saprophyticus].	24.60	557	356	18	103	629	80	602	2e-18	100
tr:C2WAW0_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.75	560	370	20	105	635	52	583	2e-18	100
tr:C2S7N1_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.39	560	372	19	105	635	52	583	2e-18	100
rs:WP_019789487	DNA topoisomerase I, partial [Streptococcus sobrinus].	23.84	562	350	22	103	629	2	520	2e-18	99.8
tr:M7XYJ7_9RHIZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.24	611	392	23	33	580	7	603	2e-18	100
rs:WP_006904981	DNA topoisomerase I [Thermaerobacter subterraneus].	22.44	566	376	15	83	616	60	594	2e-18	100
rs:WP_018865472	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	23.09	563	355	16	3	534	5	520	2e-18	100
rs:WP_008461318	topoisomerase I [Enterobacter sp. Ag1].	24.42	602	373	23	73	633	74	634	2e-18	100
rs:WP_025503111	DNA topoisomerase I [Vibrio parahaemolyticus].	23.77	589	385	17	75	633	86	640	2e-18	100
rs:WP_038685971	DNA topoisomerase I [Stenotrophomonas rhizophila].	23.87	687	413	25	3	638	5	632	2e-18	100
tr:V2KZL9_SALET	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.87	595	385	20	73	633	74	634	2e-18	100
rs:WP_025636650	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_005457230	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_009596063	DNA topoisomerase I [Xanthomonas translucens].	23.11	688	416	25	3	638	5	631	2e-18	100
rs:WP_022060820	DNA topoisomerase [Corallococcus sp. CAG:1435].	23.62	690	386	26	1	630	1	609	2e-18	100
rs:WP_039303632	DNA topoisomerase I [Cedecea neteri].	24.29	597	380	20	73	633	74	634	2e-18	100
rs:WP_007788928	DNA topoisomerase I [Peptostreptococcus stomatis].	24.36	583	376	19	90	642	68	615	2e-18	100
rs:WP_020021509	hypothetical protein [alpha proteobacterium SCGC AAA536-G10].	24.64	686	399	26	1	629	1	625	2e-18	100
rs:WP_037282401	DNA topoisomerase I [Saccharibacillus sacchari].	24.23	586	375	23	88	636	62	615	2e-18	100
rs:WP_028410804	MULTISPECIES: DNA topoisomerase I [Bacillus].	23.67	562	368	21	105	635	82	613	2e-18	100
rs:WP_025545701	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_014073449	DNA topoisomerase I [Lactobacillus ruminis].	23.89	586	376	19	90	642	60	608	2e-18	100
rs:WP_028536783	DNA topoisomerase I [Paludibacterium yongneupense].	23.70	671	406	27	3	630	5	612	2e-18	100
rs:WP_045782768	DNA topoisomerase I [Klebsiella michiganensis].	24.42	602	373	23	73	633	74	634	2e-18	100
sp:TOP1_SALTI	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	23.87	595	385	20	73	633	74	634	2e-18	100
rs:WP_025520612	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_025499340	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_013778279	DNA topoisomerase I [Tepidanaerobacter acetatoxydans].	22.64	645	408	18	3	616	5	589	2e-18	100
rs:WP_027635064	DNA topoisomerase I [Clostridium butyricum].	23.74	657	389	24	2	618	4	588	2e-18	100
rs:WP_009381719	DNA topoisomerase I [Staphylococcus massiliensis].	24.46	466	302	14	90	533	67	504	2e-18	100
rs:WP_013058887	MULTISPECIES: DNA topoisomerase I [Bacillus].	23.67	562	368	21	105	635	82	613	2e-18	100
rs:WP_000513591	DNA topoisomerase 1 [Salmonella enterica].	23.87	595	385	20	73	633	74	634	2e-18	100
rs:WP_021429755	DNA topoisomerase I [[Clostridium] bifermentans].	24.78	573	339	26	103	631	81	605	2e-18	100
rs:WP_017448270	topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_012570516	DNA topoisomerase I [Coxiella burnetii].	23.37	569	347	19	3	534	5	521	2e-18	100
rs:WP_012127429	topoisomerase I [Vibrio campbellii].	23.75	602	363	18	77	633	90	640	2e-18	100
rs:WP_023240746	DNA topoisomerase 1 [Salmonella enterica].	23.87	595	385	20	73	633	74	634	2e-18	100
rs:WP_038407211	DNA topoisomerase I [Listeria ivanovii].	23.10	554	367	18	105	629	82	605	2e-18	100
rs:WP_001286953	DNA topoisomerase I [Bacillus cereus].	23.57	560	371	20	105	635	82	613	2e-18	100
rs:WP_025554134	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_028798425	DNA topoisomerase I [Streptococcus sobrinus].	23.54	582	367	22	83	629	87	625	2e-18	100
rs:XP_006769027	PREDICTED: DNA topoisomerase 3-beta-1 [Myotis davidii].	22.66	631	398	21	3	585	5	593	2e-18	100
tr:S5VI98_ENTFC	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:AGS77016.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AGS77016.1};	25.93	270	184	6	413	667	22	290	2e-18	97.1
rs:WP_037383189	DNA topoisomerase I [Smithella sp. SCADC].	25.17	604	382	20	77	643	54	624	2e-18	100
rs:WP_023206147	DNA topoisomerase I subunit omega [Salmonella enterica].	23.87	595	385	20	73	633	74	634	2e-18	100
rs:WP_029559254	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_015296478	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_023253082	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	23.87	595	385	20	73	633	74	634	2e-18	99.8
rs:WP_017249339	DNA topoisomerase I [Brevibacillus brevis].	24.02	562	370	21	103	635	80	613	2e-18	100
rs:WP_030069262	DNA topoisomerase I [Halomonas alkaliantarctica].	24.87	599	370	21	72	633	87	642	2e-18	100
rs:WP_044144925	DNA topoisomerase I, partial [Salmonella enterica].	23.87	595	385	20	73	633	74	634	2e-18	100
rs:WP_023466223	Topoisomerase IA [Candidatus Liberibacter americanus].	23.91	690	408	30	1	630	1	633	2e-18	100
rs:XP_011142892	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Harpegnathos saltator].	21.80	679	442	21	3	630	5	645	2e-18	100
rs:WP_020278186	DNA topoisomerase I [Geobacillus kaustophilus].	25.20	504	318	18	157	630	132	606	2e-18	100
tr:K1TFM0_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC68533.1}; Flags: Fragment;	32.77	177	101	6	2	170	3	169	2e-18	94.4
rs:WP_036124760	DNA topoisomerase I [Lysinibacillus sphaericus].	23.74	556	366	16	103	629	80	606	2e-18	100
rs:WP_021453706	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_012073135	topoisomerase I [Actinobacillus succinogenes].	24.26	474	299	14	187	631	196	638	2e-18	100
rs:WP_026291530	DNA topoisomerase I [Marinobacterium rhizophilum].	23.17	643	409	22	76	680	93	688	2e-18	100
rs:XP_008840414	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Nannospalax galili].	23.21	629	397	23	3	585	5	593	2e-18	100
rs:WP_004582047	DNA topoisomerase I subunit omega [Marinobacter nanhaiticus].	23.48	609	380	21	60	633	89	646	2e-18	100
rs:WP_022132257	DNA topoisomerase [Clostridium sp. CAG:242].	24.46	560	359	20	88	616	120	646	2e-18	100
rs:WP_046538212	DNA topoisomerase I [Clostridiales bacterium PH28_bin88].	22.78	553	354	17	100	616	82	597	2e-18	100
rs:WP_002574864	MULTISPECIES: DNA topoisomerase I [Lachnoclostridium].	23.73	569	351	19	90	616	67	594	2e-18	100
rs:WP_001633920	DNA topoisomerase 1 [Salmonella enterica].	23.87	595	385	20	73	633	74	634	2e-18	100
rs:WP_002347146	hypothetical protein, partial [Enterococcus faecium].	25.93	270	184	6	413	667	32	300	2e-18	97.1
tr:T1KFF4_TETUR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.12	633	401	25	3	585	5	595	2e-18	100
rs:WP_045015971	DNA topoisomerase I [Agrobacterium sp. KFB 330].	23.70	671	384	28	38	630	16	636	2e-18	100
rs:WP_029805460	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:XP_011051090	PREDICTED: DNA topoisomerase 3-beta-1 [Acromyrmex echinatior].	22.01	677	443	21	3	630	5	645	2e-18	100
rs:WP_035162822	DNA topoisomerase I [Caloranaerobacter azorensis].	24.22	677	402	27	3	635	5	614	2e-18	100
rs:XP_004607504	PREDICTED: DNA topoisomerase 3-beta-1 [Sorex araneus].	22.82	631	397	22	3	585	5	593	2e-18	100
tr:D8EYS4_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.46	601	374	21	83	640	60	623	2e-18	100
rs:WP_007312723	DNA topoisomerase I, partial [Crocosphaera watsonii].	24.09	660	393	22	1	614	1	598	2e-18	99.8
rs:WP_023243911	DNA topoisomerase 1 [Salmonella enterica].	23.87	595	385	20	73	633	74	634	2e-18	100
rs:WP_035258168	DNA topoisomerase I [Actibacterium mucosum].	23.97	680	409	25	1	629	1	623	2e-18	100
rs:WP_016505322	DNA topoisomerase I [Salmonella enterica].	23.87	595	385	20	73	633	74	634	2e-18	100
rs:WP_002111378	DNA topoisomerase I [Bacillus cereus].	23.57	560	371	20	105	635	82	613	2e-18	100
rs:WP_031416423	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
tr:A0A091CCP3_9ENTE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.52	580	365	23	90	635	68	614	2e-18	99.8
rs:WP_031233433	DNA topoisomerase I [Agrobacterium tumefaciens].	22.98	705	399	29	1	630	1	636	2e-18	100
rs:WP_021210139	topoisomerase I [Pseudomonas stutzeri].	23.59	479	298	12	187	633	194	636	2e-18	100
rs:WP_000341351	DNA topoisomerase I, partial [Streptococcus agalactiae].	24.61	508	314	21	154	630	45	514	2e-18	99.8
rs:XP_005147810	PREDICTED: DNA topoisomerase 3-beta-1 [Melopsittacus undulatus].	22.57	607	389	19	3	564	5	575	2e-18	100
rs:WP_021863724	DNA topoisomerase [Clostridium sp. CAG:715].	23.66	672	408	21	3	631	12	621	2e-18	100
rs:WP_038803946	DNA topoisomerase I, partial [Salmonella enterica].	23.87	595	385	20	73	633	74	634	2e-18	100
rs:WP_034412968	DNA topoisomerase I [Candidatus Photodesmus blepharus].	24.66	596	371	21	74	633	84	637	2e-18	100
rs:WP_025627646	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	45	599	2e-18	100
rs:XP_010118399	PREDICTED: DNA topoisomerase 3-beta-1 [Chlamydotis macqueenii].	22.73	607	388	19	3	564	5	575	2e-18	100
rs:WP_023168632	DNA topoisomerase I subunit omega [Salmonella enterica].	23.87	595	385	20	73	633	74	634	2e-18	100
rs:WP_000513592	topoisomerase I [Salmonella enterica].	23.87	595	385	20	73	633	74	634	2e-18	100
rs:WP_001286954	DNA topoisomerase I [Bacillus cereus].	23.57	560	371	20	105	635	82	613	2e-18	99.8
rs:XP_005846276	hypothetical protein CHLNCDRAFT_53167 [Chlorella variabilis].	21.19	675	444	23	3	631	8	640	2e-18	100
rs:WP_017689196	DNA topoisomerase I [Paenibacillus sp. PAMC 26794].	24.73	566	364	22	103	636	80	615	2e-18	99.8
rs:WP_020976736	DNA topoisomerase I, omega protein I [Salmonella enterica].	23.87	595	385	20	73	633	74	634	2e-18	100
rs:WP_035409985	DNA topoisomerase I [Chromohalobacter israelensis].	24.26	610	384	21	61	633	76	644	2e-18	100
rs:WP_013084804	DNA topoisomerase I [Bacillus megaterium].	23.67	562	368	21	105	635	82	613	2e-18	99.8
rs:WP_008986675	topoisomerase I [Photobacterium leiognathi].	24.34	608	374	20	60	633	86	641	2e-18	100
rs:WP_038608886	DNA topoisomerase I [Pseudomonas alkylphenolia].	25.00	476	295	15	187	633	197	639	2e-18	100
rs:WP_024732755	DNA topoisomerase I [Clostridiales bacterium VE202-14].	23.01	565	355	17	90	616	67	589	2e-18	99.8
gp:CP006631_2795	DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Newport str.]	23.87	595	385	20	73	633	76	636	2e-18	100
rs:WP_003521492	DNA topoisomerase I subunit omega [Agrobacterium tumefaciens].	22.98	705	399	29	1	630	1	636	2e-18	100
rs:WP_013531916	DNA topoisomerase I [Mesorhizobium ciceri].	22.71	700	404	23	1	630	1	633	2e-18	100
rs:XP_010010011	PREDICTED: DNA topoisomerase 3-beta-1 [Nestor notabilis].	22.90	607	387	19	3	564	5	575	2e-18	100
rs:WP_002380330	DNA topoisomerase I [Enterococcus faecalis].	25.53	564	345	24	103	629	81	606	2e-18	99.8
gp:CP007804_1672	DNA topoisomerase I [Salmonella enterica subsp. enterica serovar Typhimurium]	23.87	595	385	20	73	633	76	636	2e-18	100
rs:WP_019785014	DNA topoisomerase I [Streptococcus sobrinus].	23.54	582	367	22	83	629	87	625	2e-18	99.8
rs:WP_028918474	DNA topoisomerase I [Pseudoxanthomonas sp. J35].	26.01	469	292	15	103	538	80	526	2e-18	100
tr:C2YVB5_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.57	560	371	20	105	635	75	606	2e-18	99.8
rs:WP_045127195	DNA topoisomerase I [Photobacterium angustum].	24.62	597	374	21	73	633	83	639	2e-18	100
rs:WP_043045652	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_002352040	hypothetical protein, partial [Enterococcus faecium].	25.93	270	184	6	413	667	11	279	2e-18	96.7
rs:WP_021433769	DNA topoisomerase I [[Clostridium] bifermentans].	24.78	573	339	26	103	631	81	605	2e-18	99.8
rs:WP_040995667	DNA topoisomerase I, partial [Mesorhizobium sp. SOD10].	23.22	689	414	27	1	630	1	633	2e-18	100
rs:WP_019595578	DNA topoisomerase I [Peptostreptococcus anaerobius].	25.63	675	387	33	3	634	5	607	2e-18	99.8
rs:WP_029800337	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_027025237	DNA topoisomerase I [Mesorhizobium sp. URHA0056].	22.54	701	404	24	1	630	1	633	2e-18	100
rs:WP_041534416	DNA topoisomerase I [Petrotoga mobilis].	26.08	579	338	19	77	616	48	575	2e-18	99.8
tr:K1Q3B4_CRAGI	SubName: Full=DNA topoisomerase 3-beta-1 {ECO:0000313|EMBL:EKC25894.1};	22.12	669	445	22	3	630	5	638	2e-18	100
rs:WP_006834330	DNA topoisomerase I [Erythrobacter sp. SD-21].	22.42	678	419	26	1	629	1	620	2e-18	100
rs:XP_009564658	PREDICTED: DNA topoisomerase 3-beta-1 [Cuculus canorus].	22.73	607	388	19	3	564	5	575	2e-18	100
rs:XP_005875637	PREDICTED: DNA topoisomerase 3-beta-1 [Myotis brandtii].	22.98	631	396	22	3	585	5	593	2e-18	100
rs:WP_041122387	DNA topoisomerase I [Jeotgalibacillus alimentarius].	23.49	579	379	21	90	635	67	614	2e-18	99.8
rs:WP_035115298	DNA topoisomerase I [Clostridium sp. NCR].	24.78	573	339	26	103	631	81	605	2e-18	99.8
rs:WP_044875067	DNA topoisomerase I [Pseudomonas sp. LFM046].	23.66	596	376	18	74	633	85	637	2e-18	100
rs:WP_024614709	DNA topoisomerase I [Clostridium sp. Ade.TY].	24.40	672	391	25	2	629	4	602	2e-18	99.8
rs:WP_006453157	DNA topoisomerase I [Xanthomonas gardneri].	24.61	573	344	20	3	538	5	526	2e-18	100
sp:TOP1_BACHD	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	23.13	562	375	17	103	635	80	613	2e-18	99.8
rs:WP_043220818	DNA topoisomerase I [Pseudomonas balearica].	22.80	592	386	17	74	633	82	634	2e-18	100
rs:WP_037592149	DNA topoisomerase I [Streptococcus hongkongensis].	24.23	586	358	25	83	629	83	621	2e-18	99.8
rs:WP_012658424	DNA topoisomerase I [Streptococcus uberis].	24.23	586	358	25	83	629	83	621	2e-18	99.8
rs:WP_035662616	DNA topoisomerase I [Bacillus akibai].	24.06	557	365	19	103	630	80	607	2e-18	99.8
gpu:CP007584_1792	DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Anatum str.]	23.87	595	385	20	73	633	76	636	2e-18	100
rs:WP_025791947	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	2e-18	100
rs:WP_024846942	DNA topoisomerase I [Aminobacter sp. J41].	23.59	708	409	33	1	642	1	642	2e-18	100
rs:WP_012220043	DNA topoisomerase I [Coxiella burnetii].	23.42	568	348	18	3	534	5	521	2e-18	99.8
rs:WP_014130772	DNA topoisomerase I [Pelagibacterium halotolerans].	23.41	722	432	24	1	668	1	655	2e-18	100
rs:NP_001006181	DNA topoisomerase 3-beta-1 [Gallus gallus].	22.90	607	387	19	3	564	5	575	2e-18	100
rs:WP_027222752	DNA topoisomerase I [Legionella pneumophila].	25.31	636	393	29	55	641	29	631	2e-18	99.8
rs:WP_033893356	hypothetical protein, partial [Bacteroides sartorii].	35.21	142	83	4	1	139	18	153	2e-18	94.4
rs:WP_039808869	DNA topoisomerase I [Jeotgalibacillus sp. D5].	24.40	586	365	24	90	635	67	614	2e-18	99.8
rs:WP_022020244	DNA topoisomerase [Bacteroides sp. CAG:661].	24.36	624	371	21	3	596	5	557	2e-18	99.8
rs:WP_002353633	hypothetical protein, partial [Enterococcus faecium].	25.93	270	184	6	413	667	12	280	2e-18	96.7
rs:WP_034821739	DNA topoisomerase I [[Eubacterium] nodatum].	25.64	511	312	19	157	638	135	606	3e-18	99.8
rs:WP_002160736	DNA topoisomerase I [Bacillus cereus].	23.57	560	371	20	105	635	82	613	3e-18	99.8
rs:WP_001286972	DNA topoisomerase I [Bacillus cereus].	23.57	560	371	20	105	635	82	613	3e-18	99.8
rs:WP_007256547	DNA topoisomerase I [Oceanicola granulosus].	22.03	708	446	25	1	659	1	651	3e-18	100
rs:WP_046466609	DNA topoisomerase I [Staphylococcus pasteuri].	24.28	556	360	19	103	629	80	603	3e-18	99.8
rs:WP_044050185	DNA topoisomerase I [Planktomarina temperata].	23.70	557	353	20	1	534	1	508	3e-18	100
tr:R2W309_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOI37143.1};	29.13	230	147	6	453	667	1	229	3e-18	95.9
rs:WP_010603531	DNA topoisomerase type IA central domain-containing protein, partial [Pedobacter agri].	33.52	182	101	5	1	170	1	174	3e-18	94.4
rs:WP_025612444	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	3e-18	100
rs:WP_017753743	DNA topoisomerase I [Bacillus sp. ZYK].	24.46	560	356	23	103	629	80	605	3e-18	99.8
rs:WP_018368536	DNA topoisomerase I [Streptococcus entericus].	22.98	583	369	22	83	629	71	609	3e-18	99.8
rs:XP_006099574	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Myotis lucifugus].	22.98	631	396	22	3	585	5	593	3e-18	100
rs:WP_027448276	DNA topoisomerase I [Pontibacillus marinus].	23.94	564	365	19	105	635	82	614	3e-18	99.8
rs:WP_024025561	topoisomerase I [Marinomonas profundimaris].	22.50	600	378	19	74	633	90	642	3e-18	100
rs:XP_006623297	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X1 [Apis dorsata].	21.09	678	448	20	3	630	5	645	3e-18	100
rs:WP_018250099	hypothetical protein [Orenia marismortui].	23.60	678	418	26	3	644	11	624	3e-18	99.8
rs:WP_026300384	DNA topoisomerase I [Halomonas lutea].	25.10	478	293	14	186	633	201	643	3e-18	100
rs:WP_015697113	topoisomerase I [Rahnella aquatilis].	24.04	653	380	24	76	673	82	673	3e-18	100
rs:WP_005769743	DNA topoisomerase I [Coxiella burnetii].	23.42	568	348	18	3	534	5	521	3e-18	99.8
rs:XP_002058130	GJ15664 [Drosophila virilis].	22.33	618	406	20	3	585	5	583	3e-18	99.8
rs:XP_004147675	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Cucumis sativus].	22.59	664	445	22	3	630	7	637	3e-18	100
rs:WP_035369177	DNA topoisomerase I [Acholeplasma hippikon].	24.30	609	387	22	44	629	30	587	3e-18	99.4
rs:WP_043868917	DNA topoisomerase I [Celeribacter indicus].	21.94	711	402	29	1	629	1	640	3e-18	100
tr:A0A090EG08_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.22	689	414	27	1	630	1	633	3e-18	99.8
rs:WP_017033749	topoisomerase I [Vibrio genomosp. F10].	24.90	502	311	14	163	633	173	639	3e-18	100
rs:WP_027081111	DNA topoisomerase I [Luteimonas mephitis].	24.95	473	294	16	100	536	77	524	3e-18	99.8
tr:J3C607_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952}; Flags: Precursor;	24.33	674	415	24	3	659	12	607	3e-18	99.8
rs:WP_021872352	DNA topoisomerase [Clostridium sp. CAG:1193].	23.20	651	417	18	3	629	4	595	3e-18	99.4
rs:WP_035341963	DNA topoisomerase I [Dickeya sp. DW 0440].	22.34	640	410	19	75	673	80	673	3e-18	99.8
rs:WP_013854176	DNA topoisomerase I [Lactobacillus kefiranofaciens].	24.82	568	354	22	103	635	98	627	3e-18	99.8
tr:S8D4C5_9LAMI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.31	613	365	25	64	610	65	644	3e-18	99.8
rs:WP_012961976	DNA topoisomerase I [Streptococcus gallolyticus].	22.82	561	359	20	103	630	106	625	3e-18	99.8
rs:WP_044175323	DNA topoisomerase I [Photobacterium damselae].	23.97	584	384	15	77	633	90	640	3e-18	99.8
tr:A0A0A1WJC1_BACCU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.80	383	251	11	188	560	211	566	3e-18	99.8
rs:XP_001418460	predicted protein, partial [Ostreococcus lucimarinus CCE9901].	23.14	631	388	26	84	644	123	726	3e-18	99.8
gpu:CP011232_515	DNA topoisomerase I [Kosmotoga pacifica]	24.14	671	395	24	3	630	5	604	3e-18	99.8
rs:WP_031854645	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	23.80	584	373	16	83	633	3	547	3e-18	99.8
rs:WP_005772159	DNA topoisomerase I [Coxiella burnetii].	23.42	568	348	18	3	534	5	521	3e-18	99.8
tr:A0A068Y8Q8_ECHMU	SubName: Full=DNA topoisomerase 3 beta 1 {ECO:0000313|EMBL:CDS39641.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDS39641.1};	22.64	689	426	28	3	629	29	672	3e-18	99.8
rs:WP_018375537	DNA topoisomerase I [Streptococcus orisratti].	22.55	581	376	20	83	630	82	621	3e-18	99.8
rs:WP_019029394	topoisomerase I [Colwellia piezophila].	23.38	663	408	23	65	680	75	684	3e-18	99.8
rs:XP_011176901	PREDICTED: DNA topoisomerase 3-beta [Bactrocera cucurbitae].	24.80	383	251	11	188	560	211	566	3e-18	99.8
rs:WP_017151250	DNA topoisomerase I [Bacillus sp. FJAT-13831].	23.57	560	371	20	105	635	82	613	3e-18	99.4
rs:XP_011211844	PREDICTED: DNA topoisomerase 3-beta [Bactrocera dorsalis].	24.74	380	255	9	188	560	211	566	3e-18	99.8
rs:WP_027611447	DNA topoisomerase I [Pseudomonas sp. URIL14HWK12:I6].	23.52	591	383	19	74	633	87	639	3e-18	99.8
rs:XP_010597196	PREDICTED: DNA topoisomerase 3-beta-1 [Loxodonta africana].	23.17	630	396	23	3	585	5	593	3e-18	99.8
rs:WP_012980200	DNA topoisomerase I [Methanocaldococcus sp. FS406-22].	30.68	339	197	14	3	322	4	323	3e-18	100
rs:WP_012980200	DNA topoisomerase I [Methanocaldococcus sp. FS406-22].	28.25	223	122	7	459	668	674	871	1e-06	62.8
rs:WP_025022073	DNA topoisomerase I [Lactobacillus hayakitensis].	23.89	561	354	19	103	629	97	618	3e-18	99.4
rs:WP_013366501	topoisomerase I [Enterobacter lignolyticus].	22.90	594	385	18	74	633	80	634	3e-18	99.8
rs:WP_041686590	DNA topoisomerase I [Ethanoligenens harbinense].	23.82	634	393	25	90	674	76	668	3e-18	99.8
tr:A0A0D6B246_RHOSU	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:BAQ68950.1}; EC=5.99.1.2 {ECO:0000313|EMBL:BAQ68950.1};	21.83	710	433	24	1	630	1	668	3e-18	99.8
rs:WP_027161474	DNA topoisomerase I [Mesorhizobium sp. WSM1293].	22.71	700	404	23	1	630	1	633	3e-18	99.8
rs:WP_041412994	DNA topoisomerase I [Shewanella sp. ANA-3].	24.02	483	292	16	186	631	197	641	3e-18	99.8
rs:WP_022948084	DNA topoisomerase I [Methylohalobius crimeensis].	23.75	598	370	21	81	629	58	618	3e-18	99.8
rs:WP_023015697	DNA topoisomerase I [Staphylococcus simulans].	24.30	465	303	12	90	533	67	503	3e-18	99.4
rs:WP_007970275	DNA topoisomerase I [Xanthomonas fuscans].	23.91	573	348	20	3	538	5	526	3e-18	99.8
rs:WP_022243320	GTP-sensing transcriptional pleiotropic repressor CodY [Roseburia sp. CAG:45].	23.45	563	357	17	90	616	67	591	3e-18	99.4
rs:WP_029798096	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	3e-18	99.8
rs:WP_038413679	DNA topoisomerase I [Bacillus thuringiensis].	23.93	560	369	20	105	635	82	613	3e-18	99.4
rs:WP_014092677	DNA topoisomerase I [Listeria ivanovii].	22.92	554	368	18	105	629	82	605	3e-18	99.4
rs:WP_015954503	DNA topoisomerase I [Cyanothece sp. PCC 7424].	24.44	577	355	17	85	615	67	608	3e-18	99.4
tr:E6U7W7_ETHHY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.13	634	391	25	90	674	66	658	3e-18	99.4
rs:WP_018981455	topoisomerase I [Salinimonas chungwhensis].	24.17	629	356	25	65	633	75	642	3e-18	99.8
rs:WP_010958589	DNA topoisomerase I [Coxiella burnetii].	23.42	568	348	18	3	534	5	521	3e-18	99.8
rs:WP_016415618	topoisomerase I [Halomonas anticariensis].	25.16	481	289	15	186	633	201	643	3e-18	99.8
rs:WP_019124724	DNA topoisomerase I [Peptoniphilus grossensis].	23.65	647	398	23	3	616	5	588	3e-18	99.4
rs:XP_005612443	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Equus caballus].	22.89	629	399	22	3	585	5	593	3e-18	99.8
rs:WP_005720234	DNA topoisomerase I [Lactobacillus crispatus].	24.56	570	353	21	103	635	92	621	3e-18	99.4
rs:WP_001649179	DNA topoisomerase I [Salmonella enterica].	23.87	595	385	20	73	633	74	634	3e-18	99.8
rs:WP_020255499	hypothetical protein [Parcubacteria bacterium SCGC AAA010-E09].	25.34	655	392	25	1	629	1	584	3e-18	99.4
rs:WP_023665871	DNA topoisomerase I [Rhodobacter sp. CACIA14H1].	23.03	725	418	32	1	654	1	656	3e-18	99.8
rs:WP_035745753	DNA topoisomerase I [Haematobacter missouriensis].	23.94	635	383	24	55	630	27	620	3e-18	99.8
tr:H7PSL3_STREE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.61	504	321	16	154	629	37	504	3e-18	99.0
rs:WP_046922440	DNA topoisomerase I [Lactobacillus ruminis].	24.53	587	371	22	90	642	87	635	3e-18	99.4
rs:WP_011445453	DNA topoisomerase I [Novosphingobium aromaticivorans].	21.60	676	424	22	1	629	1	617	3e-18	99.8
rs:WP_005360176	DNA topoisomerase I [Eubacterium ventriosum].	22.91	646	403	18	3	616	5	587	3e-18	99.4
rs:WP_031561748	DNA topoisomerase I [Ruminococcus flavefaciens].	25.04	563	348	20	90	616	66	590	3e-18	99.4
tr:A9BI47_PETMO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.08	579	338	19	77	616	67	594	3e-18	99.8
rs:WP_002350395	hypothetical protein, partial [Enterococcus faecium].	25.93	270	184	6	413	667	12	280	3e-18	96.3
rs:WP_033918373	DNA topoisomerase I [Listeria monocytogenes].	22.92	554	368	18	105	629	82	605	3e-18	99.4
rs:WP_028887838	DNA topoisomerase I [Tenacibaculum ovolyticum].	26.12	536	316	20	3	521	5	477	3e-18	99.8
tr:C2XXU4_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.57	560	371	20	105	635	52	583	3e-18	99.4
tr:A0A0B8Q1Z1_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAM73505.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAM73505.1};	30.05	203	136	3	381	581	1	199	3e-18	95.5
tr:A0A099VSN8_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.16	652	391	22	3	614	4	585	3e-18	99.4
rs:WP_010340683	DNA topoisomerase I [Xanthomonas sacchari].	25.00	580	333	21	3	538	5	526	3e-18	99.8
rs:WP_020696273	hypothetical protein [Reyranella massiliensis].	23.67	638	394	24	55	630	27	633	3e-18	99.8
rs:WP_024650174	DNA topoisomerase III, partial [Pseudomonas syringae].	27.22	338	203	13	1	311	1	322	3e-18	96.3
rs:WP_003412162	topoisomerase I [Pseudomonas syringae].	23.87	595	376	20	74	633	87	639	3e-18	99.8
tr:D7PJP9_9FIRM	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ADF57348.1}; Flags: Fragment;	30.49	223	127	8	2	205	18	231	3e-18	95.1
rs:WP_012951572	DNA topoisomerase I [Listeria monocytogenes].	22.92	554	368	18	105	629	82	605	3e-18	99.4
rs:WP_024720597	DNA topoisomerase I [Clostridiales bacterium VE202-01].	24.69	644	380	26	2	611	4	576	3e-18	99.4
rs:WP_022846308	DNA topoisomerase I [Desulfurobacterium sp. TC5-1].	24.85	668	397	25	2	630	7	608	3e-18	99.4
tr:G5JN01_STRCG	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.38	581	377	20	83	630	100	639	3e-18	99.4
tr:A0A0A2VZ73_BEABA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.29	597	380	20	73	633	74	634	3e-18	99.8
rs:WP_042944939	DNA topoisomerase I [Klebsiella oxytoca].	23.03	621	367	22	60	633	78	634	3e-18	99.8
rs:WP_027486209	DNA topoisomerase I [Rhizobium undicola].	22.92	698	407	29	1	630	1	635	3e-18	99.8
rs:WP_040443079	DNA topoisomerase I, partial [Ktedonobacter racemifer].	21.88	690	413	24	2	630	4	628	3e-18	99.4
rs:WP_036549903	DNA topoisomerase I [Nitrincola lacisaponensis].	24.07	619	365	25	57	633	89	644	3e-18	99.8
rs:WP_047265411	DNA topoisomerase I [Marinitoga sp. 1155].	26.01	592	368	16	55	616	32	583	3e-18	99.4
rs:WP_039006187	DNA topoisomerase I [Xanthomonas translucens].	23.11	688	416	25	3	638	5	631	3e-18	99.8
rs:WP_003727517	DNA topoisomerase I [Listeria monocytogenes].	22.92	554	368	18	105	629	82	605	3e-18	99.4
rs:XP_008695765	PREDICTED: DNA topoisomerase 3-beta-1 [Ursus maritimus].	22.66	631	398	22	3	585	5	593	3e-18	99.8
rs:WP_046324810	DNA topoisomerase I [Lactobacillus melliventris].	24.96	565	343	21	103	629	89	610	3e-18	99.4
rs:WP_016424904	DNA topoisomerase 1 [Staphylococcus sp. HGB0015].	23.51	570	373	20	90	629	67	603	3e-18	99.4
rs:WP_028086981	DNA topoisomerase I [Dorea longicatena].	23.52	557	363	18	90	616	67	590	3e-18	99.4
rs:WP_002573299	DNA topoisomerase I [[Clostridium] bolteae].	23.73	569	351	19	90	616	67	594	3e-18	99.4
rs:WP_043521232	DNA topoisomerase I [Klebsiella pneumoniae].	23.44	610	378	19	60	633	78	634	3e-18	99.8
rs:WP_023502268	Topoisomerase IA [uncultured archaeon A07HN63].	25.35	426	262	15	3	394	7	410	3e-18	99.8
rs:WP_034078458	DNA topoisomerase I [Pseudomonas aeruginosa].	22.70	599	378	19	74	633	85	637	3e-18	99.8
rs:WP_034327379	MULTISPECIES: TopA [Helicobacter].	24.59	488	317	13	77	537	46	509	3e-18	99.0
rs:WP_021475572	DNA topoisomerase I [Pseudogulbenkiania ferrooxidans].	23.46	584	378	17	84	630	61	612	3e-18	99.4
rs:WP_011247121	DNA topoisomerase I [Bacillus clausii].	24.73	562	354	20	103	630	80	606	3e-18	99.4
rs:WP_044135493	DNA topoisomerase I, partial [Bacteroides fragilis].	28.17	213	126	7	470	680	64	251	3e-18	95.9
rs:WP_031819753	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	24.85	499	315	14	163	633	62	528	3e-18	99.4
rs:WP_046332083	DNA topoisomerase I [Lactobacillus kimbladii].	24.46	560	352	20	103	629	89	610	3e-18	99.4
rs:WP_008876148	DNA topoisomerase 1 [Mesorhizobium metallidurans].	22.57	700	405	26	1	630	1	633	3e-18	99.8
rs:WP_003732799	DNA topoisomerase I [Listeria monocytogenes].	22.92	554	368	18	105	629	82	605	3e-18	99.4
rs:XP_010673316	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Beta vulgaris subsp. vulgaris].	22.56	616	396	21	54	631	6	578	3e-18	99.4
rs:WP_014229012	MULTISPECIES: topoisomerase I [Klebsiella].	23.03	621	367	22	60	633	78	634	3e-18	99.8
rs:WP_015840249	topoisomerase I [Pectobacterium carotovorum].	24.79	601	365	23	75	633	80	635	3e-18	99.8
rs:WP_026749247	DNA topoisomerase I [Leptotrichia trevisanii].	24.39	619	371	22	2	589	4	556	3e-18	99.4
rs:WP_016297112	DNA topoisomerase I [Lachnospiraceae bacterium M18-1].	23.82	613	364	22	90	630	67	648	3e-18	99.4
rs:WP_005506017	topoisomerase I [Grimontia hollisae].	24.63	605	360	22	74	633	86	639	3e-18	99.8
rs:WP_004112425	topoisomerase I [Klebsiella oxytoca].	23.19	621	366	22	60	633	78	634	3e-18	99.8
rs:WP_018699100	hypothetical protein [Amorphus coralli].	22.55	683	425	24	1	630	1	632	3e-18	99.8
rs:WP_033975944	DNA topoisomerase 1 [Pseudomonas aeruginosa].	22.56	594	385	18	74	633	85	637	3e-18	99.8
rs:WP_027976116	DNA topoisomerase I [Streptococcus devriesei].	23.37	582	370	21	83	630	78	617	3e-18	99.4
rs:WP_003738814	DNA topoisomerase I [Listeria monocytogenes].	22.92	554	368	18	105	629	82	605	3e-18	99.4
rs:WP_024524613	DNA topoisomerase I [Edwardsiella hoshinae].	22.82	517	336	12	187	673	190	673	3e-18	99.8
rs:WP_021167566	DNA topoisomerase 1 [Sporomusa ovata].	24.47	662	384	27	3	616	5	598	3e-18	99.4
rs:WP_042124336	DNA topoisomerase I [Pseudomonas japonica].	23.81	483	294	15	186	633	195	638	3e-18	99.8
rs:WP_009924617	DNA topoisomerase I [Listeria monocytogenes].	22.92	554	368	18	105	629	82	605	3e-18	99.4
rs:XP_002732450	PREDICTED: DNA topoisomerase 3-alpha-like [Saccoglossus kowalevskii].	22.90	620	371	25	77	634	111	685	3e-18	99.8
rs:WP_029039839	DNA topoisomerase I [Cucumibacter marinus].	22.46	690	414	22	1	630	1	629	3e-18	99.8
rs:WP_022785614	DNA topoisomerase I [Clostridiales bacterium NK3B98].	22.89	568	370	14	83	616	61	594	3e-18	99.4
rs:XP_009132831	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Brassica rapa].	22.12	556	370	16	66	586	34	561	4e-18	99.4
rs:WP_013638549	DNA topoisomerase I [Desulfurobacterium thermolithotrophum].	23.76	665	405	24	2	629	5	604	4e-18	99.4
rs:WP_043953492	DNA topoisomerase I [Enterobacter sp. YD4].	23.68	604	375	22	73	633	74	634	4e-18	99.4
rs:WP_007087757	DNA topoisomerase I [Bacillus bataviensis].	23.90	569	363	21	103	635	81	615	4e-18	99.4
rs:WP_041888640	DNA topoisomerase I, partial [Candidatus Aerophobus profundus].	25.51	588	362	20	77	629	54	600	4e-18	99.4
rs:WP_023404807	DNA topoisomerase I [Vibrio halioticoli].	24.66	515	296	19	163	633	173	639	4e-18	99.4
rs:WP_025260740	DNA topoisomerase I [Pseudomonas cichorii].	23.99	592	379	20	74	633	87	639	4e-18	99.4
rs:WP_022279654	DNA topoisomerase [Dorea formicigenerans CAG:28].	23.27	520	324	18	187	671	17	496	4e-18	98.6
rs:WP_007014845	DNA topoisomerase I [Novosphingobium pentaromativorans].	22.60	677	414	23	1	629	1	615	4e-18	99.4
rs:XP_012170324	PREDICTED: DNA topoisomerase 3-beta-1 [Bombus terrestris].	21.12	677	449	20	3	630	5	645	4e-18	99.4
rs:WP_022560127	MULTISPECIES: DNA topoisomerase 1 [Xanthomonas].	23.91	573	348	20	3	538	5	526	4e-18	99.4
rs:WP_031806813	DNA topoisomerase III, partial [Staphylococcus aureus].	30.20	245	143	5	381	615	1	227	4e-18	96.3
rs:WP_043411915	DNA topoisomerase III, partial [Streptomyces pluripotens].	30.05	193	129	3	345	537	32	218	4e-18	95.1
rs:WP_003428420	DNA topoisomerase [Clostridium butyricum].	23.74	657	389	24	2	618	4	588	4e-18	99.4
rs:WP_022441506	DNA topoisomerase [Clostridium sp. CAG:768].	24.33	674	401	24	3	631	14	623	4e-18	99.4
rs:WP_002564492	DNA topoisomerase I [[Clostridium] bolteae].	23.73	569	351	19	90	616	67	594	4e-18	99.0
rs:WP_043640256	DNA topoisomerase I [Desulfovibrio sp. TomC].	24.05	603	363	26	79	640	52	600	4e-18	99.0
rs:WP_022972837	DNA topoisomerase I, partial [Xanthomonas sp. M97].	24.01	579	340	23	3	538	5	526	4e-18	99.0
rs:WP_007961815	topoisomerase I [Pseudomonas sp. GM30].	23.52	591	383	19	74	633	87	639	4e-18	99.4
tr:A0A0A6PH49_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.26	476	280	14	103	538	80	524	4e-18	99.4
rs:WP_006780289	DNA topoisomerase I [[Clostridium] hathewayi].	24.38	566	348	21	90	616	67	591	4e-18	99.0
rs:WP_002579620	DNA topoisomerase I [Clostridium butyricum].	23.74	657	389	24	2	618	4	588	4e-18	99.0
tr:U6D9Q2_NEOVI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.66	631	398	22	3	585	5	593	4e-18	99.4
rs:WP_027859126	DNA topoisomerase I [Marinobacterium jannaschii].	23.95	593	360	23	83	633	100	643	4e-18	99.4
rs:WP_008890785	DNA topoisomerase I [Thalassospira profundimaris].	23.09	706	411	26	1	639	1	641	4e-18	99.4
rs:WP_009010972	DNA topoisomerase I [Prevotella sp. C561].	24.01	608	360	21	3	580	5	540	4e-18	99.4
rs:WP_003406572	DNA topoisomerase I [Clostridium butyricum].	23.90	657	388	24	2	618	4	588	4e-18	99.0
rs:WP_038883495	DNA topoisomerase I [Cronobacter dublinensis].	24.09	606	370	22	73	633	74	634	4e-18	99.4
rs:XP_008840420	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Nannospalax galili].	22.97	627	396	23	3	585	5	588	4e-18	99.4
rs:WP_002480688	DNA topoisomerase 1 [Staphylococcus simulans].	24.30	465	303	12	90	533	67	503	4e-18	99.0
rs:WP_041517486	DNA topoisomerase I [Flavobacterium hibernum].	25.33	533	324	19	3	521	5	477	4e-18	99.4
tr:A0KVZ3_SHESA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.02	483	292	16	186	631	213	657	4e-18	99.4
rs:WP_012824940	DNA topoisomerase I [Halothiobacillus neapolitanus].	23.94	493	310	15	81	534	58	524	4e-18	99.4
rs:WP_039929908	DNA topoisomerase I, partial [Lactobacillus oris].	24.31	580	354	23	90	629	85	619	4e-18	99.0
rs:WP_037209660	DNA topoisomerase I [Rhodovulum sp. NI22].	23.09	628	381	21	1	589	1	565	4e-18	99.4
rs:WP_027596626	DNA topoisomerase I [Pseudomonas sp. LAIL14HWK12:I7].	24.58	476	299	14	186	633	195	638	4e-18	99.4
rs:WP_022064027	DNA topoisomerase [Alistipes sp. CAG:157].	24.64	625	369	24	3	604	18	563	4e-18	99.4
rs:WP_023913525	DNA topoisomerase I [Rhodobacter capsulatus].	23.04	677	427	21	1	638	1	622	4e-18	99.4
rs:WP_011411228	topoisomerase I [Sodalis glossinidius].	22.60	584	399	13	74	633	77	631	4e-18	99.4
rs:WP_037388606	DNA topoisomerase III, partial [Serratia symbiotica].	29.74	232	141	7	1	221	1	221	4e-18	94.7
rs:WP_015868991	DNA topoisomerase I [Kosmotoga olearia].	22.95	645	386	23	2	607	4	576	4e-18	99.4
rs:WP_007964211	DNA topoisomerase I [Xanthomonas fuscans].	23.91	573	348	20	3	538	5	526	4e-18	99.4
rs:WP_044976306	DNA topoisomerase I [Ruminococcus sp. HUN007].	25.04	563	350	19	90	616	66	592	4e-18	99.0
rs:WP_039836543	DNA topoisomerase I [Paenibacillus sonchi].	23.71	582	383	21	88	636	62	615	4e-18	99.0
rs:WP_031437885	DNA topoisomerase I [Methylobacter tundripaludum].	24.39	574	335	22	3	534	5	521	4e-18	99.4
rs:WP_038871634	DNA topoisomerase I [Cronobacter dublinensis].	24.09	606	370	22	73	633	74	634	4e-18	99.4
rs:WP_037039426	DNA topoisomerase I [Pseudomonas sp. BAY1663].	24.06	478	297	13	187	633	193	635	4e-18	99.4
rs:WP_009686278	MULTISPECIES: topoisomerase I [Pseudomonas].	24.07	482	294	14	186	633	195	638	4e-18	99.4
rs:WP_015269531	MULTISPECIES: DNA topoisomerase I subunit omega [Pseudomonas].	24.58	476	299	14	186	633	195	638	4e-18	99.4
rs:WP_019320014	DNA topoisomerase I [Streptococcus mutans].	23.50	583	368	23	83	630	78	617	4e-18	99.0
rs:XP_004680993	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Condylura cristata].	22.59	633	396	22	3	585	5	593	4e-18	99.4
rs:WP_040929149	DNA topoisomerase I [Nosocomiicoccus sp. NP2].	23.59	568	363	22	103	635	80	611	4e-18	99.0
rs:WP_042001259	DNA topoisomerase I [Capnocytophaga canimorsus].	26.33	528	325	17	3	521	5	477	4e-18	99.4
rs:WP_023575396	DNA topoisomerase I [Flavobacterium saliperosum].	25.38	532	325	20	3	521	5	477	4e-18	99.4
rs:XP_011555583	PREDICTED: DNA topoisomerase 3-beta-1 [Plutella xylostella].	22.36	501	325	15	188	655	211	680	4e-18	99.4
rs:WP_035307621	DNA topoisomerase I [Clostridium sp. HMP27].	25.60	543	341	17	103	616	80	588	4e-18	99.0
rs:XP_004742574	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Mustela putorius furo].	22.66	631	398	22	3	585	5	593	4e-18	99.4
rs:WP_032749439	DNA topoisomerase I [Klebsiella oxytoca].	23.23	607	383	19	60	633	78	634	4e-18	99.4
rs:WP_032108967	DNA topoisomerase I [Haemophilus sp. FF7].	26.18	489	275	19	187	633	196	640	4e-18	99.4
rs:WP_031640548	DNA topoisomerase I [Pseudomonas aeruginosa].	22.54	599	379	19	74	633	85	637	4e-18	99.4
rs:WP_022090080	DNA topoisomerase [Clostridium sp. CAG:492].	23.24	555	371	16	89	616	63	589	4e-18	99.0
rs:XP_012579341	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Condylura cristata].	22.70	630	399	22	3	585	5	593	4e-18	99.0
tr:F7LSI9_9BACE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGN05988.1};	32.11	218	91	7	467	629	67	282	4e-18	95.9
rs:WP_028790321	DNA topoisomerase I [Tetragenococcus muriaticus].	25.30	581	365	22	90	635	68	614	4e-18	99.0
tr:F8XZ68_STRAG	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EGS28193.1};	32.34	235	149	5	350	580	23	251	4e-18	95.5
rs:WP_023582278	DNA topoisomerase I [Proteus hauseri].	23.12	545	300	20	187	673	190	673	4e-18	99.4
tr:G9KUN5_MUSPF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.66	631	398	22	3	585	5	593	4e-18	99.4
rs:WP_012498988	DNA topoisomerase I [Chloroherpeton thalassium].	25.45	609	357	24	76	629	67	633	4e-18	99.4
rs:WP_046902757	DNA topoisomerase I [Altererythrobacter atlanticus].	23.44	691	417	26	1	640	1	630	4e-18	99.4
rs:WP_047060003	DNA topoisomerase I [Edwardsiella tarda].	23.81	525	321	16	187	673	190	673	4e-18	99.4
rs:WP_022408208	DNA topoisomerase [Clostridium sp. CAG:354].	25.49	510	308	18	90	564	67	539	4e-18	99.0
rs:WP_014149842	DNA topoisomerase I [Methylomicrobium alcaliphilum].	22.67	719	446	26	3	673	5	661	4e-18	99.0
rs:WP_029823273	DNA topoisomerase I [Vibrio parahaemolyticus].	23.57	594	380	17	75	633	86	640	4e-18	99.4
rs:WP_024325912	DNA topoisomerase I [Thioalkalivibrio sp. AKL19].	23.55	569	345	20	3	534	5	520	4e-18	99.4
rs:WP_028776179	DNA topoisomerase I [Shimazuella kribbensis].	24.02	562	365	19	100	630	77	607	4e-18	99.0
rs:WP_039252884	DNA topoisomerase I [Clostridium novyi].	23.55	705	400	24	2	630	4	645	4e-18	99.0
tr:A0A023F3Y2_TRIIF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.65	605	388	20	3	560	5	570	4e-18	99.4
rs:WP_040168960	DNA topoisomerase I [Klebsiella pneumoniae].	22.77	606	387	17	60	633	78	634	4e-18	99.4
rs:WP_005285326	topoisomerase I [Edwardsiella tarda].	23.81	525	321	16	187	673	190	673	4e-18	99.4
rs:WP_012050010	DNA topoisomerase I [Sphingomonas wittichii].	22.79	724	457	28	1	675	1	671	4e-18	99.4
tr:E3C6K9_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.31	580	354	23	90	629	67	601	4e-18	99.0
rs:WP_014852237	topoisomerase I [Pseudomonas stutzeri].	23.85	478	298	14	187	633	194	636	4e-18	99.4
rs:XP_009090585	PREDICTED: DNA topoisomerase 3-beta-1 [Serinus canaria].	22.57	607	389	19	3	564	5	575	4e-18	99.4
rs:WP_039294073	DNA topoisomerase I [Cedecea neteri].	23.83	596	384	18	73	633	74	634	4e-18	99.4
rs:WP_040804917	DNA topoisomerase I [Streptococcus criceti].	22.38	581	377	20	83	630	87	626	4e-18	99.0
rs:WP_003512719	MULTISPECIES: DNA topoisomerase I [Agrobacterium].	23.80	668	387	27	38	630	16	636	4e-18	99.4
rs:WP_006649229	DNA topoisomerase I [Haloterrigena thermotolerans].	21.24	711	437	23	1	642	1	657	4e-18	99.4
rs:WP_014643263	DNA topoisomerase I [Halobacillus halophilus].	25.80	566	351	22	105	635	82	613	4e-18	99.0
rs:WP_002765685	DNA topoisomerase I [Microcystis aeruginosa].	25.37	611	350	22	3	560	4	561	4e-18	99.4
rs:WP_021630176	DNA topoisomerase I [Clostridium sp. ATCC BAA-442].	22.82	561	374	17	83	614	61	591	4e-18	99.0
rs:WP_022260022	DNA topoisomerase [Eubacterium sp. CAG:251].	24.42	692	392	30	2	637	3	619	4e-18	99.0
rs:WP_041694374	DNA topoisomerase I [Agrobacterium sp. H13-3].	23.80	668	387	27	38	630	16	636	4e-18	99.4
rs:WP_020195007	topoisomerase I [Vibrio owensii].	23.63	601	365	18	77	633	90	640	4e-18	99.4
rs:WP_008852824	DNA topoisomerase I [Gluconobacter morbifer].	22.35	689	413	28	3	629	4	632	4e-18	99.4
rs:WP_019096205	topoisomerase I [Pseudomonas putida].	24.95	477	296	15	186	633	195	638	4e-18	99.4
rs:WP_014246223	DNA topoisomerase I [Blattabacterium punctulatus].	26.21	538	310	21	3	520	5	475	4e-18	99.0
rs:WP_039447261	DNA topoisomerase I [Pedobacter glucosidilyticus].	23.83	596	367	19	3	578	5	533	4e-18	99.4
rs:WP_004086454	DNA topoisomerase I [Xylella fastidiosa].	24.26	573	346	20	3	538	5	526	4e-18	99.0
tr:A0A0D7M0I9_CITFR	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJC12167.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KJC12167.1}; Flags: Fragment;	23.48	592	391	19	73	633	74	634	4e-18	99.0
rs:WP_017222302	topoisomerase I [Moritella dasanensis].	24.41	590	376	21	77	633	86	638	4e-18	99.4
tr:B1NNY5_STREQ	SubName: Full=Truncated topoisomerase {ECO:0000313|EMBL:ACA42500.1}; Flags: Fragment;	38.96	154	84	4	73	218	1	152	4e-18	92.8
rs:WP_037406881	DNA topoisomerase I [Snodgrassella alvi].	23.00	674	409	28	3	630	5	614	4e-18	99.0
rs:WP_042527530	DNA topoisomerase I [Coxiella burnetii].	23.42	568	348	18	3	534	5	521	4e-18	99.0
rs:WP_012075146	topoisomerase I [Pseudomonas aeruginosa].	22.70	599	378	19	74	633	85	637	4e-18	99.4
rs:WP_002678704	DNA topoisomerase I [Treponema denticola].	24.91	546	334	22	163	675	157	659	4e-18	99.0
rs:WP_003140856	DNA topoisomerase I [Aerococcus viridans].	24.12	568	368	22	90	629	68	600	4e-18	99.0
rs:WP_026696251	DNA topoisomerase I [Bacillus chagannorensis].	24.06	561	352	19	105	629	82	604	4e-18	99.0
rs:WP_022103541	DNA topoisomerase [Bacteroides stercoris CAG:120].	37.89	161	87	4	467	626	20	168	5e-18	94.7
rs:WP_014838214	topoisomerase I [Klebsiella oxytoca].	23.03	621	367	22	60	633	78	634	5e-18	99.4
rs:WP_047267500	DNA topoisomerase I [Marinitoga sp. 1197].	24.84	644	386	18	3	616	8	583	5e-18	99.0
rs:WP_004254195	topoisomerase I [Providencia rettgeri].	22.80	601	377	16	74	633	83	637	5e-18	99.4
rs:WP_039841572	DNA topoisomerase I [Vibrio owensii].	23.63	601	365	18	77	633	90	640	5e-18	99.4
rs:WP_021713044	DNA topoisomerase I [Vibrio ezurae].	25.39	516	291	19	163	633	173	639	5e-18	99.4
rs:WP_035631569	DNA topoisomerase I [Flavobacterium sp. CF136].	24.18	674	416	23	3	659	5	600	5e-18	99.0
rs:WP_037490985	DNA topoisomerase I [Snodgrassella alvi].	23.00	674	409	28	3	630	5	614	5e-18	99.0
rs:WP_024992857	hypothetical protein, partial [Prevotella amnii].	30.97	226	144	7	455	677	44	260	5e-18	95.1
rs:WP_038205444	DNA topoisomerase I [Vibrio tubiashii].	24.39	615	369	19	57	633	83	639	5e-18	99.4
tr:E1F9F6_GIAIA	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFO60919.1};	25.04	643	406	26	1	589	1	621	5e-18	99.4
rs:WP_034913033	DNA topoisomerase I [Gilliamella apicola].	23.25	615	383	19	63	633	68	637	5e-18	99.0
rs:WP_046615846	DNA topoisomerase I [Pseudomonas putida].	24.58	476	299	14	186	633	195	638	5e-18	99.0
rs:WP_023398362	DNA topoisomerase I [Pseudoalteromonas luteoviolacea].	24.01	604	369	23	72	631	84	641	5e-18	99.0
rs:WP_004203874	MULTISPECIES: DNA topoisomerase I subunit omega [Klebsiella].	23.44	610	378	19	60	633	78	634	5e-18	99.0
rs:WP_028129147	DNA topoisomerase I [Selenomonas sp. AE3005].	24.91	554	358	20	90	616	97	619	5e-18	99.0
tr:M7YPL3_TRIUA	SubName: Full=DNA topoisomerase 3-beta-1 {ECO:0000313|EMBL:EMS49347.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:TRIUR3_18494-P1};	21.58	658	401	23	3	586	6	622	5e-18	99.0
rs:WP_009157827	DNA topoisomerase I [Thalassobium sp. R2A62].	22.93	615	388	19	1	585	1	559	5e-18	99.0
rs:WP_013833968	DNA topoisomerase I [Novosphingobium sp. PP1Y].	22.45	677	415	23	1	629	1	615	5e-18	99.0
tr:F0L2J3_AGRSH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.80	668	387	27	38	630	27	647	5e-18	99.0
rs:WP_029994545	DNA topoisomerase I [Sphingomonas sp. YL-JM2C].	22.79	724	457	28	1	675	1	671	5e-18	99.0
rs:WP_019340657	topoisomerase I [Pseudomonas stutzeri].	23.43	478	300	11	187	633	194	636	5e-18	99.0
rs:WP_003020611	MULTISPECIES: topoisomerase I [Citrobacter].	23.48	592	391	19	73	633	74	634	5e-18	99.0
tr:Q895L4_CLOTE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.42	564	334	21	90	616	69	588	5e-18	98.6
rs:WP_023905388	DNA topoisomerase I [Xanthomonas hortorum].	24.61	573	344	20	3	538	5	526	5e-18	99.0
rs:WP_005817708	topoisomerase I [Actinobacillus minor].	23.17	600	371	20	74	631	87	638	5e-18	99.0
rs:WP_003248770	DNA topoisomerase I [Pseudomonas putida].	24.58	476	299	14	186	633	195	638	5e-18	99.0
rs:WP_016408454	DNA topoisomerase [Firmicutes bacterium CAG:102].	23.17	643	404	24	3	616	32	613	5e-18	99.0
rs:WP_023289334	MULTISPECIES: DNA topoisomerase 1 [Klebsiella].	23.44	610	378	19	60	633	78	634	5e-18	99.0
rs:WP_032981332	DNA topoisomerase I [Cronobacter malonaticus].	23.79	597	383	20	73	633	74	634	5e-18	99.0
rs:WP_028722826	DNA topoisomerase I [Pantoea ananatis].	23.45	597	378	21	75	633	79	634	5e-18	99.0
rs:WP_038896310	DNA topoisomerase I [Vibrio owensii].	23.63	601	365	18	77	633	90	640	5e-18	99.0
rs:WP_014591780	topoisomerase I [Pseudomonas putida].	24.58	476	299	14	186	633	195	638	5e-18	99.0
rs:WP_016404385	DNA topoisomerase [Clostridium sp. CAG:1013].	23.17	643	411	23	2	616	3	590	5e-18	98.6
rs:WP_004070358	DNA topoisomerase I [Clostridium sp. ASF502].	23.04	638	394	20	90	658	67	676	5e-18	98.6
rs:WP_027229115	DNA topoisomerase I [Legionella pneumophila].	25.67	639	387	30	55	641	29	631	5e-18	99.0
tr:W7YM17_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.46	699	408	27	3	642	12	649	5e-18	98.6
rs:XP_011216356	PREDICTED: DNA topoisomerase 3-beta-1 [Ailuropoda melanoleuca].	22.50	631	399	22	3	585	5	593	5e-18	99.0
rs:WP_024359426	MULTISPECIES: DNA topoisomerase I [Klebsiella].	23.16	613	367	22	73	633	74	634	5e-18	99.0
rs:WP_018014634	topoisomerase I [Teredinibacter turnerae].	23.09	602	385	20	65	629	80	640	5e-18	99.0
tr:R7VCK8_CAPTE	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	21.28	672	451	22	3	631	5	641	5e-18	99.0
rs:WP_034290689	DNA topoisomerase I [Helicobacter sp. MIT 11-5569].	24.39	656	378	26	3	614	4	585	5e-18	99.0
gpu:CP009515_2186	DNA topoisomerase I [Methanosarcina lacustris Z-7289]	24.02	458	303	16	188	629	196	624	5e-18	99.0
rs:WP_021454958	topoisomerase I [Vibrio coralliilyticus].	23.95	593	379	16	75	633	85	639	5e-18	99.0
rs:WP_035124882	DNA topoisomerase I [Clostridium tetani].	26.42	564	334	21	90	616	67	586	5e-18	98.6
tr:A0A034TW46_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.04	612	380	19	67	633	76	641	5e-18	99.0
rs:WP_038066759	DNA topoisomerase I [Thermus filiformis].	24.26	573	320	21	100	616	90	604	5e-18	99.0
rs:XP_004895319	PREDICTED: DNA topoisomerase 3-beta-1 [Heterocephalus glaber].	23.37	629	396	23	3	585	5	593	5e-18	99.0
rs:WP_036202949	DNA topoisomerase I [Lysinibacillus sinduriensis].	24.24	557	360	18	105	630	82	607	5e-18	98.6
tr:A0A061Q1G5_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.63	601	365	18	77	633	90	640	5e-18	99.0
rs:WP_005441649	topoisomerase I [Vibrio harveyi].	23.63	601	365	18	77	633	90	640	5e-18	99.0
rs:WP_027641384	DNA topoisomerase I [[Clostridium] clostridioforme].	23.46	567	355	19	90	616	67	594	5e-18	98.6
tr:S4PFB5_9NEOP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.03	469	302	15	188	630	211	646	5e-18	99.0
rs:XP_008061294	PREDICTED: DNA topoisomerase 3-beta-1 [Tarsius syrichta].	22.77	628	401	21	3	585	5	593	5e-18	99.0
rs:WP_010713378	DNA topoisomerase 1 [Enterococcus faecalis].	25.35	564	346	24	103	629	81	606	5e-18	98.6
rs:WP_025593271	DNA topoisomerase I [Agrobacterium tumefaciens].	23.80	668	387	27	38	630	16	636	5e-18	99.0
tr:T1JEW7_STRMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.64	605	389	22	3	564	5	573	5e-18	99.0
tr:A0A068XMR0_HYMMI	SubName: Full=DNA topoisomerase 3 beta 1 {ECO:0000313|EMBL:CDS33655.1};	21.93	684	443	22	4	629	1	651	5e-18	99.0
rs:WP_009707099	topoisomerase I [Vibrio sp. HENC-03].	23.63	601	365	18	77	633	90	640	5e-18	99.0
rs:WP_022027298	DNA topoisomerase [Dialister invisus CAG:218].	23.99	646	399	20	3	616	34	619	5e-18	99.0
rs:WP_032095784	MULTISPECIES: DNA topoisomerase I [Alteromonas].	24.07	669	399	27	65	680	75	687	5e-18	99.0
rs:WP_038154321	DNA topoisomerase I [Trabulsiella guamensis].	23.41	598	377	18	74	633	80	634	5e-18	99.0
rs:WP_002382349	DNA topoisomerase I, partial [Enterococcus faecalis].	25.35	564	346	24	103	629	81	606	5e-18	98.6
rs:XP_011501910	PREDICTED: DNA topoisomerase 3-beta-1 [Ceratosolen solmsi marchali].	23.54	463	306	12	188	630	210	644	5e-18	99.0
rs:WP_034455431	DNA topoisomerase I [Buttiauxella agrestis].	24.34	604	371	24	73	633	74	634	5e-18	99.0
rs:WP_020183595	DNA topoisomerase I [Methylotenera sp. 1P/1].	24.20	657	389	25	2	614	3	594	5e-18	99.0
rs:WP_022364712	DNA topoisomerase [Clostridium sp. CAG:505].	22.84	613	367	22	90	630	85	663	5e-18	98.6
rs:XP_005233334	PREDICTED: DNA topoisomerase 3-beta-1 [Falco peregrinus].	22.41	607	390	19	3	564	5	575	5e-18	99.0
rs:WP_046093242	DNA topoisomerase I [Salmonella enterica].	23.70	595	386	20	73	633	74	634	5e-18	99.0
rs:WP_015750544	DNA topoisomerase I [Desulfohalobium retbaense].	25.39	583	342	23	76	616	53	584	6e-18	98.6
rs:WP_031834509	DNA topoisomerase III, partial [Staphylococcus aureus].	34.90	192	108	6	3	183	4	189	6e-18	93.6
rs:WP_033657820	hypothetical protein [Enterococcus faecium].	31.49	181	119	4	3	179	4	183	6e-18	94.0
rs:WP_020059168	DNA topoisomerase I [Bacillus sp. 123MFChir2].	24.44	585	381	23	103	655	80	635	6e-18	98.6
rs:WP_035109892	DNA topoisomerase I [Clostridium tetani].	26.42	564	334	21	90	616	67	586	6e-18	98.6
rs:WP_013661399	topoisomerase I [Marinomonas mediterranea].	23.97	605	359	22	76	633	92	642	6e-18	99.0
rs:WP_032894880	DNA topoisomerase I [Fusobacterium hwasookii].	24.54	603	374	19	2	580	9	554	6e-18	98.6
rs:WP_006586737	DNA topoisomerase I [Lactobacillus jensenii].	22.46	561	362	18	103	629	83	604	6e-18	98.6
tr:G5M307_SALET	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	24.31	473	304	15	187	633	2	446	6e-18	98.6
rs:WP_004121251	topoisomerase I [Klebsiella oxytoca].	23.65	613	364	23	73	633	74	634	6e-18	99.0
rs:WP_000513586	DNA topoisomerase I subunit omega [Salmonella enterica].	23.70	595	386	20	73	633	74	634	6e-18	99.0
tr:A0A0D6DXL3_9LACT	SubName: Full=DNA topoisomerase 1 TopA {ECO:0000313|EMBL:CEN28525.1};	24.09	577	370	24	83	629	132	670	6e-18	98.6
rs:WP_010642515	DNA topoisomerase I [Acidithiobacillus thiooxidans].	23.19	483	305	14	76	525	53	502	6e-18	98.6
tr:A0A0A8RCV9_PSEAI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.54	599	379	19	74	633	85	637	6e-18	99.0
rs:WP_046445616	DNA topoisomerase I [Alistipes sp. N15.MGS-157].	24.64	625	369	24	3	604	18	563	6e-18	98.6
rs:WP_002407054	DNA topoisomerase I [Enterococcus faecalis].	25.35	564	346	24	103	629	81	606	6e-18	98.6
rs:WP_002841675	DNA topoisomerase I [Finegoldia magna].	23.96	651	389	26	2	616	5	585	6e-18	98.6
rs:WP_029095051	DNA topoisomerase I [Budvicia aquatica].	24.17	600	366	19	76	633	84	636	6e-18	99.0
rs:WP_003715207	DNA topoisomerase I [Lactobacillus oris].	24.27	581	353	24	90	629	92	626	6e-18	98.6
rs:WP_039123365	DNA topoisomerase I [Lactobacillus ruminis].	24.19	587	373	22	90	642	60	608	6e-18	98.6
rs:WP_025630849	DNA topoisomerase I [Vibrio parahaemolyticus].	23.30	588	389	16	75	633	86	640	6e-18	99.0
rs:WP_031630901	DNA topoisomerase 1 [Pseudomonas aeruginosa].	22.56	594	385	18	74	633	85	637	6e-18	99.0
rs:WP_022448738	DNA topoisomerase [Roseburia sp. CAG:303].	23.29	644	405	22	3	616	5	589	6e-18	98.6
rs:WP_032077656	DNA topoisomerase I [Clostridium drakei].	24.23	648	395	23	2	616	4	588	6e-18	98.6
rs:WP_033609624	topoisomerase I, partial [Lactobacillus plantarum].	28.37	215	147	4	351	560	1	213	6e-18	94.0
tr:A0A0E0B4W4_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OGLUM09G15970.1};	23.53	408	270	12	191	586	1345	1722	6e-18	99.4
rs:WP_027473323	DNA topoisomerase I [Saccharicrinis fermentans].	24.61	699	407	27	3	642	12	649	6e-18	98.6
rs:WP_029236761	DNA topoisomerase I [Streptococcus sobrinus].	23.10	580	372	20	83	629	87	625	6e-18	98.6
tr:D4M4K1_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.61	703	436	26	3	671	5	640	6e-18	98.6
rs:WP_042743042	DNA topoisomerase III, partial [Staphylococcus aureus].	34.08	179	111	3	52	223	2	180	6e-18	94.0
rs:WP_014124944	DNA topoisomerase I [Tetragenococcus halophilus].	24.62	585	364	23	90	635	68	614	6e-18	98.6
rs:WP_029238067	DNA topoisomerase I [Streptococcus sobrinus].	23.10	580	372	20	83	629	87	625	6e-18	98.6
tr:A0A0D3H8J7_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OBART09G15360.1};	23.53	408	270	12	191	586	1122	1499	6e-18	99.4
tr:F8WKE5_STAAU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:BAK53124.1};	34.08	179	111	3	52	223	2	180	6e-18	94.0
rs:WP_040843203	DNA topoisomerase I [Treponema saccharophilum].	24.56	566	363	19	83	618	84	615	6e-18	98.6
rs:WP_013575912	MULTISPECIES: topoisomerase I [Rahnella].	24.04	653	380	24	76	673	82	673	6e-18	99.0
rs:WP_010324337	topoisomerase I [Marinobacterium stanieri].	23.10	593	379	20	76	633	93	643	6e-18	99.0
rs:WP_020192583	topoisomerase I, partial [Pseudomonas putida].	24.58	476	299	14	186	633	195	638	6e-18	98.6
rs:WP_017909761	DNA topoisomerase I [Xanthomonas sp. SHU199].	25.00	580	333	21	3	538	5	526	6e-18	98.6
rs:WP_022082367	DNA topoisomerase III [Bacteroides sp. CAG:144].	29.05	296	160	12	378	630	2	290	6e-18	95.5
rs:WP_021458862	DNA topoisomerase I [Staphylococcus sp. EGD-HP3].	24.47	568	369	18	90	629	67	602	6e-18	98.6
rs:WP_013971714	MULTISPECIES: topoisomerase I [Pseudomonas].	24.37	476	300	14	186	633	195	638	6e-18	99.0
tr:A0A0A1MTC0_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.40	643	405	23	83	672	50	651	6e-18	98.6
tr:F5RLS8_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.11	675	412	23	3	636	19	627	6e-18	98.6
tr:A0A0C7C669_9FUNG	SubName: Full=RMATCC62417_13354 protein {ECO:0000313|EMBL:CEG78806.1};	22.17	636	407	23	83	672	50	643	6e-18	98.6
tr:A0A0B4BBE9_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.19	587	373	22	90	642	87	635	6e-18	98.6
tr:A0A078LGR5_CITKO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.75	602	377	23	73	633	74	634	6e-18	99.0
rs:WP_013820830	DNA topoisomerase I [Methylomonas methanica].	23.42	602	381	21	76	630	53	621	6e-18	98.6
rs:XP_007906923	PREDICTED: DNA topoisomerase 3-beta-1 [Callorhinchus milii].	23.85	629	392	23	3	585	5	592	6e-18	99.0
rs:WP_014159758	DNA topoisomerase I [Pseudoxanthomonas spadix].	23.78	572	350	18	3	538	5	526	6e-18	98.6
rs:WP_028597444	DNA topoisomerase I [Paenibacillus pasadenensis].	24.07	644	394	27	88	681	62	660	6e-18	98.6
rs:WP_021704046	DNA topoisomerase I [Vibrio proteolyticus].	25.08	626	351	22	57	633	85	641	6e-18	99.0
tr:F7JRC3_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGN34944.1};	34.43	183	112	4	497	673	14	194	6e-18	94.0
rs:WP_039669638	DNA topoisomerase I [Coxiella burnetii].	23.42	568	348	18	3	534	5	521	6e-18	98.6
tr:A0A0D6A3Q4_9LACO	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:BAQ57309.1};	23.86	591	371	23	83	635	71	620	6e-18	98.6
rs:WP_034811450	DNA topoisomerase I [[Eubacterium] sulci].	25.98	585	350	24	90	635	61	601	6e-18	98.6
rs:WP_031943336	Top: DNA topoisomerase [uncultured bacterium].	24.49	490	305	15	168	631	138	588	6e-18	98.2
rs:WP_008315788	DNA topoisomerase 1 [Wohlfahrtiimonas chitiniclastica].	24.24	561	350	17	3	534	5	519	6e-18	98.6
rs:WP_040948035	DNA topoisomerase I [Coxiella burnetii].	23.42	568	348	18	3	534	5	521	6e-18	98.6
rs:WP_002671672	DNA topoisomerase I [Treponema denticola].	25.05	543	337	22	163	675	157	659	6e-18	98.6
rs:WP_017796659	DNA topoisomerase I [Oceanobacillus kimchii].	24.47	568	357	22	105	635	82	614	6e-18	98.6
rs:WP_018416638	topoisomerase I [Teredinibacter turnerae].	24.26	606	373	22	65	629	80	640	6e-18	98.6
rs:WP_027205421	DNA topoisomerase I [Butyrivibrio fibrisolvens].	24.88	627	390	22	90	679	68	650	6e-18	98.6
rs:WP_007351952	topoisomerase I [Marinobacter sp. ELB17].	23.99	592	378	20	76	633	93	646	6e-18	98.6
rs:WP_028411437	MULTISPECIES: DNA topoisomerase I [Bacillus].	23.49	562	369	21	105	635	82	613	6e-18	98.6
rs:WP_044163613	DNA topoisomerase I [Bacteroides reticulotermitis].	26.00	473	294	14	74	526	51	487	6e-18	98.6
rs:WP_025223630	DNA topoisomerase I [Methylophilaceae bacterium 11].	24.20	657	389	25	2	614	3	594	6e-18	98.6
rs:WP_035685089	DNA topoisomerase I [Avibacterium paragallinarum].	24.90	482	290	17	187	633	196	640	6e-18	98.6
rs:WP_043102403	DNA topoisomerase I [Pseudomonas aeruginosa].	22.70	599	378	19	74	633	85	637	6e-18	98.6
rs:WP_035247162	DNA topoisomerase I [Alcanivorax jadensis].	24.02	483	297	17	186	631	200	649	6e-18	99.0
rs:WP_033659604	DNA topoisomerase, partial [Enterococcus faecium].	26.30	270	183	6	413	667	15	283	6e-18	95.1
rs:WP_033917940	DNA topoisomerase I [Enterococcus faecalis].	25.35	564	346	24	103	629	81	606	6e-18	98.2
rs:WP_011506859	topoisomerase I [Chromohalobacter salexigens].	24.26	610	384	21	61	633	76	644	6e-18	98.6
rs:WP_045162551	DNA topoisomerase I [Pseudomonas stutzeri].	22.90	594	383	15	74	633	84	636	6e-18	98.6
rs:WP_002121782	DNA topoisomerase I [Bacillus cereus].	23.39	560	372	20	105	635	82	613	6e-18	98.2
tr:S7N8C3_MYOBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.98	631	396	22	3	585	5	593	6e-18	99.0
rs:WP_011042034	topoisomerase I [Colwellia psychrerythraea].	23.36	608	377	21	65	629	75	636	6e-18	98.6
rs:WP_009302711	DNA topoisomerase I [Desulfovibrio sp. 6_1_46AFAA].	24.04	649	403	25	76	676	53	659	7e-18	98.6
rs:WP_040976355	DNA topoisomerase I [Pasteurella sp. FF6].	25.57	481	288	16	187	633	196	640	7e-18	98.6
rs:WP_002788527	DNA topoisomerase I [Microcystis aeruginosa].	25.37	611	350	22	3	560	4	561	7e-18	98.6
rs:XP_002834673	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Pongo abelii].	22.82	631	397	22	3	585	5	593	7e-18	98.6
rs:WP_034001363	DNA topoisomerase I [Pseudomonas aeruginosa].	22.54	599	379	19	74	633	85	637	7e-18	98.6
rs:WP_016485640	topoisomerase I [Pseudomonas putida].	24.43	483	291	15	186	633	195	638	7e-18	98.6
rs:WP_002595671	DNA topoisomerase I [[Clostridium] clostridioforme].	23.77	568	352	19	90	616	67	594	7e-18	98.2
rs:WP_011534822	topoisomerase I [Pseudomonas entomophila].	23.75	480	298	12	186	633	195	638	7e-18	98.6
rs:WP_013164497	DNA topoisomerase I [Desulfurivibrio alkaliphilus].	23.44	687	421	28	3	640	5	635	7e-18	98.6
tr:A0A0E0ILY8_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA09G16480.1};	23.17	410	269	13	191	586	1353	1730	7e-18	99.4
rs:WP_003081026	DNA topoisomerase I [Streptococcus macacae].	24.10	581	367	22	83	630	78	617	7e-18	98.2
rs:WP_028526255	DNA topoisomerase I [Runella limosa].	26.75	471	285	16	77	526	54	485	7e-18	98.6
rs:WP_046822586	DNA topoisomerase I [Clostridium sp. JC272].	24.61	573	340	26	103	631	81	605	7e-18	98.2
rs:WP_046406360	DNA topoisomerase I [Clostridium sp. A254.MGS-251].	24.42	692	392	30	2	637	3	619	7e-18	98.2
rs:XP_003493773	PREDICTED: DNA topoisomerase 3-beta-1 [Bombus impatiens].	20.83	677	451	20	3	630	5	645	7e-18	98.6
rs:WP_040981465	DNA topoisomerase I [Mesorhizobium plurifarium].	23.22	689	414	28	1	630	1	633	7e-18	98.6
rs:XP_010522285	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Tarenaya hassleriana].	24.16	505	328	17	105	586	55	527	7e-18	98.6
rs:XP_006358794	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X2 [Solanum tuberosum].	22.87	551	373	15	105	631	55	577	7e-18	98.6
rs:WP_013280745	DNA topoisomerase I [Butyrivibrio proteoclasticus].	24.73	562	350	20	90	616	75	598	7e-18	98.2
rs:WP_046792747	DNA topoisomerase I [Rhizobium sp. LC145].	22.79	667	407	26	32	630	10	636	7e-18	98.6
rs:WP_035603017	DNA topoisomerase I [Edwardsiella tarda].	23.81	525	321	16	187	673	190	673	7e-18	98.6
rs:XP_004742578	PREDICTED: DNA topoisomerase 3-beta-1 isoform X5 [Mustela putorius furo].	22.63	623	395	22	3	585	5	580	7e-18	98.6
rs:WP_027192232	DNA topoisomerase I [Desulfovibrio putealis].	22.89	603	387	16	76	640	53	615	7e-18	98.6
rs:WP_046355048	DNA topoisomerase I [Pseudoalteromonas luteoviolacea].	24.21	599	374	22	72	631	84	641	7e-18	98.6
tr:T0PKA2_9CLOT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.87	563	360	16	83	616	10	538	7e-18	98.2
rs:WP_029269775	DNA topoisomerase I [Virgibacillus alimentarius].	24.39	570	356	22	105	635	82	615	7e-18	98.2
rs:WP_019281959	topoisomerase I [Vibrio anguillarum].	25.05	511	299	16	163	633	174	640	7e-18	98.6
rs:XP_003359220	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Sus scrofa].	22.89	629	399	22	3	585	5	593	7e-18	98.6
rs:WP_033996124	DNA topoisomerase I [Pseudomonas aeruginosa].	22.54	599	379	19	74	633	85	637	7e-18	98.6
rs:WP_023557169	DNA topoisomerase I [Brevibacillus panacihumi].	23.26	559	366	21	103	630	80	606	7e-18	98.2
rs:WP_019173403	DNA topoisomerase I [Pseudaminobacter salicylatoxidans].	22.40	701	405	27	1	630	1	633	7e-18	98.6
rs:WP_018704265	hypothetical protein [Anaeromusa acidaminophila].	24.64	491	294	17	187	636	161	616	7e-18	98.2
rs:WP_027937588	DNA topoisomerase I [Anaeroarcus burkinensis].	24.64	491	294	17	187	636	161	616	7e-18	98.2
rs:WP_010785477	DNA topoisomerase 1 [Enterococcus faecalis].	25.35	564	346	24	103	629	81	606	7e-18	98.2
tr:E3EPR8_BIFBS	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ADO52605.1};	30.04	243	145	5	457	677	95	334	7e-18	95.9
rs:WP_007119147	DNA topoisomerase I [Oceanibulbus indolifex].	24.64	560	342	18	1	534	1	506	7e-18	98.6
rs:WP_041069001	DNA topoisomerase I [Pseudomonas sp. W15Feb9B].	23.65	592	381	20	74	633	87	639	7e-18	98.6
tr:K1Y7J1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.68	666	391	30	3	629	5	605	7e-18	98.2
rs:WP_036258330	DNA topoisomerase I, partial [Mesorhizobium sp. WSM3224].	22.71	700	404	25	1	630	1	633	7e-18	98.6
rs:XP_010380071	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Rhinopithecus roxellana].	22.82	631	397	22	3	585	5	593	7e-18	98.6
rs:WP_028877668	DNA topoisomerase I [Teredinibacter turnerae].	23.47	605	379	20	65	629	80	640	7e-18	98.6
rs:WP_038922768	DNA topoisomerase I [Dickeya dadantii].	23.54	650	391	22	75	673	81	675	7e-18	98.6
rs:WP_036885723	DNA topoisomerase I [Prevotella melaninogenica].	24.18	608	355	22	3	578	5	538	7e-18	98.6
rs:WP_045052677	DNA topoisomerase I [Chroococcales cyanobacterium CENA595].	23.36	625	373	18	3	574	4	575	7e-18	98.6
tr:A0A015QWY1_BACFG	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EXY29863.1};	28.17	213	126	7	470	680	153	340	7e-18	95.9
gpu:CP010904_865	DNA topoisomerase 1 [Verrucomicrobia bacterium L21-Fru-AB]	23.95	622	362	22	3	572	5	567	7e-18	98.6
rs:WP_029834336	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	23.25	615	376	20	57	633	13	569	7e-18	98.6
rs:WP_011413890	DNA topoisomerase I [Erythrobacter litoralis].	23.10	684	407	27	1	629	1	620	7e-18	98.6
rs:WP_045778769	DNA topoisomerase I [Methylococcaceae bacterium Sn10-6].	24.39	570	340	24	3	534	5	521	7e-18	98.2
rs:WP_046155113	DNA topoisomerase I [Citrobacter freundii].	23.48	592	391	19	73	633	74	634	7e-18	98.6
rs:WP_002952806	DNA topoisomerase 1 [Salmonella enterica].	23.95	597	382	20	73	633	74	634	7e-18	98.6
rs:XP_004628014	PREDICTED: DNA topoisomerase 3-beta-1 [Octodon degus].	23.06	633	393	23	3	585	5	593	7e-18	98.6
rs:WP_036983237	DNA topoisomerase I [Providencia alcalifaciens].	23.33	493	308	14	168	631	138	589	7e-18	98.2
rs:WP_024237790	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	7e-18	98.6
rs:WP_046920631	DNA topoisomerase I [Lactobacillus ruminis].	23.89	586	376	21	90	642	87	635	7e-18	98.2
rs:WP_043865257	DNA topoisomerase I [Enterobacter aerogenes].	24.30	605	370	21	73	633	77	637	7e-18	98.6
tr:D1J990_9ARCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.08	662	420	27	1	629	1	619	7e-18	98.2
rs:WP_018883417	MULTISPECIES: DNA topoisomerase I [Paenibacillus].	24.20	566	367	20	103	636	80	615	7e-18	98.2
rs:WP_007622319	DNA topoisomerase I [Glaciecola arctica].	25.04	607	370	23	65	629	75	638	7e-18	98.6
rs:WP_002809370	DNA topoisomerase I [Xanthomonas fragariae].	23.95	572	349	18	3	538	5	526	7e-18	98.6
rs:WP_002437344	topoisomerase I [Escherichia hermannii].	24.30	605	370	21	73	633	77	637	7e-18	98.6
rs:WP_026704084	DNA topoisomerase I [Flavobacterium soli].	25.71	529	327	19	3	521	5	477	8e-18	98.6
tr:D6TIW6_9CHLR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.88	690	413	24	2	630	4	628	8e-18	98.6
rs:WP_006718217	topoisomerase I [Aggregatibacter segnis].	24.00	475	303	11	187	633	196	640	8e-18	98.6
tr:L1MTZ4_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EKX94520.1};	31.98	222	137	7	456	673	63	274	8e-18	95.1
rs:WP_013437787	MULTISPECIES: DNA topoisomerase I [Lactobacillus].	24.56	566	358	22	103	635	93	622	8e-18	98.2
tr:A0A0E0QTB8_ORYRU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ORUFI09G16580.1};	23.53	408	270	12	191	586	1347	1724	8e-18	99.0
rs:WP_024038270	DNA topoisomerase [Intestinibacter bartlettii].	25.13	569	338	23	103	629	81	603	8e-18	98.2
rs:WP_044941940	DNA topoisomerase I [Flavonifractor plautii].	22.60	562	374	18	83	614	61	591	8e-18	98.2
rs:WP_006474388	DNA topoisomerase I [endosymbiont of Tevnia jerichonana].	24.26	573	340	22	1	534	1	518	8e-18	98.2
rs:WP_036557354	DNA topoisomerase I [Oceanicola sp. MCTG156(1a)].	23.50	600	383	18	77	629	52	622	8e-18	98.6
rs:WP_034084293	DNA topoisomerase 1 [Pseudomonas aeruginosa].	22.54	599	379	19	74	633	85	637	8e-18	98.6
rs:WP_001701436	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	23.91	573	373	19	90	633	10	548	8e-18	98.2
tr:H7ENR1_9SPIO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.56	566	363	19	83	618	99	630	8e-18	98.2
tr:K2B533_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.38	680	406	26	3	630	5	621	8e-18	98.2
rs:WP_040394655	DNA topoisomerase I [Centipeda periodontii].	23.11	675	412	23	3	636	32	640	8e-18	98.2
tr:J6XCP6_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJX43731.1}; Flags: Fragment;	26.30	270	183	6	413	667	16	284	8e-18	95.1
rs:WP_022127786	DNA topoisomerase [Ruminococcus sp. CAG:579].	23.63	567	356	18	103	629	79	608	8e-18	98.2
rs:WP_035439122	DNA topoisomerase III, partial [Bacillus sp. RP1137].	25.59	340	224	11	358	675	1	333	8e-18	95.5
rs:WP_022207783	DNA topoisomerase [Eubacterium sp. CAG:252].	25.74	575	340	22	83	616	60	588	8e-18	98.2
rs:WP_020959337	DNA topoisomerase I [Geobacillus sp. JF8].	25.15	505	317	19	157	630	132	606	8e-18	98.2
rs:WP_027482820	DNA topoisomerase I [Deinococcus pimensis].	25.13	561	349	20	3	533	4	523	8e-18	98.2
rs:WP_012777656	DNA topoisomerase I [Methylotenera mobilis].	24.17	662	383	25	2	614	3	594	8e-18	98.6
rs:WP_008230948	DNA topoisomerase I [Roseobacter sp. CCS2].	22.08	684	417	25	1	629	1	623	8e-18	98.6
rs:XP_002099887	GE16470 [Drosophila yakuba].	24.73	461	300	15	188	630	211	642	8e-18	98.6
rs:WP_005958225	DNA topoisomerase I [Fusobacterium necrophorum].	26.79	601	322	24	3	561	6	530	8e-18	98.2
rs:WP_002844064	DNA topoisomerase I [Peptostreptococcus anaerobius].	25.33	675	389	33	3	634	5	607	8e-18	98.2
rs:WP_041990434	DNA topoisomerase I [Capnocytophaga cynodegmi].	25.19	532	326	15	3	521	5	477	8e-18	98.2
rs:WP_044736906	DNA topoisomerase I [Geobacillus kaustophilus].	24.80	504	320	17	157	630	132	606	8e-18	98.2
sp:TOP1_XYLFA	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.08	573	347	20	3	538	5	526	8e-18	98.2
rs:WP_005964300	DNA topoisomerase I [endosymbiont of Riftia pachyptila].	24.26	573	340	22	1	534	1	518	8e-18	98.2
rs:XP_008140862	PREDICTED: DNA topoisomerase 3-beta-1 [Eptesicus fuscus].	22.82	631	397	22	3	585	5	593	8e-18	98.6
tr:B3V6G7_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.58	344	214	10	3	321	19	345	8e-18	95.5
rs:WP_005824022	topoisomerase I [Actinobacillus minor].	23.79	601	366	22	74	631	87	638	8e-18	98.6
tr:A0A031G011_9PSED	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.35	591	384	19	74	633	87	639	8e-18	98.6
rs:WP_031806109	DNA topoisomerase I [Pseudomonas aeruginosa].	22.54	599	379	19	74	633	85	637	8e-18	98.6
rs:WP_020858636	DNA topoisomerase I [SAR86 cluster bacterium SAR86B].	24.23	582	361	20	72	622	80	612	8e-18	98.6
rs:WP_033892277	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	22.54	599	379	19	74	633	40	592	8e-18	98.2
rs:WP_044710918	DNA topoisomerase I, partial [Citrobacter freundii].	23.48	592	391	19	73	633	74	634	8e-18	98.2
rs:WP_005974558	DNA topoisomerase I [Fusobacterium periodonticum].	24.96	617	376	21	2	589	12	570	8e-18	98.2
rs:WP_002357484	MULTISPECIES: DNA topoisomerase I [Enterococcus].	25.35	564	346	24	103	629	81	606	8e-18	98.2
rs:XP_009057639	hypothetical protein LOTGIDRAFT_217319 [Lottia gigantea].	21.92	634	431	18	3	601	5	609	8e-18	98.2
rs:WP_047295278	DNA topoisomerase I [Pseudomonas fluorescens].	23.65	592	381	20	74	633	87	639	8e-18	98.2
tr:X8K7D9_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.15	672	395	28	3	635	22	624	8e-18	98.2
rs:WP_016714898	topoisomerase I [Pseudomonas monteilii].	24.95	477	296	15	186	633	195	638	8e-18	98.2
rs:WP_002997891	DNA topoisomerase I [Streptococcus downei].	22.93	580	373	20	83	629	87	625	8e-18	98.2
rs:WP_020000196	MULTISPECIES: DNA topoisomerase I [Desulfovibrio].	25.65	620	364	28	74	640	51	626	8e-18	98.2
rs:WP_038880283	DNA topoisomerase I [Cronobacter sakazakii].	24.01	604	373	25	73	633	4	564	8e-18	98.2
rs:WP_041080448	DNA topoisomerase I [Staphylococcus saprophyticus].	24.42	557	357	18	103	629	80	602	8e-18	98.2
rs:WP_046327098	DNA topoisomerase I [Lactobacillus helsingborgensis].	24.69	559	352	21	103	629	89	610	8e-18	98.2
rs:WP_033952254	DNA topoisomerase 1 [Pseudomonas aeruginosa].	22.54	599	379	19	74	633	85	637	8e-18	98.2
sp:TOP1_PSEAE	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	22.54	599	379	19	74	633	85	637	8e-18	98.2
rs:WP_013146985	DNA topoisomerase I [Methylotenera versatilis].	23.94	660	387	25	2	614	3	594	8e-18	98.2
rs:WP_035125554	DNA topoisomerase I [Flavobacterium aquatile].	24.42	647	403	26	3	618	5	596	8e-18	98.2
rs:WP_011421751	DNA topoisomerase I [Anaeromyxobacter dehalogenans].	23.61	631	388	24	76	646	97	693	8e-18	98.2
tr:E9CLX8_9ENTR	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:EFW12444.1}; Flags: Fragment;	29.31	232	142	6	1	221	118	338	8e-18	95.1
rs:WP_002381874	DNA topoisomerase I [Enterococcus faecalis].	25.35	564	346	24	103	629	81	606	8e-18	98.2
rs:WP_031685624	DNA topoisomerase I [Pseudomonas aeruginosa].	22.54	599	379	19	74	633	85	637	8e-18	98.2
rs:WP_022792758	DNA topoisomerase I [Marinococcus halotolerans].	22.74	554	370	17	105	629	82	606	8e-18	98.2
rs:WP_035316934	DNA topoisomerase I [Clostridium sp. MSTE9].	22.60	655	400	22	2	616	12	599	8e-18	98.2
rs:WP_015262991	DNA topoisomerase I [Desulfitobacterium dichloroeliminans].	22.21	698	417	22	3	629	5	647	8e-18	98.2
rs:WP_038860066	DNA topoisomerase I [Cronobacter sakazakii].	24.38	480	295	18	187	633	191	635	8e-18	98.2
tr:A0A090T1A0_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	24.43	479	295	13	187	633	7	450	8e-18	97.8
rs:WP_021707641	DNA topoisomerase I [Vibrio alginolyticus].	23.30	588	389	16	75	633	86	640	8e-18	98.2
rs:WP_019819801	hypothetical protein, partial [Vibrio splendidus].	32.99	197	117	5	186	367	8	204	8e-18	93.6
rs:WP_025317066	DNA topoisomerase I [Spiroplasma mirum].	25.13	593	374	19	77	643	56	604	8e-18	97.8
rs:WP_015365079	MULTISPECIES: DNA topoisomerase I [Staphylococcus].	23.92	556	362	20	103	629	80	603	8e-18	97.8
rs:WP_025754460	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	24.95	477	296	15	186	633	195	638	8e-18	98.2
rs:WP_031410440	DNA topoisomerase I [Geobacillus vulcani].	24.50	502	324	16	157	630	132	606	9e-18	97.8
rs:WP_021265626	DNA topoisomerase I [Salmonella enterica].	23.33	493	308	14	168	631	138	589	9e-18	97.8
rs:WP_033987437	DNA topoisomerase 1 [Pseudomonas aeruginosa].	22.54	599	379	19	74	633	85	637	9e-18	98.2
rs:WP_045108467	DNA topoisomerase I [Pseudomonas sp. HMSC05H02].	22.54	599	379	19	74	633	85	637	9e-18	98.2
tr:E2ZN61_9FIRM	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EFQ05383.1}; Flags: Fragment;	34.81	135	80	4	30	159	13	144	9e-18	91.7
rs:WP_044547706	DNA topoisomerase I, partial [Parabacteroides distasonis].	30.63	222	142	7	459	677	1	213	9e-18	93.6
rs:WP_034069888	DNA topoisomerase 1 [Pseudomonas aeruginosa].	22.54	599	379	19	74	633	85	637	9e-18	98.2
rs:WP_005933787	DNA topoisomerase III [Faecalibacterium prausnitzii].	40.34	119	63	3	3	118	15	128	9e-18	92.0
tr:C6L9V4_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.20	556	365	17	90	616	75	597	9e-18	97.8
rs:WP_017011370	topoisomerase I [Enterovibrio calviensis].	25.29	609	351	21	74	633	86	639	9e-18	98.2
rs:WP_026508777	DNA topoisomerase I [Butyrivibrio sp. MC2013].	23.58	564	354	20	90	616	69	592	9e-18	97.8
rs:WP_034033495	DNA topoisomerase I [Pseudomonas aeruginosa].	22.54	599	379	19	74	633	85	637	9e-18	98.2
tr:V5TZ61_CROSK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.01	604	373	25	73	633	88	648	9e-18	98.2
tr:U5UP87_9STAP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.92	556	362	20	103	629	37	560	9e-18	97.8
rs:WP_033950115	DNA topoisomerase I [Pseudomonas aeruginosa].	22.54	599	379	19	74	633	73	625	9e-18	98.2
rs:WP_029090988	DNA topoisomerase I [Brochothrix thermosphacta].	23.49	562	359	21	103	629	80	605	9e-18	97.8
rs:WP_036751414	DNA topoisomerase I [Paracoccus versutus].	22.84	705	416	30	1	648	1	634	9e-18	98.2
rs:WP_039646065	DNA topoisomerase I [Staphylococcus hyicus].	23.14	566	380	19	90	629	67	603	9e-18	97.8
rs:WP_013897831	DNA topoisomerase [Methanosalsum zhilinae].	24.00	625	380	23	3	580	4	580	9e-18	98.2
rs:WP_043038965	DNA topoisomerase I [Streptococcus equi].	23.97	559	355	21	103	630	104	623	9e-18	97.8
rs:WP_036140441	DNA topoisomerase I, partial [Lysobacter daejeonensis].	22.92	576	356	19	3	538	5	532	9e-18	98.2
rs:WP_046497361	DNA topoisomerase I [Syntrophomonas zehnderi].	24.60	626	381	24	90	675	68	642	9e-18	97.8
rs:WP_008683354	DNA topoisomerase I [Desulfovibrio sp. 3_1_syn3].	24.04	649	403	25	76	676	53	659	9e-18	98.2
tr:W2TUU8_NECAM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.48	494	302	15	112	564	154	612	9e-18	98.2
rs:WP_029570068	DNA topoisomerase I [Pantoea ananatis].	23.28	597	379	21	75	633	79	634	9e-18	98.2
rs:WP_038272057	DNA topoisomerase I [Xylella fastidiosa].	24.52	575	342	20	3	538	5	526	9e-18	98.2
rs:WP_016745005	DNA topoisomerase I, partial [Sphingomonas wittichii].	22.65	724	458	28	1	675	1	671	9e-18	97.8
rs:WP_036609379	MULTISPECIES: DNA topoisomerase I [Paenibacillus].	24.56	566	365	22	103	636	80	615	9e-18	97.8
rs:WP_044912601	DNA topoisomerase I [Butyrivibrio sp. WCE2006].	24.50	555	359	17	90	616	70	592	9e-18	97.8
tr:A0A0D6NX78_9PROT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAN70737.1};	23.51	638	393	28	55	629	28	633	9e-18	98.2
gp:CP007493_220	DNA topoisomerase I [Thermofilum carboxyditrophus 1505]	23.38	616	399	22	3	583	6	583	9e-18	97.8
rs:WP_046159897	DNA topoisomerase I [Caldanaerobacter subterraneus].	23.79	580	364	20	90	629	67	608	9e-18	97.8
rs:WP_017274264	DNA topoisomerase I [Sinorhizobium meliloti].	22.56	687	419	25	1	630	1	631	9e-18	98.2
rs:XP_007490460	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Monodelphis domestica].	22.70	630	399	23	3	585	5	593	9e-18	98.2
rs:WP_032983347	MULTISPECIES: DNA topoisomerase I [Cronobacter].	23.87	599	380	22	73	633	74	634	9e-18	98.2
rs:WP_008807785	MULTISPECIES: topoisomerase I [Klebsiella].	23.06	607	384	19	60	633	78	634	9e-18	98.2
rs:WP_029377477	DNA topoisomerase I [Staphylococcus xylosus].	23.27	550	372	18	103	629	80	602	9e-18	97.8
rs:WP_012271345	topoisomerase I [Pseudomonas putida].	24.37	476	300	14	186	633	195	638	9e-18	98.2
rs:WP_012676889	DNA topoisomerase I [Persephonella marina].	25.18	552	341	19	2	537	8	503	9e-18	97.8
rs:WP_033008161	MULTISPECIES: DNA topoisomerase I [Bacillaceae].	24.21	504	323	17	157	630	132	606	9e-18	97.8
rs:WP_033016014	DNA topoisomerase I [Geobacillus stearothermophilus].	24.21	504	323	17	157	630	132	606	9e-18	97.8
rs:WP_017820029	topoisomerase I [Vibrio alginolyticus].	23.30	588	389	16	75	633	86	640	9e-18	98.2
rs:WP_009064086	DNA topoisomerase I [Clostridium sp. JCD].	22.53	648	409	21	2	616	3	590	9e-18	97.8
rs:WP_044593861	DNA topoisomerase I [Cronobacter sakazakii].	24.01	604	373	25	73	633	74	634	9e-18	98.2
rs:WP_014794888	MULTISPECIES: DNA topoisomerase I [Desulfitobacterium].	22.88	708	435	28	3	671	5	640	9e-18	97.8
rs:WP_034052320	DNA topoisomerase I [Pseudomonas aeruginosa].	22.54	599	379	19	74	633	85	637	9e-18	98.2
rs:WP_038229594	DNA topoisomerase I [Vibrio sp. ER1A].	24.25	602	370	18	73	633	83	639	1e-17	98.2
rs:WP_034024827	DNA topoisomerase 1 [Pseudomonas aeruginosa].	22.54	599	379	19	74	633	85	637	1e-17	98.2
rs:WP_009404616	DNA topoisomerase I subunit omega [Pseudomonas putida].	23.54	480	297	13	187	633	196	638	1e-17	98.2
rs:WP_025338324	DNA topoisomerase I [Pseudomonas sp. FGI182].	24.37	476	300	14	186	633	195	638	1e-17	98.2
rs:WP_021671624	DNA topoisomerase I [Prevotella sp. F0091].	24.34	608	354	22	3	578	5	538	1e-17	98.2
tr:K8D9X4_CROSK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.87	599	380	22	73	633	72	632	1e-17	98.2
rs:WP_006962916	topoisomerase I [Vibrio coralliilyticus].	23.95	593	379	16	75	633	85	639	1e-17	98.2
rs:WP_004387669	topoisomerase I [Cronobacter sakazakii].	23.87	599	380	22	73	633	74	634	1e-17	98.2
rs:WP_012290577	DNA topoisomerase I [Finegoldia magna].	23.81	651	390	27	2	616	5	585	1e-17	97.8
gpu:CP011047_2854	DNA topoisomerase I [Cronobacter sakazakii]	24.01	604	373	25	73	633	88	648	1e-17	98.2
rs:XP_012321897	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Aotus nancymaae].	22.70	630	400	21	3	585	5	594	1e-17	98.2
tr:N1ZMY9_9CLOT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.69	612	360	25	90	630	82	657	1e-17	97.8
tr:D3I2I7_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.18	608	355	22	3	578	7	540	1e-17	97.8
rs:WP_004991834	topoisomerase I [Shigella boydii].	23.79	601	378	24	73	633	74	634	1e-17	98.2
rs:WP_041460856	DNA topoisomerase I [Cronobacter sakazakii].	23.87	599	380	22	73	633	74	634	1e-17	98.2
rs:WP_039978511	DNA topoisomerase I [Shewanella decolorationis].	23.60	483	294	16	186	631	197	641	1e-17	98.2
rs:WP_035295700	DNA topoisomerase I [Clostridium sp. ASF356].	24.07	619	383	25	90	671	76	644	1e-17	97.8
rs:WP_016185340	DNA topoisomerase I [Enterococcus sulfureus].	24.27	585	366	22	90	635	68	614	1e-17	97.8
gp:CP003312_1799	DNA topoisomerase I [Cronobacter sakazakii ES15]	24.01	604	373	25	73	633	88	648	1e-17	98.2
rs:WP_040781672	DNA topoisomerase I, partial [Marvinbryantia formatexigens].	23.20	556	365	17	90	616	67	589	1e-17	97.8
rs:WP_044175108	DNA topoisomerase I [Enterobacter massiliensis].	23.75	480	298	17	187	633	190	634	1e-17	98.2
rs:WP_012542049	topoisomerase I [Klebsiella pneumoniae].	23.06	607	384	19	60	633	78	634	1e-17	98.2
rs:WP_019039527	DNA topoisomerase I [Psychroflexus tropicus].	24.52	620	378	21	3	601	5	555	1e-17	98.2
rs:WP_024809418	DNA topoisomerase I [Oceanicola sp. HL-35].	22.16	704	450	23	1	659	1	651	1e-17	98.2
rs:WP_005697517	topoisomerase I [Haemophilus parainfluenzae].	23.62	597	381	19	73	633	83	640	1e-17	98.2
rs:WP_032971091	DNA topoisomerase I [Cronobacter malonaticus].	23.87	599	380	22	73	633	74	634	1e-17	98.2
rs:WP_043008734	DNA topoisomerase I [Vibrio coralliilyticus].	23.95	593	379	16	75	633	85	639	1e-17	98.2
rs:WP_005390711	MULTISPECIES: topoisomerase I [Vibrio].	23.30	588	389	16	75	633	86	640	1e-17	98.2
rs:WP_005378351	MULTISPECIES: topoisomerase I [Vibrio].	23.30	588	389	16	75	633	86	640	1e-17	98.2
rs:WP_031372129	DNA topoisomerase I [Lysobacter antibioticus].	23.83	579	341	19	3	538	5	526	1e-17	98.2
rs:WP_021983662	GTP-sensing transcriptional pleiotropic repressor CodY [Eubacterium sp. CAG:603].	24.46	556	333	21	103	616	80	590	1e-17	97.8
rs:WP_027313742	DNA topoisomerase I [Balneatrix alpica].	23.64	588	373	21	76	629	93	638	1e-17	98.2
rs:WP_045152232	DNA topoisomerase III, partial [Escherichia coli].	25.82	395	220	12	349	673	38	429	1e-17	96.3
rs:WP_023155299	DNA topoisomerase I [Escherichia coli].	23.96	601	377	24	73	633	74	634	1e-17	98.2
rs:WP_021919504	DNA topoisomerase [Firmicutes bacterium CAG:114].	23.39	560	362	15	90	616	69	594	1e-17	97.8
rs:WP_028870147	DNA topoisomerase I [Psychromonas arctica].	26.65	499	298	21	168	633	180	643	1e-17	98.2
rs:WP_004141651	DNA topoisomerase I [Cardiobacterium hominis].	24.43	573	325	19	3	534	5	510	1e-17	97.8
rs:XP_002743624	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Callithrix jacchus].	22.73	629	400	21	3	585	5	593	1e-17	98.2
rs:XP_006908726	PREDICTED: DNA topoisomerase 3-beta-1 [Pteropus alecto].	22.50	631	399	21	3	585	5	593	1e-17	98.2
rs:WP_012905972	topoisomerase I [Citrobacter rodentium].	23.40	594	389	18	73	633	74	634	1e-17	98.2
rs:WP_033700418	DNA topoisomerase I [Pseudomonas sp. WCS358].	24.37	476	300	14	186	633	195	638	1e-17	98.2
tr:A0A022RN26_ERYGU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.57	645	402	25	32	618	186	797	1e-17	98.2
tr:K8C0K8_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.01	604	373	25	73	633	88	648	1e-17	98.2
rs:WP_043592348	DNA topoisomerase I [Chromobacterium haemolyticum].	22.79	667	417	22	3	630	5	612	1e-17	97.8
rs:WP_009096324	topoisomerase I [Halomonas sp. GFAJ-1].	25.55	595	360	21	76	633	94	642	1e-17	98.2
rs:WP_021997276	DNA topoisomerase [Ruminococcus sp. CAG:724].	24.40	582	369	18	83	629	59	604	1e-17	97.8
rs:WP_031656455	DNA topoisomerase I [Pseudomonas aeruginosa].	22.54	599	379	19	74	633	85	637	1e-17	98.2
tr:V1DHE5_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.60	483	294	16	186	631	213	657	1e-17	98.2
rs:WP_020008659	DNA topoisomerase I [Salinicoccus albus].	23.21	560	367	21	100	629	77	603	1e-17	97.8
rs:WP_018280051	DNA topoisomerase I [Capnocytophaga cynodegmi].	25.00	532	327	15	3	521	5	477	1e-17	97.8
rs:WP_041008850	DNA topoisomerase I [Mesorhizobium plurifarium].	23.22	689	414	28	1	630	1	633	1e-17	98.2
tr:C2CGU5_9FIRM	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EEI83209.1};	37.40	131	70	4	1	126	1	124	1e-17	90.9
rs:WP_032820860	topoisomerase I, partial [Oenococcus oeni].	26.97	241	154	5	261	489	9	239	1e-17	94.0
rs:WP_041909636	hypothetical protein, partial [Candidatus Iainarchaeum andersonii].	23.01	678	439	26	1	640	1	633	1e-17	97.4
rs:WP_032992965	DNA topoisomerase I [Cronobacter malonaticus].	23.87	599	380	22	73	633	74	634	1e-17	98.2
rs:XP_005636691	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Canis lupus familiaris].	22.50	631	399	22	3	585	5	593	1e-17	97.8
rs:WP_044877604	DNA topoisomerase I [Paenibacillus sp. IHBB 10380].	24.92	594	362	29	88	636	62	616	1e-17	97.8
rs:WP_018163831	DNA topoisomerase I [Streptococcus henryi].	22.94	558	362	21	103	630	100	619	1e-17	97.8
rs:WP_019518815	topoisomerase I [Moraxella boevrei].	24.87	599	358	21	75	629	115	665	1e-17	98.2
rs:XP_001978430	GG17682 [Drosophila erecta].	24.44	495	317	17	188	655	211	675	1e-17	98.2
rs:WP_023810547	DNA topoisomerase I [Mesorhizobium sp. L2C084A000].	22.71	700	404	24	1	630	1	633	1e-17	98.2
rs:WP_046464367	DNA topoisomerase I [Staphylococcus warneri].	23.92	556	362	20	103	629	80	603	1e-17	97.8
rs:WP_019277761	topoisomerase I [Vibrio coralliilyticus].	23.95	593	379	16	75	633	85	639	1e-17	98.2
tr:L1PYG3_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.27	585	339	21	95	629	138	668	1e-17	97.8
rs:WP_040736674	DNA topoisomerase I [Paenibacillus alvei].	23.85	566	369	20	103	636	80	615	1e-17	97.8
rs:WP_004341311	MULTISPECIES: DNA topoisomerase I [Prevotella].	23.83	600	366	18	3	580	5	535	1e-17	97.8
tr:S6ULM2_PSESF	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EPN39347.1};	29.19	185	124	3	1	184	1	179	1e-17	93.2
rs:WP_038132716	DNA topoisomerase I [Thioclava sp. DT23-4].	23.28	696	429	24	1	630	1	657	1e-17	98.2
rs:WP_010430824	topoisomerase I [Pseudomonas syringae].	23.82	592	380	20	74	633	87	639	1e-17	97.8
rs:WP_003417673	topoisomerase I [Pseudomonas syringae].	23.82	592	380	20	74	633	87	639	1e-17	97.8
rs:WP_005968475	DNA topoisomerase I [Fusobacterium periodonticum].	25.32	620	370	22	2	589	9	567	1e-17	97.8
rs:WP_027088939	DNA topoisomerase I [[Clostridium] saccharogumia].	24.53	644	381	25	2	611	4	576	1e-17	97.8
rs:WP_013406929	DNA topoisomerase I [Leadbetterella byssophila].	24.71	611	380	19	3	596	5	552	1e-17	97.8
rs:WP_039056062	DNA topoisomerase I [Enterobacter sp. Bisph1].	23.61	610	368	24	73	633	74	634	1e-17	97.8
rs:WP_018405529	topoisomerase I [Marinobacter lipolyticus].	23.65	592	380	20	76	633	93	646	1e-17	97.8
rs:WP_008430847	DNA topoisomerase I [Planococcus donghaensis].	23.16	557	368	18	103	630	80	605	1e-17	97.8
rs:WP_040948662	DNA topoisomerase I [Paenibacillaceae bacterium G5].	23.86	570	371	23	100	636	77	616	1e-17	97.8
rs:WP_038148787	DNA topoisomerase I [Veillonella atypica].	24.27	585	339	21	95	629	135	665	1e-17	97.8
rs:WP_029880927	MULTISPECIES: DNA topoisomerase I [Paenibacillus].	24.69	567	363	22	103	636	80	615	1e-17	97.8
rs:WP_040917580	DNA topoisomerase I [Leptospira meyeri].	23.66	541	348	11	87	596	48	554	1e-17	97.4
rs:WP_018972214	DNA topoisomerase I [Rudaea cellulosilytica].	23.69	574	348	19	3	538	5	526	1e-17	97.8
rs:WP_038640964	DNA topoisomerase I [Citrobacter freundii].	23.53	595	387	20	73	633	74	634	1e-17	97.8
rs:WP_020802463	DNA topoisomerase I [Klebsiella pneumoniae].	22.77	606	387	17	60	633	78	634	1e-17	97.8
rs:WP_014166394	DNA topoisomerase I [Flavobacterium columnare].	24.86	531	329	19	3	521	5	477	1e-17	97.8
gpu:CP009316_1	DNA topoisomerase family protein [Bacillus anthracis str. Turkey32]	27.95	297	205	8	385	675	1	294	1e-17	96.7
rs:WP_032257049	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	1e-17	97.8
gpu:CP011805_1000	DNA topoisomerase 1 [Altererythrobacter marensis]	21.92	689	409	28	1	629	1	620	1e-17	97.8
rs:WP_017805692	topoisomerase I [Avibacterium paragallinarum].	24.69	482	291	17	187	633	196	640	1e-17	97.8
rs:WP_033970640	DNA topoisomerase I [Pseudomonas aeruginosa].	22.54	599	379	19	74	633	85	637	1e-17	97.8
rs:WP_023114523	DNA topoisomerase 1 [Pseudomonas aeruginosa].	22.69	595	375	19	74	629	85	633	1e-17	97.8
rs:WP_002762074	DNA topoisomerase I [Microcystis aeruginosa].	25.86	611	347	23	3	560	4	561	1e-17	97.8
tr:K8D3D3_CROSK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.01	604	373	25	73	633	88	648	1e-17	97.8
rs:WP_008403299	DNA topoisomerase I [Bacillus isronensis].	23.62	563	358	16	103	629	80	606	1e-17	97.4
rs:WP_043121319	DNA topoisomerase I [Aeromonas hydrophila].	24.42	606	361	22	75	633	82	637	1e-17	97.8
rs:WP_005962844	DNA topoisomerase I [Fusobacterium necrophorum].	26.79	601	322	24	3	561	6	530	1e-17	97.8
rs:WP_002677701	DNA topoisomerase I [Treponema denticola].	24.82	544	337	21	163	675	157	659	1e-17	97.8
rs:WP_009104432	DNA topoisomerase I [Treponema sp. JC4].	23.20	582	376	18	83	630	69	613	1e-17	97.8
tr:E2SJG9_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.54	538	332	17	3	520	4	487	1e-17	97.8
tr:A0A0D1WU41_9EURO	SubName: Full=Exophiala sideris strain CBS 121828 unplaced genomic scaffold supercont1.3, whole genome shotgun sequence {ECO:0000313|EMBL:KIV78661.1};	22.63	632	405	20	3	584	7	604	1e-17	97.4
rs:XP_007973097	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Chlorocebus sabaeus].	23.33	630	395	23	3	585	5	593	1e-17	97.8
rs:WP_015481981	DNA topoisomerase I [Polaribacter sp. MED152].	25.61	535	320	18	3	521	5	477	1e-17	97.8
rs:WP_038156048	DNA topoisomerase I [Vibrio sp. B183].	23.95	593	379	16	75	633	85	639	1e-17	97.8
rs:WP_025730271	DNA topoisomerase I [Atopobacter phocae].	24.09	577	363	21	90	629	68	606	1e-17	97.4
rs:WP_020583560	hypothetical protein [Endozoicomonas elysicola].	24.59	614	369	24	65	633	80	644	1e-17	97.8
rs:WP_019622251	topoisomerase I [Amphritea japonica].	23.77	589	375	18	76	631	95	642	1e-17	97.8
rs:XP_008222783	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Prunus mume].	24.06	532	355	16	121	631	7	510	1e-17	97.8
rs:WP_041119071	DNA topoisomerase I [Enterococcus gallinarum].	25.70	572	348	24	103	635	81	614	1e-17	97.4
rs:WP_014824496	DNA topoisomerase I [Solibacillus silvestris].	23.62	563	358	16	103	629	80	606	1e-17	97.4
rs:WP_043752749	DNA topoisomerase I, partial [Thiorhodococcus sp. AK35].	23.41	675	415	27	1	630	1	618	1e-17	97.8
rs:XP_012061314	PREDICTED: DNA topoisomerase 3-beta-1 [Atta cephalotes].	21.21	646	428	17	3	601	5	616	1e-17	97.4
rs:WP_022072476	DNA topoisomerase [Clostridium bartlettii CAG:1329].	25.13	569	338	23	103	629	81	603	1e-17	97.4
rs:WP_011647269	MULTISPECIES: DNA topoisomerase I [Hyphomonas].	23.46	682	413	27	1	629	1	626	1e-17	97.8
rs:XP_012321900	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Aotus nancymaae].	22.73	629	400	21	3	585	5	593	1e-17	97.8
rs:WP_006812921	topoisomerase I [Providencia rustigianii].	23.12	597	380	16	74	633	87	641	1e-17	97.8
rs:WP_009628079	DNA topoisomerase I [Pseudanabaena biceps].	22.86	630	386	16	3	582	4	583	1e-17	97.8
rs:WP_025766918	DNA topoisomerase I [Vibrio parahaemolyticus].	23.30	588	389	16	75	633	86	640	1e-17	97.8
rs:XP_005636690	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Canis lupus familiaris].	22.50	631	399	22	3	585	5	593	1e-17	97.8
rs:WP_029604771	DNA topoisomerase I [Kozakia baliensis].	22.15	632	408	23	55	629	28	632	1e-17	97.8
rs:WP_006020922	DNA topoisomerase I [Afipia broomeae].	24.49	690	404	31	1	630	1	633	1e-17	97.8
tr:A0A068RD33_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.22	646	398	23	74	673	80	673	1e-17	97.8
rs:WP_042979410	DNA topoisomerase I [Bacillus mycoides].	23.21	560	373	20	105	635	82	613	1e-17	97.4
rs:WP_044345962	DNA topoisomerase III, partial [Pseudomonas meliae].	28.87	239	156	5	446	673	2	237	1e-17	94.0
rs:WP_010128307	topoisomerase I [Haemophilus sputorum].	23.42	585	384	19	74	629	87	636	1e-17	97.8
rs:WP_032851656	DNA topoisomerase I [Pasteurella multocida].	25.00	476	293	15	187	631	196	638	1e-17	97.8
rs:WP_022056000	DNA topoisomerase [Clostridium sp. CAG:167].	22.40	558	365	18	90	616	67	587	1e-17	97.4
rs:WP_006684311	topoisomerase I [Citrobacter youngae].	23.31	592	392	19	73	633	74	634	1e-17	97.8
rs:WP_011264301	topoisomerase I [Salmonella enterica].	24.08	598	380	21	73	633	74	634	1e-17	97.8
rs:WP_023246917	DNA topoisomerase I subunit omega [Salmonella enterica].	23.70	595	386	20	73	633	74	634	1e-17	97.8
rs:WP_012313561	topoisomerase I [Pseudomonas putida].	23.86	591	381	18	74	633	86	638	1e-17	97.8
rs:WP_020879642	DNA topoisomerase I [Desulfovibrio sp. X2].	23.27	649	416	25	76	672	53	671	1e-17	97.8
rs:WP_046269261	DNA topoisomerase I [Pseudomonas syringae].	23.82	592	380	20	74	633	87	639	1e-17	97.8
rs:WP_006588265	DNA topoisomerase I [Lactobacillus jensenii].	23.94	564	350	22	103	629	83	604	1e-17	97.4
rs:WP_026903078	DNA topoisomerase I [Pedobacter glucosidilyticus].	23.03	660	404	19	3	622	5	600	1e-17	97.8
rs:WP_027291047	DNA topoisomerase I [Rikenella microfusus].	23.69	536	335	16	3	520	5	484	1e-17	97.8
rs:WP_028236271	DNA topoisomerase I [Pseudobutyrivibrio sp. MD2005].	23.72	565	366	18	83	616	60	590	1e-17	97.4
rs:WP_038810540	DNA topoisomerase I [Peptoclostridium difficile].	25.14	720	410	33	3	675	5	642	1e-17	97.4
rs:WP_034220760	DNA topoisomerase I [Arenimonas donghaensis].	22.63	570	355	17	3	536	5	524	1e-17	97.8
rs:WP_028028949	DNA topoisomerase I [Gemmobacter nectariphilus].	22.94	680	415	24	1	630	1	621	1e-17	97.8
rs:WP_019470223	MULTISPECIES: topoisomerase I [Pseudomonas].	24.58	476	299	14	186	633	195	638	1e-17	97.8
rs:WP_017842229	DNA topoisomerase I [Methylomicrobium buryatense].	24.25	565	347	18	3	534	5	521	1e-17	97.8
rs:WP_046328999	DNA topoisomerase I [Sneathia sp. Sn35].	26.14	593	327	25	3	560	13	529	1e-17	97.8
rs:WP_019682694	topoisomerase I, partial [Pseudomonas aeruginosa].	22.54	599	379	19	74	633	85	637	1e-17	97.8
rs:WP_036573083	DNA topoisomerase I [Oceanobacillus picturae].	24.78	569	358	21	103	635	80	614	1e-17	97.4
rs:WP_008080426	topoisomerase I [Vibrio sinaloensis].	24.05	499	319	13	163	633	173	639	1e-17	97.8
rs:WP_002839112	DNA topoisomerase I [Finegoldia magna].	24.23	648	391	27	2	616	5	585	1e-17	97.4
rs:WP_007232724	topoisomerase I [gamma proteobacterium HTCC2207].	23.85	587	366	18	83	629	100	645	1e-17	97.8
rs:WP_042128949	DNA topoisomerase I [Paenibacillus sp. FSL R5-0345].	24.19	587	374	23	88	636	62	615	1e-17	97.4
tr:A0A093H5H3_STRCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.09	563	363	18	36	564	26	552	1e-17	97.8
rs:WP_003840713	MULTISPECIES: DNA topoisomerase I subunit omega [Enterobacteriaceae].	23.48	592	391	19	73	633	74	634	1e-17	97.8
rs:WP_027970598	DNA topoisomerase I [Streptococcus castoreus].	23.24	581	370	19	83	629	84	622	1e-17	97.4
rs:WP_025803824	DNA topoisomerase I [Campylobacter sp. CIT045].	24.95	533	339	20	77	578	50	552	1e-17	97.4
rs:WP_018993201	DNA topoisomerase I [Thioalkalivibrio sp. ALgr1].	23.40	564	352	18	3	534	5	520	1e-17	97.8
rs:WP_011609067	topoisomerase I [Histophilus somni].	24.38	480	295	16	187	633	196	640	1e-17	97.8
rs:WP_015257273	DNA topoisomerase I [Thioalkalivibrio nitratireducens].	23.31	519	333	15	55	534	29	521	1e-17	97.8
rs:WP_002450562	DNA topoisomerase I [Staphylococcus warneri].	23.92	556	362	20	103	629	80	603	1e-17	97.4
tr:T0EC08_CLOSO	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EPZ61178.1};	31.96	219	124	8	2	205	3	211	1e-17	93.2
rs:WP_027697125	DNA topoisomerase I [Vibrio litoralis].	24.90	502	301	17	168	633	178	639	1e-17	97.8
tr:A0A034TJM3_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.26	589	389	16	75	633	87	642	1e-17	97.8
tr:L8XD87_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.46	601	366	18	77	633	13	563	1e-17	97.8
rs:WP_002689561	DNA topoisomerase I [Treponema denticola].	24.73	546	335	22	163	675	157	659	1e-17	97.4
rs:WP_034789719	DNA topoisomerase I [Hyphomonas beringensis].	23.75	682	411	28	1	629	1	626	1e-17	97.8
rs:WP_045422306	DNA topoisomerase I [Vibrio jasicida].	25.15	513	296	17	163	633	174	640	1e-17	97.8
rs:WP_033599499	DNA topoisomerase I [Enterococcus faecalis].	25.35	564	346	24	103	629	81	606	1e-17	97.4
rs:WP_009579003	DNA topoisomerase I [Fulvivirga imtechensis].	25.09	534	324	19	3	520	5	478	1e-17	97.4
rs:WP_036724648	DNA topoisomerase I [Paenibacillus sp. FSL R7-277].	23.09	680	408	27	3	636	5	615	1e-17	97.4
rs:WP_035444428	DNA topoisomerase I [Asaia platycodi].	22.03	631	410	22	55	629	28	632	1e-17	97.8
rs:XP_005567913	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Macaca fascicularis].	22.82	631	397	22	3	585	5	593	1e-17	97.8
tr:A0A0C7BNT0_9FUNG	SubName: Full=RMATCC62417_08376 protein {ECO:0000313|EMBL:CEG72895.1};	21.52	762	459	30	3	672	7	721	1e-17	97.8
rs:WP_015050175	DNA topoisomerase I [Thermacetogenium phaeum].	22.74	563	356	17	88	614	62	581	1e-17	97.4
rs:WP_026487707	DNA topoisomerase I [Butyrivibrio sp. XBB1001].	24.55	558	356	19	90	616	61	584	1e-17	97.4
rs:WP_045493307	DNA topoisomerase I [Pseudomonas sp. StFLB209].	23.49	596	377	20	74	633	87	639	1e-17	97.8
rs:WP_005418793	topoisomerase I [Aliivibrio fischeri].	25.05	507	304	17	163	633	172	638	1e-17	97.8
rs:WP_004344384	DNA topoisomerase I [Prevotella buccae].	23.83	600	366	18	3	580	5	535	1e-17	97.4
rs:WP_014781568	DNA topoisomerase I [Aequorivita sublithincola].	26.35	554	336	18	3	539	5	503	1e-17	97.8
rs:WP_013025933	topoisomerase I [Pantoea ananatis].	23.28	597	379	21	75	633	79	634	1e-17	97.8
rs:WP_014391063	topoisomerase I [Pasteurella multocida].	25.00	476	293	15	187	631	196	638	1e-17	97.8
rs:WP_022065862	DNA topoisomerase [Klebsiella variicola CAG:634].	23.06	607	384	19	60	633	78	634	1e-17	97.8
rs:WP_002443101	topoisomerase I [Shimwellia blattae].	23.19	595	376	17	77	633	86	637	1e-17	97.8
tr:A0A0C7NVR5_9THEM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.09	578	347	20	76	616	90	618	1e-17	97.4
rs:XP_004276082	PREDICTED: DNA topoisomerase 3-beta-1 [Orcinus orca].	23.02	630	397	22	3	585	5	593	1e-17	97.8
rs:XP_008651687	PREDICTED: uncharacterized protein LOC100383032 isoform X1 [Zea mays].	24.05	528	333	20	119	614	11	502	1e-17	97.4
rs:WP_027052032	DNA topoisomerase I [Mesorhizobium loti].	21.86	700	410	23	1	630	1	633	1e-17	97.8
rs:WP_045062417	DNA topoisomerase I [Pseudomonas sp. ES3-33].	23.26	473	307	13	187	633	197	639	1e-17	97.8
rs:WP_022826790	DNA topoisomerase I [Flavobacterium antarcticum].	24.86	531	329	18	3	521	5	477	1e-17	97.8
tr:E7MZJ2_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.34	667	427	19	3	636	41	649	1e-17	97.4
rs:WP_005377513	DNA topoisomerase I [Veillonella atypica].	23.25	572	361	19	95	629	135	665	1e-17	97.4
rs:WP_011069349	topoisomerase I [Shigella flexneri].	23.67	600	380	23	73	633	74	634	1e-17	97.8
rs:WP_039679626	DNA topoisomerase I [Terrisporobacter othiniensis].	24.47	609	377	23	103	675	81	642	1e-17	97.4
rs:WP_002800297	DNA topoisomerase I [Microcystis aeruginosa].	25.37	611	350	23	3	560	4	561	1e-17	97.8
rs:WP_038705745	DNA topoisomerase I [Pseudomonas mosselii].	23.42	474	307	12	186	633	195	638	1e-17	97.8
tr:K4Z7C0_PAEAL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.85	566	369	20	103	636	50	585	1e-17	97.4
tr:A0A099ZL27_TINGU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.09	563	363	18	36	564	26	552	1e-17	97.4
rs:WP_016150334	DNA topoisomerase 1 [Citrobacter sp. KTE30].	23.48	592	391	19	73	633	74	634	1e-17	97.8
rs:WP_034622365	DNA topoisomerase I, partial [Desulfovermiculus halophilus].	24.63	678	401	30	3	639	5	613	1e-17	97.4
rs:WP_003126977	MULTISPECIES: DNA topoisomerase I [Enterococcus].	25.70	572	348	24	103	635	81	614	1e-17	97.4
rs:WP_021785427	MULTISPECIES: topoisomerase I [Pseudomonas putida group].	24.58	476	299	14	186	633	195	638	1e-17	97.8
rs:WP_004609725	DNA topoisomerase I [[Clostridium] spiroforme].	23.57	645	386	24	2	611	4	576	1e-17	97.4
rs:WP_039276197	DNA topoisomerase I [Pectobacterium carotovorum].	24.50	600	368	22	74	633	81	635	1e-17	97.8
rs:WP_002987636	MULTISPECIES: DNA topoisomerase I [Myroides].	26.18	531	322	18	3	521	5	477	1e-17	97.4
rs:XP_006110596	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X1 [Pelodiscus sinensis].	21.97	610	389	22	3	564	5	575	1e-17	97.4
rs:WP_041099958	DNA topoisomerase I [Bacillus badius].	23.65	554	367	17	105	630	82	607	1e-17	97.4
tr:R2AMY6_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOF89568.1};	28.70	230	148	6	453	667	1	229	1e-17	93.6
rs:WP_002780028	DNA topoisomerase 1 [Microcystis aeruginosa].	24.92	610	354	21	3	560	4	561	1e-17	97.8
tr:K7GCG7_PELSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.97	610	389	22	3	564	5	575	1e-17	97.4
rs:WP_021975896	DNA topoisomerase [Ruminococcus sp. CAG:17].	23.09	563	355	20	90	616	67	587	1e-17	97.4
rs:WP_039118730	DNA topoisomerase I [Flavobacterium sp. JRM].	25.70	533	322	21	3	521	5	477	1e-17	97.4
rs:WP_005224424	DNA topoisomerase I [Marichromatium purpuratum].	22.26	674	424	25	1	630	1	618	1e-17	97.4
rs:WP_016616347	DNA topoisomerase I [Enterococcus faecalis].	24.64	560	355	23	103	629	81	606	1e-17	97.4
rs:WP_028759719	DNA topoisomerase I [Shewanella putrefaciens].	24.17	480	293	17	187	631	198	641	1e-17	97.4
rs:WP_027270824	DNA topoisomerase I [Legionella sainthelensi].	25.04	627	383	29	55	630	29	619	1e-17	97.4
rs:WP_035537897	DNA topoisomerase I [Hyphomonas oceanitis].	23.75	682	411	28	1	629	1	626	1e-17	97.4
rs:WP_036767626	DNA topoisomerase I, partial [Peptostreptococcaceae bacterium VA2].	24.96	581	327	24	103	631	81	604	1e-17	97.1
tr:K1RLQ8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC46343.1}; Flags: Fragment;	33.50	203	122	5	475	671	4	199	1e-17	92.8
tr:F3GFX9_PSESJ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.82	592	380	20	74	633	87	639	1e-17	97.4
rs:WP_011909276	DNA topoisomerase I [Rhodobacter sphaeroides].	22.16	686	415	29	1	630	1	623	1e-17	97.4
rs:WP_012983639	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	23.40	564	352	18	3	534	5	520	1e-17	97.4
rs:WP_026985710	DNA topoisomerase I [Flavobacterium sp. URHB0058].	24.15	675	415	24	3	659	5	600	1e-17	97.4
tr:G5IUV3_9ENTE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.70	572	348	24	103	635	89	622	1e-17	97.4
rs:WP_013145765	DNA topoisomerase I [Geobacillus sp. C56-T3].	25.05	555	357	20	105	630	82	606	1e-17	97.4
rs:WP_005426314	topoisomerase I [Vibrio campbellii].	23.59	602	364	18	77	633	90	640	1e-17	97.4
rs:WP_046338444	DNA topoisomerase I [Pasteurella multocida].	23.62	597	377	17	74	633	86	640	1e-17	97.4
rs:XP_009619602	PREDICTED: DNA topoisomerase 3-beta isoform X3 [Nicotiana tomentosiformis].	22.56	523	358	13	129	631	82	577	1e-17	97.4
rs:XP_005834439	hypothetical protein GUITHDRAFT_69656 [Guillardia theta CCMP2712].	23.06	607	362	22	3	546	5	569	1e-17	97.4
rs:WP_012533245	topoisomerase I [Aliivibrio fischeri].	25.05	507	304	17	163	633	172	638	1e-17	97.4
rs:WP_034580483	DNA topoisomerase I [Clostridium acetobutylicum].	24.55	550	338	17	103	616	80	588	1e-17	97.4
rs:NP_001253336	DNA topoisomerase 3-beta-1 [Macaca mulatta].	22.82	631	397	22	3	585	5	593	1e-17	97.4
rs:WP_019103996	DNA topoisomerase I, partial [Chromobacterium sp. C-61].	23.21	586	377	18	84	630	49	600	1e-17	97.4
rs:WP_012968444	topoisomerase I [Klebsiella variicola].	23.06	607	384	19	60	633	78	634	1e-17	97.4
rs:XP_002181586	predicted protein [Phaeodactylum tricornutum CCAP 1055/1].	21.28	564	372	15	46	564	119	655	1e-17	97.8
rs:WP_005117044	topoisomerase I [Shigella flexneri].	23.96	601	377	24	73	633	74	634	1e-17	97.4
rs:WP_027906767	DNA topoisomerase I [Pseudomonas taiwanensis].	23.35	591	384	18	74	633	86	638	1e-17	97.4
rs:WP_037550502	DNA topoisomerase I [Spirochaeta sp. JC230].	24.48	629	368	23	3	577	6	581	1e-17	97.4
rs:WP_012850362	DNA topoisomerase I [Edwardsiella tarda].	21.78	629	417	16	38	631	2	590	2e-17	97.1
tr:A0A0B0HLX4_9BACI	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:KHF29597.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KHF29597.1};	34.73	167	104	4	1	163	1	166	2e-17	92.0
rs:WP_002668452	DNA topoisomerase I [Treponema denticola].	24.73	546	335	22	163	675	135	637	2e-17	97.1
rs:WP_009821529	DNA topoisomerase I [Sphingomonas sp. SKA58].	21.99	682	411	24	1	629	1	614	2e-17	97.4
rs:WP_007878636	DNA topoisomerase I subunit omega [Ochrobactrum sp. CDB2].	23.33	690	410	28	1	629	1	632	2e-17	97.4
rs:WP_037034469	DNA topoisomerase I [Rahnella sp. WP5].	23.89	653	381	24	76	673	82	673	2e-17	97.4
rs:WP_042859807	DNA topoisomerase I [Dickeya sp. NCPPB 3274].	23.16	639	403	22	76	673	84	675	2e-17	97.4
rs:WP_041978506	hypothetical protein [Pyrinomonas methylaliphatogenes].	25.37	611	363	22	79	631	57	632	2e-17	97.4
rs:WP_019365904	topoisomerase I [Pseudomonas luteola].	23.33	600	373	18	74	633	86	638	2e-17	97.4
tr:B9G4E5_ORYSJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.53	408	270	12	191	586	72	449	2e-17	97.4
rs:WP_018274720	topoisomerase I [Teredinibacter turnerae].	24.09	606	374	22	65	629	80	640	2e-17	97.4
rs:WP_038885822	DNA topoisomerase I [Vibrio rotiferianus].	25.00	516	293	16	163	633	174	640	2e-17	97.4
rs:WP_041907184	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.56	566	369	20	105	641	82	618	2e-17	97.1
rs:WP_037349343	DNA topoisomerase I [Selenomonas artemidis].	22.34	667	427	19	3	636	27	635	2e-17	97.4
rs:WP_045893060	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	2e-17	97.4
rs:WP_002682495	DNA topoisomerase I [Treponema denticola].	24.73	546	335	22	163	675	157	659	2e-17	97.1
rs:WP_018195577	hypothetical protein [Candidatus Fervidibacter sacchari].	23.34	707	375	30	2	616	32	663	2e-17	97.4
rs:WP_032807188	DNA topoisomerase I [Oenococcus oeni].	23.58	581	372	21	83	630	66	607	2e-17	97.1
rs:WP_040012981	DNA topoisomerase I, partial [Erysipelotrichaceae bacterium 3_1_53].	24.54	538	332	17	3	520	4	487	2e-17	97.4
rs:WP_042462364	DNA topoisomerase I [Rhodovulum sulfidophilum].	25.96	416	247	14	1	392	1	379	2e-17	97.4
rs:WP_046098886	DNA topoisomerase I [Avibacterium paragallinarum].	25.20	492	276	18	187	633	196	640	2e-17	97.4
rs:WP_034025524	DNA topoisomerase I [Pseudomonas aeruginosa].	22.41	598	381	18	74	633	85	637	2e-17	97.4
rs:WP_029889569	hypothetical protein, partial [Polycyclovorans algicola].	24.28	486	303	14	85	533	62	519	2e-17	97.4
rs:WP_008595679	DNA topoisomerase I [Nitratireductor pacificus].	23.54	701	397	31	1	630	1	633	2e-17	97.4
rs:WP_045088522	DNA topoisomerase I [Defluviitoga tunisiensis].	25.09	578	347	20	76	616	61	589	2e-17	97.4
rs:WP_046352421	DNA topoisomerase I [Janthinobacterium sp. B9-8].	24.03	595	384	21	74	630	51	615	2e-17	97.4
rs:WP_035300573	DNA topoisomerase III, partial [Clostridium sp. ATCC BAA-442].	32.26	217	132	6	474	683	3	211	2e-17	93.2
rs:XP_007451079	PREDICTED: DNA topoisomerase 3-beta-1 [Lipotes vexillifer].	23.49	630	394	23	3	585	5	593	2e-17	97.4
rs:WP_041145185	DNA topoisomerase I [Raoultella ornithinolytica].	23.12	597	387	19	73	633	74	634	2e-17	97.4
rs:WP_016324077	DNA topoisomerase I [Oscillibacter sp. 1-3].	22.50	631	394	23	90	673	68	650	2e-17	97.4
rs:WP_041890423	DNA topoisomerase I [candidate division SR1 bacterium MGEHA].	23.64	626	382	20	3	603	5	559	2e-17	97.4
rs:WP_039968868	DNA topoisomerase I [Selenomonas artemidis].	22.34	667	427	19	3	636	27	635	2e-17	97.4
tr:J9H515_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EJX08960.1};	23.42	632	387	22	3	613	6	561	2e-17	97.4
tr:A0A069DDT9_9BACL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.20	566	367	21	103	636	80	615	2e-17	97.1
rs:WP_003446618	MULTISPECIES: topoisomerase I [Pseudomonas].	23.21	474	308	12	186	633	196	639	2e-17	97.4
rs:XP_004592097	PREDICTED: DNA topoisomerase 3-beta-1 [Ochotona princeps].	22.19	631	401	21	3	585	5	593	2e-17	97.4
rs:WP_034156438	DNA topoisomerase I [Pseudomonas fluorescens].	24.11	477	300	15	186	633	196	639	2e-17	97.4
rs:WP_044828820	DNA topoisomerase I [Thalassospira sp. HJ].	22.87	704	415	27	1	639	1	641	2e-17	97.4
rs:WP_009658146	DNA topoisomerase I [Selenomonas sp. FOBRC9].	22.34	667	427	19	3	636	27	635	2e-17	97.1
rs:WP_044862322	DNA topoisomerase I, partial [Escherichia coli].	23.79	601	378	24	73	633	74	634	2e-17	97.1
rs:WP_041816684	DNA topoisomerase III, partial [Bacillus megaterium].	29.09	220	147	5	358	573	1	215	2e-17	94.4
rs:WP_024259893	DNA topoisomerase I [Shigella flexneri].	23.79	601	378	24	73	633	74	634	2e-17	97.4
rs:WP_001354108	topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	2e-17	97.4
rs:WP_036860537	DNA topoisomerase I [Porticoccus hydrocarbonoclasticus].	23.91	598	363	23	74	629	90	637	2e-17	97.4
rs:WP_034687887	DNA topoisomerase I [Enterococcus mundtii].	26.00	573	345	25	103	635	81	614	2e-17	97.1
rs:WP_021839657	DNA topoisomerase [Alistipes sp. CAG:514].	25.35	564	315	22	3	532	5	496	2e-17	97.4
rs:WP_045819603	DNA topoisomerase I [Teredinibacter sp. 1162T.S.0a.05].	24.37	599	342	22	83	629	101	640	2e-17	97.4
rs:WP_021373390	DNA topoisomerase I [Peptoclostridium difficile].	24.93	718	414	31	3	675	5	642	2e-17	97.1
rs:WP_038994330	DNA topoisomerase I [Pseudomonas putida].	24.48	482	290	15	187	633	197	639	2e-17	97.4
rs:WP_047172476	DNA topoisomerase I [Staphylococcus xylosus].	23.64	550	370	19	103	629	80	602	2e-17	97.1
rs:WP_006828261	DNA topoisomerase I [Planococcus antarcticus].	23.31	562	361	21	103	630	80	605	2e-17	97.1
rs:WP_012421655	MULTISPECIES: DNA topoisomerase 1 [Shigella].	23.63	601	379	23	73	633	74	634	2e-17	97.4
rs:WP_001353238	MULTISPECIES: topoisomerase I [Escherichia].	23.79	601	378	24	73	633	74	634	2e-17	97.4
rs:WP_032206808	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	2e-17	97.4
rs:WP_035396956	DNA topoisomerase I [Bacillus sp. JCM 19047].	24.52	571	368	19	90	629	67	605	2e-17	97.1
rs:WP_038911200	DNA topoisomerase I [Dickeya dadantii].	23.38	650	392	22	75	673	82	676	2e-17	97.4
rs:WP_009438447	DNA topoisomerase I [Selenomonas sp. oral taxon 137].	22.34	667	427	19	3	636	27	635	2e-17	97.1
rs:WP_004656891	topoisomerase I [Pseudomonas savastanoi].	23.65	592	381	20	74	633	87	639	2e-17	97.4
rs:WP_038123375	DNA topoisomerase I [Veillonella sp. ICM51a].	23.43	572	360	20	95	629	135	665	2e-17	97.1
rs:WP_027705141	DNA topoisomerase I [Zymobacter palmae].	24.38	484	289	15	186	633	201	643	2e-17	97.4
rs:WP_023316755	DNA topoisomerase 1 [Klebsiella pneumoniae].	22.61	606	388	17	60	633	78	634	2e-17	97.4
rs:WP_018748115	DNA topoisomerase I [Chitiniphilus shinanonensis].	24.07	669	408	21	3	630	5	614	2e-17	97.1
rs:WP_012283267	DNA topoisomerase I [Heliobacterium modesticaldum].	21.72	548	382	16	90	616	68	589	2e-17	97.1
tr:B9IVC2_BACCQ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.43	508	334	18	157	635	33	514	2e-17	96.7
rs:WP_038889185	DNA topoisomerase I [Vibrio campbellii].	23.59	602	364	18	77	633	90	640	2e-17	97.4
rs:WP_016775493	MULTISPECIES: topoisomerase I [Pseudomonas].	23.48	592	382	20	74	633	87	639	2e-17	97.4
rs:WP_015827822	DNA topoisomerase I [Hirschia baltica].	23.24	697	398	29	1	629	1	628	2e-17	97.4
rs:WP_010447216	topoisomerase I [Vibrio rotiferianus].	24.61	516	295	16	163	633	174	640	2e-17	97.4
rs:XP_002424239	DNA topoisomerase 3-beta, putative [Pediculus humanus corporis].	22.02	672	454	19	1	630	3	646	2e-17	97.4
rs:WP_026976557	DNA topoisomerase I [Flavobacterium tegetincola].	24.86	531	329	18	3	521	5	477	2e-17	97.4
rs:WP_025335382	DNA topoisomerase I [Paenibacillus sabinae].	23.56	590	374	23	88	636	62	615	2e-17	97.1
rs:WP_015218159	DNA topoisomerase I [Cyanobacterium aponinum].	24.43	618	355	20	3	564	4	565	2e-17	97.4
rs:WP_035052659	DNA topoisomerase I [Carnobacterium pleistocenium].	23.46	584	372	20	90	635	68	614	2e-17	97.1
rs:XP_007536504	PREDICTED: DNA topoisomerase 3-beta-1 [Erinaceus europaeus].	22.91	633	394	23	3	585	5	593	2e-17	97.4
rs:WP_017707273	hypothetical protein, partial [Pseudomonas syringae].	29.70	202	127	5	1	195	1	194	2e-17	92.0
rs:WP_035229648	DNA topoisomerase I [Alcanivorax sp. 19-m-6].	23.20	625	368	24	65	631	79	649	2e-17	97.4
rs:WP_024894350	DNA topoisomerase I [Acidithiobacillus thiooxidans].	23.47	588	366	23	89	629	67	617	2e-17	97.4
rs:WP_005696133	topoisomerase I [Haemophilus parainfluenzae].	23.62	597	381	19	73	633	83	640	2e-17	97.4
rs:WP_027700506	DNA topoisomerase I [Xylella fastidiosa].	24.08	573	347	20	3	538	5	526	2e-17	97.4
rs:WP_016391296	DNA topoisomerase I subunit omega [Pseudomonas plecoglossicida].	24.37	476	300	14	186	633	196	639	2e-17	97.4
tr:H9EST7_MACMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.82	631	397	22	3	585	5	593	2e-17	97.4
rs:WP_015407025	DNA topoisomerase I [Dehalococcoides mccartyi].	24.59	675	389	26	2	624	4	610	2e-17	97.1
rs:WP_029237111	DNA topoisomerase I [Streptococcus sobrinus].	22.76	580	374	20	83	629	87	625	2e-17	97.1
rs:WP_025700243	DNA topoisomerase I [Paenibacillus durus].	22.91	585	384	21	88	636	62	615	2e-17	97.1
rs:WP_034167620	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	2e-17	97.4
rs:WP_009603463	topoisomerase I [Vibrio caribbeanicus].	24.81	516	294	19	163	633	173	639	2e-17	97.4
rs:WP_023345728	DNA topoisomerase I [Firmicutes bacterium ASF500].	22.48	645	428	19	70	680	52	658	2e-17	97.1
rs:WP_002796370	DNA topoisomerase I [Microcystis aeruginosa].	25.53	611	349	22	3	560	4	561	2e-17	97.4
rs:WP_007205640	DNA topoisomerase I [Loktanella vestfoldensis].	21.53	692	410	22	1	629	1	622	2e-17	97.4
sp:TOP1_XYLFT	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.08	573	347	20	3	538	5	526	2e-17	97.1
rs:WP_045359707	DNA topoisomerase I [Microcystis aeruginosa].	25.20	611	351	23	3	560	4	561	2e-17	97.4
rs:XP_001785468	predicted protein [Physcomitrella patens].	22.72	625	400	24	3	586	6	588	2e-17	97.4
rs:WP_032853999	DNA topoisomerase I [Pasteurella multocida].	25.31	478	289	17	187	631	196	638	2e-17	97.4
rs:WP_035401765	DNA topoisomerase I, partial [Chlorobium sp. GBChlB].	24.88	607	350	25	83	630	63	622	2e-17	97.1
rs:WP_010965091	DNA topoisomerase I [Clostridium acetobutylicum].	24.59	545	344	17	103	616	80	588	2e-17	97.1
rs:XP_011738033	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Macaca nemestrina].	22.82	631	397	22	3	585	5	593	2e-17	97.4
rs:WP_032261103	DNA topoisomerase 1 [Escherichia coli].	24.38	603	372	25	73	633	74	634	2e-17	97.4
rs:WP_041477349	DNA topoisomerase I [Pseudomonas sp. PTA1].	23.48	592	382	20	74	633	87	639	2e-17	97.4
rs:WP_036213490	DNA topoisomerase I [Lysobacter arseniciresistens].	24.09	469	301	15	103	538	80	526	2e-17	97.1
rs:WP_003302513	DNA topoisomerase I subunit omega, partial [Pseudomonas stutzeri].	23.64	478	299	12	187	633	153	595	2e-17	97.1
tr:F6QNQ6_MACMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.82	631	397	22	3	585	5	593	2e-17	97.1
tr:A0A0D6A520_9LACO	SubName: Full=Truncated topoisomerase {ECO:0000313|EMBL:BAQ57555.1};	25.75	268	177	4	261	516	18	275	2e-17	93.6
tr:X1EDM6_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_C01304 {ECO:0000313|EMBL:GAH30712.1}; Flags: Fragment;	26.08	441	290	18	1	420	1	426	2e-17	95.9
rs:WP_006638185	DNA topoisomerase I [Bacillus sonorensis].	23.89	561	368	21	105	635	82	613	2e-17	97.1
rs:WP_047256160	DNA topoisomerase I [Moellerella wisconsensis].	23.44	529	318	15	187	673	189	672	2e-17	97.1
rs:WP_038863258	DNA topoisomerase I [Vibrio campbellii].	23.46	601	366	18	77	633	90	640	2e-17	97.4
rs:WP_005087983	topoisomerase I [Shigella flexneri].	23.79	601	378	24	73	633	74	634	2e-17	97.1
rs:WP_011309190	DNA topoisomerase I [Dehalococcoides mccartyi].	24.59	675	389	26	2	624	4	610	2e-17	97.1
rs:WP_009842753	topoisomerase I [Vibrio sp. AND4].	23.79	597	369	17	77	633	90	640	2e-17	97.1
rs:XP_010618951	PREDICTED: DNA topoisomerase 3-beta-1 [Fukomys damarensis].	22.84	626	403	20	3	585	5	593	2e-17	97.1
rs:WP_036989641	DNA topoisomerase I [Pseudomonas bauzanensis].	22.54	590	392	16	74	633	84	638	2e-17	97.1
rs:WP_006312670	MULTISPECIES: DNA topoisomerase I [Agrobacterium].	22.84	705	400	28	1	630	1	636	2e-17	97.4
rs:WP_038229912	DNA topoisomerase I [Xylella fastidiosa].	24.08	573	347	20	3	538	5	526	2e-17	97.1
rs:WP_033977639	DNA topoisomerase 1 [Pseudomonas aeruginosa].	22.54	599	379	19	74	633	85	637	2e-17	97.1
rs:WP_034897251	DNA topoisomerase I [Erwinia typographi].	22.77	593	387	17	75	633	79	634	2e-17	97.1
rs:WP_035428988	DNA topoisomerase I [Bacillus sp. UNC322MFChir4.1].	24.32	584	379	24	105	655	82	635	2e-17	97.1
rs:WP_040596886	DNA topoisomerase I [Parvimonas micra].	24.51	669	396	27	3	630	5	605	2e-17	97.1
tr:A0A087QIU6_APTFO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.09	563	363	18	36	564	26	552	2e-17	97.1
rs:WP_004179471	topoisomerase I [Klebsiella pneumoniae].	22.61	606	388	17	60	633	78	634	2e-17	97.1
rs:WP_037325674	DNA topoisomerase I [Anaerovibrio sp. RM50].	24.54	546	349	20	103	616	75	589	2e-17	97.1
gp:CP000446_1580	DNA topoisomerase I [Shewanella sp. MR-4]	23.86	482	292	16	187	631	214	657	2e-17	97.1
rs:WP_029200664	DNA topoisomerase I [Oribacterium sp. NK2B42].	23.28	640	404	21	3	616	5	583	2e-17	96.7
rs:WP_010797697	DNA topoisomerase 1 [Pseudomonas sp. HPB0071].	23.33	600	373	18	74	633	86	638	2e-17	97.1
rs:WP_022025442	DNA topoisomerase [Clostridium sp. CAG:75].	23.78	555	362	16	90	616	67	588	2e-17	97.1
rs:WP_010645814	topoisomerase I [Vibrio campbellii].	23.59	602	364	18	77	633	90	640	2e-17	97.1
rs:WP_037021839	DNA topoisomerase I [Pseudomonas sp. 20_BN].	23.06	477	303	13	187	633	193	635	2e-17	97.1
rs:WP_040469686	DNA topoisomerase I [Lactobacillus ingluviei].	24.69	563	350	20	88	616	82	604	2e-17	97.1
rs:WP_022360248	DNA topoisomerase [Clostridium sp. CAG:43].	25.57	571	343	20	90	616	67	599	2e-17	97.1
rs:WP_001698309	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	2e-17	97.1
rs:WP_023478680	DNA topoisomerase I [Enterobacter cloacae].	23.84	604	374	22	73	633	74	634	2e-17	97.1
tr:U1MJ04_9EURY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.03	469	296	15	83	521	78	511	2e-17	97.1
rs:WP_043765344	DNA topoisomerase I [Roseivivax isoporae].	21.36	721	411	24	1	630	1	656	2e-17	97.1
tr:G6BMM8_PEPDI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.14	720	410	33	3	675	11	648	2e-17	97.1
rs:XP_007196358	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Balaenoptera acutorostrata scammoni].	23.49	630	394	23	3	585	5	593	2e-17	97.1
rs:WP_008928140	topoisomerase I [Alcanivorax hongdengensis].	22.13	601	400	18	65	629	79	647	2e-17	97.1
rs:WP_022695662	DNA topoisomerase I [Ponticaulis koreensis].	23.54	684	407	29	1	629	1	623	2e-17	97.1
rs:WP_036956550	DNA topoisomerase I [Providencia alcalifaciens].	23.23	594	383	17	74	633	88	642	2e-17	97.1
rs:WP_005786156	topoisomerase I [Pseudomonas synxantha].	23.89	473	304	13	187	633	197	639	2e-17	97.1
rs:WP_041409019	DNA topoisomerase I [Shewanella sp. MR-4].	23.86	482	292	16	187	631	198	641	2e-17	97.1
rs:WP_022724748	DNA topoisomerase I [alpha proteobacterium SCGC AAA536-K22].	25.18	683	399	28	1	629	1	625	2e-17	97.1
rs:WP_031552313	DNA topoisomerase I [Gemella sanguinis].	24.13	572	338	21	103	629	81	601	2e-17	96.7
rs:WP_039228825	MULTISPECIES: DNA topoisomerase I [Clostridium].	24.34	645	396	21	2	616	4	586	2e-17	96.7
rs:WP_040266076	DNA topoisomerase I [Serratia symbiotica].	23.49	647	395	24	74	673	80	673	2e-17	97.1
rs:WP_039549548	DNA topoisomerase I [Pectobacterium carotovorum].	24.25	598	372	21	74	633	81	635	2e-17	97.1
rs:WP_031447743	DNA topoisomerase I [Caulobacteraceae bacterium PMMR1].	22.66	609	373	18	1	565	1	555	2e-17	97.1
rs:WP_014113782	DNA topoisomerase I [Bacillus subtilis].	23.89	565	374	19	105	641	82	618	2e-17	96.7
rs:WP_028632472	DNA topoisomerase I [Pseudomonas parafulva].	24.42	475	299	14	187	633	197	639	2e-17	97.1
rs:XP_011842736	PREDICTED: DNA topoisomerase 3-beta-1 [Mandrillus leucophaeus].	22.82	631	397	22	3	585	5	593	2e-17	97.1
rs:WP_012961160	DNA topoisomerase III [Bacillus pseudofirmus].	27.18	287	193	7	1	272	1	286	2e-17	93.6
rs:WP_003297053	DNA topoisomerase I subunit omega [Pseudomonas stutzeri].	23.43	478	300	12	187	633	194	636	2e-17	97.1
rs:WP_000772478	DNA topoisomerase I [Escherichia coli].	23.12	493	309	14	168	631	138	589	2e-17	96.7
rs:WP_025153127	DNA topoisomerase I [Morganella morganii].	23.77	530	314	18	187	673	188	670	2e-17	97.1
rs:WP_032877218	DNA topoisomerase I [Pseudomonas sp. BRG-100].	23.89	473	304	13	187	633	197	639	2e-17	97.1
rs:WP_001669681	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	2e-17	97.1
rs:WP_021651815	MULTISPECIES: DNA topoisomerase I [Clostridiales].	22.91	563	356	20	90	616	67	587	2e-17	96.7
rs:WP_001433303	topoisomerase I [Escherichia coli].	23.58	598	383	23	73	633	74	634	2e-17	97.1
rs:WP_003705339	DNA topoisomerase I [Neisseria gonorrhoeae].	22.83	727	452	26	3	679	5	672	2e-17	97.1
tr:A0A0B8PX27_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAM69257.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAM69257.1};	32.37	207	127	6	2	199	3	205	2e-17	92.4
rs:WP_009839581	topoisomerase I [Pseudoalteromonas tunicata].	24.04	628	381	24	52	631	63	642	2e-17	97.1
rs:WP_032881893	DNA topoisomerase I [Fusobacterium hwasookii].	24.38	603	375	19	2	580	9	554	2e-17	97.1
rs:WP_009636003	topoisomerase I [Serratia sp. M24T3].	23.24	654	384	25	76	673	82	673	2e-17	97.1
rs:WP_046481020	DNA topoisomerase I [Citrobacter amalonaticus].	23.37	599	383	19	73	633	74	634	2e-17	97.1
rs:WP_021387786	DNA topoisomerase I [Peptoclostridium difficile].	25.14	720	410	33	3	675	5	642	2e-17	96.7
rs:WP_035767149	DNA topoisomerase I [Butyrivibrio sp. NC2002].	24.78	557	356	21	90	616	70	593	2e-17	96.7
rs:WP_016475614	DNA topoisomerase I [Veillonella sp. HPA0037].	24.31	576	350	22	95	629	135	665	2e-17	97.1
rs:WP_045508058	DNA topoisomerase I [Kosakonia oryzae].	23.51	604	376	22	73	633	74	634	2e-17	97.1
rs:WP_043016148	DNA topoisomerase I [Citrobacter freundii].	23.45	597	385	22	73	633	74	634	2e-17	97.1
rs:WP_037281968	DNA topoisomerase I [Ruminococcus flavefaciens].	24.29	560	356	18	90	616	72	596	2e-17	96.7
tr:A0A0D1WHV3_9EURO	SubName: Full=Strain CBS 40295 unplaced genomic scaffold supercont1.6, whole genome shotgun sequence {ECO:0000313|EMBL:KIV88395.1};	23.86	658	365	27	3	584	7	604	2e-17	96.7
rs:WP_038369385	DNA topoisomerase I [Pseudomonas chlororaphis].	23.48	592	382	20	74	633	87	639	2e-17	97.1
rs:WP_035636833	DNA topoisomerase I [Flavobacterium sp. EM1308].	25.14	529	330	18	3	521	5	477	2e-17	97.1
rs:WP_037399137	MULTISPECIES: DNA topoisomerase I [Serratia].	24.34	608	359	22	74	633	80	634	2e-17	97.1
rs:WP_027347737	DNA topoisomerase I [Helcococcus sueciensis].	24.73	655	382	26	3	618	5	587	2e-17	96.7
rs:WP_009003194	DNA topoisomerase I [Clostridium sp. D5].	24.28	556	359	18	90	616	67	589	2e-17	96.7
tr:D2ADR0_SHIF2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.79	601	378	24	73	633	88	648	2e-17	97.1
rs:WP_025746457	DNA topoisomerase I [Caldicoprobacter oshimai].	23.58	564	357	19	90	616	67	593	2e-17	96.7
rs:WP_038658773	DNA topoisomerase I [Cedecea neteri].	23.16	639	403	22	76	673	84	675	2e-17	97.1
rs:WP_030092621	DNA topoisomerase I [Sphingomonas sp. DC-6].	22.65	724	458	28	1	675	1	671	2e-17	97.1
rs:XP_006177120	PREDICTED: DNA topoisomerase 3-beta-1 [Camelus ferus].	22.43	633	397	23	3	585	5	593	2e-17	97.1
rs:WP_016495870	topoisomerase I [Enterobacter sp. R4-368].	23.51	604	376	22	73	633	74	634	2e-17	97.1
rs:WP_022016854	DNA topoisomerase [Bacteroides sp. CAG:545].	25.70	502	299	18	3	480	5	456	2e-17	97.1
rs:WP_014103479	DNA topoisomerase I [Micavibrio aeruginosavorus].	22.97	688	409	28	3	629	6	633	2e-17	97.1
rs:WP_008828828	MULTISPECIES: DNA topoisomerase I [Sphingomonadaceae].	22.16	677	418	22	1	629	1	616	2e-17	97.1
rs:WP_038522534	DNA topoisomerase I [Lactobacillus sp. wkB8].	24.51	559	353	21	103	629	89	610	2e-17	96.7
rs:WP_027606776	DNA topoisomerase I [Pseudomonas sp. LAMO17WK12:I2].	22.18	586	379	13	77	638	62	594	2e-17	96.7
rs:WP_024562448	MULTISPECIES: DNA topoisomerase I [Cronobacter].	23.88	603	375	17	73	633	74	634	2e-17	97.1
rs:WP_001553967	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	2e-17	97.1
rs:WP_020012348	MULTISPECIES: DNA topoisomerase I [Agrobacterium].	23.35	668	390	27	38	630	16	636	2e-17	97.1
rs:WP_029488353	DNA topoisomerase I [Epulopiscium sp. 'N.t. morphotype B'].	25.49	557	345	20	90	616	67	583	2e-17	96.7
rs:WP_025015133	DNA topoisomerase I [Lactobacillus kitasatonis].	24.56	566	358	22	103	635	93	622	2e-17	96.7
tr:K1S3X1_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC48415.1};	37.91	153	89	2	155	307	15	161	2e-17	92.0
rs:WP_026605122	DNA topoisomerase [Methylobacterium sp. 285MFTsu5.1].	21.88	640	386	25	44	602	27	633	2e-17	97.1
rs:WP_019601517	topoisomerase I [Teredinibacter turnerae].	23.47	605	379	20	65	629	80	640	2e-17	97.1
rs:WP_040038412	DNA topoisomerase I [Escherichia coli].	23.58	598	383	23	73	633	74	634	2e-17	97.1
rs:WP_025759091	DNA topoisomerase I [Shigella flexneri].	23.79	601	378	24	73	633	74	634	2e-17	97.1
rs:XP_006021588	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Alligator sinensis].	24.05	395	251	10	188	564	115	478	2e-17	96.7
rs:WP_023639723	topoisomerase I [Dickeya zeae].	22.71	643	405	21	75	673	87	681	2e-17	97.1
rs:WP_022623213	topoisomerase I [Pantoea ananatis].	23.28	597	379	21	75	633	79	634	2e-17	97.1
rs:WP_013317897	topoisomerase I [Dickeya dadantii].	23.38	650	392	22	75	673	81	675	2e-17	97.1
rs:WP_012884779	topoisomerase I [Dickeya dadantii].	22.86	643	404	21	75	673	87	681	2e-17	97.1
rs:WP_034979206	DNA topoisomerase I [Lactobacillus sp. wkB10].	24.29	560	353	20	103	629	89	610	2e-17	96.7
rs:WP_044825956	DNA topoisomerase I [Clostridium aceticum].	25.71	564	341	21	103	629	80	602	2e-17	96.7
rs:WP_003686257	DNA topoisomerase I [Neisseria flavescens].	22.97	727	451	26	3	679	5	672	2e-17	96.7
rs:XP_005391750	PREDICTED: DNA topoisomerase 3-beta-1 isoform X5 [Chinchilla lanigera].	22.66	631	396	21	3	585	5	591	2e-17	97.1
tr:J9GHA6_9ZZZZ	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EJW98799.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EJW98799.1};	37.43	171	96	5	463	627	31	196	2e-17	93.6
rs:XP_007091145	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Panthera tigris altaica].	23.05	629	398	22	3	585	5	593	2e-17	97.1
rs:WP_027326478	DNA topoisomerase I [Bacteroides pyogenes].	24.89	470	297	14	77	526	54	487	2e-17	96.7
rs:WP_019790039	DNA topoisomerase I [Streptococcus sobrinus].	23.37	582	368	22	83	629	87	625	2e-17	96.7
rs:WP_046874733	DNA topoisomerase I [Vibrio alginolyticus].	23.30	588	389	16	75	633	86	640	2e-17	97.1
rs:WP_035903139	DNA topoisomerase I [Fusobacterium necrophorum].	26.92	598	325	24	3	561	6	530	2e-17	96.7
rs:WP_008902384	DNA topoisomerase I [Peptoniphilus duerdenii].	23.24	710	428	25	3	671	5	638	2e-17	96.7
rs:WP_004569061	DNA topoisomerase I [Polaribacter irgensii].	25.56	532	324	18	3	521	5	477	2e-17	97.1
rs:WP_031545533	DNA topoisomerase I [Lachnospiraceae bacterium AC2014].	23.38	633	392	22	83	673	60	641	2e-17	96.7
tr:V6TB61_GIAIN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESU36111.1};	24.45	642	411	29	1	589	1	621	2e-17	97.1
rs:WP_008278471	DNA topoisomerase I [Cyanothece sp. CCY0110].	25.50	498	290	18	84	544	61	514	2e-17	96.7
rs:XP_011286220	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Felis catus].	23.05	629	398	22	3	585	5	593	2e-17	97.1
rs:WP_003385908	DNA topoisomerase I [Brevibacillus borstelensis].	23.09	563	374	21	103	635	80	613	2e-17	96.7
rs:WP_041169266	DNA topoisomerase I, partial [Helicobacter pylori].	24.69	486	328	14	75	536	46	517	2e-17	95.9
rs:WP_005032880	topoisomerase I [Shigella dysenteriae].	23.07	646	406	26	73	673	74	673	2e-17	97.1
rs:WP_025566026	DNA topoisomerase I [Psychromonas sp. SP041].	24.50	596	368	21	77	633	91	643	2e-17	97.1
rs:WP_026466076	DNA topoisomerase I [Aerococcus urinaeequi].	23.68	570	368	20	90	629	68	600	2e-17	96.7
rs:WP_013978147	DNA topoisomerase I [Clostridium sp. SY8519].	24.25	565	347	21	90	616	67	588	2e-17	96.7
rs:WP_046660009	DNA topoisomerase I, partial [Escherichia coli].	23.79	601	378	24	73	633	74	634	2e-17	96.7
rs:WP_020451381	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.06	561	367	21	105	635	82	613	2e-17	96.7
rs:WP_019624066	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	23.05	564	354	18	3	534	5	520	2e-17	97.1
tr:L8HVJ0_9CETA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.58	629	401	22	3	585	5	593	2e-17	96.7
rs:WP_014820598	topoisomerase I [Pseudomonas stutzeri].	23.43	478	300	12	187	633	194	636	2e-17	97.1
rs:WP_019845082	topoisomerase I [Dickeya zeae].	22.71	643	405	21	75	673	87	681	2e-17	97.1
rs:WP_042644165	DNA topoisomerase I [Mesorhizobium sp. ORS3359].	23.11	701	400	28	1	630	1	633	2e-17	97.1
rs:WP_045928058	DNA topoisomerase I [Lactobacillus kullabergensis].	24.29	560	353	20	103	629	89	610	2e-17	96.7
rs:WP_008837879	DNA topoisomerase I [Mesorhizobium alhagi].	23.18	699	402	28	1	630	1	633	2e-17	97.1
rs:WP_044697417	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	2e-17	97.1
rs:WP_001298801	topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	2e-17	97.1
rs:WP_003226594	topoisomerase I [Pseudomonas fluorescens].	24.16	476	299	15	187	633	197	639	2e-17	97.1
rs:WP_028611049	DNA topoisomerase I [Paenibacillus harenae].	24.54	648	397	29	88	687	62	665	2e-17	96.7
rs:WP_036479525	DNA topoisomerase I [Myxosarcina sp. GI1].	25.22	575	333	20	3	530	4	528	2e-17	97.1
rs:WP_028669069	DNA topoisomerase I [Runella zeae].	25.85	468	293	13	77	526	54	485	2e-17	96.7
gp:CP002165_604	DNA topoisomerase I [Xylella fastidiosa subsp. fastidiosa GB514]	24.08	573	347	20	3	538	5	526	2e-17	96.7
rs:WP_033095677	DNA topoisomerase I [Colwellia psychrerythraea].	22.85	652	425	21	65	680	75	684	2e-17	97.1
rs:WP_001437935	topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	2e-17	96.7
rs:WP_014451788	DNA topoisomerase I [Fervidobacterium pennivorans].	23.77	648	391	22	2	618	37	612	2e-17	96.7
rs:XP_003240406	PREDICTED: DNA topoisomerase 3-beta-1 [Acyrthosiphon pisum].	24.25	499	318	15	188	655	210	679	2e-17	96.7
rs:WP_047235810	DNA topoisomerase I [Streptococcus pyogenes].	23.21	560	356	18	103	629	103	621	2e-17	96.7
rs:WP_022050564	DNA topoisomerase [Ruminococcus sp. CAG:254].	24.59	671	410	29	55	675	28	652	2e-17	96.7
rs:WP_022684221	DNA topoisomerase I [Sphingobium sp. YL23].	20.80	721	471	23	1	679	1	663	2e-17	96.7
rs:WP_042843673	DNA topoisomerase I [Providencia rettgeri].	23.72	506	309	15	57	539	80	531	2e-17	96.7
rs:WP_037624562	DNA topoisomerase I [Streptococcus uberis].	22.47	583	372	19	83	629	84	622	2e-17	96.7
rs:WP_008437341	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	22.18	568	374	17	77	614	62	591	2e-17	96.3
rs:WP_041572324	DNA topoisomerase I, partial [Xylella fastidiosa].	24.08	573	347	20	3	538	5	526	2e-17	96.7
rs:WP_003220843	DNA topoisomerase I [Bacillus subtilis].	24.38	566	370	20	105	641	82	618	3e-17	96.7
rs:WP_012707655	DNA topoisomerase I [Sinorhizobium fredii].	23.09	693	413	28	1	630	1	636	3e-17	96.7
rs:WP_024821701	DNA topoisomerase I [Aminobacterium mobile].	26.49	604	354	24	83	636	65	628	3e-17	96.7
rs:WP_026663998	DNA topoisomerase I [Butyrivibrio sp. AE2015].	23.88	557	361	17	90	616	61	584	3e-17	96.7
rs:WP_011025719	DNA topoisomerase I [Caldanaerobacter subterraneus].	23.62	580	365	20	90	629	67	608	3e-17	96.7
rs:WP_027443042	DNA topoisomerase I [Porphyrobacter cryptus].	22.32	672	426	23	1	629	1	619	3e-17	96.7
rs:WP_027390823	DNA topoisomerase I [Chrysiogenes arsenatis].	24.15	679	391	26	3	630	6	611	3e-17	96.7
rs:WP_012185183	DNA topoisomerase [Caldivirga maquilingensis].	22.20	608	383	21	2	564	3	565	3e-17	96.3
rs:WP_031378741	DNA topoisomerase I [Bacillus amyloliquefaciens].	23.81	567	372	21	105	641	82	618	3e-17	96.7
rs:WP_000513608	DNA topoisomerase I subunit omega, partial [Shigella dysenteriae].	23.07	646	406	26	73	673	74	673	3e-17	96.7
rs:WP_046893610	DNA topoisomerase I [Morganella morganii].	23.74	535	321	16	187	680	188	676	3e-17	96.7
rs:WP_040486728	DNA topoisomerase I, partial [Idiomarina sp. A28L].	24.16	534	325	21	186	680	195	687	3e-17	96.7
tr:F9QAQ0_9PAST	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.83	596	377	19	74	633	10	564	3e-17	96.7
rs:WP_001625658	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_000513590	topoisomerase I [Salmonella enterica].	23.79	597	383	20	73	633	74	634	3e-17	96.7
rs:WP_003368142	DNA topoisomerase III, partial [Pseudomonas syringae].	28.57	203	130	5	1	196	1	195	3e-17	91.7
gp:AP012209_678	DNA topoisomerase [Candidatus Arthromitus sp. SFB-mouse-Yit]	25.32	541	338	17	103	614	50	553	3e-17	96.3
rs:WP_008793675	DNA topoisomerase I [Fusobacterium periodonticum].	25.32	620	370	22	2	589	9	567	3e-17	96.7
rs:WP_001347791	DNA topoisomerase 1 [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_013172665	DNA topoisomerase I [[Bacillus] selenitireducens].	23.04	573	375	20	90	630	67	605	3e-17	96.3
rs:WP_044654725	DNA topoisomerase I [Bacteroides acidifaciens].	24.03	620	377	22	3	596	5	556	3e-17	96.7
rs:WP_010829429	DNA topoisomerase 1 [Enterococcus faecalis].	24.87	563	350	23	103	629	81	606	3e-17	96.3
tr:V9QQE9_9PSED	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.18	568	374	17	77	614	75	604	3e-17	96.3
rs:WP_043084341	DNA topoisomerase I [Pluralibacter gergoviae].	23.08	598	379	18	74	633	80	634	3e-17	96.7
rs:WP_001663866	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_001592150	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_031943451	DNA topoisomerase [uncultured bacterium].	24.08	490	307	15	168	631	138	588	3e-17	96.3
rs:WP_010226976	MULTISPECIES: topoisomerase I [Pseudomonas].	25.00	476	295	15	187	633	197	639	3e-17	96.7
rs:WP_025077717	DNA topoisomerase I [Prevotella fusca].	24.51	608	353	22	3	578	5	538	3e-17	96.7
rs:WP_025029833	DNA topoisomerase I [Nitratireductor aquibiodomus].	21.71	700	411	27	1	630	1	633	3e-17	96.7
rs:WP_044325484	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_006101735	DNA topoisomerase I [Coleofasciculus chthonoplastes].	24.35	575	351	18	90	614	71	611	3e-17	96.7
rs:WP_024018204	DNA topoisomerase I [Sphingobium sp. C100].	21.93	725	460	28	1	680	1	664	3e-17	96.7
rs:WP_024870611	DNA topoisomerase I [Tolumonas sp. BRL6-1].	24.71	603	361	22	74	633	84	636	3e-17	96.7
rs:WP_027273071	DNA topoisomerase I [Leminorella grimontii].	23.81	651	397	24	76	680	78	675	3e-17	96.7
gp:AF099909_1	topoisomerase III [Drosophila melanogaster]	24.30	461	302	15	188	630	211	642	3e-17	96.7
rs:WP_006709699	topoisomerase I [Serratia symbiotica].	22.97	640	409	22	74	673	80	675	3e-17	96.7
rs:WP_017372301	topoisomerase I [Enterobacteriaceae bacterium LSJC7].	22.82	609	374	20	73	633	77	637	3e-17	96.7
rs:WP_032823878	DNA topoisomerase I [Oenococcus oeni].	23.58	581	372	21	83	630	66	607	3e-17	96.3
tr:A8SJ74_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.51	669	396	27	3	630	11	611	3e-17	96.3
rs:WP_007371932	topoisomerase I [Kosakonia radicincitans].	23.51	604	376	22	73	633	74	634	3e-17	96.7
rs:WP_001355506	DNA topoisomerase I subunit omega [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_015925504	DNA topoisomerase I [[Clostridium] cellulolyticum].	24.82	556	337	19	103	616	80	596	3e-17	96.3
rs:WP_013523392	MULTISPECIES: DNA topoisomerase I [Geobacillus].	24.64	556	358	19	105	630	82	606	3e-17	96.3
rs:WP_045855064	DNA topoisomerase I [Raoultella terrigena].	23.12	597	387	19	73	633	74	634	3e-17	96.7
rs:WP_001326307	topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_001437686	topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
tr:I6H4J9_SHIFL	SubName: Full=DNA topoisomerase 3 domain protein {ECO:0000313|EMBL:EIQ75691.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EIQ75691.1}; Flags: Fragment;	33.48	221	127	7	84	284	5	225	3e-17	92.4
rs:WP_019625965	DNA topoisomerase I [Thioalkalivibrio sp. ALJT].	22.40	576	354	17	3	534	5	531	3e-17	96.7
rs:WP_027974779	DNA topoisomerase I [Streptococcus porci].	23.48	575	363	22	90	630	86	617	3e-17	96.3
rs:WP_020434135	DNA topoisomerase I [Paenibacillus riograndensis].	23.71	582	383	21	88	636	62	615	3e-17	96.3
rs:WP_016239518	DNA topoisomerase 1 [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_047086937	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
tr:A0A091TD74_PHALP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.09	563	363	18	36	564	26	552	3e-17	96.7
tr:Q0HW50_SHESR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.86	482	292	16	187	631	214	657	3e-17	96.7
rs:WP_044360969	DNA topoisomerase I [Staphylococcus microti].	23.33	570	374	21	90	629	67	603	3e-17	96.3
rs:WP_033077867	DNA topoisomerase I [Thalassotalea sp. ND16A].	24.24	594	366	21	77	629	89	639	3e-17	96.7
rs:WP_023484649	DNA topoisomerase I-like protein [Paenibacillus larvae].	24.31	576	354	24	103	636	80	615	3e-17	96.3
rs:WP_001641657	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_002989768	DNA topoisomerase I [Streptococcus pyogenes].	23.39	560	355	18	103	629	103	621	3e-17	96.3
rs:WP_030125930	DNA topoisomerase I [Streptococcus pyogenes].	23.39	560	355	18	103	629	103	621	3e-17	96.3
rs:WP_046414027	DNA topoisomerase I [Ruminococcus sp. A254.MGS-254].	24.59	671	410	29	55	675	28	652	3e-17	96.3
rs:WP_032968854	DNA topoisomerase I, partial [Cronobacter malonaticus].	24.38	480	295	18	187	633	5	449	3e-17	96.3
rs:WP_004744344	topoisomerase I [Vibrio tubiashii].	24.07	615	371	19	57	633	83	639	3e-17	96.7
rs:WP_002693373	DNA topoisomerase I [Treponema denticola].	24.54	546	336	22	163	675	157	659	3e-17	96.3
rs:WP_034129460	DNA topoisomerase I [Acinetobacter baumannii].	25.20	488	321	14	67	540	51	508	3e-17	96.7
rs:WP_043857492	DNA topoisomerase 1 [Bacillus subtilis].	23.59	568	374	20	105	642	82	619	3e-17	96.3
rs:WP_003915304	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_044808717	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_039384579	DNA topoisomerase I [Pantoea sp. PSNIH1].	23.41	534	325	17	187	680	190	679	3e-17	96.7
rs:WP_001574321	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_001481542	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_001704495	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_039578790	DNA topoisomerase I [Pseudomonas parafulva].	23.52	591	383	19	74	633	86	638	3e-17	96.7
rs:WP_002554104	topoisomerase I [Pseudomonas savastanoi].	23.65	592	381	20	74	633	87	639	3e-17	96.7
rs:XP_004400575	PREDICTED: DNA topoisomerase 3-beta-1 [Odobenus rosmarus divergens].	22.50	631	399	22	3	585	5	593	3e-17	96.7
rs:WP_029276016	DNA topoisomerase I [Carnobacterium jeotgali].	23.80	584	370	23	90	635	68	614	3e-17	96.3
rs:XP_006269380	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Alligator mississippiensis].	24.05	395	251	10	188	564	115	478	3e-17	96.7
tr:D6HW37_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.79	601	378	24	73	633	76	636	3e-17	96.7
rs:WP_001695925	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_041417181	DNA topoisomerase I [Shewanella sp. MR-7].	23.86	482	292	16	187	631	198	641	3e-17	96.7
rs:WP_023379575	DNA topoisomerase I subunit omega [Pseudomonas sp. VLB120].	23.18	591	385	18	74	633	86	638	3e-17	96.7
rs:WP_020949217	DNA topoisomerase I [Paracoccus aminophilus].	22.45	695	435	26	1	647	1	639	3e-17	96.7
rs:WP_034126645	DNA topoisomerase I [Pseudomonas fluorescens].	24.05	474	302	14	187	633	197	639	3e-17	96.7
rs:WP_002901763	MULTISPECIES: DNA topoisomerase I [Klebsiella].	22.61	606	388	17	60	633	78	634	3e-17	96.7
rs:WP_001678703	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_001397166	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_013346029	topoisomerase I [Ferrimonas balearica].	22.64	592	384	16	77	633	93	645	3e-17	96.7
rs:WP_001382110	topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
tr:F4VBV2_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.79	601	378	24	73	633	88	648	3e-17	96.7
rs:WP_040205630	DNA topoisomerase III, partial [Klebsiella pneumoniae].	25.57	395	221	12	349	673	44	435	3e-17	95.1
rs:WP_024983845	DNA topoisomerase I [Brevibacillus borstelensis].	23.09	563	374	21	103	635	80	613	3e-17	96.3
rs:WP_019818246	DNA topoisomerase I [Pseudomonas sp. CFT9].	23.89	473	304	13	187	633	197	639	3e-17	96.7
rs:WP_042394310	DNA topoisomerase I [Escherichia vulneris].	24.34	604	371	23	73	633	74	634	3e-17	96.7
rs:XP_002071612	GK10076 [Drosophila willistoni].	24.89	462	298	16	188	630	211	642	3e-17	96.7
rs:WP_024556117	DNA topoisomerase I [Cronobacter pulveris].	23.24	598	385	17	73	633	75	635	3e-17	96.7
rs:WP_001342100	MULTISPECIES: topoisomerase I [Enterobacteriaceae].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_012765531	MULTISPECIES: topoisomerase I [Dickeya].	22.17	636	416	18	74	673	84	676	3e-17	96.7
rs:WP_044317786	DNA topoisomerase I [Pseudomonas amygdali].	23.65	592	381	20	74	633	87	639	3e-17	96.7
rs:WP_005744458	topoisomerase I [Pseudomonas amygdali].	23.65	592	381	20	74	633	87	639	3e-17	96.7
rs:WP_015505597	DNA topoisomerase I [Erwinia amylovora].	23.12	493	309	14	168	631	138	589	3e-17	96.3
rs:WP_036937101	DNA topoisomerase I [Proteus vulgaris].	22.26	539	312	17	187	673	190	673	3e-17	96.7
rs:WP_004970853	topoisomerase I [Shigella boydii].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_001466145	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_010940644	DNA topoisomerase I [Desulfovibrio vulgaris].	22.31	605	373	21	76	629	53	611	3e-17	96.3
rs:WP_025090185	DNA topoisomerase I [Ochrobactrum intermedium].	24.82	689	401	33	1	629	1	632	3e-17	96.7
rs:WP_002776977	DNA topoisomerase I [Microcystis aeruginosa].	25.04	611	352	22	3	560	4	561	3e-17	96.7
rs:WP_041953509	DNA topoisomerase I [Parvimonas micra].	24.33	670	396	28	3	630	5	605	3e-17	96.3
rs:WP_032434376	DNA topoisomerase I [Klebsiella pneumoniae].	22.61	606	388	17	60	633	78	634	3e-17	96.7
rs:WP_001599360	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_001372673	topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_001396571	topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_046640933	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_001703146	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_004998368	topoisomerase I [Shigella boydii].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_009201701	DNA topoisomerase I [Anaerobaculum hydrogeniformans].	23.88	578	357	24	90	629	71	603	3e-17	96.3
rs:WP_037457389	DNA topoisomerase I [Sphingobium chlorophenolicum].	21.45	676	422	22	1	629	1	614	3e-17	96.7
rs:WP_044320774	DNA topoisomerase I [Pseudomonas amygdali].	23.65	592	381	20	74	633	87	639	3e-17	96.7
rs:XP_003807785	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Pan paniscus].	22.66	631	398	22	3	585	5	593	3e-17	96.7
rs:WP_018864622	DNA topoisomerase I [Thioalkalivibrio sp. ARh3].	23.36	565	351	19	3	534	5	520	3e-17	96.7
rs:WP_042049273	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_042362837	DNA topoisomerase I [Staphylococcus xylosus].	23.09	550	373	18	103	629	80	602	3e-17	96.3
rs:WP_005806337	MULTISPECIES: DNA topoisomerase I [Candidatus Arthromitus].	25.32	541	338	17	103	614	80	583	3e-17	96.3
rs:WP_008976266	MULTISPECIES: DNA topoisomerase I [Coprococcus].	24.19	554	362	17	90	616	67	589	3e-17	96.3
rs:WP_007440320	DNA topoisomerase, partial [Candidatus Arthromitus sp. SFB-1].	25.32	541	338	17	103	614	80	583	3e-17	96.3
rs:WP_033741827	DNA topoisomerase I [Pantoea stewartii].	22.50	600	380	18	75	633	79	634	3e-17	96.7
rs:WP_020851581	DNA topoisomerase I [Xylella fastidiosa].	24.08	573	347	20	3	538	5	526	3e-17	96.7
rs:XP_001684460	putative DNA topoisomerase III [Leishmania major strain Friedlin].	21.71	608	397	18	3	571	6	573	3e-17	96.7
rs:WP_034438725	DNA topoisomerase I [Candidatus Clostridium anorexicamassiliense].	24.86	551	347	17	97	616	74	588	3e-17	96.3
rs:WP_029052307	DNA topoisomerase I [Sporosarcina ureae].	22.62	557	378	18	100	630	77	606	3e-17	96.3
rs:WP_004239222	MULTISPECIES: DNA topoisomerase I [Morganella].	23.48	528	318	15	187	673	188	670	3e-17	96.7
rs:WP_029353009	DNA topoisomerase I [Mesorhizobium ciceri].	23.25	701	399	26	1	630	1	633	3e-17	96.7
rs:WP_011261684	DNA topoisomerase I [Aliivibrio fischeri].	24.85	507	305	17	163	633	172	638	3e-17	96.7
rs:WP_025439297	DNA topoisomerase I [Komagataeibacter xylinus].	21.80	610	383	23	3	571	4	560	3e-17	96.7
rs:WP_020321645	DNA topoisomerase I [Klebsiella pneumoniae].	22.61	606	388	17	60	633	78	634	3e-17	96.7
rs:WP_001421248	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	77	637	3e-17	96.7
tr:W4PGQ1_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.89	470	297	15	77	526	118	551	3e-17	96.7
rs:WP_027919555	DNA topoisomerase I [Pseudomonas sp. URMO17WK12:I8].	24.37	476	300	14	186	633	196	639	3e-17	96.7
rs:WP_035527058	DNA topoisomerase I [Haliea salexigens].	24.01	479	299	14	186	633	200	644	3e-17	96.7
rs:WP_001698223	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
sp:TOP1_ECOLI	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_008570827	topoisomerase I [Pseudomonas sp. Chol1].	23.58	475	305	12	186	633	193	636	3e-17	96.7
rs:WP_045417635	DNA topoisomerase I [Vibrio campbellii].	23.66	596	371	18	77	633	90	640	3e-17	96.7
rs:WP_015898448	DNA topoisomerase [Acidobacterium capsulatum].	23.32	609	393	18	55	616	29	610	3e-17	96.7
tr:K9IP36_DESRO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.24	634	397	21	3	585	5	593	3e-17	96.7
rs:WP_026443392	DNA topoisomerase [Acidobacterium sp. PMMR2].	22.64	592	356	20	83	616	61	608	3e-17	96.7
rs:WP_032221027	DNA topoisomerase 1 [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_035207854	DNA topoisomerase I [Agrobacterium tumefaciens].	22.55	705	402	29	1	630	1	636	3e-17	96.7
rs:WP_018879677	DNA topoisomerase I [Thioalkalivibrio sp. ALE9].	22.87	564	355	17	3	534	5	520	3e-17	96.7
rs:WP_002735765	DNA topoisomerase I [Microcystis aeruginosa].	24.59	610	356	21	3	560	4	561	3e-17	96.7
tr:W5JGG5_ANODA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.47	380	257	9	188	560	210	566	3e-17	96.7
rs:WP_007125556	DNA topoisomerase I [Lactobacillus ultunensis].	24.48	576	346	24	103	635	93	622	3e-17	96.3
tr:C2D5U5_LACBR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEI69841.1}; Flags: Fragment;	24.89	233	169	3	362	592	4	232	3e-17	93.2
rs:WP_019995290	DNA topoisomerase I [Aureimonas ureilytica].	23.06	707	423	28	1	643	1	650	3e-17	96.7
rs:WP_045715043	DNA topoisomerase I, partial [Salmonella enterica].	23.89	473	306	15	187	633	90	534	3e-17	96.3
rs:WP_001541847	DNA topoisomerase 1 [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_013998399	DNA topoisomerase I [Capnocytophaga canimorsus].	26.23	530	323	18	3	521	5	477	3e-17	96.7
rs:WP_042226226	DNA topoisomerase I, partial [Porphyromonas cansulci].	34.62	182	103	5	1	172	1	176	3e-17	90.9
tr:R6D1I7_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.03	620	377	22	3	596	5	556	3e-17	96.3
rs:WP_041406645	DNA topoisomerase I [Shewanella loihica].	23.50	600	371	20	74	631	88	641	3e-17	96.7
rs:WP_040991531	MULTISPECIES: DNA topoisomerase I [Vibrio].	23.14	592	385	18	75	633	85	639	3e-17	96.7
rs:WP_001646990	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_033659603	DNA topoisomerase, partial [Enterococcus faecium].	32.87	216	136	5	3	210	34	248	3e-17	92.4
rs:WP_004911045	DNA topoisomerase I subunit omega [Providencia rettgeri].	23.29	601	374	17	74	633	83	637	3e-17	96.7
tr:C8S1H8_9RHOB	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.12	651	398	26	1	611	1	595	3e-17	96.3
rs:XP_515006	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Pan troglodytes].	22.66	631	398	22	3	585	5	593	3e-17	96.7
sp:TOP3B_HUMAN	RecName: Full=DNA topoisomerase 3-beta-1; EC=5.99.1.2; AltName: Full=DNA topoisomerase III beta-1;	22.66	631	398	22	3	585	5	593	3e-17	96.7
rs:WP_031623081	DNA topoisomerase III, partial [Salmonella enterica].	29.36	235	144	7	1	223	1	225	3e-17	92.8
rs:WP_023171015	DNA topoisomerase III, partial [Salmonella enterica].	29.36	235	144	7	1	223	1	225	3e-17	92.8
rs:WP_001593985	DNA topoisomerase 1 [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
tr:A0A091IK67_CALAN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.14	566	359	19	36	564	26	552	3e-17	96.7
rs:WP_034998089	DNA topoisomerase I [Lactobacillus salivarius].	23.22	577	364	22	90	629	82	616	3e-17	96.3
rs:XP_002500244	predicted protein [Micromonas sp. RCC299].	21.76	602	397	18	3	564	8	575	3e-17	96.7
rs:WP_019532523	DNA topoisomerase I [Paenibacillus ginsengihumi].	24.12	568	367	18	103	636	80	617	3e-17	96.3
rs:WP_032191162	DNA topoisomerase 1 [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_001681014	DNA topoisomerase 1 [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.7
rs:WP_040243794	DNA topoisomerase I [Klebsiella pneumoniae].	22.61	606	388	17	60	633	78	634	3e-17	96.7
rs:WP_040233192	DNA topoisomerase I [Citrobacter sp. CIP 55.13].	23.75	598	382	22	73	633	74	634	3e-17	96.7
rs:WP_021537199	DNA topoisomerase 1 [Escherichia coli].	23.07	646	406	26	73	673	74	673	3e-17	96.7
rs:WP_003502432	DNA topoisomerase I [Agrobacterium tumefaciens].	23.50	668	389	27	38	630	16	636	3e-17	96.7
rs:WP_017724285	DNA topoisomerase I [Staphylococcus xylosus].	24.00	550	368	18	103	629	80	602	3e-17	96.3
sp:TOP3B_DROME	RecName: Full=DNA topoisomerase 3-beta; EC=5.99.1.2; AltName: Full=DNA topoisomerase III beta;	24.30	461	302	15	188	630	211	642	3e-17	96.7
rs:WP_021392297	DNA topoisomerase I [Peptoclostridium difficile].	24.93	718	414	31	3	675	5	642	3e-17	96.3
rs:WP_041569554	hypothetical protein, partial [Chloracidobacterium thermophilum].	23.62	669	399	25	3	616	5	616	3e-17	96.3
rs:WP_025649465	DNA topoisomerase I [Bacillus methylotrophicus].	23.81	567	372	21	105	641	82	618	3e-17	96.3
rs:WP_006119337	topoisomerase I [Pantoea stewartii].	22.50	600	380	18	75	633	79	634	3e-17	96.7
rs:WP_033808261	DNA topoisomerase I [Escherichia coli].	23.07	646	406	26	73	673	74	673	3e-17	96.7
tr:I2C540_BACAM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.16	567	370	21	105	641	84	620	3e-17	96.3
rs:WP_025111056	DNA topoisomerase I [Pseudomonas sp. H1h].	24.16	476	299	15	187	633	197	639	3e-17	96.7
rs:WP_023578429	DNA topoisomerase I [Flavobacterium limnosediminis].	23.95	668	386	27	3	621	5	599	3e-17	96.3
rs:WP_028550412	DNA topoisomerase I [Paenibacillus sp. UNC451MF].	23.14	566	373	22	103	636	80	615	3e-17	96.3
rs:WP_002750250	DNA topoisomerase I [Microcystis aeruginosa].	25.04	611	352	22	3	560	4	561	3e-17	96.7
rs:XP_012273642	PREDICTED: DNA topoisomerase 3-beta-1 [Orussus abietinus].	21.69	673	450	20	3	630	5	645	3e-17	96.3
tr:A0A0A9Y6R2_LYGHE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.27	597	399	18	3	560	6	570	3e-17	96.3
rs:WP_029950317	DNA topoisomerase I [Parvimonas micra].	24.18	670	397	28	3	630	5	605	3e-17	96.3
rs:WP_001428676	DNA topoisomerase 1 [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.3
rs:WP_009021608	topoisomerase I [Luminiphilus syltensis].	24.41	594	371	19	73	629	88	640	3e-17	96.7
rs:WP_012340540	topoisomerase I [Histophilus somni].	23.90	477	301	13	187	633	196	640	3e-17	96.3
rs:WP_011191333	MULTISPECIES: DNA topoisomerase [Aeromonas].	23.60	534	310	15	168	630	138	644	3e-17	95.9
rs:WP_024473153	DNA topoisomerase I [Morganella morganii].	23.48	528	318	15	187	673	188	670	3e-17	96.3
rs:WP_044731729	DNA topoisomerase I [Geobacillus kaustophilus].	24.60	504	321	17	157	630	132	606	3e-17	96.3
rs:XP_007605148	hypothetical protein VICG_01703 [Vittaforma corneae ATCC 50505].	24.48	621	382	21	3	579	4	581	3e-17	96.3
rs:WP_011219142	topoisomerase I [Photobacterium profundum].	24.50	604	358	18	76	633	88	639	3e-17	96.7
rs:WP_014017919	DNA topoisomerase I [Candidatus Arthromitus sp. SFB-mouse].	25.32	541	338	17	103	614	80	583	3e-17	96.3
rs:WP_019676957	topoisomerase I [Rheinheimera perlucida].	23.30	661	411	22	60	673	59	670	3e-17	96.3
rs:WP_033153964	DNA topoisomerase I [Pseudobutyrivibrio ruminis].	23.62	614	391	21	36	616	22	590	3e-17	96.3
rs:WP_005732652	MULTISPECIES: topoisomerase I [Pseudomonas syringae group genomosp. 2].	23.65	592	381	20	74	633	87	639	3e-17	96.3
rs:XP_006877695	PREDICTED: DNA topoisomerase 3-beta-1 [Chrysochloris asiatica].	22.65	627	403	22	3	585	5	593	3e-17	96.3
rs:WP_022760179	MULTISPECIES: DNA topoisomerase I [Butyrivibrio].	24.15	559	357	18	90	616	70	593	3e-17	96.3
rs:WP_004210738	DNA topoisomerase I subunit omega [Klebsiella pneumoniae].	22.61	606	388	17	60	633	78	634	3e-17	96.3
rs:WP_017457189	topoisomerase I [Kosakonia sacchari].	23.51	604	376	22	73	633	74	634	3e-17	96.3
rs:WP_040151502	DNA topoisomerase I [Klebsiella pneumoniae].	22.61	606	388	17	60	633	78	634	3e-17	96.3
rs:WP_019705470	topoisomerase I [Klebsiella pneumoniae].	22.73	607	386	16	60	633	78	634	3e-17	96.3
rs:WP_035845126	DNA topoisomerase I [Defluviimonas sp. 20V17].	22.91	681	414	26	1	630	1	621	3e-17	96.3
rs:WP_045955369	DNA topoisomerase I [Vibrio sp. S2757].	24.25	499	318	14	163	633	173	639	3e-17	96.3
rs:WP_023375566	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	23.89	473	306	15	187	633	40	484	3e-17	96.3
tr:A0A060VRW5_KLEPN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.61	606	388	17	60	633	80	636	3e-17	96.3
tr:F7QV08_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.22	577	364	22	90	629	40	574	3e-17	95.9
rs:WP_001554983	DNA topoisomerase 1 [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.3
rs:WP_037925496	DNA topoisomerase I [Sulfitobacter pseudonitzschiae].	22.01	736	422	28	1	660	1	660	3e-17	96.3
rs:XP_012346287	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Apis florea].	22.25	472	308	12	185	630	72	510	3e-17	96.3
rs:WP_047091085	DNA topoisomerase I, partial [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.3
rs:WP_014417765	MULTISPECIES: DNA topoisomerase I [Bacillales].	24.16	567	370	21	105	641	82	618	3e-17	96.3
rs:WP_039192312	MULTISPECIES: hypothetical protein [unclassified Thaumarchaeota (miscellaneous)].	21.30	601	413	17	3	587	5	561	3e-17	95.9
rs:WP_029285403	DNA topoisomerase I [Pedobacter sp. R20-19].	25.29	522	326	16	77	578	54	531	3e-17	96.3
rs:WP_032253403	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.3
rs:WP_001482712	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.3
rs:WP_001427498	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.3
rs:WP_040429651	DNA topoisomerase I, partial [Acidithiobacillus thiooxidans].	23.58	581	374	23	89	629	67	617	3e-17	96.3
rs:WP_027036790	DNA topoisomerase I [Mesorhizobium ciceri].	22.57	700	405	23	1	630	1	633	3e-17	96.3
rs:WP_033602881	DNA topoisomerase, partial [Enterococcus faecium].	26.97	241	155	5	293	521	84	315	3e-17	93.2
rs:WP_009384973	topoisomerase I [Vibrio sp. N418].	23.14	592	385	18	75	633	85	639	3e-17	96.3
rs:WP_007724946	DNA topoisomerase I [Carnobacterium sp. AT7].	23.80	584	370	23	90	635	68	614	3e-17	95.9
rs:WP_038988904	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.3
rs:XP_009436167	PREDICTED: DNA topoisomerase 3-beta-1 isoform X5 [Pan troglodytes].	22.66	631	398	22	3	585	5	593	3e-17	96.3
rs:WP_021023936	topoisomerase I [Salinivibrio costicola].	24.13	601	368	21	75	633	85	639	3e-17	96.3
rs:XP_010281265	PREDICTED: DNA topoisomerase 3-beta-1 [Phaethon lepturus].	23.09	563	363	18	36	564	73	599	3e-17	96.3
rs:XP_656880	DNA topoisomerase III [Entamoeba histolytica HM-1:IMSS].	24.80	637	366	25	3	581	5	586	3e-17	95.9
tr:A0A093C6P9_TAUER	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.09	563	363	18	36	564	26	552	3e-17	96.3
rs:WP_022451857	DNA topoisomerase [Clostridium sp. CAG:269].	26.00	473	297	16	88	534	62	507	3e-17	95.9
gpu:CP010446_1025	DNA topoisomerase I [Francisella tularensis subsp. tularensis str. SCHU S4 substr.]	25.50	498	307	18	154	616	1	469	3e-17	95.9
tr:I2HR12_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.16	567	370	21	105	641	84	620	3e-17	95.9
tr:K1ZG32_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.47	622	375	24	70	629	53	635	3e-17	96.3
rs:WP_019246107	DNA topoisomerase I [Candidatus Alistipes marseilloanorexicus].	23.41	534	336	16	3	520	5	481	3e-17	96.3
rs:WP_026962107	DNA topoisomerase I [Alicyclobacillus herbarius].	23.08	611	378	24	88	646	62	632	3e-17	96.3
rs:WP_004417186	DNA topoisomerase I [Pseudomonas syringae].	23.65	592	381	20	74	633	87	639	3e-17	96.3
rs:WP_021856504	DNA topoisomerase [Firmicutes bacterium CAG:555].	23.40	641	411	20	3	616	8	595	3e-17	96.3
rs:WP_021668982	DNA topoisomerase, partial [Prevotella disiens].	26.91	301	200	9	344	635	20	309	3e-17	93.2
rs:WP_041523467	DNA topoisomerase I [Gilvimarinus agarilyticus].	24.02	587	374	20	76	629	93	640	3e-17	96.3
rs:WP_019563323	DNA topoisomerase I [Thioalkalivibrio sp. ALMg2].	23.73	569	344	20	3	534	5	520	3e-17	96.3
rs:WP_032342674	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	3e-17	96.3
rs:WP_032084999	DNA topoisomerase I, partial [Escherichia coli].	23.07	646	406	26	73	673	74	673	3e-17	96.3
rs:WP_044471025	DNA topoisomerase I [Mannheimia sp. MG13].	23.99	471	308	10	187	633	196	640	3e-17	96.3
rs:WP_013037640	DNA topoisomerase I [Methanohalophilus mahii].	22.13	714	466	25	1	673	1	665	3e-17	96.3
rs:XP_004184100	DNA topoisomerase 3-beta-1, putative [Entamoeba invadens IP1].	23.56	675	430	23	3	631	4	638	3e-17	96.3
rs:WP_020804553	DNA topoisomerase I, partial [Klebsiella pneumoniae].	22.61	606	388	17	60	633	78	634	3e-17	95.9
rs:WP_016133223	DNA topoisomerase 1 [Bacillus cereus].	23.21	560	373	20	105	635	82	613	3e-17	95.9
rs:WP_036656511	DNA topoisomerase I [Paenibacillus wynnii].	23.43	589	376	23	88	636	62	615	3e-17	95.9
rs:WP_042560168	DNA topoisomerase I [Pseudomonas fluorescens].	24.11	477	300	15	186	633	196	639	3e-17	96.3
rs:WP_013846732	DNA topoisomerase I [Sphingobium chlorophenolicum].	21.48	675	423	21	1	629	1	614	4e-17	96.3
rs:WP_024843173	DNA topoisomerase I [Paracoccus pantotrophus].	22.81	719	426	28	1	659	1	650	4e-17	96.3
rs:WP_038904398	DNA topoisomerase I [Dickeya zeae].	22.71	643	405	21	75	673	87	681	4e-17	96.3
rs:WP_003706174	DNA topoisomerase I [Lactobacillus salivarius].	23.22	577	364	22	90	629	82	616	4e-17	95.9
rs:WP_011791321	DNA topoisomerase I [Desulfovibrio vulgaris].	22.31	605	373	21	76	629	53	611	4e-17	96.3
rs:WP_038866755	MULTISPECIES: DNA topoisomerase I [Vibrio].	25.38	520	286	19	163	633	174	640	4e-17	96.3
tr:E6MFE6_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.79	601	354	26	83	639	59	605	4e-17	95.9
rs:WP_023757500	DNA topoisomerase I [Mesorhizobium sp. LNHC252B00].	22.57	700	405	23	1	630	1	633	4e-17	96.3
rs:WP_032435399	DNA topoisomerase I [Klebsiella pneumoniae].	22.61	606	388	17	60	633	78	634	4e-17	96.3
rs:WP_022712311	DNA topoisomerase I [Pseudochrobactrum sp. AO18b].	23.81	693	403	28	1	629	1	632	4e-17	96.3
rs:WP_034983386	DNA topoisomerase I [Lactobacillus salivarius].	23.22	577	364	22	90	629	82	616	4e-17	95.9
tr:M4KRT9_BACIU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.59	568	374	20	105	642	84	621	4e-17	95.9
rs:WP_024370092	DNA topoisomerase I [Exiguobacterium sp. 8-11-1].	22.95	658	425	24	3	630	5	610	4e-17	95.9
rs:WP_002257107	DNA topoisomerase I [Neisseria meningitidis].	22.81	732	446	26	3	679	5	672	4e-17	96.3
rs:WP_001373327	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	4e-17	96.3
rs:WP_016514708	DNA topoisomerase 1 [Microcystis aeruginosa].	25.04	611	352	22	3	560	4	561	4e-17	96.3
rs:WP_024970798	DNA topoisomerase I [Microcystis aeruginosa].	25.04	611	352	22	3	560	4	561	4e-17	96.3
rs:WP_022304720	DNA topoisomerase [Firmicutes bacterium CAG:227].	24.64	548	341	18	103	616	80	589	4e-17	95.9
rs:XP_003502892	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Cricetulus griseus].	23.05	629	398	22	3	585	5	593	4e-17	96.3
rs:WP_038925913	DNA topoisomerase I [Dickeya zeae].	22.71	643	405	21	75	673	87	681	4e-17	96.3
rs:WP_044702697	DNA topoisomerase I [Escherichia coli].	23.93	606	371	26	73	633	74	634	4e-17	96.3
rs:WP_029741796	DNA topoisomerase I [Enterobacter asburiae].	23.12	493	309	14	168	631	138	589	4e-17	95.9
rs:WP_021588432	DNA topoisomerase I [Prevotella baroniae].	23.47	622	380	20	3	604	5	550	4e-17	96.3
rs:WP_003749245	DNA topoisomerase I [Neisseria mucosa].	22.97	727	451	26	3	679	5	672	4e-17	96.3
rs:XP_010953763	PREDICTED: DNA topoisomerase 3-beta-1 [Camelus bactrianus].	22.27	633	398	23	3	585	5	593	4e-17	96.3
rs:WP_038557105	DNA topoisomerase I [Draconibacterium orientale].	24.54	542	321	18	3	520	5	482	4e-17	96.3
rs:WP_018321114	DNA topoisomerase I [Bradyrhizobium sp. WSM2793].	23.58	704	426	24	1	647	1	649	4e-17	96.3
rs:WP_007221678	DNA topoisomerase I [planctomycete KSU-1].	23.72	607	384	18	76	640	56	625	4e-17	96.3
tr:F7RUZ0_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.16	534	325	21	186	680	195	687	4e-17	96.3
rs:WP_025951077	DNA topoisomerase I [Geobacillus thermocatenulatus].	24.86	555	358	20	105	630	82	606	4e-17	95.9
rs:WP_025119214	MULTISPECIES: DNA topoisomerase I [Serratia].	24.03	616	347	23	76	633	85	637	4e-17	96.3
rs:XP_010985627	PREDICTED: DNA topoisomerase 3-beta-1, partial [Camelus dromedarius].	22.27	633	398	23	3	585	5	593	4e-17	96.3
rs:WP_008791761	DNA topoisomerase I [Coprobacillus sp. 8_2_54BFAA].	25.61	656	359	29	2	611	4	576	4e-17	95.9
rs:WP_008688650	DNA topoisomerase I [Eubacterium sp. 3_1_31].	23.69	667	402	24	3	629	4	603	4e-17	95.9
rs:WP_003212237	DNA topoisomerase I [Bacillus pumilus].	24.42	565	366	22	103	636	80	614	4e-17	95.9
rs:WP_021308997	DNA topoisomerase I [Helicobacter pylori].	25.05	487	325	15	75	536	46	517	4e-17	95.9
rs:WP_016941328	topoisomerase I [Dickeya zeae].	22.71	643	405	21	75	673	87	681	4e-17	96.3
rs:WP_039601790	DNA topoisomerase I [Pseudomonas putida].	24.37	476	300	14	186	633	195	638	4e-17	96.3
rs:WP_034915106	DNA topoisomerase I [Erwinia sp. 9145].	22.57	669	394	26	73	680	74	679	4e-17	96.3
rs:WP_003154274	MULTISPECIES: DNA topoisomerase I [Bacillus subtilis group].	23.81	567	372	21	105	641	82	618	4e-17	95.9
rs:WP_029325907	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.16	567	370	21	105	641	82	618	4e-17	95.9
rs:WP_034957424	DNA topoisomerase I [Erythrobacter longus].	22.57	647	409	21	1	610	1	592	4e-17	96.3
rs:WP_043614100	DNA topoisomerase I [Ensifer sp. ZNC0028].	22.66	693	416	27	1	630	1	636	4e-17	96.3
rs:WP_042619786	DNA topoisomerase I [Agrobacterium tumefaciens].	23.40	671	386	27	38	630	17	637	4e-17	96.3
tr:S7SXQ4_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.86	555	358	20	105	630	105	629	4e-17	95.9
rs:XP_006065664	PREDICTED: DNA topoisomerase 3-beta-1 [Bubalus bubalis].	22.68	626	404	22	3	585	5	593	4e-17	96.3
rs:WP_017304772	DNA topoisomerase I [Spirulina subsalsa].	23.93	631	362	22	3	574	4	575	4e-17	96.3
rs:WP_046228045	DNA topoisomerase I [Paenibacillus dauci].	23.55	569	367	23	103	636	80	615	4e-17	95.9
rs:WP_044551634	DNA topoisomerase I [Serratia liquefaciens].	24.67	604	358	24	76	633	82	634	4e-17	96.3
rs:WP_045492721	DNA topoisomerase I [Vibrio sp. 151112A].	25.38	520	286	19	163	633	174	640	4e-17	96.3
rs:WP_006742126	topoisomerase I [Vibrio sp. Ex25].	23.13	588	390	16	75	633	86	640	4e-17	96.3
rs:WP_036634295	DNA topoisomerase I, partial [Paenirhodobacter enshiensis].	22.58	682	413	26	1	630	1	619	4e-17	96.3
rs:WP_008039550	DNA topoisomerase I [Bartonella tamiae].	22.59	717	428	30	1	653	1	654	4e-17	96.3
rs:WP_004378157	DNA topoisomerase I [Prevotella oris].	23.78	593	371	18	3	578	5	533	4e-17	96.3
rs:WP_021384059	DNA topoisomerase I [Peptoclostridium difficile].	25.63	632	367	27	90	675	68	642	4e-17	95.9
rs:XP_004716390	PREDICTED: DNA topoisomerase 3-beta-1 [Echinops telfairi].	22.35	631	400	21	3	585	5	593	4e-17	96.3
rs:WP_002791753	DNA topoisomerase I [Microcystis aeruginosa].	25.04	611	352	22	3	560	4	561	4e-17	96.3
rs:WP_031613111	DNA topoisomerase III, partial [Salmonella enterica].	32.78	180	106	7	1	172	1	173	4e-17	90.9
rs:WP_040931294	DNA topoisomerase I, partial [Paenibacillus larvae].	24.31	576	354	24	103	636	65	600	4e-17	95.9
rs:WP_013813135	MULTISPECIES: topoisomerase I [Serratia].	24.92	602	363	23	74	633	80	634	4e-17	96.3
rs:WP_016153252	MULTISPECIES: DNA topoisomerase 1 [Citrobacter].	23.45	597	385	22	73	633	74	634	4e-17	96.3
rs:WP_040176937	DNA topoisomerase I [Klebsiella pneumoniae].	22.48	605	390	16	60	633	78	634	4e-17	96.3
rs:WP_006698006	DNA topoisomerase I [Rhizobium lupini].	22.41	705	403	29	1	630	1	636	4e-17	96.3
tr:A0A093J4N4_FULGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.09	563	363	18	36	564	26	552	4e-17	96.3
rs:WP_039760792	DNA topoisomerase I [Pseudomonas fluorescens].	24.22	483	292	16	186	633	196	639	4e-17	96.3
rs:WP_003189652	MULTISPECIES: topoisomerase I [Pseudomonas].	23.89	473	304	13	187	633	197	639	4e-17	96.3
rs:WP_020267267	hypothetical protein [Aigarchaeota archaeon JGI 0000001-H6].	21.65	605	406	18	3	587	5	561	4e-17	95.5
gpu:CP009518_720	DNA topoisomerase I [Methanococcoides methylutens MM1]	23.87	662	430	30	1	630	1	620	4e-17	95.9
rs:WP_012601486	topoisomerase I [Escherichia coli].	24.01	604	373	25	73	633	74	634	4e-17	96.3
rs:WP_042214914	DNA topoisomerase I [Paenibacillus borealis].	23.46	584	382	20	88	636	62	615	4e-17	95.9
rs:WP_007307655	DNA topoisomerase I [Crocosphaera watsonii].	23.78	656	392	22	1	610	1	594	4e-17	95.9
rs:WP_004847177	DNA topoisomerase I [[Ruminococcus] torques].	23.34	647	401	23	3	616	5	589	4e-17	95.9
tr:A3QF42_SHELP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.50	600	371	20	74	631	104	657	4e-17	96.3
rs:WP_018949196	DNA topoisomerase I [Thioalkalivibrio sp. ALMg11].	23.90	569	343	20	3	534	5	520	4e-17	96.3
rs:WP_004520185	DNA topoisomerase I [Neisseria subflava].	23.11	727	450	26	3	679	5	672	4e-17	95.9
rs:WP_007409771	MULTISPECIES: DNA topoisomerase I [Bacillus].	23.81	567	372	21	105	641	82	618	4e-17	95.9
tr:C6HWV0_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.91	680	422	24	3	631	50	671	4e-17	96.3
rs:WP_014118434	DNA topoisomerase I [Oscillibacter valericigenes].	22.94	632	390	20	90	673	68	650	4e-17	96.3
tr:A0A093FNA9_GAVST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.09	563	363	18	36	564	26	552	4e-17	96.3
rs:WP_046483688	DNA topoisomerase I [Oceanospirillaceae bacterium ASP10-02a].	24.17	600	361	24	77	633	94	642	4e-17	96.3
rs:WP_035081584	DNA topoisomerase I [Caulobacter henricii].	21.38	697	409	24	1	629	1	626	4e-17	96.3
rs:WP_003427121	DNA topoisomerase I subunit omega [Pseudomonas syringae].	23.82	592	380	20	74	633	87	639	4e-17	96.3
rs:WP_027663457	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	4e-17	96.3
rs:WP_026660394	DNA topoisomerase I [Butyrivibrio sp. AC2005].	24.60	557	357	19	90	616	70	593	4e-17	95.9
rs:WP_024551692	DNA topoisomerase I [Cronobacter helveticus].	23.37	599	383	16	73	633	75	635	4e-17	96.3
rs:WP_033025076	DNA topoisomerase I [Geobacillus sp. CAMR5420].	24.70	502	323	16	157	630	132	606	4e-17	95.9
tr:A0A091U3E4_PHORB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.09	563	363	18	36	564	26	552	4e-17	96.3
rs:WP_035472386	DNA topoisomerase I [Alistipes sp. 627].	25.36	552	339	20	74	604	45	544	4e-17	95.9
rs:WP_007648109	DNA topoisomerase I [Formosa sp. AK20].	24.11	535	328	16	3	521	5	477	4e-17	96.3
rs:XP_007130667	PREDICTED: DNA topoisomerase 3-beta-1 [Physeter catodon].	23.02	630	397	22	3	585	5	593	4e-17	96.3
rs:WP_022008214	DNA topoisomerase [Coprobacillus sp. CAG:183].	25.61	656	359	29	2	611	4	576	4e-17	95.9
rs:WP_005742386	DNA topoisomerase III [Pseudomonas amygdali].	22.44	704	409	24	4	586	6	693	4e-17	96.3
rs:WP_047134706	DNA topoisomerase I [bacterium JGI-5].	24.51	616	361	22	74	634	61	627	4e-17	95.9
rs:WP_027132250	DNA topoisomerase I [Fusobacterium necrophorum].	26.62	601	323	24	3	561	6	530	4e-17	95.9
rs:WP_024944133	DNA topoisomerase I [Aeromonas hydrophila].	24.09	606	363	22	75	633	82	637	4e-17	96.3
tr:A0A0A0AQK4_CHAVO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.09	563	363	18	36	564	26	552	4e-17	96.3
rs:WP_046128972	DNA topoisomerase I [Bacillus sp. TH008].	24.06	561	367	21	105	635	82	613	4e-17	95.9
rs:WP_045825790	DNA topoisomerase I [Teredinibacter sp. 991H.S.0a.06].	24.09	606	374	22	65	629	80	640	4e-17	96.3
rs:WP_005703159	topoisomerase I [Aggregatibacter aphrophilus].	23.62	470	311	10	187	633	196	640	4e-17	96.3
tr:G4EWD2_BACIU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.59	568	374	20	105	642	75	612	4e-17	95.9
rs:WP_038913983	DNA topoisomerase I [Dickeya zeae].	22.71	643	405	21	75	673	87	681	4e-17	96.3
rs:WP_041517853	DNA topoisomerase I [Bacillus subtilis].	23.59	568	374	20	105	642	82	619	4e-17	95.9
rs:WP_015374403	MULTISPECIES: DNA topoisomerase I [Geobacillus].	24.86	555	358	20	105	630	82	606	4e-17	95.9
rs:WP_040205353	DNA topoisomerase III, partial [Klebsiella pneumoniae].	28.48	309	190	14	1	287	1	300	4e-17	92.8
rs:WP_035491918	DNA topoisomerase I [Gammaproteobacteria bacterium MOLA455].	24.45	589	358	21	83	629	100	643	4e-17	96.3
rs:XP_001470217	putative DNA topoisomerase III [Leishmania infantum JPCM5].	21.71	608	397	18	3	571	6	573	4e-17	96.3
sp:TOP1_PASMU	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.79	476	294	15	187	631	196	638	4e-17	96.3
rs:WP_026515776	DNA topoisomerase I [Butyrivibrio sp. MC2021].	24.51	567	345	20	90	616	61	584	4e-17	95.9
rs:WP_038696754	DNA topoisomerase I [Paenibacillus stellifer].	22.81	605	396	20	103	675	80	645	4e-17	95.9
rs:WP_026651296	DNA topoisomerase I [Butyrivibrio proteoclasticus].	24.51	559	355	21	90	616	74	597	4e-17	95.9
tr:H4GHS5_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.37	569	373	19	90	629	86	620	4e-17	95.9
rs:WP_046381022	DNA topoisomerase I [Bacillus sp. LM 4-2].	23.59	568	374	20	105	642	82	619	4e-17	95.9
rs:WP_029168316	DNA topoisomerase I [alpha proteobacterium SCGC AAA023-L09].	23.44	640	383	25	1	597	1	576	4e-17	95.9
rs:WP_045079058	DNA topoisomerase I [Vitellibacter vladivostokensis].	26.17	554	337	18	3	539	5	503	4e-17	95.9
rs:WP_040578076	DNA topoisomerase I, partial [Methylophilales bacterium HTCC2181].	23.29	674	413	23	2	630	3	617	4e-17	95.9
rs:XP_001739303	DNA topoisomerase 3-alpha [Entamoeba dispar SAW760].	24.65	637	367	26	3	581	5	586	4e-17	95.5
tr:A0A0C7C736_9FUNG	SubName: Full=RMATCC62417_13354 protein {ECO:0000313|EMBL:CEG78807.1};	22.55	501	322	17	163	631	17	483	4e-17	95.9
rs:WP_018873178	DNA topoisomerase I [Thioalkalivibrio sp. ALJ16].	22.74	563	357	17	3	534	5	520	4e-17	95.9
rs:WP_023570754	DNA topoisomerase I [Flavobacterium cauense].	25.00	532	327	20	3	521	5	477	4e-17	95.9
rs:WP_007524326	topoisomerase I [Haemophilus sputorum].	23.25	585	385	19	74	629	87	636	4e-17	96.3
rs:WP_014994167	topoisomerase I [Alcanivorax dieselolei].	23.12	480	307	14	186	631	200	651	4e-17	96.3
rs:WP_036587972	DNA topoisomerase I [Paenibacillus sophorae].	22.91	585	384	21	88	636	62	615	4e-17	95.9
rs:WP_022217580	DNA topoisomerase [Bacteroides clarus CAG:160].	24.08	623	373	22	3	596	5	556	4e-17	95.9
rs:WP_021907930	DNA topoisomerase [Eubacterium sp. CAG:146].	24.24	561	353	17	90	616	67	589	4e-17	95.9
tr:A0P4J6_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.29	674	413	23	2	630	3	617	4e-17	95.9
tr:H1DE39_9PORP	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHP50836.1};	32.52	206	124	7	479	680	1	195	4e-17	91.3
rs:WP_020330226	DNA topoisomerase I [Vibrio fluvialis].	25.10	502	310	13	163	633	176	642	4e-17	95.9
gp:CP002906_1692	DNA topoisomerase I [Bacillus subtilis subsp. subtilis str. RO-NN-1]	23.59	568	374	20	105	642	84	621	4e-17	95.9
rs:WP_009262778	DNA topoisomerase I [Lachnospiraceae bacterium 9_1_43BFAA].	24.01	554	363	17	90	616	67	589	4e-17	95.9
rs:WP_001497537	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	4e-17	95.9
rs:WP_031572692	DNA topoisomerase I [Acidithiobacillus thiooxidans].	23.30	588	367	23	89	629	67	617	4e-17	95.9
rs:WP_031368241	hypothetical protein, partial [Clostridium botulinum].	31.23	253	148	11	184	420	8	250	4e-17	92.4
rs:WP_011706893	DNA topoisomerase I [Aeromonas hydrophila].	24.09	606	363	22	75	633	82	637	4e-17	95.9
rs:WP_042102551	DNA topoisomerase III, partial [Escherichia coli].	32.78	180	108	6	1	173	1	174	4e-17	90.5
rs:WP_004093343	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	4e-17	95.9
rs:WP_042318669	DNA topoisomerase I [Citrobacter farmeri].	23.21	599	384	19	73	633	74	634	4e-17	95.9
tr:A0A091VC14_OPIHO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.27	563	362	18	36	564	26	552	4e-17	95.9
rs:WP_010784903	DNA topoisomerase 1 [Enterococcus faecalis].	25.18	564	347	24	103	629	81	606	4e-17	95.9
rs:WP_009169157	DNA topoisomerase I [Clostridium sp. DL-VIII].	24.15	650	391	24	2	616	4	586	4e-17	95.9
rs:WP_005600147	topoisomerase I [Vibrio scophthalmi].	23.31	592	384	18	75	633	85	639	4e-17	95.9
gp:CP003695_2276	DNA topoisomerase I [Bacillus subtilis subsp. subtilis str. BSP1]	23.59	568	374	20	105	642	87	624	4e-17	95.9
gp:CP007024_751	DNA topoisomerase I [Streptococcus pyogenes STAB901]	23.04	560	357	19	103	629	103	621	4e-17	95.9
rs:WP_013857079	topoisomerase I [Vibrio anguillarum].	24.85	511	300	16	163	633	174	640	4e-17	95.9
rs:WP_038641850	DNA topoisomerase I [Pasteurella multocida].	24.79	476	294	15	187	631	196	638	4e-17	95.9
rs:WP_007006749	DNA topoisomerase I [Nitratireductor aquibiodomus].	21.71	700	411	27	1	630	1	633	4e-17	95.9
rs:WP_029321743	DNA topoisomerase I [Butyrivibrio sp. AE3004].	23.74	556	362	17	90	616	70	592	4e-17	95.9
tr:A0A093RLU4_PYGAD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.09	563	363	18	36	564	26	552	4e-17	95.9
rs:WP_026187416	DNA topoisomerase I [Ensifer sp. BR816].	23.05	694	412	29	1	630	1	636	4e-17	95.9
rs:WP_032080259	DNA topoisomerase I [Vibrio fluvialis].	25.10	502	310	13	163	633	176	642	4e-17	95.9
rs:WP_036491339	DNA topoisomerase I [Neisseria mucosa].	22.97	727	451	26	3	679	5	672	4e-17	95.9
rs:WP_040639880	DNA topoisomerase I [Pseudoramibacter alactolyticus].	24.79	601	354	26	83	639	60	606	4e-17	95.5
rs:WP_007149281	topoisomerase I [Alcanivorax sp. DG881].	23.28	610	386	23	65	631	79	649	4e-17	95.9
rs:WP_045149545	DNA topoisomerase I [Escherichia coli].	23.63	601	379	23	73	633	74	634	4e-17	95.9
rs:WP_005780640	topoisomerase I [Pseudomonas amygdali].	23.68	604	366	20	74	633	87	639	5e-17	95.9
rs:WP_044294085	DNA topoisomerase I [Robinsoniella peoriensis].	23.54	565	353	20	90	616	67	590	5e-17	95.5
rs:WP_029161493	DNA topoisomerase I [Clostridium scatologenes].	24.27	651	391	23	2	616	4	588	5e-17	95.9
rs:WP_039111492	DNA topoisomerase I [Flavobacterium sp. KMS].	25.52	533	323	21	3	521	5	477	5e-17	95.9
rs:WP_024644067	DNA topoisomerase I [Pseudomonas syringae].	23.65	592	381	20	74	633	87	639	5e-17	95.9
rs:WP_044721998	DNA topoisomerase 1 [Escherichia coli].	23.79	601	378	24	73	633	74	634	5e-17	95.9
rs:XP_001709794	DNA topoisomerase III [Giardia lamblia ATCC 50803].	23.68	642	416	27	1	589	1	621	5e-17	96.3
rs:WP_012526797	DNA topoisomerase I [Anaeromyxobacter sp. K].	24.01	633	383	25	76	646	97	693	5e-17	95.9
rs:WP_022072993	DNA topoisomerase [Anaerotruncus sp. CAG:528].	23.47	652	399	24	2	616	3	591	5e-17	95.5
rs:WP_034495665	DNA topoisomerase I [Buttiauxella agrestis].	24.17	604	372	24	73	633	74	634	5e-17	95.9
rs:WP_001643336	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	5e-17	95.9
rs:WP_042223781	DNA topoisomerase I [Oceanobacillus manasiensis].	25.04	571	354	21	103	635	80	614	5e-17	95.5
rs:WP_022146067	DNA topoisomerase [Firmicutes bacterium CAG:238].	24.68	539	346	16	103	616	96	599	5e-17	95.5
rs:WP_027547207	DNA topoisomerase I [Bradyrhizobium sp. WSM2254].	23.18	686	417	23	1	630	1	632	5e-17	95.9
rs:WP_009009111	MULTISPECIES: DNA topoisomerase I [Coprobacillus].	25.61	656	359	29	2	611	4	576	5e-17	95.5
rs:WP_038434096	DNA topoisomerase I [Streptococcus pyogenes].	23.04	560	357	19	103	629	103	621	5e-17	95.5
rs:WP_016279166	DNA topoisomerase I [Lachnospiraceae bacterium A4].	24.19	558	357	17	90	616	67	589	5e-17	95.5
rs:WP_010699175	DNA topoisomerase I [Treponema denticola].	24.54	546	336	22	163	675	157	659	5e-17	95.9
rs:WP_003538227	DNA topoisomerase I [Erysipelatoclostridium ramosum].	25.61	656	359	29	2	611	4	576	5e-17	95.5
rs:WP_008287467	DNA topoisomerase I [Hydrogenivirga sp. 128-5-R1-1].	22.32	596	371	17	1	574	1	526	5e-17	95.1
rs:WP_037063478	DNA topoisomerase I [Rhizobium leguminosarum].	24.78	670	378	32	38	630	16	636	5e-17	95.9
rs:WP_011093844	topoisomerase I [Pectobacterium atrosepticum].	23.68	625	362	23	57	633	78	635	5e-17	95.9
rs:WP_039332040	DNA topoisomerase I [Novosphingobium subterraneum].	22.16	677	419	25	1	629	1	617	5e-17	95.9
rs:WP_040152275	DNA topoisomerase III, partial [Xanthomonas citri].	29.48	173	115	3	1	172	1	167	5e-17	90.5
rs:WP_024641788	DNA topoisomerase I [Pseudomonas syringae].	23.65	592	381	20	74	633	87	639	5e-17	95.9
rs:WP_040467782	DNA topoisomerase I [Lactobacillus gastricus].	23.37	569	373	19	90	629	96	630	5e-17	95.5
rs:WP_042203615	DNA topoisomerase I [Escherichia coli].	23.41	598	384	23	73	633	74	634	5e-17	95.9
rs:WP_022937729	DNA topoisomerase I [Dielma fastidiosa].	24.09	660	376	25	2	614	3	584	5e-17	95.9
rs:WP_038428950	DNA topoisomerase I [Bacillus subtilis].	23.59	568	374	20	105	642	82	619	5e-17	95.5
rs:WP_032349710	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	5e-17	95.9
rs:WP_001484824	topoisomerase I [Escherichia coli].	23.66	596	385	22	73	633	74	634	5e-17	95.9
rs:XP_008859836	DNA topoisomerase domain containing protein [Entamoeba nuttalli P19].	24.80	637	366	25	3	581	5	586	5e-17	95.5
rs:WP_024968195	DNA topoisomerase I [Pantoea sp. IMH].	22.44	655	412	21	57	673	77	673	5e-17	95.9
rs:WP_008203491	DNA topoisomerase I [Microcystis sp. T1-4].	25.04	611	352	22	3	560	4	561	5e-17	95.9
rs:WP_018882556	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	22.87	564	355	17	3	534	5	520	5e-17	95.9
rs:WP_011789092	topoisomerase I [Shewanella sp. W3-18-1].	23.54	480	298	16	186	631	197	641	5e-17	95.9
tr:A0A075JPQ3_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AIF42093.1};	27.89	251	174	4	443	686	57	307	5e-17	92.8
rs:WP_038661211	DNA topoisomerase I [Pseudomonas stutzeri].	23.85	478	298	13	187	633	194	636	5e-17	95.9
rs:WP_008538386	DNA topoisomerase I [Megamonas funiformis].	22.67	600	368	20	90	636	69	625	5e-17	95.9
rs:WP_023634013	DNA topoisomerase I [Geobacillus sp. MAS1].	24.70	502	323	16	157	630	132	606	5e-17	95.5
rs:WP_017184447	DNA topoisomerase I [Sphingobium xenophagum].	22.39	670	423	22	1	629	1	614	5e-17	95.9
rs:WP_029335400	DNA topoisomerase I [Exiguobacterium aurantiacum].	22.98	657	426	23	3	630	5	610	5e-17	95.5
rs:WP_024684404	DNA topoisomerase I [Pseudomonas syringae].	23.65	592	381	20	74	633	87	639	5e-17	95.9
rs:WP_001460827	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	5e-17	95.9
rs:WP_017049879	topoisomerase I [Vibrio ordalii].	24.85	511	300	16	163	633	174	640	5e-17	95.9
rs:WP_025457058	DNA topoisomerase I [Neisseria polysaccharea].	22.83	727	452	26	3	679	5	672	5e-17	95.9
rs:WP_025245756	DNA topoisomerase I [Candidatus Sodalis pierantonius].	23.64	588	388	17	74	633	77	631	5e-17	95.9
rs:WP_040226445	DNA topoisomerase I [Klebsiella pneumoniae].	22.61	606	388	17	60	633	78	634	5e-17	95.9
rs:WP_001680391	topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	5e-17	95.9
rs:WP_046193505	DNA topoisomerase I [Sphingomonas sp. SRS2].	22.04	676	418	21	1	629	1	614	5e-17	95.9
rs:WP_014610724	topoisomerase I [Shewanella putrefaciens].	23.54	480	298	16	186	631	197	641	5e-17	95.9
rs:XP_011354260	PREDICTED: DNA topoisomerase 3-beta-1 [Pteropus vampyrus].	22.35	631	400	21	3	585	5	593	5e-17	95.9
rs:WP_033897283	DNA topoisomerase I [Pseudomonas sp. FH1].	23.65	482	313	11	77	537	62	509	5e-17	95.5
rs:WP_040186246	DNA topoisomerase I [Halomonas salina].	24.63	609	355	24	76	633	94	649	5e-17	95.9
rs:WP_009669777	topoisomerase I [gamma proteobacterium IMCC1989].	23.84	604	382	20	65	631	80	642	5e-17	95.9
rs:WP_042975774	DNA topoisomerase 1 [Bacillus subtilis].	23.59	568	374	20	105	642	82	619	5e-17	95.5
tr:A0A061PJJ8_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.30	588	389	16	75	633	87	641	5e-17	95.9
rs:WP_039217791	DNA topoisomerase I [Clostridium novyi].	24.34	645	396	21	2	616	4	586	5e-17	95.5
rs:WP_021958984	DNA topoisomerase [Brachyspira sp. CAG:700].	23.98	659	413	26	2	629	20	621	5e-17	95.5
sp:TOP1_BACSU	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	23.59	568	374	20	105	642	82	619	5e-17	95.5
rs:WP_016534517	DNA topoisomerase I subunit omega [Pasteurella multocida].	24.79	476	294	15	187	631	196	638	5e-17	95.9
rs:WP_003710032	DNA topoisomerase I [Lactobacillus salivarius].	23.22	577	364	22	90	629	82	616	5e-17	95.5
rs:XP_008945305	PREDICTED: DNA topoisomerase 3-beta-1, partial [Merops nubicus].	24.81	395	248	11	188	564	146	509	5e-17	95.9
rs:XP_008333802	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Cynoglossus semilaevis].	22.29	637	393	20	3	585	5	593	5e-17	95.9
rs:WP_009246427	DNA topoisomerase I [Lachnospiraceae bacterium 6_1_63FAA].	24.23	553	337	19	103	616	80	589	5e-17	95.5
rs:WP_041216392	DNA topoisomerase I [Aeromonas hydrophila].	24.26	606	362	22	75	633	82	637	5e-17	95.9
rs:WP_012388160	DNA topoisomerase I [Leptospira biflexa].	24.13	543	347	15	87	598	39	547	5e-17	95.5
rs:WP_014076565	DNA topoisomerase I [Sphingobium sp. SYK-6].	22.40	674	429	22	1	630	1	624	5e-17	95.9
rs:WP_025248461	DNA topoisomerase I [Pasteurella multocida].	24.79	476	294	15	187	631	196	638	5e-17	95.9
rs:WP_033886444	DNA topoisomerase I, partial [Bacteroides faecichinchillae].	24.64	552	351	17	76	604	53	562	5e-17	95.5
rs:WP_027297021	DNA topoisomerase I [Robinsoniella sp. KNHs210].	23.54	565	353	20	90	616	67	590	5e-17	95.5
rs:XP_012571821	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Cicer arietinum].	23.05	551	369	14	105	631	55	574	5e-17	95.9
rs:WP_028126135	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	5e-17	95.9
rs:WP_028629481	DNA topoisomerase I [Pseudomonas resinovorans].	23.27	593	382	17	74	633	85	637	5e-17	95.9
rs:WP_037419529	DNA topoisomerase I [Shewanella xiamenensis].	23.65	482	293	16	187	631	198	641	5e-17	95.9
rs:XP_011587889	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Aquila chrysaetos canadensis].	23.09	563	363	18	36	564	24	550	5e-17	95.9
rs:WP_017044653	topoisomerase I [Vibrio ordalii].	24.85	511	300	16	163	633	174	640	5e-17	95.9
tr:A0A091R8G6_MERNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.81	395	248	11	188	564	147	510	5e-17	95.9
rs:WP_020827133	topoisomerase I [Serratia liquefaciens].	24.67	604	358	24	76	633	82	634	5e-17	95.9
rs:WP_039291757	DNA topoisomerase I [Pectobacterium atrosepticum].	23.85	608	362	21	74	633	81	635	5e-17	95.9
rs:WP_001714078	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	5e-17	95.9
rs:XP_011276511	DNA topoisomerase III [Wickerhamomyces ciferrii].	22.05	653	413	19	3	599	4	616	5e-17	95.1
rs:WP_040550400	DNA topoisomerase I [Pyramidobacter piscolens].	22.44	722	435	27	3	680	16	656	5e-17	95.5
rs:WP_022227777	DNA topoisomerase [Megamonas funiformis CAG:377].	22.67	600	368	20	90	636	69	625	5e-17	95.5
rs:WP_001394200	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	5e-17	95.9
rs:WP_021479296	DNA topoisomerase 1 [Bacillus sp. EGD-AK10].	23.59	568	374	20	105	642	82	619	5e-17	95.5
tr:W4LII3_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.13	576	356	20	83	616	60	596	5e-17	95.5
rs:WP_017043915	topoisomerase I [Vibrio ordalii].	24.85	511	300	16	163	633	174	640	5e-17	95.9
rs:WP_034570232	hypothetical protein [Helicobacter sanguini].	25.38	532	325	17	76	575	48	539	5e-17	95.5
rs:WP_003697687	DNA topoisomerase I [Neisseria gonorrhoeae].	22.56	727	454	25	3	679	5	672	5e-17	95.5
rs:WP_001661269	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	5e-17	95.9
rs:WP_010320022	topoisomerase I [Vibrio ordalii].	25.05	511	299	16	163	633	174	640	5e-17	95.9
rs:WP_037415810	DNA topoisomerase I [Serratia grimesii].	24.50	604	359	24	76	633	84	636	5e-17	95.9
rs:WP_033568758	DNA topoisomerase I [Dickeya sp. 2B12].	23.00	639	404	22	76	673	84	675	5e-17	95.9
rs:WP_005751468	topoisomerase I [Pasteurella multocida].	24.79	476	294	15	187	631	196	638	5e-17	95.9
rs:WP_019558996	DNA topoisomerase I [Thioalkalivibrio sp. ALE12].	22.87	564	355	17	3	534	5	520	5e-17	95.9
rs:WP_029304161	DNA topoisomerase I [Aeromonas hydrophila].	24.26	606	362	22	75	633	82	637	5e-17	95.9
rs:WP_029399852	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	5e-17	95.9
rs:WP_021518134	DNA topoisomerase 1 [Escherichia coli].	23.84	604	374	25	73	633	74	634	5e-17	95.9
rs:WP_036159917	DNA topoisomerase I [Marinomonas ushuaiensis].	22.26	647	400	20	74	673	90	680	5e-17	95.9
tr:L0LHC8_RHITR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.91	659	404	25	38	630	18	638	5e-17	95.9
rs:WP_043160059	DNA topoisomerase I [Aeromonas hydrophila].	24.26	606	362	22	75	633	82	637	5e-17	95.9
rs:WP_006321120	topoisomerase I [Serratia plymuthica].	24.79	597	370	20	74	633	80	634	5e-17	95.9
rs:WP_001468644	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	5e-17	95.9
rs:WP_044124813	DNA topoisomerase I, partial [Prevotella loescheii].	31.53	222	140	7	455	673	50	262	5e-17	92.4
rs:WP_036105783	DNA topoisomerase I [Lysobacter capsici].	23.32	579	344	19	3	538	5	526	5e-17	95.9
rs:WP_039980762	DNA topoisomerase I [Vibrio sagamiensis].	23.36	595	384	18	73	633	84	640	5e-17	95.9
rs:WP_017047729	topoisomerase I [Vibrio ordalii].	24.85	511	300	16	163	633	174	640	5e-17	95.9
rs:WP_040260718	DNA topoisomerase I [Pseudomonas sp. CB1].	24.29	597	362	23	74	629	85	632	5e-17	95.9
rs:WP_024788245	MULTISPECIES: DNA topoisomerase I [Lebetimonas].	25.00	656	399	24	3	629	5	596	5e-17	95.5
rs:XP_010850479	PREDICTED: DNA topoisomerase 3-beta-1 [Bison bison bison].	22.58	629	401	22	3	585	5	593	5e-17	95.9
rs:WP_040063189	DNA topoisomerase I [Pseudomonas batumici].	22.78	474	310	12	186	633	196	639	5e-17	95.9
rs:WP_001391746	DNA topoisomerase I [Escherichia coli].	23.92	602	376	24	73	633	74	634	5e-17	95.9
rs:WP_011230711	MULTISPECIES: DNA topoisomerase I [Geobacillus].	24.70	502	323	16	157	630	132	606	5e-17	95.5
rs:XP_012528257	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Monomorium pharaonis].	20.77	679	449	21	3	630	5	645	5e-17	95.9
rs:WP_044800504	DNA topoisomerase I [Aeromonas hydrophila].	24.26	606	362	22	75	633	82	637	5e-17	95.9
rs:WP_001309471	MULTISPECIES: DNA topoisomerase I [Escherichia].	23.63	601	379	24	73	633	74	634	5e-17	95.9
rs:WP_039743749	DNA topoisomerase I [Geobacter pickeringii].	22.89	712	436	28	3	658	5	659	5e-17	95.5
rs:WP_014470402	MULTISPECIES: DNA topoisomerase I [Bacillus subtilis group].	23.63	567	373	21	105	641	82	618	5e-17	95.5
rs:WP_042824672	DNA topoisomerase III, partial [Xanthomonas axonopodis].	27.63	228	158	3	358	582	5	228	6e-17	91.3
rs:WP_021321700	DNA topoisomerase I [Geobacillus sp. A8].	24.70	502	323	16	157	630	132	606	6e-17	95.5
rs:WP_046658174	DNA topoisomerase I [Lysobacter capsici].	23.32	579	344	19	3	538	5	526	6e-17	95.5
rs:WP_019584255	DNA topoisomerase I [Thioalkalivibrio sp. ALE16].	22.87	564	355	17	3	534	5	520	6e-17	95.9
rs:WP_022962362	topoisomerase I [Pseudomonas pelagia].	23.04	599	378	19	74	633	84	638	6e-17	95.9
rs:WP_045527759	DNA topoisomerase I [Aeromonas hydrophila].	24.26	606	362	22	75	633	82	637	6e-17	95.9
rs:WP_003108440	DNA topoisomerase I [Streptococcus parauberis].	22.97	579	374	22	83	629	84	622	6e-17	95.5
rs:XP_007225278	hypothetical protein PRUPE_ppa001428mg [Prunus persica].	23.94	614	364	27	64	610	64	641	6e-17	95.5
rs:WP_047242530	DNA topoisomerase I [Enterococcus cecorum].	24.60	569	358	24	103	635	81	614	6e-17	95.5
rs:WP_012771455	topoisomerase I [Aggregatibacter aphrophilus].	23.24	469	314	9	187	633	196	640	6e-17	95.9
rs:WP_034795369	DNA topoisomerase I [Ensifer adhaerens].	22.37	693	418	26	1	630	1	636	6e-17	95.9
rs:WP_024212192	DNA topoisomerase I [Escherichia sp. TW15838].	23.63	601	379	24	73	633	74	634	6e-17	95.5
rs:WP_016252326	DNA topoisomerase 1 [Enterococcus cecorum].	24.60	569	358	24	103	635	81	614	6e-17	95.5
rs:WP_005700469	topoisomerase I [Aggregatibacter aphrophilus].	23.24	469	314	9	187	633	196	640	6e-17	95.5
rs:WP_042380537	DNA topoisomerase I [Geobacillus kaustophilus].	24.70	502	323	16	157	630	132	606	6e-17	95.5
rs:WP_019714400	DNA topoisomerase I [Bacillus subtilis].	23.74	514	338	17	157	642	132	619	6e-17	95.5
rs:WP_044362274	DNA topoisomerase I [Vibrio fluvialis].	25.10	502	310	13	163	633	176	642	6e-17	95.5
rs:WP_008043313	topoisomerase I [Reinekea blandensis].	23.10	580	385	16	77	629	94	639	6e-17	95.9
tr:F4TDH0_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.63	601	379	24	73	633	88	648	6e-17	95.5
tr:G2LH23_CHLTF	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.70	671	396	26	3	616	5	616	6e-17	95.5
tr:G8F1W3_MACMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.66	631	398	22	3	585	5	593	6e-17	95.5
rs:WP_041018111	DNA topoisomerase I [Criblamydia sequanensis].	25.55	497	305	16	82	536	59	532	6e-17	95.5
tr:A0A073KNM5_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.65	482	293	16	187	631	214	657	6e-17	95.9
rs:WP_039020811	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	6e-17	95.5
rs:WP_015030876	DNA topoisomerase I [Emticicia oligotrophica].	24.95	537	322	18	3	520	5	479	6e-17	95.5
rs:WP_038247321	DNA topoisomerase I [Zetaproteobacteria bacterium TAG-1].	23.56	679	420	25	3	639	4	625	6e-17	95.5
sp:TOP1_SYNY3	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	23.91	619	375	20	2	572	3	573	6e-17	95.9
rs:WP_040199198	DNA topoisomerase I [Geoalkalibacter subterraneus].	23.22	715	411	31	3	649	5	649	6e-17	95.5
rs:WP_025706262	DNA topoisomerase I [Paenibacillus graminis].	23.54	582	384	21	88	636	62	615	6e-17	95.5
rs:WP_008967069	DNA topoisomerase I [Bradyrhizobium sp. STM 3843].	24.28	692	402	30	1	630	1	632	6e-17	95.9
rs:WP_019605119	topoisomerase I [Teredinibacter turnerae].	23.93	606	375	22	65	629	80	640	6e-17	95.5
rs:WP_004945205	topoisomerase I [Serratia plymuthica].	24.79	597	370	20	74	633	80	634	6e-17	95.5
rs:WP_014668030	topoisomerase I [Pasteurella multocida].	24.79	476	294	15	187	631	196	638	6e-17	95.5
rs:WP_019627543	DNA topoisomerase I [Thioalkalivibrio sp. AKL10].	23.55	569	345	20	3	534	5	520	6e-17	95.5
tr:I7L3U8_NEIME	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.95	732	445	27	3	679	58	725	6e-17	95.5
rs:WP_021518705	DNA topoisomerase 1 [Escherichia coli].	23.79	601	378	24	73	633	74	634	6e-17	95.5
rs:WP_034276053	DNA topoisomerase III, partial [Bacillus sp. 171095_106].	25.29	344	220	11	358	675	1	333	6e-17	92.8
tr:A0A0D5ZFV8_9ARCH	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:AKA48510.1};	25.16	640	366	30	2	591	4	580	6e-17	95.5
rs:WP_001390153	DNA topoisomerase I [Escherichia coli].	23.92	602	376	24	73	633	74	634	6e-17	95.5
rs:WP_014085710	DNA topoisomerase I [Pseudogulbenkiania sp. NH8B].	23.08	663	420	24	3	630	5	612	6e-17	95.5
rs:WP_021580713	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	6e-17	95.5
tr:A0A084VTN2_9DIPT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.45	592	405	17	1	560	3	566	6e-17	95.5
rs:WP_019628805	topoisomerase I [Moritella marina].	23.90	590	379	20	77	633	93	645	6e-17	95.5
rs:WP_015158955	DNA topoisomerase I [Chamaesiphon minutus].	23.95	572	362	18	81	614	61	597	6e-17	95.5
rs:WP_018919763	DNA topoisomerase I [Prevotella oris].	23.78	593	371	18	3	578	5	533	6e-17	95.5
rs:XP_010673317	PREDICTED: DNA topoisomerase 3-beta isoform X3 [Beta vulgaris subsp. vulgaris].	22.26	557	370	16	105	631	31	554	6e-17	95.5
rs:WP_016986750	topoisomerase I [Pseudomonas fluorescens].	24.11	477	300	15	186	633	196	639	6e-17	95.5
rs:WP_042664349	hypothetical protein [Aigarchaeota archaeon SCGC AAA471-F17].	21.65	605	406	18	3	587	5	561	6e-17	95.1
rs:WP_006363417	DNA topoisomerase I [Gemella sanguinis].	24.08	569	342	21	103	629	81	601	6e-17	95.1
rs:WP_002239431	DNA topoisomerase I [Neisseria meningitidis].	22.97	727	451	26	3	679	5	672	6e-17	95.5
rs:XP_008333800	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Cynoglossus semilaevis].	22.29	637	393	20	3	585	5	593	6e-17	95.5
tr:A6VX57_MARMS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.33	596	372	19	74	633	90	642	6e-17	95.5
tr:A0A091NQJ5_APAVI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.09	563	363	18	36	564	26	552	6e-17	95.5
rs:WP_010579950	DNA topoisomerase I [Lactobacillus vini].	23.05	603	375	21	90	645	83	643	6e-17	95.1
rs:WP_018613933	hypothetical protein [Segetibacter koreensis].	26.30	559	328	20	3	539	5	501	6e-17	95.5
tr:D6J9Q0_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.63	601	379	24	73	633	76	636	6e-17	95.5
rs:WP_041064802	DNA topoisomerase I [Cohnella sp. VKM B-2846].	24.14	584	379	23	88	636	62	616	6e-17	95.1
rs:WP_008082212	topoisomerase I [Pseudomonas sp. GM80].	24.11	477	300	15	186	633	196	639	6e-17	95.5
rs:WP_023445655	topoisomerase I [Pseudomonas chloritidismutans].	23.43	478	300	12	187	633	194	636	6e-17	95.5
rs:WP_041677855	DNA topoisomerase I [Rhizobium tropici].	22.91	659	404	25	38	630	16	636	6e-17	95.5
rs:WP_016568498	DNA topoisomerase I [Pseudomonas syringae].	23.65	592	381	20	74	633	87	639	6e-17	95.5
rs:WP_002240958	DNA topoisomerase I [Neisseria meningitidis].	22.83	727	452	26	3	679	5	672	6e-17	95.5
rs:WP_024262211	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	6e-17	95.5
tr:A0A091RFY7_9GRUI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.91	563	364	18	36	564	26	552	6e-17	95.5
rs:WP_024515569	DNA topoisomerase I [Bradyrhizobium sp. Tv2a-2].	24.21	694	400	29	1	630	1	632	6e-17	95.5
rs:WP_047341422	DNA topoisomerase I [Enterococcus cecorum].	24.43	569	359	24	103	635	81	614	6e-17	95.1
rs:XP_009872449	PREDICTED: DNA topoisomerase 3-beta-1, partial [Apaloderma vittatum].	23.09	563	363	18	36	564	40	566	6e-17	95.5
rs:WP_046080869	DNA topoisomerase I [Escherichia fergusonii].	23.70	595	386	20	73	633	74	634	6e-17	95.5
rs:WP_024246437	DNA topoisomerase I [Escherichia coli].	22.91	646	407	26	73	673	74	673	6e-17	95.5
rs:WP_039095210	DNA topoisomerase I [Kirrobacter mercurialis].	22.84	705	416	29	1	646	1	636	6e-17	95.5
rs:WP_005229621	DNA topoisomerase I [Enterococcus casseliflavus].	25.35	572	350	24	103	635	81	614	6e-17	95.1
rs:WP_012143178	topoisomerase I [Shewanella sediminis].	22.99	622	369	22	65	631	76	642	6e-17	95.5
rs:WP_022327068	DNA topoisomerase [Prevotella sp. CAG:732].	23.31	622	390	17	3	602	5	561	6e-17	95.5
rs:WP_018876614	DNA topoisomerase I [Thioalkalivibrio sp. ALE31].	22.87	564	355	17	3	534	5	520	6e-17	95.5
rs:WP_018878614	DNA topoisomerase I [Thioalkalivibrio sp. ALE28].	23.19	565	352	18	3	534	5	520	6e-17	95.5
rs:WP_011919438	topoisomerase I [Shewanella putrefaciens].	23.54	480	298	16	186	631	197	641	6e-17	95.5
rs:WP_030004516	DNA topoisomerase I [Acholeplasma brassicae].	25.08	606	376	18	46	624	31	585	6e-17	95.1
rs:WP_003833325	MULTISPECIES: topoisomerase I [Citrobacter].	23.61	593	389	21	73	633	74	634	6e-17	95.5
tr:A0A0C9PQX4_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.86	591	365	18	94	639	74	624	6e-17	95.5
rs:WP_019508442	DNA topoisomerase I [Pleurocapsa sp. PCC 7319].	26.00	523	309	18	100	579	90	577	6e-17	95.5
tr:D3LS14_MICLU	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EFD49743.1};	31.44	229	140	6	1	221	1	220	6e-17	91.7
rs:WP_018999216	DNA topoisomerase I [Megamonas rupellensis].	22.67	600	368	20	90	636	69	625	6e-17	95.5
rs:XP_008573018	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Galeopterus variegatus].	22.10	629	404	21	3	585	5	593	6e-17	95.5
rs:WP_034452594	DNA topoisomerase I [Butyrivibrio sp. AE2032].	24.32	555	361	19	90	616	62	585	6e-17	95.1
tr:W1GKJ1_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.06	633	401	25	73	665	74	660	6e-17	95.1
rs:WP_008609910	topoisomerase I [Alishewanella aestuarii].	23.30	618	381	20	60	631	59	629	6e-17	95.5
rs:WP_042609034	DNA topoisomerase I [Pseudomonas fluorescens].	24.11	477	300	15	186	633	196	639	6e-17	95.5
rs:WP_005576194	topoisomerase I [Aggregatibacter actinomycetemcomitans].	23.94	472	307	12	187	633	196	640	6e-17	95.5
rs:XP_008393932	PREDICTED: uncharacterized protein LOC103456080 isoform X1 [Malus domestica].	23.40	624	371	27	64	618	333	918	6e-17	95.9
rs:WP_011697087	DNA topoisomerase I [Syntrophobacter fumaroxidans].	24.19	583	365	21	76	616	53	600	6e-17	95.5
rs:WP_014848241	DNA topoisomerase I [Zymomonas mobilis].	23.45	678	411	27	1	629	1	619	6e-17	95.9
rs:WP_038908015	DNA topoisomerase I [Dickeya zeae].	22.71	643	405	21	75	673	87	681	6e-17	95.5
rs:WP_020166935	MULTISPECIES: DNA topoisomerase I [Methylotenera].	23.64	664	384	26	2	614	3	594	6e-17	95.5
rs:WP_044638043	DNA topoisomerase I [Siansivirga zeaxanthinifaciens].	24.86	535	324	16	3	521	5	477	6e-17	95.5
rs:XP_001386841	DNA topoisomerase [Scheffersomyces stipitis CBS 6054].	22.15	623	406	19	3	580	4	592	6e-17	95.1
rs:WP_024900231	DNA topoisomerase I [Ochrobactrum rhizosphaerae].	22.97	688	415	26	1	629	1	632	6e-17	95.5
rs:WP_018966557	hypothetical protein, partial [Prevotella loescheii].	31.53	222	140	7	455	673	34	246	6e-17	91.7
rs:WP_024662799	DNA topoisomerase I [Pseudomonas syringae].	23.65	592	381	20	74	633	87	639	6e-17	95.5
rs:WP_024734480	DNA topoisomerase I [Clostridiales bacterium VE202-15].	23.02	569	355	19	90	616	67	594	7e-17	95.1
rs:WP_040000940	DNA topoisomerase I [Dickeya chrysanthemi].	22.55	643	406	21	75	673	81	675	7e-17	95.5
rs:WP_019723732	DNA topoisomerase I [Enterococcus mundtii].	25.83	573	346	25	103	635	81	614	7e-17	95.1
tr:T2J8Q9_CROWT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.91	573	351	18	84	610	61	594	7e-17	95.1
rs:WP_042207152	DNA topoisomerase I [Paenibacillus durus].	22.77	584	386	21	88	636	62	615	7e-17	95.1
rs:WP_001383172	DNA topoisomerase 1 [Escherichia coli].	23.66	596	385	22	73	633	74	634	7e-17	95.5
rs:WP_039064846	DNA topoisomerase I [Shigella flexneri].	23.63	601	379	24	73	633	74	634	7e-17	95.5
rs:WP_023145287	DNA topoisomerase I [Escherichia coli].	22.91	646	407	26	73	673	74	673	7e-17	95.5
rs:WP_046672863	DNA topoisomerase I [Sphingobacterium sp. Ag1].	24.76	525	330	15	76	578	53	534	7e-17	95.5
rs:XP_005281154	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Chrysemys picta bellii].	24.57	403	239	14	188	564	76	439	7e-17	95.1
rs:WP_039772798	DNA topoisomerase I [Pseudomonas fluorescens].	23.95	476	302	14	186	633	196	639	7e-17	95.5
tr:J6NN72_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EJX43865.1}; Flags: Fragment;	32.87	216	136	5	3	210	4	218	7e-17	90.9
rs:WP_029241462	DNA topoisomerase I [Pseudomonas viridiflava].	23.65	592	381	20	74	633	87	639	7e-17	95.5
rs:NP_269314	putative DNA topoisomerase I [Streptococcus pyogenes M1 GAS].	23.27	563	352	19	103	629	103	621	7e-17	95.1
rs:WP_022129322	DNA topoisomerase [Bacteroides sp. CAG:530].	23.21	616	387	20	3	604	5	548	7e-17	95.5
rs:WP_022736269	DNA topoisomerase I [Laceyella sacchari].	24.24	561	358	22	103	630	80	606	7e-17	95.1
rs:WP_005062053	topoisomerase I [Shigella flexneri].	23.63	601	379	24	73	633	74	634	7e-17	95.5
rs:WP_000513603	DNA topoisomerase I subunit omega, partial [Escherichia coli].	23.63	601	379	24	73	633	74	634	7e-17	95.1
rs:WP_012656741	DNA topoisomerase I [Macrococcus caseolyticus].	25.22	579	351	21	90	629	67	602	7e-17	95.1
rs:WP_032509134	DNA topoisomerase III, partial [Peptoclostridium difficile].	39.82	113	60	3	3	112	15	122	7e-17	88.6
rs:WP_025690981	DNA topoisomerase I [Paenibacillus zanthoxyli].	22.91	585	384	21	88	636	62	615	7e-17	95.1
rs:WP_017507300	DNA topoisomerase I [beta proteobacterium L13].	23.15	596	365	21	84	630	61	612	7e-17	95.1
rs:WP_013352247	DNA topoisomerase I [Bacillus amyloliquefaciens].	23.94	568	370	22	105	641	82	618	7e-17	95.1
rs:XP_005489017	PREDICTED: DNA topoisomerase 3-beta-1 [Zonotrichia albicollis].	22.91	563	364	18	36	564	83	609	7e-17	95.5
rs:WP_041789304	DNA topoisomerase I, partial [Rhodomicrobium vannielii].	22.90	642	393	23	55	630	27	632	7e-17	95.5
rs:WP_002821098	DNA topoisomerase I [Oenococcus oeni].	23.58	581	372	21	83	630	66	607	7e-17	95.1
rs:WP_002820441	DNA topoisomerase I [Oenococcus oeni].	23.58	581	372	21	83	630	66	607	7e-17	95.1
rs:WP_020396072	hypothetical protein [Thiothrix disciformis].	24.01	633	396	23	55	638	29	625	7e-17	95.5
rs:WP_034495748	MULTISPECIES: DNA topoisomerase I [Rhizobium/Agrobacterium group].	22.41	705	403	29	1	630	1	636	7e-17	95.5
rs:WP_041014252	MULTISPECIES: DNA topoisomerase I [Pseudomonas stutzeri group].	23.43	478	300	12	187	633	194	636	7e-17	95.5
rs:WP_033792958	hypothetical protein, partial [Helicobacter pylori].	25.00	652	393	27	6	611	1	602	7e-17	95.1
rs:WP_032739665	DNA topoisomerase I, partial [Klebsiella pneumoniae].	23.54	480	299	15	187	633	73	517	7e-17	95.1
rs:WP_002237530	DNA topoisomerase I [Neisseria meningitidis].	22.83	727	452	26	3	679	5	672	7e-17	95.1
tr:W8FAX8_RHIRD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.90	636	368	26	70	630	1	595	7e-17	95.5
rs:WP_027673005	DNA topoisomerase I [Agrobacterium larrymoorei].	23.15	674	396	27	32	630	10	636	7e-17	95.5
rs:WP_047274029	DNA topoisomerase I [Pseudomonas fluorescens].	23.95	476	302	14	186	633	196	639	7e-17	95.5
rs:WP_007193248	DNA topoisomerase I [Thiocapsa marina].	23.46	601	381	23	76	630	51	618	7e-17	95.1
rs:WP_043104337	DNA topoisomerase I [Xanthomonadaceae bacterium 3.5X].	22.18	568	357	15	3	536	5	521	7e-17	95.5
rs:WP_016500743	DNA topoisomerase I [Pseudomonas putida].	23.65	482	296	14	186	633	195	638	7e-17	95.5
rs:WP_008705704	MULTISPECIES: DNA topoisomerase I [Clostridiales].	24.23	549	340	21	103	616	80	587	7e-17	95.1
rs:WP_025714303	DNA topoisomerase I [Klebsiella sp. 10982].	22.90	607	385	19	60	633	78	634	7e-17	95.5
rs:WP_034313673	DNA topoisomerase I [Bacillus simplex].	22.86	560	375	20	105	635	82	613	7e-17	95.1
rs:WP_017051947	topoisomerase I [Vibrio genomosp. F6].	23.71	603	368	19	75	633	85	639	7e-17	95.5
tr:A0A0C6FVI5_STRPY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.27	563	352	19	103	629	103	621	7e-17	95.1
rs:WP_025880938	DNA topoisomerase I [Prevotella baroniae].	23.47	622	380	20	3	604	5	550	7e-17	95.1
rs:WP_011928996	DNA topoisomerase I [Dehalococcoides mccartyi].	24.44	675	390	26	2	624	4	610	7e-17	95.1
rs:WP_002838175	DNA topoisomerase I [Finegoldia magna].	24.07	648	392	27	2	616	5	585	7e-17	95.1
rs:WP_021250287	DNA topoisomerase I [Thauera terpenica].	23.56	573	362	19	90	631	64	591	7e-17	95.1
rs:XP_003061949	predicted protein [Micromonas pusilla CCMP1545].	21.45	606	399	21	3	564	5	577	7e-17	95.5
rs:WP_012663553	reverse gyrase [Nautilia profundicola].	27.45	623	313	28	3	586	547	1069	7e-17	95.5
rs:WP_043106819	DNA topoisomerase I [endosymbiont of unidentified scaly snail isolate Monju].	22.44	673	422	25	1	630	1	616	7e-17	95.1
rs:WP_045789265	DNA topoisomerase I [Aeromonas hydrophila].	24.26	606	362	22	75	633	82	637	7e-17	95.5
tr:K1RF63_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC44248.1};	36.59	123	62	4	1	116	3	116	7e-17	88.6
rs:WP_047293077	DNA topoisomerase I [Pseudomonas fluorescens].	23.95	476	302	14	186	633	196	639	7e-17	95.5
tr:F7JP29_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGN36663.1};	32.55	212	128	7	70	274	1	204	7e-17	90.9
rs:WP_000513587	topoisomerase I [Salmonella enterica].	23.18	617	376	21	73	633	74	648	7e-17	95.5
rs:WP_003703765	DNA topoisomerase I [Lactobacillus salivarius].	22.57	576	369	21	90	629	82	616	7e-17	95.1
rs:XP_001991334	GH12112 [Drosophila grimshawi].	22.46	610	399	20	3	573	5	579	7e-17	95.5
rs:WP_003438266	DNA topoisomerase I [Peptoclostridium difficile].	24.79	718	415	31	3	675	5	642	7e-17	95.1
rs:WP_011912884	topoisomerase I [Pseudomonas stutzeri].	23.48	477	301	12	187	633	194	636	7e-17	95.5
rs:WP_022160764	DNA topoisomerase [Odoribacter splanchnicus CAG:14].	24.91	538	319	19	3	520	5	477	7e-17	95.1
rs:WP_013629763	DNA topoisomerase I [Planctomyces brasiliensis].	23.90	523	332	15	77	560	74	569	7e-17	95.5
tr:A0A0D5LX21_ACIBA	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:AJY48480.1};	25.36	485	318	14	67	537	51	505	7e-17	95.1
rs:WP_042563873	DNA topoisomerase I [Flavobacterium sp. MEB061].	25.05	535	323	18	3	521	5	477	7e-17	95.5
tr:A0A015P4D9_BACFG	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EXY29744.1}; Flags: Fragment;	39.84	123	72	2	467	588	67	188	7e-17	92.0
rs:WP_028693758	DNA topoisomerase I [Pseudomonas cremoricolorata].	24.11	477	300	15	186	633	195	638	7e-17	95.5
rs:WP_044135611	DNA topoisomerase III, partial [Bacteroides fragilis].	39.84	123	72	2	467	588	73	194	7e-17	92.0
rs:WP_037019380	DNA topoisomerase I [Pseudomonas lutea].	22.29	646	417	21	77	682	62	662	7e-17	95.1
rs:WP_036909333	hypothetical protein [Prevotella timonensis].	32.24	183	122	2	130	311	51	232	7e-17	91.3
rs:WP_008954815	DNA topoisomerase I [Pseudogulbenkiania ferrooxidans].	23.08	663	420	24	3	630	5	612	7e-17	95.1
tr:U4PWA0_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.41	705	403	29	1	630	1	636	7e-17	95.5
rs:WP_039261035	DNA topoisomerase I [Clostridium tetani].	26.02	561	340	19	90	616	67	586	7e-17	95.1
rs:WP_032280486	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	7e-17	95.5
rs:WP_016492045	DNA topoisomerase I [Pseudomonas resinovorans].	23.00	474	309	12	186	633	195	638	7e-17	95.5
rs:WP_032465637	DNA topoisomerase, partial [Streptococcus pyogenes].	39.17	120	61	4	3	117	41	153	7e-17	89.4
rs:WP_045046682	DNA topoisomerase I [Rouxiella chamberiensis].	24.14	609	355	22	76	633	82	634	7e-17	95.1
rs:WP_001607265	DNA topoisomerase 1 [Escherichia coli].	23.75	602	377	25	73	633	74	634	7e-17	95.1
sp:TOP1P_XYLFA	RecName: Full=DNA topoisomerase I, plasmid {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.52	473	302	13	90	539	64	504	7e-17	94.7
rs:WP_033910715	DNA topoisomerase I [Neisseria gonorrhoeae].	22.56	727	454	26	3	679	5	672	7e-17	95.1
rs:WP_022502718	DNA topoisomerase [Eubacterium sp. CAG:76].	24.56	570	353	21	83	616	60	588	8e-17	95.1
rs:WP_039284392	DNA topoisomerase I [Novosphingobium malaysiense].	22.01	677	418	23	1	629	1	615	8e-17	95.1
rs:WP_013961209	DNA topoisomerase I [Roseobacter litoralis].	22.17	699	399	27	1	629	1	624	8e-17	95.1
rs:WP_002256289	DNA topoisomerase I [Neisseria meningitidis].	22.83	727	452	26	3	679	5	672	8e-17	95.1
rs:WP_002221835	DNA topoisomerase I [Neisseria meningitidis].	22.97	727	451	26	3	679	5	672	8e-17	95.1
rs:WP_002216226	DNA topoisomerase I [Neisseria meningitidis].	22.83	727	452	26	3	679	5	672	8e-17	95.1
rs:WP_001560478	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	8e-17	95.1
rs:WP_027097528	DNA topoisomerase I [Clostridium paraputrificum].	24.51	567	355	17	83	616	60	586	8e-17	95.1
rs:WP_034945873	DNA topoisomerase I [Gilliamella apicola].	22.80	601	378	16	74	633	82	637	8e-17	95.1
rs:WP_011065946	DNA topoisomerase I [Oceanobacillus iheyensis].	24.04	574	352	21	105	635	82	614	8e-17	95.1
rs:WP_024689275	DNA topoisomerase I [Pseudomonas syringae].	23.65	592	381	20	74	633	87	639	8e-17	95.1
rs:WP_002224383	DNA topoisomerase I [Neisseria meningitidis].	22.83	727	452	26	3	679	5	672	8e-17	95.1
rs:XP_006993093	PREDICTED: DNA topoisomerase 3-beta-1 [Peromyscus maniculatus bairdii].	22.89	629	399	24	3	585	5	593	8e-17	95.1
rs:WP_032460103	DNA topoisomerase I [Streptococcus pyogenes].	23.45	563	351	19	103	629	103	621	8e-17	95.1
rs:WP_016351565	DNA topoisomerase I subunit omega [Aeromonas hydrophila].	24.26	606	362	22	75	633	82	637	8e-17	95.1
rs:WP_025579645	DNA topoisomerase I [Blautia wexlerae].	24.23	549	340	21	103	616	80	587	8e-17	95.1
rs:WP_032297743	DNA topoisomerase I [Escherichia coli].	24.01	604	373	25	73	633	74	634	8e-17	95.1
rs:WP_039358543	DNA topoisomerase I [Pectobacterium carotovorum].	24.33	600	369	22	74	633	81	635	8e-17	95.1
rs:WP_036069502	DNA topoisomerase I [Listeria rocourtiae].	23.04	560	374	20	105	635	82	613	8e-17	95.1
tr:D1Y390_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.22	657	401	23	3	615	74	664	8e-17	95.1
rs:WP_031943396	DNA topoisomerase I [uncultured bacterium].	24.03	595	370	18	82	636	63	615	8e-17	94.7
tr:R0AG44_CLOBU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ENZ31102.1};	33.89	180	111	5	497	673	6	180	8e-17	90.9
rs:WP_035594534	DNA topoisomerase I [Hyphomonas polymorpha].	23.75	682	411	27	1	629	1	626	8e-17	95.1
rs:WP_012162550	DNA topoisomerase I [Acaryochloris marina].	23.47	639	378	21	3	584	4	588	8e-17	95.1
rs:WP_020208865	hypothetical protein [Gilvimarinus chinensis].	22.92	554	346	18	1	533	1	494	8e-17	94.7
rs:WP_001337939	DNA topoisomerase 1 [Escherichia coli].	22.91	646	407	26	73	673	74	673	8e-17	95.1
rs:WP_027467839	DNA topoisomerase I [Deefgea rivuli].	23.87	599	382	19	74	630	51	617	8e-17	95.1
rs:WP_016288835	DNA topoisomerase I [Lachnospiraceae bacterium 3-1].	24.56	562	350	20	90	616	67	589	8e-17	94.7
rs:WP_044253769	DNA topoisomerase I [Isosphaera pallida].	24.44	581	360	21	90	631	63	603	8e-17	95.1
rs:NP_001193635	DNA topoisomerase 3-beta-1 [Bos taurus].	22.42	629	402	22	3	585	5	593	8e-17	95.1
tr:C0D9F9_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.02	569	355	19	90	616	73	600	8e-17	95.1
rs:WP_044934103	DNA topoisomerase I [Pseudobutyrivibrio sp. LB2011].	23.62	614	391	21	36	616	22	590	8e-17	94.7
rs:WP_005091745	topoisomerase I [Shigella flexneri].	23.63	601	379	24	73	633	74	634	8e-17	95.1
rs:WP_024094293	DNA topoisomerase 1 [Paenibacillus larvae].	24.13	576	355	24	103	636	80	615	8e-17	94.7
rs:WP_005379878	DNA topoisomerase I [Veillonella atypica].	24.26	577	349	22	95	629	135	665	8e-17	95.1
rs:WP_029418511	DNA topoisomerase I [Bacillus sonorensis].	23.71	561	369	21	105	635	82	613	8e-17	94.7
rs:WP_033550377	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	8e-17	95.1
rs:WP_024232160	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	8e-17	95.1
rs:WP_040473085	topoisomerase I, partial [Lactobacillus coryniformis].	25.34	221	159	3	363	581	1	217	8e-17	92.0
rs:WP_039792923	DNA topoisomerase I, partial [Pseudomonas agarici].	23.00	474	307	13	187	633	63	505	8e-17	95.1
tr:A0A0D6QN89_9DELT	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:GAO04267.1};	23.53	629	391	23	76	646	97	693	8e-17	95.1
rs:WP_011816400	DNA topoisomerase I [Yersinia enterocolitica].	23.52	608	364	19	74	633	86	640	8e-17	95.1
rs:WP_039066768	DNA topoisomerase I [Staphylococcus xylosus].	24.18	550	367	18	103	629	80	602	8e-17	94.7
rs:WP_020359163	DNA topoisomerase I [Chlamydia psittaci].	24.65	572	341	25	3	534	5	526	8e-17	95.1
rs:WP_021375035	DNA topoisomerase I [Peptoclostridium difficile].	24.79	718	415	31	3	675	5	642	8e-17	94.7
rs:WP_005068394	topoisomerase I [Shigella flexneri].	23.63	601	379	24	73	633	74	634	8e-17	95.1
rs:WP_017359093	DNA topoisomerase I [Bacillus pumilus].	24.27	511	333	20	154	636	130	614	8e-17	94.7
rs:WP_045367392	DNA topoisomerase I [Methyloceanibacter caenitepidi].	23.44	687	413	26	1	630	1	631	8e-17	95.1
tr:K1UDR3_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC69636.1}; Flags: Fragment;	26.14	264	182	6	418	676	14	269	8e-17	91.7
rs:WP_011475885	DNA topoisomerase I [Lactobacillus salivarius].	22.57	576	369	21	90	629	82	616	8e-17	94.7
rs:WP_039874304	DNA topoisomerase I [Paenibacillus sp. FSL R7-0273].	24.03	566	368	20	103	636	80	615	8e-17	94.7
rs:WP_028865557	DNA topoisomerase I [Psychromonas aquimarina].	24.71	599	369	21	74	633	88	643	8e-17	95.1
rs:WP_006233149	topoisomerase I [Photobacterium profundum].	24.59	606	355	19	76	633	88	639	8e-17	95.1
rs:WP_001361672	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	8e-17	95.1
rs:WP_025993435	DNA topoisomerase I [Pseudomonas viridiflava].	23.65	592	381	20	74	633	87	639	8e-17	95.1
rs:WP_002220143	DNA topoisomerase I [Neisseria meningitidis].	22.83	727	452	26	3	679	5	672	8e-17	95.1
rs:WP_018075375	DNA topoisomerase I [Novosphingobium nitrogenifigens].	20.95	673	432	22	1	629	1	617	8e-17	95.1
rs:WP_028131801	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	8e-17	95.1
rs:WP_001360019	topoisomerase I [Escherichia coli].	23.67	600	380	23	73	633	74	634	8e-17	95.1
tr:A0A0D2D6H0_9EURO	SubName: Full=Strain CBS 83496 unplaced genomic scaffold supercont1.2, whole genome shotgun sequence {ECO:0000313|EMBL:KIW31309.1};	23.06	633	400	23	3	584	7	603	8e-17	94.7
rs:WP_031596742	DNA topoisomerase I, partial [Ferrovum myxofaciens].	22.27	696	408	29	2	639	4	624	8e-17	95.1
rs:WP_015900135	DNA topoisomerase I [Staphylococcus carnosus].	23.62	597	383	20	90	649	67	627	8e-17	94.7
rs:WP_033552514	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	8e-17	95.1
rs:WP_016234290	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	8e-17	95.1
tr:Q6N2B4_RHOPA	SubName: Full=Complete genome; segment 14/16 {ECO:0000313|EMBL:CAE29577.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CAE29577.1};	24.76	420	282	10	272	657	87	506	8e-17	94.7
rs:XP_002011041	GI16324 [Drosophila mojavensis].	25.00	408	262	12	188	585	210	583	8e-17	95.1
tr:U2DPA3_9CLOT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ERI81541.1};	32.12	193	123	4	497	683	14	204	8e-17	90.9
rs:WP_012633970	DNA topoisomerase I [Anaeromyxobacter dehalogenans].	24.01	633	383	25	76	646	97	693	8e-17	95.1
rs:WP_003106911	DNA topoisomerase I [Streptococcus parauberis].	22.97	579	374	22	83	629	84	622	8e-17	94.7
rs:WP_039295145	MULTISPECIES: DNA topoisomerase I [Paenibacillus].	23.46	584	382	20	88	636	62	615	8e-17	94.7
rs:WP_032169931	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	8e-17	95.1
rs:WP_042308078	DNA topoisomerase I [Citrobacter werkmanii].	23.46	601	380	22	73	633	74	634	8e-17	95.1
rs:WP_021516023	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	8e-17	95.1
rs:WP_021708677	DNA topoisomerase I [Vibrio azureus].	23.63	601	375	19	73	633	84	640	8e-17	95.1
rs:WP_020159280	DNA topoisomerase I [Methylobacter marinus].	25.67	409	250	15	157	534	136	521	8e-17	95.1
rs:WP_005191581	topoisomerase I [Yersinia intermedia].	24.00	600	371	21	74	633	86	640	8e-17	95.1
tr:C9X1P3_NEIM8	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.97	727	451	26	3	679	5	672	8e-17	95.1
rs:WP_002225938	DNA topoisomerase I [Neisseria meningitidis].	22.97	727	451	26	3	679	5	672	8e-17	95.1
rs:WP_023409680	DNA topoisomerase I [uncultured Thiohalocapsa sp. PB-PSB1].	22.64	711	406	28	1	618	1	660	8e-17	95.1
rs:WP_001682840	DNA topoisomerase 1 [Escherichia coli].	22.91	646	407	26	73	673	74	673	8e-17	95.1
rs:WP_005023339	topoisomerase I [Shigella dysenteriae].	23.79	601	378	24	73	633	74	634	8e-17	95.1
rs:WP_021380353	DNA topoisomerase I [Peptoclostridium difficile].	24.79	718	415	31	3	675	5	642	8e-17	94.7
rs:WP_015449009	MULTISPECIES: DNA topoisomerase I [Rhodanobacter].	22.30	610	396	16	77	638	54	633	8e-17	95.1
tr:W1B3B9_KLEPN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.14	631	399	25	83	673	5	589	8e-17	95.1
tr:R0L3G6_ANAPL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.09	563	363	18	36	564	33	559	9e-17	95.1
rs:WP_017969400	DNA topoisomerase I [alpha proteobacterium SCGC AAA280-P20].	23.95	643	376	26	1	597	1	576	9e-17	95.1
rs:WP_043304444	DNA topoisomerase I [Pseudomonas viridiflava].	23.65	592	381	20	74	633	87	639	9e-17	95.1
rs:WP_031552912	DNA topoisomerase I [Oribacterium sp. FC2011].	23.38	556	372	15	83	616	60	583	9e-17	94.7
rs:WP_038324611	DNA topoisomerase I [bacterium MS4].	23.18	647	406	20	2	616	3	590	9e-17	94.7
rs:WP_006712555	topoisomerase I [Vibrio ichthyoenteri].	23.32	596	379	19	75	633	85	639	9e-17	95.1
rs:WP_022296446	MULTISPECIES: DNA topoisomerase [Escherichia].	23.62	597	384	22	73	633	74	634	9e-17	95.1
rs:WP_007953057	MULTISPECIES: topoisomerase I [Pseudomonas].	24.11	477	300	15	186	633	196	639	9e-17	95.1
tr:C2BCN8_9FIRM	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EEI87330.1};	35.88	131	76	3	1	128	1	126	9e-17	89.0
tr:E3HZ27_RHOVT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.90	642	393	23	55	630	27	632	9e-17	95.1
rs:WP_023908201	DNA topoisomerase I [Xylella fastidiosa].	24.52	473	302	13	90	539	64	504	9e-17	94.7
rs:WP_043156147	DNA topoisomerase I [Pseudomonas aeruginosa].	22.37	599	380	19	74	633	85	637	9e-17	95.1
rs:WP_046514712	DNA topoisomerase I [Bacillus sp. SA1-12].	23.04	560	374	20	105	635	82	613	9e-17	94.7
rs:WP_036248415	DNA topoisomerase I [Methylobacter sp. BBA5.1].	25.67	409	250	15	157	534	136	521	9e-17	95.1
rs:XP_002036798	GM12581 [Drosophila sechellia].	24.30	461	302	15	188	630	257	688	9e-17	95.1
rs:XP_005007385	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Cavia porcellus].	22.73	629	400	21	3	585	5	593	9e-17	95.1
rs:WP_020833479	DNA topoisomerase I [Streptococcus pyogenes].	23.21	560	356	18	103	629	103	621	9e-17	94.7
rs:WP_025044027	DNA topoisomerase I [Sulfitobacter sp. MM-124].	23.19	565	345	20	1	534	1	507	9e-17	95.1
rs:WP_001362355	topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	9e-17	95.1
rs:WP_001518579	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	9e-17	95.1
rs:WP_010658870	DNA topoisomerase I [Ochrobactrum anthropi].	23.62	707	387	30	1	629	1	632	9e-17	95.1
rs:WP_021422224	DNA topoisomerase I [Peptoclostridium difficile].	24.79	718	415	31	3	675	5	642	9e-17	94.7
rs:WP_003285574	topoisomerase I [Pseudomonas stutzeri].	23.75	480	296	14	187	633	194	636	9e-17	95.1
rs:WP_041699504	DNA topoisomerase I, partial [Pseudanabaena sp. PCC 7367].	24.57	639	352	23	3	577	4	576	9e-17	95.1
rs:WP_036101696	DNA topoisomerase I [Listeria riparia].	23.54	565	369	22	103	635	80	613	9e-17	94.7
rs:WP_044806905	DNA topoisomerase I, partial [Escherichia coli].	23.63	601	379	24	73	633	74	634	9e-17	94.7
rs:WP_036688567	MULTISPECIES: DNA topoisomerase I [Paenibacillus].	23.85	587	376	23	88	636	62	615	9e-17	94.7
rs:WP_029273334	DNA topoisomerase I [Flavobacterium sp. KJJ].	24.77	533	327	18	3	521	5	477	9e-17	95.1
rs:WP_040089153	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	9e-17	95.1
rs:WP_005049701	topoisomerase I [Shigella flexneri].	23.63	601	379	24	73	633	74	634	9e-17	95.1
rs:WP_001304419	MULTISPECIES: DNA topoisomerase I [Escherichia].	23.63	601	379	24	73	633	74	634	9e-17	95.1
rs:WP_040054012	DNA topoisomerase I, partial [Candidatus Arthromitus sp. SFB-4].	25.89	506	315	15	103	580	80	553	9e-17	94.4
rs:WP_017414512	hypothetical protein [Clostridium tunisiense].	24.65	568	341	17	90	616	67	588	9e-17	94.7
rs:WP_006468939	MULTISPECIES: DNA topoisomerase I [Ochrobactrum].	24.02	691	404	30	1	629	1	632	9e-17	95.1
rs:WP_014915357	topoisomerase I [Pectobacterium carotovorum].	24.33	600	369	22	74	633	81	635	9e-17	95.1
rs:WP_016688293	DNA topoisomerase I [Neisseria sicca].	22.69	670	424	23	70	679	37	672	9e-17	94.7
rs:WP_015060283	DNA topoisomerase I [uncultured bacterium HHV35].	25.15	485	319	14	67	537	51	505	9e-17	94.7
tr:C2EF62_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.57	576	369	21	90	629	94	628	9e-17	94.7
rs:WP_044864065	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	9e-17	95.1
rs:WP_001591966	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	9e-17	95.1
rs:WP_001583462	DNA topoisomerase 1 [Escherichia coli].	23.79	601	378	24	73	633	74	634	9e-17	95.1
tr:K1Y6Q8_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.61	648	399	21	1	616	1	584	9e-17	95.1
rs:WP_032121749	DNA topoisomerase I [Clostridium sp. LF2].	26.69	577	316	20	90	616	67	586	9e-17	94.7
rs:WP_029147941	DNA topoisomerase I [Methylophilus sp. 5].	22.87	669	385	26	2	614	3	596	9e-17	95.1
rs:WP_009175240	DNA topoisomerase I [Neisseria sp. oral taxon 014].	23.40	671	418	25	70	679	37	672	9e-17	94.7
rs:WP_019841512	topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	9e-17	95.1
rs:WP_000513601	topoisomerase I [Escherichia fergusonii].	23.67	600	380	23	73	633	74	634	9e-17	95.1
tr:A0A091G822_9AVES	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.09	563	363	18	36	564	26	552	9e-17	95.1
rs:WP_031382963	DNA topoisomerase I [Halomonas zincidurans].	24.59	484	288	17	186	633	201	643	9e-17	95.1
rs:WP_022195275	DNA topoisomerase [Azospirillum sp. CAG:239].	23.40	688	402	28	1	629	1	622	9e-17	95.1
rs:WP_001538694	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	9e-17	95.1
rs:WP_007949671	topoisomerase I [Pseudomonas sp. GM24].	24.11	477	300	15	186	633	196	639	9e-17	95.1
rs:WP_022796267	DNA topoisomerase I [Bavariicoccus seileri].	23.20	582	360	21	90	629	68	604	9e-17	94.7
tr:K8AMF9_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.93	606	371	22	73	633	88	648	9e-17	95.1
rs:WP_042294584	DNA topoisomerase I [Candidatus Arthromitus sp. SFB-mouse-NL].	25.14	541	339	17	103	614	80	583	9e-17	94.7
rs:WP_001684861	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	9e-17	95.1
rs:WP_011378684	DNA topoisomerase I [Shigella dysenteriae].	23.79	601	378	24	73	633	74	634	9e-17	95.1
rs:WP_042101137	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	9e-17	95.1
rs:WP_042441694	DNA topoisomerase III, partial [Rhodopseudomonas palustris].	24.75	400	271	9	288	657	1	400	9e-17	94.4
tr:A0A091PQ62_LEPDC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.09	563	363	18	36	564	26	552	9e-17	95.1
rs:WP_004843019	DNA topoisomerase I [[Ruminococcus] gnavus].	24.46	560	353	20	90	616	67	589	9e-17	94.7
rs:WP_001339670	MULTISPECIES: topoisomerase I [Enterobacteriaceae].	23.63	601	379	24	73	633	74	634	9e-17	95.1
tr:C3V9X4_9PSED	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.28	597	377	20	74	633	85	637	9e-17	95.1
rs:WP_042108431	DNA topoisomerase I, partial [Escherichia coli].	23.63	601	379	24	73	633	74	634	9e-17	94.7
rs:WP_046426265	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	9e-17	95.1
tr:W8JMV0_9CHLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.65	572	341	25	3	534	8	529	9e-17	95.1
rs:WP_026464733	DNA topoisomerase I [Adhaeribacter aquaticus].	22.98	631	378	22	3	602	5	558	9e-17	94.7
rs:WP_015017017	DNA topoisomerase I [Streptococcus dysgalactiae].	22.98	583	369	20	83	629	93	631	9e-17	94.7
rs:WP_012311849	DNA topoisomerase I [Escherichia coli].	23.66	596	385	22	73	633	74	634	9e-17	95.1
rs:WP_047250598	DNA topoisomerase I [Thioalkalivibrio versutus].	23.55	569	345	20	3	534	5	520	9e-17	95.1
rs:WP_020301296	DNA topoisomerase I [Pseudomonas sp. CF150].	23.25	486	308	15	77	535	62	509	9e-17	94.0
tr:A0A0D2I1P8_9EURO	SubName: Full=Rhinocladiella mackenziei CBS 650.93 unplaced genomic scaffold supercont1.11, whole genome shotgun sequence {ECO:0000313|EMBL:KIW99668.1};	23.91	640	387	28	3	584	7	604	9e-17	94.4
rs:WP_021583487	topoisomerase repeat protein, partial [Prevotella pleuritidis].	31.96	219	138	7	458	673	1	211	9e-17	90.9
rs:XP_002106294	GD16199 [Drosophila simulans].	24.80	379	250	10	188	557	157	509	9e-17	94.7
rs:WP_036152236	DNA topoisomerase I [Lysinibacillus odysseyi].	23.88	557	364	17	103	629	80	606	9e-17	94.7
rs:WP_001366271	topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	9e-17	95.1
rs:WP_001506205	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	9e-17	95.1
rs:WP_018939267	DNA topoisomerase I [Thioalkalivibrio sp. AKL11].	23.37	569	346	20	3	534	5	520	9e-17	95.1
rs:XP_005907409	PREDICTED: DNA topoisomerase 3-beta-1 [Bos mutus].	22.58	629	401	22	3	585	5	593	9e-17	95.1
rs:WP_035623284	DNA topoisomerase I [Flavobacterium hydatis].	25.52	533	323	21	3	521	5	477	9e-17	95.1
rs:WP_040035700	DNA topoisomerase I [Pectobacterium carotovorum].	24.33	600	369	22	74	633	81	635	9e-17	95.1
tr:A0A090NCS4_SHIDY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.79	601	378	24	73	633	88	648	9e-17	95.1
rs:WP_018780929	MULTISPECIES: DNA topoisomerase I [Bacillus].	23.21	560	373	20	105	635	82	613	9e-17	94.7
rs:WP_010719464	MULTISPECIES: DNA topoisomerase I [Enterococcus].	26.00	573	345	24	103	635	81	614	9e-17	94.7
rs:WP_018193230	MULTISPECIES: hypothetical protein [unclassified Thaumarchaeota (miscellaneous)].	21.30	601	413	17	3	587	5	561	9e-17	94.4
tr:K1S3C4_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC55112.1}; Flags: Fragment;	32.43	222	134	7	157	365	7	225	9e-17	91.7
rs:WP_033102341	DNA topoisomerase I [Thermoactinomyces daqus].	23.33	570	352	23	103	630	80	606	9e-17	94.7
rs:XP_003862289	DNA topoisomerase III, putative [Leishmania donovani].	21.71	608	397	18	3	571	6	573	9e-17	95.1
rs:WP_006286687	topoisomerase IA [Paenibacillus popilliae].	24.25	569	363	21	103	636	80	615	9e-17	94.7
tr:S7VT95_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.80	446	260	15	98	521	75	480	9e-17	94.7
rs:WP_021236287	DNA topoisomerase I [Novosphingobium lindaniclasticum].	21.98	678	417	24	1	629	1	615	1e-16	95.1
rs:WP_038433403	DNA topoisomerase I [Streptococcus pyogenes].	23.09	563	353	19	103	629	103	621	1e-16	94.7
rs:WP_009880713	DNA topoisomerase I [Streptococcus pyogenes].	23.27	563	352	19	103	629	103	621	1e-16	94.7
rs:WP_032352450	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	95.1
rs:WP_045177202	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	95.1
rs:WP_001487192	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	95.1
rs:WP_041705892	DNA topoisomerase I, partial [Mageeibacillus indolicus].	23.54	667	408	24	3	629	5	609	1e-16	94.7
rs:WP_005762130	topoisomerase I [Pasteurella dagmatis].	23.75	598	375	20	74	633	86	640	1e-16	95.1
rs:WP_038414203	DNA topoisomerase I [Pseudomonas cremoricolorata].	24.11	477	300	15	186	633	195	638	1e-16	95.1
rs:WP_001295576	MULTISPECIES: DNA topoisomerase I [Enterobacteriaceae].	23.63	601	379	24	73	633	74	634	1e-16	95.1
rs:WP_003105989	DNA topoisomerase I [Streptococcus parauberis].	22.97	579	374	22	83	629	84	622	1e-16	94.7
tr:A0A090QNN5_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.51	587	385	16	76	633	88	639	1e-16	95.1
rs:WP_001691736	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	95.1
rs:WP_047085249	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	95.1
rs:WP_018951810	DNA topoisomerase I [Thioalkalivibrio sp. AKL12].	23.55	569	345	20	3	534	5	520	1e-16	94.7
tr:T0U0C6_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.04	233	149	5	299	519	2	225	1e-16	90.5
rs:XP_004922832	PREDICTED: DNA topoisomerase 3-beta-1 [Bombyx mori].	23.32	476	310	15	188	639	211	655	1e-16	94.7
tr:A0A0A2RI15_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.63	601	379	24	73	633	74	634	1e-16	94.7
rs:WP_016525066	DNA topoisomerase I [Treponema maltophilum].	25.05	495	313	17	163	629	144	608	1e-16	94.7
rs:WP_025390203	DNA topoisomerase I [Pseudomonas syringae].	23.65	592	381	20	74	633	87	639	1e-16	94.7
rs:WP_045152100	DNA topoisomerase I [Escherichia coli].	23.54	599	379	24	73	633	74	631	1e-16	94.7
rs:WP_038500965	DNA topoisomerase I [Chlamydia avium].	24.65	572	341	25	3	534	5	526	1e-16	94.7
rs:WP_039025800	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	94.7
rs:WP_017246024	topoisomerase I [Pseudomonas stutzeri].	23.48	477	301	12	187	633	194	636	1e-16	94.7
rs:WP_021411029	DNA topoisomerase I [Peptoclostridium difficile].	24.79	718	415	31	3	675	5	642	1e-16	94.7
tr:A0A0A0F9H1_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.63	601	379	24	73	633	88	648	1e-16	94.7
rs:WP_002242228	DNA topoisomerase I [Neisseria meningitidis].	22.83	727	452	26	3	679	5	672	1e-16	94.7
rs:WP_020240018	topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	94.7
rs:WP_001718167	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	94.7
rs:WP_004243046	topoisomerase I [Proteus mirabilis].	21.80	656	389	21	77	673	83	673	1e-16	94.7
rs:WP_001335024	topoisomerase I [Escherichia coli].	23.67	600	380	23	73	633	74	634	1e-16	94.7
gpu:CP011403_722	DNA topoisomerase I [Lactobacillus salivarius str. Ren]	22.57	576	369	21	90	629	40	574	1e-16	94.4
tr:K2F0M1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.26	675	414	24	1	629	1	617	1e-16	94.7
rs:WP_034841315	DNA topoisomerase I [Endozoicomonas numazuensis].	23.39	607	385	19	65	633	80	644	1e-16	94.7
rs:WP_001573409	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	94.7
rs:WP_027638117	DNA topoisomerase I [Clostridium cadaveris].	25.87	576	336	21	83	616	60	586	1e-16	94.7
tr:K9SJI8_9CYAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.57	639	352	23	3	577	4	576	1e-16	95.1
rs:WP_042832014	DNA topoisomerase III, partial [Xanthomonas citri].	29.24	171	114	3	1	170	1	165	1e-16	89.4
tr:A0A076LKY0_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	30.09	339	199	15	3	322	4	323	1e-16	95.1
rs:WP_009416627	DNA topoisomerase I [Capnocytophaga sp. oral taxon 332].	25.66	534	321	19	3	521	5	477	1e-16	94.7
rs:WP_007039086	DNA topoisomerase I [Thiorhodococcus drewsii].	24.78	577	333	25	1	534	1	519	1e-16	94.7
rs:WP_042784671	DNA topoisomerase I [Serratia sp. SCBI].	24.01	608	361	22	74	633	80	634	1e-16	94.7
rs:WP_004248126	topoisomerase I [Proteus mirabilis].	21.80	656	389	21	77	673	83	673	1e-16	94.7
rs:WP_016989276	DNA topoisomerase I [Flavobacterium sp. ACAM 123].	25.00	536	322	21	3	521	5	477	1e-16	94.7
rs:WP_022619737	DNA topoisomerase I [Peptoclostridium difficile].	24.67	677	394	28	3	634	5	610	1e-16	94.7
rs:WP_040534196	DNA topoisomerase I [Lactobacillus shenzhenensis].	24.19	583	368	21	90	635	67	612	1e-16	94.7
rs:WP_017906684	topoisomerase I [Pseudomonas fuscovaginae].	23.00	474	309	12	186	633	196	639	1e-16	94.7
rs:WP_001485714	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	94.7
rs:WP_047370484	DNA topoisomerase I [Kluyvera intermedia].	24.21	603	373	22	73	633	74	634	1e-16	94.7
rs:WP_019052099	DNA topoisomerase I [Sphingobium xenophagum].	21.73	672	425	23	1	629	1	614	1e-16	94.7
rs:WP_044323044	DNA topoisomerase I [Pseudomonas amygdali].	23.48	592	382	20	74	633	87	639	1e-16	94.7
rs:WP_002224768	DNA topoisomerase I [Neisseria meningitidis].	22.83	727	452	26	3	679	5	672	1e-16	94.7
rs:WP_033747866	hypothetical protein, partial [Helicobacter pylori].	24.69	652	395	26	6	611	1	602	1e-16	94.7
rs:WP_042029466	DNA topoisomerase 1 [Escherichia coli].	23.66	596	385	22	73	633	74	634	1e-16	94.7
rs:WP_025701826	DNA topoisomerase I [Paenibacillus forsythiae].	22.75	589	380	22	88	636	62	615	1e-16	94.7
rs:WP_026627609	DNA topoisomerase I [Dysgonomonas capnocytophagoides].	24.32	625	374	21	3	604	5	553	1e-16	94.7
rs:WP_019242321	DNA topoisomerase I [Bacillus massilioanorexius].	24.38	566	359	25	105	635	82	613	1e-16	94.4
rs:WP_037215870	DNA topoisomerase I [Rhizobium sp. IBUN].	22.05	694	419	26	1	630	1	636	1e-16	94.7
rs:XP_009279084	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Aptenodytes forsteri].	24.81	395	248	11	188	564	76	439	1e-16	94.7
rs:WP_021523431	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	94.7
rs:WP_014065398	topoisomerase I [Haemophilus parainfluenzae].	23.66	596	378	19	74	633	86	640	1e-16	94.7
rs:WP_013448201	DNA topoisomerase I [Neisseria lactamica].	22.70	727	453	26	3	679	5	672	1e-16	94.7
rs:WP_042160445	DNA topoisomerase I [Paenibacillus sp. G1].	24.16	592	368	25	88	636	62	615	1e-16	94.4
rs:WP_026444414	DNA topoisomerase I [Acinetobacter sp. UNC436CL71CviS28].	25.15	485	319	14	67	537	51	505	1e-16	94.7
rs:WP_024301152	DNA topoisomerase I [Pseudogulbenkiania sp. MAI-1].	23.08	663	420	23	3	630	5	612	1e-16	94.7
rs:WP_038919025	DNA topoisomerase I [Dickeya sp. MK7].	23.00	639	404	22	76	673	84	675	1e-16	94.7
rs:WP_009892959	DNA topoisomerase I [Peptoclostridium difficile].	24.79	718	415	31	3	675	5	642	1e-16	94.4
rs:WP_027720616	DNA topoisomerase I [Desulfovibrio zosterae].	23.19	677	412	24	3	640	5	612	1e-16	94.7
rs:WP_006201781	DNA topoisomerase I [Mesorhizobium amorphae].	22.43	700	406	24	1	630	1	633	1e-16	94.7
rs:WP_027662585	DNA topoisomerase 1 [Escherichia coli].	23.66	596	385	22	73	633	74	634	1e-16	94.7
rs:WP_019405754	topoisomerase I [Pseudomonas stutzeri].	23.27	477	302	12	187	633	194	636	1e-16	94.7
rs:WP_045926121	DNA topoisomerase I [Bacillus siamensis].	23.46	567	374	21	105	641	82	618	1e-16	94.4
rs:WP_016936131	DNA topoisomerase I [Bacillus siamensis].	23.46	567	374	21	105	641	82	618	1e-16	94.4
rs:WP_012547331	reverse gyrase [Dictyoglomus thermophilum].	23.98	563	325	22	3	536	586	1074	1e-16	95.1
rs:WP_003955190	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	1e-16	94.7
rs:WP_019539088	hypothetical protein [Proteiniphilum acetatigenes].	24.29	564	340	21	3	541	5	506	1e-16	94.7
tr:Q0T5C5_SHIF8	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.63	601	379	24	73	633	88	648	1e-16	94.7
rs:WP_019079493	topoisomerase I [Yersinia enterocolitica].	23.52	608	364	19	74	633	86	640	1e-16	94.7
rs:WP_003775245	DNA topoisomerase I [Neisseria elongata].	22.84	670	423	23	70	679	37	672	1e-16	94.7
rs:WP_039707018	DNA topoisomerase I, partial [marine actinobacterium MedAcidi-G3].	24.88	631	343	30	3	566	5	571	1e-16	94.4
rs:WP_001726005	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	94.7
rs:WP_039076930	DNA topoisomerase I [Enterobacter sp. Bisph2].	24.21	603	373	22	73	633	74	634	1e-16	94.7
rs:WP_043900714	hypothetical protein, partial [Parcubacteria bacterium RAAC4_OD1_1].	23.83	663	410	21	1	630	1	601	1e-16	94.4
rs:WP_021183094	DNA topoisomerase I [Pantoea sp. AS-PWVM4].	23.79	475	304	13	187	633	191	635	1e-16	94.7
rs:WP_027349138	DNA topoisomerase I [Halotalea alkalilenta].	23.23	607	364	21	74	633	90	641	1e-16	94.7
rs:WP_001705049	DNA topoisomerase I [Escherichia coli].	24.06	478	299	18	187	633	190	634	1e-16	94.7
rs:WP_012769871	MULTISPECIES: topoisomerase I [Dickeya].	22.45	646	403	20	75	673	81	675	1e-16	94.7
rs:WP_021414805	DNA topoisomerase I [Peptoclostridium difficile].	25.40	618	360	26	103	675	81	642	1e-16	94.4
rs:WP_001252809	topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	88	648	1e-16	94.7
rs:WP_028470945	DNA topoisomerase I [Neptunomonas japonica].	23.64	605	371	21	72	633	86	642	1e-16	94.7
rs:WP_034840251	DNA topoisomerase I [[Clostridium] cellulosi].	23.21	629	396	23	83	671	59	640	1e-16	94.4
rs:XP_009472958	PREDICTED: DNA topoisomerase 3-beta-1 [Nipponia nippon].	22.91	563	364	18	36	564	42	568	1e-16	94.7
rs:XP_009313180	putative DNA topoisomerase III, partial [Trypanosoma grayi].	22.31	614	393	20	3	577	6	574	1e-16	94.7
rs:WP_038704262	DNA topoisomerase I [Planococcus sp. PAMC 21323].	22.90	559	367	18	103	630	80	605	1e-16	94.4
rs:WP_037487916	DNA topoisomerase I [Snodgrassella alvi].	22.85	674	410	29	3	630	5	614	1e-16	94.7
rs:WP_004821709	DNA topoisomerase I [Peptoniphilus indolicus].	24.84	620	379	27	90	671	67	637	1e-16	94.4
rs:WP_005556886	topoisomerase I [Aggregatibacter actinomycetemcomitans].	23.94	472	307	12	187	633	196	640	1e-16	94.7
rs:WP_047005924	DNA topoisomerase I [Erythrobacter gangjinensis].	21.72	732	459	26	1	680	1	670	1e-16	94.7
rs:WP_013649945	topoisomerase I [Yersinia enterocolitica].	23.52	608	364	19	74	633	86	640	1e-16	94.7
rs:WP_002245394	DNA topoisomerase I [Neisseria meningitidis].	23.21	728	448	28	3	679	5	672	1e-16	94.7
rs:WP_018146992	DNA topoisomerase I [Henriciella marina].	24.19	682	407	29	1	629	1	625	1e-16	94.7
rs:WP_010197905	DNA topoisomerase I, partial [Pseudomonas amygdali].	24.21	475	300	14	187	633	59	501	1e-16	94.4
tr:A0A024GSB7_9STRA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.65	618	391	20	3	573	5	582	1e-16	94.7
tr:A0A098FAS6_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.86	560	375	20	105	635	82	613	1e-16	94.4
rs:WP_005169368	topoisomerase I [Yersinia enterocolitica].	23.52	608	364	19	74	633	86	640	1e-16	94.7
rs:XP_005370069	PREDICTED: DNA topoisomerase 3-beta-1 [Microtus ochrogaster].	22.89	629	399	23	3	585	5	593	1e-16	94.7
rs:WP_026393154	DNA topoisomerase I [Acetobacterium dehalogenans].	25.39	579	346	23	103	639	80	614	1e-16	94.4
rs:WP_015277422	DNA topoisomerase I [Pseudomonas stutzeri].	23.43	478	300	12	187	633	194	636	1e-16	94.7
rs:WP_019332831	topoisomerase I [Pseudomonas syringae].	23.48	592	382	20	74	633	87	639	1e-16	94.7
tr:F3EUA5_PSEA0	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	24.21	475	300	14	187	633	62	504	1e-16	94.4
rs:XP_005077629	PREDICTED: DNA topoisomerase 3-beta-1 [Mesocricetus auratus].	22.89	629	399	23	3	585	5	593	1e-16	94.7
tr:A9M455_NEIM0	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.56	641	405	23	89	679	47	652	1e-16	94.4
rs:WP_046786461	DNA topoisomerase I [Pseudomonas putida].	24.37	476	300	14	186	633	195	638	1e-16	94.7
tr:A0A0D2JXC3_9EURO	SubName: Full=Unplaced genomic scaffold supercont1.22, whole genome shotgun sequence {ECO:0000313|EMBL:KIX95179.1};	22.76	646	409	23	3	593	7	617	1e-16	94.4
tr:S5ZEH2_9CREN	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AGT35503.1};	23.38	616	399	23	3	583	6	583	1e-16	94.4
rs:WP_021552277	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	94.7
rs:WP_013509246	topoisomerase I [Pantoea sp. At-9b].	23.79	475	304	13	187	633	191	635	1e-16	94.7
rs:WP_022514491	GTP-sensing transcriptional pleiotropic repressor CodY [Roseburia sp. CAG:182].	23.89	561	355	18	90	616	67	589	1e-16	94.4
tr:C3BNQ9_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.21	560	373	20	105	635	75	606	1e-16	94.4
rs:WP_040506588	DNA topoisomerase I [Leptospira wolbachii].	22.68	604	379	14	87	630	63	638	1e-16	94.4
rs:WP_043198376	DNA topoisomerase I [Pseudomonas putida].	24.16	476	301	14	186	633	195	638	1e-16	94.7
rs:WP_012408434	DNA topoisomerase I [Nostoc punctiforme].	25.89	587	350	20	79	618	59	607	1e-16	94.4
rs:WP_042348935	DNA topoisomerase I [Bacillus sp. G2(2012b)].	23.57	560	357	20	105	629	82	605	1e-16	94.4
rs:WP_018285616	hypothetical protein [zeta proteobacterium SCGC AB-133-C04].	23.83	596	377	23	76	629	52	612	1e-16	94.4
rs:WP_016115962	MULTISPECIES: DNA topoisomerase 1 [Bacillus].	23.21	560	373	20	105	635	82	613	1e-16	94.4
rs:WP_032179017	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	94.7
tr:H0ZEB7_TAEGU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.91	563	364	18	36	564	26	552	1e-16	94.7
rs:WP_034616985	DNA topoisomerase I [Desulfosporosinus sp. Tol-M].	23.90	590	370	24	88	634	62	615	1e-16	94.4
rs:WP_044308551	DNA topoisomerase I [Pseudomonas syringae].	23.65	592	381	21	74	633	87	639	1e-16	94.7
rs:WP_005165857	topoisomerase I [Yersinia enterocolitica].	23.52	608	364	19	74	633	86	640	1e-16	94.7
tr:D8LYS1_BLAHO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.28	670	423	26	3	614	7	643	1e-16	94.7
rs:WP_005154109	topoisomerase I [Shigella sonnei].	23.63	601	379	24	73	633	74	634	1e-16	94.7
rs:WP_036586219	DNA topoisomerase I [Ochrobactrum anthropi].	23.62	707	387	30	1	629	1	632	1e-16	94.7
rs:WP_044927185	DNA topoisomerase I, partial [Roseburia inulinivorans].	23.95	622	385	22	90	671	67	640	1e-16	94.4
rs:WP_001422890	topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	94.7
rs:WP_023060391	DNA topoisomerase I subunit omega [Acinetobacter baumannii].	23.83	596	365	20	75	629	99	646	1e-16	94.7
tr:J7SJ75_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.66	674	423	22	3	636	36	644	1e-16	94.4
rs:WP_008122907	DNA topoisomerase I [Phyllobacterium sp. YR531].	24.35	694	398	31	1	629	1	632	1e-16	94.7
rs:WP_002355997	toprim domain protein, partial [Enterococcus faecium].	32.91	158	100	3	41	192	27	184	1e-16	89.7
rs:WP_001614507	DNA topoisomerase I [Escherichia coli].	23.79	601	378	24	73	633	74	634	1e-16	94.7
rs:WP_012093053	DNA topoisomerase I [Ochrobactrum anthropi].	23.62	707	387	30	1	629	1	632	1e-16	94.7
rs:WP_027094806	DNA topoisomerase I [[Clostridium] viride].	22.06	621	404	20	90	675	68	643	1e-16	94.7
rs:WP_026724184	DNA topoisomerase I [Flavobacterium sasangense].	24.72	530	331	16	3	521	5	477	1e-16	94.7
rs:WP_037122099	DNA topoisomerase I [Rhizobium sp. CF097].	23.01	691	416	29	1	630	1	636	1e-16	94.7
rs:XP_005421521	PREDICTED: DNA topoisomerase 3-beta-1 [Geospiza fortis].	22.91	563	364	18	36	564	24	550	1e-16	94.7
rs:WP_026515380	DNA topoisomerase I [Butyrivibrio sp. LB2008].	24.03	566	349	21	90	616	61	584	1e-16	94.4
rs:WP_011010569	DNA topoisomerase I [Clostridium perfringens].	23.40	705	401	26	2	630	4	645	1e-16	94.4
rs:WP_009531537	DNA topoisomerase I [Peptostreptococcaceae bacterium OBRC8].	24.82	681	386	32	3	635	4	606	1e-16	94.4
rs:WP_005248729	DNA topoisomerase I [Acinetobacter sp. CIP 51.11].	25.15	485	319	14	67	537	51	505	1e-16	94.4
tr:A0A091JBV2_9AVES	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.91	563	364	18	36	564	26	552	1e-16	94.7
rs:WP_027712113	DNA topoisomerase I [Dickeya chrysanthemi].	22.55	643	406	21	75	673	81	675	1e-16	94.7
rs:WP_042067134	DNA topoisomerase I, partial [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	94.4
rs:WP_044313220	DNA topoisomerase I [Pseudomonas syringae].	23.65	592	381	20	74	633	87	639	1e-16	94.7
rs:WP_029441257	DNA topoisomerase I [Bacillus mojavensis].	24.34	567	369	20	105	641	82	618	1e-16	94.4
rs:WP_035572607	DNA topoisomerase I [Hyphomonas adhaerens].	26.57	414	246	17	1	392	1	378	1e-16	94.7
rs:WP_014499436	topoisomerase I [Buchnera aphidicola].	24.33	563	366	16	74	614	79	603	1e-16	94.7
rs:WP_012101804	DNA topoisomerase I [Clostridium kluyveri].	24.50	649	392	22	2	616	4	588	1e-16	94.4
tr:A0A0D6PF16_9PROT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAN79454.1};	23.95	643	382	26	55	629	36	639	1e-16	94.7
rs:WP_043039794	DNA topoisomerase I [Vibrio parahaemolyticus].	22.90	594	390	16	75	633	86	646	1e-16	94.7
rs:XP_008922043	PREDICTED: DNA topoisomerase 3-beta-1 [Manacus vitellinus].	22.74	563	365	18	36	564	24	550	1e-16	94.7
tr:C6SJC0_NEIME	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.09	732	444	27	3	679	58	725	1e-16	94.7
rs:WP_023498024	Topoisomerase IA [uncultured archaeon A07HR67].	25.59	465	277	21	2	423	6	444	1e-16	94.0
rs:WP_034686384	DNA topoisomerase I [Acinetobacter baumannii].	25.15	485	319	14	67	537	51	505	1e-16	94.4
tr:A0A093PVT6_9PASS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.74	563	365	18	36	564	26	552	1e-16	94.7
tr:A0A099T0T3_METMT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.75	661	432	28	1	630	1	620	1e-16	94.4
rs:WP_035148387	DNA topoisomerase I [Campylobacter fetus].	25.43	519	308	22	100	578	72	551	1e-16	94.4
tr:R9A4C2_9LEPT	SubName: Full=Putative DNA topoisomerase I {ECO:0000313|EMBL:EOQ96952.1};	22.68	604	379	14	87	630	21	596	1e-16	94.0
rs:WP_035058842	DNA topoisomerase I [Andreprevotia chitinilytica].	23.03	595	390	19	74	630	51	615	1e-16	94.4
rs:WP_007674523	DNA topoisomerase I [Caulobacter sp. AP07].	21.86	700	404	25	1	630	1	627	1e-16	94.7
rs:WP_011328029	topoisomerase I [Pseudoalteromonas haloplanktis].	23.96	626	384	23	52	631	62	641	1e-16	94.7
rs:WP_036651426	DNA topoisomerase I [Paenibacillus pini].	23.97	584	379	22	88	636	62	615	1e-16	94.4
rs:WP_022238987	DNA topoisomerase [Lachnospiraceae bacterium CAG:364].	24.23	553	337	19	103	616	80	589	1e-16	94.4
tr:U4TQT7_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.19	583	368	21	90	635	62	607	1e-16	94.4
rs:WP_047035564	DNA topoisomerase I [Lactobacillus salivarius].	22.57	576	369	21	90	629	82	616	1e-16	94.4
rs:WP_038593555	DNA topoisomerase I [Paenibacillus sp. FSL H7-0357].	23.63	584	381	21	88	636	62	615	1e-16	94.4
rs:WP_017493823	topoisomerase I [gamma proteobacterium WG36].	22.57	647	397	21	76	673	82	673	1e-16	94.7
rs:WP_003380888	topoisomerase I [Pseudomonas syringae].	23.48	592	382	20	74	633	87	639	1e-16	94.7
rs:WP_022258149	DNA topoisomerase [Clostridium sp. CAG:508].	24.19	496	333	12	90	564	67	540	1e-16	94.4
rs:WP_021572102	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	94.7
rs:WP_006842975	DNA topoisomerase I [Dysgonomonas mossii].	23.08	585	358	18	3	569	5	515	1e-16	94.4
rs:WP_001619376	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	94.7
rs:WP_039517280	DNA topoisomerase I [Pectobacterium carotovorum].	24.08	598	373	21	74	633	81	635	1e-16	94.7
rs:WP_019023224	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	23.55	569	345	21	3	534	5	520	1e-16	94.7
rs:WP_042481986	DNA topoisomerase I [Vibrio diazotrophicus].	22.77	606	390	19	57	633	86	642	1e-16	94.7
rs:WP_016409792	DNA topoisomerase [Clostridium sp. CAG:1024].	24.27	511	335	15	90	574	67	551	1e-16	94.4
rs:WP_015371522	DNA topoisomerase I subunit omega [Pseudomonas poae].	23.37	475	304	12	187	633	197	639	1e-16	94.7
rs:WP_022109808	DNA topoisomerase [Prevotella sp. CAG:604].	23.71	599	367	17	3	580	5	534	1e-16	94.4
rs:WP_024512407	DNA topoisomerase I [Bradyrhizobium sp. ARR65].	24.64	690	403	30	1	630	1	633	1e-16	94.7
rs:WP_001761127	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	94.7
rs:WP_038391634	DNA topoisomerase I [Salmonella bongori].	23.71	603	376	24	73	633	74	634	1e-16	94.7
rs:WP_036752627	DNA topoisomerase I [Peptoniphilus lacrimalis].	22.87	717	437	29	3	678	5	646	1e-16	94.4
gp:BC002432_1	topoisomerase (DNA) III beta [Homo sapiens]	22.50	631	399	22	3	585	5	593	1e-16	94.4
rs:WP_001382542	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	94.4
tr:D0EG00_LEIDO	SubName: Full=DNA topoisomerase III beta {ECO:0000313|EMBL:ACX31684.1};	21.55	608	398	18	3	571	6	573	1e-16	94.4
rs:WP_017939227	topoisomerase I [Pseudomonas thermotolerans].	22.89	603	372	18	75	633	82	635	1e-16	94.4
tr:A6EMW3_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.49	536	317	21	3	521	5	480	1e-16	94.4
rs:WP_001707026	DNA topoisomerase I [Escherichia coli].	24.06	478	299	18	187	633	190	634	1e-16	94.4
rs:WP_037586178	DNA topoisomerase I [Stenoxybacter acetivorans].	22.69	683	400	27	3	630	5	614	1e-16	94.4
rs:XP_006213369	PREDICTED: DNA topoisomerase 3-beta-1 [Vicugna pacos].	22.12	633	399	23	3	585	5	593	1e-16	94.4
rs:WP_016589524	topoisomerase I [Yersinia pestis].	22.98	657	386	22	74	673	86	679	1e-16	94.4
rs:WP_025128846	DNA topoisomerase I [Pseudomonas sp. PH1b].	22.52	595	384	19	74	633	87	639	1e-16	94.4
tr:A0A076VXS8_BACMY	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:AIK35346.1};	26.98	341	220	11	351	675	14	341	1e-16	93.6
rs:WP_043299032	DNA topoisomerase I [Pseudomonas sp. HMP271].	23.21	474	308	11	186	633	193	636	1e-16	94.4
tr:A0A091ETB4_CORBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.79	566	361	20	36	564	26	552	1e-16	94.4
rs:WP_018029792	DNA topoisomerase I [Streptococcus ferus].	24.18	579	367	24	83	629	78	616	1e-16	94.4
tr:A0A0D6PWM0_KOMEU	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAN95180.1};	21.31	685	429	28	3	630	4	635	1e-16	94.7
rs:WP_035392076	DNA topoisomerase I [Bacillus sp. UNC125MFCrub1.1].	24.33	563	365	22	105	636	82	614	1e-16	94.4
rs:WP_042605792	DNA topoisomerase III, partial [Vibrio harveyi].	26.99	326	205	13	1	303	1	316	1e-16	91.3
rs:WP_010359499	DNA topoisomerase I [Neisseria gonorrhoeae].	22.42	727	455	25	3	679	5	672	1e-16	94.4
rs:WP_003679500	DNA topoisomerase I [Neisseria flavescens].	22.56	727	454	25	3	679	5	672	1e-16	94.4
tr:E6PFJ4_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CBH75230.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBH75230.1};	23.79	601	359	27	88	635	62	616	1e-16	94.4
rs:WP_031935302	DNA topoisomerase I, partial [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	94.4
rs:WP_039423665	DNA topoisomerase I, partial [Porphyromonas gulae].	27.18	287	189	8	347	623	11	287	1e-16	91.3
rs:WP_046971205	DNA topoisomerase I [Dyella japonica].	22.72	581	349	17	3	538	5	530	1e-16	94.4
rs:WP_037365465	DNA topoisomerase I [Selenomonas sp. FOBRC6].	21.66	674	423	22	3	636	50	658	1e-16	94.4
rs:WP_044155905	DNA topoisomerase I [Salinibacillus aidingensis].	24.34	567	369	20	105	641	82	618	1e-16	94.4
tr:A0A0A5LGL4_AERHY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.09	606	363	22	75	633	82	637	1e-16	94.4
rs:WP_018996076	DNA topoisomerase I [Hirschia maritima].	24.03	695	395	31	1	629	1	628	1e-16	94.4
rs:WP_019568140	DNA topoisomerase I [Thioalkalivibrio sp. ALMg13-2].	23.55	569	345	20	3	534	5	520	1e-16	94.4
rs:XP_012433502	PREDICTED: DNA topoisomerase 3-beta-1 [Taeniopygia guttata].	22.91	563	364	18	36	564	118	644	1e-16	94.7
rs:WP_016218473	DNA topoisomerase I [Dorea sp. 5-2].	22.56	616	366	21	90	629	67	647	1e-16	94.4
rs:WP_017684584	topoisomerase I [Pseudomonas syringae].	23.48	592	382	20	74	633	87	639	1e-16	94.4
rs:WP_007017743	topoisomerase I [Bermanella marisrubri].	23.74	594	370	21	74	629	91	639	1e-16	94.4
rs:WP_002230188	DNA topoisomerase I [Neisseria meningitidis].	22.83	727	452	26	3	679	5	672	1e-16	94.4
rs:WP_022276224	DNA topoisomerase [Bacteroides finegoldii CAG:203].	24.26	544	331	18	3	526	5	487	1e-16	94.4
rs:WP_046073425	DNA topoisomerase I [Salinivibrio sp. KP-1].	24.38	480	294	16	187	633	196	639	1e-16	94.4
rs:XP_012013093	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Ovis aries musimon].	22.20	626	407	21	3	585	5	593	1e-16	94.4
rs:WP_012722846	topoisomerase I [Pseudomonas fluorescens].	23.68	473	305	13	187	633	197	639	1e-16	94.4
rs:WP_036085525	DNA topoisomerase I [Listeria booriae].	23.54	565	369	22	103	635	80	613	1e-16	94.0
rs:XP_010326952	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Solanum lycopersicum].	22.10	552	376	15	105	631	55	577	1e-16	94.4
rs:WP_041035352	DNA topoisomerase I [Serratia marcescens].	23.85	608	362	20	74	633	80	634	1e-16	94.4
rs:WP_038268119	DNA topoisomerase I [[Clostridium] litorale].	23.72	683	400	30	3	639	5	612	1e-16	94.0
rs:WP_032576660	DNA topoisomerase I, partial [Bacteroides fragilis].	25.23	329	210	9	276	593	10	313	1e-16	91.3
rs:WP_020020763	hypothetical protein [alpha proteobacterium SCGC AAA160-J14].	24.25	697	410	27	1	639	1	637	1e-16	94.4
tr:B1KNL0_SHEWM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.09	602	371	21	74	631	104	657	1e-16	94.4
tr:H8YX88_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.62	610	385	22	76	630	61	638	1e-16	94.4
rs:WP_038898164	DNA topoisomerase I [Vibrio harveyi].	23.23	594	376	17	77	633	90	640	1e-16	94.4
rs:WP_012729597	topoisomerase I [Tolumonas auensis].	24.96	605	357	23	74	633	84	636	1e-16	94.4
rs:WP_003754393	DNA topoisomerase I [Neisseria polysaccharea].	22.70	727	453	26	3	679	5	672	1e-16	94.4
rs:WP_037089087	DNA topoisomerase I [Rhizobium sp. H41].	22.27	705	404	29	1	630	1	636	1e-16	94.4
rs:WP_035721465	DNA topoisomerase I [Gracilibacillus boraciitolerans].	24.73	566	363	24	103	635	80	615	1e-16	94.0
tr:A0A091SZH1_9AVES	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.91	563	364	18	36	564	26	552	1e-16	94.4
rs:WP_028171575	MULTISPECIES: DNA topoisomerase I [Bradyrhizobium].	23.03	686	418	23	1	630	1	632	1e-16	94.4
rs:WP_005137003	topoisomerase I [Shigella sonnei].	23.63	601	379	24	73	633	74	634	1e-16	94.4
rs:WP_005051290	DNA topoisomerase I [Acinetobacter beijerinckii].	23.66	579	355	19	90	629	117	647	1e-16	94.4
rs:WP_027076999	DNA topoisomerase I [Maribacter antarcticus].	24.20	653	405	20	3	621	5	601	1e-16	94.4
rs:WP_040855033	DNA topoisomerase I [Thiorhodovibrio sp. 970].	22.62	610	385	22	76	630	51	628	1e-16	94.4
rs:WP_008911059	DNA topoisomerase I subunit omega [Providencia burhodogranariea].	22.59	518	336	12	187	673	189	672	1e-16	94.4
rs:WP_015468187	DNA topoisomerase I [Micavibrio aeruginosavorus].	22.89	686	412	28	3	629	6	633	1e-16	94.4
rs:WP_001423441	topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	1e-16	94.4
rs:WP_036768081	DNA topoisomerase I [Photorhabdus asymbiotica].	22.28	534	318	16	187	673	190	673	1e-16	94.4
tr:C3APD2_BACMY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.21	560	373	20	105	635	75	606	1e-16	94.0
rs:WP_016910752	DNA topoisomerase I [Staphylococcus vitulinus].	24.30	572	369	18	90	630	67	605	1e-16	94.0
rs:WP_034118691	DNA topoisomerase I [Pseudomonas fluorescens].	23.68	473	305	13	187	633	197	639	1e-16	94.4
rs:WP_015486301	DNA topoisomerase I [Thalassolituus oleivorans].	24.21	599	361	24	74	629	91	639	1e-16	94.4
rs:WP_037177574	DNA topoisomerase I [Rhizobium sp. YR519].	23.06	707	396	31	1	630	1	636	1e-16	94.4
tr:E5VI15_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.07	565	362	17	83	616	60	588	1e-16	94.0
rs:WP_005738758	MULTISPECIES: topoisomerase I [Pseudomonas syringae group].	23.48	592	382	20	74	633	87	639	1e-16	94.4
rs:WP_024212414	MULTISPECIES: DNA topoisomerase I [Escherichia].	23.17	600	383	22	73	633	74	634	1e-16	94.4
rs:WP_042237164	DNA topoisomerase I [Paenibacillus sp. FSL R5-0912].	23.46	584	382	20	88	636	62	615	1e-16	94.0
rs:WP_029927305	DNA topoisomerase I [Ochrobactrum sp. UNC390CL2Tsu3S39].	23.62	707	387	30	1	629	1	632	1e-16	94.4
tr:I0DNS9_PROSM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.69	520	333	14	187	673	123	606	1e-16	94.4
rs:WP_002215352	DNA topoisomerase I [Neisseria meningitidis].	22.83	727	452	26	3	679	5	672	1e-16	94.4
tr:A0A0D3L9T6_9BACT	SubName: Full=DNA topoisomerase i {ECO:0000313|EMBL:AHM58619.1};	25.05	547	327	19	3	526	5	491	1e-16	94.4
rs:WP_036223571	hypothetical protein [Mesoaciditoga lauensis].	24.57	647	387	24	2	616	4	581	1e-16	94.4
rs:WP_018176248	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	23.55	569	345	20	3	534	5	520	1e-16	94.4
rs:XP_002199057	PREDICTED: DNA topoisomerase 3-beta-1 [Taeniopygia guttata].	22.91	563	364	18	36	564	189	715	1e-16	94.4
rs:WP_018986690	DNA topoisomerase I [Methylophilus methylotrophus].	23.19	664	389	24	2	614	3	596	1e-16	94.4
rs:WP_028521365	DNA topoisomerase I [Ruminococcus flavefaciens].	23.67	562	357	18	90	616	66	590	1e-16	94.0
rs:WP_004826339	DNA topoisomerase I [Peptoniphilus lacrimalis].	22.87	717	437	29	3	678	5	646	1e-16	94.0
rs:WP_003471661	DNA topoisomerase I [Clostridium perfringens].	23.40	705	401	26	2	630	4	645	1e-16	94.0
rs:WP_017813666	DNA topoisomerase I [Paenibacillus sp. A9].	23.37	569	368	23	103	636	80	615	1e-16	94.0
rs:WP_022491918	DNA topoisomerase [Clostridium sp. CAG:813].	24.64	548	325	17	168	667	14	521	1e-16	94.0
rs:WP_018122573	hypothetical protein [Wohlfahrtiimonas chitiniclastica].	23.89	561	352	17	3	534	5	519	1e-16	94.4
tr:A0A091UPR8_NIPNI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.91	563	364	18	36	564	26	552	1e-16	94.4
rs:WP_034574126	DNA topoisomerase I [Mageeibacillus indolicus].	23.39	667	409	24	3	629	5	609	1e-16	94.0
rs:WP_020313017	DNA topoisomerase I subunit omega [Pseudomonas syringae].	23.48	592	382	20	74	633	87	639	1e-16	94.4
rs:WP_007513531	DNA topoisomerase I [Rhodanobacter denitrificans].	22.55	612	392	16	77	638	54	633	1e-16	94.4
rs:WP_021064912	hypothetical protein [Agrococcus pavilionensis].	23.79	496	303	15	77	528	67	531	1e-16	94.4
tr:S6V5Y6_PSESF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.48	592	382	20	74	633	44	596	1e-16	94.4
rs:WP_024921477	MULTISPECIES: DNA topoisomerase I [Afipia].	24.20	690	406	31	1	630	1	633	1e-16	94.4
rs:WP_043895310	DNA topoisomerase I, partial [Porphyromonas gingivalis].	37.67	146	73	5	1	135	1	139	1e-16	88.2
rs:WP_042013731	DNA topoisomerase I [Aeromonas fluvialis].	23.93	606	364	23	75	633	82	637	1e-16	94.4
rs:WP_009526510	DNA topoisomerase I [Peptostreptococcaceae bacterium CM2].	24.82	681	386	32	3	635	4	606	1e-16	94.0
rs:WP_000513582	topoisomerase I [Salmonella bongori].	23.58	598	383	21	73	633	74	634	1e-16	94.4
rs:WP_035119821	DNA topoisomerase I [Cohnella panacarvi].	24.15	588	371	23	88	635	62	614	1e-16	94.0
rs:WP_041418062	DNA topoisomerase I [Shewanella woodyi].	23.09	602	371	21	74	631	88	641	1e-16	94.4
rs:WP_007424321	DNA topoisomerase I [Acidiphilium sp. PM].	22.35	631	408	23	55	630	28	631	1e-16	94.4
rs:WP_003677938	DNA topoisomerase I [Neisseria cinerea].	22.99	670	422	23	70	679	37	672	1e-16	94.4
rs:XP_010396475	PREDICTED: DNA topoisomerase 3-beta-1 [Corvus cornix cornix].	22.79	566	361	20	36	564	24	550	1e-16	94.4
tr:W4WJ63_ATTCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.88	656	428	17	3	601	5	626	2e-16	94.0
rs:WP_017848775	topoisomerase I [Pseudomonas veronii].	23.84	474	305	13	186	633	196	639	2e-16	94.4
rs:WP_003218973	MULTISPECIES: topoisomerase I [Pseudomonas].	23.84	474	303	15	187	633	197	639	2e-16	94.4
rs:WP_008007080	topoisomerase I [Pseudomonas sp. GM50].	23.16	475	307	14	186	633	196	639	2e-16	94.4
tr:A0A0B4IPU2_VIBHA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.23	594	376	17	77	633	90	640	2e-16	94.4
rs:WP_005450368	MULTISPECIES: topoisomerase I [Vibrio].	23.23	594	376	17	77	633	90	640	2e-16	94.4
rs:WP_003099575	DNA topoisomerase I [Streptococcus iniae].	22.53	586	368	22	83	629	84	622	2e-16	94.0
rs:WP_042048623	DNA topoisomerase I [Aeromonas simiae].	23.66	486	293	15	186	633	192	637	2e-16	94.4
rs:WP_003370501	topoisomerase I [Pseudomonas syringae].	23.48	592	382	20	74	633	87	639	2e-16	94.4
rs:WP_011528644	DNA topoisomerase I [Streptococcus pyogenes].	23.04	560	357	18	103	629	103	621	2e-16	94.0
rs:WP_040958459	DNA topoisomerase I [Sinorhizobium fredii].	22.80	693	415	29	1	630	1	636	2e-16	94.4
rs:WP_032881097	DNA topoisomerase I [Pseudomonas sp. BRG-100].	23.17	492	313	15	77	541	62	515	2e-16	94.0
rs:WP_020254513	hypothetical protein [Parcubacteria bacterium SCGC AAA036-E14].	23.93	677	389	26	1	629	1	599	2e-16	94.0
rs:WP_002244762	DNA topoisomerase I [Neisseria meningitidis].	22.83	727	452	26	3	679	5	672	2e-16	94.0
rs:WP_031390299	DNA topoisomerase I [Clostridium sp. KNHs209].	25.00	560	349	19	90	616	67	588	2e-16	94.0
rs:WP_024234990	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	2e-16	94.4
rs:WP_029789004	DNA topoisomerase I [Vibrio harveyi].	23.23	594	376	17	77	633	90	640	2e-16	94.4
rs:WP_016998603	DNA topoisomerase I [Staphylococcus lentus].	24.78	573	365	20	90	630	67	605	2e-16	94.0
rs:WP_001454855	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	2e-16	94.4
rs:WP_002995012	DNA topoisomerase I [Streptococcus pyogenes].	23.04	560	357	19	103	629	103	621	2e-16	94.0
rs:XP_003079855	COG0550: Topoisomerase IA (ISS) [Ostreococcus tauri].	24.20	533	340	17	84	573	103	614	2e-16	94.4
rs:WP_041266580	DNA topoisomerase I, partial [Gemmatimonas aurantiaca].	23.90	590	369	21	90	629	146	705	2e-16	94.4
tr:A0A099P2L0_ISSOR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.44	585	353	20	46	585	6	546	2e-16	93.6
rs:WP_042356248	DNA topoisomerase I [Bacillus sp. MT2].	23.51	570	360	22	105	635	82	614	2e-16	94.0
rs:WP_021570479	DNA topoisomerase 1 [Escherichia coli].	23.84	604	374	23	73	633	74	634	2e-16	94.4
rs:WP_018938918	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	23.55	569	345	20	3	534	5	520	2e-16	94.4
gpu:AP014685_9795	DNA topoisomerase I [Bradyrhizobium diazoefficiens]	23.03	686	418	23	1	630	1	632	2e-16	94.4
rs:WP_001359511	topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	2e-16	94.4
rs:WP_018144652	DNA topoisomerase I [Thioalkalivibrio sp. AKL6].	23.55	569	345	20	3	534	5	520	2e-16	94.4
rs:WP_002352835	DNA topoisomerase, partial [Enterococcus faecium].	25.00	340	220	7	158	472	23	352	2e-16	91.7
gp:AM902716_1304	pseudogene [Bordetella petrii]	29.15	247	153	7	408	641	16	253	2e-16	90.5
rs:WP_022419704	DNA topoisomerase [Eubacterium dolichum CAG:375].	23.47	669	401	25	3	629	4	603	2e-16	94.0
rs:XP_010579932	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Haliaeetus leucocephalus].	22.91	563	364	18	36	564	24	550	2e-16	94.4
rs:WP_010735743	DNA topoisomerase 1 [Enterococcus mundtii].	25.65	573	347	25	103	635	81	614	2e-16	94.0
rs:WP_039732367	DNA topoisomerase I [Komagataeibacter intermedius].	22.16	528	344	17	84	571	60	560	2e-16	94.4
rs:WP_021828753	MULTISPECIES: DNA topoisomerase I [Bacteria].	24.53	579	333	23	3	534	5	526	2e-16	94.4
rs:WP_031895793	DNA topoisomerase III, partial [Staphylococcus aureus].	25.98	281	193	5	346	620	20	291	2e-16	91.3
rs:WP_046661409	DNA topoisomerase I [Microcystis aeruginosa].	25.20	611	351	22	3	560	4	561	2e-16	94.4
rs:WP_044420078	DNA topoisomerase I [Pseudomonas syringae group genomosp. 3].	23.48	592	382	20	74	633	87	639	2e-16	94.4
rs:WP_014456565	DNA topoisomerase I [Spirochaeta africana].	23.36	625	376	21	3	574	6	580	2e-16	94.4
rs:XP_004386256	PREDICTED: DNA topoisomerase 3-beta-1 [Trichechus manatus latirostris].	22.63	632	397	22	3	585	5	593	2e-16	94.4
rs:WP_002240198	DNA topoisomerase I [Neisseria meningitidis].	22.83	727	452	26	3	679	5	672	2e-16	94.0
rs:WP_006701213	DNA topoisomerase I [Facklamia ignava].	24.62	585	360	26	90	635	67	609	2e-16	94.0
rs:WP_032292753	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	2e-16	94.4
rs:WP_001484536	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	2e-16	94.4
tr:G4ADB6_AGGAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.29	241	153	8	262	493	17	251	2e-16	90.9
rs:WP_027978427	DNA topoisomerase I [gamma proteobacterium L18].	23.11	476	306	15	186	633	195	638	2e-16	94.4
rs:WP_017666344	DNA topoisomerase I [Porphyrobacter sp. AAP82].	22.71	656	395	25	1	610	1	590	2e-16	94.4
rs:WP_027508567	DNA topoisomerase I [Rhizobium sullae].	24.22	669	383	30	38	630	16	636	2e-16	94.4
rs:WP_012582441	reverse gyrase [Dictyoglomus turgidum].	24.82	568	314	24	3	536	584	1072	2e-16	94.4
rs:WP_008375020	DNA topoisomerase I [Coprococcus comes].	23.98	563	355	18	90	616	67	592	2e-16	94.0
rs:WP_024658808	DNA topoisomerase I [Pseudomonas syringae].	23.48	592	382	20	74	633	87	639	2e-16	94.4
tr:A0A090M290_OSTTA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.20	533	340	17	84	573	143	654	2e-16	94.4
rs:WP_032930423	DNA topoisomerase I [Mesorhizobium loti].	22.97	701	401	25	1	630	1	633	2e-16	94.4
rs:WP_002234458	DNA topoisomerase I [Neisseria meningitidis].	22.83	727	452	26	3	679	5	672	2e-16	94.0
rs:WP_010751238	DNA topoisomerase 1 [Enterococcus villorum].	24.87	571	354	22	103	635	81	614	2e-16	94.0
rs:WP_022289901	DNA topoisomerase [Oscillibacter sp. CAG:155].	21.89	562	370	17	90	616	68	595	2e-16	94.0
tr:K5U6E8_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.23	594	376	17	77	633	83	633	2e-16	94.4
rs:WP_003436352	DNA topoisomerase I subunit omega [Pseudomonas syringae].	23.48	592	382	20	74	633	87	639	2e-16	94.4
rs:WP_041704980	DNA topoisomerase I [Providencia stuartii].	22.69	520	333	14	187	673	120	603	2e-16	94.0
rs:WP_034578557	DNA topoisomerase I, partial [Helicobacter canis].	23.59	568	367	15	76	615	53	581	2e-16	94.0
rs:WP_017477200	topoisomerase I [Pseudomonas sp. PAMC 26793].	23.84	474	303	15	187	633	197	639	2e-16	94.4
rs:WP_016131882	DNA topoisomerase 1 [Bacillus cereus].	23.21	560	373	20	105	635	82	613	2e-16	94.0
rs:WP_016338588	DNA topoisomerase I [Spiroplasma chrysopicola].	25.86	495	316	15	55	533	38	497	2e-16	94.0
rs:WP_018650578	DNA topoisomerase I [Thioalkalivibrio sp. ALMg3].	23.55	569	345	20	3	534	5	520	2e-16	94.4
rs:WP_017799901	topoisomerase I [Erwinia toletana].	23.45	597	378	20	75	633	80	635	2e-16	94.4
rs:WP_005538876	topoisomerase I [Aggregatibacter actinomycetemcomitans].	23.95	476	302	13	187	633	196	640	2e-16	94.4
rs:WP_043253486	DNA topoisomerase I [Pseudomonas knackmussii].	22.86	595	382	16	74	633	86	638	2e-16	94.4
rs:WP_022076044	DNA topoisomerase [Firmicutes bacterium CAG:212].	24.24	561	353	20	90	616	80	602	2e-16	94.0
rs:WP_035186290	DNA topoisomerase I [Acidiphilium sp. JA12-A1].	22.35	631	408	23	55	630	28	631	2e-16	94.4
rs:WP_002249911	DNA topoisomerase I [Neisseria meningitidis].	23.56	641	405	23	89	679	67	672	2e-16	94.0
rs:WP_001964157	DNA topoisomerase [Helicobacter pylori].	25.15	485	327	15	75	536	46	517	2e-16	94.0
rs:XP_008301799	PREDICTED: DNA topoisomerase 3-beta-1 [Stegastes partitus].	22.35	613	383	19	3	564	5	575	2e-16	94.4
rs:WP_011941732	DNA topoisomerase I [Acidiphilium cryptum].	22.35	631	408	23	55	630	28	631	2e-16	94.4
rs:WP_010176358	topoisomerase I [Pseudomonas sp. PAMC 25886].	23.84	474	303	15	187	633	197	639	2e-16	94.4
rs:WP_011087871	DNA topoisomerase I [Bradyrhizobium diazoefficiens].	23.03	686	418	23	1	630	1	632	2e-16	94.0
rs:WP_031915413	DNA topoisomerase III, partial [Staphylococcus aureus].	30.25	238	138	5	388	615	2	221	2e-16	91.3
rs:WP_018398472	DNA topoisomerase I [filamentous cyanobacterium ESFC-1].	23.09	628	371	22	3	574	4	575	2e-16	94.4
rs:WP_010212659	DNA topoisomerase I, partial [Pseudomonas amygdali].	24.21	475	300	14	187	633	51	493	2e-16	94.0
rs:WP_016670597	DNA topoisomerase I [Neisseria meningitidis].	22.83	727	452	26	3	679	5	672	2e-16	94.0
tr:A0A060CQA5_HELPX	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:AIA98746.1};	24.64	491	322	13	75	536	46	517	2e-16	94.0
tr:B1X1Z5_CYAA5	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	612	358	20	85	641	86	651	2e-16	94.0
rs:WP_018168364	DNA topoisomerase I [Thioalkalivibrio sp. ALMg9].	23.55	569	345	20	3	534	5	520	2e-16	94.0
tr:W8YLE3_9BACL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.65	575	359	23	103	636	45	580	2e-16	94.0
rs:WP_003181746	MULTISPECIES: DNA topoisomerase I [Bacillus].	23.71	561	369	21	105	635	82	613	2e-16	94.0
rs:WP_017781938	topoisomerase I [Aeromonas hydrophila].	23.93	606	364	22	75	633	82	637	2e-16	94.0
rs:WP_022635683	DNA topoisomerase I [Chitinivibrio alkaliphilus].	23.40	547	354	18	96	610	73	586	2e-16	94.0
tr:G0V1G7_TRYCI	SubName: Full=Putative uncharacterized protein TCIL3000_11_9530 {ECO:0000313|EMBL:CCC95488.1};	22.58	598	381	21	3	560	6	561	2e-16	94.0
rs:WP_029473387	DNA topoisomerase I [Clostridiales bacterium VE202-08].	23.80	664	373	24	2	614	3	584	2e-16	94.0
rs:XP_003877019	putative DNA topoisomerase III [Leishmania mexicana MHOM/GT/2001/U1103].	21.55	608	398	18	3	571	6	573	2e-16	94.0
rs:WP_008094100	topoisomerase I [Pseudomonas sp. GM84].	25.05	479	293	16	186	633	196	639	2e-16	94.0
rs:WP_018857025	DNA topoisomerase I [Rhizobium sp. 42MFCr.1].	22.05	694	419	26	1	630	1	636	2e-16	94.0
rs:WP_039480851	DNA topoisomerase I [Pectobacterium carotovorum].	23.91	598	374	21	74	633	81	635	2e-16	94.0
tr:A0A093G994_PICPB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.91	563	364	18	36	564	26	552	2e-16	94.0
rs:WP_039693966	DNA topoisomerase I [Dickeya solani].	23.00	639	404	22	76	673	84	675	2e-16	94.0
rs:WP_040133195	DNA topoisomerase I [Providencia stuartii].	23.26	473	309	10	187	633	189	633	2e-16	94.0
tr:A0A024GTK3_9STRA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.65	618	389	21	3	573	5	580	2e-16	94.4
rs:WP_008151419	topoisomerase I [Pseudomonas sp. GM41(2012)].	23.16	475	307	14	186	633	196	639	2e-16	94.0
rs:WP_024992856	DNA topoisomerase, partial [Prevotella amnii].	31.08	222	141	7	455	673	44	256	2e-16	90.5
rs:WP_041306969	DNA topoisomerase I, partial [Herpetosiphon aurantiacus].	23.48	609	379	20	77	630	54	630	2e-16	94.0
rs:WP_022220378	DNA topoisomerase [Coprococcus comes CAG:19].	23.98	563	355	18	90	616	67	592	2e-16	94.0
rs:WP_039950861	DNA topoisomerase I [Bacteroides clarus].	23.92	623	374	22	3	596	5	556	2e-16	94.0
rs:WP_016235984	DNA topoisomerase 1 [Escherichia coli].	23.63	601	379	24	73	633	74	634	2e-16	94.0
rs:WP_043118135	DNA topoisomerase I [Solemya velum gill symbiont].	22.19	685	410	25	1	630	1	617	2e-16	94.0
rs:WP_025280338	DNA topoisomerase I [Ectothiorhodospira haloalkaliphila].	22.93	567	351	20	3	534	5	520	2e-16	94.0
rs:WP_005346800	MULTISPECIES: DNA topoisomerase I [Eubacterium].	23.90	615	361	21	90	630	67	648	2e-16	94.0
rs:WP_037383320	DNA topoisomerase I [Sinorhizobium americanum].	23.05	694	412	29	1	630	1	636	2e-16	94.0
rs:WP_043644116	DNA topoisomerase I [Nocardioides alkalitolerans].	24.06	636	370	27	2	577	4	586	2e-16	94.0
rs:WP_007635410	DNA topoisomerase I [Glaciecola psychrophila].	24.12	626	388	21	48	629	56	638	2e-16	94.0
rs:WP_043062780	DNA topoisomerase I [Ochrobactrum anthropi].	23.62	707	387	30	1	629	1	632	2e-16	94.0
rs:WP_046762942	DNA topoisomerase I [Sphingobium chungbukense].	21.92	666	431	22	1	629	1	614	2e-16	94.0
tr:A0A0D6BYJ6_9PSED	SubName: Full=DNA topoisomerase I subunit omega {ECO:0000313|EMBL:BAQ79945.1};	22.28	588	394	16	74	633	87	639	2e-16	94.0
rs:WP_003985132	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	2e-16	94.0
rs:WP_023611066	DNA topoisomerase I [Streptococcus pyogenes].	23.09	563	353	19	103	629	103	621	2e-16	94.0
rs:WP_003022384	DNA topoisomerase I [Blautia hansenii].	24.05	553	338	19	103	616	80	589	2e-16	93.6
rs:WP_016427618	DNA topoisomerase 1 [Paenisporosarcina sp. HGH0030].	24.37	558	355	21	105	629	82	605	2e-16	93.6
rs:WP_024941857	DNA topoisomerase I [Aeromonas hydrophila].	23.93	606	364	22	75	633	82	637	2e-16	94.0
rs:WP_011072651	topoisomerase I [Shewanella oneidensis].	23.60	483	294	16	186	631	197	641	2e-16	94.0
rs:WP_045923410	DNA topoisomerase I [Lactobacillus mellis].	24.70	583	367	21	90	635	85	632	2e-16	94.0
rs:WP_046519309	DNA topoisomerase I [Rheinheimera sp. IITR-13].	23.15	596	378	20	75	631	75	629	2e-16	94.0
rs:WP_042652626	DNA topoisomerase I [Aeromonas encheleia].	23.76	606	365	22	75	633	82	637	2e-16	94.0
rs:WP_010981052	DNA topoisomerase I [Neisseria meningitidis].	22.83	727	452	26	3	679	5	672	2e-16	94.0
rs:WP_033061924	DNA topoisomerase I [Pseudomonas mandelii].	23.16	475	307	14	186	633	196	639	2e-16	94.0
rs:WP_009546432	MULTISPECIES: DNA topoisomerase I [Cyanothece].	24.35	612	362	19	85	641	71	636	2e-16	93.6
rs:WP_025663347	DNA topoisomerase I [Aquimarina megaterium].	25.56	536	328	20	3	526	5	481	2e-16	94.0
tr:G1VGY8_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGW46164.1};	31.42	226	135	7	455	673	10	222	2e-16	90.1
rs:WP_002238601	DNA topoisomerase I [Neisseria meningitidis].	22.83	727	452	26	3	679	5	672	2e-16	94.0
rs:WP_000513600	topoisomerase I [Escherichia fergusonii].	23.53	595	387	20	73	633	74	634	2e-16	94.0
rs:WP_015477970	DNA topoisomerase I subunit omega [Pseudomonas denitrificans].	23.43	478	302	13	186	633	194	637	2e-16	94.0
rs:WP_039141172	DNA topoisomerase I [Flavihumibacter solisilvae].	24.71	599	364	22	3	580	5	537	2e-16	94.0
rs:WP_007933178	topoisomerase I [Pseudomonas sp. GM18].	23.69	477	302	15	186	633	196	639	2e-16	94.0
tr:Q0SSB8_CLOPS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.47	703	403	26	2	630	4	645	2e-16	93.6
rs:WP_002218552	DNA topoisomerase I [Neisseria meningitidis].	22.83	727	452	26	3	679	5	672	2e-16	94.0
rs:WP_038979973	DNA topoisomerase I [Pseudomonas fluorescens].	23.16	475	307	14	186	633	196	639	2e-16	94.0
rs:WP_002354369	hypothetical protein, partial [Enterococcus faecium].	26.67	240	159	6	413	639	15	250	2e-16	90.1
rs:WP_024790332	DNA topoisomerase I [Lebetimonas sp. JH292].	24.96	657	398	25	3	629	5	596	2e-16	94.0
rs:WP_041139083	DNA topoisomerase I [Clostridiaceae bacterium GM1].	23.60	661	406	25	2	629	4	598	2e-16	93.6
rs:WP_043928301	DNA topoisomerase I [Bacillus licheniformis].	23.71	561	369	21	105	635	82	613	2e-16	93.6
rs:WP_007907779	topoisomerase I [Pseudomonas sp. GM102].	23.16	475	307	14	186	633	196	639	2e-16	94.0
rs:WP_019593470	DNA topoisomerase I [Thioalkalivibrio sp. ALM2T].	23.55	569	345	20	3	534	5	520	2e-16	94.0
rs:WP_039805487	DNA topoisomerase I [Azotobacter chroococcum].	23.86	591	381	20	74	633	85	637	2e-16	94.0
tr:J6XY22_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJY30884.1}; Flags: Fragment;	26.67	240	159	6	413	639	16	251	2e-16	90.1
rs:WP_043206689	DNA topoisomerase I [Pseudomonas putida].	25.10	478	292	16	187	633	196	638	2e-16	94.0
rs:WP_002250953	DNA topoisomerase I [Neisseria meningitidis].	22.83	727	452	26	3	679	5	672	2e-16	94.0
tr:D3R1W8_MAGIU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.54	667	408	24	3	629	5	609	2e-16	94.0
rs:WP_007603302	DNA topoisomerase I [Bradyrhizobium sp. WSM1253].	23.09	706	427	25	1	647	1	649	2e-16	94.0
rs:WP_013073533	DNA topoisomerase I [Zunongwangia profunda].	24.47	666	380	25	3	618	5	597	2e-16	94.0
rs:WP_032359226	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	2e-16	94.0
rs:WP_046047844	DNA topoisomerase I [Pseudomonas fluorescens].	23.16	475	307	14	186	633	196	639	2e-16	94.0
rs:WP_032808585	DNA topoisomerase I [Oenococcus oeni].	23.58	581	372	21	83	630	66	607	2e-16	93.6
rs:WP_047336170	DNA topoisomerase I [Pseudomonas fluorescens].	23.17	479	300	14	187	633	197	639	2e-16	94.0
rs:WP_021398006	DNA topoisomerase I [Peptoclostridium difficile].	24.79	718	415	31	3	675	5	642	2e-16	93.6
rs:WP_020428718	DNA topoisomerase I [Vibrio fluvialis].	24.90	502	311	13	163	633	176	642	2e-16	94.0
rs:WP_018705151	DNA topoisomerase I [Bacillus fordii].	23.23	564	372	21	103	635	80	613	2e-16	93.6
rs:WP_028009192	DNA topoisomerase I [Solimonas flava].	23.21	504	313	16	76	533	53	528	2e-16	94.0
rs:WP_007341842	DNA topoisomerase I [Neisseria bacilliformis].	22.12	728	456	24	3	679	5	672	2e-16	94.0
rs:WP_013798929	DNA topoisomerase I [Methanotorris igneus].	25.78	512	313	17	1	480	2	478	2e-16	94.4
rs:WP_022005438	GTP-sensing transcriptional pleiotropic repressor CodY [Firmicutes bacterium CAG:194].	23.65	630	377	23	90	671	67	640	2e-16	93.6
rs:WP_025785060	MULTISPECIES: DNA topoisomerase I [Sporosarcina].	23.71	561	368	19	100	630	77	607	2e-16	93.6
rs:WP_004799485	DNA topoisomerase I [[Eubacterium] dolichum].	23.62	669	400	25	3	629	4	603	2e-16	93.6
tr:K2F5I4_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.96	677	380	27	1	629	1	597	2e-16	93.6
rs:WP_010456356	topoisomerase I [Pseudomonas mandelii].	23.16	475	307	14	186	633	196	639	2e-16	94.0
rs:WP_045749618	DNA topoisomerase I [Acholeplasma oculi].	24.96	601	367	22	44	618	30	572	2e-16	93.2
rs:WP_018325938	DNA topoisomerase I [Rhizobium giardinii].	23.01	691	416	29	1	630	1	636	2e-16	94.0
rs:WP_002349796	hypothetical protein, partial [Enterococcus faecium].	26.67	240	159	6	413	639	12	247	2e-16	90.1
rs:WP_045894874	DNA topoisomerase I [Escherichia coli].	23.28	597	386	22	73	633	74	634	2e-16	94.0
rs:WP_027071533	DNA topoisomerase I [Luteimonas sp. J29].	24.25	569	351	19	3	538	5	526	2e-16	94.0
rs:WP_028287613	DNA topoisomerase I [Oceanicola nanhaiensis].	21.70	682	424	21	1	630	1	624	2e-16	94.0
rs:WP_024681926	DNA topoisomerase I [Pseudomonas syringae].	23.48	592	382	20	74	633	87	639	2e-16	94.0
rs:WP_047131249	DNA topoisomerase I [Staphylococcus condimenti].	23.79	597	382	20	90	649	67	627	2e-16	93.6
rs:XP_007743880	DNA topoisomerase III [Cladophialophora psammophila CBS 110553].	22.96	649	404	25	3	593	7	617	2e-16	93.6
tr:F3PJ55_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.92	623	374	22	3	596	28	579	2e-16	94.0
rs:WP_028000105	DNA topoisomerase I [Sinorhizobium arboris].	22.40	692	419	26	1	630	1	636	2e-16	94.0
rs:WP_027896820	DNA topoisomerase I [Pseudomonas thermotolerans].	22.32	596	384	16	75	633	82	635	2e-16	94.0
rs:WP_032654924	DNA topoisomerase I [Pseudomonas syringae].	22.77	593	385	19	74	633	87	639	2e-16	94.0
rs:WP_029299451	DNA topoisomerase I [Aeromonas hydrophila].	24.09	606	363	22	75	633	82	637	2e-16	94.0
rs:WP_007789732	DNA topoisomerase I [Rhizobium sp. CF122].	21.76	694	421	26	1	630	1	636	2e-16	94.0
rs:WP_009177887	DNA topoisomerase I [Silicibacter sp. TrichCH4B].	23.47	703	405	30	1	630	1	643	2e-16	94.0
rs:WP_013639815	DNA topoisomerase I [Acidiphilium multivorum].	22.35	631	408	23	55	630	28	631	2e-16	94.0
rs:WP_006458716	DNA topoisomerase I [Synechococcus sp. PCC 7335].	24.83	584	349	23	79	614	59	600	2e-16	93.6
rs:WP_012009947	DNA topoisomerase I [Bacillus pumilus].	23.93	560	371	21	105	636	82	614	2e-16	93.6
rs:WP_041421399	DNA topoisomerase I [Neisseria gonorrhoeae].	22.56	727	454	25	3	679	5	672	2e-16	93.6
rs:WP_016897101	DNA topoisomerase I [Aerococcus viridans].	23.51	570	369	20	90	629	68	600	2e-16	93.6
rs:WP_026890284	DNA topoisomerase I [[Clostridium] aerotolerans].	24.33	563	352	18	90	616	67	591	2e-16	93.6
rs:WP_024074081	topoisomerase I [Pseudomonas sp. TKP].	23.68	473	305	13	187	633	197	639	2e-16	94.0
rs:WP_007568290	MULTISPECIES: DNA topoisomerase I [Bacteroides].	23.30	618	394	19	3	604	5	558	2e-16	93.6
rs:WP_036692472	DNA topoisomerase I [Paenibacillus sp. FSL R7-269].	23.09	680	408	26	3	636	5	615	2e-16	93.6
rs:WP_024671025	DNA topoisomerase I [Pseudomonas syringae].	23.44	593	381	21	74	633	87	639	2e-16	94.0
rs:WP_009440258	DNA topoisomerase I [Selenomonas sp. oral taxon 138].	22.19	676	417	23	3	636	50	658	2e-16	93.6
rs:WP_032025368	DNA topoisomerase I [Acinetobacter baumannii].	23.83	596	365	20	75	629	99	646	2e-16	94.0
tr:C1ABE5_GEMAT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.04	570	358	20	90	614	114	653	2e-16	94.0
gpu:CP010423_1540	DNA topoisomerase I [Pragia fontium]	23.20	638	404	20	76	673	77	668	2e-16	94.0
rs:WP_017925209	DNA topoisomerase I [Thioalkalivibrio sp. HL-Eb18].	22.91	563	356	17	3	534	5	520	2e-16	94.0
rs:WP_011268332	DNA topoisomerase I [Pseudomonas syringae].	22.77	593	385	19	74	633	87	639	2e-16	94.0
tr:L8UF82_AGGAC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.95	476	302	13	187	633	196	640	2e-16	94.0
rs:WP_037987568	DNA topoisomerase I [Thalassospira permensis].	22.54	701	421	24	1	639	1	641	2e-16	94.0
rs:WP_005074608	topoisomerase I [Shigella flexneri].	23.63	601	379	24	73	633	74	634	2e-16	94.0
tr:K1RIM1_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC43504.1}; Flags: Fragment;	33.33	210	127	6	467	669	102	305	2e-16	90.9
rs:WP_021291589	MULTISPECIES: DNA topoisomerase I [Virgibacillus].	24.96	569	353	24	105	635	82	614	2e-16	93.6
rs:WP_015808006	DNA topoisomerase I [Pedobacter heparinus].	24.52	522	330	17	77	578	54	531	2e-16	94.0
rs:WP_005540121	DNA topoisomerase I [Johnsonella ignava].	25.22	559	350	20	90	616	67	589	2e-16	93.6
rs:WP_008592235	DNA topoisomerase I [Leptospira licerasiae].	25.66	608	348	24	55	610	28	583	2e-16	93.2
rs:WP_021692710	DNA topoisomerase I [Loktanella cinnabarina].	22.71	656	367	25	1	587	1	585	2e-16	94.0
rs:WP_013784485	topoisomerase I [Alteromonas sp. SN2].	23.84	604	381	19	65	629	75	638	2e-16	94.0
rs:WP_023605114	DNA topoisomerase I [Streptococcus pyogenes].	23.09	563	353	19	103	629	103	621	2e-16	93.6
rs:WP_032816112	DNA topoisomerase I [Oenococcus oeni].	23.58	581	372	21	83	630	66	607	2e-16	93.6
rs:WP_038634524	DNA topoisomerase I [Pseudomonas chlororaphis].	23.69	612	382	20	77	639	62	637	2e-16	93.6
rs:WP_027604240	DNA topoisomerase I [Pseudomonas sp. LAMO17WK12:I2].	23.63	474	306	13	186	633	196	639	2e-16	94.0
tr:K6K499_KLEOX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.95	610	372	22	73	633	74	634	2e-16	94.0
rs:WP_039565854	DNA topoisomerase I [Serratia marcescens].	23.68	608	363	20	74	633	80	634	2e-16	94.0
rs:WP_034953704	DNA topoisomerase I [Erythrobacter sp. JL475].	22.33	645	411	21	1	610	1	590	2e-16	94.0
rs:WP_024863841	DNA topoisomerase I [Entomoplasma somnilux].	25.04	671	388	27	3	625	4	607	2e-16	93.6
rs:WP_033865378	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	2e-16	94.0
rs:WP_043746353	DNA topoisomerase I [Oceanicola sp. 22II-S11g].	22.37	684	414	25	1	629	1	622	2e-16	94.0
rs:WP_034123499	DNA topoisomerase I, partial [Peptococcaceae bacterium BICA1-7].	22.78	597	361	21	3	561	8	542	2e-16	93.6
rs:WP_036879037	DNA topoisomerase I [Prevotella oryzae].	22.74	598	375	18	3	580	5	535	2e-16	93.6
rs:WP_018287834	DNA topoisomerase I [zeta proteobacterium SCGC AB-133-G06].	22.40	616	406	21	55	631	28	610	2e-16	93.6
rs:WP_045958545	DNA topoisomerase I [Xenorhabdus poinarii].	24.01	479	298	15	187	633	190	634	2e-16	94.0
rs:WP_002233406	DNA topoisomerase I [Neisseria meningitidis].	22.56	727	454	25	3	679	5	672	2e-16	93.6
rs:WP_027113602	DNA topoisomerase I [Lachnospiraceae bacterium NK4A144].	23.89	628	391	22	90	675	67	649	2e-16	93.6
rs:WP_009851878	DNA topoisomerase I [beta proteobacterium KB13].	24.48	674	406	29	2	630	3	618	2e-16	93.6
tr:V7PWA5_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.83	663	410	21	1	630	1	601	2e-16	93.6
rs:WP_006447066	DNA topoisomerase I [Alicyclobacillus hesperidum].	22.57	536	363	18	103	614	80	587	2e-16	93.6
rs:WP_004920164	topoisomerase I [Providencia stuartii].	23.69	477	302	14	187	633	189	633	2e-16	94.0
rs:WP_026701049	DNA topoisomerase I [Bacillus aidingensis].	22.54	559	364	18	105	629	83	606	2e-16	93.6
gpu:CP011509_6665	DNA topoisomerase I [Archangium gephyra]	22.66	693	424	27	3	640	88	723	2e-16	94.0
rs:WP_011060262	topoisomerase I [Pseudomonas protegens].	23.17	479	300	14	187	633	197	639	2e-16	94.0
rs:WP_010021434	DNA topoisomerase I [Lactobacillus fructivorans].	24.17	575	375	21	83	629	78	619	2e-16	93.6
rs:XP_009510457	PREDICTED: DNA topoisomerase 3-beta-1, partial [Phalacrocorax carbo].	22.91	563	364	18	36	564	40	566	2e-16	93.6
rs:WP_001719627	DNA topoisomerase III, partial [Salmonella enterica].	32.49	277	150	10	434	681	3	271	2e-16	90.1
rs:WP_023060017	DNA topoisomerase I [Peptoniphilus sp. BV3AC2].	23.44	704	434	25	3	671	5	638	2e-16	93.6
rs:WP_011588296	topoisomerase I [Alcanivorax borkumensis].	22.69	595	383	19	76	631	93	649	2e-16	94.0
rs:WP_020370685	MULTISPECIES: DNA topoisomerase I [Chlamydia].	23.35	775	420	31	3	670	5	712	2e-16	93.6
tr:A0A0A1H296_9LACO	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:BAP86821.1};	35.80	162	96	4	69	223	5	165	2e-16	89.0
rs:WP_047302981	DNA topoisomerase I [Pseudomonas fluorescens].	22.28	588	394	16	74	633	87	639	2e-16	94.0
rs:WP_039737107	DNA topoisomerase I [Hassallia byssoidea].	22.99	622	379	17	3	574	4	575	2e-16	94.0
rs:WP_022264915	DNA topoisomerase [Clostridium sp. CAG:352].	23.91	573	353	20	90	616	66	601	2e-16	93.6
rs:WP_032888794	DNA topoisomerase I [Pseudomonas sp. RIT357].	23.31	472	308	12	187	633	197	639	2e-16	94.0
rs:WP_027671233	DNA topoisomerase I [Rheinheimera baltica].	24.12	684	367	31	65	673	63	669	2e-16	93.6
rs:WP_002259562	DNA topoisomerase I [Neisseria meningitidis].	23.87	641	403	24	89	679	67	672	2e-16	93.6
rs:WP_007797415	DNA topoisomerase I [Pelagibaca bermudensis].	22.80	592	343	21	1	534	1	536	2e-16	94.0
rs:WP_013100547	DNA topoisomerase I [Methanocaldococcus infernus].	29.75	326	199	13	1	312	1	310	2e-16	93.6
rs:WP_013100547	DNA topoisomerase I [Methanocaldococcus infernus].	23.77	345	204	11	307	629	462	769	6e-08	66.6
rs:WP_036519729	DNA topoisomerase I [Nitrincola sp. A-D6].	22.91	611	358	20	76	633	93	643	2e-16	93.6
rs:WP_038877308	DNA topoisomerase I [Serratia marcescens].	23.68	608	363	20	74	633	80	634	2e-16	93.6
rs:WP_038633076	MULTISPECIES: DNA topoisomerase I [Yersinia].	24.01	608	361	21	74	633	86	640	2e-16	93.6
rs:WP_016247142	DNA topoisomerase 1 [Escherichia coli].	23.46	601	380	24	73	633	74	634	2e-16	93.6
rs:WP_034419954	DNA topoisomerase I [Clostridiales bacterium DRI-13].	23.40	594	393	19	15	581	4	562	2e-16	93.6
rs:XP_012194243	hypothetical protein SPRG_00629 [Saprolegnia parasitica CBS 223.65].	21.54	636	411	22	3	594	4	595	2e-16	94.0
rs:WP_011017773	DNA topoisomerase I [Streptococcus pyogenes].	23.09	563	353	19	103	629	103	621	2e-16	93.6
rs:WP_026712288	DNA topoisomerase I [Flavobacterium daejeonense].	25.47	534	322	21	3	521	5	477	2e-16	93.6
rs:WP_014084443	DNA topoisomerase I [Flavobacterium branchiophilum].	25.61	531	325	20	3	521	5	477	2e-16	93.6
rs:WP_043047499	DNA topoisomerase I [Pseudomonas fluorescens].	23.68	473	305	13	187	633	197	639	2e-16	93.6
rs:WP_001516492	MULTISPECIES: topoisomerase I [Escherichia].	23.24	598	385	23	73	633	74	634	2e-16	93.6
rs:WP_015378045	MULTISPECIES: DNA topoisomerase I, omega subunit [Serratia].	23.68	608	363	20	74	633	80	634	2e-16	93.6
rs:WP_006558567	DNA topoisomerase I [Acetobacter tropicalis].	22.92	637	400	23	55	630	28	634	2e-16	93.6
rs:WP_041057468	DNA topoisomerase I [Jeotgalibacillus campisalis].	24.49	437	283	14	163	574	138	552	2e-16	93.6
rs:XP_009329019	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Pygoscelis adeliae].	24.81	395	248	11	188	564	76	439	2e-16	93.6
tr:F1QNX4_DANRE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.46	635	389	25	3	585	5	594	2e-16	93.6
rs:WP_022676334	DNA topoisomerase I [Novosphingobium sp. B-7].	21.55	673	428	22	1	629	1	617	2e-16	93.6
rs:WP_013261363	topoisomerase I [gamma proteobacterium HdN1].	22.80	601	397	17	61	629	76	641	2e-16	93.6
rs:WP_018925317	MULTISPECIES: topoisomerase I [Pseudomonas].	23.69	477	302	15	186	633	196	639	2e-16	93.6
rs:WP_005619805	DNA topoisomerase I subunit omega [Ruegeria mobilis].	23.47	703	405	30	1	630	1	643	2e-16	93.6
rs:WP_017020611	topoisomerase I [Aliivibrio logei].	24.22	607	367	22	77	639	89	646	2e-16	93.6
rs:WP_004837937	hypothetical protein, partial [Anaerococcus tetradius].	35.71	154	82	3	249	396	8	150	2e-16	87.8
rs:WP_010508168	DNA topoisomerase I [Komagataeibacter europaeus].	21.17	685	430	28	3	630	4	635	2e-16	93.6
rs:WP_038832236	DNA topoisomerase I [Yersinia pestis].	22.83	657	387	22	74	673	86	679	2e-16	93.6
rs:WP_031952082	DNA topoisomerase I [Acinetobacter baumannii].	23.83	596	365	20	75	629	99	646	2e-16	93.6
rs:WP_032464379	DNA topoisomerase I [Streptococcus pyogenes].	22.86	560	358	19	103	629	103	621	2e-16	93.6
rs:WP_011888870	DNA topoisomerase I [Streptococcus pyogenes].	23.09	563	353	19	103	629	103	621	2e-16	93.6
rs:WP_011054502	DNA topoisomerase I [Streptococcus pyogenes].	23.09	563	353	19	103	629	103	621	2e-16	93.6
rs:WP_028484168	DNA topoisomerase I [Thioalkalivibrio sp. ALE17].	22.74	576	352	18	3	534	5	531	2e-16	93.6
rs:WP_016975262	topoisomerase I [Pseudomonas fluorescens].	23.75	480	298	14	186	633	196	639	2e-16	93.6
rs:WP_022273096	DNA topoisomerase [Clostridium sp. CAG:58].	23.99	567	349	20	90	616	67	591	2e-16	93.2
rs:WP_023801090	DNA topoisomerase I [Mesorhizobium sp. L48C026A00].	23.12	705	395	28	1	630	1	633	2e-16	93.6
rs:WP_024835713	DNA topoisomerase I [Clostridium sp. 12(A)].	24.91	566	345	19	90	616	67	591	2e-16	93.2
rs:WP_036762982	DNA topoisomerase I [Peptostreptococcus sp. MV1].	25.13	585	342	24	90	629	68	601	2e-16	93.2
rs:WP_043315150	hypothetical protein [Pseudomonas sp. PI1].	28.09	178	121	3	1	177	1	172	2e-16	88.6
rs:WP_007974049	topoisomerase I [Pseudomonas sp. GM33].	23.69	477	302	15	186	633	196	639	2e-16	93.6
rs:WP_011284793	DNA topoisomerase I [Streptococcus pyogenes].	23.09	563	353	19	103	629	103	621	2e-16	93.6
rs:WP_028641269	DNA topoisomerase I [Novosphingobium acidiphilum].	22.12	624	404	20	55	629	27	617	2e-16	93.6
rs:WP_030128417	DNA topoisomerase I [Pseudomonas sp. QTF5].	23.21	474	306	14	187	633	197	639	2e-16	93.6
rs:WP_003700733	DNA topoisomerase I [Neisseria gonorrhoeae].	22.56	727	454	25	3	679	5	672	2e-16	93.6
rs:WP_035073895	DNA topoisomerase I [Anditalea andensis].	24.86	551	343	14	3	539	5	498	2e-16	93.6
rs:WP_014612281	DNA topoisomerase I [Streptococcus dysgalactiae].	22.81	583	370	20	83	629	83	621	2e-16	93.6
rs:WP_022091340	DNA topoisomerase [Lachnospiraceae bacterium CAG:25].	24.16	567	359	17	83	616	60	588	2e-16	93.2
rs:WP_025298389	DNA topoisomerase I [Aggregatibacter actinomycetemcomitans].	23.48	477	303	13	187	633	196	640	2e-16	93.6
rs:WP_016222617	DNA topoisomerase I [Lachnospiraceae bacterium 3-2].	24.03	620	387	24	90	671	67	640	2e-16	93.2
tr:A0A068RFI3_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.57	576	365	20	3	537	4	539	2e-16	92.8
rs:WP_002232259	DNA topoisomerase I [Neisseria meningitidis].	22.83	727	452	26	3	679	5	672	2e-16	93.6
rs:WP_025385032	DNA topoisomerase I [Legionella oakridgensis].	24.00	625	391	28	55	630	29	618	2e-16	93.6
rs:WP_020650998	DNA topoisomerase I [Solimonas variicoloris].	23.56	505	310	17	76	533	53	528	2e-16	93.6
rs:WP_004395085	topoisomerase I [Vibrio metschnikovii].	24.25	602	366	19	75	633	87	641	2e-16	93.6
rs:WP_028954651	DNA topoisomerase I [Sulfitobacter sp. 20_GPM-1509m].	21.74	736	424	28	1	660	1	660	3e-16	93.6
tr:A4N0B7_HAEIF	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.91	359	229	9	187	533	196	529	3e-16	92.8
rs:WP_007531862	DNA topoisomerase I [Rhizobium mesoamericanum].	22.05	694	419	26	1	630	1	636	3e-16	93.6
rs:WP_038176919	DNA topoisomerase I [Vibrio pacinii].	22.82	631	359	23	57	633	83	639	3e-16	93.6
rs:WP_002245788	DNA topoisomerase I [Neisseria meningitidis].	22.83	727	452	26	3	679	5	672	3e-16	93.6
rs:WP_045542387	DNA topoisomerase I [Acetobacter tropicalis].	22.92	637	400	23	55	630	28	634	3e-16	93.6
rs:WP_033169858	DNA topoisomerase I [Selenomonas sp. ND2010].	24.73	554	359	21	90	616	86	608	3e-16	93.6
rs:WP_025648226	DNA topoisomerase I [Clostridium perfringens].	23.26	705	402	26	2	630	4	645	3e-16	93.2
rs:WP_021397791	DNA topoisomerase I [Peptoclostridium difficile].	24.50	653	383	25	3	616	5	586	3e-16	93.2
rs:WP_005544715	topoisomerase I [Aggregatibacter actinomycetemcomitans].	23.48	477	303	13	187	633	196	640	3e-16	93.6
rs:WP_022462183	DNA topoisomerase [Blautia sp. CAG:37].	23.43	559	360	17	90	616	67	589	3e-16	93.2
rs:WP_022171308	GTP-sensing transcriptional pleiotropic repressor CodY [Blautia sp. CAG:52].	22.85	569	351	20	90	616	67	589	3e-16	93.2
rs:WP_014108707	topoisomerase I [Glaciecola nitratireducens].	24.13	605	378	24	65	629	75	638	3e-16	93.6
rs:WP_014094621	DNA topoisomerase I [Candidatus Arthromitus sp. SFB-rat-Yit].	25.78	547	328	21	103	614	80	583	3e-16	93.2
tr:A9AYY1_HERA2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.48	609	379	20	77	630	54	630	3e-16	93.6
rs:WP_022187731	DNA topoisomerase [Azospirillum sp. CAG:260].	23.73	687	401	29	1	629	1	622	3e-16	93.6
rs:WP_041205259	DNA topoisomerase I [Aeromonas media].	23.47	605	368	21	75	633	82	637	3e-16	93.6
rs:WP_001559015	DNA topoisomerase 1 [Escherichia coli].	23.46	601	380	24	73	633	74	634	3e-16	93.6
rs:WP_035379360	DNA topoisomerase I [Acetobacter tropicalis].	22.92	637	400	23	55	630	28	634	3e-16	93.6
rs:WP_034102544	DNA topoisomerase I [Pseudomonas fluorescens].	23.63	474	306	13	186	633	196	639	3e-16	93.6
rs:WP_036940356	DNA topoisomerase I [Providencia stuartii].	23.58	475	305	12	187	633	189	633	3e-16	93.6
rs:WP_032204508	DNA topoisomerase I [Escherichia coli].	23.63	601	379	24	73	633	74	634	3e-16	93.6
rs:WP_036963747	DNA topoisomerase I [Providencia alcalifaciens].	23.79	475	304	12	187	633	198	642	3e-16	93.6
rs:WP_006658706	topoisomerase I [Providencia alcalifaciens].	23.79	475	304	12	187	633	198	642	3e-16	93.6
rs:WP_024121390	DNA topoisomerase I [Bacillus mojavensis].	24.34	567	369	20	105	641	82	618	3e-16	93.2
tr:E3D5G6_NEIM7	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.95	732	445	27	3	679	58	725	3e-16	93.6
rs:WP_003683147	DNA topoisomerase I [Lactobacillus fermentum].	24.53	579	361	26	88	629	85	624	3e-16	93.2
rs:WP_014499986	topoisomerase I [Buchnera aphidicola].	24.02	562	369	14	74	614	79	603	3e-16	93.6
rs:WP_001526939	DNA topoisomerase 1 [Escherichia coli].	23.45	597	385	22	73	633	74	634	3e-16	93.6
rs:WP_019648305	topoisomerase I [Pseudomonas sp. 45MFCol3.1].	23.69	477	302	15	186	633	196	639	3e-16	93.6
rs:WP_036888715	DNA topoisomerase I [Porphyromonas crevioricanis].	23.78	534	335	16	3	520	5	482	3e-16	93.6
rs:WP_012549908	topoisomerase I [Aliivibrio salmonicida].	24.22	607	367	22	77	639	89	646	3e-16	93.6
rs:WP_047235284	DNA topoisomerase I [Streptococcus pyogenes].	23.09	563	353	19	103	629	103	621	3e-16	93.2
rs:WP_030126679	DNA topoisomerase I [Streptococcus pyogenes].	23.09	563	353	19	103	629	103	621	3e-16	93.2
rs:WP_033543929	DNA topoisomerase I [Planococcus sp. CAU13].	22.98	557	369	18	103	630	80	605	3e-16	93.2
tr:A8K4N2_HUMAN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.50	631	399	22	3	585	5	593	3e-16	93.6
rs:WP_015666349	DNA topoisomerase I [Bradyrhizobium oligotrophicum].	23.98	688	409	29	1	630	1	632	3e-16	93.6
rs:WP_036292883	DNA topoisomerase I [Methylobacter whittenburyi].	25.43	409	251	15	157	534	136	521	3e-16	93.6
rs:WP_017409144	topoisomerase I [Aeromonas hydrophila].	24.09	606	363	22	75	633	82	637	3e-16	93.6
rs:WP_011927356	DNA topoisomerase I [Bradyrhizobium sp. ORS 278].	24.27	688	407	29	1	630	1	632	3e-16	93.6
rs:WP_021550866	DNA topoisomerase 1 [Escherichia coli].	23.17	600	383	22	73	633	74	634	3e-16	93.6
rs:WP_008057949	topoisomerase I [Pseudomonas sp. GM78].	23.21	474	308	13	186	633	196	639	3e-16	93.6
rs:WP_013384550	DNA topoisomerase I [Ketogulonicigenium vulgare].	23.04	690	404	28	1	630	1	623	3e-16	93.6
rs:WP_035474507	DNA topoisomerase I [Gammaproteobacteria bacterium MFB021].	23.39	620	375	20	61	633	76	642	3e-16	93.6
rs:WP_033723606	DNA topoisomerase I, partial [Helicobacter pylori].	24.49	486	329	14	75	536	46	517	3e-16	92.8
rs:WP_028744828	DNA topoisomerase I [Rhizobium mesoamericanum].	21.90	694	420	24	1	630	1	636	3e-16	93.6
rs:WP_008073063	topoisomerase I [Pseudomonas sp. GM79].	23.16	475	307	14	186	633	196	639	3e-16	93.6
rs:WP_028509937	DNA topoisomerase I [Ruminococcus sp. NK3A76].	23.71	561	363	17	103	629	79	608	3e-16	93.2
rs:WP_012700082	topoisomerase I [Azotobacter vinelandii].	23.63	601	370	21	75	633	84	637	3e-16	93.6
rs:WP_045697622	DNA topoisomerase I [Hyphomonas sp. BRH_c22].	23.46	682	413	28	1	629	1	626	3e-16	93.6
tr:A0A072CGV2_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.90	657	400	28	38	630	11	631	3e-16	93.6
rs:WP_014730265	DNA topoisomerase I [Mesotoga prima].	23.57	594	371	17	2	571	4	538	3e-16	93.2
rs:WP_026654728	DNA topoisomerase I [Butyrivibrio sp. AE3003].	23.19	565	355	19	90	616	61	584	3e-16	93.2
rs:WP_036979408	DNA topoisomerase I [Providencia alcalifaciens].	23.79	475	304	12	187	633	198	642	3e-16	93.6
rs:WP_019271676	DNA topoisomerase I [Neisseria sicca].	22.69	670	424	23	70	679	37	672	3e-16	93.2
rs:WP_004373408	DNA topoisomerase I [Prevotella oris].	24.08	598	363	19	3	578	5	533	3e-16	93.2
rs:WP_035759138	DNA topoisomerase I [Arthrospira platensis].	23.36	578	340	21	3	530	4	528	3e-16	93.6
tr:F0LSG3_VIBFN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.59	619	369	18	57	633	26	582	3e-16	93.6
rs:WP_032822705	DNA topoisomerase I [Oenococcus oeni].	23.41	581	373	21	83	630	66	607	3e-16	93.2
tr:A0A024GSX9_9STRA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.53	617	391	20	4	573	1	577	3e-16	93.6
rs:WP_025903084	MULTISPECIES: DNA topoisomerase I [Tatumella].	22.31	493	289	14	187	633	190	634	3e-16	93.6
rs:WP_024262109	DNA topoisomerase I [Escherichia coli].	23.45	597	385	22	73	633	74	634	3e-16	93.6
rs:WP_027484108	DNA topoisomerase I [Rhodanobacter sp. OR87].	22.39	612	393	16	77	638	54	633	3e-16	93.6
rs:WP_036975684	DNA topoisomerase I [Providencia alcalifaciens].	23.48	477	303	13	187	633	198	642	3e-16	93.6
tr:E8R4T3_ISOPI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.44	581	360	21	90	631	184	724	3e-16	93.6
rs:WP_017790186	topoisomerase I [Vibrio vulnificus].	24.14	613	384	22	60	633	69	639	3e-16	93.6
rs:WP_034994474	DNA topoisomerase I [Lactobacillus vini].	22.89	603	376	21	90	645	79	639	3e-16	93.2
tr:B4RPY3_NEIG2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.68	732	447	26	3	679	21	688	3e-16	93.2
rs:WP_032820757	DNA topoisomerase I [Oenococcus oeni].	23.41	581	373	21	83	630	66	607	3e-16	93.2
rs:WP_010563749	topoisomerase I [Pseudomonas extremaustralis].	23.63	474	306	13	186	633	196	639	3e-16	93.6
rs:WP_038213506	DNA topoisomerase I [Xenophilus azovorans].	22.12	651	419	23	67	678	51	652	3e-16	93.2
rs:WP_001385318	DNA topoisomerase 1 [Escherichia coli].	23.45	597	385	22	73	633	74	634	3e-16	93.6
tr:W7QXB4_9ALTE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.40	643	412	19	73	673	28	625	3e-16	93.2
rs:WP_003234049	DNA topoisomerase I subunit omega [Pseudomonas fluorescens].	23.73	472	306	14	187	633	197	639	3e-16	93.6
rs:WP_010350249	MULTISPECIES: DNA topoisomerase I subunit omega [Escherichia].	23.19	595	389	20	73	633	74	634	3e-16	93.6
rs:WP_045443510	DNA topoisomerase I [Citrobacter sp. S-77].	23.28	597	386	22	73	633	74	634	3e-16	93.6
tr:K1W611_ARTPT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.36	578	340	21	3	530	12	536	3e-16	93.6
rs:WP_036832001	DNA topoisomerase I [Pontibacillus litoralis].	24.15	559	357	22	105	629	82	607	3e-16	93.2
rs:WP_028108824	DNA topoisomerase I [Ferrimonas futtsuensis].	23.80	479	302	15	186	633	198	644	3e-16	93.6
rs:WP_036965781	DNA topoisomerase I [Providencia alcalifaciens].	23.48	477	303	13	187	633	198	642	3e-16	93.6
rs:WP_017526655	topoisomerase I [Pseudomonas fluorescens].	23.68	473	305	13	187	633	197	639	3e-16	93.6
rs:WP_031430985	hypothetical protein [Vibrio parahaemolyticus].	21.75	630	397	18	3	564	2	603	3e-16	93.2
rs:WP_029791739	DNA topoisomerase I [[Clostridium] mangenotii].	24.57	578	334	25	103	631	81	605	3e-16	93.2
rs:WP_038055559	hypothetical protein [Thermodesulfobacterium hydrogeniphilum].	25.00	556	351	19	55	581	27	545	3e-16	92.8
rs:WP_045109699	DNA topoisomerase I [Moritella viscosa].	23.57	594	376	22	77	633	93	645	3e-16	93.6
rs:WP_028239585	DNA topoisomerase I [Pseudomonas azotifigens].	23.62	597	375	20	75	633	84	637	3e-16	93.6
rs:WP_009132458	DNA topoisomerase I [Bacteroides oleiciplenus].	23.35	621	390	20	3	601	5	561	3e-16	93.2
rs:XP_006938803	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Felis catus].	23.36	578	363	20	3	537	5	545	3e-16	93.2
tr:F4SWU8_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.45	597	385	22	73	633	96	656	3e-16	93.6
tr:W1D4K4_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.98	631	400	25	83	673	5	589	3e-16	93.2
rs:WP_042630808	DNA topoisomerase I [Helicobacter pylori].	24.80	492	320	14	75	536	46	517	3e-16	93.2
tr:U3ICG2_ANAPL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.81	395	248	11	188	564	52	415	3e-16	93.2
rs:WP_017291142	hypothetical protein [Leptolyngbya boryana].	23.56	662	391	24	2	614	4	599	3e-16	93.2
rs:WP_003059104	DNA topoisomerase I, partial [Streptococcus dysgalactiae].	22.81	583	370	20	83	629	50	588	3e-16	93.2
rs:WP_033082724	DNA topoisomerase I [Colwellia psychrerythraea].	22.47	663	414	23	65	680	75	684	3e-16	93.6
rs:WP_037007718	DNA topoisomerase I, partial [Pseudomonas fluorescens].	23.17	479	300	14	187	633	61	503	3e-16	93.2
rs:WP_010630966	DNA topoisomerase I [Sporolactobacillus vineae].	24.51	567	361	22	105	635	82	617	3e-16	93.2
tr:W4RQI6_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE46705.1};	37.24	145	87	3	77	219	3	145	3e-16	87.4
rs:WP_039035873	DNA topoisomerase I [Shewanella sp. ECSMB14102].	22.84	613	363	21	74	633	88	643	3e-16	93.2
rs:WP_036996267	DNA topoisomerase I, partial [Pseudomonas fluorescens].	23.17	479	300	14	187	633	53	495	3e-16	93.2
rs:NP_001099331	DNA topoisomerase 3-beta-1 [Rattus norvegicus].	23.36	608	383	23	3	564	5	575	3e-16	93.2
rs:WP_021768179	DNA topoisomerase I [Leptotrichia sp. oral taxon 225].	23.82	617	377	21	2	589	4	556	3e-16	93.2
rs:WP_006661696	DNA topoisomerase I subunit omega [Providencia alcalifaciens].	23.48	477	303	13	187	633	198	642	3e-16	93.2
rs:WP_034491437	DNA topoisomerase I [Afifella pfennigii].	22.08	684	427	24	1	630	1	632	3e-16	93.2
rs:WP_038966363	DNA topoisomerase I [Bradyrhizobium sp. CCBAU 41267].	23.07	685	417	23	1	629	1	631	3e-16	93.6
tr:W6SQD0_9CYAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.40	577	341	21	3	530	4	528	3e-16	93.6
rs:WP_022656303	DNA topoisomerase I [Desulfovibrio sp. Dsv1].	23.69	650	402	25	76	676	53	657	3e-16	93.2
rs:WP_022490361	DNA topoisomerase [Clostridium sp. CAG:567].	24.52	518	324	14	90	574	67	550	3e-16	93.2
rs:WP_010535667	MULTISPECIES: DNA topoisomerase I [Bacteroides].	23.90	544	333	18	3	526	5	487	3e-16	93.2
rs:WP_011184520	DNA topoisomerase I [Streptococcus pyogenes].	22.86	560	358	19	103	629	103	621	3e-16	93.2
rs:WP_035463685	DNA topoisomerase I [Lactobacillus ceti].	23.72	565	351	22	103	629	74	596	3e-16	93.2
tr:A0A0D6MI16_9PROT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAN52913.1};	22.35	631	407	23	55	629	37	640	3e-16	93.2
rs:WP_026612485	DNA topoisomerase I [Ensifer sp. TW10].	23.15	691	414	29	1	630	1	635	3e-16	93.2
rs:WP_007022807	topoisomerase I [Neptuniibacter caesariensis].	23.44	610	381	21	65	633	79	643	3e-16	93.2
rs:WP_045085262	DNA topoisomerase I [[Clostridium] cellulosi].	23.21	629	396	24	83	671	59	640	3e-16	93.2
rs:WP_012816917	DNA topoisomerase I [Zymomonas mobilis].	23.16	678	413	26	1	629	1	619	3e-16	93.6
rs:WP_023508917	DNA topoisomerase I [Sporolactobacillus laevolacticus].	23.85	566	366	22	105	635	82	617	3e-16	93.2
rs:WP_017254452	topoisomerase I [Pseudomonas tolaasii].	23.63	474	306	13	186	633	196	639	3e-16	93.2
rs:WP_018286108	hypothetical protein [zeta proteobacterium SCGC AB-137-I08].	23.41	628	407	22	38	629	23	612	3e-16	93.2
tr:I4E2V2_NEIME	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.68	646	398	24	89	679	120	725	3e-16	93.2
tr:L1MJJ4_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.31	487	278	20	72	525	57	500	3e-16	93.2
rs:WP_005347733	topoisomerase I [Aeromonas veronii].	23.93	606	364	23	75	633	82	637	3e-16	93.2
rs:WP_010026557	DNA topoisomerase I [Sporolactobacillus inulinus].	24.34	567	363	22	105	635	82	618	3e-16	93.2
rs:WP_038893575	DNA topoisomerase I [Yersinia pestis].	22.83	657	387	22	74	673	86	679	3e-16	93.2
rs:WP_022551015	DNA topoisomerase 1 [Vibrio nigripulchritudo].	25.39	508	301	16	163	633	174	640	3e-16	93.2
rs:WP_026619340	DNA topoisomerase I [Ensifer sp. WSM1721].	23.15	691	414	29	1	630	1	635	3e-16	93.2
rs:XP_006099576	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Myotis lucifugus].	25.00	416	260	13	188	585	76	457	3e-16	93.2
tr:E2XNF4_PSEFL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.68	473	305	13	187	633	89	531	3e-16	93.2
rs:WP_039758711	DNA topoisomerase I [Bartonella queenslandensis].	22.77	694	407	25	1	629	1	630	3e-16	93.2
rs:WP_044063101	DNA topoisomerase I [Prevotella sp. oral taxon 473].	27.31	487	278	20	72	525	46	489	3e-16	93.2
rs:WP_039496180	DNA topoisomerase I [Pectobacterium carotovorum].	23.91	598	374	21	74	633	81	635	3e-16	93.2
rs:WP_017793097	DNA topoisomerase I [Leucobacter salsicius].	23.72	586	344	18	2	530	6	545	3e-16	93.2
rs:WP_018392335	DNA topoisomerase I [Bacillus sp. 37MA].	23.48	558	361	21	105	629	82	606	3e-16	92.8
rs:WP_028449871	DNA topoisomerase I [Chitinibacter tainanensis].	24.00	600	379	22	74	630	51	616	3e-16	93.2
rs:WP_035012822	DNA topoisomerase I [Catenovulum agarivorans].	22.40	643	412	19	73	673	81	678	3e-16	93.2
rs:WP_024675102	DNA topoisomerase I [Pseudomonas syringae].	23.48	592	382	20	74	633	87	639	3e-16	93.2
rs:WP_017129593	topoisomerase I [Pseudomonas gingeri].	23.69	477	302	15	186	633	196	639	3e-16	93.2
rs:WP_028619418	DNA topoisomerase I [Pseudomonas sp. 2-92(2010)].	23.80	479	297	14	187	633	197	639	3e-16	93.2
rs:WP_020294130	DNA topoisomerase I [Pseudomonas sp. CFII64].	23.99	596	374	22	74	633	87	639	3e-16	93.2
rs:WP_038098345	hypothetical protein, partial [Thioalkalivibrio sp. HK1].	23.01	552	339	18	32	534	18	532	3e-16	93.2
tr:R9KZ71_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.84	562	354	19	90	616	73	595	3e-16	92.8
rs:WP_047275656	DNA topoisomerase I [Pseudomonas fluorescens].	23.95	476	302	14	186	633	196	639	3e-16	93.2
rs:WP_034767886	DNA topoisomerase I [Hyphomonas sp. CY54-11-8].	24.78	686	399	33	1	629	1	626	3e-16	93.2
rs:WP_006669315	DNA topoisomerase I [Arthrospira maxima].	23.36	578	340	21	3	530	4	528	3e-16	93.2
rs:WP_032818446	DNA topoisomerase I [Oenococcus oeni].	23.58	581	372	21	83	630	66	607	3e-16	92.8
rs:WP_010355625	DNA topoisomerase I subunit omega [Escherichia sp. TW09231].	23.19	595	389	20	73	633	74	634	3e-16	93.2
rs:WP_007944143	topoisomerase I [Pseudomonas sp. GM21].	23.58	475	303	14	187	633	197	639	3e-16	93.2
rs:WP_006803964	DNA topoisomerase I [Leptotrichia hofstadii].	24.31	617	374	20	2	589	4	556	3e-16	93.2
rs:WP_026680881	DNA topoisomerase I [Bacillus megaterium].	24.73	566	358	22	105	635	82	614	3e-16	92.8
tr:A0A060CQK6_HELPX	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:AIA98856.1};	24.90	486	327	14	75	536	46	517	3e-16	92.8
rs:WP_002984618	DNA topoisomerase I [Streptococcus pyogenes].	23.09	563	353	19	103	629	103	621	3e-16	92.8
tr:F8DPI6_LACRS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.78	577	355	25	90	629	26	560	3e-16	92.8
tr:V8CFY5_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.59	568	367	15	76	615	53	581	3e-16	93.2
rs:WP_039310266	DNA topoisomerase I [Pectobacterium atrosepticum].	23.52	625	363	23	57	633	78	635	3e-16	93.2
tr:F1ZA60_9SPHN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.49	619	414	20	55	629	22	612	3e-16	93.2
rs:WP_013615831	DNA topoisomerase I [Deinococcus proteolyticus].	24.31	543	322	20	77	572	66	566	3e-16	92.8
rs:WP_045859928	DNA topoisomerase I [Alteromonadaceae bacterium Bs12].	24.59	606	371	24	65	629	80	640	3e-16	93.2
tr:U1CM27_ENTGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	22.96	479	303	13	187	633	64	508	3e-16	93.2
rs:WP_025159788	DNA topoisomerase I [Serratia marcescens].	23.68	608	363	20	74	633	80	634	3e-16	93.2
sp:TOP1_ZYMMO	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	23.16	678	413	26	1	629	1	619	3e-16	93.6
rs:WP_042189457	DNA topoisomerase I [Paenibacillus sp. FSL H7-0737].	23.85	587	376	23	88	636	62	615	3e-16	92.8
rs:WP_027029180	DNA topoisomerase I [Mesorhizobium loti].	22.97	701	401	26	1	630	1	633	3e-16	93.2
rs:WP_015090086	DNA topoisomerase I [Bdellovibrio bacteriovorus].	24.20	591	324	23	1	530	11	538	3e-16	93.2
rs:WP_004207248	DNA topoisomerase I [Sphingobium yanoikuyae].	21.15	676	424	22	1	629	1	614	3e-16	93.2
rs:WP_019858383	DNA topoisomerase I [Mesorhizobium loti].	22.97	701	401	25	1	630	1	633	3e-16	93.2
rs:WP_010909698	DNA topoisomerase I [Mesorhizobium loti].	22.97	701	401	25	1	630	1	633	3e-16	93.2
rs:WP_022702956	DNA topoisomerase I [Pseudorhodobacter ferrugineus].	22.43	682	445	20	1	631	1	649	3e-16	93.2
rs:WP_016553640	DNA topoisomerase I subunit omega [Rhizobium grahamii].	21.73	695	420	26	1	630	1	636	3e-16	93.2
rs:WP_010491323	DNA topoisomerase I [Paenibacillus elgii].	24.16	592	371	22	88	636	62	618	3e-16	92.8
rs:WP_047338534	DNA topoisomerase I [Enterococcus cecorum].	25.13	569	355	26	103	635	81	614	3e-16	92.8
rs:WP_033775410	hypothetical protein [Helicobacter pylori].	25.00	616	371	25	41	611	28	597	3e-16	93.2
rs:WP_021273797	DNA topoisomerase I [Bacteriovorax sp. Seq25_V].	24.77	553	331	21	83	587	126	641	3e-16	93.2
rs:WP_015328611	DNA topoisomerase I [Gloeocapsa sp. PCC 7428].	23.90	657	396	20	3	614	4	601	3e-16	92.8
rs:WP_025858485	DNA topoisomerase I [Pseudomonas sp. CHM02].	23.63	474	306	13	186	633	196	639	3e-16	93.2
rs:WP_025237092	DNA topoisomerase I [Escherichia albertii].	23.40	594	389	20	73	633	74	634	3e-16	93.2
rs:WP_033608284	DNA topoisomerase I, partial [Helicobacter pylori].	25.00	492	319	14	75	536	46	517	3e-16	92.8
rs:WP_044462178	DNA topoisomerase I [Pseudomonas sp. MRSN12121].	22.78	474	310	12	186	633	196	639	3e-16	93.2
rs:XP_008475039	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-beta-1-like [Diaphorina citri].	22.19	676	441	21	3	630	5	643	3e-16	93.2
rs:XP_009765589	PREDICTED: DNA topoisomerase 3-beta isoform X3 [Nicotiana sylvestris].	21.88	553	376	16	105	631	55	577	3e-16	93.2
rs:WP_026972497	DNA topoisomerase I [Aliagarivorans marinus].	23.97	609	367	23	72	633	82	641	3e-16	93.2
tr:J0RMT3_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.24	531	327	20	3	521	12	484	3e-16	93.2
rs:WP_028946757	DNA topoisomerase I [Synechocystis sp. PCC 6714].	23.83	621	373	21	2	572	3	573	3e-16	93.2
rs:WP_039129857	DNA topoisomerase I [Leisingera sp. ANG-Vp].	22.19	703	414	24	1	630	1	643	3e-16	93.2
rs:WP_045590468	DNA topoisomerase I [Vibrio vulnificus].	24.32	621	373	23	60	633	69	639	3e-16	93.2
rs:WP_033634748	DNA topoisomerase I [Serratia marcescens].	23.68	608	363	20	74	633	80	634	3e-16	93.2
rs:WP_044532637	DNA topoisomerase I, partial [Bacteroides intestinalis].	23.28	597	373	19	3	580	5	535	3e-16	92.4
rs:WP_040001828	DNA topoisomerase I [[Eubacterium] infirmum].	25.13	593	345	24	90	635	61	601	3e-16	92.8
rs:WP_025919080	DNA topoisomerase I [Pectobacterium wasabiae].	23.68	608	363	21	74	633	81	635	3e-16	93.2
rs:WP_022633521	DNA topoisomerase [Dickeya solani].	22.38	648	401	22	75	673	81	675	3e-16	93.2
rs:WP_021101011	DNA topoisomerase I [Litoreibacter arenae].	22.17	681	420	24	1	629	1	623	3e-16	93.2
rs:WP_036093842	DNA topoisomerase I [Listeria newyorkensis].	22.68	560	376	20	105	635	82	613	3e-16	92.8
rs:WP_017499589	DNA topoisomerase I [alpha proteobacterium LLX12A].	21.15	676	424	22	1	629	1	614	3e-16	93.2
rs:WP_010180521	topoisomerase I [Glaciecola sp. HTCC2999].	24.42	606	381	23	65	629	75	644	3e-16	93.2
rs:WP_037011197	DNA topoisomerase I [Pseudomonas lutea].	23.15	596	379	20	74	633	86	638	3e-16	93.2
rs:WP_038399844	DNA topoisomerase I [Yersinia pseudotuberculosis].	22.98	657	386	22	74	673	86	679	4e-16	93.2
rs:WP_040098544	DNA topoisomerase I [Aeromonas australiensis].	23.93	606	364	23	75	633	82	637	4e-16	93.2
rs:WP_038647025	DNA topoisomerase I [Mesorhizobium huakuii].	22.97	701	401	25	1	630	1	633	4e-16	93.2
rs:WP_021229836	topoisomerase I [Aeromonas veronii].	23.93	606	364	23	75	633	82	637	4e-16	93.2
rs:WP_019106970	DNA topoisomerase I [Peptoniphilus senegalensis].	24.00	625	397	24	90	679	67	648	4e-16	92.8
rs:WP_021359105	DNA topoisomerase I [Peptoclostridium difficile].	24.50	653	383	25	3	616	5	586	4e-16	92.8
rs:WP_008368407	topoisomerase I [Pseudomonas sp. M47T1].	22.98	483	298	14	186	633	195	638	4e-16	93.2
rs:WP_011847016	topoisomerase I [Shewanella baltica].	23.96	480	294	17	187	631	198	641	4e-16	93.2
rs:WP_021904113	DNA topoisomerase [Clostridium sp. CAG:81].	23.89	628	380	24	90	671	67	642	4e-16	92.8
rs:WP_004930691	MULTISPECIES: DNA topoisomerase I subunit omega [Serratia].	23.68	608	363	20	74	633	80	634	4e-16	93.2
rs:WP_022610573	DNA topoisomerase 1 [Vibrio nigripulchritudo].	25.39	508	301	16	163	633	174	640	4e-16	93.2
rs:WP_030127251	DNA topoisomerase I [Streptococcus pyogenes].	22.86	560	358	19	103	629	103	621	4e-16	92.8
rs:XP_006572532	PREDICTED: DNA topoisomerase 3-like, partial [Apis mellifera].	24.12	456	282	15	188	614	33	453	4e-16	91.7
rs:WP_022740904	DNA topoisomerase I [Lachnospiraceae bacterium COE1].	23.86	570	344	20	90	616	67	589	4e-16	92.8
rs:WP_019034424	DNA topoisomerase I [Peptoniphilus lacrimalis].	22.49	716	441	28	3	678	5	646	4e-16	92.8
rs:WP_005612814	DNA topoisomerase I [Ruminococcus lactaris].	22.88	555	368	17	90	616	67	589	4e-16	92.8
tr:B3C7S7_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.94	619	395	19	3	601	15	571	4e-16	93.2
rs:WP_038823909	DNA topoisomerase I [Yersinia pseudotuberculosis].	22.80	649	397	20	74	673	86	679	4e-16	93.2
tr:A0A068UAG3_COFCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.41	645	381	27	3	585	20	613	4e-16	93.2
rs:WP_046230703	DNA topoisomerase I [Paenibacillus algorifonticola].	24.56	574	356	25	103	636	80	616	4e-16	92.8
rs:WP_038881773	DNA topoisomerase I [Serratia marcescens].	23.68	608	363	20	74	633	80	634	4e-16	93.2
rs:WP_022592886	DNA topoisomerase 1 [Vibrio nigripulchritudo].	25.39	508	301	16	163	633	174	640	4e-16	93.2
tr:G9A4M7_RHIFH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.80	693	415	28	1	630	3	638	4e-16	93.2
rs:WP_008844703	DNA topoisomerase I [Aliiglaciecola lipolytica].	23.33	690	409	24	3	629	5	637	4e-16	93.2
rs:WP_002462101	topoisomerase I [Escherichia albertii].	23.40	594	389	20	73	633	74	634	4e-16	93.2
rs:WP_010332637	DNA topoisomerase I subunit omega [Escherichia albertii].	23.40	594	389	20	73	633	74	634	4e-16	93.2
rs:WP_037236659	DNA topoisomerase I [Rhodomicrobium udaipurense].	22.74	642	394	23	55	630	27	632	4e-16	93.2
rs:WP_019741898	topoisomerase I, partial [Pseudomonas savastanoi].	24.00	475	301	14	187	633	63	505	4e-16	92.8
rs:WP_036706889	DNA topoisomerase I [Paenibacillus sp. P1XP2].	23.63	584	381	22	88	636	62	615	4e-16	92.8
rs:WP_021922657	GTP-sensing transcriptional pleiotropic repressor CodY [Roseburia inulinivorans CAG:15].	23.79	622	386	22	90	671	67	640	4e-16	92.8
rs:WP_022595650	DNA topoisomerase 1 [Vibrio nigripulchritudo].	25.39	508	301	16	163	633	174	640	4e-16	93.2
rs:WP_004406549	topoisomerase I [Vibrio nigripulchritudo].	25.39	508	301	16	163	633	174	640	4e-16	93.2
rs:WP_033615766	DNA topoisomerase I, partial [Helicobacter pylori].	24.85	487	326	15	75	536	46	517	4e-16	92.4
rs:WP_033071499	DNA topoisomerase I [Pectobacterium wasabiae].	23.68	608	363	21	74	633	81	635	4e-16	93.2
tr:G7YI59_CLOSI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAA52642.1};	23.34	497	315	19	96	560	5	467	4e-16	93.2
rs:WP_022374432	DNA topoisomerase [Firmicutes bacterium CAG:270].	24.78	581	338	21	83	616	60	588	4e-16	92.8
rs:WP_013701770	DNA topoisomerase I [Treponema succinifaciens].	23.12	666	408	25	3	630	19	618	4e-16	92.8
rs:WP_005061282	DNA topoisomerase I [Acinetobacter beijerinckii].	23.66	579	355	19	90	629	117	647	4e-16	93.2
rs:WP_025791346	DNA topoisomerase I [Prevotella histicola].	24.10	610	357	22	3	580	5	540	4e-16	92.8
rs:WP_025146647	DNA topoisomerase I [Sphingobacterium sp. H1ai].	25.39	516	333	15	77	578	54	531	4e-16	93.2
rs:WP_038939790	DNA topoisomerase I [Vibrio vulnificus].	24.32	621	373	23	60	633	69	639	4e-16	93.2
rs:WP_003449413	DNA topoisomerase I [Clostridium perfringens].	23.26	705	402	26	2	630	4	645	4e-16	92.8
rs:WP_013499649	DNA topoisomerase I [Ruminococcus albus].	25.44	574	349	21	97	629	73	608	4e-16	92.8
rs:WP_005619258	DNA topoisomerase I [Pseudomonas avellanae].	23.31	592	383	20	74	633	87	639	4e-16	93.2
rs:WP_033191919	DNA topoisomerase I [Fervidobacterium islandicum].	22.84	670	423	20	2	642	39	643	4e-16	92.8
rs:WP_017421991	topoisomerase I [Vibrio vulnificus].	24.32	621	373	23	60	633	69	639	4e-16	93.2
rs:WP_008497955	DNA topoisomerase I [Planococcus halocryophilus].	22.95	562	363	19	103	630	80	605	4e-16	92.8
rs:WP_041409512	DNA topoisomerase I [Sinorhizobium fredii].	22.80	693	415	28	1	630	1	636	4e-16	93.2
tr:A0A078CQI8_BRANA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.55	479	324	13	125	586	5	453	4e-16	92.8
rs:WP_016215054	DNA topoisomerase I [Eubacterium sp. 14-2].	23.71	561	356	17	90	616	67	589	4e-16	92.8
tr:Q6XZ01_SPIKU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.72	635	395	23	38	643	24	604	4e-16	92.8
rs:WP_033647571	DNA topoisomerase I [Serratia marcescens].	23.68	608	363	20	74	633	80	634	4e-16	93.2
rs:WP_015834210	topoisomerase I [Photorhabdus asymbiotica].	22.28	534	318	16	187	673	190	673	4e-16	93.2
rs:WP_011417280	DNA topoisomerase I [Syntrophus aciditrophicus].	26.07	652	373	29	77	659	54	665	4e-16	92.8
rs:WP_007555187	DNA topoisomerase I [Dialister micraerophilus].	24.61	646	386	26	88	684	91	684	4e-16	92.8
rs:WP_046099430	DNA topoisomerase I [Staphylococcus carnosus].	23.45	597	384	20	90	649	67	627	4e-16	92.8
rs:WP_010340715	DNA topoisomerase I subunit omega [Escherichia albertii].	23.40	594	389	20	73	633	74	634	4e-16	93.2
rs:WP_044908119	DNA topoisomerase I [Lachnospiraceae bacterium MC2017].	23.76	564	357	18	90	616	67	594	4e-16	92.8
rs:WP_022392632	DNA topoisomerase [Bacteroides intestinalis CAG:315].	22.71	621	394	20	3	601	5	561	4e-16	92.8
rs:WP_008283969	DNA topoisomerase I [gamma proteobacterium HTCC5015].	23.10	567	348	21	3	533	5	519	4e-16	92.8
rs:WP_005362158	topoisomerase I [Aeromonas veronii].	23.93	606	364	23	75	633	82	637	4e-16	93.2
rs:WP_028068227	DNA topoisomerase I [Sphingobacterium thalpophilum].	23.42	521	328	17	31	526	18	492	4e-16	92.8
rs:WP_024026822	DNA topoisomerase I [Bacillus vireti].	23.49	562	370	21	105	635	82	614	4e-16	92.8
rs:WP_008111438	topoisomerase I [Pseudoalteromonas sp. BSi20311].	23.21	616	383	22	60	631	72	641	4e-16	93.2
rs:WP_024467401	DNA topoisomerase I [Treponema pedis].	25.10	486	300	18	163	618	164	615	4e-16	92.8
tr:U2U8X5_STRPY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.09	563	353	19	103	629	103	621	4e-16	92.8
rs:WP_039446508	DNA topoisomerase I [Vibrio vulnificus].	24.32	621	373	23	60	633	69	639	4e-16	93.2
rs:WP_014699936	DNA topoisomerase [Pectobacterium sp. SCC3193].	23.68	608	363	21	74	633	81	635	4e-16	92.8
rs:WP_003456255	DNA topoisomerase I [Pseudomonas pseudoalcaligenes].	22.32	587	395	14	74	633	85	637	4e-16	92.8
rs:WP_005334892	topoisomerase I [Aeromonas veronii].	23.93	606	364	23	75	633	82	637	4e-16	92.8
rs:WP_011568344	DNA topoisomerase I [Roseobacter denitrificans].	23.10	645	379	23	55	629	27	624	4e-16	92.8
rs:XP_009765588	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Nicotiana sylvestris].	21.88	553	376	16	105	631	65	587	4e-16	92.8
rs:WP_006081959	topoisomerase I [Shewanella baltica].	23.96	480	294	17	187	631	198	641	4e-16	92.8
rs:WP_015023560	DNA topoisomerase I [Psychroflexus torquis].	25.00	616	380	20	3	601	5	555	4e-16	92.8
rs:WP_024314695	MULTISPECIES: DNA topoisomerase I [Rhizobium].	22.64	658	407	25	38	630	16	636	4e-16	92.8
tr:W6RSU7_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.64	658	407	25	38	630	17	637	4e-16	92.8
rs:WP_019446731	topoisomerase I [Aeromonas sp. 159].	23.76	606	365	23	75	633	82	637	4e-16	92.8
rs:WP_031872486	DNA topoisomerase III, partial [Staphylococcus aureus].	35.67	171	97	5	3	168	4	166	4e-16	87.4
rs:WP_027962277	DNA topoisomerase I [Halomonas halodenitrificans].	24.95	485	285	17	186	633	201	643	4e-16	92.8
tr:C6M8I2_NEISI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.12	737	445	25	3	679	27	694	4e-16	92.8
rs:WP_014663959	MULTISPECIES: DNA topoisomerase I [Bacillus].	23.81	567	372	21	105	641	82	618	4e-16	92.8
rs:WP_013571404	topoisomerase I [Vibrio vulnificus].	24.32	621	373	23	60	633	69	639	4e-16	92.8
rs:XP_006814887	PREDICTED: DNA topoisomerase 3-beta-1 [Saccoglossus kowalevskii].	21.31	624	414	20	3	587	5	590	4e-16	92.8
rs:WP_004413385	topoisomerase I [Vibrio orientalis].	22.88	612	382	19	57	633	83	639	4e-16	92.8
rs:WP_020863038	DNA topoisomerase [Mycoplasma mycoides].	24.33	670	392	30	3	625	4	605	4e-16	92.4
rs:WP_021190581	hypothetical protein [Sphingobacterium sp. IITKGP-BTPF85].	31.40	207	135	7	475	676	1	205	4e-16	88.6
rs:WP_015214496	DNA topoisomerase I [Anabaena cylindrica].	25.52	580	347	22	79	610	59	601	4e-16	92.8
rs:WP_039489493	DNA topoisomerase I [Pectobacterium carotovorum].	23.91	598	374	21	74	633	81	635	4e-16	92.8
rs:WP_018993132	DNA topoisomerase I [Thioalkalivibrio sp. ARh4].	23.41	581	348	21	3	534	5	537	4e-16	92.8
rs:WP_029167774	DNA topoisomerase I [alpha proteobacterium SCGC AAA028-C07].	23.33	643	380	26	1	597	1	576	4e-16	92.8
rs:WP_036872957	DNA topoisomerase I [Prevotella buccalis].	23.92	627	381	24	3	602	5	562	4e-16	92.8
rs:WP_006086246	topoisomerase I [Shewanella baltica].	23.96	480	294	17	187	631	198	641	4e-16	92.8
rs:WP_022653837	DNA topoisomerase I [Aquaspirillum serpens].	22.54	621	400	21	55	630	29	613	4e-16	92.8
tr:L8TXQ7_AGGAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	23.48	477	303	13	187	633	7	451	4e-16	92.4
rs:XP_008958124	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Pan paniscus].	22.93	580	363	20	3	537	5	545	4e-16	92.8
tr:D4E5V9_SEROD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.95	618	349	24	74	633	10	564	4e-16	92.8
rs:WP_009312695	MULTISPECIES: DNA topoisomerase I [Neisseria].	22.69	670	424	23	70	679	37	672	4e-16	92.8
rs:WP_009204281	DNA topoisomerase I [Anaerostipes hadrus].	23.96	576	349	18	83	616	60	588	4e-16	92.8
rs:WP_044921041	DNA topoisomerase I [Anaerostipes hadrus].	23.96	576	349	18	83	616	60	588	4e-16	92.8
rs:WP_029727426	MULTISPECIES: DNA topoisomerase I [Sphingomonas].	23.01	678	420	24	1	629	1	625	4e-16	92.8
rs:WP_045628896	DNA topoisomerase I [Vibrio vulnificus].	24.29	601	361	21	77	633	89	639	4e-16	92.8
rs:WP_029775883	DNA topoisomerase I, partial [delta proteobacterium JGI 0000059-K16].	23.84	562	359	19	103	629	91	618	4e-16	92.8
rs:WP_044390317	DNA topoisomerase I [Pseudomonas syringae group genomosp. 3].	23.31	592	383	20	74	633	87	639	4e-16	92.8
rs:WP_022698960	DNA topoisomerase I [Maricaulis sp. JL2009].	23.28	683	402	27	1	629	1	615	4e-16	92.8
rs:WP_010449613	topoisomerase I [Pseudomonas fuscovaginae].	22.83	473	311	11	186	633	196	639	4e-16	92.8
rs:XP_009436163	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Pan troglodytes].	22.93	580	363	20	3	537	5	545	4e-16	92.8
tr:V6TTM7_GIAIN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESU40370.1};	24.53	636	394	31	1	574	1	612	4e-16	92.8
rs:WP_003690297	DNA topoisomerase I [Neisseria gonorrhoeae].	22.28	727	456	24	3	679	5	672	4e-16	92.8
rs:WP_009618233	DNA topoisomerase III [Pseudomonas sp. M1].	28.09	178	121	3	1	177	1	172	4e-16	87.8
rs:WP_029470217	DNA topoisomerase I [Clostridiales bacterium VE202-06].	24.25	565	348	18	90	616	67	589	4e-16	92.4
rs:WP_009557733	DNA topoisomerase I [Lactobacillus equicursoris].	22.75	567	349	18	90	616	99	616	4e-16	92.8
rs:WP_016266190	DNA topoisomerase I subunit omega [Yersinia enterocolitica].	23.52	608	364	19	74	633	86	640	4e-16	92.8
rs:WP_038825724	DNA topoisomerase I [Yersinia pseudotuberculosis].	22.80	649	397	20	74	673	86	679	4e-16	92.8
rs:WP_038141185	DNA topoisomerase I [Thiothrix lacustris].	25.05	491	311	16	76	534	53	518	4e-16	92.8
rs:WP_014454078	reverse gyrase [Caldisericum exile].	26.14	593	336	24	2	561	604	1127	4e-16	93.2
rs:WP_040275379	DNA topoisomerase I [Streptomonospora alba].	23.84	562	326	19	32	530	39	561	4e-16	92.8
rs:WP_021404437	DNA topoisomerase I [Peptoclostridium difficile].	24.65	718	416	32	3	675	5	642	4e-16	92.4
rs:WP_021952695	DNA topoisomerase [Eubacterium sp. CAG:161].	24.32	588	366	22	36	587	22	566	4e-16	92.4
rs:WP_012674102	DNA topoisomerase I [Sulfurihydrogenibium azorense].	25.20	504	324	17	55	537	28	499	4e-16	92.4
rs:WP_046516925	DNA topoisomerase I, partial [Cryomorphaceae bacterium ASP10-05a].	25.48	518	330	16	77	578	53	530	4e-16	92.4
rs:WP_045620526	DNA topoisomerase I [Vibrio vulnificus].	24.32	621	373	23	60	633	69	639	4e-16	92.8
rs:WP_018750904	DNA topoisomerase I [Paenibacillus sanguinis].	23.93	585	379	24	88	636	62	616	4e-16	92.4
tr:C0FQD4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.43	610	371	23	103	671	80	640	4e-16	92.8
rs:WP_009501685	DNA topoisomerase I subunit omega [Moraxella macacae].	23.02	643	404	22	75	670	120	718	4e-16	92.8
tr:W1DXM5_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	38.92	167	81	7	166	318	3	162	4e-16	88.6
rs:WP_008949746	topoisomerase I [Alishewanella jeotgali].	22.98	618	383	20	60	631	59	629	4e-16	92.8
rs:WP_021967574	DNA topoisomerase [Bacteroides intestinalis CAG:564].	22.94	619	395	19	3	601	5	561	4e-16	92.8
rs:WP_044154826	DNA topoisomerase I [Bacteroides intestinalis].	22.94	619	395	19	3	601	5	561	4e-16	92.8
rs:WP_029562680	DNA topoisomerase I, partial [Yersinia pestis].	22.97	653	391	21	74	673	74	667	4e-16	92.4
rs:WP_010295184	topoisomerase I [Pectobacterium carotovorum].	23.91	598	374	21	74	633	81	635	4e-16	92.8
rs:WP_022311841	DNA topoisomerase [Clostridium sp. CAG:91].	23.36	565	352	18	90	616	67	588	4e-16	92.4
rs:WP_026586954	DNA topoisomerase I [Bacillus sp. NSP9.1].	23.71	561	369	20	105	635	82	613	4e-16	92.4
rs:WP_040559679	DNA topoisomerase I [Prevotella histicola].	24.10	610	357	22	3	580	5	540	4e-16	92.8
rs:WP_011975123	DNA topoisomerase I [Sinorhizobium medicae].	22.69	692	417	27	1	630	21	656	4e-16	92.8
rs:XP_012671463	PREDICTED: DNA topoisomerase 3-beta-1 [Clupea harengus].	22.01	627	407	19	3	585	5	593	4e-16	92.8
rs:WP_010206361	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	28.63	234	157	6	256	479	61	294	4e-16	89.7
tr:U2KLI8_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.03	673	415	25	3	636	46	654	4e-16	92.8
rs:WP_035691735	DNA topoisomerase I [Flavobacterium sp. F52].	25.24	531	327	20	3	521	5	477	5e-16	92.8
rs:WP_039643387	DNA topoisomerase I [Geobacter sp. GSS01].	22.62	672	416	24	3	630	5	616	5e-16	92.8
rs:WP_012145384	MULTISPECIES: topoisomerase I [Serratia].	24.59	606	360	25	74	633	80	634	5e-16	92.8
rs:WP_021718458	DNA topoisomerase [Phascolarctobacterium sp. CAG:207].	23.45	563	355	19	90	616	67	589	5e-16	92.4
rs:WP_012963136	DNA topoisomerase I [Hydrogenobacter thermophilus].	35.44	158	102	0	157	314	129	286	5e-16	92.0
rs:WP_013796385	topoisomerase I [Marinomonas posidonica].	23.11	649	396	24	73	673	87	680	5e-16	92.8
rs:WP_032839013	DNA topoisomerase I [Bacteroides finegoldii].	24.08	544	332	18	3	526	5	487	5e-16	92.8
rs:WP_046900255	DNA topoisomerase I [Gluconobacter oxydans].	22.56	585	364	21	103	629	79	632	5e-16	92.8
tr:W8V6A2_YEREN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.36	608	365	19	74	633	86	640	5e-16	92.8
rs:WP_025326222	DNA topoisomerase I [Aeromonas hydrophila].	23.76	606	365	22	75	633	82	637	5e-16	92.8
rs:WP_011080010	topoisomerase I [Vibrio vulnificus].	24.32	621	373	23	60	633	69	639	5e-16	92.8
rs:XP_008605361	hypothetical protein SDRG_01605 [Saprolegnia diclina VS20].	22.48	605	386	22	3	560	4	572	5e-16	92.8
rs:XP_001697150	hypothetical protein CHLREDRAFT_138607, partial [Chlamydomonas reinhardtii].	21.80	422	283	10	163	564	183	577	5e-16	92.4
rs:WP_028941161	DNA topoisomerase I [Pseudomonas umsongensis].	23.65	482	296	15	186	633	196	639	5e-16	92.8
rs:WP_016261235	topoisomerase I, partial [Yersinia pestis].	22.83	657	387	22	74	673	62	655	5e-16	92.8
rs:WP_039473052	DNA topoisomerase I [Pectobacterium carotovorum].	23.91	598	374	21	74	633	81	635	5e-16	92.8
rs:WP_018302176	DNA topoisomerase I [Wenxinia marina].	20.89	694	414	21	1	630	1	623	5e-16	92.8
tr:E6YZ97_BARSR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.44	691	409	31	1	629	1	633	5e-16	92.8
rs:WP_027900629	DNA topoisomerase I [Pseudomonas syringae].	22.84	591	387	19	74	633	86	638	5e-16	92.8
rs:WP_026490871	DNA topoisomerase I [Butyrivibrio sp. XPD2002].	24.06	557	360	19	90	616	70	593	5e-16	92.4
rs:WP_037519864	DNA topoisomerase I [Sphingobium yanoikuyae].	21.15	676	424	22	1	629	1	614	5e-16	92.8
rs:WP_012991133	reverse gyrase [Thermocrinis albus].	24.06	557	336	22	3	536	593	1085	5e-16	92.8
rs:WP_028505977	DNA topoisomerase I [Ruminococcus sp. FC2018].	23.81	567	355	20	103	629	79	608	5e-16	92.4
rs:WP_037358086	DNA topoisomerase I [Selenomonas sp. oral taxon 892].	23.03	673	415	25	3	636	32	640	5e-16	92.4
tr:C9KRB4_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.08	544	332	18	3	526	15	497	5e-16	92.8
tr:I6H4J4_SHIFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.37	215	143	7	286	493	1	211	5e-16	88.6
rs:WP_042015614	DNA topoisomerase I [Aeromonas caviae].	24.34	489	284	18	187	633	193	637	5e-16	92.8
rs:WP_004620068	DNA topoisomerase I [Caulobacter vibrioides].	21.90	685	420	24	1	629	1	626	5e-16	92.8
rs:WP_006880965	topoisomerase I [Vibrio brasiliensis].	25.00	500	313	14	163	633	173	639	5e-16	92.8
tr:G6AHM1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.10	610	357	22	3	580	11	546	5e-16	92.4
gpu:CP009314_105	DNA topoisomerase family protein [Bacillus anthracis str. Turkey32]	34.21	152	96	2	97	244	4	155	5e-16	87.4
rs:WP_047109379	DNA topoisomerase I [Vibrio vulnificus].	24.32	621	373	23	60	633	69	639	5e-16	92.8
rs:WP_016607025	topoisomerase I [Yersinia pestis].	22.83	657	387	22	74	673	53	646	5e-16	92.8
tr:A0A090CU18_PODAN	SubName: Full=Putative DNA topoisomerase 3 {ECO:0000313|EMBL:CDP32445.1};	23.27	563	344	20	3	520	5	524	5e-16	92.4
rs:XP_819023	DNA topoisomerase III [Trypanosoma cruzi strain CL Brener].	22.67	591	397	17	3	564	6	565	5e-16	92.8
tr:H1PLC7_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.13	593	345	24	90	635	84	624	5e-16	92.4
rs:WP_014407586	DNA topoisomerase I [Streptococcus pyogenes].	22.86	560	358	19	103	629	103	621	5e-16	92.4
rs:WP_045829100	DNA topoisomerase I [Luteibacter yeojuensis].	23.10	407	254	12	163	536	142	522	5e-16	92.8
rs:WP_029508370	DNA topoisomerase I [Lactobacillus suebicus].	24.48	576	365	23	88	629	80	619	5e-16	92.4
rs:WP_018355602	topoisomerase I [Pasteurella pneumotropica].	24.38	480	295	14	187	633	196	640	5e-16	92.8
tr:A0A0A5LUQ5_SERMA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.78	614	355	21	74	633	80	634	5e-16	92.8
rs:WP_009248640	DNA topoisomerase I [Lachnospiraceae bacterium 5_1_57FAA].	23.04	651	399	22	3	616	5	590	5e-16	92.4
rs:WP_038151022	DNA topoisomerase I [Vibrio furnissii].	23.59	619	369	18	57	633	85	641	5e-16	92.8
rs:WP_003670912	DNA topoisomerase I [Lactobacillus reuteri].	24.78	577	355	25	90	629	86	620	5e-16	92.4
rs:WP_002210622	DNA topoisomerase I [Yersinia pestis].	22.83	657	387	22	74	673	86	679	5e-16	92.8
rs:WP_039040523	MULTISPECIES: DNA topoisomerase I [Aeromonas].	24.34	489	284	18	187	633	193	637	5e-16	92.8
rs:WP_029206007	DNA topoisomerase I [alpha proteobacterium SCGC AAA487-M09].	23.28	640	384	24	1	597	1	576	5e-16	92.8
rs:WP_038928411	DNA topoisomerase I, partial [Yersinia pestis].	22.83	657	387	22	74	673	53	646	5e-16	92.8
rs:WP_027701667	DNA topoisomerase I [[Clostridium] mangenotii].	24.91	578	332	26	103	631	81	605	5e-16	92.4
tr:D5S2T3_PEPDI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.65	718	416	31	3	675	11	648	5e-16	92.4
rs:WP_024362045	MULTISPECIES: DNA topoisomerase I [Lysinibacillus].	23.20	556	369	18	103	629	80	606	5e-16	92.4
rs:XP_012768266	DNA topoisomerase, putative [Babesia bigemina].	21.28	686	429	27	3	620	7	649	5e-16	92.8
rs:WP_009413402	DNA topoisomerase I [Capnocytophaga sp. oral taxon 326].	25.52	533	323	16	3	521	5	477	5e-16	92.4
rs:WP_042870498	DNA topoisomerase I [Dickeya sp. NCPPB 569].	21.81	642	412	19	75	673	81	675	5e-16	92.8
rs:WP_016594614	topoisomerase I, partial [Yersinia pestis].	22.83	657	387	22	74	673	55	648	5e-16	92.8
rs:WP_016679553	topoisomerase I, partial [Yersinia pestis].	22.83	657	387	22	74	673	57	650	5e-16	92.8
rs:WP_021490989	topoisomerase I [Pseudomonas fluorescens].	23.79	475	304	14	186	633	196	639	5e-16	92.8
rs:WP_010275225	topoisomerase I [Pectobacterium carotovorum].	23.91	598	374	21	74	633	81	635	5e-16	92.8
tr:A0A024GSI2_9STRA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.53	617	389	21	4	573	1	575	5e-16	92.8
rs:WP_021848783	DNA topoisomerase [Bacteroides sp. CAG:598].	22.33	618	391	19	3	596	5	557	5e-16	92.4
rs:WP_006731013	DNA topoisomerase [Lactobacillus iners].	31.97	244	152	7	350	587	2	237	5e-16	88.6
rs:WP_004462358	DNA topoisomerase I [[Clostridium] symbiosum].	23.99	621	388	23	90	671	67	642	5e-16	92.4
rs:WP_046027573	DNA topoisomerase I [Vibrio vulnificus].	24.32	621	373	23	60	633	69	639	5e-16	92.8
rs:WP_035358326	DNA topoisomerase I [Acholeplasma equifetale].	24.24	561	342	21	100	629	79	587	5e-16	92.0
rs:WP_019090899	DNA topoisomerase I [Komagataeibacter europaeus].	21.46	685	428	28	3	630	4	635	5e-16	92.8
rs:WP_022994440	MULTISPECIES: topoisomerase I [Alcanivorax].	22.92	480	308	14	186	631	200	651	5e-16	92.8
rs:WP_014462334	topoisomerase I [Yersinia pestis].	22.83	657	387	22	74	673	22	615	5e-16	92.4
rs:WP_035857273	DNA topoisomerase I [Jeotgalicoccus marinus].	25.27	455	285	13	103	533	80	503	5e-16	92.4
rs:WP_035808132	DNA topoisomerase I [Jeotgalicoccus sp. 13MG44_air].	25.38	457	282	15	103	533	80	503	5e-16	92.4
rs:WP_021417477	DNA topoisomerase I, partial [Peptoclostridium difficile].	24.50	653	383	25	3	616	5	586	5e-16	92.0
rs:WP_003714143	DNA topoisomerase I [Neisseria lactamica].	22.80	737	440	27	3	679	5	672	5e-16	92.4
rs:WP_036191546	DNA topoisomerase I [Lysobacter concretionis].	22.98	470	302	13	103	536	80	525	5e-16	92.4
tr:I2NWJ9_NEISI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.69	670	424	23	70	679	59	694	5e-16	92.4
rs:WP_022153888	DNA topoisomerase [Firmicutes bacterium CAG:65].	23.39	560	358	16	90	616	67	588	5e-16	92.4
rs:WP_046384322	DNA topoisomerase I [Pseudomonas veronii].	23.63	474	306	13	186	633	196	639	5e-16	92.4
rs:WP_035253559	DNA topoisomerase I [Agrococcus lahaulensis].	23.59	496	309	13	77	528	67	536	5e-16	92.8
rs:WP_003666071	DNA topoisomerase I [Lactobacillus reuteri].	24.78	577	355	25	90	629	86	620	5e-16	92.4
rs:WP_031859989	DNA topoisomerase III, partial [Staphylococcus aureus].	25.00	316	221	6	311	620	1	306	5e-16	90.1
tr:S7J7E5_CHLPS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.55	497	312	19	77	534	47	519	5e-16	92.4
rs:WP_003694350	DNA topoisomerase I [Neisseria gonorrhoeae].	22.28	727	456	24	3	679	5	672	5e-16	92.4
rs:WP_003419396	DNA topoisomerase I [Peptoclostridium difficile].	24.65	718	416	31	3	675	5	642	5e-16	92.4
tr:E6Q4P1_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CBI02152.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI02152.1};	23.67	600	361	26	88	635	62	616	5e-16	92.4
rs:WP_024961841	DNA topoisomerase I, partial [Campylobacter ureolyticus].	24.86	531	304	18	158	627	24	520	5e-16	91.7
rs:XP_010579935	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Haliaeetus leucocephalus].	24.56	395	249	11	188	564	115	478	5e-16	92.4
rs:WP_034777177	DNA topoisomerase I [Exiguobacterium mexicanum].	22.69	661	423	25	3	630	5	610	5e-16	92.4
rs:WP_002880197	DNA topoisomerase I [Lactobacillus delbrueckii].	23.02	556	368	16	88	616	92	614	5e-16	92.4
rs:WP_040373193	DNA topoisomerase I [Bacillus psychrosaccharolyticus].	22.78	562	362	21	105	630	82	607	5e-16	92.4
rs:WP_043135968	DNA topoisomerase I [Aeromonas salmonicida].	23.64	605	367	21	75	633	82	637	5e-16	92.4
rs:WP_015638932	DNA topoisomerase I [Lactobacillus fermentum].	23.70	578	367	23	88	629	85	624	5e-16	92.4
rs:WP_021377880	DNA topoisomerase I [Peptoclostridium difficile].	24.79	718	415	31	3	675	5	642	5e-16	92.4
rs:WP_034449286	DNA topoisomerase I [Bartonella quintana].	22.78	698	405	27	1	629	1	633	6e-16	92.4
rs:WP_029967608	DNA topoisomerase I [Desulfonauticus sp. A7A].	25.47	632	367	24	83	667	60	634	6e-16	92.4
rs:WP_026666845	DNA topoisomerase I [Butyrivibrio sp. AE2005].	23.19	565	355	19	90	616	61	584	6e-16	92.0
rs:WP_003458449	DNA topoisomerase I [Clostridium perfringens].	23.26	705	402	26	2	630	4	645	6e-16	92.4
rs:WP_015060259	MULTISPECIES: DNA topoisomerase I [environmental samples].	25.15	485	319	14	67	537	51	505	6e-16	92.4
tr:K1SY50_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central domain protein {ECO:0000313|EMBL:EKC65527.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EKC65527.1}; Flags: Fragment;	28.63	241	154	4	348	575	3	238	6e-16	88.6
tr:A0A091PLN1_HALAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.56	395	249	11	188	564	112	475	6e-16	92.4
rs:WP_010252523	DNA topoisomerase I [Myroides injenensis].	25.24	527	332	17	3	521	5	477	6e-16	92.4
rs:XP_005391751	PREDICTED: DNA topoisomerase 3-beta-1 isoform X6 [Chinchilla lanigera].	24.52	416	262	12	188	585	115	496	6e-16	92.4
tr:T1D6H2_9ZZZZ	SubName: Full=DNA topoisomerase III beta {ECO:0000313|EMBL:EQD77880.1}; Flags: Fragment;	27.87	348	210	16	39	365	13	340	6e-16	89.7
rs:WP_003690118	DNA topoisomerase I [Neisseria gonorrhoeae].	22.28	727	456	24	3	679	5	672	6e-16	92.4
rs:WP_010360929	DNA topoisomerase I [Neisseria gonorrhoeae].	22.28	727	456	25	3	679	5	672	6e-16	92.4
rs:WP_009042977	topoisomerase I [Pseudomonas chlororaphis].	23.00	474	309	13	186	633	196	639	6e-16	92.4
rs:WP_007426411	DNA topoisomerase I [Oceaniovalibus guishaninsula].	22.94	510	305	17	77	534	52	525	6e-16	92.4
rs:WP_002719330	DNA topoisomerase I [Rhodobacter sphaeroides].	22.83	657	403	26	1	611	1	599	6e-16	92.4
rs:WP_016599731	topoisomerase I, partial [Yersinia pestis].	22.83	657	387	22	74	673	49	642	6e-16	92.4
rs:WP_033047184	hypothetical protein, partial [Clostridium botulinum].	27.23	235	159	4	161	395	45	267	6e-16	89.4
rs:WP_029916231	DNA topoisomerase I [Caulobacter sp. UNC358MFTsu5.1].	21.52	697	408	24	1	629	1	626	6e-16	92.4
rs:WP_042545939	DNA topoisomerase I [Yersinia aldovae].	22.66	653	393	21	74	673	86	679	6e-16	92.4
rs:WP_007096527	DNA topoisomerase I [Kordia algicida].	25.04	667	380	25	3	621	5	599	6e-16	92.4
rs:WP_044867927	DNA topoisomerase I, partial [Enterobacter cloacae].	24.48	478	305	14	76	533	82	523	6e-16	92.0
rs:XP_001655482	AAEL011603-PA [Aedes aegypti].	22.11	597	392	18	3	560	5	567	6e-16	92.4
rs:WP_039531544	DNA topoisomerase I [Pectobacterium carotovorum].	23.91	598	374	20	74	633	81	635	6e-16	92.4
rs:WP_026730539	DNA topoisomerase I [Flavobacterium denitrificans].	24.58	533	328	19	3	521	5	477	6e-16	92.4
rs:WP_040611837	DNA topoisomerase I [Roseomonas cervicalis].	23.68	604	385	23	81	630	57	638	6e-16	92.4
rs:WP_038498484	DNA topoisomerase I [Candidatus Baumannia cicadellinicola].	23.10	580	391	13	76	629	77	627	6e-16	92.4
rs:WP_005022546	DNA topoisomerase I [Helicobacter pullorum].	23.03	647	394	23	3	615	4	580	6e-16	92.4
rs:WP_026160957	DNA topoisomerase I [Sinorhizobium medicae].	22.69	692	417	27	1	630	1	636	6e-16	92.4
rs:WP_024311648	MULTISPECIES: DNA topoisomerase I [Sinorhizobium].	22.69	692	417	27	1	630	1	636	6e-16	92.4
rs:WP_032865663	DNA topoisomerase I, partial [Pseudomonas fluorescens].	23.68	473	305	13	187	633	53	495	6e-16	92.0
rs:XP_009922297	PREDICTED: DNA topoisomerase 3-beta-1, partial [Haliaeetus albicilla].	24.56	395	249	11	188	564	109	472	6e-16	92.4
rs:WP_011163504	DNA topoisomerase I [Bdellovibrio bacteriovorus].	24.32	592	322	23	1	530	11	538	6e-16	92.4
rs:WP_024766855	DNA topoisomerase I [Pseudomonas nitroreducens].	23.48	477	301	14	187	633	195	637	6e-16	92.4
rs:WP_003696216	DNA topoisomerase I [Neisseria gonorrhoeae].	22.42	727	455	24	3	679	5	672	6e-16	92.4
rs:WP_010474837	DNA topoisomerase I [Acaryochloris sp. CCMEE 5410].	24.96	573	345	21	79	610	58	586	6e-16	92.0
rs:WP_035268307	DNA topoisomerase I [Desulfitibacter alkalitolerans].	25.46	593	360	25	89	636	63	618	6e-16	92.0
rs:WP_008459965	DNA topoisomerase I [Lactobacillus equicursoris].	22.57	567	350	18	90	616	99	616	6e-16	92.0
rs:WP_010633259	MULTISPECIES: DNA topoisomerase I subunit omega [Aeromonas].	23.93	606	364	22	75	633	82	637	6e-16	92.4
rs:WP_046041393	DNA topoisomerase I [Pseudomonas fluorescens].	23.48	477	303	15	186	633	196	639	6e-16	92.4
rs:WP_008050053	topoisomerase I [Pseudomonas sp. GM74].	23.53	476	304	14	186	633	196	639	6e-16	92.4
rs:WP_007762029	DNA topoisomerase I [Bacteroides finegoldii].	24.08	544	332	18	3	526	5	487	6e-16	92.4
rs:WP_043556342	DNA topoisomerase I [Aeromonas bestiarum].	23.64	605	367	21	75	633	82	637	6e-16	92.4
rs:WP_016596023	topoisomerase I, partial [Yersinia pestis].	22.83	657	387	22	74	673	77	670	6e-16	92.4
rs:WP_007089913	DNA topoisomerase I [Thalassospira xiamenensis].	22.50	689	436	25	1	639	1	641	6e-16	92.4
rs:WP_027921688	DNA topoisomerase I [Pseudomonas sp. URMO17WK12:I12].	23.53	476	304	14	186	633	196	639	6e-16	92.4
rs:WP_013052041	topoisomerase I [Shewanella violacea].	23.17	600	374	20	74	631	88	642	6e-16	92.4
rs:WP_003481770	DNA topoisomerase I [Clostridium perfringens].	23.26	705	402	26	2	630	4	645	6e-16	92.0
rs:WP_043267321	DNA topoisomerase I [Pseudomonas sp. AAC].	23.01	478	304	13	186	633	195	638	6e-16	92.4
rs:WP_037506680	DNA topoisomerase I [Sphingobium yanoikuyae].	21.15	676	424	22	1	629	1	614	6e-16	92.4
rs:XP_007422502	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Python bivittatus].	22.46	610	386	21	3	564	5	575	6e-16	92.4
rs:WP_034559735	DNA topoisomerase I [Carnobacterium gallinarum].	24.39	574	365	21	90	629	68	606	6e-16	92.0
rs:WP_034662386	DNA topoisomerase I [Bacillus pumilus].	24.16	563	366	22	105	636	82	614	6e-16	92.0
rs:XP_001908297	hypothetical protein [Podospora anserina S mat+].	23.27	563	344	20	3	520	90	609	6e-16	92.0
rs:WP_033737372	DNA topoisomerase I [Helicobacter pylori].	25.15	485	327	15	75	536	46	517	6e-16	92.0
rs:WP_023275865	DNA topoisomerase I [Mucispirillum schaedleri].	23.87	683	414	25	1	640	5	624	6e-16	92.0
rs:WP_037012660	DNA topoisomerase I [Pseudomonas nitroreducens].	23.48	477	301	14	187	633	195	637	6e-16	92.4
rs:WP_044662359	DNA topoisomerase I [Sphingobium sp. YBL2].	20.72	671	433	20	1	629	1	614	6e-16	92.4
rs:WP_003403702	topoisomerase I [Pseudomonas syringae].	22.95	584	377	19	83	633	96	639	6e-16	92.4
sp:TOP1_BUCAP	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.12	481	311	15	74	537	74	517	6e-16	92.4
rs:WP_027208859	DNA topoisomerase I [Butyrivibrio hungatei].	23.19	565	355	19	90	616	61	584	6e-16	92.0
rs:WP_032009232	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	6e-16	92.4
tr:R9CB07_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOR24346.1};	28.85	253	151	6	360	611	21	245	6e-16	89.7
rs:WP_028143943	MULTISPECIES: DNA topoisomerase I [Bradyrhizobium].	23.44	687	414	24	1	630	1	632	6e-16	92.4
rs:WP_036015111	DNA topoisomerase I [Bradyrhizobium yuanmingense].	23.30	704	428	24	1	647	1	649	6e-16	92.4
rs:WP_034285550	DNA topoisomerase I [Bacillus sp. 72].	23.48	558	361	21	105	629	82	606	6e-16	92.0
rs:WP_024468694	DNA topoisomerase I [Treponema pedis].	25.10	486	300	18	163	618	164	615	6e-16	92.0
rs:WP_022460775	DNA topoisomerase [Alistipes putredinis CAG:67].	23.66	541	337	18	3	526	5	486	6e-16	92.0
rs:WP_004329382	DNA topoisomerase I [Alistipes putredinis].	23.66	541	337	18	3	526	5	486	6e-16	92.0
tr:E2NDW4_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.03	621	392	20	3	601	15	571	6e-16	92.0
tr:A0A0A8KSB6_LACFE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.53	579	361	26	88	629	85	624	6e-16	92.0
rs:WP_027146697	DNA topoisomerase I [Mesorhizobium sp. WSM3626].	23.11	701	400	26	1	630	1	633	6e-16	92.4
rs:WP_033910279	DNA topoisomerase I [Neisseria gonorrhoeae].	22.28	727	456	25	3	679	5	672	6e-16	92.0
rs:WP_023968539	topoisomerase I [Pseudomonas chlororaphis].	22.78	474	310	12	186	633	196	639	6e-16	92.4
rs:WP_038580619	DNA topoisomerase I [Pseudomonas chlororaphis].	22.78	474	310	12	186	633	196	639	6e-16	92.4
rs:WP_028682992	DNA topoisomerase I [Pseudomonas chlororaphis].	22.78	474	310	12	186	633	196	639	6e-16	92.4
rs:WP_010389785	topoisomerase I [Pseudoalteromonas undina].	22.88	612	390	22	60	631	72	641	6e-16	92.4
tr:T1DLK2_CROHD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.76	615	378	21	3	564	5	575	6e-16	92.4
rs:WP_027601459	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	24.21	475	300	15	187	633	195	637	6e-16	92.4
rs:WP_007921310	topoisomerase I [Pseudomonas sp. GM17].	22.78	474	310	12	186	633	196	639	6e-16	92.4
rs:WP_024777914	DNA topoisomerase I [Pseudomonas corrugata].	23.14	592	384	20	74	633	87	639	6e-16	92.4
rs:WP_033192706	reverse gyrase [Fervidobacterium islandicum].	23.99	567	325	25	3	536	597	1090	6e-16	92.4
rs:WP_027338680	DNA topoisomerase I [Halonatronum saccharophilum].	25.04	587	353	22	100	644	84	625	6e-16	92.0
rs:WP_041885017	DNA topoisomerase I [Pedobacter sp. NL19].	23.45	597	366	19	3	578	5	531	7e-16	92.4
rs:WP_013464804	topoisomerase I [Pseudoalteromonas sp. SM9913].	23.04	612	389	22	60	631	72	641	7e-16	92.4
rs:WP_045101789	DNA topoisomerase I [Aliivibrio wodanis].	24.54	603	370	21	77	639	89	646	7e-16	92.4
rs:WP_009047964	topoisomerase I [Pseudomonas chlororaphis].	22.78	474	310	12	186	633	196	639	7e-16	92.4
rs:WP_004390854	topoisomerase I [Yersinia kristensenii].	23.85	608	362	21	74	633	86	640	7e-16	92.4
rs:WP_045434151	hypothetical protein [bacterium UASB270].	25.43	586	340	25	103	630	80	626	7e-16	92.0
rs:WP_044286837	DNA topoisomerase I [Pseudomonas fluorescens].	23.79	475	304	14	186	633	196	639	7e-16	92.4
rs:WP_027155146	DNA topoisomerase I [Mesorhizobium sp. WSM2561].	23.12	705	395	28	1	630	1	633	7e-16	92.4
rs:WP_011116637	MULTISPECIES: DNA topoisomerase I [Helicobacter].	24.38	681	392	23	3	629	4	615	7e-16	92.0
rs:WP_011192446	topoisomerase I [Yersinia pseudotuberculosis].	22.83	657	387	22	74	673	86	679	7e-16	92.4
rs:WP_012044745	DNA topoisomerase I [Bradyrhizobium sp. BTAi1].	24.38	685	410	28	1	630	1	632	7e-16	92.4
rs:WP_005834274	MULTISPECIES: DNA topoisomerase I [Bacillales].	23.63	567	366	23	103	635	80	613	7e-16	92.0
rs:WP_042199154	DNA topoisomerase I [Paenibacillus sp. G4].	23.63	584	381	22	88	636	62	615	7e-16	92.0
tr:D4FWK7_BACNB	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.42	568	375	20	105	642	84	621	7e-16	92.0
rs:WP_013581109	DNA topoisomerase [Granulicella tundricola].	23.03	673	400	21	3	616	5	618	7e-16	92.4
rs:WP_003707115	DNA topoisomerase I [Neisseria lactamica].	22.70	727	453	26	3	679	5	672	7e-16	92.0
rs:WP_017288219	hypothetical protein [Leptolyngbya boryana].	22.95	623	398	17	77	653	67	653	7e-16	92.4
rs:WP_040343002	DNA topoisomerase III, partial [Bacillus nealsonii].	28.85	253	151	6	360	611	18	242	7e-16	89.7
rs:WP_007219376	DNA topoisomerase I [Bacteroides cellulosilyticus].	23.03	621	392	20	3	601	5	561	7e-16	92.0
tr:A0A077C4A4_9RICK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.50	685	414	27	1	630	1	630	7e-16	92.0
rs:WP_043945779	DNA topoisomerase III, partial [Carnobacterium sp. WN1359].	24.70	332	232	8	363	680	1	328	7e-16	89.4
rs:WP_009298158	MULTISPECIES: DNA topoisomerase I [Clostridiales].	23.99	621	388	23	90	671	67	642	7e-16	92.0
rs:WP_039655615	DNA topoisomerase I [Clostridium tyrobutyricum].	25.35	647	389	26	2	616	4	588	7e-16	92.0
rs:WP_025804224	DNA topoisomerase I [Pseudomonas chlororaphis].	22.78	474	310	12	186	633	196	639	7e-16	92.4
rs:WP_029724461	DNA topoisomerase I [Sphingomonas sp. JGI 0001003-D23].	23.01	678	420	24	1	629	1	625	7e-16	92.0
rs:WP_025831860	DNA topoisomerase I [Bacteroides stercorirosoris].	23.19	595	376	18	3	580	5	535	7e-16	92.0
rs:WP_024910790	DNA topoisomerase I [Serratia fonticola].	23.54	650	391	25	74	673	80	673	7e-16	92.0
rs:WP_032576958	DNA topoisomerase I, partial [Bacteroides fragilis].	26.36	330	226	7	163	480	3	327	7e-16	89.4
rs:WP_022468181	DNA topoisomerase [Acidaminococcus sp. CAG:917].	23.66	596	375	21	76	629	52	609	7e-16	92.0
rs:WP_020082763	hypothetical protein [gamma proteobacterium SCGC AAA076-P09].	23.27	563	370	18	75	616	87	608	7e-16	92.0
gp:AF042825_1	DNA topoisomerase I [Pyrococcus furiosus]	26.63	353	217	12	307	640	562	891	7e-16	92.4
gp:AF042825_1	DNA topoisomerase I [Pyrococcus furiosus]	30.73	179	117	3	140	312	17	194	2e-12	80.9
rs:WP_019084977	DNA topoisomerase I [Komagataeibacter europaeus].	21.46	685	428	28	3	630	4	635	7e-16	92.4
rs:WP_036039292	DNA topoisomerase I [Bradyrhizobium yuanmingense].	23.44	704	427	24	1	647	1	649	7e-16	92.4
tr:S7TBH8_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.05	603	369	22	76	630	60	621	7e-16	92.0
rs:WP_045766368	DNA topoisomerase I [Xanthomonas albilineans].	23.44	687	415	25	3	638	5	631	7e-16	92.0
rs:WP_024666109	DNA topoisomerase I [Pseudomonas syringae].	23.31	592	383	20	74	633	87	639	7e-16	92.0
rs:WP_012646645	DNA topoisomerase I [Geobacter daltonii].	23.99	642	391	24	76	658	53	656	7e-16	92.0
tr:B0N9B4_CLOSV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.89	651	400	22	3	616	19	604	7e-16	92.0
rs:WP_012963985	reverse gyrase [Hydrogenobacter thermophilus].	23.34	557	340	19	3	536	596	1088	7e-16	92.4
rs:WP_020965885	DNA topoisomerase I [Treponema pedis].	24.95	485	302	18	163	618	164	615	7e-16	92.0
rs:WP_021015979	DNA topoisomerase I [Serratia sp. ATCC 39006].	22.87	656	408	22	57	673	77	673	7e-16	92.0
rs:WP_017393949	MULTISPECIES: topoisomerase I [Acinetobacter calcoaceticus/baumannii complex].	23.66	596	366	20	75	629	99	646	7e-16	92.0
rs:WP_022369374	DNA topoisomerase [Firmicutes bacterium CAG:882].	24.18	546	346	18	103	616	80	589	7e-16	92.0
rs:WP_005253290	DNA topoisomerase I [Acinetobacter sp. CIP 102136].	25.10	486	318	15	67	537	51	505	7e-16	92.0
rs:WP_010052918	DNA topoisomerase I [Carnobacterium maltaromaticum].	23.74	577	365	20	90	629	68	606	7e-16	92.0
rs:WP_005236830	DNA topoisomerase I [Enterococcus casseliflavus].	25.17	572	351	24	103	635	81	614	7e-16	92.0
rs:WP_043972525	DNA topoisomerase I [Novosphingobium sp. P6W].	21.30	723	469	25	1	680	1	666	7e-16	92.0
rs:WP_016340453	DNA topoisomerase I [Spiroplasma syrphidicola].	25.47	475	305	14	76	533	55	497	7e-16	91.7
tr:A0A075TZU3_9LACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.98	563	353	23	103	629	103	626	7e-16	92.0
rs:WP_043762019	DNA topoisomerase I [Aeromonas taiwanensis].	23.47	605	368	21	75	633	82	637	7e-16	92.0
rs:WP_011146662	topoisomerase I [Photorhabdus luminescens].	22.24	643	408	21	75	673	79	673	7e-16	92.0
rs:WP_032051078	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	7e-16	92.0
rs:WP_004458499	DNA topoisomerase I [Clostridium perfringens].	23.26	705	402	26	2	630	4	645	7e-16	92.0
rs:WP_010216795	topoisomerase I [Pseudomonas syringae group genomosp. 3].	23.31	592	383	20	74	633	87	639	7e-16	92.0
rs:WP_036025557	DNA topoisomerase I [Bradyrhizobium yuanmingense].	23.30	704	428	24	1	647	1	649	7e-16	92.0
rs:WP_003238559	DNA topoisomerase I [Bacillus subtilis].	23.72	565	375	20	105	641	82	618	7e-16	92.0
rs:WP_006925268	DNA topoisomerase I [Bartonella washoensis].	23.44	691	409	31	1	629	1	633	7e-16	92.0
rs:WP_010212072	MULTISPECIES: topoisomerase I [Pseudomonas].	23.79	475	304	14	186	633	196	639	7e-16	92.0
rs:WP_015730472	topoisomerase I [Pectobacterium wasabiae].	23.93	610	359	22	74	633	81	635	7e-16	92.0
rs:WP_003776900	DNA topoisomerase I [Alloiococcus otitis].	23.72	586	365	24	90	635	68	611	7e-16	92.0
rs:WP_008125031	DNA topoisomerase I [Prevotella timonensis].	23.31	592	374	19	3	578	5	532	7e-16	92.0
rs:WP_039409382	DNA topoisomerase I [Morococcus cerebrosus].	22.39	670	426	22	70	679	37	672	7e-16	92.0
tr:S4E3P0_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EPI11975.1};	31.28	179	109	4	3	172	4	177	7e-16	87.0
rs:WP_003062355	DNA topoisomerase I [Streptococcus dysgalactiae].	22.91	563	354	20	103	629	103	621	7e-16	92.0
rs:WP_027058799	DNA topoisomerase I [Mesorhizobium loti].	23.36	702	397	28	1	630	1	633	7e-16	92.0
rs:WP_009621355	DNA topoisomerase I [Pseudomonas sp. M1].	22.74	598	379	19	74	633	86	638	7e-16	92.0
rs:WP_039969181	DNA topoisomerase I [Veillonella dispar].	23.25	572	361	21	95	629	142	672	7e-16	92.0
rs:WP_029300089	DNA topoisomerase I [Pseudomonas fluorescens].	23.21	474	306	14	187	633	197	639	7e-16	92.0
rs:WP_036109494	MULTISPECIES: DNA topoisomerase I [Luteibacter].	24.39	410	245	13	163	536	142	522	7e-16	92.0
rs:WP_005765057	MULTISPECIES: topoisomerase I [Pseudomonas syringae group].	23.31	592	383	20	74	633	87	639	7e-16	92.0
tr:M5RDN2_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.32	514	329	21	154	636	132	616	7e-16	91.7
rs:WP_045770649	DNA topoisomerase I [Xanthomonas albilineans].	23.44	687	415	25	3	638	5	631	7e-16	92.0
rs:WP_038972448	DNA topoisomerase I [Bradyrhizobium sp. CCBAU 15635].	23.44	687	414	24	1	630	1	632	7e-16	92.0
rs:WP_014479776	DNA topoisomerase I [Bacillus subtilis].	23.42	568	375	20	105	642	82	619	7e-16	91.7
rs:WP_039104346	DNA topoisomerase I [Frischella perrara].	23.36	608	366	22	74	633	84	639	7e-16	92.0
rs:XP_006110599	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X4 [Pelodiscus sinensis].	23.62	398	249	13	188	564	115	478	7e-16	92.0
rs:WP_008898159	topoisomerase I [Rheinheimera sp. A13L].	23.24	598	375	21	75	631	75	629	7e-16	92.0
rs:WP_001970574	DNA topoisomerase, partial [Helicobacter pylori].	26.93	427	252	17	3	391	4	408	7e-16	90.9
rs:WP_012105105	topoisomerase I [Yersinia pseudotuberculosis].	22.83	657	387	22	74	673	86	679	7e-16	92.0
rs:WP_025383880	DNA topoisomerase I [Yersinia similis].	22.83	657	387	22	74	673	86	679	7e-16	92.0
rs:WP_018499586	DNA topoisomerase I [Leptotrichia wadei].	24.52	620	362	20	2	587	4	551	7e-16	92.0
tr:C4FQQ5_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.25	572	361	21	95	629	145	675	7e-16	92.0
sp:TOP1_PYRFU	RecName: Full=DNA topoisomerase 1; EC=5.99.1.2; AltName: Full=DNA topoisomerase I; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme; Contains: RecName: Full=Endonuclease PI-PfuI; EC=3.1.-.-; AltName: Full=Pfu topA intein;	26.63	353	217	12	307	640	688	1017	7e-16	92.4
sp:TOP1_PYRFU	RecName: Full=DNA topoisomerase 1; EC=5.99.1.2; AltName: Full=DNA topoisomerase I; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme; Contains: RecName: Full=Endonuclease PI-PfuI; EC=3.1.-.-; AltName: Full=Pfu topA intein;	26.44	329	216	8	1	312	1	320	1e-15	91.3
rs:WP_024575122	MULTISPECIES: DNA topoisomerase I [Afipia].	23.91	686	413	30	1	630	1	633	8e-16	92.0
rs:WP_034949065	DNA topoisomerase I [Erwinia oleae].	22.42	669	395	26	73	680	74	679	8e-16	92.0
rs:XP_975504	PREDICTED: DNA topoisomerase 3-beta-1 [Tribolium castaneum].	22.59	456	288	13	188	614	211	630	8e-16	92.0
rs:WP_022005878	DNA topoisomerase [Proteobacteria bacterium CAG:495].	22.79	689	405	25	1	629	1	622	8e-16	92.0
rs:WP_014639162	topoisomerase I [Escherichia coli].	23.32	596	387	21	73	633	74	634	8e-16	92.0
rs:WP_039589079	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	23.69	477	302	15	186	633	196	639	8e-16	92.0
rs:WP_044263883	DNA topoisomerase I [Candidatus Bacteroides timonensis].	23.03	621	392	20	3	601	5	561	8e-16	92.0
rs:WP_038052939	DNA topoisomerase I [Thioalkalivibrio sp. ALJ1].	22.67	569	350	20	3	534	5	520	8e-16	92.0
rs:WP_012766956	DNA topoisomerase I [Streptococcus dysgalactiae].	22.91	563	354	20	103	629	103	621	8e-16	91.7
tr:B0VL89_ACIBS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.66	596	366	20	75	629	99	646	8e-16	92.0
rs:XP_012269908	PREDICTED: DNA topoisomerase 3-beta-1 [Athalia rosae].	23.16	449	294	12	188	614	210	629	8e-16	92.0
rs:WP_013034676	DNA topoisomerase I [Nitrosococcus halophilus].	23.40	577	346	20	3	534	5	530	8e-16	92.0
rs:XP_006522060	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Mus musculus].	22.73	629	400	23	3	585	5	593	8e-16	91.7
rs:WP_022930930	DNA topoisomerase I [Treponema bryantii].	23.25	585	372	16	83	630	66	610	8e-16	91.7
rs:WP_022210546	MULTISPECIES: DNA topoisomerase [Bacteroides].	23.03	621	392	20	3	601	5	561	8e-16	92.0
rs:WP_033672103	DNA topoisomerase I [Bacillus gaemokensis].	23.21	560	373	20	105	635	82	613	8e-16	91.7
rs:WP_018127479	hypothetical protein [Balneola vulgaris].	25.24	626	369	21	3	577	4	581	8e-16	92.0
tr:A0A0D6Q8Q4_KOMXY	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAN99809.1};	22.12	529	343	18	84	571	60	560	8e-16	92.0
rs:WP_009905892	DNA topoisomerase [Peptoclostridium difficile].	39.37	127	62	5	1	119	1	120	8e-16	85.9
rs:WP_036927214	DNA topoisomerase I [Prevotella timonensis].	23.31	592	374	19	3	578	5	532	8e-16	92.0
rs:WP_039574026	DNA topoisomerase I [Sphingopyxis sp. Kp5.2].	22.29	664	431	22	1	629	1	614	8e-16	92.0
rs:WP_035500988	DNA topoisomerase I [Fusobacterium gonidiaformans].	26.11	586	345	19	3	561	6	530	8e-16	92.0
rs:WP_013739712	DNA topoisomerase I [Sphaerochaeta coccoides].	23.71	641	359	22	3	581	10	582	8e-16	92.0
rs:WP_026493829	DNA topoisomerase I [Butyrivibrio sp. XPD2006].	23.42	555	366	15	90	616	61	584	8e-16	91.7
rs:WP_046219671	DNA topoisomerase I [Photobacterium halotolerans].	23.74	594	375	18	76	633	88	639	8e-16	92.0
rs:WP_038528814	DNA topoisomerase I, partial [Weissella ceti].	23.98	563	353	23	103	629	103	626	8e-16	91.7
rs:WP_011104593	DNA topoisomerase I [Pseudomonas syringae group genomosp. 3].	23.31	592	383	20	74	633	87	639	8e-16	92.0
rs:WP_021971636	DNA topoisomerase [Bacteroides sp. CAG:1076].	23.46	618	393	19	3	604	5	558	8e-16	92.0
rs:WP_037478091	hypothetical protein, partial [Sphingobium sp. ba1].	21.69	724	463	28	1	680	1	664	8e-16	92.0
rs:XP_010320982	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Solanum lycopersicum].	24.08	652	381	26	3	592	12	611	8e-16	92.0
rs:WP_017367241	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.32	514	329	21	154	636	130	614	8e-16	91.7
rs:WP_011150808	topoisomerase I [Vibrio vulnificus].	23.79	618	380	21	60	633	69	639	8e-16	92.0
tr:W4PT77_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE22942.1};	30.39	204	140	2	85	287	15	217	8e-16	88.2
rs:WP_008587919	DNA topoisomerase I [Salimicrobium sp. MJ3].	23.85	566	363	21	105	635	83	615	8e-16	91.7
rs:WP_038950308	DNA topoisomerase I [Bradyrhizobium sp. CCBAU 15544].	23.44	687	414	24	1	630	1	632	8e-16	92.0
rs:WP_046215351	DNA topoisomerase I [Paenibacillus wulumuqiensis].	23.42	568	369	22	103	636	80	615	8e-16	91.7
tr:A0A024LSJ9_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.98	638	391	28	55	629	27	633	8e-16	92.0
rs:WP_046526653	DNA topoisomerase I [Bacillus sp. L_1B0_12].	24.32	514	329	21	154	636	130	614	8e-16	91.7
rs:WP_023198122	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	23.50	583	385	20	73	630	74	620	8e-16	91.7
rs:WP_037281219	DNA topoisomerase I [Rubellimicrobium mesophilum].	22.07	725	434	31	1	659	1	660	8e-16	92.0
rs:WP_039142858	DNA topoisomerase I [Lactobacillus fructivorans].	24.00	575	376	21	83	629	82	623	8e-16	91.7
rs:WP_024281948	DNA topoisomerase I [Algoriphagus marincola].	25.44	507	315	15	31	520	18	478	8e-16	92.0
rs:WP_000024265	DNA topoisomerase I subunit omega [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	8e-16	92.0
rs:WP_028040262	DNA topoisomerase I [Caulobacter sp. URHA0033].	21.09	697	411	24	1	629	1	626	8e-16	92.0
rs:WP_022976701	DNA topoisomerase I [Nevskia ramosa].	24.96	573	331	23	3	533	5	520	8e-16	92.0
rs:WP_017750624	DNA topoisomerase I [Clostridium tyrobutyricum].	25.35	647	389	26	2	616	4	588	8e-16	91.7
rs:WP_015955427	DNA topoisomerase I [Cyanothece sp. PCC 7424].	23.15	622	374	19	3	572	4	573	8e-16	92.0
rs:WP_022162924	DNA topoisomerase [Bacteroides sp. CAG:633].	24.95	473	295	15	76	526	53	487	8e-16	92.0
rs:WP_013182761	DNA topoisomerase I [Waddlia chondrophila].	24.10	610	355	23	82	630	59	621	8e-16	92.0
rs:WP_046026992	DNA topoisomerase I [Pseudomonas fluorescens].	23.53	476	304	14	186	633	196	639	8e-16	92.0
rs:XP_007973099	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Chlorocebus sabaeus].	25.30	415	260	14	188	585	151	532	8e-16	92.0
tr:D5RQA4_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.68	604	385	23	81	630	70	651	8e-16	92.0
rs:WP_037523331	DNA topoisomerase I [Sphingomonas wittichii].	22.07	734	449	28	1	680	1	665	8e-16	92.0
rs:WP_035513040	DNA topoisomerase, partial [Lactobacillus iners].	31.97	244	152	7	350	587	27	262	8e-16	88.6
tr:A0A087NAY7_9SPHN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.82	724	462	28	1	680	1	664	8e-16	92.0
tr:A0A066WP21_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.66	534	321	21	3	521	12	484	8e-16	92.0
rs:WP_044959040	DNA topoisomerase I [Shuttleworthia sp. MSX8B].	23.24	555	366	15	90	616	67	589	8e-16	91.7
rs:WP_032630415	DNA topoisomerase I [Pseudomonas syringae].	22.13	592	390	18	74	633	86	638	8e-16	92.0
rs:WP_043319020	DNA topoisomerase I [Pseudomonas sp. PI1].	23.38	479	301	14	186	633	195	638	8e-16	92.0
rs:WP_019218588	DNA topoisomerase I [Bartonella sp. R4(2010)].	23.90	728	429	31	1	666	1	665	8e-16	92.0
rs:WP_024850251	DNA topoisomerase I [Thiomicrospira kuenenii].	25.47	534	322	19	3	520	4	477	8e-16	92.0
rs:WP_017712774	hypothetical protein [Prochlorothrix hollandica].	23.84	625	373	16	3	566	4	586	8e-16	92.0
rs:WP_025435532	DNA topoisomerase I [Eubacterium acidaminophilum].	25.72	657	367	30	3	616	5	583	8e-16	91.7
rs:WP_023610295	DNA topoisomerase I [Streptococcus pyogenes].	22.68	560	359	19	103	629	103	621	8e-16	91.7
rs:WP_042177548	DNA topoisomerase I [Paenibacillus sp. FSL R7-0331].	23.63	584	381	22	88	636	62	615	8e-16	91.7
rs:WP_040370877	DNA topoisomerase I [Desulfovibrio alkalitolerans].	24.05	603	369	22	76	630	53	614	8e-16	91.7
rs:WP_031994209	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	8e-16	92.0
rs:WP_007251279	topoisomerase I [Pseudomonas syringae group genomosp. 3].	23.48	592	382	20	74	633	87	639	8e-16	92.0
rs:WP_026031461	DNA topoisomerase I [Sinorhizobium meliloti].	22.46	690	419	26	1	630	1	634	8e-16	92.0
tr:V5AV88_TRYCR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESS64730.1};	22.80	592	395	18	3	564	6	565	8e-16	92.0
rs:WP_031907700	DNA topoisomerase III, partial [Staphylococcus aureus].	27.48	353	208	11	351	676	17	348	8e-16	89.4
rs:WP_014500347	DNA topoisomerase I [Zymomonas mobilis].	23.01	678	414	26	1	629	1	619	8e-16	92.0
rs:WP_000655392	DNA topoisomerase I [Helicobacter pylori].	24.44	491	323	13	75	536	46	517	8e-16	91.7
tr:A0A0C1GX80_9NEIS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.39	670	426	22	70	679	59	694	8e-16	91.7
tr:E5BEB8_9FUSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.11	586	345	19	3	561	12	536	8e-16	91.7
rs:WP_005968653	topoisomerase I [Pectobacterium wasabiae].	23.42	602	372	21	74	633	81	635	8e-16	92.0
rs:WP_009757221	DNA topoisomerase I [Lachnospiraceae bacterium 2_1_46FAA].	23.04	560	361	16	90	616	67	589	8e-16	91.7
rs:WP_012917334	DNA topoisomerase I [Xanthomonas albilineans].	23.44	687	415	25	3	638	5	631	8e-16	92.0
rs:WP_033848486	MULTISPECIES: DNA topoisomerase I [Yersinia].	22.83	657	387	22	74	673	86	679	8e-16	92.0
tr:W1FGI9_ENTCL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	23.24	469	302	15	193	633	1	439	8e-16	91.7
rs:WP_019408699	topoisomerase I [Pseudomonas psychrophila].	24.00	475	301	14	187	633	197	639	9e-16	92.0
rs:WP_020875156	DNA topoisomerase I [Desulfococcus multivorans].	24.04	599	368	22	76	630	57	612	9e-16	91.7
tr:U5SEA8_9LACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AGY82458.1};	24.70	332	232	8	363	680	27	354	9e-16	89.4
rs:WP_000024268	topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	9e-16	92.0
rs:WP_006959504	DNA topoisomerase I [Sphingobium japonicum].	22.02	672	423	24	1	629	1	614	9e-16	92.0
rs:WP_024857897	DNA topoisomerase I [Ruminococcus albus].	25.09	574	351	21	97	629	73	608	9e-16	91.7
rs:WP_044857889	DNA topoisomerase I, partial [Enterobacter cloacae].	24.63	471	313	14	76	533	82	523	9e-16	90.9
rs:WP_008344821	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.32	514	329	21	154	636	130	614	9e-16	91.7
rs:WP_045651823	DNA topoisomerase I [Gammaproteobacteria bacterium BRH_c0].	23.16	652	397	21	74	677	91	686	9e-16	92.0
rs:WP_035675539	DNA topoisomerase I [Flavobacterium frigidarium].	25.75	536	318	21	3	521	5	477	9e-16	92.0
rs:WP_021584790	topoisomerase repeat protein, partial [Prevotella pleuritidis].	31.65	218	138	7	459	673	2	211	9e-16	87.8
rs:WP_013895222	DNA topoisomerase I [Mesorhizobium opportunistum].	22.14	700	408	23	1	630	1	633	9e-16	92.0
rs:WP_019254030	DNA topoisomerase I [Lactobacillus reuteri].	26.04	576	349	28	90	629	86	620	9e-16	91.7
rs:WP_025487140	DNA topoisomerase I [Clostridiales bacterium VE202-28].	23.30	575	346	19	90	616	67	594	9e-16	91.7
rs:WP_023593058	DNA topoisomerase I [Zymomonas mobilis].	23.01	678	414	26	1	629	1	619	9e-16	92.0
rs:WP_017337559	topoisomerase I [Pseudomonas fluorescens].	23.69	477	302	15	186	633	196	639	9e-16	92.0
rs:WP_033627266	DNA topoisomerase, partial [Enterococcus faecium].	29.58	213	134	6	470	667	2	213	9e-16	87.8
rs:WP_042024775	DNA topoisomerase I [Aeromonas enteropelogenes].	23.60	606	366	22	75	633	82	637	9e-16	92.0
rs:WP_025837075	DNA topoisomerase I [Prevotella scopos].	24.29	601	363	22	3	578	5	538	9e-16	91.7
rs:WP_005407451	DNA topoisomerase I [Acinetobacter radioresistens].	24.79	484	322	14	67	537	51	505	9e-16	91.7
rs:XP_010700529	DNA topoisomerase III, putative [Leishmania panamensis].	21.97	610	393	19	3	571	6	573	9e-16	92.0
rs:WP_011858247	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	9	556	9e-16	91.7
rs:WP_003703296	DNA topoisomerase I [Neisseria gonorrhoeae].	22.15	727	457	25	3	679	5	672	9e-16	91.7
rs:WP_035700740	DNA topoisomerase I [Bacillus altitudinis].	24.32	514	329	21	154	636	130	614	9e-16	91.7
rs:WP_024295678	MULTISPECIES: DNA topoisomerase I [Lachnoclostridium].	24.56	562	352	19	90	616	67	591	9e-16	91.7
rs:XP_011780214	DNA topoisomerase III, putative [Trypanosoma brucei gambiense DAL972].	21.38	683	417	24	3	616	5	636	9e-16	92.0
rs:WP_002132868	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	9e-16	92.0
rs:WP_039909173	DNA topoisomerase I [[Clostridium] scindens].	22.89	651	400	22	3	616	5	590	9e-16	91.7
rs:WP_019196747	DNA topoisomerase I [Afipia birgiae].	24.09	685	411	30	1	629	1	632	9e-16	92.0
rs:WP_008716355	DNA topoisomerase I [Clostridiales bacterium 1_7_47FAA].	23.30	575	346	19	90	616	67	594	9e-16	91.7
rs:WP_035658494	DNA topoisomerase I [Flavobacterium sp. EM1321].	25.66	534	321	21	3	521	5	477	9e-16	91.7
rs:WP_035458482	DNA topoisomerase I [Alcanivorax sp. 97CO-5].	22.35	595	385	19	76	631	93	649	9e-16	92.0
rs:WP_036480850	DNA topoisomerase I [Nitratireductor basaltis].	21.53	692	422	24	1	630	1	633	9e-16	91.7
sp:TOP3B_MOUSE	RecName: Full=DNA topoisomerase 3-beta-1; EC=5.99.1.2; AltName: Full=DNA topoisomerase III beta-1;	23.05	629	398	24	3	585	5	593	9e-16	91.7
rs:WP_018596075	DNA topoisomerase I [Blautia producta].	24.25	565	348	18	90	616	67	589	9e-16	91.7
rs:WP_032017180	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	9e-16	91.7
rs:WP_039232154	DNA topoisomerase I [Bacillus thermotolerans].	23.34	557	367	18	105	629	82	610	9e-16	91.7
rs:WP_046809665	DNA topoisomerase I [Pseudomonas psychrophila].	22.43	593	387	17	74	633	87	639	9e-16	91.7
rs:WP_000024270	DNA topoisomerase I subunit omega [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	9e-16	91.7
rs:WP_036000431	DNA topoisomerase I, partial [Leptolyngbya sp. JSC-1].	23.37	569	351	16	3	530	4	528	9e-16	91.7
rs:WP_021743820	DNA topoisomerase I [Leptotrichia sp. oral taxon 879].	23.90	615	379	19	2	589	4	556	9e-16	91.7
tr:F3GKN5_PSESJ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGH47638.1}; Flags: Fragment;	30.67	163	108	2	65	223	1	162	9e-16	87.0
rs:WP_001973712	DNA topoisomerase [Helicobacter pylori].	24.95	485	328	15	75	536	46	517	9e-16	91.7
rs:WP_000024269	topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	9e-16	91.7
rs:WP_028659797	DNA topoisomerase I [Nocardioides insulae].	24.12	655	346	31	2	577	4	586	9e-16	91.7
rs:WP_008484103	topoisomerase I [Gallaecimonas xiamenensis].	24.37	677	400	29	3	633	5	615	9e-16	91.7
tr:A0A091RQY5_NESNO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.74	563	365	18	36	564	26	552	9e-16	91.7
rs:WP_046447381	DNA topoisomerase I, partial [Carnobacterium sp. N15.MGS-251].	23.36	565	352	18	90	616	67	588	9e-16	91.3
rs:WP_004883804	DNA topoisomerase I subunit omega [Pseudomonas viridiflava].	23.48	592	382	20	74	633	87	639	9e-16	91.7
rs:WP_013079883	DNA topoisomerase I [Caulobacter segnis].	21.73	681	426	23	1	629	1	626	9e-16	91.7
rs:WP_002883915	DNA topoisomerase I [Streptococcus salivarius].	22.85	582	372	22	83	630	88	626	9e-16	91.7
rs:WP_000024260	topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	9e-16	91.7
rs:WP_043801410	DNA topoisomerase I [Arenimonas malthae].	22.69	573	355	19	3	538	5	526	9e-16	91.7
rs:WP_039669897	DNA topoisomerase I [Coxiella endosymbiont of Amblyomma americanum].	25.84	592	351	28	89	630	67	620	1e-15	91.7
rs:WP_006008809	DNA topoisomerase I [Desulfovibrio piger].	23.05	590	379	18	76	630	53	602	1e-15	91.7
rs:WP_002891063	DNA topoisomerase I [Streptococcus salivarius].	23.09	563	354	22	103	630	108	626	1e-15	91.7
tr:A0A094ZNQ5_SCHHA	SubName: Full=DNA topoisomerase 3-beta-1 {ECO:0000313|EMBL:KGB36300.1};	23.90	498	325	17	95	566	75	544	1e-15	91.7
rs:WP_009057117	DNA topoisomerase I [Nitritalea halalkaliphila].	26.13	532	322	17	3	520	5	479	1e-15	91.7
rs:WP_029070660	DNA topoisomerase I [Kandleria vitulina].	23.15	661	407	24	3	629	4	597	1e-15	91.7
rs:WP_002354010	hypothetical protein, partial [Enterococcus faecium].	28.90	218	139	6	465	667	1	217	1e-15	88.2
rs:WP_035028195	DNA topoisomerase I [Carnobacterium mobile].	23.38	556	369	19	103	630	81	607	1e-15	91.3
rs:WP_002749183	DNA topoisomerase I [Microcystis aeruginosa].	25.04	611	352	23	3	560	4	561	1e-15	91.7
rs:WP_031972313	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	1e-15	91.7
rs:WP_027518393	DNA topoisomerase I [Bradyrhizobium sp. WSM1417].	22.95	706	428	25	1	647	1	649	1e-15	91.7
tr:I0G6C5_9BRAD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.89	686	419	23	1	630	26	657	1e-15	91.7
rs:WP_026526616	DNA topoisomerase I [Butyrivibrio sp. VCD2006].	22.94	558	365	19	90	616	70	593	1e-15	91.3
rs:XP_010943344	PREDICTED: uncharacterized protein LOC105061088 [Elaeis guineensis].	23.06	607	376	25	64	610	349	924	1e-15	92.0
rs:WP_000024267	DNA topoisomerase I subunit omega [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	1e-15	91.7
rs:WP_033917814	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	1e-15	91.7
rs:WP_041748256	DNA topoisomerase I [Bradyrhizobium sp. S23321].	22.89	686	419	23	1	630	1	632	1e-15	91.7
rs:WP_038442188	DNA topoisomerase I [Pseudomonas fluorescens].	23.37	475	306	14	186	633	196	639	1e-15	91.7
rs:WP_000024262	DNA topoisomerase I subunit omega [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	1e-15	91.7
rs:WP_031973291	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	1e-15	91.7
rs:WP_022672346	DNA topoisomerase I [Sphingopyxis baekryungensis].	21.84	664	434	21	1	629	1	614	1e-15	91.7
rs:WP_006619329	DNA topoisomerase I subunit omega [Arthrospira platensis].	23.18	578	341	20	3	530	4	528	1e-15	91.7
rs:WP_023940314	DNA topoisomerase I [Porphyromonas cansulci].	23.97	534	334	16	3	520	5	482	1e-15	91.7
rs:WP_022295489	DNA topoisomerase [Firmicutes bacterium CAG:272].	24.57	582	360	17	90	629	66	610	1e-15	91.7
rs:WP_037117487	DNA topoisomerase I [Rhizobium sp. OV201].	22.49	658	408	25	38	630	16	636	1e-15	91.7
rs:WP_035152627	DNA topoisomerase I [Lactobacillus reuteri].	24.78	577	355	25	90	629	86	620	1e-15	91.3
tr:I9QEE9_HELPX	SubName: Full=Topoisomerase I {ECO:0000313|EMBL:EJB32951.1};	24.69	486	328	14	75	536	46	517	1e-15	91.7
rs:WP_045475869	DNA topoisomerase I [Thioploca ingrica].	24.07	486	306	15	85	534	62	520	1e-15	91.7
rs:WP_015231277	DNA topoisomerase I [Deinococcus peraridilitoris].	25.00	584	350	21	85	631	72	604	1e-15	91.3
rs:WP_022490064	DNA topoisomerase [Clostridium sp. CAG:567].	41.67	120	59	4	3	117	5	118	1e-15	85.5
rs:WP_040919489	DNA topoisomerase I, partial [Leptonema illini].	23.09	680	411	25	3	643	31	637	1e-15	91.3
tr:B6G8D3_9ACTN	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	22.08	566	375	21	77	616	138	663	1e-15	91.7
tr:W1W5N7_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.43	572	360	19	95	629	145	675	1e-15	91.7
rs:WP_039844588	DNA topoisomerase I [Rhizobium gallicum].	22.63	707	399	30	1	630	1	636	1e-15	91.7
rs:WP_019119105	DNA topoisomerase I [Brevibacillus massiliensis].	23.24	555	367	19	105	630	82	606	1e-15	91.3
rs:WP_033861626	DNA topoisomerase III, partial [Staphylococcus aureus].	36.48	159	78	4	467	615	5	150	1e-15	88.2
rs:WP_027044695	DNA topoisomerase I [Mesorhizobium sp. URHC0008].	22.82	701	402	26	1	630	1	633	1e-15	91.7
rs:WP_015769353	DNA topoisomerase I [Leptotrichia buccalis].	24.16	596	355	22	2	566	4	533	1e-15	91.7
rs:WP_015095955	DNA topoisomerase I [Pseudomonas sp. UW4].	23.48	477	303	15	186	633	196	639	1e-15	91.7
rs:WP_004748376	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	1e-15	91.7
rs:WP_035428782	DNA topoisomerase I [Lactobacillus fermentum].	24.35	579	362	26	88	629	85	624	1e-15	91.3
rs:WP_043128999	DNA topoisomerase I [Aeromonas media].	23.60	606	366	22	75	633	82	637	1e-15	91.7
rs:WP_024535012	DNA topoisomerase I [Sporosarcina sp. EUR3 2.2.2].	24.91	562	347	22	105	629	82	605	1e-15	91.3
rs:WP_033659008	DNA topoisomerase, partial [Enterococcus faecium].	28.70	216	138	6	467	667	1	215	1e-15	87.8
rs:WP_026438723	DNA topoisomerase I [Acidocella facilis].	25.19	516	325	17	55	534	28	518	1e-15	91.7
rs:WP_041415332	DNA topoisomerase I [Sinorhizobium fredii].	22.80	693	415	28	1	630	1	636	1e-15	91.7
rs:WP_029910794	DNA topoisomerase I [Hydrogenovibrio marinus].	22.92	528	343	13	3	520	4	477	1e-15	91.7
rs:WP_000655390	DNA topoisomerase I [Helicobacter pylori].	24.85	487	326	15	75	536	46	517	1e-15	91.3
rs:WP_032068885	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	1e-15	91.7
rs:WP_032043705	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	1e-15	91.7
rs:WP_023937657	DNA topoisomerase I [Porphyromonas crevioricanis].	23.97	534	334	16	3	520	5	482	1e-15	91.7
rs:WP_031563836	DNA topoisomerase I [Legionella wadsworthii].	23.57	628	391	25	55	630	29	619	1e-15	91.7
rs:WP_022293461	DNA topoisomerase [Eubacterium rectale CAG:36].	24.20	562	353	20	90	616	67	590	1e-15	91.3
tr:K4E7B0_TRYCR	SubName: Full=DNA topoisomerase III, putative {ECO:0000313|EMBL:EKG06290.1};	22.80	592	395	18	3	564	6	565	1e-15	91.7
rs:WP_027567322	DNA topoisomerase I [Bradyrhizobium sp. URHA0013].	22.95	706	428	25	1	647	1	649	1e-15	91.7
rs:WP_035685277	DNA topoisomerase I [Flavobacterium reichenbachii].	24.72	534	326	20	3	521	5	477	1e-15	91.7
rs:WP_031999729	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	1e-15	91.7
rs:WP_017519284	topoisomerase I [Pseudomonas nitroreducens].	23.48	477	301	14	187	633	195	637	1e-15	91.7
rs:WP_045737421	DNA topoisomerase I [Xanthomonas sp. MUS 060].	24.08	573	347	19	3	538	5	526	1e-15	91.7
rs:WP_044478341	DNA topoisomerase I [Paenibacillus sp. GD11].	23.29	584	383	22	88	636	62	615	1e-15	91.3
rs:WP_016390852	MULTISPECIES: DNA topoisomerase I [Cycloclasticus].	24.27	684	394	28	3	630	4	619	1e-15	91.7
rs:WP_042054514	DNA topoisomerase I [Aeromonas veronii].	23.76	606	365	23	75	633	82	637	1e-15	91.7
rs:XP_007973100	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Chlorocebus sabaeus].	25.30	415	260	14	188	585	76	457	1e-15	91.3
rs:WP_024434017	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	1e-15	91.7
rs:WP_045211687	DNA topoisomerase I [Pseudomonas sp. 21].	23.48	477	301	14	187	633	195	637	1e-15	91.7
rs:WP_003050739	DNA topoisomerase I [Streptococcus dysgalactiae].	22.99	561	356	23	103	629	98	616	1e-15	91.3
rs:WP_032953621	DNA topoisomerase I, partial [Bacteroides vulgatus].	33.33	201	124	5	89	284	2	197	1e-15	87.0
rs:WP_037599980	DNA topoisomerase I [Streptococcus sp. ACS2].	23.13	562	355	22	103	630	108	626	1e-15	91.3
rs:WP_046025708	DNA topoisomerase I [Lactobacillus fermentum].	24.35	579	362	26	88	629	85	624	1e-15	91.3
rs:WP_018261492	DNA topoisomerase [Methylobacterium sp. WSM2598].	22.18	550	346	24	33	520	17	546	1e-15	91.7
rs:WP_001896186	DNA topoisomerase 3, partial [Vibrio cholerae].	32.43	185	112	6	2	179	3	181	1e-15	86.7
tr:A0A0D6N3W7_9PROT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAN60243.1};	22.38	639	401	22	55	630	28	634	1e-15	91.7
rs:WP_023409931	hypothetical protein [uncultured Thiohalocapsa sp. PB-PSB1].	25.75	299	199	9	299	574	9	307	1e-15	90.1
rs:WP_014105207	DNA topoisomerase I [Komagataeibacter medellinensis].	21.63	638	408	25	55	630	28	635	1e-15	91.7
rs:WP_034317776	DNA topoisomerase I [Bacillus sp. DW5-4].	24.32	514	329	21	154	636	130	614	1e-15	91.3
rs:WP_000557252	hypothetical protein, partial [Streptococcus agalactiae].	29.43	333	205	15	3	319	4	322	1e-15	89.0
rs:WP_025643059	DNA topoisomerase I [Clostridiales bacterium VE202-26].	22.00	700	417	24	3	629	5	648	1e-15	91.3
rs:WP_009345264	DNA topoisomerase I [Peptoniphilus sp. oral taxon 836].	22.45	717	440	28	3	678	5	646	1e-15	91.3
rs:WP_042746299	DNA topoisomerase I [Lactobacillus reuteri].	23.96	576	361	22	90	629	86	620	1e-15	91.3
rs:WP_019251607	DNA topoisomerase I [Lactobacillus reuteri].	24.78	577	355	25	90	629	86	620	1e-15	91.3
rs:WP_008037710	topoisomerase I [Pseudomonas sp. GM67].	23.53	476	304	14	186	633	196	639	1e-15	91.7
rs:WP_005568750	topoisomerase I [Aggregatibacter actinomycetemcomitans].	23.27	477	304	13	187	633	196	640	1e-15	91.7
rs:WP_009536215	DNA topoisomerase I [Oribacterium asaccharolyticum].	23.38	663	380	24	3	616	5	588	1e-15	91.3
rs:WP_005353832	topoisomerase I [Aeromonas veronii].	23.76	606	365	23	75	633	82	637	1e-15	91.7
rs:WP_045621564	DNA topoisomerase I [Vibrio vulnificus].	23.79	618	380	21	60	633	69	639	1e-15	91.7
tr:W8GS60_9MOLU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00003390}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.69	567	359	20	88	629	74	597	1e-15	91.3
rs:WP_020800560	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	23.16	475	307	14	186	633	196	639	1e-15	91.7
rs:WP_000024263	DNA topoisomerase I subunit omega [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	1e-15	91.7
rs:WP_000024264	topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	1e-15	91.7
rs:WP_004738038	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	1e-15	91.7
rs:WP_044226506	DNA topoisomerase I [Coprobacter sp. 177].	26.27	472	279	15	77	521	54	483	1e-15	91.3
rs:WP_040360493	DNA topoisomerase [Collinsella stercoris].	22.08	566	375	21	77	616	125	650	1e-15	91.7
rs:WP_034147900	DNA topoisomerase I [Pseudomonas fluorescens].	23.48	477	303	15	186	633	196	639	1e-15	91.7
rs:WP_000024261	topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	1e-15	91.7
rs:WP_038046302	hypothetical protein [Thermoanaerobaculum aquaticum].	22.09	670	419	21	2	631	4	610	1e-15	91.3
rs:XP_011073927	PREDICTED: DNA topoisomerase 3-beta isoform X3 [Sesamum indicum].	22.81	605	396	20	60	631	11	577	1e-15	91.7
rs:WP_028498669	DNA topoisomerase I [Microvirgula aerodenitrificans].	22.41	665	424	22	3	630	5	614	1e-15	91.3
rs:WP_044405059	DNA topoisomerase I [Pseudomonas sp. FeS53a].	23.35	591	384	19	74	633	86	638	1e-15	91.7
rs:WP_022232935	DNA topoisomerase [Bacteroides sp. CAG:443].	23.62	618	392	19	3	604	5	558	1e-15	91.3
tr:A0A0B8P485_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAM61590.1};	36.80	125	79	0	457	581	65	189	1e-15	87.4
rs:WP_022211946	DNA topoisomerase III-like protein, partial [Clostridium sp. CAG:265].	27.83	230	151	6	465	680	71	299	1e-15	88.6
rs:WP_004710690	DNA topoisomerase I [Acinetobacter nosocomialis].	23.53	595	368	19	74	629	100	646	1e-15	91.7
rs:WP_022281084	DNA topoisomerase [Clostridium sp. CAG:448].	23.36	672	411	26	3	630	4	615	1e-15	91.3
rs:WP_042648448	DNA topoisomerase I [Aeromonas media].	22.95	597	381	19	75	633	82	637	1e-15	91.7
tr:W7TAY5_9STRA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.70	555	358	20	36	560	47	560	1e-15	91.7
tr:A0A075GQE8_9EURY	SubName: Full=DNA topoisomerase I (TopA) {ECO:0000313|EMBL:AIF05984.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AIF05984.1};	24.55	554	325	22	98	608	84	587	1e-15	91.3
gpu:CP011144_1268	DNA topoisomerase I [Pseudoxanthomonas suwonensis]	25.59	469	294	15	103	538	80	526	1e-15	91.7
rs:WP_008379664	DNA topoisomerase I [Enterococcus sp. C1].	25.17	572	351	24	103	635	81	614	1e-15	91.3
rs:WP_043777938	hypothetical protein, partial [Deinococcus ficus].	25.83	511	305	17	64	533	51	528	1e-15	90.9
rs:WP_043272436	hypothetical protein [Pseudomonas sp. AAC].	27.53	178	122	3	1	177	1	172	1e-15	86.7
rs:WP_039210129	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	1e-15	91.7
rs:WP_017698104	DNA topoisomerase I [Mycoplasma mycoides].	24.15	675	387	30	3	625	4	605	1e-15	91.3
rs:WP_010483129	topoisomerase I [Pseudomonas sp. S9].	25.31	482	288	18	186	633	195	638	1e-15	91.7
rs:WP_017496994	DNA topoisomerase I [Flavobacterium sp. WG21].	25.14	533	325	20	3	521	5	477	1e-15	91.7
rs:WP_045596646	DNA topoisomerase I [Vibrio vulnificus].	23.79	618	380	21	60	633	69	639	1e-15	91.7
tr:A0A0C7SBB9_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.60	569	345	20	103	631	81	605	1e-15	91.3
rs:WP_018932685	DNA topoisomerase I [Gracilibacillus lacisalsi].	23.93	585	369	21	90	635	67	614	1e-15	91.3
tr:F8LFA1_9CHLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.10	610	355	23	82	630	59	621	1e-15	91.7
tr:I3X7P4_RHIFR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.80	693	415	28	1	630	3	638	1e-15	91.7
rs:WP_039972512	DNA topoisomerase I [Bacteroides pyogenes].	23.88	469	303	13	77	526	54	487	1e-15	91.3
rs:WP_006036001	DNA topoisomerase I [Rickettsiella grylli].	23.59	674	412	28	76	687	53	685	1e-15	91.3
rs:WP_025547373	DNA topoisomerase I [Sphingobium sp. KK22].	21.40	673	426	21	1	629	1	614	1e-15	91.3
rs:WP_022013312	DNA topoisomerase [Clostridium sp. CAG:122].	24.56	562	349	21	90	616	67	588	1e-15	91.3
rs:WP_006906309	DNA topoisomerase I [Shuttleworthia satelles].	22.36	644	411	19	3	616	5	589	1e-15	91.3
rs:WP_042467105	DNA topoisomerase I [Aeromonas salmonicida].	23.60	606	366	22	75	633	82	637	1e-15	91.7
rs:WP_028977943	DNA topoisomerase I [Sporolactobacillus terrae].	24.34	567	363	22	105	635	82	618	1e-15	91.3
rs:WP_017346259	topoisomerase I [Pantoea sp. A4].	23.10	645	400	23	75	673	79	673	1e-15	91.3
tr:K2CW40_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.26	675	404	25	3	629	4	612	1e-15	90.9
rs:WP_027425646	DNA topoisomerase I [Lachnospiraceae bacterium NC2004].	23.96	626	401	20	83	675	54	637	1e-15	91.3
tr:L2Q590_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELB49113.1};	29.58	213	134	6	470	667	5	216	1e-15	87.8
rs:WP_005921909	DNA topoisomerase I [Xanthomonas axonopodis].	23.56	573	338	23	3	538	5	514	1e-15	91.3
rs:WP_042434696	DNA topoisomerase [Senegalimassilia anaerobia].	23.67	562	352	19	90	614	135	656	1e-15	91.3
rs:WP_021019037	topoisomerase I [Vibrio gazogenes].	22.75	633	357	20	57	633	84	640	1e-15	91.3
rs:WP_045544581	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	1e-15	91.3
rs:WP_010703721	DNA topoisomerase I [Bartonella schoenbuchensis].	23.30	691	410	31	1	629	1	633	1e-15	91.3
rs:WP_034325702	DNA topoisomerase I [Helicobacter sp. MIT 03-1616].	23.55	603	368	19	55	614	28	580	1e-15	91.3
rs:WP_003092737	DNA topoisomerase I [Streptococcus vestibularis].	23.13	562	355	22	103	630	104	622	1e-15	91.3
rs:WP_035147206	DNA topoisomerase III, partial [Lactobacillus sakei].	27.59	261	157	5	351	610	1	230	1e-15	88.6
rs:WP_045728597	DNA topoisomerase I [Xanthomonas sp. GPE 39].	24.08	573	347	19	3	538	5	526	1e-15	91.3
tr:H2CDW9_9LEPT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.09	680	411	25	3	643	52	658	1e-15	91.3
rs:WP_046306847	DNA topoisomerase I [Lactobacillus apis].	24.73	562	348	22	103	629	89	610	1e-15	91.3
rs:WP_022147116	DNA topoisomerase [Bacteroides sp. CAG:709].	28.70	331	204	9	76	392	59	371	1e-15	91.3
tr:C4UJJ0_YERRU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.19	608	366	19	74	633	61	615	1e-15	91.3
rs:WP_002053435	MULTISPECIES: topoisomerase I [Acinetobacter calcoaceticus/baumannii complex].	23.53	595	368	19	74	629	100	646	1e-15	91.3
rs:WP_046826724	DNA topoisomerase I [Afipia sp. LC387].	24.02	687	409	29	1	629	1	632	1e-15	91.3
rs:XP_003662864	hypothetical protein MYCTH_2303986 [Myceliophthora thermophila ATCC 42464].	23.59	568	337	24	3	521	5	524	1e-15	90.9
rs:WP_008436951	DNA topoisomerase I [Rhodanobacter thiooxydans].	22.71	612	391	16	77	638	54	633	1e-15	91.3
rs:WP_037426547	DNA topoisomerase I, partial [Shewanella sp. POL2].	23.24	482	295	16	187	631	50	493	1e-15	91.3
rs:WP_045595170	DNA topoisomerase I [Vibrio vulnificus].	23.91	619	378	23	60	633	69	639	1e-15	91.3
rs:WP_034130508	DNA topoisomerase I [Peptococcaceae bacterium BICA1-8].	22.15	650	404	21	3	616	5	588	1e-15	91.3
rs:WP_038020773	DNA topoisomerase I [Tatumella morbirosei].	22.95	475	308	13	187	633	190	634	1e-15	91.3
rs:WP_044203945	DNA topoisomerase I [Flammeovirga sp. OC4].	25.51	541	315	19	3	520	5	480	1e-15	91.3
rs:WP_003668086	DNA topoisomerase I [Lactobacillus reuteri].	24.78	577	355	25	90	629	86	620	1e-15	91.3
rs:WP_036853384	DNA topoisomerase I [Prevotella denticola].	23.11	610	363	21	3	580	5	540	1e-15	91.3
tr:U2CMC3_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.88	469	303	13	77	526	69	502	1e-15	91.3
rs:WP_039953520	DNA topoisomerase I [Bacteroides eggerthii].	24.84	624	367	24	3	596	5	556	1e-15	91.3
tr:B7AKT4_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.84	624	367	24	3	596	15	566	1e-15	91.3
rs:WP_040047345	DNA topoisomerase I [Bacillaceae bacterium MTCC 8252].	23.34	557	367	18	105	629	82	610	1e-15	90.9
tr:C6SEJ0_NEIME	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.97	727	451	27	3	679	58	725	1e-15	91.3
rs:WP_026294208	DNA topoisomerase I [Saccharibacter floricola].	21.71	645	398	24	55	631	28	633	1e-15	91.3
rs:WP_019210093	topoisomerase I [Yersinia massiliensis].	24.02	612	356	22	74	633	87	641	1e-15	91.3
rs:WP_030425043	DNA topoisomerase I, partial [Acinetobacter baumannii].	23.66	596	366	20	75	629	86	633	1e-15	91.3
rs:WP_030139950	DNA topoisomerase I [Pseudomonas fluorescens].	23.69	477	302	15	186	633	196	639	1e-15	91.3
rs:WP_027629548	DNA topoisomerase I [[Clostridium] cellobioparum].	22.31	614	387	20	103	671	80	648	1e-15	90.9
rs:WP_018141432	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	23.02	569	348	21	3	534	5	520	1e-15	91.3
rs:WP_016186990	DNA topoisomerase III, partial [Staphylococcus aureus].	36.48	159	78	4	467	615	43	188	1e-15	88.2
rs:WP_035487194	hypothetical protein, partial [Geminicoccus roseus].	21.74	690	424	25	1	630	1	634	1e-15	91.3
tr:W4V4V0_9FIRM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE88435.1};	33.33	141	90	3	31	168	12	151	1e-15	85.9
rs:WP_009562909	DNA topoisomerase I [Rhodobacter sp. AKP1].	22.53	657	405	25	1	611	1	599	1e-15	91.3
rs:WP_026666020	DNA topoisomerase I [Butyrivibrio sp. FC2001].	23.74	556	363	18	90	616	70	593	1e-15	90.9
rs:WP_033855510	DNA topoisomerase I [Acinetobacter baumannii].	23.53	595	368	19	74	629	100	646	1e-15	91.3
rs:WP_031952294	DNA topoisomerase I [Acinetobacter baumannii].	23.53	595	368	19	74	629	100	646	1e-15	91.3
rs:WP_016613225	DNA topoisomerase I [Enterococcus faecium].	25.17	572	351	24	103	635	81	614	1e-15	90.9
rs:WP_046402617	DNA topoisomerase I [Odoribacter sp. N15.MGS-14].	24.16	538	323	18	3	520	5	477	1e-15	91.3
rs:WP_043041331	DNA topoisomerase I [Acinetobacter baumannii].	23.66	579	355	19	90	629	116	646	1e-15	91.3
rs:WP_032044815	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	1e-15	91.3
rs:WP_003506900	DNA topoisomerase I [[Clostridium] symbiosum].	23.99	621	388	23	90	671	67	642	1e-15	90.9
rs:WP_026348843	DNA topoisomerase I [Psychrobacter lutiphocae].	23.97	655	384	26	77	673	100	698	1e-15	91.3
rs:WP_031974178	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	1e-15	91.3
rs:WP_001681279	DNA topoisomerase III, partial [Salmonella enterica].	36.59	123	78	0	459	581	1	123	1e-15	86.3
rs:WP_000655389	DNA topoisomerase I [Helicobacter pylori].	24.59	484	331	14	75	536	46	517	1e-15	90.9
rs:WP_004876200	topoisomerase I [Yersinia mollaretii].	24.02	612	356	22	74	633	87	641	1e-15	91.3
rs:WP_037399481	DNA topoisomerase I [Sinorhizobium fredii].	22.37	693	418	27	1	630	1	636	1e-15	91.3
rs:WP_039344991	DNA topoisomerase I [Pectobacterium carotovorum].	23.76	644	397	24	74	673	80	673	1e-15	91.3
rs:WP_040092879	DNA topoisomerase I [Spiroplasma poulsonii].	24.40	668	410	24	3	643	5	604	1e-15	90.9
rs:WP_012509456	DNA topoisomerase I [Pelodictyon phaeoclathratiforme].	23.90	615	384	17	76	642	63	641	1e-15	91.3
rs:WP_011959681	topoisomerase I [Psychrobacter sp. PRwf-1].	24.04	653	385	24	77	673	97	694	1e-15	91.3
rs:WP_034343711	DNA topoisomerase I [Helicobacter typhlonius].	23.55	603	368	19	55	614	28	580	1e-15	90.9
rs:WP_037555750	DNA topoisomerase I [Sphingopyxis sp. LC363].	22.41	665	430	23	1	629	1	615	1e-15	91.3
rs:WP_018589680	DNA topoisomerase I [Terrisporobacter glycolicus].	25.00	604	372	23	103	671	81	638	1e-15	90.9
rs:WP_018572256	DNA topoisomerase I [Prevotella micans].	25.50	400	249	9	3	392	5	365	1e-15	91.3
rs:XP_011738035	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Macaca nemestrina].	24.52	416	262	13	188	585	151	532	1e-15	91.3
rs:WP_021576142	DNA topoisomerase 1 [Escherichia coli].	23.46	601	380	24	73	633	74	634	1e-15	91.3
rs:WP_040572300	DNA topoisomerase I [Selenomonas flueggei].	23.07	672	416	25	3	636	33	641	1e-15	91.3
rs:WP_028900957	DNA topoisomerase I [Prevotella timonensis].	23.14	592	375	18	3	578	5	532	1e-15	91.3
rs:WP_038242556	DNA topoisomerase I [Yersinia ruckeri].	23.19	608	366	19	74	633	86	640	1e-15	91.3
rs:WP_034455256	DNA topoisomerase I [Bartonella quintana].	22.64	698	406	27	1	629	1	633	1e-15	91.3
rs:WP_019692747	topoisomerase I [Pseudomonas fluorescens].	23.74	476	301	15	187	633	197	639	1e-15	91.3
rs:WP_033902579	DNA topoisomerase I [Pseudomonas sp. FH1].	23.47	473	306	13	187	633	197	639	1e-15	91.3
rs:WP_007611239	DNA topoisomerase I [Bradyrhizobium sp. WSM471].	22.95	706	428	25	1	647	1	649	1e-15	91.3
rs:WP_042729272	DNA topoisomerase I [Pseudomonas fluorescens].	22.97	592	385	20	74	633	87	639	1e-15	91.3
rs:WP_033790335	DNA topoisomerase I [Pantoea sp. FF5].	23.83	600	372	21	74	633	80	634	1e-15	91.3
rs:WP_045967592	DNA topoisomerase I [Flavobacterium sp. 316].	24.29	531	332	19	3	521	5	477	1e-15	91.3
rs:WP_034815084	DNA topoisomerase I [Exiguobacterium alkaliphilum].	22.74	664	417	27	3	629	5	609	1e-15	90.9
rs:WP_011759437	topoisomerase I [Shewanella amazonensis].	22.32	596	387	18	75	633	87	643	1e-15	91.3
rs:WP_024351714	DNA topoisomerase I [Aurantimonas coralicida].	22.82	710	420	31	1	643	1	649	1e-15	91.3
rs:XP_004233765	PREDICTED: uncharacterized protein LOC101248941 isoform X2 [Solanum lycopersicum].	27.13	516	308	24	64	536	408	898	1e-15	91.3
rs:WP_039334683	DNA topoisomerase I [Pantoea rodasii].	23.35	484	295	17	187	633	190	634	1e-15	91.3
rs:XP_005567917	PREDICTED: DNA topoisomerase 3-beta-1 isoform X5 [Macaca fascicularis].	24.52	416	262	13	188	585	76	457	1e-15	90.9
rs:WP_023466136	DNA topoisomerase I [Lactobacillus fermentum].	24.35	579	362	26	88	629	85	624	1e-15	90.9
rs:WP_003674222	DNA topoisomerase I [Lactobacillus reuteri].	24.78	577	355	25	90	629	86	620	1e-15	90.9
rs:WP_007994702	topoisomerase I [Pseudomonas sp. GM49].	23.48	477	303	15	186	633	196	639	1e-15	91.3
rs:XP_006692995	DNA topoisomerase-like protein [Chaetomium thermophilum var. thermophilum DSM 1495].	23.78	576	338	22	3	526	5	531	1e-15	90.9
rs:WP_004715579	topoisomerase I [Yersinia rohdei].	23.28	653	389	23	74	673	86	679	1e-15	91.3
rs:WP_034211709	DNA topoisomerase I [Arenimonas metalli].	23.40	470	299	13	103	536	80	524	1e-15	91.3
tr:E5X107_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.68	624	368	24	3	596	15	566	1e-15	91.3
rs:WP_038846550	DNA topoisomerase I [Pseudomonas fluorescens].	23.42	474	307	13	186	633	196	639	1e-15	91.3
rs:WP_009555384	DNA topoisomerase I [Oscillatoriales cyanobacterium JSC-12].	23.05	629	379	21	3	577	4	581	1e-15	91.3
rs:WP_020210913	hypothetical protein [Gilvimarinus chinensis].	22.47	721	451	28	1	684	1	650	1e-15	90.9
rs:WP_046863367	DNA topoisomerase I [Microvirga sp. JC119].	23.55	692	405	34	1	629	1	631	1e-15	91.3
rs:WP_008023008	topoisomerase I [Pseudomonas sp. GM55].	23.48	477	303	15	186	633	196	639	1e-15	91.3
rs:WP_019827482	DNA topoisomerase I [Pseudomonas sp. CF149].	22.99	596	380	20	74	633	87	639	1e-15	91.3
rs:XP_004323500	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-beta-1-like [Tursiops truncatus].	23.67	566	364	20	3	537	5	533	1e-15	90.9
rs:WP_040211709	DNA topoisomerase I [Clostridium sp. MS1].	23.35	621	354	21	90	630	67	645	1e-15	90.9
rs:WP_035427363	DNA topoisomerase I [Lactobacillus fermentum].	24.35	579	362	26	88	629	83	622	1e-15	90.9
rs:WP_032048135	DNA topoisomerase I [Acinetobacter baumannii].	23.53	595	368	19	74	629	100	646	1e-15	91.3
rs:XP_011632249	PREDICTED: DNA topoisomerase 3-beta-1, partial [Pogonomyrmex barbatus].	22.32	578	368	19	3	537	5	544	1e-15	90.5
rs:WP_027201850	DNA topoisomerase I [Butyricimonas virosa].	24.49	543	319	19	3	520	5	481	1e-15	90.9
rs:WP_035574515	DNA topoisomerase I, partial [Elioraea tepidiphila].	21.42	691	423	26	1	630	1	632	2e-15	91.3
tr:A0A0D6SKK9_9RHIZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KIV69166.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIV69166.1};	23.27	636	372	27	70	630	1	595	2e-15	91.3
rs:WP_045008032	DNA topoisomerase I [Bradyrhizobium sp. LTSP857].	23.08	689	414	25	1	630	1	632	2e-15	91.3
rs:WP_012333944	DNA topoisomerase [Methylobacterium sp. 4-46].	21.82	550	348	23	33	520	17	546	2e-15	90.9
rs:WP_008466614	topoisomerase I [Pseudoalteromonas sp. BSi20439].	23.05	616	384	22	60	631	72	641	2e-15	91.3
rs:WP_002350893	hypothetical protein, partial [Enterococcus faecium].	28.70	216	138	6	467	667	1	215	2e-15	87.4
rs:WP_009524712	DNA topoisomerase I [Peptostreptococcaceae bacterium ACC19a].	25.26	681	383	33	3	635	4	606	2e-15	90.9
rs:WP_035486060	DNA topoisomerase I, partial [Alicyclobacillus contaminans].	23.42	568	353	20	88	614	62	588	2e-15	90.9
rs:WP_013555570	DNA topoisomerase I [Deinococcus maricopensis].	23.65	575	341	20	3	533	4	524	2e-15	90.9
rs:WP_031877302	DNA topoisomerase III, partial [Staphylococcus aureus].	36.48	159	78	4	467	615	31	176	2e-15	87.8
rs:WP_017927245	DNA topoisomerase I [Loktanella hongkongensis].	22.29	655	371	24	1	587	1	585	2e-15	91.3
rs:WP_036543456	DNA topoisomerase I [Nocardioides sp. UNC345MFTsu5.1].	24.91	582	332	25	2	528	4	535	2e-15	91.3
rs:WP_034548728	DNA topoisomerase I [Carnobacterium alterfunditum].	23.54	582	374	22	90	635	68	614	2e-15	90.9
rs:WP_008424783	DNA topoisomerase I [Clostridium sp. Maddingley MBC34-26].	24.50	653	389	24	2	618	4	588	2e-15	90.9
rs:WP_027243366	DNA topoisomerase I [Leisingera daeponensis].	23.99	646	392	26	55	630	27	643	2e-15	91.3
rs:WP_038953673	DNA topoisomerase I [Bradyrhizobium japonicum].	22.89	686	419	23	1	630	1	632	2e-15	91.3
tr:T0TU76_LACFE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.35	579	362	26	88	629	85	624	2e-15	90.9
rs:WP_017411764	topoisomerase I [Aeromonas salmonicida].	23.60	606	366	22	75	633	82	637	2e-15	90.9
rs:WP_027617977	DNA topoisomerase I [Pseudomonas sp. URHB0015].	23.95	476	300	15	187	633	197	639	2e-15	90.9
rs:WP_005398276	DNA topoisomerase I [Helcococcus kunzii].	23.46	648	392	25	3	615	5	583	2e-15	90.9
rs:WP_025315708	DNA topoisomerase I [Gilliamella apicola].	23.67	600	374	18	74	633	79	634	2e-15	90.9
rs:WP_035670243	DNA topoisomerase I [Flavobacterium sp. 83].	24.49	535	326	19	3	521	5	477	2e-15	90.9
rs:WP_019132545	hypothetical protein [Peptoniphilus obesi].	24.28	556	356	19	90	616	67	586	2e-15	90.9
rs:WP_009425403	DNA topoisomerase I [Neisseria sp. oral taxon 020].	22.77	729	450	27	3	679	5	672	2e-15	90.9
rs:WP_024853033	DNA topoisomerase I [[Ruminococcus] gnavus].	23.61	559	359	17	90	616	67	589	2e-15	90.9
tr:K2A4J6_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.78	677	423	21	1	644	3	619	2e-15	90.5
rs:WP_003475272	DNA topoisomerase I [Clostridium perfringens].	23.12	705	403	26	2	630	4	645	2e-15	90.9
rs:WP_035169862	DNA topoisomerase I [Lactobacillus reuteri].	24.78	577	355	25	90	629	86	620	2e-15	90.9
rs:WP_013612667	DNA topoisomerase I [Odoribacter splanchnicus].	24.16	538	323	18	3	520	5	477	2e-15	90.9
rs:WP_006492023	DNA topoisomerase 1 [Mesotoga infera].	23.40	594	372	17	2	571	4	538	2e-15	90.9
rs:WP_034716810	DNA topoisomerase I [Bacteroides eggerthii].	24.68	624	368	24	3	596	5	556	2e-15	90.9
tr:A0A059EXB5_9MICR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KCZ79502.1};	24.08	598	390	18	1	573	1	559	2e-15	90.9
rs:WP_041257161	DNA topoisomerase I, partial [Fervidobacterium nodosum].	24.21	661	395	25	2	631	8	593	2e-15	90.5
tr:A0A0D6AKL8_9CHRO	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:BAQ63366.1};	24.72	627	362	25	3	574	4	575	2e-15	90.9
rs:WP_043363592	DNA topoisomerase I [Belnapia sp. F-4-1].	23.29	627	375	23	55	610	28	619	2e-15	91.3
rs:WP_010470849	DNA topoisomerase I [Acaryochloris sp. CCMEE 5410].	24.56	574	353	20	81	614	61	594	2e-15	90.9
rs:WP_021845568	DNA topoisomerase [Blautia hydrogenotrophica CAG:147].	24.11	564	349	22	90	616	67	588	2e-15	90.9
rs:WP_026283306	DNA topoisomerase I [Rhizobium sp. 2MFCol3.1].	22.80	706	399	30	1	630	1	636	2e-15	90.9
rs:WP_003083749	DNA topoisomerase I [Streptococcus porcinus].	22.01	577	382	20	83	629	83	621	2e-15	90.9
rs:WP_008256456	DNA topoisomerase I [Flavobacteria bacterium BAL38].	24.70	660	403	29	3	623	5	609	2e-15	90.9
tr:D2I7M2_AILME	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.28	416	263	13	188	585	189	570	2e-15	90.9
rs:XP_004502266	PREDICTED: DNA topoisomerase 3-beta isoform X3 [Cicer arietinum].	22.83	530	354	14	126	631	30	528	2e-15	90.9
rs:WP_022037788	DNA topoisomerase [Ruminococcus gnavus CAG:126].	23.61	559	359	17	90	616	67	589	2e-15	90.9
rs:WP_035966600	DNA topoisomerase I [Bradyrhizobium sp. YR681].	23.03	686	418	23	1	630	1	632	2e-15	90.9
tr:A0A034TX81_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.68	153	96	3	244	390	17	168	2e-15	87.4
tr:H1Q1U3_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.50	400	249	9	3	392	24	384	2e-15	90.9
rs:WP_008391297	DNA topoisomerase I [Clostridium sp. SS2/1].	23.78	576	350	18	83	616	60	588	2e-15	90.9
rs:WP_010673895	MULTISPECIES: topoisomerase I [Aeromonas].	24.13	489	285	18	187	633	193	637	2e-15	90.9
rs:WP_045012346	DNA topoisomerase I [Bradyrhizobium sp. LTSP849].	23.08	689	414	25	1	630	1	632	2e-15	90.9
rs:XP_001566225	putative DNA topoisomerase III [Leishmania braziliensis MHOM/BR/75/M2904].	22.08	607	396	19	3	571	6	573	2e-15	90.9
rs:WP_046403146	DNA topoisomerase I [Odoribacter sp. UNK.MGS-12].	24.16	538	323	18	3	520	5	477	2e-15	90.9
rs:WP_041208968	DNA topoisomerase I [Aeromonas jandaei].	24.09	606	363	23	75	633	82	637	2e-15	90.9
rs:WP_013597664	DNA topoisomerase I [Weeksella virosa].	24.58	533	329	16	3	521	5	478	2e-15	90.9
rs:XP_004223545	DNA topoisomerase III alpha [Plasmodium cynomolgi strain B].	24.15	646	337	24	3	555	7	592	2e-15	90.5
rs:WP_026398617	DNA topoisomerase I [Acetobacter nitrogenifigens].	21.62	606	383	23	85	630	61	634	2e-15	90.9
tr:X0TLT1_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_S01025 {ECO:0000313|EMBL:GAF94503.1}; Flags: Fragment;	30.00	250	157	8	159	396	28	271	2e-15	87.8
rs:WP_002558218	MULTISPECIES: DNA topoisomerase I [Bacteroides].	25.00	564	346	21	74	613	51	561	2e-15	90.9
rs:WP_005278299	topoisomerase I [Yersinia bercovieri].	23.81	609	361	21	74	633	87	641	2e-15	90.9
tr:I0GNA0_SELRL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.95	553	359	19	90	616	82	604	2e-15	90.9
rs:WP_010555034	topoisomerase I [Pseudoalteromonas arctica].	23.44	593	375	20	76	631	91	641	2e-15	90.9
rs:WP_036893779	DNA topoisomerase I [Prevotella sp. S7-1-8].	23.37	646	417	21	3	618	5	602	2e-15	90.9
rs:WP_012023927	DNA topoisomerase I [Flavobacterium johnsoniae].	25.42	535	321	20	3	521	5	477	2e-15	90.9
rs:WP_014127330	DNA topoisomerase [Thermoproteus tenax].	22.29	628	411	21	3	596	2	586	2e-15	90.5
rs:WP_011840645	DNA topoisomerase I [Rhodobacter sphaeroides].	23.00	661	397	26	1	611	1	599	2e-15	90.9
rs:WP_044275446	DNA topoisomerase I [Pseudomonas fluorescens].	22.83	565	374	14	77	614	62	591	2e-15	90.5
rs:WP_012391203	DNA topoisomerase I [Lactobacillus fermentum].	23.53	578	368	23	88	629	85	624	2e-15	90.5
rs:WP_007669468	DNA topoisomerase I [alpha proteobacterium BAL199].	24.51	714	399	37	2	645	3	646	2e-15	90.9
rs:WP_028621958	DNA topoisomerase I [Pseudomonas sp. Ant30-3].	23.16	475	307	14	186	633	196	639	2e-15	90.9
rs:WP_045089368	DNA topoisomerase I [Porphyromonadaceae bacterium ING2-E5B].	23.40	547	325	18	3	523	5	483	2e-15	90.9
rs:WP_020029559	hypothetical protein [gamma proteobacterium SCGC AAA076-P13].	23.00	587	377	21	60	616	67	608	2e-15	90.9
tr:M2TPP4_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.53	680	406	26	3	629	11	629	2e-15	90.9
rs:WP_007477343	DNA topoisomerase I [Bartonella melophagi].	23.15	691	411	30	1	629	1	633	2e-15	90.9
rs:WP_023526812	DNA topoisomerase I [Helicobacter pylori].	24.24	491	324	13	75	536	46	517	2e-15	90.5
rs:WP_005312182	topoisomerase I [Aeromonas salmonicida].	23.60	606	366	22	75	633	82	637	2e-15	90.9
rs:WP_029314681	DNA topoisomerase I [Acidiphilium angustum].	22.56	634	403	23	55	630	28	631	2e-15	90.9
tr:J3CRJ2_9BRAD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952}; Flags: Precursor;	23.03	686	418	23	1	630	26	657	2e-15	90.9
rs:WP_008990855	DNA topoisomerase I [Galbibacter marinus].	25.00	532	327	18	3	521	5	477	2e-15	90.9
rs:WP_040940167	hypothetical protein, partial [Prochloron didemni].	22.01	627	384	21	3	572	4	582	2e-15	90.9
tr:Q31J81_THICR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.13	536	332	17	3	520	4	477	2e-15	90.9
rs:WP_008028483	topoisomerase I [Pseudomonas sp. GM60].	23.32	476	305	14	186	633	196	639	2e-15	90.9
rs:WP_011747004	DNA topoisomerase I [Paracoccus denitrificans].	22.83	692	401	29	1	630	1	621	2e-15	90.9
rs:WP_004842577	DNA topoisomerase I [Acinetobacter baumannii].	23.66	579	355	19	90	629	116	646	2e-15	90.9
tr:A0A0A4HI73_9PSED	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.69	477	302	15	186	633	196	639	2e-15	90.9
rs:WP_027138598	DNA topoisomerase I [Gaetbulibacter saemankumensis].	23.44	529	339	16	3	521	5	477	2e-15	90.9
rs:WP_007986365	topoisomerase I [Pseudomonas sp. GM48].	23.48	477	303	15	186	633	196	639	2e-15	90.9
rs:WP_007487544	DNA topoisomerase I [Bacteroides nordii].	25.00	564	346	21	74	613	51	561	2e-15	90.9
rs:WP_003001121	DNA topoisomerase I [Sphingobacterium spiritivorum].	24.79	476	294	15	76	526	53	489	2e-15	90.9
rs:XP_006894616	PREDICTED: DNA topoisomerase 3-beta-1-like [Elephantulus edwardii].	21.71	631	404	22	3	585	5	593	2e-15	90.9
rs:WP_038281608	DNA topoisomerase I [alpha proteobacterium JLT2015].	23.53	680	406	26	3	629	5	623	2e-15	90.9
tr:S5Z6S0_9CREN	RecName: Full=Reverse gyrase {ECO:0000256|HAMAP-Rule:MF_01125, ECO:0000256|RuleBase:RU004026};	24.67	531	312	19	82	581	791	1264	2e-15	91.3
rs:WP_045970886	DNA topoisomerase I [Xenorhabdus doucetiae].	22.92	528	322	17	187	673	190	673	2e-15	90.9
rs:WP_038259937	DNA topoisomerase I [Xenorhabdus cabanillasii].	22.73	528	323	20	187	673	190	673	2e-15	90.9
rs:WP_025011036	DNA topoisomerase I [Shewanella algae].	22.68	613	364	21	74	633	88	643	2e-15	90.9
gp:AF088896_23	topoisomerase I [Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821]	23.16	678	413	26	1	629	6	624	2e-15	90.9
rs:WP_035423519	DNA topoisomerase I [Lactobacillus fermentum].	23.72	662	407	29	2	629	27	624	2e-15	90.5
rs:WP_021759761	DNA topoisomerase I [Desulfovibrio gigas].	22.73	682	410	24	3	639	5	614	2e-15	90.5
rs:WP_042677941	DNA topoisomerase I, partial [Pantoea sp. B40].	22.63	517	329	17	191	673	3	482	2e-15	90.5
rs:WP_041904771	DNA topoisomerase I, partial [Latescibacteria bacterium SCGC AAA252-B13].	26.31	498	289	18	77	536	54	511	2e-15	90.1
tr:A0A088TKF3_9MOLU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.26	577	347	21	90	629	69	592	2e-15	90.5
rs:XP_010316521	PREDICTED: uncharacterized protein LOC101248941 isoform X1 [Solanum lycopersicum].	27.13	516	308	24	64	536	410	900	2e-15	90.9
rs:WP_012351072	DNA topoisomerase [Pyrobaculum neutrophilum].	21.96	633	412	23	1	594	1	590	2e-15	90.1
rs:WP_021866070	DNA topoisomerase [Eubacterium sp. CAG:86].	23.39	560	357	18	90	616	67	587	2e-15	90.5
rs:WP_034096476	MULTISPECIES: DNA topoisomerase I [Pseudomonas fluorescens group].	23.47	473	306	13	187	633	197	639	2e-15	90.9
rs:WP_016803628	topoisomerase I [Acinetobacter nosocomialis].	23.53	595	368	19	74	629	100	646	2e-15	90.9
tr:A0A0D2D362_9EURO	SubName: Full=Strain CBS 72588 unplaced genomic scaffold supercont1.11, whole genome shotgun sequence {ECO:0000313|EMBL:KIW37743.1};	22.75	633	402	22	3	584	7	603	2e-15	90.1
rs:WP_011526737	DNA topoisomerase I [Lawsonia intracellularis].	25.22	579	357	22	89	629	63	603	2e-15	90.5
rs:WP_042082558	DNA topoisomerase I [Aeromonas veronii].	23.76	606	365	23	75	633	82	637	2e-15	90.9
rs:WP_004659079	DNA topoisomerase I [Acinetobacter sp. NIPH 236].	23.32	579	357	19	90	629	117	647	2e-15	90.9
tr:D0DRB1_LACFE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.72	662	407	29	2	629	25	622	2e-15	90.5
rs:XP_009215138	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Papio anubis].	24.52	416	262	13	188	585	76	457	2e-15	90.5
rs:WP_003003886	DNA topoisomerase I [Sphingobacterium spiritivorum].	24.79	476	294	15	76	526	53	489	2e-15	90.5
tr:C3AXE7_BACMY	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:EEM01684.1};	29.06	234	159	6	351	580	16	246	2e-15	87.0
rs:WP_039790467	DNA topoisomerase III, partial [Paenibacillus riograndensis].	34.59	159	96	5	76	230	1	155	2e-15	85.9
rs:WP_011994517	reverse gyrase [Fervidobacterium nodosum].	23.78	572	319	23	3	538	586	1076	2e-15	90.9
rs:WP_036486938	DNA topoisomerase I, partial [Myxosarcina sp. GI1].	25.35	572	354	19	76	614	57	588	2e-15	90.1
rs:WP_016396514	DNA topoisomerase I [Lactobacillus delbrueckii].	22.89	568	377	17	90	629	10	544	2e-15	90.1
rs:XP_010380073	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Rhinopithecus roxellana].	24.52	416	262	13	188	585	76	457	2e-15	90.5
rs:WP_031421645	DNA topoisomerase I [Exiguobacterium sp. NG55].	22.94	667	414	25	3	630	5	610	2e-15	90.5
rs:WP_029453258	DNA topoisomerase I [Clostridium algidicarnis].	23.76	564	363	16	83	616	60	586	2e-15	90.5
rs:WP_010768602	DNA topoisomerase 1 [Enterococcus phoeniculicola].	25.09	570	354	23	103	635	81	614	2e-15	90.5
rs:WP_012803306	DNA topoisomerase [Cryptobacterium curtum].	22.94	571	339	22	90	616	135	648	2e-15	90.5
rs:WP_007891355	DNA topoisomerase I [Streptococcus pseudoporcinus].	22.28	579	378	22	83	629	83	621	2e-15	90.5
rs:WP_008554385	DNA topoisomerase I [Rhodobacterales bacterium Y4I].	23.53	646	395	25	55	630	27	643	2e-15	90.9
rs:WP_008354502	DNA topoisomerase I [Bacillus xiamenensis].	23.84	562	369	21	105	636	82	614	2e-15	90.5
rs:XP_011738036	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Macaca nemestrina].	24.52	416	262	13	188	585	76	457	2e-15	90.5
rs:WP_023004052	MULTISPECIES: DNA topoisomerase I [Labrenzia].	24.44	622	367	27	1	574	1	567	2e-15	90.9
rs:WP_004712146	topoisomerase I [Yersinia frederiksenii].	22.80	649	397	20	74	673	86	679	2e-15	90.9
rs:WP_010962038	DNA topoisomerase I [Methylococcus capsulatus].	22.55	745	441	31	3	682	5	678	2e-15	90.5
rs:WP_032863314	DNA topoisomerase I [Pseudomonas sp. FH4].	23.16	475	307	14	186	633	196	639	2e-15	90.9
rs:WP_022425806	DNA topoisomerase [Catenibacterium sp. CAG:290].	23.73	670	392	31	3	629	4	597	2e-15	90.5
rs:WP_047227206	DNA topoisomerase I [Pseudomonas brassicacearum].	23.69	477	302	15	186	633	196	639	2e-15	90.5
rs:WP_029646111	DNA topoisomerase I, partial [Helicobacter pylori].	24.44	491	323	16	75	536	46	517	2e-15	89.7
rs:WP_038233626	DNA topoisomerase I [Xenorhabdus szentirmaii].	22.96	527	323	17	187	673	191	674	2e-15	90.5
rs:WP_041874370	hypothetical protein, partial [Microgenomates bacterium SCGC AAA011-A19].	24.21	698	390	26	1	629	1	628	2e-15	90.5
rs:WP_034808918	DNA topoisomerase I [Exiguobacterium sp. AB2].	22.74	664	417	27	3	629	5	609	2e-15	90.5
rs:WP_011179396	DNA topoisomerase I [Bartonella quintana].	22.64	698	406	27	1	629	1	633	2e-15	90.5
rs:WP_040154704	DNA topoisomerase III, partial [Klebsiella pneumoniae].	27.27	242	161	6	245	471	47	288	2e-15	87.4
rs:WP_045282656	DNA topoisomerase I [Shewanella algae].	22.68	613	364	21	74	633	88	643	2e-15	90.5
rs:WP_007375380	DNA topoisomerase I [Pseudoalteromonas sp. Bsw20308].	22.93	593	378	19	76	631	91	641	2e-15	90.9
rs:WP_038467628	DNA topoisomerase I [Mollicutes bacterium HR1].	24.26	577	347	21	90	629	70	593	2e-15	90.5
rs:WP_016971417	topoisomerase I [Pseudomonas tolaasii].	23.74	476	303	14	186	633	196	639	2e-15	90.5
rs:WP_013975679	topoisomerase I [Candidatus Moranella endobia].	24.27	478	310	14	74	533	72	515	2e-15	90.5
rs:WP_039700276	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	23.09	485	307	14	74	533	85	528	2e-15	90.1
rs:WP_037441137	DNA topoisomerase I [Sphingobacterium antarcticum].	23.86	528	326	17	77	578	54	531	2e-15	90.5
rs:WP_025738670	DNA topoisomerase I [Salinivibrio socompensis].	24.29	597	372	23	75	633	85	639	2e-15	90.5
rs:WP_015672512	DNA topoisomerase I [Serratia marcescens].	23.97	609	360	20	74	633	82	636	2e-15	90.5
rs:XP_005745891	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X2 [Pundamilia nyererei].	21.84	618	380	21	3	564	5	575	2e-15	90.5
rs:WP_026945101	DNA topoisomerase I [Algoriphagus marincola].	25.44	507	315	15	31	520	18	478	2e-15	90.5
rs:WP_031834052	DNA topoisomerase III, partial [Staphylococcus aureus].	26.47	272	185	5	355	620	23	285	2e-15	88.2
rs:WP_028152767	DNA topoisomerase I [Bradyrhizobium japonicum].	22.89	686	419	23	1	630	1	632	2e-15	90.5
rs:WP_003048468	DNA topoisomerase I [Streptococcus canis].	22.97	566	350	21	103	629	103	621	2e-15	90.5
rs:WP_015547003	DNA topoisomerase I [Alistipes shahii].	24.35	538	325	19	3	520	5	480	2e-15	90.5
rs:XP_008728657	hypothetical protein G647_06111 [Cladophialophora carrionii CBS 160.54].	23.56	539	329	17	90	584	105	604	2e-15	90.1
rs:WP_012424370	DNA topoisomerase I [Clostridium botulinum].	23.88	603	380	23	103	671	80	637	2e-15	90.5
rs:WP_046475920	DNA topoisomerase I [Filomicrobium sp. W].	23.66	655	388	27	55	630	27	648	2e-15	90.5
rs:WP_010334238	DNA topoisomerase I [Bacillus mojavensis].	23.82	571	367	22	105	641	82	618	2e-15	90.5
rs:WP_026559364	DNA topoisomerase I [Bacillus sp. J37].	22.86	560	375	20	105	635	82	613	2e-15	90.5
rs:WP_045092549	DNA topoisomerase I [Clostridium sp. FS41].	23.91	573	345	20	90	616	67	594	2e-15	90.5
rs:WP_031454641	DNA topoisomerase I [Flavobacterium chungangense].	23.74	674	419	24	3	659	5	600	2e-15	90.5
tr:C4V2Y3_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.77	589	379	20	83	636	102	655	2e-15	90.5
rs:WP_008942315	MULTISPECIES: topoisomerase I [Acinetobacter].	23.53	578	357	18	90	629	117	647	2e-15	90.5
rs:WP_028835835	MULTISPECIES: DNA topoisomerase I [Pseudoalteromonas].	22.71	612	391	21	60	631	72	641	2e-15	90.5
rs:WP_042832016	DNA topoisomerase III, partial [Xanthomonas citri].	28.31	219	142	6	188	391	16	234	2e-15	87.0
tr:C5ZW76_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.14	657	381	25	3	615	6	582	2e-15	90.5
rs:WP_039980895	DNA topoisomerase I [Selenomonas sp. oral taxon 149].	22.83	587	387	18	83	636	88	641	2e-15	90.5
tr:A0A0A8VIQ6_YERRU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.36	608	365	20	74	633	61	615	2e-15	90.5
rs:WP_025850763	DNA topoisomerase I [Paenibacillus ehimensis].	23.85	587	379	22	88	636	62	618	2e-15	90.1
rs:WP_020054580	hypothetical protein [alpha proteobacterium SCGC AAA015-N04].	24.60	683	403	28	1	629	1	625	2e-15	90.5
rs:WP_035791091	DNA topoisomerase I [Clostridium botulinum].	24.13	543	347	19	103	616	80	586	2e-15	90.1
rs:WP_007082332	DNA topoisomerase I [Rhodanobacter fulvus].	23.90	502	317	13	77	538	54	530	2e-15	90.5
rs:WP_012616618	DNA topoisomerase I [Chloroflexus aggregans].	23.06	581	360	16	83	612	58	602	2e-15	90.5
rs:WP_027698447	DNA topoisomerase I [Weissella oryzae].	23.03	660	414	26	3	629	26	624	2e-15	90.1
rs:WP_017729828	hypothetical protein [Nafulsella turpanensis].	25.08	602	349	24	3	578	5	530	2e-15	90.5
rs:WP_004285786	DNA topoisomerase I [Neisseria weaveri].	21.90	726	461	24	3	679	5	673	2e-15	90.5
rs:WP_021067110	MULTISPECIES: DNA topoisomerase I [Exiguobacterium].	22.39	661	425	25	3	630	5	610	2e-15	90.1
rs:XP_005670970	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Sus scrofa].	24.88	414	263	13	188	585	76	457	2e-15	90.5
rs:WP_028587743	DNA topoisomerase I [Desulfocurvus vexinensis].	23.36	685	405	25	3	640	5	616	2e-15	90.5
rs:WP_019791054	DNA topoisomerase I, partial [Streptococcus sobrinus].	23.55	535	338	19	83	589	87	578	2e-15	90.1
rs:WP_038625919	DNA topoisomerase I [Pantoea sp. PSNIH2].	23.16	475	307	12	187	633	187	631	2e-15	90.5
rs:WP_043804823	DNA topoisomerase I, partial [Deinococcus gobiensis].	25.24	420	252	12	189	574	173	564	2e-15	89.7
rs:XP_007953639	PREDICTED: DNA topoisomerase 3-beta-1 [Orycteropus afer afer].	24.58	415	263	13	188	585	201	582	2e-15	90.5
rs:XP_009005663	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Callithrix jacchus].	24.40	414	265	12	188	585	76	457	2e-15	90.1
rs:WP_035157700	DNA topoisomerase I [Lactobacillus reuteri].	24.61	577	356	25	90	629	86	620	2e-15	90.1
rs:WP_009661275	DNA topoisomerase I [Veillonella sp. ACP1].	23.37	569	364	23	95	629	135	665	2e-15	90.5
rs:WP_005083647	DNA topoisomerase I [Acinetobacter haemolyticus].	23.53	578	357	18	90	629	117	647	2e-15	90.5
rs:WP_039180480	DNA topoisomerase I [Leisingera sp. ANG-M7].	23.11	701	410	30	1	630	1	643	2e-15	90.5
rs:WP_008617440	DNA topoisomerase I [Paraprevotella clara].	23.17	600	369	20	3	580	5	534	2e-15	90.5
rs:WP_041914241	DNA topoisomerase I [Selenomonas ruminantium].	24.95	553	359	19	90	616	89	611	2e-15	90.5
rs:WP_038622494	DNA topoisomerase I [Dyella jiangningensis].	22.84	578	352	18	3	538	5	530	2e-15	90.5
rs:WP_008134073	MULTISPECIES: topoisomerase I [Pseudoalteromonas].	23.40	594	374	20	76	631	91	641	2e-15	90.5
rs:WP_003290000	topoisomerase I [Pseudomonas stutzeri].	22.88	472	308	11	186	631	193	634	2e-15	90.5
rs:WP_022853525	DNA topoisomerase I [Thermodesulfatator atlanticus].	24.17	575	339	20	100	629	77	599	2e-15	90.1
rs:WP_024771719	DNA topoisomerase I [Aquimarina macrocephali].	26.35	444	284	14	94	526	71	482	2e-15	90.5
rs:WP_018428142	DNA topoisomerase I [Hoeflea sp. 108].	22.52	635	405	24	55	630	27	633	2e-15	90.5
rs:WP_016268924	MULTISPECIES: DNA topoisomerase I [Bacteroides].	23.29	541	340	17	3	526	5	487	2e-15	90.5
rs:WP_022361564	GTP-sensing transcriptional pleiotropic repressor CodY [Bacteroides pectinophilus CAG:437].	24.56	566	345	20	90	616	67	589	2e-15	90.1
rs:WP_003622318	DNA topoisomerase I [Komagataeibacter hansenii].	21.02	685	433	26	3	630	4	637	2e-15	90.5
rs:WP_033039332	DNA topoisomerase I [Pseudoalteromonas sp. S3431].	23.40	594	374	20	76	631	91	641	2e-15	90.5
rs:WP_024953298	DNA topoisomerase I [Cobetia crustatorum].	23.86	591	376	20	76	633	94	643	2e-15	90.5
rs:WP_041020100	DNA topoisomerase I [Pseudomonas sp. SHC52].	23.69	477	302	15	186	633	196	639	2e-15	90.5
rs:WP_020223114	DNA topoisomerase I [Holdemania massiliensis].	24.04	674	391	28	3	629	4	603	2e-15	90.1
tr:A7HLU3_FERNB	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.21	661	395	25	2	631	41	626	2e-15	90.1
rs:WP_043391541	DNA topoisomerase I [Cystobacter violaceus].	22.37	693	426	27	3	640	88	723	3e-15	90.5
rs:WP_015881378	DNA topoisomerase I [Exiguobacterium sp. AT1b].	22.79	667	415	25	3	630	5	610	3e-15	90.1
rs:WP_015006903	MULTISPECIES: DNA topoisomerase I [Cycloclasticus].	24.45	687	389	29	3	630	4	619	3e-15	90.1
rs:WP_013194217	DNA topoisomerase [Methanohalobium evestigatum].	23.54	616	377	22	46	614	52	620	3e-15	90.1
rs:WP_003717034	DNA topoisomerase I [Lactobacillus vaginalis].	23.65	668	400	27	2	629	25	622	3e-15	90.1
rs:WP_006655377	DNA topoisomerase I [Helicobacter canadensis].	22.83	657	383	24	3	615	4	580	3e-15	90.1
rs:WP_008237824	DNA topoisomerase I [Imtechella halotolerans].	24.53	530	332	16	3	521	5	477	3e-15	90.5
rs:WP_035784394	DNA topoisomerase I [Clostridium botulinum].	24.13	543	347	19	103	616	80	586	3e-15	90.1
rs:WP_005315206	DNA topoisomerase I [Acinetobacter sp. ANC 3880].	23.53	578	357	18	90	629	117	647	3e-15	90.5
rs:WP_036982852	DNA topoisomerase I [Pseudoalteromonas sp. SCSIO_11900].	22.88	612	390	22	60	631	72	641	3e-15	90.5
rs:WP_018458334	DNA topoisomerase I [Bradyrhizobium sp. WSM4349].	22.95	706	428	25	1	647	1	649	3e-15	90.5
rs:WP_022747953	DNA topoisomerase I [Lachnobacterium bovis].	23.28	640	392	20	90	659	67	677	3e-15	90.1
tr:T3QTH0_PEPDI	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EQG76222.1};	38.58	127	63	5	1	119	1	120	3e-15	84.3
rs:WP_009534199	DNA topoisomerase I [Oribacterium parvum].	22.93	641	410	20	3	616	5	588	3e-15	90.1
rs:WP_028035012	DNA topoisomerase I [Chelativorans sp. J32].	22.00	700	409	27	1	630	1	633	3e-15	90.5
rs:XP_008219962	PREDICTED: uncharacterized protein LOC103320114 [Prunus mume].	23.80	605	371	27	64	610	406	978	3e-15	90.5
rs:WP_014389293	DNA topoisomerase I [Flavobacterium indicum].	24.15	617	386	22	3	602	5	556	3e-15	90.5
rs:WP_026474023	DNA topoisomerase I [Alkaliflexus imshenetskii].	24.68	539	328	18	1	520	10	489	3e-15	90.1
rs:WP_013930323	DNA topoisomerase I [Runella slithyformis].	24.49	539	334	17	3	526	5	485	3e-15	90.1
rs:WP_032027328	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	3e-15	90.5
rs:WP_031961607	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	3e-15	90.5
tr:A0A090RC47_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.42	240	151	6	101	325	1	239	3e-15	86.7
rs:WP_028892457	DNA topoisomerase I [Tenacibaculum sp. 47A_GOM-205m].	27.15	372	238	10	157	521	132	477	3e-15	90.1
rs:WP_005200284	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	23.53	578	357	18	90	629	117	647	3e-15	90.5
rs:XP_012321903	PREDICTED: DNA topoisomerase 3-beta-1 isoform X5 [Aotus nancymaae].	24.40	414	265	12	188	585	76	457	3e-15	90.1
rs:WP_040155054	DNA topoisomerase I [Yersinia ruckeri].	23.36	608	365	20	74	633	86	640	3e-15	90.5
rs:WP_009082009	DNA topoisomerase I [Peptostreptococcaceae bacterium AS15].	24.79	597	356	24	83	635	59	606	3e-15	90.1
rs:WP_016675323	hypothetical protein, partial [Yersinia pestis].	36.52	115	67	3	1	113	1	111	3e-15	84.7
rs:WP_013439705	DNA topoisomerase I [Lactobacillus delbrueckii].	22.92	554	364	17	90	616	97	614	3e-15	90.1
rs:WP_005291614	DNA topoisomerase I [Acinetobacter sp. NIPH 2100].	23.14	579	358	19	90	629	117	647	3e-15	90.5
rs:WP_005303279	MULTISPECIES: topoisomerase I [Aeromonas].	23.76	606	365	22	75	633	82	637	3e-15	90.5
rs:WP_027259853	DNA topoisomerase I [Leisingera aquimarina].	22.50	649	373	22	1	587	1	581	3e-15	90.5
rs:WP_009162132	DNA topoisomerase I [Prevotella saccharolytica].	23.55	603	359	20	3	578	5	532	3e-15	90.1
rs:WP_004644771	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	24.09	523	347	16	32	537	16	505	3e-15	90.1
rs:WP_031588933	DNA topoisomerase I [Kandleria vitulina].	23.00	661	408	24	3	629	4	597	3e-15	90.1
rs:WP_004637808	topoisomerase I [Acinetobacter haemolyticus].	23.53	578	357	18	90	629	117	647	3e-15	90.5
rs:WP_024891862	DNA topoisomerase I [Luteimonas huabeiensis].	23.05	590	368	19	100	638	77	631	3e-15	90.1
rs:WP_043851335	DNA topoisomerase I [Aeromonas sp. L_1B5_3].	23.93	606	364	23	75	633	82	637	3e-15	90.1
rs:WP_044785597	DNA topoisomerase I [Paenibacillus polymyxa].	23.32	566	372	20	103	636	80	615	3e-15	90.1
rs:WP_018197579	MULTISPECIES: hypothetical protein [unclassified Cloacimonetes].	25.59	590	351	21	83	629	60	604	3e-15	90.1
rs:WP_043149963	DNA topoisomerase I [Sphingobium sp. Ant17].	21.01	671	431	23	1	629	1	614	3e-15	90.1
rs:WP_009209696	DNA topoisomerase I [Aurantimonas manganoxydans].	22.68	710	421	31	1	643	1	649	3e-15	90.5
rs:WP_009812653	DNA topoisomerase I [Roseovarius nubinhibens].	23.99	567	339	20	1	534	1	508	3e-15	90.1
rs:WP_007858081	DNA topoisomerase I [[Clostridium] citroniae].	23.91	573	345	20	90	616	67	594	3e-15	90.1
rs:WP_002850920	DNA topoisomerase I [Campylobacter fetus].	24.13	518	312	20	100	578	72	547	3e-15	89.7
rs:WP_007174734	DNA topoisomerase I [Prevotella bergensis].	26.42	405	239	12	3	392	5	365	3e-15	90.1
rs:WP_036888796	DNA topoisomerase I [Prevotella aurantiaca].	22.91	633	388	20	3	605	24	586	3e-15	90.1
rs:WP_027573622	DNA topoisomerase I [Bradyrhizobium sp. WSM1743].	23.30	704	428	24	1	647	1	649	3e-15	90.5
rs:WP_038004586	MULTISPECIES: DNA topoisomerase I [Thalassobacter].	24.37	513	324	16	55	534	27	508	3e-15	90.1
tr:A0A015VLW3_BACFG	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EXY86863.1}; Flags: Fragment;	28.34	187	116	5	1	176	1	180	3e-15	85.5
rs:WP_014873719	DNA topoisomerase I [Phaeobacter gallaeciensis].	23.32	579	348	20	1	534	1	528	3e-15	90.1
rs:WP_027247922	DNA topoisomerase I [Phaeobacter inhibens].	23.32	579	348	20	1	534	1	528	3e-15	90.1
rs:WP_009632516	DNA topoisomerase I [Synechocystis sp. PCC 7509].	23.00	626	374	18	3	574	4	575	3e-15	90.1
rs:NP_001167403	DNA topoisomerase 3-beta-1 [Salmo salar].	23.37	612	378	23	3	564	5	575	3e-15	90.1
rs:WP_010474526	DNA topoisomerase I [Acaryochloris sp. CCMEE 5410].	23.47	639	378	22	3	584	4	588	3e-15	90.1
rs:WP_036778667	DNA topoisomerase I [Pontibacillus chungwhensis].	22.52	564	374	19	105	635	82	615	3e-15	90.1
rs:WP_021510115	topoisomerase I [Pantoea dispersa].	23.14	484	296	15	187	633	190	634	3e-15	90.1
rs:WP_032577270	DNA topoisomerase I, partial [Bacteroides fragilis].	28.34	187	116	5	1	176	10	189	3e-15	85.5
rs:XP_009005657	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Callithrix jacchus].	24.40	414	265	12	188	585	88	469	3e-15	90.1
rs:WP_016508253	DNA topoisomerase I [Exiguobacterium sp. S17].	22.44	664	421	27	3	630	5	610	3e-15	90.1
gpu:CP011489_224	DNA topoisomerase I, bacterial [Actinobacteria bacterium IMCC26256]	24.43	569	326	25	19	530	5	526	3e-15	90.1
rs:WP_039926969	DNA topoisomerase I [Leptospira vanthielii].	23.04	473	312	9	87	536	48	491	3e-15	89.7
rs:WP_034346907	DNA topoisomerase I [Helicobacter trogontum].	23.76	627	381	27	55	629	24	605	3e-15	90.1
rs:WP_028780491	DNA topoisomerase I [Shewanella sp. 38A_GOM-205m].	22.68	613	364	21	74	633	88	643	3e-15	90.1
rs:WP_009372033	DNA topoisomerase I [Veillonella sp. oral taxon 158].	22.97	579	354	21	95	629	98	628	3e-15	90.1
rs:WP_000655395	DNA topoisomerase I [Helicobacter pylori].	24.59	492	321	14	75	536	46	517	3e-15	89.7
rs:WP_016820944	DNA topoisomerase I [Paenibacillus polymyxa].	23.32	566	372	20	103	636	80	615	3e-15	90.1
rs:WP_046559052	DNA topoisomerase I [Arsukibacterium ikkense].	22.99	683	386	27	60	673	59	670	3e-15	90.1
rs:WP_035184592	DNA topoisomerase I [Lactobacillus delbrueckii].	22.85	569	378	17	90	630	97	632	3e-15	90.1
rs:WP_022941114	topoisomerase I [Psychromonas hadalis].	25.72	486	282	19	187	633	198	643	3e-15	90.1
rs:WP_028830031	DNA topoisomerase I [Proteocatella sphenisci].	24.22	574	337	19	90	616	68	590	3e-15	90.1
rs:WP_037150123	DNA topoisomerase I [Rhizobium sp. YS-1r].	22.47	663	414	26	32	630	10	636	3e-15	90.1
rs:WP_036858196	hypothetical protein, partial [Prevotella amnii].	31.79	195	98	6	239	414	32	210	3e-15	85.9
rs:WP_011077240	DNA topoisomerase I [Mycoplasma penetrans].	23.54	582	344	19	103	629	88	623	3e-15	90.1
tr:A0A0D2HCU3_9EURO	SubName: Full=Unplaced genomic scaffold supercont1.12, whole genome shotgun sequence {ECO:0000313|EMBL:KIW91083.1};	22.78	654	399	24	3	593	7	617	3e-15	89.7
tr:A0A0B8VBY9_9PSED	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGS11352.1}; Flags: Fragment;	25.09	271	180	6	432	684	3	268	3e-15	86.7
rs:XP_001771420	predicted protein, partial [Physcomitrella patens].	22.79	531	344	16	77	563	52	560	3e-15	89.7
rs:WP_032035863	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	3e-15	90.1
rs:WP_025673753	DNA topoisomerase I [Salinivibrio socompensis].	23.97	605	364	22	75	633	85	639	3e-15	90.1
rs:WP_032058555	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	3e-15	90.1
tr:H8H1G5_DEIGI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.59	426	254	13	189	579	173	570	3e-15	89.7
rs:WP_044172924	DNA topoisomerase I, partial [Oscillatoria sp. PCC 10802].	24.95	541	321	14	81	578	62	560	3e-15	89.7
rs:WP_016899533	topoisomerase I [Pseudoalteromonas sp. PAMC 22718].	22.88	612	390	22	60	631	72	641	3e-15	90.1
rs:WP_027827406	DNA topoisomerase I [Lactobacillus harbinensis].	24.10	585	366	21	90	635	67	612	3e-15	89.7
tr:S6PVT2_PSESF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	23.79	475	302	14	187	633	69	511	3e-15	90.1
rs:WP_033746803	DNA topoisomerase I [Pantoea sp. NGS-ED-1003].	23.83	600	372	21	74	633	80	634	3e-15	90.1
rs:WP_028387468	DNA topoisomerase I [Legionella geestiana].	22.98	657	397	29	55	649	29	638	3e-15	90.1
rs:WP_038702721	hypothetical protein, partial [Sphingobacterium sp. ML3W].	24.51	510	321	16	31	520	18	483	3e-15	90.1
rs:WP_045391379	DNA topoisomerase I [Falsirhodobacter sp. alg1].	22.52	715	433	29	1	659	1	650	3e-15	90.1
rs:WP_022269185	DNA topoisomerase [Firmicutes bacterium CAG:424].	24.35	464	282	12	187	616	161	589	3e-15	89.7
rs:WP_015853669	DNA topoisomerase I [Desulfovibrio salexigens].	22.39	679	415	23	3	640	5	612	3e-15	90.1
rs:WP_025796828	DNA topoisomerase I [Prevotella saccharolytica].	23.80	605	355	21	3	578	5	532	3e-15	90.1
rs:WP_033102497	MULTISPECIES: DNA topoisomerase I [Alteromonadales].	22.88	612	390	22	60	631	72	641	3e-15	90.1
rs:WP_011468263	topoisomerase I [Saccharophagus degradans].	23.24	611	373	23	65	629	80	640	3e-15	90.1
rs:WP_042524917	DNA topoisomerase I [Yersinia ruckeri].	23.19	608	366	19	74	633	86	640	3e-15	90.1
rs:WP_033136942	DNA topoisomerase I [Aeromonas sp. 4287D].	23.76	606	365	23	75	633	82	637	3e-15	90.1
rs:WP_035132778	DNA topoisomerase I [Clostridium sulfidigenes].	24.27	647	396	20	2	616	4	588	3e-15	89.7
rs:WP_031979792	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	3e-15	90.1
rs:WP_016704946	topoisomerase I [Pseudomonas chlororaphis].	22.57	474	311	12	186	633	196	639	3e-15	90.1
rs:WP_039073950	DNA topoisomerase I [Bacillus sp. MSP13].	23.14	566	379	20	105	642	82	619	3e-15	89.7
rs:WP_007546838	DNA topoisomerase I [Sulfurihydrogenibium yellowstonense].	26.09	548	346	17	2	537	5	505	3e-15	89.7
rs:WP_018604863	DNA topoisomerase I [Pseudomonas sp. CFII68].	23.69	477	302	15	186	633	196	639	3e-15	90.1
rs:XP_007196359	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Balaenoptera acutorostrata scammoni].	25.60	414	260	14	188	585	76	457	3e-15	89.7
rs:WP_042007188	DNA topoisomerase I [Aeromonas dhakensis].	23.76	606	365	22	75	633	82	637	3e-15	90.1
rs:WP_028531204	MULTISPECIES: DNA topoisomerase I [Paenibacillus].	22.94	571	368	20	103	636	80	615	3e-15	89.7
rs:XP_006341743	PREDICTED: DNA topoisomerase 3-alpha-like [Solanum tuberosum].	24.23	652	380	26	3	592	12	611	3e-15	90.1
rs:WP_015391419	DNA topoisomerase 1 [Clostridium saccharoperbutylacetonicum].	23.24	654	392	26	2	616	4	586	3e-15	89.7
rs:WP_014879262	DNA topoisomerase I [Phaeobacter inhibens].	23.32	579	348	20	1	534	1	528	3e-15	90.1
rs:WP_046552789	DNA topoisomerase I [Arsukibacterium sp. MJ3].	22.71	665	410	23	60	673	59	670	3e-15	90.1
rs:WP_002888489	DNA topoisomerase I [Streptococcus salivarius].	22.95	562	356	22	103	630	108	626	3e-15	89.7
rs:WP_042051062	MULTISPECIES: DNA topoisomerase I [Aeromonas].	23.76	606	365	22	75	633	82	637	3e-15	90.1
rs:WP_018704610	hypothetical protein [Anaeromusa acidaminophila].	22.78	641	410	19	3	615	4	587	3e-15	89.7
rs:WP_022053984	DNA topoisomerase [Bacteroides plebeius CAG:211].	23.03	534	345	14	3	526	5	482	3e-15	90.1
rs:WP_021973169	DNA topoisomerase [Eubacterium sp. CAG:180].	22.60	655	408	25	2	616	3	598	3e-15	89.7
rs:WP_020366332	DNA topoisomerase III, partial [Staphylococcus epidermidis].	32.61	184	115	4	436	615	30	208	3e-15	87.0
rs:WP_012861272	DNA topoisomerase I [Sebaldella termitidis].	24.96	633	369	21	2	604	4	560	3e-15	89.7
rs:WP_013944621	DNA topoisomerase I [Simkania negevensis].	23.09	576	370	17	82	614	63	608	3e-15	90.1
rs:WP_017737335	topoisomerase I [Pseudomonas sp. CBZ-4].	23.21	474	308	13	186	633	196	639	3e-15	90.1
rs:WP_045850104	DNA topoisomerase I [Domibacillus enclensis].	23.20	556	367	19	105	630	82	607	3e-15	89.7
rs:WP_015863217	DNA topoisomerase I [Desulfovibrio magneticus].	24.08	652	382	29	76	669	53	649	3e-15	89.7
tr:A0A0D6NH25_9PROT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAN65362.1};	22.22	639	402	22	55	630	28	634	3e-15	90.1
rs:WP_013729958	DNA topoisomerase I [Mycoplasma mycoides].	24.22	611	365	26	61	625	47	605	3e-15	89.7
rs:WP_008765309	MULTISPECIES: DNA topoisomerase I [Bacteroides].	23.29	541	340	17	3	526	5	487	3e-15	89.7
rs:WP_042020602	DNA topoisomerase I [Aeromonas sobria].	22.81	605	372	20	75	633	82	637	3e-15	90.1
rs:XP_009367980	PREDICTED: uncharacterized protein LOC103957527 isoform X1 [Pyrus x bretschneideri].	22.88	612	389	24	64	618	407	992	3e-15	90.1
rs:WP_025212749	DNA topoisomerase I [Pseudomonas brassicacearum].	23.69	477	302	15	186	633	196	639	3e-15	90.1
rs:WP_035325402	DNA topoisomerase I [Dokdonia donghaensis].	25.65	538	316	20	3	521	5	477	3e-15	90.1
rs:WP_024585500	DNA topoisomerase I [Aliihoeflea sp. 2WW].	23.19	690	415	33	1	630	1	635	3e-15	90.1
tr:A0A075G8L8_9EURY	SubName: Full=DNA topoisomerase I (TopA) {ECO:0000313|EMBL:AIE98072.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AIE98072.1};	24.30	539	314	23	89	574	74	571	3e-15	89.7
rs:WP_002645950	DNA topoisomerase I [Planctomyces maris].	23.04	625	403	18	77	655	73	665	3e-15	90.1
rs:WP_011498278	DNA topoisomerase I [Methanococcoides burtonii].	23.56	679	414	32	1	630	1	623	3e-15	89.7
rs:WP_042041488	DNA topoisomerase I [Aeromonas rivuli].	22.85	534	328	18	187	680	193	682	3e-15	90.1
tr:E0NXP6_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.83	587	387	18	83	636	102	655	3e-15	89.7
tr:A0A010EZ36_ACIBA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.49	596	363	19	76	629	79	623	3e-15	90.1
rs:WP_022744691	DNA topoisomerase 1 [Clostridium saccharobutylicum].	24.69	648	390	26	2	616	4	586	3e-15	89.7
rs:WP_025065595	DNA topoisomerase I [Prevotella enoeca].	24.58	594	366	20	3	578	5	534	3e-15	89.7
rs:WP_036227104	DNA topoisomerase I [Marmoricola sp. URHB0036].	23.72	662	378	25	2	591	9	615	3e-15	90.1
rs:WP_040445183	DNA topoisomerase I [[Eubacterium] yurii].	24.45	593	363	24	83	635	59	606	3e-15	89.7
rs:WP_032062207	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	3e-15	90.1
rs:WP_032025980	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	3e-15	90.1
rs:WP_026763856	DNA topoisomerase I [Sediminibacterium salmoneum].	25.69	545	327	20	3	528	5	490	4e-15	90.1
tr:Z2EWY0_VIBPH	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EVU20829.1}; Flags: Fragment;	30.81	185	115	6	2	179	3	181	4e-15	85.1
rs:WP_046819513	DNA topoisomerase I [Pseudomonas putida].	23.69	477	302	15	186	633	196	639	4e-15	90.1
rs:WP_031950010	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	4e-15	90.1
rs:WP_003183422	topoisomerase I [Pseudomonas fluorescens].	23.69	477	302	15	186	633	196	639	4e-15	90.1
rs:WP_004587792	DNA topoisomerase I subunit omega [Pseudoalteromonas agarivorans].	22.95	623	400	22	49	631	59	641	4e-15	90.1
rs:WP_031875549	DNA topoisomerase III, partial [Staphylococcus aureus].	35.33	167	95	5	3	164	4	162	4e-15	84.7
rs:XP_008788964	PREDICTED: uncharacterized protein LOC103706593 [Phoenix dactylifera].	24.43	524	311	20	64	536	339	828	4e-15	90.1
rs:WP_043696433	DNA topoisomerase I [Luteibacter sp. 9133].	24.15	410	246	13	163	536	142	522	4e-15	89.7
rs:WP_020843081	DNA topoisomerase I [Lactobacillus reuteri].	24.78	577	355	25	90	629	86	620	4e-15	89.7
rs:WP_022108248	DNA topoisomerase [Clostridium sp. CAG:138].	23.54	565	355	20	90	615	67	593	4e-15	89.7
tr:T0TYN3_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.95	562	356	22	103	630	23	541	4e-15	89.4
rs:WP_037392358	DNA topoisomerase I [Snodgrassella alvi].	21.99	673	417	25	3	630	5	614	4e-15	89.7
rs:WP_043243916	DNA topoisomerase I [Pseudomonas alcaligenes].	23.21	474	308	13	186	633	195	638	4e-15	89.7
rs:WP_017296559	hypothetical protein [Nodosilinea nodulosa].	22.29	637	379	22	76	641	56	647	4e-15	89.7
rs:WP_023846213	topoisomerase IA [Methanolobus tindarius].	22.59	726	447	29	3	670	4	672	4e-15	89.7
tr:E0QIP1_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.45	593	363	24	83	635	62	609	4e-15	89.7
rs:WP_010331111	DNA topoisomerase I [Bacillus vallismortis].	23.14	566	379	20	105	642	82	619	4e-15	89.7
rs:WP_020403880	hypothetical protein [Gracilimonas tropica].	25.76	528	309	18	96	573	86	580	4e-15	89.7
rs:WP_022046703	GTP-sensing transcriptional pleiotropic repressor CodY [Roseburia sp. CAG:18].	23.29	627	391	21	90	675	67	644	4e-15	89.7
tr:J1GV42_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.33	533	324	17	3	521	25	497	4e-15	89.7
rs:XP_004670830	PREDICTED: DNA topoisomerase 3-beta-1 [Jaculus jaculus].	22.70	630	399	22	3	585	5	593	4e-15	89.7
rs:WP_044330667	DNA topoisomerase I [Bacillus safensis].	23.98	563	367	22	105	636	82	614	4e-15	89.7
tr:A0A0C7P0Z4_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.60	569	345	20	103	631	81	605	4e-15	89.7
rs:WP_005992671	DNA topoisomerase I [Desulfovibrio fructosivorans].	24.19	645	390	27	76	669	53	649	4e-15	89.7
rs:WP_006797683	DNA topoisomerase I [Dysgonomonas gadei].	24.21	537	330	18	3	521	5	482	4e-15	89.7
rs:WP_044121391	DNA topoisomerase I, partial [Anaerobiospirillum succiniciproducens].	23.65	537	323	19	187	680	190	682	4e-15	89.7
rs:WP_008398460	MULTISPECIES: DNA topoisomerase I [Clostridium].	23.83	621	393	20	90	671	67	646	4e-15	89.7
rs:XP_002107874	hypothetical protein TRIADDRAFT_49643 [Trichoplax adhaerens].	23.64	605	381	21	3	564	5	571	4e-15	89.7
rs:WP_021139069	DNA topoisomerase I subunit omega [Aeromonas salmonicida].	23.60	606	366	22	75	633	82	637	4e-15	89.7
rs:WP_037031563	DNA topoisomerase I [Psychrobacter phenylpyruvicus].	24.61	646	390	25	77	673	97	694	4e-15	89.7
rs:WP_008238576	DNA topoisomerase I [Pedobacter sp. BAL39].	24.86	523	327	17	77	578	54	531	4e-15	89.7
rs:WP_041013033	hypothetical protein [Vibrio sp. DCR 1-4-12].	36.00	125	77	1	437	558	5	129	4e-15	85.1
rs:WP_037414251	DNA topoisomerase I [Sinorhizobium sp. CCBAU 05631].	22.80	693	415	28	1	630	1	636	4e-15	89.7
rs:WP_017660177	DNA topoisomerase I [Geitlerinema sp. PCC 7105].	25.36	619	371	24	3	577	4	575	4e-15	89.7
rs:WP_031959721	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	4e-15	89.7
tr:V2BAJ7_SALET	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	488	307	17	73	533	74	529	4e-15	89.0
rs:WP_027449291	DNA topoisomerase I [Prevotella brevis].	22.81	548	340	17	3	526	5	493	4e-15	89.7
rs:WP_038115136	DNA topoisomerase I [Veillonella sp. AS16].	22.65	574	362	21	95	629	143	673	4e-15	89.7
tr:Q7ZY67_XENLA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.56	416	266	12	188	585	52	433	4e-15	89.7
rs:WP_039126264	DNA topoisomerase I [Gilliamella apicola].	23.20	625	371	20	63	633	65	634	4e-15	89.7
rs:WP_005023286	MULTISPECIES: topoisomerase I [Acinetobacter].	23.70	595	363	20	76	629	104	648	4e-15	89.7
tr:T1I0Z0_RHOPR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.65	490	299	16	188	634	240	692	4e-15	89.7
rs:WP_031965029	DNA topoisomerase I [Acinetobacter baumannii].	23.49	596	367	20	75	629	99	646	4e-15	89.7
rs:WP_009161458	hypothetical protein, partial [Prevotella saccharolytica].	32.14	196	118	8	487	677	1	186	4e-15	85.5
rs:WP_005210345	DNA topoisomerase I [Acinetobacter sp. NIPH 1867].	23.32	579	357	19	90	629	117	647	4e-15	89.7
rs:WP_041876214	DNA topoisomerase I [Bdellovibrio sp. ArHS].	23.81	588	330	21	1	530	11	538	4e-15	89.7
tr:D8MSU2_ERWBE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.86	595	384	20	75	633	79	634	4e-15	89.7
rs:WP_025036761	DNA topoisomerase I [Bradyrhizobium sp. DOA9].	23.30	704	428	24	1	647	1	649	4e-15	89.7
rs:WP_028392863	DNA topoisomerase I [Bacillus sp. FJAT-14515].	23.09	563	370	22	105	635	82	613	4e-15	89.4
rs:WP_034554136	DNA topoisomerase I [Capnocytophaga sp. oral taxon 335].	24.86	535	324	16	3	521	5	477	4e-15	89.7
tr:G7I5R0_MEDTR	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	26.63	383	227	16	64	408	198	564	4e-15	89.7
rs:WP_019962158	DNA topoisomerase I [Woodsholea maritima].	22.30	695	406	28	1	629	1	627	4e-15	89.7
rs:WP_031966320	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	4e-15	89.7
rs:WP_004354064	DNA topoisomerase I [Prevotella denticola].	23.44	610	361	21	3	580	5	540	4e-15	89.7
rs:WP_020675223	hypothetical protein [Geopsychrobacter electrodiphilus].	21.34	703	448	23	3	654	5	653	4e-15	89.7
rs:WP_015078479	DNA topoisomerase I [Anabaena sp. 90].	25.13	581	348	21	79	610	59	601	4e-15	89.7
rs:WP_029087405	DNA topoisomerase I [Brevundimonas aveniformis].	24.34	567	338	23	1	534	1	509	4e-15	89.7
rs:WP_004513038	DNA topoisomerase I [Geobacter metallireducens].	22.70	727	420	31	3	658	5	660	4e-15	89.7
rs:WP_014633069	MULTISPECIES: DNA topoisomerase I [Streptococcus].	22.95	562	356	22	103	630	108	626	4e-15	89.4
rs:WP_021144079	DNA topoisomerase I [Streptococcus sp. HSISS1].	22.95	562	356	22	103	630	108	626	4e-15	89.4
rs:WP_023735323	DNA topoisomerase I [Mesorhizobium sp. LNJC399B00].	22.68	701	403	26	1	630	1	633	4e-15	89.7
tr:S9SZJ9_PAEAL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.94	571	368	20	103	636	54	589	4e-15	89.4
rs:WP_039562051	DNA topoisomerase I [Serpens flexibilis].	22.26	656	410	18	74	684	84	684	4e-15	89.7
rs:WP_027589307	DNA topoisomerase I [Pseudomonas sp. RL].	22.26	656	410	18	74	684	84	684	4e-15	89.7
rs:WP_037258583	DNA topoisomerase I [Roseivivax halodurans].	21.51	716	422	21	1	630	1	662	4e-15	89.7
rs:WP_029076598	DNA topoisomerase I [Kaistia adipata].	23.95	693	403	28	1	630	1	632	4e-15	89.7
rs:WP_017163892	DNA topoisomerase I, partial [Xanthomonas axonopodis].	25.30	411	246	15	163	538	36	420	4e-15	89.4
rs:WP_042029403	DNA topoisomerase I [Aeromonas jandaei].	23.93	606	364	23	75	633	82	637	4e-15	89.7
rs:WP_040661207	DNA topoisomerase I [Oscillibacter ruminantium].	22.81	627	411	20	90	680	68	657	4e-15	89.7
rs:WP_008142805	DNA topoisomerase I [Bacteroides coprophilus].	23.02	630	397	21	3	617	5	561	4e-15	89.7
rs:WP_026826260	DNA topoisomerase I [Exiguobacterium marinum].	22.64	667	416	25	3	630	5	610	4e-15	89.4
rs:WP_022278168	DNA topoisomerase [Bacteroides coprophilus CAG:333].	22.86	630	398	21	3	617	5	561	4e-15	89.7
tr:V8CQI8_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETD29285.1};	30.18	222	144	7	455	673	79	292	4e-15	86.7
rs:WP_033160278	DNA topoisomerase I [Mycoplasma alvi].	21.88	640	383	20	37	614	23	607	4e-15	89.4
rs:WP_043273977	DNA topoisomerase I [Pseudomonas sp. AAC].	23.57	560	355	16	88	615	77	595	4e-15	89.4
rs:WP_034260918	DNA topoisomerase I [Altibacter lentus].	26.08	556	335	23	3	539	5	503	4e-15	89.7
rs:WP_023688317	DNA topoisomerase I [Mesorhizobium sp. LSJC269B00].	22.68	701	403	26	1	630	1	633	4e-15	89.7
rs:WP_004698880	DNA topoisomerase I [Acinetobacter sp. NIPH 973].	23.36	595	369	19	74	629	100	646	4e-15	89.7
rs:WP_029639161	DNA topoisomerase I [alpha proteobacterium Mf 1.05b.01].	22.33	618	377	18	1	574	1	559	4e-15	89.7
rs:WP_000655394	DNA topoisomerase I [Helicobacter pylori].	24.39	492	322	13	75	536	46	517	4e-15	89.4
rs:WP_007163929	DNA topoisomerase I [Erythrobacter sp. NAP1].	21.36	735	459	26	1	681	1	670	4e-15	89.7
rs:WP_036676479	DNA topoisomerase I [Paenibacillus sp. MSt1].	23.82	592	373	22	88	636	62	618	4e-15	89.4
rs:WP_021746945	DNA topoisomerase I [Leptotrichia wadei].	24.03	620	365	19	2	587	4	551	4e-15	89.7
rs:WP_039883922	DNA topoisomerase I [Mogibacterium sp. CM50].	23.21	672	405	26	3	635	1	600	4e-15	89.4
rs:WP_021151812	DNA topoisomerase I [Streptococcus sp. HSISS3].	22.95	562	356	22	103	630	108	626	4e-15	89.4
rs:WP_035582537	DNA topoisomerase I [Hyphomonas jannaschiana].	23.72	624	388	26	1	592	1	568	4e-15	89.7
rs:WP_042890911	DNA topoisomerase I [Acinetobacter junii].	23.14	579	358	19	90	629	117	647	4e-15	89.7
tr:B1M8L6_METRJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.68	604	382	25	44	580	18	603	4e-15	89.7
rs:WP_035886894	DNA topoisomerase I [Legionella norrlandica].	24.90	518	325	16	55	534	29	520	4e-15	89.4
rs:WP_035135932	DNA topoisomerase I [Flavobacterium beibuense].	24.76	529	332	14	3	521	5	477	4e-15	89.7
rs:WP_043571895	DNA topoisomerase I [Chromobacterium subtsugae].	22.91	502	320	15	164	630	143	612	4e-15	89.4
rs:WP_013185913	DNA topoisomerase I [Croceibacter atlanticus].	26.21	538	313	19	3	521	5	477	4e-15	89.7
rs:XP_002162301	PREDICTED: DNA topoisomerase 3-like [Hydra vulgaris].	24.36	583	307	23	39	546	77	600	4e-15	89.7
rs:WP_027178311	DNA topoisomerase I [Desulfovibrio bastinii].	23.89	678	406	28	3	640	5	612	4e-15	89.7
rs:WP_027559642	MULTISPECIES: DNA topoisomerase I [Bradyrhizobium].	23.29	687	415	24	1	630	1	632	4e-15	89.7
rs:WP_005403630	topoisomerase I [Acinetobacter junii].	23.14	579	358	19	90	629	117	647	4e-15	89.7
rs:WP_026835620	DNA topoisomerase I [Eubacterium xylanophilum].	22.57	647	404	19	3	616	5	587	4e-15	89.4
rs:WP_044063641	hypothetical protein, partial [Prevotella saccharolytica].	37.50	128	63	3	1	117	1	122	4e-15	84.0
tr:A0A0A8VSW0_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.25	569	347	20	103	631	81	605	4e-15	89.4
rs:WP_023376403	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	23.32	566	375	19	73	613	74	605	4e-15	89.0
rs:WP_042072215	DNA topoisomerase I [Aeromonas enteropelogenes].	23.60	606	366	23	75	633	82	637	4e-15	89.7
rs:WP_012441352	topoisomerase I [Erwinia tasmaniensis].	22.95	475	308	12	187	633	190	634	4e-15	89.7
rs:WP_019458040	MULTISPECIES: topoisomerase I [Acinetobacter].	23.36	595	369	19	74	629	100	646	4e-15	89.7
rs:WP_013707568	DNA topoisomerase I [Desulfobacca acetoxidans].	23.08	585	378	18	81	630	58	605	4e-15	89.4
rs:WP_002822536	DNA topoisomerase I [Oenococcus oeni].	23.41	581	373	21	83	630	66	607	4e-15	89.4
rs:WP_004916538	DNA topoisomerase I [Acinetobacter junii].	23.14	579	358	19	90	629	117	647	4e-15	89.7
rs:WP_032806012	DNA topoisomerase I [Oenococcus oeni].	23.41	581	373	21	83	630	66	607	4e-15	89.4
rs:WP_008560543	DNA topoisomerase I [Ruegeria sp. R11].	22.18	708	408	29	1	630	1	643	4e-15	89.7
rs:WP_028508714	DNA topoisomerase I [Ruminococcaceae bacterium AB4001].	22.57	678	412	26	2	630	4	617	4e-15	89.4
rs:WP_007399927	DNA topoisomerase I [Gluconacetobacter sp. SXCC-1].	21.66	637	409	24	55	630	28	635	4e-15	89.7
rs:WP_004958844	DNA topoisomerase I [Acinetobacter junii].	23.14	579	358	19	90	629	117	647	4e-15	89.7
rs:WP_011539659	DNA topoisomerase I [Ruegeria sp. TM1040].	22.68	701	413	28	1	630	1	643	4e-15	89.7
rs:WP_041373011	DNA topoisomerase [Methylobacterium radiotolerans].	22.68	604	382	25	44	580	27	612	5e-15	89.4
rs:WP_014634563	DNA topoisomerase I [Streptococcus salivarius].	22.95	562	356	22	103	630	108	626	5e-15	89.4
tr:N1W6Q6_9LEPT	SubName: Full=Putative DNA topoisomerase I {ECO:0000313|EMBL:EMY68927.1};	23.04	473	312	9	87	536	21	464	5e-15	89.0
rs:WP_006922415	DNA topoisomerase I [Desulfovibrio magneticus].	23.85	650	386	30	76	669	53	649	5e-15	89.4
rs:WP_026817248	DNA topoisomerase I [Arenimonas composti].	24.11	477	291	14	103	538	80	526	5e-15	89.7
rs:WP_019570205	DNA topoisomerase I [Thioalkalivibrio sp. ALE11].	23.10	567	350	18	3	534	5	520	5e-15	89.7
rs:WP_042061362	DNA topoisomerase I [Aeromonas allosaccharophila].	23.76	606	365	23	75	633	82	637	5e-15	89.7
rs:WP_013390513	MULTISPECIES: DNA topoisomerase I [Bacillus subtilis group].	23.63	567	373	21	105	641	82	618	5e-15	89.4
rs:WP_023825648	DNA topoisomerase I [Mesorhizobium sp. L103C131B0].	22.68	701	403	26	1	630	1	633	5e-15	89.7
rs:WP_003462075	topoisomerase I [Pseudomonas pseudoalcaligenes].	23.40	483	296	13	186	633	194	637	5e-15	89.7
tr:A0A090SLL0_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL27763.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL27763.1};	27.13	317	192	12	1	291	1	304	5e-15	86.7
rs:WP_027493257	DNA topoisomerase I [Rhodanobacter sp. OR444].	23.47	507	313	13	77	538	54	530	5e-15	89.4
tr:A0A0B7INK9_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.09	538	319	18	3	521	12	484	5e-15	89.7
rs:XP_006797644	PREDICTED: DNA topoisomerase 3-beta-1-like [Neolamprologus brichardi].	22.28	615	379	21	3	564	5	573	5e-15	89.7
rs:WP_032820195	DNA topoisomerase I, partial [Oenococcus oeni].	23.41	581	373	21	83	630	69	610	5e-15	89.4
rs:WP_036138397	DNA topoisomerase I [Luteibacter sp. 9135].	24.32	407	249	11	163	536	142	522	5e-15	89.7
rs:WP_026610181	DNA topoisomerase I [Methylocaldum szegediense].	23.63	567	346	19	3	534	5	519	5e-15	89.4
rs:WP_037127390	DNA topoisomerase I [Rhizobium sp. CF394].	21.61	694	423	25	1	630	1	637	5e-15	89.7
rs:WP_007347925	DNA topoisomerase I [Bartonella rattimassiliensis].	23.78	698	398	29	1	629	1	633	5e-15	89.7
rs:WP_042145160	DNA topoisomerase I [Pseudoalteromonas sp. '520P1 No. 412'].	23.24	624	389	22	51	629	61	639	5e-15	89.7
rs:WP_046742933	DNA topoisomerase I [Kordia sp. MCCC 1A00726].	24.81	673	374	27	3	621	5	599	5e-15	89.4
rs:WP_017400709	topoisomerase I [Acinetobacter radioresistens].	23.70	595	363	20	76	629	104	648	5e-15	89.7
rs:WP_031905008	DNA topoisomerase III, partial [Staphylococcus aureus].	26.10	272	186	5	355	620	7	269	5e-15	87.0
rs:WP_044423340	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	28.65	178	120	3	1	177	1	172	5e-15	84.7
rs:WP_036870289	DNA topoisomerase I [Prevotella histicola].	23.68	608	362	21	3	580	5	540	5e-15	89.4
rs:WP_002691935	DNA topoisomerase I [Beggiatoa alba].	22.29	673	420	25	3	630	5	619	5e-15	89.4
rs:WP_042006265	DNA topoisomerase I [Capnocytophaga canimorsus].	25.09	538	319	18	3	521	5	477	5e-15	89.4
rs:WP_034682714	DNA topoisomerase I [Acinetobacter baumannii].	23.70	595	363	20	76	629	104	648	5e-15	89.7
rs:WP_042744536	DNA topoisomerase I, partial [Oenococcus oeni].	23.41	581	373	21	83	630	66	607	5e-15	89.4
rs:XP_010750977	PREDICTED: DNA topoisomerase 3-beta-1 [Larimichthys crocea].	22.24	616	380	20	3	564	5	575	5e-15	89.0
rs:WP_022149077	DNA topoisomerase [Prevotella sp. CAG:1320].	21.69	627	396	20	3	602	5	563	5e-15	89.4
gp:Z14112_1	DNA topoisomerase I [Bacillus firmus]	28.05	246	162	6	41	272	16	260	5e-15	85.9
rs:WP_004957737	DNA topoisomerase I [Acinetobacter junii].	23.14	579	358	19	90	629	117	647	5e-15	89.7
tr:J6XYG5_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	27.99	293	176	8	132	399	1	283	5e-15	86.3
rs:WP_021939311	DNA topoisomerase [Coprococcus sp. CAG:782].	24.55	660	379	25	3	616	5	591	5e-15	89.4
rs:WP_002817146	DNA topoisomerase I [Oenococcus oeni].	23.41	581	373	21	83	630	66	607	5e-15	89.4
tr:X0ZH22_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_C00245 {ECO:0000313|EMBL:GAG68624.1};	23.54	480	298	14	190	639	1	441	5e-15	88.6
rs:WP_009410590	DNA topoisomerase I [Capnocytophaga sp. oral taxon 324].	24.67	535	325	16	3	521	5	477	5e-15	89.4
tr:A0A0B7I922_9FLAO	RecName: Full=DNA topoisomerase; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.09	538	319	18	3	521	12	484	5e-15	89.4
rs:WP_003043663	DNA topoisomerase I subunit omega [Sphingopyxis sp. MC1].	22.46	668	428	25	1	630	1	616	5e-15	89.4
rs:WP_008983002	topoisomerase I [Alishewanella agri].	22.95	658	385	26	74	673	76	669	5e-15	89.4
rs:WP_018449835	DNA topoisomerase I [Leptotrichia shahii].	24.51	612	372	21	2	587	4	551	5e-15	89.4
rs:WP_032823308	DNA topoisomerase I [Oenococcus oeni].	23.41	581	373	21	83	630	66	607	5e-15	89.0
tr:T1J1V7_STRMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.63	632	377	24	46	619	63	640	5e-15	89.7
rs:WP_024618391	DNA topoisomerase I [Pseudomonas fluorescens].	23.69	477	302	15	186	633	196	639	5e-15	89.4
rs:WP_021696001	DNA topoisomerase I [Brevundimonas abyssalis].	22.54	559	336	18	1	520	1	501	5e-15	89.4
rs:WP_010701167	DNA topoisomerase I [Bartonella bovis].	23.77	690	408	30	1	629	1	633	5e-15	89.4
rs:WP_022735463	DNA topoisomerase I [Candidatus Pelagibacter ubique].	24.03	699	391	31	1	629	1	629	5e-15	89.4
tr:A0A087F896_9PSED	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.40	483	296	13	186	633	194	637	5e-15	89.4
rs:WP_043188271	DNA topoisomerase I [Pseudomonas rhizosphaerae].	23.27	593	382	22	74	633	87	639	5e-15	89.4
rs:WP_021740085	DNA topoisomerase I [Eubacterium ramulus].	23.16	557	363	16	90	616	67	588	5e-15	89.4
rs:WP_041041004	DNA topoisomerase I [Tolypothrix campylonemoides].	24.65	576	330	21	100	618	82	610	5e-15	89.4
rs:WP_015469497	DNA topoisomerase I [Bdellovibrio exovorus].	24.90	498	295	18	77	530	81	543	5e-15	89.4
rs:WP_042658666	DNA topoisomerase I [Aeromonas allosaccharophila].	23.76	606	365	23	75	633	82	637	5e-15	89.4
rs:WP_009429851	DNA topoisomerase I [Oribacterium sp. oral taxon 108].	23.23	663	381	25	3	616	5	588	5e-15	89.0
rs:WP_025306508	reverse gyrase [Thermocrinis ruber].	24.36	624	366	23	3	595	595	1143	5e-15	89.7
rs:WP_010996787	DNA topoisomerase I [Nostoc sp. PCC 7120].	24.66	588	362	19	79	622	59	609	5e-15	89.4
rs:WP_031994669	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	5e-15	89.4
rs:WP_042344952	DNA topoisomerase I [Capnocytophaga canimorsus].	25.09	538	319	18	3	521	5	477	5e-15	89.4
sp:TOP1_FERIS	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	22.39	670	426	19	2	642	39	643	5e-15	89.4
rs:WP_037587770	DNA topoisomerase I [Staphylococcus aureus].	24.17	575	366	19	90	630	67	605	5e-15	89.0
rs:WP_021987910	DNA topoisomerase [Odoribacter sp. CAG:788].	22.89	651	395	23	3	611	5	590	5e-15	89.4
rs:WP_032596664	hypothetical protein, partial [Bacteroides fragilis].	38.89	126	60	3	1	115	1	120	5e-15	83.2
tr:X8IR60_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.21	672	405	26	3	635	28	627	5e-15	89.4
rs:WP_046738240	DNA topoisomerase I [Acinetobacter sp. AG1].	23.53	578	357	18	90	629	117	647	5e-15	89.4
rs:WP_042251448	DNA topoisomerase I [Paracoccus sp. PAMC 22219].	22.13	705	427	25	1	630	1	658	5e-15	89.4
rs:WP_033133268	DNA topoisomerase I [Acinetobacter sp. MN12].	23.53	578	357	18	90	629	117	647	5e-15	89.4
rs:WP_000655391	DNA topoisomerase I [Helicobacter pylori].	24.24	491	324	13	75	536	46	517	5e-15	89.0
rs:WP_004627000	DNA topoisomerase I [[Clostridium] termitidis].	22.17	627	398	20	90	671	67	648	5e-15	89.0
tr:C7H1D5_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEU98145.1};	32.66	199	121	5	479	671	1	192	5e-15	85.5
rs:WP_047243105	DNA topoisomerase I [Chromobacterium subtsugae].	22.91	502	320	15	164	630	143	612	5e-15	89.4
rs:WP_039001476	DNA topoisomerase I [Halocynthiibacter sp. PAMC 20958].	23.99	596	327	21	1	528	1	538	5e-15	89.4
rs:WP_013687041	DNA topoisomerase I [Fluviicola taffensis].	25.28	538	325	21	3	523	5	482	5e-15	89.4
rs:WP_013729133	topoisomerase I [Lactobacillus buchneri].	33.52	182	115	5	3	179	4	184	5e-15	85.1
rs:WP_020032014	hypothetical protein [gamma proteobacterium SCGC AAA300-D14].	22.69	476	303	12	187	629	201	644	5e-15	89.4
rs:WP_042078125	DNA topoisomerase I [Aeromonas sanarellii].	23.93	489	286	18	187	633	193	637	5e-15	89.4
rs:WP_025732923	DNA topoisomerase I [Carnimonas nigrificans].	24.07	594	380	20	72	633	85	639	5e-15	89.4
rs:WP_035253003	DNA topoisomerase I [Actibacterium atlanticum].	22.46	690	430	22	1	643	1	632	5e-15	89.4
rs:WP_006718223	DNA topoisomerase I [Desulfitobacterium metallireducens].	24.74	477	306	15	88	537	62	512	5e-15	89.0
rs:WP_033142381	DNA topoisomerase I [Blautia producta].	23.89	565	350	18	90	616	67	589	5e-15	89.0
rs:WP_008534745	DNA topoisomerase I [Streptococcus sp. C150].	22.95	562	356	22	103	630	108	626	5e-15	89.0
rs:WP_003328956	DNA topoisomerase I [Bacillus atrophaeus].	23.63	567	373	21	105	641	82	618	5e-15	89.0
rs:WP_012789627	DNA topoisomerase I [Chitinophaga pinensis].	24.29	601	365	21	3	580	5	538	5e-15	89.4
rs:WP_008247632	topoisomerase I [gamma proteobacterium BDW918].	23.24	598	383	20	72	633	88	645	5e-15	89.4
rs:WP_037377166	DNA topoisomerase I [Selenomonas ruminantium].	23.51	553	367	18	90	616	98	620	5e-15	89.4
rs:WP_010891446	hypothetical protein [Bacillus anthracis].	32.98	188	117	4	467	647	87	272	5e-15	85.9
rs:WP_034098770	DNA topoisomerase I [Flavobacterium psychrophilum].	24.02	533	331	20	3	521	5	477	5e-15	89.4
rs:WP_029342082	MULTISPECIES: DNA topoisomerase I [Exiguobacterium].	22.69	661	420	24	3	630	5	607	5e-15	89.0
rs:WP_010514841	DNA topoisomerase I [Komagataeibacter oboediens].	21.67	563	365	20	55	571	28	560	6e-15	89.4
rs:WP_034928589	DNA topoisomerase I [Komagataeibacter rhaeticus].	21.66	637	409	24	55	630	28	635	6e-15	89.4
rs:WP_003245261	topoisomerase I [Pseudomonas mendocina].	23.30	485	294	12	186	633	194	637	6e-15	89.4
rs:WP_019910391	DNA topoisomerase I [Paenibacillus sp. HW567].	22.77	584	386	21	88	636	62	615	6e-15	89.0
tr:A0A061NDD9_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	25.06	419	262	16	163	554	9	402	6e-15	88.6
rs:WP_007647546	topoisomerase I [Shewanella sp. HN-41].	23.41	487	288	18	187	631	198	641	6e-15	89.4
tr:D6E501_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.02	562	354	20	90	616	67	590	6e-15	89.0
tr:C3XFJ0_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.47	672	407	24	3	629	55	657	6e-15	89.4
rs:WP_045025600	DNA topoisomerase I [Draconibacterium sp. JN14CK-3].	23.44	640	382	21	3	615	5	563	6e-15	89.4
rs:WP_012165120	DNA topoisomerase I [Acaryochloris marina].	24.30	572	357	19	81	614	61	594	6e-15	89.0
rs:WP_021219539	topoisomerase I [Pseudomonas alcaligenes].	23.21	474	308	13	186	633	195	638	6e-15	89.4
rs:WP_033935563	DNA topoisomerase I [Lactobacillus mucosae].	24.01	579	364	24	88	629	98	637	6e-15	89.0
rs:WP_045243859	DNA topoisomerase I [Paenibacillus polymyxa].	23.32	566	372	20	103	636	80	615	6e-15	89.0
rs:WP_043373106	DNA topoisomerase [Methylobacterium sp. L2-4].	22.68	604	382	25	44	580	27	612	6e-15	89.4
rs:XP_006938802	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Felis catus].	24.88	414	263	13	188	585	187	568	6e-15	89.4
rs:WP_041692327	DNA topoisomerase I, partial [Erwinia billingiae].	22.86	595	384	20	75	633	79	634	6e-15	89.4
tr:C0S9B3_PARBP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.86	643	396	25	3	585	6	608	6e-15	89.0
rs:WP_004802538	DNA topoisomerase I [Acinetobacter sp. CIP 56.2].	23.53	578	357	18	90	629	117	647	6e-15	89.4
tr:A0A061ITR9_TRYRA	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESL05201.1};	22.44	606	402	21	3	577	6	574	6e-15	89.4
rs:WP_009421909	DNA topoisomerase I [Capnocytophaga sp. oral taxon 412].	24.86	535	324	16	3	521	5	477	6e-15	89.4
rs:WP_032811318	DNA topoisomerase I, partial [Oenococcus oeni].	23.41	581	373	21	83	630	66	607	6e-15	89.0
rs:WP_025905317	DNA topoisomerase I [Staphylococcus sciuri].	24.17	575	366	19	90	630	67	605	6e-15	89.0
rs:WP_010788600	DNA topoisomerase I [Bacillus atrophaeus].	23.81	567	372	21	105	641	82	618	6e-15	89.0
rs:WP_025067094	DNA topoisomerase I [Prevotella denticola].	23.28	610	362	21	3	580	5	540	6e-15	89.0
rs:WP_005977801	DNA topoisomerase I [Ruegeria lacuscaerulensis].	23.60	589	339	21	1	534	1	533	6e-15	89.4
tr:J2I0X1_9BACL	SubName: Full=Topoisomerase IA {ECO:0000313|EMBL:EJL42083.1};	34.32	169	100	5	465	627	23	186	6e-15	85.9
rs:WP_023780594	DNA topoisomerase I [Mesorhizobium sp. LNHC221B00].	22.00	700	409	23	1	630	1	633	6e-15	89.4
tr:A0A0D2FLK0_9EURO	SubName: Full=Capronia semiimmersa strain CBS 27337 unplaced genomic scaffold supercont1.4, whole genome shotgun sequence {ECO:0000313|EMBL:KIW67590.1};	23.73	472	291	15	150	584	165	604	6e-15	89.0
rs:XP_002792973	DNA topoisomerase [Paracoccidioides sp. 'lutzii' Pb01].	23.27	649	386	25	3	585	6	608	6e-15	89.0
rs:WP_033069543	DNA topoisomerase I [Thalassospira australica].	22.68	701	420	25	1	639	1	641	6e-15	89.4
rs:WP_029156120	MULTISPECIES: DNA topoisomerase I [unclassified Cloacimonetes].	23.95	689	421	27	3	656	5	625	6e-15	89.0
rs:WP_023805302	DNA topoisomerase I [Mesorhizobium sp. L2C089B000].	22.68	701	403	26	1	630	1	633	6e-15	89.4
tr:A0A0A1SK48_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.25	569	347	20	103	631	81	605	6e-15	89.0
rs:XP_007091146	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Panthera tigris altaica].	24.88	414	263	13	188	585	187	568	6e-15	89.4
rs:WP_005155136	DNA topoisomerase I [Acinetobacter sp. ANC 3929].	23.53	578	357	18	90	629	117	647	6e-15	89.4
rs:XP_005855616	DNA topoisomerase III [Nannochloropsis gaditana CCMP526].	22.61	566	361	21	4	533	1	525	6e-15	89.4
rs:WP_035416420	DNA topoisomerase III, partial [Bacillus sp. MB2021].	30.87	298	157	16	360	646	12	271	6e-15	86.7
rs:WP_039277129	DNA topoisomerase I [Paenibacillus polymyxa].	23.32	566	372	20	103	636	80	615	6e-15	89.0
rs:WP_016194266	DNA topoisomerase I [Arcticibacter svalbardensis].	23.33	540	333	16	3	520	5	485	6e-15	89.0
rs:WP_043994823	DNA topoisomerase I [Moritella sp. PE36].	22.79	588	388	19	77	633	93	645	6e-15	89.4
rs:WP_008148684	hypothetical protein, partial [Parabacteroides johnsonii].	33.14	169	95	4	1	158	1	162	6e-15	84.0
rs:WP_013618934	DNA topoisomerase I [Bacteroides salanitronis].	24.48	625	378	24	3	604	5	558	6e-15	89.0
rs:WP_047258136	DNA topoisomerase I [Chromobacterium subtsugae].	22.91	502	320	15	164	630	143	612	6e-15	89.0
tr:A0A0C7QKE4_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.25	569	347	20	103	631	81	605	6e-15	89.0
rs:WP_007478962	MULTISPECIES: topoisomerase I [Acinetobacter].	23.36	578	358	18	90	629	117	647	6e-15	89.4
rs:WP_004876697	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	23.36	578	358	18	90	629	117	647	6e-15	89.4
rs:WP_015191856	DNA topoisomerase I [Stanieria cyanosphaera].	24.09	577	337	23	3	530	4	528	6e-15	89.4
rs:WP_023655168	DNA topoisomerase I [Erwinia piriflorinigrans].	24.54	485	288	15	187	633	165	609	6e-15	89.0
tr:X1KIM1_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_C00809 {ECO:0000313|EMBL:GAH89974.1}; Flags: Fragment;	22.75	668	413	22	3	624	2	612	6e-15	88.6
tr:L2Q8S0_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELB50338.1};	33.90	177	99	6	3	168	4	173	6e-15	85.1
tr:A0A090S351_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	23.88	469	290	13	197	633	2	435	6e-15	89.0
rs:WP_032807126	topoisomerase I, partial [Oenococcus oeni].	32.46	191	123	5	3	188	4	193	6e-15	84.7
rs:WP_043941141	DNA topoisomerase I [Weissella cibaria].	23.46	665	405	27	3	629	31	629	6e-15	89.0
rs:WP_039944916	DNA topoisomerase I [Lactobacillus mucosae].	24.01	579	364	24	88	629	98	637	6e-15	89.0
rs:XP_012139434	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Megachile rotundata].	22.20	644	404	21	46	634	884	1485	6e-15	89.7
rs:XP_004498561	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Cicer arietinum].	23.37	646	385	32	32	610	258	860	6e-15	89.4
rs:WP_005280639	DNA topoisomerase I [Acinetobacter sp. NIPH 3623].	23.36	578	358	18	90	629	117	647	6e-15	89.0
rs:WP_016164983	DNA topoisomerase I [Acinetobacter sp. CIP 110321].	23.53	578	357	18	90	629	117	647	6e-15	89.0
tr:A6DJX4_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.50	694	405	23	3	646	6	630	6e-15	89.0
rs:WP_006611233	DNA topoisomerase I [Bradyrhizobium sp. ORS 285].	24.09	685	412	28	1	630	1	632	6e-15	89.4
rs:WP_025677610	DNA topoisomerase I [Paenibacillus polymyxa].	23.32	566	372	20	103	636	80	615	6e-15	89.0
rs:WP_046948315	DNA topoisomerase I [Lactobacillus fermentum].	24.18	579	363	26	88	629	83	622	6e-15	89.0
rs:WP_024599386	DNA topoisomerase I [Pseudoalteromonas haloplanktis].	23.27	593	376	20	76	631	91	641	6e-15	89.0
rs:WP_039605753	DNA topoisomerase I [Pseudomonas tuomuerensis].	22.26	656	410	18	74	684	84	684	6e-15	89.0
rs:WP_005192225	DNA topoisomerase I [Acinetobacter sp. ANC 4105].	23.53	578	357	18	90	629	117	647	6e-15	89.0
rs:WP_038560155	DNA topoisomerase I [Terribacillus aidingensis].	23.64	571	362	22	103	635	80	614	6e-15	89.0
rs:WP_037476183	DNA topoisomerase I [Snodgrassella alvi].	22.40	674	415	26	2	630	4	614	6e-15	89.0
tr:A0A0B8V5Z5_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	23.74	476	301	15	187	633	5	447	6e-15	89.0
tr:A0A0C7IC58_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.25	569	347	20	103	631	81	605	7e-15	89.0
rs:WP_036735187	DNA topoisomerase I, partial [Peptococcaceae bacterium SCADC1_2_3].	25.60	457	285	16	89	517	63	492	7e-15	88.2
rs:WP_025394120	DNA topoisomerase I [Rhizobium leguminosarum].	23.13	670	389	28	38	630	16	636	7e-15	89.0
rs:WP_004182436	DNA topoisomerase I [Streptococcus salivarius].	22.95	562	356	22	103	630	108	626	7e-15	89.0
rs:XP_012139435	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Megachile rotundata].	22.20	644	404	21	46	634	856	1457	7e-15	89.4
tr:A0A0C7SWK7_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.25	569	347	20	103	631	81	605	7e-15	89.0
rs:WP_036659208	DNA topoisomerase I [Paenibacillus sp. FSL H8-457].	24.04	570	363	24	103	636	80	615	7e-15	89.0
rs:WP_011849798	DNA topoisomerase [Pyrobaculum calidifontis].	22.27	633	413	21	1	592	1	595	7e-15	88.6
rs:WP_041999769	DNA topoisomerase I [Aeromonas bivalvium].	22.59	602	377	20	75	633	82	637	7e-15	89.0
rs:WP_028405688	DNA topoisomerase I [Bacillus sp. J13].	23.26	589	377	24	88	636	62	615	7e-15	89.0
rs:WP_038183221	DNA topoisomerase I [Xenorhabdus bovienii].	24.12	485	290	17	187	633	188	632	7e-15	89.0
rs:WP_026451379	DNA topoisomerase I [Aequorivita capsosiphonis].	25.85	530	328	17	3	521	5	480	7e-15	89.0
rs:WP_026500741	DNA topoisomerase I [Bartonella grahamii].	23.24	697	403	27	1	629	1	633	7e-15	89.0
rs:WP_016536693	DNA topoisomerase I [Cedecea davisae].	24.23	487	317	16	73	539	74	528	7e-15	89.0
rs:WP_031991904	DNA topoisomerase I [Acinetobacter baumannii].	24.01	479	286	15	187	629	210	646	7e-15	89.0
rs:XP_003459055	PREDICTED: DNA topoisomerase 3-beta-1 isoformX2 [Oreochromis niloticus].	21.64	610	391	19	3	564	5	575	7e-15	89.0
rs:WP_022212330	DNA topoisomerase [Clostridium sp. CAG:265].	23.41	709	394	27	3	630	5	645	7e-15	88.6
rs:WP_004634250	DNA topoisomerase I [Gemella morbillorum].	25.04	567	339	21	103	629	81	601	7e-15	88.6
rs:WP_031823979	DNA topoisomerase III, partial [Staphylococcus aureus].	36.31	157	77	4	469	615	2	145	7e-15	85.5
rs:WP_031954307	DNA topoisomerase I [Acinetobacter baumannii].	23.66	596	366	20	75	629	99	646	7e-15	89.0
tr:A0A0C7RVM9_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.25	569	347	20	103	631	81	605	7e-15	88.6
rs:WP_016479051	DNA topoisomerase I [Capnocytophaga sp. oral taxon 336].	25.33	533	324	17	3	521	5	477	7e-15	89.0
rs:WP_036621536	DNA topoisomerase I [Paenibacillus alvei].	22.77	571	369	20	103	636	80	615	7e-15	88.6
rs:WP_013909851	DNA topoisomerase I [Thermodesulfobacterium geofontis].	27.20	478	284	15	82	536	56	492	7e-15	88.2
rs:WP_035678852	DNA topoisomerase I [Bradyrhizobium liaoningense].	23.03	686	418	24	1	630	1	632	7e-15	89.0
rs:WP_028181330	MULTISPECIES: DNA topoisomerase I [Bradyrhizobium].	23.03	686	418	24	1	630	1	632	7e-15	89.0
rs:WP_018669350	DNA topoisomerase I [Bacteroides gallinarum].	23.76	623	375	23	3	596	5	556	7e-15	89.0
rs:WP_032876161	DNA topoisomerase I [Acinetobacter baumannii].	23.36	578	358	18	90	629	117	647	7e-15	89.0
tr:S9SHB1_PAEAL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.77	571	369	20	103	636	92	627	7e-15	88.6
rs:WP_023783252	DNA topoisomerase I [Mesorhizobium sp. LNHC220B00].	23.16	708	391	28	1	630	1	633	7e-15	89.0
rs:WP_026657198	DNA topoisomerase IA [Acholeplasma palmae].	23.89	565	333	20	103	629	82	587	7e-15	88.6
rs:WP_025167376	DNA topoisomerase I [Pseudomonas taeanensis].	24.49	486	287	22	186	633	195	638	7e-15	89.0
tr:K2NGF1_TRYCR	SubName: Full=DNA topoisomerase III, putative {ECO:0000313|EMBL:EKF38435.1};	23.23	594	390	20	3	564	6	565	7e-15	89.0
tr:K2EQ64_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.01	654	400	24	1	629	1	582	7e-15	88.6
rs:WP_015871044	topoisomerase I [Edwardsiella ictaluri].	23.62	597	377	19	75	633	79	634	7e-15	89.0
rs:WP_024478965	DNA topoisomerase I [Cellulophaga baltica].	25.47	530	329	16	3	521	5	479	7e-15	89.0
rs:WP_040243726	DNA topoisomerase I [Chromohalobacter japonicus].	25.73	482	286	21	186	633	201	644	7e-15	89.0
rs:WP_019678111	DNA topoisomerase I [Ruminococcus flavefaciens].	24.01	558	360	16	90	616	66	590	7e-15	88.6
rs:WP_021944413	DNA topoisomerase [Clostridium sp. CAG:264].	24.82	568	340	20	90	616	106	627	7e-15	88.6
rs:XP_011094466	PREDICTED: uncharacterized protein LOC105174160 isoform X2 [Sesamum indicum].	23.86	612	378	26	64	615	393	976	7e-15	89.4
rs:WP_010373718	DNA topoisomerase I [Weissella cibaria].	23.46	665	405	27	3	629	31	629	7e-15	88.6
rs:WP_034888609	DNA topoisomerase I [Gillisia sp. Hel_I_29].	25.05	531	328	18	3	521	5	477	7e-15	89.0
rs:WP_024090959	DNA topoisomerase I [Leisingera methylohalidivorans].	22.93	593	333	20	1	534	1	528	7e-15	89.0
rs:WP_029447781	MULTISPECIES: DNA topoisomerase I [Cellulophaga].	25.47	530	329	16	3	521	5	479	7e-15	89.0
tr:A0A0C7GJT9_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.25	569	347	20	103	631	81	605	7e-15	88.6
rs:XP_011094464	PREDICTED: uncharacterized protein LOC105174160 isoform X1 [Sesamum indicum].	23.86	612	378	26	64	615	395	978	7e-15	89.0
rs:WP_031560908	DNA topoisomerase I, partial [Acinetobacter baumannii].	24.01	479	286	15	187	629	25	461	7e-15	88.6
rs:WP_034246926	DNA topoisomerase I [Aquimarina sp. 22II-S11-z7].	26.13	444	285	14	94	526	71	482	7e-15	89.0
rs:WP_024716065	DNA topoisomerase I [Bacillus tequilensis].	22.97	566	380	19	105	642	82	619	7e-15	88.6
rs:WP_023679974	DNA topoisomerase I [Mesorhizobium sp. LSJC280B00].	22.86	700	403	25	1	630	1	633	7e-15	89.0
rs:WP_034214990	DNA topoisomerase I [Lachnoanaerobaculum sp. MSX33].	23.17	561	361	15	90	616	67	591	7e-15	88.6
rs:WP_023770068	MULTISPECIES: DNA topoisomerase I [Mesorhizobium].	23.16	708	391	28	1	630	1	633	7e-15	89.0
rs:XP_011671337	PREDICTED: DNA topoisomerase 3-alpha [Strongylocentrotus purpuratus].	24.64	483	296	18	188	634	229	679	7e-15	89.0
rs:WP_014002039	DNA topoisomerase I [Acidithiobacillus caldus].	22.22	585	388	20	85	630	62	618	7e-15	89.0
rs:WP_043708385	DNA topoisomerase I [Weissella cibaria].	23.46	665	405	27	3	629	31	629	7e-15	88.6
rs:WP_014339360	topoisomerase I [Pseudomonas fluorescens].	23.48	477	303	15	186	633	196	639	7e-15	89.0
rs:WP_040278328	DNA topoisomerase I [Psychroserpens damuponensis].	26.45	397	252	12	154	539	128	495	7e-15	89.0
rs:XP_009353313	PREDICTED: DNA topoisomerase 3 isoform X2 [Pyrus x bretschneideri].	23.01	604	382	25	64	610	85	662	7e-15	89.0
tr:H0Y6W0_HUMAN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.28	416	263	13	188	585	7	388	7e-15	88.2
rs:WP_012628662	DNA topoisomerase I [Cyanothece sp. PCC 7425].	23.89	632	370	23	3	577	4	581	8e-15	89.0
rs:WP_045639399	DNA topoisomerase I [Flavobacteriales bacterium BRH_c54].	25.05	539	318	19	3	520	5	478	8e-15	89.0
rs:WP_028289569	DNA topoisomerase I [Olleya sp. VCSA23].	24.86	531	329	19	3	521	5	477	8e-15	89.0
rs:WP_035623890	DNA topoisomerase I, partial [Lachnospiraceae bacterium C6A11].	23.68	663	411	25	55	675	29	638	8e-15	88.6
rs:WP_021444488	topoisomerase I [Pseudomonas sp. EGD-AK9].	23.19	483	297	13	186	633	194	637	8e-15	89.0
rs:WP_018677342	topoisomerase I [Acinetobacter tjernbergiae].	23.36	578	358	18	90	629	117	647	8e-15	89.0
rs:WP_021246507	DNA topoisomerase I [Sphingobium baderi].	21.34	670	430	20	1	629	1	614	8e-15	89.0
rs:WP_040943789	DNA topoisomerase I [Prochloron didemni].	21.85	627	385	21	3	572	4	582	8e-15	89.0
rs:WP_014967754	DNA topoisomerase I [Gottschalkia acidurici].	22.02	654	399	21	3	616	5	587	8e-15	88.6
rs:WP_022230020	DNA topoisomerase [Firmicutes bacterium CAG:41].	23.18	522	335	20	187	678	16	501	8e-15	88.2
rs:WP_022960093	topoisomerase I [Spongiibacter tropicus].	23.64	605	361	21	76	633	94	644	8e-15	89.0
rs:WP_042037482	DNA topoisomerase I [Aeromonas popoffii].	23.43	606	367	22	75	633	82	637	8e-15	89.0
rs:WP_022089219	DNA topoisomerase [Eubacterium sp. CAG:156].	23.34	574	342	19	90	616	67	589	8e-15	88.6
rs:WP_013370667	DNA topoisomerase I [Paenibacillus polymyxa].	23.14	566	373	20	103	636	80	615	8e-15	88.6
tr:F3IVS0_PSEAP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	23.79	475	302	14	187	633	59	501	8e-15	88.6
rs:WP_017639782	topoisomerase I [Pseudomonas sp. 313].	23.79	475	302	15	187	633	195	637	8e-15	89.0
rs:WP_021668948	toprim domain protein, partial [Prevotella disiens].	33.14	172	97	5	4	164	5	169	8e-15	84.0
rs:WP_005218427	DNA topoisomerase I [Acinetobacter sp. ANC 3862].	23.32	579	357	19	90	629	117	647	8e-15	89.0
rs:WP_032870742	DNA topoisomerase I [Acinetobacter baumannii].	23.36	578	358	18	90	629	117	647	8e-15	89.0
rs:WP_004656000	DNA topoisomerase I [Acinetobacter sp. NIPH 809].	23.32	579	357	19	90	629	117	647	8e-15	89.0
rs:WP_014562385	DNA topoisomerase I [Lactobacillus fermentum].	23.36	578	369	23	88	629	85	624	8e-15	88.6
rs:WP_026147909	DNA topoisomerase I [Robiginitomaculum antarcticum].	23.52	591	374	24	90	629	65	628	8e-15	89.0
rs:WP_023720102	DNA topoisomerase I [Mesorhizobium sp. LSHC420B00].	22.29	700	407	26	1	630	1	633	8e-15	89.0
tr:Q1PYZ6_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.27	687	415	27	3	640	8	624	8e-15	88.6
tr:A0A0D2DXX3_9EURO	SubName: Full=Unplaced genomic scaffold supercont1.3, whole genome shotgun sequence {ECO:0000313|EMBL:KIW82651.1};	24.48	482	297	19	150	593	184	636	8e-15	88.6
rs:WP_028135920	DNA topoisomerase I [Bradyrhizobium japonicum].	22.74	686	420	24	1	630	1	632	8e-15	89.0
rs:WP_007560043	DNA topoisomerase I [Bacteroides plebeius].	23.60	534	342	15	3	526	5	482	8e-15	88.6
rs:WP_024590097	MULTISPECIES: DNA topoisomerase I [Pseudoalteromonas].	23.27	593	376	20	76	631	91	641	8e-15	89.0
rs:WP_035639421	hypothetical protein, partial [Bradyrhizobium sp. ORS 375].	24.52	624	379	25	64	630	11	599	8e-15	89.0
rs:WP_044631157	DNA topoisomerase I [Tamlana sedimentorum].	24.71	680	366	28	3	621	5	599	8e-15	88.6
rs:WP_023273414	DNA topoisomerase I [Acinetobacter nectaris].	23.82	487	277	17	187	629	213	649	8e-15	89.0
rs:WP_022346656	DNA topoisomerase [Clostridium sp. CAG:299].	22.91	563	364	18	90	616	67	595	8e-15	88.6
tr:N2BCF8_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.71	678	398	26	3	629	55	657	8e-15	88.6
rs:WP_016780049	topoisomerase I [Pseudomonas fragi].	21.96	592	391	16	74	633	87	639	8e-15	89.0
rs:WP_020037415	hypothetical protein [gamma proteobacterium SCGC AAA168-P09].	23.72	645	416	25	3	616	5	604	8e-15	88.6
rs:WP_013990513	DNA topoisomerase I [Streptococcus salivarius].	22.95	562	356	22	103	630	108	626	8e-15	88.6
rs:WP_020039083	DNA topoisomerase I [Salipiger mucosus].	22.17	600	347	21	1	534	1	546	8e-15	89.0
rs:WP_022118872	DNA topoisomerase [Firmicutes bacterium CAG:56].	25.13	569	338	21	90	616	67	589	8e-15	88.6
rs:WP_003199646	MULTISPECIES: topoisomerase I [Pseudomonas].	23.48	477	303	15	186	633	196	639	8e-15	88.6
rs:WP_024034037	topoisomerase I [Pseudoalteromonas sp. NW 4327].	23.31	622	399	22	49	631	59	641	8e-15	89.0
rs:WP_020466884	DNA topoisomerase I [Singulisphaera acidiphila].	24.44	585	353	19	90	631	63	601	8e-15	88.6
rs:WP_019231241	hypothetical protein [Rickettsiaceae bacterium Os18].	23.26	688	416	22	1	630	1	634	8e-15	88.6
rs:WP_035651805	DNA topoisomerase I [Flavobacterium sp. Fl].	24.11	531	333	18	3	521	5	477	8e-15	88.6
rs:WP_046065291	DNA topoisomerase I [Pseudomonas kilonensis].	23.48	477	303	15	186	633	196	639	8e-15	88.6
rs:WP_029800604	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	35.20	125	81	0	457	581	14	138	8e-15	84.0
rs:WP_025767074	hypothetical protein [Vibrio parahaemolyticus].	23.96	647	349	29	30	560	28	647	8e-15	88.6
rs:WP_034371259	DNA topoisomerase I, partial [Helicobacter sp. MIT 05-5293].	23.62	652	386	24	3	614	4	583	8e-15	88.2
rs:WP_019530187	topoisomerase I [Dasania marina].	23.88	603	372	24	72	633	85	641	9e-15	88.6
rs:WP_019893231	hypothetical protein [Allobaculum stercoricanis].	22.72	647	400	21	3	614	5	586	9e-15	88.6
rs:WP_034281770	DNA topoisomerase I [Bacillus safensis].	23.39	560	374	21	105	636	82	614	9e-15	88.6
rs:WP_023667567	DNA topoisomerase I [Mesorhizobium sp. LSJC285A00].	22.54	701	404	26	1	630	1	633	9e-15	88.6
rs:WP_013292006	DNA topoisomerase I [Gallionella capsiferriformans].	25.13	581	339	25	100	629	77	612	9e-15	88.6
rs:WP_027124448	DNA topoisomerase I [Gelidibacter mesophilus].	23.74	535	330	17	3	521	5	477	9e-15	88.6
rs:WP_007823946	DNA topoisomerase I [Rhizobium sp. CF142].	23.40	671	387	30	38	630	16	637	9e-15	88.6
rs:WP_011678373	DNA topoisomerase I [Lactobacillus delbrueckii].	22.50	551	370	15	90	616	98	615	9e-15	88.6
rs:WP_003618692	DNA topoisomerase I [Lactobacillus delbrueckii].	22.50	551	370	15	90	616	100	617	9e-15	88.6
rs:WP_035335751	DNA topoisomerase I [Dokdonia sp. PRO95].	25.61	535	320	19	3	521	5	477	9e-15	88.6
rs:WP_026742481	DNA topoisomerase I [Lonsdalea quercina].	21.33	633	420	18	77	673	83	673	9e-15	88.6
rs:WP_040484655	DNA topoisomerase I [Lyngbya aestuarii].	24.88	615	356	25	3	564	4	565	9e-15	88.6
rs:WP_041413613	DNA topoisomerase I [Shewanella frigidimarina].	22.22	648	422	23	72	680	83	687	9e-15	88.6
rs:WP_004774272	DNA topoisomerase I [Acinetobacter sp. NIPH 758].	23.36	578	358	18	90	629	117	647	9e-15	88.6
rs:WP_035517327	DNA topoisomerase I [Pseudohaliea rubra].	22.94	606	369	21	74	633	93	646	9e-15	88.6
rs:WP_032999419	DNA topoisomerase I, partial [Mesorhizobium sp. LNJC405B00].	22.54	701	404	26	1	630	1	633	9e-15	88.6
rs:WP_034328503	MULTISPECIES: DNA topoisomerase I [Helicobacter].	24.75	501	328	14	103	578	78	554	9e-15	88.2
rs:WP_016171692	DNA topoisomerase 1 [Enterococcus dispar].	24.96	569	356	22	103	635	81	614	9e-15	88.6
tr:E6LFJ8_9ENTE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.10	585	374	24	88	635	70	621	9e-15	88.6
rs:WP_012285560	DNA topoisomerase I [Caulobacter sp. K31].	21.35	698	410	24	1	630	1	627	9e-15	88.6
rs:WP_031804255	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	23.52	472	295	14	74	520	85	515	9e-15	87.8
rs:XP_003702899	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Megachile rotundata].	22.20	644	404	21	46	634	536	1137	9e-15	89.0
rs:XP_011651110	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Cucumis sativus].	21.95	524	355	15	90	589	40	533	9e-15	88.6
tr:G9QZP6_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHM92695.1};	35.60	191	114	4	375	561	6	191	9e-15	84.3
tr:H0SCA3_9BRAD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.50	604	369	23	84	630	10	583	9e-15	88.6
rs:WP_006518469	DNA topoisomerase I [Leptolyngbya sp. PCC 7375].	25.06	411	249	9	187	560	173	561	9e-15	88.6
rs:WP_021584229	DNA topoisomerase I [Prevotella pleuritidis].	24.75	594	365	20	3	578	5	534	9e-15	88.6
rs:WP_043042019	DNA topoisomerase I [Pseudomonas fluorescens].	23.48	477	303	15	186	633	196	639	9e-15	88.6
tr:A0A077WA56_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.63	579	357	21	5	537	3	536	9e-15	87.8
rs:WP_020303003	DNA topoisomerase I [Pseudomonas sp. CF150].	22.42	562	380	12	77	614	62	591	9e-15	88.2
rs:WP_022168066	DNA topoisomerase [Clostridium sp. CAG:221].	24.31	654	383	24	3	616	5	586	9e-15	88.2
tr:A0A0B0KP49_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.36	578	358	18	90	629	117	647	9e-15	88.6
rs:WP_040366499	DNA topoisomerase I [Enterococcus italicus].	24.10	585	374	24	88	635	63	614	9e-15	88.2
rs:WP_016587519	topoisomerase I, partial [Yersinia pestis].	22.84	648	380	22	83	673	2	586	9e-15	88.6
rs:WP_006341833	DNA topoisomerase I [Parachlamydia acanthamoebae].	22.53	577	351	18	3	537	5	527	9e-15	88.6
rs:WP_027050377	DNA topoisomerase I [Mesorhizobium sp. URHB0007].	22.54	701	404	26	1	630	1	633	9e-15	88.6
rs:WP_036381104	DNA topoisomerase I [Mogibacterium timidum].	23.07	672	406	26	3	635	1	600	9e-15	88.2
rs:WP_021910210	DNA topoisomerase I [Prevotella sp. CAG:755].	23.99	546	318	20	3	520	5	481	9e-15	88.6
rs:WP_034861517	DNA topoisomerase I [Enterobacteriaceae bacterium B14].	24.17	600	370	22	74	633	80	634	9e-15	88.6
rs:WP_045688840	DNA topoisomerase I [Hymenobacter sp. AT01-02].	24.79	468	307	11	74	526	51	488	9e-15	88.6
rs:WP_033115350	DNA topoisomerase I [Aeromonas sp. AE122].	23.76	606	365	23	75	633	82	637	9e-15	88.6
rs:WP_031374553	DNA topoisomerase I [Pantoea sp. 3.5.1].	23.22	478	303	16	187	633	190	634	9e-15	88.6
tr:X5Y3R3_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.54	701	404	26	1	630	1	633	9e-15	88.6
rs:WP_021236566	MULTISPECIES: DNA topoisomerase I [Sphingomonadaceae].	21.00	681	431	21	1	629	1	626	9e-15	88.6
rs:WP_043138282	DNA topoisomerase I [Ponticoccus sp. UMTAT08].	22.77	584	352	17	1	534	1	535	9e-15	88.6
rs:WP_026837499	DNA topoisomerase I [Gillisia sp. JM1].	27.53	465	282	20	74	521	51	477	9e-15	88.6
rs:WP_021778244	DNA topoisomerase I [Dokdonia sp. MED134].	25.46	538	317	20	3	521	5	477	1e-14	88.6
rs:WP_003613142	DNA topoisomerase I [Lactobacillus delbrueckii].	22.50	551	370	15	90	616	97	614	1e-14	88.2
rs:WP_014565034	DNA topoisomerase I [Lactobacillus delbrueckii].	22.32	551	371	15	90	616	100	617	1e-14	88.2
rs:WP_038243097	DNA topoisomerase I [Xenorhabdus bovienii].	24.12	485	290	17	187	633	188	632	1e-14	88.6
rs:WP_012742655	DNA topoisomerase I [Eubacterium rectale].	24.02	562	354	20	90	616	67	590	1e-14	88.2
rs:WP_015856428	DNA topoisomerase I [Bartonella grahamii].	23.10	697	404	27	1	629	1	633	1e-14	88.6
rs:WP_002386831	DNA topoisomerase I, partial [Enterococcus faecalis].	24.95	517	322	20	103	590	81	560	1e-14	87.8
rs:WP_005226653	DNA topoisomerase I [Acinetobacter sp. NIPH 1847].	23.36	578	358	18	90	629	117	647	1e-14	88.6
tr:A6FH32_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.79	588	388	19	77	633	86	638	1e-14	88.6
rs:WP_013040040	DNA topoisomerase I [Sphingobium japonicum].	21.69	687	419	25	1	629	1	626	1e-14	88.6
rs:WP_011762147	DNA topoisomerase [Pyrobaculum islandicum].	21.33	633	419	19	1	599	1	588	1e-14	88.2
tr:A0A0D6NPJ8_9PROT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAN68032.1};	22.71	643	394	25	55	630	28	634	1e-14	88.6
rs:WP_002681710	DNA topoisomerase I [Capnocytophaga sputigena].	25.79	535	319	20	3	521	5	477	1e-14	88.6
tr:K1UET1_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC78504.1}; Flags: Fragment;	26.67	285	186	10	196	473	1	269	1e-14	85.1
rs:WP_006857504	DNA topoisomerase I [Roseburia intestinalis].	24.38	562	351	21	90	616	67	589	1e-14	88.2
rs:XP_005261870	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Homo sapiens].	24.28	416	263	13	188	585	76	457	1e-14	88.2
rs:WP_026739446	DNA topoisomerase I [Lonsdalea quercina].	21.17	633	421	18	77	673	83	673	1e-14	88.6
rs:WP_024603974	DNA topoisomerase I [Pseudoalteromonas haloplanktis].	23.20	625	396	23	49	631	59	641	1e-14	88.6
tr:A7VIM6_9CLOT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.82	568	340	20	90	616	98	619	1e-14	88.2
rs:WP_029238789	DNA topoisomerase I, partial [Streptococcus sobrinus].	23.73	510	325	18	83	564	87	560	1e-14	87.8
rs:WP_043342545	DNA topoisomerase [Methylobacterium sp. EUR3 AL-11].	22.68	604	382	25	44	580	27	612	1e-14	88.2
rs:WP_012259747	MULTISPECIES: DNA topoisomerase I [Chloroflexus].	22.91	633	376	20	83	645	58	648	1e-14	88.2
rs:WP_036891834	hypothetical protein, partial [Prevotella corporis].	26.26	278	188	6	309	578	1	269	1e-14	85.5
rs:WP_024592543	DNA topoisomerase I [Pseudoalteromonas haloplanktis].	23.27	593	376	20	76	631	91	641	1e-14	88.6
rs:WP_007582594	topoisomerase I [Pseudoalteromonas sp. BSi20429].	23.27	593	376	20	76	631	91	641	1e-14	88.6
rs:WP_025908998	DNA topoisomerase I [Bacillus flexus].	23.39	560	372	22	105	635	82	613	1e-14	88.2
rs:WP_022040214	DNA topoisomerase [Bacteroides sp. CAG:702].	22.79	623	381	19	3	604	6	549	1e-14	88.2
tr:K1SSS7_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central domain protein {ECO:0000313|EMBL:EKC60568.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EKC60568.1}; Flags: Fragment;	28.77	219	145	4	368	581	1	213	1e-14	84.3
rs:WP_011009064	DNA topoisomerase [Pyrobaculum aerophilum].	22.94	619	398	20	1	581	1	578	1e-14	87.8
rs:WP_024334496	DNA topoisomerase I [Desulfotignum balticum].	25.00	592	355	23	82	629	59	605	1e-14	88.2
rs:WP_000210271	MULTISPECIES: DNA topoisomerase I [Gammaproteobacteria].	22.59	571	367	16	90	631	65	589	1e-14	88.2
rs:XP_009436166	PREDICTED: DNA topoisomerase 3-beta-1 isoform X4 [Pan troglodytes].	24.28	416	263	13	188	585	76	457	1e-14	88.2
rs:WP_020527395	hypothetical protein [Flexithrix dorotheae].	24.53	534	328	15	3	520	5	479	1e-14	88.2
rs:WP_023822968	DNA topoisomerase I [Mesorhizobium sp. L103C565B0].	22.54	701	404	26	1	630	1	633	1e-14	88.6
rs:WP_008166223	topoisomerase I [Pseudoalteromonas sp. BSi20652].	23.27	593	376	20	76	631	91	641	1e-14	88.6
rs:WP_027182567	DNA topoisomerase I [Desulfovibrio alaskensis].	22.56	656	394	24	77	672	54	655	1e-14	88.2
rs:WP_023828664	DNA topoisomerase I [Mesorhizobium sp. L103C120A0].	22.54	701	404	26	1	630	1	633	1e-14	88.6
rs:WP_003136185	DNA topoisomerase I [Lactococcus garvieae].	24.46	560	351	22	103	630	109	628	1e-14	88.2
rs:WP_034556294	DNA topoisomerase I [Capnocytophaga ochracea].	24.67	535	325	16	3	521	5	477	1e-14	88.2
rs:WP_013291693	DNA topoisomerase I [Clostridium cellulovorans].	24.26	573	355	19	83	616	60	592	1e-14	88.2
rs:WP_020588848	DNA topoisomerase I [Desulfobacter curvatus].	23.97	559	369	18	82	614	59	587	1e-14	88.2
tr:E8KVD5_STRVE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.23	508	320	20	154	630	37	505	1e-14	87.8
rs:WP_008089323	DNA topoisomerase I [Streptococcus ictaluri].	23.20	582	369	23	83	629	84	622	1e-14	88.2
rs:WP_018644533	DNA topoisomerase I [Bradyrhizobium japonicum].	23.15	704	429	25	1	647	1	649	1e-14	88.6
rs:WP_020031242	hypothetical protein [gamma proteobacterium SCGC AAA168-I18].	23.91	640	413	23	3	612	5	600	1e-14	88.6
rs:WP_044946190	DNA topoisomerase I [Clostridium sp. L2-50].	24.82	568	340	20	90	616	67	588	1e-14	88.2
tr:F6SDD7_MOUSE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.12	414	262	15	188	585	7	388	1e-14	87.8
rs:WP_008493015	DNA topoisomerase I [Acidocella sp. MX-AZ02].	25.00	516	326	17	55	534	28	518	1e-14	88.6
rs:WP_018696524	DNA topoisomerase I [Alistipes onderdonkii].	23.25	542	338	18	3	526	5	486	1e-14	88.2
rs:WP_022657618	DNA topoisomerase I [Desulfovibrio desulfuricans].	23.79	597	366	23	76	630	53	602	1e-14	88.2
rs:XP_003239054	DNA topoisomerase III [Trichophyton rubrum CBS 118892].	23.58	615	378	23	3	560	6	585	1e-14	87.8
rs:WP_033618822	DNA topoisomerase I [Helicobacter pylori].	24.74	485	329	15	75	536	46	517	1e-14	88.2
rs:WP_009133961	DNA topoisomerase I [Alistipes indistinctus].	23.63	457	309	10	76	520	53	481	1e-14	88.2
rs:WP_023734453	DNA topoisomerase I [Mesorhizobium sp. LNJC403B00].	22.54	701	404	26	1	630	1	633	1e-14	88.2
rs:WP_023821402	DNA topoisomerase I [Mesorhizobium sp. L2C054A000].	22.54	701	404	26	1	630	1	633	1e-14	88.2
rs:WP_044141928	DNA topoisomerase I [Bacillus pumilus].	23.98	563	367	22	105	636	82	614	1e-14	88.2
rs:WP_005255320	DNA topoisomerase I [Acinetobacter sp. NIPH 2168].	23.36	578	358	18	90	629	117	647	1e-14	88.2
tr:Q080J2_SHEFN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.22	648	422	23	72	680	99	703	1e-14	88.2
tr:E4MS88_CAPOC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.14	533	325	17	3	521	25	497	1e-14	88.2
rs:WP_002950606	DNA topoisomerase I [Streptococcus thermophilus].	22.68	560	360	21	103	630	108	626	1e-14	88.2
rs:WP_014828436	DNA topoisomerase I [Desulfosporosinus acidiphilus].	23.01	565	357	20	90	616	67	591	1e-14	88.2
rs:WP_033630456	DNA topoisomerase, partial [Enterococcus faecium].	28.77	212	135	6	471	667	1	211	1e-14	84.3
rs:WP_016182471	DNA topoisomerase 1 [Enterococcus columbae].	24.19	587	371	27	88	635	63	614	1e-14	88.2
rs:WP_003341403	DNA topoisomerase I [Brevibacillus laterosporus].	23.27	563	375	21	103	636	80	614	1e-14	88.2
rs:WP_014621523	DNA topoisomerase I [Streptococcus thermophilus].	22.72	559	361	21	103	630	106	624	1e-14	88.2
rs:WP_015560448	DNA topoisomerase I [Roseburia intestinalis CAG:13].	24.38	562	351	21	90	616	67	589	1e-14	88.2
rs:WP_033742946	DNA topoisomerase I, partial [Helicobacter pylori].	24.74	485	329	15	75	536	3	474	1e-14	87.8
rs:WP_004932739	DNA topoisomerase I [Acinetobacter soli].	23.08	481	288	15	187	629	213	649	1e-14	88.2
rs:WP_024424184	MULTISPECIES: DNA topoisomerase I [Bacillus].	23.80	563	368	22	105	636	82	614	1e-14	88.2
rs:WP_029057500	DNA topoisomerase I [Stappia stellulata].	21.50	665	413	20	1	612	1	609	1e-14	88.2
rs:WP_023741453	DNA topoisomerase I [Mesorhizobium sp. LNJC395A00].	22.54	701	404	26	1	630	1	633	1e-14	88.2
rs:WP_039299944	DNA topoisomerase I [Pectobacterium betavasculorum].	24.33	600	369	23	74	633	81	635	1e-14	88.2
tr:A0A0D9VPW6_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:LPERR03G04240.2};	22.58	651	378	28	3	585	12	604	1e-14	88.2
tr:I9VSY5_BACFG	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EIY99036.1};	37.93	116	56	4	1	109	1	107	1e-14	82.0
rs:WP_007128765	DNA topoisomerase I [Paenibacillus lactis].	23.26	589	377	24	88	636	62	615	1e-14	88.2
rs:WP_027454770	DNA topoisomerase I [Prevotella brevis].	22.49	547	343	16	3	526	5	493	1e-14	88.2
rs:WP_035210349	hypothetical protein, partial [Acidithiobacillus thiooxidans].	24.20	595	365	24	90	650	65	607	1e-14	87.8
rs:WP_023794037	DNA topoisomerase [Candidatus Saccharibacteria bacterium RAAC3_TM7_1].	24.01	583	369	19	74	612	55	607	1e-14	88.2
rs:WP_023512787	DNA topoisomerase 1 [Shinella sp. DD12].	23.39	667	391	27	38	630	16	636	1e-14	88.2
rs:WP_029508697	DNA topoisomerase I [Leuconostoc fallax].	22.67	569	378	17	90	629	51	586	1e-14	87.8
rs:WP_045223170	DNA topoisomerase I, partial [Desulfonatronum thioautotrophicum].	22.42	660	404	29	76	679	53	660	1e-14	88.2
rs:WP_027253391	DNA topoisomerase I [Photobacterium halotolerans].	23.13	588	386	16	76	633	88	639	1e-14	88.2
rs:WP_001725981	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	24.39	488	315	17	73	539	74	528	1e-14	87.4
rs:WP_023725728	MULTISPECIES: DNA topoisomerase I [Mesorhizobium].	22.54	701	404	26	1	630	1	633	1e-14	88.2
rs:WP_021980332	DNA topoisomerase [Paraprevotella clara CAG:116].	23.67	600	366	21	3	580	5	534	1e-14	88.2
rs:WP_043532255	DNA topoisomerase I [Halomonas xinjiangensis].	25.10	486	287	22	186	633	201	647	1e-14	88.2
rs:WP_021127832	DNA topoisomerase I [[Clostridium] sordellii].	24.25	569	347	20	103	631	81	605	1e-14	87.8
rs:WP_007137737	DNA topoisomerase I [Flavobacterium frigoris].	25.05	535	323	20	3	521	5	477	1e-14	88.2
tr:R0U479_NEIME	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.96	561	339	20	3	533	5	513	1e-14	87.4
rs:WP_011153307	hypothetical protein [Nanoarchaeum equitans].	23.00	526	320	15	81	584	142	604	1e-14	87.8
rs:WP_021485677	DNA topoisomerase III [Vibrio parahaemolyticus].	22.29	655	396	20	1	554	1	643	1e-14	88.2
rs:WP_008023233	DNA topoisomerase I [Bacteroides xylanisolvens].	23.26	619	383	21	3	596	5	556	1e-14	88.2
rs:WP_046210735	DNA topoisomerase I [Nautella sp. ECSMB14104].	21.33	708	414	27	1	630	1	643	1e-14	88.2
rs:WP_022035402	GTP-sensing transcriptional pleiotropic repressor CodY [Roseburia sp. CAG:50].	23.41	457	294	13	187	616	17	444	1e-14	87.4
rs:WP_025095361	DNA topoisomerase I [Acinetobacter soli].	23.08	481	288	15	187	629	213	649	1e-14	88.2
rs:WP_006949726	DNA topoisomerase I [Prevotella marshii].	24.50	596	363	22	3	578	5	533	1e-14	88.2
rs:WP_034781453	hypothetical protein, partial [Bacteroides graminisolvens].	23.22	603	368	20	3	581	5	536	1e-14	88.2
rs:XP_010760449	hypothetical protein PADG_04954 [Paracoccidioides brasiliensis Pb18].	22.71	643	397	25	3	585	6	608	1e-14	87.8
rs:WP_010529083	topoisomerase [Lentibacillus jeotgali].	35.34	116	62	3	4	111	5	115	1e-14	82.0
rs:WP_036327146	DNA topoisomerase I [Mollicutes bacterium HR2].	24.11	560	344	17	103	629	83	594	1e-14	87.8
rs:WP_046397491	DNA topoisomerase I [Photorhabdus luminescens].	22.70	652	394	24	75	673	79	673	1e-14	88.2
rs:WP_038294596	DNA topoisomerase I, partial [alpha proteobacterium SCGC AAA027-C06].	23.17	643	381	26	1	597	1	576	1e-14	88.2
rs:WP_011543972	DNA topoisomerase I [Lactobacillus delbrueckii].	22.50	551	370	15	90	616	100	617	1e-14	87.8
rs:WP_010278379	DNA topoisomerase I [Leuconostoc pseudomesenteroides].	22.72	581	363	19	90	629	60	595	1e-14	87.8
rs:WP_046347030	DNA topoisomerase I [Sphingomonas changbaiensis].	22.50	591	377	16	1	566	1	535	1e-14	88.2
rs:WP_005675246	DNA topoisomerase I [Bacteroides caccae].	23.42	619	382	20	3	596	5	556	1e-14	88.2
rs:WP_026773797	DNA topoisomerase I [Sediminibacterium sp. OR43].	25.97	543	321	21	3	525	5	486	1e-14	88.2
rs:WP_036805757	DNA topoisomerase I [Photorhabdus luminescens].	22.70	652	394	24	75	673	79	673	1e-14	88.2
rs:WP_040463505	DNA topoisomerase I [Helicobacter bilis].	22.74	620	393	22	55	629	24	602	1e-14	87.8
rs:WP_015205082	DNA topoisomerase I [Crinalium epipsammum].	23.95	618	350	21	3	560	4	561	1e-14	88.2
tr:A0A059XXD1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.21	672	414	29	3	631	55	667	1e-14	88.2
tr:A0A069D168_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.22	603	368	20	3	581	5	536	1e-14	88.2
rs:XP_011780170	DNA topoisomerase III, putative [Trypanosoma brucei gambiense DAL972].	22.48	605	385	23	3	566	6	567	1e-14	88.2
rs:WP_042867454	DNA topoisomerase I [Aeromonas piscicola].	23.43	606	367	22	75	633	82	637	1e-14	88.2
rs:WP_029685549	DNA topoisomerase I [Tatumella saanichensis].	21.99	473	315	10	187	633	190	634	1e-14	88.2
rs:WP_034646182	DNA topoisomerase I [Cellulophaga geojensis].	24.72	534	327	17	3	521	5	478	1e-14	88.2
rs:WP_032134845	DNA topoisomerase I [Alistipes sp. AL-1].	23.25	542	338	18	3	526	5	486	1e-14	87.8
rs:WP_028576602	DNA topoisomerase I [Desulfomicrobium escambiense].	24.65	568	353	20	76	610	53	578	1e-14	87.8
rs:WP_020515364	DNA topoisomerase I [Actinoplanes globisporus].	23.74	712	394	29	2	642	9	642	1e-14	88.2
rs:WP_026821992	DNA topoisomerase I [Arsenophonus nasoniae].	24.59	488	284	17	187	633	189	633	1e-14	88.2
rs:WP_013445935	DNA topoisomerase I [Paludibacter propionicigenes].	23.70	616	377	22	3	593	5	552	1e-14	88.2
rs:WP_002333472	hypothetical protein, partial [Enterococcus faecium].	30.57	265	146	10	154	391	13	266	1e-14	85.1
rs:WP_023738966	MULTISPECIES: DNA topoisomerase I [Mesorhizobium].	22.54	701	404	26	1	630	1	633	1e-14	88.2
tr:M1ZR26_CLOBO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	34.16	161	83	5	252	399	15	165	1e-14	83.2
rs:WP_044147101	DNA topoisomerase, partial [Enterococcus faecium].	32.67	150	96	4	3	148	5	153	1e-14	82.8
rs:WP_028899889	DNA topoisomerase I [Prevotella sp. HJM029].	23.49	596	373	21	3	580	5	535	1e-14	87.8
rs:WP_026791387	DNA topoisomerase I [Pleomorphomonas oryzae].	22.50	689	419	27	1	630	1	633	1e-14	88.2
tr:U2JGA9_LACPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.22	230	150	5	299	516	1	220	1e-14	84.3
rs:XP_012363345	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-beta-1 [Nomascus leucogenys].	22.13	619	391	22	3	585	5	568	1e-14	88.2
rs:WP_019641165	DNA topoisomerase I [Thioalkalivibrio sp. ALSr1].	23.55	569	345	19	3	534	5	520	1e-14	88.2
tr:G9WHS7_9LACT	SubName: Full=TrsI(TraI) family conjugation protein {ECO:0000313|EMBL:EHN58651.1};	28.95	152	106	1	432	581	34	185	1e-14	85.1
rs:WP_013905219	endonuclease [Pyrococcus yayanosii].	26.67	360	214	12	307	640	782	1117	1e-14	88.2
rs:WP_013905219	endonuclease [Pyrococcus yayanosii].	26.75	329	211	11	1	310	1	318	3e-13	84.0
rs:WP_013272516	DNA topoisomerase I [[Clostridium] saccharolyticum].	24.56	562	352	18	90	616	67	591	1e-14	87.8
rs:WP_001734569	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	24.39	488	315	17	73	539	74	528	1e-14	87.4
rs:WP_009217720	DNA topoisomerase I [Bacteroidetes oral taxon 274].	24.15	468	309	15	71	523	61	497	1e-14	88.2
rs:WP_000366820	hypothetical protein, partial [Acinetobacter baumannii].	30.60	183	115	4	1	179	1	175	1e-14	83.6
tr:E1NPC4_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	25.25	396	238	15	258	629	22	383	1e-14	87.0
tr:T0P3I5_PHOTE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQB98911.1};	34.31	137	83	1	475	611	1	130	1e-14	83.6
rs:WP_007367631	DNA topoisomerase I [Prevotella multiformis].	23.93	610	358	22	3	580	5	540	1e-14	87.8
rs:WP_033639842	DNA topoisomerase I, partial [Helicobacter pylori].	24.07	486	331	14	75	536	46	517	1e-14	87.4
rs:WP_015317636	DNA topoisomerase I [Mesorhizobium australicum].	22.84	705	397	27	1	630	1	633	1e-14	88.2
rs:WP_023710622	MULTISPECIES: DNA topoisomerase I [Mesorhizobium].	22.54	701	404	26	1	630	1	633	1e-14	88.2
rs:WP_016669102	DNA topoisomerase I [Propionibacterium sp. oral taxon 192].	23.91	640	359	22	2	571	7	588	1e-14	88.2
rs:WP_017972098	DNA topoisomerase I [alpha proteobacterium SCGC AAA280-B11].	22.95	645	380	25	1	597	1	576	1e-14	87.8
rs:WP_019968915	DNA topoisomerase I [Prevotella maculosa].	23.28	597	373	19	3	580	5	535	1e-14	87.8
rs:WP_013631854	DNA topoisomerase I [Pedobacter saltans].	22.67	600	370	20	3	578	5	534	1e-14	87.8
rs:WP_026898152	DNA topoisomerase I [Pedobacter oryzae].	24.79	468	306	13	76	525	53	492	1e-14	87.8
tr:A0A0E2RVE6_STRTR	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EWM61844.1};	22.72	559	361	21	103	630	106	624	1e-14	87.8
rs:WP_011681086	DNA topoisomerase I [Streptococcus thermophilus].	22.72	559	361	21	103	630	108	626	1e-14	87.8
rs:WP_023714241	DNA topoisomerase I [Mesorhizobium sp. LSHC422A00].	22.54	701	404	26	1	630	1	633	1e-14	88.2
rs:WP_013620341	DNA topoisomerase I [Cellulophaga lytica].	24.72	534	327	17	3	521	5	478	1e-14	87.8
rs:WP_019021654	DNA topoisomerase I [Thioalkalivibrio sp. ALE23].	22.93	567	351	18	3	534	5	520	1e-14	88.2
rs:WP_035023093	DNA topoisomerase I [Carnobacterium sp. WN1374].	22.98	583	376	23	90	635	68	614	1e-14	87.8
rs:WP_037330088	hypothetical protein, partial [Anaerovibrio lipolyticus].	24.49	486	306	18	163	616	178	634	1e-14	87.8
rs:WP_013502024	DNA topoisomerase I [Rhodopseudomonas palustris].	23.48	690	411	29	1	630	1	633	1e-14	88.2
tr:A0A009N8A3_ACIBA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.53	595	364	20	76	629	79	623	1e-14	87.8
rs:WP_034165152	DNA topoisomerase I [Edwardsiella tarda].	24.26	606	362	23	75	633	79	634	1e-14	87.8
rs:WP_040418491	DNA topoisomerase I [Desulfonatronospira thiodismutans].	23.58	670	418	26	3	639	5	613	1e-14	87.8
rs:WP_042401696	hypothetical protein [Geomicrobium sp. JCM 19037].	35.53	152	87	4	248	391	38	186	1e-14	83.6
rs:WP_006934918	DNA topoisomerase I [Labrenzia aggregata].	24.70	579	336	23	1	534	1	524	1e-14	87.8
rs:WP_020820769	MULTISPECIES: DNA topoisomerase I [Sphingobium].	21.57	686	421	24	1	629	1	626	1e-14	87.8
rs:WP_038504905	DNA topoisomerase I [Cellulophaga lytica].	24.72	534	327	17	3	521	5	478	1e-14	87.8
rs:WP_040914528	hypothetical protein, partial [Lentisphaera araneosa].	25.04	575	347	18	55	579	30	570	1e-14	87.4
tr:A0A0C7RRP1_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.25	569	347	20	103	631	81	605	1e-14	87.8
rs:WP_010262215	DNA topoisomerase I [Alistipes timonensis].	24.84	467	298	16	77	525	54	485	1e-14	87.8
rs:WP_033756362	DNA topoisomerase I [Helicobacter pylori].	24.74	485	329	15	75	536	46	517	1e-14	87.8
rs:WP_044203746	DNA topoisomerase I [Chlamydia psittaci].	23.06	707	383	25	77	670	29	687	1e-14	87.8
rs:WP_004668544	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	22.93	580	358	19	90	629	117	647	1e-14	87.8
rs:WP_027130929	DNA topoisomerase I [Gemella cuniculi].	24.69	567	342	19	103	629	81	602	1e-14	87.8
rs:XP_010093883	DNA topoisomerase 3-beta-1 [Morus notabilis].	23.11	424	280	12	224	631	19	412	2e-14	87.4
rs:WP_034525921	DNA topoisomerase I [Bacteroides uniformis].	23.43	542	328	19	3	520	5	483	2e-14	87.8
rs:WP_012459087	DNA topoisomerase I [Sulfurihydrogenibium sp. YO3AOP1].	30.58	327	179	12	2	314	5	297	2e-14	87.8
rs:WP_001722109	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	24.39	488	315	17	73	539	74	528	2e-14	87.0
rs:WP_021689324	DNA topoisomerase I [Novosphingobium tardaugens].	22.06	671	425	21	1	629	1	615	2e-14	87.8
rs:WP_027305949	DNA topoisomerase I [Campylobacter cuniculorum].	23.32	506	340	13	93	576	69	548	2e-14	87.4
rs:WP_023695425	MULTISPECIES: DNA topoisomerase I [Mesorhizobium].	22.54	701	404	26	1	630	1	633	2e-14	87.8
rs:WP_043074761	DNA topoisomerase [Methylobacterium radiotolerans].	22.52	604	383	25	44	580	27	612	2e-14	87.8
rs:WP_003615350	DNA topoisomerase I [Lactobacillus delbrueckii].	22.50	551	370	15	90	616	97	614	2e-14	87.8
rs:WP_012083020	DNA topoisomerase I [Nitratiruptor sp. SB155-2].	23.74	636	401	21	3	614	5	580	2e-14	87.8
rs:WP_006849198	DNA topoisomerase I [Prevotella copri].	23.76	623	386	23	3	602	5	561	2e-14	87.8
rs:WP_016272395	DNA topoisomerase I [Bacteroides uniformis].	23.43	542	328	19	3	520	5	483	2e-14	87.8
rs:WP_005016677	MULTISPECIES: topoisomerase I [Acinetobacter].	23.53	595	364	20	76	629	104	648	2e-14	87.8
rs:WP_023704548	MULTISPECIES: DNA topoisomerase I [Mesorhizobium].	22.54	701	404	26	1	630	1	633	2e-14	87.8
rs:WP_037000362	DNA topoisomerase I [Pseudomonas pseudoalcaligenes].	22.98	483	298	14	186	633	194	637	2e-14	87.8
tr:G3W4B1_SARHA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.35	426	246	18	188	585	115	496	2e-14	87.8
rs:WP_007430014	DNA topoisomerase I [Paenibacillus sp. Aloe-11].	22.97	566	374	20	103	636	80	615	2e-14	87.4
rs:WP_034428678	DNA topoisomerase I [Acinetobacter radioresistens].	23.53	595	364	20	76	629	104	648	2e-14	87.8
rs:WP_026770357	DNA topoisomerase I [Sediminibacterium sp. OR53].	25.97	543	321	21	3	525	5	486	2e-14	87.8
rs:WP_033562926	DNA topoisomerase I [Sphingobacteriaceae bacterium DW12].	25.16	473	288	13	74	520	51	483	2e-14	87.8
rs:WP_013549702	DNA topoisomerase I [Cellulophaga algicola].	28.53	375	231	12	157	521	132	479	2e-14	87.8
rs:WP_018869175	DNA topoisomerase I [Thioalkalivibrio sp. ALgr3].	22.45	579	339	17	3	534	5	520	2e-14	87.8
rs:WP_015349034	DNA topoisomerase I [Myxococcus stipitatus].	22.92	624	386	27	76	640	128	715	2e-14	87.8
rs:WP_042272078	DNA topoisomerase I [Clostridium sp. 01].	23.42	568	352	19	103	631	81	604	2e-14	87.4
rs:WP_015753783	DNA topoisomerase I [Robiginitalea biformata].	24.34	530	334	17	3	521	5	478	2e-14	87.8
rs:WP_028545144	DNA topoisomerase I [Paenibacillus taiwanensis].	22.92	589	379	23	88	636	62	615	2e-14	87.4
tr:I9PWE6_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	24.19	496	318	16	75	536	46	517	2e-14	87.0
rs:WP_003336897	DNA topoisomerase I [Brevibacillus laterosporus].	23.27	563	375	21	103	636	80	614	2e-14	87.4
rs:WP_013301081	DNA topoisomerase I [Parvularcula bermudensis].	22.21	698	443	30	1	647	1	649	2e-14	87.8
rs:WP_004697212	DNA topoisomerase I [Veillonella parvula].	22.81	570	366	20	95	629	142	672	2e-14	87.8
tr:A0A0E2Q2V1_STRTR	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:ETW89632.1};	22.72	559	361	21	103	630	108	626	2e-14	87.4
rs:WP_007680956	DNA topoisomerase I [Novosphingobium sp. AP12].	22.72	559	354	17	1	536	1	504	2e-14	87.8
rs:WP_039178505	DNA topoisomerase I [Bacillus sp. WP8].	23.93	514	331	21	154	636	130	614	2e-14	87.4
rs:WP_021488552	topoisomerase I [Pseudomonas mendocina].	23.19	483	297	13	186	633	195	638	2e-14	87.8
rs:WP_022223943	DNA topoisomerase [Clostridium sp. CAG:253].	23.30	558	361	19	90	616	67	588	2e-14	87.4
rs:WP_005899117	DNA topoisomerase I subunit omega [Aeromonas molluscorum].	22.03	531	336	18	187	680	193	682	2e-14	87.8
rs:WP_016597622	topoisomerase I, partial [Yersinia pestis].	22.51	533	318	16	187	673	60	543	2e-14	87.4
rs:WP_033131079	DNA topoisomerase I [Aeromonas sp. AE235].	23.60	606	366	22	75	633	82	637	2e-14	87.8
rs:WP_002360765	hypothetical protein, partial [Enterococcus faecium].	26.57	207	140	3	422	616	1	207	2e-14	84.0
rs:WP_041027941	DNA topoisomerase I, partial [Salmonella enterica].	24.48	482	311	16	73	533	74	523	2e-14	87.0
rs:WP_026512315	DNA topoisomerase I [Butyrivibrio sp. NC2007].	22.84	556	368	15	90	616	61	584	2e-14	87.4
rs:WP_005162646	DNA topoisomerase I [Acinetobacter sp. NIPH 284].	23.14	579	358	19	90	629	117	647	2e-14	87.8
rs:WP_011225888	DNA topoisomerase I [Streptococcus thermophilus].	22.72	559	361	21	103	630	108	626	2e-14	87.4
rs:XP_005745890	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X1 [Pundamilia nyererei].	21.90	621	374	24	3	564	5	573	2e-14	87.8
rs:WP_035544208	hypothetical protein, partial [Holospora elegans].	23.79	618	386	24	64	629	44	628	2e-14	87.4
rs:XP_003762778	PREDICTED: DNA topoisomerase 3-beta-1 [Sarcophilus harrisii].	25.35	426	246	18	188	585	151	532	2e-14	87.8
rs:WP_017677648	topoisomerase I [Pseudomonas alcaliphila].	23.19	483	297	13	186	633	195	638	2e-14	87.8
tr:L0DLK2_SINAD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.44	585	353	19	90	631	132	670	2e-14	87.8
rs:WP_026751491	DNA topoisomerase I [Sediminibacterium sp. C3].	24.80	625	375	23	3	600	5	561	2e-14	87.8
rs:WP_036161483	hypothetical protein [Lysinibacillus sphaericus].	31.58	190	114	3	141	317	1	187	2e-14	83.6
tr:A0A072TRW2_MEDTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.78	619	380	24	64	618	301	885	2e-14	87.8
rs:WP_024611339	DNA topoisomerase I [Pseudoalteromonas haloplanktis].	22.00	591	386	17	76	631	91	641	2e-14	87.8
rs:WP_027263490	DNA topoisomerase I [Sedimentitalea nanhaiensis].	25.96	520	313	18	55	537	27	511	2e-14	87.8
rs:XP_004088632	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-beta-1 [Nomascus leucogenys].	24.28	416	263	13	188	585	168	549	2e-14	87.8
rs:WP_009594778	DNA topoisomerase I [Paenibacillus sp. HGF5].	24.04	570	363	24	103	636	80	615	2e-14	87.4
rs:WP_027338521	DNA topoisomerase I [Helicobacter bilis].	23.00	626	384	24	55	629	24	602	2e-14	87.4
rs:WP_041108973	DNA topoisomerase I [Bacillus pumilus].	23.39	560	374	21	105	636	82	614	2e-14	87.4
tr:A0A0D9VPW5_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:LPERR03G04240.1};	22.00	641	394	27	3	585	12	604	2e-14	87.8
rs:WP_008662589	DNA topoisomerase I [Bacteroides sp. 4_1_36].	23.43	542	328	19	3	520	5	483	2e-14	87.8
rs:WP_022575798	topoisomerase I [Acinetobacter nosocomialis].	23.36	595	369	19	74	629	100	646	2e-14	87.8
rs:WP_005834437	MULTISPECIES: DNA topoisomerase I [Bacteroides].	23.43	542	328	19	3	520	5	483	2e-14	87.8
rs:WP_032118150	DNA topoisomerase I [Clostridium sp. CL-2].	23.03	647	402	18	2	616	4	586	2e-14	87.4
rs:WP_035575028	hypothetical protein, partial [Holospora undulata].	23.79	618	386	24	64	629	44	628	2e-14	87.4
rs:WP_041399266	DNA topoisomerase I [Sphaerobacter thermophilus].	21.41	682	421	21	3	630	1	621	2e-14	87.4
rs:WP_003679896	topoisomerase I [Lactobacillus coryniformis].	33.52	182	115	5	3	179	4	184	2e-14	83.6
rs:WP_011940495	DNA topoisomerase I [Geobacter uraniireducens].	23.19	720	422	28	3	658	5	657	2e-14	87.4
rs:WP_044467650	DNA topoisomerase I [Bacteroides uniformis].	23.43	542	328	19	3	520	5	483	2e-14	87.8
rs:WP_042101777	DNA topoisomerase III, partial [Escherichia coli].	35.04	117	66	4	1	113	1	111	2e-14	81.6
rs:WP_012535748	DNA topoisomerase I [Acidithiobacillus ferrooxidans].	22.26	584	389	19	85	630	62	618	2e-14	87.8
rs:WP_023833737	DNA topoisomerase I [Mesorhizobium sp. L103C105A0].	22.54	701	404	26	1	630	1	633	2e-14	87.8
rs:WP_007892424	topoisomerase I [Pantoea sp. GM01].	22.66	481	302	15	187	633	190	634	2e-14	87.8
rs:XP_002480564	DNA topoisomerase III, putative [Talaromyces stipitatus ATCC 10500].	22.36	653	380	24	3	573	7	614	2e-14	87.4
rs:WP_007808660	DNA topoisomerase I [Rhodanobacter spathiphylli].	22.86	503	321	13	77	538	54	530	2e-14	87.8
tr:A7V8S5_BACUN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.43	542	328	19	3	520	15	493	2e-14	87.8
rs:WP_032850443	DNA topoisomerase I [Bacteroides sp. 1_1_14].	23.52	506	328	16	38	526	18	481	2e-14	87.4
rs:WP_017725890	hypothetical protein, partial [Bacillus sp. L1(2012)].	36.55	145	83	4	487	627	12	151	2e-14	84.0
rs:WP_033416077	hypothetical protein, partial [Hahella ganghwensis].	24.22	512	319	19	55	538	27	497	2e-14	87.0
tr:G3W4B0_SARHA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.35	426	246	18	188	585	152	533	2e-14	87.4
tr:K2AAC1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.54	667	393	21	1	616	1	601	2e-14	87.4
rs:WP_045832147	DNA topoisomerase I [Pantoea sp. BL1].	23.38	479	301	15	187	633	190	634	2e-14	87.8
rs:WP_008565877	DNA topoisomerase I [Prevotella maculosa].	23.28	597	373	19	3	580	5	535	2e-14	87.4
rs:WP_026520741	DNA topoisomerase I [Butyrivibrio sp. VCB2001].	22.84	556	368	15	90	616	61	584	2e-14	87.4
rs:WP_023681566	DNA topoisomerase I [Mesorhizobium sp. LSJC277A00].	22.54	701	404	26	1	630	1	633	2e-14	87.8
rs:WP_029646113	DNA topoisomerase I, partial [Helicobacter pylori].	24.19	496	318	16	75	536	46	517	2e-14	87.0
rs:WP_015736334	DNA topoisomerase I [Paenibacillus sp. Y412MC10].	23.86	570	364	24	103	636	80	615	2e-14	87.4
rs:WP_011968523	DNA topoisomerase I [Clostridium beijerinckii].	24.27	651	389	27	2	616	4	586	2e-14	87.4
rs:XP_012337140	hypothetical protein AK88_04107 [Plasmodium fragile].	23.41	581	340	20	40	555	28	568	2e-14	87.0
rs:WP_005710553	DNA topoisomerase I [Lactobacillus rhamnosus].	23.74	577	366	19	90	629	68	607	2e-14	87.4
rs:WP_039489912	MULTISPECIES: DNA topoisomerase I [Pseudoalteromonas].	22.88	625	398	22	49	631	59	641	2e-14	87.8
tr:D1C7I9_SPHTD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.55	682	420	21	3	630	62	682	2e-14	87.4
rs:WP_041030303	DNA topoisomerase III, partial [Salmonella enterica].	33.09	136	79	5	1	130	1	130	2e-14	81.6
rs:WP_045717563	DNA topoisomerase III, partial [Salmonella enterica].	33.09	136	79	5	1	130	1	130	2e-14	82.4
rs:WP_039207818	hypothetical protein, partial [Anaerovibrio lipolyticus].	24.12	485	309	17	163	616	168	624	2e-14	87.4
rs:WP_007685816	DNA topoisomerase I [Sphingobium indicum].	21.69	687	419	25	1	629	1	626	2e-14	87.4
rs:WP_008295426	topoisomerase I [Congregibacter litoralis].	22.47	592	388	19	72	629	86	640	2e-14	87.8
rs:WP_046175067	DNA topoisomerase I [Domibacillus indicus].	22.34	555	371	17	105	629	82	606	2e-14	87.4
rs:WP_018526855	hypothetical protein [Spirochaeta alkalica].	23.66	503	310	16	77	538	69	538	2e-14	87.4
rs:WP_035055313	DNA topoisomerase I, partial [Desulfuromonas sp. TF].	23.97	680	396	29	3	630	5	615	2e-14	87.4
rs:XP_002436546	hypothetical protein SORBIDRAFT_10g004493, partial [Sorghum bicolor].	23.23	637	385	27	39	610	332	929	2e-14	87.8
rs:WP_022506394	DNA topoisomerase [Eubacterium sp. CAG:581].	23.62	580	364	21	76	616	52	591	2e-14	87.4
rs:WP_025613743	DNA topoisomerase I [Cellulophaga baltica].	25.28	530	330	16	3	521	5	479	2e-14	87.4
rs:XP_002121520	PREDICTED: DNA topoisomerase 3-beta-1 [Ciona intestinalis].	22.73	462	312	11	188	631	150	584	2e-14	87.4
rs:XP_007623023	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Cricetulus griseus].	24.88	414	263	14	188	585	76	457	2e-14	87.4
rs:WP_045715638	DNA topoisomerase III, partial [Salmonella enterica].	33.09	136	79	5	1	130	1	130	2e-14	82.4
tr:I1FRL5_AMPQE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.46	635	400	24	46	631	66	663	2e-14	87.8
rs:WP_012848405	MULTISPECIES: topoisomerase I [Edwardsiella].	24.26	606	362	23	75	633	79	634	2e-14	87.4
tr:E6N9Z0_9ARCH	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:BAJ49146.1}; EC=5.99.1.2 {ECO:0000313|EMBL:BAJ49146.1};	22.06	621	398	17	3	587	16	586	2e-14	87.0
rs:WP_029507317	DNA topoisomerase I [Lactobacillus animalis].	24.06	586	349	22	103	642	73	608	2e-14	87.4
rs:WP_013945052	DNA topoisomerase I [Treponema paraluiscuniculi].	23.58	458	297	12	186	618	175	604	2e-14	87.4
rs:XP_003655718	hypothetical protein THITE_2119715 [Thielavia terrestris NRRL 8126].	22.67	569	349	23	3	524	5	529	2e-14	87.4
rs:WP_011227156	DNA topoisomerase I [Streptococcus thermophilus].	22.72	559	361	21	103	630	108	626	2e-14	87.4
rs:WP_022446921	DNA topoisomerase [Faecalibacterium sp. CAG:74].	22.39	670	417	26	2	630	7	614	2e-14	87.4
rs:WP_019424975	DNA topoisomerase I [Paenibacillus sp. OSY-SE].	22.35	586	386	21	88	636	62	615	2e-14	87.4
rs:WP_038214901	DNA topoisomerase I [Xenorhabdus bovienii].	24.33	485	289	17	187	633	188	632	2e-14	87.4
tr:K1ZI81_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.44	577	345	21	82	612	59	590	2e-14	87.4
rs:WP_038344890	DNA topoisomerase I [Acinetobacter sp. A47].	23.47	571	366	16	90	629	117	647	2e-14	87.4
rs:WP_027395008	DNA topoisomerase I [Aquimarina latercula].	26.72	539	318	22	3	526	5	481	2e-14	87.4
tr:A1U7T2_MARHV	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:ABM21051.1}; EC=5.99.1.2 {ECO:0000313|EMBL:ABM21051.1};	22.41	531	343	16	15	523	1	484	2e-14	87.4
rs:WP_046859941	DNA topoisomerase I [Sedimenticola sp. SIP-G1].	22.67	675	419	28	1	630	1	617	2e-14	87.4
rs:WP_035217216	hypothetical protein, partial [Acidithiobacillus thiooxidans].	25.58	473	289	17	90	537	65	499	2e-14	87.0
rs:WP_026518886	DNA topoisomerase I [Butyrivibrio sp. FCS006].	22.84	556	368	15	90	616	61	584	2e-14	87.4
rs:WP_037502696	DNA topoisomerase I [Sphingobacterium sp. ACCC 05744].	23.73	472	292	15	76	520	53	483	2e-14	87.4
rs:WP_038186134	DNA topoisomerase I [Vibrio rhizosphaerae].	23.49	613	357	22	75	633	86	640	2e-14	87.4
rs:WP_002847138	DNA topoisomerase I [Ruminococcus albus].	24.18	579	350	21	97	629	73	608	2e-14	87.4
rs:WP_004869654	DNA topoisomerase I [Acidithiobacillus caldus].	21.92	584	391	18	85	630	62	618	2e-14	87.4
rs:WP_002959733	topoisomerase I [Pseudoalteromonas haloplanktis].	22.88	625	398	22	49	631	59	641	2e-14	87.4
rs:WP_026098772	DNA topoisomerase I [Oscillatoria sp. PCC 10802].	22.15	641	373	21	3	580	4	581	2e-14	87.4
rs:XP_004574243	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Maylandia zebra].	22.11	615	380	20	3	564	5	573	2e-14	87.4
rs:WP_019808041	DNA topoisomerase I [Osedax symbiont Rs1].	22.58	589	375	18	76	629	93	635	2e-14	87.4
rs:WP_039174320	DNA topoisomerase I [Leisingera sp. ANG-S5].	22.71	700	414	29	1	630	1	643	2e-14	87.4
rs:WP_010687784	DNA topoisomerase I [Leuconostoc gelidum].	22.41	540	359	16	103	616	103	608	2e-14	87.4
rs:WP_022354894	DNA topoisomerase [Bacteroides sp. CAG:875].	23.03	534	345	15	3	526	5	482	2e-14	87.4
rs:XP_002970788	hypothetical protein SELMODRAFT_94303 [Selaginella moellendorffii].	21.92	666	410	23	3	617	6	612	2e-14	87.4
rs:WP_046493073	DNA topoisomerase I [Candidatus Hamiltonella defensa].	22.71	590	391	16	74	633	82	636	2e-14	87.4
tr:M8C938_AEGTA	SubName: Full=DNA topoisomerase 3-beta-1 {ECO:0000313|EMBL:EMT11643.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:EMT11643};	21.47	652	409	26	18	614	6	609	2e-14	87.4
rs:WP_023751519	DNA topoisomerase I [Mesorhizobium sp. LNJC380A00].	23.34	647	385	24	55	630	27	633	2e-14	87.4
rs:WP_004323094	MULTISPECIES: DNA topoisomerase I [Bacteroides].	24.68	470	298	16	77	526	54	487	2e-14	87.4
rs:WP_023178015	MULTISPECIES: DNA topoisomerase I [Carnobacterium].	23.16	583	375	21	90	635	68	614	2e-14	87.0
rs:WP_014203113	DNA topoisomerase I [Owenweeksia hongkongensis].	24.13	460	297	12	157	600	132	555	2e-14	87.4
rs:WP_012231710	DNA topoisomerase I [Bartonella tribocorum].	24.11	643	384	25	55	629	27	633	2e-14	87.4
tr:J9H0M7_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EJX09208.1};	22.84	543	340	19	3	526	15	497	2e-14	87.4
rs:WP_038649991	DNA topoisomerase I [Roseibacterium elongatum].	21.87	718	419	23	1	630	1	664	2e-14	87.4
rs:XP_003386887	PREDICTED: DNA topoisomerase 3-alpha-like [Amphimedon queenslandica].	24.22	479	299	17	188	631	214	663	2e-14	87.4
tr:D6SQD4_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.58	670	418	26	3	639	12	620	2e-14	87.4
rs:WP_047093970	DNA topoisomerase I [Erythrobacter marinus].	21.89	699	426	24	1	644	1	634	2e-14	87.4
rs:WP_017826122	DNA topoisomerase I [Clostridium botulinum].	23.93	606	376	25	103	671	80	637	2e-14	87.0
rs:WP_022332091	DNA topoisomerase [Alistipes sp. CAG:29].	23.32	536	333	18	3	520	5	480	2e-14	87.4
rs:XP_001896443	DNA topoisomerase III beta-1 [Brugia malayi].	22.47	681	432	26	3	629	7	645	2e-14	87.4
rs:WP_034336155	DNA topoisomerase I [Commensalibacter sp. MX01].	23.49	630	405	22	55	629	28	635	2e-14	87.4
rs:WP_008286846	reverse gyrase [Hydrogenivirga sp. 128-5-R1-1].	23.45	614	370	21	3	589	598	1138	2e-14	87.8
rs:WP_003797825	DNA topoisomerase I [Kingella oralis].	22.39	585	380	15	64	611	46	593	2e-14	87.4
tr:W0RPS3_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.30	588	369	22	90	629	124	677	2e-14	87.4
rs:WP_002418302	hypothetical protein, partial [Enterococcus faecalis].	38.46	143	78	4	84	218	1	141	2e-14	82.0
gp:AP012344_1927	conserved hypothetical protein [Helicobacter cinaedi PAGU611]	23.00	513	330	15	103	575	41	528	2e-14	87.0
rs:WP_045096318	DNA topoisomerase I [Legionella fallonii].	24.36	624	391	29	55	630	29	619	2e-14	87.4
rs:WP_034303584	DNA topoisomerase III, partial [Bacillus sp. 123MFChir2].	24.68	316	210	8	360	655	7	314	2e-14	85.1
rs:WP_040190181	DNA topoisomerase I [Leuconostoc citreum].	23.21	560	363	20	88	616	84	607	2e-14	87.0
rs:WP_013604017	reverse gyrase [Vulcanisaeta moutnovskia].	23.05	629	376	26	4	588	695	1259	2e-14	87.8
rs:WP_041657431	DNA topoisomerase I, partial [Marinobacter hydrocarbonoclasticus].	22.41	531	343	16	15	523	1	484	2e-14	87.0
rs:WP_036593494	topoisomerase I, partial [Oenococcus kitaharae].	28.95	152	106	1	432	581	18	169	2e-14	84.3
rs:WP_016305480	DNA topoisomerase I [Lachnospiraceae bacterium A2].	22.94	558	364	15	90	616	67	589	2e-14	87.0
gp:CP003784_594	DNA topoisomerase I [Bartonella quintana RM-11]	22.64	698	406	27	1	629	1	633	2e-14	87.4
tr:G5GLW4_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.02	672	423	22	3	636	5	613	2e-14	87.0
rs:WP_029573099	DNA topoisomerase I, partial [Pseudomonas syringae].	24.27	478	310	15	74	533	87	530	2e-14	86.7
rs:WP_035421699	DNA topoisomerase I [Lactobacillus florum].	23.16	583	371	20	83	629	78	619	2e-14	87.0
rs:WP_033858678	DNA topoisomerase III, partial [Staphylococcus aureus].	34.94	166	95	5	3	163	4	161	2e-14	82.4
rs:WP_017210743	DNA topoisomerase I [Clostridium beijerinckii].	24.92	654	381	27	2	616	4	586	2e-14	87.0
rs:WP_018035879	hypothetical protein [Marine Group II euryarchaeote SCGC AB-629-J06].	25.47	479	291	17	77	527	53	493	2e-14	87.4
rs:WP_039957093	DNA topoisomerase I [Selenomonas infelix].	22.02	672	423	22	3	636	21	629	2e-14	87.0
rs:WP_019298345	MULTISPECIES: DNA topoisomerase I [Leisingera].	22.71	700	414	29	1	630	1	643	2e-14	87.4
rs:WP_037245763	DNA topoisomerase I [Roseovarius sp. MCTG156(2b)].	21.67	706	418	26	1	629	1	648	2e-14	87.4
rs:WP_026479789	DNA topoisomerase I [Ahrensia sp. 13_GOM-1096m].	23.54	718	426	28	1	655	1	658	2e-14	87.4
rs:WP_023628782	DNA topoisomerase I [Pseudomonas mosselii].	23.23	564	355	16	84	611	69	590	2e-14	87.0
tr:D7IEM3_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.04	470	307	13	74	526	15	451	2e-14	87.0
rs:WP_014779492	DNA topoisomerase I [Thiocystis violascens].	23.13	601	383	23	76	630	51	618	2e-14	87.0
rs:WP_026914641	DNA topoisomerase I [Gramella portivictoriae].	25.52	529	328	17	3	521	5	477	2e-14	87.4
rs:WP_008627226	DNA topoisomerase I [Paraprevotella xylaniphila].	23.79	660	399	25	3	616	5	606	2e-14	87.4
rs:WP_025059920	DNA topoisomerase I [Sulfitobacter donghicola].	23.38	603	340	20	1	534	1	550	2e-14	87.4
tr:W0DWL7_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	22.65	565	355	17	55	593	27	535	2e-14	87.0
rs:WP_020075496	DNA topoisomerase I [Cryocola sp. 340MFSha3.1].	24.56	631	355	26	2	565	6	582	2e-14	87.4
rs:WP_042396551	DNA topoisomerase I [Clostridium sp. JCC].	25.37	544	343	18	103	618	80	588	2e-14	87.0
rs:WP_042744585	topoisomerase I, partial [Oenococcus oeni].	26.55	226	144	5	276	489	3	218	2e-14	83.6
rs:WP_009032645	DNA topoisomerase I [Indibacter alkaliphilus].	26.72	539	310	22	3	520	5	479	2e-14	87.0
rs:WP_005010707	DNA topoisomerase I [Nitrospina gracilis].	24.11	593	349	20	83	634	60	592	2e-14	87.0
tr:V6TP11_GIAIN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESU40102.1}; Flags: Fragment;	27.01	422	262	19	188	574	113	523	2e-14	87.4
rs:WP_022339030	DNA topoisomerase [Bacteroides sp. CAG:714].	21.75	630	405	20	3	617	5	561	2e-14	87.0
rs:WP_033047072	hypothetical protein, partial [Clostridium botulinum].	33.88	183	107	7	2	176	3	179	2e-14	83.2
rs:WP_007786297	DNA topoisomerase I [Desulfosporosinus youngiae].	23.19	634	392	26	88	675	62	646	2e-14	87.0
rs:WP_023763638	DNA topoisomerase I [Mesorhizobium sp. LNHC232B00].	21.86	700	410	23	1	630	1	633	2e-14	87.4
rs:WP_022984562	topoisomerase I [Alcanivorax sp. P2S70].	22.46	610	391	23	65	631	79	649	2e-14	87.4
tr:A0A0C3HUV8_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIN06022.1};	22.44	557	355	18	3	520	6	524	2e-14	87.0
rs:XP_008573019	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Galeopterus variegatus].	23.43	414	269	12	188	585	168	549	2e-14	87.0
rs:WP_038040953	DNA topoisomerase I [Thermomicrobiales bacterium KI4].	23.64	605	375	23	83	638	55	621	2e-14	87.0
rs:WP_032563899	DNA topoisomerase I, partial [Bacteroides fragilis].	37.50	128	63	3	1	117	1	122	2e-14	82.0
tr:J5U251_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.30	575	355	21	100	635	50	577	2e-14	87.0
rs:WP_044038350	DNA topoisomerase I [Clostridium sp. M2/40].	25.17	572	350	20	83	616	60	591	2e-14	87.0
rs:WP_009181788	DNA topoisomerase I [Desulfovibrio sp. FW1012B].	23.91	594	367	21	76	629	53	601	2e-14	87.0
tr:F6ST44_CIOIN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.73	462	312	11	188	631	177	611	2e-14	87.0
rs:WP_034566021	DNA topoisomerase I [Helicobacter bilis].	23.00	626	384	24	55	629	24	602	2e-14	87.0
rs:WP_023701185	DNA topoisomerase I [Mesorhizobium sp. LSJC264A00].	22.40	701	405	26	1	630	1	633	2e-14	87.4
rs:WP_029516985	DNA topoisomerase I [Paenibacillus polymyxa].	22.97	566	374	20	103	636	80	615	2e-14	87.0
rs:WP_004867042	DNA topoisomerase I [Bartonella vinsonii].	23.50	698	400	27	1	629	1	633	2e-14	87.4
rs:WP_028491545	DNA topoisomerase I [Thioalkalivibrio sp. ALE19].	22.45	579	339	17	3	534	5	520	2e-14	87.4
rs:WP_039189441	DNA topoisomerase I [Leisingera sp. ANG-M6].	22.71	700	414	29	1	630	1	643	2e-14	87.4
rs:WP_011366282	DNA topoisomerase I [Desulfovibrio alaskensis].	22.56	656	394	24	77	672	54	655	2e-14	87.0
rs:WP_026808340	MULTISPECIES: DNA topoisomerase I [Arcobacter].	24.32	658	394	24	3	617	4	600	2e-14	87.0
tr:H8ZDZ0_NEMS1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.29	637	413	18	3	602	4	595	2e-14	87.0
rs:WP_024905748	hypothetical protein [Burkholderia andropogonis].	32.53	166	102	4	459	614	91	256	2e-14	84.7
tr:Z2EZT6_VIBPH	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EVU20835.1};	35.20	125	81	0	457	581	28	152	2e-14	83.2
rs:WP_022043262	DNA topoisomerase [Bacteroides caccae CAG:21].	23.42	619	382	20	3	596	5	556	2e-14	87.0
rs:WP_032054351	DNA topoisomerase I [Acinetobacter baumannii].	22.55	572	370	17	90	629	116	646	2e-14	87.4
tr:A0A072TFG8_MEDTR	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	22.78	619	380	24	64	618	301	885	2e-14	87.4
rs:WP_003623892	DNA topoisomerase I [Lactobacillus delbrueckii].	22.32	551	371	15	90	616	100	617	2e-14	87.0
rs:WP_047164149	DNA topoisomerase I [Trichodesmium erythraeum].	23.44	627	364	23	3	571	4	572	2e-14	87.4
rs:WP_018189947	DNA topoisomerase I [Leifsonia sp. 109].	24.56	631	355	26	2	565	6	582	2e-14	87.4
rs:WP_033765814	DNA topoisomerase I [Helicobacter pylori].	24.39	492	322	14	75	536	46	517	2e-14	87.0
rs:WP_021667426	DNA topoisomerase I [Porphyromonas sp. oral taxon 278].	24.11	589	377	22	1	578	1	530	2e-14	87.0
rs:WP_004899760	DNA topoisomerase I [Leuconostoc citreum].	23.21	560	363	20	88	616	84	607	2e-14	87.0
rs:WP_026956978	DNA topoisomerase I [Algoriphagus vanfongensis].	26.87	402	237	12	3	392	5	361	2e-14	87.0
rs:WP_013748699	endonuclease [Pyrococcus sp. NA2].	27.42	361	205	18	307	640	682	1012	3e-14	87.4
rs:WP_013748699	endonuclease [Pyrococcus sp. NA2].	25.53	329	215	10	1	310	1	318	2e-12	81.3
rs:WP_011964077	DNA topoisomerase I [Flavobacterium psychrophilum].	24.39	533	329	22	3	521	5	477	3e-14	87.0
rs:WP_026320092	DNA topoisomerase I [Bacteroides barnesiae].	21.75	630	405	20	3	617	5	561	3e-14	87.0
rs:WP_003370835	DNA topoisomerase I [Clostridium botulinum].	24.18	546	343	21	103	616	80	586	3e-14	87.0
rs:WP_028950848	reverse gyrase [Sulfurihydrogenibium subterraneum].	24.01	608	371	22	3	587	598	1137	3e-14	87.4
rs:WP_015266922	DNA topoisomerase I [Echinicola vietnamensis].	24.91	538	321	17	3	520	5	479	3e-14	87.0
rs:WP_029635180	DNA topoisomerase I [[Scytonema hofmanni] UTEX B 1581].	22.03	622	385	16	3	574	4	575	3e-14	87.0
rs:WP_000520735	hypothetical protein, partial [Bacillus thuringiensis].	30.56	216	128	7	3	204	5	212	3e-14	83.2
rs:WP_037165268	MULTISPECIES: DNA topoisomerase I [Rhizobium].	24.43	659	366	32	55	630	27	636	3e-14	87.0
rs:WP_018935946	DNA topoisomerase I [Thioalkalivibrio sp. ALJ24].	22.49	578	340	17	3	534	5	520	3e-14	87.0
rs:WP_046179161	DNA topoisomerase I [Domibacillus sp. PAMC 80007].	22.08	557	370	18	105	629	82	606	3e-14	87.0
rs:WP_012111753	DNA topoisomerase I [Parvibaculum lavamentivorans].	21.94	638	401	25	55	629	27	630	3e-14	87.0
rs:WP_011900829	DNA topoisomerase [Pyrobaculum arsenaticum].	20.98	615	419	17	1	585	1	578	3e-14	86.7
rs:WP_016660865	DNA topoisomerase I [Bacteroides stercoris].	23.89	628	368	25	3	596	5	556	3e-14	87.0
rs:WP_038936326	DNA topoisomerase I [Bradyrhizobium japonicum].	22.59	686	421	23	1	630	1	632	3e-14	87.0
rs:WP_022503383	DNA topoisomerase [Mycoplasma sp. CAG:776].	23.48	707	448	24	2	682	3	642	3e-14	87.0
rs:WP_004307878	MULTISPECIES: DNA topoisomerase I [Bacteroides].	23.24	598	372	20	3	580	5	535	3e-14	87.0
rs:WP_021921659	DNA topoisomerase [Acholeplasma sp. CAG:878].	23.12	653	413	23	3	629	4	593	3e-14	87.0
tr:K2BFF1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.74	657	392	20	1	609	1	596	3e-14	87.0
rs:XP_009353312	PREDICTED: uncharacterized protein LOC103944567 isoform X1 [Pyrus x bretschneideri].	22.98	605	381	26	64	610	412	989	3e-14	87.4
rs:WP_025229321	hypothetical protein [Fimbriimonas ginsengisoli].	23.70	595	339	24	2	530	4	549	3e-14	87.0
rs:WP_002661675	DNA topoisomerase I [Bergeyella zoohelcum].	24.44	630	383	24	3	611	5	562	3e-14	87.0
rs:WP_011770299	topoisomerase I [Psychromonas ingrahamii].	23.68	604	373	21	73	633	85	643	3e-14	87.0
tr:W7C9U0_BROTH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	22.64	477	301	18	188	629	1	444	3e-14	86.3
rs:WP_023973319	DNA topoisomerase I [Clostridium pasteurianum].	24.42	651	388	28	2	616	4	586	3e-14	87.0
rs:WP_016174777	DNA topoisomerase 1 [Enterococcus saccharolyticus].	23.55	569	364	21	103	635	81	614	3e-14	87.0
tr:A0A0D6AJC9_9CHRO	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:BAQ62928.1};	24.52	628	362	25	3	574	4	575	3e-14	87.0
rs:WP_020044548	DNA topoisomerase I [alpha proteobacterium SCGC AAA298-K06].	23.20	681	414	27	1	630	1	623	3e-14	87.0
rs:WP_012623949	DNA topoisomerase I [Desulfovibrio desulfuricans].	23.14	605	382	21	76	640	53	614	3e-14	87.0
rs:WP_008776858	DNA topoisomerase I [Bacteroides sp. 2_2_4].	24.68	470	298	16	77	526	54	487	3e-14	87.0
rs:WP_022104140	DNA topoisomerase [Bacteroides stercoris CAG:120].	23.72	624	374	24	3	596	5	556	3e-14	87.0
rs:WP_040760362	DNA topoisomerase I [Weissella paramesenteroides].	23.06	733	433	26	3	683	22	675	3e-14	87.0
rs:WP_029061438	DNA topoisomerase I [Labrenzia sp. DG1229].	24.76	634	350	28	1	574	1	567	3e-14	87.0
rs:WP_014494702	DNA topoisomerase I [Bradyrhizobium japonicum].	22.59	686	421	23	1	630	1	632	3e-14	87.0
rs:WP_041772386	DNA topoisomerase [Leptospirillum ferriphilum].	23.21	672	414	29	3	631	11	623	3e-14	87.0
rs:WP_027239369	DNA topoisomerase I [Pseudophaeobacter arcticus].	23.65	702	407	31	1	630	1	645	3e-14	87.0
rs:WP_016775814	DNA topoisomerase I [Anaerophaga thermohalophila].	24.68	543	317	20	3	520	12	487	3e-14	87.0
rs:WP_022096555	DNA topoisomerase [Streptococcus thermophilus CAG:236].	22.54	559	362	21	103	630	108	626	3e-14	87.0
rs:WP_026893862	DNA topoisomerase I [Clostridiisalibacter paucivorans].	23.70	709	436	25	3	675	5	644	3e-14	86.7
rs:XP_005949419	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X1 [Haplochromis burtoni].	22.28	615	379	21	3	564	5	573	3e-14	86.7
rs:WP_035390023	DNA topoisomerase I [Ferrimicrobium acidiphilum].	23.58	598	331	21	3	530	5	546	3e-14	87.0
rs:WP_006562565	DNA topoisomerase I [Oscillochloris trichoides].	23.80	584	353	17	83	612	58	603	3e-14	87.0
tr:A0A072TH66_MEDTR	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	22.78	619	380	24	64	618	301	885	3e-14	87.4
rs:WP_012858472	DNA topoisomerase I [Streptobacillus moniliformis].	24.46	601	368	19	3	578	5	544	3e-14	87.0
rs:WP_044565945	DNA topoisomerase I [Anaerococcus sp. 9402080].	24.22	673	387	28	3	630	5	599	3e-14	86.7
gp:FP929058_741	DNA topoisomerase I [Enterococcus sp. 7L76]	25.57	481	299	19	103	554	81	531	3e-14	86.3
tr:A0A061I5V8_CRIGR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.88	414	263	14	188	585	143	524	3e-14	87.0
tr:A0A0D6ZGG3_LACDE	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KIY24607.1};	22.71	568	379	16	90	630	100	634	3e-14	87.0
rs:WP_039163689	DNA topoisomerase I [Leisingera sp. ANG-M1].	22.09	697	422	25	1	630	1	643	3e-14	87.0
rs:WP_040316003	DNA topoisomerase I [Bacteroides stercoris].	23.72	624	374	24	3	596	5	556	3e-14	87.0
tr:A0A072V0B5_MEDTR	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	22.28	552	372	13	105	631	55	574	3e-14	87.0
rs:WP_019591561	DNA topoisomerase I [Thioalkalivibrio sp. ALE20].	22.45	579	339	17	3	534	5	520	3e-14	87.0
tr:A0A060CQW3_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	24.03	491	325	13	75	536	46	517	3e-14	86.7
rs:WP_002686763	DNA topoisomerase I [Bergeyella zoohelcum].	24.01	629	387	23	3	611	5	562	3e-14	87.0
rs:WP_031897066	DNA topoisomerase III, partial [Staphylococcus aureus].	24.62	329	230	8	309	625	1	323	3e-14	84.3
tr:U5NGH4_9MOLU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00003390}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.09	660	385	24	33	629	15	621	3e-14	87.0
tr:G5PA46_SALET	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EHC66864.1};	33.09	136	79	5	1	130	1	130	3e-14	82.4
rs:WP_036728588	DNA topoisomerase I [Peptoniphilus sp. ChDC B134].	23.64	626	393	24	90	678	67	644	3e-14	86.7
rs:WP_010346391	DNA topoisomerase I [Paenibacillus peoriae].	22.97	566	374	20	103	636	80	615	3e-14	86.7
tr:A0A061JG33_9RICK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.05	499	304	18	75	533	52	520	3e-14	87.0
rs:WP_008106525	topoisomerase I [Pantoea sp. YR343].	23.01	478	304	16	187	633	190	634	3e-14	87.0
rs:WP_036156769	DNA topoisomerase I [Maribacter forsetii].	25.48	526	334	15	3	521	5	479	3e-14	87.0
rs:WP_022032109	DNA topoisomerase [Clostridium hathewayi CAG:224].	23.85	566	351	20	90	616	67	591	3e-14	86.7
rs:WP_028719490	DNA topoisomerase I [Paracoccus yeei].	22.53	697	428	27	1	648	1	634	3e-14	87.0
rs:WP_031556969	DNA topoisomerase I [Lachnospiraceae bacterium FD2005].	22.74	554	371	16	90	616	67	590	3e-14	86.7
rs:WP_039108965	DNA topoisomerase I [Flavobacterium sp. AED].	24.02	533	331	18	3	521	5	477	3e-14	87.0
rs:WP_043580749	DNA topoisomerase I [Gemmatimonas sp. AP64].	24.12	568	356	20	90	614	61	596	3e-14	87.0
rs:WP_025277018	DNA topoisomerase I [Helicobacter pylori].	24.13	634	405	22	75	658	46	653	3e-14	86.7
rs:WP_037948397	DNA topoisomerase I [Sulfuricurvum sp. MLSB].	22.34	649	402	23	1	616	1	580	3e-14	86.7
tr:A0A0C7GC68_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.25	569	347	20	103	631	81	605	3e-14	86.7
rs:WP_003167051	DNA topoisomerase I [Brevundimonas diminuta].	22.58	558	337	18	1	520	1	501	3e-14	87.0
tr:K2EKG9_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.58	670	410	28	1	629	1	609	3e-14	86.7
rs:WP_014027527	DNA topoisomerase I [Acidithiobacillus ferrivorans].	22.73	594	374	22	85	630	62	618	3e-14	87.0
rs:WP_039274721	DNA topoisomerase I [Paenibacillus polymyxa].	22.97	566	374	20	103	636	80	615	3e-14	86.7
rs:WP_028459321	DNA topoisomerase I [Chloroflexus sp. Y-396-1].	23.49	579	360	19	83	612	58	602	3e-14	87.0
rs:WP_047309161	DNA topoisomerase I [Rhodopseudomonas palustris].	23.48	690	411	29	1	630	1	633	3e-14	87.0
tr:F8PV61_SERL3	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.22	633	378	25	3	577	4	586	3e-14	87.0
rs:WP_038506612	DNA topoisomerase [Leptospirillum ferriphilum].	23.07	672	415	29	3	631	1	613	3e-14	87.0
rs:WP_028155046	DNA topoisomerase I [Bradyrhizobium japonicum].	22.59	686	421	23	1	630	1	632	3e-14	87.0
tr:G5Q3L4_SALMO	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EHC78614.1};	33.09	136	79	5	1	130	1	130	3e-14	82.4
rs:WP_010845973	DNA topoisomerase 1 [Xenorhabdus nematophila].	23.08	533	315	20	187	673	190	673	3e-14	87.0
rs:WP_015140537	DNA topoisomerase I [Nostoc sp. PCC 7524].	24.10	581	358	22	79	614	59	601	3e-14	86.7
rs:WP_038958010	DNA topoisomerase I [Bradyrhizobium japonicum].	22.59	686	421	23	1	630	1	632	3e-14	87.0
rs:WP_024307541	DNA topoisomerase I [Pseudomonas sp. P818].	22.89	485	296	13	186	633	194	637	3e-14	87.0
rs:WP_021071562	DNA topoisomerase I [Sphingobacterium paucimobilis].	23.54	514	321	17	31	520	18	483	3e-14	87.0
rs:WP_027433127	DNA topoisomerase I [Lachnospiraceae bacterium MD2004].	22.64	552	374	14	90	616	67	590	3e-14	86.7
tr:D4C6E9_9CLOT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EFE14137.1};	29.08	196	129	4	497	683	14	208	3e-14	83.2
rs:WP_014452033	reverse gyrase [Fervidobacterium pennivorans].	21.24	565	343	20	3	536	603	1096	3e-14	87.0
rs:WP_004837938	hypothetical protein, partial [Anaerococcus tetradius].	34.48	145	78	3	258	396	17	150	3e-14	81.6
rs:WP_034321765	DNA topoisomerase I [Helicobacter trogontum].	23.44	627	383	28	55	629	24	605	3e-14	86.7
rs:WP_042840451	DNA topoisomerase I, partial [Salmonella enterica].	24.57	411	253	14	252	633	48	430	3e-14	86.7
rs:XP_002111020	hypothetical protein TRIADDRAFT_22834 [Trichoplax adhaerens].	21.37	571	373	17	35	573	49	575	3e-14	86.7
rs:WP_035406961	DNA topoisomerase I [Exiguobacterium sp. RIT341].	22.54	661	421	24	3	630	5	607	3e-14	86.7
rs:WP_014727521	DNA topoisomerase I [Streptococcus thermophilus].	22.54	559	362	21	103	630	108	626	3e-14	86.7
rs:WP_026960310	DNA topoisomerase I [Aliagarivorans taiwanensis].	24.01	608	368	23	72	633	82	641	3e-14	87.0
rs:WP_033517008	DNA topoisomerase I [Bifidobacterium cuniculi].	22.81	627	377	21	2	571	6	582	3e-14	87.0
rs:WP_038357410	DNA topoisomerase I, partial [Bacillus anthracis].	25.44	397	267	13	105	480	82	470	3e-14	85.9
rs:WP_014608256	DNA topoisomerase I [Streptococcus thermophilus].	22.54	559	362	21	103	630	108	626	3e-14	86.7
rs:WP_009112799	topoisomerase I [Brenneria sp. EniD312].	22.19	649	401	20	74	673	80	673	3e-14	87.0
rs:WP_009166274	DNA topoisomerase I [Lactobacillus florum].	22.97	579	377	20	83	629	78	619	3e-14	86.7
rs:WP_034915031	DNA topoisomerase III, partial [Candidatus Accumulibacter sp. BA-91].	30.43	184	111	5	2	178	4	177	3e-14	82.4
rs:WP_034533897	DNA topoisomerase I [Lactobacillus kunkeei].	23.79	559	357	22	103	629	95	616	3e-14	86.7
rs:WP_046938354	DNA topoisomerase III, partial [Xanthomonas perforans].	29.12	182	118	5	1	179	1	174	3e-14	82.4
rs:WP_043896112	DNA topoisomerase I [Mycoplasma parvum].	24.09	660	385	24	33	629	19	625	3e-14	86.7
rs:WP_044132021	DNA topoisomerase I, partial [Bacteroides fragilis].	24.74	473	300	16	74	526	2	438	3e-14	85.5
rs:WP_023957456	DNA topoisomerase I [Paenibacillus sp. JCM 10914].	23.73	569	366	22	103	636	80	615	3e-14	86.7
rs:XP_005707982	DNA topoisomerase I [Galdieria sulphuraria].	25.21	587	312	23	77	578	171	715	3e-14	87.0
rs:WP_028911148	DNA topoisomerase I [Prevotella sp. MA2016].	23.13	601	368	21	3	580	5	534	3e-14	86.7
rs:XP_003459054	PREDICTED: DNA topoisomerase 3-beta-1 isoformX1 [Oreochromis niloticus].	22.02	613	383	20	3	564	5	573	3e-14	87.0
tr:E9YZQ1_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.36	595	377	25	73	635	88	635	3e-14	86.7
sp:TOP3A_ORYSJ	RecName: Full=DNA topoisomerase 3-alpha; EC=5.99.1.2;	21.56	733	445	31	3	653	13	697	3e-14	87.0
rs:WP_004864071	DNA topoisomerase I [Bartonella vinsonii].	23.50	698	400	27	1	629	1	633	3e-14	87.0
rs:WP_024329307	DNA topoisomerase I [Thioalkalivibrio sp. ALR17-21].	22.45	579	339	17	3	534	5	520	3e-14	87.0
rs:WP_029963009	hypothetical protein, partial [Aerophobetes bacterium SCGC AAA255-F10].	25.71	525	318	23	149	639	46	532	3e-14	86.3
rs:WP_028575888	DNA topoisomerase I [Desulfonatronovibrio hydrogenovorans].	23.98	588	364	24	83	631	60	603	3e-14	86.7
rs:WP_038036917	DNA topoisomerase I, partial [Thermopetrobacter sp. TC1].	23.87	687	409	31	3	630	4	635	3e-14	86.7
rs:WP_010249084	DNA topoisomerase I [Acetivibrio cellulolyticus].	23.74	556	363	17	90	616	67	590	3e-14	86.7
rs:WP_039772254	DNA topoisomerase I [Clostridium diolis].	24.31	650	390	27	2	616	4	586	3e-14	86.7
rs:WP_017365594	DNA topoisomerase I [Methylococcus capsulatus].	22.88	743	441	31	3	682	5	678	3e-14	86.7
rs:WP_023169833	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	24.48	482	311	16	73	533	74	523	3e-14	86.3
tr:G7YVP7_CLOSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.05	603	382	18	35	594	20	583	3e-14	87.0
tr:E1GTM8_9BACT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFN91985.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFN91985.1}; Flags: Fragment;	40.83	120	69	2	85	204	35	152	3e-14	82.0
rs:WP_029618624	DNA topoisomerase I [Rhizobium sp. MGL06].	24.58	659	365	33	55	630	27	636	3e-14	87.0
rs:WP_002472398	DNA topoisomerase I [Staphylococcus pettenkoferi].	23.19	565	380	18	90	629	67	602	3e-14	86.7
tr:A0A0D5U3L7_XANCI	SubName: Full=Topoisomerase IA {ECO:0000313|EMBL:AJZ44583.1};	27.60	250	155	9	409	639	6	248	3e-14	83.6
rs:WP_033162674	DNA topoisomerase I [Sharpea azabuensis].	23.00	661	408	26	3	629	4	597	3e-14	86.7
rs:WP_011057718	DNA topoisomerase I [Thermosynechococcus elongatus].	22.91	611	389	18	3	572	4	573	3e-14	86.7
rs:WP_005713869	DNA topoisomerase I [Lactobacillus rhamnosus].	23.88	578	364	19	90	629	68	607	3e-14	86.7
rs:WP_045776269	DNA topoisomerase I [Elstera litoralis].	22.71	700	401	27	1	630	1	630	3e-14	87.0
rs:WP_027066041	DNA topoisomerase I [Maribacter sp. Hel_I_7].	25.42	531	328	17	3	521	5	479	3e-14	86.7
rs:WP_005002702	DNA topoisomerase I [Nitrococcus mobilis].	22.26	575	353	18	3	538	5	524	3e-14	86.7
rs:WP_035448310	DNA topoisomerase I [Lactobacillus animalis].	24.06	586	349	22	103	642	97	632	3e-14	86.7
tr:T0SFG4_LACFE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.65	226	133	7	189	396	3	220	3e-14	82.8
rs:WP_006453789	DNA topoisomerase I [Synechococcus sp. PCC 7335].	23.45	499	303	12	77	530	67	531	3e-14	86.7
rs:WP_026317155	DNA topoisomerase I [Ahrensia kielensis].	23.19	720	426	27	1	655	1	658	3e-14	86.7
rs:XP_009355843	PREDICTED: DNA topoisomerase 3-alpha [Pyrus x bretschneideri].	23.27	636	393	23	3	585	11	604	3e-14	87.0
tr:K8BJP2_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	23.63	474	294	18	193	633	1	439	3e-14	86.7
tr:A0A0B8PEW1_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.47	154	99	3	243	391	6	159	3e-14	83.2
rs:WP_002336210	hypothetical protein, partial [Enterococcus faecium].	38.24	136	77	4	49	179	1	134	3e-14	81.3
sp:TOP1_SYNE7	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	23.22	633	369	21	2	577	3	575	3e-14	86.7
rs:WP_004636185	DNA topoisomerase I [Dolosigranulum pigrum].	24.05	582	367	24	90	635	68	610	3e-14	86.7
tr:W7VEV5_STRTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.54	559	362	21	103	630	108	626	3e-14	86.7
rs:WP_012305122	DNA topoisomerase I [Leuconostoc citreum].	23.04	560	364	20	88	616	84	607	3e-14	86.7
rs:WP_016709380	topoisomerase I [Pseudoalteromonas haloplanktis].	22.66	631	386	25	52	631	62	641	3e-14	86.7
tr:A0A023DYM8_9RICK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.05	499	304	18	75	533	52	520	3e-14	86.7
rs:WP_006924417	DNA topoisomerase I [Bartonella washoensis].	23.44	691	409	30	1	629	1	633	3e-14	86.7
tr:V8LW74_STRTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.54	559	362	21	103	630	108	626	3e-14	86.7
rs:WP_007227656	topoisomerase I [marine gamma proteobacterium HTCC2148].	23.98	588	385	20	74	633	92	645	4e-14	86.7
rs:WP_026804216	DNA topoisomerase I [Arcobacter sp. AF1581].	24.32	658	394	24	3	617	4	600	4e-14	86.7
rs:WP_013237965	MULTISPECIES: DNA topoisomerase I [Clostridium].	23.44	657	389	24	2	616	4	588	4e-14	86.7
rs:WP_011320483	DNA topoisomerase I [Anabaena variabilis].	25.00	588	360	21	79	622	59	609	4e-14	86.7
rs:WP_009514124	DNA topoisomerase I [Acinetobacter sp. WC-323].	23.18	578	359	18	90	629	117	647	4e-14	86.7
rs:WP_006689031	DNA topoisomerase I [Ureaplasma parvum].	22.22	648	404	23	32	629	19	616	4e-14	86.3
rs:WP_010420670	DNA topoisomerase I [Anaerophaga thermohalophila].	25.00	544	314	21	3	520	12	487	4e-14	86.7
rs:WP_018946671	DNA topoisomerase I [Thioalkalivibrio sp. AKL17].	22.45	579	339	17	3	534	5	520	4e-14	86.7
rs:WP_042642291	DNA topoisomerase I [Aeromonas eucrenophila].	23.43	606	367	22	75	633	82	637	4e-14	86.7
rs:WP_012797070	DNA topoisomerase I [Capnocytophaga ochracea].	24.49	535	326	16	3	521	5	477	4e-14	86.7
rs:WP_036173528	DNA topoisomerase I [Maribius sp. MOLA 401].	22.85	582	347	19	1	534	1	528	4e-14	86.7
tr:D2PW45_KRIFD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.80	658	389	24	2	591	21	627	4e-14	86.7
tr:B0NRM5_BACSE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.72	624	374	24	3	596	28	579	4e-14	86.7
rs:WP_045224643	DNA topoisomerase I [Methylococcaceae bacterium 73a].	23.48	511	318	15	70	534	37	520	4e-14	86.7
rs:WP_036898276	DNA topoisomerase I [Prevotella sp. S7 MS 2].	22.72	603	369	19	3	580	5	535	4e-14	86.7
rs:WP_021752225	DNA topoisomerase I [Gemella bergeri].	26.14	570	329	23	103	629	81	601	4e-14	86.3
rs:WP_021700517	DNA topoisomerase I [Pseudomonas alcaligenes].	22.74	475	301	12	186	629	195	634	4e-14	86.7
rs:WP_043561693	DNA topoisomerase I [Saccharibacter sp. AM169].	23.11	649	387	26	55	631	28	636	4e-14	86.7
rs:WP_006530388	DNA topoisomerase I [Gloeocapsa sp. PCC 73106].	23.72	527	330	16	88	574	82	576	4e-14	86.7
rs:WP_013214669	DNA topoisomerase I [Hyphomicrobium denitrificans].	26.12	559	328	23	55	557	27	556	4e-14	86.7
rs:WP_038281690	DNA topoisomerase I [[Clostridium] celerecrescens].	23.89	561	357	19	90	616	67	591	4e-14	86.3
rs:WP_012334082	DNA topoisomerase I [Methylobacterium sp. 4-46].	23.61	682	417	27	1	629	1	631	4e-14	86.7
rs:WP_018082189	DNA topoisomerase I [Asticcacaulis benevestitus].	23.17	600	374	21	1	565	1	548	4e-14	86.7
tr:D7IZD4_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.53	544	335	19	3	526	15	497	4e-14	86.7
rs:WP_031413665	DNA topoisomerase I [Brevibacillus laterosporus].	23.27	563	375	21	103	636	80	614	4e-14	86.3
rs:WP_019130607	DNA topoisomerase I [Bacteroidales bacterium ph8].	22.41	540	344	17	3	526	5	485	4e-14	86.7
rs:WP_040176843	DNA topoisomerase I [Leuconostoc citreum].	23.04	560	364	20	88	616	84	607	4e-14	86.3
rs:WP_036060875	DNA topoisomerase I [Leuconostoc citreum].	23.04	560	364	20	88	616	81	604	4e-14	86.3
rs:WP_008440553	DNA topoisomerase I, archaeal [Thaumarchaeota archaeon SCGC AB-539-E09].	24.64	418	273	14	3	394	6	407	4e-14	85.9
rs:WP_009815756	DNA topoisomerase I [Roseovarius sp. 217].	21.64	707	419	26	1	630	1	649	4e-14	86.7
rs:WP_046444718	DNA topoisomerase I [Catabacter hongkongensis].	23.51	587	345	22	76	614	48	578	4e-14	86.3
rs:WP_019138070	DNA topoisomerase I [Peptoniphilus timonensis].	23.43	559	359	18	90	616	67	588	4e-14	86.3
rs:WP_013184437	topoisomerase I [Xenorhabdus nematophila].	23.08	533	315	20	187	673	190	673	4e-14	86.7
rs:WP_007572797	DNA topoisomerase I [Prevotella multisaccharivorax].	22.85	604	386	18	3	593	5	541	4e-14	86.3
rs:WP_030440735	DNA topoisomerase I [Actinoplanes subtropicus].	23.27	709	401	28	2	642	9	642	4e-14	86.7
tr:A0A0D1YDN6_9EURO	SubName: Full=Strain CBS 89968 unplaced genomic scaffold supercont1.6, whole genome shotgun sequence {ECO:0000313|EMBL:KIW13136.1};	23.81	483	299	17	150	593	165	617	4e-14	86.3
rs:WP_009418982	DNA topoisomerase I [Capnocytophaga sp. oral taxon 380].	24.49	535	326	16	3	521	5	477	4e-14	86.7
rs:WP_045372432	DNA topoisomerase I [Jejuia pallidilutea].	25.05	535	323	20	3	521	5	477	4e-14	86.7
rs:WP_023364833	hypothetical protein [Spiribacter sp. UAH-SP71].	22.39	585	355	17	3	538	5	539	4e-14	86.3
rs:WP_010702397	DNA topoisomerase I [Bartonella bovis].	23.91	690	407	32	1	629	1	633	4e-14	86.7
rs:WP_005942398	MULTISPECIES: DNA topoisomerase I [Bacteroides].	23.71	599	364	21	3	578	5	533	4e-14	86.3
tr:Q5CBE3_9THEM	RecName: Full=Reverse gyrase {ECO:0000256|HAMAP-Rule:MF_01125, ECO:0000256|RuleBase:RU004026};	23.38	479	268	15	81	533	640	1045	4e-14	86.7
rs:WP_004800148	DNA topoisomerase I [Acinetobacter sp. CIP 102637].	22.97	579	359	19	90	629	117	647	4e-14	86.7
rs:WP_041429665	DNA topoisomerase I, partial [Synechococcus sp. PCC 7502].	23.23	607	380	17	3	566	4	567	4e-14	86.3
rs:WP_033573047	DNA topoisomerase I [Lactobacillus rhamnosus].	23.44	576	369	18	90	629	68	607	4e-14	86.3
rs:WP_005688022	DNA topoisomerase I [Lactobacillus rhamnosus].	23.44	576	369	18	90	629	68	607	4e-14	86.3
rs:WP_014404407	DNA topoisomerase I [Frateuria aurantia].	22.88	577	353	19	3	538	5	530	4e-14	86.3
rs:WP_009022464	topoisomerase I [gamma proteobacterium NOR5-3].	22.87	599	377	20	72	629	86	640	4e-14	86.7
rs:WP_015691241	DNA topoisomerase I [Saprospira grandis].	25.46	436	280	13	74	481	54	472	4e-14	86.7
tr:A0A060QAM0_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.11	649	387	26	55	631	30	638	4e-14	86.7
rs:WP_046474260	DNA topoisomerase I [marine gamma proteobacterium ASP10-03a].	23.65	592	362	19	83	629	100	646	4e-14	86.7
rs:WP_005773509	DNA topoisomerase I [Bartonella elizabethae].	22.96	697	405	27	1	629	1	633	4e-14	86.3
rs:WP_043831062	DNA topoisomerase I [Roseomonas aerilata].	22.40	558	356	17	103	610	81	611	4e-14	86.7
rs:WP_024061638	DNA topoisomerase [Veillonella dispar].	22.81	570	366	20	95	629	142	672	4e-14	86.3
rs:WP_002349050	hypothetical protein, partial [Enterococcus faecium].	26.67	210	142	3	413	610	12	221	4e-14	82.8
rs:WP_009641356	DNA topoisomerase I [Capnocytophaga sp. CM59].	25.61	531	325	18	3	521	5	477	4e-14	86.3
rs:WP_032850977	DNA topoisomerase I [Bacteroides sp. D22].	22.91	598	374	19	3	580	5	535	4e-14	86.3
rs:WP_045680085	DNA topoisomerase I [Roseovarius sp. BRH_c41].	21.67	706	418	26	1	629	1	648	4e-14	86.7
rs:WP_015147956	DNA topoisomerase I [Oscillatoria acuminata].	23.94	614	355	22	3	560	4	561	4e-14	86.3
rs:WP_018259862	DNA topoisomerase I [Methylobacterium sp. WSM2598].	23.61	682	417	27	1	629	1	631	4e-14	86.7
rs:WP_018578499	DNA topoisomerase I [Legionella shakespearei].	24.17	629	385	27	55	630	29	618	4e-14	86.3
rs:WP_042958068	DNA topoisomerase, partial [Enterococcus faecium].	28.84	267	155	8	158	399	18	274	4e-14	83.2
rs:WP_013670801	DNA topoisomerase I [Prevotella denticola].	23.11	610	363	21	3	580	5	540	4e-14	86.3
rs:WP_029906193	DNA topoisomerase I [Prevotella sp. 10(H)].	24.77	537	327	17	3	521	5	482	4e-14	86.3
rs:WP_025977129	DNA topoisomerase I [Brevundimonas naejangsanensis].	22.36	559	337	18	1	520	1	501	4e-14	86.3
tr:D0TKZ0_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.53	544	335	20	3	526	15	497	5e-14	86.3
rs:WP_004317201	MULTISPECIES: DNA topoisomerase I [Bacteroides].	23.53	544	335	20	3	526	5	487	5e-14	86.3
rs:WP_039150118	DNA topoisomerase I [Leisingera sp. ANG-DT].	22.71	700	414	29	1	630	1	643	5e-14	86.3
rs:XP_001526340	conserved hypothetical protein [Lodderomyces elongisporus NRRL YB-4239].	22.10	629	387	21	3	574	4	586	5e-14	85.9
rs:WP_019589952	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	22.93	567	351	18	3	534	5	520	5e-14	86.3
rs:WP_004353642	topoisomerase [Prevotella denticola].	32.95	176	100	5	4	168	5	173	5e-14	81.6
rs:WP_015425427	DNA topoisomerase I [Candidatus Cloacimonas acidaminovorans].	25.67	600	360	23	83	639	60	616	5e-14	86.3
rs:WP_033849501	DNA topoisomerase I [Acinetobacter baumannii].	22.54	590	380	17	74	629	100	646	5e-14	86.3
rs:WP_041483233	hypothetical protein, partial [Thioalkalimicrobium aerophilum].	22.70	564	352	18	55	591	27	533	5e-14	85.5
rs:WP_045479482	DNA topoisomerase I [Bacillus sp. TS-2].	23.43	559	361	20	105	630	82	606	5e-14	86.3
tr:A0A0A1GXE3_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.56	241	153	6	261	488	18	247	5e-14	83.2
rs:WP_015783361	DNA topoisomerase I [Cyanothece sp. PCC 8802].	22.90	607	370	18	3	560	4	561	5e-14	86.3
rs:WP_034530828	DNA topoisomerase I [Lactobacillus kunkeei].	23.34	557	362	22	103	629	95	616	5e-14	86.3
rs:WP_046206438	DNA topoisomerase I [Streptococcus thermophilus].	22.72	559	361	21	103	630	108	626	5e-14	86.3
rs:WP_028906033	DNA topoisomerase I [Prevotella intermedia].	22.43	602	377	18	3	580	5	540	5e-14	86.3
rs:WP_041152313	DNA topoisomerase I [Lactobacillus kunkeei].	23.61	559	358	22	103	629	95	616	5e-14	86.3
rs:WP_008552945	DNA topoisomerase I [Pseudovibrio sp. JE062].	23.40	577	339	18	1	534	1	517	5e-14	86.3
rs:WP_034363738	DNA topoisomerase I [Helicobacter sp. MIT 01-6451].	24.18	488	301	14	163	614	138	592	5e-14	86.3
rs:WP_013908188	DNA topoisomerase I [Thermodesulfatator indicus].	24.87	587	361	21	100	652	77	617	5e-14	86.3
tr:A0A015JH69_9GLOM	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EXX54264.1};	22.94	619	397	23	3	577	7	589	5e-14	86.3
rs:WP_008960772	DNA topoisomerase I [Bradyrhizobium sp. STM 3809].	24.29	601	374	22	84	630	10	583	5e-14	86.3
rs:WP_007162385	topoisomerase I [Pseudomonas psychrotolerans].	23.95	476	302	16	186	633	194	637	5e-14	86.3
tr:A5AWM5_VITVI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.46	635	399	28	32	610	409	1012	5e-14	86.3
rs:WP_012988731	topoisomerase I [Xenorhabdus bovienii].	23.71	485	292	17	187	633	188	632	5e-14	86.3
tr:C5RBD7_WEIPA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.43	670	399	23	3	629	36	634	5e-14	85.9
tr:A0A0E1SR17_HAEIF	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EDK12148.1};	41.84	98	57	0	486	583	8	105	5e-14	80.9
tr:D4RFQ4_ENTFC	SubName: Full=Topoisomerase {ECO:0000313|EMBL:EFF27246.1};	29.26	229	145	8	460	673	75	301	5e-14	84.0
rs:WP_038197567	DNA topoisomerase I [Xenorhabdus bovienii].	23.92	485	291	17	187	633	188	632	5e-14	86.3
rs:WP_016542433	DNA topoisomerase I [Acinetobacter gyllenbergii].	22.97	579	359	19	90	629	117	647	5e-14	86.3
tr:E4XGA0_OIKDI	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	21.11	682	432	27	27	653	44	674	5e-14	86.3
rs:WP_025643987	MULTISPECIES: DNA topoisomerase I [Psychrobacter].	24.73	651	386	27	77	673	136	736	5e-14	86.3
rs:WP_023048857	hypothetical protein, partial [Pseudomonas putida].	30.00	170	108	4	1	167	12	173	5e-14	81.6
tr:X0R4V8_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.72	586	378	20	77	629	104	653	5e-14	86.3
rs:WP_044324931	DNA topoisomerase III, partial [Pseudomonas amygdali].	28.76	233	147	6	1	223	1	224	5e-14	83.2
tr:S5VWG9_ENTFC	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AGS75352.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AGS75352.1};	29.26	229	145	8	460	673	66	292	5e-14	83.6
rs:WP_028376425	DNA topoisomerase I [Leeuwenhoekiella sp. Hel_I_48].	24.01	654	397	21	3	618	5	596	5e-14	86.3
rs:WP_024352735	DNA topoisomerase I [Brevundimonas naejangsanensis].	22.36	559	337	18	1	520	1	501	5e-14	86.3
rs:WP_004047861	DNA topoisomerase I [Lactobacillus murinus].	24.01	583	353	22	103	642	97	632	5e-14	85.9
rs:WP_034598654	DNA topoisomerase I [Desulfosporosinus sp. HMP52].	23.18	591	373	22	88	634	62	615	5e-14	85.9
rs:XP_009560480	PREDICTED: DNA topoisomerase 3-alpha [Cuculus canorus].	24.64	483	297	18	188	634	241	692	5e-14	86.3
rs:WP_012242292	topoisomerase I [Acholeplasma laidlawii].	24.74	586	353	25	77	629	57	587	5e-14	85.9
tr:E1KUI6_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.31	605	368	21	3	580	19	554	5e-14	86.3
rs:WP_013309879	DNA topoisomerase I [Paenibacillus polymyxa].	22.97	566	374	20	103	636	80	615	5e-14	85.9
rs:WP_025021506	hypothetical protein [Lactobacillus equi].	23.42	491	289	17	3	431	7	472	5e-14	85.5
tr:K9SQT0_9SYNE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.23	607	380	17	3	566	4	567	5e-14	86.3
tr:A7LW71_BACO1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.71	544	334	20	3	526	15	497	5e-14	86.3
rs:XP_002985109	hypothetical protein SELMODRAFT_121488 [Selaginella moellendorffii].	22.08	634	399	23	3	585	6	595	5e-14	86.3
rs:XP_009174223	hypothetical protein T265_09785 [Opisthorchis viverrini].	22.25	409	276	12	238	629	115	498	5e-14	86.3
rs:WP_026950130	DNA topoisomerase I [Algoriphagus mannitolivorans].	28.98	352	217	10	55	392	29	361	5e-14	85.9
tr:A0A024FAL9_UREPR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.22	648	404	23	32	629	23	620	5e-14	85.9
rs:WP_022564615	DNA topoisomerase I [Candidatus Pantoea carbekii].	22.13	574	383	18	90	633	93	632	5e-14	86.3
rs:WP_034844101	DNA topoisomerase I, partial [Inquilinus limosus].	23.29	687	415	28	3	630	6	639	5e-14	86.3
rs:WP_016144255	DNA topoisomerase I [Acinetobacter pittii].	22.65	574	367	17	90	629	116	646	5e-14	86.3
rs:WP_044126130	hypothetical protein [Vibrio cholerae].	23.79	559	351	18	100	620	72	593	5e-14	86.3
rs:WP_042832025	DNA topoisomerase III, partial [Xanthomonas citri].	29.17	216	133	7	437	639	25	233	5e-14	82.8
rs:WP_038224847	DNA topoisomerase I [Xenorhabdus bovienii].	23.92	485	291	17	187	633	188	632	5e-14	86.3
rs:WP_005715619	DNA topoisomerase I [Lactobacillus rhamnosus].	23.74	577	366	18	90	629	68	607	5e-14	85.9
rs:WP_022323727	DNA topoisomerase [Alistipes sp. CAG:435].	24.84	483	288	16	76	527	53	491	5e-14	85.9
rs:WP_004762171	DNA topoisomerase I [Acinetobacter sp. CIP 102129].	23.18	578	359	18	90	629	117	647	5e-14	86.3
rs:WP_021758054	DNA topoisomerase I [Leifsonia aquatica].	23.73	590	335	21	2	530	6	541	5e-14	86.3
rs:WP_024341083	DNA topoisomerase I [Bradyrhizobium japonicum].	22.90	703	432	25	1	647	1	649	5e-14	86.3
rs:WP_014342408	DNA topoisomerase I [Treponema pallidum].	23.36	458	298	12	186	618	175	604	5e-14	85.9
rs:WP_034821487	DNA topoisomerase I [Enterobacter cancerogenus].	23.17	479	302	15	187	633	190	634	5e-14	86.3
rs:WP_025684918	DNA topoisomerase I [Paenibacillus sp. 1-49].	22.38	563	381	19	103	636	80	615	5e-14	85.9
rs:WP_019152081	DNA topoisomerase I [Alistipes senegalensis].	24.63	467	299	16	77	525	54	485	5e-14	85.9
rs:WP_027773285	DNA topoisomerase I [Streptomyces sp. CNQ329].	23.53	595	333	20	2	530	9	547	6e-14	86.3
rs:WP_032012359	DNA topoisomerase I [Acinetobacter baumannii].	22.65	574	367	17	90	629	116	646	6e-14	86.3
rs:WP_046811441	DNA topoisomerase I [Acinetobacter pittii].	22.65	574	367	17	90	629	116	646	6e-14	86.3
rs:WP_027003233	DNA topoisomerase I [Flexibacter roseolus].	24.38	320	226	5	77	392	54	361	6e-14	85.9
rs:WP_038208563	DNA topoisomerase I [Xenorhabdus bovienii].	23.92	485	291	17	187	633	188	632	6e-14	86.3
tr:I8YT13_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.65	627	391	22	3	604	37	594	6e-14	85.9
rs:WP_002115027	MULTISPECIES: topoisomerase I [Acinetobacter calcoaceticus/baumannii complex].	22.65	574	367	17	90	629	116	646	6e-14	86.3
rs:WP_031947281	DNA topoisomerase I [Acinetobacter baumannii].	22.65	574	367	17	90	629	116	646	6e-14	86.3
rs:WP_040556296	DNA topoisomerase I [Prevotella disiens].	23.31	605	368	21	3	580	24	559	6e-14	85.9
rs:WP_038526951	DNA topoisomerase I [Formosa agariphila].	24.86	535	324	20	3	521	5	477	6e-14	85.9
rs:WP_005066066	MULTISPECIES: DNA topoisomerase I [Acinetobacter calcoaceticus/baumannii complex].	22.65	574	367	17	90	629	116	646	6e-14	86.3
tr:A0A0E0GH85_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA03G04610.3};	21.56	733	445	31	3	653	14	698	6e-14	86.3
rs:WP_015207494	DNA topoisomerase I [Cylindrospermum stagnale].	25.72	587	351	23	79	618	59	607	6e-14	85.9
rs:WP_044626838	DNA topoisomerase I [Tamlana nanhaiensis].	23.88	670	384	25	3	621	5	599	6e-14	85.9
rs:WP_029667746	hypothetical protein, partial [Calescamantes bacterium JGI 0000106-I17].	22.75	668	420	23	1	629	1	611	6e-14	85.5
rs:WP_012491591	MULTISPECIES: DNA topoisomerase I [Lactobacillus casei group].	23.91	573	370	18	90	629	68	607	6e-14	85.9
rs:WP_017385701	MULTISPECIES: topoisomerase I [Acinetobacter].	22.65	574	367	17	90	629	116	646	6e-14	85.9
rs:WP_017482015	topoisomerase I [Acinetobacter calcoaceticus].	22.65	574	367	17	90	629	116	646	6e-14	85.9
rs:WP_037048654	DNA topoisomerase I [Pseudomonas oleovorans].	22.98	483	298	13	186	633	194	637	6e-14	85.9
rs:WP_011021792	DNA topoisomerase [Methanosarcina acetivorans].	23.11	636	397	25	21	611	27	615	6e-14	85.9
tr:B9YAX6_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.65	668	401	26	3	629	6	605	6e-14	85.9
rs:WP_033752330	DNA topoisomerase I [Helicobacter pylori].	24.54	485	330	14	75	536	46	517	6e-14	85.9
rs:WP_005079182	MULTISPECIES: DNA topoisomerase I [Acinetobacter calcoaceticus/baumannii complex].	22.65	574	367	17	90	629	116	646	6e-14	85.9
tr:A0A086J4E5_9MICR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.72	640	413	20	3	602	4	595	6e-14	85.9
rs:WP_035825898	DNA topoisomerase I [Crocosphaera watsonii].	24.07	619	348	22	3	560	4	561	6e-14	85.9
rs:WP_017361524	topoisomerase I [Pseudomonas mendocina].	22.89	485	296	12	186	633	195	638	6e-14	85.9
rs:WP_029457032	DNA topoisomerase I [Desulfovibrio alcoholivorans].	24.45	642	392	26	76	669	53	649	6e-14	85.9
tr:A0A024GVE1_9STRA	SubName: Full=Albugo candida WGS project CAIX00000000 data, strain Ac Nc2, contig AcNc2_CONTIG_579_length_13152 {ECO:0000313|EMBL:CCI50571.1};	23.61	466	291	15	188	616	206	643	6e-14	85.9
rs:WP_029520244	DNA topoisomerase I [Persephonella sp. IF05-L8].	24.62	524	343	16	90	593	69	560	6e-14	85.5
tr:A0A090QZ46_9GAMM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL07513.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL07513.1};	34.92	126	82	0	456	581	6	131	6e-14	81.6
tr:T0E7D5_CLOSO	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EPZ59488.1};	34.91	169	83	6	467	631	9	154	6e-14	82.4
rs:XP_008378234	PREDICTED: uncharacterized protein LOC103441330 [Malus domestica].	23.70	519	323	21	64	536	362	853	6e-14	85.9
rs:WP_034291938	DNA topoisomerase I [Alysiella crassa].	21.83	678	423	23	70	679	37	675	6e-14	85.9
rs:WP_011609954	DNA topoisomerase I [Trichodesmium erythraeum].	23.44	627	364	23	3	571	4	572	6e-14	85.9
rs:WP_023988184	DNA topoisomerase I [Paenibacillus polymyxa].	22.97	566	374	20	103	636	80	615	6e-14	85.5
tr:A0A093F4L3_GAVST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.64	483	297	18	188	634	219	670	6e-14	85.9
rs:WP_040488363	DNA topoisomerase I, partial [Fodinicurvata sediminis].	22.45	695	413	30	1	630	1	634	6e-14	85.9
rs:XP_004843383	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Heterocephalus glaber].	22.01	668	395	23	3	585	5	631	6e-14	85.9
tr:T2JG30_CROWT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.07	619	348	22	3	560	4	561	6e-14	85.9
rs:WP_022857371	DNA topoisomerase I [Alloscardovia omnicolens].	24.45	589	343	20	2	538	6	544	6e-14	85.9
rs:WP_018043601	DNA topoisomerase I [Methylobacterium sp. 88A].	23.32	686	414	26	1	629	1	631	6e-14	85.9
rs:WP_011457582	DNA topoisomerase I [Chlamydophila felis].	22.41	772	431	32	3	670	5	712	6e-14	85.9
rs:WP_029936286	DNA topoisomerase I [Thiomicrospira pelophila].	22.53	617	387	19	3	596	4	552	6e-14	85.9
tr:R0M9K0_NOSB1	SubName: Full=DNA topoisomerase 3-alpha {ECO:0000313|EMBL:EOB14659.1};	22.66	609	389	20	3	577	4	564	6e-14	85.9
rs:WP_021853268	DNA topoisomerase [Prevotella sp. CAG:1058].	23.92	602	359	21	3	578	5	533	6e-14	85.9
tr:J3LKB1_ORYBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.90	642	387	28	3	585	13	605	7e-14	85.9
tr:M7U3M0_BOTF1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.51	553	355	21	3	520	6	525	7e-14	85.5
rs:WP_014079538	DNA topoisomerase I [Roseburia hominis].	22.52	453	304	12	187	616	161	589	7e-14	85.5
tr:F0WSH2_9STRA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.76	624	393	22	3	581	5	584	7e-14	85.9
rs:WP_004302491	DNA topoisomerase I [Bacteroides ovatus].	23.71	544	334	20	3	526	5	487	7e-14	85.9
rs:WP_025819229	DNA topoisomerase I [Bacteroides salyersiae].	22.65	627	391	22	3	604	5	562	7e-14	85.9
rs:WP_044059489	DNA topoisomerase III, partial [Escherichia coli].	35.04	117	66	4	1	113	1	111	7e-14	80.5
rs:WP_016284604	DNA topoisomerase III [Lachnospiraceae bacterium A4].	37.27	110	61	3	1	107	1	105	7e-14	79.7
rs:WP_012200735	DNA topoisomerase I [Lachnoclostridium phytofermentans].	21.86	558	370	14	90	616	67	589	7e-14	85.5
rs:WP_015410922	DNA topoisomerase I [Methanosarcina mazei].	22.96	636	398	25	21	611	27	615	7e-14	85.9
rs:WP_025329888	DNA topoisomerase I [Snodgrassella alvi].	21.84	673	418	25	3	630	5	614	7e-14	85.9
rs:WP_025761525	DNA topoisomerase I [Dyadobacter tibetensis].	22.60	531	338	16	3	520	5	475	7e-14	85.9
rs:WP_020863281	DNA topoisomerase III [Candidatus Caldiarchaeum subterraneum].	25.39	323	209	10	3	314	16	317	7e-14	85.5
rs:WP_041981348	DNA topoisomerase I [Xenorhabdus nematophila].	23.08	533	315	20	187	673	190	673	7e-14	85.9
rs:WP_028542727	DNA topoisomerase I [Paenibacillus sp. UNCCL52].	22.97	566	374	20	103	636	80	615	7e-14	85.5
rs:WP_041436909	DNA topoisomerase I [Thermomicrobium roseum].	21.40	598	382	21	85	629	55	617	7e-14	85.5
rs:WP_016657559	DNA topoisomerase I [Acinetobacter rudis].	22.43	477	296	13	187	629	210	646	7e-14	85.9
rs:WP_047016523	DNA topoisomerase I [Streptomyces sp. CNQ-509].	23.17	682	376	25	2	591	9	634	7e-14	85.9
rs:WP_042783047	hypothetical protein, partial [Vibrio parahaemolyticus].	32.23	121	74	3	1	118	1	116	7e-14	80.1
rs:WP_042096028	DNA topoisomerase III, partial [Escherichia coli].	35.04	117	66	4	1	113	1	111	7e-14	80.5
rs:WP_007305008	DNA topoisomerase I [Crocosphaera watsonii].	24.07	619	348	22	3	560	4	561	7e-14	85.9
rs:WP_022308153	DNA topoisomerase [Alistipes sp. CAG:268].	23.25	542	338	19	3	526	5	486	7e-14	85.5
tr:D7JXC8_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.71	544	334	20	3	526	15	497	7e-14	85.9
rs:WP_037136048	DNA topoisomerase I [Rhizobium leucaenae].	22.21	662	406	26	38	630	16	637	7e-14	85.9
rs:WP_027310435	DNA topoisomerase I [Bacteroidetes bacterium SCGC AAA027-N21].	24.62	532	329	19	3	521	5	477	7e-14	85.9
rs:WP_009161146	DNA topoisomerase, partial [Prevotella saccharolytica].	25.90	251	167	8	258	497	61	303	7e-14	82.8
rs:WP_017292861	DNA topoisomerase I [Geminocystis herdmanii].	24.28	626	366	24	3	574	4	575	7e-14	85.9
tr:A0A0B8QHJ9_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.45	448	274	15	57	481	83	493	7e-14	85.1
rs:XP_006649448	PREDICTED: DNA topoisomerase 3-alpha-like [Oryza brachyantha].	22.90	642	387	28	3	585	13	605	7e-14	85.9
rs:WP_039865010	DNA topoisomerase I [Holdemania filiformis].	23.65	668	401	26	3	629	4	603	7e-14	85.5
rs:XP_005714096	unnamed protein product [Chondrus crispus].	21.12	644	393	19	3	577	6	603	7e-14	85.9
rs:WP_010557475	topoisomerase I [Pseudoalteromonas marina].	23.40	611	388	22	60	631	72	641	7e-14	85.9
rs:WP_006792157	topoisomerase I [Alteromonadales bacterium TW-7].	23.40	611	388	22	60	631	72	641	7e-14	85.9
tr:K7HB22_CAEJA	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:CJA21342c};	22.37	617	392	19	32	614	491	1054	7e-14	86.3
rs:WP_046412494	DNA topoisomerase I [Bacteroides sp. N54.MGS-20].	23.32	536	343	16	3	526	5	484	7e-14	85.5
tr:A0A091G737_9AVES	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.64	483	297	18	188	634	221	672	7e-14	85.9
rs:WP_018108870	DNA topoisomerase I [Bacteroides propionicifaciens].	24.37	554	348	19	77	602	54	564	7e-14	85.5
rs:WP_036068320	DNA topoisomerase I [Leuconostoc pseudomesenteroides].	22.38	581	365	19	90	629	83	618	7e-14	85.5
rs:WP_046510235	DNA topoisomerase III, partial [Kiloniella sp. P1-1].	32.23	121	74	3	1	118	1	116	7e-14	80.1
rs:WP_011032137	DNA topoisomerase [Methanosarcina mazei].	22.94	632	403	24	21	611	27	615	7e-14	85.5
rs:WP_038646692	DNA topoisomerase I [Pantoea rwandensis].	22.87	481	301	16	187	633	190	634	7e-14	85.9
rs:WP_021935813	MULTISPECIES: DNA topoisomerase [Bacteroides].	22.65	627	391	22	3	604	5	562	7e-14	85.5
rs:WP_004913035	DNA topoisomerase I [Leuconostoc pseudomesenteroides].	22.38	581	365	19	90	629	88	623	7e-14	85.5
rs:WP_039791863	DNA topoisomerase III, partial [Haemophilus sputorum].	28.94	273	175	7	61	317	7	276	7e-14	82.8
rs:WP_026016696	DNA topoisomerase I [Catenovulum agarivorans].	22.30	601	378	20	76	633	86	640	7e-14	85.9
rs:WP_004920177	MULTISPECIES: topoisomerase I [Acinetobacter].	23.33	480	288	14	187	629	213	649	7e-14	85.9
tr:U4QTL0_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.03	673	414	29	3	631	52	664	7e-14	85.5
rs:WP_016371159	DNA topoisomerase I [Lactobacillus paracasei].	23.91	573	370	18	90	629	68	607	7e-14	85.5
rs:WP_020444080	topoisomerase I [Psychrobacter sp. G].	23.88	645	399	24	77	673	108	708	7e-14	85.9
gpu:CP009511_1054	DNA topoisomerase I [Methanosarcina mazei SarPi]	22.96	636	398	25	21	611	27	615	7e-14	85.5
rs:WP_040572020	DNA topoisomerase I [Shewanella benthica].	22.57	607	369	20	74	631	88	642	7e-14	85.9
rs:WP_045814401	DNA topoisomerase I [Pantoea sp. SM3].	23.17	479	302	15	187	633	190	634	7e-14	85.5
tr:A0A0C9MP41_9FUNG	SubName: Full=DNA, scaffold: scf_mam1_v10081, strain NBRC 6742, whole genome shotgun sequence {ECO:0000313|EMBL:GAN05052.1};	22.62	367	235	9	188	537	234	568	8e-14	85.1
rs:WP_004323870	MULTISPECIES: DNA topoisomerase I [Bacteroides].	23.53	544	335	19	3	526	5	487	8e-14	85.5
rs:WP_029505861	DNA topoisomerase I [Lachnospiraceae bacterium AC2012].	22.56	554	372	16	90	616	67	590	8e-14	85.5
rs:WP_009340934	DNA topoisomerase I [Afipia sp. 1NLS2].	22.91	694	410	32	1	630	1	633	8e-14	85.9
rs:XP_009079665	PREDICTED: DNA topoisomerase 3-alpha [Acanthisitta chloris].	24.67	458	287	16	188	616	241	669	8e-14	85.9
rs:WP_026472027	DNA topoisomerase I [Alkanindiges illinoisensis].	25.00	488	296	18	74	533	118	563	8e-14	85.9
rs:WP_021802116	DNA topoisomerase I [Clostridium intestinale].	24.34	604	344	22	103	630	80	646	8e-14	85.5
tr:V1SZV9_SALET	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESG09311.1};	35.04	117	66	4	1	113	1	111	8e-14	80.1
rs:XP_005949422	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X4 [Haplochromis burtoni].	22.32	587	360	20	3	539	5	545	8e-14	85.1
rs:WP_010772513	DNA topoisomerase 1 [Enterococcus caccae].	24.64	560	355	20	103	629	81	606	8e-14	85.5
rs:XP_009622050	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Nicotiana tomentosiformis].	22.96	636	395	24	3	585	14	607	8e-14	85.5
rs:WP_023491655	DNA topoisomerase 1 [Serratia sp. DD3].	22.39	679	363	27	75	673	79	673	8e-14	85.5
tr:F6H2W0_VITVI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.15	635	401	27	32	610	110	713	8e-14	85.5
rs:WP_008862920	DNA topoisomerase I [Barnesiella intestinihominis].	23.32	536	343	16	3	526	5	484	8e-14	85.5
tr:L8JM96_9BACT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ELR68512.1};	29.86	211	132	7	298	496	2	208	8e-14	81.6
rs:WP_046288885	DNA topoisomerase I [Blochmannia endosymbiont of Polyrhachis (Hedomyrma) turneri].	23.98	588	363	20	57	614	76	609	8e-14	85.5
rs:XP_010001864	PREDICTED: DNA topoisomerase 3-alpha [Chaetura pelagica].	23.98	488	294	17	188	634	241	692	8e-14	85.9
tr:A0A0E0NQ39_ORYRU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ORUFI03G04550.3};	22.00	641	394	26	3	585	13	605	8e-14	85.5
rs:XP_006688044	hypothetical protein CANTEDRAFT_108430 [Candida tenuis ATCC 10573].	23.38	616	378	19	3	564	4	579	8e-14	85.1
gpu:LN847056_15	DNA topoisomerase 1 [Chlamydia pneumoniae]	23.84	583	332	20	3	534	5	526	8e-14	85.5
tr:B9L0B0_THERP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.40	598	382	21	85	629	91	653	8e-14	85.5
rs:WP_012460546	DNA topoisomerase I [Treponema pallidum].	23.36	458	298	12	186	618	175	604	8e-14	85.5
rs:WP_023830660	DNA topoisomerase I [Mesorhizobium sp. L103C119B0].	22.40	701	405	26	1	630	1	633	8e-14	85.5
rs:XP_009622049	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Nicotiana tomentosiformis].	22.96	636	395	24	3	585	14	607	8e-14	85.5
rs:WP_008131540	topoisomerase I [Pseudoalteromonas sp. BSi20480].	23.40	611	388	22	60	631	72	641	8e-14	85.5
rs:XP_009946177	PREDICTED: DNA topoisomerase 3-alpha, partial [Leptosomus discolor].	24.43	483	298	18	188	634	179	630	8e-14	85.9
rs:WP_033474582	DNA topoisomerase I [Bordetella bronchiseptica].	22.65	574	363	19	90	631	65	589	8e-14	85.5
rs:WP_035922521	DNA topoisomerase I, partial [Kordiimonas gwangyangensis].	21.20	698	414	24	1	630	1	630	8e-14	85.5
tr:K1RMM9_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central domain protein {ECO:0000313|EMBL:EKC44784.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EKC44784.1}; Flags: Fragment;	30.24	248	160	7	262	502	18	259	8e-14	82.4
rs:WP_014186866	DNA topoisomerase I [Desulfosporosinus orientis].	23.86	591	369	24	88	634	62	615	8e-14	85.5
rs:WP_027952528	DNA topoisomerase I [Hallella seregens].	24.22	545	329	19	3	526	5	486	8e-14	85.5
rs:WP_005811721	DNA topoisomerase I [Bacteroides fragilis].	24.04	628	371	27	3	604	5	552	8e-14	85.5
rs:WP_032852404	DNA topoisomerase I [Bacteroides sp. 3_1_23].	23.71	544	334	20	3	526	5	487	8e-14	85.5
rs:WP_026798579	MULTISPECIES: DNA topoisomerase I [Planktothrix].	22.09	652	393	18	3	587	4	607	8e-14	85.5
tr:K7HB20_CAEJA	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:CJA21342a};	22.37	617	392	19	32	614	491	1054	8e-14	86.3
tr:K7HB21_CAEJA	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:CJA21342b};	22.37	617	392	19	32	614	491	1054	8e-14	86.3
rs:WP_026668681	DNA topoisomerase I [Butyrivibrio sp. AE3009].	24.38	566	347	20	90	616	62	585	8e-14	85.5
rs:WP_026753684	DNA topoisomerase I [Sediminibacter sp. Hel_I_10].	24.40	500	318	15	154	621	128	599	8e-14	85.5
rs:WP_019903957	DNA topoisomerase I [Methylobacterium sp. 77].	23.19	690	410	28	1	629	1	631	8e-14	85.5
rs:WP_032107141	DNA topoisomerase III, partial [Escherichia coli].	35.04	117	66	4	1	113	1	111	8e-14	80.1
rs:WP_005955940	DNA topoisomerase I [Peptoniphilus harei].	23.27	593	378	22	90	644	67	620	8e-14	85.5
tr:E6S4J0_HELPF	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	23.87	486	332	14	75	536	46	517	8e-14	84.7
rs:XP_010017397	PREDICTED: DNA topoisomerase 3-alpha [Nestor notabilis].	23.44	482	303	16	188	634	229	679	8e-14	85.9
tr:A0A091NCS3_9PASS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.67	458	287	16	188	616	221	649	8e-14	85.5
rs:WP_010764920	DNA topoisomerase 1 [Enterococcus moraviensis].	25.00	560	353	21	103	629	81	606	8e-14	85.5
rs:WP_005878152	DNA topoisomerase I [Enterococcus durans].	25.26	574	348	25	103	635	81	614	8e-14	85.5
rs:XP_009622053	PREDICTED: DNA topoisomerase 3-alpha isoform X5 [Nicotiana tomentosiformis].	22.96	636	395	24	3	585	14	607	8e-14	85.5
rs:WP_039036869	DNA topoisomerase I [Pseudoalteromonas sp. ECSMB14103].	23.40	611	388	22	60	631	72	641	8e-14	85.5
tr:B6AM76_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.03	673	414	29	3	631	52	664	8e-14	85.5
rs:WP_042093035	hypothetical protein, partial [Escherichia coli].	28.51	221	132	7	1	199	1	217	8e-14	81.6
rs:WP_005838811	MULTISPECIES: DNA topoisomerase I [Bacteroides].	24.78	561	353	19	77	617	54	565	8e-14	85.5
rs:WP_033960908	DNA topoisomerase I [Psychroserpens sp. PAMC 27130].	23.22	659	402	23	3	621	5	599	8e-14	85.5
rs:WP_027553089	DNA topoisomerase I [Bradyrhizobium sp. Cp5.3].	23.80	685	414	28	1	630	1	632	8e-14	85.5
rs:XP_002144156	DNA topoisomerase III, putative [Talaromyces marneffei ATCC 18224].	22.24	652	382	23	3	573	7	614	8e-14	85.1
tr:I6H5Q7_SHIFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	24.76	412	251	14	252	633	15	397	8e-14	85.1
rs:WP_046653556	DNA topoisomerase I [Brevundimonas diminuta].	22.58	558	337	18	1	520	1	501	8e-14	85.5
rs:WP_044433901	DNA topoisomerase I [Acinetobacter ursingii].	23.01	478	292	15	187	629	213	649	8e-14	85.5
rs:WP_007108079	DNA topoisomerase I [Natrinema altunense].	23.35	514	333	18	1	480	1	487	8e-14	85.9
rs:WP_041201251	DNA topoisomerase I, partial [Helicobacter pylori].	23.87	486	332	14	75	536	46	517	8e-14	84.7
rs:WP_023573513	DNA topoisomerase I [Flavobacterium enshiense].	24.58	533	328	20	3	521	5	477	8e-14	85.5
rs:WP_023605764	DNA topoisomerase 1 [Vagococcus lutrae].	22.50	671	420	25	3	635	6	614	9e-14	85.1
rs:WP_003598643	MULTISPECIES: DNA topoisomerase I [Lactobacillus casei group].	23.91	573	370	18	90	629	68	607	9e-14	85.1
rs:WP_035025623	MULTISPECIES: DNA topoisomerase I [Proteobacteria].	21.48	689	426	26	1	630	1	633	9e-14	85.5
tr:E6QI81_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CBI06946.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI06946.1};	24.83	600	355	21	79	616	31	596	9e-14	85.5
tr:A0A090VZV9_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.05	535	323	20	3	521	5	477	9e-14	85.1
rs:WP_004382933	DNA topoisomerase I [Prevotella veroralis].	23.43	606	366	21	3	580	5	540	9e-14	85.5
rs:WP_014518289	DNA topoisomerase I [Chlamydia pneumoniae].	23.84	583	332	20	3	534	5	526	9e-14	85.5
tr:A0A0D1JJ80_9LACT	SubName: Full=TopB_2 protein {ECO:0000313|EMBL:KIU21473.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIU21473.1};	29.22	243	144	10	461	676	7	248	9e-14	82.0
rs:WP_021891351	DNA topoisomerase [Bacteroides sp. CAG:20].	23.32	536	343	16	3	526	5	484	9e-14	85.5
rs:WP_012167784	DNA topoisomerase I [Acaryochloris marina].	24.32	588	353	22	74	614	54	596	9e-14	85.1
rs:XP_003588648	DNA topoisomerase [Medicago truncatula].	26.29	388	228	16	64	408	179	551	9e-14	85.1
rs:WP_020083156	topoisomerase I [gamma proteobacterium SCGC AAA160-D02].	23.28	610	360	20	76	633	93	646	9e-14	85.5
rs:WP_044356176	DNA topoisomerase III, partial [Paenibacillus sp. E194].	26.38	254	152	6	375	615	1	232	9e-14	82.8
tr:A9EHJ0_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.57	607	369	20	74	631	104	658	9e-14	85.5
rs:WP_003442601	DNA topoisomerase I [Psychroflexus gondwanensis].	24.76	618	379	20	3	601	5	555	9e-14	85.5
rs:WP_032536933	MULTISPECIES: DNA topoisomerase I [Bacteroides].	24.04	628	371	27	3	604	5	552	9e-14	85.5
rs:WP_044819207	hypothetical protein [Escherichia coli].	35.04	117	66	4	1	113	1	111	9e-14	81.3
rs:WP_022085983	GTP-sensing transcriptional pleiotropic repressor CodY [Roseburia sp. CAG:197].	23.95	622	393	20	90	675	67	644	9e-14	85.1
tr:W7C9Q7_9LIST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	22.69	454	305	13	154	584	13	443	9e-14	84.3
rs:WP_045167865	DNA topoisomerase I [Prevotella intermedia].	22.43	602	377	18	3	580	5	540	9e-14	85.5
gpu:CP009505_1133	DNA topoisomerase I [Methanosarcina sp. MTP4]	23.78	635	404	23	21	616	27	620	9e-14	85.5
tr:A0A091S7V4_NESNO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.65	482	302	17	188	634	224	674	9e-14	85.5
sp:TOP1_TREPA	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	23.36	458	298	12	186	618	175	604	9e-14	85.1
rs:WP_015453828	hypothetical protein [Helicobacter cinaedi].	22.78	518	325	16	103	575	71	558	9e-14	85.1
rs:WP_017445700	hypothetical protein [Gayadomonas joobiniege].	23.01	652	405	22	74	680	85	684	9e-14	85.5
rs:WP_008751513	DNA topoisomerase I [Lachnoanaerobaculum saburreum].	22.54	568	354	20	90	616	67	589	9e-14	85.1
rs:WP_005845602	DNA topoisomerase I [Prevotella dentalis].	24.22	545	329	19	3	526	5	486	9e-14	85.1
rs:WP_044644877	DNA topoisomerase I [Paenibacillus terrae].	22.38	563	381	19	103	636	80	615	9e-14	85.1
rs:WP_031482315	DNA topoisomerase I [Desulfovibrio frigidus].	20.69	696	451	20	3	659	5	638	9e-14	85.5
rs:WP_043597838	DNA topoisomerase I [Aeromonas diversa].	22.84	486	297	14	186	633	192	637	9e-14	85.5
tr:U2KJL7_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.16	626	387	21	3	602	7	564	9e-14	85.1
tr:A0A0D3FE73_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OBART03G04820.3};	23.06	425	260	14	188	585	186	570	9e-14	85.5
rs:WP_011514221	topoisomerase I [Psychrobacter cryohalolentis].	23.88	645	399	24	77	673	108	708	9e-14	85.5
tr:G1QHD0_NOMLE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.28	416	262	13	188	585	168	548	9e-14	84.7
rs:WP_036100200	DNA topoisomerase I [Leptotrichia sp. oral taxon 215].	25.65	616	360	23	2	587	4	551	9e-14	85.1
tr:U2RB34_9FUSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.65	616	360	23	2	587	7	554	9e-14	85.1
tr:A0A0E0GH83_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA03G04610.1};	21.56	733	445	31	3	653	14	698	9e-14	85.5
rs:WP_009393140	DNA topoisomerase I [Acinetobacter sp. WC-141].	23.32	579	357	19	90	629	116	646	9e-14	85.5
rs:WP_034061439	DNA topoisomerase I [Lacinutrix sp. PAMC 27137].	24.07	540	323	18	3	521	5	478	9e-14	85.5
rs:WP_039497466	DNA topoisomerase I [Pseudoalteromonas elyakovii].	23.09	602	381	23	72	633	84	643	9e-14	85.5
tr:A0A0E0B042_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OGLUM09G02660.1};	22.05	508	322	17	188	653	160	635	1e-13	85.1
rs:WP_021668885	hypothetical protein, partial [Prevotella disiens].	37.84	148	79	4	68	204	2	147	1e-13	81.6
rs:XP_003326221	DNA topoisomerase III [Puccinia graminis f. sp. tritici CRL 75-36-700-3].	21.09	626	416	22	3	584	64	655	1e-13	85.5
rs:WP_017172747	hypothetical protein, partial [Xanthomonas axonopodis].	30.82	146	83	4	1	135	1	139	1e-13	80.1
rs:WP_041971679	DNA topoisomerase I [Geobacter sp. OR-1].	22.95	610	369	21	76	630	53	616	1e-13	85.1
rs:WP_016971647	topoisomerase I [Pseudomonas tolaasii].	23.88	490	312	14	77	541	62	515	1e-13	84.7
rs:XP_008815780	DNA topoisomerase III [Plasmodium inui San Antonio 1].	23.42	649	347	24	3	555	7	601	1e-13	85.1
rs:WP_043842115	DNA topoisomerase I [Roseivivax atlanticus].	21.42	719	418	23	1	630	1	661	1e-13	85.5
tr:A0A091PZ42_LEPDC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.43	483	298	18	188	634	179	630	1e-13	85.5
rs:WP_011361129	DNA topoisomerase I [Chlorobium chlorochromatii].	25.30	664	408	24	3	629	15	627	1e-13	85.1
rs:WP_004380549	DNA topoisomerase I [Prevotella oulorum].	23.42	602	366	22	3	580	5	535	1e-13	85.1
tr:K2A8D8_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.61	682	404	26	1	629	1	618	1e-13	85.1
rs:WP_010373951	MULTISPECIES: topoisomerase I [Pseudoalteromonas].	23.09	602	381	23	72	633	84	643	1e-13	85.1
rs:WP_014709083	DNA topoisomerase I [Prevotella intermedia].	22.43	602	377	18	3	580	5	540	1e-13	85.1
rs:WP_026788352	DNA topoisomerase I [Planktothrix rubescens].	22.09	652	393	18	3	587	4	607	1e-13	85.5
rs:WP_036080422	DNA topoisomerase [Leptospirillum ferriphilum].	22.88	673	415	29	3	631	1	613	1e-13	85.1
rs:WP_027885936	DNA topoisomerase I [Mesonia mobilis].	23.96	672	383	23	3	618	5	604	1e-13	85.1
rs:WP_044079149	DNA topoisomerase I [Prevotella salivae].	23.16	626	387	21	3	602	5	562	1e-13	85.1
rs:WP_025651317	MULTISPECIES: DNA topoisomerase I [Psychrobacter].	24.02	637	404	23	77	673	104	700	1e-13	85.1
rs:WP_016368026	DNA topoisomerase I [Lactobacillus paracasei].	24.08	573	369	18	90	629	68	607	1e-13	85.1
rs:WP_039129205	DNA topoisomerase I [Flavihumibacter sp. ZG627].	24.58	541	334	17	3	525	5	489	1e-13	85.1
rs:WP_010559875	topoisomerase I [Pseudoalteromonas spongiae].	23.24	482	290	18	187	629	197	637	1e-13	85.1
rs:WP_036907504	DNA topoisomerase I [Prevotella salivae].	23.16	626	387	21	3	602	5	562	1e-13	85.1
rs:WP_008668551	MULTISPECIES: DNA topoisomerase I [Bacteroides].	24.78	561	353	19	77	617	54	565	1e-13	85.1
rs:WP_035044009	DNA topoisomerase I [Caulobacter henricii].	21.76	694	412	23	1	630	1	627	1e-13	85.1
rs:WP_029787961	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	32.23	121	74	3	1	118	1	116	1e-13	79.7
rs:WP_045434910	DNA topoisomerase I [Acinetobacter calcoaceticus].	23.32	579	357	19	90	629	116	646	1e-13	85.1
rs:WP_043310071	DNA topoisomerase I [Pseudomonas sp. ML96].	22.53	475	302	13	186	629	195	634	1e-13	85.1
rs:WP_006334965	DNA topoisomerase 1 [Mesorhizobium sp. STM 4661].	21.86	700	410	24	1	630	1	633	1e-13	85.1
rs:WP_024356505	DNA topoisomerase I [Leucobacter chironomi].	23.69	591	342	21	2	530	6	549	1e-13	85.5
rs:WP_025069710	DNA topoisomerase I [Prevotella oulorum].	23.26	602	367	22	3	580	5	535	1e-13	85.1
rs:XP_009419964	PREDICTED: uncharacterized protein LOC103999822 [Musa acuminata subsp. malaccensis].	23.75	522	316	20	64	536	349	837	1e-13	85.5
rs:WP_011167080	DNA topoisomerase I [Mycoplasma mycoides].	23.03	673	397	30	3	625	4	605	1e-13	84.7
rs:WP_014953328	DNA topoisomerase I [alpha proteobacterium HIMB5].	22.19	685	419	26	1	629	1	627	1e-13	85.1
rs:WP_040504074	hypothetical protein, partial [Leucothrix mucor].	23.78	593	337	27	1	534	3	539	1e-13	85.1
rs:WP_029345828	DNA topoisomerase I [Lactococcus garvieae].	24.55	558	353	22	103	630	109	628	1e-13	85.1
rs:XP_009807307	PREDICTED: DNA topoisomerase 3-alpha [Gavia stellata].	24.64	483	297	18	188	634	212	663	1e-13	85.5
rs:WP_045078116	DNA topoisomerase I [Peptoniphilus sp. 1-1].	22.39	710	442	25	3	675	5	642	1e-13	85.1
rs:WP_015186585	DNA topoisomerase I [Gloeocapsa sp. PCC 7428].	22.74	620	389	18	3	574	4	581	1e-13	85.1
tr:K1XW10_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.32	475	272	20	76	520	52	478	1e-13	85.1
rs:WP_004993992	DNA topoisomerase I [Acinetobacter ursingii].	23.01	478	292	15	187	629	213	649	1e-13	85.1
rs:WP_022262390	DNA topoisomerase [Butyrivibrio sp. CAG:318].	23.72	565	350	21	90	616	67	588	1e-13	85.1
rs:WP_006011464	DNA topoisomerase I [Glaciecola pallidula].	23.80	605	380	23	65	629	75	638	1e-13	85.1
rs:WP_025276168	DNA topoisomerase I [Helicobacter pylori].	24.13	634	405	22	75	658	46	653	1e-13	84.7
rs:WP_033150319	DNA topoisomerase I [Prevotella sp. RM4].	22.84	626	384	24	3	600	5	559	1e-13	85.1
rs:WP_027104711	DNA topoisomerase I [Lachnospiraceae bacterium V9D3004].	23.63	622	386	23	90	671	67	639	1e-13	84.7
rs:WP_044315429	DNA topoisomerase III, partial [Pseudomonas stutzeri].	25.48	208	150	2	379	581	2	209	1e-13	81.6
tr:A0A009FW92_ACIBA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.21	475	290	15	187	629	188	624	1e-13	85.1
rs:WP_004991376	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	23.01	478	292	15	187	629	213	649	1e-13	85.1
rs:WP_028317283	DNA topoisomerase I [Desulfobulbus elongatus].	24.74	578	343	25	72	614	45	565	1e-13	84.7
rs:WP_010478322	endonuclease [Thermococcus zilligii].	23.86	415	226	12	307	655	827	1217	1e-13	85.5
rs:WP_010478322	endonuclease [Thermococcus zilligii].	25.45	330	210	10	3	310	4	319	1e-10	75.5
rs:WP_014281069	DNA topoisomerase I [Paenibacillus terrae].	22.38	563	381	19	103	636	80	615	1e-13	84.7
tr:C0NGZ5_AJECG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.08	643	401	22	3	586	6	607	1e-13	84.7
rs:WP_045171440	DNA topoisomerase I [Ehrlichia mineirensis].	25.04	691	393	30	1	629	1	628	1e-13	85.1
rs:WP_036846973	DNA topoisomerase I [Photorhabdus temperata].	22.80	614	361	21	75	633	79	634	1e-13	85.1
rs:WP_010526611	DNA topoisomerase I [Thermophagus xiamenensis].	26.67	405	239	13	3	392	12	373	1e-13	85.1
rs:XP_006581777	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Glycine max].	24.38	402	240	12	188	560	212	578	1e-13	85.1
rs:WP_026722768	DNA topoisomerase I [Fischerella sp. PCC 9431].	26.24	503	297	16	100	564	82	548	1e-13	84.7
rs:WP_025633988	hypothetical protein [Vibrio parahaemolyticus].	23.80	647	350	29	30	560	28	647	1e-13	85.1
rs:XP_009090020	PREDICTED: DNA topoisomerase 3-alpha [Serinus canaria].	24.90	482	297	18	188	634	239	690	1e-13	85.1
rs:WP_009800677	DNA topoisomerase I [Oceanicaulis sp. HTCC2633].	22.28	709	392	29	1	630	1	629	1e-13	85.1
rs:WP_016363891	DNA topoisomerase I, partial [Lactobacillus paracasei].	23.91	573	370	18	90	629	68	607	1e-13	84.7
rs:XP_009930649	PREDICTED: DNA topoisomerase 3-alpha [Opisthocomus hoazin].	24.43	483	298	18	188	634	241	692	1e-13	85.1
rs:WP_016368965	DNA topoisomerase I, partial [Lactobacillus paracasei].	24.08	573	369	18	90	629	21	560	1e-13	84.7
rs:WP_008885444	DNA topoisomerase I [Citreicella sp. SE45].	24.76	416	250	15	1	391	1	378	1e-13	85.1
rs:WP_039204962	DNA topoisomerase I [Aphanizomenon flos-aquae].	25.90	583	341	24	79	610	59	601	1e-13	84.7
rs:WP_014889101	topoisomerase I [secondary endosymbiont of Heteropsylla cubana].	23.48	477	315	12	74	533	77	520	1e-13	85.1
rs:WP_005001350	DNA topoisomerase I [Acinetobacter ursingii].	23.01	478	292	15	187	629	213	649	1e-13	85.1
rs:YP_009052166	putative DNA topoisomerase IA [Aureococcus anophagefferens virus].	28.06	449	251	18	89	520	59	452	1e-13	84.7
tr:E6MQ03_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.16	626	387	21	3	602	22	579	1e-13	85.1
rs:WP_011979781	DNA topoisomerase I [Sulfurovum sp. NBC37-1].	22.76	659	415	21	3	629	4	600	1e-13	84.7
rs:WP_003599338	DNA topoisomerase I [Methylobacterium extorquens].	23.55	688	410	29	1	629	1	631	1e-13	85.1
rs:WP_011282147	DNA topoisomerase I [Candidatus Pelagibacter ubique].	22.99	696	400	31	1	629	1	627	1e-13	85.1
rs:XP_005997515	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Latimeria chalumnae].	22.75	488	300	16	188	634	233	684	1e-13	85.1
rs:WP_046847126	DNA topoisomerase I [Hyphomicrobium sp. GJ21].	24.91	558	336	22	55	557	27	556	1e-13	85.1
rs:WP_016856973	topoisomerase I [Candidatus Hamiltonella defensa].	22.62	588	390	16	74	631	82	634	1e-13	85.1
rs:WP_018463724	DNA topoisomerase I [Prevotella paludivivens].	23.04	599	372	19	3	580	5	535	1e-13	84.7
rs:XP_005494941	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Zonotrichia albicollis].	24.90	482	297	18	188	634	239	690	1e-13	85.1
rs:WP_006838846	DNA topoisomerase I, partial [Bacillus sp. SG-1].	24.45	454	293	16	90	520	67	493	1e-13	84.3
rs:WP_032528281	DNA topoisomerase III, partial [Bacteroides fragilis].	36.84	114	56	4	3	109	1	105	1e-13	79.0
rs:XP_009581158	PREDICTED: DNA topoisomerase 3-alpha [Fulmarus glacialis].	24.79	484	295	19	188	634	241	692	1e-13	85.1
rs:XP_005997513	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Latimeria chalumnae].	22.75	488	300	16	188	634	233	684	1e-13	85.1
rs:WP_046416095	DNA topoisomerase I [Bacteroides sp. UNK.MGS-13].	23.32	536	343	16	3	526	5	484	1e-13	84.7
rs:XP_005017065	PREDICTED: DNA topoisomerase 3-alpha [Anas platyrhynchos].	24.22	483	299	18	188	634	241	692	1e-13	85.1
rs:WP_013199013	topoisomerase I [Acinetobacter oleivorans].	22.65	574	367	17	90	629	116	646	1e-13	85.1
rs:WP_027872607	DNA topoisomerase I [Spongiibacter marinus].	22.24	607	371	21	74	633	93	645	1e-13	85.1
rs:WP_022286039	DNA topoisomerase [Bacteroides sp. CAG:770].	24.65	503	317	15	76	544	123	597	1e-13	85.1
rs:WP_009119214	DNA topoisomerase I [Neisseria shayeganii].	21.27	616	392	20	70	630	37	614	1e-13	84.7
rs:WP_027753040	DNA topoisomerase I [Streptomyces sp. CNH099].	24.20	595	328	23	2	530	9	546	1e-13	85.1
rs:WP_035709856	DNA topoisomerase I [Bradyrhizobium sp. CCBAU 43298].	22.76	703	433	24	1	647	1	649	1e-13	85.1
rs:WP_027022206	DNA topoisomerase I [Conchiformibius steedae].	22.37	617	385	21	70	630	37	615	1e-13	84.7
rs:WP_025278686	DNA topoisomerase I [Barnesiella viscericola].	22.10	620	389	22	3	604	5	548	1e-13	84.7
rs:XP_006581776	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Glycine max].	24.38	402	240	12	188	560	212	578	1e-13	85.1
rs:WP_032131555	DNA topoisomerase I [Weeksella sp. FF8].	24.49	535	327	16	3	521	5	478	1e-13	84.7
rs:WP_047000611	DNA topoisomerase I [Clostridium beijerinckii].	24.45	548	343	16	103	618	80	588	1e-13	84.7
rs:WP_010488381	MULTISPECIES: DNA topoisomerase I [Lactobacillus casei group].	23.39	573	373	17	90	629	68	607	1e-13	84.7
rs:XP_009622052	PREDICTED: DNA topoisomerase 3-alpha isoform X4 [Nicotiana tomentosiformis].	22.96	636	395	24	3	585	14	607	1e-13	84.7
rs:WP_017261889	DNA topoisomerase I [Lactobacillus rossiae].	22.18	568	381	18	90	629	80	614	1e-13	84.7
rs:WP_005689318	DNA topoisomerase I [Lactobacillus rhamnosus].	23.70	578	365	19	90	629	68	607	1e-13	84.7
tr:G2YR43_BOTF4	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.51	553	355	21	3	520	6	525	1e-13	84.7
rs:WP_045136213	DNA topoisomerase I [Lactobacillus paracasei].	23.91	573	370	18	90	629	68	607	1e-13	84.7
rs:WP_039638996	DNA topoisomerase I [Lactobacillus sp. FMNP02].	23.39	573	373	17	90	629	68	607	1e-13	84.7
rs:WP_027530037	DNA topoisomerase I [Bradyrhizobium sp. WSM3983].	22.30	686	423	23	1	630	1	632	1e-13	84.7
rs:WP_019134346	hypothetical protein [Kallipyga massiliensis].	22.07	666	413	27	2	629	4	601	1e-13	84.7
rs:WP_027115901	DNA topoisomerase I [Lachnospiraceae bacterium P6B14].	21.21	646	408	22	83	658	60	674	1e-13	84.7
rs:WP_015694903	DNA topoisomerase I [Melissococcus plutonius].	24.74	578	373	21	90	635	68	615	1e-13	84.7
tr:C0B640_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEG91174.1};	31.86	204	126	6	479	675	1	198	1e-13	80.9
rs:WP_028467444	DNA topoisomerase I [Nisaea denitrificans].	23.55	722	424	33	1	656	1	660	1e-13	84.7
rs:WP_027598369	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	24.00	475	301	15	187	633	195	637	1e-13	84.7
rs:WP_046550239	DNA topoisomerase I [Sulfurovum lithotrophicum].	22.81	662	411	23	3	629	4	600	1e-13	84.7
rs:WP_029785268	DNA topoisomerase III, partial [Escherichia coli].	29.13	206	128	6	30	223	1	200	1e-13	81.3
rs:WP_006774712	DNA topoisomerase I [[Clostridium] hathewayi].	23.43	461	289	12	187	616	71	498	1e-13	84.3
rs:WP_009388753	DNA topoisomerase I [Capnocytophaga sp. oral taxon 329].	26.17	447	273	16	93	521	70	477	1e-13	84.7
tr:R1YUH1_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.28	189	118	4	219	400	1	186	1e-13	80.9
rs:WP_028163942	DNA topoisomerase I [Bradyrhizobium elkanii].	22.14	691	418	29	1	630	1	632	1e-13	84.7
rs:WP_005232311	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	24.21	475	290	15	187	629	212	648	1e-13	84.7
rs:WP_042071334	DNA topoisomerase III, partial [Escherichia coli].	35.04	117	66	4	1	113	1	111	1e-13	79.7
tr:D5EXD2_PRER2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.29	601	367	23	3	580	5	534	1e-13	84.7
rs:WP_031542288	DNA topoisomerase I [Mesoplasma photuris].	23.26	645	411	24	3	616	4	595	1e-13	84.3
rs:WP_016370883	DNA topoisomerase I, partial [Lactobacillus paracasei].	23.74	556	362	16	90	616	68	590	1e-13	84.3
tr:F5SPD8_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.14	642	398	22	77	673	97	694	1e-13	84.7
rs:WP_035358751	DNA topoisomerase I, partial [Acholeplasma multilocale].	25.89	394	245	12	3	385	5	362	1e-13	84.3
tr:W4RZL4_9XANT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE49104.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAE49104.1};	26.36	258	162	7	386	629	8	251	1e-13	81.6
rs:WP_021680539	DNA topoisomerase I [Ruminococcus callidus].	22.98	605	383	22	55	616	28	592	1e-13	84.7
rs:WP_034549947	hypothetical protein, partial [Helicobacter fennelliae].	22.67	591	376	16	76	629	53	599	1e-13	84.7
rs:WP_006778033	DNA topoisomerase III, partial [[Clostridium] hathewayi].	30.63	160	106	3	245	400	35	193	1e-13	80.9
rs:WP_045721371	DNA topoisomerase I, partial [Salmonella enterica].	24.95	469	299	16	73	520	74	510	1e-13	84.0
rs:WP_022310620	DNA topoisomerase [Prevotella sp. CAG:474].	23.37	599	369	21	3	580	5	534	1e-13	84.7
tr:F0WXN4_9STRA	RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};	24.17	484	290	15	172	616	226	671	1e-13	85.1
tr:U3TRG9_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.60	374	221	11	187	536	190	526	1e-13	84.0
rs:WP_040177470	DNA topoisomerase III, partial [Klebsiella pneumoniae].	26.94	271	175	11	1	255	1	264	1e-13	81.6
rs:WP_013245718	DNA topoisomerase I [Lactobacillus casei].	23.91	573	370	18	90	629	68	607	1e-13	84.7
rs:XP_005997514	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Latimeria chalumnae].	22.75	488	300	16	188	634	233	684	1e-13	84.7
rs:WP_046101912	DNA topoisomerase I [Pantoea anthophila].	23.15	596	381	23	75	633	79	634	1e-13	84.7
rs:XP_010291976	PREDICTED: DNA topoisomerase 3-alpha [Phaethon lepturus].	23.81	483	301	16	188	634	241	692	1e-13	84.7
rs:WP_005037005	DNA topoisomerase I [Acinetobacter calcoaceticus].	23.32	579	357	18	90	629	116	646	1e-13	84.7
rs:WP_028909395	DNA topoisomerase I [Prevotella sp. AGR2160].	23.65	537	330	17	3	520	5	480	1e-13	84.7
tr:K1S014_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC48684.1}; Flags: Fragment;	32.54	169	94	5	1	157	1	161	1e-13	80.1
tr:K1S9N2_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC44181.1}; Flags: Fragment;	36.04	111	67	3	41	148	1	110	1e-13	79.3
rs:WP_013714771	topoisomerase I [Pseudomonas mendocina].	22.89	485	296	12	186	633	195	638	1e-13	84.7
rs:WP_022707724	DNA topoisomerase I [Paracoccus zeaxanthinifaciens].	22.12	669	391	23	55	630	27	658	1e-13	84.7
rs:WP_021669643	DNA topoisomerase I [Prevotella disiens].	23.18	604	370	20	3	580	24	559	1e-13	84.7
rs:WP_043917610	DNA topoisomerase I [Jannaschia aquimarina].	21.76	726	406	30	1	630	1	660	1e-13	84.7
rs:WP_041894333	DNA topoisomerase I [Myroides profundi].	25.56	532	324	19	3	521	5	477	2e-13	84.7
rs:WP_022222304	DNA topoisomerase [Firmicutes bacterium CAG:170].	23.03	595	380	21	88	640	65	623	2e-13	84.7
rs:WP_046418721	DNA topoisomerase I [Xylella fastidiosa].	23.56	573	350	20	3	538	5	526	2e-13	84.7
rs:WP_027420405	DNA topoisomerase I [Crocinitomix catalasitica].	25.47	632	338	23	3	574	5	563	2e-13	84.7
rs:WP_037372277	DNA topoisomerase I [Selenomonas noxia].	21.42	663	438	20	3	636	33	641	2e-13	84.7
rs:WP_036908284	DNA topoisomerase I, partial [Prevotella ruminicola].	23.29	601	367	23	3	580	5	534	2e-13	84.7
rs:WP_027665389	DNA topoisomerase I [Rhizobium leguminosarum].	22.60	668	395	27	38	630	16	636	2e-13	84.7
rs:WP_021991100	DNA topoisomerase [Prevotella sp. CAG:1092].	24.14	551	322	20	3	526	15	496	2e-13	84.7
rs:WP_008209996	DNA topoisomerase I [Rhodanobacter sp. 115].	22.83	508	315	15	77	538	54	530	2e-13	84.7
tr:W1F1E9_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.49	494	307	21	73	539	74	528	2e-13	84.0
tr:K2EGY6_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.08	681	399	26	1	644	1	600	2e-13	84.3
rs:WP_044297986	DNA topoisomerase I [Psychrobacter sp. 1501(2011)].	24.14	642	398	22	77	673	100	697	2e-13	84.7
tr:F0WXN8_9STRA	RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};	24.17	484	290	15	172	616	226	671	2e-13	85.1
rs:WP_004674582	DNA topoisomerase I [Acinetobacter parvus].	23.18	578	359	18	90	629	117	647	2e-13	84.7
rs:WP_006317433	DNA topoisomerase I [Caldisalinibacter kiritimatiensis].	24.06	561	353	18	90	616	67	588	2e-13	84.3
tr:T1CRF0_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.67	591	376	16	76	629	53	599	2e-13	84.3
rs:WP_034471440	DNA topoisomerase I [Afipia sp. P52-10].	23.41	692	407	29	1	629	1	632	2e-13	84.7
tr:A0A091VY07_OPIHO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.43	483	298	18	188	634	221	672	2e-13	84.7
rs:WP_005488609	DNA topoisomerase I [Halanaerobium saccharolyticum].	24.58	594	349	24	83	629	63	604	2e-13	84.3
rs:XP_005990295	PREDICTED: DNA topoisomerase 3-beta-1 [Latimeria chalumnae].	22.80	614	396	20	3	564	5	592	2e-13	84.7
rs:WP_017391319	topoisomerase I [Acinetobacter calcoaceticus].	23.32	579	357	18	90	629	116	646	2e-13	84.7
rs:WP_003565415	MULTISPECIES: DNA topoisomerase I [Lactobacillus casei group].	23.91	573	370	18	90	629	68	607	2e-13	84.3
rs:WP_045625031	DNA topoisomerase I [Lactobacillus paracasei].	23.91	573	370	18	90	629	68	607	2e-13	84.3
rs:WP_040571153	DNA topoisomerase I [Selenomonas noxia].	21.42	663	438	20	3	636	33	641	2e-13	84.3
rs:WP_006264644	DNA topoisomerase I [Myroides odoratimimus].	25.56	536	319	20	3	521	5	477	2e-13	84.7
rs:WP_003164641	DNA topoisomerase I [Brevundimonas diminuta].	22.40	558	338	18	1	520	1	501	2e-13	84.7
tr:D4S8C7_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.42	663	438	20	3	636	44	652	2e-13	84.3
rs:WP_006259653	DNA topoisomerase I [Myroides odoratimimus].	25.56	536	319	20	3	521	5	477	2e-13	84.7
rs:WP_004680559	DNA topoisomerase I [Acinetobacter parvus].	23.18	578	359	18	90	629	117	647	2e-13	84.7
rs:WP_040172041	DNA topoisomerase I [Phaeobacter sp. S26].	25.97	412	250	16	1	391	1	378	2e-13	84.7
rs:WP_006266880	DNA topoisomerase I [Myroides odoratimimus].	25.56	536	319	20	3	521	5	477	2e-13	84.7
rs:WP_039328605	DNA topoisomerase I [Myroides sp. A21].	25.56	536	319	20	3	521	5	477	2e-13	84.7
rs:WP_005239880	MULTISPECIES: topoisomerase I [Acinetobacter].	23.01	578	360	18	90	629	117	647	2e-13	84.7
rs:WP_041841686	DNA topoisomerase I [Actinoplanes friuliensis].	23.31	635	369	25	2	571	9	590	2e-13	84.7
rs:WP_014346412	DNA topoisomerase [Pyrobaculum oguniense].	21.49	591	395	18	1	560	1	553	2e-13	84.0
tr:I1BYY5_RHIO9	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.29	507	299	16	152	631	147	585	2e-13	84.3
tr:A0A0E0CVM2_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OMERI03G04540.1};	22.10	638	372	25	3	585	14	581	2e-13	84.7
rs:WP_039715725	DNA topoisomerase I [Scytonema millei].	22.24	607	373	16	3	560	4	560	2e-13	84.7
rs:WP_017999241	DNA topoisomerase I [Paracoccus sp. N5].	23.23	650	401	24	55	648	27	634	2e-13	84.7
rs:WP_040152278	DNA topoisomerase III, partial [Xanthomonas citri].	28.10	210	136	6	188	382	18	227	2e-13	80.9
rs:WP_016206342	DNA topoisomerase I [Clostridium sartagoforme].	24.45	548	343	16	103	618	80	588	2e-13	84.3
rs:WP_041077404	hypothetical protein [Thermotoga caldifontis].	24.80	512	311	16	82	574	645	1101	2e-13	84.7
rs:WP_034855894	DNA topoisomerase I [Ignatzschineria larvae].	24.95	489	310	17	79	534	57	521	2e-13	84.3
rs:WP_009089965	topoisomerase I [Pantoea sp. Sc1].	23.15	596	381	23	75	633	79	634	2e-13	84.7
rs:WP_009106404	DNA topoisomerase I [Desulfovibrio sp. U5L].	23.74	594	368	21	76	629	53	601	2e-13	84.3
tr:F0WXN6_9STRA	RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};	24.17	484	290	15	172	616	226	671	2e-13	85.1
rs:WP_010705324	DNA topoisomerase I [Bartonella vinsonii].	23.91	690	407	29	1	629	1	633	2e-13	84.3
tr:C6H6Z0_AJECH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.26	638	406	21	3	586	6	607	2e-13	84.3
rs:WP_003654752	topoisomerase I [Acinetobacter calcoaceticus].	23.32	579	357	18	90	629	116	646	2e-13	84.7
tr:T0TNZ7_LACLC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	24.50	404	248	15	249	629	29	398	2e-13	83.6
rs:NP_224964	DNA topoisomerase I [Chlamydophila pneumoniae CWL029].	23.84	583	332	20	3	534	5	526	2e-13	84.7
rs:WP_012254575	DNA topoisomerase I [Methylobacterium extorquens].	23.55	688	410	29	1	629	1	631	2e-13	84.7
rs:WP_044195038	DNA topoisomerase I [Ehrlichia sp. HF].	23.80	748	425	29	1	671	1	680	2e-13	84.3
rs:WP_018835882	MULTISPECIES: DNA topoisomerase I [Streptomyces].	24.20	595	329	23	2	530	9	547	2e-13	84.7
rs:WP_037753604	DNA topoisomerase I [Streptomyces sp. CNQ-525].	24.20	595	329	23	2	530	9	547	2e-13	84.7
rs:WP_016650340	DNA topoisomerase I [Myroides odoratimimus].	25.56	536	319	20	3	521	5	477	2e-13	84.3
tr:F0WXN1_9STRA	RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};	24.17	484	290	15	172	616	226	671	2e-13	85.1
rs:WP_007226908	topoisomerase I [marine gamma proteobacterium HTCC2143].	22.49	587	375	21	83	633	99	641	2e-13	84.7
rs:WP_018052407	hypothetical protein [Marinimicrobia bacterium SCGC AB-629-J13].	24.00	625	364	21	3	577	6	569	2e-13	84.3
tr:A0A091UUX7_PHALP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.02	483	300	17	188	634	221	672	2e-13	84.7
rs:XP_816014	DNA topoisomerase III [Trypanosoma cruzi strain CL Brener].	21.64	587	356	22	46	582	55	587	2e-13	84.7
tr:U5VSI3_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.31	635	369	25	2	571	11	592	2e-13	84.7
rs:WP_024098242	DNA topoisomerase I [Phaeobacter gallaeciensis].	25.97	412	250	16	1	391	1	378	2e-13	84.7
tr:F0WXN7_9STRA	RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};	24.17	484	290	15	172	616	226	671	2e-13	85.1
rs:WP_005278819	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	23.01	578	360	18	90	629	117	647	2e-13	84.3
rs:WP_045657725	DNA topoisomerase I [Clostridiaceae bacterium BRH_c20a].	21.48	647	412	20	3	616	8	591	2e-13	84.3
rs:WP_034518694	DNA topoisomerase I [Agrobacterium rhizogenes].	22.27	660	408	27	38	630	16	637	2e-13	84.3
rs:WP_012594201	DNA topoisomerase I [Cyanothece sp. PCC 8801].	22.90	607	370	18	3	560	4	561	2e-13	84.3
rs:WP_013376622	DNA topoisomerase I [Stigmatella aurantiaca].	22.90	620	390	26	76	640	119	705	2e-13	84.3
tr:B9JDL6_AGRRK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.27	660	408	27	38	630	17	638	2e-13	84.3
rs:WP_004756177	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	23.18	578	359	18	90	629	117	647	2e-13	84.3
rs:WP_029896729	DNA topoisomerase I [Desulfovibrio sp. L21-Syr-AB].	23.42	679	384	28	77	679	54	672	2e-13	84.3
rs:WP_028656482	DNA topoisomerase I [Nocardioides sp. J54].	23.80	500	302	17	77	528	68	536	2e-13	84.3
rs:WP_015874127	topoisomerase I [Candidatus Hamiltonella defensa].	22.10	629	403	19	74	664	82	661	2e-13	84.3
tr:F0WXP0_9STRA	RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};	24.17	484	290	15	172	616	226	671	2e-13	85.1
tr:Q01N68_SOLUE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.28	486	319	13	76	533	53	517	2e-13	84.3
rs:WP_034297059	DNA topoisomerase I [Alloscardovia omnicolens].	24.45	589	343	20	2	538	6	544	2e-13	84.3
rs:WP_017398783	topoisomerase I [Acinetobacter pittii].	23.41	581	354	20	90	629	116	646	2e-13	84.3
rs:WP_016139347	DNA topoisomerase I [Acinetobacter calcoaceticus].	23.32	579	357	18	90	629	116	646	2e-13	84.3
rs:WP_004641017	DNA topoisomerase I [Acinetobacter calcoaceticus].	23.32	579	357	18	90	629	116	646	2e-13	84.3
rs:WP_016595154	topoisomerase I, partial [Yersinia pestis].	23.39	590	358	19	74	624	86	620	2e-13	84.0
rs:WP_043058862	DNA topoisomerase I [Mesorhizobium sp. UASWS1009].	22.21	698	426	25	2	632	15	662	2e-13	84.3
rs:WP_036825650	DNA topoisomerase I [Porphyromonadaceae bacterium COT-184 OH4590].	24.73	469	291	15	77	523	53	481	2e-13	84.3
tr:A0A093LKR5_FULGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.53	481	300	18	188	634	221	672	2e-13	84.7
rs:WP_006852033	DNA topoisomerase I [Synechococcus sp. WH 8109].	22.12	624	378	22	3	572	5	574	2e-13	84.3
rs:WP_009222712	DNA topoisomerase, partial [Peptoniphilus sp. oral taxon 386].	24.63	475	290	17	90	533	67	504	2e-13	84.0
rs:WP_015535341	DNA topoisomerase I [Faecalitalea cylindroides].	22.96	649	389	22	3	611	5	582	2e-13	84.3
tr:U9SKB6_RHIID	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ERZ96388.1}; Flags: Fragment;	22.78	619	398	23	3	577	7	589	2e-13	84.7
rs:WP_026832621	DNA topoisomerase I [Exiguobacterium undae].	23.16	665	412	26	3	630	5	607	2e-13	84.3
rs:XP_011073928	PREDICTED: DNA topoisomerase 3-beta isoform X4 [Sesamum indicum].	23.33	553	351	21	3	521	6	519	2e-13	84.3
rs:WP_017390083	topoisomerase I [Acinetobacter calcoaceticus].	23.32	579	357	18	90	629	116	646	2e-13	84.3
rs:WP_014208301	topoisomerase I [Acinetobacter calcoaceticus].	22.47	574	368	17	90	629	116	646	2e-13	84.3
rs:WP_018670812	DNA topoisomerase I [Brevibacillus laterosporus].	23.09	563	376	23	103	636	80	614	2e-13	84.3
rs:WP_020327389	DNA topoisomerase III, partial [Pseudomonas syringae].	31.77	192	117	5	427	613	3	185	2e-13	80.5
tr:J5H751_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.86	560	363	14	90	616	62	585	2e-13	84.0
rs:WP_028897255	DNA topoisomerase I [Prevotella sp. HUN102].	23.06	555	331	18	3	526	5	494	2e-13	84.3
rs:XP_005494942	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Zonotrichia albicollis].	24.64	483	297	19	188	634	110	561	2e-13	84.3
rs:WP_037220614	DNA topoisomerase I [Rhizobium sp. YR060].	22.27	660	408	27	38	630	16	637	2e-13	84.3
rs:WP_008789958	MULTISPECIES: DNA topoisomerase I [Coprobacillus].	24.35	501	300	21	164	629	142	598	2e-13	84.0
rs:WP_035619653	DNA topoisomerase I [Lachnoanaerobaculum sp. ICM7].	22.86	560	363	14	90	616	67	590	2e-13	84.0
rs:XP_006450082	hypothetical protein CICLE_v10007345mg [Citrus clementina].	22.90	677	399	32	32	630	192	823	2e-13	84.3
rs:XP_011455654	PREDICTED: DNA topoisomerase 3-alpha-like isoform X4 [Crassostrea gigas].	22.82	561	366	18	46	577	8	530	2e-13	84.3
rs:WP_015823489	DNA topoisomerase I [Methylobacterium extorquens].	23.55	688	410	29	1	629	1	631	2e-13	84.3
tr:U1QX25_9BIFI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.45	589	343	20	2	538	20	558	2e-13	84.3
rs:WP_011363601	DNA topoisomerase I [Synechococcus sp. CC9605].	22.88	625	372	24	3	572	5	574	2e-13	84.3
rs:WP_022181766	DNA topoisomerase [Firmicutes bacterium CAG:137].	25.31	407	250	16	261	640	1	380	2e-13	83.6
rs:WP_007692049	MULTISPECIES: DNA topoisomerase I [Rhizobium/Agrobacterium group].	22.27	660	408	27	38	630	16	637	2e-13	84.3
rs:WP_017124206	DNA topoisomerase I [Pseudomonas gingeri].	23.55	586	344	19	77	614	62	591	2e-13	84.0
rs:WP_017486547	DNA topoisomerase I [Methylobacterium sp. MB200].	22.71	687	417	27	1	629	1	631	2e-13	84.3
rs:WP_016168270	DNA topoisomerase I [Acinetobacter tandoii].	23.52	489	276	17	187	629	213	649	2e-13	84.3
rs:XP_005842005	hypothetical protein GUITHDRAFT_156833 [Guillardia theta CCMP2712].	22.34	667	432	22	3	619	7	637	2e-13	84.0
rs:WP_015951693	DNA topoisomerase I [Methylobacterium extorquens].	23.55	688	410	29	1	629	1	631	2e-13	84.3
rs:WP_015915683	DNA topoisomerase I [Agrobacterium vitis].	22.84	661	402	26	38	630	16	636	2e-13	84.3
rs:WP_040181922	DNA topoisomerase I [Phaeobacter sp. S60].	25.97	412	250	16	1	391	1	378	2e-13	84.3
rs:WP_045734776	DNA topoisomerase I, partial [Pseudomonas pseudoalcaligenes].	22.98	457	287	12	186	616	195	612	2e-13	84.0
rs:WP_027236761	DNA topoisomerase I [Leisingera caerulea].	22.67	697	418	29	1	630	1	643	2e-13	84.3
tr:A0A044QP20_ONCVO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.45	704	434	25	3	631	7	666	2e-13	84.3
rs:WP_022730658	DNA topoisomerase I [Thalassospira lucentensis].	22.48	703	432	28	1	647	1	646	2e-13	84.3
rs:WP_029504183	DNA topoisomerase I [Lachnoclostridium phytofermentans].	22.26	557	369	15	90	616	67	589	2e-13	84.0
tr:A0A0D3F547_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OBART02G16520.3};	23.09	628	373	27	39	610	251	824	2e-13	84.3
rs:WP_027173538	DNA topoisomerase I [Methylobacterium sp. 10].	23.26	688	412	27	1	629	1	631	2e-13	84.3
tr:A0A0E0GH84_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA03G04610.2};	22.00	641	394	26	3	585	14	606	2e-13	84.3
rs:XP_011455653	PREDICTED: DNA topoisomerase 3-alpha-like isoform X3 [Crassostrea gigas].	22.82	561	366	18	46	577	8	530	2e-13	84.3
rs:WP_022079531	DNA topoisomerase [Acetobacter sp. CAG:267].	22.77	685	410	25	1	629	1	622	2e-13	84.3
rs:WP_011158669	DNA topoisomerase I [Rhodopseudomonas palustris].	23.19	690	413	29	1	630	1	633	2e-13	84.3
rs:WP_023169027	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	24.95	469	299	16	73	520	74	510	2e-13	83.6
rs:WP_046434318	DNA topoisomerase I [Ruminococcus sp. UNK.MGS-30].	23.45	597	390	20	55	616	28	592	2e-13	84.0
rs:WP_017959963	DNA topoisomerase I [Rhizobium leguminosarum].	23.05	668	392	28	38	630	16	636	2e-13	84.3
tr:A0A096CWZ0_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.14	605	369	21	3	580	5	540	2e-13	84.3
rs:WP_044513401	DNA topoisomerase I [Hymenobacter sp. DG25B].	24.26	474	291	14	74	521	51	482	2e-13	84.3
rs:WP_026635325	DNA topoisomerase I [Dyella japonica].	22.55	581	350	21	3	538	5	530	2e-13	84.3
rs:XP_009869553	PREDICTED: DNA topoisomerase 3-alpha, partial [Apaloderma vittatum].	23.76	484	307	16	188	634	224	682	2e-13	84.3
rs:WP_034442673	DNA topoisomerase I [Butyrivibrio sp. AE2032].	23.08	572	344	18	2	534	4	518	2e-13	84.0
tr:A0A0E0B043_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OGLUM09G02660.2};	21.90	516	313	18	188	653	160	635	2e-13	84.3
gpu:CP009517_2395	DNA topoisomerase I [Methanosarcina barkeri 3]	23.45	631	387	27	90	670	92	676	2e-13	84.3
rs:WP_008314273	DNA topoisomerase I [Leptolyngbya sp. PCC 6406].	23.80	605	367	20	3	560	4	561	2e-13	84.3
rs:WP_028877907	DNA topoisomerase I [Terasakiella pusilla].	23.40	718	424	31	1	655	1	655	2e-13	84.3
tr:A0A0D0B157_9HOMO	SubName: Full=Unplaced genomic scaffold CY34scaffold_300, whole genome shotgun sequence {ECO:0000313|EMBL:KIK37763.1};	23.30	618	394	24	3	577	4	584	2e-13	84.3
rs:WP_036010230	DNA topoisomerase I [Leptolyngbya sp. JSC-1].	23.10	593	362	19	90	625	72	627	2e-13	84.0
rs:WP_032548942	DNA topoisomerase III, partial [Vibrio crassostreae].	40.40	99	59	0	462	560	7	105	2e-13	79.7
tr:W5MC34_LEPOC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.52	472	281	14	188	619	245	676	2e-13	84.0
rs:WP_032048758	DNA topoisomerase I [Acinetobacter baumannii].	22.65	574	367	17	90	629	116	646	2e-13	84.3
rs:WP_013337362	reverse gyrase [Vulcanisaeta distributa].	23.27	550	328	21	82	588	761	1259	2e-13	84.3
rs:WP_007553288	DNA topoisomerase I [Bartonella sp. DB5-6].	22.75	690	415	27	1	629	1	633	2e-13	84.3
rs:WP_028112289	DNA topoisomerase I [Ferrimonas kyonanensis].	23.74	476	304	14	187	633	199	644	2e-13	84.3
rs:WP_008753063	DNA topoisomerase I [Lachnoanaerobaculum saburreum].	22.54	568	354	20	90	616	67	589	2e-13	84.0
rs:WP_010181533	DNA topoisomerase I [Aquimarina agarilytica].	25.68	440	284	14	93	521	70	477	2e-13	84.0
rs:WP_038984721	DNA topoisomerase I [Myroides odoratimimus].	25.38	532	325	19	3	521	5	477	2e-13	84.0
rs:WP_036386129	DNA topoisomerase I [Muricauda sp. MAR_2010_75].	24.77	533	329	16	3	521	5	479	2e-13	84.0
rs:XP_009466099	PREDICTED: DNA topoisomerase 3-alpha [Nipponia nippon].	24.43	483	298	18	188	634	241	692	2e-13	84.3
rs:WP_041872694	DNA topoisomerase III, partial [Verrucomicrobia bacterium SCGC AAA164-O14].	30.43	184	118	5	3	178	5	186	2e-13	80.1
rs:WP_037310690	DNA topoisomerase I [Ruegeria halocynthiae].	22.37	590	348	20	1	534	1	536	2e-13	84.0
rs:XP_011455651	PREDICTED: DNA topoisomerase 3-alpha-like isoform X1 [Crassostrea gigas].	22.82	561	366	18	46	577	8	530	2e-13	84.3
rs:WP_036882691	DNA topoisomerase I [Prevotella disiens].	23.14	605	369	21	3	580	24	559	2e-13	84.0
tr:S4EPX6_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EPI19509.1}; Flags: Fragment;	31.91	141	91	4	3	139	4	143	2e-13	79.0
rs:WP_016385941	DNA topoisomerase I [Lactobacillus paracasei].	23.91	573	370	18	90	629	68	607	2e-13	84.0
rs:WP_046486836	DNA topoisomerase I [Methylophilaceae bacterium MMS-2-53].	23.59	674	412	24	2	630	3	618	2e-13	84.0
rs:XP_006656881	PREDICTED: uncharacterized protein LOC102708068 [Oryza brachyantha].	22.69	639	390	27	39	612	332	931	2e-13	84.3
rs:WP_008279117	DNA topoisomerase I [Roseovarius sp. TM1035].	26.89	331	191	10	1	312	1	299	2e-13	84.3
rs:XP_008076085	Prokaryotic type I DNA topoisomerase [Glarea lozoyensis ATCC 20868].	21.71	668	399	22	3	579	6	640	2e-13	84.0
tr:A0A0E0NET6_ORYRU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ORUFI02G17070.2};	23.09	628	373	27	39	610	261	834	2e-13	84.3
rs:WP_046401192	DNA topoisomerase I [Lactococcus garvieae].	24.55	558	353	22	103	630	109	628	2e-13	84.0
rs:WP_013015783	DNA topoisomerase I [Stackebrandtia nassauensis].	24.12	626	367	25	2	571	7	580	2e-13	84.3
rs:WP_044740086	DNA topoisomerase I [Bacillus mycoides].	23.52	489	276	17	187	629	213	649	2e-13	84.0
rs:WP_041035495	DNA topoisomerase I [Tolypothrix campylonemoides].	22.15	623	386	17	3	574	4	578	2e-13	84.0
rs:WP_031368295	hypothetical protein, partial [Clostridium botulinum].	33.00	203	101	5	457	652	81	255	2e-13	81.3
rs:WP_029330840	DNA topoisomerase I [Exiguobacterium oxidotolerans].	23.16	665	412	26	3	630	5	607	2e-13	84.0
rs:WP_018358151	hypothetical protein [Porphyromonas levii].	24.72	530	335	18	3	523	5	479	2e-13	84.0
rs:WP_033659367	DNA topoisomerase, partial [Enterococcus faecium].	31.91	141	91	4	3	139	5	144	2e-13	79.0
rs:WP_015506113	DNA topoisomerase I/SWI domain fusion protein [Chlamydia trachomatis].	22.53	679	415	26	3	630	5	623	2e-13	84.0
rs:WP_016581610	topoisomerase I, partial [Yersinia pestis].	23.32	596	363	19	74	630	86	626	2e-13	83.6
rs:WP_013727870	DNA topoisomerase I [Lactobacillus buchneri].	22.90	559	362	20	103	629	101	622	2e-13	84.0
tr:D4RDK4_ENTFC	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFF21997.1};	34.68	124	77	3	3	123	4	126	2e-13	79.0
rs:WP_029413081	DNA topoisomerase I [Acidobacteria bacterium JGI 0001001-H03].	24.32	555	331	20	3	532	5	495	2e-13	84.0
rs:WP_003713049	hypothetical protein, partial [Lactobacillus oris].	29.45	146	101	1	438	581	1	146	2e-13	80.9
rs:WP_003865910	DNA topoisomerase I [Holdemanella biformis].	24.30	642	395	23	3	614	5	585	2e-13	84.0
rs:XP_009886830	PREDICTED: DNA topoisomerase 3-alpha [Charadrius vociferus].	24.43	483	298	18	188	634	241	692	2e-13	84.3
rs:WP_010230372	DNA topoisomerase I [Gillisia marina].	26.68	461	291	16	74	521	51	477	2e-13	84.0
rs:XP_009311173	putative DNA topoisomerase III [Trypanosoma grayi].	22.32	596	361	23	46	596	8	546	2e-13	84.0
rs:WP_012496557	DNA topoisomerase I [Rhodopseudomonas palustris].	22.75	690	416	28	1	630	1	633	2e-13	84.0
rs:WP_014773067	DNA topoisomerase I [Belliella baltica].	27.50	400	237	14	3	392	5	361	2e-13	84.0
rs:XP_002280960	PREDICTED: uncharacterized protein LOC100247441 [Vitis vinifera].	23.31	635	400	28	32	610	396	999	2e-13	84.3
rs:WP_019189987	hypothetical protein [Clostridiales bacterium 9403326].	23.63	656	383	28	3	616	5	584	2e-13	83.6
gpu:CP011268_787	DNA topoisomerase 1 [candidate division SR1 bacterium Aalborg_AAW-1]	23.43	508	331	13	32	520	45	513	2e-13	84.0
rs:XP_007003116	hypothetical protein TREMEDRAFT_73248 [Tremella mesenterica DSM 1558].	23.94	660	383	32	3	598	4	608	2e-13	84.0
rs:XP_009516746	hypothetical protein PHYSODRAFT_470148 [Phytophthora sojae].	24.51	567	344	26	1	519	1	531	2e-13	84.0
rs:WP_009435473	DNA topoisomerase I [Prevotella sp. oral taxon 306].	23.76	606	364	23	3	580	5	540	2e-13	84.0
rs:WP_022317494	MULTISPECIES: DNA topoisomerase [Prevotella].	23.94	639	372	25	3	604	5	566	2e-13	84.0
rs:WP_036593777	DNA topoisomerase I, partial [Paenibacillus sophorae].	26.27	373	210	13	187	533	211	544	3e-13	84.0
tr:A0A0A0AQJ5_CHAVO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.43	483	298	18	188	634	221	672	3e-13	84.0
tr:A0A094NN34_9AVES	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.43	483	298	18	188	634	221	672	3e-13	84.0
rs:WP_044542577	DNA topoisomerase I [Bradyrhizobium sp. LTSP885].	22.85	687	418	28	1	630	1	632	3e-13	84.0
tr:A0A093PF87_PYGAD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.06	478	297	15	188	631	221	666	3e-13	84.0
rs:WP_045048085	hypothetical protein [Rouxiella chamberiensis].	36.61	112	61	4	1	108	1	106	3e-13	78.2
rs:XP_006637312	PREDICTED: DNA topoisomerase 3-alpha-like [Lepisosteus oculatus].	23.52	472	281	14	188	619	245	676	3e-13	84.0
tr:J9D679_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJX08236.1};	32.43	185	91	7	479	630	1	184	3e-13	79.7
rs:WP_025724508	DNA topoisomerase I [Acholeplasma granularum].	24.47	662	388	25	2	629	4	587	3e-13	83.6
tr:A0A0D3F546_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OBART02G16520.2};	22.97	640	383	28	39	610	251	848	3e-13	84.0
tr:W1F122_ECOLX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CDL27510.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDL27510.1};	32.93	167	104	3	468	629	8	171	3e-13	80.1
rs:WP_017258991	DNA topoisomerase I [Pedobacter arcticus].	24.95	525	333	17	74	578	51	534	3e-13	84.0
rs:WP_040152282	DNA topoisomerase III, partial [Xanthomonas citri].	30.22	182	113	4	437	611	40	214	3e-13	80.5
rs:XP_007158787	hypothetical protein PHAVU_002G181900g [Phaseolus vulgaris].	24.10	585	377	23	77	610	299	867	3e-13	84.0
rs:XP_008546120	PREDICTED: DNA topoisomerase 3-beta-1 [Microplitis demolitor].	22.35	434	284	12	188	601	210	610	3e-13	84.0
rs:WP_013836048	DNA topoisomerase I [Thioalkalimicrobium cyclicum].	24.69	405	248	10	3	392	4	366	3e-13	84.0
tr:T1C850_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD78317.1}; Flags: Fragment;	24.39	246	169	6	193	426	1	241	3e-13	80.5
rs:WP_042726447	DNA topoisomerase I, partial [Curtobacterium sp. B8].	23.77	589	339	20	2	528	11	551	3e-13	83.6
rs:WP_005814152	DNA topoisomerase I [Bacteroides fragilis].	23.27	623	382	25	3	604	5	552	3e-13	84.0
rs:WP_005856589	DNA topoisomerase I [Sagittula stellata].	22.93	593	340	22	1	534	1	535	3e-13	84.0
rs:WP_032734728	DNA topoisomerase I [Klebsiella oxytoca].	22.28	570	370	19	90	631	65	589	3e-13	83.6
tr:M6CI84_LEPME	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EMJ85945.1};	23.33	463	298	10	162	596	39	472	3e-13	83.2
rs:WP_021214322	DNA topoisomerase I, partial [Lactococcus lactis].	24.50	404	248	15	249	629	17	386	3e-13	83.2
rs:WP_013221847	DNA topoisomerase I [Nitrosococcus watsonii].	22.24	661	405	26	3	610	5	609	3e-13	84.0
rs:WP_042735212	DNA topoisomerase I [Lachnospiraceae bacterium TWA4].	23.45	452	288	13	187	614	161	578	3e-13	83.6
rs:WP_003560399	DNA topoisomerase I [Lactobacillus buchneri].	23.74	556	361	20	103	629	103	624	3e-13	83.6
rs:WP_019025494	MULTISPECIES: hypothetical protein [Thioalkalivibrio].	21.60	648	409	23	1	614	1	583	3e-13	83.6
rs:WP_013380804	DNA topoisomerase I [Eubacterium limosum].	22.70	674	424	22	3	639	5	618	3e-13	83.6
tr:A0A091UJS7_PHORB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.43	483	298	18	188	634	221	672	3e-13	84.0
tr:A0A0D6ME44_9GAMM	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAN45028.1};	23.78	471	299	14	103	538	80	525	3e-13	84.0
rs:WP_042894703	DNA topoisomerase I [Acinetobacter oleivorans].	23.32	579	357	18	90	629	116	646	3e-13	84.0
rs:WP_026624475	DNA topoisomerase I [Eggerthia catenaformis].	22.96	662	407	23	3	629	4	597	3e-13	83.6
rs:XP_009327672	PREDICTED: DNA topoisomerase 3-alpha [Pygoscelis adeliae].	24.06	478	297	15	188	631	241	686	3e-13	84.0
rs:WP_038351417	DNA topoisomerase I [Eubacterium limosum].	22.86	678	418	24	3	639	5	618	3e-13	83.6
rs:WP_028950752	DNA topoisomerase I [Sulfurihydrogenibium subterraneum].	24.20	653	402	22	55	659	28	635	3e-13	83.6
rs:WP_003602230	DNA topoisomerase I [Lactobacillus casei].	23.91	573	370	18	90	629	68	607	3e-13	83.6
rs:WP_004794819	DNA topoisomerase I [Acinetobacter sp. NIPH 817].	22.65	574	367	16	90	629	116	646	3e-13	84.0
rs:WP_016292372	DNA topoisomerase III [Lachnospiraceae bacterium 28-4].	36.28	113	56	4	2	107	5	108	3e-13	77.8
tr:W4YW04_STRPU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.12	406	260	12	188	579	212	587	3e-13	83.6
rs:WP_022661992	DNA topoisomerase I [Desulfovibrio longus].	23.36	595	374	18	76	631	53	604	3e-13	84.0
tr:L2HBN5_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELA53336.1};	31.76	148	87	4	3	141	4	146	3e-13	79.0
tr:T0ZRV5_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD47393.1}; Flags: Fragment;	31.58	152	91	2	189	328	3	153	3e-13	79.3
tr:A0A091VA01_NIPNI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.43	483	298	18	188	634	221	672	3e-13	84.0
rs:WP_034303372	DNA topoisomerase I [Alkalibacterium sp. AK22].	23.10	671	399	22	3	629	6	603	3e-13	83.6
rs:WP_007566173	DNA topoisomerase I [Methylobacterium sp. GXF4].	22.75	690	413	28	1	629	1	631	3e-13	84.0
rs:WP_013569613	DNA topoisomerase [Terriglobus saanensis].	23.74	577	353	18	97	616	75	621	3e-13	84.0
rs:WP_039784659	hypothetical protein, partial [Ancylobacter sp. FA202].	24.49	396	242	16	3	369	4	371	3e-13	82.8
rs:WP_008936803	MULTISPECIES: DNA topoisomerase I [Brucella].	22.61	690	415	29	1	629	1	632	3e-13	84.0
tr:F9VDX9_LACGL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.33	559	353	23	103	630	130	649	3e-13	83.6
rs:WP_041859254	hypothetical protein, partial [Candidatus Solibacter usitatus].	24.28	486	319	13	76	533	53	517	3e-13	84.0
rs:WP_017196441	DNA topoisomerase I [Bartonella birtlesii].	23.55	692	407	28	1	629	1	633	3e-13	84.0
rs:XP_010300310	PREDICTED: DNA topoisomerase 3-alpha [Balearica regulorum gibbericeps].	24.43	483	298	18	188	634	241	692	3e-13	84.0
rs:XP_010170981	PREDICTED: DNA topoisomerase 3-alpha [Caprimulgus carolinensis].	24.43	483	298	18	188	634	241	692	3e-13	84.0
rs:WP_015399038	DNA topoisomerase I [Bartonella vinsonii].	23.91	690	407	29	1	629	1	633	3e-13	84.0
rs:XP_011465095	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Fragaria vesca subsp. vesca].	23.09	641	386	25	3	585	5	596	3e-13	84.0
rs:WP_029939487	DNA topoisomerase I [Thiomicrospira sp. MA2-6].	22.98	531	339	16	3	520	4	477	3e-13	83.6
rs:WP_003853868	MULTISPECIES: topoisomerase I [Pantoea].	22.45	597	384	22	75	633	88	643	3e-13	84.0
rs:XP_012287250	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Orussus abietinus].	23.20	651	388	25	46	634	98	698	3e-13	84.0
tr:K1QMX0_CRAGI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.82	561	366	18	46	577	8	530	3e-13	84.3
rs:WP_041768668	DNA topoisomerase I [Pseudovibrio sp. FO-BEG1].	23.22	577	340	18	1	534	1	517	3e-13	84.0
rs:WP_007592026	DNA topoisomerase I [Lachnoanaerobaculum sp. OBRC5-5].	22.86	560	363	14	90	616	67	590	3e-13	83.6
rs:WP_027404227	DNA topoisomerase I [Aphanizomenon flos-aquae].	24.91	586	343	23	79	610	59	601	3e-13	83.6
rs:XP_011455652	PREDICTED: DNA topoisomerase 3-alpha-like isoform X2 [Crassostrea gigas].	22.82	561	366	18	46	577	8	530	3e-13	84.0
rs:XP_004289288	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Fragaria vesca subsp. vesca].	23.09	641	386	25	3	585	5	596	3e-13	84.0
rs:WP_011710863	DNA topoisomerase I [Gramella forsetii].	27.48	444	271	18	93	521	70	477	3e-13	83.6
rs:WP_014904444	DNA topoisomerase I [Desulfosporosinus meridiei].	23.01	591	374	22	88	634	62	615	3e-13	83.6
tr:A0A0A9WRY3_LYGHE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.29	560	348	23	46	573	91	606	3e-13	84.0
rs:WP_027837687	DNA topoisomerase I [Mastigocoleus testarum].	23.01	691	408	29	1	629	2	630	3e-13	84.0
rs:WP_022513709	DNA topoisomerase [Dialister sp. CAG:588].	22.64	592	364	22	88	629	94	641	3e-13	83.6
rs:WP_043805158	hypothetical protein, partial [Deinococcus gobiensis].	24.28	416	261	10	189	574	173	564	3e-13	83.2
rs:WP_045982897	DNA topoisomerase I [Paracoccus sp. S4493].	21.42	705	432	25	1	630	1	658	3e-13	84.0
rs:WP_009736670	DNA topoisomerase I [Bradyrhizobiaceae bacterium SG-6C].	24.46	691	403	33	1	630	1	633	3e-13	84.0
tr:W1PCV0_AMBTC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.23	520	315	21	64	536	411	898	3e-13	84.0
rs:WP_031860267	DNA topoisomerase III, partial [Staphylococcus aureus].	35.76	151	84	5	3	148	4	146	3e-13	79.0
rs:WP_008993939	DNA topoisomerase I [Novosphingobium sp. Rr 2-17].	21.75	676	422	23	1	629	1	616	3e-13	83.6
tr:W6I3A9_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.61	634	412	23	55	630	39	645	3e-13	84.0
tr:E5B5W3_ERWAM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.32	596	380	19	77	633	83	634	3e-13	83.6
rs:WP_004157737	topoisomerase I [Erwinia amylovora].	22.32	596	380	19	77	633	83	634	3e-13	83.6
rs:WP_039190177	DNA topoisomerase I [Aureimonas altamirensis].	22.66	715	416	31	1	643	1	650	3e-13	83.6
rs:XP_006844098	PREDICTED: uncharacterized protein LOC18433959 [Amborella trichopoda].	24.23	520	315	21	64	536	418	905	3e-13	84.0
rs:WP_008770105	MULTISPECIES: DNA topoisomerase I [Bacteroides].	24.76	626	369	29	3	604	5	552	3e-13	83.6
rs:WP_040126343	DNA topoisomerase I [Campylobacter fetus].	24.21	537	326	20	100	590	72	573	3e-13	83.2
tr:F0WXN3_9STRA	RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};	24.27	478	292	15	172	616	226	666	3e-13	84.3
tr:A0A0E0G6J7_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA02G17860.3};	23.09	628	373	27	39	610	308	881	3e-13	84.0
tr:A0A087V368_BALRE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.64	483	297	19	188	634	221	672	3e-13	84.0
rs:WP_022382153	DNA topoisomerase [Dialister sp. CAG:357].	23.76	665	407	24	3	629	36	638	3e-13	83.6
rs:WP_004561483	DNA topoisomerase I [Lactobacillus hilgardii].	23.74	556	361	20	103	629	103	624	3e-13	83.6
rs:XP_005145100	PREDICTED: DNA topoisomerase 3-alpha [Melopsittacus undulatus].	23.59	479	307	16	188	634	241	692	3e-13	84.0
rs:WP_028283498	DNA topoisomerase I [Olleya marilimosa].	24.58	533	328	18	3	521	5	477	3e-13	83.6
rs:WP_044589223	DNA topoisomerase I [Bradyrhizobium sp. LTSPM299].	22.71	687	419	27	1	630	1	632	3e-13	83.6
rs:WP_004904017	DNA topoisomerase I [Leuconostoc citreum].	22.68	560	366	20	88	616	84	607	3e-13	83.6
rs:WP_026598814	DNA topoisomerase I [Methylocystis sp. LW5].	23.16	652	401	28	38	630	22	632	3e-13	83.6
rs:WP_036642054	DNA topoisomerase I [Paenibacillus sp. FSL R5-808].	23.68	570	365	24	103	636	80	615	3e-13	83.6
tr:A0A0C6FPS9_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.77	685	419	26	1	629	1	631	3e-13	83.6
rs:WP_014024778	DNA topoisomerase I [Lactococcus garvieae].	24.37	558	354	22	103	630	109	628	3e-13	83.6
rs:WP_047002751	DNA topoisomerase I [Erythrobacter sp. KA37].	21.35	712	451	23	1	666	1	649	3e-13	83.6
gp:CP003182_2455	DNA topoisomerase I [Granulibacter bethesdensis CGDNIH4]	21.61	634	412	23	55	630	39	645	3e-13	83.6
rs:XP_001746649	hypothetical protein [Monosiga brevicollis MX1].	20.83	624	380	18	3	564	7	578	3e-13	84.0
rs:WP_010993765	DNA topoisomerase I [Bacteroides fragilis].	24.76	626	369	29	3	604	5	552	3e-13	83.6
tr:K1Z1A0_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.13	670	411	25	2	631	3	608	3e-13	83.2
rs:WP_005302100	DNA topoisomerase I [Acinetobacter sp. NIPH 542].	22.65	574	367	16	90	629	116	646	3e-13	83.6
gpu:CP009503_1228	DNA topoisomerase I [Methanosarcina sp. WWM596]	22.07	648	410	24	11	611	54	653	3e-13	83.6
rs:XP_005229069	PREDICTED: DNA topoisomerase 3-alpha [Falco peregrinus].	23.75	480	305	16	188	634	241	692	3e-13	83.6
rs:WP_035801076	DNA topoisomerase I [Butyrivibrio sp. FCS014].	22.86	560	363	19	90	616	63	586	3e-13	83.2
rs:WP_035221505	DNA topoisomerase, partial [Acidobacteriaceae bacterium KBS 83].	24.49	633	393	27	55	629	29	634	3e-13	83.6
rs:WP_035612931	DNA topoisomerase I [Hyphomonas johnsonii].	23.31	682	414	29	1	629	1	626	3e-13	83.6
rs:WP_016563078	DNA topoisomerase [Bacteroides sp. CAG:927].	25.16	465	297	16	77	526	53	481	3e-13	83.6
rs:WP_009218704	DNA topoisomerase I [Lachnospiraceae oral taxon 107].	23.32	566	352	18	90	616	67	589	3e-13	83.2
rs:WP_010665160	DNA topoisomerase I [Marinilabilia salmonicolor].	22.49	627	384	18	3	600	12	565	3e-13	83.6
rs:WP_015398003	DNA topoisomerase I [Bartonella australis].	22.24	697	410	29	1	629	1	633	3e-13	83.6
tr:A0A0A3W6Y3_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.00	475	291	16	187	629	188	624	3e-13	83.6
tr:T0ZSF8_9ZZZZ	SubName: Full=DNA topoisomerase III beta {ECO:0000313|EMBL:EQD51221.1}; Flags: Fragment;	28.30	318	186	11	101	395	104	402	3e-13	82.4
tr:H5T9E7_9ALTE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.45	708	391	28	3	629	5	642	3e-13	83.6
rs:WP_025718462	DNA topoisomerase I [Paenibacillus sp. 1-18].	22.61	566	376	20	103	636	80	615	3e-13	83.2
tr:F0WXN2_9STRA	RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};	24.27	478	292	15	172	616	226	666	3e-13	84.0
rs:WP_040520241	DNA topoisomerase I, partial [Glaciecola punicea].	24.51	608	351	23	76	629	89	642	3e-13	83.6
tr:A0A0D9WP91_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:LPERR06G09500.1};	22.70	652	394	27	39	628	328	931	3e-13	83.6
rs:WP_042988647	MULTISPECIES: hypothetical protein [Vibrio].	22.66	653	379	25	1	614	1	566	3e-13	83.2
rs:WP_031883535	DNA topoisomerase III, partial [Staphylococcus aureus].	34.15	164	95	5	3	161	4	159	3e-13	79.0
tr:B6FZ87_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.04	619	353	25	103	671	87	644	3e-13	83.2
rs:WP_013932339	reverse gyrase [Pseudothermotoga thermarum].	24.21	537	308	20	78	581	687	1157	3e-13	83.6
rs:WP_031921357	DNA topoisomerase III, partial [Staphylococcus aureus].	37.41	139	74	5	3	136	4	134	4e-13	78.6
tr:A0A0C1R6M7_9CYAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.59	585	352	20	79	610	59	601	4e-13	83.2
tr:V8AUH0_9LACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.37	558	354	22	103	630	109	628	4e-13	83.2
rs:WP_025286316	DNA topoisomerase I [Granulibacter bethesdensis].	21.61	634	412	23	55	630	28	634	4e-13	83.6
rs:WP_036255616	DNA topoisomerase I [Methylocapsa acidiphila].	23.09	719	432	28	1	661	1	656	4e-13	83.6
rs:WP_004781880	DNA topoisomerase I [Acinetobacter sp. NIPH 899].	24.21	475	290	15	187	629	212	648	4e-13	83.6
tr:A0A0B7A9N8_9EUPU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.31	459	310	15	3	429	5	453	4e-13	82.4
gpu:CP009515_2176	DNA topoisomerase I [Methanosarcina lacustris Z-7289]	22.34	640	397	24	21	611	27	615	4e-13	83.6
rs:WP_040410425	DNA topoisomerase I [[Clostridium] hiranonis].	25.04	619	353	25	103	671	81	638	4e-13	83.2
tr:F0WXN9_9STRA	RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};	24.27	478	292	15	172	616	226	666	4e-13	84.0
rs:WP_009505253	DNA topoisomerase I [Citreicella sp. 357].	22.58	598	346	20	1	534	1	545	4e-13	83.6
rs:WP_034335979	hypothetical protein, partial [Deinococcus misasensis].	23.16	626	368	27	1	574	1	565	4e-13	83.2
rs:WP_046200490	DNA topoisomerase I [Porphyromonas gulae].	23.68	532	335	16	3	520	4	478	4e-13	83.6
rs:WP_015799301	DNA topoisomerase I [Acidimicrobium ferrooxidans].	22.68	529	290	17	77	538	68	544	4e-13	83.6
rs:WP_044300295	DNA topoisomerase I [Bacteroides fragilis].	23.89	628	372	27	3	604	5	552	4e-13	83.6
rs:XP_012287248	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Orussus abietinus].	23.20	651	388	25	46	634	98	698	4e-13	83.6
rs:WP_032963408	DNA topoisomerase I [Lactobacillus rhamnosus].	22.74	576	373	16	90	629	68	607	4e-13	83.2
tr:V9TUY8_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.99	617	374	25	2	577	3	565	4e-13	83.6
rs:WP_004285114	DNA topoisomerase I [Neisseria weaveri].	21.38	725	466	24	3	679	5	673	4e-13	83.2
rs:WP_013337555	DNA topoisomerase [Vulcanisaeta distributa].	21.32	605	403	19	3	571	6	573	4e-13	83.2
rs:XP_012287249	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Orussus abietinus].	23.20	651	388	25	46	634	98	698	4e-13	83.6
rs:WP_042366602	DNA topoisomerase I [Bacteroidaceae bacterium MS4].	22.65	618	386	21	3	595	5	555	4e-13	83.2
rs:WP_036497849	DNA topoisomerase I [Mycoplasma yeatsii].	23.20	638	405	23	3	610	4	586	4e-13	83.2
tr:H8H3H1_DEIGI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.28	416	261	10	189	574	173	564	4e-13	83.2
tr:F0WXN5_9STRA	RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};	24.27	478	292	15	172	616	226	666	4e-13	84.0
gpu:CP009967_6	DNA topoisomerase family protein [Bacillus cereus E33L]	29.41	238	130	10	1	209	1	229	4e-13	80.1
rs:WP_002332999	MULTISPECIES: hypothetical protein [Enterococcus].	37.07	116	61	3	3	111	4	114	4e-13	77.8
rs:WP_036420687	DNA topoisomerase III, partial [Morganella morganii].	29.69	229	140	5	462	676	9	230	4e-13	80.1
rs:WP_042492497	DNA topoisomerase I [Weissella hellenica].	22.21	662	417	24	3	629	36	634	4e-13	83.2
rs:WP_017950657	MULTISPECIES: hypothetical protein [Marinimicrobia].	22.90	594	384	16	76	629	53	612	4e-13	83.2
rs:WP_041093558	DNA topoisomerase I [Lactobacillus hokkaidonensis].	23.90	569	370	21	90	629	88	622	4e-13	83.2
rs:WP_005781823	DNA topoisomerase I [Bacteroides fragilis].	23.89	628	372	27	3	604	5	552	4e-13	83.2
rs:WP_014021586	DNA topoisomerase I [Cyclobacterium marinum].	24.95	537	321	19	3	520	5	478	4e-13	83.2
rs:WP_004763747	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	23.01	578	360	18	90	629	117	647	4e-13	83.6
rs:WP_018910698	DNA topoisomerase I [Prevotella veroralis].	23.39	607	365	21	3	580	5	540	4e-13	83.2
rs:WP_024278932	DNA topoisomerase I [Xanthobacter sp. 126].	22.53	697	409	29	1	630	1	633	4e-13	83.6
tr:C9YD02_9BURK	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:CBA30889.1};	35.46	141	80	5	3	135	20	157	4e-13	83.2
tr:A0A094LFW4_ANTCR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.43	483	298	18	188	634	221	672	4e-13	83.6
rs:XP_010211313	PREDICTED: DNA topoisomerase 3-alpha [Tinamus guttatus].	24.12	481	302	17	188	634	241	692	4e-13	83.2
rs:WP_045721025	DNA topoisomerase III, partial [Salmonella enterica].	35.09	114	64	4	1	110	1	108	4e-13	77.4
rs:WP_035526289	DNA topoisomerase I [Hoeflea sp. BAL378].	22.29	700	411	27	1	630	1	637	4e-13	83.6
tr:I1G5R1_AMPQE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.71	348	219	9	163	493	144	465	4e-13	83.2
rs:WP_028325750	DNA topoisomerase I [Desulfatirhabdium butyrativorans].	24.41	598	362	23	90	639	67	622	4e-13	83.2
rs:WP_004803752	DNA topoisomerase I [Eggerthia catenaformis].	22.96	662	407	23	3	629	4	597	4e-13	83.2
rs:XP_010320983	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Solanum lycopersicum].	23.54	497	302	18	127	592	78	527	4e-13	83.2
rs:WP_026990473	DNA topoisomerase I [Flavobacterium subsaxonicum].	23.96	530	335	17	3	521	5	477	4e-13	83.2
rs:WP_029444934	DNA topoisomerase I [Cellulophaga baltica].	24.91	530	332	16	3	521	5	479	4e-13	83.2
rs:NP_001025807	DNA topoisomerase 3-alpha isoform 1 [Gallus gallus].	24.79	484	295	18	188	634	241	692	4e-13	83.6
rs:WP_007209321	topoisomerase [Enterococcus italicus].	37.07	116	61	3	3	111	4	114	4e-13	77.8
rs:XP_008497098	PREDICTED: DNA topoisomerase 3-alpha [Calypte anna].	24.59	484	296	19	188	634	241	692	4e-13	83.6
rs:WP_006450818	topoisomerase IA, partial [Xanthomonas gardneri].	27.62	239	160	6	276	501	8	246	4e-13	80.1
rs:XP_009666302	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Struthio camelus australis].	23.40	483	303	16	188	634	241	692	4e-13	83.6
rs:WP_016275131	DNA topoisomerase I [Bacteroides massiliensis].	24.78	561	353	19	77	617	54	565	4e-13	83.2
tr:A0A072NXV4_9EURO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.73	462	286	13	163	584	11	441	4e-13	82.4
rs:WP_002349461	toprim domain protein, partial [Enterococcus faecium].	31.91	141	91	4	3	139	4	143	4e-13	78.6
rs:WP_033801726	DNA topoisomerase III, partial [Escherichia coli].	30.36	224	135	5	467	676	2	218	4e-13	79.7
rs:WP_012194987	DNA topoisomerase I [Prochlorococcus marinus].	23.06	607	381	19	3	566	5	568	4e-13	83.2
rs:WP_031880389	DNA topoisomerase III, partial [Staphylococcus aureus].	35.76	151	84	5	3	148	4	146	4e-13	78.6
tr:S6G6V6_9MOLU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00003390}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.20	638	405	23	3	610	6	588	4e-13	82.8
rs:WP_010125844	DNA topoisomerase I [Sphingomonas sp. KC8].	21.75	685	421	24	1	629	1	626	4e-13	83.2
rs:WP_025320889	DNA topoisomerase I [Granulibacter bethesdensis].	21.61	634	412	23	55	630	28	634	4e-13	83.2
rs:WP_024880185	DNA topoisomerase I [Methylosinus sp. LW3].	23.11	649	405	26	38	630	22	632	4e-13	83.6
rs:WP_034459248	DNA topoisomerase I [Bartonella koehlerae].	23.62	690	409	29	1	629	1	633	4e-13	83.2
tr:U4U7I5_DENPD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.67	397	253	12	188	564	168	530	4e-13	83.2
rs:WP_031878374	DNA topoisomerase III, partial [Staphylococcus aureus].	35.76	151	84	5	3	148	4	146	4e-13	78.6
rs:WP_006801926	DNA topoisomerase I [Helicobacter winghamensis].	22.69	661	414	24	3	629	4	601	4e-13	83.2
rs:WP_009809315	DNA topoisomerase I [Roseobacter sp. MED193].	22.68	701	413	31	1	630	1	643	4e-13	83.2
rs:WP_004056034	hypothetical protein [Eubacterium plexicaudatum].	34.62	104	54	3	1	99	1	95	4e-13	77.4
rs:WP_039420547	DNA topoisomerase I [Porphyromonas gulae].	23.87	532	334	16	3	520	4	478	4e-13	83.2
rs:WP_015325136	topoisomerase IA [Methanomethylovorans hollandica].	22.76	558	371	17	88	614	103	631	4e-13	83.2
rs:WP_036796725	DNA topoisomerase I [Porphyrobacter sp. HL-46].	21.44	681	421	25	1	629	1	619	4e-13	83.2
rs:WP_004029070	DNA topoisomerase I [Spiroplasma melliferum].	24.65	637	393	24	38	643	24	604	4e-13	82.8
rs:WP_025124920	DNA topoisomerase I [Myroides odoratimimus].	25.56	536	319	20	3	521	5	477	4e-13	83.2
rs:WP_008184655	DNA topoisomerase I [Rhodobacteraceae bacterium HTCC2150].	22.45	686	411	29	1	629	1	622	4e-13	83.2
tr:F3FB74_PSEA0	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGH27460.1}; Flags: Fragment;	28.27	191	104	6	1	177	1	172	4e-13	79.0
rs:WP_027522980	DNA topoisomerase I [Bradyrhizobium sp. Ec3.3].	23.69	688	411	29	1	630	1	632	4e-13	83.2
rs:WP_011520484	topoisomerase I [Candidatus Baumannia cicadellinicola].	23.06	477	316	13	188	649	180	620	4e-13	83.2
rs:WP_003553968	DNA topoisomerase I [Lactobacillus brevis].	23.74	556	361	20	103	629	103	624	4e-13	83.2
rs:WP_009470741	topoisomerase I [gamma proteobacterium HIMB55].	22.85	477	314	12	76	533	93	534	4e-13	83.2
tr:A0A091IBC6_CALAN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.59	484	296	19	188	634	221	672	4e-13	83.2
rs:WP_041140988	DNA topoisomerase I [Sulfurovum sp. PC08-66].	22.67	666	408	22	3	629	4	601	4e-13	83.2
rs:WP_039020056	DNA topoisomerase I [Halocynthiibacter namhaensis].	22.71	568	344	21	1	534	1	507	4e-13	83.2
rs:WP_028345613	DNA topoisomerase I [Bradyrhizobium elkanii].	23.19	690	412	26	1	630	1	632	4e-13	83.2
rs:XP_002175891	DNA topoisomerase III [Schizosaccharomyces japonicus yFS275].	22.38	621	397	20	3	572	4	590	4e-13	82.8
rs:WP_012457773	DNA topoisomerase I [Porphyromonas gingivalis].	23.68	532	335	16	3	520	4	478	4e-13	83.2
rs:WP_003144692	DNA topoisomerase I [Gemella haemolysans].	24.49	584	346	23	90	629	69	601	4e-13	82.8
rs:WP_021296476	DNA topoisomerase I [Alicyclobacillus acidoterrestris].	24.25	569	348	26	88	615	62	588	4e-13	82.8
rs:WP_005605437	DNA topoisomerase I [Granulicatella adiacens].	24.00	575	366	24	90	630	68	605	4e-13	82.8
rs:WP_046976139	DNA topoisomerase I [Photorhabdus temperata].	22.95	623	349	23	75	633	79	634	4e-13	83.2
rs:WP_029081047	DNA topoisomerase I [Bradyrhizobium sp. th.b2].	22.71	687	419	27	1	630	1	632	4e-13	83.2
rs:WP_032821503	topoisomerase I, partial [Oenococcus oeni].	29.25	147	102	1	437	581	1	147	4e-13	80.1
rs:WP_012455374	DNA topoisomerase I [Methylobacterium populi].	22.29	691	415	27	1	629	1	631	4e-13	83.2
rs:WP_014356315	DNA topoisomerase I [Acetobacterium woodii].	23.00	587	376	21	90	639	67	614	4e-13	82.8
rs:WP_043670276	DNA topoisomerase I [Clavibacter michiganensis].	23.17	587	337	21	2	528	6	538	4e-13	83.2
rs:WP_011250042	endonuclease [Thermococcus kodakarensis].	25.68	331	208	11	3	310	4	319	4e-13	83.6
rs:WP_011250042	endonuclease [Thermococcus kodakarensis].	24.34	419	219	15	307	660	827	1212	3e-11	77.8
rs:WP_016876994	DNA topoisomerase I [Chlorogloeopsis fritschii].	22.17	618	395	16	3	574	4	581	5e-13	83.2
rs:WP_042217744	DNA topoisomerase I [Lactococcus garvieae].	24.37	558	354	22	103	630	109	628	5e-13	82.8
tr:F2PIT5_TRIEC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.23	620	374	25	3	560	6	585	5e-13	82.8
rs:WP_019269690	DNA topoisomerase I [Mycoplasma capricolum].	23.32	669	400	29	3	625	4	605	5e-13	82.8
tr:U7QC71_9CYAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.91	530	325	19	77	564	38	536	5e-13	83.2
rs:WP_018414164	DNA topoisomerase I [Candidatus Pelagibacter ubique].	22.84	696	401	31	1	629	1	627	5e-13	83.2
rs:WP_002642410	DNA topoisomerase I [Simonsiella muelleri].	22.28	579	369	17	76	611	53	593	5e-13	83.2
rs:YP_001654102	DNA topoisomerase I [Chlamydia trachomatis 434/Bu].	22.56	656	402	25	3	612	5	600	5e-13	83.2
rs:WP_008612038	DNA topoisomerase I [Joostella marina].	23.23	538	329	16	3	521	5	477	5e-13	83.2
rs:WP_032539136	DNA topoisomerase I [Bacteroides fragilis].	23.89	628	372	27	3	604	5	552	5e-13	83.2
tr:T0UGY1_LEUMC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.32	560	361	18	90	616	104	622	5e-13	82.8
rs:WP_010744647	DNA topoisomerase 1 [Enterococcus raffinosus].	24.06	586	366	24	90	635	68	614	5e-13	82.8
rs:XP_003738893	PREDICTED: DNA topoisomerase 3-alpha [Metaseiulus occidentalis].	23.21	655	402	31	19	622	37	641	5e-13	82.8
rs:WP_028653086	DNA topoisomerase I [Nocardioides halotolerans].	25.04	655	378	32	2	596	4	605	5e-13	83.2
rs:WP_042555596	DNA topoisomerase I [Pseudomonas fulva].	23.40	483	296	16	186	633	194	637	5e-13	83.2
rs:WP_028607340	DNA topoisomerase I [Olleya sp. VCSM12].	24.86	531	329	19	3	521	5	477	5e-13	83.2
rs:XP_009666303	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Struthio camelus australis].	23.40	483	303	16	188	634	163	614	5e-13	83.2
tr:D3BRX9_POLPA	RecName: Full=Ribose-phosphate pyrophosphokinase {ECO:0000256|RuleBase:RU004325}; EC=2.7.6.1 {ECO:0000256|RuleBase:RU004325};	22.11	665	426	24	1	612	328	953	5e-13	83.2
tr:V6DHF8_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.91	598	390	20	74	630	64	631	5e-13	82.8
rs:XP_002189800	PREDICTED: DNA topoisomerase 3-alpha [Taeniopygia guttata].	24.69	482	298	18	188	634	239	690	5e-13	83.2
rs:WP_044215064	DNA topoisomerase I, partial [Candidatus Endolissoclinum faulkneri].	23.99	617	374	25	2	577	3	565	5e-13	83.2
tr:F2S5G3_TRIT1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.14	618	377	24	3	560	6	585	5e-13	82.8
rs:WP_023074624	dna topoisomerase i [Leptolyngbya sp. Heron Island J].	24.52	416	245	12	187	560	173	561	5e-13	83.2
rs:WP_016843950	DNA topoisomerase I, partial [Bradyrhizobium elkanii].	22.82	688	417	27	1	630	1	632	5e-13	82.8
tr:T0E7I0_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.56	274	161	8	276	538	4	256	5e-13	80.1
rs:WP_042733568	DNA topoisomerase I [Mycoplasma yeatsii].	23.35	638	404	23	3	610	4	586	5e-13	82.8
rs:WP_042085044	DNA topoisomerase I [Acinetobacter bereziniae].	23.85	587	376	18	74	629	102	648	5e-13	83.2
rs:WP_010244475	MULTISPECIES: topoisomerase I [Pantoea].	23.22	603	372	24	75	633	88	643	5e-13	83.2
tr:W1HHS0_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	23.33	403	252	11	256	633	60	430	5e-13	82.8
rs:WP_010761353	DNA topoisomerase 1 [Enterococcus haemoperoxidus].	24.82	560	354	20	103	629	81	606	5e-13	82.8
rs:WP_012246114	DNA topoisomerase I [Renibacterium salmoninarum].	23.46	584	342	20	2	530	15	548	5e-13	83.2
tr:A0A093H5G5_STRCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.60	483	302	17	188	634	221	672	5e-13	83.2
tr:D3AV32_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EFC94324.1}; Flags: Fragment;	26.19	252	166	6	356	593	1	246	5e-13	79.7
rs:WP_033757842	DNA topoisomerase I [Pantoea agglomerans].	23.22	603	372	24	75	633	88	643	5e-13	83.2
rs:WP_038254792	DNA topoisomerase I [Xenorhabdus bovienii].	23.92	485	291	17	187	633	188	632	5e-13	83.2
rs:WP_015849264	endonuclease [Thermococcus sibiricus].	26.23	385	209	10	307	640	827	1187	5e-13	83.2
rs:WP_015849264	endonuclease [Thermococcus sibiricus].	24.47	331	212	10	3	310	4	319	8e-12	79.3
rs:WP_034585104	DNA topoisomerase I [Acinetobacter sp. HR7].	24.00	475	291	16	187	629	212	648	5e-13	83.2
tr:D7WI61_BACCE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFI65101.1};	30.59	170	106	4	432	590	19	187	5e-13	79.0
rs:WP_044601245	hypothetical protein [Candidatus Babela massiliensis].	22.91	598	390	20	74	630	51	618	5e-13	82.8
rs:WP_008629835	DNA topoisomerase I [Mariniradius saccharolyticus].	25.94	397	247	11	3	392	5	361	5e-13	82.8
rs:WP_027306991	DNA topoisomerase I [Candidatus Pelagibacter ubique].	23.45	695	398	32	1	629	1	627	5e-13	82.8
rs:WP_012263525	DNA topoisomerase I [Chlamydia trachomatis].	22.37	684	410	27	3	630	5	623	5e-13	82.8
rs:WP_020857203	DNA topoisomerase I [SAR86 cluster bacterium SAR86A].	22.97	640	409	24	75	680	87	676	5e-13	82.8
rs:WP_034169866	DNA topoisomerase I [Acinetobacter sp. YZS-X1-1].	24.00	475	291	15	187	629	212	648	5e-13	82.8
rs:WP_037317256	DNA topoisomerase I [Salegentibacter sp. Hel_I_6].	24.16	538	326	20	3	521	5	479	5e-13	82.8
rs:WP_005998667	DNA topoisomerase I [Desulfuromonas acetoxidans].	23.99	521	313	20	157	630	136	620	5e-13	82.8
tr:M0REU8_MUSAM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.38	509	316	18	75	536	19	500	5e-13	82.8
rs:WP_023045298	topoisomerase I [Photorhabdus temperata].	22.95	623	349	23	75	633	79	634	5e-13	82.8
rs:WP_032492066	DNA topoisomerase III, partial [Vibrio cholerae].	27.88	165	111	2	457	614	1	164	5e-13	79.7
rs:WP_034558163	DNA topoisomerase I [Helicobacter muridarum].	22.34	658	385	26	52	629	21	632	5e-13	82.8
tr:F1P1F3_CHICK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.59	484	296	18	188	634	241	692	5e-13	83.2
rs:WP_008151621	hypothetical protein, partial [Parabacteroides johnsonii].	36.72	128	64	3	1	117	1	122	5e-13	78.2
tr:A4MY78_HAEIF	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EDJ88970.1};	31.54	149	91	5	1	144	1	143	5e-13	78.2
rs:WP_000513606	hypothetical protein, partial [Escherichia coli].	24.39	488	304	20	73	533	74	523	5e-13	82.4
rs:WP_011062924	DNA topoisomerase I [Pseudomonas protegens].	22.74	576	375	16	77	619	62	600	5e-13	82.4
rs:WP_041173544	DNA topoisomerase I [Clostridium botulinum].	25.72	661	367	28	3	616	5	588	5e-13	82.8
rs:WP_010829322	hypothetical protein, partial [Enterococcus faecalis].	39.47	114	65	3	3	113	4	116	6e-13	77.4
rs:WP_033787708	DNA topoisomerase I [Pantoea agglomerans].	23.22	603	372	24	75	633	88	643	6e-13	82.8
tr:J5L2K4_PASMD	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJS90469.1};	38.78	98	60	0	486	583	8	105	6e-13	77.8
tr:G4NN22_CHLT4	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.56	656	402	25	3	612	18	613	6e-13	82.8
rs:WP_026120863	DNA topoisomerase I [Nocardiopsis potens].	24.07	590	333	22	2	530	24	559	6e-13	82.8
rs:WP_041289732	DNA topoisomerase I [Kribbella flavida].	22.71	656	388	24	4	591	1	605	6e-13	82.8
rs:WP_023853733	DNA topoisomerase I [Candidatus Pelagibacter ubique].	21.87	686	420	24	1	629	1	627	6e-13	82.8
rs:WP_019959258	DNA topoisomerase I [Vitreoscilla stercoraria].	22.14	673	417	21	3	630	5	615	6e-13	82.8
rs:WP_022008889	DNA topoisomerase [Firmicutes bacterium CAG:646].	22.20	617	369	21	90	630	67	648	6e-13	82.8
rs:WP_002604312	DNA topoisomerase I [[Clostridium] hathewayi].	24.21	570	344	22	90	616	67	591	6e-13	82.8
rs:WP_042105386	DNA topoisomerase I [Parachlamydiaceae bacterium HS-T3].	23.20	681	405	25	3	630	5	620	6e-13	82.8
rs:WP_022822824	DNA topoisomerase I [Hymenobacter norwichensis].	22.45	548	341	15	3	526	5	492	6e-13	82.8
rs:WP_009872013	DNA topoisomerase I [Chlamydia trachomatis].	22.56	656	402	25	3	612	5	600	6e-13	82.8
rs:NP_220161	DNA topoisomerase I [Chlamydia trachomatis D/UW-3/CX].	22.56	656	402	25	3	612	5	600	6e-13	82.8
rs:WP_032825101	topoisomerase I, partial [Oenococcus oeni].	27.63	152	108	1	432	581	32	183	6e-13	79.7
rs:WP_040195133	DNA topoisomerase I [Clostridium sp. CL-6].	23.13	575	359	16	83	618	60	590	6e-13	82.8
rs:WP_026063933	DNA topoisomerase I [Lactococcus garvieae].	24.37	558	354	22	103	630	109	628	6e-13	82.8
rs:WP_035263470	DNA topoisomerase I, partial [Desulfonatronum lacustre].	22.58	651	414	25	76	679	53	660	6e-13	82.8
rs:XP_008659454	PREDICTED: uncharacterized protein LOC103638270 isoform X2 [Zea mays].	23.93	514	318	19	64	536	353	834	6e-13	83.2
rs:WP_016868952	hypothetical protein, partial [Fischerella muscicola].	25.34	580	349	22	79	610	59	602	6e-13	82.4
rs:XP_003601731	DNA topoisomerase [Medicago truncatula].	22.78	417	277	10	189	590	357	743	6e-13	82.8
rs:WP_009364289	DNA topoisomerase I [Brucella sp. BO2].	22.61	690	415	29	1	629	1	632	6e-13	82.8
rs:WP_009872811	DNA topoisomerase I [Chlamydia trachomatis].	22.14	655	406	24	3	612	5	600	6e-13	82.8
rs:WP_023566947	DNA topoisomerase I, partial [Escherichia coli].	23.20	444	281	16	256	673	22	431	6e-13	82.0
rs:WP_013468922	DNA topoisomerase I [Helicobacter felis].	22.85	674	388	25	2	614	6	608	6e-13	82.8
tr:H6RHI0_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.97	463	299	12	74	520	51	476	6e-13	82.8
tr:G5H1L9_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.27	583	401	15	83	636	30	583	6e-13	82.4
rs:WP_006045293	DNA topoisomerase I [Prevotella pallens].	22.20	599	382	17	3	580	24	559	6e-13	82.8
tr:U3KH13_FICAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.51	412	256	13	188	579	239	615	6e-13	82.8
rs:WP_029416389	DNA topoisomerase I [Brevundimonas bacteroides].	22.05	576	347	18	1	534	1	516	6e-13	82.8
tr:K2FS61_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.82	666	397	19	1	616	1	599	6e-13	82.8
tr:B1KWM7_CLOBM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.87	661	366	29	3	616	9	592	6e-13	82.4
rs:WP_002712162	DNA topoisomerase I [Afipia clevelandensis].	24.46	691	403	33	1	630	1	633	6e-13	82.8
tr:H0Z9W6_TAEGU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.69	482	298	18	188	634	223	674	6e-13	82.8
rs:XP_007727250	DNA topoisomerase III [Capronia coronata CBS 617.96].	22.64	636	400	24	3	584	7	604	6e-13	82.4
tr:Q5I6D5_TRYCR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.64	587	356	22	46	582	55	587	6e-13	82.8
rs:WP_031591590	DNA topoisomerase I [Pantoea agglomerans].	23.29	601	374	23	75	633	88	643	6e-13	82.8
rs:WP_018474198	DNA topoisomerase I [Echinicola pacifica].	24.11	535	329	16	3	520	5	479	6e-13	82.8
rs:WP_012175861	DNA topoisomerase I [Desulfococcus oleovorans].	24.00	625	401	27	39	629	25	609	6e-13	82.8
rs:XP_005054687	PREDICTED: DNA topoisomerase 3-alpha [Ficedula albicollis].	24.51	412	256	13	188	579	239	615	6e-13	82.8
rs:WP_040363681	DNA topoisomerase I [Commensalibacter intestini].	23.08	637	399	22	55	629	28	635	6e-13	82.8
rs:WP_042993550	DNA topoisomerase I, partial [Bordetella bronchiseptica].	23.25	456	288	13	90	520	65	483	6e-13	82.0
rs:WP_011839408	reverse gyrase [Staphylothermus marinus].	25.76	427	231	18	186	581	913	1284	6e-13	83.2
rs:WP_027581240	DNA topoisomerase I [Bradyrhizobium sp. Ai1a-2].	22.37	684	425	28	1	630	1	632	6e-13	82.8
tr:H4J7F7_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.39	488	304	20	73	533	74	523	6e-13	82.4
tr:F5TCL2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	24.43	479	295	18	186	630	6	451	6e-13	82.0
rs:WP_011679534	DNA topoisomerase I [Leuconostoc mesenteroides].	22.32	560	361	18	90	616	87	605	6e-13	82.4
rs:WP_004164241	DNA topoisomerase I [Leuconostoc mesenteroides].	22.32	560	361	18	90	616	87	605	6e-13	82.4
rs:WP_044061637	hypothetical protein, partial [Escherichia coli].	29.63	216	137	6	456	664	38	245	6e-13	79.3
rs:WP_025267939	DNA topoisomerase I [Leuconostoc mesenteroides].	22.32	560	361	18	90	616	87	605	6e-13	82.4
rs:WP_022100949	DNA topoisomerase I [Prevotella sp. CAG:5226].	24.26	404	247	10	3	391	5	364	6e-13	82.8
tr:A0A091ISF3_9AVES	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.22	483	299	18	188	634	221	672	6e-13	82.8
rs:WP_011307105	DNA topoisomerase [Methanosarcina barkeri].	23.68	587	340	23	90	611	92	635	6e-13	82.8
rs:WP_046201098	DNA topoisomerase I [Candidatus Pantoea carbekii].	21.78	574	385	18	90	633	93	632	6e-13	82.8
rs:WP_007657593	DNA topoisomerase I [Pontibacter sp. BAB1700].	21.86	613	395	18	3	596	5	552	6e-13	82.8
rs:WP_027327234	DNA topoisomerase I [Helicobacter pametensis].	24.80	512	305	15	55	529	28	496	6e-13	82.4
rs:WP_010853341	DNA topoisomerase I [Cyclobacteriaceae bacterium AK24].	25.42	531	327	19	3	520	5	479	6e-13	82.4
gpu:CP009524_2457	DNA topoisomerase I [Methanosarcina sp. Kolksee]	23.02	643	387	27	90	670	92	688	6e-13	82.8
rs:WP_013666437	DNA topoisomerase I [Sphingobacterium sp. 21].	23.26	546	325	19	3	520	5	484	6e-13	82.4
rs:WP_039427755	DNA topoisomerase I [Porphyromonas sp. COT-052 OH4946].	23.73	531	335	15	3	520	4	477	6e-13	82.4
rs:WP_016544013	DNA topoisomerase I [Leptospira wolffii].	23.52	625	380	24	55	630	28	603	6e-13	82.4
tr:A0A090SHM2_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL27225.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL27225.1};	36.21	116	64	4	2	113	3	112	6e-13	77.4
tr:G6EY22_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.47	605	375	21	84	629	18	593	7e-13	82.8
rs:XP_005647407	prokaryotic type I DNA topoisomerase [Coccomyxa subellipsoidea C-169].	21.96	624	404	23	3	585	9	590	7e-13	82.8
rs:WP_022544872	hypothetical protein [Bacteroidales bacterium CF].	23.93	535	331	18	3	520	5	480	7e-13	82.4
rs:WP_045960321	DNA topoisomerase I [Candidatus Liberibacter solanacearum].	23.57	666	399	26	1	612	1	610	7e-13	82.8
rs:XP_814477	DNA topoisomerase III [Trypanosoma cruzi strain CL Brener].	21.64	587	356	22	46	582	55	587	7e-13	82.8
tr:M0V3B5_HORVD	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:MLOC_17646.1};	23.06	373	244	10	258	614	14	359	7e-13	81.6
rs:WP_011580693	DNA topoisomerase I [Chelativorans sp. BNC1].	21.55	696	417	28	1	630	1	633	7e-13	82.8
rs:XP_009367981	PREDICTED: uncharacterized protein LOC103957527 isoform X2 [Pyrus x bretschneideri].	22.55	612	388	25	64	618	407	989	7e-13	82.8
rs:XP_001539853	DNA topoisomerase III [Histoplasma capsulatum NAm1].	21.89	644	403	21	3	586	6	609	7e-13	82.4
rs:WP_044227149	DNA topoisomerase I [Phaeodactylibacter xiamenensis].	22.69	498	323	16	3	480	5	460	7e-13	82.8
rs:WP_014299590	DNA topoisomerase I [Bacteroides fragilis].	24.60	626	370	29	3	604	5	552	7e-13	82.4
rs:WP_005035632	MULTISPECIES: topoisomerase I [Acinetobacter].	23.85	587	376	18	74	629	102	648	7e-13	82.8
rs:XP_007758610	DNA topoisomerase III [Cladophialophora yegresii CBS 114405].	22.67	547	340	17	82	584	97	604	7e-13	82.4
rs:WP_034411083	DNA topoisomerase I [Candidatus Photodesmus katoptron].	23.87	599	367	21	77	633	90	641	7e-13	82.8
rs:WP_025567135	DNA topoisomerase I [Gammaproteobacteria bacterium SCGC AAA003-E02].	22.94	632	412	19	77	673	94	685	7e-13	82.8
rs:WP_046713244	DNA topoisomerase I [Myxococcus fulvus].	22.97	627	381	27	76	640	131	717	7e-13	82.4
rs:XP_010390949	PREDICTED: DNA topoisomerase 3-alpha, partial [Corvus cornix cornix].	24.75	408	260	15	188	579	224	600	7e-13	82.8
tr:Q8SS31_ENCCU	SubName: Full=ECU04_1070 protein {ECO:0000313|EMBL:CAD25295.2};	22.39	603	390	19	3	573	4	560	7e-13	82.4
rs:WP_009117526	DNA topoisomerase I [Neisseria wadsworthii].	22.26	620	381	23	70	630	37	614	7e-13	82.4
rs:XP_010717866	PREDICTED: DNA topoisomerase 3-alpha [Meleagris gallopavo].	24.38	484	297	18	188	634	241	692	7e-13	82.8
rs:XP_010196093	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha [Colius striatus].	24.48	482	299	18	188	634	237	688	7e-13	82.8
rs:WP_028336381	DNA topoisomerase I [Bradyrhizobium elkanii].	23.11	688	415	28	1	630	1	632	7e-13	82.8
rs:XP_008631835	PREDICTED: DNA topoisomerase 3-alpha, partial [Corvus brachyrhynchos].	25.06	407	260	14	188	579	222	598	7e-13	82.8
tr:W0W4P1_ZYGBA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.89	664	390	26	3	584	4	627	7e-13	82.4
rs:WP_027284170	DNA topoisomerase I [Rubritepida flocculans].	23.03	482	315	15	85	534	61	518	7e-13	82.4
rs:XP_005426049	PREDICTED: DNA topoisomerase 3-alpha [Geospiza fortis].	24.69	482	298	18	188	634	239	690	7e-13	82.8
rs:XP_004291220	PREDICTED: uncharacterized protein LOC101314719 isoform X1 [Fragaria vesca subsp. vesca].	23.05	603	399	24	64	618	469	1054	7e-13	82.8
rs:WP_010733593	MULTISPECIES: hypothetical protein [Enterococcus].	39.29	112	64	3	3	111	4	114	7e-13	77.0
rs:WP_006344557	DNA topoisomerase I [Chlamydophila abortus].	23.98	588	325	23	3	534	5	526	7e-13	82.4
rs:WP_039728455	MULTISPECIES: DNA topoisomerase I [Oscillatoriophycideae].	23.83	575	341	17	3	530	4	528	7e-13	82.4
tr:A0A061B4A7_CYBFA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.83	623	382	21	3	565	4	581	7e-13	82.0
tr:A0A072VD72_MEDTR	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	26.52	362	220	13	64	391	301	650	7e-13	82.8
rs:XP_011006669	PREDICTED: uncharacterized protein LOC105112620 [Populus euphratica].	22.88	638	395	27	32	610	338	937	7e-13	82.8
rs:WP_006626394	DNA topoisomerase I [Bulleidia extructa].	23.57	666	406	27	3	630	4	604	7e-13	82.4
rs:WP_010731591	hypothetical protein [Enterococcus faecalis].	37.93	116	60	3	3	111	5	115	7e-13	77.0
rs:XP_009699312	PREDICTED: DNA topoisomerase 3-alpha [Cariama cristata].	24.43	483	298	18	188	634	241	692	7e-13	82.8
rs:WP_015114554	DNA topoisomerase I [Nostoc sp. PCC 7107].	24.33	600	370	22	79	631	59	621	7e-13	82.4
rs:WP_032496840	DNA topoisomerase I, partial [Hydrogenivirga sp. 128-5-R1-1].	22.35	595	387	16	2	576	4	543	7e-13	82.0
rs:XP_010669509	PREDICTED: uncharacterized protein LOC104886724 isoform X2 [Beta vulgaris subsp. vulgaris].	22.79	610	378	21	64	610	204	783	7e-13	82.4
rs:WP_035270855	DNA topoisomerase I, partial [Desulfonatronum thiodismutans].	22.22	657	409	26	76	679	53	660	7e-13	82.4
tr:A0A0D1PJJ0_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.95	697	427	25	3	632	1	647	7e-13	82.4
rs:WP_015335647	DNA topoisomerase 1 [Desulfovibrio hydrothermalis].	22.01	686	407	24	3	639	5	611	7e-13	82.4
rs:WP_045284154	DNA topoisomerase I [Enterobacter sp. 35032].	23.46	584	363	23	90	640	65	597	7e-13	82.0
tr:A0A0D2A416_9PEZI	SubName: Full=Verruconis gallopava strain CBS 43764 unplaced genomic scaffold supercont1.28, whole genome shotgun sequence {ECO:0000313|EMBL:KIW01215.1};	22.14	560	365	19	3	525	5	530	7e-13	82.0
tr:A0A061I877_CRIGR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.64	414	262	14	188	585	143	522	7e-13	82.4
rs:WP_005044934	DNA topoisomerase I [Acinetobacter calcoaceticus].	23.14	579	358	18	90	629	116	646	7e-13	82.4
rs:WP_028872666	DNA topoisomerase I [Psychroserpens burtonensis].	25.86	379	241	11	154	521	128	477	7e-13	82.4
tr:G8PNI3_PSEUV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.09	523	322	16	55	534	22	512	7e-13	82.4
rs:WP_010991808	TraB protein [uncultured bacterium].	23.48	575	362	22	90	631	74	603	7e-13	82.4
rs:WP_026827998	DNA topoisomerase I [Exiguobacterium sibiricum].	22.89	664	415	25	3	630	5	607	7e-13	82.4
rs:WP_039418184	DNA topoisomerase I [Porphyromonas gulae].	23.87	532	334	16	3	520	4	478	8e-13	82.4
tr:K2MRY5_TRYCR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.11	588	352	23	46	582	55	587	8e-13	82.4
rs:WP_036884967	DNA topoisomerase I, partial [Prevotella disiens].	31.82	176	102	5	4	168	5	173	8e-13	78.2
rs:WP_014544362	topoisomerase I [Erwinia sp. Ejp617].	21.54	520	339	15	187	673	190	673	8e-13	82.4
tr:A0A091KTW7_9GRUI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.22	483	299	18	188	634	221	672	8e-13	82.4
rs:WP_010623475	DNA topoisomerase I [Lactobacillus versmoldensis].	23.03	673	414	24	3	635	7	615	8e-13	82.0
rs:WP_036857344	hypothetical protein, partial [Prevotella amnii].	29.86	211	135	8	466	673	7	207	8e-13	79.0
tr:A0A072VE62_MEDTR	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	26.52	362	220	13	64	391	301	650	8e-13	82.4
rs:WP_024495662	DNA topoisomerase I [Candidatus Schmidhempelia bombi].	23.20	612	387	24	63	633	67	636	8e-13	82.4
rs:WP_040234733	DNA topoisomerase I, partial [Klebsiella pneumoniae].	22.95	488	320	13	60	533	78	523	8e-13	82.0
rs:WP_039445801	DNA topoisomerase I [Porphyromonas gulae].	23.87	532	334	16	3	520	4	478	8e-13	82.4
tr:A0A083VKF9_BRUSS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.61	690	415	29	1	629	10	641	8e-13	82.4
rs:WP_029701702	DNA topoisomerase I [Clostridium sp. ASBs410].	23.71	561	358	19	90	616	67	591	8e-13	82.0
rs:WP_006915959	DNA topoisomerase I [Lactobacillus coleohominis].	22.80	579	371	22	88	629	84	623	8e-13	82.0
rs:WP_029523172	DNA topoisomerase I [Persephonella sp. KM09-Lau-8].	24.05	524	346	15	90	593	69	560	8e-13	82.0
rs:WP_040146912	DNA topoisomerase III, partial [Xanthomonas citri].	30.39	181	113	5	465	639	11	184	8e-13	78.6
rs:WP_006996844	DNA topoisomerase I [Candidatus Pelagibacter ubique].	22.70	696	402	31	1	629	1	627	8e-13	82.4
rs:WP_029435682	DNA topoisomerase I [Bilophila wadsworthia].	23.25	572	365	20	76	614	53	583	8e-13	82.4
rs:WP_031295641	DNA topoisomerase I [Leuconostoc mesenteroides].	22.32	560	361	18	90	616	89	607	8e-13	82.0
rs:WP_007854957	DNA topoisomerase I [Bacteroides dorei].	24.73	562	352	19	77	617	54	565	8e-13	82.4
rs:WP_007841944	DNA topoisomerase I [Bacteroides dorei].	24.73	562	352	19	77	617	54	565	8e-13	82.4
rs:WP_039425546	DNA topoisomerase I [Porphyromonas gulae].	23.87	532	334	16	3	520	4	478	8e-13	82.4
rs:XP_010138219	PREDICTED: DNA topoisomerase 3-alpha, partial [Buceros rhinoceros silvestris].	24.79	484	295	19	188	634	179	630	8e-13	82.4
tr:A0A093QKD6_9PASS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.94	409	258	14	188	577	179	557	8e-13	82.4
tr:A0A091EPK2_CORBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.06	407	260	14	188	579	221	597	8e-13	82.4
rs:WP_010521566	DNA topoisomerase I [Flavobacteriaceae bacterium HQM9].	25.91	440	283	14	93	521	70	477	8e-13	82.4
rs:WP_026721293	DNA topoisomerase I [Fischerella sp. PCC 9431].	22.93	615	366	19	3	560	4	567	8e-13	82.4
rs:WP_008189836	DNA topoisomerase I [Moorea producens].	24.34	608	359	21	3	560	4	560	8e-13	82.4
rs:WP_008510669	DNA topoisomerase I [Brucella inopinata].	22.61	690	415	29	1	629	1	632	8e-13	82.4
tr:T0CZ37_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.09	193	117	6	200	380	1	189	8e-13	78.2
rs:WP_034508708	DNA topoisomerase I [Agrobacterium rhizogenes].	21.90	662	408	26	38	630	16	637	8e-13	82.4
rs:WP_008674276	DNA topoisomerase I [Bacteroides sp. 9_1_42FAA].	24.73	562	352	19	77	617	54	565	8e-13	82.4
rs:WP_019191838	DNA topoisomerase I [Anaerococcus pacaensis].	24.10	668	395	26	3	630	5	600	8e-13	82.0
rs:WP_018271983	DNA topoisomerase I [Bradyrhizobium elkanii].	22.97	688	416	28	1	630	1	632	8e-13	82.4
rs:WP_002321672	topoisomerase [Enterococcus faecium].	39.29	112	64	3	3	111	4	114	8e-13	76.6
rs:WP_046431670	DNA topoisomerase I [Ruminococcus sp. A254.MGS-108].	23.90	590	349	19	76	616	52	590	8e-13	82.0
rs:WP_007847280	DNA topoisomerase I [Bacteroides dorei].	24.73	562	352	19	77	617	54	565	8e-13	82.4
rs:WP_044225531	DNA topoisomerase I [Flammeovirga pacifica].	25.33	537	322	19	3	520	5	481	8e-13	82.4
rs:XP_010120298	PREDICTED: DNA topoisomerase 3-alpha [Chlamydotis macqueenii].	24.22	483	299	18	188	634	241	692	8e-13	82.4
rs:WP_021720800	DNA topoisomerase [Phascolarctobacterium succinatutens].	25.14	545	316	23	88	589	68	563	8e-13	82.0
rs:WP_012177809	DNA topoisomerase I [Dinoroseobacter shibae].	22.19	604	343	21	1	534	1	547	8e-13	82.4
rs:WP_029558610	DNA topoisomerase I [Xanthobacter sp. 91].	22.53	697	409	29	1	630	1	633	8e-13	82.4
rs:WP_015199931	DNA topoisomerase I [Calothrix parietina].	24.13	572	341	23	88	610	74	601	8e-13	82.0
rs:WP_012460317	reverse gyrase [Sulfurihydrogenibium sp. YO3AOP1].	24.10	556	331	20	3	533	599	1088	8e-13	82.4
rs:WP_003628391	DNA topoisomerase I [Acetobacter pasteurianus].	22.80	636	400	25	55	629	28	633	8e-13	82.4
tr:A0A0E0A851_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OGLUM06G11680.2};	23.83	575	353	25	64	583	339	883	8e-13	82.4
rs:WP_009644989	DNA topoisomerase I [Selenomonas sp. CM52].	22.62	557	364	18	90	616	175	694	9e-13	82.4
tr:A0A0D6NAU5_9PROT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAN62760.1};	22.31	641	399	23	55	630	28	634	9e-13	82.4
tr:W1E0K2_KLEPN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.95	488	320	13	60	533	78	523	9e-13	82.0
rs:WP_016419510	DNA topoisomerase I [Capnocytophaga granulosa].	25.24	531	327	18	3	521	5	477	9e-13	82.4
rs:WP_028341022	DNA topoisomerase I [Bradyrhizobium elkanii].	23.11	688	415	28	1	630	1	632	9e-13	82.4
rs:WP_032104631	DNA topoisomerase I, partial [Klebsiella pneumoniae].	22.95	488	320	13	60	533	78	523	9e-13	81.6
tr:A0A0D2X5L3_CAPO3	SubName: Full=Topoisomerase III {ECO:0000313|EMBL:KJE98009.1};	22.24	634	363	27	3	560	203	782	9e-13	82.4
rs:WP_014746067	DNA topoisomerase I [Tistrella mobilis].	22.98	570	336	22	1	528	1	509	9e-13	82.4
rs:WP_014850163	DNA topoisomerase I [Mycoplasma wenyonii].	23.82	638	396	20	90	678	73	669	9e-13	82.0
rs:WP_016504046	DNA topoisomerase [Candidatus Photodesmus katoptron].	24.03	591	376	21	77	633	90	641	9e-13	82.4
rs:WP_034919220	DNA topoisomerase I [Gillisia sp. CAL575].	26.84	462	289	18	74	521	51	477	9e-13	82.4
rs:WP_008655482	MULTISPECIES: DNA topoisomerase I [Bacteroides].	24.73	562	352	19	77	617	54	565	9e-13	82.0
rs:WP_024653225	DNA topoisomerase I [Borrelia persica].	24.23	648	361	29	2	587	5	584	9e-13	82.0
rs:WP_004332751	DNA topoisomerase III [Porphyromonas endodontalis].	36.64	131	68	4	1	121	1	126	9e-13	77.0
rs:WP_017726920	hypothetical protein, partial [Bacillus sp. L1(2012)].	29.17	192	120	5	486	661	2	193	9e-13	78.6
tr:I1P7W6_ORYGL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.49	740	444	32	3	653	13	704	9e-13	82.4
rs:WP_029509338	DNA topoisomerase I [Leuconostoc lactis].	22.26	539	361	15	103	616	108	613	9e-13	82.0
rs:WP_011153042	hypothetical protein [Nanoarchaeum equitans].	27.34	406	248	15	3	393	2	375	9e-13	80.9
tr:A0A068WM85_ECHGR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.48	647	412	20	35	620	47	658	9e-13	82.4
rs:WP_026966063	DNA topoisomerase I [Algoriphagus terrigena].	26.32	399	243	11	3	392	5	361	9e-13	82.0
rs:WP_038388563	DNA topoisomerase I [Bradyrhizobium elkanii].	22.17	690	419	25	1	630	1	632	9e-13	82.4
rs:WP_009625014	DNA topoisomerase I [Pseudanabaena biceps].	21.80	500	312	14	157	610	136	602	9e-13	82.0
rs:WP_042811193	DNA topoisomerase III, partial [Xanthomonas citri].	30.39	181	113	5	465	639	31	204	9e-13	78.6
tr:U1DS88_ENTGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	24.26	404	249	16	249	629	14	383	9e-13	80.9
rs:WP_015506487	DNA topoisomerase I/SWI domain fusion protein [Chlamydia trachomatis].	22.56	656	402	25	3	612	5	600	9e-13	82.0
rs:WP_029551795	reverse gyrase [Thermocrinis sp. GBS].	23.35	621	379	22	3	598	596	1144	9e-13	82.4
rs:WP_015418886	MULTISPECIES: reverse gyrase [Hydrogenobaculum].	23.77	631	339	25	3	560	585	1146	9e-13	82.4
rs:WP_003712564	hypothetical protein, partial [Lactobacillus oris].	29.45	146	101	1	438	581	1	146	9e-13	79.0
rs:WP_031445426	DNA topoisomerase I [Arenibacter algicola].	24.95	529	333	16	3	521	5	479	9e-13	82.0
rs:WP_043553820	DNA topoisomerase I, partial [Acetobacter malorum].	21.36	618	386	18	55	631	28	586	9e-13	81.6
rs:WP_026356103	DNA topoisomerase I [Pannonibacter phragmitetus].	24.96	577	336	26	1	534	1	523	9e-13	82.0
rs:WP_012370758	DNA topoisomerase I [Exiguobacterium sibiricum].	22.74	664	416	25	3	630	5	607	9e-13	82.0
rs:WP_000308597	DNA topoisomerase I subunit omega, partial [Acinetobacter baumannii].	23.63	474	284	15	192	629	1	432	1e-12	82.0
tr:S7ZP59_PENO1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.96	636	379	24	3	573	6	595	1e-12	81.6
rs:WP_000317025	DNA topoisomerase I subunit omega, partial [Escherichia coli].	22.97	444	282	16	256	673	26	435	1e-12	81.6
tr:T0ZGE6_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD27944.1}; Flags: Fragment;	30.86	162	104	3	424	581	14	171	1e-12	77.8
rs:WP_002333457	hypothetical protein [Enterococcus faecium].	37.07	116	61	3	3	111	4	114	1e-12	76.6
rs:WP_016179974	DNA topoisomerase 1 [Enterococcus avium].	24.06	586	366	24	90	635	68	614	1e-12	82.0
rs:XP_009487964	PREDICTED: DNA topoisomerase 3-alpha [Pelecanus crispus].	24.22	483	299	18	188	634	241	692	1e-12	82.4
rs:WP_034545244	DNA topoisomerase I [Clostridiales bacterium S7-1-4].	24.78	557	315	18	163	671	139	639	1e-12	82.0
rs:WP_036090489	DNA topoisomerase I [Leuconostoc mesenteroides].	22.14	560	362	18	90	616	87	605	1e-12	82.0
rs:WP_002715487	DNA topoisomerase I [Afipia felis].	23.22	689	414	31	1	630	1	633	1e-12	82.0
tr:A0A091MVC1_CARIC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.43	483	298	18	188	634	221	672	1e-12	82.4
tr:A0A091U1D3_9AVES	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.22	483	299	18	188	634	221	672	1e-12	82.0
rs:WP_014812474	DNA topoisomerase I [Desulfomonile tiedjei].	22.56	585	368	16	76	616	53	596	1e-12	82.0
tr:A8V019_9AQUI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.06	607	368	18	2	576	4	543	1e-12	81.6
rs:XP_009647736	PREDICTED: DNA topoisomerase 3-alpha [Egretta garzetta].	24.22	483	299	18	188	634	241	692	1e-12	82.0
rs:WP_034558155	topoisomerase [Carnobacterium gallinarum].	37.07	116	61	3	3	111	4	114	1e-12	76.6
rs:WP_016532151	DNA topoisomerase I subunit omega, partial [Klebsiella pneumoniae].	22.95	488	320	13	60	533	78	523	1e-12	81.3
rs:WP_022292352	DNA topoisomerase [Staphylococcus sp. CAG:324].	24.08	706	430	29	1	668	1	638	1e-12	82.0
rs:XP_008659453	PREDICTED: uncharacterized protein LOC103638270 isoform X1 [Zea mays].	23.26	516	321	19	64	536	353	836	1e-12	82.4
rs:WP_013459042	DNA topoisomerase I [Sulfuricurvum kujiense].	23.58	581	314	21	1	533	1	499	1e-12	82.0
rs:XP_010745514	PREDICTED: DNA topoisomerase 3-alpha [Larimichthys crocea].	22.54	488	303	16	188	634	244	697	1e-12	82.0
rs:XP_010669508	PREDICTED: uncharacterized protein LOC104886724 isoform X1 [Beta vulgaris subsp. vulgaris].	22.79	610	378	21	64	610	436	1015	1e-12	82.4
rs:WP_029665944	hypothetical protein [Calescamantes bacterium JGI 0000106-N5].	25.59	512	297	16	81	552	755	1222	1e-12	82.4
rs:WP_029343511	DNA topoisomerase I [Lactococcus garvieae].	24.37	558	354	22	103	630	109	628	1e-12	82.0
rs:WP_018953624	DNA topoisomerase I [Thioalkalivibrio sp. ALJ17].	23.51	570	344	21	3	534	5	520	1e-12	82.0
rs:WP_042037111	DNA topoisomerase III, partial [Escherichia coli].	30.05	213	129	8	1	202	1	204	1e-12	78.2
rs:WP_010001831	DNA topoisomerase I [Leuconostoc lactis].	22.08	539	362	15	103	616	108	613	1e-12	81.6
rs:WP_021326602	DNA topoisomerase III, partial [Photorhabdus temperata].	26.59	173	119	2	449	614	27	198	1e-12	79.0
rs:WP_003678435	DNA topoisomerase I [Lactobacillus coryniformis].	23.17	574	371	19	90	629	68	605	1e-12	81.6
rs:WP_018628260	DNA topoisomerase I [Niabella aurantiaca].	24.24	594	373	16	3	580	5	537	1e-12	82.0
rs:WP_008510351	DNA topoisomerase I [Mucilaginibacter paludis].	23.08	572	361	17	31	580	18	532	1e-12	82.0
tr:M0WQP2_HORVD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.07	639	394	23	3	585	11	601	1e-12	81.6
rs:WP_032534215	DNA topoisomerase I [Bacteroides fragilis].	24.60	626	370	29	3	604	5	552	1e-12	82.0
rs:XP_009284732	PREDICTED: DNA topoisomerase 3-alpha [Aptenodytes forsteri].	24.48	478	298	17	188	631	241	689	1e-12	82.0
rs:WP_036884644	DNA topoisomerase I, partial [Prevotella disiens].	31.25	176	103	5	4	168	5	173	1e-12	77.8
rs:WP_005791192	MULTISPECIES: DNA topoisomerase I [Bacteroides].	24.60	626	370	29	3	604	5	552	1e-12	82.0
rs:WP_024823998	DNA topoisomerase I [Desulfovibrio magneticus].	23.20	651	389	25	76	669	53	649	1e-12	82.0
rs:WP_029485745	topoisomerase, partial [Enterococcus faecium].	37.29	118	62	3	3	113	4	116	1e-12	76.6
rs:WP_020966639	DNA topoisomerase I [Chlamydia trachomatis].	22.14	655	406	24	3	612	5	600	1e-12	82.0
tr:A0A0C2LHI1_STAAU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KII19923.1};	35.14	148	90	2	82	223	4	151	1e-12	77.8
rs:WP_038380389	DNA topoisomerase I [Bradyrhizobium elkanii].	22.97	688	416	28	1	630	1	632	1e-12	82.0
tr:G1FGU3_9CHLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.95	497	306	18	82	536	59	530	1e-12	82.0
rs:XP_008926440	PREDICTED: DNA topoisomerase 3-alpha [Manacus vitellinus].	24.63	406	259	15	188	577	219	593	1e-12	82.0
rs:WP_029563674	DNA topoisomerase I [alpha proteobacterium SCGC AAA240-E13].	23.47	754	418	39	1	676	1	673	1e-12	82.0
rs:WP_046369750	DNA topoisomerase I [Flavihumibacter petaseus].	23.36	625	391	24	3	604	5	564	1e-12	82.0
rs:WP_004363587	DNA topoisomerase I [Prevotella nigrescens].	21.87	599	384	17	3	580	5	540	1e-12	82.0
rs:WP_032569135	DNA topoisomerase I [Bacteroides fragilis].	24.60	626	370	29	3	604	5	552	1e-12	82.0
tr:D4L803_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.90	590	349	19	76	616	52	590	1e-12	81.6
rs:WP_045796399	DNA topoisomerase I [Acinetobacter indicus].	23.55	484	282	17	187	629	210	646	1e-12	82.0
rs:WP_005182090	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	23.55	484	282	17	187	629	210	646	1e-12	82.0
rs:WP_010825641	hypothetical protein, partial [Enterococcus faecalis].	39.47	114	65	3	3	113	4	116	1e-12	76.3
rs:WP_021665548	DNA topoisomerase I [Porphyromonas gingivalis].	23.68	532	335	16	3	520	4	478	1e-12	82.0
tr:E9H1M6_DAPPU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.82	677	377	36	24	634	53	663	1e-12	82.0
tr:A0A0D1XG93_9PEZI	SubName: Full=Verruconis gallopava strain CBS 43764 unplaced genomic scaffold supercont1.28, whole genome shotgun sequence {ECO:0000313|EMBL:KIW01216.1};	22.14	560	365	19	3	525	5	530	1e-12	81.6
rs:WP_004028404	DNA topoisomerase I [Spiroplasma melliferum].	25.34	517	321	17	38	533	24	496	1e-12	81.6
rs:WP_013269241	DNA topoisomerase I [Brevundimonas subvibrioides].	21.24	692	422	23	1	630	1	631	1e-12	82.0
rs:WP_029169592	hypothetical protein [Clostridium botulinum].	35.66	129	76	3	3	128	5	129	1e-12	77.0
tr:S4RC13_PETMA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.93	484	303	17	188	634	239	689	1e-12	82.0
rs:WP_014974405	DNA topoisomerase I [Leuconostoc carnosum].	22.12	669	408	26	3	629	30	627	1e-12	81.6
rs:WP_004448953	DNA topoisomerase I [Acetobacter pasteurianus].	22.80	636	400	25	55	629	28	633	1e-12	82.0
rs:WP_032590962	DNA topoisomerase I [Bacteroides fragilis].	24.60	626	370	29	3	604	5	552	1e-12	81.6
rs:WP_025133176	DNA topoisomerase I [Leucobacter sp. PH1c].	22.93	641	376	24	2	574	6	596	1e-12	82.0
rs:WP_021901316	DNA topoisomerase [Coprobacillus sp. CAG:698].	21.12	663	423	22	2	630	4	600	1e-12	81.6
rs:WP_006116241	DNA topoisomerase I [Acetobacter pomorum].	22.96	636	399	26	55	629	28	633	1e-12	82.0
tr:A5ZUI2_9FIRM	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:EDM86762.1};	25.38	260	167	8	346	579	19	277	1e-12	79.3
rs:WP_033874305	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	31.76	148	96	3	271	413	1	148	1e-12	77.8
rs:WP_012562937	DNA topoisomerase I [Oligotropha carboxidovorans].	22.58	691	416	31	1	630	1	633	1e-12	82.0
rs:XP_006875592	PREDICTED: DNA topoisomerase 3-alpha [Chrysochloris asiatica].	23.21	517	329	19	188	667	214	699	1e-12	82.0
rs:WP_045874334	DNA topoisomerase I [Tolypothrix sp. PCC 7601].	23.37	582	357	19	79	610	59	601	1e-12	81.6
rs:WP_020169475	DNA topoisomerase I [Candidatus Pelagibacter ubique].	22.56	696	403	31	1	629	1	627	1e-12	82.0
rs:WP_000108744	MULTISPECIES: topoisomerase [Bacilli].	37.07	116	61	3	3	111	4	114	1e-12	76.3
rs:WP_006589617	DNA topoisomerase I [Bartonella birtlesii].	23.41	692	408	28	1	629	1	633	1e-12	81.6
rs:WP_036280765	DNA topoisomerase I [Methylocystis sp. ATCC 49242].	22.81	640	396	25	55	630	27	632	1e-12	82.0
rs:WP_008204102	DNA topoisomerase I [Roseobacter sp. SK209-2-6].	23.43	589	335	23	1	534	1	528	1e-12	82.0
rs:WP_029666628	hypothetical protein [Calescamantes bacterium JGI 0000106-M22].	25.59	512	297	16	81	552	755	1222	1e-12	82.0
rs:WP_044820000	DNA topoisomerase I [Bacteroides fragilis].	25.63	554	337	25	74	604	35	536	1e-12	81.6
rs:WP_012636779	DNA topoisomerase I [Thioalkalivibrio sulfidiphilus].	23.37	522	328	19	55	534	29	520	1e-12	81.6
rs:WP_012626533	DNA topoisomerase I [Cyanothece sp. PCC 7425].	22.73	572	349	15	90	614	71	596	1e-12	81.6
rs:WP_022789185	DNA topoisomerase I [[Streptococcus] pleomorphus].	24.18	550	326	20	3	524	5	491	1e-12	81.6
rs:WP_011006940	DNA topoisomerase I [Chlamydophila caviae].	24.26	577	337	22	3	534	5	526	1e-12	81.6
rs:WP_043455798	DNA topoisomerase I, partial [Granulibacter bethesdensis].	21.45	634	413	23	55	630	28	634	1e-12	81.6
rs:XP_005706718	DNA topoisomerase III alpha [Galdieria sulphuraria].	21.79	670	435	27	3	620	5	637	1e-12	81.6
rs:WP_026063875	DNA topoisomerase I [Lactococcus garvieae].	24.19	558	355	22	103	630	109	628	1e-12	81.6
rs:WP_000655385	DNA topoisomerase I [Helicobacter pylori].	24.93	373	257	10	75	425	46	417	1e-12	81.6
rs:XP_008659455	PREDICTED: uncharacterized protein LOC103638270 isoform X3 [Zea mays].	23.64	516	319	19	64	536	353	836	1e-12	82.0
rs:WP_046400358	DNA topoisomerase III, partial [Staphylococcus aureus].	36.42	151	73	4	475	615	1	138	1e-12	78.6
rs:WP_029955435	DNA topoisomerase I [Atribacteria bacterium SCGC AAA255-N14].	23.59	602	381	19	85	644	59	623	1e-12	81.6
tr:A0A093FX84_PICPB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.71	485	299	18	188	634	221	672	1e-12	82.0
rs:XP_012081967	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Jatropha curcas].	22.52	635	399	25	3	585	5	598	1e-12	81.6
rs:XP_002379355	DNA topoisomerase III, putative [Aspergillus flavus NRRL3357].	22.60	646	385	24	3	581	7	604	1e-12	81.3
rs:WP_002659914	DNA topoisomerase I [Saprospira grandis].	23.38	432	294	10	74	481	54	472	1e-12	81.6
rs:XP_012171190	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Bombus terrestris].	22.38	648	396	25	46	634	58	657	1e-12	82.0
tr:K5BPD2_LEPME	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EKJ85502.1};	23.61	466	293	10	162	596	33	466	1e-12	81.3
rs:WP_046784256	DNA topoisomerase I [Mycoplasma capricolum].	23.17	669	401	29	3	625	4	605	1e-12	81.3
rs:WP_019388230	DNA topoisomerase I [Arenitalea lutea].	23.21	655	407	23	3	621	5	599	1e-12	81.6
rs:WP_013751171	DNA topoisomerase I [Dokdonia sp. 4H-3-7-5].	25.42	535	321	19	3	521	5	477	1e-12	81.6
rs:WP_021843600	DNA topoisomerase [Bacteroides sp. CAG:1060].	25.92	436	242	15	3	406	5	391	1e-12	81.6
tr:M5G9P4_DACSP	SubName: Full=Prokaryotic type I DNA topoisomerase {ECO:0000313|EMBL:EJU05529.1};	23.75	640	381	29	3	585	4	593	1e-12	81.6
rs:WP_025018184	DNA topoisomerase I [Bacteroides sartorii].	24.78	561	353	19	77	617	54	565	1e-12	81.6
rs:WP_044343070	DNA topoisomerase I [Pseudomonas oryzihabitans].	22.35	595	361	21	90	641	65	601	1e-12	81.3
tr:A6NXR7_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EDM99087.1};	36.64	131	82	1	497	627	14	143	1e-12	78.2
tr:G3XZ45_ASPNA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.64	636	381	24	3	573	7	596	1e-12	81.3
tr:A0A087RG32_APTFO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.69	478	297	18	188	631	221	669	1e-12	81.6
tr:W6TY68_9SPHI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.04	338	228	8	77	406	54	377	1e-12	80.5
tr:A0A087PJ20_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.36	618	386	18	55	631	28	586	1e-12	81.3
rs:WP_002295589	MULTISPECIES: topoisomerase [Enterococcus].	37.07	116	61	3	3	111	4	114	1e-12	76.3
rs:WP_046001383	DNA topoisomerase I [Paracoccus sp. 361].	21.28	705	433	25	1	630	1	658	1e-12	81.6
rs:WP_004066811	DNA topoisomerase I [Thermococcus litoralis].	25.90	332	169	10	359	639	55	360	1e-12	80.1
rs:WP_038960642	DNA topoisomerase I [Atribacteria bacterium SCGC AB-164-A22].	24.53	579	355	20	103	639	80	618	1e-12	81.6
rs:WP_033641536	DNA topoisomerase, partial [Enterococcus faecium].	36.20	163	92	5	92	244	1	161	1e-12	77.4
rs:WP_032584877	DNA topoisomerase I [Bacteroides fragilis].	24.32	625	373	27	3	604	5	552	1e-12	81.6
rs:WP_022012244	DNA topoisomerase [Bacteroides fragilis CAG:558].	23.89	628	372	27	3	604	5	552	1e-12	81.6
rs:XP_007362084	prokaryotic type I DNA topoisomerase, partial [Dichomitus squalens LYAD-421 SS1].	23.09	628	400	23	3	584	4	594	1e-12	81.6
rs:WP_015810713	DNA topoisomerase I [Dyadobacter fermentans].	24.62	459	297	13	77	520	54	478	1e-12	81.6
tr:W5Q119_SHEEP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.50	520	345	18	3	481	5	507	1e-12	81.3
tr:D4K6P1_9FIRM	SubName: Full=Draft genome {ECO:0000313|EMBL:CBL00504.1};	35.09	114	58	4	1	107	1	105	1e-12	75.9
rs:WP_019089708	DNA topoisomerase I [Acetobacter pasteurianus].	22.87	634	402	25	55	629	28	633	1e-12	81.6
rs:WP_002708740	DNA topoisomerase I [Thiothrix nivea].	24.28	519	326	18	55	534	29	519	1e-12	81.6
rs:WP_037975704	DNA topoisomerase I [Synergistes jonesii].	22.80	671	401	26	3	629	85	682	1e-12	81.6
rs:WP_023462771	DNA topoisomerase I [Asticcacaulis sp. YBE204].	20.14	720	457	21	1	659	1	663	1e-12	81.6
rs:WP_015157793	DNA topoisomerase I [Chamaesiphon minutus].	24.25	631	361	27	3	574	4	576	1e-12	81.6
rs:WP_000655386	DNA topoisomerase I [Helicobacter pylori].	24.93	373	257	10	75	425	46	417	1e-12	81.3
rs:WP_008261370	DNA topoisomerase I [Brevundimonas sp. BAL3].	22.30	556	342	20	1	520	1	502	1e-12	81.6
rs:WP_004826641	DNA topoisomerase I [Acinetobacter bereziniae].	23.68	587	377	18	74	629	102	648	1e-12	81.6
tr:B7BDS5_9PORP	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EEC95424.1};	35.94	128	65	4	1	117	1	122	1e-12	77.0
rs:WP_037272240	DNA topoisomerase I [Roseovarius mucosus].	26.59	331	192	10	1	312	1	299	1e-12	81.6
tr:G3NY56_GASAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.59	496	288	19	188	634	206	659	1e-12	81.3
rs:WP_038547907	DNA topoisomerase I [Synechococcus sp. KORDI-100].	22.72	625	373	23	3	572	5	574	1e-12	81.6
rs:WP_013816449	DNA topoisomerase I [Porphyromonas gingivalis].	23.68	532	335	16	3	520	4	478	1e-12	81.6
rs:WP_044102077	DNA topoisomerase III, partial [Xanthomonas citri].	29.12	182	115	3	437	611	33	207	1e-12	77.8
rs:WP_034233047	DNA topoisomerase I [Arcanobacterium sp. S3PF19].	23.45	631	373	24	2	572	3	583	1e-12	81.6
rs:XP_012749000	hypothetical protein SAMD00019534_112170 [Acytostelium subglobosum LB1].	22.25	773	443	36	1	669	1	719	1e-12	81.3
rs:WP_025307436	DNA topoisomerase I [Bdellovibrio bacteriovorus].	23.59	585	335	23	1	530	10	537	1e-12	81.6
rs:WP_016533828	DNA topoisomerase I subunit omega, partial [Pasteurella multocida].	24.73	372	225	11	283	631	2	341	1e-12	80.9
tr:A4AKC9_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.81	588	329	20	2	528	6	535	1e-12	81.6
tr:A0A077LXP7_9MICO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.52	506	305	16	77	530	70	545	1e-12	81.6
rs:WP_002355646	hypothetical protein, partial [Enterococcus faecium].	29.80	198	123	6	485	667	3	199	1e-12	78.2
tr:K2EC32_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.49	557	312	20	1	521	1	490	1e-12	81.3
rs:WP_010518278	DNA topoisomerase I [Mesoflavibacter zeaxanthinifaciens].	23.82	617	390	18	3	602	5	558	1e-12	81.6
rs:WP_033916179	DNA topoisomerase I [Campylobacter sputorum].	23.64	643	393	24	3	614	4	579	1e-12	81.3
rs:WP_013358013	MULTISPECIES: topoisomerase I [Pantoea].	23.05	603	373	24	75	633	88	643	1e-12	81.6
rs:XP_009894971	PREDICTED: DNA topoisomerase 3-alpha [Picoides pubescens].	23.71	485	299	18	188	634	241	692	1e-12	81.6
rs:WP_013133690	DNA topoisomerase I [Thermobispora bispora].	23.60	589	337	23	2	530	12	547	1e-12	81.6
rs:WP_045866076	DNA topoisomerase I [Streptomyces sp. WMMB 714].	23.66	596	327	24	2	530	13	547	1e-12	81.6
rs:XP_005523120	PREDICTED: DNA topoisomerase 3-alpha [Pseudopodoces humilis].	24.87	394	246	13	188	564	227	587	2e-12	81.6
tr:A0A067JZR5_JATCU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.05	644	395	25	3	589	5	598	2e-12	81.3
rs:WP_009144603	DNA topoisomerase I [Phascolarctobacterium succinatutens].	25.70	537	323	21	88	589	68	563	2e-12	81.3
rs:WP_046756567	DNA topoisomerase I [Kordia jejudonensis].	24.40	668	383	26	3	621	5	599	2e-12	81.3
tr:A5DM60_PICGU	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EDK40263.2};	22.41	607	386	20	3	560	4	574	2e-12	81.3
rs:WP_019585340	DNA topoisomerase I [Deinococcus apachensis].	23.43	589	334	21	3	530	5	537	2e-12	81.6
rs:XP_012081965	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Jatropha curcas].	22.52	635	399	25	3	585	5	598	2e-12	81.6
rs:WP_045529134	DNA topoisomerase I [Clavibacter michiganensis].	23.00	587	338	20	2	528	6	538	2e-12	81.6
rs:WP_015489632	DNA topoisomerase I A [Clavibacter michiganensis].	23.17	587	337	21	2	528	6	538	2e-12	81.6
gp:KJ850907_18	TraB [uncultured bacterium]	23.48	575	362	22	90	631	74	603	2e-12	81.3
rs:WP_019281329	hypothetical protein [Vibrio anguillarum].	22.36	644	390	23	58	644	22	612	2e-12	81.3
rs:WP_032821507	topoisomerase I, partial [Oenococcus oeni].	27.89	147	104	1	437	581	1	147	2e-12	77.8
rs:WP_011097448	DNA topoisomerase I [Chlamydophila abortus].	23.98	588	325	23	3	534	5	526	2e-12	81.6
tr:T0RST2_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.68	608	366	23	2	566	71	623	2e-12	81.3
tr:A0A090M2L9_OSTTA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.82	605	382	24	3	557	6	569	2e-12	81.3
rs:WP_035308752	DNA topoisomerase I [Brevundimonas sp. EAKA].	22.30	556	342	20	1	520	1	502	2e-12	81.3
rs:WP_034722352	hypothetical protein, partial [Bacteriovorax sp. DB6_IX].	23.68	608	366	23	2	566	74	626	2e-12	81.3
rs:WP_012844201	DNA topoisomerase I [Rhodothermus marinus].	23.83	575	352	19	2	530	3	537	2e-12	81.3
rs:XP_003887131	topoisomerase IA [Encephalitozoon hellem ATCC 50504].	21.96	592	406	16	3	573	4	560	2e-12	81.3
tr:A0A034TZ32_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAJ77704.1};	37.14	140	81	3	89	221	1	140	2e-12	77.0
rs:WP_040800812	DNA topoisomerase I [marine actinobacterium PHSC20C1].	23.81	588	329	20	2	528	14	543	2e-12	81.6
rs:WP_043898447	DNA topoisomerase I [Porphyromonas gingivalis].	23.68	532	335	16	3	520	4	478	2e-12	81.3
rs:WP_005245924	DNA topoisomerase I [Acinetobacter sp. CIP 51.11].	24.06	478	287	16	187	629	212	648	2e-12	81.3
rs:WP_041660203	DNA topoisomerase I [Arcobacter nitrofigilis].	22.97	653	409	24	3	617	5	601	2e-12	81.3
rs:XP_012647749	uncharacterized protein [Babesia microti strain RI].	22.44	673	413	23	3	631	4	611	2e-12	81.3
rs:WP_024830849	DNA topoisomerase I [Methylobacterium sp. EUR3 AL-11].	22.30	686	421	27	1	629	1	631	2e-12	81.3
rs:WP_025370498	DNA topoisomerase I [Campylobacter fetus].	23.95	522	329	20	100	587	72	559	2e-12	80.9
rs:XP_002184774	predicted protein, partial [Phaeodactylum tricornutum CCAP 1055/1].	23.18	466	286	18	90	520	92	520	2e-12	80.9
rs:WP_021155407	MULTISPECIES: DNA topoisomerase I [Proteobacteria].	22.79	588	366	19	80	631	54	589	2e-12	81.3
rs:WP_012674047	reverse gyrase [Sulfurihydrogenibium azorense].	23.37	552	343	18	3	534	599	1090	2e-12	81.6
rs:WP_043387664	MULTISPECIES: DNA topoisomerase I [Methylobacterium].	22.74	686	418	27	1	629	1	631	2e-12	81.3
tr:G7XEX1_ASPKW	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.64	636	381	25	3	573	7	596	2e-12	80.9
tr:Q0BU00_GRABC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.45	634	413	23	55	630	39	645	2e-12	81.3
rs:XP_012171189	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Bombus terrestris].	22.38	648	396	25	46	634	91	690	2e-12	81.6
rs:WP_015153445	DNA topoisomerase I [Chroococcidiopsis thermalis].	22.09	611	374	17	3	560	4	565	2e-12	81.3
rs:XP_012171191	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Bombus terrestris].	22.38	648	396	25	46	634	8	607	2e-12	81.3
rs:WP_004647399	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	23.16	475	295	14	187	629	212	648	2e-12	81.3
rs:WP_043452743	DNA topoisomerase I [Granulibacter bethesdensis].	21.45	634	413	23	55	630	28	634	2e-12	81.3
rs:WP_005875040	DNA topoisomerase I [Porphyromonas gingivalis].	23.68	532	335	16	3	520	4	478	2e-12	81.3
rs:WP_016217314	hypothetical protein, partial [Dorea sp. 5-2].	36.73	98	48	3	1	93	1	89	2e-12	75.1
rs:WP_022251253	DNA topoisomerase [Prevotella sp. CAG:386].	22.54	630	385	20	3	602	16	572	2e-12	81.3
rs:WP_041159749	DNA topoisomerase I [Mycoplasma capricolum].	23.47	669	399	30	3	625	4	605	2e-12	80.9
rs:WP_021662118	DNA topoisomerase I [Porphyromonas gingivalis].	23.68	532	335	16	3	520	4	478	2e-12	81.3
rs:WP_034611665	DNA topoisomerase I [Acinetobacter sp. ETR1].	23.40	594	370	19	74	629	102	648	2e-12	81.3
rs:WP_024746280	DNA topoisomerase I [Lactobacillus namurensis].	23.91	598	355	25	88	635	78	625	2e-12	81.3
tr:R4I129_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.27	477	302	16	188	633	191	634	2e-12	81.3
rs:XP_001391772	DNA topoisomerase 3 [Aspergillus niger CBS 513.88].	22.64	636	381	24	3	573	7	596	2e-12	80.9
rs:WP_005107951	DNA topoisomerase I [Acinetobacter lwoffii].	23.16	475	295	14	187	629	212	648	2e-12	81.3
rs:WP_011441309	DNA topoisomerase I [Rhodopseudomonas palustris].	22.85	687	419	30	1	630	1	633	2e-12	81.3
rs:WP_005250631	DNA topoisomerase I [Acinetobacter sp. CIP 102136].	23.16	475	295	14	187	629	212	648	2e-12	81.3
rs:WP_021078311	DNA topoisomerase I [Bradyrhizobium sp. DFCI-1].	22.97	688	416	28	1	630	1	632	2e-12	81.3
rs:WP_004718025	DNA topoisomerase I [Acinetobacter guillouiae].	23.40	594	370	19	74	629	102	648	2e-12	81.3
rs:XP_011494373	PREDICTED: DNA topoisomerase 3-alpha [Ceratosolen solmsi marchali].	26.44	416	239	19	188	577	207	581	2e-12	81.3
rs:WP_025167044	DNA topoisomerase I [Pseudomonas taeanensis].	22.78	575	362	17	77	614	62	591	2e-12	80.9
rs:WP_004899308	DNA topoisomerase I [Acinetobacter brisouii].	22.01	477	298	13	187	629	212	648	2e-12	81.3
tr:Q5VMY4_ORYSJ	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	23.83	575	353	25	64	583	339	883	2e-12	81.3
rs:WP_006787029	DNA topoisomerase I [Thiorhodospira sibirica].	21.28	517	345	16	55	534	29	520	2e-12	81.3
rs:WP_015618537	DNA topoisomerase I [Actinoplanes sp. N902-109].	23.38	633	371	24	2	571	9	590	2e-12	81.3
rs:WP_039538908	DNA topoisomerase I [Ruegeria sp. ANG-R].	23.05	590	339	21	1	534	1	531	2e-12	81.3
rs:WP_020857205	DNA topoisomerase I [SAR86 cluster bacterium SAR86A].	23.10	593	368	21	75	629	87	629	2e-12	81.3
rs:WP_045801345	DNA topoisomerase I [Muricauda lutaonensis].	27.25	378	232	10	157	521	132	479	2e-12	81.3
tr:D2TAL0_ERWP6	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.35	520	340	15	187	673	165	648	2e-12	81.3
tr:W6QH12_PENRO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.95	622	364	23	3	560	6	582	2e-12	80.9
tr:A0A0C9XCQ7_9AGAR	SubName: Full=Unplaced genomic scaffold K443scaffold_54, whole genome shotgun sequence {ECO:0000313|EMBL:KIK02696.1};	22.04	626	390	21	3	577	4	582	2e-12	81.3
rs:XP_004342668	topoisomerase III [Capsaspora owczarzaki ATCC 30864].	22.24	634	363	27	3	560	203	782	2e-12	81.3
tr:A0A091NLP0_APAVI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.69	482	289	18	188	634	225	667	2e-12	81.3
gp:CP003183_2502	DNA topoisomerase I [Granulibacter bethesdensis CGDNIH2]	21.45	634	413	23	55	630	39	645	2e-12	81.3
rs:WP_032494176	topoisomerase I, partial [Enterococcus faecium].	37.07	116	61	3	3	111	4	114	2e-12	75.5
rs:WP_039439117	DNA topoisomerase I [Porphyromonas gulae].	23.68	532	335	16	3	520	4	478	2e-12	81.3
rs:WP_021809457	DNA topoisomerase I [Leifsonia rubra].	23.78	593	328	20	2	528	6	540	2e-12	81.3
rs:WP_025743036	DNA topoisomerase I [Aquimarina sp. SW150].	26.04	649	391	26	3	618	5	597	2e-12	81.3
rs:WP_036432487	DNA topoisomerase I [Mycoplasma capricolum].	23.17	669	401	29	3	625	4	605	2e-12	80.9
tr:T2N8B6_PORGN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.68	532	335	16	3	520	36	510	2e-12	81.3
rs:WP_004818820	DNA topoisomerase I [Acinetobacter guillouiae].	23.40	594	370	19	74	629	102	648	2e-12	81.3
rs:WP_033073131	DNA topoisomerase I [Sphingopyxis sp. MWB1].	21.50	665	436	22	1	629	1	615	2e-12	81.3
rs:WP_023930445	hypothetical protein [Helicobacter canis].	23.52	523	348	18	83	575	50	550	2e-12	80.9
tr:D5V7J0_ARCNC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.97	653	409	24	3	617	4	600	2e-12	81.3
rs:WP_024708367	DNA topoisomerase I [Martelella sp. AD-3].	22.70	718	385	33	1	630	1	636	2e-12	81.3
rs:WP_038487602	DNA topoisomerase I [Bartonella henselae].	22.92	698	404	29	1	629	1	633	2e-12	81.3
rs:WP_038276105	DNA topoisomerase I, partial [actinobacterium acAMD-5].	25.60	504	277	22	82	530	63	523	2e-12	81.3
rs:WP_035656189	DNA topoisomerase III, partial [Lachnospiraceae bacterium VE202-12].	33.14	175	109	4	505	673	3	175	2e-12	77.4
rs:WP_004813291	DNA topoisomerase I [Acinetobacter schindleri].	25.60	375	224	13	187	541	212	551	2e-12	81.3
tr:A0A0E0HP23_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA06G12620.2};	23.83	575	353	25	64	583	339	883	2e-12	81.3
rs:WP_024124916	DNA topoisomerase I TopA [Thermosynechococcus sp. NK55a].	22.35	613	390	17	3	572	4	573	2e-12	81.3
rs:WP_044197837	DNA topoisomerase I [Hyalangium minutum].	22.85	617	392	24	76	640	130	714	2e-12	81.3
rs:WP_002627127	DNA topoisomerase I [Cystobacter fuscus].	21.74	690	434	24	3	640	87	722	2e-12	81.3
rs:WP_042788503	DNA topoisomerase I [Acetobacter aceti].	22.64	636	401	26	55	629	28	633	2e-12	81.3
rs:WP_007310208	DNA topoisomerase I [Crocosphaera watsonii].	23.78	534	318	16	77	560	38	532	2e-12	81.3
rs:WP_031058622	DNA topoisomerase I [Streptomyces ochraceiscleroticus].	23.26	589	339	21	2	530	14	549	2e-12	81.3
rs:WP_030407664	DNA topoisomerase I [Streptomyces sp. NRRL F-5917].	23.71	603	327	22	2	530	13	556	2e-12	81.3
tr:A0A0D9MNM3_ASPFL	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:KJJ29417.1};	22.60	646	385	24	3	581	7	604	2e-12	80.9
rs:WP_009186409	DNA topoisomerase I [Cecembia lonarensis].	24.63	540	320	20	3	520	5	479	2e-12	80.9
tr:A0A059J2J0_9EURO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.98	618	378	24	3	560	6	585	2e-12	80.9
tr:A0A0A9J692_ARUDO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.58	598	370	25	77	610	3	571	2e-12	80.9
rs:WP_024999384	DNA topoisomerase I [Prevotella falsenii].	21.83	600	383	18	3	580	5	540	2e-12	80.9
tr:A0A076H187_9SYNE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.52	626	373	23	3	572	28	597	2e-12	81.3
rs:WP_022083390	DNA topoisomerase [Bacteroides sp. CAG:144].	25.17	433	263	13	188	596	69	464	2e-12	80.9
rs:WP_009126193	DNA topoisomerase I [Bacteroides fluxus].	23.05	629	387	22	3	604	5	563	2e-12	80.9
rs:WP_011387625	DNA topoisomerase I [Mycoplasma capricolum].	23.17	669	401	29	3	625	4	605	2e-12	80.9
tr:M0V3B8_HORVD	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:MLOC_17646.4};	23.06	373	244	10	258	614	14	359	2e-12	80.5
rs:XP_011577577	PREDICTED: DNA topoisomerase 3-alpha [Aquila chrysaetos canadensis].	24.44	487	293	19	188	634	235	686	2e-12	81.3
rs:WP_029360563	DNA topoisomerase I [Methylobacterium sp. L2-4].	22.30	686	421	27	1	629	1	631	2e-12	81.3
rs:WP_021663473	DNA topoisomerase I [Porphyromonas gingivalis].	23.68	532	335	16	3	520	4	478	2e-12	80.9
rs:WP_044142794	DNA topoisomerase I [Anaplasma phagocytophilum].	24.46	695	406	33	1	639	1	632	2e-12	80.9
rs:WP_024603564	DNA topoisomerase I, partial [Pseudoalteromonas haloplanktis].	22.54	599	389	21	49	614	59	615	2e-12	80.9
rs:WP_011048772	DNA topoisomerase I [Ruegeria pomeroyi].	21.85	595	349	22	1	534	1	540	2e-12	81.3
rs:WP_019036094	DNA topoisomerase I [Prevotella amnii].	24.00	625	374	24	3	596	5	559	2e-12	80.9
rs:WP_004859900	DNA topoisomerase I [Bartonella taylorii].	23.44	691	409	31	1	629	1	633	2e-12	81.3
rs:WP_036859605	DNA topoisomerase I, partial [Prevotella disiens].	34.27	143	76	5	4	135	5	140	2e-12	76.6
rs:WP_017312762	DNA topoisomerase I [Fischerella sp. PCC 9339].	25.75	501	302	14	100	564	82	548	2e-12	80.9
rs:WP_036056444	DNA topoisomerase I [Leptotrichia goodfellowii].	24.96	621	365	24	2	587	4	558	2e-12	80.9
rs:WP_045748677	DNA topoisomerase I [Mycoplasma capricolum].	23.17	669	401	29	3	625	4	605	2e-12	80.9
rs:WP_006710035	DNA topoisomerase, partial [Serratia symbiotica].	26.90	197	128	4	33	219	1	191	2e-12	77.0
rs:XP_011953620	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Ovis aries].	22.39	518	346	17	3	481	5	505	2e-12	80.9
rs:WP_039919895	DNA topoisomerase I, partial [Leptotrichia goodfellowii].	24.92	662	392	26	2	628	4	595	2e-12	80.9
rs:WP_039442045	DNA topoisomerase I [Porphyromonas gulae].	23.68	532	335	16	3	520	4	478	2e-12	80.9
rs:WP_012667988	topoisomerase I [Erwinia pyrifoliae].	22.11	475	312	13	187	633	190	634	2e-12	80.9
rs:WP_031032136	MULTISPECIES: DNA topoisomerase I [Streptomyces].	23.71	603	327	22	2	530	13	556	2e-12	81.3
rs:WP_008274156	DNA topoisomerase I [Cyanothece sp. CCY0110].	23.14	631	363	21	3	572	4	573	2e-12	80.9
tr:A0A094PGW1_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.60	504	277	22	82	530	63	523	2e-12	80.9
rs:WP_013870165	DNA topoisomerase I [Lacinutrix sp. 5H-3-7-4].	24.58	533	329	18	3	521	5	478	2e-12	80.9
rs:WP_007473084	reverse gyrase [Caminibacter mediatlanticus].	24.63	605	340	27	3	574	547	1068	2e-12	81.3
rs:WP_028558260	DNA topoisomerase I [Paenibacillus sp. URHA0014].	22.60	593	376	20	88	636	62	615	2e-12	80.9
rs:WP_007115615	DNA topoisomerase I, partial [Enhydrobacter aerosaccus].	25.47	373	213	12	187	533	241	574	2e-12	80.9
rs:WP_037512036	DNA topoisomerase I [Sphingopyxis sp. LC81].	21.95	665	433	23	1	629	1	615	2e-12	80.9
rs:WP_024596730	DNA topoisomerase I, partial [Pseudoalteromonas haloplanktis].	22.54	599	389	21	49	614	59	615	2e-12	80.5
tr:G0UHE0_9LACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.99	670	402	24	3	629	36	634	2e-12	80.9
rs:XP_004953162	PREDICTED: uncharacterized protein LOC101783673 [Setaria italica].	22.48	636	391	28	39	610	333	930	2e-12	81.3
rs:WP_037775864	DNA topoisomerase I [Streptomyces sp. HPH0547].	23.71	603	327	22	2	530	13	556	2e-12	80.9
rs:WP_018343699	DNA topoisomerase I [Cytophaga aurantiaca].	24.27	379	246	8	157	520	132	484	2e-12	80.9
rs:WP_005261741	DNA topoisomerase I [Acinetobacter sp. CIP 101966].	23.37	475	294	14	187	629	212	648	2e-12	80.9
rs:WP_008637200	DNA topoisomerase I [Bizionia argentinensis].	24.25	532	331	18	3	521	5	477	2e-12	80.9
tr:Q8RPV4_STRSL	SubName: Full=Topoisomerase {ECO:0000313|EMBL:AAL83958.1}; Flags: Fragment;	26.18	275	179	9	374	625	3	276	2e-12	79.3
rs:WP_021799565	DNA topoisomerase I [Anaplasma phagocytophilum].	24.46	695	406	33	1	639	1	632	2e-12	80.9
tr:S6VCH0_PSESF	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EPN65471.1}; Flags: Fragment;	37.21	129	66	3	86	205	1	123	2e-12	77.0
tr:G3NY50_GASAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.69	498	285	19	188	634	210	663	2e-12	80.9
rs:WP_040314066	hypothetical protein, partial [Bacteriovorax sp. BAL6_X].	24.55	554	333	18	83	587	136	653	2e-12	80.9
rs:WP_008303258	topoisomerase I [Acinetobacter sp. HA].	25.60	375	224	13	187	541	212	551	2e-12	80.9
rs:WP_017933258	DNA topoisomerase I [Nocardioides sp. Iso805N].	22.28	606	319	24	2	528	4	536	2e-12	80.9
gpu:CP007602_8	DNA topoisomerase 3 [Staphylococcus capitis subsp. capitis]	23.53	561	345	22	74	590	110	630	2e-12	80.5
rs:XP_004259792	DNA topoisomerase 3-alpha, putative [Entamoeba invadens IP1].	22.33	636	392	21	3	587	6	590	2e-12	80.5
rs:WP_024864222	DNA topoisomerase I [Bartonella doshiae].	22.43	758	450	33	1	686	1	692	2e-12	80.9
rs:WP_041437548	DNA topoisomerase I, partial [Synechococcus sp. JA-2-3B'a(2-13)].	21.55	631	365	20	2	564	3	571	2e-12	80.9
rs:WP_015774906	DNA topoisomerase I [Desulfomicrobium baculatum].	23.05	564	365	17	77	610	54	578	2e-12	80.9
tr:A0A077KUW3_ACIGI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.40	594	370	19	74	629	102	648	2e-12	80.9
rs:WP_004022112	DNA topoisomerase I [Gordonia terrae].	24.28	589	337	21	2	530	16	555	2e-12	80.9
rs:WP_027300609	DNA topoisomerase I [Rhodospirillales bacterium URHD0088].	23.27	692	409	31	1	630	1	632	2e-12	80.9
rs:WP_033196594	DNA topoisomerase III, partial [Bacillus oceanisediminis].	26.99	289	163	11	381	654	1	256	2e-12	78.2
tr:T0DM55_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.55	554	333	18	83	587	131	648	2e-12	80.9
rs:WP_021890495	DNA topoisomerase [Succinatimonas sp. CAG:777].	22.44	557	379	12	74	612	74	595	2e-12	80.9
rs:WP_041151453	DNA topoisomerase I [Sulfurovum sp. FS08-3].	22.86	665	408	22	3	629	4	601	2e-12	80.9
rs:WP_012083127	reverse gyrase [Nitratiruptor sp. SB155-2].	23.02	530	309	19	79	579	652	1111	2e-12	80.9
rs:WP_029584712	DNA topoisomerase I [Bradyrhizobium sp. URHD0069].	23.46	699	400	33	1	630	1	633	2e-12	80.9
rs:WP_015385507	reverse gyrase [Sulfolobus acidocaldarius].	23.54	514	293	16	78	536	728	1196	2e-12	81.3
tr:A0A017SMB4_9EURO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.83	644	380	27	3	577	5	600	2e-12	80.5
tr:T0L751_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.96	626	393	24	83	666	67	651	2e-12	80.9
rs:WP_028685782	DNA topoisomerase I [Phaseolibacter flectens].	23.06	477	305	15	187	633	190	634	2e-12	80.9
tr:A0A087GIK5_ARAAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.30	392	244	17	32	396	462	839	2e-12	80.9
tr:A0A087GIK7_ARAAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.30	392	244	17	32	396	463	840	2e-12	80.9
rs:XP_749401	DNA topoisomerase III [Aspergillus fumigatus Af293].	22.36	635	384	22	3	573	7	596	2e-12	80.5
tr:J1JDU2_BARDO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.20	694	407	30	1	629	17	649	2e-12	80.9
tr:M0WQP3_HORVD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.07	639	394	23	3	585	11	601	2e-12	80.9
rs:WP_045458631	DNA topoisomerase I [Sporocytophaga myxococcoides].	23.46	537	329	15	3	520	5	478	2e-12	80.9
rs:WP_028083163	DNA topoisomerase I [Dolichospermum circinale].	22.60	615	390	20	3	574	4	575	2e-12	80.9
rs:WP_030615889	DNA topoisomerase I [Streptomyces sclerotialus].	23.87	595	328	22	2	530	14	549	2e-12	80.9
tr:Q14PN0_SPICI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.82	634	402	23	38	643	24	604	3e-12	80.5
rs:WP_022439538	DNA topoisomerase [Clostridium sp. CAG:411].	22.72	559	363	19	90	616	67	588	3e-12	80.5
tr:K7IZC3_NASVI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.02	587	347	25	46	587	58	590	3e-12	80.9
tr:B1H2R2_XENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.74	455	297	16	3	426	5	440	3e-12	80.1
rs:WP_005220842	DNA topoisomerase I [Acinetobacter sp. CIP 101934].	23.79	475	292	16	187	629	212	648	3e-12	80.9
tr:A0A087GIK6_ARAAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.30	392	244	17	32	396	467	844	3e-12	80.9
tr:U6KJS5_EIMTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.70	489	319	16	105	564	139	597	3e-12	80.9
rs:WP_017461890	DNA topoisomerase I [Dyella ginsengisoli].	23.65	482	291	15	103	538	80	530	3e-12	80.9
rs:WP_022846988	reverse gyrase [Desulfurobacterium sp. TC5-1].	23.66	524	311	15	82	579	714	1174	3e-12	80.9
tr:E1G0B3_LOALO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.87	419	260	15	188	585	213	593	3e-12	80.9
rs:XP_010674423	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Beta vulgaris subsp. vulgaris].	23.75	421	262	13	188	585	216	600	3e-12	80.9
rs:WP_036914349	DNA topoisomerase I [Prevotella sp. FD3004].	22.46	601	372	18	3	580	5	534	3e-12	80.5
rs:WP_033386012	topoisomerase I, partial [Lactobacillus suebicus].	26.38	163	118	1	432	592	16	178	3e-12	77.8
rs:WP_009379579	DNA topoisomerase I [Bilophila sp. 4_1_30].	22.77	571	369	19	76	614	53	583	3e-12	80.5
rs:WP_025024322	DNA topoisomerase I [Lactobacillus nodensis].	22.58	682	406	26	3	635	8	616	3e-12	80.5
rs:WP_025902260	DNA topoisomerase I, partial [Tatumella sp. UCD-D_suzukii].	22.92	445	285	13	187	614	12	415	3e-12	80.1
tr:B9EZZ0_ORYSJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.80	614	370	26	64	610	198	774	3e-12	80.9
gpu:CP009516_1332	DNA topoisomerase I [Methanosarcina horonobensis HB-1]	22.61	637	399	26	21	611	27	615	3e-12	80.9
rs:WP_044111856	DNA topoisomerase I [Acinetobacter sp. MII].	23.37	475	294	14	187	629	212	648	3e-12	80.9
tr:A0A098ED90_9ZZZZ	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:CEG13983.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEG13983.1};	28.03	289	185	9	145	417	15	296	3e-12	78.6
tr:W5E075_WHEAT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.03	640	393	24	3	585	11	601	3e-12	80.9
tr:D4X879_9BURK	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:EFF77009.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFF77009.1};	26.09	230	165	3	380	604	240	469	3e-12	79.7
tr:M0WQP4_HORVD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.07	639	394	23	3	585	11	601	3e-12	80.9
rs:WP_004278474	topoisomerase I [Acinetobacter lwoffii].	23.37	475	294	14	187	629	212	648	3e-12	80.9
tr:W9CLG8_9HELO	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ESZ97647.1};	23.93	560	344	23	3	520	6	525	3e-12	80.5
rs:WP_011277708	reverse gyrase [Sulfolobus acidocaldarius].	23.54	514	293	16	78	536	531	999	3e-12	80.9
sp:RGYR_SULAC	RecName: Full=Reverse gyrase {ECO:0000255|HAMAP-Rule:MF_01125}; Includes: RecName: Full=Helicase {ECO:0000255|HAMAP-Rule:MF_01125}; EC=3.6.4.12 {ECO:0000255|HAMAP-Rule:MF_01125}; Includes: RecName: Full=Topoisomerase {ECO:0000255|HAMAP-Rule:MF_01125}; EC=5.99.1.3 {ECO:0000255|HAMAP-Rule:MF_01125};	23.54	514	293	16	78	536	731	1199	3e-12	80.9
rs:WP_018477788	DNA topoisomerase I [Pontibacter roseus].	22.85	547	353	15	74	596	51	552	3e-12	80.5
rs:WP_042743747	DNA topoisomerase III, partial [Staphylococcus aureus].	34.72	144	74	4	3	135	4	138	3e-12	75.9
rs:WP_025159114	DNA topoisomerase I [Leifsonia aquatica].	24.24	590	332	23	2	530	6	541	3e-12	80.9
tr:T5BWA9_AJEDE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.79	638	409	21	3	586	6	607	3e-12	80.5
rs:WP_014939949	DNA topoisomerase I [Lactobacillus buchneri].	22.54	559	364	20	103	629	101	622	3e-12	80.5
rs:WP_014584532	DNA topoisomerase I [Mycoplasma leachii].	22.88	625	382	26	46	625	36	605	3e-12	80.5
rs:WP_004890309	DNA topoisomerase I [Acinetobacter schindleri].	23.79	475	292	16	187	629	212	648	3e-12	80.9
tr:J6XCY2_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EJX43826.1}; Flags: Fragment;	33.08	133	84	2	65	192	13	145	3e-12	75.9
rs:WP_028118478	DNA topoisomerase I [Facklamia sourekii].	24.82	560	348	25	103	629	81	600	3e-12	80.5
rs:XP_010674422	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Beta vulgaris subsp. vulgaris].	23.75	421	262	13	188	585	216	600	3e-12	80.9
rs:WP_009597583	DNA topoisomerase I [Alistipes sp. HGB5].	23.61	466	307	15	77	526	54	486	3e-12	80.5
rs:WP_024499534	DNA topoisomerase I [Gordonia amicalis].	24.33	596	325	23	2	530	16	552	3e-12	80.9
rs:WP_006642029	DNA topoisomerase I [Brucella ceti].	22.61	690	415	29	1	629	1	632	3e-12	80.5
rs:WP_032070408	DNA topoisomerase I [Acinetobacter baumannii].	22.47	574	368	17	90	629	116	646	3e-12	80.5
rs:WP_012566718	DNA topoisomerase I [Rhodospirillum centenum].	22.40	634	409	23	55	630	30	638	3e-12	80.9
rs:WP_010214857	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	26.14	176	119	4	1	173	1	168	3e-12	76.3
rs:WP_010777295	hypothetical protein [Enterococcus faecium].	37.07	116	61	3	3	111	4	114	3e-12	75.1
rs:WP_018966009	DNA topoisomerase I [Porphyromonas gulae].	23.73	531	335	15	3	520	4	477	3e-12	80.5
tr:A0A069YQP7_ECOLX	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:KDU49610.1};	34.10	173	101	5	497	663	11	176	3e-12	77.0
rs:WP_014066714	DNA topoisomerase I [Rhodothermus marinus].	23.65	575	353	19	2	530	3	537	3e-12	80.5
rs:WP_014934419	DNA topoisomerase I [Cardinium endosymbiont of Encarsia pergandiella].	24.28	519	331	13	77	578	54	527	3e-12	80.5
tr:A0A090WSL8_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.60	378	249	10	154	521	53	404	3e-12	80.5
rs:WP_020087305	DNA topoisomerase I [Hyphomicrobium zavarzinii].	22.94	606	367	24	36	586	20	580	3e-12	80.5
rs:WP_042086403	DNA topoisomerase I [alpha proteobacterium Q-1].	23.72	662	410	25	55	656	27	653	3e-12	80.5
rs:WP_006661659	DNA topoisomerase III [Providencia alcalifaciens].	34.82	112	63	4	1	108	1	106	3e-12	75.1
tr:D0GKB0_9FUSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.96	621	365	24	2	587	17	571	3e-12	80.5
rs:WP_010229101	DNA topoisomerase I [Chlamydia muridarum].	21.99	664	396	23	3	612	5	600	3e-12	80.5
tr:A0A0E0CKE4_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OMERI02G16280.3};	22.56	634	374	26	39	610	310	888	3e-12	80.9
rs:WP_011314971	DNA topoisomerase I [Nitrobacter winogradskyi].	23.45	725	426	31	1	659	1	662	3e-12	80.5
rs:WP_022414726	DNA topoisomerase [Clostridium sp. CAG:288].	24.01	683	379	28	1	630	1	596	3e-12	80.5
rs:WP_005007267	DNA topoisomerase I [Acinetobacter bouvetii].	23.64	478	289	16	187	629	211	647	3e-12	80.5
rs:WP_043073258	DNA topoisomerase I [Methylobacterium radiotolerans].	22.30	686	421	27	1	629	1	631	3e-12	80.5
rs:WP_011753872	DNA topoisomerase I [Nocardioides sp. JS614].	23.22	633	378	25	2	577	4	585	3e-12	80.5
rs:WP_036819223	DNA topoisomerase I, partial [Piscirickettsia salmonis].	23.25	585	376	21	88	630	66	619	3e-12	80.5
rs:WP_034043528	DNA topoisomerase I [Flaviramulus ichthyoenteri].	25.72	381	239	11	154	521	128	477	3e-12	80.5
rs:WP_011329011	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	35.96	114	59	4	1	108	1	106	3e-12	75.1
rs:WP_039434731	DNA topoisomerase I [Porphyromonas gulae].	23.73	531	335	15	3	520	4	477	3e-12	80.5
rs:WP_036365716	DNA topoisomerase I [Moraxella bovoculi].	22.41	580	386	17	77	629	102	644	3e-12	80.5
tr:M0WQP1_HORVD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.07	639	394	23	3	585	11	601	3e-12	80.5
rs:WP_030483292	DNA topoisomerase I [Marmoricola aequoreus].	21.73	672	400	23	2	602	4	620	3e-12	80.5
rs:WP_021148177	DNA topoisomerase I [Veillonella parvula].	22.93	580	353	23	95	629	142	672	3e-12	80.5
rs:WP_008193600	DNA topoisomerase I [Labrenzia alexandrii].	23.57	628	365	25	1	574	1	567	3e-12	80.5
rs:WP_019490681	DNA topoisomerase I [Calothrix sp. PCC 7103].	23.48	609	364	20	3	560	4	561	3e-12	80.5
rs:WP_027305561	DNA topoisomerase I [Campylobacter cuniculorum].	23.17	656	388	23	3	618	5	584	3e-12	80.5
rs:WP_005194610	DNA topoisomerase I [Gordonia rubripertincta].	24.87	587	333	23	2	530	16	552	3e-12	80.5
tr:A8PGM1_BRUMA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.04	676	424	25	3	629	7	628	3e-12	80.5
rs:WP_013951507	DNA topoisomerase I [Candidatus Midichloria mitochondrii].	22.91	563	357	17	1	534	1	515	3e-12	80.5
rs:WP_027880536	DNA topoisomerase I [Mesoflavibacter zeaxanthinifaciens].	24.43	528	335	18	3	521	5	477	3e-12	80.5
rs:WP_036278948	DNA topoisomerase I [Microbacterium sp. CH12i].	23.34	604	328	24	2	538	6	541	3e-12	80.5
rs:WP_045169780	reverse gyrase [Caldicellulosiruptor sp. Rt8.B8].	23.97	484	265	17	81	536	660	1068	3e-12	80.5
tr:Q2JJ84_SYNJB	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.55	631	365	20	2	564	3	571	3e-12	80.5
rs:WP_016226244	hypothetical protein [Lachnospiraceae bacterium 3-2].	33.64	110	65	3	1	107	1	105	3e-12	74.7
rs:WP_005029320	DNA topoisomerase I [Bilophila wadsworthia].	22.77	571	369	19	76	614	53	583	3e-12	80.5
rs:WP_027242705	DNA topoisomerase I [Piscirickettsia salmonis].	24.74	481	300	17	88	533	66	519	3e-12	80.5
rs:WP_024581368	MULTISPECIES: DNA topoisomerase I [Bradyrhizobium].	22.82	688	417	28	1	630	1	632	3e-12	80.5
tr:K3WHB4_PYTUL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblProtists:PYU1_T004356};	22.08	643	395	25	1	585	1	595	3e-12	80.5
rs:WP_020095334	DNA topoisomerase I [Methylobacterium sp. 285MFTsu5.1].	22.45	686	420	27	1	629	1	631	3e-12	80.5
rs:WP_029485813	topoisomerase, partial [Enterococcus faecium].	37.29	118	62	3	3	113	4	116	3e-12	75.1
tr:L3QGS2_ECOLX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELE59473.1};	33.06	124	83	0	462	585	6	129	3e-12	75.5
rs:WP_007655144	DNA topoisomerase I [Parabacteroides goldsteinii].	23.45	563	345	19	3	541	5	505	3e-12	80.5
rs:XP_001605592	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Nasonia vitripennis].	24.02	587	347	25	46	587	102	634	3e-12	80.5
rs:WP_017506494	DNA topoisomerase I [alpha proteobacterium L41A].	22.12	556	343	20	1	520	1	502	3e-12	80.5
rs:WP_028951357	DNA topoisomerase I [Synechococcus sp. CC9616].	22.97	627	369	25	3	572	5	574	3e-12	80.5
rs:WP_042506432	DNA topoisomerase I [Algibacter lectus].	24.67	377	249	10	154	521	128	478	3e-12	80.5
rs:XP_002465810	hypothetical protein SORBIDRAFT_01g046210 [Sorghum bicolor].	22.75	633	397	25	3	585	12	602	3e-12	80.5
rs:WP_042669667	DNA topoisomerase I [Methylobacterium sp. B34].	22.45	686	420	27	1	629	1	631	3e-12	80.5
rs:WP_040223164	DNA topoisomerase III, partial [Klebsiella pneumoniae].	26.96	293	146	10	446	673	23	312	3e-12	78.2
rs:WP_014775458	DNA topoisomerase I [Alistipes finegoldii].	23.66	465	306	15	77	525	54	485	3e-12	80.5
tr:N8LPK6_BRUOV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.58	691	414	29	1	629	10	641	3e-12	80.5
rs:WP_039883879	DNA topoisomerase III, partial [Achromobacter piechaudii].	27.94	204	143	2	382	581	1	204	3e-12	77.0
rs:WP_032825813	topoisomerase I, partial [Oenococcus oeni].	25.84	209	133	5	293	489	3	201	3e-12	77.0
tr:K8DAB0_9ENTR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CCK14063.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CCK14063.1};	38.54	96	59	0	486	581	8	103	3e-12	75.9
rs:WP_009230497	DNA topoisomerase I [Prevotella sp. oral taxon 317].	23.15	553	330	17	3	526	5	491	3e-12	80.5
tr:M1X6L7_9NOST	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.31	632	377	19	3	574	33	610	3e-12	80.5
rs:WP_040556917	DNA topoisomerase I [Prevotella nigrescens].	21.70	599	385	17	3	580	5	540	3e-12	80.5
rs:XP_005694304	PREDICTED: DNA topoisomerase 3-alpha [Capra hircus].	23.48	494	288	18	188	634	309	759	3e-12	80.5
rs:WP_046697158	DNA topoisomerase I [Moraxella bovoculi].	22.66	587	376	20	77	629	102	644	3e-12	80.5
rs:WP_034454831	DNA topoisomerase I [Bartonella henselae].	22.78	698	405	29	1	629	1	633	3e-12	80.5
gpu:CP009507_2218	DNA topoisomerase I [Methanosarcina siciliae HI350]	22.64	636	400	26	21	611	27	615	3e-12	80.5
rs:WP_044010110	DNA topoisomerase I [Lactobacillus sp. WDC04].	23.33	570	372	21	90	629	88	622	3e-12	80.1
rs:WP_011949980	DNA topoisomerase I [Brucella ovis].	22.33	694	412	29	1	629	1	632	3e-12	80.5
rs:WP_003609775	DNA topoisomerase I [Methylosinus trichosporium].	23.31	652	400	28	38	630	22	632	3e-12	80.5
rs:WP_023454501	DNA topoisomerase I [Asticcacaulis sp. AC460].	21.29	681	430	25	1	629	1	627	3e-12	80.5
rs:WP_012895567	DNA topoisomerase I [Streptosporangium roseum].	23.36	608	312	25	2	530	12	544	3e-12	80.5
rs:WP_007709436	DNA topoisomerase I, partial [Sphingobium sp. AP49].	24.76	412	250	14	1	392	1	372	3e-12	79.0
tr:F9DBT9_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.70	599	385	17	3	580	24	559	3e-12	80.1
tr:A0A091R088_9GRUI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.51	408	257	15	188	577	134	508	3e-12	80.5
rs:WP_032444896	DNA topoisomerase III, partial [Klebsiella pneumoniae].	26.96	293	146	10	446	673	67	356	3e-12	78.6
rs:XP_010180235	PREDICTED: DNA topoisomerase 3-alpha, partial [Mesitornis unicolor].	24.51	408	257	15	188	577	152	526	3e-12	80.5
rs:WP_026385425	DNA topoisomerase I [Acidaminococcus intestini].	21.45	648	412	18	3	616	4	588	3e-12	80.1
tr:E6QED7_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CBI05563.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI05563.1};	22.61	513	333	18	154	630	13	497	3e-12	80.1
rs:WP_028902877	DNA topoisomerase I [Prevotella sp. P6B4].	22.73	550	332	20	3	526	5	487	3e-12	80.1
rs:WP_044304979	DNA topoisomerase I [Richelia intracellularis].	22.31	632	377	19	3	574	4	581	3e-12	80.5
rs:WP_012318007	DNA topoisomerase I [Methylobacterium radiotolerans].	21.87	686	424	25	1	629	1	631	3e-12	80.5
rs:WP_026935201	DNA topoisomerase I [Gramella echinicola].	26.96	382	233	15	154	521	128	477	3e-12	80.1
rs:WP_033166717	DNA topoisomerase I [Clostridium sp. KNHs205].	22.94	632	377	21	90	671	65	636	3e-12	80.1
rs:WP_014397849	DNA topoisomerase I [Corallococcus coralloides].	22.06	689	430	27	3	640	85	717	4e-12	80.5
rs:WP_020285757	DNA topoisomerase I [Osedax symbiont Rs2].	22.81	605	365	22	72	629	86	635	4e-12	80.5
rs:WP_022455371	DNA topoisomerase [Parabacteroides sp. CAG:409].	29.65	199	106	6	486	651	1	198	4e-12	76.6
rs:WP_006641755	MULTISPECIES: DNA topoisomerase I [Brucella].	22.61	690	415	29	1	629	1	632	4e-12	80.5
rs:WP_037153652	DNA topoisomerase I [Rhizobium freirei].	21.85	659	412	25	38	630	16	637	4e-12	80.5
rs:XP_008393933	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X2 [Malus domestica].	22.81	526	311	21	157	618	41	535	4e-12	80.1
rs:WP_012308141	DNA topoisomerase I [Synechococcus sp. PCC 7002].	23.86	616	361	21	3	564	4	565	4e-12	80.1
rs:WP_033147559	DNA topoisomerase I [Prevotella sp. P6B1].	22.73	550	332	20	3	526	5	487	4e-12	80.1
rs:XP_008203893	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Nasonia vitripennis].	24.02	587	347	25	46	587	76	608	4e-12	80.5
rs:XP_003682560	hypothetical protein TDEL_0F05380 [Torulaspora delbrueckii].	23.14	644	379	23	3	567	4	610	4e-12	80.1
tr:V5GCH8_BYSSN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.98	637	407	22	3	584	6	607	4e-12	79.7
rs:XP_009850867	hypothetical protein NEUTE1DRAFT_81659 [Neurospora tetrasperma FGSC 2508].	22.87	564	346	22	3	521	5	524	4e-12	80.1
rs:WP_033851504	DNA topoisomerase III, partial [Staphylococcus aureus].	37.50	136	72	5	3	133	4	131	4e-12	75.1
rs:WP_011620028	DNA topoisomerase I [Synechococcus sp. CC9311].	23.63	567	330	20	3	519	5	518	4e-12	80.1
rs:WP_007834608	DNA topoisomerase I [Bacteroides dorei].	24.56	562	353	19	77	617	54	565	4e-12	80.1
tr:A0A059ELY1_9MICR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KCZ75726.1}; Flags: Fragment;	23.54	497	332	12	93	573	32	496	4e-12	79.7
rs:WP_028735946	DNA topoisomerase I [Rhizobium selenitireducens].	21.97	692	422	30	1	630	1	636	4e-12	80.1
rs:WP_033742789	DNA topoisomerase I [Helicobacter pylori].	22.97	640	401	24	3	614	4	579	4e-12	80.1
rs:WP_016858466	DNA topoisomerase I [Fischerella muscicola].	25.55	501	303	14	100	564	82	548	4e-12	80.1
rs:WP_019221809	DNA topoisomerase I [Bartonella senegalensis].	23.07	698	403	29	1	629	1	633	4e-12	80.1
rs:WP_013909051	topoisomerase [Thermodesulfobacterium geofontis].	24.75	509	296	18	82	564	705	1152	4e-12	80.5
tr:N1J751_BLUG1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.16	583	355	22	3	535	5	544	4e-12	80.1
rs:WP_031528031	DNA topoisomerase I [Dyadobacter crusticola].	24.29	457	301	12	77	520	54	478	4e-12	80.1
rs:WP_028729778	DNA topoisomerase I [Parabacteroides gordonii].	23.38	539	330	17	3	520	5	481	4e-12	80.1
tr:N6V4J9_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.94	661	409	25	38	630	17	638	4e-12	80.1
tr:I1H9D9_BRADI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.47	632	400	23	3	585	14	604	4e-12	80.1
tr:W5E6N9_WHEAT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.82	425	261	14	188	585	186	570	4e-12	80.1
rs:WP_022043898	DNA topoisomerase [Alistipes finegoldii CAG:68].	24.73	469	296	18	77	525	54	485	4e-12	80.1
rs:WP_021965327	DNA topoisomerase [Prevotella sp. CAG:1185].	22.86	560	343	16	3	540	5	497	4e-12	80.1
rs:WP_046148222	DNA topoisomerase I [Parabacteroides sp. HGS0025].	23.38	539	330	17	3	520	5	481	4e-12	80.1
rs:WP_029195346	DNA topoisomerase I [Paenibacillus alginolyticus].	22.77	593	375	21	88	636	62	615	4e-12	80.1
rs:WP_036499076	DNA topoisomerase I, partial [Mycoplasma testudinis].	21.72	640	399	25	70	649	52	649	4e-12	80.1
rs:WP_044017930	DNA topoisomerase I [Hymenobacter sp. APR13].	23.80	479	291	13	74	521	51	486	4e-12	80.1
rs:WP_031426006	DNA topoisomerase I [Leeuwenhoekiella sp. MAR_2009_132].	23.34	664	389	20	3	618	5	596	4e-12	80.1
rs:XP_008203894	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Nasonia vitripennis].	24.02	587	347	25	46	587	8	540	4e-12	80.5
tr:A0A075HJB3_9EURY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.85	534	328	19	88	581	33	522	4e-12	80.1
rs:WP_011180711	DNA topoisomerase I [Bartonella henselae].	22.78	698	405	29	1	629	1	633	4e-12	80.1
tr:B8AHL0_ORYSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.54	621	373	25	64	612	198	782	4e-12	80.1
tr:A0A0B0HVB4_9BACL	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:KHF32527.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KHF32527.1};	25.50	251	156	5	374	615	6	234	4e-12	78.2
rs:WP_010196278	topoisomerase I [Psychrobacter sp. PAMC 21119].	24.06	586	376	20	77	629	100	649	4e-12	80.1
tr:A0A084BGY4_ASPFM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.36	635	384	22	3	573	7	596	4e-12	79.7
rs:WP_014440449	DNA topoisomerase I [Actinoplanes missouriensis].	23.70	637	364	25	2	571	9	590	4e-12	80.1
gpu:CP009506_2210	DNA topoisomerase I [Methanosarcina siciliae T4/M]	22.64	636	400	26	21	611	27	615	4e-12	80.1
rs:WP_039247669	DNA topoisomerase I [Brevundimonas nasdae].	21.94	556	344	20	1	520	1	502	4e-12	80.1
rs:WP_026813116	DNA topoisomerase I [Arenibacter certesii].	24.81	532	330	16	3	521	5	479	4e-12	80.1
tr:G4FJ28_9SYNE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.73	566	342	17	3	519	28	541	4e-12	80.1
gp:CP006897_535	DNA topoisomerase I [Brucella ceti TE10759-12]	22.61	690	415	29	1	629	10	641	4e-12	80.1
rs:WP_014262163	DNA topoisomerase I [Filifactor alocis].	23.22	547	310	19	157	640	133	632	4e-12	79.7
tr:A0A068FQU3_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:AID69676.1};	21.40	701	416	29	1	630	1	637	4e-12	80.1
rs:WP_034077591	DNA topoisomerase I [Pseudomonas aeruginosa].	22.79	588	366	19	80	631	54	589	4e-12	79.7
rs:WP_035860044	DNA topoisomerase I [Cryptosporangium arvum].	22.56	665	345	30	1	571	1	589	4e-12	80.1
rs:WP_002339153	hypothetical protein [Enterococcus faecium].	35.90	117	63	3	3	112	4	115	4e-12	74.7
tr:E6NGC0_HELPK	SubName: Full=Topoisomerase I {ECO:0000313|EMBL:BAJ57303.1};	27.72	267	163	9	75	317	46	306	4e-12	77.8
tr:J5UYF0_ENTFC	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EJX43737.1}; Flags: Fragment;	26.90	171	122	1	347	514	27	197	4e-12	76.3
rs:WP_012821484	DNA topoisomerase I [Blattabacterium sp. (Periplaneta americana)].	27.61	355	226	12	39	385	25	356	4e-12	79.7
rs:WP_012864401	DNA topoisomerase I [Veillonella parvula].	22.57	567	371	22	95	629	142	672	4e-12	80.1
rs:XP_007425113	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Python bivittatus].	23.40	483	303	17	188	634	176	627	4e-12	80.1
tr:W1Q971_OGAPD	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:ESW97356.1}; EC=5.99.1.2 {ECO:0000313|EMBL:ESW97356.1};	21.36	674	407	20	3	601	4	629	4e-12	79.7
tr:Q08Q69_STIAD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.22	534	332	20	76	560	119	623	4e-12	80.1
tr:J7AQD8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.42	258	180	3	250	497	11	263	4e-12	77.0
rs:NP_001085699	topoisomerase (DNA) III alpha [Xenopus laevis].	23.17	492	293	17	188	634	244	695	4e-12	80.1
tr:A0A0D9MAX8_9EURO	SubName: Full=DNA topoisomerase type IA DNA-binding {ECO:0000313|EMBL:KJJ24901.1};	24.56	623	359	25	3	560	6	582	4e-12	79.7
rs:WP_030635107	DNA topoisomerase I [Streptomyces rimosus].	23.79	597	326	22	2	530	14	549	4e-12	80.1
tr:A0A0D2GQU9_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.61	576	357	23	79	612	55	589	4e-12	79.7
rs:WP_038556453	DNA topoisomerase I [Synechococcus sp. KORDI-52].	22.36	626	374	24	3	572	5	574	5e-12	80.1
rs:WP_011139337	DNA topoisomerase I [Wolinella succinogenes].	23.07	659	411	23	3	629	4	598	5e-12	79.7
rs:WP_023444285	hypothetical protein [Pseudomonas chloritidismutans].	22.31	484	305	15	163	616	134	576	5e-12	79.7
tr:H2SSS8_TAKRU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.98	496	291	19	188	634	210	663	5e-12	80.1
rs:WP_013546559	DNA topoisomerase I [Bacteroides helcogenes].	22.92	637	378	21	3	604	5	563	5e-12	79.7
tr:S3ANX1_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.08	573	317	21	32	530	14	542	5e-12	80.1
rs:WP_006359050	DNA topoisomerase I [Gordonia alkanivorans].	24.87	587	333	23	2	530	16	552	5e-12	80.1
rs:WP_039316996	DNA topoisomerase I [Clostridium baratii].	22.12	669	410	23	2	629	4	602	5e-12	79.7
tr:C9M7U6_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.53	576	360	17	88	615	46	577	5e-12	79.7
tr:A0A098LAU1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.35	460	297	10	77	520	21	445	5e-12	79.7
rs:XP_002672722	predicted protein [Naegleria gruberi].	23.30	412	225	15	188	560	233	592	5e-12	80.1
tr:M5TW19_9PLAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.20	582	338	16	3	530	9	535	5e-12	80.1
rs:XP_003964491	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Takifugu rubripes].	22.98	496	291	19	188	634	255	708	5e-12	80.1
rs:WP_019187748	DNA topoisomerase I [Candidatus Prevotella conceptionensis].	23.60	555	325	19	3	526	5	491	5e-12	79.7
rs:WP_034901041	DNA topoisomerase I [Erythrobacter litoralis].	22.26	656	400	23	1	610	1	592	5e-12	79.7
rs:XP_011602049	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Takifugu rubripes].	22.98	496	291	19	188	634	214	667	5e-12	80.1
rs:WP_010780938	DNA topoisomerase 1 [Enterococcus gilvus].	24.96	589	357	25	90	635	68	614	5e-12	79.7
tr:K7GGM4_PELSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.71	485	299	18	188	634	241	692	5e-12	80.1
rs:WP_046699395	DNA topoisomerase I [Moraxella bovoculi].	22.28	588	377	18	77	629	102	644	5e-12	79.7
rs:XP_010229156	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Brachypodium distachyon].	22.47	632	400	23	3	585	14	604	5e-12	80.1
tr:J7T930_CLOSG	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.09	660	379	26	3	616	9	592	5e-12	79.7
tr:J9DEH1_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.30	558	335	21	1	520	1	503	5e-12	79.7
rs:WP_038300223	DNA topoisomerase I, partial [alpha proteobacterium IMCC14465].	23.30	558	335	21	1	520	1	503	5e-12	79.7
rs:WP_024071642	DNA topoisomerase I [Mycoplasma ovis].	23.32	639	404	19	90	679	73	674	5e-12	79.7
tr:G8BAX5_CANPC	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:CCE42199.1};	22.06	621	397	19	3	574	4	586	5e-12	79.3
tr:Q877H4_9CREN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.03	396	213	16	219	585	22	374	5e-12	79.0
rs:WP_038013874	DNA topoisomerase I [Synechococcus sp. WH 8016].	21.73	566	342	17	3	519	5	518	5e-12	79.7
rs:WP_019226964	MULTISPECIES: DNA topoisomerase I [Clostridiales].	22.83	565	361	20	103	629	79	606	5e-12	79.7
gp:CP002744_994	DNA topoisomerase I/SWI domain fusion protein [Chlamydia psittaci Mat116]	23.05	616	338	23	157	670	3	584	5e-12	79.7
rs:XP_007448453	PREDICTED: DNA topoisomerase 3-alpha [Lipotes vexillifer].	23.29	498	285	19	188	634	239	690	5e-12	80.1
tr:F3HNN0_PSEYM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGH60950.1};	31.13	151	94	4	54	197	12	159	5e-12	75.9
rs:WP_029657274	hypothetical protein, partial [Enterococcus faecalis].	38.60	114	66	3	3	113	4	116	5e-12	74.3
tr:K7GGN4_PELSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.71	485	299	18	188	634	241	692	5e-12	80.1
tr:H3B0D1_LATCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.58	607	397	19	3	564	5	577	5e-12	79.7
rs:WP_023926303	DNA topoisomerase I [Prevotella nigrescens].	21.54	599	386	17	3	580	5	540	5e-12	79.7
rs:WP_032818902	topoisomerase I, partial [Oenococcus oeni].	26.27	255	165	8	424	664	3	248	5e-12	77.0
rs:WP_005172815	DNA topoisomerase I [Acinetobacter sp. NIPH 713].	24.53	375	228	11	187	541	212	551	5e-12	79.7
tr:Q3EKS1_BACTI	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EAO51911.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EAO51911.1};	30.70	215	111	5	467	655	11	213	5e-12	76.6
rs:XP_011683116	PREDICTED: DNA topoisomerase 3-beta-1 [Strongylocentrotus purpuratus].	23.77	387	253	13	188	560	115	473	5e-12	79.7
rs:WP_041051039	DNA topoisomerase I [Helicobacter pylori].	23.34	467	307	12	99	537	77	520	5e-12	79.3
rs:WP_011917108	reverse gyrase [Caldicellulosiruptor saccharolyticus].	23.57	488	262	16	81	536	662	1070	5e-12	80.1
rs:WP_006010019	DNA topoisomerase I [Ehrlichia chaffeensis].	23.83	751	439	30	1	684	1	685	5e-12	79.7
rs:WP_044283427	DNA topoisomerase I, partial [Candidatus Endolissoclinum faulkneri].	23.45	614	379	23	3	577	4	565	5e-12	79.7
rs:WP_004066812	DNA topoisomerase I [Thermococcus litoralis].	25.83	333	205	12	3	310	4	319	5e-12	79.7
rs:XP_006126683	PREDICTED: DNA topoisomerase 3-alpha [Pelodiscus sinensis].	23.71	485	299	18	188	634	241	692	5e-12	79.7
rs:XP_007425112	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Python bivittatus].	23.40	483	303	17	188	634	212	663	5e-12	79.7
rs:XP_008667755	PREDICTED: hypothetical protein isoform X1 [Zea mays].	22.31	641	390	25	3	585	12	602	5e-12	79.7
tr:A0A0D9YS71_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OGLUM02G16580.2};	23.09	628	370	28	39	610	309	879	5e-12	79.7
rs:WP_010801879	MULTISPECIES: DNA topoisomerase I [Parabacteroides].	23.28	537	331	17	3	520	5	479	5e-12	79.7
tr:E6YVP5_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.41	692	408	31	1	629	1	633	5e-12	79.7
rs:XP_005504604	PREDICTED: DNA topoisomerase 3-alpha [Columba livia].	24.16	389	255	12	188	564	239	599	5e-12	79.7
tr:A0A087W023_ECHMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.79	661	393	24	35	620	47	658	5e-12	79.7
rs:WP_039532272	DNA topoisomerase I [Ruegeria sp. ANG-S4].	22.34	582	353	21	1	534	1	531	5e-12	79.7
tr:A0A068VC66_COFCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.51	621	357	26	64	610	414	990	5e-12	79.7
rs:WP_010685456	DNA topoisomerase I [Methylobacterium mesophilicum].	21.87	686	424	25	1	629	1	631	5e-12	79.7
rs:WP_029919888	DNA topoisomerase I [Nevskia soli].	24.02	487	304	19	85	533	62	520	5e-12	79.7
tr:K4A5R4_SETIT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.46	641	389	25	3	585	13	603	6e-12	79.7
rs:WP_043895451	DNA topoisomerase I [Porphyromonas gingivalis].	24.35	538	324	19	3	520	4	478	6e-12	79.7
rs:WP_040346999	DNA topoisomerase I [Anaeroglobus geminatus].	23.13	601	365	20	82	631	111	665	6e-12	79.7
rs:WP_011752245	reverse gyrase [Thermofilum pendens].	23.08	559	328	19	82	609	784	1271	6e-12	80.1
rs:WP_022702085	DNA topoisomerase I [Oceanicaulis alexandrii].	21.90	717	385	31	1	630	1	629	6e-12	79.7
rs:WP_008200254	DNA topoisomerase I [Algoriphagus machipongonensis].	25.81	399	245	12	3	392	5	361	6e-12	79.7
rs:WP_043522729	DNA topoisomerase I [Actinoplanes utahensis].	22.91	633	374	24	2	571	9	590	6e-12	79.7
rs:WP_036855184	DNA topoisomerase I [Prevotella amnii].	23.84	625	375	24	3	596	5	559	6e-12	79.7
tr:A0A061RF57_9CHLO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.41	645	390	26	39	619	77	681	6e-12	79.7
rs:XP_007497919	PREDICTED: DNA topoisomerase 3-alpha [Monodelphis domestica].	22.44	468	291	17	188	619	222	653	6e-12	79.7
rs:WP_015496188	DNA topoisomerase I [Octadecabacter arcticus].	22.48	565	352	22	1	534	1	510	6e-12	79.7
rs:WP_034489568	DNA topoisomerase I [Agrobacterium rhizogenes].	22.00	659	411	26	38	630	16	637	6e-12	79.7
tr:J0V077_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.62	580	358	21	3	554	11	533	6e-12	79.3
rs:WP_042385490	MULTISPECIES: DNA topoisomerase I [Clostridium].	24.09	660	379	26	3	616	5	588	6e-12	79.3
rs:WP_017883608	DNA topoisomerase I [Leucobacter sp. UCD-THU].	22.88	590	348	20	2	530	6	549	6e-12	79.7
rs:WP_032505012	hypothetical protein [Streptococcus suis].	39.45	109	54	4	1	104	1	102	6e-12	73.9
rs:WP_042225319	DNA topoisomerase [Leptospirillum sp. Group II 'C75'].	22.81	640	406	28	36	631	6	601	6e-12	79.3
rs:WP_027906307	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	23.64	478	301	15	186	633	194	637	6e-12	79.7
tr:U2LFN4_PORGN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.35	538	324	19	3	520	31	505	6e-12	79.7
rs:WP_024071957	DNA topoisomerase I [Ehrlichia muris].	22.99	748	432	27	1	671	1	681	6e-12	79.7
rs:WP_004855164	DNA topoisomerase I [Acinetobacter gerneri].	23.14	484	284	16	187	629	211	647	6e-12	79.7
rs:WP_002351391	toprim domain protein, partial [Enterococcus faecium].	32.60	181	117	4	3	179	5	184	6e-12	75.9
tr:A0A010PCK1_9MICC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.67	591	347	21	2	530	6	548	6e-12	79.7
tr:B6YQH0_AZOPC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.68	538	354	13	3	530	5	490	6e-12	79.3
rs:WP_007294258	DNA topoisomerase I [delta proteobacterium MLMS-1].	22.70	608	385	19	83	636	60	636	6e-12	79.3
rs:WP_006191226	DNA topoisomerase I [Selenomonas sputigena].	22.26	557	366	18	90	616	180	699	6e-12	79.7
rs:XP_007834111	hypothetical protein PFICI_07339 [Pestalotiopsis fici W106-1].	21.51	558	360	16	3	520	4	523	6e-12	79.3
rs:WP_044171393	DNA topoisomerase I [Flectobacillus major].	24.41	549	348	19	74	600	51	554	6e-12	79.7
tr:K7ZDL5_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.26	619	374	24	3	577	4	565	6e-12	79.7
rs:WP_009237164	DNA topoisomerase I [Prevotella sp. oral taxon 472].	22.90	607	363	19	3	580	5	535	6e-12	79.3
rs:WP_023847008	DNA topoisomerase I [Porphyromonas gingivalis].	24.35	538	324	19	3	520	4	478	6e-12	79.3
tr:A8QH57_BRUMA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.73	472	283	17	188	629	77	501	6e-12	79.3
rs:WP_036901249	DNA topoisomerase I [Prochlorococcus sp. MIT 0601].	21.96	624	379	20	3	572	5	574	6e-12	79.7
rs:WP_038052696	DNA topoisomerase I, partial [Thermomonas fusca].	24.09	469	301	14	103	538	80	526	6e-12	79.3
rs:WP_001948078	DNA topoisomerase [Helicobacter pylori].	23.34	467	307	12	99	537	77	520	6e-12	79.3
tr:A0A0E0NQ37_ORYRU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ORUFI03G04550.1};	21.28	733	441	31	3	653	13	691	6e-12	79.7
tr:F6QP60_MONDO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.44	468	291	17	188	619	156	587	6e-12	79.7
rs:WP_012829725	DNA topoisomerase I [Haliangium ochraceum].	22.62	663	396	21	3	616	139	733	6e-12	79.7
rs:WP_028832336	DNA topoisomerase I, partial [Proteobacteria bacterium JGI 0000113-E04].	24.17	451	301	11	81	521	1	420	6e-12	79.3
rs:WP_026631521	DNA topoisomerase I [Dyadobacter alkalitolerans].	22.98	531	339	18	3	520	5	478	6e-12	79.3
gpu:CP009530_2314	DNA topoisomerase I [Methanosarcina barkeri 227]	23.51	587	341	23	90	611	92	635	6e-12	79.3
rs:WP_002597513	DNA topoisomerase I [Clostridium colicanis].	23.32	669	402	25	2	629	4	602	6e-12	79.3
tr:G9YGB0_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.13	601	365	20	82	631	114	668	6e-12	79.3
rs:WP_011585715	DNA topoisomerase I [Cytophaga hutchinsonii].	23.01	539	335	15	3	520	5	484	6e-12	79.3
rs:WP_021288439	DNA topoisomerase I [Sulfurimonas sp. AST-10].	22.98	692	411	27	1	646	1	616	6e-12	79.3
rs:WP_012857987	DNA topoisomerase I [Sulfurospirillum deleyianum].	22.71	643	399	21	3	614	8	583	6e-12	79.3
rs:WP_041572492	DNA topoisomerase I, partial [Candidatus Azobacteroides pseudotrichonymphae].	22.68	538	354	13	3	530	5	490	6e-12	79.3
rs:WP_027188295	DNA topoisomerase I [Desulfovibrio cuneatus].	23.03	608	356	22	76	630	53	601	6e-12	79.3
tr:D6KHW4_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.93	580	353	23	95	629	98	628	6e-12	79.3
rs:WP_005095508	DNA topoisomerase I [Acinetobacter lwoffii].	24.53	375	228	11	187	541	212	551	6e-12	79.3
rs:WP_043633714	DNA topoisomerase I [Desulfovibrio sp. TomC].	24.39	652	380	29	76	669	53	649	6e-12	79.3
tr:A0A093R579_PHACA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.20	487	299	16	188	634	221	672	6e-12	79.7
rs:XP_004918127	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Xenopus (Silurana) tropicalis].	23.73	472	280	16	188	619	244	675	6e-12	79.7
rs:XP_011629125	PREDICTED: DNA topoisomerase 3-alpha [Amborella trichopoda].	22.39	670	430	26	3	623	8	636	6e-12	79.3
rs:WP_003607894	DNA topoisomerase I [Weissella confusa].	23.92	669	397	28	3	629	29	627	6e-12	79.3
rs:WP_029103165	DNA topoisomerase I [Moraxella caprae].	21.70	728	452	25	3	670	13	682	6e-12	79.3
rs:WP_004072698	DNA topoisomerase I [Desulfobacter postgatei].	23.19	595	387	19	74	630	51	613	6e-12	79.3
rs:XP_004012784	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Ovis aries].	22.91	502	315	17	171	634	222	689	6e-12	79.7
rs:WP_021677229	DNA topoisomerase I [Porphyromonas gingivalis].	24.35	538	324	19	3	520	4	478	7e-12	79.3
rs:WP_032016573	DNA topoisomerase I, partial [Acinetobacter baumannii].	24.81	387	219	12	273	629	27	371	7e-12	79.0
rs:WP_021716824	DNA topoisomerase [Phascolarctobacterium sp. CAG:266].	22.80	649	400	26	3	615	5	588	7e-12	79.3
tr:G4L412_TETHN	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:BAK95691.1};	26.52	230	153	5	463	680	59	284	7e-12	76.6
rs:XP_007425114	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Python bivittatus].	23.40	483	303	17	188	634	144	595	7e-12	79.3
rs:WP_031158108	DNA topoisomerase I [Streptosporangium roseum].	23.19	608	313	24	2	530	12	544	7e-12	79.3
rs:WP_010739369	DNA topoisomerase 1 [Enterococcus malodoratus].	23.42	585	371	23	90	635	68	614	7e-12	79.3
rs:WP_033489090	DNA topoisomerase I [Bifidobacterium pseudolongum].	21.96	624	386	18	2	571	6	582	7e-12	79.3
gpu:CP009967_4	DNA topoisomerase family protein [Bacillus cereus E33L]	30.43	207	127	6	470	660	1	206	7e-12	76.3
rs:WP_013455663	DNA topoisomerase I [Marivirga tractuosa].	24.93	377	241	10	157	520	132	479	7e-12	79.3
rs:WP_032568790	DNA topoisomerase I [Bacteroides fragilis].	24.44	626	371	29	3	604	5	552	7e-12	79.3
rs:WP_021812978	DNA topoisomerase I [Psychrobacter aquaticus].	24.33	637	402	26	77	673	100	696	7e-12	79.3
tr:I7BKR0_MYCHA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00003390}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.35	575	343	19	90	614	73	605	7e-12	79.3
rs:WP_036476290	DNA topoisomerase I [Nesterenkonia sp. AN1].	22.67	591	347	21	2	530	12	554	7e-12	79.3
tr:A0A096SY28_MAIZE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.10	387	236	17	39	391	275	645	7e-12	79.3
rs:WP_030886590	DNA topoisomerase I [Streptomyces sp. NRRL F-5053].	23.79	597	328	23	2	530	13	550	7e-12	79.3
rs:WP_030260198	DNA topoisomerase I [Streptomyces violens].	23.09	589	340	21	2	530	14	549	7e-12	79.3
rs:WP_028972477	hypothetical protein [Spirochaeta cellobiosiphila].	22.41	665	423	21	3	629	10	619	7e-12	79.3
rs:WP_037194447	DNA topoisomerase I [Rhizobium sp. OK494].	21.79	661	410	25	38	630	16	637	7e-12	79.3
rs:WP_039615782	DNA topoisomerase I [Rhodobacteraceae bacterium PD-2].	22.30	610	332	22	1	534	1	544	7e-12	79.3
rs:WP_015361490	DNA topoisomerase [Nonlabens dokdonensis].	24.82	548	308	19	3	521	5	477	7e-12	79.3
tr:S6EZ85_ZYGB2	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.99	670	382	27	3	584	4	627	7e-12	79.0
rs:WP_037866264	DNA topoisomerase I [Streptomyces sp. NRRL S-1868].	23.79	597	328	23	2	530	13	550	7e-12	79.3
tr:J9FUN1_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EJW98213.1};	23.29	554	336	20	3	531	5	494	7e-12	79.3
rs:WP_027846908	DNA topoisomerase I [Mastigocoleus testarum].	24.51	559	330	17	100	603	82	603	7e-12	79.3
rs:WP_009756043	DNA topoisomerase I [Nitratireductor indicus].	21.47	708	404	26	1	630	1	634	7e-12	79.3
rs:WP_018233248	DNA topoisomerase I [Thioalkalivibrio thiocyanodenitrificans].	24.59	484	299	16	88	534	66	520	7e-12	79.3
rs:WP_044303446	DNA topoisomerase I [Rhodopirellula sallentina].	23.20	582	338	16	3	530	27	553	7e-12	79.3
rs:WP_041592025	DNA topoisomerase, partial [Tetragenococcus halophilus].	26.52	230	153	5	463	680	54	279	7e-12	76.6
rs:XP_012551245	PREDICTED: DNA topoisomerase 3-alpha [Bombyx mori].	25.00	556	325	23	46	560	89	593	7e-12	79.3
rs:WP_009779100	DNA topoisomerase I [Leeuwenhoekiella blandensis].	24.20	533	330	16	3	521	5	477	7e-12	79.3
rs:WP_025899806	DNA topoisomerase I [Sneathiella glossodoripedis].	22.76	602	375	23	1	565	1	549	7e-12	79.3
rs:WP_008930828	DNA topoisomerase I [Ectothiorhodospira sp. PHS-1].	21.95	574	348	20	3	534	5	520	7e-12	79.3
tr:X2H807_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.80	198	113	6	188	365	21	212	7e-12	75.9
rs:WP_011256239	DNA topoisomerase I [Wolbachia endosymbiont of Brugia malayi].	24.52	571	336	23	1	534	1	513	7e-12	79.3
rs:XP_007864007	prokaryotic type I DNA topoisomerase [Gloeophyllum trabeum ATCC 11539].	23.14	579	366	20	3	537	4	547	7e-12	79.0
rs:XP_956391	DNA topoisomerase 3-beta [Neurospora crassa OR74A].	22.42	562	351	20	3	521	33	552	7e-12	79.0
rs:WP_040849999	DNA topoisomerase I [Thiovulum sp. ES].	23.62	580	358	21	3	554	4	526	7e-12	79.0
rs:WP_038125361	DNA topoisomerase I [Veillonella sp. 3_1_44].	22.93	580	353	23	95	629	142	672	7e-12	79.3
rs:XP_004985595	PREDICTED: DNA topoisomerase 3-alpha [Setaria italica].	22.46	641	389	25	3	585	13	603	7e-12	79.3
rs:WP_018033543	hypothetical protein, partial [crenarchaeote SCGC AAA261-L14].	26.54	260	182	5	78	336	329	580	7e-12	79.0
rs:WP_030543868	DNA topoisomerase I [Streptomyces albus].	22.84	591	340	21	2	530	13	549	7e-12	79.3
rs:WP_012794913	reverse gyrase [Methanocaldococcus fervens].	24.90	518	304	18	82	576	663	1118	7e-12	79.3
rs:WP_022956231	topoisomerase I [Perlucidibaca piscinae].	23.62	597	367	23	74	629	90	638	7e-12	79.3
rs:WP_009347727	DNA topoisomerase I [Alloprevotella rava].	23.35	544	331	21	3	526	7	484	7e-12	79.3
rs:WP_029391222	DNA topoisomerase I [Streptomyces xiaopingdaonensis].	22.91	598	331	23	2	530	13	549	7e-12	79.3
tr:F7C5J9_XENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.30	455	301	15	3	426	5	442	7e-12	78.6
rs:WP_017192797	hypothetical protein [Italian clover phyllody phytoplasma].	23.31	652	406	23	70	687	53	644	7e-12	79.0
rs:WP_018142403	hypothetical protein [Metascardovia criceti].	24.36	628	367	24	2	571	6	583	7e-12	79.3
tr:G6DDL0_DANPL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.58	434	256	16	179	589	199	588	7e-12	79.0
rs:WP_041350251	DNA topoisomerase I [Clostridium botulinum].	25.19	659	373	28	3	616	5	588	7e-12	79.0
tr:A0A023CUK7_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	22.18	478	314	16	187	635	8	456	7e-12	78.6
rs:XP_008073442	hypothetical protein VCUG_00424 [Vavraia culicis subsp. floridensis].	22.42	611	406	20	1	565	1	589	7e-12	79.3
tr:W6TE90_HOLOB	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.30	618	389	23	64	629	44	628	8e-12	79.3
rs:XP_002527391	prokaryotic DNA topoisomerase, putative, partial [Ricinus communis].	21.46	643	396	25	3	585	5	598	8e-12	79.3
gpu:CP008746_1387	DNA topoisomerase I TopA2 [Methanosarcina barkeri CM1]	23.51	587	341	23	90	611	92	635	8e-12	79.3
rs:XP_010159682	PREDICTED: DNA topoisomerase 3-alpha, partial [Eurypyga helias].	23.59	479	307	17	188	634	241	692	8e-12	79.3
rs:WP_040535946	DNA topoisomerase I [Gordonia namibiensis].	24.87	587	333	23	2	530	16	552	8e-12	79.3
tr:W4YMN5_STRPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:SPU_017059-tr};	23.77	387	253	13	188	560	76	434	8e-12	79.0
rs:WP_040458502	hypothetical protein, partial [Holospora obtusa].	23.23	607	384	22	75	629	52	628	8e-12	79.3
rs:WP_003146872	DNA topoisomerase I [Gemella haemolysans].	23.83	575	336	21	103	629	81	601	8e-12	79.0
rs:XP_008189109	PREDICTED: DNA topoisomerase 3-alpha-like, partial [Acyrthosiphon pisum].	24.73	372	217	11	187	533	74	407	8e-12	78.2
rs:XP_009988506	PREDICTED: DNA topoisomerase 3-alpha, partial [Tauraco erythrolophus].	24.73	461	283	18	188	616	179	607	8e-12	79.3
tr:W1NMN0_AMBTC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.39	670	430	26	3	623	84	712	8e-12	79.3
rs:XP_011357356	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Pteropus vampyrus].	22.34	488	302	15	188	634	239	690	8e-12	79.3
tr:A0A0E0G6J5_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA02G17860.1};	22.41	647	387	27	39	612	308	912	8e-12	79.3
rs:XP_009508111	PREDICTED: DNA topoisomerase 3-alpha [Phalacrocorax carbo].	23.20	487	299	16	188	634	241	692	8e-12	79.3
tr:F7A1S4_XENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.35	471	283	15	188	619	243	674	8e-12	79.3
rs:WP_038464132	DNA topoisomerase I [Candidatus Paracaedibacter acanthamoebae].	21.80	679	426	27	3	629	4	629	8e-12	79.0
rs:WP_028901497	DNA topoisomerase I [Prevotella corporis].	22.50	600	379	20	3	580	5	540	8e-12	79.0
tr:C5GXA3_AJEDR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.56	640	410	20	3	586	6	609	8e-12	79.0
rs:WP_013792006	topoisomerase I [Pseudomonas fulva].	23.64	478	301	15	186	633	194	637	8e-12	79.3
tr:U6MZY6_9EIME	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.74	396	250	14	188	564	49	411	8e-12	79.0
rs:XP_008667757	PREDICTED: hypothetical protein isoform X2 [Zea mays].	22.31	641	390	25	3	585	12	602	8e-12	79.3
rs:XP_001510142	PREDICTED: DNA topoisomerase 3-alpha [Ornithorhynchus anatinus].	23.66	465	289	16	188	619	234	665	8e-12	79.3
rs:WP_036859601	hypothetical protein [Prevotella disiens].	35.21	142	90	2	171	311	1	141	8e-12	74.7
tr:D6KN24_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.57	567	371	22	95	629	98	628	8e-12	79.0
rs:WP_025801906	DNA topoisomerase I [Campylobacter sp. CIT045].	23.29	657	377	24	3	614	4	578	8e-12	79.0
rs:WP_011280924	topoisomerase I [Psychrobacter arcticus].	23.96	601	362	24	77	629	104	657	8e-12	79.3
rs:WP_032485350	DNA topoisomerase III, partial [Yersinia pestis].	41.94	93	54	0	489	581	1	93	8e-12	74.3
rs:WP_019204639	topoisomerase I, partial [Acinetobacter baumannii].	24.81	387	219	12	273	629	20	364	8e-12	78.6
tr:Q2PY64_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.50	532	336	18	3	521	5	478	8e-12	79.0
rs:WP_039964959	DNA topoisomerase I [Veillonella sp. 6_1_27].	22.50	569	369	23	95	629	142	672	8e-12	79.0
rs:WP_041654938	DNA topoisomerase I [Arcobacter sp. L].	24.87	563	337	23	3	533	4	512	8e-12	79.0
rs:WP_013989151	DNA topoisomerase I [Weissella koreensis].	24.91	582	351	27	90	629	85	622	8e-12	79.0
tr:A0A0E0CKE1_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OMERI02G16280.12};	22.82	631	372	28	39	612	310	882	8e-12	79.3
rs:WP_018966719	DNA topoisomerase I [Prevotella loescheii].	22.90	607	363	19	3	580	5	535	8e-12	79.0
rs:WP_026644748	DNA topoisomerase I [Bifidobacterium sp. AGR2158].	21.48	647	395	19	2	580	6	607	8e-12	79.3
rs:XP_001483632	hypothetical protein PGUG_04361 [Meyerozyma guilliermondii ATCC 6260].	22.77	606	385	22	3	560	4	574	8e-12	78.6
rs:WP_045725701	DNA topoisomerase I [Clostridium baratii].	22.12	669	410	23	2	629	4	602	8e-12	79.0
tr:V9KK95_CALMI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	21.82	472	289	17	188	619	208	639	8e-12	79.0
tr:Q5CBQ4_THENE	RecName: Full=Reverse gyrase {ECO:0000256|HAMAP-Rule:MF_01125, ECO:0000256|RuleBase:RU004026};	22.34	479	273	14	81	533	659	1064	8e-12	79.3
rs:WP_010729566	hypothetical protein, partial [Enterococcus faecium].	32.26	124	80	3	3	123	5	127	8e-12	73.9
tr:U4TCR0_PISSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.44	487	294	20	88	533	39	492	8e-12	79.0
rs:WP_002812072	DNA topoisomerase I [Nitrosococcus oceani].	22.88	577	348	23	3	534	5	529	8e-12	79.0
rs:WP_029815476	DNA topoisomerase III, partial [Yersinia pestis].	42.39	92	53	0	490	581	1	92	8e-12	74.3
tr:A0A0D3F545_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OBART02G16520.1};	22.46	619	371	25	64	610	272	853	8e-12	79.3
rs:XP_008650522	PREDICTED: uncharacterized protein LOC103631377 [Zea mays].	26.32	361	222	15	64	391	352	701	8e-12	79.3
rs:WP_031449654	DNA topoisomerase I [Desulfobacula sp. TS].	24.69	571	350	24	82	614	59	587	8e-12	79.0
rs:WP_015919009	reverse gyrase [Thermotoga neapolitana].	22.74	475	276	14	81	533	640	1045	8e-12	79.3
rs:XP_010907414	PREDICTED: DNA topoisomerase 3-alpha [Elaeis guineensis].	21.64	633	406	24	3	585	13	605	8e-12	79.0
rs:WP_014217896	DNA topoisomerase I [Niastella koreensis].	23.83	596	374	18	3	580	5	538	8e-12	79.0
rs:WP_042660073	hypothetical protein, partial [Aigarchaeota archaeon JGI 0000106-J15].	24.53	632	364	24	1	581	559	1128	8e-12	79.3
tr:A0A0B1U4C5_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.39	652	380	29	76	669	64	660	9e-12	79.0
rs:WP_020185324	hypothetical protein [Methylopila sp. 73B].	23.20	638	395	25	55	629	28	633	9e-12	79.0
rs:WP_032136609	DNA topoisomerase I [Kingella sp. Sch538].	21.59	681	421	23	70	679	37	675	9e-12	79.0
rs:WP_006845568	DNA topoisomerase I [Weissella koreensis].	24.91	582	351	27	90	629	85	622	9e-12	79.0
rs:WP_008270706	DNA topoisomerase I [Flavobacteriales bacterium ALC-1].	27.34	384	232	11	154	521	128	480	9e-12	79.0
tr:A0A0B0EM62_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.79	601	360	22	3	578	5	532	9e-12	79.0
rs:XP_006908497	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Pteropus alecto].	22.34	488	302	15	188	634	239	690	9e-12	79.3
rs:WP_014554820	DNA topoisomerase I [Gardnerella vaginalis].	23.86	637	353	24	2	571	6	577	9e-12	79.0
rs:XP_662159	hypothetical protein AN4555.2 [Aspergillus nidulans FGSC A4].	22.99	635	380	24	3	573	7	596	9e-12	78.6
tr:Q5CBC0_9THEM	RecName: Full=Reverse gyrase {ECO:0000256|HAMAP-Rule:MF_01125, ECO:0000256|RuleBase:RU004026};	24.26	474	270	15	81	533	643	1048	9e-12	79.3
rs:WP_004754292	DNA topoisomerase I [Acinetobacter sp. ANC 3789].	21.59	477	300	12	187	629	212	648	9e-12	79.0
rs:WP_030035662	DNA topoisomerase I [Clostridium botulinum].	24.89	663	370	29	3	616	5	588	9e-12	79.0
rs:WP_036373819	DNA topoisomerase I [Mitsuokella jalaludinii].	22.91	563	368	18	90	616	97	629	9e-12	79.0
tr:A0A0E0CKE5_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OMERI02G16280.4};	22.89	629	370	28	39	610	310	880	9e-12	79.3
rs:WP_040054253	DNA topoisomerase I [Candidatus Atelocyanobacterium thalassa].	22.70	630	373	23	3	574	4	577	9e-12	79.0
rs:XP_007338605	prokaryotic type I DNA topoisomerase [Auricularia delicata TFB-10046 SS5].	21.04	656	418	21	3	608	4	609	9e-12	78.6
gp:FR773526_2425	DNA topoisomerase I [Clostridium botulinum H04402 065]	25.49	663	366	30	3	616	9	592	9e-12	79.0
rs:WP_039432234	DNA topoisomerase I [Porphyromonas gulae].	23.54	531	336	15	3	520	4	477	9e-12	79.0
rs:WP_036253930	MULTISPECIES: DNA topoisomerase I, partial [Mesorhizobium].	22.40	692	416	29	1	630	1	633	9e-12	79.0
tr:A0A093D0I4_TAUER	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.38	484	297	19	188	634	180	631	9e-12	79.0
rs:WP_034017814	hypothetical protein [Pseudomonas aeruginosa].	21.97	619	391	20	31	616	17	576	9e-12	78.6
rs:WP_009628373	DNA topoisomerase I [Pseudanabaena biceps].	20.90	665	413	23	2	614	3	606	9e-12	79.0
rs:WP_034576267	DNA topoisomerase I [Cardinium endosymbiont of Bemisia tabaci].	24.23	520	330	14	77	578	54	527	9e-12	79.0
tr:A0A0D2PB21_9AGAR	SubName: Full=Unplaced genomic scaffold scaffold_85, whole genome shotgun sequence {ECO:0000313|EMBL:KJA17535.1};	20.79	630	413	20	3	586	4	593	9e-12	79.0
rs:XP_001609564	DNA topoisomerase [Babesia bovis T2Bo].	22.14	637	397	23	3	574	7	609	9e-12	79.0
rs:WP_015652572	hypothetical protein [uncultured Sulfuricurvum sp. RIFRC-1].	21.92	657	395	23	1	616	1	580	9e-12	79.0
rs:XP_008120111	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Anolis carolinensis].	23.14	484	303	18	188	634	243	694	9e-12	79.0
rs:WP_046720326	DNA topoisomerase III, partial [Pseudomonas syringae].	35.42	144	80	4	190	321	1	143	9e-12	75.1
rs:XP_003072754	DNA topoisomerase III [Encephalitozoon intestinalis ATCC 50506].	22.52	604	388	22	3	573	4	560	9e-12	79.0
rs:WP_013637986	reverse gyrase [Desulfurobacterium thermolithotrophum].	24.95	505	292	16	103	579	733	1178	9e-12	79.3
rs:WP_031505016	hypothetical protein [Pseudothermotoga hypogea].	23.00	526	322	17	82	586	647	1110	9e-12	79.0
rs:WP_044561089	hypothetical protein [Azospirillum sp. B4].	21.38	580	372	21	37	546	48	613	9e-12	79.0
rs:WP_016459514	DNA topoisomerase I [Acidaminococcus sp. HPA0509].	21.28	639	424	18	3	616	4	588	9e-12	79.0
rs:WP_011503433	DNA topoisomerase I [Rhodopseudomonas palustris].	22.50	689	419	30	1	630	1	633	9e-12	79.0
rs:WP_041844072	reverse gyrase [Thermotoga sp. RQ7].	22.74	475	276	14	81	533	640	1045	9e-12	79.0
tr:I7BY88_PSEPT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AFO49117.1};	31.11	135	90	1	450	581	14	148	9e-12	75.1
tr:T2SIG3_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	23.34	467	307	12	99	537	80	523	9e-12	78.6
rs:WP_020759764	DNA topoisomerase I [Gardnerella vaginalis].	23.70	637	354	24	2	571	6	577	9e-12	79.0
rs:WP_015132934	DNA topoisomerase I [Leptolyngbya sp. PCC 7376].	23.36	578	340	17	3	530	4	528	1e-11	79.0
tr:A0A0E0IGT0_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA09G02300.1};	21.04	732	449	30	3	653	65	748	1e-11	79.0
rs:WP_027048371	DNA topoisomerase I [Mesoplasma syrphidae].	24.51	563	347	22	3	533	5	521	1e-11	78.6
rs:WP_002664442	DNA topoisomerase I, partial [Streptococcus pneumoniae].	26.38	326	210	10	87	392	75	390	1e-11	77.8
rs:WP_045246069	DNA topoisomerase I [Microbacterium ginsengisoli].	23.21	560	344	19	32	538	6	532	1e-11	79.0
rs:WP_032126693	DNA topoisomerase I [Piscirickettsia salmonis].	24.44	487	294	20	88	533	66	519	1e-11	79.0
tr:T1L4W6_TETUR	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:tetur41g00370.1};	23.14	605	368	25	46	606	96	647	1e-11	78.6
rs:WP_045792501	DNA topoisomerase I [Acinetobacter brisouii].	22.64	477	295	14	187	629	212	648	1e-11	79.0
gp:FJ666348_34	TraB [Synthetic plasmid pMOL98]	22.61	575	367	21	90	631	74	603	1e-11	79.0
rs:WP_009014722	MULTISPECIES: DNA topoisomerase I [Acidaminococcus].	21.28	639	424	18	3	616	4	588	1e-11	79.0
rs:WP_027341883	DNA topoisomerase I [Hamadaea tsunoensis].	20.71	729	385	26	2	642	8	631	1e-11	79.0
rs:WP_033992850	hypothetical protein, partial [Pseudomonas aeruginosa].	22.73	484	295	16	163	619	138	569	1e-11	78.6
rs:WP_003829064	DNA topoisomerase I [Citrobacter freundii].	22.81	583	373	22	90	641	65	601	1e-11	78.6
rs:WP_044147783	DNA topoisomerase I [Ehrlichia chaffeensis].	23.90	749	441	31	1	684	1	685	1e-11	79.0
tr:A0A094HBG3_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFZ12247.1};	21.88	521	349	17	35	533	74	558	1e-11	78.6
tr:A0A094FE55_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY89129.1};	21.88	521	349	17	35	533	74	558	1e-11	78.6
tr:G1SQY7_RABIT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.30	485	301	17	188	634	240	691	1e-11	79.0
rs:WP_034554683	DNA topoisomerase I [Helicobacter apodemus].	21.81	642	406	19	3	614	4	579	1e-11	78.6
tr:L9LCG8_TUPCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.65	446	268	12	188	585	261	677	1e-11	79.0
tr:A0A010YGE9_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.41	665	346	30	1	571	26	614	1e-11	79.0
rs:WP_031250841	DNA topoisomerase I [Helicobacter pylori].	23.34	467	307	12	99	537	77	520	1e-11	78.6
rs:XP_008667760	PREDICTED: hypothetical protein isoform X3 [Zea mays].	22.41	638	368	24	3	585	12	577	1e-11	79.0
rs:WP_010441666	DNA topoisomerase I [Ruegeria conchae].	26.67	330	197	11	1	314	1	301	1e-11	79.0
rs:WP_039171001	DNA topoisomerase I [Bifidobacterium pseudolongum].	21.79	624	387	19	2	571	6	582	1e-11	79.0
tr:R2B473_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOF89207.1};	26.52	230	153	5	463	680	11	236	1e-11	75.5
rs:XP_002289424	topoisomerase, partial [Thalassiosira pseudonana CCMP1335].	20.43	553	378	15	46	564	77	601	1e-11	78.6
rs:WP_007664856	hypothetical protein [Bacteroides intestinalis].	35.77	123	62	4	4	115	7	123	1e-11	73.6
rs:XP_006901251	PREDICTED: DNA topoisomerase 3-alpha [Elephantulus edwardii].	24.03	491	290	20	188	634	214	665	1e-11	79.0
rs:XP_003228350	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Anolis carolinensis].	23.14	484	303	18	188	634	212	663	1e-11	79.0
rs:XP_008120112	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Anolis carolinensis].	23.14	484	303	18	188	634	223	674	1e-11	79.0
tr:I7KUW7_9CLOT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.81	513	331	13	90	572	67	544	1e-11	78.2
tr:A0A0A7GC78_9EURY	RecName: Full=Reverse gyrase {ECO:0000256|HAMAP-Rule:MF_01125, ECO:0000256|RuleBase:RU004026};	25.14	533	284	26	81	587	624	1067	1e-11	79.0
rs:WP_016874429	DNA topoisomerase I [Chlorogloeopsis fritschii].	23.92	577	358	21	79	610	59	599	1e-11	78.6
rs:WP_035400416	DNA topoisomerase I [Faecalitalea cylindroides].	22.96	649	389	22	3	611	5	582	1e-11	78.6
tr:K2E740_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.97	653	405	20	1	614	1	594	1e-11	78.6
tr:G7JC55_MEDTR	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	23.11	636	392	27	3	585	9	600	1e-11	79.0
rs:WP_007545468	reverse gyrase [Sulfurihydrogenibium yellowstonense].	22.62	557	338	18	3	533	599	1088	1e-11	79.0
rs:WP_014032176	DNA topoisomerase I [Muricauda ruestringensis].	24.95	465	295	13	157	604	132	559	1e-11	78.6
rs:WP_006460213	DNA topoisomerase I [Thioalkalimicrobium aerophilum].	22.35	613	393	21	3	596	4	552	1e-11	78.6
tr:W1DTU0_KLEPN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CDL12871.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDL12871.1};	38.54	96	59	0	486	581	8	103	1e-11	74.3
rs:WP_028089487	DNA topoisomerase I [Dolichospermum circinale].	22.44	615	391	20	3	574	4	575	1e-11	78.6
rs:WP_015202460	DNA topoisomerase I [Crinalium epipsammum].	23.19	595	347	22	90	626	71	613	1e-11	78.6
rs:XP_005807446	PREDICTED: DNA topoisomerase 3-beta-1-like [Xiphophorus maculatus].	21.04	613	391	19	3	564	5	575	1e-11	78.6
rs:WP_031586825	DNA topoisomerase I [Selenomonas bovis].	23.40	564	364	21	90	616	102	634	1e-11	78.6
tr:A0A0E0NET5_ORYRU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ORUFI02G17070.1};	22.41	647	387	27	39	612	261	865	1e-11	79.0
rs:WP_012037613	DNA topoisomerase I [Clavibacter michiganensis].	23.00	587	338	21	2	528	6	538	1e-11	79.0
rs:XP_012489371	PREDICTED: DNA topoisomerase 3-alpha isoform X4 [Gossypium raimondii].	22.80	636	394	24	3	585	8	599	1e-11	78.6
tr:A0A0E0G6J6_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA02G17860.2};	22.59	633	375	26	39	610	308	886	1e-11	79.0
rs:WP_041926692	DNA topoisomerase I [Clostridium botulinum].	25.49	663	366	30	3	616	5	588	1e-11	78.6
rs:WP_019943304	DNA topoisomerase I [Dyadobacter beijingensis].	24.24	458	299	12	77	520	54	477	1e-11	78.6
rs:WP_035903648	DNA topoisomerase I [Knoellia subterranea].	23.50	583	343	19	2	530	9	542	1e-11	78.6
tr:K1U4K1_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC77123.1};	37.40	123	70	2	465	586	7	123	1e-11	74.3
gp:Z14112_2	DNA topoisomerase I [Bacillus firmus]	29.10	244	133	10	283	507	3	225	1e-11	75.5
rs:WP_026809853	DNA topoisomerase I [Arenibacter latericius].	24.44	532	332	16	3	521	5	479	1e-11	78.6
rs:WP_038608548	DNA topoisomerase I [Bacteroides dorei].	23.93	560	359	17	77	617	54	565	1e-11	78.6
rs:WP_040248414	DNA topoisomerase I [Psychroserpens mesophilus].	24.87	378	246	10	154	521	128	477	1e-11	78.6
tr:X1WUB7_ACYPI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.66	373	218	11	186	533	171	505	1e-11	78.2
rs:WP_014857204	DNA topoisomerase I [Melioribacter roseus].	23.99	642	382	24	55	629	29	631	1e-11	78.6
rs:WP_040636070	DNA topoisomerase I [Mitsuokella multacida].	23.83	579	357	20	83	616	93	632	1e-11	78.6
rs:WP_029247485	DNA topoisomerase I [Schlesneria paludicola].	22.96	614	366	19	2	560	3	564	1e-11	78.6
rs:WP_037980021	DNA topoisomerase I [Streptomyces sp. TAA040].	23.46	601	325	22	2	530	13	550	1e-11	78.6
rs:WP_001937348	DNA topoisomerase [Helicobacter pylori].	23.34	467	307	12	99	537	9	452	1e-11	78.2
tr:V9KDD5_CALMI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.61	472	290	17	188	619	229	660	1e-11	78.6
rs:WP_046825087	DNA topoisomerase I [Tannerella forsythia].	23.80	542	326	18	2	520	4	481	1e-11	78.6
rs:XP_012489370	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Gossypium raimondii].	22.80	636	394	24	3	585	8	599	1e-11	78.6
rs:WP_004026228	DNA topoisomerase I [Ureaplasma urealyticum].	24.11	593	350	27	90	629	71	616	1e-11	78.2
rs:WP_041464266	DNA topoisomerase I [Clavibacter michiganensis].	22.83	587	339	20	2	528	6	538	1e-11	78.6
rs:WP_031325380	DNA topoisomerase III, partial [Pseudomonas taiwanensis].	32.48	117	79	0	465	581	28	144	1e-11	74.7
tr:U2PF89_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.96	649	389	22	3	611	14	591	1e-11	78.6
rs:WP_038235709	DNA topoisomerase I [Zobellia uliginosa].	25.27	455	303	10	76	521	53	479	1e-11	78.6
rs:XP_008248583	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha [Oryctolagus cuniculus].	22.66	481	309	16	188	634	240	691	1e-11	78.6
rs:XP_002995407	hypothetical protein NCER_101713 [Nosema ceranae BRL01].	23.85	608	386	21	3	579	4	565	1e-11	78.6
rs:WP_014733806	reverse gyrase [Pyrococcus sp. ST04].	24.89	450	242	16	162	580	826	1210	1e-11	79.0
rs:WP_014414404	DNA topoisomerase I [Rhodospirillum photometricum].	21.82	724	435	29	1	656	1	661	1e-11	78.6
rs:XP_006382211	hypothetical protein POPTR_0006s29400g [Populus trichocarpa].	22.57	638	397	27	32	610	334	933	1e-11	78.6
rs:WP_044106603	DNA topoisomerase I [cyanobacterium endosymbiont of Epithemia turgida].	23.25	585	333	18	3	530	4	529	1e-11	78.6
tr:D5DPQ9_BACMQ	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ADE68980.1};	31.78	129	87	1	446	573	37	165	1e-11	75.9
rs:WP_013231643	DNA topoisomerase I [Leuconostoc gelidum].	21.71	539	364	14	103	616	103	608	1e-11	78.2
rs:WP_014970695	DNA topoisomerase I [Exiguobacterium antarcticum].	22.37	666	416	26	3	630	5	607	1e-11	78.2
gpu:CP009508_2633	DNA topoisomerase I [Methanosarcina siciliae C2J]	22.80	636	399	26	21	611	27	615	1e-11	78.6
rs:WP_034991900	DNA topoisomerase I [Beijerinckia mobilis].	23.76	686	411	27	1	629	1	631	1e-11	78.6
rs:WP_032115003	DNA topoisomerase I [Arsenophonus endosymbiont of Nilaparvata lugens].	23.67	490	286	17	187	633	189	633	1e-11	78.6
rs:WP_044418591	DNA topoisomerase I [Rhodopseudomonas palustris].	23.52	693	405	32	1	629	1	632	1e-11	78.6
rs:XP_010229157	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Brachypodium distachyon].	23.68	418	266	13	188	585	45	429	1e-11	78.6
rs:XP_012489368	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Gossypium raimondii].	22.80	636	394	24	3	585	8	599	1e-11	78.6
rs:XP_005949420	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X2 [Haplochromis burtoni].	22.02	563	363	18	38	564	42	564	1e-11	78.2
rs:WP_011452790	DNA topoisomerase I [Ehrlichia chaffeensis].	23.77	749	442	31	1	684	1	685	1e-11	78.6
rs:XP_012489369	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Gossypium raimondii].	22.80	636	394	24	3	585	8	599	1e-11	78.6
tr:C9KMX8_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.83	579	357	20	83	616	86	625	1e-11	78.2
rs:WP_039808911	DNA topoisomerase I [Nocardia otitidiscaviarum].	23.28	597	333	22	2	530	24	563	1e-11	78.6
rs:WP_009538494	DNA topoisomerase I [Caenispirillum salinarum].	21.32	699	413	26	1	630	1	631	1e-11	78.6
rs:WP_036881443	DNA topoisomerase I [Porphyromonas sp. COT-239 OH1446].	22.06	535	346	15	3	521	5	484	1e-11	78.2
tr:A0A0B2UFU6_9MICR	SubName: Full=Topoisomerase IA {ECO:0000313|EMBL:KHN69956.1};	22.43	575	375	19	46	596	52	579	1e-11	78.2
tr:F4BRM5_CARS1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	21.25	480	320	15	187	635	7	459	1e-11	77.8
rs:XP_002629150	DNA topoisomerase III [Blastomyces dermatitidis SLH14081].	21.77	643	405	21	3	586	6	609	1e-11	78.2
rs:WP_008856759	DNA topoisomerase I [Lactobacillus kisonensis].	22.04	558	368	18	103	629	100	621	1e-11	78.2
rs:NP_194849	DNA topoisomerase, type IA, core [Arabidopsis thaliana].	23.57	543	331	23	32	527	490	995	1e-11	78.6
rs:WP_001923555	DNA topoisomerase [Helicobacter pylori].	24.26	470	300	15	99	537	77	521	1e-11	78.2
rs:XP_001027980	DNA topoisomerase I [Tetrahymena thermophila SB210].	23.34	634	381	26	3	578	208	794	1e-11	78.6
rs:XP_011357358	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Pteropus vampyrus].	22.97	492	294	16	188	634	72	523	1e-11	78.2
rs:XP_006908498	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Pteropus alecto].	22.97	492	294	16	188	634	72	523	1e-11	78.2
rs:WP_034047566	DNA topoisomerase I [Pseudomonas aeruginosa].	22.75	589	365	19	80	631	54	589	1e-11	78.2
rs:WP_008193954	MULTISPECIES: reverse gyrase [Thermotoga].	23.16	475	274	16	81	533	644	1049	1e-11	78.6
tr:G7E0M5_MIXOS	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:GAA96385.1};	22.68	635	378	26	3	577	5	586	1e-11	78.6
rs:WP_019836908	topoisomerase I [Acinetobacter sp. MDS7A].	23.32	476	293	16	187	629	211	647	1e-11	78.6
rs:WP_035748239	DNA topoisomerase I, partial [Flavobacterium sp. URHB0058].	30.10	206	130	8	475	676	2	197	1e-11	74.7
tr:E2ZN56_9FIRM	SubName: Full=Topoisomerase DNA-binding C4 zinc finger domain protein {ECO:0000313|EMBL:EFQ05397.1};	27.71	231	140	6	456	673	55	271	1e-11	75.5
rs:WP_012560269	DNA topoisomerase I [Ureaplasma urealyticum].	24.11	593	350	27	90	629	71	616	1e-11	78.2
rs:WP_045807821	DNA topoisomerase I [Lactobacillus spicheri].	23.52	591	366	25	88	635	78	625	1e-11	78.2
sp:RGYR_THEMA	RecName: Full=Reverse gyrase {ECO:0000255|HAMAP-Rule:MF_01125}; Includes: RecName: Full=Helicase {ECO:0000255|HAMAP-Rule:MF_01125}; EC=3.6.4.12 {ECO:0000255|HAMAP-Rule:MF_01125}; Includes: RecName: Full=Topoisomerase {ECO:0000255|HAMAP-Rule:MF_01125}; EC=5.99.1.3 {ECO:0000255|HAMAP-Rule:MF_01125};	23.16	475	274	16	81	533	644	1049	1e-11	78.6
rs:WP_043884230	DNA topoisomerase I, partial [Caldanaerobacter subterraneus].	24.62	463	278	20	90	518	67	492	1e-11	77.4
rs:WP_006275002	DNA topoisomerase I [Asticcacaulis biprosthecium].	20.78	688	425	22	1	629	1	627	1e-11	78.2
rs:WP_024078549	DNA topoisomerase I [Magnetospirillum gryphiswaldense].	22.22	693	419	27	1	630	1	636	1e-11	78.2
rs:XP_010447600	PREDICTED: uncharacterized protein LOC104730175 isoform X3 [Camelina sativa].	23.72	548	342	23	32	536	459	973	1e-11	78.6
rs:XP_001827899	DNA topoisomerase III [Enterocytozoon bieneusi H348].	22.40	634	426	20	5	606	6	605	1e-11	78.2
rs:WP_004976132	DNA topoisomerase I [Acinetobacter towneri].	23.79	475	292	15	187	629	211	647	1e-11	78.2
rs:WP_025479035	hypothetical protein [Enterococcus faecium].	33.57	140	86	2	265	400	3	139	1e-11	73.9
tr:R0MEX3_NOSB1	SubName: Full=DNA topoisomerase 3-alpha {ECO:0000313|EMBL:EOB11308.1};	22.86	560	356	19	46	577	8	519	1e-11	78.2
rs:WP_044954271	DNA topoisomerase III, partial [Faecalibacterium prausnitzii].	27.71	231	140	6	456	673	52	268	1e-11	75.5
tr:A0A022PYK0_ERYGU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.77	648	378	29	3	586	12	607	1e-11	78.2
rs:WP_043599342	DNA topoisomerase I [Nocardia otitidiscaviarum].	23.28	597	333	22	2	530	24	563	1e-11	78.6
rs:XP_005949421	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X3 [Haplochromis burtoni].	22.34	555	355	18	46	564	6	520	1e-11	77.8
rs:WP_021775997	DNA topoisomerase I [Jonquetella sp. BV3C21].	21.53	576	360	17	88	615	179	710	1e-11	78.2
rs:XP_011357357	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Pteropus vampyrus].	22.97	492	294	16	188	634	139	590	1e-11	78.2
rs:WP_031431468	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	29.26	188	118	5	210	382	3	190	1e-11	74.3
rs:WP_022855234	topoisomerase [Thermodesulfobacterium thermophilum].	25.36	481	268	15	82	536	699	1114	1e-11	78.6
rs:WP_033874334	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	29.61	152	92	2	467	614	32	172	1e-11	74.3
rs:WP_013480650	DNA topoisomerase I [Asticcacaulis excentricus].	21.23	683	427	23	1	629	1	626	2e-11	78.2
rs:XP_002772824	DNA topoisomerase 3-beta-1, putative [Perkinsus marinus ATCC 50983].	22.50	520	351	14	3	487	6	508	2e-11	78.2
rs:WP_010524349	DNA topoisomerase I [Nesterenkonia sp. F].	23.38	586	347	21	2	530	10	550	2e-11	78.2
tr:B0RAE2_CLAMS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.00	587	338	21	2	528	48	580	2e-11	78.2
rs:XP_010432895	PREDICTED: uncharacterized protein LOC104717073 [Camelina sativa].	24.50	551	334	24	32	536	501	1015	2e-11	78.6
rs:WP_018157186	DNA topoisomerase I [Demetria terragena].	21.87	631	381	20	2	571	4	583	2e-11	78.2
rs:WP_028430727	DNA topoisomerase I [Streptomyces sp. TAA204].	23.10	593	336	23	2	530	13	549	2e-11	78.2
rs:WP_006564731	DNA topoisomerase I [Helicobacter suis].	25.10	490	303	19	81	537	55	513	2e-11	77.8
rs:WP_008522909	DNA topoisomerase I [Jonquetella anthropi].	21.53	576	360	17	88	615	179	710	2e-11	78.2
rs:WP_036864134	DNA topoisomerase I [Prevotella bivia].	22.56	554	335	17	3	526	5	494	2e-11	78.2
rs:WP_024118415	DNA topoisomerase I [Helicobacter pylori].	22.69	639	404	21	3	614	4	579	2e-11	78.2
rs:WP_038268974	DNA topoisomerase I [Zhouia amylolytica].	24.44	540	321	22	3	521	5	478	2e-11	78.2
rs:WP_013399414	DNA topoisomerase I [Gardnerella vaginalis].	23.70	637	354	24	2	571	18	589	2e-11	78.2
rs:WP_006254729	DNA topoisomerase I [Alloprevotella tannerae].	21.68	535	343	15	3	520	8	483	2e-11	78.2
rs:WP_015199327	DNA topoisomerase I [Calothrix parietina].	22.15	605	389	18	3	566	4	567	2e-11	78.2
rs:WP_013448067	DNA topoisomerase I [Mycoplasma leachii].	22.88	625	382	26	46	625	36	605	2e-11	77.8
rs:WP_010019870	DNA topoisomerase I [Lactobacillus farciminis].	23.24	581	377	22	90	635	71	617	2e-11	78.2
rs:WP_007356210	MULTISPECIES: DNA topoisomerase I [Kamptonema].	22.94	571	358	16	3	530	4	535	2e-11	78.2
rs:WP_024332001	DNA topoisomerase I [Actinomyces neuii].	23.80	626	360	25	2	563	9	581	2e-11	78.2
rs:WP_028643525	DNA topoisomerase I [Nocardioides sp. URHA0020].	24.17	662	378	31	2	591	4	613	2e-11	78.2
rs:WP_028042355	DNA topoisomerase I [Candidatus Stoquefichus massiliensis].	24.44	495	307	21	164	629	142	598	2e-11	77.8
rs:WP_009782287	DNA topoisomerase I [Lyngbya sp. PCC 8106].	23.21	418	258	13	186	564	172	565	2e-11	78.2
rs:WP_034265900	DNA topoisomerase I, partial [Aminiphilus circumscriptus].	22.80	601	358	28	89	636	64	611	2e-11	77.8
tr:K2FXV5_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.66	588	358	22	77	614	53	605	2e-11	78.2
rs:XP_006272770	PREDICTED: DNA topoisomerase 3-alpha [Alligator mississippiensis].	23.09	485	302	18	188	634	156	607	2e-11	78.2
rs:XP_010447598	PREDICTED: uncharacterized protein LOC104730175 isoform X1 [Camelina sativa].	23.72	548	342	23	32	536	460	974	2e-11	78.6
rs:WP_028595587	DNA topoisomerase I [Paenibacillus assamensis].	22.79	566	375	18	103	636	80	615	2e-11	77.8
rs:WP_043584467	DNA topoisomerase I [Clavibacter michiganensis].	23.00	587	338	21	2	528	6	538	2e-11	78.2
rs:WP_029029760	DNA topoisomerase I [Salinarimonas rosea].	22.37	693	414	31	1	630	1	632	2e-11	78.2
tr:A0A0E0IGT1_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA09G02300.2};	21.21	693	424	28	3	621	65	709	2e-11	78.2
rs:XP_010229158	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Brachypodium distachyon].	23.47	426	257	14	188	585	20	404	2e-11	78.2
rs:WP_043265431	DNA topoisomerase I [Streptomyces sp. CT34].	23.44	593	332	22	2	530	14	548	2e-11	78.2
rs:WP_026328586	DNA topoisomerase I [Streptomyces sulphureus].	22.91	598	331	23	2	530	13	549	2e-11	78.2
rs:WP_044170579	DNA topoisomerase I [Ehrlichia chaffeensis].	23.90	749	441	31	1	684	1	685	2e-11	78.2
rs:XP_007801474	hypothetical protein EPUS_08478 [Endocarpon pusillum Z07020].	21.75	423	277	13	188	584	210	604	2e-11	77.8
rs:WP_032517299	hypothetical protein [Peptoclostridium difficile].	29.69	192	122	5	497	678	14	202	2e-11	74.7
rs:WP_015333594	DNA topoisomerase I [Fibrella aestuarina].	24.81	403	247	12	3	392	5	364	2e-11	78.2
rs:WP_034353657	DNA topoisomerase I [Helicobacter sp. MIT 09-6949].	23.60	623	380	22	48	614	4	586	2e-11	77.8
rs:WP_041438846	DNA topoisomerase I, partial [Synechococcus sp. JA-3-3Ab].	21.99	632	359	22	2	564	3	569	2e-11	78.2
tr:B7R9S8_9THEO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.62	463	278	20	90	518	85	510	2e-11	77.4
rs:WP_031788636	hypothetical protein [Staphylococcus aureus].	35.51	138	68	3	486	615	10	134	2e-11	74.7
rs:WP_012592797	DNA topoisomerase I [Methylocella silvestris].	23.62	686	412	28	1	629	1	631	2e-11	78.2
rs:WP_027404688	DNA topoisomerase I [Aphanizomenon flos-aquae].	22.04	608	374	18	3	560	4	561	2e-11	78.2
tr:J6FF50_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EJY17018.1}; Flags: Fragment;	33.33	177	112	3	52	222	3	179	2e-11	74.3
rs:WP_021057527	Topoisomerase IA, partial [Haloquadratum sp. J07HQX50].	25.79	411	235	20	3	370	7	390	2e-11	76.6
rs:WP_004336816	DNA topoisomerase I [Prevotella bivia].	22.56	554	335	17	3	526	5	494	2e-11	77.8
rs:XP_010447599	PREDICTED: uncharacterized protein LOC104730175 isoform X2 [Camelina sativa].	23.72	548	342	23	32	536	460	974	2e-11	78.2
tr:A0A0D3DH53_BRAOL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Bo7g115010.1};	22.99	648	399	28	32	618	909	1517	2e-11	78.2
rs:WP_038025549	DNA topoisomerase I [Tenacibaculum maritimum].	26.75	400	240	14	157	539	132	495	2e-11	77.8
rs:WP_003824719	DNA topoisomerase I [Eikenella corrodens].	21.26	602	389	20	76	630	53	616	2e-11	77.8
rs:WP_044503664	DNA topoisomerase I [Megasphaera sp. NP3].	21.57	677	412	23	3	630	57	663	2e-11	77.8
rs:WP_034055413	hypothetical protein, partial [Pseudomonas aeruginosa].	23.33	480	291	19	163	616	138	566	2e-11	77.4
rs:WP_045548636	DNA topoisomerase I [Nocardioides luteus].	23.31	652	354	28	2	577	4	585	2e-11	78.2
tr:J9Z7K0_LEPFM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.87	599	385	25	76	631	23	587	2e-11	77.8
rs:WP_007046121	DNA topoisomerase III [Subdoligranulum variabile].	35.11	131	84	1	497	627	14	143	2e-11	74.3
rs:WP_011715198	DNA topoisomerase I [Magnetococcus marinus].	22.06	612	390	23	76	629	52	634	2e-11	77.8
rs:WP_046700364	DNA topoisomerase I [Moraxella bovoculi].	24.36	390	250	12	187	560	209	569	2e-11	78.2
tr:X0RW50_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.99	646	397	27	77	673	101	701	2e-11	78.2
tr:Q2JWS9_SYNJA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.99	632	359	22	2	564	3	569	2e-11	77.8
tr:L8YCR4_TUPCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.33	493	291	19	188	634	219	670	2e-11	78.2
rs:WP_035153311	DNA topoisomerase I [Calothrix sp. 336/3].	22.10	620	367	18	3	560	4	569	2e-11	77.8
rs:WP_006727604	DNA topoisomerase I [Agrobacterium albertimagni].	22.46	659	408	27	38	630	16	637	2e-11	77.8
rs:WP_003787925	DNA topoisomerase I [Kingella kingae].	21.44	681	422	23	70	679	37	675	2e-11	77.8
rs:WP_028036917	DNA topoisomerase I [Candidatus Pelagibacter ubique].	21.75	570	352	17	1	534	1	512	2e-11	77.8
tr:A0A024GUU9_9STRA	SubName: Full=Albugo candida WGS project CAIX00000000 data, strain Ac Nc2, contig AcNc2_CONTIG_579_length_13152 {ECO:0000313|EMBL:CCI50569.1};	24.29	387	242	12	188	551	206	564	2e-11	77.8
rs:WP_046242733	DNA topoisomerase I [Hymenobacter sp. MIMtkLc17].	22.14	542	339	15	3	521	5	486	2e-11	77.8
rs:WP_012471296	DNA topoisomerase I [Geobacter lovleyi].	22.46	601	385	19	76	629	53	619	2e-11	77.8
rs:WP_034718510	DNA topoisomerase I [Chryseobacterium antarcticum].	24.52	624	377	23	3	604	5	556	2e-11	77.8
rs:WP_035916355	DNA topoisomerase I [Knoellia sinensis].	23.59	585	340	21	2	530	4	537	2e-11	77.8
tr:A4TWS2_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.22	693	419	27	1	630	1	636	2e-11	77.8
tr:I2GJD4_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.12	406	242	13	3	392	33	392	2e-11	77.8
rs:WP_024982273	DNA topoisomerase I [Flavobacterium succinicans].	24.58	533	328	20	3	521	5	477	2e-11	77.8
rs:WP_039203318	DNA topoisomerase I [Aphanizomenon flos-aquae].	22.20	608	373	19	3	560	4	561	2e-11	77.8
rs:WP_026414122	DNA topoisomerase I [Actinomadura oligospora].	24.28	593	325	24	2	530	20	552	2e-11	77.8
rs:WP_041321243	DNA topoisomerase I [Hyphomicrobium denitrificans].	24.85	656	377	31	55	630	27	646	2e-11	77.8
rs:WP_021849581	DNA topoisomerase [Firmicutes bacterium CAG:791].	22.54	630	405	21	90	673	67	659	2e-11	77.8
rs:WP_007599335	DNA topoisomerase I [Rhizobium sp. PDO1-076].	22.68	657	409	26	38	630	16	637	2e-11	77.8
rs:WP_014679529	DNA topoisomerase I [Solitalea canadensis].	23.75	518	345	14	76	580	53	533	2e-11	77.8
rs:WP_044002451	DNA topoisomerase I [Hymenobacter swuensis].	23.61	487	291	16	74	526	51	490	2e-11	77.8
rs:WP_028982117	DNA topoisomerase I [Sporocytophaga myxococcoides].	23.09	537	331	15	3	520	5	478	2e-11	77.8
rs:WP_038314451	DNA topoisomerase I [Kingella kingae].	21.44	681	422	23	70	679	37	675	2e-11	77.8
rs:WP_036448794	DNA topoisomerase I, partial [Mycoplasma pirum].	21.30	615	386	19	74	629	52	627	2e-11	77.4
rs:XP_011982803	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Ovis aries musimon].	22.90	489	297	17	188	634	239	689	2e-11	77.8
rs:WP_011738364	DNA topoisomerase I [Candidatus Ruthia magnifica].	27.61	326	207	8	77	391	54	361	2e-11	77.8
rs:WP_043695374	DNA topoisomerase I [Synechococcus sp. KORDI-49].	22.97	518	320	18	100	572	91	574	2e-11	77.8
tr:A0A024W0X4_PLAFA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETW34589.1};	23.70	637	360	24	3	557	7	599	2e-11	77.4
tr:S2UTZ2_LACPA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.12	510	320	18	154	629	39	515	2e-11	77.4
tr:W6MQ22_9ASCO	SubName: Full=Genomic scaffold, Kuraishia_capsulata_scaffold_5 {ECO:0000313|EMBL:CDK28428.1};	21.80	633	406	21	3	580	5	603	2e-11	77.4
rs:WP_038302802	DNA topoisomerase I [Kingella kingae].	21.44	681	422	23	70	679	37	675	2e-11	77.8
rs:WP_036886207	DNA topoisomerase I [Prevotella bivia].	22.74	554	334	18	3	526	5	494	2e-11	77.8
rs:XP_005402335	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Chinchilla lanigera].	23.67	469	284	17	188	619	239	670	2e-11	77.8
rs:XP_007848663	dna topoisomerase [Moniliophthora roreri MCA 2997].	22.12	633	395	24	3	586	4	587	2e-11	77.4
rs:WP_008678395	DNA topoisomerase I [Clostridium sp. 7_2_43FAA].	24.64	552	333	20	103	616	80	586	2e-11	77.4
rs:WP_033613498	DNA topoisomerase, partial [Enterococcus faecium].	31.51	219	126	9	117	317	4	216	2e-11	74.3
gp:CP002608_247	DNA topoisomerase [Chlamydophila pecorum E58]	23.40	577	341	21	3	534	12	532	2e-11	77.8
rs:XP_006161709	PREDICTED: DNA topoisomerase 3-alpha [Tupaia chinensis].	23.33	493	291	19	188	634	239	690	2e-11	77.8
tr:A0A0D9YS72_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OGLUM02G16580.3};	22.76	624	370	27	39	610	309	872	2e-11	77.8
rs:WP_013143636	reverse gyrase [Staphylothermus hellenicus].	25.31	407	221	16	186	561	913	1267	2e-11	77.8
rs:WP_020172467	DNA topoisomerase I [Gordonia polyisoprenivorans].	24.66	592	332	23	2	530	17	557	2e-11	77.8
tr:D4K9W2_9FIRM	SubName: Full=Draft genome {ECO:0000313|EMBL:CBL01625.1};	33.63	113	59	4	2	107	4	107	2e-11	72.4
rs:WP_020478602	hypothetical protein [Myxococcus xanthus].	22.76	624	386	27	76	640	506	1092	2e-11	77.8
rs:XP_008162975	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Chrysemys picta bellii].	24.30	465	286	16	188	619	241	672	2e-11	77.8
rs:XP_008443146	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Cucumis melo].	22.48	645	412	23	3	599	10	614	2e-11	77.8
rs:WP_015124680	DNA topoisomerase I [Synechococcus sp. PCC 6312].	22.81	627	374	20	3	574	4	575	2e-11	77.8
tr:A0A091PE50_HALAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.39	488	292	19	188	634	221	672	2e-11	77.8
rs:XP_009841734	hypothetical protein H257_15346 [Aphanomyces astaci].	24.87	394	243	12	188	560	219	580	2e-11	77.8
rs:WP_004124073	DNA topoisomerase I [Gardnerella vaginalis].	23.62	635	357	23	2	571	6	577	2e-11	77.8
rs:WP_019879161	hypothetical protein [Succinispira mobilis].	23.15	648	400	26	3	616	5	588	2e-11	77.4
rs:WP_009797455	DNA topoisomerase I [Nitrobacter sp. Nb-311A].	22.54	692	412	29	1	629	1	631	2e-11	77.8
rs:XP_007247893	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Astyanax mexicanus].	23.53	391	256	10	188	564	237	598	2e-11	77.4
rs:WP_038057543	topoisomerase [Thermodesulfobacterium hydrogeniphilum].	24.24	524	315	17	82	582	710	1174	2e-11	77.8
rs:WP_019388943	DNA topoisomerase I [Kingella kingae].	21.44	681	422	23	70	679	37	675	2e-11	77.4
rs:WP_041136416	DNA topoisomerase I [Sulfurovum sp. AS07-7].	24.30	675	383	27	3	629	4	598	2e-11	77.4
tr:G3VJM6_SARHA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.23	465	291	16	188	619	141	572	2e-11	77.8
rs:XP_004502963	PREDICTED: DNA topoisomerase 3-alpha [Cicer arietinum].	23.06	633	396	26	3	585	9	600	2e-11	77.8
rs:WP_039879571	DNA topoisomerase I [Jonquetella anthropi].	21.53	576	360	17	88	615	179	710	2e-11	77.4
rs:WP_035567454	DNA topoisomerase I [Hymenobacter sp. IS2118].	22.37	541	339	14	3	521	5	486	2e-11	77.4
rs:WP_009092305	DNA topoisomerase III, partial [Elizabethkingia anophelis].	34.38	192	113	7	488	673	1	185	2e-11	73.9
rs:WP_018536494	DNA topoisomerase I [Streptomyces sp. MspMP-M5].	23.62	597	327	22	2	530	14	549	2e-11	77.8
rs:WP_021187238	DNA topoisomerase I [Helicobacter pylori].	23.46	486	316	15	82	537	61	520	2e-11	77.0
tr:A0A078CBA8_BRANA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.99	648	399	28	32	618	369	977	2e-11	77.8
rs:WP_021736657	DNA topoisomerase I [Acidaminococcus sp. BV3L6].	21.28	639	424	18	3	616	4	588	2e-11	77.4
rs:WP_039246338	DNA topoisomerase I, partial [Clostridium haemolyticum].	33.33	147	93	3	77	219	3	148	2e-11	73.9
rs:XP_011982804	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Ovis aries musimon].	22.90	489	297	17	188	634	156	606	2e-11	77.8
rs:WP_014358786	DNA topoisomerase I [Gordonia polyisoprenivorans].	24.66	592	332	23	2	530	17	557	2e-11	77.8
rs:WP_025767428	hypothetical protein [Vibrio parahaemolyticus].	22.50	729	456	26	1	684	1	665	2e-11	77.8
rs:WP_033368960	DNA topoisomerase I [Selenomonas bovis].	23.71	561	366	20	90	616	102	634	2e-11	77.4
rs:XP_011652135	PREDICTED: DNA topoisomerase 3-alpha [Cucumis sativus].	22.33	645	413	23	3	599	10	614	2e-11	77.8
rs:XP_008162976	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Chrysemys picta bellii].	24.30	465	286	16	188	619	153	584	2e-11	77.8
rs:WP_013748907	reverse gyrase [Pyrococcus sp. NA2].	24.04	441	245	15	162	574	826	1204	2e-11	77.8
rs:WP_003670294	topoisomerase I [Moraxella catarrhalis].	23.09	485	282	17	187	629	207	642	3e-11	77.4
rs:WP_046870408	DNA topoisomerase I [Clostridium sporogenes].	25.95	578	335	25	83	616	60	588	3e-11	77.4
rs:XP_005464354	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Oreochromis niloticus].	21.87	567	359	19	38	564	42	564	3e-11	77.4
rs:WP_041651541	DNA topoisomerase I [Anaplasma centrale].	23.62	690	403	31	1	629	1	627	3e-11	77.4
rs:WP_036294629	hypothetical protein, partial [Methylobacter whittenburyi].	23.57	488	298	16	77	528	56	504	3e-11	77.0
tr:R5Q3X4_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.38	650	387	26	2	614	4	579	3e-11	77.4
rs:WP_019207142	hypothetical protein [Phocaeicola abscessus].	23.21	461	304	14	77	520	54	481	3e-11	77.4
rs:WP_009994256	DNA topoisomerase I [Gardnerella vaginalis].	23.70	637	354	24	2	571	6	577	3e-11	77.4
rs:WP_040005810	DNA topoisomerase I [Fibrisoma limi].	25.12	406	242	13	3	392	5	364	3e-11	77.4
rs:XP_004965230	PREDICTED: uncharacterized protein LOC101772280 isoform X2 [Setaria italica].	22.27	642	385	26	39	610	333	930	3e-11	77.8
rs:WP_040163391	DNA topoisomerase I [bacterium SIT7].	22.58	682	382	26	2	593	7	632	3e-11	77.4
rs:XP_005947077	PREDICTED: DNA topoisomerase 3-alpha-like isoform X2 [Haplochromis burtoni].	23.09	498	288	19	188	634	176	629	3e-11	77.4
rs:WP_034344388	DNA topoisomerase I [Deinococcus misasensis].	24.17	575	342	20	3	530	5	532	3e-11	77.4
tr:J9CX79_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EJX04866.1};	24.28	593	363	23	36	604	15	545	3e-11	77.4
rs:WP_027537100	DNA topoisomerase I [Bradyrhizobium sp. URHA0002].	23.20	582	341	25	1	537	1	521	3e-11	77.4
rs:WP_034073375	hypothetical protein, partial [Pseudomonas aeruginosa].	22.96	479	294	18	163	616	138	566	3e-11	77.0
rs:WP_045472181	DNA topoisomerase I [Winogradskyella sp. PG-2].	27.39	387	228	14	154	521	128	480	3e-11	77.4
rs:WP_025606038	DNA topoisomerase I [Pontibacter actiniarum].	24.26	544	351	16	74	596	51	554	3e-11	77.4
tr:X2NB07_SALEN	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AHO22244.1};	38.69	137	73	5	89	215	1	136	3e-11	74.3
rs:WP_010619796	DNA topoisomerase I [Lactobacillus malefermentans].	23.04	573	377	20	88	629	74	613	3e-11	77.4
rs:WP_040349776	DNA topoisomerase, partial [Anaerococcus tetradius].	40.71	113	64	1	467	579	2	111	3e-11	72.4
rs:WP_010753926	DNA topoisomerase 1 [Enterococcus asini].	23.20	582	383	22	88	635	63	614	3e-11	77.4
tr:Q1D812_MYXXD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.76	624	386	27	76	640	514	1100	3e-11	77.8
tr:N0BDX9_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.85	656	377	31	55	630	57	676	3e-11	77.4
rs:XP_001556935	hypothetical protein BC1G_04651 [Botrytis cinerea B05.10].	23.71	388	252	13	150	520	98	458	3e-11	77.0
rs:XP_003763121	PREDICTED: DNA topoisomerase 3-alpha, partial [Sarcophilus harrisii].	23.23	465	291	16	188	619	134	565	3e-11	77.4
tr:D1AS91_ANACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.62	690	403	31	1	629	2	628	3e-11	77.4
rs:XP_010568690	PREDICTED: DNA topoisomerase 3-alpha [Haliaeetus leucocephalus].	24.39	488	292	19	188	634	235	686	3e-11	77.4
rs:WP_041125153	DNA topoisomerase I, partial [Sulfurovum sp. FS06-10].	22.60	646	399	23	3	615	4	581	3e-11	77.4
tr:W7D7J3_9LIST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	23.42	427	269	16	237	635	24	420	3e-11	76.6
rs:WP_032883712	DNA topoisomerase I [Clostridium sporogenes].	25.95	578	335	25	83	616	60	588	3e-11	77.4
rs:WP_040109633	DNA topoisomerase I [Clostridium botulinum].	25.95	578	335	25	83	616	60	588	3e-11	77.4
rs:WP_022740713	hypothetical protein [Lachnospiraceae bacterium COE1].	44.30	79	44	0	130	208	10	88	3e-11	72.0
rs:XP_005752308	PREDICTED: DNA topoisomerase 3-alpha-like isoform X2 [Pundamilia nyererei].	23.09	498	288	19	188	634	176	629	3e-11	77.4
rs:WP_023984273	DNA topoisomerase I [Prevotella oralis].	22.77	606	362	22	3	578	5	534	3e-11	77.4
rs:WP_008355071	DNA topoisomerase I [Nocardioidaceae bacterium Broad-1].	22.89	651	358	27	2	577	4	585	3e-11	77.4
tr:H2MFK0_ORYLA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.27	477	277	18	188	619	207	639	3e-11	77.4
rs:WP_021757590	DNA topoisomerase [Chlamydia pecorum].	23.40	577	341	21	3	534	5	525	3e-11	77.4
rs:WP_012692721	DNA topoisomerase I [Deinococcus deserti].	24.06	586	334	23	3	530	5	537	3e-11	77.4
tr:G9EXY9_CLOSG	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.95	578	335	25	83	616	64	592	3e-11	77.0
tr:W5NPJ8_SHEEP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.90	489	297	17	188	634	241	691	3e-11	77.4
rs:WP_005865502	DNA topoisomerase I [Bartonella alsatica].	23.15	691	411	28	1	629	1	633	3e-11	77.4
tr:H3CL93_TETNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.40	470	284	17	188	619	207	638	3e-11	77.4
tr:W5NPJ3_SHEEP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.09	485	301	17	188	634	258	708	3e-11	77.4
rs:WP_008449636	DNA topoisomerase I [Prevotella amnii].	23.68	625	376	24	3	596	5	559	3e-11	77.4
rs:XP_005947076	PREDICTED: DNA topoisomerase 3-alpha-like isoform X1 [Haplochromis burtoni].	23.09	498	288	19	188	634	256	709	3e-11	77.4
rs:WP_000596183	hypothetical protein, partial [Escherichia coli].	30.77	182	121	3	497	676	4	182	3e-11	73.6
rs:YP_008052594	DNA topoisomerase I [Phaeocystis globosa virus].	24.55	497	289	20	74	527	50	503	3e-11	77.4
rs:WP_006282731	DNA topoisomerase I [Prevotella bryantii].	22.96	540	331	17	3	520	5	481	3e-11	77.4
rs:WP_015501246	DNA topoisomerase I [Octadecabacter antarcticus].	22.48	565	351	20	1	534	1	509	3e-11	77.4
rs:WP_006372355	DNA topoisomerase I [Gordonia polyisoprenivorans].	24.66	592	332	23	2	530	17	557	3e-11	77.4
gp:HG974234_6437	DNA topoisomerase I, plasmid [Pseudomonas aeruginosa]	23.40	483	293	19	163	619	138	569	3e-11	77.0
rs:WP_010831330	DNA topoisomerase I [Nocardioides sp. CF8].	21.92	657	396	23	2	591	4	610	3e-11	77.4
rs:WP_012953898	DNA topoisomerase I [Candidatus Atelocyanobacterium thalassa].	22.60	624	381	22	3	574	4	577	3e-11	77.4
rs:XP_008328484	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Cynoglossus semilaevis].	22.54	497	292	19	188	634	256	709	3e-11	77.4
tr:J2MMG4_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Precursor;	29.11	237	148	6	186	409	196	425	3e-11	76.6
rs:WP_030019286	DNA topoisomerase I [Streptomyces monomycini].	23.19	595	332	22	2	530	14	549	3e-11	77.4
rs:WP_013302714	DNA topoisomerase [Ignisphaera aggregans].	24.55	558	324	23	87	599	722	1227	3e-11	77.4
rs:WP_038010604	DNA topoisomerase I [Tannerella sp. oral taxon BU063].	25.14	537	324	19	3	520	5	482	3e-11	77.4
rs:XP_009919077	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Haliaeetus albicilla].	24.39	488	292	19	188	634	227	678	3e-11	77.4
rs:WP_038305813	DNA topoisomerase I [Kingella kingae].	21.35	665	420	22	76	679	53	675	3e-11	77.0
rs:WP_019707577	DNA topoisomerase I [Streptomyces xinghaiensis].	22.67	591	341	21	2	530	13	549	3e-11	77.4
tr:X2I8D7_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	23.87	532	346	18	80	574	52	561	3e-11	77.0
rs:WP_020719565	hypothetical protein [Acidobacteriaceae bacterium KBS 96].	22.90	620	374	24	76	629	53	634	3e-11	77.4
rs:WP_033799367	DNA topoisomerase I, partial [Bacillus pseudomycoides].	26.30	308	198	11	384	675	1	295	3e-11	75.5
rs:WP_027376008	DNA topoisomerase I [Chryseobacterium palustre].	25.78	415	260	12	3	410	5	378	3e-11	77.4
tr:S9VQR0_SCHCR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.49	618	381	22	3	565	4	578	3e-11	77.0
rs:XP_004713017	PREDICTED: DNA topoisomerase 3-alpha [Echinops telfairi].	23.82	466	281	17	188	616	239	667	3e-11	77.4
rs:WP_017626847	DNA topoisomerase I [Nocardiopsis chromatogenes].	22.70	586	346	21	2	530	24	559	3e-11	77.4
tr:F6Z0N0_ORNAN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.66	465	290	16	188	619	179	611	3e-11	77.4
rs:XP_011031137	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Populus euphratica].	22.19	631	403	23	3	585	5	595	3e-11	77.4
tr:J9J536_9SPIT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EJY84543.1};	24.28	416	253	13	188	573	156	539	3e-11	77.4
rs:WP_013526780	DNA topoisomerase I [Mycoplasma fermentans].	24.43	528	321	18	73	564	50	535	3e-11	77.0
rs:WP_024650439	hypothetical protein [Pseudomonas syringae].	23.50	383	249	10	163	526	135	492	3e-11	77.0
rs:WP_044069760	hypothetical protein [Pseudomonas aeruginosa].	23.14	484	293	19	163	619	138	569	3e-11	76.6
rs:WP_042857253	DNA topoisomerase III, partial [Staphylococcus aureus].	34.59	159	87	6	3	150	4	156	3e-11	73.2
rs:XP_004071982	PREDICTED: DNA topoisomerase 3-alpha [Oryzias latipes].	22.89	498	289	19	188	634	257	710	3e-11	77.4
rs:WP_038329203	DNA topoisomerase I [Kingella kingae].	21.44	681	422	23	70	679	37	675	3e-11	77.0
rs:WP_034229261	hypothetical protein, partial [Lachnospiraceae bacterium 3-1].	31.25	112	61	4	3	107	5	107	3e-11	72.0
rs:WP_043165606	DNA topoisomerase I [Bifidobacterium callitrichos].	23.05	655	356	24	2	571	6	597	3e-11	77.4
rs:WP_033178772	DNA topoisomerase I [Mycoplasma anseris].	23.19	595	367	21	73	629	50	592	3e-11	76.6
rs:XP_011011407	PREDICTED: DNA topoisomerase 3-alpha-like isoform X2 [Populus euphratica].	22.19	631	403	23	3	585	5	595	3e-11	77.4
rs:WP_011472692	DNA topoisomerase I [Rhodopseudomonas palustris].	23.32	686	415	31	1	629	1	632	3e-11	77.4
rs:XP_008328483	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Cynoglossus semilaevis].	22.54	497	292	19	188	634	256	709	3e-11	77.4
rs:XP_009919078	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Haliaeetus albicilla].	24.39	488	292	19	188	634	163	614	3e-11	77.4
rs:XP_005752307	PREDICTED: DNA topoisomerase 3-alpha-like isoform X1 [Pundamilia nyererei].	23.09	498	288	19	188	634	256	709	3e-11	77.4
rs:XP_004965229	PREDICTED: uncharacterized protein LOC101772280 isoform X1 [Setaria italica].	22.27	642	385	26	39	610	333	930	3e-11	77.4
rs:WP_009789155	DNA topoisomerase I [Synechococcus sp. BL107].	21.79	537	349	16	77	572	68	574	3e-11	77.0
rs:WP_041596475	DNA topoisomerase I, partial [Halothece sp. PCC 7418].	22.51	622	382	17	3	574	4	575	3e-11	77.0
rs:XP_005468449	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Oreochromis niloticus].	23.45	499	285	19	188	634	176	629	3e-11	77.4
tr:A0A078AG43_STYLE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.60	356	237	9	252	598	469	798	3e-11	77.4
rs:XP_011031138	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Populus euphratica].	22.19	631	403	23	3	585	5	595	3e-11	77.0
rs:WP_038334579	DNA topoisomerase I [Kingella kingae].	21.44	681	422	23	70	679	37	675	3e-11	77.0
rs:XP_011982805	PREDICTED: DNA topoisomerase 3-alpha isoform X4 [Ovis aries musimon].	22.90	489	297	17	188	634	76	526	3e-11	77.0
tr:A0A093C8L8_9AVES	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.97	484	299	18	188	634	221	672	3e-11	77.4
rs:WP_014925151	DNA topoisomerase I [Gordonia sp. KTR9].	23.98	588	339	21	2	530	16	554	3e-11	77.4
rs:XP_006285818	hypothetical protein CARUB_v10007294mg [Capsella rubella].	23.54	548	343	23	32	536	497	1011	3e-11	77.4
tr:C4XEP1_MYCFP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00003390}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.43	528	321	18	73	564	53	538	3e-11	76.6
rs:WP_013166327	DNA topoisomerase I [Starkeya novella].	22.16	686	423	28	1	629	1	632	3e-11	77.0
rs:XP_009414693	PREDICTED: DNA topoisomerase 3-beta isoform X3 [Musa acuminata subsp. malaccensis].	22.90	345	225	10	252	586	193	506	3e-11	77.0
rs:XP_005964996	PREDICTED: DNA topoisomerase 3-alpha [Pantholops hodgsonii].	23.30	485	300	17	188	634	280	730	3e-11	77.4
rs:WP_038604242	DNA topoisomerase I, partial [Rickettsiales bacterium Ac37b].	22.61	681	425	25	1	629	1	631	3e-11	77.0
sp:TOP1P_MIMIV	RecName: Full=DNA topoisomerase 1 type prokaryotic; EC=5.99.1.2;	25.00	480	278	21	90	521	64	509	3e-11	77.0
tr:R9IKM0_9FIRM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOS22504.1};	31.25	112	61	4	3	107	4	106	3e-11	71.6
rs:WP_042744564	topoisomerase I, partial [Oenococcus oeni].	28.71	209	127	7	470	664	1	201	3e-11	73.9
gpu:CP009528_2347	DNA topoisomerase I [Methanosarcina barkeri MS]	23.19	595	341	23	90	611	92	643	3e-11	77.0
rs:WP_013405856	DNA topoisomerase I [Halanaerobium hydrogeniformans].	23.81	672	391	26	3	629	8	603	3e-11	77.0
rs:WP_015929895	DNA topoisomerase I [Methylobacterium nodulans].	21.80	688	422	25	1	629	1	631	3e-11	77.0
rs:XP_007766399	prokaryotic type I DNA topoisomerase [Coniophora puteana RWD-64-598 SS2].	23.60	623	371	24	3	576	4	570	4e-11	77.0
rs:WP_033628389	DNA topoisomerase, partial [Enterococcus faecalis].	28.95	190	119	4	502	675	1	190	4e-11	73.6
rs:WP_032133092	DNA topoisomerase I [Kingella kingae].	21.44	681	422	23	70	679	37	675	4e-11	77.0
rs:WP_014158778	DNA topoisomerase I [Blattabacterium sp. (Mastotermes darwiniensis)].	26.44	537	306	23	3	520	5	471	4e-11	77.0
rs:YP_003969716	putative DNA topoisomerase IA [Cafeteria roenbergensis virus BV-PW1].	24.58	541	326	17	1	523	1	477	4e-11	77.0
rs:WP_031633366	hypothetical protein, partial [Pseudomonas aeruginosa].	23.40	483	293	19	163	619	138	569	4e-11	76.6
tr:M0WQP5_HORVD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.88	640	395	23	3	585	11	602	4e-11	77.0
tr:I1GZ20_BRADI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.48	525	321	18	64	536	112	602	4e-11	77.0
tr:A0A0D2E9R9_9EURO	SubName: Full=Strain CBS 118157 unplaced genomic scaffold supercont1.5, whole genome shotgun sequence {ECO:0000313|EMBL:KIW52113.1};	23.08	481	296	17	150	591	165	610	4e-11	76.6
rs:WP_008757996	DNA topoisomerase I [Rhodobacteraceae bacterium KLH11].	21.94	588	348	19	1	534	1	531	4e-11	77.0
rs:WP_034438608	DNA topoisomerase I [Clostridiales bacterium S5-A11].	23.77	652	390	26	3	616	4	586	4e-11	77.0
rs:WP_021875555	DNA topoisomerase [Clostridium chauvoei].	25.31	561	318	25	103	616	80	586	4e-11	77.0
rs:WP_036788982	DNA topoisomerase I [Porphyromonas canoris].	23.04	638	390	22	3	617	5	564	4e-11	77.0
rs:WP_038321536	DNA topoisomerase I [Kingella kingae].	21.44	681	422	23	70	679	37	675	4e-11	77.0
rs:WP_041594206	DNA topoisomerase I [Mycoplasma fermentans].	24.43	528	321	18	73	564	50	535	4e-11	76.6
rs:WP_026644146	DNA topoisomerase I [Bifidobacterium pseudolongum].	21.79	624	387	19	2	571	6	582	4e-11	77.0
rs:WP_031655094	hypothetical protein, partial [Pseudomonas aeruginosa].	23.33	480	291	19	163	616	138	566	4e-11	76.6
rs:XP_011011406	PREDICTED: DNA topoisomerase 3-alpha-like isoform X1 [Populus euphratica].	22.19	631	403	23	3	585	5	595	4e-11	77.0
rs:WP_036865838	DNA topoisomerase I [Prevotella bivia].	22.98	557	329	18	3	526	5	494	4e-11	77.0
rs:XP_011063790	PREDICTED: DNA topoisomerase 3-alpha-like [Acromyrmex echinatior].	21.48	461	303	12	188	619	253	683	4e-11	77.0
rs:WP_042159536	hypothetical protein, partial [Pseudomonas aeruginosa].	23.40	483	293	19	163	619	138	569	4e-11	76.6
rs:XP_005402336	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Chinchilla lanigera].	23.67	469	284	17	188	619	110	541	4e-11	77.0
rs:WP_005637485	DNA topoisomerase I [Parabacteroides merdae].	22.39	536	337	16	3	520	5	479	4e-11	77.0
tr:A0A0C3PNK5_PISTI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.99	648	393	29	3	591	4	604	4e-11	77.0
tr:M3RT82_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	22.91	467	309	12	99	537	77	520	4e-11	76.6
tr:A0A0E0NQ38_ORYRU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ORUFI03G04550.2};	23.37	445	269	18	3	396	13	436	4e-11	77.0
tr:G1XWN3_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.75	639	403	20	55	629	23	628	4e-11	77.0
rs:WP_028297149	DNA topoisomerase I [Olivibacter sitiensis].	24.11	477	304	16	74	526	51	493	4e-11	77.0
rs:WP_034852229	DNA topoisomerase I [Inquilinus limosus].	22.01	636	407	23	55	630	30	636	4e-11	77.0
rs:XP_009403000	PREDICTED: DNA topoisomerase 3-alpha [Musa acuminata subsp. malaccensis].	22.97	418	269	13	188	585	222	606	4e-11	77.0
tr:A0A0E0JZS5_ORYPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OPUNC02G14710.5};	22.92	602	357	26	64	610	415	964	4e-11	77.0
tr:K9YA52_HALP7	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.51	622	382	17	3	574	4	575	4e-11	77.0
rs:WP_019491917	DNA topoisomerase I [Calothrix sp. PCC 7103].	24.29	564	331	20	100	610	82	602	4e-11	76.6
rs:XP_008443145	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Cucumis melo].	22.48	645	412	23	3	599	10	614	4e-11	77.0
tr:A0A0B8PGN0_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAM65461.1};	28.93	242	150	10	1	231	1	231	4e-11	73.9
rs:WP_013354513	DNA topoisomerase I [Mycoplasma fermentans].	24.43	528	321	18	73	564	50	535	4e-11	76.6
tr:A0A0E0CVM3_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OMERI03G04540.2};	23.37	445	269	18	3	396	14	437	4e-11	77.0
rs:WP_028841534	topoisomerase [Thermodesulfobacterium hveragerdense].	24.80	512	298	19	82	573	699	1143	4e-11	77.0
rs:XP_008599298	DNA topoisomerase [Beauveria bassiana ARSEF 2860].	22.32	560	352	21	3	520	4	522	4e-11	76.6
rs:WP_001908493	DNA topoisomerase I [Helicobacter pylori].	22.91	467	309	12	99	537	9	452	4e-11	76.3
rs:WP_004219309	DNA topoisomerase I [Bifidobacterium animalis].	22.30	583	351	19	2	530	6	540	4e-11	77.0
rs:WP_038307892	DNA topoisomerase I [Kingella kingae].	21.44	681	422	23	70	679	37	675	4e-11	76.6
rs:XP_004612924	PREDICTED: DNA topoisomerase 3-alpha [Sorex araneus].	23.87	465	288	16	188	619	222	653	4e-11	77.0
rs:WP_028487358	DNA topoisomerase I [Thiomicrospira chilensis].	22.55	541	329	18	3	520	4	477	4e-11	77.0
rs:WP_034073736	hypothetical protein, partial [Pseudomonas aeruginosa].	23.40	483	293	19	163	619	138	569	4e-11	76.3
rs:WP_039634246	DNA topoisomerase I [Streptomyces sp. 769].	23.31	592	335	22	2	530	14	549	4e-11	77.0
rs:XP_004357934	DNA topoisomerase III [Dictyostelium fasciculatum].	21.97	719	450	28	3	659	30	699	4e-11	76.6
rs:WP_004112809	DNA topoisomerase I [Gardnerella vaginalis].	23.70	637	354	24	2	571	6	577	4e-11	77.0
rs:WP_038320683	DNA topoisomerase I [Kingella kingae].	21.44	681	422	23	70	679	37	675	4e-11	76.6
rs:WP_015117455	DNA topoisomerase I [Rivularia sp. PCC 7116].	22.80	557	347	16	100	610	82	601	4e-11	76.6
tr:D3R3C1_BIFAB	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.30	583	351	19	2	530	17	551	4e-11	77.0
tr:A0A0E0NQ41_ORYRU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ORUFI03G04550.5};	23.37	445	269	18	3	396	13	436	4e-11	77.0
rs:WP_045354101	topoisomerase I, partial [Lactobacillus plantarum].	29.85	134	92	1	461	592	2	135	4e-11	73.6
rs:WP_005647008	DNA topoisomerase I [Parabacteroides merdae].	22.39	536	337	16	3	520	5	479	4e-11	76.6
rs:XP_003351627	TOP3 protein [Sordaria macrospora k-hell].	23.56	505	324	20	46	524	6	474	4e-11	76.6
rs:WP_014553125	DNA topoisomerase I [Halanaerobium praevalens].	23.17	587	366	21	83	629	63	604	4e-11	76.6
rs:WP_013695829	DNA topoisomerase I [Candidatus Pelagibacter sp. IMCC9063].	24.14	642	374	30	1	591	1	580	4e-11	76.6
tr:A0A077FJB6_9RICK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.61	681	425	25	1	629	1	631	4e-11	76.6
rs:WP_022542520	DNA topoisomerase I [Bifidobacterium animalis].	22.30	583	351	19	2	530	6	540	4e-11	77.0
rs:XP_009137997	PREDICTED: uncharacterized protein LOC103862037 isoform X1 [Brassica rapa].	23.46	648	396	30	32	618	381	989	4e-11	77.0
rs:WP_024541650	DNA topoisomerase I [Bifidobacterium choerinum].	21.66	651	389	20	2	580	6	607	4e-11	77.0
rs:WP_004806974	DNA topoisomerase I [Actinomyces neuii].	23.27	623	367	25	2	563	9	581	4e-11	77.0
rs:WP_019668894	DNA topoisomerase I [Eudoraea adriatica].	27.06	436	265	14	103	521	80	479	4e-11	76.6
tr:A0A0A2VXF1_BEABA	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:KGQ12576.1};	22.32	560	352	21	3	520	4	522	4e-11	76.6
tr:A0A0E0CKE6_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OMERI02G16280.5};	22.56	625	370	27	39	610	310	873	4e-11	77.0
rs:WP_003123327	DNA topoisomerase I [Pseudomonas aeruginosa].	22.82	517	282	19	74	537	59	511	4e-11	76.6
rs:WP_036825562	DNA topoisomerase I, partial [Photobacterium sanctipauli].	24.74	380	230	12	277	633	1	347	4e-11	76.3
rs:WP_031757110	hypothetical protein, partial [Pseudomonas aeruginosa].	23.33	480	291	19	163	616	138	566	4e-11	76.3
rs:WP_033799342	DNA topoisomerase I, partial [Bacillus pseudomycoides].	26.30	308	198	11	384	675	1	295	4e-11	75.1
rs:XP_005468447	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Oreochromis niloticus].	23.45	499	285	19	188	634	256	709	4e-11	77.0
rs:XP_003465949	PREDICTED: DNA topoisomerase 3-alpha [Cavia porcellus].	22.71	480	300	16	188	629	239	685	4e-11	77.0
rs:XP_008937408	PREDICTED: DNA topoisomerase 3-alpha, partial [Merops nubicus].	24.73	465	284	18	188	619	213	644	4e-11	77.0
tr:K1SEB5_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC55898.1}; Flags: Fragment;	30.99	213	111	8	3	197	5	199	4e-11	73.2
tr:A0A094WEU5_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.67	600	385	25	76	631	23	587	4e-11	76.6
rs:XP_006412616	hypothetical protein EUTSA_v10024242mg [Eutrema salsugineum].	23.12	640	408	29	32	618	418	1026	4e-11	77.0
tr:A0A0E0K968_ORYPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OPUNC03G04550.1};	23.57	437	278	17	3	396	15	438	4e-11	76.6
rs:WP_004118179	DNA topoisomerase I [Gardnerella vaginalis].	24.02	637	352	25	2	571	6	577	4e-11	76.6
rs:WP_034904331	DNA topoisomerase I [Campylobacter sp. MIT 97-5078].	30.11	269	153	9	75	323	50	303	4e-11	76.6
rs:XP_008443143	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Cucumis melo].	22.48	645	412	23	3	599	10	614	5e-11	76.6
rs:WP_038315269	DNA topoisomerase I [Kingella kingae].	21.26	682	422	24	70	679	37	675	5e-11	76.6
rs:XP_006682765	hypothetical protein BATDEDRAFT_14853, partial [Batrachochytrium dendrobatidis JAM81].	21.66	614	391	20	3	573	2	568	5e-11	76.3
tr:A0A060D024_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	23.30	485	319	13	82	537	61	521	5e-11	76.3
rs:WP_022321949	DNA topoisomerase [Parabacteroides merdae CAG:48].	22.39	536	337	16	3	520	5	479	5e-11	76.6
rs:WP_047207619	DNA topoisomerase I [Mycoplasma hominis].	23.83	596	362	23	73	629	50	592	5e-11	76.3
rs:XP_007247892	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Astyanax mexicanus].	23.70	405	265	11	188	577	237	612	5e-11	77.0
rs:WP_021756983	DNA topoisomerase [Chlamydia pecorum].	23.40	577	341	21	3	534	5	525	5e-11	76.6
rs:XP_010073739	PREDICTED: DNA topoisomerase 3-alpha [Pterocles gutturalis].	23.97	484	299	18	188	634	241	692	5e-11	77.0
tr:C2CGU4_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEI83208.1}; Flags: Fragment;	42.27	97	55	1	130	226	3	98	5e-11	71.2
tr:A0A024GV12_9STRA	SubName: Full=Albugo candida WGS project CAIX00000000 data, strain Ac Nc2, contig AcNc2_CONTIG_579_length_13152 {ECO:0000313|EMBL:CCI50570.1};	24.29	387	242	12	188	551	206	564	5e-11	76.6
tr:A0A0E0JZS2_ORYPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OPUNC02G14710.2};	22.48	614	369	26	64	610	415	988	5e-11	77.0
tr:J6Y817_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJY35264.1}; Flags: Fragment;	30.07	143	98	1	413	553	16	158	5e-11	72.4
rs:WP_020308961	DNA topoisomerase I [Pseudomonas stutzeri].	22.71	568	350	20	100	631	75	589	5e-11	76.6
rs:WP_018338119	DNA topoisomerase I [Butyricimonas synergistica].	25.06	403	248	11	3	392	5	366	5e-11	76.6
rs:WP_040157647	DNA topoisomerase I [Mobilicoccus sp. SIT2].	22.54	630	384	21	2	572	8	592	5e-11	76.6
tr:K9INH6_DESRO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.09	485	296	17	188	631	239	687	5e-11	76.6
rs:WP_022253962	DNA topoisomerase [Firmicutes bacterium CAG:466].	22.37	438	257	15	251	630	16	428	5e-11	75.9
rs:WP_046701437	DNA topoisomerase I [Moraxella bovoculi].	22.77	470	302	13	187	629	209	644	5e-11	76.6
tr:I3JP28_ORENI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.45	499	285	19	188	634	238	691	5e-11	76.6
rs:WP_021776257	glutamyl-tRNA amidotransferase subunit A Glu-ADT subunit A protein [alpha proteobacterium RS24].	22.97	553	343	20	1	520	1	503	5e-11	76.6
tr:A0A0E0K969_ORYPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OPUNC03G04550.2};	23.57	437	278	17	3	396	15	438	5e-11	76.6
rs:WP_046966935	DNA topoisomerase I [Luteibacter rhizovicinus].	24.75	408	246	13	163	536	142	522	5e-11	76.6
rs:WP_011293207	DNA topoisomerase I [Thermobifida fusca].	23.29	601	325	23	2	530	22	558	5e-11	76.6
gpu:CP009520_2425	DNA topoisomerase I [Methanosarcina vacuolata Z-761]	22.77	650	388	25	90	670	92	696	5e-11	76.6
rs:XP_005098681	PREDICTED: DNA topoisomerase 3-alpha-like [Aplysia californica].	23.74	657	376	27	46	634	79	678	5e-11	77.0
rs:WP_027585179	DNA topoisomerase I [Prolixibacter bellariivorans].	23.83	596	367	19	3	578	5	533	5e-11	76.6
rs:WP_013760650	DNA topoisomerase I [Porphyromonas asaccharolytica].	22.72	537	334	18	3	520	7	481	5e-11	76.6
rs:WP_006100088	DNA topoisomerase I [Coleofasciculus chthonoplastes].	23.11	528	315	16	96	572	86	573	5e-11	76.6
rs:WP_015739396	topoisomerase [Ammonifex degensii].	24.09	523	312	17	82	584	681	1138	5e-11	76.6
rs:WP_026303996	DNA topoisomerase I [Kaistia granuli].	22.97	688	416	27	1	630	1	632	5e-11	76.6
tr:L1MQG7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	25.55	411	244	18	251	634	32	407	5e-11	75.9
tr:K2CUE4_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	23.54	480	293	16	3	445	5	447	5e-11	75.9
rs:WP_013048901	DNA topoisomerase I [Aminobacterium colombiense].	24.05	607	365	25	83	636	65	628	5e-11	76.6
rs:WP_040843384	DNA topoisomerase I [Nitrospirillum amazonense].	21.75	639	403	20	55	629	30	635	5e-11	76.6
rs:WP_041958543	DNA topoisomerase I [Sulfurospirillum arsenophilum].	22.58	651	390	22	3	614	4	579	5e-11	76.3
rs:WP_025064689	hypothetical protein, partial [Prevotella disiens].	33.57	143	77	5	4	135	5	140	5e-11	72.4
tr:F4X1K5_ACREC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.48	461	303	12	188	619	157	587	5e-11	76.6
rs:WP_031491537	DNA topoisomerase I [Succinivibrio dextrinosolvens].	22.56	563	371	18	74	612	78	599	5e-11	76.6
rs:XP_009137998	PREDICTED: uncharacterized protein LOC103862037 isoform X2 [Brassica rapa].	23.46	648	396	30	32	618	379	987	5e-11	76.6
tr:M4E5G3_BRARP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.46	648	396	30	32	618	382	990	5e-11	76.6
rs:WP_013320268	DNA topoisomerase I [Cyanothece sp. PCC 7822].	23.53	527	306	16	100	572	90	573	5e-11	76.6
rs:WP_039620968	DNA topoisomerase I [Acinetobacter harbinensis].	23.53	476	292	15	187	629	211	647	5e-11	76.6
rs:WP_036432809	DNA topoisomerase I [Mycoplasma hominis].	23.83	596	362	23	73	629	50	592	5e-11	76.3
rs:WP_022488349	DNA topoisomerase [Acidaminococcus sp. CAG:542].	23.43	559	357	20	90	616	67	586	5e-11	76.3
rs:WP_011933781	DNA topoisomerase I [Synechococcus sp. WH 7803].	21.61	620	386	19	3	572	5	574	5e-11	76.6
rs:WP_004649883	DNA topoisomerase I [Acinetobacter bohemicus].	23.81	483	282	16	187	629	211	647	5e-11	76.6
rs:XP_008807899	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Phoenix dactylifera].	21.01	633	410	22	3	585	13	605	5e-11	76.6
rs:WP_015144218	DNA topoisomerase I [Pleurocapsa minor].	22.66	587	333	20	3	530	4	528	5e-11	76.6
rs:XP_008807898	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Phoenix dactylifera].	21.01	633	410	22	3	585	13	605	5e-11	76.6
rs:WP_005938434	DNA topoisomerase I [Gordonia hirsuta].	24.07	594	329	24	2	530	13	549	5e-11	76.6
rs:WP_000277574	DNA topoisomerase I [Helicobacter pylori].	23.13	467	308	12	99	537	77	520	5e-11	76.3
rs:WP_001951669	DNA topoisomerase [Helicobacter pylori].	23.29	468	307	13	99	537	77	521	5e-11	76.3
sp:RGYR1_AQUAE	RecName: Full=Reverse gyrase 1 {ECO:0000255|HAMAP-Rule:MF_01125}; Includes: RecName: Full=Helicase {ECO:0000255|HAMAP-Rule:MF_01125}; EC=3.6.4.12 {ECO:0000255|HAMAP-Rule:MF_01125}; Includes: RecName: Full=Topoisomerase {ECO:0000255|HAMAP-Rule:MF_01125}; EC=5.99.1.3 {ECO:0000255|HAMAP-Rule:MF_01125};	22.66	556	319	20	77	600	669	1145	5e-11	76.6
rs:WP_034053622	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	30.77	156	99	2	457	611	70	217	5e-11	73.2
tr:T5D5T9_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	23.99	546	347	18	80	583	128	647	5e-11	76.3
rs:WP_036489275	DNA topoisomerase I, partial [Myxosarcina sp. GI1].	24.38	480	310	13	76	536	57	502	5e-11	76.3
rs:WP_011294401	DNA topoisomerase I [Prochlorococcus marinus].	23.64	571	325	22	3	519	7	520	5e-11	76.6
rs:XP_012581982	PREDICTED: DNA topoisomerase 3-alpha [Condylura cristata].	22.58	496	291	17	188	634	239	690	5e-11	76.6
rs:WP_000179634	hypothetical protein, partial [Streptococcus pneumoniae].	26.78	295	190	9	87	365	75	359	5e-11	74.7
rs:WP_004138408	DNA topoisomerase I [Gardnerella vaginalis].	23.44	627	368	23	2	571	6	577	5e-11	76.6
rs:WP_008245900	DNA topoisomerase I [Sulfurovum sp. AR].	25.42	413	252	14	3	392	4	383	5e-11	76.3
rs:WP_035266776	DNA topoisomerase I [Acinetobacter sp. Ver3].	23.80	479	287	17	187	629	211	647	5e-11	76.6
rs:WP_025084927	DNA topoisomerase I [Lactobacillus paralimentarius].	22.83	587	372	23	90	635	70	616	5e-11	76.3
tr:W4W354_ATTCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.50	479	317	12	188	634	207	658	5e-11	76.6
rs:XP_001272941	DNA topoisomerase III, putative [Aspergillus clavatus NRRL 1].	22.64	636	404	21	3	584	7	608	6e-11	76.3
rs:WP_013306390	DNA topoisomerase I [Maribacter sp. HTCC2170].	27.23	382	227	12	157	521	132	479	6e-11	76.3
rs:WP_039061692	DNA topoisomerase III, partial [Shigella flexneri].	29.20	226	150	5	265	481	2	226	6e-11	73.6
rs:WP_003797809	DNA topoisomerase I [Arthrobacter globiformis].	22.78	575	354	21	2	530	10	540	6e-11	76.6
rs:WP_014561621	DNA topoisomerase I [Ignavibacterium album].	23.13	601	370	21	3	580	5	536	6e-11	76.3
tr:J9J1U5_9SPIT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.27	361	232	8	252	598	393	722	6e-11	76.6
rs:XP_004481477	PREDICTED: DNA topoisomerase 3-alpha [Dasypus novemcinctus].	22.31	484	307	18	188	634	239	690	6e-11	76.6
tr:A0A0C6FHI5_PSEAI	SubName: Full=Pseudomonas aeruginosa DNA, complete genome, strain: NCGM257 {ECO:0000313|EMBL:BAQ42215.1}; EC=5.99.1.2 {ECO:0000313|EMBL:BAQ42215.1};	23.02	517	281	19	74	537	11	463	6e-11	75.9
rs:WP_040848521	DNA topoisomerase I, partial [Thiothrix flexilis].	23.89	519	328	18	55	534	29	519	6e-11	76.3
rs:XP_012057921	PREDICTED: DNA topoisomerase 3-alpha-like [Atta cephalotes].	21.50	479	317	12	188	634	253	704	6e-11	76.6
rs:WP_027276830	DNA topoisomerase I [Rhodopseudomonas palustris].	23.21	698	403	33	1	630	1	633	6e-11	76.6
rs:WP_011403873	DNA topoisomerase I [Salinibacter ruber].	22.32	596	343	20	2	530	3	545	6e-11	76.3
rs:WP_022816092	DNA topoisomerase I [Poribacteria bacterium WGA-3G].	22.74	585	381	20	89	629	63	620	6e-11	76.3
rs:WP_006795971	DNA topoisomerase I [Flavobacteria bacterium BBFL7].	24.81	661	414	25	3	627	5	618	6e-11	76.3
rs:XP_004684597	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Condylura cristata].	22.58	496	291	17	188	634	239	690	6e-11	76.6
rs:WP_036579925	DNA topoisomerase I [Nonlabens ulvanivorans].	25.15	664	408	28	3	627	5	618	6e-11	76.3
tr:A0A090BFX1_KLUMA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.74	409	257	13	188	560	229	614	6e-11	76.3
gpu:CP009501_74	DNA topoisomerase I [Methanosarcina thermophila TM-1]	22.40	674	425	26	46	670	52	676	6e-11	76.3
tr:A0A067Q4C2_9HOMO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.17	627	395	21	3	577	4	589	6e-11	76.3
rs:WP_037984289	DNA topoisomerase I [Tannerella sp. oral taxon BU063].	25.14	537	324	19	3	520	5	482	6e-11	76.3
rs:WP_008154288	MULTISPECIES: DNA topoisomerase I [Parabacteroides].	22.39	536	337	15	3	520	5	479	6e-11	76.3
rs:WP_037348525	DNA topoisomerase I [Selenomonas sp. F0473].	21.64	670	428	23	3	636	33	641	6e-11	76.3
rs:WP_002348935	DNA topoisomerase, partial [Enterococcus faecium].	32.18	174	100	4	158	317	23	192	6e-11	72.8
tr:A0A0E0NQ40_ORYRU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ORUFI03G04550.4};	23.37	445	269	18	3	396	13	436	6e-11	76.3
rs:WP_010844242	DNA topoisomerase I subunit omega [Gordonia terrae].	24.28	589	336	22	2	530	16	554	6e-11	76.3
rs:XP_009156664	DNA topoisomerase III [Exophiala dermatitidis NIH/UT8656].	22.05	644	394	24	3	584	7	604	6e-11	75.9
rs:WP_020018887	hypothetical protein [actinobacterium SCGC AAA015-D07].	26.36	349	190	16	3	314	5	323	6e-11	76.3
rs:WP_023132186	DNA topoisomerase I [Pseudomonas aeruginosa].	23.12	519	278	19	74	537	59	511	6e-11	75.9
rs:WP_045574983	DNA topoisomerase I [Desulfosporosinus sp. I2].	22.82	631	391	26	90	675	67	646	6e-11	76.3
rs:WP_000277559	DNA topoisomerase I [Helicobacter pylori].	23.85	478	292	15	99	537	77	521	6e-11	75.9
rs:WP_042923545	DNA topoisomerase I [Kingella kingae].	21.44	681	422	23	70	679	37	675	6e-11	76.3
rs:WP_038312059	DNA topoisomerase I [Kingella kingae].	21.35	665	420	22	76	679	53	675	6e-11	76.3
rs:XP_002785799	DNA topoisomerase 3-beta-1, putative [Perkinsus marinus ATCC 50983].	21.55	608	388	20	3	566	6	568	6e-11	76.3
tr:M4C198_HYAAE	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblProtists:HpaP812836};	23.96	384	246	10	188	551	225	582	6e-11	75.9
rs:WP_044413633	DNA topoisomerase I [Thioalkalimicrobium microaerophilum].	22.77	593	374	18	3	578	4	529	6e-11	76.3
rs:WP_004113830	DNA topoisomerase I [Gardnerella vaginalis].	23.70	637	354	24	2	571	6	577	6e-11	76.3
tr:K6XNM9_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.13	557	324	22	32	530	14	535	6e-11	76.3
rs:WP_022587101	reverse gyrase [Caldanaerobacter subterraneus].	24.05	578	328	24	2	536	554	1063	6e-11	76.3
rs:WP_001066142	DNA topoisomerase I [Helicobacter pylori].	24.14	522	331	17	103	583	73	570	6e-11	75.9
rs:WP_036258305	DNA topoisomerase I [Methylocapsa aurea].	23.34	724	424	30	1	661	1	656	6e-11	76.3
rs:WP_013678931	DNA topoisomerase [Thermoproteus uzoniensis].	21.42	537	348	19	85	588	86	581	6e-11	75.9
rs:WP_015772462	DNA topoisomerase I [Jonesia denitrificans].	21.85	595	359	19	2	538	6	552	6e-11	76.3
rs:WP_010880728	reverse gyrase [Aquifex aeolicus].	23.66	634	345	25	3	576	607	1161	7e-11	76.3
tr:K6JEI1_KLEOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKP25391.1};	33.78	148	88	3	486	632	8	146	7e-11	72.0
rs:WP_009745737	DNA topoisomerase I [Capnocytophaga sp. oral taxon 338].	24.29	531	332	18	3	521	5	477	7e-11	76.3
tr:W1PGM2_AMBTC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.82	424	280	17	3	396	6	416	7e-11	75.5
tr:X1PTH7_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S12043 {ECO:0000313|EMBL:GAI42405.1}; Flags: Fragment;	25.66	304	161	11	263	544	1	261	7e-11	73.2
rs:XP_007910121	PREDICTED: DNA topoisomerase 3-alpha [Callorhinchus milii].	21.99	473	287	18	188	619	229	660	7e-11	76.3
rs:WP_043215225	DNA topoisomerase I [Pseudomonas putida].	22.85	582	370	15	84	638	69	598	7e-11	75.9
rs:WP_038676167	DNA topoisomerase I [Pimelobacter simplex].	22.66	662	386	25	2	591	4	611	7e-11	76.3
rs:XP_007737879	DNA topoisomerase III [Capronia epimyces CBS 606.96].	22.19	640	398	24	3	584	7	604	7e-11	75.9
gpu:AP013044_1404	DNA topoisomerase I [Tannerella forsythia 3313]	23.62	542	327	18	2	520	4	481	7e-11	76.3
rs:WP_022436798	DNA topoisomerase [Prevotella sp. CAG:279].	22.61	544	337	19	3	526	42	521	7e-11	76.3
tr:L7JG16_MAGOP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.27	550	371	15	3	519	5	525	7e-11	75.9
rs:WP_034019142	hypothetical protein, partial [Pseudomonas aeruginosa].	23.19	483	294	19	163	619	138	569	7e-11	75.9
rs:XP_010546322	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Tarenaya hassleriana].	21.01	633	409	22	3	585	12	603	7e-11	76.3
rs:XP_011696307	PREDICTED: DNA topoisomerase 3-alpha-like isoform X1 [Wasmannia auropunctata].	22.51	462	295	16	188	619	248	676	7e-11	76.3
rs:WP_028901307	hypothetical protein, partial [Prevotella timonensis].	34.96	123	63	4	4	115	5	121	7e-11	71.2
rs:WP_033244489	MULTISPECIES: DNA topoisomerase I, partial [Actinomycetales].	22.76	602	330	23	2	530	17	556	7e-11	76.3
rs:WP_021833112	DNA topoisomerase I [Crocosphaera watsonii].	23.80	521	308	16	90	560	5	486	7e-11	76.3
tr:K2H0F1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.62	650	381	27	77	659	53	660	7e-11	75.9
rs:WP_037978261	DNA topoisomerase I [Tannerella sp. oral taxon BU063].	25.19	536	325	20	3	520	5	482	7e-11	75.9
rs:WP_017298517	hypothetical protein [Nodosilinea nodulosa].	23.04	612	373	20	3	565	4	566	7e-11	76.3
rs:XP_010546323	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Tarenaya hassleriana].	21.01	633	409	22	3	585	12	603	7e-11	76.3
rs:WP_023110980	DNA topoisomerase I [Pseudomonas aeruginosa].	23.31	519	277	19	74	537	59	511	7e-11	75.9
tr:A0A094DBX6_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY63936.1};	21.93	570	365	20	3	532	6	535	7e-11	75.9
rs:WP_032806483	topoisomerase I, partial [Oenococcus oeni].	25.37	205	131	5	297	489	1	195	7e-11	72.8
rs:XP_008667766	PREDICTED: hypothetical protein isoform X4 [Zea mays].	22.30	426	262	14	188	585	121	505	7e-11	75.9
rs:WP_007746465	DNA topoisomerase I [Oenococcus kitaharae].	23.19	483	305	16	163	616	144	589	7e-11	75.9
rs:WP_004123146	DNA topoisomerase I [Gardnerella vaginalis].	23.70	637	354	24	2	571	6	577	7e-11	76.3
rs:XP_007060121	PREDICTED: DNA topoisomerase 3-alpha [Chelonia mydas].	23.87	465	288	15	188	619	241	672	7e-11	76.3
rs:WP_017193621	hypothetical protein [Vaccinium witches'-broom phytoplasma].	23.08	559	361	16	100	633	79	593	7e-11	75.9
rs:WP_042510470	DNA topoisomerase I [Moraxella catarrhalis].	23.09	485	282	17	187	629	207	642	7e-11	76.3
rs:WP_007317029	DNA topoisomerase I [Gordonia effusa].	24.41	594	332	25	2	530	15	556	7e-11	76.3
rs:WP_019144471	DNA topoisomerase I [Aeromicrobium massiliense].	24.90	502	292	19	77	528	67	533	7e-11	76.3
rs:XP_004684598	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Condylura cristata].	22.58	496	291	17	188	634	144	595	7e-11	76.3
rs:WP_020002660	DNA topoisomerase I [Mycoplasma hominis].	23.83	596	362	23	73	629	50	592	7e-11	75.9
tr:D4KE79_9FIRM	SubName: Full=Draft genome {ECO:0000313|EMBL:CBL06676.1};	28.89	180	112	3	457	629	99	269	7e-11	73.6
rs:XP_003713792	DNA topoisomerase III [Magnaporthe oryzae 70-15].	21.27	550	371	15	3	519	5	525	7e-11	75.9
rs:WP_019261354	DNA topoisomerase I [Gardnerella vaginalis].	23.91	644	344	25	2	571	6	577	7e-11	76.3
sp:RGYR2_AQUAE	RecName: Full=Reverse gyrase 2 {ECO:0000255|HAMAP-Rule:MF_01125}; Includes: RecName: Full=Helicase {ECO:0000255|HAMAP-Rule:MF_01125}; EC=3.6.4.12 {ECO:0000255|HAMAP-Rule:MF_01125}; Includes: RecName: Full=Topoisomerase {ECO:0000255|HAMAP-Rule:MF_01125}; EC=5.99.1.3 {ECO:0000255|HAMAP-Rule:MF_01125};	23.66	634	345	25	3	576	589	1143	7e-11	76.3
tr:J3E777_9VIRU	SubName: Full=Topoisomerase I (Bacterial type) {ECO:0000313|EMBL:EJN40679.1};	24.37	476	286	20	90	521	64	509	7e-11	75.9
rs:WP_034056250	DNA topoisomerase I [Pseudomonas aeruginosa].	21.54	599	371	20	74	633	85	623	7e-11	75.9
rs:WP_002639752	DNA topoisomerase I [Myxococcus sp. (contaminant ex DSM 436)].	22.76	624	386	27	76	640	130	716	7e-11	75.9
rs:WP_036845096	MULTISPECIES: DNA topoisomerase I [Porphyromonas].	23.02	643	384	22	3	617	5	564	7e-11	75.9
rs:WP_020280286	DNA topoisomerase I [Lactobacillus otakiensis].	22.68	560	362	21	103	629	101	622	7e-11	75.9
rs:WP_033624172	hypothetical protein, partial [Enterococcus faecium].	39.02	123	71	1	103	221	3	125	7e-11	71.2
rs:WP_043464656	DNA topoisomerase I [Streptomyces fradiae].	22.50	591	342	21	2	530	13	549	8e-11	76.3
gpu:KM982402_222	topoisomerase I [Acanthamoeba polyphaga mimivirus]	24.69	478	282	20	90	521	64	509	8e-11	75.9
rs:WP_007339188	DNA topoisomerase I [Rhodopirellula baltica].	22.32	596	326	19	3	530	33	559	8e-11	76.3
rs:WP_007334156	DNA topoisomerase I [Rhodopirellula baltica].	22.32	596	326	19	3	530	33	559	8e-11	76.3
rs:WP_040532974	DNA topoisomerase I [Lactobacillus pobuzihii].	22.55	581	363	21	90	629	60	594	8e-11	75.9
rs:XP_007048481	Topoisomerase 3alpha isoform 2, partial [Theobroma cacao].	22.30	417	273	13	188	585	215	599	8e-11	75.9
rs:WP_036438960	DNA topoisomerase I [Mycoplasma hominis].	23.83	596	362	23	73	629	50	592	8e-11	75.5
rs:XP_004575543	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Maylandia zebra].	22.89	498	289	19	188	634	176	629	8e-11	75.9
rs:WP_010114390	topoisomerase I [Acinetobacter sp. P8-3-8].	24.55	387	213	13	187	541	213	552	8e-11	75.9
tr:A0A078B952_STYLE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.69	454	292	16	154	585	641	1057	8e-11	76.3
rs:WP_035237944	DNA topoisomerase, partial [Acidobacteriaceae bacterium URHE0068].	24.50	600	356	21	79	616	57	621	8e-11	75.9
rs:WP_038318343	DNA topoisomerase I [Kingella kingae].	21.44	681	422	23	70	679	37	675	8e-11	75.9
rs:WP_028901305	hypothetical protein, partial [Prevotella timonensis].	34.96	123	63	4	4	115	5	121	8e-11	71.2
rs:WP_033504057	DNA topoisomerase I, partial [Bifidobacterium actinocoloniiforme].	22.81	627	384	20	2	571	6	589	8e-11	75.9
tr:H2NSY8_PONAB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.06	485	307	16	188	634	235	686	8e-11	75.9
tr:K2A4U6_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.55	682	420	21	1	629	1	620	8e-11	75.9
rs:WP_003663911	topoisomerase I [Moraxella catarrhalis].	23.09	485	282	17	187	629	207	642	8e-11	75.9
rs:WP_013056625	hypothetical protein [Bacillus megaterium].	37.29	118	56	5	1	107	1	111	8e-11	70.9
tr:F3J5T6_PSEAP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGH79762.1}; Flags: Fragment;	25.50	200	144	4	398	592	6	205	8e-11	72.8
rs:WP_019598710	DNA topoisomerase I [Rhodonellum psychrophilum].	23.29	541	326	19	3	520	5	479	8e-11	75.9
tr:F3FHN5_PSESX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	23.78	429	274	13	226	633	9	405	8e-11	75.5
rs:WP_020260876	hypothetical protein [Candidatus Aminicenans sakinawicola].	23.25	572	369	19	90	629	67	600	8e-11	75.9
tr:U6DA30_NEOVI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	21.88	480	314	15	188	634	209	660	8e-11	75.9
rs:WP_037559452	DNA topoisomerase I [Spirillospora albida].	23.06	607	316	25	2	530	19	552	8e-11	75.9
rs:WP_025073208	hypothetical protein, partial [Prevotella timonensis].	34.96	123	63	4	4	115	5	121	8e-11	70.9
rs:WP_036906785	DNA topoisomerase I [Prochlorococcus marinus].	23.67	566	331	21	3	519	7	520	8e-11	75.9
rs:WP_039749312	DNA topoisomerase I [Hassallia byssoidea].	26.79	321	218	8	77	392	54	362	8e-11	75.9
tr:A0A0E1QH36_CLOBO	SubName: Full=Putative DNA topoisomerase I {ECO:0000313|EMBL:BAQ14121.1};	26.47	578	332	26	83	616	64	592	8e-11	75.9
rs:XP_004312664	PREDICTED: DNA topoisomerase 3-alpha [Tursiops truncatus].	23.28	494	290	18	188	634	239	690	8e-11	75.9
tr:W0WM01_PSEAI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CDH72766.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDH72766.1};	30.36	168	104	4	467	629	3	162	8e-11	72.0
tr:B9KIC6_ANAMF	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.00	700	395	29	1	629	2	628	8e-11	75.9
tr:F3R6F7_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	23.39	466	287	19	200	629	1	432	8e-11	75.1
rs:XP_011696308	PREDICTED: DNA topoisomerase 3-alpha-like isoform X2 [Wasmannia auropunctata].	22.51	462	295	16	188	619	157	585	8e-11	75.9
rs:WP_003657116	topoisomerase I [Moraxella catarrhalis].	23.09	485	282	17	187	629	207	642	8e-11	75.9
rs:XP_004575542	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Maylandia zebra].	22.89	498	289	19	188	634	256	709	9e-11	75.9
rs:XP_009266901	DNA topoisomerase 3 [Wallemia ichthyophaga EXF-994].	22.26	647	373	28	3	577	6	594	9e-11	75.9
rs:WP_010264176	DNA topoisomerase I [Anaplasma marginale].	23.00	700	395	29	1	629	1	627	9e-11	75.9
rs:WP_028638708	DNA topoisomerase I [Nocardioides sp. URHA0032].	22.53	657	393	26	2	591	4	611	9e-11	75.9
rs:WP_032808023	topoisomerase I, partial [Oenococcus oeni].	30.47	128	87	1	467	592	2	129	9e-11	72.4
rs:WP_014289717	topoisomerase [Pyrobaculum sp. 1860].	22.91	454	272	16	157	584	828	1229	9e-11	75.9
rs:WP_010325857	topoisomerase I [Acinetobacter lwoffii].	22.74	475	297	14	187	629	212	648	9e-11	75.9
rs:WP_038316816	DNA topoisomerase I [Kingella kingae].	21.44	681	422	23	70	679	37	675	9e-11	75.9
rs:WP_034354030	TopA [Helicobacter sp. MIT 09-6949].	23.00	513	324	17	103	575	71	552	9e-11	75.5
rs:WP_016459086	DNA topoisomerase I [Corynebacterium pyruviciproducens].	25.37	473	277	14	103	530	94	535	9e-11	75.9
rs:WP_023386700	DNA topoisomerase I [Anaplasma marginale].	23.00	700	395	29	1	629	1	627	9e-11	75.9
rs:XP_004202179	Piso0_001663 [Millerozyma farinosa CBS 7064].	22.68	626	385	23	3	574	4	584	9e-11	75.5
sp:RGYR_CALS4	RecName: Full=Reverse gyrase {ECO:0000255|HAMAP-Rule:MF_01125}; Includes: RecName: Full=Helicase {ECO:0000255|HAMAP-Rule:MF_01125}; EC=3.6.4.12 {ECO:0000255|HAMAP-Rule:MF_01125}; Includes: RecName: Full=Topoisomerase {ECO:0000255|HAMAP-Rule:MF_01125}; EC=5.99.1.3 {ECO:0000255|HAMAP-Rule:MF_01125};	23.92	577	330	23	2	536	556	1065	9e-11	75.9
rs:WP_003141417	DNA topoisomerase I [Pseudomonas aeruginosa].	22.87	516	285	19	74	537	59	513	9e-11	75.5
rs:XP_011167166	PREDICTED: DNA topoisomerase 3-alpha [Solenopsis invicta].	24.72	542	344	21	46	560	104	608	9e-11	75.9
rs:WP_041587177	reverse gyrase [Caldanaerobacter subterraneus].	23.92	577	330	23	2	536	554	1063	9e-11	75.9
tr:I3QGN7_9FLAO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	27.64	492	282	22	91	548	5	456	9e-11	75.5
rs:WP_007454679	DNA topoisomerase I [Micromonospora lupini].	23.32	639	364	28	2	571	9	590	9e-11	75.9
rs:WP_014026509	reverse gyrase [Pyrolobus fumarii].	22.56	492	297	17	81	544	730	1165	9e-11	75.9
rs:WP_014697157	DNA topoisomerase I [Bifidobacterium animalis].	22.64	583	349	22	2	530	6	540	9e-11	75.9
rs:WP_009197744	DNA topoisomerase I [Actinomyces sp. oral taxon 848].	23.91	598	324	24	2	530	3	538	9e-11	75.9
rs:WP_014224989	DNA topoisomerase I [Tannerella forsythia].	23.48	541	329	18	2	520	4	481	9e-11	75.9
rs:WP_022858104	DNA topoisomerase I [Bifidobacterium pseudolongum].	21.31	624	390	20	2	571	6	582	9e-11	75.9
tr:I3MP50_SPETR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.05	486	301	17	188	634	239	690	9e-11	75.9
rs:WP_019174490	DNA topoisomerase I [Brevibacterium massiliense].	23.73	628	351	25	4	553	1	578	9e-11	75.9
rs:XP_005339523	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Ictidomys tridecemlineatus].	23.05	486	301	17	188	634	239	690	9e-11	75.9
rs:WP_014659216	DNA topoisomerase I [Helicobacter cetorum].	23.20	707	410	29	3	636	4	650	9e-11	75.5
rs:WP_004369289	DNA topoisomerase I [Prevotella oralis].	22.77	606	362	22	3	578	5	534	9e-11	75.5
rs:WP_011823237	DNA topoisomerase I [Prochlorococcus marinus].	23.64	571	325	22	3	519	7	520	9e-11	75.9
rs:WP_012855440	DNA topoisomerase I [Mycoplasma hominis].	23.66	596	363	23	73	629	50	592	9e-11	75.5
rs:WP_036918120	MULTISPECIES: DNA topoisomerase I, partial [Prochlorococcus].	22.26	530	329	15	90	572	81	574	9e-11	75.9
tr:L0NDR6_RHISP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.34	667	398	26	38	630	16	636	9e-11	75.9
rs:WP_044420529	DNA topoisomerase I [Mycoplasma hominis].	23.66	596	363	23	73	629	50	592	9e-11	75.5
rs:WP_006295453	DNA topoisomerase I [Bifidobacterium gallicum].	22.86	630	378	21	2	571	6	587	9e-11	75.9
rs:XP_003142175	DNA topoisomerase III beta-1 [Loa loa].	23.26	430	261	15	188	585	213	605	9e-11	75.9
rs:XP_005339524	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Ictidomys tridecemlineatus].	23.05	486	301	17	188	634	239	690	9e-11	75.9
rs:XP_012603374	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Microcebus murinus].	21.88	480	314	15	188	634	239	690	9e-11	75.9
rs:WP_017707944	hypothetical protein [Pseudomonas syringae].	22.77	382	253	10	163	526	135	492	9e-11	75.5
rs:XP_001265835	DNA topoisomerase III, putative [Neosartorya fischeri NRRL 181].	22.94	545	327	18	79	573	37	538	9e-11	75.1
tr:A0A0E0GH86_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA03G04610.4};	23.37	445	269	18	3	396	14	437	1e-10	75.9
rs:WP_006435073	DNA topoisomerase I [Gordonia amicalis].	24.04	599	336	22	2	530	16	565	1e-10	75.9
rs:WP_001938392	DNA topoisomerase [Helicobacter pylori].	22.91	467	309	12	99	537	77	520	1e-10	75.1
rs:WP_047305771	DNA topoisomerase I [Pseudomonas fluorescens].	24.47	470	304	12	84	533	69	507	1e-10	75.5
rs:XP_012520437	PREDICTED: DNA topoisomerase 3-alpha [Propithecus coquereli].	22.73	484	305	17	188	634	239	690	1e-10	75.9
rs:WP_044069353	DNA topoisomerase I [Pseudomonas aeruginosa].	22.63	517	283	19	74	537	59	511	1e-10	75.5
rs:WP_046323449	DNA topoisomerase I [Bifidobacterium asteroides].	22.24	634	376	24	2	571	6	586	1e-10	75.9
rs:WP_039341893	DNA topoisomerase I [Chryseobacterium solincola].	26.57	399	241	15	3	392	5	360	1e-10	75.5
tr:J6B175_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJX75617.1}; Flags: Fragment;	30.07	143	98	1	413	553	16	158	1e-10	71.6
rs:WP_024933161	DNA topoisomerase I [Clostridium botulinum].	26.47	578	332	26	83	616	60	588	1e-10	75.5
rs:XP_009546939	hypothetical protein HETIRDRAFT_46055 [Heterobasidion irregulare TC 32-1].	21.73	626	419	23	3	584	4	602	1e-10	75.5
rs:WP_001884990	DNA topoisomerase I [Helicobacter pylori].	23.50	468	306	13	99	537	77	521	1e-10	75.5
rs:WP_046871126	DNA topoisomerase I [Pediococcus damnosus].	22.79	566	354	21	103	629	99	620	1e-10	75.5
rs:WP_013061650	DNA topoisomerase I [Salinibacter ruber].	23.01	591	345	19	2	530	3	545	1e-10	75.5
rs:WP_015081448	DNA topoisomerase I [Anabaena sp. 90].	22.04	608	374	19	3	560	4	561	1e-10	75.5
gpu:KM982401_221	topoisomerase I [Acanthamoeba polyphaga mimivirus]	24.37	476	286	20	90	521	64	509	1e-10	75.5
rs:WP_044329464	DNA topoisomerase I [Mycoplasma hominis].	23.66	596	363	23	73	629	50	592	1e-10	75.1
rs:WP_046318093	hypothetical protein [Lactobacillus mellifer].	26.44	208	130	8	8	204	20	215	1e-10	75.5
rs:XP_004266833	PREDICTED: DNA topoisomerase 3-alpha [Orcinus orca].	23.28	494	290	18	188	634	239	690	1e-10	75.9
rs:WP_034086288	DNA topoisomerase I [Pseudomonas aeruginosa].	23.12	519	278	19	74	537	59	511	1e-10	75.5
rs:WP_010219002	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	30.91	165	101	3	470	629	9	165	1e-10	72.0
tr:A0A094QJY2_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KGA14741.1};	23.46	584	340	23	1	530	11	541	1e-10	75.5
tr:A0A0A2BV50_9PROC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.26	530	329	15	90	572	61	554	1e-10	75.5
rs:WP_004331586	DNA topoisomerase I [Porphyromonas asaccharolytica].	22.72	537	334	18	3	520	7	481	1e-10	75.5
rs:WP_031520179	DNA topoisomerase I [Streptomyces sp. NRRL F-5123].	23.33	600	327	23	2	530	13	550	1e-10	75.5
tr:K9J3S6_DESRO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.09	485	296	17	188	631	77	525	1e-10	75.5
rs:WP_004978972	DNA topoisomerase I [Acinetobacter johnsonii].	24.27	375	229	11	187	541	212	551	1e-10	75.5
rs:WP_032602860	DNA topoisomerase I, partial [Bacteroides fragilis].	25.23	214	155	3	374	583	2	214	1e-10	72.4
rs:WP_013155942	DNA topoisomerase I [Nocardiopsis dassonvillei].	22.17	591	342	18	3	530	25	560	1e-10	75.5
tr:E9IAV6_SOLIN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.72	542	344	21	46	560	58	562	1e-10	75.5
rs:WP_038310428	DNA topoisomerase I [Kingella kingae].	21.20	665	421	22	76	679	53	675	1e-10	75.5
rs:XP_004202802	Piso0_001663 [Millerozyma farinosa CBS 7064].	22.28	624	390	22	3	574	4	584	1e-10	75.1
rs:WP_023450209	DNA topoisomerase I [Asticcacaulis sp. AC402].	21.55	631	386	19	1	589	1	564	1e-10	75.5
rs:WP_007618918	DNA topoisomerase I [Gordonia soli].	23.48	592	339	21	2	530	17	557	1e-10	75.5
rs:WP_019610476	DNA topoisomerase I [Nocardiopsis sp. CNS639].	22.17	591	342	18	3	530	25	560	1e-10	75.5
rs:XP_008913563	hypothetical protein PPTG_17637 [Phytophthora parasitica INRA-310].	24.43	614	371	26	1	560	1	575	1e-10	75.5
rs:XP_688695	PREDICTED: DNA topoisomerase 3-alpha [Danio rerio].	22.95	475	287	15	188	622	236	671	1e-10	75.5
rs:WP_038061507	topoisomerase [Thermodesulfobacterium commune].	24.90	482	269	16	82	536	699	1114	1e-10	75.9
rs:WP_020304538	DNA topoisomerase III [Pseudomonas syringae].	29.36	218	126	11	1	204	1	204	1e-10	72.4
rs:WP_004692508	DNA topoisomerase I [Acinetobacter johnsonii].	22.74	475	297	14	187	629	212	648	1e-10	75.5
rs:WP_019002142	hypothetical protein [Succinimonas amylolytica].	23.57	454	281	14	187	616	181	592	1e-10	75.5
rs:WP_046037550	DNA topoisomerase I [Campylobacter fetus].	23.95	522	329	20	100	587	72	559	1e-10	75.1
tr:X5JYV5_9NOST	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.35	431	274	10	187	574	144	552	1e-10	75.5
rs:WP_037224279	DNA topoisomerase I [Richelia intracellularis].	21.35	431	274	10	187	574	173	581	1e-10	75.5
rs:XP_009657191	DNA topoisomerase [Verticillium dahliae VdLs.17].	23.06	555	352	21	3	519	4	521	1e-10	75.5
rs:WP_039089734	DNA topoisomerase I [Helicobacter pylori].	23.50	468	306	12	99	537	77	521	1e-10	75.1
rs:WP_042930287	DNA topoisomerase I [Pseudomonas aeruginosa].	23.12	519	278	19	74	537	59	511	1e-10	75.1
rs:WP_042916887	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	22.87	516	285	19	74	537	59	513	1e-10	75.1
rs:WP_041077912	DNA topoisomerase I [Candidatus Rickettsia asemboensis].	22.29	700	409	28	1	635	1	630	1e-10	75.5
rs:WP_009544062	MULTISPECIES: DNA topoisomerase I [Cyanothece].	22.66	631	366	20	3	572	4	573	1e-10	75.5
rs:XP_003588646	DNA topoisomerase, partial [Medicago truncatula].	27.08	277	174	8	93	345	58	330	1e-10	75.1
rs:WP_035949104	DNA topoisomerase I [Knoellia flava].	23.59	585	340	21	2	530	9	542	1e-10	75.5
tr:K1S5B8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC50674.1}; Flags: Fragment;	28.19	188	116	6	188	363	1	181	1e-10	71.6
rs:WP_005400852	topoisomerase I [Acinetobacter johnsonii].	22.74	475	297	14	187	629	212	648	1e-10	75.5
rs:WP_000618852	hypothetical protein, partial [Staphylococcus aureus].	23.36	411	267	12	240	629	2	385	1e-10	74.7
rs:WP_007066093	DNA topoisomerase I [Fulvimarina pelagi].	21.96	715	422	30	1	643	1	651	1e-10	75.5
rs:WP_003672057	topoisomerase I [Moraxella catarrhalis].	23.09	485	282	17	187	629	207	642	1e-10	75.5
tr:A0A080ZA52_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETO63513.1};	24.43	614	371	26	1	560	1	575	1e-10	75.5
rs:XP_003420711	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Loxodonta africana].	23.22	521	324	20	188	667	239	724	1e-10	75.5
rs:WP_045182440	DNA topoisomerase I [Elizabethkingia sp. BM10].	25.38	398	247	14	3	392	5	360	1e-10	75.5
tr:G3SN49_LOXAF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.94	523	325	19	188	667	239	726	1e-10	75.5
rs:WP_023408495	hypothetical protein [uncultured Desulfofustis sp. PB-SRB1].	27.88	165	111	3	427	587	1	161	1e-10	72.8
rs:WP_020834237	DNA topoisomerase I [Spiroplasma taiwanense].	23.25	585	352	19	2	543	3	533	1e-10	75.1
rs:XP_006596164	PREDICTED: uncharacterized protein LOC100778913 [Glycine max].	21.78	606	386	22	64	610	310	886	1e-10	75.5
rs:WP_017192448	hypothetical protein [Milkweed yellows phytoplasma].	23.24	568	365	19	70	615	53	571	1e-10	75.1
tr:A0A068EXT8_9LEPT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	24.83	596	354	21	79	629	63	609	1e-10	75.1
rs:WP_041501630	DNA topoisomerase I [Lactobacillus heilongjiangensis].	23.91	594	357	26	90	635	71	617	1e-10	75.1
rs:WP_046833028	hypothetical protein [Xanthomonas axonopodis].	23.30	455	303	13	103	538	78	505	1e-10	75.1
rs:WP_011643221	DNA topoisomerase I [Maricaulis maris].	21.01	714	443	29	1	659	1	648	1e-10	75.5
rs:WP_045821525	DNA topoisomerase I [Williamsia sp. ARP1].	23.78	593	332	23	2	530	17	553	1e-10	75.5
rs:XP_006213913	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha [Vicugna pacos].	23.63	491	292	18	188	634	210	661	1e-10	75.5
rs:WP_012386322	DNA topoisomerase I [Beijerinckia indica].	23.50	685	414	25	1	629	1	631	1e-10	75.5
rs:WP_013553114	DNA topoisomerase I [Nitratifractor salsuginis].	22.36	662	414	20	3	630	4	599	1e-10	75.1
rs:WP_033974776	DNA topoisomerase I [Pseudomonas aeruginosa].	21.91	598	319	22	1	537	1	511	1e-10	75.1
tr:W2YDN6_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETP32748.1};	24.43	614	371	26	1	560	1	575	1e-10	75.5
tr:A0A0B7JSA1_BIOOC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CEO45391.1};	23.10	567	339	23	3	520	4	522	1e-10	75.1
rs:WP_003658699	topoisomerase I [Moraxella catarrhalis].	23.09	485	282	17	187	629	207	642	1e-10	75.5
rs:WP_031459792	DNA topoisomerase I [Chloroflexus sp. MS-G].	23.18	578	363	18	83	612	58	602	1e-10	75.1
rs:WP_034375651	DNA topoisomerase I [Helicobacter suis].	24.22	545	346	19	80	583	52	570	1e-10	75.1
rs:WP_023082041	DNA topoisomerase I [Pseudomonas aeruginosa].	23.12	519	278	19	74	537	59	511	1e-10	75.1
rs:WP_007328430	DNA topoisomerase I [Rhodopirellula baltica].	22.32	596	326	19	3	530	33	559	1e-10	75.5
rs:XP_010548523	PREDICTED: uncharacterized protein LOC104819919 [Tarenaya hassleriana].	22.40	634	404	26	32	610	336	936	1e-10	75.5
rs:WP_034869972	DNA topoisomerase I [Elizabethkingia miricola].	25.38	398	247	14	3	392	5	360	1e-10	75.1
rs:WP_012185865	reverse gyrase [Caldivirga maquilingensis].	22.16	501	312	12	64	536	747	1197	1e-10	75.5
rs:WP_004424930	DNA topoisomerase I [Mycoplasma auris].	23.95	597	361	22	73	630	50	592	1e-10	75.1
rs:WP_045662395	DNA topoisomerase I [Rhodospirillaceae bacterium BRH_c57].	21.93	643	405	25	55	630	27	639	1e-10	75.5
tr:A0A060T6F5_BLAAD	SubName: Full=ARAD1B11726p {ECO:0000313|EMBL:CDP36384.1};	21.65	642	397	24	3	585	4	598	1e-10	75.1
rs:XP_004640343	PREDICTED: DNA topoisomerase 3-alpha [Octodon degus].	22.50	480	301	16	188	629	243	689	1e-10	75.5
rs:WP_024773264	DNA topoisomerase I [Helicobacter pylori].	23.85	545	348	18	80	583	52	570	1e-10	75.1
gpu:AP013045_1345	DNA topoisomerase I [Tannerella forsythia KS16]	23.78	534	336	17	2	520	4	481	1e-10	75.1
rs:XP_567296	DNA topoisomerase type I [Cryptococcus neoformans var. neoformans JEC21].	21.93	652	401	24	3	599	4	602	1e-10	75.1
rs:XP_007080858	PREDICTED: DNA topoisomerase 3-alpha [Panthera tigris altaica].	22.66	481	309	15	188	634	239	690	1e-10	75.1
rs:WP_000277577	DNA topoisomerase I [Helicobacter pylori].	22.91	467	309	12	99	537	77	520	1e-10	75.1
rs:WP_013103076	MULTISPECIES: DNA topoisomerase I [Leuconostoc].	21.88	576	374	18	90	629	90	625	1e-10	75.1
tr:A0A0D9YS70_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OGLUM02G16580.1};	22.59	633	372	27	39	610	309	884	1e-10	75.5
rs:WP_009481330	DNA topoisomerase I [Mobilicoccus pelagius].	22.73	629	381	22	2	571	8	590	1e-10	75.1
rs:WP_031209782	DNA topoisomerase I [Helicobacter pylori].	23.99	546	347	18	80	583	52	571	1e-10	75.1
rs:WP_036863604	DNA topoisomerase I [Porphyromonas sp. COT-108 OH2963].	23.02	643	384	22	3	617	5	564	1e-10	75.1
rs:XP_012603372	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Microcebus murinus].	22.52	484	306	16	188	634	239	690	1e-10	75.5
rs:WP_012832491	DNA topoisomerase I [Gordonia bronchialis].	24.40	586	337	22	2	530	17	553	1e-10	75.5
rs:WP_031285200	DNA topoisomerase I [Pseudomonas aeruginosa].	22.63	517	283	19	74	537	59	511	1e-10	75.1
rs:WP_029678237	DNA topoisomerase I [Bifidobacterium sp. 7101].	23.16	626	378	23	2	571	6	584	1e-10	75.1
rs:WP_027875508	DNA topoisomerase I [Mesoplasma chauliocola].	22.89	616	370	23	61	625	48	609	1e-10	75.1
rs:WP_017740381	DNA topoisomerase I [Scytonema hofmanni].	21.85	604	384	16	3	560	4	565	1e-10	75.1
rs:XP_010025763	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Eucalyptus grandis].	22.73	462	289	16	188	628	218	632	1e-10	75.1
tr:F1R242_DANRE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.95	475	287	15	188	622	236	671	1e-10	75.1
rs:XP_010025764	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Eucalyptus grandis].	22.73	462	289	16	188	628	218	632	1e-10	75.1
rs:WP_038335130	DNA topoisomerase I [Kingella kingae].	21.20	665	421	22	76	679	53	675	1e-10	75.1
rs:WP_020598650	DNA topoisomerase I [Spirosoma panaciterrae].	24.81	403	247	13	3	392	5	364	1e-10	75.1
tr:U6E398_9MOLU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.51	533	339	17	76	581	56	541	1e-10	74.7
rs:WP_023161606	Topoisomerase IA, partial [Candidatus Phytoplasma solani].	22.51	533	339	17	76	581	56	541	1e-10	74.7
tr:B8BDG8_ORYSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.01	465	286	16	3	418	13	454	1e-10	75.1
tr:A0A0B8REZ8_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.56	634	399	25	55	629	28	628	1e-10	75.1
tr:A0A0A2J5C9_PENEN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.16	625	359	26	3	560	6	582	1e-10	74.7
rs:XP_006175691	PREDICTED: DNA topoisomerase 3-alpha [Camelus ferus].	23.42	491	293	18	188	634	181	632	1e-10	75.1
rs:WP_008699413	hypothetical protein [Fusobacterium ulcerans].	37.61	117	58	6	1	110	1	109	1e-10	70.1
rs:WP_025346247	DNA topoisomerase I [Sulfurospirillum multivorans].	22.43	651	391	22	3	614	4	579	1e-10	75.1
rs:XP_001658595	AAEL007683-PA [Aedes aegypti].	25.36	481	270	22	185	619	226	663	1e-10	75.1
rs:WP_044423532	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	30.30	165	102	3	470	629	3	159	1e-10	71.6
rs:WP_014035379	DNA topoisomerase I [Mycoplasma putrefaciens].	25.43	346	177	11	3	314	4	302	1e-10	74.7
rs:WP_010725465	hypothetical protein, partial [Enterococcus faecium].	39.77	88	46	2	31	111	17	104	1e-10	70.1
rs:WP_009360140	DNA topoisomerase I [alpha proteobacterium HIMB114].	23.27	735	421	31	1	659	1	668	1e-10	75.1
rs:WP_012359104	topoisomerase I [Candidatus Phytoplasma australiense].	24.23	586	365	20	88	644	69	604	1e-10	74.7
tr:A0A086Z290_9BIFI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.81	627	384	20	2	571	6	589	1e-10	75.1
tr:R7TJU1_CAPTE	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	22.90	572	372	22	46	587	59	591	1e-10	75.1
rs:XP_004381055	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Trichechus manatus latirostris].	23.33	463	287	18	188	616	239	667	1e-10	75.1
tr:S8G2P0_FOMPI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.08	634	401	23	3	584	7	599	1e-10	75.1
rs:WP_030169091	MULTISPECIES: DNA topoisomerase I [Actinomycetales].	23.91	598	325	23	2	530	17	553	1e-10	75.1
rs:WP_020262396	hypothetical protein [Aminicenantes bacterium SCGC AAA252-O11].	23.25	572	369	19	90	629	67	600	2e-10	75.1
gp:CP003149_4723	DNA topoisomerase I [Pseudomonas aeruginosa DK2]	22.46	512	290	18	74	537	11	463	2e-10	74.7
rs:WP_012422574	DNA topoisomerase I [Borrelia hermsii].	23.54	548	327	20	77	577	69	571	2e-10	75.1
rs:WP_001977345	DNA topoisomerase [Helicobacter pylori].	23.29	468	307	13	99	537	77	521	2e-10	74.7
tr:W5UTM6_9MOLU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.33	661	417	28	2	629	3	593	2e-10	74.7
rs:WP_013767752	DNA topoisomerase I [Haliscomenobacter hydrossis].	24.67	377	225	13	157	500	132	482	2e-10	75.1
rs:WP_027460080	DNA topoisomerase I [Deinococcus murrayi].	23.53	595	328	23	3	530	5	539	2e-10	75.1
rs:WP_029511832	DNA topoisomerase I [Mesoplasma grammopterae].	22.88	673	401	26	3	625	5	609	2e-10	74.7
rs:WP_001926398	DNA topoisomerase [Helicobacter pylori].	23.83	470	302	14	99	537	77	521	2e-10	74.7
rs:WP_039027048	DNA topoisomerase I [Pseudomonas aeruginosa].	21.87	503	304	16	74	537	59	511	2e-10	74.7
tr:W2FWD4_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETK75057.1};	24.47	568	341	24	1	519	1	529	2e-10	75.1
rs:WP_013939575	DNA topoisomerase I [Myxococcus fulvus].	22.89	629	379	28	76	640	125	711	2e-10	75.1
rs:WP_033379005	MULTISPECIES: DNA topoisomerase I, partial [Mycoplasma].	21.33	661	417	28	2	629	3	593	2e-10	74.7
tr:W1Y7F5_9ZZZZ	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ETJ37625.1}; Flags: Fragment;	38.89	90	55	0	462	551	1	90	2e-10	69.3
tr:A0A096RLJ4_MAIZE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.12	346	223	11	188	521	49	363	2e-10	73.6
tr:K1TBN0_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central {ECO:0000313|EMBL:EKC64879.1}; Flags: Fragment;	25.74	408	238	14	3	392	5	365	2e-10	73.6
rs:WP_035240901	DNA topoisomerase I [Desulfobacter vibrioformis].	22.74	585	380	18	82	630	59	607	2e-10	74.7
rs:WP_027413100	DNA topoisomerase I [Aquimarina muelleri].	25.78	384	244	13	154	526	128	481	2e-10	75.1
rs:WP_003792156	DNA topoisomerase I [Kingella kingae].	21.20	665	421	22	76	679	53	675	2e-10	74.7
rs:WP_038651466	DNA topoisomerase I [Prochlorococcus sp. MIT 0801].	23.85	566	330	22	3	519	7	520	2e-10	75.1
rs:WP_019618173	hypothetical protein [Pseudoclavibacter faecalis].	22.58	598	337	22	2	530	4	544	2e-10	75.1
rs:WP_031637565	DNA topoisomerase I [Pseudomonas aeruginosa].	21.91	598	319	22	1	537	1	511	2e-10	74.7
rs:XP_007048480	Topoisomerase 3alpha isoform 1 [Theobroma cacao].	21.82	417	275	12	188	585	215	599	2e-10	75.1
rs:WP_031331786	DNA topoisomerase I [Williamsia sp. D3].	23.91	598	325	23	2	530	17	553	2e-10	75.1
tr:J9Z2K6_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.93	514	328	15	85	564	62	546	2e-10	74.7
tr:V8D3C4_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.91	598	325	23	2	530	22	558	2e-10	75.1
rs:WP_008287348	topoisomerase [Hydrogenivirga sp. 128-5-R1-1].	24.62	528	294	22	81	576	687	1142	2e-10	75.1
rs:WP_023101907	DNA topoisomerase I [Pseudomonas aeruginosa].	23.12	519	278	19	74	537	59	511	2e-10	74.7
rs:WP_027359053	DNA topoisomerase I [Desulforegula conservatrix].	22.14	569	375	17	74	610	51	583	2e-10	74.7
rs:WP_030989852	DNA topoisomerase I [Streptomyces sp. NRRL S-1813].	23.15	596	330	22	2	530	14	548	2e-10	75.1
rs:WP_023931611	DNA topoisomerase III [Photobacterium leiognathi].	36.04	111	61	4	2	108	3	107	2e-10	70.1
rs:WP_041485569	hypothetical protein, partial [alpha proteobacterium HIMB59].	23.93	514	328	15	85	564	62	546	2e-10	74.7
rs:WP_033619286	DNA topoisomerase I [Helicobacter pylori].	25.00	496	308	18	80	537	52	521	2e-10	74.7
sp:TOP1_MYCGA	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	22.45	628	390	24	103	673	104	691	2e-10	74.7
tr:A0A067FIC2_CITSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.17	386	236	18	64	413	113	485	2e-10	74.3
rs:WP_035396024	hypothetical protein, partial [Chloroflexi bacterium SCGC AB-629-P13].	23.90	611	363	25	79	629	57	625	2e-10	74.7
rs:WP_026366250	hypothetical protein [Salinicoccus albus].	33.62	116	64	4	3	110	4	114	2e-10	70.1
rs:WP_015637930	DNA topoisomerase I [Candidatus Phytoplasma australiense].	24.23	586	365	20	88	644	69	604	2e-10	74.7
tr:A0A0D3FE72_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OBART03G04820.2};	25.90	251	149	7	188	418	186	419	2e-10	74.7
rs:WP_034005999	DNA topoisomerase I [Pseudomonas aeruginosa].	22.35	519	282	18	74	537	59	511	2e-10	74.7
tr:A0A0A2LBI9_PENIT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.84	625	361	25	3	560	6	582	2e-10	74.7
tr:E1YHR2_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.05	582	372	24	83	629	60	606	2e-10	74.7
rs:XP_002495860	ZYRO0C04642p [Zygosaccharomyces rouxii].	22.29	664	398	22	3	584	4	631	2e-10	74.7
rs:XP_003687892	hypothetical protein TPHA_0L01010 [Tetrapisispora phaffii CBS 4417].	23.60	627	336	27	3	537	4	579	2e-10	74.3
rs:WP_037958625	DNA topoisomerase I [Sulfurospirillum sp. SCADC].	22.09	652	392	21	3	614	13	588	2e-10	74.7
rs:WP_022901482	DNA topoisomerase I [Humibacter albus].	23.39	590	335	19	2	528	5	540	2e-10	74.7
rs:XP_012603375	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Microcebus murinus].	22.52	484	306	16	188	634	156	607	2e-10	74.7
tr:X0RE35_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.04	586	382	20	77	629	104	653	2e-10	74.7
tr:A0A067FLZ1_CITSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.17	386	236	18	64	413	112	484	2e-10	74.3
rs:WP_026004456	DNA topoisomerase I [Streptomyces sp. AA1529].	23.37	612	326	23	2	530	13	564	2e-10	74.7
tr:A0A0D3FE74_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OBART03G04820.4};	25.90	251	149	7	188	418	186	419	2e-10	74.7
tr:A0A078C0P1_BRANA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.90	642	407	29	32	618	388	996	2e-10	75.1
tr:W4PQ42_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.31	249	161	6	77	314	54	293	2e-10	72.4
rs:WP_004571867	MULTISPECIES: DNA topoisomerase I [Streptomyces].	23.62	597	327	22	2	530	14	549	2e-10	74.7
rs:WP_030374829	MULTISPECIES: DNA topoisomerase I [Streptomyces].	23.62	597	327	22	2	530	14	549	2e-10	74.7
tr:U4L9N6_PYROM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.13	562	348	22	3	520	12	533	2e-10	74.3
tr:A0A090LCN1_STRRB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.28	395	252	11	188	560	220	581	2e-10	74.7
rs:WP_044495257	DNA topoisomerase I [Nesterenkonia sp. NP1].	22.34	591	349	20	2	530	17	559	2e-10	74.7
rs:XP_001785482	predicted protein [Physcomitrella patens].	20.25	706	452	27	3	634	8	676	2e-10	74.7
rs:WP_044402915	DNA topoisomerase I [Lacinutrix sp. Hel_I_90].	24.06	532	332	17	3	521	5	477	2e-10	74.7
rs:XP_003646048	hypothetical protein Ecym_4154 [Eremothecium cymbalariae DBVPG#7215].	24.17	422	262	11	174	564	205	599	2e-10	74.3
rs:WP_001902295	DNA topoisomerase [Helicobacter pylori].	22.73	484	322	13	82	537	61	520	2e-10	74.3
rs:WP_021668946	toprim domain protein, partial [Prevotella disiens].	32.59	135	64	5	4	117	5	133	2e-10	70.5
rs:WP_031693912	DNA topoisomerase I [Pseudomonas aeruginosa].	22.82	517	282	19	74	537	59	511	2e-10	74.3
rs:XP_004381056	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Trichechus manatus latirostris].	23.33	463	287	18	188	616	144	572	2e-10	74.7
rs:WP_019070269	DNA topoisomerase I [Streptomyces sp. R1-NS-10].	22.91	598	329	21	2	530	13	547	2e-10	74.7
rs:WP_042808036	DNA topoisomerase I [Streptomyces rimosus].	23.62	597	327	22	2	530	14	549	2e-10	74.7
rs:WP_025406842	DNA topoisomerase I [Borrelia hermsii].	23.54	548	327	20	77	577	69	571	2e-10	74.7
rs:WP_034388160	DNA topoisomerase I [Deinococcus sp. YIM 77859].	23.35	501	305	16	77	530	68	536	2e-10	74.7
rs:WP_007209260	MULTISPECIES: topoisomerase [Bacilli].	39.17	120	69	1	103	218	3	122	2e-10	70.1
rs:WP_003827625	DNA topoisomerase I [Bifidobacterium angulatum].	22.57	647	364	23	2	571	6	592	2e-10	74.7
tr:G0V1K6_TRYCI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.79	635	424	20	3	598	5	599	2e-10	74.7
rs:WP_047247320	DNA topoisomerase I [Maribacter thermophilus].	27.01	374	238	11	157	521	132	479	2e-10	74.7
tr:Q1QKM0_NITHX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.84	696	405	32	1	629	26	656	2e-10	74.7
rs:WP_033596248	DNA topoisomerase I [Helicobacter pylori].	25.00	496	308	18	80	537	52	521	2e-10	74.3
rs:WP_045920564	DNA topoisomerase I [Bifidobacterium angulatum].	22.57	647	364	23	2	571	6	592	2e-10	74.7
rs:WP_023093022	DNA topoisomerase I [Pseudomonas aeruginosa].	22.46	512	290	18	74	537	59	511	2e-10	74.3
rs:WP_038569546	DNA topoisomerase I [Dermacoccus nishinomiyaensis].	23.39	620	367	22	2	563	6	575	2e-10	74.7
rs:WP_034266482	DNA topoisomerase I [Actinospica robiniae].	22.47	592	340	21	2	530	13	548	2e-10	74.7
rs:WP_012170389	DNA topoisomerase I [Azorhizobium caulinodans].	23.07	698	404	34	1	630	1	633	2e-10	74.7
rs:WP_026937567	DNA topoisomerase I [Gulosibacter molinativorax].	24.11	593	327	23	3	528	5	541	2e-10	74.7
rs:WP_023648458	DNA topoisomerase I [Candidatus Pelagibacter ubique].	22.55	572	345	23	1	534	1	512	2e-10	74.7
rs:WP_011734472	DNA topoisomerase I [Pelobacter propionicus].	21.64	744	432	29	3	660	5	683	2e-10	74.7
gp:HF952106_1036	DNA topoisomerase I [Streptococcus agalactiae ILRI112]	24.81	387	230	17	269	630	12	362	2e-10	73.6
rs:WP_026889209	DNA topoisomerase I [Clostridium beijerinckii].	23.39	667	375	28	2	616	4	586	2e-10	74.3
rs:WP_018562195	DNA topoisomerase I [Streptomyces sp. BoleA5].	22.74	598	332	24	2	530	14	550	2e-10	74.7
rs:WP_006943967	DNA topoisomerase I [Dermacoccus sp. Ellin185].	23.39	620	367	22	2	563	6	575	2e-10	74.7
rs:WP_017191419	hypothetical protein [Poinsettia branch-inducing phytoplasma].	22.71	590	370	21	70	630	53	585	2e-10	74.3
rs:WP_041358070	DNA topoisomerase I [Nitrobacter hamburgensis].	22.70	696	406	32	1	629	1	631	2e-10	74.7
rs:WP_007365501	DNA topoisomerase I [Porphyromonas uenonis].	22.80	535	336	18	3	520	7	481	2e-10	74.7
rs:WP_043023131	DNA topoisomerase I [Lactobacillus brevis].	21.68	595	372	23	88	635	78	625	2e-10	74.3
rs:WP_013045489	DNA topoisomerase I [Candidatus Puniceispirillum marinum].	24.45	687	406	32	1	629	1	632	2e-10	74.7
rs:XP_010598538	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Loxodonta africana].	23.22	521	324	20	188	667	156	641	2e-10	74.7
rs:WP_033064059	DNA topoisomerase I [Clostridium botulinum].	25.80	659	369	31	3	616	5	588	2e-10	74.3
rs:WP_022966647	topoisomerase I [Pseudomonas caeni].	20.30	601	386	16	74	631	84	634	2e-10	74.7
rs:WP_004132171	DNA topoisomerase I [Gardnerella vaginalis].	24.32	629	360	26	2	571	6	577	2e-10	74.7
rs:WP_001935019	DNA topoisomerase [Helicobacter pylori].	23.95	522	332	17	103	583	73	570	2e-10	74.3
rs:XP_005650322	DNA topoisomerase I [Coccomyxa subellipsoidea C-169].	22.15	623	396	22	55	616	43	637	2e-10	74.7
rs:WP_044187322	DNA topoisomerase I [Porphyromonas sp. COT-290 OH860].	25.27	459	292	15	76	521	57	477	2e-10	74.3
rs:XP_012708409	PREDICTED: DNA topoisomerase 3-alpha [Fundulus heteroclitus].	23.17	492	295	19	188	634	252	705	2e-10	74.7
rs:WP_033587927	DNA topoisomerase I [Helicobacter pylori].	24.54	538	336	20	80	574	52	562	2e-10	74.3
rs:WP_038029314	DNA topoisomerase I [Thermonema rossianum].	25.65	347	218	10	187	520	162	481	2e-10	74.3
rs:WP_040527233	DNA topoisomerase I [Gordonia paraffinivorans].	24.32	588	335	23	2	530	16	552	2e-10	74.7
rs:WP_030597724	DNA topoisomerase I [Streptomyces rimosus].	23.62	597	327	22	2	530	14	549	2e-10	74.7
rs:WP_024550709	hypothetical protein, partial [Cronobacter turicensis].	27.01	348	224	9	73	401	74	410	2e-10	73.6
rs:WP_024525219	DNA topoisomerase I [Lactobacillus brevis].	21.68	595	372	23	88	635	78	625	2e-10	74.3
rs:WP_017613841	DNA topoisomerase I [Nocardiopsis salina].	22.51	724	388	33	3	632	25	669	2e-10	74.7
rs:WP_033973126	DNA topoisomerase I [Pseudomonas aeruginosa].	22.82	517	282	19	74	537	59	511	2e-10	74.3
rs:XP_012603376	PREDICTED: DNA topoisomerase 3-alpha isoform X4 [Microcebus murinus].	22.52	484	306	16	188	634	149	600	2e-10	74.7
rs:WP_016574364	MULTISPECIES: DNA topoisomerase I [Streptomyces].	23.79	597	326	23	2	530	14	549	2e-10	74.7
rs:WP_032090097	DNA topoisomerase I [bacterium LF-3].	23.23	650	388	26	2	614	4	579	2e-10	74.3
rs:WP_000681456	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	2e-10	74.3
rs:WP_013680298	topoisomerase [Thermoproteus uzoniensis].	22.52	444	261	15	164	581	834	1220	2e-10	74.7
rs:WP_000277572	DNA topoisomerase I [Helicobacter pylori].	23.29	468	307	12	99	537	77	521	2e-10	74.3
rs:WP_042447944	DNA topoisomerase I [Streptacidiphilus jiangxiensis].	23.15	596	337	22	2	530	13	554	2e-10	74.7
tr:A4CRQ0_SYNPV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.45	620	387	19	3	572	30	599	2e-10	74.7
rs:XP_009966981	PREDICTED: DNA topoisomerase 3-alpha, partial [Tyto alba].	23.66	486	301	19	188	634	185	639	2e-10	74.7
rs:WP_033901430	DNA topoisomerase I [Pseudomonas sp. FH1].	24.89	470	302	15	84	533	69	507	2e-10	74.3
rs:WP_034968372	DNA topoisomerase I [Campylobacter mucosalis].	23.91	644	390	27	3	614	4	579	2e-10	74.3
rs:WP_010759374	DNA topoisomerase 1 [Enterococcus pallens].	24.19	587	364	25	90	635	68	614	2e-10	74.3
rs:WP_025981576	DNA topoisomerase I [Pseudomonas aeruginosa].	22.93	519	279	19	74	537	59	511	2e-10	74.3
rs:WP_000530573	hypothetical protein, partial [Bacillus cereus].	32.40	179	111	5	510	680	1	177	2e-10	70.9
rs:WP_033744865	DNA topoisomerase I [Helicobacter pylori].	22.66	640	403	24	3	614	4	579	2e-10	74.3
tr:K2D5V3_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.14	682	403	28	3	629	5	613	2e-10	74.3
rs:XP_002864876	hypothetical protein ARALYDRAFT_496584 [Arabidopsis lyrata subsp. lyrata].	21.68	641	395	25	3	585	12	603	2e-10	74.7
rs:WP_008363616	DNA topoisomerase [Mycoplasma sp. G5847].	23.17	574	348	23	97	625	80	605	2e-10	74.3
rs:WP_035589535	DNA topoisomerase I [Elizabethkingia anophelis].	25.38	398	247	14	3	392	5	360	2e-10	74.3
rs:WP_028512772	DNA topoisomerase I [Ruminococcaceae bacterium AE2021].	22.09	652	407	24	2	612	4	595	2e-10	74.3
rs:WP_033760176	DNA topoisomerase I [Helicobacter pylori].	22.66	640	403	24	3	614	4	579	2e-10	74.3
rs:XP_010112124	DNA topoisomerase 1 [Morus notabilis].	22.88	612	377	26	64	610	394	975	2e-10	74.7
rs:WP_043943121	DNA topoisomerase I, partial [Salmonella enterica].	26.61	357	232	12	73	410	74	419	2e-10	73.6
rs:XP_006798035	PREDICTED: DNA topoisomerase 3-alpha-like [Neolamprologus brichardi].	22.89	498	289	19	188	634	256	709	2e-10	74.7
rs:WP_025775846	DNA topoisomerase I, partial [Clostridium botulinum].	26.12	578	334	26	83	616	60	588	2e-10	74.3
rs:WP_031670651	DNA topoisomerase I [Pseudomonas aeruginosa].	23.42	521	276	20	74	537	59	513	2e-10	74.3
rs:WP_008616602	DNA topoisomerase I subunit omega [Magnetospirillum sp. SO-1].	21.39	692	421	25	1	630	1	631	2e-10	74.3
rs:WP_044232760	DNA topoisomerase I [Porphyromonas sp. COT-290 OH3588].	25.27	459	292	15	76	521	57	477	2e-10	74.3
rs:WP_046599101	DNA topoisomerase I [Pseudomonas aeruginosa].	22.35	519	282	18	74	537	59	511	2e-10	73.9
rs:XP_010649353	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Vitis vinifera].	23.36	428	255	14	188	585	211	595	2e-10	74.3
tr:K2ADJ5_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.89	603	378	23	77	629	53	618	2e-10	74.3
tr:E7MMK8_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.60	668	408	25	3	629	15	614	2e-10	74.3
rs:WP_015370680	DNA topoisomerase I [Blattabacterium sp. (Blatta orientalis)].	28.49	365	210	18	39	385	25	356	2e-10	74.3
rs:WP_024948578	DNA topoisomerase I [Helicobacter pylori].	23.78	534	343	18	80	575	52	559	2e-10	74.3
tr:W4RH02_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE43576.1};	36.94	111	66	3	1	107	1	111	2e-10	69.3
rs:WP_006646501	DNA topoisomerase III [Photobacterium sp. SKA34].	35.14	111	62	4	2	108	3	107	2e-10	69.7
rs:XP_006024099	PREDICTED: DNA topoisomerase 3-alpha [Alligator sinensis].	23.44	418	269	15	188	587	156	540	2e-10	74.3
rs:WP_001066140	DNA topoisomerase I [Helicobacter pylori].	23.95	522	332	17	103	583	73	570	2e-10	74.3
rs:WP_024160935	DNA topoisomerase III [Acinetobacter pittii].	29.46	112	71	3	1	109	1	107	2e-10	69.3
rs:WP_030677717	DNA topoisomerase I [Streptomyces rimosus].	23.62	597	327	22	2	530	14	549	2e-10	74.3
rs:WP_001916992	topoisomerase I [Helicobacter pylori].	23.63	546	349	17	80	583	52	571	2e-10	74.3
rs:WP_028098167	DNA topoisomerase I [Dongia sp. URHE0060].	22.40	625	396	25	1	588	1	573	2e-10	74.3
rs:WP_001946791	DNA topoisomerase [Helicobacter pylori].	23.08	468	308	12	99	537	77	521	2e-10	73.9
rs:WP_039660097	DNA topoisomerase III [Pantoea sp. MBLJ3].	31.82	110	69	3	1	108	1	106	2e-10	69.3
rs:WP_039351117	DNA topoisomerase I [Chryseobacterium jeonii].	25.88	398	245	13	3	392	5	360	2e-10	74.3
rs:WP_040627511	DNA topoisomerase I [Solobacterium moorei].	22.60	668	408	25	3	629	4	603	3e-10	74.3
rs:WP_011304445	DNA topoisomerase I [Ehrlichia canis].	25.04	579	325	23	1	534	1	515	3e-10	74.3
rs:WP_018046902	hypothetical protein [Nitrospina sp. AB-629-B06].	24.60	626	387	26	83	667	96	677	3e-10	74.3
rs:WP_039675625	DNA topoisomerase I [Sulfurospirillum sp. MES].	22.26	656	386	21	3	614	8	583	3e-10	73.9
rs:WP_015113376	DNA topoisomerase I [Nostoc sp. PCC 7107].	21.38	622	389	18	3	574	4	575	3e-10	74.3
tr:H2YRK7_CIOSA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.19	623	388	21	3	560	5	589	3e-10	73.9
tr:K1TU90_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC73388.1};	32.26	124	81	2	245	366	22	144	3e-10	70.9
rs:XP_010649355	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Vitis vinifera].	23.36	428	255	14	188	585	211	595	3e-10	74.3
rs:XP_010649354	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Vitis vinifera].	23.36	428	255	14	188	585	211	595	3e-10	74.3
rs:XP_010991894	PREDICTED: DNA topoisomerase 3-alpha [Camelus dromedarius].	23.22	491	294	18	188	634	214	665	3e-10	74.3
rs:WP_001066133	DNA topoisomerase I [Helicobacter pylori].	23.75	522	333	17	103	583	73	570	3e-10	73.9
rs:WP_012703691	DNA topoisomerase I [Clostridium botulinum].	26.30	578	333	27	83	616	60	588	3e-10	73.9
rs:WP_034051068	DNA topoisomerase I [Pseudomonas aeruginosa].	22.49	507	296	18	74	537	59	511	3e-10	73.9
rs:XP_009127141	PREDICTED: uncharacterized protein LOC103851997 isoform X3 [Brassica rapa].	25.18	409	265	16	32	413	387	781	3e-10	74.3
rs:XP_009127134	PREDICTED: uncharacterized protein LOC103851997 isoform X2 [Brassica rapa].	25.18	409	265	16	32	413	387	781	3e-10	74.3
rs:XP_394050	PREDICTED: DNA topoisomerase 3-alpha-like [Apis mellifera].	24.82	568	346	25	46	577	58	580	3e-10	74.3
rs:WP_044730147	DNA topoisomerase I [Mycoplasma hominis].	24.16	596	360	25	73	629	50	592	3e-10	73.9
rs:WP_032072733	DNA topoisomerase I TopA [uncultured bacterium].	21.85	572	370	17	90	631	65	589	3e-10	73.9
rs:WP_002833092	DNA topoisomerase I [Pediococcus pentosaceus].	22.67	569	377	19	90	629	70	604	3e-10	73.9
rs:WP_003638823	DNA topoisomerase I [Lactobacillus pentosus].	22.64	583	374	23	90	635	95	637	3e-10	73.9
rs:WP_019975010	DNA topoisomerase I [Empedobacter brevis].	24.62	455	303	10	77	521	54	478	3e-10	74.3
tr:R4PZ44_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.16	324	212	8	77	392	58	365	3e-10	74.3
tr:K2AAG8_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	24.33	526	300	20	157	629	33	513	3e-10	73.9
rs:WP_031367907	DNA topoisomerase I, partial [Clostridium botulinum].	26.30	578	333	26	83	616	60	588	3e-10	73.9
rs:WP_004440643	DNA topoisomerase I [Clostridium botulinum].	26.47	578	332	27	83	616	60	588	3e-10	73.9
tr:M7CGR0_MORMO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EMP52879.1};	29.57	186	118	4	497	676	16	194	3e-10	70.9
rs:WP_000277563	DNA topoisomerase I [Helicobacter pylori].	22.27	467	312	12	99	537	77	520	3e-10	73.9
tr:M4D449_BRARP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.18	409	265	16	32	413	392	786	3e-10	74.3
rs:WP_033066281	DNA topoisomerase I [Clostridium botulinum].	26.30	578	333	27	83	616	60	588	3e-10	73.9
rs:WP_041495996	DNA topoisomerase I [Nonlabens marinus].	23.46	682	397	26	3	627	5	618	3e-10	74.3
tr:J8F644_BACCE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJQ96454.1};	34.64	179	106	7	495	664	1	177	3e-10	70.9
rs:XP_006973659	PREDICTED: DNA topoisomerase 3-alpha [Peromyscus maniculatus bairdii].	22.76	492	295	17	188	634	239	690	3e-10	74.3
rs:WP_026313436	DNA topoisomerase I [Actinomadura flavalba].	23.69	591	331	22	2	530	19	551	3e-10	74.3
rs:WP_028078437	DNA topoisomerase I [Solobacterium moorei].	22.60	668	408	25	3	629	4	603	3e-10	73.9
tr:M3WMK3_FELCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.20	487	301	16	188	634	239	692	3e-10	74.3
tr:A0A0E0B045_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OGLUM09G02660.4};	25.90	251	149	7	188	418	160	393	3e-10	73.9
rs:WP_021336604	DNA topoisomerase I [Lactobacillus plantarum].	22.64	583	374	23	90	635	95	637	3e-10	73.9
rs:WP_011371807	DNA topoisomerase I [Sulfurimonas denitrificans].	22.22	648	405	26	1	616	1	581	3e-10	73.9
rs:WP_031369395	DNA topoisomerase I, partial [Clostridium botulinum].	26.30	578	333	26	83	616	60	588	3e-10	73.9
tr:A0A0E0B044_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OGLUM09G02660.3};	25.90	251	149	7	188	418	160	393	3e-10	74.3
rs:XP_009127126	PREDICTED: uncharacterized protein LOC103851997 isoform X1 [Brassica rapa].	25.18	409	265	16	32	413	388	782	3e-10	74.3
rs:WP_013325931	DNA topoisomerase I [Sulfurimonas autotrophica].	23.17	656	390	27	1	616	1	582	3e-10	73.9
rs:WP_018775034	MULTISPECIES: DNA topoisomerase I [Arthrobacter].	22.37	590	358	20	2	538	10	552	3e-10	74.3
rs:WP_002592111	hypothetical protein [[Clostridium] clostridioforme].	32.46	114	61	4	1	107	1	105	3e-10	68.9
rs:XP_002562369	Pc18g05420 [Penicillium rubens Wisconsin 54-1255].	23.21	616	376	23	3	560	6	582	3e-10	73.9
rs:WP_033749012	DNA topoisomerase I [Helicobacter pylori].	23.46	520	337	16	103	583	73	570	3e-10	73.9
rs:WP_015473756	DNA topoisomerase 1 [Lactobacillus brevis].	21.68	595	372	23	88	635	78	625	3e-10	73.9
rs:XP_003996416	PREDICTED: DNA topoisomerase 3-alpha [Felis catus].	23.30	485	301	16	188	634	239	690	3e-10	74.3
rs:WP_009871082	Topoisomerase IA [Magnetospirillum magnetotacticum].	21.26	696	417	26	1	630	1	631	3e-10	74.3
tr:A0A0D9Z2H5_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OGLUM03G04650.3};	26.20	229	136	6	188	396	165	380	3e-10	73.9
rs:WP_012504231	topoisomerase I [Candidatus Phytoplasma mali].	23.95	593	366	24	2	572	3	532	3e-10	73.9
rs:WP_017322230	DNA topoisomerase I [cyanobacterium PCC 7702].	23.09	615	390	19	3	573	4	579	3e-10	74.3
rs:WP_016437384	DNA topoisomerase 1 [Streptomyces sp. HGB0020].	22.47	592	339	21	2	530	13	547	3e-10	74.3
rs:WP_012720956	DNA topoisomerase I [Clostridium botulinum].	25.42	657	374	29	3	616	5	588	3e-10	73.9
rs:WP_004280500	DNA topoisomerase I [Leptospira borgpetersenii].	24.24	590	373	19	76	629	52	603	3e-10	73.9
tr:A0A078GNX0_BRANA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.18	409	265	16	32	413	394	788	3e-10	74.3
tr:S9PZ31_SCHOY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.92	612	398	18	3	565	4	578	3e-10	73.9
rs:WP_027186352	DNA topoisomerase I [Desulfovibrio inopinatus].	22.33	600	391	21	76	639	53	613	3e-10	73.9
rs:WP_002762881	DNA topoisomerase I [Leptospira borgpetersenii].	24.15	588	376	19	76	629	52	603	3e-10	73.9
rs:WP_021902669	DNA topoisomerase [Porphyromonas sp. CAG:1061].	23.00	526	349	14	3	523	5	479	3e-10	73.9
tr:F6IRS7_LACPE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.64	583	374	23	90	635	95	637	3e-10	73.9
rs:WP_014412923	DNA topoisomerase I [Rickettsia australis].	22.21	689	414	24	1	629	1	627	3e-10	73.9
rs:WP_004574556	DNA topoisomerase I [Gardnerella vaginalis].	23.60	627	367	24	2	571	6	577	3e-10	74.3
tr:A0A034U040_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAJ77702.1};	36.26	91	58	0	486	576	8	98	3e-10	68.9
rs:XP_012603377	PREDICTED: DNA topoisomerase 3-alpha isoform X5 [Microcebus murinus].	22.52	484	306	16	188	634	52	503	3e-10	73.9
tr:B9FBH7_ORYSJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.20	229	136	6	188	396	319	534	3e-10	74.3
rs:WP_036118829	DNA topoisomerase I [Mangrovimonas yunxiaonensis].	26.70	382	234	13	154	521	128	477	3e-10	73.9
rs:WP_038005493	DNA topoisomerase I [Synechococcus sp. WH 7805].	21.45	620	387	19	3	572	5	574	3e-10	73.9
rs:WP_001066132	DNA topoisomerase I [Helicobacter pylori].	24.40	545	345	19	80	583	52	570	3e-10	73.9
gp:AC104428_4	Putative DNA topoisomerase III [Oryza sativa Japonica Group]	26.70	221	145	5	188	396	319	534	3e-10	73.9
tr:L7LY29_9ACAR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.25	400	238	15	188	560	207	564	3e-10	73.9
rs:WP_000681405	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	24	3	614	4	579	3e-10	73.9
rs:WP_009577130	DNA topoisomerase I, partial [gamma proteobacterium IMCC3088].	27.91	344	206	13	72	391	87	412	3e-10	73.2
rs:WP_001955723	DNA topoisomerase [Helicobacter pylori].	23.29	468	307	13	99	537	77	521	3e-10	73.9
rs:WP_039774455	DNA topoisomerase I [Clostridium botulinum].	25.27	657	375	28	3	616	5	588	3e-10	73.9
tr:A0A0D3FE71_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OBART03G04820.1};	25.90	251	149	7	188	418	277	510	3e-10	73.9
rs:WP_011772762	DNA topoisomerase I [Borrelia turicatae].	24.13	547	325	22	77	577	69	571	3e-10	73.9
tr:A0A0D9Z2H3_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OGLUM03G04650.1};	26.20	229	136	6	188	396	173	388	3e-10	73.9
tr:W5VU31_SALTM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AHH86158.1}; Flags: Fragment;	31.15	183	113	4	500	676	3	178	3e-10	70.5
rs:WP_043497076	DNA topoisomerase I [Georgenia sp. SUBG003].	22.47	623	374	21	2	560	6	583	3e-10	73.9
rs:WP_013585761	DNA topoisomerase I [Microbacterium testaceum].	22.02	595	353	19	2	538	6	547	3e-10	73.9
rs:WP_033982829	DNA topoisomerase I [Pseudomonas aeruginosa].	23.22	521	277	20	74	537	59	513	3e-10	73.6
rs:WP_014431876	DNA topoisomerase I [Caldilinea aerophila].	22.68	604	318	21	2	530	4	533	3e-10	73.9
tr:A0A0D9Z2H4_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OGLUM03G04650.2};	26.20	229	136	6	188	396	173	388	3e-10	73.9
rs:WP_044441756	DNA topoisomerase I [Agreia bicolorata].	22.64	605	331	21	2	530	6	549	3e-10	73.9
rs:WP_030412618	DNA topoisomerase I [Streptomyces sp. NRRL S-1448].	23.14	592	336	22	2	530	14	549	3e-10	73.9
rs:WP_023103391	DNA topoisomerase I [Pseudomonas aeruginosa].	22.76	514	286	18	74	537	59	511	3e-10	73.6
rs:WP_025419976	DNA topoisomerase I [Borrelia anserina].	23.53	544	332	18	77	577	69	571	3e-10	73.9
rs:WP_015211400	DNA topoisomerase I [Cylindrospermum stagnale].	21.44	611	386	17	3	566	4	567	3e-10	73.9
rs:WP_046932689	hypothetical protein [Xanthomonas perforans].	21.77	643	405	22	82	675	62	655	3e-10	73.6
rs:WP_033788533	DNA topoisomerase I [Helicobacter pylori].	25.00	488	304	17	80	531	52	513	3e-10	73.6
rs:WP_013447026	DNA topoisomerase I [Riemerella anatipestifer].	25.21	484	297	16	76	538	52	491	3e-10	73.9
tr:F7JLD5_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGN30496.1};	28.65	178	119	3	497	669	14	188	3e-10	70.9
rs:WP_031939868	DNA topoisomerase I [Rhodococcus defluvii].	22.54	590	338	20	2	528	17	550	3e-10	73.9
rs:WP_031852978	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	26.04	361	228	11	75	413	86	429	3e-10	73.2
rs:XP_010444313	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha-like [Camelina sativa].	21.29	634	406	24	3	585	12	603	3e-10	73.9
rs:WP_001066154	DNA topoisomerase I [Helicobacter pylori].	23.95	522	332	17	103	583	73	570	3e-10	73.6
rs:WP_017569354	DNA topoisomerase I [Nocardiopsis halotolerans].	22.77	593	336	23	3	530	25	560	3e-10	73.9
rs:WP_029038870	DNA topoisomerase I [Salinimicrobium xinjiangense].	27.11	380	231	14	157	521	132	480	3e-10	73.9
rs:WP_019987069	DNA topoisomerase I [Rudanella lutea].	25.31	403	245	12	3	392	5	364	3e-10	73.9
rs:WP_027122172	DNA topoisomerase I [Mycoplasma imitans].	23.17	587	346	23	88	614	86	627	3e-10	73.9
rs:WP_000246606	hypothetical protein, partial [Streptococcus agalactiae].	25.68	331	222	12	103	415	99	423	3e-10	73.2
rs:WP_016663290	DNA topoisomerase I [Dermabacter sp. HFH0086].	22.19	658	376	24	3	585	6	602	3e-10	73.9
rs:WP_028483388	MULTISPECIES: DNA topoisomerase I [unclassified Aminicenantes].	23.08	572	370	19	90	629	67	600	3e-10	73.9
rs:WP_008666735	DNA topoisomerase I [Rhodopirellula europaea].	22.09	593	331	18	3	530	33	559	3e-10	73.9
rs:WP_008661721	DNA topoisomerase I [Rhodopirellula europaea].	22.09	593	331	18	3	530	33	559	3e-10	73.9
rs:WP_021731562	DNA topoisomerase I [Lactobacillus plantarum].	22.64	583	374	23	90	635	95	637	3e-10	73.6
rs:WP_021596265	DNA topoisomerase I [Actinomadura madurae].	24.01	554	330	17	32	530	14	531	3e-10	73.9
rs:WP_005801708	hypothetical protein [Bacteroides fragilis].	35.00	120	61	3	1	109	1	114	3e-10	68.9
tr:F6YMD1_HORSE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.69	498	288	18	188	634	220	671	3e-10	73.9
rs:WP_016628540	hypothetical protein [Enterococcus faecium].	38.84	121	70	1	103	219	3	123	3e-10	69.7
rs:WP_034030652	DNA topoisomerase I [Pseudomonas aeruginosa].	21.21	627	354	22	74	641	59	604	4e-10	73.6
rs:WP_016751161	DNA topoisomerase I [Leptospira kirschneri].	23.89	674	382	25	3	630	4	592	4e-10	73.6
tr:T1BKU1_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EQD53929.1};	23.58	564	349	18	3	534	23	536	4e-10	73.9
tr:V8C8D1_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.77	584	389	20	76	629	99	650	4e-10	73.9
rs:WP_044558127	hypothetical protein, partial [Bacteriovorax marinus].	22.91	633	380	24	3	587	65	637	4e-10	73.9
rs:XP_004896709	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Heterocephalus glaber].	22.58	465	294	15	188	619	239	670	4e-10	73.9
rs:WP_028463728	DNA topoisomerase I [Nocardia sp. 348MFTsu5.1].	23.13	601	325	21	2	530	17	552	4e-10	73.9
rs:WP_045165808	reverse gyrase [Thermoanaerobacter cellulolyticus].	23.20	500	278	19	66	536	648	1070	4e-10	73.9
rs:YP_007418204	DNA topoisomerase 1 [Megavirus lba].	24.39	578	305	26	3	521	4	508	4e-10	73.9
tr:K3Y2H4_SETIT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.05	403	236	18	27	391	325	703	4e-10	73.9
rs:WP_022158785	DNA topoisomerase [Prevotella sp. CAG:520].	23.22	603	366	20	3	580	5	535	4e-10	73.9
rs:WP_034561232	DNA topoisomerase I [Helicobacter macacae].	22.77	584	389	20	76	629	49	600	4e-10	73.6
rs:WP_013992519	DNA topoisomerase I [Zobellia galactanivorans].	24.86	531	331	16	3	521	5	479	4e-10	73.9
gp:CP002011_2285	DNA topoisomerase [Clostridium botulinum F str. 230613]	25.42	657	374	29	3	616	9	592	4e-10	73.6
tr:A0A094A6C6_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY22823.1};	22.28	570	365	20	3	533	6	536	4e-10	73.9
tr:D7WBB2_9CORY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	548	318	24	38	530	44	553	4e-10	73.9
rs:WP_012410891	DNA topoisomerase I [Nostoc punctiforme].	20.87	623	387	19	3	572	4	573	4e-10	73.9
rs:WP_047034554	DNA topoisomerase I [Elizabethkingia meningoseptica].	25.38	398	247	14	3	392	5	360	4e-10	73.9
rs:WP_012349580	topoisomerase [Pyrobaculum neutrophilum].	21.04	599	364	19	30	598	712	1231	4e-10	73.9
rs:WP_001954070	DNA topoisomerase [Helicobacter pylori].	22.48	467	311	12	99	537	77	520	4e-10	73.6
rs:XP_001918241	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha [Equus caballus].	22.69	498	288	18	188	634	219	670	4e-10	73.9
rs:WP_025986837	DNA topoisomerase I [Pseudomonas aeruginosa].	23.06	503	298	17	74	537	59	511	4e-10	73.6
rs:WP_041530992	reverse gyrase [Persephonella marina].	23.08	611	363	22	3	581	608	1143	4e-10	73.9
rs:WP_015086777	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	23	3	614	4	579	4e-10	73.6
tr:S5DMR7_9ACTN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.00	440	240	18	3	392	5	404	4e-10	73.9
rs:XP_004669091	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Jaculus jaculus].	22.25	481	311	15	188	634	239	690	4e-10	73.9
rs:XP_002155556	PREDICTED: uncharacterized protein LOC100215195 [Hydra vulgaris].	21.65	679	434	26	3	603	520	1178	4e-10	73.9
rs:WP_036503429	DNA topoisomerase I [Nitrosococcus oceani].	22.22	576	353	22	3	534	5	529	4e-10	73.6
rs:WP_034038751	DNA topoisomerase I [Pseudomonas aeruginosa].	20.34	708	393	26	1	641	1	604	4e-10	73.6
gp:CP006916_724	DNA topoisomerase I [Mycoplasma gallisepticum S6]	22.70	564	344	21	103	614	104	627	4e-10	73.6
rs:NP_986566	AGL101Cp [Ashbya gossypii ATCC 10895].	22.60	593	377	17	3	543	4	566	4e-10	73.6
rs:WP_004415122	DNA topoisomerase I [Mycoplasma arginini].	22.78	619	373	22	73	641	50	613	4e-10	73.6
rs:WP_011183550	DNA topoisomerase I [Mesoplasma florum].	22.73	673	402	26	3	625	5	609	4e-10	73.6
rs:WP_009086613	MULTISPECIES: DNA topoisomerase I [Elizabethkingia].	25.38	398	247	14	3	392	5	360	4e-10	73.9
gp:MYCRRN1_17	DNA topoisomerase I [Mycoplasma gallisepticum]	22.70	564	344	21	103	614	104	627	4e-10	73.6
rs:WP_024775835	DNA topoisomerase I [Arcobacter cibarius].	23.90	661	393	25	3	617	4	600	4e-10	73.6
rs:WP_014937682	DNA topoisomerase I [Riemerella anatipestifer].	25.62	484	295	17	76	538	52	491	4e-10	73.6
rs:WP_042831491	DNA topoisomerase I [Streptomyces rimosus].	23.62	597	327	22	2	530	14	549	4e-10	73.9
rs:WP_031012614	DNA topoisomerase I [Streptomyces sp. NRRL WC-3773].	23.35	591	336	22	2	530	14	549	4e-10	73.9
rs:WP_031684974	DNA topoisomerase I [Pseudomonas aeruginosa].	22.82	517	282	19	74	537	59	511	4e-10	73.6
tr:M7XAM1_RHOT1	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EMS20774.1};	21.99	632	405	24	3	584	6	599	4e-10	73.9
rs:WP_030880763	DNA topoisomerase I [Streptomyces varsoviensis].	22.58	598	333	22	2	530	13	549	4e-10	73.9
rs:WP_029455134	DNA topoisomerase I [Candidatus Pelagibacter ubique].	22.05	576	343	19	1	534	1	512	4e-10	73.6
tr:G9P528_HYPAI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHK41268.1};	22.00	559	352	20	3	520	4	519	4e-10	73.6
tr:K7YVL8_9VIRU	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:AFX92358.1};	24.39	578	305	26	3	521	4	508	4e-10	73.6
rs:WP_003134111	DNA topoisomerase I [Pseudomonas aeruginosa].	22.72	515	285	19	74	537	59	511	4e-10	73.6
rs:WP_020971805	DNA topoisomerase I [Helicobacter pylori].	22.66	640	403	24	3	614	4	579	4e-10	73.6
rs:XP_007376371	DNA topoisomerase [Spathaspora passalidarum NRRL Y-27907].	21.92	634	403	21	3	584	4	597	4e-10	73.6
rs:WP_011128730	DNA topoisomerase I [Synechococcus sp. WH 8102].	21.89	530	331	18	90	572	81	574	4e-10	73.9
rs:WP_040423432	DNA topoisomerase I [Corynebacterium genitalium].	25.00	548	318	24	38	530	27	536	4e-10	73.9
tr:A0A0E0CKE8_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OMERI02G16280.7};	23.33	493	307	20	39	480	310	782	4e-10	73.9
rs:NP_584791	DNA TOPOISOMERASE III [Encephalitozoon cuniculi GB-M1].	22.44	499	323	16	99	573	1	459	4e-10	73.6
rs:WP_023123989	DNA topoisomerase I [Pseudomonas aeruginosa].	22.93	519	281	20	74	537	59	513	4e-10	73.6
rs:WP_012151940	DNA topoisomerase I [Rickettsia bellii].	22.68	679	425	24	1	630	1	628	4e-10	73.6
rs:WP_005006203	DNA topoisomerase I [Acinetobacter ursingii].	21.51	581	378	23	76	611	55	602	4e-10	73.6
rs:WP_035939843	DNA topoisomerase I [Knoellia aerolata].	23.47	588	337	22	2	530	12	545	4e-10	73.9
tr:B8ANX5_ORYSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.20	229	136	6	188	396	319	534	4e-10	73.9
rs:XP_001453271	hypothetical protein [Paramecium tetraurelia strain d4-2].	21.49	619	409	20	3	583	16	595	4e-10	73.6
rs:WP_001924885	DNA topoisomerase [Helicobacter pylori].	22.70	467	310	12	99	537	77	520	4e-10	73.6
rs:XP_001441837	hypothetical protein [Paramecium tetraurelia strain d4-2].	21.42	635	406	20	3	591	16	603	4e-10	73.6
rs:WP_001953676	DNA topoisomerase [Helicobacter pylori].	23.82	487	314	15	82	537	61	521	4e-10	73.2
tr:E1X628_BACMS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.53	544	337	20	90	587	141	651	4e-10	73.6
tr:B1II68_CLOBK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.42	657	374	29	3	616	9	592	4e-10	73.6
rs:WP_014886238	DNA topoisomerase I [Mycoplasma gallisepticum].	22.56	563	346	21	103	614	104	627	4e-10	73.6
rs:WP_029667409	hypothetical protein, partial [Calescamantes bacterium JGI 0000106-N5].	25.05	547	333	18	83	583	10	525	4e-10	73.2
rs:WP_020593538	hypothetical protein [Kiloniella laminariae].	23.08	637	401	24	55	630	27	635	4e-10	73.6
rs:WP_042520547	DNA topoisomerase I [Lactobacillus brevis].	21.68	595	372	23	88	635	78	625	4e-10	73.6
rs:WP_031903954	DNA topoisomerase III, partial [Staphylococcus aureus].	36.11	144	75	6	3	135	4	141	4e-10	69.3
rs:WP_043088831	DNA topoisomerase I [Pseudomonas aeruginosa].	22.05	517	286	18	74	537	59	511	4e-10	73.2
rs:WP_001929217	DNA topoisomerase [Helicobacter pylori].	23.29	468	307	12	99	537	9	453	4e-10	73.2
rs:WP_045716257	DNA topoisomerase I, partial [Salmonella enterica].	26.61	357	232	12	73	410	74	419	4e-10	72.8
rs:WP_000655366	DNA topoisomerase I [Helicobacter pylori].	23.39	543	348	17	83	583	55	571	4e-10	73.6
rs:WP_019396332	DNA topoisomerase I [Pseudomonas aeruginosa].	22.42	513	289	17	74	537	59	511	4e-10	73.2
rs:XP_008367818	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha-like [Malus domestica].	24.03	437	277	14	3	396	8	432	4e-10	73.2
rs:WP_004916145	DNA topoisomerase I [Riemerella anatipestifer].	25.62	484	295	17	76	538	52	491	4e-10	73.6
rs:WP_021347695	DNA topoisomerase I [Elizabethkingia meningoseptica].	25.38	398	247	14	3	392	5	360	4e-10	73.6
tr:I1QMB1_ORYGL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.34	243	158	7	188	418	402	635	4e-10	73.9
tr:U2JN23_PORGN	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ERJ81437.1}; Flags: Fragment;	39.62	106	51	4	41	135	2	105	4e-10	68.9
tr:A0A078AU55_STYLE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.07	655	382	23	1	576	5	603	4e-10	73.6
tr:A0A077EBF0_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.66	329	211	11	72	392	21	330	4e-10	73.6
rs:WP_020985551	DNA topoisomerase I [Leptospira kmetyi].	22.54	670	406	24	3	630	4	602	4e-10	73.2
rs:WP_015229361	DNA topoisomerase I [Dactylococcopsis salina].	22.80	535	346	13	77	572	67	573	4e-10	73.6
tr:A0A078AUV1_STYLE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.42	344	224	8	250	581	77	396	4e-10	73.2
rs:WP_022452649	DNA topoisomerase [Prevotella sp. CAG:873].	22.01	527	349	17	3	520	36	509	4e-10	73.6
rs:WP_001933720	DNA topoisomerase [Helicobacter pylori].	23.03	469	306	14	99	537	77	520	4e-10	73.2
rs:WP_001966173	DNA topoisomerase [Helicobacter pylori].	23.62	470	303	14	99	537	77	521	4e-10	73.2
rs:WP_043808620	DNA topoisomerase I [Rhodococcus triatomae].	23.68	587	339	21	2	530	21	556	4e-10	73.6
tr:M1JIJ8_ENCCN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AGE95214.1};	22.51	502	319	17	99	573	1	459	4e-10	73.2
sp:RGYR_PYRAB	RecName: Full=Reverse gyrase {ECO:0000255|HAMAP-Rule:MF_01125}; Includes: RecName: Full=Helicase {ECO:0000255|HAMAP-Rule:MF_01125}; EC=3.6.4.12 {ECO:0000255|HAMAP-Rule:MF_01125}; Includes: RecName: Full=Topoisomerase {ECO:0000255|HAMAP-Rule:MF_01125}; EC=5.99.1.3 {ECO:0000255|HAMAP-Rule:MF_01125};	24.67	454	246	16	162	584	826	1214	4e-10	73.9
rs:WP_025882636	DNA topoisomerase I [Porphyromonas uenonis].	22.33	533	341	16	3	520	7	481	4e-10	73.6
tr:K1Z8A5_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	23.27	434	267	15	226	630	31	427	4e-10	73.2
rs:WP_022430037	DNA topoisomerase [Prevotella stercorea CAG:629].	22.54	599	375	18	3	580	5	535	4e-10	73.6
rs:WP_000047285	DNA topoisomerase III [Bacillus cereus].	36.36	110	58	5	3	107	5	107	4e-10	68.6
rs:WP_009603934	DNA topoisomerase I [SAR116 cluster alpha proteobacterium HIMB100].	22.89	581	339	24	1	534	1	519	4e-10	73.6
rs:WP_023528066	DNA topoisomerase I [Streptomycetaceae bacterium MP113-05].	23.04	599	333	24	2	530	13	553	4e-10	73.6
rs:WP_017318697	DNA topoisomerase I [Mastigocladopsis repens].	21.28	625	389	18	3	574	4	578	4e-10	73.6
rs:WP_001958571	DNA topoisomerase [Helicobacter pylori].	23.29	468	307	13	99	537	77	521	4e-10	73.2
rs:WP_032448809	DNA topoisomerase III, partial [Klebsiella pneumoniae].	30.98	184	111	4	510	680	2	182	4e-10	70.1
rs:XP_012245759	PREDICTED: DNA topoisomerase 3-alpha-like isoform X1 [Bombus impatiens].	22.10	656	404	24	46	642	92	699	5e-10	73.6
tr:F4MZL4_YEREN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	27.27	363	213	12	74	409	86	424	5e-10	72.8
rs:WP_031631577	DNA topoisomerase I [Pseudomonas aeruginosa].	22.63	517	283	18	74	537	59	511	5e-10	73.2
rs:WP_029355145	DNA topoisomerase I [Bosea sp. 117].	21.82	692	418	30	1	629	1	632	5e-10	73.6
tr:E9I3T1_DAPPU	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EFX61349.1}; Flags: Fragment;	31.71	164	97	5	453	610	68	222	5e-10	70.1
rs:WP_027739698	DNA topoisomerase I [Streptomyces sp. CNT360].	22.89	603	332	22	2	530	13	556	5e-10	73.6
rs:XP_002307047	hypothetical protein POPTR_0005s06810g [Populus trichocarpa].	21.86	645	389	25	3	585	5	596	5e-10	73.6
rs:WP_001066143	DNA topoisomerase I [Helicobacter pylori].	24.28	523	329	19	103	583	73	570	5e-10	73.2
rs:XP_009033421	hypothetical protein AURANDRAFT_20044, partial [Aureococcus anophagefferens].	20.22	638	419	20	3	585	8	610	5e-10	73.2
rs:WP_022911217	DNA topoisomerase I [Aestuariimicrobium kwangyangense].	23.04	599	330	23	3	530	5	543	5e-10	73.6
tr:C0QU27_PERMH	RecName: Full=Reverse gyrase {ECO:0000256|HAMAP-Rule:MF_01125, ECO:0000256|RuleBase:RU004026};	23.08	611	363	22	3	581	611	1146	5e-10	73.6
rs:WP_020779392	DNA topoisomerase I [Leptospira kirschneri].	23.85	675	381	27	3	630	4	592	5e-10	73.2
rs:XP_011347623	PREDICTED: DNA topoisomerase 3-alpha [Cerapachys biroi].	21.60	639	412	26	46	634	58	657	5e-10	73.6
rs:WP_004024431	DNA topoisomerase I [Mycoplasma agalactiae].	20.61	660	427	23	2	630	4	597	5e-10	73.2
rs:WP_045935848	DNA topoisomerase I [Bifidobacterium asteroides].	23.06	633	370	28	2	571	6	584	5e-10	73.6
rs:WP_034063959	DNA topoisomerase I [Pseudomonas aeruginosa].	22.53	506	297	18	74	537	59	511	5e-10	73.2
tr:H0X7X3_OTOGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.44	468	291	16	188	619	239	670	5e-10	73.6
rs:WP_038821518	hypothetical protein [Pseudomonas syringae].	30.83	120	82	1	465	583	41	160	5e-10	70.1
tr:W4VN30_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE94541.1};	42.86	98	53	2	487	581	11	108	5e-10	69.3
rs:WP_033659029	hypothetical protein, partial [Enterococcus faecium].	30.43	115	68	3	3	110	34	143	5e-10	69.3
rs:WP_039764098	reverse gyrase [Caldicellulosiruptor sp. F32].	23.20	500	278	19	66	536	648	1070	5e-10	73.6
rs:WP_007001207	DNA topoisomerase I [Actinobaculum massiliense].	22.88	590	338	21	3	530	4	538	5e-10	73.6
rs:WP_041173293	DNA topoisomerase I [Clostridium botulinum].	25.42	657	374	29	3	616	5	588	5e-10	73.2
rs:WP_020603436	DNA topoisomerase I [Spirosoma spitsbergense].	27.05	329	215	9	74	392	51	364	5e-10	73.6
rs:WP_039085178	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	23	3	614	4	579	5e-10	73.2
rs:WP_000681510	DNA topoisomerase I [Helicobacter pylori].	23.36	642	396	24	3	614	4	579	5e-10	73.2
rs:WP_001937969	DNA topoisomerase [Helicobacter pylori].	23.75	522	333	17	103	583	73	570	5e-10	73.2
rs:WP_012100386	DNA topoisomerase I [Clostridium botulinum].	26.04	576	337	25	83	616	60	588	5e-10	73.2
rs:WP_023105002	DNA topoisomerase I [Pseudomonas aeruginosa].	22.24	517	285	18	74	537	59	511	5e-10	73.2
tr:G3NI54_GASAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	21.96	419	269	13	188	585	207	588	5e-10	73.6
tr:A0A078L6H7_9CHLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.48	565	351	19	98	614	75	600	5e-10	73.6
gp:CP004054_4499	DNA topoisomerase III [Pseudomonas aeruginosa PA1]	21.75	593	350	21	74	612	11	543	5e-10	73.2
rs:WP_030651823	DNA topoisomerase I [Streptomyces rimosus].	23.32	596	330	22	2	530	14	549	5e-10	73.6
rs:WP_001066137	DNA topoisomerase I [Helicobacter pylori].	23.56	522	334	16	103	583	73	570	5e-10	73.2
rs:WP_001889959	DNA topoisomerase I [Helicobacter pylori].	23.08	468	308	12	99	537	77	521	5e-10	73.2
rs:WP_008041237	topoisomerase I [Reinekea blandensis].	25.05	535	326	26	103	611	78	563	5e-10	73.2
rs:WP_017609913	DNA topoisomerase I [Nocardiopsis xinjiangensis].	22.00	591	343	21	3	530	25	560	5e-10	73.6
rs:WP_041948020	DNA topoisomerase I, partial [Truepera radiovictrix].	24.12	597	325	26	2	530	12	548	5e-10	73.2
rs:XP_002770630	DEHA2G13376p [Debaryomyces hansenii CBS767].	22.78	641	382	26	3	580	4	594	5e-10	73.2
rs:WP_034058858	DNA topoisomerase I [Pseudomonas aeruginosa].	21.85	563	346	20	90	614	65	571	5e-10	73.2
rs:WP_034406896	DNA topoisomerase I [Deinococcus sp. RL].	23.53	595	328	24	3	530	5	539	5e-10	73.6
rs:WP_033613109	DNA topoisomerase I [Helicobacter pylori].	23.35	471	303	13	99	537	77	521	5e-10	73.2
rs:WP_023026234	DNA topoisomerase I [Mesoplasma florum].	23.08	676	396	29	3	625	5	609	5e-10	73.2
tr:A0A086TI58_ACRCH	SubName: Full=DNA topoisomerase-like protein {ECO:0000313|EMBL:KFH49040.1};	22.48	565	345	24	3	520	4	522	5e-10	73.2
rs:WP_044103448	DNA topoisomerase I [Acinetobacter pittii].	21.31	582	378	23	76	611	55	602	5e-10	73.2
rs:WP_032849199	DNA topoisomerase III, partial [Mannheimia haemolytica].	31.01	129	82	1	486	614	7	128	5e-10	69.7
rs:WP_013908056	topoisomerase [Thermodesulfatator indicus].	23.66	524	308	21	72	565	672	1133	5e-10	73.6
rs:WP_023440369	DNA topoisomerase I [Pediococcus pentosaceus].	22.67	569	377	19	90	629	70	604	5e-10	73.2
rs:WP_022421259	DNA topoisomerase [Clostridium sp. CAG:307].	22.22	648	423	22	3	629	4	591	5e-10	73.2
rs:WP_034370861	DNA topoisomerase I [Dermabacter hominis].	22.19	658	376	24	3	585	6	602	5e-10	73.2
rs:WP_017563077	DNA topoisomerase I [Nocardiopsis synnemataformans].	21.83	591	344	18	3	530	25	560	5e-10	73.6
rs:WP_000309895	hypothetical protein, partial [Shigella boydii].	31.40	121	76	1	490	610	2	115	5e-10	69.3
rs:XP_007121076	PREDICTED: DNA topoisomerase 3-alpha [Physeter catodon].	22.43	486	304	17	188	634	93	544	5e-10	73.2
rs:WP_017746750	DNA topoisomerase I [Scytonema hofmanni].	22.94	606	346	22	79	610	59	617	5e-10	73.2
rs:WP_033582551	DNA topoisomerase I [Helicobacter pylori].	30.00	270	166	10	80	330	52	317	5e-10	73.2
tr:H2EAK3_9VIRU	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:AEX61426.1};	24.39	578	305	26	3	521	4	508	5e-10	73.2
tr:D7CT23_TRURR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.12	597	325	26	2	530	12	548	5e-10	73.6
rs:WP_042543808	DNA topoisomerase I [Leucobacter komagatae].	22.64	636	383	25	2	574	18	607	5e-10	73.2
rs:WP_001889982	DNA topoisomerase I [Helicobacter pylori].	23.08	468	308	12	99	537	77	521	5e-10	73.2
rs:WP_005890473	DNA topoisomerase I subunit omega, partial [Pseudomonas coronafaciens].	24.63	402	247	15	254	633	4	371	5e-10	72.8
rs:WP_004352838	DNA topoisomerase I [Pseudomonas aeruginosa].	23.06	503	298	17	74	537	59	511	5e-10	73.2
rs:WP_028127009	hypothetical protein [Entomoplasma lucivorax].	23.55	569	325	22	2	536	3	495	5e-10	73.2
tr:J7YWW8_BACCE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJQ19550.1};	31.84	179	112	5	510	680	1	177	5e-10	69.7
rs:XP_005536404	DNA topoisomerase I [Cyanidioschyzon merolae strain 10D].	22.39	518	308	16	77	524	205	698	5e-10	73.6
rs:WP_043487167	DNA topoisomerase I [Pseudomonas aeruginosa].	21.75	593	350	21	74	612	59	591	5e-10	73.2
rs:XP_008556751	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Microplitis demolitor].	23.10	554	338	21	46	560	103	607	5e-10	73.6
rs:WP_000681446	DNA topoisomerase I [Helicobacter pylori].	23.12	640	400	24	3	614	4	579	5e-10	73.2
tr:A0A0D0ITE6_9MICO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.64	636	383	25	2	574	4	593	5e-10	73.2
rs:WP_033936377	DNA topoisomerase I [Pseudomonas aeruginosa].	22.31	511	292	17	74	537	59	511	5e-10	72.8
rs:XP_008530670	PREDICTED: DNA topoisomerase 3-alpha [Equus przewalskii].	22.69	498	288	18	188	634	213	664	5e-10	73.2
rs:XP_009016694	hypothetical protein HELRODRAFT_99171 [Helobdella robusta].	22.53	586	361	25	3	537	5	548	6e-10	73.2
tr:W6LVX3_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.91	537	326	20	55	534	31	536	6e-10	73.2
rs:XP_010635743	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Fukomys damarensis].	22.58	465	294	15	188	619	239	670	6e-10	73.2
tr:J6CY98_PASMD	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJS91690.1}; Flags: Fragment;	31.87	160	105	3	353	511	1	157	6e-10	69.3
rs:WP_033991699	DNA topoisomerase I [Pseudomonas aeruginosa].	23.55	518	277	21	74	537	59	511	6e-10	72.8
rs:WP_004758353	DNA topoisomerase I [Leptospira kirschneri].	23.89	674	382	25	3	630	4	592	6e-10	72.8
tr:A0A0D7BWQ8_9HOMO	SubName: Full=Prokaryotic type I DNA topoisomerase {ECO:0000313|EMBL:KIY74081.1};	23.76	627	389	24	3	579	4	591	6e-10	73.2
rs:WP_031627730	DNA topoisomerase I [Pseudomonas sp. 2_1_26].	22.33	506	298	18	74	537	59	511	6e-10	72.8
rs:WP_012938598	DNA topoisomerase I, partial [Acidaminococcus fermentans].	23.17	561	356	21	90	616	67	586	6e-10	73.2
rs:XP_003033227	hypothetical protein SCHCODRAFT_54192 [Schizophyllum commune H4-8].	23.21	616	396	23	3	573	4	587	6e-10	72.8
tr:H6RXG4_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.66	534	337	18	3	521	5	477	6e-10	73.2
rs:WP_003842799	DNA topoisomerase I [Bifidobacterium dentium].	22.62	650	366	23	2	571	6	598	6e-10	73.2
rs:WP_043041427	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	21.51	581	378	23	76	611	55	602	6e-10	73.2
gp:D87012_1	topoisomerase-III [Homo sapiens]	22.64	645	386	29	3	585	5	598	6e-10	73.2
rs:WP_043153070	DNA topoisomerase I [Pseudomonas aeruginosa].	22.61	513	288	17	74	537	59	511	6e-10	72.8
rs:WP_016560414	DNA topoisomerase I [Leptospira kirschneri].	23.99	667	390	25	3	630	4	592	6e-10	72.8
rs:XP_001902741	DNA topoisomerase III [Brugia malayi].	21.60	551	378	17	46	573	6	525	6e-10	73.2
rs:WP_022579620	DNA topoisomerase I [Pseudomonas aeruginosa].	22.16	519	283	18	74	537	59	511	6e-10	72.8
rs:WP_013188968	DNA topoisomerase I [Mobiluncus curtisii].	21.98	655	362	22	2	571	7	597	6e-10	73.2
rs:XP_001804860	hypothetical protein SNOG_14677 [Phaeosphaeria nodorum SN15].	22.84	543	333	23	35	525	29	537	6e-10	72.8
rs:WP_004011329	DNA topoisomerase I [Mobiluncus curtisii].	21.98	655	362	22	2	571	7	597	6e-10	73.2
rs:WP_042288329	DNA topoisomerase I [Nonlabens ulvanivorans].	25.93	540	323	20	3	527	5	482	6e-10	73.2
tr:W1MU77_PSEAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	22.42	513	289	17	74	537	11	463	6e-10	72.8
rs:WP_013218143	DNA topoisomerase I [Dehalogenimonas lykanthroporepellens].	22.47	681	400	29	2	625	6	615	6e-10	72.8
rs:XP_008879533	hypothetical protein H310_13695 [Aphanomyces invadans].	23.16	613	376	24	3	560	4	576	6e-10	73.2
rs:WP_046456236	DNA topoisomerase I [Leucobacter sp. Ag1].	22.80	592	346	21	2	530	6	549	6e-10	73.2
rs:WP_012854854	DNA topoisomerase I [Thermomonospora curvata].	21.94	597	336	22	2	530	26	560	6e-10	73.2
rs:WP_015216772	DNA topoisomerase I [Anabaena cylindrica].	21.29	620	392	18	3	574	4	575	6e-10	73.2
tr:A0A068BCF9_COCNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.78	417	271	12	188	585	221	605	6e-10	73.2
rs:WP_034140206	DNA topoisomerase I [Desulfosporosinus sp. BICA1-9].	22.34	591	378	22	88	634	62	615	6e-10	72.8
rs:WP_016264249	DNA topoisomerase I [Pseudomonas aeruginosa].	22.63	517	283	19	74	537	59	511	6e-10	72.8
tr:W7JI63_PLAFA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EWC74513.1};	22.80	649	364	23	3	557	7	612	6e-10	72.8
tr:A0LWD4_ACIC1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.05	585	359	21	2	538	37	572	6e-10	73.2
rs:WP_034035504	DNA topoisomerase I [Pseudomonas aeruginosa].	22.93	519	281	20	74	537	59	513	6e-10	72.8
rs:XP_001586668	hypothetical protein SS1G_12655 [Sclerotinia sclerotiorum 1980 UF-70].	22.56	563	348	22	3	520	6	525	6e-10	72.8
rs:WP_001921627	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	6e-10	72.8
rs:WP_013604174	DNA topoisomerase [Vulcanisaeta moutnovskia].	21.68	429	286	9	188	590	203	607	6e-10	72.8
rs:XP_007939652	PREDICTED: DNA topoisomerase 3-alpha [Orycteropus afer afer].	23.49	464	285	17	188	616	239	667	6e-10	73.2
rs:WP_023101571	DNA topoisomerase I [Pseudomonas aeruginosa].	22.42	513	289	17	74	537	59	511	6e-10	72.8
tr:F3GKX3_PSESJ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGH47726.1}; Flags: Fragment;	31.65	139	90	2	89	223	2	139	6e-10	69.3
tr:A0A0D8XQF9_DICVI	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:KJH44606.1};	28.40	250	158	8	188	426	91	330	6e-10	71.6
rs:WP_000681482	DNA topoisomerase I [Helicobacter pylori].	22.69	648	393	24	3	614	4	579	6e-10	72.8
rs:WP_004783475	DNA topoisomerase I [Leptospira kirschneri].	23.77	673	384	24	3	630	4	592	6e-10	72.8
rs:WP_005028476	DNA topoisomerase I [Acinetobacter bereziniae].	22.32	587	366	25	76	611	55	602	6e-10	73.2
rs:WP_024655075	DNA topoisomerase I [Borrelia hispanica].	24.01	579	347	23	77	604	69	605	7e-10	73.2
rs:XP_007174215	PREDICTED: DNA topoisomerase 3-alpha [Balaenoptera acutorostrata scammoni].	23.08	494	291	18	188	634	239	690	7e-10	73.2
rs:WP_018029297	hypothetical protein [Porphyromonas somerae].	22.43	526	352	13	3	523	5	479	7e-10	72.8
rs:WP_033985421	DNA topoisomerase I [Pseudomonas aeruginosa].	22.66	503	300	16	74	537	59	511	7e-10	72.8
rs:WP_016198248	DNA topoisomerase I [Elizabethkingia meningoseptica].	24.39	410	236	12	3	392	5	360	7e-10	72.8
rs:WP_045107952	DNA topoisomerase I [Pseudomonas sp. HMSC05H02].	23.33	510	270	19	83	537	68	511	7e-10	72.8
rs:WP_023094336	DNA topoisomerase I [Pseudomonas aeruginosa].	22.24	517	285	18	74	537	59	511	7e-10	72.8
tr:W4I7S2_PLAFA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETW39467.1};	22.80	649	364	23	3	557	7	612	7e-10	72.8
rs:WP_017706951	hypothetical protein, partial [Pseudomonas syringae].	25.57	176	126	3	420	590	2	177	7e-10	69.7
rs:WP_014343771	DNA topoisomerase III [Aliivibrio fischeri].	31.65	139	86	3	486	620	8	141	7e-10	69.7
sp:TOP3A_ARATH	RecName: Full=DNA topoisomerase 3-alpha; EC=5.99.1.2;	21.94	638	397	25	3	585	12	603	7e-10	73.2
rs:WP_033866760	DNA topoisomerase I [Pseudomonas aeruginosa].	20.89	627	356	22	74	641	59	604	7e-10	72.8
rs:XP_010971510	PREDICTED: DNA topoisomerase 3-alpha [Camelus bactrianus].	23.22	491	294	18	188	634	182	633	7e-10	73.2
tr:A0A0B8NR71_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAM54802.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAM54802.1};	43.59	78	44	0	457	534	65	142	7e-10	68.9
rs:WP_024955483	DNA topoisomerase I [Sulfurospirillum arcachonense].	23.12	666	402	26	3	629	4	598	7e-10	72.8
rs:WP_033945040	DNA topoisomerase I [Pseudomonas aeruginosa].	23.79	517	277	21	74	537	59	511	7e-10	72.8
rs:WP_023102572	DNA topoisomerase I [Pseudomonas aeruginosa].	21.86	517	287	18	74	537	59	511	7e-10	72.8
rs:WP_020310043	MULTISPECIES: DNA topoisomerase [Megasphaera].	21.18	680	411	23	3	630	58	664	7e-10	72.8
rs:WP_004347969	DNA topoisomerase I [Pseudomonas aeruginosa].	22.93	519	281	20	74	537	59	513	7e-10	72.8
rs:WP_008380089	DNA topoisomerase I [Gordonia malaquae].	24.75	594	325	27	2	530	13	549	7e-10	73.2
rs:WP_025400131	DNA topoisomerase I [Borrelia hermsii].	23.36	548	328	20	77	577	69	571	7e-10	72.8
rs:WP_031840281	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	32.76	116	68	4	2	113	3	112	7e-10	69.3
rs:WP_033963813	DNA topoisomerase I [Pseudomonas aeruginosa].	22.07	512	292	18	74	537	59	511	7e-10	72.8
rs:WP_040726675	DNA topoisomerase I [Thiomicrospira sp. Kp2].	22.61	544	325	18	3	520	4	477	7e-10	72.8
rs:WP_000655364	DNA topoisomerase I [Helicobacter pylori].	27.90	276	175	10	75	330	46	317	7e-10	72.8
rs:WP_015511922	DNA topoisomerase I [Candidatus Mycoplasma haemominutum].	24.92	602	341	24	72	614	46	595	7e-10	72.8
rs:WP_004007690	DNA topoisomerase I [Mobiluncus curtisii].	21.98	655	362	22	2	571	7	597	7e-10	72.8
rs:XP_001614250	DNA topoisomerase III alpha [Plasmodium vivax Sal-1].	25.90	332	185	13	251	557	319	614	7e-10	72.8
rs:WP_004767943	DNA topoisomerase I [Leptospira kirschneri].	23.89	674	382	25	3	630	4	592	7e-10	72.4
rs:XP_012563421	PREDICTED: DNA topoisomerase 3-alpha-like [Hydra vulgaris].	22.06	671	424	27	3	616	12	640	7e-10	73.2
rs:WP_033174869	DNA topoisomerase I [Streptomyces sp. URHA0041].	23.01	604	328	24	2	530	13	554	7e-10	72.8
rs:WP_034435230	DNA topoisomerase I [Candidatus Contendobacter odensis].	22.91	537	326	20	55	534	29	534	7e-10	72.8
rs:WP_038312524	DNA topoisomerase I [bacterium YEK0313].	25.06	427	245	20	1	392	1	387	7e-10	72.8
rs:WP_023875927	DNA topoisomerase I [Pseudomonas aeruginosa].	22.53	506	297	18	74	537	59	511	7e-10	72.8
rs:WP_023119716	DNA topoisomerase I [Pseudomonas aeruginosa].	22.73	506	296	18	74	537	59	511	7e-10	72.8
rs:WP_024160721	topoisomerase I [Acinetobacter nosocomialis].	22.32	587	366	25	76	611	55	602	7e-10	72.8
rs:WP_032056289	DNA topoisomerase I [Acinetobacter baumannii].	21.69	581	377	24	76	611	55	602	7e-10	72.8
tr:A0A0C1NEQ2_9CYAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.22	603	383	16	3	560	4	565	7e-10	72.8
tr:K9D1Y5_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.98	587	392	19	83	636	30	583	7e-10	72.8
rs:WP_016860420	DNA topoisomerase I [Fischerella muscicola].	23.56	607	372	18	3	560	4	567	7e-10	72.8
tr:A0A078HPQ0_BRANA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.56	640	398	24	3	585	12	604	7e-10	72.8
rs:WP_042631886	DNA topoisomerase I [Helicobacter pylori].	22.97	640	401	24	3	614	4	579	7e-10	72.8
rs:WP_012914514	DNA topoisomerase I [Gardnerella vaginalis].	22.92	624	382	22	2	571	6	584	7e-10	72.8
rs:WP_042967119	DNA topoisomerase I [Helicobacter pylori].	24.04	470	301	14	99	537	77	521	7e-10	72.4
rs:WP_033593490	DNA topoisomerase I [Helicobacter pylori].	23.89	473	298	15	99	537	77	521	7e-10	72.4
rs:WP_001066152	DNA topoisomerase I [Helicobacter pylori].	23.75	522	333	17	103	583	73	570	7e-10	72.8
tr:T0XN89_9BACT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD24261.1}; Flags: Fragment;	34.19	117	68	5	1	113	1	112	7e-10	68.9
rs:WP_040161716	DNA topoisomerase I [Helicobacter pylori].	22.38	639	406	21	3	614	4	579	7e-10	72.8
rs:WP_016753194	DNA topoisomerase I [Leptospira kirschneri].	23.89	674	382	25	3	630	4	592	7e-10	72.4
rs:WP_046312892	DNA topoisomerase I [Pontibacter korlensis].	23.11	541	355	17	77	596	54	554	7e-10	72.8
rs:WP_015587161	DNA topoisomerase I [Mycoplasma putrefaciens].	25.14	346	178	11	3	314	4	302	7e-10	72.4
rs:WP_000277557	DNA topoisomerase I [Helicobacter pylori].	22.48	467	311	12	99	537	77	520	7e-10	72.4
rs:XP_012245760	PREDICTED: DNA topoisomerase 3-alpha-like isoform X2 [Bombus impatiens].	22.10	656	404	24	46	642	8	615	7e-10	72.8
tr:C7H3M5_9FIRM	SubName: Full=Topoisomerase DNA-binding C4 zinc finger domain protein {ECO:0000313|EMBL:EEU97459.1};	27.66	188	114	5	497	671	14	192	7e-10	69.7
tr:A0A0C9QZN0_9HYME	SubName: Full=Top3a_0 protein {ECO:0000313|EMBL:JAG70933.1}; SubName: Full=Top3a_1 protein {ECO:0000313|EMBL:JAG70932.1};	21.88	640	411	22	46	634	96	697	7e-10	72.8
rs:WP_008582879	DNA topoisomerase I [Niabella soli].	23.52	557	348	18	3	539	5	503	8e-10	72.8
sp:TOP3_SCHPO	RecName: Full=DNA topoisomerase 3; EC=5.99.1.2; AltName: Full=DNA topoisomerase III;	23.05	616	381	18	3	565	4	579	8e-10	72.4
rs:WP_034072159	DNA topoisomerase I [Pseudomonas aeruginosa].	21.86	517	287	18	74	537	59	511	8e-10	72.4
tr:J6QTA5_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EJX60843.1}; Flags: Fragment;	31.53	111	72	3	3	110	5	114	8e-10	68.2
rs:WP_041201379	DNA topoisomerase I [Helicobacter pylori].	23.29	468	307	12	99	537	77	521	8e-10	72.4
sp:TOP1_RICBR	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	22.68	679	425	24	1	630	1	628	8e-10	72.8
tr:B5Z818_HELPG	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:ACI27717.1};	23.29	468	307	12	99	537	36	480	8e-10	72.4
rs:WP_004777121	DNA topoisomerase I [Leptospira kirschneri].	23.77	673	384	24	3	630	4	592	8e-10	72.4
rs:XP_009188109	PREDICTED: DNA topoisomerase 3-alpha [Papio anubis].	22.83	460	291	14	188	619	239	662	8e-10	72.8
tr:I9UVG3_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	24.13	543	346	18	74	575	45	562	8e-10	72.4
tr:K1SJ22_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC47331.1}; Flags: Fragment;	26.04	265	163	7	258	510	2	245	8e-10	69.7
rs:XP_004669092	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Jaculus jaculus].	22.89	485	303	16	188	634	144	595	8e-10	72.8
rs:WP_000681500	DNA topoisomerase I [Helicobacter pylori].	22.97	640	401	24	3	614	4	579	8e-10	72.8
rs:WP_001884380	DNA topoisomerase I [Helicobacter pylori].	23.09	485	320	13	82	537	61	521	8e-10	72.4
tr:V7HYT0_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.74	575	376	18	90	629	40	575	8e-10	72.4
rs:WP_026429052	DNA topoisomerase I [Actinobaculum schaalii].	23.77	589	335	23	2	530	3	537	8e-10	72.8
rs:WP_020774334	DNA topoisomerase I [Leptospira alstonii].	24.47	666	391	29	3	630	4	595	8e-10	72.4
rs:WP_034038659	DNA topoisomerase I [Pseudomonas aeruginosa].	21.05	627	355	22	74	641	59	604	8e-10	72.4
gp:CP002222_1474	DNA topoisomerase I [Lactobacillus plantarum subsp. plantarum ST-III]	22.47	583	375	23	90	635	63	605	8e-10	72.4
rs:WP_042107570	DNA topoisomerase III, partial [Escherichia coli].	38.30	94	58	0	488	581	1	94	8e-10	68.6
rs:WP_001935327	DNA topoisomerase [Helicobacter pylori].	22.70	467	310	12	99	537	77	520	8e-10	72.4
rs:WP_009016940	DNA topoisomerase I [Parabacteroides sp. D13].	22.37	532	342	14	3	520	5	479	8e-10	72.8
rs:XP_002528003	prokaryotic DNA topoisomerase, putative [Ricinus communis].	22.61	522	320	19	64	536	332	818	8e-10	72.8
rs:WP_003690280	DNA topoisomerase I [Lactobacillus mali].	23.01	565	354	18	103	629	93	614	8e-10	72.4
rs:WP_038024337	DNA topoisomerase I [Synechococcus sp. RS9916].	22.90	620	378	21	3	572	5	574	8e-10	72.8
rs:WP_020088643	DNA topoisomerase I [Lactobacillus parabrevis].	23.03	595	364	25	88	635	78	625	8e-10	72.4
rs:WP_039053464	hypothetical protein [Sphingobacterium sp. T2].	31.58	190	123	7	492	676	15	202	8e-10	69.3
rs:XP_008556752	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Microplitis demolitor].	23.10	554	338	21	46	560	58	562	8e-10	72.8
rs:WP_023110927	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	22.57	514	289	19	74	537	59	513	8e-10	72.0
rs:WP_033584725	DNA topoisomerase I [Helicobacter pylori].	23.21	642	397	24	3	614	4	579	8e-10	72.4
tr:A0A0C3EM39_9HOMO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.15	596	381	22	3	552	4	562	8e-10	72.4
rs:WP_004511123	DNA topoisomerase I [Arcobacter butzleri].	23.62	563	344	22	3	533	4	512	8e-10	72.4
rs:XP_005808881	PREDICTED: DNA topoisomerase 3-alpha-like [Xiphophorus maculatus].	21.49	484	312	15	188	634	254	706	8e-10	72.8
tr:A0A076LI67_9EURY	RecName: Full=Reverse gyrase {ECO:0000256|HAMAP-Rule:MF_01125, ECO:0000256|RuleBase:RU004026};	23.64	516	313	17	82	576	658	1113	8e-10	72.8
rs:WP_042633510	DNA topoisomerase I [Helicobacter pylori].	22.70	467	310	13	99	537	77	520	9e-10	72.4
rs:WP_015085368	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	23	3	614	4	579	9e-10	72.4
rs:WP_040746384	DNA topoisomerase III, partial [alpha proteobacterium BAL199].	30.60	134	90	1	456	586	47	180	9e-10	71.2
rs:WP_011986801	DNA topoisomerase I [Clostridium botulinum].	25.27	657	375	28	3	616	9	592	9e-10	72.4
rs:WP_035779452	hypothetical protein [Clostridium butyricum].	32.00	150	94	5	527	673	1	145	9e-10	68.9
tr:A0A0C3CP21_HEBCY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.96	601	395	20	3	560	4	573	9e-10	72.4
tr:A0A093YXY7_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY09901.1};	22.11	570	364	21	3	532	6	535	9e-10	72.4
rs:WP_000681434	DNA topoisomerase I [Helicobacter pylori].	22.81	640	402	24	3	614	4	579	9e-10	72.4
rs:XP_009264369	DNA topoisomerase II [Encephalitozoon romaleae SJ-2008].	22.27	503	319	16	99	573	1	459	9e-10	72.4
rs:WP_022869417	DNA topoisomerase I [Yaniella halotolerans].	22.38	581	353	19	2	530	15	549	9e-10	72.8
rs:WP_001730851	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	23.42	363	231	12	290	633	1	335	9e-10	72.0
rs:WP_040881631	DNA topoisomerase I, partial [Janibacter hoylei].	23.01	578	350	23	2	530	4	535	9e-10	72.8
tr:A0A093Y038_PENMA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.40	567	343	22	3	528	7	517	9e-10	72.0
rs:WP_025401003	DNA topoisomerase I [Borrelia crocidurae].	24.91	582	338	25	77	604	69	605	9e-10	72.4
rs:WP_044426265	DNA topoisomerase I [Skermanella aerolata].	21.79	615	394	21	75	630	55	641	9e-10	72.8
rs:WP_021581684	DNA topoisomerase [Helicobacter pylori].	23.75	522	333	17	103	583	73	570	9e-10	72.4
tr:G1UZZ8_9DELT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGW42403.1};	29.20	113	74	2	2	113	4	111	9e-10	68.9
rs:WP_012047858	DNA topoisomerase I [Clostridium botulinum].	25.42	657	374	29	3	616	5	588	9e-10	72.4
rs:WP_001922728	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	23	3	614	4	579	9e-10	72.4
rs:WP_000681508	DNA topoisomerase I [Helicobacter pylori].	22.85	639	403	23	3	614	4	579	9e-10	72.4
rs:WP_013191215	DNA topoisomerase I [Trichormus azollae].	21.19	604	396	16	3	566	4	567	9e-10	72.4
rs:WP_010730456	DNA topoisomerase 1 [Enterococcus faecium].	26.09	571	347	27	103	635	81	614	9e-10	72.4
tr:J9FCG0_9SPIT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.53	428	259	18	185	585	721	1111	9e-10	72.8
rs:WP_040202472	DNA topoisomerase III, partial [Klebsiella pneumoniae].	26.50	283	140	10	456	673	2	281	9e-10	70.5
rs:WP_045799666	DNA topoisomerase I [Rickettsia bellii].	22.68	679	425	24	1	630	1	628	9e-10	72.4
rs:WP_000681497	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	9e-10	72.4
tr:K1DZM7_9MICO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.84	578	351	23	2	530	4	535	9e-10	72.8
tr:C4U3J9_YERAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.00	363	214	12	74	409	86	424	9e-10	72.0
rs:WP_000681403	DNA topoisomerase I [Helicobacter pylori].	22.98	644	396	25	3	614	4	579	9e-10	72.4
rs:WP_007079454	DNA topoisomerase I [Aeromicrobium marinum].	23.35	501	301	15	77	528	67	533	9e-10	72.4
rs:XP_008879534	hypothetical protein, variant [Aphanomyces invadans].	23.16	613	376	24	3	560	4	576	9e-10	72.4
rs:XP_004776596	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Mustela putorius furo].	21.46	480	316	15	188	634	239	690	9e-10	72.4
rs:WP_034026384	DNA topoisomerase I [Pseudomonas aeruginosa].	22.53	506	297	18	74	537	59	511	9e-10	72.4
rs:WP_023591798	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	9e-10	72.4
rs:WP_018038760	DNA topoisomerase I [alpha proteobacterium SCGC AB-629-G21].	22.70	696	402	30	1	629	1	627	9e-10	72.4
rs:WP_022479784	DNA topoisomerase I [Prevotella sp. CAG:891].	23.96	480	292	16	76	526	52	487	9e-10	72.4
rs:WP_011456281	DNA topoisomerase I [Jannaschia sp. CCS1].	22.78	417	259	16	1	392	1	379	9e-10	72.4
rs:WP_033752600	DNA topoisomerase I, partial [Helicobacter pylori].	30.20	255	157	9	80	317	52	302	9e-10	71.2
rs:WP_000681459	DNA topoisomerase I [Helicobacter pylori].	23.38	693	426	29	3	636	4	650	9e-10	72.4
rs:WP_000655371	DNA topoisomerase I [Helicobacter pylori].	29.80	255	158	8	80	317	52	302	9e-10	72.4
rs:WP_016918982	DNA topoisomerase I [Methylocystis parvus].	22.49	618	362	23	84	629	59	631	9e-10	72.4
rs:XP_003378587	DNA topoisomerase 3-beta-1 protein [Trichinella spiralis].	22.14	524	342	17	46	537	6	495	9e-10	72.4
rs:WP_044069817	DNA topoisomerase I [Pseudomonas aeruginosa].	22.63	517	283	19	74	537	59	511	9e-10	72.4
tr:K9G3X9_PEND1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.07	457	266	17	148	560	106	525	9e-10	72.0
rs:WP_000047324	DNA topoisomerase III [Bacillus cereus].	36.36	110	58	5	3	107	5	107	9e-10	67.8
rs:XP_008887269	DNA topoisomerase III beta-1, putative [Hammondia hammondi].	21.44	611	389	23	3	564	6	574	9e-10	72.4
rs:WP_033888407	DNA topoisomerase I [Gardnerella vaginalis].	22.38	621	389	18	2	571	6	584	9e-10	72.4
rs:XP_546656	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Canis lupus familiaris].	22.67	494	293	17	188	634	239	690	9e-10	72.4
rs:WP_033944334	DNA topoisomerase I [Pseudomonas aeruginosa].	21.24	598	323	22	1	537	1	511	9e-10	72.4
rs:WP_037563180	hypothetical protein [Spirochaeta sp. JC202].	22.32	672	419	23	3	629	1	614	9e-10	72.4
rs:WP_016443329	DNA topoisomerase I [Actinobaculum schaalii].	23.94	589	334	23	2	530	3	537	9e-10	72.4
tr:B7C992_9FIRM	SubName: Full=Topoisomerase DNA-binding C4 zinc finger domain protein {ECO:0000313|EMBL:EEC90669.1};	28.65	178	119	3	497	669	14	188	9e-10	69.3
tr:F9WNV5_TRYVY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	20.76	395	265	11	188	564	154	518	9e-10	72.0
rs:WP_042150501	DNA topoisomerase I [Streptomyces sp. NBRC 110027].	22.56	594	336	22	2	530	14	548	9e-10	72.4
rs:XP_004776594	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Mustela putorius furo].	21.46	480	316	15	188	634	239	690	9e-10	72.4
rs:XP_006963403	DNA topoisomerase [Trichoderma reesei QM6a].	22.68	560	350	22	3	520	4	522	1e-09	72.4
rs:WP_034064766	DNA topoisomerase I [Pseudomonas aeruginosa].	22.05	517	286	18	74	537	59	511	1e-09	72.0
rs:WP_001946283	DNA topoisomerase [Helicobacter pylori].	23.75	522	333	17	103	583	73	570	1e-09	72.4
rs:WP_003723893	DNA topoisomerase I, partial [Listeria monocytogenes].	24.37	398	270	12	105	480	82	470	1e-09	71.6
rs:WP_012579357	reverse gyrase [Thermosipho africanus].	24.39	529	295	20	28	534	534	979	1e-09	72.4
tr:T1GE59_MEGSC	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:MESCA001617-PA};	26.62	308	194	12	188	481	210	499	1e-09	72.0
rs:WP_014796302	DNA topoisomerase I [Flexibacter litoralis].	26.37	474	276	17	77	520	54	484	1e-09	72.4
rs:WP_045352264	DNA topoisomerase I [Lactobacillus plantarum].	22.47	583	375	23	90	635	95	637	1e-09	72.4
rs:WP_023129305	DNA topoisomerase I [Pseudomonas aeruginosa].	21.21	627	354	22	74	641	59	604	1e-09	72.0
rs:WP_013037299	DNA topoisomerase [Methanohalophilus mahii].	23.48	528	334	21	90	587	92	579	1e-09	72.4
rs:WP_001980592	DNA topoisomerase [Helicobacter pylori].	23.75	522	333	17	103	583	73	570	1e-09	72.4
rs:WP_006511007	DNA topoisomerase I [Xenococcus sp. PCC 7305].	22.82	539	345	17	77	574	67	575	1e-09	72.4
tr:Q05WM0_9SYNE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.90	620	378	21	3	572	20	589	1e-09	72.4
rs:WP_000681431	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	1e-09	72.4
rs:WP_001895970	DNA topoisomerase I [Helicobacter pylori].	22.86	468	309	12	99	537	77	521	1e-09	72.0
rs:WP_015645546	DNA topoisomerase I [Helicobacter pylori].	22.38	639	406	22	3	614	4	579	1e-09	72.4
gp:CP004146_894	DNA topoisomerase I [Borrelia hermsii YOR]	23.36	548	328	20	77	577	69	571	1e-09	72.0
rs:WP_014696639	DNA topoisomerase I [Borrelia crocidurae].	24.91	582	338	25	77	604	69	605	1e-09	72.4
rs:WP_000655252	DNA topoisomerase I [Helicobacter pylori].	23.49	545	350	18	80	583	52	570	1e-09	72.0
rs:XP_003496375	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Cricetulus griseus].	21.40	486	309	17	188	634	239	690	1e-09	72.4
rs:WP_046039372	DNA topoisomerase I [Lactobacillus plantarum].	22.47	583	375	23	90	635	95	637	1e-09	72.4
rs:WP_033339212	DNA topoisomerase I [Catenuloplanes japonicus].	21.93	652	357	26	2	571	9	590	1e-09	72.4
rs:WP_045740525	DNA topoisomerase I [Actinoplanes rectilineatus].	23.34	634	370	24	2	571	9	590	1e-09	72.4
rs:XP_007647342	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Cricetulus griseus].	21.40	486	309	17	188	634	238	689	1e-09	72.4
rs:WP_002205822	DNA topoisomerase I [Helicobacter pylori].	23.08	468	308	12	99	537	77	521	1e-09	72.0
rs:WP_047163065	hypothetical protein, partial [Trichodesmium erythraeum].	41.94	93	52	2	460	551	22	113	1e-09	67.8
tr:Q07L73_RHOP5	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.03	686	417	30	1	629	26	657	1e-09	72.4
rs:WP_019496473	hypothetical protein [Calothrix sp. PCC 7103].	25.14	537	303	23	90	575	74	562	1e-09	72.0
rs:XP_009235101	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Pongo abelii].	22.81	342	221	10	256	585	165	475	1e-09	72.4
tr:E6YLX8_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.80	693	411	29	1	629	1	633	1e-09	72.4
rs:XP_003868447	Top3 protein [Candida orthopsilosis Co 90-125].	21.85	627	391	18	3	574	4	586	1e-09	72.0
rs:WP_025020460	DNA topoisomerase I [Lactobacillus equi].	21.74	575	376	18	90	629	60	595	1e-09	72.0
rs:WP_041800896	DNA topoisomerase I [Rhodopseudomonas palustris].	23.00	687	418	30	1	630	1	633	1e-09	72.4
tr:A0A0B1P459_UNCNE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.41	508	312	22	46	520	6	474	1e-09	72.0
rs:WP_030801500	DNA topoisomerase I [Streptomyces sp. NRRL S-337].	22.86	595	334	22	2	530	14	549	1e-09	72.4
rs:XP_011306985	PREDICTED: DNA topoisomerase 3-alpha [Fopius arisanus].	22.26	647	400	24	46	634	96	697	1e-09	72.4
rs:WP_029567813	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	1e-09	72.0
rs:WP_001944292	DNA topoisomerase [Helicobacter pylori].	23.75	522	333	17	103	583	73	570	1e-09	72.0
rs:XP_006774025	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Myotis davidii].	22.83	495	285	18	188	631	188	636	1e-09	72.4
tr:D1KCD6_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.66	328	209	11	74	392	50	361	1e-09	72.4
rs:WP_013023049	DNA topoisomerase I [Helicobacter mustelae].	23.49	562	347	23	90	616	67	580	1e-09	72.0
tr:A0A095BWB6_SCHHA	SubName: Full=DNA topoisomerase 3-alpha {ECO:0000313|EMBL:KGB33288.1};	24.59	423	259	13	188	577	80	475	1e-09	72.4
rs:WP_037785772	DNA topoisomerase I [Streptomyces sp. CNT318].	23.20	612	327	23	2	530	13	564	1e-09	72.4
rs:XP_012321902	PREDICTED: DNA topoisomerase 3-beta-1 isoform X4 [Aotus nancymaae].	22.65	340	224	9	256	585	165	475	1e-09	72.0
tr:D0U4M2_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.66	328	209	11	74	392	50	361	1e-09	72.0
tr:X8JDB7_9HOMO	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EUC61727.1};	22.66	640	392	26	3	585	4	597	1e-09	72.4
rs:XP_003588645	DNA topoisomerase, partial [Medicago truncatula].	26.85	257	154	10	64	297	301	546	1e-09	71.6
rs:XP_002259878	DNA topoisomerase III [Plasmodium knowlesi strain H].	26.36	330	186	12	251	557	314	609	1e-09	72.0
rs:WP_001066134	DNA topoisomerase I [Helicobacter pylori].	23.75	522	333	17	103	583	73	570	1e-09	72.0
rs:WP_014061723	DNA topoisomerase I [Streptomyces violaceusniger].	22.74	598	331	23	2	530	14	549	1e-09	72.4
rs:WP_015720878	DNA topoisomerase I [Geobacter sp. M18].	23.39	637	357	25	76	630	53	640	1e-09	72.0
rs:WP_021627476	DNA topoisomerase I [Capnocytophaga sp. oral taxon 863].	25.05	531	328	18	3	521	5	477	1e-09	72.4
rs:WP_003644423	DNA topoisomerase I [Lactobacillus plantarum].	22.47	583	375	23	90	635	95	637	1e-09	72.0
rs:XP_004433056	PREDICTED: DNA topoisomerase 3-alpha [Ceratotherium simum simum].	22.57	483	307	15	188	634	239	690	1e-09	72.4
tr:A0A094DUA8_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY69864.1};	21.65	568	369	21	3	532	6	535	1e-09	72.0
rs:XP_005840332	hypothetical protein GUITHDRAFT_64354, partial [Guillardia theta CCMP2712].	23.69	591	331	26	3	530	1	534	1e-09	72.4
tr:A0A0A7RQ49_9THEM	RecName: Full=Reverse gyrase {ECO:0000256|HAMAP-Rule:MF_01125, ECO:0000256|RuleBase:RU004026};	22.95	475	275	17	81	533	642	1047	1e-09	72.4
rs:XP_001930451	DNA topoisomerase 3-beta [Pyrenophora tritici-repentis Pt-1C-BFP].	21.79	569	352	19	3	520	5	531	1e-09	72.0
rs:WP_039091272	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	1e-09	72.0
tr:A0A087GDY2_ARAAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.65	642	397	24	3	585	12	606	1e-09	72.4
rs:WP_035005899	DNA topoisomerase I [Bartonella rochalimae].	22.80	693	411	29	1	629	1	633	1e-09	72.0
rs:WP_000681493	DNA topoisomerase I [Helicobacter pylori].	22.46	650	392	23	3	614	4	579	1e-09	72.0
rs:XP_007617063	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Cricetulus griseus].	21.28	484	312	15	188	634	239	690	1e-09	72.4
rs:WP_000277573	DNA topoisomerase I [Helicobacter pylori].	23.16	475	298	12	99	537	77	520	1e-09	72.0
rs:WP_012781804	DNA topoisomerase I [Flavobacteriaceae bacterium 3519-10].	25.37	402	242	14	3	392	5	360	1e-09	72.0
rs:WP_000681458	DNA topoisomerase I [Helicobacter pylori].	23.38	693	426	29	3	636	4	650	1e-09	72.0
tr:K1YFN4_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.54	463	302	13	76	520	53	481	1e-09	71.6
rs:WP_029149405	DNA topoisomerase I [Microbacterium indicum].	23.30	515	307	16	77	538	68	547	1e-09	72.4
rs:XP_012321901	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Aotus nancymaae].	22.65	340	224	9	256	585	166	476	1e-09	72.0
rs:WP_000681445	DNA topoisomerase I [Helicobacter pylori].	23.48	643	394	26	3	614	4	579	1e-09	72.0
rs:WP_023124573	DNA topoisomerase I [Pseudomonas aeruginosa].	21.37	627	353	23	74	641	59	604	1e-09	72.0
rs:WP_030359673	MULTISPECIES: DNA topoisomerase I [Streptomyces].	22.69	595	334	21	2	530	13	547	1e-09	72.0
tr:V8EN21_PSEAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	21.53	627	352	23	74	641	11	556	1e-09	71.6
rs:WP_014659990	DNA topoisomerase I [Helicobacter cetorum].	22.87	529	357	14	82	578	54	563	1e-09	72.0
rs:WP_045797271	DNA topoisomerase I [Orientia chuto].	22.39	728	430	28	1	660	1	661	1e-09	72.0
tr:A0A080ZA53_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETO63514.1};	26.37	402	236	16	186	560	157	525	1e-09	72.0
rs:WP_005867659	DNA topoisomerase I [Parabacteroides sp. CAG:2].	22.66	534	338	16	3	520	29	503	1e-09	72.0
tr:Q8GE07_HELMO	RecName: Full=DNA topoisomerase I, plasmid {ECO:0000256|SAAS:SAAS00003555}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	23.30	455	286	14	90	514	71	492	1e-09	71.6
rs:WP_044430780	DNA topoisomerase I [Lactobacillus plantarum].	22.47	583	375	23	90	635	95	637	1e-09	72.0
rs:WP_031277332	DNA topoisomerase I [Pseudomonas aeruginosa].	21.53	627	352	23	74	641	59	604	1e-09	72.0
tr:A0A0C3QJC6_9HOMO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.54	628	426	19	3	586	4	602	1e-09	71.6
rs:WP_006330915	DNA topoisomerase I [Gordonia rhizosphera].	24.49	592	333	24	2	530	17	557	1e-09	72.0
rs:WP_017601719	DNA topoisomerase I [Nocardiopsis lucentensis].	22.01	586	343	18	3	530	25	554	1e-09	72.0
tr:M2RFS6_CERS8	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.24	634	397	25	3	584	54	643	1e-09	72.0
rs:WP_001066141	DNA topoisomerase I [Helicobacter pylori].	23.75	522	333	17	103	583	73	570	1e-09	72.0
tr:U3CUM4_CALJA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.11	489	297	17	188	634	239	690	1e-09	72.0
tr:H3G7Y5_PHYRM	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblProtists:Phyra54032}; Flags: Fragment;	23.79	454	279	14	188	608	208	627	1e-09	71.6
tr:J9FZL6_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central domain protein {ECO:0000313|EMBL:EJX00432.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EJX00432.1}; Flags: Fragment;	31.37	153	98	2	467	619	83	228	1e-09	69.3
rs:WP_033763301	DNA topoisomerase I [Helicobacter pylori].	23.35	544	353	16	80	583	52	571	1e-09	72.0
rs:WP_007074177	DNA topoisomerase I [Micromonospora sp. ATCC 39149].	22.45	637	372	25	2	571	9	590	1e-09	72.0
tr:W2YEZ5_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETP32749.1};	26.37	402	236	16	186	560	157	525	1e-09	72.0
rs:WP_040236860	DNA topoisomerase I [Borrelia crocidurae].	24.91	582	338	25	77	604	69	605	1e-09	72.0
rs:WP_007156365	DNA topoisomerase I [Oribacterium sinus].	22.10	647	408	23	3	616	5	588	1e-09	72.0
rs:WP_038519001	DNA topoisomerase I [Moraxella catarrhalis].	22.89	485	283	17	187	629	207	642	1e-09	72.0
rs:WP_001066155	DNA topoisomerase I [Helicobacter pylori].	23.87	465	294	15	157	583	128	570	1e-09	72.0
rs:WP_024421569	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	1e-09	72.0
rs:WP_044109241	DNA topoisomerase I [Acinetobacter sp. MII].	22.32	587	366	25	76	611	55	602	1e-09	72.0
rs:WP_002345057	DNA topoisomerase 1 [Enterococcus faecium].	25.70	572	348	26	103	635	81	614	1e-09	72.0
rs:XP_008913564	hypothetical protein, variant [Phytophthora parasitica INRA-310].	26.37	402	236	16	186	560	157	525	1e-09	72.0
tr:U3DN79_CALJA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.11	489	297	17	188	634	239	690	1e-09	72.0
rs:WP_036086741	DNA topoisomerase I [Leptospira weilii].	24.10	664	397	27	3	630	4	596	1e-09	71.6
rs:WP_003120981	DNA topoisomerase I [Pseudomonas aeruginosa].	22.14	515	288	18	74	537	59	511	1e-09	71.6
rs:XP_008994684	PREDICTED: DNA topoisomerase 3-alpha [Callithrix jacchus].	23.11	489	297	17	188	634	239	690	1e-09	72.0
rs:XP_010257889	PREDICTED: DNA topoisomerase 3-alpha [Nelumbo nucifera].	20.70	599	404	18	64	610	450	1029	1e-09	72.0
rs:XP_006774024	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Myotis davidii].	22.81	491	290	17	188	631	239	687	1e-09	72.0
rs:WP_042166570	DNA topoisomerase I [Pseudomonas aeruginosa].	22.33	506	298	18	74	537	59	511	1e-09	71.6
rs:XP_011144135	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Harpegnathos saltator].	21.91	648	400	26	46	634	105	705	1e-09	72.0
tr:S7PHJ6_MYOBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.01	491	289	17	188	631	214	662	1e-09	72.0
rs:WP_003645027	DNA topoisomerase [Lactobacillus plantarum].	22.47	583	375	23	90	635	95	637	1e-09	72.0
rs:WP_037969390	DNA topoisomerase I [Streptosporangium amethystogenes].	22.40	634	376	24	32	591	14	605	1e-09	72.0
rs:WP_033758945	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	1e-09	72.0
rs:WP_033622635	DNA topoisomerase I [Helicobacter pylori].	24.04	470	301	14	99	537	77	521	1e-09	71.6
rs:WP_016868573	DNA topoisomerase I [Fischerella muscicola].	23.10	619	368	19	3	564	4	571	1e-09	72.0
rs:WP_024160892	MULTISPECIES: topoisomerase I [Acinetobacter].	22.32	587	366	25	76	611	55	602	1e-09	72.0
rs:XP_008413798	PREDICTED: DNA topoisomerase 3-alpha [Poecilia reticulata].	22.86	468	290	16	188	619	250	682	1e-09	72.0
rs:WP_002327967	DNA topoisomerase 1 [Enterococcus faecium].	25.70	572	348	26	103	635	81	614	1e-09	71.6
rs:WP_002309561	DNA topoisomerase I [Enterococcus faecium].	25.70	572	348	26	103	635	81	614	1e-09	71.6
rs:WP_021301019	DNA topoisomerase I [Helicobacter pylori].	23.51	536	343	17	80	574	52	561	1e-09	71.6
rs:WP_000681505	DNA topoisomerase I [Helicobacter pylori].	22.81	640	402	24	3	614	4	579	1e-09	72.0
rs:WP_000681441	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	1e-09	72.0
rs:WP_023104007	DNA topoisomerase I [Pseudomonas aeruginosa].	22.24	517	285	18	74	537	59	511	1e-09	71.6
rs:WP_001066139	DNA topoisomerase I [Helicobacter pylori].	23.75	522	333	17	103	583	73	570	1e-09	71.6
rs:WP_001974508	DNA topoisomerase [Helicobacter pylori].	22.48	467	311	12	99	537	77	520	1e-09	71.6
rs:WP_034029993	DNA topoisomerase I [Pseudomonas aeruginosa].	22.24	517	285	18	74	537	59	511	1e-09	71.6
rs:WP_041560585	DNA topoisomerase I, partial [Nocardia farcinica].	22.92	602	331	22	2	530	17	558	1e-09	72.0
rs:WP_034352732	DNA topoisomerase I [Deinococcus phoenicis].	23.18	591	337	23	3	530	5	541	1e-09	72.0
rs:WP_002161842	DNA topoisomerase 1 [Bacillus cereus].	32.48	157	100	4	65	217	4	158	1e-09	68.2
rs:WP_033987969	DNA topoisomerase I [Pseudomonas aeruginosa].	22.05	517	286	18	74	537	59	511	1e-09	71.6
rs:WP_010732770	DNA topoisomerase 1 [Enterococcus faecium].	25.70	572	348	26	103	635	81	614	1e-09	71.6
rs:WP_001066150	DNA topoisomerase I [Helicobacter pylori].	23.87	465	294	15	157	583	128	570	1e-09	71.6
rs:WP_000655369	DNA topoisomerase I [Helicobacter pylori].	29.80	255	158	8	80	317	52	302	1e-09	71.6
rs:XP_005620201	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Canis lupus familiaris].	22.67	494	293	17	188	634	219	670	1e-09	72.0
tr:E2BS26_HARSA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.69	639	406	28	46	634	58	658	1e-09	72.0
rs:WP_028277717	DNA topoisomerase I [Arthrobacter sp. I3].	22.20	590	359	20	2	538	10	552	1e-09	72.0
rs:WP_005051207	DNA topoisomerase I [Microbacterium laevaniformans].	23.35	501	293	18	90	538	87	548	1e-09	72.0
rs:WP_024116083	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	1e-09	71.6
rs:WP_002331854	DNA topoisomerase 1 [Enterococcus faecium].	25.70	572	348	26	103	635	81	614	1e-09	71.6
rs:WP_033963406	DNA topoisomerase I [Pseudomonas aeruginosa].	22.24	517	285	18	74	537	59	511	1e-09	71.6
rs:XP_007617064	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Cricetulus griseus].	21.93	488	304	16	188	634	238	689	1e-09	72.0
rs:WP_038501935	DNA topoisomerase I [Rhodoluna lacicola].	22.47	592	336	23	2	528	6	539	1e-09	72.0
rs:WP_002298115	DNA topoisomerase I [Enterococcus faecium].	25.70	572	348	26	103	635	81	614	1e-09	71.6
rs:WP_034036278	DNA topoisomerase I [Pseudomonas aeruginosa].	21.05	627	355	22	74	641	59	604	1e-09	71.6
tr:A0A0B5H342_9THEM	RecName: Full=Reverse gyrase {ECO:0000256|HAMAP-Rule:MF_01125, ECO:0000256|RuleBase:RU004026};	22.95	475	275	17	81	533	644	1049	1e-09	72.0
rs:WP_044362462	DNA topoisomerase I [Streptomyces natalensis].	22.86	595	334	22	2	530	14	549	1e-09	72.0
rs:WP_029957349	hypothetical protein, partial [Acetothermia bacterium SCGC AAA255-C06].	22.87	704	435	24	2	666	5	639	1e-09	71.6
rs:WP_033768917	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	1e-09	71.6
rs:WP_021174553	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	23	3	614	4	579	1e-09	71.6
rs:WP_019873940	hypothetical protein [Sporichthya polymorpha].	22.01	636	376	21	3	571	17	599	1e-09	72.0
rs:WP_024948064	DNA topoisomerase I [Helicobacter pylori].	23.02	643	397	25	3	614	4	579	1e-09	71.6
rs:WP_012980123	reverse gyrase [Methanocaldococcus sp. FS406-22].	23.45	516	314	16	82	576	658	1113	1e-09	72.0
rs:WP_034031775	DNA topoisomerase I [Pseudomonas aeruginosa].	22.24	517	285	18	74	537	59	511	1e-09	71.6
rs:WP_024947298	DNA topoisomerase I [Pseudomonas aeruginosa].	23.39	513	284	20	74	537	59	511	1e-09	71.6
rs:WP_001932462	DNA topoisomerase [Helicobacter pylori].	23.87	465	294	15	157	583	128	570	1e-09	71.6
rs:WP_001066153	DNA topoisomerase I [Helicobacter pylori].	23.75	522	333	17	103	583	73	570	1e-09	71.6
rs:XP_012177953	predicted protein [Fibroporia radiculosa].	22.61	628	404	23	3	587	4	592	1e-09	72.0
tr:Q5Z2Y2_NOCFA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.92	602	331	22	2	530	21	562	1e-09	72.0
rs:XP_006048918	PREDICTED: DNA topoisomerase 3-alpha [Bubalus bubalis].	22.87	494	291	18	188	634	239	689	1e-09	72.0
rs:WP_036925130	hypothetical protein, partial [Prevotella veroralis].	34.56	136	76	4	54	178	1	134	1e-09	68.2
rs:WP_004118458	DNA topoisomerase I [Gardnerella vaginalis].	22.92	624	382	22	2	571	6	584	1e-09	72.0
rs:WP_004104755	DNA topoisomerase I [Gardnerella vaginalis].	22.92	624	382	22	2	571	6	584	1e-09	72.0
tr:A0A0D3AYL4_BRAOL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Bo2g165940.1};	21.82	637	400	24	3	585	12	604	1e-09	72.0
rs:WP_001066136	DNA topoisomerase I [Helicobacter pylori].	23.75	522	333	17	103	583	73	570	1e-09	71.6
tr:A0A0A7U047_LACBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.51	595	373	23	88	635	79	626	1e-09	71.6
rs:WP_027452456	DNA topoisomerase I [Prevotella albensis].	23.09	459	294	15	157	593	131	552	1e-09	71.6
rs:WP_033794371	DNA topoisomerase I [Helicobacter pylori].	23.83	470	302	14	99	537	77	521	1e-09	71.6
rs:XP_007617065	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Cricetulus griseus].	22.04	490	301	18	188	634	214	665	1e-09	72.0
rs:WP_033978938	DNA topoisomerase I [Pseudomonas aeruginosa].	21.86	517	287	18	74	537	59	511	1e-09	71.6
rs:WP_027748357	DNA topoisomerase I [Streptomyces sp. CNH287].	23.41	598	331	24	2	530	13	552	1e-09	72.0
sp:TOP1_RICFE	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	21.95	697	406	28	1	629	1	627	2e-09	71.6
rs:WP_001694606	DNA topoisomerase, partial [Escherichia coli].	30.77	182	113	4	501	676	1	175	2e-09	68.6
rs:WP_036876504	hypothetical protein, partial [Prauserella rugosa].	22.91	585	348	19	2	530	19	556	2e-09	72.0
tr:M3ZNA2_XIPMA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.98	464	299	14	188	619	254	686	2e-09	72.0
rs:WP_018234300	hypothetical protein [Thioalkalivibrio thiocyanodenitrificans].	29.53	193	123	4	445	631	17	202	2e-09	68.9
rs:WP_024568243	DNA topoisomerase I [Elizabethkingia anophelis].	25.13	398	248	14	3	392	5	360	2e-09	71.6
tr:A0A0C1P0E7_9PSEU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.91	585	348	19	2	530	19	556	2e-09	72.0
tr:S9WIL7_9TRYP	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EPY35740.1};	24.35	575	337	22	81	585	116	662	2e-09	71.6
rs:WP_002313870	DNA topoisomerase I [Enterococcus faecium].	25.70	572	348	26	103	635	81	614	2e-09	71.6
rs:WP_002290218	DNA topoisomerase I [Enterococcus faecium].	25.70	572	348	26	103	635	81	614	2e-09	71.6
rs:WP_033106624	DNA topoisomerase I [Microbacterium profundi].	23.31	605	328	25	2	538	6	542	2e-09	72.0
sp:TOP3_DICDI	RecName: Full=DNA topoisomerase 3; EC=5.99.1.2; AltName: Full=DNA topoisomerase III;	22.53	546	317	17	79	560	92	595	2e-09	71.6
rs:WP_000681437	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	23	3	614	4	579	2e-09	71.6
tr:W7CHH1_9LIST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	22.47	396	259	15	263	635	32	402	2e-09	71.2
rs:WP_001939808	DNA topoisomerase [Helicobacter pylori].	23.87	465	294	15	157	583	128	570	2e-09	71.6
rs:WP_000655379	DNA topoisomerase I [Helicobacter pylori].	23.49	545	350	19	80	583	52	570	2e-09	71.6
rs:WP_039504052	hypothetical protein, partial [Prauserella sp. Am3].	22.91	585	348	19	2	530	19	556	2e-09	72.0
rs:WP_019557205	DNA topoisomerase I [Thiomicrospira arctica].	22.14	533	341	17	3	520	4	477	2e-09	71.6
rs:WP_029406632	DNA topoisomerase I [Thiomicrospira sp. Milos-T2].	22.78	540	329	18	3	520	4	477	2e-09	71.6
tr:B3VT77_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.80	255	158	8	80	317	52	302	2e-09	71.6
rs:XP_004776595	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Mustela putorius furo].	21.46	480	316	15	188	634	239	690	2e-09	72.0
tr:M3P5G9_HELPX	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EMH35694.1};	23.87	465	294	15	157	583	68	510	2e-09	71.6
rs:WP_001977386	DNA topoisomerase [Helicobacter pylori].	23.87	465	294	15	157	583	128	570	2e-09	71.6
rs:WP_014791168	DNA topoisomerase I [Ornithobacterium rhinotracheale].	23.30	528	346	17	3	521	5	482	2e-09	71.6
rs:WP_016622928	hypothetical protein, partial [Enterococcus faecalis].	25.29	170	124	1	347	513	12	181	2e-09	68.2
tr:A0A0C2M7A6_9CYAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.81	518	334	13	100	574	90	579	2e-09	71.6
tr:S9YRU2_9CETA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.67	344	219	11	256	585	345	655	2e-09	72.0
rs:WP_033946933	DNA topoisomerase I [Pseudomonas aeruginosa].	22.24	517	285	18	74	537	59	511	2e-09	71.6
rs:XP_010841206	PREDICTED: DNA topoisomerase 3-alpha [Bison bison bison].	22.87	494	291	18	188	634	239	689	2e-09	72.0
rs:WP_035991054	DNA topoisomerase I [Leptolyngbya sp. KIOST-1].	22.40	616	372	19	3	565	4	566	2e-09	71.6
rs:WP_041488845	DNA topoisomerase I, partial [Bacillus mycoides].	35.77	137	84	3	103	236	1	136	2e-09	67.4
rs:WP_000655368	DNA topoisomerase I [Helicobacter pylori].	29.80	255	158	8	80	317	52	302	2e-09	71.6
tr:A0A086K1Q5_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.85	681	428	25	3	631	6	627	2e-09	71.6
rs:XP_005652066	prokaryotic type I DNA topoisomerase [Coccomyxa subellipsoidea C-169].	21.08	498	307	16	188	634	215	677	2e-09	71.6
rs:WP_001916775	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	23	3	614	4	579	2e-09	71.6
rs:WP_029485243	DNA topoisomerase I [Enterococcus faecium].	25.70	572	348	26	103	635	81	614	2e-09	71.6
tr:K7T463_9NEIS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	21.90	548	341	19	3	517	5	498	2e-09	71.2
rs:WP_001066149	DNA topoisomerase I [Helicobacter pylori].	23.87	465	294	15	157	583	128	570	2e-09	71.6
tr:A0A086LNK0_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.44	611	389	23	3	564	6	574	2e-09	71.6
rs:WP_031694571	DNA topoisomerase I, partial [Listeria monocytogenes].	22.56	390	252	14	263	629	2	364	2e-09	70.9
rs:WP_017311325	DNA topoisomerase I [Fischerella sp. PCC 9339].	23.00	639	360	20	3	572	4	579	2e-09	71.6
rs:WP_025324779	DNA topoisomerase I [Pseudomonas aeruginosa].	22.24	517	285	18	74	537	59	511	2e-09	71.2
rs:WP_022801505	DNA topoisomerase I [Deinococcus sp. 2009].	22.48	605	320	24	3	530	5	537	2e-09	71.6
rs:WP_029945924	DNA topoisomerase I, partial [Aminicenantes bacterium SCGC AAA252-P19].	23.04	473	301	16	187	629	76	515	2e-09	71.2
rs:XP_007647350	PREDICTED: DNA topoisomerase 3-alpha isoform X4 [Cricetulus griseus].	21.40	486	309	17	188	634	162	613	2e-09	71.6
rs:WP_024626956	DNA topoisomerase I [Bifidobacterium sp. A11].	23.85	633	365	25	2	571	6	584	2e-09	71.6
rs:WP_024114980	DNA topoisomerase I [Helicobacter pylori].	22.86	643	398	25	3	614	4	579	2e-09	71.6
tr:W2MF57_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETM34940.1};	26.69	356	206	14	186	519	157	479	2e-09	71.6
rs:WP_031646389	DNA topoisomerase I, partial [Listeria monocytogenes].	22.28	395	257	14	258	629	4	371	2e-09	70.9
rs:WP_028700188	DNA topoisomerase I [Pseudomonas monteilii].	23.83	470	307	13	84	533	69	507	2e-09	71.2
rs:WP_000681474	DNA topoisomerase I [Helicobacter pylori].	22.54	639	405	21	3	614	4	579	2e-09	71.6
rs:WP_007351674	DNA topoisomerase I [Marinobacter sp. ELB17].	22.73	638	399	23	3	615	5	573	2e-09	71.6
tr:A0A0E0CKE7_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OMERI02G16280.6};	22.72	559	331	22	39	541	310	823	2e-09	71.6
rs:WP_010727828	DNA topoisomerase 1 [Enterococcus faecium].	25.70	572	348	26	103	635	81	614	2e-09	71.6
tr:G1NSV2_MYOLU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.03	495	284	18	188	631	239	687	2e-09	71.6
tr:W5J7Z4_ANODA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.97	628	396	21	46	619	87	674	2e-09	71.6
rs:WP_001066135	DNA topoisomerase I [Helicobacter pylori].	23.75	522	333	17	103	583	73	570	2e-09	71.6
rs:WP_025407270	DNA topoisomerase I [Borrelia parkeri].	22.98	544	335	18	77	577	69	571	2e-09	71.6
rs:WP_027462956	DNA topoisomerase I [Deinococcus ficus].	22.22	612	313	24	3	530	5	537	2e-09	71.6
rs:WP_030149446	DNA topoisomerase I [Mycetocola saprophilus].	23.45	563	338	20	32	538	21	546	2e-09	71.6
rs:WP_044432270	DNA topoisomerase I [Acinetobacter pittii].	21.51	581	378	24	76	611	55	602	2e-09	71.6
rs:WP_040773167	DNA topoisomerase I [Nocardia pneumoniae].	23.06	607	324	23	2	530	17	558	2e-09	71.6
tr:Q5CBJ6_9THEM	RecName: Full=Reverse gyrase {ECO:0000256|HAMAP-Rule:MF_01125, ECO:0000256|RuleBase:RU004026};	23.63	474	273	16	81	533	644	1049	2e-09	71.6
rs:WP_000277571	DNA topoisomerase I [Helicobacter pylori].	23.08	468	308	12	99	537	77	521	2e-09	71.2
rs:WP_033622086	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	2e-09	71.6
rs:WP_002288411	MULTISPECIES: DNA topoisomerase I [Enterococcus].	25.70	572	348	26	103	635	81	614	2e-09	71.6
rs:WP_002339402	DNA topoisomerase 1 [Enterococcus faecium].	25.70	572	348	26	103	635	81	614	2e-09	71.6
rs:WP_041835763	DNA topoisomerase I [Acidothermus cellulolyticus].	21.92	584	359	21	3	538	1	535	2e-09	71.6
rs:WP_020026414	hypothetical protein [gamma proteobacterium SCGC AAA076-D13].	25.44	401	245	12	3	392	5	362	2e-09	71.6
rs:WP_038819903	DNA topoisomerase I [Pseudomonas aeruginosa].	21.66	517	288	18	74	537	59	511	2e-09	71.2
rs:WP_020023671	hypothetical protein [gamma proteobacterium SCGC AAA076-D02].	25.44	397	250	11	3	392	5	362	2e-09	71.6
rs:WP_045510901	hypothetical protein [bacterium UASB14].	21.80	656	409	26	3	614	5	600	2e-09	71.6
rs:WP_044726088	DNA topoisomerase I, partial [Escherichia coli].	26.91	353	216	16	73	400	74	409	2e-09	70.9
tr:J8Z6D6_ENTFC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.70	572	348	26	103	635	99	632	2e-09	71.6
rs:WP_034021225	DNA topoisomerase I [Pseudomonas aeruginosa].	21.48	512	295	17	74	537	59	511	2e-09	71.2
rs:WP_001066144	DNA topoisomerase I [Helicobacter pylori].	23.87	465	294	15	157	583	128	570	2e-09	71.2
tr:A0A086PLT6_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.44	611	389	23	3	564	6	574	2e-09	71.6
tr:K1WYH2_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	24.06	424	258	15	257	660	22	401	2e-09	70.9
tr:A0A0E0JZS4_ORYPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OPUNC02G14710.4};	22.09	602	366	25	64	610	415	968	2e-09	71.6
rs:WP_019260527	DNA topoisomerase I [Gardnerella vaginalis].	22.82	631	376	21	2	571	6	586	2e-09	71.6
rs:WP_017727298	hypothetical protein, partial [Bacillus sp. L1(2012)].	27.13	247	168	7	103	343	80	320	2e-09	70.1
rs:WP_004952687	DNA topoisomerase I [Streptomyces mobaraensis].	22.50	591	342	22	2	530	13	549	2e-09	71.6
rs:WP_000681521	DNA topoisomerase I [Helicobacter pylori].	22.81	640	402	24	3	614	4	579	2e-09	71.6
rs:WP_008777893	MULTISPECIES: DNA topoisomerase I [Parabacteroides].	22.66	534	338	16	3	520	5	479	2e-09	71.6
rs:WP_040703664	DNA topoisomerase I [Nocardia takedensis].	22.39	603	333	21	2	530	17	558	2e-09	71.6
tr:A0A0C2THH2_AMAMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.99	624	402	20	3	577	4	585	2e-09	71.6
rs:WP_000681409	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	2e-09	71.6
rs:WP_033694421	DNA topoisomerase, partial [Bacillus thuringiensis].	30.66	137	90	1	189	320	34	170	2e-09	68.6
rs:XP_012649667	uncharacterized protein [Babesia microti strain RI].	22.57	638	399	28	3	597	7	592	2e-09	71.2
rs:XP_007595647	DNA topoisomerase [Colletotrichum fioriniae PJ7].	21.87	567	348	20	3	521	4	523	2e-09	71.2
rs:WP_021770527	DNA topoisomerase I [Mitsuokella sp. oral taxon 131].	22.16	573	374	17	83	616	96	635	2e-09	71.6
rs:WP_033973543	DNA topoisomerase I [Pseudomonas aeruginosa].	21.37	613	370	21	74	641	59	604	2e-09	71.2
tr:G4URA7_NEUT9	SubName: Full=Prokaryotic type I DNA topoisomerase {ECO:0000313|EMBL:EGZ71954.1};	24.50	347	219	12	188	521	200	516	2e-09	71.2
tr:K6AC25_9PORP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.18	532	343	14	3	520	29	503	2e-09	71.6
rs:WP_008867038	DNA topoisomerase I [Flavobacteria bacterium MS024-3C].	24.51	563	348	21	3	550	5	505	2e-09	71.6
tr:K1UJ58_9ZZZZ	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EKC80054.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EKC80054.1}; Flags: Fragment;	30.77	130	81	1	238	358	41	170	2e-09	67.8
rs:XP_002368584	DNA topoisomerase III beta-1, putative [Toxoplasma gondii ME49].	21.12	606	380	22	3	564	6	557	2e-09	71.6
rs:WP_017575781	DNA topoisomerase I [Nocardiopsis kunsanensis].	21.75	593	342	22	3	530	25	560	2e-09	71.6
rs:WP_023647218	DNA topoisomerase I [actinobacterium LLX17].	23.60	589	328	24	3	528	4	533	2e-09	71.6
rs:WP_000655372	DNA topoisomerase I [Helicobacter pylori].	23.90	523	359	18	80	575	52	562	2e-09	71.2
rs:WP_033770366	DNA topoisomerase I, partial [Helicobacter pylori].	23.83	470	302	14	99	537	77	521	2e-09	71.2
tr:V4YZV7_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.44	611	389	23	3	564	6	574	2e-09	71.6
rs:WP_003640563	DNA topoisomerase I [Lactobacillus plantarum].	22.47	583	375	23	90	635	95	637	2e-09	71.2
rs:WP_033746263	DNA topoisomerase I [Helicobacter pylori].	23.29	468	307	12	99	537	77	521	2e-09	71.2
tr:N4VN06_COLOR	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ENH85237.1};	21.83	568	360	18	3	521	4	536	2e-09	71.2
rs:WP_016629581	hypothetical protein, partial [Enterococcus faecium].	41.12	107	59	1	103	205	3	109	2e-09	67.0
rs:WP_033744624	DNA topoisomerase I [Helicobacter pylori].	23.83	470	302	14	99	537	77	521	2e-09	71.2
tr:Q9R6Q0_MYCGL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.52	564	345	21	103	614	104	627	2e-09	71.2
rs:WP_012056085	DNA topoisomerase I [Parabacteroides distasonis].	22.18	532	343	14	3	520	5	479	2e-09	71.2
rs:XP_011638711	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha [Pogonomyrmex barbatus].	23.59	390	247	14	188	560	258	613	2e-09	71.6
rs:WP_038134722	DNA topoisomerase I [Thiomicrospira sp. Milos-T1].	23.76	463	298	14	76	520	52	477	2e-09	71.6
rs:XP_006103914	PREDICTED: DNA topoisomerase 3-alpha [Myotis lucifugus].	23.01	491	289	17	188	631	239	687	2e-09	71.6
rs:XP_008301573	PREDICTED: DNA topoisomerase 3-alpha [Stegastes partitus].	22.20	491	301	18	188	634	253	706	2e-09	71.6
rs:WP_027764162	DNA topoisomerase I [Streptomyces sp. CNS606].	23.83	600	328	25	2	530	13	554	2e-09	71.6
rs:WP_002320952	DNA topoisomerase I [Enterococcus faecium].	25.70	572	348	26	103	635	99	632	2e-09	71.2
rs:XP_004832692	DNA topoisomerase III, putative [Babesia equi].	24.39	611	363	28	5	563	7	570	2e-09	71.2
rs:WP_033774513	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	2e-09	71.2
rs:WP_014738751	DNA topoisomerase I [Modestobacter marinus].	22.59	664	348	31	3	574	29	618	2e-09	71.6
rs:WP_035374814	DNA topoisomerase I, partial [Acetobacter persici].	22.14	637	405	24	55	630	28	634	2e-09	71.6
rs:WP_004789614	DNA topoisomerase I [Borrelia afzelii].	23.28	653	386	25	2	599	5	597	2e-09	71.6
rs:WP_009433810	DNA topoisomerase I [Porphyromonas sp. oral taxon 279].	23.77	530	345	19	1	521	1	480	2e-09	71.2
rs:WP_014661753	DNA topoisomerase I [Helicobacter cetorum].	29.41	255	159	9	80	317	52	302	2e-09	71.2
rs:WP_000655367	DNA topoisomerase I [Helicobacter pylori].	29.63	270	167	10	80	330	52	317	2e-09	71.2
rs:WP_039088321	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	2e-09	71.2
rs:WP_035815296	DNA topoisomerase I, partial [Jiangella gansuensis].	22.17	663	391	28	2	591	13	623	2e-09	71.6
rs:WP_036589012	DNA topoisomerase III, partial [Paenibacillus sophorae].	33.06	121	76	2	495	615	21	136	2e-09	67.8
rs:WP_014486428	DNA topoisomerase I [Borrelia afzelii].	23.28	653	386	25	2	599	5	597	2e-09	71.2
rs:XP_012768565	DNA topoisomerase family protein, putative [Babesia bigemina].	22.98	644	409	27	1	599	1	602	2e-09	71.2
tr:G4TIC8_PIRID	SubName: Full=Related to DNA topoisomerase III alpha {ECO:0000313|EMBL:CCA71076.1};	22.50	600	365	24	36	585	15	564	2e-09	71.2
rs:WP_022668783	DNA topoisomerase I [Desulfospira joergensenii].	22.40	567	373	19	82	614	59	592	2e-09	71.2
rs:WP_000681416	DNA topoisomerase I [Helicobacter pylori].	22.54	639	405	21	3	614	4	579	2e-09	71.2
rs:WP_011601256	DNA topoisomerase I [Borrelia afzelii].	23.28	653	386	25	2	599	5	597	2e-09	71.2
rs:WP_005225215	MULTISPECIES: topoisomerase [Enterococcus].	41.12	107	59	1	103	205	3	109	2e-09	67.0
tr:O53042_HELPX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.74	642	400	23	3	614	4	579	2e-09	71.2
rs:XP_009798205	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Nicotiana sylvestris].	23.39	436	281	15	3	396	16	440	2e-09	70.9
rs:WP_015415282	DNA topoisomerase 1 [Desulfovibrio piezophilus].	21.81	596	384	19	76	631	53	606	2e-09	71.2
rs:WP_045275221	DNA topoisomerase I [Microbacterium ketosireducens].	22.91	515	305	18	77	538	67	542	2e-09	71.2
rs:WP_012473240	DNA topoisomerase I [Candidatus Amoebophilus asiaticus].	28.04	321	214	9	77	392	54	362	2e-09	71.2
rs:XP_007617066	PREDICTED: DNA topoisomerase 3-alpha isoform X4 [Cricetulus griseus].	21.40	486	309	17	188	634	162	613	2e-09	71.2
tr:A0A066W1D5_9BASI	SubName: Full=Prokaryotic type I DNA topoisomerase {ECO:0000313|EMBL:KDN47556.1};	22.40	643	391	24	3	577	4	606	2e-09	71.6
rs:WP_002206977	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	2e-09	71.2
rs:WP_033764451	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	2e-09	71.2
rs:WP_031249972	DNA topoisomerase I [Helicobacter pylori].	22.88	472	304	13	99	537	77	521	2e-09	71.2
tr:M3TUR3_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.55	558	326	22	32	530	14	535	2e-09	71.6
rs:WP_038332922	DNA topoisomerase I [Empedobacter falsenii].	28.35	321	213	6	77	392	54	362	2e-09	71.2
tr:W1YBX4_9ZZZZ	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ETJ39205.1}; Flags: Fragment;	32.52	123	79	3	245	363	10	132	2e-09	67.0
rs:WP_004137143	DNA topoisomerase I [Gardnerella vaginalis].	22.66	631	377	21	2	571	6	586	2e-09	71.2
rs:WP_014178442	DNA topoisomerase I [Streptomyces bingchenggensis].	22.48	596	334	21	2	530	13	547	2e-09	71.2
rs:XP_009363705	PREDICTED: uncharacterized protein LOC103953658 [Pyrus x bretschneideri].	25.17	298	189	8	64	333	407	698	2e-09	71.2
tr:S4EF11_ENTFC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.70	572	348	26	103	635	99	632	2e-09	71.2
rs:WP_000681430	DNA topoisomerase I [Helicobacter pylori].	23.12	640	400	25	3	614	4	579	2e-09	71.2
rs:XP_012226746	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Linepithema humile].	21.20	467	298	17	188	619	207	638	2e-09	71.6
tr:G5JLM4_9STAP	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.81	208	135	5	103	303	50	253	2e-09	68.6
rs:XP_005870224	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Myotis brandtii].	23.01	491	289	17	188	631	239	687	2e-09	71.2
tr:C2HAA3_ENTFC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.70	572	348	26	103	635	99	632	2e-09	71.2
rs:WP_046844366	DNA topoisomerase I ['Deinococcus soli' Cha et al. 2014].	23.21	586	339	22	3	530	9	541	2e-09	71.2
rs:XP_010635741	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Fukomys damarensis].	22.58	465	294	15	188	619	239	670	2e-09	71.2
rs:WP_001960813	DNA topoisomerase [Helicobacter pylori].	23.87	465	294	15	157	583	128	570	2e-09	71.2
rs:WP_017538191	MULTISPECIES: DNA topoisomerase I [Nocardiopsis].	22.87	586	345	22	2	530	24	559	2e-09	71.2
rs:XP_011878275	PREDICTED: DNA topoisomerase 3 isoform X2 [Vollenhovia emeryi].	21.59	616	404	24	46	619	101	679	2e-09	71.6
rs:WP_042636706	DNA topoisomerase I [Helicobacter pylori].	23.05	642	398	24	3	614	4	579	2e-09	71.2
rs:WP_000681475	DNA topoisomerase I [Helicobacter pylori].	22.86	643	398	25	3	614	4	579	2e-09	71.2
rs:WP_006704667	topoisomerase I [Candidatus Regiella insecticola].	22.40	491	291	17	187	633	199	643	2e-09	71.2
rs:XP_012226745	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Linepithema humile].	21.20	467	298	17	188	619	256	687	2e-09	71.6
tr:Q6AGT6_LEIXX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.71	590	341	22	2	530	39	574	2e-09	71.2
rs:WP_000681412	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	2e-09	71.2
rs:WP_027463868	hypothetical protein [Deinococcus ficus].	24.78	577	333	23	1	533	1	520	2e-09	71.2
rs:WP_019281567	hypothetical protein [Vibrio anguillarum].	35.14	111	62	5	2	108	3	107	2e-09	67.0
rs:WP_000681447	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	2e-09	71.2
rs:XP_005870225	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Myotis brandtii].	23.01	491	289	17	188	631	239	687	2e-09	71.2
rs:WP_000655370	DNA topoisomerase I [Helicobacter pylori].	30.20	255	157	8	80	317	52	302	2e-09	71.2
rs:XP_005870226	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Myotis brandtii].	23.03	495	284	18	188	631	188	636	2e-09	71.2
rs:WP_020540892	DNA topoisomerase I [Nonomuraea coxensis].	22.25	683	363	27	2	591	12	619	2e-09	71.2
rs:WP_032139562	DNA topoisomerase I [Rickettsia tamurae].	21.95	697	406	28	1	629	1	627	2e-09	71.2
rs:XP_008820178	PREDICTED: DNA topoisomerase 3-alpha [Nannospalax galili].	21.11	488	308	16	188	634	239	690	2e-09	71.2
rs:WP_044052320	DNA topoisomerase I [Borrelia afzelii].	23.28	653	386	25	2	599	5	597	2e-09	71.2
tr:A0A060CZA5_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	23.08	468	308	12	99	537	80	524	2e-09	70.9
rs:WP_044562983	DNA topoisomerase I [Azospirillum sp. B4].	21.56	640	403	21	55	629	30	635	2e-09	71.2
rs:WP_029588602	DNA topoisomerase I [Campylobacter jejuni].	22.39	652	398	23	3	618	5	584	2e-09	71.2
rs:WP_033595303	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	2e-09	71.2
rs:WP_031773420	DNA topoisomerase I [Pseudomonas aeruginosa].	22.44	517	284	19	74	537	59	511	2e-09	70.9
rs:WP_021755795	DNA topoisomerase I [Leifsonia xyli].	22.88	590	340	22	2	530	6	541	2e-09	71.2
rs:WP_001973100	DNA topoisomerase [Helicobacter pylori].	23.87	465	294	15	157	583	128	570	2e-09	70.9
rs:WP_003009917	DNA topoisomerase I [Leptospira weilii].	23.94	589	365	21	79	630	56	598	2e-09	70.9
tr:A0A094RFZ6_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KGA03558.1};	23.34	587	340	23	1	530	3	536	2e-09	71.2
rs:WP_004478055	DNA topoisomerase I [Leptospira santarosai].	23.94	589	374	21	76	629	52	601	2e-09	70.9
rs:WP_028787284	DNA topoisomerase I [Terrimonas ferruginea].	22.28	597	379	21	3	580	5	535	2e-09	71.2
tr:Q3TBE3_MOUSE	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	20.75	482	317	13	188	634	214	665	2e-09	71.2
rs:WP_017980954	reverse gyrase [Methanocaldococcus villosus].	24.24	524	307	21	82	581	651	1108	2e-09	71.2
rs:WP_001066147	DNA topoisomerase I [Helicobacter pylori].	23.87	465	294	15	157	583	128	570	2e-09	70.9
rs:WP_018386178	DNA topoisomerase I [Streptomyces vitaminophilus].	23.18	591	338	23	2	530	13	549	2e-09	71.2
rs:WP_033743595	DNA topoisomerase I [Helicobacter pylori].	22.81	640	402	24	3	614	4	579	2e-09	71.2
rs:XP_011878274	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Vollenhovia emeryi].	21.59	616	404	24	46	619	101	679	2e-09	71.2
tr:M3R6A4_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	23.83	470	302	15	99	537	77	521	2e-09	70.9
rs:WP_033763286	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	2e-09	71.2
rs:XP_007574411	PREDICTED: DNA topoisomerase 3-alpha [Poecilia formosa].	22.65	468	291	16	188	619	254	686	2e-09	71.2
rs:WP_023102685	DNA topoisomerase I [Pseudomonas aeruginosa].	22.24	517	285	18	74	537	59	511	2e-09	70.9
rs:WP_043553201	DNA topoisomerase I, partial [Acetobacter malorum].	22.45	637	403	24	55	630	28	634	2e-09	71.2
tr:A0A024SJE7_HYPJE	SubName: Full=Prokaryotic type I DNA topoisomerase {ECO:0000313|EMBL:ETS05640.1};	22.30	556	354	22	3	520	4	519	2e-09	70.9
rs:WP_032825418	topoisomerase I, partial [Oenococcus oeni].	29.51	122	84	1	432	551	15	136	2e-09	67.0
rs:WP_038418238	DNA topoisomerase I [Helicobacter pylori].	24.10	498	313	17	80	538	52	523	2e-09	70.9
rs:WP_029018600	DNA topoisomerase I [actinobacterium SCGC AAA028-I14].	23.59	585	339	24	1	530	9	540	2e-09	71.2
rs:WP_001957767	DNA topoisomerase I [Helicobacter pylori].	22.81	640	402	24	3	614	4	579	2e-09	70.9
rs:WP_008772731	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	22.18	532	343	14	3	520	5	479	2e-09	71.2
rs:WP_046926801	DNA topoisomerase I [Streptomyces lydicus].	22.69	595	335	22	2	530	14	549	2e-09	71.2
rs:WP_038293838	DNA topoisomerase I, partial [alpha proteobacterium SCGC AB-629-F11].	23.22	646	393	27	74	658	51	654	2e-09	71.2
rs:WP_015643453	topoisomerase I [Helicobacter pylori].	23.94	497	313	16	80	537	52	522	2e-09	70.9
rs:XP_005887347	PREDICTED: DNA topoisomerase 3-alpha [Bos mutus].	22.67	494	292	18	188	634	239	689	2e-09	71.2
rs:WP_046992000	DNA topoisomerase I [Arcobacter butzleri].	23.80	563	343	22	3	533	4	512	3e-09	70.9
rs:WP_000681473	DNA topoisomerase I [Helicobacter pylori].	22.54	639	405	21	3	614	4	579	3e-09	70.9
rs:WP_000681401	DNA topoisomerase I [Helicobacter pylori].	23.05	642	398	24	3	614	4	579	3e-09	70.9
rs:WP_008545028	DNA topoisomerase I [Candidatus Pelagibacter sp. HTCC7211].	21.88	576	344	20	1	534	1	512	3e-09	71.2
rs:WP_036617743	DNA topoisomerase I [Parabacteroides distasonis].	22.18	532	343	14	3	520	5	479	3e-09	70.9
rs:WP_023660707	DNA topoisomerase I [Pseudomonas taiwanensis].	23.83	470	307	13	84	533	69	507	3e-09	70.9
sp:RGYR_ARCFU	RecName: Full=Reverse gyrase {ECO:0000255|HAMAP-Rule:MF_01125}; Includes: RecName: Full=Helicase {ECO:0000255|HAMAP-Rule:MF_01125}; EC=3.6.4.12 {ECO:0000255|HAMAP-Rule:MF_01125}; Includes: RecName: Full=Topoisomerase {ECO:0000255|HAMAP-Rule:MF_01125}; EC=5.99.1.3 {ECO:0000255|HAMAP-Rule:MF_01125};	22.29	525	292	23	81	574	607	1046	3e-09	71.2
rs:WP_001942503	DNA topoisomerase [Helicobacter pylori].	23.87	465	294	15	157	583	128	570	3e-09	70.9
rs:WP_009643082	DNA topoisomerase, partial [Mogibacterium sp. CM50].	32.14	168	110	2	420	587	14	177	3e-09	67.4
rs:WP_030782197	DNA topoisomerase I [Streptomyces sp. NRRL S-920].	22.24	589	343	20	2	530	13	546	3e-09	71.2
rs:WP_021678244	hypothetical protein, partial [Porphyromonas gingivalis].	31.47	143	89	5	544	684	16	151	3e-09	67.4
rs:WP_031811093	DNA topoisomerase III, partial [Staphylococcus aureus].	37.30	126	62	6	3	117	4	123	3e-09	66.6
rs:WP_033748728	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	3e-09	70.9
rs:WP_012538567	DNA topoisomerase I [Borrelia duttonii].	24.91	582	338	25	77	604	69	605	3e-09	70.9
rs:WP_025408392	DNA topoisomerase I [Borrelia coriaceae].	23.58	547	328	20	77	577	69	571	3e-09	70.9
rs:WP_004008771	DNA topoisomerase I [Mobiluncus curtisii].	21.83	655	363	22	2	571	7	597	3e-09	71.2
rs:WP_011360529	DNA topoisomerase I [Synechococcus sp. CC9902].	22.13	628	373	25	3	572	5	574	3e-09	71.2
rs:WP_025952447	DNA topoisomerase I, partial [Prochlorococcus sp. scB243_495P20].	24.19	430	251	14	188	572	175	574	3e-09	70.9
rs:WP_042857410	DNA topoisomerase III, partial [Staphylococcus aureus].	37.72	114	68	2	73	183	6	119	3e-09	66.6
rs:WP_000681492	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	23	3	614	4	579	3e-09	70.9
tr:A0A075WJY4_ARCFL	RecName: Full=Reverse gyrase {ECO:0000256|HAMAP-Rule:MF_01125, ECO:0000256|RuleBase:RU004026};	22.29	525	292	23	81	574	607	1046	3e-09	71.2
rs:XP_010484154	PREDICTED: DNA topoisomerase 3-alpha-like [Camelina sativa].	21.45	634	405	25	3	585	12	603	3e-09	71.2
rs:WP_029478369	DNA topoisomerase I [Deinococcus frigens].	22.43	584	346	20	3	530	5	537	3e-09	71.2
rs:XP_002837817	hypothetical protein [Tuber melanosporum Mel28].	22.18	559	336	19	76	587	91	597	3e-09	70.9
rs:WP_001914871	DNA topoisomerase I [Helicobacter pylori].	23.08	468	308	11	99	537	77	521	3e-09	70.9
rs:WP_044709690	DNA topoisomerase I, partial [Escherichia coli].	29.49	234	133	9	187	401	76	296	3e-09	68.9
rs:WP_028321406	DNA topoisomerase I [Desulfatiglans anilini].	22.83	635	408	23	83	673	60	656	3e-09	70.9
rs:WP_021309996	DNA topoisomerase I [Helicobacter pylori].	24.10	498	313	17	80	538	52	523	3e-09	70.9
rs:WP_036897368	DNA topoisomerase I [Prochlorococcus marinus].	24.78	335	202	10	258	572	270	574	3e-09	70.9
rs:WP_001937571	DNA topoisomerase [Helicobacter pylori].	24.07	457	287	15	157	575	128	562	3e-09	70.9
rs:WP_044544802	DNA topoisomerase I, partial [Parabacteroides distasonis].	22.66	534	338	16	3	520	5	479	3e-09	70.9
tr:K8CQN7_CROSK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.98	367	222	13	291	633	1	334	3e-09	70.5
rs:WP_034522148	DNA topoisomerase I [Bifidobacterium sp. MSTE12].	22.46	650	367	23	2	571	6	598	3e-09	71.2
rs:WP_011255493	DNA topoisomerase I [Ehrlichia ruminantium].	23.27	692	402	29	1	629	1	626	3e-09	70.9
rs:WP_031755155	DNA topoisomerase I [Pseudomonas aeruginosa].	22.27	512	291	18	74	537	59	511	3e-09	70.9
rs:WP_023098077	DNA topoisomerase I [Pseudomonas aeruginosa].	22.22	513	290	17	74	537	59	511	3e-09	70.9
rs:WP_027383415	DNA topoisomerase I [Chryseobacterium caeni].	23.66	558	341	19	3	538	5	499	3e-09	70.9
rs:WP_042427852	DNA topoisomerase I [Streptacidiphilus anmyonensis].	23.17	600	336	25	2	530	13	558	3e-09	70.9
rs:WP_043483740	DNA topoisomerase I [Arthrobacter sp. SPG23].	21.56	589	363	20	2	538	10	551	3e-09	70.9
tr:K1SMJ4_9ZZZZ	SubName: Full=Topoisomerase IA {ECO:0000313|EMBL:EKC48536.1}; Flags: Fragment;	31.86	113	61	4	2	107	3	106	3e-09	66.2
rs:YP_007354228	DNA topoisomerase 1 [Acanthamoeba polyphaga moumouvirus].	24.11	535	305	23	38	521	23	507	3e-09	70.9
rs:WP_044115431	DNA topoisomerase I [Porphyromonas sp. KLE 1280].	23.77	530	345	19	1	521	1	480	3e-09	70.9
tr:H1DB08_9FUSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.79	323	171	12	264	561	33	321	3e-09	70.5
rs:WP_026846612	DNA topoisomerase I [Geodermatophilaceae bacterium URHA0031].	22.74	664	347	30	3	574	29	618	3e-09	70.9
rs:WP_004804473	hypothetical protein, partial [Eggerthia catenaformis].	31.76	170	108	4	420	587	42	205	3e-09	67.8
tr:A0A087Y9R3_POEFO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.65	468	291	16	188	619	214	646	3e-09	70.9
tr:A0A0D0G883_LACBR	SubName: Full=Lactobacillus brevis strain TMW 1.313 Scaffold_1_TMW1313, whole genome shotgun sequence {ECO:0000313|EMBL:KIO95764.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIO95764.1};	21.25	513	321	18	157	629	17	486	3e-09	70.5
rs:WP_028123880	DNA topoisomerase I [Entomoplasma melaleucae].	23.82	617	363	25	61	625	48	609	3e-09	70.5
tr:T5DB11_HELPX	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EQL69640.1};	23.44	465	296	14	157	583	1	443	3e-09	70.5
tr:H2EFW7_9VIRU	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:AEX63019.1};	24.11	535	305	23	38	521	23	507	3e-09	70.9
rs:WP_000681507	DNA topoisomerase I [Helicobacter pylori].	22.81	640	402	24	3	614	4	579	3e-09	70.9
rs:WP_000681432	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	3e-09	70.9
rs:WP_000681522	DNA topoisomerase I [Helicobacter pylori].	23.21	642	397	24	3	614	4	579	3e-09	70.9
rs:WP_000681436	DNA topoisomerase I [Helicobacter pylori].	22.38	639	406	22	3	614	4	579	3e-09	70.9
rs:WP_033596589	DNA topoisomerase I [Helicobacter pylori].	22.97	640	401	24	3	614	4	579	3e-09	70.9
rs:WP_040155991	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	3e-09	70.9
rs:WP_043667574	DNA topoisomerase I [Streptomyces xylophagus].	22.91	598	329	21	2	530	13	547	3e-09	70.9
rs:WP_000054712	DNA topoisomerase I [Leptospira interrogans].	23.70	675	386	25	3	630	4	596	3e-09	70.5
tr:Q3TPE4_MOUSE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.54	482	318	13	188	634	239	690	3e-09	70.9
rs:WP_024521591	DNA topoisomerase I [Lactobacillus plantarum].	22.16	582	378	22	90	635	95	637	3e-09	70.9
tr:A0A024GYV1_9MICC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.32	587	358	22	2	538	10	548	3e-09	70.9
rs:WP_001918317	DNA topoisomerase [Helicobacter pylori].	23.56	522	334	17	103	583	73	570	3e-09	70.9
rs:WP_011531122	DNA topoisomerase I [Deinococcus geothermalis].	23.43	589	334	22	3	530	5	537	3e-09	70.9
rs:WP_011155021	DNA topoisomerase I [Ehrlichia ruminantium].	23.27	692	402	29	1	629	1	626	3e-09	70.9
rs:WP_014887830	topoisomerase I [secondary endosymbiont of Ctenarytaina eucalypti].	22.13	601	381	17	74	633	77	631	3e-09	70.9
rs:WP_004490023	DNA topoisomerase I [Leptospira santarosai].	23.74	657	408	25	3	630	4	596	3e-09	70.5
tr:A0A0A1PJ72_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.82	427	246	20	1	392	3	389	3e-09	70.9
rs:XP_009436168	PREDICTED: DNA topoisomerase 3-beta-1 isoform X6 [Pan troglodytes].	22.50	360	229	11	238	585	116	437	3e-09	70.9
rs:WP_033622936	DNA topoisomerase I [Helicobacter pylori].	23.83	470	302	13	99	537	77	521	3e-09	70.5
rs:WP_000277575	DNA topoisomerase I [Helicobacter pylori].	22.65	468	310	12	99	537	77	521	3e-09	70.5
rs:WP_033993318	DNA topoisomerase I [Pseudomonas aeruginosa].	22.63	517	283	19	74	537	59	511	3e-09	70.5
rs:WP_014155474	MULTISPECIES: DNA topoisomerase I [Streptomyces].	22.03	590	346	21	2	530	11	547	3e-09	70.9
rs:WP_033592450	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	3e-09	70.9
tr:K1U6P0_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EKC67121.1}; Flags: Fragment;	26.83	328	194	11	3	319	5	297	3e-09	68.9
rs:WP_030122938	DNA topoisomerase I [[Kitasatospora] papulosa].	22.03	590	346	21	2	530	11	547	3e-09	70.9
rs:WP_013414752	DNA topoisomerase I [Rhodococcus equi].	22.80	592	338	21	2	530	17	552	3e-09	70.9
rs:WP_041767061	DNA topoisomerase I [Leifsonia xyli].	22.71	590	341	22	2	530	6	541	3e-09	70.9
rs:WP_041784010	hypothetical protein [Streptococcus anginosus].	28.77	146	90	3	187	318	32	177	3e-09	67.4
rs:WP_014683881	DNA topoisomerase I [Deinococcus gobiensis].	22.79	588	344	22	3	530	5	542	3e-09	70.9
rs:WP_000655377	DNA topoisomerase I [Helicobacter pylori].	29.80	255	158	8	80	317	52	302	3e-09	70.5
rs:WP_014661005	DNA topoisomerase I [Helicobacter cetorum].	23.21	530	354	15	82	578	54	563	3e-09	70.5
rs:XP_008154451	PREDICTED: DNA topoisomerase 3-alpha [Eptesicus fuscus].	22.83	495	291	18	188	634	239	690	3e-09	70.9
rs:WP_000047315	DNA topoisomerase III [Bacillus cereus].	36.11	108	57	5	3	105	5	105	3e-09	66.2
rs:WP_024133601	hypothetical protein [Salmonella enterica].	23.46	358	227	12	295	633	1	330	3e-09	70.5
rs:WP_005515801	DNA topoisomerase I [Rhodococcus equi].	22.80	592	338	21	2	530	17	552	3e-09	70.9
rs:WP_003837688	DNA topoisomerase I [Bifidobacterium dentium].	22.46	650	367	23	2	571	6	598	3e-09	70.9
rs:WP_040179383	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	3e-09	70.5
rs:XP_009026009	hypothetical protein HELRODRAFT_114559 [Helobdella robusta].	23.26	619	381	25	46	619	59	628	3e-09	70.9
rs:WP_033123370	DNA topoisomerase I [Helicobacter pylori].	23.17	643	396	26	3	614	4	579	3e-09	70.5
tr:A0A069CW26_9LACT	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:GAK31592.1};	32.88	146	84	5	1	137	2	142	3e-09	67.4
rs:XP_010366068	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Rhinopithecus roxellana].	21.49	484	311	14	188	634	239	690	3e-09	70.9
rs:WP_044779754	DNA topoisomerase I [Campylobacter jejuni].	22.39	652	398	23	3	618	5	584	3e-09	70.5
rs:WP_037360135	DNA topoisomerase I [Schleiferia thermophila].	25.80	376	237	13	157	520	132	477	3e-09	70.5
rs:WP_041271527	DNA topoisomerase I, partial [Desulfovibrio aespoeensis].	23.86	570	350	24	103	631	80	606	3e-09	70.9
rs:WP_011693180	DNA topoisomerase I [Arthrobacter sp. FB24].	21.56	589	363	20	2	538	10	551	3e-09	70.9
rs:WP_034555286	DNA topoisomerase I, partial [Helicobacter apodemus].	24.72	453	276	15	157	579	40	457	3e-09	70.5
rs:WP_017850207	DNA topoisomerase I [Leptospira interrogans].	23.74	674	387	25	3	630	4	596	3e-09	70.5
rs:WP_000047322	DNA topoisomerase III [Bacillus thuringiensis].	36.11	108	57	5	3	105	5	105	3e-09	66.2
rs:WP_001940876	DNA topoisomerase I [Helicobacter pylori].	23.05	642	398	24	3	614	4	579	3e-09	70.5
rs:WP_000681499	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	3e-09	70.5
rs:WP_000681438	DNA topoisomerase I [Helicobacter pylori].	23.02	643	397	25	3	614	4	579	3e-09	70.5
rs:XP_007703913	hypothetical protein COCSADRAFT_163916 [Bipolaris sorokiniana ND90Pr].	21.91	566	359	23	3	525	5	530	3e-09	70.5
rs:WP_043961495	DNA topoisomerase I [Micromonospora carbonacea].	22.29	637	373	25	2	571	9	590	3e-09	70.9
rs:WP_015122729	DNA topoisomerase I [Rivularia sp. PCC 7116].	22.10	629	354	20	3	560	4	567	3e-09	70.9
rs:WP_008336353	DNA topoisomerase I [Sulfurimonas gotlandica].	22.53	577	326	21	1	533	1	500	3e-09	70.5
tr:A0A073I4G1_9PORP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.18	532	343	14	3	520	42	516	3e-09	70.5
rs:WP_023104979	DNA topoisomerase I [Pseudomonas aeruginosa].	21.86	517	287	18	74	537	59	511	3e-09	70.5
rs:WP_001066138	DNA topoisomerase I [Helicobacter pylori].	23.56	522	334	17	103	583	73	570	3e-09	70.5
rs:WP_031040478	MULTISPECIES: DNA topoisomerase I [Streptomyces].	23.50	566	320	21	32	530	28	547	3e-09	70.9
rs:WP_000681420	DNA topoisomerase I [Helicobacter pylori].	22.86	643	398	25	3	614	4	579	3e-09	70.5
tr:Q6WWY9_PSEAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.44	508	295	18	74	537	51	503	3e-09	70.5
rs:WP_002597113	hypothetical protein [Clostridium colicanis].	35.20	125	55	6	2	109	3	118	3e-09	66.2
tr:Z2D976_PSEAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.03	456	274	19	187	616	1	405	3e-09	69.7
rs:XP_003602653	DNA topoisomerase [Medicago truncatula].	23.74	438	275	17	3	396	9	431	3e-09	70.5
rs:WP_029330313	DNA topoisomerase I [Mycoplasma cloacale].	25.59	383	232	15	35	393	21	374	3e-09	70.5
rs:WP_001066148	DNA topoisomerase I [Helicobacter pylori].	23.87	465	294	15	157	583	128	570	3e-09	70.5
tr:A0A094FUR7_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY92408.1};	21.93	570	365	20	3	532	6	535	3e-09	70.9
rs:WP_000681413	DNA topoisomerase I [Helicobacter pylori].	22.54	639	405	21	3	614	4	579	4e-09	70.5
rs:WP_044794031	DNA topoisomerase I [Campylobacter jejuni].	22.39	652	398	23	3	618	5	584	4e-09	70.5
rs:WP_000277570	DNA topoisomerase I [Helicobacter pylori].	22.69	476	300	11	99	537	77	521	4e-09	70.5
rs:XP_002997323	DNA topoisomerase, putative [Phytophthora infestans T30-4].	25.06	443	275	21	1	398	1	431	4e-09	70.5
rs:WP_021173223	DNA topoisomerase I [Helicobacter pylori].	23.05	642	398	24	3	614	4	579	4e-09	70.5
rs:WP_042539705	DNA topoisomerase I [Microbacterium sp. MEJ108Y].	22.28	615	321	24	2	538	6	541	4e-09	70.9
tr:A0A087PLJ9_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.45	637	403	24	55	630	28	634	4e-09	70.5
rs:XP_009130424	PREDICTED: DNA topoisomerase 3-alpha [Brassica rapa].	21.34	642	397	24	3	585	12	604	4e-09	70.5
rs:WP_030015206	DNA topoisomerase I [Curtobacterium sp. S6].	22.52	555	342	21	32	530	28	550	4e-09	70.9
tr:A0A0B0HQ32_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.52	123	76	3	276	392	4	125	4e-09	67.0
rs:WP_047022332	DNA topoisomerase I [Arcobacter butzleri].	23.45	563	345	22	3	533	4	512	4e-09	70.5
rs:WP_000681509	DNA topoisomerase I [Helicobacter pylori].	22.81	640	402	24	3	614	4	579	4e-09	70.5
rs:WP_033765728	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	4e-09	70.5
gpu:LN828718_421	DNA topoisomerase 1 [endosymbiont DhMRE of Dentiscutata heterogama]	24.49	539	318	24	39	533	25	518	4e-09	70.1
tr:F6FHS3_MYCHI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00003390}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.83	591	385	16	83	630	66	622	4e-09	70.5
rs:WP_000277561	DNA topoisomerase I [Helicobacter pylori].	22.86	468	309	12	99	537	77	521	4e-09	70.5
rs:WP_020028714	hypothetical protein [gamma proteobacterium SCGC AAA076-F14].	25.44	401	245	12	3	392	5	362	4e-09	70.5
rs:WP_004590021	reverse gyrase, partial [Methanocaldococcus villosus].	24.24	524	307	21	82	581	562	1019	4e-09	70.9
rs:WP_029170723	DNA topoisomerase I, partial [Cloacimonetes bacterium SCGC AAA255-C20].	25.63	437	256	18	225	629	21	420	4e-09	70.1
rs:WP_033618827	DNA topoisomerase I [Helicobacter pylori].	23.83	470	302	13	99	537	77	521	4e-09	70.5
rs:XP_008060812	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Tarsius syrichta].	22.22	486	305	17	188	634	239	690	4e-09	70.5
rs:WP_008152743	hypothetical protein, partial [Parabacteroides johnsonii].	24.62	398	251	10	3	391	5	362	4e-09	69.3
rs:WP_030524188	DNA topoisomerase I [Nocardia rhamnosiphila].	22.09	602	334	22	2	530	17	556	4e-09	70.5
tr:S9R5V8_9RHOB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	24.09	328	204	8	1	312	1	299	4e-09	70.1
rs:WP_001950177	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	4e-09	70.5
rs:WP_000681410	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	4e-09	70.5
rs:WP_004129275	DNA topoisomerase I [Gardnerella vaginalis].	22.77	628	378	20	2	571	6	584	4e-09	70.5
rs:WP_023103773	DNA topoisomerase I [Pseudomonas aeruginosa].	21.66	517	288	18	74	537	59	511	4e-09	70.1
rs:WP_016916640	DNA topoisomerase I [Rickettsia honei].	21.89	699	404	27	1	629	1	627	4e-09	70.5
rs:WP_015181243	DNA topoisomerase I [Microcoleus sp. PCC 7113].	20.83	576	357	15	3	530	4	528	4e-09	70.5
tr:A0A0E0JZS6_ORYPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OPUNC02G14710.6};	25.00	384	242	15	64	413	415	786	4e-09	70.9
rs:WP_000681433	DNA topoisomerase I [Helicobacter pylori].	22.81	640	402	24	3	614	4	579	4e-09	70.5
rs:WP_033754690	DNA topoisomerase I [Helicobacter pylori].	23.40	470	304	14	99	537	9	453	4e-09	70.1
rs:WP_033609400	topoisomerase I, partial [Lactobacillus plantarum].	34.81	135	82	3	189	317	3	137	4e-09	67.0
rs:WP_032590264	DNA topoisomerase I [Campylobacter jejuni].	23.01	652	394	25	3	618	5	584	4e-09	70.5
tr:I1Q1J5_ORYGL	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	27.69	260	160	9	64	303	339	590	4e-09	70.5
rs:WP_046767175	DNA topoisomerase I, partial [Jiangella alkaliphila].	21.77	611	335	22	2	538	13	554	4e-09	70.5
rs:WP_001963288	DNA topoisomerase I [Helicobacter pylori].	22.81	640	402	24	3	614	4	579	4e-09	70.5
tr:A0A0E0E0K8_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OMERI06G12680.1};	24.93	373	243	12	71	413	46	411	4e-09	70.1
rs:WP_033644918	DNA topoisomerase, partial [Enterococcus faecium].	33.96	106	62	3	1	103	1	101	4e-09	65.5
tr:A0A0C7NE35_9SACH	SubName: Full=LALA0S12e02586g1_1 {ECO:0000313|EMBL:CEP64597.1};	23.23	452	276	17	3	401	5	438	4e-09	70.1
rs:WP_014215391	DNA topoisomerase I [Pediococcus claussenii].	23.30	558	361	19	103	629	83	604	4e-09	70.5
tr:G2HS89_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.10	522	321	22	44	533	3	486	4e-09	70.5
rs:WP_026882032	hypothetical protein [Clostridium akagii].	36.29	124	55	6	2	109	3	118	4e-09	66.2
rs:WP_000681506	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	4e-09	70.5
rs:WP_000681417	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	4e-09	70.5
rs:WP_014469493	DNA topoisomerase I [Arcobacter butzleri].	23.62	563	344	22	3	533	4	512	4e-09	70.5
tr:K2DHP7_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EKE05216.1}; Flags: Fragment;	31.14	167	103	5	163	320	17	180	4e-09	67.0
rs:WP_045174597	reverse gyrase [Caldicellulosiruptor sp. Wai35.B1].	23.09	485	268	18	81	536	662	1070	4e-09	70.5
rs:WP_000681494	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	4e-09	70.5
rs:XP_007688143	hypothetical protein COCMIDRAFT_95795 [Bipolaris oryzae ATCC 44560].	21.42	565	363	22	3	525	5	530	4e-09	70.1
rs:XP_008958125	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Pan paniscus].	22.51	342	222	10	256	585	165	475	4e-09	70.5
rs:WP_001946536	DNA topoisomerase I [Helicobacter pylori].	23.02	643	397	26	3	614	4	579	4e-09	70.5
rs:WP_002208130	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	4e-09	70.5
rs:WP_039085302	DNA topoisomerase I [Helicobacter pylori].	22.86	468	309	11	99	537	77	521	4e-09	70.1
tr:W7D2R6_9LIST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.00	250	157	8	103	343	80	320	4e-09	68.9
tr:T0RV12_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.21	616	381	25	3	574	57	624	4e-09	70.5
rs:WP_001970510	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	4e-09	70.5
rs:WP_000681435	DNA topoisomerase I [Helicobacter pylori].	22.81	640	402	24	3	614	4	579	4e-09	70.5
tr:K2F398_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.64	592	384	20	76	631	54	607	4e-09	70.1
rs:WP_009459295	MULTISPECIES: DNA topoisomerase I [Fischerella].	22.78	619	370	19	3	564	4	571	4e-09	70.5
rs:WP_045004125	DNA topoisomerase I [Helicobacter pylori].	23.33	643	395	26	3	614	4	579	4e-09	70.1
rs:WP_000681512	DNA topoisomerase I [Helicobacter pylori].	23.05	642	398	24	3	614	4	579	4e-09	70.1
rs:WP_039087789	DNA topoisomerase I [Helicobacter pylori].	23.56	522	334	17	103	583	73	570	4e-09	70.1
rs:XP_012256009	PREDICTED: DNA topoisomerase 3-alpha [Athalia rosae].	21.77	620	393	19	46	616	98	674	4e-09	70.5
rs:WP_000681515	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	4e-09	70.1
tr:J0DQX4_HELPX	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EJB88453.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EJB88453.1};	29.80	255	158	8	80	317	52	302	4e-09	69.7
rs:WP_002928190	DNA topoisomerase I [Campylobacter jejuni].	21.73	658	395	22	3	618	5	584	4e-09	70.1
tr:W5HTD1_WHEAT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.05	576	364	22	9	536	263	801	4e-09	70.5
tr:N6UAY1_DENPD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.12	480	276	18	188	619	206	640	4e-09	70.1
rs:WP_043594793	DNA topoisomerase I [Frigoribacterium sp. MEB024].	23.29	601	333	21	2	528	6	552	4e-09	70.5
rs:WP_044277903	hypothetical protein, partial [Campylobacter jejuni].	52.94	68	28	1	161	224	5	72	4e-09	65.1
rs:WP_023049409	hypothetical protein [Pseudomonas putida].	23.43	478	315	13	84	541	69	515	4e-09	70.1
rs:WP_002902895	DNA topoisomerase I [Campylobacter jejuni].	22.24	652	399	23	3	618	5	584	4e-09	70.1
rs:XP_002847827	DNA topoisomerase III [Arthroderma otae CBS 113480].	23.04	638	380	26	3	573	6	599	4e-09	70.1
rs:XP_009436164	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Pan troglodytes].	22.51	342	222	10	256	585	165	475	4e-09	70.1
rs:WP_020762913	DNA topoisomerase I [Leptospira kirschneri].	23.89	678	377	28	3	630	4	592	4e-09	70.1
rs:XP_006279975	hypothetical protein CARUB_v10025845mg [Capsella rubella].	21.29	634	406	25	3	585	12	603	4e-09	70.5
rs:WP_041645026	DNA topoisomerase I [Arcobacter butzleri].	23.62	563	344	22	3	533	4	512	4e-09	70.1
rs:WP_021172657	DNA topoisomerase I [Helicobacter pylori].	22.32	466	313	11	99	537	77	520	4e-09	70.1
rs:WP_005314340	DNA topoisomerase I [Streptomyces pristinaespiralis].	22.18	595	337	21	2	530	13	547	4e-09	70.5
rs:WP_026938559	DNA topoisomerase I [Helicobacter pylori].	23.05	642	398	24	3	614	4	579	4e-09	70.1
rs:WP_024800961	DNA topoisomerase I [Nocardia sp. BMG51109].	22.19	604	334	21	2	530	22	564	4e-09	70.5
rs:WP_029657415	DNA topoisomerase I, partial [Helicobacter pylori].	29.80	255	158	8	80	317	52	302	4e-09	69.7
rs:XP_009798204	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Nicotiana sylvestris].	23.39	436	281	15	3	396	16	440	4e-09	69.7
rs:WP_001903125	DNA topoisomerase I [Helicobacter pylori].	22.86	468	309	13	99	537	77	521	4e-09	70.1
rs:WP_034018030	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	27.95	229	140	9	1	217	1	216	4e-09	67.0
rs:WP_039821720	DNA topoisomerase I [Nocardia testacea].	22.26	602	333	22	2	530	17	556	4e-09	70.5
tr:J0K782_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	22.65	468	310	13	99	537	77	521	4e-09	69.7
rs:WP_034727506	hypothetical protein, partial [Bacteriovorax sp. BSW11_IV].	23.21	616	381	25	3	574	70	637	4e-09	70.1
rs:WP_000655253	DNA topoisomerase I [Helicobacter pylori].	23.87	465	294	15	157	583	128	570	4e-09	70.1
rs:WP_029454711	DNA topoisomerase I [Candidatus Pelagibacter ubique].	21.53	576	346	19	1	534	1	512	4e-09	70.5
rs:WP_040257479	DNA topoisomerase I [Rickettsia hoogstraalii].	22.09	697	405	28	1	629	1	627	5e-09	70.1
rs:WP_001954546	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	5e-09	70.1
tr:A0A0D8QLB4_RAOPL	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KJG31733.1};	38.10	84	46	4	31	110	10	91	5e-09	65.5
rs:WP_010423404	DNA topoisomerase I [Rickettsia helvetica].	22.69	683	418	28	1	629	1	627	5e-09	70.1
rs:WP_026529492	DNA topoisomerase I [Arthrobacter sanguinis].	21.65	582	355	20	2	530	12	545	5e-09	70.5
rs:XP_012294193	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Aotus nancymaae].	23.23	465	291	15	188	619	239	670	5e-09	70.5
tr:W6FUY3_NODSP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.31	427	273	11	187	574	144	546	5e-09	70.1
rs:WP_014535992	topoisomerase I [Helicobacter pylori].	22.48	467	311	12	99	537	77	520	5e-09	69.7
rs:WP_046993897	DNA topoisomerase I [Arcobacter butzleri].	23.62	563	344	22	3	533	4	512	5e-09	70.1
tr:M6ADH4_9LEPT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.98	659	404	26	3	630	5	597	5e-09	70.1
rs:WP_001961309	DNA topoisomerase I [Helicobacter pylori].	22.86	643	398	23	3	614	4	579	5e-09	70.1
rs:WP_018623230	DNA topoisomerase I [Spirosoma luteum].	26.44	329	217	9	74	392	51	364	5e-09	70.1
rs:WP_000681428	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	5e-09	70.1
rs:WP_036059798	DNA topoisomerase I [Leptospira sp. P2653].	23.98	659	404	26	3	630	4	596	5e-09	70.1
rs:WP_033600427	DNA topoisomerase I [Helicobacter pylori].	30.20	255	157	9	80	317	52	302	5e-09	70.1
tr:K2LIP9_HELPX	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EKE89860.1};	29.36	235	141	7	103	317	73	302	5e-09	68.6
rs:WP_020848635	DNA topoisomerase I [Arcobacter butzleri].	23.62	563	344	22	3	533	4	512	5e-09	70.1
rs:WP_046995026	DNA topoisomerase I [Arcobacter butzleri].	23.45	563	345	22	3	533	4	512	5e-09	70.1
rs:WP_019948085	hypothetical protein [Hymenobacter aerophilus].	22.81	491	291	13	74	526	51	491	5e-09	70.1
rs:WP_018135954	DNA topoisomerase I [Campylobacter curvus].	23.02	656	381	24	3	614	4	579	5e-09	70.1
rs:WP_007902332	DNA topoisomerase I [Prevotella stercorea].	25.00	408	241	13	3	392	5	365	5e-09	70.1
rs:WP_036324537	DNA topoisomerase I [Microbispora sp. ATCC PTA-5024].	22.66	684	359	30	2	591	12	619	5e-09	70.1
tr:M2X4Y3_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.59	585	338	21	4	530	1	534	5e-09	70.1
rs:WP_026940978	DNA topoisomerase I [Hellea balneolensis].	23.68	570	353	22	1	537	1	521	5e-09	70.1
rs:XP_008120113	PREDICTED: DNA topoisomerase 3-alpha isoform X4 [Anolis carolinensis].	23.39	419	254	16	251	634	251	637	5e-09	70.1
rs:WP_035727327	DNA topoisomerase I [Flexibacter elegans].	23.78	471	304	12	74	520	51	490	5e-09	70.1
rs:WP_025375806	DNA topoisomerase I [Borrelia parkeri].	22.79	544	336	18	77	577	69	571	5e-09	70.1
rs:WP_024368809	DNA topoisomerase I [Helicobacter pylori].	23.05	642	398	24	3	614	4	579	5e-09	70.1
rs:WP_032592152	DNA topoisomerase I [Campylobacter jejuni].	22.24	652	399	23	3	618	5	584	5e-09	70.1
rs:WP_014127851	topoisomerase [Thermoproteus tenax].	20.40	603	367	20	10	583	704	1222	5e-09	70.5
rs:WP_039702831	hypothetical protein, partial [marine actinobacterium MedAcidi-G2A].	22.61	597	343	20	3	530	7	553	5e-09	70.1
rs:WP_000681439	DNA topoisomerase I [Helicobacter pylori].	23.05	642	398	24	3	614	4	579	5e-09	70.1
rs:WP_021304414	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	5e-09	70.1
rs:WP_033621297	DNA topoisomerase I [Helicobacter pylori].	23.62	470	303	13	99	537	77	521	5e-09	70.1
rs:WP_015022536	DNA topoisomerase I [Bifidobacterium asteroides].	22.38	630	378	22	2	571	6	584	5e-09	70.1
rs:WP_017443149	DNA topoisomerase I [Candidatus Rickettsia gravesii].	22.54	701	397	30	1	629	1	627	5e-09	70.1
rs:WP_000681498	DNA topoisomerase I [Helicobacter pylori].	23.05	642	398	24	3	614	4	579	5e-09	70.1
rs:WP_009092271	protein TopB, partial [Elizabethkingia anophelis].	32.31	130	74	4	274	394	1	125	5e-09	67.0
tr:R9XJX5_ASHAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.27	375	242	8	188	543	215	566	5e-09	70.1
tr:A7LH03_9HELI	SubName: Full=TopA {ECO:0000313|EMBL:ABS86823.1};	29.02	255	160	9	80	317	52	302	5e-09	70.1
rs:WP_013545113	DNA topoisomerase I [Bartonella clarridgeiae].	23.19	690	412	32	1	629	1	633	5e-09	70.1
gpu:LN483332_510	prokaryotic type i dna topoisomerase [Xanthophyllomyces dendrorhous]	22.45	637	379	29	3	577	11	594	5e-09	70.1
tr:K1RYJ4_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC48294.1}; Flags: Fragment;	31.52	165	96	7	162	319	30	184	5e-09	67.0
rs:WP_046996530	DNA topoisomerase I [Arcobacter butzleri].	23.45	563	345	22	3	533	4	512	5e-09	70.1
rs:WP_022894038	DNA topoisomerase I [Agromyces subbeticus].	22.93	641	376	21	2	571	6	599	5e-09	70.1
rs:WP_007548544	DNA topoisomerase III, partial [Listeria fleischmannii].	25.81	155	99	5	3	150	5	150	5e-09	66.2
rs:WP_015643560	topoisomerase I [Helicobacter pylori].	23.44	546	350	17	80	583	52	571	5e-09	70.1
rs:WP_000681449	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	5e-09	70.1
tr:A0A086KDL2_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	21.44	611	389	23	3	564	6	574	5e-09	69.7
rs:WP_013170872	DNA topoisomerase I [Arcanobacterium haemolyticum].	22.14	637	376	21	2	578	3	579	5e-09	70.1
rs:XP_008564435	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Galeopterus variegatus].	22.70	489	299	17	188	634	239	690	5e-09	70.1
rs:WP_035481733	hypothetical protein [Burkholderia phenoliruptrix].	29.70	202	123	5	447	629	4	205	5e-09	67.0
rs:WP_000681418	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	5e-09	70.1
rs:WP_014264447	DNA topoisomerase [Granulicella mallensis].	22.04	717	407	25	3	624	5	664	5e-09	70.1
tr:E6VVS8_DESAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.67	566	356	22	103	631	80	606	5e-09	70.1
rs:WP_016146948	hypothetical protein [Butyricicoccus pullicaecorum].	32.69	104	70	0	497	600	14	117	5e-09	66.2
rs:WP_030677905	DNA topoisomerase I [Streptomyces sp. NRRL B-1347].	22.35	595	334	23	2	530	13	545	5e-09	70.1
rs:WP_016761066	DNA topoisomerase I [Leptospira weilii].	23.95	664	398	27	3	630	4	596	5e-09	69.7
tr:T1B5Z5_9ZZZZ	SubName: Full=DNA topoisomerase III beta {ECO:0000313|EMBL:EQD65427.1}; Flags: Fragment;	31.70	224	133	8	101	312	104	319	5e-09	68.2
rs:WP_017284169	DNA topoisomerase I [Helicobacter pylori].	23.33	643	395	26	3	614	4	579	5e-09	70.1
rs:WP_032519496	DNA topoisomerase I [Prochlorococcus marinus].	23.95	430	252	13	188	572	175	574	5e-09	70.1
rs:WP_013736684	reverse gyrase [Metallosphaera cuprina].	23.11	623	335	26	3	538	611	1176	5e-09	70.1
rs:WP_002079051	DNA topoisomerase I [Leptospira interrogans].	23.56	675	387	25	3	630	4	596	5e-09	69.7
rs:WP_000681406	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	5e-09	70.1
rs:WP_021305666	DNA topoisomerase I [Helicobacter pylori].	22.79	645	396	24	3	614	4	579	5e-09	70.1
rs:WP_006197444	DNA topoisomerase I [Nodularia spumigena].	21.31	427	273	11	187	574	173	575	5e-09	70.1
rs:WP_000681427	DNA topoisomerase I [Helicobacter pylori].	23.12	640	400	25	3	614	4	579	5e-09	70.1
tr:M3LLJ8_HELPX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.86	643	398	23	3	614	4	579	5e-09	69.7
rs:WP_012912458	DNA topoisomerase I [Pirellula staleyi].	23.55	586	331	24	3	530	12	538	5e-09	70.1
rs:WP_021268964	DNA topoisomerase I [Mycobacterium abscessus].	24.83	596	328	26	2	530	3	545	5e-09	70.1
tr:M5YMY3_HELPX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.81	640	402	24	3	614	4	579	5e-09	70.1
rs:WP_046998345	DNA topoisomerase I [Arcobacter butzleri].	23.45	563	345	22	3	533	4	512	5e-09	70.1
rs:WP_015577732	DNA topoisomerase I [Streptomyces sp. PAMC26508].	22.73	396	230	11	185	530	178	547	5e-09	70.1
rs:WP_033620115	DNA topoisomerase I [Helicobacter pylori].	23.83	470	302	13	99	537	77	521	5e-09	69.7
rs:WP_022498137	DNA topoisomerase [Megasphaera elsdenii CAG:570].	21.15	676	416	23	3	630	58	664	5e-09	70.1
rs:WP_021582057	DNA topoisomerase I [Helicobacter pylori].	22.93	641	400	26	3	614	4	579	5e-09	70.1
rs:WP_013731070	DNA topoisomerase I [Verrucosispora maris].	22.48	636	373	25	2	571	9	590	5e-09	70.1
rs:WP_032582769	DNA topoisomerase III, partial [Campylobacter jejuni].	28.94	235	137	8	460	669	44	273	5e-09	68.2
rs:WP_001981236	DNA topoisomerase [Helicobacter pylori].	22.48	467	311	12	99	537	77	520	5e-09	69.7
rs:WP_037403593	DNA topoisomerase, partial [Solobacterium moorei].	35.66	129	79	2	460	587	9	134	5e-09	65.9
rs:WP_028799128	DNA topoisomerase I [Streptomyces sp. 142MFCol3.1].	22.60	593	337	21	2	530	13	547	6e-09	70.1
rs:WP_025928114	DNA topoisomerase I [Prochlorococcus sp. scB243_495G23].	24.19	430	251	14	188	572	175	574	6e-09	70.1
rs:WP_022809233	DNA topoisomerase I [Aminicenantes bacterium SCGC AAA252-K06].	22.52	666	427	23	3	641	5	608	6e-09	69.7
rs:WP_010200378	DNA topoisomerase III, partial [Pseudomonas amygdali].	31.03	116	74	2	1	115	1	111	6e-09	65.9
tr:A0A060CUD0_HELPX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AIA98715.1};	30.20	255	157	9	80	317	52	302	6e-09	69.3
rs:WP_023508056	DNA topoisomerase 1 [Rickettsia monacensis].	21.93	693	411	27	1	629	1	627	6e-09	70.1
rs:XP_010366045	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Rhinopithecus roxellana].	21.49	484	311	14	188	634	239	690	6e-09	70.1
rs:WP_030881010	DNA topoisomerase I [Streptomyces sp. NRRL B-24051].	22.73	396	230	11	185	530	178	547	6e-09	70.1
tr:G4B182_AGGAC	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGY49791.1};	39.08	87	53	0	495	581	1	87	6e-09	65.9
rs:WP_008117326	hypothetical protein, partial [[Bacteroides] pectinophilus].	32.24	152	93	6	527	674	1	146	6e-09	66.6
rs:XP_005583131	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Macaca fascicularis].	22.44	468	291	14	188	619	191	622	6e-09	70.1
rs:WP_021173921	DNA topoisomerase I [Helicobacter pylori].	29.41	255	159	8	80	317	52	302	6e-09	69.7
rs:WP_000681426	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	6e-09	69.7
tr:J0J8E7_HELPX	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EJB34022.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EJB34022.1};	22.80	465	299	12	157	583	43	485	6e-09	69.7
rs:WP_004472265	DNA topoisomerase I [Leptospira santarosai].	23.17	587	377	18	76	630	52	596	6e-09	69.7
rs:WP_009650966	DNA topoisomerase I [Campylobacter sp. FOBRC14].	22.85	674	394	24	3	629	4	598	6e-09	69.7
tr:H9Z0Q7_MACMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.44	468	291	14	188	619	239	670	6e-09	70.1
rs:WP_042630303	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	6e-09	69.7
rs:WP_030838062	DNA topoisomerase I [Streptomyces hygroscopicus].	22.33	600	335	22	2	530	14	553	6e-09	70.1
tr:H9EWR7_MACMU	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	22.44	468	291	14	188	619	239	670	6e-09	70.1
tr:E8QSG2_HELPW	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	23.83	470	302	13	99	537	80	524	6e-09	69.7
tr:A0A0E0IGT2_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA09G02300.3};	22.70	467	285	19	3	418	65	506	6e-09	70.1
rs:WP_000681451	DNA topoisomerase I [Helicobacter pylori].	22.31	650	393	23	3	614	4	579	6e-09	69.7
rs:WP_001947707	DNA topoisomerase I [Helicobacter pylori].	22.66	640	403	24	3	614	4	579	6e-09	69.7
rs:WP_025276614	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	6e-09	69.7
rs:WP_033794439	DNA topoisomerase I [Helicobacter pylori].	23.84	474	299	16	103	538	73	522	6e-09	69.7
rs:WP_000681470	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	6e-09	69.7
rs:WP_000681429	DNA topoisomerase I [Helicobacter pylori].	22.66	640	403	24	3	614	4	579	6e-09	69.7
rs:XP_012052037	DNA topoisomerase III [Cryptococcus neoformans var. grubii H99].	21.04	651	412	22	3	598	4	607	6e-09	70.1
tr:A0A078GXW6_BRANA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.42	635	405	23	3	585	12	604	6e-09	70.1
rs:WP_022406180	DNA topoisomerase [Prevotella sp. CAG:485].	23.40	453	309	13	76	520	52	474	6e-09	69.7
tr:K1T7K2_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC62380.1};	39.25	107	60	1	458	564	69	170	6e-09	66.2
rs:WP_000655378	DNA topoisomerase I [Helicobacter pylori].	29.80	255	158	9	80	317	52	302	6e-09	69.7
rs:WP_001922631	DNA topoisomerase [Helicobacter pylori].	29.80	255	158	8	80	317	52	302	6e-09	69.7
rs:WP_033611401	hypothetical protein, partial [Helicobacter pylori].	22.80	465	299	12	157	583	50	492	6e-09	69.7
tr:F9P671_STRCV	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.08	323	218	11	87	392	59	374	6e-09	69.3
sp:TOP1_RICCN	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	21.98	696	407	27	1	629	1	627	6e-09	69.7
rs:WP_034030776	hypothetical protein, partial [Pseudomonas aeruginosa].	29.20	113	74	2	1	112	1	108	6e-09	65.5
rs:WP_036204645	DNA topoisomerase I [Megasphaera elsdenii].	21.15	676	416	23	3	630	58	664	6e-09	69.7
rs:WP_000681415	DNA topoisomerase I [Helicobacter pylori].	23.05	642	398	24	3	614	4	579	6e-09	69.7
tr:A0A093XQ44_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFX94778.1};	21.98	655	416	26	3	584	6	638	6e-09	69.7
rs:WP_014016473	DNA topoisomerase I [Megasphaera elsdenii].	21.15	676	416	23	3	630	58	664	6e-09	69.7
rs:WP_018801237	DNA topoisomerase I [Salinispora arenicola].	22.80	636	371	28	2	571	9	590	6e-09	70.1
rs:WP_001956918	DNA topoisomerase I [Helicobacter pylori].	22.93	641	400	26	3	614	4	579	6e-09	69.7
tr:X1MXK9_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_L01930 {ECO:0000313|EMBL:GAI11099.1}; Flags: Fragment;	30.25	238	148	7	90	314	6	238	6e-09	67.8
tr:Q5NCT0_MOUSE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.54	482	318	13	188	634	214	665	6e-09	69.7
rs:WP_026938132	DNA topoisomerase I [Helicobacter pylori].	29.80	255	158	8	80	317	52	302	6e-09	69.7
rs:WP_033781617	DNA topoisomerase I [Helicobacter pylori].	22.66	640	403	24	3	614	4	579	6e-09	69.7
rs:WP_011390950	DNA topoisomerase I [Rhodospirillum rubrum].	21.29	700	417	24	1	629	1	637	6e-09	69.7
rs:WP_024116505	DNA topoisomerase I [Helicobacter pylori].	23.09	537	345	17	80	574	52	562	6e-09	69.7
rs:WP_035018934	DNA topoisomerase I, partial [Entomoplasma luminosum].	23.69	401	228	15	81	439	63	427	6e-09	69.7
tr:A0A0C5RM05_9MOLU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.40	645	408	21	35	629	21	616	6e-09	69.7
tr:A0A096P334_PAPAN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.44	468	291	14	188	619	239	670	6e-09	70.1
rs:XP_005583130	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Macaca fascicularis].	22.44	468	291	14	188	619	239	670	6e-09	70.1
rs:WP_011992733	DNA topoisomerase I [Campylobacter curvus].	23.15	674	392	24	3	629	4	598	6e-09	69.7
rs:WP_014687466	DNA topoisomerase I [Actinoplanes sp. SE50/110].	22.77	593	339	23	2	530	9	546	6e-09	69.7
rs:WP_025313569	DNA topoisomerase I [Helicobacter pylori].	23.17	643	396	24	3	614	4	579	6e-09	69.7
tr:A0A0B8R7W6_LISMN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.07	355	242	11	105	440	82	431	6e-09	68.9
rs:WP_017281509	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	6e-09	69.7
rs:WP_024543326	DNA topoisomerase I [actinobacterium SCGC AAA044-D11].	23.52	591	334	25	1	530	3	536	6e-09	69.7
rs:WP_037735554	DNA topoisomerase I [Streptomyces mirabilis].	22.54	599	330	22	2	530	13	547	6e-09	69.7
rs:WP_041631689	DNA topoisomerase I [Corynebacterium maris].	23.30	558	323	23	36	530	29	544	6e-09	69.7
rs:WP_005113110	MULTISPECIES: DNA topoisomerase I [Mycobacterium chelonae group].	24.83	596	328	26	2	530	3	545	6e-09	69.7
rs:WP_018675058	DNA topoisomerase I [Riemerella columbina].	24.54	546	316	22	3	523	5	479	6e-09	69.7
rs:WP_030939244	DNA topoisomerase I [Streptomyces violaceoruber].	22.20	590	343	21	2	530	13	547	6e-09	69.7
rs:WP_000681489	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	7e-09	69.7
tr:A0A0E0IGT3_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA09G02300.4};	22.70	467	285	19	3	418	65	506	7e-09	69.7
rs:WP_021672622	toprim domain protein [Prevotella sp. F0091].	33.33	135	63	5	4	117	5	133	7e-09	66.2
rs:XP_012294191	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Aotus nancymaae].	23.23	465	291	15	188	619	239	670	7e-09	69.7
rs:WP_000681422	DNA topoisomerase I [Helicobacter pylori].	22.64	658	411	24	3	630	4	593	7e-09	69.7
rs:WP_021175304	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	7e-09	69.7
tr:A0A0D4UY29_YEASX	SubName: Full=Top3p {ECO:0000313|EMBL:AJV65535.1};	22.24	670	381	28	3	576	4	629	7e-09	69.7
tr:A0A0D0UN27_CRYGA	SubName: Full=Unplaced genomic scaffold supercont1.2, whole genome shotgun sequence {ECO:0000313|EMBL:KIR49543.1};	21.23	650	412	23	3	598	4	607	7e-09	69.7
rs:WP_033616372	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	7e-09	69.7
rs:XP_008091224	DNA topoisomerase [Colletotrichum graminicola M1.001].	22.14	560	355	20	3	521	4	523	7e-09	69.7
rs:WP_020175813	DNA topoisomerase I [Methyloferula stellata].	22.83	692	411	31	1	629	1	632	7e-09	69.7
tr:M1BDQ9_SOLTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.59	301	204	7	295	589	1	278	7e-09	69.3
rs:XP_008807900	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Phoenix dactylifera].	21.97	437	285	15	3	396	13	436	7e-09	69.7
tr:A0A0B2RG64_GLYSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.73	376	239	12	64	406	228	592	7e-09	69.3
rs:WP_040176353	DNA topoisomerase III, partial [Klebsiella pneumoniae].	26.62	278	136	10	461	673	1	275	7e-09	67.8
rs:WP_019478497	DNA topoisomerase I [Prochlorococcus sp. W8].	23.22	422	265	12	188	572	175	574	7e-09	69.7
rs:WP_000655375	DNA topoisomerase I [Helicobacter pylori].	29.80	255	158	8	80	317	52	302	7e-09	69.7
rs:WP_000681524	DNA topoisomerase I [Helicobacter pylori].	22.87	647	393	23	3	614	4	579	7e-09	69.7
rs:WP_033756459	DNA topoisomerase I [Helicobacter pylori].	23.29	468	307	12	99	537	77	521	7e-09	69.3
rs:WP_031755974	DNA topoisomerase I [Pseudomonas aeruginosa].	21.05	627	355	22	74	641	59	604	7e-09	69.3
rs:WP_001981450	DNA topoisomerase I [Helicobacter pylori].	22.86	643	398	25	3	614	4	579	7e-09	69.7
tr:A0A086JJZ8_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.42	607	386	23	3	560	6	570	7e-09	69.3
rs:WP_028849756	DNA topoisomerase I [Thermocrispum municipale].	24.49	588	331	25	2	530	15	548	7e-09	69.7
rs:XP_003378698	DNA topoisomerase 3-alpha [Trichinella spiralis].	21.09	403	267	8	188	573	207	575	7e-09	69.7
rs:WP_022802495	DNA topoisomerase I [Deinococcus sp. 2009].	25.72	381	214	12	189	533	173	520	7e-09	69.3
rs:WP_015178581	DNA topoisomerase I [Oscillatoria nigro-viridis].	23.36	578	340	19	3	530	4	528	7e-09	69.7
tr:M3QQR9_HELPX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.59	642	401	23	3	614	4	579	7e-09	69.7
rs:WP_046655876	DNA topoisomerase I [Helicobacter pylori].	22.81	640	402	24	3	614	4	579	7e-09	69.7
rs:WP_002872293	DNA topoisomerase I [Campylobacter jejuni].	23.01	652	394	25	3	618	5	584	7e-09	69.7
tr:L8VSL9_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	23.11	476	298	12	99	537	80	524	7e-09	69.3
rs:WP_001918750	DNA topoisomerase I [Helicobacter pylori].	23.05	642	398	24	3	614	4	579	7e-09	69.7
rs:WP_022576817	hypothetical protein, partial [Helicobacter pylori].	32.00	175	105	4	157	317	43	217	7e-09	66.6
rs:WP_020104497	DNA topoisomerase I [Mycoplasma hyorhinis].	22.59	664	403	25	2	629	8	596	7e-09	69.3
rs:WP_001066146	DNA topoisomerase I [Helicobacter pylori].	23.87	465	294	15	157	583	128	570	7e-09	69.3
rs:WP_000681465	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	7e-09	69.7
rs:WP_000681442	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	7e-09	69.7
rs:WP_040154376	hypothetical protein [Klebsiella pneumoniae].	26.53	147	100	2	475	614	1	146	7e-09	66.6
rs:WP_027895073	DNA topoisomerase I [Megasphaera elsdenii].	21.35	679	411	24	3	630	58	664	7e-09	69.7
rs:WP_000681529	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	7e-09	69.7
rs:WP_002873255	DNA topoisomerase I [Campylobacter jejuni].	22.09	652	400	23	3	618	5	584	7e-09	69.3
rs:WP_000681452	DNA topoisomerase I [Helicobacter pylori].	23.12	640	400	25	3	614	4	579	7e-09	69.7
rs:WP_002805396	DNA topoisomerase I [Prochlorococcus marinus].	24.07	432	249	15	188	572	175	574	7e-09	69.7
rs:WP_042636148	DNA topoisomerase I [Helicobacter pylori].	22.98	470	306	14	99	537	77	521	7e-09	69.3
rs:WP_001920473	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	7e-09	69.7
rs:WP_000681414	DNA topoisomerase I [Helicobacter pylori].	23.05	642	398	24	3	614	4	579	7e-09	69.7
rs:WP_000681407	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	7e-09	69.7
rs:WP_046294178	DNA topoisomerase I [Mycobacterium sp. UM_Kg17].	23.38	633	372	23	2	571	19	601	7e-09	69.7
rs:WP_032821588	topoisomerase I, partial [Oenococcus oeni].	29.80	151	86	4	261	399	42	184	7e-09	66.6
rs:WP_025449283	DNA topoisomerase I [Helicobacter pylori].	23.11	476	298	12	99	537	77	521	7e-09	69.3
rs:WP_030367305	DNA topoisomerase I [Streptomyces roseoverticillatus].	22.18	595	339	22	2	530	13	549	7e-09	69.7
rs:XP_008008772	PREDICTED: DNA topoisomerase 3-alpha [Chlorocebus sabaeus].	22.44	468	291	14	188	619	239	670	7e-09	69.7
rs:XP_002923167	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha [Ailuropoda melanoleuca].	22.79	487	301	17	188	634	239	690	7e-09	69.7
rs:WP_033591175	DNA topoisomerase I [Helicobacter pylori].	23.46	520	337	16	103	583	13	510	7e-09	69.3
rs:WP_002894594	DNA topoisomerase I [Campylobacter jejuni].	22.85	652	395	25	3	618	5	584	7e-09	69.3
rs:WP_018225554	DNA topoisomerase I [actinobacterium SCGC AAA044-N04].	23.85	587	335	24	1	530	9	540	7e-09	69.7
rs:WP_033363230	DNA topoisomerase I [Dactylosporangium aurantiacum].	22.97	640	362	25	2	571	9	587	7e-09	69.7
rs:WP_018731280	DNA topoisomerase I [Salinispora pacifica].	22.33	636	374	25	2	571	9	590	7e-09	69.7
rs:WP_039082230	DNA topoisomerase I [Helicobacter pylori].	23.05	642	398	24	3	614	4	579	7e-09	69.3
rs:WP_015428573	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	7e-09	69.3
rs:WP_000054707	DNA topoisomerase I [Leptospira interrogans].	24.04	678	380	25	3	630	4	596	7e-09	69.3
tr:A0A0D4VXN5_YEASX	SubName: Full=Top3p {ECO:0000313|EMBL:AJV77519.1};	22.24	670	381	28	3	576	4	629	7e-09	69.3
tr:J0U2N3_HELPX	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EJC54786.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EJC54786.1};	29.57	230	147	5	103	317	73	302	7e-09	68.2
rs:WP_024623694	DNA topoisomerase I [Lactobacillus fabifermentans].	22.45	579	379	23	90	635	96	637	7e-09	69.3
rs:WP_046189722	DNA topoisomerase I [Mycobacterium arupense].	23.38	633	372	23	2	571	19	601	7e-09	69.7
rs:WP_000681424	DNA topoisomerase I [Helicobacter pylori].	22.87	647	393	24	3	614	4	579	7e-09	69.3
rs:WP_008840962	DNA topoisomerase I [Pediococcus lolii].	21.44	569	384	18	90	629	70	604	7e-09	69.3
rs:WP_000681472	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	7e-09	69.3
rs:WP_004778509	DNA topoisomerase I [Leptospira kirschneri].	23.89	678	377	28	3	630	4	592	8e-09	69.3
tr:A0A016QU65_9DEIO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.05	590	337	23	4	530	1	536	8e-09	69.7
rs:WP_002917004	DNA topoisomerase I, partial [Campylobacter jejuni].	22.09	652	400	23	3	618	5	584	8e-09	69.3
rs:WP_034038052	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	25.15	167	117	4	1	165	1	161	8e-09	65.9
rs:WP_037911842	DNA topoisomerase I [Streptomyces yeochonensis].	23.33	600	327	24	2	530	13	550	8e-09	69.7
tr:A0A090SJ58_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL27765.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL27765.1};	27.35	223	136	8	433	637	30	244	8e-09	67.0
rs:XP_012294192	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Aotus nancymaae].	23.23	465	291	15	188	619	156	587	8e-09	69.7
rs:WP_005268646	DNA topoisomerase I [Arthrobacter crystallopoietes].	22.00	591	359	22	2	538	12	554	8e-09	69.7
rs:WP_018226836	DNA topoisomerase I [actinobacterium SCGC AAA023-D18].	22.64	592	333	24	2	530	4	533	8e-09	69.7
rs:WP_024667726	hypothetical protein, partial [Pseudomonas syringae].	30.17	116	75	2	1	115	1	111	8e-09	65.5
rs:WP_018738512	DNA topoisomerase I [Salinispora pacifica].	22.48	636	373	26	2	571	9	590	8e-09	69.7
rs:WP_019869566	DNA topoisomerase I [Salinispora pacifica].	22.17	636	375	25	2	571	9	590	8e-09	69.7
rs:WP_026324925	DNA topoisomerase I [Salinispora pacifica].	22.48	636	373	26	2	571	9	590	8e-09	69.7
rs:WP_033753531	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	8e-09	69.3
tr:Q3V3P1_MOUSE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.54	482	318	13	188	634	239	690	8e-09	69.7
rs:WP_018489446	DNA topoisomerase I [Streptomyces sp. CcalMP-8W].	21.79	592	345	20	2	530	13	549	8e-09	69.7
rs:WP_002878738	DNA topoisomerase I [Campylobacter jejuni].	22.09	652	400	23	3	618	5	584	8e-09	69.3
rs:WP_001897195	DNA topoisomerase I [Helicobacter pylori].	23.24	469	305	14	99	537	77	520	8e-09	69.3
rs:WP_004483035	DNA topoisomerase I [Leptospira santarosai].	23.50	583	380	19	76	630	52	596	8e-09	69.3
rs:WP_034086253	DNA topoisomerase I [Pseudomonas aeruginosa].	21.47	517	289	18	74	537	59	511	8e-09	69.3
rs:WP_033589834	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	8e-09	69.3
rs:XP_008022021	hypothetical protein SETTUDRAFT_102706 [Setosphaeria turcica Et28A].	20.97	558	364	19	3	520	5	525	8e-09	69.3
rs:WP_041721132	hypothetical protein [Alkaliphilus metalliredigens].	35.71	98	49	3	1	93	1	89	8e-09	64.7
rs:XP_010814336	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Bos taurus].	21.84	490	301	17	188	634	239	689	8e-09	69.7
tr:J6YG14_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJX60934.1};	28.96	183	114	6	500	667	3	184	8e-09	66.2
rs:WP_001972760	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	8e-09	69.3
rs:WP_002207369	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	8e-09	69.3
rs:WP_000681513	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	23	3	614	4	579	8e-09	69.3
rs:WP_034216741	MULTISPECIES: DNA topoisomerase I [Arcobacter].	24.39	574	326	24	3	533	4	512	8e-09	69.3
rs:WP_033420432	DNA topoisomerase I, partial [Nesterenkonia alba].	22.09	584	351	22	2	530	5	539	8e-09	69.3
rs:WP_001952760	DNA topoisomerase I [Helicobacter pylori].	22.93	641	400	26	3	614	4	579	8e-09	69.3
sp:TOP3_YEAST	RecName: Full=DNA topoisomerase 3; EC=5.99.1.2; AltName: Full=DNA topoisomerase III;	22.24	670	381	28	3	576	4	629	8e-09	69.3
rs:WP_033613056	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	8e-09	69.3
rs:WP_025967891	DNA topoisomerase I [Prochlorococcus sp. scB245a_518I6].	25.38	327	207	10	261	572	270	574	8e-09	69.3
tr:A0A0E0A850_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OGLUM06G11680.1};	27.31	260	161	9	64	303	339	590	8e-09	69.7
rs:WP_021306574	DNA topoisomerase I [Helicobacter pylori].	23.13	709	408	29	3	636	4	650	8e-09	69.3
tr:A0A060CUT7_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	23.53	476	296	13	99	537	77	521	8e-09	69.3
rs:WP_024493786	DNA topoisomerase I [Streptomyces sp. AW19M42].	22.03	590	346	21	2	530	13	549	8e-09	69.7
tr:A0A094CT68_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY57194.1};	21.83	655	417	26	3	584	6	638	8e-09	69.3
tr:R9L3G1_9FIRM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOS53210.1};	48.44	64	33	0	145	208	10	73	8e-09	64.3
rs:WP_001939020	DNA topoisomerase I [Helicobacter pylori].	22.22	639	407	22	3	614	4	579	8e-09	69.3
tr:K2CJS5_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	27.86	341	182	11	3	314	4	309	8e-09	68.6
rs:WP_002918791	DNA topoisomerase I [Campylobacter jejuni].	22.09	652	400	23	3	618	5	584	8e-09	69.3
rs:WP_008746511	DNA topoisomerase I [Streptomyces sp. SPB74].	22.61	597	331	23	2	530	13	546	8e-09	69.3
tr:K1TKN5_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC68124.1}; Flags: Fragment;	35.71	98	61	2	492	588	3	99	8e-09	65.9
rs:WP_030334236	DNA topoisomerase I [Micromonospora parva].	22.52	635	374	25	2	571	9	590	8e-09	69.3
rs:WP_006707234	DNA topoisomerase I, partial [Candidatus Regiella insecticola].	22.20	491	292	17	187	633	199	643	8e-09	69.3
rs:WP_041224044	hypothetical protein, partial [Deferribacter desulfuricans].	26.02	415	246	18	3	396	5	379	8e-09	68.9
rs:WP_018390664	DNA topoisomerase I [Ancylobacter sp. FA202].	22.24	688	420	29	1	629	1	632	8e-09	69.3
tr:S9XBD7_9CETA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.78	492	294	20	188	620	193	662	8e-09	69.3
tr:A0A0B7A5F1_9EUPU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.08	494	291	19	188	634	230	681	8e-09	69.3
rs:WP_030486310	DNA topoisomerase I [Micromonospora chokoriensis].	22.57	638	370	26	2	571	9	590	8e-09	69.3
tr:A0A0C2F085_9PEZI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KIH92199.1};	21.36	557	375	17	3	526	5	531	8e-09	69.3
tr:A0A0E0HP22_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA06G12620.1};	27.31	260	161	9	64	303	339	590	9e-09	69.7
rs:WP_000681419	DNA topoisomerase I [Helicobacter pylori].	22.86	643	398	23	3	614	4	579	9e-09	69.3
rs:WP_000277562	DNA topoisomerase I [Helicobacter pylori].	22.86	468	309	12	99	537	77	521	9e-09	69.3
tr:F0U7D2_AJEC8	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.76	442	289	16	3	409	6	434	9e-09	68.6
rs:WP_033756263	DNA topoisomerase I [Helicobacter pylori].	23.76	543	346	18	83	583	55	571	9e-09	69.3
tr:D1NFZ9_HAEIF	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFA28256.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFA28256.1}; Flags: Fragment;	32.43	148	74	4	161	282	7	154	9e-09	67.4
tr:A0A076ETH3_RHOOP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.64	592	339	22	2	530	21	556	9e-09	69.3
rs:WP_031275716	DNA topoisomerase I [Pseudomonas aeruginosa].	21.05	627	355	22	74	641	59	604	9e-09	68.9
tr:C0XU91_9CORY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.54	542	324	21	36	530	38	541	9e-09	69.3
rs:WP_031246870	DNA topoisomerase I, partial [Helicobacter pylori].	29.53	254	158	9	81	317	53	302	9e-09	67.4
tr:E8ZK73_MYCHL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00003390}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.83	591	385	16	83	630	66	622	9e-09	69.3
rs:WP_001920978	DNA topoisomerase [Helicobacter pylori].	23.19	470	305	13	99	537	77	521	9e-09	68.9
rs:XP_002617565	hypothetical protein CLUG_03009 [Clavispora lusitaniae ATCC 42720].	23.58	598	357	25	3	544	4	557	9e-09	68.9
rs:WP_044261765	DNA topoisomerase I [Campylobacter jejuni].	22.85	652	395	25	3	618	5	584	9e-09	69.3
rs:WP_036851281	DNA topoisomerase I [Porphyromonas cangingivalis].	22.30	538	338	18	3	523	5	479	9e-09	69.3
rs:WP_022470161	DNA topoisomerase III [Bacteroides thetaiotaomicron CAG:40].	25.37	201	140	5	244	438	6	202	9e-09	66.6
rs:WP_046280474	DNA topoisomerase I, partial [Limnoraphis robusta].	26.02	269	164	10	273	530	16	260	9e-09	68.9
rs:WP_024750697	DNA topoisomerase I [Helicobacter pylori].	23.29	468	307	11	99	537	77	521	9e-09	68.9
rs:XP_008227548	PREDICTED: DNA topoisomerase 3-alpha [Prunus mume].	21.81	651	383	28	3	585	4	596	9e-09	69.3
rs:WP_012691439	DNA topoisomerase I [Rhodococcus opacus].	22.64	592	339	21	2	530	21	556	9e-09	69.3
rs:WP_033610393	DNA topoisomerase I [Lactobacillus paraplantarum].	22.47	583	375	23	90	635	95	637	9e-09	69.3
rs:WP_033786383	DNA topoisomerase I [Helicobacter pylori].	22.66	640	403	24	3	614	4	579	9e-09	69.3
rs:WP_008580070	MULTISPECIES: DNA topoisomerase I [Rickettsia].	21.81	697	407	28	1	629	1	627	9e-09	69.3
rs:WP_002922085	DNA topoisomerase I [Campylobacter jejuni].	22.24	652	399	23	3	618	5	584	9e-09	69.3
rs:WP_024544176	DNA topoisomerase I [Mycoplasma salivarium].	23.66	655	388	27	38	646	24	612	9e-09	68.9
rs:WP_033597953	DNA topoisomerase I [Helicobacter pylori].	23.40	470	304	14	99	537	77	521	9e-09	68.9
rs:WP_024446927	DNA topoisomerase I [Mycobacterium iranicum].	23.28	597	333	24	2	530	16	555	9e-09	69.3
rs:WP_043079487	DNA topoisomerase I [Mycobacterium immunogenum].	24.75	590	330	25	2	530	3	539	9e-09	69.3
rs:WP_002831689	DNA topoisomerase I [Pediococcus acidilactici].	21.44	569	384	18	90	629	70	604	9e-09	69.3
rs:WP_004493941	DNA topoisomerase I [Leptospira santarosai].	23.00	661	408	24	3	630	4	596	9e-09	68.9
rs:XP_008564436	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Galeopterus variegatus].	22.70	489	299	17	188	634	52	503	9e-09	69.3
rs:WP_001953097	DNA topoisomerase I [Helicobacter pylori].	22.66	640	403	24	3	614	4	579	9e-09	69.3
tr:I6F9E1_SHIBO	SubName: Full=Topoisomerase DNA binding C4 zinc finger family protein {ECO:0000313|EMBL:EIQ52883.1};	29.91	117	75	1	494	610	1	110	9e-09	65.5
rs:WP_002869687	DNA topoisomerase I [Campylobacter jejuni].	22.09	652	400	23	3	618	5	584	9e-09	69.3
rs:XP_008060813	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Tarsius syrichta].	22.22	486	305	17	188	634	144	595	9e-09	69.3
rs:WP_040156985	DNA topoisomerase I [Helicobacter pylori].	23.44	465	296	15	157	583	128	570	9e-09	68.9
tr:V6LCA0_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	23.46	520	337	16	103	583	41	538	9e-09	68.9
rs:WP_044344627	hypothetical protein, partial [Pseudomonas meliae].	22.08	643	401	21	2	616	3	573	9e-09	68.9
rs:XP_011817025	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Colobus angolensis palliatus].	22.13	488	303	15	188	634	239	690	9e-09	69.3
rs:WP_033604261	DNA topoisomerase I [Helicobacter pylori].	23.62	470	303	13	99	537	77	521	9e-09	68.9
rs:WP_028678127	DNA topoisomerase I [Salinispora arenicola].	22.80	636	371	27	2	571	9	590	9e-09	69.3
rs:WP_000054710	DNA topoisomerase I [Leptospira interrogans].	23.82	676	384	24	3	630	4	596	9e-09	68.9
rs:WP_040422144	DNA topoisomerase I [Corynebacterium lipophiloflavum].	24.54	542	324	21	36	530	29	532	9e-09	69.3
rs:WP_046872095	hypothetical protein [Pediococcus damnosus].	32.59	135	85	2	189	317	3	137	9e-09	65.5
rs:WP_002205547	DNA topoisomerase I [Helicobacter pylori].	22.86	468	309	12	99	537	77	521	9e-09	68.9
rs:WP_036060849	DNA topoisomerase I [Leptospira weilii].	23.90	657	407	26	3	630	4	596	9e-09	68.9
rs:XP_005706261	DNA topoisomerase III alpha [Galdieria sulphuraria].	23.12	398	252	13	188	560	235	603	9e-09	68.9
rs:WP_002932097	DNA topoisomerase I [Campylobacter jejuni].	22.24	652	399	23	3	618	5	584	9e-09	68.9
rs:WP_002867521	DNA topoisomerase I [Campylobacter jejuni].	22.09	652	400	23	3	618	5	584	1e-08	68.9
rs:WP_001931410	DNA topoisomerase [Helicobacter pylori].	23.66	465	295	15	157	583	128	570	1e-08	68.9
rs:WP_001892407	DNA topoisomerase I [Helicobacter pylori].	23.19	470	305	14	99	537	77	521	1e-08	68.9
rs:WP_000277576	DNA topoisomerase I [Helicobacter pylori].	22.98	470	306	14	99	537	77	521	1e-08	68.9
rs:WP_001877663	DNA topoisomerase I [Helicobacter pylori].	23.08	468	308	11	99	537	77	521	1e-08	68.9
rs:WP_002899161	DNA topoisomerase I [Campylobacter jejuni].	22.09	652	400	23	3	618	5	584	1e-08	68.9
rs:XP_006457247	hypothetical protein AGABI2DRAFT_154568 [Agaricus bisporus var. bisporus H97].	22.07	598	387	20	3	557	4	565	1e-08	68.9
rs:WP_014660517	DNA topoisomerase I [Helicobacter cetorum].	22.87	704	401	31	3	629	4	642	1e-08	68.9
tr:A0A0E0PWE4_ORYRU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ORUFI06G11430.1};	22.94	571	319	23	100	583	376	912	1e-08	69.3
rs:WP_019382431	hypothetical protein [Bacillus oceanisediminis].	34.26	108	59	4	3	105	4	104	1e-08	64.7
rs:WP_012539201	DNA topoisomerase I [Borrelia recurrentis].	23.98	588	336	25	77	604	69	605	1e-08	69.3
rs:WP_044573128	DNA topoisomerase I [Streptomyces iranensis].	22.64	592	339	23	2	530	14	549	1e-08	69.3
rs:WP_033745323	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	1e-08	68.9
tr:H2YRK8_CIOSA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.49	315	206	8	256	560	334	623	1e-08	68.9
rs:WP_015085618	topoisomerase I [Helicobacter pylori].	29.41	255	159	8	80	317	52	302	1e-08	68.9
rs:WP_033754862	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	1e-08	68.9
rs:WP_000681450	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	1e-08	68.9
tr:A0A078SM90_9PORP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.88	459	308	11	76	520	46	472	1e-08	68.9
tr:S5SRZ9_9CORY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.30	558	323	23	36	530	17	532	1e-08	69.3
rs:WP_004474620	DNA topoisomerase I [Leptospira santarosai].	23.50	583	380	19	76	630	52	596	1e-08	68.9
rs:XP_010270299	PREDICTED: DNA topoisomerase 3-alpha [Nelumbo nucifera].	22.29	646	385	24	3	585	10	601	1e-08	69.3
tr:A0A023GLY9_9ACAR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.53	395	247	13	188	560	249	606	1e-08	68.9
tr:W6TIV2_9SPIO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.75	466	262	19	188	604	97	527	1e-08	68.9
rs:WP_013537659	reverse gyrase [Thermovibrio ammonificans].	22.35	528	325	16	80	579	710	1180	1e-08	69.3
rs:XP_004932606	PREDICTED: DNA topoisomerase 3-alpha-like [Bombyx mori].	24.68	539	317	23	46	560	89	562	1e-08	69.3
tr:A0A0E0CKE9_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OMERI02G16280.8};	22.24	625	352	27	39	610	310	853	1e-08	69.3
rs:WP_000681491	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	1e-08	68.9
rs:WP_037702547	DNA topoisomerase I [Streptomyces scabiei].	22.39	594	337	21	2	530	13	547	1e-08	69.3
rs:WP_025366675	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	1e-08	68.9
rs:WP_000681464	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	1e-08	68.9
rs:WP_000054706	DNA topoisomerase I [Leptospira interrogans].	23.56	675	387	25	3	630	4	596	1e-08	68.9
rs:WP_002131796	DNA topoisomerase I [Leptospira interrogans].	23.56	675	387	25	3	630	4	596	1e-08	68.9
rs:WP_000655381	DNA topoisomerase I [Helicobacter pylori].	30.17	232	143	6	103	317	73	302	1e-08	68.9
rs:WP_017282916	DNA topoisomerase I [Helicobacter pylori].	22.71	643	399	25	3	614	4	579	1e-08	68.9
rs:WP_000681462	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	1e-08	68.9
rs:WP_011667572	DNA topoisomerase I [Lactobacillus brevis].	21.51	595	373	23	88	635	78	625	1e-08	68.9
tr:A0A085MJL8_9BILA	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	24.62	394	241	18	188	560	214	572	1e-08	69.3
rs:WP_033737420	DNA topoisomerase I [Helicobacter pylori].	23.28	537	344	17	80	574	52	562	1e-08	68.9
rs:NP_001071443	DNA topoisomerase 3-alpha [Bos taurus].	22.47	494	293	18	188	634	239	689	1e-08	69.3
rs:WP_001873428	DNA topoisomerase I [Helicobacter pylori].	22.65	468	310	12	99	537	77	521	1e-08	68.9
rs:WP_021897169	DNA topoisomerase TopA [Prevotella sp. CAG:924].	24.44	405	247	11	3	392	15	375	1e-08	68.9
tr:C2D5U8_LACBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.80	151	86	4	261	399	18	160	1e-08	65.9
rs:WP_001924354	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	1e-08	68.9
rs:WP_042373481	DNA topoisomerase I [Streptacidiphilus neutrinimicus].	22.96	601	337	24	2	530	13	559	1e-08	68.9
rs:WP_017279968	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	1e-08	68.9
rs:WP_036735514	DNA topoisomerase III, partial [Paenibacillus zanthoxyli].	33.61	122	76	2	497	618	20	136	1e-08	65.5
rs:WP_001972196	DNA topoisomerase I [Helicobacter pylori].	23.33	643	395	26	3	614	4	579	1e-08	68.9
rs:XP_006601079	PREDICTED: DNA topoisomerase 3-alpha-like isoform X5 [Glycine max].	23.33	510	317	19	64	527	304	785	1e-08	68.9
tr:A0A0A1SUL0_9HYPO	SubName: Full=Putative DNA topoisomerase 3 {ECO:0000313|EMBL:CEJ81921.1};	21.72	557	359	19	3	520	55	573	1e-08	68.9
rs:XP_010366052	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Rhinopithecus roxellana].	22.13	488	303	15	188	634	156	607	1e-08	68.9
sp:TOP1_HELPJ	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	23.05	642	398	26	3	614	4	579	1e-08	68.9
sp:TOP3A_MOUSE	RecName: Full=DNA topoisomerase 3-alpha; EC=5.99.1.2; AltName: Full=DNA topoisomerase III alpha;	20.54	482	318	13	188	634	239	690	1e-08	68.9
rs:WP_000054711	DNA topoisomerase I [Leptospira interrogans].	23.56	675	387	25	3	630	4	596	1e-08	68.6
rs:WP_000681460	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	1e-08	68.9
rs:XP_003958728	hypothetical protein KAFR_0H01830 [Kazachstania africana CBS 2517].	22.34	667	383	26	3	576	4	628	1e-08	68.9
rs:XP_773035	hypothetical protein CNBJ3110 [Cryptococcus neoformans var. neoformans B-3501A].	21.35	651	410	22	3	598	4	607	1e-08	68.9
rs:WP_028269930	DNA topoisomerase I [Arthrobacter sp. UNC362MFTsu5.1].	21.73	589	362	20	2	538	10	551	1e-08	68.9
rs:WP_022866500	DNA topoisomerase I [Actinobaculum urinale].	22.77	584	347	20	2	530	3	537	1e-08	68.9
rs:WP_015904582	DNA topoisomerase I [Desulfobacterium autotrophicum].	21.77	634	404	26	38	630	24	606	1e-08	68.9
rs:WP_033619145	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	1e-08	68.9
rs:WP_012007264	DNA topoisomerase I [Prochlorococcus marinus].	23.95	430	252	14	188	572	175	574	1e-08	68.9
rs:WP_046835583	DNA topoisomerase III, partial [Pseudomonas amygdali].	29.31	116	72	3	1	113	1	109	1e-08	64.7
rs:WP_042633138	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	1e-08	68.9
rs:WP_000681400	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	1e-08	68.9
rs:WP_009255105	hypothetical protein [Lachnospiraceae bacterium 3_1_57FAA_CT1].	29.73	185	117	5	497	671	17	198	1e-08	65.9
rs:WP_020984932	DNA topoisomerase I [Leptospira alexanderi].	23.64	664	402	24	3	630	4	598	1e-08	68.6
rs:WP_002937473	DNA topoisomerase I [Campylobacter jejuni].	22.09	652	400	23	3	618	5	584	1e-08	68.9
rs:WP_045677419	DNA topoisomerase I [Desulfatitalea sp. BRH_c12].	22.70	599	384	23	83	640	61	621	1e-08	68.9
tr:F1MGY1_BOVIN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.47	494	293	18	188	634	239	689	1e-08	68.9
rs:WP_002105176	DNA topoisomerase I [Leptospira interrogans].	23.56	675	387	25	3	630	4	596	1e-08	68.6
rs:WP_025478161	DNA topoisomerase I [Enterococcus faecium].	25.52	572	349	26	103	635	81	614	1e-08	68.9
rs:WP_045254282	DNA topoisomerase I [Microbacterium foliorum].	21.93	611	328	22	2	538	6	541	1e-08	68.9
rs:WP_017863681	DNA topoisomerase I [Leptospira santarosai].	22.80	592	373	19	76	630	52	596	1e-08	68.6
rs:WP_011596786	MULTISPECIES: DNA topoisomerase I [Rhodococcus].	22.80	592	338	21	2	530	21	556	1e-08	68.9
rs:WP_000681398	DNA topoisomerase I [Helicobacter pylori].	22.50	640	404	24	3	614	4	579	1e-08	68.9
rs:WP_017731204	hypothetical protein [Nafulsella turpanensis].	25.25	408	258	14	1	400	1	369	1e-08	68.9
rs:WP_002759875	DNA topoisomerase I [Leptospira borgpetersenii].	24.10	585	368	19	79	630	56	597	1e-08	68.6
rs:WP_029125058	DNA topoisomerase I [Salinispora pacifica].	22.17	636	375	25	2	571	9	590	1e-08	68.9
rs:WP_018743856	DNA topoisomerase I [Salinispora pacifica].	22.17	636	375	25	2	571	9	590	1e-08	68.9
rs:WP_002908846	DNA topoisomerase I [Campylobacter jejuni].	22.09	652	400	23	3	618	5	584	1e-08	68.9
rs:WP_001903770	DNA topoisomerase I [Helicobacter pylori].	22.65	468	310	11	99	537	77	521	1e-08	68.6
rs:WP_016884539	DNA topoisomerase I [Rhodococcus sp. DK17].	22.80	592	338	21	2	530	21	556	1e-08	68.9
rs:WP_025567201	MULTISPECIES: DNA topoisomerase I [Deinococcus].	23.64	588	333	23	3	530	10	541	1e-08	68.9
rs:WP_011578289	DNA topoisomerase I [Helicobacter acinonychis].	23.21	642	397	24	3	614	4	579	1e-08	68.9
rs:WP_027660605	DNA topoisomerase I [Salinispora pacifica].	22.17	636	375	25	2	571	9	590	1e-08	68.9
tr:A0A0D4UDT0_YEASX	SubName: Full=Top3p {ECO:0000313|EMBL:AJV58868.1};	22.24	670	381	28	3	576	4	629	1e-08	68.6
rs:WP_018720741	DNA topoisomerase I [Salinispora pacifica].	22.17	636	375	25	2	571	9	590	1e-08	68.9
rs:WP_000681423	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	1e-08	68.9
rs:WP_026095613	DNA topoisomerase I [Microbacterium sp. B19].	22.61	597	345	24	2	538	6	545	1e-08	68.9
tr:G7PTT8_MACFA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.44	468	291	14	188	619	77	508	1e-08	68.9
rs:XP_011830673	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Mandrillus leucophaeus].	22.44	468	291	14	188	619	239	670	1e-08	68.9
tr:Q48NI0_PSE14	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AAZ34932.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AAZ34932.1};	31.03	116	74	2	1	115	1	111	1e-08	68.2
tr:I9R4T3_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.74	232	144	7	103	317	73	302	1e-08	68.2
tr:D3PEJ4_DEFDS	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:BAI81636.1};	26.02	415	246	18	3	396	5	379	1e-08	68.6
rs:WP_046736800	DNA topoisomerase I [Dehalogenimonas sp. WBC-2].	23.01	665	397	29	2	618	6	603	1e-08	68.6
tr:Q71HR1_LACDL	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:AAQ07227.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AAQ07227.1}; Flags: Fragment;	32.35	102	67	1	482	581	2	103	1e-08	64.7
rs:WP_038417165	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	1e-08	68.9
rs:WP_001935335	DNA topoisomerase I [Helicobacter pylori].	22.86	643	398	25	3	614	4	579	1e-08	68.9
tr:M6Q9F4_9LEPT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.90	657	407	26	3	630	5	597	1e-08	68.6
tr:A0A0D4U5M3_YEASX	SubName: Full=Top3p {ECO:0000313|EMBL:AJV55256.1};	22.09	670	382	28	3	576	4	629	1e-08	68.6
rs:WP_043615263	DNA topoisomerase I [Nonomuraea candida].	22.19	649	353	24	36	591	17	606	1e-08	68.9
rs:WP_000655373	DNA topoisomerase I [Helicobacter pylori].	23.42	491	321	18	80	538	52	519	1e-08	68.6
rs:XP_006601078	PREDICTED: DNA topoisomerase 3-alpha-like isoform X4 [Glycine max].	23.33	510	317	19	64	527	302	783	1e-08	68.9
rs:WP_022557734	MULTISPECIES: hypothetical protein [Xanthomonas].	32.81	128	76	3	276	393	3	130	1e-08	65.5
tr:K2CKH4_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.25	764	426	28	3	677	4	688	1e-08	68.6
tr:T1AKL2_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD61116.1}; Flags: Fragment;	31.65	139	85	4	272	403	1	136	1e-08	65.5
tr:A0A0D4UBD9_YEASX	SubName: Full=Top3p {ECO:0000313|EMBL:AJV57967.1};	22.24	670	381	28	3	576	4	629	1e-08	68.6
rs:WP_015644696	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	1e-08	68.6
rs:XP_011104558	top3p [Saccharomyces arboricola H-6].	22.04	667	385	23	3	576	4	628	1e-08	68.6
rs:WP_010679545	DNA topoisomerase I [Leptospira interrogans].	23.56	675	387	25	3	630	4	596	1e-08	68.6
rs:WP_011990971	DNA topoisomerase I [Campylobacter jejuni].	22.24	652	399	23	3	618	5	584	1e-08	68.6
rs:WP_000681485	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	1e-08	68.6
rs:WP_030633085	DNA topoisomerase I [Streptomyces albus].	21.74	598	338	20	2	530	13	549	1e-08	68.9
tr:A0A0D4TTY4_YEASX	SubName: Full=Top3p {ECO:0000313|EMBL:AJV51674.1};	22.24	670	381	28	3	576	4	629	1e-08	68.6
rs:WP_039327136	hypothetical protein [Candidatus Saccharibacteria oral taxon TM7x].	24.47	380	233	9	157	522	137	476	1e-08	68.9
rs:WP_001956342	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	1e-08	68.6
rs:WP_000681457	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	1e-08	68.6
rs:WP_000681399	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	1e-08	68.6
rs:WP_027657238	DNA topoisomerase I [Salinispora pacifica].	22.17	636	375	25	2	571	9	590	1e-08	68.9
rs:WP_011141022	DNA topoisomerase I [Gloeobacter violaceus].	22.42	571	338	19	103	614	84	608	1e-08	68.6
rs:XP_003809826	PREDICTED: DNA topoisomerase 3-alpha [Pan paniscus].	22.13	488	303	15	188	634	239	690	1e-08	68.9
rs:XP_003279918	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Nomascus leucogenys].	22.24	490	300	16	188	634	239	690	1e-08	68.9
rs:WP_000681526	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	1e-08	68.6
rs:WP_029635562	DNA topoisomerase I [actinobacterium SCGC AAA041-L13].	23.34	587	338	24	1	530	9	540	1e-08	68.9
rs:WP_033755449	DNA topoisomerase I [Helicobacter pylori].	23.62	470	303	13	99	537	77	521	1e-08	68.6
rs:WP_037345451	DNA topoisomerase I [Sciscionella sp. SE31].	21.75	584	353	18	2	530	23	557	1e-08	68.9
rs:WP_037452940	DNA topoisomerase I [Skermanella stibiiresistens].	21.63	615	395	20	75	630	55	641	1e-08	68.9
rs:WP_021186885	DNA topoisomerase I [Helicobacter pylori].	22.66	640	403	24	3	614	4	579	1e-08	68.6
rs:WP_029480505	DNA topoisomerase I [Deinococcus marmoris].	22.88	590	341	23	3	530	5	542	1e-08	68.9
rs:WP_041201912	DNA topoisomerase I [Helicobacter pylori].	23.32	476	297	12	99	537	77	521	1e-08	68.6
rs:WP_001942116	DNA topoisomerase [Helicobacter pylori].	22.86	468	309	12	99	537	77	521	1e-08	68.6
rs:WP_032820919	topoisomerase I, partial [Oenococcus oeni].	29.80	151	86	4	261	399	8	150	1e-08	65.5
rs:WP_021310272	DNA topoisomerase I [Helicobacter pylori].	22.22	639	407	21	3	614	4	579	1e-08	68.6
rs:WP_004481537	DNA topoisomerase I [Leptospira santarosai].	22.83	587	379	18	76	630	52	596	1e-08	68.6
rs:WP_016757400	MULTISPECIES: DNA topoisomerase I [Leptospira].	24.10	585	368	19	79	630	56	597	1e-08	68.6
rs:XP_011247268	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Mus musculus].	20.54	482	318	13	188	634	180	631	1e-08	68.9
rs:XP_012450480	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Gossypium raimondii].	23.60	517	318	19	64	536	369	852	1e-08	68.9
rs:WP_018768948	DNA topoisomerase I [Arthrobacter sp. 162MFSha1.1].	21.84	586	362	21	2	538	10	548	1e-08	68.9
rs:WP_000054708	DNA topoisomerase I [Leptospira interrogans].	23.56	675	387	25	3	630	4	596	1e-08	68.6
rs:WP_007440585	DNA topoisomerase, partial [Candidatus Arthromitus sp. SFB-2].	25.45	334	204	8	266	580	4	311	1e-08	68.2
rs:WP_000681490	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	1e-08	68.6
rs:WP_013302117	DNA topoisomerase I [Mycoplasma hyorhinis].	22.49	667	400	27	2	629	8	596	1e-08	68.6
rs:WP_001939986	DNA topoisomerase [Helicobacter pylori].	23.22	478	295	13	99	537	77	521	1e-08	68.6
rs:WP_004462295	DNA topoisomerase I [Leptospira santarosai].	23.50	583	380	19	76	630	52	596	1e-08	68.6
rs:WP_030599765	DNA topoisomerase I [Streptomyces fulvoviolaceus].	22.61	597	332	23	2	530	13	547	1e-08	68.9
tr:A0A0D4TPT2_YEASX	SubName: Full=Top3p {ECO:0000313|EMBL:AJV50325.1};	22.24	670	381	28	3	576	4	629	1e-08	68.6
rs:WP_030353279	DNA topoisomerase I [Streptomyces scopuliridis].	22.18	595	337	20	2	530	13	547	1e-08	68.9
tr:A2C7C2_PROM3	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.88	459	282	14	157	572	162	591	1e-08	68.9
rs:WP_025914261	DNA topoisomerase I [Prochlorococcus sp. scB245a_520K10].	23.53	425	260	14	188	572	175	574	1e-08	68.9
rs:WP_019063891	DNA topoisomerase I [Streptomyces prunicolor].	22.58	598	331	21	2	530	13	547	1e-08	68.9
rs:WP_001943557	DNA topoisomerase [Helicobacter pylori].	22.27	467	312	12	99	537	77	520	1e-08	68.6
rs:XP_010227764	PREDICTED: DNA topoisomerase 3-alpha-like [Brachypodium distachyon].	22.25	427	263	14	154	536	8	409	1e-08	68.6
rs:WP_000681495	DNA topoisomerase I [Helicobacter pylori].	22.10	647	398	22	3	614	4	579	1e-08	68.6
sp:TOP1_HELPY	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	22.43	642	402	23	3	614	4	579	1e-08	68.6
rs:WP_002870465	DNA topoisomerase I [Campylobacter jejuni].	22.24	652	399	23	3	618	5	584	1e-08	68.6
sp:TOP1_CAMJE	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	22.09	652	400	23	3	618	5	584	1e-08	68.6
rs:XP_006601080	PREDICTED: DNA topoisomerase 3-alpha-like isoform X6 [Glycine max].	23.33	510	317	19	64	527	304	785	1e-08	68.6
rs:WP_041488844	DNA topoisomerase I, partial [Bacillus mycoides].	35.04	137	85	3	103	236	1	136	1e-08	64.7
rs:WP_004484542	DNA topoisomerase I [Leptospira santarosai].	22.83	587	379	18	76	630	52	596	1e-08	68.6
rs:WP_030087088	DNA topoisomerase I [Streptomyces baarnensis].	21.74	598	338	20	2	530	13	549	1e-08	68.9
tr:E6NQE2_HELPQ	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	23.32	476	297	12	99	537	80	524	1e-08	68.6
tr:A0A0B8TY06_LACCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	22.56	461	293	19	200	629	2	429	1e-08	68.2
rs:WP_021601090	DNA topoisomerase I [Actinobaculum sp. oral taxon 183].	21.76	579	357	17	2	530	3	535	1e-08	68.9
rs:WP_046647868	DNA topoisomerase I [Corynebacterium minutissimum].	23.09	589	356	23	39	571	31	578	1e-08	68.9
rs:WP_018814389	DNA topoisomerase I [Salinispora pacifica].	22.17	636	375	25	2	571	9	590	1e-08	68.9
tr:M3NPB4_HELPX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.05	642	398	24	3	614	4	579	1e-08	68.6
rs:WP_013865799	DNA topoisomerase I [Microlunatus phosphovorus].	23.45	631	359	25	2	564	8	582	1e-08	68.9
rs:WP_001934270	DNA topoisomerase I [Helicobacter pylori].	22.79	645	396	25	3	614	4	579	1e-08	68.6
rs:WP_021300924	DNA topoisomerase I [Helicobacter pylori].	23.63	546	349	18	80	583	52	571	1e-08	68.6
tr:B0QZI1_MOUSE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.78	462	306	12	188	619	214	645	1e-08	68.6
tr:M6VWD0_9LEPT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.83	587	379	18	76	630	52	596	1e-08	68.6
rs:WP_046574015	DNA topoisomerase I [Spirosoma radiotolerans].	26.38	326	215	8	77	392	54	364	1e-08	68.6
rs:WP_001871307	DNA topoisomerase I [Helicobacter pylori].	23.29	468	307	11	99	537	77	521	1e-08	68.6
rs:WP_000681448	DNA topoisomerase I [Helicobacter pylori].	23.17	643	396	26	3	614	4	579	1e-08	68.6
rs:WP_005092137	MULTISPECIES: DNA topoisomerase I [Mycobacterium].	24.83	596	328	26	2	530	3	545	1e-08	68.6
rs:WP_040516161	DNA topoisomerase I [Gordonia amarae].	23.61	593	333	25	2	530	17	553	1e-08	68.9
rs:WP_025931465	MULTISPECIES: DNA topoisomerase I [Prochlorococcus].	25.23	329	205	10	261	572	270	574	1e-08	68.6
rs:WP_002913205	DNA topoisomerase I [Campylobacter jejuni].	22.55	652	397	24	3	618	5	584	1e-08	68.6
rs:WP_019476900	DNA topoisomerase I [Prochlorococcus sp. W7].	24.64	422	259	14	188	572	175	574	1e-08	68.6
rs:WP_033745297	DNA topoisomerase I [Helicobacter pylori].	23.03	469	306	14	99	537	77	520	1e-08	68.6
rs:WP_006604135	DNA topoisomerase I [Streptomyces auratus].	23.06	607	329	22	2	530	14	560	1e-08	68.6
rs:WP_040966555	DNA topoisomerase I [Campylobacter jejuni].	22.09	652	400	23	3	618	5	584	1e-08	68.6
tr:W6V0X6_ECHGR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.39	389	252	14	35	394	64	435	1e-08	68.9
rs:WP_010888015	DNA topoisomerase I [Deinococcus radiodurans].	23.19	595	337	23	3	530	48	589	1e-08	68.9
rs:WP_001926900	DNA topoisomerase I [Helicobacter pylori].	23.17	643	396	26	3	614	4	579	1e-08	68.6
rs:WP_000681481	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	1e-08	68.6
rs:WP_016756882	DNA topoisomerase I [Leptospira santarosai].	23.50	583	380	19	76	630	52	596	1e-08	68.2
rs:WP_009612532	DNA topoisomerase I [actinobacterium SCGC AAA027-L06].	22.77	584	342	22	2	530	4	533	1e-08	68.6
rs:WP_042390214	DNA topoisomerase I [Streptacidiphilus melanogenes].	22.37	599	340	24	2	530	13	556	1e-08	68.6
tr:W1HS00_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	24.59	362	240	9	60	409	78	418	1e-08	68.2
rs:WP_001927948	DNA topoisomerase [Helicobacter pylori].	29.74	232	144	7	103	317	73	302	1e-08	68.6
tr:Q9JJ62_MOUSE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.39	436	281	17	3	399	5	426	1e-08	67.8
rs:WP_020712052	hypothetical protein [Acidobacteriaceae bacterium KBS 89].	21.02	704	419	23	3	625	5	652	1e-08	68.6
rs:WP_044278477	DNA topoisomerase I [Campylobacter jejuni].	22.09	652	400	23	3	618	5	584	1e-08	68.6
rs:WP_000054709	DNA topoisomerase I [Leptospira interrogans].	23.56	675	387	25	3	630	4	596	1e-08	68.2
rs:WP_039411736	DNA topoisomerase I [Microbacterium hominis].	22.82	504	292	19	90	538	87	548	1e-08	68.6
rs:WP_001938164	DNA topoisomerase I [Helicobacter pylori].	22.50	640	404	24	3	614	4	579	1e-08	68.6
rs:WP_043012938	DNA topoisomerase 1 [Campylobacter jejuni].	22.09	652	400	23	3	618	5	584	1e-08	68.6
rs:WP_005086898	DNA topoisomerase I [Mycobacterium abscessus].	24.83	596	328	26	2	530	3	545	1e-08	68.6
rs:WP_005083492	DNA topoisomerase I [Mycobacterium abscessus].	24.83	596	328	26	2	530	3	545	1e-08	68.6
rs:WP_046084579	DNA topoisomerase I [Streptomyces yogyakartensis].	22.15	596	337	22	2	530	14	549	1e-08	68.6
tr:T1A8I7_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EQD53322.1}; Flags: Fragment;	23.45	354	237	15	27	365	41	375	1e-08	67.4
rs:WP_001890680	DNA topoisomerase I [Helicobacter pylori].	23.11	476	298	12	99	537	77	521	1e-08	68.6
rs:WP_021172579	DNA topoisomerase I [Helicobacter pylori].	29.41	255	159	8	80	317	52	302	1e-08	68.6
tr:J0S3Z3_HELPX	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EJC30263.1};	29.74	232	144	7	103	317	73	302	2e-08	67.8
rs:WP_001948369	DNA topoisomerase I [Helicobacter pylori].	23.05	642	398	24	3	614	4	579	2e-08	68.6
rs:WP_018217137	DNA topoisomerase I [Salinispora pacifica].	22.26	638	372	26	2	571	9	590	2e-08	68.6
rs:WP_014273075	DNA topoisomerase I [Mycoplasma haemocanis].	22.74	598	372	22	83	630	66	623	2e-08	68.6
rs:WP_024862330	DNA topoisomerase I [Pediococcus acidilactici].	21.44	569	384	18	90	629	70	604	2e-08	68.6
tr:J6ZEN4_ENTFC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.52	572	349	26	103	635	99	632	2e-08	68.6
tr:N4T6S5_HELPX	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:ENH58898.1};	32.00	175	105	5	157	317	128	302	2e-08	68.2
tr:A0A099SXT5_METMT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.07	579	394	17	86	629	87	637	2e-08	68.6
rs:WP_016644692	DNA topoisomerase 1 [Streptomyces aurantiacus].	22.43	593	338	20	2	530	13	547	2e-08	68.6
rs:WP_036883715	DNA topoisomerase I [Porphyromonas gingivicanis].	23.34	604	362	25	3	578	7	537	2e-08	68.6
rs:XP_011817027	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Colobus angolensis palliatus].	22.44	468	291	14	188	619	144	575	2e-08	68.6
rs:WP_038819896	hypothetical protein, partial [Pseudomonas savastanoi].	22.12	642	402	21	2	616	3	573	2e-08	68.2
rs:WP_045812520	DNA topoisomerase I [Rickettsia hoogstraalii].	21.92	698	405	29	1	629	1	627	2e-08	68.6
tr:A0A094BYZ8_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY46894.1};	21.72	557	358	21	3	520	6	523	2e-08	68.6
rs:WP_001955993	DNA topoisomerase [Helicobacter pylori].	23.66	465	295	15	157	583	128	570	2e-08	68.6
tr:A0A0D4V1D3_YEASX	SubName: Full=Top3p {ECO:0000313|EMBL:AJV65981.1};	22.24	670	381	28	3	576	4	629	2e-08	68.2
rs:WP_033756196	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	24	3	614	4	579	2e-08	68.6
rs:WP_024116767	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	2e-08	68.6
rs:WP_016893440	DNA topoisomerase I [Mycobacterium abscessus].	24.83	596	328	26	2	530	3	545	2e-08	68.6
rs:WP_014392084	DNA topoisomerase I [Candidatus Rickettsia amblyommii].	22.40	683	420	29	1	629	1	627	2e-08	68.6
rs:WP_000681461	DNA topoisomerase I [Helicobacter pylori].	22.15	650	394	23	3	614	4	579	2e-08	68.6
rs:WP_021177330	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	2e-08	68.6
rs:WP_040022574	DNA topoisomerase I [Streptomyces sp. 150FB].	22.32	596	335	21	2	530	13	547	2e-08	68.6
tr:A0A0E0LAF6_ORYPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OPUNC06G10370.1};	27.69	260	153	9	100	334	380	629	2e-08	68.6
rs:WP_001931094	DNA topoisomerase I [Helicobacter pylori].	22.71	643	399	25	3	614	4	579	2e-08	68.6
rs:WP_018089992	DNA topoisomerase I [Streptomyces sp. FxanaC1].	22.85	617	323	23	2	530	14	565	2e-08	68.6
rs:WP_044778602	DNA topoisomerase I [Campylobacter jejuni].	22.24	652	399	23	3	618	5	584	2e-08	68.2
rs:XP_006601076	PREDICTED: DNA topoisomerase 3-alpha-like isoform X2 [Glycine max].	23.33	510	317	19	64	527	304	785	2e-08	68.6
tr:Q8CDI8_MOUSE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	20.75	482	317	14	188	634	124	575	2e-08	68.6
rs:WP_018226243	DNA topoisomerase I [actinobacterium SCGC AAA028-A23].	22.77	584	342	22	2	530	4	533	2e-08	68.6
sp:TOP1_RICPR	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	22.55	683	419	28	1	629	1	627	2e-08	68.6
rs:WP_000681511	DNA topoisomerase I [Helicobacter pylori].	22.66	640	403	24	3	614	4	579	2e-08	68.6
rs:WP_033995540	DNA topoisomerase I [Pseudomonas aeruginosa].	22.13	506	299	18	74	537	59	511	2e-08	68.2
rs:WP_002874307	DNA topoisomerase I [Campylobacter jejuni].	22.09	652	400	23	3	618	5	584	2e-08	68.2
rs:WP_026100121	DNA topoisomerase I [Microchaete sp. PCC 7126].	21.04	618	374	18	3	560	4	567	2e-08	68.6
rs:WP_045800259	DNA topoisomerase I [Candidatus Rickettsia amblyommii].	22.40	683	420	29	1	629	1	627	2e-08	68.6
rs:WP_039665002	DNA topoisomerase I [Campylobacter volucris].	21.47	652	404	22	3	618	4	583	2e-08	68.2
tr:U7PYT6_SPOS1	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ERT00768.1};	21.43	560	375	18	3	526	5	535	2e-08	68.2
rs:WP_044119047	DNA topoisomerase III, partial [Staphylococcus aureus].	28.40	169	111	4	458	620	4	168	2e-08	65.5
rs:WP_023971651	hypothetical protein, partial [Salmonella enterica].	38.64	88	54	0	494	581	1	88	2e-08	64.3
rs:WP_025309579	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	2e-08	68.2
rs:WP_010620889	topoisomerase IA, partial [Lactobacillus malefermentans].	32.52	123	77	3	3	121	4	124	2e-08	64.3
tr:A0A0D4UPY3_YEASX	SubName: Full=Top3p {ECO:0000313|EMBL:AJV62006.1};	22.24	670	381	28	3	576	4	629	2e-08	68.2
rs:WP_016891982	DNA topoisomerase I [Mycobacterium abscessus].	24.83	596	328	26	2	530	3	545	2e-08	68.6
rs:WP_013247607	DNA topoisomerase I [Candidatus Nitrospira defluvii].	21.99	614	372	20	3	561	5	566	2e-08	68.6
rs:WP_024751547	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	2e-08	68.2
sp:RGYR_PYRFU	RecName: Full=Reverse gyrase {ECO:0000255|HAMAP-Rule:MF_01125}; Includes: RecName: Full=Helicase {ECO:0000255|HAMAP-Rule:MF_01125}; EC=3.6.4.12 {ECO:0000255|HAMAP-Rule:MF_01125}; Includes: RecName: Full=Topoisomerase {ECO:0000255|HAMAP-Rule:MF_01125}; EC=5.99.1.3 {ECO:0000255|HAMAP-Rule:MF_01125};	22.54	448	263	13	162	584	826	1214	2e-08	68.6
rs:NP_711902	DNA topoisomerase [Leptospira interrogans serovar Lai str. 56601].	23.56	675	387	25	3	630	4	596	2e-08	68.2
rs:WP_023025047	MULTISPECIES: DNA topoisomerase I [Corynebacterium].	23.80	563	312	22	38	530	30	545	2e-08	68.6
rs:WP_044145816	DNA topoisomerase I, partial [Enterococcus faecium].	25.52	572	349	26	103	635	81	614	2e-08	68.2
rs:WP_000681483	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	2e-08	68.2
tr:A0A0C3FUZ3_9HOMO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.82	634	396	20	3	577	4	590	2e-08	68.2
tr:A0A0D2MGB4_9CHLO	SubName: Full=Strain SAG 48.87 unplaced genomic scaffold scaffold01530, whole genome shotgun sequence {ECO:0000313|EMBL:KIY99766.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIY99766.1}; Flags: Fragment;	22.14	411	241	14	264	625	43	423	2e-08	68.2
rs:WP_024059594	hypothetical protein [Varibaculum cambriense].	23.02	582	348	21	2	530	5	539	2e-08	68.6
rs:WP_045039901	DNA topoisomerase III [Photobacterium iliopiscarium].	31.82	110	65	4	3	108	4	107	2e-08	64.3
tr:A0A0D4V7D1_YEASX	SubName: Full=Top3p {ECO:0000313|EMBL:AJV68674.1};	22.21	671	380	28	3	576	4	629	2e-08	68.2
rs:WP_027480031	DNA topoisomerase I [Deinococcus radiodurans].	23.19	595	337	23	3	530	10	551	2e-08	68.6
rs:WP_030507893	DNA topoisomerase I [Microbispora rosea].	22.66	684	360	29	2	591	12	620	2e-08	68.6
rs:WP_000681421	DNA topoisomerase I [Helicobacter pylori].	22.50	640	404	24	3	614	4	579	2e-08	68.2
rs:WP_030718342	DNA topoisomerase I [Streptomyces griseus].	21.28	592	348	19	2	530	13	549	2e-08	68.6
tr:A0A0D4TSX7_YEASX	SubName: Full=Top3p {ECO:0000313|EMBL:AJV50776.1};	22.24	670	381	28	3	576	4	629	2e-08	68.2
rs:WP_005102351	DNA topoisomerase I [Mycobacterium abscessus].	24.83	596	328	26	2	530	3	545	2e-08	68.6
rs:WP_033768970	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	2e-08	68.2
rs:WP_000681454	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	2e-08	68.2
rs:XP_007213059	hypothetical protein PRUPE_ppa020488mg, partial [Prunus persica].	22.94	449	289	18	79	489	90	519	2e-08	67.8
rs:WP_014666685	DNA topoisomerase I [Helicobacter cinaedi].	24.74	570	317	22	3	528	4	505	2e-08	68.2
gp:CP003231_259	DNA topoisomerase I [Mycoplasma hyorhinis GDL-1]	22.04	667	403	26	2	629	3	591	2e-08	68.2
rs:WP_037228878	DNA topoisomerase I [Rhodococcus wratislaviensis].	22.80	592	338	21	2	530	21	556	2e-08	68.6
rs:WP_010189916	DNA topoisomerase I [Corynebacterium aurimucosum].	23.34	587	357	23	39	571	31	578	2e-08	68.6
rs:WP_000681484	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	2e-08	68.2
rs:WP_017199192	DNA topoisomerase I [Arthrobacter sp. M2012083].	21.58	584	366	21	2	538	10	548	2e-08	68.6
rs:WP_004479531	DNA topoisomerase I [Leptospira santarosai].	22.83	587	379	18	76	630	52	596	2e-08	68.2
rs:WP_037203507	MULTISPECIES: DNA topoisomerase I [Rhodococcus].	22.80	592	338	21	2	530	21	556	2e-08	68.6
rs:WP_046916528	DNA topoisomerase I [Streptomyces stelliscabiei].	23.04	599	327	25	2	530	13	547	2e-08	68.6
tr:M2UQN7_COCH5	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.42	565	363	22	3	525	5	530	2e-08	68.2
rs:WP_007298531	DNA topoisomerase I [Rhodococcus imtechensis].	22.80	592	338	21	2	530	21	556	2e-08	68.6
rs:WP_025287779	DNA topoisomerase I [Helicobacter pylori].	22.50	640	404	24	3	614	4	579	2e-08	68.2
rs:WP_033776699	DNA topoisomerase I [Helicobacter pylori].	22.27	642	403	23	3	614	4	579	2e-08	68.2
rs:WP_044374707	DNA topoisomerase I [Streptomyces griseus].	21.45	592	347	19	2	530	13	549	2e-08	68.6
rs:WP_030813093	DNA topoisomerase I [Streptomyces mediolani].	21.45	592	347	19	2	530	13	549	2e-08	68.6
rs:WP_009399149	DNA topoisomerase I [Pseudomonas putida].	22.62	557	373	15	84	614	69	593	2e-08	68.2
rs:WP_010724785	hypothetical protein, partial [Enterococcus faecium].	32.22	180	102	7	154	317	13	188	2e-08	65.1
rs:WP_000681463	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	2e-08	68.2
tr:J9EGV0_WUCBA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.00	225	138	8	188	399	49	262	2e-08	65.9
rs:WP_038893010	DNA topoisomerase III, partial [Vibrio campbellii].	26.01	223	148	6	349	555	17	238	2e-08	65.5
rs:WP_004804488	hypothetical protein, partial [Eggerthia catenaformis].	34.87	152	81	4	420	564	38	178	2e-08	65.1
rs:WP_040499342	DNA topoisomerase I, partial [Helicobacter suis].	22.38	496	317	16	76	529	47	516	2e-08	68.2
rs:WP_038398842	DNA topoisomerase I [Enterococcus faecium].	25.52	572	349	26	103	635	81	614	2e-08	68.2
rs:WP_034268541	DNA topoisomerase I [Amycolatopsis halophila].	23.99	596	330	23	2	530	20	559	2e-08	68.2
rs:XP_009064575	hypothetical protein LOTGIDRAFT_236127 [Lottia gigantea].	22.77	470	286	19	188	619	217	647	2e-08	68.2
rs:WP_014582537	DNA topoisomerase I [Mycoplasma hyorhinis].	22.04	667	403	26	2	629	8	596	2e-08	68.2
rs:WP_007540097	DNA topoisomerase I [Candidatus Aquiluna sp. IMCC13023].	23.44	576	339	18	2	528	4	526	2e-08	68.2
tr:A0A074WEW7_9PEZI	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:KEQ61046.1};	22.40	567	353	22	3	520	6	534	2e-08	68.2
rs:WP_044882774	DNA topoisomerase I [Neochlamydia sp. EPS4].	21.98	605	374	22	82	630	59	621	2e-08	68.2
rs:WP_018252543	DNA topoisomerase I [Salinispora pacifica].	22.01	636	376	25	2	571	9	590	2e-08	68.2
rs:WP_005065496	DNA topoisomerase I [Mycobacterium abscessus].	24.83	596	328	26	2	530	3	545	2e-08	68.2
rs:WP_004996071	DNA topoisomerase I [Rickettsia sibirica].	21.81	697	407	28	1	629	1	627	2e-08	68.2
rs:WP_033952290	DNA topoisomerase I [Streptomyces sp. CNQ431].	22.45	588	343	20	2	530	13	546	2e-08	68.2
rs:WP_000681411	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	2e-08	68.2
rs:WP_024369719	DNA topoisomerase I [Helicobacter pylori].	29.74	232	144	7	103	317	73	302	2e-08	68.2
rs:WP_014411681	DNA topoisomerase 1 [Rickettsia prowazekii].	22.55	683	419	28	1	629	1	627	2e-08	68.2
rs:WP_038538797	DNA topoisomerase I [endosymbiont of Acanthamoeba sp. UWC8].	23.25	684	415	23	1	630	1	628	2e-08	68.2
rs:WP_005171670	DNA topoisomerase I [Gordonia aichiensis].	23.99	592	336	24	2	530	17	557	2e-08	68.6
rs:WP_021308843	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	2e-08	68.2
tr:G4AHU9_AGGAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.69	357	225	9	298	633	3	329	2e-08	67.8
rs:WP_017208335	DNA topoisomerase I [Mycobacterium abscessus].	24.83	596	328	26	2	530	3	545	2e-08	68.2
rs:WP_014271302	DNA topoisomerase I [Sphaerochaeta pleomorpha].	22.00	491	325	10	77	533	56	522	2e-08	68.2
rs:WP_000655380	DNA topoisomerase I [Helicobacter pylori].	29.41	255	159	8	80	317	52	302	2e-08	68.2
rs:XP_011830675	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Mandrillus leucophaeus].	22.44	468	291	14	188	619	144	575	2e-08	68.2
rs:WP_002884212	DNA topoisomerase I [Campylobacter jejuni].	22.85	652	395	25	3	618	5	584	2e-08	68.2
rs:WP_002274188	DNA topoisomerase I, partial [Streptococcus mutans].	25.75	268	179	9	87	344	82	339	2e-08	67.0
rs:WP_000681402	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	2e-08	68.2
rs:WP_002956759	DNA topoisomerase I [Helicobacter cinaedi].	24.74	570	317	22	3	528	4	505	2e-08	68.2
rs:WP_045916818	DNA topoisomerase I [Orientia tsutsugamushi].	23.40	577	333	20	1	534	1	511	2e-08	68.2
rs:XP_012450479	PREDICTED: uncharacterized protein LOC105773277 isoform X1 [Gossypium raimondii].	23.60	517	318	19	64	536	369	852	2e-08	68.6
rs:WP_033736007	DNA topoisomerase I [Helicobacter pylori].	22.15	650	394	23	3	614	4	579	2e-08	68.2
tr:G1V000_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.85	156	102	4	289	441	1	150	2e-08	65.1
rs:WP_046910172	DNA topoisomerase I [Streptomyces showdoensis].	22.07	589	345	21	2	530	13	547	2e-08	68.2
rs:WP_046833762	hypothetical protein [Xanthomonas axonopodis].	32.81	128	76	3	276	393	3	130	2e-08	65.1
rs:WP_027654764	DNA topoisomerase I [Salinispora pacifica].	22.01	636	376	25	2	571	9	590	2e-08	68.2
tr:C7GH18_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.85	135	87	1	200	334	1	130	2e-08	64.3
rs:WP_016341720	DNA topoisomerase I subunit omega [Mycobacterium abscessus].	24.71	595	330	26	2	530	3	545	2e-08	68.2
rs:WP_012926623	DNA topoisomerase I [Spirosoma linguale].	26.69	326	214	8	77	392	54	364	2e-08	68.2
tr:A0A090Q0M1_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.28	534	323	19	3	521	5	477	2e-08	68.2
rs:WP_015427359	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	2e-08	68.2
rs:WP_016762302	DNA topoisomerase I [Leptospira kirschneri].	23.33	673	391	24	3	630	4	596	2e-08	67.8
rs:XP_009033283	hypothetical protein AURANDRAFT_19616, partial [Aureococcus anophagefferens].	23.37	582	390	21	3	554	5	560	2e-08	68.2
rs:WP_018531980	DNA topoisomerase I [Streptomyces sp. HmicA12].	22.26	602	331	23	2	530	13	550	2e-08	68.2
rs:WP_007237854	DNA topoisomerase I [Gordonia otitidis].	23.57	594	336	24	2	530	17	557	2e-08	68.2
rs:WP_004493282	DNA topoisomerase I [Leptospira santarosai].	22.83	587	379	18	76	630	52	596	2e-08	67.8
rs:WP_017534610	DNA topoisomerase I [Nocardiopsis alba].	21.79	592	343	21	3	530	25	560	2e-08	68.2
rs:WP_021172441	DNA topoisomerase I [Helicobacter pylori].	22.66	640	403	24	3	614	4	579	2e-08	68.2
rs:WP_046581580	DNA topoisomerase I [Streptomyces sp. MUSC149T].	22.67	600	328	23	2	530	13	547	2e-08	68.2
rs:WP_016926149	DNA topoisomerase I [Rickettsia conorii].	21.95	697	406	28	1	629	1	627	2e-08	68.2
rs:WP_014273369	DNA topoisomerase I [Rickettsia slovaca].	21.95	697	406	28	1	629	1	627	2e-08	68.2
tr:A0A0D4TS41_YEASX	SubName: Full=Top3p {ECO:0000313|EMBL:AJV51222.1};	23.95	430	257	17	188	576	229	629	2e-08	67.8
rs:XP_009622051	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Nicotiana tomentosiformis].	22.51	622	355	25	3	585	14	547	2e-08	68.2
rs:WP_024060732	DNA topoisomerase, partial [Veillonella dispar].	30.00	150	103	1	449	596	73	222	2e-08	65.1
rs:WP_012816676	DNA topoisomerase III, partial [Staphylococcus aureus].	28.57	168	110	4	459	620	1	164	2e-08	65.1
rs:XP_012764839	DNA topoisomerase III, putative [Plasmodium reichenowi].	26.67	330	185	13	251	557	363	658	2e-08	67.8
rs:WP_042689032	reverse gyrase [Thermococcus nautili].	23.65	389	230	13	162	533	830	1168	2e-08	68.2
rs:WP_042242210	DNA topoisomerase I [Neochlamydia sp. S13].	21.98	605	374	22	82	630	59	621	2e-08	68.2
rs:WP_036496366	DNA topoisomerase I, partial [Nocardia sp. BMG111209].	22.28	597	339	22	2	530	20	559	2e-08	68.2
rs:XP_012738680	hypothetical protein GMDG_00290 [Pseudogymnoascus destructans 20631-21].	21.40	556	361	21	3	520	6	523	2e-08	67.8
rs:WP_042282227	DNA topoisomerase I [Nocardiopsis sp. TP-A0876].	21.79	592	343	21	3	530	25	560	2e-08	68.2
rs:WP_003013852	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	2e-08	68.2
rs:WP_001941587	DNA topoisomerase I [Helicobacter pylori].	22.72	647	394	24	3	614	4	579	2e-08	67.8
rs:WP_036725514	DNA topoisomerase III, partial [Paenibacillus forsythiae].	26.85	149	87	3	467	615	1	127	2e-08	65.1
rs:WP_036848414	DNA topoisomerase I [Porphyromonas cangingivalis].	21.93	538	340	18	3	523	5	479	2e-08	68.2
rs:WP_005208330	DNA topoisomerase I [Gordonia sputi].	23.69	591	339	23	2	530	17	557	2e-08	68.2
rs:WP_032814236	DNA topoisomerase I [Gardnerella vaginalis].	22.71	621	385	22	2	571	6	582	2e-08	68.2
tr:A0A074TPN5_9MICO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KEP73622.1}; Flags: Fragment;	32.18	87	53	3	31	113	12	96	2e-08	64.3
rs:WP_001974755	DNA topoisomerase I [Helicobacter pylori].	22.79	645	396	25	3	614	4	579	2e-08	67.8
rs:WP_000681480	DNA topoisomerase I [Helicobacter pylori].	22.07	639	408	22	3	614	4	579	2e-08	67.8
rs:WP_025933212	DNA topoisomerase I [Prochlorococcus sp. scB243_498A3].	25.23	329	205	10	261	572	270	574	2e-08	68.2
rs:WP_031887220	DNA topoisomerase III, partial [Staphylococcus aureus].	28.40	169	111	4	458	620	25	189	2e-08	65.5
rs:WP_000655374	DNA topoisomerase I [Helicobacter pylori].	22.77	527	342	15	103	588	73	575	2e-08	67.8
tr:A0A0C1HCF0_9CHLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.98	605	374	22	82	630	72	634	2e-08	68.2
rs:WP_013283654	MULTISPECIES: DNA topoisomerase I [Micromonospora].	21.86	636	377	24	2	571	9	590	2e-08	68.2
rs:WP_009067753	MULTISPECIES: DNA topoisomerase I [Streptomyces].	22.52	595	334	24	2	530	13	546	2e-08	68.2
rs:WP_007823869	DNA topoisomerase I [Streptomyces sp. Tu6071].	22.52	595	334	24	2	530	13	546	2e-08	68.2
rs:WP_009716793	DNA topoisomerase I [Streptomyces himastatinicus].	22.03	590	345	21	2	530	14	549	2e-08	68.2
rs:WP_029020712	DNA topoisomerase I [Salinispora arenicola].	22.80	636	371	28	2	571	9	590	2e-08	68.2
rs:XP_007290021	DNA topoisomerase [Marssonina brunnea f. sp. 'multigermtubi' MB_m1].	23.77	345	222	12	188	520	218	533	2e-08	67.8
rs:WP_000681471	DNA topoisomerase I [Helicobacter pylori].	22.41	638	407	20	3	614	4	579	2e-08	67.8
rs:WP_016755266	DNA topoisomerase I [Leptospira santarosai].	23.33	583	381	18	76	630	52	596	2e-08	67.8
rs:WP_039383557	DNA topoisomerase I [Neochlamydia sp. TUME1].	22.22	603	375	22	82	630	59	621	2e-08	68.2
rs:WP_004766649	DNA topoisomerase I [Leptospira kirschneri].	23.33	673	391	24	3	630	4	596	2e-08	67.8
rs:WP_029362891	DNA topoisomerase I [Helicobacter pylori].	23.17	643	396	26	3	614	4	579	2e-08	67.8
rs:WP_021303226	DNA topoisomerase I [Helicobacter pylori].	22.27	642	403	23	3	614	4	579	2e-08	67.8
rs:WP_046565845	DNA topoisomerase I [Micromonospora sp. HK10].	22.29	637	373	26	2	571	9	590	2e-08	68.2
rs:WP_041375056	DNA topoisomerase I [Prochlorococcus marinus].	22.88	459	282	14	157	572	145	574	2e-08	68.2
rs:WP_042980269	DNA topoisomerase III, partial [Vibrio owensii].	25.17	294	190	11	1	274	1	284	2e-08	65.9
rs:WP_035192062	DNA topoisomerase I, partial [Acidithiobacillus ferrivorans].	23.43	397	257	17	85	445	62	447	2e-08	67.4
rs:WP_013562745	DNA topoisomerase [Desulfurococcus mucosus].	20.91	526	340	15	78	578	722	1196	2e-08	68.2
rs:WP_015086308	topoisomerase I [Helicobacter pylori].	23.08	468	308	11	99	537	77	521	2e-08	67.8
rs:WP_030897702	DNA topoisomerase I [Streptomyces sp. NRRL S-474].	22.78	597	331	22	2	530	13	547	2e-08	68.2
rs:WP_006275828	DNA topoisomerase I [Cylindrospermopsis raciborskii].	22.09	507	334	13	90	560	80	561	2e-08	67.8
rs:WP_030591020	DNA topoisomerase I [Streptomyces globisporus].	21.28	592	348	19	2	530	13	549	2e-08	68.2
rs:WP_024365688	DNA topoisomerase I [Arthrobacter sp. TB 26].	22.50	591	356	21	2	538	10	552	2e-08	67.8
tr:A0A0D4UHK0_YEASX	SubName: Full=Top3p {ECO:0000313|EMBL:AJV60198.1};	22.24	670	381	28	3	576	4	629	2e-08	67.8
rs:WP_025222407	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	2e-08	67.8
rs:WP_000681496	DNA topoisomerase I [Helicobacter pylori].	22.66	640	403	24	3	614	4	579	2e-08	67.8
rs:WP_000681469	DNA topoisomerase I [Helicobacter pylori].	22.71	643	399	25	3	614	4	579	2e-08	67.8
rs:WP_030561185	DNA topoisomerase I [Streptomyces aureocirculatus].	22.52	595	335	23	2	530	13	547	2e-08	68.2
rs:WP_026734142	DNA topoisomerase I [Fischerella sp. PCC 9605].	21.21	429	277	9	187	574	173	581	2e-08	67.8
rs:WP_032591081	DNA topoisomerase I [Campylobacter jejuni].	22.24	652	399	23	3	618	5	584	2e-08	67.8
rs:XP_012682632	PREDICTED: DNA topoisomerase 3-alpha [Clupea harengus].	22.20	527	323	17	188	667	242	728	2e-08	68.2
rs:WP_031080986	DNA topoisomerase I [Streptomyces sp. NRRL WC-3549].	21.96	592	344	20	2	530	13	549	2e-08	67.8
rs:WP_022853495	topoisomerase [Thermodesulfatator atlanticus].	24.67	535	308	24	72	576	671	1140	2e-08	68.2
rs:WP_033595889	DNA topoisomerase I [Helicobacter pylori].	23.83	470	301	14	99	537	77	520	2e-08	67.8
rs:WP_015643269	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	2e-08	67.8
tr:A0A076GWJ3_ENTFC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.52	572	349	26	103	635	99	632	3e-08	67.8
tr:A0A086FA68_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.92	418	228	12	3	392	5	360	3e-08	67.8
tr:S7VN75_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.51	244	157	6	154	392	58	291	3e-08	66.2
rs:WP_021999052	DNA topoisomerase [Acetobacter sp. CAG:977].	21.50	679	432	27	1	629	1	628	3e-08	67.8
rs:WP_041222931	DNA topoisomerase I, partial [Deinococcus proteolyticus].	21.71	585	347	19	3	530	5	535	3e-08	67.8
tr:F0RMD4_DEIPM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.71	585	347	19	3	530	5	535	3e-08	67.8
rs:WP_025955280	DNA topoisomerase I [Prochlorococcus sp. scB243_498I20].	25.23	329	205	10	261	572	270	574	3e-08	67.8
rs:WP_032825422	topoisomerase I, partial [Oenococcus oeni].	29.14	151	87	4	261	399	16	158	3e-08	64.3
tr:U7UTY2_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.32	591	383	17	82	629	65	616	3e-08	67.8
rs:WP_030046534	DNA topoisomerase I [Streptomyces peruviensis].	22.37	590	342	21	2	530	13	547	3e-08	67.8
tr:I9WJG6_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	22.98	470	306	14	99	537	702	1146	3e-08	68.2
rs:WP_000681486	DNA topoisomerase I [Helicobacter pylori].	22.81	640	402	25	3	614	4	579	3e-08	67.8
tr:H9JC36_BOMMO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.83	328	184	13	252	560	215	505	3e-08	67.8
tr:N4TAY4_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	22.65	468	310	12	99	537	80	524	3e-08	67.4
rs:XP_008684206	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha [Ursus maritimus].	22.61	482	298	17	193	634	211	657	3e-08	67.8
rs:WP_002376296	topoisomerase [Enterococcus faecium].	41.75	103	56	1	103	201	3	105	3e-08	63.2
tr:A0A097QUC2_9EURY	RecName: Full=Reverse gyrase {ECO:0000256|HAMAP-Rule:MF_01125, ECO:0000256|RuleBase:RU004026};	23.23	452	254	15	162	583	830	1218	3e-08	68.2
tr:A0A0D6L2I0_9CYAN	SubName: Full=DNA topoisomerase TopA {ECO:0000313|EMBL:EKF05951.1};	21.64	536	329	14	90	574	51	546	3e-08	67.8
rs:WP_033582285	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	3e-08	67.8
rs:WP_024773959	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	24	3	614	4	579	3e-08	67.8
rs:WP_009358544	DNA topoisomerase I [Arthrobacter nitrophenolicus].	21.75	584	365	21	2	538	10	548	3e-08	67.8
rs:WP_036464620	DNA topoisomerase I [Mycoplasma sturni].	21.61	634	402	23	33	629	22	597	3e-08	67.4
tr:A0A0D0XBT8_CRYGA	SubName: Full=Unplaced genomic scaffold supercont1.2, whole genome shotgun sequence {ECO:0000313|EMBL:KIR68866.1};	21.23	650	412	23	3	598	4	607	3e-08	67.8
rs:WP_030734103	DNA topoisomerase I [Streptomyces sp. NRRL S-31].	22.86	595	333	21	2	530	13	547	3e-08	67.8
tr:A0A0B0N239_GOSAR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.00	220	150	4	188	396	243	458	3e-08	67.4
rs:WP_004465158	DNA topoisomerase I [Leptospira santarosai].	23.00	587	378	18	76	630	52	596	3e-08	67.4
rs:WP_000681523	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	3e-08	67.8
tr:T2S7Z6_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	23.62	470	303	13	99	537	77	521	3e-08	67.4
rs:WP_039307621	hypothetical protein [Clostridium botulinum].	32.46	114	61	4	3	109	5	109	3e-08	63.5
rs:WP_031368472	hypothetical protein, partial [Clostridium botulinum].	40.40	99	48	5	2	94	3	96	3e-08	63.2
rs:WP_023539660	DNA topoisomerase I [Streptomyces niveus].	22.52	595	335	22	2	530	13	547	3e-08	67.8
rs:WP_032470244	DNA topoisomerase III, partial [Vibrio cholerae].	33.33	111	64	4	2	108	3	107	3e-08	63.5
rs:WP_036457573	DNA topoisomerase I [Mycobacterium sp. UM_WGJ].	23.60	589	340	21	2	530	13	551	3e-08	67.8
rs:WP_002892042	DNA topoisomerase I [Campylobacter jejuni].	22.09	652	400	23	3	618	5	584	3e-08	67.4
rs:WP_000277556	DNA topoisomerase I [Helicobacter pylori].	22.86	468	309	11	99	537	77	521	3e-08	67.4
rs:WP_007450295	DNA topoisomerase I [Streptomyces sp. W007].	21.74	598	338	20	2	530	13	549	3e-08	67.8
rs:WP_005475914	topA protein [Streptomyces bottropensis].	22.82	596	332	23	2	530	13	547	3e-08	67.8
rs:WP_000681444	DNA topoisomerase I [Helicobacter pylori].	22.87	647	393	24	3	614	4	579	3e-08	67.4
rs:XP_011144136	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Harpegnathos saltator].	21.99	482	311	19	188	634	222	673	3e-08	67.8
rs:WP_000277567	DNA topoisomerase I [Helicobacter pylori].	23.08	468	308	11	99	537	77	521	3e-08	67.4
tr:K1T5M9_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EKC64968.1}; Flags: Fragment;	24.35	345	208	13	295	616	1	315	3e-08	66.2
tr:B5HVG2_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.95	597	330	22	2	530	26	560	3e-08	67.8
rs:WP_036286299	DNA topoisomerase I [Microbacterium sp. MRS-1].	22.95	501	295	18	90	538	87	548	3e-08	67.8
rs:WP_033514412	DNA topoisomerase I [Bifidobacterium pullorum].	21.70	636	388	20	2	571	6	597	3e-08	67.8
rs:WP_025454946	DNA topoisomerase I [Helicobacter pylori].	22.65	468	310	12	99	537	77	521	3e-08	67.4
rs:WP_045867561	DNA topoisomerase I [Tolypothrix sp. PCC 7601].	21.64	536	329	14	90	574	80	575	3e-08	67.8
rs:XP_012523362	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Monomorium pharaonis].	23.32	386	253	11	188	560	207	562	3e-08	67.8
rs:WP_000681443	DNA topoisomerase I [Helicobacter pylori].	22.66	640	403	24	3	614	4	579	3e-08	67.4
rs:WP_013110457	DNA topoisomerase I [Planctomyces limnophilus].	22.63	623	354	24	3	560	9	568	3e-08	67.8
rs:WP_034574745	DNA topoisomerase I, partial [Helicobacter sanguini].	24.82	419	246	17	241	629	18	397	3e-08	67.0
rs:WP_032782336	DNA topoisomerase I [Streptomyces sp. JS01].	21.28	592	348	19	2	530	13	549	3e-08	67.8
rs:WP_037900954	DNA topoisomerase I [Streptomyces sviceus].	22.95	597	330	22	2	530	13	547	3e-08	67.8
rs:WP_016464462	DNA topoisomerase I [Microbacterium sp. oral taxon 186].	22.95	501	295	18	90	538	87	548	3e-08	67.8
rs:WP_009776219	DNA topoisomerase I [Janibacter sp. HTCC2649].	23.63	584	341	20	2	530	9	542	3e-08	67.8
rs:WP_040201666	DNA topoisomerase I, partial [Klebsiella pneumoniae].	24.31	362	241	9	60	409	78	418	3e-08	66.6
rs:WP_010056058	DNA topoisomerase I [Streptomyces globisporus].	21.28	592	348	19	2	530	13	549	3e-08	67.8
gpu:CP009928_1108	DNA topoisomerase I [Chryseobacterium gallinarum]	23.92	418	228	12	3	392	5	360	3e-08	67.8
rs:WP_010722045	hypothetical protein [Enterococcus faecium].	34.95	103	55	3	3	98	4	101	3e-08	63.2
rs:XP_003138981	DNA topoisomerase III [Loa loa].	20.80	577	400	17	19	573	63	604	3e-08	67.4
rs:WP_008394635	MULTISPECIES: DNA topoisomerase I [Leptospira].	22.83	587	379	18	76	630	52	596	3e-08	67.4
rs:WP_004434734	DNA topoisomerase I [Leptospira noguchii].	24.34	678	378	27	3	630	4	596	3e-08	67.4
tr:A0A0D4UCW2_YEASX	SubName: Full=Top3p {ECO:0000313|EMBL:AJV58415.1};	23.95	430	257	17	188	576	229	629	3e-08	67.4
tr:G7NJ30_MACMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.48	467	292	13	188	619	239	670	3e-08	67.8
rs:WP_025619869	DNA topoisomerase I [Salinispora pacifica].	22.01	636	376	25	2	571	9	590	3e-08	67.8
rs:WP_014908638	DNA topoisomerase I [Nocardiopsis alba].	21.79	592	343	21	3	530	25	560	3e-08	67.8
rs:XP_012523359	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Monomorium pharaonis].	23.32	386	253	11	188	560	271	626	3e-08	67.8
rs:WP_031006534	DNA topoisomerase I [Streptomyces sp. NRRL F-5727].	22.58	598	331	22	2	530	13	547	3e-08	67.8
tr:A0A094HSQ5_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFZ11286.1};	21.94	629	399	25	3	560	6	613	3e-08	67.4
rs:WP_000681514	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	3e-08	67.4
rs:WP_039673374	DNA topoisomerase I [Corynebacterium minutissimum].	23.76	543	324	23	39	530	31	534	3e-08	67.8
rs:WP_000681479	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	3e-08	67.4
rs:XP_511323	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Pan troglodytes].	21.93	488	304	15	188	634	239	690	3e-08	67.8
rs:WP_016887038	DNA topoisomerase I [Mycobacterium abscessus].	24.62	597	328	26	2	530	3	545	3e-08	67.8
rs:WP_000681466	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	3e-08	67.4
rs:WP_000681404	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	3e-08	67.4
rs:WP_004498175	DNA topoisomerase I [Leptospira weilii].	24.63	613	353	25	3	579	5	544	3e-08	67.4
gp:PFU66557_1	reverse gyrase [Pyrococcus furiosus DSM 3638]	22.54	448	263	13	162	584	826	1214	3e-08	67.8
rs:WP_005394690	DNA topoisomerase I [Corynebacterium glucuronolyticum].	24.32	477	277	15	103	530	94	535	3e-08	67.8
rs:WP_046944484	DNA topoisomerase I [Leptospira santarosai].	23.50	583	380	19	76	630	52	596	3e-08	67.4
tr:A0A0D2TRF5_CRYGA	SubName: Full=Unplaced genomic scaffold supercont1.15, whole genome shotgun sequence {ECO:0000313|EMBL:KJE03532.1};	21.95	665	389	27	3	598	4	607	3e-08	67.4
tr:N1R4S4_AEGTA	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	22.67	322	206	10	188	486	186	487	3e-08	67.4
rs:XP_003279919	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Nomascus leucogenys].	22.55	470	288	15	188	619	144	575	3e-08	67.4
tr:K7MMP6_SOYBN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.58	258	168	6	64	303	302	553	3e-08	67.4
rs:WP_033286338	DNA topoisomerase I [Streptomyces sp. NRRL F-525].	22.41	598	332	21	2	530	13	547	3e-08	67.4
rs:WP_032586403	DNA topoisomerase I [Campylobacter jejuni].	22.24	652	399	23	3	618	5	584	3e-08	67.4
rs:WP_032582168	DNA topoisomerase I [Campylobacter jejuni].	22.24	652	399	23	3	618	5	584	3e-08	67.4
rs:XP_008337147	PREDICTED: DNA topoisomerase 3-like [Malus domestica].	24.78	347	217	11	3	314	8	345	3e-08	66.6
rs:WP_011819815	DNA topoisomerase I [Prochlorococcus marinus].	23.60	428	256	12	188	572	175	574	3e-08	67.4
rs:WP_028121072	DNA topoisomerase I [Epilithonimonas tenax].	22.20	572	332	19	3	538	5	499	3e-08	67.4
tr:T1DDP8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD79519.1}; Flags: Fragment;	22.77	224	149	4	307	508	1	222	3e-08	65.1
rs:WP_014410140	DNA topoisomerase I [Rickettsia montanensis].	22.64	689	411	32	1	629	1	627	3e-08	67.4
rs:WP_018821865	DNA topoisomerase I [Salinispora pacifica].	22.26	638	372	26	2	571	9	590	3e-08	67.4
rs:WP_000277558	DNA topoisomerase I [Helicobacter pylori].	22.68	485	322	14	82	537	61	521	3e-08	67.4
rs:WP_015027179	DNA topoisomerase I [Borrelia garinii].	22.98	657	383	26	2	599	5	597	3e-08	67.4
rs:WP_046951562	DNA topoisomerase I [Leptospira santarosai].	23.33	583	381	19	76	630	52	596	3e-08	67.0
tr:K7MMP5_SOYBN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.13	258	164	9	64	303	304	555	3e-08	67.4
rs:XP_012523360	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Monomorium pharaonis].	23.32	386	253	11	188	560	222	577	3e-08	67.8
rs:WP_005072605	DNA topoisomerase I [Mycobacterium abscessus].	24.62	597	328	26	2	530	3	545	3e-08	67.4
rs:WP_000681516	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	3e-08	67.4
rs:WP_000681440	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	3e-08	67.4
rs:XP_007380820	prokaryotic type I DNA topoisomerase [Punctularia strigosozonata HHB-11173 SS5].	21.73	612	412	21	3	577	4	585	3e-08	67.4
rs:WP_025906401	MULTISPECIES: DNA topoisomerase I [Prochlorococcus].	24.06	320	193	8	273	572	285	574	3e-08	67.4
rs:WP_017972909	DNA topoisomerase I [Actinopolyspora halophila].	22.67	591	338	23	2	530	28	561	3e-08	67.4
rs:WP_045924935	DNA topoisomerase I [Bifidobacterium asteroides].	21.99	632	378	24	2	571	6	584	3e-08	67.4
tr:K7MMP7_SOYBN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.13	258	164	9	64	303	304	555	3e-08	67.0
rs:WP_042606500	DNA topoisomerase III, partial [Vibrio harveyi].	26.98	252	143	9	446	671	8	244	3e-08	65.1
rs:WP_027500390	DNA topoisomerase I [Rhodococcus sp. UNC363MFTsu5.1].	23.83	600	322	23	2	530	21	556	4e-08	67.4
rs:WP_016945597	DNA topoisomerase I [Rickettsia conorii].	21.95	697	406	28	1	629	1	627	4e-08	67.4
rs:WP_018761827	DNA topoisomerase I [Arthrobacter sp. 135MFCol5.1].	22.09	584	363	22	2	538	10	548	4e-08	67.4
rs:WP_034962999	DNA topoisomerase I [Epilithonimonas sp. FH1].	22.41	580	321	20	3	538	5	499	4e-08	67.4
rs:WP_033739473	DNA topoisomerase I [Helicobacter pylori].	21.89	644	403	23	3	614	4	579	4e-08	67.4
rs:WP_005248447	DNA topoisomerase I [Rhodococcus opacus].	22.47	592	340	21	2	530	21	556	4e-08	67.4
tr:B5VNF1_YEAS6	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.90	431	256	17	188	576	51	451	4e-08	66.6
rs:WP_030998194	DNA topoisomerase I [Streptomyces sp. NRRL F-5630].	22.09	593	339	22	2	530	13	546	4e-08	67.4
tr:W6LD61_9TRYP	SubName: Full=Genomic scaffold, scaffold_17 {ECO:0000313|EMBL:CCW71839.1};	23.93	539	333	19	90	557	115	647	4e-08	67.4
rs:WP_022864544	DNA topoisomerase I [Varibaculum cambriense].	23.17	587	341	21	2	530	5	539	4e-08	67.4
tr:A0A0D0UDH7_CRYGA	SubName: Full=Unplaced genomic scaffold supercont1.1, whole genome shotgun sequence {ECO:0000313|EMBL:KIR56882.1};	21.22	655	406	24	3	598	4	607	4e-08	67.4
rs:WP_001944744	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	4e-08	67.4
rs:WP_018514247	DNA topoisomerase I [Streptomyces sp. ScaeMP-e10].	21.53	590	349	20	2	530	13	549	4e-08	67.4
rs:WP_000054703	DNA topoisomerase I [Leptospira interrogans].	23.41	675	388	25	3	630	4	596	4e-08	67.0
rs:WP_024949339	DNA topoisomerase I [Helicobacter pylori].	23.02	643	397	26	3	614	4	579	4e-08	67.4
tr:A0A0D4U6R1_YEASX	SubName: Full=Top3p {ECO:0000313|EMBL:AJV55706.1};	22.70	674	373	30	3	576	4	629	4e-08	67.0
rs:WP_006709842	DNA topoisomerase, partial [Serratia symbiotica].	30.46	197	127	5	294	481	1	196	4e-08	64.3
rs:XP_007913893	putative dna topoisomerase iii protein [Togninia minima UCRPA7].	22.20	491	311	16	67	520	2	458	4e-08	67.0
rs:WP_010549533	DNA topoisomerase I [Brachybacterium paraconglomeratum].	23.21	616	303	25	3	530	7	540	4e-08	67.4
rs:XP_002548196	conserved hypothetical protein [Candida tropicalis MYA-3404].	22.29	655	415	23	3	602	4	619	4e-08	67.0
rs:WP_033089386	hypothetical protein, partial [Nocardia seriolae].	21.81	596	342	21	2	530	24	562	4e-08	67.4
rs:WP_039918361	DNA topoisomerase I, partial [Synergistes sp. 3_1_syn1].	24.29	564	353	20	88	616	58	582	4e-08	67.0
rs:XP_003193955	DNA topoisomerase type I [Cryptococcus gattii WM276].	21.22	655	406	24	3	598	4	607	4e-08	67.4
tr:W7E2Q4_COCVI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.87	567	358	24	3	525	4	529	4e-08	67.0
rs:WP_028954489	DNA topoisomerase I [Synechocystis sp. PCC 7509].	21.36	660	395	22	2	606	4	594	4e-08	67.0
rs:WP_039683440	DNA topoisomerase I [Deinococcus swuensis].	22.85	582	346	22	3	530	5	537	4e-08	67.4
tr:H6SGW0_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.58	171	86	5	187	342	51	205	4e-08	64.3
tr:A0A0D3GFC0_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OBART06G10800.1};	29.02	224	136	7	100	303	376	596	4e-08	67.4
rs:XP_007712903	hypothetical protein COCCADRAFT_97731 [Bipolaris zeicola 26-R-13].	21.89	562	354	24	3	520	4	524	4e-08	67.0
rs:WP_000681517	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	4e-08	67.0
tr:X0QTV8_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.31	486	289	19	77	529	100	544	4e-08	67.0
tr:A0A0E0JZS3_ORYPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OPUNC02G14710.3};	22.37	617	357	27	64	610	415	979	4e-08	67.4
rs:WP_040421020	DNA topoisomerase I [Corynebacterium timonense].	23.76	543	324	20	38	530	31	533	4e-08	67.4
rs:WP_038272748	DNA topoisomerase I, partial [actinobacterium acAMD-2].	22.63	579	348	23	2	530	15	543	4e-08	67.4
rs:XP_002023181	GL21219 [Drosophila persimilis].	24.42	557	328	26	46	560	58	563	4e-08	67.4
rs:WP_037625417	DNA topoisomerase I [Streptomyces aureus].	22.86	595	333	22	2	530	13	547	4e-08	67.4
rs:WP_046300280	DNA topoisomerase I [Mycobacterium sp. UM_Kg27].	23.60	589	340	21	2	530	19	557	4e-08	67.4
rs:WP_041986539	DNA topoisomerase I [Streptomyces sp. AcH 505].	22.75	567	325	20	31	530	27	547	4e-08	67.4
rs:WP_020046071	DNA topoisomerase I [actinobacterium SCGC AAA027-M14].	23.63	584	338	23	2	530	12	542	4e-08	67.4
rs:WP_039090455	DNA topoisomerase I [Helicobacter pylori].	22.50	640	404	24	3	614	4	579	4e-08	67.0
rs:WP_030383632	DNA topoisomerase I [Streptomyces sp. NRRL S-241].	22.90	594	333	22	2	530	13	546	4e-08	67.4
rs:WP_046252353	DNA topoisomerase I [Mycobacterium chelonae].	24.66	592	328	28	2	530	3	539	4e-08	67.4
rs:WP_030095868	DNA topoisomerase I [Mycobacterium abscessus].	24.66	592	328	28	2	530	3	539	4e-08	67.4
rs:WP_024113581	DNA topoisomerase I [Helicobacter pylori].	22.48	645	398	24	3	614	4	579	4e-08	67.0
rs:XP_003051867	predicted protein [Nectria haematococca mpVI 77-13-4].	22.10	561	349	20	3	520	4	519	4e-08	67.0
tr:W4J001_PLAFP	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETW55613.1};	26.36	330	186	13	251	557	364	659	4e-08	67.0
rs:XP_007922203	hypothetical protein MYCFIDRAFT_193524 [Pseudocercospora fijiensis CIRAD86].	22.96	392	260	12	163	540	281	644	4e-08	67.0
rs:WP_026197617	DNA topoisomerase I [Sciscionella marina].	22.53	586	346	22	2	530	23	557	4e-08	67.4
rs:WP_030573656	DNA topoisomerase I [Streptomyces sclerotialus].	22.58	598	331	22	2	530	13	547	4e-08	67.4
rs:WP_033587723	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	4e-08	67.0
rs:WP_001950705	DNA topoisomerase I [Helicobacter pylori].	23.17	643	396	26	3	614	4	579	4e-08	67.0
rs:WP_000681453	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	24	3	614	4	579	4e-08	67.0
rs:WP_030043294	DNA topoisomerase I, partial [Streptomyces resistomycificus].	24.00	400	218	12	185	530	21	388	4e-08	67.0
rs:XP_007333751	hypothetical protein AGABI1DRAFT_46203 [Agaricus bisporus var. burnettii JB137-S8].	22.39	603	379	22	3	557	4	565	4e-08	67.0
rs:WP_021334812	DNA topoisomerase I subunit omega, partial [Corynebacterium diphtheriae].	22.06	612	382	20	80	643	77	641	4e-08	67.0
tr:V5BE78_TRYCR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.87	343	202	11	268	582	23	327	4e-08	67.0
rs:WP_040250119	DNA topoisomerase I [Streptomyces albus].	22.60	593	336	21	2	530	13	546	4e-08	67.0
tr:K2L3C0_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	22.48	467	312	11	99	537	77	521	4e-08	67.0
rs:WP_002860825	DNA topoisomerase I [Campylobacter jejuni].	22.09	652	400	23	3	618	5	584	4e-08	67.0
rs:WP_018845833	DNA topoisomerase I [Streptomyces sp. CNT372].	22.82	596	332	22	2	530	13	547	4e-08	67.0
rs:WP_026532947	DNA topoisomerase I [Arthrobacter sp. H41].	22.66	640	378	26	2	587	13	589	4e-08	67.0
rs:WP_020378945	hypothetical protein [Candidatus Microthrix parvicella].	22.86	595	339	23	3	530	4	545	4e-08	67.0
rs:WP_002888820	DNA topoisomerase I [Campylobacter jejuni].	22.09	652	400	23	3	618	5	584	4e-08	67.0
rs:WP_047177953	DNA topoisomerase I [Streptomyces sp. MNU77].	21.57	598	339	20	2	530	13	549	4e-08	67.0
rs:WP_011132072	DNA topoisomerase I [Prochlorococcus marinus].	24.30	428	253	13	188	572	175	574	4e-08	67.0
rs:WP_030749301	DNA topoisomerase I [Streptomyces griseus].	22.41	598	332	23	2	530	13	547	4e-08	67.0
rs:WP_023526886	DNA topoisomerase I [Helicobacter pylori].	22.27	642	403	23	3	614	4	579	4e-08	67.0
rs:WP_043371813	DNA topoisomerase I [Streptomyces mutabilis].	22.18	595	337	21	2	530	13	547	4e-08	67.0
rs:WP_024405099	hypothetical protein [Streptococcus suis].	27.53	178	113	4	514	675	27	204	4e-08	63.9
rs:WP_000681519	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	4e-08	67.0
rs:WP_014653981	DNA topoisomerase I [Borrelia garinii].	22.75	655	387	25	2	599	5	597	5e-08	67.0
rs:WP_012660909	DNA topoisomerase I [Campylobacter lari].	21.47	652	404	22	3	618	4	583	5e-08	67.0
rs:WP_046496617	DNA topoisomerase I [Streptomyces sp. NRRL B-24891].	22.15	596	336	22	2	530	13	547	5e-08	67.0
rs:WP_034973169	DNA topoisomerase I [Epilithonimonas lactis].	22.38	572	331	20	3	538	5	499	5e-08	67.0
tr:A0A0C4E714_MAGP6	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.96	563	357	19	3	519	5	525	5e-08	66.6
rs:WP_038892912	DNA topoisomerase III, partial [Vibrio campbellii].	25.23	222	151	4	349	555	17	238	5e-08	64.3
rs:WP_045538949	DNA topoisomerase I [Gordonia sp. no. 9].	23.95	593	336	23	2	530	13	554	5e-08	67.0
tr:S4TLK9_9CHLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.73	695	393	28	3	630	5	622	5e-08	67.0
tr:A0A0D1A1L6_CRYGA	SubName: Full=Unplaced genomic scaffold supercont1.1, whole genome shotgun sequence {ECO:0000313|EMBL:KIS01785.1};	21.37	655	405	24	3	598	4	607	5e-08	67.0
rs:WP_043442525	DNA topoisomerase I [Streptomyces nodosus].	22.56	585	347	20	2	530	13	547	5e-08	67.0
rs:WP_043327234	DNA topoisomerase I [Micromonospora sp. M42].	21.70	636	378	24	2	571	9	590	5e-08	67.0
tr:A0A0E0JZS1_ORYPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OPUNC02G14710.1};	21.94	629	369	27	64	610	415	1003	5e-08	67.0
tr:D7FUP7_ECTSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.47	469	315	12	188	622	13	457	5e-08	67.0
rs:WP_014410571	DNA topoisomerase I [Rickettsia parkeri].	21.81	697	407	28	1	629	1	627	5e-08	67.0
rs:WP_042963560	DNA topoisomerase I [Campylobacter coli].	22.03	649	404	23	3	618	5	584	5e-08	67.0
rs:WP_028245271	DNA topoisomerase I [Pseudoclavibacter soli].	22.55	581	348	20	2	528	6	538	5e-08	67.0
rs:WP_018958827	DNA topoisomerase I [Streptomyces sp. CNB091].	21.81	596	340	21	2	530	13	549	5e-08	67.0
tr:W7F6L4_PLAF8	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EUR65568.1};	26.36	330	186	13	251	557	363	658	5e-08	67.0
rs:WP_020122616	DNA topoisomerase I [Streptomyces canus].	22.61	597	332	22	2	530	13	547	5e-08	67.0
rs:WP_012719587	DNA topoisomerase I [Rickettsia africae].	21.95	697	406	28	1	629	1	627	5e-08	67.0
rs:WP_031046484	DNA topoisomerase I [Streptomyces sp. NRRL WC-3774].	22.65	596	333	22	2	530	13	547	5e-08	67.0
rs:WP_020129311	DNA topoisomerase I [Streptomyces sp. 303MFCol5.2].	22.20	590	343	21	2	530	13	547	5e-08	67.0
tr:A0A0D1YK20_9PEZI	SubName: Full=Verruconis gallopava strain CBS 43764 unplaced genomic scaffold supercont1.28, whole genome shotgun sequence {ECO:0000313|EMBL:KIW01217.1};	21.84	380	254	11	163	525	31	384	5e-08	66.6
rs:WP_031090918	DNA topoisomerase I [Streptomyces sp. NRRL S-15].	22.03	590	346	21	2	530	11	547	5e-08	67.0
rs:WP_001870316	DNA topoisomerase I [Helicobacter pylori].	22.90	476	299	12	99	537	77	521	5e-08	66.6
rs:WP_027691817	DNA topoisomerase I [Rathayibacter toxicus].	22.07	598	332	21	2	528	6	540	5e-08	67.0
tr:D4KD90_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	23.45	388	234	12	90	434	40	407	5e-08	66.2
tr:F3CCA9_PSESG	SubName: Full=Topoisomerase {ECO:0000313|EMBL:EGH16901.1}; Flags: Fragment;	28.94	235	147	8	100	317	8	239	5e-08	64.7
rs:WP_033523275	DNA topoisomerase I [Bifidobacterium merycicum].	21.86	645	367	24	2	571	6	588	5e-08	67.0
rs:WP_037298465	hypothetical protein [Ruminococcus flavefaciens].	36.96	92	44	3	1	87	1	83	5e-08	62.0
rs:WP_022935905	DNA topoisomerase I [Mycoplasma orale].	22.61	681	410	27	2	641	3	607	5e-08	66.6
rs:WP_010473233	DNA topoisomerase I [Streptomyces somaliensis].	22.92	397	226	12	185	530	180	547	5e-08	67.0
rs:WP_013609494	DNA topoisomerase I [Mycoplasma suis].	23.75	640	371	26	33	611	19	602	5e-08	67.0
rs:WP_037257920	DNA topoisomerase I, partial [Rhodovibrio salinarum].	20.77	703	419	26	1	629	1	639	5e-08	67.0
rs:WP_009380839	DNA topoisomerase I [Brevibacterium casei].	22.93	593	351	21	2	538	10	552	5e-08	67.0
rs:WP_002825508	DNA topoisomerase I [Campylobacter coli].	22.03	649	404	23	3	618	5	584	5e-08	66.6
rs:WP_043452439	DNA topoisomerase I [Arthrobacter phenanthrenivorans].	21.92	584	364	22	2	538	10	548	5e-08	67.0
rs:WP_005064939	DNA topoisomerase I [Mycobacterium abscessus].	24.66	596	329	26	2	530	3	545	5e-08	67.0
rs:WP_002864986	DNA topoisomerase I [Campylobacter jejuni].	22.09	652	400	23	3	618	5	584	5e-08	66.6
rs:WP_019821575	hypothetical protein, partial [Vibrio splendidus].	25.36	276	166	12	426	672	36	300	5e-08	65.5
rs:WP_000681477	DNA topoisomerase I [Helicobacter pylori].	22.71	643	399	25	3	614	4	579	5e-08	66.6
rs:XP_011652536	PREDICTED: uncharacterized protein LOC101210581 [Cucumis sativus].	25.70	358	217	16	64	385	378	722	5e-08	67.0
rs:WP_000681455	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	5e-08	66.6
rs:WP_012262322	DNA topoisomerase I [Rickettsia rickettsii].	22.11	701	400	28	1	629	1	627	5e-08	66.6
rs:WP_033614663	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	5e-08	66.6
rs:WP_000681468	DNA topoisomerase I [Helicobacter pylori].	22.50	640	404	24	3	614	4	579	5e-08	66.6
rs:WP_042253433	hypothetical protein [Lactobacillus brevis].	28.72	188	111	6	200	372	1	180	5e-08	63.5
sp:TOP3A_HUMAN	RecName: Full=DNA topoisomerase 3-alpha; EC=5.99.1.2; AltName: Full=DNA topoisomerase III alpha;	22.27	485	306	16	188	634	239	690	5e-08	67.0
rs:WP_030564994	DNA topoisomerase I [Streptomyces cyaneofuscatus].	21.81	596	340	21	2	530	13	549	5e-08	67.0
rs:WP_001030977	DNA topoisomerase I [Helicobacter pylori].	22.65	468	310	12	99	537	36	480	5e-08	66.6
rs:XP_003694833	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha [Apis florea].	22.81	570	355	21	46	577	862	1384	5e-08	67.0
sp:TOP3_CAEEL	RecName: Full=DNA topoisomerase 3; EC=5.99.1.2; AltName: Full=DNA topoisomerase III;	23.13	402	262	11	188	573	211	581	5e-08	66.6
tr:M0XQU4_HORVD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.85	334	201	13	39	344	333	644	5e-08	66.6
tr:W7VGT4_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.66	637	377	24	2	571	50	631	5e-08	67.0
rs:WP_033609574	DNA topoisomerase I [Helicobacter pylori].	22.81	640	402	25	3	614	4	579	5e-08	66.6
rs:WP_031509212	DNA topoisomerase I [Streptomyces megasporus].	23.08	611	317	20	2	530	13	552	5e-08	67.0
rs:XP_001350185	DNA topoisomerase III, putative [Plasmodium falciparum 3D7].	26.36	330	186	13	251	557	363	658	5e-08	66.6
rs:WP_000681425	DNA topoisomerase I [Helicobacter pylori].	22.81	640	402	25	3	614	4	579	5e-08	66.6
rs:WP_037690948	DNA topoisomerase I [Streptomyces atratus].	22.41	598	334	22	2	530	13	549	5e-08	67.0
rs:WP_021301973	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	24	3	614	4	579	5e-08	66.6
rs:WP_004450175	DNA topoisomerase I [Leptospira noguchii].	24.19	678	379	26	3	630	4	596	5e-08	66.6
rs:WP_022265886	DNA topoisomerase [Firmicutes bacterium CAG:449].	22.91	467	289	16	193	630	1	425	5e-08	66.2
rs:WP_038452705	DNA topoisomerase I [Campylobacter iguaniorum].	22.12	642	406	22	2	614	3	579	5e-08	66.6
tr:K1TPQ8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC75062.1}; Flags: Fragment;	33.61	119	73	2	497	611	14	130	5e-08	63.5
rs:XP_011100133	PREDICTED: DNA topoisomerase 3-alpha [Sesamum indicum].	24.44	356	202	12	256	585	282	596	5e-08	66.6
rs:WP_021300989	DNA topoisomerase I [Helicobacter pylori].	23.02	643	397	26	3	614	4	579	6e-08	66.6
rs:XP_002554555	KLTH0F08118p [Lachancea thermotolerans].	23.31	592	369	22	46	589	60	614	6e-08	66.6
rs:WP_033793824	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	6e-08	66.6
rs:WP_000681504	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	24	3	614	4	579	6e-08	66.6
rs:WP_014046845	MULTISPECIES: DNA topoisomerase I [Streptomyces].	21.79	592	345	20	2	530	13	549	6e-08	66.6
rs:WP_030446875	DNA topoisomerase I [Actinocatenispora sera].	24.85	342	214	13	250	571	274	592	6e-08	66.6
tr:A0A024VL13_PLAFA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETW29414.1}; Flags: Fragment;	26.22	328	185	12	251	555	22	315	6e-08	65.5
rs:WP_019631896	DNA topoisomerase I [Actinomadura atramentaria].	23.34	557	330	19	32	530	14	531	6e-08	66.6
rs:WP_015062158	DNA topoisomerase III [Salmonella sp. 14].	31.65	158	92	5	488	640	3	149	6e-08	63.2
rs:WP_033963794	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	23.50	400	249	13	163	537	42	409	6e-08	66.2
rs:WP_000277560	DNA topoisomerase I [Helicobacter pylori].	22.65	468	310	12	99	537	77	521	6e-08	66.6
tr:H4K211_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.84	403	257	14	295	673	1	369	6e-08	66.2
tr:A0A026VYF1_CERBI	SubName: Full=DNA topoisomerase 3-alpha {ECO:0000313|EMBL:EZA48833.1};	20.87	484	314	16	188	634	40	491	6e-08	66.6
rs:WP_017618511	DNA topoisomerase I [Nocardiopsis gilva].	22.13	601	332	22	2	530	24	560	6e-08	66.6
rs:WP_034663111	DNA topoisomerase I [Corynebacterium tuscaniense].	23.67	545	329	20	38	530	30	539	6e-08	66.6
rs:WP_001965050	DNA topoisomerase I [Helicobacter pylori].	22.46	641	403	22	3	614	4	579	6e-08	66.6
rs:XP_009252924	hypothetical protein FPSE_01529 [Fusarium pseudograminearum CS3096].	21.24	565	362	20	3	525	4	527	6e-08	66.6
rs:WP_033750475	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	6e-08	66.6
rs:WP_002869288	DNA topoisomerase I [Campylobacter jejuni].	22.09	652	400	23	3	618	5	584	6e-08	66.6
rs:XP_006624158	PREDICTED: DNA topoisomerase 3-alpha-like [Apis dorsata].	22.46	570	357	21	46	577	142	664	6e-08	66.6
rs:WP_044495900	DNA topoisomerase I, partial [Peptoclostridium difficile].	29.78	225	140	7	90	303	68	285	6e-08	64.7
tr:M3NWR8_HELPX	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EMH00087.1};	21.67	466	316	11	99	537	9	452	6e-08	66.2
tr:G3DT94_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	26.84	339	221	12	77	400	90	416	6e-08	65.9
rs:WP_020325470	hypothetical protein, partial [Pseudomonas syringae].	26.92	182	126	4	505	684	2	178	6e-08	63.5
rs:XP_002428087	DNA topoisomerase 3-alpha, putative [Pediculus humanus corporis].	21.88	480	305	16	188	643	206	639	6e-08	66.6
rs:WP_019776020	hypothetical protein, partial [Streptococcus sobrinus].	29.68	219	132	8	3	205	4	216	6e-08	63.5
tr:A0A090SHZ6_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL27226.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL27226.1};	52.31	65	27	1	161	221	14	78	6e-08	63.2
rs:WP_009189847	DNA topoisomerase I [Streptomyces sp. e14].	22.52	595	335	21	2	530	13	547	6e-08	66.6
rs:WP_000655382	DNA topoisomerase I [Helicobacter pylori].	23.64	495	313	16	83	538	55	523	6e-08	66.6
rs:WP_038831465	DNA topoisomerase I [Campylobacter coli].	21.57	649	407	21	3	618	5	584	6e-08	66.6
tr:F9EQV8_FUSNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.33	337	209	9	275	590	2	313	6e-08	65.5
rs:WP_044770463	hypothetical protein [Streptococcus suis].	27.53	178	113	4	514	675	27	204	6e-08	63.5
rs:WP_001990371	DNA topoisomerase I [Helicobacter pylori].	22.65	468	310	12	99	537	77	521	6e-08	66.2
rs:WP_002355993	DNA topoisomerase, partial [Enterococcus faecium].	23.70	211	146	3	290	490	8	213	6e-08	63.5
rs:WP_007321541	DNA topoisomerase I [Gordonia araii].	25.00	592	326	28	2	530	16	552	6e-08	66.6
tr:X0MUK6_FUSOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EXM37236.1};	21.77	565	349	19	3	520	4	522	6e-08	66.2
tr:H1VFG8_COLHI	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:CCF38971.1}; Flags: Fragment;	22.60	447	295	17	3	413	4	435	6e-08	65.9
rs:WP_020980388	DNA topoisomerase I [Leptospira noguchii].	24.19	678	379	27	3	630	4	596	6e-08	66.2
rs:WP_034709441	DNA topoisomerase I [Chryseobacterium soli].	24.16	418	227	12	3	392	5	360	6e-08	66.6
rs:WP_033601513	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	23	3	614	4	579	6e-08	66.6
rs:WP_000681478	DNA topoisomerase I [Helicobacter pylori].	22.81	640	402	25	3	614	4	579	6e-08	66.6
rs:WP_002863984	DNA topoisomerase I [Campylobacter jejuni].	21.93	652	401	23	3	618	5	584	6e-08	66.2
tr:W9N470_FUSOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EWZ99087.1};	21.77	565	349	19	3	520	4	522	6e-08	66.2
rs:WP_025063001	DNA topoisomerase I [Sulfitobacter guttiformis].	22.31	605	345	21	1	534	1	551	7e-08	66.6
rs:WP_038823346	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	22.93	410	239	13	163	537	31	398	7e-08	66.2
rs:WP_032511807	hypothetical protein [Streptococcus suis].	27.27	176	112	4	516	675	3	178	7e-08	63.2
rs:WP_019776021	hypothetical protein, partial [Streptococcus sobrinus].	29.68	219	132	8	3	205	4	216	7e-08	63.5
rs:WP_040854215	DNA topoisomerase I [Nocardia niigatensis].	22.50	560	326	20	38	530	19	537	7e-08	66.6
tr:D4K6V4_9FIRM	SubName: Full=Draft genome {ECO:0000313|EMBL:CBL00567.1};	34.94	83	47	3	30	107	13	93	7e-08	62.0
rs:WP_045915569	DNA topoisomerase I [Orientia tsutsugamushi].	23.22	577	334	20	1	534	1	511	7e-08	66.6
rs:WP_042964624	DNA topoisomerase I [Campylobacter coli].	21.73	649	406	22	3	618	5	584	7e-08	66.2
gp:HSU43431_2	DNA topoisomerase III [Homo sapiens]	22.27	485	306	16	188	634	214	665	7e-08	66.6
tr:T2SWI8_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	22.30	453	303	11	99	525	80	509	7e-08	65.9
rs:WP_029249170	DNA topoisomerase I [Mycobacterium avium].	23.60	589	340	21	2	530	16	554	7e-08	66.6
rs:WP_044452491	DNA topoisomerase I, partial [Mastigocladus laminosus].	25.32	308	190	8	267	564	2	279	7e-08	65.9
rs:WP_040163317	DNA topoisomerase I [Microbacterium sp. G3].	22.11	597	345	20	2	538	6	542	7e-08	66.6
rs:XP_005714936	DNA topoisomerase I Mitochondrial [Chondrus crispus].	23.61	538	320	19	95	582	118	614	7e-08	66.6
rs:WP_033122603	DNA topoisomerase I [Helicobacter pylori].	22.71	709	411	29	3	636	4	650	7e-08	66.2
rs:XP_009430919	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Pan troglodytes].	21.93	488	304	15	188	634	144	595	7e-08	66.6
rs:WP_011945076	DNA topoisomerase I [Orientia tsutsugamushi].	23.22	577	334	20	1	534	1	511	7e-08	66.2
rs:WP_031182736	DNA topoisomerase I [Streptomyces seoulensis].	22.39	594	337	21	2	530	13	547	7e-08	66.6
tr:W9PVS6_FUSOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EXA49324.1};	21.90	557	358	19	3	520	4	522	7e-08	66.2
rs:WP_027374086	DNA topoisomerase I [Chryseobacterium sp. UNC8MFCol].	23.92	418	228	12	3	392	5	360	7e-08	66.2
rs:WP_034737625	DNA topoisomerase I [Chryseobacterium indologenes].	23.92	418	228	12	3	392	5	360	7e-08	66.2
rs:WP_008882108	DNA topoisomerase I [Borrelia finlandensis].	24.76	622	346	27	2	565	5	562	7e-08	66.2
tr:W9NBU3_FUSOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EWZ99086.1};	21.90	557	358	19	3	520	4	522	7e-08	66.2
rs:WP_033997592	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	22.30	426	239	14	250	641	74	441	7e-08	65.9
rs:WP_011817947	DNA topoisomerase I [Prochlorococcus marinus].	25.37	335	197	12	261	572	270	574	7e-08	66.2
rs:WP_038841321	DNA topoisomerase I [Campylobacter coli].	21.73	649	406	22	3	618	5	584	7e-08	66.2
tr:W9ITG9_FUSOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EWY97962.1};	21.90	557	358	19	3	520	4	522	7e-08	66.2
rs:WP_046314796	DNA topoisomerase I [Mycobacterium sp. UM_Kg1].	22.82	631	378	22	2	571	16	598	7e-08	66.2
rs:WP_022092241	DNA topoisomerase I [Firmicutes bacterium CAG:536].	23.48	541	333	17	3	520	5	487	7e-08	66.2
rs:XP_006667060	DNA topoisomerase III [Cordyceps militaris CM01].	22.66	503	319	20	46	519	6	467	7e-08	66.2
rs:WP_037682683	DNA topoisomerase I [Streptomyces griseus].	22.28	597	334	21	2	530	13	547	7e-08	66.2
rs:WP_005924714	hypothetical protein [Faecalibacterium prausnitzii].	34.94	83	47	3	30	107	13	93	7e-08	61.6
rs:WP_012608900	DNA topoisomerase [Desulfurococcus kamchatkensis].	21.76	510	335	16	90	580	731	1195	7e-08	66.6
rs:WP_012379792	DNA topoisomerase I [Streptomyces griseus].	21.40	598	340	20	2	530	13	549	7e-08	66.2
tr:W9PW21_FUSOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EXA49323.1};	21.90	557	358	19	3	520	4	522	8e-08	66.2
rs:WP_015232464	reverse gyrase [Caldisphaera lagunensis].	23.66	503	316	14	90	571	737	1192	8e-08	66.6
tr:A0A0E0CKE3_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OMERI02G16280.2};	25.31	320	199	12	39	335	310	612	8e-08	66.2
tr:A0A024V2K8_PLAFA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETW16689.1};	26.52	328	184	13	251	555	67	360	8e-08	65.5
rs:WP_000772479	DNA topoisomerase I [Acinetobacter baumannii].	23.80	479	314	15	76	537	51	495	8e-08	65.9
rs:WP_033770665	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	8e-08	66.2
rs:WP_000681527	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	24	3	614	4	579	8e-08	66.2
tr:W7BLI4_LISGR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.09	193	116	6	154	331	1	191	8e-08	63.2
rs:WP_030503757	DNA topoisomerase I [Micromonospora purpureochromogenes].	21.94	638	374	25	2	571	9	590	8e-08	66.2
rs:WP_029027951	DNA topoisomerase I [Salinispora arenicola].	22.64	636	372	28	2	571	9	590	8e-08	66.2
tr:K8GW39_HELPX	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EKQ72915.1};	22.72	405	269	12	157	537	14	398	8e-08	65.9
rs:WP_020974013	DNA topoisomerase I [Campylobacter coli].	21.73	649	406	22	3	618	5	584	8e-08	66.2
rs:WP_000277566	DNA topoisomerase I [Helicobacter pylori].	22.86	468	309	11	99	537	77	521	8e-08	66.2
rs:WP_012877128	DNA topoisomerase I [Xylanimonas cellulosilytica].	22.43	642	380	25	2	574	4	596	8e-08	66.2
rs:WP_030764024	DNA topoisomerase I [Streptomyces sp. NRRL F-2664].	22.18	595	336	22	2	530	13	546	8e-08	66.2
rs:WP_012274955	hypothetical protein [Collimonas fungivorans].	22.66	578	363	21	90	631	74	603	8e-08	66.2
tr:W9IXD5_FUSOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EWY97960.1};	21.90	557	358	19	3	520	4	522	8e-08	66.2
rs:WP_030942456	DNA topoisomerase I [Streptomyces sp. NRRL S-646].	22.45	597	333	21	2	530	13	547	8e-08	66.2
rs:WP_031251847	DNA topoisomerase I, partial [Helicobacter pylori].	22.30	453	303	11	99	525	77	506	8e-08	65.9
rs:WP_033599198	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	24	3	614	4	579	8e-08	66.2
rs:WP_025192366	hypothetical protein [Enterococcus faecalis].	35.16	128	73	4	99	218	1	126	8e-08	62.4
rs:WP_004068124	reverse gyrase [Thermococcus litoralis].	24.78	448	248	18	162	583	827	1211	8e-08	66.2
rs:WP_003967422	DNA topoisomerase I [Streptomyces sp. ACT-1].	21.40	598	340	20	2	530	13	549	8e-08	66.2
rs:WP_018793300	DNA topoisomerase I [Salinispora arenicola].	22.64	636	372	27	2	571	9	590	8e-08	66.2
tr:A4Z8U2_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	34.01	147	74	4	188	319	57	195	8e-08	63.2
rs:WP_045913310	DNA topoisomerase I [Orientia tsutsugamushi].	23.22	577	334	20	1	534	1	511	8e-08	66.2
rs:WP_020805409	DNA topoisomerase, partial [Klebsiella pneumoniae].	32.39	142	89	5	255	391	22	161	8e-08	63.2
rs:WP_009341807	DNA topoisomerase I [Raphidiopsis brookii].	21.50	507	337	12	90	560	80	561	8e-08	66.2
rs:WP_030668102	DNA topoisomerase I [Streptomyces cellulosae].	22.24	589	344	21	2	530	13	547	8e-08	66.2
rs:WP_014364595	DNA topoisomerase I [Rickettsia philipii].	21.83	701	402	27	1	629	1	627	8e-08	66.2
rs:WP_031643907	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	23.53	374	230	12	189	537	4	346	8e-08	65.5
rs:WP_034085616	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	24.37	316	170	10	250	537	56	330	9e-08	65.5
tr:X0B8D7_FUSOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EXK41406.1};	21.77	565	349	19	3	520	4	522	9e-08	65.9
rs:WP_012149421	DNA topoisomerase I [Rickettsia akari].	22.03	699	403	28	1	629	1	627	9e-08	66.2
rs:WP_041308816	DNA topoisomerase I [Mycoplasma agalactiae].	20.64	625	413	22	38	630	20	593	9e-08	65.9
rs:WP_026403583	DNA topoisomerase I [Actinomadura rifamycini].	22.82	390	226	12	188	530	189	550	9e-08	66.2
rs:WP_000681528	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	24	3	614	4	579	9e-08	65.9
rs:WP_000681487	DNA topoisomerase I [Helicobacter pylori].	23.02	643	397	26	3	614	4	579	9e-08	65.9
rs:WP_004445466	DNA topoisomerase I [Leptospira noguchii].	24.19	678	379	26	3	630	4	596	9e-08	65.9
tr:X5DQT1_9CORY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.76	517	288	19	80	530	101	582	9e-08	66.2
rs:WP_018106628	hypothetical protein [Porphyromonas bennonis].	22.41	540	339	16	3	523	5	483	9e-08	66.2
rs:XP_003001061	DNA topoisomerase [Verticillium alfalfae VaMs.102].	22.03	572	356	21	3	519	4	540	9e-08	65.9
rs:WP_020217035	DNA topoisomerase I [Salinispora arenicola].	22.64	636	372	27	2	571	9	590	9e-08	66.2
rs:WP_045912339	DNA topoisomerase I [Orientia tsutsugamushi].	23.22	577	334	20	1	534	1	511	9e-08	66.2
rs:WP_012148895	DNA topoisomerase I [Rickettsia canadensis].	21.29	695	413	25	1	629	1	627	9e-08	66.2
sp:TOP1_RICTY	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	22.22	693	409	27	1	629	1	627	9e-08	66.2
rs:WP_020805371	toprim domain protein, partial [Klebsiella pneumoniae].	27.80	205	131	8	1	195	1	198	9e-08	63.2
rs:WP_031633891	hypothetical protein [Pseudomonas aeruginosa].	30.20	149	91	4	486	629	1	141	9e-08	62.8
tr:E2A6W4_CAMFO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.82	390	250	14	188	560	207	562	9e-08	66.2
rs:XP_005350344	PREDICTED: DNA topoisomerase 3-alpha [Microtus ochrogaster].	22.46	423	253	15	251	634	199	585	9e-08	66.2
rs:WP_033777637	DNA topoisomerase I [Helicobacter pylori].	22.65	468	310	11	99	537	77	521	9e-08	65.9
rs:WP_038551051	DNA topoisomerase I [Corynebacterium glyciniphilum].	24.76	517	288	19	80	530	81	562	9e-08	66.2
rs:WP_003448703	topoisomerase I - like protein, partial [Pseudomonas aeruginosa].	24.37	316	170	10	250	537	49	323	9e-08	65.5
rs:WP_038401936	DNA topoisomerase I [Campylobacter jejuni].	22.09	652	400	23	3	618	5	584	9e-08	65.9
rs:XP_001418273	predicted protein [Ostreococcus lucimarinus CCE9901].	21.05	399	264	12	179	557	219	586	9e-08	66.2
rs:WP_038833965	DNA topoisomerase I [Campylobacter coli].	21.73	649	406	22	3	618	5	584	9e-08	65.9
rs:XP_973578	PREDICTED: DNA topoisomerase 3-alpha [Tribolium castaneum].	22.65	490	307	21	188	637	231	688	9e-08	66.2
rs:WP_023418078	MULTISPECIES: DNA topoisomerase I [Streptomyces].	22.45	588	343	20	2	530	13	546	9e-08	66.2
rs:XP_007275049	DNA topoisomerase [Colletotrichum gloeosporioides Nara gc5].	21.17	562	358	20	3	521	4	523	9e-08	65.9
rs:WP_012150651	DNA topoisomerase I [Rickettsia rickettsii].	21.83	701	402	27	1	629	1	627	9e-08	65.9
tr:A0A090R4Q1_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL10141.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL10141.1};	52.31	65	27	1	161	221	52	116	9e-08	62.4
rs:XP_009217839	DNA topoisomerase III [Gaeumannomyces graminis var. tritici R3-111a-1].	21.17	562	357	17	3	519	5	525	9e-08	65.9
tr:D6WYH2_TRICA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.65	490	307	21	188	637	206	663	9e-08	66.2
rs:WP_013054252	DNA topoisomerase I [Mycoplasma crocodyli].	20.22	638	403	26	36	629	22	597	9e-08	65.9
rs:WP_028674581	DNA topoisomerase I [Salinispora arenicola].	22.64	636	372	27	2	571	9	590	1e-07	66.2
tr:J1RFB0_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.71	590	337	21	4	530	1	534	1e-07	66.2
rs:WP_038534859	MULTISPECIES: DNA topoisomerase I [Mycobacterium avium complex (MAC)].	22.82	596	336	23	2	530	19	557	1e-07	66.2
rs:WP_021355722	topoisomerase I [Lactobacillus crispatus].	24.24	491	291	22	3	443	5	464	1e-07	65.9
tr:R0LEQ7_STREE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.85	216	140	6	163	365	47	257	1e-07	63.9
rs:WP_029023900	DNA topoisomerase I [Salinispora arenicola].	22.64	636	372	27	2	571	9	590	1e-07	65.9
tr:G9PXX1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.29	564	353	20	88	616	137	661	1e-07	65.9
rs:WP_012184412	DNA topoisomerase I [Salinispora arenicola].	22.64	636	372	27	2	571	9	590	1e-07	65.9
tr:W4TKB6_PROAA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.65	574	315	24	32	530	4	523	1e-07	65.9
rs:WP_042855966	hypothetical protein [Escherichia coli].	29.17	192	117	7	193	367	1	190	1e-07	62.8
tr:A0A0D0SS04_CRYGA	SubName: Full=Unplaced genomic scaffold supercont2.2, whole genome shotgun sequence {ECO:0000313|EMBL:KIR35917.1};	21.22	655	406	24	3	598	4	607	1e-07	65.9
rs:WP_034585299	DNA topoisomerase I [Helicobacter magdeburgensis].	24.30	568	321	21	3	528	4	504	1e-07	65.9
rs:WP_016830088	DNA topoisomerase I [Corynebacterium diphtheriae].	24.40	496	300	18	80	530	77	542	1e-07	65.9
rs:WP_014318578	DNA topoisomerase I [Corynebacterium diphtheriae].	24.40	496	300	18	80	530	77	542	1e-07	65.9
rs:WP_014364053	DNA topoisomerase I [Rickettsia canadensis].	21.17	699	409	27	1	629	1	627	1e-07	65.9
rs:WP_018798093	DNA topoisomerase I [Salinispora arenicola].	22.33	636	374	26	2	571	9	590	1e-07	65.9
rs:WP_002880888	DNA topoisomerase I [Mycoplasma alkalescens].	22.24	598	371	19	73	630	50	593	1e-07	65.9
tr:A5IY64_MYCAP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00003390}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	20.64	625	413	22	38	630	24	597	1e-07	65.9
rs:WP_002812170	DNA topoisomerase I [Campylobacter coli].	21.73	649	406	22	3	618	5	584	1e-07	65.9
rs:WP_010643779	DNA topoisomerase I [Streptomyces sp. S4].	22.45	588	343	20	2	530	13	546	1e-07	65.9
rs:WP_010744379	hypothetical protein [Enterococcus raffinosus].	30.71	127	85	2	474	597	13	139	1e-07	62.4
rs:WP_026303763	DNA topoisomerase I [Gordonia kroppenstedtii].	23.32	596	331	25	2	530	13	549	1e-07	65.9
rs:WP_042529016	DNA topoisomerase I [Corynebacterium singulare].	24.31	543	321	24	39	530	31	534	1e-07	65.9
rs:WP_003712550	DNA topoisomerase, partial [Lactobacillus oris].	29.14	151	87	4	261	399	62	204	1e-07	63.2
rs:WP_040802949	hypothetical protein, partial [Nocardia concava].	22.32	596	339	21	2	530	24	562	1e-07	65.9
rs:WP_034443192	DNA topoisomerase I [Cloacibacillus evryensis].	24.29	564	353	20	88	616	137	661	1e-07	65.9
rs:WP_002809711	DNA topoisomerase I [Campylobacter coli].	22.05	653	401	23	2	618	4	584	1e-07	65.9
rs:WP_027841323	DNA topoisomerase I [Mastigocoleus testarum].	21.34	614	375	19	3	560	4	565	1e-07	65.9
tr:Q3EJD1_BACTI	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EAO51420.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EAO51420.1};	29.22	154	104	4	41	191	46	197	1e-07	63.2
tr:X0ACK9_FUSOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EXK41405.1};	21.90	557	358	19	3	520	4	522	1e-07	65.9
rs:WP_009679427	DNA topoisomerase I [Gordonia neofelifaecis].	23.30	588	341	22	2	530	13	549	1e-07	65.9
rs:WP_027387037	DNA topoisomerase I [Chryseobacterium gregarium].	24.16	418	227	12	3	392	5	360	1e-07	65.9
rs:WP_032953610	DNA topoisomerase I, partial [Bacteroides vulgatus].	24.77	436	266	16	200	617	2	393	1e-07	65.5
tr:A0A0C5PKD8_LACSK	SubName: Full=Lactobacillus sakei strain KCA311 plasmid pKCA54, complete sequence {ECO:0000313|EMBL:AJQ16950.1};	30.15	136	75	3	276	399	33	160	1e-07	62.8
rs:XP_011252576	PREDICTED: DNA topoisomerase 3-alpha [Camponotus floridanus].	22.82	390	250	14	188	560	255	610	1e-07	65.9
tr:F5NTM5_SHIFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.84	403	257	14	295	673	1	369	1e-07	65.5
rs:WP_025956525	DNA topoisomerase I [Prochlorococcus sp. scB243_498L10].	24.48	335	200	10	261	572	270	574	1e-07	65.9
tr:A0A0A0NL09_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.49	591	347	20	2	530	14	549	1e-07	65.9
rs:WP_019032588	DNA topoisomerase I [Salinispora arenicola].	22.64	636	372	27	2	571	9	590	1e-07	65.9
tr:A3BAP2_ORYSJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.57	224	137	7	100	303	376	596	1e-07	65.9
rs:WP_028566546	DNA topoisomerase I [Salinispora tropica].	21.86	636	377	25	2	571	9	590	1e-07	65.9
rs:WP_004491528	DNA topoisomerase I [Leptospira santarosai].	23.00	587	378	18	76	630	52	596	1e-07	65.5
rs:WP_017578818	DNA topoisomerase I [Nocardiopsis valliformis].	22.00	591	343	18	3	530	25	560	1e-07	65.9
rs:WP_012225025	DNA topoisomerase 1 [Candidatus Microthrix parvicella].	22.69	595	340	23	3	530	4	545	1e-07	65.9
rs:WP_030698222	DNA topoisomerase I [Streptomyces griseus].	22.45	588	343	20	2	530	13	546	1e-07	65.9
rs:WP_033586562	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	24	3	614	4	579	1e-07	65.9
rs:WP_011930304	DNA topoisomerase I [Calyptogena okutanii thioautotrophic gill symbiont].	26.77	325	211	9	77	391	54	361	1e-07	65.9
rs:WP_043903169	DNA topoisomerase III, partial [Kingella kingae].	33.90	118	70	2	108	225	1	110	1e-07	61.6
rs:WP_001943348	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	24	3	614	4	579	1e-07	65.9
rs:WP_010303834	DNA topoisomerase I [Synechococcus sp. CB0101].	22.88	520	331	18	96	572	87	579	1e-07	65.9
tr:A0A077XXA7_9SPHI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.14	348	225	7	187	520	4	326	1e-07	65.5
rs:WP_045803759	DNA topoisomerase I [Rickettsia endosymbiont of Ixodes pacificus].	21.66	697	408	28	1	629	1	627	1e-07	65.9
rs:WP_033239415	DNA topoisomerase I [Streptomyces griseus].	22.45	588	343	20	2	530	13	546	1e-07	65.9
rs:XP_001209597	DNA topoisomerase III [Aspergillus terreus NIH2624].	22.93	423	250	14	188	563	153	546	1e-07	65.5
rs:WP_031178411	DNA topoisomerase I [Streptomyces sp. NRRL B-3253].	22.45	588	343	20	2	530	13	546	1e-07	65.9
rs:WP_018470360	MULTISPECIES: DNA topoisomerase I [Streptomyces].	22.45	588	343	20	2	530	13	546	1e-07	65.9
rs:WP_003949667	MULTISPECIES: DNA topoisomerase I [Streptomyces].	22.45	588	343	20	2	530	13	546	1e-07	65.9
rs:WP_030309838	DNA topoisomerase I [Streptomyces albidoflavus].	22.45	588	343	20	2	530	13	546	1e-07	65.9
tr:H2MSA1_ORYLA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.55	365	248	10	188	537	218	555	1e-07	65.9
rs:WP_034963909	DNA topoisomerase I [Campylobacter hyointestinalis].	21.95	656	390	23	2	614	3	579	1e-07	65.5
rs:WP_001993203	DNA topoisomerase I [Helicobacter pylori].	22.41	607	391	22	38	614	4	560	1e-07	65.5
rs:WP_045756029	DNA topoisomerase I, partial [Sphingobacterium sp. PM2-P1-29].	24.14	348	225	7	187	520	6	328	1e-07	65.5
rs:WP_031123959	DNA topoisomerase I [Streptomyces sp. NRRL S-623].	22.02	595	340	21	2	530	13	549	1e-07	65.9
rs:WP_033524661	DNA topoisomerase I [Streptomyces galbus].	22.47	592	339	23	2	530	13	547	1e-07	65.9
tr:M1WBC5_CLAP2	SubName: Full=Related to DNA topoisomerase III {ECO:0000313|EMBL:CCE30983.1};	21.94	556	357	21	3	519	4	521	1e-07	65.5
rs:WP_047097084	DNA topoisomerase I [Chryseobacterium indologenes].	23.92	418	228	12	3	392	5	360	1e-07	65.9
rs:WP_002877023	DNA topoisomerase I [Campylobacter jejuni].	22.09	652	400	23	3	618	5	584	1e-07	65.5
rs:WP_011998550	reverse gyrase [Ignicoccus hospitalis].	23.12	372	208	12	186	533	853	1170	1e-07	65.9
rs:WP_046707521	DNA topoisomerase I [Streptomyces europaeiscabiei].	22.22	594	338	21	2	530	13	547	1e-07	65.9
rs:WP_005724842	topoisomerase I [Lactobacillus crispatus].	24.24	491	291	22	3	443	5	464	1e-07	65.9
rs:WP_020141292	DNA topoisomerase I [Streptomyces sp. 351MFTsu5.1].	22.48	596	334	22	2	530	13	547	1e-07	65.9
rs:WP_030324007	DNA topoisomerase I [Streptomyces sp. NRRL B-3229].	22.48	596	334	22	2	530	13	547	1e-07	65.9
rs:WP_012461831	DNA topoisomerase I [Orientia tsutsugamushi].	22.74	642	375	22	1	597	1	566	1e-07	65.5
rs:WP_032124739	DNA topoisomerase I [Chlamydia sp. 'Diamant'].	22.59	695	394	28	3	630	5	622	1e-07	65.9
rs:XP_005848029	hypothetical protein CHLNCDRAFT_145197 [Chlorella variabilis].	23.76	362	246	9	55	392	116	471	1e-07	65.9
rs:WP_013891077	DNA topoisomerase I [Helicobacter bizzozeronii].	23.69	498	319	16	74	537	45	515	1e-07	65.5
rs:WP_028564792	DNA topoisomerase I [Salinispora tropica].	21.86	636	377	25	2	571	9	590	1e-07	65.9
rs:WP_004452187	DNA topoisomerase I [Leptospira noguchii].	24.04	678	380	26	3	630	4	596	1e-07	65.5
rs:WP_028728978	hypothetical protein, partial [Parabacteroides gordonii].	29.45	163	104	6	517	676	2	156	1e-07	62.4
tr:T0KH08_COLGC	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EQB54737.1};	21.06	565	355	21	3	521	4	523	1e-07	65.5
tr:G7GWG8_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.80	563	324	24	32	530	14	535	1e-07	65.9
rs:WP_025913466	MULTISPECIES: DNA topoisomerase I [Prochlorococcus].	24.48	335	200	10	261	572	270	574	1e-07	65.5
rs:WP_025929859	DNA topoisomerase I [Prochlorococcus sp. scB241_528O2].	24.70	332	203	11	261	572	270	574	1e-07	65.5
rs:WP_020539370	hypothetical protein [Lewinella cohaerens].	25.55	364	239	11	157	500	132	483	1e-07	65.5
rs:WP_045915940	DNA topoisomerase I [Orientia tsutsugamushi].	22.74	642	375	22	1	597	1	566	1e-07	65.5
rs:WP_046249243	DNA topoisomerase I [Streptomyces sp. MBT28].	22.18	595	337	21	2	530	13	547	1e-07	65.9
rs:WP_047139490	DNA topoisomerase I [Streptomyces sp. KE1].	22.45	588	343	20	2	530	13	546	1e-07	65.9
rs:WP_030894263	DNA topoisomerase I [Streptomyces virginiae].	22.07	589	344	21	2	530	13	546	1e-07	65.5
rs:XP_005256833	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Homo sapiens].	22.27	485	306	16	188	634	144	595	1e-07	65.5
rs:WP_014014146	DNA topoisomerase I [Rickettsia heilongjiangensis].	21.73	681	427	25	1	629	1	627	1e-07	65.5
rs:WP_040015736	hypothetical protein [Dorea formicigenerans].	29.19	185	118	5	497	671	17	198	1e-07	62.8
tr:A0A0D0Y1P3_CRYGA	SubName: Full=Unplaced genomic scaffold supercont1.1, whole genome shotgun sequence {ECO:0000313|EMBL:KIR75350.1};	21.22	655	406	24	3	598	4	607	1e-07	65.5
rs:WP_010044211	DNA topoisomerase I [Streptomyces chartreusis].	22.48	596	334	22	2	530	13	547	1e-07	65.5
rs:WP_033422723	hypothetical protein, partial [Empedobacter brevis].	30.00	210	124	6	198	395	1	199	1e-07	64.7
rs:WP_041721131	hypothetical protein [Alkaliphilus metalliredigens].	38.04	92	55	2	100	191	4	93	1e-07	61.2
tr:B0GA82_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EDR45414.1};	29.19	185	118	5	497	671	14	195	1e-07	62.8
rs:WP_018830804	DNA topoisomerase I [Salinispora tropica].	21.86	636	377	25	2	571	9	590	1e-07	65.5
rs:WP_025959683	DNA topoisomerase I [Prochlorococcus sp. scB245a_519C7].	24.48	335	200	10	261	572	270	574	1e-07	65.5
rs:WP_013602276	DNA topoisomerase I [Arthrobacter phenanthrenivorans].	21.33	586	365	21	2	538	10	548	1e-07	65.5
rs:WP_018797736	DNA topoisomerase I [Salinispora arenicola].	22.33	636	374	26	2	571	9	590	1e-07	65.5
sp:RGYR1_SULSO	RecName: Full=Reverse gyrase 1 {ECO:0000255|HAMAP-Rule:MF_01125}; Includes: RecName: Full=Helicase {ECO:0000255|HAMAP-Rule:MF_01125}; EC=3.6.4.12 {ECO:0000255|HAMAP-Rule:MF_01125}; Includes: RecName: Full=Topoisomerase {ECO:0000255|HAMAP-Rule:MF_01125}; EC=5.99.1.3 {ECO:0000255|HAMAP-Rule:MF_01125};	24.78	557	326	23	78	582	727	1242	1e-07	65.9
rs:WP_032631710	DNA topoisomerase III, partial [Pseudomonas syringae].	28.12	128	84	1	459	578	2	129	1e-07	62.0
rs:WP_001919591	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	24	3	614	4	579	1e-07	65.5
rs:WP_035181258	hypothetical protein [Lactobacillus farraginis].	27.71	166	100	4	261	414	62	219	1e-07	62.8
rs:WP_030235859	DNA topoisomerase I [Streptomyces sp. NRRL S-455].	22.48	596	334	22	2	530	13	547	1e-07	65.5
rs:WP_015609426	DNA topoisomerase I [Streptomyces fulvissimus].	21.98	596	339	21	2	530	13	549	1e-07	65.5
tr:M1PXL0_9VIRU	SubName: Full=Topoisomerase 1 {ECO:0000313|EMBL:AGF85502.1};	23.72	489	278	19	88	521	59	507	1e-07	65.5
rs:WP_025964631	DNA topoisomerase I [Prochlorococcus sp. scB243_498P15].	24.48	335	200	10	261	572	270	574	1e-07	65.5
rs:WP_029126308	DNA topoisomerase I [Salinispora tropica].	21.86	636	377	25	2	571	9	590	1e-07	65.5
tr:B8B0L7_ORYSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.57	224	137	7	100	303	376	596	1e-07	65.5
tr:A0A0B8NKQ9_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.14	560	328	20	38	530	19	537	1e-07	65.5
rs:WP_006433359	DNA topoisomerase I [Borrelia spielmanii].	23.71	620	355	24	2	565	5	562	1e-07	65.5
tr:A9X910_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.16	171	81	7	187	342	56	206	1e-07	62.8
tr:A0A0D0VE76_CRYGA	SubName: Full=Unplaced genomic scaffold supercont1.2, whole genome shotgun sequence {ECO:0000313|EMBL:KIR43125.1};	21.22	655	406	24	3	598	4	607	1e-07	65.5
rs:WP_012717347	reverse gyrase [Sulfolobus islandicus].	25.64	550	327	23	78	582	727	1239	1e-07	65.5
rs:WP_018825445	DNA topoisomerase I [Salinispora arenicola].	22.33	636	374	26	2	571	9	590	1e-07	65.5
rs:WP_019532085	DNA topoisomerase I [Salinispora arenicola].	22.64	636	372	27	2	571	9	590	1e-07	65.5
tr:D6SZ03_GARVA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.97	431	266	11	187	571	145	555	1e-07	65.5
rs:WP_047220985	DNA topoisomerase I [Orientia tsutsugamushi].	22.55	643	375	22	1	597	1	566	1e-07	65.5
rs:WP_030495830	DNA topoisomerase I [Microtetraspora glauca].	22.41	598	332	22	2	530	13	547	1e-07	65.5
tr:A9X901_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.67	180	111	4	163	335	28	202	1e-07	62.4
rs:WP_030951013	DNA topoisomerase I [Streptomyces sp. NRRL S-481].	22.48	596	334	22	2	530	13	547	1e-07	65.5
rs:WP_025104275	DNA topoisomerase I [Microbacterium paraoxydans].	22.15	596	346	21	2	538	6	542	1e-07	65.5
rs:WP_029171452	hypothetical protein [Streptococcus suis].	26.97	178	114	4	514	675	27	204	1e-07	62.4
rs:WP_036889131	hypothetical protein, partial [Prevotella enoeca].	44.74	76	41	1	103	178	1	75	1e-07	61.2
rs:WP_032758714	DNA topoisomerase I [Streptomyces alboviridis].	21.98	596	339	21	2	530	13	549	1e-07	65.5
rs:WP_015776591	DNA topoisomerase I [Brachybacterium faecium].	22.42	611	319	25	3	530	7	545	1e-07	65.5
rs:WP_032769233	DNA topoisomerase I [Streptomyces sp. CNS654].	21.45	592	347	19	2	530	13	549	1e-07	65.5
rs:WP_032515553	DNA topoisomerase I [Prochlorococcus marinus].	23.89	314	201	8	273	572	285	574	1e-07	65.5
rs:WP_042163747	DNA topoisomerase I [Streptomyces sp. NBRC 110035].	22.82	596	332	23	2	530	13	547	1e-07	65.5
rs:WP_000681467	DNA topoisomerase I [Helicobacter pylori].	22.27	642	403	23	3	614	4	579	2e-07	65.1
tr:A0A0D0TYE8_CRYGA	SubName: Full=Unplaced genomic scaffold supercont1.25, whole genome shotgun sequence {ECO:0000313|EMBL:KIR26509.1};	21.22	655	406	24	3	598	4	607	2e-07	65.5
rs:WP_024111510	DNA topoisomerase I [Propionimicrobium sp. BV2F7].	21.13	497	312	17	188	632	177	645	2e-07	65.5
rs:WP_033494912	DNA topoisomerase I [Bifidobacterium psychraerophilum].	21.67	646	379	22	2	571	6	600	2e-07	65.5
rs:WP_046831928	DNA topoisomerase I [Xanthomonas axonopodis].	21.85	563	361	19	100	631	75	589	2e-07	65.1
rs:WP_025946641	DNA topoisomerase I [Prochlorococcus sp. scB241_528N20].	24.48	335	200	10	261	572	270	574	2e-07	65.5
rs:WP_038839415	DNA topoisomerase I [Campylobacter coli].	21.73	649	406	22	3	618	5	584	2e-07	65.1
rs:WP_007264936	DNA topoisomerase I [Streptomyces sp. C].	22.24	589	343	21	2	530	13	546	2e-07	65.5
rs:WP_019329839	MULTISPECIES: DNA topoisomerase I [Streptomyces].	22.18	595	337	21	2	530	13	547	2e-07	65.5
rs:WP_018581804	DNA topoisomerase I [Corynebacterium pilosum].	24.80	508	282	21	80	530	78	542	2e-07	65.5
rs:WP_013413183	reverse gyrase [Methanothermus fervidus].	22.34	461	258	17	89	520	727	1116	2e-07	65.5
rs:WP_000681476	DNA topoisomerase I [Helicobacter pylori].	22.54	639	405	22	3	614	4	579	2e-07	65.1
tr:F9FBF1_FUSOF	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGU85855.1};	21.59	565	350	19	3	520	4	522	2e-07	65.1
rs:WP_025975307	DNA topoisomerase I [Prochlorococcus sp. scB243_495K23].	24.48	335	200	10	261	572	270	574	2e-07	65.5
tr:L1KHS5_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.03	590	344	21	2	530	13	547	2e-07	65.5
tr:R9X7K6_LACPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.94	212	131	6	200	393	1	204	2e-07	62.4
rs:WP_022859916	DNA topoisomerase I [Bifidobacterium magnum].	21.71	585	365	19	2	538	6	545	2e-07	65.5
tr:X0IMU8_FUSOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EXL85446.1};	21.72	557	359	19	3	520	4	522	2e-07	65.1
rs:WP_025940181	MULTISPECIES: DNA topoisomerase I [Prochlorococcus].	24.48	335	200	10	261	572	270	574	2e-07	65.1
rs:WP_025880728	DNA topoisomerase I [Prochlorococcus sp. scB241_527E14].	24.48	335	200	10	261	572	270	574	2e-07	65.1
rs:WP_025922213	MULTISPECIES: DNA topoisomerase I [Prochlorococcus].	24.48	335	200	10	261	572	270	574	2e-07	65.1
rs:WP_025958268	DNA topoisomerase I [Prochlorococcus sp. scB241_527L15].	24.48	335	200	10	261	572	270	574	2e-07	65.1
rs:WP_028494947	MULTISPECIES: DNA topoisomerase I [Microbacterium].	24.09	303	180	9	258	538	269	543	2e-07	65.5
rs:WP_040694667	DNA topoisomerase I [Propionimicrobium lymphophilum].	21.64	499	307	19	188	632	177	645	2e-07	65.5
rs:WP_009647413	DNA topoisomerase I [Actinomyces sp. ICM47].	23.70	633	371	26	2	571	5	588	2e-07	65.5
rs:WP_046530015	DNA topoisomerase I [Cellulomonas sp. FA1].	22.82	596	340	25	2	530	6	548	2e-07	65.5
rs:WP_002818660	DNA topoisomerase I [Campylobacter coli].	21.57	649	407	22	3	618	5	584	2e-07	65.1
rs:WP_013473584	DNA topoisomerase I [Micromonospora sp. L5].	21.54	636	379	24	2	571	9	590	2e-07	65.5
rs:WP_036334010	DNA topoisomerase I [Modestobacter sp. KNN45-2b].	22.31	641	335	29	32	574	44	619	2e-07	65.5
tr:S2VZR6_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.64	499	307	19	188	632	185	653	2e-07	65.1
rs:WP_032782100	DNA topoisomerase I [Streptomyces albus].	21.45	592	347	19	2	530	13	549	2e-07	65.5
rs:WP_010934214	DNA topoisomerase I [Corynebacterium diphtheriae].	24.40	496	300	18	80	530	77	542	2e-07	65.5
tr:L2TJV5_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.71	590	337	21	4	530	1	534	2e-07	65.5
rs:WP_025974485	DNA topoisomerase I [Prochlorococcus sp. scB241_529J16].	24.48	335	200	10	261	572	270	574	2e-07	65.1
rs:WP_025980250	DNA topoisomerase I, partial [Prochlorococcus sp. scB243_498F21].	24.48	335	200	10	261	572	247	551	2e-07	65.1
rs:WP_028442111	DNA topoisomerase I [Streptomyces sp. DpondAA-B6].	21.92	593	343	21	2	530	13	549	2e-07	65.1
rs:WP_037877861	DNA topoisomerase I [Streptomyces sp. NTK 937].	21.92	593	343	21	2	530	13	549	2e-07	65.1
tr:A8EWX5_ARCB4	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.14	522	326	21	44	533	3	486	2e-07	65.1
rs:WP_025929208	DNA topoisomerase I [Prochlorococcus sp. scB243_496A2].	24.48	335	200	10	261	572	270	574	2e-07	65.1
rs:WP_038837322	DNA topoisomerase I [Campylobacter coli].	21.73	649	406	22	3	618	5	584	2e-07	65.1
rs:WP_028570813	DNA topoisomerase I [Salinispora tropica].	21.86	636	377	25	2	571	9	590	2e-07	65.1
rs:WP_025954428	DNA topoisomerase I [Prochlorococcus sp. scB243_498C16].	24.48	335	200	10	261	572	270	574	2e-07	65.1
rs:WP_025891467	MULTISPECIES: DNA topoisomerase I [Prochlorococcus].	24.48	335	200	10	261	572	270	574	2e-07	65.1
rs:WP_013001771	DNA topoisomerase I [Streptomyces scabiei].	22.28	597	334	22	2	530	13	547	2e-07	65.1
rs:WP_039704144	DNA topoisomerase I [Helicobacter pylori].	22.71	643	398	26	3	614	4	578	2e-07	65.1
rs:WP_037717689	DNA topoisomerase I [Streptomyces mirabilis].	22.48	596	334	22	2	530	13	547	2e-07	65.1
rs:WP_000681488	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	24	3	614	4	579	2e-07	65.1
rs:WP_029137196	DNA topoisomerase I [Nakamurella lactea].	23.08	598	336	25	2	530	12	554	2e-07	65.1
tr:A0A098DSE7_GIBZA	SubName: Full=Fusarium graminearum chromosome 4, complete genome {ECO:0000313|EMBL:CEF84269.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblFungi:CEF84269};	21.06	565	363	20	3	525	36	559	2e-07	65.1
tr:T0XX17_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	25.46	377	244	15	79	428	2	368	2e-07	64.3
rs:WP_025960898	DNA topoisomerase I [Prochlorococcus sp. scB245a_519L21].	24.48	335	200	10	261	572	270	574	2e-07	65.1
rs:WP_026459868	DNA topoisomerase I [Actinomyces suimastitidis].	23.05	629	380	24	2	571	5	588	2e-07	65.1
tr:D3XTE7_9VIBR	RecName: Full=DNA topoisomerase; EC=5.99.1.2; Flags: Fragment;	33.33	147	75	4	188	319	56	194	2e-07	62.4
rs:WP_025887608	DNA topoisomerase I [Prochlorococcus sp. scB241_526B17].	24.48	335	200	10	261	572	270	574	2e-07	65.1
rs:WP_028821435	DNA topoisomerase I [Propionimicrobium lymphophilum].	21.13	497	312	17	188	632	177	645	2e-07	65.1
tr:X1KW99_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_C00401 {ECO:0000313|EMBL:GAH97920.1}; Flags: Fragment;	23.41	393	243	12	271	639	7	365	2e-07	64.3
tr:D3XTE9_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.33	147	75	4	188	319	56	194	2e-07	62.4
rs:WP_024111853	DNA topoisomerase I [Helicobacter pylori].	21.91	639	409	21	3	614	4	579	2e-07	65.1
rs:WP_025959372	DNA topoisomerase I [Prochlorococcus sp. scB241_527I9].	24.48	335	200	10	261	572	270	574	2e-07	65.1
rs:WP_009974717	DNA topoisomerase I [Mycobacterium avium].	22.32	596	339	22	2	530	19	557	2e-07	65.1
rs:WP_028567975	DNA topoisomerase I [Salinispora tropica].	21.86	636	377	25	2	571	9	590	2e-07	65.1
rs:WP_034251254	DNA topoisomerase I, partial [Bifidobacterium crudilactis].	22.00	641	382	18	2	571	6	599	2e-07	65.1
rs:WP_012015225	MULTISPECIES: DNA topoisomerase I [Salinispora].	21.86	636	377	25	2	571	9	590	2e-07	65.1
rs:WP_036796277	DNA topoisomerase III, partial [Photobacterium phosphoreum].	31.48	108	64	4	3	106	4	105	2e-07	61.2
rs:WP_012718945	reverse gyrase [Sulfolobus islandicus].	25.45	550	328	23	78	582	727	1239	2e-07	65.1
rs:WP_025953492	DNA topoisomerase I [Prochlorococcus sp. scB243_497N18].	24.48	335	200	10	261	572	270	574	2e-07	65.1
rs:WP_017542879	DNA topoisomerase I [Nocardiopsis prasina].	22.13	592	341	18	3	530	25	560	2e-07	65.1
rs:WP_018827719	DNA topoisomerase I [Salinispora pacifica].	22.26	638	372	26	2	571	9	590	2e-07	65.1
rs:WP_012736045	reverse gyrase [Sulfolobus islandicus].	25.45	550	328	23	78	582	727	1239	2e-07	65.1
rs:WP_025962241	DNA topoisomerase I [Prochlorococcus sp. scB245a_521K15].	24.48	335	200	10	261	572	270	574	2e-07	65.1
tr:W6KNT3_9TRYP	SubName: Full=Genomic scaffold, scaffold_17 {ECO:0000313|EMBL:CCW63820.1};	22.69	542	342	16	90	560	114	649	2e-07	65.1
rs:WP_007392758	DNA topoisomerase I [Megasphaera sp. UPII 135-E].	22.76	514	324	16	163	639	191	668	2e-07	65.1
rs:WP_006898127	DNA topoisomerase I [Gordonia sihwensis].	23.78	593	337	23	2	530	13	554	2e-07	65.1
rs:WP_043367683	DNA topoisomerase I [Mycobacterium mageritense].	23.00	587	347	23	2	530	15	554	2e-07	65.1
rs:WP_002557417	DNA topoisomerase I (topA) [Borrelia burgdorferi].	24.08	623	349	26	2	565	5	562	2e-07	65.1
rs:WP_032665142	hypothetical protein [Enterobacter asburiae].	29.09	165	112	3	517	679	8	169	2e-07	61.6
tr:A0A084Q054_STACH	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFA55839.1};	21.16	553	367	18	3	520	4	522	2e-07	64.7
tr:A4Z8U3_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.33	147	75	4	188	319	56	194	2e-07	62.4
tr:A4Z8U8_9VIBR	RecName: Full=DNA topoisomerase; EC=5.99.1.2; Flags: Fragment;	33.33	147	75	4	188	319	56	194	2e-07	62.4
rs:WP_019982557	DNA topoisomerase I [Streptomyces sp. Amel2xE9].	22.35	595	336	21	2	530	13	547	2e-07	65.1
tr:F9PSB8_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.68	397	246	15	258	630	1	364	2e-07	64.3
rs:WP_018332835	hypothetical protein [Actinomycetospora chiangmaiensis].	22.61	597	336	24	2	530	69	607	2e-07	65.1
rs:XP_003290405	hypothetical protein DICPUDRAFT_37309 [Dictyostelium purpureum].	22.01	677	425	25	1	612	1	639	2e-07	65.1
rs:XP_002388836	hypothetical protein MPER_12103, partial [Moniliophthora perniciosa FA553].	24.25	433	261	17	3	394	4	410	2e-07	64.3
rs:WP_027646567	DNA topoisomerase I [Salinispora pacifica].	22.26	638	372	26	2	571	9	590	2e-07	65.1
rs:XP_002139350	DNA topoisomerase family protein [Cryptosporidium muris RN66].	23.98	392	252	13	35	394	101	478	2e-07	65.1
rs:WP_033603498	DNA topoisomerase I [Helicobacter pylori].	22.43	642	402	23	3	614	4	579	2e-07	64.7
tr:A9X8X5_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.91	158	79	5	187	329	51	196	2e-07	62.0
rs:WP_013798746	reverse gyrase [Methanotorris igneus].	24.30	395	220	16	161	536	736	1070	2e-07	65.1
rs:WP_037663076	DNA topoisomerase I [Streptomyces griseofuscus].	22.41	589	343	20	2	530	13	547	2e-07	65.1
rs:WP_032840057	DNA topoisomerase I, partial [Gardnerella vaginalis].	25.93	324	186	12	271	571	12	304	2e-07	63.9
tr:A8U1H8_9PROT	SubName: Full=Possible DNA topoisomerase {ECO:0000313|EMBL:EDP61902.1};	31.30	115	76	1	475	586	1	115	2e-07	63.5
rs:WP_033713039	MULTISPECIES: DNA topoisomerase I [Mycobacterium avium complex (MAC)].	22.32	596	339	22	2	530	19	557	2e-07	65.1
rs:XP_002366301	DNA topoisomerase III alpha, putative [Toxoplasma gondii ME49].	20.20	490	307	16	188	629	208	661	2e-07	64.7
rs:WP_031041790	DNA topoisomerase I [Streptomyces sp. NRRL F-5650].	22.18	595	337	21	2	530	13	547	2e-07	65.1
rs:WP_028830609	hypothetical protein [Proteobacteria bacterium JGI 0000113-E04].	20.42	524	323	15	88	561	97	576	2e-07	65.1
rs:WP_025940464	DNA topoisomerase I [Prochlorococcus sp. scB245a_518K17].	24.48	335	200	10	261	572	270	574	2e-07	65.1
rs:WP_030629439	MULTISPECIES: DNA topoisomerase I [Streptomyces].	21.92	593	343	21	2	530	13	549	2e-07	65.1
tr:A0A0B8QBA4_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.09	235	131	8	201	413	1	219	2e-07	63.2
rs:WP_030152667	DNA topoisomerase I [Streptomyces sp. NRRL S-244].	22.18	595	336	22	2	530	13	546	2e-07	65.1
tr:D3XTG2_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.33	147	75	4	188	319	56	194	2e-07	62.0
rs:WP_012711665	reverse gyrase [Sulfolobus islandicus].	25.45	550	328	23	78	582	727	1239	2e-07	65.1
tr:J9FBN9_WUCBA	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EJW86992.1};	20.80	577	400	17	19	573	58	599	2e-07	64.7
rs:WP_035829502	DNA topoisomerase I [Cyanobium sp. CACIAM 14].	20.89	517	340	12	96	572	87	574	2e-07	65.1
rs:WP_028192777	DNA topoisomerase I [Salinispora pacifica].	22.26	638	372	26	2	571	9	590	2e-07	65.1
rs:WP_012716359	reverse gyrase [Sulfolobus islandicus].	25.45	550	328	23	78	582	727	1239	2e-07	65.1
tr:A4Z8V3_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.33	147	75	4	188	319	57	195	2e-07	62.0
rs:WP_006910134	DNA topoisomerase I [Cyanobium sp. PCC 7001].	21.56	524	333	16	96	572	87	579	2e-07	65.1
rs:WP_025960305	DNA topoisomerase I [Prochlorococcus sp. scB245a_519E23].	24.48	335	200	10	261	572	270	574	2e-07	64.7
rs:WP_018819085	DNA topoisomerase I [Salinispora pacifica].	22.26	638	372	26	2	571	9	590	2e-07	65.1
rs:WP_025973185	DNA topoisomerase I [Prochlorococcus sp. scB241_528P18].	24.48	335	200	10	261	572	270	574	2e-07	64.7
rs:WP_014514041	reverse gyrase [Sulfolobus islandicus].	25.72	552	324	24	78	582	727	1239	2e-07	65.1
rs:WP_001928282	DNA topoisomerase I [Helicobacter pylori].	23.02	643	397	26	3	614	4	579	2e-07	64.7
rs:WP_029069541	DNA topoisomerase I [Jonesia quinghaiensis].	22.11	588	350	22	2	530	6	544	2e-07	65.1
rs:WP_023251208	DNA topoisomerase III, partial [Salmonella enterica].	39.29	84	51	0	498	581	1	84	2e-07	61.2
rs:WP_030751088	DNA topoisomerase I [Streptomyces sp. NRRL F-5135].	24.00	275	167	8	273	530	298	547	2e-07	65.1
rs:WP_018891896	DNA topoisomerase I [Streptomyces sp. CNT302].	21.80	601	344	21	2	530	13	559	2e-07	65.1
rs:WP_032524149	DNA topoisomerase I [Prochlorococcus marinus].	24.48	335	200	10	261	572	270	574	2e-07	64.7
rs:WP_040101054	DNA topoisomerase III, partial [Escherichia coli].	26.63	184	123	5	1	179	1	177	2e-07	61.6
gpu:CP011341_608	DNA topoisomerase I [Rhodococcus aetherivorans]	22.41	589	344	22	2	530	17	552	2e-07	64.7
tr:W7KQ95_9CREN	RecName: Full=Reverse gyrase {ECO:0000256|HAMAP-Rule:MF_01125, ECO:0000256|RuleBase:RU004026};	24.72	352	195	10	82	396	719	1037	2e-07	65.1
rs:XP_001847754	DNA topoisomerase 3-alpha [Culex quinquefasciatus].	22.77	470	289	18	188	619	206	639	2e-07	64.7
rs:WP_012840835	DNA topoisomerase I [Blattabacterium sp. (Blattella germanica)].	25.15	509	300	21	38	520	24	477	2e-07	64.7
rs:WP_028265367	DNA topoisomerase I [Arthrobacter sp. MA-N2].	21.40	584	367	20	2	538	10	548	2e-07	64.7
rs:WP_022861227	DNA topoisomerase I [Bifidobacterium minimum].	22.24	634	377	24	2	571	6	587	2e-07	64.7
rs:WP_044252169	hypothetical protein, partial [Chondromyces apiculatus].	23.12	359	239	8	76	406	49	398	2e-07	64.7
rs:WP_002882239	DNA topoisomerase I [Campylobacter jejuni].	21.93	652	401	23	3	618	5	584	2e-07	64.7
rs:WP_001937468	DNA topoisomerase I [Helicobacter pylori].	22.90	642	399	25	3	614	4	579	2e-07	64.7
tr:H0ABU3_HALSG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.11	129	67	4	276	395	1	120	2e-07	61.6
tr:A0A016PR83_GIBZA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EYB28185.1};	21.06	565	363	20	3	525	4	527	2e-07	64.7
rs:WP_033617937	DNA topoisomerase I [Helicobacter pylori].	22.27	642	403	23	3	614	4	579	2e-07	64.7
rs:WP_017603757	DNA topoisomerase I [Nocardiopsis alkaliphila].	21.83	591	343	18	3	530	25	559	2e-07	64.7
tr:X2N7M7_SALEN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AHO22320.1};	32.65	98	56	4	1	94	1	92	2e-07	60.5
rs:WP_044598192	DNA topoisomerase I [Campylobacter peloridis].	21.24	565	343	18	3	533	5	501	2e-07	64.7
rs:WP_030588325	DNA topoisomerase I [Streptomyces anulatus].	21.48	596	342	21	2	530	13	549	2e-07	64.7
tr:W7LY95_GIBM7	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EWG44273.1};	21.34	567	349	19	3	520	4	522	2e-07	64.7
rs:WP_015503574	topoisomerase I - like protein [Pseudomonas aeruginosa].	21.08	593	375	18	74	621	59	603	2e-07	64.3
rs:WP_027649962	DNA topoisomerase I [Salinispora pacifica].	22.26	638	372	26	2	571	9	590	2e-07	64.7
rs:WP_036914127	MULTISPECIES: DNA topoisomerase I [Prochlorococcus].	22.31	520	329	17	96	572	87	574	2e-07	64.7
rs:WP_012713906	reverse gyrase [Sulfolobus islandicus].	25.45	550	328	23	78	582	727	1239	2e-07	64.7
rs:WP_040493737	DNA topoisomerase I [Ilumatobacter nonamiensis].	24.82	419	250	16	154	530	127	522	2e-07	64.7
rs:WP_027733727	DNA topoisomerase I [Streptomyces sp. CNR698].	21.93	602	342	21	2	530	13	559	2e-07	64.7
rs:WP_013143784	DNA topoisomerase [Staphylothermus hellenicus].	22.88	520	333	22	82	580	732	1204	2e-07	64.7
rs:WP_021675255	DNA topoisomerase I [Peptostreptococcaceae bacterium oral taxon 113].	22.66	662	414	26	3	629	5	603	2e-07	64.7
rs:WP_002178555	DNA topoisomerase I [Leptospira interrogans].	24.19	678	379	27	3	630	4	596	2e-07	64.3
tr:S9U416_9TRYP	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EPY23658.1};	23.89	628	382	27	86	643	107	708	2e-07	64.7
rs:WP_037955360	DNA topoisomerase I [Streptomyces sp. PRh5].	21.57	612	337	21	2	530	14	565	3e-07	64.7
rs:WP_033603417	hypothetical protein [Enterococcus faecium].	29.25	147	90	3	543	675	10	156	3e-07	61.2
rs:WP_011849376	topoisomerase [Pyrobaculum calidifontis].	21.18	510	294	17	55	536	741	1170	3e-07	64.7
tr:W5IAU1_WHEAT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.24	317	188	12	39	327	289	584	3e-07	64.3
rs:WP_007101752	DNA topoisomerase I [Synechococcus sp. RS9917].	21.26	522	344	14	90	572	81	574	3e-07	64.7
rs:WP_022410775	DNA topoisomerase [Ruminococcus sp. CAG:330].	23.76	362	232	11	273	616	13	348	3e-07	63.9
rs:WP_028416080	DNA topoisomerase I [Streptomyces sp. SolWspMP-sol2th].	21.62	592	346	20	2	530	13	549	3e-07	64.7
tr:A0A0B7J660_PHOPO	SubName: Full=ANT-220, BDW_PPBDW_I_Contig_2, whole genome shotgun sequence {ECO:0000313|EMBL:CEO38566.1};	31.48	108	64	4	3	106	4	105	3e-07	61.6
rs:WP_025479034	membrane protein, partial [Enterococcus faecium].	40.78	103	57	1	103	201	3	105	3e-07	61.2
rs:WP_010143115	DNA topoisomerase I [Citricoccus sp. CH26A].	21.97	578	362	18	2	530	9	546	3e-07	64.7
rs:WP_030817511	DNA topoisomerase I [Streptomyces sp. NRRL S-98].	21.90	589	345	21	2	530	13	546	3e-07	64.7
rs:WP_045298032	DNA topoisomerase I [Microbacterium trichothecenolyticum].	23.92	301	185	8	257	538	272	547	3e-07	64.7
tr:D4JZZ4_9FIRM	SubName: Full=Faecalibacterium prausnitzii L2/6 draft genome {ECO:0000313|EMBL:CBK99593.1};	34.94	83	47	3	30	107	13	93	3e-07	60.1
rs:WP_011316928	DNA topoisomerase I [Anabaena variabilis].	21.65	508	335	13	90	560	80	561	3e-07	64.7
rs:WP_012953015	reverse gyrase [Sulfolobus islandicus].	25.45	550	328	23	78	582	727	1239	3e-07	64.7
rs:WP_016627780	hypothetical protein [Enterococcus faecium].	40.78	103	57	1	103	201	3	105	3e-07	61.2
rs:WP_004470045	DNA topoisomerase I [Leptospira santarosai].	23.33	583	381	19	76	630	52	596	3e-07	64.3
rs:WP_046419014	DNA topoisomerase I [Streptomyces sp. MUSC136T].	22.41	589	343	20	2	530	13	547	3e-07	64.7
tr:A0A084AY93_STACH	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KEY70272.1};	21.16	553	367	18	3	520	33	551	3e-07	64.3
rs:WP_030866109	DNA topoisomerase I [Streptomyces sp. NRRL F-2747].	21.98	596	336	22	2	530	13	546	3e-07	64.7
rs:WP_025926091	DNA topoisomerase I [Prochlorococcus sp. scB241_528J8].	23.75	320	194	8	273	572	285	574	3e-07	64.7
tr:I6HI63_SHIFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	21.84	403	257	14	295	673	1	369	3e-07	63.9
rs:WP_033620616	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	24	3	614	4	579	3e-07	64.3
rs:WP_039455829	DNA topoisomerase I [endosymbiont of Acanthamoeba sp. UWC36].	23.25	684	415	23	1	630	1	628	3e-07	64.3
rs:WP_006378418	DNA topoisomerase I [Streptomyces turgidiscabies].	22.28	588	345	22	2	530	13	547	3e-07	64.7
rs:WP_028954508	DNA topoisomerase I [Synechocystis sp. PCC 7509].	22.69	476	260	19	157	575	135	559	3e-07	64.3
tr:T5AB99_OPHSC	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EQL02720.1};	21.39	561	356	21	3	520	4	522	3e-07	64.3
rs:WP_027123483	DNA topoisomerase I [Mycoplasma molare].	21.01	633	397	18	39	629	24	595	3e-07	64.3
rs:WP_007844344	MULTISPECIES: DNA topoisomerase I [Chryseobacterium].	23.68	418	229	13	3	392	5	360	3e-07	64.7
rs:WP_018811834	DNA topoisomerase I [Salinispora pacifica].	22.26	638	372	26	2	571	9	590	3e-07	64.7
rs:WP_040580726	DNA topoisomerase I [Porphyromonas endodontalis].	23.91	506	304	20	3	480	7	459	3e-07	64.3
rs:WP_018222494	DNA topoisomerase I [Salinispora pacifica].	22.26	638	372	26	2	571	9	590	3e-07	64.7
rs:WP_002353995	DNA topoisomerase, partial [Enterococcus faecium].	22.88	236	167	3	250	475	31	261	3e-07	62.4
rs:WP_000277569	DNA topoisomerase I [Helicobacter pylori].	22.86	468	309	11	99	537	77	521	3e-07	64.3
rs:WP_018206960	DNA topoisomerase I [actinobacterium SCGC AAA024-D14].	23.68	587	336	26	1	530	9	540	3e-07	64.7
rs:WP_000681502	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	24	3	614	4	579	3e-07	64.3
rs:WP_011935078	DNA topoisomerase I [Synechococcus sp. RCC307].	21.30	615	370	20	3	560	5	562	3e-07	64.7
tr:A0A0D2A347_9PEZI	SubName: Full=Verruconis gallopava strain CBS 43764 unplaced genomic scaffold supercont1.28, whole genome shotgun sequence {ECO:0000313|EMBL:KIW01218.1};	22.19	347	235	10	188	525	15	335	3e-07	63.9
rs:XP_006746431	PREDICTED: DNA topoisomerase 3-beta-1-like [Leptonychotes weddellii].	22.94	340	221	12	256	585	23	331	3e-07	64.3
rs:WP_017947790	DNA topoisomerase I [Streptomyces sp. CNS615].	21.93	602	342	21	2	530	13	559	3e-07	64.7
rs:XP_011326353	hypothetical protein FGSG_06716 [Fusarium graminearum PH-1].	21.06	565	363	20	3	525	4	527	3e-07	64.3
rs:WP_000681501	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	24	3	614	4	579	3e-07	64.3
rs:WP_014024034	DNA topoisomerase I [Borrelia bissettii].	23.95	622	351	26	2	565	5	562	3e-07	64.3
rs:WP_030228518	DNA topoisomerase I [Streptomyces lavendulae].	22.15	596	335	22	2	530	13	546	3e-07	64.7
rs:WP_014512774	reverse gyrase [Sulfolobus islandicus].	25.45	550	328	23	78	582	727	1239	3e-07	64.7
rs:WP_008743043	DNA topoisomerase I [Streptomyces sp. Mg1].	21.73	589	346	21	2	530	13	546	3e-07	64.7
rs:WP_046284851	DNA topoisomerase I [Mycobacterium sp. UM_NZ2].	23.43	589	341	22	2	530	19	557	3e-07	64.3
rs:WP_015581309	Reverse gyrase TopR1 [Sulfolobus islandicus].	25.45	550	328	23	78	582	727	1239	3e-07	64.7
rs:WP_027658068	DNA topoisomerase I [Salinispora pacifica].	22.26	638	372	26	2	571	9	590	3e-07	64.3
tr:K1U3X4_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EKC79967.1}; Flags: Fragment;	24.74	190	117	5	433	616	5	174	3e-07	61.2
rs:WP_002780003	DNA topoisomerase I [Campylobacter coli].	21.57	649	407	22	3	618	5	584	3e-07	64.3
rs:WP_010255713	DNA topoisomerase I [Borrelia burgdorferi].	24.32	625	345	27	2	565	5	562	3e-07	64.3
rs:WP_018727569	DNA topoisomerase I [Salinispora pacifica].	22.26	638	372	26	2	571	9	590	3e-07	64.3
rs:WP_033310216	DNA topoisomerase I [Streptomyces iakyrus].	21.73	589	347	21	2	530	13	547	3e-07	64.3
rs:WP_016951059	DNA topoisomerase I [Anabaena sp. PCC 7108].	20.15	521	351	12	90	572	80	573	3e-07	64.3
rs:WP_030811373	DNA topoisomerase I [Streptomyces sp. NRRL F-2799].	22.39	594	337	21	2	530	13	547	3e-07	64.3
rs:WP_024817958	DNA topoisomerase I [Arthrobacter sp. 31Y].	21.58	584	366	22	2	538	10	548	3e-07	64.3
rs:WP_005727291	topoisomerase I [Lactobacillus crispatus].	25.15	489	289	22	3	443	5	464	3e-07	64.3
rs:WP_031496005	DNA topoisomerase I [Bryobacter aggregatus].	22.67	494	312	14	77	530	69	532	3e-07	64.3
rs:WP_046260314	DNA topoisomerase I [Streptomyces sp. WM6386].	22.24	589	344	21	2	530	13	547	3e-07	64.3
rs:WP_002316997	hypothetical protein [Enterococcus faecium].	40.78	103	57	1	103	201	3	105	3e-07	60.8
rs:WP_025939426	DNA topoisomerase I [Prochlorococcus sp. scB245a_520B18].	24.25	334	202	10	261	572	270	574	3e-07	64.3
rs:WP_045698289	DNA topoisomerase I [Streptomyces rubellomurinus].	22.20	599	335	22	2	530	12	549	3e-07	64.3
rs:XP_001611286	DNA topoisomerase family protein [Babesia bovis].	21.64	647	391	29	3	585	5	599	3e-07	64.3
rs:XP_010703264	DNA topoisomerase III, putative [Leishmania panamensis].	20.30	675	442	24	3	621	5	639	3e-07	64.3
tr:A0A084RTP3_STACH	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFA79578.1};	21.52	553	365	18	3	520	33	551	3e-07	64.3
rs:WP_003456151	topoisomerase I - like protein, partial [Pseudomonas aeruginosa].	24.33	300	190	8	250	537	49	323	3e-07	63.5
rs:WP_030299335	DNA topoisomerase I [Streptomyces katrae].	22.18	595	336	22	2	530	13	546	3e-07	64.3
rs:WP_033771067	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	24	3	614	4	579	3e-07	64.3
rs:WP_019888308	DNA topoisomerase I [Streptomyces purpureus].	22.37	590	341	21	2	530	13	546	3e-07	64.3
tr:C3JAB5_9PORP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.91	506	304	20	3	480	56	508	3e-07	64.3
rs:WP_031307068	DNA topoisomerase I [Brachybacterium muris].	22.24	580	351	21	3	530	7	538	3e-07	64.3
tr:A0A0D0XTS2_CRYGA	SubName: Full=Unplaced genomic scaffold supercont2.1, whole genome shotgun sequence {ECO:0000313|EMBL:KIR89043.1};	21.95	665	389	27	3	598	4	607	3e-07	64.3
tr:G9N9J3_HYPVG	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHK16612.1};	21.99	564	346	21	3	520	4	519	3e-07	64.3
rs:XP_007822225	DNA topoisomerase [Metarhizium robertsii ARSEF 23].	22.56	430	278	16	3	394	4	416	3e-07	64.3
rs:WP_002822893	DNA topoisomerase I [Campylobacter coli].	21.57	649	407	22	3	618	5	584	3e-07	64.3
rs:WP_045255925	DNA topoisomerase I [Microbacterium hydrocarbonoxydans].	22.22	414	222	13	186	538	158	532	3e-07	64.3
rs:WP_013115817	DNA topoisomerase I [Cellulomonas flavigena].	21.92	447	265	16	186	574	174	594	3e-07	64.3
rs:WP_014309924	DNA topoisomerase I [Corynebacterium diphtheriae].	22.22	612	381	21	80	643	77	641	3e-07	64.3
rs:WP_044306347	DNA topoisomerase I [Campylobacter jejuni].	21.93	652	401	23	3	618	5	584	3e-07	64.3
tr:F2BVU5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.68	366	238	12	88	428	102	458	3e-07	63.5
rs:WP_002983696	DNA topoisomerase I [Chryseobacterium gleum].	23.68	418	229	12	3	392	5	360	3e-07	64.3
tr:A0NHW6_OENOE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.98	193	116	6	198	375	1	185	3e-07	61.6
rs:WP_000681503	DNA topoisomerase I [Helicobacter pylori].	22.74	642	400	24	3	614	4	579	3e-07	64.3
tr:A0A017SV25_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.12	359	239	8	76	406	55	404	3e-07	64.3
rs:WP_042697994	reverse gyrase [Thermococcus sp. PK].	24.61	447	250	17	162	583	827	1211	3e-07	64.3
rs:WP_033296544	DNA topoisomerase I [Streptomyces atroolivaceus].	21.53	590	349	21	2	530	11	547	3e-07	64.3
rs:WP_041594953	DNA topoisomerase I, partial [Helicobacter cetorum].	22.68	463	316	12	99	537	77	521	3e-07	63.9
rs:WP_010996931	DNA topoisomerase I [Nostoc sp. PCC 7120].	21.21	514	342	13	90	566	80	567	3e-07	64.3
tr:Q1PJN8_PROMR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	24.48	335	200	10	261	572	128	432	3e-07	64.3
tr:A0A016UM26_9BILA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EYC15966.1};	21.65	545	357	17	88	592	116	630	3e-07	64.3
rs:XP_003296497	hypothetical protein PTT_06616 [Pyrenophora teres f. teres 0-1].	23.54	446	262	15	3	394	5	425	3e-07	63.9
sp:TOP1_BORBU	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.32	625	345	27	2	565	5	562	3e-07	64.3
rs:WP_045563060	DNA topoisomerase I [Streptomyces sp. FxanaA7].	21.69	590	346	21	2	530	13	547	3e-07	64.3
rs:WP_014317501	DNA topoisomerase I [Corynebacterium diphtheriae].	24.19	496	301	18	80	530	77	542	3e-07	64.3
rs:WP_031140379	MULTISPECIES: DNA topoisomerase I [Streptomyces].	21.92	593	341	21	2	530	13	547	3e-07	64.3
tr:A0A074XH50_9PEZI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.87	567	356	19	3	520	6	534	3e-07	63.9
tr:A0A016UL69_9BILA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EYC15965.1};	21.65	545	357	17	88	592	96	610	3e-07	64.3
rs:WP_032513341	DNA topoisomerase I [Prochlorococcus marinus].	23.75	320	194	8	273	572	285	574	3e-07	64.3
rs:WP_002953849	DNA topoisomerase I [Campylobacter showae].	22.51	653	396	22	3	618	4	583	3e-07	63.9
tr:A0A028K2S0_TRIRU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.64	513	332	16	46	525	6	481	3e-07	63.9
tr:A0A0D2UDE4_GOSRA	SubName: Full=Gossypium raimondii chromosome 10, whole genome shotgun sequence {ECO:0000313|EMBL:KJB66051.1}; Flags: Fragment;	25.90	251	169	7	64	303	316	560	3e-07	63.9
rs:WP_000681525	DNA topoisomerase I [Helicobacter pylori].	21.91	639	409	22	3	614	4	579	3e-07	64.3
tr:A9X8Z3_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.99	171	83	6	187	342	56	206	3e-07	61.6
tr:A9X8X8_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.99	171	83	6	187	342	54	204	3e-07	61.2
rs:WP_030606321	DNA topoisomerase I [Streptomyces achromogenes].	22.28	597	334	23	2	530	13	547	3e-07	64.3
rs:WP_030867797	DNA topoisomerase I [Streptomyces violaceoruber].	22.18	595	337	21	2	530	13	547	3e-07	64.3
rs:WP_014307889	DNA topoisomerase I [Corynebacterium diphtheriae].	24.19	496	301	18	80	530	77	542	3e-07	64.3
rs:WP_031839728	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	25.82	337	211	11	75	389	86	405	4e-07	63.5
rs:WP_010532720	DNA topoisomerase I [Brachybacterium squillarum].	22.02	604	323	24	3	530	7	538	4e-07	64.3
tr:X0YP46_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_L01696 {ECO:0000313|EMBL:GAG58034.1}; Flags: Fragment;	26.27	335	216	9	85	392	59	389	4e-07	63.5
rs:WP_018102164	MULTISPECIES: DNA topoisomerase I [Streptomyces].	22.17	600	333	22	2	530	13	549	4e-07	64.3
rs:WP_039933303	DNA topoisomerase I [Streptomyces viridochromogenes].	22.48	596	334	22	2	530	13	547	4e-07	64.3
rs:WP_030781823	DNA topoisomerase I [Streptomyces lavenduligriseus].	22.61	597	332	23	2	530	13	547	4e-07	64.3
rs:WP_038855449	DNA topoisomerase I [Campylobacter coli].	21.57	649	407	22	3	618	5	584	4e-07	63.9
rs:WP_030972245	DNA topoisomerase I [Streptomyces sp. NRRL S-1824].	21.50	600	337	22	2	530	13	549	4e-07	64.3
rs:WP_045805442	DNA topoisomerase I [Rickettsia argasii].	21.59	681	428	25	1	629	1	627	4e-07	63.9
rs:WP_044169489	DNA topoisomerase I [Porphyromonas catoniae].	22.64	530	351	16	1	521	1	480	4e-07	63.9
rs:WP_002662118	DNA topoisomerase 1 [Borrelia burgdorferi].	24.32	625	345	27	2	565	5	562	4e-07	64.3
rs:WP_012597414	DNA topoisomerase I [Borrelia burgdorferi].	24.32	625	345	27	2	565	5	562	4e-07	64.3
rs:WP_021335436	DNA topoisomerase I subunit omega [Corynebacterium diphtheriae].	24.19	496	301	18	80	530	77	542	4e-07	64.3
tr:A0A0B4G022_9HYPO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KID79810.1}; Flags: Fragment;	22.38	429	280	15	3	394	4	416	4e-07	63.9
rs:WP_018551170	DNA topoisomerase I [Streptomyces sp. ATexAB-D23].	22.07	598	336	21	2	530	13	549	4e-07	64.3
rs:WP_009529178	topoisomerase [Peptostreptococcaceae bacterium CM5].	37.36	91	57	0	497	587	16	106	4e-07	60.1
rs:WP_025443402	DNA topoisomerase I [Borrelia miyamotoi].	23.92	418	238	14	188	560	175	557	4e-07	63.9
rs:WP_013130084	DNA topoisomerase [Thermosphaera aggregans].	22.68	538	340	21	79	591	723	1209	4e-07	64.3
tr:A0A0A1G6T4_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.91	158	79	5	187	329	51	196	4e-07	61.2
rs:WP_003850467	DNA topoisomerase I [Corynebacterium diphtheriae].	24.19	496	301	18	80	530	77	542	4e-07	64.3
tr:X1LXD9_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S08239 {ECO:0000313|EMBL:GAI23743.1}; Flags: Fragment;	25.27	273	173	9	253	520	2	248	4e-07	62.0
rs:WP_039403381	DNA topoisomerase I, partial [Microbacterium mangrovi].	22.16	388	233	11	186	530	178	539	4e-07	64.3
rs:WP_002815000	DNA topoisomerase I [Campylobacter coli].	21.57	649	407	22	3	618	5	584	4e-07	63.9
tr:A0A022ZXE0_TRIRU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.64	513	332	16	46	525	6	481	4e-07	63.9
tr:I0EUF2_HELCM	SubName: Full=Topoisomerase I {ECO:0000313|EMBL:AFI06571.1};	22.68	463	316	12	99	537	77	521	4e-07	63.5
tr:A0A0A1G827_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.87	182	96	6	163	329	27	195	4e-07	61.2
tr:A9X953_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.99	171	83	6	187	342	53	203	4e-07	61.2
rs:WP_034942599	DNA topoisomerase I [Geodermatophilaceae bacterium URHB0062].	22.20	635	346	26	32	574	50	628	4e-07	64.3
tr:F9WKC3_TRYVY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.13	407	250	12	188	564	91	456	4e-07	63.9
rs:WP_046940202	hypothetical protein, partial [Xanthomonas euvesicatoria].	27.78	126	76	4	2	113	10	134	4e-07	60.5
rs:WP_030342291	DNA topoisomerase I [Streptomyces floridae].	21.61	597	340	21	2	530	13	549	4e-07	64.3
rs:WP_032517561	DNA topoisomerase I [Prochlorococcus marinus].	24.77	331	206	11	260	572	269	574	4e-07	63.9
rs:WP_045250685	DNA topoisomerase I [Microbacterium azadirachtae].	22.84	591	355	23	2	538	6	549	4e-07	63.9
tr:D9X3Y8_STRVR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.48	596	334	22	2	530	26	560	4e-07	63.9
tr:A0A0A1G6R9_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.87	182	96	6	163	329	26	194	4e-07	61.2
tr:E2Q9N0_STRC2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.09	593	343	21	2	530	27	564	4e-07	63.9
rs:WP_014316296	DNA topoisomerase I [Corynebacterium diphtheriae].	24.19	496	301	18	80	530	77	542	4e-07	63.9
rs:WP_014302829	DNA topoisomerase I [Corynebacterium diphtheriae].	24.19	496	301	18	80	530	77	542	4e-07	63.9
rs:WP_028702223	DNA topoisomerase I [Propionibacterium jensenii].	22.03	590	346	23	3	530	7	544	4e-07	63.9
rs:WP_018788790	DNA topoisomerase I [Micromonospora sp. CNB394].	21.54	636	379	24	2	571	9	590	4e-07	63.9
tr:F9WNR1_TRYVY	SubName: Full=DNA topoisomerase, putative {ECO:0000313|EMBL:CCD19182.1};	21.57	547	366	18	46	564	8	519	4e-07	63.9
rs:WP_026824281	hypothetical protein, partial [Arsenophonus nasoniae].	28.03	132	64	3	1	118	1	115	4e-07	60.5
tr:A0A061NPI5_9BACL	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAK04502.1};	40.00	90	54	0	90	179	1	90	4e-07	60.1
tr:A0A0A1G3K6_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.91	158	79	5	187	329	50	195	4e-07	61.2
tr:A0A0A1G465_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.91	158	79	5	187	329	50	195	4e-07	61.2
rs:WP_011775956	DNA topoisomerase I [Arthrobacter aurescens].	21.92	584	364	21	2	538	10	548	4e-07	63.9
rs:WP_002542335	DNA topoisomerase I [Propionibacterium acnes].	22.19	604	323	24	3	530	7	539	4e-07	63.9
tr:A4Z8V5_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.65	147	76	4	188	319	56	194	4e-07	61.2
rs:WP_030898447	DNA topoisomerase I [Streptomyces sp. NRRL F-5126].	22.70	511	299	16	77	530	76	547	4e-07	63.9
rs:WP_031138477	DNA topoisomerase I [Streptomyces xanthophaeus].	22.15	596	335	22	2	530	13	546	4e-07	63.9
rs:WP_023955026	topoisomerase IA [Microbacterium sp. TS-1].	21.99	523	304	19	77	538	68	547	4e-07	63.9
rs:WP_011862458	DNA topoisomerase I [Prochlorococcus marinus].	24.24	330	207	10	261	572	270	574	4e-07	63.9
tr:A0A031LJZ3_9CREN	RecName: Full=Reverse gyrase {ECO:0000256|HAMAP-Rule:MF_01125, ECO:0000256|RuleBase:RU004026};	24.40	504	291	18	79	533	715	1177	4e-07	64.3
rs:WP_009996581	DNA topoisomerase I [Streptomyces clavuligerus].	22.09	593	343	21	2	530	13	550	4e-07	63.9
tr:F2SZF7_TRIRC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.64	513	332	16	46	525	6	481	4e-07	63.9
rs:WP_002522977	DNA topoisomerase I [Propionibacterium acnes].	23.22	590	334	24	3	530	7	539	4e-07	63.9
rs:WP_035863952	DNA topoisomerase I [Kitasatospora cheerisanensis].	22.58	598	333	22	2	530	12	548	4e-07	63.9
rs:WP_034685923	DNA topoisomerase I [Chryseobacterium piperi].	23.92	418	228	13	3	392	5	360	4e-07	63.9
rs:WP_031280416	DNA topoisomerase III, partial [Peptoclostridium difficile].	37.18	78	43	2	3	79	15	87	4e-07	59.3
tr:A9X8X2_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.58	171	82	6	187	342	56	206	4e-07	61.2
rs:WP_015658842	DNA topoisomerase 1 [Streptomyces davawensis].	22.07	589	345	21	2	530	13	547	4e-07	63.9
rs:WP_003975392	DNA topoisomerase I [Streptomyces lividans].	22.18	595	337	21	2	530	13	547	4e-07	63.9
sp:TOP1_STRCO	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	22.18	595	337	21	2	530	13	547	4e-07	63.9
tr:H2WE23_CAEJA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.74	409	255	14	188	573	211	581	4e-07	63.9
rs:WP_030334395	DNA topoisomerase I [Streptomyces sp. NRRL B-1381].	21.57	598	339	20	2	530	13	549	4e-07	63.9
rs:WP_040794088	DNA topoisomerase I [Nocardia higoensis].	22.64	605	325	22	4	530	1	540	4e-07	63.9
tr:A0A023ASA2_TRIRU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.64	513	332	16	46	525	7	482	4e-07	63.5
rs:WP_028708795	DNA topoisomerase I [Propionicicella superfundia].	22.89	629	358	26	2	560	8	579	4e-07	63.9
rs:WP_043247813	DNA topoisomerase I [Streptomyces vinaceus].	21.57	598	339	20	2	530	13	549	4e-07	63.9
rs:WP_045711205	DNA topoisomerase I [Streptomyces rubellomurinus].	22.37	599	334	23	2	530	12	549	4e-07	63.9
tr:K1TJK5_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EKC59411.1}; Flags: Fragment;	24.08	407	226	14	187	550	19	385	4e-07	62.8
rs:XP_003231628	DNA topoisomerase III [Trichophyton rubrum CBS 118892].	21.64	513	332	16	46	525	7	482	4e-07	63.5
rs:WP_021675961	hypothetical protein, partial [Peptostreptococcaceae bacterium oral taxon 113].	38.00	100	54	1	497	596	10	101	4e-07	59.7
rs:XP_003791095	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha [Otolemur garnettii].	22.06	467	300	16	188	619	239	676	4e-07	63.9
rs:WP_018160535	DNA topoisomerase I [Smaragdicoccus niigatensis].	22.96	588	342	22	2	530	17	552	4e-07	63.9
rs:WP_006126427	MULTISPECIES: DNA topoisomerase I [Streptomyces].	21.11	592	349	19	2	530	13	549	4e-07	63.9
tr:A0A0D2V9F9_GOSRA	SubName: Full=Gossypium raimondii chromosome 10, whole genome shotgun sequence {ECO:0000313|EMBL:KJB66050.1}; Flags: Fragment;	25.90	251	169	7	64	303	369	613	4e-07	63.5
tr:A0A0A1G831_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.87	182	96	6	163	329	28	196	4e-07	60.8
rs:WP_010010269	topoisomerase I [Lactobacillus coryniformis].	30.48	105	71	1	479	581	1	105	4e-07	60.8
rs:WP_033274891	MULTISPECIES: DNA topoisomerase I [Actinomycetales].	22.48	596	334	21	2	530	13	547	4e-07	63.9
rs:WP_002519968	MULTISPECIES: DNA topoisomerase I [Propionibacterium].	22.19	604	323	24	3	530	7	539	4e-07	63.9
rs:WP_033789637	DNA topoisomerase I [Helicobacter pylori].	22.59	642	401	24	3	614	4	579	5e-07	63.5
rs:WP_030189603	MULTISPECIES: DNA topoisomerase I [Streptomyces].	21.57	598	339	20	2	530	13	549	5e-07	63.9
rs:WP_030113344	MULTISPECIES: DNA topoisomerase I [Streptomyces].	21.57	598	339	20	2	530	13	549	5e-07	63.9
rs:WP_025941380	DNA topoisomerase I [Prochlorococcus sp. scB245a_518O7].	24.48	335	200	10	261	572	270	574	5e-07	63.9
rs:WP_030724800	MULTISPECIES: DNA topoisomerase I [Streptomyces].	21.57	598	339	20	2	530	13	549	5e-07	63.9
tr:V5UWP9_9VIBR	SubName: Full=Topoisomerase I {ECO:0000313|EMBL:AHB81954.1}; Flags: Fragment;	33.80	142	71	4	186	312	7	140	5e-07	60.1
tr:A4Z8U6_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.65	147	76	4	188	319	56	194	5e-07	61.2
tr:D3XTD9_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.65	147	76	4	188	319	54	192	5e-07	60.8
rs:WP_043404297	DNA topoisomerase I [Streptomyces pluripotens].	22.52	595	335	22	2	530	13	547	5e-07	63.9
rs:WP_030692562	DNA topoisomerase I [Streptomyces globisporus].	22.00	591	343	21	2	530	13	547	5e-07	63.9
rs:WP_002660735	DNA topoisomerase I [Borrelia burgdorferi].	24.32	625	345	27	2	565	5	562	5e-07	63.9
rs:WP_039649491	MULTISPECIES: DNA topoisomerase I [Streptomyces].	22.52	595	335	22	2	530	13	547	5e-07	63.9
rs:WP_029547225	DNA topoisomerase I [Rhodococcus sp. BCP1].	22.41	589	344	22	2	530	17	552	5e-07	63.9
tr:A0A066WYU1_COLSU	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:KDN60579.1};	21.18	557	364	19	3	521	4	523	5e-07	63.5
rs:WP_030799698	DNA topoisomerase I [Streptomyces sp. NRRL F-3273].	21.57	598	339	20	2	530	13	549	5e-07	63.9
tr:D3XTG5_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.65	147	76	4	188	319	52	190	5e-07	60.8
rs:WP_014922671	DNA topoisomerase I [Arthrobacter sp. Rue61a].	21.58	584	366	21	2	538	10	548	5e-07	63.9
rs:WP_040283448	DNA topoisomerase I [Tessaracoccus sp. SIT6].	23.27	606	351	25	32	566	19	581	5e-07	63.9
rs:WP_004276466	DNA topoisomerase I [Campylobacter upsaliensis].	23.04	434	270	16	3	410	5	400	5e-07	63.5
rs:WP_002823480	DNA topoisomerase I [Campylobacter coli].	22.09	652	400	23	3	618	5	584	5e-07	63.5
tr:E1MAK9_9STRE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.32	370	222	16	283	629	3	337	5e-07	63.2
tr:A0A077MCJ1_9MICO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.70	595	331	25	2	530	5	542	5e-07	63.9
rs:WP_030342635	DNA topoisomerase I [Streptomyces sp. NRRL S-1022].	22.37	599	331	23	2	530	13	547	5e-07	63.9
tr:D3XTE1_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.65	147	76	4	188	319	54	192	5e-07	60.8
tr:A9X902_VIBPE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.61	196	104	6	163	343	31	209	5e-07	60.8
tr:L7JZB6_TRAHO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.34	419	263	19	1	394	1	390	5e-07	63.5
rs:WP_022423481	DNA topoisomerase [Clostridium sp. CAG:440].	33.99	153	94	4	433	579	43	194	5e-07	60.8
tr:D3XTG6_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.65	147	76	4	188	319	52	190	5e-07	60.8
rs:WP_029369302	DNA topoisomerase I [Mycobacterium sp. UM_WWY].	22.41	589	348	20	2	530	19	558	5e-07	63.9
rs:WP_032504065	DNA topoisomerase I [Propionibacterium acnes].	22.22	603	324	25	3	530	7	539	5e-07	63.9
rs:WP_030648197	MULTISPECIES: DNA topoisomerase I [Streptomyces].	21.90	589	345	21	2	530	13	546	5e-07	63.9
rs:WP_014557857	reverse gyrase [Fervidicoccus fontis].	25.57	438	252	21	88	481	761	1168	5e-07	63.9
rs:XP_003884247	putative DNA topoisomerase III alpha [Neospora caninum Liverpool].	27.59	145	94	1	188	321	208	352	5e-07	63.5
rs:WP_032815246	DNA topoisomerase I, partial [Bacteroides xylanisolvens].	28.99	138	89	5	549	684	18	148	5e-07	60.5
rs:WP_022890767	DNA topoisomerase I [Agromyces italicus].	22.54	639	379	21	2	571	6	597	5e-07	63.5
tr:K2A1G8_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	25.79	318	186	11	2	303	3	286	5e-07	62.0
tr:K0JTU7_SACES	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.06	594	335	24	2	530	42	578	5e-07	63.5
tr:C7IPE3_THEET	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.99	361	223	12	295	629	1	332	5e-07	62.8
rs:WP_039693979	hypothetical protein, partial [Streptococcus gallolyticus].	26.46	257	131	10	474	676	1	253	5e-07	62.8
rs:WP_036391367	DNA topoisomerase I [Mycobacterium farcinogenes].	22.66	587	349	22	2	530	15	554	5e-07	63.5
rs:WP_037921053	DNA topoisomerase I [Streptomyces sp. PCS3-D2].	22.52	595	334	23	2	530	13	546	5e-07	63.5
rs:XP_003671229	hypothetical protein NDAI_0G02110 [Naumovozyma dairenensis CBS 421].	23.31	472	278	18	3	401	4	464	5e-07	63.5
tr:S9V0P8_9TRYP	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EPY20486.1};	23.73	628	383	27	86	643	107	708	5e-07	63.5
rs:WP_000932886	DNA topoisomerase III [Bacillus thuringiensis].	32.46	114	65	4	3	108	7	116	5e-07	59.7
rs:WP_037319125	DNA topoisomerase I [Ruminobacter sp. RM87].	22.00	459	285	17	187	616	189	603	5e-07	63.5
rs:WP_002545594	DNA topoisomerase I [Propionibacterium acnes].	22.19	604	323	24	3	530	7	539	5e-07	63.5
rs:WP_047119826	DNA topoisomerase I [Arthrobacter sp. YC-RL1].	24.02	512	301	20	80	538	79	555	5e-07	63.5
rs:WP_032601606	hypothetical protein [Staphylococcus epidermidis].	33.90	118	69	3	500	615	14	124	5e-07	60.8
rs:WP_031184668	DNA topoisomerase I [Streptomyces sp. NRRL F-5635].	22.18	595	337	21	2	530	13	547	5e-07	63.5
rs:WP_030012191	DNA topoisomerase I [Streptomyces lavendulae].	22.35	595	335	23	2	530	13	546	5e-07	63.5
rs:WP_006634754	DNA topoisomerase I [Microcoleus vaginatus].	23.18	578	341	19	3	530	4	528	5e-07	63.5
rs:WP_017955760	DNA topoisomerase I [actinobacterium SCGC AAA023-J06].	22.43	593	336	24	1	530	9	540	5e-07	63.5
tr:A0A0A1G3I5_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.87	182	96	6	163	329	30	198	5e-07	60.8
rs:WP_031085642	DNA topoisomerase I [Streptomyces sp. NRRL S-1831].	22.18	595	337	21	2	530	13	547	5e-07	63.5
rs:XP_010786073	PREDICTED: DNA topoisomerase 3-alpha-like, partial [Notothenia coriiceps].	26.61	218	142	5	188	395	264	473	5e-07	63.2
rs:WP_021033792	DNA topoisomerase I [Campylobacter coli].	21.57	649	407	22	3	618	5	584	5e-07	63.5
rs:WP_015938306	DNA topoisomerase I [Arthrobacter chlorophenolicus].	21.94	588	363	21	2	538	10	552	5e-07	63.5
tr:W1YBT9_9ZZZZ	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ETJ39170.1}; Flags: Fragment;	54.10	61	22	2	161	215	3	63	5e-07	58.5
tr:A4Z8U5_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.65	147	76	4	188	319	57	195	5e-07	60.8
tr:D3XTF4_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.65	147	76	4	188	319	54	192	5e-07	60.8
rs:WP_032518605	DNA topoisomerase I [Prochlorococcus marinus].	24.77	331	206	11	260	572	269	574	5e-07	63.5
tr:F9MTF6_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	22.86	490	314	17	157	616	9	464	5e-07	63.2
rs:WP_005468581	DNA topoisomerase I [Porphyromonas catoniae].	23.03	534	344	17	1	521	1	480	5e-07	63.5
rs:WP_030404212	DNA topoisomerase I [Streptomyces sp. NRRL F-5555].	22.18	595	337	21	2	530	13	547	5e-07	63.5
rs:WP_023016601	MULTISPECIES: DNA topoisomerase I [Corynebacterium].	23.52	557	321	20	38	530	30	545	5e-07	63.5
tr:I1T8P3_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.91	158	79	5	187	329	59	204	5e-07	60.8
rs:WP_003882599	MULTISPECIES: DNA topoisomerase I [Mycobacterium].	22.66	587	349	22	2	530	15	554	5e-07	63.5
tr:S0DUX7_GIBF5	SubName: Full=Related to DNA topoisomerase III {ECO:0000313|EMBL:CCT66255.1};	21.16	567	350	19	3	520	4	522	6e-07	63.5
rs:WP_034740368	DNA topoisomerase I [Chryseobacterium vrystaatense].	22.97	418	232	12	3	392	5	360	6e-07	63.5
rs:WP_035344662	DNA topoisomerase I [Acholeplasma modicum].	23.30	661	382	30	2	622	4	579	6e-07	63.2
rs:WP_033219326	DNA topoisomerase I [Streptomyces virginiae].	22.18	595	336	22	2	530	13	546	6e-07	63.5
rs:WP_019527427	DNA topoisomerase I [Streptomyces sp. FxanaD5].	22.48	596	334	21	2	530	13	547	6e-07	63.5
tr:D3XTD8_VIBSP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.65	147	76	4	188	319	52	190	6e-07	60.8
rs:WP_043827116	DNA topoisomerase I [Amycolatopsis orientalis].	21.64	610	325	22	2	530	20	557	6e-07	63.5
rs:WP_037808332	DNA topoisomerase I [Streptomyces sp. NRRL F-3213].	21.64	610	325	22	2	530	20	557	6e-07	63.5
rs:WP_005723191	topoisomerase I [Lactobacillus crispatus].	24.74	489	291	21	3	443	5	464	6e-07	63.5
tr:A4Z8U4_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.65	147	76	4	188	319	52	190	6e-07	60.8
rs:WP_031115960	DNA topoisomerase I [Streptomyces sp. NRRL WC-3641].	22.32	596	335	22	2	530	13	547	6e-07	63.5
rs:WP_008625905	hypothetical protein, partial [Paraprevotella xylaniphila].	28.99	138	89	5	549	684	17	147	6e-07	60.1
rs:WP_000932885	DNA topoisomerase III [Bacillus cereus].	32.46	114	65	4	3	108	7	116	6e-07	59.7
rs:WP_028959465	DNA topoisomerase I [Streptomyces sp. UNC401CLCol].	22.48	596	334	21	2	530	13	547	6e-07	63.5
tr:S4PI25_9PORP	SubName: Full=DNA topoisomerase III, Bacteroidales-type {ECO:0000313|EMBL:GAD06917.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAD06917.1};	28.83	163	108	4	274	432	2	160	6e-07	61.2
rs:WP_023030006	DNA topoisomerase I [Corynebacterium sp. KPL1818].	23.52	557	321	20	38	530	30	545	6e-07	63.5
rs:WP_038848444	DNA topoisomerase I [Campylobacter coli].	21.57	649	407	22	3	618	5	584	6e-07	63.2
rs:XP_003852710	DNA topoisomerase 3 [Zymoseptoria tritici IPO323].	21.64	633	401	22	3	576	6	602	6e-07	63.2
rs:WP_021085359	DNA topoisomerase I [Campylobacter concisus].	23.00	661	409	25	3	629	4	598	6e-07	63.2
rs:WP_007390460	DNA topoisomerase I [Megasphaera sp. UPII 199-6].	22.34	591	379	21	82	630	109	661	6e-07	63.2
rs:WP_032526743	DNA topoisomerase I [Prochlorococcus marinus].	24.48	335	200	11	261	572	270	574	6e-07	63.5
rs:WP_046332923	hypothetical protein, partial [Lactobacillus kimbladii].	21.94	679	409	27	3	618	4	624	6e-07	63.2
tr:K0H470_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.65	147	76	4	188	319	61	199	6e-07	60.8
tr:X7ZZN7_MYCAV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.97	566	327	22	32	530	14	537	6e-07	63.5
rs:WP_030726803	DNA topoisomerase I [Streptomyces sp. NRRL S-237].	22.52	595	334	23	2	530	13	546	6e-07	63.5
rs:WP_011102734	DNA topoisomerase I [Tropheryma whipplei].	23.83	491	300	17	77	528	66	521	6e-07	63.5
rs:WP_030709415	DNA topoisomerase I [Streptomyces sp. NRRL F-2580].	22.18	595	336	22	2	530	13	546	6e-07	63.5
rs:WP_030846072	DNA topoisomerase I [Streptomyces sp. NRRL S-475].	21.90	589	346	21	2	530	13	547	6e-07	63.5
rs:WP_047252202	DNA topoisomerase I [Corynebacterium testudinoris].	24.37	513	285	20	80	530	79	550	6e-07	63.5
rs:WP_012085191	DNA topoisomerase I [Kineococcus radiotolerans].	22.70	630	381	23	2	571	17	600	6e-07	63.5
rs:WP_033596031	DNA topoisomerase III, partial [Enterococcus faecalis].	29.27	164	92	4	450	611	17	158	6e-07	61.2
rs:WP_029290883	DNA topoisomerase I [Cellulomonas sp. HZM].	22.33	618	375	22	2	560	4	575	6e-07	63.5
rs:WP_013607780	DNA topoisomerase I [Sphaerochaeta globosa].	22.72	405	248	10	168	533	144	522	6e-07	63.2
rs:WP_026862435	DNA topoisomerase I [Intrasporangiaceae bacterium URHB0013].	22.34	591	343	21	2	530	8	544	6e-07	63.5
rs:WP_001875692	topA [Helicobacter pylori].	24.07	324	217	9	99	399	77	394	7e-07	63.2
rs:WP_038814824	DNA topoisomerase I [Campylobacter jejuni].	21.78	652	402	23	3	618	5	584	7e-07	63.2
rs:WP_005721409	topoisomerase I [Lactobacillus crispatus].	24.03	491	292	22	3	443	5	464	7e-07	63.2
rs:WP_025778061	DNA topoisomerase I [Brevibacterium sp. VCM10].	22.41	598	348	23	2	538	10	552	7e-07	63.2
tr:A0A0D3A2X7_BRAOL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Bo1g011520.1};	24.09	440	254	18	32	413	391	808	7e-07	63.5
rs:WP_018547966	DNA topoisomerase I [Streptomyces sp. LaPpAH-108].	23.29	584	344	23	2	530	13	547	7e-07	63.2
rs:WP_030957759	DNA topoisomerase I [Streptomyces sp. NRRL S-378].	21.98	596	336	22	2	530	13	546	7e-07	63.2
tr:A0A093ZR94_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY13575.1};	23.88	381	255	15	35	394	74	440	7e-07	63.2
rs:WP_005280920	DNA topoisomerase I [Corynebacterium accolens].	23.52	557	321	20	38	530	30	545	7e-07	63.2
rs:WP_040999438	DNA topoisomerase I [Chryseobacterium oranimense].	22.93	410	242	11	3	392	5	360	7e-07	63.2
rs:WP_042771766	hypothetical protein [Streptococcus sp. HSISS3].	37.65	85	52	1	41	124	4	88	7e-07	59.3
tr:B5GPN9_STRC2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.61	398	229	12	185	530	166	536	7e-07	63.2
rs:WP_023028183	DNA topoisomerase I [Corynebacterium sp. KPL1824].	23.52	557	321	20	38	530	30	545	7e-07	63.2
rs:WP_027466409	DNA topoisomerase I [Curtobacterium sp. UNCCL17].	22.95	597	335	23	2	528	6	547	7e-07	63.2
rs:WP_042667859	DNA topoisomerase [Desulfurococcus amylolyticus].	21.79	514	330	18	90	580	731	1195	7e-07	63.5
tr:A0A063BQ72_9HYPO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KDB11172.1};	20.64	344	229	12	3	314	4	335	7e-07	63.2
rs:WP_004367877	DNA topoisomerase TopB, partial [Prevotella nigrescens].	31.36	118	64	4	4	110	5	116	7e-07	59.3
rs:WP_014408458	DNA topoisomerase I [Rickettsia rhipicephali].	22.71	687	413	29	1	629	1	627	7e-07	63.2
tr:A0A086KE27_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.89	426	279	14	187	585	124	518	7e-07	62.8
rs:WP_031147671	DNA topoisomerase I [Streptomyces erythrochromogenes].	21.98	596	336	22	2	530	13	546	7e-07	63.2
rs:WP_045808600	DNA topoisomerase I [Candidatus Neoehrlichia lotoris].	22.85	687	413	33	1	629	1	628	7e-07	63.2
tr:X6P1T3_RETFI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.86	420	259	16	138	533	19	397	7e-07	62.4
tr:W7YCM7_9BACT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAF05223.1};	30.54	167	96	7	528	676	1	165	7e-07	61.2
rs:WP_039382418	DNA topoisomerase I [Mycobacterium setense].	22.66	587	349	22	2	530	15	554	7e-07	63.2
rs:WP_013021919	DNA topoisomerase I [Mycoplasma agalactiae].	21.36	632	402	25	38	642	24	587	7e-07	62.8
rs:WP_035163807	topoisomerase I [Lactobacillus crispatus].	24.74	489	291	21	3	443	5	464	7e-07	63.2
rs:WP_007451903	DNA topoisomerase I [Streptomyces coelicoflavus].	22.02	595	338	21	2	530	13	547	8e-07	63.2
rs:WP_023034502	DNA topoisomerase I [Propionibacterium sp. KPL1844].	21.90	621	370	21	3	560	7	575	8e-07	63.2
rs:WP_015130898	DNA topoisomerase I [Calothrix sp. PCC 7507].	21.04	347	240	8	240	574	257	581	8e-07	63.2
rs:WP_037760867	DNA topoisomerase I [Streptomyces olindensis].	22.32	596	335	22	2	530	13	547	8e-07	63.2
rs:WP_021105143	DNA topoisomerase I [Propionibacterium granulosum].	21.90	621	370	21	3	560	7	575	8e-07	63.2
rs:WP_018777017	MULTISPECIES: DNA topoisomerase I [Arthrobacter].	21.40	584	367	22	2	538	10	548	8e-07	63.2
rs:WP_041782277	DNA topoisomerase I [Mycobacterium chubuense].	22.30	592	345	22	2	530	40	579	8e-07	63.2
rs:WP_030755950	MULTISPECIES: DNA topoisomerase I [Streptomyces].	22.15	596	335	23	2	530	13	546	8e-07	63.2
rs:WP_039355843	DNA topoisomerase I [Candidatus Protochlamydia amoebophila].	24.18	488	294	20	92	534	69	525	8e-07	63.2
rs:WP_011731723	DNA topoisomerase I [Campylobacter fetus].	22.78	654	387	29	2	614	3	579	8e-07	62.8
rs:WP_042507044	DNA topoisomerase I [Tropheryma whipplei].	24.19	492	297	18	77	528	66	521	8e-07	63.2
rs:WP_008598832	MULTISPECIES: DNA topoisomerase I [Propionibacterium].	22.87	586	341	23	3	530	7	539	8e-07	63.2
rs:WP_042506202	DNA topoisomerase I [Tropheryma whipplei].	24.19	492	297	18	77	528	66	521	8e-07	63.2
rs:XP_008466640	PREDICTED: uncharacterized protein LOC103503996, partial [Cucumis melo].	26.24	263	161	9	64	303	333	585	8e-07	62.8
rs:WP_018017365	DNA topoisomerase I [Corynebacterium capitovis].	23.79	559	310	24	36	530	25	531	8e-07	63.2
tr:Q4SVN5_TETNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.26	155	85	5	251	395	222	366	8e-07	63.2
tr:T1BLX4_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EQD73981.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EQD73981.1}; Flags: Fragment;	22.17	433	259	19	244	639	35	426	8e-07	62.8
rs:WP_038110921	DNA topoisomerase I [Tropheryma whipplei].	24.19	492	297	18	77	528	66	521	8e-07	63.2
rs:WP_004810389	DNA topoisomerase I [Propionibacterium avidum].	22.42	611	313	27	3	530	7	539	8e-07	63.2
rs:WP_042745307	hypothetical protein [Oenococcus oeni].	28.27	191	114	6	200	375	1	183	8e-07	60.5
tr:J7RTA4_KAZNA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.85	348	214	11	253	574	297	619	8e-07	62.8
tr:K2EQB9_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	23.37	398	256	13	88	445	42	430	8e-07	62.4
rs:WP_030426319	DNA topoisomerase I, partial [Acinetobacter baumannii].	30.49	164	93	4	273	426	79	231	8e-07	60.5
rs:WP_045320820	DNA topoisomerase I [Streptomyces sp. NRRL F-4428].	21.98	596	336	22	2	530	13	546	8e-07	63.2
rs:WP_030029965	DNA topoisomerase I [Streptomyces flavotricini].	21.98	596	336	22	2	530	13	546	8e-07	63.2
tr:A0A094SR49_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KGA21208.1};	22.24	598	321	22	2	528	12	536	9e-07	63.2
tr:A9YJ44_DROME	SubName: Full=CG3458 {ECO:0000313|EMBL:ADG51438.1}; SubName: Full=Topoisomerase 3 beta {ECO:0000313|EMBL:ABW92696.1}; Flags: Fragment;	23.90	205	131	5	357	557	45	228	9e-07	60.8
rs:WP_030422570	DNA topoisomerase I [Streptomyces sp. NRRL F-5065].	22.20	590	343	21	2	530	13	547	9e-07	63.2
rs:WP_002517381	DNA topoisomerase I [Propionibacterium acnes].	22.87	586	341	23	3	530	7	539	9e-07	62.8
rs:WP_014598755	DNA topoisomerase I [Propionibacterium acnes].	22.87	586	341	23	3	530	7	539	9e-07	62.8
rs:WP_039325786	DNA topoisomerase I [Mycobacterium setense].	22.66	587	349	22	2	530	15	554	9e-07	62.8
rs:WP_038104331	DNA topoisomerase I [Tropheryma whipplei].	24.19	492	297	18	77	528	66	521	9e-07	62.8
rs:WP_013438823	hypothetical protein, partial [Edwardsiella tarda].	31.72	145	93	4	522	664	2	142	9e-07	59.7
tr:M3JWC9_CANMX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EMG47260.1};	21.43	644	393	25	3	582	4	598	9e-07	62.8
rs:WP_002530121	DNA topoisomerase I [Propionibacterium acnes].	22.87	586	341	23	3	530	7	539	9e-07	62.8
rs:WP_002524667	DNA topoisomerase I [Propionibacterium acnes].	22.87	586	341	23	3	530	7	539	9e-07	62.8
rs:WP_005276527	DNA topoisomerase I [Corynebacterium accolens].	23.52	557	321	20	38	530	30	545	9e-07	62.8
rs:WP_034672551	DNA topoisomerase I [Chryseobacterium formosense].	24.87	398	249	13	3	392	5	360	9e-07	62.8
rs:WP_020955187	DNA topoisomerase I [Borrelia miyamotoi].	22.87	647	371	27	2	587	5	584	9e-07	62.8
rs:WP_002529762	MULTISPECIES: DNA topoisomerase I [Propionibacterium].	22.87	586	341	23	3	530	7	539	9e-07	62.8
rs:WP_023487490	DNA topoisomerase I [Propionibacterium acnes].	22.87	586	341	23	3	530	7	539	9e-07	62.8
tr:D3XTE0_VIBSP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.65	147	76	4	188	319	52	190	9e-07	60.1
rs:WP_014540818	DNA topoisomerase I [Borrelia burgdorferi].	24.56	623	346	27	2	565	5	562	9e-07	62.8
rs:WP_002539778	DNA topoisomerase I [Propionibacterium acnes].	22.87	586	341	23	3	530	7	539	9e-07	62.8
tr:X1J8G7_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S21362 {ECO:0000313|EMBL:GAH77810.1}; Flags: Fragment;	28.57	189	125	4	157	338	40	225	9e-07	60.5
rs:WP_041129894	DNA topoisomerase I [Streptomyces vietnamensis].	22.00	591	343	21	2	530	13	547	9e-07	62.8
rs:WP_035433370	topoisomerase, partial [Lactobacillus fermentum].	25.78	353	204	15	3	319	4	334	9e-07	62.8
rs:WP_005327151	DNA topoisomerase I [Corynebacterium tuberculostearicum].	24.60	557	316	23	38	530	30	546	9e-07	62.8
tr:I1T8N8_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	29.70	165	101	3	187	344	59	215	9e-07	60.1
rs:WP_006142055	DNA topoisomerase I [Streptomyces griseoaurantiacus].	21.62	592	344	18	2	530	13	547	9e-07	62.8
rs:WP_042908466	DNA topoisomerase I [Mycobacterium avium].	22.88	590	343	22	2	530	19	557	9e-07	62.8
rs:WP_043221100	DNA topoisomerase I [Streptomyces sp. NRRL F-5193].	22.41	598	332	22	2	530	13	547	9e-07	62.8
rs:XP_011107696	hypothetical protein H072_1705 [Dactylellina haptotyla CBS 200.50].	22.52	493	292	18	82	531	38	483	1e-06	62.4
tr:K1TSP6_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC62381.1}; Flags: Fragment;	33.65	104	68	1	263	365	3	106	1e-06	59.3
rs:WP_040634296	DNA topoisomerase I [Mycobacterium phlei].	21.94	597	341	21	2	530	16	555	1e-06	62.8
rs:WP_030184011	DNA topoisomerase I [Streptomyces violaceorubidus].	21.24	612	339	20	2	530	13	564	1e-06	62.8
tr:S7WCX6_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.71	425	279	14	188	585	208	601	1e-06	62.8
rs:WP_018694136	hypothetical protein [Algicola sagamiensis].	21.61	657	396	25	1	621	1	574	1e-06	62.8
tr:I1T8N9_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	29.70	165	101	3	187	344	59	215	1e-06	60.1
tr:B9VRR5_9BACT	SubName: Full=TopR {ECO:0000313|EMBL:ACM09964.1}; Flags: Fragment;	32.19	146	83	3	168	312	7	137	1e-06	59.3
tr:A0A086KLT8_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.89	426	279	14	187	585	207	601	1e-06	62.8
tr:M5Z1D3_HELPX	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EMJ45343.1};	27.20	239	148	6	99	317	77	309	1e-06	61.6
rs:WP_002525218	MULTISPECIES: DNA topoisomerase I [Propionibacterium].	22.87	586	341	23	3	530	7	539	1e-06	62.8
rs:WP_025755476	DNA topoisomerase I [Mycoplasma cricetuli].	24.82	423	274	15	39	439	26	426	1e-06	62.4
rs:WP_014172429	DNA topoisomerase I [Propionibacterium acnes].	22.87	586	341	23	3	530	7	539	1e-06	62.8
rs:WP_002534294	DNA topoisomerase I [Propionibacterium acnes].	22.87	586	341	23	3	530	7	539	1e-06	62.8
tr:A4Z8V2_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.65	147	76	4	188	319	56	194	1e-06	60.1
tr:Q7V627_PROMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.44	459	284	14	157	572	162	591	1e-06	62.8
tr:K1ZHR3_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.49	684	429	23	1	641	1	619	1e-06	62.8
rs:WP_000513605	hypothetical protein, partial [Escherichia coli].	26.61	342	209	16	73	389	74	398	1e-06	62.0
rs:WP_044068334	DNA topoisomerase I [Propionibacterium acnes].	22.87	586	341	23	3	530	7	539	1e-06	62.8
rs:WP_002785538	DNA topoisomerase I [Campylobacter coli].	21.73	649	406	22	3	618	5	584	1e-06	62.4
tr:L2JGS7_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELA79744.1};	31.18	170	112	4	3	168	5	173	1e-06	59.3
rs:WP_038452680	DNA topoisomerase I [Campylobacter fetus].	22.78	654	387	29	2	614	3	579	1e-06	62.4
rs:WP_023031440	DNA topoisomerase I [Propionibacterium sp. KPL2008].	22.87	586	341	23	3	530	7	539	1e-06	62.8
rs:WP_011096652	DNA topoisomerase I [Tropheryma whipplei].	23.83	491	300	17	77	528	66	521	1e-06	62.8
rs:WP_044006975	DNA topoisomerase I [Borrelia valaisiana].	22.83	657	384	26	2	599	5	597	1e-06	62.8
tr:A0A086QKJ5_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.71	425	279	14	188	585	208	601	1e-06	62.8
rs:WP_023862894	DNA topoisomerase I [Mycobacterium avium].	22.88	590	343	22	2	530	19	557	1e-06	62.8
rs:WP_020567233	hypothetical protein [Lewinella persica].	23.69	401	257	10	3	392	5	367	1e-06	62.8
rs:WP_007270845	DNA topoisomerase I [Arthrobacter gangotriensis].	22.79	588	346	23	1	530	11	548	1e-06	62.8
rs:WP_041369758	DNA topoisomerase I, partial [Nakamurella multipartita].	22.62	641	366	24	1	571	14	594	1e-06	62.8
rs:WP_016460876	DNA topoisomerase I [Actinomyces sp. HPA0247].	23.50	634	371	24	2	571	5	588	1e-06	62.8
rs:WP_039329840	hypothetical protein [Myroides sp. A21].	22.43	749	441	30	1	687	1	671	1e-06	62.4
rs:XP_008466289	PREDICTED: uncharacterized protein LOC103503742 [Cucumis melo].	23.11	463	300	17	64	480	46	498	1e-06	62.8
rs:WP_002350038	toprim domain protein, partial [Enterococcus faecium].	32.41	145	85	4	3	139	5	144	1e-06	59.3
tr:I0RRM7_MYCPH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.94	597	341	21	2	530	3	542	1e-06	62.8
rs:WP_042958446	membrane protein [Enterococcus faecium].	39.81	103	58	1	103	201	3	105	1e-06	59.3
rs:WP_018568916	DNA topoisomerase I [Streptomyces sp. PsTaAH-124].	22.02	595	338	21	2	530	13	547	1e-06	62.8
rs:WP_037894231	DNA topoisomerase I [Streptomyces sp. Tu 6176].	22.02	595	338	21	2	530	13	547	1e-06	62.8
tr:D3XTG4_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.65	147	76	4	188	319	54	192	1e-06	59.7
tr:A9X919_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.65	147	76	4	188	319	54	192	1e-06	59.7
rs:WP_044822296	DNA topoisomerase I, partial [Bacillus thuringiensis].	25.32	308	202	11	105	392	82	381	1e-06	61.6
rs:WP_002945497	DNA topoisomerase I [Campylobacter rectus].	21.90	653	400	27	3	618	4	583	1e-06	62.4
rs:WP_042849901	DNA topoisomerase I [Prochlorococcus sp. MIT 0604].	24.32	333	203	10	261	572	270	574	1e-06	62.4
tr:C8X984_NAKMY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.62	641	366	24	1	571	14	594	1e-06	62.8
tr:A0A086L562_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.94	425	278	14	188	585	208	601	1e-06	62.4
rs:WP_016666857	DNA topoisomerase I [Propionibacterium sp. HGH0353].	22.42	611	313	27	3	530	7	539	1e-06	62.8
tr:A6D7J0_9VIBR	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EDL51415.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EDL51415.1};	23.65	296	178	8	359	633	23	291	1e-06	61.2
gpu:CP011497_3232	DNA topoisomerase I [Streptomyces incarnatus]	22.18	595	337	21	2	530	13	547	1e-06	62.8
rs:WP_028421010	DNA topoisomerase I [Streptomyces sp. GXT6].	21.51	595	341	20	2	530	13	547	1e-06	62.8
rs:WP_000277565	DNA topoisomerase I [Helicobacter pylori].	22.65	468	310	11	99	537	77	521	1e-06	62.4
rs:WP_032839579	DNA topoisomerase I, partial [Gardnerella vaginalis].	25.93	324	186	12	271	571	4	296	1e-06	61.6
rs:WP_031336600	hypothetical protein [Xylella fastidiosa].	51.67	60	25	1	168	223	30	89	1e-06	58.5
rs:WP_033647056	hypothetical protein [Enterococcus faecium].	30.33	122	82	2	479	597	1	122	1e-06	58.9
rs:WP_021668772	hypothetical protein, partial [Prevotella disiens].	27.38	168	112	4	347	507	23	187	1e-06	59.3
rs:WP_018172633	DNA topoisomerase I [Microbacterium sp. 292MF].	24.58	301	183	8	257	538	272	547	1e-06	62.4
rs:WP_017888707	hypothetical protein [Curtobacterium flaccumfaciens].	22.61	597	337	23	2	528	6	547	1e-06	62.4
tr:E7BUB0_VIBCL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.88	146	75	5	187	317	47	184	1e-06	59.7
rs:WP_020760618	DNA topoisomerase, partial [Gardnerella vaginalis].	26.35	334	172	13	271	571	2	294	1e-06	61.6
rs:WP_041344248	DNA topoisomerase I [Mycobacterium avium].	22.15	596	340	22	2	530	19	557	1e-06	62.4
rs:WP_033857306	hypothetical protein, partial [Acinetobacter baumannii].	35.90	78	50	0	453	530	22	99	1e-06	58.5
tr:R8NCA0_BACCE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOP43912.1};	30.61	147	93	4	543	682	5	149	1e-06	59.3
rs:WP_009369974	DNA topoisomerase I [Megasphaera genomosp. type_1].	22.64	592	376	22	82	630	109	661	1e-06	62.4
rs:WP_032521294	DNA topoisomerase I [Prochlorococcus marinus].	22.12	330	217	8	258	572	270	574	1e-06	62.4
rs:WP_019684867	DNA topoisomerase I [Mycobacterium avium].	22.88	590	343	22	2	530	19	557	1e-06	62.4
rs:XP_004896708	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Heterocephalus glaber].	22.27	494	285	17	188	619	239	695	1e-06	62.4
rs:WP_020272722	DNA topoisomerase 1 [Streptomyces afghaniensis].	22.32	596	335	22	2	530	13	547	1e-06	62.4
rs:XP_012076277	PREDICTED: uncharacterized protein LOC105637432 [Jatropha curcas].	24.22	384	243	14	64	414	371	739	1e-06	62.4
tr:W7BP32_9LIST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	24.77	323	217	9	105	408	82	397	1e-06	62.0
tr:A0A086QAR6_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.94	425	278	14	188	585	208	601	1e-06	62.4
rs:WP_002518689	DNA topoisomerase I [Propionibacterium acnes].	22.87	586	341	23	3	530	7	539	1e-06	62.4
tr:V5UUT1_9VIBR	SubName: Full=Topoisomerase I {ECO:0000313|EMBL:AHB81951.1}; Flags: Fragment;	33.57	140	70	4	188	312	9	140	1e-06	58.9
rs:WP_004928211	DNA topoisomerase I [Streptomyces griseoflavus].	22.02	595	338	21	2	530	13	547	1e-06	62.4
rs:WP_028728976	hypothetical protein, partial [Parabacteroides gordonii].	28.22	163	106	6	517	676	2	156	1e-06	59.3
rs:WP_041315862	DNA topoisomerase I, partial [Saccharothrix espanaensis].	22.93	593	335	24	3	530	1	536	1e-06	62.4
rs:WP_002803036	DNA topoisomerase I [Campylobacter coli].	21.78	652	402	23	3	618	5	584	1e-06	62.4
tr:A0A0A8LDJ3_9SACH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.52	385	256	9	188	543	220	583	1e-06	62.0
rs:WP_006068704	DNA topoisomerase I [Borrelia valaisiana].	22.60	655	388	25	2	599	5	597	1e-06	62.4
tr:A0A091BWR9_9ENTE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KFN90076.1}; EC=5.99.1.- {ECO:0000313|EMBL:KFN90076.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KFN90076.1};	32.43	111	70	2	501	611	9	114	1e-06	59.3
tr:E2ZN60_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	42.86	77	41	1	241	317	44	117	1e-06	58.5
rs:WP_001899687	DNA topoisomerase I [Helicobacter pylori].	22.06	467	314	11	99	537	77	521	1e-06	62.0
rs:WP_000277568	DNA topoisomerase I [Helicobacter pylori].	22.65	468	310	11	99	537	77	521	1e-06	62.0
rs:WP_042538864	DNA topoisomerase I [Curtobacterium flaccumfaciens].	22.28	597	339	22	2	528	6	547	1e-06	62.4
tr:I4BQ92_MYCCN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.30	592	345	22	2	530	27	566	1e-06	62.4
tr:A0A0A1G3J4_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.58	137	84	2	188	317	51	187	1e-06	59.7
rs:WP_026541356	DNA topoisomerase I [Arthrobacter nicotinovorans].	21.75	584	365	21	2	538	10	548	1e-06	62.4
tr:A4Z8V1_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.65	147	76	4	188	319	57	195	1e-06	59.7
rs:WP_019776059	hypothetical protein, partial [Streptococcus sobrinus].	30.25	162	92	4	235	382	20	174	1e-06	58.9
rs:WP_015140585	DNA topoisomerase I [Nostoc sp. PCC 7524].	21.40	514	339	15	90	565	80	566	1e-06	62.4
tr:D3XTE6_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.65	147	76	4	188	319	57	195	1e-06	59.7
tr:T2SB35_HELPX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.12	642	404	23	3	614	4	579	1e-06	62.0
tr:A9X8V8_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	29.88	164	100	3	188	344	50	205	1e-06	59.3
rs:WP_009056800	DNA topoisomerase I [Atopobium sp. ICM58].	23.19	634	373	27	2	571	5	588	1e-06	62.4
rs:WP_014674049	DNA topoisomerase I [Streptomyces hygroscopicus].	22.18	595	337	21	2	530	13	547	1e-06	62.4
tr:V5UW76_SALCS	SubName: Full=Topoisomerase I {ECO:0000313|EMBL:AHB81945.1}; Flags: Fragment;	32.39	142	73	4	186	312	7	140	1e-06	58.9
rs:WP_035147818	DNA topoisomerase I [Campylobacter fetus].	22.78	654	387	29	2	614	3	579	1e-06	62.0
rs:WP_032587892	DNA topoisomerase I, partial [Bacteroides fragilis].	29.88	164	102	8	517	676	1	155	1e-06	58.9
rs:WP_040665938	DNA topoisomerase I, partial [Nitrolancea hollandica].	22.84	416	259	13	156	533	42	433	1e-06	61.6
rs:WP_029719788	DNA topoisomerase I [Saccharopolyspora rectivirgula].	22.84	591	339	22	2	530	29	564	1e-06	62.4
rs:WP_029812658	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	33.33	87	58	0	495	581	1	87	1e-06	58.5
tr:A0A023GJT5_9ACAR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.61	415	272	17	3	382	5	409	1e-06	61.6
rs:WP_034727019	DNA topoisomerase I [Chryseobacterium sp. JM1].	22.97	418	232	12	3	392	5	360	1e-06	62.0
tr:A4Z8V0_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.65	147	76	4	188	319	57	195	1e-06	59.7
tr:A9X8Z4_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.58	137	84	2	188	317	52	188	1e-06	59.3
rs:WP_030259285	MULTISPECIES: DNA topoisomerase I [Streptomyces].	22.04	599	336	23	2	530	12	549	1e-06	62.4
tr:I7IG82_VIBCL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	34.23	149	81	5	188	324	33	176	1e-06	59.3
rs:WP_019009533	DNA topoisomerase I [Deinococcus aquatilis].	23.21	586	338	25	3	530	10	541	1e-06	62.4
tr:X8B6F9_MYCAV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.22	594	338	22	4	530	1	537	1e-06	62.0
rs:WP_034755283	DNA topoisomerase I [Chryseobacterium sp. OV259].	23.44	418	230	12	3	392	5	360	1e-06	62.0
rs:WP_029146385	DNA topoisomerase I [Microbacterium luticocti].	23.74	497	280	19	90	530	82	535	1e-06	62.0
rs:WP_046777872	DNA topoisomerase I [Streptomyces sp. fd2-tb].	21.98	596	336	22	2	530	13	546	2e-06	62.0
rs:WP_031103564	DNA topoisomerase I [Streptomyces sp. NRRL S-146].	21.73	589	347	21	2	530	13	547	2e-06	62.0
tr:W5ACB0_WHEAT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.32	296	184	10	64	335	310	589	2e-06	62.0
rs:WP_035759241	DNA topoisomerase I [Granulicoccus phenolivorans].	22.41	656	390	23	19	591	10	629	2e-06	62.0
rs:WP_031482602	DNA topoisomerase I [Streptomyces bicolor].	22.22	594	338	22	2	530	13	547	2e-06	62.0
rs:WP_034692419	DNA topoisomerase I [Chryseobacterium sp. CF365].	23.36	578	322	19	3	540	5	501	2e-06	62.0
rs:WP_039369837	DNA topoisomerase I [Chryseobacterium taiwanense].	23.44	418	230	12	3	392	5	360	2e-06	62.0
tr:A9X8X7_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.81	172	88	5	187	343	56	211	2e-06	59.3
rs:WP_007491977	DNA topoisomerase I [Streptomyces zinciresistens].	22.28	597	334	23	2	530	13	547	2e-06	62.0
rs:WP_021087516	DNA topoisomerase I [Campylobacter concisus].	23.00	661	409	25	3	629	4	598	2e-06	62.0
tr:C0B3Z3_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.74	167	91	5	187	344	98	250	2e-06	60.1
tr:X2NB55_SALEN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.48	158	105	6	299	452	6	159	2e-06	58.9
rs:WP_042747138	hypothetical protein [Staphylococcus aureus].	22.20	581	350	23	65	590	97	630	2e-06	62.0
rs:WP_011731080	DNA topoisomerase I [Mycobacterium smegmatis].	22.92	589	345	24	2	530	16	555	2e-06	62.0
rs:WP_014306395	DNA topoisomerase I [Corynebacterium diphtheriae].	23.99	496	302	18	80	530	77	542	2e-06	62.0
rs:WP_018021499	DNA topoisomerase I [Corynebacterium doosanense].	23.91	506	299	19	77	530	75	546	2e-06	62.0
tr:A9X8V5_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.10	164	98	3	188	344	50	205	2e-06	59.3
rs:WP_029152330	DNA topoisomerase I [Microbacterium gubbeenense].	22.75	510	316	17	77	538	68	547	2e-06	62.0
rs:WP_034701543	DNA topoisomerase I [Chryseobacterium luteum].	22.97	418	232	12	3	392	5	360	2e-06	62.0
rs:WP_042820708	DNA topoisomerase I [Streptomyces sp. RSD-27].	22.05	594	338	21	2	530	13	546	2e-06	62.0
rs:WP_033792976	DNA topoisomerase I, partial [Helicobacter pylori].	27.34	256	159	8	82	317	61	309	2e-06	61.2
rs:WP_006256097	DNA topoisomerase III [Alloprevotella tannerae].	30.77	117	64	4	4	109	5	115	2e-06	58.2
gpu:LN831790_3259	DNA topoisomerase 1 [Streptomyces leeuwenhoekii]	21.81	596	338	20	2	530	13	547	2e-06	62.0
rs:WP_030323404	DNA topoisomerase I [Streptomyces flavochromogenes].	21.53	590	347	20	2	530	13	547	2e-06	62.0
rs:WP_002826940	DNA topoisomerase I [Campylobacter coli].	21.26	649	409	22	3	618	5	584	2e-06	61.6
rs:WP_006001245	MULTISPECIES: topoisomerase [Clostridiales].	35.87	92	59	0	497	588	16	107	2e-06	58.2
tr:A0A093VE97_PENMA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	21.47	354	218	11	188	528	112	418	2e-06	61.2
tr:F2RAB3_STRVP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.00	591	343	21	2	530	49	583	2e-06	62.0
rs:WP_030526578	DNA topoisomerase I [Phycicoccus jejuensis].	22.89	581	349	22	2	530	6	539	2e-06	62.0
tr:B9VRM4_9BACT	SubName: Full=TopR {ECO:0000313|EMBL:ACM09923.1}; Flags: Fragment;	33.12	154	82	5	163	312	3	139	2e-06	58.5
tr:A0A084QFC0_9HYPO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFA62655.1};	21.21	561	357	18	3	520	33	551	2e-06	61.6
rs:WP_002842632	DNA topoisomerase I [Campylobacter coli].	21.42	649	408	22	3	618	5	584	2e-06	61.6
rs:WP_024759186	DNA topoisomerase I [Streptomyces exfoliatus].	24.28	276	165	9	273	530	298	547	2e-06	62.0
tr:B7XDD8_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.03	153	91	5	188	332	45	192	2e-06	58.9
rs:WP_002538592	DNA topoisomerase I [Propionibacterium acnes].	22.87	586	341	23	3	530	7	539	2e-06	62.0
rs:WP_022898250	DNA topoisomerase I, partial [Corynebacterium-like bacterium B27].	23.61	305	182	8	252	530	38	317	2e-06	61.6
rs:WP_037968522	DNA topoisomerase I [Streptomyces sp. SS].	24.28	276	165	9	273	530	298	547	2e-06	62.0
rs:WP_030088839	DNA topoisomerase I, partial [Streptomyces decoyicus].	23.63	457	259	16	2	406	14	432	2e-06	61.2
tr:X1NF35_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S13387 {ECO:0000313|EMBL:GAI42632.1}; Flags: Fragment;	26.69	266	136	11	293	533	1	232	2e-06	59.7
rs:WP_019181621	DNA topoisomerase I [Microbacterium yannicii].	22.26	301	190	7	257	538	276	551	2e-06	62.0
rs:WP_029842021	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	33.33	87	58	0	495	581	1	87	2e-06	58.2
tr:D3XTG3_VIBSP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.41	171	88	5	188	343	52	206	2e-06	58.9
tr:W4S9F2_9XANT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.41	299	191	9	258	538	4	282	2e-06	61.6
rs:WP_041385137	DNA topoisomerase I [Prochlorococcus marinus].	22.44	459	284	14	157	572	145	574	2e-06	62.0
rs:WP_016636986	DNA topoisomerase I, partial [Gardnerella vaginalis].	23.43	431	262	15	187	571	143	551	2e-06	62.0
rs:WP_033776183	DNA topoisomerase I, partial [Helicobacter pylori].	27.62	239	147	7	99	317	77	309	2e-06	61.2
rs:WP_002911147	DNA topoisomerase I [Campylobacter jejuni].	21.42	649	408	22	3	618	5	584	2e-06	61.6
rs:WP_042687066	hypothetical protein [Candidatus Glomeribacter gigasporarum].	33.33	105	69	1	467	570	31	135	2e-06	58.5
rs:WP_004278075	DNA topoisomerase I [Campylobacter upsaliensis].	22.86	420	260	16	3	396	5	386	2e-06	61.6
tr:A0A0D6LKH7_9BILA	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EPB72560.1};	22.38	563	347	19	88	592	139	669	2e-06	61.6
rs:WP_002517152	DNA topoisomerase I [Propionibacterium acnes].	22.87	586	341	23	3	530	7	539	2e-06	61.6
tr:U5HC52_USTV1	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDE04881.1, ECO:0000313|EnsemblFungi:MVLG_04740T0};	21.13	653	405	27	3	598	5	604	2e-06	62.0
tr:I3VLZ1_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.33	166	100	6	188	344	60	220	2e-06	58.9
rs:WP_005729394	topoisomerase I [Lactobacillus crispatus].	24.95	489	290	22	3	443	5	464	2e-06	61.6
rs:WP_011174621	DNA topoisomerase I [Candidatus Protochlamydia amoebophila].	23.77	488	296	19	92	534	69	525	2e-06	61.6
rs:XP_007308131	prokaryotic type I DNA topoisomerase [Stereum hirsutum FP-91666 SS1].	21.21	660	427	24	3	608	4	624	2e-06	61.6
rs:WP_015171261	DNA topoisomerase I [Geitlerinema sp. PCC 7407].	22.72	383	230	10	187	530	173	528	2e-06	61.6
rs:WP_030925183	DNA topoisomerase I [Streptomyces sp. NRRL B-24720].	21.33	600	338	22	2	530	13	549	2e-06	61.6
tr:F3KGB5_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.62	381	193	16	291	629	1	325	2e-06	61.2
rs:WP_041993585	DNA topoisomerase I, partial [Capnocytophaga cynodegmi].	28.66	164	104	6	517	676	2	156	2e-06	58.5
rs:WP_038430708	DNA topoisomerase I [Mycobacterium avium].	22.32	596	339	22	2	530	19	557	2e-06	61.6
rs:WP_042281596	DNA topoisomerase I [Candidatus Protochlamydia sp. R18].	23.77	488	296	19	92	534	69	525	2e-06	61.6
rs:WP_002366149	toprim domain protein, partial [Enterococcus faecium].	31.47	143	85	4	3	137	4	141	2e-06	58.2
rs:WP_046830945	DNA topoisomerase I [Xanthomonas axonopodis].	21.67	563	362	18	100	631	75	589	2e-06	61.6
rs:WP_007516566	DNA topoisomerase I [Frankia sp. CN3].	22.80	649	357	26	2	571	63	646	2e-06	61.6
rs:XP_005834413	hypothetical protein GUITHDRAFT_50898, partial [Guillardia theta CCMP2712].	26.85	257	155	9	163	393	177	426	2e-06	61.2
rs:WP_033202856	DNA topoisomerase I [Streptomyces wedmorensis].	24.28	276	165	9	273	530	298	547	2e-06	61.6
rs:WP_018520405	MULTISPECIES: DNA topoisomerase I [Streptomyces].	21.83	600	335	22	2	530	13	549	2e-06	61.6
rs:WP_038851041	DNA topoisomerase I [Campylobacter coli].	21.42	649	408	22	3	618	5	584	2e-06	61.6
rs:WP_014558438	reverse gyrase [Fervidicoccus fontis].	22.99	435	252	15	181	583	862	1245	2e-06	61.6
rs:XP_001962812	GF14242 [Drosophila ananassae].	25.00	400	231	19	188	560	206	563	2e-06	61.6
rs:WP_014323368	DNA topoisomerase I [Desulfovibrio desulfuricans].	22.34	573	354	19	88	616	62	587	2e-06	61.6
rs:WP_002695772	DNA topoisomerase I [Microscilla marina].	24.51	559	338	21	77	596	53	566	2e-06	61.6
rs:WP_002789823	DNA topoisomerase I [Campylobacter coli].	21.42	649	408	22	3	618	5	584	2e-06	61.6
rs:WP_032816953	DNA topoisomerase I, partial [Gardnerella vaginalis].	25.93	324	186	12	271	571	5	297	2e-06	60.5
rs:WP_002856309	MULTISPECIES: DNA topoisomerase I [Campylobacter].	21.42	649	408	22	3	618	5	584	2e-06	61.6
rs:WP_030240907	DNA topoisomerase I [Streptomyces sp. NRRL S-350].	22.54	599	333	24	2	530	12	549	2e-06	61.6
rs:WP_004794516	DNA topoisomerase I [Mycoplasma canis].	21.29	634	392	26	39	629	24	593	2e-06	61.2
tr:A0A061IZH5_TRYRA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	19.76	678	451	22	3	633	5	636	2e-06	61.6
tr:A9XAV7_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.58	137	84	2	188	317	61	197	2e-06	58.9
tr:U1M2T6_ASCSU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.90	428	280	17	188	596	389	785	2e-06	61.6
tr:A9X8U9_LISDA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.58	137	84	2	188	317	50	186	2e-06	58.9
rs:WP_005390799	DNA topoisomerase I [Corynebacterium glucuronolyticum].	23.95	476	280	14	103	530	94	535	2e-06	61.6
tr:A9X8Z5_VIBNE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.58	137	84	2	188	317	56	192	2e-06	58.9
rs:WP_012946826	DNA topoisomerase I [Geodermatophilus obscurus].	22.05	635	346	28	32	574	51	628	2e-06	61.6
rs:WP_004795674	DNA topoisomerase I [Mycoplasma canis].	21.20	632	395	26	39	629	24	593	2e-06	61.2
tr:K2F4W4_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.97	505	282	18	188	629	1	461	2e-06	61.2
rs:WP_022541611	reverse gyrase [Aeropyrum camini].	23.10	355	222	10	82	415	663	987	2e-06	61.6
tr:C4K2S3_RICPU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.79	702	401	28	1	629	1	627	2e-06	61.6
tr:V6LJL7_9EUKA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.59	657	371	27	3	586	4	602	2e-06	61.2
tr:C7VGD0_ENTFL	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EEU69797.1};	33.04	115	72	2	497	611	6	115	2e-06	58.9
tr:A0A077ZCG1_TRITR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.71	388	239	14	188	560	208	553	2e-06	61.6
rs:WP_032973213	DNA topoisomerase I, partial [Stenotrophomonas maltophilia].	23.87	310	187	10	252	538	12	295	2e-06	61.2
tr:K1ZTJ0_9BACT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EKD41014.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EKD41014.1};	22.22	585	375	21	55	592	34	585	2e-06	61.2
rs:WP_020366069	hypothetical protein, partial [Staphylococcus epidermidis].	36.72	128	72	6	244	365	8	132	2e-06	57.8
tr:A0A0A1G470_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.58	137	84	2	188	317	53	189	2e-06	58.9
tr:X2HCF0_9GAMM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AHN27266.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AHN27266.1};	35.29	102	64	2	427	527	9	109	2e-06	57.8
tr:A9X905_VIBPR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.48	162	92	4	188	342	57	206	3e-06	58.9
rs:XP_005691821	PREDICTED: DNA topoisomerase 3-beta-1 [Capra hircus].	22.60	354	227	12	3	320	5	347	3e-06	60.8
tr:I1T8P1_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	29.09	165	102	3	187	344	59	215	3e-06	58.9
rs:WP_023547745	DNA topoisomerase I [Streptomyces roseochromogenus].	22.05	594	339	21	2	530	13	547	3e-06	61.2
rs:WP_025186797	hypothetical protein, partial [Enterococcus faecalis].	33.04	115	72	2	497	611	6	115	3e-06	58.9
tr:C2CKR7_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEI81836.1};	38.71	93	57	0	487	579	6	98	3e-06	57.4
tr:A0A098E8V4_9ZZZZ	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:CEG12462.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEG12462.1};	24.75	202	117	5	446	630	62	245	3e-06	60.1
rs:WP_009529784	topoisomerase [Peptostreptococcaceae bacterium CM5].	37.36	91	57	0	497	587	16	106	3e-06	57.4
rs:WP_002829326	DNA topoisomerase I [Campylobacter coli].	21.42	649	408	22	3	618	5	584	3e-06	61.2
rs:WP_013349813	DNA topoisomerase I [Arthrobacter arilaitensis].	23.02	504	315	17	80	538	79	554	3e-06	61.2
tr:F6JJ45_DROSI	SubName: Full=CG3458 {ECO:0000313|EMBL:ADG51428.1}; Flags: Fragment;	24.02	204	130	5	358	557	43	225	3e-06	58.9
rs:WP_038559666	DNA topoisomerase I [Neorickettsia helminthoeca].	22.54	701	398	28	1	629	1	628	3e-06	61.2
rs:WP_020941373	DNA topoisomerase I [Streptomyces collinus].	22.05	594	339	21	2	530	13	547	3e-06	61.2
rs:WP_013430517	reverse gyrase [Caldicellulosiruptor kronotskyensis].	23.74	396	225	13	157	536	737	1071	3e-06	61.2
tr:A3ZX95_9PLAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.33	627	379	20	3	574	12	585	3e-06	61.2
rs:XP_011942699	PREDICTED: DNA topoisomerase 3-alpha [Cercocebus atys].	21.63	467	308	14	188	619	239	682	3e-06	61.2
rs:WP_030177274	DNA topoisomerase I [Streptomyces sp. NRRL S-813].	22.05	594	339	21	2	530	13	547	3e-06	61.2
rs:WP_003935250	DNA topoisomerase I subunit omega [Rhodococcus ruber].	22.32	587	347	21	2	530	17	552	3e-06	61.2
rs:XP_011129487	putative DNA topoisomerase III [Gregarina niphandrodes].	21.41	439	296	14	163	577	174	587	3e-06	61.2
rs:WP_002839175	DNA topoisomerase I [Campylobacter coli].	21.57	649	407	22	3	618	5	584	3e-06	61.2
tr:E2RUL9_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.46	197	105	6	163	344	20	199	3e-06	58.2
tr:V7Z562_LACPN	RecName: Full=DNA topoisomerase I, plasmid {ECO:0000256|SAAS:SAAS00003555}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	22.27	476	311	17	90	540	109	550	3e-06	60.8
rs:WP_009530109	hypothetical protein, partial [Peptostreptococcaceae bacterium CM5].	42.31	78	45	0	497	574	16	93	3e-06	57.0
tr:W7HVY4_9PEZI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.01	468	303	17	82	520	93	527	3e-06	61.2
rs:WP_045273629	DNA topoisomerase I [Microbacterium azadirachtae].	23.33	300	190	7	256	538	251	527	3e-06	61.2
rs:WP_039065471	DNA topoisomerase III, partial [Shigella boydii].	36.90	84	53	0	348	431	8	91	3e-06	57.4
tr:T0ZAK0_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD44996.1}; Flags: Fragment;	38.82	85	48	1	139	219	1	85	3e-06	58.2
rs:WP_037850552	DNA topoisomerase I [Streptomyces sp. NRRL S-340].	22.11	597	335	22	2	530	13	547	3e-06	61.2
tr:F3KA07_PSEAJ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGH94019.1}; Flags: Fragment;	44.78	67	33	1	161	223	1	67	3e-06	56.6
rs:WP_029296505	DNA topoisomerase I [Chryseobacterium hispalense].	23.21	418	231	12	3	392	5	360	3e-06	61.2
rs:WP_030795887	DNA topoisomerase I [Streptomyces sp. NRRL F-5008].	22.15	596	336	22	2	530	13	547	3e-06	61.2
rs:WP_025446183	DNA topoisomerase I, partial [Helicobacter pylori].	24.07	324	217	8	99	399	77	394	3e-06	60.5
tr:V5UVI1_9VIBR	SubName: Full=Topoisomerase I {ECO:0000313|EMBL:AHB81948.1}; Flags: Fragment;	32.86	140	71	4	188	312	9	140	3e-06	57.8
gpu:CP010088_750	DNA topoisomerase family protein [Bacillus thuringiensis]	27.63	152	93	2	244	384	13	158	3e-06	57.8
rs:WP_005728009	topoisomerase I [Lactobacillus crispatus].	24.95	489	290	22	3	443	5	464	3e-06	61.2
rs:XP_001448873	hypothetical protein [Paramecium tetraurelia strain d4-2].	20.95	630	395	25	3	581	16	593	3e-06	61.2
rs:WP_002529660	DNA topoisomerase I [Propionibacterium acnes].	22.87	586	341	23	3	530	7	539	3e-06	61.2
rs:WP_021307189	DNA topoisomerase I [Helicobacter pylori].	22.81	640	402	25	3	614	4	579	3e-06	60.8
rs:WP_002800263	DNA topoisomerase I [Campylobacter coli].	21.57	649	407	22	3	618	5	584	3e-06	60.8
rs:WP_012571288	reverse gyrase [Thermococcus onnurineus].	24.95	457	240	19	162	579	829	1221	3e-06	61.2
tr:H6R9X3_NOCCG	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.67	600	329	21	4	530	1	538	3e-06	61.2
tr:I2G8N6_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.65	139	88	2	188	319	21	159	3e-06	58.2
rs:WP_037933747	DNA topoisomerase I [Streptomyces toyocaensis].	22.18	595	337	21	2	530	13	547	3e-06	61.2
tr:S3C9V8_OPHP1	SubName: Full=Dna topoisomerase iii {ECO:0000313|EMBL:EPE10284.1};	20.10	587	353	20	3	525	5	539	3e-06	60.8
rs:WP_031164975	DNA topoisomerase I [Streptomyces durhamensis].	22.11	597	335	22	2	530	13	547	3e-06	61.2
rs:WP_043103248	hypothetical protein, partial [Pseudomonas aeruginosa].	33.33	72	47	1	42	112	1	72	3e-06	56.6
rs:WP_002841473	DNA topoisomerase I [Campylobacter coli].	21.42	649	408	22	3	618	5	584	3e-06	60.8
rs:WP_045730466	DNA topoisomerase I [Arthrobacter chlorophenolicus].	21.77	588	364	21	2	538	10	552	3e-06	61.2
rs:WP_018354201	DNA topoisomerase I [Mycobacterium hassiacum].	22.37	590	347	23	2	530	16	555	3e-06	61.2
rs:WP_021368816	DNA topoisomerase [Peptoclostridium difficile].	36.26	91	58	0	497	587	16	106	3e-06	57.0
tr:A9YJ49_DROME	SubName: Full=Topoisomerase 3 beta {ECO:0000313|EMBL:ABW92701.1}; Flags: Fragment;	23.41	205	132	5	357	557	45	228	3e-06	59.3
rs:WP_009946467	DNA topoisomerase I [Saccharopolyspora erythraea].	24.87	591	325	27	3	530	1	535	3e-06	61.2
rs:WP_013882357	DNA topoisomerase I [[Cellvibrio] gilvus].	22.63	623	373	22	2	563	6	580	3e-06	61.2
tr:A9XAW1_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	29.88	164	100	3	188	344	60	215	3e-06	58.5
rs:WP_021084556	DNA topoisomerase I [Campylobacter concisus].	22.84	661	410	25	3	629	4	598	3e-06	60.8
rs:WP_030161843	DNA topoisomerase I [Glycomyces sp. NRRL B-16210].	24.18	426	250	18	185	564	178	576	3e-06	61.2
rs:XP_007671879	hypothetical protein BAUCODRAFT_60941 [Baudoinia compniacensis UAMH 10762].	21.22	589	366	19	3	541	6	546	3e-06	60.8
rs:WP_039649009	DNA topoisomerase I [Campylobacter insulaenigrae].	24.16	418	257	14	3	396	4	385	3e-06	60.8
rs:WP_041662546	DNA topoisomerase I [Streptomyces venezuelae].	22.00	591	343	21	2	530	13	547	3e-06	61.2
tr:F6JNP0_DROSI	SubName: Full=CG3458 {ECO:0000313|EMBL:ADG51466.1}; Flags: Fragment;	24.02	204	130	5	358	557	43	225	3e-06	58.5
rs:WP_036639944	hypothetical protein, partial [Paenibacillus durus].	29.17	120	68	1	462	581	5	107	3e-06	57.4
rs:WP_037620543	hypothetical protein, partial [Streptococcus parauberis].	34.48	87	57	0	428	514	7	93	3e-06	57.0
rs:WP_034289746	DNA topoisomerase I [Amycolatopsis benzoatilytica].	21.73	612	322	24	2	530	20	557	3e-06	60.8
rs:WP_035913299	DNA topoisomerase I [Lechevalieria aerocolonigenes].	22.86	595	333	25	3	530	1	536	3e-06	60.8
rs:WP_005772516	DNA topoisomerase III, partial [Pseudomonas amygdali].	36.17	94	60	0	488	581	2	95	3e-06	57.8
rs:XP_011652538	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC101210823 [Cucumis sativus].	25.17	298	185	11	64	331	395	684	3e-06	61.2
tr:A0A0A6N559_9THEM	RecName: Full=Reverse gyrase {ECO:0000256|RuleBase:RU004026};	22.46	472	278	16	3	429	544	972	3e-06	60.8
rs:WP_004317674	DNA topoisomerase I [Campylobacter concisus].	22.84	661	410	25	3	629	4	598	3e-06	60.8
rs:WP_040352784	DNA topoisomerase I, partial [Blastopirellula marina].	22.33	627	379	20	3	574	2	575	4e-06	60.8
rs:WP_015583347	DNA topoisomerase I [Propionibacterium avidum].	22.26	611	314	27	3	530	7	539	4e-06	60.8
rs:XP_005962581	PREDICTED: DNA topoisomerase 3-beta-1-like [Pantholops hodgsonii].	22.88	354	226	12	3	320	5	347	4e-06	60.8
rs:WP_000932884	DNA topoisomerase III [Bacillus cereus].	30.70	114	67	4	3	108	7	116	4e-06	57.4
tr:S7XLM7_SPRLO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EPR79984.1}; Flags: Fragment;	22.17	618	379	21	3	543	6	598	4e-06	60.8
rs:WP_021816160	hypothetical protein [Lactobacillus fermentum].	31.78	107	71	2	3	107	4	110	4e-06	57.0
tr:I7AV34_PSEPT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.48	151	97	2	186	329	195	341	4e-06	59.7
rs:XP_009798206	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Nicotiana sylvestris].	24.50	347	218	12	3	314	16	353	4e-06	60.5
rs:WP_045501272	DNA topoisomerase I [Chryseobacterium sp. StRB126].	23.44	418	230	12	3	392	5	360	4e-06	60.8
rs:WP_021088986	DNA topoisomerase I [Campylobacter concisus].	23.00	661	409	25	3	629	4	598	4e-06	60.8
tr:G0NRK3_CAEBE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.86	433	278	14	188	594	211	613	4e-06	60.8
tr:G3CKD4_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.97	147	77	4	188	319	49	187	4e-06	58.2
rs:WP_044382392	DNA topoisomerase I [Streptomyces cyaneogriseus].	24.56	281	158	9	273	530	310	559	4e-06	60.8
rs:WP_029108391	DNA topoisomerase I [Mycobacterium sp. URHD0025].	22.49	587	350	22	2	530	15	554	4e-06	60.8
tr:A9X915_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.29	163	97	3	188	343	56	210	4e-06	58.2
tr:L0P8R6_PNEJ8	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.40	616	364	23	3	556	18	581	4e-06	60.5
rs:WP_027304177	DNA topoisomerase I [Campylobacter upsaliensis].	22.81	434	271	16	3	410	5	400	4e-06	60.8
rs:WP_013889909	DNA topoisomerase I [Helicobacter bizzozeronii].	21.93	579	351	20	2	530	7	534	4e-06	60.8
rs:WP_028810409	DNA topoisomerase I [Streptomyces flavidovirens].	22.09	593	339	23	2	530	13	546	4e-06	60.8
tr:W8PPG8_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.18	426	250	18	185	564	174	572	4e-06	60.8
rs:WP_010595034	MULTISPECIES: DNA topoisomerase I [Rhodococcus].	22.32	587	347	21	2	530	17	552	4e-06	60.8
rs:WP_021611891	DNA topoisomerase I [Actinomyces sp. oral taxon 172].	23.03	634	374	27	2	571	5	588	4e-06	60.8
tr:U1EIY6_ENTGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.43	314	183	13	273	564	7	294	4e-06	59.3
rs:WP_033778214	DNA topoisomerase I, partial [Helicobacter pylori].	27.20	239	148	7	99	317	77	309	4e-06	60.1
rs:WP_016820164	DNA topoisomerase, partial [Gardnerella vaginalis].	26.39	341	163	13	271	571	66	358	4e-06	60.5
tr:A0A087TZV0_9ARAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.13	294	188	8	282	564	3	269	4e-06	60.5
tr:H2SSS7_TAKRU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.75	158	85	4	251	395	222	366	4e-06	60.8
tr:A9X8V1_LISDA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.58	137	84	2	188	317	53	189	4e-06	58.2
rs:WP_044278325	hypothetical protein [Campylobacter jejuni].	27.60	221	131	7	473	669	2	217	4e-06	58.5
rs:WP_018118313	DNA topoisomerase I [Corynebacterium mastitidis].	22.54	559	334	15	77	571	75	598	4e-06	60.8
tr:E7BUA8_VIBCL	RecName: Full=DNA topoisomerase; EC=5.99.1.2; Flags: Fragment;	32.19	146	76	5	187	317	47	184	4e-06	57.8
tr:D8VNQ6_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.58	137	84	2	188	317	32	168	4e-06	57.4
tr:J6D7M6_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EJX92842.1};	32.62	141	90	4	3	139	4	143	4e-06	57.4
rs:WP_040163339	hypothetical protein, partial [Helicobacter pylori].	27.66	235	144	7	103	317	81	309	4e-06	59.7
rs:WP_024885813	DNA topoisomerase I [Streptomyces sp. CNH189].	21.81	596	338	21	2	530	13	547	4e-06	60.8
rs:XP_002159450	PREDICTED: DNA topoisomerase 3-alpha-like [Hydra vulgaris].	23.42	427	245	16	248	634	4	388	4e-06	60.5
tr:K5BE85_9MYCO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.37	590	347	23	2	530	3	542	4e-06	60.5
rs:XP_003019829	hypothetical protein TRV_06117 [Trichophyton verrucosum HKI 0517].	22.26	620	372	24	3	560	6	577	5e-06	60.5
tr:A0A090T6U4_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	35.19	108	58	5	289	388	1	104	5e-06	56.6
rs:WP_021092863	DNA topoisomerase I [Campylobacter concisus].	22.36	662	412	24	3	629	4	598	5e-06	60.5
tr:F4CIS0_PSEUX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.73	594	335	25	2	530	40	574	5e-06	60.5
rs:WP_004797058	DNA topoisomerase I [Mycoplasma canis].	21.29	634	392	26	39	629	24	593	5e-06	60.5
rs:WP_032840374	DNA topoisomerase I, partial [Gardnerella vaginalis].	26.20	332	175	12	271	571	12	304	5e-06	60.5
rs:WP_032819214	DNA topoisomerase I, partial [Gardnerella vaginalis].	25.78	322	189	11	271	571	7	299	5e-06	60.5
tr:A7ZFR7_CAMC1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.84	661	410	25	3	629	4	598	5e-06	60.5
rs:WP_011892291	DNA topoisomerase I [Mycobacterium gilvum].	22.28	597	339	22	2	530	16	555	5e-06	60.5
rs:WP_002547495	DNA topoisomerase I [Propionibacterium acnes].	21.32	605	327	23	3	530	7	539	5e-06	60.5
rs:WP_018187056	DNA topoisomerase I [Microbacterium paraoxydans].	23.06	503	310	17	81	538	73	543	5e-06	60.5
rs:WP_033321736	DNA topoisomerase I [Streptomyces yerevanensis].	21.86	590	345	22	2	530	13	547	5e-06	60.5
tr:A4NVC9_HAEIF	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EDK14859.1};	35.11	94	50	5	1	90	1	87	5e-06	56.2
tr:F6JJ32_DROSI	SubName: Full=CG3458 {ECO:0000313|EMBL:ADG51415.1}; Flags: Fragment;	23.53	204	131	5	358	557	43	225	5e-06	58.2
rs:WP_009294935	DNA topoisomerase I [Campylobacter sp. 10_1_50].	22.84	661	410	25	3	629	4	598	5e-06	60.5
rs:WP_010723776	hypothetical protein [Enterococcus faecium].	29.92	127	60	5	3	111	4	119	5e-06	57.0
rs:WP_045190613	DNA topoisomerase I [Terrabacter sp. 28].	22.17	591	344	23	2	530	8	544	5e-06	60.5
rs:WP_034588384	hypothetical protein [Clostridiales bacterium VE202-15].	30.77	117	75	3	467	578	26	141	5e-06	57.4
rs:WP_044092589	DNA topoisomerase I [Bifidobacterium thermacidophilum].	21.20	651	384	22	2	571	6	608	5e-06	60.5
tr:A9X8V6_PHOPO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.33	138	83	4	188	317	49	185	5e-06	57.8
rs:XP_003675634	hypothetical protein NCAS_0C02780 [Naumovozyma castellii CBS 4309].	22.30	426	263	15	188	574	237	633	5e-06	60.5
rs:WP_002512962	DNA topoisomerase I [Propionibacterium acnes].	21.32	605	327	23	3	530	7	539	5e-06	60.5
tr:K1TQR3_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC72068.1}; Flags: Fragment;	40.26	77	32	3	1	72	1	68	5e-06	55.8
rs:WP_030225040	DNA topoisomerase I [Streptomyces sp. NRRL WC-3626].	21.85	595	339	21	2	530	13	547	5e-06	60.5
tr:A9X904_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.85	137	85	2	188	317	56	192	5e-06	57.8
rs:WP_042827053	DNA topoisomerase I, partial [Xanthomonas axonopodis].	25.66	226	148	6	100	314	75	291	5e-06	58.9
rs:XP_010328854	PREDICTED: DNA topoisomerase 3-beta-1 [Saimiri boliviensis boliviensis].	21.83	371	236	11	225	585	238	564	5e-06	60.5
tr:I3ET23_NEMP1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.49	610	395	18	3	571	4	564	5e-06	60.5
tr:A9X8W8_VIBCL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.19	146	76	5	187	317	56	193	5e-06	57.8
rs:WP_006170276	DNA topoisomerase I [Synechococcus sp. WH 5701].	21.88	448	288	14	157	566	145	568	5e-06	60.5
tr:A9X8W7_VIBCL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.19	146	76	5	187	317	50	187	5e-06	57.8
rs:WP_030981908	DNA topoisomerase I [Streptomyces sp. NRRL WC-3744].	22.18	595	337	21	2	530	13	547	5e-06	60.5
tr:A9X8W9_VIBCL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.19	146	76	5	187	317	55	192	5e-06	57.8
rs:WP_022874262	DNA topoisomerase I [Arthrobacter sp. PAO19].	23.41	504	313	16	80	538	79	554	6e-06	60.5
rs:WP_030651338	MULTISPECIES: DNA topoisomerase I [Streptomyces].	22.18	595	337	21	2	530	13	547	6e-06	60.5
tr:I2G8M4_9VIBR	RecName: Full=DNA topoisomerase; EC=5.99.1.2; Flags: Fragment;	31.65	139	88	2	188	319	21	159	6e-06	57.4
rs:WP_033788576	DNA topoisomerase I, partial [Helicobacter pylori].	24.07	324	217	8	99	399	77	394	6e-06	59.7
tr:B9VRR6_9BACT	SubName: Full=TopR {ECO:0000313|EMBL:ACM09965.1}; Flags: Fragment;	30.46	151	88	4	163	312	3	137	6e-06	57.0
tr:I2G8N2_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.65	139	88	2	188	319	21	159	6e-06	57.4
tr:W4UH72_PROAA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.32	605	327	23	3	530	7	539	6e-06	60.5
rs:WP_023033786	MULTISPECIES: DNA topoisomerase I [Propionibacterium].	21.32	605	327	23	3	530	7	539	6e-06	60.5
rs:WP_033775322	DNA topoisomerase [Helicobacter pylori].	27.20	239	148	7	99	317	77	309	6e-06	59.3
rs:WP_034905489	DNA topoisomerase I [Campylobacter sp. MIT 97-5078].	22.15	650	402	21	3	618	4	583	6e-06	60.1
rs:WP_003999165	DNA topoisomerase [Streptomyces viridochromogenes].	22.32	596	335	23	2	530	13	547	6e-06	60.5
tr:I2G8N5_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.65	139	88	2	188	319	21	159	6e-06	57.4
tr:A9X911_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.19	146	76	4	187	317	56	193	6e-06	57.8
rs:WP_002549474	DNA topoisomerase I [Propionibacterium acnes].	21.93	611	316	27	3	530	7	539	6e-06	60.1
rs:WP_028700909	DNA topoisomerase I [Propionibacterium acidipropionici].	21.90	630	363	26	3	560	7	579	6e-06	60.1
rs:WP_002531648	DNA topoisomerase I [Propionibacterium acnes].	21.32	605	327	23	3	530	7	539	6e-06	60.1
rs:WP_029656512	DNA topoisomerase, partial [Enterococcus faecalis].	35.88	131	69	5	154	269	5	135	6e-06	56.6
rs:WP_032836650	DNA topoisomerase I, partial [Gardnerella vaginalis].	26.35	334	172	13	271	571	17	309	6e-06	60.1
rs:WP_031062705	DNA topoisomerase I [Streptomyces sp. NRRL F-5527].	22.33	600	330	24	2	530	13	547	6e-06	60.1
rs:WP_026823893	hypothetical protein [Arsenophonus nasoniae].	27.67	159	110	3	517	673	8	163	6e-06	57.0
tr:N1Q2F9_DOTSN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	20.74	569	363	19	3	525	6	532	6e-06	60.1
rs:WP_031092069	MULTISPECIES: DNA topoisomerase I [Streptomyces].	22.18	595	337	21	2	530	13	547	6e-06	60.1
rs:WP_004321457	DNA topoisomerase I [Campylobacter showae].	21.69	650	405	24	3	618	4	583	6e-06	60.1
tr:U6NV32_HAECO	SubName: Full=Toprim and DNA topoisomerase domain containing protein {ECO:0000313|EMBL:CDJ84401.1}; Flags: Fragment;	20.27	656	425	21	3	602	5	618	6e-06	60.5
tr:V5UVL6_9GAMM	SubName: Full=Topoisomerase I {ECO:0000313|EMBL:AHB81942.1}; Flags: Fragment;	32.58	132	82	2	188	312	9	140	6e-06	56.6
rs:WP_031028009	DNA topoisomerase I [Streptomyces sp. NRRL WC-3725].	22.18	595	337	21	2	530	13	547	6e-06	60.1
rs:WP_001898027	DNA topoisomerase I [Helicobacter pylori].	23.76	362	235	10	82	409	61	415	6e-06	59.3
rs:WP_003773150	DNA topoisomerase I [Erysipelothrix rhusiopathiae].	25.91	467	285	18	77	519	56	485	6e-06	60.1
tr:A9X8V7_PHOPO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.37	139	85	4	187	317	62	199	6e-06	57.8
rs:WP_036397702	DNA topoisomerase I [Mycobacterium cosmeticum].	22.54	590	346	22	2	530	16	555	6e-06	60.1
rs:WP_035107281	DNA topoisomerase I [Corynebacterium camporealensis].	23.40	517	315	17	103	571	100	583	7e-06	60.1
tr:A0A0A1G3K0_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.64	173	89	5	186	343	49	205	7e-06	57.4
rs:WP_046204013	DNA topoisomerase I [Corynebacterium argentoratense].	22.76	558	331	19	36	530	28	548	7e-06	60.1
rs:XP_004182129	hypothetical protein TBLA_0H03290 [Tetrapisispora blattae CBS 6284].	22.28	413	249	13	188	560	235	615	7e-06	59.7
tr:I2G8M0_9VIBR	RecName: Full=DNA topoisomerase; EC=5.99.1.2; Flags: Fragment;	31.65	139	88	2	188	319	21	159	7e-06	57.0
rs:WP_005772953	DNA topoisomerase III, partial [Pseudomonas amygdali].	28.44	109	72	2	1	108	5	108	7e-06	56.2
rs:WP_045433809	DNA topoisomerase I [Mycoplasma canadense].	22.86	630	356	27	73	641	50	610	7e-06	59.7
rs:WP_025192292	hypothetical protein, partial [Enterococcus faecalis].	35.88	131	69	5	154	269	5	135	7e-06	56.6
tr:A9X8Z1_VIBNA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.81	172	88	5	187	343	55	210	7e-06	57.4
rs:WP_031020068	DNA topoisomerase I [Streptomyces sp. NRRL S-1314].	22.24	598	333	23	2	530	13	547	7e-06	60.1
rs:WP_006132575	DNA topoisomerase I [Streptomyces gancidicus].	22.24	598	333	23	2	530	13	547	7e-06	60.1
rs:WP_030209244	DNA topoisomerase I [Streptomyces griseoluteus].	22.07	598	334	22	2	530	13	547	7e-06	60.1
rs:WP_024455846	DNA topoisomerase I [Mycobacterium sp. UM_RHS].	22.54	590	346	22	2	530	16	555	7e-06	60.1
tr:A0A090PNC3_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.27	275	142	12	75	317	85	333	7e-06	58.9
tr:A9X8Y9_VIBMI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.94	144	91	3	188	324	56	199	7e-06	57.4
tr:D3XTF0_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.39	137	87	2	188	317	52	188	7e-06	57.4
rs:WP_013852723	DNA topoisomerase I [Erysipelothrix rhusiopathiae].	25.91	467	285	18	77	519	56	485	7e-06	59.7
rs:WP_010882584	topoisomerase I [Helicobacter pylori].	23.08	325	219	10	99	399	77	394	7e-06	59.3
tr:A0A094QAU3_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KGA21365.1};	21.56	589	336	20	2	528	12	536	7e-06	60.1
rs:XP_007513181	DNA topoisomerase I [Bathycoccus prasinos].	26.74	273	149	10	157	392	268	526	7e-06	60.1
rs:WP_031072374	DNA topoisomerase I [Streptomyces sp. NRRL WC-3742].	22.04	599	336	23	2	530	12	549	7e-06	60.1
tr:A0A0B8PSF8_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	35.00	100	60	3	268	362	71	170	8e-06	57.0
tr:I1T8P4_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.88	146	75	4	187	317	59	196	8e-06	57.4
tr:I2G8M8_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.65	139	88	2	188	319	21	159	8e-06	57.0
rs:WP_005950772	hypothetical protein, partial [Blautia hydrogenotrophica].	25.78	353	205	16	90	407	67	397	8e-06	58.9
rs:WP_005323095	DNA topoisomerase I [Corynebacterium pseudogenitalium].	24.42	557	317	23	38	530	30	546	8e-06	60.1
tr:D8VNQ5_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.58	137	84	2	188	317	14	150	8e-06	56.6
tr:W4VMX9_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE94542.1};	31.58	95	65	0	345	439	29	123	8e-06	56.6
rs:WP_041364416	DNA topoisomerase I [Mycoplasma pulmonis].	21.70	599	358	24	2	564	3	526	8e-06	59.7
tr:G6ENW3_STRTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.95	141	89	3	188	314	69	209	8e-06	57.4
rs:WP_013775510	reverse gyrase [Acidianus hospitalis].	24.66	369	230	14	187	533	838	1180	8e-06	60.1
tr:R1W2K8_ENTFL	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOF30714.1}; Flags: Fragment;	35.88	131	69	5	154	269	1	131	8e-06	56.2
rs:WP_009829664	DNA topoisomerase I [Rhodobacteraceae bacterium HTCC2083].	22.18	559	359	18	1	534	1	508	8e-06	59.7
rs:WP_030828008	DNA topoisomerase I [Streptomyces sp. NRRL F-2305].	21.85	595	339	21	2	530	13	547	8e-06	59.7
tr:H2WGI4_CAEJA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.07	349	223	13	3	318	6	345	8e-06	58.9
rs:WP_004837884	hypothetical protein, partial [Anaerococcus tetradius].	44.71	85	44	1	467	551	2	83	8e-06	55.5
tr:A0A099VQ59_9HELI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	24.63	402	234	15	242	614	28	389	8e-06	59.3
tr:V5UWQ4_9VIBR	SubName: Full=Topoisomerase I {ECO:0000313|EMBL:AHB81959.1}; Flags: Fragment;	32.86	140	71	4	188	312	9	140	8e-06	56.2
rs:WP_035518990	DNA topoisomerase, partial [Burkholderia sp. Ch1-1].	25.13	195	123	7	498	676	7	194	8e-06	58.5
tr:X1M6J8_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_L03210 {ECO:0000313|EMBL:GAI10320.1}; Flags: Fragment;	26.52	230	157	5	90	312	61	285	8e-06	58.5
tr:B9VRS4_9BACT	SubName: Full=TopR {ECO:0000313|EMBL:ACM09973.1}; Flags: Fragment;	30.67	163	81	6	163	318	3	140	8e-06	56.2
tr:A0A089VER1_VIBPH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.58	137	84	3	188	317	36	172	8e-06	57.0
tr:B7XDE0_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.61	138	84	4	188	317	45	181	8e-06	57.0
rs:WP_004601140	DNA topoisomerase I [Turicella otitidis].	24.30	395	226	14	185	530	177	547	9e-06	59.7
tr:T0KVV8_9NEIS	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQB59647.1}; Flags: Fragment;	24.68	235	151	8	430	651	40	261	9e-06	58.9
rs:WP_015309699	DNA topoisomerase I [Mycobacterium smegmatis].	22.60	593	342	22	2	530	16	555	9e-06	59.7
gpu:KP402080_1	topoisomerase I [Vibrio parahaemolyticus]	33.33	144	77	4	187	317	53	190	9e-06	56.6
rs:WP_046733332	DNA topoisomerase I [Streptomyces sp. MUSC119T].	22.02	595	338	21	2	530	13	547	9e-06	59.7
tr:I2G8M6_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.65	139	88	2	188	319	21	159	9e-06	56.6
tr:Q98Q95_MYCPU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.70	599	358	24	2	564	9	532	9e-06	59.3
rs:WP_037620536	hypothetical protein, partial [Streptococcus parauberis].	36.71	79	50	0	436	514	15	93	9e-06	55.5
tr:A0A059ZZL0_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.85	137	85	2	188	317	51	187	9e-06	57.0
tr:G4Y217_VIBNA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.81	172	88	5	187	343	58	213	9e-06	57.4
rs:WP_034581636	DNA topoisomerase I [Helicobacter bizzozeronii].	22.98	396	255	13	156	530	160	526	9e-06	59.7
rs:WP_022263701	ATPase AAA [Clostridium sp. CAG:352].	36.13	119	66	5	460	576	71	181	9e-06	56.6
tr:A0A0A1G6S9_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.64	173	89	5	186	343	52	208	9e-06	57.4
rs:WP_020975460	DNA topoisomerase I [Corynebacterium argentoratense].	22.76	558	331	19	36	530	28	548	9e-06	59.7
rs:WP_022495448	DNA topoisomerase [Ruminococcus sp. CAG:624].	26.75	329	203	11	90	392	66	382	9e-06	59.3
rs:WP_010358422	DNA topoisomerase I [Streptomyces acidiscabies].	22.11	597	335	23	2	530	13	547	9e-06	59.7
tr:H5V9T9_HELBI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.98	396	255	13	156	530	158	524	9e-06	59.7
rs:WP_010154970	DNA topoisomerase I [Leucobacter chromiiresistens].	22.13	601	341	22	2	530	6	551	9e-06	59.7
rs:WP_035837563	DNA topoisomerase I [Cryobacterium roopkundense].	22.35	519	298	17	77	528	69	549	9e-06	59.7
tr:A9X900_VIBPH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.41	194	107	6	163	343	30	208	9e-06	57.0
rs:WP_004796196	DNA topoisomerase I [Mycoplasma canis].	21.14	634	393	26	39	629	24	593	9e-06	59.3
tr:I2G8M7_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.65	139	88	2	188	319	21	159	9e-06	56.6
tr:A0A009GGC7_ACIBA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.00	332	211	12	75	385	99	413	9e-06	58.9
tr:A9X8Z0_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.33	138	85	3	187	317	55	192	9e-06	57.0
tr:X1J6I9_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S16825 {ECO:0000313|EMBL:GAH65373.1}; Flags: Fragment;	26.90	197	125	6	186	366	65	258	9e-06	57.8
rs:WP_020757403	DNA topoisomerase, partial [Gardnerella vaginalis].	26.20	332	175	12	271	571	63	355	1e-05	59.3
tr:M9SZE8_VIBNA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.81	172	88	5	187	343	62	217	1e-05	57.4
rs:WP_031128143	DNA topoisomerase I [Streptomyces sp. NRRL WC-3719].	21.69	590	346	21	2	530	13	547	1e-05	59.7
rs:WP_035879967	DNA topoisomerase I, partial [Cryobacterium sp. MLB-32].	22.54	519	297	17	77	528	69	549	1e-05	59.7
rs:WP_018578850	DNA topoisomerase I [Erysipelothrix tonsillarum].	25.85	468	284	18	77	519	56	485	1e-05	59.3
rs:WP_046643722	DNA topoisomerase I [Turicella otitidis].	24.30	395	226	14	185	530	177	547	1e-05	59.7
rs:WP_035111286	DNA topoisomerase I [Corynebacterium freiburgense].	25.05	503	292	19	80	530	80	549	1e-05	59.7
tr:W0NMP1_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.65	139	88	2	188	319	38	176	1e-05	56.6
rs:WP_001952168	DNA topoisomerase [Helicobacter pylori].	26.17	256	162	8	82	317	61	309	1e-05	58.5
rs:WP_020098197	DNA topoisomerase I [Microbacterium sp. 11MF].	23.06	503	310	17	81	538	73	543	1e-05	59.3