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TARA_ERS490053_N000891_2 / Result of BLASTP

browse BLASTP result of all genes from this scaffold

subject	subject definition	idt	len	mis	gap	q.start	q.end	s.start	s.end	evalue	bit.score
subject	subject definition	idt	len	mis	gap	q.start	q.end	s.start	s.end	evalue	bit.score
rs:WP_021444245	hypothetical protein, partial [Pseudomonas sp. EGD-AK9].	94.76	458	24	0	2	459	29	486	0.0	842
rs:WP_006122511	MULTISPECIES: DNA topoisomerase [Proteobacteria].	94.98	458	23	0	2	459	217	674	0.0	842
rs:WP_011114056	MULTISPECIES: DNA topoisomerase [Bacteria].	94.98	458	23	0	2	459	217	674	0.0	841
rs:WP_031942852	DNA topoisomerase III [uncultured bacterium].	94.98	458	23	0	2	459	217	674	0.0	841
rs:WP_012805984	DNA topoisomerase III [Pseudomonas putida].	94.98	458	23	0	2	459	217	674	0.0	841
rs:WP_031943142	DNA processing protein [uncultured bacterium].	94.76	458	24	0	2	459	217	674	0.0	839
rs:WP_001235885	DNA topoisomerase [Salmonella enterica].	94.54	458	25	0	2	459	217	674	0.0	839
rs:WP_031942736	DNA topoisomerase III [uncultured bacterium].	94.54	458	25	0	2	459	217	674	0.0	839
rs:WP_011666398	DNA topoisomerase III [Bordetella pertussis].	94.32	458	26	0	2	459	217	674	0.0	836
rs:WP_011222097	DNA topoisomerase [uncultured bacterium].	94.32	458	26	0	2	459	217	674	0.0	836
rs:WP_046832941	DNA topoisomerase [Xanthomonas axonopodis].	93.89	458	28	0	2	459	217	674	0.0	830
rs:WP_035622801	DNA topoisomerase [Hydrogenophaga intermedia].	86.90	458	60	0	2	459	217	674	0.0	826
rs:WP_039816568	DNA topoisomerase [Xanthomonas arboricola].	86.03	458	64	0	2	459	217	674	0.0	819
rs:WP_031942999	DNA processing protein [uncultured bacterium].	91.88	431	35	0	29	459	244	674	0.0	811
rs:WP_011013284	TraE protein [uncultured bacterium].	92.11	431	34	0	29	459	244	674	0.0	810
rs:WP_032495545	DNA processing protein, DNA topoisomerase [uncultured bacterium].	92.11	431	34	0	29	459	244	674	0.0	810
rs:WP_011304091	DNA topoisomerase III [Sphingomonas sp. A1].	91.88	431	35	0	29	459	244	674	0.0	810
rs:WP_011798734	DNA topoisomerase [Acidovorax sp. JS42].	91.88	431	35	0	29	459	244	674	0.0	808
rs:WP_015063384	DNA topoisomerase [Burkholderia cepacia].	91.65	431	36	0	29	459	244	674	0.0	808
rs:WP_031943088	DNA processing protein [uncultured bacterium].	91.88	431	35	0	29	459	244	674	0.0	808
rs:WP_011255183	MULTISPECIES: DNA topoisomerase [Burkholderiales].	91.65	431	36	0	29	459	244	674	0.0	808
rs:WP_014386463	DNA topoisomerase III [Comamonas testosteroni].	91.65	431	36	0	29	459	244	674	0.0	808
rs:WP_011600633	DNA topoisomerase [Hydrogenophaga intermedia].	87.24	431	54	1	29	459	244	673	0.0	793
rs:WP_015061639	DNA topoisomerase [Ralstonia pickettii].	87.24	431	54	1	29	459	244	673	0.0	791
rs:WP_031942764	DNA topoisomerase III [uncultured bacterium].	87.24	431	54	1	29	459	244	673	0.0	791
gpu:KM655311_26	TraE [uncultured bacterium]	87.01	431	55	1	29	459	244	673	0.0	788
rs:WP_036254279	DNA topoisomerase [Methylobacter sp. BBA5.1].	83.29	431	71	1	29	459	244	673	0.0	759
rs:WP_027156703	DNA topoisomerase [Methylobacter luteus].	82.60	431	74	1	29	459	244	673	0.0	751
rs:WP_036293444	DNA topoisomerase [Methylobacter whittenburyi].	79.12	431	90	0	29	459	244	674	0.0	731
rs:WP_031943975	DNA topoisomerase [uncultured bacterium pMCBF6].	79.12	431	89	1	29	459	244	673	0.0	721
rs:WP_011255049	DNA topoisomerase [Aromatoleum aromaticum].	79.49	434	84	1	31	459	246	679	0.0	720
rs:WP_017842783	DNA topoisomerase [Methylomicrobium buryatense].	77.96	431	94	1	29	459	244	673	0.0	714
rs:YP_004901792	DNA topoisomerase 3 (plasmid) [Methylomicrobium alcaliphilum 20Z].	77.73	431	95	1	29	459	244	673	0.0	710
tr:W7WV89_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	76.33	431	100	2	29	459	85	513	0.0	697
rs:WP_014708275	DNA topoisomerase [Methylophaga frappieri].	72.91	443	117	2	18	459	233	673	0.0	675
rs:WP_008929975	DNA topoisomerase [Alcanivorax hongdengensis].	72.91	443	117	2	18	459	233	673	0.0	675
rs:WP_047340352	DNA topoisomerase [Xanthomonas oryzae].	75.41	431	104	1	29	459	245	673	0.0	671
rs:WP_017168798	DNA topoisomerase [Xanthomonas axonopodis].	75.17	431	107	0	29	459	245	675	0.0	670
rs:WP_017169969	DNA topoisomerase [Xanthomonas axonopodis].	74.94	431	108	0	29	459	245	675	0.0	669
rs:WP_017121484	DNA topoisomerase [Xanthomonas vasicola].	74.94	431	108	0	29	459	245	675	0.0	669
rs:WP_017161201	DNA topoisomerase [Xanthomonas axonopodis].	74.94	431	108	0	29	459	245	675	0.0	668
rs:WP_014579488	DNA topoisomerase [Marinobacter adhaerens].	74.07	432	109	2	29	459	244	673	0.0	666
rs:WP_020933262	conjugal transfer protein TraE, DNA topoisomerase III [Cycloclasticus zancles].	72.91	443	117	2	18	459	233	673	0.0	665
rs:WP_017170471	DNA topoisomerase [Xanthomonas axonopodis].	74.71	431	109	0	29	459	245	675	0.0	665
rs:WP_017166887	DNA topoisomerase [Xanthomonas axonopodis].	74.71	431	109	0	29	459	245	675	0.0	662
rs:WP_017167698	DNA topoisomerase [Xanthomonas axonopodis].	74.48	431	110	0	29	459	245	675	0.0	661
rs:WP_020405854	DNA topoisomerase [Hahella ganghwensis].	68.51	451	138	2	9	459	225	671	0.0	660
rs:WP_042658661	DNA topoisomerase [Aeromonas allosaccharophila].	71.99	432	118	2	29	459	244	673	0.0	659
rs:WP_010676165	DNA topoisomerase [Aeromonas caviae].	71.76	432	119	2	29	459	244	673	0.0	659
rs:WP_046420451	DNA topoisomerase, partial [Xylella fastidiosa].	71.46	431	123	0	29	459	10	440	0.0	640
rs:WP_012774824	DNA topoisomerase III [Photobacterium damselae].	69.21	432	130	2	29	459	244	673	0.0	645
rs:WP_004086664	DNA topoisomerase [Xylella fastidiosa].	71.23	431	124	0	29	459	245	675	0.0	639
rs:WP_046417497	DNA topoisomerase [Xylella fastidiosa].	71.46	431	123	0	29	459	245	675	0.0	637
rs:WP_010894513	DNA topoisomerase [Xylella fastidiosa].	71.23	431	124	0	29	459	245	675	0.0	635
rs:WP_004091429	DNA topoisomerase [Xylella fastidiosa].	71.00	431	125	0	29	459	245	675	0.0	634
rs:WP_045900057	DNA topoisomerase, partial [Enterobacter cloacae].	92.92	339	24	0	2	340	40	378	0.0	596
rs:WP_010890147	hypothetical protein [Enterobacter aerogenes].	73.40	470	101	5	2	459	217	674	0.0	584
rs:WP_028386704	DNA topoisomerase [Legionella geestiana].	63.55	428	151	2	32	459	248	670	0.0	580
rs:WP_043763722	DNA topoisomerase, partial [Marichromatium purpuratum].	86.23	305	42	0	155	459	3	307	0.0	565
rs:WP_028389296	DNA topoisomerase [Legionella fairfieldensis].	62.18	431	158	2	29	459	245	670	0.0	577
tr:W0E1F8_MARPU	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:AHF04680.1};	86.23	305	42	0	155	459	14	318	0.0	564
rs:WP_047533031	DNA topoisomerase [Shewanella sp. ZOR0012].	58.93	431	172	1	29	459	244	669	0.0	555
tr:F3J716_PSEAP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	59.50	437	169	2	29	459	245	679	0.0	553
tr:A9L6T8_SHEB9	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	61.89	433	160	4	29	459	244	673	0.0	552
rs:WP_046935705	DNA topoisomerase [Xanthomonas euvesicatoria].	58.80	483	146	4	29	459	244	725	0.0	553
rs:WP_031943207	TraE DNA topoisomerase [uncultured bacterium].	57.97	483	150	4	29	459	244	725	0.0	550
rs:WP_027477969	DNA topoisomerase III [Curvibacter gracilis].	65.13	433	138	4	29	459	237	658	0.0	548
rs:WP_031943161	TraE DNA topoisomerase [uncultured bacterium].	58.06	484	147	6	29	459	244	724	0.0	548
rs:WP_011544434	TraE DNA topoisomerase [uncultured bacterium].	58.06	484	147	6	29	459	244	724	0.0	548
tr:S6JIF2_PSEST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	58.06	484	147	6	29	459	244	724	0.0	547
rs:WP_015445012	DNA topoisomerase [Legionella pneumophila].	58.09	439	179	2	21	459	237	670	0.0	538
rs:WP_033557767	DNA topoisomerase [Escherichia coli].	59.67	429	166	3	30	458	245	666	0.0	535
rs:WP_040107074	DNA topoisomerase [Azotobacter chroococcum].	55.67	485	157	4	29	459	244	724	0.0	536
rs:WP_034284084	DNA topoisomerase, partial [Aeromonas salmonicida].	59.07	430	168	3	29	458	8	429	0.0	525
rs:WP_033811278	DNA topoisomerase [Escherichia coli].	58.84	430	170	3	29	458	244	666	2e-180	533
rs:WP_019842061	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	58.84	430	170	3	29	458	244	666	2e-180	533
rs:WP_001263214	MULTISPECIES: DNA topoisomerase [Enterobacteriaceae].	58.84	430	170	3	29	458	244	666	2e-180	533
tr:A0A0C5PJ08_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	59.07	430	168	3	29	458	244	665	3e-180	533
rs:WP_023363291	DNA topoisomerase III [Escherichia coli].	59.30	430	167	3	29	458	244	665	3e-180	532
rs:WP_015059025	hypothetical protein [Escherichia coli].	59.07	430	168	3	29	458	244	665	4e-180	532
rs:WP_004196257	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	59.30	430	167	3	29	458	244	665	4e-180	532
rs:WP_024252942	DNA topoisomerase [Escherichia coli].	59.07	430	168	3	29	458	244	665	4e-180	532
rs:WP_039696268	DNA topoisomerase [Enterobacter cloacae].	59.30	430	167	3	29	458	244	665	5e-180	532
rs:WP_032310187	DNA topoisomerase [Escherichia coli].	59.07	430	168	3	29	458	244	665	5e-180	532
rs:WP_048269926	DNA topoisomerase [Klebsiella pneumoniae].	59.07	430	168	3	29	458	244	665	5e-180	532
rs:WP_032141116	DNA topoisomerase [Escherichia coli].	59.07	430	168	3	29	458	244	665	6e-180	531
rs:WP_003019763	MULTISPECIES: hypothetical protein [Enterobacteriaceae].	59.30	430	167	3	29	458	244	665	1e-179	531
gpu:KM655310_2	putative DNA topoisomerase [uncultured bacterium]	86.33	278	37	1	182	459	1	277	4e-178	513
rs:WP_031943421	conjugal transfer protein TraF [uncultured bacterium].	59.21	429	167	3	30	458	245	665	2e-177	525
rs:WP_037005304	DNA topoisomerase, partial [Pseudomonas stutzeri].	66.14	381	125	3	29	408	244	621	9e-174	514
rs:WP_036247157	DNA topoisomerase, partial [Methylobacter sp. BBA5.1].	79.05	296	61	1	56	351	4	298	8e-172	497
rs:WP_011988435	DNA topoisomerase [Yersinia pseudotuberculosis].	53.60	431	193	2	29	459	248	671	8e-166	496
rs:WP_000596661	hypothetical protein, partial [Shigella boydii].	58.35	389	153	3	70	458	1	380	3e-165	484
rs:WP_034382965	DNA topoisomerase, partial [Comamonas testosteroni].	55.43	433	183	3	30	459	246	671	3e-161	486
tr:A0A0E3BE52_COMTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	55.43	433	183	3	30	459	244	669	3e-161	486
tr:I6F131_SHIBO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	58.29	362	142	3	97	458	1	353	3e-153	452
rs:WP_028386518	DNA topoisomerase [Legionella geestiana].	50.23	444	209	3	16	459	222	653	2e-152	461
rs:WP_036295630	DNA topoisomerase, partial [Methylobacter whittenburyi].	73.31	296	39	1	56	351	4	259	1e-150	441
rs:WP_031578390	DNA topoisomerase [Ruminobacter sp. RM87].	49.88	425	210	3	36	459	248	670	2e-146	446
rs:WP_033480338	DNA topoisomerase, partial [Xanthomonas axonopodis].	50.92	436	199	7	30	458	175	602	9e-136	416
rs:WP_017170279	hypothetical protein, partial [Xanthomonas axonopodis].	50.92	436	199	7	30	458	172	599	1e-134	415
rs:WP_017161576	hypothetical protein [Xanthomonas axonopodis].	50.92	436	199	7	30	458	237	664	1e-133	414
rs:WP_005430340	DNA topoisomerase [Sutterella wadsworthensis].	52.15	372	170	4	29	398	246	611	5e-121	378
rs:WP_008812062	DNA topoisomerase III [Burkholderiales bacterium 1_1_47].	49.73	374	182	3	30	401	247	616	1e-115	365
rs:WP_038036807	DNA topoisomerase III [Thioalkalivibrio sp. ALE20].	44.96	427	215	5	36	459	206	615	2e-115	367
rs:WP_008864255	DNA topoisomerase III [Parasutterella excrementihominis].	45.68	370	195	2	31	399	249	613	4e-110	350
rs:WP_040603635	DNA topoisomerase [Parasutterella excrementihominis].	45.78	367	189	3	32	397	250	607	7e-107	342
rs:WP_036293217	hypothetical protein [Methylobacter whittenburyi].	45.37	432	218	8	31	459	237	653	8e-107	343
tr:F3QN10_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	45.78	367	189	3	32	397	252	609	8e-107	342
rs:WP_038141933	DNA topoisomerase III [Thiothrix lacustris].	43.54	441	221	6	34	450	246	682	1e-105	340
rs:WP_028389303	hypothetical protein [Legionella fairfieldensis].	40.61	426	243	4	35	459	241	657	1e-104	337
rs:WP_008253114	DNA topoisomerase III [Limnobacter sp. MED105].	45.08	437	214	10	31	459	244	662	2e-104	337
rs:WP_027889424	DNA topoisomerase [Megamonas hypermegale].	42.70	445	226	9	29	459	237	666	2e-104	340
rs:WP_037592209	DNA topoisomerase, partial [Sporomusa ovata].	42.59	432	227	9	29	455	237	652	4e-104	336
tr:T0JN21_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	42.59	432	227	9	29	455	237	652	6e-104	336
rs:WP_018168697	hypothetical protein, partial [Thioalkalivibrio sp. ALMg9].	41.78	426	234	6	36	459	208	621	8e-104	337
rs:WP_018158381	hypothetical protein, partial [Thioalkalivibrio sp. ALE14].	42.02	426	233	6	36	459	208	621	1e-103	336
rs:WP_019568985	hypothetical protein, partial [Thioalkalivibrio sp. ALMg13-2].	42.02	426	233	6	36	459	208	621	2e-103	335
rs:WP_017926600	hypothetical protein, partial [Thioalkalivibrio sp. HL-Eb18].	42.02	426	233	6	36	459	208	621	2e-103	335
rs:WP_018878671	hypothetical protein, partial [Thioalkalivibrio sp. ALE28].	42.02	426	233	6	36	459	208	621	2e-103	335
rs:WP_018948401	hypothetical protein, partial [Thioalkalivibrio sp. ALMg11].	41.78	426	234	6	36	459	208	621	6e-103	334
rs:WP_007958677	DNA topoisomerase III [Pelosinus fermentans].	43.78	434	227	8	29	459	237	656	1e-102	332
rs:WP_006305756	DNA topoisomerase TopB [Centipeda periodontii].	43.22	435	231	6	30	459	241	664	2e-102	333
rs:WP_029435132	DNA topoisomerase III [Bilophila wadsworthia].	41.63	430	234	6	30	459	238	650	2e-102	334
rs:WP_019559093	hypothetical protein, partial [Thioalkalivibrio sp. ALE12].	41.45	427	234	6	36	459	208	621	3e-102	332
rs:WP_017941455	hypothetical protein, partial [Thioalkalivibrio sp. ALE6].	41.22	427	235	6	36	459	208	621	3e-102	332
rs:WP_018999978	DNA topoisomerase III [Megamonas rupellensis].	40.63	443	240	7	29	459	237	668	7e-102	333
rs:WP_019584476	hypothetical protein, partial [Thioalkalivibrio sp. ALE16].	40.98	427	236	6	36	459	208	621	9e-102	331
rs:WP_011171725	DNA topoisomerase III [Achromobacter denitrificans].	39.56	498	241	8	19	459	228	722	2e-101	331
rs:WP_008538783	DNA topoisomerase III [Megamonas funiformis].	40.63	443	240	7	29	459	237	668	2e-101	332
rs:WP_018873968	MULTISPECIES: hypothetical protein [Thioalkalivibrio].	40.75	427	237	6	36	459	206	619	2e-101	330
rs:WP_046977534	conjugal transfer protein TraE [Xanthomonas hyacinthi].	39.56	498	241	8	19	459	228	722	3e-101	330
rs:WP_011205815	MULTISPECIES: DNA topoisomerase [Proteobacteria].	39.29	481	234	5	35	459	246	724	3e-101	330
rs:WP_031944022	TraE conjugative transfer protein, DNA topoisomerase [uncultured bacterium pAKD4].	39.56	498	241	8	19	459	228	722	3e-101	330
rs:WP_027406931	DNA topoisomerase [Anaerovibrio sp. RM50].	42.86	441	233	8	32	459	241	675	3e-101	333
rs:WP_007938669	MULTISPECIES: DNA topoisomerase III [Pelosinus].	43.32	434	229	8	29	459	237	656	4e-101	328
rs:WP_018879179	hypothetical protein, partial [Thioalkalivibrio sp. ALE9].	40.98	427	236	6	36	459	208	621	5e-101	329
rs:WP_015063531	TraE Conjugative transfer protein, DNA topoisomerase [Burkholderia cepacia].	39.36	498	242	8	19	459	228	722	5e-101	330
rs:WP_019552090	hypothetical protein [Propionispira raffinosivorans].	42.33	437	231	8	29	459	237	658	9e-101	330
tr:W1EZD8_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	59.77	256	100	1	29	284	244	496	1e-100	322
rs:WP_046797616	conjugal transfer protein TraE [Rhizobium sp. LC145].	38.88	481	236	5	35	459	246	724	1e-100	329
rs:WP_042825712	conjugal transfer protein TraE [Xanthomonas axonopodis].	37.92	480	243	2	35	459	243	722	2e-100	328
rs:WP_039445299	conjugal transfer protein TraE [Xanthomonas vasicola].	37.92	480	243	2	35	459	243	722	2e-100	328
rs:WP_022227915	DNA topoisomerase [Megamonas funiformis CAG:377].	40.18	443	242	7	29	459	237	668	2e-100	329
rs:WP_012824474	DNA topoisomerase III [Halothiobacillus neapolitanus].	41.26	429	233	6	36	459	240	654	3e-100	327
rs:WP_026296468	DNA topoisomerase III, partial [Thioalkalivibrio sp. ALJ2].	40.52	427	238	6	36	459	208	621	3e-100	327
rs:WP_020565900	hypothetical protein [Methylosarcina fibrata].	37.37	495	255	4	19	459	226	719	4e-100	327
rs:WP_031943130	DNA processing protein [uncultured bacterium].	39.09	481	235	5	35	459	246	724	4e-100	327
rs:WP_037353282	DNA topoisomerase [Selenomonas sp. FC4001].	40.14	441	243	7	29	459	238	667	6e-100	329
rs:WP_039207770	DNA topoisomerase [Anaerovibrio lipolyticus].	41.89	444	239	8	29	459	238	675	8e-100	329
rs:WP_027397710	DNA topoisomerase [Anaerovibrio lipolyticus].	41.95	441	237	8	32	459	241	675	8e-100	329
rs:WP_009754085	DNA topoisomerase TopB [Selenomonas sp. oral taxon 149].	43.58	436	228	8	30	459	240	663	1e-99	326
rs:WP_021771516	DNA topoisomerase [Mitsuokella sp. oral taxon 131].	41.88	437	236	7	29	458	238	663	2e-99	328
rs:WP_013333796	DNA topoisomerase III [Halomonas elongata].	41.87	418	234	5	35	450	242	652	3e-99	323
rs:WP_040292887	DNA topoisomerase, partial [Acetonema longum].	42.53	435	230	7	30	459	238	657	4e-99	323
rs:WP_037364060	DNA topoisomerase, partial [Selenomonas ruminantium].	39.49	433	245	6	30	459	239	657	6e-99	322
rs:WP_009440429	DNA topoisomerase [Selenomonas sp. oral taxon 138].	42.07	435	236	6	30	459	241	664	6e-99	324
tr:F7NGY8_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	42.53	435	230	7	30	459	238	657	2e-98	323
rs:WP_016418561	hypothetical protein [Halomonas anticariensis].	40.28	427	237	4	31	450	238	653	3e-98	321
rs:WP_028129876	DNA topoisomerase [Selenomonas sp. AE3005].	40.63	443	238	8	29	459	238	667	3e-98	325
rs:WP_035474305	DNA topoisomerase III [Gammaproteobacteria bacterium MFB021].	39.48	423	245	4	35	454	242	656	3e-98	321
rs:WP_026759425	DNA topoisomerase [Selenomonas ruminantium].	40.05	437	241	7	33	459	242	667	4e-98	325
rs:WP_000419478	hypothetical protein, partial [Salmonella enterica].	41.83	416	228	6	36	450	32	434	6e-98	313
rs:WP_013745196	DNA topoisomerase III [Gallibacterium anatis].	41.04	424	228	8	29	449	232	636	7e-98	319
rs:WP_026766366	DNA topoisomerase [Selenomonas ruminantium].	40.14	441	243	7	29	459	238	667	8e-98	323
rs:WP_039148623	DNA topoisomerase III [Gallibacterium anatis].	41.04	424	228	7	29	449	232	636	1e-97	319
rs:WP_035921612	hypothetical protein, partial [Legionella moravica].	39.62	419	246	3	36	453	241	653	1e-97	319
rs:WP_047643156	DNA topoisomerase III [Salmonella enterica].	42.36	432	226	8	36	459	242	658	2e-97	319
rs:WP_022373687	DNA topoisomerase III [Sutterella sp. CAG:397].	43.49	384	208	3	29	403	248	631	2e-97	318
tr:G5QPK6_SALRU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	42.93	417	221	7	36	450	242	643	3e-97	318
rs:WP_018347287	MULTISPECIES: DNA topoisomerase III [Gallibacterium].	40.80	424	229	7	29	449	232	636	3e-97	318
rs:WP_039145124	DNA topoisomerase III [Gallibacterium anatis].	40.80	424	229	8	29	449	232	636	4e-97	317
rs:WP_039089672	DNA topoisomerase III [Gallibacterium anatis].	40.80	424	229	8	29	449	232	636	4e-97	317
rs:WP_039081120	DNA topoisomerase III [Gallibacterium anatis].	40.80	424	229	7	29	449	232	636	4e-97	317
rs:WP_039158592	DNA topoisomerase III [Gallibacterium anatis].	40.80	424	229	7	29	449	232	636	4e-97	317
rs:WP_038674145	DNA topoisomerase [Pelosinus sp. UFO1].	41.71	434	236	7	29	459	237	656	4e-97	317
rs:WP_023240864	DNA topoisomerase III [Salmonella enterica].	42.36	432	226	8	36	459	242	658	5e-97	318
rs:WP_005577632	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	40.62	416	232	5	36	449	244	646	5e-97	318
rs:WP_017169014	hypothetical protein, partial [Xanthomonas axonopodis].	50.77	325	145	7	141	458	3	319	1e-96	307
rs:WP_021817730	hypothetical protein [Halomonas huangheensis].	40.33	424	237	6	35	452	242	655	1e-96	317
rs:WP_026762718	DNA topoisomerase [Selenomonas artemidis].	42.08	442	225	8	30	458	241	664	2e-96	317
rs:WP_024153970	DNA topoisomerase III [Salmonella enterica].	41.94	422	228	6	36	455	242	648	3e-96	316
rs:WP_017168549	hypothetical protein, partial [Xanthomonas axonopodis].	50.77	325	145	7	141	458	1	317	3e-96	306
rs:WP_037372006	DNA topoisomerase, partial [Selenomonas sp. AE3005].	39.03	433	247	6	30	459	239	657	3e-96	315
rs:WP_015606321	DNA topoisomerase III [Salmonella enterica].	42.07	416	227	6	36	450	242	644	4e-96	315
rs:WP_041189026	DNA topoisomerase [Burkholderia pseudomallei].	40.27	442	245	8	29	459	261	694	6e-96	316
rs:WP_035415424	DNA topoisomerase III [Chromohalobacter israelensis].	38.79	428	250	4	31	454	238	657	7e-96	315
tr:F2Q8P5_SALEE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	42.45	417	223	7	36	450	242	643	7e-96	315
rs:WP_006696787	hypothetical protein [Selenomonas noxia].	42.76	435	233	7	30	459	241	664	7e-96	316
rs:WP_020485826	hypothetical protein [Methylomonas sp. MK1].	37.63	481	242	5	35	459	241	719	8e-96	316
rs:WP_045036739	DNA topoisomerase III [Photobacterium iliopiscarium].	39.14	465	232	8	36	459	240	694	9e-96	315
rs:WP_006693725	DNA topoisomerase TopB [Selenomonas noxia].	42.53	435	234	7	30	459	241	664	1e-95	315
rs:WP_040289620	DNA topoisomerase III, partial [Bilophila wadsworthia].	41.11	416	230	6	30	445	237	637	1e-95	313
rs:WP_009350711	DNA topoisomerase [Selenomonas artemidis].	41.43	449	226	9	30	459	241	671	1e-95	315
rs:WP_027962007	DNA topoisomerase III [Halomonas halodenitrificans].	41.53	419	225	6	36	450	242	644	1e-95	313
rs:WP_006693315	hypothetical protein [Selenomonas infelix].	43.22	435	230	8	30	459	241	663	2e-95	315
tr:F2Q883_SALBN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	41.83	416	228	6	36	450	242	644	2e-95	313
rs:WP_023226745	DNA topoisomerase III [Salmonella enterica].	41.83	416	228	6	36	450	242	644	2e-95	313
rs:WP_036204086	DNA topoisomerase [Megasphaera elsdenii].	42.09	430	228	10	29	454	239	651	2e-95	315
rs:WP_009657658	DNA topoisomerase III [Selenomonas sp. FOBRC9].	41.65	449	225	9	30	459	241	671	2e-95	315
rs:WP_001241572	DNA topoisomerase III [Salmonella enterica].	41.83	416	228	6	36	450	242	644	2e-95	313
rs:WP_009655052	DNA topoisomerase III [Selenomonas sp. FOBRC6].	42.99	435	231	8	30	459	241	663	2e-95	314
rs:WP_036378381	DNA topoisomerase [Mitsuokella jalaludinii].	39.64	444	244	7	29	459	238	670	2e-95	317
tr:E5Y702_BILWA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	40.70	430	239	7	30	459	237	650	3e-95	316
rs:WP_037376986	DNA topoisomerase, partial [Selenomonas ruminantium].	38.28	418	242	4	30	445	239	642	3e-95	312
rs:WP_045494938	DNA topoisomerase III [Vibrio sp. 151112A].	38.69	473	237	9	36	459	236	704	3e-95	314
rs:WP_014620938	DNA topoisomerase III [Shewanella baltica].	39.14	465	235	8	36	459	239	696	3e-95	314
rs:WP_019053936	conjugal transfer protein TraE [Sphingobium xenophagum].	38.76	498	245	8	19	459	223	717	3e-95	314
rs:WP_041197081	DNA topoisomerase [Burkholderia pseudomallei].	39.82	442	247	8	29	459	261	694	5e-95	313
rs:WP_001241569	DNA topoisomerase III [Salmonella enterica].	41.59	416	229	6	36	450	242	644	5e-95	312
rs:WP_039977192	DNA topoisomerase III [Vibrio jasicida].	40.88	433	237	8	36	459	237	659	6e-95	313
rs:WP_038114435	DNA topoisomerase [Veillonella sp. AS16].	40.25	477	241	12	19	454	230	703	6e-95	315
rs:WP_006691043	DNA topoisomerase [Selenomonas flueggei].	43.12	436	230	8	30	459	240	663	8e-95	313
rs:WP_006954185	DNA topoisomerase III [Sphingobium japonicum].	38.76	498	245	8	19	459	223	717	1e-94	313
rs:WP_014016907	DNA topoisomerase [Megasphaera elsdenii].	41.86	430	229	10	29	454	239	651	1e-94	312
rs:WP_011839989	DNA topoisomerase III [Shewanella baltica].	38.92	465	236	8	36	459	239	696	1e-94	312
rs:WP_027895674	DNA topoisomerase [Megasphaera elsdenii].	41.86	430	229	10	29	454	239	651	1e-94	312
rs:WP_014620441	DNA topoisomerase III [Shewanella baltica].	38.92	465	236	8	36	459	239	696	2e-94	312
rs:WP_006691865	topoisomerase III [Selenomonas infelix].	39.05	443	250	8	23	459	232	660	2e-94	313
rs:WP_020311399	MULTISPECIES: DNA topoisomerase [Megasphaera].	40.70	430	234	8	29	454	239	651	2e-94	312
rs:WP_009645530	DNA topoisomerase III [Selenomonas sp. CM52].	40.41	443	240	8	29	459	238	668	2e-94	313
rs:WP_044349383	DNA topoisomerase III [Raoultella ornithinolytica].	41.20	415	231	6	36	449	242	644	2e-94	310
rs:WP_029541017	DNA topoisomerase [Selenomonas ruminantium].	40.50	442	240	8	29	459	238	667	3e-94	314
rs:WP_012340838	MULTISPECIES: DNA topoisomerase III [Pasteurellaceae].	38.50	426	245	7	35	457	244	655	4e-94	310
rs:WP_024799102	DNA topoisomerase III [Salmonella enterica].	41.35	416	230	6	36	450	242	644	4e-94	310
rs:WP_021772031	DNA topoisomerase [Mitsuokella sp. oral taxon 131].	39.72	428	240	5	34	459	242	653	4e-94	310
rs:WP_009114262	DNA topoisomerase III [Brenneria sp. EniD312].	40.77	417	234	5	36	450	242	647	4e-94	310
rs:WP_031586293	DNA topoisomerase [Selenomonas bovis].	41.40	442	231	9	33	459	242	670	5e-94	314
rs:WP_042988804	hypothetical protein [Vibrio cholerae].	37.67	438	255	5	31	459	237	665	5e-94	311
tr:W0QQA8_9PAST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	38.50	426	245	7	35	457	263	674	6e-94	310
rs:WP_029642229	DNA topoisomerase III, partial [Acinetobacter baumannii].	37.79	434	257	5	36	459	75	505	7e-94	305
tr:T0XU08_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	40.94	425	233	9	27	451	69	475	8e-94	305
rs:WP_004856680	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	40.72	415	233	6	36	449	242	644	8e-94	309
rs:WP_041154757	DNA topoisomerase III [Vibrio mytili].	38.48	434	254	5	36	459	242	672	8e-94	311
rs:WP_037350384	DNA topoisomerase, partial [Selenomonas sp. oral taxon 137].	40.39	463	239	9	16	459	227	671	8e-94	310
rs:WP_017085213	DNA topoisomerase III [Vibrio splendidus].	38.48	434	254	5	36	459	242	672	8e-94	311
tr:F0V072_SALBN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	41.97	417	225	7	36	450	242	643	9e-94	309
tr:A0A0A5N0V8_SERMA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	41.97	417	231	5	36	450	242	649	1e-93	309
rs:WP_014726311	DNA topoisomerase [Burkholderia sp. KJ006].	40.18	448	241	9	29	459	251	688	1e-93	310
rs:WP_038007810	DNA topoisomerase, partial [Sutterella wadsworthensis].	43.91	394	205	4	31	408	245	638	1e-93	308
rs:WP_038397646	DNA topoisomerase III [Salmonella enterica].	40.87	416	231	7	36	449	242	644	1e-93	308
rs:WP_035234763	DNA topoisomerase III [Alcanivorax sp. 19-m-6].	39.09	440	243	9	36	459	242	672	2e-93	310
rs:WP_022497972	DNA topoisomerase [Megasphaera elsdenii CAG:570].	41.63	430	230	10	29	454	239	651	2e-93	310
rs:WP_038729615	DNA topoisomerase [Burkholderia sp. ABCPW 1].	39.37	442	249	8	29	459	261	694	2e-93	309
rs:WP_006248877	DNA topoisomerase III [Mannheimia haemolytica].	38.35	425	247	6	35	457	244	655	2e-93	308
rs:WP_017879692	hypothetical protein [Janthinobacterium sp. CG3].	37.42	497	253	7	19	459	228	722	2e-93	310
rs:WP_012766322	MULTISPECIES: DNA topoisomerase 3 (DNA topoisomerase III) [Gammaproteobacteria].	38.71	434	253	5	36	459	242	672	2e-93	310
rs:WP_046224208	DNA topoisomerase III [Vibrio sp. ECSMB14106].	38.48	434	254	5	36	459	242	672	2e-93	310
rs:WP_027912503	DNA topoisomerase III [Pseudomonas sp. URIL14HWK12:I7].	39.91	426	238	7	36	458	241	651	2e-93	308
tr:K1JUJ7_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	43.91	394	205	4	31	408	245	638	3e-93	308
rs:WP_014386700	MULTISPECIES: DNA topoisomerase III [Vibrionaceae].	38.48	434	254	5	36	459	242	672	3e-93	309
rs:WP_021684478	DNA topoisomerase [Selenomonas sp. oral taxon 892].	41.38	435	239	7	30	459	241	664	3e-93	309
rs:WP_023157825	DNA topoisomerase [Klebsiella pneumoniae].	40.62	416	232	7	36	449	242	644	3e-93	308
rs:WP_034164950	DNA topoisomerase III [Edwardsiella tarda].	37.56	434	258	6	36	459	242	672	4e-93	309
rs:WP_043143773	DNA topoisomerase III [Serratia marcescens].	41.73	417	232	5	36	450	242	649	4e-93	307
rs:WP_039272426	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	38.48	434	254	5	36	459	242	672	5e-93	308
rs:WP_047609561	DNA topoisomerase III, partial [Escherichia coli].	37.56	434	258	5	36	459	50	480	5e-93	303
rs:WP_005607796	MULTISPECIES: DNA topoisomerase III [Actinobacillus].	39.81	422	239	7	35	455	244	651	6e-93	307
rs:WP_001241570	DNA topoisomerase III [Salmonella enterica].	41.94	422	228	6	36	455	242	648	7e-93	307
rs:WP_014338762	DNA topoisomerase III [Pseudomonas fluorescens].	38.88	427	247	6	33	458	239	652	8e-93	306
rs:WP_000463492	DNA topoisomerase III, partial [Salmonella enterica].	37.56	434	258	5	36	459	75	505	9e-93	303
tr:D4M8T1_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	38.83	443	252	7	29	459	238	673	1e-92	306
rs:WP_006253622	DNA topoisomerase III [Mannheimia haemolytica].	38.12	425	248	6	35	457	244	655	1e-92	306
rs:WP_039195103	DNA topoisomerase III [Actinobacillus suis].	39.81	422	239	7	35	455	244	651	1e-92	306
rs:WP_021117221	DNA topoisomerase III family protein [[Haemophilus] parasuis].	38.26	426	246	7	35	457	244	655	2e-92	306
rs:WP_009728377	DNA topoisomerase III [Selenomonas sp. F0473].	42.92	438	227	9	30	458	241	664	2e-92	307
rs:WP_005841157	DNA topoisomerase III [Mitsuokella multacida].	39.68	441	245	7	29	459	238	667	2e-92	309
tr:C9LYN3_SELS3	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	40.09	444	240	8	29	459	228	658	2e-92	307
rs:WP_013741022	DNA topoisomerase III [Selenomonas sputigena].	40.09	444	240	8	29	459	238	668	2e-92	307
rs:WP_000765275	DNA topoisomerase III [Escherichia coli].	40.09	424	231	8	32	449	238	644	2e-92	305
rs:WP_024153900	DNA topoisomerase III [Salmonella enterica].	41.94	422	228	6	36	455	242	648	2e-92	305
rs:WP_034949922	DNA topoisomerase III, partial [Erwinia oleae].	41.20	415	233	5	36	448	242	647	2e-92	305
rs:WP_044143582	hypothetical protein, partial [Succinimonas amylolytica].	44.50	373	194	5	30	399	240	602	3e-92	303
rs:WP_021147943	DNA topoisomerase III [Veillonella parvula].	39.33	478	243	12	19	454	230	702	3e-92	308
rs:WP_020001908	hypothetical protein [Desulfovibrio desulfuricans].	40.93	430	221	8	30	457	237	635	3e-92	306
rs:WP_042852207	DNA topoisomerase III [Escherichia coli].	37.85	428	257	4	36	459	242	664	3e-92	306
rs:WP_047663111	DNA topoisomerase III, partial [Escherichia coli].	37.56	434	258	5	36	459	144	574	5e-92	303
rs:WP_008600558	DNA topoisomerase III [Veillonella sp. 6_1_27].	39.12	478	244	12	19	454	230	702	5e-92	307
rs:WP_036813091	DNA topoisomerase III [Photorhabdus luminescens].	38.25	434	255	5	36	459	242	672	5e-92	306
rs:WP_019542902	hypothetical protein [Selenomonas bovis].	39.30	430	246	6	34	459	247	665	5e-92	305
rs:WP_000765276	DNA topoisomerase III [Salmonella enterica].	40.38	416	233	7	36	449	242	644	6e-92	304
rs:WP_012864143	DNA topoisomerase III [Veillonella parvula].	39.33	478	243	12	19	454	230	702	6e-92	306
rs:WP_000366824	DNA topoisomerase III [Salmonella enterica].	38.25	434	255	5	36	459	242	672	7e-92	306
rs:WP_023218679	DNA topoisomerase III [Salmonella enterica].	40.62	416	232	7	36	449	242	644	7e-92	304
rs:WP_004697350	DNA topoisomerase [Veillonella parvula].	39.12	478	244	12	19	454	230	702	7e-92	306
rs:WP_040975693	DNA topoisomerase III [Pasteurella sp. FF6].	40.99	383	211	5	69	451	278	645	8e-92	304
tr:C6HTV9_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	40.18	438	244	8	14	451	226	645	9e-92	304
tr:G9EQA5_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	37.70	427	252	5	36	458	241	657	1e-91	304
tr:W1DKN2_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	37.79	434	257	5	36	459	184	614	1e-91	303
rs:WP_006556936	DNA topoisomerase III [Veillonella ratti].	37.78	487	240	9	29	454	239	723	1e-91	307
rs:WP_019002781	hypothetical protein [Succinimonas amylolytica].	41.39	418	223	8	30	443	241	640	1e-91	305
rs:WP_039588664	DNA topoisomerase III [Pseudomonas frederiksbergensis].	39.16	429	243	7	33	458	238	651	1e-91	303
rs:WP_005687564	DNA topoisomerase III [Haemophilus influenzae].	40.99	383	211	5	69	451	278	645	1e-91	303
rs:WP_040536140	hypothetical protein, partial [Legionella drancourtii].	37.97	424	253	4	36	458	208	622	2e-91	302
rs:WP_014423558	DNA topoisomerase 3 [Selenomonas ruminantium].	39.00	441	248	7	29	459	238	667	2e-91	307
rs:WP_023043374	DNA topoisomerase III, partial [Photorhabdus temperata].	37.79	434	257	5	36	459	217	647	2e-91	304
tr:T0XPW2_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	42.38	420	219	11	34	445	142	546	2e-91	301
rs:WP_047882647	DNA topoisomerase III [Pseudomonas sp. ARP3].	39.11	427	246	6	33	458	238	651	2e-91	303
rs:WP_047542282	DNA topoisomerase III [Pseudomonas simiae].	38.88	427	247	6	33	458	239	652	2e-91	303
rs:WP_036845149	DNA topoisomerase III [Photorhabdus temperata].	37.79	434	257	5	36	459	242	672	2e-91	305
rs:WP_040841233	DNA topoisomerase III, partial [Thiothrix nivea].	43.90	369	203	2	34	398	247	615	2e-91	301
rs:WP_005387096	hypothetical protein [Veillonella dispar].	39.50	476	245	12	19	454	230	702	2e-91	305
tr:I3BZ80_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	43.55	372	206	2	34	401	258	629	2e-91	302
rs:WP_047922031	DNA topoisomerase III [Pasteurella multocida].	40.99	383	211	5	69	451	278	645	2e-91	303
tr:W1W322_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	39.50	476	245	12	19	454	230	702	2e-91	305
rs:WP_009351396	DNA topoisomerase [Veillonella sp. oral taxon 158].	39.83	477	242	13	19	454	230	702	2e-91	305
rs:WP_004693293	DNA topoisomerase [Veillonella parvula].	39.12	478	244	12	19	454	230	702	3e-91	305
tr:G9ESR0_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	37.97	424	253	4	36	458	241	655	3e-91	302
rs:WP_048514732	DNA topoisomerase [Megasphaera cerevisiae].	41.63	430	230	8	29	454	237	649	4e-91	303
rs:WP_012564926	DNA topoisomerase III [Haemophilus influenzae].	40.73	383	212	5	69	451	278	645	4e-91	302
rs:WP_039163724	DNA topoisomerase III [Gallibacterium anatis].	39.71	418	231	8	36	450	245	644	5e-91	302
tr:E4LK90_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	40.39	463	239	9	16	459	227	671	5e-91	310
tr:E6QBD0_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CBI04506.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI04506.1};	44.44	414	206	11	15	417	234	634	6e-91	301
rs:WP_032438011	DNA topoisomerase III [Klebsiella pneumoniae].	37.56	434	258	5	36	459	242	672	6e-91	303
rs:WP_034022901	DNA topoisomerase [Pseudomonas aeruginosa].	38.86	458	239	10	31	452	259	711	6e-91	303
rs:WP_000366819	DNA topoisomerase III [Vibrio mimicus].	37.79	434	257	5	36	459	242	672	6e-91	303
rs:WP_029308519	DNA topoisomerase [Cupriavidus metallidurans].	39.19	467	239	11	32	458	259	720	6e-91	303
rs:WP_044269281	DNA topoisomerase III [Pseudomonas fluorescens].	37.88	433	255	6	23	454	228	647	6e-91	301
rs:WP_000366823	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	37.56	434	258	5	36	459	242	672	6e-91	303
rs:WP_000366821	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	37.79	434	257	5	36	459	242	672	6e-91	303
rs:WP_010845928	DNA topoisomerase [Xenorhabdus nematophila].	37.56	434	258	5	36	459	242	672	7e-91	303
rs:WP_041021229	DNA topoisomerase III [Pseudomonas sp. SHC52].	39.06	425	241	7	33	454	238	647	7e-91	301
rs:WP_000366822	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	37.79	434	257	5	36	459	242	672	7e-91	303
rs:WP_014326561	DNA topoisomerase III [Haemophilus influenzae].	40.73	383	212	5	69	451	278	645	7e-91	302
rs:WP_040535462	hypothetical protein, partial [Legionella drancourtii].	37.95	419	246	5	36	450	241	649	7e-91	301
gpu:KR091911_144	DNA topoisomerase III [Salmonella enterica subsp. enterica serovar Corvallis]	37.56	434	258	5	36	459	250	680	8e-91	303
rs:WP_041982297	DNA topoisomerase III [Xenorhabdus nematophila].	37.56	434	258	5	36	459	242	672	8e-91	303
tr:Q4QPE8_HAEI8	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	40.73	383	212	5	69	451	283	650	9e-91	301
rs:WP_042907306	DNA topoisomerase III [Gallibacterium anatis].	38.76	418	235	7	36	450	245	644	9e-91	301
rs:WP_014064994	DNA topoisomerase III [Haemophilus parainfluenzae].	40.73	383	212	5	69	451	278	645	1e-90	301
rs:WP_037319066	hypothetical protein, partial [Ruminobacter sp. RM87].	43.56	365	198	3	34	398	246	602	1e-90	299
rs:WP_013141536	DNA topoisomerase III [Xenorhabdus nematophila].	37.84	436	254	6	36	459	242	672	1e-90	302
rs:WP_023135508	DNA topoisomerase III [Salmonella enterica].	40.87	416	232	6	36	450	242	644	1e-90	301
rs:WP_048392842	DNA topoisomerase III [Pseudomonas lini].	39.01	423	244	6	33	454	238	647	1e-90	300
tr:A0A088SE88_SALCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	37.56	434	258	5	36	459	242	672	1e-90	302
rs:WP_024126915	hypothetical protein [Vibrio cholerae].	37.56	434	258	5	36	459	242	672	2e-90	302
rs:WP_011872847	DNA topoisomerase III [Yersinia ruckeri].	37.79	434	257	5	36	459	242	672	2e-90	302
tr:A0LAP8_MAGSM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	38.34	446	242	5	36	454	241	680	2e-90	302
rs:WP_033567093	DNA topoisomerase III [Salmonella enterica].	41.49	417	231	7	36	449	242	648	2e-90	300
rs:WP_043307593	DNA topoisomerase III [Burkholderia glumae].	39.96	448	241	11	27	452	267	708	2e-90	301
rs:WP_034103292	DNA topoisomerase III [Pseudomonas fluorescens].	38.53	423	246	6	33	454	238	647	2e-90	300
rs:WP_011145395	DNA topoisomerase III [Photorhabdus luminescens].	39.44	426	246	6	36	459	242	657	2e-90	300
tr:C5A9D2_BURGB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	39.96	448	241	11	27	452	277	718	2e-90	301
rs:WP_021598073	DNA topoisomerase III protein TopB [Escherichia coli].	37.56	434	258	5	36	459	242	672	3e-90	301
rs:WP_025214466	DNA topoisomerase III [Pseudomonas brassicacearum].	38.64	427	248	6	33	458	239	652	3e-90	300
rs:WP_022542388	DNA topoisomerase III [Salmonella enterica].	37.79	434	257	5	36	459	242	672	3e-90	301
rs:WP_005667784	DNA topoisomerase III [Haemophilus influenzae].	40.47	383	213	5	69	451	278	645	3e-90	300
rs:WP_005653577	DNA topoisomerase III [Haemophilus influenzae].	40.47	383	213	5	69	451	278	645	3e-90	300
rs:WP_038220216	DNA topoisomerase III [Xenorhabdus nematophila].	37.56	434	258	5	36	459	242	672	4e-90	301
gpu:KP795541_3	DNA topoisomerase III [Vibrio tasmaniensis]	38.76	436	252	7	29	459	229	654	4e-90	300
rs:WP_013184415	DNA topoisomerase III [Xenorhabdus nematophila].	37.61	436	255	6	36	459	242	672	4e-90	301
gpu:CP011223_697	DNA topoisomerase III [[Haemophilus] ducreyi]	40.47	383	213	5	69	451	278	645	4e-90	300
rs:WP_020334544	DNA topoisomerase III [Vibrio natriegens].	41.19	369	210	1	36	404	255	616	4e-90	299
rs:WP_023100649	hypothetical protein [Pseudomonas aeruginosa].	38.51	457	242	9	31	452	259	711	5e-90	300
rs:WP_026045081	DNA topoisomerase [Burkholderia pyrrocinia].	38.58	438	244	8	30	458	249	670	6e-90	300
rs:WP_042906600	DNA topoisomerase III, partial [[Haemophilus] parasuis].	40.67	418	230	9	35	449	244	646	7e-90	298
rs:WP_041167430	DNA topoisomerase [Pseudomonas putida].	38.60	456	242	9	31	452	181	632	9e-90	298
rs:WP_041908197	DNA topoisomerase III [Enterobacter sp. BIDMC 29].	41.20	415	230	7	36	449	242	643	9e-90	299
rs:WP_032191370	DNA topoisomerase III [Escherichia coli].	41.49	417	231	7	36	449	242	648	9e-90	299
rs:WP_016973531	DNA topoisomerase III [Pseudomonas tolaasii].	38.95	421	243	6	33	452	238	645	9e-90	298
rs:WP_044503985	DNA topoisomerase [Megasphaera sp. NP3].	41.80	433	224	10	29	454	239	650	9e-90	300
rs:WP_041642718	DNA topoisomerase III, partial [Magnetococcus marinus].	43.30	358	198	2	36	392	208	561	9e-90	298
rs:WP_027603251	DNA topoisomerase III [Pseudomonas sp. LAMO17WK12:I2].	37.94	427	251	6	33	458	238	651	1e-89	298
rs:WP_019821571	DNA topoisomerase III [Vibrio splendidus].	38.76	436	252	7	29	459	229	654	1e-89	299
rs:WP_039429996	DNA topoisomerase III [Vibrio navarrensis].	41.46	369	209	1	36	404	255	616	1e-89	298
rs:WP_012535949	DNA topoisomerase III [Acidithiobacillus ferrooxidans].	39.56	450	230	10	29	455	238	668	1e-89	298
rs:WP_041154903	DNA topoisomerase III [Vibrio mytili].	41.46	369	209	2	36	404	255	616	1e-89	298
rs:WP_021112534	DNA topoisomerase III family protein [[Haemophilus] parasuis].	40.67	418	230	9	35	449	244	646	1e-89	298
rs:WP_033648773	DNA topoisomerase III [Serratia marcescens].	39.46	441	247	4	22	450	217	649	2e-89	298
rs:WP_033170946	DNA topoisomerase [Selenomonas sp. ND2010].	40.32	439	243	8	29	459	238	665	2e-89	302
rs:WP_014701085	DNA topoisomerase [Pectobacterium sp. SCC3193].	39.00	418	243	5	35	450	241	648	2e-89	298
rs:WP_016978867	DNA topoisomerase III [Pseudomonas fluorescens].	38.72	421	244	6	33	452	238	645	2e-89	297
rs:WP_031575408	DNA topoisomerase III, partial [Acidithiobacillus thiooxidans].	41.09	387	214	5	29	412	238	613	3e-89	298
rs:WP_012536731	DNA topoisomerase III [Acidithiobacillus ferrooxidans].	38.19	453	231	10	29	455	238	667	3e-89	297
tr:A0A0C8Q0Q4_SALTI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	40.38	416	238	5	36	450	242	648	3e-89	297
rs:WP_036768648	DNA topoisomerase III [Photorhabdus asymbiotica].	39.20	426	247	6	36	459	242	657	4e-89	297
rs:WP_015869774	DNA topoisomerase III [Edwardsiella ictaluri].	40.72	415	232	6	36	449	242	643	4e-89	297
rs:WP_033690675	DNA topoisomerase, partial [Pseudomonas sp. TJI-51].	38.68	455	241	9	32	452	182	632	4e-89	296
rs:WP_040118093	DNA topoisomerase III [Enterobacter cloacae].	42.21	417	227	7	36	450	242	646	4e-89	297
tr:F0E713_PSEDT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	38.68	455	241	9	32	452	182	632	4e-89	296
rs:WP_024061224	DNA topoisomerase [Veillonella dispar].	38.87	476	244	12	19	452	230	700	4e-89	299
gpu:KP795701_31	DNA topoisomerase III [Vibrio sp. FF_307]	38.48	434	256	6	29	459	229	654	5e-89	298
tr:I3V5K3_PSEPU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	38.60	456	242	9	31	452	259	710	5e-89	298
rs:WP_008713605	DNA topoisomerase III [Veillonella sp. 3_1_44].	38.87	476	244	12	19	452	230	700	5e-89	299
rs:WP_033955320	DNA topoisomerase [Pseudomonas aeruginosa].	38.60	456	242	9	31	452	259	710	5e-89	298
rs:WP_048256391	DNA topoisomerase III [Pectobacterium carotovorum].	39.00	418	243	5	35	450	241	648	5e-89	296
rs:WP_025822161	DNA topoisomerase III [Shewanella marina].	40.16	386	230	1	35	420	250	634	5e-89	296
rs:WP_045994683	DNA topoisomerase III [Halomonas sp. S2151].	43.01	379	213	3	36	414	242	617	5e-89	295
rs:WP_039627610	DNA topoisomerase III [Vibrio ichthyoenteri].	40.92	369	211	1	36	404	255	616	5e-89	296
rs:WP_024269754	DNA topoisomerase III [Escherichia coli].	62.20	209	79	0	29	237	244	452	6e-89	291
rs:WP_005473440	DNA topoisomerase III [Vibrio sp. 16].	40.92	369	211	1	36	404	255	616	6e-89	296
rs:WP_014232576	DNA topoisomerase III [Vibrio sp. EJY3].	40.65	369	212	1	36	404	255	616	6e-89	296
rs:WP_041647363	DNA topoisomerase III, partial [Acidithiobacillus ferrooxidans].	42.46	391	208	7	29	416	238	614	7e-89	295
rs:WP_038133918	DNA topoisomerase III [Vibrio caribbeanicus].	40.92	369	211	1	36	404	255	616	7e-89	296
rs:WP_035686649	DNA topoisomerase III [Avibacterium paragallinarum].	38.76	418	235	7	36	450	245	644	8e-89	296
rs:WP_039482952	DNA topoisomerase III [Vibrio sinaloensis].	40.92	369	211	1	36	404	255	616	9e-89	295
rs:WP_006879407	DNA topoisomerase III [Vibrio brasiliensis].	40.92	369	211	1	36	404	255	616	1e-88	295
rs:WP_007901001	DNA topoisomerase III [Pseudomonas sp. GM102].	37.83	423	249	6	33	454	238	647	1e-88	295
rs:WP_023045227	DNA topoisomerase III [Photorhabdus temperata].	39.44	426	246	6	36	459	242	657	1e-88	296
rs:WP_031594540	DNA topoisomerase III [Pantoea agglomerans].	42.21	417	227	7	36	450	242	646	1e-88	296
tr:B7JBJ6_ACIF2	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	40.74	432	232	10	29	457	238	648	1e-88	296
rs:WP_042923338	MULTISPECIES: DNA topoisomerase [Pseudomonas stutzeri group].	38.02	455	245	8	31	452	259	709	1e-88	297
rs:WP_023053285	DNA topoisomerase III [Megasphaera sp. BV3C16-1].	39.30	430	240	9	29	454	237	649	1e-88	296
rs:WP_046061998	DNA topoisomerase III [Pseudomonas kilonensis].	38.41	427	249	6	33	458	238	651	1e-88	295
rs:WP_045666083	DNA topoisomerase [Pseudomonas sp. BRH_c35].	38.24	455	244	8	31	452	259	709	1e-88	296
rs:WP_038213471	DNA topoisomerase III [Vibrio variabilis].	40.92	369	211	1	36	404	255	616	1e-88	295
rs:WP_039011295	DNA topoisomerase III [Pseudomonas brassicacearum].	38.41	427	249	6	33	458	238	651	1e-88	295
rs:WP_033003857	DNA topoisomerase III, partial [Vibrio azureus].	37.31	469	241	9	36	459	236	696	2e-88	296
rs:WP_034947635	DNA topoisomerase III [Erwinia oleae].	38.46	416	242	6	36	449	242	645	2e-88	295
tr:V2N7C2_SALET	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	43.21	368	201	3	36	401	242	603	2e-88	294
rs:WP_004072118	DNA topoisomerase III [Desulfobacter postgatei].	37.92	480	235	8	32	459	239	707	2e-88	296
rs:WP_025622790	DNA topoisomerase III [Vibrio parahaemolyticus].	40.00	370	215	1	35	404	254	616	2e-88	295
rs:WP_003036629	DNA topoisomerase III [Citrobacter freundii].	42.21	417	227	7	36	450	242	646	2e-88	295
rs:WP_029793271	DNA topoisomerase III [Vibrio parahaemolyticus].	40.00	370	215	1	35	404	254	616	2e-88	295
rs:WP_045060819	DNA topoisomerase III [Pseudomonas sp. ES3-33].	38.06	423	248	6	33	454	238	647	2e-88	295
rs:WP_023118088	MULTISPECIES: hypothetical protein [Pseudomonas].	38.68	455	241	9	32	452	260	710	2e-88	296
rs:WP_013811158	MULTISPECIES: DNA topoisomerase III [Serratia].	40.14	416	240	3	36	450	242	649	3e-88	295
rs:WP_031840280	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	89	450	3e-88	290
rs:WP_010318864	DNA topoisomerase III [Vibrio ordalii].	41.02	373	213	1	32	404	251	616	3e-88	294
rs:WP_023004936	DNA topoisomerase III [Halomonas sp. PBN3].	42.48	379	215	2	36	414	242	617	3e-88	293
rs:WP_013060258	DNA topoisomerase III [Yersinia pestis].	40.14	416	240	3	36	450	242	649	3e-88	295
rs:WP_008077959	DNA topoisomerase III [Vibrio sinaloensis].	40.65	369	212	1	36	404	255	616	3e-88	294
rs:WP_025587447	DNA topoisomerase III [Vibrio parahaemolyticus].	40.11	369	214	1	36	404	255	616	3e-88	294
rs:WP_029290885	DNA topoisomerase III [Pseudomonas fluorescens].	38.30	423	247	6	33	454	238	647	3e-88	294
rs:WP_023205275	DNA topoisomerase III [Salmonella enterica].	41.35	416	232	6	36	450	242	646	3e-88	295
rs:WP_033872237	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	37.84	399	238	4	61	458	34	423	4e-88	287
rs:WP_006777725	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	41.35	416	232	6	36	450	242	646	4e-88	294
rs:WP_035565616	DNA topoisomerase III [Halomonas sp. KO116].	36.72	433	259	4	36	459	241	667	4e-88	296
rs:WP_039475777	DNA topoisomerase III [Vibrio sinaloensis].	40.92	369	211	1	36	404	255	616	4e-88	294
rs:WP_038191560	DNA topoisomerase III [Vibrio sinaloensis].	40.38	369	213	1	36	404	255	616	4e-88	294
tr:U3A8G4_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	36.89	469	243	8	36	459	236	696	4e-88	296
rs:WP_033962387	DNA topoisomerase [Pseudomonas aeruginosa].	38.02	455	245	8	31	452	259	709	4e-88	295
rs:WP_029807206	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	5e-88	293
tr:N2ILA1_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	37.95	440	250	8	36	458	244	677	5e-88	296
rs:WP_037031292	DNA topoisomerase III [Pseudomonas sp. HPB0071].	37.95	440	250	8	36	458	242	675	5e-88	296
rs:WP_020838689	DNA topoisomerase III [Vibrio parahaemolyticus].	40.11	369	214	1	36	404	255	616	6e-88	293
tr:Q6D9T7_PECAS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	41.91	377	209	5	74	450	282	648	6e-88	294
rs:WP_029827151	DNA topoisomerase III [Vibrio parahaemolyticus].	40.11	369	214	1	36	404	255	616	6e-88	293
rs:WP_024893846	DNA topoisomerase III [Acidithiobacillus thiooxidans].	42.03	395	219	6	16	406	232	620	7e-88	294
rs:WP_039290396	DNA topoisomerase III [Pectobacterium atrosepticum].	41.91	377	209	5	74	450	281	647	7e-88	293
rs:WP_025635400	DNA topoisomerase III [Vibrio parahaemolyticus].	40.11	369	214	1	36	404	255	616	7e-88	293
rs:WP_048322195	DNA topoisomerase III [Klebsiella pneumoniae].	41.35	416	232	6	36	450	242	646	7e-88	293
rs:WP_017110286	DNA topoisomerase III [Vibrio tasmaniensis].	38.76	436	252	7	29	459	229	654	7e-88	295
rs:WP_016190694	DNA topoisomerase III [Erwinia tracheiphila].	41.20	415	230	7	36	449	242	643	8e-88	293
rs:WP_045569553	DNA topoisomerase III [Vibrio sp. S234-5].	40.65	369	212	1	36	404	255	616	8e-88	293
rs:WP_004663540	DNA topoisomerase III [Pseudomonas savastanoi].	39.20	426	242	6	31	452	236	648	8e-88	293
rs:WP_025508845	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	8e-88	293
rs:WP_029434626	DNA topoisomerase III [Bilophila wadsworthia].	39.31	435	242	7	25	459	232	644	8e-88	294
rs:WP_037352392	DNA topoisomerase [Selenomonas sp. FC4001].	38.64	427	247	7	35	459	246	659	8e-88	295
rs:WP_029593103	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	41.35	416	232	6	36	450	242	646	9e-88	293
rs:WP_012822377	DNA topoisomerase III [Pectobacterium wasabiae].	38.52	418	244	6	35	450	241	647	9e-88	293
rs:WP_033874157	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	37.97	395	235	4	61	454	35	420	9e-88	287
rs:WP_012146809	DNA topoisomerase III [Serratia proteamaculans].	40.67	418	235	5	36	450	242	649	9e-88	293
rs:WP_026327811	DNA topoisomerase [Selenomonas bovis].	40.95	442	233	9	33	459	242	670	9e-88	297
rs:WP_047708679	DNA topoisomerase III [Vibrio parahaemolyticus].	40.11	369	214	1	36	404	255	616	1e-87	293
rs:WP_036520289	DNA topoisomerase III [Nitrincola sp. A-D6].	39.36	376	221	2	36	409	251	621	1e-87	292
rs:WP_004115565	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	41.35	416	232	6	36	450	242	646	1e-87	293
rs:WP_004072223	DNA topoisomerase III [Desulfobacter postgatei].	38.59	482	229	9	32	459	239	707	1e-87	294
rs:WP_008642133	DNA topoisomerase III [Cupriavidus sp. HMR-1].	39.42	449	244	11	26	452	266	708	1e-87	294
rs:WP_039092466	DNA topoisomerase III [Gallibacterium anatis].	38.04	418	238	7	36	450	245	644	1e-87	293
rs:WP_039085585	DNA topoisomerase III [Gallibacterium anatis].	38.04	418	238	7	36	450	245	644	1e-87	293
rs:WP_025526041	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	1e-87	292
rs:WP_003410932	DNA topoisomerase III [Pseudomonas syringae].	38.39	422	246	6	32	452	237	645	1e-87	292
rs:WP_031851482	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	1e-87	292
rs:WP_025609941	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	1e-87	292
rs:WP_016151302	hypothetical protein [Citrobacter sp. KTE151].	41.11	416	233	6	36	450	242	646	1e-87	293
rs:WP_039465481	DNA topoisomerase III [Vibrio navarrensis].	40.92	369	211	1	36	404	255	616	2e-87	293
rs:WP_021564887	hypothetical protein [Escherichia coli].	39.95	418	237	8	36	450	242	648	2e-87	293
rs:WP_019740450	DNA topoisomerase III, partial [Pseudomonas savastanoi].	39.20	426	242	6	31	452	144	556	2e-87	290
rs:WP_025516126	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	2e-87	292
rs:WP_039443542	DNA topoisomerase III [Vibrio navarrensis].	40.92	369	211	1	36	404	255	616	2e-87	292
rs:WP_017707254	DNA topoisomerase III, partial [Pseudomonas syringae].	39.91	426	239	6	31	452	25	437	2e-87	287
rs:WP_023585247	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	2e-87	292
rs:WP_025535495	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	2e-87	292
rs:WP_025500282	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	2e-87	292
rs:WP_025558293	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	2e-87	292
rs:WP_047659587	DNA topoisomerase III [Escherichia coli].	39.90	416	240	5	36	450	242	648	2e-87	292
rs:WP_029845242	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	2e-87	292
rs:WP_031815415	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	2e-87	292
rs:WP_042998113	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	41.11	416	233	6	36	450	242	646	2e-87	292
rs:WP_006749824	DNA topoisomerase III [Burkholderia ambifaria].	38.90	437	243	8	30	458	249	669	2e-87	293
rs:WP_038152891	DNA topoisomerase [Veillonella montpellierensis].	38.15	464	245	8	29	452	239	700	2e-87	295
rs:WP_045545704	DNA topoisomerase III [Vibrio sp. S512-13].	39.84	369	215	1	36	404	255	616	2e-87	292
rs:WP_006942369	DNA topoisomerase [Megasphaera micronuciformis].	41.03	429	231	10	29	452	237	648	2e-87	293
rs:WP_034948907	DNA topoisomerase III, partial [Erwinia oleae].	39.23	418	238	7	36	450	29	433	2e-87	286
rs:WP_025570202	DNA topoisomerase III [Vibrio parahaemolyticus].	40.11	369	214	1	36	404	255	616	2e-87	292
rs:WP_025541060	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	2e-87	292
rs:WP_020300890	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	38.24	421	246	6	33	452	238	645	2e-87	292
rs:WP_025636901	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	2e-87	292
rs:WP_006085455	DNA topoisomerase III [Shewanella baltica].	41.03	368	203	1	32	385	247	614	2e-87	293
rs:WP_033636010	DNA topoisomerase III [Serratia marcescens].	39.03	433	253	4	19	450	227	649	2e-87	292
rs:WP_040763483	DNA topoisomerase, partial [Sutterella parvirubra].	42.33	404	204	4	29	406	247	647	2e-87	291
tr:A0A0C4YA37_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	39.91	436	251	7	33	459	238	671	2e-87	295
rs:WP_039432611	DNA topoisomerase III [Vibrio navarrensis].	40.65	369	212	1	36	404	255	616	2e-87	292
rs:WP_047296704	DNA topoisomerase III [Pseudomonas fluorescens].	37.35	423	251	6	33	454	238	647	2e-87	292
rs:WP_045984985	DNA topoisomerase III [Vibrio coralliilyticus].	40.38	369	213	1	36	404	255	616	3e-87	291
rs:WP_024608541	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	37.01	435	260	5	35	458	241	672	3e-87	293
rs:WP_029833579	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	3e-87	291
rs:WP_025633667	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	3e-87	291
rs:WP_033555858	DNA topoisomerase III [Escherichia coli].	39.90	416	240	5	36	450	242	648	3e-87	292
rs:WP_026003740	DNA topoisomerase III [Pseudomonas luteola].	36.73	441	257	7	36	458	242	678	3e-87	293
rs:WP_024108348	DNA topoisomerase III [Dickeya dianthicola].	39.09	417	242	5	36	450	242	648	3e-87	292
rs:WP_042342345	DNA topoisomerase III [Escherichia coli].	39.90	416	240	5	36	450	242	648	3e-87	292
rs:WP_021544269	hypothetical protein [Escherichia coli].	39.95	418	237	8	36	450	242	648	3e-87	292
rs:WP_028255426	DNA topoisomerase [Veillonella magna].	37.47	491	250	11	16	452	224	711	3e-87	295
rs:WP_036509820	DNA topoisomerase III [Nitrincola sp. AK23].	37.28	405	237	3	36	436	251	642	3e-87	291
rs:WP_043004228	DNA topoisomerase III, partial [Vibrio anguillarum].	40.65	369	212	1	36	404	154	515	3e-87	288
rs:WP_025526834	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	3e-87	291
rs:WP_029802080	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	4e-87	291
rs:WP_025528100	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	4e-87	291
rs:WP_025638623	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	4e-87	291
rs:WP_024699733	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	4e-87	291
rs:WP_038206707	DNA topoisomerase III [Vibrio tubiashii].	40.65	369	212	1	36	404	255	616	4e-87	291
rs:WP_021822369	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	4e-87	291
rs:WP_021453258	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	4e-87	291
rs:WP_040089341	DNA topoisomerase III [Escherichia coli].	39.90	416	240	5	36	450	242	648	4e-87	291
tr:A0A059ZW14_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	40.66	423	232	9	31	445	235	646	4e-87	294
rs:WP_025631592	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	4e-87	291
rs:WP_017447821	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	4e-87	291
rs:WP_029815742	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	4e-87	291
rs:WP_025627208	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	4e-87	291
rs:WP_024910502	DNA topoisomerase III [Serratia multitudinisentens].	39.75	395	225	6	57	449	262	645	4e-87	291
rs:WP_029839225	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	4e-87	291
rs:WP_031849232	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	4e-87	291
rs:WP_025529541	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	4e-87	291
rs:WP_038938912	DNA topoisomerase III [Vibrio vulnificus].	41.46	369	209	2	36	404	255	616	4e-87	291
rs:WP_025499560	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	4e-87	291
rs:WP_025442128	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	4e-87	291
rs:WP_031856192	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	4e-87	291
tr:A9N2T9_SALPB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	40.05	417	235	7	36	450	242	645	4e-87	291
rs:WP_025552790	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	5e-87	291
rs:WP_045969710	DNA topoisomerase III [Xenorhabdus doucetiae].	39.14	419	242	6	36	452	242	649	5e-87	291
rs:WP_038156149	DNA topoisomerase III [Vibrio sp. B183].	40.38	369	213	1	36	404	255	616	5e-87	291
rs:WP_022550047	DNA topoisomerase III [Vibrio nigripulchritudo].	42.28	369	207	2	36	404	255	617	5e-87	291
rs:WP_041057988	DNA topoisomerase III [Vibrio owensii].	40.38	369	213	1	36	404	255	616	5e-87	291
rs:WP_029854479	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	5e-87	291
rs:WP_025793072	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	5e-87	291
rs:WP_020195690	DNA topoisomerase III [Vibrio owensii].	40.38	369	213	1	36	404	255	616	5e-87	291
rs:WP_023285893	hypothetical protein [Klebsiella pneumoniae].	38.70	416	243	6	36	450	242	646	5e-87	292
rs:WP_045965975	DNA topoisomerase III [Vibrio nigripulchritudo].	42.28	369	207	2	36	404	255	617	5e-87	291
rs:WP_025809783	DNA topoisomerase III [Pseudomonas chlororaphis].	37.95	419	247	7	36	452	241	648	5e-87	291
tr:A0A068QQ25_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	39.14	419	242	6	36	452	248	655	5e-87	291
rs:WP_004414842	DNA topoisomerase III [Vibrio orientalis].	40.65	369	212	1	36	404	255	616	5e-87	291
rs:WP_044292940	DNA topoisomerase III [Pseudomonas amygdali].	39.44	426	241	6	31	452	236	648	5e-87	291
rs:WP_038510307	DNA topoisomerase III [Vibrio coralliilyticus].	40.38	369	213	1	36	404	255	616	6e-87	291
rs:WP_042932890	DNA topoisomerase III, partial [Pseudomonas coronafaciens].	40.93	386	212	5	70	452	18	390	6e-87	284
rs:WP_034113353	DNA topoisomerase III [Pseudomonas fluorescens].	39.50	400	227	6	56	454	262	647	6e-87	291
rs:WP_013199786	DNA topoisomerase III [Erwinia billingiae].	39.81	417	237	7	36	450	242	646	6e-87	291
rs:WP_043046559	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	261	622	6e-87	290
tr:F2ZR01_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	40.93	386	212	5	70	452	27	399	6e-87	284
rs:WP_025591399	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	6e-87	291
rs:WP_003090102	DNA topoisomerase III [Pseudomonas aeruginosa].	38.64	396	232	4	61	454	267	653	7e-87	291
rs:WP_044023984	DNA topoisomerase III [Vibrio vulnificus].	41.46	369	209	2	36	404	255	616	7e-87	291
rs:WP_027607351	DNA topoisomerase III [Pseudomonas sp. LAMO17WK12:I2].	37.44	422	250	5	34	454	239	647	7e-87	291
rs:WP_044322389	DNA topoisomerase III [Pseudomonas amygdali].	39.44	426	241	6	31	452	236	648	7e-87	291
rs:WP_038896082	DNA topoisomerase III [Vibrio owensii].	40.38	369	213	1	36	404	255	616	7e-87	291
rs:WP_012089582	DNA topoisomerase III [Shewanella baltica].	41.03	368	203	1	32	385	247	614	7e-87	292
rs:WP_024702582	DNA topoisomerase III [Vibrio parahaemolyticus].	39.30	369	217	1	36	404	255	616	7e-87	290
rs:WP_029805727	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	7e-87	290
rs:WP_011334398	DNA topoisomerase III [Pseudomonas fluorescens].	37.68	422	249	6	32	452	237	645	7e-87	290
rs:WP_022607934	DNA topoisomerase III [Vibrio nigripulchritudo].	42.28	369	207	2	36	404	255	617	7e-87	291
rs:WP_009707306	DNA topoisomerase III [Vibrio sp. HENC-03].	40.38	369	213	1	36	404	255	616	8e-87	290
rs:WP_025611875	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	8e-87	290
rs:WP_017045245	DNA topoisomerase III [Vibrio ordalii].	40.65	369	212	1	36	404	255	616	8e-87	290
rs:WP_045595832	DNA topoisomerase III [Vibrio vulnificus].	41.46	369	209	2	36	404	255	616	8e-87	290
rs:WP_044707194	DNA topoisomerase III [Escherichia coli].	39.95	418	237	8	36	450	242	648	8e-87	291
rs:WP_006962977	DNA topoisomerase III [Vibrio coralliilyticus].	40.38	369	213	1	36	404	255	616	9e-87	290
rs:WP_007885442	DNA topoisomerase III [Pantoea sp. GM01].	39.23	418	238	7	36	450	242	646	9e-87	291
rs:WP_025521195	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	9e-87	290
rs:WP_010565137	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	37.35	423	251	6	33	454	238	647	9e-87	290
rs:WP_006082217	DNA topoisomerase III [Shewanella baltica].	41.03	368	203	1	32	385	247	614	9e-87	291
rs:WP_025605522	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	9e-87	290
rs:WP_025535135	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	9e-87	290
rs:WP_047687824	DNA topoisomerase III [Vibrio sp. ZOR0018].	40.92	369	211	1	36	404	255	616	9e-87	290
rs:WP_025628854	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	9e-87	290
gp:CP002469_2073	DNA topoisomerase III [Vibrio vulnificus MO6-24/O]	41.46	369	209	2	36	404	264	625	9e-87	290
rs:WP_025553795	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	9e-87	290
rs:WP_041956145	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	1e-86	290
rs:WP_045629174	DNA topoisomerase III [Vibrio vulnificus].	41.46	369	209	2	36	404	255	616	1e-86	290
rs:WP_029861830	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	1e-86	290
rs:WP_025532715	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	1e-86	290
rs:WP_025627575	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	1e-86	290
rs:WP_029810451	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	1e-86	290
rs:WP_045604644	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	1e-86	290
rs:WP_021449869	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	1e-86	290
rs:WP_011080930	DNA topoisomerase III [Vibrio vulnificus].	41.46	369	209	2	36	404	255	616	1e-86	290
rs:WP_047234969	DNA topoisomerase III [Aeromonas hydrophila].	36.64	434	263	5	36	459	242	673	1e-86	292
rs:WP_026050788	DNA topoisomerase III [Vibrio vulnificus].	41.46	369	209	2	36	404	255	616	1e-86	290
rs:WP_017042547	DNA topoisomerase III [Vibrio ordalii].	40.65	369	212	1	36	404	255	616	1e-86	290
rs:WP_031382112	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	1e-86	290
rs:WP_045588151	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	1e-86	290
rs:WP_045387311	DNA topoisomerase III [Vibrio rotiferianus].	40.65	369	212	1	36	404	255	616	1e-86	290
rs:WP_039450498	DNA topoisomerase III [Vibrio vulnificus].	41.46	369	209	2	36	404	255	616	1e-86	290
rs:WP_025508783	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	1e-86	290
rs:WP_047109038	DNA topoisomerase III [Vibrio vulnificus].	41.46	369	209	2	36	404	255	616	1e-86	290
rs:WP_012587335	DNA topoisomerase III [Shewanella baltica].	41.03	368	203	1	32	385	247	614	1e-86	291
rs:WP_029864161	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	1e-86	290
rs:WP_029842486	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	1e-86	290
rs:WP_021704335	DNA topoisomerase III [Vibrio proteolyticus].	40.38	369	213	1	36	404	255	616	1e-86	290
rs:WP_045325423	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	1e-86	290
rs:WP_029857514	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	1e-86	290
rs:WP_020841080	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	1e-86	290
rs:WP_043008804	DNA topoisomerase III [Vibrio coralliilyticus].	40.38	369	213	1	36	404	255	616	1e-86	290
tr:H3KDU7_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	42.33	404	204	4	29	406	247	647	1e-86	292
rs:WP_006743281	DNA topoisomerase III [Vibrio antiquarius].	39.84	369	215	1	36	404	255	616	1e-86	290
tr:A0A0E5E1I9_SALTI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CQU98730.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CQU98730.1};	39.66	416	241	5	36	450	242	648	1e-86	290
rs:WP_031778422	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	1e-86	290
rs:WP_042103769	DNA topoisomerase III [Escherichia coli].	39.33	417	241	6	36	450	242	648	1e-86	290
rs:WP_031816622	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	1e-86	290
rs:WP_047123684	DNA topoisomerase III [Vibrio parahaemolyticus].	39.30	369	217	1	36	404	255	616	1e-86	290
rs:WP_005485385	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	1e-86	290
rs:WP_029842060	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	1e-86	290
rs:WP_029808658	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	1e-86	290
rs:WP_029796813	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	2e-86	290
rs:WP_012004777	DNA topoisomerase III [Serratia proteamaculans].	39.66	416	242	3	36	450	242	649	2e-86	290
rs:WP_046481894	DNA topoisomerase III [Pseudomonas veronii].	37.35	423	251	5	33	454	238	647	2e-86	290
rs:WP_033808633	DNA topoisomerase III [Escherichia coli].	39.95	418	237	8	36	450	242	648	2e-86	290
rs:WP_045612368	DNA topoisomerase III [Vibrio vulnificus].	41.46	369	209	2	36	404	255	616	2e-86	290
rs:WP_025503057	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	2e-86	290
rs:WP_038884305	DNA topoisomerase III [Vibrio rotiferianus].	40.38	369	213	1	36	404	255	616	2e-86	290
rs:WP_035889396	DNA topoisomerase III [Kosakonia radicincitans].	39.05	402	231	5	51	450	256	645	2e-86	290
rs:WP_001696682	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	39.23	418	242	6	36	450	242	650	2e-86	290
rs:WP_005461760	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	2e-86	290
rs:WP_027697374	DNA topoisomerase III [Vibrio litoralis].	40.92	369	214	2	36	404	255	619	2e-86	290
rs:WP_045953833	DNA topoisomerase III [Vibrio sp. S2757].	40.38	369	213	1	36	404	255	616	2e-86	290
tr:B6AP75_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	39.82	437	243	11	17	451	228	646	2e-86	290
rs:WP_025505736	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	2e-86	290
rs:WP_021462518	DNA topoisomerase III [Gallibacterium anatis].	37.56	418	240	7	36	450	245	644	2e-86	290
rs:WP_022600355	DNA topoisomerase III [Vibrio nigripulchritudo].	42.01	369	208	2	36	404	255	617	2e-86	290
rs:WP_013856386	DNA topoisomerase III [Vibrio anguillarum].	40.92	369	211	1	36	404	255	616	2e-86	289
rs:WP_042780750	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	2e-86	289
tr:A0A0C6ES95_PSEAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	38.38	396	233	4	61	454	267	653	2e-86	290
rs:WP_004581684	DNA topoisomerase III [Marinobacter nanhaiticus].	36.00	475	242	5	35	459	247	709	2e-86	291
rs:WP_025789721	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	2e-86	289
rs:WP_001177799	DNA topoisomerase III [Escherichia coli].	39.66	416	241	5	36	450	242	648	2e-86	290
rs:WP_039842429	DNA topoisomerase III [Vibrio owensii].	40.38	369	213	1	36	404	255	616	2e-86	289
rs:WP_003435765	DNA topoisomerase III [Pseudomonas syringae].	40.24	425	239	6	31	452	236	648	2e-86	290
rs:WP_001682052	DNA topoisomerase III [Escherichia coli].	39.57	417	239	7	36	450	242	647	2e-86	290
rs:WP_024792519	DNA topoisomerase III [Salmonella enterica].	39.81	417	236	7	36	450	242	645	2e-86	290
rs:WP_025521521	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	2e-86	289
rs:WP_045623503	DNA topoisomerase III [Vibrio vulnificus].	41.19	369	210	2	36	404	255	616	2e-86	289
rs:WP_017048533	DNA topoisomerase III [Vibrio ordalii].	40.38	369	213	1	36	404	255	616	2e-86	289
rs:WP_046482630	DNA topoisomerase III [Pseudomonas veronii].	37.24	427	252	6	36	459	241	654	2e-86	290
rs:WP_046497084	DNA topoisomerase III [Citrobacter amalonaticus].	39.81	417	236	7	36	450	242	645	2e-86	290
rs:WP_032308776	DNA topoisomerase III [Escherichia coli].	39.71	418	238	8	36	450	242	648	2e-86	290
tr:A0A0E8Q0U3_SALTI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CRF58224.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRF58224.1};	39.66	416	241	5	36	450	242	648	2e-86	290
rs:WP_045594548	DNA topoisomerase III [Vibrio vulnificus].	41.19	369	210	2	36	404	255	616	2e-86	289
rs:WP_011149881	DNA topoisomerase III [Vibrio vulnificus].	41.19	369	210	2	36	404	255	616	2e-86	289
rs:WP_025623522	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	2e-86	289
rs:WP_025556707	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	2e-86	289
rs:WP_017635824	DNA topoisomerase III [Vibrio sp. 712i1].	39.73	370	216	1	35	404	254	616	2e-86	289
rs:WP_034054055	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	37.37	396	237	4	61	454	17	403	2e-86	283
rs:WP_047609018	DNA topoisomerase III [Rahnella aquatilis].	39.14	419	237	7	36	450	242	646	2e-86	290
rs:WP_045619965	DNA topoisomerase III [Vibrio vulnificus].	41.19	369	210	2	36	404	255	616	2e-86	289
rs:WP_001177802	DNA topoisomerase III [Escherichia coli].	39.66	416	241	5	36	450	242	648	2e-86	290
rs:WP_046337393	DNA topoisomerase III [Xenorhabdus bovienii].	39.18	416	237	7	36	449	242	643	3e-86	290
rs:WP_009843452	DNA topoisomerase III [Vibrio sp. AND4].	40.11	369	214	1	36	404	255	616	3e-86	289
rs:WP_045607374	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	3e-86	289
rs:WP_029851232	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	3e-86	289
rs:WP_003050384	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	38.38	396	233	4	61	454	267	653	3e-86	290
rs:WP_005494459	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	3e-86	289
rs:WP_038161991	DNA topoisomerase III [Trabulsiella guamensis].	39.81	417	236	7	36	450	242	645	3e-86	289
tr:K5V6Y2_9VIBR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	40.11	369	214	1	36	404	255	616	3e-86	289
rs:WP_045405705	DNA topoisomerase III [Vibrio jasicida].	40.11	369	214	1	36	404	255	616	3e-86	289
tr:H1BTD4_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	39.90	416	240	5	36	450	242	648	3e-86	289
rs:WP_031415725	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	3e-86	289
rs:WP_025546308	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	3e-86	289
rs:WP_001177801	DNA topoisomerase III [Escherichia coli].	39.42	416	242	4	36	450	242	648	3e-86	289
rs:WP_017049114	DNA topoisomerase III [Vibrio ordalii].	40.38	369	213	1	36	404	255	616	3e-86	289
tr:G5S0U4_SALET	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	43.53	363	189	5	94	455	3	350	3e-86	280
rs:WP_018715759	DNA topoisomerase III [Brachymonas chironomi].	38.38	396	233	4	61	454	267	653	3e-86	289
rs:WP_021454915	DNA topoisomerase III [Vibrio coralliilyticus].	40.11	369	214	1	36	404	255	616	3e-86	289
rs:WP_021580322	hypothetical protein [Escherichia coli].	39.66	416	241	5	36	450	242	648	3e-86	289
rs:WP_044423294	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	38.41	427	244	7	31	452	236	648	3e-86	289
tr:A0A061Q7A3_9VIBR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	40.11	369	214	1	36	404	240	601	3e-86	288
rs:WP_004402186	DNA topoisomerase III [Vibrio nigripulchritudo].	42.28	369	207	2	36	404	255	617	3e-86	289
rs:WP_026130810	DNA topoisomerase III [Vibrio vulnificus].	41.19	369	210	2	36	404	255	616	3e-86	289
rs:WP_005532611	DNA topoisomerase III [Vibrio campbellii].	40.11	369	214	1	36	404	255	616	3e-86	289
rs:WP_019276521	DNA topoisomerase III [Vibrio coralliilyticus].	40.11	369	214	1	36	404	255	616	3e-86	289
rs:WP_011847173	DNA topoisomerase III [Shewanella baltica].	41.03	368	203	1	32	385	247	614	4e-86	290
rs:WP_038263715	DNA topoisomerase III [Xenorhabdus cabanillasii].	37.83	415	245	5	36	449	242	644	4e-86	289
rs:WP_046029173	DNA topoisomerase III [Vibrio vulnificus].	41.19	369	210	2	36	404	255	616	4e-86	289
rs:WP_014542454	DNA topoisomerase III [Erwinia sp. Ejp617].	38.85	417	241	6	36	450	242	646	4e-86	289
rs:WP_043357816	hypothetical protein, partial [Cupriavidus basilensis].	39.68	431	249	7	33	454	238	666	4e-86	289
rs:WP_045588988	DNA topoisomerase III [Vibrio vulnificus].	41.19	369	210	2	36	404	255	616	4e-86	288
rs:WP_039467859	DNA topoisomerase III [Vibrio vulnificus].	41.19	369	210	2	36	404	255	616	4e-86	288
tr:F3FN33_PSESX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	39.67	426	240	6	31	452	132	544	4e-86	286
rs:WP_045608605	DNA topoisomerase III [Vibrio vulnificus].	41.19	369	210	2	36	404	255	616	4e-86	288
rs:WP_039948979	DNA topoisomerase III [Vibrio ichthyoenteri].	41.03	351	200	1	36	386	255	598	4e-86	288
rs:WP_047733265	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	4e-86	288
rs:WP_008075309	DNA topoisomerase III [Pseudomonas sp. GM79].	36.88	423	253	6	33	454	238	647	4e-86	288
rs:WP_039264698	DNA topoisomerase III [Enterobacter cloacae].	41.49	417	230	7	36	450	242	646	4e-86	289
rs:WP_010449456	DNA topoisomerase III [Vibrio rotiferianus].	40.38	369	213	1	36	404	255	616	4e-86	288
rs:WP_047481150	DNA topoisomerase III [Vibrio campbellii].	40.11	369	214	1	36	404	255	616	4e-86	288
rs:WP_001401071	DNA topoisomerase III family protein [Escherichia coli].	39.90	416	240	5	36	450	242	648	5e-86	289
rs:WP_015297075	DNA topoisomerase III [Vibrio parahaemolyticus].	39.30	369	217	1	36	404	255	616	5e-86	288
rs:WP_032676550	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	39.81	417	236	7	36	450	242	645	5e-86	289
rs:WP_025578174	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	5e-86	288
rs:WP_039540432	DNA topoisomerase III [Vibrio vulnificus].	41.19	369	210	2	36	404	255	616	5e-86	288
rs:WP_005439724	DNA topoisomerase III [Vibrio harveyi].	39.84	369	215	1	36	404	255	616	5e-86	288
rs:WP_023434789	DNA topoisomerase III [Pseudomonas aeruginosa].	37.88	396	235	4	61	454	267	653	5e-86	289
rs:WP_029846690	DNA topoisomerase III [Vibrio parahaemolyticus].	39.30	369	217	1	36	404	255	616	5e-86	288
rs:WP_045974983	DNA topoisomerase III [Vibrio neptunius].	40.11	369	214	1	36	404	255	616	5e-86	288
rs:WP_029831738	DNA topoisomerase III [Vibrio parahaemolyticus].	39.84	369	215	1	36	404	255	616	5e-86	288
rs:WP_001428196	DNA topoisomerase III family protein [Escherichia coli].	39.90	416	240	5	36	450	242	648	5e-86	288
rs:WP_038891461	DNA topoisomerase III [Vibrio campbellii].	40.11	369	214	1	36	404	255	616	6e-86	288
rs:WP_014343684	DNA topoisomerase III [Aliivibrio fischeri].	37.33	434	255	7	36	459	238	664	6e-86	290
rs:WP_013391789	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	38.23	395	234	4	61	454	267	652	6e-86	289
rs:WP_048330707	DNA topoisomerase III [Klebsiella pneumoniae].	41.49	417	230	7	36	450	242	646	6e-86	288
rs:WP_032636758	DNA topoisomerase III [Enterobacter sp. MGH 15].	40.62	416	235	6	36	450	242	646	6e-86	288
rs:WP_005593919	DNA topoisomerase III [Vibrio scophthalmi].	41.03	351	200	1	36	386	255	598	6e-86	288
rs:WP_012128555	DNA topoisomerase III [Vibrio campbellii].	40.11	369	214	1	36	404	255	616	6e-86	288
rs:WP_039555145	DNA topoisomerase III [Vibrio vulnificus].	40.92	369	211	2	36	404	255	616	6e-86	288
rs:WP_038991132	DNA topoisomerase III [Klebsiella pneumoniae].	40.38	416	236	5	36	450	242	646	6e-86	288
rs:WP_040988788	DNA topoisomerase III [Vibrio sp. DCR 1-4-2].	39.84	369	215	1	36	404	255	616	6e-86	288
rs:WP_039512817	DNA topoisomerase III [Pectobacterium carotovorum].	38.13	417	247	4	36	450	243	650	6e-86	288
rs:WP_005396516	DNA topoisomerase III [Vibrio alginolyticus].	39.57	369	216	1	36	404	255	616	6e-86	288
rs:WP_028761026	DNA topoisomerase III [Shewanella putrefaciens].	40.76	368	204	1	32	385	247	614	6e-86	289
rs:WP_029655590	DNA topoisomerase III [Marinobacter daepoensis].	35.80	500	271	8	3	459	220	712	6e-86	290
rs:WP_045625682	DNA topoisomerase III [Vibrio parahaemolyticus].	39.30	369	217	1	36	404	255	616	6e-86	288
rs:WP_045407416	DNA topoisomerase III [Vibrio jasicida].	38.19	432	252	7	36	459	238	662	6e-86	290
rs:WP_045816928	DNA topoisomerase III [Pantoea sp. SM3].	39.14	419	237	8	36	450	242	646	7e-86	289
rs:WP_045480696	DNA topoisomerase III [Vibrio owensii].	40.11	369	214	1	36	404	255	616	7e-86	288
rs:WP_031828274	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	7e-86	288
rs:WP_047685499	DNA topoisomerase III [Xenorhabdus sp. NBAII XenSa04].	36.64	434	262	5	36	459	242	672	7e-86	290
tr:F9S2S7_9VIBR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	41.03	351	200	1	36	386	266	609	7e-86	288
rs:WP_047739043	DNA topoisomerase III [Pseudomonas chlororaphis].	37.14	420	251	6	36	454	241	648	7e-86	288
rs:WP_005444645	DNA topoisomerase III [Vibrio harveyi].	40.11	369	214	1	36	404	255	616	7e-86	288
rs:WP_006714205	DNA topoisomerase III [Vibrio ichthyoenteri].	37.73	432	254	7	36	459	240	664	7e-86	289
rs:WP_033907348	DNA topoisomerase III [Vibrio sp. OY15].	39.57	369	216	1	36	404	255	616	8e-86	288
rs:WP_017189344	DNA topoisomerase III [Vibrio harveyi].	40.11	369	214	1	36	404	255	616	8e-86	288
rs:WP_022591550	DNA topoisomerase III [Vibrio nigripulchritudo].	42.01	369	208	2	36	404	255	617	8e-86	288
rs:WP_047725803	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	8e-86	288
rs:WP_022613230	DNA topoisomerase III [Vibrio nigripulchritudo].	42.01	369	208	2	36	404	255	617	8e-86	288
rs:WP_046874516	DNA topoisomerase III [Vibrio alginolyticus].	39.57	369	216	1	36	404	255	616	8e-86	288
rs:WP_024667013	DNA topoisomerase III [Pseudomonas syringae].	40.14	426	238	6	31	452	236	648	9e-86	288
tr:F9ZPH5_ACICS	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	39.20	426	236	7	29	443	235	648	9e-86	288
rs:WP_039313330	DNA topoisomerase III [Pectobacterium carotovorum].	37.91	430	256	4	23	450	230	650	9e-86	288
rs:WP_017821143	DNA topoisomerase III [Vibrio alginolyticus].	39.57	369	216	1	36	404	255	616	1e-85	288
rs:WP_023650177	DNA topoisomerase III family protein, partial [Vibrio parahaemolyticus].	40.46	351	202	1	54	404	12	355	1e-85	280
rs:WP_025541336	DNA topoisomerase III [Vibrio parahaemolyticus].	39.30	369	217	1	36	404	255	616	1e-85	287
rs:WP_017817824	DNA topoisomerase III [Vibrio harveyi].	40.11	369	214	1	36	404	255	616	1e-85	287
rs:WP_005384913	DNA topoisomerase III [Vibrio alginolyticus].	39.57	369	216	1	36	404	255	616	1e-85	287
rs:WP_009698532	DNA topoisomerase III [Vibrio sp. HENC-01].	40.11	369	214	1	36	404	255	616	1e-85	287
rs:WP_042992894	DNA topoisomerase III [Bordetella bronchiseptica].	38.23	395	234	4	61	454	267	652	1e-85	288
rs:WP_027899045	DNA topoisomerase III [Pseudomonas syringae].	38.04	418	246	8	35	450	240	646	1e-85	288
rs:WP_005380714	DNA topoisomerase III [Vibrio alginolyticus].	39.57	369	216	1	36	404	255	616	1e-85	287
rs:WP_044129469	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	1e-85	287
rs:WP_042522502	DNA topoisomerase III [Vibrio alginolyticus].	39.57	369	216	1	36	404	255	616	1e-85	287
rs:WP_031848119	DNA topoisomerase III [Vibrio parahaemolyticus].	39.57	369	216	1	36	404	255	616	1e-85	287
rs:WP_041635735	DNA topoisomerase III [Acidithiobacillus caldus].	39.20	426	236	7	29	443	237	650	1e-85	288
rs:WP_038855881	DNA topoisomerase III [Pseudomonas fluorescens].	38.99	395	228	5	60	454	266	647	1e-85	287
rs:WP_038968960	DNA topoisomerase III [Vibrio vulnificus].	40.92	369	211	2	36	404	255	616	1e-85	287
rs:WP_032608280	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	41.25	417	231	7	36	450	242	646	1e-85	288
rs:WP_042094135	DNA topoisomerase III [Escherichia coli].	39.42	416	242	5	36	450	242	648	1e-85	288
rs:WP_046816037	DNA topoisomerase III [Pseudomonas putida].	38.00	421	247	6	33	452	238	645	1e-85	287
rs:WP_038925525	DNA topoisomerase III [Dickeya zeae].	37.98	416	248	4	36	450	242	648	1e-85	288
rs:WP_038871241	DNA topoisomerase III [Vibrio jasicida].	39.57	369	216	1	36	404	255	616	1e-85	287
tr:A0A061PRR0_9VIBR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	39.57	369	216	1	36	404	255	616	1e-85	287
rs:WP_038881887	DNA topoisomerase III [Vibrio jasicida].	39.57	369	216	1	36	404	255	616	2e-85	287
rs:WP_001242113	DNA topoisomerase III [Escherichia coli].	39.00	418	243	6	36	450	242	650	2e-85	287
rs:WP_045146249	DNA topoisomerase III [Escherichia coli].	39.00	418	243	6	36	450	242	650	2e-85	287
rs:WP_020331263	DNA topoisomerase III [Vibrio fluvialis].	38.96	403	232	2	36	438	255	643	2e-85	287
rs:WP_035209415	DNA topoisomerase III [Acidithiobacillus thiooxidans].	41.22	427	221	12	31	445	236	644	2e-85	288
rs:WP_011919518	DNA topoisomerase III [Shewanella putrefaciens].	40.76	368	204	1	32	385	247	614	2e-85	288
rs:WP_047104534	DNA topoisomerase III [Vibrio alginolyticus].	39.57	369	216	1	36	404	255	616	2e-85	287
rs:WP_010188183	conjugal transfer protein TraE [Sphingomonas sp. PAMC 26605].	35.60	486	254	5	31	459	234	717	2e-85	288
rs:WP_045453629	DNA topoisomerase III [Vibrio campbellii].	39.84	369	215	1	36	404	255	616	2e-85	286
rs:WP_045421631	DNA topoisomerase III [Vibrio campbellii].	39.84	369	215	1	36	404	255	616	2e-85	286
rs:WP_005432974	DNA topoisomerase III [Vibrio campbellii].	39.84	369	215	1	36	404	255	616	2e-85	286
rs:WP_020432484	DNA topoisomerase III [Vibrio fluvialis].	38.96	403	232	2	36	438	255	643	2e-85	286
rs:WP_045369398	DNA topoisomerase III [Vibrio campbellii].	39.84	369	215	1	36	404	255	616	2e-85	286
rs:WP_029790477	DNA topoisomerase III [Vibrio harveyi].	39.84	369	215	1	36	404	255	616	2e-85	286
rs:WP_046035426	DNA topoisomerase III [Pseudomonas fluorescens].	38.48	395	230	5	56	450	262	643	2e-85	286
rs:WP_042606006	DNA topoisomerase III [Vibrio harveyi].	39.57	369	216	1	36	404	255	616	3e-85	286
rs:WP_011899410	DNA topoisomerase III [Aeromonas salmonicida].	36.64	434	263	5	36	459	242	673	3e-85	288
rs:WP_043082055	DNA topoisomerase III [Pluralibacter gergoviae].	41.25	417	231	7	36	450	242	646	3e-85	286
rs:WP_039986868	DNA topoisomerase III [Vibrio owensii].	40.11	369	214	1	36	404	255	616	3e-85	286
rs:WP_001720566	DNA topoisomerase III family protein [Escherichia coli].	39.66	416	241	5	36	450	242	648	3e-85	286
rs:WP_039507416	DNA topoisomerase III [Pectobacterium carotovorum].	39.81	417	238	7	36	450	242	647	3e-85	286
rs:WP_042133161	DNA topoisomerase III [Pseudomonas oryzihabitans].	39.95	418	238	6	36	450	241	648	3e-85	286
tr:S6U3B9_PSESF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	39.67	426	240	6	31	452	224	636	3e-85	286
rs:WP_016486405	DNA topoisomerase III [Pseudomonas putida].	37.27	432	256	7	29	459	233	650	3e-85	286
rs:WP_023087320	MULTISPECIES: hypothetical protein [Pseudomonas].	37.97	395	235	4	61	454	267	652	3e-85	287
rs:WP_044393820	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	39.91	426	239	6	31	452	236	648	3e-85	286
rs:WP_039974109	DNA topoisomerase III [Vibrio jasicida].	39.84	369	215	1	36	404	255	616	4e-85	286
rs:WP_045419892	DNA topoisomerase III [Vibrio jasicida].	39.84	369	215	1	36	404	255	616	4e-85	286
rs:WP_023653786	DNA topoisomerase III [Erwinia piriflorinigrans].	38.61	417	242	6	36	450	242	646	4e-85	286
rs:WP_046720009	DNA topoisomerase III [Pseudomonas syringae].	39.91	426	239	6	31	452	236	648	4e-85	286
rs:WP_020342662	DNA topoisomerase III [Pseudomonas syringae].	39.67	426	240	6	31	452	236	648	5e-85	286
rs:WP_003425069	DNA topoisomerase III [Pseudomonas syringae].	39.91	426	239	6	31	452	236	648	5e-85	286
rs:WP_014610819	DNA topoisomerase III [Shewanella putrefaciens].	40.76	368	204	1	32	385	247	614	5e-85	287
rs:WP_016567477	DNA topoisomerase III [Pseudomonas syringae].	39.91	426	239	6	31	452	236	648	5e-85	286
rs:WP_005498870	DNA topoisomerase III [Shewanella benthica].	37.86	412	241	3	32	438	247	648	5e-85	285
rs:WP_008937881	DNA topoisomerase III [Marinobacter santoriniensis].	36.25	469	247	6	35	458	253	714	5e-85	287
rs:WP_028257636	DNA topoisomerase [Veillonella montpellierensis].	37.72	464	247	8	29	452	239	700	5e-85	288
rs:WP_045377329	DNA topoisomerase III [Vibrio campbellii].	39.84	369	215	1	36	404	255	616	6e-85	285
rs:WP_035241401	DNA topoisomerase III [Desulfobacter vibrioformis].	39.26	433	235	8	32	456	239	651	6e-85	287
rs:WP_035241401	DNA topoisomerase III [Desulfobacter vibrioformis].	52.08	48	18	1	417	459	660	707	1e-05	58.5
tr:E6QCV3_9ZZZZ	SubName: Full=Putative DNA topoisomerase III (TopB) {ECO:0000313|EMBL:CBI05029.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI05029.1};	38.50	452	233	11	29	455	238	669	6e-85	286
rs:WP_011788910	DNA topoisomerase III [Shewanella sp. W3-18-1].	40.76	368	204	1	32	385	247	614	6e-85	287
rs:WP_001536202	DNA topoisomerase III family protein [Escherichia coli].	39.42	416	242	5	36	450	242	648	6e-85	286
rs:WP_037023194	DNA topoisomerase III [Pseudomonas sp. 20_BN].	38.76	387	234	2	23	408	228	612	6e-85	285
rs:WP_044209346	DNA topoisomerase III [Pectobacterium carotovorum].	40.21	378	216	3	74	450	282	650	7e-85	286
rs:WP_044311780	DNA topoisomerase III [Pseudomonas syringae].	39.91	426	239	6	31	452	236	648	7e-85	286
rs:WP_021014746	DNA topoisomerase III [Serratia sp. ATCC 39006].	39.23	418	238	7	36	450	242	646	7e-85	286
rs:WP_048258548	DNA topoisomerase III [Pectobacterium carotovorum].	40.63	379	213	4	74	450	282	650	7e-85	286
rs:WP_001422194	DNA topoisomerase III family protein [Escherichia coli].	39.42	416	242	5	36	450	242	648	8e-85	285
rs:WP_024763865	DNA topoisomerase III [Pseudomonas nitroreducens].	37.97	395	235	4	61	454	267	652	8e-85	286
rs:WP_042558370	DNA topoisomerase III [Pseudomonas fluorescens].	36.82	421	252	6	33	452	238	645	8e-85	285
rs:WP_019332795	DNA topoisomerase III [Pseudomonas syringae].	39.44	426	241	6	31	452	236	648	8e-85	285
rs:WP_033879165	DNA topoisomerase III [Escherichia coli].	39.42	416	242	5	36	450	242	648	8e-85	285
rs:WP_033965820	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	36.82	421	255	6	36	454	166	577	8e-85	283
rs:WP_014204652	DNA topoisomerase III [Vibrio furnissii].	40.38	369	213	1	36	404	255	616	8e-85	285
rs:WP_032080988	DNA topoisomerase III [Vibrio fluvialis].	40.38	369	213	1	36	404	255	616	9e-85	285
rs:WP_004724160	DNA topoisomerase III [Vibrio furnissii].	40.38	369	213	1	36	404	255	616	9e-85	285
tr:C6I107_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	41.05	419	225	11	34	445	235	638	9e-85	287
rs:WP_021707943	DNA topoisomerase III [Vibrio azureus].	39.57	369	216	1	36	404	255	616	9e-85	285
rs:WP_033962290	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	37.97	395	235	4	61	454	267	652	9e-85	285
rs:WP_038903512	DNA topoisomerase III [Dickeya zeae].	37.74	416	249	4	36	450	242	648	1e-84	285
rs:WP_042601263	DNA topoisomerase III [Vibrio harveyi].	39.57	369	216	1	36	404	255	616	1e-84	285
rs:WP_002541082	DNA topoisomerase III [Grimontia indica].	39.65	401	232	4	36	436	251	641	1e-84	285
rs:WP_003235825	DNA topoisomerase III [Pseudomonas fluorescens].	36.82	421	252	6	33	452	238	645	1e-84	285
rs:WP_022953535	DNA topoisomerase III [Leucothrix mucor].	39.95	378	201	2	35	386	250	627	1e-84	285
tr:E5B1P7_ERWAM	SubName: Full=K03169 DNA topoisomerase III {ECO:0000313|EMBL:CBX79398.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBX79398.1};	38.85	417	241	7	36	450	146	550	1e-84	283
rs:WP_023108431	hypothetical protein [Pseudomonas aeruginosa].	37.97	395	235	4	61	454	267	652	1e-84	285
rs:WP_005793094	DNA topoisomerase III [Acidovorax delafieldii].	38.38	396	229	5	61	454	267	649	1e-84	285
rs:WP_021519870	hypothetical protein [Escherichia coli].	39.05	420	238	5	36	450	242	648	1e-84	285
rs:WP_010644027	DNA topoisomerase III [Vibrio campbellii].	39.84	369	215	1	36	404	255	616	1e-84	285
rs:WP_008930006	DNA topoisomerase III [Alcanivorax hongdengensis].	37.38	420	250	5	36	454	241	648	1e-84	285
rs:WP_045282284	DNA topoisomerase III [Enterobacter sp. 44593].	40.38	416	236	6	36	450	242	646	1e-84	285
rs:WP_001175890	DNA topoisomerase III [Escherichia coli].	39.05	420	238	5	36	450	242	648	1e-84	285
rs:WP_026052510	DNA topoisomerase III [Gayadomonas joobiniege].	40.26	385	218	3	32	413	247	622	1e-84	284
rs:WP_027597847	DNA topoisomerase III [Pseudomonas sp. MOIL14HWK12:I2].	39.33	417	242	5	36	450	241	648	2e-84	285
rs:WP_045397957	MULTISPECIES: DNA topoisomerase III [Vibrio].	39.84	369	215	1	36	404	255	616	2e-84	284
rs:WP_005787064	DNA topoisomerase III [Pseudomonas synxantha].	37.83	423	249	5	33	454	238	647	2e-84	284
rs:WP_044783964	DNA topoisomerase III [Escherichia coli].	39.05	420	238	5	36	450	242	648	2e-84	285
rs:WP_044362581	DNA topoisomerase III [Vibrio fluvialis].	40.38	369	213	1	36	404	255	616	2e-84	284
rs:WP_027979348	DNA topoisomerase III [gamma proteobacterium L18].	38.37	417	240	7	36	450	241	642	2e-84	285
rs:WP_009387842	DNA topoisomerase III [Vibrio sp. N418].	40.74	351	201	1	36	386	255	598	2e-84	284
rs:WP_021243382	conjugal transfer protein TraE [Sphingobium baderi].	36.72	482	246	6	35	459	238	717	2e-84	286
rs:WP_006646506	DNA topoisomerase III [Photobacterium sp. SKA34].	40.85	355	209	1	32	386	247	600	2e-84	284
rs:WP_047703557	DNA topoisomerase III [Pseudomonas mediterranea].	38.10	399	234	5	56	454	262	647	2e-84	284
rs:WP_047458563	DNA topoisomerase III [Vibrio furnissii].	38.71	403	233	2	36	438	255	643	2e-84	284
rs:WP_027015253	DNA topoisomerase III [Comamonas composti].	37.37	396	237	4	61	454	267	653	2e-84	285
rs:WP_033884893	DNA topoisomerase III [Escherichia coli].	39.05	420	238	5	36	450	242	648	2e-84	285
rs:WP_024213397	DNA topoisomerase III [Escherichia coli].	39.05	420	238	5	36	450	242	648	2e-84	285
rs:WP_025818497	DNA topoisomerase III [Vibrio parahaemolyticus].	39.30	369	217	1	36	404	255	616	2e-84	284
rs:WP_007649355	DNA topoisomerase III [Shewanella sp. HN-41].	40.82	365	202	1	35	385	250	614	2e-84	285
rs:WP_020586452	DNA topoisomerase III [Desulfobacter curvatus].	36.93	482	237	10	32	459	239	707	2e-84	285
rs:WP_011267044	DNA topoisomerase III [Pseudomonas syringae].	39.67	426	240	6	31	452	236	648	2e-84	285
rs:WP_038913061	DNA topoisomerase III [Dickeya zeae].	37.98	416	248	4	36	450	242	648	2e-84	285
rs:WP_044705513	DNA topoisomerase III [Escherichia coli].	39.05	420	238	5	36	450	242	648	2e-84	285
rs:WP_024893297	DNA topoisomerase III [Acidithiobacillus thiooxidans].	41.45	427	226	8	29	445	243	655	2e-84	285
rs:WP_001175889	DNA topoisomerase III [Escherichia coli].	39.05	420	238	5	36	450	242	648	2e-84	285
rs:WP_004748460	DNA topoisomerase III [Vibrio tubiashii].	39.57	369	216	1	36	404	255	616	2e-84	284
rs:WP_042868977	DNA topoisomerase III [Dickeya sp. NCPPB 569].	37.74	416	249	4	36	450	242	648	2e-84	284
rs:WP_017184069	conjugal transfer protein TraE [Sphingobium xenophagum].	36.72	482	246	6	35	459	238	717	3e-84	285
rs:WP_007372580	DNA topoisomerase III [Kosakonia radicincitans].	39.47	418	237	7	36	450	242	646	3e-84	284
rs:WP_045498250	DNA topoisomerase III [Vibrio sp. 151112A].	39.57	369	216	1	36	404	255	616	3e-84	284
rs:WP_033948794	DNA topoisomerase III [Pseudomonas aeruginosa].	37.18	425	251	6	33	454	238	649	3e-84	284
rs:WP_031842635	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	41.77	328	184	1	58	385	1	321	3e-84	274
rs:WP_024533180	DNA topoisomerase III [Pseudomonas syringae].	39.20	426	242	6	31	452	236	648	3e-84	284
rs:WP_044340829	DNA topoisomerase III [Pseudomonas oryzihabitans].	39.09	417	243	5	36	450	241	648	3e-84	284
tr:A0A034TL34_9VIBR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	39.46	370	216	2	36	404	256	618	3e-84	283
rs:WP_017530155	DNA topoisomerase III [Pseudomonas fluorescens].	37.35	423	251	6	33	454	238	647	3e-84	283
rs:WP_024661467	DNA topoisomerase III [Pseudomonas syringae].	39.67	426	240	6	31	452	236	648	3e-84	284
rs:WP_046302819	DNA topoisomerase III [Grimontia sp. AD028].	41.19	369	210	3	36	404	251	612	3e-84	283
rs:WP_044187714	DNA topoisomerase III [Escherichia coli].	39.05	420	238	5	36	450	242	648	3e-84	284
tr:A0A090P8Q4_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	41.47	340	192	1	65	404	5	337	3e-84	275
rs:WP_044807771	DNA topoisomerase III [Escherichia coli].	39.05	420	238	5	36	450	242	648	4e-84	284
rs:WP_034054058	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	37.63	396	232	5	61	454	17	399	4e-84	276
rs:WP_045039898	DNA topoisomerase III [Photobacterium iliopiscarium].	40.85	355	209	1	32	386	247	600	4e-84	283
rs:WP_038265548	DNA topoisomerase III [Xenorhabdus cabanillasii].	36.40	445	257	6	18	450	213	643	4e-84	283
rs:WP_027857709	DNA topoisomerase III [Marinobacterium jannaschii].	40.79	380	216	3	36	414	251	622	4e-84	283
rs:WP_013660507	DNA topoisomerase III [Marinomonas mediterranea].	37.33	375	225	2	35	405	250	618	5e-84	283
rs:WP_039092690	DNA topoisomerase III [Gallibacterium anatis].	40.06	352	203	2	36	387	261	604	5e-84	283
rs:WP_004538149	DNA topoisomerase III [Burkholderia pseudomallei].	37.05	421	254	5	36	454	241	652	5e-84	283
rs:WP_044159002	MULTISPECIES: DNA topoisomerase III [Enterobacter].	39.71	418	236	7	36	450	242	646	6e-84	283
rs:WP_044175018	DNA topoisomerase III [Photobacterium damselae].	40.85	355	209	1	32	386	247	600	6e-84	282
rs:WP_027722150	DNA topoisomerase I [Desulfovibrio zosterae].	34.99	483	249	7	35	459	243	718	6e-84	285
rs:WP_005740008	DNA topoisomerase III [Pseudomonas amygdali].	38.68	424	247	5	31	452	236	648	6e-84	283
tr:A0A096FM68_COMTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	37.50	440	260	6	32	459	241	677	6e-84	285
rs:WP_034367860	hypothetical protein, partial [Comamonas testosteroni].	37.50	440	260	6	32	459	241	677	6e-84	285
tr:N9TX52_9GAMM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	39.79	387	225	2	36	420	249	629	6e-84	283
rs:WP_009876577	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	36.82	421	255	6	36	454	241	652	7e-84	283
rs:WP_011609880	DNA topoisomerase III [Histophilus somni].	38.04	418	238	7	36	450	245	644	7e-84	283
rs:WP_021555971	hypothetical protein [Escherichia coli].	39.90	416	240	5	36	450	242	648	7e-84	283
rs:WP_023912627	DNA topoisomerase III [Pseudomonas aeruginosa].	36.43	420	255	6	36	454	241	649	7e-84	283
rs:WP_034832080	DNA topoisomerase III [Endozoicomonas numazuensis].	39.28	387	225	4	32	417	247	624	7e-84	282
rs:WP_036206169	DNA topoisomerase III [Marinobacter sp. MCTG268].	37.02	470	241	9	35	459	253	712	7e-84	284
rs:WP_042048532	DNA topoisomerase III [Aeromonas simiae].	38.25	400	239	2	36	433	249	642	9e-84	282
rs:WP_024671564	DNA topoisomerase III [Pseudomonas syringae].	38.92	424	246	5	31	452	236	648	9e-84	283
rs:WP_003158613	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	37.37	396	237	4	61	454	267	653	1e-83	283
rs:WP_022965391	DNA topoisomerase III [Pseudomonas caeni].	40.17	351	207	1	36	386	251	598	1e-83	281
rs:WP_037404599	DNA topoisomerase III [Serratia sp. Ag2].	37.74	424	248	6	32	454	237	645	1e-83	282
rs:WP_012315136	MULTISPECIES: DNA topoisomerase III [Pseudomonas putida group].	37.24	427	253	7	29	454	233	645	1e-83	282
rs:WP_034065554	DNA topoisomerase III [Pseudomonas aeruginosa].	37.37	396	237	4	61	454	267	653	1e-83	283
rs:WP_031592267	DNA topoisomerase III [Pantoea agglomerans].	39.42	416	240	7	36	450	242	646	1e-83	283
rs:WP_033539187	DNA topoisomerase III [Shewanella sp. ECSMB14101].	41.24	354	207	1	32	385	247	599	1e-83	283
rs:WP_040031775	DNA topoisomerase III [Pectobacterium carotovorum].	36.26	455	268	7	6	459	221	654	1e-83	282
rs:WP_023124708	hypothetical protein [Pseudomonas aeruginosa].	38.38	396	229	5	61	454	267	649	1e-83	282
rs:WP_038182493	DNA topoisomerase III [Xenorhabdus bovienii].	36.40	445	255	6	18	450	213	641	1e-83	282
rs:WP_046162109	DNA topoisomerase III [Pseudomonas sp. 10B238].	39.53	387	231	2	23	408	229	613	1e-83	282
rs:WP_042176628	DNA topoisomerase III [Pseudomonas aeruginosa].	37.37	396	237	4	61	454	267	653	1e-83	282
rs:WP_039836674	DNA topoisomerase III [Vibrio rumoiensis].	39.57	369	219	1	36	404	258	622	1e-83	282
rs:WP_045969231	DNA topoisomerase III [Xenorhabdus doucetiae].	39.09	394	228	5	60	452	267	649	2e-83	282
rs:WP_015056502	DNA topoisomerase III [Erwinia amylovora].	39.42	416	240	7	36	450	242	646	2e-83	282
rs:WP_038220810	DNA topoisomerase III [Xenorhabdus nematophila].	36.18	445	258	6	18	450	213	643	2e-83	281
rs:WP_038194406	DNA topoisomerase III [Xenorhabdus bovienii].	38.22	416	244	4	36	450	242	645	2e-83	281
rs:WP_009372245	DNA topoisomerase III [Veillonella sp. oral taxon 780].	36.76	457	263	10	19	452	230	683	2e-83	284
rs:WP_016475404	DNA topoisomerase III [Veillonella sp. HPA0037].	37.39	476	255	12	19	454	230	702	2e-83	284
rs:WP_032629416	DNA topoisomerase III [Pseudomonas syringae].	37.83	423	252	6	29	450	234	646	2e-83	281
rs:WP_021018801	DNA topoisomerase III [Vibrio gazogenes].	41.69	367	203	4	36	399	255	613	2e-83	281
rs:WP_003120035	DNA topoisomerase III [Pseudomonas aeruginosa].	38.13	396	230	5	61	454	267	649	2e-83	281
rs:WP_032211070	DNA topoisomerase III [Escherichia coli].	38.57	420	240	5	36	450	242	648	2e-83	282
rs:WP_003474339	DNA topoisomerase III [Xanthomonas translucens].	36.95	433	261	5	23	454	228	649	2e-83	281
tr:A0A077PMV3_XENBV	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	38.22	416	244	4	36	450	246	649	2e-83	281
tr:A0A068QPA2_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	39.09	394	228	5	60	452	273	655	2e-83	281
rs:WP_038255203	DNA topoisomerase III [Xenorhabdus bovienii].	36.18	445	261	6	18	450	213	646	2e-83	281
rs:WP_033864034	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	36.79	424	254	6	36	454	139	553	3e-83	279
rs:WP_001562956	DNA topoisomerase III [Escherichia coli].	38.81	420	239	5	36	450	242	648	3e-83	282
tr:A0A0A1GLH5_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	39.28	387	232	2	23	408	230	614	3e-83	281
rs:WP_044833425	DNA topoisomerase III [Thalassomonas actiniarum].	39.89	376	221	2	28	399	243	617	3e-83	281
rs:WP_038172978	DNA topoisomerase III [Vibrio pacinii].	39.30	369	217	1	36	404	255	616	3e-83	281
rs:WP_024109633	MULTISPECIES: DNA topoisomerase III [Dickeya].	38.63	422	245	7	36	455	241	650	3e-83	281
rs:WP_045429170	DNA topoisomerase III [Pseudomonas sp. MT-1].	39.28	387	232	2	23	408	229	613	3e-83	281
rs:WP_038256049	DNA topoisomerase III [Xenorhabdus bovienii].	38.22	416	244	4	36	450	242	645	3e-83	281
rs:WP_039016632	MULTISPECIES: DNA topoisomerase III [Burkholderiaceae].	36.73	422	251	6	36	454	241	649	3e-83	281
tr:A0A090R3W2_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	39.60	351	205	1	35	385	1	344	3e-83	273
rs:WP_028470948	DNA topoisomerase III [Neptunomonas japonica].	41.91	346	197	1	35	376	250	595	3e-83	281
rs:WP_012768236	MULTISPECIES: DNA topoisomerase III [Dickeya].	37.09	399	240	5	61	459	267	654	3e-83	281
rs:WP_031804216	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	36.79	424	254	6	36	454	157	571	3e-83	279
rs:WP_033947838	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	36.43	431	257	6	33	459	238	655	4e-83	281
rs:WP_031762110	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	36.79	424	254	6	36	454	168	582	4e-83	280
rs:WP_023931617	DNA topoisomerase III [Photobacterium leiognathi].	41.69	343	199	1	32	374	247	588	4e-83	280
rs:WP_004252369	DNA topoisomerase III [Proteus mirabilis].	38.35	425	246	8	36	454	242	656	4e-83	281
rs:WP_047783271	DNA topoisomerase III [Variovorax paradoxus].	36.26	422	253	7	36	454	241	649	4e-83	281
rs:WP_027959218	MULTISPECIES: DNA topoisomerase III [Halomonas].	38.06	381	233	1	35	415	250	627	4e-83	280
rs:WP_033972349	DNA topoisomerase III [Pseudomonas aeruginosa].	36.32	424	258	5	32	454	237	649	4e-83	281
rs:WP_017707803	DNA topoisomerase III [Pseudomonas syringae].	38.50	426	245	6	31	452	236	648	5e-83	281
rs:WP_009618204	DNA topoisomerase III [Pseudomonas sp. M1].	36.79	424	257	6	32	454	237	650	5e-83	281
rs:WP_016355620	DNA topoisomerase [Pseudomonas migulae].	38.48	382	222	5	31	399	256	637	5e-83	285
rs:WP_042147566	DNA topoisomerase III [Pseudoalteromonas sp. '520P1 No. 412'].	41.60	351	196	1	35	385	258	599	5e-83	280
rs:WP_048255720	DNA topoisomerase III [Pectobacterium carotovorum].	35.82	455	270	7	6	459	221	654	5e-83	281
rs:WP_023124357	hypothetical protein [Pseudomonas aeruginosa].	35.80	433	267	7	23	454	228	650	5e-83	281
rs:WP_034014014	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	38.80	384	222	5	75	454	1	375	5e-83	273
tr:F3GHG4_PSESJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	41.03	368	201	5	88	452	1	355	5e-83	272
rs:WP_011716543	DNA topoisomerase III [Shewanella sp. ANA-3].	39.39	363	208	1	35	385	250	612	5e-83	281
rs:WP_027601788	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	39.47	418	240	6	36	450	241	648	5e-83	281
rs:WP_034006787	DNA topoisomerase III [Pseudomonas aeruginosa].	36.32	424	258	5	32	454	237	649	5e-83	281
tr:V1XDB5_SALMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	37.68	422	246	5	36	450	90	501	6e-83	276
rs:WP_024890123	DNA topoisomerase III [Luteimonas huabeiensis].	36.73	422	251	7	36	454	241	649	6e-83	280
rs:WP_004534801	DNA topoisomerase III [Burkholderia pseudomallei].	36.82	421	255	5	36	454	241	652	6e-83	281
rs:WP_044838231	DNA topoisomerase III [Thalassomonas viridans].	40.28	355	207	2	35	385	250	603	6e-83	280
rs:WP_027705174	DNA topoisomerase III [Zymobacter palmae].	40.96	354	206	1	32	385	247	597	6e-83	280
rs:WP_046461889	DNA topoisomerase III [Comamonas testosteroni].	37.27	440	261	6	32	459	241	677	7e-83	282
rs:WP_037040786	DNA topoisomerase III [Pseudomonas sp. BAY1663].	35.80	433	267	7	23	454	228	650	7e-83	280
rs:WP_036941675	DNA topoisomerase III [Providencia stuartii].	37.65	425	249	7	36	454	242	656	7e-83	281
rs:WP_041335167	DNA topoisomerase III [Marinobacter salarius].	36.81	470	242	9	35	459	253	712	7e-83	281
rs:WP_013185201	DNA topoisomerase III [Xenorhabdus nematophila].	36.18	445	258	6	18	450	213	643	7e-83	280
rs:WP_016807975	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	41.01	417	232	7	36	450	242	646	7e-83	280
rs:WP_011633249	DNA topoisomerase III [Nitrosomonas eutropha].	37.24	427	251	7	32	454	237	650	8e-83	280
rs:WP_039143633	DNA topoisomerase III [Gallibacterium anatis].	39.44	355	207	2	36	390	261	607	8e-83	280
rs:WP_039174200	DNA topoisomerase III [Gallibacterium genomosp. 1].	39.44	355	207	2	36	390	261	607	8e-83	280
rs:WP_003296453	DNA topoisomerase III [Pseudomonas stutzeri].	36.51	430	258	6	33	459	238	655	8e-83	280
tr:L1PX80_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	37.39	476	255	12	19	454	237	709	9e-83	282
rs:WP_029484957	DNA topoisomerase III [Enterobacter mori].	37.05	421	250	6	36	452	241	650	1e-82	280
rs:WP_034037691	DNA topoisomerase III [Pseudomonas aeruginosa].	35.80	433	267	7	23	454	228	650	1e-82	280
rs:WP_007160882	DNA topoisomerase III [Pseudomonas psychrotolerans].	39.57	417	241	5	36	450	241	648	1e-82	280
rs:WP_038148583	DNA topoisomerase [Veillonella atypica].	37.39	476	255	12	19	454	230	702	1e-82	282
rs:WP_016488058	DNA topoisomerase III [Pseudomonas putida].	38.55	428	242	9	36	459	240	650	1e-82	280
rs:WP_042323003	DNA topoisomerase III [Burkholderia ginsengisoli].	36.34	421	257	6	35	454	240	650	1e-82	280
rs:WP_047100582	DNA topoisomerase III [Dickeya dianthicola].	38.39	422	246	7	36	455	241	650	1e-82	280
rs:WP_019844491	DNA topoisomerase III [Dickeya zeae].	37.37	396	233	5	61	454	267	649	1e-82	280
rs:WP_046337374	DNA topoisomerase III [Xenorhabdus bovienii].	38.00	421	247	5	36	455	242	649	1e-82	280
rs:WP_010835677	DNA topoisomerase III [Salmonella enterica].	38.13	417	244	4	36	450	242	646	1e-82	280
rs:WP_034394054	hypothetical protein, partial [Comamonas testosteroni].	37.27	440	261	6	32	459	241	677	1e-82	281
rs:WP_031652706	DNA topoisomerase III [Pseudomonas aeruginosa].	37.03	424	253	6	36	454	241	655	1e-82	280
rs:WP_041013371	DNA topoisomerase III [Pseudomonas xanthomarina].	39.00	400	224	6	61	452	266	653	1e-82	280
tr:A0A0E3BV48_COMTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	37.27	440	261	6	32	459	241	677	1e-82	281
rs:WP_047540734	DNA topoisomerase III, partial [Shewanella sp. ZOR0012].	38.86	368	208	2	35	385	150	517	1e-82	278
rs:WP_038203143	DNA topoisomerase III [Xenorhabdus bovienii].	37.50	416	245	4	36	450	242	643	1e-82	280
rs:WP_047351293	DNA topoisomerase III [Diaphorobacter sp. J5-51].	36.26	422	253	6	36	454	241	649	1e-82	280
rs:WP_023103931	hypothetical protein [Pseudomonas aeruginosa].	36.08	424	259	5	32	454	237	649	1e-82	280
rs:WP_004255068	DNA topoisomerase III [Thauera sp. 63].	37.35	423	248	8	36	454	241	650	1e-82	280
rs:WP_000765274	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	38.12	425	247	8	36	454	242	656	1e-82	280
rs:WP_006789974	DNA topoisomerase [Anaeroglobus geminatus].	40.75	427	234	9	30	452	238	649	2e-82	280
rs:WP_037440394	DNA topoisomerase III, partial [Shewanella sp. YQH10].	36.91	401	250	2	36	435	254	652	2e-82	279
rs:WP_040031623	DNA topoisomerase III [Pectobacterium carotovorum].	36.60	429	252	6	36	459	241	654	2e-82	280
rs:WP_032214913	DNA topoisomerase III, partial [Escherichia coli].	39.42	416	242	5	36	450	242	648	2e-82	279
tr:A0A0A8RP43_PSEAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	36.79	424	254	6	36	454	241	655	2e-82	280
rs:WP_011622216	DNA topoisomerase III [Shewanella sp. MR-4].	39.12	363	209	1	35	385	250	612	2e-82	280
rs:WP_010846448	DNA topoisomerase [Xenorhabdus nematophila].	36.78	416	250	5	36	450	242	645	2e-82	280
rs:WP_025202529	DNA topoisomerase III [Aeromonas hydrophila].	38.93	411	231	7	36	435	249	650	2e-82	279
rs:WP_032963652	DNA topoisomerase III [Bordetella hinzii].	37.03	424	256	7	32	454	237	650	2e-82	279
rs:WP_046336289	DNA topoisomerase III [Xenorhabdus bovienii].	37.74	416	244	4	36	450	242	643	2e-82	279
rs:WP_047634653	DNA topoisomerase III [Escherichia coli].	38.57	420	240	5	36	450	242	648	2e-82	280
rs:WP_015851562	DNA topoisomerase type IA central domain-containing protein [Desulfovibrio salexigens].	34.02	485	257	4	31	459	238	715	2e-82	280
rs:WP_023098549	hypothetical protein [Pseudomonas aeruginosa].	36.79	424	254	6	36	454	241	655	2e-82	279
rs:WP_021462028	DNA topoisomerase III [Gallibacterium anatis].	38.55	358	212	2	36	392	244	594	2e-82	278
rs:WP_004239734	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	37.65	425	249	7	36	454	242	656	2e-82	280
rs:WP_033937544	DNA topoisomerase III [Pseudomonas aeruginosa].	37.05	421	250	6	36	452	241	650	2e-82	279
rs:WP_031204974	DNA topoisomerase III, partial [Gallibacterium anatis].	38.55	358	212	2	36	392	244	594	2e-82	277
rs:WP_003116834	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	36.79	424	254	6	36	454	241	655	2e-82	279
rs:WP_029578156	DNA topoisomerase III [Bordetella hinzii].	37.70	427	249	8	32	454	237	650	2e-82	279
rs:WP_012988057	DNA topoisomerase III [Xenorhabdus bovienii].	37.26	416	246	5	36	450	242	643	2e-82	279
rs:WP_003098974	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	36.79	424	254	6	36	454	241	655	2e-82	279
rs:WP_033992584	DNA topoisomerase III [Pseudomonas aeruginosa].	36.79	424	254	6	36	454	241	655	2e-82	279
rs:WP_023102544	hypothetical protein [Pseudomonas aeruginosa].	37.05	421	250	6	36	452	241	650	2e-82	279
rs:WP_041416793	DNA topoisomerase III [Shewanella sp. MR-7].	39.12	363	209	1	35	385	250	612	2e-82	280
rs:WP_004245767	DNA topoisomerase III [Proteus mirabilis].	37.88	425	248	8	36	454	242	656	2e-82	279
rs:WP_020361462	DNA topoisomerase III [Pseudomonas syringae].	37.71	419	248	5	36	452	241	648	2e-82	279
rs:WP_034044103	DNA topoisomerase III [Pseudomonas aeruginosa].	36.79	424	254	6	36	454	241	655	2e-82	279
rs:WP_039660108	DNA topoisomerase III [Pantoea sp. MBLJ3].	40.74	351	205	1	35	385	250	597	2e-82	278
rs:WP_042197545	DNA topoisomerase III [Escherichia coli].	37.65	425	249	7	36	454	242	656	2e-82	279
rs:WP_027709546	DNA topoisomerase III [Zooshikella ganghwensis].	38.40	388	218	2	36	403	251	637	2e-82	279
rs:WP_034022471	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	36.79	424	254	6	36	454	241	655	3e-82	279
rs:WP_043081838	DNA topoisomerase III [Pluralibacter gergoviae].	37.05	421	250	6	36	452	241	650	3e-82	279
rs:WP_033955185	DNA topoisomerase III [Pseudomonas aeruginosa].	36.79	424	254	6	36	454	241	655	3e-82	279
tr:A0A0B6X684_XENBV	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	37.74	416	244	4	36	450	251	652	3e-82	279
rs:WP_016253291	MULTISPECIES: hypothetical protein [Proteobacteria].	38.76	387	222	5	70	454	276	649	3e-82	279
rs:WP_014424541	topoisomerase III [Selenomonas ruminantium].	36.42	453	249	10	24	459	231	661	3e-82	281
rs:WP_032095057	MULTISPECIES: DNA topoisomerase III [Alteromonas].	37.85	391	231	4	32	410	247	637	3e-82	278
rs:WP_010846407	DNA topoisomerase III [Xenorhabdus nematophila].	38.46	416	243	4	36	450	242	645	3e-82	278
rs:WP_009459717	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	36.19	420	256	5	36	454	241	649	3e-82	279
rs:WP_025513247	DNA topoisomerase III [Bordetella trematum].	36.56	424	258	7	32	454	237	650	3e-82	279
rs:WP_017787114	DNA topoisomerase III [Aeromonas hydrophila].	40.05	382	217	5	36	414	249	621	3e-82	278
rs:WP_042907580	DNA topoisomerase III [Gallibacterium anatis].	39.15	355	208	2	36	390	261	607	3e-82	278
rs:WP_046337887	DNA topoisomerase III, partial [Xenorhabdus bovienii].	39.51	367	202	4	91	455	1	349	3e-82	270
rs:WP_005381063	MULTISPECIES: DNA topoisomerase [Veillonella].	37.18	476	256	12	19	454	230	702	3e-82	281
rs:WP_046984497	DNA topoisomerase III [Thermomonas brevis].	36.68	428	257	6	32	454	237	655	3e-82	279
rs:WP_023095522	hypothetical protein [Pseudomonas aeruginosa].	37.63	396	232	5	61	454	267	649	3e-82	278
rs:WP_037430092	DNA topoisomerase III [Shewanella sp. POL2].	39.13	368	207	2	35	385	250	617	4e-82	279
rs:WP_042483778	DNA topoisomerase III [Vibrio diazotrophicus].	39.57	369	216	1	36	404	255	616	4e-82	278
rs:WP_047656105	DNA topoisomerase III [Escherichia coli].	39.18	416	243	5	36	450	242	648	4e-82	278
rs:WP_023267714	DNA topoisomerase III [Shewanella decolorationis].	39.12	363	209	1	35	385	250	612	4e-82	279
tr:Q0HWK8_SHESR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	39.12	363	209	1	35	385	275	637	4e-82	280
rs:WP_037420090	DNA topoisomerase III [Shewanella xiamenensis].	39.13	368	207	2	35	385	250	617	4e-82	280
rs:WP_042997240	DNA topoisomerase III, partial [Bordetella bronchiseptica].	37.63	396	232	5	61	454	267	649	4e-82	278
rs:WP_020651207	DNA topoisomerase III [Solimonas variicoloris].	37.47	427	250	8	32	454	237	650	4e-82	278
rs:WP_010635840	DNA topoisomerase III [Aeromonas dhakensis].	40.05	382	217	5	36	414	249	621	4e-82	278
rs:WP_012205960	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	36.73	422	251	6	36	454	241	649	4e-82	278
rs:WP_031635081	DNA topoisomerase III [Pseudomonas aeruginosa].	37.00	427	252	7	32	454	237	650	4e-82	278
rs:WP_044202797	DNA topoisomerase III [Pectobacterium carotovorum].	36.00	425	260	5	36	459	241	654	4e-82	278
rs:WP_034000341	DNA topoisomerase III [Pseudomonas aeruginosa].	36.73	422	251	6	36	454	241	649	4e-82	278
rs:WP_043597926	DNA topoisomerase III [Aeromonas diversa].	39.53	387	226	2	36	420	249	629	4e-82	278
rs:WP_025920348	DNA topoisomerase III [Pectobacterium wasabiae].	36.04	444	258	7	21	459	232	654	4e-82	278
rs:WP_015879466	DNA topoisomerase III [Tolumonas auensis].	36.51	430	258	6	33	459	238	655	4e-82	278
rs:WP_012248046	DNA topoisomerase III [Bordetella petrii].	37.37	396	233	5	61	454	267	649	4e-82	278
rs:WP_046336194	DNA topoisomerase III [Xenorhabdus bovienii].	35.28	445	264	5	18	450	213	645	4e-82	278
rs:WP_017053489	DNA topoisomerase III [Vibrio genomosp. F6].	39.30	369	217	1	36	404	255	616	4e-82	278
rs:WP_046557200	DNA topoisomerase III [Arsukibacterium ikkense].	39.15	355	211	1	36	385	251	605	5e-82	278
rs:WP_038472828	DNA topoisomerase III, partial [Acidithiobacillus caldus].	42.78	374	194	8	31	399	224	582	5e-82	276
rs:WP_009660877	DNA topoisomerase III [Veillonella sp. ACP1].	37.39	476	255	12	19	454	230	702	5e-82	280
rs:WP_044293632	DNA topoisomerase III [Pseudomonas amygdali].	39.62	424	243	5	31	452	236	648	5e-82	278
rs:WP_014606859	DNA topoisomerase III [Pantoea ananatis].	37.71	419	245	7	36	450	242	648	5e-82	278
rs:WP_024008203	DNA topoisomerase III [Pseudomonas aeruginosa].	36.08	424	259	5	32	454	237	649	5e-82	278
rs:WP_042050123	DNA topoisomerase III [Aeromonas dhakensis].	40.05	382	217	5	36	414	249	621	5e-82	278
rs:WP_011804699	DNA topoisomerase III [Acidovorax sp. JS42].	37.63	396	232	5	61	454	267	649	5e-82	278
tr:A0A0B6X433_XENBV	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	35.28	445	264	5	18	450	219	651	5e-82	278
rs:WP_007151773	DNA topoisomerase III [Marinobacter algicola].	35.97	467	250	6	35	459	253	712	5e-82	279
tr:F9ZNS5_ACICS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	40.61	426	228	10	31	445	235	646	5e-82	280
rs:WP_017072510	DNA topoisomerase III [Vibrio splendidus].	39.57	369	218	1	36	404	255	618	5e-82	278
rs:WP_016793847	DNA topoisomerase III [Vibrio cyclitrophicus].	39.57	369	218	1	36	404	255	618	5e-82	278
rs:WP_040528706	DNA topoisomerase III [Grimontia hollisae].	41.69	355	200	3	36	390	251	598	6e-82	277
rs:WP_034017287	DNA topoisomerase III [Pseudomonas aeruginosa].	37.63	396	232	5	61	454	267	649	6e-82	278
rs:WP_023093469	MULTISPECIES: hypothetical protein [Gammaproteobacteria].	35.80	433	264	6	25	454	228	649	6e-82	278
rs:WP_031764334	DNA topoisomerase III [Pseudomonas aeruginosa].	37.94	398	234	5	61	454	267	655	6e-82	278
rs:WP_042583917	DNA topoisomerase III [Burkholderia sp. MSHR3999].	36.58	421	256	5	36	454	241	652	6e-82	278
rs:WP_028690960	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	35.85	424	260	5	32	454	237	649	7e-82	278
rs:WP_046803444	DNA topoisomerase III [Achromobacter sp. LC458].	36.58	421	256	5	36	454	241	652	7e-82	278
rs:WP_039139562	DNA topoisomerase III, partial [Gallibacterium anatis].	38.64	352	208	2	36	387	64	407	7e-82	272
rs:WP_018346753	DNA topoisomerase III [Gallibacterium anatis].	39.49	352	205	2	36	387	261	604	7e-82	277
rs:WP_047440339	DNA topoisomerase III [Aeromonas sp. ZOR0001].	38.95	380	222	3	36	412	249	621	7e-82	277
rs:WP_045048080	DNA topoisomerase III [Rouxiella chamberiensis].	40.17	351	207	1	35	385	250	597	7e-82	277
rs:WP_047678799	DNA topoisomerase III [Xenorhabdus sp. NBAII XenSa04].	38.92	424	242	6	36	455	242	652	7e-82	278
rs:WP_023101001	hypothetical protein [Pseudomonas aeruginosa].	36.73	422	253	5	36	452	241	653	7e-82	278
rs:WP_017089851	DNA topoisomerase III [Vibrio splendidus].	39.57	369	218	1	36	404	255	618	8e-82	277
rs:WP_014699279	DNA topoisomerase [Pectobacterium sp. SCC3193].	36.13	429	254	6	36	459	241	654	8e-82	278
rs:WP_038216568	DNA topoisomerase III [Xenorhabdus bovienii].	37.26	416	246	4	36	450	242	643	8e-82	277
rs:WP_005306353	MULTISPECIES: DNA topoisomerase III [Aeromonas].	39.79	382	218	4	36	414	249	621	8e-82	277
rs:WP_021205167	DNA topoisomerase III [Pseudomonas aeruginosa].	36.49	422	252	6	36	454	241	649	9e-82	278
rs:WP_019823776	DNA topoisomerase III [Vibrio splendidus].	39.57	369	218	1	36	404	255	618	9e-82	277
rs:WP_017640402	DNA topoisomerase III [Pseudomonas sp. 313].	37.06	394	237	4	61	454	267	649	9e-82	277
rs:WP_034037945	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	36.77	427	253	7	32	454	92	505	9e-82	274
rs:WP_026383892	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	37.88	396	231	5	61	454	267	649	9e-82	277
rs:WP_017779312	DNA topoisomerase III [Aeromonas hydrophila].	40.43	371	210	4	36	403	249	611	9e-82	277
rs:WP_013795485	DNA topoisomerase III [Marinomonas posidonica].	39.60	351	207	1	35	385	250	595	1e-81	277
rs:WP_003108987	DNA topoisomerase III [Pseudomonas aeruginosa].	36.56	424	255	6	36	454	241	655	1e-81	277
rs:WP_016792776	DNA topoisomerase III [Vibrio cyclitrophicus].	39.57	369	218	1	36	404	255	618	1e-81	277
rs:WP_036562672	DNA topoisomerase III, partial [Candidatus Schmidhempelia bombi].	38.50	361	222	0	36	396	251	611	1e-81	276
tr:D0I730_GRIHO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	41.69	355	200	3	36	390	272	619	1e-81	277
rs:WP_011072959	DNA topoisomerase III [Shewanella oneidensis].	39.40	368	207	3	32	385	247	612	1e-81	278
rs:WP_034691397	DNA topoisomerase III [Acidovorax sp. MR-S7].	37.63	396	232	5	61	454	267	649	1e-81	277
rs:WP_035815289	hypothetical protein, partial [Cupriavidus basilensis].	40.84	431	244	7	33	454	238	666	1e-81	277
rs:WP_020913174	DNA topoisomerase III [Shewanella piezotolerans].	35.91	401	254	2	32	429	247	647	1e-81	277
rs:WP_010437081	MULTISPECIES: DNA topoisomerase III [Vibrio].	39.57	369	218	1	36	404	255	618	1e-81	277
rs:WP_032470230	DNA topoisomerase III [Vibrio cholerae].	41.40	343	192	3	35	374	255	591	1e-81	277
rs:WP_011804749	DNA topoisomerase III [Acidovorax sp. JS42].	37.37	396	233	5	61	454	267	649	1e-81	277
rs:WP_021183047	DNA topoisomerase III [Pantoea sp. AS-PWVM4].	41.14	350	198	3	36	385	251	592	1e-81	276
rs:WP_003290179	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	36.97	422	250	6	36	454	241	649	1e-81	277
rs:WP_023657257	DNA topoisomerase III [Pseudomonas aeruginosa].	35.61	424	261	5	32	454	237	649	1e-81	277
rs:WP_012154870	DNA topoisomerase III [Shewanella pealeana].	38.10	357	218	1	32	385	247	603	1e-81	277
rs:WP_040277052	DNA topoisomerase III [Xanthomonas citri].	37.00	400	237	5	61	458	267	653	1e-81	277
rs:WP_043170626	MULTISPECIES: DNA topoisomerase III [Aeromonas].	39.79	382	218	5	36	414	249	621	1e-81	276
rs:WP_034007122	DNA topoisomerase III [Pseudomonas aeruginosa].	36.58	421	252	6	36	452	241	650	2e-81	277
rs:WP_041214278	DNA topoisomerase III [Aeromonas caviae].	40.57	350	201	2	36	385	249	591	2e-81	277
rs:WP_017785618	DNA topoisomerase III [Aeromonas hydrophila].	39.79	382	218	5	36	414	249	621	2e-81	276
rs:WP_035015800	DNA topoisomerase III [Catenovulum agarivorans].	39.39	358	209	2	36	386	249	605	2e-81	277
rs:WP_017111130	DNA topoisomerase III [Vibrio tasmaniensis].	39.30	369	219	1	36	404	255	618	2e-81	276
rs:WP_046856132	DNA topoisomerase III [Pseudomonas sp. CCOS191].	37.59	423	243	9	36	454	240	645	2e-81	276
rs:WP_043125882	DNA topoisomerase III [Aeromonas hydrophila].	39.02	410	231	7	36	435	249	649	2e-81	276
rs:WP_043223335	DNA topoisomerase III [Bordetella hinzii].	36.30	427	255	6	32	454	237	650	2e-81	276
rs:WP_020230133	DNA topoisomerase III [Acidovorax sp. MR-S7].	37.63	396	232	5	61	454	292	674	2e-81	277
rs:WP_033135309	DNA topoisomerase III [Aeromonas finlandiensis].	38.79	379	224	2	36	412	249	621	2e-81	276
rs:WP_028768377	DNA topoisomerase III [Shewanella fidelis].	38.66	357	216	1	32	385	247	603	2e-81	276
rs:WP_046218684	DNA topoisomerase III [Photobacterium halotolerans].	37.67	369	225	1	36	404	251	614	2e-81	276
rs:WP_039525738	DNA topoisomerase III [Pectobacterium carotovorum].	37.09	399	240	4	61	459	267	654	2e-81	276
rs:WP_017033131	DNA topoisomerase III [Vibrio genomosp. F10].	39.57	369	218	1	36	404	255	618	2e-81	276
rs:WP_006005546	DNA topoisomerase III [Glaciecola punicea].	39.71	350	202	1	36	385	251	591	2e-81	276
rs:WP_009381396	DNA topoisomerase [Megasphaera genomosp. type_1].	39.20	426	235	9	29	450	238	643	2e-81	278
rs:WP_010215518	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	38.68	424	247	5	31	452	128	540	2e-81	274
rs:WP_007469989	DNA topoisomerase III [Photobacterium sp. AK15].	40.29	350	204	1	36	385	251	595	2e-81	276
rs:WP_006070054	DNA topoisomerase III [Vibrio shilonii].	40.11	369	214	2	36	404	255	616	2e-81	276
rs:WP_040264327	DNA topoisomerase III [Serratia symbiotica].	38.85	417	241	6	36	450	242	646	2e-81	276
rs:WP_045788841	DNA topoisomerase III [Aeromonas hydrophila].	38.69	411	232	7	36	435	249	650	2e-81	276
rs:WP_031592645	DNA topoisomerase III [Pantoea agglomerans].	38.00	421	241	8	36	450	242	648	2e-81	276
rs:WP_042016249	DNA topoisomerase III [Aeromonas caviae].	40.57	350	201	2	36	385	249	591	2e-81	276
rs:WP_023434592	DNA topoisomerase III [Pseudomonas aeruginosa].	36.53	427	254	8	32	454	237	650	3e-81	276
rs:WP_036549645	DNA topoisomerase III [Nitrincola lacisaponensis].	40.46	351	206	1	35	385	251	598	3e-81	276
rs:WP_017012090	DNA topoisomerase III [Enterovibrio calviensis].	40.11	369	214	3	36	404	251	612	3e-81	276
rs:WP_017080912	DNA topoisomerase III [Vibrio splendidus].	39.30	369	219	1	36	404	255	618	3e-81	276
rs:WP_007391353	DNA topoisomerase [Megasphaera sp. UPII 199-6].	39.20	426	235	9	29	450	238	643	3e-81	277
rs:WP_004666758	DNA topoisomerase III [Pseudomonas savastanoi].	38.22	382	223	5	31	399	256	637	3e-81	280
rs:WP_009835356	DNA topoisomerase III [Marinomonas sp. MED121].	34.81	405	244	2	35	439	250	634	3e-81	276
rs:WP_024894057	DNA topoisomerase III [Acidithiobacillus thiooxidans].	39.81	432	233	9	31	447	232	651	3e-81	276
rs:WP_044321331	DNA topoisomerase III [Pseudomonas amygdali].	39.23	390	223	5	65	454	271	646	3e-81	276
rs:WP_005730106	DNA topoisomerase III [Pseudomonas amygdali].	38.73	426	244	6	31	452	236	648	3e-81	276
rs:WP_004566591	dna topoisomerase ec=5.99.1.2 [Bordetella bronchiseptica].	37.63	396	232	5	61	454	267	649	3e-81	276
rs:WP_009848706	DNA topoisomerase III [Vibrio sp. MED222].	39.02	369	220	1	36	404	255	618	3e-81	276
rs:WP_043547201	DNA topoisomerase III [Pseudomonas aeruginosa].	35.33	433	269	7	23	454	228	650	3e-81	276
rs:WP_038201453	DNA topoisomerase III [Xenophilus azovorans].	37.34	399	236	4	61	454	267	656	3e-81	276
rs:WP_036161006	DNA topoisomerase III [Marinomonas ushuaiensis].	38.83	358	215	2	35	390	250	605	3e-81	276
rs:WP_016798141	DNA topoisomerase III [Vibrio cyclitrophicus].	39.57	369	218	1	36	404	255	618	3e-81	276
rs:WP_013052140	DNA topoisomerase III [Shewanella violacea].	37.85	391	237	2	32	417	247	636	3e-81	275
rs:WP_017095039	DNA topoisomerase III [Vibrio splendidus].	39.30	369	219	1	36	404	255	618	3e-81	276
rs:WP_017038719	DNA topoisomerase III [Vibrio genomosp. F10].	39.57	369	218	1	36	404	255	618	3e-81	276
rs:WP_017781182	DNA topoisomerase III [Aeromonas hydrophila].	40.16	371	211	4	36	403	249	611	3e-81	276
rs:WP_043294193	DNA topoisomerase III [Burkholderia pseudomallei].	37.35	423	250	6	36	454	241	652	3e-81	276
rs:WP_044345499	DNA topoisomerase III [Pseudomonas meliae].	38.73	426	244	6	31	452	236	648	3e-81	276
rs:WP_017092500	DNA topoisomerase III [Vibrio splendidus].	39.30	369	219	1	36	404	255	618	3e-81	275
rs:WP_017085070	DNA topoisomerase III [Vibrio splendidus].	39.30	369	219	1	36	404	255	618	3e-81	275
rs:WP_017084055	DNA topoisomerase III [Vibrio splendidus].	39.30	369	219	1	36	404	255	618	3e-81	275
rs:WP_039594020	DNA topoisomerase III [Pseudomonas frederiksbergensis].	36.41	423	257	5	33	452	238	651	3e-81	276
rs:WP_004734086	DNA topoisomerase III [Vibrio splendidus].	39.30	369	219	1	36	404	255	618	4e-81	276
tr:M4JXQ1_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	37.93	406	244	3	36	435	224	627	4e-81	275
rs:WP_041931602	DNA topoisomerase III [Pseudomonas poae].	37.93	406	244	3	36	435	241	644	4e-81	275
rs:WP_005378468	DNA topoisomerase [Veillonella atypica].	36.97	476	257	12	19	454	230	702	4e-81	278
rs:WP_016783801	DNA topoisomerase III [Vibrio cyclitrophicus].	39.30	369	219	1	36	404	255	618	4e-81	275
rs:WP_034021440	DNA topoisomerase III [Pseudomonas aeruginosa].	37.12	423	249	8	36	454	241	650	4e-81	276
rs:WP_034030437	DNA topoisomerase III [Pseudomonas aeruginosa].	37.63	396	232	5	61	454	267	649	4e-81	276
rs:WP_013721964	DNA topoisomerase III [Alicycliphilus denitrificans].	36.30	427	255	6	32	454	237	650	4e-81	276
rs:WP_021231452	DNA topoisomerase III [Aeromonas veronii].	38.79	379	224	2	36	412	249	621	4e-81	275
rs:WP_032972638	DNA topoisomerase III [Bordetella hinzii].	35.85	424	261	7	32	454	237	650	4e-81	276
rs:WP_021205487	DNA topoisomerase III [Pseudomonas aeruginosa].	37.00	427	252	8	32	454	237	650	4e-81	276
rs:WP_024889541	DNA topoisomerase III [Luteimonas huabeiensis].	36.84	418	253	5	36	452	241	648	4e-81	276
rs:WP_016352275	DNA topoisomerase III [Aeromonas hydrophila].	38.44	411	233	7	36	435	249	650	4e-81	275
rs:WP_017462946	DNA topoisomerase III [Dyella ginsengisoli].	36.64	423	251	8	36	454	241	650	5e-81	276
tr:V1WH61_SALMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	36.64	423	249	5	36	450	90	501	5e-81	272
rs:WP_031688162	DNA topoisomerase III [Pseudomonas aeruginosa].	36.08	424	260	7	32	454	237	650	5e-81	276
rs:WP_012584772	DNA topoisomerase III [Thauera sp. MZ1T].	36.64	423	251	8	36	454	241	650	5e-81	276
rs:WP_004281998	conjugal transfer protein TraE [Acinetobacter lwoffii].	34.45	447	269	6	24	459	229	662	5e-81	277
rs:WP_017059374	DNA topoisomerase III [Vibrio crassostreae].	39.30	369	219	1	36	404	255	618	5e-81	275
rs:WP_017070329	DNA topoisomerase III [Vibrio crassostreae].	39.02	369	220	1	36	404	255	618	5e-81	275
rs:WP_042657288	DNA topoisomerase III [Aeromonas allosaccharophila].	38.90	383	218	3	36	412	249	621	5e-81	275
rs:WP_047964038	DNA topoisomerase III [Xenorhabdus khoisanae].	37.03	424	250	6	36	455	242	652	5e-81	275
rs:WP_042864792	DNA topoisomerase III [Aeromonas hydrophila].	38.92	388	225	5	36	420	249	627	5e-81	275
rs:WP_011237227	DNA topoisomerase III [Aromatoleum aromaticum].	35.57	433	270	5	23	454	228	652	5e-81	275
rs:WP_017099216	DNA topoisomerase III [Vibrio tasmaniensis].	39.02	369	220	1	36	404	255	618	5e-81	275
rs:WP_023125205	hypothetical protein [Pseudomonas aeruginosa].	36.64	423	251	8	36	454	241	650	6e-81	275
rs:WP_008223266	DNA topoisomerase III [Vibrionales bacterium SWAT-3].	38.75	369	221	1	36	404	255	618	6e-81	275
rs:WP_039980581	DNA topoisomerase III [Vibrio sagamiensis].	39.02	369	218	1	36	404	255	616	6e-81	275
rs:WP_017107363	DNA topoisomerase III [Vibrio tasmaniensis].	39.30	369	219	1	36	404	255	618	6e-81	275
rs:WP_010206575	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	39.39	424	244	5	31	452	236	648	6e-81	275
rs:WP_032108805	DNA topoisomerase III [Haemophilus sp. FF7].	38.75	369	219	2	36	404	253	614	6e-81	275
rs:WP_012603511	DNA topoisomerase III [Vibrio tasmaniensis].	39.02	369	220	1	36	404	255	618	6e-81	275
rs:WP_009668885	DNA topoisomerase III [gamma proteobacterium IMCC1989].	37.79	389	222	3	35	404	257	644	6e-81	275
rs:WP_031653318	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	39.19	370	212	5	89	454	3	363	6e-81	267
rs:WP_015601729	DNA topoisomerase III family protein [Burkholderia thailandensis].	36.58	421	256	5	36	454	241	652	6e-81	275
rs:WP_011489283	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	36.26	422	253	6	36	454	241	649	7e-81	275
rs:WP_023443922	DNA topoisomerase III [Pseudomonas chloritidismutans].	36.88	423	250	8	36	454	241	650	7e-81	275
rs:WP_017040350	DNA topoisomerase III [Vibrio genomosp. F10].	39.30	369	219	1	36	404	255	618	7e-81	275
rs:WP_022579834	DNA topoisomerase III [Pseudomonas aeruginosa].	37.06	394	237	4	61	454	267	649	7e-81	275
rs:WP_042880354	DNA topoisomerase III [Aeromonas sp. ZOR0002].	40.29	350	202	2	36	385	249	591	8e-81	275
rs:WP_028685751	DNA topoisomerase III [Phaseolibacter flectens].	39.32	351	210	1	35	385	250	597	8e-81	274
rs:WP_005552801	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	38.75	369	219	2	36	404	259	620	8e-81	274
rs:WP_017079516	DNA topoisomerase III [Vibrio splendidus].	39.02	369	220	1	36	404	255	618	8e-81	275
rs:WP_020358329	DNA topoisomerase III [Pseudomonas syringae].	39.39	424	244	5	31	452	236	648	8e-81	275
rs:WP_017066255	DNA topoisomerase III [Vibrio crassostreae].	39.02	369	220	1	36	404	255	618	8e-81	275
rs:WP_023106356	hypothetical protein [Pseudomonas aeruginosa].	36.17	423	257	5	36	454	241	654	8e-81	275
rs:WP_041211922	DNA topoisomerase III [Aeromonas caviae].	39.02	387	224	5	36	419	249	626	8e-81	275
rs:WP_033990595	DNA topoisomerase III [Pseudomonas aeruginosa].	37.63	396	232	5	61	454	267	649	8e-81	275
tr:A0A0A5MQ36_AERCA	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	40.29	350	202	2	36	385	249	591	9e-81	275
rs:WP_043992340	DNA topoisomerase III, partial [Vibrio cholerae].	40.29	350	202	1	36	385	127	469	9e-81	271
rs:WP_039498870	DNA topoisomerase III [Pectobacterium carotovorum].	35.60	427	259	6	36	459	241	654	9e-81	275
rs:WP_046222677	DNA topoisomerase III [Vibrio sp. ECSMB14106].	39.30	369	219	1	36	404	255	618	9e-81	275
rs:WP_039041035	DNA topoisomerase III [Aeromonas caviae].	40.29	350	202	2	36	385	249	591	9e-81	275
rs:WP_045522780	DNA topoisomerase III [Aeromonas caviae].	40.29	350	202	2	36	385	249	591	9e-81	275
rs:WP_020798922	DNA topoisomerase III family protein [Pseudomonas sp. G5(2012)].	36.68	428	254	7	36	459	241	655	1e-80	275
rs:WP_017063444	DNA topoisomerase III [Vibrio crassostreae].	39.02	369	220	1	36	404	255	618	1e-80	275
rs:WP_020306649	DNA topoisomerase III [Pseudomonas syringae].	37.97	424	250	5	31	452	236	648	1e-80	275
rs:WP_028773045	DNA topoisomerase III [Shewanella waksmanii].	38.79	379	231	1	35	412	250	628	1e-80	275
rs:WP_048209504	DNA topoisomerase III [Aeromonas hydrophila].	40.29	350	202	2	36	385	249	591	1e-80	275
rs:WP_024691435	DNA topoisomerase III [Pseudomonas syringae].	38.21	424	249	5	31	452	236	648	1e-80	275
rs:WP_012723224	DNA topoisomerase III [Pseudomonas fluorescens].	36.41	423	255	6	33	454	238	647	1e-80	274
rs:WP_046027642	DNA topoisomerase III [Pseudomonas fluorescens].	37.35	407	236	4	36	436	241	634	1e-80	274
rs:WP_038229473	DNA topoisomerase III [Vibrio sp. ER1A].	40.11	369	214	2	36	404	255	616	1e-80	274
rs:WP_017104047	DNA topoisomerase III [Vibrio tasmaniensis].	39.02	369	220	1	36	404	255	618	1e-80	274
rs:WP_014291218	DNA topoisomerase III [Oceanimonas sp. GK1].	40.74	351	203	2	36	385	251	597	1e-80	274
rs:WP_023101516	hypothetical protein [Pseudomonas aeruginosa].	36.88	423	250	8	36	454	241	650	1e-80	275
rs:WP_017372945	DNA topoisomerase III [Enterobacteriaceae bacterium LSJC7].	39.89	371	211	4	36	404	251	611	1e-80	274
rs:WP_031632015	DNA topoisomerase III [Pseudomonas aeruginosa].	36.88	423	250	8	36	454	241	650	1e-80	275
rs:WP_010792172	DNA topoisomerase III [Pseudomonas aeruginosa].	35.85	424	261	7	32	454	237	650	1e-80	274
rs:WP_045331640	DNA topoisomerase III [Enterobacter cloacae].	39.95	383	222	3	29	409	232	608	1e-80	273
rs:WP_031755005	DNA topoisomerase III [Pseudomonas aeruginosa].	35.85	424	261	7	32	454	237	650	1e-80	274
rs:WP_039607434	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	38.92	424	246	5	31	452	236	648	1e-80	274
rs:WP_039032788	DNA topoisomerase III [Shewanella sp. ECSMB14102].	40.11	354	208	2	32	385	247	596	1e-80	275
rs:WP_039164205	DNA topoisomerase III [Gallibacterium anatis].	38.87	355	209	2	36	390	261	607	1e-80	274
tr:A0A0B6X7U4_XENBV	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	38.27	392	221	5	61	450	142	514	1e-80	271
rs:WP_003821061	MULTISPECIES: dna topoisomerase ec=5.99.1.2 [Proteobacteria].	38.21	390	226	5	67	454	273	649	1e-80	274
rs:WP_034065220	DNA topoisomerase III [Pseudomonas aeruginosa].	35.61	424	261	5	32	454	237	649	1e-80	274
rs:WP_021179591	DNA topoisomerase III [Serratia fonticola].	37.22	395	235	5	57	449	262	645	1e-80	274
rs:WP_010846535	DNA topoisomerase III [Xenorhabdus nematophila].	35.73	445	260	6	18	450	213	643	1e-80	274
rs:WP_034058298	DNA topoisomerase III [Pseudomonas aeruginosa].	36.71	425	254	7	36	454	241	656	1e-80	275
rs:WP_005566047	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	38.75	369	219	2	36	404	259	620	1e-80	274
rs:WP_017099417	DNA topoisomerase III [Vibrio tasmaniensis].	39.30	369	219	1	36	404	255	618	1e-80	274
tr:A0A0E9L7X4_9BURK	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAO21682.1};	37.00	427	252	7	32	454	237	650	1e-80	274
rs:WP_024945198	DNA topoisomerase III [Aeromonas hydrophila].	38.20	411	234	7	36	435	249	650	2e-80	274
rs:WP_008265951	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	37.37	396	233	5	61	454	267	649	2e-80	274
rs:WP_005966930	MULTISPECIES: DNA topoisomerase III [Pectobacterium].	36.66	401	239	5	61	459	267	654	2e-80	274
rs:WP_014753667	DNA topoisomerase III [Pseudomonas putida].	37.44	422	245	8	36	454	240	645	2e-80	274
rs:WP_027252817	DNA topoisomerase III [Photobacterium halotolerans].	37.67	369	225	1	36	404	251	614	2e-80	274
rs:WP_007247388	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	38.92	424	246	5	31	452	236	648	2e-80	274
rs:WP_046832659	DNA topoisomerase III [Pseudomonas amygdali].	39.20	426	242	6	31	452	236	648	2e-80	274
rs:WP_020207115	DNA topoisomerase III [Cupriavidus sp. WS].	35.92	426	257	6	32	454	237	649	2e-80	274
rs:WP_048257658	DNA topoisomerase III [Pectobacterium carotovorum].	36.02	422	254	6	36	454	241	649	2e-80	274
rs:WP_047714007	DNA topoisomerase III [Pantoea ananatis].	37.47	419	246	7	36	450	242	648	2e-80	274
rs:WP_016402350	DNA topoisomerase III [Agarivorans albus].	37.22	403	244	3	36	437	251	645	2e-80	274
rs:WP_039136943	DNA topoisomerase III, partial [Gallibacterium genomosp. 2].	38.25	366	218	2	29	393	238	596	2e-80	272
rs:WP_039325610	DNA topoisomerase III [Pectobacterium betavasculorum].	36.84	399	241	4	61	459	267	654	2e-80	274
rs:WP_034079732	DNA topoisomerase III [Pseudomonas aeruginosa].	37.37	396	233	5	61	454	267	649	2e-80	274
rs:WP_005542694	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	38.75	369	219	2	36	404	259	620	2e-80	273
rs:WP_042870441	DNA topoisomerase III [Aeromonas piscicola].	38.29	410	235	6	36	436	249	649	2e-80	274
rs:WP_029569410	DNA topoisomerase III [Pantoea ananatis].	37.23	419	247	7	36	450	242	648	2e-80	274
rs:WP_015471954	Topoisomerase IA [Xanthomonas citri].	37.06	394	237	4	61	454	267	649	2e-80	274
rs:WP_012052641	MULTISPECIES: DNA topoisomerase III [Pseudomonas putida group].	37.18	425	251	8	36	459	240	649	2e-80	273
rs:WP_009521553	DNA topoisomerase III [Ralstonia sp. PBA].	37.12	423	249	8	36	454	241	650	2e-80	274
tr:D0KM86_PECWW	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	36.66	401	239	5	61	459	263	650	2e-80	274
rs:WP_044061218	DNA topoisomerase III [Pseudomonas aeruginosa].	35.61	424	262	5	32	454	237	650	2e-80	274
rs:WP_044177384	DNA topoisomerase III [Enterobacter massiliensis].	38.60	386	220	5	36	413	251	627	2e-80	273
rs:WP_043300054	DNA topoisomerase III [Burkholderia sp. TSV202].	35.60	427	265	4	29	454	234	651	2e-80	274
rs:WP_046481302	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	39.46	370	216	3	32	400	238	600	2e-80	272
rs:WP_013721848	DNA topoisomerase III [Alicycliphilus denitrificans].	36.08	424	260	7	32	454	237	650	2e-80	274
rs:WP_044314042	DNA topoisomerase III [Pseudomonas stutzeri].	37.63	396	232	6	61	454	267	649	2e-80	274
rs:WP_017409798	DNA topoisomerase III [Aeromonas hydrophila].	39.27	382	219	5	36	414	249	620	2e-80	273
tr:V8L219_XYLFS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	36.87	396	235	5	61	454	216	598	2e-80	273
rs:WP_014003991	DNA topoisomerase [Pseudomonas putida].	37.53	421	239	8	29	431	255	669	2e-80	277
rs:WP_011269736	DNA topoisomerase III [Xanthomonas campestris].	37.06	394	237	4	61	454	267	649	2e-80	274
rs:WP_045108681	DNA topoisomerase III [Moritella viscosa].	38.64	352	215	1	35	385	250	601	2e-80	273
rs:WP_027831559	DNA topoisomerase III [Marinobacter sp. HL-58].	34.25	473	262	5	29	459	247	712	2e-80	275
rs:WP_038275044	DNA topoisomerase III [Yersinia ruckeri].	37.47	395	234	4	57	449	262	645	2e-80	274
rs:WP_042063818	DNA topoisomerase III [Aeromonas allosaccharophila].	39.71	350	205	1	36	385	249	592	2e-80	274
rs:WP_046482944	DNA topoisomerase III [Pseudomonas veronii].	36.41	423	251	7	36	452	241	651	2e-80	274
rs:WP_039660485	DNA topoisomerase III, partial [Pantoea sp. MBLJ3].	41.14	350	198	3	36	385	149	490	2e-80	270
rs:WP_034017561	DNA topoisomerase III [Pseudomonas aeruginosa].	37.06	394	237	4	61	454	267	649	2e-80	274
rs:WP_039584862	DNA topoisomerase III [Xanthomonas axonopodis].	37.06	394	237	4	61	454	267	649	2e-80	274
rs:WP_001898889	DNA topoisomerase III, partial [Vibrio cholerae].	40.29	350	202	1	36	385	220	562	2e-80	272
rs:WP_018076215	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	36.88	423	250	8	36	454	241	650	2e-80	274
rs:WP_043988817	DNA topoisomerase III [Pectobacterium wasabiae].	36.66	401	239	5	61	459	267	654	2e-80	274
rs:WP_039551814	DNA topoisomerase III [Pectobacterium carotovorum].	36.66	401	239	5	61	459	267	654	2e-80	274
rs:WP_024650185	DNA topoisomerase III [Pseudomonas syringae].	38.92	424	246	5	31	452	236	648	2e-80	274
rs:WP_039212971	DNA topoisomerase III [Aeromonas hydrophila].	38.20	411	234	6	36	435	249	650	2e-80	273
rs:WP_048394718	DNA topoisomerase III [Pseudomonas lini].	38.77	374	226	2	36	408	241	612	3e-80	273
rs:WP_007946260	DNA topoisomerase III [Pseudomonas sp. GM21].	37.59	407	235	4	36	436	241	634	3e-80	273
rs:WP_038851309	DNA topoisomerase III [Pseudomonas fluorescens].	39.22	385	226	3	36	414	241	623	3e-80	273
rs:WP_015038895	DNA topoisomerase III [Bordetella parapertussis].	36.17	423	253	7	36	454	241	650	3e-80	273
rs:WP_033840334	DNA topoisomerase III [Bordetella bronchiseptica].	37.12	396	234	5	61	454	267	649	3e-80	273
rs:WP_032471176	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	3e-80	273
rs:WP_019751272	DNA topoisomerase III [Pseudomonas putida].	36.88	423	250	8	36	454	241	650	3e-80	273
rs:WP_047335925	DNA topoisomerase III [Pseudomonas fluorescens].	36.88	423	250	8	36	454	241	650	3e-80	273
rs:WP_023124756	MULTISPECIES: hypothetical protein [Pseudomonas].	37.06	394	237	4	61	454	267	649	3e-80	273
rs:WP_001764957	DNA topoisomerase III [Escherichia coli].	36.94	425	252	7	36	454	242	656	3e-80	274
rs:WP_041979771	DNA topoisomerase III [Xenorhabdus nematophila].	36.52	419	248	5	36	450	242	646	3e-80	273
rs:WP_032469697	DNA topoisomerase III, partial [Vibrio cholerae].	40.00	350	203	1	36	385	154	496	3e-80	270
rs:WP_015701195	DNA topoisomerase III [Pantoea ananatis].	38.19	419	243	8	36	450	242	648	3e-80	273
rs:WP_043554278	DNA topoisomerase III [Aeromonas bestiarum].	40.00	350	204	1	36	385	249	592	3e-80	273
tr:J2UTB3_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	37.10	407	237	4	36	436	245	638	3e-80	273
rs:WP_017244814	DNA topoisomerase III [Pseudomonas stutzeri].	36.88	423	250	8	36	454	241	650	3e-80	273
rs:WP_010675967	DNA topoisomerase III [Aeromonas caviae].	40.00	350	203	2	36	385	249	591	3e-80	273
rs:WP_003451175	DNA topoisomerase III in PFGI-1-like cluster [Pseudomonas pseudoalcaligenes].	36.88	423	250	8	36	454	241	650	3e-80	273
rs:WP_024942122	DNA topoisomerase III [Aeromonas hydrophila].	39.53	382	219	5	36	414	249	621	3e-80	273
rs:WP_048350967	DNA topoisomerase III [Pseudomonas psychrophila].	36.41	423	257	5	33	452	238	651	3e-80	273
rs:WP_016852000	DNA topoisomerase III [Pseudomonas aeruginosa].	36.88	423	250	8	36	454	241	650	3e-80	273
rs:WP_021206679	DNA topoisomerase III [Pseudomonas stutzeri].	38.72	390	230	3	23	408	229	613	3e-80	273
rs:WP_020846019	DNA topoisomerase III [Salmonella bongori].	39.43	383	224	3	29	409	232	608	3e-80	272
rs:WP_047783226	DNA topoisomerase III [Variovorax paradoxus].	37.63	396	232	5	61	454	267	649	3e-80	273
rs:WP_009601820	DNA topoisomerase III [Vibrio caribbeanicus].	40.06	357	208	1	36	392	255	605	3e-80	273
tr:A0A0A8NYT3_XENNE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	36.52	419	248	5	36	450	248	652	3e-80	273
rs:WP_043157988	DNA topoisomerase III [Pseudomonas aeruginosa].	36.88	423	250	8	36	454	241	650	3e-80	273
rs:WP_011805445	DNA topoisomerase III [Acidovorax sp. JS42].	36.88	423	250	8	36	454	241	650	3e-80	273
rs:WP_011866096	DNA topoisomerase III [Shewanella loihica].	39.83	354	212	1	32	385	247	599	3e-80	273
tr:U3U493_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	40.73	410	230	6	36	443	242	640	3e-80	274
rs:WP_009401127	DNA topoisomerase III [Pseudomonas putida].	35.85	424	261	7	32	454	237	650	3e-80	273
rs:WP_019829398	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	3e-80	273
rs:WP_006717380	DNA topoisomerase III [Aggregatibacter segnis].	38.65	370	220	2	35	404	258	620	4e-80	273
rs:WP_032472606	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	4e-80	273
rs:WP_004575589	DNA topoisomerase III [Pseudomonas putida].	36.53	427	252	8	36	459	240	650	4e-80	273
rs:WP_043154374	DNA topoisomerase III [Pseudomonas aeruginosa].	37.12	396	234	5	61	454	267	649	4e-80	273
rs:WP_032958220	DNA topoisomerase III [Bordetella hinzii].	36.08	424	260	7	32	454	237	650	4e-80	273
rs:WP_043741058	DNA topoisomerase III [Thauera sp. SWB20].	36.88	423	250	8	36	454	241	650	4e-80	273
rs:WP_012438475	DNA topoisomerase III [Xanthomonas campestris].	37.06	394	237	4	61	454	267	649	4e-80	273
rs:WP_029627393	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	4e-80	273
rs:WP_043221507	DNA topoisomerase III [Pseudomonas balearica].	36.88	423	250	8	36	454	241	650	4e-80	273
rs:WP_023912248	DNA topoisomerase III [Pseudomonas aeruginosa].	36.88	423	250	8	36	454	241	650	4e-80	273
rs:WP_028022843	DNA topoisomerase III [Enterovibrio calviensis].	39.57	369	216	3	36	404	251	612	4e-80	273
rs:WP_033036896	DNA topoisomerase III [Pseudomonas sp. GM102].	37.10	407	237	4	36	436	241	634	4e-80	273
rs:WP_043862902	DNA topoisomerase III [Pseudomonas putida].	35.38	424	262	5	32	454	237	649	4e-80	273
rs:WP_044593054	DNA topoisomerase III, partial [Salmonella enterica].	38.36	365	221	1	36	396	242	606	4e-80	271
rs:WP_039155132	DNA topoisomerase III [Gallibacterium anatis].	38.64	352	208	2	36	387	261	604	4e-80	273
rs:WP_017222480	DNA topoisomerase III [Moritella dasanensis].	38.35	352	216	1	35	385	250	601	4e-80	273
rs:WP_043142638	DNA topoisomerase III [Aeromonas salmonicida].	40.29	350	203	1	36	385	249	592	4e-80	273
rs:WP_041588598	DNA topoisomerase III, partial [Thalassolituus oleivorans].	39.27	354	214	1	32	385	249	601	4e-80	271
rs:WP_033482602	DNA topoisomerase III [Xanthomonas axonopodis].	37.06	394	237	4	61	454	267	649	4e-80	273
rs:WP_000197432	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	4e-80	272
rs:WP_016446175	DNA topoisomerase III [Delftia acidovorans].	36.88	423	250	8	36	454	241	650	4e-80	273
rs:WP_000197428	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	4e-80	272
rs:WP_017056476	DNA topoisomerase III [Vibrio kanaloae].	38.48	369	222	1	36	404	255	618	4e-80	273
rs:WP_046288283	DNA topoisomerase III [Pantoea sp. 3.5.1].	41.43	350	197	3	36	385	251	592	4e-80	272
rs:WP_041013332	DNA topoisomerase III [Pseudomonas xanthomarina].	36.88	423	250	8	36	454	241	650	5e-80	273
rs:WP_024677692	DNA topoisomerase III [Pseudomonas syringae].	39.15	424	245	5	31	452	236	648	5e-80	273
rs:WP_005705826	DNA topoisomerase III [Haemophilus parahaemolyticus].	40.00	350	202	2	36	385	252	593	5e-80	272
rs:WP_045700710	hypothetical protein, partial [Desulfobulbaceae bacterium BRH_c16a].	38.28	431	240	7	18	445	224	631	5e-80	272
rs:WP_016504282	DNA topoisomerase III, partial [Pasteurella multocida].	36.68	379	232	2	36	414	9	379	5e-80	265
rs:WP_047595520	DNA topoisomerase III [Pseudomonas plecoglossicida].	38.85	381	219	4	74	454	280	646	5e-80	273
rs:WP_033929799	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	5e-80	272
rs:WP_012639367	DNA topoisomerase III [Thioalkalivibrio sulfidiphilus].	36.67	420	255	5	36	454	241	650	5e-80	273
rs:WP_033959578	DNA topoisomerase III [Pseudomonas aeruginosa].	36.88	423	250	8	36	454	241	650	5e-80	273
rs:WP_004740668	DNA topoisomerase III [Vibrio splendidus].	38.48	369	222	1	36	404	255	618	5e-80	273
rs:WP_039503344	DNA topoisomerase III [Pectobacterium carotovorum].	36.41	401	240	5	61	459	267	654	5e-80	273
rs:WP_023657732	DNA topoisomerase III [Pseudomonas aeruginosa].	35.33	433	269	7	23	454	228	650	5e-80	273
rs:WP_036989946	DNA topoisomerase III [Pseudomonas bauzanensis].	37.84	399	238	5	61	459	267	655	5e-80	273
rs:WP_038984222	DNA topoisomerase III [Pseudomonas fluorescens].	38.77	374	226	2	36	408	241	612	5e-80	272
rs:WP_003487097	DNA topoisomerase III [Xanthomonas citri].	36.41	423	256	7	32	452	237	648	5e-80	273
rs:WP_042678050	DNA topoisomerase III [Pantoea sp. B40].	37.23	419	247	7	36	450	242	648	5e-80	273
rs:WP_027350505	DNA topoisomerase III [Halotalea alkalilenta].	37.00	427	252	8	32	454	237	650	5e-80	273
rs:WP_024914123	DNA topoisomerase III [Serratia multitudinisentens].	38.21	390	230	4	61	450	269	647	5e-80	273
rs:WP_042841609	DNA topoisomerase III [Xanthomonas euvesicatoria].	37.06	394	237	4	61	454	267	649	6e-80	273
rs:WP_046121448	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	6e-80	272
rs:WP_046553465	DNA topoisomerase III [Arsukibacterium sp. MJ3].	39.66	353	210	1	36	385	251	603	6e-80	273
rs:WP_009682480	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	37.05	421	241	8	29	431	254	668	6e-80	276
rs:WP_024420412	DNA topoisomerase III [Pseudomonas avellanae].	37.31	394	236	5	61	454	267	649	6e-80	273
rs:WP_047351009	DNA topoisomerase III [Diaphorobacter sp. J5-51].	35.38	424	263	6	32	454	237	650	6e-80	273
rs:WP_033732847	DNA topoisomerase III [Pantoea vagans].	41.60	351	195	4	36	385	251	592	6e-80	272
rs:WP_025889512	DNA topoisomerase III [Shewanella haliotis].	39.83	354	209	2	32	385	247	596	6e-80	273
tr:F3HNM9_PSEYM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	40.00	380	216	4	74	452	11	379	6e-80	265
rs:WP_042827100	DNA topoisomerase III [Xanthomonas axonopodis].	37.06	394	237	4	61	454	267	649	6e-80	273
rs:WP_011347486	DNA topoisomerase III [Xanthomonas euvesicatoria].	37.06	394	237	4	61	454	267	649	6e-80	273
rs:WP_002044380	DNA topoisomerase III [Vibrio cholerae].	38.22	382	227	2	36	417	255	627	6e-80	272
rs:WP_029996170	DNA topoisomerase III [Xanthomonas axonopodis].	37.06	394	237	4	61	454	267	649	6e-80	273
rs:WP_033131258	DNA topoisomerase III [Aeromonas aquatica].	40.57	350	201	1	36	385	249	591	6e-80	272
rs:WP_000197438	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	6e-80	272
rs:WP_041104383	DNA topoisomerase III [Pseudomonas stutzeri].	36.88	423	250	8	36	454	241	650	6e-80	273
rs:WP_046833637	DNA topoisomerase III [Xanthomonas axonopodis].	37.31	394	236	4	61	454	267	649	6e-80	273
rs:WP_009461166	MULTISPECIES: DNA topoisomerase III [Alcaligenes].	36.80	394	239	4	61	454	267	650	7e-80	273
rs:WP_005557593	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	38.48	369	220	2	36	404	259	620	7e-80	272
rs:WP_035416335	DNA topoisomerase III [Ferrimonas kyonanensis].	38.63	365	221	2	36	400	251	612	7e-80	272
rs:WP_014167642	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	38.48	369	220	2	36	404	259	620	7e-80	272
rs:WP_013519532	DNA topoisomerase III [Alicycliphilus denitrificans].	35.95	420	258	6	36	454	241	650	7e-80	273
rs:WP_044734317	DNA topoisomerase III [Shewanella algae].	38.10	378	230	2	32	409	247	620	7e-80	273
tr:A0A084IJ20_9GAMM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KEZ76704.1};	40.76	341	193	4	112	452	2	333	7e-80	263
rs:WP_014994483	MULTISPECIES: DNA topoisomerase III [Alcanivorax].	37.44	422	241	7	36	436	247	666	7e-80	273
rs:WP_033931233	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	7e-80	272
rs:WP_034104239	DNA topoisomerase III [Pseudomonas fluorescens].	38.46	377	223	3	36	408	241	612	7e-80	272
rs:WP_033986546	DNA topoisomerase III [Pseudomonas aeruginosa].	36.64	423	251	8	36	454	241	650	7e-80	272
rs:WP_034050572	DNA topoisomerase III [Pseudomonas aeruginosa].	36.88	423	250	8	36	454	241	650	7e-80	272
rs:WP_041216786	DNA topoisomerase III [Aeromonas hydrophila].	39.01	382	221	4	36	414	249	621	7e-80	272
rs:WP_000197431	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	7e-80	272
rs:WP_024718102	DNA topoisomerase III [Pseudomonas putida].	35.93	423	259	5	33	452	238	651	8e-80	272
rs:WP_034032947	DNA topoisomerase III [Pseudomonas aeruginosa].	37.82	394	230	5	61	452	267	647	8e-80	272
rs:WP_032477814	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	8e-80	272
rs:WP_032870234	DNA topoisomerase III [Pseudomonas fluorescens].	37.44	406	246	3	36	435	241	644	8e-80	272
rs:WP_043160134	DNA topoisomerase III [Aeromonas hydrophila].	39.01	382	221	4	36	414	249	621	8e-80	272
tr:L7HKF7_PSEFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	37.44	406	246	3	36	435	243	646	8e-80	272
rs:WP_038625712	DNA topoisomerase III [Pantoea sp. PSNIH2].	35.83	427	257	7	32	454	237	650	8e-80	272
rs:WP_006990687	DNA topoisomerase III [Paraglaciecola mesophila].	41.06	341	192	1	36	376	254	585	8e-80	271
rs:WP_000197427	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	8e-80	271
rs:WP_027925328	DNA topoisomerase III [Pseudomonas sp. URMO17WK12:I12].	40.11	359	208	2	61	414	267	623	9e-80	271
tr:M5DMV3_9GAMM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	39.27	354	214	1	32	385	249	601	9e-80	272
rs:WP_004265528	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	35.83	427	257	7	32	454	237	650	9e-80	272
tr:X2JT78_AGGAC	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.48	369	220	2	36	404	274	635	9e-80	272
rs:WP_016849630	DNA topoisomerase III [Xanthomonas axonopodis].	37.06	394	237	4	61	454	267	649	1e-79	272
rs:WP_003289344	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	36.36	429	256	6	35	459	240	655	1e-79	272
rs:WP_034021230	DNA topoisomerase III [Pseudomonas aeruginosa].	37.35	431	259	5	25	454	230	650	1e-79	272
rs:WP_029302276	DNA topoisomerase III [Aeromonas hydrophila].	37.96	411	235	7	36	435	249	650	1e-79	271
rs:WP_019935838	DNA topoisomerase III [Oceanimonas smirnovii].	39.32	351	210	1	35	385	250	597	1e-79	271
rs:WP_033470610	DNA topoisomerase III [Bordetella bronchiseptica].	37.14	420	253	5	36	454	241	650	1e-79	272
rs:WP_033991652	DNA topoisomerase III [Pseudomonas aeruginosa].	36.80	394	238	4	61	454	267	649	1e-79	272
rs:WP_046940204	hypothetical protein, partial [Xanthomonas euvesicatoria].	35.82	469	250	11	32	454	110	573	1e-79	270
rs:WP_044801014	DNA topoisomerase III [Aeromonas hydrophila].	39.27	382	220	5	36	414	249	621	1e-79	271
rs:WP_042005726	DNA topoisomerase III [Aeromonas dhakensis].	39.89	371	212	4	36	403	249	611	1e-79	271
rs:WP_019335150	DNA topoisomerase III [Pseudomonas syringae].	38.92	424	246	5	31	452	236	648	1e-79	272
rs:WP_029133587	DNA topoisomerase III [Sedimenticola selenatireducens].	36.41	423	252	8	36	454	241	650	1e-79	272
rs:WP_033448876	MULTISPECIES: DNA topoisomerase III [Alcaligenaceae].	37.69	390	228	5	67	454	273	649	1e-79	272
rs:WP_039431367	DNA topoisomerase III [Xanthomonas vasicola].	37.06	394	237	5	61	454	267	649	1e-79	272
rs:WP_021615661	DNA topoisomerase [Aggregatibacter sp. oral taxon 458].	40.74	351	199	4	36	385	259	601	1e-79	271
rs:WP_033902057	DNA topoisomerase III [Pseudomonas sp. FH1].	38.70	385	228	3	36	414	241	623	1e-79	271
rs:WP_025264565	DNA topoisomerase III [Thalassolituus oleivorans].	39.27	354	214	1	32	385	249	601	1e-79	272
tr:A0A0E9ZTW1_9PSED	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KIY42324.1};	38.66	388	224	4	67	454	272	645	1e-79	271
rs:WP_029686830	DNA topoisomerase III [Tatumella saanichensis].	39.44	355	197	4	36	385	251	592	1e-79	271
rs:WP_043132818	DNA topoisomerase III [Aeromonas media].	38.48	408	238	5	36	438	249	648	1e-79	271
rs:WP_040976203	DNA topoisomerase III [Pasteurella sp. FF6].	38.75	369	219	2	36	404	253	614	1e-79	271
rs:WP_029304903	DNA topoisomerase III [Aeromonas hydrophila].	38.20	411	234	7	36	435	249	650	1e-79	271
rs:WP_032475343	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	1e-79	271
rs:WP_043165453	DNA topoisomerase III [Aeromonas hydrophila].	39.35	371	214	3	36	403	249	611	1e-79	271
rs:WP_014421986	DNA topoisomerase III [Marinobacter hydrocarbonoclasticus].	36.58	473	250	5	30	459	248	713	1e-79	273
rs:WP_039086821	DNA topoisomerase III [Gallibacterium anatis].	38.31	355	211	2	36	390	261	607	1e-79	271
rs:WP_000197437	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	1e-79	271
rs:WP_040239258	DNA topoisomerase III [Xanthomonas citri].	37.06	394	237	4	61	454	267	649	1e-79	271
rs:WP_019615207	DNA topoisomerase III [Psychromonas ossibalaenae].	37.40	377	219	3	36	412	254	613	1e-79	271
rs:WP_028622299	DNA topoisomerase III [Pseudomonas sp. Ant30-3].	35.70	423	260	5	33	452	238	651	1e-79	272
rs:WP_033836471	DNA topoisomerase III [Xanthomonas citri].	37.31	394	236	5	61	454	267	649	1e-79	271
rs:WP_039338988	DNA topoisomerase III [Pantoea stewartii].	37.77	421	242	9	36	450	242	648	1e-79	271
rs:WP_017012778	DNA topoisomerase III [Enterovibrio calviensis].	39.57	369	216	3	36	404	251	612	1e-79	271
rs:WP_023122311	hypothetical protein [Pseudomonas aeruginosa].	37.08	418	252	6	36	452	241	648	1e-79	271
rs:WP_025389726	DNA topoisomerase III [Pseudomonas syringae].	36.87	396	235	5	61	454	267	649	2e-79	271
rs:WP_038020819	DNA topoisomerase III [Tatumella morbirosei].	40.29	350	201	3	36	385	251	592	2e-79	271
rs:WP_013509359	DNA topoisomerase III [Pantoea sp. At-9b].	40.57	350	200	3	36	385	251	592	2e-79	271
rs:WP_013085583	conjugal transfer protein TraE [Neisseria gonorrhoeae].	32.39	494	281	3	19	459	229	722	2e-79	273
rs:WP_005567881	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	38.48	369	220	2	36	404	259	620	2e-79	271
rs:WP_039587992	DNA topoisomerase III [Xanthomonas axonopodis].	37.06	394	237	4	61	454	267	649	2e-79	271
rs:WP_011347592	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	36.87	396	235	5	61	454	267	649	2e-79	271
rs:WP_002053203	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	2e-79	271
rs:WP_041025084	DNA topoisomerase III [Pseudomonas aeruginosa].	37.12	396	234	5	61	454	267	649	2e-79	271
rs:WP_041209572	DNA topoisomerase III [Aeromonas jandaei].	39.58	379	221	2	36	412	249	621	2e-79	271
rs:WP_042650606	DNA topoisomerase III [Aeromonas media].	37.92	414	236	5	36	436	249	654	2e-79	271
rs:WP_008151456	DNA topoisomerase III [Pseudomonas sp. GM41(2012)].	38.32	381	217	3	61	436	267	634	2e-79	271
rs:WP_016977365	DNA topoisomerase III [Pseudomonas fluorescens].	37.68	406	245	3	36	435	241	644	2e-79	271
rs:WP_033472286	DNA topoisomerase III [Bordetella bronchiseptica].	37.69	390	228	5	67	454	273	649	2e-79	271
rs:WP_019098998	DNA topoisomerase III [Pseudomonas putida].	36.97	422	247	8	36	454	240	645	2e-79	271
rs:WP_000197441	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	2e-79	271
rs:WP_033981900	DNA topoisomerase III [Pseudomonas aeruginosa].	37.12	396	234	5	61	454	267	649	2e-79	271
tr:W4RYY9_9XANT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	35.53	425	263	5	32	454	193	608	2e-79	270
rs:WP_042988236	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	2e-79	271
rs:WP_001959922	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	2e-79	271
rs:WP_041510970	DNA topoisomerase III [Shewanella sp. cp20].	39.55	354	213	1	32	385	247	599	2e-79	272
rs:WP_023082340	hypothetical protein [Pseudomonas aeruginosa].	36.87	396	235	5	61	454	267	649	2e-79	271
rs:WP_040244399	DNA topoisomerase III [Xanthomonas citri].	36.99	392	236	4	61	452	267	647	2e-79	271
rs:WP_041048795	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	2e-79	271
rs:WP_042920648	DNA topoisomerase III [Pseudomonas chloritidismutans].	36.62	396	236	5	61	454	267	649	2e-79	271
rs:WP_032473562	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	2e-79	271
rs:WP_046048951	DNA topoisomerase III [Pseudomonas fluorescens].	38.32	381	217	3	61	436	267	634	2e-79	271
tr:J3IDL5_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	38.32	381	217	3	61	436	271	638	2e-79	271
rs:WP_008925300	DNA topoisomerase III [Pantoea sp. aB].	41.14	350	198	3	36	385	251	592	2e-79	270
rs:WP_030130788	DNA topoisomerase III [Pseudomonas sp. QTF5].	38.32	381	217	3	61	436	267	634	2e-79	271
rs:WP_033932793	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	2e-79	271
rs:WP_032830402	DNA topoisomerase III [Pseudomonas sp. GM79].	38.32	381	217	3	61	436	267	634	2e-79	271
rs:WP_047884019	DNA topoisomerase III [Photobacterium ganghwense].	38.48	369	225	2	36	404	251	617	2e-79	271
rs:WP_036023794	DNA topoisomerase III [Leminorella grimontii].	39.30	369	216	3	32	400	247	607	2e-79	271
rs:WP_044393699	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	39.15	424	245	5	31	452	236	648	2e-79	271
rs:WP_000197433	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	2e-79	271
rs:WP_033928704	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	2e-79	271
rs:WP_023093157	hypothetical protein [Pseudomonas aeruginosa].	35.85	424	261	7	32	454	237	650	2e-79	271
rs:WP_047925746	DNA topoisomerase III [Pseudomonas aeruginosa].	34.63	436	268	6	23	454	228	650	2e-79	271
rs:WP_043953786	DNA topoisomerase III [Enterobacter sp. YD4].	37.31	402	243	4	36	437	251	643	2e-79	271
rs:WP_013982117	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	34.63	436	268	6	23	454	228	650	2e-79	271
rs:WP_030132226	DNA topoisomerase III [Pseudomonas sp. QTF5].	34.51	426	263	6	32	454	237	649	2e-79	271
rs:WP_008374266	DNA topoisomerase III [Pseudomonas sp. M47T1].	38.72	390	225	5	65	454	271	646	2e-79	271
rs:WP_045832167	DNA topoisomerase III [Pantoea sp. BL1].	40.57	350	200	3	36	385	251	592	2e-79	270
rs:WP_039168663	DNA topoisomerase III [Gallibacterium anatis].	38.64	352	208	2	36	387	261	604	2e-79	270
rs:WP_006410664	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	37.00	427	252	8	32	454	237	650	2e-79	271
rs:WP_048234004	DNA topoisomerase III [Citrobacter freundii].	39.36	376	220	3	29	402	232	601	2e-79	269
rs:WP_046037339	DNA topoisomerase III [Pseudomonas fluorescens].	39.66	358	210	2	61	414	270	625	2e-79	270
rs:WP_000197436	DNA topoisomerase III [Vibrio cholerae].	40.00	350	203	1	36	385	255	597	2e-79	270
rs:WP_005577855	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	38.48	369	220	2	36	404	259	620	2e-79	270
rs:WP_028781076	DNA topoisomerase III [Shewanella sp. 38A_GOM-205m].	39.55	354	210	2	32	385	247	596	3e-79	271
rs:WP_012701283	DNA topoisomerase III [Azotobacter vinelandii].	37.56	394	241	3	23	415	231	620	3e-79	270
rs:WP_041406328	DNA topoisomerase III, partial [Shewanella denitrificans].	38.14	354	215	1	36	385	251	604	3e-79	270
rs:WP_021022293	DNA topoisomerase III [Salinivibrio costicola].	40.86	350	199	2	36	385	251	592	3e-79	270
rs:WP_028940230	DNA topoisomerase III [Pseudomonas umsongensis].	38.32	381	217	3	61	436	267	634	3e-79	270
rs:WP_042072495	DNA topoisomerase III [Aeromonas enteropelogenes].	40.29	350	203	1	36	385	249	592	3e-79	271
rs:WP_008367437	DNA topoisomerase III [Pseudomonas sp. M47T1].	38.77	374	226	2	36	408	241	612	3e-79	270
rs:WP_024889628	DNA topoisomerase III [Luteimonas huabeiensis].	36.41	423	252	8	36	454	241	650	3e-79	271
rs:WP_033947985	DNA topoisomerase III [Pseudomonas aeruginosa].	36.62	396	236	5	61	454	267	649	3e-79	271
rs:WP_039095869	DNA topoisomerase III [Gallibacterium anatis].	38.35	352	209	2	36	387	261	604	3e-79	270
rs:WP_024767679	DNA topoisomerase III [Pseudomonas nitroreducens].	37.06	394	238	4	61	454	267	650	3e-79	271
rs:WP_034119183	DNA topoisomerase III [Pseudomonas fluorescens].	38.44	385	229	3	36	414	241	623	3e-79	270
rs:WP_023112340	MULTISPECIES: hypothetical protein [Pseudomonas].	35.55	422	256	6	36	454	241	649	3e-79	271
rs:WP_024537139	DNA topoisomerase III [Comamonas badia].	35.61	424	262	7	32	454	237	650	3e-79	271
rs:WP_023098636	hypothetical protein [Pseudomonas aeruginosa].	36.89	431	261	5	25	454	230	650	3e-79	271
rs:WP_040095505	DNA topoisomerase III [Aeromonas australiensis].	38.26	379	226	2	36	412	249	621	3e-79	270
rs:WP_048389285	DNA topoisomerase III [Pseudomonas sp. DSM 28141].	36.17	423	258	5	33	452	238	651	3e-79	271
rs:WP_005332660	DNA topoisomerase III [Aeromonas media].	38.24	408	239	5	36	438	249	648	3e-79	270
rs:WP_000197440	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	3e-79	270
tr:Q12LJ6_SHEDO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.14	354	215	1	36	385	251	604	3e-79	271
rs:WP_028622141	DNA topoisomerase III [Pseudomonas sp. Ant30-3].	38.32	381	217	3	61	436	267	634	3e-79	270
rs:WP_033910164	conjugal transfer protein TraE [Neisseria gonorrhoeae].	32.39	494	281	3	19	459	229	722	3e-79	272
rs:WP_036566114	DNA topoisomerase III [Oceanospirillum beijerinckii].	36.87	377	227	2	35	411	254	619	3e-79	270
rs:WP_017339501	DNA topoisomerase III [Pseudomonas fluorescens].	38.06	381	218	3	61	436	267	634	3e-79	270
rs:WP_026136771	DNA topoisomerase III [Pseudomonas sp. CBZ-4].	37.97	403	245	3	36	435	241	641	3e-79	270
rs:WP_038179981	DNA topoisomerase III [Vibrio rhizosphaerae].	41.60	351	197	3	36	386	257	599	3e-79	270
rs:WP_003852758	DNA topoisomerase III [Pantoea agglomerans].	41.14	350	198	3	36	385	251	592	3e-79	270
rs:WP_032942259	DNA topoisomerase III [Citrobacter freundii].	39.10	376	221	3	29	402	232	601	3e-79	269
rs:WP_039081471	DNA topoisomerase III [Gallibacterium anatis].	38.64	352	208	2	36	387	261	604	3e-79	270
rs:WP_034032722	DNA topoisomerase III [Pseudomonas aeruginosa].	36.99	392	236	4	61	452	267	647	3e-79	271
rs:WP_013358056	DNA topoisomerase III [Pantoea vagans].	41.31	351	196	4	36	385	251	592	3e-79	270
rs:WP_016488133	DNA topoisomerase III [Pseudomonas putida].	39.20	375	223	3	36	408	241	612	3e-79	270
rs:WP_017799846	DNA topoisomerase III [Erwinia toletana].	41.14	350	198	3	36	385	251	592	3e-79	270
rs:WP_034828805	DNA topoisomerase III [Enterobacter cancerogenus].	40.57	350	200	3	36	385	251	592	3e-79	270
rs:WP_033474391	DNA topoisomerase III [Bordetella bronchiseptica].	36.87	396	235	5	61	454	267	649	3e-79	271
rs:WP_022992872	DNA topoisomerase III [Marinobacter sp. C1S70].	36.36	473	251	5	30	459	248	713	4e-79	272
rs:WP_033874957	DNA topoisomerase III [Pseudomonas aeruginosa].	36.41	423	252	8	36	454	241	650	4e-79	271
rs:WP_034031049	DNA topoisomerase III [Pseudomonas aeruginosa].	36.17	423	253	8	36	454	241	650	4e-79	270
rs:WP_006032728	DNA topoisomerase III [Moritella sp. PE36].	35.48	403	251	2	35	436	250	644	4e-79	270
rs:WP_015697218	DNA topoisomerase III [Rahnella aquatilis].	38.71	372	220	3	36	407	251	614	4e-79	270
rs:WP_033054459	DNA topoisomerase III [Pseudomonas mandelii].	38.32	381	217	3	61	436	267	634	4e-79	270
rs:WP_043104890	DNA topoisomerase III [Pseudomonas aeruginosa].	36.64	423	251	8	36	454	241	650	4e-79	270
rs:WP_033783268	DNA topoisomerase III [Pantoea sp. 9140].	41.31	351	196	4	36	385	251	592	4e-79	270
rs:WP_045816089	DNA topoisomerase III [Pantoea sp. SM3].	40.57	350	200	3	36	385	251	592	4e-79	270
rs:WP_046056719	DNA topoisomerase III [Pseudomonas fluorescens].	38.32	381	217	3	61	436	267	634	4e-79	270
rs:WP_023464545	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	36.45	417	254	5	39	454	244	650	4e-79	270
rs:WP_034617905	DNA topoisomerase III [Chelonobacter oris].	37.74	371	223	2	36	406	253	615	4e-79	270
rs:WP_019579443	DNA topoisomerase III [Pseudomonas mandelii].	38.32	381	217	3	61	436	267	634	4e-79	270
tr:J2T5I3_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	38.85	381	215	4	61	436	271	638	4e-79	270
rs:WP_013185062	DNA topoisomerase III [Xenorhabdus nematophila].	35.28	445	262	6	18	450	213	643	4e-79	270
rs:WP_003141052	DNA topoisomerase III [Pseudomonas aeruginosa].	36.17	423	253	8	36	454	241	650	4e-79	270
rs:WP_011468024	DNA topoisomerase III [Saccharophagus degradans].	37.02	362	224	1	35	392	252	613	4e-79	270
rs:WP_023085000	hypothetical protein [Pseudomonas aeruginosa].	36.17	423	253	8	36	454	241	650	4e-79	270
rs:WP_035886129	DNA topoisomerase III [Kosakonia radicincitans].	37.31	402	243	4	36	437	251	643	4e-79	270
rs:WP_028724189	DNA topoisomerase III [Pantoea ananatis].	36.99	419	248	7	36	450	242	648	4e-79	270
rs:WP_043743360	DNA topoisomerase III [Thauera sp. SWB20].	35.61	424	262	7	32	454	237	650	4e-79	270
rs:WP_021461897	DNA topoisomerase III [Gallibacterium anatis].	38.31	355	211	2	36	390	261	607	4e-79	270
rs:WP_023011009	DNA topoisomerase III [Marinobacter sp. EN3].	36.11	504	265	8	3	459	220	713	4e-79	271
rs:WP_013185129	DNA topoisomerase III [Xenorhabdus nematophila].	35.37	441	259	6	22	450	217	643	5e-79	270
rs:WP_033990355	DNA topoisomerase III [Pseudomonas aeruginosa].	36.64	423	251	8	36	454	241	650	5e-79	270
rs:WP_007374606	DNA topoisomerase III [Kosakonia radicincitans].	37.31	402	243	4	36	437	251	643	5e-79	270
rs:WP_032834930	DNA topoisomerase III [Pseudomonas sp. GM50].	38.85	381	215	4	61	436	267	634	5e-79	270
gp:CP008992_2210	DNA topoisomerase III, bacteria and conjugative plasmid [Xanthomonas citri subsp. citri UI6]	35.35	430	255	7	36	454	134	551	5e-79	268
rs:WP_009654423	DNA topoisomerase III [Klebsiella sp. OBRC7].	40.77	363	207	3	29	389	232	588	5e-79	269
rs:WP_007971786	DNA topoisomerase III [Pseudomonas sp. GM33].	38.28	384	230	3	36	414	244	625	5e-79	270
rs:WP_008733910	DNA topoisomerase III [Alcanivorax pacificus].	36.43	420	256	5	36	454	241	650	5e-79	270
rs:WP_031590979	DNA topoisomerase III [Klebsiella pneumoniae].	40.50	363	208	3	29	389	232	588	5e-79	268
tr:W4SCH7_9XANT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	35.53	425	263	5	32	454	237	652	5e-79	270
rs:WP_035246216	hypothetical protein, partial [Desulfobulbus mediterraneus].	38.94	416	224	9	34	444	241	631	6e-79	269
rs:WP_039384680	DNA topoisomerase III [Pantoea sp. PSNIH1].	40.29	350	201	3	36	385	251	592	6e-79	269
rs:WP_038646639	DNA topoisomerase III [Pantoea rwandensis].	40.57	350	200	3	36	385	251	592	6e-79	269
rs:WP_032903512	DNA topoisomerase III [Pseudomonas fluorescens].	38.24	374	228	2	36	408	241	612	6e-79	270
rs:WP_040216197	DNA topoisomerase III [Haemophilus parahaemolyticus].	39.43	350	204	2	36	385	252	593	6e-79	269
rs:WP_033986198	DNA topoisomerase III [Pseudomonas aeruginosa].	36.41	423	252	8	36	454	241	650	6e-79	270
rs:WP_010459568	DNA topoisomerase III [Pseudomonas mandelii].	38.32	381	217	3	61	436	267	634	6e-79	270
rs:WP_014159680	DNA topoisomerase III [Pseudoxanthomonas spadix].	36.10	421	251	8	36	452	241	647	6e-79	270
rs:WP_018988644	DNA topoisomerase III [Azoarcus toluclasticus].	35.53	425	261	7	32	454	237	650	6e-79	270
rs:WP_046019227	DNA topoisomerase III [Marinomonas sp. S3726].	36.83	372	228	2	35	406	250	614	6e-79	269
rs:WP_047366551	DNA topoisomerase III [Enterobacter sp. GN02226].	39.18	388	221	4	29	414	232	606	6e-79	268
rs:WP_008303213	DNA topoisomerase III [Paraglaciecola agarilytica].	40.00	350	201	1	36	385	254	594	6e-79	269
rs:WP_027849899	DNA topoisomerase III [Marinospirillum insulare].	37.85	354	217	1	32	385	247	597	7e-79	269
rs:WP_005546712	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	38.21	369	221	2	36	404	259	620	7e-79	269
rs:WP_032670646	DNA topoisomerase III [Enterobacter cloacae].	39.43	383	224	3	29	409	232	608	7e-79	268
rs:WP_032480933	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	7e-79	269
rs:WP_011785988	DNA topoisomerase III [Marinobacter hydrocarbonoclasticus].	36.36	473	251	5	30	459	248	713	7e-79	271
rs:WP_009089894	DNA topoisomerase III [Pantoea sp. Sc1].	40.57	350	200	3	36	385	251	592	7e-79	269
rs:WP_047608385	DNA topoisomerase III [Rahnella aquatilis].	38.71	372	220	3	36	407	251	614	7e-79	269
rs:WP_039137280	DNA topoisomerase III [Gallibacterium genomosp. 2].	38.03	355	212	2	36	390	261	607	7e-79	269
rs:WP_024483847	DNA topoisomerase III [Serratia fonticola].	37.22	395	235	5	57	449	262	645	7e-79	270
rs:WP_000197429	DNA topoisomerase III [Vibrio cholerae].	40.00	350	203	1	36	385	255	597	7e-79	269
rs:WP_027847842	DNA topoisomerase III [Marinospirillum minutulum].	38.42	354	215	1	32	385	247	597	7e-79	269
rs:WP_032905030	DNA topoisomerase III [Pseudomonas sp. CF150].	38.24	374	228	2	36	408	241	612	7e-79	269
rs:WP_042064235	DNA topoisomerase III [Aeromonas hydrophila].	39.35	371	214	4	36	403	249	611	7e-79	270
rs:WP_046126935	DNA topoisomerase III [Vibrio cholerae].	40.29	350	202	1	36	385	255	597	7e-79	269
rs:WP_039159053	DNA topoisomerase III [Gallibacterium anatis].	38.64	352	208	2	36	387	261	604	7e-79	269
rs:WP_039161879	DNA topoisomerase III [Gallibacterium anatis].	38.35	352	209	2	36	387	261	604	8e-79	269
rs:WP_003604286	DNA topoisomerase III [Methylobacterium extorquens].	41.45	386	212	8	31	408	249	628	8e-79	274
rs:WP_034365963	DNA topoisomerase III [Delftia sp. 670].	35.85	424	261	7	32	454	237	650	8e-79	270
rs:WP_039459217	DNA topoisomerase III [Photobacterium gaetbulicola].	38.75	369	222	2	36	404	251	615	8e-79	269
rs:WP_020192167	DNA topoisomerase III [Pseudomonas putida].	35.61	424	262	7	32	454	237	650	8e-79	270
rs:WP_024025285	DNA topoisomerase III [Marinomonas profundimaris].	37.11	388	236	4	32	417	247	628	8e-79	270
rs:WP_033186461	DNA topoisomerase III [Pseudoalteromonas sp. PLSV].	40.00	350	201	1	36	385	254	594	8e-79	269
rs:WP_026345770	DNA topoisomerase III [Pseudomonas sp. 45MFCol3.1].	38.32	381	217	3	61	436	267	634	8e-79	269
rs:WP_033955548	DNA topoisomerase III [Pseudomonas aeruginosa].	36.64	423	251	8	36	454	241	650	8e-79	270
tr:A0A080KI01_9GAMM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.04	351	220	1	36	385	257	607	8e-79	268
rs:WP_038059221	hypothetical protein, partial [Thiobacillus denitrificans].	35.93	462	270	11	16	459	194	647	8e-79	269
rs:WP_016192491	DNA topoisomerase III [Erwinia tracheiphila].	41.14	350	198	3	36	385	251	592	9e-79	269
rs:WP_043293257	DNA topoisomerase III [Pseudomonas sp. LAMO17WK12:I2].	38.44	385	229	3	36	414	241	623	9e-79	269
rs:WP_039084901	DNA topoisomerase III [Gallibacterium anatis].	38.03	355	212	2	36	390	261	607	9e-79	269
rs:WP_024781366	DNA topoisomerase III [Pseudomonas corrugata].	37.47	387	237	3	31	414	236	620	9e-79	269
rs:WP_039386234	DNA topoisomerase III [Pantoea agglomerans].	40.57	350	200	3	36	385	251	592	9e-79	269
rs:WP_012754023	DNA topoisomerase III [Methylobacterium extorquens].	41.45	386	212	8	31	408	249	628	9e-79	274
rs:WP_041851653	DNA topoisomerase III [Enterobacter sp. Bisph2].	37.16	401	237	6	36	434	251	638	9e-79	269
rs:WP_005701059	DNA topoisomerase III [Aggregatibacter aphrophilus].	38.65	370	218	4	36	404	253	614	9e-79	268
rs:WP_044622876	DNA topoisomerase III [Photobacterium gaetbulicola].	39.78	357	211	2	36	392	251	603	9e-79	269
rs:WP_013752942	DNA topoisomerase III [Glaciecola sp. 4H-3-7+YE-5].	40.00	350	201	1	36	385	254	594	9e-79	269
rs:WP_044127250	DNA topoisomerase III [Vibrio cholerae].	40.00	350	203	1	36	385	255	597	1e-78	269
rs:WP_037033921	DNA topoisomerase III [Rahnella sp. WP5].	38.44	372	221	3	36	407	251	614	1e-78	269
rs:WP_047682544	DNA topoisomerase III [Xenorhabdus sp. NBAII XenSa04].	39.83	354	197	4	36	385	251	592	1e-78	269
rs:WP_045102431	DNA topoisomerase III [Aliivibrio wodanis].	37.60	383	232	3	22	404	248	623	1e-78	269
rs:WP_022622166	DNA topoisomerase III [Pantoea ananatis].	36.75	419	249	7	36	450	242	648	1e-78	269
rs:WP_034456056	DNA topoisomerase III [Buttiauxella agrestis].	37.99	379	227	3	36	414	251	621	1e-78	269
rs:WP_003211612	DNA topoisomerase III [Pseudomonas fluorescens].	36.61	407	239	4	36	436	241	634	1e-78	269
rs:WP_032479936	DNA topoisomerase III [Vibrio cholerae].	40.00	350	203	1	36	385	255	597	1e-78	269
rs:WP_034280392	conjugal transfer protein TraE, partial [Alkanindiges illinoisensis].	35.00	480	256	6	35	459	244	722	1e-78	270
rs:WP_047369938	DNA topoisomerase III [Kluyvera intermedia].	40.46	351	199	4	36	385	251	592	1e-78	269
rs:WP_000197442	DNA topoisomerase III [Vibrio cholerae].	40.00	350	203	1	36	385	255	597	1e-78	269
rs:WP_013575369	MULTISPECIES: DNA topoisomerase III [Rahnella].	38.44	372	221	3	36	407	251	614	1e-78	269
rs:WP_032718932	DNA topoisomerase III [Klebsiella oxytoca].	40.77	363	207	3	29	389	232	588	1e-78	268
rs:WP_019690070	DNA topoisomerase III [Pseudomonas fluorescens].	37.40	385	233	3	36	414	241	623	1e-78	269
rs:WP_034882663	DNA topoisomerase III, partial [Gilliamella apicola].	37.04	351	220	1	36	385	257	607	1e-78	268
rs:WP_047526635	DNA topoisomerase III [Pseudomonas sp. 11/12A].	35.60	427	258	8	32	454	237	650	1e-78	269
rs:WP_027907079	DNA topoisomerase III [Pseudomonas taiwanensis].	37.44	406	246	4	36	436	241	643	1e-78	268
rs:WP_046072708	DNA topoisomerase III [Pseudomonas fluorescens].	37.97	374	229	2	36	408	241	612	1e-78	268
rs:WP_012325583	DNA topoisomerase III [Shewanella woodyi].	38.80	366	210	2	32	386	247	609	1e-78	269
rs:WP_018692714	hypothetical protein [Algicola sagamiensis].	37.02	389	240	1	32	420	247	630	1e-78	268
rs:WP_006011047	DNA topoisomerase III [Glaciecola pallidula].	37.57	378	227	2	36	413	251	619	1e-78	268
rs:WP_019105610	DNA topoisomerase III [Pantoea ananatis].	36.75	419	249	7	36	450	242	648	1e-78	269
rs:WP_047712129	DNA topoisomerase III [Pseudomonas fluorescens].	37.92	385	231	3	36	414	241	623	2e-78	268
rs:WP_033064134	DNA topoisomerase III [Pseudomonas sp. GM18].	38.32	381	217	3	61	436	267	634	2e-78	268
rs:WP_034018007	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	35.81	444	259	7	31	459	51	483	2e-78	266
rs:WP_045156433	DNA topoisomerase III [Pseudomonas fluorescens].	37.14	412	240	4	31	436	236	634	2e-78	268
rs:WP_042036004	DNA topoisomerase III [Aeromonas popoffii].	40.86	350	200	2	36	385	249	591	2e-78	268
rs:WP_040069566	DNA topoisomerase III [Pseudomonas batumici].	38.68	380	226	2	60	434	266	643	2e-78	268
rs:WP_023381104	DNA topoisomerase III [Pseudomonas sp. VLB120].	39.06	384	226	4	36	414	241	621	2e-78	268
rs:WP_006661664	DNA topoisomerase III [Providencia alcalifaciens].	39.32	351	210	1	35	385	250	597	2e-78	268
tr:J2NSS9_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	38.32	381	217	3	61	436	270	637	2e-78	268
rs:WP_017004793	DNA topoisomerase III [Enterovibrio norvegicus].	39.57	369	216	3	36	404	251	612	2e-78	268
rs:WP_032734403	DNA topoisomerase III [Klebsiella oxytoca].	41.05	363	206	3	29	389	232	588	2e-78	267
tr:A0A080LLZ6_9GAMM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	36.56	372	235	1	36	406	257	628	2e-78	268
rs:WP_045973488	DNA topoisomerase III [Xenorhabdus doucetiae].	40.17	361	199	5	36	391	251	599	2e-78	268
rs:WP_013792850	DNA topoisomerase III [Pseudomonas fulva].	37.21	387	240	2	23	408	228	612	2e-78	268
rs:WP_019342298	DNA topoisomerase III [Pseudomonas stutzeri].	37.15	428	248	5	23	437	228	647	2e-78	268
rs:WP_039589247	DNA topoisomerase III [Pseudomonas frederiksbergensis].	37.14	412	240	4	31	436	236	634	2e-78	268
rs:WP_008537480	DNA topoisomerase III [Megamonas funiformis].	32.61	463	253	6	41	458	250	698	2e-78	270
rs:WP_047875730	DNA topoisomerase III [Photobacterium aphoticum].	38.65	370	221	2	36	404	251	615	2e-78	269
rs:WP_017456522	DNA topoisomerase III [Kosakonia sacchari].	37.31	402	243	4	36	437	251	643	2e-78	268
rs:WP_020308035	DNA topoisomerase III [Pseudomonas stutzeri].	35.61	424	262	7	32	454	237	650	2e-78	268
rs:WP_025903047	MULTISPECIES: DNA topoisomerase III [Tatumella].	40.00	350	202	3	36	385	251	592	2e-78	268
rs:WP_008813734	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	40.29	350	201	3	36	385	251	592	2e-78	268
rs:WP_021264249	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	36.62	396	236	5	61	454	267	649	2e-78	268
rs:WP_011262202	DNA topoisomerase III [Aliivibrio fischeri].	37.08	391	239	3	14	404	249	632	2e-78	268
rs:WP_015336640	DNA topoisomerase type IA central domain protein [Desulfovibrio hydrothermalis].	33.75	483	255	6	35	459	243	718	2e-78	270
rs:WP_020680308	DNA topoisomerase III [Marinobacterium rhizophilum].	36.68	398	245	2	36	432	251	642	2e-78	268
rs:WP_038612001	DNA topoisomerase III [Pseudomonas alkylphenolia].	35.95	420	257	5	36	452	241	651	2e-78	268
rs:WP_032476424	DNA topoisomerase III [Vibrio cholerae].	40.00	350	203	1	36	385	255	597	2e-78	268
rs:WP_013973300	MULTISPECIES: DNA topoisomerase III [Pseudomonas putida group].	39.20	375	223	3	36	408	241	612	2e-78	268
rs:WP_017764797	MULTISPECIES: DNA topoisomerase III [Aeromonas].	37.71	411	236	6	36	435	249	650	2e-78	268
rs:WP_039576863	DNA topoisomerase III [Pseudomonas parafulva].	39.12	386	225	3	32	408	237	621	2e-78	268
rs:WP_008110346	DNA topoisomerase III [Pantoea sp. YR343].	40.57	350	200	3	36	385	251	592	3e-78	268
rs:WP_042012256	DNA topoisomerase III [Aeromonas fluvialis].	39.31	379	222	2	36	412	249	621	3e-78	268
rs:WP_023251690	DNA topoisomerase III, partial [Salmonella enterica].	38.57	350	207	3	36	385	6	347	3e-78	261
rs:WP_013745451	DNA topoisomerase III [Gallibacterium anatis].	38.35	352	209	2	36	387	261	604	3e-78	268
rs:WP_011345748	DNA topoisomerase TraE [Xanthomonas euvesicatoria].	35.82	469	250	11	32	454	259	722	3e-78	270
rs:WP_034946247	DNA topoisomerase III, partial [Gilliamella apicola].	37.96	353	218	1	36	387	257	609	3e-78	267
rs:WP_025240834	DNA topoisomerase III [Pseudomonas stutzeri].	37.97	374	229	2	36	408	242	613	3e-78	268
rs:WP_037048578	hypothetical protein, partial [Psychromonas sp. SP041].	37.91	401	227	4	36	436	255	633	3e-78	267
rs:WP_003190339	DNA topoisomerase III [Pseudomonas fluorescens].	38.24	374	228	2	36	408	241	612	3e-78	268
rs:WP_045161316	DNA topoisomerase III [Pseudomonas stutzeri].	36.95	387	242	2	23	408	229	614	3e-78	268
rs:WP_032886647	DNA topoisomerase III [Pseudomonas sp. RIT357].	38.50	374	227	2	36	408	241	612	3e-78	268
rs:WP_042825262	hypothetical protein [Xanthomonas axonopodis].	35.82	469	250	11	32	454	259	722	3e-78	269
rs:WP_047737517	DNA topoisomerase III [Enterobacter cloacae].	39.67	363	211	3	29	389	232	588	3e-78	266
rs:WP_032832845	DNA topoisomerase III [Pseudomonas sp. GM67].	37.80	381	219	3	61	436	267	634	3e-78	268
rs:WP_000197430	DNA topoisomerase III [Vibrio albensis].	39.71	350	204	1	36	385	255	597	3e-78	267
rs:WP_005786941	DNA topoisomerase III [Pseudomonas synxantha].	37.97	374	229	2	36	408	241	612	3e-78	267
rs:WP_042654335	DNA topoisomerase III [Aeromonas encheleia].	41.14	350	199	1	36	385	249	591	3e-78	268
rs:WP_046333399	DNA topoisomerase III [Pasteurella multocida].	35.61	410	252	4	5	414	238	635	3e-78	267
rs:WP_046885891	DNA topoisomerase III [Enterobacter cloacae].	38.06	402	227	6	36	436	251	631	3e-78	267
rs:WP_020798536	DNA topoisomerase III [Pseudomonas sp. G5(2012)].	37.80	381	219	3	61	436	267	634	4e-78	267
rs:WP_046101928	DNA topoisomerase III [Pantoea anthophila].	40.29	350	201	3	36	385	251	592	4e-78	267
rs:WP_007985230	DNA topoisomerase III [Paraglaciecola chathamensis].	40.00	350	201	1	36	385	254	594	4e-78	267
rs:WP_019485491	hypothetical protein, partial [Pseudomonas aeruginosa].	38.89	360	210	6	95	454	2	351	4e-78	259
rs:WP_028613339	DNA topoisomerase III [Pseudomonas putida].	38.93	375	224	3	36	408	241	612	4e-78	267
sp:TOP3_VIBCH	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	40.00	350	203	1	36	385	255	597	4e-78	267
rs:WP_032482725	DNA topoisomerase III [Vibrio cholerae].	40.00	350	203	1	36	385	255	597	4e-78	267
rs:WP_043153916	DNA topoisomerase III [Aeromonas sp. HZM].	39.71	350	204	2	36	385	249	591	4e-78	268
rs:WP_029615659	DNA topoisomerase III [Pseudomonas putida].	38.93	375	224	3	36	408	241	612	4e-78	267
tr:J2TJ40_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	37.80	381	219	3	61	436	270	637	4e-78	267
rs:WP_000197439	DNA topoisomerase III [Vibrio cholerae].	40.00	350	203	1	36	385	255	597	4e-78	267
rs:WP_036586587	DNA topoisomerase III [Ochrobactrum anthropi].	37.01	408	243	6	47	452	256	651	4e-78	268
rs:WP_040073611	DNA topoisomerase III [Vibrio cholerae].	40.00	350	203	1	36	385	255	597	4e-78	267
rs:WP_046817480	DNA topoisomerase III [Pseudomonas putida].	38.06	381	218	3	61	436	267	634	4e-78	267
rs:WP_003294153	DNA topoisomerase III [Pseudomonas stutzeri].	36.64	423	251	8	36	454	241	650	4e-78	268
rs:WP_048229605	DNA topoisomerase III [Enterobacter aerogenes].	39.89	366	212	3	29	392	232	591	4e-78	266
rs:WP_000197426	DNA topoisomerase III [Vibrio cholerae].	40.00	350	203	1	36	385	255	597	4e-78	267
rs:WP_045057706	DNA topoisomerase III [Pseudomonas sp. ES3-33].	38.06	381	218	3	61	436	267	634	4e-78	267
rs:WP_047962123	DNA topoisomerase III [Xenorhabdus khoisanae].	40.17	361	199	5	36	391	251	599	4e-78	267
rs:WP_037353159	DNA topoisomerase III, partial [Salinivibrio socompensis].	40.00	350	202	2	36	385	251	592	4e-78	267
rs:WP_042803655	DNA topoisomerase III [Mannheimia haemolytica].	38.86	350	206	2	36	385	252	593	4e-78	267
rs:WP_014326230	DNA topoisomerase III [Pasteurella multocida].	35.61	410	252	4	5	414	238	635	4e-78	267
rs:WP_008435880	DNA topoisomerase III [Pseudomonas sp. Ag1].	36.61	407	239	4	36	436	241	634	4e-78	267
rs:WP_023155789	DNA topoisomerase III [Escherichia coli].	38.40	388	224	4	29	414	232	606	5e-78	266
rs:WP_038270179	DNA topoisomerase III [Xenorhabdus cabanillasii].	39.55	354	198	4	36	385	251	592	5e-78	267
rs:WP_026949894	DNA topoisomerase III [Alcanivorax sp. 43B_GOM-46m].	35.95	420	250	4	36	436	247	666	5e-78	268
rs:WP_031613135	DNA topoisomerase III, partial [Salmonella enterica].	38.57	350	207	3	36	385	39	380	5e-78	261
rs:WP_027074724	DNA topoisomerase III [Mannheimia granulomatis].	38.86	350	206	2	36	385	252	593	5e-78	267
rs:WP_014108299	DNA topoisomerase III [Glaciecola nitratireducens].	38.57	350	211	1	36	385	251	596	5e-78	267
tr:F3FB75_PSEA0	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	37.97	424	250	5	31	452	64	476	5e-78	263
rs:WP_012073435	DNA topoisomerase III [Actinobacillus succinogenes].	38.21	369	220	2	36	404	254	614	5e-78	267
rs:WP_044273187	DNA topoisomerase III [Pseudomonas fluorescens].	37.66	385	232	3	36	414	241	623	5e-78	267
rs:WP_034148898	DNA topoisomerase III [Pseudomonas fluorescens].	37.80	381	219	3	61	436	267	634	5e-78	267
rs:WP_021248574	DNA topoisomerase III [Thauera terpenica].	36.77	427	253	8	32	454	237	650	5e-78	268
rs:WP_010172260	DNA topoisomerase III [Pseudomonas sp. PAMC 25886].	36.61	407	239	4	36	436	241	634	5e-78	267
rs:WP_024074508	DNA topoisomerase III [Pseudomonas sp. TKP].	37.63	388	228	4	36	414	241	623	5e-78	267
rs:WP_011707714	DNA topoisomerase III [Aeromonas hydrophila].	39.08	371	216	3	36	403	249	612	5e-78	267
rs:WP_016958405	DNA topoisomerase III [Enterovibrio norvegicus].	39.30	369	217	3	36	404	251	612	5e-78	267
rs:WP_040045076	DNA topoisomerase III [Hafnia alvei].	40.29	350	201	3	36	385	251	592	5e-78	267
rs:WP_034112916	DNA topoisomerase III [Pseudomonas fluorescens].	39.83	359	209	2	61	414	267	623	5e-78	267
rs:WP_013692761	DNA topoisomerase III [Pseudomonas brassicacearum].	35.31	422	257	6	36	454	241	649	5e-78	267
rs:WP_028699042	DNA topoisomerase III [Pseudomonas monteilii].	38.93	375	224	3	36	408	241	612	6e-78	267
rs:WP_008897065	DNA topoisomerase III [Rheinheimera sp. A13L].	37.63	388	237	3	19	403	229	614	6e-78	267
rs:WP_024032345	DNA topoisomerase III [Pseudoalteromonas sp. NW 4327].	41.14	350	197	2	36	385	251	591	6e-78	267
rs:WP_033114850	DNA topoisomerase III [Aeromonas lacus].	38.79	379	224	2	36	412	249	621	6e-78	267
rs:WP_004394830	DNA topoisomerase III [Vibrio metschnikovii].	38.21	369	221	1	36	404	255	616	6e-78	267
rs:WP_042025194	DNA topoisomerase III [Aeromonas enteropelogenes].	40.00	350	204	1	36	385	249	592	6e-78	267
rs:WP_004093052	DNA topoisomerase III [Hafnia alvei].	40.29	350	201	3	36	385	251	592	6e-78	266
rs:WP_045292289	DNA topoisomerase III [Enterobacter sp. 42324].	38.48	382	229	2	29	409	232	608	6e-78	266
rs:WP_027903059	DNA topoisomerase III [Pseudomonas sp. URMO17WK12:I3].	37.47	387	239	2	23	408	228	612	6e-78	267
rs:WP_045631099	DNA topoisomerase III [Enterobacter cloacae].	39.94	363	210	3	29	389	232	588	6e-78	266
rs:WP_046602256	DNA topoisomerase III [Pseudomonas aeruginosa].	36.04	444	258	7	31	459	236	668	6e-78	268
rs:WP_044707711	DNA topoisomerase III, partial [Escherichia coli].	38.57	350	207	3	36	385	43	384	6e-78	261
rs:WP_014717974	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	38.24	374	228	2	36	408	241	612	6e-78	267
rs:WP_032881001	DNA topoisomerase III [Pseudomonas sp. BRG-100].	37.97	374	229	2	36	408	241	612	6e-78	267
rs:WP_004586877	DNA topoisomerase III [Pseudoalteromonas agarivorans].	41.14	350	197	2	36	385	251	591	6e-78	266
rs:WP_039334584	DNA topoisomerase III [Pantoea rodasii].	37.66	393	229	4	36	420	251	635	6e-78	266
rs:WP_012277719	DNA topoisomerase III [Shewanella halifaxensis].	37.71	358	216	1	35	385	250	607	6e-78	267
rs:WP_011051421	DNA topoisomerase III [Xanthomonas citri].	35.35	430	255	7	36	454	238	655	6e-78	267
rs:WP_032106904	DNA topoisomerase III, partial [Escherichia coli].	38.57	350	207	3	36	385	12	353	6e-78	260
rs:WP_015463225	MULTISPECIES: DNA topoisomerase III [Xanthomonas].	35.35	430	255	7	36	454	241	658	7e-78	267
rs:WP_040076043	DNA topoisomerase III [Enterobacteriaceae bacterium ATCC 29904].	38.06	402	227	6	36	436	251	631	7e-78	266
rs:WP_033042013	DNA topoisomerase III [Pseudomonas putida].	39.37	348	209	1	61	408	267	612	7e-78	266
rs:WP_023008797	DNA topoisomerase III [Marinobacter sp. EVN1].	36.36	473	251	5	30	459	248	713	7e-78	268
rs:WP_010954821	DNA topoisomerase III [Pseudomonas putida].	38.93	375	224	3	36	408	241	612	7e-78	267
rs:WP_007997338	DNA topoisomerase III [Pseudomonas sp. GM49].	39.11	358	212	2	61	414	270	625	7e-78	266
rs:WP_045958510	DNA topoisomerase III [Xenorhabdus poinarii].	40.34	357	204	4	36	391	251	599	7e-78	266
rs:WP_047538489	DNA topoisomerase III [Pseudomonas sp. 11/12A].	37.53	381	220	3	61	436	267	634	7e-78	266
rs:WP_043105734	DNA topoisomerase III [Pseudomonas aeruginosa].	36.17	423	253	7	36	454	241	650	7e-78	267
rs:WP_023534787	DNA topoisomerase III [Pseudomonas putida].	37.56	418	239	5	36	435	241	654	7e-78	267
rs:WP_038233707	DNA topoisomerase III [Xenorhabdus szentirmaii].	40.44	361	198	5	36	391	251	599	7e-78	266
rs:WP_047050492	DNA topoisomerase III [Enterobacter aerogenes].	39.94	363	210	3	29	389	232	588	7e-78	266
rs:WP_038643496	DNA topoisomerase III [Pantoea rwandensis].	38.61	417	242	6	36	450	242	646	7e-78	267
tr:W1AZV1_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	38.57	350	207	3	36	385	35	376	7e-78	261
rs:WP_035685029	DNA topoisomerase III [Avibacterium paragallinarum].	38.57	350	208	2	36	385	253	595	7e-78	266
rs:WP_038473424	DNA topoisomerase III [Cedecea neteri].	38.48	369	219	3	36	404	251	611	7e-78	267
rs:WP_032897514	DNA topoisomerase III [Pseudomonas sp. Eur1 9.41].	38.24	374	228	2	36	408	241	612	7e-78	266
rs:WP_034127261	DNA topoisomerase III [Pseudomonas fluorescens].	37.97	374	229	2	36	408	241	612	7e-78	266
rs:WP_042031860	DNA topoisomerase III [Aeromonas jandaei].	39.05	379	223	2	36	412	249	621	7e-78	267
rs:WP_010846042	DNA topoisomerase III [Xenorhabdus nematophila].	39.61	361	201	5	36	391	251	599	7e-78	266
rs:WP_038192148	DNA topoisomerase III [Xenorhabdus bovienii].	40.34	357	204	4	36	391	251	599	8e-78	266
rs:WP_045716821	DNA topoisomerase III, partial [Salmonella enterica].	38.57	350	207	3	36	385	44	385	8e-78	261
rs:WP_047882560	DNA topoisomerase III [Pseudomonas sp. ARP3].	40.28	355	205	2	65	414	271	623	8e-78	266
rs:WP_041409827	DNA topoisomerase III [Shewanella amazonensis].	37.14	412	252	3	32	438	247	656	8e-78	267
rs:WP_008028166	DNA topoisomerase III [Pseudomonas sp. GM60].	37.80	381	219	3	61	436	267	634	8e-78	266
rs:WP_023047535	DNA topoisomerase III [Pseudomonas putida].	37.44	390	226	7	67	454	272	645	8e-78	266
rs:WP_039575248	DNA topoisomerase III [Xanthomonas axonopodis].	36.47	425	255	7	32	452	237	650	8e-78	267
tr:X2H3M2_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	35.04	371	241	0	36	406	257	627	8e-78	266
rs:WP_016392731	DNA topoisomerase III [Pseudomonas plecoglossicida].	38.93	375	224	3	36	408	241	612	8e-78	266
tr:A0A0A2VYV2_BEABA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	38.21	369	220	3	36	404	164	524	8e-78	265
rs:WP_008059727	DNA topoisomerase III [Pseudomonas sp. GM78].	37.80	381	219	3	61	436	267	634	8e-78	266
rs:WP_038208626	DNA topoisomerase III [Xenorhabdus bovienii].	40.34	357	204	4	36	391	251	599	8e-78	266
rs:WP_042059062	DNA topoisomerase III [Acidomonas methanolica].	36.82	421	253	6	36	454	241	650	8e-78	267
rs:WP_013184475	DNA topoisomerase III [Xenorhabdus nematophila].	39.61	361	201	5	36	391	251	599	8e-78	266
rs:WP_036832004	DNA topoisomerase III, partial [Photobacterium sanctipauli].	42.15	325	183	1	32	356	247	566	9e-78	264
rs:WP_018611357	DNA topoisomerase III [Pseudomonas sp. CFII68].	36.80	413	252	4	31	436	236	646	9e-78	266
rs:WP_038218184	DNA topoisomerase III [Xenorhabdus bovienii].	40.34	357	204	4	36	391	251	599	9e-78	266
rs:WP_038518007	DNA topoisomerase III, partial [Gilliamella apicola].	35.04	371	241	0	36	406	257	627	9e-78	266
rs:WP_010566039	DNA topoisomerase III [Pseudomonas extremaustralis].	38.44	385	229	3	36	414	241	623	9e-78	266
rs:WP_008046973	DNA topoisomerase III [Pseudomonas sp. GM74].	39.39	358	211	2	61	414	270	625	9e-78	266
rs:WP_038254850	DNA topoisomerase III [Xenorhabdus bovienii].	40.34	357	204	4	36	391	251	599	1e-77	266
rs:WP_034135351	DNA topoisomerase III [Pseudomonas fluorescens].	38.24	374	228	2	36	408	241	612	1e-77	266
rs:WP_037072304	DNA topoisomerase III [Psychromonas arctica].	38.11	370	214	2	36	405	253	607	1e-77	266
rs:WP_019821417	DNA topoisomerase III [Pseudomonas sp. CFT9].	37.97	374	229	2	36	408	241	612	1e-77	266
rs:WP_010786935	DNA topoisomerase III [[Haemophilus] parasuis].	39.14	350	206	1	36	385	252	594	1e-77	266
rs:WP_005709182	DNA topoisomerase III [Haemophilus paraphrohaemolyticus].	39.14	350	205	2	36	385	252	593	1e-77	266
rs:WP_019530976	hypothetical protein [Dasania marina].	37.29	354	220	1	32	385	247	598	1e-77	266
rs:WP_045511565	DNA topoisomerase III [Kosakonia oryzae].	37.44	398	240	4	36	433	251	639	1e-77	266
rs:WP_028115166	DNA topoisomerase III [Ferrimonas senticii].	40.88	340	192	2	35	374	250	580	1e-77	266
rs:WP_033779068	DNA topoisomerase III [Pantoea agglomerans].	40.29	350	201	3	36	385	251	592	1e-77	266
rs:WP_012533717	DNA topoisomerase III [Aliivibrio fischeri].	37.67	369	226	2	36	404	268	632	1e-77	266
rs:WP_027909879	DNA topoisomerase III [Pseudomonas sp. URMO17WK12:I4].	37.21	387	240	2	23	408	228	612	1e-77	266
rs:WP_043544899	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	39.61	356	202	5	103	454	1	347	1e-77	258
rs:WP_030137934	DNA topoisomerase III [Pseudomonas fluorescens].	37.44	390	236	3	31	414	236	623	1e-77	266
tr:A1S7J4_SHEAM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.14	412	252	3	32	438	271	680	1e-77	267
rs:WP_016954622	DNA topoisomerase III [Catenovulum agarivorans].	38.44	359	212	2	36	386	249	606	1e-77	267
rs:WP_012988871	DNA topoisomerase III [Xenorhabdus bovienii].	40.34	357	204	4	36	391	251	599	1e-77	266
rs:WP_013345169	DNA topoisomerase III [Ferrimonas balearica].	39.14	373	219	2	32	404	246	610	1e-77	266
rs:WP_038224744	DNA topoisomerase III [Xenorhabdus bovienii].	40.34	357	204	4	36	391	251	599	1e-77	266
rs:WP_021724503	DNA topoisomerase III [Avibacterium paragallinarum].	38.86	350	207	2	36	385	253	595	1e-77	266
rs:WP_033757863	DNA topoisomerase III [Pantoea agglomerans].	40.29	350	201	3	36	385	251	592	1e-77	266
rs:WP_000197435	DNA topoisomerase III [Vibrio cholerae].	39.71	350	204	1	36	385	255	597	1e-77	266
rs:WP_038188930	DNA topoisomerase III [Xenorhabdus bovienii].	40.34	357	204	4	36	391	251	599	1e-77	266
rs:WP_028632332	DNA topoisomerase III [Pseudomonas parafulva].	40.64	342	201	1	67	408	273	612	1e-77	266
rs:WP_045715460	DNA topoisomerase III, partial [Salmonella enterica].	38.57	350	207	3	36	385	61	402	1e-77	261
rs:WP_010260636	MULTISPECIES: DNA topoisomerase III [Pantoea].	40.29	350	201	3	36	385	251	592	1e-77	266
rs:WP_032724076	DNA topoisomerase III [Enterobacter aerogenes].	38.66	388	223	4	29	414	232	606	1e-77	265
rs:WP_043850762	DNA topoisomerase III [Aeromonas sp. L_1B5_3].	38.79	379	224	2	36	412	249	621	1e-77	266
rs:WP_014338649	DNA topoisomerase III [Pseudomonas fluorescens].	36.80	413	252	4	31	436	236	646	1e-77	266
rs:WP_031667774	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	36.04	444	258	7	31	459	236	668	1e-77	267
rs:WP_013095152	DNA topoisomerase III [Enterobacter cloacae].	40.64	374	215	4	36	406	242	611	1e-77	267
rs:WP_031592756	DNA topoisomerase III [Pantoea agglomerans].	40.29	350	201	3	36	385	251	592	1e-77	266
rs:WP_039165985	DNA topoisomerase III [Gallibacterium anatis].	37.75	355	213	2	36	390	261	607	1e-77	266
rs:WP_033771944	DNA topoisomerase III [Pantoea agglomerans].	40.29	350	201	3	36	385	251	592	1e-77	266
rs:WP_028862617	DNA topoisomerase III [Psychromonas aquimarina].	38.29	350	205	2	36	385	254	592	1e-77	265
rs:WP_046457683	DNA topoisomerase III [Hafnia alvei].	40.00	350	202	3	36	385	251	592	1e-77	266
rs:WP_013724181	DNA topoisomerase III [Aeromonas veronii].	38.79	379	224	2	36	412	249	621	1e-77	266
rs:WP_032551967	DNA topoisomerase III [Vibrio fortis].	38.66	357	214	1	36	392	255	606	1e-77	266
rs:WP_012621725	DNA topoisomerase III [Haemophilus parasuis].	39.14	350	206	1	36	385	252	594	1e-77	265
rs:WP_034028189	DNA topoisomerase III [Pseudomonas aeruginosa].	36.04	444	258	7	31	459	236	668	2e-77	267
rs:WP_001728503	DNA topoisomerase III [Salmonella enterica].	38.66	388	223	4	29	414	232	606	2e-77	265
rs:WP_036793769	DNA topoisomerase III [Photobacterium phosphoreum].	37.32	351	217	1	35	385	250	597	2e-77	265
rs:WP_043893430	DNA topoisomerase III, partial [Osedax symbiont Rs2].	39.74	380	220	3	20	399	238	608	2e-77	265
sp:TOP3_PASMU	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	35.75	400	245	4	5	404	238	625	2e-77	266
rs:WP_017904483	DNA topoisomerase III [Pseudomonas fuscovaginae].	38.46	377	227	2	61	434	267	641	2e-77	266
rs:WP_040230287	DNA topoisomerase III [Citrobacter sp. CIP 55.13].	39.36	376	220	3	29	402	232	601	2e-77	265
tr:A0A0C5VKB9_9ENTR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	40.00	350	202	3	36	385	251	592	2e-77	265
rs:WP_029613131	DNA topoisomerase III [Pseudomonas sp. ICMP 17674].	39.18	388	224	4	32	408	237	623	2e-77	266
rs:WP_033699921	DNA topoisomerase III [Pseudomonas sp. WCS358].	39.47	375	222	3	36	408	241	612	2e-77	266
rs:WP_017475477	DNA topoisomerase III [Pseudomonas sp. PAMC 26793].	37.97	374	229	2	36	408	241	612	2e-77	266
rs:WP_007889711	DNA topoisomerase III [Pantoea sp. GM01].	40.00	350	202	3	36	385	251	592	2e-77	265
rs:WP_047581877	DNA topoisomerase III [Pseudomonas sp. H2].	39.47	375	222	3	36	408	241	612	2e-77	266
rs:WP_000197434	DNA topoisomerase III [Vibrio cholerae].	39.71	350	204	1	36	385	255	597	2e-77	265
rs:WP_042927335	MULTISPECIES: DNA topoisomerase III [Pseudomonas stutzeri group].	35.87	421	259	5	35	454	240	650	2e-77	266
rs:WP_008077315	DNA topoisomerase III [Pseudomonas sp. GM80].	39.39	358	211	2	61	414	267	622	2e-77	265
rs:WP_005756024	DNA topoisomerase III [Pasteurella multocida].	35.75	400	245	4	5	404	238	625	2e-77	265
rs:WP_039090578	DNA topoisomerase III [Gallibacterium anatis].	37.75	355	213	2	36	390	261	607	2e-77	265
rs:WP_005341866	DNA topoisomerase III [Aeromonas veronii].	38.52	379	225	2	36	412	249	621	2e-77	266
rs:WP_005419931	DNA topoisomerase III [Aliivibrio fischeri].	37.67	369	226	2	36	404	268	632	2e-77	266
tr:A4NVD0_HAEIF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.94	369	221	2	36	404	174	534	2e-77	263
rs:WP_042017937	DNA topoisomerase III [Aeromonas sobria].	39.05	379	223	2	36	412	249	621	2e-77	266
rs:WP_014391307	DNA topoisomerase III [Pasteurella multocida].	35.75	400	245	4	5	404	238	625	2e-77	265
rs:WP_017124649	DNA topoisomerase III [Pseudomonas gingeri].	38.16	380	228	2	60	434	266	643	2e-77	265
rs:WP_031423960	DNA topoisomerase III [Xanthomonas axonopodis].	35.22	423	263	5	32	452	237	650	2e-77	266
rs:WP_042559616	DNA topoisomerase III [Pseudomonas fluorescens].	38.26	379	227	3	61	434	267	643	2e-77	265
rs:WP_005723459	DNA topoisomerase III [Pasteurella multocida].	36.00	400	244	4	5	404	238	625	2e-77	265
rs:WP_024960796	DNA topoisomerase III [Pseudomonas syringae].	38.44	424	248	5	31	452	236	648	2e-77	266
rs:WP_045782181	DNA topoisomerase III [Klebsiella michiganensis].	38.21	369	220	3	36	404	251	611	2e-77	266
rs:WP_017243165	DNA topoisomerase III [Vibrio breoganii].	37.94	369	222	3	36	404	255	616	2e-77	265
rs:WP_045786180	DNA topoisomerase III [Ralstonia mannitolilytica].	35.93	423	254	8	36	454	241	650	2e-77	266
rs:WP_040078239	DNA topoisomerase III, partial [Escherichia coli].	40.50	358	196	4	97	450	9	353	2e-77	258
rs:WP_039694986	DNA topoisomerase III [Dickeya solani].	35.84	399	246	4	61	459	267	655	2e-77	265
rs:WP_004576972	DNA topoisomerase III [Pseudomonas putida].	38.93	375	224	3	36	408	241	612	2e-77	265
rs:WP_017006904	DNA topoisomerase III [Enterovibrio norvegicus].	39.02	369	218	3	36	404	251	612	3e-77	265
rs:WP_042467760	DNA topoisomerase III [Aeromonas salmonicida].	40.29	350	203	1	36	385	249	592	3e-77	265
rs:WP_027966602	DNA topoisomerase III [Halomonas halocynthiae].	36.75	381	238	1	35	415	250	627	3e-77	265
rs:WP_014590367	DNA topoisomerase III [Pseudomonas putida].	38.67	375	225	3	36	408	241	612	3e-77	265
rs:WP_041982760	DNA topoisomerase III [Xenorhabdus nematophila].	37.98	416	244	6	36	449	242	645	3e-77	266
rs:WP_010618764	DNA topoisomerase III [Plautia stali symbiont].	40.00	350	202	3	36	385	251	592	3e-77	265
rs:WP_043823102	DNA topoisomerase III [Aeromonas veronii].	39.71	350	205	1	36	385	249	592	3e-77	265
tr:A0A080KKI8_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.77	371	242	0	36	406	257	627	3e-77	265
rs:WP_042074080	DNA topoisomerase III, partial [Escherichia coli].	35.66	401	239	4	36	436	114	495	3e-77	261
rs:WP_026031846	DNA topoisomerase III [Pseudomonas putida].	38.67	375	225	3	36	408	241	612	3e-77	265
rs:WP_032214543	DNA topoisomerase III [Escherichia coli].	39.01	382	227	2	29	409	232	608	3e-77	264
rs:WP_018929752	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	38.06	381	218	3	61	436	267	634	3e-77	265
rs:WP_041030302	DNA topoisomerase III, partial [Salmonella enterica].	38.57	350	207	3	36	385	114	455	3e-77	261
rs:WP_039151066	DNA topoisomerase III [Gallibacterium anatis].	38.07	352	210	2	36	387	261	604	3e-77	265
rs:WP_045227513	DNA topoisomerase III, partial [Escherichia coli].	38.57	350	207	3	36	385	90	431	3e-77	261
tr:W1H5Z8_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	39.03	351	204	4	36	385	57	398	3e-77	259
rs:WP_019446465	DNA topoisomerase III [Aeromonas sp. 159].	38.79	379	224	2	36	412	249	621	3e-77	265
rs:WP_011829934	DNA topoisomerase III [Methylibium petroleiphilum].	36.29	394	241	6	61	454	267	650	3e-77	265
rs:WP_005318526	DNA topoisomerase III [Aeromonas salmonicida].	40.29	350	203	1	36	385	249	592	3e-77	265
rs:WP_008456652	DNA topoisomerase III [Enterobacter sp. Ag1].	39.43	350	204	3	36	385	251	592	3e-77	265
rs:WP_007180672	DNA topoisomerase III [Burkholderia sp. Ch1-1].	36.36	418	255	6	36	452	241	648	3e-77	265
rs:WP_024105857	MULTISPECIES: DNA topoisomerase III [Dickeya].	37.87	375	224	4	36	409	251	617	3e-77	265
rs:WP_021109548	DNA topoisomerase III [[Haemophilus] parasuis].	39.14	350	205	2	36	385	252	593	3e-77	265
rs:WP_025854478	DNA topoisomerase III [Pseudomonas sp. CHM02].	38.24	374	228	2	36	408	241	612	4e-77	265
tr:G5Q3L3_SALMO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	38.57	350	207	3	36	385	76	417	4e-77	261
rs:WP_005751158	DNA topoisomerase III [Pasteurella multocida].	35.37	410	253	4	5	414	238	635	4e-77	265
rs:WP_027916196	DNA topoisomerase III [Pseudomonas sp. URMO17WK12:I11].	40.06	342	203	1	67	408	273	612	4e-77	265
rs:WP_022997579	hypothetical protein [Alcanivorax sp. PN-3].	37.20	422	242	7	36	436	247	666	4e-77	266
rs:WP_040269467	DNA topoisomerase III [Pseudomonas rhodesiae].	39.55	359	210	2	61	414	267	623	4e-77	265
rs:WP_017350143	DNA topoisomerase III [Pasteurella multocida].	35.37	410	253	4	5	414	238	635	4e-77	265
rs:WP_047703657	DNA topoisomerase III [Pseudomonas mediterranea].	37.47	387	237	3	31	414	236	620	4e-77	265
rs:WP_004362285	DNA topoisomerase III [Thauera phenylacetica].	35.70	423	255	6	36	454	241	650	4e-77	265
rs:WP_047149922	DNA topoisomerase III [Pseudomonas sp. TJI-51].	39.20	375	223	3	36	408	241	612	4e-77	265
rs:WP_042078806	DNA topoisomerase III [Aeromonas sanarellii].	40.57	350	201	2	36	385	249	591	4e-77	265
tr:W1E140_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	39.03	351	204	4	36	385	42	383	4e-77	259
rs:WP_003173078	DNA topoisomerase III [Pseudomonas fluorescens].	36.19	409	253	3	36	438	241	647	4e-77	265
rs:WP_040070032	DNA topoisomerase III [Aeromonas veronii].	38.79	379	224	2	36	412	249	621	5e-77	265
rs:WP_042644457	DNA topoisomerase III [Aeromonas eucrenophila].	40.29	350	203	1	36	385	249	592	5e-77	265
rs:WP_003413130	DNA topoisomerase III [Pseudomonas syringae].	34.75	423	265	4	32	452	237	650	5e-77	265
rs:WP_046483316	DNA topoisomerase III [Pseudomonas veronii].	38.24	374	228	2	36	408	241	612	5e-77	265
tr:J2RM32_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	39.11	358	212	2	61	414	267	622	5e-77	264
rs:WP_028686538	DNA topoisomerase III [Pseudomonas fulva].	40.06	342	203	1	67	408	273	612	5e-77	265
rs:WP_005339851	DNA topoisomerase III [Aeromonas veronii].	38.79	379	224	2	36	412	249	621	5e-77	265
rs:WP_042095835	DNA topoisomerase III, partial [Escherichia coli].	38.57	350	207	3	36	385	116	457	5e-77	261
tr:V1S057_SALET	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	38.57	350	207	3	36	385	123	464	5e-77	261
rs:WP_015270975	DNA topoisomerase III [Pseudomonas putida].	39.47	375	222	3	36	408	241	612	6e-77	264
rs:WP_033063590	DNA topoisomerase III [Pseudomonas sp. GM48].	39.11	358	212	2	61	414	270	625	6e-77	264
rs:WP_014668193	DNA topoisomerase III [Pasteurella multocida].	35.75	400	245	4	5	404	238	625	6e-77	264
rs:WP_023603551	DNA topoisomerase III [Aliivibrio logei].	36.29	383	237	3	22	404	248	623	6e-77	264
rs:WP_017530498	DNA topoisomerase III [Pseudomonas fluorescens].	38.18	385	230	3	36	414	241	623	6e-77	264
rs:WP_023198293	DNA topoisomerase III, partial [Salmonella enterica].	38.33	347	206	3	39	385	2	340	6e-77	257
rs:WP_012273226	DNA topoisomerase III [Pseudomonas putida].	38.67	375	225	3	36	408	241	612	6e-77	264
rs:WP_024666679	DNA topoisomerase III, partial [Pseudomonas syringae].	38.48	356	217	1	61	416	149	502	6e-77	261
rs:WP_011199909	DNA topoisomerase III [[Mannheimia] succiniciproducens].	38.21	369	220	2	36	404	253	613	6e-77	264
rs:WP_036131029	DNA topoisomerase III [Marinobacter sp. AK21].	37.15	471	246	9	32	459	250	713	6e-77	266
rs:WP_039767094	DNA topoisomerase III [Pseudomonas fluorescens].	38.55	358	214	2	61	414	267	622	6e-77	264
rs:WP_026013519	DNA topoisomerase III [Pseudomonas fluorescens].	38.50	374	227	2	36	408	241	612	6e-77	264
rs:WP_047037701	DNA topoisomerase III [Enterobacter aerogenes].	39.14	350	205	3	36	385	251	592	6e-77	264
rs:WP_025802043	DNA topoisomerase III [Hafnia alvei].	39.71	350	203	3	36	385	251	592	6e-77	264
tr:K9NKF5_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	39.11	358	212	2	61	414	267	622	6e-77	264
rs:WP_006995139	MULTISPECIES: DNA topoisomerase III [Haemophilus].	38.21	369	220	2	36	404	260	620	7e-77	264
rs:WP_034097216	DNA topoisomerase III [Pseudomonas fluorescens].	39.28	359	211	2	61	414	267	623	7e-77	264
rs:WP_043004022	DNA topoisomerase III, partial [Vibrio anguillarum].	39.12	340	204	1	35	374	250	586	7e-77	263
rs:WP_041474889	DNA topoisomerase III [Pseudomonas sp. UW4].	39.11	358	212	2	61	414	270	625	7e-77	264
rs:WP_039613170	DNA topoisomerase III [Pseudomonas sp. C5pp].	39.47	375	222	3	36	408	241	612	7e-77	264
rs:WP_039127867	DNA topoisomerase III, partial [Gilliamella apicola].	36.57	350	222	0	36	385	257	606	7e-77	263
rs:WP_034137853	DNA topoisomerase III [Pseudomonas fluorescens].	39.28	359	211	2	61	414	267	623	7e-77	264
rs:WP_039058176	DNA topoisomerase III [Enterobacter sp. Bisph1].	36.82	402	245	4	36	437	251	643	7e-77	264
tr:W1HVM3_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	39.03	351	204	4	36	385	57	398	7e-77	259
rs:WP_039147192	DNA topoisomerase III [Gallibacterium anatis].	37.46	355	214	2	36	390	261	607	7e-77	264
rs:WP_005357612	DNA topoisomerase III [Aeromonas veronii].	38.79	379	224	2	36	412	249	621	7e-77	264
rs:WP_034914838	DNA topoisomerase III, partial [Gilliamella apicola].	35.03	374	242	1	36	408	257	630	7e-77	263
rs:WP_013260124	DNA topoisomerase III [gamma proteobacterium HdN1].	38.86	350	210	3	36	385	267	612	7e-77	265
rs:WP_021139862	DNA topoisomerase III [Aeromonas salmonicida].	38.50	400	231	4	36	435	249	633	7e-77	264
rs:WP_038409959	MULTISPECIES: DNA topoisomerase III [Pseudomonas putida group].	39.47	375	222	3	36	408	241	612	8e-77	264
rs:WP_029296576	DNA topoisomerase III [Pseudomonas fluorescens].	36.61	407	239	4	36	436	241	634	8e-77	264
rs:WP_019442553	DNA topoisomerase III [Moritella marina].	37.50	352	219	1	35	385	250	601	8e-77	264
rs:WP_012051818	DNA topoisomerase III [Pseudomonas putida].	38.67	375	225	3	36	408	241	612	8e-77	264
rs:WP_005753511	DNA topoisomerase III [Pasteurella multocida].	35.37	410	253	4	5	414	238	635	8e-77	264
rs:WP_027608787	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	38.77	374	224	3	36	407	241	611	8e-77	264
rs:WP_025753452	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	38.77	374	224	3	36	407	241	611	8e-77	264
rs:WP_026020317	DNA topoisomerase III [Pseudomonas putida].	38.77	374	224	3	36	407	241	611	8e-77	264
rs:WP_012550681	DNA topoisomerase III [Aliivibrio salmonicida].	36.55	383	236	3	22	404	248	623	8e-77	264
rs:WP_044599963	DNA topoisomerase III [Cronobacter sakazakii].	37.09	399	237	4	36	434	251	635	8e-77	264
rs:WP_014755959	DNA topoisomerase III [Pseudomonas putida].	38.67	375	225	3	36	408	241	612	9e-77	264
rs:WP_031597904	DNA topoisomerase III, partial [Pseudomonas savastanoi].	41.21	364	210	3	31	392	236	597	9e-77	263
rs:WP_046062077	DNA topoisomerase III [Pseudomonas kilonensis].	36.50	411	252	4	31	434	236	644	9e-77	264
rs:WP_034152903	DNA topoisomerase III [Pseudomonas fluorescens].	39.77	347	207	1	61	407	267	611	1e-76	263
rs:WP_019484713	hypothetical protein, partial [Pseudomonas aeruginosa].	37.22	360	216	5	95	454	2	351	1e-76	256
rs:WP_039292251	DNA topoisomerase III [Cedecea neteri].	39.43	350	204	3	36	385	251	592	1e-76	264
rs:WP_005298337	DNA topoisomerase III [Photobacterium damselae].	39.29	364	215	2	36	396	251	611	1e-76	264
rs:WP_045525843	DNA topoisomerase III [Aeromonas hydrophila].	39.53	382	219	5	36	414	249	621	1e-76	264
rs:WP_034951136	DNA topoisomerase III, partial [Erwinia oleae].	42.35	340	185	5	111	450	2	330	1e-76	255
rs:WP_025339781	DNA topoisomerase III [Pseudomonas sp. FGI182].	39.47	375	222	3	36	408	241	612	1e-76	263
rs:WP_028723486	DNA topoisomerase III [Pantoea ananatis].	40.29	350	201	3	36	385	251	592	1e-76	263
rs:WP_041637066	DNA topoisomerase III, partial [Acidithiobacillus caldus].	42.09	373	198	7	31	399	224	582	1e-76	262
rs:WP_045721118	DNA topoisomerase III, partial [Salmonella enterica].	38.57	350	207	3	36	385	142	483	1e-76	261
rs:WP_014853514	DNA topoisomerase III [Pseudomonas stutzeri].	35.92	387	245	2	23	408	228	612	1e-76	263
rs:WP_034790651	DNA topoisomerase III [Ewingella americana].	38.50	374	218	5	36	407	251	614	1e-76	263
tr:F2B8G7_9NEIS	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	38.79	379	220	5	36	403	244	621	1e-76	263
rs:WP_038904435	DNA topoisomerase III [Dickeya zeae].	36.91	382	232	4	36	417	251	623	1e-76	263
rs:WP_041997876	DNA topoisomerase III [Aeromonas bivalvium].	38.02	405	241	3	36	437	249	646	1e-76	264
rs:WP_047604809	DNA topoisomerase III [Pseudomonas putida].	38.67	375	225	3	36	408	241	612	1e-76	263
rs:WP_044710862	DNA topoisomerase III [Escherichia coli].	39.14	350	205	3	36	385	251	592	1e-76	263
rs:WP_017022826	DNA topoisomerase III [Aliivibrio logei].	36.29	383	237	3	22	404	257	632	1e-76	263
rs:WP_040404641	DNA topoisomerase III, partial [Amphritea japonica].	37.70	366	214	2	36	399	251	604	1e-76	262
rs:WP_011609464	DNA topoisomerase III [Histophilus somni].	35.00	400	249	3	9	408	229	617	1e-76	263
rs:WP_038922734	DNA topoisomerase III [Dickeya dadantii].	37.60	375	225	4	36	409	251	617	1e-76	263
rs:WP_032468723	DNA topoisomerase III [Vibrio mimicus].	37.10	372	227	1	36	407	255	619	1e-76	263
rs:WP_035496709	DNA topoisomerase III [[Haemophilus] parasuis].	39.14	350	205	2	36	385	252	593	1e-76	263
rs:WP_021118952	DNA topoisomerase III [[Haemophilus] parasuis].	39.14	350	205	2	36	385	252	593	1e-76	263
rs:WP_001682942	DNA topoisomerase III [Escherichia coli].	38.86	350	206	3	36	385	251	592	1e-76	263
rs:WP_045083314	MULTISPECIES: DNA topoisomerase III [Photobacterium].	39.43	350	207	2	36	385	251	595	1e-76	263
tr:A0A087FB29_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	35.61	424	255	8	32	454	237	643	1e-76	263
rs:WP_033078756	DNA topoisomerase III [Thalassotalea sp. ND16A].	38.64	352	215	1	35	386	250	600	1e-76	263
rs:WP_012884825	DNA topoisomerase III [Dickeya dadantii].	37.24	384	228	5	36	414	250	625	1e-76	263
rs:WP_038911181	DNA topoisomerase III [Dickeya dadantii].	37.60	375	225	4	36	409	251	617	2e-76	263
rs:WP_023639754	DNA topoisomerase III [Dickeya zeae].	36.91	382	232	4	36	417	251	623	2e-76	263
rs:WP_039763141	DNA topoisomerase III [Pseudomonas fluorescens].	37.33	375	229	2	61	431	267	639	2e-76	263
rs:WP_027852468	DNA topoisomerase III [Marinobacterium litorale].	37.62	404	233	6	36	436	251	638	2e-76	263
rs:WP_011573665	DNA topoisomerase III [Pseudoalteromonas atlantica].	39.88	341	204	1	36	376	254	593	2e-76	263
rs:WP_000088631	DNA topoisomerase III [Vibrio sp. RC586].	39.14	350	206	1	36	385	255	597	2e-76	263
rs:WP_026083050	DNA topoisomerase III [Pseudomonas tolaasii].	37.92	385	231	3	36	414	241	623	2e-76	263
rs:WP_041023653	DNA topoisomerase III [Pseudomonas sp. SHC52].	37.20	379	235	2	31	408	236	612	2e-76	263
rs:WP_005523705	DNA topoisomerase III [Vibrio mimicus].	37.10	372	227	1	36	407	255	619	2e-76	263
rs:WP_038901156	DNA topoisomerase III [Dickeya dadantii].	37.60	375	225	4	36	409	251	617	2e-76	263
rs:WP_002440314	DNA topoisomerase III [Shimwellia blattae].	38.38	370	220	3	36	405	251	612	2e-76	263
tr:J2MLI7_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	39.48	347	208	1	61	407	270	614	2e-76	263
rs:WP_042054821	DNA topoisomerase III [Aeromonas veronii].	39.43	350	206	1	36	385	249	592	2e-76	263
rs:WP_016535970	DNA topoisomerase III [Cedecea davisae].	39.43	350	204	3	36	385	251	592	2e-76	263
tr:D2YDR8_VIBMI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.10	372	227	1	36	407	261	625	2e-76	263
rs:WP_020454016	DNA topoisomerase III [Enterobacter sp. R4-368].	37.19	398	241	4	36	433	251	639	2e-76	263
rs:WP_033746697	DNA topoisomerase III [Pantoea sp. NGS-ED-1003].	39.71	350	203	3	36	385	251	592	2e-76	263
rs:WP_048494155	DNA topoisomerase III [Marinobacter sp. JG233].	35.36	427	269	3	28	454	246	665	2e-76	265
rs:WP_006119409	DNA topoisomerase III [Pantoea stewartii].	39.71	350	203	3	36	385	251	592	2e-76	263
rs:WP_029887822	DNA topoisomerase III [Pseudomonas putida].	38.93	375	224	3	36	408	241	612	2e-76	263
rs:WP_046098044	DNA topoisomerase III [Avibacterium paragallinarum].	38.57	350	208	2	36	385	253	595	2e-76	263
rs:WP_017346306	DNA topoisomerase III [Pantoea sp. A4].	38.46	364	216	3	36	399	251	606	2e-76	263
rs:WP_007105160	DNA topoisomerase III [Paraglaciecola polaris].	39.43	350	203	1	36	385	256	596	2e-76	263
rs:WP_035385321	DNA topoisomerase III, partial [Ferrimonas futtsuensis].	38.75	351	208	2	35	385	250	593	2e-76	262
rs:WP_042082863	DNA topoisomerase III [Aeromonas veronii].	39.71	350	205	1	36	385	249	592	2e-76	263
rs:WP_036796284	DNA topoisomerase III, partial [Photobacterium phosphoreum].	39.84	364	209	4	36	396	146	502	2e-76	260
rs:WP_042705047	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	39.48	347	208	1	61	407	267	611	2e-76	263
rs:WP_021510069	DNA topoisomerase III [Pantoea dispersa].	40.46	351	199	4	36	385	251	592	2e-76	263
rs:WP_046385324	DNA topoisomerase III [Pseudomonas veronii].	37.97	374	229	2	36	408	241	612	2e-76	263
rs:WP_032989883	DNA topoisomerase III [Cronobacter sakazakii].	39.71	350	203	3	36	385	251	592	2e-76	263
rs:WP_022960734	DNA topoisomerase III [Pseudomonas pelagia].	34.52	423	265	5	33	454	238	649	2e-76	263
rs:WP_012723395	DNA topoisomerase III [Pseudomonas fluorescens].	39.08	348	210	1	61	408	267	612	2e-76	263
tr:B7LQ29_ESCF3	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.86	350	206	3	36	385	260	601	2e-76	263
rs:WP_044816425	DNA topoisomerase III, partial [Escherichia coli].	38.57	350	207	3	36	385	159	500	2e-76	261
rs:WP_019807124	DNA topoisomerase III [Osedax symbiont Rs1].	37.99	379	229	1	36	414	251	623	2e-76	263
rs:WP_034951167	DNA topoisomerase III, partial [Erwinia oleae].	42.27	343	187	5	108	450	1	332	2e-76	254
rs:WP_015834119	DNA topoisomerase III [Photorhabdus asymbiotica].	38.32	368	211	4	36	399	251	606	2e-76	263
rs:WP_001235777	DNA topoisomerase III [Shigella sonnei].	38.86	350	206	3	36	385	251	592	2e-76	263
rs:WP_026140036	DNA topoisomerase III [Pseudomonas veronii].	37.97	374	229	2	36	408	241	612	2e-76	263
rs:WP_047041314	DNA topoisomerase III [Enterobacter aerogenes].	38.86	350	206	3	36	385	251	592	2e-76	263
rs:WP_017411783	DNA topoisomerase III [Aeromonas salmonicida].	40.29	350	203	1	36	385	249	592	2e-76	263
rs:WP_043302582	DNA topoisomerase III [Pseudomonas sp. GM55].	38.90	347	210	1	61	407	270	614	2e-76	263
rs:WP_046614845	DNA topoisomerase III [Pseudomonas putida].	40.00	355	209	2	56	408	260	612	2e-76	263
rs:WP_001235831	DNA topoisomerase III [Escherichia coli].	38.86	350	206	3	36	385	251	592	2e-76	263
rs:WP_005514989	DNA topoisomerase III [Vibrio mimicus].	36.83	372	228	1	36	407	255	619	2e-76	263
rs:WP_047656004	DNA topoisomerase III, partial [Salmonella enterica].	38.86	350	206	3	36	385	251	592	2e-76	262
rs:WP_017027834	DNA topoisomerase III [Vibrio breoganii].	37.13	369	228	2	36	404	255	619	2e-76	263
rs:WP_023211957	DNA topoisomerase III [Salmonella enterica].	38.86	350	206	3	36	385	251	592	2e-76	263
rs:WP_038396119	DNA topoisomerase III [Salmonella enterica].	38.86	350	206	3	36	385	251	592	2e-76	263
rs:WP_001235834	DNA topoisomerase III [Shigella sonnei].	38.86	350	206	3	36	385	251	592	2e-76	263
rs:WP_047771906	DNA topoisomerase III [Xenorhabdus griffiniae].	39.06	361	203	5	36	391	251	599	2e-76	263
rs:WP_016781518	DNA topoisomerase III [Pseudomonas fragi].	37.11	380	234	2	61	437	267	644	2e-76	263
rs:WP_040177890	DNA topoisomerase III, partial [Klebsiella pneumoniae].	39.03	351	204	4	36	385	95	436	2e-76	258
rs:WP_000088632	MULTISPECIES: DNA topoisomerase III [Vibrio].	37.10	372	227	1	36	407	255	619	2e-76	263
rs:WP_038925922	DNA topoisomerase III [Dickeya zeae].	36.91	382	232	4	36	417	251	623	2e-76	262
tr:A9MFG7_SALAR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.86	350	206	3	36	385	251	592	2e-76	263
rs:WP_046035969	DNA topoisomerase III [Pseudomonas fluorescens].	39.08	348	210	1	61	408	267	612	2e-76	263
rs:WP_019689274	DNA topoisomerase III [Pseudomonas fluorescens].	35.70	423	254	7	36	452	241	651	2e-76	263
rs:WP_001235829	DNA topoisomerase III [Escherichia coli].	38.86	350	206	3	36	385	251	592	2e-76	263
rs:WP_024618692	DNA topoisomerase III [Pseudomonas fluorescens].	35.92	412	245	4	31	436	236	634	2e-76	263
rs:WP_042554705	DNA topoisomerase III [Pseudomonas fulva].	37.43	374	231	2	36	408	241	612	2e-76	263
rs:WP_039302172	DNA topoisomerase III [Cedecea neteri].	37.67	369	222	3	36	404	251	611	2e-76	263
tr:A4N2M3_HAEIF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.94	369	221	2	36	404	173	533	2e-76	260
rs:WP_043050240	DNA topoisomerase III [Pseudomonas fluorescens].	37.43	374	231	2	36	408	241	612	2e-76	263
tr:D2YND5_VIBMI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.10	372	227	1	36	407	258	622	2e-76	263
rs:WP_010561672	DNA topoisomerase III [Pseudoalteromonas spongiae].	37.84	370	221	2	36	405	251	611	3e-76	262
rs:WP_042350292	DNA topoisomerase III, partial [Escherichia coli].	38.29	350	208	3	36	385	90	431	3e-76	258
tr:J2SQG3_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	38.90	347	210	1	61	407	267	611	3e-76	262
rs:WP_024673600	DNA topoisomerase III [Pseudomonas syringae].	37.17	382	237	2	36	416	241	620	3e-76	263
rs:WP_045855018	DNA topoisomerase III [Raoultella terrigena].	37.76	384	224	4	36	412	251	626	3e-76	262
rs:WP_021441660	DNA topoisomerase III [Pseudomonas sp. EGD-AK9].	35.75	428	258	6	36	459	241	655	3e-76	263
rs:WP_033741875	DNA topoisomerase III [Pantoea stewartii].	39.71	350	203	3	36	385	251	592	3e-76	262
rs:WP_001235795	DNA topoisomerase III [Escherichia coli].	38.86	350	206	3	36	385	251	592	3e-76	263
rs:WP_025214575	DNA topoisomerase III [Pseudomonas brassicacearum].	35.68	412	246	4	31	436	236	634	3e-76	262
rs:WP_042199330	DNA topoisomerase III, partial [Escherichia coli].	38.57	350	207	3	36	385	198	539	3e-76	261
rs:WP_001618284	DNA topoisomerase III [Salmonella enterica].	38.86	350	206	3	36	385	251	592	3e-76	262
rs:WP_046081472	DNA topoisomerase III [Escherichia fergusonii].	38.86	350	206	3	36	385	251	592	3e-76	262
rs:WP_042610999	DNA topoisomerase III [Haemophilus influenzae].	37.94	369	221	2	36	404	260	620	3e-76	262
rs:WP_001587134	DNA topoisomerase III [Escherichia coli].	38.86	350	206	3	36	385	251	592	3e-76	262
rs:WP_021110768	DNA topoisomerase III [[Haemophilus] parasuis].	38.86	350	206	2	36	385	252	593	3e-76	262
rs:WP_032303179	DNA topoisomerase III [Escherichia coli].	38.86	350	206	3	36	385	251	592	3e-76	262
tr:A0A0B7JB60_PHOPO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000313|EMBL:CEO38588.1};	39.84	364	209	4	36	396	158	514	3e-76	260
rs:WP_031612074	DNA topoisomerase III, partial [Salmonella enterica].	38.57	350	207	3	36	385	225	566	3e-76	261
rs:WP_038154391	DNA topoisomerase III [Trabulsiella guamensis].	39.71	350	203	3	36	385	251	592	3e-76	262
rs:WP_021116949	DNA topoisomerase III [[Haemophilus] parasuis].	38.86	350	206	2	36	385	252	593	3e-76	262
rs:WP_001556646	DNA topoisomerase III [Escherichia coli].	38.86	350	206	3	36	385	251	592	3e-76	262
rs:WP_028762193	DNA topoisomerase III [Shewanella colwelliana].	37.46	355	222	0	32	386	247	601	3e-76	263
rs:WP_012142005	DNA topoisomerase III [Shewanella sediminis].	35.87	407	249	3	32	427	247	652	3e-76	263
rs:WP_045127804	DNA topoisomerase III [Photobacterium angustum].	39.43	350	207	2	36	385	251	595	3e-76	263
rs:WP_005691383	DNA topoisomerase III [Haemophilus influenzae].	37.94	369	221	2	36	404	260	620	3e-76	262
rs:WP_020909946	DNA topoisomerase III [Haemophilus influenzae].	37.94	369	221	2	36	404	260	620	3e-76	262
rs:WP_027662357	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	3e-76	262
rs:WP_034875432	DNA topoisomerase III [Endozoicomonas montiporae].	36.68	379	236	3	32	407	247	624	3e-76	262
rs:WP_045363723	DNA topoisomerase III [Enterobacter aerogenes].	38.86	350	206	3	36	385	251	592	3e-76	262
rs:WP_029570080	DNA topoisomerase III [Pantoea ananatis].	40.00	350	202	3	36	385	251	592	3e-76	262
rs:WP_007524702	DNA topoisomerase III [Haemophilus sputorum].	38.70	354	205	3	36	387	252	595	3e-76	262
rs:WP_035493689	DNA topoisomerase III [[Haemophilus] parasuis].	38.86	350	206	2	36	385	252	593	3e-76	262
rs:WP_047079528	DNA topoisomerase III [Enterobacter aerogenes].	38.86	350	206	3	36	385	251	592	3e-76	262
rs:WP_017032445	DNA topoisomerase III [Vibrio breoganii].	37.67	369	223	3	36	404	255	616	3e-76	262
rs:WP_000088633	DNA topoisomerase III [Vibrio mimicus].	36.83	372	228	1	36	407	255	619	3e-76	262
rs:WP_010446576	DNA topoisomerase III [Pseudomonas fuscovaginae].	37.63	380	232	2	61	437	267	644	3e-76	262
rs:WP_045151977	DNA topoisomerase III [Photobacterium angustum].	39.43	350	207	2	36	385	251	595	3e-76	262
rs:WP_014593831	DNA topoisomerase III [Pantoea ananatis].	40.00	350	202	3	36	385	251	592	3e-76	262
rs:WP_042870424	DNA topoisomerase III [Dickeya sp. NCPPB 569].	37.02	389	233	5	22	409	240	617	4e-76	262
rs:WP_042892724	DNA topoisomerase III [Enterobacter aerogenes].	38.86	350	206	3	36	385	251	592	4e-76	262
rs:WP_005760640	DNA topoisomerase III [Pasteurella bettyae].	36.04	394	241	3	11	404	231	613	4e-76	262
rs:WP_021118176	DNA topoisomerase III [[Haemophilus] parasuis].	39.14	350	205	2	36	385	252	593	4e-76	262
rs:WP_004386618	DNA topoisomerase III, partial [Cronobacter sakazakii].	39.43	350	204	3	36	385	251	592	4e-76	261
rs:WP_045411298	DNA topoisomerase III [Enterobacter aerogenes].	38.86	350	206	3	36	385	251	592	4e-76	262
rs:WP_004101300	DNA topoisomerase III [Klebsiella oxytoca].	39.14	350	205	3	36	385	251	592	4e-76	262
rs:WP_008092883	DNA topoisomerase III, partial [Pseudomonas sp. GM84].	38.67	375	225	3	36	408	241	612	4e-76	262
rs:WP_045183922	DNA topoisomerase III [Pseudomonas sp. 5].	37.17	374	232	2	36	408	241	612	4e-76	262
rs:WP_033865488	DNA topoisomerase III [Escherichia coli].	39.71	350	203	5	36	385	251	592	4e-76	262
rs:WP_021112325	DNA topoisomerase III [[Haemophilus] parasuis].	38.86	350	206	2	36	385	252	593	4e-76	262
tr:A6W0F1_MARMS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	36.90	355	221	2	35	389	250	601	4e-76	263
rs:WP_015366158	DNA topoisomerase III [Enterobacter aerogenes].	38.86	350	206	3	36	385	251	592	4e-76	262
rs:WP_038908043	DNA topoisomerase III [Dickeya zeae].	36.91	382	232	4	36	417	251	623	4e-76	262
rs:WP_035525287	DNA topoisomerase III [[Haemophilus] parasuis].	39.14	350	205	2	36	385	252	593	4e-76	262
rs:WP_001235851	DNA topoisomerase III [Escherichia albertii].	39.14	350	205	3	36	385	251	592	4e-76	262
rs:WP_020078544	DNA topoisomerase III [Enterobacter aerogenes].	38.86	350	206	3	36	385	251	592	4e-76	262
rs:WP_032714745	DNA topoisomerase III [Enterobacter aerogenes].	38.86	350	206	3	36	385	251	592	4e-76	262
rs:WP_015705779	DNA topoisomerase III [Enterobacter aerogenes].	38.86	350	206	3	36	385	251	592	4e-76	262
rs:WP_024704803	DNA topoisomerase III, partial [Escherichia coli].	38.57	350	207	3	36	385	251	592	4e-76	261
rs:WP_023169111	DNA topoisomerase III, partial [Salmonella enterica].	38.57	350	207	3	36	385	215	556	4e-76	261
tr:A0A0A6ZS57_SHIDY	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.57	350	207	3	36	385	270	611	4e-76	261
tr:A0A0F2VH94_SALET	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KJT19659.1};	38.57	350	207	3	36	385	206	547	4e-76	261
rs:WP_038995774	DNA topoisomerase III [Pseudomonas putida].	36.21	406	251	3	36	435	241	644	4e-76	262
rs:WP_046976083	DNA topoisomerase III [Photorhabdus temperata].	37.94	369	219	4	35	402	250	609	4e-76	262
rs:WP_005646774	DNA topoisomerase III [Haemophilus haemolyticus].	37.94	369	221	2	36	404	260	620	4e-76	262
rs:WP_001669743	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	4e-76	262
rs:WP_014550410	DNA topoisomerase III [Haemophilus influenzae].	37.94	369	221	2	36	404	260	620	4e-76	262
rs:WP_032277657	DNA topoisomerase III, partial [Escherichia coli].	38.57	350	207	3	36	385	221	562	4e-76	261
rs:WP_043042072	DNA topoisomerase III [Pseudomonas fluorescens].	37.40	377	218	3	65	436	271	634	4e-76	262
rs:WP_012315261	DNA topoisomerase III [Pseudomonas putida].	37.70	374	230	2	36	408	241	612	4e-76	262
rs:WP_038859932	DNA topoisomerase III, partial [Cronobacter sakazakii].	38.21	369	220	3	36	404	251	611	4e-76	261
rs:WP_025328625	DNA topoisomerase III [Aeromonas hydrophila].	40.29	350	202	2	36	385	249	591	4e-76	262
rs:WP_032728100	DNA topoisomerase III [Klebsiella oxytoca].	38.86	350	206	3	36	385	251	592	4e-76	262
rs:WP_045720885	DNA topoisomerase III, partial [Salmonella enterica].	38.57	350	207	3	36	385	206	547	4e-76	261
rs:WP_021782144	MULTISPECIES: DNA topoisomerase III [Pseudomonas putida group].	38.40	375	226	3	36	408	241	612	4e-76	262
rs:WP_001235826	DNA topoisomerase III [Escherichia coli].	38.92	352	203	4	36	385	251	592	4e-76	262
rs:WP_041028603	DNA topoisomerase III, partial [Salmonella enterica].	38.68	349	206	3	36	384	251	591	4e-76	260
rs:WP_036849554	DNA topoisomerase III [Photorhabdus temperata].	38.21	369	218	4	35	402	250	609	4e-76	261
rs:WP_035470059	DNA topoisomerase III, partial [Gammaproteobacteria bacterium MFB021].	36.25	411	242	3	35	436	242	641	5e-76	262
rs:WP_044862052	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	5e-76	262
rs:WP_001235791	MULTISPECIES: DNA topoisomerase III [Escherichia].	38.86	350	206	3	36	385	251	592	5e-76	262
rs:WP_001235836	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	5e-76	262
rs:WP_022963028	DNA topoisomerase III [Pseudomonas pelagia].	35.98	428	257	6	36	459	241	655	5e-76	262
rs:WP_001235810	DNA topoisomerase III [Escherichia coli].	35.66	401	239	4	36	436	251	632	5e-76	261
rs:WP_033867744	DNA topoisomerase III, partial [Escherichia coli].	38.57	350	207	3	36	385	251	592	5e-76	261
rs:WP_019677543	DNA topoisomerase III [Rheinheimera perlucida].	38.89	378	224	2	36	408	251	626	5e-76	263
rs:WP_047880060	DNA topoisomerase III [Photobacterium aquae].	37.25	357	221	1	36	392	251	604	5e-76	262
rs:WP_004112307	DNA topoisomerase III [Klebsiella oxytoca].	38.86	350	206	3	36	385	251	592	5e-76	262
rs:WP_009355184	DNA topoisomerase III [Vibrio sp. RC341].	37.40	369	224	1	36	404	255	616	5e-76	261
rs:WP_001504346	DNA topoisomerase III [Escherichia coli].	38.86	350	206	3	36	385	251	592	5e-76	262
rs:WP_021549854	DNA topoisomerase III [Escherichia coli].	35.66	401	239	4	36	436	251	632	5e-76	261
rs:WP_039025772	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	5e-76	261
rs:WP_027912566	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	37.40	377	218	3	65	436	271	634	5e-76	261
rs:WP_033548758	DNA topoisomerase III [Escherichia coli].	37.27	381	224	4	36	409	251	623	5e-76	261
rs:WP_021325539	DNA topoisomerase III [Photorhabdus temperata].	37.94	369	219	4	35	402	250	609	5e-76	261
rs:WP_025238906	DNA topoisomerase III [Escherichia albertii].	39.14	350	205	3	36	385	251	592	5e-76	261
rs:WP_016498844	DNA topoisomerase III [Pseudomonas putida].	40.06	342	203	1	67	408	273	612	5e-76	261
rs:WP_001357807	DNA topoisomerase III [Escherichia coli].	35.66	401	239	4	36	436	251	632	6e-76	261
rs:WP_023481300	DNA topoisomerase III [Enterobacter cloacae].	38.60	399	234	7	36	433	251	639	6e-76	261
rs:WP_025235882	DNA topoisomerase III [Mannheimia varigena].	38.86	350	206	3	36	385	252	593	6e-76	261
rs:WP_001235798	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	6e-76	261
rs:WP_015701651	DNA topoisomerase III [Haemophilus influenzae].	37.67	369	222	2	36	404	260	620	6e-76	261
rs:WP_047459250	DNA topoisomerase III [Citrobacter koseri].	39.94	363	210	3	29	389	232	588	6e-76	261
rs:WP_001578461	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	6e-76	261
rs:WP_021535386	DNA topoisomerase III [Escherichia coli].	35.66	401	239	4	36	436	251	632	6e-76	261
rs:WP_001538825	DNA topoisomerase III [Escherichia coli].	35.66	401	239	4	36	436	251	632	6e-76	261
rs:WP_001702636	DNA topoisomerase 3 [Escherichia coli].	38.57	350	207	3	36	385	251	592	6e-76	261
rs:WP_003251239	DNA topoisomerase III [Pseudomonas putida].	38.40	375	226	3	36	408	241	612	6e-76	261
rs:WP_042859776	DNA topoisomerase III [Dickeya sp. NCPPB 3274].	37.33	375	226	4	36	409	251	617	6e-76	261
rs:WP_001235817	MULTISPECIES: DNA topoisomerase III [Shigella].	38.57	350	207	3	36	385	251	592	6e-76	261
rs:WP_017146088	DNA topoisomerase III [Klebsiella oxytoca].	38.86	350	206	3	36	385	251	592	6e-76	261
rs:WP_039517865	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	6e-76	261
gp:CP006955_1251	DNA topoisomerase 3 [Bibersteinia trehalosi USDA-ARS-USMARC-189]	37.13	369	224	2	36	404	192	552	6e-76	259
rs:WP_016808486	DNA topoisomerase III [Klebsiella oxytoca].	38.86	350	206	3	36	385	251	592	6e-76	261
rs:WP_033552723	DNA topoisomerase III [Escherichia coli].	35.66	401	239	4	36	436	251	632	6e-76	261
rs:WP_013317851	DNA topoisomerase III [Dickeya dadantii].	37.33	375	226	4	36	409	251	617	6e-76	261
tr:A4MY79_HAEIF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	37.67	369	222	2	36	404	85	445	6e-76	257
rs:WP_042003754	DNA topoisomerase III [Escherichia coli].	35.73	403	240	4	36	438	251	634	6e-76	261
rs:WP_001235815	DNA topoisomerase III [Shigella flexneri].	38.57	350	207	3	36	385	251	592	6e-76	261
rs:WP_005617548	DNA topoisomerase III [Pseudomonas avellanae].	37.40	377	231	2	40	416	249	620	6e-76	261
rs:WP_044470732	DNA topoisomerase III [Mannheimia sp. MG13].	35.53	394	243	3	11	404	231	613	6e-76	261
rs:WP_023329567	MULTISPECIES: DNA topoisomerase III [Klebsiella].	38.86	350	206	3	36	385	251	592	6e-76	261
gp:CP007344_1434	DNA topoisomerase III [Salmonella enterica subsp. enterica serovar Enteritidis str.]	38.57	350	207	3	36	385	251	592	6e-76	261
rs:WP_041013292	DNA topoisomerase III [Pseudomonas xanthomarina].	38.22	382	228	3	36	413	241	618	6e-76	261
rs:WP_038349224	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	6e-76	261
rs:WP_046942476	DNA topoisomerase III [Haemophilus haemolyticus].	37.67	369	222	2	36	404	260	620	6e-76	261
rs:WP_042782438	DNA topoisomerase III, partial [Salmonella enterica].	38.57	350	207	3	36	385	251	592	6e-76	261
rs:WP_024248223	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	6e-76	261
rs:WP_014729094	DNA topoisomerase III [Cronobacter sakazakii].	37.06	402	242	5	36	437	251	641	7e-76	261
rs:WP_024797455	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	7e-76	261
gp:CP007348_1716	DNA topoisomerase III [Salmonella enterica subsp. enterica serovar Enteritidis str.]	35.56	405	240	5	36	438	251	636	7e-76	261
rs:WP_033553586	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	7e-76	261
rs:WP_001235847	DNA topoisomerase III [Escherichia fergusonii].	38.57	350	207	3	36	385	251	592	7e-76	261
rs:WP_032205278	DNA topoisomerase III [Escherichia coli].	36.29	394	232	4	36	429	251	625	7e-76	261
rs:WP_001610217	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	7e-76	261
rs:WP_022645779	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	7e-76	261
rs:WP_038916231	DNA topoisomerase III [Dickeya zeae].	36.98	384	229	5	36	414	251	626	7e-76	261
rs:WP_017440991	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	7e-76	261
rs:WP_031755045	DNA topoisomerase III [Pseudomonas aeruginosa].	36.59	399	243	4	61	459	267	655	7e-76	262
rs:WP_005639112	DNA topoisomerase III [Haemophilus haemolyticus].	37.94	369	221	2	36	404	260	620	7e-76	261
rs:WP_046083510	DNA topoisomerase III [Escherichia fergusonii].	38.57	350	207	3	36	385	251	592	7e-76	261
rs:WP_010390952	DNA topoisomerase III [Pseudoalteromonas undina].	40.57	350	199	1	36	385	251	591	7e-76	261
rs:WP_024157020	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	7e-76	261
rs:WP_045393274	DNA topoisomerase III [Enterobacter aerogenes].	38.86	350	206	3	36	385	251	592	7e-76	261
rs:WP_046788273	DNA topoisomerase III [Pseudomonas putida].	37.97	374	229	2	36	408	241	612	7e-76	261
rs:WP_013692697	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	37.40	377	218	3	65	436	271	634	7e-76	261
rs:WP_046077495	DNA topoisomerase III [Escherichia fergusonii].	38.57	350	207	3	36	385	251	592	7e-76	261
rs:WP_001235785	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	7e-76	261
rs:WP_039473015	DNA topoisomerase III [Pectobacterium carotovorum].	36.54	405	237	6	36	438	251	637	7e-76	261
gp:CP007434_1573	DNA topoisomerase III [Salmonella enterica subsp. enterica serovar Enteritidis str.]	38.57	350	207	3	36	385	251	592	7e-76	261
rs:WP_003283902	DNA topoisomerase III [Pseudomonas stutzeri].	37.73	379	234	2	36	413	241	618	7e-76	261
rs:WP_001235786	DNA topoisomerase III [Shigella boydii].	38.57	350	207	3	36	385	251	592	7e-76	261
rs:WP_021034374	DNA topoisomerase III [Haemophilus influenzae].	37.67	369	222	2	36	404	260	620	7e-76	261
rs:WP_001235874	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	8e-76	261
rs:WP_001235873	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	8e-76	261
rs:WP_043762485	DNA topoisomerase III [Aeromonas taiwanensis].	39.14	350	207	1	36	385	249	592	8e-76	261
rs:WP_025217413	DNA topoisomerase III [Mannheimia varigena].	39.14	350	205	3	36	385	252	593	8e-76	261
rs:WP_001235879	DNA topoisomerase III, partial [Salmonella enterica].	38.57	350	207	3	36	385	265	606	8e-76	261
rs:WP_019029803	DNA topoisomerase III [Colwellia piezophila].	37.74	371	229	1	32	400	249	619	8e-76	261
rs:WP_025247771	DNA topoisomerase III [Mannheimia varigena].	39.14	350	205	3	36	385	252	593	8e-76	261
rs:WP_011272053	MULTISPECIES: DNA topoisomerase III [Haemophilus].	37.67	369	222	2	36	404	260	620	8e-76	261
rs:WP_032711859	DNA topoisomerase III [Enterobacter aerogenes].	38.57	350	207	3	36	385	251	592	8e-76	261
rs:WP_023213983	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	8e-76	261
rs:WP_007893951	DNA topoisomerase III [Cronobacter sakazakii].	39.43	350	204	3	36	385	251	592	8e-76	261
tr:K1YUA4_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	37.59	415	233	7	34	445	242	633	8e-76	264
rs:WP_032427309	DNA topoisomerase III, partial [Klebsiella pneumoniae].	39.03	351	204	4	36	385	156	497	8e-76	259
gp:CP007354_1499	DNA topoisomerase III [Salmonella enterica subsp. enterica serovar Enteritidis str.]	38.57	350	207	3	36	385	251	592	8e-76	261
rs:WP_003200140	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	37.40	377	218	3	65	436	271	634	8e-76	261
rs:WP_045721498	DNA topoisomerase III, partial [Salmonella enterica].	38.57	350	207	3	36	385	251	592	8e-76	261
rs:WP_032281001	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	8e-76	261
rs:WP_044804532	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	8e-76	261
rs:WP_021518430	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	8e-76	261
rs:WP_001235814	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	8e-76	261
rs:WP_021712669	DNA topoisomerase III [Vibrio ezurae].	36.76	370	228	2	35	404	254	617	8e-76	261
rs:WP_034173447	DNA topoisomerase III [Escherichia coli].	37.08	383	228	4	36	413	251	625	8e-76	261
rs:WP_000294907	DNA topoisomerase III, partial [Salmonella enterica].	38.29	350	208	3	36	385	100	441	8e-76	257
rs:WP_021530492	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	8e-76	261
rs:WP_035519301	DNA topoisomerase III [Haemophilus parasuis].	38.86	350	206	2	36	385	252	593	8e-76	261
rs:WP_021114992	DNA topoisomerase III [[Haemophilus] parasuis].	38.86	350	206	2	36	385	252	593	8e-76	261
rs:WP_032171379	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	8e-76	261
rs:WP_001235872	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	8e-76	261
rs:WP_016941287	DNA topoisomerase III [Dickeya zeae].	36.79	386	235	4	36	420	251	628	8e-76	261
rs:WP_001549282	DNA topoisomerase 3 [Escherichia coli].	38.57	350	207	3	36	385	251	592	8e-76	261
rs:WP_001235802	DNA topoisomerase III [Escherichia coli].	36.29	394	232	4	36	429	251	625	8e-76	261
rs:WP_006248941	DNA topoisomerase III [Mannheimia haemolytica].	39.14	350	205	3	36	385	252	593	8e-76	261
rs:WP_033557449	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	8e-76	261
rs:WP_001559227	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	8e-76	261
rs:WP_006252007	DNA topoisomerase III [Mannheimia haemolytica].	39.14	350	205	3	36	385	252	593	9e-76	261
rs:WP_001337807	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	9e-76	261
rs:WP_047036902	DNA topoisomerase III [Enterobacter aerogenes].	39.03	351	204	4	36	385	251	592	9e-76	261
rs:WP_032257590	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	9e-76	261
tr:F4V2S6_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.57	350	207	3	36	385	260	601	9e-76	261
rs:WP_047977913	DNA topoisomerase III [[Actinobacillus] muris].	39.14	350	205	2	36	385	252	593	9e-76	261
rs:WP_031622230	DNA topoisomerase III, partial [Salmonella enterica].	38.57	350	207	3	36	385	236	577	9e-76	261
rs:WP_001529235	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	9e-76	261
rs:WP_028447326	DNA topoisomerase III [Chitinimonas koreensis].	35.65	418	258	6	36	452	241	648	9e-76	261
rs:WP_021540324	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	9e-76	261
rs:WP_001235809	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	9e-76	261
tr:A0A070TKB5_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.57	350	207	3	36	385	249	590	9e-76	261
rs:WP_001235808	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	9e-76	261
rs:WP_001235805	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	9e-76	261
rs:WP_023194085	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	9e-76	261
rs:WP_033559292	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	9e-76	261
rs:WP_033869912	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	9e-76	261
rs:WP_001235807	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	9e-76	261
rs:WP_001515429	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	38.57	350	207	3	36	385	251	592	9e-76	261
rs:WP_021279340	DNA topoisomerase III [Mannheimia haemolytica].	39.14	350	205	3	36	385	252	593	9e-76	261
rs:WP_001235794	DNA topoisomerase III [Shigella dysenteriae].	38.57	350	207	3	36	385	251	592	9e-76	261
rs:WP_001235820	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	9e-76	261
tr:F4VG14_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.57	350	207	3	36	385	260	601	9e-76	261
rs:WP_018355342	DNA topoisomerase III [[Pasteurella] pneumotropica].	38.75	369	218	2	36	404	260	620	9e-76	261
rs:WP_024242534	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	9e-76	261
rs:WP_001235804	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	38.57	350	207	3	36	385	251	592	9e-76	261
rs:WP_042947452	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	9e-76	261
rs:WP_001235864	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	9e-76	261
rs:WP_041413492	DNA topoisomerase III, partial [Shewanella frigidimarina].	38.46	364	211	3	32	385	247	607	9e-76	261
rs:WP_004860845	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	39.43	350	204	3	36	385	251	592	9e-76	261
rs:WP_001235866	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	9e-76	261
rs:WP_001235863	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	9e-76	261
rs:WP_023182068	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	9e-76	261
rs:WP_021531349	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235806	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235868	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235867	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_040034471	DNA topoisomerase III [Haemophilus influenzae].	37.67	369	222	2	36	404	260	620	1e-75	261
rs:WP_046953220	DNA topoisomerase III [Haemophilus haemolyticus].	37.67	369	222	2	36	404	260	620	1e-75	261
rs:WP_023202067	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_044864258	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001602679	DNA topoisomerase III [Escherichia coli].	37.08	383	228	4	36	413	251	625	1e-75	261
tr:F4SKI5_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.57	350	207	3	36	385	260	601	1e-75	261
tr:Q084R2_SHEFN	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.46	364	211	3	32	385	247	607	1e-75	261
tr:A0A0F3BD96_SALET	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KJU08730.1};	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_021573593	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235855	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235778	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001332112	MULTISPECIES: DNA topoisomerase III [Escherichia].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235860	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_032353289	DNA topoisomerase III, partial [Escherichia coli].	38.64	352	204	4	36	385	251	592	1e-75	260
rs:WP_023898920	MULTISPECIES: DNA topoisomerase III [Cronobacter].	39.43	350	204	3	36	385	251	592	1e-75	261
tr:G5LA33_SALET	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_032201055	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235884	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235793	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_005634570	DNA topoisomerase III [Haemophilus haemolyticus].	37.67	369	222	2	36	404	260	620	1e-75	261
rs:WP_023230805	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001613225	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235843	DNA topoisomerase III [Shigella dysenteriae].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_032325498	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_015584599	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	38.21	369	220	3	36	404	251	611	1e-75	261
rs:WP_001235799	MULTISPECIES: DNA topoisomerase III [Shigella].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_011146773	DNA topoisomerase III [Photorhabdus luminescens].	38.21	369	218	4	35	402	250	609	1e-75	261
rs:WP_032238281	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_044811103	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001621484	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235871	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	1e-75	261
sp:TOP3_SALTY	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_032314111	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
tr:B7MVP0_ECO81	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.57	350	207	3	36	385	270	611	1e-75	261
rs:WP_001235775	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_020898703	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_023205568	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_031485737	DNA topoisomerase I [Desulfovibrio frigidus].	33.54	483	256	6	35	459	243	718	1e-75	262
rs:WP_033814661	DNA topoisomerase III [Escherichia coli].	39.03	351	204	4	36	385	251	592	1e-75	261
rs:WP_001592093	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_045042815	DNA topoisomerase III [Photobacterium kishitanii].	39.84	364	209	4	36	396	251	607	1e-75	261
rs:WP_039556869	DNA topoisomerase III [Pectobacterium carotovorum].	36.54	405	237	6	36	438	251	637	1e-75	261
rs:WP_001235825	DNA topoisomerase III [Escherichia coli].	38.64	352	204	4	36	385	251	592	1e-75	261
rs:WP_021552583	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_042083422	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_044696303	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001718384	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_024008877	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001363417	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
gp:CP002211_1957	DNA topoisomerase III [Escherichia coli str. 'clone D i2']	38.57	350	207	3	36	385	270	611	1e-75	261
gp:AE014075_2103	DNA topoisomerase III [Escherichia coli CFT073]	38.57	350	207	3	36	385	270	611	1e-75	261
rs:WP_001235878	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235877	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235845	MULTISPECIES: DNA topoisomerase III [Shigella].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_024209137	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001479370	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001468817	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_005626523	DNA topoisomerase III [Haemophilus haemolyticus].	37.67	369	222	2	36	404	260	620	1e-75	261
rs:WP_001235780	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_016236697	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235801	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_011045511	DNA topoisomerase III [Colwellia psychrerythraea].	37.47	371	230	1	32	400	249	619	1e-75	261
rs:WP_047054042	DNA topoisomerase III [Enterobacter aerogenes].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_046519398	DNA topoisomerase III [Rheinheimera sp. IITR-13].	39.89	356	209	3	22	374	232	585	1e-75	261
rs:WP_001405289	DNA topoisomerase 3 [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235803	DNA topoisomerase 3 [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_024173215	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_045177124	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_045044901	DNA topoisomerase III [Photobacterium kishitanii].	39.84	364	209	4	36	396	251	607	1e-75	261
rs:WP_005686905	DNA topoisomerase III [Haemophilus influenzae].	37.94	369	221	2	36	404	260	620	1e-75	261
rs:WP_001235862	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235861	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235811	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
tr:A0A090NLN2_SHIDY	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.57	350	207	3	36	385	270	611	1e-75	261
rs:WP_032256164	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_023154312	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235819	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_031565776	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_012602800	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	270	611	1e-75	261
rs:WP_042594782	DNA topoisomerase III [Haemophilus influenzae].	37.67	369	222	2	36	404	260	620	1e-75	261
rs:WP_024209312	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_012055035	DNA topoisomerase III [Haemophilus influenzae].	37.67	369	222	2	36	404	260	620	1e-75	261
rs:WP_023405646	DNA topoisomerase III [Vibrio halioticoli].	36.49	370	229	2	35	404	254	617	1e-75	261
rs:WP_017020022	DNA topoisomerase III [Aliivibrio fischeri].	37.40	369	227	2	36	404	268	632	1e-75	261
rs:WP_001235882	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	264	605	1e-75	261
rs:WP_005356359	DNA topoisomerase III [Aeromonas veronii].	39.14	350	207	1	36	385	249	592	1e-75	260
rs:WP_038988777	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_032214108	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_024239616	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_023247999	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	1e-75	261
tr:A9N283_SALPB	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.57	350	207	3	36	385	257	598	1e-75	261
rs:WP_001235779	DNA topoisomerase 3 [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_032224183	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001687610	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_044865123	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001698540	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235840	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
tr:M8T5X1_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.57	350	207	3	36	385	249	590	1e-75	261
tr:G5RGI2_SALET	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_039544674	DNA topoisomerase III [Pectobacterium carotovorum].	36.72	403	235	6	36	436	251	635	1e-75	260
rs:WP_026917064	DNA topoisomerase III [[Haemophilus] parasuis].	38.86	350	206	2	36	385	252	593	1e-75	260
rs:WP_033560856	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_016245359	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
sp:TOP3_ECOLI	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	38.57	350	207	3	36	385	251	592	1e-75	261
tr:Q57PY5_SALCH	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.57	350	207	3	36	385	270	611	1e-75	261
rs:WP_012139595	DNA topoisomerase III [Marinobacter lipolyticus].	36.65	442	265	7	13	454	234	660	1e-75	262
rs:WP_046339371	DNA topoisomerase III [Pasteurella multocida].	36.00	400	244	4	5	404	238	625	1e-75	261
rs:WP_015672564	DNA topoisomerase III [Serratia marcescens].	37.63	372	224	3	36	407	251	614	1e-75	260
rs:WP_038857389	DNA topoisomerase III [Cronobacter universalis].	39.43	350	204	3	36	385	251	592	1e-75	261
gp:CP000468_1639	DNA topoisomerase III [Escherichia coli APEC O1]	38.57	350	207	3	36	385	269	610	1e-75	261
rs:WP_038439372	DNA topoisomerase III [Haemophilus influenzae].	37.67	369	222	2	36	404	260	620	1e-75	261
rs:WP_001235822	DNA topoisomerase III [Escherichia coli].	38.64	352	204	4	36	385	251	592	1e-75	261
rs:WP_005662588	DNA topoisomerase III [Haemophilus influenzae].	37.67	369	222	2	36	404	260	620	1e-75	260
rs:WP_038999926	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235846	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235821	DNA topoisomerase III [Escherichia coli].	38.64	352	204	4	36	385	251	592	1e-75	261
rs:WP_032203321	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235839	DNA topoisomerase III [Escherichia coli].	38.86	350	206	3	36	385	251	592	1e-75	261
rs:WP_047643878	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235784	DNA topoisomerase III [Escherichia coli].	38.64	352	204	4	36	385	251	592	1e-75	261
rs:WP_001400432	DNA topoisomerase 3 [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_032181066	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_040659182	DNA topoisomerase III, partial [Neisseria bacilliformis].	38.71	372	216	5	36	396	197	567	1e-75	258
tr:W1XDJ4_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	38.64	352	204	4	36	385	251	592	1e-75	259
rs:WP_038340935	DNA topoisomerase 3 [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_003904754	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001592585	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_024224548	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_047644316	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_016240855	DNA topoisomerase III [Escherichia coli].	38.64	352	204	4	36	385	251	592	1e-75	261
rs:WP_011104028	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	38.48	356	217	1	61	416	267	620	1e-75	261
rs:WP_001373800	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_007950567	DNA topoisomerase III [Pseudomonas sp. GM25].	38.62	347	211	1	61	407	267	611	1e-75	260
tr:Q0T4X0_SHIF8	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.57	350	207	3	36	385	270	611	1e-75	261
rs:WP_001760094	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
gp:CP005384_686	DNA topoisomerase III [Haemophilus parasuis ZJ0906]	38.86	350	206	2	36	385	252	593	1e-75	260
rs:WP_032141851	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_001235838	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	261
rs:WP_032286490	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-75	260
rs:WP_001235859	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	1e-75	260
rs:WP_032323149	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_001235813	DNA topoisomerase III [Shigella flexneri].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_040000899	DNA topoisomerase III [Dickeya chrysanthemi].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_024617231	DNA topoisomerase III [Pseudomonas fluorescens].	34.36	422	261	6	36	454	241	649	2e-75	261
tr:R4NN51_CLOBO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	36.27	397	236	4	36	425	35	421	2e-75	258
rs:WP_003655601	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_032180754	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_039059888	DNA topoisomerase III [Shigella flexneri].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_025760919	DNA topoisomerase III [Shigella flexneri].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_001235844	DNA topoisomerase 3 [Shigella boydii].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_001743829	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_038366492	DNA topoisomerase III [Pseudomonas chlororaphis].	39.19	347	209	1	61	407	267	611	2e-75	260
rs:WP_032264420	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_001569929	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_044008984	DNA topoisomerase III [[Haemophilus] parasuis].	38.86	350	206	2	36	385	252	593	2e-75	260
rs:WP_001480500	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_001235796	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
tr:G5R128_SALSE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.57	350	207	3	36	385	251	592	2e-75	261
rs:WP_042601082	DNA topoisomerase III [Haemophilus influenzae].	37.67	369	222	2	36	404	260	620	2e-75	260
rs:WP_001235776	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_001235824	MULTISPECIES: DNA topoisomerase III [Escherichia].	38.64	352	204	4	36	385	251	592	2e-75	260
rs:WP_001552958	DNA topoisomerase III [Escherichia coli].	38.64	352	204	4	36	385	251	592	2e-75	260
tr:F4NFA1_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.57	350	207	3	36	385	270	611	2e-75	261
rs:WP_047662696	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_008568568	DNA topoisomerase III [Pseudomonas sp. Chol1].	37.98	387	237	2	23	408	231	615	2e-75	260
rs:WP_032162751	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_024169425	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_021574631	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_021542329	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
tr:A0A0E9BB58_PANAN	SubName: Full=DNA topoisomerase 3 (ECO:0000255|HAMAP-Rule:MF_00953) {ECO:0000313|EMBL:CRH29575.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRH29575.1};	40.00	350	202	3	36	385	251	592	2e-75	260
rs:WP_033885626	DNA topoisomerase 3 [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_001235823	DNA topoisomerase III [Escherichia coli].	38.64	352	204	4	36	385	251	592	2e-75	260
sp:TOP3_HAEIN	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	37.94	369	221	2	36	404	260	620	2e-75	260
rs:WP_046123363	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_044332759	DNA topoisomerase III [Haemophilus influenzae].	37.67	369	222	2	36	404	260	620	2e-75	260
rs:WP_001524791	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_033082620	DNA topoisomerase III [Colwellia psychrerythraea].	38.07	352	216	1	36	385	253	604	2e-75	260
rs:WP_025745153	DNA topoisomerase III [Shigella flexneri].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_021571873	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_001235816	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_008915794	DNA topoisomerase III [Providencia sneebia].	40.29	350	201	3	36	385	251	592	2e-75	260
rs:WP_001235827	MULTISPECIES: DNA topoisomerase III [Escherichia].	38.35	352	205	4	36	385	251	592	2e-75	260
rs:WP_025389477	DNA topoisomerase III [Pseudomonas syringae].	37.17	374	232	2	36	408	241	612	2e-75	260
rs:WP_043861109	DNA topoisomerase III [Pseudomonas putida].	38.40	375	224	2	67	436	273	645	2e-75	260
rs:WP_012602298	DNA topoisomerase III [Escherichia coli].	38.64	352	204	4	36	385	270	611	2e-75	261
rs:WP_001520656	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	38.64	352	204	4	36	385	251	592	2e-75	260
rs:WP_040078861	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_025163529	DNA topoisomerase III [Pseudomonas taeanensis].	38.03	355	213	2	65	414	271	623	2e-75	260
rs:WP_001235818	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_014448815	DNA topoisomerase III [Leptospirillum ferrooxidans].	34.97	449	251	11	28	459	260	684	2e-75	263
rs:WP_046950329	DNA topoisomerase III [Haemophilus haemolyticus].	37.67	369	222	2	36	404	260	620	2e-75	260
rs:WP_005656475	DNA topoisomerase III [Haemophilus influenzae].	37.67	369	222	2	36	404	260	620	2e-75	260
rs:WP_001235842	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_012769917	MULTISPECIES: DNA topoisomerase III [Dickeya].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_007249706	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	38.48	356	217	1	61	416	267	620	2e-75	260
rs:WP_039335056	hypothetical protein, partial [Burkholderia multivorans].	37.30	429	247	10	35	446	240	663	2e-75	261
rs:WP_001235828	DNA topoisomerase III [Escherichia sp. TW09231].	38.35	352	205	4	36	385	251	592	2e-75	260
rs:WP_015432516	DNA topoisomerase III [Bibersteinia trehalosi].	37.13	369	224	2	36	404	252	612	2e-75	259
rs:WP_036837072	DNA topoisomerase III [Photorhabdus temperata].	37.67	369	220	4	35	402	250	609	2e-75	260
rs:WP_032102106	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_001461041	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_039066058	DNA topoisomerase III [Shigella flexneri].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_023490164	DNA topoisomerase 3 [Serratia sp. DD3].	36.63	374	225	4	36	407	251	614	2e-75	260
rs:WP_033545713	DNA topoisomerase 3 [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_038625843	DNA topoisomerase III [Pantoea sp. PSNIH2].	39.01	364	214	3	36	399	251	606	2e-75	260
rs:WP_036774908	DNA topoisomerase III [Photorhabdus asymbiotica].	38.04	368	212	4	36	399	251	606	2e-75	260
rs:WP_023233854	DNA topoisomerase III [Salmonella enterica].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_040234617	DNA topoisomerase III [Shigella flexneri].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_001235833	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_033791181	DNA topoisomerase III [Pantoea sp. FF5].	39.89	351	201	4	36	385	251	592	2e-75	259
rs:WP_005659784	DNA topoisomerase III [Haemophilus influenzae].	37.67	369	222	2	36	404	260	620	2e-75	260
rs:WP_001235852	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	38.64	352	204	4	36	385	251	592	2e-75	260
rs:WP_009653400	MULTISPECIES: DNA topoisomerase III [Klebsiella].	39.03	351	204	4	36	385	251	592	2e-75	260
rs:WP_039602441	DNA topoisomerase III [Pseudomonas putida].	37.43	374	231	2	36	408	241	612	2e-75	260
rs:WP_001235832	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_038918989	DNA topoisomerase III [Dickeya sp. MK7].	37.33	375	226	4	36	409	251	617	2e-75	259
tr:L8U5T5_AGGAC	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.75	351	208	2	54	404	275	618	2e-75	260
rs:WP_032209748	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_001235781	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_024216553	DNA topoisomerase III [Escherichia coli].	38.64	352	204	4	36	385	251	592	2e-75	260
rs:WP_001235841	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_045196653	DNA topoisomerase III [Pseudomonas sp. 2(2015)].	38.24	374	224	2	67	435	273	644	2e-75	260
rs:WP_046893476	DNA topoisomerase III [Morganella morganii].	38.08	365	215	4	22	386	240	593	2e-75	260
rs:WP_013202431	DNA topoisomerase III [Erwinia billingiae].	39.71	350	203	3	36	385	251	592	2e-75	259
rs:WP_011334736	DNA topoisomerase III [Pseudomonas fluorescens].	38.62	347	211	1	61	407	267	611	2e-75	260
tr:W1GKG1_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.29	350	208	3	36	385	215	556	2e-75	259
rs:WP_044697366	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-75	260
rs:WP_001235876	DNA topoisomerase III [Salmonella enterica].	38.29	350	208	3	36	385	251	592	2e-75	260
rs:WP_013366590	DNA topoisomerase III [Enterobacter lignolyticus].	38.86	350	206	3	36	385	251	592	3e-75	259
rs:WP_027712141	DNA topoisomerase III [Dickeya chrysanthemi].	38.57	350	207	3	36	385	251	592	3e-75	259
rs:WP_004892848	DNA topoisomerase III [Klebsiella pneumoniae].	39.03	351	204	4	36	385	251	592	3e-75	260
rs:WP_019411547	DNA topoisomerase III [Pseudomonas psychrophila].	37.92	356	219	1	61	416	267	620	3e-75	259
rs:WP_004121401	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	39.03	351	204	4	36	385	251	592	3e-75	260
rs:WP_032417775	DNA topoisomerase III [Klebsiella pneumoniae].	39.03	351	204	4	36	385	251	592	3e-75	259
rs:WP_002901390	MULTISPECIES: DNA topoisomerase III [Klebsiella].	39.03	351	204	4	36	385	251	592	3e-75	259
rs:WP_041145117	DNA topoisomerase III [Raoultella ornithinolytica].	39.14	350	205	3	36	385	251	592	3e-75	260
rs:WP_045184773	DNA topoisomerase III [Photobacterium angustum].	39.14	350	208	2	36	385	251	595	3e-75	260
rs:WP_001235875	DNA topoisomerase III [Salmonella enterica].	38.29	350	208	3	36	385	251	592	3e-75	259
rs:WP_005699835	DNA topoisomerase III [Haemophilus parainfluenzae].	35.66	401	236	3	36	436	256	634	3e-75	259
rs:WP_007246696	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	38.48	356	217	1	61	416	267	620	3e-75	260
rs:WP_004225438	DNA topoisomerase III [Klebsiella pneumoniae].	39.03	351	204	4	36	385	251	592	3e-75	259
tr:Q2BXW9_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	38.86	350	209	1	36	385	154	498	3e-75	258
rs:WP_021806609	DNA topoisomerase III [Serratia fonticola].	37.10	372	226	3	36	407	251	614	3e-75	259
tr:A0A078LIC9_CITKO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	39.03	351	204	4	36	385	251	592	3e-75	259
rs:WP_021523123	DNA topoisomerase III [Escherichia coli].	38.64	352	204	4	36	385	251	592	3e-75	259
rs:WP_020244836	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	3e-75	259
rs:WP_040084318	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	3e-75	259
rs:WP_032414799	DNA topoisomerase III [Klebsiella pneumoniae].	39.03	351	204	4	36	385	251	592	3e-75	259
rs:WP_001626260	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	3e-75	259
rs:WP_013526469	DNA topoisomerase III [Haemophilus influenzae].	35.87	407	247	4	1	404	225	620	3e-75	259
rs:WP_013972307	DNA topoisomerase III [Pseudomonas putida].	37.91	430	246	6	29	454	234	646	3e-75	260
rs:WP_039847764	DNA topoisomerase III, partial [Haemophilus pittmaniae].	37.67	369	222	2	36	404	256	616	3e-75	259
rs:WP_024968239	DNA topoisomerase III [Pantoea sp. IMH].	39.02	387	220	6	36	414	251	629	3e-75	259
rs:WP_007678182	DNA topoisomerase III [Cronobacter condimenti].	39.43	350	204	3	36	385	251	592	3e-75	259
rs:WP_001235787	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	3e-75	259
rs:WP_003180391	DNA topoisomerase III [Pseudomonas fluorescens].	36.47	414	240	6	31	436	236	634	3e-75	259
gp:AP006725_567	putative DNA topoisomerase [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]	39.12	363	213	3	29	389	187	543	3e-75	257
tr:F3GC87_PSESJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	39.34	366	210	4	88	452	1	355	3e-75	252
rs:WP_036408089	DNA topoisomerase III [Morganella morganii].	38.36	365	214	4	22	386	240	593	3e-75	259
rs:WP_032749499	DNA topoisomerase III [Klebsiella oxytoca].	39.03	351	204	4	36	385	251	592	3e-75	259
tr:F9Q6Z6_9PAST	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.67	369	222	2	36	404	256	616	3e-75	259
rs:WP_044421241	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	37.92	356	219	1	61	416	267	620	3e-75	260
rs:WP_044204558	DNA topoisomerase III [Pectobacterium carotovorum].	36.30	405	238	6	36	438	251	637	3e-75	259
rs:WP_039489549	DNA topoisomerase III [Pectobacterium carotovorum].	36.30	405	238	6	36	438	251	637	3e-75	259
rs:WP_001235881	DNA topoisomerase III [Salmonella enterica].	38.29	350	208	3	36	385	251	592	3e-75	259
rs:WP_045148393	DNA topoisomerase III [Photobacterium angustum].	39.14	350	208	2	36	385	251	595	3e-75	259
rs:WP_001235789	DNA topoisomerase 3 [Escherichia coli].	38.29	350	208	3	36	385	251	592	3e-75	259
rs:WP_001235797	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	3e-75	259
rs:WP_001235782	DNA topoisomerase III [Escherichia sp. TW14182].	38.35	352	205	4	36	385	251	592	3e-75	259
rs:WP_005712905	DNA topoisomerase III [[Haemophilus] parasuis].	38.86	350	206	2	36	385	252	593	3e-75	259
rs:WP_005738886	DNA topoisomerase III [Pseudomonas amygdali].	38.15	346	214	0	61	406	267	612	3e-75	260
rs:WP_035604935	DNA topoisomerase III [Edwardsiella tarda].	39.71	350	203	3	36	385	251	592	3e-75	259
rs:WP_032695843	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	39.14	350	205	3	36	385	251	592	4e-75	259
tr:X0NXT2_PHOLE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	38.46	364	216	3	36	396	139	497	4e-75	257
rs:WP_024656059	DNA topoisomerase III [Pseudomonas syringae].	37.60	375	225	3	36	406	241	610	4e-75	259
rs:WP_023216208	DNA topoisomerase III [Salmonella enterica].	38.29	350	208	3	36	385	251	592	4e-75	259
rs:WP_021550670	DNA topoisomerase III [Escherichia coli].	38.35	352	205	4	36	385	251	592	4e-75	259
rs:WP_032688194	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	39.14	350	205	3	36	385	251	592	4e-75	259
rs:WP_042203675	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	4e-75	259
rs:WP_024647114	DNA topoisomerase III [Pseudomonas syringae].	38.68	349	212	1	60	408	266	612	4e-75	259
rs:WP_032428827	DNA topoisomerase III [Klebsiella pneumoniae].	38.92	352	203	4	36	385	251	592	4e-75	259
rs:WP_025342567	DNA topoisomerase III [Mannheimia varigena].	38.86	350	206	3	36	385	252	593	4e-75	259
rs:WP_007966854	DNA topoisomerase III [Pseudomonas sp. GM30].	38.33	347	212	1	61	407	267	611	4e-75	259
rs:WP_032358600	DNA topoisomerase 3 [Escherichia coli].	38.29	350	208	3	36	385	251	592	4e-75	259
rs:WP_032225326	DNA topoisomerase III [Escherichia coli].	38.35	352	205	4	36	385	251	592	4e-75	259
rs:WP_001403074	DNA topoisomerase 3 [Escherichia coli].	38.29	350	208	3	36	385	251	592	4e-75	259
rs:WP_027611731	DNA topoisomerase III [Pseudomonas sp. URIL14HWK12:I6].	38.62	347	211	1	61	407	267	611	4e-75	259
rs:WP_034944768	DNA topoisomerase III [Erwinia oleae].	38.90	365	215	3	36	400	251	607	4e-75	259
rs:WP_033569999	DNA topoisomerase III [Dickeya sp. 2B12].	37.33	375	226	4	36	409	251	617	4e-75	259
rs:WP_043291748	hypothetical protein, partial [Burkholderia vietnamiensis].	38.07	373	225	1	35	401	251	623	4e-75	259
rs:WP_032207849	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	4e-75	259
rs:WP_024249166	DNA topoisomerase III [Shigella sonnei].	38.29	350	208	3	36	385	251	592	4e-75	259
rs:WP_047627332	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	4e-75	259
rs:WP_010295239	DNA topoisomerase III [Pectobacterium carotovorum].	36.30	405	238	6	36	438	251	637	4e-75	259
rs:WP_039315128	DNA topoisomerase III [Pectobacterium carotovorum].	36.30	405	238	6	36	438	251	637	4e-75	259
rs:WP_014228966	MULTISPECIES: DNA topoisomerase III [Klebsiella].	39.03	351	204	4	36	385	251	592	4e-75	259
rs:WP_005285122	DNA topoisomerase III [Edwardsiella tarda].	39.71	350	203	3	36	385	251	592	4e-75	259
rs:WP_034915212	DNA topoisomerase III [Erwinia sp. 9145].	37.06	402	234	4	36	437	251	633	4e-75	259
rs:WP_001468051	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	4e-75	259
rs:WP_008950433	DNA topoisomerase III [Alishewanella jeotgali].	39.03	351	213	1	36	385	251	601	4e-75	259
rs:WP_043128703	DNA topoisomerase III, partial [Photobacterium leiognathi].	38.46	364	216	3	36	396	150	508	4e-75	257
rs:WP_020231706	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	4e-75	259
rs:WP_042165951	DNA topoisomerase III [Pseudomonas aeruginosa].	34.91	444	263	7	31	459	236	668	4e-75	261
rs:WP_001674355	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	4e-75	259
rs:WP_001544610	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	4e-75	259
rs:WP_016158144	MULTISPECIES: DNA topoisomerase III [Escherichia].	38.35	352	205	4	36	385	251	592	4e-75	259
rs:WP_042024539	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	4e-75	259
rs:WP_038914000	DNA topoisomerase III [Dickeya zeae].	36.98	384	229	5	36	414	251	626	4e-75	259
rs:WP_047684630	DNA topoisomerase III [Klebsiella oxytoca].	39.03	351	204	4	36	385	251	592	4e-75	259
rs:WP_048261807	DNA topoisomerase III [Klebsiella oxytoca].	39.03	351	204	4	36	385	251	592	4e-75	259
rs:WP_039514922	DNA topoisomerase III [Pectobacterium carotovorum].	36.30	405	238	6	36	438	251	637	4e-75	259
rs:WP_005698708	MULTISPECIES: DNA topoisomerase III [Haemophilus].	35.66	401	236	3	36	436	256	634	5e-75	259
rs:WP_045035773	DNA topoisomerase III [Photobacterium iliopiscarium].	39.56	364	210	4	36	396	251	607	5e-75	259
rs:WP_001600005	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	5e-75	259
rs:WP_001235790	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	5e-75	259
rs:WP_025210557	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	5e-75	259
rs:WP_039310032	DNA topoisomerase III, partial [Clostridium botulinum].	36.27	397	236	4	36	425	127	513	5e-75	258
rs:WP_040032912	DNA topoisomerase III [Pectobacterium carotovorum].	36.30	405	238	6	36	438	251	637	5e-75	259
rs:WP_039693940	DNA topoisomerase III [Dickeya solani].	37.07	375	227	4	36	409	251	617	5e-75	259
rs:WP_014576643	DNA topoisomerase III [Marinobacter adhaerens].	33.96	480	254	8	32	459	250	718	5e-75	261
rs:WP_036108821	DNA topoisomerase III, partial [Mangrovibacter sp. MFB070].	38.59	368	214	4	36	401	251	608	5e-75	259
rs:WP_025757480	DNA topoisomerase III [Shigella flexneri].	38.57	350	207	3	36	385	251	592	5e-75	259
rs:WP_025121009	MULTISPECIES: DNA topoisomerase III [Serratia].	37.70	374	221	5	36	407	251	614	5e-75	259
rs:WP_048289229	DNA topoisomerase III [Klebsiella pneumoniae].	39.03	351	204	4	36	385	251	592	5e-75	259
rs:WP_022989658	DNA topoisomerase III [Marinobacter sp. ES-1].	33.97	471	261	6	32	459	250	713	5e-75	261
rs:WP_027592745	DNA topoisomerase III [Pseudomonas sp. LAIL14HWK12:I7].	38.87	373	223	3	36	406	241	610	5e-75	259
rs:WP_048351566	DNA topoisomerase III [Pseudomonas psychrophila].	38.15	346	212	1	61	406	267	610	5e-75	259
rs:WP_010275359	DNA topoisomerase III [Pectobacterium carotovorum].	36.30	405	238	6	36	438	251	637	5e-75	259
tr:A0A071LW77_9ENTR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.59	368	214	4	36	401	251	608	5e-75	259
rs:WP_047597620	DNA topoisomerase III [Pseudomonas sp. RIT288].	38.33	347	212	1	61	407	267	611	5e-75	259
rs:WP_036805538	DNA topoisomerase III [Photorhabdus luminescens].	37.67	369	220	4	35	402	250	609	5e-75	259
rs:WP_011961680	DNA topoisomerase III [Haemophilus influenzae].	37.67	369	222	2	36	404	260	620	5e-75	259
rs:WP_036780803	DNA topoisomerase III [Photorhabdus luminescens].	37.67	369	220	4	35	402	250	609	5e-75	259
rs:WP_005771280	DNA topoisomerase III [Pseudomonas amygdali].	38.48	356	217	1	61	416	267	620	5e-75	259
rs:WP_042938256	DNA topoisomerase III [Klebsiella pneumoniae].	39.03	351	204	4	36	385	251	592	5e-75	259
rs:WP_004183670	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	39.03	351	204	4	36	385	251	592	5e-75	259
rs:WP_024229705	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	5e-75	259
rs:WP_014870525	DNA topoisomerase III [Marinobacter sp. BSs20148].	34.80	477	251	7	32	459	250	715	6e-75	260
rs:WP_025289344	DNA topoisomerase III [Bibersteinia trehalosi].	36.86	369	225	2	36	404	252	612	6e-75	258
rs:WP_019828878	DNA topoisomerase III [Pseudomonas sp. CF149].	38.15	346	212	1	61	406	267	610	6e-75	259
rs:WP_023282373	DNA topoisomerase III [Klebsiella pneumoniae].	39.03	351	204	4	36	385	251	592	6e-75	259
rs:WP_023279896	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	39.03	351	204	4	36	385	251	592	6e-75	259
rs:WP_019705495	DNA topoisomerase III [Klebsiella pneumoniae].	39.03	351	204	4	36	385	251	592	6e-75	259
rs:WP_032438565	DNA topoisomerase III [Klebsiella pneumoniae].	39.03	351	204	4	36	385	251	592	6e-75	259
rs:WP_046809689	DNA topoisomerase III [Pseudomonas psychrophila].	38.15	346	212	1	61	406	267	610	6e-75	259
rs:WP_041981894	DNA topoisomerase III [Xenorhabdus nematophila].	34.61	445	269	5	18	450	213	647	6e-75	259
rs:WP_009486072	MULTISPECIES: DNA topoisomerase III [Klebsiella].	39.03	351	204	4	36	385	251	592	6e-75	259
rs:WP_040174316	DNA topoisomerase III [Klebsiella pneumoniae].	39.03	351	204	4	36	385	251	592	6e-75	259
rs:WP_028241262	DNA topoisomerase III [Pseudomonas azotifigens].	37.63	388	237	3	23	408	228	612	6e-75	259
rs:WP_004850046	DNA topoisomerase III [Klebsiella oxytoca].	38.75	351	205	4	36	385	251	592	6e-75	259
rs:WP_019845046	DNA topoisomerase III [Dickeya zeae].	36.98	384	229	5	36	414	251	626	6e-75	259
rs:WP_045146800	DNA topoisomerase III [Escherichia coli].	38.35	352	205	4	36	385	251	592	6e-75	259
rs:WP_004148065	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	39.03	351	204	4	36	385	251	592	6e-75	259
rs:WP_023283560	DNA topoisomerase III [Klebsiella pneumoniae].	39.03	351	204	4	36	385	251	592	6e-75	259
rs:WP_032179590	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	6e-75	259
rs:WP_032419855	DNA topoisomerase III [Klebsiella pneumoniae].	39.03	351	204	4	36	385	251	592	6e-75	259
rs:WP_038807864	DNA topoisomerase III [Klebsiella pneumoniae].	39.03	351	204	4	36	385	251	592	6e-75	259
rs:WP_012905567	DNA topoisomerase III [Citrobacter rodentium].	38.57	350	207	3	36	385	251	592	6e-75	259
rs:WP_027977778	DNA topoisomerase III [gamma proteobacterium L18].	36.90	374	233	2	36	408	241	612	6e-75	259
rs:WP_034494731	DNA topoisomerase III [Buttiauxella agrestis].	37.47	379	229	3	36	414	251	621	6e-75	259
rs:WP_005762746	DNA topoisomerase III [Pasteurella dagmatis].	35.16	401	246	6	5	404	238	625	6e-75	259
rs:WP_001537001	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	6e-75	259
rs:WP_031589874	DNA topoisomerase III [Klebsiella pneumoniae].	39.03	351	204	4	36	385	251	592	6e-75	259
tr:A0A0E9ZU39_9PSED	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KIY42383.1};	39.77	352	208	2	59	408	263	612	7e-75	259
rs:WP_032290511	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	7e-75	259
rs:WP_039020743	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	7e-75	259
rs:WP_004203795	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	39.03	351	204	4	36	385	251	592	7e-75	258
rs:WP_039611528	DNA topoisomerase III [Pseudoalteromonas luteoviolacea].	37.39	353	214	1	33	385	248	593	7e-75	258
rs:WP_007760307	DNA topoisomerase III [Siccibacter turicensis].	39.14	350	205	3	36	385	251	592	7e-75	259
tr:F4SYZ0_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.29	350	208	3	36	385	260	601	7e-75	259
rs:WP_039804356	DNA topoisomerase III [Azotobacter chroococcum].	36.93	398	243	3	23	414	231	626	7e-75	259
rs:WP_032431711	DNA topoisomerase III [Klebsiella pneumoniae].	39.03	351	204	4	36	385	251	592	7e-75	259
rs:WP_032492626	DNA topoisomerase III [Pseudomonas putida].	35.70	423	255	6	36	454	241	650	7e-75	259
rs:WP_039464120	DNA topoisomerase III [Pectobacterium carotovorum].	36.48	403	236	6	36	436	251	635	7e-75	258
rs:WP_032153052	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	7e-75	259
rs:WP_031480058	DNA topoisomerase I [Desulfovibrio frigidus].	33.13	483	258	7	35	459	243	718	7e-75	260
rs:WP_025111358	DNA topoisomerase III [Pseudomonas sp. H1h].	38.33	347	212	1	61	407	267	611	7e-75	258
rs:WP_014915327	DNA topoisomerase III [Pectobacterium carotovorum].	36.48	403	236	6	36	436	251	635	7e-75	258
rs:WP_001235830	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	38.29	350	208	3	36	385	251	592	7e-75	259
rs:WP_025714542	DNA topoisomerase III [Klebsiella sp. 10982].	38.75	351	205	4	36	385	251	592	7e-75	258
rs:WP_023339139	DNA topoisomerase III [Klebsiella pneumoniae].	39.03	351	204	4	36	385	251	592	7e-75	258
tr:A0A0A8LKP9_XENNE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.61	445	269	5	18	450	219	653	7e-75	259
rs:WP_010128333	DNA topoisomerase III [Haemophilus sputorum].	38.42	354	206	3	36	387	252	595	7e-75	258
rs:WP_001519770	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	7e-75	259
rs:WP_040552170	DNA topoisomerase III, partial [Rheinheimera nanhaiensis].	38.06	360	213	1	36	385	256	615	8e-75	258
rs:WP_039554976	DNA topoisomerase III [Pectobacterium carotovorum].	36.48	403	236	6	36	436	251	635	8e-75	258
rs:WP_005641248	DNA topoisomerase III [Haemophilus haemolyticus].	37.40	369	223	2	36	404	260	620	8e-75	258
rs:WP_039529009	DNA topoisomerase III [Pectobacterium carotovorum].	36.48	403	236	6	36	436	251	635	8e-75	258
rs:WP_040226472	DNA topoisomerase III [Klebsiella pneumoniae].	39.03	351	204	4	36	385	251	592	8e-75	258
rs:WP_039881886	DNA topoisomerase III [Marinobacter manganoxydans].	33.47	484	259	8	28	459	246	718	8e-75	260
rs:WP_020585005	DNA topoisomerase III [Endozoicomonas elysicola].	36.68	379	237	3	32	408	247	624	8e-75	258
rs:WP_023397678	DNA topoisomerase III [Pseudoalteromonas luteoviolacea].	36.21	406	244	4	35	438	250	642	8e-75	258
rs:WP_023318003	DNA topoisomerase III [Klebsiella pneumoniae].	39.03	351	204	4	36	385	251	592	8e-75	258
rs:WP_042732096	DNA topoisomerase III [Pseudomonas fluorescens].	36.94	379	236	2	31	408	236	612	8e-75	258
rs:WP_017709126	DNA topoisomerase III [Pseudomonas syringae].	38.73	346	210	1	61	406	267	610	9e-75	259
rs:WP_032092263	DNA topoisomerase III [Necropsobacter rosorum].	37.80	381	227	3	36	414	253	625	9e-75	258
rs:WP_016234421	DNA topoisomerase III [Escherichia coli].	38.64	352	204	4	36	385	251	592	9e-75	258
rs:WP_023581968	DNA topoisomerase III [Proteus hauseri].	38.19	364	217	3	36	399	251	606	9e-75	258
rs:WP_021181214	DNA topoisomerase III [Serratia fonticola].	37.10	372	226	3	36	407	251	614	9e-75	258
rs:WP_005696836	DNA topoisomerase III [Haemophilus parainfluenzae].	35.66	401	236	3	36	436	256	634	9e-75	258
rs:WP_001688676	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	9e-75	258
rs:WP_001696283	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	9e-75	258
rs:WP_039511341	DNA topoisomerase III [Pectobacterium carotovorum].	36.48	403	236	6	36	436	251	635	9e-75	258
rs:WP_023289280	MULTISPECIES: DNA topoisomerase III [Klebsiella].	39.03	351	204	4	36	385	251	592	9e-75	258
rs:WP_036979860	DNA topoisomerase III [Pseudoalteromonas sp. SCSIO_11900].	39.30	374	215	2	36	406	251	615	9e-75	258
rs:WP_042060564	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	9e-75	258
rs:WP_036191270	DNA topoisomerase III [Marinobacterium sp. AK27].	39.49	352	201	2	36	386	251	591	9e-75	259
rs:WP_038391157	DNA topoisomerase III [Salmonella bongori].	38.00	350	209	3	36	385	251	592	9e-75	258
rs:WP_023316738	DNA topoisomerase III [Klebsiella pneumoniae].	39.03	351	204	4	36	385	251	592	9e-75	258
rs:WP_001478208	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	9e-75	258
rs:WP_001427702	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	9e-75	258
rs:WP_014908052	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	39.12	363	213	3	29	389	232	588	1e-74	257
rs:WP_039358423	DNA topoisomerase III [Pectobacterium carotovorum].	36.05	405	239	6	36	438	251	637	1e-74	258
rs:WP_042337355	hypothetical protein [Burkholderia ferrariae].	37.19	441	253	12	35	458	240	673	1e-74	259
rs:WP_032259514	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	1e-74	258
rs:WP_022633477	DNA topoisomerase III [Dickeya solani].	37.07	375	227	4	36	409	251	617	1e-74	258
rs:WP_032452512	DNA topoisomerase III [Klebsiella quasipneumoniae].	39.03	351	204	4	36	385	251	592	1e-74	258
rs:WP_016506274	DNA topoisomerase III [Salmonella enterica].	38.29	350	208	3	36	385	251	592	1e-74	258
rs:WP_013464239	MULTISPECIES: DNA topoisomerase III [Pseudoalteromonas].	39.30	374	215	2	36	406	251	615	1e-74	258
rs:WP_001235856	DNA topoisomerase III [Salmonella enterica].	38.29	350	208	3	36	385	251	592	1e-74	258
rs:WP_033102640	MULTISPECIES: DNA topoisomerase III [Alteromonadales].	39.30	374	215	2	36	406	251	615	1e-74	258
rs:WP_017491015	DNA topoisomerase III [gamma proteobacterium WG36].	37.04	405	237	5	36	438	251	639	1e-74	258
rs:WP_001616960	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	1e-74	258
rs:WP_001235870	DNA topoisomerase III [Salmonella enterica].	35.56	405	240	5	36	438	251	636	1e-74	258
rs:WP_017701728	DNA topoisomerase III [Pseudomonas syringae].	38.73	346	210	1	61	406	267	610	1e-74	258
rs:WP_039496146	DNA topoisomerase III [Pectobacterium carotovorum].	36.48	403	236	6	36	436	251	635	1e-74	258
rs:WP_047739134	DNA topoisomerase III [Pseudomonas chlororaphis].	36.94	379	236	2	31	408	236	612	1e-74	258
tr:F3CKY0_PSESG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	40.93	364	211	3	31	392	236	597	1e-74	257
rs:WP_008110196	DNA topoisomerase III [Pseudoalteromonas sp. BSi20311].	40.29	350	200	1	36	385	251	591	1e-74	258
rs:WP_046373372	DNA topoisomerase III [Serratia liquefaciens].	36.25	400	245	4	36	434	251	641	1e-74	258
rs:WP_021312943	DNA topoisomerase III [Klebsiella pneumoniae].	39.03	351	204	4	36	385	251	592	1e-74	258
rs:WP_029799342	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	41.58	303	170	1	36	338	255	550	1e-74	256
rs:WP_024599846	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	37.04	351	220	1	35	385	250	599	1e-74	258
rs:WP_005968748	DNA topoisomerase III [Pectobacterium wasabiae].	36.30	405	238	6	36	438	251	637	1e-74	258
rs:WP_044191484	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	1e-74	258
rs:WP_032422354	DNA topoisomerase III [Klebsiella pneumoniae].	39.03	351	204	4	36	385	251	592	1e-74	258
rs:WP_021556882	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	1e-74	258
rs:WP_048306940	DNA topoisomerase III [Halomonas sp. PR-M31].	36.76	389	231	2	31	415	238	615	1e-74	258
rs:WP_048383060	DNA topoisomerase III [Pseudomonas taetrolens].	37.50	360	223	1	61	420	267	624	1e-74	258
rs:WP_010436617	DNA topoisomerase III [Pseudomonas syringae].	36.90	374	233	2	36	408	241	612	1e-74	258
rs:WP_001497630	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	1e-74	258
rs:WP_015461373	MULTISPECIES: DNA topoisomerase III [Edwardsiella].	38.15	401	237	5	36	435	251	641	1e-74	258
rs:WP_023655212	DNA topoisomerase III [Erwinia piriflorinigrans].	39.60	351	204	3	36	386	251	593	1e-74	258
tr:I1E068_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	37.17	374	225	1	36	399	256	629	1e-74	258
rs:WP_024523753	DNA topoisomerase III [Edwardsiella hoshinae].	39.43	350	204	3	36	385	251	592	1e-74	258
rs:WP_028834920	MULTISPECIES: DNA topoisomerase III [Pseudoalteromonas].	39.30	374	215	2	36	406	251	615	1e-74	258
rs:WP_046939870	DNA topoisomerase III [Haemophilus haemolyticus].	37.67	369	222	2	36	404	260	620	1e-74	258
rs:WP_024486969	DNA topoisomerase III [Serratia fonticola].	36.90	374	224	4	36	407	251	614	1e-74	258
rs:WP_017684788	DNA topoisomerase III [Pseudomonas syringae].	38.44	346	211	1	61	406	267	610	1e-74	258
rs:WP_001465398	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	1e-74	258
rs:WP_038863407	DNA topoisomerase III [Cronobacter muytjensii].	39.43	350	204	3	36	385	251	592	1e-74	258
tr:F4TF90_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.29	350	208	3	36	385	260	601	1e-74	258
rs:WP_014069859	DNA topoisomerase III [Enterobacter asburiae].	38.57	350	207	3	36	385	251	592	1e-74	258
rs:WP_003300857	DNA topoisomerase III [Pseudomonas stutzeri].	39.26	349	211	1	65	413	271	618	1e-74	258
rs:WP_024528781	DNA topoisomerase III [Serratia fonticola].	36.90	374	224	4	36	407	251	614	1e-74	258
rs:WP_027620857	DNA topoisomerase III [Pseudomonas sp. URHB0015].	38.72	359	213	2	61	414	267	623	1e-74	258
rs:WP_043199457	DNA topoisomerase III [Pseudomonas putida].	39.47	342	205	1	67	408	273	612	1e-74	258
rs:WP_040148465	DNA topoisomerase III [Klebsiella pneumoniae].	38.57	350	207	3	36	385	251	592	1e-74	258
rs:WP_024221941	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	1e-74	258
rs:WP_043955306	DNA topoisomerase III [Enterobacter sp. YD4].	39.51	367	212	3	29	392	232	591	1e-74	256
rs:WP_048360801	DNA topoisomerase III [Pseudomonas deceptionensis].	38.15	346	212	1	61	406	267	610	1e-74	258
rs:WP_048260205	DNA topoisomerase III [Pectobacterium carotovorum].	36.54	405	237	6	36	438	251	637	2e-74	258
rs:WP_043212213	DNA topoisomerase III [Pseudomonas putida].	38.24	387	226	5	36	414	241	622	2e-74	258
rs:WP_045374815	DNA topoisomerase III [Enterobacter aerogenes].	38.75	351	205	4	36	385	251	592	2e-74	258
rs:WP_046985670	DNA topoisomerase III, partial [Thermomonas brevis].	38.75	351	205	6	104	454	1	341	2e-74	250
rs:WP_024601516	DNA topoisomerase III [Pseudoalteromonas atlantica].	39.84	374	213	3	36	406	251	615	2e-74	258
rs:WP_003877739	DNA topoisomerase III [Escherichia coli].	38.57	350	207	3	36	385	251	592	2e-74	258
rs:WP_001507459	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	2e-74	258
rs:WP_027919719	DNA topoisomerase III [Pseudomonas sp. URMO17WK12:I8].	38.40	375	225	3	67	438	273	644	2e-74	258
rs:WP_024232750	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	2e-74	258
rs:WP_012441306	DNA topoisomerase III [Erwinia tasmaniensis].	39.32	351	205	3	36	386	251	593	2e-74	257
tr:G6YQR7_9ALTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.47	484	259	8	28	459	298	770	2e-74	260
tr:H7E4P1_SALHO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.29	350	208	3	36	385	260	601	2e-74	258
tr:F9GN99_HAEHA	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.67	369	222	3	36	404	260	620	2e-74	258
rs:WP_047781318	DNA topoisomerase III [Pragia fontium].	37.47	387	226	5	36	414	251	629	2e-74	257
rs:WP_013025979	DNA topoisomerase III [Pantoea ananatis].	39.77	352	200	4	36	385	251	592	2e-74	257
rs:WP_001235883	DNA topoisomerase III [Salmonella bongori].	38.00	350	209	3	36	385	251	592	2e-74	257
rs:WP_008466850	DNA topoisomerase III [Pseudoalteromonas sp. BSi20439].	39.04	374	216	2	36	406	251	615	2e-74	258
rs:WP_047567107	DNA topoisomerase III [Serratia marcescens].	36.39	404	239	5	36	438	251	637	2e-74	257
rs:WP_038658888	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	37.07	375	227	4	36	409	251	617	2e-74	257
rs:WP_045048228	DNA topoisomerase III, partial [Rouxiella chamberiensis].	37.37	372	225	3	36	407	149	512	2e-74	255
rs:WP_033092471	DNA topoisomerase III [Colwellia psychrerythraea].	36.41	379	237	2	32	408	249	625	2e-74	258
rs:WP_003454892	DNA topoisomerase III [Pseudomonas aeruginosa].	35.12	430	260	7	32	454	237	654	2e-74	258
rs:WP_044649609	DNA topoisomerase III, partial [Klebsiella variicola].	38.75	351	205	4	36	385	184	525	2e-74	256
rs:WP_001235812	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	2e-74	258
rs:WP_042571552	DNA topoisomerase III [Pseudomonas simiae].	37.97	374	229	2	36	408	241	612	2e-74	258
rs:WP_029739826	DNA topoisomerase III [Enterobacter asburiae].	36.73	392	229	4	36	427	251	623	2e-74	257
rs:WP_048291992	DNA topoisomerase III [Klebsiella pneumoniae].	38.75	351	205	4	36	385	251	592	2e-74	258
rs:WP_041073385	DNA topoisomerase III [Pseudomonas sp. W15Feb9B].	38.33	347	212	1	61	407	267	611	2e-74	257
rs:WP_021515047	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	2e-74	258
rs:WP_001235880	DNA topoisomerase III [Salmonella enterica].	38.29	350	208	3	36	385	251	592	2e-74	258
rs:WP_046397481	DNA topoisomerase III [Photorhabdus luminescens].	37.40	369	221	4	35	402	250	609	2e-74	257
tr:W8UIN6_YEREN	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	36.27	386	237	4	36	420	251	628	2e-74	257
rs:WP_039487073	DNA topoisomerase III [Pectobacterium carotovorum].	35.64	404	242	5	36	438	251	637	2e-74	257
rs:WP_040089757	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	2e-74	257
rs:WP_032614657	DNA topoisomerase III [Pseudomonas syringae].	36.39	382	240	2	36	416	241	620	2e-74	258
rs:WP_020844018	DNA topoisomerase III [Salmonella bongori].	38.00	350	209	3	36	385	251	592	2e-74	257
rs:WP_041342545	DNA topoisomerase III [Marinobacter similis].	34.59	477	256	9	32	459	250	719	2e-74	259
rs:WP_032993914	DNA topoisomerase III [Cronobacter malonaticus].	39.14	350	205	3	36	385	251	592	2e-74	257
sp:TOP3_SALTI	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	38.29	350	208	3	36	385	251	592	2e-74	257
rs:WP_044349470	DNA topoisomerase III [Raoultella ornithinolytica].	37.94	369	221	3	36	404	251	611	2e-74	257
tr:A4JFS2_BURVG	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	38.40	375	221	2	35	401	251	623	2e-74	259
rs:WP_002433736	DNA topoisomerase III [Escherichia hermannii].	39.89	351	201	4	36	385	251	592	2e-74	257
rs:WP_001548631	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	2e-74	257
rs:WP_034940995	DNA topoisomerase III [Erwinia mallotivora].	39.71	350	203	3	36	385	251	592	2e-74	257
rs:WP_043865227	DNA topoisomerase III [Enterobacter aerogenes].	39.89	351	201	4	36	385	251	592	2e-74	257
rs:WP_034861907	DNA topoisomerase III [Enterobacteriaceae bacterium B14].	36.75	381	231	4	36	414	251	623	2e-74	257
rs:WP_040886141	DNA topoisomerase III [Marinobacterium stanieri].	38.86	350	206	2	36	385	251	592	2e-74	258
rs:WP_001748363	DNA topoisomerase III [Salmonella enterica].	38.29	350	208	3	36	385	251	592	2e-74	257
rs:WP_035342059	DNA topoisomerase III, partial [Dickeya sp. DW 0440].	37.67	369	218	4	36	402	46	404	2e-74	251
rs:WP_020325680	DNA topoisomerase III [Pseudomonas syringae].	38.44	346	211	1	61	406	267	610	2e-74	258
rs:WP_045069951	DNA topoisomerase III [Photobacterium leiognathi].	38.46	364	216	3	36	396	251	609	2e-74	257
rs:WP_024692225	DNA topoisomerase III [Pseudomonas syringae].	38.20	356	218	1	61	416	267	620	3e-74	257
rs:WP_032969960	DNA topoisomerase III [Cronobacter malonaticus].	39.14	350	205	3	36	385	251	592	3e-74	257
rs:WP_001235849	DNA topoisomerase III [Escherichia albertii].	38.57	350	207	3	36	385	251	592	3e-74	257
rs:WP_001524338	DNA topoisomerase III [Salmonella enterica].	38.29	350	208	3	36	385	251	592	3e-74	257
rs:WP_017825375	DNA topoisomerase III, partial [Clostridium botulinum].	36.27	397	236	4	36	425	232	618	3e-74	258
rs:WP_001508687	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	3e-74	257
rs:WP_032236924	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	3e-74	257
rs:WP_032176337	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	3e-74	257
rs:WP_005368918	DNA topoisomerase III [Photobacterium angustum].	38.57	350	210	2	36	385	251	595	3e-74	257
rs:WP_011264006	DNA topoisomerase III [Aliivibrio fischeri].	35.42	415	240	4	32	426	235	641	3e-74	257
rs:WP_014064795	DNA topoisomerase III [Haemophilus parainfluenzae].	38.23	361	215	2	36	396	256	608	3e-74	257
rs:WP_047293557	DNA topoisomerase III [Pseudomonas fluorescens].	38.33	347	212	1	61	407	267	611	3e-74	257
rs:WP_038930464	DNA topoisomerase III, partial [Yersinia pestis].	36.51	367	225	3	36	402	118	476	3e-74	253
rs:WP_022623227	DNA topoisomerase III [Pantoea ananatis].	39.71	350	203	3	36	385	251	592	3e-74	257
rs:WP_024960098	DNA topoisomerase III [Pseudomonas syringae].	38.20	356	218	1	61	416	267	620	3e-74	257
rs:WP_031291485	DNA topoisomerase III [Pseudomonas fluorescens].	37.97	374	229	2	36	408	241	612	3e-74	257
rs:WP_003226035	DNA topoisomerase III [Pseudomonas fluorescens].	38.33	347	212	1	61	407	267	611	3e-74	257
rs:WP_040477989	DNA topoisomerase III, partial [Halomonas smyrnensis].	36.72	384	230	2	35	416	242	614	3e-74	256
tr:U1S6K3_PSEFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	37.97	374	229	2	36	408	243	614	3e-74	257
rs:WP_009500211	DNA topoisomerase III [Haemophilus sp. oral taxon 851].	37.40	369	223	2	36	404	260	620	3e-74	257
rs:WP_044288115	DNA topoisomerase III [Pseudomonas fluorescens].	37.97	374	229	2	36	408	241	612	3e-74	257
rs:WP_010211314	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	37.97	374	229	2	36	408	241	612	3e-74	257
rs:WP_015964778	DNA topoisomerase III [Enterobacteriaceae bacterium strain FGI 57].	38.86	350	206	3	36	385	251	592	3e-74	257
rs:WP_014544395	DNA topoisomerase III [Erwinia sp. Ejp617].	39.03	351	206	3	36	386	251	593	3e-74	257
rs:WP_047542896	DNA topoisomerase III [Pseudomonas simiae].	37.97	374	229	2	36	408	241	612	3e-74	257
rs:WP_046075295	DNA topoisomerase III [Salinivibrio sp. KP-1].	40.00	350	202	2	36	385	251	592	3e-74	257
rs:WP_039262034	MULTISPECIES: DNA topoisomerase III [Enterobacter].	38.86	350	206	3	36	385	251	592	3e-74	256
rs:WP_003381830	DNA topoisomerase III [Pseudomonas syringae].	38.44	346	211	1	61	406	267	610	3e-74	257
rs:WP_029850627	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	41.58	303	170	1	36	338	255	550	3e-74	254
rs:WP_023182587	DNA topoisomerase III [Salmonella enterica].	38.80	384	219	5	29	409	232	602	3e-74	256
gp:CP010896_1975	DNA topoisomerase III [Pseudomonas fluorescens]	37.97	374	229	2	36	408	243	614	3e-74	257
rs:WP_024910835	DNA topoisomerase III [Serratia multitudinisentens].	36.63	374	225	4	36	407	251	614	3e-74	256
rs:WP_034064609	DNA topoisomerase III [Pseudomonas aeruginosa].	34.68	444	264	7	31	459	236	668	3e-74	258
rs:WP_024679664	DNA topoisomerase III [Pseudomonas syringae].	37.60	367	224	2	40	406	249	610	3e-74	257
rs:WP_015730446	DNA topoisomerase III [Pectobacterium wasabiae].	36.30	405	238	6	36	438	251	637	3e-74	256
rs:WP_024696781	DNA topoisomerase III [Pseudomonas syringae].	37.33	375	226	3	36	406	241	610	4e-74	257
rs:WP_042609385	DNA topoisomerase III [Pseudomonas fluorescens].	37.75	347	214	1	61	407	267	611	4e-74	257
rs:WP_039537398	DNA topoisomerase III [Pectobacterium carotovorum].	36.05	405	239	6	36	438	251	637	4e-74	256
rs:WP_019364549	DNA topoisomerase III [Pseudomonas luteola].	36.53	386	235	4	36	414	241	623	4e-74	257
rs:WP_044308340	DNA topoisomerase III [Pseudomonas syringae].	36.39	382	240	2	36	416	241	620	4e-74	257
tr:Q3II06_PSEHT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	38.60	342	207	2	35	376	233	571	4e-74	256
rs:WP_039549510	DNA topoisomerase III [Pectobacterium carotovorum].	36.05	405	239	6	36	438	251	637	4e-74	256
rs:WP_016414676	DNA topoisomerase III [Halomonas anticariensis].	37.20	379	227	1	31	409	238	605	4e-74	256
rs:WP_015740971	DNA topoisomerase III [Siccibacter turicensis].	39.32	351	203	4	36	385	251	592	4e-74	256
rs:WP_001235788	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	4e-74	257
rs:WP_046618303	DNA topoisomerase III [Enterobacter cloacae].	38.86	350	206	3	36	385	251	592	4e-74	256
rs:WP_017430535	DNA topoisomerase III [Halomonas jeotgali].	37.59	407	229	4	35	437	242	627	4e-74	256
rs:WP_047768394	DNA topoisomerase III [Xenorhabdus griffiniae].	39.27	354	203	4	103	455	131	473	4e-74	253
rs:WP_040062870	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	4e-74	256
rs:WP_010223989	DNA topoisomerase III [Pseudomonas sp. HYS].	38.27	371	222	2	67	432	273	641	4e-74	256
rs:WP_033145248	DNA topoisomerase III [Enterobacter cloacae].	38.86	350	206	3	36	385	251	592	4e-74	256
rs:WP_039565798	DNA topoisomerase III [Serratia marcescens].	36.14	404	240	5	36	438	251	637	4e-74	256
rs:WP_023302569	DNA topoisomerase III [Klebsiella pneumoniae].	38.97	349	203	4	38	385	253	592	4e-74	256
rs:WP_036994754	DNA topoisomerase III [Pseudomonas sp. P482].	38.27	371	222	2	67	432	273	641	4e-74	256
rs:WP_013983541	DNA topoisomerase III [Pseudomonas stutzeri].	39.26	349	211	1	65	413	271	618	4e-74	256
rs:WP_024551811	DNA topoisomerase III [Franconibacter helveticus].	38.21	369	220	3	36	404	251	611	4e-74	256
rs:WP_048402419	DNA topoisomerase III [Pseudomonas sp. DSM 28140].	36.44	376	231	3	36	408	241	611	4e-74	256
rs:WP_009683128	DNA topoisomerase III, partial [Pseudomonas sp. TJI-51].	39.76	327	195	1	82	408	2	326	5e-74	249
rs:WP_005893387	DNA topoisomerase III [Pseudomonas coronafaciens].	36.83	372	232	2	36	406	241	610	5e-74	256
rs:WP_023184966	DNA topoisomerase III [Salmonella enterica].	38.29	350	208	3	36	385	251	592	5e-74	256
rs:WP_048371325	DNA topoisomerase III [Pseudomonas sp. DSM 29165].	37.36	356	221	1	61	416	267	620	5e-74	256
rs:WP_045062705	DNA topoisomerase III [Photobacterium leiognathi].	38.46	364	216	3	36	396	251	609	5e-74	257
rs:WP_012848346	MULTISPECIES: DNA topoisomerase III [Edwardsiella].	37.91	401	238	5	36	435	251	641	5e-74	256
rs:WP_001637972	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	5e-74	256
rs:WP_041454535	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	38.30	342	208	1	35	376	250	588	5e-74	256
rs:WP_038642446	DNA topoisomerase III [Pseudoalteromonas sp. OCN003].	37.03	370	224	2	36	405	251	611	5e-74	256
rs:WP_035782818	DNA topoisomerase III [Clostridium botulinum].	36.27	397	236	4	36	425	232	618	5e-74	258
rs:WP_039286594	DNA topoisomerase III [Pectobacterium carotovorum].	36.23	403	237	6	36	436	251	635	5e-74	256
rs:WP_029863194	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	41.58	303	170	1	36	338	255	550	5e-74	254
rs:WP_032860216	DNA topoisomerase III [Pseudomonas sp. FH4].	37.27	381	221	3	61	436	267	634	5e-74	256
rs:WP_044311497	DNA topoisomerase III [Pseudomonas syringae].	38.20	356	218	1	61	416	267	620	5e-74	256
rs:WP_047061605	DNA topoisomerase III [Enterobacter asburiae].	36.48	392	230	4	36	427	251	623	5e-74	256
rs:WP_032331693	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	5e-74	256
rs:WP_024013263	DNA topoisomerase III [Pseudomonas moraviensis].	37.75	347	214	1	61	407	267	611	5e-74	256
tr:A0A0A5LTA1_SERMA	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	36.39	404	239	5	36	438	251	637	5e-74	256
rs:WP_010365922	DNA topoisomerase III [Pseudoalteromonas citrea].	39.32	351	207	1	35	385	250	594	5e-74	256
rs:WP_001235854	DNA topoisomerase III [Salmonella enterica].	38.29	350	208	3	36	385	251	592	5e-74	256
rs:WP_046093421	DNA topoisomerase III [Salmonella enterica].	38.29	350	208	3	36	385	251	592	6e-74	256
rs:WP_046878585	DNA topoisomerase III [Klebsiella oxytoca].	38.75	351	205	4	36	385	251	592	6e-74	256
rs:WP_007019943	DNA topoisomerase III [Neptuniibacter caesariensis].	35.34	382	237	3	36	417	251	622	6e-74	256
rs:WP_003801585	DNA topoisomerase III [Escherichia coli].	38.29	350	208	3	36	385	251	592	6e-74	256
rs:WP_001516287	MULTISPECIES: DNA topoisomerase III [Escherichia].	38.00	350	209	3	36	385	251	592	6e-74	256
rs:WP_045336885	hypothetical protein [Enterobacter asburiae].	35.05	428	261	6	35	459	250	663	6e-74	257
rs:WP_025153076	DNA topoisomerase III [Morganella morganii].	38.75	351	207	3	36	386	251	593	6e-74	256
rs:WP_048366282	DNA topoisomerase III [Pseudomonas sp. DSM 29166].	36.44	376	231	3	36	408	241	611	6e-74	256
rs:WP_047536590	DNA topoisomerase III [Shewanella sp. ZOR0012].	37.67	377	228	3	35	410	250	620	6e-74	256
rs:WP_036414934	DNA topoisomerase III [Morganella morganii].	38.08	365	215	4	22	386	240	593	6e-74	256
rs:WP_036966356	DNA topoisomerase III [Pseudoalteromonas lipolytica].	39.89	351	202	1	36	386	251	592	6e-74	256
rs:WP_038354286	DNA topoisomerase III [Escherichia sp. HT073016].	38.00	350	209	3	36	385	251	592	6e-74	256
rs:WP_015840206	DNA topoisomerase III [Pectobacterium carotovorum].	35.64	404	242	5	36	438	251	637	6e-74	256
rs:WP_016248644	MULTISPECIES: DNA topoisomerase III [Escherichia].	38.00	350	209	3	36	385	251	592	6e-74	256
rs:WP_023179729	DNA topoisomerase III [Salmonella enterica].	38.29	350	208	3	36	385	251	592	6e-74	256
rs:WP_047648066	DNA topoisomerase III [Enterobacter asburiae].	36.48	392	230	4	36	427	251	623	6e-74	256
gpu:KM655310_3	putative DNA topoisomerase [uncultured bacterium]	88.72	133	15	0	29	161	244	376	7e-74	249
rs:WP_045792448	DNA topoisomerase III [Pseudomonas fluorescens].	37.70	374	230	2	36	408	241	612	7e-74	256
rs:WP_024661949	DNA topoisomerase III [Pseudomonas syringae].	36.39	382	240	2	36	416	241	620	7e-74	256
rs:WP_048390366	DNA topoisomerase III [Pseudomonas sp. DSM 28141].	37.36	356	221	1	61	416	267	620	7e-74	256
rs:WP_004235547	DNA topoisomerase III [Morganella morganii].	38.08	365	215	4	22	386	240	593	7e-74	256
rs:WP_045347463	DNA topoisomerase III [Enterobacter cloacae].	38.57	350	207	3	36	385	251	592	7e-74	256
rs:WP_037399017	MULTISPECIES: DNA topoisomerase III [Serratia].	36.60	377	225	5	36	408	251	617	7e-74	256
rs:WP_008807619	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	38.75	351	205	4	36	385	251	592	7e-74	256
rs:WP_004418049	DNA topoisomerase III [Pseudomonas syringae].	37.05	386	232	3	36	416	241	620	7e-74	256
rs:WP_016160745	MULTISPECIES: DNA topoisomerase III [Klebsiella].	38.75	351	205	4	36	385	251	592	7e-74	256
rs:WP_047730551	DNA topoisomerase III [Serratia marcescens].	36.39	404	239	5	36	438	251	637	8e-74	256
rs:WP_008911016	DNA topoisomerase III [Providencia burhodogranariea].	37.01	381	231	4	36	416	251	622	8e-74	256
rs:WP_032660787	DNA topoisomerase III [Pseudomonas syringae].	37.92	356	219	1	61	416	267	620	8e-74	256
rs:WP_043220266	DNA topoisomerase III [Pseudomonas balearica].	39.24	344	207	1	65	408	271	612	8e-74	256
rs:WP_023297427	MULTISPECIES: DNA topoisomerase III [Klebsiella].	38.75	351	205	4	36	385	251	592	8e-74	256
gp:CP005975_5245	DNA topoisomerase III [Pseudomonas fluorescens PICF7]	37.70	374	230	2	36	408	243	614	8e-74	256
rs:WP_033949820	DNA topoisomerase III [Pseudomonas aeruginosa].	34.68	444	264	7	31	459	236	668	8e-74	258
rs:WP_042714821	DNA topoisomerase III [Enterobacter sp. B509].	38.57	350	207	3	36	385	251	592	8e-74	256
rs:WP_045158624	DNA topoisomerase III [Pseudomonas stutzeri].	39.26	349	211	1	65	413	271	618	8e-74	256
rs:WP_024562713	DNA topoisomerase III, partial [Cronobacter turicensis].	38.86	350	206	3	36	385	201	542	8e-74	254
rs:WP_032754074	DNA topoisomerase III [Klebsiella pneumoniae].	38.75	351	205	4	36	385	251	592	8e-74	256
rs:WP_003441919	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	37.64	348	215	1	61	408	267	612	8e-74	256
rs:WP_042926554	MULTISPECIES: DNA topoisomerase III [Pseudomonas stutzeri group].	38.97	349	212	1	65	413	271	618	8e-74	256
rs:WP_043147568	DNA topoisomerase III [Serratia marcescens].	36.14	404	240	5	36	438	251	637	8e-74	256
rs:WP_016567955	DNA topoisomerase III [Pseudomonas syringae].	37.92	356	219	1	61	416	267	620	9e-74	256
rs:WP_036417289	DNA topoisomerase III [Morganella sp. EGD-HP17].	38.08	365	215	4	22	386	240	593	9e-74	256
rs:WP_032218329	DNA topoisomerase III [Escherichia coli].	38.00	350	209	3	36	385	251	592	9e-74	256
rs:WP_039505489	DNA topoisomerase III [Pectobacterium carotovorum].	36.05	405	239	6	36	438	251	637	9e-74	255
tr:U4P5E3_CLOBB	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	36.27	397	236	4	36	425	227	613	9e-74	257
rs:WP_041035424	DNA topoisomerase III [Serratia marcescens].	36.39	404	239	5	36	438	251	637	9e-74	255
rs:WP_010430094	DNA topoisomerase III [Enterobacter mori].	38.57	350	207	3	36	385	251	592	9e-74	255
rs:WP_043298804	DNA topoisomerase III [Pseudomonas sp. HMP271].	38.50	374	227	2	36	408	244	615	9e-74	256
rs:WP_046050872	DNA topoisomerase III [Yersinia enterocolitica].	36.01	386	238	4	36	420	251	628	1e-73	255
rs:WP_019079527	DNA topoisomerase III [Yersinia enterocolitica].	36.01	386	238	4	36	420	251	628	1e-73	255
rs:WP_048234250	DNA topoisomerase III [Escherichia coli].	36.39	404	239	5	36	438	251	637	1e-73	255
rs:WP_003371547	DNA topoisomerase III [Clostridium botulinum].	35.78	408	245	4	25	425	222	619	1e-73	257
tr:W0UKE1_YEREN	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	36.01	386	238	4	36	420	252	629	1e-73	255
rs:WP_038441873	DNA topoisomerase III [Pseudomonas fluorescens].	36.36	407	240	4	36	436	241	634	1e-73	256
rs:WP_047354069	DNA topoisomerase III [Enterobacter sp. GN02315].	38.57	350	207	3	36	385	251	592	1e-73	255
rs:WP_005817765	DNA topoisomerase III [Actinobacillus minor].	38.00	350	209	2	36	385	252	593	1e-73	255
tr:F3GEC0_PSESJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	37.92	356	219	1	61	416	267	620	1e-73	255
rs:WP_016266194	DNA topoisomerase III [Yersinia enterocolitica].	36.01	386	238	4	36	420	251	628	1e-73	255
rs:WP_015870990	DNA topoisomerase III [Edwardsiella ictaluri].	37.34	383	229	5	36	417	251	623	1e-73	255
rs:WP_042319450	DNA topoisomerase III [Citrobacter farmeri].	37.43	350	211	3	36	385	251	592	1e-73	255
rs:WP_014699893	MULTISPECIES: DNA topoisomerase III [Pectobacterium].	36.30	405	238	6	36	438	251	637	1e-73	255
rs:WP_003403627	DNA topoisomerase III [Pseudomonas syringae].	38.22	348	213	1	61	408	267	612	1e-73	256
rs:WP_033634801	DNA topoisomerase III [Serratia marcescens].	36.39	404	239	5	36	438	251	637	1e-73	255
rs:WP_005166139	DNA topoisomerase III [Yersinia enterocolitica].	36.01	386	238	4	36	420	251	628	1e-73	255
rs:WP_012423320	DNA topoisomerase III [Clostridium botulinum].	36.27	397	236	4	36	425	232	618	1e-73	257
rs:WP_029592603	DNA topoisomerase III [Franconibacter pulveris].	38.75	351	205	4	36	385	251	592	1e-73	256
rs:WP_024638443	DNA topoisomerase III [Pseudomonas syringae].	37.93	348	214	1	61	408	267	612	1e-73	256
rs:WP_047576711	DNA topoisomerase III [Pseudomonas syringae].	36.36	374	235	2	36	408	241	612	1e-73	256
rs:WP_020283118	DNA topoisomerase III [Yersinia enterocolitica].	36.01	386	238	4	36	420	252	629	1e-73	255
rs:WP_024642909	DNA topoisomerase III [Pseudomonas syringae].	38.22	348	213	1	61	408	267	612	1e-73	256
rs:WP_024559605	DNA topoisomerase III [Franconibacter pulveris].	37.84	370	220	4	36	404	251	611	1e-73	255
rs:WP_032899009	DNA topoisomerase III [Yersinia bercovieri].	36.50	389	234	5	36	420	251	630	1e-73	255
rs:WP_038657937	DNA topoisomerase III [Pseudomonas stutzeri].	37.99	379	233	2	36	413	241	618	1e-73	255
rs:WP_024689860	DNA topoisomerase III [Pseudomonas syringae].	38.44	346	211	1	61	406	267	610	1e-73	256
rs:WP_004412596	DNA topoisomerase III [Pseudomonas syringae].	37.92	356	219	1	61	416	267	620	1e-73	256
rs:WP_046596356	DNA topoisomerase III [Salmonella enterica].	38.00	350	209	3	36	385	251	592	1e-73	255
gp:CP011421_1198	DNA topoisomerase III [Klebsiella pneumoniae]	38.75	351	205	4	36	385	251	592	1e-73	255
rs:WP_024558046	DNA topoisomerase III [Franconibacter pulveris].	38.92	352	205	4	36	386	251	593	1e-73	255
rs:WP_017353184	DNA topoisomerase III [Clostridium botulinum].	36.27	397	236	4	36	425	232	618	1e-73	257
tr:C4S6E6_YERBE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	36.50	389	234	5	36	420	252	631	1e-73	255
rs:WP_003423916	DNA topoisomerase III [Pseudomonas syringae].	37.05	386	232	3	36	416	241	620	1e-73	255
rs:WP_012449561	DNA topoisomerase III [Clostridium botulinum].	35.54	408	246	4	25	425	222	619	1e-73	257
rs:WP_046356583	DNA topoisomerase III [Pseudoalteromonas luteoviolacea].	37.39	353	214	2	33	385	248	593	1e-73	255
rs:WP_038415875	DNA topoisomerase III [Enterobacter cloacae].	38.57	350	207	3	36	385	251	592	1e-73	255
rs:WP_024647908	DNA topoisomerase III [Pseudomonas syringae].	37.92	356	219	1	61	416	267	620	1e-73	255
rs:WP_038877225	DNA topoisomerase III [Serratia marcescens].	36.39	404	239	5	36	438	251	637	1e-73	255
rs:WP_024652300	DNA topoisomerase III [Pseudomonas syringae].	38.22	348	213	1	61	408	267	612	1e-73	255
rs:WP_048256990	DNA topoisomerase III [Pectobacterium carotovorum].	35.64	404	242	5	36	438	251	637	1e-73	255
rs:WP_014821142	DNA topoisomerase III [Pseudomonas stutzeri].	38.53	353	216	1	61	413	267	618	1e-73	255
rs:WP_025259685	DNA topoisomerase III [Pseudomonas cichorii].	36.63	374	234	2	36	408	241	612	1e-73	255
rs:WP_024683169	DNA topoisomerase III [Pseudomonas syringae].	37.92	356	219	1	61	416	267	620	1e-73	255
rs:WP_020827202	MULTISPECIES: DNA topoisomerase III [Serratia].	36.00	400	246	4	36	434	251	641	1e-73	255
rs:WP_045353661	DNA topoisomerase III [Enterobacter asburiae].	36.11	396	226	5	36	427	251	623	1e-73	255
rs:WP_023324481	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	38.57	350	207	3	36	385	251	592	1e-73	255
rs:WP_039029035	DNA topoisomerase III [Leclercia adecarboxylata].	36.59	369	226	3	36	404	251	611	1e-73	254
rs:WP_039277542	DNA topoisomerase III [Pectobacterium carotovorum].	35.73	403	243	5	36	438	251	637	1e-73	255
rs:WP_025303086	DNA topoisomerase III [Serratia marcescens].	36.14	404	240	5	36	438	251	637	1e-73	255
rs:WP_024669068	DNA topoisomerase III [Pseudomonas syringae].	38.44	346	211	1	61	406	267	610	2e-73	255
rs:WP_024664267	DNA topoisomerase III [Pseudomonas syringae].	37.92	356	219	1	61	416	267	620	2e-73	255
rs:WP_034887878	DNA topoisomerase III [Erwinia typographi].	39.14	350	205	3	36	385	251	592	2e-73	254
rs:WP_045333361	DNA topoisomerase III [Enterobacter cloacae].	38.57	350	207	3	36	385	251	592	2e-73	254
rs:WP_023305946	MULTISPECIES: DNA topoisomerase III [Enterobacter].	38.57	350	207	3	36	385	251	592	2e-73	255
rs:WP_046235877	DNA topoisomerase III [Pseudomonas syringae pv. coryli].	37.92	356	219	1	61	416	267	620	2e-73	255
rs:WP_012145443	MULTISPECIES: DNA topoisomerase III [Serratia].	36.73	373	226	4	36	407	251	614	2e-73	255
rs:WP_048243875	DNA topoisomerase III [Enterobacter cloacae].	38.57	350	207	3	36	385	251	592	2e-73	254
tr:W1W148_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.49	477	273	7	24	459	223	691	2e-73	256
rs:WP_004410753	DNA topoisomerase III [Pseudomonas syringae].	37.92	356	219	1	61	416	267	620	2e-73	255
rs:WP_012667948	DNA topoisomerase III [Erwinia pyrifoliae].	38.75	351	207	3	36	386	251	593	2e-73	255
rs:WP_023299889	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	38.57	350	207	3	36	385	251	592	2e-73	254
rs:WP_047653643	DNA topoisomerase III [Enterobacter cloacae].	38.57	350	207	3	36	385	251	592	2e-73	254
rs:WP_012765573	MULTISPECIES: DNA topoisomerase III [Dickeya].	36.80	375	227	4	36	408	251	617	2e-73	254
rs:WP_006322602	DNA topoisomerase III [Serratia plymuthica].	36.10	374	227	4	36	407	251	614	2e-73	254
rs:WP_040155132	DNA topoisomerase III [Yersinia ruckeri].	37.03	370	223	4	36	404	251	611	2e-73	254
rs:WP_003432932	DNA topoisomerase III [Pseudomonas syringae].	36.36	374	235	2	36	408	241	612	2e-73	255
rs:WP_011816425	DNA topoisomerase III [Yersinia enterocolitica].	36.32	380	233	4	36	414	252	623	2e-73	254
rs:WP_022647797	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	38.57	350	207	3	36	385	251	592	2e-73	254
rs:WP_004140407	DNA topoisomerase III [Klebsiella pneumoniae].	38.75	351	205	4	36	385	251	592	2e-73	255
rs:WP_032617695	DNA topoisomerase III [Leclercia adecarboxylata].	36.59	369	226	3	36	404	251	611	2e-73	254
rs:WP_046898907	DNA topoisomerase III [Serratia marcescens].	36.14	404	240	5	36	438	251	637	2e-73	254
rs:WP_004719880	DNA topoisomerase III [Yersinia ruckeri].	37.03	370	223	4	36	404	251	611	2e-73	254
rs:WP_048321660	DNA topoisomerase III [Serratia marcescens].	36.14	404	240	5	36	438	251	637	2e-73	254
rs:WP_042524880	DNA topoisomerase III [Yersinia ruckeri].	37.03	370	223	4	36	404	251	611	2e-73	254
rs:WP_044551747	DNA topoisomerase III [Serratia liquefaciens].	36.55	383	233	4	36	417	251	624	2e-73	254
rs:WP_039038404	DNA topoisomerase III [Pseudoalteromonas sp. ECSMB14103].	39.14	350	204	1	36	385	251	591	2e-73	254
rs:WP_035894586	DNA topoisomerase III [Kluyvera ascorbata].	39.03	351	204	4	36	385	251	592	2e-73	254
tr:D4E5Q2_SEROD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	36.32	380	232	4	36	414	15	385	2e-73	249
rs:WP_004945367	DNA topoisomerase III [Serratia plymuthica].	36.73	373	226	4	36	407	251	614	2e-73	254
rs:WP_033647606	DNA topoisomerase III [Serratia marcescens].	36.14	404	240	5	36	438	251	637	2e-73	254
rs:WP_042661428	DNA topoisomerase III [Yersinia enterocolitica].	36.32	380	233	4	36	414	251	622	2e-73	254
rs:WP_032657921	DNA topoisomerase III [Enterobacter sp. DC1].	38.57	350	207	3	36	385	251	592	2e-73	254
rs:WP_047744468	DNA topoisomerase III [Enterobacter cloacae].	38.29	350	208	3	36	385	251	592	2e-73	254
rs:WP_040017237	DNA topoisomerase III [Enterobacter ludwigii].	38.29	350	208	3	36	385	251	592	2e-73	254
rs:WP_048329637	DNA topoisomerase III [Pseudomonas stutzeri].	39.54	349	210	1	65	413	271	618	2e-73	254
rs:WP_005617231	DNA topoisomerase III [Actinobacillus pleuropneumoniae].	38.00	350	209	2	36	385	252	593	2e-73	254
rs:WP_005600974	DNA topoisomerase III [Actinobacillus pleuropneumoniae].	38.00	350	209	2	36	385	252	593	2e-73	254
rs:WP_008132140	DNA topoisomerase III [Pseudoalteromonas sp. BSi20480].	39.14	350	204	1	36	385	251	591	2e-73	254
rs:WP_023311262	MULTISPECIES: DNA topoisomerase III [Enterobacter].	36.22	392	231	4	36	427	251	623	2e-73	254
rs:WP_014831514	DNA topoisomerase III [Enterobacter cloacae].	38.57	350	207	3	36	385	251	592	2e-73	254
rs:WP_041083732	DNA topoisomerase III [Clostridium botulinum].	36.02	397	237	4	36	425	232	618	2e-73	256
gp:CP007439_2807	DNA topoisomerase III [Serratia plymuthica]	36.73	373	226	4	36	407	251	614	2e-73	254
rs:WP_026971115	DNA topoisomerase III [Aliagarivorans marinus].	38.07	352	214	2	36	386	251	599	2e-73	255
tr:B3GXI1_ACTP7	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.00	350	209	2	36	385	259	600	2e-73	254
rs:WP_010200379	DNA topoisomerase III, partial [Pseudomonas amygdali].	35.86	382	242	2	36	416	111	490	2e-73	251
rs:WP_039103122	DNA topoisomerase III [Klebsiella variicola].	38.75	351	205	4	36	385	251	592	2e-73	254
rs:WP_021503851	MULTISPECIES: DNA topoisomerase III [Serratia].	36.14	404	240	5	36	438	251	637	2e-73	254
rs:WP_047062623	DNA topoisomerase III [Enterobacter cloacae].	38.29	350	208	3	36	385	251	592	2e-73	254
rs:WP_046621085	MULTISPECIES: DNA topoisomerase III [Klebsiella].	38.75	351	205	4	36	385	251	592	2e-73	254
rs:WP_027898417	DNA topoisomerase III [Pseudomonas syringae].	37.78	352	211	2	65	410	271	620	3e-73	254
rs:WP_029093488	DNA topoisomerase III [Budvicia aquatica].	38.21	369	220	3	36	404	251	611	3e-73	254
rs:WP_019452756	DNA topoisomerase III [Serratia marcescens].	36.14	404	240	5	36	438	251	637	3e-73	254
rs:WP_048273653	DNA topoisomerase III [Pluralibacter gergoviae].	38.57	350	207	3	36	385	251	592	3e-73	254
rs:WP_046079688	DNA topoisomerase III [Halomonas sp. HG01].	36.46	384	231	2	35	416	242	614	3e-73	255
rs:WP_028017189	DNA topoisomerase III [Enterobacter cloacae].	38.29	350	208	3	36	385	251	592	3e-73	254
rs:WP_025204419	DNA topoisomerase III [Enterobacter cloacae].	38.29	350	208	3	36	385	251	592	3e-73	254
rs:WP_013813220	MULTISPECIES: DNA topoisomerase III [Serratia].	36.73	373	226	4	36	407	251	614	3e-73	254
rs:WP_046479673	DNA topoisomerase III [Citrobacter amalonaticus].	37.43	350	211	3	36	385	251	592	3e-73	254
rs:WP_043142985	DNA topoisomerase III [Serratia marcescens].	36.14	404	240	5	36	438	251	637	3e-73	254
rs:WP_045844069	DNA topoisomerase III [Yersinia ruckeri].	37.03	370	223	4	36	404	251	611	3e-73	254
rs:WP_020884435	MULTISPECIES: DNA topoisomerase III [Enterobacter].	38.29	350	208	3	36	385	251	592	3e-73	254
rs:WP_004932196	MULTISPECIES: DNA topoisomerase III [Serratia].	36.14	404	240	5	36	438	251	637	3e-73	254
rs:WP_047651931	DNA topoisomerase III [Enterobacter sp. UCD-UG_FMILLET].	38.57	350	207	3	36	385	251	592	3e-73	254
rs:WP_024676485	DNA topoisomerase III [Pseudomonas syringae].	37.36	356	221	1	61	416	267	620	3e-73	254
rs:WP_033643309	DNA topoisomerase III [Serratia marcescens].	36.14	404	240	5	36	438	251	637	3e-73	254
rs:WP_046270416	DNA topoisomerase III [Pseudomonas syringae].	37.92	356	219	1	61	416	267	620	3e-73	254
tr:G8LKH3_ENTCL	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.29	350	208	3	36	385	257	598	3e-73	254
rs:WP_048252515	DNA topoisomerase III [Pluralibacter gergoviae].	38.57	350	207	3	36	385	251	592	3e-73	254
rs:WP_023620725	MULTISPECIES: DNA topoisomerase III [Enterobacter].	38.57	350	207	3	36	385	251	592	3e-73	254
rs:WP_039344884	DNA topoisomerase III [Pectobacterium carotovorum].	34.73	406	243	6	36	438	251	637	3e-73	254
rs:WP_016927481	MULTISPECIES: DNA topoisomerase III [Serratia].	36.14	404	240	5	36	438	251	637	3e-73	254
rs:WP_014597325	DNA topoisomerase III [Pseudomonas stutzeri].	38.97	349	212	1	65	413	271	618	3e-73	254
rs:WP_017134367	DNA topoisomerase III [Pseudomonas agarici].	37.30	378	232	2	60	434	266	641	3e-73	254
rs:WP_025988385	DNA topoisomerase III [Burkholderia pseudomallei].	34.60	422	263	6	36	454	241	652	3e-73	255
rs:WP_032467116	DNA topoisomerase III [Yersinia pseudotuberculosis].	36.32	380	233	4	36	414	251	622	3e-73	254
rs:WP_032817148	DNA topoisomerase III [Yersinia rohdei].	36.32	380	233	4	36	414	251	622	3e-73	254
rs:WP_047348900	DNA topoisomerase III [Enterobacter sp. GN03164].	38.57	350	207	3	36	385	251	592	3e-73	254
rs:WP_006794257	DNA topoisomerase III [Alteromonadales bacterium TW-7].	38.86	350	205	1	36	385	251	591	3e-73	254
rs:WP_032823989	DNA topoisomerase III [Haemophilus influenzae].	38.57	350	207	2	36	385	260	601	3e-73	254
rs:WP_027669479	DNA topoisomerase III [Rheinheimera baltica].	38.03	355	212	2	36	385	251	602	3e-73	254
rs:WP_011267536	DNA topoisomerase III [Pseudomonas syringae].	38.22	348	213	1	61	408	267	612	3e-73	254
rs:WP_024551116	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	38.86	350	206	3	36	385	251	592	3e-73	254
rs:WP_048286709	DNA topoisomerase III [Pluralibacter gergoviae].	38.86	350	206	3	36	385	251	592	4e-73	254
rs:WP_047719381	DNA topoisomerase III [Enterobacter cloacae].	38.29	350	208	3	36	385	251	592	4e-73	254
rs:WP_046005476	DNA topoisomerase III [Pseudoalteromonas rubra].	35.89	404	246	2	6	409	224	614	4e-73	254
rs:WP_015378097	DNA topoisomerase III [Serratia marcescens].	36.14	404	240	5	36	438	251	637	4e-73	254
rs:WP_045331141	DNA topoisomerase III [Enterobacter cloacae].	38.29	350	208	3	36	385	251	592	4e-73	254
rs:WP_016588639	DNA topoisomerase III, partial [Yersinia pestis].	36.51	367	225	3	36	402	251	609	4e-73	253
rs:WP_017384681	MULTISPECIES: DNA topoisomerase III [Enterobacter].	38.29	350	208	3	36	385	251	592	4e-73	254
rs:WP_010798937	DNA topoisomerase III [Pseudomonas sp. HPB0071].	36.27	386	236	4	36	414	241	623	4e-73	254
rs:WP_009838492	DNA topoisomerase III [Pseudoalteromonas tunicata].	36.58	380	232	1	36	415	251	621	4e-73	253
rs:WP_033848526	DNA topoisomerase III [Yersinia wautersii].	36.32	380	233	4	36	414	251	622	4e-73	254
rs:WP_043000912	MULTISPECIES: DNA topoisomerase III [Citrobacter].	37.14	350	212	3	36	385	251	592	4e-73	254
rs:WP_032673185	DNA topoisomerase III [Enterobacter sp. BIDMC 27].	38.29	350	208	3	36	385	251	592	4e-73	254
rs:WP_032619841	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	38.29	350	208	3	36	385	251	592	4e-73	254
rs:WP_045338463	DNA topoisomerase III [Enterobacter cloacae].	38.29	350	208	3	36	385	251	592	4e-73	254
rs:WP_020289917	DNA topoisomerase III [Pseudomonas sp. CFII64].	36.10	374	236	2	36	408	241	612	4e-73	254
rs:WP_039295725	DNA topoisomerase III [Pectobacterium atrosepticum].	36.05	405	239	6	36	438	251	637	4e-73	254
rs:WP_045307963	DNA topoisomerase III [Enterobacter sp. 36796].	38.29	350	208	3	36	385	251	592	4e-73	254
rs:WP_039310260	DNA topoisomerase III [Pectobacterium atrosepticum].	36.05	405	239	6	36	438	251	637	5e-73	253
rs:WP_019405243	DNA topoisomerase III [Pseudomonas stutzeri].	38.97	349	212	1	65	413	271	618	5e-73	254
rs:WP_004243257	DNA topoisomerase III [Proteus mirabilis].	39.60	351	202	4	36	385	251	592	5e-73	254
rs:WP_004169946	DNA topoisomerase III [Erwinia amylovora].	39.32	351	205	3	36	386	251	593	5e-73	253
rs:WP_017245828	DNA topoisomerase III [Pseudomonas stutzeri].	38.97	349	212	1	65	413	271	618	5e-73	254
rs:WP_038979877	MULTISPECIES: DNA topoisomerase III [Enterobacter].	38.57	350	207	3	36	385	251	592	5e-73	253
rs:WP_048240962	DNA topoisomerase III [Enterobacter cloacae].	38.29	350	208	3	36	385	251	592	5e-73	253
rs:WP_042287548	DNA topoisomerase III [Citrobacter sedlakii].	35.82	402	238	5	36	437	251	632	5e-73	254
rs:WP_048027509	MULTISPECIES: DNA topoisomerase III [Leclercia].	38.29	350	208	3	36	385	251	592	5e-73	253
rs:WP_020947509	hypothetical protein [Klebsiella pneumoniae].	38.75	351	205	4	36	385	251	592	5e-73	253
rs:WP_047352559	DNA topoisomerase III [Enterobacter sp. GN02616].	38.57	350	207	3	36	385	251	592	5e-73	253
rs:WP_022650874	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	38.29	350	208	3	36	385	251	592	5e-73	253
rs:WP_047023740	DNA topoisomerase III [Enterobacter sp. GN02174].	38.57	350	207	3	36	385	251	592	6e-73	253
rs:WP_006233033	DNA topoisomerase III [Photobacterium profundum].	37.68	353	217	2	36	385	251	603	6e-73	253
rs:WP_032229490	DNA topoisomerase III [Escherichia coli].	37.71	350	210	3	36	385	251	592	6e-73	253
rs:WP_047174037	DNA topoisomerase III [Enterobacter cloacae].	38.57	350	207	3	36	385	251	592	6e-73	253
rs:WP_037419974	DNA topoisomerase III, partial [Serratia grimesii].	36.73	373	226	4	36	407	251	614	6e-73	253
rs:WP_042784710	DNA topoisomerase III [Serratia sp. SCBI].	36.55	383	233	4	36	417	251	624	6e-73	253
rs:WP_044344117	DNA topoisomerase III [Pseudomonas meliae].	36.13	382	241	2	36	416	241	620	6e-73	254
tr:Q66AN9_YERPS	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953}; Flags: Precursor;	36.51	367	225	3	36	402	252	610	6e-73	253
rs:WP_041175458	DNA topoisomerase III [Yersinia pseudotuberculosis].	36.51	367	225	3	36	402	251	609	6e-73	253
rs:WP_045401540	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	38.57	350	207	3	36	385	251	592	6e-73	253
rs:WP_040043199	DNA topoisomerase III [Pectobacterium carotovorum].	35.80	405	240	6	36	438	251	637	6e-73	253
rs:WP_002211670	DNA topoisomerase III [Yersinia pestis].	36.51	367	225	3	36	402	251	609	6e-73	253
rs:WP_004248229	DNA topoisomerase III [Proteus mirabilis].	39.60	351	202	4	36	385	251	592	6e-73	253
rs:WP_047364334	DNA topoisomerase III [Enterobacter sp. GN02283].	38.29	350	208	3	36	385	251	592	7e-73	253
rs:WP_001750506	DNA topoisomerase III [Salmonella enterica].	39.30	369	218	4	36	398	242	610	7e-73	254
rs:WP_010385040	DNA topoisomerase III [Pseudoalteromonas rubra].	38.13	375	222	1	35	409	250	614	7e-73	253
rs:WP_041910472	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	38.29	350	208	3	36	385	251	592	7e-73	253
rs:WP_002227932	DNA topoisomerase III [Yersinia pestis].	36.51	367	225	3	36	402	252	610	7e-73	253
rs:WP_041480830	DNA topoisomerase III [Pseudomonas sp. PTA1].	37.46	347	215	1	61	407	267	611	7e-73	253
rs:WP_004250914	DNA topoisomerase III [Proteus mirabilis].	39.60	351	202	4	36	385	251	592	7e-73	253
rs:WP_044616212	DNA topoisomerase III [Gynuella sunshinyii].	34.29	385	250	1	15	399	232	613	7e-73	253
rs:WP_041105535	DNA topoisomerase III [Pseudomonas stutzeri].	38.95	344	208	1	65	408	271	612	7e-73	253
tr:E5B623_ERWAM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	39.32	351	205	3	36	386	251	593	7e-73	253
rs:WP_015276251	DNA topoisomerase III [Pseudomonas stutzeri].	37.73	379	234	2	36	413	241	618	7e-73	253
tr:A0A085IJE3_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	43.20	338	187	3	36	371	242	576	7e-73	253
gp:CP000950_2060	DNA topoisomerase III [Yersinia pseudotuberculosis YPIII]	36.51	367	225	3	36	402	252	610	8e-73	253
rs:WP_012105118	DNA topoisomerase III [Yersinia pseudotuberculosis].	36.51	367	225	3	36	402	251	609	8e-73	253
rs:WP_045288446	DNA topoisomerase III [Pluralibacter gergoviae].	39.03	351	204	4	36	385	251	592	8e-73	253
rs:WP_008606329	DNA topoisomerase III [Alishewanella aestuarii].	38.46	351	215	1	36	385	251	601	8e-73	253
rs:WP_045910241	DNA topoisomerase III [Enterobacter cloacae].	38.29	350	208	3	36	385	251	592	8e-73	253
rs:WP_047742142	DNA topoisomerase III [Enterobacter asburiae].	36.22	392	231	4	36	427	251	623	8e-73	253
rs:WP_022940269	DNA topoisomerase III [Psychromonas hadalis].	37.36	364	217	2	36	399	251	603	8e-73	253
rs:WP_038633249	MULTISPECIES: DNA topoisomerase III [Yersinia].	35.68	384	238	4	36	418	251	626	8e-73	253
rs:WP_005615023	DNA topoisomerase III [Actinobacillus pleuropneumoniae].	37.71	350	210	2	36	385	252	593	8e-73	253
rs:WP_023343916	DNA topoisomerase III [Enterobacter sp. MGH 16].	38.29	350	208	3	36	385	251	592	9e-73	253
gp:CP009997_560	DNA topoisomerase III family protein [Yersinia kristensenii]	35.68	384	238	4	36	418	252	627	9e-73	253
rs:WP_024908566	DNA topoisomerase III [Enterobacter asburiae].	38.29	350	208	3	36	385	251	592	9e-73	253
rs:WP_044327842	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	37.14	350	212	3	36	385	251	592	9e-73	253
rs:WP_023296331	DNA topoisomerase III [Enterobacter cloacae].	38.00	350	209	3	36	385	251	592	1e-72	253
tr:F3GYQ3_PSESX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	36.36	374	235	2	36	408	241	612	1e-72	255
rs:WP_031323200	DNA topoisomerase III [Pseudomonas stutzeri].	38.81	353	215	1	61	413	267	618	1e-72	253
rs:WP_032650922	MULTISPECIES: DNA topoisomerase III [Enterobacter].	38.29	350	208	3	36	385	251	592	1e-72	253
rs:WP_039300069	DNA topoisomerase III [Pectobacterium betavasculorum].	36.05	405	239	6	36	438	251	637	1e-72	253
rs:WP_046620732	DNA topoisomerase III [Pseudomonas stutzeri].	38.68	349	213	1	65	413	271	618	1e-72	253
rs:WP_025383844	DNA topoisomerase III [Yersinia similis].	36.05	380	234	4	36	414	251	622	1e-72	253
rs:WP_047958308	DNA topoisomerase III [Enterobacter sp. BIDMC92].	35.97	392	232	4	36	427	251	623	1e-72	253
rs:WP_045415135	DNA topoisomerase III [Enterobacter asburiae].	38.29	350	208	3	36	385	251	592	1e-72	253
rs:WP_013097044	DNA topoisomerase III [Enterobacter cloacae].	38.29	350	208	3	36	385	251	592	1e-72	253
rs:WP_004157807	DNA topoisomerase III [Erwinia amylovora].	39.32	351	205	3	36	386	251	593	1e-72	253
rs:WP_023335338	DNA topoisomerase III [Enterobacter sp. MGH 24].	38.00	350	209	3	36	385	251	592	1e-72	253
rs:WP_032681222	DNA topoisomerase III [Enterobacter sp. BIDMC 30].	38.00	350	209	3	36	385	251	592	1e-72	252
rs:WP_032907590	DNA topoisomerase III [Yersinia intermedia].	35.49	386	240	4	36	420	251	628	1e-72	253
tr:A0A0E8GRM0_YERIN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CRE40711.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRE40711.1};	35.49	386	240	4	36	420	252	629	1e-72	253
rs:WP_008500701	MULTISPECIES: DNA topoisomerase III [Enterobacter].	38.29	350	208	3	36	385	251	592	1e-72	252
rs:WP_045346457	DNA topoisomerase III [Enterobacter cloacae].	38.29	350	208	3	36	385	251	592	1e-72	252
rs:WP_032910851	DNA topoisomerase III [Yersinia frederiksenii].	36.05	380	234	4	36	414	251	622	1e-72	253
rs:WP_035528896	hypothetical protein, partial [Haliea salexigens].	38.90	365	212	4	32	386	243	606	1e-72	252
rs:WP_006809125	MULTISPECIES: DNA topoisomerase III [Enterobacter].	38.29	350	208	3	36	385	251	592	1e-72	252
rs:WP_015465256	DNA topoisomerase III [Psychromonas sp. CNPT3].	35.14	387	234	4	22	405	243	615	1e-72	252
rs:WP_048278222	DNA topoisomerase III [Pluralibacter gergoviae].	38.57	350	207	3	36	385	251	592	1e-72	253
tr:A0A061JJ33_PSEST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	38.81	353	215	1	61	413	279	630	1e-72	253
rs:WP_048211904	DNA topoisomerase III [Citrobacter freundii].	38.00	350	209	3	36	385	251	592	1e-72	253
rs:WP_008987582	DNA topoisomerase III [Photobacterium leiognathi].	37.91	364	218	3	36	396	251	609	1e-72	253
rs:WP_048282488	DNA topoisomerase III [Pluralibacter gergoviae].	38.57	350	207	3	36	385	251	592	1e-72	253
rs:WP_045406323	DNA topoisomerase III [Enterobacter asburiae].	38.29	350	208	3	36	385	251	592	1e-72	252
rs:WP_004390915	DNA topoisomerase III [Yersinia kristensenii].	36.05	380	234	4	36	414	251	622	1e-72	252
rs:WP_014826201	DNA topoisomerase III [Desulfosporosinus acidiphilus].	36.21	428	253	8	18	435	211	628	1e-72	254
rs:WP_032947018	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	36.91	382	232	4	36	417	251	623	1e-72	253
rs:WP_043084421	DNA topoisomerase III [Pluralibacter gergoviae].	38.57	350	207	3	36	385	251	592	1e-72	252
tr:A4VNK8_PSEU5	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	39.26	349	211	1	65	413	238	585	1e-72	251
rs:WP_005897679	DNA topoisomerase III [Aeromonas molluscorum].	35.79	380	235	2	36	413	249	621	1e-72	253
rs:WP_038705838	DNA topoisomerase III [Pseudomonas mosselii].	40.12	334	198	1	74	407	280	611	2e-72	252
rs:WP_037043705	DNA topoisomerase III [Pseudomonas sp. BAY1663].	36.36	374	236	2	36	408	241	613	2e-72	252
rs:WP_028941765	DNA topoisomerase III [Pseudomonas vranovensis].	38.89	342	207	1	67	408	273	612	2e-72	252
rs:WP_031519835	DNA topoisomerase III [Cronobacter sp. 1383].	36.79	386	227	5	36	413	251	627	2e-72	252
rs:WP_005604263	DNA topoisomerase III [Actinobacillus pleuropneumoniae].	37.71	350	210	2	36	385	252	593	2e-72	252
rs:WP_009875554	DNA topoisomerase III [Actinobacillus pleuropneumoniae].	37.71	350	210	2	36	385	252	593	2e-72	252
rs:WP_005607634	DNA topoisomerase III [Actinobacillus pleuropneumoniae].	37.71	350	210	2	36	385	252	593	2e-72	252
tr:R8X2E9_9ENTR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	36.91	382	232	4	36	417	263	635	2e-72	253
tr:A0A084YU57_9ENTR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	36.73	373	226	4	36	407	251	614	2e-72	253
rs:WP_047717757	DNA topoisomerase III [Enterobacter cloacae].	38.29	350	208	3	36	385	251	592	2e-72	252
rs:WP_005597148	DNA topoisomerase III [Actinobacillus pleuropneumoniae].	37.71	350	210	2	36	385	252	593	2e-72	252
rs:WP_038888133	DNA topoisomerase III [Cronobacter dublinensis].	37.40	369	223	3	36	404	251	611	2e-72	252
rs:WP_032674572	DNA topoisomerase III [Enterobacter cloacae].	38.29	350	208	3	36	385	251	592	2e-72	252
tr:A3N0A8_ACTP2	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.71	350	210	2	36	385	259	600	2e-72	252
rs:WP_038419141	DNA topoisomerase III [Enterobacter cloacae].	38.29	350	208	3	36	385	251	592	2e-72	252
tr:K8B175_9ENTR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.13	369	224	3	36	404	251	611	2e-72	252
rs:WP_038883834	DNA topoisomerase III [Cronobacter dublinensis].	37.13	369	224	3	36	404	251	611	2e-72	252
rs:WP_032651511	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	38.29	350	208	3	36	385	251	592	2e-72	252
tr:F3ET09_PSEA0	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	35.86	382	242	2	36	416	241	620	2e-72	252
rs:WP_011168879	DNA topoisomerase III [Pseudomonas savastanoi].	35.86	382	242	2	36	416	241	620	2e-72	252
rs:WP_009112895	DNA topoisomerase III [Brenneria sp. EniD312].	37.34	383	229	5	36	416	251	624	2e-72	252
rs:WP_048375716	DNA topoisomerase III [Pseudomonas lundensis].	37.22	360	224	1	61	420	267	624	2e-72	252
rs:WP_038640087	DNA topoisomerase III [Citrobacter freundii].	37.71	350	210	3	36	385	251	592	2e-72	252
rs:WP_047051503	DNA topoisomerase III [Enterobacter cloacae].	38.00	350	209	3	36	385	251	592	2e-72	252
rs:WP_038872642	DNA topoisomerase III [Cronobacter dublinensis].	37.40	369	223	3	36	404	251	611	2e-72	252
rs:WP_019018703	DNA topoisomerase III [Halomonas lutea].	35.59	413	248	4	30	435	237	638	2e-72	252
rs:WP_044342681	DNA topoisomerase III [Pseudomonas oryzihabitans].	35.37	410	247	5	32	428	257	661	2e-72	255
tr:I6HGX2_SHIFL	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.71	350	210	3	36	385	251	592	2e-72	252
rs:WP_009637991	DNA topoisomerase III [Serratia sp. M24T3].	37.37	372	225	3	36	407	251	614	2e-72	252
rs:WP_006174820	DNA topoisomerase III [Enterobacter cancerogenus].	37.71	350	210	3	36	385	251	592	2e-72	252
rs:WP_009408843	DNA topoisomerase III [Pseudomonas putida].	38.66	344	209	1	65	408	271	612	2e-72	252
tr:A0A0A7S2M8_9GAMM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	36.22	370	232	1	36	405	257	622	2e-72	251
rs:WP_044712175	DNA topoisomerase III [Citrobacter freundii].	37.71	350	210	3	36	385	251	592	2e-72	252
rs:WP_020306940	DNA topoisomerase III [Pseudomonas stutzeri].	38.68	349	213	1	65	413	271	618	2e-72	252
rs:WP_010557793	DNA topoisomerase III [Pseudoalteromonas marina].	38.57	350	206	1	36	385	251	591	2e-72	252
rs:WP_015957841	DNA topoisomerase III [Clostridium botulinum].	38.57	350	211	3	46	391	242	591	2e-72	254
rs:WP_040133203	DNA topoisomerase III [Providencia stuartii].	39.94	348	200	4	36	382	251	590	2e-72	252
rs:WP_011093894	DNA topoisomerase III [Pectobacterium atrosepticum].	35.80	405	240	6	36	438	251	637	2e-72	252
tr:A0A023VCL4_CITFR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.71	350	210	3	36	385	263	604	2e-72	252
rs:WP_041755624	DNA topoisomerase III [Pseudomonas stutzeri].	39.26	349	211	1	65	413	271	618	2e-72	252
rs:WP_032639806	DNA topoisomerase III [Enterobacter cloacae].	38.00	350	209	3	36	385	251	592	2e-72	251
rs:WP_045327023	DNA topoisomerase III [Enterobacter asburiae].	38.00	350	209	3	36	385	251	592	2e-72	251
rs:WP_047761825	DNA topoisomerase III [Neisseria sp. KH1503].	38.69	367	213	4	36	396	211	571	2e-72	251
gp:CP007371_1649	DNA topoisomerase III [Salmonella enterica subsp. enterica serovar Enteritidis str.]	37.71	350	210	3	36	385	251	592	2e-72	252
rs:WP_019076618	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	36.91	382	232	4	36	417	251	623	3e-72	252
rs:WP_044319251	DNA topoisomerase III [Pseudomonas amygdali].	35.86	382	242	2	36	416	241	620	3e-72	252
rs:WP_032941785	DNA topoisomerase III [Citrobacter sp. 30_2].	37.71	350	210	3	36	385	251	592	3e-72	252
rs:WP_047723679	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	38.00	350	209	3	36	385	251	592	3e-72	251
rs:WP_032943124	DNA topoisomerase III [Citrobacter freundii].	37.71	350	210	3	36	385	251	592	3e-72	251
rs:WP_043016627	DNA topoisomerase III [Citrobacter freundii].	37.71	350	210	3	36	385	251	592	3e-72	251
rs:WP_005779714	DNA topoisomerase III [Pseudomonas amygdali].	35.86	382	242	2	36	416	241	620	3e-72	252
rs:WP_032949103	DNA topoisomerase III [Citrobacter freundii].	37.71	350	210	3	36	385	251	592	3e-72	251
rs:WP_032936119	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	36.16	401	245	4	36	436	251	640	3e-72	251
tr:A0A064E136_CITFR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.71	350	210	3	36	385	263	604	3e-72	252
rs:WP_044700023	DNA topoisomerase III [Citrobacter freundii].	37.71	350	210	3	36	385	251	592	3e-72	251
rs:WP_003846640	MULTISPECIES: DNA topoisomerase III [Citrobacter].	37.71	350	210	3	36	385	251	592	3e-72	251
rs:WP_038275861	DNA topoisomerase III [Yersinia ruckeri].	36.76	370	224	4	36	404	251	611	3e-72	251
rs:WP_032934436	DNA topoisomerase III [Citrobacter freundii].	37.71	350	210	3	36	385	251	592	3e-72	251
rs:WP_048216538	DNA topoisomerase III [Citrobacter freundii].	37.71	350	210	3	36	385	251	592	3e-72	251
gp:AE017042_1901	DNA topoisomerase III [Yersinia pestis biovar Microtus str. 91001]	36.51	367	225	3	36	402	252	610	3e-72	251
rs:WP_002230887	DNA topoisomerase III [Yersinia pestis].	36.51	367	225	3	36	402	251	609	3e-72	251
tr:X7HRM9_CITFR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.71	350	210	3	36	385	263	604	3e-72	252
rs:WP_047368337	DNA topoisomerase III [Enterobacter sp. GN02548].	38.00	350	209	3	36	385	251	592	3e-72	251
rs:WP_003030667	MULTISPECIES: DNA topoisomerase III [Citrobacter].	37.71	350	210	3	36	385	251	592	3e-72	251
rs:WP_016775107	DNA topoisomerase III, partial [Pseudomonas sp. R62].	38.39	336	205	1	61	396	267	600	3e-72	250
rs:WP_034934415	DNA topoisomerase III [Erwinia mallotivora].	34.74	426	264	5	36	459	242	655	3e-72	252
rs:WP_032663739	DNA topoisomerase III [Enterobacter cloacae].	38.29	350	208	3	36	385	251	592	4e-72	251
rs:WP_032814471	DNA topoisomerase III [Yersinia mollaretii].	35.86	382	234	4	36	414	251	624	4e-72	251
rs:WP_044652667	DNA topoisomerase III, partial [Klebsiella variicola].	38.58	337	197	4	50	385	1	328	4e-72	244
tr:C4SCV1_YERMO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	35.86	382	234	4	36	414	252	625	4e-72	251
tr:X7I8G3_CITFR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.71	350	210	3	36	385	263	604	4e-72	251
rs:WP_045261603	DNA topoisomerase III [Enterobacter sp. 35669].	38.00	350	209	3	36	385	251	592	4e-72	251
rs:WP_040233658	DNA topoisomerase III [Citrobacter sp. CIP 55.13].	37.71	350	210	3	36	385	251	592	4e-72	251
rs:WP_035528736	hypothetical protein, partial [Haliea salexigens].	35.80	405	248	5	35	427	246	650	4e-72	251
rs:WP_045285254	DNA topoisomerase III [Enterobacter sp. 35699].	35.71	392	233	4	36	427	251	623	4e-72	251
rs:WP_045630122	DNA topoisomerase III [Enterobacter cloacae].	38.00	350	209	3	36	385	251	592	4e-72	251
rs:WP_005744254	DNA topoisomerase III [Pseudomonas amygdali].	35.86	382	242	2	36	416	241	620	4e-72	251
rs:WP_039266154	DNA topoisomerase III [Enterobacter sp. FB].	38.29	350	208	3	36	385	251	592	4e-72	251
rs:WP_026739409	DNA topoisomerase III [Lonsdalea quercina].	35.53	380	237	3	36	414	251	623	4e-72	251
rs:WP_025757378	DNA topoisomerase III [Enterobacter cloacae].	35.71	392	233	4	36	427	251	623	4e-72	251
rs:WP_047294473	DNA topoisomerase III [Pseudomonas fluorescens].	37.22	360	224	1	61	420	267	624	4e-72	251
rs:WP_036940411	DNA topoisomerase III [Providencia stuartii].	39.94	348	200	4	36	382	251	590	5e-72	251
rs:WP_004920303	DNA topoisomerase III [Providencia stuartii].	39.94	348	200	4	36	382	251	590	5e-72	251
rs:WP_014656070	DNA topoisomerase III [Providencia stuartii].	39.94	348	200	4	36	382	251	590	5e-72	251
rs:WP_039106785	DNA topoisomerase III, partial [Frischella perrara].	36.64	363	226	1	36	398	257	615	5e-72	250
rs:WP_045336155	DNA topoisomerase III [Enterobacter asburiae].	38.00	350	209	3	36	385	251	592	5e-72	251
rs:WP_046857838	DNA topoisomerase III [Pseudomonas sp. CCOS 191].	39.30	341	205	1	67	407	273	611	5e-72	251
rs:WP_047282777	DNA topoisomerase III [Pseudomonas fluorescens].	37.22	360	224	1	61	420	267	624	5e-72	251
rs:WP_023444430	DNA topoisomerase III [Pseudomonas chloritidismutans].	38.40	349	214	1	65	413	271	618	5e-72	251
rs:WP_024689379	DNA topoisomerase III [Pseudomonas syringae].	35.56	374	238	2	36	408	241	612	5e-72	251
rs:WP_047280872	DNA topoisomerase III [Pseudomonas fluorescens].	37.22	360	224	1	61	420	267	624	5e-72	251
rs:WP_035477107	DNA topoisomerase III [Aliagarivorans taiwanensis].	37.54	357	214	2	36	386	251	604	5e-72	251
rs:WP_005732953	DNA topoisomerase III [Pseudomonas amygdali].	37.36	356	221	1	61	416	267	620	6e-72	251
rs:WP_006684866	DNA topoisomerase III [Citrobacter youngae].	37.43	350	211	3	36	385	251	592	6e-72	251
rs:WP_017217778	MULTISPECIES: DNA topoisomerase III [Pseudoalteromonas].	37.61	351	210	1	35	385	250	591	6e-72	251
rs:WP_016599634	DNA topoisomerase III, partial [Yersinia pestis].	38.42	341	202	3	36	376	251	583	6e-72	249
rs:WP_025809837	DNA topoisomerase III [Pseudomonas chlororaphis].	33.95	430	263	6	36	458	241	656	6e-72	251
rs:WP_019210140	DNA topoisomerase III [Yersinia massiliensis].	35.86	382	234	4	36	414	251	624	6e-72	251
rs:WP_016680565	DNA topoisomerase III, partial [Yersinia pestis].	38.42	341	202	3	36	376	251	583	7e-72	249
rs:WP_018403339	DNA topoisomerase III [Marinobacter lipolyticus].	34.59	477	252	7	32	459	254	719	7e-72	252
rs:XP_011566445	PREDICTED: DNA topoisomerase 3-like [Plutella xylostella].	37.07	375	226	4	36	409	251	616	7e-72	251
rs:WP_046275888	DNA topoisomerase III [Citrobacter amalonaticus].	36.65	382	233	4	36	417	251	623	7e-72	251
rs:WP_039198970	DNA topoisomerase III [Actinobacillus equuli].	37.61	351	211	2	36	386	252	594	7e-72	250
rs:WP_024695632	DNA topoisomerase III [Pseudomonas syringae].	35.56	374	238	2	36	408	241	612	7e-72	251
rs:WP_045338920	DNA topoisomerase III [Enterobacter cloacae].	38.00	350	209	3	36	385	251	592	7e-72	250
tr:C5S0M3_9PAST	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.43	358	214	3	36	393	266	613	8e-72	250
rs:WP_042308879	DNA topoisomerase III [Citrobacter werkmanii].	37.43	350	211	3	36	385	251	592	8e-72	250
rs:WP_044321692	DNA topoisomerase III [Pseudomonas amygdali].	35.86	382	242	2	36	416	241	620	8e-72	251
rs:WP_026313232	DNA topoisomerase III [Actinobacillus capsulatus].	37.22	352	213	2	36	387	252	595	8e-72	250
rs:WP_014903894	DNA topoisomerase III [Desulfosporosinus meridiei].	37.35	407	240	6	36	435	230	628	8e-72	252
rs:WP_016596683	DNA topoisomerase III, partial [Yersinia pestis].	38.42	341	202	3	36	376	251	583	8e-72	249
rs:WP_011219248	DNA topoisomerase III [Photobacterium profundum].	37.39	353	218	2	36	385	251	603	8e-72	250
rs:WP_002553877	DNA topoisomerase III [Pseudomonas savastanoi].	37.36	356	221	1	61	416	267	620	8e-72	251
rs:WP_010607879	DNA topoisomerase III [Pseudoalteromonas flavipulchra].	37.61	351	210	1	35	385	250	591	8e-72	250
rs:WP_040214331	DNA topoisomerase III [Clostridium sp. MS1].	38.84	363	208	4	41	396	237	592	8e-72	252
rs:WP_035596778	DNA topoisomerase III [Halomonas salina].	36.20	384	232	2	35	416	242	614	8e-72	251
rs:WP_032627286	DNA topoisomerase III [Pseudomonas syringae].	38.24	353	214	2	65	417	271	619	8e-72	250
rs:WP_045989685	DNA topoisomerase III [Pseudoalteromonas piscicida].	37.61	351	210	1	35	385	250	591	9e-72	250
rs:WP_036936365	DNA topoisomerase III [Proteus vulgaris].	38.29	350	208	3	36	385	251	592	9e-72	250
rs:WP_045269436	DNA topoisomerase III [Enterobacter sp. 35730].	36.39	393	229	5	36	427	251	623	9e-72	250
rs:WP_035293839	DNA topoisomerase III [Actinobacillus minor].	37.43	358	214	3	36	393	252	599	9e-72	250
rs:WP_042125997	DNA topoisomerase III [Pseudomonas japonica].	36.72	384	233	4	61	436	267	648	9e-72	250
rs:WP_045135044	DNA topoisomerase III [Enterobacter cloacae].	36.39	393	229	5	36	427	251	623	9e-72	250
rs:WP_039492215	DNA topoisomerase III [Pseudoalteromonas elyakovii].	37.61	351	210	1	35	385	250	591	9e-72	250
rs:WP_004665587	DNA topoisomerase III [Pseudomonas savastanoi].	35.60	382	243	2	36	416	241	620	1e-71	250
rs:WP_032636920	DNA topoisomerase III [Enterobacter cloacae].	36.39	393	229	5	36	427	251	623	1e-71	250
rs:WP_042039942	DNA topoisomerase III [Aeromonas rivuli].	35.79	380	235	2	36	413	249	621	1e-71	250
rs:WP_014883454	MULTISPECIES: DNA topoisomerase III [Enterobacter].	36.39	393	229	5	36	427	251	623	1e-71	250
rs:WP_011793734	DNA topoisomerase III [Acidovorax citrulli].	35.62	393	237	4	67	452	273	656	1e-71	251
rs:WP_042392964	DNA topoisomerase III [Escherichia vulneris].	35.71	406	235	6	36	435	251	636	1e-71	250
rs:WP_047256201	DNA topoisomerase III [Moellerella wisconsensis].	38.29	350	208	3	36	385	251	592	1e-71	250
rs:WP_042569714	DNA topoisomerase III [Yersinia intermedia].	35.23	386	241	4	36	420	251	628	1e-71	250
rs:WP_047012732	DNA topoisomerase III [Spongiibacter sp. IMCC21906].	35.48	420	260	6	36	454	241	650	1e-71	250
rs:WP_047027173	DNA topoisomerase III [Enterobacter sp. GN02186].	38.46	351	206	4	36	385	251	592	1e-71	250
rs:WP_045726250	DNA topoisomerase III [Clostridium baratii].	37.41	401	239	4	36	434	231	621	1e-71	251
tr:F3C4Q0_PSESG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	35.60	382	243	2	36	416	241	620	1e-71	250
rs:WP_008712616	DNA topoisomerase III [Synergistes sp. 3_1_syn1].	34.21	418	266	5	29	445	238	647	2e-71	251
rs:WP_025993493	DNA topoisomerase III [Pseudomonas viridiflava].	37.07	348	217	1	61	408	267	612	2e-71	250
rs:WP_045861762	hypothetical protein [Alteromonadaceae bacterium Bs12].	35.24	437	252	7	36	457	245	665	2e-71	251
rs:WP_021820845	DNA topoisomerase III [Halomonas huangheensis].	37.40	361	212	3	35	392	242	591	2e-71	250
rs:WP_043305647	DNA topoisomerase III [Pseudomonas viridiflava].	37.07	348	217	1	61	408	267	612	2e-71	249
rs:WP_038669482	DNA topoisomerase III, partial [Sodalis praecaptivus].	38.46	351	206	4	36	385	251	592	2e-71	249
rs:WP_028012778	DNA topoisomerase III [Enterobacter cloacae].	38.18	351	207	4	36	385	251	592	2e-71	249
rs:WP_045980530	DNA topoisomerase III [Pseudoalteromonas ruthenica].	37.43	366	219	3	36	401	251	606	2e-71	249
rs:WP_004886535	DNA topoisomerase III [Pseudomonas viridiflava].	37.07	348	217	1	61	408	267	612	2e-71	249
rs:WP_023332748	MULTISPECIES: DNA topoisomerase III [Enterobacter].	36.13	393	230	5	36	427	251	623	2e-71	249
rs:WP_016981353	DNA topoisomerase III [Pseudomonas amygdali].	35.60	382	243	2	36	416	241	620	2e-71	249
rs:WP_040241313	DNA topoisomerase III, partial [Xanthomonas citri].	34.89	407	244	5	36	431	241	637	2e-71	249
tr:W0HXD6_9ENTR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.46	351	206	4	36	385	251	592	3e-71	249
rs:WP_014991412	DNA topoisomerase III [Actinobacillus suis].	37.43	350	211	2	36	385	252	593	3e-71	249
rs:WP_042815526	DNA topoisomerase III, partial [Xanthomonas citri].	34.89	407	244	5	36	431	241	637	3e-71	249
rs:WP_006658753	DNA topoisomerase III [Providencia alcalifaciens].	37.71	350	210	3	36	385	251	592	3e-71	249
rs:WP_047275872	DNA topoisomerase III [Pseudomonas fluorescens].	37.57	346	214	1	61	406	267	610	3e-71	249
rs:WP_045442006	MULTISPECIES: DNA topoisomerase III [Citrobacter].	37.14	350	212	3	36	385	251	592	3e-71	249
rs:WP_007159931	DNA topoisomerase III [Pseudomonas psychrotolerans].	38.67	375	225	3	36	408	241	612	3e-71	249
rs:WP_027335540	DNA topoisomerase III [Halomonas sp. HL-48].	35.82	402	235	4	35	435	242	621	3e-71	249
rs:WP_022943541	DNA topoisomerase III [Pseudoalteromonas ruthenica].	37.70	366	218	3	36	401	251	606	3e-71	249
rs:WP_045923569	DNA topoisomerase III [Clostridium tetani].	36.71	365	217	4	36	391	230	589	4e-71	250
rs:WP_047276194	DNA topoisomerase III [Pseudomonas fluorescens].	37.57	346	214	1	61	406	267	610	4e-71	249
rs:WP_039260585	DNA topoisomerase III [Clostridium tetani].	36.71	365	217	4	36	391	230	589	4e-71	250
rs:WP_032638381	DNA topoisomerase III [Enterobacter sp. EGD-HP1].	37.71	350	210	3	36	385	251	592	4e-71	248
rs:WP_033872262	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	36.56	372	227	4	36	403	241	607	4e-71	248
rs:WP_011533418	DNA topoisomerase III [Pseudomonas entomophila].	37.87	375	224	3	36	406	241	610	4e-71	249
rs:WP_047716225	DNA topoisomerase III [Enterobacter asburiae].	37.71	350	210	3	36	385	251	592	4e-71	248
rs:WP_039989635	DNA topoisomerase III, partial [Paraglaciecola arctica].	38.44	372	221	4	35	401	250	618	4e-71	248
rs:WP_023437240	DNA topoisomerase III [Clostridium tetani].	36.71	365	217	4	36	391	231	590	4e-71	250
rs:WP_047810113	DNA topoisomerase III [Desulfosporosinus acididurans].	35.03	431	264	4	11	435	207	627	4e-71	250
rs:WP_045377142	hypothetical protein [Enterobacter aerogenes].	34.35	428	264	6	35	459	250	663	4e-71	249
rs:WP_044323396	DNA topoisomerase III [Pseudomonas amygdali].	37.08	356	222	1	61	416	267	620	5e-71	249
rs:WP_006708809	DNA topoisomerase III [Serratia symbiotica].	37.01	354	215	3	32	385	247	592	5e-71	248
rs:WP_012017079	DNA topoisomerase III [Enterobacter sp. 638].	36.31	369	227	3	36	404	251	611	5e-71	248
rs:WP_004254081	DNA topoisomerase III [Providencia rettgeri].	38.00	350	209	3	36	385	251	592	5e-71	248
rs:WP_029838760	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	42.16	287	159	1	36	322	255	534	5e-71	246
rs:WP_033873175	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	36.84	361	220	3	36	392	241	597	6e-71	247
rs:WP_004095637	DNA topoisomerase III, partial [Acetonema longum].	36.17	423	239	10	30	442	239	640	6e-71	248
tr:K6Z8H7_9ALTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	38.44	372	221	4	35	401	250	618	6e-71	248
rs:WP_017876401	hypothetical protein [Janthinobacterium sp. CG3].	37.01	462	245	9	30	452	240	694	6e-71	249
rs:WP_045492462	DNA topoisomerase III [Pseudomonas sp. StFLB209].	36.53	375	235	2	60	433	266	638	6e-71	248
rs:WP_043190411	DNA topoisomerase III [Pseudomonas rhizosphaerae].	38.11	349	214	1	60	408	266	612	6e-71	248
rs:WP_029243501	DNA topoisomerase III [Pseudomonas viridiflava].	37.07	348	217	1	61	408	267	612	7e-71	248
rs:WP_036965804	DNA topoisomerase III [Providencia alcalifaciens].	37.71	350	210	3	36	385	251	592	7e-71	248
rs:WP_046010027	DNA topoisomerase III [Oleispira antarctica].	35.89	418	250	6	36	436	255	671	7e-71	248
rs:WP_034070008	DNA topoisomerase III [Pseudomonas aeruginosa].	36.08	449	264	6	1	430	205	649	7e-71	249
rs:WP_013332057	DNA topoisomerase III [Halomonas elongata].	36.29	394	236	2	21	414	232	610	7e-71	248
rs:WP_034443475	hypothetical protein [Cloacibacillus evryensis].	33.97	418	267	5	29	445	238	647	7e-71	249
rs:WP_001895995	DNA topoisomerase III, partial [Vibrio cholerae].	41.37	307	173	1	79	385	1	300	7e-71	240
rs:WP_039315510	DNA topoisomerase III [Clostridium baratii].	37.16	401	240	4	36	434	231	621	7e-71	249
rs:WP_014520434	DNA topoisomerase III [Clostridium botulinum].	38.00	350	213	3	46	391	242	591	8e-71	249
rs:WP_036972697	DNA topoisomerase III, partial [Providencia alcalifaciens].	37.71	350	210	3	36	385	154	495	8e-71	245
rs:WP_003356144	DNA topoisomerase III [Clostridium botulinum].	38.75	351	209	4	46	391	242	591	8e-71	249
rs:WP_039607059	DNA topoisomerase III, partial [Pseudomonas tuomuerensis].	35.73	375	239	2	35	407	240	614	8e-71	247
rs:WP_006812878	DNA topoisomerase III [Providencia rustigianii].	38.00	350	209	3	36	385	251	592	8e-71	248
rs:WP_019742482	DNA topoisomerase III [Pseudomonas savastanoi].	35.34	382	244	2	36	416	241	620	8e-71	248
rs:WP_036975663	DNA topoisomerase III [Providencia alcalifaciens].	37.71	350	210	3	36	385	251	592	8e-71	248
rs:WP_036963785	DNA topoisomerase III [Providencia alcalifaciens].	37.71	350	210	3	36	385	251	592	9e-71	248
rs:WP_034599166	DNA topoisomerase III [Desulfosporosinus sp. HMP52].	36.41	401	242	5	40	435	236	628	9e-71	249
rs:WP_048214356	DNA topoisomerase III [Citrobacter freundii].	37.43	350	211	3	36	385	251	592	9e-71	248
rs:WP_040266123	DNA topoisomerase III [Serratia symbiotica].	37.08	356	212	4	32	385	247	592	1e-70	247
rs:WP_003286333	DNA topoisomerase III [Pseudomonas stutzeri].	37.47	387	239	2	23	408	231	615	1e-70	248
rs:WP_033946171	DNA topoisomerase III [Pseudomonas aeruginosa].	34.39	442	263	8	33	459	238	667	1e-70	249
rs:WP_036770428	DNA topoisomerase III, partial [Plesiomonas shigelloides].	37.30	370	219	5	22	389	240	598	1e-70	247
rs:WP_033065324	DNA topoisomerase III [Clostridium botulinum].	37.71	350	214	3	46	391	242	591	1e-70	249
rs:WP_042545975	DNA topoisomerase III [Yersinia aldovae].	37.43	350	211	3	36	385	251	592	1e-70	247
rs:WP_035170845	hypothetical protein [Campylobacter fetus].	33.02	424	264	6	35	449	239	651	1e-70	248
rs:WP_048384777	DNA topoisomerase III [Marinobacter psychrophilus].	34.38	477	253	7	32	459	250	715	1e-70	249
rs:WP_047708823	DNA topoisomerase III, partial [Plesiomonas sp. ZOR0011].	37.30	370	219	5	22	389	240	598	1e-70	247
tr:C4U453_YERAL	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.43	350	211	3	36	385	252	593	1e-70	247
rs:WP_028692401	DNA topoisomerase III [Pseudomonas mosselii].	39.30	341	205	1	67	407	273	611	1e-70	247
rs:WP_041028003	DNA topoisomerase III, partial [Salmonella enterica].	39.87	316	182	3	36	351	251	558	1e-70	245
rs:WP_011098708	DNA topoisomerase III [Clostridium tetani].	36.71	365	217	4	36	391	230	589	1e-70	249
rs:WP_044024448	DNA topoisomerase III [Actinobacillus ureae].	37.43	350	211	2	36	385	252	593	1e-70	247
rs:WP_035111043	DNA topoisomerase III [Clostridium tetani].	36.71	365	217	4	36	391	230	589	1e-70	249
rs:WP_039045709	DNA topoisomerase III, partial [Plesiomonas shigelloides].	37.30	370	219	5	22	389	240	598	2e-70	247
rs:WP_042839186	DNA topoisomerase III [Yersinia aldovae].	37.43	350	211	3	36	385	251	592	2e-70	247
rs:WP_006819591	DNA topoisomerase III [Yokenella regensburgei].	38.07	352	206	4	36	385	251	592	2e-70	247
rs:WP_010628045	DNA topoisomerase III [Halomonas sp. KM-1].	36.66	371	224	1	31	401	238	597	2e-70	247
tr:E8KHI4_9PAST	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.43	350	211	2	36	385	259	600	2e-70	247
rs:WP_038486864	DNA topoisomerase III, partial [Halomonas campaniensis].	38.19	343	199	3	35	376	61	391	2e-70	242
rs:WP_019741001	DNA topoisomerase III [Pseudomonas savastanoi].	35.21	443	256	8	33	459	240	667	2e-70	248
tr:R8ANU3_PLESH	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.30	370	219	5	22	389	240	598	2e-70	248
rs:WP_024612236	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	39.43	350	203	2	36	385	251	591	2e-70	247
rs:WP_012344773	DNA topoisomerase III [Clostridium botulinum].	37.71	350	214	3	46	391	242	591	2e-70	248
rs:WP_029812642	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	41.81	287	160	1	36	322	255	534	2e-70	244
rs:WP_038258043	DNA topoisomerase III [Yokenella regensburgei].	38.07	352	206	4	36	385	251	592	2e-70	246
rs:WP_036979414	DNA topoisomerase III [Providencia alcalifaciens].	37.43	350	211	3	36	385	251	592	2e-70	246
rs:WP_016569421	DNA topoisomerase III [Pseudomonas syringae].	35.21	443	256	8	33	459	240	667	2e-70	248
rs:WP_044427899	DNA topoisomerase III [Mannheimia haemolytica].	33.88	425	214	7	35	457	244	603	3e-70	246
rs:WP_006704071	DNA topoisomerase III [Candidatus Regiella insecticola].	35.71	364	223	4	22	385	240	592	3e-70	246
rs:WP_001701798	DNA topoisomerase III, partial [Salmonella enterica].	38.82	322	189	3	64	385	1	314	3e-70	239
tr:V1FMZ2_SALCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.56	438	274	5	23	459	236	657	3e-70	247
rs:WP_047039718	DNA topoisomerase III [Enterobacter aerogenes].	37.06	367	225	2	31	396	234	595	3e-70	245
rs:WP_020313368	DNA topoisomerase III [Pseudomonas syringae].	37.08	383	224	5	36	404	244	623	3e-70	248
rs:WP_034073868	DNA topoisomerase III [Pseudomonas aeruginosa].	33.63	446	268	7	31	459	236	670	3e-70	248
rs:WP_038414121	DNA topoisomerase III [Pseudomonas cremoricolorata].	38.01	342	210	1	67	408	273	612	3e-70	246
rs:WP_045539505	DNA topoisomerase III [Clostridium botulinum].	37.43	366	213	5	37	391	231	591	3e-70	248
rs:WP_028693701	DNA topoisomerase III [Pseudomonas cremoricolorata].	37.72	342	211	1	67	408	273	612	4e-70	246
rs:WP_010370844	DNA topoisomerase III [Pseudoalteromonas piscicida].	37.04	351	212	1	35	385	250	591	4e-70	246
rs:WP_011948909	DNA topoisomerase III [Clostridium botulinum].	37.43	366	213	5	37	391	231	591	4e-70	248
rs:WP_042843630	DNA topoisomerase III [Providencia rettgeri].	38.00	350	209	3	36	385	251	592	4e-70	246
rs:WP_043526606	DNA topoisomerase III [Halomonas xinjiangensis].	35.97	367	224	1	35	401	242	597	4e-70	246
rs:WP_046835606	DNA topoisomerase III, partial [Pseudomonas amygdali].	39.88	326	190	4	31	353	41	363	4e-70	238
rs:WP_015062325	DNA topoisomerase III [Salmonella sp. 40].	33.33	438	275	5	23	459	236	657	5e-70	246
rs:WP_020303949	hypothetical protein [Pseudomonas syringae].	36.14	415	244	5	33	432	240	648	5e-70	247
rs:WP_027961016	DNA topoisomerase III [Halomonas halodenitrificans].	36.46	384	229	2	35	414	242	614	5e-70	246
rs:WP_045895139	DNA topoisomerase III [Clostridium botulinum].	37.71	350	214	3	46	391	242	591	5e-70	247
rs:WP_034165111	MULTISPECIES: DNA topoisomerase III [Edwardsiella].	39.14	350	205	3	36	385	251	592	5e-70	245
rs:WP_026287158	hypothetical protein [Gilvimarinus chinensis].	34.71	484	252	9	36	459	245	724	5e-70	247
rs:WP_047402736	DNA topoisomerase III [Clostridium botulinum].	38.03	355	206	4	46	391	242	591	7e-70	247
rs:WP_021015936	DNA topoisomerase III [Serratia sp. ATCC 39006].	36.13	382	235	4	36	416	251	624	7e-70	245
rs:WP_046235799	DNA topoisomerase III [Pseudomonas syringae pv. coryli].	34.99	443	257	8	33	459	240	667	7e-70	246
rs:WP_041349811	DNA topoisomerase III [Clostridium botulinum].	38.03	355	206	4	46	391	242	591	7e-70	247
rs:WP_004911175	DNA topoisomerase III [Providencia rettgeri].	38.00	350	209	3	36	385	251	592	8e-70	245
rs:WP_017642366	DNA topoisomerase III [Pseudomonas sp. 313].	38.93	375	224	3	36	408	241	612	8e-70	245
rs:WP_029452668	DNA topoisomerase III [Clostridium algidicarnis].	37.44	390	229	7	41	425	237	616	8e-70	247
rs:WP_024639859	DNA topoisomerase III [Pseudomonas syringae].	35.21	443	256	8	33	459	240	667	9e-70	246
rs:WP_038267162	DNA topoisomerase III [Xenorhabdus cabanillasii].	32.10	458	284	8	12	459	154	594	9e-70	246
rs:WP_007349726	DNA topoisomerase III [Marinobacter sp. ELB17].	34.38	477	253	7	32	459	254	719	9e-70	246
rs:WP_011770752	DNA topoisomerase III [Psychromonas ingrahamii].	35.99	364	222	2	36	399	254	606	1e-69	245
rs:WP_025391090	DNA topoisomerase III [Pseudomonas syringae].	35.90	415	245	5	33	432	240	648	1e-69	246
rs:WP_011152917	hypothetical protein [Pseudomonas syringae].	35.90	415	245	5	33	432	240	648	1e-69	246
rs:WP_008956693	DNA topoisomerase III [Halomonas sp. HAL1].	35.06	405	236	5	35	438	242	620	1e-69	244
rs:WP_036956485	DNA topoisomerase III [Providencia alcalifaciens].	35.42	384	235	5	36	417	251	623	1e-69	244
rs:WP_012704744	DNA topoisomerase III [Clostridium botulinum].	37.75	355	207	4	46	391	242	591	1e-69	246
rs:WP_047757361	DNA topoisomerase III [Providencia rettgeri].	37.71	350	210	3	36	385	251	592	1e-69	244
rs:WP_024933838	DNA topoisomerase III [Clostridium botulinum].	37.75	355	207	4	46	391	242	591	1e-69	246
rs:WP_001727078	DNA topoisomerase III, partial [Salmonella enterica].	39.37	315	183	3	71	385	2	308	1e-69	237
rs:WP_027597366	DNA topoisomerase III [Pseudomonas sp. MOIL14HWK12:I2].	39.66	348	208	1	61	408	267	612	1e-69	244
rs:WP_039178370	DNA topoisomerase III [Halomonas hydrothermalis].	36.10	385	229	4	35	414	241	613	1e-69	245
rs:WP_047227795	DNA topoisomerase III [Pseudomonas brassicacearum].	36.65	382	234	3	61	436	267	646	1e-69	244
rs:WP_023564812	DNA topoisomerase III, partial [Escherichia coli].	40.45	309	176	3	36	344	251	551	1e-69	242
rs:WP_011988143	DNA topoisomerase III [Clostridium botulinum].	37.75	355	207	4	46	391	242	591	1e-69	246
rs:WP_005782553	MULTISPECIES: DNA topoisomerase III [Pseudomonas syringae group].	35.21	443	256	8	33	459	240	667	2e-69	246
rs:WP_030072583	DNA topoisomerase III [Halomonas alkaliantarctica].	38.48	343	198	3	35	376	242	572	2e-69	244
rs:WP_039490448	MULTISPECIES: DNA topoisomerase III [Pseudoalteromonas].	38.29	350	207	1	36	385	251	591	2e-69	244
rs:WP_028303988	DNA topoisomerase III [Oceanospirillum maris].	35.60	382	232	3	32	410	267	637	2e-69	244
rs:WP_033981023	DNA topoisomerase III [Pseudomonas aeruginosa].	33.63	446	268	7	31	459	236	670	2e-69	246
rs:WP_003362991	DNA topoisomerase III [Clostridium botulinum].	38.03	355	206	4	46	391	242	591	2e-69	246
rs:WP_031598161	DNA topoisomerase III [Pseudomonas savastanoi].	34.99	443	257	8	33	459	240	667	2e-69	245
rs:WP_009624172	DNA topoisomerase III [Desulfosporosinus sp. OT].	37.50	408	234	5	36	435	232	626	2e-69	245
rs:WP_045994243	DNA topoisomerase III [Halomonas sp. S2151].	35.61	410	244	3	35	435	242	640	2e-69	244
rs:WP_042394020	DNA topoisomerase III [Clostridium sp. JCC].	35.00	400	240	5	36	428	232	618	2e-69	245
rs:WP_013238995	MULTISPECIES: DNA topoisomerase III [Clostridium].	38.81	353	212	3	43	391	239	591	2e-69	245
rs:WP_042134694	DNA topoisomerase III [Pseudomonas oryzihabitans].	37.93	377	232	1	61	437	267	641	2e-69	244
rs:WP_033951578	DNA topoisomerase III [Pseudomonas aeruginosa].	33.63	446	268	7	31	459	236	670	2e-69	245
rs:WP_012720525	DNA topoisomerase III [Clostridium botulinum].	38.03	355	206	4	46	391	242	591	2e-69	245
rs:WP_024932262	DNA topoisomerase III, partial [Clostridium botulinum].	38.03	355	206	4	46	391	242	591	2e-69	245
rs:WP_021804264	DNA topoisomerase III [Clostridium intestinale].	35.59	399	234	6	36	425	232	616	3e-69	245
rs:WP_011191426	DNA topoisomerase III [Yersinia pseudotuberculosis].	37.17	374	225	3	33	396	239	612	3e-69	245
rs:WP_038485011	DNA topoisomerase III [Halomonas campaniensis].	38.48	343	198	3	35	376	242	572	3e-69	244
rs:WP_027600619	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	39.37	348	209	1	61	408	267	612	3e-69	244
rs:WP_044727381	DNA topoisomerase III [Pseudomonas aeruginosa].	33.63	446	268	7	31	459	236	670	3e-69	245
rs:WP_034020521	DNA topoisomerase III [Pseudomonas aeruginosa].	33.63	446	268	7	31	459	236	670	3e-69	245
rs:WP_009099470	DNA topoisomerase III [Halomonas sp. GFAJ-1].	38.19	343	199	3	35	376	242	572	4e-69	243
rs:WP_028293801	DNA topoisomerase III [Oceanobacter kriegii].	36.65	352	220	2	36	385	253	603	4e-69	244
rs:WP_033995596	DNA topoisomerase III [Pseudomonas aeruginosa].	33.63	446	268	7	31	459	236	670	4e-69	245
rs:WP_024589767	MULTISPECIES: DNA topoisomerase III [Pseudoalteromonas].	38.86	350	205	2	36	385	251	591	5e-69	243
rs:WP_016913643	DNA topoisomerase III [Halomonas stevensii].	35.84	385	230	4	35	414	241	613	5e-69	243
rs:WP_031383673	DNA topoisomerase III [Halomonas zincidurans].	37.46	355	207	2	35	385	242	585	5e-69	243
rs:WP_044342514	DNA topoisomerase III [Pseudomonas oryzihabitans].	39.37	348	209	1	61	408	267	612	5e-69	243
rs:WP_007587111	DNA topoisomerase III [Pseudoalteromonas sp. BSi20429].	38.57	350	206	2	36	385	251	591	6e-69	243
rs:WP_044628054	DNA topoisomerase III [Halomonas meridiana].	37.89	351	205	3	35	384	242	580	6e-69	243
rs:WP_045892466	DNA topoisomerase III [Clostridium botulinum].	37.16	366	214	5	37	391	231	591	7e-69	244
rs:WP_041158384	DNA topoisomerase III [Halomonas sp. KHS3].	38.19	343	199	3	35	376	242	572	7e-69	242
rs:WP_024651600	DNA topoisomerase III [Pseudomonas syringae].	35.21	443	256	8	33	459	240	667	7e-69	244
rs:WP_024690810	DNA topoisomerase III [Pseudomonas syringae].	34.76	443	258	8	33	459	240	667	7e-69	244
rs:WP_040262903	DNA topoisomerase III [Pseudomonas sp. CB1].	34.21	418	241	3	25	408	230	647	7e-69	243
rs:WP_022523733	DNA topoisomerase III [Halomonas sp. A3H3].	38.19	343	199	3	35	376	242	572	8e-69	242
rs:WP_026742443	DNA topoisomerase III [Lonsdalea quercina].	35.00	380	239	3	36	414	251	623	8e-69	242
rs:WP_015924446	DNA topoisomerase III [[Clostridium] cellulolyticum].	37.80	410	237	7	32	435	229	626	8e-69	244
rs:WP_039858283	DNA topoisomerase III [Halomonas titanicae].	37.82	357	205	4	21	376	232	572	8e-69	242
rs:WP_024668846	DNA topoisomerase III, partial [Pseudomonas syringae].	34.76	443	258	8	33	459	240	667	8e-69	243
rs:WP_023180744	topoisomerase [Salmonella enterica].	32.40	466	282	7	3	459	217	658	8e-69	244
rs:WP_042317047	DNA topoisomerase III, partial [Desulfotomaculum acetoxidans].	39.06	361	207	6	31	386	230	582	8e-69	243
rs:WP_009724609	DNA topoisomerase III [Halomonas sp. TD01].	38.19	343	199	3	35	376	242	572	9e-69	242
rs:WP_032679819	DNA topoisomerase III [Enterobacter sp. BIDMC 26].	32.83	466	280	7	3	459	217	658	9e-69	244
rs:WP_007253354	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	34.76	443	258	8	33	459	240	667	1e-68	243
rs:WP_006705692	DNA topoisomerase III [Candidatus Regiella insecticola].	34.20	386	240	5	22	404	240	614	1e-68	242
rs:WP_044384737	DNA topoisomerase III [Marinobacter excellens].	32.78	479	264	4	32	459	250	721	1e-68	244
rs:WP_007114003	DNA topoisomerase III [Halomonas boliviensis].	37.89	351	205	3	35	384	242	580	1e-68	242
rs:WP_033032254	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	38.29	350	207	1	36	385	251	591	1e-68	242
rs:WP_010554574	DNA topoisomerase III [Pseudoalteromonas arctica].	38.57	350	206	2	36	385	251	591	1e-68	242
rs:WP_024603831	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	38.57	350	206	2	36	385	251	591	1e-68	242
tr:L9UC23_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	37.82	357	205	4	21	376	260	600	1e-68	242
rs:WP_027639809	DNA topoisomerase III [Clostridium cadaveris].	36.29	394	237	6	37	425	233	617	1e-68	243
rs:WP_008984953	DNA topoisomerase III [Alishewanella agri].	37.10	345	213	1	36	376	251	595	1e-68	242
rs:WP_024603571	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	38.29	350	207	1	36	385	251	591	2e-68	241
rs:WP_007636905	DNA topoisomerase III [Paraglaciecola psychrophila].	37.30	370	224	4	35	399	250	616	2e-68	241
rs:WP_004666997	DNA topoisomerase III [Pseudomonas savastanoi].	35.66	415	246	5	33	432	240	648	2e-68	243
rs:WP_020304534	DNA topoisomerase III, partial [Pseudomonas syringae].	35.18	415	248	5	33	432	28	436	2e-68	238
rs:WP_005490789	DNA topoisomerase III [Pseudoalteromonas luteoviolacea].	35.31	405	234	3	35	439	250	626	2e-68	241
tr:C8VYF5_DESAS	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	39.06	361	207	6	31	386	229	581	2e-68	243
rs:WP_034582630	DNA topoisomerase III [Clostridium acetobutylicum].	36.00	400	242	5	40	435	236	625	2e-68	243
rs:WP_040193168	DNA topoisomerase III [Clostridium sp. CL-6].	37.78	352	216	3	36	385	232	582	2e-68	243
tr:S9RZV6_9RHOB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	39.22	357	207	7	102	449	3	358	2e-68	238
rs:WP_010073946	DNA topoisomerase III [Clostridium cellulovorans].	39.39	358	201	5	36	385	232	581	2e-68	243
rs:WP_024608331	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	38.57	350	206	2	36	385	251	591	2e-68	241
rs:WP_007377458	MULTISPECIES: DNA topoisomerase III [Pseudoalteromonas].	38.00	350	208	1	36	385	251	591	3e-68	241
rs:WP_047625923	DNA topoisomerase III [Enterobacter sp. ZOR0014].	32.40	466	282	7	3	459	217	658	3e-68	243
rs:WP_010966230	DNA topoisomerase III [Clostridium acetobutylicum].	36.00	400	242	5	40	435	236	625	3e-68	243
rs:WP_002961727	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	38.00	350	208	1	36	385	251	591	3e-68	241
rs:WP_033017260	DNA topoisomerase III [Pseudoalteromonas sp. BSi20652].	38.29	350	207	2	36	385	251	591	3e-68	241
rs:WP_043332461	DNA topoisomerase III [Cobetia marina].	35.32	402	238	4	35	414	254	655	4e-68	242
rs:WP_005214016	DNA topoisomerase III [Clostridium celatum].	35.73	403	233	6	36	428	232	618	4e-68	242
rs:WP_010454695	DNA topoisomerase III [Succinivibrionaceae bacterium WG-1].	36.19	373	227	5	35	397	244	615	4e-68	243
rs:WP_047000850	DNA topoisomerase III [Clostridium beijerinckii].	36.11	396	243	5	36	428	232	620	4e-68	242
tr:G7EED8_9GAMM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.29	350	207	2	36	385	258	598	4e-68	241
rs:WP_008137957	DNA topoisomerase III [Pseudoalteromonas sp. BSi20495].	38.00	350	208	1	36	385	251	591	4e-68	240
rs:WP_011877338	DNA topoisomerase III [Desulfotomaculum reducens].	34.93	438	266	7	22	450	215	642	4e-68	243
rs:WP_045394961	DNA topoisomerase III [Vibrio rotiferianus].	34.68	421	249	8	22	438	238	636	4e-68	241
rs:WP_035578786	DNA topoisomerase III [Halomonas sp. TG39a].	37.64	348	204	3	30	376	237	572	4e-68	240
tr:Q3II03_PSEHT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	38.00	350	208	2	36	385	103	443	5e-68	237
rs:WP_016206725	DNA topoisomerase III [Clostridium sartagoforme].	36.11	396	243	5	36	428	232	620	5e-68	242
rs:WP_037009569	DNA topoisomerase III, partial [Pseudomonas sp. RL].	36.29	350	222	1	58	406	264	613	5e-68	239
rs:WP_045886111	DNA topoisomerase III [Clostridium sporogenes].	38.00	350	213	3	46	391	242	591	6e-68	242
rs:WP_011507443	DNA topoisomerase III [Chromohalobacter salexigens].	33.10	423	253	3	35	438	242	653	6e-68	240
rs:WP_024597194	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	38.00	350	208	1	36	385	251	591	6e-68	240
rs:WP_003486940	DNA topoisomerase III [Clostridium sporogenes].	38.29	350	212	3	46	391	242	591	7e-68	241
rs:WP_043031774	DNA topoisomerase III [Clostridium botulinum].	38.29	350	212	3	46	391	242	591	7e-68	241
rs:WP_037587002	DNA topoisomerase III, partial [Stenoxybacter acetivorans].	36.34	388	237	4	23	404	198	581	7e-68	238
rs:WP_009170744	DNA topoisomerase III [Clostridium sp. DL-VIII].	34.75	400	241	5	36	428	232	618	7e-68	241
rs:WP_003490483	MULTISPECIES: DNA topoisomerase III [Clostridium].	37.71	350	214	3	46	391	242	591	8e-68	241
rs:WP_045519608	DNA topoisomerase III [Clostridium sporogenes].	37.71	350	214	3	46	391	242	591	9e-68	241
rs:WP_046870172	DNA topoisomerase III, partial [Clostridium sporogenes].	37.71	350	214	3	46	391	242	591	1e-67	241
rs:WP_016708066	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	37.32	351	211	2	36	386	251	592	1e-67	239
rs:WP_031599028	DNA topoisomerase III, partial [Pseudomonas savastanoi].	35.54	408	242	5	33	425	240	641	1e-67	239
rs:WP_018915941	DNA topoisomerase III [Halomonas zhanjiangensis].	37.04	351	208	3	35	384	242	580	1e-67	239
rs:WP_006122530	DNA topoisomerase III [Pantoea stewartii].	32.62	466	281	7	3	459	217	658	1e-67	241
rs:WP_031828430	DNA topoisomerase III [Vibrio parahaemolyticus].	35.48	403	235	6	22	421	238	618	1e-67	239
rs:WP_003407083	DNA topoisomerase III [Pseudomonas syringae].	34.23	444	260	8	33	459	240	668	2e-67	240
rs:WP_026881876	DNA topoisomerase III [Clostridium akagii].	35.90	390	227	6	47	425	243	620	2e-67	240
rs:WP_030034462	DNA topoisomerase III [Clostridium botulinum].	37.71	350	214	3	46	391	242	591	2e-67	240
rs:WP_005614699	DNA topoisomerase III [Pseudomonas avellanae].	34.39	442	261	7	33	459	240	667	2e-67	240
tr:A0A0D6EA40_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	37.64	348	204	3	30	376	237	572	2e-67	239
rs:WP_014314712	DNA topoisomerase III [Clostridium sp. BNL1100].	37.96	411	236	7	32	435	229	627	2e-67	240
rs:WP_025460229	DNA topoisomerase III [Neisseria meningitidis].	33.41	434	267	8	36	451	245	674	2e-67	239
rs:WP_038612558	DNA topoisomerase III [Pseudomonas alkylphenolia].	37.81	365	223	2	67	431	273	633	3e-67	238
rs:WP_043511603	DNA topoisomerase III, partial [Halomonas sp. BC04].	35.88	379	221	4	69	436	4	371	3e-67	231
rs:WP_022614817	DNA topoisomerase [Vibrio nigripulchritudo].	31.02	490	266	9	35	459	244	726	3e-67	240
rs:WP_003436835	MULTISPECIES: DNA topoisomerase III [Pseudomonas syringae group].	35.18	415	248	5	33	432	240	648	3e-67	239
rs:WP_022746718	DNA topoisomerase 3 [Clostridium saccharobutylicum].	34.76	397	242	5	36	425	232	618	3e-67	239
rs:WP_011590864	DNA topoisomerase III [Clostridium perfringens].	38.14	354	211	5	36	385	234	583	3e-67	239
rs:WP_037587648	DNA topoisomerase III, partial [Stenoxybacter acetivorans].	34.82	382	235	4	21	388	195	576	3e-67	237
tr:B1R566_CLOPF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.92	356	209	7	36	385	231	580	4e-67	239
rs:WP_040259218	DNA topoisomerase III [Pseudomonas sp. CB1].	34.31	443	262	6	33	459	240	669	4e-67	239
rs:WP_042265979	DNA topoisomerase III [Clostridium perfringens].	37.92	356	209	7	36	385	234	583	4e-67	239
rs:WP_034833148	DNA topoisomerase III [Clostridium perfringens].	37.92	356	209	7	36	385	234	583	4e-67	239
tr:B1BWJ0_CLOPF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.88	359	205	7	36	385	231	580	4e-67	239
rs:WP_044325068	DNA topoisomerase III, partial [Pseudomonas amygdali].	37.97	345	197	5	74	404	30	371	4e-67	233
rs:WP_019951680	DNA topoisomerase III [Kushneria aurantia].	32.92	407	255	3	31	433	238	630	5e-67	238
rs:WP_010217635	DNA topoisomerase III [Pseudomonas amygdali].	35.18	415	248	5	33	432	240	648	5e-67	239
rs:WP_035565951	DNA topoisomerase III [Halomonas sp. KO116].	37.61	343	201	3	35	376	242	572	5e-67	237
rs:WP_044705422	DNA topoisomerase III [Escherichia coli].	31.19	436	276	5	31	458	237	656	5e-67	239
tr:B1V109_CLOPF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.92	356	209	7	36	385	231	580	6e-67	239
rs:WP_043013202	DNA topoisomerase III [Clostridium perfringens].	37.88	359	205	7	36	385	234	583	6e-67	239
rs:WP_043014029	DNA topoisomerase III [Clostridium perfringens].	37.92	356	209	7	36	385	234	583	6e-67	239
rs:WP_044322475	DNA topoisomerase III, partial [Pseudomonas amygdali].	36.77	378	222	3	33	396	240	614	6e-67	237
rs:WP_042562302	hypothetical protein [Yersinia frederiksenii].	31.78	450	269	9	28	458	243	673	9e-67	239
gpu:CP011230_804	DNA topoisomerase III [[Haemophilus] ducreyi]	35.54	377	224	3	20	385	225	593	9e-67	237
rs:WP_027631371	DNA topoisomerase III [Clostridium hydrogeniformans].	37.96	353	189	5	47	384	243	580	9e-67	238
tr:F3FGU8_PSESX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	39.55	311	186	1	61	371	267	575	9e-67	235
rs:WP_034612451	DNA topoisomerase III [Desulfosporosinus sp. Tol-M].	37.56	410	240	7	30	435	229	626	9e-67	238
rs:WP_047919008	DNA topoisomerase III [Neisseria gonorrhoeae].	33.72	436	263	9	36	451	245	674	1e-66	238
rs:WP_002556105	DNA topoisomerase III [Pseudomonas savastanoi].	35.18	415	248	5	33	432	240	648	1e-66	238
tr:B1BJK1_CLOPF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.92	356	209	7	36	385	231	580	1e-66	238
rs:WP_008679336	DNA topoisomerase III [Clostridium sp. 7_2_43FAA].	37.12	361	218	5	36	391	232	588	1e-66	238
tr:Q0SSU9_CLOPS	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.92	356	209	7	36	385	234	583	1e-66	238
rs:WP_042259147	DNA topoisomerase III [Clostridium perfringens].	37.92	356	209	7	36	385	234	583	1e-66	238
rs:WP_023004588	DNA topoisomerase III [Halomonas sp. PBN3].	35.69	367	225	1	35	401	242	597	1e-66	236
rs:WP_044320067	DNA topoisomerase III [Pseudomonas amygdali].	34.17	439	260	7	36	459	243	667	1e-66	238
rs:WP_001562921	DNA topoisomerase III [Escherichia coli].	31.19	436	276	5	31	458	237	656	1e-66	238
tr:Q8XK95_CLOPE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.92	356	209	7	36	385	231	580	1e-66	238
rs:WP_034834689	DNA topoisomerase III [Clostridium perfringens].	37.92	356	209	7	36	385	234	583	1e-66	238
rs:WP_017548815	DNA topoisomerase III [Salinicoccus carnicancri].	36.10	374	220	5	28	393	227	589	1e-66	238
rs:WP_044422738	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	34.54	443	259	8	33	459	240	667	1e-66	238
rs:WP_011411189	DNA topoisomerase III [Sodalis glossinidius].	37.61	351	209	4	36	385	251	592	1e-66	236
rs:WP_014967282	DNA topoisomerase III [Gottschalkia acidurici].	36.49	359	211	6	48	397	245	595	1e-66	238
rs:WP_032121230	DNA topoisomerase III [Clostridium sp. LF2].	37.78	352	205	4	47	391	243	587	1e-66	238
rs:WP_042968702	DNA topoisomerase III [Escherichia coli].	30.96	436	277	5	31	458	237	656	2e-66	238
gp:CP003909_766	DNA topoisomerase III [Neisseria gonorrhoeae MS11]	33.72	436	263	9	36	451	228	657	2e-66	236
rs:WP_007785444	DNA topoisomerase III [Desulfosporosinus youngiae].	35.77	411	248	6	30	435	229	628	2e-66	238
rs:WP_042773587	hypothetical protein, partial [Salmonella enterica].	32.71	428	271	4	23	449	236	647	2e-66	236
rs:WP_035131896	DNA topoisomerase III [Clostridium sulfidigenes].	36.29	383	234	6	46	425	242	617	2e-66	237
tr:H7CWN7_CLOPF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	38.20	356	208	7	36	385	231	580	2e-66	237
gpu:CP012026_571	236	33.72	436	263	9	36	451	228	657	2e-66
rs:WP_034824013	DNA topoisomerase III [Clostridium perfringens].	38.20	356	208	7	36	385	234	583	2e-66	237
rs:WP_003695219	DNA topoisomerase III [Neisseria gonorrhoeae].	33.72	436	263	9	36	451	245	674	2e-66	236
rs:WP_004620647	DNA topoisomerase III [[Clostridium] papyrosolvens].	37.93	406	233	7	37	435	234	627	3e-66	237
rs:WP_005746149	DNA topoisomerase III [Pseudomonas amygdali].	34.94	415	249	5	33	432	240	648	3e-66	237
rs:WP_023195012	DNA topoisomerase III, partial [Salmonella enterica].	39.67	300	173	3	86	385	5	296	3e-66	228
rs:WP_023975063	DNA topoisomerase III [Clostridium pasteurianum].	36.64	363	215	5	36	391	232	586	3e-66	237
rs:WP_006714537	DNA topoisomerase III [Vibrio ichthyoenteri].	33.86	443	263	10	22	459	238	655	3e-66	236
rs:WP_044423982	DNA topoisomerase III [Pseudomonas savastanoi].	35.18	415	248	5	33	432	240	648	3e-66	237
rs:WP_003699926	DNA topoisomerase III [Neisseria gonorrhoeae].	33.72	436	263	9	36	451	245	674	3e-66	236
rs:WP_003693191	DNA topoisomerase 3 [Neisseria gonorrhoeae].	33.72	436	263	9	36	451	245	674	3e-66	236
rs:WP_033910510	DNA topoisomerase III [Neisseria gonorrhoeae].	33.72	436	263	9	36	451	245	674	3e-66	236
rs:WP_011282541	DNA topoisomerase III [Pseudomonas savastanoi].	35.18	415	248	5	33	432	240	648	3e-66	237
rs:WP_041895902	DNA topoisomerase III [Clostridium beijerinckii].	36.64	363	215	5	36	391	232	586	3e-66	237
rs:WP_024833195	DNA topoisomerase III [[Clostridium] josui].	37.93	406	233	7	37	435	234	627	4e-66	236
rs:WP_008422242	DNA topoisomerase III [Clostridium sp. Maddingley MBC34-26].	34.25	400	243	6	36	428	232	618	4e-66	237
rs:WP_042677102	DNA topoisomerase III, partial [Pantoea sp. B40].	41.22	296	166	3	36	331	116	403	4e-66	229
rs:WP_007062346	DNA topoisomerase III [Clostridium carboxidivorans].	37.22	352	218	3	43	391	239	590	4e-66	237
rs:WP_047707015	DNA topoisomerase III [Plesiomonas sp. ZOR0011].	35.14	387	241	3	38	421	247	626	4e-66	236
rs:WP_019716635	DNA topoisomerase III, partial [Pseudomonas syringae].	35.49	386	232	3	33	404	240	622	4e-66	235
rs:WP_017684961	DNA topoisomerase III [Pseudomonas syringae].	35.49	386	232	3	33	404	240	622	5e-66	234
tr:C9LWM4_SELS3	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.89	475	275	11	1	458	213	665	5e-66	236
tr:B1RGM1_CLOPF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	37.64	356	210	7	36	385	231	580	5e-66	236
rs:WP_013740648	DNA topoisomerase III [Selenomonas sputigena].	33.89	475	275	11	1	458	212	664	5e-66	236
rs:WP_020816211	DNA topoisomerase III [[Clostridium] papyrosolvens].	37.68	406	234	7	37	435	234	627	5e-66	236
rs:WP_042262170	DNA topoisomerase III [Clostridium perfringens].	37.64	356	210	7	36	385	234	583	6e-66	236
rs:WP_039771836	DNA topoisomerase III [Clostridium diolis].	36.64	363	215	5	36	391	232	586	6e-66	236
tr:V2C251_SALET	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	39.74	302	174	3	36	337	251	544	6e-66	234
rs:WP_042267858	DNA topoisomerase III [Clostridium perfringens].	37.64	356	210	7	36	385	234	583	6e-66	236
rs:WP_024962447	DNA topoisomerase III [Campylobacter ureolyticus].	31.96	438	280	9	33	459	234	664	7e-66	236
rs:WP_025370412	hypothetical protein [Campylobacter fetus].	33.02	424	262	6	35	449	240	650	7e-66	235
gpu:KP795518_1	DNA topoisomerase III [Aliivibrio fischeri]	35.37	393	243	3	32	421	235	619	8e-66	234
rs:WP_014795822	DNA topoisomerase III [Desulfitobacterium dehalogenans].	38.50	400	227	8	36	428	233	620	8e-66	236
rs:WP_017209631	DNA topoisomerase III [Clostridium beijerinckii].	36.36	363	216	5	36	391	232	586	9e-66	236
tr:W4V5H9_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	36.06	391	240	5	40	428	69	451	9e-66	232
rs:WP_029163365	DNA topoisomerase III [Clostridium scatologenes].	36.93	352	219	3	43	391	239	590	1e-65	236
rs:WP_013123595	DNA topoisomerase III [Thiomonas intermedia].	34.68	444	257	12	22	459	232	648	1e-65	235
rs:WP_010243805	DNA topoisomerase III [Acetivibrio cellulolyticus].	39.61	356	207	4	40	391	237	588	1e-65	235
rs:WP_011969196	DNA topoisomerase III [Clostridium beijerinckii].	36.36	363	216	5	36	391	232	586	1e-65	235
rs:WP_005815481	DNA topoisomerase III [Desulfitobacterium hafniense].	36.93	398	236	5	36	428	233	620	1e-65	235
rs:WP_015945463	DNA topoisomerase III [Desulfitobacterium hafniense].	36.93	398	236	5	36	428	233	620	2e-65	235
rs:WP_015061875	DNA topoisomerase III [Pseudomonas syringae].	34.70	415	250	5	33	432	240	648	2e-65	235
rs:WP_045576535	DNA topoisomerase III, partial [Desulfosporosinus sp. I2].	36.41	423	241	7	30	439	229	636	2e-65	235
rs:WP_020207144	DNA topoisomerase III, partial [Cupriavidus sp. WS].	36.91	317	194	2	61	375	267	579	2e-65	232
rs:WP_035294111	DNA topoisomerase III [Clostridium sp. KNHs214].	34.29	420	248	7	29	435	229	633	2e-65	235
rs:WP_026771933	DNA topoisomerase III [Sediminibacillus halophilus].	34.55	385	234	6	47	425	244	616	2e-65	234
rs:WP_035412123	DNA topoisomerase III [Chromohalobacter israelensis].	32.62	423	255	3	35	438	242	653	2e-65	233
rs:WP_003366695	DNA topoisomerase III [Clostridium botulinum].	35.59	399	232	6	47	435	244	627	2e-65	234
rs:WP_032076274	DNA topoisomerase III [Clostridium drakei].	36.93	352	219	3	43	391	239	590	2e-65	234
rs:WP_015392895	DNA topoisomerase 3 [Clostridium saccharoperbutylacetonicum].	35.26	363	220	5	36	391	232	586	3e-65	234
rs:WP_023043465	hypothetical protein [Photorhabdus temperata].	32.21	447	277	8	23	459	230	660	3e-65	235
rs:WP_039022797	DNA topoisomerase III, partial [Escherichia coli].	32.53	415	263	5	39	443	2	409	3e-65	228
rs:WP_026570896	DNA topoisomerase III [Bacillus sp. NSP22.2].	34.55	385	234	6	47	425	244	616	4e-65	234
rs:WP_027313023	DNA topoisomerase III [Balneatrix alpica].	37.13	369	222	3	24	392	229	587	4e-65	232
rs:WP_032707380	DNA topoisomerase III, partial [Pseudomonas savastanoi].	34.46	415	251	5	33	432	151	559	4e-65	232
rs:WP_041603685	DNA topoisomerase III [[Haemophilus] ducreyi].	35.49	355	221	2	36	390	252	598	4e-65	232
gpu:CP011222_916	DNA topoisomerase III [[Haemophilus] ducreyi]	35.49	355	221	2	36	390	252	598	4e-65	232
tr:Q7VLX0_HAEDU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	35.49	355	221	2	36	390	253	599	5e-65	232
rs:WP_022211736	DNA topoisomerase III [Clostridium sp. CAG:265].	36.91	363	214	4	36	391	232	586	5e-65	233
tr:E2XSJ8_PSEFL	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFQ63312.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFQ63312.1};	39.87	301	168	5	154	454	1	288	7e-65	223
rs:WP_021562493	hypothetical protein [Escherichia coli].	32.29	449	274	8	27	459	239	673	7e-65	234
rs:WP_033798032	DNA topoisomerase III, partial [Bacillus mycoides].	35.50	369	227	6	39	401	55	418	7e-65	229
tr:I2X3M9_ECOLX	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EII43599.1};	32.53	415	263	5	39	443	20	427	8e-65	228
rs:WP_040241684	DNA topoisomerase III [Chromohalobacter japonicus].	33.50	406	249	3	35	436	242	630	8e-65	231
rs:WP_019851501	DNA topoisomerase III [Desulfitobacterium sp. PCE1].	38.25	400	228	8	36	428	233	620	8e-65	233
rs:WP_021325878	DNA topoisomerase III [Photorhabdus temperata].	31.99	447	278	8	23	459	230	660	9e-65	233
rs:WP_010296837	DNA topoisomerase III [Clostridium senegalense].	37.76	392	234	7	37	425	233	617	9e-65	233
rs:WP_040187403	DNA topoisomerase III [Halomonas salina].	33.58	402	246	3	35	436	242	622	9e-65	231
rs:WP_018212069	DNA topoisomerase III [Desulfitobacterium hafniense].	36.93	398	236	5	36	428	233	620	9e-65	233
rs:WP_006803319	DNA topoisomerase III [Helicobacter winghamensis].	33.18	443	274	10	32	459	233	668	1e-64	233
rs:WP_042101431	DNA topoisomerase III, partial [Escherichia coli].	36.13	346	202	4	91	436	1	327	1e-64	223
tr:A0A098B862_DESHA	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	36.68	398	237	5	36	428	233	620	1e-64	233
rs:WP_011462224	DNA topoisomerase III [Desulfitobacterium hafniense].	36.68	398	237	5	36	428	233	620	1e-64	233
rs:WP_035437661	DNA topoisomerase III [Bacillus sp. UNC322MFChir4.1].	36.63	374	224	7	36	401	231	599	1e-64	233
rs:WP_033873156	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	40.07	282	168	1	61	341	267	548	1e-64	229
rs:WP_039238656	MULTISPECIES: DNA topoisomerase III [Clostridium].	36.83	372	210	6	74	435	271	627	1e-64	232
rs:WP_011722818	DNA topoisomerase III [Clostridium novyi].	36.83	372	210	6	74	435	271	627	1e-64	232
rs:WP_039245269	DNA topoisomerase III [Clostridium novyi].	36.83	372	210	6	74	435	271	627	2e-64	232
rs:WP_009353583	DNA topoisomerase, partial [Veillonella sp. oral taxon 780].	33.73	424	263	8	36	449	214	629	2e-64	231
rs:WP_019331405	DNA topoisomerase III [Pseudomonas syringae].	34.22	415	252	5	33	432	240	648	2e-64	232
rs:WP_032340913	DNA topoisomerase III, partial [Escherichia coli].	32.45	413	262	5	41	443	1	406	2e-64	226
rs:WP_039250550	DNA topoisomerase III [Clostridium novyi].	36.83	372	210	6	74	435	271	627	2e-64	232
rs:WP_042882881	hypothetical protein [Cupriavidus necator].	36.53	375	222	7	33	399	265	631	2e-64	230
rs:WP_039226428	DNA topoisomerase III [Clostridium novyi].	36.83	372	210	6	74	435	271	627	2e-64	232
rs:WP_032904947	DNA topoisomerase III [Yersinia enterocolitica].	32.62	420	260	6	37	443	245	654	3e-64	231
rs:WP_044858971	DNA topoisomerase III, partial [Enterobacter cloacae].	39.33	300	174	3	86	385	7	298	3e-64	222
tr:R7TCT6_CAPTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	38.93	298	180	2	32	328	143	439	5e-64	224
rs:WP_033716935	DNA topoisomerase III, partial [Bacillus cereus].	36.21	359	220	5	48	401	64	418	5e-64	227
rs:WP_039256074	DNA topoisomerase III [Clostridium novyi].	35.09	399	234	6	47	435	244	627	5e-64	231
rs:WP_013823470	DNA topoisomerase III [Desulfotomaculum kuznetsovii].	34.20	424	260	5	38	452	237	650	6e-64	232
rs:WP_013106257	DNA topoisomerase III [Thiomonas arsenitoxydans].	33.64	428	261	6	35	459	239	646	6e-64	231
tr:J8ACM7_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	36.21	359	220	5	48	401	78	432	6e-64	228
tr:W1F122_ECOLX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CDL27510.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDL27510.1};	56.59	182	75	2	277	458	3	180	6e-64	216
rs:WP_034143173	DNA topoisomerase III [Desulfosporosinus sp. BICA1-9].	36.12	418	239	7	30	435	229	630	6e-64	231
rs:WP_026887816	DNA topoisomerase III [Clostridium beijerinckii].	34.99	363	220	4	36	391	232	585	8e-64	230
rs:WP_022168149	DNA topoisomerase III [Clostridium sp. CAG:221].	36.41	379	223	5	36	404	232	602	8e-64	230
rs:WP_027349624	DNA topoisomerase III [Halotalea alkalilenta].	34.02	388	237	3	21	400	233	609	9e-64	229
rs:WP_038167017	DNA topoisomerase III, partial [Vibrio shilonii].	30.72	446	277	6	31	459	92	522	9e-64	228
rs:WP_044310701	DNA topoisomerase III [Pseudomonas syringae].	33.64	440	261	8	36	459	243	667	1e-63	230
rs:WP_035196071	DNA topoisomerase III [Bacillus azotoformans].	36.25	400	237	8	47	439	245	633	1e-63	230
rs:WP_016132338	DNA topoisomerase 3 [Bacillus cereus].	35.41	370	228	6	39	402	236	600	1e-63	230
rs:WP_018766530	DNA topoisomerase III [Bacillus sp. 105MF].	35.50	369	227	6	39	401	236	599	1e-63	230
rs:WP_011998820	DNA topoisomerase III [Vibrio campbellii].	30.89	450	278	8	26	459	238	670	1e-63	230
rs:WP_003205730	MULTISPECIES: DNA topoisomerase III [Bacillus].	35.50	369	227	6	39	401	236	599	1e-63	230
tr:A0A0F4WVS4_9CLOT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KJZ97844.1};	35.63	348	214	3	46	391	18	357	1e-63	225
rs:WP_031611768	DNA topoisomerase III, partial [Salmonella enterica].	32.13	417	266	5	37	443	86	495	1e-63	226
rs:WP_041668451	DNA topoisomerase III, partial [Ralstonia pickettii].	39.23	311	187	2	32	341	237	546	1e-63	226
rs:WP_032177407	DNA topoisomerase III, partial [Escherichia coli].	32.27	409	260	5	45	443	1	402	1e-63	223
rs:WP_012101445	DNA topoisomerase III [Clostridium kluyveri].	36.53	386	225	6	47	425	243	615	1e-63	229
rs:WP_046427909	hypothetical protein [Burkholderia vietnamiensis].	36.32	424	246	10	35	452	254	659	1e-63	228
rs:WP_044322592	DNA topoisomerase III, partial [Pseudomonas amygdali].	37.25	357	207	5	36	378	244	597	1e-63	227
tr:B9E0J7_CLOK1	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	36.53	386	225	6	47	425	245	617	2e-63	229
rs:WP_009766587	DNA topoisomerase III [Sporosarcina newyorkensis].	35.69	367	226	5	37	397	235	597	2e-63	229
rs:WP_031545111	DNA topoisomerase III [Salinicoccus luteus].	36.65	382	222	7	28	405	227	592	2e-63	229
rs:WP_040757782	DNA topoisomerase III, partial [Vibrio scophthalmi].	31.54	447	271	6	31	459	241	670	2e-63	229
rs:WP_044322571	DNA topoisomerase III, partial [Pseudomonas amygdali].	35.73	375	224	3	36	396	243	614	2e-63	228
rs:WP_029573705	DNA topoisomerase III, partial [Pseudomonas syringae].	39.60	298	178	1	61	358	267	562	2e-63	226
rs:WP_039075817	DNA topoisomerase III [Bacillus sp. MSP13].	35.52	442	265	9	1	435	199	627	2e-63	229
rs:WP_013779520	DNA topoisomerase III [Tepidanaerobacter acetatoxydans].	35.24	403	246	6	40	435	237	631	2e-63	229
rs:WP_046058708	DNA topoisomerase III, partial [Clostridium sp. IBUN13A].	35.63	348	214	3	46	391	29	368	2e-63	225
rs:WP_008521801	DNA topoisomerase III [Jonquetella anthropi].	39.44	360	211	4	30	385	239	595	2e-63	228
rs:WP_044295331	DNA topoisomerase III [Pseudomonas amygdali].	38.99	336	193	4	120	452	183	509	2e-63	225
rs:WP_040435932	DNA topoisomerase III [[Clostridium] hylemonae].	34.47	412	249	7	27	428	226	626	2e-63	229
rs:WP_038354068	DNA topoisomerase III [Eubacterium limosum].	37.63	388	224	8	47	428	244	619	2e-63	229
rs:WP_013842511	DNA topoisomerase III [Desulfotomaculum ruminis].	32.89	447	265	8	18	446	210	639	2e-63	230
tr:C0C5H6_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	34.47	412	249	7	27	428	238	638	2e-63	229
rs:WP_014029288	DNA topoisomerase III [Acidithiobacillus ferrivorans].	44.48	299	155	6	31	328	232	520	2e-63	227
rs:WP_001140204	DNA topoisomerase III [Bacillus cereus].	35.95	370	224	5	39	401	236	599	2e-63	229
rs:WP_038228795	DNA topoisomerase III [Vibrio sp. ER1A].	31.39	446	274	7	31	459	241	671	2e-63	229
rs:WP_048406151	DNA topoisomerase III, partial [Bacillus sp. KJ-17].	35.84	413	247	8	19	425	163	563	3e-63	228
rs:WP_001235761	DNA topoisomerase III [Escherichia coli].	32.37	417	265	5	37	443	245	654	3e-63	229
rs:WP_028395884	DNA topoisomerase III [Bacillus sp. FJAT-14578].	35.25	400	240	8	47	439	244	631	3e-63	229
tr:F9RIF7_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.54	447	271	6	31	459	242	671	3e-63	229
sp:TOP3_BACLD	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	37.21	387	234	5	19	401	216	597	3e-63	229
gp:CP000002_471	DNA topoisomerase III [Bacillus licheniformis DSM 13 = ATCC 14580]	37.21	387	234	5	19	401	218	599	3e-63	229
rs:WP_045644923	DNA topoisomerase III [Peptococcaceae bacterium BRH_c4b].	35.82	402	236	6	39	425	233	627	3e-63	228
rs:WP_045368045	DNA topoisomerase III [Vibrio campbellii].	31.19	452	274	9	26	459	238	670	3e-63	229
rs:WP_033426626	DNA topoisomerase III, partial [Salinicoccus albus].	36.49	370	213	6	35	394	124	481	3e-63	227
rs:WP_045144547	DNA topoisomerase III [Clostridium butyricum].	35.92	348	213	3	46	391	242	581	3e-63	229
rs:WP_002580164	DNA topoisomerase III [Clostridium butyricum].	35.92	348	213	3	46	391	242	581	3e-63	228
gp:AE017333_478	DNA topoisomerase III [Bacillus licheniformis DSM 13 = ATCC 14580]	37.21	387	234	5	19	401	219	600	3e-63	229
rs:WP_012908954	DNA topoisomerase III [Citrobacter rodentium].	32.38	420	261	6	37	443	245	654	3e-63	228
rs:WP_003427476	DNA topoisomerase III [Clostridium butyricum].	35.92	348	213	3	46	391	242	581	4e-63	228
rs:WP_027635678	DNA topoisomerase III [Clostridium butyricum].	35.92	348	213	3	46	391	242	581	4e-63	228
rs:WP_039285186	DNA topoisomerase III [Clostridium botulinum].	34.84	399	235	6	47	435	244	627	4e-63	228
rs:WP_046130259	DNA topoisomerase III [Bacillus sp. TH008].	36.01	411	249	7	19	425	216	616	4e-63	228
rs:WP_001235758	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	32.38	420	261	6	37	443	245	654	4e-63	228
rs:WP_014611673	DNA topoisomerase [Shewanella putrefaciens].	32.68	459	273	7	35	459	250	706	4e-63	228
tr:R9TS34_BACLI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	36.01	411	249	7	19	425	218	618	4e-63	228
rs:WP_022954113	conjugal transfer protein TraE [Leucothrix mucor].	31.49	489	256	8	25	449	229	702	4e-63	228
rs:WP_003414618	DNA topoisomerase III [Clostridium butyricum].	35.92	348	213	3	46	391	242	581	4e-63	228
rs:WP_006073986	DNA topoisomerase III [Vibrio shilonii].	31.39	446	274	7	31	459	241	671	5e-63	228
rs:WP_016885166	DNA topoisomerase III [Bacillus licheniformis].	37.21	387	234	5	19	401	227	608	5e-63	228
rs:WP_026585960	DNA topoisomerase III [Bacillus sp. NSP9.1].	36.04	394	230	6	40	425	237	616	5e-63	228
rs:WP_041817152	DNA topoisomerase III [Bacillus licheniformis].	36.01	411	249	7	19	425	226	626	5e-63	228
rs:WP_039170259	conjugal transfer protein TraE [Gallibacterium anatis].	32.48	431	263	8	38	458	251	663	5e-63	228
rs:WP_028393890	DNA topoisomerase III [Bacillus sp. FJAT-14515].	37.23	368	220	6	40	401	238	600	5e-63	228
rs:WP_032242288	DNA topoisomerase III, partial [Escherichia coli].	32.13	417	266	5	37	443	221	630	5e-63	228
rs:WP_003179052	DNA topoisomerase III [Bacillus licheniformis].	37.21	387	234	5	19	401	227	608	6e-63	228
rs:WP_033713469	DNA topoisomerase III, partial [Bacillus cereus].	35.39	373	230	6	36	401	41	409	6e-63	224
tr:W1U302_CLOBU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	35.92	348	213	3	46	391	269	608	6e-63	228
rs:WP_047952027	DNA topoisomerase III, partial [Neisseria gonorrhoeae].	35.23	386	224	9	86	451	30	409	6e-63	221
rs:WP_027631203	DNA topoisomerase III [[Clostridium] cellobioparum].	36.48	392	238	5	47	435	244	627	7e-63	228
rs:WP_032242577	DNA topoisomerase III [Escherichia coli].	32.13	417	266	5	37	443	245	654	7e-63	228
rs:WP_032201902	DNA topoisomerase III [Escherichia coli].	32.13	417	266	5	37	443	245	654	7e-63	228
rs:WP_001235740	DNA topoisomerase III [Escherichia coli].	32.13	417	266	5	37	443	245	654	7e-63	228
tr:A0A061Q3G6_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.67	450	279	8	26	459	237	669	8e-63	228
rs:WP_036833466	DNA topoisomerase III [Pontibacillus litoralis].	36.90	374	221	7	36	401	232	598	8e-63	228
rs:WP_033715361	DNA topoisomerase III, partial [Bacillus cereus].	35.39	373	230	6	36	401	50	418	9e-63	224
rs:WP_029053986	DNA topoisomerase III [Sporosarcina ureae].	37.36	364	217	6	40	397	238	596	9e-63	228
rs:WP_024256650	DNA topoisomerase III [Escherichia coli].	32.13	417	266	5	37	443	245	654	9e-63	227
tr:A0A0C8ZUT9_SALTI	SubName: Full=TopB_3 protein {ECO:0000313|EMBL:CEU15733.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEU15733.1};	32.38	420	261	6	37	443	209	618	9e-63	226
rs:WP_001235741	DNA topoisomerase III [Escherichia coli].	32.13	417	266	5	37	443	245	654	9e-63	227
rs:WP_032349584	DNA topoisomerase III [Escherichia coli].	32.38	420	261	6	37	443	245	654	9e-63	227
rs:WP_001235742	DNA topoisomerase III [Escherichia coli].	32.13	417	266	5	37	443	245	654	1e-62	227
rs:WP_024167399	DNA topoisomerase III, partial [Escherichia coli].	32.38	420	261	6	37	443	214	623	1e-62	226
rs:WP_033559033	DNA topoisomerase III [Escherichia coli].	32.37	448	271	9	28	459	240	671	1e-62	228
rs:WP_034639106	DNA topoisomerase III [Bacillus manliponensis].	34.96	389	242	6	19	401	216	599	1e-62	227
tr:J8I0M2_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	35.39	373	230	6	36	401	60	428	1e-62	224
gpu:KP795704_37	DNA topoisomerase III [Vibrio tasmaniensis]	29.58	497	275	7	31	459	241	730	1e-62	227
rs:WP_012108053	DNA topoisomerase III [Campylobacter hominis].	31.51	438	282	9	33	459	234	664	1e-62	227
rs:WP_007084499	DNA topoisomerase III [Bacillus bataviensis].	34.41	401	251	5	39	435	236	628	1e-62	227
rs:WP_001235763	DNA topoisomerase III [Escherichia coli].	32.38	420	261	6	37	443	245	654	1e-62	227
tr:C3HV26_BACTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	35.38	359	223	5	48	401	48	402	1e-62	223
rs:WP_048231793	DNA topoisomerase III, partial [Escherichia coli].	31.90	420	263	6	37	443	65	474	1e-62	223
tr:R8H0D5_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	35.39	373	230	6	36	401	64	432	1e-62	224
rs:WP_031420250	DNA topoisomerase III [Vibrio parahaemolyticus].	28.83	489	279	4	35	459	245	728	1e-62	227
rs:WP_016731587	MULTISPECIES: DNA topoisomerase [Enterobacteriaceae].	32.38	420	261	6	37	443	245	654	1e-62	227
rs:WP_017154075	DNA topoisomerase III [Bacillus sp. FJAT-13831].	35.05	368	230	5	39	401	236	599	2e-62	227
rs:WP_001722392	DNA topoisomerase III family protein [Escherichia coli].	32.38	420	261	6	37	443	245	654	2e-62	226
rs:WP_045715631	DNA topoisomerase III, partial [Salmonella enterica].	31.90	420	263	6	37	443	83	492	2e-62	223
rs:WP_048231497	DNA topoisomerase III, partial [Escherichia coli].	32.14	420	262	6	37	443	156	565	2e-62	225
rs:WP_001235744	DNA topoisomerase III [Salmonella enterica].	32.38	420	261	6	37	443	245	654	2e-62	226
rs:WP_016112910	DNA topoisomerase 3 [Bacillus cereus].	35.23	369	228	6	39	401	236	599	2e-62	227
rs:WP_018305366	DNA topoisomerase III [Desulfitobacterium hafniense].	36.43	398	238	5	36	428	233	620	2e-62	227
rs:WP_001694638	DNA topoisomerase III family protein [Escherichia coli].	32.38	420	261	6	37	443	245	654	2e-62	226
rs:WP_021548626	hypothetical protein [Escherichia coli].	32.37	417	265	5	37	443	245	654	2e-62	226
rs:WP_001235739	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	32.13	417	266	5	37	443	245	654	2e-62	226
rs:WP_003329635	DNA topoisomerase III [Bacillus azotoformans].	35.75	400	239	8	47	439	245	633	2e-62	226
tr:A0A0B4ISV6_VIBHA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.11	450	277	9	26	459	238	670	2e-62	227
rs:WP_021533550	hypothetical protein [Escherichia coli].	32.14	420	262	6	37	443	245	654	2e-62	226
rs:WP_009330155	MULTISPECIES: DNA topoisomerase III [Bacillus].	36.95	387	235	5	19	401	227	608	2e-62	227
rs:WP_032302216	DNA topoisomerase III [Escherichia coli].	31.73	416	268	4	37	443	245	653	2e-62	226
rs:WP_038438416	DNA topoisomerase III [Salmonella enterica].	32.14	420	263	6	37	443	245	655	2e-62	226
rs:WP_034174036	DNA topoisomerase III [Escherichia coli].	32.38	420	261	6	37	443	245	654	2e-62	226
rs:WP_011983474	DNA topoisomerase III [Bacillus cytotoxicus].	34.18	392	246	5	48	435	245	628	2e-62	226
rs:WP_016241259	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	120	529	2e-62	224
rs:WP_040180632	DNA topoisomerase III, partial [Klebsiella pneumoniae].	33.04	451	268	10	27	459	27	461	2e-62	223
rs:WP_021558908	hypothetical protein [Escherichia coli].	31.89	417	267	5	37	443	245	654	2e-62	226
rs:WP_046511331	DNA topoisomerase III [Salinicoccus sp. SV-16].	35.00	380	206	6	24	385	224	580	2e-62	226
rs:WP_033155036	MULTISPECIES: DNA topoisomerase III [Bacillus].	35.77	411	250	7	19	425	226	626	2e-62	226
rs:WP_032285169	DNA topoisomerase III [Escherichia coli].	33.41	419	259	6	37	443	245	655	2e-62	226
rs:WP_021523567	hypothetical protein [Escherichia coli].	32.38	420	261	6	37	443	245	654	2e-62	226
rs:WP_004010072	DNA topoisomerase, partial [Escherichia coli].	32.14	420	262	6	37	443	229	638	2e-62	226
rs:WP_001505316	DNA topoisomerase III family protein [Escherichia coli].	31.90	420	263	6	37	443	245	654	2e-62	226
rs:WP_031613730	DNA topoisomerase III, partial [Salmonella enterica].	39.18	291	169	3	95	385	1	283	2e-62	217
rs:WP_001235765	DNA topoisomerase III [Escherichia coli].	31.89	417	267	5	37	443	245	654	3e-62	226
tr:W7RM55_BACLI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	35.77	411	250	7	19	425	216	616	3e-62	226
tr:C2Z2K2_BACCE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	36.49	359	219	5	48	401	249	603	3e-62	226
rs:WP_001129909	DNA topoisomerase III [Bacillus cereus].	36.49	359	219	5	48	401	245	599	3e-62	226
rs:WP_040376372	DNA topoisomerase III [Bacillus psychrosaccharolyticus].	34.67	424	256	8	17	435	221	628	3e-62	226
rs:WP_044722401	DNA topoisomerase III [Escherichia coli].	33.41	419	259	6	37	443	245	655	3e-62	226
rs:WP_042068605	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	245	654	3e-62	226
rs:WP_031604130	DNA topoisomerase III, partial [Salmonella enterica].	39.45	289	167	3	97	385	1	281	3e-62	216
rs:WP_040126097	DNA topoisomerase III [Escherichia coli].	31.89	417	267	5	37	443	245	654	3e-62	226
rs:WP_023934205	DNA topoisomerase [Photobacterium leiognathi].	30.12	498	273	9	30	459	239	729	3e-62	226
rs:WP_001503703	DNA topoisomerase III family protein, partial [Escherichia coli].	32.14	420	262	6	37	443	245	654	3e-62	225
rs:WP_033552208	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	245	654	3e-62	226
rs:WP_025755768	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	31.74	438	275	5	36	459	246	673	3e-62	226
rs:WP_041114359	DNA topoisomerase III [Bacillus badius].	38.89	342	194	5	48	385	245	575	3e-62	226
rs:WP_043926749	DNA topoisomerase III [Bacillus licheniformis].	35.77	411	250	7	19	425	226	626	3e-62	226
rs:WP_000047309	DNA topoisomerase III [Bacillus thuringiensis].	35.65	359	222	5	48	401	245	599	4e-62	226
rs:WP_031516833	DNA topoisomerase III [Desulfotomaculum alkaliphilum].	34.98	426	252	9	17	425	209	626	4e-62	227
rs:WP_001235767	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	245	654	4e-62	226
rs:WP_001235760	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	245	654	4e-62	226
rs:WP_000047310	DNA topoisomerase III [Bacillus cereus].	35.65	359	222	5	48	401	245	599	4e-62	226
rs:WP_040072224	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	245	654	4e-62	226
rs:WP_001235773	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	31.96	438	274	6	36	459	246	673	4e-62	226
tr:F2LSE5_BURGS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	38.18	385	223	7	35	407	258	639	4e-62	226
rs:WP_041101489	DNA topoisomerase III [Bacillus badius].	38.89	342	194	5	48	385	245	575	4e-62	226
rs:WP_004627448	DNA topoisomerase III, bacteria and conjugative plasmid [[Clostridium] termitidis].	36.22	392	239	5	47	435	244	627	4e-62	226
gpu:KP795710_16	DNA topoisomerase III [Vibrio sp. FF_273]	31.92	495	267	9	26	459	238	723	4e-62	226
rs:WP_031598690	DNA topoisomerase III [Ferrovum myxofaciens].	35.21	426	249	9	38	459	241	643	4e-62	225
rs:WP_001482238	DNA topoisomerase III family protein [Escherichia coli].	32.14	420	262	6	37	443	245	654	4e-62	225
rs:WP_017097009	hypothetical protein [Vibrio tasmaniensis].	29.38	497	276	7	31	459	241	730	4e-62	226
rs:WP_040121204	DNA topoisomerase III [Salmonella enterica].	32.14	420	262	6	37	443	245	654	5e-62	225
rs:WP_016107448	DNA topoisomerase 3 [Bacillus cereus].	35.65	359	222	5	48	401	245	599	5e-62	226
rs:WP_015058978	Topo3 [Escherichia coli].	32.14	420	262	6	37	443	245	654	5e-62	225
rs:WP_001565875	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	245	654	5e-62	225
rs:WP_003542029	DNA topoisomerase III [Desulfotomaculum nigrificans].	34.77	417	255	7	40	452	239	642	5e-62	226
rs:WP_001550443	DNA topoisomerase III family protein [Escherichia coli].	32.14	420	262	6	37	443	245	654	5e-62	225
rs:WP_001478770	DNA topoisomerase III family protein [Escherichia coli].	32.14	420	262	6	37	443	245	654	5e-62	225
rs:WP_011282367	TraE-like protein [Haemophilus influenzae].	32.25	431	264	8	38	458	251	663	5e-62	226
rs:WP_021167107	DNA topoisomerase 3 [Sporomusa ovata].	36.51	367	209	6	38	394	235	587	5e-62	225
rs:WP_001401828	DNA topoisomerase III family protein [Escherichia coli].	32.14	420	262	6	37	443	245	654	5e-62	225
rs:WP_005596770	DNA topoisomerase III [Vibrio scophthalmi].	33.86	443	265	10	22	459	238	657	5e-62	224
rs:WP_001235747	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	32.14	420	262	6	37	443	245	654	5e-62	225
rs:WP_001576902	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	245	654	5e-62	225
rs:WP_033560648	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	245	654	5e-62	225
rs:WP_046057448	MULTISPECIES: DNA topoisomerase III [Clostridium].	35.63	348	214	3	46	391	242	581	5e-62	225
tr:X7RGR9_VIBPH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.63	489	280	5	35	459	259	742	5e-62	226
rs:WP_033883715	DNA topoisomerase III [Bacillus subtilis].	36.83	372	225	6	40	406	237	603	6e-62	225
rs:WP_033804686	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	245	654	6e-62	225
rs:WP_001235746	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	32.14	420	262	6	37	443	245	654	6e-62	225
rs:WP_017725889	hypothetical protein [Bacillus ligniniphilus].	34.61	393	238	6	18	406	223	600	6e-62	225
rs:WP_044067990	DNA topoisomerase III, partial [Escherichia coli].	39.04	292	170	3	94	385	1	284	6e-62	216
rs:WP_035379522	DNA topoisomerase III, partial [Fervidicella metallireducens].	34.44	363	222	5	36	393	233	584	6e-62	223
rs:WP_015059104	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	245	654	6e-62	225
rs:WP_032221747	DNA topoisomerase III, partial [Escherichia coli].	32.14	420	262	6	37	443	221	630	6e-62	224
tr:A0A0C5PL74_SHIFL	SubName: Full=Strain 072 plasmid pSF07202, complete sequence {ECO:0000313|EMBL:AJQ17353.1};	32.14	420	262	6	37	443	209	618	6e-62	224
rs:WP_042098135	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	245	654	6e-62	225
rs:WP_016647531	DNA topoisomerase III [Campylobacter ureolyticus].	31.28	438	283	9	33	459	234	664	6e-62	225
rs:WP_047225405	DNA topoisomerase III [Bacillus thuringiensis].	35.56	360	221	6	48	401	245	599	6e-62	225
rs:WP_020997000	DNA topoisomerase III, partial [[Haemophilus] parasuis].	38.91	293	171	2	36	328	252	536	6e-62	221
rs:WP_044344485	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	245	654	6e-62	225
rs:WP_045644513	DNA topoisomerase III [Peptococcaceae bacterium BRH_c4b].	34.70	415	256	9	36	446	235	638	7e-62	224
rs:WP_042770153	DNA topoisomerase III [Vibrio parahaemolyticus].	28.63	489	280	5	35	459	245	728	7e-62	225
rs:WP_039073230	DNA topoisomerase III [Bacillus sp. MSP5.4].	35.52	411	251	7	19	425	226	626	7e-62	225
rs:WP_005430719	DNA topoisomerase III [Vibrio campbellii].	30.44	450	280	8	26	459	238	670	7e-62	225
rs:WP_021544332	hypothetical protein [Escherichia coli].	32.14	420	262	6	37	443	245	654	7e-62	225
tr:C3AGX8_BACMY	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	35.46	361	222	6	39	393	236	591	7e-62	223
rs:WP_021526210	hypothetical protein [Escherichia coli].	32.14	420	262	6	37	443	245	654	7e-62	225
rs:WP_011053526	hypothetical protein [Haemophilus influenzae].	32.48	431	263	8	38	458	251	663	7e-62	225
rs:WP_001694195	DNA topoisomerase III family protein [Escherichia coli].	32.14	420	262	6	37	443	245	654	7e-62	225
rs:WP_000047301	DNA topoisomerase III [Bacillus cereus].	35.56	360	221	6	48	401	245	599	7e-62	225
rs:WP_000047299	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	35.56	360	221	6	48	401	245	599	7e-62	225
rs:WP_016133523	DNA topoisomerase 3 [Bacillus cereus].	34.02	388	247	5	19	401	216	599	7e-62	225
rs:WP_032195778	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	245	654	7e-62	225
rs:WP_001714225	DNA topoisomerase III [Salmonella enterica].	32.14	420	262	6	37	443	245	654	7e-62	225
rs:WP_000047306	DNA topoisomerase III [Bacillus cereus].	35.65	359	222	5	48	401	245	599	8e-62	225
rs:WP_000047305	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	35.65	359	222	5	48	401	245	599	8e-62	225
rs:WP_000047298	DNA topoisomerase III [Bacillus cereus].	35.56	360	221	6	48	401	245	599	8e-62	225
rs:WP_048355434	DNA topoisomerase III [Bacillus sp. GO-13].	35.59	413	248	8	19	425	216	616	8e-62	225
rs:WP_024700499	DNA topoisomerase III [Vibrio parahaemolyticus].	28.83	489	279	5	35	459	245	728	8e-62	225
rs:WP_026821966	DNA topoisomerase III [Arsenophonus nasoniae].	34.19	351	223	3	36	386	252	594	8e-62	223
rs:WP_000047307	DNA topoisomerase III [Bacillus cereus].	35.65	359	222	5	48	401	245	599	8e-62	225
rs:WP_042987872	DNA topoisomerase III [Vibrio cholerae].	31.99	447	272	6	30	458	240	672	8e-62	225
rs:WP_021526654	hypothetical protein [Escherichia coli].	32.14	420	262	6	37	443	245	654	8e-62	224
tr:A0A0F4VZX4_9CLOT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KJZ86815.1};	35.63	348	214	3	46	391	269	608	9e-62	225
tr:A0A078BN72_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	34.04	426	256	7	38	459	241	645	9e-62	224
rs:WP_000047296	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	35.56	360	221	6	48	401	245	599	9e-62	224
tr:F7NDM8_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	34.84	419	250	8	32	435	229	639	9e-62	224
tr:C2Q4N3_BACCE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	35.39	373	230	6	36	401	235	603	9e-62	225
rs:WP_014186245	DNA topoisomerase III [Desulfosporosinus orientis].	35.22	389	231	6	56	435	252	628	9e-62	224
rs:WP_044074388	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	245	654	9e-62	224
rs:WP_001235750	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	32.14	420	262	6	37	443	245	654	9e-62	224
rs:WP_021534058	hypothetical protein [Escherichia coli].	31.89	417	267	5	37	443	245	654	9e-62	224
rs:WP_001235745	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	32.14	420	262	6	37	443	245	654	1e-61	224
rs:WP_046179383	DNA topoisomerase III [Domibacillus sp. PAMC 80007].	35.53	380	231	7	28	401	228	599	1e-61	224
rs:WP_002140241	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	35.39	373	230	6	36	401	231	599	1e-61	224
rs:WP_001505439	DNA topoisomerase III family protein [Escherichia coli].	32.14	420	262	6	37	443	245	654	1e-61	224
rs:WP_044739928	DNA topoisomerase III [Bacillus mycoides].	36.21	359	220	5	48	401	245	599	1e-61	224
rs:WP_034169408	DNA topoisomerase III [Escherichia coli].	32.70	419	262	6	37	443	245	655	1e-61	224
rs:WP_020311915	DNA topoisomerase III [Megasphaera sp. NM10].	34.19	427	252	9	30	445	238	646	1e-61	224
rs:WP_016079170	DNA topoisomerase 3 [Bacillus cereus].	34.61	393	243	6	48	435	245	628	1e-61	224
rs:WP_000047282	DNA topoisomerase III [Bacillus cereus].	35.38	359	223	5	48	401	245	599	1e-61	224
rs:WP_032346759	DNA topoisomerase III [Escherichia coli].	31.89	417	267	5	37	443	245	654	1e-61	224
rs:WP_032181595	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	245	654	1e-61	224
tr:R9NHH5_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	37.94	311	188	3	36	344	242	549	1e-61	221
rs:WP_002091243	DNA topoisomerase III [Bacillus cereus].	35.39	373	230	6	36	401	231	599	1e-61	224
rs:WP_029865550	DNA topoisomerase III [Vibrio parahaemolyticus].	28.83	489	279	5	35	459	245	728	1e-61	224
rs:WP_000047304	DNA topoisomerase III [Bacillus cereus].	35.38	359	223	5	48	401	245	599	1e-61	224
rs:WP_026592563	DNA topoisomerase III [Bacillus sp. UNC437CL72CviS29].	33.33	411	250	8	36	435	231	628	1e-61	224
rs:WP_002124971	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	35.39	373	230	6	36	401	231	599	1e-61	224
rs:WP_000047302	DNA topoisomerase III [Bacillus cereus].	35.38	359	223	5	48	401	245	599	1e-61	224
rs:WP_015058228	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	245	654	1e-61	224
rs:WP_000047303	DNA topoisomerase III [Bacillus cereus].	35.65	359	222	5	48	401	245	599	1e-61	224
rs:WP_002115767	DNA topoisomerase III [Bacillus cereus].	35.93	359	221	5	48	401	245	599	1e-61	224
rs:WP_030022716	DNA topoisomerase III [Bacillus thuringiensis].	34.01	394	244	7	48	435	245	628	1e-61	224
rs:WP_028603717	hypothetical protein [Ottowia thiooxydans].	34.44	421	244	8	30	435	264	667	1e-61	223
rs:WP_036153519	DNA topoisomerase III [Lysinibacillus odysseyi].	38.40	362	209	8	48	401	244	599	1e-61	224
tr:C2SEV4_BACCE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	35.39	373	230	6	36	401	235	603	1e-61	224
rs:WP_024127756	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	245	654	1e-61	224
tr:C2XNU9_BACCE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	35.39	373	230	6	36	401	235	603	1e-61	224
rs:WP_016097005	DNA topoisomerase 3 [Bacillus cereus].	35.39	373	230	6	36	401	231	599	1e-61	224
rs:WP_040465856	DNA topoisomerase III, partial [Erwinia tracheiphila].	37.94	311	188	3	36	344	242	549	1e-61	221
rs:WP_045348202	DNA topoisomerase III [Enterobacter cloacae].	33.04	451	268	10	27	459	239	673	1e-61	225
rs:WP_029397051	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	245	654	1e-61	224
rs:WP_033706351	DNA topoisomerase III [Bacillus cereus].	35.39	373	230	6	36	401	231	599	1e-61	224
rs:WP_040101183	DNA topoisomerase III, partial [Escherichia coli].	31.90	420	263	6	37	443	110	519	1e-61	221
tr:V1URM1_SALET	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESG40303.1};	39.19	273	160	2	127	399	3	269	1e-61	213
rs:WP_045418085	DNA topoisomerase III [Vibrio owensii].	30.80	448	279	9	26	459	238	668	1e-61	224
rs:WP_001129908	DNA topoisomerase III [Bacillus cereus].	36.21	359	220	5	48	401	245	599	1e-61	224
rs:WP_042080259	DNA topoisomerase III, partial [Escherichia coli].	35.69	339	199	4	98	436	1	320	1e-61	215
rs:WP_039842175	DNA topoisomerase III [Vibrio owensii].	30.75	452	276	9	26	459	238	670	1e-61	224
rs:WP_033674455	DNA topoisomerase III [Bacillus gaemokensis].	34.78	368	231	5	39	401	236	599	1e-61	224
rs:WP_046597968	DNA topoisomerase III [Salmonella enterica].	32.14	420	262	6	37	443	245	654	1e-61	224
rs:WP_045147076	DNA topoisomerase III [Escherichia coli].	32.46	419	263	6	37	443	245	655	2e-61	224
rs:WP_001423372	DNA topoisomerase III family protein [Escherichia coli].	32.14	420	262	6	37	443	245	654	2e-61	224
rs:WP_000047290	DNA topoisomerase III [Bacillus cereus].	35.28	360	222	6	48	401	245	599	2e-61	224
rs:WP_032312320	DNA topoisomerase III, partial [Escherichia coli].	31.90	420	263	6	37	443	135	544	2e-61	222
rs:WP_016128273	DNA topoisomerase 3 [Bacillus cereus].	36.21	359	220	5	48	401	245	599	2e-61	224
rs:WP_001235753	DNA topoisomerase III [Salmonella enterica].	32.14	420	262	6	37	443	245	654	2e-61	224
rs:WP_000047300	MULTISPECIES: DNA topoisomerase III [Bacillus].	35.28	360	222	6	48	401	245	599	2e-61	224
rs:WP_032716084	DNA topoisomerase III [Enterobacter aerogenes].	31.92	448	273	8	28	459	240	671	2e-61	224
rs:WP_040215770	DNA topoisomerase III, partial [Klebsiella pneumoniae].	31.85	449	276	8	27	459	239	673	2e-61	224
rs:WP_001129907	DNA topoisomerase III [Bacillus cereus].	36.21	359	220	5	48	401	245	599	2e-61	224
rs:WP_031942367	DNA topoisomerase III [Escherichia coli].	31.90	420	263	6	37	443	174	583	2e-61	223
tr:A0A017RV88_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.93	410	253	7	36	434	233	631	2e-61	223
rs:WP_001235774	hypothetical protein, partial [Escherichia coli].	31.85	449	276	8	27	459	239	673	2e-61	223
rs:WP_025732981	DNA topoisomerase III [Carnimonas nigrificans].	34.85	373	223	3	21	384	232	593	2e-61	223
rs:WP_001429160	DNA topoisomerase III family protein [Escherichia coli].	32.14	420	262	6	37	443	245	654	2e-61	224
rs:WP_001235752	DNA topoisomerase III [Salmonella enterica].	32.14	420	262	6	37	443	245	654	2e-61	224
rs:WP_036145124	DNA topoisomerase III [Lysinibacillus sp. BF-4].	36.65	382	223	7	23	396	222	592	2e-61	223
rs:WP_025367771	DNA topoisomerase III [Klebsiella pneumoniae].	32.07	449	275	8	27	459	239	673	2e-61	224
rs:WP_006638741	DNA topoisomerase III [Bacillus sonorensis].	35.55	391	235	4	19	401	216	597	2e-61	224
rs:WP_001235756	DNA topoisomerase III [Escherichia coli].	31.90	420	263	6	37	443	245	654	2e-61	223
rs:WP_032881471	DNA topoisomerase III [Pseudomonas sp. BRG-100].	33.98	412	260	4	31	432	236	645	2e-61	223
rs:WP_025789617	DNA topoisomerase III [Vibrio parahaemolyticus].	30.71	495	275	8	27	459	239	727	2e-61	224
rs:WP_025693453	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	245	654	2e-61	223
tr:A0A098F5K3_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	34.66	401	248	6	40	435	238	629	2e-61	222
rs:WP_001689493	DNA topoisomerase, partial [Escherichia coli].	32.22	419	264	6	37	443	130	540	3e-61	221
rs:WP_001235736	DNA topoisomerase III [Escherichia coli].	31.90	420	263	6	37	443	245	654	3e-61	223
rs:WP_000047318	DNA topoisomerase III [Bacillus cereus].	35.38	359	223	5	48	401	245	599	3e-61	223
rs:WP_000047308	DNA topoisomerase III [Bacillus cereus].	35.65	359	222	5	48	401	245	599	3e-61	223
rs:WP_015263775	DNA topoisomerase III [Desulfitobacterium dichloroeliminans].	34.92	398	244	5	36	428	233	620	3e-61	223
rs:WP_001990567	MULTISPECIES: DNA topoisomerase 3 [Bacillus cereus group].	33.76	388	248	5	19	401	216	599	3e-61	223
rs:WP_032739622	DNA topoisomerase III, partial [Klebsiella pneumoniae].	39.59	293	167	4	94	385	1	284	3e-61	214
rs:WP_025789167	DNA topoisomerase III [Vibrio parahaemolyticus].	28.63	489	280	5	35	459	245	728	3e-61	223
rs:WP_000047283	DNA topoisomerase III [Bacillus cereus].	33.76	388	248	5	19	401	216	599	3e-61	223
rs:WP_042981626	DNA topoisomerase III [Bacillus mycoides].	35.05	368	230	5	39	401	236	599	3e-61	223
rs:WP_017762755	DNA topoisomerase III [Bacillus thuringiensis].	35.38	359	223	5	48	401	245	599	3e-61	223
rs:WP_032341387	DNA topoisomerase III [Escherichia coli].	31.89	417	267	6	37	443	245	654	3e-61	223
rs:WP_000047320	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	35.38	359	223	5	48	401	245	599	3e-61	223
rs:WP_031410708	DNA topoisomerase III [Vibrio parahaemolyticus].	28.22	489	282	4	35	459	245	728	3e-61	223
rs:WP_024236378	DNA topoisomerase III [Escherichia coli].	31.90	420	263	6	37	443	245	654	3e-61	223
rs:WP_001436419	DNA topoisomerase III family protein [Escherichia coli].	32.14	420	262	6	37	443	245	654	3e-61	223
rs:WP_015059067	DNA topoisomerase III [Escherichia coli].	33.70	451	265	10	27	459	239	673	4e-61	224
rs:WP_031855974	DNA topoisomerase III [Vibrio parahaemolyticus].	29.04	489	278	6	35	459	245	728	4e-61	223
rs:WP_000047289	DNA topoisomerase III [Bacillus cereus].	33.76	388	248	5	19	401	216	599	4e-61	223
rs:WP_001235737	DNA topoisomerase III [Salmonella enterica].	31.90	420	263	6	37	443	245	654	4e-61	223
rs:WP_042840071	DNA topoisomerase III [Salmonella enterica].	31.90	420	263	6	37	443	245	654	4e-61	223
rs:WP_044784126	DNA topoisomerase III [Bacillus thuringiensis].	35.38	359	223	5	48	401	245	599	4e-61	223
rs:WP_016089486	DNA topoisomerase 3 [Bacillus cereus].	33.76	388	248	5	19	401	216	599	4e-61	223
rs:WP_042897089	DNA topoisomerase III, partial [Enterobacter aerogenes].	33.33	450	266	9	27	458	214	647	4e-61	223
rs:WP_000047297	DNA topoisomerase III [Bacillus cereus].	35.28	360	222	6	48	401	245	599	4e-61	223
rs:WP_029441506	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	35.00	360	223	6	48	401	245	599	4e-61	223
rs:WP_001773473	DNA topoisomerase III [Escherichia coli].	33.33	450	266	10	27	458	239	672	4e-61	223
rs:WP_016837347	DNA topoisomerase III [Ureibacillus thermosphaericus].	34.86	393	242	7	48	435	244	627	4e-61	223
rs:WP_046958857	DNA topoisomerase III [Bacillus cereus].	33.76	388	248	5	19	401	216	599	4e-61	223
rs:WP_000047288	DNA topoisomerase III [Bacillus cereus].	33.76	388	248	5	19	401	216	599	4e-61	223
rs:WP_000047286	DNA topoisomerase III [Bacillus cereus].	35.00	360	223	6	48	401	245	599	5e-61	223
rs:WP_000047265	DNA topoisomerase III [Bacillus cereus].	33.76	388	248	5	19	401	216	599	5e-61	223
rs:WP_000047279	DNA topoisomerase III [Bacillus cereus].	35.00	360	223	6	48	401	245	599	5e-61	223
rs:WP_000047287	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	35.00	360	223	6	48	401	245	599	5e-61	223
rs:WP_000047280	DNA topoisomerase III [Bacillus thuringiensis].	35.00	360	223	6	48	401	245	599	5e-61	223
rs:WP_034288008	DNA topoisomerase III [Helicobacter sp. MIT 11-5569].	32.89	447	268	12	32	459	235	668	5e-61	223
rs:WP_025115491	DNA topoisomerase III [Lysinibacillus fusiformis].	36.97	376	222	8	28	396	228	595	5e-61	223
rs:WP_023520977	DNA topoisomerase III [Bacillus thuringiensis].	35.00	360	223	6	48	401	245	599	5e-61	223
rs:WP_024983039	DNA topoisomerase III [Brevibacillus borstelensis].	36.54	364	222	5	38	396	236	595	5e-61	223
rs:WP_001140200	DNA topoisomerase III [Bacillus thuringiensis].	34.72	360	224	6	48	401	245	599	5e-61	223
rs:WP_032114974	DNA topoisomerase III [Arsenophonus endosymbiont of Nilaparvata lugens].	35.33	351	219	3	36	386	252	594	5e-61	221
rs:WP_032331421	DNA topoisomerase III [Escherichia coli].	32.13	417	266	5	37	443	245	654	5e-61	223
rs:WP_000047321	DNA topoisomerase III [Bacillus cereus].	35.38	359	223	5	48	401	245	599	5e-61	223
rs:WP_035311086	DNA topoisomerase III [Clostridium sp. HMP27].	33.33	411	256	9	32	435	229	628	5e-61	223
rs:WP_045424446	DNA topoisomerase III [Vibrio jasicida].	30.00	450	282	8	26	459	238	670	5e-61	223
rs:WP_003562019	DNA topoisomerase III family protein [Escherichia coli].	32.14	420	262	6	37	443	245	654	5e-61	222
rs:WP_009767084	DNA topoisomerase [Moraxella macacae].	30.82	425	268	7	36	446	249	661	6e-61	223
rs:WP_024221956	DNA topoisomerase III [Escherichia coli].	32.35	408	259	5	37	432	245	647	6e-61	222
rs:WP_040209776	DNA topoisomerase III [Klebsiella pneumoniae].	31.85	449	276	8	27	459	239	673	6e-61	223
rs:WP_004199098	MULTISPECIES: DNA topoisomerase III [Bacteria].	31.85	449	276	8	27	459	239	673	6e-61	223
rs:WP_021537783	hypothetical protein [Escherichia coli].	32.22	419	264	6	37	443	245	655	6e-61	222
rs:WP_048231795	DNA topoisomerase III, partial [Escherichia coli].	33.25	415	257	6	37	439	245	651	6e-61	221
tr:F2F8B2_SOLSS	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	36.10	374	229	5	28	397	230	597	6e-61	223
rs:WP_046953758	DNA topoisomerase III [Bacillus cereus].	35.38	359	223	5	48	401	245	599	6e-61	223
rs:WP_025150533	DNA topoisomerase III [Bacillus sp. H1a].	35.93	359	221	5	48	401	245	599	6e-61	223
rs:WP_040120508	DNA topoisomerase III [Klebsiella pneumoniae].	31.85	449	276	8	27	459	239	673	6e-61	223
rs:WP_038994990	DNA topoisomerase III [Escherichia coli].	31.65	417	268	5	37	443	245	654	6e-61	222
rs:WP_041865800	DNA topoisomerase III [Solibacillus silvestris].	36.10	374	229	5	28	397	227	594	6e-61	222
rs:WP_028672238	DNA topoisomerase III [Saccharospirillum impatiens].	38.33	347	196	5	35	371	250	588	6e-61	221
tr:A0A078M9U1_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	36.39	382	224	7	23	396	222	592	6e-61	222
rs:WP_008404653	DNA topoisomerase III [Bacillus isronensis].	36.10	374	229	5	28	397	227	594	6e-61	222
rs:WP_043937735	MULTISPECIES: DNA topoisomerase III [Bacillus].	35.00	360	223	6	48	401	245	599	6e-61	222
rs:WP_008824610	DNA topoisomerase III [Haloplasma contractile].	32.02	381	238	5	20	397	226	588	6e-61	222
rs:WP_039575838	DNA topoisomerase III, partial [Xanthomonas axonopodis].	38.10	336	195	6	47	375	1	330	6e-61	213
rs:WP_031942376	DNA topoisomerase III [Escherichia coli].	31.90	420	263	6	37	443	245	654	6e-61	222
rs:WP_001235751	DNA topoisomerase III [Escherichia coli].	31.90	420	263	6	37	443	245	654	6e-61	222
rs:WP_040104610	DNA topoisomerase III [Salinicoccus roseus].	35.86	382	225	7	28	405	227	592	7e-61	222
rs:WP_016770543	DNA topoisomerase [Salmonella enterica].	31.89	417	267	5	37	443	245	654	7e-61	222
rs:WP_048375505	DNA topoisomerase III [Bacillus sp. LK2].	35.93	359	221	5	48	401	245	599	7e-61	222
rs:WP_002174671	DNA topoisomerase III [Bacillus cereus].	35.93	359	221	5	48	401	245	599	7e-61	222
rs:WP_039086231	conjugal transfer protein TraE [Gallibacterium anatis].	31.79	431	266	8	38	458	251	663	7e-61	223
rs:WP_012291470	topoisomerase IA [Escherichia coli].	31.90	420	263	6	37	443	245	654	7e-61	222
rs:WP_042876255	DNA topoisomerase III, partial [Bacillus cereus].	33.33	387	251	4	19	401	110	493	7e-61	220
rs:WP_001235738	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	245	654	7e-61	222
rs:WP_040118351	DNA topoisomerase III [Pectobacterium atrosepticum].	33.41	428	256	7	31	432	245	669	7e-61	222
rs:WP_024234184	DNA topoisomerase III [Escherichia coli].	31.90	420	263	6	37	443	245	654	8e-61	222
rs:WP_016716345	DNA topoisomerase 3 [Bacillus cereus].	33.51	388	249	5	19	401	216	599	8e-61	222
rs:WP_027623839	DNA topoisomerase III [Clostridium lundense].	35.97	367	206	8	40	391	237	589	8e-61	222
rs:WP_001235755	DNA topoisomerase III [Escherichia coli].	31.65	417	268	5	37	443	245	654	8e-61	222
rs:WP_032180613	DNA topoisomerase III [Escherichia coli].	31.90	420	263	6	37	443	245	654	8e-61	222
tr:A6CP00_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	34.00	403	247	10	32	426	224	615	8e-61	222
rs:WP_002139479	DNA topoisomerase III [Bacillus cereus].	35.12	373	231	6	36	401	231	599	8e-61	222
rs:WP_002159436	DNA topoisomerase III [Bacillus cereus].	35.12	373	231	6	36	401	231	599	8e-61	222
rs:WP_001140202	DNA topoisomerase III [Bacillus cereus].	35.38	359	223	5	48	401	245	599	8e-61	222
rs:WP_016234218	DNA topoisomerase III [Escherichia coli].	32.14	420	262	6	37	443	245	654	8e-61	222
sp:TOP3_BACC1	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	33.51	388	249	5	19	401	216	599	8e-61	222
rs:WP_044022747	DNA topoisomerase III [Bacillus sp. SG-1].	34.00	403	247	10	32	426	229	620	9e-61	222
rs:WP_011639937	DNA topoisomerase III [Syntrophomonas wolfei].	34.68	395	237	7	39	425	233	614	9e-61	221
rs:WP_001235762	DNA topoisomerase III [Escherichia coli].	31.89	417	267	5	37	443	245	654	9e-61	222
rs:WP_039052484	DNA topoisomerase III [Escherichia coli].	31.89	417	267	5	37	443	245	654	9e-61	222
rs:WP_001235748	DNA topoisomerase III [Escherichia coli].	32.13	417	266	5	37	443	245	654	9e-61	222
rs:WP_000047284	DNA topoisomerase III [Bacillus cereus].	33.51	388	249	5	19	401	216	599	9e-61	222
rs:WP_040084152	DNA topoisomerase III [Escherichia coli].	31.90	420	263	6	37	443	245	654	9e-61	222
rs:WP_017111690	hypothetical protein [Vibrio tasmaniensis].	29.93	441	277	7	36	459	246	671	9e-61	222
sp:TOP3_BACAH	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	33.51	388	249	5	19	401	216	599	9e-61	222
rs:WP_000765173	DNA topoisomerase III [Escherichia coli].	32.11	408	260	5	37	432	245	647	1e-60	222
rs:WP_034440480	DNA topoisomerase III [Candidatus Clostridium anorexicamassiliense].	35.81	363	218	6	36	391	232	586	1e-60	222
rs:WP_000047281	DNA topoisomerase III [Bacillus cereus].	35.00	360	223	6	48	401	245	599	1e-60	222
rs:WP_026695925	DNA topoisomerase III [Bacillus kribbensis].	37.43	366	216	7	32	391	230	588	1e-60	222
rs:WP_000047311	DNA topoisomerase 3 [Bacillus cereus].	33.51	388	249	5	19	401	216	599	1e-60	222
rs:WP_001983848	DNA topoisomerase III [Bacillus cereus].	33.51	388	249	5	19	401	216	599	1e-60	222
rs:WP_001140207	DNA topoisomerase III [Bacillus anthracis].	33.51	388	249	5	19	401	216	599	1e-60	222
rs:WP_001140203	DNA topoisomerase III [Bacillus cereus].	33.51	388	249	5	19	401	216	599	1e-60	222
rs:WP_026574293	DNA topoisomerase III [Bacillus sp. UNC438CL73TsuS30].	34.39	410	247	9	36	435	231	628	1e-60	222
rs:WP_000047295	DNA topoisomerase III [Bacillus cereus].	35.00	360	223	6	48	401	245	599	1e-60	222
rs:WP_010966830	DNA topoisomerase III [Clostridium acetobutylicum].	34.05	373	235	6	38	404	235	602	1e-60	221
tr:C3DEJ5_BACTS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	36.55	342	203	7	69	401	5	341	1e-60	216
rs:WP_017108524	hypothetical protein [Vibrio tasmaniensis].	28.97	497	278	7	31	459	241	730	1e-60	222
rs:WP_001235743	DNA topoisomerase III [Escherichia coli].	31.90	420	263	6	37	443	245	654	1e-60	221
rs:WP_001140206	DNA topoisomerase III [Bacillus cereus].	33.51	388	249	5	19	401	216	599	1e-60	222
rs:WP_017755328	DNA topoisomerase III [Bacillus sp. ZYK].	34.07	405	240	7	47	439	245	634	1e-60	222
rs:WP_039636260	DNA topoisomerase III [Clostridium argentinense].	35.31	405	246	6	36	435	232	625	1e-60	221
rs:WP_042100636	DNA topoisomerase III [Escherichia coli].	31.90	420	263	6	37	443	245	654	1e-60	221
rs:WP_042513694	DNA topoisomerase III [Bacillus anthracis].	35.10	359	224	5	48	401	245	599	1e-60	221
rs:WP_001140212	DNA topoisomerase III [Bacillus cereus].	33.51	388	249	5	19	401	216	599	1e-60	221
rs:WP_001675950	DNA topoisomerase III [Salmonella enterica].	31.90	420	263	6	37	443	245	654	1e-60	221
rs:WP_018395581	DNA topoisomerase III [Bacillus sp. 37MA].	35.96	356	217	6	48	397	245	595	1e-60	221
rs:WP_001556719	DNA topoisomerase III [Escherichia coli].	31.90	420	263	6	37	443	245	654	1e-60	221
rs:WP_031500110	DNA topoisomerase III [Vibrio parahaemolyticus].	28.83	489	279	6	35	459	245	728	1e-60	221
rs:WP_002130832	DNA topoisomerase III [Bacillus cereus].	34.95	372	233	5	36	401	231	599	1e-60	221
rs:WP_046392322	DNA topoisomerase III [Bacillus cereus].	35.00	360	223	6	48	401	245	599	1e-60	221
rs:WP_016247728	DNA topoisomerase III [Escherichia coli].	31.90	420	263	6	37	443	245	654	1e-60	221
rs:WP_039229157	DNA topoisomerase III [Clostridium haemolyticum].	33.33	414	252	6	32	435	229	628	1e-60	221
rs:WP_037404202	MULTISPECIES: DNA topoisomerase III [Serratia].	31.85	449	276	8	27	459	239	673	1e-60	222
rs:WP_013379324	DNA topoisomerase III [Eubacterium limosum].	36.60	388	228	8	47	428	244	619	1e-60	221
rs:WP_003339104	DNA topoisomerase III [Brevibacillus laterosporus].	36.86	350	212	5	47	391	245	590	1e-60	221
rs:WP_000047323	DNA topoisomerase III [Bacillus cereus].	33.59	387	250	4	19	401	216	599	1e-60	221
rs:WP_046360976	hypothetical protein, partial [Hafnia alvei].	31.08	415	272	4	35	449	235	635	1e-60	220
rs:WP_034582848	DNA topoisomerase III [Clostridium acetobutylicum].	34.05	373	235	6	38	404	235	602	2e-60	221
rs:WP_047090416	DNA topoisomerase III [Escherichia coli].	31.90	420	263	6	37	443	245	654	2e-60	221
rs:WP_001140201	DNA topoisomerase III [Bacillus cereus].	34.72	360	224	6	48	401	245	599	2e-60	221
rs:WP_001140199	DNA topoisomerase III [Bacillus cereus].	35.00	360	223	6	48	401	245	599	2e-60	221
rs:WP_045409866	DNA topoisomerase III [Vibrio jasicida].	28.14	494	286	5	30	459	240	728	2e-60	221
rs:WP_016083678	DNA topoisomerase 3 [Bacillus cereus].	35.00	360	223	6	48	401	245	599	2e-60	221
tr:A0A078BHB1_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	35.56	419	241	11	22	434	288	683	2e-60	222
rs:WP_024235642	DNA topoisomerase III [Escherichia coli].	31.90	420	263	6	37	443	245	654	2e-60	221
rs:WP_003335207	DNA topoisomerase III [Brevibacillus laterosporus].	36.86	350	212	5	47	391	245	590	2e-60	221
rs:WP_031500043	DNA topoisomerase III [Vibrio parahaemolyticus].	28.63	489	280	5	35	459	245	728	2e-60	221
rs:WP_024236815	DNA topoisomerase III [Escherichia coli].	31.90	420	263	6	37	443	245	654	2e-60	221
rs:WP_025117795	DNA topoisomerase III [Bacillus sp. H1m].	34.72	360	224	6	48	401	245	599	2e-60	221
tr:A0A090RXB4_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	39.78	274	158	2	36	309	28	294	2e-60	211
rs:WP_001567310	DNA topoisomerase III [Escherichia coli].	31.90	420	263	6	37	443	245	654	2e-60	221
rs:WP_005638126	conjugal transfer protein TraE [Haemophilus haemolyticus].	32.48	431	263	8	38	458	251	663	2e-60	221
rs:WP_012477155	DNA topoisomerase III [Salmonella enterica].	31.90	420	263	6	37	443	245	654	2e-60	221
rs:WP_048267054	DNA topoisomerase III [Escherichia coli].	32.70	419	262	6	37	443	245	655	2e-60	221
rs:WP_001677783	DNA topoisomerase III family protein [Escherichia coli].	31.67	420	264	6	37	443	245	654	2e-60	221
rs:WP_044504807	DNA topoisomerase III [Megasphaera sp. NP3].	33.55	456	265	12	23	459	229	665	2e-60	221
rs:WP_017513957	DNA topoisomerase III, partial [beta proteobacterium FWI2].	38.01	292	179	2	36	325	241	532	2e-60	217
rs:WP_001140205	DNA topoisomerase III [Bacillus cereus].	34.72	360	224	6	48	401	245	599	2e-60	221
rs:WP_016117101	DNA topoisomerase 3 [Bacillus cereus].	34.72	360	224	6	48	401	245	599	2e-60	221
rs:WP_006916694	DNA topoisomerase III [Bacillus sp. GeD10].	34.72	360	224	6	48	401	245	599	2e-60	221
rs:WP_033695435	DNA topoisomerase III [Bacillus weihenstephanensis].	34.72	360	224	6	48	401	245	599	2e-60	221
rs:WP_029103745	hypothetical protein [Moraxella caprae].	32.43	441	278	7	36	458	247	685	2e-60	221
rs:WP_021542872	hypothetical protein [Escherichia coli].	33.26	451	267	10	27	459	239	673	2e-60	221
rs:WP_001419801	DNA topoisomerase III family protein [Escherichia coli].	31.89	417	267	5	37	443	245	654	2e-60	221
rs:WP_012662275	DNA topoisomerase III [Campylobacter lari].	31.63	449	274	10	33	459	235	672	2e-60	220
rs:WP_031411082	DNA topoisomerase III [Brevibacillus laterosporus].	36.57	350	213	5	47	391	245	590	2e-60	221
rs:WP_040047798	DNA topoisomerase III [Bacillaceae bacterium MTCC 8252].	36.95	341	202	4	48	385	245	575	2e-60	221
rs:WP_044307355	DNA topoisomerase III [Bacillus cereus].	34.72	360	224	6	48	401	245	599	2e-60	221
sp:TOP3_BACCZ	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	33.51	388	249	5	19	401	216	599	2e-60	221
rs:WP_012064441	DNA topoisomerase III [Alkaliphilus metalliredigens].	33.75	400	252	6	40	435	237	627	2e-60	221
rs:WP_045719108	DNA topoisomerase III, partial [Salmonella enterica].	38.89	288	168	3	98	385	1	280	2e-60	212
rs:WP_032429271	hypothetical protein, partial [Klebsiella pneumoniae].	32.05	443	274	5	29	459	237	664	2e-60	221
rs:WP_017561464	DNA topoisomerase III [Bacillus cereus].	33.16	389	249	6	19	401	216	599	2e-60	221
tr:A0A0F5I3C4_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KKB40169.1};	36.95	341	202	4	48	385	256	586	3e-60	221
rs:WP_000047278	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	34.72	360	224	6	48	401	245	599	3e-60	221
rs:WP_016097640	DNA topoisomerase 3 [Bacillus cereus].	34.72	360	224	6	48	401	245	599	3e-60	221
rs:WP_000047291	MULTISPECIES: DNA topoisomerase 3 [Bacillus cereus group].	35.00	360	223	6	48	401	245	599	3e-60	221
rs:WP_026944559	DNA topoisomerase III [Helicobacter rodentium].	32.66	447	269	12	32	459	235	668	3e-60	221
rs:WP_001140210	DNA topoisomerase 3 [Bacillus thuringiensis].	33.25	388	250	5	19	401	216	599	3e-60	221
rs:WP_044599622	DNA topoisomerase III [Campylobacter peloridis].	31.40	449	275	10	33	459	235	672	3e-60	219
rs:WP_036171005	DNA topoisomerase III [Lysinibacillus massiliensis].	36.84	361	216	7	48	401	244	599	3e-60	220
rs:WP_045467535	DNA topoisomerase III [Burkholderiales bacterium GJ-E10].	33.95	430	251	11	37	459	240	643	3e-60	220
rs:WP_032490885	topoisomerase [Yersinia enterocolitica].	32.94	425	262	6	31	432	245	669	3e-60	221
rs:WP_000241072	DNA topoisomerase III [Bacillus cereus].	33.76	388	248	5	19	401	216	599	3e-60	220
rs:WP_002113637	DNA topoisomerase III [Bacillus cereus].	34.85	373	232	6	36	401	231	599	3e-60	220
rs:WP_026563023	DNA topoisomerase III [Bacillus sp. J37].	35.20	375	226	8	28	396	228	591	3e-60	220
rs:WP_042061035	DNA topoisomerase III [Escherichia coli].	33.11	453	265	11	27	459	239	673	3e-60	221
rs:WP_044527626	DNA topoisomerase III [Escherichia coli].	31.86	408	261	5	37	432	245	647	3e-60	220
rs:WP_001549937	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	33.48	451	266	10	27	459	239	673	3e-60	221
gp:AP014864_5696	DNA topoisomerase III [Bacillus thuringiensis serovar tolworthi]	34.72	360	224	6	48	401	245	599	3e-60	220
rs:WP_038261253	DNA topoisomerase III [[Clostridium] litorale].	33.17	416	248	8	19	425	223	617	3e-60	220
rs:WP_016103425	DNA topoisomerase 3 [Bacillus cereus].	34.85	373	232	6	36	401	231	599	3e-60	220
rs:WP_031622287	DNA topoisomerase III [Salmonella enterica].	31.89	417	267	5	37	443	245	654	4e-60	220
rs:WP_000241071	DNA topoisomerase III [Bacillus cereus].	34.78	368	231	5	39	401	236	599	4e-60	220
rs:WP_003388716	DNA topoisomerase III [Brevibacillus borstelensis].	36.09	363	225	4	38	396	236	595	4e-60	220
tr:F7ML35_CLOBO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.33	414	252	6	32	435	229	628	4e-60	220
rs:WP_032325884	DNA topoisomerase III [Escherichia coli].	31.67	420	264	6	37	443	245	654	4e-60	220
rs:WP_002169258	DNA topoisomerase III [Bacillus cereus].	33.72	427	254	10	17	435	223	628	4e-60	220
rs:WP_021515666	hypothetical protein [Escherichia coli].	31.89	417	267	5	37	443	245	654	4e-60	220
rs:WP_002151617	DNA topoisomerase III [Bacillus cereus].	34.85	373	232	6	36	401	231	599	4e-60	220
rs:WP_034316017	DNA topoisomerase III [Bacillus simplex].	34.16	401	250	6	40	435	238	629	4e-60	220
rs:WP_046617322	DNA topoisomerase III [Salmonella enterica].	32.38	420	261	6	37	443	245	654	4e-60	220
rs:WP_036734273	DNA topoisomerase III [Peptococcaceae bacterium SCADC1_2_3].	34.74	403	244	9	31	428	229	617	5e-60	219
rs:WP_016125362	DNA topoisomerase 3 [Bacillus cereus].	34.72	360	224	6	48	401	245	599	5e-60	220
rs:WP_025710032	DNA topoisomerase III [Bacillus subtilis].	34.72	360	224	6	48	401	245	599	5e-60	220
sp:TOP3_BACCR	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	34.72	360	224	6	48	401	245	599	5e-60	220
rs:WP_011391892	DNA topoisomerase [Moorella thermoacetica].	33.97	418	250	8	36	446	137	535	5e-60	219
rs:WP_016231999	DNA topoisomerase III [Escherichia coli].	31.65	417	268	5	37	443	245	654	5e-60	220
rs:WP_016359326	DNA topoisomerase III [Pseudomonas fluorescens].	34.46	383	238	2	33	402	239	621	5e-60	220
rs:WP_000047294	DNA topoisomerase 3 [Bacillus cereus].	34.72	360	224	6	48	401	245	599	5e-60	220
rs:WP_023893457	DNA topoisomerase III [Salmonella enterica].	29.36	436	285	7	31	458	238	658	5e-60	220
rs:WP_036945020	DNA topoisomerase III [Pseudobacteroides cellulosolvens].	31.00	442	266	6	38	443	235	673	6e-60	219
rs:WP_012219851	DNA topoisomerase III [Vibrio sp. 23023].	29.76	494	277	5	31	459	241	729	6e-60	220
rs:WP_022584554	DNA topoisomerase III [Brevibacillus laterosporus].	36.57	350	213	5	47	391	245	590	6e-60	219
rs:WP_024139110	DNA topoisomerase III [Salmonella enterica].	29.59	436	284	7	31	458	238	658	6e-60	220
rs:WP_023155063	DNA topoisomerase [Escherichia coli].	32.84	408	257	5	37	432	245	647	6e-60	219
rs:WP_044790817	DNA topoisomerase III [Bacillus thuringiensis].	33.33	387	251	4	19	401	216	599	6e-60	219
rs:WP_012368885	DNA topoisomerase III [Proteus mirabilis].	32.82	454	264	11	27	459	239	672	6e-60	220
rs:WP_000047317	DNA topoisomerase III [Bacillus thuringiensis].	33.33	387	251	4	19	401	216	599	7e-60	219
rs:WP_000047292	DNA topoisomerase III [Bacillus cereus].	34.72	360	224	6	48	401	245	599	7e-60	219
rs:WP_000047316	DNA topoisomerase III [Bacillus cereus].	33.33	387	251	4	19	401	216	599	7e-60	219
rs:WP_036182463	DNA topoisomerase III [Lysinibacillus manganicus].	37.47	363	211	9	48	401	245	600	7e-60	219
rs:WP_015059543	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	32.84	408	257	5	37	432	245	647	7e-60	219
rs:WP_036218131	DNA topoisomerase III, partial [Lysinibacillus sphaericus].	36.24	356	218	5	47	397	243	594	7e-60	219
rs:WP_031620761	DNA topoisomerase III, partial [Salmonella enterica].	39.08	284	165	3	102	385	1	276	7e-60	209
rs:WP_001974718	DNA topoisomerase III [Bacillus cereus].	33.33	387	251	4	19	401	216	599	7e-60	219
rs:WP_019120897	DNA topoisomerase III [Brevibacillus massiliensis].	34.72	386	238	6	48	428	246	622	7e-60	219
rs:WP_039220949	DNA topoisomerase III [Clostridium novyi].	33.09	414	253	6	32	435	229	628	7e-60	219
rs:WP_039070763	DNA topoisomerase III [Brevibacillus borstelensis].	36.26	364	223	5	38	396	236	595	7e-60	219
rs:WP_006816384	DNA topoisomerase III [Providencia rustigianii].	32.60	454	265	11	27	459	239	672	8e-60	220
rs:WP_045852115	DNA topoisomerase III [Domibacillus enclensis].	37.72	342	199	7	69	401	263	599	8e-60	219
rs:WP_001235749	DNA topoisomerase III [Escherichia coli].	31.89	417	267	5	37	443	245	654	8e-60	219
rs:WP_036166771	DNA topoisomerase III, partial [Lysinibacillus sphaericus].	36.24	356	218	5	47	397	243	594	8e-60	219
rs:WP_027097876	DNA topoisomerase III [Clostridium paraputrificum].	33.85	387	233	5	46	425	242	612	8e-60	219
rs:WP_031932480	DNA topoisomerase III [Brevibacillus borstelensis].	36.26	364	223	5	38	396	236	595	8e-60	219
rs:WP_021528064	hypothetical protein [Escherichia coli].	31.89	417	267	5	37	443	245	654	8e-60	219
rs:WP_045635658	DNA topoisomerase III [Peptococcaceae bacterium BRH_c4a].	36.86	350	214	5	39	385	233	578	8e-60	219
rs:WP_023156604	DNA topoisomerase [Escherichia coli].	31.89	417	267	5	37	443	245	654	8e-60	219
rs:WP_046598252	DNA topoisomerase III [Salmonella enterica].	31.89	417	267	5	37	443	245	654	8e-60	219
rs:WP_006427725	DNA topoisomerase III [Dorea longicatena].	35.04	411	222	8	20	396	230	629	8e-60	219
rs:WP_031418403	DNA topoisomerase III [Lysinibacillus sphaericus].	36.24	356	218	5	47	397	243	594	9e-60	219
rs:WP_040037004	DNA topoisomerase III [Bacillaceae bacterium MTCC 10057].	36.66	341	203	4	48	385	245	575	9e-60	219
rs:WP_001140211	DNA topoisomerase III [Bacillus cereus].	33.51	388	249	5	19	401	216	599	9e-60	219
rs:WP_036162559	DNA topoisomerase III [Lysinibacillus sphaericus].	36.24	356	218	5	47	397	243	594	9e-60	219
tr:A0A090T775_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	40.07	272	156	2	36	307	106	370	9e-60	212
rs:WP_031623077	DNA topoisomerase III, partial [Salmonella enterica].	31.85	405	253	6	52	443	3	397	9e-60	214
rs:WP_039234965	DNA topoisomerase III [Bacillus thermotolerans].	36.66	341	203	4	48	385	245	575	9e-60	219
rs:WP_029364096	DNA topoisomerase III [Escherichia coli].	31.89	417	267	5	37	443	245	654	1e-59	219
rs:WP_023559145	DNA topoisomerase III [Brevibacillus panacihumi].	34.96	389	234	8	48	428	246	623	1e-59	219
tr:B1HZX0_LYSSC	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	36.24	356	218	5	47	397	246	597	1e-59	219
rs:WP_024535645	DNA topoisomerase III [Sporosarcina sp. EUR3 2.2.2].	36.86	350	197	6	59	398	257	592	1e-59	219
rs:WP_044795633	DNA topoisomerase III [Bacillus cereus].	34.44	360	225	6	48	401	245	599	1e-59	219
rs:WP_023171016	DNA topoisomerase III, partial [Salmonella enterica].	31.85	405	253	6	52	443	4	398	1e-59	214
rs:WP_000047319	DNA topoisomerase III [Bacillus thuringiensis].	35.10	359	224	5	48	401	245	599	1e-59	219
rs:WP_046199027	DNA topoisomerase III [Bacillus sp. UMTAT18].	33.33	387	251	4	19	401	216	599	1e-59	219
rs:WP_025399361	DNA topoisomerase III [Campylobacter coli].	33.18	446	268	11	32	458	233	667	1e-59	219
rs:WP_000047312	DNA topoisomerase III [Bacillus cereus].	33.33	387	251	4	19	401	216	599	1e-59	219
rs:WP_008176132	DNA topoisomerase III [Bacillus sp. B14905].	36.87	377	221	9	28	396	228	595	1e-59	219
rs:WP_002779644	MULTISPECIES: DNA topoisomerase III [Campylobacter].	33.18	446	268	11	32	458	233	667	1e-59	219
rs:WP_029268270	DNA topoisomerase III [Virgibacillus alimentarius].	32.87	362	231	4	40	396	237	591	1e-59	219
rs:WP_005540135	conjugal transfer protein TraE [Aggregatibacter actinomycetemcomitans].	30.86	431	272	7	36	458	247	659	1e-59	219
rs:WP_004444211	DNA topoisomerase III [Clostridium botulinum].	33.01	418	248	7	32	435	229	628	1e-59	219
rs:WP_033798013	DNA topoisomerase III [Bacillus mycoides].	33.33	417	263	7	25	435	221	628	1e-59	219
rs:WP_013625182	DNA topoisomerase III [Syntrophobotulus glycolicus].	33.91	404	254	5	36	435	233	627	1e-59	219
rs:WP_001235766	DNA topoisomerase III [Escherichia albertii].	31.97	416	267	4	37	443	245	653	1e-59	218
rs:WP_039259411	DNA topoisomerase III [Clostridium botulinum].	32.85	414	254	6	32	435	229	628	1e-59	219
rs:WP_040177565	DNA topoisomerase III, partial [Klebsiella pneumoniae].	33.17	416	248	8	60	459	18	419	1e-59	215
rs:WP_040235486	DNA topoisomerase III, partial [Klebsiella pneumoniae].	33.65	416	246	8	60	459	8	409	1e-59	214
gp:CP009679_388	DNA topoisomerase 3 [Bacillus methylotrophicus]	35.83	360	215	4	40	391	245	596	1e-59	219
rs:WP_038461743	MULTISPECIES: DNA topoisomerase III [Bacillus].	35.83	360	215	4	40	391	237	588	2e-59	218
rs:WP_044275906	hypothetical protein, partial [Burkholderia gladioli].	41.86	301	166	4	35	328	258	556	2e-59	215
rs:WP_036127568	MULTISPECIES: DNA topoisomerase III [Lysinibacillus].	35.96	356	219	5	47	397	243	594	2e-59	218
rs:WP_025983421	DNA topoisomerase III [Vibrio parahaemolyticus].	28.43	489	281	5	35	459	245	728	2e-59	218
rs:WP_044707261	DNA topoisomerase III [Escherichia coli].	32.45	416	265	4	37	443	245	653	2e-59	218
rs:WP_031515700	DNA topoisomerase III [Desulfotomaculum alkaliphilum].	33.84	393	247	5	40	428	237	620	2e-59	218
rs:WP_039257876	DNA topoisomerase III [Clostridium botulinum].	32.85	414	254	6	32	435	229	628	2e-59	218
rs:WP_028401311	DNA topoisomerase III [Bacillus panaciterrae].	35.36	362	224	6	40	396	237	593	2e-59	218
rs:WP_024614465	DNA topoisomerase III [Clostridium sp. Ade.TY].	36.86	350	203	6	36	377	232	571	2e-59	218
rs:WP_002383601	DNA topoisomerase III, partial [Yersinia pestis].	38.68	287	168	3	36	322	251	529	2e-59	214
rs:WP_022415164	DNA topoisomerase [Dorea longicatena CAG:42].	35.04	411	222	8	20	396	230	629	2e-59	219
rs:WP_023237100	DNA topoisomerase, partial [Salmonella enterica].	32.29	449	274	8	27	459	239	673	2e-59	218
rs:WP_039235853	DNA topoisomerase III [Clostridium sp. K25].	33.09	414	253	6	32	435	229	628	2e-59	218
rs:WP_042470619	DNA topoisomerase III [Bacillus sp. FF3].	36.49	370	223	7	35	397	231	595	2e-59	218
rs:WP_042840726	DNA topoisomerase III, partial [Salmonella enterica].	38.43	281	165	3	36	316	251	523	2e-59	214
rs:WP_039585037	DNA topoisomerase III, partial [Xanthomonas axonopodis].	37.95	332	193	6	51	375	1	326	2e-59	209
rs:WP_029437302	DNA topoisomerase III [Bacillus thuringiensis].	33.33	387	251	4	19	401	216	599	2e-59	218
rs:WP_036145479	DNA topoisomerase III [Lysinibacillus fusiformis].	35.96	356	219	5	47	397	243	594	2e-59	218
rs:WP_001235754	DNA topoisomerase III [Salmonella enterica].	31.65	417	268	5	37	443	245	654	2e-59	218
tr:V2NIF4_SALET	SubName: Full=Topoisomerase {ECO:0000313|EMBL:ESJ74434.1};	29.13	436	286	7	31	458	172	592	2e-59	218
rs:WP_039062795	DNA topoisomerase III [Bacillus amyloliquefaciens].	35.83	360	215	4	40	391	237	588	2e-59	218
rs:WP_000047313	DNA topoisomerase III [Bacillus thuringiensis].	33.07	387	252	4	19	401	216	599	2e-59	218
rs:WP_023225984	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	31.50	419	267	6	37	443	245	655	2e-59	218
rs:WP_015256841	MULTISPECIES: DNA topoisomerase III TopB [Enterobacteriaceae].	32.07	449	275	8	27	459	239	673	3e-59	218
rs:WP_022737202	DNA topoisomerase III [Laceyella sacchari].	34.96	409	251	7	32	435	230	628	3e-59	218
rs:WP_010274993	DNA topoisomerase III [Paenibacillus senegalensis].	34.97	429	241	11	25	445	222	620	3e-59	218
rs:WP_046424380	DNA topoisomerase III [Escherichia coli].	31.50	419	267	6	37	443	245	655	3e-59	218
rs:WP_043010875	DNA topoisomerase III [Campylobacter jejuni].	32.96	446	269	11	32	458	117	551	3e-59	216
rs:WP_025370374	hypothetical protein [Campylobacter fetus].	31.33	450	285	9	30	459	234	679	3e-59	218
rs:WP_042037109	DNA topoisomerase III, partial [Escherichia coli].	31.13	408	264	5	37	432	22	424	3e-59	213
tr:A0A0C7KFB3_XANCE	SubName: Full=TopB protein {ECO:0000313|EMBL:CEO96463.1};	37.78	360	208	8	38	387	239	592	3e-59	218
rs:WP_020061674	DNA topoisomerase III [Bacillus sp. 123MFChir2].	33.33	387	251	4	19	401	216	599	3e-59	218
rs:WP_046588404	DNA topoisomerase III [Bacillus sp. SA1-12].	36.64	363	218	7	48	403	244	601	3e-59	218
rs:WP_032119053	DNA topoisomerase III [Clostridium sp. CL-2].	34.71	363	223	5	36	391	232	587	3e-59	218
rs:WP_026680417	DNA topoisomerase III [Bacillus megaterium].	32.35	408	252	6	40	439	237	628	3e-59	218
rs:WP_046174720	DNA topoisomerase III [Domibacillus indicus].	36.86	350	207	5	48	394	244	582	3e-59	218
rs:WP_001129910	DNA topoisomerase III [Bacillus cereus].	33.59	387	250	4	19	401	216	599	3e-59	218
rs:WP_016221561	DNA topoisomerase III [Dorea sp. 5-2].	35.20	375	227	5	40	402	236	606	3e-59	218
rs:WP_025818807	DNA topoisomerase III [Vibrio parahaemolyticus].	28.43	489	281	6	35	459	245	728	3e-59	218
rs:WP_000765167	DNA topoisomerase III [Escherichia coli].	31.50	419	267	6	37	443	245	655	3e-59	218
rs:WP_001420449	DNA topoisomerase III family protein [Escherichia coli].	31.50	419	267	6	37	443	245	655	3e-59	218
tr:C2YLG1_BACCE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.59	387	250	4	19	401	220	603	3e-59	218
rs:WP_044704774	DNA topoisomerase III [Escherichia coli].	32.11	408	260	5	37	432	245	647	3e-59	218
rs:WP_015613674	DNA topoisomerase III [Clostridium pasteurianum].	35.15	367	228	6	36	396	232	594	3e-59	218
rs:WP_047674404	DNA topoisomerase III [Escherichia coli].	31.41	417	269	5	37	443	245	654	3e-59	217
rs:WP_013489388	DNA topoisomerase III [Bacillus cellulosilyticus].	33.84	393	243	6	50	435	248	630	4e-59	218
rs:WP_017366641	DNA topoisomerase III [Bacillus pumilus].	34.78	391	230	6	19	397	216	593	4e-59	217
rs:WP_024737330	DNA topoisomerase III [Clostridiales bacterium VE202-15].	35.05	408	243	10	32	428	230	626	4e-59	218
rs:WP_003230046	DNA topoisomerase III [Pseudomonas fluorescens].	31.97	416	256	3	1	404	222	622	4e-59	217
rs:WP_013843762	DNA topoisomerase III [Desulfotomaculum ruminis].	34.83	402	246	6	40	435	237	628	4e-59	217
rs:WP_015062761	MULTISPECIES: DNA topoisomerase III [Salmonella].	29.13	436	286	7	31	458	238	658	4e-59	218
rs:WP_034130836	DNA topoisomerase III [Peptococcaceae bacterium BICA1-8].	35.14	407	243	8	38	435	235	629	5e-59	217
rs:WP_045402153	DNA topoisomerase III [Vibrio campbellii].	28.43	489	281	6	35	459	245	728	5e-59	217
tr:L9TE08_SALEN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	39.08	284	165	3	102	385	1	276	5e-59	208
rs:WP_036659482	DNA topoisomerase III [Paenisporosarcina sp. HGH0030].	33.76	391	233	8	46	428	244	616	5e-59	217
rs:WP_036198354	DNA topoisomerase III [Lysinibacillus sinduriensis].	37.71	358	208	9	48	397	244	594	5e-59	217
rs:WP_002842888	DNA topoisomerase III [Campylobacter coli].	32.59	448	272	11	32	459	233	670	5e-59	216
rs:WP_046342695	DNA topoisomerase III [Bacillus pumilus].	34.78	391	230	6	19	397	216	593	5e-59	217
rs:WP_047946137	DNA topoisomerase III [Bacillus altitudinis].	34.78	391	230	6	19	397	216	593	5e-59	217
rs:WP_044825433	DNA topoisomerase III [Clostridium aceticum].	34.89	364	224	6	40	396	237	594	5e-59	217
gpu:CP008854_358	DNA topoisomerase III [Bacillus anthracis]	37.07	321	193	5	86	401	5	321	5e-59	211
rs:WP_025789708	DNA topoisomerase III [Vibrio parahaemolyticus].	28.43	489	281	6	35	459	245	728	6e-59	217
rs:WP_010532073	DNA topoisomerase III [Lentibacillus jeotgali].	31.86	408	249	7	37	435	234	621	6e-59	217
rs:WP_027094431	DNA topoisomerase III [Cohnella thermotolerans].	35.84	385	213	10	34	391	228	605	6e-59	218
rs:WP_041719022	DNA topoisomerase III [Alkaliphilus oremlandii].	33.42	389	231	7	49	425	246	618	6e-59	217
tr:M5RIR6_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	34.78	391	230	6	19	397	196	573	6e-59	216
rs:WP_013726277	DNA topoisomerase III [Clostridium botulinum].	33.58	399	241	6	47	435	244	628	6e-59	217
rs:WP_008347145	MULTISPECIES: DNA topoisomerase III [Bacillus].	34.78	391	230	6	19	397	216	593	6e-59	217
rs:WP_017382134	DNA topoisomerase III [Paenisporosarcina sp. TG-14].	34.13	378	223	8	59	428	257	616	6e-59	217
rs:WP_037319108	hypothetical protein, partial [Ruminobacter sp. RM87].	34.59	370	223	4	34	386	264	631	7e-59	215
tr:A8MG43_ALKOO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.42	389	231	7	49	425	257	629	7e-59	217
rs:WP_038888830	DNA topoisomerase III [Vibrio campbellii].	28.43	489	281	6	35	459	245	728	7e-59	217
rs:WP_002201907	DNA topoisomerase III [Bacillus cereus].	36.03	358	219	6	48	399	244	597	7e-59	217
rs:WP_018758435	hypothetical protein [Paenibacillus terrigena].	33.41	413	239	8	34	435	231	618	7e-59	216
tr:D8L9Y3_CAMFE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:CBH51817.1};	31.11	450	285	10	30	459	234	678	7e-59	217
tr:S2Y1I5_9BACL	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.76	391	233	8	46	428	290	662	8e-59	217
rs:WP_039963133	DNA topoisomerase III [Bacillus stratosphericus].	34.78	391	230	6	19	397	216	593	8e-59	216
rs:WP_046720418	DNA topoisomerase III [Pseudomonas syringae].	33.26	436	267	7	36	459	243	666	8e-59	216
rs:WP_034103981	DNA topoisomerase III [Desulfotomaculum sp. BICA1-6].	35.19	395	231	7	39	424	233	611	9e-59	216
rs:WP_010094284	DNA topoisomerase III [Ornithinibacillus scapharcae].	34.01	394	237	8	40	425	237	615	9e-59	216
rs:WP_047930289	DNA topoisomerase III [Clostridium botulinum].	33.58	399	241	6	47	435	244	628	1e-58	216
rs:WP_034122483	DNA topoisomerase III [Peptococcaceae bacterium BICA1-7].	36.41	390	234	8	40	425	234	613	1e-58	216
rs:WP_039980728	DNA topoisomerase III [Vibrio sagamiensis].	29.84	449	246	6	75	459	285	728	1e-58	216
rs:WP_010235392	DNA topoisomerase III [Clostridium arbusti].	35.36	362	225	6	40	396	237	594	1e-58	216
rs:WP_048311187	DNA topoisomerase III [Anaerobacillus macyae].	35.15	367	224	4	37	401	234	588	1e-58	216
rs:WP_003524410	DNA topoisomerase III [[Clostridium] clostridioforme].	36.89	366	215	8	48	402	244	604	1e-58	216
rs:WP_007860969	MULTISPECIES: DNA topoisomerase III [Clostridiales].	35.79	394	234	7	43	425	239	624	1e-58	216
rs:WP_035390408	DNA topoisomerase III [Bacillus sp. UNC125MFCrub1.1].	34.78	391	230	6	19	397	216	593	1e-58	216
rs:WP_022512351	DNA topoisomerase [Clostridium clostridioforme CAG:511].	36.89	366	215	8	48	402	244	604	1e-58	216
rs:WP_035703807	MULTISPECIES: DNA topoisomerase III [Bacillus].	35.04	391	229	6	19	397	216	593	1e-58	216
rs:WP_019554952	DNA topoisomerase III [Propionispira raffinosivorans].	33.57	429	250	11	35	449	244	651	1e-58	216
rs:WP_002593270	DNA topoisomerase III [[Clostridium] clostridioforme].	36.89	366	215	8	48	402	244	604	1e-58	216
rs:WP_002586183	DNA topoisomerase III [[Clostridium] clostridioforme].	36.89	366	215	8	48	402	244	604	1e-58	216
rs:WP_041091165	DNA topoisomerase III [Bacillus pumilus].	34.78	391	230	6	19	397	216	593	1e-58	216
rs:WP_019423519	DNA topoisomerase III [Paenibacillus sp. OSY-SE].	33.65	416	234	9	34	435	229	616	1e-58	216
rs:WP_028087322	DNA topoisomerase III [Dorea longicatena].	34.79	411	223	8	20	396	230	629	1e-58	216
rs:WP_038851175	DNA topoisomerase III, partial [Campylobacter coli].	32.96	446	269	11	32	458	233	667	1e-58	216
rs:WP_004614870	DNA topoisomerase III [Tyzzerella nexilis].	34.03	382	241	5	48	425	244	618	1e-58	216
rs:WP_032585756	DNA topoisomerase III [Campylobacter jejuni].	32.96	446	269	11	32	458	233	667	1e-58	216
rs:WP_036117504	DNA topoisomerase III [Lysinibacillus sphaericus].	36.44	376	224	8	28	396	228	595	2e-58	216
rs:WP_025206777	DNA topoisomerase III [Bacillus pumilus].	34.53	391	231	6	19	397	216	593	2e-58	216
rs:WP_044803320	DNA topoisomerase III, partial [Bacillus amyloliquefaciens].	37.08	356	210	7	74	425	2	347	2e-58	210
rs:WP_021657564	DNA topoisomerase [Clostridiales bacterium oral taxon 876].	33.58	408	243	8	40	435	237	628	2e-58	216
rs:WP_041019761	DNA topoisomerase III, partial [Xanthomonas axonopodis].	38.12	320	186	5	63	375	18	332	2e-58	207
rs:WP_021034341	hypothetical protein [Campylobacter coli].	32.96	446	269	11	32	458	233	667	2e-58	216
rs:WP_045492443	DNA topoisomerase III [Vibrio sp. 151112A].	28.22	489	282	6	35	459	245	728	2e-58	216
rs:WP_037349427	DNA topoisomerase III [Selenomonas artemidis].	33.02	421	255	10	36	445	243	647	2e-58	215
gp:CP002030_34	cpp49 [Campylobacter jejuni subsp. jejuni ICDCCJ07001]	32.74	446	270	11	32	458	233	667	2e-58	215
rs:WP_045243737	DNA topoisomerase III [Campylobacter coli].	32.96	446	269	11	32	458	233	667	2e-58	215
rs:WP_046059419	DNA topoisomerase III [Clostridium sp. IBUN22A].	35.06	348	216	3	46	391	242	581	2e-58	215
tr:F7S991_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.26	457	262	14	13	453	218	647	2e-58	215
rs:WP_011187245	DNA topoisomerase III [Campylobacter jejuni].	32.96	446	269	11	32	458	233	667	2e-58	215
rs:WP_032600155	DNA topoisomerase III, partial [Campylobacter jejuni].	32.74	446	270	11	32	458	233	667	2e-58	214
rs:WP_032587447	DNA topoisomerase III [Campylobacter jejuni].	32.96	446	269	11	32	458	233	667	2e-58	215
tr:A0A0F4VRR9_9CLOT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KJZ84248.1};	35.06	348	216	3	46	391	269	608	2e-58	216
rs:WP_019109223	MULTISPECIES: DNA topoisomerase III [Campylobacter].	32.96	446	269	11	32	458	233	667	2e-58	215
rs:WP_006036811	DNA topoisomerase III [Paenibacillus curdlanolyticus].	36.24	367	214	7	40	391	234	595	2e-58	216
rs:WP_048393340	DNA topoisomerase III [Lysinibacillus sp. LK3].	36.07	377	224	9	28	396	228	595	2e-58	215
rs:WP_001263213	DNA topoisomerase III [Vibrio sp. RC341].	27.61	489	285	5	35	459	245	728	2e-58	215
rs:WP_048238048	DNA topoisomerase III [Bacillus pumilus].	33.89	419	247	8	19	425	216	616	2e-58	215
rs:WP_044143441	hypothetical protein, partial [Succinimonas amylolytica].	35.23	369	212	7	36	377	246	614	2e-58	214
rs:WP_019555143	hypothetical protein [Propionispira raffinosivorans].	37.96	353	199	9	43	385	240	582	2e-58	215
rs:WP_024668910	DNA topoisomerase III, partial [Pseudomonas syringae].	35.29	357	214	3	33	375	240	593	3e-58	213
rs:WP_045282368	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	33.04	451	268	10	27	459	239	673	3e-58	215
rs:WP_005594981	DNA topoisomerase III, partial [Vibrio scophthalmi].	28.48	495	283	5	31	459	233	722	3e-58	215
rs:WP_002857817	DNA topoisomerase III [Campylobacter jejuni].	32.96	446	269	11	32	458	233	667	3e-58	215
rs:WP_036658025	DNA topoisomerase III [Paenibacillus larvae].	33.74	409	237	7	34	435	230	611	3e-58	214
rs:WP_032274624	DNA topoisomerase III [Escherichia coli].	31.26	419	268	6	37	443	245	655	3e-58	214
rs:WP_040068217	DNA topoisomerase III [Aeromonas veronii].	32.05	390	251	5	28	406	238	624	3e-58	214
tr:A0A078BQ75_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.24	428	267	6	35	459	239	646	4e-58	214
rs:WP_043012959	DNA topoisomerase III [Campylobacter jejuni].	32.74	446	270	11	32	458	233	667	4e-58	214
rs:WP_042106000	DNA topoisomerase III [Escherichia coli].	31.26	419	268	6	37	443	245	655	4e-58	214
rs:WP_048298780	DNA topoisomerase III [Klebsiella pneumoniae].	33.48	451	266	10	27	459	239	673	4e-58	215
rs:WP_045362785	DNA topoisomerase III [Enterobacter aerogenes].	33.48	451	266	10	27	459	239	673	4e-58	215
rs:WP_006717153	DNA topoisomerase III [Desulfitobacterium metallireducens].	34.83	402	243	5	40	435	236	624	4e-58	214
rs:WP_046790153	DNA topoisomerase III [Salinicoccus halodurans].	33.33	372	236	5	24	390	224	588	4e-58	214
rs:WP_017187990	DNA topoisomerase III [Vibrio harveyi].	29.32	440	283	5	35	459	245	671	4e-58	214
rs:WP_045325285	DNA topoisomerase III [Enterobacter cloacae].	33.48	451	266	10	27	459	239	673	4e-58	215
rs:WP_042968464	DNA topoisomerase III [Escherichia coli].	31.03	419	266	5	37	443	245	652	5e-58	214
rs:WP_007783982	DNA topoisomerase III [Brevibacillus sp. CF112].	34.87	390	235	8	47	428	245	623	5e-58	214
rs:WP_004225545	DNA topoisomerase III [Lysinibacillus fusiformis].	36.07	377	224	9	28	396	228	595	5e-58	214
rs:WP_047073258	DNA topoisomerase III [Brevibacillus formosus].	35.52	366	226	6	47	406	245	606	5e-58	214
rs:WP_019382435	DNA topoisomerase III [Bacillus oceanisediminis].	34.49	374	233	7	36	401	231	600	5e-58	214
rs:WP_047390804	DNA topoisomerase III [Carnobacterium sp. ZWU0011].	33.00	403	255	7	38	435	236	628	5e-58	214
rs:WP_033142648	DNA topoisomerase III [Blautia producta].	36.36	396	226	9	48	428	244	628	5e-58	214
rs:WP_038815648	DNA topoisomerase III [Campylobacter jejuni].	32.74	446	270	11	32	458	233	667	5e-58	214
rs:WP_006356165	DNA topoisomerase III [[Clostridium] methylpentosum].	32.85	414	250	8	28	435	227	618	6e-58	214
rs:WP_038834218	DNA topoisomerase III [Campylobacter coli].	32.74	446	270	11	32	458	233	667	6e-58	214
rs:WP_040647434	DNA topoisomerase III [Pseudoflavonifractor capillosus].	34.41	372	237	4	23	391	222	589	6e-58	214
rs:WP_025218532	DNA topoisomerase III [Lysinibacillus varians].	34.13	375	233	8	36	401	231	600	6e-58	214
rs:WP_044715191	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	32.67	450	269	10	27	458	239	672	6e-58	214
tr:M7NHP8_9BACT	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EMR01315.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EMR01315.1};	31.87	455	258	11	40	454	153	595	6e-58	213
rs:WP_048514467	DNA topoisomerase III [Megasphaera cerevisiae].	34.52	423	246	11	35	445	244	647	6e-58	214
tr:A6NZE3_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	34.41	372	237	4	23	391	225	592	7e-58	214
rs:WP_036962358	DNA topoisomerase III [Providencia alcalifaciens].	32.38	454	266	11	27	459	239	672	7e-58	214
rs:WP_043019247	DNA topoisomerase III, partial [Campylobacter jejuni].	32.51	446	271	11	32	458	233	667	7e-58	213
rs:WP_025435565	DNA topoisomerase III [Eubacterium acidaminophilum].	35.05	368	221	7	40	397	237	596	7e-58	214
rs:WP_046735973	DNA topoisomerase III, partial [Xanthomonas axonopodis].	38.12	320	186	5	63	375	66	380	7e-58	207
rs:WP_022250327	DNA topoisomerase [Clostridium nexile CAG:348].	33.51	382	243	5	48	425	244	618	8e-58	214
rs:WP_047680570	DNA topoisomerase III [Paenibacillus chondroitinus].	37.07	375	200	7	40	401	236	587	8e-58	214
rs:WP_032593162	DNA topoisomerase III [Campylobacter jejuni].	32.74	446	270	11	32	458	233	667	8e-58	214
tr:F8XQZ5_9GAMM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGQ62138.1}; Flags: Fragment;	39.94	318	172	8	143	459	4	303	8e-58	206
rs:WP_001689137	DNA topoisomerase, partial [Escherichia coli].	31.13	408	264	5	37	432	130	532	8e-58	212
rs:WP_041106477	DNA topoisomerase III [Bacillus pumilus].	34.25	400	233	8	38	425	235	616	9e-58	214
rs:WP_007708551	DNA topoisomerase III [[Clostridium] asparagiforme].	34.80	408	244	10	32	428	230	626	9e-58	214
rs:WP_046932116	DNA topoisomerase III [Xanthomonas gardneri].	38.06	360	207	7	38	387	239	592	9e-58	214
rs:WP_003225098	DNA topoisomerase III [Bacillus subtilis].	38.25	366	209	7	40	400	237	590	9e-58	214
rs:WP_042964849	DNA topoisomerase III [Campylobacter coli].	32.74	446	270	11	32	458	233	667	9e-58	214
rs:WP_025205685	DNA topoisomerase III [Dehalobacter restrictus].	36.49	348	216	4	40	385	234	578	9e-58	213
rs:WP_034664011	DNA topoisomerase III [Bacillus pumilus].	34.13	419	246	8	19	425	216	616	9e-58	213
rs:WP_045383398	DNA topoisomerase III [Bacillus subtilis].	38.25	366	209	7	40	400	237	590	9e-58	213
rs:WP_011187227	cpp49 [Campylobacter coli].	32.74	446	270	11	32	458	233	667	9e-58	213
rs:WP_014112696	DNA topoisomerase III [Bacillus subtilis].	38.52	366	208	7	40	400	237	590	9e-58	213
rs:WP_046831107	DNA topoisomerase III, partial [Xanthomonas axonopodis].	38.12	320	186	5	63	375	81	395	1e-57	207
rs:WP_026557999	DNA topoisomerase III [Bacillus sp. NSP2.1].	34.87	390	235	8	47	428	245	623	1e-57	213
rs:WP_040206221	MULTISPECIES: DNA topoisomerase III [Bacillus].	33.75	400	253	5	40	435	237	628	1e-57	213
rs:WP_019225406	DNA topoisomerase III [Dehalobacter sp. E1].	36.49	348	216	4	40	385	234	578	1e-57	213
rs:WP_027642235	DNA topoisomerase III [[Clostridium] clostridioforme].	35.99	389	231	9	48	428	244	622	1e-57	213
rs:WP_024427348	DNA topoisomerase III [Bacillus pumilus].	34.25	400	233	8	38	425	235	616	1e-57	213
rs:WP_042222299	DNA topoisomerase III [Oceanobacillus manasiensis].	32.40	392	246	6	40	425	237	615	1e-57	213
rs:WP_003440585	DNA topoisomerase III [Clostridium pasteurianum].	35.05	368	218	8	40	396	237	594	1e-57	213
rs:WP_021285572	DNA topoisomerase III [Clostridium sp. BL8].	31.69	426	258	9	20	435	226	628	1e-57	213
rs:WP_041116726	MULTISPECIES: DNA topoisomerase III [Bacillus].	34.25	400	233	8	38	425	235	616	1e-57	213
rs:WP_020492504	DNA topoisomerase III [Dehalobacter sp. FTH1].	36.49	348	216	4	40	385	234	578	1e-57	213
rs:WP_047081943	DNA topoisomerase III [Escherichia coli].	30.77	416	272	4	37	443	245	653	1e-57	213
rs:WP_045035034	DNA topoisomerase III [Bacillus invictae].	34.53	391	231	6	19	397	216	593	1e-57	213
rs:WP_045417592	DNA topoisomerase III [Vibrio owensii].	28.22	489	282	6	35	459	245	728	1e-57	213
rs:WP_011878189	DNA topoisomerase III [Desulfotomaculum reducens].	33.42	395	247	7	54	446	254	634	1e-57	213
rs:WP_034283847	DNA topoisomerase III [Bacillus safensis].	33.65	419	248	8	19	425	216	616	1e-57	213
rs:WP_039176652	DNA topoisomerase III [Bacillus sp. WP8].	34.25	400	233	8	38	425	235	616	1e-57	213
rs:WP_048001268	MULTISPECIES: DNA topoisomerase III [Bacillus].	34.20	386	239	5	19	397	216	593	1e-57	213
rs:WP_029392519	DNA topoisomerase III, partial [Escherichia coli].	31.13	408	264	5	37	432	171	573	1e-57	212
rs:WP_008357118	DNA topoisomerase III [Bacillus xiamenensis].	34.53	391	231	6	19	397	216	593	2e-57	213
rs:WP_024720230	DNA topoisomerase III [Bacillus pumilus].	34.53	391	231	6	19	397	216	593	2e-57	213
rs:WP_021977241	DNA topoisomerase [Ruminococcus sp. CAG:17].	34.40	375	232	4	60	428	256	622	2e-57	213
rs:WP_024425570	DNA topoisomerase III [Bacillus safensis].	33.41	419	249	8	19	425	216	616	2e-57	213
rs:WP_039873735	DNA topoisomerase III [Paenibacillus sp. FSL R7-0273].	36.59	369	212	7	40	391	234	597	2e-57	213
rs:WP_038816692	DNA topoisomerase III [Campylobacter jejuni].	32.51	446	271	11	32	458	233	667	2e-57	213
rs:WP_000765171	DNA topoisomerase III [Escherichia coli].	31.37	408	263	5	37	432	245	647	2e-57	213
rs:WP_044335056	DNA topoisomerase III [Bacillus safensis].	34.00	400	234	8	38	425	235	616	2e-57	213
rs:WP_024362789	DNA topoisomerase III [Lysinibacillus sphaericus].	34.13	375	233	8	36	401	231	600	2e-57	213
rs:WP_041904784	DNA topoisomerase III [Bacillus sp. BSC154].	38.25	366	209	7	40	400	237	590	2e-57	213
rs:WP_025093607	DNA topoisomerase III [Bacillus pumilus].	33.65	419	248	8	19	425	216	616	2e-57	213
rs:WP_016103242	DNA topoisomerase 3 [Bacillus cereus].	34.41	372	234	6	36	401	232	599	2e-57	213
rs:WP_018598357	DNA topoisomerase III [Blautia producta].	35.61	396	229	9	48	428	244	628	2e-57	213
rs:WP_045422785	DNA topoisomerase III [Vibrio jasicida].	27.76	490	283	6	35	459	245	728	2e-57	213
rs:WP_010857857	DNA topoisomerase III [Lysinibacillus sphaericus].	34.55	382	232	8	28	401	228	599	2e-57	213
rs:WP_041089158	DNA topoisomerase III [Bacillus pumilus].	34.25	400	233	8	38	425	235	616	2e-57	213
tr:A0A098EJ80_9BACL	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.71	425	249	10	12	428	217	612	2e-57	212
rs:WP_022030218	DNA topoisomerase [Clostridium hathewayi CAG:224].	36.88	385	229	6	51	428	252	629	2e-57	213
rs:WP_015893196	DNA topoisomerase III [Brevibacillus brevis].	35.25	366	227	6	47	406	245	606	2e-57	213
rs:WP_034622892	DNA topoisomerase III [Bacillus safensis].	34.88	387	222	8	51	425	248	616	2e-57	212
rs:WP_001235764	DNA topoisomerase III [Escherichia coli].	31.13	408	264	5	37	432	245	647	3e-57	212
tr:D4LXB5_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	35.14	370	222	6	68	428	261	621	3e-57	212
rs:WP_041508287	DNA topoisomerase III [Bacillus aerophilus].	34.95	372	217	6	38	397	235	593	3e-57	212
rs:WP_024026550	DNA topoisomerase III [Bacillus vireti].	34.25	400	251	5	40	435	237	628	3e-57	212
rs:WP_032249640	DNA topoisomerase III [Escherichia coli].	31.13	408	264	5	37	432	245	647	3e-57	212
rs:WP_028527329	DNA topoisomerase III [Ruminococcus gauvreauii].	34.93	375	232	5	60	428	256	624	3e-57	212
rs:WP_033544695	DNA topoisomerase III [Escherichia coli].	31.13	408	264	5	37	432	245	647	3e-57	212
rs:WP_010272697	DNA topoisomerase III [Paenibacillus senegalensis].	35.88	379	208	10	40	391	234	604	3e-57	213
rs:WP_035147711	DNA topoisomerase III [Clostridium tetanomorphum].	32.41	398	241	7	40	425	237	618	3e-57	212
rs:WP_038242886	DNA topoisomerase III [Virgibacillus sp. Vm-5].	33.09	405	253	6	40	439	237	628	3e-57	212
rs:WP_000765172	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	31.13	408	264	5	37	432	245	647	3e-57	212
rs:WP_001687633	DNA topoisomerase III family protein [Escherichia coli].	31.13	408	264	5	37	432	245	647	3e-57	212
tr:D2MXM3_CAMJU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EFC32963.1};	32.51	446	271	11	32	458	233	667	3e-57	213
rs:WP_039311041	DNA topoisomerase III, partial [Pectobacterium atrosepticum].	33.81	420	254	6	31	439	237	643	3e-57	212
rs:WP_034587670	DNA topoisomerase III [Helicobacter magdeburgensis].	31.97	441	273	8	35	459	240	669	3e-57	212
rs:WP_020314981	DNA topoisomerase III [Klebsiella pneumoniae].	31.13	408	264	5	37	432	245	647	3e-57	212
rs:WP_015057151	DNA topoisomerase III [Escherichia coli].	31.13	408	264	5	37	432	245	647	3e-57	212
rs:WP_006829182	DNA topoisomerase III [Planococcus antarcticus].	32.94	425	248	10	12	428	217	612	3e-57	212
rs:WP_040956109	DNA topoisomerase III [Virgibacillus sp. SK37].	33.52	364	234	4	40	401	237	594	3e-57	212
rs:WP_025380732	DNA topoisomerase III [Escherichia coli].	31.13	408	264	5	37	432	245	647	3e-57	212
rs:WP_000765166	DNA topoisomerase III [Escherichia coli].	31.13	408	264	5	37	432	245	647	3e-57	212
rs:WP_044317211	DNA topoisomerase III [Escherichia coli].	31.13	408	264	5	37	432	245	647	3e-57	212
rs:WP_021259547	DNA topoisomerase III [Paenibacillus alvei].	33.17	413	241	8	34	435	229	617	3e-57	212
tr:X3PRR7_SALEN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	37.83	267	158	3	36	302	6	264	3e-57	201
rs:WP_021503224	DNA topoisomerase III family protein [Escherichia coli].	31.13	408	264	5	37	432	245	647	3e-57	212
rs:WP_017415049	DNA topoisomerase III [Clostridium tunisiense].	31.69	426	258	9	20	435	226	628	3e-57	212
rs:WP_033560771	DNA topoisomerase III [Escherichia coli].	31.13	408	264	5	37	432	241	643	3e-57	212
rs:WP_047984422	DNA topoisomerase III [Ornithinibacillus californiensis].	35.18	361	224	4	40	396	237	591	4e-57	212
rs:WP_021538564	hypothetical protein [Escherichia coli].	31.13	408	264	5	37	432	245	647	4e-57	212
rs:WP_010302694	DNA topoisomerase III [Kurthia sp. JC8E].	34.51	368	232	5	36	397	231	595	4e-57	212
rs:WP_000765170	DNA topoisomerase III [Escherichia coli].	31.13	408	264	5	37	432	245	647	4e-57	212
rs:WP_047203830	DNA topoisomerase III [Bacillus pumilus].	34.00	400	234	8	38	425	235	616	4e-57	212
rs:WP_019414696	DNA topoisomerase III [Paenisporosarcina sp. TG20].	35.76	344	198	7	59	396	257	583	4e-57	212
rs:WP_029468332	DNA topoisomerase III [Clostridiales bacterium VE202-06].	35.61	396	229	9	48	428	244	628	4e-57	212
rs:WP_047972733	DNA topoisomerase III [Bacillus sp. LL01].	34.07	408	245	7	38	439	236	625	4e-57	212
tr:D4MPC5_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	35.56	419	238	6	9	406	217	624	4e-57	212
rs:WP_000765168	DNA topoisomerase III [Escherichia coli].	31.13	408	264	5	37	432	245	647	4e-57	211
rs:WP_015042714	MULTISPECIES: DNA topoisomerase III [Dehalobacter].	36.49	348	216	4	40	385	234	578	4e-57	211
rs:WP_021566151	hypothetical protein [Escherichia coli].	30.54	429	275	6	37	453	245	662	4e-57	211
rs:WP_019376018	DNA topoisomerase III [Virgibacillus halodenitrificans].	32.56	390	246	6	40	425	237	613	4e-57	211
rs:WP_002422089	DNA topoisomerase III, partial [Yersinia pestis].	37.94	282	167	3	36	317	251	524	4e-57	208
rs:WP_006783117	DNA topoisomerase III [Hungatella hathewayi].	36.21	359	223	4	32	385	230	587	5e-57	211
rs:WP_001542045	DNA topoisomerase III [Escherichia coli].	31.13	408	264	5	37	432	245	647	5e-57	211
rs:WP_008727758	DNA topoisomerase III [Erysipelotrichaceae bacterium 2_2_44A].	31.73	416	273	6	36	450	231	636	5e-57	211
rs:WP_016742873	DNA topoisomerase III [Brevibacillus brevis].	35.96	356	218	6	47	396	245	596	5e-57	211
rs:WP_044907297	DNA topoisomerase III [[Clostridium] innocuum].	31.97	416	272	6	36	450	231	636	5e-57	211
rs:WP_045657767	DNA topoisomerase III [Clostridiaceae bacterium BRH_c20a].	34.31	408	245	10	38	435	235	629	5e-57	211
rs:WP_007931300	MULTISPECIES: DNA topoisomerase III [Pelosinus].	33.99	356	228	4	40	391	238	590	5e-57	211
rs:WP_022066773	DNA topoisomerase III [Blautia sp. CAG:257].	35.52	366	227	3	47	406	243	605	5e-57	211
rs:WP_039542348	DNA topoisomerase III [Vibrio vulnificus].	27.40	489	286	5	35	459	245	728	5e-57	211
rs:WP_001547190	DNA topoisomerase III [Escherichia coli].	30.77	416	272	4	37	443	245	653	5e-57	211
tr:R5HVF0_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	36.86	369	216	6	69	428	262	622	5e-57	211
rs:WP_047828206	DNA topoisomerase III [Peptococcaceae bacterium CEB3].	36.15	390	237	8	39	425	233	613	6e-57	211
rs:WP_047741497	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	31.18	449	279	8	27	459	239	673	6e-57	212
rs:WP_038704788	DNA topoisomerase III [Planococcus sp. PAMC 21323].	34.18	392	230	8	12	397	217	586	6e-57	211
rs:WP_002609188	DNA topoisomerase III [[Clostridium] innocuum].	31.73	416	273	6	36	450	231	636	6e-57	211
rs:WP_006520575	DNA topoisomerase III [Desulfotomaculum gibsoniae].	34.01	397	242	8	54	446	253	633	6e-57	212
rs:WP_045575207	DNA topoisomerase III [Desulfosporosinus sp. I2].	36.80	375	205	10	40	392	255	619	7e-57	211
rs:WP_025983593	DNA topoisomerase III [Xanthomonas axonopodis].	38.44	359	205	7	39	387	240	592	7e-57	211
rs:WP_014827249	DNA topoisomerase III [Desulfosporosinus acidiphilus].	35.10	396	230	9	36	417	251	633	7e-57	211
rs:WP_010333072	DNA topoisomerase III [Bacillus mojavensis].	34.88	410	258	5	1	406	199	603	8e-57	211
rs:WP_002869583	DNA topoisomerase III [Campylobacter jejuni].	32.44	447	272	11	32	459	233	668	8e-57	210
rs:WP_006714456	DNA topoisomerase III [Vibrio ichthyoenteri].	29.49	495	277	10	31	459	235	723	8e-57	211
rs:WP_033543275	DNA topoisomerase III [Planococcus sp. CAU13].	33.93	392	231	8	12	397	217	586	9e-57	211
rs:WP_028548262	DNA topoisomerase III [Paenibacillus sp. UNC451MF].	34.31	408	234	8	38	435	234	617	9e-57	211
rs:WP_044161796	DNA topoisomerase III [Salinibacillus aidingensis].	34.63	410	259	5	1	406	199	603	9e-57	211
rs:WP_026478513	DNA topoisomerase III [Alkaliphilus transvaalensis].	34.44	360	229	4	38	393	235	591	9e-57	211
rs:WP_019257504	DNA topoisomerase III [Bacillus subtilis].	38.25	366	209	7	40	400	237	590	1e-56	211
rs:WP_034104804	DNA topoisomerase III [Desulfotomaculum sp. BICA1-6].	33.09	414	253	8	38	446	240	634	1e-56	211
rs:WP_044942795	DNA topoisomerase III [Flavonifractor plautii].	34.16	404	256	4	35	435	231	627	1e-56	211
tr:G9QKK7_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.30	418	250	7	19	428	224	616	1e-56	210
rs:WP_045643222	DNA topoisomerase III [Peptococcaceae bacterium BRH_c8a].	32.53	415	255	8	38	446	240	635	1e-56	211
tr:D4KE79_9FIRM	SubName: Full=Draft genome {ECO:0000313|EMBL:CBL06676.1};	38.19	288	159	4	181	459	2	279	1e-56	201
rs:WP_003240282	DNA topoisomerase III [Bacillus subtilis].	38.25	366	209	7	40	400	237	590	1e-56	210
rs:WP_025783241	DNA topoisomerase III [Sporosarcina sp. D27].	35.75	358	213	6	36	385	230	578	1e-56	210
rs:WP_019713359	DNA topoisomerase III [Bacillus subtilis].	37.98	366	210	7	40	400	237	590	1e-56	210
rs:WP_039971892	DNA topoisomerase III [Brevibacillus agri].	35.33	368	224	7	47	406	245	606	1e-56	210
rs:WP_017513937	hypothetical protein, partial [beta proteobacterium FWI2].	38.06	268	160	2	61	326	267	530	1e-56	207
rs:WP_008817173	DNA topoisomerase III [Peptoclostridium difficile].	31.73	416	273	6	36	450	231	636	1e-56	210
rs:WP_040341219	DNA topoisomerase III [Bacillus smithii].	32.30	418	250	7	19	428	227	619	1e-56	210
rs:WP_021563361	hypothetical protein [Escherichia coli].	30.88	408	265	5	37	432	245	647	1e-56	210
rs:WP_022300665	DNA topoisomerase [Erysipelotrichaceae bacterium CAG:64].	31.73	416	273	6	36	450	231	636	1e-56	210
rs:WP_006771625	DNA topoisomerase III [[Clostridium] hathewayi].	36.36	385	231	6	51	428	252	629	1e-56	210
tr:L5MM22_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	36.03	358	215	7	47	396	250	601	1e-56	210
tr:F0BTR5_9XANT	SubName: Full=Topoisomerase IA {ECO:0000313|EMBL:EGD13677.1}; Flags: Fragment;	38.89	360	204	8	38	387	239	592	1e-56	209
rs:WP_019162292	DNA topoisomerase III [Ruminococcus sp. JC304].	33.58	399	247	6	40	428	236	626	1e-56	210
rs:WP_013583068	DNA topoisomerase [Yersinia pestis].	32.68	407	260	4	36	432	243	645	1e-56	210
rs:WP_009587401	DNA topoisomerase III [Clostridium sp. HGF2].	31.73	416	273	6	36	450	231	636	1e-56	210
rs:WP_017251542	DNA topoisomerase III [Brevibacillus brevis].	34.70	366	229	6	47	406	245	606	2e-56	210
rs:WP_002589689	DNA topoisomerase III [[Clostridium] clostridioforme].	36.66	371	222	7	40	402	236	601	2e-56	210
rs:WP_010330854	DNA topoisomerase III [Bacillus vallismortis].	35.77	411	253	7	1	406	199	603	2e-56	210
rs:WP_001401704	DNA topoisomerase III family protein [Escherichia coli].	30.88	408	265	5	37	432	245	647	2e-56	210
rs:WP_022461978	DNA topoisomerase [Blautia sp. CAG:37].	34.83	356	227	3	40	391	236	590	2e-56	210
rs:WP_034898779	DNA topoisomerase III [Erwinia typographi].	30.63	395	252	5	31	406	245	636	2e-56	210
rs:WP_024120262	DNA topoisomerase III [Bacillus mojavensis].	34.63	410	259	5	1	406	199	603	2e-56	210
rs:WP_021966620	DNA topoisomerase [Clostridium sp. CAG:149].	35.32	419	239	6	9	406	217	624	2e-56	210
tr:A0A078BLX7_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.71	428	265	6	35	459	163	570	2e-56	209
rs:WP_001235768	DNA topoisomerase III [Escherichia coli].	31.97	416	267	4	37	443	245	653	2e-56	209
rs:WP_022272640	DNA topoisomerase [Clostridium sp. CAG:58].	34.61	393	237	6	48	428	244	628	2e-56	210
rs:WP_008396945	DNA topoisomerase III [Clostridium sp. M62/1].	36.08	388	226	4	40	406	238	624	2e-56	210
rs:WP_029197378	DNA topoisomerase III [Paenibacillus alginolyticus].	36.56	372	206	6	40	401	236	587	2e-56	209
rs:WP_004605342	DNA topoisomerase III [[Clostridium] scindens].	33.59	393	239	7	50	428	246	630	2e-56	209
rs:WP_043533225	DNA topoisomerase III [Klebsiella pneumoniae].	31.13	408	259	6	37	432	245	642	2e-56	209
rs:WP_044099716	DNA topoisomerase III [Xanthomonas citri].	39.17	360	203	8	38	387	239	592	2e-56	209
rs:WP_045642169	DNA topoisomerase III [Peptococcaceae bacterium BRH_c8a].	32.62	420	247	9	38	446	240	634	2e-56	210
rs:WP_011879513	DNA topoisomerase III [Desulfotomaculum reducens].	37.14	350	211	7	47	391	244	589	2e-56	209
rs:WP_007495750	DNA topoisomerase III [Flavonifractor plautii].	34.00	403	256	4	36	435	232	627	3e-56	209
rs:WP_021580495	hypothetical protein [Escherichia coli].	30.88	408	265	5	37	432	245	647	3e-56	209
rs:WP_033837181	MULTISPECIES: DNA topoisomerase III [Xanthomonas].	39.17	360	203	8	38	387	239	592	3e-56	209
rs:WP_036987227	DNA topoisomerase III, partial [Pseudomonas mendocina].	38.39	310	183	3	36	341	241	546	3e-56	206
rs:WP_015892060	DNA topoisomerase III [Brevibacillus brevis].	36.75	381	207	11	34	391	228	597	3e-56	209
rs:WP_012960832	DNA topoisomerase III [Bacillus pseudofirmus].	34.92	398	226	6	38	425	236	610	3e-56	209
rs:WP_002577786	DNA topoisomerase III [[Clostridium] bolteae].	36.66	371	222	7	40	402	236	601	3e-56	209
rs:WP_025848350	DNA topoisomerase III [Brevibacillus agri].	35.05	368	225	7	47	406	245	606	3e-56	209
rs:WP_048002376	DNA topoisomerase III [Bacillus stratosphericus].	34.27	391	232	6	19	397	216	593	3e-56	209
rs:WP_004841232	DNA topoisomerase III [[Ruminococcus] gnavus].	37.67	369	209	8	69	425	261	620	3e-56	209
rs:WP_021481725	DNA topoisomerase III [Bacillus sp. EGD-AK10].	36.29	372	227	6	40	406	237	603	3e-56	209
rs:WP_044702341	DNA topoisomerase III, partial [Escherichia coli].	38.24	272	160	3	36	307	251	514	3e-56	206
rs:WP_033166191	DNA topoisomerase III [Clostridium sp. KNHs205].	32.82	390	245	5	43	428	239	615	3e-56	209
rs:WP_009249709	DNA topoisomerase III [Lachnospiraceae bacterium 5_1_57FAA].	33.59	393	239	8	50	428	246	630	4e-56	209
rs:WP_023557382	DNA topoisomerase III [Brevibacillus panacihumi].	34.42	398	223	11	40	409	234	621	4e-56	209
rs:WP_032726499	DNA topoisomerase III [Bacillus subtilis].	36.29	372	227	6	40	406	237	603	4e-56	209
rs:WP_038827751	DNA topoisomerase III [Bacillus subtilis].	36.29	372	227	6	40	406	237	603	4e-56	209
rs:WP_019243290	DNA topoisomerase III [Bacillus massilioanorexius].	33.42	407	254	8	36	435	232	628	4e-56	209
rs:WP_040978776	DNA topoisomerase III [Oceanobacillus sp. S5].	34.79	365	226	6	36	396	233	589	4e-56	209
rs:WP_033575096	DNA topoisomerase III [Bacillus amyloliquefaciens].	35.28	360	217	4	40	391	237	588	4e-56	209
rs:WP_040154704	DNA topoisomerase III, partial [Klebsiella pneumoniae].	39.76	254	149	1	36	285	35	288	4e-56	199
rs:WP_009271940	DNA topoisomerase III [Erysipelotrichaceae bacterium 3_1_53].	32.61	417	268	7	36	450	231	636	4e-56	209
rs:WP_007955891	DNA topoisomerase III [Pelosinus fermentans].	33.99	356	228	4	40	391	238	590	4e-56	209
rs:WP_002602051	DNA topoisomerase III [Hungatella hathewayi].	36.62	385	230	7	51	428	252	629	4e-56	209
rs:WP_041351795	DNA topoisomerase III [Bacillus subtilis].	36.56	372	226	6	40	406	237	603	4e-56	209
rs:WP_048034684	DNA topoisomerase III [Brevibacillus brevis].	34.70	366	229	6	47	406	245	606	4e-56	209
rs:WP_041850711	DNA topoisomerase III [Bacillus subtilis].	36.29	372	227	6	40	406	237	603	4e-56	209
rs:WP_033118340	DNA topoisomerase III [Intestinimonas butyriciproducens].	32.74	394	259	2	36	428	232	620	4e-56	209
rs:WP_008496825	DNA topoisomerase III [Planococcus halocryophilus].	34.02	391	232	7	12	397	217	586	4e-56	209
rs:WP_009257548	DNA topoisomerase III [Lachnospiraceae bacterium 7_1_58FAA].	34.00	403	256	4	36	435	232	627	5e-56	209
rs:WP_014662817	DNA topoisomerase III [Bacillus sp. JS].	37.70	366	211	7	40	400	237	590	5e-56	209
rs:WP_029317313	MULTISPECIES: DNA topoisomerase 3 [Bacillus].	36.29	372	227	6	40	406	237	603	5e-56	209
sp:TOP3_BACSU	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	36.02	372	228	6	40	406	237	603	5e-56	209
rs:WP_002567851	DNA topoisomerase III [[Clostridium] bolteae].	36.66	371	222	7	40	402	236	601	5e-56	209
rs:WP_018674293	DNA topoisomerase III [Brevibacillus laterosporus].	35.43	350	217	5	47	391	245	590	5e-56	209
rs:WP_007728127	DNA topoisomerase III [Brevibacillus sp. BC25].	34.70	366	229	6	47	406	245	606	5e-56	209
rs:WP_014475847	DNA topoisomerase III [Bacillus subtilis].	36.29	372	227	6	40	406	237	603	5e-56	209
rs:WP_040227552	DNA topoisomerase III, partial [Bhargavaea cecembensis].	33.33	375	235	6	33	401	230	595	5e-56	207
rs:WP_003234388	DNA topoisomerase III [Bacillus subtilis].	36.29	372	227	6	40	406	237	603	5e-56	208
rs:WP_034288830	DNA topoisomerase III [Bacillus sp. 72].	33.76	394	239	7	48	435	244	621	6e-56	208
rs:WP_047970330	DNA topoisomerase III [Bacillus sp. LL01].	35.08	362	230	3	38	396	236	595	6e-56	208
rs:WP_047476276	DNA topoisomerase III [Bacillus amyloliquefaciens].	34.13	375	231	4	40	406	237	603	6e-56	208
gp:HF563562_395	DNA topoisomerase III [Bacillus amyloliquefaciens subsp. plantarum UCMB5036]	35.28	360	217	4	40	391	247	598	6e-56	209
rs:WP_015715259	DNA topoisomerase III [Bacillus subtilis].	36.29	372	227	6	40	406	237	603	6e-56	208
rs:WP_014478870	DNA topoisomerase III [Bacillus subtilis].	36.29	372	227	6	40	406	237	603	6e-56	208
rs:WP_029566545	DNA topoisomerase III [Bacillus cibi].	34.35	393	241	7	48	435	246	626	6e-56	208
rs:WP_028641865	hypothetical protein [Novosphingobium acidiphilum].	27.91	516	293	8	8	459	161	661	6e-56	207
rs:WP_039042718	DNA topoisomerase III [Sporosarcina sp. ZBG7A].	34.40	375	227	7	36	401	230	594	6e-56	208
rs:WP_039417357	DNA topoisomerase III [Xanthomonas euvesicatoria].	38.06	360	207	8	38	387	239	592	7e-56	208
rs:WP_015252793	DNA Topoisomerase III [Bacillus subtilis].	36.02	372	228	6	40	406	237	603	7e-56	208
rs:WP_008704037	DNA topoisomerase III [Ruminococcus sp. 5_1_39BFAA].	32.83	399	250	6	40	428	236	626	7e-56	208
rs:WP_040084142	DNA topoisomerase 3 [Bacillus sp. A053].	37.98	366	210	7	40	400	237	590	7e-56	208
rs:WP_024714484	DNA topoisomerase III [Bacillus tequilensis].	36.30	405	240	8	1	400	199	590	7e-56	208
rs:WP_028298222	DNA topoisomerase III [Olivibacter sitiensis].	33.18	428	240	14	47	449	240	646	7e-56	208
tr:D6DE15_CLOSC	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	35.00	420	240	6	9	406	217	625	7e-56	208
rs:WP_024573010	DNA topoisomerase III [Bacillus subtilis].	36.02	372	228	6	40	406	237	603	8e-56	208
rs:WP_016740752	DNA topoisomerase III [Brevibacillus brevis].	36.48	381	208	11	34	391	228	597	8e-56	208
rs:WP_036802988	DNA topoisomerase III [Planomicrobium glaciei].	31.53	425	254	9	12	428	217	612	8e-56	208
rs:WP_045926222	DNA topoisomerase III [Bacillus siamensis].	34.13	375	231	4	40	406	237	603	8e-56	208
rs:WP_025531347	DNA topoisomerase III [Hungatella hathewayi].	36.10	385	232	6	51	428	252	629	9e-56	208
rs:WP_039254980	DNA topoisomerase III [Bacillus sp. Pc3].	35.28	360	217	4	40	391	237	588	9e-56	208
rs:WP_041339607	DNA topoisomerase III [Bacillus subtilis].	36.29	372	227	6	40	406	237	603	1e-55	208
rs:WP_042977129	DNA topoisomerase III [Bacillus subtilis].	35.82	388	236	7	24	406	224	603	1e-55	208
rs:WP_031620292	DNA topoisomerase III, partial [Salmonella enterica].	33.71	350	219	3	37	377	245	590	1e-55	206
rs:WP_021254751	DNA topoisomerase III [Paenibacillus alvei].	33.17	413	241	9	34	435	229	617	1e-55	207
rs:WP_015239170	DNA topoisomerase III [Bacillus amyloliquefaciens].	35.28	360	217	4	40	391	237	588	1e-55	207
rs:WP_045509010	DNA topoisomerase III [Bacillus amyloliquefaciens].	35.28	360	217	4	40	391	237	588	1e-55	207
rs:WP_037986700	DNA topoisomerase III, partial [Tannerella sp. oral taxon BU063].	33.42	368	239	6	26	392	219	581	1e-55	206
rs:WP_045762245	DNA topoisomerase III [Xanthomonas albilineans].	37.78	360	209	7	38	387	239	593	1e-55	207
rs:WP_048033711	DNA topoisomerase III [Brevibacillus brevis].	35.79	380	212	10	34	391	228	597	1e-55	208
rs:WP_022629531	DNA topoisomerase III [Bacillus marmarensis].	35.18	398	225	6	38	425	236	610	1e-55	207
rs:WP_038460655	MULTISPECIES: DNA topoisomerase III [Bacillus subtilis group].	35.28	360	217	4	40	391	237	588	1e-55	207
rs:WP_029326219	MULTISPECIES: DNA topoisomerase III [Bacillus].	35.28	360	217	4	40	391	237	588	1e-55	207
rs:WP_035407321	DNA topoisomerase III [Bacillus sp. SJS].	35.08	362	221	6	34	391	232	583	1e-55	207
rs:WP_003156261	MULTISPECIES: DNA topoisomerase III [Bacillales].	35.28	360	217	4	40	391	237	588	1e-55	207
rs:WP_012116832	DNA topoisomerase III [Bacillus amyloliquefaciens].	35.28	360	217	4	40	391	237	588	1e-55	207
rs:WP_005997465	DNA topoisomerase III [Xanthomonas vesicatoria].	37.31	335	195	6	63	387	263	592	1e-55	207
rs:WP_038462366	MULTISPECIES: DNA topoisomerase III [Bacillus subtilis group].	35.28	360	217	4	40	391	237	588	1e-55	207
rs:WP_046932826	MULTISPECIES: DNA topoisomerase III [Xanthomonas].	37.31	335	195	6	63	387	263	592	1e-55	207
gp:CP006845_416	DNA topoisomerase III [Bacillus amyloliquefaciens CC178]	35.28	360	217	4	40	391	245	596	1e-55	207
rs:WP_043858106	DNA topoisomerase III [Bacillus subtilis].	36.02	372	228	6	40	406	237	603	1e-55	207
tr:S6FW61_BACAM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	35.28	360	217	4	40	391	247	598	1e-55	207
gp:HE774679_385	DNA topoisomerase III [Bacillus amyloliquefaciens subsp. plantarum YAU B9601-Y2]	35.28	360	217	4	40	391	245	596	1e-55	207
rs:WP_009245073	DNA topoisomerase III [Lachnospiraceae bacterium 2_1_58FAA].	37.13	369	211	8	69	425	261	620	1e-55	207
rs:WP_022038466	DNA topoisomerase [[Ruminococcus] gnavus].	37.13	369	211	8	69	425	261	620	1e-55	207
rs:WP_024084897	DNA topoisomerase III [Bacillus amyloliquefaciens].	35.28	360	217	4	40	391	237	588	1e-55	207
rs:WP_034630178	DNA topoisomerase III [Desulfotomaculum alcoholivorax].	33.65	419	254	10	38	450	237	637	1e-55	207
tr:I2HML6_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	35.28	360	217	4	40	391	247	598	2e-55	207
rs:WP_032870446	MULTISPECIES: DNA topoisomerase III [Bacillus].	35.28	360	217	4	40	391	237	588	2e-55	207
rs:WP_028532117	DNA topoisomerase III [Paenibacillus sp. UNC217MF].	33.17	413	241	9	34	435	229	617	2e-55	207
gp:CP006890_411	DNA topoisomerase III [Bacillus amyloliquefaciens SQR9]	35.28	360	217	4	40	391	247	598	2e-55	207
rs:WP_031378663	DNA topoisomerase III [Bacillus amyloliquefaciens].	35.00	360	218	4	40	391	237	588	2e-55	207
rs:WP_029575269	DNA topoisomerase III [Bacillus siamensis].	35.28	360	217	4	40	391	237	588	2e-55	207
tr:I2C1H1_BACAM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	35.28	360	217	4	40	391	247	598	2e-55	207
gp:CP007242_233	DNA topoisomerase III [Bacillus amyloliquefaciens subsp. amyloliquefaciens KHG19]	35.28	360	217	4	40	391	247	598	2e-55	207
rs:WP_007410181	DNA topoisomerase III [Bacillus sp. 916].	35.28	360	217	4	40	391	237	588	2e-55	207
rs:WP_017697341	DNA topoisomerase III [Bacillus subtilis].	36.02	372	228	6	40	406	237	603	2e-55	207
rs:WP_038427393	DNA topoisomerase 3 [Bacillus subtilis].	36.02	372	228	6	40	406	237	603	2e-55	207
gp:CP007165_390	DNA topoisomerase III [Bacillus amyloliquefaciens subsp. plantarum NJN6]	35.28	360	217	4	40	391	245	596	2e-55	207
rs:WP_042228689	DNA topoisomerase III [Paenibacillus chitinolyticus].	34.07	408	236	7	38	435	234	618	2e-55	207
rs:WP_009673239	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	34.07	408	236	7	38	435	234	618	2e-55	207
rs:WP_026092310	DNA topoisomerase III [Bacillus amyloliquefaciens].	35.28	360	217	4	40	391	237	588	2e-55	207
rs:WP_028555965	DNA topoisomerase III [Paenibacillus sp. URHA0014].	36.05	405	221	12	40	417	234	627	2e-55	207
rs:WP_025284251	DNA topoisomerase III [Bacillus amyloliquefaciens].	35.28	360	217	4	40	391	237	588	2e-55	207
rs:WP_026672191	DNA topoisomerase III [Bacillus bogoriensis].	34.09	399	224	8	54	435	252	628	2e-55	207
rs:WP_036590367	DNA topoisomerase III, partial [Paenibacillus sophorae].	35.31	388	204	10	40	396	234	605	2e-55	206
rs:WP_047936382	DNA topoisomerase III [Bacillus amyloliquefaciens].	35.28	360	217	4	40	391	237	588	2e-55	207
rs:WP_021289198	DNA topoisomerase III [Virgibacillus sp. CM-4].	32.59	405	255	6	40	439	237	628	2e-55	207
rs:WP_041336817	DNA topoisomerase III [Bacillus subtilis].	36.02	372	228	6	40	406	237	603	2e-55	207
rs:WP_034324734	DNA topoisomerase III [Bacillus sp. DW5-4].	33.65	419	248	8	19	425	216	616	2e-55	207
rs:WP_032866976	DNA topoisomerase III [Bacillus amyloliquefaciens].	35.28	360	217	4	40	391	237	588	2e-55	207
rs:WP_015382801	DNA topoisomerase III [Bacillus subtilis].	36.02	372	228	6	40	406	237	603	2e-55	207
rs:WP_010647795	DNA topoisomerase III [Oceanobacillus massiliensis].	33.06	366	230	5	37	396	234	590	2e-55	207
rs:WP_042678820	DNA topoisomerase III [Anaerosalibacter sp. ND1].	32.89	374	223	6	32	391	229	588	2e-55	207
gpu:CP011686_415	DNA topoisomerase III [Bacillus amyloliquefaciens]	35.28	360	217	4	40	391	247	598	3e-55	207
rs:WP_008430415	DNA topoisomerase III [Planococcus donghaensis].	33.76	391	233	7	12	397	217	586	3e-55	206
rs:WP_036723764	DNA topoisomerase III, partial [Paenibacillus forsythiae].	34.97	386	207	9	34	391	228	597	3e-55	205
rs:WP_034750165	DNA topoisomerase III [Bacillus wakoensis].	34.86	370	219	9	37	396	235	592	3e-55	206
rs:WP_038058568	hypothetical protein, partial [Thermodesulfovibrio islandicus].	33.51	370	224	9	26	391	245	596	3e-55	204
rs:WP_025335202	DNA topoisomerase III [Paenibacillus sabinae].	34.65	381	215	8	34	391	228	597	3e-55	207
rs:WP_002429351	DNA topoisomerase III, partial [Yersinia pestis].	37.63	279	166	3	36	314	251	521	3e-55	203
rs:WP_003490066	DNA topoisomerase III [Xanthomonas citri].	38.61	360	205	8	38	387	239	592	3e-55	206
rs:WP_041053511	DNA topoisomerase III [Jeotgalibacillus campisalis].	33.33	363	230	6	40	396	236	592	3e-55	206
rs:WP_007717774	DNA topoisomerase III [Brevibacillus sp. BC25].	35.79	380	212	10	34	391	228	597	4e-55	206
rs:WP_022446451	DNA topoisomerase III [Faecalibacterium sp. CAG:74].	34.86	370	226	5	34	392	232	597	4e-55	206
rs:WP_024633998	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	34.83	379	218	9	34	391	228	598	4e-55	206
rs:WP_022213677	DNA topoisomerase [Blautia sp. CAG:237].	32.73	388	247	4	47	428	243	622	4e-55	206
rs:WP_038484294	DNA topoisomerase III [Bacillus lehensis].	32.84	402	247	6	40	435	238	622	4e-55	206
rs:WP_021859574	DNA topoisomerase [Dorea sp. CAG:105].	33.08	396	233	8	51	428	262	643	4e-55	206
rs:WP_024853195	DNA topoisomerase III [[Ruminococcus] gnavus].	36.78	367	214	7	69	425	261	619	5e-55	206
rs:WP_033911109	conjugal transfer protein TraE, partial [Neisseria gonorrhoeae].	34.43	334	211	1	19	344	229	562	5e-55	203
rs:WP_046160064	DNA topoisomerase III [Bacillus sp. CMAA 1185].	36.02	372	228	6	40	406	237	603	5e-55	206
rs:WP_035070160	DNA topoisomerase III [Anditalea andensis].	33.10	432	252	14	47	459	240	653	5e-55	206
rs:WP_024292272	MULTISPECIES: DNA topoisomerase III [Lachnoclostridium].	36.36	374	225	6	59	428	258	622	5e-55	206
rs:WP_011066983	DNA topoisomerase III [Oceanobacillus iheyensis].	32.15	395	246	7	36	425	233	610	5e-55	206
rs:WP_010789663	IncP-type DNA topoisomerase III TraE [Bacillus atrophaeus].	35.68	370	229	5	38	402	235	600	5e-55	206
rs:WP_017797775	DNA topoisomerase III [Oceanobacillus kimchii].	32.41	395	243	7	37	425	234	610	6e-55	206
rs:WP_036851418	DNA topoisomerase III [Porphyromonas cangingivalis].	30.58	448	276	11	18	446	213	644	6e-55	205
rs:WP_009672854	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	34.15	410	233	10	29	411	223	622	6e-55	206
rs:WP_002597337	DNA topoisomerase III [Clostridium colicanis].	34.28	353	225	5	36	385	232	580	6e-55	206
rs:WP_042198563	DNA topoisomerase III [Paenibacillus sp. G4].	35.23	369	217	6	40	391	234	597	6e-55	206
rs:WP_022302692	DNA topoisomerase [Firmicutes bacterium CAG:227].	34.02	391	240	8	48	428	244	626	6e-55	206
rs:WP_042177283	DNA topoisomerase III [Paenibacillus sp. FSL R7-0331].	35.23	369	217	6	40	391	234	597	6e-55	206
rs:WP_006522960	DNA topoisomerase III [Desulfotomaculum gibsoniae].	33.98	359	225	6	40	391	237	590	6e-55	206
rs:WP_036078130	DNA topoisomerase III [Lysinibacillus boronitolerans].	35.90	376	226	8	28	396	228	595	6e-55	206
rs:WP_004430385	MULTISPECIES: DNA topoisomerase III [Bacillus subtilis group].	34.85	373	235	4	38	406	235	603	6e-55	206
rs:WP_008296568	DNA topoisomerase 3 [Bhargavaea cecembensis].	32.70	370	234	6	38	401	234	594	7e-55	205
rs:WP_047182112	DNA topoisomerase III [Bacillus subtilis].	35.75	372	229	6	40	406	237	603	7e-55	205
rs:WP_042206965	DNA topoisomerase III [Paenibacillus durus].	35.23	369	217	7	40	391	234	597	7e-55	206
rs:WP_035119416	DNA topoisomerase III [Cohnella panacarvi].	33.88	369	211	9	56	398	250	611	7e-55	206
tr:G4ADB6_AGGAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	38.37	258	152	2	50	307	1	251	7e-55	196
rs:WP_031304488	DNA topoisomerase III [Bacillus amyloliquefaciens].	34.72	360	219	4	40	391	237	588	8e-55	205
rs:WP_041937893	DNA topoisomerase III, partial [Klebsiella pneumoniae].	32.36	411	262	4	31	431	237	641	8e-55	205
rs:WP_013351049	MULTISPECIES: DNA topoisomerase III [Bacillus subtilis group].	34.72	360	219	4	40	391	237	588	8e-55	205
rs:WP_038592879	DNA topoisomerase III [Paenibacillus sp. FSL H7-0357].	34.38	416	246	9	40	435	234	642	9e-55	205
rs:WP_041481943	DNA topoisomerase III [Bacillus amyloliquefaciens].	35.00	360	218	4	40	391	237	588	9e-55	205
rs:WP_040636960	hypothetical protein, partial [Mucispirillum schaedleri].	28.38	437	286	7	35	458	244	666	1e-54	205
rs:WP_045761400	DNA topoisomerase III [Xanthomonas albilineans].	37.91	335	192	6	63	387	263	591	1e-54	205
rs:WP_003507970	DNA topoisomerase III [[Clostridium] symbiosum].	34.74	380	235	5	32	402	230	605	1e-54	205
rs:WP_014469759	DNA topoisomerase III [Bacillus amyloliquefaciens].	34.72	360	219	4	40	391	237	588	1e-54	205
rs:WP_024738311	DNA topoisomerase III [Clostridiales bacterium VE202-16].	34.74	380	235	5	32	402	230	605	1e-54	205
rs:WP_026909310	DNA topoisomerase III [Paucisalibacillus globulus].	31.75	400	250	7	35	425	230	615	1e-54	205
rs:WP_039476110	DNA topoisomerase III [Pectobacterium carotovorum].	32.16	454	269	11	28	459	240	676	1e-54	205
gp:HE617159_384	DNA topoisomerase III [Bacillus amyloliquefaciens subsp. plantarum CAU B946]	35.00	360	218	4	40	391	245	596	1e-54	205
rs:WP_003498632	MULTISPECIES: DNA topoisomerase III [Clostridiales].	34.74	380	235	5	32	402	230	605	1e-54	205
rs:WP_002667236	DNA topoisomerase III [Capnocytophaga gingivalis].	33.25	382	239	3	31	396	237	618	1e-54	205
rs:WP_008721172	DNA topoisomerase III [Clostridiales bacterium 1_7_47FAA].	33.00	403	255	6	43	439	239	632	1e-54	205
rs:WP_033193536	DNA topoisomerase III, partial [Amphibacillus jilinensis].	32.85	414	243	8	36	439	233	621	1e-54	204
rs:WP_006287544	topoisomerase IA [Paenibacillus popilliae].	33.49	415	246	7	38	447	233	622	1e-54	204
rs:WP_032595977	DNA topoisomerase III, partial [Campylobacter jejuni].	32.10	433	265	10	32	446	233	654	1e-54	204
tr:X4BAN5_SALEN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	37.83	267	158	3	36	302	251	509	1e-54	201
rs:WP_028557675	DNA topoisomerase III [Paenibacillus sp. URHA0014].	35.03	374	213	6	38	401	234	587	1e-54	204
rs:WP_021640469	DNA topoisomerase [[Clostridium] symbiosum].	34.74	380	235	5	32	402	230	605	1e-54	204
rs:WP_038563885	DNA topoisomerase III [Terribacillus aidingensis].	35.84	332	192	7	74	396	272	591	2e-54	204
rs:WP_020956887	DNA topoisomerase [Klebsiella pneumoniae].	32.36	411	262	4	31	431	237	641	2e-54	205
rs:WP_022035697	DNA topoisomerase III [Roseburia sp. CAG:50].	35.79	366	222	6	67	428	264	620	2e-54	204
tr:V2RK58_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ESJ98103.1};	28.38	437	286	7	35	458	244	666	2e-54	205
rs:WP_032212589	DNA topoisomerase III, partial [Escherichia coli].	37.88	264	156	3	36	299	164	419	2e-54	199
rs:WP_022201063	DNA topoisomerase [Clostridium clostridioforme CAG:132].	36.89	366	215	8	48	402	244	604	2e-54	204
tr:A0A095FRA6_BURML	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	35.65	432	240	13	40	459	240	645	2e-54	204
rs:WP_026893097	DNA topoisomerase III [[Clostridium] aerotolerans].	36.06	391	236	6	40	425	238	619	2e-54	204
rs:WP_021737651	DNA topoisomerase [Eubacterium ramulus].	35.52	366	223	6	67	428	264	620	2e-54	204
rs:WP_042233258	DNA topoisomerase III, partial [Paenibacillus chitinolyticus].	33.03	436	251	11	29	437	223	644	2e-54	203
rs:WP_024838128	DNA topoisomerase III [Clostridium sp. 12(A)].	36.06	391	236	6	40	425	238	619	2e-54	204
rs:WP_034125070	DNA topoisomerase III [Peptococcaceae bacterium BICA1-7].	32.31	424	258	12	36	446	238	645	2e-54	204
rs:WP_022426443	DNA topoisomerase [Ruminococcus sp. CAG:90].	34.31	376	232	5	60	428	256	623	2e-54	204
rs:WP_021632670	DNA topoisomerase, partial [Clostridium sp. ATCC BAA-442].	35.34	365	226	4	74	435	3	360	2e-54	199
rs:WP_041048759	DNA topoisomerase III [Paenibacillus sp. VKM B-2647].	35.09	379	220	6	34	391	228	601	3e-54	204
rs:WP_017249528	DNA topoisomerase III [Brevibacillus brevis].	35.56	374	209	10	40	391	234	597	3e-54	204
rs:WP_026648425	DNA topoisomerase III [Blautia wexlerae].	33.60	375	232	6	40	402	236	605	3e-54	204
rs:WP_014471442	DNA topoisomerase III [Bacillus amyloliquefaciens].	34.44	360	220	4	40	391	237	588	3e-54	204
rs:WP_039310023	DNA topoisomerase III [Clostridium botulinum].	31.99	397	251	6	36	425	232	616	3e-54	204
rs:WP_009247719	DNA topoisomerase III [Lachnospiraceae bacterium 6_1_63FAA].	33.93	389	234	7	48	428	244	617	3e-54	204
rs:WP_025483685	DNA topoisomerase III [Clostridiales bacterium VE202-28].	34.15	366	231	5	43	402	239	600	3e-54	204
rs:WP_027126573	DNA topoisomerase III [Gelidibacter mesophilus].	31.25	432	263	11	38	454	231	643	3e-54	204
rs:WP_047832168	DNA topoisomerase III [Robinsoniella sp. RHS].	33.85	390	245	6	17	402	220	600	3e-54	204
rs:WP_010197614	DNA topoisomerase III [Bacillus sp. m3-13].	33.98	362	234	3	38	396	236	595	3e-54	204
rs:WP_040287614	DNA topoisomerase III [Sporosarcina koreensis].	36.71	346	199	6	59	394	265	600	3e-54	204
rs:WP_043867614	DNA topoisomerase III [Bacillus amyloliquefaciens].	35.00	360	218	4	40	391	237	588	3e-54	204
tr:F3F3R3_PSEA0	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	37.78	315	179	5	36	336	244	555	3e-54	201
rs:WP_002937562	DNA topoisomerase III [Thauera sp. 27].	36.14	368	221	7	40	400	255	615	3e-54	204
rs:WP_042530086	DNA topoisomerase III [Oceanobacillus oncorhynchi].	34.69	369	219	6	37	396	234	589	3e-54	203
rs:WP_027414696	DNA topoisomerase III [Aneurinibacillus terranovensis].	33.43	350	213	3	38	385	234	565	3e-54	203
rs:WP_028059210	DNA topoisomerase III [Solirubrobacter sp. URHD0082].	31.10	418	271	7	37	449	246	651	3e-54	204
rs:WP_040942445	DNA topoisomerase III [Xanthomonas campestris].	34.92	358	218	6	63	410	250	602	4e-54	203
tr:W7ZP94_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	32.66	395	243	6	40	428	238	615	4e-54	203
rs:WP_044337321	DNA topoisomerase III [Bacillus aquimaris].	33.96	371	225	7	60	426	258	612	4e-54	203
tr:W4LTG6_9DELT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETX01011.1};	29.76	420	275	5	50	458	71	481	4e-54	201
rs:WP_040227468	hypothetical protein [Bhargavaea cecembensis].	34.21	342	211	5	65	401	2	334	4e-54	199
rs:WP_024344937	DNA topoisomerase III [[Clostridium] methoxybenzovorans].	36.63	374	224	6	59	428	258	622	4e-54	203
rs:WP_047810577	DNA topoisomerase III [Desulfosporosinus acididurans].	32.07	449	244	11	40	446	255	684	4e-54	203
rs:WP_044157940	DNA topoisomerase III [Salinibacillus aidingensis].	32.26	403	253	8	40	435	238	627	4e-54	203
rs:WP_019638659	DNA topoisomerase III [Paenibacillus fonticola].	34.69	369	216	10	40	391	234	594	4e-54	203
rs:WP_029194220	DNA topoisomerase III [Paenibacillus alginolyticus].	35.25	383	211	11	40	396	234	605	4e-54	203
rs:WP_027294681	DNA topoisomerase III [Robinsoniella sp. KNHs210].	33.85	390	245	6	17	402	220	600	5e-54	203
rs:WP_016408372	DNA topoisomerase III [Firmicutes bacterium CAG:102].	33.33	360	233	4	47	402	243	599	5e-54	203
tr:K4ZT14_PAEAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.37	414	245	9	34	435	236	626	5e-54	203
rs:WP_040735488	DNA topoisomerase III [Paenibacillus alvei].	32.37	414	245	9	34	435	229	619	5e-54	203
tr:A0A034TX81_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	38.71	248	145	1	32	279	2	242	5e-54	193
rs:WP_044053591	MULTISPECIES: DNA topoisomerase III [Bacillus].	35.18	361	217	5	40	391	237	589	5e-54	203
rs:WP_003019459	DNA topoisomerase III [Blautia hansenii].	33.92	395	230	8	42	428	246	617	5e-54	203
rs:WP_012008960	DNA topoisomerase III [Bacillus pumilus].	32.94	419	251	8	19	425	216	616	5e-54	203
rs:WP_022118737	DNA topoisomerase [Firmicutes bacterium CAG:56].	35.43	381	232	5	56	428	257	631	5e-54	203
rs:WP_026901741	DNA topoisomerase III [Peptostreptococcaceae bacterium VA2].	33.80	355	199	4	48	396	248	572	5e-54	202
rs:WP_005469461	DNA topoisomerase III [Porphyromonas catoniae].	33.81	420	253	13	38	446	237	642	5e-54	202
rs:WP_031649805	DNA topoisomerase III, partial [Listeria innocua].	33.51	385	237	5	18	399	10	378	5e-54	199
rs:WP_044297029	DNA topoisomerase III [Robinsoniella peoriensis].	33.85	390	245	6	17	402	220	600	6e-54	203
rs:WP_044423544	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	41.46	246	141	2	67	311	1	244	6e-54	192
rs:WP_014235929	DNA topoisomerase III [Azospira oryzae].	35.14	424	221	14	40	435	255	652	6e-54	204
rs:WP_002932995	DNA topoisomerase III [Thauera sp. 28].	36.14	368	221	7	40	400	255	615	6e-54	203
tr:A0A0D5V227_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.95	430	252	10	40	459	240	647	6e-54	204
rs:WP_047215475	DNA topoisomerase III [Pandoraea thiooxydans].	34.58	402	236	10	38	425	253	641	6e-54	203
rs:WP_025699539	DNA topoisomerase III, partial [Paenibacillus durus].	34.67	375	223	7	34	391	228	597	6e-54	202
rs:WP_036845770	DNA topoisomerase III [Porphyromonas cangingivalis].	30.80	448	275	11	18	446	213	644	7e-54	202
rs:WP_011563738	DNA topoisomerase III [Rubrobacter xylanophilus].	34.25	400	241	10	36	426	236	622	7e-54	202
rs:WP_042128274	DNA topoisomerase III [Paenibacillus sp. FSL R5-0345].	34.77	371	216	7	40	391	234	597	7e-54	203
rs:WP_045689151	DNA topoisomerase III [Hymenobacter sp. AT01-02].	32.00	450	259	13	30	446	246	681	7e-54	203
rs:WP_036156598	DNA topoisomerase III [Maribacter forsetii].	31.81	437	256	13	38	454	231	645	7e-54	203
rs:WP_021906870	DNA topoisomerase [Eubacterium sp. CAG:146].	34.96	369	218	7	66	428	261	613	7e-54	202
tr:W1HRD3_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	39.61	255	150	1	36	286	242	496	7e-54	199
rs:WP_042356994	DNA topoisomerase III [Bacillus sp. MT2].	35.11	356	220	6	48	397	245	595	7e-54	202
rs:WP_029283165	DNA topoisomerase III [Bacillus indicus].	33.93	392	242	7	49	435	247	626	7e-54	202
rs:WP_008688344	DNA topoisomerase III [Eubacterium sp. 3_1_31].	31.65	417	261	6	41	450	235	634	7e-54	202
rs:WP_032272977	DNA topoisomerase III, partial [Escherichia coli].	35.50	307	185	5	163	459	7	310	7e-54	196
rs:WP_015757378	DNA topoisomerase III [Desulfotomaculum acetoxidans].	31.31	444	278	8	9	446	264	686	8e-54	202
rs:WP_022400369	DNA topoisomerase [Roseburia sp. CAG:471].	35.08	362	219	7	74	428	270	622	8e-54	202
rs:WP_042630907	DNA topoisomerase III, partial [Escherichia coli].	32.63	380	232	6	94	459	1	370	8e-54	198
rs:WP_044423469	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	40.28	283	165	3	31	311	236	516	9e-54	199
rs:WP_031610507	DNA topoisomerase III, partial [Salmonella enterica].	32.30	356	224	5	98	443	4	352	9e-54	197
rs:WP_041073026	DNA topoisomerase III [Bacillus sp. OxB-1].	33.88	366	225	6	43	401	239	594	9e-54	202
rs:WP_045465464	DNA topoisomerase III [Burkholderiales bacterium GJ-E10].	33.17	413	242	11	54	459	257	642	9e-54	202
rs:WP_025788905	DNA topoisomerase III [Vibrio parahaemolyticus].	29.53	447	285	9	30	459	240	673	9e-54	202
rs:WP_047609382	DNA topoisomerase III, partial [Escherichia coli].	32.63	380	232	6	94	459	8	377	1e-53	198
rs:WP_022221047	DNA topoisomerase [Coprococcus comes CAG:19].	34.66	378	235	4	40	406	236	612	1e-53	202
rs:WP_028610693	DNA topoisomerase III [Paenibacillus harenae].	34.65	381	215	10	40	396	234	604	1e-53	202
rs:WP_011763832	DNA topoisomerase III [Azoarcus sp. BH72].	37.37	380	201	11	40	399	255	617	1e-53	202
rs:WP_008370080	DNA topoisomerase III [Coprococcus comes].	34.66	378	235	4	40	406	236	612	1e-53	202
rs:WP_047910610	DNA topoisomerase III [Paenibacillus sp. TCA20].	34.50	371	216	8	40	391	234	596	1e-53	202
rs:WP_022254546	DNA topoisomerase [Firmicutes bacterium CAG:466].	32.05	390	254	5	47	427	243	630	1e-53	202
rs:WP_025838455	DNA topoisomerase III [Porphyromonas cangingivalis].	30.58	448	276	11	18	446	213	644	2e-53	201
rs:WP_039299128	DNA topoisomerase III [Paenibacillus sp. IHB B 3415].	35.77	369	215	7	40	391	234	597	2e-53	202
rs:WP_046723272	DNA topoisomerase III [Paenibacillus durus].	34.67	375	223	7	34	391	228	597	2e-53	202
rs:WP_004302894	DNA topoisomerase III [Thauera aminoaromatica].	35.87	368	222	7	40	400	255	615	2e-53	202
rs:WP_036756511	hypothetical protein [Photobacterium halotolerans].	29.75	400	269	6	45	440	271	662	2e-53	202
rs:WP_012443232	DNA topoisomerase III [Erwinia tasmaniensis].	29.71	441	282	12	35	458	245	674	2e-53	201
rs:WP_021875939	DNA topoisomerase [Clostridium chauvoei].	30.77	403	253	6	36	428	232	618	2e-53	201
rs:WP_022387855	DNA topoisomerase [Ruminococcus obeum CAG:39].	35.43	350	207	6	69	406	262	604	2e-53	201
rs:WP_034145118	DNA topoisomerase III [Desulfosporosinus sp. BICA1-9].	35.48	372	214	10	40	392	255	619	2e-53	202
rs:WP_037994261	DNA topoisomerase III [Thermoactinomyces sp. Gus2-1].	34.00	403	245	8	38	435	231	617	2e-53	201
rs:WP_015042715	MULTISPECIES: DNA topoisomerase III [Dehalobacter].	34.22	377	222	8	40	393	255	628	2e-53	202
rs:WP_037497697	DNA topoisomerase III, partial [Solirubrobacter soli].	30.94	417	271	8	37	449	244	647	2e-53	201
rs:WP_047677729	DNA topoisomerase III [Paenibacillus chondroitinus].	35.25	383	211	11	40	396	234	605	2e-53	201
rs:WP_013271000	DNA topoisomerase III [[Clostridium] saccharolyticum].	36.36	374	225	6	59	428	258	622	2e-53	201
rs:WP_036687820	DNA topoisomerase III [Paenibacillus sp. FSL H8-237].	33.73	418	246	10	40	435	234	642	2e-53	201
tr:W4BTV7_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.73	418	246	10	40	435	236	644	2e-53	201
rs:WP_005307127	DNA topoisomerase III [Photobacterium damselae].	29.36	453	284	7	23	459	233	665	2e-53	201
rs:WP_022438027	DNA topoisomerase III [Prevotella sp. CAG:279].	32.72	437	265	14	27	446	220	644	2e-53	201
rs:WP_034633460	DNA topoisomerase III [Bacillus okhensis].	34.89	364	228	5	37	396	235	593	2e-53	201
rs:WP_010206361	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	40.81	272	157	3	31	300	32	301	3e-53	192
rs:WP_008978421	DNA topoisomerase III [Erysipelotrichaceae bacterium 5_2_54FAA].	30.99	426	252	7	41	450	235	634	3e-53	201
rs:WP_019225407	MULTISPECIES: DNA topoisomerase III [Dehalobacter].	34.22	377	222	8	40	393	255	628	3e-53	201
rs:WP_029497743	DNA topoisomerase III [Kurthia huakuii].	34.72	360	218	5	43	396	240	588	3e-53	201
rs:WP_043063478	DNA topoisomerase III [Aneurinibacillus migulanus].	32.30	418	241	9	32	438	228	614	3e-53	201
rs:WP_047068304	DNA topoisomerase III [Brevibacillus formosus].	35.26	380	214	10	34	391	228	597	3e-53	201
rs:WP_039836735	DNA topoisomerase III, partial [Paenibacillus sonchi].	34.51	368	220	6	40	391	234	596	3e-53	200
rs:WP_036892672	DNA topoisomerase III [Prevotella sp. S7-1-8].	30.91	440	269	11	24	438	217	646	3e-53	201
rs:WP_012584241	DNA topoisomerase III [Thauera sp. MZ1T].	35.87	368	222	7	40	400	255	615	3e-53	201
rs:WP_029706781	DNA topoisomerase III [Rhodoferax saidenbachensis].	35.89	365	215	7	47	399	269	626	3e-53	202
rs:WP_005426888	DNA topoisomerase III [[Ruminococcus] obeum].	35.14	350	208	6	69	406	262	604	3e-53	201
rs:WP_026475568	DNA topoisomerase III [Alkaliflexus imshenetskii].	30.67	450	278	13	18	452	212	642	3e-53	201
rs:WP_022364467	DNA topoisomerase [Clostridium sp. CAG:505].	32.05	390	254	5	47	427	243	630	3e-53	201
rs:WP_004257270	DNA topoisomerase III [Thauera sp. 63].	36.02	372	216	9	40	400	255	615	3e-53	201
rs:WP_038574535	DNA topoisomerase III [Paenibacillus odorifer].	33.57	414	244	10	40	431	234	638	4e-53	201
rs:WP_044140538	DNA topoisomerase III [Bacillus pumilus].	32.46	419	253	8	19	425	216	616	4e-53	201
rs:WP_040198136	DNA topoisomerase III [Candidatus Soleaferrea massiliensis].	32.68	358	229	5	41	396	237	584	4e-53	200
rs:WP_003214040	DNA topoisomerase III [Bacillus pumilus].	32.46	419	253	8	19	425	216	616	4e-53	201
rs:WP_026750054	DNA topoisomerase III [Listeria monocytogenes].	33.09	405	246	7	37	435	229	614	4e-53	200
rs:WP_025568346	DNA topoisomerase III [Bacillus sp. JGI 001005-J19].	34.38	384	237	6	19	396	216	590	4e-53	201
rs:WP_034667368	DNA topoisomerase III [Cellulophaga sp. E6(2014)].	32.79	433	257	13	38	454	231	645	4e-53	201
tr:D4LMY3_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	34.04	376	233	5	60	428	256	623	4e-53	201
rs:WP_036623080	DNA topoisomerase III [Paenibacillus macerans].	33.33	381	227	9	40	401	234	606	4e-53	201
rs:WP_021666915	DNA topoisomerase III [Porphyromonas sp. oral taxon 278].	32.38	420	261	10	38	446	237	644	4e-53	200
rs:WP_005344509	DNA topoisomerase III [[Eubacterium] hallii].	32.90	383	230	5	54	428	250	613	4e-53	200
rs:WP_017872293	hypothetical protein [Candidatus Caldatribacterium saccharofermentans].	32.83	396	243	7	40	426	239	620	4e-53	200
rs:WP_021652294	DNA topoisomerase [Blautia sp. KLE 1732].	34.04	376	233	5	60	428	256	623	4e-53	200
rs:WP_045131647	DNA topoisomerase III [Listeria monocytogenes].	32.52	409	243	7	37	435	229	614	4e-53	200
rs:WP_018716119	DNA topoisomerase III [Brachymonas chironomi].	34.65	355	216	7	40	385	262	609	4e-53	202
rs:WP_016562551	DNA topoisomerase III [Bacteroides sp. CAG:927].	34.72	360	226	7	39	397	232	583	4e-53	200
rs:WP_041729228	DNA topoisomerase III, partial [Desulfovibrio vulgaris].	36.34	344	203	5	47	385	288	620	4e-53	200
rs:WP_022169972	DNA topoisomerase [Eubacterium hallii CAG:12].	33.25	379	234	5	54	428	250	613	4e-53	200
rs:WP_035004309	DNA topoisomerase III, partial [Betaproteobacteria bacterium MOLA814].	33.89	422	242	12	18	421	247	649	4e-53	201
rs:WP_036575330	DNA topoisomerase III [Oceanobacillus picturae].	31.63	392	249	6	40	425	237	615	4e-53	200
rs:WP_026824282	DNA topoisomerase III, partial [Arsenophonus nasoniae].	32.92	407	259	6	36	432	171	573	5e-53	199
rs:WP_043070206	DNA topoisomerase III [Aneurinibacillus migulanus].	32.30	418	241	9	32	438	228	614	5e-53	200
rs:WP_010287202	DNA topoisomerase III [Kurthia massiliensis].	34.97	366	221	6	37	396	234	588	5e-53	200
tr:E3HYK0_ACHXA	SubName: Full=DNA topoisomerase III 3 {ECO:0000313|EMBL:ADP20154.1}; EC=5.99.1.2 {ECO:0000313|EMBL:ADP20154.1};	33.68	383	227	8	30	393	302	676	5e-53	200
rs:WP_046402305	MULTISPECIES: DNA topoisomerase III [Odoribacter].	30.09	452	273	11	18	446	212	643	5e-53	200
tr:V5AJ64_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.65	422	243	12	18	421	247	649	5e-53	201
rs:WP_035070810	DNA topoisomerase III, partial [Desulfovibrio termitidis].	36.89	347	199	6	44	385	290	621	5e-53	201
rs:WP_044786072	DNA topoisomerase III [Paenibacillus polymyxa].	33.65	422	248	11	40	438	234	646	5e-53	201
rs:WP_042096603	DNA topoisomerase III, partial [Escherichia coli].	32.15	367	229	6	89	443	10	368	5e-53	195
rs:WP_041657828	hypothetical protein [Achromobacter xylosoxidans].	33.68	383	227	8	30	393	289	663	5e-53	199
rs:WP_025365018	DNA topoisomerase III [Paenibacillus polymyxa].	33.65	422	248	11	40	438	234	646	5e-53	200
rs:WP_041918412	DNA topoisomerase III [Listeria innocua].	34.43	366	222	4	37	399	229	579	6e-53	200
rs:WP_022241545	DNA topoisomerase III [Clostridium sp. CAG:413].	34.78	345	214	2	53	391	249	588	6e-53	200
rs:WP_027066133	DNA topoisomerase III [Maribacter sp. Hel_I_7].	31.80	434	260	12	38	454	231	645	6e-53	200
rs:WP_025692666	DNA topoisomerase III [Paenibacillus zanthoxyli].	35.45	378	216	9	34	391	228	597	6e-53	200
rs:WP_029447957	DNA topoisomerase III [Cellulophaga baltica].	32.79	433	257	13	38	454	231	645	6e-53	200
rs:WP_013994551	DNA topoisomerase III [Zobellia galactanivorans].	31.80	434	260	12	38	454	231	645	7e-53	200
rs:WP_042188790	DNA topoisomerase III [Paenibacillus sp. FSL H7-0737].	34.50	371	217	7	40	391	234	597	7e-53	200
rs:WP_003728632	DNA topoisomerase III [Listeria monocytogenes].	34.69	369	217	6	37	399	229	579	7e-53	199
rs:WP_036705368	DNA topoisomerase III, partial [Paenibacillus graminis].	34.24	368	221	6	40	391	234	596	8e-53	199
rs:WP_041616898	DNA topoisomerase III [Paenibacillus mucilaginosus].	33.66	404	227	10	38	428	234	609	8e-53	199
tr:T0Y7L8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD31086.1}; Flags: Fragment;	32.79	366	226	7	46	407	3	352	8e-53	194
rs:WP_015058240	DNA topoisomerase III [Escherichia coli].	32.80	372	226	6	102	459	2	363	8e-53	195
rs:WP_038011289	DNA topoisomerase III, partial [Tannerella sp. oral taxon BU063].	33.16	374	235	8	26	392	219	584	8e-53	198
rs:WP_034598761	DNA topoisomerase III [Desulfosporosinus sp. HMP52].	32.61	463	246	13	36	446	251	699	8e-53	200
tr:W2C565_9PORP	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	33.16	374	235	8	26	392	219	584	9e-53	197
rs:WP_047546340	DNA topoisomerase III [Psychroserpens sp. Hel_I_66].	30.18	434	268	12	38	454	231	646	9e-53	200
rs:WP_027130404	DNA topoisomerase III [Gemella cuniculi].	32.63	380	232	8	73	451	263	619	9e-53	199
rs:WP_042236846	DNA topoisomerase III [Paenibacillus sp. FSL R5-0912].	35.50	369	216	7	40	391	234	597	9e-53	199
rs:WP_039276074	DNA topoisomerase III [Paenibacillus polymyxa].	33.41	422	249	11	40	438	234	646	9e-53	200
rs:WP_034327551	MULTISPECIES: DNA topoisomerase III [Helicobacter].	29.55	440	281	8	32	459	237	659	9e-53	199
tr:A0A078BQA6_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	35.85	357	202	9	40	385	262	602	1e-52	200
rs:WP_004381429	DNA topoisomerase III [Prevotella oulorum].	31.71	473	269	16	24	454	217	677	1e-52	199
rs:WP_024479295	DNA topoisomerase III [Cellulophaga baltica].	32.79	433	257	13	38	454	231	645	1e-52	199
rs:WP_043459152	hypothetical protein, partial [Azohydromonas australica].	32.41	435	262	11	40	459	133	550	1e-52	197
rs:WP_029445302	DNA topoisomerase III [Cellulophaga baltica].	32.79	433	257	13	38	454	231	645	1e-52	199
rs:WP_042797823	hypothetical protein [Achromobacter xylosoxidans].	32.90	383	230	7	30	393	289	663	1e-52	199
tr:F8F5Y2_PAEMK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.66	404	227	10	38	428	261	636	1e-52	199
tr:B8DNH0_DESVM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	37.46	347	195	6	47	385	288	620	1e-52	200
rs:WP_046504073	DNA topoisomerase III [Paenibacillus riograndensis].	34.51	368	220	6	40	391	234	596	1e-52	199
rs:WP_014370137	DNA topoisomerase III [Paenibacillus mucilaginosus].	33.66	404	227	10	38	428	234	609	1e-52	199
rs:WP_025613987	DNA topoisomerase III [Cellulophaga baltica].	32.79	433	257	13	38	454	231	645	1e-52	199
rs:WP_043741665	DNA topoisomerase III [Thauera sp. SWB20].	35.60	368	223	7	40	400	255	615	1e-52	200
rs:WP_036655982	DNA topoisomerase III [Paenibacillus wynnii].	34.42	369	220	7	40	391	234	597	1e-52	199
rs:WP_038283351	DNA topoisomerase III [[Clostridium] celerecrescens].	35.28	394	241	6	40	428	238	622	1e-52	199
rs:WP_013685590	DNA topoisomerase III [Fluviicola taffensis].	34.26	359	224	8	40	394	233	583	1e-52	199
rs:WP_013122335	DNA topoisomerase III [Thiomonas intermedia].	35.85	357	202	9	40	385	262	602	1e-52	199
rs:WP_014902554	DNA topoisomerase III [Desulfosporosinus meridiei].	32.68	459	247	13	36	446	251	695	1e-52	199
rs:WP_042266884	DNA topoisomerase III [Paenibacillus graminis].	34.24	368	221	6	40	391	234	596	1e-52	199
rs:WP_028403521	DNA topoisomerase III [Bacillus sp. J13].	32.92	401	234	12	40	414	234	625	1e-52	199
rs:WP_041617834	DNA topoisomerase III, partial [Paenibacillus mucilaginosus].	34.69	392	217	10	34	396	228	609	1e-52	198
rs:WP_038696442	DNA topoisomerase III [Paenibacillus stellifer].	34.41	372	216	9	40	391	234	597	2e-52	199
rs:WP_009461407	DNA topoisomerase III [Lachnospiraceae bacterium 2_1_46FAA].	35.45	347	202	5	66	402	262	596	2e-52	199
rs:WP_025950588	MULTISPECIES: DNA topoisomerase III [Geobacillus].	32.60	408	241	7	40	446	234	608	2e-52	198
rs:WP_006678765	DNA topoisomerase III [Paenibacillus dendritiformis].	32.63	426	256	8	38	458	233	632	2e-52	198
rs:WP_009226172	DNA topoisomerase III [Paenibacillus sp. oral taxon 786].	34.68	372	215	9	40	391	234	597	2e-52	199
rs:WP_035604100	DNA topoisomerase III [Hylemonella gracilis].	33.60	372	229	7	40	400	270	634	2e-52	200
tr:W2CXK5_9PORP	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	32.61	371	241	7	26	392	219	584	2e-52	197
rs:WP_021992003	DNA topoisomerase III [Prevotella sp. CAG:1092].	32.49	394	241	10	18	396	212	595	2e-52	198
rs:WP_029503852	DNA topoisomerase III [Lachnoclostridium phytofermentans].	30.91	385	249	5	48	428	244	615	2e-52	199
rs:WP_038709762	DNA topoisomerase III [Burkholderia sp. lig30].	36.31	358	202	8	38	385	253	594	2e-52	199
rs:WP_045640846	DNA topoisomerase III [Flavobacteriales bacterium BRH_c54].	31.26	451	274	13	18	454	212	640	2e-52	199
rs:WP_007130011	DNA topoisomerase III [Paenibacillus lactis].	32.92	401	234	12	40	414	234	625	2e-52	199
rs:WP_042147034	DNA topoisomerase III [Paucisalibacillus sp. EB02].	31.71	369	236	5	40	401	237	596	2e-52	198
rs:WP_014093960	DNA topoisomerase III [Listeria ivanovii].	34.70	366	221	5	37	399	229	579	2e-52	198
tr:U5N7W5_9BURK	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AGX87651.1};	34.67	375	224	7	40	401	287	653	2e-52	201
rs:WP_042137824	DNA topoisomerase III [Paenibacillus sp. FSL P4-0081].	34.15	369	221	6	40	391	234	597	2e-52	199
rs:WP_028537582	DNA topoisomerase III [Paenibacillus sp. J14].	34.03	382	224	9	40	401	234	607	2e-52	199
rs:WP_031461576	DNA topoisomerase III [Paenibacillus polymyxa].	33.41	422	249	11	40	438	234	646	2e-52	199
rs:WP_025670986	DNA topoisomerase III [Bacillus sp. JGI 001011-F15].	34.11	384	238	6	19	396	216	590	2e-52	198
rs:WP_022160958	DNA topoisomerase III [Odoribacter splanchnicus CAG:14].	29.98	457	271	12	18	446	212	647	2e-52	198
rs:WP_041193372	DNA topoisomerase III [Candidatus Symbiobacter mobilis].	34.67	375	224	7	40	401	282	648	2e-52	201
rs:WP_011586942	DNA topoisomerase III [Cytophaga hutchinsonii].	32.40	463	272	11	22	454	216	667	2e-52	198
rs:WP_014929276	DNA topoisomerase III [Listeria monocytogenes].	33.88	366	222	5	37	396	229	580	2e-52	198
gp:AE017262_2719	DNA topoisomerase III [Listeria monocytogenes serotype 4b str. F2365]	33.88	366	222	5	37	396	229	580	2e-52	198
rs:WP_029514379	DNA topoisomerase III [Paenibacillus polymyxa].	33.41	422	249	11	40	438	234	646	2e-52	199
rs:WP_042214434	DNA topoisomerase III [Paenibacillus borealis].	34.96	369	218	7	40	391	234	597	2e-52	199
rs:WP_014929862	DNA topoisomerase III [Listeria monocytogenes].	33.88	366	222	5	37	396	229	580	2e-52	198
rs:WP_012681475	DNA topoisomerase III [Listeria monocytogenes].	33.88	366	222	5	37	396	229	580	2e-52	198
rs:WP_017427723	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	33.41	422	249	11	40	438	234	646	2e-52	199
rs:WP_011791944	DNA topoisomerase III [Desulfovibrio vulgaris].	36.78	348	196	7	47	385	347	679	2e-52	199
rs:WP_011703393	DNA topoisomerase III [Listeria welshimeri].	33.79	367	219	5	39	399	231	579	2e-52	198
tr:D2U0X3_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	32.92	407	259	6	36	432	233	635	2e-52	198
rs:WP_023056591	MULTISPECIES: DNA topoisomerase III [Prevotella].	33.17	401	240	10	18	401	212	601	2e-52	197
rs:WP_003730738	DNA topoisomerase III [Listeria monocytogenes].	33.06	366	225	4	37	396	229	580	2e-52	198
tr:F7JP30_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.60	367	211	7	79	425	1	358	2e-52	194
rs:WP_026677990	DNA topoisomerase III [Fictibacillus gelatini].	32.11	408	230	7	36	434	230	599	2e-52	198
rs:WP_004361566	DNA topoisomerase III [Thauera phenylacetica].	35.33	368	224	7	40	400	255	615	2e-52	199
rs:WP_044879959	DNA topoisomerase III [Paenibacillus sp. IHBB 10380].	32.99	394	234	10	40	411	234	619	2e-52	198
rs:WP_034058450	DNA topoisomerase III [Lacinutrix sp. PAMC 27137].	30.74	462	269	14	18	454	212	647	2e-52	198
rs:WP_036695438	DNA topoisomerase III [Paenibacillus sp. FSL R7-269].	34.69	369	219	7	40	391	234	597	2e-52	198
rs:WP_003772809	DNA topoisomerase III [Listeria innocua].	34.15	366	223	4	37	399	229	579	3e-52	198
rs:WP_031644012	DNA topoisomerase III [Listeria monocytogenes].	34.42	369	218	6	37	399	229	579	3e-52	198
rs:WP_009917426	DNA topoisomerase III [Listeria monocytogenes].	33.88	366	222	5	37	396	229	580	3e-52	198
rs:WP_024721442	DNA topoisomerase III [Clostridiales bacterium VE202-01].	30.97	423	264	9	37	451	233	635	3e-52	198
rs:WP_010939590	DNA topoisomerase III [Desulfovibrio vulgaris].	36.78	348	196	7	47	385	347	679	3e-52	199
rs:WP_007651964	DNA topoisomerase III [Pontibacter sp. BAB1700].	32.42	438	255	13	37	443	230	657	3e-52	198
rs:WP_003727630	DNA topoisomerase III [Listeria monocytogenes].	34.42	369	218	6	37	399	229	579	3e-52	198
rs:WP_045244502	DNA topoisomerase III [Paenibacillus polymyxa].	33.41	422	249	11	40	438	234	646	3e-52	198
tr:W2CPA6_9PORP	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	33.15	368	240	6	26	392	219	581	3e-52	196
rs:WP_015846389	DNA topoisomerase III [Paenibacillus sp. JDR-2].	31.94	407	238	8	36	428	232	613	3e-52	198
rs:WP_033918257	DNA topoisomerase III [Listeria monocytogenes].	34.42	369	218	6	37	399	229	579	3e-52	198
rs:WP_033533770	DNA topoisomerase III [Listeria innocua].	34.15	366	223	4	37	399	229	579	3e-52	198
rs:WP_003725309	DNA topoisomerase III [Listeria monocytogenes].	34.42	369	218	6	37	399	229	579	3e-52	198
rs:WP_037982365	DNA topoisomerase III, partial [Tannerella sp. oral taxon BU063].	33.15	368	240	6	26	392	219	581	3e-52	196
rs:WP_031599127	DNA topoisomerase III [Ferrovum myxofaciens].	33.65	419	246	10	47	459	248	640	3e-52	197
rs:WP_028892471	DNA topoisomerase III [Tenacibaculum sp. 47A_GOM-205m].	31.03	435	265	11	38	454	231	648	3e-52	198
rs:WP_026815025	DNA topoisomerase III [Arenibacter certesii].	33.24	367	227	9	38	401	231	582	3e-52	198
rs:WP_016224225	DNA topoisomerase III [Lachnospiraceae bacterium 3-2].	32.35	408	230	7	54	428	250	644	3e-52	198
rs:WP_007649183	DNA topoisomerase III [Formosa sp. AK20].	32.79	369	231	8	38	401	231	587	3e-52	198
rs:WP_012582298	DNA topoisomerase III [Listeria monocytogenes].	34.42	369	218	6	37	399	229	579	3e-52	197
rs:WP_003739949	DNA topoisomerase III [Listeria monocytogenes].	34.42	369	218	6	37	399	229	579	3e-52	197
rs:WP_040249095	DNA topoisomerase III [Psychroserpens mesophilus].	30.48	433	270	12	38	454	231	648	3e-52	198
rs:WP_038408056	DNA topoisomerase III [Listeria ivanovii].	34.15	366	223	4	37	399	229	579	3e-52	197
rs:WP_025065874	DNA topoisomerase III [Prevotella enoeca].	33.76	394	241	11	18	402	212	594	3e-52	197
rs:WP_016362617	DNA topoisomerase III [Paenibacillus mucilaginosus].	34.69	392	217	10	34	396	228	609	3e-52	199
rs:WP_033010165	DNA topoisomerase III [Geobacillus stearothermophilus].	32.84	408	240	7	40	446	234	608	4e-52	197
rs:WP_033014155	DNA topoisomerase III [Geobacillus stearothermophilus].	32.11	408	243	6	40	446	234	608	4e-52	197
rs:WP_019004931	hypothetical protein [Cohnella laeviribosi].	32.79	433	242	11	34	425	228	652	4e-52	198
rs:WP_022010557	DNA topoisomerase [Firmicutes bacterium CAG:646].	35.82	335	206	5	48	377	48	378	4e-52	195
rs:WP_006318480	DNA topoisomerase III [Anoxybacillus flavithermus].	31.41	433	246	10	36	459	230	620	4e-52	197
rs:WP_023937515	DNA topoisomerase III [Porphyromonas crevioricanis].	34.12	422	261	11	37	449	230	643	4e-52	197
rs:WP_046724002	DNA topoisomerase III [Paenibacillus durus].	33.01	409	237	9	38	435	233	615	4e-52	197
rs:WP_023548258	DNA topoisomerase III [Listeria monocytogenes].	34.42	369	218	6	37	399	229	579	5e-52	197
rs:WP_028900129	DNA topoisomerase III [Prevotella sp. HJM029].	34.00	400	238	13	24	406	217	607	5e-52	197
rs:WP_044744310	DNA topoisomerase III [Anoxybacillus sp. ATCC BAA-2555].	32.84	408	240	7	40	446	234	608	5e-52	197
rs:WP_047790596	DNA topoisomerase III [Tenacibaculum mesophilum].	33.06	369	234	7	38	405	231	587	5e-52	197
rs:WP_023940994	DNA topoisomerase III [Porphyromonas crevioricanis].	34.12	422	261	11	37	449	230	643	5e-52	197
tr:A0A098ESY6_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.49	435	265	12	35	453	245	662	5e-52	197
rs:WP_022151843	DNA topoisomerase [Lachnospiraceae bacterium CAG:215].	35.77	355	201	7	69	400	264	614	5e-52	197
rs:WP_024992172	DNA topoisomerase III [Prevotella pleuritidis].	33.76	394	241	11	18	402	212	594	6e-52	197
rs:WP_044169014	DNA topoisomerase III [Porphyromonas catoniae].	32.20	441	271	13	18	446	218	642	6e-52	197
rs:WP_021583388	DNA topoisomerase III [Prevotella pleuritidis].	33.76	394	241	11	18	402	212	594	6e-52	197
rs:WP_011231183	DNA topoisomerase III [Geobacillus kaustophilus].	32.11	408	243	6	40	446	234	608	6e-52	197
rs:WP_032443669	DNA topoisomerase III, partial [Klebsiella pneumoniae].	32.02	356	225	5	89	432	10	360	6e-52	192
rs:WP_016312076	DNA topoisomerase III [Paenibacillus barengoltzii].	34.41	372	216	9	40	391	234	597	6e-52	197
rs:WP_025140922	hypothetical protein [Achromobacter sp. DH1f].	33.68	386	229	7	30	396	244	621	6e-52	196
rs:WP_047818361	DNA topoisomerase III [Geobacillus sp. 12AMOR1].	32.11	408	243	6	40	446	234	608	6e-52	197
rs:WP_022345006	DNA topoisomerase [Clostridium sp. CAG:299].	33.65	416	212	10	9	385	217	607	6e-52	197
rs:WP_032703532	DNA topoisomerase III, partial [Campylobacter coli].	32.02	406	248	9	41	428	1	396	6e-52	191
rs:WP_035933687	DNA topoisomerase III [Burkholderia glathei].	35.29	357	207	8	38	385	253	594	6e-52	198
rs:WP_039861625	DNA topoisomerase III [Lachnospiraceae bacterium 6_1_37FAA].	35.16	364	214	6	74	425	270	623	7e-52	197
rs:WP_013613151	DNA topoisomerase III [Odoribacter splanchnicus].	29.54	457	273	12	18	446	212	647	7e-52	197
rs:WP_004350923	DNA topoisomerase III [Prevotella buccalis].	33.17	401	240	10	18	401	212	601	8e-52	196
rs:WP_014194428	DNA topoisomerase [Burkholderia sp. YI23].	34.07	405	237	7	36	425	262	651	8e-52	197
rs:WP_013656949	DNA topoisomerase III [Cellulosilyticum lentocellum].	34.17	360	228	4	40	396	235	588	8e-52	197
rs:WP_044514344	DNA topoisomerase III [Hymenobacter sp. DG25B].	31.36	456	258	12	30	446	246	685	8e-52	197
rs:WP_020189016	DNA topoisomerase III [Kurthia sp. Dielmo].	33.87	375	227	6	59	428	257	615	8e-52	197
tr:E9RWM8_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	34.88	367	217	6	74	428	281	637	8e-52	197
rs:WP_029515045	DNA topoisomerase III [Paenibacillus polymyxa].	33.18	422	250	11	40	438	234	646	8e-52	197
rs:WP_031644988	DNA topoisomerase III [Listeria monocytogenes].	33.33	402	249	6	37	435	229	614	8e-52	196
rs:WP_046405598	DNA topoisomerase III [Odoribacter sp. N15.MGS-14].	29.98	457	271	12	18	446	212	647	9e-52	196
rs:WP_041086883	DNA topoisomerase III [Jeotgalibacillus soli Cunha et al. 2012].	33.52	364	233	6	40	398	237	596	9e-52	197
rs:WP_014219927	DNA topoisomerase III [Niastella koreensis].	32.56	430	248	11	47	449	240	654	9e-52	196
rs:WP_011876105	DNA topoisomerase [Burkholderia vietnamiensis].	33.83	405	238	7	36	425	262	651	9e-52	197
rs:WP_021853873	DNA topoisomerase III [Prevotella sp. CAG:255].	32.41	395	254	9	18	406	212	599	9e-52	196
rs:WP_018752813	DNA topoisomerase III [Paenibacillus sanguinis].	32.83	396	235	9	40	412	234	621	9e-52	197
rs:WP_027380549	DNA topoisomerase III [Chryseobacterium daeguense].	32.40	429	261	10	40	449	233	651	9e-52	196
rs:WP_023958691	DNA topoisomerase III [Paenibacillus sp. JCM 10914].	30.87	460	261	13	40	450	234	685	9e-52	197
rs:WP_008540190	DNA topoisomerase III [Megamonas funiformis].	30.52	426	258	13	35	449	241	639	9e-52	196
rs:WP_022372341	DNA topoisomerase [Sutterella sp. CAG:397].	33.02	424	240	14	40	449	254	647	1e-51	197
rs:WP_035810237	DNA topoisomerase III [Jeotgalicoccus sp. 13MG44_air].	32.51	403	237	7	43	435	238	615	1e-51	196
rs:WP_035968559	DNA topoisomerase III [Burkholderia grimmiae].	34.82	359	206	8	38	385	253	594	1e-51	197
rs:WP_044899422	DNA topoisomerase III [Aeribacillus pallidus].	32.86	426	255	11	36	446	244	653	1e-51	196
rs:WP_002804385	DNA topoisomerase III, partial [Campylobacter coli].	32.05	415	254	9	32	428	233	637	1e-51	195
rs:WP_043610175	DNA topoisomerase III, partial [Desulfovibrio sp. A2].	35.76	344	205	5	47	385	278	610	1e-51	196
rs:WP_028590838	DNA topoisomerase III [Paenibacillus panacisoli].	33.33	411	237	10	38	439	233	615	1e-51	196
rs:WP_017890391	hypothetical protein [Candidatus Caldatribacteirum californiense].	32.41	398	242	8	40	426	239	620	1e-51	196
rs:WP_047478073	DNA topoisomerase III [Chryseobacterium sp. CF356].	32.23	422	270	9	40	459	233	640	1e-51	196
rs:WP_008063202	DNA topoisomerase III [Methyloversatilis universalis].	35.18	398	232	11	40	425	255	638	1e-51	197
rs:WP_028396618	DNA topoisomerase III [Bacillus sp. FJAT-14578].	33.14	353	232	4	36	385	244	595	1e-51	196
rs:WP_027101633	DNA topoisomerase III [Comamonadaceae bacterium URHA0028].	33.15	365	222	7	47	400	282	635	1e-51	198
rs:WP_035295670	DNA topoisomerase III, partial [Brevibacillus thermoruber].	32.86	426	255	12	36	446	244	653	1e-51	196
rs:WP_006675493	DNA topoisomerase III [Paenibacillus dendritiformis].	34.20	386	223	10	34	396	228	605	1e-51	196
rs:WP_038409316	DNA topoisomerase III [Listeria ivanovii].	34.15	366	223	4	37	399	229	579	1e-51	196
rs:WP_039438134	DNA topoisomerase III [Porphyromonas gulae].	35.26	380	230	10	17	392	211	578	1e-51	196
rs:WP_018227575	DNA topoisomerase III [Methyloversatilis universalis].	35.34	399	230	12	40	425	255	638	1e-51	197
rs:WP_009548295	DNA topoisomerase III [Burkholderiales bacterium JOSHI_001].	34.62	416	240	10	40	439	263	662	1e-51	197
rs:WP_042626312	DNA topoisomerase III [Burkholderia glumae].	35.75	358	204	8	38	385	253	594	1e-51	197
rs:WP_018885393	DNA topoisomerase III [Paenibacillus massiliensis].	34.63	410	233	10	38	439	233	615	1e-51	196
rs:WP_016441614	DNA topoisomerase III [Coprococcus sp. HPP0048].	35.16	364	214	6	74	425	270	623	1e-51	196
rs:WP_003740322	DNA topoisomerase III [Listeria monocytogenes].	34.15	369	219	6	37	399	229	579	1e-51	196
rs:WP_022381016	DNA topoisomerase [Ruminococcus sp. CAG:9].	32.17	401	250	6	40	428	236	626	1e-51	196
rs:WP_021851957	DNA topoisomerase III [Prevotella sp. CAG:1058].	32.91	392	245	10	24	406	217	599	1e-51	196
rs:WP_025580044	DNA topoisomerase III [Blautia wexlerae].	32.17	401	250	6	40	428	236	626	2e-51	196
rs:WP_004033898	DNA topoisomerase III [Clostridium sp. ASF356].	31.23	349	232	3	47	392	244	587	2e-51	196
rs:WP_045785422	DNA topoisomerase III [Ralstonia mannitolilytica].	34.74	403	225	13	38	425	253	632	2e-51	196
rs:WP_046324898	DNA topoisomerase III [Listeria seeligeri].	32.50	400	251	5	39	435	231	614	2e-51	196
tr:A0A0B6S0Y1_BURGL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	35.75	358	204	8	38	385	275	616	2e-51	197
rs:WP_046200217	DNA topoisomerase III [Porphyromonas gulae].	33.56	450	262	15	17	446	211	643	2e-51	195
rs:WP_016439735	DNA topoisomerase III [Coprococcus sp. HPP0074].	35.16	364	214	6	74	425	270	623	2e-51	196
rs:WP_009263044	DNA topoisomerase III [Lachnospiraceae bacterium 9_1_43BFAA].	35.16	364	214	6	74	425	270	623	2e-51	196
rs:WP_040281935	DNA topoisomerase III [Psychroserpens damuponensis].	30.75	426	263	11	38	448	231	639	2e-51	196
rs:WP_031236772	DNA topoisomerase III, partial [Salmonella enterica].	29.37	378	257	3	31	400	197	572	2e-51	194
rs:WP_036872645	DNA topoisomerase III [Prevotella buccalis].	32.92	401	241	10	18	401	212	601	2e-51	194
rs:WP_034611031	DNA topoisomerase III [Desulfosporosinus sp. Tol-M].	33.97	418	246	11	40	438	255	661	2e-51	196
rs:WP_016778794	DNA topoisomerase III [Anaerophaga thermohalophila].	31.01	445	279	12	27	454	220	653	2e-51	196
rs:WP_026752833	DNA topoisomerase III [Sediminibacter sp. Hel_I_10].	30.50	436	264	13	38	454	231	646	2e-51	196
rs:WP_026630256	DNA topoisomerase III [Dyadobacter alkalitolerans].	32.54	421	242	13	61	454	254	659	2e-51	196
rs:WP_013104829	DNA topoisomerase III [Thiomonas arsenitoxydans].	35.29	357	204	9	40	385	262	602	2e-51	196
tr:G2HD77_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	35.76	344	205	5	47	385	278	610	2e-51	196
rs:WP_045853554	DNA topoisomerase III [Raoultella terrigena].	31.87	411	261	6	31	428	240	644	2e-51	196
rs:WP_028121874	DNA topoisomerase III [Epilithonimonas tenax].	33.02	430	262	10	40	454	233	651	2e-51	195
rs:WP_036928229	DNA topoisomerase III [Prevotella timonensis].	32.58	396	249	9	18	401	212	601	2e-51	194
rs:WP_029099989	DNA topoisomerase III [Brevibacillus thermoruber].	32.86	426	255	12	36	446	244	653	2e-51	196
rs:WP_003732116	DNA topoisomerase III [Listeria monocytogenes].	34.70	366	221	5	37	399	229	579	2e-51	195
rs:WP_033920949	DNA topoisomerase III [Listeria monocytogenes].	34.70	366	221	5	37	399	229	579	2e-51	195
rs:WP_020959817	DNA topoisomerase III [Geobacillus sp. JF8].	30.96	407	248	4	40	446	234	607	2e-51	195
rs:WP_021326569	DNA topoisomerase III, partial [Photorhabdus temperata].	42.86	217	124	0	36	252	242	458	2e-51	191
rs:WP_039427007	DNA topoisomerase III [Porphyromonas gulae].	33.56	450	262	15	17	446	211	643	2e-51	195
rs:WP_042299241	DNA topoisomerase III [Burkholderia kururiensis].	36.03	358	203	8	38	385	253	594	2e-51	196
rs:WP_015267562	DNA topoisomerase III [Echinicola vietnamensis].	31.78	387	249	9	18	399	212	588	2e-51	196
rs:WP_040058895	hypothetical protein [Bacillus sp. REN51N].	29.80	396	252	7	50	426	255	643	2e-51	196
rs:WP_028548283	DNA topoisomerase III [Paenibacillus sp. UNC451MF].	34.39	378	220	9	34	391	228	597	2e-51	196
rs:WP_040427933	DNA topoisomerase III, partial [Acetivibrio cellulolyticus].	32.79	366	230	7	38	399	236	589	2e-51	194
tr:W7Z0Q0_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.73	394	250	6	40	428	238	617	3e-51	195
rs:WP_036726462	DNA topoisomerase III [Paenibacillus sp. FSL R7-277].	33.17	410	240	9	40	420	234	638	3e-51	195
rs:WP_021620860	DNA topoisomerase [Aneurinibacillus aneurinilyticus].	31.45	407	243	8	40	438	236	614	3e-51	195
rs:WP_010136018	DNA topoisomerase III [Flavobacteriaceae bacterium S85].	29.82	446	278	13	18	446	212	639	3e-51	195
rs:WP_047421433	DNA topoisomerase III [Chryseobacterium sp. YR480].	32.25	431	260	11	40	449	233	652	3e-51	195
rs:WP_025761771	DNA topoisomerase III [Dyadobacter tibetensis].	31.09	431	267	10	40	454	233	649	3e-51	195
rs:WP_012986588	DNA topoisomerase III [Listeria seeligeri].	32.25	400	252	5	39	435	231	614	3e-51	195
tr:C0FRI7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	32.03	434	248	13	47	446	263	683	3e-51	196
rs:WP_008125946	DNA topoisomerase III [Prevotella timonensis].	32.58	396	249	9	18	401	212	601	3e-51	194
rs:WP_045121307	hypothetical protein, partial [Haliangium ochraceum].	33.06	363	222	6	47	400	288	638	3e-51	196
rs:WP_028979020	DNA topoisomerase III [Sporocytophaga myxococcoides].	33.88	363	229	8	47	407	240	593	3e-51	196
rs:WP_004278181	DNA topoisomerase III [Campylobacter upsaliensis].	30.40	454	239	9	62	450	266	707	3e-51	195
rs:WP_027384776	DNA topoisomerase III [Chryseobacterium caeni].	32.74	446	265	11	28	449	211	645	3e-51	195
rs:WP_020325450	hypothetical protein, partial [Pseudomonas syringae].	34.76	328	197	3	33	346	240	564	3e-51	193
rs:WP_019910740	DNA topoisomerase III [Paenibacillus sp. HW567].	34.42	369	220	7	40	391	234	597	3e-51	195
rs:WP_038493688	DNA topoisomerase III [Collimonas arenae].	33.00	397	242	9	40	426	255	637	3e-51	196
rs:WP_038673289	DNA topoisomerase III [Pelosinus sp. UFO1].	32.58	356	233	4	40	391	238	590	3e-51	195
rs:WP_039446752	DNA topoisomerase III [Porphyromonas gulae].	35.00	380	231	10	17	392	211	578	3e-51	194
tr:A0A0C7EU68_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.10	412	239	7	20	425	226	594	3e-51	195
rs:WP_036890366	DNA topoisomerase III [Porphyromonas crevioricanis].	33.89	422	262	11	37	449	230	643	3e-51	194
rs:WP_040041719	DNA topoisomerase III [Herbaspirillum sp. TSA66].	35.67	356	208	10	40	385	255	599	3e-51	196
rs:WP_020492503	DNA topoisomerase III [Dehalobacter sp. FTH1].	31.73	457	249	14	40	446	255	698	3e-51	195
rs:WP_032099574	DNA topoisomerase III [Anoxybacillus flavithermus].	31.70	429	261	10	36	450	244	654	4e-51	195
rs:WP_047445950	DNA topoisomerase III [Chryseobacterium sp. YR005].	31.99	422	269	10	40	459	233	638	4e-51	194
rs:WP_014930286	DNA topoisomerase III [Listeria monocytogenes].	34.15	366	223	5	37	399	229	579	4e-51	195
rs:WP_025231015	DNA topoisomerase III [Clostridium sp. ASBs410].	35.04	391	240	6	40	425	238	619	4e-51	195
tr:A0A0C7JF70_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.10	412	239	7	20	425	226	594	4e-51	194
rs:WP_039847570	DNA topoisomerase III, partial [Pseudomonas amygdali].	38.64	295	169	4	159	452	2	285	4e-51	187
rs:WP_034759989	DNA topoisomerase III [Bacillus vietnamensis].	34.20	345	204	5	61	397	259	588	4e-51	195
rs:WP_025073101	DNA topoisomerase III [Prevotella timonensis].	32.58	396	249	9	18	401	212	601	4e-51	193
rs:WP_045029767	DNA topoisomerase III [Draconibacterium sp. JN14CK-3].	32.38	383	244	9	18	399	213	581	4e-51	195
rs:WP_040949651	DNA topoisomerase III, partial [Paenibacillaceae bacterium G5].	37.14	350	176	9	31	344	220	561	4e-51	192
tr:D0LL88_HALO1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.06	363	222	6	47	400	288	638	4e-51	195
rs:WP_040441619	hypothetical protein, partial [Alicyclobacillus acidoterrestris].	32.54	418	270	8	38	453	234	641	4e-51	194
rs:WP_018341696	DNA topoisomerase III [Cytophaga aurantiaca].	32.66	447	255	11	40	454	233	665	4e-51	194
rs:WP_040103882	DNA topoisomerase III, partial [Paenibacillus polymyxa].	33.41	419	247	11	40	435	126	535	4e-51	194
tr:T0BQW9_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.59	390	253	6	38	425	234	619	4e-51	194
rs:WP_026823973	DNA topoisomerase III [Arsenophonus nasoniae].	32.51	363	232	4	31	385	239	596	4e-51	194
rs:WP_039439757	DNA topoisomerase III [Porphyromonas gulae].	35.00	380	231	10	17	392	211	578	4e-51	194
rs:WP_033918639	hypothetical protein [Enterococcus faecalis].	32.07	421	244	12	59	459	270	668	5e-51	194
rs:WP_047924141	DNA topoisomerase III [Listeria monocytogenes].	33.08	402	250	6	37	435	229	614	5e-51	194
tr:A0A0A5KV71_BURCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	35.75	358	204	8	38	385	253	594	5e-51	195
rs:WP_026808919	DNA topoisomerase III [Arenibacter latericius].	31.06	425	257	11	38	446	231	635	5e-51	195
rs:WP_046465821	DNA topoisomerase III [Staphylococcus equorum].	30.84	415	258	9	43	450	235	627	5e-51	194
rs:WP_027374258	MULTISPECIES: DNA topoisomerase III [Chryseobacterium].	32.41	432	260	11	40	449	233	654	5e-51	194
rs:WP_027089380	DNA topoisomerase III [[Clostridium] saccharogumia].	30.42	424	265	9	37	451	233	635	5e-51	194
rs:WP_014601552	DNA topoisomerase III [Listeria monocytogenes].	34.70	366	221	5	37	399	229	579	5e-51	194
rs:WP_039445782	DNA topoisomerase III [Porphyromonas gulae].	35.00	380	231	10	17	392	211	578	5e-51	194
rs:WP_003722116	DNA topoisomerase III [Listeria monocytogenes].	34.70	366	221	5	37	399	229	579	5e-51	194
rs:WP_039204385	DNA topoisomerase III, partial [Burkholderia glumae].	35.47	358	205	8	38	385	253	594	6e-51	195
rs:WP_038568657	DNA topoisomerase III [Paenibacillus odorifer].	31.53	406	248	7	36	435	231	612	6e-51	194
rs:WP_035978137	DNA topoisomerase III, partial [Burkholderia glumae].	35.47	358	205	8	38	385	253	594	6e-51	195
rs:WP_041098558	DNA topoisomerase III [Bacillus badius].	32.67	401	253	9	59	456	268	654	6e-51	194
rs:WP_025674601	DNA topoisomerase III [Paenibacillus polymyxa].	33.41	419	247	11	40	435	234	643	6e-51	194
rs:WP_031527797	DNA topoisomerase III [Dyadobacter crusticola].	32.78	418	242	12	61	454	254	656	6e-51	194
rs:WP_036060571	DNA topoisomerase III [Listeria weihenstephanensis].	34.60	367	218	6	37	399	229	577	6e-51	194
rs:WP_039175406	DNA topoisomerase III [Listeria monocytogenes].	34.70	366	221	5	37	399	229	579	6e-51	194
rs:WP_039432547	DNA topoisomerase III [Porphyromonas gulae].	35.00	380	231	10	17	392	211	578	6e-51	194
rs:WP_018965808	DNA topoisomerase III [Porphyromonas gulae].	35.00	380	231	10	17	392	211	578	6e-51	194
rs:WP_025716118	DNA topoisomerase III, partial [Paenibacillus sp. 1-18].	34.68	372	215	9	40	391	234	597	6e-51	194
rs:WP_043192735	DNA topoisomerase III, partial [Burkholderia glumae].	35.47	358	205	8	38	385	253	594	6e-51	195
rs:WP_042967424	DNA topoisomerase III, partial [Burkholderia glumae].	35.47	358	205	8	38	385	253	594	6e-51	195
rs:WP_013390829	DNA topoisomerase III [Achromobacter xylosoxidans].	35.09	379	215	10	22	385	236	598	6e-51	195
rs:WP_044478733	DNA topoisomerase III [Paenibacillus sp. GD11].	33.65	425	244	12	40	438	234	646	6e-51	194
rs:WP_015877326	DNA topoisomerase III [Burkholderia glumae].	35.47	358	205	8	38	385	253	594	6e-51	195
rs:WP_009924395	DNA topoisomerase III [Listeria monocytogenes].	34.70	366	221	5	37	399	229	579	7e-51	194
rs:WP_019533711	DNA topoisomerase III [Paenibacillus ginsengihumi].	32.71	425	242	10	38	445	234	631	7e-51	194
rs:WP_014931756	DNA topoisomerase III [Listeria monocytogenes].	34.70	366	221	5	37	399	229	579	7e-51	194
rs:WP_014601215	DNA topoisomerase III [Listeria monocytogenes].	34.70	366	221	5	37	399	229	579	7e-51	194
rs:WP_043886117	DNA topoisomerase III [Paenibacillus polymyxa].	33.41	419	247	11	40	435	234	643	7e-51	194
rs:WP_045461521	DNA topoisomerase III [Sporocytophaga myxococcoides].	33.78	376	236	9	47	420	240	604	7e-51	194
rs:WP_022075325	DNA topoisomerase [Firmicutes bacterium CAG:212].	34.57	376	219	8	69	428	262	626	7e-51	194
rs:WP_012951084	DNA topoisomerase III [Listeria monocytogenes].	34.70	366	221	5	37	399	229	579	7e-51	194
tr:H8N181_CORCM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	34.35	393	228	9	34	399	286	675	7e-51	197
rs:WP_047686041	hypothetical protein [Lactococcus lactis].	32.07	421	244	12	59	459	270	668	7e-51	194
tr:V4ZF16_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	35.75	358	204	8	38	385	233	574	8e-51	194
tr:A0A0C7GPW0_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.10	412	239	7	20	425	226	594	8e-51	194
tr:A0A0C7GEP2_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.88	415	242	7	20	428	226	597	8e-51	194
gp:HE577054_2591	DNA topoisomerase III [Paenibacillus polymyxa M1]	33.41	419	247	11	40	435	237	646	8e-51	194
rs:WP_041114323	DNA topoisomerase III [Bacillus badius].	32.67	401	253	9	59	456	268	654	8e-51	194
rs:WP_017772360	DNA topoisomerase III [Burkholderia kururiensis].	35.29	357	207	8	38	385	253	594	8e-51	195
rs:WP_011237506	DNA topoisomerase III [Aromatoleum aromaticum].	35.41	401	241	9	40	435	255	642	8e-51	194
rs:WP_014602293	DNA topoisomerase III [Listeria monocytogenes].	34.70	366	221	5	37	399	229	579	8e-51	194
rs:WP_034307594	DNA topoisomerase III [Bacillus simplex].	30.80	435	267	11	35	453	243	659	8e-51	194
rs:WP_034713734	DNA topoisomerase III [Chryseobacterium soli].	33.01	415	261	11	40	452	233	632	8e-51	194
rs:WP_043320923	ATP-dependent DNA helicase RecQ [Corallococcus coralloides].	34.35	393	228	9	34	399	281	670	8e-51	197
rs:WP_012329439	DNA topoisomerase III [Burkholderia cenocepacia].	35.75	358	204	8	38	385	253	594	8e-51	194
rs:WP_010990062	DNA topoisomerase III [Listeria monocytogenes].	34.70	366	221	5	37	399	229	579	8e-51	194
rs:WP_004583756	DNA topoisomerase III [Porphyromonas gingivalis].	32.44	450	267	15	17	446	211	643	8e-51	193
rs:WP_011546488	DNA topoisomerase III [Burkholderia cenocepacia].	35.75	358	204	8	38	385	253	594	8e-51	194
tr:A2VUF6_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	35.75	358	204	8	38	385	276	617	9e-51	194
rs:WP_018933466	hypothetical protein [Gracilibacillus lacisalsi].	31.47	394	248	6	38	425	235	612	9e-51	194
rs:WP_019913667	DNA topoisomerase III [Paenibacillus sp. HW567].	32.84	408	237	9	38	435	233	613	9e-51	194
rs:WP_017722920	DNA topoisomerase III [Staphylococcus xylosus].	30.29	416	259	8	43	450	235	627	9e-51	194
tr:A0A0C7G6G8_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.10	412	239	7	20	425	226	594	9e-51	193
tr:A4T0M8_POLSQ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.49	437	243	12	38	439	255	674	9e-51	194
rs:WP_023988966	DNA topoisomerase III [Paenibacillus polymyxa].	33.60	372	219	9	40	391	234	597	9e-51	194
rs:WP_006209708	DNA topoisomerase III [Paenibacillus vortex].	32.09	402	230	12	40	411	234	622	9e-51	194
rs:WP_022269543	DNA topoisomerase [Firmicutes bacterium CAG:424].	33.33	366	225	7	51	406	243	599	9e-51	194
rs:WP_019418265	DNA topoisomerase III [Anoxybacillus kamchatkensis].	31.03	435	262	11	36	453	244	657	1e-50	193
rs:WP_027471632	DNA topoisomerase III [Saccharicrinis fermentans].	29.87	452	285	13	18	454	212	646	1e-50	194
tr:A0A0C7S3W2_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.88	415	242	7	20	428	226	597	1e-50	193
rs:WP_047981750	DNA topoisomerase III [Ornithinibacillus contaminans].	32.54	378	240	5	24	396	225	592	1e-50	193
rs:WP_038562834	DNA topoisomerase III [Draconibacterium orientale].	32.11	383	245	9	18	399	213	581	1e-50	194
rs:WP_019533739	DNA topoisomerase III [Paenibacillus ginsengihumi].	32.98	382	223	11	34	391	228	600	1e-50	194
rs:WP_036613668	DNA topoisomerase III [Paenibacillus sp. FSL H7-689].	33.42	392	222	9	34	398	228	607	1e-50	194
rs:WP_025916648	DNA topoisomerase III, partial [Herminiimonas sp. CN].	34.55	356	210	9	40	385	22	364	1e-50	193
tr:F8F8M0_PAEMK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.69	392	217	10	34	396	228	609	1e-50	196
rs:WP_006717210	DNA topoisomerase III [Desulfitobacterium metallireducens].	33.78	373	222	7	42	392	273	642	1e-50	194
rs:WP_014008078	DNA topoisomerase III [Collimonas fungivorans].	32.75	397	243	9	40	426	255	637	1e-50	194
rs:WP_036673825	DNA topoisomerase III [Paenibacillus sp. FSL R5-192].	33.77	385	216	9	34	391	228	600	1e-50	194
tr:A0A0C7PZI4_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.10	412	239	7	20	425	226	594	1e-50	193
tr:A0A0C7I5H8_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.10	412	239	7	20	425	226	594	1e-50	193
rs:WP_021989105	DNA topoisomerase III [Odoribacter sp. CAG:788].	29.84	429	264	11	37	446	230	640	1e-50	193
rs:WP_040053214	DNA topoisomerase III [Burkholderia sp. MR1].	35.44	364	197	10	38	385	253	594	1e-50	194
rs:WP_041847283	DNA topoisomerase III [Bacillus thermoamylovorans].	31.75	400	243	10	57	446	268	647	1e-50	193
rs:WP_002822851	DNA topoisomerase III, partial [Campylobacter coli].	31.81	415	255	9	32	428	233	637	1e-50	192
rs:WP_016313465	DNA topoisomerase III [Paenibacillus barengoltzii].	32.41	398	243	6	34	428	229	603	1e-50	193
rs:WP_006464583	DNA topoisomerase III [Herbaspirillum frisingense].	34.37	355	215	7	40	385	255	600	1e-50	194
rs:WP_039419614	DNA topoisomerase III [Porphyromonas gulae].	34.74	380	232	10	17	392	211	578	1e-50	193
rs:WP_028221532	DNA topoisomerase III [Burkholderia oxyphila].	36.21	359	201	9	38	385	253	594	1e-50	194
rs:WP_039435848	DNA topoisomerase III [Porphyromonas gulae].	35.00	380	231	10	17	392	211	578	1e-50	193
rs:WP_025039084	MULTISPECIES: DNA topoisomerase III [Geobacillus].	32.35	408	242	7	40	446	234	608	1e-50	193
rs:WP_032592777	DNA topoisomerase III, partial [Campylobacter jejuni].	33.70	368	227	7	32	385	233	597	2e-50	192
rs:WP_009581364	DNA topoisomerase III [Fulvivirga imtechensis].	30.38	451	287	12	18	454	212	649	2e-50	193
tr:R9KJT4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.53	475	271	12	35	459	258	723	2e-50	194
rs:WP_024004637	DNA topoisomerase III [Advenella kashmirensis].	31.52	422	251	9	38	445	253	650	2e-50	194
rs:WP_042586599	MULTISPECIES: DNA topoisomerase III [Burkholderia].	35.47	358	205	8	38	385	253	594	2e-50	194
rs:WP_036100249	DNA topoisomerase III [Listeria riparia].	33.42	401	248	7	37	435	229	612	2e-50	193
rs:WP_036084712	DNA topoisomerase III [Listeria booriae].	33.42	401	248	7	37	435	229	612	2e-50	193
tr:U2X8N2_GEOKU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.35	408	242	7	40	446	230	604	2e-50	192
rs:WP_028211930	DNA topoisomerase III [Burkholderia mimosarum].	35.75	358	204	9	38	385	253	594	2e-50	194
rs:WP_044001639	DNA topoisomerase III [Hymenobacter swuensis].	32.00	450	262	12	30	446	245	683	2e-50	193
rs:WP_010283960	DNA topoisomerase III [Bacillus timonensis].	31.32	431	262	12	36	448	244	658	2e-50	193
rs:WP_017688080	DNA topoisomerase III [Paenibacillus sp. PAMC 26794].	33.42	392	222	9	34	398	228	607	2e-50	193
tr:Z2EZT3_VIBPH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	38.72	235	137	1	36	270	123	350	2e-50	186
rs:WP_010090307	DNA topoisomerase III [Burkholderia ubonensis].	35.47	358	205	8	38	385	253	594	2e-50	194
rs:WP_004698401	DNA topoisomerase [Veillonella parvula].	30.25	433	279	10	35	459	240	657	2e-50	192
rs:WP_028870997	DNA topoisomerase III [Psychroserpens burtonensis].	30.81	422	262	11	38	446	231	635	2e-50	193
rs:WP_042381158	DNA topoisomerase III [Geobacillus kaustophilus].	32.35	408	242	7	40	446	234	608	2e-50	192
rs:WP_041285285	DNA topoisomerase III, partial [Desulfotomaculum gibsoniae].	32.09	374	239	6	74	446	11	370	2e-50	190
rs:WP_002801286	DNA topoisomerase III, partial [Campylobacter coli].	31.81	415	255	9	32	428	233	637	2e-50	192
rs:WP_036693314	DNA topoisomerase III [Paenibacillus sp. FSL R7-269].	32.19	407	241	8	38	435	233	613	2e-50	192
rs:WP_023971603	DNA topoisomerase III, partial [Salmonella enterica].	37.35	257	153	3	36	292	251	499	2e-50	189
rs:WP_024538446	DNA topoisomerase III [Comamonas badia].	35.29	374	221	9	40	400	263	628	2e-50	194
rs:WP_038180256	DNA topoisomerase III [Viridibacillus arenosi].	34.62	338	208	4	59	391	257	586	2e-50	192
rs:WP_011367300	DNA topoisomerase III [Desulfovibrio alaskensis].	33.73	418	249	11	38	446	305	703	2e-50	193
rs:WP_046955042	DNA topoisomerase III [Bacillus cereus].	30.86	431	264	12	36	450	244	656	2e-50	192
tr:B4D958_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.14	372	223	8	40	402	252	610	2e-50	192
rs:WP_027181485	DNA topoisomerase III [Desulfovibrio alaskensis].	33.73	418	249	11	38	446	305	703	2e-50	193
rs:WP_028076707	DNA topoisomerase III [Solirubrobacterales bacterium URHD0059].	31.34	402	256	9	55	449	268	656	2e-50	193
rs:WP_011886436	MULTISPECIES: DNA topoisomerase III [Burkholderia].	35.47	358	205	8	38	385	253	594	2e-50	193
rs:WP_036093033	DNA topoisomerase III [Listeria newyorkensis].	34.25	365	222	6	37	399	229	577	2e-50	192
rs:WP_024733367	DNA topoisomerase III [Clostridiales bacterium VE202-14].	30.22	407	254	6	24	428	223	601	2e-50	192
rs:WP_033407435	DNA topoisomerase III, partial [Uliginosibacterium gangwonense].	34.24	406	239	11	40	435	255	642	2e-50	193
rs:WP_000766779	DNA topoisomerase III [Bacillus cereus].	30.86	431	264	12	36	450	244	656	2e-50	192
rs:WP_046152240	DNA topoisomerase III [Burkholderia andropogonis].	35.29	357	207	8	38	385	253	594	2e-50	194
rs:WP_024903475	DNA topoisomerase III [Burkholderia andropogonis].	35.29	357	207	8	38	385	253	594	2e-50	194
rs:WP_021159862	MULTISPECIES: DNA topoisomerase III [Burkholderia].	35.20	358	206	8	38	385	253	594	2e-50	193
tr:R4KED7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.09	374	239	6	74	446	23	382	2e-50	190
rs:WP_000766775	DNA topoisomerase III [Bacillus cereus].	30.63	431	265	12	36	450	244	656	2e-50	192
rs:WP_018755653	hypothetical protein [Paenibacillus terrigena].	33.77	385	219	10	40	396	234	610	2e-50	192
rs:WP_013523745	MULTISPECIES: DNA topoisomerase III [Geobacillus].	32.35	408	242	7	40	446	234	608	2e-50	192
rs:WP_020616882	DNA topoisomerase III [Paenibacillus daejeonensis].	33.33	408	235	11	38	435	234	614	2e-50	192
rs:WP_035065255	DNA topoisomerase III [Anoxybacillus gonensis].	31.03	435	262	11	36	453	244	657	2e-50	192
rs:WP_022823336	DNA topoisomerase III [Hymenobacter norwichensis].	31.19	452	264	13	30	446	246	685	2e-50	193
rs:WP_028562548	DNA topoisomerase III [Paenibacillus pinihumi].	32.76	406	241	8	38	435	234	615	2e-50	192
rs:WP_008879173	MULTISPECIES: DNA topoisomerase III [Geobacillus].	31.13	408	247	6	40	446	234	608	2e-50	192
rs:WP_005549947	DNA topoisomerase III [Paenibacillus alvei].	33.08	390	222	10	34	391	228	610	2e-50	192
rs:WP_047152889	DNA topoisomerase III [Aneurinibacillus tyrosinisolvens].	30.94	404	251	7	36	435	232	611	2e-50	192
tr:A0A0E9LUA5_9BACT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAO28721.1};	31.05	438	263	11	36	454	229	646	2e-50	192
rs:WP_025678387	DNA topoisomerase III, partial [Paenibacillus massiliensis].	34.05	370	219	5	33	397	230	579	2e-50	191
rs:WP_006286037	topoisomerase IA [Paenibacillus popilliae].	33.68	383	229	8	34	396	228	605	2e-50	192
rs:WP_032088751	DNA topoisomerase III [Bacillus aquimaris].	33.90	354	218	6	48	396	244	586	2e-50	192
rs:WP_000766778	DNA topoisomerase III [Bacillus cereus].	30.86	431	264	11	36	450	244	656	3e-50	192
rs:WP_021250390	DNA topoisomerase III [Thauera terpenica].	34.78	368	226	7	40	400	255	615	3e-50	193
rs:WP_044743437	DNA topoisomerase III [Anoxybacillus sp. ATCC BAA-2555].	30.70	430	268	10	38	453	246	659	3e-50	192
rs:WP_015010818	DNA topoisomerase III [Amphibacillus xylanus].	31.16	398	244	6	36	425	233	608	3e-50	192
rs:WP_048244711	DNA topoisomerase III [Burkholderia cepacia].	35.75	358	204	8	38	385	253	594	3e-50	193
sp:TOP3_BACSK	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	33.00	400	241	7	38	428	236	617	3e-50	192
tr:A0A0C7I149_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.85	412	240	7	20	425	226	594	3e-50	192
rs:WP_006416665	DNA topoisomerase III [Burkholderia multivorans].	35.20	358	206	8	38	385	253	594	3e-50	193
rs:WP_006401840	DNA topoisomerase III [Burkholderia multivorans].	35.20	358	206	8	38	385	253	594	3e-50	193
rs:WP_035063636	DNA topoisomerase III [Anoxybacillus sp. SK3-4].	30.95	433	248	10	36	459	230	620	3e-50	192
rs:WP_036878228	DNA topoisomerase III [Prevotella oryzae].	31.04	422	274	10	18	435	212	620	3e-50	192
rs:WP_002809261	DNA topoisomerase III, partial [Campylobacter coli].	31.81	415	255	9	32	428	233	637	3e-50	191
tr:K6KZQ0_KLEOX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	38.28	256	148	4	36	290	251	497	3e-50	189
rs:WP_029296993	DNA topoisomerase III [Chryseobacterium hispalense].	33.17	416	261	11	40	453	233	633	3e-50	192
rs:WP_007581951	MULTISPECIES: DNA topoisomerase III [Burkholderia].	35.20	358	206	9	38	385	253	594	3e-50	193
rs:WP_002834103	DNA topoisomerase III, partial [Campylobacter coli].	31.81	415	255	9	32	428	233	637	3e-50	191
rs:WP_046213986	DNA topoisomerase III [Paenibacillus wulumuqiensis].	34.37	387	230	10	40	408	234	614	3e-50	192
rs:WP_014195788	DNA topoisomerase III [Geobacillus thermoleovorans].	32.35	408	242	7	40	446	234	608	3e-50	192
tr:A0A0E1ZME0_CAMJU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EIB53379.1}; Flags: Fragment;	31.88	414	254	9	32	427	233	636	3e-50	191
rs:WP_003756869	DNA topoisomerase III [Listeria grayi].	33.24	352	221	3	37	385	229	569	3e-50	192
rs:WP_039790282	DNA topoisomerase III, partial [Herbaspirillum huttiense].	34.08	355	216	7	40	385	255	600	3e-50	193
rs:WP_034190221	DNA topoisomerase III [Burkholderia cenocepacia].	35.20	358	206	8	38	385	253	594	3e-50	193
rs:WP_032702136	DNA topoisomerase III, partial [Campylobacter coli].	33.70	368	227	7	32	385	233	597	3e-50	191
rs:WP_023634313	DNA topoisomerase III [Geobacillus sp. MAS1].	32.35	408	242	7	40	446	234	608	3e-50	192
tr:A0A0A1S5R5_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.10	412	239	7	20	425	226	594	3e-50	192
rs:WP_002506961	DNA topoisomerase III [Staphylococcus sp. OJ82].	30.60	415	259	9	43	450	235	627	4e-50	192
rs:WP_042305031	DNA topoisomerase III [Burkholderia terrae].	34.92	358	207	9	38	385	253	594	4e-50	193
rs:WP_039810558	DNA topoisomerase III [Jeotgalibacillus sp. D5].	32.76	406	244	12	59	456	268	652	4e-50	192
rs:WP_007781693	DNA topoisomerase III [Desulfosporosinus youngiae].	33.77	382	226	9	40	401	255	629	4e-50	192
rs:WP_018086956	hypothetical protein [Desulfurispora thermophila].	33.66	413	247	10	40	446	243	634	4e-50	192
rs:WP_019915921	DNA topoisomerase III [Methyloversatilis discipulorum].	34.75	400	233	12	40	425	255	640	4e-50	192
rs:WP_038539664	DNA topoisomerase III [Bacillus sp. X1(2014)].	30.86	418	244	9	36	446	230	609	4e-50	191
rs:WP_027409811	DNA topoisomerase III [Anoxybacillus tepidamans].	30.56	432	270	11	36	453	244	659	4e-50	192
rs:WP_042200915	DNA topoisomerase III [Paenibacillus sp. G4].	31.45	407	244	8	38	435	233	613	4e-50	192
rs:WP_047899336	DNA topoisomerase III [Burkholderia pyrrocinia].	34.17	357	211	7	38	385	253	594	4e-50	192
rs:WP_043019033	DNA topoisomerase III, partial [Campylobacter jejuni].	33.70	368	227	7	32	385	233	597	4e-50	191
rs:WP_027409388	DNA topoisomerase III [Anoxybacillus tepidamans].	30.79	406	240	6	36	435	230	600	4e-50	191
tr:B2JJU0_BURP8	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	35.20	358	206	9	38	385	275	616	4e-50	193
rs:WP_047986890	DNA topoisomerase III [Bacillus pseudalcaliphilus].	32.27	406	251	8	36	435	234	621	4e-50	192
rs:WP_036649449	DNA topoisomerase III [Paenibacillus pini].	32.11	408	241	8	39	435	234	616	4e-50	191
rs:WP_010345965	DNA topoisomerase III [Paenibacillus peoriae].	34.37	419	243	11	40	435	234	643	4e-50	192
rs:WP_028363905	DNA topoisomerase III [Burkholderia sp. UYPR1.413].	35.20	358	206	9	38	385	253	594	4e-50	192
rs:WP_043020510	DNA topoisomerase III, partial [Campylobacter jejuni].	33.70	368	227	7	32	385	233	597	4e-50	191
rs:WP_040994040	DNA topoisomerase III [Chryseobacterium oranimense].	32.21	416	266	9	40	453	233	634	4e-50	191
rs:WP_036638054	DNA topoisomerase III [Paenibacillus sp. FSL R5-808].	31.84	402	231	12	40	411	234	622	5e-50	192
rs:WP_035783947	DNA topoisomerase [Butyrivibrio sp. MC2021].	32.18	432	250	12	47	446	270	690	5e-50	194
rs:WP_002839589	DNA topoisomerase III, partial [Campylobacter coli].	31.57	415	256	9	32	428	233	637	5e-50	191
rs:WP_005881848	DNA topoisomerase III [Oxalobacter formigenes].	33.99	356	214	8	40	385	255	599	5e-50	192
rs:WP_042172682	DNA topoisomerase III [Paenibacillus sp. FSL R7-0331].	31.45	407	244	8	38	435	233	613	5e-50	191
rs:WP_022927631	DNA topoisomerase III [Patulibacter americanus].	31.34	434	258	11	37	449	256	670	5e-50	192
rs:WP_006763069	MULTISPECIES: DNA topoisomerase III [Burkholderia cepacia complex].	35.47	358	205	8	38	385	253	594	5e-50	192
rs:WP_010521506	DNA topoisomerase III [Flavobacteriaceae bacterium HQM9].	29.89	435	272	12	38	454	231	650	5e-50	192
rs:WP_012575131	DNA topoisomerase III [Anoxybacillus flavithermus].	31.26	435	261	11	36	453	244	657	5e-50	191
rs:WP_036680927	DNA topoisomerase III [Paenibacillus sp. FSL H8-237].	31.28	406	249	7	36	435	231	612	5e-50	191
rs:WP_028540227	DNA topoisomerase III [Paenibacillus sp. J14].	32.41	398	243	6	34	428	229	603	5e-50	191
rs:WP_023945960	DNA topoisomerase III [Helicobacter fennelliae].	30.91	440	275	8	32	459	237	659	5e-50	191
rs:WP_041655760	DNA topoisomerase III [Azoarcus sp. KH32C].	34.96	369	223	8	40	400	255	614	5e-50	192
rs:WP_009222685	DNA topoisomerase III [Peptoniphilus sp. oral taxon 386].	30.50	400	248	6	47	436	243	622	5e-50	191
rs:WP_041763180	DNA topoisomerase III [Burkholderia phymatum].	35.20	358	206	9	38	385	253	594	5e-50	192
rs:WP_027951620	DNA topoisomerase III [Hallella seregens].	33.70	362	212	13	51	398	245	592	5e-50	191
rs:WP_033607002	hypothetical protein, partial [Enterococcus faecium].	31.12	421	250	11	52	455	134	531	5e-50	190
rs:WP_032597331	DNA topoisomerase III, partial [Campylobacter jejuni].	33.70	368	227	7	32	385	233	597	5e-50	191
rs:WP_016343946	DNA topoisomerase [Burkholderia sp. RPE64].	34.54	359	207	8	38	385	253	594	5e-50	192
rs:WP_022739163	DNA topoisomerase III [Laceyella sacchari].	30.23	430	268	10	38	454	241	651	6e-50	191
rs:WP_000766760	DNA topoisomerase III [Bacillus cereus].	33.80	355	218	8	36	385	244	586	6e-50	191
rs:WP_035523344	DNA topoisomerase III [Burkholderia sacchari].	35.47	358	205	9	38	385	253	594	6e-50	192
rs:WP_015374805	DNA topoisomerase III [Geobacillus sp. GHH01].	31.62	408	245	6	40	446	234	608	6e-50	191
rs:WP_000766751	DNA topoisomerase III [Bacillus cereus].	30.61	428	265	11	36	448	244	654	6e-50	191
rs:WP_007430622	DNA topoisomerase III [Paenibacillus sp. Aloe-11].	34.37	419	243	11	40	435	234	643	6e-50	192
rs:WP_027449112	DNA topoisomerase III [Prevotella brevis].	31.30	409	259	11	18	414	212	610	6e-50	191
rs:WP_017450116	MULTISPECIES: DNA topoisomerase III [Herbaspirillum].	34.37	355	215	7	40	385	255	600	6e-50	192
rs:WP_027793206	DNA topoisomerase III [Burkholderia acidipaludis].	35.75	358	204	9	38	385	253	594	6e-50	192
tr:H0PYH2_9RHOO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.96	369	223	8	40	400	264	623	6e-50	192
rs:WP_027785766	DNA topoisomerase III [Burkholderia cepacia].	33.89	357	212	7	38	385	253	594	6e-50	192
tr:F9MPK7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	40.25	236	134	3	74	308	3	232	6e-50	181
rs:WP_028203227	DNA topoisomerase III [Burkholderia nodosa].	35.47	358	205	9	38	385	253	594	6e-50	192
rs:WP_034179361	DNA topoisomerase III [Burkholderia pyrrocinia].	35.20	358	206	8	38	385	253	594	6e-50	192
rs:WP_036082282	DNA topoisomerase III [Listeria cornellensis].	33.97	365	223	6	37	399	229	577	6e-50	191
rs:WP_020162915	DNA topoisomerase III [Methyloversatilis discipulorum].	34.51	397	238	10	40	425	255	640	6e-50	192
rs:WP_015555481	DNA topoisomerase [Taylorella equigenitalis].	35.81	363	200	9	38	385	253	597	6e-50	192
rs:WP_027454557	DNA topoisomerase III [Prevotella brevis].	32.20	410	254	13	18	414	212	610	6e-50	191
rs:WP_013145350	DNA topoisomerase III [Geobacillus sp. C56-T3].	32.35	408	242	7	40	446	234	608	6e-50	191
rs:WP_038585649	DNA topoisomerase III [Paenibacillus sp. FSL H7-0357].	31.94	407	242	8	38	435	233	613	7e-50	191
rs:WP_036881990	DNA topoisomerase III [Prevotella disiens].	32.71	376	227	12	37	398	235	598	7e-50	190
rs:WP_045499150	DNA topoisomerase III [Chryseobacterium sp. StRB126].	31.94	432	262	11	40	449	233	654	7e-50	191
rs:WP_011689341	ATP-dependent DNA helicase RecQ [Candidatus Solibacter usitatus].	34.70	366	226	6	43	398	263	625	7e-50	194
rs:WP_021589015	DNA topoisomerase III [Prevotella baroniae].	33.59	384	227	11	37	402	230	603	7e-50	190
rs:WP_021846108	DNA topoisomerase [Blautia hydrogenotrophica CAG:147].	33.00	400	253	6	36	428	229	620	7e-50	191
rs:WP_025881445	DNA topoisomerase III [Prevotella baroniae].	33.59	384	227	11	37	402	230	603	7e-50	190
rs:WP_026067918	DNA topoisomerase III [Pusillimonas noertemannii].	35.36	362	205	10	38	385	251	597	7e-50	192
rs:WP_000766753	DNA topoisomerase III [Bacillus cereus].	30.47	430	267	11	36	450	244	656	7e-50	191
rs:WP_048013114	DNA topoisomerase III [Bacillus marisflavi].	33.78	370	217	6	38	396	233	585	7e-50	191
rs:WP_011353576	DNA topoisomerase III [Burkholderia lata].	34.92	358	207	8	38	385	253	594	7e-50	192
rs:WP_000766748	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.47	430	267	11	36	450	244	656	7e-50	191
rs:WP_036210415	DNA topoisomerase III [Massilia sp. LC238].	34.31	376	220	10	22	385	237	597	8e-50	192
rs:WP_014895687	DNA topoisomerase III [Burkholderia cepacia].	35.20	358	206	8	38	385	253	594	8e-50	192
rs:WP_039353751	DNA topoisomerase III [Burkholderia contaminans].	34.92	358	207	8	38	385	253	594	8e-50	192
rs:WP_000766747	DNA topoisomerase III [Bacillus cereus].	30.47	430	267	11	36	450	244	656	8e-50	191
rs:WP_022171745	DNA topoisomerase [Blautia sp. CAG:52].	35.19	341	210	6	61	394	257	593	8e-50	191
rs:WP_048003960	DNA topoisomerase III [Bacillus marisflavi].	33.78	370	217	6	38	396	233	585	8e-50	191
rs:WP_000766749	DNA topoisomerase III [Bacillus thuringiensis].	30.47	430	267	10	36	450	244	656	8e-50	191
rs:WP_000766776	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.39	431	266	12	36	450	244	656	8e-50	191
rs:WP_000766759	DNA topoisomerase III [Bacillus cereus].	30.63	431	265	11	36	450	244	656	8e-50	191
rs:WP_016726768	DNA topoisomerase III [Ralstonia solanacearum].	34.74	403	229	13	38	425	253	636	8e-50	192
rs:WP_016722609	DNA topoisomerase III [Ralstonia solanacearum].	34.74	403	229	13	38	425	253	636	8e-50	192
rs:WP_047863832	hypothetical protein [Rubrobacter aplysinae].	31.88	414	255	10	29	423	240	645	8e-50	191
rs:WP_016088351	DNA topoisomerase III [Bacillus cereus].	30.63	431	265	11	36	450	244	656	8e-50	191
rs:WP_047895333	DNA topoisomerase III [Burkholderia glathei].	32.75	400	238	11	38	426	253	632	8e-50	192
rs:WP_038798357	DNA topoisomerase III [Burkholderia pseudomallei].	33.89	357	212	7	38	385	253	594	8e-50	192
rs:WP_031444327	DNA topoisomerase III [Arenibacter algicola].	31.35	386	250	8	17	401	211	582	8e-50	191
rs:WP_035417998	hypothetical protein, partial [Ferrovum myxofaciens].	34.01	344	207	7	38	377	243	570	9e-50	189
rs:WP_021948190	DNA topoisomerase III [Prevotella sp. CAG:1124].	31.91	398	252	11	18	406	212	599	9e-50	191
rs:WP_046331014	DNA topoisomerase III [Polynucleobacter necessarius].	32.27	437	244	12	38	439	271	690	9e-50	192
rs:WP_000766780	DNA topoisomerase III [Bacillus cereus].	30.63	431	265	12	36	450	244	656	9e-50	191
rs:WP_018412454	DNA topoisomerase III [Methyloversatilis thermotolerans].	34.51	397	238	10	40	425	255	640	9e-50	191
rs:WP_033004773	DNA topoisomerase III [Geobacillus sp. WSUCF1].	32.11	408	243	7	40	446	234	608	9e-50	191
rs:WP_034201218	DNA topoisomerase III [Burkholderia cepacia].	33.89	357	212	7	38	385	253	594	9e-50	191
rs:WP_024990268	DNA topoisomerase III [Prevotella albensis].	32.06	393	244	11	18	396	212	595	9e-50	191
rs:WP_048015576	DNA topoisomerase III [Bacillus marisflavi].	33.78	370	217	6	38	396	233	585	9e-50	191
rs:WP_022249592	DNA topoisomerase III [Eubacterium sp. CAG:274].	30.14	428	273	8	37	452	232	645	9e-50	191
rs:WP_043299896	DNA topoisomerase III [Burkholderia sp. TSV202].	33.89	357	212	7	38	385	253	594	9e-50	191
rs:WP_004523103	DNA topoisomerase III [Burkholderia pseudomallei].	33.89	357	212	7	38	385	253	594	9e-50	191
rs:WP_033843881	DNA topoisomerase III [Geobacillus subterraneus].	31.08	415	245	8	40	450	234	611	1e-49	191
rs:WP_042266102	DNA topoisomerase III [Burkholderia heleia].	35.47	358	205	9	38	385	253	594	1e-49	192
tr:S7UCG1_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.11	408	243	7	40	446	243	617	1e-49	191
rs:WP_005944631	DNA topoisomerase III [Blautia hydrogenotrophica].	34.22	377	233	6	59	428	252	620	1e-49	191
rs:WP_003465183	DNA topoisomerase III [Gracilibacillus halophilus].	30.75	413	231	8	36	425	233	613	1e-49	191
rs:WP_014184172	DNA topoisomerase III [Desulfosporosinus orientis].	31.56	450	255	12	36	446	251	686	1e-49	191
rs:WP_011850901	DNA topoisomerase III [Burkholderia pseudomallei].	33.89	357	212	7	38	385	253	594	1e-49	191
rs:WP_004525850	MULTISPECIES: DNA topoisomerase III [Burkholderia].	33.89	357	212	7	38	385	253	594	1e-49	191
rs:WP_036864764	DNA topoisomerase III [Porphyromonas sp. COT-108 OH2963].	29.30	430	287	10	22	446	218	635	1e-49	190
rs:WP_038781805	DNA topoisomerase III [Burkholderia pseudomallei].	33.89	357	212	7	38	385	253	594	1e-49	191
rs:WP_035987223	DNA topoisomerase III [Burkholderia caribensis].	34.92	358	207	9	38	385	253	594	1e-49	191
rs:WP_025682658	DNA topoisomerase III [Paenibacillus sp. 1-49].	34.95	372	214	9	40	391	234	597	1e-49	191
rs:WP_009962376	DNA topoisomerase III [Burkholderia pseudomallei].	33.89	357	212	7	38	385	253	594	1e-49	191
tr:D8P0T1_RALSL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.58	402	226	13	38	425	253	631	1e-49	191
rs:WP_002872081	DNA topoisomerase III, partial [Campylobacter jejuni].	31.57	415	256	9	32	428	233	637	1e-49	190
rs:WP_009927580	DNA topoisomerase III [Burkholderia pseudomallei].	33.89	357	212	7	38	385	253	594	1e-49	191
rs:WP_009520786	DNA topoisomerase III [Ralstonia sp. PBA].	35.18	361	206	10	38	387	253	596	1e-49	191
rs:WP_038784157	DNA topoisomerase III [Burkholderia pseudomallei].	33.89	357	212	7	38	385	253	594	1e-49	191
rs:WP_006299012	DNA topoisomerase III [Hylemonella gracilis].	34.68	372	225	7	40	400	262	626	1e-49	192
rs:WP_025064416	DNA topoisomerase III [Prevotella disiens].	32.71	376	227	12	37	398	235	598	1e-49	189
tr:A0A0B0I044_9BACL	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:KHF34212.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KHF34212.1};	32.63	380	226	9	34	391	228	599	1e-49	191
rs:WP_013236594	DNA topoisomerase III [Herbaspirillum seropedicae].	34.08	355	216	7	40	385	255	600	1e-49	191
tr:A0A0C7NXC2_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.19	414	236	8	20	425	226	594	1e-49	190
rs:WP_035230495	DNA topoisomerase III [Desulfobulbus sp. Tol-SR].	34.34	364	213	9	22	373	243	592	1e-49	191
rs:WP_043293089	DNA topoisomerase III, partial [Burkholderia vietnamiensis].	39.68	315	167	7	74	377	290	592	1e-49	191
rs:WP_012160000	DNA topoisomerase III [Alkaliphilus oremlandii].	32.03	409	246	9	37	427	233	627	1e-49	191
rs:WP_034339994	DNA topoisomerase III [Herbaspirillum sp. B39].	34.08	355	216	7	40	385	255	600	1e-49	191
tr:A4JV87_BURVG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	39.68	315	167	7	74	377	290	592	1e-49	191
tr:U2JF73_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERJ78677.1};	32.71	376	227	12	37	398	251	614	1e-49	190
rs:WP_004200734	MULTISPECIES: DNA topoisomerase III [pseudomallei group].	33.89	357	212	7	38	385	253	594	1e-49	191
rs:WP_038729298	DNA topoisomerase III [Burkholderia pseudomallei].	33.89	357	212	7	38	385	253	594	1e-49	191
rs:WP_036847223	DNA topoisomerase III [Porphyromonas sp. COT-108 OH1349].	29.30	430	287	10	22	446	218	635	1e-49	190
rs:WP_044188831	DNA topoisomerase III [Porphyromonas sp. COT-290 OH860].	32.54	421	260	11	38	446	235	643	1e-49	190
rs:WP_038758558	DNA topoisomerase III [Burkholderia pseudomallei].	33.89	357	212	7	38	385	253	594	1e-49	191
rs:WP_019717336	DNA topoisomerase III [Ralstonia solanacearum].	34.74	403	229	13	38	425	253	636	1e-49	191
rs:WP_024430099	DNA topoisomerase III [Burkholderia pseudomallei].	33.89	357	212	7	38	385	253	594	1e-49	191
rs:WP_038793625	DNA topoisomerase III [Burkholderia pseudomallei].	33.89	357	212	7	38	385	253	594	1e-49	191
rs:WP_008333592	DNA topoisomerase III [Herbaspirillum sp. GW103].	34.08	355	216	7	40	385	255	600	1e-49	191
rs:WP_009979581	DNA topoisomerase III [Burkholderia pseudomallei].	33.89	357	212	7	38	385	253	594	1e-49	191
rs:WP_004537740	DNA topoisomerase III [Burkholderia pseudomallei].	33.89	357	212	7	38	385	253	594	1e-49	191
rs:WP_000766761	DNA topoisomerase III [Bacillus cereus].	33.80	355	218	8	36	385	244	586	1e-49	190
rs:WP_043275216	DNA topoisomerase III [Burkholderia pseudomallei].	33.89	357	212	7	38	385	253	594	1e-49	191
rs:WP_040142560	DNA topoisomerase III [Burkholderia cenocepacia].	34.92	358	207	8	38	385	253	594	1e-49	191
rs:WP_033958343	DNA topoisomerase III [Psychroserpens jangbogonensis].	30.81	383	246	8	38	412	231	602	1e-49	191
rs:WP_034965253	DNA topoisomerase III [Epilithonimonas sp. FH1].	32.94	425	259	9	40	449	233	646	1e-49	190
rs:WP_044847346	DNA topoisomerase III [Burkholderia sp. USM B20].	34.92	358	207	8	38	385	253	594	1e-49	191
rs:WP_021963596	DNA topoisomerase III [Prevotella sp. CAG:1185].	33.98	362	221	9	54	406	247	599	1e-49	190
rs:WP_004189734	DNA topoisomerase III [Burkholderia mallei].	33.89	357	212	7	38	385	253	594	1e-49	191
rs:WP_006485782	DNA topoisomerase III [Burkholderia cenocepacia].	34.92	358	207	8	38	385	233	574	1e-49	191
rs:WP_006024093	MULTISPECIES: DNA topoisomerase III [Burkholderia].	34.92	358	207	8	38	385	253	594	1e-49	191
rs:WP_022163221	DNA topoisomerase III [Bacteroides sp. CAG:633].	31.91	376	238	9	29	397	258	622	1e-49	190
rs:WP_035066549	DNA topoisomerase III [Anoxybacillus gonensis].	30.98	439	240	11	36	459	230	620	1e-49	190
rs:WP_038773172	DNA topoisomerase III [Burkholderia pseudomallei].	33.89	357	212	7	38	385	253	594	1e-49	191
rs:WP_033025373	DNA topoisomerase III [Geobacillus sp. CAMR5420].	32.35	408	242	7	40	446	234	608	1e-49	190
rs:WP_036048796	MULTISPECIES: DNA topoisomerase III [Burkholderia].	34.92	358	207	8	38	385	253	594	1e-49	191
rs:WP_036039160	DNA topoisomerase III [Burkholderia gladioli].	34.92	358	207	8	38	385	253	594	1e-49	191
rs:WP_008352195	MULTISPECIES: DNA topoisomerase III [Burkholderia].	33.98	359	209	8	38	385	253	594	1e-49	191
rs:WP_034470315	DNA topoisomerase III [Burkholderia zhejiangensis].	33.98	359	209	8	38	385	253	594	1e-49	191
rs:WP_027788846	MULTISPECIES: DNA topoisomerase III [Burkholderia cepacia complex].	34.92	358	207	8	38	385	253	594	1e-49	191
tr:C7LTI8_DESBD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.89	392	234	9	50	435	253	617	1e-49	189
rs:WP_015602408	DNA topoisomerase III family protein [Burkholderia thailandensis].	34.92	358	207	8	38	385	253	594	1e-49	191
rs:WP_002826426	DNA topoisomerase III, partial [Campylobacter coli].	31.33	415	257	9	32	428	233	637	1e-49	189
rs:WP_034757415	DNA topoisomerase III [Chryseobacterium sp. OV259].	32.33	430	259	14	40	449	233	650	1e-49	190
rs:WP_034208701	DNA topoisomerase III [Burkholderia cepacia].	34.92	358	207	8	38	385	253	594	1e-49	191
rs:WP_042775760	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	29.61	385	251	3	35	404	245	624	1e-49	189
tr:A0A0A8VKA8_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.88	415	242	7	20	428	226	597	1e-49	190
rs:WP_010113203	DNA topoisomerase III [Burkholderia oklahomensis].	34.17	357	211	7	38	385	253	594	1e-49	191
rs:WP_028043112	DNA topoisomerase III [Candidatus Stoquefichus massiliensis].	31.09	402	263	5	37	435	233	623	1e-49	190
tr:G3A3B1_9RALS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.58	402	226	13	38	425	253	631	1e-49	191
rs:WP_022230861	DNA topoisomerase 3 (DNA topoisomerase III) [Firmicutes bacterium CAG:41].	33.58	405	220	11	71	452	287	665	1e-49	191
rs:WP_036132497	DNA topoisomerase III [Listeriaceae bacterium FSL A5-0209].	34.33	367	219	7	37	399	229	577	1e-49	190
rs:WP_014749157	DNA topoisomerase III [Advenella kashmirensis].	31.44	423	250	9	38	445	253	650	1e-49	191
rs:WP_036120904	DNA topoisomerase III [Mangrovimonas yunxiaonensis].	31.91	423	255	13	38	446	231	634	1e-49	190
tr:H5SNX8_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.67	392	241	9	40	425	261	639	1e-49	191
tr:R2RSK6_ENTCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.67	420	249	11	52	455	270	667	2e-49	190
rs:WP_021094594	MULTISPECIES: DNA topoisomerase III [Anoxybacillus].	31.48	432	264	11	36	453	244	657	2e-49	190
rs:WP_000766750	DNA topoisomerase III [Bacillus cereus].	33.62	354	220	7	36	385	244	586	2e-49	190
rs:WP_028910324	DNA topoisomerase III [Prevotella sp. AGR2160].	29.69	448	266	13	37	446	230	666	2e-49	190
rs:WP_038787866	DNA topoisomerase III [Burkholderia pseudomallei].	33.89	357	212	7	38	385	253	594	2e-49	191
tr:G2ZP25_9RALS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.58	402	226	13	38	425	253	631	2e-49	191
rs:WP_011658238	DNA topoisomerase III [Burkholderia ambifaria].	34.92	358	207	8	38	385	253	594	2e-49	191
rs:WP_025150038	DNA topoisomerase III [Bacillus sp. H1a].	30.39	431	266	11	36	450	244	656	2e-49	190
rs:WP_038748593	DNA topoisomerase III [Burkholderia pseudomallei].	34.17	357	211	7	38	385	253	594	2e-49	191
rs:WP_041485226	DNA topoisomerase III [beta proteobacterium CB].	32.21	447	250	13	29	439	239	668	2e-49	191
tr:A0A070C158_BURCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.61	357	213	7	38	385	253	594	2e-49	191
rs:WP_012492332	MULTISPECIES: DNA topoisomerase III [Burkholderia cepacia complex].	34.92	358	207	8	38	385	253	594	2e-49	191
rs:WP_028818553	DNA topoisomerase III [beta proteobacterium SCGC AAA027-C02].	32.27	437	244	12	38	439	264	683	2e-49	191
rs:WP_006750079	DNA topoisomerase III [Burkholderia ambifaria].	34.92	358	207	8	38	385	253	594	2e-49	191
rs:WP_012365004	DNA topoisomerase III [Burkholderia ambifaria].	34.92	358	207	8	38	385	253	594	2e-49	191
rs:WP_018478536	DNA topoisomerase III [Pontibacter roseus].	31.27	403	260	10	18	414	212	603	2e-49	190
rs:WP_038762203	DNA topoisomerase III [Burkholderia pseudomallei].	34.45	357	210	9	38	385	253	594	2e-49	191
rs:WP_047172050	DNA topoisomerase III [Staphylococcus xylosus].	29.98	417	259	8	43	450	235	627	2e-49	190
rs:WP_039429215	DNA topoisomerase III [Porphyromonas sp. COT-052 OH4946].	34.47	380	233	10	17	392	211	578	2e-49	189
rs:WP_034695777	DNA topoisomerase [Enterococcus casseliflavus].	31.67	420	249	11	52	455	264	661	2e-49	190
rs:WP_010100721	DNA topoisomerase III [Burkholderia oklahomensis].	34.17	357	211	7	38	385	253	594	2e-49	191
tr:A3NQ18_BURP0	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.89	357	212	7	38	385	290	631	2e-49	191
tr:M5U4I0_9PLAN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.63	361	222	8	47	404	266	615	2e-49	190
tr:Q3JXE5_BURP1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.89	357	212	7	38	385	289	630	2e-49	191
rs:WP_014281498	DNA topoisomerase III [Paenibacillus terrae].	34.37	419	243	11	40	435	234	643	2e-49	190
rs:WP_014618279	DNA topoisomerase III [Ralstonia solanacearum].	34.65	404	226	13	38	425	253	634	2e-49	191
rs:WP_031356953	DNA topoisomerase III [Burkholderia sordidicola].	32.48	428	253	13	38	451	253	658	2e-49	191
tr:B1HHD0_BURPE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.89	357	212	7	38	385	290	631	2e-49	191
rs:WP_026045275	DNA topoisomerase III [Burkholderia pyrrocinia].	33.89	357	212	7	38	385	253	594	2e-49	191
rs:WP_028227275	DNA topoisomerase III [Burkholderia ferrariae].	35.75	358	204	9	38	385	253	594	2e-49	191
rs:WP_003264700	DNA topoisomerase III [Ralstonia solanacearum].	34.65	404	226	13	38	425	253	634	2e-49	191
rs:WP_009893647	DNA topoisomerase III [Burkholderia thailandensis].	34.92	358	207	8	38	385	253	594	2e-49	191
rs:WP_004890695	DNA topoisomerase III [Anoxybacillus flavithermus].	30.80	435	263	11	36	453	244	657	2e-49	190
rs:WP_031399650	MULTISPECIES: DNA topoisomerase III [Burkholderia].	33.61	357	213	7	38	385	253	594	2e-49	191
rs:WP_043947600	DNA topoisomerase III [Ralstonia solanacearum].	34.65	404	226	13	38	425	253	634	2e-49	191
rs:WP_033125471	DNA topoisomerase III [Eubacterium sp. ER2].	34.43	395	248	6	40	430	236	623	2e-49	190
rs:WP_011831764	DNA topoisomerase [Methylibium petroleiphilum].	32.69	416	241	8	36	432	247	642	2e-49	190
rs:WP_019721177	DNA topoisomerase III [Bacillus coagulans].	30.82	451	272	13	18	446	222	654	2e-49	190
rs:WP_029141629	DNA topoisomerase III [Bacillus coagulans].	31.26	451	270	14	18	446	222	654	2e-49	189
tr:M1T6W7_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.21	447	250	13	29	439	261	690	2e-49	191
rs:WP_042590295	DNA topoisomerase III [Ralstonia solanacearum].	34.65	404	226	13	38	425	253	634	2e-49	191
rs:WP_007840343	MULTISPECIES: DNA topoisomerase III [Chryseobacterium].	31.78	428	264	10	40	449	233	650	2e-49	189
rs:WP_044302118	DNA topoisomerase [Rhodopirellula sallentina].	34.63	361	222	8	47	404	257	606	2e-49	190
rs:WP_047777856	DNA topoisomerase III [[Eubacterium] fissicatena].	34.43	366	226	6	68	425	260	619	2e-49	189
rs:WP_013207290	DNA topoisomerase III [Ralstonia solanacearum].	34.65	404	226	13	38	425	253	634	2e-49	191
rs:WP_017921309	DNA topoisomerase III [Burkholderia gladioli].	34.64	358	208	8	38	385	253	594	2e-49	191
rs:WP_009908309	DNA topoisomerase III [Burkholderia thailandensis].	34.92	358	207	8	38	385	253	594	2e-49	190
tr:A0A0B5WW23_BACCO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.26	451	270	14	18	446	218	650	2e-49	189
rs:WP_042484801	DNA topoisomerase III [Alcaligenes faecalis].	33.25	379	222	9	22	385	236	598	2e-49	190
rs:WP_043944901	DNA topoisomerase III [Ralstonia solanacearum].	34.65	404	226	13	38	425	253	634	2e-49	191
rs:WP_026858958	DNA topoisomerase III [Jeotgalicoccus psychrophilus].	33.70	368	217	6	74	435	269	615	2e-49	189
rs:WP_009902112	DNA topoisomerase III [Burkholderia thailandensis].	34.92	358	207	8	38	385	253	594	2e-49	190
rs:WP_026559271	DNA topoisomerase III [Bacillus sp. J37].	30.73	436	264	12	36	452	244	660	2e-49	189
rs:WP_004357490	DNA topoisomerase III [Prevotella disiens].	32.71	376	227	12	37	398	235	598	2e-49	189
rs:WP_019429929	DNA topoisomerase III [Limnohabitans sp. Rim47].	34.60	367	221	8	45	399	266	625	2e-49	191
rs:WP_046575281	DNA topoisomerase III [Burkholderia gladioli].	34.64	358	208	8	38	385	253	594	2e-49	191
tr:A0A0C7SIW7_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.64	415	243	7	20	428	226	597	2e-49	189
rs:WP_046514894	DNA topoisomerase III [Bacillus sp. SA1-12].	31.11	434	255	15	36	448	244	654	2e-49	189
rs:WP_047843375	DNA topoisomerase III [Paenibacillus sp. VT-400].	33.16	392	223	9	34	398	228	607	2e-49	190
rs:WP_006783591	DNA topoisomerase III [Turicibacter sanguinis].	34.60	367	216	8	36	391	230	583	2e-49	189
rs:WP_041273944	hypothetical protein, partial [Desulfobacterium autotrophicum].	29.56	406	268	6	36	432	237	633	2e-49	189
rs:WP_010422921	DNA topoisomerase III [Anaerophaga thermohalophila].	30.56	445	281	12	27	454	220	653	3e-49	190
tr:A0A0C7HMD1_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.64	415	243	7	20	428	226	597	3e-49	189
rs:WP_040531935	DNA topoisomerase III, partial [Lautropia mirabilis].	34.62	390	226	12	47	425	261	632	3e-49	190
rs:WP_036656744	DNA topoisomerase III, partial [Paenibacillus larvae].	31.78	387	239	10	22	391	213	591	3e-49	189
rs:WP_013903096	DNA topoisomerase III [Ramlibacter tataouinensis].	32.05	365	226	7	47	400	270	623	3e-49	191
rs:WP_027879013	DNA topoisomerase III [Mesoflavibacter zeaxanthinifaciens].	31.25	368	238	7	38	404	231	584	3e-49	189
rs:WP_048440440	DNA topoisomerase III [Caenimonas sp. SL110].	34.07	364	220	8	47	399	275	629	3e-49	191
rs:WP_047836781	DNA topoisomerase III [Burkholderia gladioli].	34.64	358	208	8	38	385	253	594	3e-49	190
tr:A0A0A8VWD1_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.64	415	243	7	20	428	226	597	3e-49	189
rs:WP_019924412	DNA topoisomerase III [Duganella zoogloeoides].	31.07	428	277	7	22	439	237	656	3e-49	190
rs:WP_039069501	DNA topoisomerase III [Staphylococcus xylosus].	29.68	411	268	7	43	450	235	627	3e-49	189
rs:WP_039318048	DNA topoisomerase III [Burkholderia sp. A9].	33.61	357	213	7	38	385	253	594	3e-49	190
rs:WP_013699754	DNA topoisomerase III [Burkholderia gladioli].	34.64	358	208	8	38	385	253	594	3e-49	190
rs:WP_009589194	DNA topoisomerase III [Paenibacillus sp. HGF5].	31.31	396	240	10	40	411	234	621	3e-49	189
rs:WP_021848434	DNA topoisomerase III [Bacteroides sp. CAG:598].	31.65	395	255	10	29	417	258	643	3e-49	189
tr:Q2T2B5_BURTA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.92	358	207	8	38	385	275	616	3e-49	190
rs:WP_020425541	DNA topoisomerase III [Paenibacillus riograndensis].	32.11	408	240	10	38	435	233	613	3e-49	189
rs:WP_017553244	DNA topoisomerase III [Bacillus coagulans].	31.26	451	270	14	18	446	222	654	3e-49	189
tr:C0QH35_DESAH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.56	406	268	6	36	432	237	633	3e-49	190
rs:WP_038684866	hypothetical protein, partial [Rubrobacter radiotolerans].	34.37	355	220	7	47	396	251	597	3e-49	189
rs:WP_033022586	DNA topoisomerase III [Geobacillus sp. G1w1].	31.31	412	248	8	40	450	234	611	3e-49	189
rs:WP_024093897	DNA topoisomerase 3 [Paenibacillus larvae].	31.78	387	239	10	22	391	213	591	3e-49	189
rs:WP_010181876	DNA topoisomerase III [Aquimarina agarilytica].	28.25	439	281	11	38	454	231	657	3e-49	189
rs:WP_003267350	DNA topoisomerase III [Ralstonia solanacearum].	34.65	404	226	13	38	425	253	634	3e-49	190
rs:WP_044231725	DNA topoisomerase III [Porphyromonas sp. COT-290 OH3588].	31.98	419	265	10	38	446	235	643	3e-49	189
rs:WP_028860034	DNA topoisomerase III [Ralstonia solanacearum].	34.49	403	230	13	38	425	253	636	3e-49	190
rs:WP_006759746	DNA topoisomerase III [Burkholderia ambifaria].	34.92	358	207	8	38	385	253	594	3e-49	190
rs:WP_042739088	DNA topoisomerase III [Staphylococcus gallinarum].	30.62	418	255	10	43	450	235	627	3e-49	189
rs:WP_006439101	DNA topoisomerase III [[Clostridium] hiranonis].	31.13	363	214	7	41	399	241	571	3e-49	189
rs:WP_026591986	DNA topoisomerase III [Bacillus sp. UNC437CL72CviS29].	29.44	428	270	10	36	448	244	654	3e-49	189
rs:WP_035269284	DNA topoisomerase III [Alcaligenes faecalis].	34.16	363	208	9	38	385	252	598	3e-49	190
rs:WP_009463602	MULTISPECIES: DNA topoisomerase III [Alcaligenes].	34.16	363	208	9	38	385	252	598	3e-49	190
rs:WP_022243205	DNA topoisomerase [Roseburia sp. CAG:45].	29.35	477	278	12	3	446	244	694	3e-49	191
tr:W7DPX5_9LIST	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.51	367	222	6	37	399	229	577	3e-49	189
tr:W2E6N4_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.78	387	239	10	22	391	213	591	3e-49	189
rs:WP_031409582	DNA topoisomerase III [Geobacillus vulcani].	31.33	415	244	9	40	450	234	611	3e-49	189
tr:A0A0C7IWU1_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.40	415	244	7	20	428	226	597	3e-49	189
rs:WP_006947859	DNA topoisomerase III [Prevotella marshii].	32.56	387	250	8	21	402	214	594	3e-49	189
rs:WP_044748403	DNA topoisomerase III [Bacillus alveayuensis].	30.34	435	268	13	36	453	244	660	4e-49	189
rs:WP_020750047	DNA topoisomerase III [Ralstonia solanacearum].	34.74	403	229	13	38	425	253	636	4e-49	190
rs:WP_042351153	DNA topoisomerase III [Bacillus sp. G2(2012b)].	31.99	422	256	11	26	439	226	624	4e-49	189
rs:WP_006323417	DNA topoisomerase III [Anoxybacillus flavithermus].	30.57	435	264	11	36	453	244	657	4e-49	189
rs:WP_025000225	DNA topoisomerase III [Prevotella aurantiaca].	31.97	391	245	11	18	397	217	597	4e-49	188
rs:WP_034976722	DNA topoisomerase III [Epilithonimonas lactis].	32.94	425	259	10	40	449	233	646	4e-49	189
rs:WP_003144959	DNA topoisomerase III [Gemella haemolysans].	31.05	380	238	8	73	451	263	619	4e-49	189
rs:WP_028820891	DNA topoisomerase III [beta proteobacterium SCGC AAA027-I06].	34.05	373	225	8	40	399	267	631	4e-49	191
rs:WP_002977772	DNA topoisomerase III [Chryseobacterium gleum].	32.25	431	260	11	40	449	233	652	4e-49	189
rs:WP_041123572	DNA topoisomerase III [Jeotgalibacillus alimentarius].	33.24	358	223	5	43	396	238	583	4e-49	189
rs:WP_010348782	DNA topoisomerase III [Paenibacillus peoriae].	31.40	414	246	10	36	439	231	616	4e-49	189
rs:WP_025333127	DNA topoisomerase III [Paenibacillus sabinae].	32.43	407	240	8	38	435	233	613	4e-49	189
tr:A0A023X4M0_9ACTN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.37	355	220	7	47	396	251	597	4e-49	189
rs:WP_025097237	DNA topoisomerase III [Burkholderia sp. A1].	34.64	358	208	8	38	385	253	594	4e-49	190
rs:WP_045366128	DNA topoisomerase III, partial [bacterium endosymbiont of Mortierella elongata FMR23-6].	34.45	357	210	8	38	385	253	594	4e-49	189
rs:WP_003398165	DNA topoisomerase III [Anoxybacillus flavithermus].	29.93	431	273	10	36	453	244	658	4e-49	189
rs:WP_034957209	DNA topoisomerase III, partial [Glomeribacter sp. 1016415].	34.45	357	210	8	38	385	253	594	4e-49	189
rs:WP_045930539	DNA topoisomerase III [Alcaligenes faecalis].	34.16	363	208	9	38	385	252	598	4e-49	189
rs:WP_002790206	DNA topoisomerase III, partial [Campylobacter coli].	31.57	415	256	9	32	428	233	637	4e-49	188
tr:E7RZM8_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.62	390	226	12	47	425	261	632	4e-49	190
rs:WP_000766733	DNA topoisomerase III [Bacillus cereus].	30.39	431	266	11	36	450	244	656	4e-49	189
rs:WP_045450152	DNA topoisomerase III [Burkholderia sp. RPE67].	33.43	359	211	8	38	385	253	594	4e-49	190
tr:W7C7N0_LISGR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.15	328	202	3	61	385	3	319	5e-49	185
rs:WP_000766746	DNA topoisomerase III [Bacillus cereus].	30.39	431	266	11	36	450	244	656	5e-49	189
rs:WP_039421649	DNA topoisomerase III [Porphyromonas gulae].	34.47	380	233	10	17	392	211	578	5e-49	188
rs:WP_042421644	DNA topoisomerase III [Comamonas granuli].	34.82	359	215	8	54	400	277	628	5e-49	191
rs:WP_022317548	DNA topoisomerase III [Prevotella sp. P5-125].	32.06	393	250	9	24	406	217	602	5e-49	188
rs:WP_039869614	DNA topoisomerase III [Paenibacillus sp. FSL R7-0273].	32.35	408	239	10	38	435	233	613	5e-49	189
rs:WP_034645991	DNA topoisomerase III [Cellulophaga geojensis].	30.16	431	269	11	38	454	231	643	5e-49	189
rs:WP_044079817	DNA topoisomerase III [Prevotella sp. P4-65].	32.06	393	250	9	24	406	217	602	5e-49	188
rs:WP_038507278	DNA topoisomerase III [Cellulophaga lytica].	30.16	431	269	11	38	454	231	643	5e-49	189
rs:WP_008634317	DNA topoisomerase III [Bizionia argentinensis].	29.43	435	270	11	38	454	231	646	5e-49	189
rs:WP_044947481	DNA topoisomerase III [Blautia schinkii].	33.50	391	241	6	47	428	243	623	5e-49	189
rs:WP_042519962	MULTISPECIES: DNA topoisomerase III [Prevotella].	30.22	460	272	11	24	446	217	664	5e-49	188
rs:WP_026483868	DNA topoisomerase III [Alcaligenes faecalis].	34.16	363	208	9	38	385	252	598	5e-49	189
rs:WP_008445093	DNA topoisomerase 3 [Janthinobacterium sp. HH01].	33.25	400	239	11	40	426	255	639	5e-49	190
rs:WP_039345333	DNA topoisomerase III [Chryseobacterium solincola].	34.68	346	216	7	40	384	233	569	5e-49	188
tr:F0GKV0_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	34.64	358	208	8	38	385	253	594	5e-49	189
rs:WP_020156037	hypothetical protein [Caldibacillus debilis].	31.97	416	235	10	38	445	232	607	5e-49	188
rs:WP_002511446	DNA topoisomerase III [Staphylococcus equorum].	30.36	415	260	9	43	450	235	627	5e-49	188
rs:WP_022408234	DNA topoisomerase [Clostridium sp. CAG:354].	32.97	367	224	11	47	398	271	630	5e-49	188
rs:WP_012933280	DNA topoisomerase III [Conexibacter woesei].	31.33	399	260	7	55	449	267	655	5e-49	189
rs:WP_013620522	DNA topoisomerase III [Cellulophaga lytica].	30.16	431	269	11	38	454	231	643	5e-49	189
rs:WP_009362688	DNA topoisomerase III [Anoxybacillus sp. DT3-1].	31.19	436	260	12	36	453	244	657	5e-49	188
rs:WP_003800563	DNA topoisomerase III [Alcaligenes faecalis].	34.16	363	208	9	38	385	252	598	5e-49	189
rs:WP_007784264	DNA topoisomerase III [Brevibacillus sp. CF112].	30.47	430	262	13	36	446	245	656	6e-49	188
rs:WP_005833407	DNA topoisomerase III [Brevibacillus agri].	30.47	430	262	13	36	446	245	656	6e-49	188
rs:WP_036172716	DNA topoisomerase III [Massilia sp. 9096].	35.39	356	206	8	40	385	255	596	6e-49	189
rs:WP_038327617	DNA topoisomerase III, partial [beta proteobacterium SCGC AAA027-K21].	33.43	359	215	7	38	385	252	597	6e-49	189
rs:WP_010527810	DNA topoisomerase III [Thermophagus xiamenensis].	29.75	437	272	11	37	454	230	650	6e-49	189
rs:WP_048375858	DNA topoisomerase III [Bacillus sp. LK2].	30.16	431	267	11	36	450	244	656	6e-49	188
rs:WP_042124020	DNA topoisomerase III [Paenibacillus sp. FSL R5-0345].	31.20	407	248	8	36	435	231	612	6e-49	188
rs:WP_040128547	DNA topoisomerase III [Burkholderia cenocepacia].	34.64	358	208	8	38	385	253	594	6e-49	189
tr:M5QU49_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.75	439	241	11	36	459	231	621	6e-49	188
rs:WP_005878079	DNA topoisomerase III [Oxalobacter formigenes].	33.99	356	214	7	40	385	255	599	6e-49	189
rs:WP_041101310	DNA topoisomerase III, partial [Sulfuritalea hydrogenivorans].	33.16	392	244	8	40	425	255	634	6e-49	189
rs:WP_013521814	DNA topoisomerase III [Taylorella equigenitalis].	35.81	363	200	9	38	385	253	597	6e-49	189
rs:WP_046311290	DNA topoisomerase III [Pontibacter korlensis].	30.77	442	264	11	37	443	231	665	7e-49	189
rs:WP_046544168	DNA topoisomerase III [Burkholderia contaminans].	34.64	358	208	8	38	385	253	594	7e-49	189
rs:WP_047916724	DNA topoisomerase [Lactococcus piscium].	31.31	428	255	13	48	455	253	661	7e-49	188
rs:WP_043921484	DNA topoisomerase III, partial [Paenibacillus polymyxa].	32.84	341	220	7	50	385	260	596	7e-49	187
rs:WP_017152229	DNA topoisomerase III [Bacillus sp. FJAT-13831].	32.86	353	224	6	36	385	244	586	7e-49	188
rs:WP_000766765	DNA topoisomerase III [Bacillus cereus].	32.09	430	256	11	36	448	244	654	7e-49	188
rs:WP_036851975	DNA topoisomerase III [Porphyromonas macacae].	30.93	443	274	13	18	446	213	637	7e-49	188
tr:A0A0C7RF12_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.40	415	244	7	20	428	226	597	7e-49	188
rs:WP_011466216	DNA topoisomerase III [Rhodoferax ferrireducens].	35.36	362	210	10	40	385	272	625	7e-49	190
rs:WP_042506224	DNA topoisomerase III [Algibacter lectus].	30.44	427	273	11	38	454	231	643	7e-49	188
rs:WP_038529514	DNA topoisomerase III [Formosa agariphila].	30.09	432	268	11	38	454	231	643	7e-49	188
rs:WP_026557375	DNA topoisomerase III [Bacillus sp. NSP2.1].	30.47	430	262	13	36	446	245	656	7e-49	188
rs:WP_043461343	hypothetical protein, partial [Azohydromonas australica].	32.48	431	260	10	40	449	249	669	7e-49	188
rs:WP_035434243	DNA topoisomerase III [Bacillus sp. UNC322MFChir4.1].	33.62	354	220	7	36	385	244	586	7e-49	188
rs:WP_004435076	DNA topoisomerase III [Bacillus methanolicus].	32.25	431	261	11	36	446	244	663	7e-49	188
rs:WP_026334985	DNA topoisomerase III [Oxalobacteraceae bacterium AB_14].	33.25	400	239	11	40	426	255	639	7e-49	189
rs:WP_019142232	DNA topoisomerase III [Herbaspirillum massiliense].	34.27	356	213	10	40	385	255	599	7e-49	189
rs:WP_036247736	DNA topoisomerase III [Massilia sp. BSC265].	34.92	358	206	10	40	385	255	597	7e-49	189
rs:WP_038693551	DNA topoisomerase III [Paenibacillus stellifer].	32.76	409	238	8	38	435	233	615	7e-49	188
rs:WP_039417509	DNA topoisomerase III [Porphyromonas gingivalis].	31.78	450	270	14	17	446	211	643	7e-49	188
rs:WP_044648482	DNA topoisomerase III [Paenibacillus terrae].	33.02	427	247	12	40	435	234	652	7e-49	188
rs:WP_042498112	hypothetical protein, partial [Algibacter lectus].	30.44	427	273	11	38	454	231	643	8e-49	188
rs:WP_025845013	DNA topoisomerase III [Brevibacillus agri].	30.47	430	262	13	36	446	245	656	8e-49	188
rs:WP_002158311	DNA topoisomerase III [Bacillus cereus].	30.16	431	267	11	36	450	244	656	8e-49	188
rs:WP_010662622	DNA topoisomerase III [Marinilabilia salmonicolor].	30.50	459	280	13	18	454	212	653	8e-49	188
rs:WP_047389326	DNA topoisomerase III [Firmicutes bacterium ZOR0006].	32.96	358	211	7	50	394	246	587	8e-49	188
rs:WP_002200885	DNA topoisomerase III [Bacillus cereus].	30.16	431	267	11	36	450	244	656	8e-49	188
rs:WP_013859245	DNA topoisomerase III [Bacillus coagulans].	31.04	451	271	14	18	446	222	654	8e-49	188
tr:B2RH95_PORG3	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:BAG32740.1};	31.78	450	270	14	17	446	246	678	8e-49	188
rs:WP_014279833	DNA topoisomerase III [Paenibacillus terrae].	31.72	413	245	10	36	439	231	615	8e-49	188
rs:WP_025722650	DNA topoisomerase III [Paenibacillus polymyxa].	32.63	429	250	12	40	437	234	654	8e-49	188
rs:WP_015298395	DNA topoisomerase III [Prevotella dentalis].	33.43	362	213	13	51	398	245	592	8e-49	188
rs:WP_020655828	DNA topoisomerase III [Massilia niastensis].	34.92	358	206	11	40	385	255	597	8e-49	189
tr:A0A0D3LDW1_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.08	444	268	13	40	454	233	667	8e-49	188
rs:WP_012260746	DNA topoisomerase III [Bacillus weihenstephanensis].	29.77	430	270	10	36	450	244	656	8e-49	188
rs:WP_002148790	DNA topoisomerase III [Bacillus cereus].	30.16	431	267	11	36	450	244	656	8e-49	188
rs:WP_016104534	DNA topoisomerase III [Bacillus cereus].	30.16	431	267	11	36	450	244	656	8e-49	188
rs:WP_002662996	DNA topoisomerase III [Bergeyella zoohelcum].	31.65	417	258	11	54	454	247	652	9e-49	188
rs:WP_002202402	DNA topoisomerase III [Bacillus cereus].	30.16	431	267	11	36	450	244	656	9e-49	188
rs:WP_019416613	DNA topoisomerase III [Anoxybacillus kamchatkensis].	30.75	439	241	11	36	459	230	620	9e-49	187
rs:WP_000766762	DNA topoisomerase III [Bacillus cereus].	30.61	428	265	10	36	448	244	654	9e-49	188
tr:A0A0C7GXA1_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.40	415	244	7	20	428	226	597	9e-49	187
rs:WP_044875527	DNA topoisomerase III [Paenibacillus sp. IHBB 10380].	30.54	406	255	6	34	435	229	611	9e-49	188
rs:WP_011000033	DNA topoisomerase III [Ralstonia solanacearum].	34.24	403	231	13	38	425	253	636	9e-49	189
rs:WP_005237632	DNA topoisomerase [Enterococcus casseliflavus].	31.43	420	250	11	52	455	264	661	9e-49	188
tr:F9D0D7_PREDD	SubName: Full=DNA topoisomerase TopB {ECO:0000313|EMBL:EGQ16953.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EGQ16953.1};	33.43	362	213	13	51	398	280	627	1e-48	188
rs:WP_013330742	MULTISPECIES: topoisomerase IA [Enterococcus].	31.17	462	264	17	24	454	112	550	1e-48	187
rs:WP_027386103	DNA topoisomerase III [Chryseobacterium gregarium].	33.90	351	222	8	61	406	254	599	1e-48	187
rs:WP_043894029	DNA topoisomerase III [Porphyromonas gingivalis].	31.78	450	270	14	17	446	211	643	1e-48	187
rs:WP_016764011	DNA topoisomerase III [Bacillus megaterium].	31.25	400	239	7	37	435	231	595	1e-48	187
rs:WP_039832234	DNA topoisomerase III [Paenibacillus sonchi].	31.86	408	241	9	38	435	233	613	1e-48	187
rs:WP_036729935	DNA topoisomerase III, partial [Patulibacter minatonensis].	31.25	448	268	11	23	449	245	673	1e-48	188
rs:WP_036729055	DNA topoisomerase III [Peptoniphilus sp. ChDC B134].	30.00	400	250	6	47	436	243	622	1e-48	187
tr:E4LJS5_9FIRM	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:EFR40693.1};	34.20	345	201	9	112	445	2	331	1e-48	182
rs:WP_036790296	DNA topoisomerase III [Porphyromonas canoris].	29.07	430	288	10	22	446	218	635	1e-48	187
tr:Q21RE9_RHOFT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	35.36	362	210	10	40	385	287	640	1e-48	190
rs:WP_002171395	DNA topoisomerase III [Bacillus cereus].	30.16	431	267	11	36	450	244	656	1e-48	187
rs:WP_041502811	DNA topoisomerase III [Sanguibacteroides justesenii].	28.91	422	272	9	36	446	229	633	1e-48	187
rs:WP_035796762	DNA topoisomerase [Butyrivibrio sp. MB2005].	30.69	479	267	15	3	446	244	692	1e-48	190
rs:WP_020082018	DNA topoisomerase III [Flavobacterium sp. SCGC AAA160-P02].	30.37	438	269	13	38	454	231	653	1e-48	188
rs:WP_000766743	DNA topoisomerase III [Bacillus cereus].	31.24	429	261	11	36	448	244	654	1e-48	187
rs:WP_004276310	DNA topoisomerase III [Campylobacter upsaliensis].	29.30	454	246	11	66	455	270	712	1e-48	187
rs:WP_036873209	DNA topoisomerase III [Porphyromonas macacae].	30.86	444	274	13	18	446	213	638	1e-48	187
rs:WP_025683568	DNA topoisomerase III [Paenibacillus sp. 1-49].	31.48	413	246	10	36	439	231	615	1e-48	187
tr:A0A090WWP2_9FLAO	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.44	427	273	11	38	454	231	643	1e-48	188
rs:WP_013606785	DNA topoisomerase III [Sphaerochaeta globosa].	31.71	350	233	3	40	385	235	582	1e-48	187
rs:WP_043889999	DNA topoisomerase III [Porphyromonas gingivalis].	31.56	450	271	14	17	446	211	643	1e-48	187
rs:WP_000766744	DNA topoisomerase III [Bacillus cereus].	31.24	429	261	11	36	448	244	654	1e-48	187
rs:WP_047932116	DNA topoisomerase III [Bacillus megaterium].	31.25	400	239	7	37	435	231	595	1e-48	187
rs:WP_025907666	DNA topoisomerase III [Bacillus flexus].	32.86	353	229	5	36	385	244	591	1e-48	187
rs:WP_007574002	DNA topoisomerase III [Prevotella multisaccharivorax].	31.28	454	263	16	24	446	218	653	1e-48	187
rs:WP_016991292	DNA topoisomerase III [Flavobacterium sp. ACAM 123].	31.04	422	260	12	38	446	231	634	1e-48	187
rs:WP_045438429	DNA topoisomerase III [bacterium UASB270].	31.75	400	259	6	40	435	235	624	1e-48	187
rs:WP_044647002	DNA topoisomerase III [Paenibacillus terrae].	31.72	413	245	10	36	439	231	615	1e-48	187
tr:W0S9R8_9RHOO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.16	392	244	8	40	425	255	634	1e-48	189
rs:WP_043895884	DNA topoisomerase III [Porphyromonas gingivalis].	31.56	450	271	14	17	446	211	643	1e-48	187
rs:WP_044074329	DNA topoisomerase III [Prevotella sp. P5-60].	31.81	393	251	9	24	406	217	602	1e-48	187
tr:A0A081C7G9_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.75	400	259	6	40	435	236	625	1e-48	187
tr:F5X8C0_PORGT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:BAK24552.1};	31.56	450	271	14	17	446	226	658	1e-48	187
rs:WP_010193780	DNA topoisomerase III [Bacillus sp. m3-13].	30.45	440	271	11	36	453	244	670	1e-48	187
rs:WP_008271599	DNA topoisomerase III [Flavobacteriales bacterium ALC-1].	31.79	368	240	7	38	404	231	588	1e-48	187
rs:WP_018474722	hypothetical protein [Echinicola pacifica].	28.88	457	281	11	18	446	212	652	2e-48	187
rs:WP_004336217	DNA topoisomerase III [Thauera linaloolentis].	35.85	371	220	9	40	400	255	617	2e-48	188
rs:WP_043894242	DNA topoisomerase III [Porphyromonas gingivalis].	31.56	450	271	14	17	446	211	643	2e-48	187
rs:WP_012789015	DNA topoisomerase III [Chitinophaga pinensis].	29.89	435	262	11	47	454	240	658	2e-48	187
rs:WP_042232421	DNA topoisomerase III [Paenibacillus sp. FSL R5-0912].	31.86	408	241	10	38	435	233	613	2e-48	187
rs:WP_047130864	DNA topoisomerase III [Staphylococcus condimenti].	30.09	422	266	9	35	450	227	625	2e-48	187
rs:WP_007856134	DNA topoisomerase III, partial [Acidovorax sp. CF316].	34.43	366	221	8	47	400	269	627	2e-48	188
rs:WP_027474744	DNA topoisomerase III [Curvibacter gracilis].	33.33	366	225	8	47	400	275	633	2e-48	189
rs:WP_022357530	DNA topoisomerase III [Ruminococcus sp. CAG:379].	32.93	413	248	10	40	444	230	621	2e-48	187
rs:WP_016132735	DNA topoisomerase III [Bacillus cereus].	29.53	430	271	10	36	450	246	658	2e-48	187
rs:WP_019188572	DNA topoisomerase III [Candidatus Prevotella conceptionensis].	32.91	392	243	10	21	402	214	595	2e-48	187
tr:A0A0E2LU45_PORGN	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERJ69010.1};	31.56	450	271	14	17	446	246	678	2e-48	187
rs:WP_016249872	DNA topoisomerase III [Enterococcus casseliflavus].	31.43	420	250	11	52	455	264	661	2e-48	187
rs:WP_002170059	DNA topoisomerase III [Bacillus cereus].	30.66	437	272	12	36	454	244	667	2e-48	187
rs:WP_043894827	DNA topoisomerase III [Porphyromonas gingivalis].	31.56	450	271	14	17	446	211	643	2e-48	187
rs:WP_009890468	DNA topoisomerase III [Peptoclostridium difficile].	30.89	395	230	7	48	435	248	606	2e-48	187
rs:WP_045673653	DNA topoisomerase III [Paenibacillus beijingensis].	33.42	380	224	9	40	398	234	605	2e-48	187
rs:WP_022158033	DNA topoisomerase III [Prevotella sp. CAG:520].	32.67	404	250	11	18	406	212	608	2e-48	187
rs:WP_031228895	DNA topoisomerase III, partial [Salmonella enterica].	28.89	360	246	3	55	406	3	360	2e-48	181
rs:WP_019573873	DNA topoisomerase III [Curvibacter lanceolatus].	33.42	365	224	8	47	399	275	632	2e-48	189
tr:A0A0C7RVR1_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.40	415	244	7	20	428	226	597	2e-48	187
rs:WP_041137912	DNA topoisomerase III [Clostridiaceae bacterium GM1].	31.10	418	261	6	37	445	233	632	2e-48	187
rs:WP_043184744	DNA topoisomerase III [Burkholderia cepacia].	34.36	358	209	8	38	385	253	594	2e-48	188
rs:WP_022479411	DNA topoisomerase III [Prevotella sp. CAG:891].	33.70	365	222	9	49	402	274	629	2e-48	187
rs:WP_034298270	DNA topoisomerase III [Herbaspirillum sp. RV1423].	34.83	356	210	10	40	385	255	598	2e-48	188
rs:WP_009003768	DNA topoisomerase III [Clostridium sp. D5].	34.25	365	226	6	69	425	261	619	2e-48	187
rs:WP_000766737	DNA topoisomerase III [Bacillus cereus].	30.86	431	264	11	36	450	244	656	2e-48	187
tr:W1R7K4_PORGN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ETA26501.1};	31.56	450	271	14	17	446	226	658	2e-48	187
rs:WP_027412801	DNA topoisomerase III [Aquimarina muelleri].	29.26	417	274	8	38	446	231	634	2e-48	187
rs:WP_044397968	DNA topoisomerase III [Lacinutrix sp. Hel_I_90].	30.56	432	267	11	38	454	231	644	2e-48	187
rs:WP_035048305	DNA topoisomerase III [Anoxybacillus sp. KU2-6(11)].	30.52	439	242	11	36	459	230	620	2e-48	187
tr:A0A086F9L8_9FLAO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KFF75632.1};	32.00	425	268	10	40	459	233	641	2e-48	187
rs:WP_042210448	DNA topoisomerase III [Paenibacillus borealis].	31.86	408	241	9	38	435	233	613	2e-48	187
rs:WP_018989244	DNA topoisomerase III [Azoarcus toluclasticus].	35.23	369	223	8	40	400	255	615	2e-48	188
rs:WP_009433703	DNA topoisomerase III [Porphyromonas sp. oral taxon 279].	33.57	423	254	14	38	446	237	646	2e-48	187
gpu:CP009928_37	DNA topoisomerase III [Chryseobacterium gallinarum]	32.00	425	268	10	40	459	233	641	2e-48	187
rs:WP_022429476	DNA topoisomerase III [Prevotella stercorea CAG:629].	32.26	403	252	10	18	406	212	607	2e-48	187
rs:WP_045470857	DNA topoisomerase III [Burkholderiales bacterium GJ-E10].	33.11	441	220	13	30	426	247	656	2e-48	188
rs:WP_042985232	DNA topoisomerase III [Bacillus mycoides].	30.66	437	272	12	36	454	244	667	2e-48	187
rs:WP_026703297	DNA topoisomerase III [Bacillus aidingensis].	29.89	358	238	5	38	391	236	584	2e-48	187
rs:WP_046226540	DNA topoisomerase III [Paenibacillus dauci].	33.16	389	234	9	40	408	234	616	2e-48	187
rs:WP_013083050	DNA topoisomerase III [Bacillus megaterium].	30.94	404	235	7	37	435	231	595	2e-48	187
rs:WP_015734703	DNA topoisomerase III [Paenibacillus sp. Y412MC10].	31.14	395	241	10	40	411	234	620	2e-48	187
rs:WP_009904388	DNA topoisomerase III [Peptoclostridium difficile].	30.89	395	230	7	48	435	248	606	2e-48	186
rs:WP_000766763	DNA topoisomerase III [Bacillus cereus].	30.84	428	264	10	36	448	244	654	2e-48	187
rs:WP_036867434	DNA topoisomerase III [Porphyromonas canoris].	29.07	430	288	10	22	446	218	635	2e-48	186
tr:A0A068N6R0_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.70	430	266	10	36	450	173	585	2e-48	186
rs:WP_039367564	DNA topoisomerase III [Chryseobacterium taiwanense].	32.17	429	262	11	40	449	233	651	2e-48	187
rs:WP_048502025	DNA topoisomerase III [Chryseobacterium sp. BLS98].	32.21	416	268	8	40	453	233	636	2e-48	187
rs:WP_033922359	topoisomerase I [Enterococcus faecalis].	31.60	462	262	17	24	454	233	671	2e-48	187
tr:A0A073ICB2_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KEJ87404.1};	32.25	369	235	9	37	401	102	459	2e-48	185
rs:WP_036685684	DNA topoisomerase III [Paenibacillus sp. MSt1].	34.29	347	198	7	70	391	261	602	2e-48	187
rs:WP_016114467	DNA topoisomerase III [Bacillus cereus].	29.67	428	269	10	36	448	245	655	2e-48	187
rs:WP_036665367	DNA topoisomerase III [Paenibacillus sp. FSL H8-457].	31.14	395	241	10	40	411	234	620	2e-48	187
rs:WP_016412253	DNA topoisomerase III [Prevotella sp. CAG:1031].	34.46	354	222	8	37	387	230	576	2e-48	186
rs:WP_029440902	DNA topoisomerase III [Bacillus thuringiensis].	31.09	431	263	11	36	450	244	656	2e-48	187
rs:WP_016612333	DNA topoisomerase [Enterococcus faecium].	31.19	420	251	11	52	455	264	661	2e-48	187
rs:WP_003188538	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	29.77	430	270	10	36	450	244	656	2e-48	187
rs:WP_025081433	DNA topoisomerase III [Porphyromonas bennonis].	33.24	373	237	9	18	386	214	578	2e-48	186
rs:WP_041224587	DNA topoisomerase III, partial [Dechloromonas aromatica].	33.25	421	229	13	40	426	255	657	2e-48	187
tr:Q47K54_DECAR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.25	421	229	13	40	426	264	666	2e-48	187
tr:A0A0C7I9V3_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.40	415	244	7	20	428	226	597	2e-48	186
rs:WP_033674734	DNA topoisomerase III [Bacillus gaemokensis].	32.86	353	224	6	36	385	244	586	2e-48	186
rs:WP_020979454	DNA topoisomerase III [Burkholderia cenocepacia].	34.64	358	208	8	38	385	253	594	3e-48	187
rs:WP_000766739	DNA topoisomerase III [Bacillus thuringiensis].	30.86	431	264	11	36	450	244	656	3e-48	186
rs:WP_000217286	DNA topoisomerase III [Bacillus cereus].	30.86	431	264	12	36	450	245	657	3e-48	186
rs:WP_033827051	DNA topoisomerase III [Bacillus sp. KW-12].	29.51	427	266	8	36	459	230	624	3e-48	186
tr:A0A0C7LFG7_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.40	415	244	7	20	428	226	597	3e-48	186
rs:WP_013056933	DNA topoisomerase III [Bacillus megaterium].	31.00	400	240	7	37	435	231	595	3e-48	186
rs:WP_021130050	DNA topoisomerase III family protein [[Clostridium] sordellii].	29.40	415	244	7	20	428	226	597	3e-48	186
rs:WP_035509775	DNA topoisomerase III [Burkholderia jiangsuensis].	32.87	359	213	8	38	385	253	594	3e-48	187
rs:WP_021338404	DNA topoisomerase III [Staphylococcus equorum].	30.12	415	261	9	43	450	235	627	3e-48	186
rs:WP_041397274	DNA topoisomerase III [Polynucleobacter necessarius].	31.58	437	247	12	38	439	248	667	3e-48	187
rs:WP_019427399	DNA topoisomerase III [Limnohabitans sp. Rim28].	32.82	393	242	9	45	425	266	648	3e-48	188
rs:WP_043352648	DNA topoisomerase III [Bacillus cereus].	30.86	431	264	11	36	450	245	657	3e-48	186
rs:WP_034697604	DNA topoisomerase III [Chryseobacterium sp. CF365].	32.25	431	260	11	40	449	233	652	3e-48	186
rs:WP_026435498	DNA topoisomerase III [Acidovorax sp. JHL-9].	34.54	359	216	8	54	400	276	627	3e-48	188
rs:WP_026350873	DNA topoisomerase III [Dyadobacter beijingensis].	32.74	452	239	16	40	454	233	656	3e-48	186
rs:WP_047378222	DNA topoisomerase III [Chryseobacterium sp. YR459].	32.25	431	260	11	40	449	233	652	3e-48	186
tr:A0A0C7J747_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.40	415	244	7	20	428	226	597	3e-48	186
rs:WP_002687992	DNA topoisomerase III [Bergeyella zoohelcum].	31.67	420	254	12	54	454	247	652	3e-48	186
rs:WP_000766754	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	31.00	429	262	11	36	448	244	654	3e-48	186
rs:WP_006208277	DNA topoisomerase III [Paenibacillus vortex].	32.11	408	240	8	38	435	233	613	3e-48	186
rs:WP_005866302	MULTISPECIES: DNA topoisomerase III [Parabacteroides].	32.25	369	235	9	37	401	230	587	3e-48	186
tr:S3IA68_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.00	429	262	12	36	448	248	658	3e-48	186
rs:WP_025752281	DNA topoisomerase III [Bacillus flexus].	31.00	400	240	7	37	435	231	595	3e-48	186
rs:WP_000766766	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	31.00	429	262	11	36	448	244	654	3e-48	186
rs:WP_002012275	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	29.77	430	270	10	36	450	244	656	3e-48	186
rs:WP_002118313	DNA topoisomerase III [Bacillus cereus].	29.77	430	270	10	36	450	244	656	3e-48	186
rs:WP_000766758	DNA topoisomerase III [Bacillus cereus].	29.77	430	270	11	36	450	244	656	3e-48	186
tr:B1XSN4_POLNS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.58	437	247	12	38	439	271	690	3e-48	187
rs:WP_002192122	DNA topoisomerase III [Bacillus cereus].	30.66	437	272	12	36	454	244	667	3e-48	186
rs:WP_000766770	DNA topoisomerase III [Bacillus cereus].	31.86	430	257	11	36	448	244	654	3e-48	186
rs:WP_000766740	DNA topoisomerase III [Bacillus thuringiensis].	31.00	429	262	12	36	448	244	654	3e-48	186
rs:WP_028408630	DNA topoisomerase III [Bacillus sp. 171095_106].	31.00	400	240	7	37	435	231	595	3e-48	186
rs:WP_043812033	DNA topoisomerase III, partial [Desulfomicrobium baculatum].	33.04	342	211	6	50	385	253	582	3e-48	185
rs:WP_018361007	DNA topoisomerase III [Porphyromonas macacae].	30.93	443	275	13	18	446	213	638	3e-48	186
rs:WP_000766757	DNA topoisomerase III [Bacillus cereus].	29.77	430	270	11	36	450	244	656	3e-48	186
rs:WP_042362257	DNA topoisomerase III [Staphylococcus xylosus].	30.17	411	266	7	43	450	235	627	3e-48	186
rs:WP_046525659	DNA topoisomerase III [Bacillus sp. SA2-6].	30.54	429	254	9	36	457	230	621	3e-48	186
rs:WP_040744842	DNA topoisomerase III, partial [alpha proteobacterium BAL199].	34.17	360	214	10	38	381	228	580	3e-48	185
rs:WP_000766784	DNA topoisomerase III [Bacillus cereus].	31.00	429	262	11	36	448	244	654	3e-48	186
rs:WP_000766755	DNA topoisomerase III [Bacillus cereus].	31.00	429	262	11	36	448	244	654	3e-48	186
rs:WP_000766771	MULTISPECIES: DNA topoisomerase III [Bacillus].	31.00	429	262	11	36	448	244	654	3e-48	186
rs:WP_014190097	DNA topoisomerase III [Burkholderia sp. YI23].	33.15	359	212	8	38	385	253	594	3e-48	187
rs:WP_042133389	DNA topoisomerase III [Paenibacillus sp. FSL P4-0081].	31.70	407	243	9	38	435	233	613	3e-48	186
rs:WP_045244221	DNA topoisomerase III [Paenibacillus polymyxa].	31.25	400	240	8	36	426	231	604	3e-48	186
rs:WP_029321603	DNA topoisomerase III [Bacillus sp. RP1137].	31.00	400	240	7	37	435	231	595	3e-48	186
rs:WP_002056427	DNA topoisomerase III [Bacillus cereus].	32.58	353	225	6	36	385	245	587	3e-48	186
rs:WP_038496368	DNA topoisomerase III [Janthinobacterium agaricidamnosum].	32.33	399	244	11	40	426	255	639	3e-48	187
tr:A8TU58_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	32.49	397	241	11	38	414	228	617	3e-48	186
rs:WP_000766738	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.86	431	264	11	36	450	244	656	4e-48	186
rs:WP_000766735	DNA topoisomerase III [Bacillus cereus].	30.86	431	264	12	36	450	244	656	4e-48	186
rs:WP_019937515	DNA topoisomerase III [Bordetella sp. FB-8].	35.26	363	204	10	38	385	253	599	4e-48	187
rs:WP_021408466	DNA topoisomerase III family protein [Peptoclostridium difficile].	30.89	395	230	7	48	435	248	606	4e-48	186
rs:WP_021385145	DNA topoisomerase III family protein [Peptoclostridium difficile].	30.53	393	234	6	48	435	248	606	4e-48	186
rs:WP_039310314	DNA topoisomerase III [Paenibacillus sp. IHB B 3415].	31.70	407	243	9	38	435	233	613	4e-48	186
tr:J3HUJ6_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.24	346	214	7	50	385	1	339	4e-48	185
rs:WP_000766782	DNA topoisomerase III [Bacillus thuringiensis].	30.86	431	264	11	36	450	244	656	4e-48	186
rs:WP_000766781	DNA topoisomerase III [Bacillus cereus].	30.77	429	263	11	36	448	244	654	4e-48	186
tr:A0A0C7RH49_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.37	412	242	7	20	425	226	594	4e-48	186
rs:WP_023842835	DNA topoisomerase [Burkholderia sp. M701].	32.85	411	242	8	36	429	266	659	4e-48	187
rs:WP_002086236	DNA topoisomerase III [Bacillus cereus].	29.77	430	270	10	36	450	244	656	4e-48	186
rs:NP_844316	DNA topoisomerase III [Bacillus anthracis str. Ames].	30.86	431	264	11	36	450	244	656	4e-48	186
rs:WP_000766783	DNA topoisomerase III [Bacillus cereus].	30.86	431	264	11	36	450	244	656	4e-48	186
rs:WP_022112818	DNA topoisomerase [Roseburia intestinalis CAG:13].	30.07	439	273	11	47	459	276	706	4e-48	189
rs:WP_000766752	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.84	428	264	10	36	448	244	654	4e-48	186
rs:WP_001991674	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.86	431	264	12	36	450	244	656	4e-48	186
rs:WP_021426535	DNA topoisomerase III family protein [Peptoclostridium difficile].	30.89	395	230	7	48	435	248	606	4e-48	186
rs:WP_000766764	DNA topoisomerase III [Bacillus cereus].	30.77	429	263	11	36	448	244	654	4e-48	186
rs:WP_022383850	DNA topoisomerase III [Bacteroides sp. CAG:462].	29.93	441	263	11	41	446	267	696	4e-48	186
rs:WP_044584352	DNA topoisomerase III [Bacillus bombysepticus].	30.77	429	263	11	36	448	244	654	4e-48	186
rs:WP_046959122	DNA topoisomerase III [Bacillus cereus].	29.77	430	270	10	36	450	244	656	4e-48	186
rs:WP_005875378	DNA topoisomerase III [Porphyromonas gingivalis].	31.33	450	272	14	17	446	211	643	4e-48	186
rs:WP_017812425	hypothetical protein [Paenibacillus sp. A9].	33.16	389	234	10	40	408	234	616	4e-48	186
rs:WP_044742475	DNA topoisomerase III [Anoxybacillus sp. ATCC BAA-2555].	30.52	403	245	6	36	435	230	600	4e-48	186
rs:WP_027815887	DNA topoisomerase III [Burkholderia bannensis].	34.54	359	207	9	38	385	253	594	4e-48	187
rs:WP_009274928	MULTISPECIES: DNA topoisomerase III [Parabacteroides].	32.25	369	235	9	37	401	230	587	4e-48	186
rs:WP_036661964	DNA topoisomerase III [Paenibacillus sp. FSL H8-457].	31.78	409	241	8	38	435	233	614	4e-48	186
rs:WP_044544965	DNA topoisomerase III [Parabacteroides distasonis].	32.25	369	235	9	37	401	230	587	4e-48	186
rs:WP_009316961	DNA topoisomerase III [Tannerella sp. 6_1_58FAA_CT1].	31.37	373	242	9	37	405	230	592	4e-48	186
rs:WP_044632471	DNA topoisomerase III [Tamlana sedimentorum].	32.52	369	234	8	18	385	212	566	4e-48	186
rs:WP_036559719	DNA topoisomerase III [Oligella urethralis].	34.15	366	204	10	38	385	253	599	4e-48	187
tr:D7IPC2_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFI09260.1};	32.25	369	235	9	37	401	220	577	4e-48	186
rs:WP_042184736	DNA topoisomerase III [Paenibacillus sp. FSL H7-0737].	30.96	407	249	8	36	435	231	612	5e-48	186
rs:WP_000766769	DNA topoisomerase III [Bacillus cereus].	30.77	429	263	11	36	448	244	654	5e-48	186
rs:WP_025371025	DNA topoisomerase III [Advenella mimigardefordensis].	33.61	363	210	7	38	385	253	599	5e-48	187
rs:WP_044039668	DNA topoisomerase III [Clostridium bornimense].	31.04	393	249	6	48	435	244	619	5e-48	186
rs:WP_000766734	MULTISPECIES: DNA topoisomerase III [Bacillus].	30.77	429	263	11	36	448	244	654	5e-48	186
rs:WP_044013192	DNA topoisomerase III [Hymenobacter sp. APR13].	32.89	377	237	8	30	396	245	615	5e-48	186
rs:WP_011979365	DNA topoisomerase III [Janthinobacterium sp. Marseille].	34.27	356	213	8	40	385	255	599	5e-48	187
rs:WP_047097004	DNA topoisomerase III [Chryseobacterium indologenes].	35.45	347	217	7	40	384	233	574	5e-48	186
rs:WP_047486591	DNA topoisomerase III [Chryseobacterium sp. OV705].	32.02	431	261	11	40	449	233	652	5e-48	186
rs:WP_008774235	DNA topoisomerase III [Bacteroides sp. 2_1_33B].	32.25	369	235	9	37	401	230	587	5e-48	186
tr:C7X8X1_9PORP	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEU51650.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EEU51650.1};	32.25	369	235	9	37	401	241	598	5e-48	186
rs:WP_012819086	DNA topoisomerase III [Paenibacillus sp. Y412MC10].	31.48	413	237	8	38	435	233	614	5e-48	186
rs:WP_035127158	DNA topoisomerase III, partial [Conexibacter woesei].	30.92	401	257	9	56	449	270	657	5e-48	186
tr:A6LCM5_PARD8	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:ABR43439.1};	32.25	369	235	9	37	401	231	588	5e-48	186
rs:WP_027702332	DNA topoisomerase III [[Clostridium] mangenotii].	29.25	400	240	6	43	435	243	606	5e-48	186
rs:WP_028541705	DNA topoisomerase III [Paenibacillus sp. UNCCL52].	33.60	372	219	9	40	391	234	597	5e-48	186
rs:WP_036074259	DNA topoisomerase III [Listeria aquatica].	32.97	364	226	5	38	396	231	581	5e-48	186
rs:WP_021362717	DNA topoisomerase III family protein [Peptoclostridium difficile].	31.14	395	229	7	48	435	248	606	5e-48	186
rs:WP_000540560	DNA topoisomerase III [Bacillus thuringiensis].	30.63	431	265	12	36	450	246	658	5e-48	186
rs:WP_034527038	MULTISPECIES: DNA topoisomerase III [Bacteroidales].	32.25	369	235	9	37	401	230	587	5e-48	186
rs:WP_036610710	MULTISPECIES: DNA topoisomerase III [Parabacteroides].	32.25	369	235	9	37	401	230	587	5e-48	186
rs:WP_012779890	DNA topoisomerase III [Dyadobacter fermentans].	32.44	447	246	15	40	454	233	655	5e-48	186
tr:A0A0C7SIK7_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.40	415	244	7	20	428	226	597	5e-48	186
rs:WP_005858139	DNA topoisomerase III [Parabacteroides distasonis].	32.25	369	235	9	37	401	230	587	5e-48	186
rs:WP_047388076	DNA topoisomerase III [Chryseobacterium sp. YR485].	32.02	431	261	11	40	449	233	652	5e-48	186
rs:WP_027376452	DNA topoisomerase III [Chryseobacterium palustre].	31.85	427	262	12	40	449	233	647	5e-48	186
rs:WP_022191868	hypothetical protein [Parabacteroides sp. CAG:2].	32.25	369	235	9	37	401	230	587	5e-48	186
rs:WP_014257080	DNA topoisomerase [[Clostridium] clariflavum].	33.68	380	228	11	38	401	269	640	5e-48	185
rs:WP_046947023	DNA topoisomerase III [Bacillus cereus].	30.84	428	264	10	36	448	244	654	5e-48	186
rs:WP_013337716	DNA topoisomerase III [Burkholderia sp. CCGE1003].	35.38	359	204	9	38	385	253	594	5e-48	187
rs:WP_021364630	DNA topoisomerase III family protein [Peptoclostridium difficile].	30.89	395	230	7	48	435	248	606	6e-48	185
tr:G4M7R3_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.15	359	212	8	38	385	253	594	6e-48	186
rs:WP_007881181	DNA topoisomerase III [Herbaspirillum sp. CF444].	34.55	356	211	10	40	385	255	598	6e-48	186
rs:WP_017690704	DNA topoisomerase III [Paenibacillus sp. PAMC 26794].	32.20	410	243	9	38	439	233	615	6e-48	185
rs:WP_043982332	DNA topoisomerase III [Bacillus aryabhattai].	31.00	400	240	7	37	435	231	595	6e-48	185
rs:WP_006094529	MULTISPECIES: DNA topoisomerase III [Bacillus].	32.49	354	224	6	36	385	244	586	6e-48	185
rs:WP_022391175	DNA topoisomerase III [Tannerella sp. CAG:51].	31.37	373	242	9	37	405	230	592	6e-48	185
rs:WP_009592313	DNA topoisomerase III [Paenibacillus sp. HGF5].	31.48	413	237	8	38	435	233	614	6e-48	185
rs:WP_022149832	DNA topoisomerase III [Prevotella sp. CAG:1320].	30.33	399	255	9	24	406	217	608	6e-48	186
rs:WP_034749282	DNA topoisomerase III [Janthinobacterium lividum].	33.33	357	217	8	40	385	255	601	6e-48	186
rs:WP_000766741	DNA topoisomerase III [Bacillus thuringiensis].	30.84	428	264	10	36	448	244	654	6e-48	185
rs:WP_040501928	DNA topoisomerase III, partial [Herbaspirillum sp. YR522].	33.24	346	214	7	50	385	1	339	6e-48	185
rs:WP_003196873	MULTISPECIES: DNA topoisomerase III [Bacillus].	32.77	354	223	6	36	385	244	586	6e-48	185
rs:WP_022600591	DNA topoisomerase III [Coprobacter fastidiosus].	31.37	373	242	9	37	405	230	592	6e-48	185
rs:WP_000766732	DNA topoisomerase III [Bacillus thuringiensis].	30.84	428	264	10	36	448	244	654	6e-48	185
rs:WP_009229127	DNA topoisomerase III [Prevotella sp. oral taxon 317].	32.31	390	249	9	21	402	214	596	7e-48	185
rs:WP_028282183	DNA topoisomerase III [Olleya marilimosa].	32.08	371	231	8	38	404	231	584	7e-48	186
rs:WP_039271318	DNA topoisomerase III [Paenibacillus polymyxa].	33.33	372	220	9	40	391	234	597	7e-48	186
rs:WP_008917977	DNA topoisomerase III [Burkholderia sp. H160].	34.92	358	207	9	38	385	253	594	7e-48	186
rs:WP_007902515	DNA topoisomerase III [Prevotella stercorea].	32.27	409	250	11	18	406	212	613	7e-48	185
rs:WP_023966311	DNA topoisomerase III [Paenibacillus sp. JCM 10914].	32.68	410	237	8	38	435	233	615	7e-48	185
rs:WP_036640886	DNA topoisomerase III [Paenibacillus sp. FSL R5-808].	32.11	408	240	8	38	435	233	613	7e-48	185
rs:WP_009616856	DNA topoisomerase III [Desulfosporosinus sp. OT].	33.51	370	224	7	40	392	255	619	7e-48	186
tr:A0A098ETD9_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.67	401	240	6	36	434	233	601	7e-48	185
tr:A8TWU8_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	32.49	397	241	11	38	414	228	617	7e-48	186
rs:WP_041753934	DNA topoisomerase III [Burkholderia rhizoxinica].	35.29	340	196	8	55	385	270	594	7e-48	186
rs:WP_021421634	DNA topoisomerase III family protein [Peptoclostridium difficile].	31.14	395	229	7	48	435	248	606	7e-48	185
rs:WP_035824548	DNA topoisomerase III [Janthinobacterium sp. RA13].	33.33	357	217	8	40	385	255	601	7e-48	186
rs:WP_025708278	DNA topoisomerase III [Paenibacillus graminis].	31.36	405	247	8	38	435	233	613	8e-48	185
rs:WP_046683462	DNA topoisomerase III [Janthinobacterium sp. KBS0711].	33.33	357	217	8	40	385	255	601	8e-48	186
rs:WP_044927340	DNA topoisomerase, partial [Roseburia inulinivorans].	33.15	368	217	9	47	392	263	623	8e-48	184
rs:WP_034784739	DNA topoisomerase III [Janthinobacterium lividum].	33.33	357	217	8	40	385	255	601	8e-48	186
rs:WP_018026660	hypothetical protein [Oligella urethralis].	34.15	366	204	10	38	385	253	599	8e-48	186
rs:WP_006858739	DNA topoisomerase [Roseburia intestinalis].	29.61	439	275	11	47	459	276	706	8e-48	188
rs:WP_042161815	DNA topoisomerase III [Paenibacillus sp. G1].	34.29	385	226	9	31	391	220	601	8e-48	185
rs:WP_025598065	DNA topoisomerase III [Burkholderia sp. WSM2230].	35.38	359	204	9	38	385	253	594	8e-48	186
rs:WP_009667728	DNA topoisomerase III [Oxalobacteraceae bacterium IMCC9480].	34.83	356	211	9	40	385	255	599	8e-48	186
rs:WP_042536416	DNA topoisomerase III [Anoxybacillus ayderensis].	30.54	406	237	7	36	435	230	596	8e-48	185
rs:WP_021026750	DNA topoisomerase III [Comamonas sp. B-9].	34.79	365	219	9	47	399	270	627	9e-48	187
rs:WP_013871149	DNA topoisomerase III [Lacinutrix sp. 5H-3-7-4].	29.79	433	269	11	38	454	231	644	9e-48	185
rs:WP_014098418	DNA topoisomerase III [Bacillus coagulans].	31.33	450	271	13	18	446	222	654	9e-48	185
rs:WP_046720776	DNA topoisomerase III [Bacillus coagulans].	31.33	450	271	13	18	446	222	654	9e-48	185
rs:WP_012431376	DNA topoisomerase III [Burkholderia phytofirmans].	35.65	359	203	9	38	385	253	594	9e-48	186
rs:WP_046213924	DNA topoisomerase III [Paenibacillus wulumuqiensis].	31.31	412	250	6	34	435	229	617	9e-48	185
rs:WP_035047422	DNA topoisomerase III [Anoxybacillus sp. KU2-6(11)].	30.39	431	270	10	36	453	244	657	9e-48	185
rs:WP_039811820	DNA topoisomerase III [Jeotgalibacillus sp. D5].	33.24	358	223	5	43	396	238	583	9e-48	185
rs:WP_021620679	DNA topoisomerase [Aneurinibacillus aneurinilyticus].	31.97	441	258	13	36	453	244	665	9e-48	185
rs:WP_010531156	DNA topoisomerase III [Lentibacillus jeotgali].	32.67	404	249	12	59	454	269	657	1e-47	185
rs:WP_018914713	DNA topoisomerase III [Thiomonas sp. FB-6].	33.52	355	211	7	41	385	259	598	1e-47	186
rs:WP_023263469	DNA topoisomerase III [Cupriavidus sp. HPC(L)].	34.54	359	208	9	38	385	253	595	1e-47	186
rs:WP_033466984	DNA topoisomerase III [Bordetella bronchiseptica].	34.16	363	208	9	38	385	252	598	1e-47	186
rs:WP_043199706	DNA topoisomerase III [Bradyrhizobium sp. URHA0002].	32.10	377	225	10	38	392	229	596	1e-47	185
rs:WP_000766742	DNA topoisomerase III [Bacillus cereus].	33.90	354	219	7	36	385	244	586	1e-47	185
rs:WP_034686218	DNA topoisomerase III [Chryseobacterium piperi].	34.48	348	219	8	40	384	233	574	1e-47	185
rs:WP_035188903	DNA topoisomerase III [Bacillus coagulans].	31.33	450	271	13	18	446	222	654	1e-47	185
rs:WP_022506815	DNA topoisomerase III [Bacteroides sp. CAG:98].	31.69	366	232	8	41	396	282	639	1e-47	185
tr:E5AND1_BURRH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	35.29	340	196	8	55	385	291	615	1e-47	186
rs:WP_027213817	DNA topoisomerase III [Burkholderia sp. WSM2232].	35.10	359	205	9	38	385	253	594	1e-47	186
rs:WP_041122970	DNA topoisomerase III [Jeotgalibacillus alimentarius].	31.03	406	251	12	59	456	268	652	1e-47	184
rs:WP_005644013	DNA topoisomerase III [Parabacteroides merdae].	31.34	367	241	8	37	401	230	587	1e-47	184
rs:WP_022242126	DNA topoisomerase [Clostridium sp. CAG:413].	33.74	406	234	13	47	446	268	644	1e-47	185
rs:WP_038952236	DNA topoisomerase III, partial [Bradyrhizobium japonicum].	32.53	375	222	10	40	392	230	595	1e-47	184
rs:WP_034446774	DNA topoisomerase [Butyrivibrio sp. AE2032].	30.91	440	254	12	47	446	270	699	1e-47	187
rs:WP_011869699	DNA topoisomerase III [Herminiimonas arsenicoxydans].	33.89	357	214	9	40	385	255	600	1e-47	186
rs:WP_021402614	DNA topoisomerase III family protein [Peptoclostridium difficile].	30.89	395	230	7	48	435	248	606	1e-47	184
rs:WP_014460219	DNA topoisomerase III [Bacillus megaterium].	31.00	400	240	8	37	435	231	595	1e-47	184
rs:WP_013520941	DNA topoisomerase III [Alicycliphilus denitrificans].	33.61	366	224	8	47	400	270	628	1e-47	187
rs:WP_047433757	DNA topoisomerase III [Chryseobacterium sp. YR477].	32.02	431	261	11	40	449	233	652	1e-47	184
rs:WP_028608020	DNA topoisomerase III [Olleya sp. VCSM12].	31.79	368	236	8	38	404	231	584	1e-47	185
tr:U6RS94_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOA58661.1};	31.69	366	232	8	41	396	282	639	1e-47	185
rs:WP_006044967	DNA topoisomerase III [Prevotella pallens].	35.63	334	192	11	79	398	274	598	1e-47	184
rs:WP_018451999	DNA topoisomerase III [Bacteroides massiliensis].	31.69	366	232	8	41	396	264	621	1e-47	184
rs:WP_007428825	DNA topoisomerase III [Paenibacillus sp. Aloe-11].	30.27	413	252	9	36	439	231	616	1e-47	184
rs:WP_014224886	DNA topoisomerase III [Tannerella forsythia].	33.42	365	229	9	37	396	230	585	1e-47	184
rs:WP_043895468	DNA topoisomerase III [Porphyromonas gingivalis].	31.33	450	272	14	17	446	211	643	1e-47	184
rs:WP_029517449	DNA topoisomerase III [Paenibacillus polymyxa].	33.33	372	220	9	40	391	234	597	1e-47	185
tr:U2LGV2_PORGN	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERJ88694.1};	31.33	450	272	14	17	446	226	658	1e-47	184
rs:WP_020229248	DNA topoisomerase III [Acidovorax sp. MR-S7].	33.42	380	231	9	36	400	255	627	1e-47	186
rs:WP_025604343	DNA topoisomerase III [Pontibacter actiniarum].	30.22	460	278	12	18	443	213	663	1e-47	185
rs:WP_028102328	DNA topoisomerase III [Pseudoduganella violaceinigra].	33.43	356	217	8	40	385	255	600	1e-47	186
rs:WP_005231974	DNA topoisomerase [Enterococcus casseliflavus].	30.95	420	252	11	52	455	264	661	1e-47	184
rs:WP_024998619	DNA topoisomerase III [Prevotella falsenii].	31.97	391	245	11	18	397	217	597	1e-47	184
rs:WP_004437152	DNA topoisomerase III [Bacillus methanolicus].	32.20	354	230	6	36	385	244	591	1e-47	184
rs:WP_025719153	DNA topoisomerase III [Paenibacillus sp. 1-18].	30.92	414	248	10	36	439	231	616	1e-47	184
rs:WP_026683476	DNA topoisomerase III [Bacillus coagulans].	31.33	450	271	13	18	446	222	654	1e-47	184
rs:WP_010393247	DNA topoisomerase III [Janthinobacterium lividum].	31.14	411	262	8	40	439	255	655	1e-47	186
rs:WP_025844504	DNA topoisomerase III, partial [Paenibacillus ehimensis].	33.72	347	200	7	70	391	261	602	1e-47	184
rs:WP_035386680	DNA topoisomerase III, partial [Exiguobacterium sp. S17].	32.78	424	245	12	47	452	255	656	1e-47	184
rs:WP_017434187	DNA topoisomerase III [Geobacillus caldoxylosilyticus].	30.23	430	268	12	36	450	245	657	1e-47	184
rs:WP_021993625	DNA topoisomerase III [Prevotella sp. CAG:487].	30.44	473	270	14	18	446	212	669	1e-47	184
rs:WP_046826025	DNA topoisomerase III [Tannerella forsythia].	33.42	365	229	9	37	396	230	585	1e-47	184
rs:WP_034374893	DNA topoisomerase III [Comamonas testosteroni].	33.87	372	227	8	40	399	263	627	1e-47	186
rs:WP_000766756	DNA topoisomerase III [Bacillus cereus].	30.77	429	263	11	36	448	244	654	1e-47	184
rs:WP_026954375	DNA topoisomerase III [Algoriphagus vanfongensis].	30.18	444	278	12	18	448	212	636	1e-47	184
rs:WP_042969683	DNA topoisomerase III [Bacillus thuringiensis].	30.77	429	263	11	36	448	244	654	1e-47	184
rs:WP_003397193	DNA topoisomerase III [Anoxybacillus flavithermus].	30.07	439	244	11	36	459	230	620	1e-47	184
tr:A0A0E4BDZ8_TANFO	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:BAR48926.1};	33.42	365	229	9	37	396	230	585	1e-47	184
rs:WP_021366949	DNA topoisomerase III family protein [Peptoclostridium difficile].	31.14	395	229	7	48	435	248	606	1e-47	184
rs:WP_018949090	DNA topoisomerase III [Thioalkalivibrio sp. ALMg11].	33.78	376	229	7	38	408	246	606	1e-47	184
rs:WP_024633551	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	32.05	415	245	10	33	439	230	615	1e-47	184
rs:WP_010802584	MULTISPECIES: DNA topoisomerase III [Parabacteroides].	31.37	373	241	9	37	405	230	591	1e-47	184
tr:A0A0E9LJN9_9BURK	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAO25498.1};	33.61	366	224	8	47	400	270	628	1e-47	186
rs:WP_035482038	DNA topoisomerase III [Burkholderia phenoliruptrix].	34.36	358	209	9	38	385	253	594	1e-47	186
rs:WP_028357446	DNA topoisomerase III [Brackiella oedipodis].	33.43	362	223	6	38	385	253	610	1e-47	186
rs:WP_039272353	DNA topoisomerase III [Paenibacillus polymyxa].	31.67	401	237	9	36	426	231	604	2e-47	184
rs:WP_038810916	DNA topoisomerase III, partial [Peptoclostridium difficile].	30.53	393	234	6	48	435	248	606	2e-47	184
rs:WP_046147493	DNA topoisomerase III [Parabacteroides goldsteinii].	31.37	373	241	9	37	405	230	591	2e-47	184
rs:WP_015001367	DNA topoisomerase III [Burkholderia phenoliruptrix].	34.36	358	209	9	38	385	253	594	2e-47	186
rs:WP_007658541	DNA topoisomerase III [Parabacteroides goldsteinii].	31.37	373	241	9	37	405	230	591	2e-47	184
rs:WP_034122848	DNA topoisomerase III, partial [Peptococcaceae bacterium BICA1-7].	33.78	373	228	9	59	428	256	612	2e-47	184
rs:WP_005638697	DNA topoisomerase III [Parabacteroides merdae].	31.34	367	241	8	37	401	230	587	2e-47	184
rs:WP_028362087	DNA topoisomerase III [Burkholderia sp. JPY366].	34.36	358	209	9	38	385	253	594	2e-47	185
rs:WP_000766767	DNA topoisomerase III [Bacillus thuringiensis].	30.61	428	265	10	36	448	244	654	2e-47	184
rs:WP_022618510	DNA topoisomerase III [Peptoclostridium difficile].	30.89	395	230	7	48	435	248	606	2e-47	184
rs:WP_043935007	MULTISPECIES: DNA topoisomerase III [Bacillus].	30.77	429	263	12	36	448	244	654	2e-47	184
rs:WP_013586805	DNA topoisomerase III [Burkholderia sp. CCGE1001].	34.36	358	209	9	38	385	253	594	2e-47	185
rs:WP_021398054	DNA topoisomerase III family protein [Peptoclostridium difficile].	31.14	395	229	7	48	435	248	606	2e-47	184
rs:WP_029527029	DNA topoisomerase III [Polaromonas glacialis].	33.17	398	239	11	47	430	275	659	2e-47	186
rs:WP_031883559	DNA topoisomerase III, partial [Staphylococcus aureus].	29.01	424	269	9	35	450	31	430	2e-47	181
rs:WP_025364046	DNA topoisomerase III [Paenibacillus polymyxa].	30.75	400	242	8	36	426	231	604	2e-47	184
rs:WP_013310504	DNA topoisomerase III [Paenibacillus polymyxa].	33.87	372	218	9	40	391	234	597	2e-47	184
rs:WP_034023840	hypothetical protein [Pseudomonas aeruginosa].	31.09	431	272	13	38	452	240	661	2e-47	184
rs:WP_022484510	DNA topoisomerase [Clostridium sp. CAG:389].	31.81	393	234	12	31	398	262	645	2e-47	184
rs:WP_028513383	DNA topoisomerase III [Ruminococcaceae bacterium AE2021].	32.45	413	254	10	40	445	228	622	2e-47	184
rs:WP_007132739	DNA topoisomerase III [Paenibacillus lactis].	33.17	413	230	11	38	435	233	614	2e-47	184
rs:WP_005797214	DNA topoisomerase III [Acidovorax delafieldii].	33.98	359	218	8	54	400	276	627	2e-47	186
rs:WP_022412826	DNA topoisomerase [Clostridium sp. CAG:470].	31.34	402	233	12	31	398	262	654	2e-47	184
gp:HE577055_73	DNA topoisomerase III [Paenibacillus polymyxa M1]	32.84	341	220	7	50	385	260	596	2e-47	187
rs:WP_000766773	DNA topoisomerase III [Bacillus cereus].	30.63	431	265	11	36	450	244	656	2e-47	184
rs:WP_021370480	DNA topoisomerase III family protein [Peptoclostridium difficile].	30.89	395	230	7	48	435	248	606	2e-47	184
rs:WP_017426164	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	31.00	400	241	8	36	426	231	604	2e-47	184
rs:WP_021359429	DNA topoisomerase III family protein [Peptoclostridium difficile].	30.38	395	232	6	48	435	248	606	2e-47	184
rs:WP_022100017	DNA topoisomerase [Proteobacteria bacterium CAG:139].	33.92	398	232	12	40	425	254	632	2e-47	185
rs:WP_021390633	DNA topoisomerase III family protein [Peptoclostridium difficile].	30.89	395	230	7	48	435	248	606	2e-47	184
rs:WP_033452845	DNA topoisomerase III [Bordetella bronchiseptica].	34.16	363	208	9	38	385	252	598	2e-47	185
rs:WP_003440272	DNA topoisomerase III [Peptoclostridium difficile].	30.89	395	230	7	48	435	248	606	2e-47	184
rs:WP_042762169	hypothetical protein [Vibrio parahaemolyticus].	31.72	372	238	7	35	402	251	610	2e-47	183
rs:WP_039352756	DNA topoisomerase III [Chryseobacterium jeonii].	32.16	426	262	11	40	449	233	647	2e-47	184
rs:WP_021394124	DNA topoisomerase III family protein [Peptoclostridium difficile].	30.89	395	230	7	48	435	248	606	2e-47	184
rs:WP_003423232	DNA topoisomerase III [Peptoclostridium difficile].	30.53	393	234	6	48	435	248	606	2e-47	184
rs:WP_021413935	DNA topoisomerase III family protein [Peptoclostridium difficile].	30.53	393	234	6	48	435	248	606	2e-47	184
rs:WP_016359545	DNA topoisomerase III [Gemella sanguinis].	31.59	383	232	9	73	451	263	619	2e-47	184
rs:WP_009382803	DNA topoisomerase III [Staphylococcus massiliensis].	30.50	423	263	8	36	450	228	627	2e-47	184
rs:WP_021360748	DNA topoisomerase III family protein [Peptoclostridium difficile].	30.89	395	230	7	48	435	248	606	2e-47	184
rs:WP_022321312	DNA topoisomerase III [Parabacteroides merdae CAG:48].	31.34	367	241	8	37	401	230	587	2e-47	184
rs:WP_043834996	DNA topoisomerase III [Roseomonas aerilata].	33.15	371	225	8	40	392	230	595	2e-47	184
rs:WP_021417641	DNA topoisomerase III family protein [Peptoclostridium difficile].	30.89	395	230	7	48	435	248	606	2e-47	184
rs:WP_021377959	DNA topoisomerase III family protein [Peptoclostridium difficile].	30.89	395	230	7	48	435	248	606	2e-47	184
rs:WP_009905839	DNA topoisomerase III [Peptoclostridium difficile].	30.53	393	234	6	48	435	248	606	2e-47	184
rs:WP_000766774	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.54	429	264	12	36	448	244	654	2e-47	184
rs:WP_044115552	DNA topoisomerase III [Porphyromonas sp. KLE 1280].	35.83	360	211	12	38	385	237	588	2e-47	184
rs:WP_040085309	DNA topoisomerase III, partial [Escherichia coli].	31.66	338	208	6	119	443	1	328	2e-47	179
rs:WP_046451949	DNA topoisomerase III [Bacteroides sp. UNK.MGS-14].	31.34	367	241	8	37	401	230	587	2e-47	184
rs:WP_047840487	DNA topoisomerase III [Paenibacillus sp. VT-400].	32.29	415	244	10	33	439	230	615	2e-47	184
rs:WP_036097359	DNA topoisomerase III [Listeria floridensis].	31.76	403	252	7	38	435	231	615	2e-47	184
rs:WP_013308786	DNA topoisomerase III [Paenibacillus polymyxa].	31.83	399	235	9	38	426	233	604	2e-47	184
rs:WP_000766745	MULTISPECIES: DNA topoisomerase III [Bacillus].	31.00	429	262	12	36	448	244	654	2e-47	184
rs:WP_047440989	DNA topoisomerase III [Chryseobacterium sp. YR561].	32.61	414	264	10	40	451	233	633	2e-47	184
rs:WP_015040782	DNA topoisomerase iii [Bordetella parapertussis].	34.16	363	208	9	38	385	252	598	2e-47	185
rs:WP_021365580	DNA topoisomerase III family protein [Peptoclostridium difficile].	30.89	395	230	7	48	435	248	606	2e-47	184
rs:WP_033450699	DNA topoisomerase III [Bordetella bronchiseptica].	34.16	363	208	9	38	385	252	598	2e-47	185
rs:WP_016729072	DNA topoisomerase III [Peptoclostridium difficile].	31.14	395	229	7	48	435	248	606	2e-47	184
rs:WP_031849828	hypothetical protein [Vibrio parahaemolyticus].	31.72	372	238	7	35	402	251	610	2e-47	183
rs:WP_004368552	DNA topoisomerase III [Prevotella oralis].	32.91	398	241	13	17	402	211	594	2e-47	184
rs:WP_025585606	DNA topoisomerase III [Cupriavidus taiwanensis].	33.43	356	218	7	38	385	253	597	2e-47	185
rs:WP_036797036	hypothetical protein, partial [Leisingera caerulea].	32.37	417	249	13	36	431	260	664	2e-47	184
rs:WP_028168975	DNA topoisomerase III [Bradyrhizobium elkanii].	31.23	413	244	10	40	423	230	631	2e-47	184
rs:WP_028590812	DNA topoisomerase III [Paenibacillus panacisoli].	32.22	388	229	11	29	391	221	599	2e-47	184
rs:WP_033839942	DNA topoisomerase III [Bordetella bronchiseptica].	34.16	363	208	9	38	385	252	598	2e-47	185
rs:WP_042983184	DNA topoisomerase III [Bacillus mycoides].	30.23	430	268	10	36	450	244	656	2e-47	184
rs:WP_033456757	DNA topoisomerase III [Bordetella bronchiseptica].	34.16	363	208	9	38	385	252	598	2e-47	185
rs:WP_028406384	DNA topoisomerase III [Bacillus sp. J13].	33.17	413	230	11	38	435	233	614	2e-47	184
rs:WP_043934594	DNA topoisomerase III [Bacillus sp. EB01].	30.58	399	247	5	36	434	230	598	2e-47	184
rs:WP_043679321	DNA topoisomerase III [Castellaniella defragrans].	32.63	377	223	9	23	385	239	598	2e-47	185
rs:WP_024866752	DNA topoisomerase [Butyrivibrio sp. FCS014].	31.25	432	257	13	47	446	270	693	2e-47	186
rs:WP_010929538	MULTISPECIES: DNA topoisomerase III [Bordetella].	34.16	363	208	9	38	385	252	598	2e-47	185
rs:WP_015042051	DNA topoisomerase iii [Bordetella bronchiseptica].	34.16	363	208	9	38	385	252	598	2e-47	185
rs:WP_003815970	DNA topoisomerase III [Bordetella bronchiseptica].	34.16	363	208	9	38	385	252	598	3e-47	185
rs:WP_002188055	DNA topoisomerase III [Bacillus cereus].	30.43	437	273	12	36	454	244	667	3e-47	184
rs:WP_033471215	DNA topoisomerase III [Bordetella bronchiseptica].	34.16	363	208	9	38	385	252	598	3e-47	185
rs:WP_012354342	DNA topoisomerase III [Cupriavidus taiwanensis].	33.43	356	218	7	38	385	253	597	3e-47	185
rs:WP_003818222	DNA topoisomerase iii [Bordetella bronchiseptica].	34.16	363	208	9	38	385	252	598	3e-47	184
rs:WP_042997783	DNA topoisomerase III [Bordetella bronchiseptica].	34.16	363	208	9	38	385	252	598	3e-47	184
rs:WP_033469647	DNA topoisomerase III [Bordetella bronchiseptica].	34.16	363	208	9	38	385	252	598	3e-47	185
rs:WP_040434002	DNA topoisomerase III [Erysipelatoclostridium ramosum].	29.59	419	271	8	38	451	234	633	3e-47	184
tr:B0N116_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.59	419	271	8	38	451	245	644	3e-47	184
rs:WP_029516042	DNA topoisomerase III [Paenibacillus polymyxa].	31.06	396	242	7	38	426	233	604	3e-47	183
rs:WP_003145958	DNA topoisomerase III [Gemella haemolysans].	31.05	380	238	8	73	451	263	619	3e-47	183
rs:WP_028974183	hypothetical protein [Spirochaeta cellobiosiphila].	29.55	352	234	3	38	384	233	575	3e-47	183
rs:WP_006050553	DNA topoisomerase III [Burkholderia graminis].	34.82	359	206	9	38	385	253	594	3e-47	185
rs:WP_029969429	DNA topoisomerase III [Burkholderia sp. URHA0054].	34.82	359	206	9	38	385	253	594	3e-47	185
rs:WP_017763026	DNA topoisomerase III [Bacillus thuringiensis].	30.37	428	266	10	36	448	244	654	3e-47	183
rs:WP_033458597	DNA topoisomerase III [Bordetella bronchiseptica].	34.16	363	208	9	38	385	252	598	3e-47	184
rs:WP_016292371	DNA topoisomerase III [Lachnospiraceae bacterium 28-4].	32.93	416	248	13	40	445	119	513	3e-47	182
rs:WP_036668403	DNA topoisomerase III [Paenibacillus sp. FSL R5-192].	32.53	415	243	10	33	439	230	615	3e-47	183
rs:WP_029442008	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.37	428	266	10	36	448	244	654	3e-47	183
rs:WP_007172766	DNA topoisomerase III [Prevotella bergensis].	30.82	438	273	13	18	436	212	638	3e-47	183
rs:WP_010811329	DNA topoisomerase III [Ralstonia sp. GA3-3].	30.95	420	258	9	38	436	253	661	3e-47	185
rs:WP_023987041	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	32.08	399	234	9	38	426	233	604	3e-47	183
rs:WP_027776822	DNA topoisomerase III [Burkholderia caledonica].	35.10	359	205	9	38	385	253	594	3e-47	185
rs:WP_043793203	DNA topoisomerase III, partial [Delftia tsuruhatensis].	33.24	373	230	8	40	400	212	577	3e-47	185
rs:WP_013548841	DNA topoisomerase III [Bacteroides helcogenes].	31.18	372	244	8	28	396	257	619	3e-47	183
rs:WP_015900982	DNA topoisomerase III [Staphylococcus carnosus].	29.86	422	267	9	35	450	227	625	3e-47	183
rs:WP_027016978	DNA topoisomerase III [Comamonas composti].	34.32	373	224	8	40	399	263	627	3e-47	185
rs:WP_022777123	DNA topoisomerase [Butyrivibrio sp. AE3009].	31.32	431	255	12	47	446	272	692	3e-47	186
rs:WP_007179718	DNA topoisomerase III [Burkholderia sp. Ch1-1].	35.10	359	205	9	38	385	253	594	3e-47	184
rs:WP_043339226	DNA topoisomerase III [Belnapia moabensis].	33.16	395	230	10	63	439	252	630	3e-47	184
rs:WP_042407884	DNA topoisomerase III [Geobacillus caldoxylosilyticus].	30.02	433	271	12	36	453	245	660	3e-47	183
tr:U3UAG4_9BURK	SubName: Full=WGS project CAFE00000000 data, contig bkir_c137 {ECO:0000313|EMBL:CCD36403.1};	65.91	132	42	2	328	459	1	129	3e-47	171
rs:WP_006216705	DNA topoisomerase III [Achromobacter piechaudii].	35.53	380	212	11	22	385	236	598	3e-47	184
rs:WP_013804570	DNA topoisomerase III [Delftia sp. Cs1-4].	33.24	373	230	8	40	400	266	631	3e-47	185
rs:WP_045290378	DNA topoisomerase III [Bacillus aryabhattai].	31.00	400	240	7	37	435	231	595	3e-47	183
rs:WP_033829617	DNA topoisomerase III [Bacillus sp. KW-12].	29.89	435	273	8	35	453	243	661	3e-47	183
rs:WP_044396211	DNA topoisomerase III [Acidovorax temperans].	34.08	358	217	8	54	399	276	626	3e-47	185
rs:WP_017877597	DNA topoisomerase III [Janthinobacterium sp. CG3].	33.61	357	216	9	40	385	255	601	3e-47	184
rs:WP_042722218	DNA topoisomerase III, partial [Flavobacterium sp. B17].	34.77	325	206	6	61	384	254	573	3e-47	182
rs:WP_043904536	DNA topoisomerase III [Geobacillus stearothermophilus].	29.40	432	275	11	36	453	245	660	3e-47	183
rs:WP_020067280	DNA topoisomerase III [Burkholderia bryophila].	35.10	359	205	9	38	385	253	594	3e-47	184
rs:WP_006227776	DNA topoisomerase III [Achromobacter piechaudii].	35.09	379	215	10	22	385	236	598	3e-47	184
rs:WP_020566248	DNA topoisomerase III [Burkholderia sp. JPY347].	36.03	358	203	8	38	385	253	594	3e-47	184
rs:WP_022021451	DNA topoisomerase III [Bacteroides sp. CAG:661].	32.63	377	233	11	29	396	258	622	3e-47	183
rs:WP_043825380	DNA topoisomerase III [Delftia sp. RIT313].	33.24	373	230	8	40	400	266	631	3e-47	185
rs:WP_011486439	DNA topoisomerase III [Burkholderia xenovorans].	35.10	359	205	9	38	385	253	594	3e-47	184
rs:WP_028290036	DNA topoisomerase III [Olleya sp. VCSA23].	31.52	368	237	8	38	404	231	584	3e-47	183
rs:WP_000766731	DNA topoisomerase III [Bacillus cereus].	30.23	430	268	10	36	450	244	656	3e-47	183
rs:WP_034389805	DNA topoisomerase III [Delftia acidovorans].	33.24	373	230	8	40	400	266	631	3e-47	185
rs:WP_043541241	DNA topoisomerase III [Achromobacter sp. RTa].	35.81	363	202	10	38	385	252	598	3e-47	184
rs:WP_026714869	DNA topoisomerase III [Flavobacterium daejeonense].	32.02	356	227	8	38	392	231	572	3e-47	183
rs:WP_016819759	DNA topoisomerase III [Paenibacillus polymyxa].	30.75	400	242	8	36	426	231	604	3e-47	183
rs:WP_036943638	DNA topoisomerase [Pseudobacteroides cellulosolvens].	29.59	392	255	9	29	406	261	645	3e-47	183
rs:WP_029046468	DNA topoisomerase III [Cupriavidus sp. amp6].	33.15	356	219	7	38	385	253	597	3e-47	184
rs:WP_034265868	MULTISPECIES: DNA topoisomerase III [Bacillus].	30.75	400	241	7	37	435	231	595	4e-47	183
rs:WP_015016310	DNA topoisomerase III [Acidovorax sp. KKS102].	34.08	358	217	8	54	399	276	626	4e-47	185
tr:A0A0E8EUL7_BORPT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CRE12244.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRE12244.1};	34.16	363	208	9	38	385	252	598	4e-47	184
rs:WP_010929817	DNA topoisomerase III [Bordetella pertussis].	34.16	363	208	9	38	385	252	598	4e-47	184
rs:WP_042883607	DNA topoisomerase III [Cupriavidus necator].	33.15	356	219	7	38	385	253	597	4e-47	184
rs:WP_006745733	DNA topoisomerase III [Bacteroides coprosuis].	28.85	409	272	9	38	443	231	623	4e-47	182
rs:WP_026867002	DNA topoisomerase III [Jeotgalicoccus marinus].	30.09	422	259	7	23	435	222	616	4e-47	183
rs:WP_022309500	DNA topoisomerase III [Prevotella sp. CAG:474].	32.88	371	236	10	37	402	230	592	4e-47	183
rs:WP_016077855	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.37	428	266	10	36	448	244	654	4e-47	183
rs:WP_010494009	DNA topoisomerase III, partial [Paenibacillus elgii].	33.72	347	200	8	70	391	261	602	4e-47	182
rs:WP_028413452	DNA topoisomerase III [Bacillus sp. 278922_107].	30.75	400	241	7	37	435	231	595	4e-47	183
rs:WP_025277526	DNA topoisomerase III [Barnesiella viscericola].	32.80	375	236	8	37	407	230	592	4e-47	183
rs:WP_020897137	DNA topoisomerase III [Winogradskyella psychrotolerans].	31.28	438	266	12	38	454	231	654	4e-47	183
rs:WP_042415945	DNA topoisomerase III [Comamonas aquatica].	34.44	360	215	9	54	400	277	628	4e-47	185
rs:WP_035185002	DNA topoisomerase III [Bacillus coagulans].	31.11	450	272	13	18	446	222	654	4e-47	183
rs:WP_036650398	DNA topoisomerase III [Paenibacillus wynnii].	31.22	410	249	8	34	435	229	613	4e-47	183
rs:WP_033578902	MULTISPECIES: DNA topoisomerase III [Bacillus].	30.75	400	241	7	37	435	231	595	4e-47	183
rs:WP_016082039	DNA topoisomerase III [Bacillus cereus].	30.37	428	266	10	36	448	244	654	4e-47	183
rs:WP_004035914	DNA topoisomerase III [Clostridium sp. ASF356].	30.81	344	220	6	47	385	243	573	4e-47	183
rs:WP_029378515	DNA topoisomerase III [Staphylococcus xylosus].	29.68	411	268	7	43	450	235	627	4e-47	183
rs:WP_030102534	DNA topoisomerase III [Burkholderia sp. K24].	34.36	358	209	9	38	385	253	594	4e-47	184
rs:WP_012024355	DNA topoisomerase III [Flavobacterium johnsoniae].	31.40	430	265	12	38	454	231	643	4e-47	183
rs:WP_045469078	DNA topoisomerase III [Burkholderiales bacterium GJ-E10].	32.76	409	248	11	20	424	223	608	5e-47	183
rs:WP_022444575	DNA topoisomerase [Sutterella sp. CAG:351].	30.66	437	256	14	29	449	247	652	5e-47	184
rs:WP_036606074	DNA topoisomerase III [Paenibacillus sp. FSL H7-689].	32.29	415	244	10	33	439	230	615	5e-47	183
rs:WP_035202627	DNA topoisomerase III [Bacillus clausii].	31.50	400	250	11	56	448	267	649	5e-47	183
rs:WP_035613615	DNA topoisomerase, partial [Lachnospiraceae bacterium COE1].	32.32	393	229	8	35	393	258	647	5e-47	182
rs:WP_018418959	DNA topoisomerase III [Burkholderia sp. WSM4176].	34.64	358	208	9	38	385	253	594	5e-47	184
tr:A0A0A1H8R7_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.76	409	248	11	20	424	225	610	5e-47	183
rs:WP_014343006	DNA topoisomerase III, partial [Klebsiella pneumoniae].	37.87	235	139	2	151	385	2	229	5e-47	175
rs:WP_045524206	DNA topoisomerase III [Bacillus niacini].	29.48	424	273	9	36	446	244	654	5e-47	183
rs:WP_021639605	DNA topoisomerase [Clostridium sp. KLE 1755].	33.03	436	242	12	40	451	227	636	5e-47	182
rs:WP_019640460	DNA topoisomerase III [Paenibacillus fonticola].	31.93	404	242	7	34	428	229	608	5e-47	183
rs:WP_018662174	DNA topoisomerase III [Bacillus acidiproducens].	28.79	462	289	12	18	456	222	666	5e-47	183
rs:WP_013444792	DNA topoisomerase III [Paludibacter propionicigenes].	32.10	405	249	10	47	448	250	631	5e-47	182
rs:WP_038336868	DNA topoisomerase III [Empedobacter falsenii].	31.93	429	246	13	54	454	249	659	5e-47	182
rs:WP_018666382	DNA topoisomerase III [Bacteroides gallinarum].	32.35	371	237	9	30	396	257	617	5e-47	183
rs:WP_006835528	DNA topoisomerase III [Bacillus sp. SG-1].	29.40	432	275	11	36	453	244	659	5e-47	182
rs:WP_036786249	DNA topoisomerase III [Polaribacter sp. Hel1_33_49].	31.52	368	241	8	38	404	231	588	5e-47	183
rs:WP_048021026	DNA topoisomerase III [Bacillus aryabhattai].	30.50	400	242	7	37	435	231	595	5e-47	182
rs:WP_035684265	DNA topoisomerase III [Flavobacterium reichenbachii].	31.60	424	255	13	38	446	231	634	5e-47	183
rs:WP_031462889	DNA topoisomerase III [Paenibacillus polymyxa].	30.75	400	242	8	36	426	231	604	5e-47	182
rs:WP_022297090	DNA topoisomerase III [Clostridium sp. CAG:465].	34.47	351	197	11	72	398	298	639	5e-47	182
rs:WP_017550814	DNA topoisomerase III [Bacillus coagulans].	31.11	450	272	13	18	446	222	654	5e-47	182
rs:WP_036880865	DNA topoisomerase III [Porphyromonas sp. COT-239 OH1446].	30.42	424	263	10	38	444	236	644	5e-47	182
rs:WP_010529471	DNA topoisomerase III [Lentibacillus jeotgali].	31.68	404	253	10	59	454	268	656	6e-47	182
rs:WP_004407604	DNA topoisomerase III, partial [Pseudomonas syringae].	36.84	285	166	5	170	454	1	271	6e-47	175
rs:WP_035334438	MULTISPECIES: DNA topoisomerase III, partial [Bacillus].	32.45	413	240	16	47	452	242	622	6e-47	182
rs:WP_018967490	DNA topoisomerase III [Prevotella loescheii].	32.31	390	248	10	21	402	214	595	6e-47	182
rs:WP_012443177	DNA topoisomerase III [Erwinia tasmaniensis].	30.75	413	258	9	38	432	248	650	6e-47	182
rs:WP_023925335	DNA topoisomerase III [Prevotella nigrescens].	36.53	323	186	10	79	387	274	591	6e-47	182
rs:WP_000766777	DNA topoisomerase III [Bacillus cereus].	30.77	429	263	11	36	448	244	654	6e-47	182
rs:WP_028197702	DNA topoisomerase III [Burkholderia fungorum].	34.36	358	209	9	38	385	253	594	6e-47	184
rs:WP_023984861	DNA topoisomerase III [Prevotella oralis].	32.91	398	241	13	17	402	211	594	6e-47	182
rs:WP_025677653	DNA topoisomerase III [Paenibacillus massiliensis].	31.96	388	230	11	29	391	221	599	6e-47	183
rs:WP_022045540	DNA topoisomerase [Roseburia sp. CAG:18].	30.52	426	261	10	47	446	271	687	6e-47	185
rs:WP_039375166	DNA topoisomerase III, partial [Mumia flava].	34.26	359	209	9	38	385	253	595	6e-47	182
rs:WP_043966410	DNA topoisomerase III [Anoxybacillus thermarum].	29.61	439	246	11	36	459	230	620	6e-47	182
rs:WP_024813405	DNA topoisomerase III [Acidovorax sp. JHL-3].	33.06	372	230	8	40	399	266	630	6e-47	184
rs:WP_019387032	DNA topoisomerase III [Arenitalea lutea].	29.98	427	275	11	38	454	231	643	6e-47	183
rs:WP_012202816	DNA topoisomerase III [Delftia acidovorans].	33.24	373	230	8	40	400	266	631	6e-47	184
rs:WP_014710026	DNA topoisomerase III [Prevotella intermedia].	31.46	391	247	11	18	397	217	597	6e-47	182
rs:WP_048344636	topoisomerase I [Lactobacillus mucosae].	30.94	417	254	13	57	454	269	670	6e-47	182
rs:WP_044624791	DNA topoisomerase III [Tamlana nanhaiensis].	32.70	370	232	9	18	385	212	566	6e-47	183
rs:WP_046099940	DNA topoisomerase III [Staphylococcus carnosus].	29.62	422	268	9	35	450	227	625	6e-47	182
rs:WP_044039552	DNA topoisomerase III [Clostridium sp. M2/40].	29.61	456	275	13	22	446	245	685	6e-47	182
rs:WP_016134173	DNA topoisomerase III [Bacillus cereus].	30.23	430	268	10	36	450	244	656	6e-47	182
rs:WP_008790738	MULTISPECIES: DNA topoisomerase III [Coprobacillus].	31.10	418	257	10	38	445	234	630	6e-47	182
tr:A0A0D0Q8E3_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.61	439	246	11	36	459	231	621	6e-47	182
rs:WP_027201773	DNA topoisomerase III [Butyricimonas virosa].	28.70	439	275	10	37	454	230	651	6e-47	182
rs:WP_035326368	DNA topoisomerase III [Bacillus firmus].	29.26	417	252	8	36	446	230	609	6e-47	182
rs:WP_033534309	DNA topoisomerase III [Bordetella trematum].	34.72	409	236	10	38	431	252	644	6e-47	184
rs:WP_008449295	DNA topoisomerase III [Prevotella amnii].	31.09	357	221	10	37	375	235	584	6e-47	182
rs:WP_027391237	DNA topoisomerase III [Aquimarina latercula].	32.12	358	225	8	38	392	231	573	7e-47	182
rs:WP_016833774	DNA topoisomerase III [Herbaspirillum lusitanum].	34.27	356	212	10	40	385	255	598	7e-47	184
rs:WP_018436954	DNA topoisomerase III [Burkholderia sp. JPY251].	34.08	358	210	9	38	385	253	594	7e-47	184
rs:WP_047385938	DNA topoisomerase III [Bacillus cereus].	30.77	429	263	11	36	448	244	654	7e-47	182
rs:WP_013744085	DNA topoisomerase III [Pusillimonas sp. T7-7].	33.88	363	209	9	38	385	252	598	7e-47	184
rs:WP_027419728	DNA topoisomerase III [Crocinitomix catalasitica].	33.05	348	218	9	39	384	232	566	7e-47	182
rs:WP_016304003	DNA topoisomerase III [Lachnospiraceae bacterium A2].	33.33	363	217	5	54	396	249	606	7e-47	182
rs:WP_025514931	DNA topoisomerase III [Bordetella trematum].	34.72	409	236	10	38	431	252	644	7e-47	184
rs:WP_009235005	DNA topoisomerase III [Prevotella sp. oral taxon 472].	32.31	390	248	10	21	402	214	595	7e-47	182
rs:WP_027281816	DNA topoisomerase III [Roseomonas gilardii].	34.62	364	208	11	63	402	256	613	7e-47	182
rs:WP_047218931	DNA topoisomerase III [Delftia lacustris].	33.24	373	230	8	40	400	266	631	7e-47	184
tr:D5W9E3_BURSC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.08	358	210	9	38	385	270	611	7e-47	184
rs:WP_008462312	DNA topoisomerase III [Flavobacterium sp. F52].	31.76	425	255	12	38	446	231	636	7e-47	182
tr:E0RWM5_BUTPB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.37	484	269	17	3	446	244	699	7e-47	185
rs:WP_016449409	DNA topoisomerase III [Delftia acidovorans].	33.24	373	230	8	40	400	266	631	7e-47	184
rs:WP_034368856	MULTISPECIES: DNA topoisomerase III [Delftia].	33.24	373	230	8	40	400	266	631	7e-47	184
rs:WP_016099578	DNA topoisomerase III [Bacillus cereus].	31.36	405	250	12	57	450	267	654	7e-47	182
rs:WP_042748761	topoisomerase I [Lactococcus lactis].	30.43	437	265	14	38	454	252	669	8e-47	182
rs:WP_041734236	DNA topoisomerase III [Burkholderia sp. CCGE1002].	34.08	358	210	9	38	385	253	594	8e-47	183
rs:WP_032361994	DNA topoisomerase III, partial [Escherichia coli].	33.87	313	193	4	37	339	245	553	8e-47	181
rs:WP_025815981	DNA topoisomerase III [Prevotella shahii].	31.44	388	253	8	21	401	214	595	8e-47	182
rs:WP_000114570	DNA topoisomerase III [Bacillus cereus].	31.85	405	248	12	57	450	267	654	8e-47	182
rs:WP_043366110	DNA topoisomerase III, partial [Belnapia sp. F-4-1].	33.60	375	206	10	63	407	252	613	8e-47	182
rs:WP_000766772	DNA topoisomerase III [Bacillus cereus].	33.80	355	218	9	36	385	244	586	8e-47	182
rs:WP_042355746	DNA topoisomerase III [Bacillus sp. MT2].	29.06	437	276	11	36	456	244	662	8e-47	182
rs:WP_031552787	DNA topoisomerase III [Gemella sanguinis].	31.07	383	234	9	73	451	263	619	8e-47	182
rs:WP_026675398	DNA topoisomerase III [Bacillus bogoriensis].	29.33	433	271	12	36	453	244	656	8e-47	182
rs:WP_012093963	DNA topoisomerase III [Bacillus cytotoxicus].	33.05	354	222	7	36	385	244	586	8e-47	182
rs:WP_008157627	DNA topoisomerase III [Achromobacter arsenitoxydans].	34.56	379	217	9	22	385	236	598	8e-47	183
rs:WP_037250833	MULTISPECIES: DNA topoisomerase III, partial [Roseomonas].	33.33	387	227	11	40	402	230	609	9e-47	182
rs:WP_018339522	DNA topoisomerase III [Butyricimonas synergistica].	29.23	431	266	11	37	446	230	642	9e-47	182
rs:WP_011616268	DNA topoisomerase III [Cupriavidus necator].	30.71	420	259	9	38	436	253	661	9e-47	183
tr:R6E059_9BACE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:CDA83657.1};	32.25	369	235	10	31	396	253	609	9e-47	182
rs:WP_027633415	hypothetical protein [Clostridium hydrogeniformans].	30.37	405	249	9	47	446	252	628	9e-47	182
rs:WP_018884314	DNA topoisomerase III [Paenibacillus massiliensis].	31.96	388	230	11	29	391	221	599	9e-47	182
rs:WP_048506450	DNA topoisomerase III [Chryseobacterium angstadtii].	33.65	416	257	13	40	451	233	633	9e-47	182
rs:WP_043775642	DNA topoisomerase III, partial [Desulfomicrobium escambiense].	33.53	343	208	6	50	385	253	582	1e-46	181
rs:WP_022123622	DNA topoisomerase [Clostridium sp. CAG:510].	31.04	451	259	17	47	459	270	706	1e-46	185
rs:WP_008792719	DNA topoisomerase III [Coprobacillus sp. 8_2_54BFAA].	29.36	419	272	8	38	451	234	633	1e-46	182
rs:WP_025675355	DNA topoisomerase III [Paenibacillus polymyxa].	31.17	401	239	9	36	426	231	604	1e-46	182
rs:WP_017751809	hypothetical protein [Clostridium tyrobutyricum].	30.83	399	248	8	36	425	230	609	1e-46	182
rs:WP_044220056	DNA topoisomerase III [Flammeovirga pacifica].	31.96	363	238	7	37	396	230	586	1e-46	182
rs:WP_040612006	DNA topoisomerase III, partial [Odoribacter laneus].	29.34	426	265	10	39	446	232	639	1e-46	181
rs:WP_044820516	DNA topoisomerase III [Bacteroides fragilis].	32.95	352	222	9	49	396	258	599	1e-46	182
rs:WP_036625876	DNA topoisomerase III [Paenibacillus macerans].	31.54	409	245	7	33	435	230	609	1e-46	182
rs:WP_011299539	DNA topoisomerase III [Cupriavidus pinatubonensis].	31.38	427	247	10	38	436	253	661	1e-46	183
rs:WP_027199369	DNA topoisomerase III [Burkholderia sprentiae].	34.36	358	209	9	38	385	253	594	1e-46	183
rs:WP_018312052	DNA topoisomerase III [Cupriavidus sp. UYPR2.512].	33.15	356	219	7	38	385	253	597	1e-46	183
rs:WP_008147589	DNA topoisomerase III [Parabacteroides johnsonii].	31.38	376	229	10	37	401	230	587	1e-46	182
rs:WP_031922391	DNA topoisomerase III, partial [Staphylococcus aureus].	29.01	424	269	9	35	450	227	626	1e-46	181
rs:WP_028309380	DNA topoisomerase III [Desulfitibacter alkalitolerans].	35.59	340	202	7	43	377	231	558	1e-46	182
rs:WP_044655159	DNA topoisomerase III [Bacteroides acidifaciens].	32.25	369	235	10	31	396	253	609	1e-46	182
rs:WP_035792465	DNA topoisomerase [Butyrivibrio sp. AE3006].	30.27	479	269	15	3	446	244	692	1e-46	184
rs:WP_017895874	hypothetical protein [Clostridium tyrobutyricum].	30.83	399	248	8	36	425	230	609	1e-46	182
rs:WP_032590617	DNA topoisomerase III [Bacteroides fragilis].	32.95	352	222	9	49	396	268	609	1e-46	182
rs:WP_048010525	DNA topoisomerase III [Bacillus firmus].	28.94	432	262	9	36	459	230	624	1e-46	182
rs:WP_045265866	DNA topoisomerase III [Comamonas aquatica].	33.89	360	217	9	54	400	277	628	1e-46	184
rs:WP_046803989	DNA topoisomerase III [Achromobacter sp. LC458].	34.56	379	217	9	22	385	236	598	1e-46	183
tr:A0A0D0S1Q1_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.90	354	218	8	36	385	242	583	1e-46	181
rs:WP_033615686	DNA topoisomerase, partial [Enterococcus faecium].	32.45	416	245	11	52	452	40	434	1e-46	179
rs:WP_013369460	DNA topoisomerase III [Paenibacillus polymyxa].	30.75	400	242	8	36	426	231	604	1e-46	182
rs:WP_028904646	DNA topoisomerase III [Prevotella intermedia].	31.20	391	248	11	18	397	217	597	1e-46	181
rs:WP_032822570	topoisomerase I [Oenococcus oeni].	30.58	412	243	12	66	454	278	669	1e-46	182
tr:T1CM99_9HELI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.10	373	237	5	35	396	239	602	1e-46	181
rs:WP_023466257	DNA topoisomerase [Lactobacillus fermentum].	30.46	417	256	13	57	454	269	670	1e-46	182
rs:WP_010464480	DNA topoisomerase III [Acidovorax radicis].	33.70	359	219	8	54	400	276	627	1e-46	184
tr:A0A014MIW0_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	33.89	360	217	9	54	400	265	616	1e-46	183
rs:WP_042795811	DNA topoisomerase III [Achromobacter xylosoxidans].	35.54	363	203	9	38	385	252	598	1e-46	183
rs:WP_047326379	DNA topoisomerase III [Delftia tsuruhatensis].	33.24	373	230	8	40	400	266	631	1e-46	184
rs:WP_047906529	DNA topoisomerase III [Pandoraea faecigallinarum].	34.31	341	208	8	55	385	270	604	1e-46	183
tr:H1DJY9_9PORP	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.34	426	265	10	39	446	232	639	1e-46	181
rs:WP_034678541	DNA topoisomerase III [Chryseobacterium formosense].	31.23	413	269	8	40	450	233	632	1e-46	181
rs:WP_002592974	DNA topoisomerase III [[Clostridium] clostridioforme].	34.39	378	224	8	56	425	243	604	1e-46	181
rs:WP_043378607	DNA topoisomerase III [Comamonas aquatica].	33.89	360	217	9	54	400	277	628	1e-46	183
rs:WP_032101858	DNA topoisomerase III, partial [Anoxybacillus flavithermus].	30.54	406	237	8	36	435	230	596	1e-46	181
rs:WP_022048204	DNA topoisomerase III [Odoribacter laneus CAG:561].	29.91	428	260	12	39	446	232	639	1e-46	181
tr:A0NKA9_OENOE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.39	408	249	12	66	454	285	676	1e-46	181
rs:WP_011797628	DNA topoisomerase III [Acidovorax citrulli].	33.88	366	223	8	47	400	271	629	1e-46	183
rs:WP_044453283	DNA topoisomerase III [Pandoraea vervacti].	34.31	341	208	8	55	385	270	604	1e-46	183
rs:WP_036176604	DNA topoisomerase III [Lysinibacillus massiliensis].	30.92	414	248	11	60	450	270	668	1e-46	181
rs:WP_047912776	DNA topoisomerase III [Paenibacillus sp. TCA20].	30.27	413	251	9	38	439	233	619	1e-46	181
rs:WP_028319719	DNA topoisomerase III [Desulfobulbus elongatus].	31.37	408	251	10	21	418	241	629	1e-46	182
rs:WP_042165346	DNA topoisomerase III [Paenibacillus sp. G1].	31.28	406	239	8	38	428	234	614	1e-46	181
rs:WP_033553424	DNA topoisomerase III [Escherichia coli].	30.16	431	276	8	31	443	240	663	1e-46	181
rs:WP_036235380	DNA topoisomerase III [Massilia sp. JS1662].	34.13	375	222	10	22	385	237	597	1e-46	182
rs:WP_046823179	DNA topoisomerase III [Clostridium sp. JC272].	29.17	384	234	7	47	425	244	594	1e-46	181
rs:WP_032576270	DNA topoisomerase III [Bacteroides fragilis].	32.95	352	222	9	49	396	268	609	1e-46	181
rs:WP_022334396	DNA topoisomerase [Clostridium sp. CAG:452].	31.09	402	249	12	22	398	245	643	1e-46	181
rs:WP_029192188	DNA topoisomerase III [Paenibacillus harenae].	31.36	405	239	9	38	428	234	613	1e-46	181
rs:WP_017070755	DNA topoisomerase III, partial [Vibrio crassostreae].	38.30	235	140	1	36	270	255	484	1e-46	179
rs:WP_042327278	DNA topoisomerase III [Burkholderia ginsengisoli].	35.10	359	205	9	38	385	253	594	2e-46	182
rs:WP_009436399	DNA topoisomerase III [Prevotella sp. oral taxon 473].	31.88	389	215	11	47	396	326	703	2e-46	182
rs:WP_034474891	DNA topoisomerase [Butyrivibrio proteoclasticus].	30.37	484	269	17	3	446	244	699	2e-46	184
rs:WP_028593375	DNA topoisomerase III [Paenibacillus assamensis].	29.56	406	259	6	34	435	229	611	2e-46	181
rs:WP_031833188	DNA topoisomerase III [Staphylococcus aureus].	29.01	424	269	9	35	450	227	626	2e-46	181
rs:WP_037990282	DNA topoisomerase III [Tepidiphilus margaritifer].	34.10	393	230	9	40	421	255	629	2e-46	182
rs:WP_014110704	DNA topoisomerase III [Taylorella asinigenitalis].	32.78	360	215	7	38	385	253	597	2e-46	182
rs:WP_028993922	DNA topoisomerase III [Azonexus hydrophilus].	33.18	422	232	15	40	435	255	652	2e-46	182
rs:WP_035445052	DNA topoisomerase III, partial [Bacillus sp. UNC41MFS5].	31.00	429	260	14	36	446	244	654	2e-46	181
rs:WP_029485981	DNA topoisomerase [Enterococcus faecium].	32.27	409	235	15	61	454	165	546	2e-46	180
rs:WP_032824678	topoisomerase I [Oenococcus oeni].	30.58	412	243	12	66	454	278	669	2e-46	181
rs:WP_010723882	DNA topoisomerase III [Enterococcus faecium].	32.27	409	235	15	61	454	165	546	2e-46	180
rs:WP_044638498	DNA topoisomerase III [Siansivirga zeaxanthinifaciens].	29.11	426	279	10	38	454	231	642	2e-46	181
rs:WP_047400347	DNA topoisomerase III [Chryseobacterium sp. YR460].	31.81	415	266	9	40	451	233	633	2e-46	181
rs:WP_002318450	DNA topoisomerase, partial [Enterococcus faecium].	32.59	405	231	15	65	454	120	497	2e-46	180
rs:WP_004165034	DNA topoisomerase [Oenococcus oeni].	30.58	412	243	12	66	454	278	669	2e-46	181
rs:WP_002338064	DNA topoisomerase III [Enterococcus faecium].	32.27	409	235	15	61	454	165	546	2e-46	180
rs:WP_033448977	DNA topoisomerase III [Bordetella bronchiseptica].	33.88	363	209	9	38	385	252	598	2e-46	182
rs:WP_022617262	DNA topoisomerase III [Peptoclostridium difficile].	30.53	393	234	6	48	435	248	606	2e-46	181
rs:WP_010890637	protein TrsI [Lactococcus lactis].	30.21	437	266	14	38	454	252	669	2e-46	181
rs:WP_035976377	DNA topoisomerase III, partial [Bradyrhizobium sp. th.b2].	31.62	389	231	11	40	406	230	605	2e-46	181
rs:WP_003430396	DNA topoisomerase III [Peptoclostridium difficile].	30.53	393	234	6	48	435	248	606	2e-46	181
rs:WP_018462451	DNA topoisomerase III [Prevotella paludivivens].	31.28	390	250	9	18	396	212	594	2e-46	181
rs:WP_000962891	hypothetical protein, partial [Vibrio cholerae].	40.97	227	127	1	159	385	2	221	2e-46	173
rs:WP_025141104	DNA topoisomerase III [Achromobacter sp. DH1f].	34.26	394	225	10	10	385	221	598	2e-46	182
rs:WP_029656583	DNA topoisomerase, partial [Enterococcus faecalis].	32.69	416	244	11	52	452	40	434	2e-46	178
rs:WP_002343079	DNA topoisomerase III [Enterococcus faecium].	32.27	409	235	15	61	454	165	546	2e-46	180
rs:WP_041848210	DNA topoisomerase III [Bacillus thermoamylovorans].	29.51	427	269	9	35	446	243	652	2e-46	181
rs:WP_031885526	DNA topoisomerase III [Staphylococcus aureus].	29.01	424	269	9	35	450	227	626	2e-46	181
rs:WP_021388038	DNA topoisomerase III family protein [Peptoclostridium difficile].	30.53	393	234	6	48	435	248	606	2e-46	181
rs:WP_045391803	hypothetical protein [Vibrio rotiferianus].	29.53	359	239	6	36	392	250	596	2e-46	180
rs:WP_040102123	DNA topoisomerase III [Paenibacillus polymyxa].	30.50	400	243	8	36	426	231	604	2e-46	181
rs:WP_029268835	DNA topoisomerase III [Flavobacterium sp. KJJ].	31.46	426	253	14	38	446	231	634	2e-46	181
rs:WP_034043867	DNA topoisomerase III [Flaviramulus ichthyoenteri].	30.09	422	264	12	38	446	231	634	2e-46	181
rs:WP_013739402	DNA topoisomerase III [Sphaerochaeta coccoides].	30.92	359	235	6	34	385	229	581	2e-46	182
rs:WP_044405324	DNA topoisomerase III [Rhodopseudomonas palustris].	31.58	380	226	8	63	418	252	621	2e-46	181
rs:WP_024973868	DNA topoisomerase III [Ralstonia pickettii].	33.50	403	230	13	38	425	253	632	2e-46	182
rs:WP_035208559	DNA topoisomerase III, partial [Acidovorax avenae].	33.88	366	223	8	47	400	271	629	2e-46	183
rs:WP_017498188	DNA topoisomerase III [Flavobacterium sp. WG21].	31.37	424	256	13	38	446	231	634	2e-46	181
rs:WP_009239400	MULTISPECIES: DNA topoisomerase III [Ralstonia].	33.75	403	229	13	38	425	253	632	2e-46	182
rs:WP_024977063	DNA topoisomerase III [Ralstonia pickettii].	33.75	403	229	13	38	425	253	632	2e-46	182
rs:WP_019451929	DNA topoisomerase III [Cupriavidus sp. BIS7].	33.05	357	219	8	38	385	253	598	2e-46	182
rs:WP_031910263	DNA topoisomerase III, partial [Staphylococcus aureus].	28.77	424	270	9	35	450	57	456	2e-46	178
rs:WP_041726130	hypothetical protein [Caldisericum exile].	30.46	394	250	7	36	421	236	613	2e-46	181
tr:I0GKW5_CALEA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.46	394	250	7	36	421	235	612	2e-46	181
rs:WP_046835674	DNA topoisomerase III [Staphylococcus succinus].	28.68	408	270	7	46	450	238	627	2e-46	181
rs:WP_021909342	DNA topoisomerase III [Prevotella sp. CAG:755].	33.77	379	226	10	36	406	240	601	2e-46	181
rs:WP_031868979	DNA topoisomerase III, partial [Staphylococcus aureus].	28.77	424	270	9	35	450	15	414	2e-46	178
rs:WP_026462624	DNA topoisomerase III [Adhaeribacter aquaticus].	32.28	378	240	9	37	406	230	599	3e-46	181
rs:WP_041964452	DNA topoisomerase III [Bacillus selenatarsenatis].	29.48	407	244	7	35	434	229	599	3e-46	181
rs:WP_037476926	DNA topoisomerase III [Sphaerotilus natans].	34.21	380	216	10	40	400	262	626	3e-46	182
rs:WP_013596902	DNA topoisomerase III [Acidovorax avenae].	33.88	366	223	8	47	400	271	629	3e-46	182
rs:WP_041902077	DNA topoisomerase III [Bacillus thermoamylovorans].	29.51	427	269	9	35	446	243	652	3e-46	181
rs:WP_036883579	DNA topoisomerase III [Porphyromonas gingivicanis].	32.08	371	235	6	43	401	236	601	3e-46	180
rs:WP_033405780	hypothetical protein, partial [Kiloniella laminariae].	33.68	383	214	13	29	377	229	605	3e-46	181
rs:WP_002336691	DNA topoisomerase III [Enterococcus faecium].	32.52	409	234	16	61	454	165	546	3e-46	180
rs:WP_042713119	DNA topoisomerase III, partial [Klebsiella cf. planticola B43].	36.92	279	168	5	155	433	3	273	3e-46	172
rs:WP_045241973	DNA topoisomerase III [Burkholderiaceae bacterium 16].	30.71	420	257	9	38	436	253	659	3e-46	182
rs:WP_045146679	DNA topoisomerase III [Peptoclostridium difficile].	30.03	393	236	6	48	435	248	606	3e-46	181
rs:WP_034768980	DNA topoisomerase III [Bacillus thermoamylovorans].	29.51	427	269	9	35	446	243	652	3e-46	181
rs:WP_009903124	DNA topoisomerase III [Peptoclostridium difficile].	30.63	395	231	7	48	435	248	606	3e-46	181
rs:WP_045205150	DNA topoisomerase III [Burkholderiaceae bacterium 26].	33.75	403	229	13	38	425	253	632	3e-46	182
rs:WP_026432170	DNA topoisomerase III [Acidovorax oryzae].	33.88	366	223	8	47	400	271	629	3e-46	182
rs:WP_039011607	DNA topoisomerase III [Cupriavidus sp. IDO].	32.58	356	221	7	38	385	253	597	3e-46	182
rs:WP_034743444	DNA topoisomerase III [Bacillus wakoensis].	30.67	450	247	14	36	452	244	661	3e-46	181
rs:WP_004362216	DNA topoisomerase III [Prevotella nigrescens].	36.22	323	187	10	79	387	274	591	3e-46	180
rs:WP_012436841	MULTISPECIES: DNA topoisomerase III [Ralstonia].	33.50	403	230	13	38	425	253	632	3e-46	182
rs:WP_004366086	DNA topoisomerase III [Prevotella nigrescens].	35.44	333	192	11	79	397	274	597	3e-46	180
rs:WP_002340557	DNA topoisomerase III [Enterococcus faecium].	31.89	417	253	10	52	455	265	663	3e-46	180
rs:WP_047351249	DNA topoisomerase III, partial [Diaphorobacter sp. J5-51].	33.51	367	223	9	47	400	270	628	3e-46	182
rs:WP_018871403	DNA topoisomerase III [Thioalkalivibrio sp. ALgr3].	33.07	378	229	8	38	408	246	606	3e-46	180
rs:WP_028728532	DNA topoisomerase III [Parabacteroides gordonii].	31.10	373	242	9	37	405	230	591	3e-46	180
rs:WP_021166216	hypothetical protein [Lactococcus lactis].	30.21	437	266	14	38	454	252	669	3e-46	180
rs:WP_039702391	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	3e-46	180
rs:WP_022453611	DNA topoisomerase [Prevotella sp. CAG:873].	31.93	379	233	11	54	417	195	563	3e-46	180
rs:WP_046850419	DNA topoisomerase III [Nitrosomonas communis].	30.96	394	250	9	40	425	255	634	3e-46	181
tr:A0A0D6FEB7_ALCXX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	35.26	363	204	9	38	385	252	598	3e-46	181
rs:WP_034720218	DNA topoisomerase III [Chryseobacterium antarcticum].	31.80	412	254	9	61	456	254	654	3e-46	180
rs:WP_004085584	DNA topoisomerase III [Xylella fastidiosa].	46.95	213	73	2	121	333	1	173	3e-46	170
rs:WP_044254218	DNA topoisomerase [Rhodopirellula sp. SWK7].	32.87	362	229	8	47	406	257	606	3e-46	181
rs:WP_048021333	DNA topoisomerase III [Bacillus aryabhattai].	31.29	441	258	14	36	453	244	662	4e-46	180
rs:WP_035331343	DNA topoisomerase III [Bacillus firmus].	29.26	434	273	11	36	453	244	659	4e-46	180
rs:WP_020431209	hypothetical protein, partial [Paenibacillus riograndensis].	34.10	349	203	8	70	396	2	345	4e-46	178
rs:WP_013551991	DNA topoisomerase III [Cellulophaga algicola].	30.28	426	261	12	38	446	231	637	4e-46	181
rs:WP_027678685	DNA topoisomerase III [Ralstonia sp. UNC404CL21Col].	33.50	403	230	13	38	425	253	632	4e-46	181
rs:WP_038211376	DNA topoisomerase III [Xylella fastidiosa].	46.48	213	74	2	121	333	1	173	4e-46	169
rs:WP_028996896	DNA topoisomerase III [Azohydromonas australica].	34.70	366	203	11	40	385	264	613	4e-46	181
tr:F3GEY9_PSESJ	SubName: Full=Orf50 {ECO:0000313|EMBL:EGH45639.1};	34.33	335	189	8	141	459	2	321	4e-46	175
rs:WP_025842430	DNA topoisomerase III [Porphyromonas gingivicanis].	32.08	371	235	6	43	401	236	601	4e-46	179
rs:WP_025025884	DNA topoisomerase III [Bacillus mannanilyticus].	30.05	366	241	4	38	401	266	618	4e-46	180
rs:WP_027077441	DNA topoisomerase III [Maribacter antarcticus].	30.90	424	256	11	38	446	231	632	4e-46	180
rs:WP_031921622	DNA topoisomerase III, partial [Staphylococcus aureus].	28.77	424	270	9	35	450	41	440	4e-46	178
tr:F7SZR1_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	35.26	363	204	9	38	385	232	578	4e-46	181
tr:M5T3X4_9PLAN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.87	362	229	8	47	406	258	607	4e-46	181
rs:WP_025799526	DNA topoisomerase III [Prevotella saccharolytica].	31.54	390	250	9	21	402	214	594	4e-46	180
rs:WP_035554140	DNA topoisomerase III [Burkholderia sp. 9120].	35.10	359	205	9	38	385	253	594	4e-46	181
rs:WP_029800262	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	40.95	210	124	0	36	245	255	464	4e-46	177
rs:WP_046740998	DNA topoisomerase III [Lampropedia sp. CT6].	34.06	367	215	9	40	385	267	627	4e-46	182
rs:WP_028561132	DNA topoisomerase III [Paenibacillus pinihumi].	33.77	382	225	10	40	401	234	607	4e-46	180
rs:WP_025443192	hypothetical protein [Vibrio parahaemolyticus].	31.18	372	240	7	35	402	251	610	4e-46	179
rs:WP_038065733	hypothetical protein, partial [Thermodesulfovibrio thiophilus].	33.05	351	218	6	29	377	249	584	4e-46	179
rs:WP_046447476	DNA topoisomerase III [Acinetobacter sp. N54.MGS-139].	33.67	398	233	12	40	425	254	632	4e-46	181
rs:WP_031786141	DNA topoisomerase III, partial [Staphylococcus aureus].	28.77	424	270	9	35	450	56	455	4e-46	178
rs:WP_040597623	DNA topoisomerase III [Alloprevotella rava].	32.13	361	235	6	51	406	269	624	4e-46	180
rs:WP_009520705	MULTISPECIES: DNA topoisomerase III [Hydrogenophaga].	32.43	367	227	9	47	400	277	635	4e-46	182
rs:WP_015856075	DNA topoisomerase III [Ralstonia pickettii].	33.50	403	230	13	38	425	253	632	4e-46	181
rs:WP_011633516	DNA topoisomerase III [Nitrosomonas eutropha].	31.76	403	254	10	40	435	255	643	4e-46	181
rs:WP_036647111	DNA topoisomerase III [Paenibacillus pini].	31.05	380	236	10	40	401	234	605	4e-46	180
rs:WP_033858676	DNA topoisomerase III, partial [Staphylococcus aureus].	28.77	424	270	9	35	450	55	454	4e-46	178
rs:WP_035359824	DNA topoisomerase III [Achromobacter insuavis].	35.26	363	204	9	38	385	252	598	5e-46	181
rs:WP_036854427	DNA topoisomerase III [Prevotella amnii].	30.81	357	222	10	37	375	235	584	5e-46	179
rs:WP_007411728	DNA topoisomerase III [Prevotella sp. MSX73].	30.63	395	257	8	24	406	217	606	5e-46	180
tr:I7IL22_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.50	360	216	7	38	385	253	597	5e-46	181
rs:WP_019976661	hypothetical protein [Empedobacter brevis].	31.55	431	245	14	54	454	249	659	5e-46	180
rs:WP_022090677	DNA topoisomerase III [Clostridium sp. CAG:492].	32.26	372	226	12	47	398	272	637	5e-46	179
rs:WP_019035605	DNA topoisomerase III [Prevotella amnii].	30.81	357	222	10	37	375	235	584	5e-46	179
rs:WP_015262647	DNA topoisomerase III [Desulfitobacterium dichloroeliminans].	29.32	457	254	12	42	448	275	712	5e-46	180
rs:WP_007870325	DNA topoisomerase III [Polaromonas sp. CF318].	32.05	365	231	6	47	400	272	630	5e-46	182
rs:WP_032568947	DNA topoisomerase III [Bacteroides fragilis].	32.67	352	223	9	49	396	268	609	5e-46	180
rs:WP_007808804	DNA topoisomerase III [Flavobacterium sp. CF136].	30.00	430	271	13	38	454	231	643	5e-46	180
rs:WP_004628306	DNA topoisomerase III [Ralstonia pickettii].	33.50	403	230	13	38	425	253	632	5e-46	181
rs:WP_043071384	DNA topoisomerase III [Aneurinibacillus migulanus].	31.51	438	264	12	36	453	244	665	5e-46	180
rs:WP_033615842	DNA topoisomerase, partial [Enterococcus faecium].	32.21	416	246	11	52	452	40	434	5e-46	177
rs:WP_007416564	DNA topoisomerase III [Pedosphaera parvula].	33.78	370	220	9	40	399	255	609	5e-46	181
rs:WP_045850186	hypothetical protein [Domibacillus enclensis].	28.96	442	284	9	22	450	227	651	5e-46	180
rs:WP_035865596	DNA topoisomerase III [Cupriavidus sp. SK-3].	31.74	397	247	8	38	426	253	633	6e-46	181
rs:WP_002339858	DNA topoisomerase III [Enterococcus faecium].	32.59	405	231	15	65	454	169	546	6e-46	178
rs:WP_023872752	MULTISPECIES: DNA topoisomerase III [Pandoraea].	34.30	344	204	10	55	385	270	604	6e-46	181
rs:WP_039111128	DNA topoisomerase III [Flavobacterium sp. KMS].	30.05	426	259	13	38	446	231	634	6e-46	180
rs:WP_000838495	DNA topoisomerase III [Staphylococcus aureus].	29.01	424	269	9	35	450	227	626	6e-46	179
rs:WP_027799096	DNA topoisomerase III [Burkholderia dilworthii].	34.82	359	206	9	38	385	253	594	6e-46	181
rs:WP_000114567	DNA topoisomerase III [Bacillus thuringiensis].	31.31	412	249	12	57	454	267	658	6e-46	179
rs:WP_023625750	DNA topoisomerase III [Bacillus sp. 17376].	29.46	404	242	7	38	434	232	599	6e-46	179
rs:WP_029309062	DNA topoisomerase [Cupriavidus metallidurans].	32.86	426	238	12	28	429	252	653	6e-46	181
rs:WP_005934783	DNA topoisomerase III [Faecalibacterium prausnitzii].	32.43	407	244	11	47	445	235	618	6e-46	179
rs:WP_025481759	DNA topoisomerase [Enterococcus faecium].	31.78	409	237	15	61	454	43	424	6e-46	177
rs:WP_035604997	DNA topoisomerase III [Haloferula sp. BvORR071].	33.91	404	231	13	40	426	263	647	6e-46	181
rs:WP_015395978	DNA topoisomerase III [Candidatus Kinetoplastibacterium desouzaii].	31.03	390	242	8	24	399	237	613	6e-46	180
rs:WP_044427394	DNA topoisomerase III [Skermanella aerolata].	33.42	368	215	10	40	385	232	591	6e-46	180
rs:WP_023598157	DNA topoisomerase III [Pandoraea pnomenusa].	34.30	344	204	10	55	385	270	604	6e-46	181
rs:WP_034705127	DNA topoisomerase III [Chryseobacterium luteum].	34.15	366	232	9	40	402	233	592	6e-46	179
rs:WP_016097322	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.05	406	262	12	57	454	267	658	6e-46	179
rs:WP_000838494	DNA topoisomerase III [Staphylococcus aureus].	29.01	424	269	9	35	450	227	626	6e-46	179
rs:WP_033578745	DNA topoisomerase III [Bacillus aryabhattai].	31.29	441	258	14	36	453	244	662	6e-46	179
tr:L7TZD2_MYXSD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.46	382	233	7	43	402	294	672	6e-46	183
rs:WP_026584089	DNA topoisomerase III [Bacillus sp. J33].	29.71	414	254	8	36	446	230	609	6e-46	179
rs:WP_033859118	DNA topoisomerase 3 [Staphylococcus aureus].	29.01	424	269	9	35	450	227	626	6e-46	179
rs:WP_016200501	DNA topoisomerase III [Elizabethkingia meningoseptica].	31.99	447	269	14	22	449	216	646	6e-46	179
rs:WP_044278434	ATP-dependent DNA helicase RecQ [Myxococcus stipitatus].	32.46	382	233	7	43	402	289	667	7e-46	183
sp:TOP3_STAS1	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	29.67	418	259	9	43	450	235	627	7e-46	179
rs:WP_025809633	DNA topoisomerase III [Bacillus licheniformis].	31.72	413	243	16	47	452	242	622	7e-46	180
tr:A0A097NA41_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.30	344	204	10	55	385	270	604	7e-46	181
rs:WP_033869006	DNA topoisomerase III, partial [Staphylococcus aureus].	28.77	424	270	9	35	450	106	505	7e-46	178
tr:G5GB63_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	32.40	358	232	6	54	406	309	661	7e-46	179
rs:WP_014430656	DNA topoisomerase III [Rubrivivax gelatinosus].	33.33	405	233	11	40	425	263	649	7e-46	181
rs:WP_036685598	DNA topoisomerase III [Paenibacillus sp. MSt1].	32.03	409	239	9	38	435	234	614	7e-46	179
rs:WP_004342332	DNA topoisomerase III [Prevotella buccae].	30.63	395	257	8	24	406	217	606	7e-46	179
rs:WP_039117708	DNA topoisomerase III [Flavobacterium sp. JRM].	30.05	426	259	13	38	446	231	634	7e-46	179
rs:WP_046060633	DNA topoisomerase III [Acidovorax citrulli].	33.61	366	224	8	47	400	271	629	7e-46	181
rs:WP_046710691	ATP-dependent DNA helicase RecQ [Myxococcus fulvus].	33.33	402	232	10	43	416	289	682	7e-46	183
rs:WP_038810986	DNA topoisomerase [Enterococcus faecium].	32.27	409	235	15	61	454	165	546	7e-46	179
tr:C3GTB4_BACTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.31	412	249	12	57	454	273	664	7e-46	179
rs:WP_002482608	DNA topoisomerase III [Staphylococcus saprophyticus].	29.67	418	259	9	43	450	235	627	7e-46	179
rs:WP_002316086	DNA topoisomerase [Enterococcus faecium].	32.03	409	236	15	61	454	165	546	7e-46	179
rs:WP_038206454	DNA topoisomerase III [Xenophilus azovorans].	31.91	376	231	10	40	400	271	636	7e-46	181
rs:WP_043816567	DNA topoisomerase III [Rubrivivax gelatinosus].	34.52	365	205	10	40	385	263	612	7e-46	180
rs:WP_018005000	DNA topoisomerase III [Cupriavidus taiwanensis].	32.58	356	221	7	38	385	253	597	8e-46	181
rs:WP_010681314	DNA topoisomerase [Acetivibrio cellulolyticus].	30.83	373	237	10	40	399	271	635	8e-46	179
tr:G0F0R0_CUPNN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.87	356	220	7	38	385	217	561	8e-46	180
rs:WP_001094104	DNA topoisomerase III [Bacillus cereus].	29.98	407	261	11	57	454	267	658	8e-46	179
rs:WP_006566731	DNA topoisomerase III [Anaerostipes caccae].	30.22	407	251	6	24	428	224	599	8e-46	179
rs:WP_047775577	DNA topoisomerase III [Flavobacterium sp. ABG].	30.05	436	267	14	38	456	231	645	8e-46	179
rs:WP_015914564	DNA topoisomerase III [Acidovorax ebreus].	33.80	361	218	9	53	400	276	628	8e-46	181
rs:WP_001840612	DNA topoisomerase III, partial [Salmonella enterica].	36.36	264	160	3	122	385	1	256	8e-46	172
rs:WP_021375833	DNA topoisomerase III family protein [Peptoclostridium difficile].	30.03	393	236	6	48	435	248	606	8e-46	179
tr:D1AS14_SEBTE	SubName: Full=DNA topoisomerase type IA central domain protein {ECO:0000313|EMBL:ACZ11001.1};	30.91	453	271	12	24	459	228	655	8e-46	179
rs:WP_038502539	DNA topoisomerase III [Achromobacter xylosoxidans].	35.26	363	204	9	38	385	252	598	8e-46	180
rs:WP_015402308	DNA topoisomerase III [Desulfocapsa sulfexigens].	32.08	371	224	10	40	399	261	614	8e-46	180
rs:WP_003386221	DNA topoisomerase III [Brevibacillus borstelensis].	30.40	454	279	13	18	450	220	657	8e-46	179
tr:U2KVD6_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.91	398	254	9	37	428	30	416	8e-46	177
rs:WP_020925716	DNA topoisomerase III [Achromobacter xylosoxidans].	35.26	363	204	9	38	385	252	598	8e-46	180
rs:WP_011807073	DNA topoisomerase III [Acidovorax sp. JS42].	33.80	361	218	9	53	400	276	628	8e-46	181
rs:WP_018753683	DNA topoisomerase III [Paenibacillus sanguinis].	32.67	401	236	7	34	428	229	601	8e-46	179
rs:WP_014202755	DNA topoisomerase III [Owenweeksia hongkongensis].	31.13	363	241	7	36	396	229	584	8e-46	179
rs:WP_000838486	DNA topoisomerase 3 [Staphylococcus aureus].	29.18	425	267	11	35	450	227	626	8e-46	179
rs:WP_031907119	DNA topoisomerase III [Staphylococcus aureus].	29.18	425	267	11	35	450	227	626	8e-46	179
rs:WP_032548386	DNA topoisomerase, partial [Peptoclostridium difficile].	32.37	414	248	10	52	452	196	590	9e-46	179
rs:WP_006389468	DNA topoisomerase III [Achromobacter xylosoxidans].	35.26	363	204	9	38	385	252	598	9e-46	180
tr:I6H4J4_SHIFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	39.73	219	124	3	89	307	1	211	9e-46	170
rs:WP_028884328	DNA topoisomerase III [Taylorella asinigenitalis].	32.22	360	217	7	38	385	253	597	9e-46	180
rs:WP_024566950	DNA topoisomerase III [Elizabethkingia anophelis].	31.97	441	276	12	22	459	216	635	9e-46	179
rs:WP_033645481	DNA topoisomerase, partial [Enterococcus faecium].	32.37	414	248	10	52	452	153	547	9e-46	178
rs:WP_042775764	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	32.48	314	199	2	35	340	245	553	9e-46	178
rs:WP_042566347	DNA topoisomerase III [Flavobacterium sp. MEB061].	31.23	365	236	8	38	401	231	581	9e-46	179
rs:WP_010494059	DNA topoisomerase III [Paenibacillus elgii].	32.44	410	236	11	38	435	234	614	9e-46	179
rs:WP_008396829	DNA topoisomerase III [Clostridium sp. M62/1].	31.94	407	246	11	47	445	235	618	9e-46	179
rs:WP_032581749	DNA topoisomerase III [Bacteroides fragilis].	32.67	352	223	9	49	396	268	609	9e-46	179
rs:WP_033861666	DNA topoisomerase III, partial [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	9e-46	179
rs:WP_009334925	DNA topoisomerase III [Bacillus sp. 2_A_57_CT2].	28.60	437	267	9	18	446	210	609	9e-46	179
rs:WP_005802239	DNA topoisomerase III [Bacteroides fragilis].	32.67	352	223	9	49	396	268	609	9e-46	179
rs:WP_024984278	DNA topoisomerase III [Brevibacillus borstelensis].	30.40	454	279	13	18	450	220	657	9e-46	179
rs:WP_031874900	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	9e-46	179
rs:WP_018357668	DNA topoisomerase III [Porphyromonas levii].	34.16	363	229	8	37	396	232	587	9e-46	178
rs:WP_008657518	MULTISPECIES: DNA topoisomerase III [Bacteroides].	32.67	352	223	9	49	396	268	609	9e-46	179
rs:WP_022348346	DNA topoisomerase III [Bacteroides fragilis].	32.67	352	223	9	49	396	268	609	9e-46	179
rs:WP_025161293	DNA topoisomerase III [[Clostridium] bifermentans].	29.02	386	238	6	47	428	244	597	1e-45	179
rs:WP_021897294	DNA topoisomerase III [Prevotella sp. CAG:924].	33.64	434	239	16	18	414	212	633	1e-45	179
rs:WP_041060515	DNA topoisomerase III [Jeotgalibacillus campisalis].	32.23	394	237	12	74	456	283	657	1e-45	179
rs:WP_032565346	DNA topoisomerase III [Bacteroides fragilis].	32.67	352	223	9	49	396	268	609	1e-45	179
rs:WP_032593454	DNA topoisomerase III [Bacteroides fragilis].	32.67	352	223	9	49	396	268	609	1e-45	179
rs:WP_033616825	MULTISPECIES: DNA topoisomerase, partial [Enterococcus].	32.45	416	245	11	52	452	40	434	1e-45	176
rs:WP_041228250	DNA topoisomerase III [Cupriavidus necator].	30.48	420	260	9	38	436	253	661	1e-45	180
rs:WP_035817413	DNA topoisomerase III [Cupriavidus sp. SK-4].	30.48	420	260	9	38	436	253	661	1e-45	180
rs:WP_018910169	DNA topoisomerase III [Prevotella veroralis].	32.54	378	228	11	18	375	216	586	1e-45	178
rs:WP_008769960	DNA topoisomerase III [Bacteroides sp. 2_1_16].	32.67	352	223	9	49	396	268	609	1e-45	179
rs:WP_032529132	DNA topoisomerase III [Bacteroides fragilis].	32.67	352	223	9	49	396	268	609	1e-45	179
rs:WP_035765999	DNA topoisomerase [Butyrivibrio sp. NC2002].	30.94	446	253	14	47	454	270	698	1e-45	181
tr:R8CJY7_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.54	409	252	12	57	454	267	658	1e-45	179
rs:WP_032563483	DNA topoisomerase III [Bacteroides fragilis].	32.67	352	223	9	49	396	268	609	1e-45	179
rs:WP_022537063	DNA topoisomerase III [Ralstonia pickettii].	30.48	420	260	9	38	436	253	661	1e-45	180
rs:WP_017225403	DNA topoisomerase III [Cupriavidus basilensis].	32.16	398	244	10	38	426	253	633	1e-45	180
rs:WP_031838445	DNA topoisomerase III, partial [Staphylococcus aureus].	28.77	424	270	9	35	450	129	528	1e-45	178
rs:WP_010993481	DNA topoisomerase III [Bacteroides fragilis].	32.67	352	223	9	49	396	268	609	1e-45	179
tr:A0A015X0P0_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EXZ04049.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EXZ04049.1};	32.67	352	223	9	49	396	258	599	1e-45	179
rs:WP_004570515	DNA topoisomerase III [Polaribacter irgensii].	30.31	386	257	8	18	402	212	586	1e-45	179
tr:U5JDV2_PEPDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.37	414	248	10	52	452	194	588	1e-45	178
rs:WP_011485578	DNA topoisomerase III [Polaromonas sp. JS666].	32.33	365	230	6	47	400	272	630	1e-45	181
rs:WP_031897507	DNA topoisomerase III, partial [Staphylococcus aureus].	28.77	424	270	9	35	450	145	544	1e-45	178
rs:WP_026729058	DNA topoisomerase III [Flavobacterium denitrificans].	32.05	365	233	8	38	401	231	581	1e-45	179
tr:A0A0E2SUF0_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EXZ76979.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EXZ76979.1};	32.67	352	223	9	49	396	258	599	1e-45	179
tr:E4ICB9_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.37	414	248	10	52	452	162	556	1e-45	178
rs:WP_035234409	hypothetical protein, partial [Desulfobulbus sp. Tol-SR].	30.92	401	251	8	47	446	245	620	1e-45	179
rs:WP_045167716	DNA topoisomerase III [Prevotella intermedia].	30.95	391	249	11	18	397	217	597	1e-45	178
rs:WP_016215923	DNA topoisomerase III [Eubacterium sp. 14-2].	32.87	362	227	4	50	396	245	605	1e-45	179
rs:WP_031775289	DNA topoisomerase 3 [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	1e-45	179
sp:TOP3_STAAB	RecName: Full=Putative DNA topoisomerase 3; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	29.01	424	269	9	35	450	227	626	1e-45	179
rs:WP_016090159	DNA topoisomerase III [Bacillus cereus].	30.22	407	260	11	57	454	267	658	1e-45	179
rs:WP_003072146	DNA topoisomerase III [Comamonas testosteroni].	34.41	372	225	8	40	399	263	627	1e-45	181
tr:N1ZTU5_9FIRM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EMZ19346.1};	31.90	420	250	11	40	445	96	493	1e-45	177
rs:WP_025991918	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	34.66	277	173	3	23	295	184	456	1e-45	176
rs:WP_029044368	DNA topoisomerase III [Cupriavidus sp. WS].	31.33	399	246	9	38	426	253	633	1e-45	180
rs:WP_022252283	DNA topoisomerase III [Prevotella sp. CAG:386].	29.52	420	259	11	18	406	212	625	1e-45	179
rs:WP_033851494	DNA topoisomerase III, partial [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	1e-45	179
rs:WP_001996279	DNA topoisomerase III [Bacillus cereus].	30.56	409	256	12	57	454	268	659	1e-45	179
rs:WP_025154735	hypothetical protein [Morganella morganii].	28.94	425	279	6	19	429	227	642	1e-45	179
tr:A0A0E2RW48_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EXZ52234.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EXZ52234.1};	32.67	352	223	9	49	396	258	599	1e-45	179
rs:WP_036871357	DNA topoisomerase III [Prevotella histicola].	31.50	400	241	10	24	396	221	614	1e-45	178
rs:WP_000838501	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	1e-45	179
rs:WP_000838500	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	1e-45	179
rs:WP_032537565	DNA topoisomerase III [Bacteroides fragilis].	33.14	350	224	8	49	396	268	609	1e-45	179
rs:WP_047445092	DNA topoisomerase III [Alistipes sp. ZOR0009].	32.42	364	238	7	37	399	230	586	1e-45	179
rs:WP_040468959	DNA topoisomerase III, partial [Eubacterium plexicaudatum].	32.14	420	249	11	40	445	127	524	1e-45	178
rs:WP_032517984	DNA topoisomerase, partial [Peptoclostridium difficile].	32.37	414	248	10	52	452	196	590	1e-45	178
rs:WP_010105941	DNA topoisomerase III [Verminephrobacter aporrectodeae].	33.05	357	224	7	54	400	276	627	1e-45	181
rs:WP_031904145	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	1e-45	179
rs:WP_035663412	DNA topoisomerase III [Bacillus akibai].	33.24	343	216	6	60	396	258	593	1e-45	179
rs:WP_038501299	DNA topoisomerase III [Basilea psittacipulmonis].	31.03	377	232	8	22	385	237	598	1e-45	179
rs:WP_045372352	DNA topoisomerase III [Jejuia pallidilutea].	29.86	432	269	12	38	454	231	643	1e-45	179
rs:WP_026781568	DNA topoisomerase III [Polaromonas sp. EUR3 1.2.1].	32.31	390	242	8	26	400	248	630	1e-45	181
rs:WP_040239386	DNA topoisomerase III, partial [Klebsiella pneumoniae].	33.80	355	218	5	27	367	173	524	1e-45	177
rs:WP_010783371	DNA topoisomerase III, partial [Enterococcus faecalis].	31.82	418	245	11	52	452	76	470	1e-45	177
rs:WP_022328708	DNA topoisomerase III [Prevotella sp. CAG:732].	29.47	475	268	15	37	454	230	694	1e-45	178
rs:WP_039407184	DNA topoisomerase III [Pandoraea pulmonicola].	32.99	385	233	11	55	426	270	642	1e-45	180
rs:WP_031868422	DNA topoisomerase III, partial [Staphylococcus aureus].	28.77	424	270	9	35	450	196	595	1e-45	178
rs:WP_031911917	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	1e-45	178
rs:WP_007593005	DNA topoisomerase III [Lachnoanaerobaculum sp. OBRC5-5].	31.94	407	246	11	47	445	235	618	1e-45	178
rs:WP_016428507	DNA topoisomerase III [Paenisporosarcina sp. HGH0030].	31.05	438	256	12	35	456	248	655	1e-45	178
tr:A0A0C5J2H9_9RHOO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.47	394	244	9	40	425	260	635	1e-45	180
rs:WP_043350930	DNA topoisomerase III [Cupriavidus basilensis].	31.74	397	247	8	38	426	253	633	1e-45	180
rs:WP_021286089	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	1e-45	178
rs:WP_031834541	DNA topoisomerase III, partial [Staphylococcus aureus].	28.77	424	270	9	35	450	197	596	1e-45	178
rs:WP_040036331	DNA topoisomerase III [Bacillaceae bacterium MTCC 10057].	29.49	434	266	11	36	450	244	656	1e-45	178
rs:WP_031789086	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	1e-45	178
rs:WP_021430807	DNA topoisomerase III family protein [[Clostridium] bifermentans].	28.94	387	237	7	47	428	244	597	1e-45	178
rs:WP_045289425	DNA topoisomerase III [Bacillus aryabhattai].	31.52	441	257	14	36	453	244	662	1e-45	178
rs:WP_005790880	DNA topoisomerase III [Bacteroides fragilis].	32.67	352	223	9	49	396	268	609	1e-45	178
rs:WP_031911617	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	1e-45	178
rs:WP_031795285	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	1e-45	178
rs:WP_034110802	DNA topoisomerase III, partial [Comamonadaceae bacterium BICA1-1].	35.14	350	200	11	54	385	283	623	1e-45	180
tr:R3UNR0_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.97	391	230	11	77	452	2	371	1e-45	175
rs:WP_039107208	DNA topoisomerase III [Flavobacterium sp. AED].	29.79	423	264	12	38	446	231	634	1e-45	179
rs:WP_031900030	DNA topoisomerase III, partial [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	1e-45	178
rs:WP_044992660	DNA topoisomerase III [Clostridium sp. ATCC 29733].	31.72	413	251	11	27	425	214	609	1e-45	178
rs:WP_031870002	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_031861717	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_035286737	DNA topoisomerase III, partial [Brevibacillus massiliensis].	32.87	359	218	8	36	385	244	588	2e-45	178
rs:WP_044063820	DNA topoisomerase III [Prevotella saccharolytica].	31.28	390	251	9	21	402	214	594	2e-45	178
rs:WP_000838508	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_031863365	DNA topoisomerase III, partial [Staphylococcus aureus].	28.77	424	270	9	35	450	183	582	2e-45	178
rs:WP_031893696	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_031882918	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_034750284	DNA topoisomerase III [Chryseobacterium vrystaatense].	35.06	348	217	9	40	384	233	574	2e-45	178
rs:WP_010733726	MULTISPECIES: DNA topoisomerase III, partial [Enterococcus].	32.12	411	247	10	52	449	120	511	2e-45	176
rs:WP_000838488	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_000838491	DNA topoisomerase 3 [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_031807777	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_025752003	DNA topoisomerase III [Bacillus flexus].	31.52	441	257	14	36	453	244	662	2e-45	178
rs:WP_004083334	DNA topoisomerase III [Clostridium sp. ASF502].	31.90	420	250	11	40	445	228	625	2e-45	178
rs:WP_031901836	DNA topoisomerase 3 [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_031913504	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_032533840	DNA topoisomerase III [Bacteroides fragilis].	32.67	352	223	9	49	396	268	609	2e-45	178
rs:WP_031906579	DNA topoisomerase 3 [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_031902343	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_034558194	DNA topoisomerase, partial [Carnobacterium gallinarum].	32.13	414	249	10	52	452	148	542	2e-45	177
tr:L1NI24_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.28	390	251	9	21	402	236	616	2e-45	178
rs:WP_005817457	DNA topoisomerase III [Bacteroides fragilis].	32.67	352	223	9	49	396	268	609	2e-45	178
rs:WP_032561755	DNA topoisomerase III [Bacteroides fragilis].	32.67	352	223	9	49	396	268	609	2e-45	178
rs:WP_031911155	DNA topoisomerase 3 [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_033859739	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_031911198	DNA topoisomerase III [Staphylococcus aureus].	28.30	424	272	8	35	450	227	626	2e-45	178
rs:WP_031901756	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_031811521	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_047449608	DNA topoisomerase III [Staphylococcus aureus].	29.36	419	274	8	35	450	227	626	2e-45	178
rs:WP_000838489	DNA topoisomerase 3 [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_005798157	DNA topoisomerase III [Bacteroides fragilis].	32.67	352	223	9	49	396	268	609	2e-45	178
rs:WP_003060036	DNA topoisomerase III [Comamonas testosteroni].	34.41	372	225	8	40	399	263	627	2e-45	180
rs:WP_045178387	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_031866479	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_031865861	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_000838490	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
sp:TOP3_STAA3	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_029714564	DNA topoisomerase III [Bacillus sp. JGI 001006-L10].	31.52	441	257	14	36	453	244	662	2e-45	178
rs:WP_004346762	DNA topoisomerase III [Prevotella buccae].	30.38	395	258	8	24	406	217	606	2e-45	178
rs:WP_040296029	DNA topoisomerase III [Barnesiella intestinihominis].	30.93	375	242	8	37	407	230	591	2e-45	178
rs:WP_031833533	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_031925301	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_031921997	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_048510089	DNA topoisomerase III [Chryseobacterium sp. FH2].	34.58	347	220	7	40	384	233	574	2e-45	178
rs:WP_031793812	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_019561538	DNA topoisomerase III [Caldimonas manganoxidans].	32.79	366	212	10	54	400	278	628	2e-45	179
rs:WP_044731338	DNA topoisomerase III [Geobacillus kaustophilus].	30.47	407	248	7	40	445	234	606	2e-45	178
rs:WP_035619101	DNA topoisomerase III [Flavobacterium hydatis].	31.23	365	236	8	38	401	231	581	2e-45	178
rs:WP_001549680	DNA topoisomerase 3 [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_022210148	DNA topoisomerase III [Bacteroides cellulosilyticus CAG:158].	30.27	370	246	8	29	396	258	617	2e-45	178
rs:WP_037305170	hypothetical protein [Ruminococcus albus].	30.00	410	260	7	47	449	216	605	2e-45	178
rs:WP_043375951	DNA topoisomerase III [Comamonas testosteroni].	34.41	372	225	8	40	399	263	627	2e-45	180
rs:WP_031928915	DNA topoisomerase III [Staphylococcus aureus].	28.54	424	271	9	35	450	227	626	2e-45	178
rs:WP_000838475	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_023914047	DNA topoisomerase 3 [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_023627631	hypothetical protein [Bacillus sp. 17376].	29.56	433	271	9	38	453	245	660	2e-45	178
rs:WP_022085420	DNA topoisomerase [Roseburia sp. CAG:197].	30.02	453	256	11	47	446	178	622	2e-45	181
rs:WP_035023683	DNA topoisomerase, partial [Enterococcus villorum].	32.20	413	244	11	52	449	40	431	2e-45	174
rs:WP_043003296	DNA topoisomerase III [Comamonas testosteroni].	34.41	372	225	8	40	399	263	627	2e-45	180
rs:WP_041647890	hypothetical protein, partial [Aromatoleum aromaticum].	32.56	344	206	6	36	371	237	562	2e-45	177
rs:WP_020977494	DNA topoisomerase 3 [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_036930306	DNA topoisomerase III [Prevotella sp. 10(H)].	36.47	340	201	10	70	401	260	592	2e-45	178
tr:U2EZI4_CLOS4	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.72	413	251	11	27	425	216	611	2e-45	178
rs:WP_047375879	DNA topoisomerase III [Exiguobacterium sp. ZOR0005].	31.60	424	250	12	47	452	255	656	2e-45	178
rs:WP_031890145	DNA topoisomerase 3 [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_000838473	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_031785230	DNA topoisomerase 3 [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
tr:K0WYG1_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJZ64257.1};	30.93	375	242	8	37	407	260	621	2e-45	178
tr:U2QF86_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.78	409	237	15	61	454	165	546	2e-45	177
rs:WP_033606902	DNA topoisomerase, partial [Enterococcus faecium].	32.13	414	249	10	52	452	148	542	2e-45	177
rs:WP_000838487	DNA topoisomerase 3 [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_044290852	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_002352589	MULTISPECIES: DNA topoisomerase [Enterococcus].	32.37	414	248	10	52	452	264	658	2e-45	178
tr:R2S4C9_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.87	411	248	10	52	449	45	436	2e-45	174
rs:WP_047498649	DNA topoisomerase III, partial [Methylibium sp. CF059].	32.98	379	220	10	40	399	259	622	2e-45	179
rs:WP_006556993	DNA topoisomerase III [Veillonella ratti].	28.54	466	263	12	47	455	256	708	2e-45	178
rs:WP_032489173	type I topoisomerase [Enterococcus faecalis].	32.37	414	248	10	52	452	264	658	2e-45	178
rs:WP_005657222	DNA topoisomerase III [Bacteroides stercoris].	32.61	371	236	9	30	396	257	617	2e-45	178
rs:WP_000838482	DNA topoisomerase 3 [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_035116511	DNA topoisomerase III [Clostridium sp. NCR].	28.94	387	237	7	47	428	244	597	2e-45	178
tr:K1FRK7_BACFG	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKA80127.1};	33.14	350	224	8	49	396	292	633	2e-45	178
rs:WP_031910301	DNA topoisomerase III, partial [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_000838484	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_043711949	topoisomerase I [Weissella cibaria].	30.73	449	271	15	24	446	232	666	2e-45	178
tr:W7DUD1_9LIST	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	33.24	370	219	7	38	399	231	580	2e-45	178
rs:WP_034264488	DNA topoisomerase III [Bacillus sp. Aph1].	31.07	441	259	14	36	453	244	662	2e-45	178
rs:WP_006190863	DNA topoisomerase 3 [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_046290345	DNA topoisomerase III [Pandoraea oxalativorans].	33.72	341	210	8	55	385	270	604	2e-45	179
rs:WP_040473791	DNA topoisomerase III [Flavobacterium frigoris].	30.14	418	269	10	38	446	231	634	2e-45	178
rs:WP_044960767	DNA topoisomerase III [Faecalibacterium prausnitzii].	31.65	436	255	13	27	445	217	626	2e-45	178
rs:WP_031832724	DNA topoisomerase 3 [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_031234877	DNA topoisomerase III, partial [Salmonella enterica].	29.61	331	223	3	78	400	1	329	2e-45	172
rs:WP_000838506	DNA topoisomerase 3 [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
rs:WP_021932094	DNA topoisomerase III [Tannerella sp. CAG:118].	31.88	367	239	8	37	399	230	589	2e-45	178
rs:WP_021996258	DNA topoisomerase [Clostridium sp. CAG:780].	30.30	406	250	13	22	398	245	646	2e-45	177
rs:WP_026191728	DNA topoisomerase III [Methylosinus sp. LW4].	34.68	372	209	13	37	385	229	589	2e-45	178
rs:WP_024994449	DNA topoisomerase III [Bacteroides paurosaccharolyticus].	31.48	378	243	9	47	417	264	632	2e-45	178
rs:WP_024371561	DNA topoisomerase III [Exiguobacterium sp. 8-11-1].	31.60	424	250	12	47	452	255	656	2e-45	178
rs:WP_031796011	DNA topoisomerase 3 [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-45	178
tr:Q5NX65_AROAE	SubName: Full=TopA protein {ECO:0000313|EMBL:CAI10349.1};	30.83	386	239	7	36	411	237	604	2e-45	177
rs:WP_019413664	hypothetical protein [Paenisporosarcina sp. TG20].	31.95	410	245	13	58	454	265	653	2e-45	178
rs:WP_028889542	DNA topoisomerase III [Tenacibaculum ovolyticum].	30.44	427	274	12	38	454	231	644	2e-45	178
rs:WP_009435078	DNA topoisomerase III [Prevotella sp. oral taxon 306].	32.08	399	244	11	18	396	216	607	2e-45	177
rs:WP_041845987	DNA topoisomerase III [Bacillus thermoamylovorans].	29.27	427	270	9	35	446	243	652	2e-45	178
rs:WP_002198656	DNA topoisomerase III [Bacillus cereus].	30.07	409	258	11	57	454	267	658	2e-45	178
tr:A8SHN5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.65	436	255	13	27	445	219	628	2e-45	178
tr:E6UKV8_RUMA7	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.00	410	260	7	47	449	222	611	2e-45	177
rs:WP_025790876	DNA topoisomerase III [Prevotella histicola].	31.25	400	242	10	24	396	221	614	2e-45	177
rs:WP_035649018	DNA topoisomerase III [Flavobacterium sp. Fl].	32.05	365	233	8	38	401	231	581	2e-45	178
rs:WP_014022468	DNA topoisomerase III [Cyclobacterium marinum].	30.56	360	236	7	38	396	231	577	2e-45	178
rs:WP_035038491	DNA topoisomerase III [Aquabacterium sp. NJ1].	33.88	366	208	10	54	399	289	640	2e-45	179
rs:WP_007484229	DNA topoisomerase III [Bacteroides nordii].	32.49	357	231	8	47	401	266	614	2e-45	178
rs:WP_025866525	DNA topoisomerase III [Bacteroides nordii].	32.49	357	231	8	47	401	266	614	3e-45	178
rs:WP_043040358	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	3e-45	178
rs:WP_000838496	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	3e-45	178
rs:WP_042457656	DNA topoisomerase III [Bacillus sp. FF4].	30.25	433	260	12	35	446	243	654	3e-45	178
rs:WP_047211640	DNA topoisomerase III [Staphylococcus aureus].	28.54	424	271	9	35	450	227	626	3e-45	177
tr:A0A024FL16_9FLAO	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.91	351	220	8	38	385	221	555	3e-45	178
tr:G4BEE6_AGGAP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	37.61	234	137	4	36	268	253	478	3e-45	176
tr:H7FRM8_9FLAO	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.14	418	269	10	38	446	240	643	3e-45	178
rs:WP_028504491	hypothetical protein [Ruminococcus albus].	30.00	410	260	7	47	449	234	623	3e-45	177
rs:WP_045474264	DNA topoisomerase III [Winogradskyella sp. PG-2].	31.91	351	220	8	38	385	231	565	3e-45	178
rs:WP_047968892	DNA topoisomerase III [Bacillus sp. LL01].	30.88	353	236	5	36	385	244	591	3e-45	178
rs:WP_046524222	DNA topoisomerase III [Bacillus sp. SA2-6].	29.63	432	270	11	36	450	244	658	3e-45	177
rs:WP_022257932	DNA topoisomerase [Clostridium sp. CAG:508].	30.63	395	253	11	22	398	245	636	3e-45	177
tr:W7ZEP5_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.03	409	252	12	61	459	253	645	3e-45	177
rs:WP_008271225	MULTISPECIES: DNA topoisomerase [Enterococcus].	31.78	409	237	15	61	454	165	546	3e-45	177
rs:WP_005781365	DNA topoisomerase III [Bacteroides fragilis].	33.14	350	224	8	49	396	268	609	3e-45	177
rs:WP_032537012	MULTISPECIES: DNA topoisomerase III [Bacteroides].	33.14	350	224	8	49	396	268	609	3e-45	177
rs:WP_004632114	DNA topoisomerase III [Gemella morbillorum].	30.99	384	233	9	73	451	263	619	3e-45	177
rs:WP_007856244	DNA topoisomerase III [Bacteroides dorei].	31.52	368	230	10	41	396	264	621	3e-45	177
rs:WP_008674864	DNA topoisomerase III [Bacteroides sp. 9_1_42FAA].	31.52	368	230	10	41	396	264	621	3e-45	177
rs:WP_032941057	DNA topoisomerase III [Bacteroides sp. 3_1_33FAA].	31.52	368	230	10	41	396	264	621	3e-45	177
rs:WP_031797387	DNA topoisomerase III [Staphylococcus aureus].	29.18	425	267	10	35	450	227	626	3e-45	177
rs:WP_016661811	DNA topoisomerase III [Bacteroides stercoris].	32.61	371	236	9	30	396	257	617	3e-45	177
rs:WP_007836205	DNA topoisomerase III [Bacteroides dorei].	31.52	368	230	10	41	396	264	621	3e-45	177
rs:WP_031763953	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	3e-45	177
rs:WP_007840712	DNA topoisomerase III [Bacteroides dorei].	31.52	368	230	10	41	396	264	621	3e-45	177
rs:WP_016228891	hypothetical protein [Lachnospiraceae bacterium 10-1].	29.85	412	252	11	40	446	123	502	3e-45	176
rs:WP_044394496	DNA topoisomerase III [Bacillus subterraneus].	28.94	432	252	10	38	457	232	620	3e-45	177
tr:K1G861_BACFG	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKA90429.1};	33.14	350	224	8	49	396	292	633	3e-45	177
rs:WP_039394586	DNA topoisomerase III [Pandoraea sputorum].	33.72	341	210	8	55	385	270	604	3e-45	179
rs:WP_038605690	DNA topoisomerase III [Bacteroides dorei].	31.52	368	230	10	41	396	264	621	3e-45	177
rs:WP_015480086	DNA topoisomerase III [Polaribacter sp. MED152].	31.25	368	242	8	38	404	231	588	3e-45	178
rs:WP_002384820	type 1 topoisomerase [Enterococcus faecalis].	32.21	416	246	11	52	452	10	404	3e-45	174
rs:WP_000838483	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	3e-45	177
rs:WP_011112497	DNA topoisomerase III [Nitrosomonas europaea].	31.45	407	250	12	40	435	255	643	3e-45	178
rs:WP_035587590	DNA topoisomerase III [Elizabethkingia anophelis].	31.97	441	276	12	22	459	216	635	3e-45	177
rs:WP_033714660	DNA topoisomerase III, partial [Bacillus cereus].	31.11	405	251	12	57	450	72	459	3e-45	176
rs:WP_047551258	DNA topoisomerase III [Staphylococcus aureus].	29.36	419	274	8	35	450	227	626	3e-45	177
rs:WP_021956985	DNA topoisomerase [Eubacterium sp. CAG:115].	28.74	414	278	5	36	447	226	624	3e-45	177
rs:WP_002559428	DNA topoisomerase III [Bacteroides sp. HPS0048].	32.49	357	231	8	47	401	266	614	3e-45	177
rs:WP_022219532	DNA topoisomerase III [Bacteroides clarus CAG:160].	32.08	371	238	9	30	396	257	617	3e-45	177
rs:WP_009229076	DNA topoisomerase III [Prevotella sp. oral taxon 299].	31.50	381	248	9	37	411	230	603	3e-45	177
rs:WP_007207501	DNA topoisomerase III [Enterococcus italicus].	29.57	399	242	6	47	445	241	600	3e-45	177
rs:WP_031644658	DNA topoisomerase [Listeria monocytogenes].	32.13	414	249	10	52	452	264	658	3e-45	177
rs:WP_013617264	DNA topoisomerase III [Bacteroides salanitronis].	31.51	365	235	9	23	385	248	599	3e-45	177
rs:WP_000838505	DNA topoisomerase 3 [Staphylococcus aureus].	28.54	424	271	9	35	450	227	626	3e-45	177
rs:WP_032331321	DNA topoisomerase III, partial [Escherichia coli].	37.45	235	140	2	151	385	12	239	3e-45	170
tr:D1K925_9BACE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEZ19663.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EEZ19663.1};	31.52	368	230	10	41	396	275	632	3e-45	177
rs:WP_047560259	DNA topoisomerase III [Staphylococcus aureus].	29.36	419	274	8	35	450	227	626	3e-45	177
rs:WP_046938350	DNA topoisomerase III, partial [Xanthomonas perforans].	38.64	295	168	7	38	325	57	345	3e-45	172
rs:WP_041335059	DNA topoisomerase III [Bacillus subtilis].	31.52	387	233	12	45	425	240	600	3e-45	178
rs:WP_046150268	DNA topoisomerase III [Parabacteroides sp. HGS0025].	30.83	373	243	9	37	405	230	591	3e-45	177
rs:WP_047529612	DNA topoisomerase III [Staphylococcus aureus].	29.36	419	274	8	35	450	227	626	3e-45	177
rs:WP_002144421	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	31.11	405	251	12	57	450	267	654	3e-45	177
rs:WP_021196961	MULTISPECIES: DNA topoisomerase III [Ralstonia].	33.08	402	233	12	38	425	253	632	3e-45	179
rs:WP_025719810	DNA topoisomerase III [Paenibacillus polymyxa].	31.58	399	236	9	38	426	233	604	3e-45	177
tr:W7WFD4_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.33	378	222	9	40	400	263	627	3e-45	178
rs:WP_017814627	DNA topoisomerase III [Paenibacillus sp. A9].	29.90	408	253	6	38	435	234	618	3e-45	177
rs:WP_004381796	DNA topoisomerase III [Prevotella veroralis].	32.28	378	229	11	18	375	216	586	3e-45	177
sp:TOP3_STAA8	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	28.94	425	268	11	35	450	227	626	3e-45	177
rs:WP_018574459	hypothetical protein [Oligella ureolytica].	32.97	370	214	10	38	394	253	601	4e-45	179
rs:WP_039597233	DNA topoisomerase III [Ralstonia sp. A12].	34.53	362	204	10	38	385	253	595	4e-45	179
rs:WP_027586242	DNA topoisomerase III [Prolixibacter bellariivorans].	31.08	415	243	14	48	446	251	638	4e-45	177
rs:WP_047426032	DNA topoisomerase III [Staphylococcus aureus].	29.36	419	274	8	35	450	227	626	4e-45	177
rs:WP_002636140	ATP-dependent DNA helicase RecQ [Myxococcus sp. (contaminant ex DSM 436)].	34.32	370	212	9	47	392	295	657	4e-45	181
rs:WP_011810900	DNA topoisomerase III [Verminephrobacter eiseniae].	33.07	381	227	9	40	399	262	635	4e-45	179
rs:WP_036730954	DNA topoisomerase III [Paenibacillus sp. FSL R7-277].	31.13	408	244	9	38	435	233	613	4e-45	177
rs:WP_045384455	DNA topoisomerase III, partial [Vibrio campbellii].	34.62	312	188	5	26	328	238	542	4e-45	176
rs:WP_034631803	DNA topoisomerase III [Bacillus okhensis].	30.86	431	256	12	36	446	244	652	4e-45	177
rs:WP_029306833	DNA topoisomerase III [Cupriavidus metallidurans].	32.49	357	221	8	38	385	253	598	4e-45	179
rs:WP_011517984	DNA topoisomerase III [Cupriavidus metallidurans].	32.49	357	221	8	38	385	253	598	4e-45	179
rs:WP_009855757	DNA topoisomerase III [Rubrivivax benzoatilyticus].	34.52	365	205	10	40	385	263	612	4e-45	178
rs:WP_040647948	hypothetical protein [Ruminococcus callidus].	31.91	398	254	9	37	428	229	615	4e-45	177
rs:WP_028908338	DNA topoisomerase III [Prevotella ruminicola].	30.83	386	238	11	24	385	217	597	4e-45	177
rs:WP_038268239	DNA topoisomerase [[Clostridium] litorale].	31.48	432	255	14	30	446	240	645	4e-45	177
rs:WP_021067658	DNA topoisomerase III [Exiguobacterium pavilionensis].	31.84	424	249	12	47	452	255	656	4e-45	177
rs:WP_047451939	DNA topoisomerase III [Chryseobacterium sp. OV715].	34.77	348	218	9	40	384	233	574	4e-45	177
rs:WP_033614632	DNA topoisomerase, partial [Enterococcus faecium].	32.29	415	247	11	52	452	40	434	4e-45	174
rs:WP_038142129	DNA topoisomerase III, partial [Verrucomicrobia bacterium SCGC AAA164-E04].	33.33	372	223	8	40	401	257	613	4e-45	178
tr:V2LGS5_SALET	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESJ51281.1};	37.45	235	140	2	151	385	3	230	4e-45	170
rs:WP_007477853	DNA topoisomerase III [Listeria fleischmannii].	33.70	368	220	9	38	399	231	580	4e-45	177
tr:A0A0D0RIW4_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.37	373	241	5	60	428	249	610	4e-45	177
rs:XP_001786801	predicted protein [Physcomitrella patens].	32.28	316	189	4	34	342	113	410	4e-45	173
tr:C7YE99_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.21	416	246	11	52	452	21	415	4e-45	174
rs:WP_026825790	DNA topoisomerase III [Exiguobacterium marinum].	31.50	419	244	11	47	446	255	649	4e-45	177
rs:WP_013145263	DNA topoisomerase III [Geobacillus sp. C56-T3].	31.99	372	238	7	36	403	245	605	4e-45	177
rs:WP_029463186	DNA topoisomerase III, partial [Comamonadaceae bacterium H1].	34.89	364	210	11	40	385	269	623	4e-45	179
rs:WP_021432698	DNA topoisomerase III family protein [[Clostridium] bifermentans].	29.17	384	234	7	47	425	244	594	4e-45	177
rs:WP_034538694	DNA topoisomerase III [Carnobacterium inhibens].	29.93	411	257	11	56	454	260	651	4e-45	177
rs:WP_045135956	DNA topoisomerase, partial [Enterococcus faecium].	32.13	414	249	10	52	452	155	549	4e-45	176
rs:WP_000838480	DNA topoisomerase III [Staphylococcus aureus].	28.54	424	271	9	35	450	227	626	4e-45	177
rs:WP_017511104	MULTISPECIES: DNA topoisomerase III [Cupriavidus].	32.49	357	221	8	38	385	253	598	5e-45	178
rs:WP_008642749	DNA topoisomerase III [Cupriavidus sp. HMR-1].	32.49	357	221	8	38	385	253	598	5e-45	178
rs:WP_013082807	DNA topoisomerase III [Bacillus megaterium].	31.29	441	258	14	36	453	244	662	5e-45	177
rs:WP_033642401	DNA topoisomerase, partial [Enterococcus faecium].	32.12	411	247	10	52	449	153	544	5e-45	176
tr:A0A0E1RBZ5_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.21	416	246	11	52	452	37	431	5e-45	174
rs:WP_035881171	DNA topoisomerase III [Cupriavidus metallidurans].	32.49	357	221	8	38	385	253	598	5e-45	178
rs:WP_007545235	DNA topoisomerase III, partial [Listeria fleischmannii].	32.97	370	220	7	38	399	72	421	5e-45	176
rs:WP_014299351	DNA topoisomerase III [Bacteroides fragilis].	32.67	352	223	9	49	396	268	609	5e-45	177
rs:WP_006037718	DNA topoisomerase III [Paenibacillus curdlanolyticus].	31.57	396	224	9	18	385	210	586	5e-45	177
rs:WP_024305832	topoisomerase I [Lactobacillus rhamnosus].	30.34	445	272	14	33	454	241	670	5e-45	177
rs:WP_034652787	DNA topoisomerase III [Bacillus megaterium].	31.29	441	258	14	36	453	244	662	5e-45	177
rs:WP_001094105	DNA topoisomerase III [Bacillus cereus].	29.68	411	261	13	55	454	265	658	5e-45	177
tr:J9GKB8_9ZZZZ	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EJX00095.1};	32.29	353	227	9	47	396	266	609	5e-45	177
rs:WP_025074494	DNA topoisomerase III [Bacteroides faecichinchillae].	32.10	352	229	8	47	396	265	608	5e-45	177
rs:WP_036899393	DNA topoisomerase III [Prevotella sp. S7 MS 2].	30.85	389	250	11	18	397	212	590	5e-45	177
rs:WP_021902623	DNA topoisomerase III [Porphyromonas sp. CAG:1061].	32.05	365	236	9	37	396	232	589	5e-45	176
rs:WP_021747342	MULTISPECIES: DNA topoisomerase III [Oscillibacter].	31.94	407	246	11	47	445	235	618	5e-45	177
rs:WP_009224508	DNA topoisomerase III [Paenibacillus sp. oral taxon 786].	32.41	398	243	6	34	428	229	603	5e-45	177
rs:WP_032573824	DNA topoisomerase III [Bacteroides fragilis].	32.67	352	223	9	49	396	268	609	5e-45	177
rs:WP_031795571	DNA topoisomerase III [Staphylococcus aureus].	28.47	425	270	10	35	450	227	626	5e-45	177
tr:S7WTU8_9BACT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EPR70149.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EPR70149.1};	29.29	420	268	10	38	446	166	567	5e-45	177
rs:WP_039830311	DNA topoisomerase III, partial [Pandoraea sp. B-6].	32.03	384	235	10	55	426	270	639	5e-45	178
rs:WP_018029103	hypothetical protein [Porphyromonas somerae].	32.05	365	236	9	37	396	232	589	5e-45	176
rs:WP_015944491	DNA topoisomerase III [Desulfitobacterium hafniense].	32.36	377	238	8	23	393	249	614	5e-45	177
rs:WP_013485776	DNA topoisomerase III [Ethanoligenens harbinense].	32.36	411	229	13	47	445	235	608	5e-45	177
rs:WP_034932201	DNA topoisomerase III [Candidatus Accumulibacter sp. SK-12].	31.86	408	237	10	40	425	255	643	5e-45	178
rs:WP_046460388	DNA topoisomerase III [Comamonas testosteroni].	34.14	372	226	8	40	399	263	627	5e-45	179
rs:WP_017382019	hypothetical protein [Paenisporosarcina sp. TG-14].	31.89	417	236	14	58	454	265	653	6e-45	177
rs:WP_043981980	DNA topoisomerase III [Bacillus aryabhattai].	31.52	441	257	14	36	453	244	662	6e-45	177
rs:WP_010722281	DNA topoisomerase III, partial [Enterococcus faecium].	32.29	415	247	11	52	452	40	434	6e-45	173
rs:WP_016085083	DNA topoisomerase III [Bacillus cereus].	29.98	407	261	12	57	454	267	658	6e-45	177
rs:WP_047937592	DNA topoisomerase [Enterococcus faecium].	33.82	343	201	10	65	400	47	370	6e-45	172
rs:WP_034728006	DNA topoisomerase III [Chryseobacterium sp. JM1].	34.77	348	218	9	40	384	233	574	6e-45	177
rs:WP_003064768	DNA topoisomerase III [Comamonas testosteroni].	34.14	372	226	8	40	399	263	627	6e-45	179
tr:E4IKL2_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.12	411	247	10	52	449	162	553	6e-45	176
rs:WP_019948955	hypothetical protein [Hymenobacter aerophilus].	30.46	453	264	13	30	446	245	682	6e-45	177
rs:WP_015374908	DNA topoisomerase I [Geobacillus sp. GHH01].	31.99	372	238	7	36	403	245	605	6e-45	177
rs:WP_000838497	DNA topoisomerase 3 [Staphylococcus aureus].	28.54	424	271	9	35	450	227	626	6e-45	177
tr:M1P191_DESSD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.55	412	242	10	40	444	227	605	6e-45	176
rs:WP_029550108	DNA topoisomerase III [Staphylococcus aureus].	28.54	424	271	9	35	450	227	626	6e-45	177
rs:WP_023604926	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	6e-45	177
tr:R8QQ81_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.11	405	251	12	57	450	83	470	6e-45	175
rs:WP_028353834	DNA topoisomerase III [Bordetella petrii].	34.99	363	205	9	38	385	252	598	6e-45	178
rs:WP_041079115	DNA topoisomerase III [Staphylococcus saprophyticus].	29.43	418	260	9	43	450	235	627	6e-45	176
rs:WP_046513834	DNA topoisomerase III [Cryomorphaceae bacterium ASP10-05a].	30.27	446	285	13	11	446	205	634	6e-45	177
rs:WP_032806200	topoisomerase I [Oenococcus oeni].	29.35	460	264	14	29	454	237	669	7e-45	176
rs:WP_047193235	DNA topoisomerase III [[Polyangium] brachysporum].	32.09	374	227	9	40	399	264	624	7e-45	177
rs:WP_031905536	DNA topoisomerase 3 [Staphylococcus aureus].	28.54	424	271	9	35	450	227	626	7e-45	176
rs:WP_016270904	DNA topoisomerase III [Bacteroides vulgatus].	31.25	368	231	10	41	396	264	621	7e-45	176
tr:T3QPZ8_PEPDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.29	353	196	7	90	435	2	318	7e-45	172
rs:WP_021322604	MULTISPECIES: DNA topoisomerase III [Geobacillus].	31.99	372	238	7	36	403	245	605	7e-45	176
rs:WP_000838507	DNA topoisomerase III [Staphylococcus aureus].	28.94	425	268	11	35	450	227	626	7e-45	176
rs:WP_024535808	DNA topoisomerase III [Sporosarcina sp. EUR3 2.2.2].	32.20	413	240	11	58	454	265	653	7e-45	176
rs:WP_034777902	DNA topoisomerase III [Exiguobacterium mexicanum].	31.84	424	249	12	47	452	255	656	7e-45	176
rs:WP_002387619	DNA topoisomerase [Enterococcus faecalis].	31.82	418	245	11	52	452	264	658	7e-45	176
rs:WP_029429174	DNA topoisomerase III [Bacteroides cellulosilyticus].	30.27	370	246	8	29	396	258	617	7e-45	177
rs:WP_040208500	MULTISPECIES: DNA topoisomerase III [Bacillus].	28.81	427	272	8	36	446	244	654	7e-45	176
rs:WP_044377079	DNA topoisomerase III, partial [Escherichia coli].	37.71	236	139	3	36	271	251	478	7e-45	174
rs:WP_046472782	DNA topoisomerase III [Staphylococcus aureus].	28.54	424	271	9	35	450	227	626	7e-45	176
rs:WP_016763797	DNA topoisomerase III [Bacillus megaterium].	31.29	441	258	14	36	453	244	662	7e-45	176
rs:WP_016177605	DNA topoisomerase III [Enterococcus durans].	31.88	414	250	10	52	452	264	658	7e-45	176
rs:WP_039232415	DNA topoisomerase III [Bacillus thermotolerans].	29.26	434	267	11	36	450	244	656	7e-45	176
rs:WP_043701074	DNA topoisomerase III, partial [Tepidimonas taiwanensis].	35.99	364	206	12	40	385	275	629	7e-45	177
rs:WP_019686166	DNA topoisomerase III [Paenibacillus polymyxa].	30.75	400	242	8	36	426	231	604	7e-45	176
rs:WP_007210360	DNA topoisomerase III [Bacteroides cellulosilyticus].	30.27	370	246	8	29	396	258	617	7e-45	176
tr:B7U5A8_BACIU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.78	387	232	12	45	425	240	600	7e-45	177
tr:A0A099Y2H8_9FLAO	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.28	403	254	9	38	416	231	626	7e-45	176
rs:WP_016078851	DNA topoisomerase III [Bacillus cereus].	30.22	407	260	12	57	454	267	658	8e-45	176
rs:WP_014195908	MULTISPECIES: DNA topoisomerase III [Geobacillus].	31.99	372	238	7	36	403	245	605	8e-45	176
rs:WP_011965390	DNA topoisomerase III [Bacteroides vulgatus].	31.25	368	231	10	41	396	264	621	8e-45	176
rs:WP_025844431	DNA topoisomerase III [Paenibacillus ehimensis].	31.39	411	241	9	38	435	234	616	8e-45	176
rs:WP_020959943	DNA topoisomerase III [Geobacillus sp. JF8].	32.53	372	236	8	36	403	245	605	8e-45	176
rs:WP_008268666	DNA topoisomerase [Enterococcus sp. GMD1E].	31.54	409	238	15	61	454	165	546	8e-45	176
rs:WP_005812716	DNA topoisomerase III [Desulfitobacterium hafniense].	32.36	377	238	8	23	393	249	614	8e-45	177
rs:WP_010716652	DNA topoisomerase III, partial [Enterococcus faecalis].	32.61	417	243	12	52	452	7	401	8e-45	173
rs:WP_008667766	MULTISPECIES: DNA topoisomerase III [Bacteroides].	31.25	368	231	10	41	396	264	621	8e-45	176
rs:WP_031645736	DNA topoisomerase [Listeria monocytogenes].	32.13	414	249	10	52	452	264	658	8e-45	176
rs:WP_036823047	DNA topoisomerase III, partial [Polaribacter sp. Hel1_85].	29.28	403	254	9	38	416	231	626	8e-45	176
rs:WP_018361859	DNA topoisomerase III [Prevotella nanceiensis].	34.20	345	212	10	74	411	267	603	8e-45	176
rs:WP_032557320	DNA topoisomerase III [Bacteroides fragilis].	32.67	352	223	9	49	396	268	609	8e-45	176
rs:WP_010860920	DNA topoisomerase III [Lysinibacillus sphaericus].	29.36	436	274	11	36	450	244	666	8e-45	176
rs:WP_035690956	DNA topoisomerase III [Azospirillum halopraeferens].	35.38	342	191	10	67	385	258	592	8e-45	176
rs:WP_026981915	DNA topoisomerase III [Flavobacterium sp. URHB0058].	29.72	434	267	14	38	454	231	643	8e-45	176
rs:WP_011460046	DNA topoisomerase III [Desulfitobacterium hafniense].	32.36	377	238	8	23	393	249	614	8e-45	177
rs:WP_035658874	DNA topoisomerase III [Flavobacterium sp. EM1321].	29.40	432	271	12	38	454	231	643	8e-45	176
rs:WP_008880142	MULTISPECIES: DNA topoisomerase III [Geobacillus].	31.61	386	247	7	24	403	231	605	8e-45	176
rs:WP_021824609	DNA topoisomerase III [Prevotella salivae].	29.01	424	260	11	18	406	212	629	8e-45	176
rs:WP_020278829	DNA topoisomerase III [Geobacillus kaustophilus].	31.99	372	238	7	36	403	245	605	8e-45	176
rs:WP_047033420	DNA topoisomerase III [Elizabethkingia meningoseptica].	31.75	441	277	12	22	459	216	635	8e-45	176
rs:WP_018306873	DNA topoisomerase III [Desulfitobacterium hafniense].	32.63	377	237	8	23	393	249	614	8e-45	176
rs:WP_044225363	DNA topoisomerase III [Coprobacter sp. 177].	31.61	367	240	8	37	399	230	589	9e-45	176
rs:WP_009323494	DNA topoisomerase III [Subdoligranulum sp. 4_3_54A2FAA].	31.70	407	247	11	47	445	235	618	9e-45	176
tr:N9YPK9_9FIRM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ENZ09687.1};	32.41	435	251	14	23	445	100	503	9e-45	175
rs:WP_012840372	MULTISPECIES: DNA topoisomerase III [Comamonas].	34.14	372	226	8	40	399	263	627	9e-45	178
rs:WP_029232734	DNA topoisomerase [Butyrivibrio sp. VCB2006].	29.34	484	274	14	3	446	244	699	9e-45	179
rs:WP_032131993	DNA topoisomerase III [Weeksella sp. FF8].	33.53	346	219	7	40	384	233	568	9e-45	176
rs:WP_048009430	DNA topoisomerase III [Bacillus firmus].	30.11	435	268	12	36	453	244	659	9e-45	176
rs:WP_000838474	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	9e-45	176
rs:WP_000209238	DNA topoisomerase III [Bacillus cereus].	30.07	409	261	13	56	454	265	658	1e-44	176
rs:WP_000209235	DNA topoisomerase III [Bacillus cereus].	29.98	407	261	12	57	454	267	658	1e-44	176
rs:WP_025726041	DNA topoisomerase III [Bacteroides sp. 14(A)].	30.00	370	247	8	29	396	258	617	1e-44	176
rs:WP_024635937	DNA topoisomerase [Enterococcus faecium].	31.30	409	239	14	61	454	43	424	1e-44	173
rs:WP_015389938	DNA topoisomerase III [Kinetoplastibacterium blastocrithidii].	30.17	411	244	11	52	432	262	659	1e-44	177
rs:WP_000838477	DNA topoisomerase III [Staphylococcus aureus].	28.54	424	271	9	35	450	227	626	1e-44	176
rs:WP_004233245	DNA topoisomerase III [Lysinibacillus fusiformis].	29.00	431	268	14	36	450	248	656	1e-44	176
rs:WP_000838493	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	1e-44	176
rs:WP_038270228	hypothetical protein, partial [[Clostridium] clostridioforme].	32.41	435	251	14	23	445	107	510	1e-44	175
rs:WP_034767491	DNA topoisomerase III [Bacillus thermoamylovorans].	29.14	405	255	7	36	439	230	603	1e-44	176
rs:WP_047625860	DNA topoisomerase III [Enterobacter sp. ZOR0014].	31.57	415	263	8	31	432	240	646	1e-44	176
rs:WP_041519455	DNA topoisomerase III [Flavobacterium hibernum].	30.00	420	267	11	38	446	231	634	1e-44	176
rs:WP_015237730	DNA topoisomerase III [Kinetoplastibacterium blastocrithidii].	30.17	411	244	11	52	432	262	659	1e-44	177
rs:WP_002330416	hypothetical protein [Enterococcus faecium].	31.30	409	239	14	61	454	43	424	1e-44	173
rs:WP_035664890	DNA topoisomerase III [Bacillus akibai].	30.88	434	265	13	38	452	246	663	1e-44	176
rs:WP_007218955	DNA topoisomerase III [Bacteroides cellulosilyticus].	30.00	370	247	8	29	396	258	617	1e-44	176
rs:WP_010776959	DNA topoisomerase III, partial [Enterococcus faecium].	32.29	415	247	11	52	452	80	474	1e-44	173
tr:A0A017NAF6_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EYE44609.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EYE44609.1};	32.67	352	223	9	49	396	258	599	1e-44	176
rs:WP_046226190	DNA topoisomerase III [Paenibacillus dauci].	29.66	408	254	6	38	435	234	618	1e-44	176
rs:WP_046463202	DNA topoisomerase III [Staphylococcus aureus].	28.54	424	271	9	35	450	227	626	1e-44	176
rs:WP_037450141	DNA topoisomerase III [Skermanella stibiiresistens].	32.80	375	216	11	67	415	258	622	1e-44	176
rs:WP_031574346	DNA topoisomerase III [Proteiniclasticum ruminis].	31.10	418	257	8	39	450	231	623	1e-44	176
tr:T1AUZ1_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD60138.1}; Flags: Fragment;	34.60	289	178	6	47	334	52	330	1e-44	170
rs:WP_031860277	DNA topoisomerase III, partial [Staphylococcus aureus].	30.25	357	225	5	48	396	1	341	1e-44	170
rs:WP_000209240	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	29.31	406	265	11	57	454	267	658	1e-44	176
rs:WP_002314343	DNA topoisomerase [Enterococcus faecium].	31.30	409	239	14	61	454	43	424	1e-44	173
rs:WP_005678837	DNA topoisomerase III [Bacteroides caccae].	32.79	369	233	10	31	396	253	609	1e-44	176
rs:WP_019423903	DNA topoisomerase III [Paenibacillus sp. OSY-SE].	30.73	410	235	11	40	417	234	626	1e-44	176
rs:WP_026581149	DNA topoisomerase III [Bacillus sp. J33].	30.09	432	266	12	36	450	244	656	1e-44	176
rs:WP_040414532	DNA topoisomerase III [Cyclobacterium qasimii].	29.29	420	268	10	38	446	231	632	1e-44	176
tr:R3FTE9_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.21	416	246	11	52	452	108	502	1e-44	174
rs:WP_027865830	DNA topoisomerase III [Massilia alkalitolerans].	33.53	343	201	9	55	385	270	597	1e-44	177
rs:WP_033025446	DNA topoisomerase III [Geobacillus sp. CAMR5420].	31.99	372	238	7	36	403	245	605	1e-44	176
rs:WP_022101784	DNA topoisomerase III [Prevotella sp. CAG:5226].	32.05	365	231	9	49	402	272	630	1e-44	176
rs:WP_002368714	MULTISPECIES: DNA topoisomerase III [Enterococcus].	32.00	400	251	8	56	449	245	629	1e-44	176
rs:WP_031887564	DNA topoisomerase III, partial [Staphylococcus aureus].	30.00	370	235	5	35	396	227	580	1e-44	175
rs:WP_008823097	DNA topoisomerase III [Prevotella histicola].	31.25	400	242	10	24	396	221	614	1e-44	175
rs:WP_041929814	DNA topoisomerase III [Methylibium petroleiphilum].	33.33	378	222	9	40	400	263	627	1e-44	177
rs:WP_031872959	DNA topoisomerase III, partial [Staphylococcus aureus].	30.00	370	235	5	35	396	227	580	1e-44	175
rs:WP_005682722	DNA topoisomerase III [Bacteroides caccae].	32.79	369	233	10	31	396	253	609	1e-44	176
rs:WP_033626047	DNA topoisomerase [Enterococcus faecalis].	32.13	414	249	10	52	452	264	658	1e-44	176
rs:WP_029659095	DNA topoisomerase, partial [Enterococcus faecalis].	32.21	416	246	11	52	452	115	509	1e-44	174
rs:WP_026677034	DNA topoisomerase III [Fictibacillus gelatini].	27.98	436	282	10	36	453	244	665	1e-44	176
rs:WP_021539434	hypothetical protein [Escherichia coli].	30.07	409	269	9	38	432	248	653	1e-44	176
rs:WP_025571064	DNA topoisomerase III, partial [Flavobacterium sp. JGI 0001001-D01].	31.51	365	235	8	38	401	181	531	1e-44	176
rs:WP_022343863	DNA topoisomerase [Clostridium sp. CAG:356].	29.34	409	244	11	22	398	246	641	1e-44	175
rs:WP_033426509	hypothetical protein, partial [Salinicoccus albus].	30.23	430	270	12	31	445	105	519	1e-44	175
rs:WP_042276999	hypothetical protein, partial [Burkholderia fungorum].	34.69	369	224	7	40	398	240	601	1e-44	175
rs:WP_026597778	DNA topoisomerase III [Methylocystis sp. LW5].	33.08	390	223	13	38	400	230	608	1e-44	176
rs:WP_046175909	hypothetical protein [Domibacillus indicus].	29.34	426	275	9	36	453	247	654	1e-44	176
rs:WP_033623889	DNA topoisomerase, partial [Enterococcus faecalis].	32.61	417	243	12	52	452	68	462	1e-44	174
rs:WP_004081462	DNA topoisomerase III [Clostridium sp. ASF502].	32.45	416	250	13	40	445	231	625	1e-44	176
rs:WP_028593686	DNA topoisomerase III [Paenibacillus assamensis].	30.09	452	272	12	29	452	229	664	1e-44	176
rs:WP_028402778	DNA topoisomerase III [Bacillus panaciterrae].	33.06	360	217	9	36	385	244	589	1e-44	176
tr:A2SCD8_METPP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.33	378	222	9	40	400	279	643	1e-44	177
tr:G9QFT9_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.07	412	250	12	57	454	107	498	1e-44	174
rs:WP_029334830	DNA topoisomerase III [Exiguobacterium aurantiacum].	30.90	424	253	12	47	452	255	656	1e-44	176
rs:WP_025018050	DNA topoisomerase III [Bacteroides sartorii].	30.98	368	232	10	41	396	264	621	1e-44	176
rs:WP_016628541	DNA topoisomerase [Enterococcus faecium].	33.43	341	201	10	67	400	2	323	1e-44	170
rs:WP_003513145	DNA topoisomerase III [Ruminiclostridium thermocellum].	30.18	391	254	9	28	406	256	639	1e-44	175
rs:WP_000838478	DNA topoisomerase III [Staphylococcus aureus].	28.54	424	271	9	35	450	227	626	1e-44	176
rs:WP_012419017	DNA topoisomerase III [Bordetella avium].	34.71	363	206	9	38	385	252	598	2e-44	177
rs:WP_011722358	MULTISPECIES: DNA topoisomerase III [Clostridium].	30.67	450	263	16	35	446	260	698	2e-44	176
rs:WP_000838492	DNA topoisomerase III [Staphylococcus aureus].	28.77	424	270	9	35	450	227	626	2e-44	176
rs:WP_007156047	DNA topoisomerase III [Oribacterium sinus].	29.68	374	226	9	59	399	298	667	2e-44	175
rs:WP_041269880	DNA topoisomerase III, partial [Geobacillus sp. WCH70].	31.78	387	232	11	82	453	2	371	2e-44	172
tr:R4EHX8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.29	415	247	11	52	452	108	502	2e-44	173
rs:WP_022042877	DNA topoisomerase III [Bacteroides caccae CAG:21].	32.79	369	233	10	31	396	253	609	2e-44	176
rs:WP_014460501	DNA topoisomerase III [Bacillus megaterium].	31.29	441	258	14	36	453	244	662	2e-44	175
rs:WP_000838504	DNA topoisomerase III [Staphylococcus aureus].	28.30	424	272	9	35	450	227	626	2e-44	175
rs:WP_026777671	DNA topoisomerase III [Polaribacter sp. Hel_I_88].	29.79	386	257	8	18	402	212	584	2e-44	176
rs:WP_014680744	DNA topoisomerase III [Solitalea canadensis].	30.18	434	271	11	40	454	233	653	2e-44	175
rs:WP_009123155	DNA topoisomerase III [Bacteroides clarus].	31.81	371	239	9	30	396	257	617	2e-44	175
rs:WP_034893651	DNA topoisomerase III, partial [Candidatus Accumulibacter sp. SK-11].	32.28	381	226	9	40	401	255	622	2e-44	175
rs:WP_032088529	DNA topoisomerase III [Bacillus aquimaris].	27.13	435	284	9	36	453	244	662	2e-44	175
rs:WP_047757898	DNA topoisomerase III [Geobacillus sp. ZGt-1].	31.99	372	238	7	36	403	245	605	2e-44	175
rs:WP_033603659	DNA topoisomerase, partial [Enterococcus faecalis].	32.29	415	247	11	52	452	127	521	2e-44	174
rs:WP_047553798	DNA topoisomerase III [Staphylococcus aureus].	29.12	419	275	8	35	450	227	626	2e-44	175
rs:WP_010731590	DNA topoisomerase III, partial [Enterococcus faecalis].	31.73	416	248	11	52	452	44	438	2e-44	173
tr:E6LIS5_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.18	417	249	11	52	452	108	502	2e-44	174
rs:WP_010218667	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	39.92	253	148	3	31	281	236	486	2e-44	173
rs:WP_006162279	DNA topoisomerase III [Cupriavidus basilensis].	31.23	397	249	8	38	426	253	633	2e-44	177
rs:WP_028413674	DNA topoisomerase III [Bacillus sp. 278922_107].	31.29	441	258	14	36	453	244	662	2e-44	175
rs:WP_040176477	DNA topoisomerase III, partial [Klebsiella pneumoniae].	35.28	309	190	3	27	328	239	544	2e-44	174
rs:WP_027320953	DNA topoisomerase III [Bacillus sp. URHB0009].	29.00	400	253	6	36	434	230	599	2e-44	175
rs:WP_042371118	DNA topoisomerase III [Bacteroidaceae bacterium MS4].	34.05	326	201	8	74	396	267	581	2e-44	175
rs:WP_002578877	DNA topoisomerase III [[Clostridium] bolteae].	31.74	419	250	12	40	445	228	623	2e-44	175
rs:WP_000209236	DNA topoisomerase III [Bacillus cereus].	30.07	409	258	13	57	454	267	658	2e-44	175
rs:WP_044271662	DNA topoisomerase III [Candidatus Bacteroides timonensis].	29.73	370	248	8	29	396	258	617	2e-44	175
rs:WP_040202207	DNA topoisomerase III, partial [Klebsiella pneumoniae].	35.37	311	187	4	27	328	239	544	2e-44	174
tr:A0A066ZGK8_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.21	416	246	11	52	452	122	516	2e-44	174
rs:WP_013597426	DNA topoisomerase III [Weeksella virosa].	31.02	432	261	12	40	454	233	644	2e-44	175
tr:E6PWK5_9ZZZZ	SubName: Full=Putative DNA topoisomerase III, bacterial-type {ECO:0000313|EMBL:CBH99312.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBH99312.1};	33.71	356	212	8	41	385	260	602	2e-44	176
rs:WP_035639024	DNA topoisomerase III [Flavobacterium sp. EM1308].	29.86	432	269	12	38	454	231	643	2e-44	175
rs:WP_044742825	DNA topoisomerase III [Anoxybacillus sp. ATCC BAA-2555].	31.99	372	238	7	36	403	245	605	2e-44	175
rs:WP_009092056	DNA topoisomerase III [Elizabethkingia anophelis].	31.93	451	274	13	22	454	216	651	2e-44	175
rs:WP_010805658	DNA topoisomerase III [Pandoraea sp. SD6-2].	34.02	341	209	8	55	385	270	604	2e-44	177
rs:WP_034847279	DNA topoisomerase III [Elizabethkingia meningoseptica].	31.93	451	274	13	22	454	216	651	2e-44	175
rs:WP_006843458	DNA topoisomerase III [Dysgonomonas mossii].	31.55	374	244	9	37	406	230	595	2e-44	175
rs:WP_032448662	DNA topoisomerase III, partial [Klebsiella pneumoniae].	35.37	311	187	4	27	328	239	544	2e-44	174
rs:WP_046232591	DNA topoisomerase III [Paenibacillus algorifonticola].	33.41	419	236	14	31	413	220	631	2e-44	175
rs:WP_034230048	DNA topoisomerase, partial [Lachnobacterium bovis].	30.79	406	241	13	70	446	300	694	2e-44	175
rs:WP_021346323	DNA topoisomerase III [Elizabethkingia meningoseptica].	31.93	451	274	13	22	454	216	651	2e-44	175
rs:WP_016106882	DNA topoisomerase III [Bacillus cereus].	29.73	407	262	12	57	454	267	658	2e-44	175
rs:WP_007659952	DNA topoisomerase III [Bacteroides intestinalis].	29.73	370	248	8	29	396	258	617	2e-44	175
rs:WP_021967732	DNA topoisomerase III [Bacteroides intestinalis].	29.73	370	248	8	29	396	258	617	2e-44	175
rs:WP_025480915	DNA topoisomerase, partial [Enterococcus faecalis].	32.29	415	247	11	52	452	112	506	2e-44	173
rs:WP_033615871	DNA topoisomerase, partial [Enterococcus faecium].	32.29	415	247	11	52	452	127	521	2e-44	173
rs:WP_033421242	DNA topoisomerase, partial [Lachnobacterium bovis].	32.37	346	212	9	70	398	300	640	2e-44	175
rs:WP_032972388	DNA topoisomerase III [Bordetella hinzii].	34.99	363	205	9	38	385	252	598	2e-44	176
rs:WP_038167760	DNA topoisomerase III [Verrucomicrobium sp. BvORR106].	31.91	376	228	7	40	396	260	626	2e-44	176
rs:WP_023389097	DNA topoisomerase III [Youngiibacter fragilis].	30.81	396	252	7	39	428	231	610	2e-44	175
rs:WP_010709815	DNA topoisomerase III [Enterococcus faecalis].	30.15	408	256	10	57	449	269	662	2e-44	175
rs:WP_022490063	DNA topoisomerase [Clostridium sp. CAG:567].	30.43	368	234	10	50	398	104	468	2e-44	172
rs:WP_013488617	DNA topoisomerase III [Bacillus cellulosilyticus].	28.50	428	277	9	36	446	244	659	2e-44	175
rs:WP_015594677	DNA topoisomerase III [Bacillus sp. 1NLA3E].	29.10	433	275	10	36	453	244	659	2e-44	175
rs:WP_036915603	DNA topoisomerase III, partial [Prevotella sp. P6B4].	31.23	365	230	8	37	385	230	589	2e-44	174
rs:WP_044201455	DNA topoisomerase III [Flammeovirga sp. OC4].	31.04	364	241	7	37	396	230	587	2e-44	176
rs:WP_000838502	DNA topoisomerase 3 [Staphylococcus aureus].	28.54	424	271	9	35	450	227	626	2e-44	175
rs:WP_025729379	DNA topoisomerase III [Bacillus ginsengihumi].	29.29	437	277	11	36	456	246	666	2e-44	175
rs:WP_000838481	DNA topoisomerase III [Staphylococcus aureus].	28.54	424	271	9	35	450	227	626	2e-44	175
tr:C7VPQ1_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.61	417	243	12	52	452	79	473	2e-44	173
rs:WP_013063148	DNA topoisomerase III [Prevotella ruminicola].	31.09	386	237	11	24	385	217	597	2e-44	175
rs:WP_025729328	DNA topoisomerase III [Bacillus ginsengihumi].	29.52	420	244	10	36	445	230	607	2e-44	175
rs:WP_007134283	DNA topoisomerase III [Prevotella salivae].	28.77	424	261	11	18	406	212	629	2e-44	175
rs:WP_017466745	DNA topoisomerase III [Staphylococcus aureus].	28.54	424	271	9	35	450	227	626	3e-44	175
rs:WP_016289059	DNA topoisomerase III [Lachnospiraceae bacterium 3-1].	34.58	347	203	6	69	396	261	602	3e-44	175
rs:WP_000165793	hypothetical protein [Bacillus cereus].	28.54	410	265	7	50	446	140	534	3e-44	175
rs:WP_027136773	DNA topoisomerase III [Gaetbulibacter saemankumensis].	31.81	349	223	8	38	385	231	565	3e-44	175
rs:WP_018211376	DNA topoisomerase III [Desulfitobacterium hafniense].	33.06	363	226	8	37	393	263	614	3e-44	175
rs:WP_021253879	DNA topoisomerase III [Paenibacillus alvei].	30.53	380	229	8	40	391	234	606	3e-44	175
rs:WP_020491229	hypothetical protein [Dehalobacter sp. FTH1].	32.06	418	236	13	40	439	228	615	3e-44	174
rs:WP_029595302	DNA topoisomerase III [Exiguobacterium sp. GIC31].	31.84	424	249	12	47	452	255	656	3e-44	175
rs:WP_043810271	DNA topoisomerase [Rubrivivax gelatinosus].	31.19	404	249	8	40	428	251	640	3e-44	176
tr:J9H4U6_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJX11118.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EJX11118.1};	31.23	365	235	9	41	396	312	669	3e-44	175
rs:WP_047435386	DNA topoisomerase III [Staphylococcus aureus].	29.12	419	275	8	35	450	227	626	3e-44	175
rs:WP_000114569	DNA topoisomerase III [Bacillus cereus].	30.58	412	252	12	57	454	267	658	3e-44	174
rs:WP_040367708	DNA topoisomerase, partial [Enterococcus italicus].	31.18	417	249	11	52	452	148	542	3e-44	174
rs:WP_035333217	hypothetical protein [Bacillus firmus].	29.31	423	257	12	40	446	238	634	3e-44	174
rs:WP_022776439	DNA topoisomerase [Butyrivibrio sp. AE2015].	30.32	442	257	12	47	446	270	702	3e-44	177
rs:WP_015389216	DNA topoisomerase III [Candidatus Kinetoplastibacterium galatii].	30.33	399	238	9	61	432	274	659	3e-44	175
rs:WP_046242841	DNA topoisomerase III [Hymenobacter sp. MIMtkLc17].	30.30	396	250	10	35	413	252	638	3e-44	176
sp:TOP3_STAAR	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	28.54	424	271	9	35	450	227	626	3e-44	174
rs:WP_029486090	DNA topoisomerase [Enterococcus gallinarum].	32.13	414	249	10	52	452	264	658	3e-44	174
rs:WP_032962115	DNA topoisomerase III [Bordetella hinzii].	34.99	363	205	9	38	385	252	598	3e-44	176
rs:WP_000838509	DNA topoisomerase III [Staphylococcus aureus].	28.54	424	271	9	35	450	227	626	3e-44	174
rs:WP_045173686	DNA topoisomerase III [Staphylococcus aureus].	28.54	424	271	9	35	450	227	626	3e-44	174
rs:WP_002346508	DNA topoisomerase III [Streptococcus suis].	32.61	417	243	12	52	452	108	502	3e-44	173
rs:WP_032978941	DNA topoisomerase III [Bordetella hinzii].	34.99	363	205	9	38	385	252	598	3e-44	176
rs:WP_002338430	DNA topoisomerase III, partial [Enterococcus faecium].	32.05	415	248	11	52	452	199	593	3e-44	174
tr:B7IYV7_BACC2	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.54	410	265	7	50	446	133	527	3e-44	174
rs:WP_001573525	DNA topoisomerase 3 [Staphylococcus aureus].	28.94	425	268	10	35	450	227	626	3e-44	174
rs:WP_029577833	DNA topoisomerase III [Bordetella hinzii].	34.99	363	205	9	38	385	252	598	3e-44	176
rs:WP_032957599	DNA topoisomerase III [Bordetella hinzii].	34.99	363	205	9	38	385	252	598	3e-44	176
rs:WP_022473457	DNA topoisomerase [Sutterella sp. CAG:521].	32.88	371	209	10	71	425	286	632	3e-44	175
rs:WP_047751133	DNA topoisomerase III [Bacillus aryabhattai].	31.07	441	259	14	36	453	244	662	3e-44	174
rs:WP_022076992	DNA topoisomerase III [Clostridium sp. CAG:571].	30.30	406	241	13	22	398	246	638	3e-44	174
rs:WP_011803324	DNA topoisomerase III [Polaromonas naphthalenivorans].	32.33	399	246	10	40	425	265	652	3e-44	177
rs:WP_039370276	DNA topoisomerase III [Pandoraea pnomenusa].	34.01	344	205	10	55	385	270	604	3e-44	176
rs:WP_043223945	DNA topoisomerase III [Bordetella hinzii].	34.99	363	205	9	38	385	252	598	3e-44	176
rs:WP_046217659	DNA topoisomerase III, partial [Bacillus endophyticus].	28.85	409	238	7	36	434	142	507	3e-44	174
rs:WP_036227450	DNA topoisomerase III [Lysinibacillus sphaericus].	30.66	411	252	10	61	450	269	667	3e-44	174
rs:WP_013523825	MULTISPECIES: DNA topoisomerase III [Geobacillus].	31.45	372	240	7	36	403	245	605	3e-44	174
rs:WP_041903320	DNA topoisomerase III [Bacillus thermoamylovorans].	28.89	405	256	7	36	439	230	603	3e-44	174
rs:WP_004377279	DNA topoisomerase III [Prevotella oris].	28.86	499	282	15	18	454	212	699	3e-44	174
rs:WP_012375808	DNA topoisomerase III [Opitutus terrae].	31.69	385	228	9	36	396	251	624	3e-44	176
rs:WP_007845849	DNA topoisomerase III [Bacteroides dorei].	31.25	368	231	10	41	396	264	621	3e-44	174
rs:WP_033148685	DNA topoisomerase III, partial [Prevotella sp. P6B1].	31.23	365	230	8	37	385	230	589	4e-44	174
rs:WP_009332651	DNA topoisomerase III [Bacillus sp. 2_A_57_CT2].	29.20	435	272	12	36	453	244	659	4e-44	174
rs:WP_032941992	DNA topoisomerase III [Bacteroides massiliensis].	30.98	368	232	10	41	396	264	621	4e-44	174
rs:WP_033602985	DNA topoisomerase, partial [Enterococcus faecalis].	31.88	414	250	10	52	452	148	542	4e-44	173
rs:WP_044731386	DNA topoisomerase III [Geobacillus kaustophilus].	31.72	372	239	7	36	403	245	605	4e-44	174
tr:D4J464_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.70	417	251	7	16	428	219	601	4e-44	174
rs:WP_019379736	DNA topoisomerase III [Bacillus oceanisediminis].	29.20	435	272	12	36	453	244	659	4e-44	174
rs:WP_029655964	DNA topoisomerase, partial [Enterococcus faecalis].	32.21	416	246	11	52	452	115	509	4e-44	173
rs:WP_043210668	DNA topoisomerase III [Bordetella sp. 8-296-03].	34.99	363	205	9	38	385	252	598	4e-44	176
rs:WP_000063789	DNA topoisomerase [Bacillus cereus].	31.75	378	224	11	93	455	307	665	4e-44	174
rs:WP_041966979	DNA topoisomerase III [Bacillus selenatarsenatis].	29.20	435	274	9	36	453	244	661	4e-44	174
rs:WP_008982719	DNA topoisomerase III [Ruminococcaceae bacterium D16].	31.45	407	248	11	47	445	235	618	4e-44	174
rs:WP_016128093	DNA topoisomerase III [Bacillus cereus].	28.99	407	265	11	57	454	267	658	4e-44	174
rs:WP_034866021	DNA topoisomerase III [Elizabethkingia miricola].	32.06	446	270	13	22	449	216	646	4e-44	174
rs:WP_029675935	MULTISPECIES: DNA topoisomerase, partial [Bacilli].	32.61	417	243	12	52	452	148	542	4e-44	174
rs:WP_020756607	DNA topoisomerase III [Geobacillus sp. WSUCF1].	31.99	372	238	7	36	403	245	605	4e-44	174
rs:WP_002320596	DNA topoisomerase [Enterococcus faecium].	31.88	414	250	10	52	452	241	635	4e-44	174
rs:WP_000209237	DNA topoisomerase III [Bacillus cereus].	29.48	407	263	11	57	454	267	658	4e-44	174
rs:WP_028545721	DNA topoisomerase III [Paenibacillus taiwanensis].	29.58	409	256	8	34	435	229	612	4e-44	174
rs:WP_047818436	DNA topoisomerase III [Geobacillus sp. 12AMOR1].	31.10	373	240	7	36	403	245	605	4e-44	174
rs:WP_033630599	DNA topoisomerase, partial [Enterococcus faecium].	32.61	417	243	12	52	452	148	542	4e-44	173
rs:WP_010539317	DNA topoisomerase III [Bacteroides faecis].	31.71	369	237	10	31	396	252	608	4e-44	174
rs:WP_023281073	MULTISPECIES: hypothetical protein [Enterobacteriaceae].	31.73	416	261	9	31	432	240	646	4e-44	174
rs:WP_000209239	DNA topoisomerase III [Bacillus cereus].	29.48	407	263	12	57	454	267	658	4e-44	174
rs:WP_008810305	DNA topoisomerase III [Parasutterella excrementihominis].	32.74	394	228	11	47	425	261	632	4e-44	175
rs:WP_011231305	DNA topoisomerase III [Geobacillus kaustophilus].	31.99	372	238	7	36	403	245	605	4e-44	174
rs:WP_005667883	DNA topoisomerase III [Massilia timonae].	32.28	381	231	10	55	425	270	633	5e-44	176
rs:WP_004371446	DNA topoisomerase III [Prevotella oris].	29.93	411	249	10	18	396	212	615	5e-44	174
rs:WP_033016990	DNA topoisomerase III [Geobacillus stearothermophilus].	31.99	372	238	7	36	403	245	605	5e-44	174
rs:WP_033121899	DNA topoisomerase III [Oscillibacter sp. ER4].	31.44	388	241	9	47	426	235	605	5e-44	174
rs:WP_039064406	DNA topoisomerase III, partial [Shigella boydii].	31.73	416	261	9	31	432	175	581	5e-44	174
tr:R9I6C5_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOS11739.1};	30.98	368	232	10	41	396	280	637	5e-44	174
tr:A0A069D2D9_9LACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.30	439	259	17	35	450	41	455	5e-44	172
rs:WP_032494175	topoisomerase I, partial [Enterococcus faecium].	32.29	415	247	11	52	452	149	543	5e-44	173
rs:WP_026626030	DNA topoisomerase III [Dysgonomonas capnocytophagoides].	35.00	320	189	8	74	385	267	575	5e-44	174
tr:C7UVJ8_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.61	417	243	12	52	452	160	554	5e-44	173
rs:WP_000114568	DNA topoisomerase III [Bacillus thuringiensis].	30.49	410	255	11	57	454	267	658	5e-44	174
rs:WP_010728928	DNA topoisomerase III [Enterococcus faecium].	33.62	348	205	10	65	405	169	497	5e-44	172
rs:WP_025950702	DNA topoisomerase III [Geobacillus thermocatenulatus].	30.14	428	277	10	36	453	245	660	5e-44	174
rs:WP_010899528	DNA topoisomerase III [Bacillus halodurans].	30.34	435	269	11	36	452	246	664	5e-44	174
gp:CP010941_2189	DNA topoisomerase III [Staphylococcus aureus]	28.54	424	271	9	35	450	227	626	5e-44	174
rs:WP_021311269	DNA topoisomerase III [Bacteroidetes bacterium oral taxon 272].	30.05	426	271	12	23	432	240	654	5e-44	174
gpu:CP011974_2962	174	28.85	409	238	7	36	434	230	595	5e-44
rs:WP_021261414	DNA topoisomerase III [Paenibacillus alvei].	30.53	380	229	8	40	391	234	606	5e-44	174
rs:WP_001241818	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	31.73	416	261	9	31	432	240	646	6e-44	174
rs:WP_028533041	DNA topoisomerase III [Paenibacillus sp. UNC217MF].	30.53	380	229	8	40	391	234	606	6e-44	174
rs:WP_011244861	DNA topoisomerase [Bacillus thuringiensis].	30.49	410	255	11	57	454	273	664	6e-44	174
rs:WP_024882202	DNA topoisomerase III [Methylosinus sp. LW3].	32.66	395	231	13	38	406	230	615	6e-44	174
rs:WP_008766576	DNA topoisomerase III [Bacteroides sp. 1_1_6].	31.71	369	237	10	31	396	252	608	6e-44	174
gp:FP929058_263	DNA topoisomerase III, bacteria and conjugative plasmid [Enterococcus sp. 7L76]	31.64	414	251	10	52	452	264	658	6e-44	174
rs:WP_000108741	MULTISPECIES: DNA topoisomerase [Bacilli].	31.40	414	252	10	52	452	264	658	6e-44	174
rs:WP_041512402	DNA topoisomerase III [Nitrosospira sp. NpAV].	32.41	398	241	13	40	426	255	635	6e-44	175
rs:WP_007084794	DNA topoisomerase III [Bacillus bataviensis].	29.66	435	258	13	36	446	244	654	6e-44	174
tr:R1K8N3_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.64	414	251	10	52	452	264	658	6e-44	174
rs:WP_046228621	DNA topoisomerase III [Paenibacillus algorifonticola].	31.08	415	242	9	31	428	229	616	6e-44	174
rs:WP_000165791	DNA topoisomerase III [Bacillus thuringiensis].	28.57	413	267	7	47	446	137	534	6e-44	174
rs:WP_042113879	DNA topoisomerase III [Pandoraea apista].	34.02	341	209	8	55	385	270	604	6e-44	175
rs:WP_040287707	DNA topoisomerase III [Sporosarcina koreensis].	31.00	429	258	14	46	454	251	661	6e-44	174
rs:WP_002326769	DNA topoisomerase III, partial [Enterococcus faecium].	32.29	415	247	11	52	452	264	658	6e-44	173
rs:WP_004334692	DNA topoisomerase III [Porphyromonas endodontalis].	32.97	367	219	9	47	396	240	596	6e-44	173
rs:WP_034194828	hypothetical protein, partial [Burkholderia sp. WP42].	36.36	319	179	10	156	455	1	314	6e-44	167
rs:WP_029485677	DNA topoisomerase, partial [Enterococcus faecium].	31.73	416	248	11	52	452	26	420	7e-44	171
rs:WP_019155274	DNA topoisomerase III [Bacillus massiliosenegalensis].	28.57	406	248	7	35	434	229	598	7e-44	174
rs:WP_036165815	DNA topoisomerase III [Lysinibacillus sphaericus].	27.89	441	279	12	25	455	246	657	7e-44	174
rs:WP_002341369	DNA topoisomerase III [Enterococcus faecium].	33.82	343	201	10	65	400	169	492	7e-44	171
rs:WP_010731205	DNA topoisomerase III [Enterococcus faecium].	32.29	415	247	11	52	452	264	658	7e-44	174
rs:WP_038291301	DNA topoisomerase [[Clostridium] straminisolvens].	30.55	383	247	9	29	399	257	632	7e-44	173
tr:A0A011RAP0_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.98	394	223	12	56	425	271	643	7e-44	175
tr:A0A098AZW1_DESHA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.33	363	225	8	37	393	263	614	7e-44	174
rs:WP_013438841	topoisomerase [Enterococcus faecalis].	32.29	415	247	11	52	452	264	658	7e-44	173
rs:WP_008246963	DNA topoisomerase III [Limnobacter sp. MED105].	31.34	402	244	9	40	426	258	642	7e-44	174
rs:WP_035674309	DNA topoisomerase III [Flavobacterium sp. 83].	31.17	369	236	9	38	401	231	586	7e-44	174
rs:WP_016284600	DNA topoisomerase III [Lachnospiraceae bacterium A4].	32.21	416	251	13	40	445	119	513	7e-44	172
rs:WP_041845841	DNA topoisomerase III [Bacillus thermoamylovorans].	28.89	405	256	7	36	439	230	603	7e-44	173
rs:WP_022937740	DNA topoisomerase III [Dielma fastidiosa].	28.44	429	270	10	32	450	236	637	7e-44	173
rs:WP_010742428	DNA topoisomerase III [Enterococcus malodoratus].	31.78	409	237	15	61	454	165	546	7e-44	173
rs:WP_000108743	MULTISPECIES: DNA topoisomerase [Bacilli].	32.29	415	247	11	52	452	264	658	8e-44	173
tr:A5ZNQ6_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.53	375	226	11	34	397	156	514	8e-44	173
rs:WP_044393261	DNA topoisomerase III [Bacillus subterraneus].	30.59	438	264	13	36	453	244	661	8e-44	173
rs:WP_002339809	DNA topoisomerase III [Enterococcus faecium].	31.64	414	251	10	52	452	264	658	8e-44	173
rs:WP_003610064	DNA topoisomerase III [Methylosinus trichosporium].	34.47	351	197	11	69	396	260	600	8e-44	173
rs:WP_029473397	DNA topoisomerase III [Clostridiales bacterium VE202-08].	28.44	429	270	10	32	450	236	637	8e-44	173
rs:WP_044337013	DNA topoisomerase III [Bacillus aquimaris].	27.06	436	283	10	36	453	244	662	8e-44	173
rs:WP_002356083	DNA topoisomerase [Enterococcus faecium].	33.82	343	201	10	65	400	169	492	8e-44	171
rs:WP_016627781	DNA topoisomerase [Enterococcus faecium].	31.05	409	240	14	61	454	43	424	8e-44	171
rs:WP_045706786	DNA topoisomerase III [Desulfobulbaceae bacterium BRH_c16a].	31.23	365	215	8	36	385	257	600	8e-44	174
rs:WP_047390291	DNA topoisomerase III [Carnobacterium sp. ZWU0011].	30.13	395	247	11	71	454	275	651	8e-44	173
rs:WP_002307507	DNA topoisomerase [Enterococcus faecium].	33.82	343	201	10	65	400	169	492	8e-44	171
rs:WP_024565255	DNA topoisomerase III [Elizabethkingia anophelis].	31.84	446	271	13	22	449	216	646	8e-44	173
tr:A0A0B5GGH3_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.88	414	250	10	52	452	264	658	8e-44	173
rs:WP_021013085	DNA topoisomerase 3 [Variovorax paradoxus].	32.61	368	223	11	47	399	276	633	8e-44	175
rs:WP_000115174	DNA topoisomerase III [Bacillus thuringiensis].	30.56	409	256	12	57	454	267	658	8e-44	173
rs:WP_028604968	DNA topoisomerase III [Ottowia thiooxydans].	30.79	419	230	10	34	400	252	662	8e-44	176
rs:WP_004192797	DNA topoisomerase III [Klebsiella pneumoniae].	31.80	412	258	9	35	432	244	646	9e-44	173
rs:WP_047937029	DNA topoisomerase [Enterococcus faecium].	34.11	343	200	11	65	400	169	492	9e-44	171
rs:WP_018919556	DNA topoisomerase III [Prevotella oris].	30.00	410	250	10	18	396	212	615	9e-44	173
rs:WP_035478371	hypothetical protein, partial [Burkholderia phenoliruptrix].	35.34	348	208	7	40	377	240	580	9e-44	172
rs:WP_031453405	DNA topoisomerase III [Flavobacterium chungangense].	31.51	365	235	8	38	401	231	581	9e-44	174
rs:WP_013964628	DNA topoisomerase III [Nitrosomonas sp. Is79A3].	33.50	400	232	15	40	425	255	634	9e-44	174
rs:WP_008759804	DNA topoisomerase III [Bacteroides sp. 1_1_14].	31.71	369	237	10	31	396	252	608	9e-44	173
rs:WP_044737023	DNA topoisomerase III [Geobacillus kaustophilus].	31.45	372	240	7	36	403	245	605	9e-44	173
rs:WP_012247063	DNA topoisomerase III [Bordetella petrii].	34.71	363	206	9	38	385	252	598	9e-44	174
rs:WP_034225946	DNA topoisomerase, partial [Lachnobacterium bovis].	32.08	346	213	9	70	398	300	640	9e-44	173
rs:WP_007287723	DNA topoisomerase III [Intestinibacter bartlettii].	30.91	372	219	7	61	428	261	598	9e-44	173
rs:WP_032640105	DNA topoisomerase III [Enterobacter sp. EGD-HP1].	31.33	415	264	8	31	432	240	646	9e-44	173
rs:WP_016289972	DNA topoisomerase III [Lachnospiraceae bacterium 28-4].	33.25	418	246	15	40	445	231	627	9e-44	173
rs:WP_045147099	DNA topoisomerase III [Peptoclostridium difficile].	32.45	416	250	12	40	445	230	624	9e-44	173
rs:WP_004178242	DNA topoisomerase III [Nitrosospira lacus].	33.42	398	235	14	40	425	255	634	9e-44	174
tr:A0A060NIK4_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.34	364	212	11	40	385	271	625	1e-43	175
rs:WP_028898264	DNA topoisomerase III [Prevotella sp. HUN102].	30.33	422	248	13	18	401	217	630	1e-43	173
rs:WP_041090884	DNA topoisomerase III [Jeotgalibacillus soli Cunha et al. 2012].	31.30	393	240	13	74	454	283	657	1e-43	173
rs:WP_046467158	DNA topoisomerase III [Staphylococcus pasteuri].	29.22	421	272	9	35	450	228	627	1e-43	173
rs:WP_016222100	DNA topoisomerase III [Dorea sp. 5-2].	31.48	413	256	9	40	445	230	622	1e-43	173
rs:WP_047795214	DNA topoisomerase III [Exiguobacterium sp. JLM-2].	31.26	419	245	11	47	446	255	649	1e-43	173
rs:WP_021752614	DNA topoisomerase III [Gemella bergeri].	30.00	380	245	6	66	445	256	614	1e-43	173
tr:L2H5I4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.73	416	248	11	52	452	82	476	1e-43	172
rs:WP_017170432	hypothetical protein [Xanthomonas axonopodis].	32.28	412	232	13	40	427	265	653	1e-43	174
rs:WP_043064063	DNA topoisomerase III [Aneurinibacillus migulanus].	31.51	438	264	12	36	453	244	665	1e-43	173
rs:WP_026494579	DNA topoisomerase [Butyrivibrio sp. WCD3002].	30.57	435	255	12	47	446	270	692	1e-43	176
rs:WP_028509289	hypothetical protein [Ruminococcus sp. NK3A76].	29.90	408	260	8	47	449	234	620	1e-43	173
rs:WP_045181198	DNA topoisomerase III [Elizabethkingia sp. BM10].	31.75	441	277	12	22	459	216	635	1e-43	173
rs:WP_022471349	DNA topoisomerase III [Bacteroides thetaiotaomicron CAG:40].	31.71	369	237	10	31	396	252	608	1e-43	173
rs:WP_033655835	DNA topoisomerase, partial [Enterococcus faecium].	31.73	416	248	11	52	452	83	477	1e-43	171
rs:WP_025910233	DNA topoisomerase III [Bacillus flexus].	30.00	400	242	6	38	435	232	595	1e-43	173
rs:WP_007766830	DNA topoisomerase III [Bacteroides finegoldii].	32.29	353	227	9	47	396	267	610	1e-43	173
rs:WP_008816171	DNA topoisomerase III [Erysipelotrichaceae bacterium 6_1_45].	31.44	388	241	9	47	426	235	605	1e-43	173
rs:WP_029768989	hypothetical protein, partial [Ralstonia mannitolilytica].	33.96	371	207	11	36	385	222	575	1e-43	172
rs:WP_044925917	DNA topoisomerase III [[Ruminococcus] obeum].	32.53	375	226	11	34	397	221	579	1e-43	173
tr:H0DFI8_9STAP	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.40	412	272	8	43	450	235	627	1e-43	173
rs:WP_008101325	DNA topoisomerase [Verrucomicrobiae bacterium DG1235].	30.97	423	266	9	39	455	233	635	1e-43	173
rs:WP_000838503	DNA topoisomerase 3 [Staphylococcus aureus].	28.30	424	272	9	35	450	227	626	1e-43	173
rs:WP_045533713	DNA topoisomerase III, partial [Comamonadaceae bacterium A1].	34.34	364	212	11	40	385	269	623	1e-43	174
tr:E3PWY5_CLOSD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.07	449	271	16	41	457	218	655	1e-43	173
rs:WP_031423395	DNA topoisomerase III [Exiguobacterium sp. NG55].	31.26	419	245	11	47	446	255	649	1e-43	173
rs:WP_044467849	DNA topoisomerase III [Bacteroides uniformis].	31.00	371	243	9	29	396	258	618	1e-43	173
rs:WP_002328357	DNA topoisomerase III [Enterococcus faecium].	33.82	343	201	10	65	400	169	492	1e-43	171
rs:WP_040056402	DNA topoisomerase III [Bacillus sp. REN51N].	28.61	409	239	7	36	434	230	595	1e-43	173
rs:WP_043431407	ATP-dependent DNA helicase RecQ [Cystobacter fuscus].	32.81	381	228	7	43	398	264	641	1e-43	176
rs:WP_042441694	DNA topoisomerase III, partial [Rhodopseudomonas palustris].	32.34	337	204	8	91	408	1	332	1e-43	171
rs:WP_039217288	MULTISPECIES: DNA topoisomerase III [Clostridium].	29.39	473	284	16	22	454	246	708	1e-43	173
rs:WP_038146532	DNA topoisomerase III [Verrucomicrobia bacterium SCGC AAA027-I19].	33.42	386	219	12	40	403	263	632	1e-43	174
rs:WP_047929732	DNA topoisomerase [Enterococcus faecium].	33.82	343	201	10	65	400	169	492	1e-43	171
tr:S9PA36_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.81	381	228	7	43	398	257	634	1e-43	176
rs:WP_019375117	DNA topoisomerase III [Alicycliphilus sp. CRZ1].	32.82	387	227	9	40	400	263	642	1e-43	175
rs:WP_039234196	DNA topoisomerase III [Clostridium sp. K25].	29.39	473	284	16	22	454	246	708	1e-43	173
rs:WP_044188344	ATP-dependent DNA helicase RecQ [Hyalangium minutum].	33.07	384	232	7	43	403	294	675	1e-43	176
rs:WP_000165792	DNA topoisomerase III [Bacillus cereus].	28.33	413	268	7	47	446	137	534	1e-43	172
rs:WP_032967783	DNA topoisomerase III [Bordetella holmesii].	34.44	363	207	9	38	385	252	598	1e-43	174
rs:WP_026686798	DNA topoisomerase III [Azovibrio restrictus].	31.99	422	237	14	40	435	259	656	1e-43	174
rs:WP_000165790	DNA topoisomerase III [Bacillus thuringiensis].	27.94	408	276	6	47	446	137	534	1e-43	172
rs:WP_007751728	DNA topoisomerase III [Bacteroides finegoldii].	32.29	353	227	9	47	396	267	610	1e-43	172
rs:WP_033150038	DNA topoisomerase III [Prevotella sp. RM4].	30.56	373	242	9	24	385	217	583	1e-43	172
rs:WP_008664059	DNA topoisomerase III [Bacteroides sp. 4_1_36].	31.00	371	243	9	29	396	258	618	1e-43	173
rs:WP_047753083	DNA topoisomerase III [Geobacillus sp. T6].	31.72	372	239	7	36	403	245	605	1e-43	173
rs:WP_024741910	DNA topoisomerase III [Tenacibaculum maritimum].	31.38	392	254	9	18	402	212	595	1e-43	173
rs:WP_012726527	DNA topoisomerase III [Exiguobacterium sp. AT1b].	31.26	419	245	11	47	446	255	649	1e-43	172
rs:WP_035854511	DNA topoisomerase III [Dechloromonas agitata].	33.33	426	231	15	40	438	255	654	1e-43	174
rs:WP_015844258	DNA topoisomerase III [Paenibacillus sp. JDR-2].	33.33	390	224	11	31	391	220	602	1e-43	173
rs:WP_027321998	DNA topoisomerase III [Bacillus sp. URHB0009].	29.51	427	268	11	36	446	244	653	1e-43	173
rs:WP_016268580	DNA topoisomerase III [Bacteroides thetaiotaomicron].	31.71	369	237	10	31	396	252	608	1e-43	172
rs:WP_027724303	DNA topoisomerase III [Tuberibacillus calidus].	30.97	352	211	4	38	385	232	555	1e-43	172
rs:WP_022113658	DNA topoisomerase [Clostridium sp. CAG:245].	30.33	399	247	11	22	392	247	642	1e-43	172
rs:WP_029658328	DNA topoisomerase, partial [Enterococcus faecalis].	32.37	417	244	12	52	452	115	509	1e-43	172
rs:WP_038012980	DNA topoisomerase III, partial [Terasakiella pusilla].	32.51	446	249	17	40	451	232	659	1e-43	172
tr:A0A085WJV1_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.07	384	232	7	43	403	261	642	1e-43	176
rs:WP_046442595	DNA topoisomerase III [Catabacter hongkongensis].	31.17	369	243	6	35	399	222	583	1e-43	172
rs:WP_022508538	DNA topoisomerase III [Bacteroides vulgatus CAG:6].	30.98	368	232	10	41	396	264	621	1e-43	172
rs:WP_005845872	DNA topoisomerase III [Bacteroides vulgatus].	30.98	368	232	10	41	396	264	621	1e-43	172
rs:WP_005017120	DNA topoisomerase III [Bordetella holmesii].	34.44	363	207	9	38	385	252	598	1e-43	174
rs:WP_037022461	MULTISPECIES: hypothetical protein, partial [Ralstonia].	33.96	371	207	11	36	385	222	575	1e-43	172
rs:WP_022041252	DNA topoisomerase III [Bacteroides sp. CAG:702].	31.39	360	231	9	41	396	265	612	1e-43	172
rs:WP_046409534	DNA topoisomerase III [Bacteroides sp. N54.MGS-20].	30.93	375	242	8	37	407	230	591	2e-43	172
rs:WP_028462024	DNA topoisomerase III [Nitrosomonas cryotolerans].	33.25	409	240	15	40	435	255	643	2e-43	174
rs:WP_033467544	DNA topoisomerase III [Bordetella bronchiseptica].	34.16	363	208	9	38	385	252	598	2e-43	174
rs:WP_017759289	DNA topoisomerase III [Pseudacidovorax intermedius].	34.01	347	204	10	54	385	285	621	2e-43	175
rs:WP_026833507	DNA topoisomerase III [Exiguobacterium undae].	30.61	428	263	12	40	454	245	651	2e-43	172
rs:WP_047211734	DNA topoisomerase III [Staphylococcus aureus].	28.30	424	272	9	35	450	227	626	2e-43	172
rs:WP_032826676	DNA topoisomerase III [Bordetella holmesii].	34.44	363	207	9	38	385	252	598	2e-43	174
tr:G4B181_AGGAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	37.28	228	136	2	36	263	259	479	2e-43	171
rs:WP_031533880	MULTISPECIES: DNA topoisomerase III [Bacteroides].	30.79	367	237	9	37	396	230	586	2e-43	172
rs:WP_041487101	DNA topoisomerase III [[Clostridium] sticklandii].	30.07	449	271	16	41	457	266	703	2e-43	172
rs:WP_002342368	DNA topoisomerase III [Enterococcus faecium].	33.82	343	201	10	65	400	169	492	2e-43	171
rs:WP_022199129	DNA topoisomerase III [Bacteroides ovatus CAG:22].	31.44	369	238	10	31	396	252	608	2e-43	172
rs:WP_000838498	DNA topoisomerase 3 [Staphylococcus aureus].	28.30	424	272	9	35	450	227	626	2e-43	172
rs:WP_009961403	DNA topoisomerase III [Verrucomicrobium spinosum].	31.91	376	228	7	40	396	260	626	2e-43	174
rs:WP_017415987	hypothetical protein [Clostridium tunisiense].	31.74	356	219	9	61	401	287	633	2e-43	172
rs:WP_015396725	DNA topoisomerase III [Candidatus Kinetoplastibacterium oncopeltii].	31.23	397	234	11	63	432	275	659	2e-43	173
rs:WP_010731398	DNA topoisomerase III [Enterococcus faecium].	31.40	414	252	10	52	452	264	658	2e-43	172
rs:WP_028106718	DNA topoisomerase III [Exiguobacterium undae].	31.09	431	257	13	40	454	245	651	2e-43	172
rs:WP_022275766	DNA topoisomerase III [Bacteroides finegoldii CAG:203].	32.29	353	227	9	47	396	267	610	2e-43	172
rs:WP_002461797	DNA topoisomerase III [Staphylococcus simiae].	26.79	433	267	9	35	450	227	626	2e-43	172
tr:W7CFI9_BROTH	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.83	399	248	8	1	391	196	578	2e-43	172
rs:WP_004321870	MULTISPECIES: DNA topoisomerase III [Bacteroides].	31.44	369	238	10	31	396	252	608	2e-43	172
rs:WP_007579075	DNA topoisomerase III [Patulibacter medicamentivorans].	29.82	446	264	14	37	449	254	683	2e-43	173
rs:WP_034674086	DNA topoisomerase III, partial [Bacillus niacini].	29.01	424	275	9	36	446	244	654	2e-43	172
rs:WP_044996546	DNA topoisomerase III [Blautia wexlerae].	31.00	400	244	10	40	425	231	612	2e-43	172
rs:WP_031929785	DNA topoisomerase, partial [Staphylococcus aureus].	32.98	376	214	12	93	452	24	377	2e-43	169
tr:A7LZL4_BACO1	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EDO11386.1};	31.44	369	238	10	31	396	252	608	2e-43	172
rs:WP_036822275	DNA topoisomerase III [Pontibacillus yanchengensis].	28.26	407	265	11	58	454	269	658	2e-43	172
rs:WP_029645005	MULTISPECIES: DNA topoisomerase, partial [Lactobacillales].	32.79	369	214	11	98	452	1	349	2e-43	167
rs:WP_021315120	DNA topoisomerase III [Dehalobacter sp. UNSWDHB].	32.80	436	251	16	27	449	214	620	2e-43	172
rs:WP_039282953	DNA topoisomerase III [Clostridium botulinum].	29.76	457	258	15	35	446	260	698	2e-43	172
rs:WP_035051234	DNA topoisomerase III [Carnobacterium pleistocenium].	29.76	410	255	13	58	454	262	651	2e-43	172
tr:A0A060NXQ2_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.34	364	212	11	40	385	272	626	2e-43	174
rs:WP_029333124	DNA topoisomerase III [Exiguobacterium oxidotolerans].	30.30	429	264	11	40	454	245	652	2e-43	172
rs:WP_007201190	DNA topoisomerase III [Fictibacillus macauensis].	30.42	401	256	9	56	446	267	654	2e-43	172
rs:WP_019653808	DNA topoisomerase III [Variovorax paradoxus].	32.53	375	230	10	40	399	271	637	2e-43	174
rs:WP_001776115	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	31.49	416	262	9	31	432	240	646	2e-43	172
rs:WP_004326163	DNA topoisomerase III [Bacteroides ovatus].	31.44	369	238	10	31	396	252	608	2e-43	172
rs:WP_019967377	DNA topoisomerase III [Prevotella maculosa].	29.72	424	257	11	18	406	212	629	2e-43	172
rs:WP_000108742	MULTISPECIES: hypothetical protein [Lactobacillales].	31.57	415	250	11	52	452	264	658	2e-43	172
rs:WP_027451300	DNA topoisomerase III [Porphyromonas uenonis].	34.02	338	207	10	47	375	248	578	2e-43	171
rs:WP_003375986	DNA topoisomerase III [Clostridium botulinum].	29.39	473	284	16	22	454	246	708	2e-43	172
rs:WP_024980194	DNA topoisomerase III [Flavobacterium succinicans].	29.06	437	271	13	38	454	231	648	2e-43	172
rs:WP_022544106	DNA topoisomerase III [Bacillus infantis].	29.00	431	274	10	36	446	244	662	2e-43	172
rs:WP_004306716	MULTISPECIES: DNA topoisomerase III [Bacteroides].	31.44	369	238	10	31	396	252	608	2e-43	172
rs:WP_004611958	DNA topoisomerase III [Tyzzerella nexilis].	30.99	413	242	13	47	445	235	618	2e-43	172
rs:WP_047787439	DNA topoisomerase III [Variovorax paradoxus].	32.34	368	224	11	47	399	276	633	2e-43	174
rs:WP_036287960	DNA topoisomerase III [Methylosinus sp. PW1].	32.56	390	225	13	38	400	230	608	2e-43	172
rs:WP_023208305	DNA topoisomerase III [Salmonella enterica].	31.87	364	235	5	31	385	240	599	2e-43	172
rs:WP_029466987	DNA topoisomerase III [Hungatella hathewayi].	31.52	441	258	15	27	450	214	627	2e-43	172
rs:WP_002343776	MULTISPECIES: DNA topoisomerase III [Lactobacillales].	32.05	415	248	11	52	452	264	658	2e-43	172
rs:WP_029486035	DNA topoisomerase [Enterococcus gallinarum].	31.57	415	250	11	52	452	264	658	2e-43	172
rs:WP_036027634	DNA topoisomerase III [Brochothrix thermosphacta].	31.83	399	248	8	1	391	196	578	2e-43	172
rs:WP_004312405	DNA topoisomerase III [Bacteroides ovatus].	31.44	369	238	10	31	396	252	608	2e-43	172
rs:WP_019392302	DNA topoisomerase III [Bacillus endophyticus].	28.36	409	240	7	36	434	230	595	2e-43	172
rs:WP_047556277	DNA topoisomerase III [Staphylococcus aureus].	28.88	419	276	8	35	450	227	626	2e-43	172
rs:WP_031892894	DNA topoisomerase III, partial [Staphylococcus aureus].	31.10	328	202	5	77	396	8	319	3e-43	166
rs:WP_004331116	DNA topoisomerase III [Porphyromonas asaccharolytica].	33.63	336	211	9	47	375	248	578	3e-43	171
rs:WP_045538028	DNA topoisomerase III, partial [Comamonadaceae bacterium B1].	34.34	364	212	11	40	385	271	625	3e-43	174
rs:WP_032119137	DNA topoisomerase III [Clostridium sp. CL-2].	34.83	356	206	11	59	399	287	631	3e-43	171
rs:WP_014269454	DNA topoisomerase III [Sphaerochaeta pleomorpha].	32.85	347	219	6	47	385	242	582	3e-43	172
rs:WP_024727223	DNA topoisomerase III [Clostridiales bacterium VE202-09].	30.00	380	226	6	53	425	250	596	3e-43	172
rs:WP_019468637	MULTISPECIES: DNA topoisomerase III [Staphylococcus].	28.85	357	241	3	43	396	235	581	3e-43	172
rs:WP_042513650	hypothetical protein [Bacillus anthracis].	29.97	387	247	12	77	454	2	373	3e-43	167
rs:WP_009249981	DNA topoisomerase III [Lachnospiraceae bacterium 3_1_57FAA_CT1].	32.45	379	228	10	34	404	221	579	3e-43	172
rs:WP_047592215	DNA topoisomerase III, partial [Methylibium sp. YR605].	33.16	380	218	11	40	399	259	622	3e-43	173
rs:WP_013725751	DNA topoisomerase III [Clostridium botulinum].	30.89	437	253	16	55	454	284	708	3e-43	172
rs:WP_008565033	DNA topoisomerase III [Prevotella maculosa].	29.72	424	257	11	18	406	212	629	3e-43	172
rs:WP_003171354	DNA topoisomerase III [Bacillus anthracis].	29.97	387	247	12	77	454	2	373	3e-43	167
rs:WP_011108131	DNA topoisomerase III [Bacteroides thetaiotaomicron].	31.71	369	237	10	31	396	252	608	3e-43	172
tr:N0DXA8_STRPY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.40	414	252	10	52	452	264	658	3e-43	172
rs:WP_008175979	DNA topoisomerase III [Bacillus sp. B14905].	30.83	412	250	11	61	450	269	667	3e-43	172
rs:WP_031587950	DNA topoisomerase III [Lachnospiraceae bacterium P6A3].	31.96	413	240	15	16	392	240	647	3e-43	171
rs:WP_009428925	DNA topoisomerase III [Oribacterium sp. oral taxon 108].	30.19	361	231	8	57	399	286	643	3e-43	171
rs:WP_000115175	DNA topoisomerase III [Bacillus thuringiensis].	30.32	409	257	12	57	454	267	658	3e-43	172
rs:WP_024739084	DNA topoisomerase III [Clostridiales bacterium VE202-16].	31.25	432	257	14	34	450	221	627	3e-43	171
rs:WP_019226534	hypothetical protein [Dehalobacter sp. E1].	32.64	432	259	12	31	442	218	637	3e-43	172
rs:WP_028597698	DNA topoisomerase III [Paenibacillus pasadenensis].	32.48	391	233	10	40	408	234	615	3e-43	172
rs:WP_007721869	MULTISPECIES: DNA topoisomerase III [Carnobacterium].	28.57	413	260	11	58	454	262	655	3e-43	172
rs:WP_031787084	DNA topoisomerase III [Staphylococcus aureus].	28.88	419	276	8	35	450	227	626	3e-43	171
rs:WP_019208345	DNA topoisomerase III [Phocaeicola abscessus].	30.05	426	271	12	23	432	240	654	3e-43	171
rs:WP_047451372	DNA topoisomerase III [Staphylococcus aureus].	28.88	419	276	8	35	450	227	626	3e-43	171
rs:WP_018969030	hypothetical protein [Rubritalea marina].	31.37	424	255	13	40	449	265	666	3e-43	173
tr:T0NZ48_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.76	311	179	3	40	349	234	518	3e-43	170
tr:Q6N2B4_RHOPA	SubName: Full=Complete genome; segment 14/16 {ECO:0000313|EMBL:CAE29577.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CAE29577.1};	32.34	337	204	8	91	408	107	438	3e-43	171
tr:L2L4T1_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.88	365	211	11	102	452	2	346	3e-43	166
rs:WP_039240526	DNA topoisomerase III [Clostridium botulinum].	30.89	437	253	16	55	454	284	708	4e-43	172
rs:WP_006799305	DNA topoisomerase III [Dysgonomonas gadei].	35.63	348	196	11	70	401	260	595	4e-43	171
rs:WP_046495771	hypothetical protein [Syntrophomonas zehnderi].	30.56	373	240	8	58	425	255	613	4e-43	171
rs:WP_026073519	DNA topoisomerase III [Bacillus massiliosenegalensis].	29.26	434	270	12	36	450	244	659	4e-43	171
rs:WP_029655836	MULTISPECIES: DNA topoisomerase, partial [Enterococcus].	33.15	371	210	12	98	452	1	349	4e-43	167
rs:WP_021891241	DNA topoisomerase III, partial [Bacteroides sp. CAG:20].	30.93	375	242	8	37	407	256	617	4e-43	171
rs:WP_040663200	DNA topoisomerase III [Oscillibacter ruminantium].	32.12	411	230	13	47	445	235	608	4e-43	171
rs:WP_037298423	DNA topoisomerase III [Ruminococcus flavefaciens].	32.04	412	245	13	37	443	227	608	4e-43	171
rs:WP_031409354	DNA topoisomerase III [Geobacillus vulcani].	32.20	354	225	7	36	385	245	587	4e-43	171
rs:WP_033010883	DNA topoisomerase III [Geobacillus stearothermophilus].	31.72	372	239	7	36	403	245	605	4e-43	171
rs:WP_008982250	DNA topoisomerase III [Ruminococcaceae bacterium D16].	30.96	407	250	11	47	445	235	618	4e-43	171
rs:WP_000115176	DNA topoisomerase III [Bacillus cereus].	30.32	409	257	12	57	454	267	658	4e-43	171
rs:WP_045369874	DNA topoisomerase III [Enterobacter asburiae].	31.49	416	262	9	31	432	240	646	4e-43	171
rs:WP_029656423	DNA topoisomerase, partial [Enterococcus faecalis].	33.15	371	210	12	98	452	1	349	4e-43	167
rs:WP_032666425	MULTISPECIES: DNA topoisomerase III [Enterobacter].	31.49	416	262	9	31	432	240	646	4e-43	171
rs:WP_039259014	DNA topoisomerase III [Clostridium botulinum].	30.28	436	259	15	46	450	275	696	4e-43	171
rs:WP_010170286	DNA topoisomerase III [Bacillus coahuilensis].	30.46	371	240	5	32	398	228	584	4e-43	171
rs:WP_029658570	DNA topoisomerase, partial [Enterococcus faecalis].	32.13	417	245	12	52	452	115	509	4e-43	170
tr:W7WFC9_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.52	361	210	9	40	383	263	610	4e-43	171
rs:WP_040555026	DNA topoisomerase III [Prevotella multiformis].	30.91	385	249	9	24	396	221	600	4e-43	171
rs:WP_016278733	DNA topoisomerase III [Lachnospiraceae bacterium A4].	30.09	452	256	13	47	446	270	713	5e-43	174
rs:WP_004293951	DNA topoisomerase III [Bacteroides eggerthii].	31.81	371	239	9	30	396	257	617	5e-43	171
rs:WP_022476560	DNA topoisomerase [Clostridium sp. CAG:273].	29.82	389	233	11	47	398	304	689	5e-43	171
rs:WP_004288554	DNA topoisomerase III [Bacteroides eggerthii].	31.81	371	239	9	30	396	257	617	5e-43	171
rs:WP_007364773	DNA topoisomerase III [Porphyromonas uenonis].	34.12	337	208	10	47	375	248	578	5e-43	171
rs:WP_015238851	DNA topoisomerase III [Candidatus Kinetoplastibacterium crithidii].	30.14	438	273	10	28	448	239	660	5e-43	172
rs:WP_025477999	DNA topoisomerase [Enterococcus faecium].	33.53	343	202	10	65	400	47	370	5e-43	167
rs:WP_022072241	DNA topoisomerase III [Clostridium bartlettii CAG:1329].	30.34	379	226	7	54	428	254	598	5e-43	171
rs:WP_034604312	MULTISPECIES: DNA topoisomerase III, partial [Desulfovibrio].	31.00	442	262	10	3	425	216	633	5e-43	171
rs:WP_009490444	DNA topoisomerase III [Catellicoccus marimammalium].	30.05	416	243	13	59	449	269	661	5e-43	171
rs:WP_021940547	DNA topoisomerase III [Bacteroides eggerthii CAG:109].	31.81	371	239	9	30	396	257	617	5e-43	171
rs:WP_044477171	DNA topoisomerase III [Paenibacillus sp. GD11].	29.71	414	247	7	34	435	229	610	5e-43	171
rs:WP_014794498	DNA topoisomerase III [Desulfitobacterium dehalogenans].	31.20	375	240	9	25	393	258	620	5e-43	172
rs:WP_018903490	DNA topoisomerase III [Variovorax paradoxus].	32.07	368	225	11	47	399	275	632	5e-43	173
tr:D4C6M5_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.95	420	252	12	40	445	231	626	5e-43	171
rs:WP_035149399	DNA topoisomerase III [Clostridium tetanomorphum].	30.85	363	209	9	61	399	296	640	5e-43	171
rs:WP_023414868	hypothetical protein [uncultured Thiohalocapsa sp. PB-PSB1].	31.11	389	253	3	59	434	260	646	5e-43	172
rs:WP_044930428	DNA topoisomerase III [Clostridium sp. M62/1].	30.95	420	252	12	40	445	228	623	5e-43	171
rs:WP_029141630	DNA topoisomerase III [Bacillus coagulans].	30.10	392	242	5	36	426	230	590	5e-43	171
rs:WP_005827194	DNA topoisomerase III [Bacteroides uniformis].	31.00	371	243	9	29	396	258	618	5e-43	171
rs:WP_025041234	DNA topoisomerase III [Nitrosospira briensis].	33.50	409	239	16	40	435	255	643	5e-43	172
rs:WP_000838476	DNA topoisomerase III [Staphylococcus argenteus].	28.88	419	276	8	35	450	227	626	5e-43	171
tr:R2B9H1_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.81	415	249	11	52	452	264	658	5e-43	171
rs:WP_013859236	DNA topoisomerase III [Bacillus coagulans].	30.10	392	242	5	36	426	230	590	6e-43	171
rs:WP_009259780	DNA topoisomerase III [Lachnospiraceae bacterium 7_1_58FAA].	32.91	395	227	11	60	445	250	615	6e-43	171
rs:WP_042335867	DNA topoisomerase III [Candidatus Accumulibacter sp. BA-92].	32.15	423	235	13	40	435	255	652	6e-43	172
rs:WP_002569206	DNA topoisomerase III [[Clostridium] bolteae].	31.80	434	252	15	34	450	221	627	6e-43	171
tr:F0F5I7_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.91	385	249	9	24	396	313	692	6e-43	171
rs:WP_026573203	DNA topoisomerase III [Bacillus sp. UNC438CL73TsuS30].	29.98	427	266	12	36	446	244	653	6e-43	171
rs:WP_003347899	DNA topoisomerase III [Bacillus methanolicus].	28.54	417	255	9	36	446	230	609	6e-43	171
rs:WP_032991737	DNA topoisomerase III, partial [Cronobacter dublinensis].	37.23	231	138	2	155	385	1	224	6e-43	164
rs:WP_039257512	DNA topoisomerase III [Clostridium botulinum].	30.05	436	260	15	46	450	275	696	7e-43	171
rs:WP_038880477	DNA topoisomerase III, partial [Vibrio jasicida].	33.33	312	192	5	26	328	238	542	7e-43	170
rs:WP_031915414	DNA topoisomerase III, partial [Staphylococcus aureus].	30.20	351	221	5	35	377	89	423	7e-43	167
rs:WP_003350935	DNA topoisomerase III [Bacillus methanolicus].	28.40	405	249	7	36	434	230	599	7e-43	171
rs:WP_008650257	DNA topoisomerase III [Bacteroides sp. 3_1_23].	30.89	369	240	10	31	396	252	608	7e-43	171
rs:WP_011379758	DNA topoisomerase III [Nitrosospira multiformis].	32.75	397	239	14	40	425	255	634	7e-43	172
rs:WP_028259688	DNA topoisomerase III [Variovorax sp. JGI 0001016-M12].	32.49	354	214	11	47	385	276	619	7e-43	172
rs:WP_018662197	DNA topoisomerase III [Bacillus acidiproducens].	30.66	411	251	8	36	445	230	607	7e-43	171
rs:WP_014118863	DNA topoisomerase III [Oscillibacter valericigenes].	32.10	433	238	14	47	457	234	632	7e-43	171
rs:WP_009880163	DNA topoisomerase III [Bacillus anthracis].	29.97	387	247	12	77	454	2	373	7e-43	166
rs:WP_014079867	DNA topoisomerase [Roseburia hominis].	29.57	443	261	12	47	446	275	709	7e-43	174
rs:WP_043400217	ATP-dependent DNA helicase RecQ [Cystobacter violaceus].	31.79	390	245	8	43	414	259	645	7e-43	174
rs:WP_026564446	DNA topoisomerase III [Bacillus sp. UNC41MFS5].	29.26	434	258	12	36	459	230	624	7e-43	171
rs:WP_011677354	DNA topoisomerase [Oenococcus oeni].	29.17	408	254	12	66	454	278	669	7e-43	171
rs:WP_022477608	DNA topoisomerase [Coraliomargarita sp. CAG:312].	33.14	350	205	8	65	403	278	609	7e-43	172
rs:WP_046112814	DNA topoisomerase III [Aquincola tertiaricarbonis].	34.09	352	194	12	55	385	278	612	7e-43	172
rs:WP_000539255	DNA topoisomerase III [Bacillus cereus].	30.65	398	246	11	59	446	270	647	7e-43	171
rs:WP_012742985	DNA topoisomerase [Eubacterium rectale].	29.78	450	256	11	49	446	272	713	7e-43	173
rs:WP_022292366	DNA topoisomerase [Eubacterium rectale CAG:36].	29.65	452	258	11	47	446	270	713	7e-43	173
rs:WP_006282052	DNA topoisomerase III [Prevotella bryantii].	30.48	397	246	11	18	396	212	596	7e-43	170
rs:WP_017553252	DNA topoisomerase III [Bacillus coagulans].	30.10	392	242	5	36	426	230	590	7e-43	170
tr:A0A0E1MML2_BACAN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.97	387	247	12	77	454	2	373	8e-43	167
tr:X6T0G3_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.24	367	207	12	102	452	2	346	8e-43	166
rs:WP_003366191	DNA topoisomerase III [Clostridium botulinum].	28.89	450	271	16	35	446	260	698	8e-43	171
rs:WP_026640596	DNA topoisomerase III [Bordetella petrii].	33.70	362	211	8	38	385	252	598	8e-43	172
rs:WP_008618622	DNA topoisomerase III [Paraprevotella clara].	31.59	345	228	6	54	396	276	614	8e-43	171
rs:WP_027866328	hypothetical protein [Massilia alkalitolerans].	31.40	414	250	9	33	428	246	643	8e-43	171
rs:WP_021935895	DNA topoisomerase III [Bacteroides sp. CAG:189].	33.64	330	206	9	74	401	267	585	8e-43	170
rs:WP_031922934	DNA topoisomerase III, partial [Staphylococcus aureus].	30.58	363	220	9	96	450	1	339	8e-43	166
tr:D4JPB1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.65	452	258	11	47	446	270	713	8e-43	173
rs:WP_015592305	DNA topoisomerase III [Bacillus sp. 1NLA3E].	28.67	443	280	9	18	457	210	619	8e-43	170
rs:WP_017638522	DNA topoisomerase III [Staphylococcus sp. E463].	29.09	416	269	9	40	450	233	627	8e-43	171
rs:WP_007037046	DNA topoisomerase III [[Clostridium] bolteae].	32.07	421	251	13	37	445	225	622	8e-43	170
rs:WP_042596196	DNA topoisomerase III [Bacillus thuringiensis].	30.65	398	246	11	59	446	270	647	8e-43	171
rs:WP_001575003	MULTISPECIES: DNA topoisomerase III [Staphylococcus].	30.18	381	247	8	55	427	261	630	8e-43	170
rs:WP_033143528	DNA topoisomerase III [Blautia producta].	32.26	403	239	13	56	445	244	625	8e-43	170
rs:WP_020478294	ATP-dependent DNA helicase RecQ [Myxococcus xanthus].	34.24	368	215	10	47	392	295	657	9e-43	174
rs:WP_022129902	DNA topoisomerase III [Bacteroides sp. CAG:530].	30.85	363	237	9	37	396	230	581	9e-43	170
rs:WP_019850806	DNA topoisomerase III [Desulfitobacterium sp. PCE1].	30.93	375	241	9	25	393	258	620	9e-43	171
rs:WP_044796831	DNA topoisomerase I [Bacillus cereus].	29.00	431	281	9	32	454	236	649	9e-43	172
rs:WP_004607961	DNA topoisomerase III [[Clostridium] scindens].	32.22	419	249	13	39	445	227	622	9e-43	170
rs:WP_042257786	DNA topoisomerase, partial [Butyrivibrio proteoclasticus].	30.86	418	239	13	3	392	244	639	9e-43	170
rs:WP_021980997	DNA topoisomerase III [Paraprevotella clara CAG:116].	31.59	345	228	6	54	396	276	614	9e-43	170
rs:WP_031417620	DNA topoisomerase III [Lysinibacillus sphaericus].	28.99	445	269	14	25	455	246	657	9e-43	170
tr:W1WMJ5_9ZZZZ	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ETJ17674.1};	30.34	379	226	7	54	428	254	598	9e-43	170
rs:WP_026683480	DNA topoisomerase III [Bacillus coagulans].	28.88	412	259	6	18	426	210	590	9e-43	170
rs:WP_036866402	DNA topoisomerase III [Prevotella bivia].	32.19	351	218	11	37	375	235	577	9e-43	170
rs:WP_027324472	DNA topoisomerase III [Bacteroides pyogenes].	30.33	389	238	10	31	396	252	630	9e-43	171
rs:WP_032848987	DNA topoisomerase III, partial [Mannheimia haemolytica].	41.46	205	117	2	35	237	244	447	9e-43	167
rs:WP_007884149	DNA topoisomerase III [Roseburia inulinivorans].	32.07	421	251	13	37	445	223	620	9e-43	170
rs:WP_044907652	DNA topoisomerase III [[Clostridium] innocuum].	30.93	430	261	13	34	450	221	627	9e-43	170
rs:WP_022517670	DNA topoisomerase [Roseburia sp. CAG:100].	29.43	435	264	12	47	446	270	696	9e-43	173
rs:WP_047501966	DNA topoisomerase III, partial [Methylibium sp. CF468].	32.72	379	221	11	40	399	259	622	1e-42	171
tr:Q1DEW9_MYXXD	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	34.24	368	215	10	47	392	267	629	1e-42	173
rs:WP_036628384	DNA topoisomerase III [Oscillospiraceae bacterium VE202-24].	33.89	360	215	9	27	377	215	560	1e-42	170
rs:WP_024732370	DNA topoisomerase III [Clostridiales bacterium VE202-14].	33.61	366	220	11	47	392	271	633	1e-42	170
rs:WP_002376294	DNA topoisomerase [Enterococcus faecium].	33.53	343	202	10	65	400	47	370	1e-42	166
rs:WP_014862450	DNA topoisomerase [Enterococcus faecalis].	32.05	415	248	11	52	452	264	658	1e-42	170
rs:WP_034806015	DNA topoisomerase III [Exiguobacterium sp. AB2].	30.28	426	255	11	47	452	255	658	1e-42	170
rs:WP_035566908	DNA topoisomerase III [Hymenobacter sp. IS2118].	28.57	455	273	12	30	446	247	687	1e-42	171
rs:WP_008776282	DNA topoisomerase III [Bacteroides sp. 2_2_4].	30.89	369	240	10	31	396	252	608	1e-42	170
rs:WP_002331394	hypothetical protein [Enterococcus faecalis].	33.24	367	207	12	102	452	2	346	1e-42	166
tr:R3K3Y6_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.24	367	207	12	102	452	2	346	1e-42	166
rs:WP_024997486	DNA topoisomerase III [Bacteroides graminisolvens].	32.48	351	223	9	49	396	270	609	1e-42	170
rs:WP_040205630	DNA topoisomerase III, partial [Klebsiella pneumoniae].	30.66	362	223	7	114	459	1	350	1e-42	167
rs:WP_025115653	DNA topoisomerase III [Lysinibacillus fusiformis].	30.83	412	250	11	61	450	269	667	1e-42	170
tr:W4PIV4_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE19069.1};	30.33	389	238	10	31	396	321	699	1e-42	171
rs:WP_035476679	hypothetical protein [Burkholderia phenoliruptrix].	38.53	231	132	4	31	260	251	472	1e-42	167
rs:WP_039042607	DNA topoisomerase III [Sporosarcina sp. ZBG7A].	31.14	456	259	17	26	454	234	661	1e-42	170
rs:WP_025839347	DNA topoisomerase III [Prevotella scopos].	32.35	405	242	15	18	401	216	609	1e-42	169
rs:WP_042577333	DNA topoisomerase III [Variovorax paradoxus].	31.72	413	255	13	40	437	270	670	1e-42	172
rs:WP_042827078	DNA topoisomerase [Xanthomonas axonopodis].	32.04	412	233	13	40	427	265	653	1e-42	171
tr:D4JA74_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.38	427	256	14	35	445	217	622	1e-42	170
rs:WP_014098426	DNA topoisomerase III [Bacillus coagulans].	28.16	412	262	6	18	426	210	590	1e-42	170
rs:WP_007482184	DNA topoisomerase III [Bacteroides salyersiae].	33.64	330	206	9	74	401	267	585	1e-42	170
rs:WP_005933470	DNA topoisomerase III [Bacteroides salyersiae].	33.64	330	206	9	74	401	267	585	1e-42	170
rs:WP_017550807	DNA topoisomerase III [Bacillus coagulans].	29.97	397	243	6	31	426	228	590	1e-42	170
rs:WP_026828856	DNA topoisomerase III [Exiguobacterium sibiricum].	29.03	434	274	11	34	454	239	651	1e-42	170
rs:WP_005423585	DNA topoisomerase III [[Ruminococcus] obeum].	31.38	427	256	14	35	445	217	622	1e-42	170
rs:WP_021426980	DNA topoisomerase III [Peptoclostridium difficile].	32.70	419	246	13	40	445	228	623	1e-42	169
rs:WP_034410032	DNA topoisomerase III, partial [Derxia gummosa].	31.65	357	220	8	38	385	263	604	1e-42	171
rs:WP_043859178	DNA topoisomerase III, partial [Bacillus subtilis].	33.05	357	220	9	59	410	267	609	1e-42	169
gp:CP009695_24	DNA topoisomerase family protein [Bacillus anthracis]	29.97	387	247	12	77	454	2	373	1e-42	166
rs:WP_009011127	DNA topoisomerase III [Prevotella sp. C561].	32.42	401	236	14	24	401	221	609	2e-42	169
rs:WP_046414281	DNA topoisomerase III [Bacteroides sp. UNK.MGS-13].	30.67	375	243	8	37	407	230	591	2e-42	169
rs:WP_040109448	DNA topoisomerase III [Jeotgalibacillus sp. D5].	29.78	403	253	9	35	426	228	611	2e-42	170
rs:WP_008816736	DNA topoisomerase III [Erysipelotrichaceae bacterium 6_1_45].	30.91	427	256	13	34	445	221	623	2e-42	169
rs:WP_022405198	DNA topoisomerase III [Prevotella sp. CAG:485].	34.76	328	200	9	74	394	267	587	2e-42	169
rs:WP_017172407	hypothetical protein [Xanthomonas axonopodis].	32.04	412	233	13	40	427	265	653	2e-42	171
tr:A0A0D8IWN4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.50	400	231	13	60	445	248	618	2e-42	169
rs:WP_020616278	hypothetical protein [Paenibacillus daejeonensis].	32.38	386	229	10	40	401	234	611	2e-42	170
tr:A0A0D1IX46_BACIU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.05	357	220	9	59	410	267	609	2e-42	169
rs:WP_015867941	DNA topoisomerase III [Variovorax paradoxus].	31.79	368	226	11	47	399	275	632	2e-42	171
rs:WP_018705508	hypothetical protein [Bacillus fordii].	29.06	413	252	9	38	445	232	608	2e-42	169
tr:J9C5L9_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJW95125.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EJW95125.1};	33.06	360	228	9	28	385	255	603	2e-42	169
rs:WP_043712494	ATP-dependent DNA helicase RecQ, partial [Myxococcus fulvus].	32.70	370	218	8	47	392	230	592	2e-42	172
tr:J8GVI6_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.65	398	246	11	59	446	344	721	2e-42	170
gpu:CP011509_1477	DNA topoisomerase III [Archangium gephyra]	32.71	373	231	7	43	398	267	636	2e-42	172
rs:WP_033020754	DNA topoisomerase III [Geobacillus sp. G1w1].	32.20	354	225	7	36	385	245	587	2e-42	169
rs:WP_035275918	DNA topoisomerase III [Desulfobulbus japonicus].	31.30	377	229	9	38	402	258	616	2e-42	170
rs:WP_048340769	DNA topoisomerase [Enterococcus faecium].	33.53	343	202	10	65	400	169	492	2e-42	167
rs:WP_002821023	DNA topoisomerase [Oenococcus oeni].	28.51	449	282	13	29	454	237	669	2e-42	169
rs:WP_036922967	DNA topoisomerase III [Prevotella sp. ICM33].	32.10	405	243	15	18	401	216	609	2e-42	169
rs:WP_013172858	DNA topoisomerase III [[Bacillus] selenitireducens].	29.97	387	247	8	22	396	224	598	2e-42	169
rs:WP_047854825	ATP-dependent DNA helicase RecQ [Archangium gephyra].	32.71	373	231	7	43	398	269	638	2e-42	172
rs:WP_034546490	DNA topoisomerase III [Carnobacterium alterfunditum].	28.36	409	262	11	58	454	263	652	2e-42	169
rs:WP_016147259	DNA topoisomerase III [Butyricicoccus pullicaecorum].	31.37	408	238	10	40	425	228	615	2e-42	169
rs:WP_012959749	DNA topoisomerase III [Bacillus pseudofirmus].	28.47	439	274	12	38	453	246	667	2e-42	169
rs:WP_002824608	DNA topoisomerase [Oenococcus oeni].	28.51	449	282	13	29	454	237	669	2e-42	169
rs:WP_006255133	DNA topoisomerase III [Alloprevotella tannerae].	33.71	353	224	8	51	399	249	595	2e-42	169
rs:WP_036031200	hypothetical protein, partial [Burkholderia gladioli].	33.43	344	214	6	40	377	160	494	2e-42	167
rs:WP_002818003	DNA topoisomerase [Oenococcus oeni].	28.70	453	276	13	29	454	237	669	2e-42	169
rs:WP_019721174	DNA topoisomerase III [Bacillus coagulans].	29.85	392	243	5	36	426	230	590	2e-42	169
tr:A0A0F5R0A7_9BACL	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KKC46418.1};	31.33	383	231	8	40	398	234	608	2e-42	170
rs:WP_036952801	DNA topoisomerase, partial [Pseudobutyrivibrio ruminis].	30.57	435	258	15	47	446	272	697	2e-42	169
tr:L8PRE1_BACIU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.05	357	220	9	59	410	297	639	2e-42	169
rs:WP_018589388	DNA topoisomerase III [Terrisporobacter glycolicus].	31.47	375	213	8	61	428	262	599	2e-42	169
rs:WP_003250827	DNA topoisomerase III [Geobacillus thermoglucosidasius].	29.70	431	269	12	36	450	245	657	2e-42	169
rs:WP_021633201	DNA topoisomerase [Clostridium sp. ATCC BAA-442].	32.18	435	238	15	40	451	227	627	2e-42	169
rs:WP_002823296	DNA topoisomerase [Oenococcus oeni].	28.51	449	282	13	29	454	237	669	2e-42	169
rs:WP_020878368	DNA topoisomerase III [Desulfococcus multivorans].	27.63	409	266	8	47	446	272	659	2e-42	171
rs:WP_029055860	DNA topoisomerase III [Staphylococcus sp. URHA0057].	28.74	421	274	9	35	450	228	627	2e-42	169
tr:T4NA99_PEPDI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.02	432	268	12	31	451	237	649	3e-42	169
rs:WP_032807128	topoisomerase I [Oenococcus oeni].	28.51	449	282	13	29	454	237	669	3e-42	169
rs:WP_031826156	DNA topoisomerase III, partial [Staphylococcus aureus].	30.00	370	227	9	89	450	7	352	3e-42	166
rs:WP_033843831	DNA topoisomerase III [Geobacillus subterraneus].	32.20	354	225	7	36	385	245	587	3e-42	169
rs:WP_036885935	DNA topoisomerase III [Prevotella bivia].	31.91	351	219	11	37	375	235	577	3e-42	168
tr:W8YT76_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.33	383	231	8	40	398	234	608	3e-42	170
rs:WP_047527129	DNA topoisomerase III [Staphylococcus aureus].	28.64	419	277	8	35	450	227	626	3e-42	169
rs:WP_025191329	DNA topoisomerase, partial [Enterococcus faecalis].	29.40	398	251	9	53	434	146	529	3e-42	168
rs:WP_047431125	DNA topoisomerase III [Staphylococcus aureus].	28.40	419	278	8	35	450	227	626	3e-42	169
tr:R3JUZ9_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.40	398	251	9	53	434	146	529	3e-42	168
rs:WP_022978745	DNA topoisomerase III [Ideonella sp. B508-1].	32.70	370	206	13	40	385	264	614	3e-42	170
rs:WP_045670938	DNA topoisomerase III [Paenibacillus beijingensis].	31.37	373	215	7	73	428	270	618	3e-42	169
rs:WP_027400099	DNA topoisomerase III [Anaerovorax odorimutans].	28.36	409	268	8	35	428	226	624	3e-42	169
rs:WP_019364747	hypothetical protein [Pseudomonas luteola].	29.56	433	277	13	38	452	243	665	3e-42	169
rs:WP_034301545	DNA topoisomerase III [Bacillus sp. FJAT-14515].	28.11	434	279	12	36	453	243	659	3e-42	169
rs:WP_040603203	DNA topoisomerase III [Paraprevotella xylaniphila].	30.87	366	243	7	54	415	276	635	3e-42	169
rs:WP_039255204	DNA topoisomerase III [Clostridium novyi].	29.34	426	256	15	55	446	284	698	3e-42	169
rs:WP_024028720	DNA topoisomerase III [Bacillus vireti].	29.63	432	262	13	36	446	244	654	3e-42	169
rs:WP_016220887	DNA topoisomerase III [Dorea sp. 5-2].	33.01	418	247	15	40	445	228	624	3e-42	169
rs:WP_004336120	DNA topoisomerase III [Prevotella bivia].	31.25	352	220	10	37	375	235	577	3e-42	168
tr:A0A0E1SW33_HAEIF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	36.05	233	141	2	36	268	260	484	3e-42	167
rs:WP_036861766	DNA topoisomerase III [Prevotella bivia].	35.90	312	177	12	79	375	274	577	3e-42	168
tr:D6E5U2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.58	453	257	12	47	446	270	713	3e-42	171
rs:WP_031811092	DNA topoisomerase III, partial [Staphylococcus aureus].	30.00	370	227	9	89	450	4	349	4e-42	166
rs:WP_046532154	DNA topoisomerase III, partial [Candidatus Accumulibacter phosphatis].	31.82	418	243	11	40	435	255	652	4e-42	170
rs:WP_002107335	DNA topoisomerase III [Bacillus cereus].	30.32	409	257	11	57	454	268	659	4e-42	169
rs:WP_027859721	DNA topoisomerase III [Marinobacterium jannaschii].	27.57	428	281	9	35	459	248	649	4e-42	168
rs:WP_016085280	DNA topoisomerase III [Bacillus cereus].	30.73	423	257	12	51	454	261	666	4e-42	169
rs:WP_022168305	DNA topoisomerase [Clostridium sp. CAG:221].	30.37	428	257	13	40	452	256	657	4e-42	169
rs:WP_045665981	hypothetical protein, partial [Pseudomonas sp. BRH_c35].	33.15	368	226	11	38	393	240	599	4e-42	168
rs:WP_018977667	hypothetical protein [Saccharibacillus kuerlensis].	28.95	449	274	11	38	449	246	686	4e-42	169
rs:WP_035314731	DNA topoisomerase III [Brochothrix campestris].	31.58	361	226	6	43	397	238	583	4e-42	168
tr:F3QYD9_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EGG50486.1};	30.87	366	243	7	54	415	309	668	4e-42	169
rs:WP_026382163	DNA topoisomerase [Achromobacter xylosoxidans].	32.46	382	223	9	36	396	248	615	4e-42	169
rs:WP_009988109	DNA topoisomerase III [Ruminococcus flavefaciens].	30.75	413	248	13	37	443	227	607	4e-42	168
rs:WP_016308801	DNA topoisomerase III [Enterorhabdus caecimuris].	32.51	403	240	9	40	431	245	626	4e-42	168
rs:WP_044910184	hypothetical protein, partial [Lachnospiraceae bacterium MC2017].	32.88	371	225	14	41	396	263	624	4e-42	168
rs:WP_032822357	topoisomerase I [Oenococcus oeni].	28.51	449	282	13	29	454	237	669	4e-42	168
rs:WP_040223245	DNA topoisomerase III, partial [Klebsiella pneumoniae].	36.77	291	173	5	27	313	82	365	4e-42	164
rs:WP_013264979	DNA topoisomerase III [Prevotella melaninogenica].	31.60	405	245	14	18	401	216	609	4e-42	168
rs:WP_002588973	DNA topoisomerase III, partial [[Clostridium] clostridioforme].	31.86	430	248	15	34	445	141	543	5e-42	167
rs:WP_006951164	DNA topoisomerase III [Prevotella micans].	31.94	360	228	11	37	387	230	581	5e-42	167
rs:WP_002570999	DNA topoisomerase III [[Clostridium] bolteae].	30.79	432	259	14	34	450	223	629	5e-42	168
rs:WP_004361160	DNA topoisomerase III [Prevotella melaninogenica].	31.85	405	244	15	18	401	216	609	5e-42	167
rs:WP_034818146	DNA topoisomerase III [Exiguobacterium alkaliphilum].	30.05	426	256	11	47	452	255	658	5e-42	168
rs:WP_031580844	DNA topoisomerase III [Lachnospiraceae bacterium AC2028].	30.11	445	260	15	3	401	229	668	5e-42	168
rs:WP_008408467	DNA topoisomerase III [Bacillus isronensis].	29.57	443	262	11	36	450	244	664	5e-42	168
rs:WP_036854117	DNA topoisomerase III [Prevotella denticola].	29.63	405	265	10	24	413	221	620	5e-42	167
tr:D4X4C7_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.54	378	228	9	36	396	247	614	5e-42	169
rs:WP_039882454	MULTISPECIES: DNA topoisomerase [Achromobacter].	32.54	378	228	9	36	396	248	615	5e-42	169
rs:WP_016627352	DNA topoisomerase [Enterococcus faecalis].	29.40	398	251	9	53	434	265	648	5e-42	168
rs:WP_007201633	DNA topoisomerase III [Fictibacillus macauensis].	29.95	394	245	6	36	428	230	593	5e-42	168
rs:WP_022238218	DNA topoisomerase [Clostridium sp. CAG:343].	31.82	374	224	13	47	392	19	389	5e-42	164
rs:WP_033646108	hypothetical protein [Bacillus anthracis].	29.72	387	248	12	77	454	2	373	5e-42	164
rs:WP_039972867	DNA topoisomerase III [Bacteroides pyogenes].	30.33	389	238	10	31	396	252	630	5e-42	169
rs:WP_009536236	DNA topoisomerase III [Oribacterium asaccharolyticum].	30.66	362	227	8	59	399	288	646	6e-42	167
rs:WP_006441522	DNA topoisomerase III [[Clostridium] hylemonae].	31.64	414	242	13	3	392	245	641	6e-42	168
rs:WP_016273003	DNA topoisomerase III [Bacteroides uniformis].	30.46	371	245	9	29	396	258	618	6e-42	168
tr:U2CVP4_9BACE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERI88620.1};	30.33	389	238	10	31	396	268	646	6e-42	169
rs:WP_034759339	DNA topoisomerase III [Bacillus vietnamensis].	27.23	437	281	10	36	453	244	662	6e-42	168
rs:WP_016303791	DNA topoisomerase III [Lachnospiraceae bacterium A2].	31.16	398	257	7	56	449	245	629	6e-42	168
rs:WP_013671195	DNA topoisomerase III [Prevotella denticola].	30.64	408	257	12	24	413	221	620	6e-42	167
rs:WP_041311293	hypothetical protein, partial [Sebaldella termitidis].	30.90	424	253	11	24	430	228	628	6e-42	167
rs:WP_011189858	DNA topoisomerase III [Desulfotalea psychrophila].	31.02	374	233	11	22	385	243	601	6e-42	169
rs:WP_007862391	DNA topoisomerase III [[Clostridium] citroniae].	31.86	430	248	15	34	445	221	623	6e-42	168
rs:WP_036812954	DNA topoisomerase III [Polaromonas sp. CG9_12].	30.41	434	245	13	40	430	268	687	6e-42	170
rs:WP_022510519	DNA topoisomerase [Prevotella sp. CAG:617].	31.43	385	245	10	18	396	215	586	6e-42	167
rs:WP_002479576	DNA topoisomerase III [Staphylococcus simulans].	28.40	426	269	9	35	450	227	626	6e-42	168
rs:WP_021671158	DNA topoisomerase III [Prevotella sp. F0091].	32.10	405	243	15	18	401	216	609	6e-42	167
rs:WP_016083876	DNA topoisomerase III [Bacillus cereus].	30.59	425	257	12	51	454	261	668	7e-42	168
rs:WP_012369865	DNA topoisomerase III [Exiguobacterium sibiricum].	30.63	431	259	13	40	454	245	651	7e-42	167
rs:WP_047941734	DNA topoisomerase III [Bacillus circulans].	28.94	432	247	12	18	434	210	596	7e-42	167
rs:WP_033126088	DNA topoisomerase III [Eubacterium sp. ER2].	30.91	427	258	14	35	445	217	622	7e-42	167
rs:WP_025487928	DNA topoisomerase III [Clostridiales bacterium VE202-27].	31.57	434	253	15	34	450	221	627	7e-42	167
tr:D3AGG1_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.79	406	243	10	40	425	233	620	7e-42	167
tr:E8REX8_DESPD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.61	363	209	9	56	405	276	619	7e-42	169
rs:WP_004353362	DNA topoisomerase III [Prevotella denticola].	30.64	408	257	12	24	413	221	620	7e-42	167
rs:WP_037589019	DNA topoisomerase III [Staphylococcus aureus].	31.69	385	223	13	79	450	270	627	7e-42	167
rs:WP_002589130	DNA topoisomerase III [[Clostridium] clostridioforme].	31.86	430	248	15	34	445	221	623	7e-42	167
rs:WP_028249919	DNA topoisomerase III [Variovorax sp. URHB0020].	32.77	354	215	10	47	385	275	620	7e-42	170
rs:WP_010830988	DNA topoisomerase III [Enterococcus faecalis].	29.40	398	251	9	53	434	265	648	7e-42	167
rs:WP_000320658	hypothetical protein, partial [Vibrio cholerae].	40.09	222	126	1	164	385	1	215	8e-42	160
rs:WP_016626025	DNA topoisomerase [Enterococcus faecalis].	29.40	398	251	9	53	434	265	648	8e-42	167
rs:WP_002571033	MULTISPECIES: DNA topoisomerase III [Clostridiales].	30.79	406	243	10	40	425	231	618	8e-42	167
rs:WP_043770622	DNA topoisomerase III [Desulfobulbus propionicus].	34.40	343	193	9	56	385	288	611	8e-42	169
rs:WP_014824222	DNA topoisomerase III [Solibacillus silvestris].	29.35	443	263	11	36	450	244	664	8e-42	167
rs:WP_023014977	DNA topoisomerase III [Staphylococcus simulans].	28.40	426	269	9	35	450	227	626	8e-42	167
rs:WP_006450818	topoisomerase IA, partial [Xanthomonas gardneri].	37.35	249	144	5	74	315	3	246	8e-42	159
rs:WP_017694259	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	31.25	416	263	9	31	432	240	646	9e-42	167
rs:WP_022628548	DNA topoisomerase III [Bacillus marmarensis].	28.47	439	274	12	38	453	246	667	9e-42	167
rs:WP_036781770	DNA topoisomerase III [Pontibacillus chungwhensis].	27.87	409	263	11	59	454	270	659	9e-42	167
rs:WP_016289907	DNA topoisomerase III [Lachnospiraceae bacterium 28-4].	31.57	415	257	11	39	445	229	624	9e-42	167
rs:WP_031642429	MULTISPECIES: hypothetical protein [Listeria].	29.41	408	253	12	56	449	267	653	9e-42	167
rs:WP_004798049	DNA topoisomerase III [[Eubacterium] dolichum].	30.79	432	259	14	34	450	224	630	9e-42	167
rs:WP_033801728	DNA topoisomerase III, partial [Escherichia coli].	34.08	267	171	2	37	302	245	507	1e-41	166
rs:WP_018108421	DNA topoisomerase III [Bacteroides propionicifaciens].	29.74	380	255	8	18	396	212	580	1e-41	167
rs:WP_025577806	DNA topoisomerase III [Blautia wexlerae].	31.83	421	252	13	37	445	227	624	1e-41	167
rs:WP_048012772	DNA topoisomerase III [Bacillus marisflavi].	28.15	437	278	11	36	453	244	663	1e-41	167
tr:R9M7W1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.96	363	229	8	40	396	228	578	1e-41	167
rs:WP_020373506	hypothetical protein [Sulfobacillus thermosulfidooxidans].	30.39	441	260	13	18	446	211	616	1e-41	167
rs:WP_022411924	DNA topoisomerase III [Ruminococcus sp. CAG:330].	31.63	411	253	12	40	444	233	621	1e-41	167
rs:WP_009130680	DNA topoisomerase III [Bacteroides oleiciplenus].	29.43	367	246	8	36	396	258	617	1e-41	167
rs:WP_013041960	DNA topoisomerase III [Coraliomargarita akajimensis].	32.71	376	221	11	40	401	263	620	1e-41	168
rs:WP_048003641	DNA topoisomerase III [Bacillus marisflavi].	28.15	437	278	11	36	453	244	663	1e-41	167
rs:WP_034567039	DNA topoisomerase III [Clostridiales bacterium VE202-03].	30.79	432	259	14	34	450	221	627	1e-41	167
rs:WP_022827355	DNA topoisomerase III [Flavobacterium antarcticum].	30.19	424	261	13	38	446	231	634	1e-41	167
rs:WP_040654648	DNA topoisomerase III [Oscillibacter sp. 1-3].	31.96	363	229	8	40	396	230	580	1e-41	167
rs:WP_004313571	MULTISPECIES: DNA topoisomerase III [Bacteroides].	31.17	369	239	10	31	396	253	609	1e-41	167
rs:WP_027424895	DNA topoisomerase III [Lachnospiraceae bacterium NC2004].	29.83	419	247	11	1	392	245	643	1e-41	167
rs:WP_005334803	DNA topoisomerase III [Dorea formicigenerans].	30.91	427	258	14	35	445	217	622	1e-41	167
rs:WP_034543388	DNA topoisomerase III, partial [Bacteroides pyogenes].	30.56	373	229	9	47	396	265	630	1e-41	167
gp:CP006744_95	DNA topoisomerase [Bacillus anthracis str. SVA11]	29.72	387	248	12	77	454	2	373	1e-41	164
rs:WP_023467640	DNA topoisomerase III [Exiguobacterium sp. MH3].	29.98	427	267	11	40	454	245	651	1e-41	167
rs:WP_009298985	MULTISPECIES: DNA topoisomerase III [Clostridiales].	30.79	432	259	14	34	450	221	627	1e-41	167
rs:WP_000063790	DNA topoisomerase [Bacillus cereus].	30.70	443	269	13	32	455	242	665	1e-41	167
rs:WP_008024816	MULTISPECIES: DNA topoisomerase III [Bacteroides].	31.17	369	239	10	31	396	253	609	1e-41	167
rs:WP_013544274	DNA topoisomerase III [Variovorax paradoxus].	31.77	406	250	12	47	437	278	671	1e-41	169
rs:WP_022543364	DNA topoisomerase III [Bacillus infantis].	28.93	401	253	6	36	434	230	600	1e-41	167
rs:WP_042889025	DNA topoisomerase, partial [Enterococcus faecalis].	32.42	364	212	11	98	447	1	344	1e-41	162
rs:WP_003497037	DNA topoisomerase 3 [[Clostridium] symbiosum].	29.23	390	231	9	56	424	261	626	1e-41	167
rs:WP_007883189	DNA topoisomerase III [Roseburia inulinivorans].	32.48	431	244	15	27	445	214	609	1e-41	167
rs:WP_035398234	DNA topoisomerase III [Exiguobacterium sp. OS-77].	29.98	427	267	11	40	454	245	651	1e-41	167
rs:WP_009038766	DNA topoisomerase III [Bacteroides sp. D22].	31.17	369	239	10	31	396	253	609	1e-41	167
rs:WP_044932415	DNA topoisomerase III [Faecalitalea cylindroides].	31.15	427	257	14	35	445	217	622	1e-41	167
rs:WP_025491675	DNA topoisomerase III, partial [Clostridiales bacterium VE202-27].	30.70	430	262	13	34	450	190	596	1e-41	167
rs:WP_005833152	MULTISPECIES: DNA topoisomerase III [Bacteroides].	30.46	371	245	9	29	396	258	618	1e-41	167
rs:WP_008143492	DNA topoisomerase III [Bacteroides coprophilus].	30.53	357	238	7	41	396	268	615	1e-41	167
rs:WP_002205096	DNA topoisomerase I [Bacillus cereus].	28.77	431	282	9	32	454	236	649	1e-41	168
rs:WP_022277691	DNA topoisomerase III [Bacteroides coprophilus CAG:333].	30.53	357	238	7	41	396	268	615	1e-41	167
tr:Q2B0Q7_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	32.06	340	221	6	36	371	246	579	1e-41	166
rs:WP_025190821	DNA topoisomerase, partial [Enterococcus faecalis].	29.15	398	252	9	53	434	146	529	1e-41	166
rs:WP_013400955	MULTISPECIES: DNA topoisomerase III [Geobacillus].	29.14	429	274	11	36	450	245	657	1e-41	167
rs:WP_043756124	DNA topoisomerase III [Thiorhodococcus sp. AK35].	28.80	434	282	8	38	446	234	665	1e-41	168
rs:WP_042108034	DNA topoisomerase III, partial [Escherichia coli].	40.20	199	117	2	36	234	251	447	2e-41	164
rs:WP_042692623	DNA topoisomerase III, partial [Azospirillum sp. B506].	32.42	330	197	9	67	374	232	557	2e-41	166
rs:WP_003505019	DNA topoisomerase III [[Clostridium] symbiosum].	31.49	362	235	6	40	397	230	582	2e-41	167
rs:WP_026320152	DNA topoisomerase III [Bacteroides barnesiae].	31.11	360	233	10	41	396	263	611	2e-41	167
rs:WP_013648723	DNA topoisomerase III [Nitrosomonas sp. AL212].	31.20	391	248	10	40	421	255	633	2e-41	168
rs:WP_000604074	DNA topoisomerase III [Salmonella enterica].	27.23	415	275	6	37	432	247	653	2e-41	167
rs:WP_047345337	DNA topoisomerase III [Enterobacter sp. GN03164].	27.23	415	275	6	37	432	247	653	2e-41	167
rs:WP_037288732	DNA topoisomerase III [Saccharibacillus sacchari].	28.16	451	278	9	38	449	246	689	2e-41	167
tr:W4PUM3_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE22789.1};	30.56	373	229	9	47	396	280	645	2e-41	167
rs:WP_040782654	DNA topoisomerase III [Marvinbryantia formatexigens].	32.37	346	215	8	47	385	235	568	2e-41	166
tr:A0A061PB57_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.30	409	250	14	57	454	17	405	2e-41	164
rs:WP_007045777	DNA topoisomerase III [Subdoligranulum variabile].	31.02	432	258	14	34	450	224	630	2e-41	166
rs:WP_040103605	DNA topoisomerase III [Paenibacillus polymyxa].	30.48	374	232	9	24	385	232	589	2e-41	166
rs:WP_027446336	DNA topoisomerase III [Pontibacillus marinus].	28.19	408	261	10	59	454	270	657	2e-41	166
rs:WP_016219336	DNA topoisomerase III [Dorea sp. 5-2].	31.19	420	253	11	40	445	228	625	2e-41	166
tr:C6LDA7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	32.37	346	215	8	47	385	240	573	2e-41	166
rs:WP_038530696	DNA topoisomerase III [Azospirillum brasilense].	33.43	341	198	10	67	385	258	591	2e-41	167
tr:A0A0D8IXC4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.68	427	257	13	34	445	221	623	2e-41	166
rs:WP_044164756	DNA topoisomerase III [Bacteroides reticulotermitis].	30.36	359	240	7	47	401	270	622	2e-41	166
rs:WP_021388553	DNA topoisomerase III [Peptoclostridium difficile].	32.24	428	236	13	40	445	228	623	2e-41	166
rs:WP_031929814	DNA topoisomerase, partial [Staphylococcus aureus].	31.78	409	245	11	52	446	120	508	2e-41	165
rs:WP_010287696	DNA topoisomerase III [Kurthia massiliensis].	32.52	409	239	14	58	452	267	652	2e-41	166
rs:WP_022339504	DNA topoisomerase III [Bacteroides sp. CAG:714].	31.11	360	233	10	41	396	309	657	2e-41	167
rs:WP_034229460	DNA topoisomerase III [Lachnospiraceae bacterium 3-1].	31.49	416	254	12	40	445	230	624	2e-41	166
rs:WP_036668036	topoisomerase I, partial [Pediococcus acidilactici].	31.58	380	227	10	33	397	46	407	2e-41	165
rs:WP_009905259	DNA topoisomerase III [Peptoclostridium difficile].	33.52	364	225	9	40	396	228	581	2e-41	166
rs:WP_026977380	DNA topoisomerase III [Flavobacterium tegetincola].	30.52	367	232	9	38	399	231	579	2e-41	167
rs:WP_002587416	DNA topoisomerase III [[Clostridium] clostridioforme].	30.07	419	258	11	40	445	230	626	2e-41	166
rs:WP_004070731	DNA topoisomerase III [Clostridium sp. ASF502].	29.20	411	263	9	40	439	228	621	2e-41	166
tr:D6D8L2_9BACE	SubName: Full=Bacteroides xylanisolvens XB1A draft genome {ECO:0000313|EMBL:CBK66357.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBK66357.1};	31.17	369	239	10	31	396	253	609	2e-41	166
tr:L3QI54_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	38.84	242	138	4	29	268	232	465	2e-41	164
rs:WP_046298229	DNA topoisomerase III [Verrucomicrobia bacterium IMCC26134].	32.25	369	226	9	36	385	251	614	2e-41	168
rs:WP_025831777	DNA topoisomerase III [Bacteroides stercorirosoris].	28.96	366	249	7	36	396	258	617	2e-41	166
rs:WP_047390973	DNA topoisomerase III [Exiguobacterium sp. ZWU0009].	29.74	427	268	11	40	454	245	651	2e-41	166
rs:WP_032732402	DNA topoisomerase III, partial [Bacillus subtilis].	33.04	339	211	7	59	392	267	594	2e-41	166
rs:WP_022780297	DNA topoisomerase III [Lachnospiraceae bacterium NK4A136].	29.77	430	243	15	3	392	245	655	2e-41	166
tr:R9II52_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.49	416	254	12	40	445	228	622	2e-41	166
rs:WP_047763363	DNA topoisomerase III, partial [Kiloniella spongiae].	33.15	368	206	13	40	377	232	589	2e-41	166
rs:WP_013855353	DNA topoisomerase III [Lactobacillus kefiranofaciens].	33.16	377	225	11	33	397	241	602	2e-41	166
rs:WP_012345266	DNA topoisomerase III [Leptothrix cholodnii].	32.42	364	197	10	54	385	276	622	3e-41	167
rs:WP_007828684	DNA topoisomerase III [Variovorax sp. CF313].	32.07	368	227	10	47	399	278	637	3e-41	168
rs:WP_029341148	DNA topoisomerase III [Exiguobacterium acetylicum].	29.74	427	268	11	40	454	245	651	3e-41	166
rs:WP_025906799	DNA topoisomerase III [Staphylococcus sciuri].	31.69	385	223	13	79	450	270	627	3e-41	166
rs:WP_009534223	DNA topoisomerase III [Oribacterium parvum].	31.04	364	227	9	59	401	288	648	3e-41	166
rs:WP_045481397	DNA topoisomerase III [Bacillus sp. TS-2].	30.85	402	260	7	38	435	235	622	3e-41	166
rs:WP_036057673	hypothetical protein, partial [Burkholderia mallei].	35.04	351	201	9	40	378	240	575	3e-41	165
rs:WP_015245972	DNA topoisomerase III [Singulisphaera acidiphila].	33.58	411	240	15	40	446	234	615	3e-41	167
rs:WP_002596245	DNA topoisomerase III [[Clostridium] clostridioforme].	30.66	437	263	12	23	445	211	621	3e-41	166
rs:WP_028977379	DNA topoisomerase III [Sporolactobacillus terrae].	28.75	393	243	7	38	426	233	592	3e-41	166
rs:WP_010815313	DNA topoisomerase III [Enterococcus faecalis].	29.95	424	275	7	40	449	229	644	3e-41	166
rs:WP_013439876	DNA topoisomerase [Lactobacillus delbrueckii].	31.55	412	247	13	57	454	269	659	3e-41	166
rs:WP_021979153	DNA topoisomerase [Clostridium sp. CAG:793].	29.01	393	252	12	22	398	268	649	3e-41	165
rs:WP_016359756	MULTISPECIES: DNA topoisomerase III [Clostridiales].	32.21	357	200	11	72	392	310	660	3e-41	166
rs:WP_032823667	topoisomerase I [Oenococcus oeni].	28.29	449	283	13	29	454	237	669	3e-41	166
rs:WP_044119591	DNA topoisomerase, partial [Staphylococcus aureus].	31.78	409	245	11	52	446	148	536	3e-41	164
rs:WP_035185010	DNA topoisomerase III [Bacillus coagulans].	29.72	397	244	6	31	426	228	590	3e-41	166
rs:WP_035288127	DNA topoisomerase III [Clostridium sp. KNHs214].	31.13	363	227	9	61	408	297	651	3e-41	166
rs:WP_004054601	DNA topoisomerase III [Eubacterium plexicaudatum].	29.20	411	263	9	40	439	228	621	3e-41	166
rs:WP_009558242	DNA topoisomerase [Lactobacillus equicursoris].	32.85	414	233	15	59	454	271	657	3e-41	166
rs:WP_006059585	DNA topoisomerase III [Holdemania filiformis].	30.56	432	260	14	34	450	221	627	4e-41	166
rs:WP_040900160	DNA topoisomerase III, partial [Verrucomicrobiae bacterium DG1235].	33.51	367	210	11	47	396	262	611	4e-41	167
rs:WP_010027006	DNA topoisomerase III [Sporolactobacillus inulinus].	28.75	393	243	7	38	426	233	592	4e-41	166
rs:WP_002595170	DNA topoisomerase III [[Clostridium] clostridioforme].	31.73	416	255	12	39	445	229	624	4e-41	166
rs:WP_038323548	DNA topoisomerase III [bacterium MS4].	31.59	421	235	15	39	445	227	608	4e-41	165
tr:E2CSK1_9RHOB	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	33.33	363	223	7	37	385	230	587	4e-41	165
rs:WP_002586545	DNA topoisomerase III [[Clostridium] clostridioforme].	30.58	412	244	10	40	429	228	619	4e-41	166
rs:WP_002576342	MULTISPECIES: DNA topoisomerase III [Lachnospiraceae].	30.60	415	257	10	37	439	225	620	4e-41	166
rs:WP_036125316	MULTISPECIES: DNA topoisomerase III [Lysinibacillus].	29.93	411	256	10	61	450	269	668	4e-41	166
rs:WP_016317940	DNA topoisomerase III [Anaerotruncus sp. G3(2012)].	32.97	364	224	9	40	396	228	578	4e-41	165
rs:WP_016284646	DNA topoisomerase III [Lachnospiraceae bacterium A4].	29.61	412	260	10	40	439	228	621	4e-41	166
rs:WP_028901949	DNA topoisomerase III [Prevotella corporis].	31.94	407	226	15	37	402	235	631	4e-41	165
rs:WP_040581963	hypothetical protein [Sedimentibacter sp. B4].	28.88	419	269	9	47	450	240	644	4e-41	166
rs:WP_002595835	DNA topoisomerase III [[Clostridium] clostridioforme].	30.56	432	260	14	34	450	224	630	4e-41	165
rs:WP_036146170	DNA topoisomerase III [Lysinibacillus fusiformis].	29.93	411	256	10	61	450	269	668	4e-41	166
tr:W0WJX7_PSEAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	37.62	210	127	2	61	268	267	474	4e-41	163
tr:D4L9E3_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.78	428	256	14	31	445	129	533	4e-41	165
rs:WP_036803215	hypothetical protein [Pontibacillus halophilus].	27.96	422	286	10	40	454	240	650	4e-41	165
tr:B5JFY2_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.51	367	210	11	47	396	261	610	4e-41	167
rs:WP_028784638	DNA topoisomerase III [Thalassobacillus devorans].	29.30	413	254	13	58	454	269	659	4e-41	165
tr:A0A059N3S6_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.50	360	209	11	102	447	2	341	4e-41	160
rs:WP_031413506	DNA topoisomerase III [Brevibacillus laterosporus].	29.86	432	283	9	36	454	244	668	4e-41	166
rs:WP_008459746	DNA topoisomerase [Lactobacillus equicursoris].	32.35	408	243	12	59	454	271	657	4e-41	165
rs:WP_002592896	DNA topoisomerase III [[Clostridium] clostridioforme].	31.87	433	253	16	34	450	224	630	4e-41	165
rs:WP_046180764	hypothetical protein [Domibacillus sp. PAMC 80007].	28.37	423	276	9	36	450	247	650	5e-41	165
tr:E2SL06_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.56	432	260	14	34	450	221	627	5e-41	165
rs:WP_038182308	DNA topoisomerase III [Viridibacillus arenosi].	30.33	422	265	11	42	452	253	656	5e-41	165
rs:WP_025579750	DNA topoisomerase III [Blautia wexlerae].	31.49	416	255	10	40	445	228	623	5e-41	165
rs:WP_013555135	DNA topoisomerase [Bacillus thuringiensis].	28.31	438	277	15	35	454	149	567	5e-41	165
rs:WP_009124378	DNA topoisomerase III [Bacteroides fluxus].	30.83	373	243	9	29	396	258	620	5e-41	165
tr:F6IW93_LACPE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.65	376	232	9	33	397	241	602	5e-41	165
rs:WP_025896327	topoisomerase I, partial [Lactobacillus delbrueckii].	31.31	412	248	13	57	454	269	659	5e-41	165
rs:WP_027439694	DNA topoisomerase III [Lachnospiraceae bacterium AC2031].	31.68	363	215	10	60	392	294	653	5e-41	165
rs:WP_024858731	DNA topoisomerase III [Ruminococcus albus].	30.45	404	243	12	35	429	226	600	5e-41	165
rs:WP_041240562	hypothetical protein, partial [Gordonibacter pamelaeae].	33.17	410	239	12	59	445	247	644	5e-41	165
rs:WP_016301096	hypothetical protein [Lachnospiraceae bacterium COE1].	27.11	391	248	8	66	449	150	510	5e-41	164
rs:WP_016220727	DNA topoisomerase III [Dorea sp. 5-2].	28.95	411	264	9	40	439	228	621	5e-41	165
rs:WP_027428651	DNA topoisomerase III [Lachnospiraceae bacterium AD3010].	31.25	400	256	9	32	425	221	607	6e-41	165
rs:WP_006882087	MULTISPECIES: topoisomerase [Enterobacteriaceae].	27.23	415	275	6	37	432	247	653	6e-41	165
rs:WP_036862877	DNA topoisomerase III [Prevotella melaninogenica].	31.85	405	244	15	18	401	216	609	6e-41	164
tr:D4M0W5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.56	432	260	14	34	450	224	630	6e-41	165
tr:F0NX69_LACHH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.63	377	227	10	33	397	35	396	6e-41	163
tr:I7B516_PSEPT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	40.58	207	120	2	36	240	241	446	6e-41	162
rs:WP_003336735	DNA topoisomerase III [Brevibacillus laterosporus].	29.47	431	286	9	36	454	244	668	6e-41	165
rs:WP_046502101	DNA topoisomerase III, partial [Kiloniella sp. P1-1].	32.61	368	208	13	40	377	232	589	6e-41	165
rs:WP_027642634	DNA topoisomerase III [[Clostridium] clostridioforme].	29.90	418	259	11	40	445	228	623	6e-41	165
rs:WP_024549111	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	27.23	415	275	6	37	432	247	653	7e-41	165
rs:WP_012656100	DNA topoisomerase III [Macrococcus caseolyticus].	28.42	387	261	4	18	401	210	583	7e-41	165
rs:WP_044963946	DNA topoisomerase III [Clostridiaceae bacterium MS3].	31.93	357	201	11	72	392	310	660	7e-41	165
rs:WP_029471610	DNA topoisomerase III [Clostridiales bacterium VE202-06].	30.91	427	258	14	35	445	217	622	8e-41	164
rs:WP_009148607	DNA topoisomerase III [Thiorhodovibrio sp. 970].	29.43	384	264	4	36	414	280	661	8e-41	166
rs:WP_002576229	DNA topoisomerase III [[Clostridium] bolteae].	30.35	425	261	12	34	445	224	626	8e-41	164
rs:WP_022354483	DNA topoisomerase III [Bacteroides sp. CAG:875].	30.36	359	238	8	40	396	265	613	8e-41	165
rs:WP_012552651	MULTISPECIES: topoisomerase III [Bacillus cereus group].	28.31	438	277	15	35	454	247	665	8e-41	165
rs:WP_012806869	DNA topoisomerase III [Candidatus Accumulibacter phosphatis].	32.37	414	229	13	40	426	255	644	8e-41	166
rs:WP_001681355	DNA topoisomerase III, partial [Salmonella enterica].	39.70	199	118	2	36	234	251	447	8e-41	162
rs:WP_001235759	DNA topoisomerase III, partial [Escherichia coli].	33.33	267	173	2	37	302	245	507	8e-41	163
tr:A0A0E8NXL4_MYCTX	SubName: Full=DNA topoisomerase I (Omega-protein) {ECO:0000313|EMBL:CRF28766.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRF28766.1};	33.44	317	181	7	98	391	1	310	8e-41	162
rs:WP_008701761	DNA topoisomerase [Fusobacterium nucleatum].	31.46	356	229	7	37	382	233	583	8e-41	164
rs:WP_002879284	DNA topoisomerase [Lactobacillus delbrueckii].	31.31	412	248	13	57	454	269	659	8e-41	164
rs:WP_000542404	MULTISPECIES: topoisomerase III [Bacillus cereus group].	28.31	438	277	15	35	454	247	665	8e-41	164
rs:WP_035674877	DNA topoisomerase III, partial [Azospirillum brasilense].	33.53	337	197	10	67	385	258	585	8e-41	164
rs:WP_020505068	hypothetical protein [Lamprocystis purpurea].	29.90	408	266	4	59	451	256	658	8e-41	166
rs:WP_035165068	topoisomerase I [Lactobacillus delbrueckii].	31.31	412	248	13	57	454	269	659	8e-41	164
rs:WP_016223842	DNA topoisomerase III [Lachnospiraceae bacterium 3-2].	29.20	411	263	9	40	439	228	621	9e-41	164
rs:WP_022367814	DNA topoisomerase III [Firmicutes bacterium CAG:882].	30.66	411	257	12	3	392	246	649	9e-41	164
rs:WP_022451462	DNA topoisomerase [Clostridium sp. CAG:269].	30.47	384	232	11	47	398	270	650	9e-41	164
rs:WP_031892018	DNA topoisomerase III, partial [Staphylococcus aureus].	30.14	345	217	5	35	371	227	555	9e-41	163
rs:WP_042967269	DNA topoisomerase III [Escherichia coli].	26.99	415	276	6	37	432	247	653	9e-41	164
rs:WP_002590573	MULTISPECIES: DNA topoisomerase III [Lachnospiraceae].	31.90	420	253	13	37	445	227	624	9e-41	164
rs:WP_009322007	DNA topoisomerase III [Subdoligranulum sp. 4_3_54A2FAA].	30.56	432	260	14	34	450	224	630	9e-41	164
rs:WP_022296137	DNA topoisomerase III [Firmicutes bacterium CAG:272].	30.81	396	233	12	47	426	235	605	9e-41	164
rs:WP_009983779	DNA topoisomerase III [Ruminococcus flavefaciens].	30.43	414	248	13	37	443	227	607	9e-41	164
rs:WP_021434670	DNA topoisomerase III [Peptoclostridium difficile].	31.89	417	252	12	40	445	228	623	9e-41	164
rs:WP_008791950	DNA topoisomerase III [Coprobacillus sp. 8_2_54BFAA].	30.84	428	254	13	32	445	216	615	9e-41	164
rs:WP_036279667	DNA topoisomerase III [Methylocystis sp. ATCC 49242].	34.71	340	189	10	69	385	260	589	9e-41	164
rs:WP_022584315	DNA topoisomerase III [Brevibacillus laterosporus].	29.47	431	286	9	36	454	244	668	1e-40	165
rs:WP_008639302	MULTISPECIES: DNA topoisomerase III [Bacillaceae].	29.46	404	258	12	59	454	270	654	1e-40	164
rs:WP_000604073	hypothetical protein [Escherichia coli].	26.99	415	276	6	37	432	247	653	1e-40	164
rs:WP_033617346	topoisomerase I, partial [Lactobacillus plantarum].	32.87	356	206	10	29	369	36	373	1e-40	160
rs:WP_008978034	DNA topoisomerase III [Erysipelotrichaceae bacterium 5_2_54FAA].	31.78	428	256	14	31	445	220	624	1e-40	164
rs:WP_009003584	DNA topoisomerase III [Clostridium sp. D5].	32.06	418	251	13	39	445	229	624	1e-40	164
rs:WP_008982916	DNA topoisomerase III [Ruminococcaceae bacterium D16].	30.79	432	259	14	34	450	224	630	1e-40	164
rs:WP_002569178	MULTISPECIES: DNA topoisomerase III [Firmicutes].	31.78	428	256	14	31	445	220	624	1e-40	164
rs:WP_042253442	topoisomerase I [Lactobacillus brevis].	31.70	347	220	7	56	397	268	602	1e-40	164
rs:WP_022182875	DNA topoisomerase [Clostridium sp. CAG:575].	29.29	396	233	11	47	398	272	664	1e-40	164
tr:D4LTS8_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.65	398	242	12	61	445	249	625	1e-40	164
rs:WP_026969602	DNA topoisomerase III [Algoriphagus terrigena].	28.95	380	254	8	18	396	212	576	1e-40	165
rs:WP_014546643	DNA topoisomerase III [Fibrobacter succinogenes].	32.61	368	218	10	28	385	275	622	1e-40	165
rs:WP_033542386	DNA topoisomerase III [Planococcus sp. CAU13].	30.86	418	243	15	57	456	264	653	1e-40	164
rs:WP_003618392	DNA topoisomerase [Lactobacillus delbrueckii].	31.55	412	247	13	57	454	269	659	1e-40	164
rs:WP_044943098	DNA topoisomerase III [Blautia schinkii].	29.90	418	259	11	40	445	228	623	1e-40	164
rs:WP_036666677	DNA topoisomerase III, partial [Paenibacillus darwinianus].	31.20	375	229	9	40	391	234	602	1e-40	164
rs:WP_034219466	DNA topoisomerase, partial [Lachnospiraceae bacterium AC2014].	30.49	387	244	8	35	398	258	642	1e-40	164
rs:WP_022621591	DNA topoisomerase III; Tn1549-like, CTn4-Orf15 [Peptoclostridium difficile].	31.50	419	251	12	40	445	228	623	1e-40	164
tr:F4BPK6_CARS1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.24	410	254	11	58	454	267	657	1e-40	164
rs:WP_031271200	DNA topoisomerase III, partial [Lachnospiraceae bacterium 10-1].	31.34	402	245	11	37	425	126	509	1e-40	163
rs:WP_033678243	DNA topoisomerase I [Bacillus gaemokensis].	28.17	426	285	10	35	454	239	649	1e-40	166
rs:WP_041556619	DNA topoisomerase III [Carnobacterium sp. 17-4].	30.24	410	254	11	58	454	263	653	1e-40	164
rs:WP_016147228	DNA topoisomerase III [Butyricicoccus pullicaecorum].	30.22	417	257	11	40	445	228	621	1e-40	164
rs:WP_035357163	ATP-dependent DNA helicase RecQ [Edaphobacter aggregans].	32.64	383	239	9	26	398	252	625	1e-40	167
tr:R9MBF0_9FIRM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOS68163.1};	33.51	373	224	8	34	396	90	448	1e-40	163
rs:WP_044904480	DNA topoisomerase III, partial [Lachnospiraceae bacterium 3-2].	33.51	373	224	8	34	396	121	479	1e-40	163
rs:WP_000542403	topoisomerase III [Bacillus cereus].	27.98	436	281	14	35	454	247	665	1e-40	164
rs:WP_002577979	DNA topoisomerase III [[Clostridium] bolteae].	29.93	421	263	13	40	450	230	628	1e-40	164
rs:WP_040146911	DNA topoisomerase III, partial [Xanthomonas citri].	36.89	244	138	4	36	268	241	479	1e-40	162
rs:WP_004802669	DNA topoisomerase III [Eggerthia catenaformis].	29.79	423	247	11	40	445	228	617	1e-40	164
tr:R9N328_9FIRM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOS77715.1};	31.34	402	245	11	37	425	94	477	1e-40	163
rs:WP_040649807	DNA topoisomerase III [Ruminococcaceae bacterium D16].	30.66	424	260	11	32	445	216	615	1e-40	164
rs:WP_009906246	DNA topoisomerase III [Peptoclostridium difficile].	31.89	417	252	12	40	445	228	623	1e-40	164
rs:WP_006847775	DNA topoisomerase III [Prevotella copri].	29.58	409	245	11	24	398	217	616	1e-40	164
rs:WP_026831086	DNA topoisomerase III [Exiguobacterium antarcticum].	29.70	431	263	12	40	454	245	651	1e-40	164
rs:WP_014779928	DNA topoisomerase III [Thiocystis violascens].	30.71	420	250	10	59	446	256	666	1e-40	165
rs:WP_002596359	DNA topoisomerase III [[Clostridium] clostridioforme].	31.39	411	255	10	40	443	229	619	2e-40	164
rs:WP_009003369	DNA topoisomerase III [Clostridium sp. D5].	30.86	405	251	10	34	425	224	612	2e-40	164
rs:WP_021458968	DNA topoisomerase III [Staphylococcus sp. EGD-HP3].	29.39	347	220	5	54	391	246	576	2e-40	164
rs:WP_035651436	hypothetical protein, partial [Lachnospiraceae bacterium AD3010].	30.81	422	251	14	13	396	236	654	2e-40	163
tr:F4XGQ5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.66	424	260	11	32	445	257	656	2e-40	164
rs:WP_036166280	DNA topoisomerase III [Lysinibacillus sphaericus].	29.47	414	243	11	66	450	274	667	2e-40	164
rs:WP_029499016	DNA topoisomerase III [Kurthia huakuii].	30.83	412	244	12	58	452	268	655	2e-40	164
rs:WP_017649217	hypothetical protein [Streptococcus agalactiae].	30.21	384	234	11	86	455	298	661	2e-40	164
rs:WP_035236464	ATP-dependent DNA helicase RecQ, partial [Acidobacteriaceae bacterium URHE0068].	34.37	355	211	8	61	398	290	639	2e-40	165
rs:WP_016322370	DNA topoisomerase III [Oscillibacter sp. 1-3].	28.95	411	264	9	40	439	228	621	2e-40	164
rs:WP_023662392	DNA topoisomerase III, partial [Pseudomonas taiwanensis].	41.55	207	118	2	36	240	241	446	2e-40	161
tr:W7B1H7_9LIST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.73	371	207	12	102	449	2	345	2e-40	160
rs:WP_002584840	MULTISPECIES: DNA topoisomerase III [Lachnoclostridium].	33.51	373	224	8	34	396	222	580	2e-40	164
rs:WP_017766990	hypothetical protein, partial [Streptococcus agalactiae].	30.21	384	234	11	86	455	298	661	2e-40	164
rs:WP_026701296	hypothetical protein [Bacillus aidingensis].	28.61	409	267	10	59	453	267	664	2e-40	164
rs:WP_009766667	DNA topoisomerase III [Sporosarcina newyorkensis].	29.33	433	268	11	40	450	248	664	2e-40	164
rs:WP_036716163	DNA topoisomerase III, partial [Paenibacillus darwinianus].	31.20	375	229	9	40	391	234	602	2e-40	163
rs:WP_036579540	DNA topoisomerase III, partial [Paenibacillus darwinianus].	31.20	375	229	9	40	391	234	602	2e-40	163
rs:WP_038486162	DNA topoisomerase III, partial [Bacillus lehensis].	29.27	386	254	9	54	431	262	636	2e-40	164
rs:WP_022792534	DNA topoisomerase III [Marinococcus halotolerans].	29.10	409	264	12	59	454	266	661	2e-40	164
tr:A0A060M1P7_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.27	386	254	9	54	431	262	636	2e-40	164
rs:WP_014081130	DNA topoisomerase III [Roseburia hominis].	31.39	411	255	10	40	443	229	619	2e-40	163
rs:WP_044906257	DNA topoisomerase III [[Clostridium] innocuum].	32.41	398	223	14	60	445	247	610	2e-40	163
rs:WP_035408996	DNA topoisomerase III [Exiguobacterium sp. RIT341].	29.74	427	268	11	40	454	245	651	2e-40	163
rs:WP_007195525	DNA topoisomerase III [Thiocapsa marina].	30.64	359	229	7	59	402	264	617	2e-40	165
rs:WP_014343770	DNA topoisomerase III [Aliivibrio fischeri].	35.39	243	146	3	32	271	235	469	2e-40	162
rs:WP_003625660	DNA topoisomerase III [Lactobacillus helveticus].	32.86	350	212	9	56	397	268	602	2e-40	163
rs:WP_003342705	DNA topoisomerase III [Brevibacillus laterosporus].	29.47	431	286	10	36	454	244	668	2e-40	164
rs:WP_009662480	DNA topoisomerase III [Lachnoanaerobaculum sp. ICM7].	33.80	355	202	11	61	392	288	632	2e-40	163
tr:A0A0F6BYG0_ECOLX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AEB22157.1};	26.99	415	276	6	37	432	295	701	2e-40	164
rs:WP_014969939	DNA topoisomerase III [Exiguobacterium antarcticum].	29.69	421	258	11	40	446	245	641	2e-40	163
rs:WP_027955625	DNA topoisomerase III [Halobacillus kuroshimensis].	29.06	413	253	12	59	454	270	659	2e-40	163
rs:WP_039678617	DNA topoisomerase III [Terrisporobacter othiniensis].	29.92	371	216	7	65	428	266	599	2e-40	163
rs:WP_031921360	DNA topoisomerase III, partial [Staphylococcus aureus].	29.88	338	213	5	35	364	79	400	2e-40	160
rs:WP_015045035	DNA topoisomerase III [Dehalobacter sp. CF].	31.74	397	241	11	40	426	228	604	2e-40	163
rs:WP_046388544	DNA topoisomerase [Streptococcus uberis].	30.21	384	234	11	86	455	298	661	2e-40	163
rs:WP_017755419	hypothetical protein [Bacillus sp. ZYK].	29.48	424	265	12	37	450	249	648	2e-40	163
rs:WP_016381855	DNA topoisomerase III [Lactobacillus paracasei].	32.00	350	215	10	56	397	268	602	2e-40	163
rs:WP_028545467	DNA topoisomerase III [Paenibacillus taiwanensis].	31.36	405	226	14	27	391	222	614	2e-40	164
rs:WP_023510288	DNA topoisomerase III [Sporolactobacillus laevolacticus].	28.54	396	244	7	38	428	233	594	2e-40	163
rs:WP_009263227	DNA topoisomerase III [Lachnospiraceae bacterium 9_1_43BFAA].	31.37	408	250	11	31	425	218	608	2e-40	163
tr:A0A0B0HJQ3_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.99	294	167	4	36	328	231	495	2e-40	161
rs:WP_029471079	DNA topoisomerase III [Clostridiales bacterium VE202-06].	30.69	404	244	11	56	445	244	625	2e-40	163
rs:WP_016290959	DNA topoisomerase III [Lachnospiraceae bacterium 28-4].	31.34	402	245	11	37	425	227	610	2e-40	163
rs:WP_015495977	DNA recombination protein RmuC [Octadecabacter arcticus].	33.33	354	214	11	38	377	232	577	3e-40	163
rs:WP_007045892	DNA topoisomerase III [Subdoligranulum variabile].	31.58	399	237	12	57	439	243	621	3e-40	163
rs:WP_042060806	DNA topoisomerase III [Escherichia coli].	26.75	415	277	6	37	432	247	653	3e-40	163
rs:WP_008982747	DNA topoisomerase III [Ruminococcaceae bacterium D16].	32.60	362	227	7	39	396	229	577	3e-40	163
rs:WP_040212160	DNA topoisomerase [Clostridium sp. MS1].	31.22	426	245	17	48	452	262	660	3e-40	163
rs:WP_031419831	DNA topoisomerase III [Lysinibacillus sphaericus].	29.64	415	241	12	66	450	274	667	3e-40	163
rs:WP_027109670	DNA topoisomerase III [Lachnospiraceae bacterium NC2008].	29.53	430	244	15	3	392	245	655	3e-40	163
rs:WP_036161385	DNA topoisomerase III [Lysinibacillus sphaericus].	29.64	415	241	12	66	450	274	667	3e-40	163
rs:WP_009203366	DNA topoisomerase III [Anaerostipes hadrus].	31.70	347	219	11	69	401	297	639	3e-40	162
tr:C5QM86_9STAP	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.46	404	255	9	54	450	247	627	3e-40	163
rs:WP_005841655	DNA topoisomerase, partial [Bacteroides vulgatus].	32.32	396	242	11	35	427	62	434	3e-40	161
rs:WP_008707174	DNA topoisomerase III [Rhodopirellula maiorica].	33.72	347	218	7	60	404	260	596	3e-40	164
rs:WP_037541589	MULTISPECIES: DNA topoisomerase III [Staphylococcus].	29.46	404	255	9	54	450	246	626	3e-40	163
rs:WP_012294074	DNA topoisomerase III [Lysinibacillus sphaericus].	29.64	415	241	12	66	450	274	667	3e-40	163
rs:WP_044930836	DNA topoisomerase III [Clostridium sp. M62/1].	31.38	427	246	15	40	450	228	623	3e-40	162
rs:WP_026706744	DNA topoisomerase III [Flavobacterium frigidarium].	30.96	365	237	8	38	401	231	581	3e-40	163
rs:WP_015254593	DNA topoisomerase III [Thermobacillus composti].	30.53	380	235	10	34	391	228	600	3e-40	163
rs:WP_002509280	DNA topoisomerase III [Staphylococcus arlettae].	29.39	347	220	5	54	391	246	576	3e-40	163
rs:WP_029437123	DNA topoisomerase I [Bacillus thuringiensis].	28.54	431	283	9	32	454	236	649	3e-40	164
rs:WP_016110475	DNA topoisomerase III [Bacillus cereus].	28.31	431	284	9	32	454	236	649	3e-40	164
tr:D4CB69_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.38	427	246	15	40	450	245	640	3e-40	162
rs:WP_029092222	hypothetical protein [Brochothrix thermosphacta].	32.11	380	231	11	57	428	266	626	4e-40	162
rs:WP_022126066	DNA topoisomerase III [Bacteroides coprocola CAG:162].	29.83	362	242	8	37	396	230	581	4e-40	162
rs:WP_035020436	DNA topoisomerase III [Carnobacterium sp. WN1374].	30.00	410	255	11	58	454	263	653	4e-40	162
rs:WP_007591669	DNA topoisomerase III [Lachnoanaerobaculum sp. OBRC5-5].	31.94	360	220	9	51	392	280	632	4e-40	162
rs:WP_035184697	topoisomerase I [Lactobacillus delbrueckii].	31.07	412	249	13	57	454	269	659	4e-40	162
rs:WP_045524421	DNA topoisomerase III [Bacillus niacini].	28.11	402	254	7	36	434	230	599	4e-40	162
rs:WP_027625981	DNA topoisomerase III [Clostridium lundense].	29.00	469	280	16	31	454	262	722	4e-40	163
rs:WP_034212370	DNA topoisomerase III [Lachnoanaerobaculum sp. MSX33].	32.23	363	215	10	51	392	280	632	4e-40	162
rs:WP_022146082	DNA topoisomerase [Firmicutes bacterium CAG:238].	28.78	410	249	9	59	443	264	655	4e-40	164
rs:WP_005933789	DNA topoisomerase III [Faecalibacterium prausnitzii].	31.22	426	243	12	40	445	96	491	4e-40	162
rs:WP_004063538	DNA topoisomerase III [Eubacterium plexicaudatum].	31.86	361	220	9	78	425	266	613	4e-40	162
rs:WP_003510888	DNA topoisomerase III [[Clostridium] symbiosum].	32.04	387	239	10	47	425	235	605	4e-40	162
tr:G8AN84_AZOBR	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	32.84	341	200	10	67	385	261	594	4e-40	163
rs:WP_023383812	DNA topoisomerase [Pseudomonas sp. VLB120].	30.94	404	246	11	22	402	235	628	4e-40	164
rs:WP_022617840	DNA topoisomerase III; Tn1549-like, CTn4-Orf15 [Peptoclostridium difficile].	31.74	419	250	13	40	445	228	623	4e-40	162
rs:WP_000214250	hypothetical protein [Streptococcus agalactiae].	30.26	380	231	11	90	455	302	661	4e-40	162
rs:WP_041811868	DNA topoisomerase III [Azospirillum brasilense].	32.84	341	200	10	67	385	258	591	4e-40	163
rs:WP_004574786	DNA topoisomerase [Pseudomonas putida].	31.66	398	240	11	28	402	240	628	4e-40	164
rs:WP_003660153	DNA topoisomerase III [Lactobacillus paracasei].	31.81	349	217	8	56	397	268	602	4e-40	162
rs:WP_007886640	DNA topoisomerase III [Roseburia inulinivorans].	30.32	432	261	14	34	450	224	630	4e-40	162
rs:WP_018112824	DNA topoisomerase III [Peptoclostridium difficile].	31.06	425	245	10	40	445	228	623	4e-40	162
rs:WP_035408325	DNA topoisomerase III [Bacillus sp. SJS].	31.16	398	242	13	67	453	275	651	4e-40	162
rs:WP_029731804	DNA topoisomerase III [Dorea sp. AGR2135].	30.60	402	237	13	61	445	249	625	4e-40	162
rs:WP_029054036	DNA topoisomerase III [Sporosarcina ureae].	29.77	430	265	13	46	456	251	662	5e-40	162
rs:WP_020736077	ATP-dependent DNA helicase RecQ [Sorangium cellulosum].	32.64	383	211	9	61	402	294	670	5e-40	165
rs:WP_040313084	DNA topoisomerase III [Bacteroides plebeius].	30.36	359	238	8	40	396	265	613	5e-40	162
rs:WP_027158454	DNA topoisomerase [Methylobacter luteus].	32.28	378	238	9	26	398	220	584	5e-40	163
rs:WP_014386915	DNA topoisomerase [Pediococcus claussenii].	31.12	347	220	8	57	397	269	602	5e-40	162
rs:WP_002573997	DNA topoisomerase III [[Clostridium] bolteae].	31.40	363	236	7	40	398	230	583	5e-40	162
rs:WP_019875135	DNA topoisomerase [Lactobacillus paracasei].	31.52	349	220	9	57	399	269	604	5e-40	162
rs:WP_004797795	DNA topoisomerase III [[Eubacterium] dolichum].	30.32	432	261	14	34	450	224	630	5e-40	162
rs:WP_022053972	DNA topoisomerase III [Bacteroides plebeius CAG:211].	30.36	359	238	8	40	396	265	613	5e-40	162
rs:WP_044466810	DNA topoisomerase III [Staphylococcus caprae].	29.21	404	256	9	54	450	246	626	5e-40	162
rs:WP_018395842	hypothetical protein [Bacillus sp. 37MA].	29.95	414	260	12	55	456	264	659	5e-40	162
rs:WP_046041317	topoisomerase I [Lactobacillus plantarum].	32.30	356	206	10	56	397	268	602	5e-40	162
tr:D6DF30_CLOSC	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	32.00	400	233	13	57	439	243	620	6e-40	162
rs:WP_027996519	DNA topoisomerase III [Simplicispira psychrophila].	32.43	370	225	10	47	399	270	631	6e-40	164
rs:WP_008979388	DNA topoisomerase III [Erysipelotrichaceae bacterium 5_2_54FAA].	27.84	431	277	11	35	450	241	652	6e-40	162
rs:WP_009447128	DNA topoisomerase III [Lachnospiraceae bacterium oral taxon 082].	31.98	394	247	9	40	425	230	610	6e-40	162
rs:WP_015007093	MULTISPECIES: DNA topoisomerase [Lactobacillales].	28.96	442	262	15	33	446	241	658	6e-40	162
rs:WP_011861108	DNA topoisomerase III [Peptoclostridium difficile].	31.50	419	251	13	40	445	228	623	6e-40	162
rs:WP_035425603	DNA topoisomerase III [Bacillus ligniniphilus].	28.21	429	268	11	38	446	246	654	6e-40	162
tr:A0A061NAW1_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.63	411	245	12	59	456	253	640	6e-40	162
tr:G0LYH7_LACPE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.01	353	211	9	56	397	268	602	6e-40	162
rs:WP_003590797	DNA topoisomerase III [Lactobacillus casei].	32.09	349	214	10	57	397	269	602	6e-40	162
rs:WP_021866241	DNA topoisomerase [Eubacterium sp. CAG:86].	30.83	399	246	13	22	393	245	640	6e-40	162
rs:WP_008687136	DNA topoisomerase III [Eubacterium sp. 3_1_31].	29.59	392	242	11	74	450	280	652	7e-40	162
rs:WP_000520756	DNA topoisomerase I [Bacillus cereus].	27.70	426	287	10	35	454	239	649	7e-40	163
rs:WP_011875776	DNA topoisomerase [Burkholderia vietnamiensis].	34.91	381	186	14	40	387	263	614	7e-40	163
rs:WP_021661456	DNA topoisomerase [Clostridium sp. ATCC 29733].	31.16	414	250	11	47	440	235	633	7e-40	162
tr:U6FEN0_LACHE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.73	353	212	9	56	397	60	394	7e-40	160
tr:F6IZ93_LACPE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.11	380	225	12	33	397	68	429	7e-40	160
rs:WP_036142091	DNA topoisomerase III [Lysinibacillus sp. BF-4].	29.15	446	258	16	29	454	246	653	7e-40	162
rs:WP_035711184	hypothetical protein, partial [Bacillus aidingensis].	28.47	439	283	10	30	453	225	647	7e-40	162
tr:S2SI22_LACPA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.70	347	218	9	57	397	269	602	8e-40	162
rs:WP_044278347	DNA topoisomerase III, partial [Campylobacter jejuni].	33.33	285	184	4	32	313	233	514	8e-40	160
rs:WP_024226552	hypothetical protein, partial [Escherichia coli].	32.85	274	171	3	123	387	1	270	8e-40	155
rs:WP_025436673	DNA topoisomerase [Eubacterium acidaminophilum].	32.31	390	223	11	30	398	264	633	8e-40	161
rs:WP_037545408	DNA topoisomerase III [Staphylococcus lugdunensis].	28.20	422	275	9	35	450	227	626	8e-40	162
rs:WP_003561259	DNA topoisomerase III [Lactobacillus buchneri].	31.53	352	212	8	57	397	269	602	8e-40	162
rs:WP_018671825	DNA topoisomerase III [Brevibacillus laterosporus].	29.20	435	282	10	36	454	244	668	8e-40	162
rs:WP_005922872	DNA topoisomerase III [Faecalibacterium prausnitzii].	31.49	362	231	8	39	396	229	577	9e-40	161
tr:B5D0F1_BACPM	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EDY94995.1};	30.36	359	238	8	40	396	296	644	9e-40	162
rs:WP_027365920	DNA topoisomerase III, partial [Desulfotomaculum alcoholivorax].	34.67	274	174	3	38	310	237	506	9e-40	160
rs:WP_021361815	DNA topoisomerase III [Peptoclostridium difficile].	31.50	419	251	13	40	445	228	623	9e-40	161
rs:WP_021422174	DNA topoisomerase III [Peptoclostridium difficile].	31.22	426	243	12	40	445	228	623	9e-40	161
rs:WP_002322390	DNA topoisomerase, partial [Enterococcus faecium].	32.13	389	238	9	52	427	162	537	9e-40	160
rs:WP_024717739	MULTISPECIES: DNA topoisomerase [Pseudomonas].	31.17	401	238	11	29	402	239	628	9e-40	163
rs:WP_036081149	DNA topoisomerase III [Lysinibacillus boronitolerans].	31.77	406	248	12	59	454	269	655	9e-40	161
rs:WP_014642662	DNA topoisomerase III [Halobacillus halophilus].	28.75	407	260	12	59	454	270	657	9e-40	161
rs:WP_031358079	DNA topoisomerase III, partial [Burkholderia sordidicola].	33.70	359	215	9	40	385	237	585	9e-40	161
rs:WP_004081256	DNA topoisomerase III [Clostridium sp. ASF502].	31.33	415	256	12	40	445	230	624	9e-40	161
tr:A0A098EIM9_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.56	406	256	13	59	454	266	651	9e-40	161
rs:WP_002322285	DNA topoisomerase, partial [Enterococcus faecium].	32.13	389	238	9	52	427	161	536	9e-40	160
tr:F6IUN4_LACPE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.43	350	221	9	56	399	269	605	1e-39	161
rs:WP_040175367	hypothetical protein, partial [Phaeobacter sp. S26].	31.44	369	229	8	40	392	236	596	1e-39	161
rs:WP_043567723	DNA topoisomerase III [Candidatus Accumulibacter sp. BA-93].	31.44	423	238	13	40	435	255	652	1e-39	163
tr:G9QDN0_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.46	426	288	10	35	454	110	520	1e-39	162
rs:WP_000520741	DNA topoisomerase I [Bacillus cereus].	27.70	426	287	10	35	454	239	649	1e-39	163
rs:WP_028229620	DNA topoisomerase [Burkholderia ferrariae].	30.32	409	246	8	40	428	260	649	1e-39	162
rs:WP_000520744	DNA topoisomerase I [Bacillus cereus].	27.70	426	287	10	35	454	239	649	1e-39	163
rs:WP_022110771	DNA topoisomerase III [Prevotella sp. CAG:604].	29.62	395	240	9	24	385	217	606	1e-39	161
rs:WP_012552822	DNA topoisomerase III [Lactobacillus casei].	31.65	357	207	9	56	397	268	602	1e-39	161
rs:WP_043902450	DNA topoisomerase, partial [Enterococcus faecium].	31.70	407	244	11	52	444	264	650	1e-39	161
rs:WP_013721070	DNA topoisomerase III [Lactobacillus buchneri].	30.62	356	212	8	56	397	268	602	1e-39	161
rs:WP_025147939	DNA topoisomerase I [Bacillus sp. H1a].	27.46	426	288	10	35	454	239	649	1e-39	163
rs:WP_008344184	DNA topoisomerase [Burkholderia sp. SJ98].	31.48	413	236	11	40	428	260	649	1e-39	162
rs:WP_028585602	DNA topoisomerase III [Desulfobulbus mediterraneus].	30.40	375	236	8	38	402	258	617	1e-39	162
rs:WP_034918008	DNA topoisomerase III, partial [Candidatus Accumulibacter sp. BA-91].	31.37	424	237	15	40	435	94	491	1e-39	161
rs:WP_021876076	DNA topoisomerase [Clostridium chauvoei].	31.25	416	243	13	3	403	249	636	1e-39	160
rs:WP_002588924	MULTISPECIES: DNA topoisomerase III [Clostridiales].	30.65	385	243	8	23	396	211	582	1e-39	161
rs:WP_014078553	DNA topoisomerase III [Roseburia hominis].	30.23	430	264	13	34	450	224	630	1e-39	161
rs:WP_003526250	hypothetical protein, partial [[Clostridium] clostridioforme].	30.50	400	240	12	60	445	2	377	1e-39	159
tr:B3DUF7_METI4	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.81	371	218	10	61	415	274	625	1e-39	162
rs:WP_009058926	topoisomerase I [Methylacidiphilum fumariolicum].	32.12	411	246	15	22	417	238	630	1e-39	162
rs:WP_002351810	DNA topoisomerase III, partial [Enterococcus faecium].	32.13	389	238	9	52	427	264	639	1e-39	160
rs:WP_016128043	DNA topoisomerase III [Bacillus cereus].	27.70	426	287	10	35	454	239	649	1e-39	162
tr:A0A080LRY5_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.37	424	237	15	40	435	78	475	1e-39	161
rs:WP_024855755	DNA topoisomerase III [Lactobacillus brevis].	32.11	380	225	12	33	397	241	602	1e-39	161
rs:WP_032825010	topoisomerase I, partial [Oenococcus oeni].	31.44	353	213	9	56	397	60	394	1e-39	158
rs:WP_021994635	DNA topoisomerase [Burkholderia sp. K4410.MGS-135].	32.52	409	222	14	40	425	256	633	1e-39	162
rs:WP_007566776	DNA topoisomerase III [Bacteroides coprocola].	30.11	362	241	8	37	396	230	581	1e-39	161
tr:W4RZL4_9XANT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE49104.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAE49104.1};	35.52	259	157	4	197	454	7	256	1e-39	154
tr:R8CKW2_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.46	426	288	10	35	454	239	649	1e-39	162
rs:WP_034319070	DNA topoisomerase III, partial [Helicobacter trogontum].	29.55	335	221	5	66	385	268	602	1e-39	160
rs:WP_018783115	DNA topoisomerase I [Bacillus sp. 95MFCvi2.1].	28.31	431	284	9	32	454	236	649	1e-39	162
rs:WP_016486988	MULTISPECIES: hypothetical protein [Pseudomonas putida group].	31.84	380	224	10	29	384	239	607	1e-39	162
rs:WP_047421924	DNA topoisomerase I, partial [Bacillus anthracis].	27.12	424	292	9	35	454	239	649	1e-39	162
rs:WP_037543463	DNA topoisomerase III [Staphylococcus lugdunensis].	28.20	422	275	9	35	450	227	626	1e-39	161
rs:WP_044920444	hypothetical protein [Anaerostipes hadrus].	28.97	428	276	11	36	450	230	642	1e-39	161
rs:WP_033399204	hypothetical protein, partial [Desulfospira joergensenii].	30.44	427	260	13	35	450	226	626	1e-39	161
rs:WP_044907008	DNA topoisomerase III [[Clostridium] innocuum].	28.14	430	277	11	35	450	241	652	1e-39	161
rs:WP_043308972	hypothetical protein, partial [Bacillus sp. 7_6_55CFAA_CT2].	27.46	426	288	10	35	454	127	537	1e-39	161
rs:WP_010752776	DNA topoisomerase III [Enterococcus asini].	28.99	407	248	9	40	445	235	601	1e-39	160
rs:WP_009270778	DNA topoisomerase III [Erysipelotrichaceae bacterium 21_3].	35.28	343	194	10	67	396	257	584	1e-39	161
rs:WP_021801651	DNA topoisomerase III [Clostridium intestinale].	33.33	381	225	14	35	399	259	626	2e-39	160
rs:WP_007061961	DNA topoisomerase III [Clostridium carboxidivorans].	31.28	358	223	9	57	399	292	641	2e-39	161
tr:R8UL10_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.78	419	295	7	40	450	102	512	2e-39	160
rs:WP_022341006	DNA topoisomerase III [Roseburia sp. CAG:309].	32.87	356	208	11	72	399	306	658	2e-39	160
rs:WP_042866226	DNA topoisomerase III [Bacillus cereus].	25.78	419	295	7	40	450	133	543	2e-39	160
tr:D4RDK3_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.01	387	241	10	54	424	58	434	2e-39	159
tr:G5GJE6_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.25	384	236	10	40	414	242	606	2e-39	161
rs:WP_040882743	DNA topoisomerase III [Johnsonella ignava].	31.25	384	236	10	40	414	226	590	2e-39	160
tr:E6MAJ7_STALU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.20	422	275	9	35	450	232	631	2e-39	161
rs:WP_047674912	topoisomerase I [Lactobacillus plantarum].	31.71	350	216	10	56	397	268	602	2e-39	160
rs:WP_002094784	DNA topoisomerase I [Bacillus cereus].	27.46	426	288	10	35	454	239	649	2e-39	161
rs:WP_039721732	topoisomerase I [Methylacidiphilum kamchatkense].	31.39	411	249	14	22	417	238	630	2e-39	162
rs:WP_016998796	hypothetical protein [Staphylococcus lentus].	29.79	423	256	12	40	450	234	627	2e-39	160
rs:WP_034347888	DNA topoisomerase III, partial [Helicobacter trogontum].	29.55	335	221	5	66	385	268	602	2e-39	160
rs:WP_009511995	DNA topoisomerase III [Opitutaceae bacterium TAV5].	32.10	377	226	13	30	385	248	615	2e-39	162
rs:WP_041142936	topoisomerase I [Lactobacillus plantarum].	31.56	377	231	12	33	397	241	602	2e-39	160
rs:WP_023662223	DNA topoisomerase [Pseudomonas taiwanensis].	30.92	401	239	11	29	402	239	628	2e-39	162
rs:WP_032542096	DNA topoisomerase III, partial [Peptoclostridium difficile].	30.09	432	262	14	34	450	199	605	2e-39	160
rs:WP_010014514	DNA topoisomerase III [Lactobacillus coryniformis].	31.81	349	215	10	57	397	269	602	2e-39	160
tr:E8LH21_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.75	426	257	12	32	445	218	617	2e-39	160
rs:WP_036745280	hypothetical protein, partial [Peptoclostridium difficile].	30.96	407	252	11	31	426	237	625	2e-39	160
rs:WP_038704916	DNA topoisomerase III [Planococcus sp. PAMC 21323].	29.73	407	254	12	59	454	266	651	2e-39	160
rs:WP_036805062	DNA topoisomerase III [Planomicrobium glaciei].	29.98	407	253	15	59	454	266	651	2e-39	160
rs:WP_047956592	DNA topoisomerase III [Bacillus anthracis].	25.78	419	295	7	40	450	263	673	2e-39	162
rs:WP_046535048	DNA topoisomerase III [Candidatus Accumulibacter phosphatis].	31.14	395	227	10	65	435	279	652	2e-39	162
rs:WP_009257933	DNA topoisomerase III [Lachnospiraceae bacterium 7_1_58FAA].	32.11	383	217	13	78	445	261	615	2e-39	160
rs:WP_033389182	topoisomerase I, partial [Lactobacillus parabrevis].	30.67	375	237	10	33	397	72	433	2e-39	159
rs:WP_021397960	DNA topoisomerase III family protein [Peptoclostridium difficile].	30.75	426	257	12	32	445	216	615	2e-39	160
tr:A7AZM6_RUMGN	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.12	425	258	13	40	450	233	632	2e-39	160
rs:WP_042824672	DNA topoisomerase III, partial [Xanthomonas axonopodis].	37.50	224	134	2	167	387	6	226	2e-39	152
rs:WP_043588193	DNA topoisomerase [Diplosphaera colitermitum].	29.53	447	264	11	39	454	242	668	2e-39	161
rs:WP_036910457	DNA topoisomerase III, partial [Prevotella sp. FD3004].	29.34	392	258	10	18	396	212	597	2e-39	160
rs:WP_033121926	DNA topoisomerase III [Oscillibacter sp. ER4].	30.96	394	235	10	47	426	235	605	2e-39	160
rs:WP_039959342	DNA topoisomerase III [[Ruminococcus] gnavus].	30.12	425	258	13	40	450	231	630	2e-39	160
rs:WP_026508071	DNA topoisomerase III [Butyrivibrio sp. MC2013].	30.88	421	261	10	33	444	221	620	2e-39	160
rs:WP_022433308	DNA topoisomerase [Eubacterium sp. CAG:38].	32.70	370	229	12	41	392	261	628	2e-39	160
rs:WP_038136279	DNA topoisomerase III [Verrucomicrobia bacterium SCGC AAA168-F10].	30.91	372	229	9	40	399	264	619	2e-39	162
rs:WP_020151346	hypothetical protein [Verrucomicrobia bacterium SCGC AAA164-M04].	30.91	372	229	9	40	399	264	619	2e-39	162
rs:WP_021419783	DNA topoisomerase III [Peptoclostridium difficile].	32.69	364	228	9	40	396	228	581	2e-39	160
rs:WP_002578949	MULTISPECIES: DNA topoisomerase III [Firmicutes].	30.75	426	257	12	32	445	216	615	2e-39	160
rs:WP_016289142	DNA topoisomerase III [Lachnospiraceae bacterium 3-1].	30.62	405	243	12	56	445	244	625	2e-39	160
rs:WP_047401464	DNA topoisomerase I, partial [Bacillus anthracis].	27.12	424	292	9	35	454	239	649	3e-39	162
rs:WP_022583212	DNA topoisomerase III family protein [Peptoclostridium difficile].	30.09	432	262	14	34	450	224	630	3e-39	160
rs:WP_012236045	ATP-dependent DNA helicase RecQ [Sorangium cellulosum].	30.77	377	222	6	61	400	315	689	3e-39	163
rs:WP_044923851	DNA topoisomerase III [Anaerostipes hadrus].	31.41	347	220	11	69	401	297	639	3e-39	160
rs:WP_007139586	DNA topoisomerase [Flavobacterium frigoris].	31.95	338	217	6	59	393	259	586	3e-39	160
rs:WP_014565111	DNA topoisomerase [Lactobacillus delbrueckii].	31.07	412	249	13	57	454	269	659	3e-39	160
tr:A0A084ITG9_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.46	426	288	10	35	454	239	649	3e-39	162
tr:A0A0D6S764_BACMY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.46	426	288	10	35	454	1	411	3e-39	160
rs:WP_012423151	DNA topoisomerase [Clostridium botulinum].	30.04	446	266	15	26	452	236	654	3e-39	160
gp:AE011190_192	DNA topoisomerase [Bacillus anthracis str. A2012]	27.12	424	292	9	35	454	246	656	3e-39	162
rs:WP_039098910	topoisomerase I [Lactobacillus curvatus].	31.71	350	216	10	56	397	268	602	3e-39	160
rs:WP_003524694	hypothetical protein, partial [[Clostridium] clostridioforme].	30.62	405	242	13	60	450	3	382	3e-39	158
tr:A0A0D6ZHR8_LACDE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.07	412	249	13	57	454	269	659	3e-39	160
rs:WP_022375467	DNA topoisomerase [Firmicutes bacterium CAG:270].	28.68	408	250	7	26	428	224	595	3e-39	160
rs:WP_003508269	DNA topoisomerase [[Clostridium] symbiosum].	30.73	397	251	7	40	428	228	608	3e-39	160
rs:WP_006224636	DNA topoisomerase [Achromobacter piechaudii].	32.54	378	228	10	36	396	247	614	3e-39	161
rs:WP_015474661	DNA topoisomerase III [Lactobacillus brevis].	31.01	387	228	11	29	397	237	602	3e-39	160
rs:WP_003332668	DNA topoisomerase [Bacillus azotoformans].	30.68	427	258	15	36	450	249	649	3e-39	160
rs:WP_020157765	DNA topoisomerase [Methylobacter marinus].	31.21	423	255	14	39	453	233	627	3e-39	160
rs:WP_004070246	DNA topoisomerase III [Clostridium sp. ASF502].	33.69	374	222	10	34	396	222	580	3e-39	160
rs:WP_013274289	DNA topoisomerase III [[Clostridium] saccharolyticum].	30.85	402	240	13	40	426	228	606	3e-39	160
rs:WP_028913321	DNA topoisomerase III [Prevotella sp. MA2016].	29.29	396	246	10	18	385	212	601	3e-39	160
sp:TOP1_BACAN	RecName: Full=DNA topoisomerase 1; EC=5.99.1.2; AltName: Full=DNA topoisomerase I; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	27.12	424	292	9	35	454	222	632	3e-39	161
rs:WP_002193616	DNA topoisomerase I [Bacillus cereus].	27.70	426	287	10	35	454	239	649	3e-39	161
rs:WP_008391044	DNA topoisomerase III [Clostridium sp. SS2/1].	31.41	347	220	11	69	401	297	639	3e-39	159
rs:WP_016396426	DNA topoisomerase III family protein [Lactobacillus delbrueckii].	30.83	412	250	13	57	454	269	659	3e-39	160
rs:WP_009606218	DNA topoisomerase [Turicibacter sp. HGF1].	27.80	428	274	10	36	449	235	641	3e-39	161
tr:A0A0E0W8Z3_BACAN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.12	424	292	9	35	454	250	660	3e-39	161
rs:WP_000520727	DNA topoisomerase I [Bacillus anthracis].	27.12	424	292	9	35	454	239	649	3e-39	161
rs:WP_022312971	DNA topoisomerase [Clostridium sp. CAG:91].	28.71	418	250	13	3	392	254	651	3e-39	160
rs:WP_036949281	DNA topoisomerase, partial [Pseudobutyrivibrio ruminis].	29.20	435	264	13	47	446	272	697	3e-39	160
tr:J2Z439_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.70	347	218	7	57	397	89	422	3e-39	159
rs:WP_034132827	DNA topoisomerase [Peptococcaceae bacterium BICA1-8].	31.36	389	244	12	30	406	263	640	3e-39	159
rs:WP_003431259	DNA topoisomerase [Peptoclostridium difficile].	32.13	361	224	6	35	385	217	566	3e-39	160
rs:WP_022463020	DNA topoisomerase III [Blautia sp. CAG:37].	31.46	356	209	13	65	392	290	638	3e-39	160
rs:WP_044444178	DNA topoisomerase I, partial [Bacillus mycoides].	27.46	426	288	10	35	454	20	430	3e-39	159
rs:WP_033604912	MULTISPECIES: DNA topoisomerase, partial [Enterococcus].	31.73	353	208	10	114	452	1	334	3e-39	155
rs:WP_035457587	topoisomerase I, partial [Lactobacillus coryniformis].	31.70	347	218	7	57	397	81	414	3e-39	159
rs:WP_047796571	DNA topoisomerase III [Staphylococcus capitis].	28.64	426	268	11	35	450	227	626	3e-39	160
tr:A0A081BJM0_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.94	382	227	12	33	399	243	606	3e-39	160
rs:WP_002450320	DNA topoisomerase III [Staphylococcus warneri].	28.67	415	272	9	40	450	233	627	4e-39	160
rs:WP_008728394	DNA topoisomerase III [Erysipelotrichaceae bacterium 2_2_44A].	30.32	432	261	14	34	450	224	630	4e-39	160
rs:WP_016102507	DNA topoisomerase III [Bacillus cereus].	27.46	426	288	10	35	454	239	649	4e-39	161
rs:WP_034528476	topoisomerase I [Lactobacillus oryzae].	31.94	382	227	12	33	399	241	604	4e-39	160
rs:WP_002432733	DNA topoisomerase III [Staphylococcus capitis].	28.64	426	268	11	35	450	227	626	4e-39	160
rs:WP_041084686	DNA topoisomerase [Clostridium botulinum].	29.82	446	267	15	26	452	236	654	4e-39	160
rs:WP_034431315	ATP-dependent DNA helicase RecQ, partial [Candidatus Contendobacter odensis].	30.71	381	236	7	43	399	278	654	4e-39	162
rs:WP_013657846	DNA topoisomerase [Cellulosilyticum lentocellum].	28.22	450	281	16	29	452	248	681	4e-39	160
rs:WP_017825599	DNA topoisomerase [Clostridium botulinum].	29.82	446	267	15	26	452	236	654	4e-39	160
rs:WP_045040343	DNA topoisomerase III, partial [Photobacterium iliopiscarium].	39.71	204	122	1	182	385	6	208	4e-39	152
rs:WP_006783219	DNA topoisomerase [Turicibacter sanguinis].	27.80	428	274	10	36	449	235	641	4e-39	160
rs:WP_012450313	DNA topoisomerase [Clostridium botulinum].	29.82	446	267	15	26	452	236	654	4e-39	160
tr:W6LQR6_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.71	381	236	7	43	399	280	656	4e-39	162
rs:WP_029657060	DNA topoisomerase, partial [Enterococcus faecalis].	33.52	349	210	8	52	392	40	374	4e-39	156
rs:WP_048488314	topoisomerase I [Lactobacillus rhamnosus].	31.48	378	230	10	33	397	241	602	4e-39	159
rs:WP_021970827	DNA topoisomerase [Bacteroides sp. CAG:1076].	30.11	362	241	8	37	396	39	390	4e-39	158
tr:A0A091BZB1_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.54	403	249	8	43	445	203	566	4e-39	159
rs:WP_032825761	topoisomerase I, partial [Oenococcus oeni].	31.34	351	216	9	56	397	1	335	4e-39	157
rs:WP_012263710	DNA topoisomerase [Bacillus thuringiensis].	27.87	427	285	11	35	454	239	649	4e-39	161
rs:WP_008790355	MULTISPECIES: hypothetical protein [Coprobacillus].	30.14	418	230	14	74	459	280	667	4e-39	159
rs:WP_002585092	DNA topoisomerase III [[Clostridium] clostridioforme].	30.86	418	254	13	40	445	230	624	4e-39	159
rs:WP_007124650	DNA topoisomerase, partial [Lactobacillus antri].	31.53	352	212	9	57	397	227	560	4e-39	159
rs:WP_021985184	DNA topoisomerase [Clostridium sp. CAG:127].	30.87	392	235	13	36	404	270	648	4e-39	159
rs:WP_004560603	DNA topoisomerase [Lactobacillus delbrueckii].	31.07	412	249	13	57	454	269	659	5e-39	159
rs:WP_047674874	topoisomerase I [Lactobacillus plantarum].	31.41	347	219	9	57	397	269	602	5e-39	159
rs:WP_047441327	DNA topoisomerase I [Bacillus anthracis].	27.12	424	292	9	35	454	239	649	5e-39	161
rs:WP_000520740	DNA topoisomerase I [Bacillus cereus].	27.46	426	288	10	35	454	239	649	5e-39	161
rs:WP_032820832	topoisomerase I, partial [Oenococcus oeni].	31.34	351	216	9	56	397	1	335	5e-39	157
rs:WP_041877706	DNA topoisomerase III, partial [Verrucomicrobia bacterium SCGC AAA164-O14].	31.37	357	217	9	55	399	15	355	5e-39	159
rs:WP_035586006	hypothetical protein, partial [Eggerthella lenta].	32.12	411	243	12	59	445	247	645	5e-39	159
rs:WP_000520755	DNA topoisomerase I [Bacillus thuringiensis].	27.46	426	288	10	35	454	239	649	5e-39	161
rs:WP_022091491	DNA topoisomerase [Lachnospiraceae bacterium CAG:25].	28.96	404	254	6	26	428	224	595	5e-39	159
rs:WP_009264837	DNA topoisomerase III [Lachnospiraceae bacterium 5_1_63FAA].	32.09	349	215	12	69	401	297	639	5e-39	159
rs:WP_004066586	DNA topoisomerase III [Eubacterium plexicaudatum].	29.43	435	237	14	3	397	245	649	5e-39	159
rs:WP_006861796	DNA topoisomerase III [Marvinbryantia formatexigens].	33.62	351	211	12	67	400	294	639	5e-39	159
rs:WP_022091462	DNA topoisomerase III [Lachnospiraceae bacterium CAG:25].	32.09	349	215	12	69	401	297	639	5e-39	159
rs:WP_016105662	DNA topoisomerase III [Bacillus cereus].	27.40	427	287	10	35	454	239	649	5e-39	161
rs:WP_044923880	DNA topoisomerase III [Anaerostipes hadrus].	28.96	404	254	7	26	428	224	595	5e-39	159
tr:H3RLD1_PANSE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EHT97815.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EHT97815.1};	31.77	362	233	6	33	385	163	519	5e-39	158
tr:J9W7D3_LACBU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.32	380	228	11	33	397	33	394	5e-39	158
tr:X0RBQ7_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.45	372	228	10	35	404	238	584	5e-39	159
tr:D4LSE8_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.43	385	229	14	47	400	271	651	5e-39	159
rs:WP_020191335	hypothetical protein [Pseudomonas putida].	31.59	421	237	14	28	411	240	646	5e-39	160
rs:WP_045487459	DNA topoisomerase III [Bacillus sp. TS-2].	31.45	372	228	10	35	404	237	583	5e-39	159
rs:WP_035393366	MULTISPECIES: DNA topoisomerase III [Clostridiales].	31.74	397	243	11	40	426	228	606	5e-39	159
tr:C7H2S2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.74	397	243	11	40	426	245	623	5e-39	159
tr:K1V4F0_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC78771.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EKC78771.1};	30.08	399	245	13	62	445	246	625	5e-39	159
rs:WP_008617926	DNA topoisomerase I [Paraprevotella clara].	31.62	370	227	10	60	427	264	609	5e-39	159
rs:WP_044822506	DNA topoisomerase III [Bacillus thuringiensis].	25.78	419	295	7	40	450	263	673	6e-39	160
rs:WP_037549984	DNA topoisomerase III [Staphylococcus sp. TE8].	28.64	426	268	11	35	450	227	626	6e-39	159
rs:WP_041193069	DNA topoisomerase III, partial [Candidatus Profftella armatura].	30.08	379	246	9	32	399	250	620	6e-39	160
rs:WP_035508200	MULTISPECIES: DNA topoisomerase III [Halobacillus].	27.45	408	264	11	59	454	269	656	6e-39	159
tr:A0A0D6ISH5_ALCXX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.28	378	229	10	36	396	247	614	6e-39	160
tr:V5EIH7_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.43	350	217	10	56	397	60	394	6e-39	157
rs:WP_044289457	MULTISPECIES: DNA topoisomerase III [Robinsoniella].	32.17	373	219	13	57	400	282	649	6e-39	159
rs:WP_044784436	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	25.78	419	295	7	40	450	263	673	6e-39	160
rs:WP_047973623	DNA topoisomerase III, partial [Bacillus sp. LL01].	29.26	376	242	7	22	385	52	415	6e-39	158
rs:WP_044243489	DNA topoisomerase III, partial [Pantoea stewartii].	31.59	364	235	6	31	385	241	599	6e-39	159
tr:S5R840_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.08	379	246	9	32	399	250	620	6e-39	160
rs:WP_028790806	DNA topoisomerase III [Tetragenococcus muriaticus].	28.54	403	249	8	43	445	237	600	6e-39	159
tr:C5ER81_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.09	432	262	14	34	450	223	629	6e-39	159
rs:WP_026648650	DNA topoisomerase III [Blautia wexlerae].	30.58	363	240	5	33	392	220	573	6e-39	159
rs:WP_015535784	DNA topoisomerase III, bacteria and conjugative plasmid [Faecalitalea cylindroides].	30.23	430	264	14	34	450	221	627	6e-39	159
rs:WP_042253463	topoisomerase I [Lactobacillus brevis].	30.84	347	221	8	57	397	269	602	6e-39	159
rs:WP_027821235	DNA topoisomerase III [Lactobacillus plantarum].	31.58	380	231	11	33	399	241	604	6e-39	159
rs:WP_011010711	DNA topoisomerase [Clostridium perfringens].	30.23	430	257	14	40	452	253	656	6e-39	159
rs:WP_002204216	DNA topoisomerase I [Bacillus cereus].	27.23	426	289	10	35	454	239	649	6e-39	160
rs:WP_003207662	DNA topoisomerase I [Bacillus mycoides].	27.84	431	286	9	32	454	236	649	6e-39	160
rs:WP_033728948	DNA topoisomerase I [Bacillus weihenstephanensis].	27.70	426	287	10	35	454	239	649	7e-39	160
rs:WP_040381961	DNA topoisomerase III [Clostridiales bacterium 1_7_47FAA].	30.09	432	262	14	34	450	224	630	7e-39	159
tr:A0A096LKN5_9ACTN	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	32.12	411	243	12	59	445	247	645	7e-39	159
rs:WP_043485858	hypothetical protein, partial [Holophaga foetida].	29.43	367	240	7	47	398	255	617	7e-39	158
rs:WP_002478828	DNA topoisomerase III [Staphylococcus lugdunensis].	27.96	422	276	9	35	450	227	626	7e-39	159
rs:WP_026801823	DNA topoisomerase III [Pontibacillus halophilus].	28.29	410	258	12	59	454	270	657	7e-39	159
rs:WP_014216307	DNA topoisomerase III [Pediococcus claussenii].	31.58	380	231	11	33	399	241	604	7e-39	159
rs:WP_021900326	DNA topoisomerase [Eggerthella sp. CAG:1427].	33.23	334	203	8	60	391	264	579	7e-39	159
rs:WP_009203344	DNA topoisomerase [Anaerostipes hadrus].	28.96	404	254	7	26	428	224	595	7e-39	159
gp:CP001837_768	DNA topoisomerase III [Staphylococcus lugdunensis HKU09-01]	27.96	422	276	9	35	450	232	631	7e-39	159
rs:WP_035463497	DNA topoisomerase III [Lactobacillus ceti].	28.12	409	247	9	41	445	236	601	7e-39	159
rs:WP_002576947	DNA topoisomerase III [[Clostridium] bolteae].	31.34	367	230	8	40	396	228	582	7e-39	159
rs:WP_006775893	DNA topoisomerase III [Hungatella hathewayi].	30.22	407	251	11	34	425	224	612	7e-39	159
rs:WP_000520743	DNA topoisomerase I [Bacillus cereus].	27.46	426	288	10	35	454	239	649	7e-39	160
rs:WP_047185807	DNA topoisomerase III, partial [Bacilli bacterium VT-13-104].	31.49	343	222	6	61	399	268	601	7e-39	158
rs:WP_016370345	DNA topoisomerase III [Lactobacillus paracasei].	31.53	352	212	9	57	397	269	602	8e-39	159
rs:WP_002166603	DNA topoisomerase I [Bacillus cereus].	27.44	430	283	10	35	454	239	649	8e-39	160
tr:A0A0D3RLA6_LACRE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.32	348	220	8	56	397	268	602	8e-39	159
rs:WP_020366414	DNA topoisomerase III [Staphylococcus epidermidis].	28.87	426	269	10	34	450	226	626	8e-39	159
rs:WP_016475275	DNA topoisomerase III [Sutterella wadsworthensis].	32.27	409	223	14	40	425	256	633	8e-39	160
rs:WP_003600531	DNA topoisomerase III, partial [Lactobacillus casei].	30.88	353	217	9	57	399	227	562	8e-39	158
rs:WP_023567376	DNA topoisomerase III, partial [Escherichia coli].	40.31	191	112	2	36	226	251	439	8e-39	156
rs:WP_046481675	DNA topoisomerase, partial [Pseudomonas veronii].	30.52	367	226	9	40	384	254	613	8e-39	160
rs:WP_044593794	DNA topoisomerase III, partial [Cronobacter sakazakii].	40.93	193	112	2	36	228	251	441	8e-39	156
rs:WP_005434089	DNA topoisomerase III [Sutterella wadsworthensis].	32.60	365	201	9	40	385	255	593	8e-39	160
rs:WP_001995833	DNA topoisomerase III [Bacillus cereus].	25.78	419	295	7	40	450	263	673	8e-39	160
rs:WP_015499506	DNA recombination protein RmuC [Octadecabacter antarcticus].	33.05	354	215	11	38	377	232	577	8e-39	159
rs:WP_041592301	DNA topoisomerase III [Terribacillus aidingensis].	30.45	381	230	11	77	452	274	624	8e-39	158
rs:WP_003481996	DNA topoisomerase [Clostridium perfringens].	30.23	430	257	14	40	452	253	656	8e-39	159
rs:WP_011591016	DNA topoisomerase [Clostridium perfringens].	30.00	430	258	14	40	452	253	656	8e-39	159
tr:W7ZEF8_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.86	395	259	6	40	428	238	616	9e-39	159
rs:WP_004560848	DNA topoisomerase [Lactobacillus delbrueckii].	31.07	412	249	13	57	454	269	659	9e-39	159
rs:WP_000090078	DNA topoisomerase III [Bacillus thuringiensis].	30.40	375	234	7	60	425	251	607	9e-39	159
rs:WP_002453790	MULTISPECIES: DNA topoisomerase III [Staphylococcus].	28.40	426	269	11	35	450	227	626	9e-39	159
rs:WP_000520754	DNA topoisomerase I [Bacillus cereus].	27.23	426	289	10	35	454	239	649	9e-39	160
rs:WP_021361579	DNA topoisomerase III [Peptoclostridium difficile].	31.07	428	241	13	40	445	228	623	9e-39	159
rs:WP_047649273	DNA topoisomerase III [Enterococcus faecalis].	28.11	402	244	7	47	445	243	602	9e-39	158
rs:WP_016511107	DNA topoisomerase III [Lactobacillus plantarum].	31.56	377	231	12	33	397	241	602	9e-39	159
rs:WP_026707121	DNA topoisomerase I [Flavobacterium frigidarium].	31.79	324	210	5	71	393	273	586	9e-39	158
rs:WP_041941796	DNA topoisomerase, partial [Waddlia chondrophila].	30.45	381	245	9	27	404	220	583	9e-39	158
rs:WP_045352997	topoisomerase I [Lactobacillus plantarum].	31.83	377	230	12	33	397	241	602	9e-39	159
rs:WP_001094103	DNA topoisomerase III, partial [Bacillus cereus].	33.02	318	199	8	56	368	266	574	1e-38	157
rs:WP_033604845	DNA topoisomerase, partial [Enterococcus faecalis].	32.11	355	204	11	114	452	1	334	1e-38	155
rs:WP_005943447	DNA topoisomerase III [Faecalibacterium prausnitzii].	31.30	361	235	8	39	396	229	579	1e-38	158
rs:WP_022638687	topoisomerase IA [Lactobacillus plantarum].	29.42	452	262	17	33	454	241	665	1e-38	159
rs:WP_005429239	DNA topoisomerase III [Sutterella wadsworthensis].	32.27	409	223	14	40	425	256	633	1e-38	160
rs:WP_022118909	DNA topoisomerase III [Firmicutes bacterium CAG:56].	33.70	362	209	15	65	401	289	644	1e-38	158
rs:WP_046960179	DNA topoisomerase I [Bacillus cereus].	27.23	426	289	10	35	454	239	649	1e-38	160
tr:Q3MN26_LACPA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.73	353	212	10	56	397	268	602	1e-38	159
rs:WP_002825272	TraA family conjugation nicking enzyme, partial [Oenococcus oeni].	31.73	353	212	10	56	397	60	394	1e-38	157
rs:WP_000520752	DNA topoisomerase I [Bacillus thuringiensis].	27.12	424	292	9	35	454	239	649	1e-38	160
rs:WP_021738124	DNA topoisomerase [Eubacterium ramulus].	31.23	397	242	11	40	425	229	605	1e-38	158
rs:WP_003374314	DNA topoisomerase [Clostridium botulinum].	29.60	446	268	15	26	452	236	654	1e-38	159
tr:F8LD86_9CHLA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.45	381	245	9	27	404	220	583	1e-38	158
tr:J7YG53_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.23	426	289	10	35	454	239	649	1e-38	159
rs:WP_016103582	DNA topoisomerase III [Bacillus cereus].	27.17	427	288	10	35	454	239	649	1e-38	160
rs:WP_033143219	DNA topoisomerase III [Blautia producta].	30.71	407	254	10	31	425	218	608	1e-38	158
rs:WP_041501265	topoisomerase I [Lactobacillus heilongjiangensis].	30.99	355	210	9	57	397	269	602	1e-38	158
rs:WP_034688246	DNA topoisomerase [Enterococcus mundtii].	30.12	405	256	8	47	437	252	643	1e-38	158
rs:WP_002151036	DNA topoisomerase I [Bacillus cereus].	27.46	426	288	10	35	454	239	649	1e-38	160
rs:WP_023353350	DNA topoisomerase III [Catonella morbi].	30.10	412	246	10	47	445	235	617	1e-38	158
rs:WP_002819867	hypothetical protein [Oenococcus oeni].	31.34	351	216	9	56	397	60	394	1e-38	157
rs:WP_000520737	DNA topoisomerase I [Bacillus thuringiensis].	27.46	426	288	10	35	454	239	649	1e-38	160
rs:WP_038369398	hypothetical protein [Brackiella oedipodis].	31.65	417	233	15	26	425	222	603	1e-38	158
rs:WP_033603300	DNA topoisomerase, partial [Enterococcus faecalis].	33.14	347	214	7	52	392	127	461	1e-38	156
rs:WP_045091551	DNA topoisomerase III [Clostridium sp. FS41].	31.21	423	252	15	40	450	228	623	1e-38	158
rs:WP_009445426	DNA topoisomerase III [Lachnospiraceae bacterium oral taxon 082].	32.49	357	218	10	51	391	280	629	1e-38	158
rs:WP_006573250	DNA topoisomerase III [Pseudoflavonifractor capillosus].	30.07	419	255	11	40	445	228	621	1e-38	158
rs:WP_007039216	DNA topoisomerase III [Thiorhodococcus drewsii].	30.20	351	234	5	59	402	256	602	1e-38	159
rs:WP_007360327	DNA topoisomerase III [Opitutaceae bacterium TAV1].	32.28	381	223	14	30	385	248	618	1e-38	160
rs:WP_004457833	DNA topoisomerase [Clostridium perfringens].	30.00	430	258	14	40	452	253	656	1e-38	158
rs:WP_023351307	MULTISPECIES: DNA topoisomerase 3 [Staphylococcus].	28.64	426	268	11	35	450	227	626	1e-38	158
rs:WP_002610336	MULTISPECIES: DNA topoisomerase III [Firmicutes].	30.99	426	244	12	40	445	228	623	1e-38	158
rs:WP_048340536	topoisomerase I [Lactobacillus fermentum].	31.43	350	217	10	56	397	268	602	1e-38	158
rs:WP_008391092	DNA topoisomerase III [Clostridium sp. SS2/1].	28.86	402	253	7	28	428	226	595	1e-38	158
rs:WP_045497641	DNA topoisomerase I [Chryseobacterium sp. StRB126].	31.30	345	226	5	48	391	250	584	1e-38	158
rs:WP_022376747	DNA topoisomerase III [Clostridium sp. CAG:62].	29.56	433	246	12	3	402	247	653	1e-38	158
rs:WP_005921736	DNA topoisomerase III [Faecalibacterium prausnitzii].	32.55	424	242	17	37	445	214	608	1e-38	158
rs:WP_034947418	DNA topoisomerase III [Candidatus Accumulibacter sp. SK-02].	30.89	395	228	10	65	435	279	652	1e-38	159
rs:WP_032509776	DNA topoisomerase III [Peptoclostridium difficile].	31.99	372	220	7	40	396	228	581	1e-38	158
rs:WP_042978736	DNA topoisomerase I [Bacillus mycoides].	27.61	431	287	9	32	454	236	649	2e-38	159
rs:WP_029162866	DNA topoisomerase III [Clostridium scatologenes].	30.99	355	222	9	60	399	295	641	2e-38	159
rs:WP_035785837	DNA topoisomerase [Clostridium botulinum].	29.60	446	268	15	26	452	236	654	2e-38	158
rs:WP_003461793	DNA topoisomerase [Clostridium perfringens].	29.77	430	259	14	40	452	253	656	2e-38	158
tr:A0A078MCC0_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.13	412	245	10	59	454	270	650	2e-38	158
rs:WP_024854553	DNA topoisomerase III [[Ruminococcus] gnavus].	30.89	382	242	12	72	438	299	673	2e-38	157
rs:WP_039106709	topoisomerase I [Lactobacillus brevis].	31.82	352	211	10	57	397	269	602	2e-38	158
tr:Q0SRJ7_CLOPS	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ABG87621.1};	29.77	430	259	14	40	452	253	656	2e-38	158
tr:D4N0D7_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.86	402	253	7	28	428	226	595	2e-38	158
rs:WP_012621109	DNA topoisomerase III [Lactobacillus gasseri].	31.52	349	216	10	57	397	270	603	2e-38	158
rs:WP_013978336	DNA topoisomerase III [Clostridium sp. SY8519].	31.66	379	227	11	41	399	274	640	2e-38	157
tr:D5HIG2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.38	418	268	10	33	445	221	620	2e-38	158
rs:WP_003455196	DNA topoisomerase [Clostridium perfringens].	30.39	431	255	15	40	452	253	656	2e-38	158
rs:WP_043933664	DNA topoisomerase [Bacillus sp. EB01].	29.48	424	262	12	40	450	253	652	2e-38	158
rs:WP_026195590	topoisomerase I [Verrucomicrobium sp. 3C].	30.16	378	231	10	23	385	241	600	2e-38	159
rs:WP_036185771	hypothetical protein, partial [Lysinibacillus manganicus].	28.25	400	264	7	37	428	230	614	2e-38	157
rs:WP_026477045	DNA topoisomerase III [Alkaliphilus transvaalensis].	32.60	365	205	12	61	399	289	638	2e-38	157
gpu:CP011222_681	DNA topoisomerase III [[Haemophilus] ducreyi]	45.18	166	91	0	69	234	278	443	2e-38	156
rs:WP_042749367	topoisomerase I [Lactobacillus brevis].	31.82	352	211	10	57	397	269	602	2e-38	158
gpu:CP011227_656	DNA topoisomerase III [[Haemophilus] ducreyi]	45.18	166	91	0	69	234	278	443	2e-38	156
rs:WP_003451558	DNA topoisomerase [Clostridium perfringens].	30.00	430	258	14	40	452	253	656	2e-38	158
rs:WP_010944885	DNA topoisomerase III [[Haemophilus] ducreyi].	45.18	166	91	0	69	234	278	443	2e-38	156
rs:WP_000520726	DNA topoisomerase I [Bacillus cereus].	27.23	426	289	10	35	454	239	649	2e-38	159
rs:WP_009220366	DNA topoisomerase III [Lachnospiraceae oral taxon 107].	30.10	412	246	10	47	445	235	617	2e-38	157
rs:WP_033798183	DNA topoisomerase I [Bacillus mycoides].	27.84	431	286	10	32	454	236	649	2e-38	159
rs:WP_039061692	DNA topoisomerase III, partial [Shigella flexneri].	34.10	261	159	3	69	320	3	259	2e-38	151
rs:WP_008665854	DNA topoisomerase I [Bacteroides sp. 4_1_36].	32.07	396	243	11	35	427	238	610	2e-38	157
rs:WP_033694064	DNA topoisomerase III [Bacillus cereus].	31.87	364	224	9	65	425	269	611	2e-38	157
rs:WP_016296807	hypothetical protein [Lachnospiraceae bacterium M18-1].	32.75	345	206	10	72	392	326	668	2e-38	157
rs:WP_034930384	DNA topoisomerase III [Candidatus Accumulibacter sp. SK-01].	30.62	418	248	12	40	435	255	652	2e-38	159
rs:WP_044995209	DNA topoisomerase III [Lachnospiraceae bacterium JC7].	31.18	372	223	13	59	401	292	659	2e-38	157
rs:WP_002823696	DNA topoisomerase [Oenococcus oeni].	31.84	380	226	12	33	397	33	394	2e-38	156
rs:WP_025653856	DNA topoisomerase III [Clostridiales bacterium VE202-21].	30.98	397	243	11	40	425	229	605	2e-38	157
rs:WP_015364790	MULTISPECIES: DNA topoisomerase III [Staphylococcus].	28.44	422	277	10	34	450	226	627	2e-38	157
rs:WP_022250918	DNA topoisomerase III [Clostridium nexile CAG:348].	31.82	374	213	14	47	392	271	630	2e-38	157
rs:WP_002594223	DNA topoisomerase III [[Clostridium] clostridioforme].	31.35	421	261	11	34	444	222	624	2e-38	157
rs:WP_002825295	DNA topoisomerase III [Oenococcus oeni].	31.48	378	230	11	33	397	241	602	2e-38	157
rs:WP_016128424	DNA topoisomerase III [Bacillus cereus].	27.23	426	289	10	35	454	239	649	2e-38	159
rs:WP_002187829	DNA topoisomerase I [Bacillus cereus].	27.23	426	289	10	35	454	239	649	2e-38	159
rs:WP_002457943	DNA topoisomerase III [Staphylococcus epidermidis].	28.87	426	269	10	34	450	226	626	2e-38	157
tr:A0A0A7U658_LACBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.75	348	222	9	56	397	268	602	2e-38	157
rs:WP_022268381	DNA topoisomerase [Firmicutes bacterium CAG:424].	33.43	341	206	11	74	395	301	639	2e-38	157
rs:WP_016526810	DNA topoisomerase [Lactobacillus plantarum].	31.25	352	213	9	57	397	269	602	2e-38	157
gp:CP008816_932	DNA topoisomerase III family protein [Enterococcus faecalis ATCC 29212]	28.11	402	244	7	47	445	207	566	2e-38	157
rs:WP_040118784	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	27.48	433	285	10	32	454	236	649	2e-38	159
tr:C2UN45_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.93	439	277	13	29	448	252	674	2e-38	158
rs:WP_002447325	DNA topoisomerase III [Staphylococcus epidermidis].	28.87	426	269	10	34	450	226	626	2e-38	157
rs:WP_017211802	MULTISPECIES: DNA topoisomerase [Clostridium].	31.21	423	245	16	48	452	261	655	2e-38	157
rs:WP_003308699	DNA topoisomerase III [Bacillus thuringiensis].	31.59	364	225	9	65	425	269	611	2e-38	157
rs:WP_002585520	DNA topoisomerase III [[Clostridium] clostridioforme].	28.98	421	258	14	37	445	225	616	2e-38	157
tr:D4KBC0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.68	423	251	15	37	447	60	456	3e-38	156
tr:W7ZTL7_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAF20066.1};	33.55	310	184	10	160	459	19	316	3e-38	154
rs:WP_006859375	DNA topoisomerase III [Roseburia intestinalis].	30.92	401	245	9	56	445	245	624	3e-38	157
rs:WP_036297314	DNA topoisomerase [Methylobacter whittenburyi].	32.60	362	226	10	39	395	233	581	3e-38	158
rs:WP_027640143	DNA topoisomerase [Clostridium cadaveris].	28.54	445	274	13	26	452	236	654	3e-38	157
rs:WP_044960776	DNA topoisomerase III [Shuttleworthia sp. MSX8B].	33.16	389	206	14	59	401	349	729	3e-38	158
rs:WP_003470899	DNA topoisomerase [Clostridium perfringens].	29.77	430	259	14	40	452	253	656	3e-38	157
rs:WP_038535745	DNA topoisomerase [Bacillus sp. X1(2014)].	29.93	431	260	13	36	450	249	653	3e-38	157
rs:WP_021393615	DNA topoisomerase III family protein [Peptoclostridium difficile].	32.06	340	216	5	43	378	231	559	3e-38	157
rs:WP_036204228	hypothetical protein, partial [Lysinibacillus sinduriensis].	28.77	424	270	10	36	450	228	628	3e-38	157
rs:WP_010739950	DNA topoisomerase III [Enterococcus malodoratus].	27.38	409	256	7	41	449	235	602	3e-38	157
rs:WP_002499566	DNA topoisomerase III [Staphylococcus epidermidis].	28.87	426	269	10	34	450	226	626	3e-38	157
rs:WP_002491551	DNA topoisomerase III [Staphylococcus epidermidis].	28.87	426	269	10	34	450	226	626	3e-38	157
rs:WP_046044421	topoisomerase [Staphylococcus epidermidis].	28.87	426	269	10	34	450	226	626	3e-38	157
tr:A0A061NZC6_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.30	409	245	12	59	454	276	661	3e-38	157
rs:WP_033591622	DNA topoisomerase III [Enterococcus faecalis].	28.18	401	245	7	47	445	243	602	3e-38	157
rs:WP_003478477	DNA topoisomerase [Clostridium perfringens].	29.77	430	259	14	40	452	253	656	3e-38	157
rs:WP_022233498	DNA topoisomerase III [Bacteroides sp. CAG:443].	29.28	362	244	8	37	396	230	581	3e-38	157
rs:WP_010749200	DNA topoisomerase III, partial [Enterococcus casseliflavus].	33.56	298	176	7	52	342	264	546	3e-38	156
rs:WP_016317479	DNA topoisomerase III, partial [Anaerotruncus sp. G3(2012)].	31.18	340	217	6	40	371	39	369	3e-38	153
rs:WP_033700641	DNA topoisomerase, partial [Enterococcus faecium].	31.97	391	238	10	52	428	264	640	3e-38	156
tr:C7GHN5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.12	421	261	12	34	445	104	504	3e-38	156
tr:A0A0A7U5Q4_LACBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.77	377	234	11	33	397	46	407	3e-38	155
rs:WP_036248694	DNA topoisomerase [Methylobacter sp. BBA5.1].	32.32	362	227	10	39	395	233	581	4e-38	157
rs:WP_002374513	DNA topoisomerase III [Enterococcus faecalis].	27.02	433	269	8	18	445	212	602	4e-38	157
rs:WP_044315429	DNA topoisomerase III, partial [Pseudomonas stutzeri].	36.94	222	139	1	187	408	2	222	4e-38	150
rs:WP_000280351	hypothetical protein [Bacillus cereus].	28.93	439	277	13	29	448	256	678	4e-38	157
rs:WP_022263573	DNA topoisomerase III [Butyrivibrio sp. CAG:318].	29.82	436	248	16	3	401	248	662	4e-38	157
rs:WP_022037158	DNA topoisomerase III [Ruminococcus gnavus CAG:126].	30.53	380	246	10	72	438	299	673	4e-38	156
rs:WP_032834767	DNA topoisomerase [Fusobacterium sp. OBRC1].	27.13	387	245	8	74	446	271	634	4e-38	157
rs:WP_002414495	DNA topoisomerase III [Enterococcus faecalis].	28.11	402	244	7	47	445	243	602	4e-38	157
rs:WP_011968211	DNA topoisomerase [Clostridium beijerinckii].	31.21	423	245	16	48	452	261	655	4e-38	157
rs:WP_033154848	DNA topoisomerase, partial [Pseudobutyrivibrio ruminis].	29.67	418	239	14	70	446	295	698	4e-38	157
rs:WP_000520742	hypothetical protein [Bacillus cereus].	27.36	424	287	10	37	454	241	649	4e-38	158
rs:WP_033625995	DNA topoisomerase III [Enterococcus faecalis].	27.08	432	270	8	18	445	212	602	4e-38	157
rs:WP_041894446	DNA topoisomerase [Clostridium beijerinckii].	31.21	423	245	16	48	452	261	655	4e-38	157
rs:WP_005642341	DNA topoisomerase I [Parabacteroides merdae].	31.82	396	244	11	35	427	238	610	4e-38	157
tr:J9GR19_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJX04953.1};	33.22	289	179	8	117	401	2	280	4e-38	153
rs:WP_002191962	DNA topoisomerase I [Bacillus cereus].	27.44	430	283	10	35	454	239	649	4e-38	158
rs:WP_033874305	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	39.20	176	105	1	74	247	1	176	4e-38	147
tr:E0GLT5_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.02	433	269	8	18	445	268	658	4e-38	157
rs:WP_044999629	DNA topoisomerase III [Roseburia intestinalis].	31.12	421	261	12	34	445	90	490	4e-38	155
tr:V2Y4D4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.02	356	203	11	74	396	299	648	4e-38	156
rs:WP_010820938	DNA topoisomerase III [Enterococcus faecalis].	26.79	433	270	8	18	445	212	602	4e-38	156
rs:WP_029321244	DNA topoisomerase III, partial [Butyrivibrio sp. AE3004].	30.61	428	234	15	22	400	245	658	4e-38	156
rs:WP_000520739	DNA topoisomerase I [Bacillus cereus].	27.23	426	289	10	35	454	239	649	5e-38	158
rs:WP_016107050	DNA topoisomerase III [Bacillus cereus].	27.44	430	283	10	35	454	239	649	5e-38	158
rs:WP_002366910	DNA topoisomerase III [Enterococcus faecalis].	27.08	432	270	8	18	445	212	602	5e-38	156
rs:WP_033657898	DNA topoisomerase III [Enterococcus faecalis].	28.18	401	245	7	47	445	243	602	5e-38	156
rs:WP_021640983	DNA topoisomerase III [[Clostridium] symbiosum].	32.64	383	216	14	49	392	276	655	5e-38	156
rs:WP_005539987	DNA topoisomerase III [Johnsonella ignava].	31.47	394	209	15	58	392	279	670	5e-38	156
rs:WP_038812454	topoisomerase [Staphylococcus epidermidis].	28.64	426	270	10	34	450	226	626	5e-38	156
rs:WP_044923300	DNA topoisomerase III [Lachnospiraceae bacterium MA2020].	30.67	375	230	9	45	396	274	641	5e-38	156
rs:WP_039730506	DNA topoisomerase, partial [Enterococcus mundtii].	29.88	405	257	8	47	437	182	573	5e-38	156
tr:A0A0A1H2H0_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.03	377	233	11	33	397	243	604	5e-38	156
rs:WP_025219815	DNA topoisomerase III [Lysinibacillus varians].	30.12	415	246	13	59	455	269	657	5e-38	156
rs:WP_048390613	DNA topoisomerase III [Lysinibacillus sp. LK3].	31.37	408	249	14	59	455	269	656	5e-38	156
rs:WP_045724140	DNA topoisomerase [Clostridium baratii].	29.30	430	266	13	36	452	250	654	5e-38	156
tr:X5NVB0_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.79	433	270	8	18	445	162	552	5e-38	156
rs:WP_033615628	DNA topoisomerase, partial [Enterococcus faecium].	32.95	349	212	8	52	392	40	374	5e-38	153
rs:WP_030091797	hypothetical protein, partial [Sphingomonas sp. DC-6].	32.73	330	203	8	69	387	266	587	5e-38	156
rs:WP_044935049	DNA topoisomerase, partial [Pseudobutyrivibrio sp. LB2011].	29.67	418	239	14	70	446	295	698	5e-38	157
rs:WP_009092112	DNA topoisomerase [Elizabethkingia anophelis].	26.93	427	284	10	24	446	216	618	6e-38	156
tr:C3FBJ1_BACTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.23	426	289	10	35	454	239	649	6e-38	157
rs:WP_041095836	topoisomerase I [Lactobacillus hokkaidonensis].	31.03	377	233	11	33	397	241	602	6e-38	156
rs:WP_024360979	DNA topoisomerase III [Lysinibacillus sphaericus].	30.10	412	250	13	59	455	269	657	6e-38	156
rs:WP_013378047	ATP-dependent DNA helicase RecQ [Stigmatella aurantiaca].	29.55	379	242	5	43	398	285	661	6e-38	159
rs:WP_044942700	DNA topoisomerase III [Blautia schinkii].	31.54	371	229	8	40	400	230	585	6e-38	156
rs:WP_002349703	DNA topoisomerase, partial [Enterococcus faecium].	33.65	312	192	6	57	365	129	428	6e-38	154
rs:WP_048375760	DNA topoisomerase I [Bacillus sp. LK2].	27.23	426	289	10	35	454	239	649	6e-38	158
rs:WP_039314343	DNA topoisomerase [Clostridium baratii].	30.09	432	260	15	36	452	250	654	6e-38	156
tr:Q099E1_STIAD	SubName: Full=Topoisomerase B {ECO:0000313|EMBL:EAU68374.1};	29.55	379	242	5	43	398	290	666	6e-38	159
rs:WP_002496109	DNA topoisomerase III [Staphylococcus epidermidis].	28.87	426	269	10	34	450	226	626	6e-38	156
rs:WP_037440266	DNA topoisomerase I [Pedobacter antarcticus].	30.35	369	235	7	24	391	237	584	6e-38	156
rs:WP_014248119	DNA topoisomerase III [Azospirillum lipoferum].	31.48	359	206	12	67	392	258	609	6e-38	157
rs:WP_002466483	DNA topoisomerase III [Staphylococcus warneri].	28.20	422	278	10	34	450	226	627	6e-38	156
rs:WP_025966435	DNA topoisomerase I [Bacillus cereus].	27.23	426	289	10	35	454	239	649	6e-38	157
tr:E2ZFS1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.75	400	247	11	39	428	165	544	6e-38	155
rs:WP_002503703	DNA topoisomerase III [Staphylococcus epidermidis].	29.15	422	273	10	34	450	226	626	6e-38	156
rs:WP_021651108	DNA topoisomerase III [Blautia sp. KLE 1732].	30.60	366	222	11	56	393	281	642	6e-38	156
rs:WP_035546994	DNA topoisomerase III [Halobacillus sp. BBL2006].	27.52	407	265	10	59	454	270	657	6e-38	156
rs:WP_022153122	DNA topoisomerase [Firmicutes bacterium CAG:65].	29.26	417	249	13	3	392	245	642	6e-38	156
rs:WP_015474608	DNA topoisomerase III [Lactobacillus brevis].	31.52	349	216	10	57	397	269	602	6e-38	156
tr:E2ZN59_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.86	408	243	12	48	445	1	383	6e-38	154
rs:WP_016911088	hypothetical protein [Staphylococcus vitulinus].	28.74	421	263	12	40	450	234	627	7e-38	156
rs:WP_002164824	DNA topoisomerase III [Bacillus cereus].	31.59	364	225	9	65	425	269	611	7e-38	156
rs:WP_021349356	DNA topoisomerase III [Lactobacillus fermentum].	31.25	352	213	9	57	397	269	602	7e-38	156
rs:WP_042688348	hypothetical protein [Candidatus Glomeribacter gigasporarum].	36.87	217	131	3	34	249	238	449	7e-38	154
rs:WP_039107789	topoisomerase I [Lactobacillus brevis].	31.16	353	214	8	56	397	268	602	7e-38	156
rs:WP_010781442	DNA topoisomerase III [Enterococcus gilvus].	27.14	409	257	7	41	449	235	602	7e-38	156
rs:WP_005935077	DNA topoisomerase III [Faecalibacterium prausnitzii].	30.64	408	254	12	39	428	229	625	7e-38	156
gp:HE963029_27	DNA topoisomerase (pseudogene) [Enterococcus faecium]	31.49	362	232	7	40	396	230	580	7e-38	156
rs:WP_046648653	DNA topoisomerase I [Bacillus cereus].	26.65	424	294	9	35	454	239	649	7e-38	157
rs:WP_038987553	DNA topoisomerase I [Myroides odoratimimus].	28.84	378	248	9	49	424	251	609	7e-38	156
tr:R3QFQ2_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOL03019.1}; Flags: Fragment;	32.70	315	182	9	151	452	26	323	7e-38	151
rs:WP_010735485	DNA topoisomerase III [Enterococcus mundtii].	29.63	405	258	8	47	437	252	643	7e-38	156
rs:WP_033607115	DNA topoisomerase, partial [Enterococcus faecalis].	32.48	351	211	8	52	392	264	598	7e-38	155
rs:WP_035197261	DNA topoisomerase [Bacillus azotoformans].	30.44	427	259	15	36	450	249	649	7e-38	156
tr:S4NK75_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.18	340	211	10	56	387	10	334	8e-38	151
rs:WP_033701090	DNA topoisomerase III, partial [Enterococcus faecium].	31.49	362	232	7	40	396	209	559	8e-38	155
rs:WP_009530372	DNA topoisomerase III [Peptostreptococcaceae bacterium OBRC8].	29.27	410	266	8	40	445	228	617	8e-38	155
rs:WP_045152232	DNA topoisomerase III, partial [Escherichia coli].	30.06	356	221	7	120	459	1	344	8e-38	154
tr:G2JB72_9BURK	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:CCD30025.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CCD30025.1};	36.87	217	131	3	34	249	254	465	8e-38	154
rs:WP_041142920	topoisomerase I, partial [Lactobacillus plantarum].	31.22	378	231	11	33	397	241	602	8e-38	155
rs:WP_023519649	topoisomerase [Enterococcus mundtii].	29.63	405	258	8	47	437	252	643	8e-38	156
tr:E6FP47_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.18	401	245	7	47	445	299	658	8e-38	156
rs:WP_041691717	hypothetical protein, partial [Eggerthella lenta].	31.87	411	244	12	59	445	247	645	8e-38	156
rs:WP_022426265	DNA topoisomerase [Ruminococcus sp. CAG:90].	30.41	365	224	11	56	393	269	630	8e-38	155
rs:WP_002377042	DNA topoisomerase III [Enterococcus faecalis].	27.86	402	245	7	47	445	243	602	9e-38	155
rs:WP_012419946	DNA topoisomerase III [Akkermansia muciniphila].	30.39	362	220	9	40	385	259	604	9e-38	157
rs:WP_044953325	DNA topoisomerase III [Faecalibacterium prausnitzii].	30.75	400	247	11	39	428	95	474	9e-38	155
rs:WP_002163405	DNA topoisomerase III [Bacillus cereus].	30.96	365	226	9	65	425	269	611	9e-38	155
rs:WP_015639749	DNA topoisomerase III [Lactobacillus plantarum].	31.22	378	231	11	33	397	241	602	9e-38	155
rs:WP_016218703	DNA topoisomerase III [Dorea sp. 5-2].	29.34	426	242	15	22	392	228	649	9e-38	155
rs:WP_010823795	DNA topoisomerase III [Enterococcus faecalis].	26.79	433	270	8	18	445	212	602	9e-38	155
rs:WP_022396805	DNA topoisomerase III [Akkermansia sp. CAG:344].	30.11	362	221	9	40	385	259	604	9e-38	157
tr:C8WNM4_EGGLE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.87	411	244	12	59	445	247	645	9e-38	156
rs:WP_005927750	DNA topoisomerase III [Faecalibacterium prausnitzii].	30.48	397	252	10	39	428	229	608	9e-38	155
rs:WP_031555562	DNA topoisomerase III [Lachnospira multipara].	28.64	405	253	14	43	413	267	669	9e-38	155
tr:Q3ES69_BACTI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.00	400	267	10	61	454	8	392	1e-37	155
rs:WP_010818429	DNA topoisomerase III [Enterococcus faecalis].	27.86	402	245	7	47	445	243	602	1e-37	155
rs:WP_034217873	DNA topoisomerase III [Lachnospiraceae bacterium AB2028].	30.04	466	257	16	3	422	246	688	1e-37	155
rs:WP_008427758	topoisomerase IA [Clostridium sp. Maddingley MBC34-26].	31.03	448	258	18	27	452	237	655	1e-37	155
rs:WP_009244366	DNA topoisomerase III [Lachnospiraceae bacterium 2_1_58FAA].	31.51	365	228	10	72	417	236	597	1e-37	155
rs:WP_007857917	DNA topoisomerase III [[Clostridium] citroniae].	29.14	405	238	12	35	392	264	666	1e-37	155
rs:WP_002372058	DNA topoisomerase III [Enterococcus faecalis].	26.79	433	270	8	18	445	212	602	1e-37	155
rs:WP_002369154	DNA topoisomerase III [Enterococcus faecalis].	26.85	432	271	8	18	445	212	602	1e-37	155
rs:WP_033656229	DNA topoisomerase III [Enterococcus faecalis].	27.86	402	245	7	47	445	243	602	1e-37	155
rs:WP_016185174	DNA topoisomerase III [Enterococcus sulfureus].	30.62	369	230	10	93	452	306	657	1e-37	155
rs:WP_007705937	DNA topoisomerase III [[Clostridium] asparagiforme].	32.11	380	231	11	55	425	244	605	1e-37	155
rs:WP_016513361	DNA topoisomerase III [Bacillus cereus].	27.00	426	290	10	35	454	239	649	1e-37	157
tr:A0A0C2D1G0_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.63	377	227	12	59	414	277	647	1e-37	158
rs:WP_002576397	DNA topoisomerase III [[Clostridium] bolteae].	31.27	403	237	12	40	426	228	606	1e-37	155
rs:WP_010828882	DNA topoisomerase III [Enterococcus faecalis].	27.86	402	245	7	47	445	243	602	1e-37	155
rs:WP_002362072	DNA topoisomerase III [Enterococcus faecalis].	27.86	402	245	7	47	445	243	602	1e-37	155
rs:WP_022207365	DNA topoisomerase [Eubacterium sp. CAG:252].	29.14	374	213	11	59	392	286	647	1e-37	155
rs:WP_016090829	DNA topoisomerase III [Bacillus cereus].	26.76	426	291	10	35	454	239	649	1e-37	157
rs:WP_035762558	DNA topoisomerase [Clostridium butyricum].	31.19	420	244	14	50	452	263	654	1e-37	155
rs:WP_004068688	DNA topoisomerase III [Clostridium sp. ASF502].	32.09	374	227	11	41	392	279	647	1e-37	155
rs:WP_045092577	DNA topoisomerase III [Clostridium sp. FS41].	29.14	405	238	12	35	392	264	666	1e-37	155
rs:WP_002317284	MULTISPECIES: DNA topoisomerase III [Bacteria].	31.49	362	232	7	40	396	230	580	1e-37	155
rs:WP_010815836	DNA topoisomerase III [Enterococcus faecalis].	26.79	433	270	8	18	445	212	602	1e-37	155
rs:WP_041072541	DNA topoisomerase III [Bacillus sp. OxB-1].	29.74	417	255	14	58	456	266	662	1e-37	155
rs:WP_010746590	DNA topoisomerase III [Enterococcus raffinosus].	27.14	409	257	7	41	449	235	602	1e-37	155
rs:WP_047021715	topoisomerase I, partial [Lactobacillus brevis].	31.16	353	212	9	57	397	100	433	1e-37	154
rs:WP_033656182	DNA topoisomerase III [Enterococcus faecalis].	27.86	402	245	7	47	445	243	602	1e-37	155
rs:WP_002388224	DNA topoisomerase III [Enterococcus faecalis].	27.86	402	245	7	47	445	243	602	1e-37	155
rs:WP_010710575	DNA topoisomerase III [Enterococcus faecalis].	27.86	402	245	7	47	445	243	602	1e-37	155
rs:WP_025480891	DNA topoisomerase, partial [Enterococcus faecium].	33.65	312	192	6	57	365	87	386	1e-37	154
rs:WP_033627478	DNA topoisomerase III [Enterococcus faecalis].	27.86	402	245	7	47	445	243	602	1e-37	155
rs:WP_003510596	MULTISPECIES: DNA topoisomerase III [Clostridiales].	32.38	383	217	14	49	392	276	655	1e-37	155
rs:WP_034233149	DNA topoisomerase III [Lachnospiraceae bacterium AC2029].	30.17	358	210	9	72	392	305	659	1e-37	155
rs:WP_033709859	MULTISPECIES: DNA topoisomerase I, partial [Bacillus cereus group].	28.00	400	267	10	61	454	5	389	1e-37	155
rs:WP_027829209	hypothetical protein [Lactobacillus harbinensis].	31.51	438	246	12	22	445	230	627	1e-37	155
rs:WP_041531187	hypothetical protein, partial [Persephonella marina].	31.32	348	194	10	62	396	257	572	1e-37	154
rs:WP_033727875	DNA topoisomerase I, partial [Bacillus weihenstephanensis].	28.00	400	267	10	61	454	4	388	1e-37	154
rs:WP_019484415	hypothetical protein, partial [Pseudomonas aeruginosa].	37.68	207	122	2	36	238	197	400	1e-37	152
tr:E6ILE0_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.79	433	270	8	18	445	268	658	1e-37	155
rs:WP_010777799	DNA topoisomerase III [Enterococcus faecalis].	27.93	401	246	7	47	445	243	602	1e-37	155
tr:E0GCU2_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.79	433	270	8	18	445	268	658	1e-37	155
rs:WP_010708822	DNA topoisomerase III [Enterococcus faecalis].	27.86	402	245	7	47	445	243	602	1e-37	155
rs:WP_016121209	DNA topoisomerase III [Bacillus cereus].	27.38	431	288	9	32	454	236	649	1e-37	157
rs:WP_014893884	DNA topoisomerase I [Bacillus cereus].	28.21	429	281	12	35	454	239	649	1e-37	156
rs:WP_044954273	DNA topoisomerase III, partial [Faecalibacterium prausnitzii].	31.93	404	240	12	52	445	2	380	1e-37	153
rs:WP_029740844	DNA topoisomerase III, partial [Enterobacter asburiae].	34.57	269	171	2	36	303	243	507	1e-37	154
rs:WP_027430564	DNA topoisomerase III [Lachnospira multipara].	29.89	358	227	11	57	392	284	639	1e-37	155
rs:WP_022197248	DNA topoisomerase III [Akkermansia muciniphila CAG:154].	30.39	362	220	9	40	385	259	604	1e-37	157
rs:WP_004320647	DNA topoisomerase I [Bacteroides ovatus].	31.44	369	230	9	60	427	263	609	1e-37	155
rs:WP_002380452	DNA topoisomerase III [Enterococcus faecalis].	27.86	402	245	7	47	445	243	602	1e-37	155
tr:J6WY89_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.65	312	192	6	57	365	87	386	1e-37	154
rs:WP_002366151	DNA topoisomerase, partial [Enterococcus faecium].	33.65	312	192	6	57	365	129	428	1e-37	154
rs:WP_029656511	DNA topoisomerase, partial [Enterococcus faecalis].	33.43	350	209	9	52	392	40	374	1e-37	152
tr:E2YTF1_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.79	433	270	8	18	445	268	658	1e-37	155
rs:WP_033591694	DNA topoisomerase III [Enterococcus faecalis].	26.85	432	271	8	18	445	212	602	1e-37	155
rs:WP_002356968	MULTISPECIES: DNA topoisomerase III [Enterococcus].	27.93	401	246	7	47	445	243	602	1e-37	155
rs:WP_000520738	DNA topoisomerase I [Bacillus cereus].	27.23	426	289	10	35	454	239	649	1e-37	157
tr:E0H3Y9_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.86	402	245	7	47	445	299	658	1e-37	155
rs:WP_002364251	DNA topoisomerase III [Enterococcus faecalis].	27.86	402	245	7	47	445	243	602	2e-37	155
rs:WP_029453315	DNA topoisomerase III [Clostridium algidicarnis].	29.67	364	225	10	54	406	266	609	2e-37	154
rs:WP_022744481	DNA topoisomerase 3 [Clostridium saccharobutylicum].	30.53	452	268	15	20	452	230	654	2e-37	155
rs:WP_009264856	DNA topoisomerase III [Lachnospiraceae bacterium 5_1_63FAA].	28.71	404	255	7	26	428	224	595	2e-37	155
rs:WP_044947806	DNA topoisomerase III [Blautia schinkii].	30.57	386	234	12	47	400	271	654	2e-37	155
tr:M3GG24_9STRE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.11	302	184	7	77	372	2	291	2e-37	149
rs:WP_047334783	DNA topoisomerase III [Enterococcus cecorum].	27.08	384	240	6	47	428	241	586	2e-37	155
rs:WP_004228801	DNA topoisomerase III [Lysinibacillus fusiformis].	31.37	408	249	15	59	455	269	656	2e-37	155
rs:WP_004461886	DNA topoisomerase III [[Clostridium] symbiosum].	32.38	383	217	14	49	392	276	655	2e-37	155
rs:WP_033496031	DNA topoisomerase III [Bifidobacterium biavatii].	31.63	430	244	13	49	445	241	653	2e-37	155
rs:WP_009168861	DNA topoisomerase [Clostridium sp. DL-VIII].	31.60	424	242	16	48	452	261	655	2e-37	155
rs:WP_010715326	DNA topoisomerase III [Enterococcus faecalis].	27.93	401	246	7	47	445	243	602	2e-37	155
rs:WP_010773489	DNA topoisomerase III [Enterococcus faecalis].	27.75	400	248	6	47	445	243	602	2e-37	155
rs:WP_046811118	topoisomerase I [Lactobacillus plantarum].	30.75	348	222	9	56	397	268	602	2e-37	155
rs:WP_036978530	DNA topoisomerase, partial [Pseudobutyrivibrio sp. MD2005].	28.93	439	261	14	47	446	272	698	2e-37	155
tr:A0A098EYV3_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.31	419	248	15	48	450	261	651	2e-37	155
tr:E6FJ07_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.79	433	270	8	18	445	268	658	2e-37	155
rs:WP_020561698	hypothetical protein [Methylosarcina fibrata].	29.97	387	259	7	11	396	206	581	2e-37	155
rs:WP_002475810	DNA topoisomerase III [Staphylococcus epidermidis].	28.64	426	270	10	34	450	226	626	2e-37	155
tr:E6ICX1_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.86	402	245	7	47	445	299	658	2e-37	155
rs:WP_043052453	DNA topoisomerase [Streptococcus equi].	29.43	384	237	10	86	455	298	661	2e-37	155
rs:WP_034439060	DNA topoisomerase [Candidatus Clostridium anorexicamassiliense].	30.73	371	226	11	40	398	252	603	2e-37	154
tr:F2MQ93_ENTFO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.85	432	271	8	18	445	268	658	2e-37	155
tr:D4K6W0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.17	411	250	12	39	428	95	489	2e-37	154
rs:WP_028068979	DNA topoisomerase I [Sphingobacterium thalpophilum].	30.08	369	236	7	24	391	237	584	2e-37	155
rs:WP_024725165	hypothetical protein [Clostridiales bacterium VE202-03].	28.98	383	258	9	61	432	247	626	2e-37	155
rs:WP_023924313	DNA topoisomerase III [[Ruminococcus] gnavus].	31.51	365	228	10	72	417	299	660	2e-37	154
tr:D4ELR4_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.85	432	271	8	18	445	268	658	2e-37	155
rs:WP_010822981	DNA topoisomerase III [Enterococcus faecalis].	27.86	402	245	7	47	445	243	602	2e-37	154
rs:WP_035040382	hypothetical protein, partial [Catonella morbi].	33.23	337	186	11	74	377	299	629	2e-37	154
rs:WP_033600878	DNA topoisomerase III [Enterococcus faecalis].	27.86	402	245	7	47	445	243	602	2e-37	154
rs:WP_016440647	DNA topoisomerase III [Coprococcus sp. HPP0048].	32.85	344	206	12	72	395	299	637	2e-37	154
tr:D4JTZ1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.47	407	250	12	34	425	224	612	2e-37	155
rs:WP_016362159	DNA topoisomerase III [Bacillus cereus].	27.27	429	285	11	35	454	239	649	2e-37	156
tr:A0A059MY33_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.86	402	245	7	47	445	299	658	2e-37	155
rs:WP_008975260	DNA topoisomerase III [Lachnospiraceae bacterium 6_1_37FAA].	32.85	344	206	12	72	395	299	637	2e-37	154
tr:E2ZLR8_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.22	394	247	9	40	425	213	590	2e-37	154
tr:E6HHC9_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.86	402	245	7	47	445	299	658	2e-37	155
rs:WP_033626659	DNA topoisomerase III [Enterococcus faecalis].	27.93	401	246	7	47	445	243	602	2e-37	154
rs:WP_009242248	MULTISPECIES: DNA topoisomerase III [unclassified Lachnospiraceae].	31.18	356	211	10	72	395	299	652	2e-37	154
rs:WP_043715373	hypothetical protein, partial [Symbiobacterium thermophilum].	32.09	349	221	8	40	377	239	582	2e-37	155
rs:WP_006905958	DNA topoisomerase III [Shuttleworthia satelles].	32.64	383	215	13	59	401	349	728	2e-37	155
tr:D4KA47_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.47	407	250	12	34	425	223	611	2e-37	154
rs:WP_004845710	DNA topoisomerase III [[Ruminococcus] torques].	31.18	356	211	10	72	395	299	652	2e-37	154
tr:E6GNJ7_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.85	432	271	8	18	445	268	658	2e-37	155
rs:WP_004842675	DNA topoisomerase III [[Ruminococcus] gnavus].	31.51	365	228	10	72	417	299	660	2e-37	154
rs:WP_010632324	DNA topoisomerase III [Sporolactobacillus vineae].	28.14	398	248	8	36	428	231	595	2e-37	154
rs:WP_024835747	DNA topoisomerase III [Clostridium sp. 12(A)].	29.84	382	226	12	49	392	277	654	2e-37	154
rs:WP_002378482	DNA topoisomerase III [Enterococcus faecalis].	27.86	402	245	7	47	445	243	602	2e-37	154
rs:WP_029468581	DNA topoisomerase III [Clostridiales bacterium VE202-06].	32.17	345	205	11	74	395	301	639	2e-37	154
rs:WP_010496819	DNA topoisomerase III [Lactobacillus acidipiscis].	28.03	396	244	6	41	434	235	591	2e-37	154
rs:WP_014237640	topoisomerase IA [Azospira oryzae].	30.84	428	260	12	19	426	232	643	2e-37	155
rs:WP_042474231	hypothetical protein, partial [Bacillus sp. FF3].	30.12	405	249	9	25	421	230	608	2e-37	154
rs:WP_007860201	hypothetical protein [[Clostridium] citroniae].	31.99	347	221	5	43	385	231	566	2e-37	154
rs:WP_033626788	DNA topoisomerase III [Enterococcus faecalis].	27.86	402	245	7	47	445	243	602	2e-37	154
rs:WP_044954121	DNA topoisomerase III [Faecalibacterium prausnitzii].	31.22	394	247	9	40	425	241	618	2e-37	154
rs:WP_015639657	DNA topoisomerase III [Lactobacillus plantarum].	31.22	378	231	11	33	397	241	602	2e-37	154
rs:WP_010729522	DNA topoisomerase III [Enterococcus faecium].	33.44	314	190	7	57	365	268	567	3e-37	154
rs:WP_043664505	DNA topoisomerase [Clostridium butyricum].	31.26	419	245	14	50	452	263	654	3e-37	154
rs:WP_009899115	DNA topoisomerase [Peptoclostridium difficile].	28.77	438	264	15	29	450	239	644	3e-37	154
rs:WP_034121403	hypothetical protein, partial [Peptococcaceae bacterium BICA1-7].	30.31	353	231	7	47	396	251	591	3e-37	154
rs:WP_006427278	DNA topoisomerase III [Dorea longicatena].	31.48	359	221	11	57	392	287	643	3e-37	154
tr:Q67NT6_SYMTH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.09	349	221	8	40	377	239	582	3e-37	155
rs:WP_033659502	MULTISPECIES: DNA topoisomerase III [Enterococcus].	27.62	391	240	5	47	434	243	593	3e-37	154
rs:WP_008778183	DNA topoisomerase I [Parabacteroides sp. 20_3].	32.53	372	229	11	60	427	263	616	3e-37	154
rs:WP_027634967	DNA topoisomerase [Clostridium butyricum].	31.26	419	245	14	50	452	263	654	3e-37	154
rs:WP_009756925	DNA topoisomerase III [Lachnospiraceae bacterium 2_1_46FAA].	30.09	339	220	8	72	395	301	637	3e-37	154
rs:WP_004308419	MULTISPECIES: DNA topoisomerase I [Bacteroides].	32.53	372	229	11	60	427	263	616	3e-37	154
rs:WP_044942468	DNA topoisomerase III [Flavonifractor plautii].	32.00	350	223	5	40	385	228	566	3e-37	154
rs:WP_010826160	DNA topoisomerase III [Enterococcus faecalis].	27.86	402	245	7	47	445	243	602	3e-37	154
tr:R3KM90_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.97	312	191	6	57	365	269	568	3e-37	154
rs:WP_002417647	DNA topoisomerase III [Enterococcus faecalis].	31.22	362	233	7	40	396	230	580	3e-37	154
rs:WP_010730827	DNA topoisomerase III [Enterococcus faecalis].	27.61	402	246	7	47	445	243	602	3e-37	154
rs:WP_025480081	DNA topoisomerase [Enterococcus faecium].	33.97	312	191	6	57	365	268	567	3e-37	154
tr:S0RWA0_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.23	418	253	10	29	445	195	566	3e-37	154
rs:WP_007749118	DNA topoisomerase I [Bacteroides finegoldii].	32.53	372	229	11	60	427	253	606	3e-37	154
tr:S4FHU0_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.79	433	270	8	18	445	268	658	3e-37	155
rs:WP_008679608	DNA topoisomerase III [Clostridium sp. 7_2_43FAA].	31.20	343	210	11	72	399	300	631	3e-37	154
rs:WP_033660098	DNA topoisomerase III [Enterococcus faecalis].	27.86	402	245	7	47	445	243	602	3e-37	154
rs:WP_005643883	DNA topoisomerase I [Parabacteroides merdae].	32.53	372	229	11	60	427	263	616	3e-37	154
rs:WP_046057802	MULTISPECIES: DNA topoisomerase [Clostridium].	31.26	419	245	14	50	452	263	654	3e-37	154
tr:W2CME8_9PORP	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETK08424.1};	35.02	237	150	4	157	392	21	254	3e-37	147
rs:WP_008780590	DNA topoisomerase I [Bacteroides sp. 3_1_19].	32.53	372	229	11	60	427	263	616	3e-37	154
rs:WP_003428725	DNA topoisomerase [Clostridium butyricum].	31.26	419	245	14	50	452	263	654	3e-37	154
rs:WP_002381707	DNA topoisomerase III [Enterococcus faecalis].	27.62	391	240	5	47	434	243	593	3e-37	154
rs:WP_037995540	DNA topoisomerase III, partial [Tannerella sp. oral taxon BU063].	35.02	237	150	4	157	392	26	259	3e-37	147
tr:S4EN54_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.54	422	265	6	18	434	268	649	3e-37	154
rs:WP_024040672	DNA topoisomerase [Clostridium butyricum].	31.26	419	245	14	50	452	263	654	3e-37	154
rs:WP_022619468	DNA topoisomerase [Peptoclostridium difficile].	28.77	438	264	15	29	450	239	644	3e-37	154
tr:T2NSF2_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.01	411	260	7	40	450	215	585	3e-37	154
rs:WP_027438062	DNA topoisomerase III [Lachnospira multipara].	28.89	405	252	14	43	413	267	669	3e-37	154
rs:WP_034872068	DNA topoisomerase III [Enterococcus faecium].	27.01	411	260	7	40	450	234	604	3e-37	154
rs:WP_008616570	DNA topoisomerase I [Paraprevotella clara].	32.53	372	229	11	60	427	263	616	4e-37	154
tr:S4E1Q5_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.97	312	191	6	57	365	269	568	4e-37	154
rs:WP_019166616	DNA topoisomerase III [Staphylococcus delphini].	28.70	432	273	10	24	449	224	626	4e-37	154
tr:U6S1R1_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.79	433	270	8	18	445	268	658	4e-37	154
rs:WP_025481655	DNA topoisomerase [Enterococcus faecium].	33.97	312	191	6	57	365	268	567	4e-37	154
rs:WP_016084166	DNA topoisomerase III [Bacillus cereus].	27.93	426	286	10	35	454	239	649	4e-37	155
rs:WP_013737914	DNA topoisomerase [Metallosphaera cuprina].	31.95	338	184	9	66	398	256	552	4e-37	154
rs:WP_002579403	DNA topoisomerase III [Clostridium butyricum].	31.26	419	245	14	50	452	263	654	4e-37	154
rs:WP_025480102	DNA topoisomerase [Enterococcus faecium].	33.97	312	191	6	57	365	268	567	4e-37	154
rs:WP_005227252	DNA topoisomerase III [Enterococcus casseliflavus].	27.01	411	260	7	40	450	234	604	4e-37	154
rs:WP_036159633	hypothetical protein, partial [Lysinibacillus odysseyi].	33.04	342	209	8	61	393	252	582	4e-37	154
tr:A0A0B8Q1Z1_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAM73505.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAM73505.1};	37.62	202	118	1	189	390	1	194	4e-37	147
tr:C0QUY8_PERMH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.81	349	191	11	62	396	257	572	4e-37	155
rs:WP_033624327	DNA topoisomerase III [Enterococcus faecalis].	27.86	402	245	7	47	445	243	602	4e-37	154
rs:WP_002325542	DNA topoisomerase III [Enterococcus faecium].	33.97	312	191	6	57	365	269	568	4e-37	154
rs:WP_039930399	DNA topoisomerase III, partial [Anaerostipes sp. 3_2_56FAA].	34.07	273	169	4	24	294	224	487	4e-37	152
tr:R3HW91_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.97	312	191	6	57	365	269	568	4e-37	154
rs:WP_025479250	DNA topoisomerase [Enterococcus faecium].	33.97	312	191	6	57	365	268	567	4e-37	154
rs:WP_046668838	DNA topoisomerase, partial [Enterococcus faecium].	33.65	312	192	6	57	365	232	531	4e-37	154
rs:WP_017768494	hypothetical protein [Streptococcus agalactiae].	29.43	384	237	10	86	455	298	661	4e-37	154
rs:WP_037574799	DNA topoisomerase III [Staphylococcus chromogenes].	27.27	429	283	9	35	457	227	632	4e-37	154
rs:WP_046434613	DNA topoisomerase III [Akkermansia sp. UNK.MGS-1].	30.39	362	220	9	40	385	259	604	4e-37	155
tr:E5VST4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	34.07	273	169	4	24	294	224	487	4e-37	152
tr:W1K7D6_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.23	418	253	10	29	445	211	582	4e-37	153
rs:WP_002370803	DNA topoisomerase III [Enterococcus faecium].	31.22	362	233	7	40	396	230	580	4e-37	154
rs:WP_002349886	DNA topoisomerase, partial [Enterococcus faecium].	33.65	312	192	6	57	365	217	516	4e-37	154
rs:WP_016183792	DNA topoisomerase III [Enterococcus columbae].	26.75	385	248	5	47	431	241	591	4e-37	154
rs:WP_029657351	DNA topoisomerase, partial [Enterococcus faecalis].	33.05	348	213	8	52	392	127	461	4e-37	152
tr:R1VFV3_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.05	348	213	8	52	392	108	442	4e-37	152
rs:WP_005232250	DNA topoisomerase III [Enterococcus casseliflavus].	27.01	411	260	7	40	450	234	604	4e-37	154
rs:WP_044904689	DNA topoisomerase III [[Clostridium] innocuum].	32.75	342	211	8	43	378	213	541	4e-37	153
rs:WP_014112244	DNA topoisomerase III [Oscillibacter valericigenes].	30.91	427	256	13	36	434	256	671	4e-37	154
rs:WP_002485898	DNA topoisomerase III [Staphylococcus epidermidis].	28.91	422	274	10	34	450	226	626	5e-37	154
rs:WP_033119050	DNA topoisomerase III [Intestinimonas butyriciproducens].	31.22	362	233	7	40	396	231	581	5e-37	154
rs:WP_004849107	DNA topoisomerase III [Coprococcus eutactus].	29.74	390	252	13	35	405	258	644	5e-37	154
gp:AM902716_1304	pseudogene [Bordetella petrii]	34.78	253	154	4	202	452	1	244	5e-37	147
rs:WP_033603135	DNA topoisomerase, partial [Enterococcus faecalis].	33.05	348	213	8	52	392	127	461	5e-37	152
rs:WP_032812369	DNA topoisomerase I [Bacteroides xylanisolvens].	32.53	372	229	11	60	427	263	616	5e-37	154
rs:WP_021912630	DNA topoisomerase [Eubacterium sp. CAG:786].	29.59	392	241	11	56	428	244	619	5e-37	153
rs:WP_034865743	DNA topoisomerase III [Enterococcus durans].	28.23	418	253	10	29	445	229	600	5e-37	153
rs:WP_045660704	DNA topoisomerase [Clostridiaceae bacterium BRH_c20a].	30.53	393	242	12	30	406	263	640	5e-37	153
rs:WP_010825356	DNA topoisomerase III [Enterococcus faecalis].	27.61	402	246	7	47	445	243	602	5e-37	153
rs:WP_044782902	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	31.32	364	226	9	65	425	269	611	5e-37	153
tr:A0A099I8C9_CLOIN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	32.75	342	211	8	43	378	219	547	5e-37	153
rs:WP_016208465	DNA topoisomerase III [Clostridium sartagoforme].	30.06	356	223	11	59	399	287	631	5e-37	153
rs:WP_016324269	DNA topoisomerase III [Oscillibacter sp. 1-3].	29.34	426	285	8	27	449	218	630	5e-37	154
rs:WP_032078168	DNA topoisomerase III [Clostridium drakei].	30.73	358	225	9	57	399	292	641	5e-37	154
rs:WP_002584963	MULTISPECIES: DNA topoisomerase III [Clostridiales].	32.75	342	211	8	43	378	231	559	5e-37	153
rs:WP_010817457	DNA topoisomerase III [Enterococcus faecalis].	27.61	402	246	7	47	445	243	602	5e-37	153
rs:WP_009272259	DNA topoisomerase III [Erysipelotrichaceae bacterium 3_1_53].	30.43	391	240	11	74	450	280	652	5e-37	154
rs:WP_022059536	DNA topoisomerase [Coprococcus eutactus CAG:665].	29.74	390	252	13	35	405	258	644	5e-37	153
rs:WP_009218495	DNA topoisomerase III [Lachnospiraceae oral taxon 107].	29.91	351	228	8	56	392	285	631	6e-37	153
rs:WP_042959782	DNA topoisomerase [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	6e-37	154
rs:WP_044145861	DNA topoisomerase, partial [Enterococcus faecium].	33.65	312	192	6	57	365	51	350	6e-37	152
rs:WP_047000790	DNA topoisomerase III [Clostridium beijerinckii].	30.06	356	223	11	59	399	287	631	6e-37	153
tr:S4BBF3_ENTCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.01	411	260	7	40	450	215	585	6e-37	153
rs:WP_002498569	DNA topoisomerase III [Staphylococcus epidermidis].	28.64	426	270	10	34	450	226	626	6e-37	153
rs:WP_016147854	DNA topoisomerase III [Butyricicoccus pullicaecorum].	29.26	417	254	15	40	444	228	615	6e-37	153
rs:WP_035109339	DNA topoisomerase [Clostridium tetani].	31.32	431	249	17	40	452	253	654	6e-37	154
rs:WP_017867276	DNA topoisomerase III [Lactobacillus pobuzihii].	27.66	394	244	6	43	434	237	591	6e-37	153
tr:S5W9T8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.65	312	192	6	57	365	269	568	6e-37	154
rs:WP_025654210	DNA topoisomerase III [Clostridiales bacterium VE202-21].	30.92	414	251	10	47	440	235	633	6e-37	153
rs:WP_002474079	DNA topoisomerase III [Staphylococcus epidermidis].	28.64	426	270	10	34	450	226	626	6e-37	153
rs:WP_002305772	DNA topoisomerase [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	6e-37	154
tr:Q893I6_CLOTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.32	431	249	17	40	452	255	656	6e-37	153
rs:WP_034552094	DNA topoisomerase III [Carnobacterium funditum].	28.12	409	263	11	58	454	263	652	6e-37	153
rs:WP_035140704	DNA topoisomerase [Clostridium tetani].	31.16	430	251	16	40	452	253	654	6e-37	153
rs:WP_015498061	DNA recombination protein RmuC [Octadecabacter antarcticus].	32.30	356	215	9	38	377	232	577	6e-37	153
rs:WP_002360012	DNA topoisomerase III [Enterococcus faecalis].	27.61	402	246	7	47	445	243	602	6e-37	153
rs:WP_006774454	DNA topoisomerase III [Hungatella hathewayi].	31.71	350	224	5	40	385	228	566	6e-37	153
rs:WP_035125039	DNA topoisomerase [Clostridium tetani].	31.32	431	249	17	40	452	253	654	7e-37	153
rs:WP_002169636	DNA topoisomerase I [Bacillus cereus].	27.19	423	287	10	38	454	242	649	7e-37	155
rs:WP_003414269	DNA topoisomerase [Clostridium butyricum].	31.26	419	245	14	50	452	263	654	7e-37	153
tr:D6DKQ5_CLOSC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.71	350	224	5	40	385	228	566	7e-37	153
rs:WP_026726938	DNA topoisomerase I [Flavobacterium denitrificans].	30.14	345	230	5	48	391	250	584	7e-37	153
tr:G5GKY2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.88	368	218	12	37	398	242	586	7e-37	152
rs:WP_025481001	DNA topoisomerase [Enterococcus faecium].	33.44	314	190	7	57	365	268	567	7e-37	153
rs:WP_017794555	hypothetical protein [Streptococcus iniae].	28.83	385	237	13	86	455	298	660	7e-37	153
rs:WP_033698227	DNA topoisomerase I [Bacillus thuringiensis].	27.36	424	291	9	35	454	239	649	7e-37	154
rs:WP_029699126	DNA topoisomerase III [Clostridium sp. Ade.TY].	30.46	348	214	11	65	396	293	628	7e-37	152
rs:WP_008753349	DNA topoisomerase III [Lachnoanaerobaculum saburreum].	30.79	354	229	9	51	392	280	629	7e-37	153
tr:S4BMI7_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.56	433	271	8	18	445	268	658	7e-37	154
rs:WP_023438760	DNA topoisomerase I [Clostridium tetani].	31.97	416	238	16	54	452	267	654	7e-37	153
rs:WP_033598758	DNA topoisomerase III [Enterococcus faecalis].	27.93	401	246	7	47	445	243	602	7e-37	153
rs:WP_034857843	DNA topoisomerase III [Enterococcus casseliflavus].	27.01	411	260	7	40	450	234	604	8e-37	153
rs:WP_033612972	DNA topoisomerase, partial [Enterococcus faecium].	33.05	348	213	8	52	392	264	598	8e-37	152
rs:WP_033628392	DNA topoisomerase, partial [Enterococcus faecalis].	34.30	309	183	7	52	354	40	334	8e-37	148
rs:WP_024564950	DNA topoisomerase [Elizabethkingia anophelis].	29.31	389	243	12	65	446	255	618	8e-37	152
rs:WP_040427949	DNA topoisomerase III, partial [Acetivibrio cellulolyticus].	32.97	276	170	6	38	309	236	500	8e-37	151
rs:WP_005935499	DNA topoisomerase III [Faecalibacterium prausnitzii].	31.12	376	236	9	36	396	227	594	8e-37	153
rs:WP_015497327	DNA recombination protein RmuC [Octadecabacter arcticus].	32.29	353	219	9	38	377	232	577	8e-37	153
rs:WP_035635729	DNA topoisomerase III [Lachnospiraceae bacterium ND2006].	31.20	359	223	8	59	396	285	640	8e-37	152
rs:WP_024727418	hypothetical protein [Clostridiales bacterium VE202-09].	29.58	409	249	14	50	446	278	659	9e-37	153
rs:WP_047034075	DNA topoisomerase I [Elizabethkingia meningoseptica].	30.61	330	218	5	48	376	250	569	9e-37	153
rs:WP_002470665	DNA topoisomerase III [Staphylococcus epidermidis].	28.91	422	274	10	34	450	226	626	9e-37	153
rs:WP_036609206	DNA topoisomerase III [Oribacterium sp. P6A1].	32.16	370	218	15	61	401	294	659	9e-37	152
rs:WP_000352443	DNA topoisomerase I, partial [Bacillus thuringiensis].	27.34	428	286	11	35	454	27	437	9e-37	152
rs:WP_010784036	DNA topoisomerase III [Enterococcus faecalis].	26.62	432	272	8	18	445	212	602	9e-37	152
tr:C3HSH8_BACTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.34	428	286	11	35	454	1	411	9e-37	152
rs:WP_040883102	DNA topoisomerase [Johnsonella ignava].	32.88	368	218	12	37	398	222	566	9e-37	152
rs:WP_047956874	DNA topoisomerase III, partial [Bacillus anthracis].	28.78	410	264	11	57	448	77	476	9e-37	152
tr:E0GRL9_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.56	433	271	8	18	445	268	658	9e-37	153
rs:WP_048310837	DNA topoisomerase III [Anaerobacillus macyae].	28.54	438	261	13	36	450	241	649	1e-36	153
rs:WP_022375749	DNA topoisomerase III [Firmicutes bacterium CAG:270].	30.55	347	223	11	69	401	297	639	1e-36	152
rs:WP_044155318	DNA topoisomerase I, partial [Bacteroides intestinalis].	32.93	328	200	8	60	384	154	464	1e-36	152
rs:WP_044912868	DNA topoisomerase III [Butyrivibrio sp. WCE2006].	30.14	418	249	14	22	400	245	658	1e-36	152
rs:WP_002341526	DNA topoisomerase III [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	1e-36	152
gp:CP009300_2741	DNA topoisomerase III family protein [Bacillus cereus D17]	32.76	290	179	7	36	321	244	521	1e-36	151
rs:WP_018596389	DNA topoisomerase III [Blautia producta].	31.88	345	206	11	74	395	301	639	1e-36	152
rs:WP_027415690	DNA topoisomerase [Aneurinibacillus terranovensis].	28.34	427	270	11	36	450	248	650	1e-36	153
tr:K1RSX6_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC46549.1}; Flags: Fragment;	31.79	390	213	13	79	445	17	376	1e-36	150
rs:WP_009262078	DNA topoisomerase III [Coprococcus sp. HPP0074].	32.56	344	207	12	72	395	299	637	1e-36	152
rs:WP_039428003	DNA topoisomerase I [Porphyromonas sp. COT-052 OH4946].	29.09	385	253	9	47	427	248	616	1e-36	152
rs:WP_038809474	DNA topoisomerase [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	1e-36	153
tr:I4V807_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.11	371	229	9	77	445	272	610	1e-36	152
rs:WP_022230671	DNA topoisomerase [Firmicutes bacterium CAG:41].	29.59	419	260	13	40	450	228	619	1e-36	152
rs:WP_028778686	hypothetical protein [Shimazuella kribbensis].	26.68	431	287	13	32	452	232	643	1e-36	152
rs:WP_027098238	MULTISPECIES: DNA topoisomerase [Clostridium].	29.53	430	258	14	40	452	253	654	1e-36	152
rs:WP_024807736	topoisomerase I [Verrucomicrobia bacterium LP2A].	29.87	375	234	8	24	385	243	601	1e-36	154
rs:WP_008376150	DNA topoisomerase III [Enterococcus sp. C1].	27.01	411	260	7	40	450	234	604	1e-36	152
rs:WP_042513583	DNA topoisomerase III, partial [Bacillus cereus].	32.76	290	179	7	36	321	244	521	1e-36	151
rs:WP_025487227	DNA topoisomerase III [Clostridiales bacterium VE202-28].	29.11	395	233	12	43	392	272	664	1e-36	152
rs:WP_039956461	DNA topoisomerase III [Bacillus sp. M 2-6].	29.11	371	229	9	77	445	274	612	1e-36	152
rs:WP_013385940	DNA topoisomerase III [Paenibacillus polymyxa].	26.17	428	280	10	36	449	230	635	1e-36	153
rs:WP_026885431	DNA topoisomerase [Clostridium beijerinckii].	30.80	448	259	18	27	452	237	655	1e-36	152
rs:WP_010729361	DNA topoisomerase III [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	1e-36	152
rs:WP_045716702	DNA topoisomerase III, partial [Salmonella enterica].	40.66	182	106	2	36	217	251	430	1e-36	150
rs:WP_004367385	DNA topoisomerase TopB, partial [Prevotella nigrescens].	30.90	356	219	10	74	425	160	492	1e-36	151
rs:WP_032708797	DNA topoisomerase, partial [Pseudomonas syringae].	30.29	416	251	12	36	428	254	653	1e-36	154
rs:WP_034727120	DNA topoisomerase I [Chryseobacterium sp. JM1].	29.86	345	231	5	48	391	250	584	1e-36	152
tr:K1RRE4_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC46094.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EKC46094.1};	30.33	399	244	13	62	445	246	625	1e-36	152
rs:WP_008716160	DNA topoisomerase III [Clostridiales bacterium 1_7_47FAA].	29.11	395	233	12	43	392	272	664	1e-36	152
tr:W1WUK7_9ZZZZ	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:ETJ21606.1}; Flags: Fragment;	28.91	422	274	10	34	450	182	582	1e-36	152
rs:WP_005877022	DNA topoisomerase III [Enterococcus durans].	33.33	312	193	6	57	365	268	567	1e-36	152
rs:WP_000280352	hypothetical protein [Bacillus cereus].	27.45	470	306	12	4	448	219	678	1e-36	153
rs:WP_005832597	DNA topoisomerase I [Bacteroides uniformis].	34.07	317	189	8	71	384	278	577	1e-36	152
rs:WP_037571267	DNA topoisomerase III [Staphylococcus aureus].	27.32	410	270	9	47	450	239	626	1e-36	152
rs:WP_027116342	DNA topoisomerase III [Lachnospiraceae bacterium P6B14].	30.00	390	230	11	56	405	340	726	1e-36	153
tr:A8RRB2_CLOBW	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.57	399	233	13	43	392	276	671	1e-36	152
rs:WP_000186172	DNA topoisomerase III [Bacillus cereus].	27.44	430	275	14	46	454	253	666	1e-36	152
rs:WP_047927463	DNA topoisomerase [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	1e-36	152
sp:TOP3_STAHJ	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	27.32	410	270	9	47	450	239	626	1e-36	152
rs:WP_016181416	DNA topoisomerase III [Enterococcus avium].	26.41	409	260	7	41	449	235	602	1e-36	152
rs:WP_047982994	DNA topoisomerase [Ornithinibacillus californiensis].	27.66	441	280	12	24	450	236	651	1e-36	152
rs:WP_012974496	DNA topoisomerase III [Azospirillum lipoferum].	31.44	353	205	11	67	385	258	607	2e-36	153
tr:B3CB28_9BACE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EDV04280.1};	32.93	328	200	8	60	384	189	499	2e-36	151
rs:WP_039890715	DNA topoisomerase III [Hungatella hathewayi].	30.70	355	233	6	47	397	231	576	2e-36	152
rs:WP_025477734	DNA topoisomerase [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	2e-36	152
rs:WP_002564358	MULTISPECIES: DNA topoisomerase III [Lachnoclostridium].	28.57	399	233	13	43	392	272	667	2e-36	152
rs:WP_002295634	DNA topoisomerase [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	2e-36	152
rs:WP_026891460	DNA topoisomerase III [[Clostridium] aerotolerans].	29.30	372	221	11	59	392	287	654	2e-36	152
rs:WP_025481008	DNA topoisomerase [Enterococcus faecium].	33.12	314	191	7	57	365	268	567	2e-36	152
rs:WP_016171207	DNA topoisomerase III [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	2e-36	152
rs:WP_025479564	DNA topoisomerase [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	2e-36	152
rs:WP_037558586	DNA topoisomerase III [Staphylococcus haemolyticus].	27.32	410	270	9	47	450	239	626	2e-36	152
tr:D3ABL1_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	30.70	355	233	6	47	397	231	576	2e-36	152
rs:WP_015617751	topoisomerase IA [Clostridium pasteurianum].	29.21	428	256	14	43	452	256	654	2e-36	152
rs:WP_002331358	DNA topoisomerase III [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	2e-36	152
rs:WP_000520757	DNA topoisomerase I [Bacillus cereus].	25.06	431	307	8	33	459	237	655	2e-36	153
rs:WP_010726014	DNA topoisomerase III [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	2e-36	152
rs:WP_002354426	DNA topoisomerase [Enterococcus faecium].	33.33	315	195	6	54	365	265	567	2e-36	152
rs:WP_025657742	DNA topoisomerase III [Clostridiales bacterium VE202-21].	31.61	386	222	13	47	392	271	654	2e-36	152
rs:WP_002335350	DNA topoisomerase III [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	2e-36	152
rs:WP_047936608	DNA topoisomerase [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	2e-36	152
rs:WP_040446585	DNA topoisomerase III [Eubacterium ventriosum].	29.80	396	248	12	61	445	249	625	2e-36	152
tr:D4QPS7_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.65	312	192	6	57	365	269	568	2e-36	152
rs:WP_000542405	topoisomerase III [Bacillus cereus].	28.34	441	273	15	35	454	247	665	2e-36	152
rs:WP_002486256	DNA topoisomerase III [Staphylococcus epidermidis].	28.71	425	269	10	35	450	227	626	2e-36	152
rs:WP_019975895	DNA topoisomerase [Empedobacter brevis].	29.81	369	237	7	24	391	237	584	2e-36	152
rs:WP_025478641	DNA topoisomerase [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	2e-36	152
rs:WP_034867809	DNA topoisomerase I [Elizabethkingia miricola].	30.08	369	236	7	24	391	237	584	2e-36	152
rs:WP_037536003	DNA topoisomerase III [Staphylococcus haemolyticus].	27.64	398	260	9	59	450	251	626	2e-36	152
rs:WP_025477548	DNA topoisomerase [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	2e-36	152
rs:WP_009510834	DNA topoisomerase [Opitutaceae bacterium TAV5].	28.90	429	264	9	39	446	238	646	2e-36	153
rs:WP_004039093	DNA topoisomerase III [Clostridium sp. ASF356].	28.33	406	258	12	56	452	244	625	2e-36	152
rs:WP_012062393	DNA topoisomerase III [Alkaliphilus metalliredigens].	29.69	421	245	17	72	452	301	710	2e-36	152
tr:R9IKQ1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.48	420	251	9	40	445	97	489	2e-36	151
rs:WP_025477545	DNA topoisomerase [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	2e-36	152
rs:WP_047937327	DNA topoisomerase [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	2e-36	152
rs:WP_014613208	DNA topoisomerase III [Staphylococcus pseudintermedius].	28.80	434	270	12	24	449	224	626	2e-36	152
rs:WP_025480863	DNA topoisomerase [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	2e-36	152
rs:WP_016853417	DNA topoisomerase [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	2e-36	152
sp:TOP3_STAES	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	28.91	422	274	10	34	450	226	626	2e-36	152
rs:WP_025020293	DNA topoisomerase III [Lactobacillus equi].	28.43	394	233	9	47	434	242	592	2e-36	152
rs:WP_007362128	DNA topoisomerase [Opitutaceae bacterium TAV1].	29.22	438	268	10	39	454	238	655	2e-36	153
tr:A5Z4Y4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.80	396	248	12	61	445	237	613	2e-36	152
rs:WP_012008596	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	24.59	431	309	8	33	459	237	655	2e-36	153
rs:WP_008751237	DNA topoisomerase III [Lachnoanaerobaculum saburreum].	31.09	357	224	9	51	392	280	629	2e-36	151
rs:WP_037542431	DNA topoisomerase III [Staphylococcus pseudintermedius].	28.80	434	270	12	24	449	224	626	2e-36	152
rs:WP_039883879	DNA topoisomerase III, partial [Achromobacter piechaudii].	37.90	219	130	2	190	406	1	215	2e-36	144
rs:WP_000520758	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	24.83	431	308	8	33	459	237	655	2e-36	153
rs:WP_034229263	hypothetical protein, partial [Lachnospiraceae bacterium 3-1].	30.48	420	251	9	40	445	128	520	2e-36	151
tr:A0A078RFF4_BACVU	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:KDS33481.1};	30.60	366	236	9	60	421	250	601	2e-36	151
rs:WP_039328218	DNA topoisomerase I [Myroides sp. A21].	31.86	317	202	7	70	384	272	576	2e-36	151
rs:WP_008432102	DNA topoisomerase III [Planococcus donghaensis].	29.27	410	252	15	59	454	266	651	2e-36	152
tr:C3DWP7_BACTS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.83	431	308	8	33	459	237	655	2e-36	153
rs:WP_010737146	MULTISPECIES: DNA topoisomerase III, partial [Enterococcus].	28.61	402	242	9	47	445	207	566	2e-36	151
rs:WP_000520729	DNA topoisomerase I [Bacillus cereus].	27.36	424	291	9	35	454	239	649	2e-36	153
rs:WP_002494147	DNA topoisomerase III [Staphylococcus epidermidis].	28.64	426	270	10	34	450	226	626	2e-36	152
rs:WP_045171904	DNA topoisomerase [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	2e-36	152
rs:WP_002477639	DNA topoisomerase 3 [Staphylococcus epidermidis].	28.64	426	270	10	34	450	226	626	2e-36	152
rs:WP_000520730	DNA topoisomerase I [Bacillus thuringiensis].	27.36	424	291	9	35	454	239	649	2e-36	153
tr:D4K2M3_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.19	424	255	13	34	445	211	605	2e-36	151
rs:WP_034700637	DNA topoisomerase III [Enterococcus hirae].	28.61	402	242	9	47	445	207	566	2e-36	151
rs:WP_026510388	DNA topoisomerase III [Butyrivibrio sp. LC3010].	30.14	418	249	14	22	400	245	658	2e-36	151
rs:WP_036835670	DNA topoisomerase III [Pontibacillus litoralis].	31.96	341	207	8	66	404	264	581	2e-36	151
tr:U2JQH5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.25	400	251	10	53	445	241	619	3e-36	151
rs:WP_009064311	DNA topoisomerase III [Clostridium sp. MSTE9].	32.97	367	222	9	34	394	221	569	3e-36	151
rs:WP_022215638	DNA topoisomerase [Blautia sp. CAG:237].	31.55	374	222	14	57	400	53	422	3e-36	149
tr:W7YS18_9BACT	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:GAF05224.1};	32.76	290	184	7	27	316	220	498	3e-36	150
rs:WP_019167893	DNA topoisomerase III [Staphylococcus intermedius].	28.47	418	271	9	38	449	231	626	3e-36	151
tr:T4JS35_PEPDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.33	312	193	6	57	365	268	567	3e-36	152
rs:WP_000520734	DNA topoisomerase I [Bacillus cereus].	27.36	424	291	9	35	454	239	649	3e-36	153
rs:WP_010720799	DNA topoisomerase III, partial [Enterococcus hirae].	28.61	402	242	9	47	445	207	566	3e-36	151
rs:WP_036740468	DNA topoisomerase III, partial [Peptostreptococcaceae bacterium oral taxon 113].	30.25	400	251	10	53	445	241	619	3e-36	151
rs:WP_002299813	DNA topoisomerase [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	3e-36	152
rs:WP_020531862	hypothetical protein [Flexithrix dorotheae].	31.06	396	245	11	40	427	234	609	3e-36	152
rs:WP_025479791	DNA topoisomerase [Enterococcus faecium].	33.33	315	195	6	54	365	265	567	3e-36	152
rs:WP_033059191	MULTISPECIES: DNA topoisomerase III [Clostridium].	30.08	369	229	10	40	398	252	601	3e-36	150
rs:WP_026660106	DNA topoisomerase III [Butyrivibrio sp. AC2005].	31.02	403	237	13	35	400	259	657	3e-36	151
tr:D3LJR4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.65	312	192	6	57	365	269	568	3e-36	152
tr:D8HAD9_BACAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.12	424	292	9	35	454	222	632	3e-36	153
rs:WP_021894879	DNA topoisomerase [Clostridium bolteae CAG:59].	28.57	399	233	12	43	392	272	667	3e-36	151
rs:WP_032944513	DNA topoisomerase I [Bacteroides vulgatus].	30.60	366	236	9	60	421	262	613	3e-36	151
tr:E4IYX6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.33	312	193	6	57	365	269	568	3e-36	152
rs:WP_010726512	DNA topoisomerase III [Enterococcus faecium].	33.33	315	195	6	54	365	265	567	3e-36	152
rs:WP_002321299	DNA topoisomerase [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	3e-36	152
tr:J6U692_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.33	312	193	6	57	365	92	391	3e-36	150
rs:WP_002574756	DNA topoisomerase III [[Clostridium] bolteae].	28.57	399	233	13	43	392	272	667	3e-36	151
rs:WP_020152122	hypothetical protein [Verrucomicrobia bacterium SCGC AAA300-N18].	30.19	361	229	7	47	398	261	607	3e-36	152
rs:WP_045582666	DNA topoisomerase III [Azospirillum thiophilum].	31.48	359	200	11	67	385	258	610	3e-36	152
rs:WP_022097691	DNA topoisomerase [Eubacterium eligens CAG:72].	30.00	360	224	11	59	392	303	660	3e-36	151
rs:WP_003525508	DNA topoisomerase III [[Clostridium] clostridioforme].	29.78	356	239	5	40	393	230	576	3e-36	151
rs:WP_025478649	DNA topoisomerase [Enterococcus faecium].	33.33	315	195	6	54	365	265	567	3e-36	152
rs:WP_002318121	DNA topoisomerase [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	3e-36	152
rs:WP_014748829	DNA topoisomerase [Enterococcus faecium].	33.02	315	196	6	54	365	265	567	3e-36	150
rs:WP_044051694	DNA topoisomerase, partial [Enterococcus faecium].	33.02	315	196	6	54	365	265	567	3e-36	150
rs:WP_032586616	DNA topoisomerase I [Bacteroides fragilis].	32.85	344	220	9	43	384	246	580	3e-36	151
rs:WP_000520728	DNA topoisomerase I [Bacillus cereus].	27.12	424	292	9	35	454	239	649	3e-36	152
rs:WP_022278616	DNA topoisomerase III [Dorea sp. AGR2135].	30.93	388	214	12	57	392	282	667	3e-36	151
rs:WP_037549759	DNA topoisomerase III [Staphylococcus haemolyticus].	27.39	398	261	9	59	450	251	626	3e-36	151
rs:WP_010700012	DNA topoisomerase [Acinetobacter radioresistens].	29.56	433	262	13	29	432	262	680	3e-36	153
rs:WP_003360737	DNA topoisomerase III [Clostridium botulinum].	30.35	369	228	10	40	398	252	601	3e-36	150
rs:WP_022416141	DNA topoisomerase [Dorea longicatena CAG:42].	29.87	385	230	12	40	392	72	448	3e-36	149
rs:WP_002314426	DNA topoisomerase [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	3e-36	151
rs:WP_033592006	DNA topoisomerase III [Enterococcus faecalis].	26.33	433	272	8	18	445	212	602	3e-36	151
tr:A0A0D5MB95_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.36	343	214	8	57	392	268	599	3e-36	151
rs:WP_033692010	DNA topoisomerase I [Bacillus cereus].	27.12	424	292	9	35	454	239	649	3e-36	152
rs:WP_010731512	DNA topoisomerase III [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	3e-36	151
rs:WP_005336206	DNA topoisomerase III [Dorea formicigenerans].	30.93	388	214	12	57	392	282	667	3e-36	151
rs:WP_023523820	DNA topoisomerase III [Enterococcus mundtii].	33.33	315	195	6	54	365	265	567	3e-36	151
rs:WP_032887862	DNA topoisomerase [Fusobacterium nucleatum].	32.92	319	200	6	74	382	269	583	3e-36	150
rs:WP_047655115	DNA topoisomerase [Enterococcus faecium].	32.17	314	194	7	57	365	268	567	4e-36	150
tr:R4BEW2_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOM38169.1};	31.39	360	206	14	110	454	1	334	4e-36	148
rs:WP_019842535	hypothetical protein [Escherichia coli].	27.74	429	268	7	31	440	256	661	4e-36	151
rs:WP_047383600	hypothetical protein, partial [Cetobacterium sp. ZWU0022].	32.05	312	194	6	65	365	8	312	4e-36	146
tr:L8A4L4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.65	312	192	6	57	365	269	568	4e-36	151
rs:WP_025480603	DNA topoisomerase [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	4e-36	151
rs:WP_040578486	DNA topoisomerase, partial [Methylomicrobium album].	29.13	412	264	10	37	446	231	616	4e-36	150
rs:WP_025479080	DNA topoisomerase [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	4e-36	151
rs:WP_002338048	DNA topoisomerase III, partial [Enterococcus faecium].	31.79	346	218	8	54	392	242	576	4e-36	151
rs:WP_002307526	DNA topoisomerase [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	4e-36	151
rs:WP_022319653	DNA topoisomerase [Dorea sp. CAG:317].	30.28	360	234	11	47	392	271	627	4e-36	150
rs:WP_014125497	DNA topoisomerase III [Tetragenococcus halophilus].	26.57	399	254	8	47	445	241	600	4e-36	151
rs:WP_024634928	MULTISPECIES: DNA topoisomerase [Enterococcus].	33.65	312	192	6	57	365	268	567	4e-36	151
rs:WP_016225184	DNA topoisomerase III [Lachnospiraceae bacterium 3-2].	29.84	372	221	9	59	392	286	655	4e-36	151
rs:WP_016357804	DNA topoisomerase I TopA [Methanobrevibacter sp. AbM4].	28.17	458	263	13	18	458	220	628	4e-36	151
rs:WP_016628767	DNA topoisomerase [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	4e-36	151
rs:WP_010721414	DNA topoisomerase III [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	4e-36	151
rs:WP_021885775	DNA topoisomerase [Clostridium sp. CAG:590].	28.64	419	245	11	40	439	139	522	4e-36	150
rs:WP_040682411	MULTISPECIES: DNA topoisomerase I, partial [Methanobrevibacter].	28.17	458	263	13	18	458	220	628	4e-36	151
rs:WP_025531786	DNA topoisomerase III [Hungatella hathewayi].	29.70	404	240	13	35	397	260	660	4e-36	150
rs:WP_006566846	DNA topoisomerase III [Anaerostipes caccae].	29.65	371	241	10	47	400	277	644	4e-36	150
tr:H8GM49_METAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.13	412	264	10	37	446	231	616	4e-36	150
tr:L2LKT7_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.65	312	192	6	57	365	269	568	4e-36	151
rs:WP_033613525	DNA topoisomerase, partial [Enterococcus faecium].	33.98	309	184	7	52	354	40	334	4e-36	147
rs:WP_047937797	DNA topoisomerase [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	4e-36	151
sp:TOP3_STAEQ	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	28.91	422	274	10	34	450	226	626	4e-36	151
tr:E1YRP3_9PORP	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFK63720.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFK63720.1};	31.83	377	223	11	60	430	39	387	4e-36	149
rs:WP_044144889	DNA topoisomerase [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	4e-36	151
rs:WP_045756432	DNA topoisomerase I [Sphingobacterium sp. PM2-P1-29].	30.86	337	222	5	56	391	259	585	4e-36	150
rs:WP_034061700	hypothetical protein [Pseudomonas aeruginosa].	27.77	443	273	13	36	449	240	664	4e-36	151
rs:WP_035628096	DNA topoisomerase III [Lachnospiraceae bacterium C6A11].	31.32	364	204	13	72	393	299	658	4e-36	150
rs:WP_006829051	DNA topoisomerase III [Planococcus antarcticus].	29.23	414	251	16	57	454	264	651	4e-36	150
rs:WP_044153114	hypothetical protein [Salinibacillus aidingensis].	26.26	438	295	8	38	454	249	679	4e-36	151
rs:WP_008153388	hypothetical protein, partial [Parabacteroides johnsonii].	31.83	377	223	11	60	430	100	448	4e-36	149
rs:WP_010724793	hypothetical protein, partial [Enterococcus faecium].	33.98	309	184	7	52	354	45	339	4e-36	147
rs:WP_030034759	DNA topoisomerase III [Clostridium botulinum].	30.35	369	228	10	40	398	252	601	5e-36	150
rs:WP_047394771	hypothetical protein [Cetobacterium sp. ZOR0034].	28.99	407	263	13	65	457	311	705	5e-36	151
rs:WP_033125583	DNA topoisomerase III [Eubacterium sp. ER2].	29.63	378	234	10	46	393	289	664	5e-36	150
rs:WP_047342146	DNA topoisomerase III [Enterococcus cecorum].	26.36	387	245	6	47	431	241	589	5e-36	150
rs:WP_022300463	DNA topoisomerase III [Erysipelotrichaceae bacterium CAG:64].	28.37	430	276	11	35	450	153	564	5e-36	150
rs:WP_045754349	DNA topoisomerase I [Sphingobacterium sp. PM2-P1-29].	31.90	348	220	8	48	391	250	584	5e-36	150
rs:WP_036304041	DNA topoisomerase [Methylomicrobium agile].	29.61	412	262	11	37	446	231	616	5e-36	150
rs:WP_040893084	DNA topoisomerase III [[Bacteroides] pectinophilus].	28.46	397	232	12	56	413	303	686	5e-36	150
rs:WP_046151725	DNA topoisomerase I [Parabacteroides sp. HGS0025].	29.67	391	256	10	40	427	241	615	5e-36	150
rs:WP_022361881	DNA topoisomerase [Bacteroides pectinophilus CAG:437].	28.46	397	232	12	56	413	303	686	5e-36	150
rs:WP_002604273	DNA topoisomerase III [Hungatella hathewayi].	29.70	404	240	13	35	397	260	660	5e-36	150
rs:WP_002348823	DNA topoisomerase, partial [Enterococcus faecium].	33.33	312	193	6	57	365	129	428	5e-36	149
tr:S4G1Y5_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.33	433	272	8	18	445	268	658	5e-36	151
rs:WP_004634442	DNA topoisomerase III [Gemella morbillorum].	33.61	363	214	11	37	396	225	563	5e-36	149
rs:WP_002316073	DNA topoisomerase [Enterococcus faecium].	33.33	315	195	6	54	365	265	567	5e-36	151
rs:WP_002338047	DNA topoisomerase III, partial [Enterococcus faecium].	33.33	315	195	6	54	365	265	567	5e-36	150
rs:WP_022223423	DNA topoisomerase III [Clostridium sp. CAG:253].	30.64	359	217	11	72	401	302	657	5e-36	150
rs:WP_035642014	DNA topoisomerase III [Lachnospiraceae bacterium FE2018].	29.29	379	223	10	57	392	318	694	5e-36	151
rs:WP_014733804	DNA topoisomerase I [Pyrococcus sp. ST04].	30.79	445	243	17	40	457	245	651	5e-36	150
rs:WP_013056649	DNA topoisomerase [Bacillus megaterium].	30.41	411	241	14	57	450	269	651	5e-36	150
rs:WP_042346581	DNA topoisomerase [Bacillus sp. G2(2012b)].	30.28	426	254	15	38	450	252	647	5e-36	151
rs:WP_002369673	DNA topoisomerase [Enterococcus faecium].	32.17	314	194	7	57	365	268	567	5e-36	151
tr:B7ATA4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.46	397	232	12	56	413	307	690	5e-36	150
rs:WP_032566798	DNA topoisomerase I, partial [Bacteroides fragilis].	32.10	377	222	10	60	430	117	465	5e-36	149
rs:WP_029493414	DNA topoisomerase III [Fusobacterium hwasookii].	32.92	319	200	6	74	382	269	583	5e-36	150
rs:WP_029567330	DNA topoisomerase III [Bacillus cibi].	26.90	420	282	10	44	454	254	657	5e-36	150
tr:D4RK56_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.12	314	191	7	57	365	269	568	5e-36	151
rs:WP_010731122	DNA topoisomerase III [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	5e-36	151
rs:WP_018711724	DNA topoisomerase I [Bacteroides barnesiae].	32.36	377	221	10	60	430	263	611	6e-36	150
rs:WP_026835960	DNA topoisomerase III [Eubacterium xylanophilum].	29.80	406	255	13	22	401	247	648	6e-36	150
rs:WP_029675922	DNA topoisomerase, partial [Enterococcus faecalis].	34.21	304	176	9	98	392	1	289	6e-36	145
rs:WP_002489667	DNA topoisomerase 3 [Staphylococcus epidermidis].	28.91	422	274	10	34	450	226	626	6e-36	150
rs:WP_021680133	DNA topoisomerase [Porphyromonas gingivalis].	28.83	385	254	9	47	427	248	616	6e-36	150
rs:WP_002326882	DNA topoisomerase III [Enterococcus faecium].	33.12	314	191	7	57	365	268	567	6e-36	150
rs:WP_033704841	DNA topoisomerase [Enterococcus faecium].	33.12	314	191	7	57	365	268	567	6e-36	150
rs:WP_002320569	DNA topoisomerase [Enterococcus faecium].	33.33	315	195	6	54	365	265	567	6e-36	150
rs:WP_029283791	DNA topoisomerase III [Bacillus indicus].	26.90	420	282	10	44	454	254	657	6e-36	150
rs:WP_002489011	DNA topoisomerase III [Staphylococcus epidermidis].	28.67	422	275	10	34	450	226	626	6e-36	150
rs:WP_021904993	DNA topoisomerase III [Clostridium sp. CAG:81].	29.40	432	239	13	3	392	248	655	6e-36	150
rs:WP_031908286	DNA topoisomerase III, partial [Staphylococcus aureus].	28.04	378	251	9	59	427	255	620	6e-36	150
rs:WP_024300313	DNA topoisomerase [Methylosarcina lacus].	30.24	410	257	11	39	446	233	615	7e-36	150
rs:WP_038313770	DNA topoisomerase III [Kingella kingae].	28.35	395	239	10	70	432	200	582	7e-36	150
rs:WP_002375953	DNA topoisomerase [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	7e-36	150
rs:WP_000520732	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	27.36	424	291	9	35	454	239	649	7e-36	152
rs:WP_022233792	DNA topoisomerase TopB [Bacteroides sp. CAG:443].	30.23	387	245	9	43	427	246	609	7e-36	150
rs:WP_041348767	DNA topoisomerase [Clostridium botulinum].	29.81	369	230	10	40	398	252	601	7e-36	149
rs:WP_047937035	DNA topoisomerase [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	7e-36	150
rs:WP_041688620	DNA topoisomerase III [[Eubacterium] eligens].	30.00	360	224	11	59	392	286	643	7e-36	150
rs:WP_042751142	topoisomerase I, partial [Lactobacillus brevis].	31.80	327	198	9	80	397	1	311	7e-36	147
rs:WP_008999438	DNA topoisomerase I [Bacteroides sp. D2].	29.41	391	257	10	40	427	241	615	7e-36	150
rs:WP_026903538	DNA topoisomerase III [Pedobacter glucosidilyticus].	30.23	354	228	11	56	402	262	603	7e-36	149
rs:WP_002494670	DNA topoisomerase III [Staphylococcus epidermidis].	28.67	422	275	10	34	450	226	626	7e-36	150
rs:WP_044798599	DNA topoisomerase I [Bacillus thuringiensis].	24.36	431	311	8	33	459	237	656	8e-36	151
rs:WP_015858922	DNA topoisomerase I [Thermococcus gammatolerans].	29.25	465	244	15	40	457	246	672	8e-36	150
rs:WP_022351764	DNA topoisomerase [Firmicutes bacterium CAG:534].	31.09	357	220	10	61	393	288	642	8e-36	150
rs:WP_036117316	DNA topoisomerase III [Lysinibacillus sphaericus].	30.98	410	246	14	59	454	269	655	8e-36	150
rs:WP_022379889	DNA topoisomerase III [Ruminococcus sp. CAG:9].	28.40	412	240	13	35	393	259	668	8e-36	150
rs:WP_009249295	DNA topoisomerase III [Lachnospiraceae bacterium 5_1_57FAA].	30.99	342	212	10	72	392	299	637	8e-36	150
rs:WP_022325293	DNA topoisomerase [Clostridium sp. CAG:798].	32.98	285	174	7	74	348	297	574	8e-36	149
rs:WP_015958118	DNA topoisomerase III [Clostridium botulinum].	30.08	369	229	10	40	398	252	601	8e-36	149
rs:WP_008707501	DNA topoisomerase III [Ruminococcus sp. 5_1_39BFAA].	28.40	412	240	13	35	393	259	668	8e-36	150
tr:S4D4N9_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.01	411	260	7	40	450	215	585	8e-36	150
rs:WP_000520736	DNA topoisomerase I [Bacillus thuringiensis].	27.12	424	292	9	35	454	239	649	9e-36	151
rs:WP_022011721	DNA topoisomerase III [Bacteroides fragilis CAG:558].	33.22	289	184	7	110	396	1	282	9e-36	147
tr:A0A069YSN5_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	32.93	249	162	2	37	284	245	489	9e-36	148
rs:WP_002609437	DNA topoisomerase III [[Clostridium] innocuum].	28.37	430	276	11	35	450	241	652	9e-36	150
rs:WP_002322496	DNA topoisomerase III [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	9e-36	149
rs:WP_008816880	MULTISPECIES: DNA topoisomerase III [Clostridiales].	28.37	430	276	11	35	450	241	652	9e-36	150
rs:WP_042890171	DNA topoisomerase III [Enterococcus faecalis].	27.01	411	260	7	40	450	234	604	9e-36	150
rs:WP_024933790	DNA topoisomerase III [Clostridium botulinum].	30.62	369	227	10	40	398	252	601	9e-36	149
rs:WP_000280355	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	27.02	470	308	12	4	448	219	678	9e-36	150
rs:WP_031770311	DNA topoisomerase III [Staphylococcus aureus].	28.04	378	251	9	59	427	266	631	9e-36	150
rs:WP_007845609	DNA topoisomerase I [Bacteroides dorei].	30.54	370	237	10	60	427	262	613	9e-36	150
rs:WP_047242158	DNA topoisomerase III [Enterococcus cecorum].	25.84	387	247	5	47	431	241	589	9e-36	150
rs:WP_002370882	DNA topoisomerase, partial [Enterococcus faecium].	33.33	312	193	6	57	365	252	551	9e-36	149
tr:C4Z0Y0_EUBE2	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.00	360	224	11	59	392	303	660	1e-35	150
rs:WP_016251036	DNA topoisomerase III [Enterococcus cecorum].	25.84	387	247	5	47	431	241	589	1e-35	150
rs:WP_042832016	DNA topoisomerase III, partial [Xanthomonas citri].	40.11	187	105	2	36	218	70	253	1e-35	143
rs:WP_010538243	DNA topoisomerase I [Bacteroides faecis].	32.10	377	222	12	60	430	263	611	1e-35	150
tr:D4LZE7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.17	384	228	11	51	392	288	669	1e-35	150
rs:WP_022066938	DNA topoisomerase III [Blautia sp. CAG:257].	29.55	396	246	13	35	400	259	651	1e-35	149
rs:WP_016426347	DNA topoisomerase III [Staphylococcus sp. HGB0015].	29.23	390	246	10	74	457	267	632	1e-35	150
rs:WP_011476268	DNA topoisomerase III [Lactobacillus salivarius].	29.26	393	234	9	59	449	253	603	1e-35	150
rs:WP_009289563	DNA topoisomerase III [Anaerostipes sp. 3_2_56FAA].	29.44	360	237	9	47	392	271	627	1e-35	149
rs:WP_045756463	DNA topoisomerase I [Sphingobacterium sp. PM2-P1-29].	29.86	345	231	5	48	391	250	584	1e-35	150
rs:WP_025774955	DNA topoisomerase III [Clostridium botulinum].	30.62	369	227	10	40	398	252	601	1e-35	149
rs:WP_043031848	MULTISPECIES: DNA topoisomerase [Clostridium].	30.08	369	229	10	40	398	252	601	1e-35	149
rs:WP_045539673	DNA topoisomerase [Clostridium botulinum].	30.62	369	227	10	40	398	252	601	1e-35	149
rs:WP_004312901	DNA topoisomerase, partial [Bacteroides xylanisolvens].	32.35	371	217	10	66	430	1	343	1e-35	147
rs:WP_010777183	DNA topoisomerase III [Enterococcus faecium].	33.65	312	192	6	57	365	268	567	1e-35	150
rs:WP_022358423	DNA topoisomerase [Clostridium sp. CAG:43].	28.79	455	254	15	3	392	246	695	1e-35	150
rs:WP_023859599	DNA topoisomerase III [Lactobacillus equi].	28.76	379	221	9	59	431	252	587	1e-35	149
rs:WP_004293865	DNA topoisomerase I [Bacteroides eggerthii].	32.10	377	222	12	60	430	263	611	1e-35	149
rs:WP_013578458	DNA topoisomerase III [Granulicella tundricola].	28.86	402	260	9	59	446	257	646	1e-35	150
rs:WP_044982516	hypothetical protein, partial [Lachnospiraceae bacterium NK4A144].	27.38	431	258	9	3	399	253	662	1e-35	149
rs:WP_008372305	DNA topoisomerase III [Coprococcus comes].	29.43	418	247	14	3	392	245	642	1e-35	149
rs:WP_044005117	DNA topoisomerase III [Lactobacillus salivarius].	29.01	393	235	9	59	449	253	603	1e-35	149
rs:WP_025480388	DNA topoisomerase [Enterococcus faecium].	33.33	315	195	6	54	365	265	567	1e-35	150
rs:WP_011986253	DNA topoisomerase [Clostridium botulinum].	30.62	369	227	10	40	398	252	601	1e-35	149
rs:WP_012721099	DNA topoisomerase III [Clostridium botulinum].	30.08	369	229	10	40	398	252	601	1e-35	149
rs:WP_017465080	DNA topoisomerase III [Staphylococcus epidermidis].	28.17	426	272	10	34	450	226	626	1e-35	150
rs:WP_025481136	DNA topoisomerase [Enterococcus faecium].	33.01	312	194	6	57	365	268	567	1e-35	150
rs:WP_009491930	DNA topoisomerase III [Catellicoccus marimammalium].	30.29	383	211	11	74	449	266	599	1e-35	149
rs:WP_042855301	hypothetical protein [Pseudomonas aeruginosa].	27.54	443	274	13	36	449	240	664	1e-35	150
gp:CP006907_185	DNA topoisomerase family protein [Clostridium botulinum CDC_297]	30.08	369	229	10	40	398	252	601	1e-35	149
rs:WP_002301798	DNA topoisomerase III [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	1e-35	149
rs:WP_042957003	DNA topoisomerase [Enterococcus faecium].	32.80	314	192	7	57	365	268	567	1e-35	150
rs:WP_034736742	DNA topoisomerase I [Chryseobacterium indologenes].	29.81	369	237	7	24	391	237	584	1e-35	149
rs:WP_015729516	DNA topoisomerase III [Staphylococcus pseudintermedius].	28.24	432	275	10	24	449	224	626	1e-35	150
rs:WP_010096889	DNA topoisomerase [Ornithinibacillus scapharcae].	29.37	446	267	17	25	450	235	652	1e-35	150
rs:WP_023980686	hypothetical protein [Pseudomonas aeruginosa].	27.54	443	274	13	36	449	240	664	1e-35	150
tr:M1JAI4_PHODP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.78	258	169	2	31	286	235	487	1e-35	148
rs:WP_002303486	DNA topoisomerase III [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	1e-35	149
tr:R2PQJ8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.80	314	192	7	57	365	269	568	1e-35	150
rs:WP_018708124	DNA topoisomerase [Bacillus fordii].	29.00	431	264	14	36	450	249	653	1e-35	150
rs:WP_023041758	hypothetical protein [Fusobacterium nucleatum].	28.42	387	257	6	50	428	248	622	1e-35	150
rs:WP_042861184	hypothetical protein [Pseudomonas aeruginosa].	27.54	443	274	13	36	449	240	664	1e-35	150
rs:WP_003491116	DNA topoisomerase III [Clostridium sporogenes].	30.08	369	229	10	40	398	252	601	1e-35	149
rs:WP_016172934	DNA topoisomerase III [Enterococcus dispar].	28.88	412	253	9	35	445	230	602	1e-35	149
rs:WP_003486473	DNA topoisomerase III [Clostridium sporogenes].	30.08	369	229	10	40	398	252	601	1e-35	149
rs:WP_003358661	DNA topoisomerase III [Clostridium botulinum].	30.62	369	227	10	40	398	252	601	1e-35	149
rs:WP_002332865	DNA topoisomerase III [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	1e-35	149
rs:WP_011949064	DNA topoisomerase [Clostridium botulinum].	30.62	369	227	10	40	398	252	601	1e-35	149
rs:WP_012099617	DNA topoisomerase III [Clostridium botulinum].	30.62	369	227	10	40	398	252	601	1e-35	149
rs:WP_002311029	DNA topoisomerase [Enterococcus faecium].	35.77	274	151	9	61	328	165	419	1e-35	148
rs:WP_003149058	DNA topoisomerase III [Pseudomonas aeruginosa].	27.54	443	274	13	36	449	240	664	1e-35	150
rs:WP_044383536	DNA topoisomerase [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	1e-35	149
rs:WP_002347713	DNA topoisomerase III [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	1e-35	149
rs:WP_010759745	DNA topoisomerase III [Enterococcus pallens].	27.82	399	248	6	47	445	241	599	1e-35	149
rs:WP_044359601	DNA topoisomerase III [Staphylococcus microti].	27.08	421	284	7	40	457	232	632	1e-35	149
rs:WP_035652017	hypothetical protein, partial [Lachnospiraceae bacterium AC3007].	27.92	419	257	10	3	396	246	644	1e-35	149
rs:WP_032133874	DNA topoisomerase III [Kingella kingae].	28.35	395	239	10	70	432	258	640	1e-35	149
rs:WP_008672316	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	31.83	377	224	12	60	430	263	612	1e-35	149
rs:WP_022759902	DNA topoisomerase III [Butyrivibrio sp. AD3002].	30.94	417	244	17	22	400	245	655	1e-35	149
rs:WP_042700412	DNA topoisomerase I [Thermococcus sp. PK].	29.50	461	247	16	40	457	246	671	1e-35	149
rs:WP_022305902	DNA topoisomerase [Roseburia sp. CAG:380].	30.20	351	213	12	72	392	35	383	1e-35	146
rs:WP_021729338	DNA topoisomerase 1 [Bacillus thuringiensis].	24.59	431	309	8	33	459	237	655	1e-35	150
tr:U2HJ00_LACPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.83	311	193	9	93	397	1	298	1e-35	145
rs:WP_032570624	DNA topoisomerase I [Bacteroides fragilis].	31.70	388	239	11	43	427	246	610	1e-35	149
rs:WP_023043254	DNA topoisomerase III [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	1e-35	149
rs:WP_043482912	hypothetical protein, partial [Geothrix fermentans].	30.40	352	226	6	56	392	263	610	1e-35	148
rs:WP_006045120	DNA topoisomerase I [Prevotella pallens].	29.78	413	256	12	22	425	221	608	1e-35	149
rs:WP_032121812	DNA topoisomerase [Clostridium sp. LF2].	29.00	369	229	10	50	406	262	609	1e-35	149
rs:WP_042988115	DNA topoisomerase I [Bacteroides fragilis].	31.83	377	223	11	60	430	263	611	1e-35	149
rs:WP_028087700	DNA topoisomerase III [Dorea longicatena].	31.02	361	222	11	57	392	287	645	1e-35	149
rs:WP_034549249	DNA topoisomerase III [Clostridiales bacterium VE202-09].	29.33	375	245	10	47	404	277	648	1e-35	149
rs:WP_038308316	DNA topoisomerase III, partial [Kingella kingae].	28.35	395	239	10	70	432	242	624	1e-35	149
rs:WP_002597119	DNA topoisomerase III [Clostridium colicanis].	29.95	434	245	17	49	452	263	667	1e-35	149
rs:WP_044909789	DNA topoisomerase III [Lachnospiraceae bacterium MC2017].	29.86	422	256	13	37	445	225	619	2e-35	149
rs:WP_016171196	DNA topoisomerase III [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	2e-35	149
rs:WP_042092685	hypothetical protein, partial [Escherichia coli].	28.46	383	245	5	36	399	1	373	2e-35	145
rs:WP_035129939	DNA topoisomerase [Clostridium sulfidigenes].	28.66	464	263	15	19	452	244	669	2e-35	149
rs:WP_042986068	DNA topoisomerase I, partial [Bacteroides fragilis].	32.10	377	222	10	60	430	221	569	2e-35	149
rs:WP_021774656	DNA topoisomerase III [Oribacterium sp. oral taxon 078].	30.68	365	232	9	47	395	276	635	2e-35	149
rs:WP_032572319	DNA topoisomerase I [Bacteroides fragilis].	31.70	388	239	11	43	427	246	610	2e-35	149
rs:WP_032567475	DNA topoisomerase I, partial [Bacteroides fragilis].	31.83	377	223	11	60	430	251	599	2e-35	149
tr:C9LHI7_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEX71447.1};	28.67	429	276	11	22	443	18	423	2e-35	147
tr:Q3RFU2_XYLFS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	69.07	97	30	0	29	125	225	321	2e-35	145
tr:A0A0D0FB34_LACBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.39	318	190	9	89	397	4	305	2e-35	146
tr:M5AH10_LACBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.65	316	195	8	89	397	4	305	2e-35	146
rs:WP_038284267	DNA topoisomerase, partial [Xylella fastidiosa].	67.00	100	33	0	29	128	245	344	2e-35	145
rs:WP_002992175	MULTISPECIES: DNA topoisomerase [Myroides].	30.60	317	206	7	70	384	272	576	2e-35	149
rs:WP_038231122	DNA topoisomerase, partial [Xylella fastidiosa].	69.07	97	30	0	29	125	245	341	2e-35	145
rs:WP_009221177	DNA topoisomerase III [Lachnospiraceae oral taxon 107].	32.34	368	220	12	37	398	225	569	2e-35	148
rs:WP_025481450	DNA topoisomerase III [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	2e-35	149
rs:WP_005909733	DNA topoisomerase III [Fusobacterium nucleatum].	26.97	393	255	8	50	428	248	622	2e-35	149
rs:WP_025067905	DNA topoisomerase I [Prevotella denticola].	31.30	361	225	9	22	375	221	565	2e-35	149
rs:WP_007709571	hypothetical protein [[Clostridium] asparagiforme].	31.18	340	219	5	43	378	231	559	2e-35	149
rs:WP_032944498	DNA topoisomerase I [Bacteroides vulgatus].	31.83	377	223	11	60	430	263	611	2e-35	149
rs:WP_007716460	DNA topoisomerase III [[Clostridium] asparagiforme].	31.59	421	241	16	47	445	235	630	2e-35	149
rs:WP_044180300	DNA topoisomerase III, partial [Photobacterium damselae].	32.02	253	165	2	31	281	235	482	2e-35	147
tr:C9BZ11_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.33	312	193	6	57	365	298	597	2e-35	149
rs:WP_021560353	hypothetical protein [Escherichia coli].	27.51	429	269	7	31	440	256	661	2e-35	149
rs:WP_001235769	hypothetical protein [Escherichia coli].	27.17	427	273	6	31	440	256	661	2e-35	149
rs:WP_005801814	DNA topoisomerase I [Bacteroides fragilis].	30.77	338	220	8	60	393	262	589	2e-35	149
rs:WP_039430831	DNA topoisomerase I [Porphyromonas gulae].	29.27	386	251	9	47	427	248	616	2e-35	149
rs:WP_022465005	DNA topoisomerase III [Clostridium sp. CAG:277].	30.77	351	211	11	72	392	315	663	2e-35	149
rs:WP_031893288	DNA topoisomerase [Staphylococcus aureus].	29.88	405	247	11	56	444	273	656	2e-35	149
rs:WP_040239307	DNA topoisomerase [Xanthomonas citri].	30.99	413	238	12	40	428	260	649	2e-35	150
rs:WP_009215951	DNA topoisomerase III [Oribacterium sp. oral taxon 078].	30.68	365	232	9	47	395	276	635	2e-35	148
tr:F0Z4H4_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.47	430	247	15	47	436	259	676	2e-35	149
rs:WP_006060481	DNA topoisomerase III [Holdemania filiformis].	30.45	358	232	7	47	398	237	583	2e-35	149
rs:WP_039099504	DNA topoisomerase III [Lactobacillus curvatus].	29.72	387	238	7	6	389	199	554	2e-35	149
rs:WP_032584277	DNA topoisomerase I [Bacteroides fragilis].	31.70	388	239	11	43	427	246	610	2e-35	149
rs:WP_001832808	MULTISPECIES: DNA topoisomerase [Staphylococcus].	29.88	405	247	11	56	444	273	656	2e-35	149
rs:WP_003012643	DNA topoisomerase [Sphingobacterium spiritivorum].	30.97	352	230	6	43	391	244	585	2e-35	149
rs:WP_025480889	DNA topoisomerase III [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	2e-35	149
rs:WP_019977041	DNA topoisomerase [Empedobacter brevis].	30.77	338	223	5	48	384	250	577	2e-35	149
rs:WP_032569262	DNA topoisomerase I [Bacteroides fragilis].	31.83	377	223	11	60	430	263	611	2e-35	149
rs:WP_007764104	DNA topoisomerase I [Bacteroides finegoldii].	32.10	377	222	10	60	430	263	611	2e-35	149
rs:WP_023039176	hypothetical protein [Fusobacterium nucleatum].	26.97	393	255	8	50	428	248	622	2e-35	149
rs:WP_043543456	hypothetical protein [Pseudomonas aeruginosa].	27.54	443	274	13	36	449	240	664	2e-35	149
rs:WP_002346936	DNA topoisomerase III [Enterococcus faecium].	33.33	312	193	6	57	365	268	567	2e-35	149
rs:WP_032563947	DNA topoisomerase I [Bacteroides fragilis].	31.83	377	223	11	60	430	263	611	2e-35	149
rs:WP_032569384	DNA topoisomerase I [Bacteroides fragilis].	31.83	377	223	11	60	430	263	611	2e-35	149
rs:WP_028298779	DNA topoisomerase I [Olivibacter sitiensis].	29.27	369	239	7	24	391	237	584	2e-35	149
rs:WP_032593111	DNA topoisomerase I [Bacteroides fragilis].	31.70	388	239	11	43	427	246	610	2e-35	149
rs:WP_044132009	DNA topoisomerase I [Bacteroides fragilis].	31.83	377	223	11	60	430	263	611	2e-35	149
rs:WP_005603390	DNA topoisomerase III [Butyrivibrio crossotus].	31.56	358	222	11	55	392	281	635	2e-35	148
tr:R5HV76_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.30	363	225	11	57	393	282	642	2e-35	149
rs:WP_021861155	DNA topoisomerase III [Dorea sp. CAG:105].	30.32	376	230	13	47	392	271	644	2e-35	149
rs:WP_005861699	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	31.83	377	224	12	60	430	263	612	2e-35	149
rs:WP_005790822	MULTISPECIES: DNA topoisomerase I [Bacteroidetes].	31.83	377	223	11	60	430	263	611	2e-35	149
rs:WP_004564283	DNA topoisomerase III [Lactobacillus salivarius].	29.01	393	235	9	59	449	253	603	2e-35	149
rs:WP_042367709	DNA topoisomerase I [Bacteroidaceae bacterium MS4].	32.04	334	208	7	59	384	259	581	2e-35	149
rs:WP_012703748	DNA topoisomerase III [Clostridium botulinum].	30.62	369	227	10	40	398	252	601	2e-35	148
rs:WP_025481300	DNA topoisomerase [Enterococcus faecium].	31.85	314	195	7	57	365	268	567	2e-35	149
rs:WP_008979754	DNA topoisomerase III [Peptoclostridium difficile].	31.49	343	220	5	40	378	228	559	2e-35	149
rs:WP_024733189	DNA topoisomerase III [Clostridiales bacterium VE202-14].	31.07	412	253	12	47	449	235	624	2e-35	149
tr:R6P0H2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.21	384	224	12	51	392	288	669	2e-35	149
rs:WP_032567764	DNA topoisomerase I [Bacteroides fragilis].	31.83	377	223	11	60	430	263	611	2e-35	149
tr:I2WFJ6_ECOLX	SubName: Full=Topoisomerase DNA-binding C4 zinc finger domain protein {ECO:0000313|EMBL:EII23424.1};	30.88	285	173	5	182	458	1	269	2e-35	145
rs:WP_023249656	DNA topoisomerase III, partial [Salmonella enterica].	42.26	168	95	2	36	203	251	416	2e-35	146
rs:WP_021639559	DNA topoisomerase, partial [Clostridium sp. KLE 1755].	32.11	327	207	5	63	385	10	325	2e-35	147
rs:WP_041890459	DNA topoisomerase I [Myroides profundi].	30.60	317	206	7	70	384	272	576	2e-35	149
rs:WP_000520749	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	26.42	424	295	9	35	454	239	649	2e-35	150
rs:WP_032567317	DNA topoisomerase I [Bacteroides fragilis].	31.83	377	223	11	60	430	263	611	2e-35	149
rs:WP_047035846	DNA topoisomerase III [Lactobacillus salivarius].	29.01	393	235	9	59	449	253	603	2e-35	149
tr:D1W4E5_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.83	377	223	11	60	430	282	630	2e-35	149
rs:WP_014568628	DNA topoisomerase III [Lactobacillus salivarius].	29.01	393	235	9	59	449	253	603	2e-35	149
rs:WP_029491115	DNA topoisomerase III [Fusobacterium hwasookii].	32.60	319	201	6	74	382	269	583	2e-35	148
rs:WP_047340951	DNA topoisomerase III [Enterococcus cecorum].	25.58	387	248	5	47	431	241	589	2e-35	149
rs:WP_010074359	DNA topoisomerase [Clostridium cellulovorans].	29.40	415	257	12	48	450	265	655	2e-35	149
rs:WP_004604812	DNA topoisomerase III [[Clostridium] scindens].	30.22	407	258	11	47	445	235	623	2e-35	149
rs:WP_026882027	DNA topoisomerase [Clostridium akagii].	28.47	425	252	14	50	452	263	657	2e-35	149
rs:WP_035314400	DNA topoisomerase III [Clostridium sp. D5].	30.47	430	247	15	47	436	271	688	3e-35	148
rs:WP_022056443	DNA topoisomerase III [Clostridium sp. CAG:167].	30.02	433	240	16	3	401	247	650	3e-35	148
rs:WP_031884038	DNA topoisomerase III [Staphylococcus aureus].	28.31	378	250	9	59	427	266	631	3e-35	149
rs:WP_022438332	DNA topoisomerase III [Clostridium sp. CAG:411].	30.68	352	215	12	72	396	301	650	3e-35	148
rs:WP_004563798	DNA topoisomerase III [Lactobacillus salivarius].	29.52	393	233	9	59	449	253	603	3e-35	149
tr:J9C8M6_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.83	289	183	6	36	321	244	521	3e-35	147
rs:WP_005802302	DNA topoisomerase I [Bacteroides fragilis].	30.83	373	233	11	60	430	263	612	3e-35	149
rs:WP_007660662	DNA topoisomerase I [Bacteroides intestinalis].	32.10	377	222	10	60	430	263	611	3e-35	149
rs:WP_047437206	DNA topoisomerase I [Chryseobacterium sp. YR561].	29.27	386	250	9	43	423	244	611	3e-35	148
rs:WP_034982849	DNA topoisomerase III [Lactobacillus salivarius].	28.75	393	236	9	59	449	253	603	3e-35	148
rs:WP_009131566	DNA topoisomerase III [Bacteroides oleiciplenus].	33.13	335	203	10	53	384	278	594	3e-35	149
rs:WP_022389358	DNA topoisomerase III [Ruminococcus obeum CAG:39].	29.79	386	231	13	47	399	271	649	3e-35	148
rs:WP_005809261	DNA topoisomerase I [Bacteroides fragilis].	31.17	369	231	9	60	427	263	609	3e-35	148
rs:WP_004291456	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	32.10	377	222	10	60	430	263	611	3e-35	148
rs:WP_015391084	DNA topoisomerase 3 [Clostridium saccharoperbutylacetonicum].	30.79	419	236	15	56	452	269	655	3e-35	149
rs:WP_031896211	DNA topoisomerase III [Staphylococcus aureus].	28.31	378	250	9	59	427	266	631	3e-35	149
rs:WP_038399531	topoisomerase [Staphylococcus epidermidis].	28.67	422	275	10	34	450	226	626	3e-35	149
rs:WP_002996062	MULTISPECIES: DNA topoisomerase [Bacteroidetes].	30.68	352	231	6	43	391	244	585	3e-35	148
rs:WP_003699035	DNA topoisomerase [Lactobacillus salivarius].	27.45	408	267	9	57	450	270	662	3e-35	149
tr:A0A015W1D8_BACFG	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EXY92028.1};	30.85	376	229	11	60	430	131	480	3e-35	147
tr:R8K356_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.47	424	299	9	35	454	1	411	3e-35	147
rs:WP_021825728	DNA topoisomerase III [Prevotella salivae].	28.85	409	265	10	22	425	221	608	3e-35	148
sp:TOP1_PYRAB	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	30.96	436	236	18	47	457	252	647	3e-35	148
rs:WP_047982196	DNA topoisomerase [Ornithinibacillus contaminans].	29.12	443	269	14	27	450	236	652	3e-35	149
rs:WP_036616528	DNA topoisomerase I [Parabacteroides distasonis].	30.27	370	233	9	60	427	263	609	3e-35	148
rs:WP_006439044	DNA topoisomerase III [[Clostridium] hiranonis].	28.73	362	230	8	38	392	241	581	3e-35	149
rs:WP_021960535	DNA topoisomerase III [Butyrivibrio crossotus CAG:259].	31.56	358	222	11	55	392	281	635	3e-35	148
rs:WP_025577250	DNA topoisomerase III [Blautia wexlerae].	28.09	445	245	15	3	393	245	668	3e-35	149
rs:WP_000280354	hypothetical protein [Bacillus cereus].	28.47	411	265	11	57	448	278	678	3e-35	149
rs:WP_021943206	DNA topoisomerase [Clostridium sp. CAG:264].	30.88	353	222	11	56	392	281	627	3e-35	148
rs:WP_008645574	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	30.27	370	233	9	60	427	263	609	3e-35	148
rs:WP_047774676	DNA topoisomerase III [[Eubacterium] fissicatena].	30.47	430	247	15	47	436	271	688	3e-35	148
rs:WP_044345686	DNA topoisomerase III, partial [Pseudomonas meliae].	34.94	249	153	4	36	278	244	489	3e-35	146
rs:WP_006256849	DNA topoisomerase [Myroides odoratimimus].	30.28	317	207	7	70	384	272	576	3e-35	148
rs:WP_022502109	DNA topoisomerase III [Eubacterium sp. CAG:76].	30.97	352	218	10	62	392	291	638	4e-35	148
rs:WP_042971014	DNA topoisomerase I, partial [Bacteroides fragilis].	30.85	376	229	11	60	430	142	491	4e-35	147
rs:WP_033143458	DNA topoisomerase III [Blautia producta].	30.41	342	215	11	74	395	301	639	4e-35	148
rs:WP_040015482	DNA topoisomerase III, partial [Dorea formicigenerans].	30.77	390	212	13	57	392	282	667	4e-35	148
rs:WP_032542968	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	32.10	377	222	10	60	430	263	611	4e-35	148
rs:WP_021844917	DNA topoisomerase [Blautia hydrogenotrophica CAG:147].	30.72	345	214	10	72	395	168	508	4e-35	147
rs:WP_008592302	DNA topoisomerase III [Salimicrobium jeotgali].	26.96	408	263	10	59	454	269	653	4e-35	148
rs:WP_010750414	DNA topoisomerase III, partial [Enterococcus villorum].	26.19	443	284	9	6	445	164	566	4e-35	147
rs:WP_003705193	DNA topoisomerase III [Lactobacillus salivarius].	28.75	393	236	9	59	449	253	603	4e-35	148
rs:WP_031390120	DNA topoisomerase III [Clostridium sp. KNHs209].	28.54	403	240	12	35	392	259	658	4e-35	148
rs:WP_026497541	DNA topoisomerase III [Butyrivibrio sp. WCD2001].	30.38	418	246	16	22	400	245	656	4e-35	148
rs:WP_043313879	DNA topoisomerase III, partial [Bacillus cereus].	31.94	288	182	6	36	320	244	520	4e-35	146
rs:WP_016121292	DNA topoisomerase III [Bacillus cereus].	27.25	411	270	10	59	454	270	666	4e-35	148
rs:WP_038699441	DNA topoisomerase I [Sphingobacterium sp. ML3W].	30.14	345	230	5	48	391	250	584	4e-35	148
rs:WP_034215261	DNA topoisomerase [Lachnoanaerobaculum sp. MSX33].	33.42	368	216	12	37	398	225	569	5e-35	147
rs:WP_032566369	DNA topoisomerase I [Bacteroides fragilis].	30.67	388	250	11	43	427	246	617	5e-35	148
rs:WP_037441084	DNA topoisomerase I [Pedobacter antarcticus].	29.48	346	233	5	47	391	249	584	5e-35	148
tr:B0G5U8_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.77	390	212	13	57	392	282	667	5e-35	148
rs:WP_019724267	hypothetical protein, partial [Enterococcus mundtii].	27.48	433	267	10	18	445	3	393	5e-35	146
tr:J8BJA9_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.47	424	299	9	35	454	1	411	5e-35	146
rs:WP_038330896	DNA topoisomerase I [Empedobacter falsenii].	30.06	346	229	7	48	391	250	584	5e-35	148
rs:WP_021749501	MULTISPECIES: DNA topoisomerase [Oscillibacter].	31.49	343	220	5	40	378	228	559	5e-35	148
rs:WP_005680567	DNA topoisomerase I [Bacteroides caccae].	31.56	377	225	12	60	430	263	612	5e-35	148
rs:WP_036880331	DNA topoisomerase I [Prevotella buccalis].	32.10	377	222	10	60	430	263	611	5e-35	148
rs:WP_038233057	DNA topoisomerase, partial [Xylella fastidiosa].	66.00	100	34	0	29	128	245	344	5e-35	144
rs:WP_021635830	DNA topoisomerase III [Clostridium sp. KLE 1755].	30.95	391	235	14	35	392	277	665	5e-35	148
tr:W6M0Y1_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.99	384	229	10	47	399	282	660	5e-35	150
rs:WP_031877274	DNA topoisomerase III, partial [Staphylococcus aureus].	30.46	302	186	5	35	328	227	512	5e-35	146
rs:WP_041516059	DNA topoisomerase I [Flavobacterium hibernum].	29.48	346	233	5	47	391	249	584	5e-35	147
rs:WP_028896492	DNA topoisomerase I [Prevotella sp. HUN102].	31.09	357	219	9	74	426	276	609	5e-35	147
tr:L2JIY6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.29	312	190	6	57	365	92	391	5e-35	146
rs:WP_032602824	DNA topoisomerase I, partial [Bacteroides fragilis].	31.30	377	226	12	60	430	263	612	5e-35	147
rs:WP_009221186	DNA topoisomerase III [Lachnospiraceae oral taxon 107].	32.88	368	218	12	37	398	225	569	5e-35	147
tr:W4V0T6_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	33.00	297	188	5	47	342	248	534	5e-35	146
rs:WP_032562869	DNA topoisomerase I [Bacteroides fragilis].	30.67	388	250	11	43	427	246	617	5e-35	148
rs:WP_021914626	DNA topoisomerase [Firmicutes bacterium CAG:24].	31.91	351	208	11	72	393	285	633	5e-35	147
tr:D7GWX3_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.40	432	239	13	3	392	248	655	5e-35	147
rs:WP_047929706	DNA topoisomerase III [Enterococcus faecium].	27.50	400	249	8	47	445	207	566	5e-35	147
rs:WP_021983043	DNA topoisomerase III [Eubacterium sp. CAG:603].	28.85	416	237	15	22	392	246	647	6e-35	147
rs:WP_032569313	DNA topoisomerase I [Bacteroides fragilis].	31.30	377	226	12	60	430	263	612	6e-35	147
rs:WP_026690239	DNA topoisomerase III [Bacillus aurantiacus].	28.37	423	258	18	57	453	264	667	6e-35	148
rs:WP_033602881	DNA topoisomerase, partial [Enterococcus faecium].	35.05	291	169	7	52	336	40	316	6e-35	143
rs:WP_032557817	DNA topoisomerase I [Bacteroides fragilis].	31.30	377	226	12	60	430	263	612	6e-35	147
rs:WP_041153557	hypothetical protein [Lactobacillus plantarum].	32.17	314	196	7	89	397	4	305	6e-35	145
rs:WP_003710611	DNA topoisomerase III [Lactobacillus salivarius].	28.75	393	236	9	59	449	253	603	6e-35	147
rs:WP_004308745	MULTISPECIES: DNA topoisomerase I [Bacteroides].	29.76	373	240	10	59	427	259	613	6e-35	147
rs:WP_042707682	DNA topoisomerase I [Methanobrevibacter wolinii].	28.25	446	278	12	18	458	220	628	6e-35	147
rs:WP_008403089	DNA topoisomerase III [Clostridium sp. L2-50].	30.88	353	222	11	56	392	281	627	7e-35	147
rs:WP_033711194	DNA topoisomerase I, partial [Bacillus cereus].	25.47	424	299	9	35	454	16	426	7e-35	146
rs:WP_000520745	DNA topoisomerase I [Bacillus cereus].	26.42	424	295	9	35	454	239	649	7e-35	149
rs:WP_013632693	DNA topoisomerase [Pseudopedobacter saltans].	30.75	348	224	7	48	391	250	584	7e-35	147
rs:WP_028529857	DNA topoisomerase III [Ruminococcus gauvreauii].	29.81	369	237	12	45	395	273	637	7e-35	147
rs:WP_034638379	DNA topoisomerase III, partial [Bacillus manliponensis].	30.90	288	187	5	36	321	244	521	7e-35	146
tr:R8NBQ2_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.07	290	184	7	56	341	266	546	7e-35	146
rs:WP_035639814	hypothetical protein, partial [Lachnospiraceae bacterium ND2006].	31.69	344	191	12	74	392	301	625	7e-35	147
rs:WP_042688973	DNA topoisomerase I [Thermococcus nautili].	28.78	469	248	13	40	457	246	679	7e-35	147
rs:WP_044797016	DNA topoisomerase I [Bacillus cereus].	26.18	424	296	9	35	454	239	649	7e-35	149
rs:WP_029486302	DNA topoisomerase III [Enterococcus gallinarum].	26.76	411	260	7	40	450	234	603	7e-35	147
rs:WP_029902380	DNA topoisomerase I [Prevotella sp. 10(H)].	28.61	381	250	10	18	385	217	588	7e-35	147
rs:WP_044531588	DNA topoisomerase III, partial [Herbaspirillum sp. B65].	33.10	284	177	5	109	385	2	279	7e-35	146
tr:A0A011P1L8_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.59	292	160	7	40	314	168	445	7e-35	145
rs:WP_013666927	DNA topoisomerase III [Sphingobacterium sp. 21].	29.08	337	226	9	59	393	267	592	7e-35	146
rs:WP_001094108	hypothetical protein [Bacillus cereus].	28.37	416	271	10	59	454	274	682	7e-35	147
rs:WP_036872688	DNA topoisomerase I [Porphyromonas macacae].	29.02	386	252	9	47	427	248	616	7e-35	147
rs:WP_009461692	hypothetical protein [Lachnospiraceae bacterium 2_1_46FAA].	29.31	389	251	7	47	426	235	608	7e-35	147
rs:WP_005944290	DNA topoisomerase III [Bacteroides massiliensis].	30.27	370	233	9	60	427	263	609	8e-35	147
rs:WP_014121655	DNA topoisomerase I [Thermococcus sp. AM4].	29.00	469	247	13	40	457	246	679	8e-35	147
rs:WP_019389429	hypothetical protein [Kingella kingae].	28.10	395	240	10	70	432	200	582	8e-35	147
rs:WP_019150869	DNA topoisomerase I [Alistipes senegalensis].	33.02	324	200	7	71	393	275	582	8e-35	147
rs:WP_009662899	DNA topoisomerase III [Lachnoanaerobaculum sp. ICM7].	32.34	368	220	12	37	398	225	569	8e-35	146
rs:WP_000520748	DNA topoisomerase I [Bacillus cereus].	26.42	424	295	9	35	454	239	649	8e-35	148
rs:WP_005470120	MULTISPECIES: DNA topoisomerase III [Enterococcus].	26.76	411	260	7	40	450	234	603	8e-35	147
rs:WP_003128167	DNA topoisomerase III [Enterococcus gallinarum].	26.76	411	260	7	40	450	234	603	8e-35	147
rs:WP_006775974	DNA topoisomerase III [Hungatella hathewayi].	28.96	404	243	13	35	397	260	660	8e-35	147
rs:WP_004270975	DNA topoisomerase III [Lactobacillus curvatus].	29.46	387	239	7	6	389	199	554	8e-35	147
rs:WP_009004429	DNA topoisomerase III [Clostridium sp. D5].	30.62	356	228	7	40	385	232	578	8e-35	147
rs:WP_000520750	DNA topoisomerase I [Bacillus thuringiensis].	26.06	426	294	10	35	454	239	649	8e-35	148
tr:T0VIC8_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.76	411	260	7	40	450	215	584	9e-35	147
tr:Q3MN56_LACPA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.87	320	189	9	89	397	4	305	9e-35	144
rs:WP_043070392	hypothetical protein, partial [Aneurinibacillus migulanus].	28.34	374	252	8	22	385	231	598	9e-35	147
rs:WP_016316298	DNA topoisomerase III [Anaerotruncus sp. G3(2012)].	31.36	338	215	7	66	397	256	582	9e-35	147
rs:WP_023519206	DNA topoisomerase III, partial [Enterococcus mundtii].	28.36	402	243	9	47	445	207	566	9e-35	146
rs:WP_013295046	DNA topoisomerase I [Methanothermobacter marburgensis].	28.05	435	263	12	30	453	228	623	9e-35	147
rs:WP_029285251	DNA topoisomerase I [Pedobacter sp. R20-19].	30.70	329	209	11	59	382	267	581	9e-35	146
rs:WP_022004444	DNA topoisomerase III [Firmicutes bacterium CAG:194].	30.14	418	245	14	3	392	245	643	9e-35	147
rs:WP_012020800	DNA topoisomerase [Metallosphaera sedula].	30.53	357	203	8	47	398	237	553	9e-35	147
rs:WP_043935294	MULTISPECIES: hypothetical protein [Bacillus].	28.28	396	243	11	67	450	267	633	1e-34	147
rs:WP_007653064	DNA topoisomerase I [Parabacteroides goldsteinii].	30.13	375	239	11	56	427	259	613	1e-34	147
rs:WP_026706431	DNA topoisomerase I [Flavobacterium soli].	29.57	345	232	5	48	391	250	584	1e-34	147
rs:WP_039451807	DNA topoisomerase I [Pedobacter glucosidilyticus].	29.73	370	241	11	38	402	248	603	1e-34	146
rs:WP_000520747	DNA topoisomerase I [Bacillus cereus].	26.18	424	296	9	35	454	239	649	1e-34	148
tr:A0A0D0PZV8_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.28	396	243	11	67	450	278	644	1e-34	147
rs:WP_034688920	DNA topoisomerase III [Enterococcus mundtii].	28.36	402	243	9	47	445	207	566	1e-34	146
rs:WP_010652035	DNA topoisomerase [Oceanobacillus massiliensis].	28.21	429	268	13	36	450	249	651	1e-34	147
rs:WP_006266598	DNA topoisomerase [Myroides odoratimimus].	30.60	317	206	7	70	384	272	576	1e-34	147
rs:WP_023056934	DNA topoisomerase [Prevotella sp. BV3P1].	30.56	373	234	11	60	430	263	612	1e-34	147
tr:J1BJU3_STREE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.78	363	217	10	37	396	180	518	1e-34	145
rs:WP_002455007	DNA topoisomerase III [Staphylococcus hominis].	24.76	424	285	8	35	449	227	625	1e-34	147
rs:WP_033918726	DNA topoisomerase, partial [Enterococcus faecalis].	33.66	303	185	6	56	354	268	558	1e-34	145
rs:WP_026490610	DNA topoisomerase III [Butyrivibrio sp. XPD2002].	31.11	405	238	14	35	400	259	661	1e-34	147
rs:WP_009268350	DNA topoisomerase III [Lachnospiraceae bacterium 1_4_56FAA].	30.26	390	226	12	47	392	271	658	1e-34	147
rs:WP_021941314	DNA topoisomerase [Clostridium sp. CAG:632].	31.76	340	210	10	72	392	300	636	1e-34	146
tr:D4LVC5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.77	364	227	8	37	386	220	572	1e-34	147
rs:WP_000520746	MULTISPECIES: DNA topoisomerase I [Bacillus].	26.18	424	296	9	35	454	239	649	1e-34	148
rs:WP_035916419	DNA topoisomerase [Fusobacterium necrophorum].	32.70	367	220	10	37	400	226	568	1e-34	145
rs:WP_005812009	DNA topoisomerase I [Bacteroides fragilis].	33.14	341	200	9	60	394	263	581	1e-34	146
rs:WP_000520751	DNA topoisomerase I [Bacillus cereus].	26.18	424	296	9	35	454	239	649	1e-34	148
rs:WP_006844208	DNA topoisomerase I [Dysgonomonas mossii].	31.08	325	214	6	61	384	263	578	1e-34	147
rs:WP_039644438	DNA topoisomerase III [Staphylococcus hyicus].	27.42	423	280	8	40	457	232	632	1e-34	147
rs:WP_022032138	DNA topoisomerase III [Clostridium hathewayi CAG:224].	28.47	404	245	12	35	397	260	660	1e-34	146
rs:WP_008653004	DNA topoisomerase I [Bacteroides sp. 3_1_33FAA].	30.29	373	238	10	59	427	259	613	1e-34	146
rs:WP_010861635	DNA topoisomerase III [Enterococcus faecium].	32.37	312	196	6	57	365	268	567	1e-34	147
rs:WP_021773317	DNA topoisomerase [Oribacterium sp. oral taxon 078].	29.77	393	245	10	61	445	250	619	1e-34	146
rs:WP_043859254	DNA topoisomerase III [Staphylococcus aureus].	29.24	407	252	12	57	454	268	647	1e-34	146
rs:WP_007656370	DNA topoisomerase I [Parabacteroides goldsteinii].	30.81	370	231	9	60	427	263	609	1e-34	146
rs:WP_021870156	DNA topoisomerase [Clostridium sp. CAG:7].	29.87	385	228	13	47	392	276	657	1e-34	146
tr:H3KHJ1_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.17	358	205	9	86	425	2	332	1e-34	145
rs:WP_021403859	DNA topoisomerase [Peptoclostridium difficile].	29.13	357	225	10	47	396	249	584	1e-34	147
rs:WP_044270609	DNA topoisomerase I [Candidatus Bacteroides timonensis].	29.95	414	260	12	16	427	228	613	1e-34	146
rs:WP_006261870	DNA topoisomerase [Myroides odoratimimus].	29.18	377	248	8	48	421	250	610	1e-34	146
rs:WP_014262670	MULTISPECIES: DNA topoisomerase III [Firmicutes].	32.78	363	217	10	37	396	225	563	1e-34	145
tr:A0A022NBM7_ENTMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.36	402	243	9	47	445	241	600	1e-34	146
rs:WP_005947007	DNA topoisomerase III [Blautia hydrogenotrophica].	31.07	338	216	7	66	397	256	582	1e-34	146
rs:WP_038309401	DNA topoisomerase III [Kingella kingae].	28.10	395	240	10	70	432	258	640	1e-34	146
rs:WP_033160575	DNA topoisomerase I, partial [Bacteroides cellulosilyticus].	30.36	359	230	9	71	427	96	436	1e-34	145
rs:WP_018676469	DNA topoisomerase I [Riemerella columbina].	31.83	377	223	10	60	430	263	611	1e-34	146
rs:WP_039417014	DNA topoisomerase I [Porphyromonas gingivalis].	28.57	385	256	8	47	427	248	617	2e-34	146
rs:WP_026901859	DNA topoisomerase [Peptostreptococcaceae bacterium VA2].	28.57	357	227	10	47	396	249	584	2e-34	147
rs:WP_033795056	DNA topoisomerase [Enterococcus faecium].	32.50	320	194	6	57	365	268	576	2e-34	147
rs:WP_032567528	DNA topoisomerase I [Bacteroides fragilis].	31.96	388	237	13	47	427	249	616	2e-34	146
rs:WP_007789451	DNA topoisomerase III [Peptostreptococcus stomatis].	27.08	373	249	7	35	402	237	591	2e-34	147
rs:WP_046147969	DNA topoisomerase I [Parabacteroides goldsteinii].	29.65	371	234	9	60	427	263	609	2e-34	146
tr:V5M5L7_BACTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.03	396	244	11	67	450	276	642	2e-34	146
rs:WP_000520733	DNA topoisomerase I [Bacillus thuringiensis].	27.34	428	286	11	35	454	239	649	2e-34	147
rs:WP_042371906	DNA topoisomerase I [Bacteroidaceae bacterium MS4].	29.36	419	267	13	35	450	236	628	2e-34	146
rs:WP_027641614	DNA topoisomerase III [[Clostridium] clostridioforme].	28.94	387	235	13	43	392	272	655	2e-34	146
rs:WP_035790822	DNA topoisomerase III [Butyrivibrio sp. FC2001].	31.30	393	229	14	47	400	271	661	2e-34	146
rs:WP_027147611	DNA topoisomerase [Methylobacter tundripaludum].	28.79	389	235	8	39	395	233	611	2e-34	147
rs:WP_032559101	MULTISPECIES: DNA topoisomerase I [Bacteroides].	31.83	377	223	10	60	430	263	611	2e-34	146
rs:WP_003010128	DNA topoisomerase [Sphingobacterium spiritivorum].	30.77	338	220	8	48	382	250	576	2e-34	146
rs:WP_034735059	DNA topoisomerase I [Chryseobacterium indologenes].	29.57	345	232	5	48	391	250	584	2e-34	146
rs:WP_032594406	DNA topoisomerase I [Bacteroides fragilis].	31.30	377	226	12	60	430	263	612	2e-34	146
rs:WP_047990476	DNA topoisomerase [Bacillus pseudalcaliphilus].	28.26	407	253	12	59	450	271	653	2e-34	146
rs:WP_006773686	DNA topoisomerase III, partial [[Clostridium] hathewayi].	29.43	418	259	12	40	445	49	442	2e-34	145
rs:WP_022498679	DNA topoisomerase [Firmicutes bacterium CAG:95].	28.73	449	262	15	3	413	245	673	2e-34	146
rs:WP_033628386	DNA topoisomerase, partial [Enterococcus faecalis].	33.77	308	186	7	52	354	127	421	2e-34	144
rs:WP_043924753	hypothetical protein [Bacillus thuringiensis].	28.03	396	244	11	67	450	267	633	2e-34	146
rs:WP_025489788	DNA topoisomerase III [Clostridiales bacterium VE202-27].	30.18	391	238	13	35	392	277	665	2e-34	146
rs:WP_010736168	DNA topoisomerase III, partial [Enterococcus mundtii].	28.36	402	243	9	47	445	207	566	2e-34	145
rs:WP_042512118	DNA topoisomerase I [Bacillus cereus].	27.38	431	282	13	35	454	239	649	2e-34	147
rs:WP_047094745	DNA topoisomerase I [Chryseobacterium indologenes].	29.57	345	232	5	48	391	250	584	2e-34	146
tr:F9DSM1_9BACL	SubName: Full=Conjugal transfer nickase/helicase TraI {ECO:0000313|EMBL:EGQ26195.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EGQ26195.1};	29.78	319	192	9	155	456	24	327	2e-34	143
rs:WP_016839134	DNA topoisomerase [Ureibacillus thermosphaericus].	30.02	403	232	14	67	450	279	650	2e-34	146
rs:WP_024038076	DNA topoisomerase [Intestinibacter bartlettii].	28.15	444	251	15	47	450	249	664	2e-34	146
rs:WP_000214012	DNA topoisomerase III [Staphylococcus aureus].	28.16	419	265	13	41	454	259	646	2e-34	146
rs:WP_027117982	DNA topoisomerase III [Lachnospiraceae bacterium YSB2008].	30.84	347	220	9	61	392	320	661	2e-34	146
rs:WP_009905893	DNA topoisomerase [Peptoclostridium difficile].	29.13	357	225	10	47	396	129	464	2e-34	145
rs:WP_021956947	DNA topoisomerase [Eubacterium sp. CAG:115].	29.52	393	257	9	52	432	240	624	2e-34	146
rs:WP_020367826	DNA topoisomerase III, partial [Staphylococcus epidermidis].	29.91	341	213	6	34	365	226	549	2e-34	145
rs:WP_016286623	DNA topoisomerase III [Lachnospiraceae bacterium 3-1].	31.20	391	240	11	47	426	234	606	2e-34	146
rs:WP_013666865	DNA topoisomerase [Sphingobacterium sp. 21].	32.09	349	218	9	48	391	250	584	2e-34	146
rs:WP_017258167	DNA topoisomerase III [Pedobacter arcticus].	30.53	357	227	11	57	406	265	607	2e-34	145
rs:WP_009296637	DNA topoisomerase III [Clostridium sp. 7_3_54FAA].	30.40	352	228	7	40	385	230	570	2e-34	146
rs:WP_032596671	DNA topoisomerase I, partial [Bacteroides fragilis].	31.30	377	226	12	60	430	142	491	2e-34	145
rs:WP_038653193	DNA topoisomerase I [Mucinivorans hirudinis].	32.84	335	193	10	60	384	264	576	2e-34	146
rs:WP_035290026	DNA topoisomerase III [Clostridium sp. KNHs214].	30.39	408	255	11	47	445	235	622	2e-34	146
rs:WP_006058367	DNA topoisomerase III [Holdemania filiformis].	31.65	395	243	11	40	425	229	605	2e-34	146
rs:WP_028408833	DNA topoisomerase [Bacillus sp. 171095_106].	30.32	409	240	14	59	450	271	651	2e-34	146
rs:WP_016316312	DNA topoisomerase III [Anaerotruncus sp. G3(2012)].	31.47	375	218	8	40	398	229	580	2e-34	145
rs:WP_038605799	DNA topoisomerase I [Bacteroides dorei].	30.29	373	238	10	59	427	259	613	2e-34	145
rs:WP_005800102	DNA topoisomerase I [Bacteroides fragilis].	30.23	387	253	10	43	427	246	617	2e-34	146
rs:WP_044230524	DNA topoisomerase I [Coprobacter sp. 177].	30.54	370	236	10	60	427	262	612	2e-34	145
rs:WP_035029208	DNA topoisomerase III [Carnobacterium mobile].	26.55	388	243	5	47	431	241	589	2e-34	145
rs:WP_040759101	DNA topoisomerase III, partial [Sporosarcina newyorkensis].	29.78	319	192	9	155	456	38	341	2e-34	143
rs:WP_002993293	DNA topoisomerase [Sphingobacterium spiritivorum].	30.77	338	220	8	48	382	250	576	2e-34	145
rs:WP_012344603	DNA topoisomerase III [Clostridium botulinum].	29.54	369	231	10	40	398	252	601	2e-34	145
rs:WP_032508493	DNA topoisomerase III, partial [Peptoclostridium difficile].	29.13	357	225	10	47	396	249	584	2e-34	145
tr:G4L3K7_TETHN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.82	323	199	7	52	368	264	574	2e-34	145
rs:WP_032596729	DNA topoisomerase I [Bacteroides fragilis].	32.10	324	200	8	57	377	259	565	3e-34	145
tr:A6E8D3_9SPHI	SubName: Full=Putative transposon excision protein {ECO:0000313|EMBL:EDM38263.1};	28.61	367	235	12	21	382	237	581	3e-34	145
rs:WP_029427001	DNA topoisomerase I [Bacteroides cellulosilyticus].	32.86	353	211	11	56	400	258	592	3e-34	145
rs:WP_021740058	DNA topoisomerase [Eubacterium ramulus].	28.57	371	239	9	51	397	278	646	3e-34	145
rs:WP_047927552	DNA topoisomerase III [Enterococcus faecium].	27.25	400	250	7	47	445	207	566	3e-34	145
rs:WP_022089074	DNA topoisomerase [Eubacterium sp. CAG:156].	28.44	429	250	14	24	401	249	671	3e-34	145
tr:L2QP66_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.25	400	250	7	47	445	207	566	3e-34	145
rs:WP_022272651	DNA topoisomerase III [Clostridium sp. CAG:58].	29.00	400	239	12	35	392	262	658	3e-34	145
rs:WP_008772022	DNA topoisomerase I [Bacteroides sp. 2_1_33B].	30.29	373	238	11	59	427	259	613	3e-34	145
rs:WP_008759619	DNA topoisomerase I [Bacteroides sp. 1_1_14].	31.56	377	224	11	60	430	263	611	3e-34	145
rs:WP_035055399	DNA topoisomerase III [Carnobacterium pleistocenium].	26.29	388	244	7	47	431	241	589	3e-34	145
tr:D4X879_9BURK	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:EFF77009.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFF77009.1};	37.90	219	130	2	190	406	242	456	3e-34	144
rs:WP_011222029	DNA topoisomerase [Lactobacillus plantarum].	31.07	354	213	10	56	397	268	602	3e-34	145
rs:WP_022784300	DNA topoisomerase III [Lachnospiraceae bacterium NK4A179].	28.61	423	233	13	47	422	272	672	3e-34	145
rs:WP_032572846	DNA topoisomerase I [Bacteroides fragilis].	32.10	324	200	8	57	377	259	565	3e-34	145
rs:WP_004310027	MULTISPECIES: DNA topoisomerase I [Bacteroides].	30.50	377	243	10	54	427	256	616	3e-34	145
rs:WP_047432776	DNA topoisomerase I [Chryseobacterium sp. YR477].	28.04	403	262	8	20	421	240	615	3e-34	145
tr:F9EMU8_FUSNU	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EGQ79718.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EGQ79718.1};	26.89	424	280	8	40	448	241	649	3e-34	145
rs:WP_039630371	DNA topoisomerase [Clostridium argentinense].	28.87	433	252	17	48	452	263	667	3e-34	146
rs:WP_002344553	DNA topoisomerase III, partial [Enterococcus faecium].	27.25	400	250	8	47	445	207	566	3e-34	145
tr:D4VW42_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.25	400	250	8	47	445	207	566	3e-34	145
rs:WP_016728792	DNA topoisomerase [Peptoclostridium difficile].	29.13	357	225	10	47	396	249	584	3e-34	146
rs:WP_016112277	DNA topoisomerase 1 [Bacillus cereus].	25.94	424	297	9	35	454	239	649	3e-34	147
rs:WP_010297015	DNA topoisomerase III [Clostridium senegalense].	29.68	374	227	11	40	398	252	604	3e-34	144
rs:WP_021646279	DNA topoisomerase [Bacteroides pyogenes].	29.97	387	254	11	43	427	246	617	3e-34	145
rs:WP_022495166	DNA topoisomerase [Ruminococcus sp. CAG:624].	27.95	415	267	13	38	446	242	630	3e-34	145
rs:WP_005213949	DNA topoisomerase [Clostridium celatum].	29.27	427	252	16	48	452	261	659	3e-34	145
rs:WP_033627655	DNA topoisomerase III [Enterococcus faecium].	27.25	400	250	7	47	445	241	600	3e-34	145
rs:WP_022150917	DNA topoisomerase III [Lachnospiraceae bacterium CAG:215].	30.18	391	225	13	47	392	271	658	3e-34	145
rs:WP_008653364	DNA topoisomerase I [Bacteroides sp. 3_1_33FAA].	31.30	377	226	12	60	430	263	612	3e-34	145
rs:WP_002358501	DNA topoisomerase, partial [Enterococcus faecium].	34.42	276	166	6	93	365	8	271	3e-34	141
rs:WP_010232935	DNA topoisomerase [Clostridium arbusti].	28.57	420	256	14	43	446	256	647	3e-34	145
rs:WP_007287786	DNA topoisomerase III [Intestinibacter bartlettii].	27.93	444	252	15	47	450	249	664	3e-34	145
tr:C2XKX2_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.76	426	291	10	35	454	246	656	3e-34	146
rs:WP_031875871	DNA topoisomerase III, partial [Staphylococcus aureus].	30.54	298	186	7	155	450	14	292	3e-34	142
rs:WP_031922615	DNA topoisomerase III [Staphylococcus aureus].	27.61	402	264	10	57	454	268	646	4e-34	145
rs:WP_045216857	hypothetical protein, partial [Desulfobulbus alkaliphilus].	29.95	364	211	8	47	387	253	595	4e-34	144
rs:WP_016078683	DNA topoisomerase 1 [Bacillus cereus].	26.65	424	294	9	35	454	239	649	4e-34	146
rs:WP_000520731	DNA topoisomerase I [Bacillus cereus].	26.76	426	291	10	35	454	239	649	4e-34	146
rs:WP_032559152	DNA topoisomerase I [Bacteroides fragilis].	29.49	373	241	10	59	427	259	613	4e-34	145
rs:WP_032572212	DNA topoisomerase I [Bacteroides fragilis].	29.49	373	241	10	59	427	259	613	4e-34	145
rs:WP_022140739	DNA topoisomerase III [Clostridium sp. CAG:230].	31.41	347	214	10	72	396	329	673	4e-34	145
rs:WP_025434990	DNA topoisomerase III [Eubacterium acidaminophilum].	31.31	428	247	16	37	449	225	620	4e-34	145
rs:WP_027702382	DNA topoisomerase [[Clostridium] mangenotii].	30.47	361	215	12	47	396	248	583	4e-34	145
rs:WP_021413190	DNA topoisomerase III, partial [Peptoclostridium difficile].	29.13	357	225	10	47	396	249	584	4e-34	145
tr:R2QYG4_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.62	282	174	6	77	354	2	271	4e-34	140
rs:WP_044798480	DNA topoisomerase I, partial [Bacillus thuringiensis].	26.42	424	295	9	35	454	239	649	4e-34	145
rs:WP_026694892	DNA topoisomerase [Bacillus kribbensis].	30.05	396	243	11	65	450	278	649	4e-34	145
rs:WP_008016669	DNA topoisomerase, partial [Bacteroides xylanisolvens].	30.29	373	238	11	59	427	231	585	4e-34	145
rs:WP_025022469	DNA topoisomerase III [Lactobacillus hayakitensis].	28.86	402	240	10	47	445	241	599	4e-34	145
rs:WP_029505782	DNA topoisomerase III [Lachnospiraceae bacterium AC2012].	31.18	372	192	15	72	399	315	666	4e-34	145
rs:WP_002340969	DNA topoisomerase III, partial [Enterococcus faecium].	27.25	400	250	8	47	445	207	566	4e-34	145
rs:WP_013634106	DNA topoisomerase III [Pseudopedobacter saltans].	30.86	337	207	12	56	382	262	582	4e-34	144
rs:WP_022203700	DNA topoisomerase [Eubacterium sp. CAG:248].	29.54	369	220	11	59	392	286	649	4e-34	145
rs:WP_039866065	DNA topoisomerase I, partial [Pedobacter sp. BAL39].	28.61	367	235	12	21	382	237	581	4e-34	144
rs:WP_040955857	DNA topoisomerase [Virgibacillus sp. SK37].	28.64	426	266	14	36	450	249	647	4e-34	145
rs:WP_019376132	hypothetical protein [Virgibacillus halodenitrificans].	29.38	422	264	13	38	450	251	647	4e-34	145
tr:K0B0G9_CLOA9	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.58	355	212	11	72	399	305	648	4e-34	145
rs:WP_007366532	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	29.65	371	234	9	60	427	263	609	4e-34	145
rs:WP_008752394	DNA topoisomerase III [Lachnoanaerobaculum saburreum].	33.15	368	217	12	37	398	225	569	4e-34	144
rs:WP_021413946	DNA topoisomerase [Peptoclostridium difficile].	29.13	357	225	10	47	396	249	584	4e-34	145
rs:WP_025078801	DNA topoisomerase I [Prevotella fusca].	28.85	409	265	10	22	425	221	608	4e-34	145
rs:WP_009090442	DNA topoisomerase [Elizabethkingia anophelis].	25.93	428	287	11	24	446	216	618	4e-34	145
rs:WP_008689666	DNA topoisomerase III [Eubacterium sp. 3_1_31].	31.07	338	216	7	66	397	256	582	4e-34	145
tr:B7BDS6_9PORP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.67	388	243	12	43	427	72	436	4e-34	144
rs:WP_022076405	DNA topoisomerase III [Firmicutes bacterium CAG:212].	31.09	341	213	10	72	392	299	637	4e-34	145
tr:K8B7E1_9ENTR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CCJ84182.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CCJ84182.1};	37.07	205	123	1	181	385	2	200	4e-34	139
rs:WP_022036564	hypothetical protein [Roseburia sp. CAG:50].	28.57	371	239	9	51	397	278	646	4e-34	145
rs:WP_036633291	hypothetical protein, partial [Paenibacillus alginolyticus].	30.00	350	240	5	40	385	249	597	4e-34	146
rs:WP_031557102	DNA topoisomerase III [Lachnospiraceae bacterium FD2005].	31.18	372	192	15	72	399	315	666	4e-34	145
rs:WP_003035804	DNA topoisomerase III [Streptococcus anginosus].	32.87	362	216	10	40	398	230	567	4e-34	144
rs:WP_047660481	DNA topoisomerase III, partial [Escherichia coli].	30.88	285	178	5	172	443	1	279	4e-34	141
rs:WP_004342576	DNA topoisomerase I [Prevotella buccae].	28.90	429	258	11	3	425	221	608	4e-34	145
rs:WP_016271901	DNA topoisomerase III [Bacteroides vulgatus].	31.56	377	225	12	60	430	263	612	4e-34	145
rs:WP_027433226	DNA topoisomerase III [Lachnospiraceae bacterium MD2004].	31.18	372	192	15	72	399	315	666	4e-34	145
rs:WP_002561001	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	31.56	377	224	11	60	430	263	611	4e-34	145
rs:WP_035620641	DNA topoisomerase I [Flavobacterium hydatis].	28.70	345	235	5	48	391	250	584	4e-34	145
rs:WP_022618531	DNA topoisomerase type IA [Peptoclostridium difficile].	29.13	357	225	10	47	396	249	584	4e-34	145
rs:WP_003430842	DNA topoisomerase [Peptoclostridium difficile].	29.13	357	225	10	47	396	249	584	5e-34	145
rs:WP_002313368	DNA topoisomerase III [Enterococcus faecium].	26.75	400	252	8	47	445	241	600	5e-34	145
rs:WP_008777471	DNA topoisomerase I [Bacteroides sp. 2_2_4].	30.50	377	243	10	54	427	256	616	5e-34	145
rs:WP_041701982	DNA topoisomerase III [Gottschalkia acidurici].	29.58	355	212	11	72	399	301	644	5e-34	145
rs:WP_019131012	DNA topoisomerase I [Bacteroidales bacterium ph8].	31.56	377	224	11	60	430	263	611	5e-34	145
rs:WP_016306102	hypothetical protein [Lachnospiraceae bacterium A2].	29.97	397	227	15	49	397	298	691	5e-34	145
rs:WP_034468441	hypothetical protein, partial [Butyrivibrio sp. AE2005].	29.95	434	231	16	22	400	245	660	5e-34	145
rs:WP_034462255	hypothetical protein, partial [Butyrivibrio sp. AE3003].	29.95	434	231	16	22	400	245	660	5e-34	145
rs:WP_024635340	DNA topoisomerase III, partial [Enterococcus faecium].	27.25	400	250	8	47	445	207	566	5e-34	144
rs:WP_010763001	DNA topoisomerase III [Enterococcus haemoperoxidus].	27.25	400	250	8	47	445	243	602	5e-34	145
rs:WP_025477199	DNA topoisomerase III, partial [Enterococcus faecium].	27.25	400	250	8	47	445	207	566	5e-34	144
tr:E0NQU0_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFM02460.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFM02460.1};	31.56	377	224	11	60	430	282	630	5e-34	145
rs:WP_009897597	DNA topoisomerase [Peptoclostridium difficile].	29.13	357	225	10	47	396	249	584	5e-34	145
rs:WP_010771366	DNA topoisomerase III [Enterococcus caccae].	27.25	400	250	8	47	445	243	602	5e-34	145
rs:WP_009296552	DNA topoisomerase III [Clostridium sp. 7_3_54FAA].	30.53	357	231	7	47	397	237	582	5e-34	145
rs:WP_034500952	hypothetical protein, partial [Butyrivibrio hungatei].	29.95	434	231	16	22	400	245	660	5e-34	145
rs:WP_032131825	DNA topoisomerase I [Weeksella sp. FF8].	29.57	345	232	5	48	391	250	584	5e-34	145
rs:WP_024990781	DNA topoisomerase I [Prevotella marshii].	31.56	377	224	11	60	430	263	611	5e-34	145
rs:WP_018709306	DNA topoisomerase I [Bacteroides barnesiae].	31.98	344	210	10	60	393	264	593	5e-34	145
rs:WP_009893600	DNA topoisomerase [Peptoclostridium difficile].	29.13	357	225	10	47	396	249	584	5e-34	145
tr:A0A090SK27_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL27228.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL27228.1};	36.10	205	125	1	200	404	2	200	5e-34	138
rs:WP_004454701	DNA topoisomerase [Peptoclostridium difficile].	29.13	357	225	10	47	396	249	584	5e-34	145
rs:WP_021425657	DNA topoisomerase [Peptoclostridium difficile].	29.13	357	225	10	47	396	249	584	5e-34	145
rs:WP_004329672	DNA topoisomerase I [Alistipes putredinis].	30.21	374	237	12	59	427	259	613	5e-34	145
rs:WP_011861544	DNA topoisomerase [Peptoclostridium difficile].	29.13	357	225	10	47	396	249	584	5e-34	145
rs:WP_004313263	DNA topoisomerase I [Bacteroides xylanisolvens].	30.29	373	238	11	59	427	259	613	5e-34	145
rs:WP_047338624	DNA topoisomerase III [Enterococcus cecorum].	26.10	387	246	6	47	431	241	589	5e-34	145
tr:D6DKA4_CLOSC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.88	434	265	13	3	392	228	657	5e-34	145
rs:WP_042994626	DNA topoisomerase I [Bacteroides fragilis].	30.50	377	243	10	54	427	256	616	5e-34	145
rs:WP_021421652	DNA topoisomerase [Peptoclostridium difficile].	29.13	357	225	10	47	396	249	584	5e-34	145
rs:WP_031885094	DNA topoisomerase III [Staphylococcus aureus].	28.16	419	265	13	41	454	259	646	5e-34	145
rs:WP_036764085	DNA topoisomerase [Peptostreptococcus sp. MV1].	26.70	382	257	7	26	402	228	591	5e-34	145
rs:WP_032495452	DNA topoisomerase, partial [Enterococcus thailandicus].	32.66	297	172	8	169	452	1	282	5e-34	140
rs:WP_015695070	DNA topoisomerase III [Melissococcus plutonius].	27.18	401	249	8	47	445	243	602	6e-34	145
tr:D4QJS4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.00	400	251	7	47	445	207	566	6e-34	144
rs:WP_021422494	DNA topoisomerase [Peptoclostridium difficile].	29.13	357	225	10	47	396	249	584	6e-34	145
rs:WP_006780354	DNA topoisomerase III [Hungatella hathewayi].	28.72	390	229	11	50	392	277	664	6e-34	145
rs:WP_032586196	DNA topoisomerase I [Bacteroides fragilis].	31.56	377	224	11	60	430	263	611	6e-34	145
rs:WP_032889348	DNA topoisomerase [Fusobacterium nucleatum].	26.67	405	267	8	40	426	236	628	6e-34	145
rs:WP_044166537	DNA topoisomerase III, partial [Staphylococcus aureus].	30.43	299	187	7	154	450	2	281	6e-34	141
rs:WP_014012324	DNA topoisomerase I [Thermococcus sp. 4557].	27.59	464	257	12	40	457	246	676	6e-34	145
rs:WP_012571272	DNA topoisomerase I [Thermococcus onnurineus].	29.70	468	245	18	40	459	246	677	6e-34	145
rs:WP_005650116	DNA topoisomerase I [Parabacteroides merdae].	31.98	344	210	10	60	393	264	593	6e-34	145
rs:WP_025491694	DNA topoisomerase III [Clostridiales bacterium VE202-27].	29.80	349	234	5	47	393	237	576	6e-34	144
rs:WP_016099670	DNA topoisomerase III [Bacillus cereus].	27.78	396	245	11	67	450	278	644	6e-34	145
rs:WP_031884499	DNA topoisomerase III, partial [Staphylococcus aureus].	27.05	403	265	11	57	454	19	397	6e-34	142
rs:WP_006801223	DNA topoisomerase I [Dysgonomonas gadei].	31.03	319	208	8	61	377	263	571	6e-34	144
rs:WP_002502793	DNA topoisomerase [Staphylococcus epidermidis].	29.63	405	248	11	56	444	273	656	6e-34	145
tr:A0A0F5J6J7_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KKB53090.1};	29.67	418	260	12	22	427	209	604	6e-34	144
rs:WP_005680447	DNA topoisomerase I [Bacteroides caccae].	30.59	376	244	10	54	427	256	616	6e-34	144
rs:WP_038611241	DNA topoisomerase I [Bacteroides dorei].	30.56	373	237	11	59	427	259	613	6e-34	144
rs:WP_010801747	MULTISPECIES: DNA topoisomerase III [Bacteroidales].	31.56	377	225	12	60	430	263	612	6e-34	144
tr:J6Y259_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.25	400	250	8	47	445	223	582	6e-34	144
rs:WP_025478548	DNA topoisomerase III, partial [Enterococcus faecium].	27.25	400	250	8	47	445	207	566	6e-34	144
rs:WP_022201940	DNA topoisomerase III [Clostridium clostridioforme CAG:132].	28.22	404	233	13	43	392	272	672	6e-34	144
rs:WP_002351500	DNA topoisomerase, partial [Enterococcus faecium].	32.87	289	172	7	151	427	15	293	6e-34	139
rs:WP_037593321	DNA topoisomerase III, partial [Sporosarcina sp. D27].	30.16	378	214	16	102	454	7	359	6e-34	142
rs:WP_032558364	DNA topoisomerase I [Bacteroides fragilis].	29.49	373	241	10	59	427	259	613	6e-34	144
tr:A0A011QH80_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.47	293	160	8	40	314	255	533	6e-34	143
rs:WP_005364064	DNA topoisomerase III [Eubacterium ventriosum].	28.84	430	244	15	35	405	259	685	6e-34	144
tr:C9AL42_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.25	400	250	8	47	445	241	600	7e-34	144
rs:WP_042680133	DNA topoisomerase I [Thermococcus paralvinellae].	28.30	470	251	13	40	457	246	681	7e-34	145
tr:R9HPA4_BACUN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOS05606.1};	29.22	373	242	9	59	427	127	481	7e-34	143
rs:WP_032581312	DNA topoisomerase I [Bacteroides fragilis].	30.36	359	230	9	71	427	273	613	7e-34	144
rs:WP_002583310	DNA topoisomerase III [[Clostridium] clostridioforme].	28.22	404	233	13	43	392	272	672	7e-34	144
rs:WP_020805409	DNA topoisomerase, partial [Klebsiella pneumoniae].	38.78	196	116	2	40	233	2	195	7e-34	137
rs:WP_014072880	DNA topoisomerase III [Lactobacillus ruminis].	27.27	385	243	6	47	431	241	588	7e-34	144
rs:WP_016304287	DNA topoisomerase III [Lachnospiraceae bacterium A2].	30.95	391	249	10	43	426	230	606	7e-34	144
tr:F0HU31_LACDL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.22	295	179	6	57	347	269	549	7e-34	143
rs:WP_032133432	DNA topoisomerase III [Kingella kingae].	27.79	421	258	10	43	431	231	637	7e-34	144
rs:WP_046148757	DNA topoisomerase I [Parabacteroides sp. HGS0025].	29.67	418	260	12	22	427	221	616	7e-34	144
rs:WP_039076293	DNA topoisomerase III [Bacillus sp. MSP13].	28.72	397	222	11	67	446	265	617	7e-34	144
rs:WP_021406476	DNA topoisomerase [Peptoclostridium difficile].	29.13	357	225	10	47	396	249	584	7e-34	145
rs:WP_010731992	DNA topoisomerase III [Enterococcus faecium].	27.25	400	250	8	47	445	207	566	7e-34	144
rs:WP_034491856	DNA topoisomerase III, partial [Butyrivibrio fibrisolvens].	28.01	432	241	14	17	392	244	661	7e-34	144
rs:WP_031879283	DNA topoisomerase III, partial [Staphylococcus aureus].	26.59	425	281	12	35	454	10	408	7e-34	142
rs:WP_025082441	DNA topoisomerase III [Lactobacillus fuchuensis].	27.99	368	233	3	35	402	230	565	8e-34	144
rs:WP_007754171	MULTISPECIES: DNA topoisomerase I [Bacteroides].	30.36	359	230	9	71	427	273	613	8e-34	144
rs:WP_034490071	DNA topoisomerase III [Butyrivibrio fibrisolvens].	28.67	443	243	16	17	400	244	672	8e-34	144
rs:WP_032494930	DNA topoisomerase [Enterococcus faecium].	33.56	289	180	5	54	339	295	574	8e-34	143
tr:C0D086_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.05	406	234	13	35	392	267	670	8e-34	144
rs:WP_018704325	MULTISPECIES: hypothetical protein [Veillonellaceae].	29.70	404	246	11	61	452	275	652	8e-34	144
rs:WP_035458144	hypothetical protein, partial [Bacteroides uniformis].	29.22	373	242	9	59	427	128	482	8e-34	143
rs:WP_003416718	DNA topoisomerase [Peptoclostridium difficile].	29.13	357	225	10	47	396	249	584	8e-34	145
rs:WP_047797752	DNA topoisomerase I [Pedobacter sp. BMA].	30.06	346	219	11	47	382	249	581	8e-34	143
rs:WP_024564660	MULTISPECIES: DNA topoisomerase I [Elizabethkingia].	28.41	345	236	5	48	391	250	584	8e-34	144
rs:WP_004335184	DNA topoisomerase I [Porphyromonas endodontalis].	28.57	413	263	12	22	426	221	609	8e-34	144
tr:L2R3E3_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.25	400	250	8	47	445	207	566	8e-34	144
rs:WP_031921854	DNA topoisomerase III, partial [Staphylococcus aureus].	27.05	403	265	11	57	454	20	398	8e-34	142
rs:WP_009291857	DNA topoisomerase I [Bacteroides sp. 2_1_56FAA].	29.81	359	232	8	71	427	273	613	8e-34	144
rs:WP_021953303	DNA topoisomerase [Eubacterium sp. CAG:161].	28.97	428	241	15	35	405	260	681	8e-34	144
rs:WP_032569621	DNA topoisomerase I [Bacteroides fragilis].	29.49	373	241	10	59	427	259	613	8e-34	144
rs:WP_026513782	DNA topoisomerase III [Butyrivibrio sp. LB2008].	30.09	432	233	17	22	400	245	660	8e-34	144
rs:WP_033583050	DNA topoisomerase III [Enterococcus faecium].	27.00	400	251	7	47	445	241	600	8e-34	144
rs:WP_022752908	DNA topoisomerase III [Butyrivibrio fibrisolvens].	28.67	443	243	16	17	400	244	672	9e-34	144
rs:WP_002326518	DNA topoisomerase III [Enterococcus faecium].	30.50	341	223	6	57	392	268	599	9e-34	144
rs:WP_034638122	DNA topoisomerase [Bacillus manliponensis].	27.63	427	267	14	36	450	249	645	9e-34	144
rs:WP_029321285	DNA topoisomerase [Bacillus sp. RP1137].	30.07	409	245	14	57	450	269	651	9e-34	144
rs:WP_021885805	DNA topoisomerase [Clostridium sp. CAG:590].	31.07	338	215	11	74	395	309	644	9e-34	144
rs:WP_009093060	DNA topoisomerase [Elizabethkingia anophelis].	25.93	428	287	11	24	446	216	618	9e-34	144
rs:WP_005867781	DNA topoisomerase I [Parabacteroides distasonis].	30.81	370	231	10	60	427	263	609	9e-34	144
tr:H8LFB1_ENTFU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.79	341	222	6	57	392	269	600	9e-34	144
rs:WP_044031624	DNA topoisomerase [Enterococcus faecium].	30.79	341	222	6	57	392	268	599	9e-34	144
rs:WP_004294818	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	29.49	373	241	10	59	427	259	613	9e-34	144
tr:A0A0B5HG25_9ARCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.96	443	282	12	22	454	221	627	9e-34	144
rs:WP_042396023	DNA topoisomerase [Clostridium sp. JCC].	28.24	432	253	14	48	452	261	662	9e-34	144
rs:WP_038328472	DNA topoisomerase III [Kingella kingae].	27.85	395	241	10	70	432	200	582	9e-34	144
rs:WP_003210143	DNA topoisomerase [Bacillus mycoides].	27.70	426	268	13	36	450	249	645	1e-33	144
rs:WP_002345924	DNA topoisomerase III [Enterococcus faecium].	28.29	403	264	9	44	437	256	642	1e-33	144
rs:WP_034484200	DNA topoisomerase III, partial [Butyrivibrio fibrisolvens].	28.70	432	238	15	17	392	244	661	1e-33	144
rs:WP_044111880	hypothetical protein [Porphyromonas uenonis].	28.92	370	247	9	41	406	248	605	1e-33	144
rs:WP_044906266	hypothetical protein, partial [Lachnospiraceae bacterium MC2017].	27.85	377	233	7	59	399	292	665	1e-33	144
tr:A0A0D6A520_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.57	280	167	7	56	330	10	275	1e-33	138
rs:WP_021426560	DNA topoisomerase [Peptoclostridium difficile].	29.13	357	225	10	47	396	249	584	1e-33	144
rs:WP_041487960	DNA topoisomerase III, partial [Bacillus thuringiensis].	32.18	289	182	6	36	321	244	521	1e-33	142
rs:WP_036930050	DNA topoisomerase I [Prevotella timonensis].	30.59	376	230	10	60	430	263	612	1e-33	144
rs:WP_021628044	DNA topoisomerase, partial [Capnocytophaga sp. oral taxon 863].	30.96	365	229	14	39	391	150	503	1e-33	142
rs:WP_040411739	DNA topoisomerase III [[Clostridium] asparagiforme].	30.05	406	234	13	35	392	263	666	1e-33	144
rs:WP_047656814	DNA topoisomerase III, partial [Salmonella enterica].	41.82	165	94	2	36	200	251	413	1e-33	141
rs:WP_010601443	DNA topoisomerase type IA central domain-containing protein, partial [Pedobacter agri].	30.42	332	206	13	59	382	115	429	1e-33	142
rs:WP_009324599	DNA topoisomerase III [Subdoligranulum sp. 4_3_54A2FAA].	31.07	338	216	7	66	397	256	582	1e-33	144
rs:WP_036927629	DNA topoisomerase I, partial [Prevotella timonensis].	30.81	357	220	9	74	426	284	617	1e-33	144
rs:WP_025731506	DNA topoisomerase III [Bacillus ginsengihumi].	29.59	392	227	15	77	452	280	638	1e-33	144
tr:A0A0D0I5N4_BACTM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.18	289	182	6	36	321	244	521	1e-33	142
tr:A9KSH4_CLOPH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.60	375	217	11	61	392	322	692	1e-33	144
tr:C3DIJ7_BACTS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.18	289	182	6	36	321	244	521	1e-33	142
rs:WP_031834529	DNA topoisomerase III, partial [Staphylococcus aureus].	26.62	402	268	10	57	454	69	447	1e-33	142
rs:WP_003445085	DNA topoisomerase III [Clostridium pasteurianum].	31.97	366	207	14	54	406	266	602	1e-33	143
rs:WP_022757070	DNA topoisomerase III [Butyrivibrio fibrisolvens].	28.67	443	243	16	17	400	244	672	1e-33	144
rs:WP_041703756	DNA topoisomerase III [Lachnoclostridium phytofermentans].	29.60	375	217	11	61	392	316	686	1e-33	144
sp:TOP1_BACPE	RecName: Full=DNA topoisomerase 1; EC=5.99.1.2; AltName: Full=DNA topoisomerase I; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	28.27	421	270	12	36	446	247	645	1e-33	144
rs:WP_032587146	DNA topoisomerase I [Bacteroides fragilis].	31.03	377	227	12	60	430	263	612	1e-33	144
rs:WP_042597590	DNA topoisomerase [Bacillus thuringiensis].	28.04	428	264	15	36	450	249	645	1e-33	144
rs:WP_002561265	DNA topoisomerase III [Bacteroides sp. HPS0048].	29.67	418	260	12	22	427	221	616	1e-33	144
rs:WP_044931349	DNA topoisomerase III [Clostridium sp. M62/1].	27.88	434	265	13	3	392	228	657	1e-33	144
rs:WP_036894232	DNA topoisomerase I [Prevotella sp. S7-1-8].	31.37	357	218	9	74	426	284	617	1e-33	144
rs:WP_012679621	DNA topoisomerase III [Streptococcus equi].	32.88	365	218	10	37	398	226	566	1e-33	142
rs:WP_035649896	DNA topoisomerase I [Flavobacterium sp. Fl].	29.28	345	233	5	48	391	250	584	1e-33	144
tr:J8WAQ0_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.75	400	252	8	47	445	223	582	1e-33	143
rs:WP_034549119	DNA topoisomerase III [Carnobacterium alterfunditum].	25.65	386	249	5	47	431	241	589	1e-33	144
tr:A0A097QU60_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.23	464	253	14	40	457	246	675	1e-33	144
rs:WP_031921633	DNA topoisomerase III, partial [Staphylococcus aureus].	27.46	386	251	11	74	454	4	365	1e-33	140
rs:WP_022026173	DNA topoisomerase III [Clostridium sp. CAG:75].	29.77	383	231	12	47	393	273	653	1e-33	143
rs:WP_031861664	DNA topoisomerase III [Staphylococcus aureus].	26.42	424	283	11	35	454	248	646	1e-33	144
rs:WP_019393159	MULTISPECIES: DNA topoisomerase [Bacillus].	29.68	411	248	14	54	450	266	649	1e-33	144
rs:WP_031471795	DNA topoisomerase III, partial [[Clostridium] aminophilum].	30.43	391	222	13	57	399	289	677	1e-33	143
tr:V2BSP1_SALDE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESH31240.1};	37.06	197	118	1	189	385	1	191	1e-33	137
rs:WP_044960508	DNA topoisomerase III [Faecalibacterium prausnitzii].	28.94	425	263	12	34	447	57	453	1e-33	142
rs:WP_031903950	DNA topoisomerase III, partial [Staphylococcus aureus].	26.18	424	284	11	35	454	92	490	1e-33	142
rs:WP_025479193	DNA topoisomerase, partial [Enterococcus faecium].	33.57	286	174	6	57	337	268	542	1e-33	142
rs:WP_008782576	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	31.30	377	226	12	60	430	263	612	1e-33	144
rs:WP_003509283	DNA topoisomerase III [[Clostridium] symbiosum].	31.07	338	216	7	66	397	256	582	1e-33	144
rs:WP_034697924	DNA topoisomerase [Enterococcus hirae].	29.74	343	220	7	57	392	269	597	1e-33	144
rs:WP_007366263	DNA topoisomerase III [Porphyromonas uenonis].	29.60	375	240	10	41	407	248	606	1e-33	144
rs:WP_042598621	DNA topoisomerase III, partial [Bacillus thuringiensis].	32.18	289	182	6	36	321	244	521	1e-33	142
rs:WP_002308233	DNA topoisomerase III [Enterococcus faecium].	26.75	400	252	8	47	445	241	600	1e-33	143
rs:WP_048165136	DNA topoisomerase I [Palaeococcus pacificus].	28.88	464	251	14	40	457	246	676	1e-33	144
rs:WP_002980964	DNA topoisomerase [Chryseobacterium gleum].	27.97	404	261	9	20	421	240	615	1e-33	144
rs:WP_047213735	DNA topoisomerase III, partial [Staphylococcus aureus].	30.20	298	187	7	155	450	33	311	1e-33	140
tr:A8SC99_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.94	425	263	12	34	447	138	534	1e-33	142
rs:WP_036059528	hypothetical protein [Listeria weihenstephanensis].	28.93	401	242	11	69	451	255	630	1e-33	143
rs:WP_033643474	DNA topoisomerase III [Enterococcus faecium].	27.25	400	250	8	47	445	241	600	1e-33	143
rs:WP_004606705	DNA topoisomerase III [[Clostridium] scindens].	30.50	341	215	9	72	392	299	637	1e-33	143
rs:WP_040600277	hypothetical protein, partial [Sphingobium ummariense].	30.72	332	208	9	69	387	265	587	1e-33	143
rs:WP_042275571	DNA topoisomerase [Clostridium sp. 01].	29.13	357	225	10	47	396	249	584	1e-33	144
rs:WP_002329557	DNA topoisomerase III, partial [Enterococcus faecium].	27.00	400	251	8	47	445	207	566	1e-33	143
rs:WP_009016629	DNA topoisomerase I [Parabacteroides sp. D13].	29.73	370	235	9	60	427	263	609	2e-33	143
tr:T0IXR4_9SPHN	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.72	332	208	9	69	387	265	587	2e-33	143
rs:WP_002597132	hypothetical protein [Clostridium colicanis].	29.52	437	242	17	49	452	150	553	2e-33	142
rs:WP_007845711	DNA topoisomerase I [Bacteroides dorei].	30.36	359	230	9	71	427	273	613	2e-33	143
rs:WP_042853364	DNA topoisomerase III, partial [Staphylococcus aureus].	27.46	386	251	11	74	454	4	365	2e-33	140
rs:WP_044798418	DNA topoisomerase I [Bacillus thuringiensis].	26.73	419	290	9	35	449	239	644	2e-33	144
rs:WP_016421320	DNA topoisomerase III [Capnocytophaga granulosa].	31.23	365	228	14	39	391	240	593	2e-33	143
rs:WP_034053622	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	36.27	204	128	1	205	406	2	205	2e-33	136
rs:WP_026667054	MULTISPECIES: DNA topoisomerase III [Butyrivibrio].	30.03	373	243	7	57	425	247	605	2e-33	143
tr:W6UCE3_9SPHI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.31	348	231	10	59	402	267	603	2e-33	142
rs:WP_034486619	DNA topoisomerase III [Butyrivibrio fibrisolvens].	27.99	443	246	15	17	400	244	672	2e-33	143
rs:WP_044909883	DNA topoisomerase III [Lachnospiraceae bacterium MC2017].	29.02	441	268	15	27	445	214	631	2e-33	143
rs:WP_020999685	DNA topoisomerase III [Streptococcus anginosus].	32.60	362	217	10	40	398	230	567	2e-33	142
rs:WP_022020959	DNA topoisomerase [Bacteroides sp. CAG:661].	31.03	390	234	11	20	393	223	593	2e-33	143
rs:WP_010782941	DNA topoisomerase III, partial [Enterococcus faecalis].	26.11	429	288	11	30	454	127	530	2e-33	142
rs:WP_002448594	DNA topoisomerase III [Staphylococcus hominis].	24.53	424	286	8	35	449	227	625	2e-33	143
tr:R9X141_LACPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.25	320	191	8	89	397	4	305	2e-33	140
rs:WP_031825716	DNA topoisomerase III, partial [Staphylococcus aureus].	26.18	424	284	11	35	454	180	578	2e-33	142
rs:WP_048176144	DNA topoisomerase I [Methanothermobacter sp. CaT2].	27.49	451	276	12	18	458	219	628	2e-33	143
tr:D4CEE7_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.88	434	265	13	3	392	243	672	2e-33	144
rs:WP_031786070	DNA topoisomerase III, partial [Staphylococcus aureus].	26.18	424	284	11	35	454	209	607	2e-33	142
tr:R4EG70_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.50	400	253	7	47	445	207	566	2e-33	142
rs:WP_006845464	DNA topoisomerase [Weissella koreensis].	29.27	410	250	16	66	454	287	677	2e-33	143
rs:WP_044931597	hypothetical protein, partial [Butyrivibrio sp. AC2005].	31.83	355	214	14	41	379	273	615	2e-33	143
rs:WP_016270792	DNA topoisomerase III [Bacteroides vulgatus].	31.93	332	216	8	56	385	258	581	2e-33	143
rs:WP_011988545	DNA topoisomerase III [Yersinia pseudotuberculosis].	29.09	385	230	12	25	385	243	608	2e-33	144
tr:T4J8S2_PEPDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.50	400	253	7	47	445	193	552	2e-33	142
rs:WP_021630736	DNA topoisomerase [Clostridium sp. ATCC BAA-442].	30.30	406	237	13	52	445	241	612	2e-33	143
rs:WP_016295429	DNA topoisomerase III [Lachnospiraceae bacterium M18-1].	30.22	407	255	11	47	445	234	619	2e-33	143
rs:WP_022072193	DNA topoisomerase III [Clostridium bartlettii CAG:1329].	27.93	444	252	15	47	450	249	664	2e-33	143
rs:WP_016214645	DNA topoisomerase III [Eubacterium sp. 14-2].	31.45	372	213	15	62	395	301	668	2e-33	143
tr:A0A0F5IYV5_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KKB50375.1};	29.76	373	240	10	59	427	249	603	2e-33	143
rs:WP_029657514	DNA topoisomerase III, partial [Staphylococcus aureus].	26.18	424	284	11	35	454	219	617	2e-33	142
rs:WP_005816781	DNA topoisomerase I [Bacteroides fragilis].	31.30	377	226	12	60	430	263	612	2e-33	143
rs:WP_038303891	DNA topoisomerase III [Kingella kingae].	27.85	395	241	10	70	432	258	640	2e-33	143
rs:WP_021003063	DNA topoisomerase III [Streptococcus intermedius].	33.23	334	197	9	66	396	253	563	2e-33	142
rs:WP_032560966	DNA topoisomerase I [Bacteroides fragilis].	30.29	373	238	11	59	427	259	613	2e-33	143
tr:D3LED0_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.75	400	252	7	47	445	207	566	2e-33	142
rs:WP_044132082	DNA topoisomerase I [Bacteroides fragilis].	30.24	377	244	10	54	427	256	616	2e-33	143
tr:C9AEQ4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.04	403	265	9	44	437	186	572	2e-33	142
rs:WP_010737556	MULTISPECIES: DNA topoisomerase [Enterococcus].	29.74	343	220	7	57	392	269	597	2e-33	143
rs:WP_032585083	MULTISPECIES: DNA topoisomerase I [Bacteroides].	31.93	332	216	8	56	385	258	581	2e-33	143
rs:WP_037328208	DNA topoisomerase [Anaerococcus lactolyticus].	32.05	365	221	11	37	398	227	567	2e-33	142
rs:WP_003696757	DNA topoisomerase III [Lactobacillus ruminis].	26.67	405	258	8	41	445	235	600	2e-33	143
tr:L2JGT7_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.75	400	252	7	47	445	207	566	2e-33	142
rs:WP_004309983	DNA topoisomerase I [Bacteroides ovatus].	30.08	359	231	8	71	427	273	613	2e-33	143
rs:WP_031811082	DNA topoisomerase III, partial [Staphylococcus aureus].	26.62	402	268	10	57	454	174	552	2e-33	142
rs:WP_031833160	DNA topoisomerase III, partial [Staphylococcus aureus].	26.18	424	284	11	35	454	239	637	2e-33	142
rs:WP_002317775	DNA topoisomerase III [Enterococcus faecium].	26.75	400	252	7	47	445	241	600	2e-33	142
tr:C9BBV7_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.04	403	265	9	44	437	186	572	3e-33	142
rs:WP_033624242	DNA topoisomerase III [Enterococcus faecium].	26.50	400	253	7	47	445	241	600	3e-33	142
rs:WP_005421647	hypothetical protein [[Ruminococcus] obeum].	30.84	347	222	7	47	386	237	572	3e-33	143
rs:WP_016276248	DNA topoisomerase III, partial [Bacteroides massiliensis].	29.60	375	241	11	56	427	78	432	3e-33	141
rs:WP_033652941	DNA topoisomerase III [Enterococcus faecium].	26.50	400	253	7	47	445	241	600	3e-33	142
rs:WP_041100934	DNA topoisomerase [Bacillus badius].	30.14	418	243	14	53	450	265	653	3e-33	143
rs:WP_002306019	DNA topoisomerase III [Enterococcus faecium].	26.50	400	253	7	47	445	241	600	3e-33	142
tr:E4IH74_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.50	400	253	7	47	445	223	582	3e-33	142
tr:K1T893_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC69387.1}; Flags: Fragment;	34.29	315	179	9	86	394	6	298	3e-33	138
gp:CP009031_2334	DNA topoisomerase III, bacteria and conjugative plasmid [Xanthomonas citri subsp. citri]	40.91	176	97	2	36	207	241	413	3e-33	140
rs:WP_033655186	DNA topoisomerase III [Enterococcus faecium].	26.50	400	253	7	47	445	241	600	3e-33	142
rs:WP_033572488	DNA topoisomerase I [Bacteroides sp. UW].	30.08	359	231	9	71	427	273	613	3e-33	142
rs:WP_027384303	DNA topoisomerase I [Chryseobacterium caeni].	29.28	345	233	5	48	391	250	584	3e-33	142
rs:WP_004364188	MULTISPECIES: DNA topoisomerase I [Prevotella].	29.27	386	249	9	43	425	244	608	3e-33	142
rs:WP_041488010	DNA topoisomerase I, partial [Bacillus thuringiensis].	26.16	367	260	6	33	396	237	595	3e-33	142
rs:WP_009413679	DNA topoisomerase [Capnocytophaga sp. oral taxon 326].	30.96	365	229	14	39	391	257	610	3e-33	143
rs:WP_033624436	DNA topoisomerase III [Enterococcus faecium].	26.75	400	252	7	47	445	241	600	3e-33	142
tr:R4BFE2_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.50	400	253	7	47	445	207	566	3e-33	142
rs:WP_019264601	DNA topoisomerase I [Methanobrevibacter smithii].	27.46	426	267	12	38	458	241	629	3e-33	143
rs:WP_033607310	DNA topoisomerase III [Enterococcus faecium].	26.50	400	253	7	47	445	241	600	3e-33	142
tr:C6IR36_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EES67056.2};	31.93	332	216	8	56	385	280	603	3e-33	143
rs:WP_018595759	DNA topoisomerase III [Blautia producta].	30.77	338	217	7	66	397	256	582	3e-33	142
rs:WP_031835761	DNA topoisomerase III, partial [Staphylococcus aureus].	26.18	424	284	11	35	454	213	611	3e-33	142
rs:WP_002672191	DNA topoisomerase [Capnocytophaga ochracea].	30.96	365	229	14	39	391	240	593	3e-33	142
rs:WP_048499056	DNA topoisomerase I [Chryseobacterium koreense].	28.99	345	234	5	48	391	250	584	3e-33	142
rs:WP_017174848	MULTISPECIES: DNA topoisomerase III [Bacteria].	24.40	418	294	7	35	449	227	625	3e-33	142
rs:WP_027952609	DNA topoisomerase I [Hallella seregens].	30.34	356	221	9	74	425	294	626	3e-33	142
rs:WP_031825561	DNA topoisomerase III, partial [Staphylococcus aureus].	26.18	424	284	11	35	454	248	646	3e-33	142
tr:J7HU65_BACTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.16	367	260	6	33	396	237	595	3e-33	142
tr:L2R6Q6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.75	400	252	7	47	445	207	566	3e-33	142
rs:WP_005965580	DNA topoisomerase [Fusobacterium periodonticum].	28.50	407	260	9	37	425	233	626	3e-33	142
rs:WP_021670479	DNA topoisomerase, partial [Prevotella sp. F0091].	29.94	354	225	9	74	425	217	549	3e-33	142
rs:WP_002321930	DNA topoisomerase III [Enterococcus faecium].	26.50	400	253	7	47	445	223	582	3e-33	142
rs:WP_025019241	DNA topoisomerase I [Bacteroides sartorii].	30.03	373	239	9	59	427	259	613	3e-33	142
rs:WP_037541604	DNA topoisomerase III [Staphylococcus sp. M0480].	24.40	418	294	7	35	449	227	625	3e-33	142
rs:WP_042743132	DNA topoisomerase III [Staphylococcus aureus].	26.18	424	284	11	35	454	248	646	3e-33	142
rs:WP_004371701	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	30.59	376	230	10	60	430	263	612	4e-33	142
rs:WP_015807862	DNA topoisomerase III [Pedobacter heparinus].	29.57	328	214	9	59	382	267	581	4e-33	141
rs:WP_044162603	DNA topoisomerase [Salinibacillus aidingensis].	28.26	407	256	10	40	428	252	640	4e-33	142
rs:WP_032575783	DNA topoisomerase I [Bacteroides fragilis].	31.60	326	213	7	60	384	264	580	4e-33	142
rs:WP_010714548	MULTISPECIES: DNA topoisomerase III, partial [Bacilli].	26.18	424	284	11	35	454	248	646	4e-33	142
tr:A0A091CID4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.75	400	252	7	47	445	207	566	4e-33	142
tr:R3I7T2_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.50	400	253	7	47	445	207	566	4e-33	142
tr:S5SY71_LACPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.67	313	202	7	89	397	4	305	4e-33	139
tr:R2NIZ1_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.75	400	252	7	47	445	207	566	4e-33	142
rs:WP_032585698	DNA topoisomerase I [Bacteroides fragilis].	29.95	374	238	12	59	427	259	613	4e-33	142
rs:WP_010764183	DNA topoisomerase III [Enterococcus moraviensis].	27.00	400	251	8	47	445	243	602	4e-33	142
rs:WP_034860927	DNA topoisomerase III [Enterococcus faecalis].	26.82	399	252	6	47	445	205	563	4e-33	142
rs:WP_044755911	DNA topoisomerase [Streptococcus suis].	31.78	365	222	11	37	398	225	565	4e-33	141
tr:A0A073BI74_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.75	400	252	7	47	445	207	566	4e-33	142
rs:WP_001094109	MULTISPECIES: DNA topoisomerase III [Bacilli].	26.18	424	284	11	35	454	248	646	4e-33	142
rs:WP_021396176	DNA topoisomerase [Peptoclostridium difficile].	29.13	357	225	11	47	396	249	584	4e-33	142
rs:WP_016290736	DNA topoisomerase III [Lachnospiraceae bacterium 28-4].	29.26	393	241	13	35	393	259	648	4e-33	142
rs:WP_047209149	DNA topoisomerase III [Staphylococcus aureus].	26.18	424	284	11	35	454	248	646	4e-33	142
rs:WP_026712906	DNA topoisomerase I [Flavobacterium daejeonense].	28.99	345	234	5	48	391	250	584	4e-33	142
rs:WP_002304230	DNA topoisomerase III [Enterococcus faecium].	26.50	400	253	7	47	445	241	600	4e-33	142
rs:WP_031792597	DNA topoisomerase III [Staphylococcus aureus].	26.18	424	284	11	35	454	248	646	4e-33	142
rs:WP_006255807	DNA topoisomerase I [Alloprevotella tannerae].	30.59	376	230	10	60	430	263	612	4e-33	142
rs:WP_002345093	DNA topoisomerase III [Enterococcus faecium].	28.04	403	265	9	44	437	256	642	4e-33	142
rs:WP_004322053	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	30.26	390	242	10	43	427	246	610	4e-33	142
rs:WP_004822267	DNA topoisomerase III [Peptoniphilus indolicus].	27.98	386	236	8	67	449	259	605	4e-33	142
rs:WP_009246241	DNA topoisomerase III [Lachnospiraceae bacterium 6_1_63FAA].	30.12	342	216	11	74	395	301	639	4e-33	142
rs:WP_025477051	DNA topoisomerase [Enterococcus faecium].	28.04	403	265	9	44	437	256	642	4e-33	142
tr:J6YLM5_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.50	400	253	7	47	445	223	582	4e-33	142
rs:WP_009389013	DNA topoisomerase [Capnocytophaga sp. oral taxon 329].	31.06	367	230	14	39	393	240	595	4e-33	142
rs:WP_002339105	DNA topoisomerase III [Enterococcus faecium].	26.75	400	252	7	47	445	241	600	4e-33	142
tr:J6LFB8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.75	400	252	7	47	445	223	582	4e-33	142
tr:C3DWF6_BACTS	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEM37751.1};	27.57	428	266	14	36	450	206	602	4e-33	142
rs:WP_016184912	DNA topoisomerase III [Enterococcus sulfureus].	25.50	400	259	5	41	440	235	595	4e-33	142
rs:WP_004325469	DNA topoisomerase I [Bacteroides ovatus].	29.41	374	243	10	56	427	259	613	4e-33	142
rs:WP_033585993	DNA topoisomerase III [Enterococcus faecium].	26.50	400	253	7	47	445	241	600	5e-33	142
rs:WP_034684347	DNA topoisomerase III [Enterococcus phoeniculicola].	26.30	403	258	7	43	445	237	600	5e-33	142
rs:WP_047929963	DNA topoisomerase [Enterococcus faecium].	28.04	403	265	9	44	437	256	642	5e-33	142
rs:WP_041114280	DNA topoisomerase [Bacillus badius].	30.14	418	243	14	53	450	265	653	5e-33	142
rs:WP_016174178	DNA topoisomerase III [Enterococcus saccharolyticus].	26.43	401	253	7	47	445	241	601	5e-33	142
rs:WP_033641561	DNA topoisomerase III [Enterococcus faecium].	26.75	400	252	7	47	445	241	600	5e-33	142
tr:R3TLQ7_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.30	403	258	7	43	445	218	581	5e-33	142
rs:WP_002594792	DNA topoisomerase III [[Clostridium] clostridioforme].	28.76	386	258	7	47	426	237	611	5e-33	142
rs:WP_044956898	DNA topoisomerase III [Butyrivibrio sp. LC3010].	28.91	422	261	15	40	450	231	624	5e-33	142
rs:WP_033606477	DNA topoisomerase III [Enterococcus faecium].	26.75	400	252	7	47	445	241	600	5e-33	142
rs:WP_032543297	DNA topoisomerase I [Bacteroides fragilis].	29.19	370	242	10	60	427	262	613	5e-33	142
rs:WP_026504229	DNA topoisomerase III [Butyrivibrio sp. NC3005].	30.02	433	245	16	22	400	249	677	5e-33	142
tr:C2HAZ4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.04	403	265	9	44	437	273	659	5e-33	142
rs:WP_025146083	hypothetical protein [Sphingobacterium sp. H1ai].	28.18	369	256	7	65	430	269	631	5e-33	142
rs:WP_035778518	DNA topoisomerase III [Butyrivibrio sp. MC2013].	30.13	395	194	15	71	397	302	682	5e-33	142
rs:WP_004310571	DNA topoisomerase I [Bacteroides ovatus].	31.03	377	226	10	60	430	263	611	5e-33	142
rs:WP_009228524	DNA topoisomerase I [Prevotella sp. oral taxon 299].	27.98	411	266	11	22	425	221	608	5e-33	142
rs:WP_018963384	hypothetical protein [Coprothermobacter platensis].	29.78	413	247	15	56	458	251	630	5e-33	142
rs:WP_042398858	hypothetical protein [Clostridium sp. JCC].	30.51	331	214	8	78	399	262	585	5e-33	142
rs:WP_033629071	DNA topoisomerase III [Enterococcus faecium].	26.75	400	252	7	47	445	241	600	5e-33	142
rs:WP_021908894	DNA topoisomerase III bacteria and conjugative plasmid [Prevotella sp. CAG:755].	30.70	417	259	12	17	427	216	608	5e-33	142
rs:WP_033581948	DNA topoisomerase III [Enterococcus faecium].	26.75	400	252	7	47	445	241	600	5e-33	142
tr:S4DV85_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.75	400	252	7	47	445	223	582	5e-33	142
rs:WP_031876719	DNA topoisomerase III [Staphylococcus aureus].	26.18	424	284	11	35	454	248	646	5e-33	142
tr:R2LGJ5_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.75	400	252	7	47	445	207	566	5e-33	141
rs:WP_003021050	DNA topoisomerase III [Blautia hansenii].	30.12	342	216	11	74	395	301	639	5e-33	142
rs:WP_042987762	DNA topoisomerase I [Bacteroides fragilis].	29.22	373	242	10	59	427	259	613	5e-33	142
rs:WP_008620900	DNA topoisomerase I [Paraprevotella clara].	29.76	373	240	10	59	427	259	613	5e-33	142
rs:WP_031882778	DNA topoisomerase III, partial [Staphylococcus aureus].	26.18	424	284	11	35	454	248	646	5e-33	142
rs:WP_033696774	DNA topoisomerase III [Enterococcus faecium].	26.75	400	252	7	47	445	241	600	6e-33	142
rs:WP_026713482	DNA topoisomerase I [Flavobacterium daejeonense].	28.49	344	234	6	43	384	244	577	6e-33	142
rs:WP_009000847	DNA topoisomerase I [Bacteroides sp. D2].	30.51	354	229	9	60	409	260	600	6e-33	142
tr:J8ZXU3_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.04	403	265	9	44	437	273	659	6e-33	142
tr:S4DYY5_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.82	399	252	6	47	445	223	581	6e-33	141
rs:WP_002335043	DNA topoisomerase III [Enterococcus faecium].	28.04	403	265	9	44	437	256	642	6e-33	142
rs:WP_033606890	DNA topoisomerase III [Enterococcus faecium].	26.75	400	252	7	47	445	241	600	6e-33	142
rs:WP_016276696	DNA topoisomerase III [Bacteroides massiliensis].	28.95	373	243	9	59	427	259	613	6e-33	142
rs:WP_031942101	DNA topoisomerase III, partial [Staphylococcus aureus].	27.76	371	239	11	89	454	9	355	6e-33	139
rs:WP_042145203	DNA topoisomerase [Paucisalibacillus sp. EB02].	28.02	414	254	14	54	450	266	652	6e-33	142
rs:WP_025015836	DNA topoisomerase III [Lactobacillus sakei].	29.12	388	238	6	6	389	199	553	6e-33	142
rs:WP_006785942	DNA topoisomerase [Turicibacter sanguinis].	28.43	401	274	8	34	428	224	617	6e-33	142
rs:WP_005924167	DNA topoisomerase III [Bacteroides salyersiae].	29.81	359	232	9	71	427	273	613	6e-33	142
rs:WP_032845637	DNA topoisomerase I [Bacteroides ovatus].	30.24	377	244	10	54	427	256	616	6e-33	142
tr:A0A0D4ZYL4_STAEP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.64	428	277	12	35	454	248	646	6e-33	142
rs:WP_029200156	DNA topoisomerase III [Oribacterium sp. NK2B42].	28.23	379	230	11	61	401	294	668	6e-33	141
rs:WP_024566104	DNA topoisomerase I, partial [Elizabethkingia anophelis].	27.47	375	257	6	48	421	250	610	6e-33	142
rs:WP_000629137	hypothetical protein, partial [Escherichia coli].	34.23	222	141	2	37	257	65	282	6e-33	136
rs:WP_034211840	DNA topoisomerase [Lachnoanaerobaculum sp. MSX33].	32.72	327	194	9	75	398	262	565	6e-33	140
rs:WP_033795582	DNA topoisomerase III [Enterococcus faecium].	26.75	400	252	7	47	445	241	600	6e-33	141
rs:WP_047937564	DNA topoisomerase [Enterococcus faecium].	28.04	403	265	9	44	437	256	642	6e-33	142
tr:R1YY17_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOF91245.1}; Flags: Fragment;	32.25	276	164	6	186	452	4	265	7e-33	136
tr:R2AXZ8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.50	400	253	7	47	445	207	566	7e-33	141
rs:WP_012896713	DNA topoisomerase III [Staphylococcus aureus].	26.18	424	284	11	35	454	248	646	7e-33	141
rs:WP_033602639	DNA topoisomerase III [Enterococcus faecium].	26.75	400	252	7	47	445	241	600	7e-33	141
rs:WP_032587100	DNA topoisomerase I [Bacteroides fragilis].	29.22	373	242	10	59	427	259	613	7e-33	141
rs:WP_000648780	DNA topoisomerase [Bacillus thuringiensis].	27.57	428	266	14	36	450	249	645	7e-33	142
rs:WP_015548008	DNA topoisomerase III, bacteria and conjugative plasmid [Alistipes shahii].	31.03	377	226	10	60	430	263	611	7e-33	141
tr:E0S4A4_BUTPB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.24	465	281	15	22	445	243	686	7e-33	142
rs:WP_042226552	DNA topoisomerase III [Kingella kingae].	27.59	395	242	10	70	432	258	640	7e-33	141
rs:WP_021849768	DNA topoisomerase III [Firmicutes bacterium CAG:791].	30.71	368	229	13	47	392	278	641	7e-33	141
rs:WP_034552912	DNA topoisomerase III [Carnobacterium funditum].	25.58	430	272	9	26	449	217	604	7e-33	141
rs:WP_025643309	DNA topoisomerase III [[Clostridium] scindens].	30.79	341	214	9	72	392	299	637	8e-33	141
rs:WP_032576687	DNA topoisomerase I [Bacteroides fragilis].	30.24	377	244	10	54	427	256	616	8e-33	141
rs:WP_005348013	DNA topoisomerase [[Eubacterium] hallii].	30.87	392	225	14	54	426	267	631	8e-33	142
rs:WP_005874995	hypothetical protein, partial [Enterococcus faecium].	26.25	400	254	7	47	445	40	399	8e-33	139
rs:WP_032136827	DNA topoisomerase [Kingella sp. Sch538].	27.50	440	265	12	36	443	224	641	8e-33	142
rs:WP_000366635	DNA topoisomerase [Streptococcus agalactiae].	32.23	363	219	10	37	396	225	563	8e-33	140
rs:WP_021419380	DNA topoisomerase [Peptoclostridium difficile].	28.85	357	226	10	47	396	249	584	8e-33	142
rs:WP_011374468	DNA topoisomerase III [Lactobacillus sakei].	28.87	388	239	6	6	389	199	553	8e-33	141
tr:T1DDP8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD79519.1}; Flags: Fragment;	36.24	229	124	4	111	323	1	223	8e-33	135
rs:WP_013671966	DNA topoisomerase I [Prevotella denticola].	33.66	306	183	7	74	375	276	565	8e-33	141
rs:WP_010688141	DNA topoisomerase III [Lactobacillus animalis].	27.65	387	239	6	47	431	241	588	8e-33	141
rs:WP_003002368	DNA topoisomerase [Sphingobacterium spiritivorum].	28.99	345	234	5	48	391	250	584	9e-33	141
tr:W6P9Q2_9BACE	SubName: Full=DNA topoisomerase III, Bacteroidales-type {ECO:0000313|EMBL:CDM06736.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDM06736.1};	30.51	354	223	11	79	427	1	336	9e-33	139
rs:WP_026624798	DNA topoisomerase III [Eggerthia catenaformis].	32.05	365	221	10	37	398	226	566	9e-33	140
rs:WP_014788241	DNA topoisomerase I [Thermococcus cleftensis].	28.26	499	267	17	11	457	214	673	9e-33	141
rs:WP_006798321	DNA topoisomerase I [Dysgonomonas gadei].	30.15	335	219	9	47	377	248	571	9e-33	141
rs:WP_008018278	DNA topoisomerase, partial [Bacteroides xylanisolvens].	34.62	286	176	8	60	344	189	464	9e-33	139
rs:WP_031859997	DNA topoisomerase III [Staphylococcus aureus].	26.18	424	284	11	35	454	248	646	9e-33	141
tr:W4LEV6_9DELT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETW96235.1}; Flags: Fragment;	32.00	300	178	5	160	446	2	288	9e-33	139
rs:WP_048061102	DNA topoisomerase I [Methanothermobacter thermautotrophicus].	27.35	446	273	12	18	453	219	623	9e-33	141
rs:WP_046921879	DNA topoisomerase III [Lactobacillus ruminis].	26.75	385	245	6	47	431	241	588	9e-33	141
rs:WP_035262180	hypothetical protein, partial [Desulfonatronum lacustre].	30.67	375	208	10	54	391	262	621	9e-33	140
rs:WP_011202386	DNA topoisomerase I [Bacteroides fragilis].	29.81	359	232	9	71	427	273	613	9e-33	141
rs:WP_013407034	DNA topoisomerase [Leadbetterella byssophila].	28.99	345	234	5	48	391	250	584	9e-33	141
rs:WP_032135135	DNA topoisomerase I [Alistipes sp. AL-1].	28.29	403	253	11	45	436	246	623	9e-33	141
tr:H1HW63_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.28	422	239	17	3	398	198	594	9e-33	140
rs:WP_031923562	DNA topoisomerase III, partial [Staphylococcus aureus].	27.76	371	239	11	89	454	5	351	1e-32	138
rs:WP_010249847	DNA topoisomerase [Myroides injenensis].	30.70	316	205	7	71	384	273	576	1e-32	141
tr:A0A0C7JSX9_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.01	355	228	8	47	396	247	582	1e-32	141
rs:WP_021375895	DNA topoisomerase [Peptoclostridium difficile].	28.85	357	226	10	47	396	249	584	1e-32	141
rs:WP_012955193	DNA topoisomerase I [Methanobrevibacter ruminantium].	28.73	456	263	14	18	458	219	627	1e-32	141
rs:WP_022010842	DNA topoisomerase III [Firmicutes bacterium CAG:646].	30.17	348	219	9	72	397	304	649	1e-32	141
rs:WP_035447780	DNA topoisomerase III [Lactobacillus animalis].	27.65	387	239	6	47	431	241	588	1e-32	141
gpu:CP009928_787	DNA topoisomerase I [Chryseobacterium gallinarum]	31.66	319	207	5	74	391	277	585	1e-32	141
rs:WP_028069430	DNA topoisomerase I [Sphingobacterium thalpophilum].	31.23	349	221	8	48	391	250	584	1e-32	141
rs:WP_013632654	DNA topoisomerase [Pseudopedobacter saltans].	28.99	345	234	5	48	391	250	584	1e-32	141
rs:WP_014298481	DNA topoisomerase I [Bacteroides fragilis].	29.81	359	232	9	71	427	273	613	1e-32	141
tr:A0A0B8P485_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAM61590.1};	36.65	191	113	1	200	390	2	184	1e-32	134
rs:WP_033612353	DNA topoisomerase III [Enterococcus faecium].	26.50	400	253	7	47	445	241	600	1e-32	141
rs:WP_016662202	DNA topoisomerase III [Bacteroides stercoris].	29.81	359	232	9	71	427	273	613	1e-32	141
rs:WP_004907636	hypothetical protein [Acinetobacter junii].	30.13	395	236	15	28	398	242	620	1e-32	142
rs:WP_004326100	MULTISPECIES: DNA topoisomerase I [Bacteroides].	29.81	359	232	9	71	427	273	613	1e-32	141
rs:WP_002329190	DNA topoisomerase [Enterococcus faecium].	28.04	403	265	9	44	437	256	642	1e-32	141
rs:WP_031538172	MULTISPECIES: DNA topoisomerase [Bacillus].	30.29	416	247	17	50	450	262	649	1e-32	141
rs:WP_029881403	MULTISPECIES: hypothetical protein [Paenibacillus].	27.34	395	267	7	41	421	227	615	1e-32	141
rs:WP_007173335	DNA topoisomerase I [Prevotella bergensis].	27.32	410	272	10	22	426	221	609	1e-32	141
rs:WP_047480025	DNA topoisomerase I [Chryseobacterium sp. CF356].	28.70	345	235	5	48	391	250	584	1e-32	141
rs:WP_002979405	DNA topoisomerase [Chryseobacterium gleum].	28.12	345	237	5	48	391	250	584	1e-32	141
rs:WP_013466927	DNA topoisomerase I [Thermococcus barophilus].	28.23	464	252	14	40	457	246	674	1e-32	141
rs:WP_037598662	DNA topoisomerase [Streptococcus sp. AS20].	32.51	366	220	10	35	397	223	564	1e-32	139
rs:WP_033627502	DNA topoisomerase, partial [Enterococcus faecium].	33.81	278	165	7	93	365	17	280	1e-32	139
rs:WP_013710309	DNA topoisomerase III [Carnobacterium sp. 17-4].	27.04	355	222	5	40	390	234	555	1e-32	140
rs:WP_009432418	DNA topoisomerase, partial [Porphyromonas sp. oral taxon 279].	27.91	412	265	13	22	425	123	510	1e-32	140
rs:WP_048087612	DNA topoisomerase [Metallosphaera yellowstonensis].	28.49	344	204	7	59	398	241	546	1e-32	140
rs:WP_002566666	DNA topoisomerase III [[Clostridium] bolteae].	29.97	327	212	7	65	385	255	570	1e-32	140
tr:A0A0A0WVM8_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.99	368	244	10	93	454	4	356	1e-32	139
rs:WP_026984412	DNA topoisomerase I [Flavobacterium sp. URHB0058].	27.79	367	250	6	56	421	259	611	1e-32	140
rs:WP_022011364	DNA topoisomerase III [Bacteroides fragilis CAG:558].	30.23	344	222	8	43	384	72	399	1e-32	139
rs:WP_005794081	DNA topoisomerase I [Bacteroides fragilis].	30.27	370	233	10	60	427	263	609	1e-32	140
sp:TOP1_METTH	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	27.35	446	273	12	18	453	226	630	1e-32	141
rs:WP_022345820	DNA topoisomerase [Clostridium sp. CAG:299].	28.46	390	232	11	47	392	271	657	1e-32	140
rs:WP_033698011	DNA topoisomerase III [Enterococcus faecium].	26.25	400	254	7	47	445	241	600	1e-32	140
rs:WP_047936940	DNA topoisomerase [Enterococcus faecium].	28.04	403	265	9	44	437	256	642	1e-32	141
rs:WP_002978178	DNA topoisomerase [Chryseobacterium gleum].	28.87	336	223	7	59	391	261	583	1e-32	140
rs:WP_029503437	DNA topoisomerase III [Lachnoclostridium phytofermentans].	29.87	375	216	13	61	392	316	686	1e-32	141
rs:WP_035439122	DNA topoisomerase III, partial [Bacillus sp. RP1137].	33.22	304	170	10	167	453	2	289	1e-32	137
rs:WP_025698624	DNA topoisomerase III, partial [Paenibacillus durus].	36.24	218	135	3	38	253	233	448	1e-32	138
rs:WP_041779466	DNA topoisomerase I, partial [Belliella baltica].	30.03	333	220	6	43	372	244	566	1e-32	139
rs:WP_046922005	DNA topoisomerase III [Lactobacillus ruminis].	26.75	385	245	6	47	431	241	588	1e-32	140
tr:U3N9M1_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.63	333	216	5	50	378	1	322	1e-32	138
rs:WP_004319756	DNA topoisomerase I [Bacteroides ovatus].	30.51	354	229	9	60	409	260	600	1e-32	140
rs:WP_044135992	DNA topoisomerase I [Bacteroides fragilis].	30.51	354	229	9	60	409	260	600	1e-32	140
rs:WP_025279158	DNA topoisomerase I [Barnesiella viscericola].	28.72	383	252	10	49	427	251	616	1e-32	140
rs:WP_008754320	DNA topoisomerase [Lachnoanaerobaculum saburreum].	33.03	330	195	9	66	392	253	559	1e-32	139
rs:WP_036178576	hypothetical protein, partial [Lysinibacillus massiliensis].	30.72	306	187	5	121	425	25	306	1e-32	137
rs:WP_008775022	DNA topoisomerase I [Bacteroides sp. 2_2_4].	30.23	354	230	9	60	409	260	600	1e-32	140
rs:WP_023168138	DNA topoisomerase III, partial [Salmonella enterica].	37.11	194	116	1	192	385	2	189	2e-32	134
tr:S4E644_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.04	403	265	9	44	437	273	659	2e-32	141
rs:WP_031388728	DNA topoisomerase III, partial [Desulfonatronum thiodismutans].	29.47	380	205	10	54	391	262	620	2e-32	140
tr:I3Z129_BELBD	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.94	334	221	6	43	373	244	567	2e-32	139
rs:WP_019035128	DNA topoisomerase III [Peptoniphilus lacrimalis].	32.08	371	220	12	31	396	220	563	2e-32	139
rs:WP_035637696	DNA topoisomerase III [Lachnospiraceae bacterium ND2006].	29.84	449	264	18	27	450	214	636	2e-32	140
rs:WP_002330030	DNA topoisomerase III, partial [Enterococcus faecium].	26.25	400	254	7	47	445	207	566	2e-32	140
rs:WP_002349400	DNA topoisomerase, partial [Enterococcus faecium].	33.70	276	168	6	93	365	8	271	2e-32	135
rs:WP_018362612	DNA topoisomerase I [Prevotella nanceiensis].	27.74	411	267	11	22	425	221	608	2e-32	140
rs:WP_009071258	DNA topoisomerase [Metallosphaera yellowstonensis].	28.49	344	204	7	59	398	253	558	2e-32	140
tr:J6WLB4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.25	400	254	6	47	445	223	582	2e-32	140
tr:S4EWF5_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.25	400	254	7	47	445	223	582	2e-32	140
rs:WP_022398796	DNA topoisomerase [Roseburia sp. CAG:471].	31.16	353	207	12	72	396	319	663	2e-32	140
rs:WP_035458073	DNA topoisomerase I [Bacteroides uniformis].	29.27	369	238	11	65	427	265	616	2e-32	140
rs:WP_025001427	DNA topoisomerase I [Prevotella aurantiaca].	27.49	411	268	11	22	425	221	608	2e-32	140
rs:WP_039122908	DNA topoisomerase III [Lactobacillus ruminis].	26.49	385	246	6	47	431	241	588	2e-32	140
rs:WP_039372716	DNA topoisomerase I [Chryseobacterium taiwanense].	28.38	370	245	9	22	384	221	577	2e-32	140
rs:WP_033643829	MULTISPECIES: DNA topoisomerase III [Enterococcus].	26.25	400	254	7	47	445	241	600	2e-32	140
rs:WP_033651462	DNA topoisomerase III [Enterococcus faecium].	26.25	400	254	6	47	445	241	600	2e-32	140
rs:WP_006842135	DNA topoisomerase I [Dysgonomonas mossii].	30.60	317	210	8	74	385	277	588	2e-32	140
rs:WP_042631280	DNA topoisomerase III [Bacillus cereus].	28.22	411	266	11	57	448	278	678	2e-32	140
rs:WP_021938600	DNA topoisomerase [Coprococcus sp. CAG:782].	29.04	365	234	12	56	401	111	469	2e-32	138
rs:WP_033693711	DNA topoisomerase III [Bacillus cereus].	28.22	411	266	11	57	448	278	678	2e-32	140
rs:WP_007790408	DNA topoisomerase III [Peptostreptococcus stomatis].	32.44	336	201	9	66	398	253	565	2e-32	139
rs:WP_033584975	DNA topoisomerase III [Enterococcus faecium].	26.25	400	254	7	47	445	241	600	2e-32	140
rs:WP_023177191	DNA topoisomerase III [Carnobacterium sp. WN1359].	26.60	391	239	8	47	431	241	589	2e-32	140
tr:H1DE94_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EHP49991.1};	29.26	393	250	11	43	427	246	618	2e-32	140
tr:C2TQW3_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.22	411	266	11	57	448	274	674	2e-32	140
rs:WP_033655380	DNA topoisomerase III [Enterococcus faecium].	26.25	400	254	7	47	445	241	600	2e-32	140
rs:WP_000280356	hypothetical protein [Bacillus cereus].	28.22	411	266	11	57	448	278	678	2e-32	140
tr:A0A0E6CWC9_SALTI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CQY73910.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CQY73910.1};	36.55	197	119	1	189	385	1	191	2e-32	134
rs:WP_040611578	DNA topoisomerase I [Odoribacter laneus].	29.26	393	250	11	43	427	244	616	2e-32	140
rs:WP_002344214	DNA topoisomerase III [Enterococcus faecium].	27.79	403	266	9	44	437	256	642	2e-32	140
rs:WP_016284650	DNA topoisomerase III [Lachnospiraceae bacterium A4].	30.90	411	246	13	23	426	227	606	2e-32	140
rs:WP_032535951	DNA topoisomerase I [Bacteroides fragilis].	29.81	359	232	9	71	427	273	613	2e-32	140
rs:WP_024399802	DNA topoisomerase [Streptococcus suis].	30.96	365	225	10	37	398	226	566	2e-32	139
rs:WP_040800395	DNA topoisomerase III [Stomatobaculum longum].	31.28	422	239	17	3	398	245	641	2e-32	140
rs:WP_016682821	DNA topoisomerase III, partial [Yersinia pestis].	38.76	209	122	3	27	233	183	387	2e-32	137
rs:WP_016169468	DNA topoisomerase III [Lachnospiraceae bacterium 10-1].	29.40	364	227	13	65	402	294	653	2e-32	140
rs:WP_040110015	hypothetical protein, partial [Thalassospira xiamenensis].	28.91	377	226	9	36	374	229	601	2e-32	139
rs:WP_046420055	hypothetical protein [Xylella fastidiosa].	65.56	90	31	0	29	118	35	124	2e-32	130
gpu:CP007655_60	hypothetical protein [Vibrio cholerae]	28.73	442	255	14	19	414	274	701	2e-32	141
rs:WP_035518992	DNA topoisomerase, partial [Burkholderia sp. Ch1-1].	33.33	273	170	3	40	310	260	522	2e-32	138
rs:WP_022280887	DNA topoisomerase [Lactobacillus ruminis CAG:367].	26.34	391	251	6	41	431	235	588	2e-32	140
rs:WP_047383946	DNA topoisomerase I [Chryseobacterium sp. YR485].	28.84	371	234	9	20	386	240	584	2e-32	140
tr:A0A0C7IT59_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.01	355	228	8	47	396	247	582	2e-32	140
tr:R9HYZ0_BACUN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOS06385.1};	29.27	369	238	11	65	427	294	645	2e-32	140
rs:WP_040220752	DNA topoisomerase III, partial [Klebsiella pneumoniae].	33.62	229	147	2	37	264	221	445	3e-32	137
tr:A0A0C7I5E1_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.73	355	229	8	47	396	247	582	3e-32	140
tr:A0A0C7RDW4_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.01	355	228	8	47	396	247	582	3e-32	140
rs:WP_033797970	hypothetical protein [Bacillus mycoides].	27.63	409	255	12	58	454	268	647	3e-32	140
rs:WP_033017430	DNA topoisomerase III [Geobacillus stearothermophilus].	27.39	398	249	14	74	454	210	584	3e-32	139
rs:WP_025068869	DNA topoisomerase I [Bacteroides gallinarum].	28.38	370	248	9	60	427	262	616	3e-32	140
rs:WP_023052298	hypothetical protein [Cetobacterium somerae].	28.00	375	245	8	37	399	306	667	3e-32	140
rs:WP_026526973	DNA topoisomerase III [Butyrivibrio sp. VCD2006].	29.50	417	252	14	22	400	245	657	3e-32	140
tr:A0A0C7Q4Q1_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.01	355	228	8	47	396	247	582	3e-32	140
rs:WP_026649430	DNA topoisomerase III [Blautia wexlerae].	28.09	413	240	13	35	393	259	668	3e-32	140
tr:A0A0C7LPY8_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.73	355	229	8	47	396	247	582	3e-32	140
rs:WP_038700296	DNA topoisomerase I [Sphingobacterium sp. ML3W].	28.49	337	230	5	56	391	259	585	3e-32	140
tr:A0A0C7G0C3_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.01	355	228	8	47	396	247	582	3e-32	140
rs:WP_034538462	DNA topoisomerase III [Carnobacterium inhibens].	26.60	391	239	8	47	431	241	589	3e-32	140
rs:WP_044545505	DNA topoisomerase I [Parabacteroides distasonis].	30.51	354	229	9	60	409	260	600	3e-32	140
rs:WP_024981683	DNA topoisomerase I [Flavobacterium succinicans].	29.63	324	207	7	74	391	277	585	3e-32	140
rs:WP_010803479	MULTISPECIES: DNA topoisomerase III [Parabacteroides].	28.92	370	243	9	60	427	262	613	3e-32	140
rs:WP_035066874	hypothetical protein, partial [Carnobacterium maltaromaticum].	27.47	375	242	7	61	434	271	616	3e-32	139
rs:WP_006268790	DNA topoisomerase III [Streptococcus constellatus].	31.61	367	216	10	37	396	225	563	3e-32	138
tr:T0N6P8_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.85	395	239	15	95	458	12	391	3e-32	137
rs:WP_025070215	DNA topoisomerase I [Prevotella oulorum].	30.06	356	222	9	74	425	276	608	3e-32	139
rs:WP_000366634	DNA topoisomerase [Streptococcus agalactiae].	31.96	363	220	10	37	396	225	563	3e-32	138
rs:WP_008628880	DNA topoisomerase, partial [Paraprevotella xylaniphila].	33.77	302	178	9	60	360	51	331	3e-32	135
rs:WP_013773769	DNA topoisomerase III [Melissococcus plutonius].	26.93	401	250	8	47	445	243	602	3e-32	139
rs:WP_026520344	DNA topoisomerase III [Butyrivibrio sp. FCS006].	29.89	435	231	15	22	400	246	662	3e-32	139
rs:WP_018109310	DNA topoisomerase I [Bacteroides propionicifaciens].	30.53	357	221	9	74	426	276	609	3e-32	139
rs:WP_018968363	DNA topoisomerase I [Prevotella loescheii].	30.62	356	220	9	74	425	276	608	3e-32	139
tr:L2MPF4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.25	400	254	7	47	445	207	566	3e-32	139
rs:WP_016095076	DNA topoisomerase 1 [Bacillus cereus].	26.12	425	295	10	35	454	239	649	4e-32	140
rs:WP_032599027	DNA topoisomerase I [Bacteroides fragilis].	31.12	347	225	9	56	400	258	592	4e-32	139
rs:WP_007654023	DNA topoisomerase I [Parabacteroides goldsteinii].	30.50	377	229	12	60	430	263	612	4e-32	139
rs:WP_018593291	DNA topoisomerase III [Blautia producta].	29.03	403	216	11	56	445	244	589	4e-32	139
rs:WP_002978408	MULTISPECIES: DNA topoisomerase [Chryseobacterium].	28.70	345	235	5	48	391	250	584	4e-32	139
rs:WP_026905925	DNA topoisomerase [Paucisalibacillus globulus].	28.93	394	236	14	74	450	286	652	4e-32	139
rs:WP_033606645	DNA topoisomerase III [Enterococcus faecium].	26.25	400	254	7	47	445	241	600	4e-32	139
rs:WP_020365500	DNA topoisomerase III, partial [Staphylococcus epidermidis].	28.18	401	258	12	59	445	271	655	4e-32	139
rs:WP_042258672	DNA topoisomerase III, partial [Butyrivibrio proteoclasticus].	27.39	376	236	11	41	392	263	625	4e-32	139
tr:F3J5T6_PSEAP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGH79762.1}; Flags: Fragment;	35.58	208	132	1	201	408	1	206	4e-32	133
rs:WP_042994218	DNA topoisomerase I [Bacteroides fragilis].	30.23	354	230	9	60	409	260	600	4e-32	139
rs:WP_031504379	DNA topoisomerase I [Chryseobacterium haifense].	28.70	345	235	5	48	391	250	584	4e-32	139
rs:WP_018591436	DNA topoisomerase [Terrisporobacter glycolicus].	28.85	357	226	9	47	396	249	584	4e-32	139
rs:WP_007483903	DNA topoisomerase I [Bacteroides nordii].	30.70	355	227	10	60	409	260	600	4e-32	139
rs:WP_002135700	DNA topoisomerase [Bacillus cereus].	27.17	427	269	14	36	450	249	645	4e-32	139
tr:A0A0C7JCB9_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.85	357	226	9	47	396	247	582	4e-32	139
rs:WP_010732632	DNA topoisomerase III [Enterococcus faecium].	28.04	403	265	9	44	437	256	642	4e-32	139
rs:WP_016268745	DNA topoisomerase III [Bacteroides thetaiotaomicron].	30.51	354	229	9	60	409	260	600	5e-32	139
rs:WP_040191961	DNA topoisomerase [Clostridium sp. CL-6].	28.28	435	254	14	50	452	271	679	5e-32	139
rs:WP_035431967	DNA topoisomerase [Atopobium parvulum].	28.28	435	254	14	40	459	291	682	5e-32	140
rs:WP_011888497	DNA topoisomerase III [Geobacillus thermodenitrificans].	27.20	397	251	13	74	454	282	656	5e-32	139
rs:WP_021966453	DNA topoisomerase III [Clostridium sp. CAG:149].	28.34	434	263	14	3	392	228	657	5e-32	139
rs:WP_009433650	DNA topoisomerase I [Porphyromonas sp. oral taxon 279].	27.67	412	266	13	22	425	221	608	5e-32	139
tr:A0A0C7HPT5_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.73	355	229	8	47	396	247	582	5e-32	139
tr:A0A0C7TBY2_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.73	355	229	8	47	396	247	582	5e-32	139
rs:WP_047922364	DNA topoisomerase [Neisseria gonorrhoeae].	26.47	442	271	9	36	443	224	645	5e-32	139
tr:A0A0B4Y581_9PROT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AJD54325.1};	28.91	377	226	9	36	374	229	601	5e-32	140
rs:WP_018910191	DNA topoisomerase I [Prevotella veroralis].	30.34	356	221	9	74	425	276	608	5e-32	139
rs:WP_026522671	DNA topoisomerase III [Butyrivibrio sp. VCB2001].	29.89	435	231	15	22	400	246	662	5e-32	139
rs:WP_021385283	DNA topoisomerase [Peptoclostridium difficile].	29.64	361	218	12	47	396	249	584	5e-32	139
rs:WP_035435739	DNA topoisomerase [Atopobium sp. BS2].	28.05	435	255	14	40	459	291	682	5e-32	140
rs:WP_032843242	DNA topoisomerase I [Bacteroides ovatus].	30.62	356	226	9	60	409	260	600	5e-32	139
rs:WP_025232898	DNA topoisomerase III [Clostridium sp. ASBs410].	28.46	390	226	13	59	397	295	682	5e-32	139
rs:WP_035021888	DNA topoisomerase III [Carnobacterium sp. WN1374].	26.76	355	223	5	40	390	234	555	5e-32	139
rs:WP_004353783	DNA topoisomerase I [Prevotella denticola].	31.11	315	197	7	74	384	276	574	5e-32	139
tr:A0A0A8VTK4_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.77	351	226	8	47	392	247	578	6e-32	139
tr:A0A0C7HUT9_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.73	355	229	8	47	396	247	582	6e-32	139
rs:WP_024635188	DNA topoisomerase [Enterococcus faecium].	28.21	390	255	9	57	437	269	642	6e-32	139
rs:WP_020367186	DNA topoisomerase III [Staphylococcus epidermidis].	28.18	401	258	12	59	445	271	655	6e-32	139
rs:WP_022769064	DNA topoisomerase III [Butyrivibrio sp. NC2007].	30.57	435	228	16	22	400	246	662	6e-32	139
tr:E1GTM7_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFN91994.1};	28.37	356	228	9	74	425	45	377	6e-32	137
rs:WP_007566594	DNA topoisomerase I [Bacteroides coprocola].	30.84	347	210	11	60	393	264	593	6e-32	139
rs:WP_016264956	DNA topoisomerase III [Lactobacillus sakei].	28.76	386	238	6	6	387	199	551	6e-32	139
rs:WP_008141550	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	29.38	371	235	10	60	427	263	609	6e-32	139
rs:WP_002844059	DNA topoisomerase [Peptostreptococcus anaerobius].	27.82	363	235	8	47	402	249	591	6e-32	139
rs:WP_025068261	DNA topoisomerase I [Prevotella denticola].	30.28	327	212	6	60	384	262	574	6e-32	139
rs:WP_024060732	DNA topoisomerase, partial [Veillonella dispar].	37.67	215	115	4	209	404	2	216	6e-32	132
tr:J7CXS9_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.11	402	256	11	44	427	273	659	6e-32	139
rs:WP_042942923	DNA topoisomerase III, partial [Klebsiella pneumoniae].	42.14	159	88	3	36	193	57	212	6e-32	131
rs:WP_000280353	DNA topoisomerase III [Bacillus cereus].	27.98	411	267	11	57	448	278	678	6e-32	139
rs:WP_003321296	DNA topoisomerase [Bacillus alcalophilus].	29.44	394	241	14	69	450	281	649	6e-32	139
tr:L8A5I9_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.00	400	255	7	47	445	207	566	6e-32	138
tr:S3JEW5_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	42.14	159	88	3	36	193	57	212	6e-32	131
tr:A0A0C7GCE7_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.73	355	229	8	47	396	247	582	6e-32	139
tr:A0A0C7T5M5_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.73	355	229	8	47	396	247	582	6e-32	139
rs:WP_046177003	DNA topoisomerase [Streptococcus dysgalactiae].	32.33	365	218	11	37	397	225	564	6e-32	137
rs:WP_042410060	DNA topoisomerase III [Geobacillus caldoxylosilyticus].	27.20	397	251	13	74	454	282	656	6e-32	139
rs:WP_010891344	hypothetical protein, partial [Streptococcus agalactiae].	32.04	284	168	7	182	455	1	269	6e-32	134
rs:WP_029276362	MULTISPECIES: DNA topoisomerase III [Carnobacterium].	25.96	389	244	7	47	431	241	589	6e-32	139
rs:WP_032882988	DNA topoisomerase, partial [Fusobacterium nucleatum].	26.42	424	282	8	40	448	139	547	6e-32	137
rs:WP_044146630	DNA topoisomerase [Enterococcus faecium].	28.11	402	256	11	44	427	256	642	7e-32	139
tr:L2IN04_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELA69015.1};	34.06	276	170	5	57	329	110	376	7e-32	135
rs:WP_044168813	DNA topoisomerase I [Porphyromonas catoniae].	28.16	412	264	13	22	425	221	608	7e-32	139
rs:WP_025478277	DNA topoisomerase [Enterococcus faecium].	28.11	402	256	11	44	427	256	642	7e-32	139
rs:WP_012301124	TrsI protein [Geobacillus stearothermophilus].	27.20	397	251	13	74	454	282	656	7e-32	139
rs:WP_019595521	DNA topoisomerase [Peptostreptococcus anaerobius].	27.82	363	235	8	47	402	249	591	7e-32	139
rs:WP_032588335	MULTISPECIES: DNA topoisomerase I [Bacteroides].	29.81	359	232	9	71	427	273	613	7e-32	139
rs:WP_042512886	DNA topoisomerase [Bacillus cereus].	27.00	426	271	13	36	450	249	645	7e-32	139
rs:WP_007215190	DNA topoisomerase I [Bacteroides cellulosilyticus].	32.62	325	197	9	57	377	259	565	7e-32	139
rs:WP_035305590	DNA topoisomerase, partial [Clostridium sp. HMP27].	28.85	409	240	13	67	452	10	390	7e-32	136
rs:WP_008881726	DNA topoisomerase III [Geobacillus sp. G11MC16].	27.20	397	251	13	74	454	282	656	7e-32	139
tr:J4W6P3_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.31	325	194	9	75	396	217	518	7e-32	137
tr:A0A0C7S4V2_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.73	355	229	8	47	396	247	582	7e-32	139
rs:WP_024636303	DNA topoisomerase [Enterococcus faecium].	28.21	390	255	9	57	437	269	642	7e-32	139
rs:WP_032583404	DNA topoisomerase I, partial [Bacteroides fragilis].	31.66	338	212	10	93	427	2	323	7e-32	135
rs:WP_032568995	DNA topoisomerase I [Bacteroides fragilis].	31.53	333	210	6	60	391	295	610	7e-32	139
rs:WP_031862612	DNA topoisomerase III, partial [Staphylococcus aureus].	26.26	396	269	8	35	427	248	623	7e-32	138
tr:W4V045_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE86442.1};	31.66	338	214	11	45	377	158	483	8e-32	137
rs:WP_038398917	DNA topoisomerase [Enterococcus faecium].	28.11	402	256	11	44	427	256	642	8e-32	139
tr:R2SAC7_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.91	321	208	6	77	392	2	310	8e-32	136
rs:WP_002484399	MULTISPECIES: DNA topoisomerase III [Staphylococcus].	28.25	400	259	11	59	445	271	655	8e-32	139
rs:WP_002845103	DNA topoisomerase [Peptostreptococcus anaerobius].	27.82	363	235	8	47	402	249	591	8e-32	139
rs:WP_003693017	DNA topoisomerase III [Lactobacillus ruminis].	26.09	391	252	6	41	431	235	588	8e-32	138
tr:A0A0F5ISM2_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KKB48508.1};	29.81	359	232	9	71	427	263	603	8e-32	138
rs:WP_033795073	DNA topoisomerase III [Enterococcus faecium].	26.00	400	255	7	47	445	241	600	8e-32	138
rs:WP_046923262	DNA topoisomerase III [Lactobacillus ruminis].	26.34	391	251	6	41	431	235	588	8e-32	138
rs:WP_034978567	DNA topoisomerase I [Epilithonimonas lactis].	27.99	368	238	8	70	421	274	630	8e-32	138
rs:WP_004051183	DNA topoisomerase III [Lactobacillus murinus].	27.66	394	242	6	41	431	235	588	8e-32	138
rs:WP_044115448	DNA topoisomerase I [Porphyromonas sp. KLE 1280].	27.67	412	266	13	22	425	221	608	8e-32	138
rs:WP_044345975	DNA topoisomerase III, partial [Pseudomonas meliae].	37.88	198	120	2	36	233	123	317	8e-32	134
tr:H1HC00_FUSNU	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EHO79969.1}; Flags: Fragment;	27.11	402	269	7	40	426	171	563	8e-32	138
rs:WP_006892423	DNA topoisomerase [Methylobacter tundripaludum].	28.31	378	242	9	37	395	231	598	8e-32	139
rs:WP_021128957	DNA topoisomerase [[Clostridium] sordellii].	26.68	431	260	11	47	450	247	648	9e-32	139
rs:WP_046159436	MULTISPECIES: DNA topoisomerase [Streptococcus].	32.78	363	217	10	37	396	225	563	9e-32	137
rs:WP_042735322	DNA topoisomerase III [Lachnospiraceae bacterium TWA4].	30.84	334	215	11	72	393	298	627	9e-32	138
tr:A0A0D0S6Q2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.84	334	215	11	72	393	275	604	9e-32	137
rs:WP_025883360	DNA topoisomerase I [Porphyromonas uenonis].	32.69	309	187	8	74	378	276	567	9e-32	138
tr:A0A0C7RPC2_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.73	355	229	8	47	396	247	582	9e-32	138
tr:A0A0A1S3R0_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.45	355	230	8	47	396	247	582	9e-32	138
rs:WP_020331515	DNA topoisomerase III [Vibrio fluvialis].	28.73	442	255	14	19	414	274	701	9e-32	139
rs:WP_045592690	hypothetical protein [Vibrio vulnificus].	28.73	442	255	14	19	414	274	701	9e-32	139
tr:S4EDR9_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.18	401	271	7	44	437	86	472	9e-32	137
rs:WP_026161838	DNA topoisomerase I [Porphyromonas somerae].	31.82	308	191	7	74	378	276	567	9e-32	138
tr:A8U7S1_9LACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.96	389	244	7	47	431	251	599	9e-32	138
tr:A0A0C7QL11_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.73	355	229	8	47	396	247	582	9e-32	138
rs:WP_007482644	MULTISPECIES: DNA topoisomerase I [Bacteroides].	29.81	359	232	9	71	427	273	613	9e-32	138
tr:A0A0C7R9A4_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.17	355	231	8	47	396	247	582	1e-31	138
rs:WP_042957237	DNA topoisomerase, partial [Enterococcus faecium].	33.70	276	168	6	93	365	12	275	1e-31	135
rs:WP_016195967	DNA topoisomerase III [Arcticibacter svalbardensis].	28.50	400	256	14	59	450	267	644	1e-31	138
rs:WP_003068295	DNA topoisomerase [Streptococcus intermedius].	32.42	364	219	10	37	397	225	564	1e-31	137
rs:WP_034669318	MULTISPECIES: DNA topoisomerase I [Chryseobacterium].	29.60	348	216	8	49	391	261	584	1e-31	138
rs:WP_034217778	DNA topoisomerase III, partial [Lachnospiraceae bacterium AB2028].	29.95	364	218	8	48	396	244	585	1e-31	137
rs:WP_039419382	DNA topoisomerase I [Porphyromonas gulae].	30.56	337	217	9	59	391	259	582	1e-31	138
rs:WP_007653480	DNA topoisomerase I [Parabacteroides goldsteinii].	29.94	354	231	9	60	409	260	600	1e-31	138
rs:WP_016479364	DNA topoisomerase III [Capnocytophaga sp. oral taxon 336].	30.22	364	233	13	39	391	240	593	1e-31	138
rs:WP_011954063	DNA topoisomerase I [Methanobrevibacter smithii].	27.00	426	269	12	38	458	241	629	1e-31	138
rs:WP_007216070	DNA topoisomerase I [Bacteroides cellulosilyticus].	29.94	354	231	9	60	409	260	600	1e-31	138
rs:WP_002352070	DNA topoisomerase, partial [Enterococcus faecium].	33.70	276	168	6	93	365	5	268	1e-31	134
tr:D4VUU6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.89	360	231	8	44	392	256	601	1e-31	137
rs:WP_010777139	DNA topoisomerase III [Enterococcus faecium].	27.86	402	257	11	44	427	256	642	1e-31	138
rs:WP_004602163	DNA topoisomerase III [[Eubacterium] cellulosolvens].	31.87	364	202	12	72	392	300	660	1e-31	138
rs:WP_022386816	hypothetical protein [Collinsella sp. CAG:289].	27.51	429	255	11	40	454	288	674	1e-31	139
rs:WP_016532565	DNA topoisomerase III, partial [Klebsiella pneumoniae].	36.65	191	115	1	195	385	2	186	1e-31	131
rs:WP_036857289	DNA topoisomerase I [Prevotella denticola].	28.93	356	226	9	74	425	276	608	1e-31	138
tr:J2T8C6_9FLAO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJL74342.1};	29.60	348	216	8	49	391	285	608	1e-31	138
rs:WP_047437492	DNA topoisomerase I [Chryseobacterium sp. YR561].	27.30	403	265	8	20	421	240	615	1e-31	138
rs:WP_002324101	DNA topoisomerase III [Enterococcus faecium].	27.86	402	257	11	44	427	256	642	1e-31	138
rs:WP_017473361	hypothetical protein [Amphibacillus jilinensis].	27.54	443	276	13	25	446	232	650	1e-31	138
rs:WP_043043642	hypothetical protein, partial [Streptococcus equi].	29.33	416	258	12	26	428	233	625	1e-31	137
rs:WP_002319742	DNA topoisomerase [Enterococcus faecium].	28.11	402	256	11	44	427	256	642	1e-31	138
rs:WP_001094110	MULTISPECIES: DNA topoisomerase III [Staphylococcus].	26.40	428	278	12	35	454	248	646	1e-31	138
rs:WP_004032475	DNA topoisomerase I [Methanobrevibacter smithii].	27.00	426	269	12	38	458	241	629	1e-31	138
rs:WP_021907748	DNA topoisomerase [Eubacterium sp. CAG:146].	29.67	391	231	13	54	426	267	631	1e-31	138
rs:WP_017144927	DNA topoisomerase [Fusobacterium nucleatum].	27.11	402	269	7	40	426	236	628	1e-31	138
rs:WP_036865053	DNA topoisomerase I [Porphyromonas sp. COT-108 OH2963].	30.57	314	201	6	74	384	276	575	1e-31	137
tr:A0A0E2SWY0_BACFG	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EXZ78927.1};	30.16	368	238	7	61	427	216	565	1e-31	137
tr:A0A0C7NNS0_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.73	355	229	8	47	396	247	582	2e-31	138
rs:WP_011860791	DNA topoisomerase [Peptoclostridium difficile].	32.33	365	216	11	37	396	225	563	2e-31	136
rs:WP_045221390	hypothetical protein, partial [Desulfonatronum thioautotrophicum].	29.01	362	202	9	52	374	260	605	2e-31	137
tr:C9ANH7_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.95	390	256	9	57	437	199	572	2e-31	137
rs:WP_008015944	DNA topoisomerase, partial [Bacteroides xylanisolvens].	34.27	286	169	7	60	344	263	530	2e-31	136
rs:WP_012263515	TrsI [Staphylococcus aureus].	25.94	424	285	11	35	454	248	646	2e-31	137
rs:WP_029199505	DNA topoisomerase III [Oribacterium sp. NK2B42].	29.81	369	241	8	61	425	251	605	2e-31	137
rs:WP_035063737	DNA topoisomerase III [Carnobacterium maltaromaticum].	26.63	353	224	4	40	390	234	553	2e-31	137
rs:WP_016624844	DNA topoisomerase [Enterococcus faecalis].	31.92	354	207	12	93	427	305	643	2e-31	138
rs:WP_000779854	DNA topoisomerase [Streptococcus agalactiae].	31.40	363	222	10	37	396	225	563	2e-31	136
rs:WP_039420015	DNA topoisomerase I [Porphyromonas gulae].	30.30	330	213	9	59	384	259	575	2e-31	137
rs:WP_034692209	DNA topoisomerase I [Chryseobacterium sp. CF365].	29.08	368	237	7	20	386	240	584	2e-31	137
rs:WP_026769694	DNA topoisomerase I [Sediminibacterium sp. OR53].	29.89	348	227	7	48	391	249	583	2e-31	137
rs:WP_035426888	DNA topoisomerase [Atopobium sp. ICM42b].	28.05	435	255	14	40	459	291	682	2e-31	138
rs:WP_016098187	DNA topoisomerase III [Bacillus cereus].	27.40	427	268	14	36	450	249	645	2e-31	137
rs:WP_047439881	DNA topoisomerase I [Chryseobacterium sp. YR561].	28.02	364	242	6	70	421	274	629	2e-31	137
rs:WP_005876033	topoisomerase [Enterococcus durans].	30.11	352	225	8	48	392	260	597	2e-31	137
rs:WP_037582686	DNA topoisomerase [Streptococcus anginosus].	32.42	364	219	10	37	397	180	519	2e-31	135
rs:WP_005609809	DNA topoisomerase III [Ruminococcus lactaris].	29.41	357	214	9	72	392	303	657	2e-31	137
rs:WP_024348418	DNA topoisomerase III [[Clostridium] methoxybenzovorans].	31.20	359	214	10	41	386	229	567	2e-31	137
rs:WP_021429852	DNA topoisomerase [[Clostridium] bifermentans].	26.22	431	262	11	47	450	247	648	2e-31	137
rs:WP_025161624	DNA topoisomerase [[Clostridium] bifermentans].	26.22	431	262	11	47	450	247	648	2e-31	137
rs:WP_007173277	DNA topoisomerase I [Prevotella bergensis].	30.67	313	201	6	74	384	276	574	2e-31	137
rs:WP_038694802	DNA topoisomerase I [Sphingobacterium sp. ML3W].	28.69	352	238	6	43	391	244	585	2e-31	137
rs:WP_012799454	DNA topoisomerase [Slackia heliotrinireducens].	29.40	432	257	14	38	459	286	679	2e-31	138
rs:WP_021666176	DNA topoisomerase [Porphyromonas sp. oral taxon 278].	28.30	417	267	13	17	425	216	608	2e-31	137
tr:K1US83_9ZZZZ	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EKC81125.1};	33.93	280	167	7	112	385	2	269	2e-31	134
tr:G6C564_9FUSO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHI77883.1};	26.93	401	263	8	43	425	253	641	2e-31	137
rs:WP_035114448	DNA topoisomerase [Clostridium sp. NCR].	26.22	431	262	11	47	450	247	648	2e-31	137
rs:WP_034545084	DNA topoisomerase [Clostridiales bacterium S7-1-4].	30.98	368	221	12	37	398	225	565	2e-31	136
rs:WP_000520753	hypothetical protein, partial [Bacillus cereus].	28.24	347	234	7	35	376	239	575	2e-31	136
rs:WP_016176677	DNA topoisomerase III [Enterococcus durans].	30.11	352	225	8	48	392	260	597	2e-31	137
tr:F3QUZ7_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EGG53247.1};	30.16	368	238	7	61	427	264	613	2e-31	137
rs:WP_002376837	DNA topoisomerase [Enterococcus faecium].	27.18	401	271	7	44	437	256	642	2e-31	137
rs:WP_027130995	DNA topoisomerase [Gemella cuniculi].	32.05	365	217	12	37	396	227	565	2e-31	135
rs:WP_009218765	DNA topoisomerase III [Lachnospiraceae oral taxon 107].	31.97	366	220	12	37	398	225	565	2e-31	135
rs:WP_036876890	DNA topoisomerase [Prevotella denticola].	28.16	412	266	11	22	426	18	406	2e-31	135
rs:WP_035303104	hypothetical protein, partial [Clostridium sp. HGF2].	28.54	403	272	11	47	446	234	623	2e-31	136
rs:WP_021388935	DNA topoisomerase, partial [Peptoclostridium difficile].	32.69	312	189	10	40	342	228	527	2e-31	135
rs:WP_036868535	MULTISPECIES: DNA topoisomerase I [Porphyromonas].	28.69	373	242	10	59	427	259	611	2e-31	137
tr:W4RI44_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE43578.1};	33.33	240	149	3	163	400	4	234	2e-31	131
tr:E6J286_STRAP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.42	364	219	10	37	397	186	525	2e-31	135
rs:WP_025477253	DNA topoisomerase [Enterococcus faecium].	27.95	390	256	9	57	437	269	642	2e-31	137
rs:WP_035495790	DNA topoisomerase [Fusobacterium sp. oral taxon 370].	26.93	401	263	8	43	425	239	627	2e-31	137
rs:WP_002299737	DNA topoisomerase [Enterococcus faecium].	27.86	402	257	11	44	427	256	642	2e-31	137
rs:WP_031554387	DNA topoisomerase III, partial [Oribacterium sp. FC2011].	28.04	378	232	11	61	401	294	668	2e-31	137
rs:WP_044666441	DNA topoisomerase [Streptococcus suis].	31.11	360	222	9	42	398	231	567	2e-31	135
rs:WP_022173204	DNA topoisomerase [Blautia sp. CAG:52].	30.59	353	211	12	72	397	319	664	2e-31	137
rs:WP_002843605	DNA topoisomerase III [Peptostreptococcus anaerobius].	31.87	364	221	11	37	397	225	564	2e-31	135
sp:TOP1_PYRHO	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	27.43	463	248	16	25	457	238	642	2e-31	137
rs:WP_033168144	DNA topoisomerase III [Clostridium sp. KNHs205].	29.09	361	224	12	61	392	312	669	2e-31	137
rs:WP_004384681	DNA topoisomerase I [Prevotella veroralis].	29.78	356	223	9	74	425	276	608	3e-31	137
rs:WP_007884408	DNA topoisomerase III [Roseburia inulinivorans].	29.17	408	260	10	47	445	235	622	3e-31	137
rs:WP_032581436	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	30.16	368	238	7	61	427	263	612	3e-31	137
rs:WP_047185446	DNA topoisomerase [Bacilli bacterium VT-13-104].	26.89	424	275	12	38	450	251	650	3e-31	137
rs:WP_040185591	DNA topoisomerase III, partial [Klebsiella pneumoniae].	30.11	269	169	5	188	443	1	263	3e-31	132
rs:WP_010776544	DNA topoisomerase III [Enterococcus faecium].	27.86	402	257	11	44	427	256	642	3e-31	137
rs:WP_010778097	DNA topoisomerase III [Enterococcus faecium].	27.86	402	257	11	44	427	256	642	3e-31	137
tr:F0H7Y1_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EGC86078.1};	28.16	412	266	11	22	426	28	416	3e-31	135
rs:WP_042223993	DNA topoisomerase [Oceanobacillus manasiensis].	28.61	402	255	14	40	429	253	634	3e-31	137
rs:WP_002838913	DNA topoisomerase III [Finegoldia magna].	30.79	367	223	11	37	398	225	565	3e-31	135
tr:A0A0A8VZ19_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.45	355	230	8	47	396	247	582	3e-31	137
rs:WP_006627218	DNA topoisomerase [Bulleidia extructa].	31.42	366	218	11	37	396	225	563	3e-31	135
rs:WP_012457618	DNA topoisomerase I [Porphyromonas gingivalis].	30.27	337	218	9	59	391	259	582	3e-31	137
rs:WP_004611672	hypothetical protein [Tyzzerella nexilis].	28.05	385	261	7	47	426	235	608	3e-31	137
tr:L2JM52_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.93	401	272	7	44	437	86	472	3e-31	135
tr:A0A0C7H255_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.45	355	230	8	47	396	247	582	3e-31	137
rs:WP_046041454	topoisomerase I [Lactobacillus plantarum].	29.11	450	273	15	29	454	237	664	3e-31	137
tr:C9C9G9_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.93	401	272	7	44	437	173	559	3e-31	136
rs:WP_007838676	DNA topoisomerase I [Bacteroides dorei].	30.68	352	220	9	56	400	258	592	3e-31	137
rs:WP_011107114	DNA topoisomerase I [Bacteroides thetaiotaomicron].	30.32	343	222	9	60	398	260	589	3e-31	137
rs:WP_004030988	DNA topoisomerase I [Methanobacterium formicicum].	29.49	451	254	20	18	453	219	620	3e-31	137
rs:WP_003029074	MULTISPECIES: DNA topoisomerase III [Streptococcus].	32.00	375	227	12	27	397	214	564	3e-31	135
rs:WP_044271898	DNA topoisomerase I [Candidatus Bacteroides timonensis].	29.62	368	238	11	62	427	265	613	3e-31	137
rs:WP_000366639	DNA topoisomerase [Streptococcus agalactiae].	32.23	363	219	10	37	396	225	563	3e-31	135
rs:WP_027870499	DNA topoisomerase III [[Eubacterium] cellulosolvens].	31.59	364	203	12	72	392	300	660	3e-31	137
tr:J6CXX6_PASMD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.60	277	180	5	5	280	238	500	3e-31	135
rs:WP_018395281	DNA topoisomerase [Bacillus sp. 37MA].	27.66	441	252	15	38	450	252	653	3e-31	137
rs:WP_030061483	MULTISPECIES: DNA topoisomerase III [Staphylococcus].	26.17	428	279	12	35	454	248	646	3e-31	137
rs:WP_005956640	DNA topoisomerase III [Peptoniphilus harei].	30.25	367	225	10	37	398	225	565	3e-31	135
rs:WP_022765397	DNA topoisomerase III [Butyrivibrio sp. XPD2006].	29.74	390	229	13	47	393	272	659	3e-31	136
rs:WP_040976237	DNA topoisomerase [Pasteurella sp. FF6].	32.42	364	219	10	37	397	225	564	3e-31	135
rs:WP_042742987	DNA topoisomerase III, partial [Staphylococcus aureus].	29.21	291	182	5	35	317	227	501	3e-31	135
tr:C7X9U5_9PORP	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEU51022.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EEU51022.1};	30.45	358	230	6	71	427	236	575	3e-31	136
rs:WP_041992690	hypothetical protein [Capnocytophaga cynodegmi].	28.57	357	244	9	41	394	241	589	3e-31	136
rs:WP_002328427	DNA topoisomerase III [Enterococcus faecium].	26.93	401	272	7	44	437	256	642	4e-31	137
rs:WP_046822078	DNA topoisomerase [Clostridium sp. JC272].	26.45	431	261	11	47	450	247	648	4e-31	137
rs:WP_043902904	DNA topoisomerase [Enterococcus faecium].	26.93	401	272	7	44	437	256	642	4e-31	137
rs:WP_032594315	DNA topoisomerase I [Bacteroides fragilis].	29.69	384	250	8	45	427	247	611	4e-31	136
tr:E4LQP4_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.54	403	272	11	47	446	234	623	4e-31	136
rs:WP_034276053	DNA topoisomerase III, partial [Bacillus sp. 171095_106].	33.22	304	170	10	167	453	2	289	4e-31	132
tr:C9B5N6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.93	401	272	7	44	437	186	572	4e-31	136
rs:WP_002336984	DNA topoisomerase III [Enterococcus faecium].	27.86	402	257	11	44	427	256	642	4e-31	137
tr:A0A015WCI0_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EXZ05162.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EXZ05162.1};	29.69	384	250	8	45	427	248	612	4e-31	136
rs:WP_026651907	DNA topoisomerase III [Butyrivibrio proteoclasticus].	28.84	423	223	14	40	400	274	680	4e-31	136
rs:WP_032945967	DNA topoisomerase I [Bacteroides vulgatus].	28.40	412	267	11	24	427	225	616	4e-31	136
rs:WP_029140971	DNA topoisomerase III [Streptococcus agalactiae].	31.59	364	222	11	37	397	225	564	4e-31	135
rs:WP_004832505	DNA topoisomerase [Parvimonas micra].	32.23	363	219	11	37	396	225	563	4e-31	135
rs:WP_000366636	DNA topoisomerase [Streptococcus agalactiae].	31.68	363	221	10	37	396	225	563	4e-31	135
rs:WP_036632665	DNA topoisomerase I [Parabacteroides distasonis].	29.62	368	240	7	61	427	263	612	5e-31	136
rs:WP_006844378	DNA topoisomerase I [Dysgonomonas mossii].	30.03	333	222	7	60	391	263	585	5e-31	136
tr:C2BCN7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.27	371	216	13	37	398	93	433	5e-31	134
rs:WP_021432150	DNA topoisomerase [[Clostridium] bifermentans].	26.22	431	262	11	47	450	247	648	5e-31	136
tr:A0A078TLV2_9PORP	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:KDS74932.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KDS74932.1};	29.62	368	240	7	61	427	264	613	5e-31	136
rs:WP_044300564	DNA topoisomerase I [Bacteroides fragilis].	29.94	354	231	9	60	409	260	600	5e-31	136
rs:WP_015062157	DNA topoisomerase III [Salmonella sp. 14].	29.60	250	170	2	23	271	236	480	5e-31	134
rs:WP_029949204	DNA topoisomerase [Parvimonas micra].	31.68	363	221	10	37	396	225	563	5e-31	135
rs:WP_001631999	DNA topoisomerase III [Staphylococcus aureus].	27.99	343	228	9	59	396	266	594	5e-31	136
rs:WP_040765487	DNA topoisomerase III, partial [Sutterella parvirubra].	29.77	346	198	9	98	425	4	322	5e-31	134
rs:WP_012655857	hypothetical protein [Macrococcus caseolyticus].	29.68	401	249	13	58	444	269	650	5e-31	136
rs:WP_002337695	DNA topoisomerase III [Enterococcus faecium].	26.93	401	272	7	44	437	256	642	5e-31	136
gp:CP002165_2004	DNA topoisomerase [Xylella fastidiosa subsp. fastidiosa GB514]	66.67	90	30	0	29	118	203	292	5e-31	131
rs:WP_005945111	DNA topoisomerase, partial [Faecalibacterium prausnitzii].	30.86	337	208	8	34	361	138	458	5e-31	134
rs:WP_040221470	DNA topoisomerase [Collinsella sp. MS5].	27.27	429	256	11	40	454	288	674	5e-31	137
rs:WP_047926353	DNA topoisomerase [Pasteurella multocida].	31.68	363	221	11	37	396	225	563	5e-31	135
rs:WP_040883080	DNA topoisomerase [Johnsonella ignava].	32.15	367	218	12	37	398	221	561	5e-31	134
rs:WP_025477629	DNA topoisomerase [Enterococcus faecium].	27.54	403	267	9	44	437	256	642	5e-31	136
rs:WP_004819943	DNA topoisomerase III [Peptoniphilus indolicus].	31.59	364	222	11	37	397	225	564	5e-31	135
tr:A0A078R730_BACVU	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:KDS29757.1};	28.40	412	267	11	24	427	227	618	5e-31	136
rs:WP_044679057	DNA topoisomerase [Streptococcus suis].	32.05	365	217	12	37	396	225	563	5e-31	134
rs:WP_029593788	DNA topoisomerase [Enterococcus faecium].	26.93	401	272	7	44	437	256	642	6e-31	136
rs:WP_032825815	DNA topoisomerase III, partial [Haemophilus haemolyticus].	40.12	162	96	1	36	197	260	420	6e-31	133
tr:G5GKW0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.15	367	218	12	37	398	242	582	6e-31	135
rs:WP_002341464	DNA topoisomerase III [Enterococcus faecium].	26.93	401	272	7	44	437	256	642	6e-31	136
rs:WP_032582746	DNA topoisomerase I, partial [Bacteroides fragilis].	29.03	372	240	10	60	427	135	486	6e-31	134
rs:WP_024379017	DNA topoisomerase [Streptococcus suis].	32.60	365	215	12	37	396	225	563	6e-31	134
rs:WP_042744647	DNA topoisomerase III, partial [Staphylococcus aureus].	27.99	343	228	9	59	396	266	594	6e-31	135
tr:A0A078QAC8_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:KDS20329.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KDS20329.1};	30.73	371	232	9	61	427	264	613	6e-31	136
rs:WP_002322737	DNA topoisomerase [Enterococcus faecium].	26.93	401	272	7	44	437	256	642	6e-31	136
rs:WP_000779853	DNA topoisomerase III [Streptococcus agalactiae].	31.87	364	221	11	37	397	225	564	6e-31	134
rs:WP_025476753	DNA topoisomerase [Enterococcus faecium].	26.93	401	272	7	44	437	256	642	6e-31	136
rs:WP_021979974	DNA topoisomerase III [Paraprevotella clara CAG:116].	29.89	358	226	10	60	409	260	600	6e-31	135
rs:WP_032529718	DNA topoisomerase I [Bacteroides fragilis].	29.66	354	232	9	60	409	260	600	6e-31	135
rs:WP_032532245	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	30.73	371	232	9	61	427	263	612	6e-31	136
rs:WP_004367624	DNA topoisomerase TopB, partial [Prevotella nigrescens].	29.21	356	225	9	74	425	160	492	6e-31	134
rs:WP_010727770	DNA topoisomerase III [Enterococcus faecium].	26.93	401	272	7	44	437	256	642	6e-31	136
rs:WP_010829678	DNA topoisomerase III [Enterococcus faecium].	26.93	401	272	7	44	437	256	642	6e-31	136
rs:WP_036868643	DNA topoisomerase I [Porphyromonas canoris].	30.25	314	202	6	74	384	276	575	6e-31	135
rs:WP_025481902	DNA topoisomerase [Enterococcus faecium].	26.93	401	272	7	44	437	256	642	6e-31	136
rs:WP_036764969	DNA topoisomerase [Peptostreptococcus sp. MV1].	31.87	364	221	11	37	397	225	564	6e-31	134
tr:E1YNZ2_9PORP	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFK64041.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFK64041.1};	30.05	376	234	12	60	427	262	616	6e-31	135
rs:WP_042994340	DNA topoisomerase I [Bacteroides fragilis].	30.73	371	232	9	61	427	263	612	6e-31	135
rs:WP_003038090	DNA topoisomerase [Streptococcus anginosus].	31.78	365	222	10	37	398	226	566	6e-31	134
rs:WP_035450702	DNA topoisomerase III [Lactobacillus composti].	26.59	410	261	8	40	449	235	604	6e-31	135
rs:WP_002333268	MULTISPECIES: DNA topoisomerase [Enterococcus].	26.93	401	272	7	44	437	256	642	6e-31	136
rs:WP_024566642	DNA topoisomerase I [Elizabethkingia anophelis].	28.41	345	236	5	48	391	250	584	6e-31	135
tr:S4F4D5_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.93	401	272	7	44	437	315	701	6e-31	136
rs:WP_042385891	DNA topoisomerase III [Geobacillus thermoglucosidasius].	26.52	396	255	12	74	454	282	656	7e-31	135
rs:WP_002327915	DNA topoisomerase III [Enterococcus faecium].	26.93	401	272	7	44	437	256	642	7e-31	136
rs:WP_036846849	MULTISPECIES: DNA topoisomerase I [Porphyromonas].	30.25	314	202	6	74	384	276	575	7e-31	135
tr:K6AE20_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKN21946.1};	30.73	371	232	9	61	427	264	613	7e-31	135
tr:A0A0E9F344_CHLTH	SubName: Full=DNA topoisomerase I-fused to SWI domain {ECO:0000313|EMBL:CRH76919.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRH76919.1};	31.87	364	221	11	37	397	11	350	7e-31	132
rs:WP_012809178	DNA topoisomerase [Atopobium parvulum].	27.59	435	257	14	40	459	291	682	7e-31	136
rs:WP_008766823	DNA topoisomerase I [Bacteroides sp. 1_1_6].	29.94	354	231	9	60	409	260	600	7e-31	135
tr:F9GLD9_HAEHA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	40.12	162	96	1	36	197	260	420	7e-31	134
rs:WP_023926441	hypothetical protein [Prevotella nigrescens].	27.97	354	232	9	74	425	276	608	7e-31	135
tr:D7INW6_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFI09104.1};	30.32	376	233	12	60	427	262	616	7e-31	135
rs:WP_034530141	DNA topoisomerase I [Parabacteroides sp. 20_3].	30.05	376	234	12	60	427	285	639	7e-31	136
rs:WP_002139803	DNA topoisomerase I [Bacillus cereus].	26.46	427	292	12	35	454	239	650	7e-31	136
rs:WP_012678206	DNA topoisomerase [Streptococcus equi].	30.85	363	224	10	37	396	225	563	7e-31	134
rs:WP_002296700	DNA topoisomerase [Enterococcus faecium].	26.93	401	272	7	44	437	315	701	7e-31	136
rs:WP_009276709	MULTISPECIES: DNA topoisomerase I [Parabacteroides].	29.95	394	246	13	43	427	267	639	7e-31	135
rs:WP_034675203	DNA topoisomerase I [Chryseobacterium formosense].	27.95	365	239	8	70	421	274	627	7e-31	135
rs:WP_002327040	DNA topoisomerase III [Enterococcus faecium].	26.93	401	272	7	44	437	256	642	7e-31	136
rs:WP_043902498	DNA topoisomerase [Enterococcus faecium].	26.93	401	272	7	44	437	256	642	7e-31	136
rs:WP_042853333	DNA topoisomerase III [Staphylococcus aureus].	27.99	343	228	9	59	396	266	594	7e-31	135
rs:WP_010992404	DNA topoisomerase I [Bacteroides fragilis].	29.94	354	231	9	60	409	260	600	7e-31	135
rs:WP_047478929	DNA topoisomerase I [Chryseobacterium sp. CF356].	28.41	345	234	5	48	391	250	582	7e-31	135
rs:WP_008513449	DNA topoisomerase III [Mucilaginibacter paludis].	29.91	331	213	11	57	382	265	581	8e-31	135
rs:WP_012816538	DNA topoisomerase III [Staphylococcus aureus].	27.99	343	228	9	59	396	266	594	8e-31	135
rs:WP_029427372	DNA topoisomerase I [Bacteroides cellulosilyticus].	31.18	356	219	9	61	404	263	604	8e-31	135
rs:WP_031919412	DNA topoisomerase III [Staphylococcus aureus].	27.99	343	228	9	59	396	266	594	8e-31	135
rs:WP_018910666	DNA topoisomerase I [Prevotella veroralis].	28.65	370	240	10	60	426	262	610	8e-31	135
rs:WP_031906002	DNA topoisomerase III [Staphylococcus aureus].	27.99	343	228	9	59	396	266	594	8e-31	135
tr:L2HCI8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.68	401	273	7	44	437	48	434	8e-31	134
rs:WP_031902829	DNA topoisomerase III [Staphylococcus aureus].	27.99	343	228	9	59	396	266	594	8e-31	135
rs:WP_002340635	DNA topoisomerase III [Enterococcus faecium].	27.95	390	256	9	57	437	269	642	8e-31	135
rs:WP_006525975	DNA topoisomerase [Solobacterium moorei].	31.68	363	221	11	37	396	225	563	8e-31	134
rs:WP_009012816	DNA topoisomerase I [Prevotella sp. C561].	32.06	315	194	7	74	384	276	574	9e-31	135
rs:WP_002340047	DNA topoisomerase III [Enterococcus faecium].	26.93	401	272	7	44	437	256	642	9e-31	135
rs:WP_043037586	DNA topoisomerase, partial [Streptococcus equi].	32.04	362	215	12	37	393	225	560	9e-31	134
rs:WP_007365528	DNA topoisomerase I [Porphyromonas uenonis].	31.82	308	191	7	74	378	276	567	9e-31	135
rs:WP_002244206	DNA topoisomerase [Neisseria meningitidis].	27.16	405	235	10	74	443	262	641	9e-31	136
rs:WP_005467933	DNA topoisomerase [Porphyromonas catoniae].	30.53	357	219	11	74	425	276	608	9e-31	135
rs:WP_002846237	DNA topoisomerase III [Peptostreptococcus anaerobius].	31.59	364	222	11	37	397	225	564	9e-31	134
rs:WP_005644270	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	30.32	376	233	12	60	427	285	639	9e-31	135
rs:WP_000859496	DNA topoisomerase III [Staphylococcus aureus].	27.99	343	228	9	59	396	266	594	9e-31	135
rs:WP_031867296	DNA topoisomerase III [Staphylococcus aureus].	27.99	343	228	9	59	396	266	594	9e-31	135
rs:WP_004820017	DNA topoisomerase [Peptoniphilus indolicus].	32.23	363	219	11	37	396	225	563	9e-31	134
rs:WP_027105433	DNA topoisomerase III [Lachnospiraceae bacterium V9D3004].	29.95	394	216	14	58	396	327	715	1e-30	135
rs:WP_004349950	DNA topoisomerase I [Prevotella buccalis].	29.48	329	212	7	60	384	262	574	1e-30	135
rs:WP_005825426	DNA topoisomerase I [Bacteroides uniformis].	29.35	368	239	11	62	427	265	613	1e-30	135
rs:WP_018357839	DNA topoisomerase I [Porphyromonas levii].	31.82	308	191	7	74	378	276	567	1e-30	135
tr:A0A0E9FRF1_CHLTH	SubName: Full=DNA topoisomerase I-fused to SWI domain {ECO:0000313|EMBL:CRH85326.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRH85326.1};	28.15	373	250	11	37	398	37	402	1e-30	133
rs:WP_019117888	DNA topoisomerase III [Anaerococcus obesiensis].	32.05	365	219	12	37	397	225	564	1e-30	134
rs:WP_010728361	DNA topoisomerase III [Enterococcus faecium].	26.93	401	272	7	44	437	256	642	1e-30	135
rs:WP_042685532	DNA topoisomerase I [Methermicoccus shengliensis].	28.15	444	273	15	18	454	217	621	1e-30	135
rs:WP_021393351	DNA topoisomerase III [Peptoclostridium difficile].	31.54	371	226	11	27	393	214	560	1e-30	134
rs:WP_045116179	hypothetical protein [Plesiocystis pacifica].	28.61	367	237	7	47	397	278	635	1e-30	137
rs:WP_038281769	DNA topoisomerase III [[Clostridium] celerecrescens].	28.21	390	226	13	59	397	295	681	1e-30	135
tr:B2I572_XYLF2	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	66.67	90	30	0	29	118	225	314	1e-30	130
tr:A0A060HA84_XYLFS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	66.67	90	30	0	29	118	225	314	1e-30	130
rs:WP_002335714	DNA topoisomerase III [Enterococcus faecium].	27.95	390	256	9	57	437	269	642	1e-30	135
rs:WP_036869100	DNA topoisomerase I, partial [Prevotella bivia].	29.88	328	212	8	60	384	66	378	1e-30	133
rs:WP_044145021	DNA topoisomerase [Enterococcus faecium].	27.06	388	262	7	57	437	269	642	1e-30	135
rs:WP_031864845	DNA topoisomerase III [Staphylococcus aureus].	27.99	343	228	9	59	396	266	594	1e-30	135
tr:A0A073IBB1_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KEJ86811.1};	30.17	358	231	6	71	427	274	613	1e-30	135
rs:WP_004318971	MULTISPECIES: DNA topoisomerase I [Bacteroides].	29.58	382	228	11	60	427	262	616	1e-30	135
rs:WP_044192291	DNA topoisomerase I [Parabacteroides gordonii].	29.62	368	240	7	61	427	249	598	1e-30	135
tr:A6G6C2_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.61	367	237	7	47	397	270	627	1e-30	136
rs:WP_005794610	DNA topoisomerase I [Bacteroides fragilis].	29.89	368	237	10	62	427	265	613	1e-30	135
rs:WP_004838439	DNA topoisomerase [Anaerococcus vaginalis].	30.52	367	224	11	37	398	225	565	1e-30	134
tr:J6CY98_PASMD	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJS91690.1}; Flags: Fragment;	40.61	165	90	2	161	325	1	157	1e-30	126
rs:WP_008901381	DNA topoisomerase [Peptoniphilus duerdenii].	29.97	367	226	10	37	398	225	565	1e-30	133
rs:WP_044192363	DNA topoisomerase I [Parabacteroides gordonii].	27.30	403	263	10	40	428	236	622	1e-30	135
tr:A0A0F5IPI4_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KKB47451.1};	29.62	368	240	7	61	427	245	594	1e-30	134
rs:WP_018968449	DNA topoisomerase I [Prevotella loescheii].	28.43	415	263	12	20	425	219	608	1e-30	135
rs:WP_004827735	DNA topoisomerase III [Anaerococcus lactolyticus].	31.59	364	222	11	37	397	225	564	1e-30	133
tr:A0A0F5JFZ5_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KKB56746.1};	27.30	403	263	10	40	428	222	608	1e-30	134
tr:Q2B124_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EAR63545.1};	28.83	333	205	6	104	434	1	303	1e-30	131
rs:WP_044736728	DNA topoisomerase III [Geobacillus kaustophilus].	26.95	397	252	13	74	454	282	656	1e-30	135
rs:WP_031906444	DNA topoisomerase III [Staphylococcus aureus].	27.99	343	228	9	59	396	266	594	1e-30	135
rs:WP_009906449	DNA topoisomerase III [Peptoclostridium difficile].	31.30	361	221	10	40	397	228	564	1e-30	133
rs:WP_026773238	DNA topoisomerase I [Sediminibacterium sp. OR43].	31.94	310	194	7	74	379	275	571	1e-30	134
rs:WP_041816684	DNA topoisomerase III, partial [Bacillus megaterium].	32.89	304	171	10	167	453	2	289	2e-30	130
rs:WP_044356176	DNA topoisomerase III, partial [Paenibacillus sp. E194].	32.68	257	144	4	186	435	4	238	2e-30	130
rs:WP_005834124	DNA topoisomerase I [Bacteroides uniformis].	27.30	403	263	10	40	428	250	636	2e-30	135
rs:WP_038230219	DNA topoisomerase, partial [Xylella fastidiosa].	65.93	91	31	0	29	119	245	335	2e-30	130
tr:I0TDW9_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EID33822.1};	32.29	288	169	8	79	360	1	268	2e-30	129
rs:WP_019117159	MULTISPECIES: DNA topoisomerase III [Clostridiales].	29.97	367	226	10	37	398	225	565	2e-30	133
rs:WP_009537698	DNA topoisomerase [Oribacterium asaccharolyticum].	32.23	363	219	11	37	396	225	563	2e-30	133
rs:WP_036764317	DNA topoisomerase [Peptostreptococcus sp. MV1].	29.97	367	226	10	37	398	225	565	2e-30	133
rs:WP_025883495	DNA topoisomerase I [Porphyromonas uenonis].	31.49	308	192	7	74	378	276	567	2e-30	134
rs:WP_004343312	MULTISPECIES: DNA topoisomerase I [Prevotellaceae].	29.49	356	224	9	74	425	286	618	2e-30	134
rs:WP_038231947	DNA topoisomerase, partial [Xylella fastidiosa].	65.93	91	31	0	29	119	245	335	2e-30	130
rs:WP_004364408	DNA topoisomerase III [Prevotella nigrescens].	28.93	356	226	9	74	425	276	608	2e-30	134
rs:WP_000779852	DNA topoisomerase III [Streptococcus agalactiae].	31.59	364	222	11	37	397	225	564	2e-30	133
rs:WP_021439520	DNA topoisomerase [Neisseria meningitidis].	26.91	405	236	10	74	443	262	641	2e-30	135
rs:WP_032533104	DNA topoisomerase I [Bacteroides fragilis].	29.03	372	240	10	60	427	260	611	2e-30	134
rs:WP_020999707	DNA topoisomerase III [Streptococcus anginosus].	31.59	364	222	11	37	397	225	564	2e-30	133
rs:WP_009009747	DNA topoisomerase [Coprobacillus sp. D7].	26.79	392	236	13	59	428	264	626	2e-30	135
rs:WP_036889370	DNA topoisomerase I [Porphyromonas crevioricanis].	30.25	314	202	6	74	384	276	575	2e-30	134
rs:WP_019107256	DNA topoisomerase III [Peptoniphilus senegalensis].	29.97	367	226	10	37	398	225	565	2e-30	133
rs:WP_018919957	DNA topoisomerase I [Prevotella oris].	29.53	359	222	11	74	425	276	610	2e-30	134
rs:WP_009228981	DNA topoisomerase I [Prevotella sp. oral taxon 299].	28.93	356	226	9	74	425	276	608	2e-30	134
rs:WP_043751848	DNA topoisomerase [Methylobacterium nodulans].	29.90	398	252	11	40	413	236	630	2e-30	135
rs:WP_012816503	DNA topoisomerase III [Staphylococcus aureus].	27.99	343	228	9	59	396	266	594	2e-30	134
rs:WP_006255415	DNA topoisomerase I [Alloprevotella tannerae].	30.09	329	210	7	60	384	262	574	2e-30	134
rs:WP_041954170	DNA topoisomerase [Parvimonas micra].	31.95	338	196	9	66	396	253	563	2e-30	133
tr:X6SVQ9_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.59	364	222	11	37	397	225	564	2e-30	133
rs:WP_031874414	DNA topoisomerase III [Staphylococcus aureus].	27.99	343	228	9	59	396	266	594	2e-30	134
rs:WP_010775606	DNA topoisomerase III [Enterococcus faecalis].	31.59	364	222	11	37	397	225	564	2e-30	133
rs:WP_036863984	MULTISPECIES: DNA topoisomerase I [Prevotella].	29.36	327	215	6	60	384	262	574	2e-30	134
tr:G5GKN4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.68	363	221	11	37	396	190	528	2e-30	132
rs:WP_002343287	DNA topoisomerase III [Enterococcus faecium].	26.68	401	273	7	44	437	256	642	2e-30	134
rs:WP_032843340	DNA topoisomerase I [Bacteroides ovatus].	30.73	371	232	9	61	427	263	612	2e-30	134
rs:WP_028896239	DNA topoisomerase I [Prevotella sp. HUN102].	30.50	341	225	7	56	393	258	589	2e-30	134
tr:B8IEL1_METNO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.90	398	252	11	40	413	245	639	2e-30	135
rs:WP_038100411	DNA topoisomerase III [Vagococcus lutrae].	27.36	424	253	11	34	445	188	568	2e-30	134
rs:WP_048098011	topoisomerase I [Candidatus Methanomethylophilus alvus].	27.52	436	264	13	34	458	233	627	2e-30	135
rs:WP_032948782	DNA topoisomerase I [Bacteroides vulgatus].	28.16	412	268	11	24	427	225	616	2e-30	134
rs:WP_036887964	DNA topoisomerase I [Prevotella bivia].	30.18	328	211	8	60	384	262	574	2e-30	134
rs:WP_040982951	DNA topoisomerase [Oceanobacillus sp. S5].	28.01	407	254	11	53	446	267	647	2e-30	134
rs:WP_007516585	DNA topoisomerase III [Streptococcus tigurinus].	30.85	363	224	11	37	396	225	563	2e-30	133
rs:WP_026504840	DNA topoisomerase III [Butyrivibrio sp. NC3005].	28.23	372	233	9	47	396	235	594	2e-30	133
rs:WP_022532720	DNA topoisomerase [Methanoculleus sp. CAG:1088].	27.52	436	264	13	34	458	234	628	2e-30	135
rs:WP_004331500	DNA topoisomerase I [Porphyromonas asaccharolytica].	31.49	308	192	7	74	378	276	567	2e-30	134
rs:WP_021485677	DNA topoisomerase III [Vibrio parahaemolyticus].	28.51	442	256	15	19	414	274	701	2e-30	135
rs:WP_015505040	DNA topoisomerase I [Candidatus Methanomethylophilus alvus].	27.52	436	264	13	34	458	234	628	2e-30	135
rs:WP_029730844	DNA topoisomerase III [Dorea sp. AGR2135].	29.36	361	234	7	37	385	220	571	2e-30	134
tr:I5AS62_EUBCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.29	373	224	11	47	396	235	594	2e-30	133
rs:WP_021422759	DNA topoisomerase III family protein [Peptoclostridium difficile].	31.68	363	221	11	37	396	225	563	2e-30	133
tr:V6Q728_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.36	424	253	11	34	445	222	602	2e-30	134
rs:WP_008515661	DNA topoisomerase I, archaeal [Methanobacterium sp. Maddingley MBC34].	29.27	451	255	20	18	453	219	620	2e-30	134
rs:WP_021434765	DNA topoisomerase III family protein [Peptoclostridium difficile].	31.68	363	221	11	37	396	225	563	2e-30	132
rs:WP_009893975	MULTISPECIES: DNA topoisomerase [Firmicutes].	31.68	363	221	11	37	396	225	563	3e-30	132
rs:WP_021371256	DNA topoisomerase III family protein [Peptoclostridium difficile].	31.68	363	221	11	37	396	225	563	3e-30	132
rs:WP_006723677	DNA topoisomerase [Collinsella intestinalis].	27.74	429	254	11	40	454	288	674	3e-30	135
tr:Z2EZT6_VIBPH	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EVU20835.1};	39.62	159	96	0	246	404	3	161	3e-30	126
rs:WP_007665500	DNA topoisomerase I [Bacteroides intestinalis].	30.17	358	225	9	60	409	260	600	3e-30	134
rs:WP_044976020	DNA topoisomerase III, partial [[Eubacterium] cellulosolvens].	30.29	373	224	11	47	396	235	594	3e-30	133
rs:WP_022474363	DNA topoisomerase III [Ruminococcus sp. CAG:353].	26.34	391	269	8	43	428	235	611	3e-30	134
rs:WP_023610339	DNA topoisomerase III [Streptococcus pyogenes].	31.87	364	221	11	37	397	225	564	3e-30	132
tr:T0U0C6_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	36.02	236	133	7	101	331	1	223	3e-30	127
rs:WP_007662652	DNA topoisomerase I [Bacteroides intestinalis].	30.90	288	184	7	65	350	268	542	3e-30	134
tr:T1AKL2_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD61116.1}; Flags: Fragment;	39.01	182	99	5	75	251	1	175	3e-30	126
rs:WP_010680147	DNA topoisomerase III [Fusobacterium gonidiaformans].	30.77	364	225	10	37	397	225	564	3e-30	132
rs:WP_009537904	MULTISPECIES: DNA topoisomerase [Lachnospiraceae].	31.68	363	221	11	37	396	225	563	3e-30	132
rs:WP_042742432	DNA topoisomerase III [Staphylococcus aureus].	27.70	343	229	9	59	396	266	594	3e-30	134
rs:WP_045495669	DNA topoisomerase I [Chryseobacterium sp. StRB126].	29.38	371	232	9	20	386	240	584	3e-30	134
rs:WP_036790611	DNA topoisomerase I [Porphyromonas canoris].	30.31	353	218	10	43	385	244	578	3e-30	134
rs:WP_015017147	MULTISPECIES: DNA topoisomerase III [Streptococcus].	31.59	364	222	11	37	397	225	564	3e-30	132
rs:WP_008675430	DNA topoisomerase I [Bacteroides sp. 9_1_42FAA].	29.08	368	242	6	61	427	264	613	3e-30	134
gpu:CP011228_1166	DNA topoisomerase [[Haemophilus] ducreyi]	31.39	360	220	11	40	396	228	563	3e-30	132
rs:WP_036421357	DNA topoisomerase III, partial [Morganella morganii].	32.03	231	153	1	37	267	245	471	3e-30	131
rs:WP_026624425	DNA topoisomerase [Eggerthia catenaformis].	31.68	363	221	11	37	396	225	563	3e-30	132
rs:WP_047656829	DNA topoisomerase III, partial [Salmonella enterica].	36.70	188	113	1	198	385	1	182	3e-30	127
rs:WP_047211463	DNA topoisomerase [Streptococcus agalactiae].	31.87	364	221	11	37	397	225	564	3e-30	132
rs:WP_034820565	DNA topoisomerase [[Eubacterium] nodatum].	31.96	363	220	11	37	396	225	563	3e-30	132
rs:WP_039680621	DNA topoisomerase [Terrisporobacter othiniensis].	28.29	357	228	9	47	396	249	584	3e-30	134
rs:WP_002989354	MULTISPECIES: DNA topoisomerase III [Streptococcus].	31.59	364	222	11	37	397	225	564	3e-30	132
rs:WP_005898479	DNA topoisomerase [Fusobacterium nucleatum].	24.76	424	289	8	40	448	236	644	4e-30	134
rs:WP_021625049	DNA topoisomerase [Atopobium sp. oral taxon 810].	28.41	440	251	14	38	459	293	686	4e-30	134
tr:K1TDW7_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central domain protein {ECO:0000313|EMBL:EKC57406.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EKC57406.1}; Flags: Fragment;	32.31	294	171	8	160	445	25	298	4e-30	129
rs:WP_019241916	DNA topoisomerase [Bacillus massilioanorexius].	26.81	429	271	13	36	450	249	648	4e-30	134
rs:WP_007845581	MULTISPECIES: DNA topoisomerase [Chryseobacterium].	27.08	373	248	7	20	391	240	589	4e-30	133
rs:WP_009644045	DNA topoisomerase III [Mogibacterium sp. CM50].	31.61	367	220	11	37	398	225	565	4e-30	132
rs:WP_018964968	DNA topoisomerase I [Porphyromonas gulae].	30.57	314	201	6	74	384	276	575	4e-30	133
rs:WP_010803751	MULTISPECIES: DNA topoisomerase III [Parabacteroides].	28.97	359	233	9	71	427	273	611	4e-30	133
rs:WP_033572507	DNA topoisomerase I [Bacteroides sp. UW].	29.19	394	257	8	37	427	238	612	4e-30	133
rs:WP_040609953	DNA topoisomerase III, partial [Salimicrobium jeotgali].	29.90	291	190	6	167	454	3	282	4e-30	129
rs:WP_005643615	DNA topoisomerase I [Parabacteroides merdae].	29.46	370	238	10	59	424	259	609	4e-30	133
gp:CP009031_2335	Topoisomerase IA [Xanthomonas citri subsp. citri]	31.97	244	150	5	218	454	7	241	4e-30	127
rs:WP_002318768	DNA topoisomerase [Enterococcus faecium].	26.68	401	273	7	44	437	256	642	4e-30	134
rs:WP_016274760	DNA topoisomerase III [Bacteroides massiliensis].	28.80	382	243	10	54	427	256	616	4e-30	133
rs:WP_025271989	DNA topoisomerase [Streptococcus anginosus].	31.01	358	220	10	43	397	231	564	4e-30	132
rs:WP_036894906	DNA topoisomerase I [Prevotella sp. S7-1-8].	29.36	327	215	6	60	384	262	574	4e-30	133
rs:WP_003031506	MULTISPECIES: DNA topoisomerase III [Streptococcus anginosus group].	31.65	357	215	11	37	389	225	556	5e-30	132
rs:WP_009132146	DNA topoisomerase III [Bacteroides oleiciplenus].	29.38	337	221	9	65	398	268	590	5e-30	133
rs:WP_042434696	DNA topoisomerase [Senegalimassilia anaerobia].	27.93	401	248	10	65	459	322	687	5e-30	134
rs:WP_000779859	MULTISPECIES: DNA topoisomerase III [Streptococcus].	31.32	364	223	11	37	397	225	564	5e-30	132
rs:WP_006906929	DNA topoisomerase III [Shuttleworthia satelles].	31.51	365	223	11	37	398	225	565	5e-30	132
rs:WP_047940425	DNA topoisomerase [Bacillus circulans].	29.34	409	252	14	54	450	266	649	5e-30	133
rs:WP_013708289	DNA topoisomerase [Coriobacterium glomerans].	28.44	429	251	11	40	454	287	673	5e-30	134
rs:WP_039446882	DNA topoisomerase I [Porphyromonas gulae].	28.37	356	231	9	74	426	276	610	5e-30	133
rs:WP_004303817	DNA topoisomerase I [Bacteroides ovatus].	30.90	288	184	7	65	350	268	542	5e-30	133
rs:WP_022583005	DNA topoisomerase III family protein [Peptoclostridium difficile].	31.40	363	222	11	37	396	225	563	5e-30	132
rs:WP_042971805	DNA topoisomerase I [Bacteroides fragilis].	30.90	288	184	7	65	350	268	542	5e-30	133
rs:WP_032597189	DNA topoisomerase I [Bacteroides fragilis].	30.90	288	184	7	65	350	268	542	5e-30	133
rs:WP_029485280	DNA topoisomerase [Enterococcus faecium].	27.18	401	271	7	44	437	256	642	5e-30	133
rs:WP_000366637	MULTISPECIES: DNA topoisomerase [Lactobacillales].	31.32	364	221	11	37	396	225	563	5e-30	132
rs:WP_016212888	DNA topoisomerase III [Parabacteroides goldsteinii].	30.90	288	184	7	65	350	268	542	6e-30	133
rs:WP_022455370	DNA topoisomerase I [Parabacteroides sp. CAG:409].	29.96	267	180	5	37	302	241	501	6e-30	131
rs:WP_024346744	DNA topoisomerase III [[Clostridium] methoxybenzovorans].	27.74	393	226	12	59	397	295	683	6e-30	133
rs:WP_034292903	DNA topoisomerase III [Alysiella crassa].	25.82	426	274	10	36	431	224	637	6e-30	133
rs:WP_033626145	DNA topoisomerase [Enterococcus faecalis].	31.10	373	225	12	31	398	220	565	6e-30	132
rs:WP_000779857	DNA topoisomerase III [Streptococcus agalactiae].	31.32	364	223	11	37	397	225	564	6e-30	131
rs:WP_002350833	DNA topoisomerase, partial [Enterococcus faecium].	33.21	271	166	6	98	365	2	260	6e-30	129
rs:WP_007894717	MULTISPECIES: DNA topoisomerase III [Firmicutes].	31.87	364	221	11	37	397	225	564	6e-30	131
tr:X2NB55_SALEN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	38.32	167	95	3	97	263	1	159	6e-30	124
rs:WP_015713669	DNA topoisomerase III [Bifidobacterium longum].	30.24	453	260	16	40	455	233	666	6e-30	133
tr:A4EC43_9ACTN	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.44	429	251	12	40	454	213	599	6e-30	133
rs:WP_012544366	DNA topoisomerase III [Coprothermobacter proteolyticus].	28.61	416	249	17	56	458	251	631	6e-30	132
rs:WP_003831767	DNA topoisomerase III [Bifidobacterium breve].	30.24	453	260	16	40	455	233	666	6e-30	133
rs:WP_031864418	DNA topoisomerase III [Staphylococcus aureus].	27.70	343	229	9	59	396	266	594	7e-30	133
rs:WP_016278636	DNA topoisomerase III [Bacteroides massiliensis].	27.83	406	265	13	47	436	248	641	7e-30	132
rs:WP_032849733	DNA topoisomerase I [Bacteroides sp. 2_2_4].	31.64	335	207	11	66	393	205	524	7e-30	132
rs:WP_031925419	DNA topoisomerase III [Staphylococcus aureus].	27.70	343	229	9	59	396	266	594	7e-30	132
rs:WP_005366709	DNA topoisomerase III [[Eubacterium] yurii].	31.15	366	219	12	37	396	225	563	7e-30	131
rs:WP_047200380	DNA topoisomerase [Streptococcus agalactiae].	31.59	364	222	11	37	397	225	564	7e-30	131
rs:WP_047641588	DNA topoisomerase, partial [Enterococcus faecium].	29.45	326	208	7	44	364	256	564	7e-30	131
rs:WP_013272546	DNA topoisomerase III [[Clostridium] saccharolyticum].	25.93	459	271	16	3	397	229	682	7e-30	132
rs:WP_024397233	DNA topoisomerase [Streptococcus suis].	31.40	363	222	11	37	396	225	563	7e-30	131
rs:WP_003150200	DNA topoisomerase [Atopobium rimae].	29.59	436	247	15	40	459	292	683	7e-30	133
rs:WP_020367711	hypothetical protein, partial [Staphylococcus epidermidis].	29.31	348	221	10	59	396	124	456	7e-30	130
rs:WP_010054218	DNA topoisomerase III [Carnobacterium maltaromaticum].	25.78	353	227	4	40	390	234	553	8e-30	132
rs:WP_020998778	DNA topoisomerase [Streptococcus intermedius].	31.40	363	222	11	37	396	225	563	8e-30	131
rs:WP_008153390	hypothetical protein, partial [Parabacteroides johnsonii].	33.95	271	161	7	60	329	86	339	8e-30	129
tr:D4V835_BACVU	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFG17986.1};	29.35	368	241	7	61	427	264	613	8e-30	132
rs:WP_037612753	DNA topoisomerase [Streptococcus sp. OBRC6].	31.51	365	223	11	37	398	225	565	8e-30	131
rs:WP_022348616	hypothetical protein [Collinsella sp. CAG:398].	26.81	429	258	11	40	454	290	676	8e-30	133
rs:WP_048042382	hypothetical protein, partial [Methanosarcina mazei].	32.37	241	153	5	160	396	22	256	8e-30	127
rs:WP_019128852	DNA topoisomerase [Enorma massiliensis].	26.81	429	258	11	40	454	290	676	8e-30	133
rs:WP_028897907	DNA topoisomerase I [Prevotella sp. HUN102].	29.25	359	232	9	71	427	273	611	8e-30	132
rs:WP_032938611	DNA topoisomerase I [Bacteroides vulgatus].	29.35	368	241	7	61	427	263	612	8e-30	132
rs:WP_029750153	DNA topoisomerase, partial [Streptococcus agalactiae].	31.40	363	222	11	37	396	11	349	9e-30	129
rs:WP_004352634	DNA topoisomerase I [Prevotella denticola].	29.10	354	228	8	74	425	276	608	9e-30	132
rs:WP_010724052	DNA topoisomerase III [Enterococcus faecium].	27.61	402	258	11	44	427	256	642	9e-30	132
rs:WP_016286472	DNA topoisomerase III [Lachnospiraceae bacterium 3-1].	26.82	399	236	13	50	395	278	673	9e-30	132
rs:WP_012376245	DNA topoisomerase [Opitutus terrae].	33.14	353	192	12	58	382	291	627	9e-30	133
rs:WP_037606927	DNA topoisomerase [Streptococcus sp. CM7].	30.41	365	227	10	37	398	227	567	9e-30	131
rs:WP_018371562	DNA topoisomerase [Streptococcus massiliensis].	31.96	363	220	10	37	396	225	563	9e-30	131
rs:WP_036381281	hypothetical protein [Mogibacterium timidum].	27.11	343	216	8	61	391	276	596	9e-30	132
tr:C3R196_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.64	335	207	11	66	393	223	542	9e-30	132
rs:WP_032496642	MULTISPECIES: DNA topoisomerase I [Bacteroides].	29.19	394	257	8	37	427	238	612	9e-30	132
rs:WP_044635092	DNA topoisomerase, partial [Treponema phagedenis].	30.85	363	224	11	37	396	17	355	1e-29	129
rs:WP_007895166	DNA topoisomerase III [Streptococcus pseudoporcinus].	30.68	365	226	11	37	398	227	567	1e-29	131
rs:WP_016203107	DNA topoisomerase [Bacillus nealsonii].	28.92	415	254	16	50	450	262	649	1e-29	132
rs:WP_000779855	DNA topoisomerase [Streptococcus pneumoniae].	32.19	351	203	11	37	380	225	547	1e-29	131
rs:WP_014791711	DNA topoisomerase [Ornithobacterium rhinotracheale].	28.22	326	225	6	61	385	263	580	1e-29	132
rs:WP_031935420	DNA topoisomerase III, partial [Escherichia coli].	42.28	149	84	2	36	184	220	366	1e-29	129
rs:WP_042533544	DNA topoisomerase [Oceanobacillus oncorhynchi].	27.05	403	261	10	36	425	252	634	1e-29	132
tr:F7LKF0_9BACE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGN04413.1};	29.19	394	257	8	37	427	239	613	1e-29	132
rs:WP_009222474	DNA topoisomerase III [Peptoniphilus sp. oral taxon 386].	30.89	369	220	10	37	398	227	567	1e-29	131
rs:WP_000779851	DNA topoisomerase III [Streptococcus agalactiae].	31.87	364	221	11	37	397	225	564	1e-29	131
rs:WP_025194606	DNA topoisomerase III [Streptococcus agalactiae].	30.41	365	227	10	37	398	227	567	1e-29	131
rs:WP_022450308	DNA topoisomerase [Roseburia sp. CAG:303].	31.45	337	197	13	90	396	2	334	1e-29	128
rs:WP_027640180	DNA topoisomerase [Clostridium cadaveris].	31.40	363	222	11	37	396	225	563	1e-29	130
rs:WP_040359782	DNA topoisomerase [Collinsella aerofaciens].	28.44	429	251	12	40	454	291	677	1e-29	132
rs:WP_022093857	DNA topoisomerase [Collinsella sp. CAG:166].	28.44	429	251	12	40	454	291	677	1e-29	132
rs:WP_006256385	DNA topoisomerase I [Alloprevotella tannerae].	29.05	358	225	9	74	425	286	620	1e-29	132
rs:WP_009300879	DNA topoisomerase [Coprobacillus sp. 3_3_56FAA].	26.23	385	234	12	66	428	270	626	1e-29	132
rs:WP_007895001	DNA topoisomerase III [Streptococcus pseudoporcinus].	30.33	366	221	10	40	398	228	566	1e-29	130
rs:WP_021663330	DNA topoisomerase [Porphyromonas gingivalis].	30.14	355	233	10	74	426	273	614	1e-29	132
rs:WP_044684362	DNA topoisomerase [Streptococcus suis].	31.23	365	220	11	37	396	225	563	1e-29	130
rs:WP_019036784	DNA topoisomerase I, partial [Prevotella amnii].	30.67	313	201	6	74	384	284	582	1e-29	131
tr:K5Y4M0_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKN08087.1};	29.35	368	241	7	61	427	264	613	1e-29	132
rs:WP_026713731	DNA topoisomerase I [Flavobacterium daejeonense].	27.33	344	238	6	43	384	244	577	1e-29	132
rs:WP_007895910	DNA topoisomerase III [Streptococcus pseudoporcinus].	30.05	366	222	10	40	398	228	566	1e-29	130
rs:WP_009140840	DNA topoisomerase [Collinsella tanakaei].	27.87	409	240	10	59	454	307	673	1e-29	132
rs:WP_034525879	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	29.35	368	241	7	61	427	263	612	1e-29	132
rs:WP_022525413	hypothetical protein [Streptococcus anginosus].	31.68	363	221	11	37	396	225	563	1e-29	130
rs:WP_003042371	DNA topoisomerase III [Streptococcus anginosus].	30.96	365	225	11	37	398	225	565	1e-29	130
rs:WP_004585380	DNA topoisomerase [Porphyromonas gingivalis].	29.86	355	234	10	74	426	273	614	1e-29	132
rs:WP_043052039	DNA topoisomerase [Streptococcus equi].	31.59	364	222	10	37	397	225	564	1e-29	130
rs:WP_032841868	DNA topoisomerase I [Bacteroides sp. 1_1_30].	29.92	371	235	9	61	427	263	612	1e-29	132
rs:WP_018675578	hypothetical protein [Riemerella columbina].	28.39	317	218	5	70	385	102	410	2e-29	130
rs:WP_026883648	DNA topoisomerase III [Clostridium akagii].	26.87	428	280	15	36	456	244	645	2e-29	132
rs:WP_018365297	DNA topoisomerase [Streptococcus caballi].	31.40	363	222	11	37	396	225	563	2e-29	130
rs:WP_035344579	DNA topoisomerase [Bacillus hemicellulosilyticus].	28.61	416	253	13	48	446	254	642	2e-29	132
rs:WP_015267011	topoisomerase IA [Echinicola vietnamensis].	28.78	337	221	6	74	401	277	603	2e-29	131
rs:WP_019239215	DNA topoisomerase [Collinsella sp. GD3].	26.81	429	258	11	40	454	287	673	2e-29	132
rs:WP_048317437	DNA topoisomerase I, partial [Parabacteroides goldsteinii].	30.56	288	185	7	65	350	268	542	2e-29	130
rs:WP_025143486	DNA topoisomerase III [Sphingobacterium sp. H1ai].	28.05	328	219	9	59	382	267	581	2e-29	131
rs:WP_047198600	DNA topoisomerase [Streptococcus agalactiae].	31.32	364	223	11	37	397	225	564	2e-29	130
rs:WP_034820457	DNA topoisomerase [[Eubacterium] nodatum].	31.47	340	199	9	66	398	253	565	2e-29	130
rs:WP_022370128	DNA topoisomerase type IA central domain protein [Eggerthella sp. CAG:368].	27.16	464	293	13	6	459	249	677	2e-29	132
tr:A0A0E9F656_CHLTH	SubName: Full=DNA topoisomerase I-fused to SWI domain {ECO:0000313|EMBL:CRH77593.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRH77593.1};	30.98	326	199	9	75	397	1	303	2e-29	127
rs:WP_007896555	DNA topoisomerase III [Streptococcus pseudoporcinus].	31.32	364	223	11	37	397	225	564	2e-29	130
rs:WP_041639327	DNA topoisomerase III, partial [Anoxybacillus flavithermus].	30.82	331	172	11	144	459	16	304	2e-29	128
rs:WP_044545931	DNA topoisomerase I, partial [Parabacteroides distasonis].	30.06	316	208	7	71	384	273	577	2e-29	130
rs:WP_025836956	DNA topoisomerase I [Prevotella scopos].	27.84	388	252	10	43	425	244	608	2e-29	131
rs:WP_012035064	DNA topoisomerase I [Methanocella arvoryzae].	26.38	436	247	14	40	454	237	619	2e-29	132
rs:WP_021348945	hypothetical protein [Elizabethkingia meningoseptica].	29.75	326	210	8	71	391	274	585	2e-29	131
tr:F7M0K7_9BACE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGN09098.1};	29.92	371	235	9	61	427	264	613	2e-29	131
rs:WP_013265186	DNA topoisomerase I [Prevotella melaninogenica].	29.21	356	220	10	79	425	278	610	2e-29	131
rs:WP_005800863	DNA topoisomerase I [Bacteroides fragilis].	30.36	336	217	9	67	398	267	589	2e-29	131
rs:WP_048198966	DNA topoisomerase I, partial [Methanocella arvoryzae].	26.38	436	247	14	40	454	237	619	2e-29	131
rs:WP_023059217	DNA topoisomerase III [Peptoniphilus sp. BV3AC2].	30.79	354	214	11	37	385	225	552	2e-29	130
rs:WP_039472425	DNA topoisomerase I [Pedobacter kyungheensis].	27.83	327	221	9	59	382	267	581	2e-29	130
rs:WP_029277927	DNA topoisomerase III [Pedobacter borealis].	27.98	336	209	9	59	382	267	581	2e-29	130
rs:WP_018697076	DNA topoisomerase I [Alistipes onderdonkii].	30.56	288	185	7	65	350	268	542	2e-29	131
rs:WP_045167309	DNA topoisomerase I [Prevotella intermedia].	29.33	358	218	9	74	426	276	603	2e-29	131
rs:WP_019034962	DNA topoisomerase III [Peptoniphilus lacrimalis].	30.25	367	225	11	37	398	225	565	2e-29	130
rs:WP_011861365	DNA topoisomerase [Peptoclostridium difficile].	30.13	375	234	10	27	397	214	564	2e-29	130
tr:A0A0B7H388_TREPH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.85	363	224	11	37	396	105	443	2e-29	129
rs:WP_010691817	DNA topoisomerase III [Treponema denticola].	30.32	310	191	7	56	357	257	549	2e-29	131
rs:WP_000779850	DNA topoisomerase III [Streptococcus agalactiae].	31.32	364	223	11	37	397	225	564	2e-29	130
rs:WP_023607195	DNA topoisomerase III, partial [Staphylococcus epidermidis].	30.37	326	204	9	59	376	271	581	2e-29	130
tr:K1SJ22_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC47331.1}; Flags: Fragment;	29.89	271	156	6	61	324	2	245	2e-29	125
tr:G0QFA3_NANS0	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.74	477	291	16	4	454	204	638	2e-29	131
rs:WP_006709842	DNA topoisomerase, partial [Serratia symbiotica].	36.76	204	124	4	98	300	2	201	2e-29	124
rs:WP_039920388	DNA topoisomerase [Anaerococcus vaginalis].	32.31	325	186	9	81	396	265	564	2e-29	130
rs:WP_038695639	DNA topoisomerase I [Sphingobacterium sp. ML3W].	27.27	396	262	11	46	427	247	630	2e-29	131
rs:WP_008620097	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	30.56	288	185	7	65	350	268	542	2e-29	131
rs:WP_005681364	MULTISPECIES: DNA topoisomerase I [Bacteroides].	30.56	288	185	7	65	350	268	542	2e-29	131
rs:WP_047211613	DNA topoisomerase [Streptococcus agalactiae].	31.38	325	189	9	81	396	265	564	2e-29	130
rs:WP_004338303	MULTISPECIES: DNA topoisomerase I [Prevotella].	29.57	328	213	8	60	384	262	574	3e-29	131
rs:WP_047386578	hypothetical protein, partial [Firmicutes bacterium ZOR0006].	28.37	423	255	12	47	452	246	637	3e-29	130
tr:C7HSY0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.31	325	186	9	81	396	269	568	3e-29	130
rs:WP_032558157	MULTISPECIES: DNA topoisomerase I [Bacteroides].	30.56	288	185	7	65	350	268	542	3e-29	131
rs:WP_019036208	MULTISPECIES: DNA topoisomerase I [Prevotella].	29.57	328	213	8	60	384	262	574	3e-29	131
rs:WP_048189667	DNA topoisomerase I [Methanocella conradii].	28.01	407	246	12	56	453	253	621	3e-29	130
rs:WP_008124769	DNA topoisomerase I [Prevotella timonensis].	29.66	327	214	6	60	384	262	574	3e-29	131
rs:WP_014406759	DNA topoisomerase I [Methanocella conradii].	28.01	407	246	12	56	453	271	639	3e-29	131
rs:WP_016526652	DNA topoisomerase [Lactobacillus plantarum].	29.95	374	239	8	29	393	237	596	3e-29	131
rs:WP_000366638	DNA topoisomerase [Streptococcus agalactiae].	31.04	364	222	11	37	396	225	563	3e-29	129
tr:T3QN90_PEPDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.73	357	225	10	47	396	96	426	3e-29	129
rs:WP_041013033	hypothetical protein [Vibrio sp. DCR 1-4-12].	38.99	159	97	0	246	404	3	161	3e-29	123
rs:WP_029491379	DNA topoisomerase [Fusobacterium hwasookii].	25.18	421	285	9	43	448	239	644	3e-29	131
rs:WP_031825907	DNA topoisomerase III, partial [Staphylococcus aureus].	26.49	370	251	7	57	423	268	619	3e-29	130
tr:A0A016FRT4_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EYA20988.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EYA20988.1};	28.93	394	258	8	37	427	239	613	3e-29	130
rs:WP_029216649	DNA topoisomerase I [Prevotella denticola].	28.24	386	245	10	45	426	246	603	3e-29	130
rs:WP_008441419	DNA topoisomerase I, archaeal [Thermoplasmatales archaeon SCGC AB-539-N05].	26.39	451	272	18	18	453	218	623	3e-29	130
rs:WP_032461281	DNA topoisomerase [Streptococcus pyogenes].	30.58	363	225	11	37	396	227	565	3e-29	129
rs:WP_031543238	DNA topoisomerase III, partial [Lachnospiraceae bacterium AC2014].	29.89	358	216	10	61	396	250	594	3e-29	130
rs:WP_026771463	DNA topoisomerase [Sediminibacillus halophilus].	27.68	419	261	13	46	450	262	652	3e-29	130
rs:WP_023260375	DNA topoisomerase III, partial [Salmonella enterica].	36.02	186	113	1	200	385	2	181	3e-29	124
tr:W4PNB6_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.06	360	235	9	71	427	226	564	4e-29	130
rs:WP_040227551	DNA topoisomerase III, partial [Bhargavaea cecembensis].	32.07	237	150	4	33	266	230	458	4e-29	128
rs:WP_044727511	DNA topoisomerase [Streptococcus pneumoniae].	31.60	326	191	8	81	398	265	566	4e-29	129
rs:WP_000779860	DNA topoisomerase III [Streptococcus agalactiae].	30.77	364	225	10	37	397	225	564	4e-29	129
rs:WP_039431396	DNA topoisomerase I [Porphyromonas gulae].	27.65	358	239	7	71	427	273	611	4e-29	130
rs:WP_009535407	DNA topoisomerase III [Oribacterium parvum].	31.27	371	223	12	31	396	220	563	4e-29	129
rs:WP_005747021	DNA topoisomerase III, partial [Pseudomonas amygdali].	41.18	153	88	2	31	181	222	374	4e-29	127
rs:WP_032532598	DNA topoisomerase I [Bacteroides fragilis].	28.93	394	258	8	37	427	238	612	4e-29	130
rs:WP_023992619	DNA topoisomerase 1 [Methanobacterium sp. MB1].	29.27	451	255	20	18	453	219	620	4e-29	130
rs:WP_025876744	DNA topoisomerase I [Prevotella corporis].	28.45	355	231	8	74	426	286	619	4e-29	130
rs:WP_009125918	DNA topoisomerase I [Bacteroides fluxus].	30.56	288	185	7	65	350	268	542	4e-29	130
rs:WP_028902015	DNA topoisomerase I [Prevotella corporis].	28.45	355	231	8	74	426	286	619	4e-29	130
rs:WP_047378326	DNA topoisomerase I [Chryseobacterium sp. YR459].	28.85	364	239	8	37	394	238	587	4e-29	130
rs:WP_013702783	DNA topoisomerase [Treponema succinifaciens].	27.27	352	230	9	53	398	256	587	4e-29	129
rs:WP_047199848	DNA topoisomerase [Streptococcus agalactiae].	31.69	325	188	9	81	396	265	564	4e-29	129
rs:WP_036857240	DNA topoisomerase I [Prevotella denticola].	30.00	360	221	9	74	425	284	620	4e-29	130
rs:WP_023036564	hypothetical protein [Fusobacterium nucleatum].	25.24	424	287	9	40	448	236	644	4e-29	130
rs:WP_009346275	DNA topoisomerase III [Peptoniphilus sp. oral taxon 836].	31.04	364	224	11	37	397	225	564	4e-29	129
rs:WP_034303584	DNA topoisomerase III, partial [Bacillus sp. 123MFChir2].	32.20	295	170	7	170	450	9	287	4e-29	126
rs:WP_028905786	DNA topoisomerase I [Prevotella intermedia].	30.57	314	194	7	74	384	276	568	4e-29	130
rs:WP_047716048	DNA topoisomerase [Streptococcus pyogenes].	30.58	363	225	11	37	396	227	565	4e-29	129
rs:WP_031436385	DNA topoisomerase [Methylobacter tundripaludum].	26.99	389	242	8	39	395	233	611	4e-29	130
rs:WP_036872634	DNA topoisomerase I [Porphyromonas macacae].	28.15	373	244	10	59	427	259	611	4e-29	130
rs:WP_006740590	DNA topoisomerase III [Streptococcus urinalis].	30.59	340	203	9	65	398	254	566	5e-29	129
rs:WP_036844649	DNA topoisomerase I [Porphyromonas sp. COT-108 OH1349].	27.65	358	239	7	71	427	273	611	5e-29	130
rs:WP_034564290	DNA topoisomerase III [Carnobacterium gallinarum].	25.27	372	241	5	18	385	210	548	5e-29	130
rs:WP_025188549	DNA topoisomerase [Enterococcus faecalis].	29.86	365	229	11	37	398	227	567	5e-29	129
rs:WP_009347068	DNA topoisomerase I [Alloprevotella rava].	29.07	375	233	13	22	384	221	574	5e-29	130
tr:J6BME1_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.86	365	229	11	37	398	263	603	5e-29	129
tr:E1JMD1_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.04	303	183	4	59	361	253	523	5e-29	128
rs:WP_024295612	MULTISPECIES: DNA topoisomerase III [Lachnoclostridium].	26.97	393	229	11	59	397	295	683	5e-29	130
rs:WP_021677873	DNA topoisomerase [Porphyromonas gingivalis].	28.95	342	225	7	47	384	248	575	5e-29	130
rs:WP_027952894	DNA topoisomerase I [Hallella seregens].	28.20	422	278	12	18	427	217	625	5e-29	130
rs:WP_046960678	hypothetical protein, partial [Escherichia coli].	54.46	101	42	2	358	458	1	97	5e-29	120
rs:WP_045754926	DNA topoisomerase I [Sphingobacterium sp. PM2-P1-29].	28.57	378	243	11	65	427	265	630	5e-29	130
rs:WP_002370359	DNA topoisomerase III, partial [Enterococcus faecalis].	31.02	245	152	2	47	290	243	471	5e-29	128
rs:WP_008564100	DNA topoisomerase I [Prevotella maculosa].	30.31	353	229	9	35	377	236	581	5e-29	130
rs:WP_010248082	DNA topoisomerase III [Peptoniphilus rhinitidis].	29.59	365	230	11	37	398	225	565	5e-29	129
rs:WP_041619455	DNA topoisomerase III, partial [Paenibacillus mucilaginosus].	38.18	220	120	6	34	246	228	438	5e-29	128
rs:WP_022184182	DNA topoisomerase type IA central domain protein [Eggerthella sp. CAG:209].	26.29	464	297	12	6	459	249	677	5e-29	130
tr:A0A0E9EDT1_CHLTH	SubName: Full=DNA topoisomerase I-fused to SWI domain {ECO:0000313|EMBL:CRH68123.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRH68123.1};	31.58	361	206	11	40	387	112	444	5e-29	127
tr:A0A0B8PSF8_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	41.01	139	82	0	32	170	32	170	5e-29	122
rs:WP_034440668	DNA topoisomerase [Clostridiales bacterium S5-A11].	31.59	364	222	11	37	397	225	564	6e-29	129
rs:WP_036856717	DNA topoisomerase I [Prevotella amnii].	29.48	329	212	8	60	384	262	574	6e-29	130
rs:WP_045167922	DNA topoisomerase I [Prevotella intermedia].	29.81	312	202	6	74	384	276	571	6e-29	130
rs:WP_026570600	DNA topoisomerase [Bacillus sp. NSP22.2].	27.83	406	255	12	59	450	271	652	6e-29	130
rs:WP_035779841	DNA topoisomerase III [Butyrivibrio sp. MC2013].	29.76	373	226	11	47	396	235	594	6e-29	129
rs:WP_040551369	DNA topoisomerase [Peptoniphilus duerdenii].	29.40	364	223	10	40	396	228	564	6e-29	129
tr:A0A0E4BIT9_TANFO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:BAR52507.1};	28.03	421	280	12	18	427	217	625	6e-29	130
rs:WP_048191331	DNA topoisomerase I [Methanobacterium sp. SMA-27].	28.57	427	248	17	39	453	245	626	6e-29	130
rs:WP_002643085	DNA topoisomerase III [Simonsiella muelleri].	27.97	354	220	8	70	396	258	603	6e-29	130
tr:W4RS51_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE46703.1};	29.43	299	174	6	143	434	9	277	6e-29	126
tr:A0A0B8PEW1_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.36	220	137	4	51	260	7	222	6e-29	124
tr:E0NMC4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.40	364	223	10	40	396	232	568	6e-29	129
rs:WP_034568898	DNA topoisomerase III [Carnobacterium divergens].	25.75	400	251	8	40	434	234	592	6e-29	130
rs:WP_010491173	topoisomerase IA, partial [Lactobacillus zeae].	33.48	230	141	4	170	397	8	227	7e-29	126
rs:WP_045168253	DNA topoisomerase I [Prevotella intermedia].	28.03	421	280	12	18	427	217	625	7e-29	130
tr:A0A015SDB8_BACFG	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EXY68292.1};	28.72	376	234	10	60	427	47	396	7e-29	127
rs:WP_043411915	DNA topoisomerase III, partial [Streptomyces pluripotens].	39.27	191	98	5	157	344	36	211	7e-29	123
rs:WP_002842318	DNA topoisomerase [Finegoldia magna].	30.51	354	215	11	37	385	225	552	7e-29	128
tr:X1LU46_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_C00382 {ECO:0000313|EMBL:GAH97648.1}; Flags: Fragment;	25.81	430	266	12	40	454	53	444	7e-29	128
rs:XP_004334075	DNA topoisomerase [Acanthamoeba castellanii str. Neff].	28.95	456	228	18	76	444	562	1008	8e-29	130
rs:WP_009430769	DNA topoisomerase III [Peptoniphilus sp. oral taxon 375].	30.59	340	203	9	65	398	254	566	8e-29	128
rs:WP_040397454	DNA topoisomerase [Anaerococcus senegalensis].	31.48	359	205	14	37	385	225	552	8e-29	128
rs:WP_039416653	DNA topoisomerase I [Porphyromonas gingivalis].	29.30	355	236	10	74	426	273	614	8e-29	129
rs:WP_009643973	DNA topoisomerase, partial [Mogibacterium sp. CM50].	32.34	334	200	10	66	396	2	312	8e-29	125
rs:WP_044564917	DNA topoisomerase [Anaerococcus sp. 9402080].	29.70	367	231	11	35	398	223	565	8e-29	128
rs:WP_004825718	DNA topoisomerase III [Peptoniphilus lacrimalis].	31.38	325	189	9	81	396	265	564	8e-29	128
rs:WP_000002937	DNA topoisomerase [Streptococcus agalactiae].	31.40	363	222	10	37	396	180	518	8e-29	128
rs:WP_047199997	DNA topoisomerase [Streptococcus agalactiae].	31.32	364	223	11	37	397	225	564	8e-29	128
rs:WP_036870016	DNA topoisomerase I [Prevotella histicola].	30.14	355	223	10	74	425	276	608	8e-29	129
rs:WP_015547215	DNA topoisomerase III, bacteria and conjugative plasmid [Alistipes shahii].	30.04	283	184	6	70	350	272	542	8e-29	129
rs:WP_048506290	DNA topoisomerase I [Chryseobacterium angstadtii].	28.73	362	221	11	74	424	276	611	9e-29	129
rs:WP_044159254	DNA topoisomerase I [Bacteroides reticulotermitis].	30.03	333	215	8	66	393	205	524	9e-29	129
rs:WP_012248288	hypothetical protein, partial [Bordetella petrii].	39.35	155	93	1	36	189	241	395	9e-29	126
rs:WP_040473085	topoisomerase I, partial [Lactobacillus coryniformis].	34.06	229	139	5	171	397	1	219	9e-29	125
rs:WP_034288249	DNA topoisomerase [Bacillus sp. 72].	27.61	431	245	15	48	450	262	653	9e-29	129
rs:WP_003033547	MULTISPECIES: DNA topoisomerase III [Bacteria].	31.40	363	222	10	37	396	225	563	1e-28	128
rs:WP_004319201	MULTISPECIES: DNA topoisomerase I [Bacteroides].	30.56	288	185	7	65	350	268	542	1e-28	129
tr:W1FC26_ENTCL	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CDL31348.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDL31348.1};	36.02	186	113	1	200	385	2	181	1e-28	122
rs:WP_004295480	DNA topoisomerase I [Bacteroides eggerthii].	30.56	288	185	7	65	350	268	542	1e-28	129
rs:WP_037567095	DNA topoisomerase III [Staphylococcus agnetis].	28.15	341	231	3	54	391	246	575	1e-28	129
rs:WP_007790064	DNA topoisomerase [Peptostreptococcus stomatis].	30.58	363	225	11	37	396	225	563	1e-28	128
rs:WP_024623473	DNA topoisomerase, partial [Streptococcus pyogenes].	30.08	369	223	11	37	398	32	372	1e-28	126
rs:WP_025892911	DNA topoisomerase I [Bacteroides barnesiae].	28.93	394	253	12	37	424	239	611	1e-28	129
rs:WP_031909704	DNA topoisomerase III, partial [Staphylococcus aureus].	28.78	278	176	4	35	306	227	488	1e-28	127
rs:WP_007392113	DNA topoisomerase [Megasphaera sp. UPII 135-E].	30.58	363	225	11	37	396	227	565	1e-28	128
rs:WP_048204947	DNA topoisomerase I [Methanococcoides methylutens].	27.29	414	250	14	51	454	252	624	1e-28	129
rs:WP_031806817	DNA topoisomerase III, partial [Staphylococcus aureus].	29.15	271	170	4	35	299	87	341	1e-28	125
rs:WP_034255094	DNA topoisomerase III [Bifidobacterium kashiwanohense].	31.00	400	230	13	40	405	233	620	1e-28	129
tr:W4UM81_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.03	333	215	8	66	393	220	539	1e-28	129
rs:WP_004584872	MULTISPECIES: DNA topoisomerase [Porphyromonadaceae].	28.03	371	243	8	74	443	286	633	1e-28	129
rs:WP_036929574	DNA topoisomerase I, partial [Prevotella timonensis].	28.79	389	249	10	43	426	244	609	1e-28	129
rs:WP_036681478	hypothetical protein [Paenibacillus sp. FSL H8-237].	25.06	411	286	8	36	432	239	641	1e-28	129
rs:WP_011448040	DNA topoisomerase I [Methanospirillum hungatei].	24.43	442	283	15	18	449	216	616	1e-28	129
tr:K1SY50_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central domain protein {ECO:0000313|EMBL:EKC65527.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EKC65527.1}; Flags: Fragment;	34.73	239	132	6	160	385	7	234	1e-28	122
rs:WP_035137691	DNA topoisomerase [Collinsella sp. 4_8_47FAA].	28.11	402	234	11	66	454	318	677	1e-28	129
rs:WP_004380945	DNA topoisomerase I [Prevotella oulorum].	29.14	374	233	11	79	443	278	628	1e-28	129
rs:WP_010815630	DNA topoisomerase III [Enterococcus faecalis].	31.79	324	189	10	81	396	265	564	1e-28	127
rs:WP_048072297	DNA topoisomerase I [Methanobacterium formicicum].	29.47	431	240	20	38	453	239	620	1e-28	129
rs:WP_005805288	MULTISPECIES: DNA topoisomerase I [Bacteroides].	28.72	376	234	10	60	427	206	555	1e-28	128
rs:WP_004360034	DNA topoisomerase I [Prevotella melaninogenica].	28.88	329	214	7	60	384	262	574	1e-28	129
rs:WP_003454290	DNA topoisomerase I [Pseudomonas pseudoalcaligenes].	26.51	498	254	19	32	459	220	675	2e-28	129
rs:WP_031786349	DNA topoisomerase III, partial [Staphylococcus aureus].	26.90	342	230	6	57	396	83	406	2e-28	125
rs:WP_006906961	DNA topoisomerase [Shuttleworthia satelles].	30.58	363	225	11	37	396	225	563	2e-28	127
rs:WP_032538771	DNA topoisomerase, partial [Peptoclostridium difficile].	29.87	375	235	10	27	397	191	541	2e-28	127
rs:WP_019118541	DNA topoisomerase III [Anaerococcus obesiensis].	30.77	325	191	9	81	396	265	564	2e-28	127
rs:WP_011405969	DNA topoisomerase I [Methanosphaera stadtmanae].	27.59	453	262	18	18	453	222	625	2e-28	129
rs:WP_032631661	DNA topoisomerase III, partial [Pseudomonas syringae].	37.57	181	104	2	106	280	2	179	2e-28	120
rs:WP_039931025	DNA topoisomerase [Anaerococcus lactolyticus].	31.08	325	190	9	81	396	265	564	2e-28	127
rs:WP_013816520	DNA topoisomerase I [Porphyromonas gingivalis].	29.30	355	236	10	74	426	273	614	2e-28	128
tr:C2BCS2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.08	325	190	9	81	396	269	568	2e-28	127
rs:WP_014215559	DNA topoisomerase III [Pediococcus claussenii].	26.15	390	249	9	47	434	242	594	2e-28	128
rs:WP_005552553	DNA topoisomerase 3 [Paenibacillus alvei].	26.70	412	251	9	47	424	256	650	2e-28	129
rs:WP_009229667	DNA topoisomerase I [Prevotella sp. oral taxon 317].	28.75	327	217	6	60	384	262	574	2e-28	128
rs:WP_017643941	DNA topoisomerase [Streptococcus agalactiae].	30.14	365	228	11	37	398	152	492	2e-28	126
rs:WP_032575310	DNA topoisomerase I [Bacteroides fragilis].	28.72	376	234	10	60	427	206	555	2e-28	128
rs:WP_046676093	DNA topoisomerase I [Sphingobacterium sp. Ag1].	30.09	319	208	8	74	390	276	581	2e-28	128
tr:V7Z0V9_LACPN	SubName: Full=Topoisomerase I {ECO:0000313|EMBL:ETC79988.1};	31.82	242	152	5	161	397	2	235	2e-28	124
tr:Q1J4U0_STRPF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.06	336	206	8	65	396	258	568	2e-28	127
rs:WP_023612253	DNA topoisomerase III [Streptococcus pyogenes].	30.14	365	228	11	37	398	227	567	2e-28	127
rs:WP_040152278	DNA topoisomerase III, partial [Xanthomonas citri].	39.13	161	91	2	36	192	72	229	2e-28	122
rs:WP_031894067	DNA topoisomerase III, partial [Staphylococcus aureus].	26.90	342	230	6	57	396	118	441	2e-28	126
rs:WP_028897449	DNA topoisomerase I [Prevotella sp. HUN102].	28.84	371	247	10	18	377	217	581	2e-28	128
rs:WP_048198984	DNA topoisomerase I, partial [Methanocella arvoryzae].	28.12	409	243	14	56	453	253	621	2e-28	128
rs:WP_044555099	DNA topoisomerase [Streptococcus pyogenes].	30.06	336	206	8	65	396	254	564	2e-28	127
rs:WP_039943978	DNA topoisomerase, partial [Treponema phagedenis].	32.04	334	201	10	66	396	106	416	2e-28	125
rs:WP_039677235	DNA topoisomerase [Streptococcus constellatus].	31.70	347	210	11	37	380	225	547	2e-28	127
rs:WP_016477303	DNA topoisomerase I [Atopobium sp. oral taxon 199].	29.16	439	245	15	40	459	292	683	2e-28	129
rs:WP_032459396	DNA topoisomerase III [Streptococcus agalactiae].	30.14	365	228	11	37	398	227	567	2e-28	127
rs:WP_036573498	DNA topoisomerase [Oceanobacillus picturae].	27.92	394	252	13	48	429	261	634	2e-28	128
rs:WP_009524905	DNA topoisomerase III [Peptostreptococcaceae bacterium ACC19a].	30.96	365	225	10	37	398	227	567	2e-28	127
rs:WP_041505349	DNA topoisomerase I [Sanguibacteroides justesenii].	28.11	370	246	10	60	427	262	613	2e-28	128
tr:Q19V32_HAEIF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	39.35	155	93	1	36	190	260	413	2e-28	125
rs:WP_010649676	DNA topoisomerase [Oceanobacillus massiliensis].	26.83	410	265	11	48	446	262	647	2e-28	128
rs:WP_016219894	DNA topoisomerase III [Dorea sp. 5-2].	29.57	416	257	13	43	445	231	623	2e-28	128
rs:WP_003426113	DNA topoisomerase III [Peptoclostridium difficile].	29.87	375	235	10	27	397	214	564	2e-28	127
rs:WP_032459628	DNA topoisomerase III [Streptococcus agalactiae].	30.14	365	228	11	37	398	227	567	3e-28	127
rs:WP_013826367	DNA topoisomerase I [Methanobacterium paludis].	28.97	428	247	17	38	453	244	626	3e-28	128
rs:WP_005800963	DNA topoisomerase I [Bacteroides fragilis].	28.11	370	246	10	60	427	262	613	3e-28	128
rs:WP_013701945	DNA topoisomerase III [Treponema succinifaciens].	26.87	402	257	13	56	446	251	626	3e-28	128
rs:WP_035112638	DNA topoisomerase [Finegoldia magna].	29.28	362	226	9	40	396	228	564	3e-28	127
rs:WP_042958334	DNA topoisomerase, partial [Enterococcus faecium].	31.47	340	202	11	37	371	125	438	3e-28	125
rs:WP_029506177	DNA topoisomerase III, partial [Lachnospiraceae bacterium AC2012].	29.97	357	217	9	61	396	250	594	3e-28	127
rs:WP_048084841	DNA topoisomerase I [Methanobacterium formicicum].	29.47	431	240	20	38	453	239	620	3e-28	128
rs:WP_046939034	hypothetical protein, partial [Xanthomonas euvesicatoria].	71.60	81	23	0	324	404	1	81	3e-28	117
rs:WP_031890592	DNA topoisomerase III, partial [Staphylococcus aureus].	26.90	342	230	6	57	396	174	497	3e-28	126
rs:WP_000779856	DNA topoisomerase III [Streptococcus pneumoniae].	30.77	364	225	11	37	397	225	564	3e-28	127
rs:WP_047192026	DNA topoisomerase [Microvirga vignae].	29.38	354	223	10	40	368	236	587	3e-28	128
rs:WP_021421870	DNA topoisomerase III [Peptoclostridium difficile].	29.87	375	235	10	27	397	214	564	3e-28	127
rs:WP_023409931	hypothetical protein [uncultured Thiohalocapsa sp. PB-PSB1].	30.40	329	205	8	99	407	6	330	3e-28	125
tr:D4LWP6_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.77	351	234	7	41	385	231	571	3e-28	128
rs:WP_026696403	hypothetical protein [Bacillus chagannorensis].	28.11	434	266	14	43	452	249	660	3e-28	128
rs:WP_040349721	DNA topoisomerase [Anaerococcus tetradius].	31.69	325	188	9	81	396	265	564	3e-28	127
rs:WP_021427439	DNA topoisomerase III [Peptoclostridium difficile].	29.87	375	235	10	27	397	214	564	3e-28	127
rs:WP_021320572	DNA topoisomerase [Streptococcus equi].	31.23	365	220	11	37	396	225	563	3e-28	127
tr:C2D5U5_LACBR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEI69841.1}; Flags: Fragment;	33.47	242	146	6	170	406	4	235	3e-28	123
rs:WP_041992809	DNA topoisomerase I, partial [Capnocytophaga cynodegmi].	30.82	292	186	8	59	347	259	537	3e-28	126
rs:WP_000779867	DNA topoisomerase III [Streptococcus agalactiae].	29.04	365	214	8	38	398	243	566	3e-28	127
rs:WP_012901076	DNA topoisomerase I [Methanocella paludicola].	27.03	407	250	13	56	453	253	621	3e-28	127
tr:C2CIB3_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.69	325	188	9	81	396	269	568	3e-28	127
rs:WP_022620845	DNA topoisomerase type IA Tn1549-like CTn5-Orf16 [Peptoclostridium difficile].	29.32	365	231	11	37	398	225	565	3e-28	126
rs:WP_007665430	DNA topoisomerase I [Bacteroides intestinalis].	28.11	370	246	10	60	427	262	613	3e-28	127
rs:WP_009529996	DNA topoisomerase III [Peptostreptococcaceae bacterium CM5].	31.69	366	221	12	37	398	227	567	3e-28	127
rs:YP_004289757	DNA topoisomerase i [Methanobacterium lacus].	28.27	428	248	17	39	453	245	626	3e-28	128
rs:WP_032463650	DNA topoisomerase III [Streptococcus pyogenes].	31.71	328	184	10	81	396	265	564	3e-28	127
rs:WP_006268556	DNA topoisomerase [Streptococcus constellatus].	31.40	363	222	10	37	396	225	563	3e-28	126
rs:WP_035109583	DNA topoisomerase [Finegoldia magna].	31.08	325	190	9	81	396	265	564	3e-28	126
rs:WP_023059450	DNA topoisomerase III [Peptoniphilus sp. BV3AC2].	31.08	325	190	9	81	396	265	564	4e-28	126
rs:WP_023078866	DNA topoisomerase III [Streptococcus pyogenes].	31.04	335	198	10	65	393	254	561	4e-28	126
tr:S9BCI7_STRAG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.14	365	228	11	37	398	262	602	4e-28	127
tr:D6SB76_FINMA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.08	325	190	9	81	396	269	568	4e-28	126
rs:WP_025194984	DNA topoisomerase III [Streptococcus agalactiae].	31.25	336	205	10	66	398	255	567	4e-28	126
rs:WP_021735919	DNA topoisomerase I [Coriobacteriaceae bacterium BV3Ac1].	27.73	440	254	13	38	459	293	686	4e-28	128
rs:WP_002841135	DNA topoisomerase III [Finegoldia magna].	30.56	324	197	8	81	398	265	566	4e-28	126
rs:WP_000779864	DNA topoisomerase III [Streptococcus agalactiae].	31.08	325	190	9	81	396	265	564	4e-28	126
rs:WP_005794014	DNA topoisomerase I [Bacteroides fragilis].	28.91	384	244	14	71	449	273	632	4e-28	127
rs:WP_012290743	MULTISPECIES: DNA topoisomerase III [Firmicutes].	31.08	325	190	9	81	396	265	564	4e-28	126
rs:WP_031789016	DNA topoisomerase III, partial [Staphylococcus aureus].	26.37	364	246	7	35	396	248	591	4e-28	127
rs:WP_040360493	DNA topoisomerase [Collinsella stercoris].	27.38	409	242	10	59	454	308	674	4e-28	128
rs:WP_005823252	DNA topoisomerase I [Bacteroides fragilis].	29.39	347	218	9	60	398	206	533	4e-28	127
rs:WP_009568422	DNA topoisomerase III family protein [Streptococcus intermedius].	30.85	363	224	11	37	396	225	563	4e-28	126
tr:B6G8D3_9ACTN	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.38	409	242	10	59	454	321	687	4e-28	128
rs:WP_044478705	DNA topoisomerase III, partial [Peptoclostridium difficile].	31.65	297	183	9	37	325	225	509	4e-28	125
rs:WP_021113548	DNA topoisomerase III family protein, partial [Haemophilus parasuis].	40.43	141	84	0	36	176	252	392	4e-28	124
rs:WP_017144917	DNA topoisomerase [Fusobacterium nucleatum].	25.24	424	287	9	40	448	236	644	4e-28	127
rs:WP_010008973	DNA topoisomerase III [Lactobacillus coryniformis].	25.97	385	242	8	61	445	252	593	4e-28	127
rs:WP_023039571	hypothetical protein [Fusobacterium nucleatum].	25.24	424	287	9	40	448	236	644	4e-28	127
rs:WP_004816326	DNA topoisomerase, partial [Anaerococcus hydrogenalis].	30.28	327	194	9	81	398	65	366	4e-28	124
tr:A0A0B3B3K1_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.81	429	261	14	38	453	185	573	4e-28	127
rs:WP_000779868	DNA topoisomerase III [Streptococcus agalactiae].	31.08	325	194	8	81	398	265	566	4e-28	126
rs:WP_038893010	DNA topoisomerase III, partial [Vibrio campbellii].	32.60	227	134	4	155	367	15	236	4e-28	121
rs:WP_006270428	DNA topoisomerase III [Streptococcus constellatus].	32.30	356	214	11	37	389	225	556	4e-28	126
rs:WP_038565766	DNA topoisomerase [Terribacillus aidingensis].	27.59	395	247	12	67	449	279	646	4e-28	127
rs:WP_012035171	DNA topoisomerase I [Methanocella arvoryzae].	28.12	409	243	14	56	453	253	621	4e-28	127
rs:WP_004612752	hypothetical protein [Tyzzerella nexilis].	29.28	345	228	7	47	385	237	571	5e-28	127
tr:A0A096CLF8_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGF46149.1}; Flags: Fragment;	28.66	328	212	8	101	426	3	310	5e-28	124
rs:WP_042702305	DNA topoisomerase I [Methanobrevibacter arboriphilus].	29.77	440	255	16	30	458	240	636	5e-28	127
tr:J8HJV3_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.14	334	229	6	35	365	239	564	5e-28	126
rs:WP_021326602	DNA topoisomerase III, partial [Photorhabdus temperata].	34.51	226	134	6	242	459	7	226	5e-28	122
rs:WP_021653369	DNA topoisomerase III [Clostridiales bacterium oral taxon 876].	29.75	316	196	7	48	355	262	559	5e-28	127
rs:WP_012901188	DNA topoisomerase I [Methanocella paludicola].	25.66	456	273	17	17	454	211	618	5e-28	127
rs:WP_040638921	DNA topoisomerase, partial [Microvirga lotononidis].	28.50	407	259	12	40	416	236	640	5e-28	127
rs:WP_004346359	DNA topoisomerase I [Prevotella buccae].	30.57	314	194	7	74	384	276	568	5e-28	127
tr:I4YSH0_9RHIZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.50	407	259	12	40	416	245	649	5e-28	127
rs:WP_037315920	DNA topoisomerase I [Salegentibacter sp. Hel_I_6].	28.23	333	228	5	48	379	250	572	5e-28	127
rs:WP_021661971	DNA topoisomerase [Porphyromonas gingivalis].	29.30	355	236	9	74	426	273	614	5e-28	127
rs:WP_028899761	DNA topoisomerase I [Prevotella sp. HJM029].	26.92	416	270	11	30	434	232	624	5e-28	127
tr:A0A075H2Q2_9EURY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.77	431	236	15	47	454	244	626	6e-28	127
rs:WP_048081003	MULTISPECIES: DNA topoisomerase I [Methanobacterium].	27.27	451	268	15	22	458	223	627	6e-28	127
tr:C0AQN2_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	41.29	155	89	2	36	190	251	403	6e-28	124
tr:W1YBX4_9ZZZZ	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ETJ39205.1}; Flags: Fragment;	42.11	133	76	1	39	171	1	132	6e-28	117
rs:WP_032536062	MULTISPECIES: DNA topoisomerase I [Bacteroides].	28.80	375	243	11	57	427	263	617	6e-28	127
rs:WP_023252897	DNA topoisomerase III, partial [Salmonella enterica].	35.75	179	109	1	207	385	6	178	6e-28	120
rs:WP_021824923	DNA topoisomerase [Prevotella salivae].	29.41	442	256	15	17	427	216	632	6e-28	127
rs:WP_029800604	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	40.14	147	88	0	258	404	1	147	6e-28	119
rs:WP_004835552	DNA topoisomerase III [Anaerococcus prevotii].	31.38	325	193	8	81	398	265	566	6e-28	125
rs:WP_039931121	hypothetical protein, partial [Anaerococcus lactolyticus].	30.36	336	204	11	67	396	257	568	6e-28	125
rs:WP_004377587	DNA topoisomerase I [Prevotella oris].	28.57	329	215	7	60	384	262	574	7e-28	127
tr:F3J5T5_PSEAP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	42.11	133	77	0	61	193	195	327	7e-28	123
rs:WP_046674940	DNA topoisomerase I [Sphingobacterium sp. Ag1].	26.58	395	268	11	46	428	247	631	7e-28	127
tr:W1ESZ2_ECOLX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CDL25211.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDL25211.1};	34.95	186	115	1	200	385	2	181	7e-28	120
rs:WP_031836252	DNA topoisomerase III, partial [Staphylococcus aureus].	26.37	364	246	7	35	396	248	591	7e-28	126
rs:WP_039421179	DNA topoisomerase I [Porphyromonas gulae].	28.84	371	247	10	18	377	217	581	7e-28	127
rs:WP_014262114	DNA topoisomerase III [Filifactor alocis].	31.21	330	193	9	75	397	264	566	8e-28	125
tr:H6NHR0_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	38.18	220	120	6	34	246	228	438	8e-28	126
rs:WP_033502019	DNA topoisomerase III, partial [Bifidobacterium kashiwanohense].	29.68	374	232	11	91	445	12	373	8e-28	124
rs:WP_007594042	DNA topoisomerase III [Lachnoanaerobaculum sp. OBRC5-5].	30.62	369	228	11	31	396	220	563	8e-28	125
rs:WP_029749639	DNA topoisomerase, partial [Streptococcus agalactiae].	31.73	312	187	10	90	398	2	290	8e-28	122
rs:WP_032854695	DNA topoisomerase I [Bacteroides ovatus].	29.68	283	185	6	70	350	272	542	8e-28	126
rs:WP_027374792	DNA topoisomerase I [Chryseobacterium sp. UNC8MFCol].	32.00	325	199	9	61	377	260	570	9e-28	126
rs:WP_009345214	DNA topoisomerase III [Peptoniphilus sp. oral taxon 836].	31.08	325	190	9	81	396	265	564	9e-28	125
rs:WP_032854693	MULTISPECIES: DNA topoisomerase I [Bacteroides].	29.68	283	185	6	70	350	272	542	9e-28	126
rs:WP_007851815	MULTISPECIES: DNA topoisomerase I [Bacteroides].	29.68	283	185	6	70	350	272	542	9e-28	126
tr:D4JQ77_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.81	359	219	13	56	396	284	627	9e-28	127
rs:WP_014030375	DNA topoisomerase I [Acidithiobacillus ferrivorans].	28.61	416	244	12	43	445	223	598	9e-28	126
rs:WP_041909636	hypothetical protein, partial [Candidatus Iainarchaeum andersonii].	26.07	445	278	16	22	454	222	627	9e-28	126
tr:T0ZGE6_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD27944.1}; Flags: Fragment;	41.88	160	86	3	219	377	1	154	9e-28	119
rs:WP_036739241	DNA topoisomerase [Peptoniphilus sp. BV3C26].	29.86	365	229	11	37	398	227	567	9e-28	125
rs:WP_042832025	DNA topoisomerase III, partial [Xanthomonas citri].	31.74	230	141	5	232	454	6	226	9e-28	120
rs:WP_034433748	DNA topoisomerase [Clostridiales bacterium S5-A14a].	29.86	365	229	11	37	398	227	567	9e-28	125
tr:U2JGA9_LACPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	35.29	238	127	9	102	330	1	220	9e-28	120
rs:WP_032842963	DNA topoisomerase I [Bacteroides ovatus].	29.68	283	185	6	70	350	272	542	1e-27	126
rs:WP_019034344	DNA topoisomerase III [Peptoniphilus lacrimalis].	30.98	326	189	9	81	396	265	564	1e-27	125
rs:WP_017645376	DNA topoisomerase III [Streptococcus agalactiae].	30.34	323	195	8	81	396	265	564	1e-27	125
rs:WP_005338472	hypothetical protein [Dorea formicigenerans].	28.99	345	229	7	47	385	237	571	1e-27	126
rs:WP_031878368	DNA topoisomerase III, partial [Staphylococcus aureus].	29.21	267	167	4	35	295	227	477	1e-27	124
rs:WP_036882351	hypothetical protein, partial [Prevotella nigrescens].	33.33	267	159	6	113	375	1	252	1e-27	123
rs:WP_005874605	DNA topoisomerase I [Porphyromonas gingivalis].	28.73	355	238	10	74	426	273	614	1e-27	126
rs:WP_039913594	DNA topoisomerase [Anaerococcus hydrogenalis].	29.59	338	205	9	65	396	254	564	1e-27	125
rs:WP_036978385	DNA topoisomerase III [Pseudobutyrivibrio sp. MD2005].	29.49	373	227	11	47	396	235	594	1e-27	125
rs:WP_041346435	topoisomerase I, partial [Oenococcus oeni].	32.24	245	149	6	160	397	17	251	1e-27	122
tr:U7UNB0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.86	365	229	11	37	398	251	591	1e-27	125
rs:WP_025341761	DNA topoisomerase III [Bifidobacterium breve].	28.64	391	248	11	74	445	267	645	1e-27	126
rs:WP_039121402	DNA topoisomerase [Fusobacterium necrophorum].	31.50	327	190	10	81	398	265	566	1e-27	125
tr:B6W693_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.59	338	205	9	65	396	258	568	1e-27	125
tr:C2BD67_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.36	336	204	11	67	396	261	572	1e-27	126
rs:WP_044567173	DNA topoisomerase [Anaerococcus sp. 9402080].	31.69	325	188	10	81	396	265	564	1e-27	125
rs:WP_004083178	DNA topoisomerase III [Clostridium sp. ASF502].	29.33	416	258	13	43	445	231	623	1e-27	126
rs:WP_019192519	DNA topoisomerase [Anaerococcus pacaensis].	30.21	341	199	10	65	396	254	564	1e-27	125
rs:WP_000779862	DNA topoisomerase III [Streptococcus pneumoniae].	30.18	338	203	9	65	396	254	564	1e-27	125
rs:WP_019124129	DNA topoisomerase [Peptoniphilus grossensis].	30.34	323	195	8	81	396	265	564	1e-27	125
rs:WP_022527651	toprim domain protein [Bifidobacterium longum].	28.50	407	237	13	74	450	267	649	1e-27	126
rs:WP_044137846	DNA topoisomerase I [Bacteroides oleiciplenus].	29.34	334	223	6	45	377	247	568	1e-27	126
rs:WP_008777083	DNA topoisomerase I [Bacteroides sp. 2_2_4].	29.08	392	254	11	37	424	238	609	1e-27	126
rs:WP_007754045	DNA topoisomerase I [Bacteroides finegoldii].	28.88	374	250	9	37	407	228	588	1e-27	125
tr:Q1AUL7_RUBXD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	29.92	381	215	14	86	454	288	628	1e-27	126
rs:WP_041329053	hypothetical protein, partial [Rubrobacter xylanophilus].	29.92	381	215	14	86	454	288	628	1e-27	125
rs:WP_019132809	DNA topoisomerase [Peptoniphilus obesi].	29.94	324	200	7	77	396	264	564	1e-27	125
tr:K9E6L5_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKU91481.1};	29.34	334	223	6	45	377	248	569	1e-27	125
rs:WP_002981562	DNA topoisomerase [Chryseobacterium gleum].	29.10	354	200	9	47	384	259	577	1e-27	125
rs:WP_036889351	DNA topoisomerase I [Porphyromonas crevioricanis].	27.73	422	282	12	18	428	217	626	1e-27	125
rs:WP_048327782	DNA topoisomerase [Streptococcus dysgalactiae].	30.77	364	225	11	37	397	225	564	1e-27	124
rs:WP_020208865	hypothetical protein [Gilvimarinus chinensis].	25.45	440	269	13	35	459	207	602	1e-27	125
rs:WP_003679507	DNA topoisomerase III [Lactobacillus coryniformis].	25.97	385	242	8	61	445	252	593	1e-27	125
rs:WP_007486318	DNA topoisomerase I [Bacteroides nordii].	29.33	283	186	6	70	350	272	542	1e-27	125
rs:WP_033609470	topoisomerase I, partial [Lactobacillus plantarum].	34.55	220	125	6	163	374	5	213	1e-27	119
rs:WP_041160385	DNA topoisomerase [Peptoclostridium difficile].	30.03	323	196	8	81	396	265	564	2e-27	125
rs:WP_002686858	DNA topoisomerase III [Treponema denticola].	30.00	310	192	7	56	357	257	549	2e-27	125
rs:WP_016462896	DNA topoisomerase III [Bifidobacterium breve].	28.64	391	248	11	74	445	267	645	2e-27	125
rs:WP_034255044	DNA topoisomerase III [Bifidobacterium kashiwanohense].	29.16	391	246	11	74	445	267	645	2e-27	125
rs:WP_005819871	DNA topoisomerase I [Bacteroides fragilis].	26.56	369	251	9	61	427	263	613	2e-27	125
tr:A0A091C1Y9_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.77	192	131	0	43	234	203	394	2e-27	123
rs:WP_036350533	DNA topoisomerase, partial [Microvirga sp. BSC39].	29.01	355	224	11	40	368	236	588	2e-27	125
rs:WP_033609624	topoisomerase I, partial [Lactobacillus plantarum].	34.70	219	126	6	163	374	5	213	2e-27	119
rs:WP_005776763	DNA topoisomerase I [Bacteroides fragilis].	28.73	369	242	8	59	424	259	609	2e-27	125
rs:WP_008566167	DNA topoisomerase I [Prevotella maculosa].	29.20	363	222	12	74	425	276	614	2e-27	125
rs:WP_047638995	DNA topoisomerase, partial [Enterococcus faecium].	31.82	264	161	6	180	433	1	255	2e-27	120
rs:WP_012797160	DNA topoisomerase III [Anaerococcus prevotii].	30.89	327	192	9	81	398	265	566	2e-27	124
rs:WP_021002848	DNA topoisomerase [Streptococcus intermedius].	31.70	347	210	11	37	380	225	547	2e-27	124
rs:WP_023055012	DNA topoisomerase III [Peptoniphilus sp. BV3C26].	30.12	342	198	10	65	396	254	564	2e-27	124
tr:F8K7Y7_STRPY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.40	328	185	10	81	396	269	568	2e-27	124
rs:WP_002843661	DNA topoisomerase III [Peptostreptococcus anaerobius].	31.13	363	223	10	37	396	225	563	2e-27	124
rs:WP_029729038	DNA topoisomerase I [Elizabethkingia anophelis].	29.41	323	209	8	74	391	277	585	2e-27	125
tr:A0A0A1GXE3_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.27	251	137	7	56	294	10	239	2e-27	120
rs:WP_005805798	DNA topoisomerase I [Bacteroides fragilis].	28.53	375	244	11	57	427	263	617	2e-27	125
rs:WP_043945779	DNA topoisomerase III, partial [Carnobacterium sp. WN1359].	29.39	296	182	9	171	454	1	281	2e-27	121
rs:WP_019138735	DNA topoisomerase [Peptoniphilus timonensis].	30.28	327	194	9	81	398	265	566	2e-27	124
rs:WP_008766575	DNA topoisomerase I [Bacteroides sp. 1_1_6].	28.46	376	235	10	60	427	206	555	2e-27	125
rs:WP_032846518	MULTISPECIES: DNA topoisomerase I [Bacteroides].	29.08	392	254	10	37	424	238	609	2e-27	125
rs:WP_028071503	DNA topoisomerase I [Sphingobacterium thalpophilum].	26.58	395	268	11	46	428	247	631	2e-27	125
rs:WP_002333469	hypothetical protein, partial [Enterococcus faecium].	31.68	262	155	7	198	449	1	248	2e-27	120
rs:WP_036679138	DNA topoisomerase I [Pedobacter oryzae].	28.62	325	217	9	59	380	267	579	2e-27	124
rs:WP_039848609	DNA topoisomerase I [Parabacteroides sp. D13].	28.95	380	237	11	55	427	202	555	2e-27	125
rs:WP_000779861	DNA topoisomerase III [Streptococcus agalactiae].	30.46	325	192	9	81	396	265	564	2e-27	124
rs:WP_016295879	DNA topoisomerase III [Lachnospiraceae bacterium M18-1].	31.41	347	216	10	49	385	237	571	2e-27	125
rs:WP_020999844	DNA topoisomerase III [Streptococcus anginosus].	31.46	356	217	11	37	389	225	556	2e-27	124
gp:HF952106_658	DNA topoisomerase III [Streptococcus agalactiae ILRI112]	30.34	323	195	8	81	396	265	564	2e-27	124
tr:C7X7R3_9PORP	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	28.95	380	237	11	55	427	220	573	2e-27	125
rs:WP_044102072	DNA topoisomerase III, partial [Xanthomonas citri].	39.13	161	91	2	36	192	241	398	3e-27	122
rs:WP_034579773	DNA topoisomerase [Kallipyga massiliensis].	29.75	363	228	11	37	396	227	565	3e-27	124
tr:U3N979_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.10	254	167	4	37	286	225	474	3e-27	123
rs:WP_012952161	DNA topoisomerase III [Listeria monocytogenes].	27.30	392	250	12	59	433	271	644	3e-27	125
rs:WP_009347193	DNA topoisomerase I [Alloprevotella rava].	27.86	402	269	11	35	427	236	625	3e-27	125
tr:U5SEA8_9LACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AGY82458.1};	29.29	297	183	9	170	454	26	307	3e-27	121
rs:WP_028728974	DNA topoisomerase I, partial [Parabacteroides gordonii].	31.87	273	172	7	59	328	127	388	3e-27	122
rs:WP_000779865	DNA topoisomerase III [Streptococcus agalactiae].	30.46	325	192	9	81	396	265	564	3e-27	124
rs:WP_032684902	DNA topoisomerase III [Bifidobacterium longum].	28.75	407	236	12	74	450	267	649	3e-27	125
rs:WP_015419613	MULTISPECIES: DNA topoisomerase III [Hydrogenobaculum].	26.26	358	216	7	55	385	288	624	3e-27	125
rs:WP_025434822	DNA topoisomerase [Eubacterium acidaminophilum].	29.86	365	228	11	37	396	225	566	3e-27	124
rs:WP_002678088	DNA topoisomerase [Capnocytophaga sputigena].	27.64	398	254	15	66	446	264	644	3e-27	125
rs:WP_047212299	DNA topoisomerase [Streptococcus agalactiae].	29.75	363	228	11	37	396	227	565	3e-27	124
rs:WP_017644362	DNA topoisomerase III [Streptococcus agalactiae].	30.77	325	191	9	81	396	265	564	3e-27	124
rs:WP_019117236	DNA topoisomerase III [Anaerococcus sp. PH9].	30.89	327	192	9	81	398	265	566	3e-27	124
rs:WP_007057140	DNA topoisomerase III [Bifidobacterium longum].	29.04	396	249	12	74	450	267	649	3e-27	124
rs:WP_017646113	MULTISPECIES: DNA topoisomerase III [Streptococcus].	31.32	364	223	11	37	397	225	564	4e-27	124
rs:WP_007391818	MULTISPECIES: DNA topoisomerase [Firmicutes].	29.75	363	228	11	37	396	227	565	4e-27	123
rs:WP_036850011	DNA topoisomerase I [Porphyromonas cangingivalis].	27.32	421	283	12	18	427	217	625	4e-27	124
rs:WP_012961161	DNA topoisomerase III [Bacillus pseudofirmus].	28.30	371	234	12	86	446	3	351	4e-27	122
rs:WP_011108225	DNA topoisomerase III [Bacteroides thetaiotaomicron].	28.38	377	256	7	37	411	238	602	4e-27	124
rs:WP_026503225	DNA topoisomerase III [Bifidobacterium boum].	28.90	353	219	11	51	377	242	588	4e-27	124
rs:WP_047379720	DNA topoisomerase III [Bifidobacterium longum].	28.75	407	236	12	74	450	267	649	4e-27	124
rs:WP_041080612	DNA topoisomerase III [Bifidobacterium longum].	28.75	407	236	12	74	450	267	649	4e-27	124
rs:WP_000779863	DNA topoisomerase III [Streptococcus agalactiae].	30.58	327	193	9	81	398	265	566	4e-27	123
rs:WP_009381486	DNA topoisomerase III [Megasphaera genomosp. type_1].	29.59	365	230	11	37	398	227	567	4e-27	123
rs:WP_021672576	DNA topoisomerase [Prevotella sp. F0091].	27.08	421	284	11	18	427	217	625	4e-27	124
rs:WP_042230926	DNA topoisomerase [Peptoniphilus senegalensis].	30.30	363	226	11	37	396	227	565	4e-27	123
rs:WP_032735465	DNA topoisomerase III [Bifidobacterium longum].	28.75	407	236	12	74	450	267	649	4e-27	124
rs:WP_008783291	DNA topoisomerase III [Bifidobacterium sp. 12_1_47BFAA].	28.75	407	236	12	74	450	267	649	4e-27	124
rs:WP_037443261	DNA topoisomerase I [Sphingobacterium antarcticum].	28.02	339	227	10	69	402	277	603	4e-27	124
rs:WP_019879542	hypothetical protein [Succinispira mobilis].	27.99	418	257	13	50	452	264	652	4e-27	124
tr:W4RXJ6_9XANT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	35.62	160	102	1	32	190	193	352	4e-27	120
rs:WP_032459429	DNA topoisomerase [Streptococcus agalactiae].	29.75	363	228	11	37	396	227	565	4e-27	123
rs:WP_021975616	topoisomerase IA [Bifidobacterium longum CAG:69].	28.75	407	236	12	74	450	267	649	4e-27	124
rs:WP_016648539	DNA topoisomerase III [Facklamia hominis].	30.46	325	192	9	81	396	265	564	4e-27	123
rs:WP_013037299	DNA topoisomerase [Methanohalophilus mahii].	27.05	440	267	14	34	454	238	642	4e-27	124
rs:WP_010080729	DNA topoisomerase III [Bifidobacterium longum].	28.75	407	236	12	74	450	267	649	5e-27	124
tr:W0WM01_PSEAI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CDH72766.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDH72766.1};	36.57	175	102	3	280	454	2	167	5e-27	117
rs:WP_007135634	DNA topoisomerase I [Prevotella salivae].	28.57	364	225	9	74	425	276	616	5e-27	124
rs:WP_048185804	DNA topoisomerase I [Methanoculleus sp. S3Fa].	25.89	448	272	16	18	450	216	618	5e-27	125
rs:WP_015512177	Topoisomerase IA [Bifidobacterium longum].	28.75	407	236	12	74	450	267	649	5e-27	124
gpu:CP009928_113	DNA topoisomerase I [Chryseobacterium gallinarum]	28.48	330	205	7	74	392	276	585	5e-27	124
tr:U2E4L1_9BACE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERI89122.1};	29.30	355	236	10	74	426	25	366	5e-27	122
rs:WP_004026788	DNA topoisomerase III [Ureaplasma urealyticum].	30.58	327	193	9	81	398	265	566	5e-27	123
rs:WP_003034176	DNA topoisomerase III [Streptococcus anginosus].	32.02	356	215	11	37	389	225	556	5e-27	123
rs:WP_038654227	DNA topoisomerase I [Mucinivorans hirudinis].	29.65	371	242	9	24	391	225	579	5e-27	124
rs:WP_011498278	DNA topoisomerase I [Methanococcoides burtonii].	25.98	458	281	17	11	454	214	627	5e-27	124
rs:WP_025271599	DNA topoisomerase [Streptococcus anginosus].	31.46	356	217	11	37	389	225	556	5e-27	123
rs:WP_012803306	DNA topoisomerase [Cryptobacterium curtum].	27.27	407	253	11	60	459	307	677	5e-27	124
rs:WP_002838480	DNA topoisomerase III [Finegoldia magna].	30.91	330	188	10	81	398	265	566	5e-27	123
tr:U7UHG3_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.75	363	228	11	37	396	251	589	5e-27	123
rs:WP_004584311	DNA topoisomerase [Porphyromonas gingivalis].	27.32	421	283	12	18	427	217	625	5e-27	124
rs:WP_007052706	DNA topoisomerase III [Bifidobacterium longum].	28.75	407	236	12	74	450	267	649	5e-27	124
rs:WP_036889711	DNA topoisomerase I [Porphyromonas crevioricanis].	26.28	411	273	12	22	426	221	607	5e-27	124
rs:WP_036757769	DNA topoisomerase [Peptoniphilus lacrimalis].	30.77	325	191	9	81	396	265	564	5e-27	123
tr:W1U0R1_STRAP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.75	363	228	11	37	396	262	600	6e-27	123
rs:WP_005956335	DNA topoisomerase III [Peptoniphilus harei].	30.46	325	192	9	81	396	265	564	6e-27	123
rs:WP_017143085	DNA topoisomerase I [Bacteroides finegoldii].	30.61	330	211	9	60	384	141	457	6e-27	123
rs:WP_041239714	DNA topoisomerase [Gordonibacter pamelaeae].	27.74	465	289	14	6	459	249	677	6e-27	124
tr:K5DE93_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKJ91283.1};	30.61	330	211	9	60	384	138	454	6e-27	123
rs:WP_036845243	DNA topoisomerase I, partial [Porphyromonas sp. COT-108 OH1349].	28.57	371	248	10	18	377	250	614	6e-27	123
rs:WP_042991347	DNA topoisomerase III, partial [Bifidobacterium adolescentis].	31.78	387	214	15	47	397	172	544	7e-27	124
rs:WP_016309110	DNA topoisomerase I [Enterorhabdus caecimuris].	27.80	410	245	13	61	459	318	687	7e-27	124
rs:WP_022082367	DNA topoisomerase III [Bacteroides sp. CAG:144].	34.13	208	131	5	186	392	2	204	7e-27	119
rs:WP_004346383	DNA topoisomerase I [Prevotella buccae].	28.57	406	260	10	45	443	246	628	7e-27	124
rs:WP_016622814	DNA topoisomerase, partial [Enterococcus faecalis].	31.99	272	173	5	57	325	268	530	7e-27	122
rs:WP_032737758	DNA topoisomerase III [Bifidobacterium longum].	28.11	402	236	12	74	445	267	645	7e-27	124
rs:WP_004362423	DNA topoisomerase III [Prevotella nigrescens].	27.32	421	283	12	18	427	217	625	7e-27	124
rs:WP_042664917	hypothetical protein [Thaumarchaeota archaeon SCGC AB-179-E04].	28.77	424	251	15	45	454	254	640	7e-27	124
rs:WP_028962263	DNA topoisomerase I [Sulfobacillus thermosulfidooxidans].	24.74	473	273	14	33	449	212	657	7e-27	124
rs:WP_033493981	DNA topoisomerase III [Bifidobacterium thermophilum].	28.60	437	265	16	40	445	232	652	7e-27	124
rs:WP_007054353	DNA topoisomerase III [Bifidobacterium longum].	28.75	407	236	12	74	450	267	649	7e-27	124
tr:A0A075G5E7_9EURY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.87	335	220	8	65	387	279	600	7e-27	124
rs:WP_021665030	DNA topoisomerase [Porphyromonas gingivalis].	28.73	355	238	10	74	426	273	614	7e-27	124
rs:WP_004818409	DNA topoisomerase, partial [Anaerococcus hydrogenalis].	30.28	327	194	9	81	398	65	366	7e-27	120
tr:A0A0B8QFV7_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	40.29	139	83	0	32	170	249	387	7e-27	121
rs:WP_026487967	DNA topoisomerase III [Butyrivibrio sp. XBB1001].	29.06	382	228	11	60	400	305	684	7e-27	124
rs:WP_015052783	DNA topoisomerase I [Methanolobus psychrophilus].	25.64	429	267	13	40	458	243	629	7e-27	124
rs:WP_036651035	DNA topoisomerase I [Parabacteroides distasonis].	29.05	358	232	9	71	424	273	612	7e-27	124
rs:WP_007056103	DNA topoisomerase III [Bifidobacterium longum].	28.64	391	248	11	74	445	267	645	8e-27	124
rs:WP_027432286	hypothetical protein [Lachnospira multipara].	26.76	441	277	17	30	450	200	614	8e-27	124
rs:WP_011843614	DNA topoisomerase I [Methanoculleus marisnigri].	25.67	448	273	16	18	450	216	618	8e-27	124
rs:WP_036617832	DNA topoisomerase I [Parabacteroides distasonis].	29.05	358	232	9	71	424	273	612	8e-27	123
rs:WP_034849209	DNA topoisomerase, partial [Clostridium hydrogeniformans].	28.80	368	226	11	47	398	259	606	8e-27	123
rs:WP_018579558	MULTISPECIES: DNA topoisomerase III [Firmicutes].	30.06	326	196	9	79	397	263	563	8e-27	122
rs:WP_005680137	MULTISPECIES: DNA topoisomerase I [Bacteroides].	31.02	332	207	11	60	384	199	515	8e-27	123
rs:WP_038352446	hypothetical protein, partial [Eubacterium limosum].	27.10	417	262	15	50	446	258	652	8e-27	123
rs:WP_032856232	DNA topoisomerase I [Bacteroides ovatus].	31.02	332	207	11	60	384	199	515	8e-27	123
rs:WP_038426447	DNA topoisomerase III [Bifidobacterium longum].	28.75	407	236	12	74	450	267	649	9e-27	123
rs:WP_002839237	DNA topoisomerase, partial [Finegoldia magna].	30.56	324	197	8	81	398	24	325	9e-27	119
tr:C3QRJ0_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.02	332	207	11	60	384	216	532	9e-27	123
rs:WP_042811193	DNA topoisomerase III, partial [Xanthomonas citri].	33.01	206	129	4	249	454	1	197	9e-27	117
rs:WP_008451377	DNA topoisomerase, partial [Prevotella amnii].	27.89	380	223	10	74	425	230	586	1e-26	123
rs:WP_000779858	DNA topoisomerase III [Streptococcus agalactiae].	31.28	358	219	11	43	397	231	564	1e-26	122
tr:K8EI91_CARML	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.04	307	189	4	86	390	5	278	1e-26	120
tr:D4WMC6_BACOV	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.02	332	207	11	60	384	216	532	1e-26	123
rs:WP_031859989	DNA topoisomerase III, partial [Staphylococcus aureus].	26.38	345	226	10	115	454	1	322	1e-26	119
rs:WP_031806813	DNA topoisomerase III, partial [Staphylococcus aureus].	30.30	264	163	7	189	450	1	245	1e-26	119
rs:WP_016121776	DNA topoisomerase 3, partial [Bacillus cereus].	35.45	189	116	3	216	401	1	186	1e-26	119
rs:WP_033500972	DNA topoisomerase III, partial [Bifidobacterium kashiwanohense].	32.28	347	191	12	91	405	12	346	1e-26	121
rs:WP_032738539	DNA topoisomerase III [Bifidobacterium longum].	28.36	402	235	11	74	445	267	645	1e-26	123
rs:WP_032530912	DNA topoisomerase I [Bacteroides fragilis].	28.13	391	259	8	37	424	238	609	1e-26	123
rs:WP_005805519	DNA topoisomerase I [Bacteroides fragilis].	28.15	373	230	11	59	427	259	597	1e-26	123
tr:D0TV73_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	31.02	332	207	11	60	384	221	537	1e-26	123
rs:WP_045152427	DNA topoisomerase III, partial [Escherichia coli].	41.42	169	93	3	27	193	239	403	1e-26	120
rs:WP_022740226	DNA topoisomerase [Adlercreutzia equolifaciens].	27.94	408	247	14	61	459	318	687	1e-26	123
rs:WP_013194217	DNA topoisomerase [Methanohalobium evestigatum].	27.74	447	263	16	31	454	235	644	1e-26	123
rs:WP_012025057	DNA topoisomerase [Flavobacterium johnsoniae].	30.34	323	205	9	74	391	277	584	1e-26	123
rs:WP_032820860	topoisomerase I, partial [Oenococcus oeni].	33.20	256	144	9	56	302	1	238	1e-26	117
rs:WP_032585411	DNA topoisomerase I [Bacteroides fragilis].	27.88	373	255	6	37	407	238	598	1e-26	123
tr:G1V000_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	35.16	182	114	3	93	274	2	179	1e-26	115
rs:WP_002352642	DNA topoisomerase, partial [Enterococcus faecium].	33.80	213	129	4	156	365	38	241	1e-26	118
rs:WP_013683176	DNA topoisomerase I [Archaeoglobus veneficus].	26.67	405	251	13	56	454	253	617	1e-26	122
rs:WP_048094511	DNA topoisomerase I [Geoglobus ahangari].	27.27	407	242	14	56	454	252	612	1e-26	122
tr:L8JM96_9BACT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ELR68512.1};	32.41	216	137	5	101	313	2	211	1e-26	116
rs:WP_007485367	MULTISPECIES: DNA topoisomerase I [Bacteroides].	28.38	377	256	7	37	411	238	602	1e-26	122
rs:WP_018261492	DNA topoisomerase [Methylobacterium sp. WSM2598].	27.64	416	239	11	56	413	252	663	1e-26	123
rs:WP_025067452	DNA topoisomerase I [Prevotella denticola].	26.68	416	271	11	30	434	232	624	1e-26	122
rs:WP_014709363	DNA topoisomerase I [Prevotella intermedia].	26.84	421	285	11	18	427	217	625	2e-26	122
rs:WP_009419771	DNA topoisomerase [Capnocytophaga sp. oral taxon 380].	27.39	398	255	15	66	446	264	644	2e-26	122
rs:WP_023152731	DNA topoisomerase [Eubacterium brachy].	30.38	339	198	13	64	385	300	617	2e-26	122
rs:WP_002337938	DNA topoisomerase III [Enterococcus faecium].	28.14	334	210	7	68	397	281	588	2e-26	123
rs:WP_017706951	hypothetical protein, partial [Pseudomonas syringae].	36.31	179	112	1	228	406	2	178	2e-26	116
rs:WP_000779866	DNA topoisomerase III [Streptococcus agalactiae].	28.34	367	214	9	38	398	243	566	2e-26	122
rs:WP_016478637	DNA topoisomerase III [Capnocytophaga sp. oral taxon 336].	26.62	417	269	15	45	446	250	644	2e-26	122
rs:WP_035023093	DNA topoisomerase I [Carnobacterium sp. WN1374].	27.10	428	251	16	50	457	228	614	2e-26	122
rs:WP_047199200	DNA topoisomerase [Streptococcus agalactiae].	29.75	363	228	12	37	396	227	565	2e-26	122
rs:WP_032600052	DNA topoisomerase I [Bacteroides fragilis].	28.38	377	256	7	37	411	238	602	2e-26	122
rs:WP_024905748	hypothetical protein [Burkholderia andropogonis].	34.18	275	159	10	189	446	3	272	2e-26	119
rs:WP_012333944	DNA topoisomerase [Methylobacterium sp. 4-46].	27.64	416	239	11	56	413	252	663	2e-26	122
rs:WP_041690182	hypothetical protein, partial [Eubacterium limosum].	27.10	417	262	15	50	446	258	652	2e-26	122
rs:WP_044190226	DNA topoisomerase I [Porphyromonas sp. COT-290 OH860].	27.32	421	283	12	18	427	217	625	2e-26	122
rs:WP_004366614	DNA topoisomerase I [Prevotella nigrescens].	26.84	421	285	11	18	427	217	625	2e-26	122
rs:WP_028027328	DNA topoisomerase [Enterorhabdus mucosicola].	27.80	410	245	13	61	459	318	687	2e-26	122
rs:WP_009640589	DNA topoisomerase [Capnocytophaga sp. CM59].	26.62	402	271	9	60	450	262	650	2e-26	122
rs:WP_016662014	DNA topoisomerase III [Bacteroides stercoris].	28.57	392	256	10	37	424	238	609	2e-26	122
rs:WP_008688070	DNA topoisomerase III [Eubacterium sp. 3_1_31].	27.73	357	238	7	47	398	235	576	2e-26	122
rs:WP_008783346	DNA topoisomerase III [Bifidobacterium sp. 12_1_47BFAA].	31.00	371	216	11	40	377	233	596	2e-26	122
rs:WP_033624355	DNA topoisomerase, partial [Enterococcus faecium].	28.14	334	210	7	68	397	281	588	2e-26	122
rs:WP_032542359	DNA topoisomerase I [Bacteroides fragilis].	26.29	369	252	9	61	427	263	613	2e-26	122
rs:WP_014298777	DNA topoisomerase I [Bacteroides fragilis].	27.88	391	260	8	37	424	238	609	2e-26	122
rs:WP_003813716	DNA topoisomerase III [Bifidobacterium bifidum].	31.10	373	217	11	40	379	233	598	2e-26	122
rs:WP_011068071	DNA topoisomerase III [Bifidobacterium longum].	28.75	407	236	12	74	450	426	808	2e-26	122
rs:WP_020327389	DNA topoisomerase III, partial [Pseudomonas syringae].	37.20	207	116	4	236	440	3	197	2e-26	115
rs:WP_039972488	DNA topoisomerase I [Bacteroides pyogenes].	29.30	355	236	10	74	426	273	614	3e-26	122
rs:WP_047284460	DNA topoisomerase III [Bifidobacterium bifidum].	30.87	366	213	11	47	379	240	598	3e-26	122
rs:WP_033596185	DNA topoisomerase III, partial [Enterococcus faecalis].	34.66	176	115	0	47	222	243	418	3e-26	119
tr:A0A068Z373_BIFBI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.42	366	211	11	47	379	240	598	3e-26	122
tr:M1ZR26_CLOBO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	36.99	173	98	2	46	212	3	170	3e-26	114
rs:WP_002311832	DNA topoisomerase [Enterococcus faecium].	28.14	334	210	7	68	397	281	588	3e-26	122
tr:F2NLP3_MARHT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.91	412	223	14	61	454	248	603	3e-26	122
rs:WP_047298255	DNA topoisomerase III [Bifidobacterium bifidum].	31.15	366	212	11	47	379	240	598	3e-26	122
rs:WP_004318624	DNA topoisomerase I [Bacteroides ovatus].	30.72	332	208	11	60	384	199	515	3e-26	121
rs:WP_005800238	DNA topoisomerase I [Bacteroides fragilis].	27.88	391	260	8	37	424	238	609	3e-26	122
tr:E3GMG1_EUBLK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.20	397	257	13	50	433	258	635	3e-26	122
rs:WP_013671538	DNA topoisomerase I [Prevotella denticola].	30.57	314	200	8	74	384	276	574	3e-26	122
rs:WP_019177234	hypothetical protein [Methanomassiliicoccus luminyensis].	27.17	449	268	16	23	454	218	624	3e-26	122
tr:V8CKV1_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.37	383	250	9	61	434	236	595	3e-26	122
tr:G9QZP6_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHM92695.1};	32.32	198	123	2	180	375	3	191	3e-26	114
rs:WP_036885046	hypothetical protein, partial [Prevotella disiens].	29.25	318	199	8	113	426	1	296	3e-26	119
rs:WP_038892912	DNA topoisomerase III, partial [Vibrio campbellii].	31.28	227	137	4	155	367	15	236	3e-26	116
rs:WP_041658130	DNA topoisomerase I, partial [Marinithermus hydrothermalis].	27.91	412	223	14	61	454	248	603	3e-26	122
rs:WP_002418952	DNA topoisomerase, partial [Enterococcus faecalis].	33.06	245	152	4	157	396	25	262	3e-26	118
rs:WP_027866354	hypothetical protein [Massilia alkalitolerans].	33.06	248	152	6	30	271	259	498	3e-26	120
rs:WP_036874401	DNA topoisomerase I, partial [Prevotella nigrescens].	26.37	383	250	9	61	434	237	596	3e-26	121
rs:WP_010776949	DNA topoisomerase III [Enterococcus faecium].	28.14	334	210	7	68	397	281	588	3e-26	122
rs:WP_010726672	hypothetical protein, partial [Enterococcus faecium].	28.14	334	210	7	68	397	160	467	3e-26	121
rs:WP_036889231	hypothetical protein, partial [Prevotella aurantiaca].	29.65	317	197	8	113	425	1	295	3e-26	118
rs:WP_021069091	transposase [Sphingobacterium paucimobilis].	26.78	366	240	10	46	398	247	597	4e-26	121
tr:H0AA89_HALSG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.37	475	284	18	2	454	202	637	4e-26	121
rs:WP_004374762	DNA topoisomerase I [Prevotella oris].	30.57	314	200	8	74	384	276	574	4e-26	121
rs:WP_021974605	DNA topoisomerase [Firmicutes bacterium CAG:884].	25.74	470	279	15	1	450	172	591	4e-26	121
rs:WP_035218062	DNA topoisomerase I, partial [Acidithiobacillus thiooxidans].	29.45	421	252	13	32	445	215	597	4e-26	121
tr:Q33E26_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.14	334	210	7	68	397	281	588	4e-26	122
rs:WP_014760411	DNA topoisomerase III [Bifidobacterium bifidum].	30.83	373	218	11	40	379	233	598	4e-26	121
rs:WP_009411156	DNA topoisomerase [Capnocytophaga sp. oral taxon 324].	28.25	400	251	15	66	446	263	645	4e-26	121
rs:WP_009278772	DNA topoisomerase [Olsenella sp. oral taxon 809].	27.55	432	251	13	40	454	293	679	4e-26	122
tr:F4BRM5_CARS1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	27.00	426	254	14	50	457	73	459	4e-26	120
rs:WP_036889132	DNA topoisomerase I, partial [Prevotella enoeca].	31.94	263	156	6	74	334	73	314	4e-26	117
tr:A5ZUI2_9FIRM	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:EDM86762.1};	29.81	265	165	7	155	399	20	283	4e-26	117
rs:WP_020374729	hypothetical protein [Sulfobacillus thermosulfidooxidans].	24.52	473	274	14	33	449	212	657	4e-26	121
rs:WP_021151602	DNA topoisomerase III [Streptococcus sp. HSISS3].	27.86	341	221	9	59	385	110	439	4e-26	120
rs:WP_013898006	DNA topoisomerase I [Methanosalsum zhilinae].	27.25	433	255	15	37	454	239	626	4e-26	121
rs:WP_047270549	DNA topoisomerase III [Bifidobacterium bifidum].	30.83	373	218	11	40	379	233	598	4e-26	121
rs:WP_048103338	DNA topoisomerase I, partial [Methanosarcina barkeri].	26.80	403	237	15	66	454	271	629	4e-26	121
tr:D3AV32_9CLOT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EFC94324.1}; Flags: Fragment;	33.20	244	143	6	164	396	1	235	4e-26	116
rs:WP_042225960	DNA topoisomerase I, partial [Porphyromonas crevioricanis].	26.37	402	275	10	35	427	20	409	5e-26	119
rs:WP_034440685	DNA topoisomerase [Clostridiales bacterium S5-A11].	30.49	328	188	10	81	396	265	564	5e-26	120
rs:WP_011246962	DNA topoisomerase [Bacillus clausii].	27.23	382	242	12	58	424	264	624	5e-26	121
rs:WP_013329862	DNA topoisomerase I [Methanolacinia petrolearia].	25.92	436	269	15	25	449	226	618	5e-26	122
tr:A0A073IAB4_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KEJ86500.1};	28.57	392	256	10	37	424	238	609	5e-26	121
rs:WP_047299168	DNA topoisomerase III [Bifidobacterium bifidum].	30.83	373	218	11	40	379	233	598	5e-26	121
rs:WP_026648908	DNA topoisomerase III [Blautia wexlerae].	28.04	378	238	11	79	445	264	618	5e-26	121
rs:WP_039993093	DNA topoisomerase [Slackia sp. CM382].	27.78	432	266	14	37	459	284	678	5e-26	121
rs:WP_018300335	hypothetical protein [Fangia hongkongensis].	30.20	457	241	23	28	452	212	622	5e-26	121
rs:WP_004038803	DNA topoisomerase I [Methanofollis liminatans].	24.89	446	278	15	18	449	216	618	5e-26	122
rs:WP_010894311	hypothetical protein, partial [Xylella fastidiosa].	63.41	82	30	0	29	110	35	116	5e-26	113
tr:J6IWI6_9ACTN	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.78	432	266	14	37	459	282	676	5e-26	121
rs:WP_025072617	DNA topoisomerase I [Prevotella timonensis].	29.01	355	229	8	74	426	276	609	5e-26	121
rs:WP_028494122	DNA topoisomerase I [Thermus antranikianii].	27.29	447	250	15	36	454	218	617	5e-26	121
rs:WP_018920050	DNA topoisomerase I [Prevotella oris].	27.36	402	271	11	35	427	236	625	5e-26	121
tr:T4BJJ7_PEPDI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.17	427	269	12	40	459	286	677	5e-26	121
rs:WP_032819641	topoisomerase I, partial [Oenococcus oeni].	33.22	283	158	11	33	302	46	310	5e-26	117
rs:WP_039086265	conjugal transfer protein TraE, partial [Gallibacterium anatis].	33.84	198	125	2	10	207	226	417	5e-26	118
tr:F9Y0V9_BIFBU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.11	461	284	13	17	445	128	568	6e-26	120
rs:WP_002887270	topoisomerase IA [Streptococcus salivarius].	27.57	341	222	8	59	385	293	622	6e-26	121
rs:WP_011307376	DNA topoisomerase I [Methanosarcina barkeri].	26.80	403	237	15	66	454	271	629	6e-26	121
rs:WP_006447066	DNA topoisomerase I [Alicyclobacillus hesperidum].	27.29	425	255	11	50	457	227	614	6e-26	121
rs:WP_017168920	hypothetical protein, partial [Xanthomonas axonopodis].	52.63	114	54	0	30	143	237	350	6e-26	117
rs:WP_036868224	DNA topoisomerase I [Porphyromonas canoris].	28.03	371	250	9	18	377	217	581	6e-26	120
tr:T0U6H2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.67	300	188	9	41	328	455	746	6e-26	121
rs:WP_006363114	DNA topoisomerase [Slackia exigua].	27.55	432	267	14	37	459	284	678	6e-26	121
rs:WP_022319904	DNA topoisomerase [Clostridium sp. CAG:349].	27.52	436	252	15	47	454	229	628	6e-26	120
rs:WP_014485593	DNA topoisomerase III [Bifidobacterium longum].	28.36	402	235	11	74	445	267	645	7e-26	120
rs:WP_013905219	endonuclease [Pyrococcus yayanosii].	29.27	369	201	12	112	457	783	1114	7e-26	121
rs:WP_008336478	DNA topoisomerase I [Alicyclobacillus acidocaldarius].	27.75	436	257	13	41	457	218	614	7e-26	120
rs:WP_048152983	DNA topoisomerase I [Methanolacinia paynteri].	25.11	446	277	16	18	449	216	618	7e-26	121
rs:WP_041473510	hypothetical protein, partial [Bifidobacterium breve].	27.11	461	284	13	17	445	141	581	7e-26	120
tr:J9FSD0_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central domain protein {ECO:0000313|EMBL:EJW97866.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EJW97866.1}; Flags: Fragment;	31.98	247	151	6	157	399	26	259	7e-26	115
rs:WP_005344197	DNA topoisomerase III [[Eubacterium] hallii].	28.48	330	216	7	74	398	262	576	7e-26	120
rs:WP_014406775	DNA topoisomerase I [Methanocella conradii].	25.29	427	263	14	40	454	236	618	7e-26	120
rs:WP_044231743	DNA topoisomerase I [Porphyromonas sp. COT-290 OH3588].	27.25	422	284	12	18	428	217	626	7e-26	120
rs:WP_043895620	DNA topoisomerase I, partial [Porphyromonas gingivalis].	28.83	326	218	8	60	377	9	328	7e-26	118
rs:WP_031905008	DNA topoisomerase III, partial [Staphylococcus aureus].	28.52	298	190	9	162	454	6	285	8e-26	117
rs:WP_028898404	DNA topoisomerase I [Prevotella sp. HUN102].	27.43	401	268	11	37	427	238	625	8e-26	120
rs:WP_012744292	MULTISPECIES: DNA topoisomerase III [Clostridiales].	28.48	330	216	7	74	398	262	576	8e-26	120
rs:WP_003830724	DNA topoisomerase III [Bifidobacterium breve].	28.89	443	261	18	47	452	240	665	8e-26	120
rs:WP_031796200	DNA topoisomerase III, partial [Staphylococcus aureus].	27.27	319	212	6	57	373	59	359	8e-26	117
rs:WP_002362705	DNA topoisomerase [Enterococcus faecium].	28.14	334	210	7	68	397	281	588	8e-26	120
rs:WP_039635672	hypothetical protein [Clostridium argentinense].	26.69	356	234	9	54	385	158	510	9e-26	119
rs:WP_038041147	DNA topoisomerase I [Thermus tengchongensis].	27.38	442	244	16	36	454	244	631	9e-26	120
rs:WP_019550692	DNA topoisomerase I [Thermus scotoductus].	27.29	447	250	15	36	454	237	636	9e-26	120
rs:WP_031895793	DNA topoisomerase III, partial [Staphylococcus aureus].	28.52	298	190	9	162	454	28	307	9e-26	117
rs:WP_038031619	DNA topoisomerase I [Thermus sp. NMX2.A1].	27.68	448	247	16	36	454	218	617	9e-26	120
rs:WP_032542490	DNA topoisomerase I [Bacteroides fragilis].	26.90	368	230	9	60	425	209	539	9e-26	120
rs:WP_004313592	DNA topoisomerase, partial [Bacteroides xylanisolvens].	31.73	312	192	10	120	427	2	296	1e-25	117
rs:WP_022399462	DNA topoisomerase III [Roseburia sp. CAG:471].	28.96	366	217	13	79	426	264	604	1e-25	120
rs:WP_038821518	hypothetical protein [Pseudomonas syringae].	40.13	152	91	0	255	406	17	168	1e-25	114
rs:WP_003817179	DNA topoisomerase III [Bifidobacterium bifidum].	31.15	366	212	11	47	379	240	598	1e-25	120
rs:WP_009530028	DNA topoisomerase III [Peptostreptococcaceae bacterium CM5].	30.73	371	229	11	31	398	222	567	1e-25	119
rs:WP_028086447	DNA topoisomerase III [Dorea longicatena].	27.20	386	238	10	74	445	262	618	1e-25	120
rs:WP_039433724	DNA topoisomerase I [Porphyromonas gulae].	29.01	355	237	9	74	426	273	614	1e-25	120
rs:WP_036849905	DNA topoisomerase I [Porphyromonas macacae].	29.30	355	236	10	74	426	273	614	1e-25	120
rs:WP_016171183	hypothetical protein, partial [Enterococcus faecium].	33.33	213	130	4	156	365	9	212	1e-25	117
rs:WP_042253559	hypothetical protein [Lactobacillus brevis].	27.18	401	234	13	74	454	280	642	1e-25	120
rs:WP_039106749	hypothetical protein [Lactobacillus brevis].	27.64	398	236	13	74	454	279	641	1e-25	120
rs:WP_010782788	hypothetical protein, partial [Enterococcus faecium].	33.33	213	130	4	156	365	3	206	1e-25	117
tr:A0A076VXS8_BACMY	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:AIK35346.1};	27.53	316	206	7	146	454	1	300	1e-25	119
rs:WP_032825177	topoisomerase I, partial [Oenococcus oeni].	33.22	283	158	11	33	302	46	310	1e-25	116
rs:WP_036887859	hypothetical protein, partial [Prevotella bivia].	28.80	316	203	7	113	426	1	296	1e-25	117
rs:WP_032492066	DNA topoisomerase III, partial [Vibrio cholerae].	35.64	188	112	4	278	459	8	192	1e-25	114
tr:A0A0B8VBY9_9PSED	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGS11352.1}; Flags: Fragment;	34.19	234	126	7	242	459	1	222	1e-25	115
rs:WP_013413259	DNA topoisomerase I [Methanothermus fervidus].	26.71	453	279	14	11	453	215	624	1e-25	120
rs:WP_014546985	DNA topoisomerase [Fibrobacter succinogenes].	31.40	344	198	11	61	377	288	620	1e-25	120
rs:WP_031325380	DNA topoisomerase III, partial [Pseudomonas taiwanensis].	39.61	154	93	0	255	408	4	157	1e-25	113
rs:WP_015718165	DNA topoisomerase I [Thermus scotoductus].	27.29	447	250	15	36	454	218	617	1e-25	120
rs:WP_033563343	DNA topoisomerase I [Sphingobacteriaceae bacterium DW12].	27.02	396	257	8	44	427	256	631	1e-25	120
rs:WP_048106899	DNA topoisomerase I [Methanosarcina barkeri].	25.39	445	272	16	24	454	231	629	1e-25	120
rs:WP_048092634	DNA topoisomerase I [Geoglobus acetivorans].	26.24	404	250	12	56	454	252	612	1e-25	119
rs:WP_022833319	DNA topoisomerase III [Cytophagales bacterium B6].	26.69	341	232	10	57	393	265	591	1e-25	119
rs:WP_002348936	DNA topoisomerase, partial [Enterococcus faecium].	33.33	213	130	4	156	365	28	231	1e-25	117
rs:WP_047021469	hypothetical protein [Lactobacillus brevis].	27.68	401	232	14	74	454	279	641	1e-25	120
rs:WP_032821696	topoisomerase I, partial [Oenococcus oeni].	33.22	283	158	11	33	302	46	310	1e-25	116
rs:WP_013979502	DNA topoisomerase [Eggerthella sp. YY7918].	27.63	427	267	13	40	459	296	687	1e-25	120
rs:WP_031672442	hypothetical protein [Listeria monocytogenes].	26.53	392	253	12	59	433	271	644	1e-25	120
rs:WP_028986563	DNA topoisomerase I [Thermicanus aegyptius].	26.80	459	246	16	34	457	210	613	1e-25	119
rs:WP_047287793	DNA topoisomerase III [Bifidobacterium bifidum].	30.29	373	220	11	40	379	233	598	2e-25	120
rs:WP_044193063	DNA topoisomerase I, partial [Parabacteroides gordonii].	31.66	259	165	6	71	328	141	388	2e-25	117
rs:WP_013815808	DNA topoisomerase I [Porphyromonas gingivalis].	26.60	421	286	12	18	427	217	625	2e-25	119
tr:E1X628_HALMS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.74	439	269	13	41	452	292	700	2e-25	120
rs:WP_003181746	MULTISPECIES: DNA topoisomerase I [Bacillus].	26.70	427	254	15	50	457	227	613	2e-25	119
rs:WP_013352247	DNA topoisomerase I [Bacillus amyloliquefaciens].	26.98	430	251	15	49	457	226	613	2e-25	119
rs:WP_021663186	DNA topoisomerase, partial [Porphyromonas gingivalis].	27.76	371	251	10	18	377	217	581	2e-25	119
rs:WP_031669330	hypothetical protein [Listeria monocytogenes].	26.53	392	253	12	59	433	271	644	2e-25	119
rs:WP_029420516	DNA topoisomerase I [Alicyclobacillus macrosporangiidus].	25.85	441	270	12	36	457	213	615	2e-25	119
rs:WP_002354343	DNA topoisomerase, partial [Enterococcus faecium].	34.47	206	123	4	163	365	2	198	2e-25	116
rs:WP_027108419	DNA topoisomerase I [Lacticigenium naphtae].	26.30	441	261	17	34	452	211	609	2e-25	119
tr:S2ZM87_BIFBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EPD75485.1};	28.19	447	259	17	47	452	240	665	2e-25	119
rs:WP_032111009	DNA topoisomerase [bacterium OL-1].	27.29	414	244	12	60	459	310	680	2e-25	120
rs:WP_033892104	DNA topoisomerase III [Bifidobacterium saguini].	28.57	441	276	16	27	445	219	642	2e-25	119
rs:WP_031378741	DNA topoisomerase I [Bacillus amyloliquefaciens].	27.44	430	249	16	49	457	226	613	2e-25	119
rs:WP_005588136	DNA topoisomerase I [Clostridium ultunense].	26.80	459	246	16	34	457	210	613	2e-25	119
rs:WP_004364080	DNA topoisomerase III [Prevotella nigrescens].	29.40	398	246	14	44	427	249	625	2e-25	119
rs:WP_014470402	MULTISPECIES: DNA topoisomerase I [Bacillus subtilis group].	26.98	430	251	15	49	457	226	613	2e-25	119
rs:WP_005681887	DNA topoisomerase I [Bacteroides caccae].	26.36	368	232	9	60	425	209	539	2e-25	119
rs:WP_032734795	DNA topoisomerase III, partial [Bifidobacterium breve].	28.19	447	259	17	47	452	240	665	2e-25	119
rs:WP_019819801	hypothetical protein, partial [Vibrio splendidus].	37.41	147	92	0	31	177	60	206	2e-25	113
rs:WP_020210913	hypothetical protein [Gilvimarinus chinensis].	25.34	438	271	13	35	459	207	601	2e-25	119
rs:WP_021985356	DNA topoisomerase [Clostridium sp. CAG:127].	26.37	421	253	12	48	452	221	600	2e-25	119
rs:WP_044558127	hypothetical protein, partial [Halobacteriovorax marinus].	25.74	439	269	13	41	452	278	686	2e-25	119
rs:WP_041877376	DNA topoisomerase I [Pedobacter sp. NL19].	26.91	327	224	9	59	382	267	581	2e-25	119
rs:WP_004351990	DNA topoisomerase I [Prevotella denticola].	26.20	416	273	11	30	434	232	624	2e-25	119
rs:WP_042706517	DNA topoisomerase I [Methanomicrobium mobile].	25.42	421	262	14	39	449	240	618	3e-25	119
tr:L9PR83_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELX66133.1};	35.78	218	135	4	160	375	2	216	3e-25	115
rs:WP_019968966	DNA topoisomerase I [Prevotella maculosa].	26.20	416	273	11	30	434	232	624	3e-25	119
tr:A0A0B8NR71_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAM54802.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAM54802.1};	38.93	149	83	1	200	348	2	142	3e-25	111
rs:WP_040146912	DNA topoisomerase III, partial [Xanthomonas citri].	34.81	181	109	4	274	454	6	177	3e-25	112
rs:WP_023058387	MULTISPECIES: DNA topoisomerase [Prevotella].	28.29	403	256	13	40	427	241	625	3e-25	119
tr:K1SPC5_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central domain protein {ECO:0000313|EMBL:EKC62512.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EKC62512.1}; Flags: Fragment;	33.06	242	139	8	160	392	11	238	3e-25	113
rs:WP_034548728	DNA topoisomerase I [Carnobacterium alterfunditum].	26.53	426	256	14	50	457	228	614	3e-25	119
rs:WP_004591511	DNA topoisomerase I [Haloarcula japonica].	24.54	432	281	11	31	454	236	630	3e-25	119
rs:WP_005798105	DNA topoisomerase I [Bacteroides fragilis].	26.36	368	232	9	60	425	209	539	3e-25	118
rs:WP_047090595	DNA topoisomerase III, partial [Escherichia coli].	32.64	193	126	1	37	229	245	433	3e-25	116
rs:WP_031922917	DNA topoisomerase III, partial [Staphylococcus aureus].	27.24	323	215	6	57	377	268	572	3e-25	118
rs:WP_031907700	DNA topoisomerase III, partial [Staphylococcus aureus].	28.16	277	182	6	160	427	18	286	4e-25	115
rs:WP_014345297	DNA topoisomerase I [Sulfobacillus acidophilus].	27.89	441	264	15	35	454	213	620	4e-25	118
tr:F8I2K1_SULAT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.28	442	261	16	35	454	204	611	4e-25	118
rs:WP_012514069	DNA topoisomerase III [Hydrogenobaculum sp. Y04AAS1].	25.61	371	217	6	55	385	291	642	4e-25	119
tr:R2NT98_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOH42604.1};	33.49	209	127	4	160	365	2	201	4e-25	115
rs:WP_022362848	DNA topoisomerase type IA central domain protein [Eggerthella sp. CAG:298].	28.00	425	254	13	47	459	293	677	4e-25	119
rs:WP_025070722	DNA topoisomerase I [Prevotella oulorum].	26.60	421	286	11	18	427	217	625	4e-25	118
tr:C9CG38_ENTFC	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEV43554.1};	33.49	209	127	4	160	365	2	201	4e-25	115
tr:A0A0B8PFG7_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	38.97	136	83	0	35	170	196	331	4e-25	115
rs:WP_033629029	DNA topoisomerase, partial [Enterococcus faecium].	33.33	213	130	4	156	365	6	209	4e-25	115
rs:WP_007409771	MULTISPECIES: DNA topoisomerase I [Bacillus].	27.21	430	250	16	49	457	226	613	4e-25	118
tr:I2HR12_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.21	430	250	16	49	457	228	615	4e-25	118
rs:WP_044345962	DNA topoisomerase III, partial [Pseudomonas meliae].	39.22	153	85	1	260	404	2	154	4e-25	113
tr:C7DGI7_MICA2	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.34	428	267	14	35	454	239	630	4e-25	118
rs:WP_016936131	DNA topoisomerase I [Bacillus siamensis].	27.21	430	250	16	49	457	226	613	4e-25	118
rs:WP_020451381	MULTISPECIES: DNA topoisomerase I [Bacillus].	26.46	427	255	15	50	457	227	613	4e-25	118
rs:WP_045926121	MULTISPECIES: DNA topoisomerase I [Bacillus].	27.21	430	250	16	49	457	226	613	4e-25	118
rs:WP_021725319	DNA topoisomerase I [Olsenella profusa].	27.82	435	246	16	40	454	293	679	4e-25	118
rs:WP_029325907	MULTISPECIES: DNA topoisomerase I [Bacillus].	27.21	430	250	16	49	457	226	613	5e-25	118
rs:WP_009304728	MULTISPECIES: DNA topoisomerase [Eggerthella].	26.93	427	270	12	40	459	286	677	5e-25	118
tr:K1UET1_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC78504.1}; Flags: Fragment;	31.95	266	157	7	27	287	23	269	5e-25	114
rs:WP_033795164	DNA topoisomerase, partial [Enterococcus faecium].	33.33	213	130	4	156	365	22	225	5e-25	115
rs:WP_027089858	DNA topoisomerase III [[Clostridium] saccharogumia].	27.93	333	214	7	74	398	262	576	5e-25	118
tr:J7AQD8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.17	258	163	5	57	311	15	263	5e-25	113
tr:T0YYR8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD40801.1}; Flags: Fragment;	43.66	142	77	3	27	168	70	208	5e-25	112
rs:WP_039198697	DNA topoisomerase III [Bifidobacterium kashiwanohense].	29.70	367	215	13	47	379	240	597	5e-25	118
rs:WP_012617952	DNA topoisomerase I [Methanosphaerula palustris].	24.46	417	271	12	40	450	241	619	5e-25	118
rs:WP_002353327	DNA topoisomerase, partial [Enterococcus faecium].	31.80	261	166	5	54	311	126	377	5e-25	115
rs:WP_033524055	DNA topoisomerase III [Bifidobacterium pseudocatenulatum].	30.60	366	210	11	47	377	240	596	5e-25	118
rs:WP_010466538	DNA topoisomerase [Pseudomonas mandelii].	26.67	435	261	17	46	459	230	627	5e-25	118
rs:WP_025649465	DNA topoisomerase I [Bacillus methylotrophicus].	27.21	430	250	16	49	457	226	613	5e-25	118
rs:WP_033692241	hypothetical protein, partial [Bacillus sp. GeD10].	33.33	231	143	6	67	293	278	501	5e-25	116
tr:I2C540_BACAM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.21	430	250	16	49	457	228	615	5e-25	118
rs:WP_014417765	MULTISPECIES: DNA topoisomerase I [Bacillales].	27.21	430	250	16	49	457	226	613	5e-25	118
rs:WP_036611732	DNA topoisomerase III [Oribacterium sp. P6A1].	26.52	445	260	14	40	445	228	644	6e-25	118
rs:WP_003154274	MULTISPECIES: DNA topoisomerase I [Bacillus].	27.21	430	250	16	49	457	226	613	6e-25	118
rs:WP_047865166	hypothetical protein, partial [Rubrobacter aplysinae].	29.73	407	231	14	60	453	263	627	6e-25	117
rs:WP_031897066	DNA topoisomerase III, partial [Staphylococcus aureus].	27.68	289	191	8	113	396	1	276	6e-25	114
rs:WP_039423446	DNA topoisomerase I [Porphyromonas gulae].	28.73	355	238	9	74	426	273	614	6e-25	117
rs:WP_010642515	DNA topoisomerase I [Acidithiobacillus thiooxidans].	28.26	414	247	13	43	445	227	601	7e-25	117
rs:WP_002585004	MULTISPECIES: DNA topoisomerase III [Clostridiales].	26.72	363	234	10	79	428	264	607	7e-25	117
rs:WP_021676799	DNA topoisomerase [Porphyromonas gingivalis].	26.37	421	287	12	18	427	217	625	7e-25	117
rs:WP_006573547	hypothetical protein [Pseudoflavonifractor capillosus].	29.34	242	164	5	47	286	235	471	7e-25	116
rs:WP_031834052	DNA topoisomerase III, partial [Staphylococcus aureus].	28.19	298	191	9	162	454	22	301	7e-25	114
tr:D5Q4K0_PEPDI	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFH07133.1};	26.72	363	234	10	79	428	267	610	7e-25	117
rs:WP_016526770	DNA topoisomerase [Lactobacillus plantarum].	30.33	366	232	8	29	385	237	588	8e-25	117
tr:C3J9A0_9PORP	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEN83247.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EEN83247.1};	27.84	352	239	8	35	377	123	468	8e-25	117
tr:S4NKE1_9PORP	SubName: Full=DNA topoisomerase III, Bacteroidales-type {ECO:0000313|EMBL:GAD07880.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAD07880.1};	26.78	366	248	9	70	427	6	359	8e-25	115
tr:I7BY88_PSEPT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AFO49117.1};	38.96	154	94	0	255	408	8	161	8e-25	111
rs:WP_033500273	hypothetical protein [Bifidobacterium stercoris].	26.74	445	266	14	39	445	232	654	8e-25	117
rs:WP_013867618	DNA topoisomerase I [Methanothermococcus okinawensis].	27.87	409	207	15	77	454	279	630	8e-25	117
rs:WP_048062414	DNA topoisomerase I, partial [Methanococcus aeolicus].	25.59	465	276	17	11	454	221	636	8e-25	117
rs:WP_020795116	hypothetical protein [Pseudomonas sp. G5(2012)].	26.67	435	255	14	49	459	233	627	8e-25	117
rs:WP_011972751	DNA topoisomerase I [Methanococcus aeolicus].	25.59	465	276	17	11	454	221	636	9e-25	117
tr:D6CZ79_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.36	368	232	9	60	425	209	539	9e-25	117
tr:A0A087DS06_9BIFI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KFI98306.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KFI98306.1};	26.74	445	266	14	39	445	244	666	9e-25	117
rs:WP_035052659	DNA topoisomerase I [Carnobacterium pleistocenium].	26.53	426	256	14	50	457	228	614	9e-25	117
tr:C0AQN3_9ENTR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEG87686.1};	40.27	149	83	1	228	376	25	167	9e-25	111
rs:WP_012810735	DNA topoisomerase I [Alicyclobacillus acidocaldarius].	27.75	436	257	14	41	457	218	614	9e-25	117
rs:WP_042975774	DNA topoisomerase 1 [Bacillus subtilis].	26.93	427	253	16	50	457	227	613	9e-25	117
rs:WP_014663959	MULTISPECIES: DNA topoisomerase I [Bacillus].	26.70	427	254	16	50	457	227	613	9e-25	117
rs:WP_013922222	DNA topoisomerase I [Francisella sp. TX077308].	27.30	403	244	12	67	452	252	622	9e-25	117
rs:WP_040580315	DNA topoisomerase I [Porphyromonas endodontalis].	27.84	352	239	8	35	377	161	506	9e-25	117
rs:WP_021479296	DNA topoisomerase 1 [Bacillus sp. EGD-AK10].	26.93	427	253	16	50	457	227	613	1e-24	117
rs:WP_017168565	hypothetical protein, partial [Xanthomonas axonopodis].	51.79	112	54	0	30	141	237	348	1e-24	114
rs:WP_034881273	DNA topoisomerase III [Bifidobacterium pseudocatenulatum].	30.33	366	211	11	47	377	240	596	1e-24	117
rs:WP_046381022	DNA topoisomerase I [Bacillus sp. LM 4-2].	26.93	427	253	16	50	457	227	613	1e-24	117
gp:CP003695_2276	DNA topoisomerase I [Bacillus subtilis subsp. subtilis str. BSP1]	26.93	427	253	16	50	457	232	618	1e-24	117
rs:WP_038428950	DNA topoisomerase I [Bacillus subtilis].	26.93	427	253	16	50	457	227	613	1e-24	117
rs:WP_003622318	DNA topoisomerase I [Komagataeibacter hansenii].	28.01	457	267	15	28	452	213	639	1e-24	117
sp:TOP1_BACSU	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	26.93	427	253	16	50	457	227	613	1e-24	117
rs:WP_029070660	DNA topoisomerase I [Kandleria vitulina].	27.67	412	237	10	60	455	237	603	1e-24	117
rs:WP_038071896	DNA topoisomerase I [Thermus scotoductus].	27.03	455	249	16	36	454	218	625	1e-24	117
rs:WP_026965596	DNA topoisomerase I [Alicyclobacillus pomorum].	24.49	441	276	11	36	457	213	615	1e-24	117
rs:WP_008036521	DNA topoisomerase I [Rhodobacterales bacterium HTCC2255].	28.47	432	247	16	47	452	231	626	1e-24	117
rs:WP_023983524	hypothetical protein [Prevotella oralis].	25.85	383	252	9	61	434	265	624	1e-24	117
rs:WP_031588933	DNA topoisomerase I [Kandleria vitulina].	27.67	412	237	10	60	455	237	603	1e-24	117
rs:WP_009751280	DNA topoisomerase [Capnocytophaga sp. oral taxon 332].	27.71	415	259	14	60	452	262	657	1e-24	117
rs:WP_020057405	DNA topoisomerase I [alpha proteobacterium SCGC AAA076-C03].	28.47	432	247	16	47	452	231	626	1e-24	117
rs:WP_046999514	hypothetical protein [Bifidobacterium adolescentis].	27.01	448	261	15	39	445	232	654	1e-24	117
gp:CP002906_1692	DNA topoisomerase I [Bacillus subtilis subsp. subtilis str. RO-NN-1]	26.93	427	253	16	50	457	229	615	1e-24	117
tr:G4EWD2_BACIU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.93	427	253	16	50	457	220	606	1e-24	117
rs:WP_014298129	DNA topoisomerase I [Bacteroides fragilis].	27.76	371	251	10	18	377	217	581	1e-24	117
rs:WP_036875017	hypothetical protein, partial [Prevotella nigrescens].	31.29	278	168	8	113	384	1	261	1e-24	114
rs:WP_023787408	DNA topoisomerase I [Hyphomicrobium nitrativorans].	29.81	426	227	16	70	452	254	650	1e-24	117
rs:WP_028782775	DNA topoisomerase I [Thalassobacillus devorans].	26.28	430	258	14	47	457	224	613	1e-24	117
rs:WP_004517003	DNA topoisomerase I [Haloarcula vallismortis].	24.81	403	258	11	60	454	265	630	1e-24	117
rs:WP_008646106	hypothetical protein, partial [Bacteroides sp. 1_1_30].	31.61	310	191	10	122	427	1	293	1e-24	114
rs:WP_026398617	DNA topoisomerase I [Acetobacter nitrogenifigens].	27.29	425	249	14	59	452	241	636	1e-24	117
rs:WP_048126945	DNA topoisomerase I [Methanosarcina sp. WH1].	26.29	445	262	16	27	454	234	629	1e-24	117
rs:WP_048064469	DNA topoisomerase I [Archaeoglobus fulgidus].	26.57	414	256	15	47	454	242	613	1e-24	116
rs:WP_043857492	DNA topoisomerase 1 [Bacillus subtilis].	26.93	427	253	16	50	457	227	613	1e-24	116
tr:D4FWK7_BACNB	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.53	426	256	15	50	457	229	615	2e-24	116
rs:WP_014479776	DNA topoisomerase I [Bacillus subtilis].	26.53	426	256	15	50	457	227	613	2e-24	116
tr:A0A0F0A875_BACIU	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJJ42893.1};	26.30	441	262	16	35	457	218	613	2e-24	116
rs:WP_036889583	DNA topoisomerase I [Porphyromonas crevioricanis].	28.68	394	254	13	44	427	249	625	2e-24	116
rs:WP_017706786	DNA topoisomerase III, partial [Pseudomonas syringae].	40.48	126	72	1	47	172	256	378	2e-24	113
rs:WP_028394567	DNA topoisomerase I [Bacillus sp. FJAT-14578].	26.02	488	286	19	1	457	170	613	2e-24	116
sp:TOP1_ARCFU	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	26.57	414	256	15	47	454	244	615	2e-24	116
tr:A0A0F2WYH0_SALET	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KJT41428.1};	38.31	154	89	1	232	385	5	152	2e-24	110
rs:WP_002997248	transposase [Sphingobacterium spiritivorum].	28.78	337	212	10	70	391	272	595	2e-24	116
rs:WP_045716599	DNA topoisomerase III, partial [Salmonella enterica].	38.31	154	89	1	232	385	5	152	2e-24	110
rs:WP_048407237	DNA topoisomerase I [Bacillus sp. KJ-17].	26.23	427	256	15	50	457	226	612	2e-24	116
rs:WP_039422551	DNA topoisomerase I [Porphyromonas gulae].	26.42	371	256	9	18	377	217	581	2e-24	116
tr:G0QAX5_NANSJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.75	400	242	13	70	454	272	631	2e-24	116
rs:WP_048196118	DNA topoisomerase [Methanococcoides methylutens].	26.80	444	269	16	31	454	235	642	2e-24	116
rs:WP_022468181	DNA topoisomerase [Acidaminococcus sp. CAG:917].	26.17	470	236	16	47	449	224	649	2e-24	116
rs:WP_048155452	DNA topoisomerase I [Methanosarcina sp. Kolksee].	26.43	401	241	15	66	454	271	629	2e-24	116
rs:WP_036575662	DNA topoisomerase [Olsenella uli].	26.67	435	261	12	40	459	293	684	2e-24	116
rs:WP_022166320	DNA topoisomerase [Eubacterium sp. CAG:192].	30.82	279	151	10	155	393	11	287	2e-24	112
rs:WP_034490094	DNA topoisomerase III [Butyrivibrio fibrisolvens].	28.61	374	230	12	47	396	235	595	2e-24	115
rs:WP_048166503	DNA topoisomerase I [Methanosarcina thermophila].	25.00	440	280	13	24	454	232	630	3e-24	116
rs:WP_004341621	DNA topoisomerase I [Prevotella buccae].	26.37	421	287	11	18	427	217	625	3e-24	116
rs:WP_013252301	DNA topoisomerase [Olsenella uli].	26.67	435	261	12	40	459	293	684	3e-24	116
rs:WP_048140117	DNA topoisomerase I [Methanosarcina horonobensis].	25.85	410	251	14	56	454	262	629	3e-24	115
tr:E1L2T0_9ACTN	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.02	439	256	17	37	459	305	699	3e-24	116
rs:WP_032849199	DNA topoisomerase III, partial [Mannheimia haemolytica].	34.76	164	98	3	294	457	1	155	3e-24	108
gp:AF042825_1	DNA topoisomerase I [Pyrococcus furiosus]	29.36	361	205	13	112	457	563	888	3e-24	116
rs:WP_048158864	DNA topoisomerase I [Methanosarcina sp. WWM596].	26.07	445	263	16	27	454	234	629	3e-24	115
rs:WP_019962158	DNA topoisomerase I [Woodsholea maritima].	27.44	441	261	14	41	454	224	632	3e-24	116
rs:WP_020448704	DNA topoisomerase I [Candidatus Methanomassiliicoccus intestinalis].	25.06	447	280	14	23	454	218	624	3e-24	115
tr:I4Z0W6_9RHIZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.85	316	207	7	40	336	245	558	3e-24	115
rs:WP_040327148	DNA topoisomerase, partial [Atopobium vaginae].	28.02	439	256	17	37	459	305	699	3e-24	116
rs:WP_039073950	DNA topoisomerase I [Bacillus sp. MSP13].	26.24	442	261	17	35	457	218	613	3e-24	115
rs:WP_014464133	DNA topoisomerase I [Alicyclobacillus acidocaldarius].	27.87	427	250	14	50	457	227	614	4e-24	115
rs:WP_046128972	DNA topoisomerase I [Bacillus sp. TH008].	26.23	427	256	15	50	457	227	613	4e-24	115
rs:WP_019714400	DNA topoisomerase I [Bacillus subtilis].	26.46	427	255	16	50	457	227	613	4e-24	115
tr:W1EWP4_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	42.19	128	73	1	36	163	251	377	4e-24	113
rs:WP_048120370	DNA topoisomerase I [Methanosarcina vacuolata].	25.11	442	277	15	24	454	231	629	4e-24	115
rs:WP_015325136	topoisomerase IA [Methanomethylovorans hollandica].	26.53	441	274	14	31	454	248	655	4e-24	115
rs:WP_010331111	DNA topoisomerase I [Bacillus vallismortis].	26.24	442	261	17	35	457	218	613	4e-24	115
sp:TOP1_PYRFU	RecName: Full=DNA topoisomerase 1; EC=5.99.1.2; AltName: Full=DNA topoisomerase I; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme; Contains: RecName: Full=Endonuclease PI-PfuI; EC=3.1.-.-; AltName: Full=Pfu topA intein;	29.28	362	204	14	112	457	689	1014	4e-24	115
rs:XP_008162976	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Chrysemys picta bellii].	28.31	445	252	17	39	455	202	607	4e-24	115
rs:XP_008162975	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Chrysemys picta bellii].	28.31	445	252	17	39	455	290	695	4e-24	115
rs:WP_013194169	DNA topoisomerase I [Methanohalobium evestigatum].	25.50	447	271	15	24	454	227	627	5e-24	115
rs:WP_005878152	DNA topoisomerase I [Enterococcus durans].	26.12	448	263	14	34	457	211	614	5e-24	115
rs:WP_046864111	DNA topoisomerase [Microvirga sp. JC119].	29.36	327	205	9	70	371	274	599	5e-24	115
rs:WP_038048163	DNA topoisomerase I [Thermus caliditerrae].	27.38	442	244	17	36	454	244	631	5e-24	115
rs:WP_040638147	DNA topoisomerase, partial [Microvirga lotononidis].	27.85	316	207	7	40	336	236	549	5e-24	114
rs:YP_008636850	hypothetical protein XFF4834R_pla00220 (plasmid) [Xanthomonas fuscans subsp. fuscans].	36.87	179	103	5	77	248	1	176	5e-24	108
rs:WP_040152282	DNA topoisomerase III, partial [Xanthomonas citri].	30.77	221	139	3	218	431	7	220	5e-24	109
rs:WP_019192864	hypothetical protein, partial [Anaerococcus pacaensis].	29.97	307	184	9	98	398	2	283	5e-24	110
rs:WP_019152799	DNA topoisomerase I [Bacillus massiliosenegalensis].	26.87	428	255	15	49	457	226	614	5e-24	115
tr:R7TJU1_CAPTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.77	437	260	12	39	451	257	657	5e-24	115
rs:WP_045488834	DNA topoisomerase [Bacillus sp. TS-2].	25.06	407	270	13	54	450	266	647	6e-24	115
rs:WP_035561877	hypothetical protein [Halomonas sp. KO116].	30.89	369	205	17	62	399	292	641	6e-24	115
rs:WP_042744585	topoisomerase I, partial [Oenococcus oeni].	33.05	239	125	9	77	302	1	217	6e-24	109
rs:WP_041907184	MULTISPECIES: DNA topoisomerase I [Bacillus].	26.46	427	255	16	50	457	227	613	6e-24	115
rs:WP_036141355	DNA topoisomerase I [Lysinibacillus sp. BF-4].	27.23	437	250	18	40	452	217	609	6e-24	115
rs:WP_006056449	DNA topoisomerase I [Halogeometricum borinquense].	24.07	403	261	11	60	454	271	636	6e-24	115
rs:WP_007724946	DNA topoisomerase I [Carnobacterium sp. AT7].	26.06	426	258	13	50	457	228	614	6e-24	115
rs:WP_018932685	DNA topoisomerase I [Gracilibacillus lacisalsi].	25.52	431	261	15	47	457	224	614	6e-24	115
rs:WP_034428120	DNA topoisomerase, partial [Anaerococcus pacaensis].	29.97	307	184	8	98	398	2	283	6e-24	110
tr:M4KRT9_BACIU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.70	427	254	16	50	457	229	615	6e-24	114
rs:WP_046833762	hypothetical protein [Xanthomonas axonopodis].	36.87	179	103	5	77	248	1	176	6e-24	108
rs:WP_026586954	DNA topoisomerase I [Bacillus sp. NSP9.1].	25.76	427	258	15	50	457	227	613	6e-24	114
rs:WP_024716065	DNA topoisomerase I [Bacillus tequilensis].	26.30	441	262	16	35	457	218	613	6e-24	114
tr:A0A0E9DR26_CHLTH	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CRH60597.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRH60597.1};	27.88	416	241	14	59	459	313	684	6e-24	115
rs:WP_041517853	DNA topoisomerase I [Bacillus subtilis].	26.70	427	254	16	50	457	227	613	6e-24	114
rs:WP_047338920	hypothetical protein [Enterococcus cecorum].	28.06	360	219	10	61	411	271	599	7e-24	114
rs:WP_039688410	DNA topoisomerase [Coriobacteriaceae bacterium 68-1-3].	26.55	403	249	12	67	459	313	678	7e-24	115
rs:WP_048193920	DNA topoisomerase I [Methanococcoides methylutens].	25.28	451	281	16	18	454	216	624	7e-24	114
rs:WP_026601896	DNA topoisomerase I [Methylomonas sp. 11b].	29.56	433	236	17	46	452	234	623	7e-24	115
rs:WP_002358260	DNA topoisomerase, partial [Enterococcus faecium].	33.50	206	125	4	163	365	2	198	7e-24	110
rs:WP_048152545	endonuclease [Palaeococcus ferrophilus].	28.76	386	203	13	112	457	828	1181	7e-24	115
rs:WP_033694419	hypothetical protein [Bacillus thuringiensis].	28.00	300	180	7	160	450	2	274	7e-24	111
rs:WP_004066811	DNA topoisomerase I [Thermococcus litoralis].	29.48	346	149	11	166	457	54	358	7e-24	112
rs:WP_033337307	hypothetical protein, partial [Thioalkalivibrio thiocyanodenitrificans].	33.16	196	126	3	38	233	238	428	7e-24	112
rs:WP_040746384	DNA topoisomerase III, partial [alpha proteobacterium BAL199].	36.14	202	116	4	221	414	2	198	7e-24	112
rs:WP_048178837	DNA topoisomerase I [Methanosarcina sp. MTP4].	25.45	440	246	17	40	454	247	629	7e-24	114
rs:WP_021900264	DNA topoisomerase type IA central domain protein [Eggerthella sp. CAG:1427].	25.22	464	302	12	6	459	249	677	7e-24	115
rs:WP_005601674	DNA topoisomerase III [Butyrivibrio crossotus].	27.14	350	216	8	69	396	260	592	8e-24	114
rs:WP_048117881	DNA topoisomerase I [Methanosarcina barkeri].	26.49	404	237	16	66	454	271	629	8e-24	114
rs:WP_029276016	DNA topoisomerase I [Carnobacterium jeotgali].	26.06	426	258	13	50	457	228	614	8e-24	114
rs:WP_015324220	DNA topoisomerase I, archaeal [Methanomethylovorans hollandica].	25.06	427	264	14	40	454	243	625	8e-24	114
rs:WP_012457228	DNA topoisomerase I [Porphyromonas gingivalis].	27.56	352	240	8	35	377	236	581	8e-24	114
rs:WP_014113782	DNA topoisomerase I [Bacillus subtilis].	26.23	427	256	16	50	457	227	613	8e-24	114
rs:WP_024728265	MULTISPECIES: DNA topoisomerase III [unclassified Clostridiales (miscellaneous)].	27.88	330	218	7	74	398	262	576	8e-24	114
rs:WP_027883605	DNA topoisomerase I [Meiothermus rufus].	28.54	410	220	15	61	452	246	600	9e-24	114
rs:WP_026799764	DNA topoisomerase I [Pontibacillus halophilus].	25.64	429	263	13	47	457	224	614	9e-24	114
rs:WP_036889264	hypothetical protein, partial [Prevotella aurantiaca].	28.71	317	200	8	113	425	1	295	9e-24	111
rs:WP_008824362	hypothetical protein, partial [Prevotella histicola].	28.83	274	183	6	154	425	18	281	9e-24	111
tr:A0A0B3AAN5_9ARCH	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KHO49463.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KHO49463.1};	26.22	431	264	15	38	453	163	554	9e-24	114
tr:E9H1M6_DAPPU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.56	439	249	18	41	450	261	659	9e-24	114
rs:WP_021842395	DNA topoisomerase [Veillonella sp. CAG:933].	36.60	194	90	5	293	454	1	193	9e-24	110
rs:WP_009182186	DNA topoisomerase I [Desulfovibrio sp. FW1012B].	28.41	433	245	18	41	459	220	601	9e-24	114
rs:WP_008389044	DNA topoisomerase I [Halogeometricum pallidum].	25.18	425	270	13	40	454	250	636	9e-24	114
rs:WP_003220843	DNA topoisomerase I [Bacillus subtilis].	26.23	427	256	16	50	457	227	613	9e-24	114
rs:WP_021250287	DNA topoisomerase I [Thauera terpenica].	28.01	407	238	16	63	459	238	599	1e-23	114
rs:WP_048155369	DNA topoisomerase I [Methanosarcina barkeri].	26.49	404	237	16	66	454	271	629	1e-23	114
rs:WP_047334070	hypothetical protein [Enterococcus cecorum].	28.06	360	219	10	61	411	271	599	1e-23	114
rs:WP_013489103	DNA topoisomerase I [Bacillus cellulosilyticus].	27.10	428	241	18	50	452	227	608	1e-23	114
rs:WP_022134546	DNA topoisomerase [Clostridium sp. CAG:594].	25.36	489	263	16	22	450	193	639	1e-23	114
rs:WP_042471896	DNA topoisomerase I [Bacillus sp. FF3].	24.79	484	288	19	1	452	170	609	1e-23	114
rs:WP_048205544	DNA topoisomerase [Methanococcoides methylutens].	25.98	458	269	17	24	454	228	642	1e-23	114
rs:WP_023178015	MULTISPECIES: DNA topoisomerase I [Carnobacterium].	26.06	426	258	14	50	457	228	614	1e-23	114
rs:WP_029418511	DNA topoisomerase I [Bacillus sonorensis].	25.76	427	258	15	50	457	227	613	1e-23	114
tr:T1C850_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD78317.1}; Flags: Fragment;	31.91	188	119	4	47	233	61	240	1e-23	108
tr:A0A0E3SSF2_METMT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:AKB85453.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AKB85453.1};	25.98	458	269	17	24	454	181	595	1e-23	114
rs:WP_036891125	hypothetical protein, partial [Prevotella corporis].	27.85	316	206	7	113	426	1	296	1e-23	111
rs:WP_023567308	DNA topoisomerase III, partial [Escherichia coli].	37.66	154	90	1	232	385	5	152	1e-23	108
rs:WP_036875141	hypothetical protein, partial [Prevotella nigrescens].	28.39	317	201	8	113	425	1	295	1e-23	111
rs:WP_015056179	DNA topoisomerase III [Staphylococcus aureus].	26.54	309	206	6	35	342	248	536	1e-23	113
rs:WP_011498828	DNA topoisomerase [Methanococcoides burtonii].	25.90	444	273	15	31	454	235	642	1e-23	114
rs:WP_036891834	hypothetical protein, partial [Prevotella corporis].	29.93	274	177	5	113	384	1	261	1e-23	110
rs:WP_047090521	DNA topoisomerase III, partial [Escherichia coli].	32.47	194	122	2	248	432	22	215	1e-23	109
rs:WP_006302460	DNA topoisomerase [Atopobium vaginae].	27.64	416	242	14	59	459	313	684	1e-23	114
rs:WP_013748699	endonuclease [Pyrococcus sp. NA2].	29.84	305	171	8	166	457	735	1009	1e-23	114
rs:WP_005538001	DNA topoisomerase I [Haloarcula argentinensis].	24.57	403	259	11	60	454	265	630	1e-23	114
rs:WP_004089715	DNA topoisomerase III [Xylella fastidiosa].	49.18	122	22	2	123	244	3	84	1e-23	104
tr:W1DXM5_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	42.64	129	71	2	36	163	76	202	1e-23	108
rs:WP_035547526	DNA topoisomerase I, partial [Halobacillus sp. BBL2006].	25.35	426	263	12	49	457	226	613	1e-23	113
rs:WP_025692485	hypothetical protein, partial [Paenibacillus zanthoxyli].	36.63	172	106	2	38	207	233	403	1e-23	111
rs:WP_007315375	DNA topoisomerase I [Methanolinea tarda].	25.67	413	255	15	48	449	247	618	1e-23	114
rs:WP_010219002	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	39.05	169	94	2	284	452	9	168	1e-23	107
rs:WP_019969023	DNA topoisomerase I [Prevotella maculosa].	25.45	440	270	12	30	434	232	648	1e-23	114
rs:WP_048091127	DNA topoisomerase I, partial [Candidatus Methanoperedens nitroreducens].	25.93	428	262	15	38	454	235	618	1e-23	114
rs:WP_009366453	DNA topoisomerase I [Halogranum salarium].	25.25	404	255	12	60	454	282	647	1e-23	114
tr:W1FZV9_ECOLX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CDL39904.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDL39904.1};	37.66	154	90	1	232	385	21	168	1e-23	108
rs:WP_003238559	DNA topoisomerase I [Bacillus subtilis].	26.23	427	256	16	50	457	227	613	2e-23	113
rs:WP_044825956	DNA topoisomerase I [Clostridium aceticum].	25.47	428	254	13	47	454	225	607	2e-23	113
tr:A0A062V8Y9_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.93	428	262	15	38	454	235	618	2e-23	113
tr:A0A0B5GGX8_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.57	403	259	11	60	454	265	630	2e-23	114
rs:WP_008637892	MULTISPECIES: DNA topoisomerase I [Bacillaceae].	25.65	421	258	12	54	457	231	613	2e-23	113
rs:WP_011250042	endonuclease [Thermococcus kodakarensis].	28.68	394	200	12	112	457	828	1188	2e-23	114
rs:WP_015590146	DNA topoisomerase I [Archaeoglobus sulfaticallidus].	24.71	425	270	14	38	454	237	619	2e-23	113
rs:WP_014040904	DNA topoisomerase I [Haloarcula hispanica].	24.57	403	259	11	60	454	265	630	2e-23	114
rs:WP_048043245	DNA topoisomerase I [Methanosarcina mazei].	25.24	424	267	14	40	454	247	629	2e-23	113
rs:WP_035505356	MULTISPECIES: DNA topoisomerase I [Halobacillus].	25.89	421	257	12	54	457	231	613	2e-23	113
tr:A0A078MI83_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.77	437	252	17	40	452	217	609	2e-23	113
rs:WP_043928301	DNA topoisomerase I [Bacillus licheniformis].	26.00	427	257	15	50	457	227	613	2e-23	113
rs:WP_042383308	DNA topoisomerase I [Geobacillus thermoglucosidasius].	26.65	439	257	16	41	457	218	613	2e-23	113
tr:M7XYJ7_9RHIZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.65	424	267	13	40	432	227	637	2e-23	113
rs:WP_025002755	DNA topoisomerase I [Prevotella dentasini].	25.84	445	283	12	18	427	217	649	2e-23	113
rs:WP_003251768	MULTISPECIES: DNA topoisomerase I [Geobacillus].	26.65	439	257	16	41	457	218	613	2e-23	113
rs:WP_033694665	DNA topoisomerase III, partial [Bacillus thuringiensis].	32.20	205	135	3	36	237	171	374	2e-23	110
rs:WP_043039283	DNA topoisomerase [Streptococcus equi].	28.61	360	212	12	50	401	253	575	2e-23	112
rs:WP_008312743	DNA topoisomerase I [Haloarcula amylolytica].	24.32	403	260	11	60	454	265	630	2e-23	113
rs:WP_022378698	DNA topoisomerase type IA central domain protein [Cryptobacterium sp. CAG:338].	26.85	391	247	9	74	459	321	677	2e-23	113
rs:WP_021624136	DNA topoisomerase [Aneurinibacillus aneurinilyticus].	26.57	414	242	11	30	427	227	594	2e-23	113
rs:WP_039893601	DNA topoisomerase, partial [Methylobacterium mesophilicum].	26.65	424	267	13	40	432	236	646	2e-23	113
rs:WP_047338674	hypothetical protein [Enterococcus cecorum].	27.89	337	202	11	59	389	266	567	2e-23	112
rs:WP_044996218	DNA topoisomerase III [Lachnospiraceae bacterium JC7].	26.32	418	255	11	40	426	230	625	2e-23	113
rs:WP_018234300	hypothetical protein [Thioalkalivibrio thiocyanodenitrificans].	38.92	185	100	3	255	439	13	184	2e-23	108
rs:WP_009138456	DNA topoisomerase [Slackia piriformis].	26.71	438	277	12	30	459	277	678	2e-23	113
rs:WP_022425806	DNA topoisomerase [Catenibacterium sp. CAG:290].	27.17	427	245	12	45	455	227	603	2e-23	113
rs:WP_015492626	Topoisomerase IA [Thermoplasmatales archaeon BRNA1].	25.91	440	266	17	34	458	233	627	2e-23	113
rs:WP_008656087	DNA topoisomerase I [Bacteroides sp. 3_1_33FAA].	26.36	368	232	9	60	425	209	539	2e-23	113
rs:WP_029441257	DNA topoisomerase I [Bacillus mojavensis].	25.82	426	259	15	50	457	227	613	2e-23	113
rs:WP_028597444	DNA topoisomerase I [Paenibacillus pasadenensis].	26.70	457	262	18	26	458	209	616	2e-23	113
rs:XP_007060121	PREDICTED: DNA topoisomerase 3-alpha [Chelonia mydas].	28.15	437	249	16	40	450	291	688	2e-23	113
rs:WP_044102077	DNA topoisomerase III, partial [Xanthomonas citri].	31.34	217	129	4	219	425	1	207	2e-23	107
tr:A0A0D6NPJ8_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.30	460	267	16	26	452	216	636	2e-23	113
rs:WP_044155905	DNA topoisomerase I [Salinibacillus aidingensis].	25.82	426	259	15	50	457	227	613	2e-23	113
tr:K7GGM4_PELSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.31	443	259	17	39	455	290	695	2e-23	113
rs:WP_027894204	DNA topoisomerase I [Meiothermus chliarophilus].	28.81	413	220	16	65	459	251	607	2e-23	113
rs:WP_035721465	DNA topoisomerase I [Gracilibacillus boraciitolerans].	25.41	429	264	12	47	457	225	615	2e-23	113
rs:WP_033608220	topoisomerase I, partial [Lactobacillus plantarum].	28.61	374	244	8	29	393	237	596	2e-23	112
rs:WP_044423532	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	37.87	169	96	2	284	452	3	162	2e-23	106
tr:T1I0Z0_RHOPR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.96	470	277	16	11	450	260	688	2e-23	113
rs:WP_044893781	DNA topoisomerase I [Bacillus alveayuensis].	25.40	433	252	17	50	457	227	613	3e-23	113
rs:WP_013897831	DNA topoisomerase [Methanosalsum zhilinae].	25.44	452	277	15	24	454	228	640	3e-23	113
tr:A7BSD2_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.78	410	228	15	65	452	265	632	3e-23	113
rs:WP_033874334	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	36.31	179	107	3	250	428	1	172	3e-23	106
rs:WP_008041237	topoisomerase I [Reinekea blandensis].	28.94	432	240	16	36	446	209	594	3e-23	113
rs:WP_009106276	DNA topoisomerase I [Desulfovibrio sp. U5L].	28.41	433	245	18	41	459	220	601	3e-23	112
tr:C2PZI4_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.01	446	266	16	34	457	180	583	3e-23	112
rs:WP_002088184	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	26.01	446	266	16	34	457	210	613	3e-23	112
rs:WP_033158878	DNA topoisomerase I [Methylomonas sp. LW13].	28.90	474	268	20	3	452	195	623	3e-23	113
rs:WP_021678245	DNA topoisomerase, partial [Porphyromonas gingivalis].	30.23	301	192	9	35	325	61	353	3e-23	109
tr:A0A0D6PWM0_KOMEU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.20	481	282	17	7	452	195	637	3e-23	113
tr:K7GGN4_PELSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.31	443	259	17	39	455	290	695	3e-23	113
tr:A0A017RZG0_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	25.00	464	271	18	22	454	18	435	3e-23	112
rs:WP_015413028	DNA topoisomerase I [Methanosarcina mazei].	25.24	424	267	14	40	454	247	629	3e-23	112
rs:WP_048040258	DNA topoisomerase I [Methanosarcina mazei].	25.24	424	267	14	40	454	247	629	3e-23	112
rs:WP_013718626	DNA topoisomerase I [Methanosaeta concilii].	25.89	448	277	15	18	454	213	616	3e-23	112
tr:U7RYE7_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.45	265	161	7	52	311	108	359	3e-23	109
tr:Q9HS90_HALSA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.40	438	263	16	30	454	71	466	3e-23	112
rs:XP_006126683	PREDICTED: DNA topoisomerase 3-alpha [Pelodiscus sinensis].	27.31	443	259	17	39	455	290	695	3e-23	113
rs:WP_006638185	DNA topoisomerase I [Bacillus sonorensis].	25.53	427	259	15	50	457	227	613	3e-23	112
rs:WP_026605122	DNA topoisomerase [Methylobacterium sp. 285MFTsu5.1].	28.57	427	270	14	40	439	236	654	3e-23	112
rs:WP_013390513	MULTISPECIES: DNA topoisomerase I [Bacillus subtilis group].	25.24	424	264	13	50	457	227	613	3e-23	112
rs:WP_010788600	DNA topoisomerase I [Bacillus atrophaeus].	25.24	424	264	13	50	457	227	613	4e-23	112
rs:WP_048046442	DNA topoisomerase I [Methanosarcina mazei].	25.24	424	267	14	40	454	247	629	4e-23	112
sp:TOP1P_XYLFA	RecName: Full=DNA topoisomerase I, plasmid {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	27.21	408	240	17	63	459	238	599	4e-23	112
tr:M5JHB5_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.68	173	100	2	36	201	230	396	4e-23	110
rs:WP_048047129	DNA topoisomerase I, partial [Methanosarcina mazei].	25.29	435	253	16	40	454	247	629	4e-23	112
tr:A0A090VXE1_9FLAO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL68623.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL68623.1};	29.21	291	177	9	179	454	2	278	4e-23	110
rs:WP_012966107	DNA topoisomerase I [Ferroglobus placidus].	26.50	400	248	13	59	454	250	607	4e-23	112
rs:WP_023908201	DNA topoisomerase I [Xylella fastidiosa].	27.21	408	240	17	63	459	238	599	4e-23	112
rs:WP_037281219	DNA topoisomerase I [Rubellimicrobium mesophilum].	28.11	434	254	15	47	454	231	632	4e-23	112
rs:WP_010902213	DNA topoisomerase I [Halobacterium salinarum].	28.42	380	221	13	86	454	293	632	4e-23	112
rs:WP_010508168	DNA topoisomerase I [Komagataeibacter europaeus].	26.20	481	282	17	7	452	195	637	4e-23	112
rs:WP_007046111	DNA topoisomerase [Subdoligranulum variabile].	28.17	252	174	4	47	296	235	481	4e-23	111
rs:WP_044593298	hypothetical protein [Cronobacter sakazakii].	41.84	141	80	2	245	385	7	145	4e-23	105
tr:L3QGS2_ECOLX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELE59473.1};	46.02	113	61	0	277	389	7	119	4e-23	104
rs:WP_023845950	DNA topoisomerase I, archaeal [Methanolobus tindarius].	26.42	424	264	13	40	454	243	627	4e-23	112
rs:WP_048040402	DNA topoisomerase I [Methanosarcina mazei].	25.24	424	267	14	40	454	247	629	4e-23	112
rs:WP_012106401	DNA topoisomerase I [Methanoregula boonei].	25.59	422	264	15	37	449	238	618	4e-23	112
rs:WP_021954365	DNA topoisomerase [Clostridium sp. CAG:921].	22.95	427	282	8	34	454	211	596	4e-23	112
rs:WP_003328956	DNA topoisomerase I [Bacillus atrophaeus].	25.24	424	264	13	50	457	227	613	4e-23	112
tr:T0MDS8_9SPHI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EQB80794.1};	29.89	271	174	6	153	421	5	261	4e-23	109
rs:WP_035720077	DNA topoisomerase I [Francisella sp. W12-1067].	27.07	399	244	13	70	452	256	623	4e-23	112
rs:WP_048126961	DNA topoisomerase I [Methanosarcina lacustris].	25.24	424	267	13	40	454	247	629	5e-23	112
rs:WP_048136116	MULTISPECIES: DNA topoisomerase I [Methanosarcina].	26.32	380	228	13	86	454	291	629	5e-23	112
rs:WP_012509456	DNA topoisomerase I [Pelodictyon phaeoclathratiforme].	27.56	439	240	16	47	451	235	629	5e-23	112
rs:WP_008957431	DNA topoisomerase III [Halomonas sp. HAL1].	28.69	366	217	13	62	399	292	641	5e-23	112
rs:WP_027963176	DNA topoisomerase I [Halalkalibacillus halophilus].	26.68	431	255	13	47	457	224	613	5e-23	112
rs:WP_022524170	DNA topoisomerase III [Halomonas sp. A3H3].	29.27	369	199	14	65	396	295	638	5e-23	112
rs:WP_024121390	DNA topoisomerase I [Bacillus mojavensis].	25.82	426	259	15	50	457	227	613	5e-23	112
rs:WP_010891446	hypothetical protein [Bacillus anthracis].	28.46	267	176	8	193	454	3	259	5e-23	107
tr:F7KHC2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.92	262	163	8	34	286	221	473	5e-23	110
rs:WP_018922566	DNA topoisomerase I [Salsuginibacillus kocurii].	26.04	434	254	14	47	457	224	613	5e-23	112
tr:A0A0C6FJ59_9RHIZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.34	392	246	14	40	405	255	641	6e-23	112
rs:WP_025800019	DNA topoisomerase I [Prevotella saccharolytica].	24.77	440	272	11	30	434	232	647	6e-23	112
rs:WP_008645707	hypothetical protein, partial [Bacteroides sp. 1_1_30].	33.59	259	159	9	31	286	233	481	6e-23	110
rs:WP_044983936	DNA topoisomerase III, partial [Lachnospiraceae bacterium 3_1_57FAA_CT1].	30.92	262	163	8	34	286	221	473	6e-23	110
rs:WP_043949226	DNA topoisomerase I [Candidatus Phaeomarinobacter ectocarpi].	27.62	449	253	14	41	454	226	637	6e-23	112
rs:WP_044546247	DNA topoisomerase I, partial [Parabacteroides distasonis].	27.41	343	233	9	18	350	217	553	6e-23	111
tr:X5MHV7_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.62	449	253	14	41	454	199	610	6e-23	112
rs:WP_002322645	DNA topoisomerase III, partial [Enterococcus faecium].	33.00	200	122	4	169	365	1	191	6e-23	108
rs:WP_020159280	DNA topoisomerase I [Methylobacter marinus].	28.41	447	248	19	32	452	222	622	7e-23	112
rs:WP_008084733	DNA topoisomerase I [Aciduliprofundum boonei].	26.58	365	225	11	61	421	261	586	7e-23	111
tr:J5UYF0_ENTFC	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EJX43737.1}; Flags: Fragment;	34.44	180	109	3	156	332	28	201	7e-23	105
tr:A0A090T6U4_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	51.46	103	49	1	93	195	2	103	7e-23	102
rs:WP_036248415	DNA topoisomerase I [Methylobacter sp. BBA5.1].	28.41	447	248	19	32	452	222	622	7e-23	111
rs:WP_038684634	hypothetical protein, partial [Rubrobacter radiotolerans].	28.04	428	254	14	39	454	243	628	7e-23	111
tr:U2CVW3_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ERI94679.1};	34.83	201	113	5	205	397	13	203	8e-23	108
rs:WP_001286967	DNA topoisomerase I [Bacillus cereus].	24.64	483	299	16	1	457	170	613	8e-23	111
rs:WP_042855966	hypothetical protein [Escherichia coli].	36.88	160	101	0	36	195	51	210	8e-23	105
rs:WP_020087305	DNA topoisomerase I [Hyphomicrobium zavarzinii].	28.32	452	254	17	43	452	227	650	8e-23	112
rs:WP_009812653	DNA topoisomerase I [Roseovarius nubinhibens].	29.03	434	245	16	47	454	231	627	8e-23	111
rs:WP_048171972	DNA topoisomerase I [Methanosarcina sp. 2.H.A.1B.4].	26.32	380	228	13	86	454	291	629	8e-23	111
tr:A0A023X4A7_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.04	428	254	14	39	454	243	628	8e-23	111
rs:WP_022369374	DNA topoisomerase [Firmicutes bacterium CAG:882].	25.76	427	261	13	48	457	227	614	9e-23	111
rs:WP_020858636	DNA topoisomerase I [SAR86 cluster bacterium SAR86B].	25.17	429	270	10	41	458	250	638	9e-23	111
tr:V2BXS5_SALDE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	40.62	128	75	1	36	163	251	377	9e-23	109
tr:A0A0B0HVB4_9BACL	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:KHF32527.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KHF32527.1};	28.79	257	158	4	182	435	6	240	9e-23	108
rs:WP_001719627	DNA topoisomerase III, partial [Salmonella enterica].	30.95	210	133	3	243	443	1	207	9e-23	107
rs:WP_008981066	DNA topoisomerase I [Ruminococcaceae bacterium D16].	27.40	427	253	13	47	454	228	616	9e-23	111
rs:WP_031915413	DNA topoisomerase III, partial [Staphylococcus aureus].	29.30	256	160	7	197	450	3	239	9e-23	107
rs:WP_040087766	DNA topoisomerase [Lactococcus garvieae].	28.23	379	225	13	30	398	231	572	9e-23	110
rs:WP_020434731	DNA topoisomerase [Clostridium sp. CAG:1000].	28.07	424	237	14	47	450	221	596	9e-23	111
rs:WP_015017538	DNA topoisomerase IA [Candidatus Nitrososphaera gargensis].	27.78	432	253	17	45	454	245	639	9e-23	111
tr:D9ZB73_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	27.78	432	253	17	45	454	245	639	1e-22	111
rs:WP_005039100	DNA topoisomerase I [Halococcus salifodinae].	25.45	440	277	15	28	454	230	631	1e-22	111
rs:WP_044960689	DNA topoisomerase III, partial [Blautia sp. KLE 1732].	34.83	201	113	5	205	397	30	220	1e-22	108
rs:WP_006076577	DNA topoisomerase I [Halococcus saccharolyticus].	25.64	433	274	14	31	454	238	631	1e-22	111
tr:W8A717_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.30	256	165	7	44	295	254	497	1e-22	110
rs:WP_045671983	DNA topoisomerase I [Paenibacillus beijingensis].	25.87	433	257	14	47	457	224	614	1e-22	111
tr:C2VXP8_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.64	483	299	16	1	457	140	583	1e-22	111
rs:WP_008354502	DNA topoisomerase I [Bacillus xiamenensis].	25.64	433	251	15	50	457	227	613	1e-22	111
rs:WP_048309806	DNA topoisomerase I [Anaerobacillus macyae].	25.93	428	262	14	47	457	224	613	1e-22	111
rs:WP_029269775	DNA topoisomerase I [Virgibacillus alimentarius].	25.05	471	280	18	18	457	187	615	1e-22	110
rs:WP_001286965	DNA topoisomerase I [Bacillus cereus].	24.43	483	300	16	1	457	170	613	1e-22	110
rs:WP_029007075	DNA topoisomerase I [Azospirillum halopraeferens].	28.02	464	265	17	26	454	213	642	1e-22	111
rs:WP_042232965	DNA topoisomerase I [Paenibacillus chitinolyticus].	24.42	471	282	15	18	457	187	614	1e-22	110
rs:WP_019090899	DNA topoisomerase I [Komagataeibacter europaeus].	25.99	481	283	17	7	452	195	637	1e-22	111
rs:WP_046475920	DNA topoisomerase I [Filomicrobium sp. W].	27.49	451	258	16	43	452	228	650	1e-22	111
rs:WP_012861272	DNA topoisomerase I [Sebaldella termitidis].	27.19	423	246	11	40	435	214	601	1e-22	110
rs:WP_048143884	DNA topoisomerase I, partial [Methanosarcina sp. 2.H.T.1A.15].	26.05	380	229	13	86	454	204	542	1e-22	110
rs:WP_010666274	DNA topoisomerase I [Acetobacter aceti].	26.00	427	252	13	59	452	241	636	1e-22	111
rs:WP_014868235	DNA topoisomerase I [Methanoculleus bourgensis].	25.00	448	276	17	18	450	216	618	1e-22	111
rs:WP_046414027	DNA topoisomerase I [Ruminococcus sp. A254.MGS-254].	26.28	430	253	17	47	452	228	617	1e-22	110
rs:WP_044343070	DNA topoisomerase I [Pseudomonas oryzihabitans].	27.32	410	242	14	60	459	234	597	1e-22	110
rs:WP_022798377	DNA topoisomerase I [Thermus islandicus].	27.63	438	245	15	36	454	232	616	1e-22	110
rs:WP_048141013	MULTISPECIES: DNA topoisomerase I [Methanosarcina].	26.05	380	229	13	86	454	291	629	2e-22	110
rs:WP_002305038	type I topoisomerase, partial [Enterococcus faecium].	29.34	242	160	4	156	392	22	257	2e-22	108
rs:WP_019084977	DNA topoisomerase I [Komagataeibacter europaeus].	25.99	481	283	17	7	452	195	637	2e-22	110
rs:WP_002467740	DNA topoisomerase III [Staphylococcus epidermidis].	28.67	286	186	6	34	314	226	498	2e-22	109
rs:WP_027160116	DNA topoisomerase I [Methylobacter luteus].	28.35	448	247	20	32	452	222	622	2e-22	110
rs:WP_033646015	DNA topoisomerase I [Bacillus anthracis].	24.43	483	300	16	1	457	170	613	2e-22	110
rs:WP_017753743	DNA topoisomerase I [Bacillus sp. ZYK].	26.95	423	248	14	50	452	227	608	2e-22	110
rs:WP_018302176	DNA topoisomerase I [Wenxinia marina].	28.70	439	252	18	41	454	225	627	2e-22	110
rs:WP_022684221	DNA topoisomerase I [Sphingobium sp. YL23].	28.83	437	249	17	40	452	219	617	2e-22	110
rs:WP_027954195	DNA topoisomerase I [Halobacillus kuroshimensis].	24.53	428	268	11	47	457	224	613	2e-22	110
rs:WP_036816340	DNA topoisomerase I [Pontibacillus yanchengensis].	24.15	468	287	15	18	457	187	614	2e-22	110
rs:WP_045367392	DNA topoisomerase I [Methyloceanibacter caenitepidi].	28.44	450	240	17	43	452	226	633	2e-22	110
rs:WP_015863435	DNA topoisomerase I [Geobacillus sp. WCH70].	26.56	433	249	17	49	457	226	613	2e-22	110
rs:WP_004215386	DNA topoisomerase I [Natrialba magadii].	24.88	434	277	14	31	454	255	649	2e-22	110
rs:WP_025902260	DNA topoisomerase I, partial [Tatumella sp. UCD-D_suzukii].	25.37	406	250	11	60	459	86	444	2e-22	109
rs:WP_020482931	DNA topoisomerase I [Methylomonas sp. MK1].	29.70	431	238	18	46	452	234	623	2e-22	110
rs:WP_010193401	DNA topoisomerase I [Bacillus sp. m3-13].	25.23	436	267	14	41	457	219	614	2e-22	110
rs:WP_013820830	DNA topoisomerase I [Methylomonas methanica].	29.14	429	243	18	46	452	234	623	2e-22	110
rs:WP_018661545	DNA topoisomerase I [Thermobrachium celere].	25.22	464	278	14	18	454	187	608	2e-22	110
rs:WP_022050564	DNA topoisomerase [Ruminococcus sp. CAG:254].	26.05	430	254	17	47	452	228	617	2e-22	110
rs:WP_034569661	DNA topoisomerase I [Carnobacterium divergens].	25.75	431	261	15	41	452	219	609	2e-22	110
rs:WP_021973169	DNA topoisomerase [Eubacterium sp. CAG:180].	27.50	440	241	18	48	454	226	620	2e-22	110
rs:WP_021962295	DNA topoisomerase [Mycoplasma sp. CAG:877].	25.11	470	284	14	1	449	172	594	2e-22	110
rs:WP_007695272	DNA topoisomerase I [Halococcus hamelinensis].	24.17	422	277	11	40	454	246	631	2e-22	110
rs:WP_040389618	DNA topoisomerase I [Catenibacterium mitsuokai].	27.17	427	245	12	45	455	227	603	2e-22	110
rs:WP_044746154	DNA topoisomerase I [Anoxybacillus sp. ATCC BAA-2555].	26.62	432	248	18	50	457	227	613	2e-22	110
gpu:CP009498_962	DNA topoisomerase 1 [Candidatus Endomicrobium sp. Rsa215]	26.37	474	245	18	45	453	228	662	2e-22	110
rs:WP_028273113	DNA topoisomerase I [Atopococcus tabaci].	25.35	426	259	15	46	452	225	610	2e-22	110
rs:WP_035020929	DNA topoisomerase I [Anoxybacillus flavithermus].	25.93	428	246	17	50	452	227	608	2e-22	110
rs:WP_042744581	topoisomerase I, partial [Oenococcus oeni].	31.36	220	137	6	66	282	278	486	2e-22	108
rs:WP_029775883	DNA topoisomerase I, partial [delta proteobacterium JGI 0000059-K16].	26.46	427	253	16	47	452	235	621	2e-22	110
rs:WP_012553896	DNA topoisomerase I [Gluconacetobacter diazotrophicus].	28.02	414	238	15	70	452	254	638	2e-22	110
rs:WP_029775121	DNA topoisomerase I, partial [delta proteobacterium JGI 0000059-J07].	26.46	427	253	16	47	452	220	606	2e-22	110
rs:WP_015052691	DNA topoisomerase [Methanolobus psychrophilus].	24.78	460	279	16	22	454	223	642	2e-22	110
rs:WP_013275886	DNA topoisomerase I [Thermosediminibacter oceani].	27.35	446	267	14	32	457	207	615	2e-22	110
rs:WP_033474582	DNA topoisomerase I [Bordetella bronchiseptica].	27.02	433	259	15	36	459	213	597	2e-22	110
tr:A0A0E0W3G8_BACAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.43	483	300	16	1	457	129	572	2e-22	110
rs:WP_048041984	DNA topoisomerase I [Methanosarcina mazei].	24.83	435	255	16	40	454	247	629	2e-22	110
tr:A0A0B3AFU7_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.73	457	273	16	22	454	222	631	2e-22	110
tr:R4FEZ4_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.93	428	246	17	50	452	228	609	2e-22	110
rs:WP_035574515	DNA topoisomerase I, partial [Elioraea tepidiphila].	27.63	427	238	14	61	452	244	634	3e-22	110
tr:E2NPJ5_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.17	427	245	12	45	455	233	609	3e-22	110
rs:WP_022365994	DNA topoisomerase [Firmicutes bacterium CAG:341].	23.64	461	258	14	47	449	225	649	3e-22	110
rs:WP_021429755	DNA topoisomerase I [[Clostridium] bifermentans].	23.46	439	267	13	35	454	220	608	3e-22	110
rs:WP_048447731	DNA topoisomerase [Methylobacterium variabile].	29.35	368	234	11	40	384	236	600	3e-22	110
rs:WP_047981281	DNA topoisomerase I [Ornithinibacillus contaminans].	25.59	469	279	17	18	457	187	614	3e-22	110
rs:YP_029935	DNA topoisomerase I [Bacillus anthracis str. Sterne].	24.43	483	300	16	1	457	170	613	3e-22	110
rs:WP_036292883	DNA topoisomerase I [Methylobacter whittenburyi].	28.19	447	249	19	32	452	222	622	3e-22	110
sp:TOP1_BACHD	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	26.27	434	253	18	47	457	224	613	3e-22	109
rs:WP_013301081	DNA topoisomerase I [Parvularcula bermudensis].	27.16	464	253	17	24	454	222	633	3e-22	110
tr:G8N977_9DEIN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.44	441	245	15	36	454	217	604	3e-22	110
tr:W6N420_CLOTY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000313|EMBL:CDL91243.1};	24.82	411	266	12	47	444	102	482	3e-22	109
rs:WP_037499141	DNA topoisomerase I [Sphingobacterium sp. ACCC 05744].	26.51	381	247	10	65	427	265	630	3e-22	109
rs:WP_012222293	DNA topoisomerase I [Gluconacetobacter diazotrophicus].	28.02	414	238	15	70	452	254	638	3e-22	110
tr:G9YLU1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.11	249	172	4	40	286	231	474	3e-22	108
tr:L1MQG7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	25.52	435	261	12	41	457	19	408	3e-22	108
rs:WP_002353995	DNA topoisomerase, partial [Enterococcus faecium].	31.78	236	149	5	57	289	35	261	3e-22	105
rs:WP_045836775	DNA topoisomerase I [Hyphomicrobium sp. 99].	27.15	453	256	14	43	452	227	648	3e-22	110
rs:WP_013841888	DNA topoisomerase I [Desulfotomaculum ruminis].	25.06	435	259	16	46	457	224	614	3e-22	109
rs:WP_032444896	DNA topoisomerase III, partial [Klebsiella pneumoniae].	29.03	279	170	7	197	459	5	271	3e-22	107
rs:WP_048038343	DNA topoisomerase I [Methanosarcina mazei].	25.00	424	268	14	40	454	247	629	3e-22	109
rs:WP_041433679	DNA topoisomerase I [Thermus sp. CCB_US3_UF1].	27.44	441	245	15	36	454	218	605	3e-22	110
rs:WP_043964776	DNA topoisomerase I [Anoxybacillus thermarum].	24.33	485	288	18	1	452	170	608	3e-22	109
rs:WP_011909276	DNA topoisomerase I [Rhodobacter sphaeroides].	28.11	434	251	15	47	454	229	627	3e-22	110
rs:WP_037457389	DNA topoisomerase I [Sphingobium chlorophenolicum].	28.64	440	246	17	40	452	219	617	3e-22	110
rs:WP_039996512	DNA topoisomerase III, partial [Flavonifractor plautii].	28.11	249	172	4	40	286	228	471	3e-22	108
rs:WP_004407605	DNA topoisomerase III, partial [Pseudomonas syringae].	44.76	105	58	0	67	171	273	377	3e-22	107
rs:WP_021433769	DNA topoisomerase I [[Clostridium] bifermentans].	23.46	439	267	13	35	454	220	608	3e-22	109
rs:WP_014549399	DNA topoisomerase I [Francisella tularensis].	28.15	405	242	14	67	454	252	624	3e-22	109
rs:WP_001286968	DNA topoisomerase I [Bacillus thuringiensis].	24.22	483	301	16	1	457	170	613	3e-22	109
tr:C3F5U4_BACTU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.43	483	300	16	1	457	163	606	3e-22	109
rs:WP_032734728	DNA topoisomerase I [Klebsiella oxytoca].	27.02	433	259	15	36	459	213	597	3e-22	109
rs:WP_040008887	DNA topoisomerase I [Francisella sp. FSC1006].	28.54	403	240	13	66	452	252	622	3e-22	109
rs:WP_003035615	DNA topoisomerase I [Francisella tularensis].	28.15	405	242	14	67	454	252	624	3e-22	109
rs:WP_022042897	DNA topoisomerase III [Bacteroides caccae CAG:21].	29.63	270	173	5	159	427	1	254	3e-22	106
rs:WP_044462178	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	27.67	412	251	14	42	446	256	627	4e-22	109
rs:WP_042958252	DNA topoisomerase, partial [Enterococcus faecium].	34.24	184	112	3	182	365	14	188	4e-22	106
rs:WP_022337852	DNA topoisomerase [Clostridium sp. CAG:433].	26.13	444	239	15	65	456	241	647	4e-22	109
rs:WP_025064897	DNA topoisomerase, partial [Prevotella disiens].	27.99	318	205	8	112	426	1	297	4e-22	107
rs:WP_035065874	DNA topoisomerase I [Anoxybacillus gonensis].	24.33	485	288	18	1	452	170	608	4e-22	109
rs:WP_025064910	DNA topoisomerase, partial [Prevotella disiens].	31.27	275	174	6	112	384	1	262	4e-22	107
rs:WP_031861022	DNA topoisomerase III, partial [Staphylococcus aureus].	26.94	297	196	6	35	330	219	495	4e-22	108
rs:WP_019595578	DNA topoisomerase I [Peptostreptococcus anaerobius].	25.52	435	261	12	41	457	219	608	4e-22	109
rs:WP_009674480	MULTISPECIES: DNA topoisomerase I [Paenibacillus].	24.42	471	282	15	18	457	187	614	4e-22	109
rs:WP_031431468	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	35.90	156	100	0	35	190	35	190	4e-22	103
rs:WP_033644711	DNA topoisomerase, partial [Enterococcus faecium].	34.24	184	112	3	182	365	13	187	4e-22	106
rs:WP_009647413	DNA topoisomerase I [Actinomyces sp. ICM47].	28.69	366	213	12	42	385	253	592	4e-22	109
rs:WP_002564088	MULTISPECIES: DNA topoisomerase I [Atopobium].	25.92	436	273	12	33	454	275	674	4e-22	109
rs:WP_013180152	DNA topoisomerase I [Methanococcus voltae].	26.65	439	249	14	40	454	245	634	4e-22	109
rs:WP_048051259	DNA topoisomerase I [Methanosarcina soligelidi].	24.83	435	255	16	40	454	247	629	4e-22	109
rs:WP_044346183	DNA topoisomerase I [Desulfarculus sp. SPR].	28.47	425	250	13	47	452	225	614	4e-22	109
rs:WP_002844064	DNA topoisomerase I [Peptostreptococcus anaerobius].	25.52	435	261	12	41	457	219	608	4e-22	109
rs:WP_047376136	DNA topoisomerase I [Bacillus anthracis].	24.38	480	298	16	1	454	170	610	4e-22	109
rs:WP_008092043	DNA topoisomerase I [Haloferax prahovense].	24.55	444	263	15	35	454	245	640	4e-22	109
tr:W0RPS3_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.33	450	255	17	41	458	276	685	4e-22	109
rs:WP_004972896	DNA topoisomerase I [Haloferax gibbonsii].	24.55	444	263	15	35	454	245	640	4e-22	109
rs:WP_034559735	DNA topoisomerase I [Carnobacterium gallinarum].	25.99	431	260	15	41	452	219	609	4e-22	109
rs:WP_006169072	DNA topoisomerase I [Natrialba chahannaoensis].	24.88	434	277	14	31	454	238	632	4e-22	109
rs:WP_035290647	DNA topoisomerase I [Clostridium sp. KNHs214].	24.49	445	259	14	40	457	217	611	4e-22	109
rs:WP_026300384	DNA topoisomerase I [Halomonas lutea].	28.26	414	244	15	51	452	270	642	4e-22	109
rs:WP_035481733	hypothetical protein [Burkholderia phenoliruptrix].	37.38	206	110	6	263	452	6	208	4e-22	103
rs:WP_014714499	DNA topoisomerase I [Francisella noatunensis].	28.82	406	234	15	67	452	252	622	4e-22	109
rs:WP_008321710	DNA topoisomerase I [Haloferax mucosum].	24.55	444	266	13	31	454	246	640	4e-22	109
rs:WP_010052918	DNA topoisomerase I [Carnobacterium maltaromaticum].	26.03	438	266	16	34	452	211	609	5e-22	109
rs:WP_009732875	DNA topoisomerase I [Anoxybacillus sp. DT3-1].	24.54	485	287	19	1	452	170	608	5e-22	109
rs:WP_024396453	DNA topoisomerase [Streptococcus suis].	27.97	354	211	12	56	401	258	575	5e-22	108
rs:WP_010334238	DNA topoisomerase I [Bacillus mojavensis].	25.59	426	260	15	50	457	227	613	5e-22	109
rs:WP_021659817	DNA topoisomerase I [Clostridium sp. ATCC 29733].	27.02	433	252	12	43	452	221	612	5e-22	109
rs:WP_012283267	DNA topoisomerase I [Heliobacterium modesticaldum].	25.23	428	263	11	48	457	226	614	5e-22	109
rs:WP_021296476	DNA topoisomerase I [Alicyclobacillus acidoterrestris].	26.96	434	257	13	41	454	218	611	5e-22	108
rs:WP_034550064	DNA topoisomerase I [Carnobacterium funditum].	24.83	435	260	17	41	452	219	609	5e-22	108
rs:WP_012521875	DNA topoisomerase I [Phenylobacterium zucineum].	28.79	448	246	18	41	454	223	631	5e-22	109
rs:WP_029727426	MULTISPECIES: DNA topoisomerase I [Sphingomonas].	26.63	492	287	15	1	452	171	628	5e-22	109
rs:WP_011034974	DNA topoisomerase I [Methanosarcina mazei].	24.76	424	269	14	40	454	247	629	5e-22	108
rs:WP_027307457	DNA topoisomerase I [Caloramator sp. ALD01].	25.41	429	259	13	47	456	224	610	5e-22	108
tr:U2DY69_9BACE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERI84806.1};	30.89	246	158	5	154	398	30	264	6e-22	106
rs:WP_044071284	hypothetical protein, partial [Prevotella timonensis].	31.39	274	173	6	113	384	1	261	6e-22	106
rs:WP_014547714	DNA topoisomerase I [Francisella tularensis].	28.15	405	242	14	67	454	252	624	6e-22	108
rs:WP_019692747	topoisomerase I [Pseudomonas fluorescens].	27.91	412	250	14	42	446	256	627	6e-22	109
rs:WP_013380804	DNA topoisomerase I [Eubacterium limosum].	26.89	424	250	13	50	454	229	611	6e-22	108
rs:WP_029724461	DNA topoisomerase I [Sphingomonas sp. JGI 0001003-D23].	26.63	492	287	15	1	452	171	628	6e-22	108
rs:WP_026294208	DNA topoisomerase I [Saccharibacter floricola].	25.81	430	261	12	53	454	237	636	6e-22	108
rs:WP_010719185	DNA topoisomerase III [Enterococcus hirae].	27.90	276	185	4	167	437	319	585	6e-22	108
rs:WP_013846732	DNA topoisomerase I [Sphingobium chlorophenolicum].	28.60	437	250	17	40	452	219	617	6e-22	108
rs:WP_035115298	DNA topoisomerase I [Clostridium sp. NCR].	23.46	439	267	13	35	454	220	608	6e-22	108
rs:WP_021273797	DNA topoisomerase I [Bacteriovorax sp. Seq25_V].	25.57	438	271	14	41	453	284	691	6e-22	108
rs:WP_009368920	DNA topoisomerase I [Bilophila sp. 4_1_30].	24.71	437	278	16	36	459	208	606	6e-22	108
rs:WP_045645036	DNA topoisomerase I, partial [Peptococcaceae bacterium BRH_c4b].	26.22	450	261	16	30	457	214	614	6e-22	108
rs:WP_020221956	DNA topoisomerase I [Halarchaeum acidiphilum].	25.87	402	255	12	60	454	267	632	6e-22	108
rs:WP_008245900	DNA topoisomerase I [Sulfurovum sp. AR].	28.15	444	248	17	31	452	209	603	6e-22	108
rs:WP_022695662	DNA topoisomerase I [Ponticaulis koreensis].	27.54	443	250	14	41	452	224	626	6e-22	108
rs:WP_025746457	DNA topoisomerase I [Caldicoprobacter oshimai].	26.34	429	253	17	49	454	227	615	6e-22	108
rs:WP_027448276	DNA topoisomerase I [Pontibacillus marinus].	26.05	430	260	14	47	457	224	614	6e-22	108
rs:WP_042415599	DNA topoisomerase I [Geomicrobium sp. JCM 19038].	25.94	424	253	15	49	452	231	613	6e-22	108
tr:J8F712_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.70	266	168	9	35	293	247	500	6e-22	108
tr:K8ECN4_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.86	437	249	16	48	457	226	614	7e-22	108
rs:WP_021935290	DNA topoisomerase [Peptostreptococcus anaerobius CAG:621].	25.52	435	261	12	41	457	219	608	7e-22	108
rs:WP_005224424	DNA topoisomerase I [Marichromatium purpuratum].	26.75	415	243	14	60	452	245	620	7e-22	108
rs:WP_047209919	DNA topoisomerase [Streptococcus agalactiae].	27.68	354	212	11	56	401	258	575	7e-22	108
rs:WP_038351417	DNA topoisomerase I [Eubacterium limosum].	26.68	431	256	13	43	454	222	611	7e-22	108
rs:WP_004077426	DNA topoisomerase I [Methanoplanus limicola].	24.89	450	272	18	18	449	216	617	7e-22	108
rs:WP_047398693	DNA topoisomerase I [Bacillus anthracis].	24.22	483	301	16	1	457	170	613	7e-22	108
rs:WP_044976667	hypothetical protein [Ruminococcus sp. HUN007].	25.75	431	265	14	45	450	255	655	7e-22	108
rs:WP_026675886	DNA topoisomerase I [Fictibacillus gelatini].	24.33	485	299	18	1	457	170	614	7e-22	108
rs:WP_046526653	DNA topoisomerase I [Bacillus sp. L_1B0_12].	25.40	433	252	15	50	457	227	613	7e-22	108
rs:WP_035440335	DNA topoisomerase I, partial [Asaia sp. SF2.1].	25.94	424	249	15	61	452	8	398	7e-22	107
rs:WP_007921310	topoisomerase I [Pseudomonas sp. GM17].	27.43	412	252	14	42	446	256	627	7e-22	108
rs:WP_000210271	MULTISPECIES: DNA topoisomerase I [Gammaproteobacteria].	26.37	455	266	18	19	459	198	597	7e-22	108
rs:WP_042407113	DNA topoisomerase I [Geobacillus caldoxylosilyticus].	25.06	447	269	15	34	457	210	613	7e-22	108
rs:WP_011022481	DNA topoisomerase I [Methanosarcina acetivorans].	24.53	424	270	13	40	454	247	629	7e-22	108
rs:WP_018780929	MULTISPECIES: DNA topoisomerase I [Bacillus].	25.28	439	265	15	40	457	217	613	7e-22	108
rs:WP_036124760	DNA topoisomerase I [Lysinibacillus sphaericus].	24.38	480	295	16	1	452	170	609	7e-22	108
rs:WP_013810225	DNA topoisomerase I [Desulfotomaculum carboxydivorans].	25.35	434	255	14	48	457	231	619	8e-22	108
rs:WP_021873408	DNA topoisomerase [Firmicutes bacterium CAG:822].	28.17	426	232	17	46	450	225	597	8e-22	108
rs:WP_018257964	DNA topoisomerase I [Halomicrobium katesii].	24.95	461	272	17	22	454	216	630	8e-22	108
rs:WP_038580619	DNA topoisomerase I [Pseudomonas chlororaphis].	27.43	412	252	14	42	446	256	627	8e-22	108
rs:WP_028682992	DNA topoisomerase I [Pseudomonas chlororaphis].	27.43	412	252	14	42	446	256	627	8e-22	108
rs:WP_036683311	DNA topoisomerase I, partial [Pelobacter seleniigenes].	26.32	437	257	14	41	454	226	620	8e-22	108
rs:WP_036893583	hypothetical protein, partial [Prevotella timonensis].	31.39	274	173	6	113	384	1	261	8e-22	105
rs:WP_009042977	topoisomerase I [Pseudomonas chlororaphis].	27.43	412	252	14	42	446	256	627	8e-22	108
rs:WP_017437098	DNA topoisomerase I [Geobacillus caldoxylosilyticus].	25.06	447	269	15	34	457	210	613	8e-22	108
tr:K4XDU0_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	36.88	160	101	0	36	195	190	349	8e-22	105
rs:WP_048239695	DNA topoisomerase I [Bacillus pumilus].	25.53	427	259	14	50	457	227	613	8e-22	108
tr:C3BNQ9_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.28	439	265	15	40	457	210	606	8e-22	108
rs:WP_013331964	topoisomerase I [Halomonas elongata].	28.71	425	240	17	51	458	272	650	8e-22	108
rs:WP_016704946	topoisomerase I [Pseudomonas chlororaphis].	27.43	412	252	14	42	446	256	627	8e-22	108
rs:WP_009047964	topoisomerase I [Pseudomonas chlororaphis].	27.43	412	252	14	42	446	256	627	8e-22	108
rs:WP_025804224	DNA topoisomerase I [Pseudomonas chlororaphis].	27.43	412	252	14	42	446	256	627	8e-22	108
rs:WP_007119147	DNA topoisomerase I [Oceanibulbus indolifex].	29.93	441	243	19	41	454	225	626	8e-22	108
rs:WP_043118135	DNA topoisomerase I [Solemya velum gill symbiont].	28.00	425	255	15	44	452	230	619	8e-22	108
tr:W0JX63_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.73	377	235	11	86	454	291	630	8e-22	108
rs:WP_023968539	topoisomerase I [Pseudomonas chlororaphis].	27.43	412	252	14	42	446	256	627	8e-22	108
rs:WP_007039086	DNA topoisomerase I [Thiorhodococcus drewsii].	27.85	413	245	13	59	452	242	620	8e-22	108
rs:WP_015763957	DNA topoisomerase I [Halomicrobium mukohataei].	25.33	458	274	18	22	454	216	630	9e-22	108
tr:X2H807_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.78	138	90	0	36	173	75	212	9e-22	103
rs:WP_004234233	DNA topoisomerase III [Streptococcus parauberis].	27.56	381	229	13	30	400	231	574	9e-22	108
rs:WP_021817184	topoisomerase I [Halomonas sp. BJGMM-B45].	29.15	398	221	16	77	458	296	648	9e-22	108
rs:WP_033444675	DNA topoisomerase I, partial [Candidatus Odyssella thessalonicensis].	25.23	440	261	14	47	454	231	634	9e-22	108
rs:WP_029498225	DNA topoisomerase I [Kurthia huakuii].	24.17	484	293	18	1	452	170	611	9e-22	108
rs:WP_013553114	DNA topoisomerase I [Nitratifractor salsuginis].	26.12	425	244	16	47	450	224	599	1e-21	108
rs:WP_031552912	DNA topoisomerase I [Oribacterium sp. FC2011].	25.46	432	272	12	34	454	213	605	1e-21	108
rs:WP_016131882	DNA topoisomerase 1 [Bacillus cereus].	25.28	439	265	15	40	457	217	613	1e-21	108
rs:WP_022948084	DNA topoisomerase I [Methylohalobius crimeensis].	28.47	432	244	18	44	452	232	621	1e-21	108
rs:WP_012583876	DNA topoisomerase I [Dictyoglomus turgidum].	26.11	406	237	16	69	454	247	609	1e-21	108
rs:WP_040228112	DNA topoisomerase I [Bhargavaea cecembensis].	26.54	471	270	21	18	457	187	612	1e-21	108
rs:WP_006011464	DNA topoisomerase I [Glaciecola pallidula].	26.62	417	252	13	42	446	256	630	1e-21	108
rs:WP_021863724	DNA topoisomerase [Clostridium sp. CAG:715].	25.27	459	279	14	18	450	200	620	1e-21	108
tr:D5DPQ9_BACMQ	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ADE68980.1};	36.75	166	95	3	221	385	7	163	1e-21	104
rs:WP_025056227	DNA topoisomerase I [Sulfitobacter noctilucicola].	28.86	440	249	20	41	454	225	626	1e-21	108
rs:WP_028558260	DNA topoisomerase I [Paenibacillus sp. URHA0014].	26.61	436	250	17	47	457	224	614	1e-21	108
tr:A0A061NCY7_9BACL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.94	424	253	15	49	452	224	606	1e-21	108
rs:WP_006654231	DNA topoisomerase I [Natrialba hulunbeirensis].	24.88	434	277	14	31	454	255	649	1e-21	108
rs:XP_001950527	PREDICTED: DNA topoisomerase 3-alpha [Acyrthosiphon pisum].	24.83	439	269	14	40	453	289	691	1e-21	108
rs:WP_017359093	DNA topoisomerase I [Bacillus pumilus].	25.06	427	261	14	50	457	227	613	1e-21	108
tr:M7BIP5_CHEMY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.57	399	221	15	77	450	216	575	1e-21	108
rs:WP_044456509	DNA topoisomerase, partial [Bacillus subtilis].	31.94	216	130	5	249	455	1	208	1e-21	103
rs:WP_044335050	DNA topoisomerase I [Sphingomonas sp. WHSC-8].	27.96	465	262	16	22	452	192	617	1e-21	108
rs:WP_044757939	DNA topoisomerase, partial [Streptococcus suis].	32.17	258	157	7	52	304	108	352	1e-21	105
rs:WP_040366499	DNA topoisomerase I [Enterococcus italicus].	25.39	453	260	17	34	457	211	614	1e-21	108
tr:A0A060HRZ8_9ARCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.07	447	248	15	40	454	250	650	1e-21	108
rs:WP_027414585	DNA topoisomerase I [Aneurinibacillus terranovensis].	24.44	495	276	17	18	449	187	646	1e-21	107
rs:WP_036123967	MULTISPECIES: DNA topoisomerase I [Lysinibacillus].	24.64	483	290	18	1	452	170	609	1e-21	107
rs:WP_016115962	MULTISPECIES: DNA topoisomerase 1 [Bacillus].	25.28	439	265	15	40	457	217	613	1e-21	107
tr:N0BDX9_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.37	453	255	14	43	452	257	678	1e-21	108
rs:WP_033611595	DNA topoisomerase, partial [Enterococcus faecium].	26.93	323	207	8	68	385	281	579	1e-21	107
rs:WP_046400761	DNA topoisomerase I [Francisella tularensis].	28.15	405	242	14	67	454	246	618	1e-21	108
rs:WP_008084369	DNA topoisomerase I [Aciduliprofundum boonei].	26.03	365	227	11	61	421	261	586	1e-21	108
rs:WP_024026822	DNA topoisomerase I [Bacillus vireti].	26.43	420	243	18	60	457	239	614	1e-21	107
rs:WP_010726543	DNA topoisomerase III [Enterococcus faecium].	26.93	323	207	8	68	385	281	579	1e-21	107
tr:C3APD2_BACMY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.28	439	265	15	40	457	210	606	1e-21	107
rs:WP_022493747	DNA topoisomerase [Clostridium sp. CAG:628].	26.16	432	223	14	75	450	247	638	1e-21	107
rs:WP_038065387	hypothetical protein, partial [Thermodesulfovibrio thiophilus].	27.04	429	257	13	41	452	232	621	1e-21	108
rs:WP_039423665	DNA topoisomerase I, partial [Porphyromonas gulae].	28.17	284	191	7	146	426	2	275	1e-21	103
rs:WP_025908998	DNA topoisomerase I [Bacillus flexus].	24.64	487	294	19	1	457	170	613	1e-21	107
rs:WP_033008161	MULTISPECIES: DNA topoisomerase I [Bacillaceae].	25.05	487	292	17	1	457	170	613	1e-21	107
rs:WP_033016014	DNA topoisomerase I [Geobacillus stearothermophilus].	25.05	487	292	17	1	457	170	613	1e-21	107
rs:WP_012429273	DNA topoisomerase I [Francisella tularensis].	28.15	405	242	14	67	454	252	624	1e-21	107
rs:WP_003038456	DNA topoisomerase I [Francisella tularensis].	28.15	405	242	14	67	454	252	624	1e-21	107
tr:E6LFJ8_9ENTE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.39	453	260	17	34	457	218	621	1e-21	107
sp:TOP1_AQUAE	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	31.12	347	179	13	47	377	214	516	1e-21	107
rs:WP_010858431	DNA topoisomerase I [Lysinibacillus sphaericus].	26.77	437	252	19	40	452	217	609	1e-21	107
rs:WP_035444428	DNA topoisomerase I [Asaia platycodi].	26.35	425	246	16	61	452	245	635	1e-21	108
rs:WP_046550239	DNA topoisomerase I [Sulfurovum lithotrophicum].	27.54	443	252	17	31	452	209	603	1e-21	107
rs:WP_016179974	MULTISPECIES: DNA topoisomerase 1 [Enterococcus].	24.26	441	280	12	34	457	211	614	1e-21	107
tr:M5RDN2_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.17	433	253	15	50	457	229	615	1e-21	107
rs:WP_028263348	DNA topoisomerase [Atopobium fossor].	26.55	403	233	12	69	454	318	674	1e-21	108
rs:WP_035700740	DNA topoisomerase I [Bacillus altitudinis].	25.17	433	253	15	50	457	227	613	1e-21	107
tr:A0A061P3Q6_9BACL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.00	426	245	19	50	452	197	579	1e-21	107
rs:WP_015280197	DNA topoisomerase I [Thioflavicoccus mobilis].	29.00	431	240	17	46	452	237	625	1e-21	107
rs:WP_031548586	DNA topoisomerase I [Salinicoccus luteus].	25.23	428	254	17	47	452	223	606	1e-21	107
rs:WP_034317776	DNA topoisomerase I [Bacillus sp. DW5-4].	25.17	433	253	15	50	457	227	613	1e-21	107
rs:WP_044895581	DNA topoisomerase I [Bacillus alveayuensis].	25.35	430	256	15	50	457	227	613	1e-21	107
rs:WP_029200664	DNA topoisomerase I [Oribacterium sp. NK2B42].	24.30	465	267	14	34	449	213	641	1e-21	107
rs:WP_003394922	DNA topoisomerase I [Anoxybacillus flavithermus].	24.12	485	289	19	1	452	170	608	1e-21	107
rs:WP_016133223	DNA topoisomerase 1 [Bacillus cereus].	25.28	439	265	15	40	457	217	613	1e-21	107
tr:K1RZ42_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC48414.1}; Flags: Fragment;	31.32	281	167	8	174	445	3	266	1e-21	104
rs:WP_017367241	MULTISPECIES: DNA topoisomerase I [Bacillus].	25.17	433	253	15	50	457	227	613	1e-21	107
rs:WP_043253486	DNA topoisomerase I [Pseudomonas knackmussii].	27.11	391	234	12	68	446	275	626	1e-21	107
rs:WP_027363825	DNA topoisomerase I [Desulfotomaculum alcoholivorax].	25.40	437	247	13	65	449	244	653	1e-21	107
rs:WP_003026515	DNA topoisomerase I [Francisella tularensis].	28.15	405	242	14	67	454	252	624	1e-21	107
rs:WP_018632196	hypothetical protein [Meganema perideroedes].	29.19	418	235	17	61	454	244	624	1e-21	107
rs:WP_019418404	DNA topoisomerase I [Anoxybacillus kamchatkensis].	24.12	485	289	18	1	452	170	608	1e-21	107
rs:WP_041321243	DNA topoisomerase I [Hyphomicrobium denitrificans].	27.81	453	253	15	43	452	227	648	1e-21	107
rs:WP_026674294	DNA topoisomerase I [Bacillus bogoriensis].	26.01	419	258	10	50	452	227	609	1e-21	107
rs:XP_003378698	DNA topoisomerase 3-alpha [Trichinella spiralis].	25.39	453	261	15	39	451	252	667	1e-21	107
rs:WP_003017863	DNA topoisomerase I [Francisella tularensis].	28.15	405	242	14	67	454	252	624	1e-21	107
rs:WP_040015752	DNA topoisomerase III, partial [Dorea formicigenerans].	28.96	259	172	6	34	286	224	476	2e-21	106
rs:WP_003041712	DNA topoisomerase I [Francisella tularensis].	28.15	405	242	14	67	454	252	624	2e-21	107
rs:WP_008323216	DNA topoisomerase I [Haloferax elongans].	25.18	413	242	13	61	454	276	640	2e-21	107
rs:WP_003033127	DNA topoisomerase I [Francisella tularensis].	28.15	405	242	14	67	454	252	624	2e-21	107
rs:WP_001235772	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	36.88	160	101	0	36	195	246	405	2e-21	105
rs:WP_032548942	DNA topoisomerase III, partial [Vibrio crassostreae].	41.54	130	76	0	275	404	6	135	2e-21	101
rs:WP_003014690	DNA topoisomerase I [Francisella tularensis].	28.15	405	242	14	67	454	252	624	2e-21	107
rs:WP_021094222	MULTISPECIES: DNA topoisomerase I [Anoxybacillus].	24.12	485	289	18	1	452	170	608	2e-21	107
rs:WP_007505175	DNA topoisomerase I [Caldalkalibacillus thermarum].	25.69	432	258	18	47	457	224	613	2e-21	107
rs:WP_008344821	MULTISPECIES: DNA topoisomerase I [Bacillus].	25.17	433	253	15	50	457	227	613	2e-21	107
rs:WP_018757832	DNA topoisomerase I [Paenibacillus terrigena].	26.23	446	253	14	41	457	218	616	2e-21	107
rs:WP_015283225	DNA topoisomerase I, archaeal [Aciduliprofundum sp. MAR08-339].	27.17	346	195	11	59	393	259	558	2e-21	107
rs:WP_034740925	DNA topoisomerase I [Bacillus wakoensis].	26.18	424	251	14	50	452	227	609	2e-21	107
rs:WP_035392076	MULTISPECIES: DNA topoisomerase I [Bacillus].	25.17	433	253	15	50	457	227	613	2e-21	107
tr:A0A0E4FFJ1_FRATT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:AKE20784.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AKE20784.1};	28.15	405	242	14	67	454	119	491	2e-21	107
rs:WP_017151250	DNA topoisomerase I [Bacillus sp. FJAT-13831].	25.28	439	265	15	40	457	217	613	2e-21	107
rs:WP_036173528	DNA topoisomerase I [Maribius sp. MOLA 401].	27.45	459	253	16	41	454	225	648	2e-21	107
tr:B0GA94_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.62	269	180	6	34	296	224	486	2e-21	106
rs:WP_038230195	DNA topoisomerase III [Xylella fastidiosa].	48.36	122	23	2	123	244	3	84	2e-21	98.6
rs:WP_047792750	DNA topoisomerase I [Peptococcaceae bacterium 1109].	26.07	422	253	13	54	456	231	612	2e-21	107
rs:WP_036869928	DNA topoisomerase I, partial [Prevotella disiens].	28.57	280	183	7	108	384	3	268	2e-21	105
tr:T0RV12_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.94	445	285	12	41	459	272	693	2e-21	107
rs:WP_012009947	DNA topoisomerase I [Bacillus pumilus].	24.82	427	262	14	50	457	227	613	2e-21	107
rs:WP_020504206	DNA topoisomerase I [Lamprocystis purpurea].	29.41	425	248	16	45	452	231	620	2e-21	107
rs:WP_034675695	DNA topoisomerase I [Bacillus niacini].	24.53	424	264	13	47	452	225	610	2e-21	107
rs:WP_034727506	hypothetical protein, partial [Bacteriovorax sp. BSW11_IV].	24.94	445	285	12	41	459	285	706	2e-21	107
rs:WP_023458044	DNA topoisomerase I [Asticcacaulis sp. AC466].	27.38	442	260	13	41	454	223	631	2e-21	107
tr:B7C9A6_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.30	273	179	6	35	296	217	486	2e-21	106
rs:WP_029314681	DNA topoisomerase I [Acidiphilium angustum].	27.34	428	238	16	60	452	244	633	2e-21	107
rs:XP_656880	DNA topoisomerase III [Entamoeba histolytica HM-1:IMSS].	25.99	377	226	13	39	399	256	595	2e-21	107
rs:WP_021044116	DNA topoisomerase I [halophilic archaeon J07HX64].	24.37	398	241	14	72	454	277	629	2e-21	107
rs:WP_027090882	DNA topoisomerase I [Cohnella thermotolerans].	25.73	443	267	15	36	457	213	614	2e-21	107
rs:WP_003105435	DNA topoisomerase [Streptococcus parauberis].	27.97	379	226	13	30	398	231	572	2e-21	107
rs:WP_046822586	DNA topoisomerase I [Clostridium sp. JC272].	23.23	439	268	13	35	454	220	608	2e-21	107
rs:WP_012159330	DNA topoisomerase I [Alkaliphilus oremlandii].	25.06	427	267	10	45	456	223	611	2e-21	107
rs:WP_023409680	DNA topoisomerase I [uncultured Thiohalocapsa sp. PB-PSB1].	26.45	431	251	17	46	452	240	628	2e-21	107
rs:WP_044993277	DNA topoisomerase I [Lachnospiraceae bacterium JC7].	25.58	430	274	12	34	454	213	605	2e-21	107
tr:K0FR22_BACTU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.84	483	298	17	1	457	140	583	2e-21	107
rs:WP_023846213	topoisomerase IA [Methanolobus tindarius].	23.85	457	280	12	24	454	228	642	2e-21	107
tr:A0A0D6Q8Q4_KOMXY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.14	482	281	18	7	452	195	637	2e-21	107
rs:WP_010751238	DNA topoisomerase 1 [Enterococcus villorum].	24.72	449	270	14	33	457	210	614	2e-21	107
rs:WP_036706889	DNA topoisomerase I [Paenibacillus sp. P1XP2].	25.87	429	256	15	50	457	227	614	2e-21	107
rs:WP_040466192	DNA topoisomerase III, partial [Holdemanella biformis].	29.66	263	171	6	35	286	217	476	2e-21	106
tr:A0A0E4CSD2_9STRE	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CQR24418.1}; Flags: Precursor;	24.31	436	269	12	34	452	231	622	2e-21	107
rs:WP_006036574	DNA topoisomerase I [Paenibacillus curdlanolyticus].	25.48	471	278	17	18	457	187	615	2e-21	107
rs:WP_027357341	DNA topoisomerase I [Desulfotomaculum thermocisternum].	26.03	438	249	17	47	457	225	614	2e-21	107
rs:WP_035193594	DNA topoisomerase I [Bacillus azotoformans].	25.38	461	267	20	22	452	197	610	2e-21	107
tr:A0A072NRK6_BACAZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.38	461	267	20	22	452	221	634	2e-21	107
rs:WP_028372589	DNA topoisomerase I [Legionella lansingensis].	27.74	411	242	15	60	452	247	620	2e-21	107
rs:WP_022702085	DNA topoisomerase I [Oceanicaulis alexandrii].	27.70	426	241	13	60	454	244	633	2e-21	107
rs:WP_012575317	DNA topoisomerase I [Anoxybacillus flavithermus].	25.47	428	248	17	50	452	227	608	2e-21	107
tr:C7GH19_9FIRM	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EEU98885.1};	29.15	295	184	8	160	445	3	281	2e-21	104
rs:WP_033629053	DNA topoisomerase, partial [Enterococcus faecium].	26.93	323	207	8	68	385	160	458	2e-21	106
rs:WP_021872352	DNA topoisomerase [Clostridium sp. CAG:1193].	26.77	452	261	16	22	450	192	596	2e-21	107
rs:XP_004259792	DNA topoisomerase 3-alpha, putative [Entamoeba invadens IP1].	27.59	377	223	12	32	392	246	588	2e-21	107
rs:WP_046514712	DNA topoisomerase I [Bacillus sp. SA1-12].	25.12	430	257	16	50	457	227	613	2e-21	107
rs:WP_039763835	DNA topoisomerase I [Caldicellulosiruptor sp. F32].	25.41	425	262	12	47	454	223	609	2e-21	107
rs:WP_027118545	DNA topoisomerase I [Lachnospiraceae bacterium YSB2008].	27.90	423	256	15	41	454	214	596	2e-21	107
rs:WP_043373106	DNA topoisomerase [Methylobacterium sp. L2-4].	28.40	426	272	13	40	439	236	654	2e-21	107
rs:WP_001286959	DNA topoisomerase I [Bacillus thuringiensis].	24.84	483	298	17	1	457	170	613	2e-21	107
rs:WP_026570374	MULTISPECIES: DNA topoisomerase I [Bacillaceae].	26.33	433	254	17	47	457	224	613	2e-21	107
rs:WP_016080527	MULTISPECIES: DNA topoisomerase 1 [Bacillus].	25.51	443	272	16	34	457	210	613	2e-21	107
tr:T0RST2_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.94	437	274	13	41	453	285	691	2e-21	107
rs:WP_032072231	DNA topoisomerase III [Escherichia coli].	36.88	160	101	0	36	195	246	405	3e-21	105
tr:A0A0D6NX78_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.02	442	255	17	47	452	231	636	3e-21	107
rs:WP_015604970	DNA topoisomerase I [Streptococcus oligofermentans].	24.54	436	254	13	40	452	227	610	3e-21	107
rs:WP_004891082	DNA topoisomerase I [Anoxybacillus flavithermus].	25.47	428	248	17	50	452	227	608	3e-21	107
rs:WP_041373011	DNA topoisomerase [Methylobacterium radiotolerans].	28.40	426	272	13	40	439	236	654	3e-21	107
rs:WP_010478322	endonuclease [Thermococcus zilligii].	28.18	401	197	15	112	457	828	1192	3e-21	107
tr:B9MM33_CALBD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.71	420	253	13	54	454	230	609	3e-21	107
rs:WP_041727195	DNA topoisomerase I [Caldicellulosiruptor bescii].	25.71	420	253	13	54	454	231	610	3e-21	107
rs:WP_040154376	hypothetical protein [Klebsiella pneumoniae].	33.90	177	108	4	289	459	1	174	3e-21	102
tr:B0TFR0_HELMI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.26	384	228	10	40	379	239	607	3e-21	107
tr:B1M8L6_METRJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.40	426	272	13	40	439	227	645	3e-21	107
rs:WP_048453176	DNA topoisomerase [Methylobacterium tarhaniae].	28.77	424	260	15	47	432	243	662	3e-21	107
tr:R0AE94_CLOBU	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.69	256	173	5	34	286	222	473	3e-21	105
tr:V8CP57_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETD29168.1};	29.48	268	177	6	160	425	2	259	3e-21	103
rs:WP_035779454	DNA topoisomerase III, partial [Clostridium butyricum].	29.69	256	173	5	34	286	222	473	3e-21	105
tr:A0A088TKF3_9MOLU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.11	452	263	16	22	451	192	594	3e-21	106
rs:WP_048171208	DNA topoisomerase I [Methanosarcina siciliae].	24.07	428	267	15	40	454	247	629	3e-21	107
rs:WP_019391804	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.94	433	261	15	47	457	224	614	3e-21	106
rs:WP_038467628	DNA topoisomerase I [Mollicutes bacterium HR1].	26.11	452	263	16	22	451	193	595	3e-21	106
tr:R2NSX6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.93	323	207	8	68	385	135	433	3e-21	106
rs:WP_036239280	DNA topoisomerase I [Marinospirillum insulare].	27.98	411	246	15	45	446	253	622	3e-21	107
rs:XP_008859836	DNA topoisomerase domain containing protein [Entamoeba nuttalli P19].	25.99	377	226	13	39	399	256	595	3e-21	106
rs:WP_010514841	DNA topoisomerase I [Komagataeibacter oboediens].	26.14	482	281	18	7	452	195	637	3e-21	107
tr:A0A0E9K5P0_9RHIZ	SubName: Full=Topoisomerase IA {ECO:0000313|EMBL:GAN48080.1};	28.40	426	272	13	40	439	227	645	3e-21	107
rs:WP_040980091	DNA topoisomerase I [Oceanobacillus sp. S5].	26.30	422	251	14	56	457	233	614	3e-21	106
rs:WP_003332525	DNA topoisomerase I [Bacillus azotoformans].	25.38	461	267	20	22	452	197	610	3e-21	106
rs:WP_011916787	DNA topoisomerase I [Caldicellulosiruptor saccharolyticus].	25.18	425	263	12	47	454	223	609	3e-21	106
rs:WP_003541173	DNA topoisomerase I [Desulfotomaculum nigrificans].	25.12	434	256	14	48	457	231	619	3e-21	106
tr:A0A0B5HW63_9ARCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.27	472	287	19	2	453	203	633	3e-21	106
tr:A0A0E3PD38_9EURY	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:AKB31979.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AKB31979.1};	24.07	428	267	15	40	454	247	629	3e-21	106
rs:WP_018292829	DNA topoisomerase I [Gallionella sp. SCGC AAA018-N21].	27.53	425	221	18	58	450	244	613	3e-21	107
rs:WP_032329999	DNA topoisomerase III, partial [Escherichia coli].	36.88	160	101	0	36	195	246	405	3e-21	104
rs:WP_025068440	DNA topoisomerase, partial [Prevotella denticola].	31.72	227	150	4	160	384	26	249	3e-21	103
rs:WP_027263490	DNA topoisomerase I [Sedimentitalea nanhaiensis].	29.30	430	246	16	47	452	231	626	3e-21	107
rs:WP_025439297	DNA topoisomerase I [Komagataeibacter xylinus].	25.78	481	284	17	7	452	195	637	3e-21	107
rs:WP_020156269	DNA topoisomerase I [Caldibacillus debilis].	25.81	430	254	16	50	457	227	613	3e-21	106
rs:WP_029667746	hypothetical protein, partial [Calescamantes bacterium JGI 0000106-I17].	26.54	407	247	14	59	450	243	612	3e-21	106
tr:A0A0B7MJT6_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.81	461	268	17	22	454	195	609	3e-21	106
rs:XP_009930649	PREDICTED: DNA topoisomerase 3-alpha [Opisthocomus hoazin].	26.52	445	262	16	39	456	290	696	3e-21	107
rs:WP_048437287	DNA topoisomerase, partial [Methylobacterium platani].	29.34	392	246	14	40	405	236	622	3e-21	106
rs:WP_046932689	hypothetical protein [Xanthomonas perforans].	26.90	420	246	13	60	459	236	614	3e-21	106
rs:WP_002111378	DNA topoisomerase I [Bacillus cereus].	24.43	483	300	16	1	457	170	613	3e-21	106
rs:WP_037000275	DNA topoisomerase III, partial [Pseudomonas fuscovaginae].	43.81	105	57	1	90	192	2	106	3e-21	98.6
rs:WP_041315236	hypothetical protein, partial [Heliobacterium modesticaldum].	25.26	384	228	10	40	379	239	607	3e-21	106
rs:WP_037236659	DNA topoisomerase I [Rhodomicrobium udaipurense].	27.21	441	258	13	43	452	226	634	3e-21	106
rs:WP_002173098	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.22	483	301	16	1	457	170	613	3e-21	106
rs:WP_045778769	DNA topoisomerase I [Methylococcaceae bacterium Sn10-6].	27.93	426	247	15	48	452	236	622	3e-21	106
rs:WP_032099733	DNA topoisomerase I [Anoxybacillus flavithermus].	24.12	485	289	18	1	452	170	608	4e-21	106
rs:WP_013459042	DNA topoisomerase I [Sulfuricurvum kujiense].	25.60	418	253	13	50	452	226	600	4e-21	106
rs:WP_044664589	DNA topoisomerase I [Syntrophaceticus schinkii].	25.81	461	268	17	22	454	191	605	4e-21	106
rs:WP_023043299	DNA topoisomerase III, partial [Enterococcus faecium].	31.54	241	149	6	57	292	268	497	4e-21	105
rs:WP_034722352	hypothetical protein, partial [Bacteriovorax sp. DB6_IX].	24.94	437	274	13	41	453	288	694	4e-21	106
rs:WP_036152236	DNA topoisomerase I [Lysinibacillus odysseyi].	25.86	437	256	17	40	452	217	609	4e-21	106
rs:WP_020294130	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	26.76	411	256	12	42	446	256	627	4e-21	106
tr:C3I4V3_BACTU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.51	443	272	16	34	457	180	583	4e-21	106
rs:WP_006575107	DNA topoisomerase I [Pseudoflavonifractor capillosus].	26.67	435	259	14	47	459	227	623	4e-21	106
tr:U2ITY5_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERJ70975.1};	28.62	276	180	7	112	384	2	263	4e-21	104
tr:A0A0D6JSG2_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.51	412	246	13	61	454	276	640	4e-21	106
rs:WP_034662386	DNA topoisomerase I [Bacillus pumilus].	24.94	433	254	15	50	457	227	613	4e-21	106
tr:A0A091VY07_OPIHO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.52	445	262	16	39	456	270	676	4e-21	106
tr:A0A0D6NH25_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.41	443	254	18	46	452	230	636	4e-21	106
rs:WP_015286106	topoisomerase IA [Methanoregula formicica].	25.32	387	215	13	85	449	284	618	4e-21	106
rs:WP_022792758	DNA topoisomerase I [Marinococcus halotolerans].	25.41	425	259	14	47	452	224	609	4e-21	106
rs:WP_026701049	DNA topoisomerase I [Bacillus aidingensis].	26.40	428	250	18	47	452	225	609	4e-21	106
rs:WP_037948397	DNA topoisomerase I [Sulfuricurvum sp. MLSB].	25.12	414	260	9	50	452	226	600	4e-21	106
rs:WP_044013492	hypothetical protein [Treponema sp. OMZ 838].	26.61	357	233	8	57	404	258	594	4e-21	106
rs:WP_039732367	DNA topoisomerase I [Komagataeibacter intermedius].	25.57	481	285	17	7	452	195	637	4e-21	106
tr:A0A0B3A5K8_9ARCH	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KHO45195.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KHO45195.1};	25.92	436	264	16	35	453	12	405	4e-21	105
rs:WP_017737335	topoisomerase I [Pseudomonas sp. CBZ-4].	28.36	409	244	16	47	446	259	627	4e-21	106
rs:WP_002146094	DNA topoisomerase I [Bacillus cereus].	25.28	443	273	15	34	457	210	613	4e-21	106
rs:WP_002295954	type I topoisomerase, partial [Enterococcus faecium].	33.96	212	121	6	254	455	1	203	4e-21	102
rs:WP_012939689	DNA topoisomerase I [Archaeoglobus profundus].	26.08	418	228	14	61	454	251	611	4e-21	106
rs:WP_041108973	MULTISPECIES: DNA topoisomerase I [Bacillus].	25.29	427	260	14	50	457	227	613	4e-21	106
rs:WP_046444718	DNA topoisomerase I [Catabacter hongkongensis].	27.54	472	262	19	18	457	182	605	4e-21	106
rs:WP_041789304	DNA topoisomerase I, partial [Rhodomicrobium vannielii].	27.21	441	258	13	43	452	226	634	4e-21	106
rs:WP_032825813	topoisomerase I, partial [Oenococcus oeni].	34.40	218	116	9	94	302	1	200	4e-21	101
rs:WP_034281770	DNA topoisomerase I [Bacillus safensis].	25.29	427	260	14	50	457	227	613	4e-21	106
rs:WP_007275720	DNA topoisomerase I [Haloferax sulfurifontis].	24.49	445	262	15	35	454	245	640	4e-21	106
rs:WP_040948662	DNA topoisomerase I [Paenibacillaceae bacterium G5].	25.92	436	252	16	49	458	226	616	4e-21	106
rs:WP_041020100	DNA topoisomerase I [Pseudomonas sp. SHC52].	28.61	409	243	16	47	446	259	627	4e-21	106
rs:WP_008181277	DNA topoisomerase I [Bacillus sp. B14905].	24.43	483	291	18	1	452	170	609	4e-21	106
rs:WP_004448953	DNA topoisomerase I [Acetobacter pasteurianus].	26.82	425	236	18	65	452	250	636	4e-21	106
tr:W1FAC4_ENTCL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	40.62	128	75	1	36	163	251	377	4e-21	104
rs:WP_001286957	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	25.51	443	272	16	34	457	210	613	4e-21	106
rs:WP_036171681	DNA topoisomerase I [Lysinibacillus massiliensis].	26.02	442	262	15	34	452	210	609	4e-21	106
rs:WP_002484856	DNA topoisomerase III [Staphylococcus epidermidis].	28.32	286	187	6	34	314	226	498	4e-21	105
rs:WP_031580966	DNA topoisomerase I [Lachnospiraceae bacterium AC2028].	25.46	432	251	12	47	454	226	610	4e-21	106
rs:WP_046384322	DNA topoisomerase I [Pseudomonas veronii].	28.36	409	244	16	47	446	259	627	4e-21	106
rs:WP_019864876	DNA topoisomerase I [Methylovulum miyakonense].	27.53	425	248	16	50	452	238	624	4e-21	106
rs:WP_001286956	DNA topoisomerase I [Bacillus thuringiensis].	25.51	443	272	16	34	457	210	613	4e-21	106
rs:WP_038004586	MULTISPECIES: DNA topoisomerase I [Thalassobacter].	28.94	432	237	17	48	454	242	628	4e-21	106
rs:WP_043074761	DNA topoisomerase [Methylobacterium radiotolerans].	28.40	426	272	13	40	439	236	654	4e-21	106
rs:WP_020959337	DNA topoisomerase I [Geobacillus sp. JF8].	25.31	490	287	18	1	457	170	613	4e-21	106
rs:WP_029604771	DNA topoisomerase I [Kozakia baliensis].	26.81	470	276	18	16	452	201	635	4e-21	106
rs:WP_024535012	DNA topoisomerase I [Sporosarcina sp. EUR3 2.2.2].	24.59	431	268	14	40	452	217	608	4e-21	106
rs:WP_002160736	DNA topoisomerase I [Bacillus cereus].	25.28	443	273	15	34	457	210	613	4e-21	106
rs:WP_022260022	DNA topoisomerase [Carnobacterium sp. N15.MGS-251].	23.64	461	258	15	47	449	225	649	4e-21	106
rs:WP_010530648	DNA topoisomerase I [Lentibacillus jeotgali].	24.74	489	292	17	1	457	170	614	4e-21	106
rs:WP_043267321	DNA topoisomerase I [Pseudomonas sp. AAC].	27.11	391	234	12	68	446	275	626	4e-21	106
rs:WP_024777914	DNA topoisomerase I [Pseudomonas corrugata].	28.61	409	243	16	47	446	259	627	4e-21	106
rs:WP_022509891	DNA topoisomerase [Clostridium sp. CAG:609].	25.99	481	284	16	1	457	171	603	4e-21	106
rs:WP_003212237	DNA topoisomerase I [Bacillus pumilus].	24.94	433	254	15	50	457	227	613	4e-21	106
rs:WP_026692501	DNA topoisomerase I [Bacillus kribbensis].	25.58	434	260	17	40	452	217	608	4e-21	106
rs:WP_020615298	DNA topoisomerase I [Paenibacillus daejeonensis].	25.90	471	275	16	18	457	187	614	5e-21	106
rs:WP_036859382	DNA topoisomerase I, partial [Prevotella disiens].	28.73	275	179	7	113	384	1	261	5e-21	103
rs:WP_020997791	DNA topoisomerase I [Streptococcus constellatus].	24.43	438	257	14	39	452	223	610	5e-21	106
rs:WP_017848775	topoisomerase I [Pseudomonas veronii].	28.36	409	244	16	47	446	259	627	5e-21	106
rs:WP_021317628	DNA topoisomerase I [Sphingobium ummariense].	28.38	437	251	17	40	452	219	617	5e-21	106
rs:WP_029435682	DNA topoisomerase I [Bilophila wadsworthia].	26.29	426	257	13	43	452	221	605	5e-21	106
rs:WP_010780938	DNA topoisomerase 1 [Enterococcus gilvus].	23.45	452	270	13	34	457	211	614	5e-21	106
rs:WP_019089708	DNA topoisomerase I [Acetobacter pasteurianus].	26.82	425	236	18	65	452	250	636	5e-21	106
rs:WP_033620255	DNA topoisomerase, partial [Enterococcus faecalis].	34.74	190	108	4	275	455	25	207	5e-21	102
rs:WP_021101011	DNA topoisomerase I [Litoreibacter arenae].	29.13	436	250	18	43	454	228	628	5e-21	106
rs:WP_037910128	DNA topoisomerase I [Sulfitobacter mediterraneus].	27.65	434	262	15	41	454	225	626	5e-21	106
rs:WP_027617977	DNA topoisomerase I [Pseudomonas sp. URHB0015].	27.67	412	251	14	42	446	256	627	5e-21	106
rs:WP_014586061	DNA topoisomerase I [Methanosaeta harundinacea].	25.44	452	274	17	18	454	213	616	5e-21	106
rs:WP_044141928	DNA topoisomerase I [Bacillus pumilus].	24.71	433	255	15	50	457	227	613	5e-21	105
rs:WP_002121782	DNA topoisomerase I [Bacillus cereus].	24.43	483	300	16	1	457	170	613	5e-21	105
rs:WP_019119105	DNA topoisomerase I [Brevibacillus massiliensis].	25.40	433	262	12	45	457	222	613	5e-21	105
rs:WP_036881465	DNA topoisomerase I, partial [Prevotella nigrescens].	28.62	276	178	6	113	384	1	261	5e-21	103
rs:WP_031368241	hypothetical protein, partial [Clostridium botulinum].	28.57	238	156	7	20	246	40	274	5e-21	102
rs:WP_017727299	DNA topoisomerase I [Bacillus sp. L1(2012)].	26.29	426	247	15	50	452	227	608	5e-21	105
rs:WP_046789963	DNA topoisomerase I [Salinicoccus halodurans].	23.82	424	265	13	47	452	223	606	5e-21	105
rs:WP_004970153	DNA topoisomerase I [Haloferax denitrificans].	24.32	444	264	15	35	454	245	640	5e-21	106
tr:C2XXU4_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.28	443	273	15	34	457	180	583	5e-21	105
tr:T0P3I5_PHOTE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQB98911.1};	36.26	171	100	4	289	459	1	162	5e-21	100
rs:WP_016994084	MULTISPECIES: DNA topoisomerase I [Lysinibacillus].	24.64	483	290	18	1	452	170	609	5e-21	105
sp:TOP1_METJA	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	26.07	468	270	19	18	459	220	637	5e-21	106
rs:WP_025080665	DNA topoisomerase I [Lactobacillus hamsteri].	26.60	406	239	13	69	457	259	622	5e-21	105
rs:WP_007697630	DNA topoisomerase I [Halovivax asiaticus].	23.93	422	276	13	40	452	249	634	5e-21	106
rs:WP_046406360	DNA topoisomerase I [Clostridium sp. A254.MGS-251].	23.64	461	258	15	47	449	225	649	5e-21	105
rs:WP_043319020	DNA topoisomerase I [Pseudomonas sp. PI1].	27.11	391	234	12	68	446	275	626	5e-21	106
rs:WP_025148338	DNA topoisomerase I [Bacillus sp. H1a].	25.06	443	274	15	34	457	210	613	5e-21	105
rs:WP_007933178	topoisomerase I [Pseudomonas sp. GM18].	29.20	411	234	18	49	446	261	627	5e-21	106
tr:E3HZ27_RHOVT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.21	441	258	13	43	452	226	634	5e-21	106
tr:C3IN36_BACTU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.51	443	272	16	34	457	169	572	5e-21	105
rs:WP_043904103	DNA topoisomerase I [Geobacillus stearothermophilus].	24.83	447	270	15	34	457	210	613	6e-21	105
rs:WP_033061924	DNA topoisomerase I [Pseudomonas mandelii].	29.06	413	236	18	47	446	259	627	6e-21	106
tr:C3AXE7_BACMY	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:EEM01684.1};	27.84	255	175	4	146	398	3	250	6e-21	101
rs:WP_042788503	DNA topoisomerase I [Acetobacter aceti].	26.59	425	237	18	65	452	250	636	6e-21	106
rs:WP_004229276	DNA topoisomerase I [Lysinibacillus fusiformis].	24.84	483	289	19	1	452	170	609	6e-21	105
rs:WP_003628391	DNA topoisomerase I [Acetobacter pasteurianus].	26.82	425	236	18	65	452	250	636	6e-21	106
tr:C3DNN3_BACTS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.51	443	272	16	34	457	102	505	6e-21	105
rs:WP_017548529	DNA topoisomerase I [Salinicoccus carnicancri].	23.12	480	299	16	1	452	169	606	6e-21	105
rs:WP_045215568	DNA topoisomerase I [Desulfobulbus alkaliphilus].	25.36	422	257	11	47	452	225	604	6e-21	105
rs:WP_044810431	DNA topoisomerase I [Bacillus cereus].	24.64	483	299	17	1	457	170	613	6e-21	105
rs:WP_047421310	DNA topoisomerase I [Bacillus anthracis].	24.22	483	301	16	1	457	170	613	6e-21	105
rs:WP_020800560	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	29.06	413	236	18	47	446	259	627	6e-21	105
tr:C2UZ72_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.64	483	299	17	1	457	140	583	6e-21	105
rs:WP_047703818	DNA topoisomerase I [Pseudomonas mediterranea].	28.61	409	243	16	47	446	259	627	6e-21	105
rs:WP_002347146	hypothetical protein, partial [Enterococcus faecium].	34.09	176	107	3	190	365	1	167	6e-21	102
rs:WP_006116241	DNA topoisomerase I [Acetobacter pomorum].	26.82	425	236	18	65	452	250	636	6e-21	105
rs:WP_021246507	DNA topoisomerase I [Sphingobium baderi].	28.21	436	253	16	40	452	219	617	6e-21	105
rs:WP_008226122	DNA topoisomerase I [Roseobacter sp. GAI101].	28.31	438	255	17	41	454	225	627	6e-21	105
rs:WP_009621355	DNA topoisomerase I [Pseudomonas sp. M1].	27.11	391	234	12	68	446	275	626	6e-21	105
rs:WP_003350210	DNA topoisomerase I [Bacillus methanolicus].	25.28	451	263	18	34	457	210	613	6e-21	105
rs:WP_001286962	DNA topoisomerase I [Bacillus cereus].	24.64	483	299	17	1	457	170	613	6e-21	105
rs:WP_046026992	DNA topoisomerase I [Pseudomonas fluorescens].	28.61	409	243	16	47	446	259	627	6e-21	105
rs:WP_040486417	DNA topoisomerase I [Listeria grayi].	24.95	485	295	18	1	457	170	613	6e-21	105
rs:WP_010456356	topoisomerase I [Pseudomonas mandelii].	29.06	413	236	18	47	446	259	627	6e-21	105
tr:A0A016WJY4_9BILA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.67	448	250	17	39	457	232	625	7e-21	105
rs:WP_014027527	DNA topoisomerase I [Acidithiobacillus ferrivorans].	30.10	412	215	19	70	454	257	622	7e-21	105
rs:WP_044330667	DNA topoisomerase I [Bacillus safensis].	24.94	433	254	15	50	457	227	613	7e-21	105
rs:WP_001286961	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	24.64	483	299	17	1	457	170	613	7e-21	105
rs:WP_046047844	DNA topoisomerase I [Pseudomonas fluorescens].	29.06	413	236	18	47	446	259	627	7e-21	105
rs:WP_015147956	DNA topoisomerase I [Oscillatoria acuminata].	28.93	356	214	11	41	387	249	574	7e-21	105
rs:WP_010719464	MULTISPECIES: DNA topoisomerase I [Enterococcus].	26.41	443	268	15	34	457	211	614	7e-21	105
rs:WP_044677372	DNA topoisomerase, partial [Streptococcus suis].	32.17	258	157	7	52	304	264	508	7e-21	105
rs:WP_038846550	DNA topoisomerase I [Pseudomonas fluorescens].	28.61	409	243	16	47	446	259	627	7e-21	105
rs:WP_043342545	DNA topoisomerase [Methylobacterium sp. EUR3 AL-11].	28.07	399	253	12	40	406	236	632	7e-21	105
rs:WP_042007418	hypothetical protein [Capnocytophaga canimorsus].	26.88	372	249	8	66	427	266	624	7e-21	105
rs:WP_038979973	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	29.06	413	236	18	47	446	259	627	7e-21	105
rs:WP_034606018	hypothetical protein, partial [Chitinimonas koreensis].	26.90	435	255	15	43	458	219	609	7e-21	105
rs:WP_044662359	DNA topoisomerase I [Sphingobium sp. YBL2].	28.38	437	251	17	40	452	219	617	7e-21	105
rs:WP_044050185	DNA topoisomerase I [Planktomarina temperata].	25.75	435	271	13	41	454	225	628	7e-21	105
rs:WP_045998281	DNA topoisomerase I [Loktanella sp. S4079].	28.31	431	241	17	48	454	242	628	7e-21	105
rs:WP_025547373	DNA topoisomerase I [Sphingobium sp. KK22].	28.38	437	251	17	40	452	219	617	7e-21	105
rs:WP_022434282	DNA topoisomerase [Mycoplasma sp. CAG:472].	25.21	468	290	14	1	450	171	596	7e-21	105
rs:WP_022282048	DNA topoisomerase [Clostridium sp. CAG:448].	26.40	428	241	13	47	446	270	651	7e-21	105
rs:WP_020082763	hypothetical protein [gamma proteobacterium SCGC AAA076-P09].	25.95	393	241	11	77	458	286	639	7e-21	105
rs:WP_011998043	DNA topoisomerase I [Ignicoccus hospitalis].	27.81	338	200	11	69	398	261	562	7e-21	105
rs:WP_011989128	hypothetical protein [Clostridium kluyveri].	25.72	381	240	13	77	444	280	630	7e-21	105
tr:D7UYI7_LISGR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.95	485	295	18	1	457	181	624	7e-21	105
rs:WP_010093441	DNA topoisomerase I [Ornithinibacillus scapharcae].	26.25	419	247	15	60	457	237	614	8e-21	105
rs:WP_021841057	DNA topoisomerase [Veillonella sp. CAG:933].	25.17	437	267	13	36	454	271	665	8e-21	105
rs:WP_003320692	DNA topoisomerase I [Bacillus alcalophilus].	26.12	425	249	17	50	452	227	608	8e-21	105
rs:WP_029565595	DNA topoisomerase I [Bacillus cibi].	25.12	426	254	16	54	457	231	613	8e-21	105
rs:XP_001739303	DNA topoisomerase 3-alpha [Entamoeba dispar SAW760].	25.62	363	223	10	39	392	256	580	8e-21	105
rs:WP_045542387	DNA topoisomerase I [Acetobacter tropicalis].	26.38	436	249	18	53	452	237	636	8e-21	105
rs:WP_017526655	topoisomerase I [Pseudomonas fluorescens].	28.61	409	243	16	47	446	259	627	8e-21	105
rs:WP_008073063	topoisomerase I [Pseudomonas sp. GM79].	29.06	413	236	18	47	446	259	627	8e-21	105
tr:C2WAW0_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.28	439	265	15	40	457	187	583	8e-21	105
rs:WP_010739369	DNA topoisomerase 1 [Enterococcus malodoratus].	23.93	443	279	13	34	457	211	614	8e-21	105
rs:WP_001286958	DNA topoisomerase I [Bacillus cereus].	24.79	484	297	18	1	457	170	613	8e-21	105
tr:D4C6D6_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.67	270	172	5	40	296	228	484	8e-21	104
rs:WP_021921659	DNA topoisomerase [Acholeplasma sp. CAG:878].	26.20	397	220	12	76	450	249	594	8e-21	105
rs:WP_012700082	topoisomerase I [Azotobacter vinelandii].	26.73	419	255	15	47	452	257	636	8e-21	105
rs:WP_008577482	MULTISPECIES: DNA topoisomerase I [Haloferax].	24.49	445	262	17	35	454	245	640	8e-21	105
rs:WP_019648305	topoisomerase I [Pseudomonas sp. 45MFCol3.1].	29.06	413	236	18	47	446	259	627	8e-21	105
rs:WP_004044253	MULTISPECIES: DNA topoisomerase I [Haloferax].	25.32	387	225	12	86	454	300	640	8e-21	105
rs:WP_016328687	DNA topoisomerase I [Thermus oshimai].	27.65	405	217	15	69	454	272	619	8e-21	105
rs:WP_029281361	DNA topoisomerase I [Bacillus indicus].	25.12	426	254	16	54	457	231	613	8e-21	105
rs:WP_034126645	DNA topoisomerase I [Pseudomonas fluorescens].	28.61	409	243	16	47	446	259	627	8e-21	105
rs:WP_033672103	DNA topoisomerase I [Bacillus gaemokensis].	25.28	439	265	15	40	457	217	613	8e-21	105
rs:WP_001286951	DNA topoisomerase I [Bacillus cereus].	25.28	439	265	15	40	457	217	613	8e-21	105
rs:WP_047166403	DNA topoisomerase I [Sphingomonas sp. Y57].	27.84	467	260	18	22	452	192	617	8e-21	105
rs:WP_025113925	DNA topoisomerase I [Lysinibacillus fusiformis].	25.69	436	258	17	40	452	217	609	8e-21	105
rs:WP_047151637	DNA topoisomerase I [Aneurinibacillus tyrosinisolvens].	25.29	427	256	16	47	452	224	608	8e-21	105
rs:WP_035119821	DNA topoisomerase I [Cohnella panacarvi].	24.36	468	286	13	18	457	187	614	9e-21	105
tr:A0A0C7RRP1_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.41	440	276	10	33	454	212	608	9e-21	105
rs:WP_017471872	DNA topoisomerase I [Amphibacillus jilinensis].	24.59	431	265	12	47	457	224	614	9e-21	105
rs:WP_032877218	DNA topoisomerase I [Pseudomonas sp. BRG-100].	28.61	409	243	16	47	446	259	627	9e-21	105
rs:WP_006892984	DNA topoisomerase I [Methylobacter tundripaludum].	28.40	426	241	18	50	452	238	622	9e-21	105
tr:T0DM55_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.17	441	271	15	41	453	289	698	9e-21	105
rs:WP_033655545	DNA topoisomerase, partial [Enterococcus faecium].	31.78	236	149	5	57	289	268	494	9e-21	104
rs:WP_004064987	DNA topoisomerase I [Haloferax lucentense].	25.32	387	225	12	86	454	300	640	9e-21	105
rs:WP_018660050	DNA topoisomerase I [Bacillus acidiproducens].	25.23	436	269	15	40	457	217	613	9e-21	105
rs:WP_012570516	DNA topoisomerase I [Coxiella burnetii].	26.53	426	253	13	48	452	236	622	9e-21	105
rs:WP_037997223	DNA topoisomerase I [Thermoactinomyces sp. Gus2-1].	23.85	436	261	11	47	457	224	613	9e-21	105
rs:WP_004285786	DNA topoisomerase I [Neisseria weaveri].	25.87	487	254	15	41	454	225	677	9e-21	105
rs:WP_018925317	MULTISPECIES: topoisomerase I [Pseudomonas].	29.06	413	236	18	47	446	259	627	9e-21	105
rs:WP_046847126	DNA topoisomerase I [Hyphomicrobium sp. GJ21].	27.43	452	256	15	43	452	227	648	9e-21	105
rs:WP_005786156	topoisomerase I [Pseudomonas synxantha].	28.61	409	243	16	47	446	259	627	9e-21	105
rs:WP_029195346	DNA topoisomerase I [Paenibacillus alginolyticus].	25.81	434	256	14	47	457	224	614	9e-21	105
rs:WP_008057949	topoisomerase I [Pseudomonas sp. GM78].	28.61	409	243	16	47	446	259	627	9e-21	105
rs:WP_012503239	DNA topoisomerase I [Chlorobaculum parvum].	24.65	434	259	14	47	451	235	629	9e-21	105
rs:WP_015300379	topoisomerase IA [Halovivax ruber].	23.70	422	277	13	40	452	271	656	9e-21	105
rs:WP_003797196	DNA topoisomerase I [Actinomyces odontolyticus].	28.14	366	215	12	42	385	253	592	9e-21	105
rs:WP_010026557	DNA topoisomerase I [Sporolactobacillus inulinus].	25.81	434	254	13	50	457	227	618	9e-21	105
tr:A0A0C7NLR7_9THEO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.68	431	252	16	49	457	227	615	9e-21	105
rs:WP_047761919	DNA topoisomerase I [Neisseria sp. KH1503].	24.38	484	265	10	41	454	225	677	1e-20	105
rs:WP_044525682	DNA topoisomerase I [Francisella philomiragia].	27.54	403	243	13	67	452	252	622	1e-20	105
rs:WP_042606500	DNA topoisomerase III, partial [Vibrio harveyi].	29.49	217	129	5	257	459	5	211	1e-20	101
rs:WP_006558567	DNA topoisomerase I [Acetobacter tropicalis].	26.38	436	249	18	53	452	237	636	1e-20	105
rs:WP_031382963	DNA topoisomerase I [Halomonas zincidurans].	28.11	402	233	14	65	452	283	642	1e-20	105
rs:WP_008028483	topoisomerase I [Pseudomonas sp. GM60].	28.61	409	243	16	47	446	259	627	1e-20	105
rs:WP_033843509	DNA topoisomerase I [Geobacillus subterraneus].	24.67	450	267	16	34	457	210	613	1e-20	105
rs:WP_048001567	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.82	427	262	14	50	457	227	613	1e-20	105
rs:WP_035379360	DNA topoisomerase I [Acetobacter tropicalis].	26.38	436	249	18	53	452	237	636	1e-20	105
rs:WP_008037710	topoisomerase I [Pseudomonas sp. GM67].	28.61	409	243	16	47	446	259	627	1e-20	105
rs:WP_030128417	DNA topoisomerase I [Pseudomonas sp. QTF5].	28.61	409	243	16	47	446	259	627	1e-20	105
rs:WP_048307244	DNA topoisomerase I [Halomonas sp. PR-M31].	28.26	414	244	15	51	452	270	642	1e-20	105
rs:WP_040314066	hypothetical protein, partial [Bacteriovorax sp. BAL6_X].	25.17	441	271	15	41	453	294	703	1e-20	105
rs:WP_012094926	DNA topoisomerase I [Bacillus cytotoxicus].	24.43	442	265	14	40	457	217	613	1e-20	105
rs:WP_002295723	type I topoisomerase, partial [Enterococcus faecium].	32.23	211	126	5	254	455	1	203	1e-20	100
tr:A0A0B3AMV3_9ARCH	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KHO51615.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KHO51615.1};	23.87	465	302	15	2	453	207	632	1e-20	105
tr:E2XNF4_PSEFL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.36	409	244	16	47	446	151	519	1e-20	105
rs:WP_013384550	DNA topoisomerase I [Ketogulonicigenium vulgare].	28.02	439	255	18	41	454	225	627	1e-20	105
rs:WP_017796659	DNA topoisomerase I [Oceanobacillus kimchii].	25.70	428	250	16	54	457	231	614	1e-20	105
rs:WP_009204281	DNA topoisomerase I [Anaerostipes hadrus].	25.70	428	259	13	48	457	227	613	1e-20	105
rs:WP_008391297	DNA topoisomerase I [Clostridium sp. SS2/1].	25.70	428	259	13	48	457	227	613	1e-20	105
rs:WP_006870710	DNA topoisomerase I [Legionella drancourtii].	26.74	475	276	18	3	452	195	622	1e-20	105
rs:WP_015863217	DNA topoisomerase I [Desulfovibrio magneticus].	26.92	416	244	13	54	452	232	604	1e-20	105
rs:WP_035735116	DNA topoisomerase I [Francisella philomiragia].	27.05	403	245	12	67	452	252	622	1e-20	105
rs:WP_043047499	DNA topoisomerase I [Pseudomonas fluorescens].	28.36	409	244	16	47	446	259	627	1e-20	105
rs:WP_027604240	DNA topoisomerase I [Pseudomonas sp. LAMO17WK12:I2].	28.36	409	244	16	47	446	259	627	1e-20	105
tr:A0A0D8IZI5_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.25	422	251	15	50	452	229	613	1e-20	105
rs:WP_044930417	DNA topoisomerase III, partial [Clostridium sp. M62/1].	26.92	260	164	5	40	286	228	474	1e-20	103
rs:WP_004057583	DNA topoisomerase I [Haloferax mediterranei].	24.94	413	243	13	61	454	276	640	1e-20	105
rs:WP_010563749	topoisomerase I [Pseudomonas extremaustralis].	28.36	409	244	16	47	446	259	627	1e-20	105
rs:WP_024074081	topoisomerase I [Pseudomonas sp. TKP].	28.36	409	244	16	47	446	259	627	1e-20	105
rs:WP_001286966	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	24.79	484	297	18	1	457	170	613	1e-20	105
rs:WP_028977943	DNA topoisomerase I [Sporolactobacillus terrae].	26.77	437	246	16	50	457	227	618	1e-20	105
rs:WP_034635714	DNA topoisomerase I [Bacillus manliponensis].	25.30	423	255	15	50	452	227	608	1e-20	105
rs:WP_016415618	topoisomerase I [Halomonas anticariensis].	28.70	439	246	20	35	452	250	642	1e-20	105
rs:WP_003791882	DNA topoisomerase I [Actinomyces odontolyticus].	28.14	366	215	12	42	385	253	592	1e-20	105
tr:V2LUX5_SALET	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	43.52	108	61	0	36	143	251	358	1e-20	102
rs:WP_034464002	MULTISPECIES: DNA topoisomerase I [Actinobacteria].	28.14	366	215	12	42	385	253	592	1e-20	105
rs:WP_039805487	DNA topoisomerase I [Azotobacter chroococcum].	27.45	419	252	14	47	452	257	636	1e-20	105
rs:WP_011979781	DNA topoisomerase I [Sulfurovum sp. NBC37-1].	27.48	444	251	16	31	452	209	603	1e-20	105
rs:WP_009053944	DNA topoisomerase I [Actinomyces sp. ICM39].	28.14	366	215	12	42	385	253	592	1e-20	105
rs:WP_027921688	DNA topoisomerase I [Pseudomonas sp. URMO17WK12:I12].	28.32	392	228	15	68	446	276	627	1e-20	105
rs:WP_022189573	DNA topoisomerase [Ruminococcus sp. CAG:177].	25.59	469	245	16	47	449	224	654	1e-20	105
rs:WP_015845040	DNA topoisomerase I [Paenibacillus sp. JDR-2].	26.27	434	250	16	49	457	226	614	1e-20	105
rs:WP_029439593	DNA topoisomerase I [Bacillus thuringiensis].	24.43	483	300	17	1	457	170	613	1e-20	105
rs:WP_011065946	DNA topoisomerase I [Oceanobacillus iheyensis].	25.70	428	250	17	54	457	231	614	1e-20	105
tr:W8YLE3_9BACL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.07	445	259	17	38	457	180	579	1e-20	104
rs:WP_042516839	DNA topoisomerase I [Francisella philomiragia].	27.05	403	245	12	67	452	252	622	1e-20	105
rs:WP_024809418	DNA topoisomerase I [Oceanicola sp. HL-35].	28.47	439	252	17	41	454	225	626	1e-20	105
rs:WP_013013879	DNA topoisomerase I [Meiothermus ruber].	28.02	414	224	16	61	452	246	607	1e-20	105
rs:WP_005772159	DNA topoisomerase I [Coxiella burnetii].	26.53	426	253	13	48	452	236	622	1e-20	105
rs:WP_033022990	DNA topoisomerase I [Geobacillus sp. G1w1].	24.67	450	267	16	34	457	210	613	1e-20	105
rs:WP_010546708	DNA topoisomerase I, partial [Halobiforma lacisalsi].	24.07	432	285	13	31	454	238	634	1e-20	105
rs:WP_008645712	hypothetical protein, partial [Bacteroides sp. 1_1_30].	33.33	222	138	7	60	280	263	475	1e-20	103
rs:WP_018658789	hypothetical protein [Allofustis seminis].	25.16	469	272	18	18	457	188	606	1e-20	104
tr:A0A096BQP1_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGF44992.1}; Flags: Fragment;	29.37	286	187	5	101	384	3	275	1e-20	102
rs:XP_010300310	PREDICTED: DNA topoisomerase 3-alpha [Balearica regulorum gibbericeps].	26.46	446	261	17	39	456	290	696	1e-20	105
rs:WP_034945828	DNA topoisomerase III, partial [Erwinia oleae].	39.85	133	79	1	36	167	242	374	1e-20	102
rs:WP_007087757	DNA topoisomerase I [Bacillus bataviensis].	26.43	420	243	18	60	457	240	615	1e-20	104
rs:WP_038036917	DNA topoisomerase I, partial [Thermopetrobacter sp. TC1].	27.99	443	250	14	47	454	231	639	1e-20	105
rs:WP_020322465	toprim domain protein, partial [Klebsiella pneumoniae].	40.91	154	85	3	27	178	239	388	1e-20	102
rs:WP_025128846	DNA topoisomerase I [Pseudomonas sp. PH1b].	27.81	392	230	15	68	446	276	627	1e-20	105
tr:A0A087V368_BALRE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.46	446	261	17	39	456	270	676	1e-20	105
rs:WP_046198501	DNA topoisomerase I [Bacillus sp. UMTAT18].	24.79	484	297	18	1	457	170	613	1e-20	104
tr:C3C6F6_BACTU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.79	484	297	18	1	457	163	606	1e-20	104
rs:WP_027433127	DNA topoisomerase I [Lachnospiraceae bacterium MD2004].	24.43	438	278	12	36	457	215	615	1e-20	104
tr:A0A0C7P0Z4_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.34	437	274	10	36	454	215	608	1e-20	104
rs:WP_018996076	DNA topoisomerase I [Hirschia maritima].	25.40	433	268	12	47	454	231	633	1e-20	105
rs:WP_010219084	DNA topoisomerase I [Sphingomonas sp. PAMC 26621].	28.17	465	261	18	22	452	192	617	1e-20	105
rs:WP_028467444	DNA topoisomerase I [Nisaea denitrificans].	26.30	441	261	14	45	452	228	637	1e-20	105
rs:WP_045175688	DNA topoisomerase I [Caldicellulosiruptor sp. Wai35.B1].	25.24	420	255	13	54	454	231	610	1e-20	104
rs:WP_027022206	DNA topoisomerase I [Conchiformibius steedae].	26.50	434	254	13	41	452	227	617	1e-20	105
tr:A0A0F5R1F5_9BACL	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KKC46776.1};	26.07	445	259	17	38	457	215	614	1e-20	104
rs:WP_017842229	DNA topoisomerase I [Methylomicrobium buryatense].	26.35	444	263	15	31	452	221	622	1e-20	105
rs:WP_022283279	DNA topoisomerase [Clostridium sp. CAG:417].	24.58	472	288	15	1	450	172	597	1e-20	104
rs:WP_042729272	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	28.36	409	244	16	47	446	259	627	1e-20	105
rs:WP_022796267	DNA topoisomerase I [Bavariicoccus seileri].	26.20	416	247	15	60	457	239	612	1e-20	104
rs:WP_021611891	DNA topoisomerase I [Actinomyces sp. oral taxon 172].	28.14	366	215	12	42	385	253	592	1e-20	105
rs:XP_010291976	PREDICTED: DNA topoisomerase 3-alpha [Phaethon lepturus].	26.29	445	263	16	39	456	290	696	1e-20	105
rs:WP_043304444	DNA topoisomerase I [Pseudomonas viridiflava].	27.94	408	247	14	47	446	259	627	1e-20	105
rs:WP_005769743	DNA topoisomerase I [Coxiella burnetii].	26.53	426	253	13	48	452	236	622	1e-20	104
rs:WP_010958589	DNA topoisomerase I [Coxiella burnetii].	26.53	426	253	13	48	452	236	622	1e-20	104
tr:A0A090QZ46_9GAMM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL07513.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL07513.1};	38.85	139	85	0	266	404	2	140	1e-20	99.4
rs:WP_009886426	DNA topoisomerase I [Ferroplasma acidarmanus].	26.02	369	224	11	34	392	219	548	1e-20	104
rs:WP_003234049	DNA topoisomerase I subunit omega [Pseudomonas fluorescens].	28.36	409	244	16	47	446	259	627	1e-20	105
rs:WP_041139083	DNA topoisomerase I [Clostridiaceae bacterium GM1].	26.63	413	228	14	61	450	239	599	1e-20	104
tr:A0A0A8VSW0_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.34	437	274	10	36	454	215	608	1e-20	104
rs:WP_013040040	DNA topoisomerase I [Sphingobium japonicum].	27.64	445	256	16	40	452	219	629	1e-20	105
rs:WP_035401765	DNA topoisomerase I, partial [Chlorobium sp. GBChlB].	26.85	432	249	15	47	449	228	621	1e-20	104
rs:WP_004286415	DNA topoisomerase I [Francisella philomiragia].	27.05	403	245	12	67	452	252	622	1e-20	104
rs:WP_028621958	DNA topoisomerase I [Pseudomonas sp. Ant30-3].	28.12	409	245	16	47	446	259	627	1e-20	105
rs:WP_013537158	DNA topoisomerase I [Thermovibrio ammonificans].	25.54	462	252	15	47	454	228	651	1e-20	104
rs:WP_001286972	DNA topoisomerase I [Bacillus cereus].	24.79	484	297	18	1	457	170	613	1e-20	104
tr:A0A091UUX7_PHALP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.29	445	263	16	39	456	270	676	1e-20	105
rs:WP_006269520	DNA topoisomerase I [Streptococcus constellatus].	24.20	438	258	14	39	452	223	610	1e-20	104
rs:WP_021228023	DNA topoisomerase I [Sphingobium lactosutens].	27.20	489	277	19	1	452	171	617	1e-20	104
rs:WP_029505861	DNA topoisomerase I [Lachnospiraceae bacterium AC2012].	24.20	438	279	12	36	457	215	615	1e-20	104
tr:R2RVG6_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.33	243	146	8	52	290	265	495	1e-20	103
rs:WP_046065291	DNA topoisomerase I [Pseudomonas kilonensis].	28.36	409	244	16	47	446	259	627	1e-20	104
rs:WP_025993435	DNA topoisomerase I [Pseudomonas viridiflava].	27.94	408	247	14	47	446	259	627	1e-20	104
rs:WP_033902579	DNA topoisomerase I [Pseudomonas sp. FH1].	28.61	409	243	16	47	446	259	627	1e-20	104
rs:WP_039677107	DNA topoisomerase I [Streptococcus constellatus].	24.20	438	258	14	39	452	223	610	1e-20	104
rs:WP_027439327	DNA topoisomerase I [Lachnospiraceae bacterium AC2031].	25.45	444	273	12	29	454	203	606	1e-20	104
rs:WP_035016504	DNA topoisomerase, partial [Enterococcus raffinosus].	33.33	243	146	8	52	290	265	495	1e-20	103
rs:WP_045503129	DNA topoisomerase I [Streptococcus gordonii].	23.67	431	264	12	40	452	227	610	1e-20	104
rs:WP_025385032	DNA topoisomerase I [Legionella oakridgensis].	27.32	410	243	14	61	452	248	620	1e-20	104
tr:G4L412_TETHN	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:BAK95691.1};	30.86	243	142	9	221	454	12	237	1e-20	101
rs:WP_008297203	DNA topoisomerase 1 [Bhargavaea cecembensis].	26.03	438	262	16	40	457	218	613	1e-20	104
rs:WP_020820769	MULTISPECIES: DNA topoisomerase I [Sphingobium].	27.64	445	256	16	40	452	219	629	1e-20	104
rs:WP_022418595	DNA topoisomerase [Acidiphilium sp. CAG:727].	25.91	386	238	12	77	449	285	635	1e-20	104
rs:WP_008527508	DNA topoisomerase I [Halorhabdus tiamatea].	25.19	401	259	11	60	454	265	630	1e-20	104
rs:WP_032865663	DNA topoisomerase I, partial [Pseudomonas fluorescens].	28.36	409	244	16	47	446	115	483	1e-20	104
tr:E8JTB1_STRCR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.90	431	263	12	40	452	230	613	2e-20	104
rs:WP_041592025	DNA topoisomerase, partial [Tetragenococcus halophilus].	30.86	243	142	9	221	454	7	232	2e-20	100
rs:WP_036217009	DNA topoisomerase I [Marinospirillum minutulum].	26.89	409	253	12	45	446	253	622	2e-20	104
rs:WP_006185387	DNA topoisomerase I [Natrinema pallidum].	23.94	426	274	13	40	454	263	649	2e-20	104
rs:WP_029241462	DNA topoisomerase I [Pseudomonas viridiflava].	27.94	408	247	14	47	446	259	627	2e-20	104
rs:WP_007256547	DNA topoisomerase I [Oceanicola granulosus].	26.09	437	267	15	41	454	225	628	2e-20	104
rs:WP_012279897	DNA topoisomerase I [Francisella philomiragia].	27.54	403	243	13	67	452	252	622	2e-20	104
rs:XP_006048918	PREDICTED: DNA topoisomerase 3-alpha [Bubalus bubalis].	26.59	425	241	14	60	455	310	692	2e-20	104
rs:WP_045497387	DNA topoisomerase I [Streptococcus cristatus].	23.90	431	263	12	40	452	227	610	2e-20	104
tr:K1SSS7_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central domain protein {ECO:0000313|EMBL:EKC60568.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EKC60568.1}; Flags: Fragment;	32.57	218	126	7	182	392	7	210	2e-20	99.8
rs:WP_005944379	DNA topoisomerase I [Faecalibacterium prausnitzii].	27.08	432	249	16	45	452	222	611	2e-20	104
rs:WP_003183422	topoisomerase I [Pseudomonas fluorescens].	28.36	409	244	16	47	446	259	627	2e-20	104
rs:WP_009056800	DNA topoisomerase I [Atopobium sp. ICM58].	28.14	366	215	12	42	385	253	592	2e-20	104
rs:WP_037476183	DNA topoisomerase I [Snodgrassella alvi].	24.77	436	256	12	43	452	227	616	2e-20	104
rs:WP_003189652	MULTISPECIES: topoisomerase I [Pseudomonas].	28.61	409	243	16	47	446	259	627	2e-20	104
rs:WP_032888794	DNA topoisomerase I [Pseudomonas sp. RIT357].	28.36	409	244	16	47	446	259	627	2e-20	104
rs:WP_047710332	DNA topoisomerase I [Pseudomonas fluorescens].	28.61	409	243	16	47	446	259	627	2e-20	104
rs:WP_007140501	DNA topoisomerase I [Halobiforma lacisalsi].	24.07	432	285	13	31	454	238	634	2e-20	104
rs:WP_004323380	DNA topoisomerase III [Bacteroides ovatus].	26.05	334	208	9	61	385	263	566	2e-20	104
rs:WP_047672803	DNA topoisomerase I [Paenibacillus chondroitinus].	26.15	436	252	17	47	457	224	614	2e-20	104
tr:B9IVC2_BACCQ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.79	484	297	18	1	457	71	514	2e-20	104
rs:WP_031418983	DNA topoisomerase I [Lysinibacillus sphaericus].	24.22	483	292	18	1	452	170	609	2e-20	104
rs:WP_001235771	hypothetical protein, partial [Salmonella enterica].	37.16	148	93	0	36	183	246	393	2e-20	102
tr:F5X1Y0_STRPX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.00	337	209	8	67	398	234	538	2e-20	103
rs:WP_044720911	DNA topoisomerase [Streptococcus suis].	28.02	339	203	11	67	398	270	574	2e-20	104
rs:WP_040063189	DNA topoisomerase I [Pseudomonas batumici].	27.18	412	253	14	42	446	256	627	2e-20	104
tr:C2QFW7_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.79	484	297	18	1	457	140	583	2e-20	104
rs:WP_022409634	DNA topoisomerase [Clostridium sp. CAG:354].	27.89	294	179	9	77	357	283	556	2e-20	104
rs:WP_025027668	DNA topoisomerase I [Bacillus mannanilyticus].	22.11	484	311	15	1	457	169	613	2e-20	104
rs:WP_042535048	DNA topoisomerase I [Oceanobacillus oncorhynchi].	25.59	422	254	14	56	457	233	614	2e-20	104
rs:WP_005591982	MULTISPECIES: DNA topoisomerase I [Streptococcus].	23.90	431	263	12	40	452	227	610	2e-20	104
rs:WP_015371522	DNA topoisomerase I subunit omega [Pseudomonas poae].	28.36	409	244	16	47	446	259	627	2e-20	104
rs:WP_014259387	DNA topoisomerase I [Desulfovibrio africanus].	25.93	428	257	12	47	450	225	616	2e-20	104
rs:WP_047818127	DNA topoisomerase I [Geobacillus sp. 12AMOR1].	24.85	487	293	17	1	457	170	613	2e-20	104
rs:WP_040105642	DNA topoisomerase I [Salinicoccus roseus].	24.30	428	258	16	47	452	223	606	2e-20	104
rs:WP_003050739	DNA topoisomerase I [Streptococcus dysgalactiae].	23.96	455	277	15	19	452	213	619	2e-20	104
rs:WP_037011197	DNA topoisomerase I [Pseudomonas lutea].	26.76	411	256	12	42	446	255	626	2e-20	104
rs:XP_006024099	PREDICTED: DNA topoisomerase 3-alpha [Alligator sinensis].	26.17	447	261	16	39	456	205	611	2e-20	104
rs:WP_019818246	DNA topoisomerase I [Pseudomonas sp. CFT9].	28.61	409	243	16	47	446	259	627	2e-20	104
rs:WP_009322477	DNA topoisomerase I [Subdoligranulum sp. 4_3_54A2FAA].	27.01	422	252	15	50	452	229	613	2e-20	104
rs:WP_025046431	DNA topoisomerase I [Sulfitobacter mediterraneus].	28.15	437	256	17	41	454	225	626	2e-20	104
tr:A0A091CCP3_9ENTE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.72	449	268	15	34	457	211	614	2e-20	104
rs:WP_047227206	DNA topoisomerase I [Pseudomonas brassicacearum].	28.36	409	244	16	47	446	259	627	2e-20	104
rs:WP_009800677	DNA topoisomerase I [Oceanicaulis sp. HTCC2633].	26.70	427	256	12	54	454	238	633	2e-20	104
rs:WP_017380848	DNA topoisomerase I [Paenisporosarcina sp. TG-14].	24.88	434	263	14	40	452	217	608	2e-20	104
rs:WP_028692739	DNA topoisomerase I [Pseudomonas mosselii].	28.12	409	245	15	47	446	258	626	2e-20	104
rs:WP_037004128	hypothetical protein, partial [Pseudomonas fuscovaginae].	44.44	99	53	1	90	186	2	100	2e-20	96.3
rs:WP_039178505	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.71	433	255	15	50	457	227	613	2e-20	104
rs:WP_010161805	DNA topoisomerase I [Sphingomonas sp. PAMC 26617].	28.39	465	260	18	22	452	192	617	2e-20	104
rs:WP_045096318	DNA topoisomerase I [Legionella fallonii].	28.85	409	229	14	65	452	254	621	2e-20	104
rs:XP_005964996	PREDICTED: DNA topoisomerase 3-alpha [Pantholops hodgsonii].	26.82	425	240	14	60	455	351	733	2e-20	104
tr:A0A0C7RVM9_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.34	437	274	10	36	454	215	608	2e-20	104
rs:WP_014600791	DNA topoisomerase I [Listeria monocytogenes].	25.28	451	263	18	29	452	205	608	2e-20	104
tr:C3V9X4_9PSED	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.21	408	250	13	47	446	257	625	2e-20	104
tr:A0A0C7GJT9_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.34	437	274	10	36	454	215	608	2e-20	104
tr:A0A0C7IC58_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.34	437	274	10	36	454	215	608	2e-20	104
tr:A0A0A1SK48_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.34	437	274	10	36	454	215	608	2e-20	104
tr:A0A0C7QKE4_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.34	437	274	10	36	454	215	608	2e-20	104
rs:WP_001286952	DNA topoisomerase I [Bacillus cereus].	24.79	484	297	18	1	457	170	613	2e-20	104
rs:WP_013451230	DNA topoisomerase I [Calditerrivibrio nitroreducens].	24.47	425	268	10	43	452	220	606	2e-20	104
rs:WP_036832001	DNA topoisomerase I [Pontibacillus litoralis].	24.58	472	281	18	18	457	187	615	2e-20	104
rs:WP_017477200	topoisomerase I [Pseudomonas sp. PAMC 26793].	28.36	409	244	16	47	446	259	627	2e-20	104
rs:XP_005887347	PREDICTED: DNA topoisomerase 3-alpha [Bos mutus].	26.59	425	241	14	60	455	310	692	2e-20	104
rs:WP_009092271	protein TopB, partial [Elizabethkingia anophelis].	30.43	161	105	2	77	234	1	157	2e-20	99.0
rs:WP_024424184	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.71	433	255	15	50	457	227	613	2e-20	104
rs:XP_011455653	PREDICTED: DNA topoisomerase 3-alpha-like isoform X3 [Crassostrea gigas].	25.39	445	264	14	40	456	207	611	2e-20	104
rs:WP_028093990	DNA topoisomerase I [Pseudodonghicola xiamenensis].	28.41	433	249	16	47	454	231	627	2e-20	104
rs:WP_035662616	DNA topoisomerase I [Bacillus akibai].	25.87	429	246	17	50	452	227	609	2e-20	104
rs:WP_008151419	topoisomerase I [Pseudomonas sp. GM41(2012)].	28.81	413	237	18	47	446	259	627	2e-20	104
rs:XP_009466099	PREDICTED: DNA topoisomerase 3-alpha [Nipponia nippon].	26.52	445	262	16	39	456	290	696	2e-20	104
rs:WP_022374432	DNA topoisomerase [Firmicutes bacterium CAG:270].	25.70	428	259	13	48	457	227	613	2e-20	104
rs:WP_003218973	MULTISPECIES: topoisomerase I [Pseudomonas].	28.36	409	244	16	47	446	259	627	2e-20	104
rs:XP_010841206	PREDICTED: DNA topoisomerase 3-alpha [Bison bison bison].	26.59	425	241	14	60	455	310	692	2e-20	104
tr:A0A0C7SWK7_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.34	437	274	10	36	454	215	608	2e-20	104
rs:WP_010176358	topoisomerase I [Pseudomonas sp. PAMC 25886].	28.36	409	244	16	47	446	259	627	2e-20	104
tr:S4W680_STRAG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.00	337	209	8	67	398	270	574	2e-20	103
rs:WP_032517408	DNA topoisomerase III, partial [Peptoclostridium difficile].	29.12	261	168	6	32	286	216	465	2e-20	103
rs:WP_023495199	DNA topoisomerase 1 [Methyloglobulus morosus].	27.90	423	232	17	59	452	244	622	2e-20	104
rs:WP_016460876	DNA topoisomerase I [Actinomyces sp. HPA0247].	28.14	366	215	12	42	385	253	592	2e-20	104
rs:WP_042160445	DNA topoisomerase I [Paenibacillus sp. G1].	25.75	431	254	14	50	457	227	614	2e-20	104
rs:WP_044286837	DNA topoisomerase I [Pseudomonas fluorescens].	28.36	409	244	16	47	446	259	627	2e-20	104
rs:WP_010212072	MULTISPECIES: topoisomerase I [Pseudomonas].	28.36	409	244	16	47	446	259	627	2e-20	104
rs:WP_017254452	topoisomerase I [Pseudomonas tolaasii].	28.36	409	244	16	47	446	259	627	2e-20	104
rs:WP_026689912	DNA topoisomerase I [Bacillus aurantiacus].	25.69	436	253	18	47	457	224	613	2e-20	103
rs:WP_008007080	topoisomerase I [Pseudomonas sp. GM50].	28.81	413	237	18	47	446	259	627	2e-20	104
tr:K1S1X7_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EKC54717.1};	26.87	402	231	13	65	450	243	597	2e-20	103
rs:WP_026590316	DNA topoisomerase I [Bacillus sp. UNC437CL72CviS29].	25.11	438	267	15	40	457	217	613	2e-20	103
tr:A0A094LFW4_ANTCR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.74	445	261	16	39	456	270	676	2e-20	104
rs:WP_028790321	DNA topoisomerase I [Tetragenococcus muriaticus].	24.72	449	268	15	34	457	211	614	2e-20	103
tr:A0A093LKR5_FULGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.52	445	262	16	39	456	270	676	2e-20	104
rs:XP_011455651	PREDICTED: DNA topoisomerase 3-alpha-like isoform X1 [Crassostrea gigas].	25.62	445	263	15	40	456	207	611	2e-20	104
rs:XP_008926440	PREDICTED: DNA topoisomerase 3-alpha [Manacus vitellinus].	26.01	446	263	16	39	456	268	674	2e-20	104
rs:WP_039669638	DNA topoisomerase I [Coxiella burnetii].	26.53	426	253	13	48	452	236	622	2e-20	104
rs:WP_022029016	DNA topoisomerase [Clostridium sp. CAG:762].	26.63	398	239	11	66	450	240	597	2e-20	103
tr:A7LUK2_BACO1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.35	334	207	9	61	385	263	566	2e-20	103
rs:WP_036202949	DNA topoisomerase I [Lysinibacillus sinduriensis].	27.11	439	248	19	40	452	217	609	2e-20	103
rs:WP_010962038	DNA topoisomerase I [Methylococcus capsulatus].	28.02	439	235	19	45	452	233	621	2e-20	104
rs:XP_010170981	PREDICTED: DNA topoisomerase 3-alpha [Caprimulgus carolinensis].	26.74	445	261	16	39	456	290	696	2e-20	104
rs:WP_017648013	DNA topoisomerase [Streptococcus agalactiae].	27.00	337	209	8	67	398	270	574	2e-20	103
tr:A0A091VA01_NIPNI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.52	445	262	16	39	456	270	676	2e-20	104
tr:C7H3L1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.64	256	160	8	37	286	214	460	2e-20	103
rs:WP_013214669	DNA topoisomerase I [Hyphomicrobium denitrificans].	27.65	452	255	16	43	452	227	648	2e-20	104
rs:XP_011455654	PREDICTED: DNA topoisomerase 3-alpha-like isoform X4 [Crassostrea gigas].	25.39	445	264	14	40	456	207	611	2e-20	104
rs:XP_009581158	PREDICTED: DNA topoisomerase 3-alpha [Fulmarus glacialis].	26.52	445	262	16	39	456	290	696	2e-20	104
rs:WP_025044027	DNA topoisomerase I [Sulfitobacter geojensis].	27.69	437	259	16	41	454	225	627	2e-20	104
tr:V1CS44_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.42	427	272	11	45	457	250	635	2e-20	103
rs:WP_045773382	DNA topoisomerase I [Streptococcus sanguinis].	23.67	431	264	12	40	452	227	610	2e-20	103
rs:WP_045168977	DNA topoisomerase I [Caldicellulosiruptor sp. Rt8.B8].	26.00	427	258	12	47	454	223	610	2e-20	103
rs:WP_027149269	DNA topoisomerase I [Methylobacter tundripaludum].	28.00	425	244	17	50	452	238	622	2e-20	103
rs:WP_031563836	DNA topoisomerase I [Legionella wadsworthii].	28.18	433	240	18	46	452	234	621	2e-20	103
rs:WP_020857203	DNA topoisomerase I [SAR86 cluster bacterium SAR86A].	26.95	397	231	15	77	458	286	638	2e-20	104
rs:WP_005029320	DNA topoisomerase I [Bilophila wadsworthia].	26.30	422	254	13	47	452	225	605	2e-20	103
rs:WP_022628183	DNA topoisomerase I [Bacillus marmarensis].	25.59	426	252	17	49	452	226	608	2e-20	103
tr:K2GJ82_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKE30519.1};	27.69	260	174	6	198	454	1	249	2e-20	100
rs:WP_010544015	DNA topoisomerase I [Sphingomonas elodea].	27.82	435	248	15	43	452	224	617	2e-20	104
rs:XP_011455652	PREDICTED: DNA topoisomerase 3-alpha-like isoform X2 [Crassostrea gigas].	25.62	445	263	15	40	456	207	611	2e-20	104
rs:WP_025295581	DNA topoisomerase I [Sphingomonas sanxanigenens].	27.47	466	263	16	22	452	192	617	2e-20	104
rs:WP_029659198	DNA topoisomerase, partial [Enterococcus faecalis].	34.22	187	107	4	278	455	5	184	2e-20	99.4
rs:WP_021236566	MULTISPECIES: DNA topoisomerase I [Sphingomonadaceae].	27.84	449	250	17	40	452	219	629	2e-20	104
rs:WP_012959400	DNA topoisomerase I [Bacillus pseudofirmus].	25.59	426	252	17	49	452	226	608	2e-20	103
rs:WP_040955680	DNA topoisomerase I [Virgibacillus sp. SK37].	25.93	432	252	17	50	457	227	614	2e-20	103
rs:WP_042979410	DNA topoisomerase I [Bacillus mycoides].	25.68	444	270	17	34	457	210	613	2e-20	103
rs:WP_017752917	hypothetical protein [Clostridium tyrobutyricum].	24.87	394	262	10	47	427	250	622	2e-20	103
rs:WP_034928589	DNA topoisomerase I [Komagataeibacter rhaeticus].	26.57	414	243	14	70	452	254	637	2e-20	104
rs:WP_026485929	DNA topoisomerase I [Caldanaerobius polysaccharolyticus].	24.12	481	298	15	1	454	170	610	2e-20	103
rs:WP_040466951	DNA topoisomerase I [Eubacterium brachy].	23.42	427	272	11	45	457	215	600	3e-20	103
tr:A8AXH4_STRGC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.67	431	264	12	40	452	230	613	3e-20	103
rs:WP_035411959	DNA topoisomerase I [Bacillus sp. SJS].	24.72	445	272	13	34	457	210	612	3e-20	103
rs:WP_029098937	DNA topoisomerase I [Brevibacillus thermoruber].	25.39	445	265	14	36	457	213	613	3e-20	103
rs:WP_007399927	DNA topoisomerase I [Gluconacetobacter sp. SXCC-1].	26.57	414	243	14	70	452	254	637	3e-20	104
rs:WP_019405754	topoisomerase I [Pseudomonas stutzeri].	25.59	422	264	12	42	452	253	635	3e-20	103
rs:WP_003349030	DNA topoisomerase I [Bacillus methanolicus].	24.77	432	256	16	50	457	227	613	3e-20	103
rs:WP_021219539	topoisomerase I [Pseudomonas alcaligenes].	27.21	408	250	13	47	446	258	626	3e-20	103
rs:WP_048176475	DNA topoisomerase [Methanosarcina barkeri].	25.93	459	262	17	27	454	251	662	3e-20	103
rs:WP_035393821	DNA topoisomerase III, partial [Faecalibacterium prausnitzii].	31.64	256	160	8	37	286	232	478	3e-20	102
rs:WP_044898007	DNA topoisomerase I [Aeribacillus pallidus].	25.17	445	266	14	36	457	213	613	3e-20	103
rs:WP_048120819	DNA topoisomerase [Methanosarcina barkeri].	25.93	459	262	17	27	454	251	662	3e-20	103
rs:WP_016971417	topoisomerase I [Pseudomonas tolaasii].	28.36	409	244	16	47	446	259	627	3e-20	103
rs:WP_028941161	DNA topoisomerase I [Pseudomonas umsongensis].	28.81	413	237	18	47	446	259	627	3e-20	103
rs:WP_010772513	DNA topoisomerase 1 [Enterococcus caccae].	25.40	441	265	18	34	452	211	609	3e-20	103
rs:WP_015319853	DNA topoisomerase I [Natronococcus occultus].	24.59	427	271	14	40	454	246	633	3e-20	103
rs:WP_038144779	DNA topoisomerase I [Thioclava sp. 13D2W-2].	25.40	437	268	12	41	454	222	623	3e-20	103
rs:WP_011177548	DNA topoisomerase I [Picrophilus torridus].	25.28	352	220	11	41	387	238	551	3e-20	103
tr:C2S7N1_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.59	484	298	18	1	457	140	583	3e-20	103
rs:WP_017519284	topoisomerase I [Pseudomonas nitroreducens].	26.28	411	258	11	42	446	254	625	3e-20	103
rs:WP_043752749	DNA topoisomerase I, partial [Thiorhodococcus sp. AK35].	27.34	417	242	13	59	452	242	620	3e-20	103
rs:WP_021898243	DNA topoisomerase [Faecalibacterium sp. CAG:1138].	26.36	459	271	20	18	451	208	624	3e-20	103
rs:WP_045479482	DNA topoisomerase I [Bacillus sp. TS-2].	23.44	482	296	18	1	452	170	608	3e-20	103
rs:WP_007907779	topoisomerase I [Pseudomonas sp. GM102].	28.81	413	237	18	47	446	259	627	3e-20	103
tr:A9D533_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.81	414	245	12	70	452	293	679	3e-20	103
tr:C2MPG2_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.59	484	298	18	1	457	163	606	3e-20	103
rs:WP_022736269	DNA topoisomerase I [Laceyella sacchari].	26.51	430	247	15	47	452	224	608	3e-20	103
rs:WP_028619418	DNA topoisomerase I [Pseudomonas sp. 2-92(2010)].	28.36	409	244	16	47	446	259	627	3e-20	103
rs:WP_042490506	DNA topoisomerase I [Sphingomonas parapaucimobilis].	26.86	484	285	18	1	452	171	617	3e-20	103
rs:WP_020675223	hypothetical protein [Geopsychrobacter electrodiphilus].	25.71	459	276	17	24	454	201	622	3e-20	103
rs:WP_036778667	DNA topoisomerase I [Pontibacillus chungwhensis].	24.77	428	269	12	47	457	224	615	3e-20	103
rs:WP_046022277	DNA topoisomerase I [Magnetospira sp. QH-2].	27.19	434	236	16	59	452	240	633	3e-20	103
rs:WP_043243916	DNA topoisomerase I [Pseudomonas alcaligenes].	27.21	408	250	13	47	446	258	626	3e-20	103
rs:WP_041789689	MULTISPECIES: DNA topoisomerase I [Streptococcus].	23.67	431	264	12	40	452	227	610	3e-20	103
rs:WP_041723101	DNA topoisomerase I [Caldicellulosiruptor hydrothermalis].	25.24	420	255	13	54	454	231	610	3e-20	103
rs:WP_043640256	DNA topoisomerase I [Desulfovibrio sp. TomC].	26.65	409	247	12	60	459	236	600	3e-20	103
rs:WP_022447817	DNA topoisomerase [Firmicutes bacterium CAG:460].	23.37	505	295	13	1	449	171	639	3e-20	103
rs:WP_012722846	topoisomerase I [Pseudomonas fluorescens].	28.12	409	245	16	47	446	259	627	3e-20	103
rs:WP_034102544	DNA topoisomerase I [Pseudomonas fluorescens].	28.12	409	245	16	47	446	259	627	3e-20	103
rs:WP_008026309	DNA topoisomerase III [Bacteroides xylanisolvens].	26.05	334	208	9	61	385	263	566	3e-20	103
rs:WP_033624486	DNA topoisomerase, partial [Enterococcus faecalis].	31.75	252	154	7	52	298	127	365	3e-20	101
tr:E4QCU7_CALH1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.24	420	255	13	54	454	230	609	3e-20	103
rs:WP_007986365	topoisomerase I [Pseudomonas sp. GM48].	28.61	409	243	16	47	446	259	627	3e-20	103
rs:WP_046165540	DNA topoisomerase I [Streptococcus gordonii].	23.67	431	264	12	40	452	227	610	3e-20	103
tr:T1ZVG1_STRAP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.53	424	249	13	50	452	237	610	3e-20	103
rs:WP_011371807	DNA topoisomerase I [Sulfurimonas denitrificans].	25.12	434	253	14	41	452	218	601	3e-20	103
rs:WP_026683990	DNA topoisomerase I [Bacillus coagulans].	25.22	456	273	18	26	457	202	613	3e-20	103
rs:WP_020992625	DNA topoisomerase 1 [Streptococcus sp. 2_1_36FAA].	23.67	431	264	12	40	452	227	610	3e-20	103
rs:WP_046762942	DNA topoisomerase I [Sphingobium chungbukense].	27.92	437	253	17	40	452	219	617	3e-20	103
rs:WP_015790454	DNA topoisomerase I [Halorhabdus utahensis].	25.50	404	254	13	60	454	265	630	3e-20	103
rs:WP_031587734	DNA topoisomerase I [Lachnospiraceae bacterium P6A3].	25.40	441	258	16	38	454	217	610	3e-20	103
rs:WP_045617272	DNA topoisomerase I [Streptococcus mitis].	24.82	411	244	12	60	452	248	611	3e-20	103
rs:WP_009379579	DNA topoisomerase I [Bilophila sp. 4_1_30].	26.30	422	254	13	47	452	225	605	3e-20	103
rs:WP_034118691	DNA topoisomerase I [Pseudomonas fluorescens].	28.12	409	245	16	47	446	259	627	3e-20	103
rs:WP_025346247	DNA topoisomerase I [Sulfurospirillum multivorans].	26.83	436	243	17	41	452	218	601	3e-20	103
rs:XP_010211313	PREDICTED: DNA topoisomerase 3-alpha [Tinamus guttatus].	26.52	445	262	16	39	456	290	696	3e-20	103
rs:WP_005368869	MULTISPECIES: DNA topoisomerase I [Methylomicrobium].	27.11	439	253	18	41	452	225	623	3e-20	103
tr:E6J331_STRAP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.53	424	249	13	50	452	240	613	3e-20	103
rs:WP_039772798	DNA topoisomerase I [Pseudomonas fluorescens].	27.88	391	229	15	69	446	277	627	3e-20	103
rs:WP_036737880	DNA topoisomerase I [Paracoccus halophilus].	26.11	429	256	13	51	454	233	625	3e-20	103
rs:WP_027367012	DNA topoisomerase I [Desulfovibrio africanus].	25.65	425	262	11	47	450	225	616	3e-20	103
rs:WP_039718007	DNA topoisomerase I [Scytonema millei].	27.25	444	254	16	43	454	226	632	3e-20	103
rs:WP_033799367	DNA topoisomerase I, partial [Bacillus pseudomycoides].	28.15	270	171	7	192	454	1	254	3e-20	100
rs:WP_001286973	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	24.59	484	298	18	1	457	170	613	3e-20	103
rs:WP_025858485	DNA topoisomerase I [Pseudomonas sp. CHM02].	28.12	409	245	16	47	446	259	627	3e-20	103
rs:WP_007961815	topoisomerase I [Pseudomonas sp. GM30].	28.12	409	245	16	47	446	259	627	3e-20	103
rs:WP_041784112	DNA topoisomerase I, partial [Streptococcus anginosus].	24.53	424	249	13	50	452	237	610	3e-20	103
rs:WP_038413679	DNA topoisomerase I [Bacillus thuringiensis].	24.22	483	301	17	1	457	170	613	3e-20	103
tr:J6Y817_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJY35264.1}; Flags: Fragment;	36.48	159	92	3	207	365	2	151	3e-20	97.1
rs:WP_013159046	DNA topoisomerase I [Meiothermus silvanus].	26.52	411	228	15	61	452	247	602	3e-20	103
rs:WP_005964300	DNA topoisomerase I [endosymbiont of Riftia pachyptila].	26.65	409	248	12	61	452	246	619	3e-20	103
tr:A0A0B1TGI7_OESDE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.80	444	250	19	39	457	206	599	4e-20	103
rs:WP_010759374	DNA topoisomerase 1 [Enterococcus pallens].	23.90	431	253	12	54	457	232	614	4e-20	103
rs:WP_016975262	topoisomerase I [Pseudomonas fluorescens].	28.36	409	244	16	47	446	259	627	4e-20	103
rs:WP_017643219	DNA topoisomerase [Streptococcus agalactiae].	26.71	337	210	8	67	398	270	574	4e-20	103
rs:WP_016854570	topoisomerase I [Halomonas smyrnensis].	29.06	406	223	18	70	458	294	651	4e-20	103
rs:WP_016086606	DNA topoisomerase 1 [Bacillus cereus].	24.22	483	301	17	1	457	170	613	4e-20	103
rs:WP_026906107	DNA topoisomerase I [Paucisalibacillus globulus].	24.09	469	286	17	18	457	187	614	4e-20	103
rs:WP_003030274	DNA topoisomerase I [Streptococcus anginosus].	24.53	424	249	13	50	452	237	610	4e-20	103
rs:WP_048350874	DNA topoisomerase I [Pseudomonas psychrophila].	28.61	409	243	16	47	446	259	627	4e-20	103
rs:WP_007545055	DNA topoisomerase I [Haloferax larsenii].	24.70	413	244	13	61	454	276	640	4e-20	103
rs:WP_040450045	DNA topoisomerase I [Hoeflea phototrophica].	26.81	414	245	12	70	452	253	639	4e-20	103
rs:WP_003199646	MULTISPECIES: topoisomerase I [Pseudomonas].	28.12	409	245	16	47	446	259	627	4e-20	103
rs:WP_043042019	DNA topoisomerase I [Pseudomonas fluorescens].	28.12	409	245	16	47	446	259	627	4e-20	103
rs:WP_022446921	DNA topoisomerase [Faecalibacterium sp. CAG:74].	26.81	414	229	17	68	454	252	618	4e-20	103
rs:WP_003042684	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.53	424	249	13	50	452	237	610	4e-20	103
rs:WP_006885830	DNA topoisomerase I [Halosimplex carlsbadense].	25.25	404	253	12	61	454	266	630	4e-20	103
rs:WP_018543479	MULTISPECIES: DNA topoisomerase I [Streptococcus anginosus group].	24.53	424	249	13	50	452	237	610	4e-20	103
rs:WP_031556969	DNA topoisomerase I [Lachnospiraceae bacterium FD2005].	24.20	438	279	12	36	457	215	615	4e-20	103
rs:WP_042456355	DNA topoisomerase I [Bacillus sp. FF4].	25.17	449	265	19	31	457	215	614	4e-20	103
rs:WP_028447198	DNA topoisomerase I [Chitinimonas koreensis].	26.35	425	247	12	50	452	234	614	4e-20	103
tr:A0A0D6BYJ6_9PSED	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.55	392	231	15	68	446	276	627	4e-20	103
rs:WP_028550412	DNA topoisomerase I [Paenibacillus sp. UNC451MF].	26.61	436	250	17	47	457	224	614	4e-20	103
rs:WP_010761353	DNA topoisomerase 1 [Enterococcus haemoperoxidus].	25.40	441	265	18	34	452	211	609	4e-20	103
rs:WP_003034456	DNA topoisomerase I [Streptococcus anginosus].	24.53	424	249	13	50	452	237	610	4e-20	103
rs:WP_044921041	DNA topoisomerase I [Anaerostipes hadrus].	25.47	428	260	13	48	457	227	613	4e-20	103
rs:WP_026234060	DNA topoisomerase I [Thermus oshimai].	27.41	405	218	15	69	454	272	619	4e-20	103
rs:WP_031337825	hypothetical protein, partial [Xylella fastidiosa].	59.46	74	30	0	29	102	35	108	4e-20	95.9
rs:WP_043310071	DNA topoisomerase I [Pseudomonas sp. ML96].	26.41	390	236	12	69	446	276	626	4e-20	103
rs:WP_008329900	DNA topoisomerase I [Maritimibacter alkaliphilus].	28.44	436	241	17	51	454	235	631	4e-20	103
rs:WP_006474388	DNA topoisomerase I [endosymbiont of Tevnia jerichonana].	26.65	409	248	12	61	452	246	619	4e-20	103
rs:WP_035181783	DNA topoisomerase I [Bacillus coagulans].	25.22	456	273	18	26	457	202	613	4e-20	103
rs:WP_019408699	topoisomerase I [Pseudomonas psychrophila].	28.06	392	229	15	68	446	276	627	4e-20	103
rs:WP_017768605	DNA topoisomerase [Streptococcus agalactiae].	27.14	350	215	9	57	398	257	574	4e-20	103
rs:WP_014339360	topoisomerase I [Pseudomonas fluorescens].	28.12	409	245	16	47	446	259	627	4e-20	103
rs:WP_033195612	DNA topoisomerase I, partial [Kushneria aurantia].	29.26	393	227	17	77	458	296	648	4e-20	103
rs:WP_011695783	DNA topoisomerase I [Methanosaeta thermophila].	26.18	401	242	14	69	458	263	620	4e-20	103
rs:WP_012581412	DNA topoisomerase I [Listeria monocytogenes].	25.41	429	247	17	50	452	227	608	4e-20	103
rs:WP_047302981	DNA topoisomerase I [Pseudomonas fluorescens].	27.55	392	231	15	68	446	276	627	4e-20	103
rs:WP_007944143	topoisomerase I [Pseudomonas sp. GM21].	28.50	407	242	16	49	446	261	627	4e-20	103
rs:WP_007685816	DNA topoisomerase I [Sphingobium indicum].	27.42	445	257	16	40	452	219	629	4e-20	103
rs:WP_017689196	DNA topoisomerase I [Paenibacillus sp. PAMC 26794].	25.81	434	260	15	45	457	222	614	4e-20	103
rs:WP_027835164	DNA topoisomerase I [Maritalea myrionectae].	25.31	490	291	17	1	452	172	624	4e-20	103
rs:WP_011110334	DNA topoisomerase I [Bacillus cereus].	25.06	447	269	16	34	457	180	583	4e-20	103
rs:WP_032630415	DNA topoisomerase I [Pseudomonas syringae].	26.60	391	236	13	68	446	275	626	4e-20	103
rs:WP_045638320	DNA topoisomerase I, partial [Peptococcaceae bacterium BRH_c4a].	22.73	440	284	11	36	457	219	620	4e-20	103
rs:WP_040948035	DNA topoisomerase I [Coxiella burnetii].	26.29	426	254	13	48	452	236	622	4e-20	103
rs:XP_005694304	PREDICTED: DNA topoisomerase 3-alpha [Capra hircus].	26.10	433	233	15	60	455	380	762	4e-20	103
rs:WP_039652910	hypothetical protein [Clostridium tyrobutyricum].	24.87	394	262	10	47	427	250	622	4e-20	103
rs:WP_024618391	DNA topoisomerase I [Pseudomonas fluorescens].	28.12	409	245	16	47	446	259	627	4e-20	103
rs:WP_017337559	topoisomerase I [Pseudomonas fluorescens].	28.36	409	244	16	47	446	259	627	4e-20	103
rs:WP_043061269	DNA topoisomerase I [Sphingomonas taxi].	28.17	426	240	16	52	452	233	617	4e-20	103
rs:WP_041958543	DNA topoisomerase I [Sulfurospirillum arsenophilum].	27.64	416	225	17	61	452	238	601	4e-20	103
rs:WP_021127832	DNA topoisomerase I [[Clostridium] sordellii].	23.34	437	274	10	36	454	215	608	4e-20	103
rs:WP_032602860	DNA topoisomerase I, partial [Bacteroides fragilis].	34.63	205	129	4	182	385	2	202	4e-20	98.6
rs:XP_002597412	hypothetical protein BRAFLDRAFT_80591 [Branchiostoma floridae].	25.40	437	254	16	40	453	262	649	4e-20	103
tr:A0A0C7SBB9_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.34	437	274	10	36	454	215	608	4e-20	103
rs:WP_011833511	DNA topoisomerase I [Methanocorpusculum labreanum].	25.34	446	276	15	18	449	216	618	4e-20	103
rs:WP_037029964	DNA topoisomerase [Psychrilyobacter atlanticus].	24.74	380	252	9	61	434	253	604	4e-20	103
rs:WP_045635329	DNA topoisomerase I [Streptococcus mitis].	23.67	431	264	12	40	452	227	610	4e-20	103
rs:WP_007953057	MULTISPECIES: topoisomerase I [Pseudomonas].	27.88	391	229	15	69	446	277	627	4e-20	103
rs:XP_009487964	PREDICTED: DNA topoisomerase 3-alpha [Pelecanus crispus].	26.52	445	262	16	39	456	290	696	4e-20	103
rs:WP_028236271	DNA topoisomerase I [Pseudobutyrivibrio sp. MD2005].	23.86	440	280	13	36	457	213	615	4e-20	103
rs:WP_037332935	DNA topoisomerase I [Salinisphaera hydrothermalis].	26.63	398	233	11	3	377	195	556	5e-20	103
rs:WP_033918373	DNA topoisomerase I [Listeria monocytogenes].	25.06	451	264	18	29	452	205	608	5e-20	103
rs:WP_018604863	DNA topoisomerase I [Pseudomonas sp. CFII68].	28.12	409	245	16	47	446	259	627	5e-20	103
rs:WP_024689275	DNA topoisomerase I [Pseudomonas syringae].	28.40	412	240	16	47	446	259	627	5e-20	103
rs:WP_021785427	MULTISPECIES: topoisomerase I [Pseudomonas putida group].	27.49	411	245	14	47	446	258	626	5e-20	103
tr:G2TJM1_BACCO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.22	456	273	18	26	457	73	484	5e-20	102
tr:A0A0B8PQ94_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAM69255.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAM69255.1};	40.65	123	65	1	200	322	2	116	5e-20	96.7
tr:A0A087RG32_APTFO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.52	445	262	16	39	456	270	676	5e-20	103
tr:K2B533_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.38	431	246	17	46	452	236	623	5e-20	103
rs:WP_041064802	DNA topoisomerase I [Cohnella sp. VKM B-2846].	25.00	432	257	14	50	457	227	615	5e-20	103
rs:WP_017129593	topoisomerase I [Pseudomonas gingeri].	28.61	409	243	16	47	446	259	627	5e-20	103
rs:WP_027335956	DNA topoisomerase I [Halomonas sp. HL-48].	28.28	389	223	14	77	452	296	641	5e-20	103
rs:WP_035596172	MULTISPECIES: DNA topoisomerase I [Halomonas].	29.06	406	223	18	70	458	294	651	5e-20	103
rs:WP_041074035	DNA topoisomerase I [Bacillus sp. OxB-1].	24.37	435	265	17	40	452	217	609	5e-20	103
rs:WP_016780049	topoisomerase I [Pseudomonas fragi].	28.61	409	243	16	47	446	259	627	5e-20	103
rs:WP_006828261	DNA topoisomerase I [Planococcus antarcticus].	25.69	436	256	18	40	452	217	607	5e-20	103
rs:WP_039657745	hypothetical protein [Clostridium tyrobutyricum].	24.87	394	262	10	47	427	250	622	5e-20	103
rs:WP_035028195	DNA topoisomerase I [Carnobacterium mobile].	25.35	426	251	17	50	452	228	609	5e-20	103
rs:WP_012951572	DNA topoisomerase I [Listeria monocytogenes].	25.06	451	264	18	29	452	205	608	5e-20	103
rs:WP_001286971	DNA topoisomerase I [Bacillus cereus].	25.45	444	271	17	34	457	210	613	5e-20	103
rs:WP_001286954	DNA topoisomerase I [Bacillus cereus].	25.45	444	271	17	34	457	210	613	5e-20	103
rs:WP_047970859	DNA topoisomerase I [Bacillus sp. LL01].	25.29	431	262	15	46	457	225	614	5e-20	103
rs:WP_022850531	DNA topoisomerase [Geovibrio sp. L21-Ace-BES].	26.12	425	245	12	47	449	228	605	5e-20	103
rs:WP_015756822	DNA topoisomerase I [Desulfotomaculum acetoxidans].	24.41	467	280	17	22	457	191	615	5e-20	103
rs:WP_003059104	DNA topoisomerase I, partial [Streptococcus dysgalactiae].	24.01	454	278	14	19	452	185	591	5e-20	102
rs:WP_048382328	DNA topoisomerase I [Pseudomonas taetrolens].	27.67	412	251	14	42	446	256	627	5e-20	103
rs:WP_019831106	DNA topoisomerase I [Sphingomonas sp. PR090111-T3T-6A].	27.83	442	243	17	36	452	227	617	5e-20	103
rs:WP_032825101	topoisomerase I, partial [Oenococcus oeni].	32.64	193	120	4	207	397	1	185	5e-20	99.0
rs:WP_013182761	DNA topoisomerase I [Waddlia chondrophila].	25.29	427	259	13	47	454	240	625	5e-20	103
rs:WP_028405688	DNA topoisomerase I [Bacillus sp. J13].	24.59	431	265	14	47	457	224	614	5e-20	103
rs:WP_007392758	DNA topoisomerase I [Megasphaera sp. UPII 135-E].	26.57	414	241	13	58	452	297	666	5e-20	103
tr:F2C637_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.08	436	256	13	40	452	230	613	5e-20	103
rs:WP_003732799	DNA topoisomerase I [Listeria monocytogenes].	25.06	451	264	18	29	452	205	608	5e-20	102
rs:WP_024343926	DNA topoisomerase [Streptococcus equinus].	27.00	337	209	8	67	398	270	574	5e-20	102
rs:WP_000179671	DNA topoisomerase I [Streptococcus oralis].	25.06	415	238	14	60	452	248	611	5e-20	102
tr:A0A091U1D3_9AVES	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.58	444	261	16	40	456	271	676	5e-20	103
rs:WP_025212749	DNA topoisomerase I [Pseudomonas brassicacearum].	28.12	409	245	16	47	446	259	627	5e-20	103
rs:NP_001025807	DNA topoisomerase 3-alpha isoform 1 [Gallus gallus].	25.84	445	265	16	39	456	290	696	5e-20	103
rs:WP_021904113	DNA topoisomerase [Clostridium sp. CAG:81].	24.67	458	285	11	17	457	202	616	5e-20	102
rs:WP_021692710	DNA topoisomerase I [Loktanella cinnabarina].	26.41	462	257	16	41	454	225	651	5e-20	103
rs:WP_013291224	DNA topoisomerase I [Caldicellulosiruptor obsidiansis].	25.36	418	257	12	54	454	230	609	5e-20	102
rs:WP_003024471	DNA topoisomerase I [Streptococcus anginosus].	24.53	424	249	13	50	452	237	610	5e-20	102
rs:WP_037392358	DNA topoisomerase I [Snodgrassella alvi].	24.71	429	251	12	50	452	234	616	5e-20	103
rs:XP_011982803	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Ovis aries musimon].	26.59	425	241	14	60	455	310	692	5e-20	103
rs:WP_009336444	hypothetical protein, partial [Bacillus sp. 2_A_57_CT2].	27.24	246	168	5	42	284	254	491	5e-20	102
rs:WP_041531522	DNA topoisomerase I, partial [Pelobacter carbinolicus].	27.17	427	260	16	45	454	230	622	5e-20	103
rs:WP_034130508	DNA topoisomerase I [Peptococcaceae bacterium BICA1-8].	26.57	429	257	12	48	458	226	614	5e-20	102
rs:WP_037523331	DNA topoisomerase I [Sphingomonas wittichii].	29.10	409	220	16	71	452	252	617	5e-20	103
rs:WP_012498988	DNA topoisomerase I [Chloroherpeton thalassium].	26.80	459	254	18	32	454	226	638	6e-20	103
rs:WP_046720801	DNA topoisomerase I [Bacillus coagulans].	25.22	456	273	18	26	457	202	613	6e-20	102
tr:C3FP15_BACTB	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.55	444	265	15	34	452	203	601	6e-20	102
rs:WP_022525855	topoisomerase IA [Streptococcus anginosus].	24.53	424	249	13	50	452	237	610	6e-20	102
rs:WP_002355993	DNA topoisomerase, partial [Enterococcus faecium].	32.56	215	133	5	93	304	8	213	6e-20	98.2
rs:WP_027270824	DNA topoisomerase I [Legionella sainthelensi].	27.31	432	245	16	46	452	234	621	6e-20	102
rs:WP_001286953	DNA topoisomerase I [Bacillus cereus].	25.45	444	271	17	34	457	210	613	6e-20	102
rs:WP_013458656	DNA topoisomerase I [Oceanithermus profundus].	25.75	431	249	13	41	454	227	603	6e-20	103
tr:K1QMX0_CRAGI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.39	445	264	14	40	456	207	611	6e-20	103
rs:WP_005988628	DNA topoisomerase I [Desulfovibrio africanus].	25.47	428	259	12	47	450	225	616	6e-20	102
rs:WP_039125636	DNA topoisomerase I [Francisella guangzhouensis].	26.93	401	243	13	70	452	256	624	6e-20	102
rs:WP_007128765	DNA topoisomerase I [Paenibacillus lactis].	24.59	431	265	14	47	457	224	614	6e-20	102
tr:C2PIZ8_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.45	444	271	17	34	457	203	606	6e-20	102
rs:WP_032991710	DNA topoisomerase III, partial [Cronobacter dublinensis].	45.54	101	55	0	36	136	215	315	6e-20	99.8
rs:WP_017551515	DNA topoisomerase I [Bacillus coagulans].	25.22	456	273	18	26	457	202	613	6e-20	102
rs:WP_012111753	DNA topoisomerase I [Parvibaculum lavamentivorans].	25.23	440	267	12	43	452	226	633	6e-20	103
rs:WP_021490989	topoisomerase I [Pseudomonas fluorescens].	28.12	409	245	16	47	446	259	627	6e-20	103
rs:XP_011982805	PREDICTED: DNA topoisomerase 3-alpha isoform X4 [Ovis aries musimon].	26.59	425	241	14	60	455	147	529	6e-20	103
rs:WP_030139950	DNA topoisomerase I [Pseudomonas fluorescens].	28.12	409	245	16	47	446	259	627	6e-20	103
rs:WP_014612281	DNA topoisomerase I [Streptococcus dysgalactiae].	24.01	454	278	14	19	452	218	624	6e-20	102
rs:WP_032909719	DNA topoisomerase I [Streptococcus sanguinis].	24.08	436	256	13	40	452	227	610	6e-20	102
rs:WP_042356248	DNA topoisomerase I [Bacillus sp. MT2].	25.92	436	246	18	50	457	228	614	6e-20	102
rs:WP_002407054	DNA topoisomerase I [Enterococcus faecalis].	24.60	439	271	17	34	452	211	609	6e-20	102
rs:WP_047389854	DNA topoisomerase I [Carnobacterium sp. ZWU0011].	25.67	413	254	12	56	452	234	609	6e-20	102
tr:C2YVB5_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.45	444	271	17	34	457	203	606	6e-20	102
rs:WP_041725675	DNA topoisomerase I [Caldicellulosiruptor lactoaceticus].	25.00	420	256	13	54	454	231	610	6e-20	102
tr:F1P1F3_CHICK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.84	445	265	16	39	456	290	696	6e-20	103
rs:WP_010449613	topoisomerase I [Pseudomonas fuscovaginae].	27.43	412	252	14	42	446	256	627	6e-20	103
rs:WP_015017017	DNA topoisomerase I [Streptococcus dysgalactiae].	24.01	454	278	14	19	452	228	634	6e-20	102
tr:T0ZCB8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD42728.1};	27.55	432	260	15	35	453	240	631	6e-20	102
tr:F8LFA1_9CHLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.06	427	260	12	47	454	240	625	6e-20	102
rs:WP_009754430	DNA topoisomerase I [Streptococcus sp. oral taxon 056].	24.08	436	256	13	40	452	227	610	6e-20	102
rs:XP_009284732	PREDICTED: DNA topoisomerase 3-alpha [Aptenodytes forsteri].	26.52	445	262	16	39	456	290	696	6e-20	103
rs:XP_011982804	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Ovis aries musimon].	26.59	425	241	14	60	455	227	609	6e-20	103
tr:Q3A7H8_PELCD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.17	427	260	16	45	454	230	622	6e-20	102
rs:WP_026375035	DNA topoisomerase I [Aestuariibacter salexigens].	27.95	390	224	16	71	446	284	630	6e-20	103
rs:XP_009807307	PREDICTED: DNA topoisomerase 3-alpha [Gavia stellata].	26.29	445	263	16	39	456	261	667	6e-20	103
tr:A0A093F4L3_GAVST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.29	445	263	16	39	456	268	674	6e-20	103
rs:WP_006922415	DNA topoisomerase I [Desulfovibrio magneticus].	26.68	416	245	13	54	452	232	604	6e-20	102
rs:WP_014092677	DNA topoisomerase I [Listeria ivanovii].	25.41	429	247	17	50	452	227	608	6e-20	102
rs:WP_000179622	DNA topoisomerase I [Streptococcus oralis].	25.06	415	238	14	60	452	248	611	6e-20	102
rs:WP_022115579	DNA topoisomerase [Clostridium sp. CAG:524].	27.38	420	245	15	47	450	221	596	6e-20	102
tr:A0A091PZ42_LEPDC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.52	445	262	16	39	456	228	634	6e-20	103
rs:WP_010184446	DNA topoisomerase I [Sphingomonas sp. PAMC 26605].	28.54	424	241	15	52	452	233	617	6e-20	102
rs:WP_019369891	DNA topoisomerase I [Sphingomonas sp. ATCC 31555].	27.59	435	249	15	43	452	224	617	6e-20	102
rs:WP_006531800	DNA topoisomerase [Streptococcus infantarius].	27.81	338	205	11	67	398	270	574	6e-20	102
rs:WP_001286955	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.55	444	265	15	34	452	210	608	6e-20	102
tr:X1KW99_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_C00401 {ECO:0000313|EMBL:GAH97920.1}; Flags: Fragment;	25.06	387	228	12	85	453	17	359	6e-20	101
rs:WP_017895115	hypothetical protein [Clostridium tyrobutyricum].	24.87	394	262	10	47	427	250	622	6e-20	102
rs:XP_009946177	PREDICTED: DNA topoisomerase 3-alpha, partial [Leptosomus discolor].	26.52	445	262	16	39	456	228	634	6e-20	102
rs:WP_035188460	DNA topoisomerase I [Bacillus coagulans].	25.22	456	273	18	26	457	202	613	7e-20	102
rs:WP_010744647	DNA topoisomerase 1 [Enterococcus raffinosus].	23.81	441	282	12	34	457	211	614	7e-20	102
rs:WP_007516861	DNA topoisomerase I [Streptococcus tigurinus].	25.06	415	238	14	60	452	248	611	7e-20	102
rs:WP_004042619	DNA topoisomerase I, partial [Lactobacillus sp. ASF360].	25.11	442	271	13	34	457	222	621	7e-20	102
rs:WP_017184447	DNA topoisomerase I [Sphingobium xenophagum].	26.03	484	289	16	1	452	171	617	7e-20	102
rs:WP_043917610	DNA topoisomerase I [Jannaschia aquimarina].	27.64	474	249	19	41	454	225	664	7e-20	102
rs:WP_015477970	DNA topoisomerase I subunit omega [Pseudomonas denitrificans].	27.45	408	249	14	47	446	257	625	7e-20	102
rs:WP_028387468	DNA topoisomerase I [Legionella geestiana].	27.51	429	249	13	45	452	233	620	7e-20	102
rs:WP_025068382	DNA topoisomerase, partial [Prevotella denticola].	28.73	268	175	6	160	426	26	278	7e-20	100
rs:WP_012766956	DNA topoisomerase I [Streptococcus dysgalactiae].	24.01	454	278	14	19	452	218	624	7e-20	102
tr:A0A091UJS7_PHORB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.52	445	262	16	39	456	270	676	7e-20	102
tr:W1TZD8_STRAP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.53	424	249	13	50	452	240	613	7e-20	102
tr:G2PUY5_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	420	256	13	54	454	230	609	7e-20	102
rs:WP_021668982	DNA topoisomerase, partial [Prevotella disiens].	33.92	227	145	4	160	384	28	251	7e-20	99.4
rs:WP_045211687	DNA topoisomerase I [Pseudomonas sp. 21].	26.85	391	235	12	68	446	274	625	7e-20	102
rs:XP_009666303	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Struthio camelus australis].	26.52	445	262	16	39	456	212	618	7e-20	102
tr:L9PZY6_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELX68407.1};	30.40	227	153	4	160	384	2	225	7e-20	100
rs:WP_003062355	DNA topoisomerase I [Streptococcus dysgalactiae].	24.01	454	278	14	19	452	218	624	7e-20	102
rs:WP_008896716	DNA topoisomerase I [Haloterrigena salina].	23.76	425	276	13	40	454	246	632	7e-20	102
rs:WP_021787017	hypothetical protein, partial [Ferroplasma sp. Type II].	25.00	428	263	14	38	453	233	614	7e-20	102
rs:WP_007994702	topoisomerase I [Pseudomonas sp. GM49].	28.36	409	244	16	47	446	259	627	7e-20	102
rs:WP_026858406	DNA topoisomerase I [Jeotgalicoccus psychrophilus].	25.65	425	255	17	47	452	225	607	7e-20	102
tr:A0A0A0M4X3_9LACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.46	213	134	6	57	266	247	450	7e-20	102
rs:WP_044020637	DNA topoisomerase I [Streptococcus sp. VT 162].	24.57	411	245	12	60	452	248	611	7e-20	102
rs:WP_008023008	topoisomerase I [Pseudomonas sp. GM55].	28.36	409	244	16	47	446	259	627	7e-20	102
rs:NP_001085699	topoisomerase (DNA) III alpha [Xenopus laevis].	26.04	457	267	17	27	452	277	693	7e-20	102
rs:WP_011247121	DNA topoisomerase I [Bacillus clausii].	25.59	426	256	14	47	452	224	608	7e-20	102
rs:WP_014292698	topoisomerase I [Oceanimonas sp. GK1].	27.19	434	252	15	38	452	253	641	7e-20	102
rs:WP_009821529	DNA topoisomerase I [Sphingomonas sp. SKA58].	27.95	440	249	17	40	452	219	617	7e-20	102
rs:WP_037021839	DNA topoisomerase I [Pseudomonas sp. 20_BN].	26.37	402	240	13	68	452	272	634	7e-20	102
rs:WP_021049991	Topoisomerase IA [Haloquadratum walsbyi].	23.17	423	270	12	44	454	269	648	7e-20	102
rs:WP_031437885	DNA topoisomerase I [Methylobacter tundripaludum].	28.00	425	244	17	50	452	238	622	7e-20	102
rs:WP_011307105	DNA topoisomerase [Methanosarcina barkeri].	26.52	445	269	17	31	454	255	662	7e-20	102
rs:WP_013438822	DNA topoisomerase III [Edwardsiella tarda].	29.84	248	168	5	31	277	240	482	7e-20	102
rs:WP_006739580	DNA topoisomerase [Streptococcus urinalis].	27.05	366	226	13	48	405	251	583	7e-20	102
rs:WP_014865375	DNA topoisomerase I [Natrinema sp. J7-2].	24.88	426	270	14	40	454	246	632	7e-20	102
rs:WP_018712559	hypothetical protein [Campylobacter ureolyticus].	26.42	424	242	14	47	450	224	597	7e-20	102
rs:WP_027589307	DNA topoisomerase I [Pseudomonas sp. RL].	27.01	411	226	15	68	452	273	635	7e-20	102
rs:WP_042753922	DNA topoisomerase I [Streptococcus anginosus].	24.53	424	249	13	50	452	237	610	8e-20	102
rs:XP_010814336	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Bos taurus].	26.42	424	241	14	61	455	311	692	8e-20	102
rs:WP_019376482	DNA topoisomerase I [Virgibacillus halodenitrificans].	26.16	432	251	17	50	457	227	614	8e-20	102
rs:WP_014149842	DNA topoisomerase I [Methylomicrobium alcaliphilum].	26.19	443	265	15	31	452	221	622	8e-20	102
tr:Q702B0_9CREN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.09	460	260	17	18	446	236	646	8e-20	102
rs:WP_017554457	DNA topoisomerase I [Bacillus coagulans].	25.22	456	273	18	26	457	202	613	8e-20	102
rs:WP_039605753	DNA topoisomerase I [Pseudomonas tuomuerensis].	27.01	411	226	15	68	452	273	635	8e-20	102
rs:WP_030127251	DNA topoisomerase I [Streptococcus pyogenes].	24.01	454	278	14	19	452	218	624	8e-20	102
tr:U6PAL2_HAECO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.62	447	247	19	39	457	300	693	8e-20	102
rs:WP_022994440	MULTISPECIES: topoisomerase I [Alcanivorax].	26.33	395	240	13	65	446	285	641	8e-20	102
rs:WP_048168258	DNA topoisomerase, partial [Methanosarcina thermophila].	26.73	449	263	19	31	454	239	646	8e-20	102
rs:XP_006272770	PREDICTED: DNA topoisomerase 3-alpha [Alligator mississippiensis].	25.95	447	262	16	39	456	205	611	8e-20	102
rs:WP_039020056	DNA topoisomerase I [Halocynthiibacter namhaensis].	27.85	438	251	16	44	454	228	627	8e-20	102
rs:WP_014105207	DNA topoisomerase I [Komagataeibacter medellinensis].	26.09	414	245	14	70	452	254	637	8e-20	102
rs:WP_039562051	DNA topoisomerase I [Serpens flexibilis].	27.01	411	226	15	68	452	273	635	8e-20	102
rs:WP_036651426	DNA topoisomerase I [Paenibacillus pini].	25.40	437	266	13	41	457	218	614	8e-20	102
rs:WP_019052099	DNA topoisomerase I [Sphingobium xenophagum].	26.03	484	289	16	1	452	171	617	8e-20	102
rs:WP_001286964	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	24.22	483	301	17	1	457	170	613	8e-20	102
rs:WP_001286963	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.22	483	301	17	1	457	170	613	8e-20	102
rs:WP_033617385	topoisomerase I, partial [Lactobacillus plantarum].	31.35	252	151	8	24	266	63	301	8e-20	99.4
rs:XP_009666302	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Struthio camelus australis].	26.52	445	262	16	39	456	290	696	8e-20	102
tr:F1MGY1_BOVIN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.42	424	241	14	61	455	311	692	8e-20	102
rs:XP_004502963	PREDICTED: DNA topoisomerase 3-alpha [Cicer arietinum].	25.00	468	278	17	18	451	241	669	8e-20	102
rs:WP_011184520	DNA topoisomerase I [Streptococcus pyogenes].	24.01	454	278	14	19	452	218	624	8e-20	102
rs:WP_040611837	DNA topoisomerase I [Roseomonas cervicalis].	26.40	447	267	14	41	454	225	642	8e-20	102
rs:NP_001071443	DNA topoisomerase 3-alpha [Bos taurus].	26.42	424	241	14	61	455	311	692	8e-20	102
rs:WP_011878312	DNA topoisomerase I [Desulfotomaculum reducens].	25.40	433	256	15	48	457	226	614	9e-20	102
tr:D5TVA4_BACT1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.22	483	301	17	1	457	129	572	9e-20	102
rs:WP_012050010	DNA topoisomerase I [Sphingomonas wittichii].	28.25	439	244	16	47	452	228	628	9e-20	102
rs:WP_037012660	DNA topoisomerase I [Pseudomonas nitroreducens].	26.85	391	235	12	68	446	274	625	9e-20	102
rs:WP_013859077	DNA topoisomerase I [Bacillus coagulans].	25.22	456	273	19	26	457	202	613	9e-20	102
tr:C2T4T6_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.22	483	301	17	1	457	140	583	9e-20	102
rs:WP_010965091	DNA topoisomerase I [Clostridium acetobutylicum].	26.40	428	250	15	48	454	227	610	9e-20	102
rs:WP_023610295	DNA topoisomerase I [Streptococcus pyogenes].	24.01	454	278	14	19	452	218	624	9e-20	102
rs:WP_036767626	DNA topoisomerase I, partial [Peptostreptococcaceae bacterium VA2].	22.90	428	266	12	46	454	225	607	9e-20	102
rs:WP_038415193	DNA topoisomerase I [Bacillus thuringiensis].	24.22	483	301	17	1	457	170	613	9e-20	102
rs:WP_002995012	DNA topoisomerase I [Streptococcus pyogenes].	24.01	454	278	14	19	452	218	624	9e-20	102
rs:WP_040304038	DNA topoisomerase I, partial [Campylobacter gracilis].	25.23	432	245	17	43	450	220	597	9e-20	102
rs:WP_024766855	DNA topoisomerase I [Pseudomonas nitroreducens].	26.85	391	235	12	68	446	274	625	9e-20	102
rs:WP_047842473	DNA topoisomerase I [Paenibacillus sp. VT-400].	25.17	433	264	14	45	457	222	614	9e-20	102
rs:WP_006664395	DNA topoisomerase I [Natrialba aegyptia].	24.75	404	257	12	60	454	267	632	9e-20	102
rs:WP_013172665	DNA topoisomerase I [[Bacillus] selenitireducens].	25.17	437	268	17	35	452	211	607	9e-20	102
tr:A0A093D0I4_TAUER	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.23	446	262	17	39	456	229	635	9e-20	102
rs:WP_036721378	DNA topoisomerase I [Paracoccus sphaerophysae].	26.77	437	262	16	41	454	222	623	9e-20	102
rs:WP_014643263	DNA topoisomerase I [Halobacillus halophilus].	25.54	419	257	12	56	457	233	613	9e-20	102
rs:WP_029994545	DNA topoisomerase I [Sphingomonas sp. YL-JM2C].	28.25	439	244	16	47	452	228	628	9e-20	102
tr:K8BYZ7_9ENTR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CCJ97843.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CCJ97843.1};	40.48	126	75	0	260	385	2	127	9e-20	96.7
tr:D5RQA4_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.17	447	268	14	41	454	238	655	9e-20	102
rs:WP_023026804	DNA topoisomerase I [Streptococcus sp. I-G2].	24.47	421	255	13	49	452	237	611	9e-20	102
tr:H2A926_STRMD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.41	337	211	8	67	398	270	574	9e-20	102
rs:WP_044405059	DNA topoisomerase I [Pseudomonas sp. FeS53a].	26.96	408	251	13	47	446	258	626	9e-20	102
rs:WP_006927518	DNA topoisomerase I [Caldithrix abyssi].	23.66	465	255	15	54	454	236	664	1e-19	102
rs:WP_025329888	DNA topoisomerase I [Snodgrassella alvi].	24.54	436	257	12	43	452	227	616	1e-19	102
rs:XP_011100133	PREDICTED: DNA topoisomerase 3-alpha [Sesamum indicum].	26.28	468	260	19	24	452	245	666	1e-19	102
rs:WP_038704262	DNA topoisomerase I [Planococcus sp. PAMC 21323].	24.07	482	292	18	1	452	170	607	1e-19	102
tr:A0A091ISF3_9AVES	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.52	445	262	16	39	456	270	676	1e-19	102
rs:WP_018250549	DNA topoisomerase I [Sphingomonas melonis].	28.75	407	224	16	71	452	252	617	1e-19	102
tr:A0A093H5G5_STRCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.52	445	262	16	39	456	270	676	1e-19	102
tr:E4S8P0_CALKI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	420	256	13	54	454	230	609	1e-19	102
rs:WP_029300089	DNA topoisomerase I [Pseudomonas fluorescens].	28.12	409	245	16	47	446	259	627	1e-19	102
rs:WP_027978427	DNA topoisomerase I [gamma proteobacterium L18].	27.83	406	246	14	49	446	260	626	1e-19	102
rs:WP_024362045	MULTISPECIES: DNA topoisomerase I [Lysinibacillus].	26.09	437	255	19	40	452	217	609	1e-19	102
rs:WP_009924617	DNA topoisomerase I [Listeria monocytogenes].	25.17	429	248	17	50	452	227	608	1e-19	102
rs:WP_043065995	DNA topoisomerase I [Aneurinibacillus migulanus].	25.41	429	257	15	50	457	227	613	1e-19	102
rs:WP_035168545	MULTISPECIES: DNA topoisomerase I [Caldicellulosiruptor].	25.00	420	256	13	54	454	231	610	1e-19	102
rs:WP_006959504	DNA topoisomerase I [Sphingobium japonicum].	26.24	484	288	16	1	452	171	617	1e-19	102
tr:S6EZC3_LACLL	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.25	345	208	11	66	404	293	600	1e-19	102
rs:WP_003632876	DNA topoisomerase I [Legionella longbeachae].	26.91	431	248	15	46	452	234	621	1e-19	102
rs:WP_024418977	DNA topoisomerase [Streptococcus suis].	28.49	344	202	11	61	396	264	571	1e-19	102
rs:WP_000179675	DNA topoisomerase I [Streptococcus oralis].	24.57	411	245	12	60	452	248	611	1e-19	102
rs:WP_000179670	DNA topoisomerase I [Streptococcus oralis].	24.57	411	245	12	60	452	248	611	1e-19	102
rs:XP_009647736	PREDICTED: DNA topoisomerase 3-alpha [Egretta garzetta].	26.52	445	262	16	39	456	290	696	1e-19	102
rs:WP_015695732	DNA topoisomerase [Streptococcus infantarius].	26.41	337	211	8	67	398	270	574	1e-19	102
rs:WP_003738814	DNA topoisomerase I [Listeria monocytogenes].	25.17	429	248	17	50	452	227	608	1e-19	102
rs:WP_036278948	DNA topoisomerase I [Microbacterium sp. CH12i].	32.28	316	167	14	51	356	267	545	1e-19	102
rs:WP_003727517	DNA topoisomerase I [Listeria monocytogenes].	25.17	429	248	17	50	452	227	608	1e-19	102
tr:C2N519_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.22	483	301	17	1	457	140	583	1e-19	102
rs:WP_035162822	DNA topoisomerase I [Caloranaerobacter azorensis].	25.23	428	262	11	47	457	228	614	1e-19	102
rs:WP_021291589	MULTISPECIES: DNA topoisomerase I [Virgibacillus].	24.15	468	287	16	18	457	187	614	1e-19	102
rs:WP_031666351	DNA topoisomerase I [Listeria monocytogenes].	25.17	429	248	17	50	452	227	608	1e-19	102
rs:XP_009886830	PREDICTED: DNA topoisomerase 3-alpha [Charadrius vociferus].	26.29	445	263	16	39	456	290	696	1e-19	102
rs:WP_017124206	DNA topoisomerase I [Pseudomonas gingeri].	25.44	397	254	11	74	459	260	625	1e-19	102
rs:WP_015849264	endonuclease [Thermococcus sibiricus].	27.74	393	201	15	112	457	828	1184	1e-19	102
tr:C2P2H6_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.22	483	301	17	1	457	140	583	1e-19	102
rs:WP_032242256	DNA topoisomerase III, partial [Escherichia coli].	35.95	153	94	1	37	189	245	393	1e-19	100
rs:WP_047444294	hypothetical protein [Alistipes sp. ZOR0009].	26.86	309	184	7	51	354	239	510	1e-19	102
rs:XP_010196093	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha [Colius striatus].	26.71	423	246	15	60	456	308	692	1e-19	102
rs:WP_044337412	DNA topoisomerase I [Bacillus aquimaris].	24.01	454	283	15	25	457	201	613	1e-19	102
rs:WP_027611447	DNA topoisomerase I [Pseudomonas sp. URIL14HWK12:I6].	27.62	391	230	15	69	446	277	627	1e-19	102
rs:WP_027900629	DNA topoisomerase I [Pseudomonas syringae].	26.85	391	235	13	68	446	275	626	1e-19	102
rs:WP_010785477	DNA topoisomerase 1 [Enterococcus faecalis].	24.83	439	270	17	34	452	211	609	1e-19	102
rs:WP_031674614	DNA topoisomerase I [Listeria monocytogenes].	25.17	429	248	17	50	452	227	608	1e-19	102
rs:WP_026574870	DNA topoisomerase I [Bacillus sp. UNC438CL73TsuS30].	24.88	434	253	15	50	457	228	614	1e-19	102
rs:WP_032946838	hypothetical protein [Lactococcus lactis].	27.25	345	208	11	66	404	289	596	1e-19	101
rs:WP_041964483	DNA topoisomerase I [Bacillus selenatarsenatis].	25.88	425	250	16	50	452	227	608	1e-19	102
rs:WP_032464379	DNA topoisomerase I [Streptococcus pyogenes].	24.01	454	278	14	19	452	218	624	1e-19	102
rs:WP_048368712	DNA topoisomerase I [Pseudomonas sp. DSM 29165].	27.43	412	252	14	42	446	256	627	1e-19	102
rs:XP_010138219	PREDICTED: DNA topoisomerase 3-alpha, partial [Buceros rhinoceros silvestris].	26.29	445	263	16	39	456	228	634	1e-19	102
rs:WP_022441506	DNA topoisomerase [Clostridium sp. CAG:768].	22.34	479	302	12	1	450	185	622	1e-19	102
rs:WP_017977323	DNA topoisomerase I [Sphingomonas melonis].	28.75	407	224	16	71	452	252	617	1e-19	102
rs:WP_048389321	DNA topoisomerase I [Pseudomonas sp. DSM 28141].	27.43	412	252	14	42	446	256	627	1e-19	102
rs:WP_045162551	DNA topoisomerase I [Pseudomonas stutzeri].	26.12	402	241	13	68	452	273	635	1e-19	102
tr:A0A075JPQ3_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AIF42093.1};	28.30	265	176	6	193	454	1	254	1e-19	99.0
tr:A0A090SJ58_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL27765.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL27765.1};	28.00	250	151	7	214	449	2	236	1e-19	98.2
rs:XP_009988506	PREDICTED: DNA topoisomerase 3-alpha, partial [Tauraco erythrolophus].	26.23	446	262	17	39	456	228	634	1e-19	102
rs:WP_036609379	MULTISPECIES: DNA topoisomerase I [Paenibacillus].	25.17	429	261	14	49	457	226	614	1e-19	102
rs:WP_016427618	DNA topoisomerase 1 [Paenisporosarcina sp. HGH0030].	24.88	434	263	16	40	452	217	608	1e-19	102
rs:WP_017246024	topoisomerase I [Pseudomonas stutzeri].	25.82	426	258	14	42	452	253	635	1e-19	102
rs:WP_010931749	DNA topoisomerase I [Chlorobaculum tepidum].	25.00	436	253	15	47	450	235	628	1e-19	102
rs:WP_031659876	DNA topoisomerase I [Listeria monocytogenes].	25.17	429	248	17	50	452	227	608	1e-19	102
rs:WP_034156438	DNA topoisomerase I [Pseudomonas fluorescens].	27.87	409	246	16	47	446	259	627	1e-19	102
rs:WP_017365594	DNA topoisomerase I [Methylococcus capsulatus].	28.50	414	216	17	70	452	257	621	1e-19	102
rs:WP_046615846	DNA topoisomerase I [Pseudomonas putida].	27.49	411	245	14	47	446	258	626	1e-19	102
rs:WP_018578499	DNA topoisomerase I [Legionella shakespearei].	27.48	444	256	16	27	452	225	620	1e-19	102
rs:WP_035486060	DNA topoisomerase I, partial [Alicyclobacillus contaminans].	24.89	446	268	14	36	457	213	615	1e-19	102
rs:WP_024823998	DNA topoisomerase I [Desulfovibrio magneticus].	26.25	419	243	14	54	452	232	604	1e-19	102
rs:WP_026438723	DNA topoisomerase I [Acidocella facilis].	28.03	421	246	15	60	452	244	635	1e-19	102
tr:A0A060T6F5_BLAAD	SubName: Full=ARAD1B11726p {ECO:0000313|EMBL:CDP36384.1};	26.55	388	232	11	39	408	258	610	1e-19	101
rs:WP_047254498	DNA topoisomerase [Enterococcus cecorum].	26.32	323	202	9	70	385	283	576	1e-19	102
gp:AP010969_875	DNA topoisomerase I [Streptococcus intermedius JTH08]	24.58	419	255	12	50	452	240	613	1e-19	102
rs:WP_046163817	DNA topoisomerase I [Pseudomonas sp. 10B238].	26.49	419	256	14	47	452	256	635	1e-19	102
tr:E5VI15_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.47	424	261	13	50	457	229	613	1e-19	102
rs:WP_003069065	DNA topoisomerase I [Streptococcus intermedius].	23.97	438	259	14	39	452	208	595	1e-19	102
rs:WP_001286960	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.22	483	301	17	1	457	170	613	1e-19	102
rs:WP_005851683	DNA topoisomerase I [Sulfitobacter sp. EE-36].	27.78	432	253	17	47	454	231	627	1e-19	102
rs:WP_019935728	topoisomerase I [Oceanimonas smirnovii].	27.55	432	253	14	38	452	253	641	1e-19	102
rs:WP_042722664	DNA topoisomerase I, partial [Flavobacterium sp. B17].	25.26	285	191	5	20	304	240	502	1e-19	101
rs:WP_014124944	DNA topoisomerase I [Tetragenococcus halophilus].	24.72	449	268	15	34	457	211	614	1e-19	102
tr:A0A0C7GC68_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.69	439	270	12	36	454	215	608	1e-19	102
rs:WP_003829064	DNA topoisomerase I [Citrobacter freundii].	26.73	434	255	18	38	459	215	597	1e-19	101
rs:WP_045763428	DNA topoisomerase I [Streptococcus mitis].	25.48	416	235	15	60	452	248	611	1e-19	102
tr:E7S6H7_STRAG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.11	337	212	8	67	398	277	581	1e-19	101
rs:WP_033919532	DNA topoisomerase I [Sphingomonas sp. 37zxx].	28.10	420	248	13	52	452	233	617	1e-19	102
rs:WP_013778279	DNA topoisomerase I [Tepidanaerobacter acetatoxydans].	24.34	456	262	13	47	450	224	648	1e-19	102
rs:WP_037608064	DNA topoisomerase [Streptococcus sp. CM7].	26.53	343	209	9	67	401	269	576	1e-19	101
rs:WP_002691935	DNA topoisomerase I [Beggiatoa alba].	26.57	429	248	16	48	452	236	621	1e-19	102
rs:WP_011361129	DNA topoisomerase I [Chlorobium chlorochromatii].	26.65	409	238	14	69	451	257	629	1e-19	102
tr:A0A091R088_9GRUI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.12	448	260	16	39	456	183	589	1e-19	102
rs:WP_042712403	DNA topoisomerase III, partial [Klebsiella cf. planticola B43].	46.53	101	54	0	36	136	251	351	1e-19	99.4
rs:WP_010282476	DNA topoisomerase I [Bacillus timonensis].	25.06	439	264	16	41	457	218	613	1e-19	101
rs:WP_045992673	DNA topoisomerase I [Halomonas sp. S2151].	28.57	406	225	18	70	458	291	648	1e-19	102
rs:WP_014994167	topoisomerase I [Alcanivorax dieselolei].	26.33	395	240	13	65	446	285	641	1e-19	102
rs:WP_010713378	DNA topoisomerase 1 [Enterococcus faecalis].	24.83	439	270	17	34	452	211	609	1e-19	101
rs:WP_041787144	DNA topoisomerase [Streptococcus constellatus].	26.53	343	209	9	67	401	269	576	1e-19	101
rs:WP_034335979	hypothetical protein, partial [Deinococcus misasensis].	27.91	369	217	13	35	387	229	564	1e-19	101
rs:WP_000179666	DNA topoisomerase I [Streptococcus oralis].	25.06	415	238	14	60	452	248	611	1e-19	101
rs:WP_034629666	DNA topoisomerase I [Bacillus okhensis].	24.12	427	258	13	49	452	226	609	1e-19	101
rs:WP_029141585	DNA topoisomerase I [Bacillus coagulans].	25.22	456	273	19	26	457	202	613	1e-19	101
rs:WP_026559364	DNA topoisomerase I [Bacillus sp. J37].	24.05	449	271	17	34	457	210	613	1e-19	101
rs:WP_022689888	DNA topoisomerase I [Sphingomonas-like bacterium B12].	27.09	491	275	19	1	452	171	617	1e-19	102
rs:WP_038805367	DNA topoisomerase I [Streptococcus dentisani].	24.57	411	245	12	60	452	248	611	1e-19	101
rs:WP_015269531	MULTISPECIES: DNA topoisomerase I subunit omega [Pseudomonas].	27.49	411	245	14	47	446	258	626	1e-19	102
rs:WP_043872469	DNA topoisomerase I [Legionella massiliensis].	27.88	434	242	18	45	452	233	621	1e-19	101
rs:WP_015791283	DNA topoisomerase I [Methanocaldococcus fervens].	25.81	465	275	20	18	459	216	633	1e-19	101
rs:WP_004883804	DNA topoisomerase I subunit omega [Pseudomonas viridiflava].	27.70	408	248	14	47	446	259	627	1e-19	102
rs:WP_006649229	DNA topoisomerase I [Haloterrigena thermotolerans].	23.80	437	278	14	31	454	255	649	1e-19	102
rs:WP_046143534	MULTISPECIES: DNA topoisomerase I [Devosia].	27.36	435	250	16	47	452	230	627	1e-19	102
tr:A0A0A0AQJ5_CHAVO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.29	445	263	16	39	456	270	676	1e-19	102
rs:WP_034096476	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	28.12	409	245	16	47	446	259	627	1e-19	102
rs:WP_032912452	DNA topoisomerase I [Streptococcus sanguinis].	23.85	436	257	13	40	452	227	610	1e-19	101
rs:WP_046510821	DNA topoisomerase I [Salinicoccus sp. SV-16].	22.92	480	300	16	1	452	169	606	1e-19	101
rs:WP_014108707	topoisomerase I [Glaciecola nitratireducens].	25.89	421	250	15	42	446	256	630	1e-19	102
rs:WP_011541512	DNA topoisomerase I [Sphingopyxis alaskensis].	27.76	407	228	14	71	452	252	617	1e-19	102
rs:WP_017906684	topoisomerase I [Pseudomonas fuscovaginae].	27.18	412	253	14	42	446	256	627	1e-19	102
rs:WP_044563142	DNA topoisomerase [Streptococcus macedonicus].	26.41	337	211	8	67	398	281	585	1e-19	101
tr:J9J536_9SPIT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EJY84543.1};	25.00	388	238	13	26	397	202	552	1e-19	102
rs:WP_003076379	DNA topoisomerase I [Streptococcus intermedius].	24.58	419	255	12	50	452	237	610	1e-19	101
rs:WP_028967690	DNA topoisomerase I [Sphingomonas phyllosphaerae].	28.64	426	248	15	48	452	227	617	1e-19	102
rs:WP_018917300	topoisomerase I [Halomonas zhanjiangensis].	27.45	419	240	16	51	452	270	641	1e-19	102
rs:WP_038705745	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	27.87	409	246	15	47	446	258	626	1e-19	102
tr:D1NGU7_HAEIF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	43.00	100	57	0	36	135	57	156	1e-19	95.5
gp:CP003859_761	DNA topoisomerase III [Streptococcus constellatus subsp. pharyngis C1050]	26.53	343	209	9	67	401	273	580	1e-19	101
tr:X0ZH22_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_C00245 {ECO:0000313|EMBL:GAG68624.1};	24.28	416	252	13	56	453	65	435	1e-19	100
rs:WP_000179677	DNA topoisomerase I [Streptococcus sp. SK140].	25.37	406	236	13	66	452	254	611	1e-19	101
rs:WP_031834544	DNA topoisomerase III, partial [Staphylococcus aureus].	27.20	250	160	4	35	278	227	460	1e-19	100
rs:WP_034580483	DNA topoisomerase I [Clostridium acetobutylicum].	26.40	428	250	15	48	454	227	610	1e-19	101
rs:WP_021700517	DNA topoisomerase I [Pseudomonas alcaligenes].	26.47	408	253	13	47	446	258	626	1e-19	101
rs:WP_026962107	DNA topoisomerase I [Alicyclobacillus herbarius].	24.34	489	295	14	1	457	170	615	1e-19	101
rs:XP_010180235	PREDICTED: DNA topoisomerase 3-alpha, partial [Mesitornis unicolor].	26.12	448	260	16	39	456	201	607	1e-19	102
rs:WP_048121617	DNA topoisomerase [Methanosarcina vacuolata].	26.52	445	269	17	31	454	259	666	1e-19	101
rs:XP_004012784	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Ovis aries].	26.35	425	242	14	60	455	310	692	2e-19	102
rs:WP_041741519	DNA topoisomerase I [Caldicellulosiruptor kronotskyensis].	25.24	420	255	13	54	454	231	610	2e-19	101
rs:WP_027192232	DNA topoisomerase I [Desulfovibrio putealis].	25.36	414	254	11	54	452	232	605	2e-19	101
rs:WP_018132573	hypothetical protein [Effusibacillus pohliae].	25.62	441	259	15	41	457	222	617	2e-19	101
rs:WP_019234829	DNA topoisomerase I [Legionella anisa].	26.64	443	260	16	28	452	226	621	2e-19	101
tr:W5NPJ3_SHEEP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.35	425	242	14	60	455	329	711	2e-19	102
rs:WP_021067110	MULTISPECIES: DNA topoisomerase I [Exiguobacterium].	26.39	432	265	15	41	454	218	614	2e-19	101
rs:WP_047336170	DNA topoisomerase I [Pseudomonas fluorescens].	27.55	392	231	15	68	446	276	627	2e-19	101
rs:WP_037007718	DNA topoisomerase I, partial [Pseudomonas fluorescens].	27.55	392	231	15	68	446	140	491	2e-19	101
rs:WP_034147900	DNA topoisomerase I [Pseudomonas fluorescens].	28.36	409	244	16	47	446	259	627	2e-19	101
tr:J9FZL6_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central domain protein {ECO:0000313|EMBL:EJX00432.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EJX00432.1}; Flags: Fragment;	33.98	206	115	5	205	401	5	198	2e-19	97.8
rs:WP_021789620	hypothetical protein [Thermoplasmatales archaeon Gpl].	25.31	399	252	13	18	408	224	584	2e-19	101
rs:WP_026680881	DNA topoisomerase I [Bacillus megaterium].	24.69	409	248	13	69	457	246	614	2e-19	101
rs:WP_004253452	DNA topoisomerase I [Streptococcus mitis].	25.24	412	241	13	60	452	248	611	2e-19	101
rs:WP_012285560	DNA topoisomerase I [Caulobacter sp. K31].	27.53	425	237	16	61	452	243	629	2e-19	101
rs:WP_043037304	DNA topoisomerase [Streptococcus equi].	26.11	337	212	8	67	398	270	574	2e-19	101
rs:WP_020189432	DNA topoisomerase I [Kurthia sp. Dielmo].	23.35	484	297	17	1	452	170	611	2e-19	101
rs:WP_046786461	DNA topoisomerase I [Pseudomonas putida].	27.32	410	247	13	47	446	258	626	2e-19	101
rs:WP_036087905	DNA topoisomerase I [Leptotrichia hofstadii].	27.09	358	204	11	40	379	214	532	2e-19	101
rs:WP_000179669	DNA topoisomerase I [Streptococcus sp. oral taxon 071].	24.82	415	239	14	60	452	248	611	2e-19	101
rs:WP_040564319	DNA topoisomerase I [Kingella denitrificans].	26.62	432	257	13	41	452	227	618	2e-19	101
rs:WP_011060262	MULTISPECIES: topoisomerase I [Pseudomonas fluorescens group].	27.55	392	231	15	68	446	276	627	2e-19	101
rs:WP_024409560	DNA topoisomerase [Streptococcus suis].	28.99	345	198	12	60	396	266	571	2e-19	101
rs:WP_008009864	DNA topoisomerase I [Haloterrigena limicola].	23.94	426	274	13	40	454	246	632	2e-19	101
tr:W5NPJ8_SHEEP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.35	425	242	14	60	455	312	694	2e-19	101
rs:WP_045591152	DNA topoisomerase I [Streptococcus mitis].	24.33	411	246	12	60	452	248	611	2e-19	101
rs:WP_010269604	DNA topoisomerase I [Paenibacillus senegalensis].	25.48	416	243	15	66	457	242	614	2e-19	101
rs:WP_027906767	DNA topoisomerase I [Pseudomonas taiwanensis].	27.74	411	244	14	47	446	258	626	2e-19	101
rs:WP_022091340	DNA topoisomerase [Lachnospiraceae bacterium CAG:25].	25.59	426	258	13	50	457	229	613	2e-19	101
rs:WP_013037640	DNA topoisomerase I [Methanohalophilus mahii].	22.98	409	274	10	51	454	251	623	2e-19	101
tr:F0IMD6_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.85	436	257	13	40	452	230	613	2e-19	101
rs:WP_000876323	DNA topoisomerase [Streptococcus agalactiae].	26.11	337	212	8	67	398	270	574	2e-19	101
rs:WP_042609034	DNA topoisomerase I [Pseudomonas fluorescens].	27.87	409	246	16	47	446	259	627	2e-19	101
rs:WP_003248770	DNA topoisomerase I [Pseudomonas putida].	27.49	411	245	14	47	446	258	626	2e-19	101
rs:WP_045493307	DNA topoisomerase I [Pseudomonas sp. StFLB209].	27.59	395	227	15	68	446	276	627	2e-19	101
rs:WP_000179672	DNA topoisomerase I [Streptococcus mitis].	24.82	415	239	14	60	452	248	611	2e-19	101
rs:WP_042527530	DNA topoisomerase I [Coxiella burnetii].	26.29	426	254	13	48	452	236	622	2e-19	101
tr:E4SE67_CALK2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.24	420	255	13	54	454	230	609	2e-19	101
rs:WP_015095955	DNA topoisomerase I [Pseudomonas sp. UW4].	28.36	409	244	16	47	446	259	627	2e-19	101
rs:WP_035458482	DNA topoisomerase I [Alcanivorax sp. 97CO-5].	24.81	399	250	12	60	446	279	639	2e-19	101
rs:WP_040204980	MULTISPECIES: DNA topoisomerase I [Bacillus].	26.01	419	246	16	60	457	239	614	2e-19	101
rs:WP_020029559	hypothetical protein [gamma proteobacterium SCGC AAA076-P13].	25.70	393	242	11	77	458	286	639	2e-19	101
tr:A0A075MM36_9ARCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.59	455	235	17	40	454	254	649	2e-19	101
rs:WP_040146339	DNA topoisomerase I [Legionella pneumophila].	27.06	436	241	18	46	452	234	621	2e-19	101
rs:WP_044946190	DNA topoisomerase I [Clostridium sp. L2-50].	26.07	422	259	11	48	454	227	610	2e-19	101
rs:WP_023379575	DNA topoisomerase I subunit omega [Pseudomonas sp. VLB120].	27.74	411	244	14	47	446	258	626	2e-19	101
rs:WP_032806483	topoisomerase I, partial [Oenococcus oeni].	34.12	211	112	9	101	302	2	194	2e-19	96.7
rs:WP_036996267	DNA topoisomerase I, partial [Pseudomonas fluorescens].	27.55	392	231	15	68	446	132	483	2e-19	101
rs:WP_019470223	MULTISPECIES: topoisomerase I [Pseudomonas].	27.32	410	247	13	47	446	258	626	2e-19	101
rs:WP_037468625	DNA topoisomerase I [Sphingobium herbicidovorans].	28.15	437	252	17	40	452	219	617	2e-19	101
rs:WP_016914091	topoisomerase I [Halomonas stevensii].	27.83	406	228	17	65	452	283	641	2e-19	101
rs:WP_023023206	DNA topoisomerase I [Streptococcus sp. I-P16].	24.35	423	253	13	49	452	237	611	2e-19	101
rs:WP_011912884	topoisomerase I [Pseudomonas stutzeri].	25.36	422	265	12	42	452	253	635	2e-19	101
rs:WP_046328999	DNA topoisomerase I [Sneathia sp. Sn35].	27.63	333	189	10	61	377	236	532	2e-19	101
rs:WP_039179783	DNA topoisomerase I [Halomonas hydrothermalis].	27.83	406	228	17	65	452	283	641	2e-19	101
rs:WP_036610755	DNA topoisomerase I [Oribacterium sp. P6A1].	24.88	434	272	14	34	454	213	605	2e-19	101
rs:WP_037555750	DNA topoisomerase I [Sphingopyxis sp. LC363].	28.64	440	247	16	40	452	219	618	2e-19	101
rs:WP_021944413	DNA topoisomerase [Clostridium sp. CAG:264].	26.07	422	259	11	48	454	266	649	2e-19	101
rs:WP_046819513	DNA topoisomerase I [Pseudomonas putida].	28.12	409	245	16	47	446	259	627	2e-19	101
rs:WP_040286872	DNA topoisomerase I [Sporosarcina koreensis].	24.89	438	259	15	40	452	217	609	2e-19	101
rs:WP_006442126	DNA topoisomerase I [[Clostridium] hylemonae].	25.35	426	264	12	48	457	227	614	2e-19	101
rs:WP_013971714	MULTISPECIES: topoisomerase I [Pseudomonas].	27.49	411	245	14	47	446	258	626	2e-19	101
rs:WP_019096205	topoisomerase I [Pseudomonas putida].	27.32	410	247	13	47	446	258	626	2e-19	101
rs:WP_014591780	topoisomerase I [Pseudomonas putida].	27.49	411	245	14	47	446	258	626	2e-19	101
rs:WP_014844720	DNA topoisomerase I [Legionella pneumophila].	27.06	436	241	18	46	452	234	621	2e-19	101
rs:WP_015827822	DNA topoisomerase I [Hirschia baltica].	25.17	433	269	12	47	454	231	633	2e-19	101
rs:WP_031496005	DNA topoisomerase I [Bryobacter aggregatus].	28.01	357	214	9	41	384	253	579	2e-19	101
rs:WP_042735212	DNA topoisomerase I [Lachnospiraceae bacterium TWA4].	26.17	428	249	15	48	454	221	602	2e-19	101
rs:WP_045284154	DNA topoisomerase I [Enterobacter sp. 35032].	26.50	434	256	18	38	459	215	597	2e-19	101
rs:WP_012271345	topoisomerase I [Pseudomonas putida].	27.49	411	245	14	47	446	258	626	2e-19	101
rs:WP_041122387	DNA topoisomerase I [Jeotgalibacillus alimentarius].	25.17	433	254	18	50	457	227	614	2e-19	101
rs:WP_007974049	topoisomerase I [Pseudomonas sp. GM33].	28.36	409	244	16	47	446	259	627	2e-19	101
rs:WP_026756381	DNA topoisomerase I [Sediminimonas qiaohouensis].	27.29	447	262	16	31	454	221	627	2e-19	101
rs:WP_045475869	DNA topoisomerase I [Thioploca ingrica].	26.68	431	253	15	44	452	232	621	2e-19	101
rs:WP_016714898	topoisomerase I [Pseudomonas monteilii].	27.49	411	245	14	47	446	258	626	2e-19	101
rs:WP_025754460	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	27.49	411	245	14	47	446	258	626	2e-19	101
tr:D4JW68_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.66	365	244	10	69	417	277	626	2e-19	101
tr:F0EZX1_9NEIS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.62	432	257	13	41	452	242	633	2e-19	101
rs:WP_000179626	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.88	414	240	14	60	452	248	611	2e-19	101
rs:WP_000179665	DNA topoisomerase I [Streptococcus oralis].	24.69	405	240	12	66	452	254	611	2e-19	101
rs:WP_011947523	DNA topoisomerase I [Legionella pneumophila].	27.06	436	241	18	46	452	234	621	2e-19	101
rs:WP_012220043	DNA topoisomerase I [Coxiella burnetii].	26.29	426	254	13	48	452	236	622	2e-19	101
rs:WP_028239585	DNA topoisomerase I [Pseudomonas azotifigens].	26.46	393	238	12	66	446	272	625	2e-19	101
rs:WP_047600133	DNA topoisomerase I [Pseudomonas sp. RIT288].	27.62	391	230	15	69	446	277	627	2e-19	101
rs:WP_010559875	topoisomerase I [Pseudoalteromonas spongiae].	27.71	350	206	10	47	384	260	574	2e-19	101
rs:WP_026585548	DNA topoisomerase I [Bacillus sp. J33].	25.68	444	270	17	34	457	210	613	2e-19	101
rs:WP_036557354	DNA topoisomerase I [Oceanicola sp. MCTG156(1a)].	27.31	432	255	15	47	454	231	627	2e-19	101
rs:XP_010120298	PREDICTED: DNA topoisomerase 3-alpha [Chlamydotis macqueenii].	26.07	445	264	16	39	456	290	696	2e-19	101
tr:C2ZBM2_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.06	443	274	16	34	457	203	606	2e-19	101
rs:WP_039792923	DNA topoisomerase I, partial [Pseudomonas agarici].	27.55	392	231	15	68	446	142	493	2e-19	101
tr:A0A091KTW7_9GRUI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.07	445	264	16	39	456	270	676	2e-19	101
tr:F0I228_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.67	431	264	12	40	452	230	613	2e-19	101
rs:XP_002189800	PREDICTED: DNA topoisomerase 3-alpha [Taeniopygia guttata].	25.62	445	266	15	39	456	288	694	2e-19	101
rs:WP_008430847	DNA topoisomerase I [Planococcus donghaensis].	24.30	465	278	18	18	452	187	607	2e-19	101
rs:WP_001286970	DNA topoisomerase I [Bacillus cereus].	25.06	443	274	16	34	457	210	613	2e-19	101
rs:WP_039760792	DNA topoisomerase I [Pseudomonas fluorescens].	27.87	409	246	16	47	446	259	627	2e-19	101
tr:K1TSU6_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC76072.1}; Flags: Fragment;	27.71	249	173	4	37	282	136	380	2e-19	100
rs:WP_024858121	DNA topoisomerase III [Ruminococcus albus].	25.61	371	242	11	74	428	275	627	2e-19	101
rs:WP_047531368	DNA topoisomerase I [Pseudomonas sp. 11/12A].	28.36	409	244	16	47	446	259	627	2e-19	101
rs:WP_025052246	DNA topoisomerase I [Sulfitobacter noctilucae].	27.65	434	262	15	41	454	225	626	2e-19	101
rs:WP_011588296	MULTISPECIES: topoisomerase I [Alcanivorax].	24.81	399	250	12	60	446	279	639	2e-19	101
rs:WP_025260740	DNA topoisomerase I [Pseudomonas cichorii].	27.45	408	249	14	47	446	259	627	2e-19	101
rs:WP_031561748	DNA topoisomerase I [Ruminococcus flavefaciens].	26.54	437	251	17	41	452	219	610	2e-19	101
rs:WP_043580749	DNA topoisomerase I [Gemmatimonas phototrophica].	25.65	499	287	18	1	458	169	624	2e-19	101
rs:WP_016646110	DNA topoisomerase I [Campylobacter ureolyticus].	27.08	421	243	16	47	450	224	597	2e-19	101
rs:WP_026475992	DNA topoisomerase I [Alkaliphilus transvaalensis].	24.26	470	264	13	36	450	212	644	2e-19	101
tr:U7S059_ENTFL	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ERT25498.1}; Flags: Fragment;	34.78	184	104	4	281	455	1	177	2e-19	96.7
gp:CP003885_439	DNA topoisomerase I [Legionella pneumophila subsp. pneumophila LPE509]	27.06	436	241	18	46	452	208	595	2e-19	101
rs:WP_044740086	DNA topoisomerase I [Bacillus mycoides].	27.27	429	251	19	40	452	269	652	2e-19	101
rs:WP_025111056	DNA topoisomerase I [Pseudomonas sp. H1h].	27.87	409	246	16	47	446	259	627	2e-19	101
rs:WP_012276709	topoisomerase I [Shewanella halifaxensis].	29.39	347	196	12	57	388	271	583	2e-19	101
rs:WP_014407586	DNA topoisomerase I [Streptococcus pyogenes].	23.79	454	279	14	19	452	218	624	2e-19	100
rs:WP_045428428	DNA topoisomerase I [Pseudomonas sp. MT-1].	26.12	402	241	13	68	452	273	635	2e-19	101
rs:WP_032840878	DNA topoisomerase I [Fusobacterium sp. CM21].	27.68	354	204	11	40	377	220	537	2e-19	101
rs:WP_012467319	DNA topoisomerase I [Chlorobium limicola].	25.85	441	251	15	47	454	235	632	2e-19	101
rs:WP_032863314	DNA topoisomerase I [Pseudomonas sp. FH4].	28.12	409	245	16	47	446	259	627	2e-19	101
rs:WP_042902188	DNA topoisomerase I [Streptococcus oralis].	24.82	415	239	14	60	452	248	611	2e-19	100
rs:WP_002719330	DNA topoisomerase I [Rhodobacter sphaeroides].	27.33	439	261	14	41	454	223	628	2e-19	101
rs:WP_008493015	DNA topoisomerase I [Acidocella sp. MX-AZ02].	27.79	421	247	15	60	452	244	635	2e-19	101
rs:WP_038442188	DNA topoisomerase I [Pseudomonas fluorescens].	28.26	407	243	16	49	446	261	627	2e-19	101
rs:WP_009826132	DNA topoisomerase I [Sulfitobacter sp. NAS-14.1].	27.31	432	255	15	47	454	231	627	2e-19	101
rs:WP_000179667	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.82	415	239	14	60	452	248	611	2e-19	100
rs:WP_020192583	topoisomerase I, partial [Pseudomonas putida].	27.49	411	245	14	47	446	258	626	2e-19	101
rs:WP_005945902	hypothetical protein, partial [Blautia hydrogenotrophica].	28.75	240	152	6	72	295	300	536	2e-19	100
rs:WP_035903139	DNA topoisomerase I [Fusobacterium necrophorum].	27.47	375	209	12	22	378	204	533	2e-19	100
rs:WP_002382349	DNA topoisomerase I, partial [Enterococcus faecalis].	24.37	439	272	17	34	452	211	609	2e-19	100
rs:WP_032913578	DNA topoisomerase I [Streptococcus sanguinis].	23.67	431	264	12	40	452	227	610	2e-19	100
rs:WP_032911148	DNA topoisomerase I [Streptococcus sanguinis].	24.03	466	271	15	18	452	197	610	2e-19	100
rs:WP_028381135	DNA topoisomerase I [Legionella cherrii].	28.50	407	233	16	65	452	254	621	2e-19	100
rs:WP_041477349	DNA topoisomerase I [Pseudomonas sp. PTA1].	27.87	409	246	16	47	446	259	627	2e-19	101
rs:WP_018704610	hypothetical protein [Anaeromusa acidaminophila].	25.75	431	262	13	45	455	219	611	2e-19	100
tr:A0A091S7V4_NESNO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.25	461	273	18	24	456	257	678	2e-19	101
tr:C8PI89_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.23	432	245	17	43	450	220	597	2e-19	100
rs:WP_043633714	DNA topoisomerase I [Desulfovibrio sp. TomC].	27.10	417	238	15	56	452	234	604	2e-19	100
rs:WP_023839464	DNA topoisomerase I [Blastomonas sp. CACIA14H2].	28.26	414	239	15	60	452	241	617	2e-19	101
rs:WP_022685102	DNA topoisomerase I [Sphingomonas phyllosphaerae].	28.84	430	242	16	48	452	227	617	2e-19	101
rs:WP_007149281	topoisomerase I [Alcanivorax sp. DG881].	24.81	399	250	12	60	446	279	639	2e-19	101
rs:WP_007438736	DNA topoisomerase I [Acetobacteraceae bacterium AT-5844].	26.64	443	266	14	41	454	225	637	2e-19	101
rs:WP_018465097	hypothetical protein [Meiothermus timidus].	26.62	417	236	14	61	459	246	610	2e-19	101
tr:A0A091MVC1_CARIC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.29	445	263	16	39	456	270	676	2e-19	101
rs:WP_000179624	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.33	411	246	12	60	452	248	611	3e-19	100
rs:WP_016168270	DNA topoisomerase I [Acinetobacter tandoii].	27.27	429	251	19	40	452	269	652	3e-19	101
rs:WP_013437787	MULTISPECIES: DNA topoisomerase I [Lactobacillus].	24.66	442	273	13	34	457	223	622	3e-19	100
rs:WP_038839607	DNA topoisomerase I [Legionella pneumophila].	27.06	436	241	18	46	452	234	621	3e-19	100
rs:WP_043106819	DNA topoisomerase I [endosymbiont of unidentified scaly snail isolate Monju].	27.63	427	249	15	46	452	232	618	3e-19	100
rs:XP_010073739	PREDICTED: DNA topoisomerase 3-alpha [Pterocles gutturalis].	26.29	445	263	16	39	456	290	696	3e-19	101
rs:WP_037965068	DNA topoisomerase I [Sulfitobacter pontiacus].	27.78	432	253	17	47	454	231	627	3e-19	101
tr:D5T991_LEGP2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.06	436	241	18	46	452	208	595	3e-19	100
rs:WP_013129043	DNA topoisomerase I [Thermosphaera aggregans].	26.39	379	230	12	60	425	282	624	3e-19	100
rs:WP_022474281	DNA topoisomerase [Ruminococcus sp. CAG:353].	25.93	428	249	15	48	452	226	608	3e-19	100
rs:WP_038439819	DNA topoisomerase I [Fusobacterium nucleatum].	26.94	386	223	13	26	391	209	555	3e-19	100
rs:WP_000179628	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.58	415	240	14	60	452	248	611	3e-19	100
rs:WP_029896729	DNA topoisomerase I [Desulfovibrio sp. L21-Syr-AB].	25.88	425	251	13	47	452	235	614	3e-19	100
tr:D7WI61_BACCE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFI65101.1};	33.94	165	105	2	232	392	4	168	3e-19	95.9
tr:A0A091EPK2_CORBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.96	443	267	16	39	456	270	676	3e-19	101
tr:A7VIM6_9CLOT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.07	422	259	11	48	454	258	641	3e-19	100
rs:WP_039589079	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	28.12	409	245	16	47	446	259	627	3e-19	100
rs:WP_036885478	DNA topoisomerase I, partial [Prevotella disiens].	28.74	247	170	5	141	384	15	258	3e-19	99.0
rs:WP_034303372	DNA topoisomerase I [Alkalibacterium sp. AK22].	25.18	425	263	11	43	452	222	606	3e-19	100
rs:WP_028246918	DNA topoisomerase I [Pseudobutyrivibrio ruminis].	23.56	433	278	11	41	457	220	615	3e-19	100
rs:WP_019365904	topoisomerase I [Pseudomonas luteola].	26.52	411	257	11	42	446	255	626	3e-19	100
rs:WP_028287613	DNA topoisomerase I [Oceanicola nanhaiensis].	28.31	431	253	13	47	454	231	628	3e-19	100
rs:WP_031874330	DNA topoisomerase III, partial [Staphylococcus aureus].	27.80	241	152	4	35	269	227	451	3e-19	99.8
rs:XP_008631835	PREDICTED: DNA topoisomerase 3-alpha, partial [Corvus brachyrhynchos].	25.96	443	267	16	39	456	271	677	3e-19	101
tr:E9FHA4_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.69	405	240	12	66	452	260	617	3e-19	100
rs:WP_008368407	topoisomerase I [Pseudomonas sp. M47T1].	27.59	406	247	14	49	446	260	626	3e-19	100
tr:A0A0B1U4C5_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.10	417	238	15	56	452	245	615	3e-19	100
rs:WP_012562937	DNA topoisomerase I [Oligotropha carboxidovorans].	26.61	436	238	15	60	454	243	637	3e-19	100
rs:WP_007949671	topoisomerase I [Pseudomonas sp. GM24].	27.87	409	246	16	47	446	259	627	3e-19	100
rs:WP_048111619	topoisomerase I [Candidatus Methanoplasma termitum].	25.53	423	263	15	47	458	246	627	3e-19	100
rs:WP_016775493	MULTISPECIES: topoisomerase I [Pseudomonas].	27.87	409	246	16	47	446	259	627	3e-19	100
rs:WP_040346999	DNA topoisomerase I [Anaeroglobus geminatus].	27.36	435	241	20	45	452	279	665	3e-19	100
tr:A0A093C8L8_9AVES	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.29	445	263	16	39	456	270	676	3e-19	101
rs:WP_018378171	DNA topoisomerase I [Streptococcus ovis].	24.38	447	265	14	29	452	217	613	3e-19	100
rs:WP_027596626	DNA topoisomerase I [Pseudomonas sp. LAIL14HWK12:I7].	26.72	408	252	13	47	446	258	626	3e-19	100
rs:WP_006341833	DNA topoisomerase I [Parachlamydia acanthamoebae].	25.29	431	253	16	47	454	240	624	3e-19	100
rs:WP_025338324	DNA topoisomerase I [Pseudomonas sp. FGI182].	27.25	411	246	14	47	446	258	626	3e-19	100
rs:WP_010948299	DNA topoisomerase I [Legionella pneumophila].	27.06	436	241	18	46	452	234	621	3e-19	100
rs:WP_014262163	DNA topoisomerase I [Filifactor alocis].	26.10	433	231	13	69	449	248	643	3e-19	100
rs:WP_027266315	DNA topoisomerase I [Legionella pneumophila].	27.06	436	241	18	46	452	234	621	3e-19	100
rs:WP_028399000	DNA topoisomerase I [Bacillus panaciterrae].	25.42	417	251	15	60	457	237	612	3e-19	100
rs:WP_035960666	hypothetical protein, partial [Fusobacterium ulcerans].	27.15	383	232	15	77	449	166	511	3e-19	100
rs:WP_045224643	DNA topoisomerase I [Methylococcaceae bacterium 73a].	28.21	429	247	16	45	452	233	621	3e-19	100
rs:WP_014842657	DNA topoisomerase I [Legionella pneumophila].	27.06	436	241	18	46	452	234	621	3e-19	100
rs:WP_002715487	DNA topoisomerase I [Afipia felis].	27.46	426	247	15	60	454	243	637	3e-19	100
tr:H1PYH8_9FUSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.15	383	232	15	77	449	160	505	3e-19	100
rs:WP_000179625	DNA topoisomerase I [Streptococcus oralis].	24.33	411	246	12	60	452	248	611	3e-19	100
rs:WP_000179623	DNA topoisomerase I [Streptococcus sp. C300].	24.69	405	240	12	66	452	254	611	3e-19	100
rs:WP_037943341	DNA topoisomerase I [Sulfitobacter sp. CB2047].	27.78	432	253	17	47	454	231	627	3e-19	100
rs:WP_036642054	DNA topoisomerase I [Paenibacillus sp. FSL R5-808].	24.03	437	272	13	41	457	218	614	3e-19	100
rs:WP_022784507	DNA topoisomerase I [Lachnospiraceae bacterium NK4A179].	26.23	427	265	12	45	454	224	617	3e-19	100
rs:WP_033700418	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	26.67	390	235	12	69	446	276	626	3e-19	100
rs:WP_010652788	DNA topoisomerase I [Fluoribacter dumoffii].	26.82	425	256	15	46	452	234	621	3e-19	100
tr:A0A0B3AMM6_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.00	423	222	17	67	454	257	623	3e-19	100
rs:WP_038369385	DNA topoisomerase I [Pseudomonas chlororaphis].	27.87	409	246	16	47	446	259	627	3e-19	100
tr:A0A094NN34_9AVES	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.29	445	263	16	39	456	270	676	3e-19	100
rs:WP_014770598	DNA topoisomerase I [Sulfurospirillum barnesii].	28.82	399	212	17	76	452	257	605	3e-19	100
rs:WP_010768602	DNA topoisomerase 1 [Enterococcus phoeniculicola].	25.50	447	267	18	34	457	211	614	3e-19	100
rs:WP_008491745	DNA topoisomerase I [SAR86 cluster bacterium SAR86E].	28.47	281	164	7	77	354	287	533	3e-19	100
tr:N0DX73_STRPY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.41	337	211	8	67	398	285	589	3e-19	100
rs:WP_018153854	DNA topoisomerase I [Methanothermococcus thermolithotrophicus].	23.91	460	279	16	18	454	218	629	3e-19	100
rs:WP_019349908	DNA topoisomerase I [Fluoribacter dumoffii].	26.82	425	256	15	46	452	234	621	3e-19	100
rs:WP_011526737	DNA topoisomerase I [Lawsonia intracellularis].	24.24	425	268	11	43	452	221	606	3e-19	100
rs:XP_009699312	PREDICTED: DNA topoisomerase 3-alpha [Cariama cristata].	26.29	445	263	16	39	456	290	696	3e-19	100
rs:WP_010483129	topoisomerase I [Pseudomonas sp. S9].	26.87	402	238	14	68	452	275	637	3e-19	100
rs:WP_009594778	DNA topoisomerase I [Paenibacillus sp. HGF5].	24.49	437	270	14	41	457	218	614	3e-19	100
rs:WP_010797697	DNA topoisomerase 1 [Pseudomonas sp. HPB0071].	26.52	411	257	11	42	446	255	626	3e-19	100
rs:WP_002554104	topoisomerase I [Pseudomonas savastanoi].	28.01	407	244	16	49	446	261	627	3e-19	100
rs:WP_011216475	DNA topoisomerase I [Legionella pneumophila].	27.06	436	241	18	46	452	234	621	3e-19	100
rs:WP_033606327	DNA topoisomerase I [Streptococcus sp. CM6].	24.33	411	246	12	60	452	248	611	3e-19	100
rs:WP_000179668	DNA topoisomerase I [Streptococcus sp. oral taxon 058].	24.33	411	246	12	60	452	248	611	3e-19	100
rs:WP_039232154	DNA topoisomerase I [Bacillus thermotolerans].	26.84	421	256	15	50	452	227	613	3e-19	100
rs:WP_027267691	DNA topoisomerase I [Legionella pneumophila].	27.06	436	241	18	46	452	234	621	3e-19	100
rs:XP_010017397	PREDICTED: DNA topoisomerase 3-alpha [Nestor notabilis].	26.25	461	273	18	24	456	262	683	3e-19	100
rs:WP_028321406	DNA topoisomerase I [Desulfatiglans anilini].	27.44	441	253	16	38	452	213	612	3e-19	100
tr:D4K311_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.39	432	252	16	45	452	222	611	3e-19	100
rs:WP_010301563	DNA topoisomerase I [Kurthia sp. JC8E].	24.94	437	262	17	40	452	217	611	3e-19	100
rs:WP_046175067	DNA topoisomerase I [Domibacillus indicus].	23.95	430	273	12	40	452	217	609	3e-19	100
rs:WP_022318561	DNA topoisomerase [Dorea sp. CAG:317].	26.46	427	258	13	48	457	227	614	3e-19	100
rs:WP_033659604	DNA topoisomerase, partial [Enterococcus faecium].	36.48	159	92	3	207	365	1	150	3e-19	97.4
tr:G9YGB0_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.36	435	241	20	45	452	282	668	3e-19	100
rs:WP_015593131	DNA topoisomerase I [Bacillus sp. 1NLA3E].	24.94	429	265	16	47	457	224	613	3e-19	100
rs:WP_035428988	DNA topoisomerase I [Bacillus sp. UNC322MFChir4.1].	23.60	445	278	14	34	457	210	613	3e-19	100
rs:XP_007425114	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Python bivittatus].	26.30	422	247	15	60	455	215	598	3e-19	100
rs:WP_002352835	DNA topoisomerase, partial [Enterococcus faecium].	30.93	236	151	5	54	286	126	352	3e-19	98.2
rs:WP_041125153	DNA topoisomerase I, partial [Sulfurovum sp. FS06-10].	26.44	450	252	17	31	458	215	607	3e-19	100
rs:WP_007193248	DNA topoisomerase I [Thiocapsa marina].	27.32	410	237	14	65	452	250	620	3e-19	100
rs:WP_027919555	DNA topoisomerase I [Pseudomonas sp. URMO17WK12:I8].	27.74	411	244	14	47	446	259	627	3e-19	100
rs:WP_020564824	DNA topoisomerase I [Methylosarcina fibrata].	28.16	419	231	16	61	452	248	623	3e-19	100
rs:WP_037958625	DNA topoisomerase I [Sulfurospirillum sp. SCADC].	26.91	457	251	19	26	452	207	610	3e-19	100
rs:WP_009829664	DNA topoisomerase I [Rhodobacteraceae bacterium HTCC2083].	27.17	438	260	14	41	454	225	627	3e-19	100
rs:WP_034687887	DNA topoisomerase I [Enterococcus mundtii].	24.43	442	278	14	34	457	211	614	3e-19	100
rs:WP_005493764	DNA topoisomerase I [Pseudoalteromonas luteoviolacea].	26.71	423	258	14	35	446	250	631	3e-19	100
rs:XP_007425113	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Python bivittatus].	25.96	443	263	16	40	455	226	630	3e-19	100
rs:WP_016500743	DNA topoisomerase I [Pseudomonas putida].	27.07	410	248	13	47	446	258	626	3e-19	100
rs:WP_021002711	DNA topoisomerase I [Streptococcus intermedius].	24.34	419	256	12	50	452	237	610	3e-19	100
rs:XP_002923167	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha [Ailuropoda melanoleuca].	26.18	424	245	14	60	455	310	693	3e-19	100
rs:WP_009562909	DNA topoisomerase I [Rhodobacter sp. AKP1].	27.33	439	261	14	41	454	223	628	3e-19	100
tr:H0Z9W6_TAEGU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.62	445	266	15	39	456	272	678	3e-19	100
rs:WP_015010243	DNA topoisomerase I [Amphibacillus xylanus].	26.33	414	235	17	69	457	246	614	3e-19	100
rs:WP_003747402	DNA topoisomerase I [Listeria seeligeri].	25.17	429	248	17	50	452	227	608	3e-19	100
rs:WP_007426411	DNA topoisomerase I [Oceaniovalibus guishaninsula].	27.33	461	248	18	41	454	225	645	3e-19	100
rs:WP_016986750	topoisomerase I [Pseudomonas fluorescens].	27.87	409	246	16	47	446	259	627	3e-19	100
rs:WP_016391296	DNA topoisomerase I subunit omega [Pseudomonas plecoglossicida].	27.74	411	244	14	47	446	259	627	3e-19	100
rs:WP_009568636	DNA topoisomerase I [Streptococcus intermedius].	24.34	419	256	12	50	452	237	610	3e-19	100
rs:XP_004776594	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Mustela putorius furo].	26.42	424	244	14	60	455	310	693	3e-19	100
rs:WP_010139696	DNA topoisomerase I [Oceanicola sp. S124].	28.64	433	247	18	47	454	231	626	3e-19	100
rs:WP_046041393	DNA topoisomerase I [Pseudomonas fluorescens].	28.26	407	243	16	49	446	261	627	3e-19	100
rs:WP_042606499	DNA topoisomerase III, partial [Vibrio harveyi].	29.22	219	127	6	257	459	5	211	3e-19	97.1
rs:WP_002380330	DNA topoisomerase I [Enterococcus faecalis].	24.60	439	271	17	34	452	211	609	3e-19	100
tr:W4LII3_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.42	434	275	14	38	452	217	616	3e-19	100
rs:WP_011836973	DNA topoisomerase I [Streptococcus sanguinis].	23.85	436	257	13	40	452	230	613	3e-19	100
rs:WP_045098244	DNA topoisomerase I [Tatlockia micdadei].	26.36	478	272	19	3	452	195	620	3e-19	100
rs:WP_038560155	DNA topoisomerase I [Terribacillus aidingensis].	23.83	428	272	10	47	457	224	614	3e-19	100
rs:WP_047649347	DNA topoisomerase I [Enterococcus faecalis].	24.60	439	271	17	34	452	211	609	3e-19	100
rs:WP_023007343	topoisomerase I [Halomonas sp. PBN3].	28.57	406	225	19	70	458	291	648	3e-19	100
rs:WP_012083020	DNA topoisomerase I [Nitratiruptor sp. SB155-2].	27.12	424	245	15	47	452	225	602	3e-19	100
rs:XP_005494942	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Zonotrichia albicollis].	25.39	445	267	15	39	456	159	565	4e-19	100
rs:WP_046400357	DNA topoisomerase III, partial [Staphylococcus aureus].	28.85	208	137	2	35	236	227	429	4e-19	99.4
rs:WP_034844101	DNA topoisomerase I, partial [Inquilinus limosus].	28.08	406	239	11	77	454	263	643	4e-19	100
rs:WP_002357484	MULTISPECIES: DNA topoisomerase I [Enterococcus].	24.60	439	271	17	34	452	211	609	4e-19	100
rs:WP_011890947	DNA topoisomerase I [Chlorobium phaeovibrioides].	26.71	423	243	15	61	454	249	633	4e-19	100
rs:WP_038434096	DNA topoisomerase I [Streptococcus pyogenes].	23.79	454	279	15	19	452	218	624	4e-19	100
rs:WP_038371482	DNA topoisomerase I [Fusobacterium nucleatum].	27.40	354	205	11	40	377	220	537	4e-19	100
tr:E3ZYQ7_LISSE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.17	429	248	17	50	452	227	608	4e-19	100
rs:WP_032843600	DNA topoisomerase I [Fusobacterium nucleatum].	27.40	354	205	11	40	377	220	537	4e-19	100
rs:WP_048155879	DNA topoisomerase [Methanosarcina barkeri].	25.71	455	260	17	31	454	263	670	4e-19	100
rs:WP_040855033	DNA topoisomerase I [Thiorhodovibrio sp. 970].	24.94	437	266	10	36	452	236	630	4e-19	100
rs:XP_010390949	PREDICTED: DNA topoisomerase 3-alpha, partial [Corvus cornix cornix].	25.96	443	267	16	39	456	273	679	4e-19	100
rs:WP_033829233	DNA topoisomerase I [Bacillus sp. KW-12].	24.88	426	259	14	47	452	224	608	4e-19	100
rs:WP_037584519	DNA topoisomerase I [Streptococcus intermedius].	24.34	419	256	12	50	452	238	611	4e-19	100
rs:WP_046447381	DNA topoisomerase I, partial [Carnobacterium sp. N15.MGS-251].	25.53	427	257	14	47	454	226	610	4e-19	100
rs:WP_031514382	DNA topoisomerase I, partial [Desulfotomaculum alkaliphilum].	23.30	455	267	14	48	449	227	652	4e-19	100
rs:WP_010735743	DNA topoisomerase 1 [Enterococcus mundtii].	24.43	442	278	14	34	457	211	614	4e-19	100
rs:WP_046809665	DNA topoisomerase I [Pseudomonas psychrophila].	28.12	409	245	16	47	446	259	627	4e-19	100
rs:WP_016745005	DNA topoisomerase I, partial [Sphingomonas wittichii].	27.04	477	262	18	22	452	192	628	4e-19	100
tr:H8YX88_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.94	437	266	10	36	452	246	640	4e-19	100
rs:WP_007674523	DNA topoisomerase I [Caulobacter sp. AP07].	27.29	436	242	15	52	452	234	629	4e-19	100
rs:WP_040047345	DNA topoisomerase I [Bacillaceae bacterium MTCC 8252].	26.84	421	256	15	50	452	227	613	4e-19	100
rs:WP_014852237	topoisomerase I [Pseudomonas stutzeri].	26.12	402	241	13	68	452	273	635	4e-19	100
rs:WP_013120419	DNA topoisomerase I [Thermincola potens].	25.12	430	268	13	45	457	224	616	4e-19	100
rs:WP_012475813	DNA topoisomerase I [Chlorobium phaeobacteroides].	25.48	420	251	14	61	454	249	632	4e-19	100
rs:XP_007425112	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Python bivittatus].	26.30	422	247	15	60	455	283	666	4e-19	100
rs:WP_003547140	DNA topoisomerase I [Lactobacillus acidophilus].	26.11	406	241	13	69	457	259	622	4e-19	100
rs:XP_004776596	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Mustela putorius furo].	26.42	424	244	14	60	455	310	693	4e-19	100
rs:WP_002381874	DNA topoisomerase I [Enterococcus faecalis].	24.60	439	271	17	34	452	211	609	4e-19	100
tr:Q7P6B1_FUSNV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.40	354	205	11	40	377	223	540	4e-19	100
rs:WP_015254980	DNA topoisomerase I [Thermobacillus composti].	25.37	473	275	18	18	457	187	614	4e-19	100
tr:A0A093R579_PHACA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.84	445	265	16	39	456	270	676	4e-19	100
rs:WP_032915919	DNA topoisomerase I [Streptococcus sanguinis].	24.08	436	256	13	40	452	227	610	4e-19	100
tr:D2EGP7_PARA4	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.25	443	290	12	18	449	238	641	4e-19	100
rs:XP_004776595	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Mustela putorius furo].	26.42	424	244	14	60	455	310	693	4e-19	100
rs:WP_035268307	DNA topoisomerase I [Desulfitibacter alkalitolerans].	25.40	437	268	13	39	454	215	614	4e-19	100
rs:WP_010764920	DNA topoisomerase 1 [Enterococcus moraviensis].	24.72	441	268	17	34	452	211	609	4e-19	100
rs:WP_021210139	topoisomerase I [Pseudomonas stutzeri].	26.12	402	241	13	68	452	273	635	4e-19	100
rs:WP_022023449	DNA topoisomerase [Acinetobacter sp. CAG:196].	25.44	401	244	13	65	450	260	620	4e-19	100
rs:WP_026624475	DNA topoisomerase I [Eggerthia catenaformis].	26.82	399	231	12	77	459	254	607	4e-19	100
rs:WP_004803752	DNA topoisomerase I [Eggerthia catenaformis].	26.82	399	231	12	77	459	254	607	4e-19	100
rs:WP_040243726	DNA topoisomerase I [Chromohalobacter japonicus].	29.57	399	217	20	70	452	293	643	4e-19	100
rs:WP_047939993	DNA topoisomerase I [Bacillus circulans].	25.29	427	250	19	50	452	227	608	4e-19	100
rs:WP_020879642	DNA topoisomerase I [Desulfovibrio sp. X2].	24.70	417	256	13	54	452	244	620	4e-19	100
rs:WP_019723732	DNA topoisomerase I [Enterococcus mundtii].	24.43	442	278	14	34	457	211	614	4e-19	100
rs:WP_035247162	DNA topoisomerase I [Alcanivorax jadensis].	24.75	396	254	10	60	446	279	639	4e-19	100
rs:XP_007196359	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Balaenoptera acutorostrata scammoni].	24.26	441	254	16	40	453	127	514	4e-19	100
rs:WP_024543326	DNA topoisomerase I [actinobacterium SCGC AAA044-D11].	28.05	328	193	9	41	354	248	546	4e-19	100
gp:CP007024_751	DNA topoisomerase I [Streptococcus pyogenes STAB901]	23.79	454	279	15	19	452	218	624	4e-19	100
rs:WP_000179676	DNA topoisomerase I [Streptococcus oralis].	24.33	411	246	12	60	452	248	611	4e-19	100
rs:WP_029880927	MULTISPECIES: DNA topoisomerase I [Paenibacillus].	24.71	433	266	14	45	457	222	614	4e-19	100
rs:WP_031633891	hypothetical protein [Pseudomonas aeruginosa].	35.85	159	93	3	300	458	1	150	4e-19	94.7
rs:WP_012942649	DNA topoisomerase I [Haloterrigena turkmenica].	24.00	425	276	14	40	454	246	633	4e-19	100
rs:WP_027284170	DNA topoisomerase I [Rubritepida flocculans].	26.50	434	256	14	52	454	236	637	4e-19	100
rs:WP_019627543	DNA topoisomerase I [Thioalkalivibrio sp. AKL10].	28.92	370	203	10	36	384	233	563	4e-19	100
rs:WP_019340657	topoisomerase I [Pseudomonas stutzeri].	25.87	402	242	13	68	452	273	635	4e-19	100
rs:WP_033106624	DNA topoisomerase I [Microbacterium profundi].	32.28	316	167	13	51	356	268	546	4e-19	100
rs:WP_012961408	DNA topoisomerase III [Streptococcus gallolyticus].	26.92	338	208	10	67	398	274	578	4e-19	100
rs:WP_033629621	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.82	415	239	14	60	452	248	611	4e-19	100
tr:C3WNT3_FUSNV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.40	354	205	11	40	377	223	540	4e-19	100
tr:F3R6F7_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	24.60	439	271	17	34	452	37	435	4e-19	99.8
rs:WP_047984892	DNA topoisomerase I [Ornithinibacillus californiensis].	25.23	436	263	16	43	457	221	614	4e-19	100
rs:WP_030092621	DNA topoisomerase I [Sphingomonas sp. DC-6].	28.02	439	245	16	47	452	228	628	4e-19	100
rs:WP_006091896	DNA topoisomerase I [Natronorubrum tibetense].	24.14	435	281	13	31	454	241	637	4e-19	100
rs:WP_011702101	DNA topoisomerase I [Listeria welshimeri].	24.77	440	263	17	38	452	212	608	4e-19	100
rs:WP_015736334	DNA topoisomerase I [Paenibacillus sp. Y412MC10].	24.26	437	271	14	41	457	218	614	4e-19	100
tr:A0A0E9ZLX5_9PSED	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KIY39878.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIY39878.1};	27.25	411	246	14	47	446	258	626	4e-19	100
rs:XP_008684206	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha [Ursus maritimus].	25.62	445	262	15	40	455	256	660	4e-19	100
rs:WP_016171692	DNA topoisomerase 1 [Enterococcus dispar].	24.69	478	282	20	11	457	184	614	4e-19	100
rs:WP_028383191	DNA topoisomerase I [Legionella moravica].	27.88	434	240	17	46	452	234	621	4e-19	100
rs:WP_033924726	DNA topoisomerase I [Sphingomonas sp. 35-24ZXX].	28.74	414	237	15	60	452	241	617	4e-19	100
rs:XP_009090020	PREDICTED: DNA topoisomerase 3-alpha [Serinus canaria].	25.39	445	267	15	39	456	288	694	4e-19	100
rs:WP_043198376	DNA topoisomerase I [Pseudomonas putida].	27.07	410	248	13	47	446	258	626	4e-19	100
tr:F0I7E3_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.08	436	256	13	40	452	230	613	4e-19	100
rs:WP_028767265	DNA topoisomerase I [Shewanella fidelis].	27.78	360	214	10	42	388	257	583	4e-19	100
rs:WP_008184655	DNA topoisomerase I [Rhodobacteraceae bacterium HTCC2150].	27.46	437	260	14	41	454	225	627	4e-19	100
rs:WP_008837879	DNA topoisomerase I [Mesorhizobium alhagi].	27.31	443	252	17	45	452	228	635	4e-19	100
rs:WP_010829429	DNA topoisomerase 1 [Enterococcus faecalis].	24.60	439	271	17	34	452	211	609	4e-19	100
rs:WP_046407983	DNA topoisomerase I [Sphingomonas sp. Ag1].	28.31	431	243	16	48	452	227	617	4e-19	100
rs:XP_005494941	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Zonotrichia albicollis].	25.39	445	267	15	39	456	288	694	5e-19	100
sp:TOP1_STAHJ	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.47	425	260	15	47	452	224	606	5e-19	100
rs:WP_015072720	DNA topoisomerase I [Gluconobacter oxydans].	26.29	426	247	17	60	452	244	635	5e-19	100
rs:WP_038074878	DNA topoisomerase I [Thioclava pacifica].	25.23	436	270	13	41	454	222	623	5e-19	100
rs:WP_015501246	DNA topoisomerase I [Octadecabacter antarcticus].	27.17	438	258	16	41	452	225	627	5e-19	100
rs:WP_045850104	DNA topoisomerase I [Domibacillus enclensis].	24.52	420	263	14	50	452	227	609	5e-19	100
rs:WP_006064421	DNA topoisomerase I [Natronorubrum bangense].	23.29	425	278	12	40	454	248	634	5e-19	100
rs:XP_005426049	PREDICTED: DNA topoisomerase 3-alpha [Geospiza fortis].	25.39	445	267	15	39	456	288	694	5e-19	100
rs:XP_009508111	PREDICTED: DNA topoisomerase 3-alpha [Phalacrocorax carbo].	25.84	445	265	16	39	456	290	696	5e-19	100
rs:WP_022984562	topoisomerase I [Alcanivorax sp. P2S70].	25.81	399	246	12	60	446	279	639	5e-19	100
rs:WP_008497955	DNA topoisomerase I [Planococcus halocryophilus].	23.86	482	293	18	1	452	170	607	5e-19	100
rs:WP_007283133	DNA topoisomerase I [Gluconobacter thailandicus].	26.29	426	247	17	60	452	244	635	5e-19	100
rs:WP_033599499	DNA topoisomerase I [Enterococcus faecalis].	24.60	439	271	17	34	452	211	609	5e-19	100
tr:E6Q4P1_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CBI02152.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI02152.1};	26.15	455	276	14	23	457	202	616	5e-19	100
rs:WP_023508917	DNA topoisomerase I [Sporolactobacillus laevolacticus].	27.45	408	229	18	75	457	252	617	5e-19	100
rs:WP_047250598	DNA topoisomerase I [Thioalkalivibrio versutus].	28.92	370	203	10	36	384	233	563	5e-19	100
rs:WP_028856605	DNA topoisomerase III [Psychrilyobacter atlanticus].	27.96	329	200	11	66	385	265	565	5e-19	100
rs:WP_040653704	DNA topoisomerase I, partial [Oribacterium sp. oral taxon 078].	24.42	430	265	13	47	457	226	614	5e-19	100
tr:D4CLC3_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.42	430	265	13	47	457	226	614	5e-19	100
rs:WP_013499826	DNA topoisomerase III [Ruminococcus albus].	25.61	371	242	11	74	428	275	627	5e-19	100
rs:WP_037537327	DNA topoisomerase I [Staphylococcus haemolyticus].	24.47	425	260	15	47	452	224	606	5e-19	100
rs:WP_047987866	DNA topoisomerase I [Bacillus pseudalcaliphilus].	25.86	406	236	16	69	452	246	608	5e-19	100
rs:WP_007202531	DNA topoisomerase I [Fictibacillus macauensis].	24.72	441	279	12	34	457	210	614	5e-19	100
rs:WP_022430440	DNA topoisomerase III [Prevotella stercorea CAG:629].	29.10	244	162	6	162	398	4	243	5e-19	97.8
rs:WP_011976610	DNA topoisomerase I [Methanococcus maripaludis].	24.83	431	267	14	40	454	238	627	5e-19	100
rs:WP_018377913	DNA topoisomerase III [Streptococcus ovis].	27.62	344	215	10	60	399	264	577	5e-19	99.8
tr:A0A0D6PQ44_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.29	426	247	17	60	452	244	635	5e-19	100
rs:WP_031396094	DNA topoisomerase I, partial [Sphingomonas sp. STIS6.2].	28.19	486	276	19	1	452	171	617	5e-19	100
tr:N6UAY1_DENPD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.55	467	250	14	40	456	256	665	5e-19	100
tr:E3YPQ4_9LIST	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.18	425	253	16	50	452	227	608	5e-19	100
rs:WP_007979591	DNA topoisomerase I [Haladaptatus paucihalophilus].	24.14	406	257	13	60	454	267	632	5e-19	100
rs:XP_010159682	PREDICTED: DNA topoisomerase 3-alpha, partial [Eurypyga helias].	26.00	423	249	14	60	456	312	696	5e-19	100
rs:WP_037599285	DNA topoisomerase [Streptococcus sp. ACS2].	23.96	384	250	11	22	398	228	576	5e-19	99.8
rs:XP_005229069	PREDICTED: DNA topoisomerase 3-alpha [Falco peregrinus].	26.64	443	264	16	39	456	290	696	5e-19	100
rs:WP_018650578	DNA topoisomerase I [Thioalkalivibrio sp. ALMg3].	28.92	370	203	10	36	384	233	563	5e-19	100
rs:WP_009557733	DNA topoisomerase I [Lactobacillus equicursoris].	26.62	432	247	17	43	452	253	636	5e-19	100
rs:WP_020789377	DNA topoisomerase I [Fusobacterium nucleatum].	27.40	354	205	11	40	377	220	537	5e-19	100
rs:WP_020998619	DNA topoisomerase I [Streptococcus intermedius].	24.23	421	254	12	50	452	237	610	5e-19	100
rs:WP_015902075	DNA topoisomerase I [Nautilia profundicola].	26.39	432	240	17	47	454	224	601	5e-19	100
rs:WP_028611049	DNA topoisomerase I [Paenibacillus harenae].	24.94	429	260	14	50	457	227	614	5e-19	100
rs:WP_007522106	DNA topoisomerase I [Streptococcus tigurinus].	24.82	415	239	14	60	452	248	611	5e-19	100
rs:WP_016616347	DNA topoisomerase I [Enterococcus faecalis].	24.60	439	271	17	34	452	211	609	5e-19	100
rs:WP_017322230	DNA topoisomerase I [cyanobacterium PCC 7702].	26.93	349	214	9	41	379	254	571	5e-19	100
rs:WP_035186290	DNA topoisomerase I [Acidiphilium sp. JA12-A1].	26.48	423	248	15	60	452	244	633	5e-19	100
tr:B7A9J7_THEAQ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.23	427	246	12	47	454	257	633	5e-19	100
rs:WP_008050053	topoisomerase I [Pseudomonas sp. GM74].	28.26	407	243	16	49	446	261	627	5e-19	100
rs:WP_022523166	DNA topoisomerase 1 [Halomonas sp. A3H3].	27.99	393	219	16	77	452	296	641	5e-19	100
rs:WP_037558001	DNA topoisomerase I [Staphylococcus haemolyticus].	24.47	425	260	15	47	452	224	606	5e-19	100
rs:WP_004285114	DNA topoisomerase I [Neisseria weaveri].	25.67	487	255	15	41	454	225	677	5e-19	100
rs:WP_040186246	DNA topoisomerase I [Halomonas salina].	27.80	410	223	17	70	458	297	654	5e-19	100
rs:WP_008459965	DNA topoisomerase I [Lactobacillus equicursoris].	26.62	432	247	17	43	452	253	636	5e-19	100
rs:WP_034852229	DNA topoisomerase I [Inquilinus limosus].	27.44	441	266	13	41	454	227	640	5e-19	100
rs:WP_011255493	DNA topoisomerase I [Ehrlichia ruminantium].	25.11	438	256	14	47	452	232	629	5e-19	100
rs:WP_018938918	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	28.92	370	203	10	36	384	233	563	5e-19	100
rs:WP_038407211	DNA topoisomerase I [Listeria ivanovii].	24.94	429	249	17	50	452	227	608	5e-19	99.8
tr:A0A0B7GQ73_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.67	431	264	12	40	452	227	610	5e-19	99.8
rs:WP_023916231	DNA topoisomerase 1 [Streptococcus sanguinis].	24.08	436	256	13	40	452	227	610	5e-19	99.8
rs:WP_042057047	DNA topoisomerase I, partial [Acidomonas methanolica].	26.10	433	253	16	53	452	237	635	5e-19	100
rs:WP_012290577	DNA topoisomerase I [Finegoldia magna].	24.17	484	286	15	1	452	171	605	5e-19	99.8
rs:WP_018168364	DNA topoisomerase I [Thioalkalivibrio sp. ALMg9].	28.92	370	203	10	36	384	233	563	5e-19	100
rs:WP_022054850	DNA topoisomerase [Coprobacillus sp. CAG:605].	24.32	477	283	15	1	450	178	603	5e-19	99.8
rs:WP_040684450	DNA topoisomerase I [Thermus aquaticus].	26.23	427	246	12	47	454	245	621	5e-19	100
tr:T1C8H5_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD61689.1}; Flags: Fragment;	39.46	147	87	1	218	364	7	151	5e-19	93.6
rs:WP_027962277	DNA topoisomerase I [Halomonas halodenitrificans].	26.89	424	249	15	51	458	270	648	5e-19	100
rs:WP_031440482	MULTISPECIES: DNA topoisomerase I [Sphingomonas].	27.57	486	279	18	1	452	171	617	6e-19	100
rs:WP_037209660	DNA topoisomerase I [Rhodovulum sp. NI22].	27.11	439	260	14	41	454	225	628	6e-19	100
rs:WP_008466614	topoisomerase I [Pseudoalteromonas sp. BSi20439].	26.07	422	260	14	36	446	251	631	6e-19	100
rs:WP_004622029	DNA topoisomerase I [[Clostridium] papyrosolvens].	25.64	468	274	18	22	454	191	619	6e-19	99.8
rs:WP_011155021	DNA topoisomerase I [Ehrlichia ruminantium].	25.11	438	256	14	47	452	232	629	6e-19	100
tr:F7JRL0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.26	276	181	6	31	296	218	486	6e-19	99.4
tr:A0A023D3N6_ACIMT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.10	433	253	16	53	452	237	635	6e-19	100
tr:J6XCP6_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJX43731.1}; Flags: Fragment;	36.48	159	92	3	207	365	2	151	6e-19	96.7
rs:WP_009686278	MULTISPECIES: topoisomerase I [Pseudomonas].	27.25	411	246	14	47	446	258	626	6e-19	100
rs:WP_027876542	DNA topoisomerase I [Meiothermus cerbereus].	27.89	398	217	17	72	452	257	601	6e-19	100
tr:A0A094RFZ6_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KGA03558.1};	27.74	328	194	9	41	354	248	546	6e-19	100
rs:WP_003766673	DNA topoisomerase I [Listeria innocua].	24.83	447	270	18	29	452	205	608	6e-19	99.8
rs:WP_019568140	DNA topoisomerase I [Thioalkalivibrio sp. ALMg13-2].	28.92	370	203	10	36	384	233	563	6e-19	100
gpu:LN713927_4	DNA topoisomerase I (EC 5.99.1.2) [Pseudomonas fluorescens SBW25]	25.06	435	269	16	41	457	233	628	6e-19	99.8
rs:WP_046900255	DNA topoisomerase I [Gluconobacter oxydans].	26.65	424	248	17	60	452	244	635	6e-19	100
rs:WP_012194426	DNA topoisomerase I [Methanococcus maripaludis].	24.13	460	278	14	18	454	216	627	6e-19	100
rs:WP_010547138	topoisomerase I [gamma proteobacterium HIMB30].	27.47	415	235	16	44	446	255	615	6e-19	100
rs:XP_007451079	PREDICTED: DNA topoisomerase 3-beta-1 [Lipotes vexillifer].	24.26	441	254	16	40	453	263	650	6e-19	100
rs:WP_039784659	hypothetical protein, partial [Ancylobacter sp. FA202].	35.98	214	117	8	38	234	231	441	6e-19	98.6
rs:WP_015199327	DNA topoisomerase I [Calothrix parietina].	25.66	378	233	11	41	401	249	595	6e-19	100
rs:WP_018176248	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	28.92	370	203	10	36	384	233	563	6e-19	100
rs:WP_018951810	DNA topoisomerase I [Thioalkalivibrio sp. AKL12].	28.92	370	203	10	36	384	233	563	6e-19	100
rs:WP_009730244	DNA topoisomerase 1 [Streptococcus sp. F0441].	24.58	415	240	14	60	452	248	611	6e-19	99.8
rs:WP_008094100	topoisomerase I [Pseudomonas sp. GM84].	27.49	411	245	14	47	446	259	627	6e-19	100
tr:F9E0C3_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.85	436	257	13	40	452	230	613	6e-19	99.8
rs:WP_009286991	MULTISPECIES: DNA topoisomerase I [Halomonas].	27.99	393	219	16	77	452	296	641	6e-19	100
rs:WP_010286439	DNA topoisomerase I [Kurthia massiliensis].	24.31	432	271	14	40	452	217	611	6e-19	99.8
rs:WP_022295803	DNA topoisomerase [Firmicutes bacterium CAG:272].	24.71	425	267	14	43	446	250	642	6e-19	99.8
tr:F8XZ68_STRAG	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EGS28193.1};	30.12	259	166	7	143	398	9	255	6e-19	95.9
rs:WP_022306116	DNA topoisomerase [Roseburia sp. CAG:380].	25.36	422	262	11	48	454	227	610	6e-19	99.8
rs:WP_013639815	DNA topoisomerase I [Acidiphilium multivorum].	26.48	423	248	15	60	452	244	633	6e-19	100
rs:WP_037490985	DNA topoisomerase I [Snodgrassella alvi].	25.17	429	249	13	50	452	234	616	6e-19	99.8
rs:WP_044320774	DNA topoisomerase I [Pseudomonas amygdali].	28.01	407	244	16	49	446	261	627	6e-19	100
rs:WP_021055826	Topoisomerase IA [Haloquadratum walsbyi].	23.90	410	244	14	65	454	287	648	6e-19	100
rs:WP_028792557	DNA topoisomerase I [Thalassobaculum salexigens].	25.76	427	252	15	60	452	244	639	6e-19	100
tr:A0A090QXC2_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	39.47	114	69	0	36	149	251	364	6e-19	97.4
rs:WP_022153888	DNA topoisomerase [Firmicutes bacterium CAG:65].	25.58	430	253	15	47	454	226	610	6e-19	99.8
tr:F7JS33_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.68	258	174	6	43	296	231	482	6e-19	99.0
rs:WP_045062417	DNA topoisomerase I [Pseudomonas sp. ES3-33].	27.98	411	239	18	49	446	261	627	6e-19	99.8
rs:WP_044955363	DNA topoisomerase III, partial [Lachnospiraceae bacterium 1_4_56FAA].	29.03	248	166	6	43	286	231	472	6e-19	99.0
rs:WP_004620068	DNA topoisomerase I [Caulobacter vibrioides].	26.82	425	240	16	61	452	243	629	6e-19	99.8
rs:WP_044317786	DNA topoisomerase I [Pseudomonas amygdali].	28.01	407	244	16	49	446	261	627	6e-19	99.8
rs:WP_038506612	DNA topoisomerase [Leptospirillum ferriphilum].	25.81	430	268	12	41	452	218	614	6e-19	99.8
rs:WP_032583635	DNA topoisomerase I, partial [Bacteroides fragilis].	35.68	185	112	5	60	243	76	254	6e-19	95.9
rs:WP_008471813	DNA topoisomerase I [Lactobacillus hominis].	25.29	435	258	17	43	457	226	613	6e-19	99.8
rs:WP_007403904	MULTISPECIES: DNA topoisomerase I [Sphingomonas].	26.58	489	280	18	1	452	171	617	6e-19	99.8
rs:WP_022056000	DNA topoisomerase [Clostridium sp. CAG:167].	24.59	423	264	12	48	454	226	609	6e-19	99.8
tr:E8KPH4_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.85	436	257	13	40	452	230	613	6e-19	99.8
rs:WP_028411437	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.39	488	294	21	1	457	170	613	6e-19	99.8
rs:WP_007424321	DNA topoisomerase I [Acidiphilium sp. PM].	26.48	423	248	15	60	452	244	633	6e-19	99.8
tr:K2CQ65_9BACT	RecName: Full=DNA topoisomerase I, plasmid {ECO:0000256|SAAS:SAAS00003555}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	26.83	410	233	17	66	454	254	617	6e-19	99.8
rs:WP_033964691	DNA topoisomerase I [Sphingomonas sp. Ant H11].	27.72	487	277	18	1	452	171	617	6e-19	99.8
rs:WP_035406961	DNA topoisomerase I [Exiguobacterium sp. RIT341].	25.89	421	241	16	60	454	236	611	6e-19	99.8
rs:WP_038634524	DNA topoisomerase I [Pseudomonas chlororaphis].	24.62	398	255	11	74	457	260	626	6e-19	99.8
rs:WP_025727922	DNA topoisomerase I [Bacillus ginsengihumi].	24.24	425	257	14	50	452	227	608	7e-19	99.8
rs:WP_018883417	MULTISPECIES: DNA topoisomerase I [Paenibacillus].	25.23	428	260	15	50	457	227	614	7e-19	99.8
rs:WP_011941732	DNA topoisomerase I [Acidiphilium cryptum].	26.48	423	248	15	60	452	244	633	7e-19	99.8
rs:XP_006973659	PREDICTED: DNA topoisomerase 3-alpha [Peromyscus maniculatus bairdii].	26.18	424	245	14	60	455	310	693	7e-19	100
tr:A0A098EWQ6_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.60	443	266	16	34	452	210	608	7e-19	99.8
rs:WP_034755646	DNA topoisomerase I [Bacillus vietnamensis].	23.78	429	271	13	46	457	224	613	7e-19	99.8
rs:WP_040873068	DNA topoisomerase I, partial [delta proteobacterium NaphS2].	24.94	425	258	13	49	452	229	613	7e-19	99.8
tr:U6DA30_NEOVI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.42	424	244	14	60	455	280	663	7e-19	99.8
rs:WP_022176407	DNA topoisomerase [Firmicutes bacterium CAG:552].	25.21	480	291	18	1	452	168	607	7e-19	99.8
rs:WP_015062158	DNA topoisomerase III [Salmonella sp. 14].	36.25	160	91	2	300	459	1	149	7e-19	93.6
rs:WP_025785060	MULTISPECIES: DNA topoisomerase I [Sporosarcina].	24.60	435	264	16	40	452	217	609	7e-19	99.8
tr:K1R4T8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC44072.1}; Flags: Fragment;	31.30	262	157	8	182	428	4	257	7e-19	97.1
rs:WP_024275546	DNA topoisomerase I [Hyphomicrobium sp. 802].	27.73	458	248	15	43	452	227	649	7e-19	99.8
rs:WP_032908166	DNA topoisomerase I [Streptococcus sanguinis].	23.85	436	257	13	40	452	227	610	7e-19	99.8
rs:WP_000179629	DNA topoisomerase I [Streptococcus mitis].	24.33	411	246	12	60	452	248	611	7e-19	99.8
tr:A0A0C9PQX4_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.71	494	289	17	1	458	173	624	7e-19	99.8
tr:A0A091G737_9AVES	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.77	423	250	14	60	456	292	676	7e-19	99.8
tr:J6QMH7_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJX69505.1}; Flags: Fragment;	36.48	159	92	3	207	365	2	151	7e-19	96.7
rs:WP_042560168	DNA topoisomerase I [Pseudomonas fluorescens].	27.87	409	246	16	47	446	259	627	7e-19	99.8
rs:WP_041099958	DNA topoisomerase I [Bacillus badius].	24.94	421	262	13	49	452	226	609	7e-19	99.8
rs:WP_005834274	MULTISPECIES: DNA topoisomerase I [Bacillales].	26.00	427	249	14	54	457	231	613	7e-19	99.8
rs:WP_007125556	DNA topoisomerase I [Lactobacillus ultunensis].	25.86	406	242	13	69	457	259	622	7e-19	99.8
rs:WP_019954750	DNA topoisomerase I [Loktanella vestfoldensis].	27.08	432	256	16	47	454	231	627	7e-19	99.8
rs:WP_043188271	DNA topoisomerase I [Pseudomonas rhizosphaerae].	26.47	408	253	14	47	446	259	627	7e-19	99.8
rs:WP_026472027	DNA topoisomerase I [Alkanindiges illinoisensis].	27.46	426	254	18	40	452	288	671	7e-19	99.8
rs:WP_039247669	DNA topoisomerase I [Brevundimonas nasdae].	26.82	425	250	14	60	454	242	635	7e-19	99.8
rs:WP_014052595	DNA topoisomerase I [halophilic archaeon DL31].	24.66	446	268	18	35	454	237	640	7e-19	99.8
tr:F0FDB0_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.85	436	257	13	40	452	230	613	7e-19	99.8
rs:XP_009560480	PREDICTED: DNA topoisomerase 3-alpha [Cuculus canorus].	25.77	423	250	14	60	456	312	696	7e-19	99.8
rs:XP_012872011	PREDICTED: DNA topoisomerase 3-alpha [Dipodomys ordii].	26.18	424	245	14	60	455	310	693	7e-19	99.8
rs:WP_019413034	DNA topoisomerase I [Paenisporosarcina sp. TG20].	23.55	484	293	17	1	452	170	608	7e-19	99.8
rs:WP_008956602	topoisomerase I [Halomonas sp. HAL1].	28.24	393	218	16	77	452	296	641	7e-19	99.8
rs:WP_042767797	DNA topoisomerase I [Streptococcus sp. DBCMS].	24.64	414	241	14	60	452	248	611	7e-19	99.8
rs:WP_016465755	DNA topoisomerase 1 [Streptococcus sp. HPH0090].	24.41	422	252	13	50	452	238	611	7e-19	99.8
tr:A0A0E9GA42_CHLTH	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CRH91278.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRH91278.1};	23.52	438	270	12	34	452	222	613	7e-19	99.8
tr:F3USB2_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.85	436	257	13	40	452	230	613	7e-19	99.8
rs:WP_046522153	DNA topoisomerase I [Bacillus sp. SA2-6].	24.59	423	258	15	50	452	227	608	7e-19	99.4
rs:WP_033102497	MULTISPECIES: DNA topoisomerase I [Alteromonadales].	26.07	422	260	14	36	446	251	631	7e-19	99.8
rs:WP_016899533	topoisomerase I [Pseudoalteromonas sp. PAMC 22718].	26.07	422	260	14	36	446	251	631	7e-19	99.8
rs:WP_016290460	DNA topoisomerase I [Lachnospiraceae bacterium 28-4].	25.00	444	270	14	28	454	213	610	7e-19	99.4
rs:WP_043713736	DNA topoisomerase I [Symbiobacterium thermophilum].	27.51	418	242	14	61	457	277	654	7e-19	99.8
rs:WP_013946764	DNA topoisomerase I [Hyphomicrobium sp. MC1].	27.73	458	248	15	43	452	227	649	7e-19	99.8
rs:WP_041738085	DNA topoisomerase I [Caldicellulosiruptor owensensis].	24.76	420	257	13	54	454	231	610	7e-19	99.4
rs:WP_006825523	DNA topoisomerase I [Natrialba taiwanensis].	24.20	405	258	13	60	454	267	632	7e-19	99.8
tr:E4Q5B6_CALOW	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.76	420	257	13	54	454	230	609	7e-19	99.4
rs:XP_012171191	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Bombus terrestris].	24.49	437	270	12	39	452	206	605	7e-19	99.8
rs:WP_042225319	DNA topoisomerase [Leptospirillum sp. Group II 'C75'].	25.12	430	271	12	41	452	206	602	7e-19	99.8
rs:WP_029330840	DNA topoisomerase I [Exiguobacterium oxidotolerans].	25.28	447	263	15	34	454	210	611	7e-19	99.4
rs:WP_014812474	DNA topoisomerase I [Desulfomonile tiedjei].	26.22	431	262	16	43	452	221	616	8e-19	99.8
tr:A0A0D6E964_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.23	393	222	15	77	452	296	641	8e-19	99.8
rs:WP_037029714	DNA topoisomerase I, partial [Psychrilyobacter atlanticus].	25.11	466	275	17	18	454	188	608	8e-19	99.4
rs:WP_026832621	DNA topoisomerase I [Exiguobacterium undae].	24.84	475	264	16	34	450	210	649	8e-19	99.4
rs:WP_006152356	DNA topoisomerase I [Streptococcus infantis].	25.00	412	242	13	60	452	230	593	8e-19	99.4
tr:Q67PC7_SYMTH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.51	418	242	14	61	457	269	646	8e-19	99.4
rs:WP_004855164	DNA topoisomerase I [Acinetobacter gerneri].	27.04	429	252	19	40	452	267	650	8e-19	99.8
rs:WP_023048968	topoisomerase I [Pseudomonas putida].	27.07	410	248	13	47	446	258	626	8e-19	99.8
tr:F0IUZ5_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.85	436	257	13	40	452	230	613	8e-19	99.4
tr:Q3TBE3_MOUSE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.29	445	259	16	40	455	264	668	8e-19	99.4
rs:WP_012063858	DNA topoisomerase I [Alkaliphilus metalliredigens].	23.98	442	248	13	61	450	240	645	8e-19	99.4
rs:WP_016485640	topoisomerase I [Pseudomonas putida].	27.07	410	248	13	47	446	258	626	8e-19	99.8
rs:WP_027726063	DNA topoisomerase I [Tuberibacillus calidus].	25.17	433	259	17	47	457	224	613	8e-19	99.4
rs:XP_007196358	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Balaenoptera acutorostrata scammoni].	24.26	441	254	16	40	453	263	650	8e-19	99.8
rs:WP_000179621	DNA topoisomerase I [Streptococcus sp. SK643].	24.82	415	239	14	60	452	248	611	8e-19	99.4
rs:WP_018939267	DNA topoisomerase I [Thioalkalivibrio sp. AKL11].	28.97	359	199	9	36	377	233	552	8e-19	99.8
rs:WP_043149963	DNA topoisomerase I [Sphingobium sp. Ant17].	25.62	484	291	17	1	452	171	617	8e-19	99.8
tr:A0A059XXD1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.81	430	268	12	41	452	272	668	8e-19	99.8
tr:F3SHN7_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.85	436	257	13	40	452	230	613	8e-19	99.4
rs:WP_006182012	DNA topoisomerase I [Natrinema pellirubrum].	24.15	410	258	12	57	454	281	649	8e-19	99.8
rs:WP_019821575	hypothetical protein, partial [Vibrio splendidus].	24.85	326	170	7	201	458	1	319	8e-19	96.7
rs:WP_010212659	DNA topoisomerase I, partial [Pseudomonas amygdali].	28.01	407	244	16	49	446	115	481	8e-19	99.4
rs:WP_036885247	hypothetical protein, partial [Prevotella disiens].	29.93	274	177	5	113	384	1	261	8e-19	97.4
rs:WP_045614986	DNA topoisomerase I [Streptococcus mitis].	25.00	412	242	13	60	452	248	611	8e-19	99.4
rs:WP_023534198	DNA topoisomerase I [Pseudomonas putida].	26.23	408	254	13	47	446	258	626	8e-19	99.8
rs:WP_008560543	DNA topoisomerase I [Ruegeria sp. R11].	26.41	462	253	17	41	454	225	647	8e-19	99.8
rs:WP_035579838	DNA topoisomerase I [Halomonas sp. TG39a].	27.23	393	222	15	77	452	296	641	8e-19	99.8
rs:WP_011568344	DNA topoisomerase I [Roseobacter denitrificans].	28.51	435	244	19	47	452	231	627	8e-19	99.8
rs:WP_032914166	DNA topoisomerase I [Streptococcus sanguinis].	23.85	436	257	13	40	452	227	610	8e-19	99.4
rs:WP_013464804	topoisomerase I [Pseudoalteromonas sp. SM9913].	26.07	422	260	14	36	446	251	631	8e-19	99.8
rs:WP_035808132	DNA topoisomerase I [Jeotgalicoccus sp. 13MG44_air].	25.23	432	260	17	40	452	218	605	8e-19	99.4
tr:A0A087NAY7_9SPHN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.62	484	291	16	1	452	171	617	8e-19	99.8
tr:U3KH13_FICAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.51	443	269	16	39	456	288	694	8e-19	99.8
rs:XP_004312664	PREDICTED: DNA topoisomerase 3-alpha [Tursiops truncatus].	25.89	421	250	14	60	455	310	693	8e-19	99.8
rs:WP_044157398	DNA topoisomerase I [Salinibacillus aidingensis].	23.35	484	304	16	1	457	170	613	8e-19	99.4
rs:WP_034769755	DNA topoisomerase I [Bacillus thermoamylovorans].	25.37	410	243	15	69	457	246	613	8e-19	99.4
rs:WP_032906559	DNA topoisomerase I [Streptococcus sanguinis].	23.85	436	257	13	40	452	227	610	8e-19	99.4
rs:WP_005720234	DNA topoisomerase I [Lactobacillus crispatus].	25.86	406	242	13	69	457	258	621	8e-19	99.4
rs:WP_037383189	DNA topoisomerase I [Smithella sp. SCADC].	25.00	424	264	12	47	452	225	612	8e-19	99.4
rs:WP_019722027	DNA topoisomerase I [Bacillus coagulans].	25.00	456	274	19	26	457	202	613	8e-19	99.4
rs:WP_026508777	DNA topoisomerase I [Butyrivibrio sp. MC2013].	24.88	426	259	13	48	454	231	614	9e-19	99.4
rs:WP_036688567	MULTISPECIES: DNA topoisomerase I [Paenibacillus].	25.52	431	255	15	50	457	227	614	9e-19	99.4
rs:WP_007474867	DNA topoisomerase I [Caminibacter mediatlanticus].	25.41	429	248	15	47	454	224	601	9e-19	99.4
rs:WP_016622928	hypothetical protein, partial [Enterococcus faecalis].	32.18	174	107	4	156	325	13	179	9e-19	94.0
rs:WP_045165305	DNA topoisomerase I [Thermoanaerobacter cellulolyticus].	26.00	427	258	13	47	454	223	610	9e-19	99.4
tr:S2YZQ0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.57	266	173	6	31	286	218	476	9e-19	98.6
rs:WP_016182471	DNA topoisomerase 1 [Enterococcus columbae].	25.00	440	265	18	40	457	218	614	9e-19	99.4
rs:WP_032844749	DNA topoisomerase I, partial [Fusobacterium nucleatum].	27.40	354	205	11	40	377	220	537	9e-19	99.4
rs:XP_005098681	PREDICTED: DNA topoisomerase 3-alpha-like [Aplysia californica].	25.87	460	277	15	18	450	252	674	9e-19	99.8
rs:WP_036659208	DNA topoisomerase I [Paenibacillus sp. FSL H8-457].	24.03	437	272	14	41	457	218	614	9e-19	99.4
rs:WP_025251782	DNA topoisomerase I [Corynebacterium vitaeruminis].	27.18	379	221	11	31	384	248	596	9e-19	99.8
rs:WP_031368295	hypothetical protein, partial [Clostridium botulinum].	27.14	269	154	8	186	450	3	233	9e-19	95.9
rs:WP_041848588	DNA topoisomerase I [Bacillus thermoamylovorans].	25.37	410	243	15	69	457	246	613	9e-19	99.4
tr:H1HVV1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.45	362	199	15	33	350	222	567	9e-19	99.0
rs:WP_005916915	DNA topoisomerase I [Fusobacterium hwasookii].	26.68	386	224	13	26	391	209	555	9e-19	99.4
rs:WP_032912913	DNA topoisomerase I [Streptococcus sanguinis].	23.85	436	257	13	40	452	227	610	9e-19	99.4
rs:WP_035102953	DNA topoisomerase III, partial [Coprococcus sp. HPP0074].	28.57	266	173	6	31	286	218	476	9e-19	98.6
tr:A0A0D6A3Q4_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.04	407	240	14	69	457	257	620	9e-19	99.4
rs:XP_004266833	PREDICTED: DNA topoisomerase 3-alpha [Orcinus orca].	25.89	421	250	14	60	455	310	693	9e-19	99.8
rs:WP_022272018	DNA topoisomerase [Eubacterium siraeum CAG:80].	25.42	480	263	19	4	452	195	610	9e-19	99.4
rs:WP_017927245	DNA topoisomerase I [Loktanella hongkongensis].	26.41	462	257	17	41	454	225	651	9e-19	99.4
rs:WP_032913392	DNA topoisomerase I [Streptococcus sanguinis].	23.85	436	257	13	40	452	227	610	9e-19	99.4
rs:WP_004207248	DNA topoisomerase I [Sphingobium yanoikuyae].	26.19	485	287	18	1	452	171	617	9e-19	99.4
rs:WP_011139337	DNA topoisomerase I [Wolinella succinogenes].	26.12	425	252	15	47	454	224	603	9e-19	99.4
rs:WP_011506859	topoisomerase I [Chromohalobacter salexigens].	29.01	393	227	17	70	452	293	643	9e-19	99.4
rs:XP_012171190	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Bombus terrestris].	24.49	437	270	12	39	452	256	655	9e-19	99.4
rs:WP_000179627	DNA topoisomerase I [Streptococcus mitis].	24.09	411	247	12	60	452	248	611	9e-19	99.4
rs:WP_028632472	DNA topoisomerase I [Pseudomonas parafulva].	27.07	410	248	13	47	446	259	627	9e-19	99.4
rs:WP_016271548	DNA topoisomerase III [Bacteroides vulgatus].	28.75	327	194	10	68	385	266	562	9e-19	99.0
rs:WP_042144852	DNA topoisomerase I [Paucisalibacillus sp. EB02].	23.45	469	289	17	18	457	187	614	9e-19	99.4
rs:WP_041069001	DNA topoisomerase I [Pseudomonas sp. W15Feb9B].	27.37	391	231	15	69	446	277	627	9e-19	99.4
rs:WP_047295278	DNA topoisomerase I [Pseudomonas fluorescens].	27.37	391	231	15	69	446	277	627	9e-19	99.4
rs:WP_024018204	DNA topoisomerase I [Sphingobium sp. C100].	27.05	488	279	18	1	452	171	617	9e-19	99.4
rs:XP_011577577	PREDICTED: DNA topoisomerase 3-alpha [Aquila chrysaetos canadensis].	26.07	445	264	16	39	456	284	690	9e-19	99.4
rs:WP_032910423	DNA topoisomerase I [Streptococcus sanguinis].	23.85	436	257	13	40	452	227	610	9e-19	99.4
tr:D8EYS4_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.94	425	258	13	49	452	229	613	9e-19	99.4
rs:WP_039808869	DNA topoisomerase I [Jeotgalibacillus sp. D5].	24.48	429	262	15	50	457	227	614	9e-19	99.4
rs:WP_043532255	DNA topoisomerase I [Halomonas xinjiangensis].	29.08	392	217	17	77	452	300	646	9e-19	99.4
rs:WP_036757601	DNA topoisomerase I [Peptoniphilus lacrimalis].	25.00	412	242	13	60	452	248	611	9e-19	99.4
rs:WP_015468187	DNA topoisomerase I [Micavibrio aeruginosavorus].	26.29	445	256	18	45	454	231	638	9e-19	99.4
tr:F3UXP6_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.85	436	257	13	40	452	230	613	9e-19	99.4
tr:U4QTL0_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.58	430	269	13	41	452	269	665	9e-19	99.4
rs:XP_003996416	PREDICTED: DNA topoisomerase 3-alpha [Felis catus].	26.18	424	245	14	60	455	310	693	1e-18	99.4
rs:WP_016837424	DNA topoisomerase I [Ureibacillus thermosphaericus].	24.65	434	265	16	40	452	217	609	1e-18	99.0
rs:WP_032914840	DNA topoisomerase I [Streptococcus sanguinis].	23.85	436	257	13	40	452	227	610	1e-18	99.0
rs:WP_023488722	DNA topoisomerase [Lactobacillus crispatus].	25.86	406	242	13	69	457	258	621	1e-18	99.4
rs:WP_038483622	DNA topoisomerase I [Halomonas campaniensis].	27.92	394	218	17	77	452	296	641	1e-18	99.4
tr:G9EFA7_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.99	393	219	16	77	452	235	580	1e-18	99.4
rs:WP_005732652	MULTISPECIES: topoisomerase I [Pseudomonas syringae group genomosp. 2].	28.01	407	244	16	49	446	261	627	1e-18	99.4
rs:WP_041064938	DNA topoisomerase I [Thiolapillus brandeum].	26.89	424	257	16	46	452	232	619	1e-18	99.4
rs:WP_027349138	DNA topoisomerase I [Halotalea alkalilenta].	27.53	385	232	14	77	452	294	640	1e-18	99.4
rs:WP_031552739	DNA topoisomerase I [Parvularcula oceani].	27.66	441	257	14	44	452	224	634	1e-18	99.4
tr:D4K7I0_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.62	432	251	16	45	452	222	611	1e-18	99.0
rs:WP_048156986	DNA topoisomerase [Methanosarcina sp. Kolksee].	26.00	450	265	18	31	454	251	658	1e-18	99.4
rs:WP_005357832	DNA topoisomerase I [[Eubacterium] siraeum].	25.42	480	263	19	4	452	209	624	1e-18	99.0
rs:WP_022267008	DNA topoisomerase [Firmicutes bacterium CAG:449].	25.41	366	237	10	77	426	259	604	1e-18	99.0
rs:WP_037478091	hypothetical protein, partial [Sphingobium sp. ba1].	25.62	484	291	16	1	452	171	617	1e-18	99.4
rs:WP_008261370	DNA topoisomerase I [Brevundimonas sp. BAL3].	27.49	422	251	15	60	454	242	635	1e-18	99.4
tr:S5VI98_ENTFC	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:AGS77016.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AGS77016.1};	35.15	165	98	3	201	365	2	157	1e-18	96.3
rs:WP_033162674	DNA topoisomerase I [Sharpea azabuensis].	26.57	429	251	13	48	459	226	607	1e-18	99.0
rs:WP_023957456	DNA topoisomerase I [Paenibacillus sp. JCM 10914].	24.77	436	270	12	41	457	218	614	1e-18	99.0
rs:WP_024953298	DNA topoisomerase I [Cobetia crustatorum].	28.26	407	225	18	70	458	291	648	1e-18	99.4
rs:WP_020037415	hypothetical protein [gamma proteobacterium SCGC AAA168-P09].	24.89	442	251	17	29	452	252	630	1e-18	99.4
rs:WP_003226594	topoisomerase I [Pseudomonas fluorescens].	27.37	391	231	15	69	446	277	627	1e-18	99.4
rs:WP_012985514	DNA topoisomerase I [Listeria seeligeri].	24.94	429	249	17	50	452	227	608	1e-18	99.0
rs:WP_034648778	DNA topoisomerase I [Corynebacterium vitaeruminis].	27.18	379	221	11	31	384	249	597	1e-18	99.4
rs:WP_037406881	DNA topoisomerase I [Snodgrassella alvi].	25.00	436	255	13	43	452	227	616	1e-18	99.4
rs:WP_011643221	DNA topoisomerase I [Maricaulis maris].	28.08	438	254	14	43	452	225	629	1e-18	99.4
rs:WP_019827482	DNA topoisomerase I [Pseudomonas sp. CF149].	27.87	409	246	16	47	446	259	627	1e-18	99.4
rs:WP_022361564	GTP-sensing transcriptional pleiotropic repressor CodY [Bacteroides pectinophilus CAG:437].	24.55	444	271	14	36	457	213	614	1e-18	99.0
rs:WP_032907384	DNA topoisomerase I [Streptococcus sanguinis].	23.85	436	257	13	40	452	227	610	1e-18	99.0
rs:WP_011840645	DNA topoisomerase I [Rhodobacter sphaeroides].	27.33	439	261	14	41	454	223	628	1e-18	99.4
rs:WP_012506744	DNA topoisomerase I [Prosthecochloris aestuarii].	26.35	444	247	17	44	454	236	632	1e-18	99.4
rs:WP_005998667	DNA topoisomerase I [Desulfuromonas acetoxidans].	25.12	430	263	12	47	454	232	624	1e-18	99.4
rs:XP_007422502	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Python bivittatus].	24.49	441	253	16	40	453	263	650	1e-18	99.4
rs:WP_005913038	DNA topoisomerase I [Fusobacterium nucleatum].	27.40	354	205	11	40	377	220	537	1e-18	99.0
rs:WP_010389785	topoisomerase I [Pseudoalteromonas undina].	26.07	422	260	14	36	446	251	631	1e-18	99.4
tr:E6PFJ4_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CBH75230.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBH75230.1};	25.61	453	281	13	23	457	202	616	1e-18	99.0
rs:WP_036513036	DNA topoisomerase I [Oceanicaulis sp. HL-87].	27.14	420	252	12	60	454	243	633	1e-18	99.4
rs:WP_019563323	DNA topoisomerase I [Thioalkalivibrio sp. ALMg2].	28.65	370	204	10	36	384	233	563	1e-18	99.4
rs:WP_038661211	DNA topoisomerase I [Pseudomonas stutzeri].	25.12	422	266	12	42	452	253	635	1e-18	99.4
rs:WP_047201597	DNA topoisomerase [Streptococcus agalactiae].	27.59	348	216	10	57	399	261	577	1e-18	99.0
rs:WP_044323044	DNA topoisomerase I [Pseudomonas amygdali].	28.01	407	244	16	49	446	261	627	1e-18	99.4
rs:XP_005670970	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Sus scrofa].	24.29	457	265	17	25	453	111	514	1e-18	99.0
rs:WP_003446618	MULTISPECIES: topoisomerase I [Pseudomonas].	27.30	392	232	15	68	446	276	627	1e-18	99.4
tr:M3WMK3_FELCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.18	424	245	14	60	455	312	695	1e-18	99.4
rs:WP_021060176	Topoisomerase IA, partial [Halonotius sp. J07HN6].	25.64	433	257	14	45	454	260	650	1e-18	99.0
rs:WP_020031242	hypothetical protein [gamma proteobacterium SCGC AAA168-I18].	26.60	391	227	15	77	452	285	630	1e-18	99.4
rs:WP_038184057	DNA topoisomerase I [Viridibacillus arenosi].	24.24	429	272	12	40	452	217	608	1e-18	99.0
tr:A0A099VSN8_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.89	421	250	14	47	450	230	605	1e-18	99.0
rs:WP_006597227	DNA topoisomerase I [Streptococcus australis].	24.11	423	254	13	49	452	219	593	1e-18	99.0
rs:WP_019025494	MULTISPECIES: hypothetical protein [Thioalkalivibrio].	27.49	422	245	15	61	458	233	617	1e-18	99.0
rs:WP_043215225	DNA topoisomerase I [Pseudomonas putida].	25.69	397	249	13	77	459	263	627	1e-18	99.0
rs:WP_019242321	DNA topoisomerase I [Bacillus massilioanorexius].	23.84	432	266	14	47	457	224	613	1e-18	99.0
rs:WP_003106651	DNA topoisomerase III [Streptococcus parauberis].	27.44	379	228	13	30	398	231	572	1e-18	98.6
rs:WP_040480579	DNA topoisomerase I [Halomonas boliviensis].	27.99	393	219	16	77	452	296	641	1e-18	99.0
rs:WP_008928140	topoisomerase I [Alcanivorax hongdengensis].	25.06	399	249	12	60	446	279	639	1e-18	99.4
rs:WP_025977129	DNA topoisomerase I [Brevundimonas naejangsanensis].	26.82	425	249	15	60	454	242	634	1e-18	99.0
rs:WP_010406126	DNA topoisomerase I [Sphingomonas echinoides].	27.72	487	277	18	1	452	171	617	1e-18	99.0
rs:WP_032911974	DNA topoisomerase I [Streptococcus sanguinis].	23.85	436	257	13	40	452	227	610	1e-18	99.0
rs:WP_016998603	DNA topoisomerase I [Staphylococcus lentus].	27.25	400	223	17	76	452	253	607	1e-18	99.0
rs:WP_005928228	DNA topoisomerase I [Faecalibacterium prausnitzii].	26.62	432	251	16	45	452	222	611	1e-18	99.0
rs:WP_021890495	DNA topoisomerase [Succinatimonas sp. CAG:777].	26.67	405	241	12	47	439	248	608	1e-18	99.0
rs:XP_005054687	PREDICTED: DNA topoisomerase 3-alpha [Ficedula albicollis].	25.57	442	268	16	40	456	289	694	1e-18	99.4
rs:WP_006365751	DNA topoisomerase I [Chlorobium ferrooxidans].	26.88	439	241	16	47	450	235	628	1e-18	99.0
rs:WP_046859941	DNA topoisomerase I [Sedimenticola sp. SIP-G1].	27.21	419	246	17	60	458	245	624	1e-18	99.0
rs:WP_044111856	DNA topoisomerase I [Acinetobacter sp. MII].	28.04	321	191	10	40	356	268	552	1e-18	99.0
rs:WP_035409985	DNA topoisomerase I [Chromohalobacter israelensis].	29.01	393	227	17	70	452	293	643	1e-18	99.0
rs:WP_009181788	DNA topoisomerase I [Desulfovibrio sp. FW1012B].	25.24	416	251	12	54	452	232	604	1e-18	99.0
rs:WP_012548590	DNA topoisomerase I [Dictyoglomus thermophilum].	23.79	433	241	14	70	449	248	644	1e-18	99.0
rs:XP_012171189	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Bombus terrestris].	24.37	439	272	12	37	452	287	688	1e-18	99.4
rs:WP_009259245	DNA topoisomerase I [Lachnospiraceae bacterium 7_1_58FAA].	26.08	441	267	14	34	454	214	615	1e-18	99.0
rs:WP_024395842	DNA topoisomerase I [Streptococcus suis].	24.10	444	260	14	34	452	222	613	1e-18	99.0
rs:WP_009795914	MULTISPECIES: DNA topoisomerase I [Bacillus].	25.35	430	246	16	50	452	227	608	1e-18	99.0
rs:WP_023940227	DNA topoisomerase I [Streptococcus pseudopneumoniae].	24.45	409	236	14	66	452	254	611	1e-18	99.0
rs:WP_012289980	DNA topoisomerase III [Finegoldia magna].	28.40	324	200	10	79	399	270	564	1e-18	98.6
rs:WP_004417186	DNA topoisomerase I [Pseudomonas syringae].	28.57	413	238	18	47	446	259	627	1e-18	99.0
rs:WP_032846708	DNA topoisomerase I [Fusobacterium sp. CM22].	27.45	368	212	12	26	377	212	540	1e-18	99.0
rs:WP_042128949	DNA topoisomerase I [Paenibacillus sp. FSL R5-0345].	25.17	429	259	13	50	457	227	614	1e-18	99.0
rs:WP_045796399	DNA topoisomerase I [Acinetobacter indicus].	28.04	321	191	10	40	356	266	550	1e-18	99.0
rs:WP_047541122	DNA topoisomerase I [Pseudomonas simiae].	24.94	401	259	11	70	459	256	625	1e-18	98.6
rs:WP_041978506	hypothetical protein [Pyrinomonas methylaliphatogenes].	24.78	452	274	12	25	452	224	633	1e-18	99.0
rs:WP_029639161	DNA topoisomerase I [alpha proteobacterium Mf 1.05b.01].	27.63	438	241	14	58	458	241	639	1e-18	99.0
rs:WP_040195133	DNA topoisomerase I [Clostridium sp. CL-6].	26.93	427	247	14	47	452	226	608	1e-18	99.0
tr:F2BS11_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.85	436	257	13	40	452	230	613	1e-18	99.0
rs:WP_018949196	DNA topoisomerase I [Thioalkalivibrio sp. ALMg11].	28.65	370	204	10	36	384	233	563	1e-18	99.0
rs:WP_016625619	DNA topoisomerase I [Enterococcus faecalis].	25.81	399	239	15	77	457	255	614	1e-18	99.0
tr:E9FJZ9_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.76	425	251	14	50	452	244	617	1e-18	99.0
rs:WP_022481595	DNA topoisomerase [Clostridium sp. CAG:729].	25.90	390	233	13	77	450	281	630	1e-18	99.0
rs:WP_028954651	DNA topoisomerase I [Sulfitobacter sp. 20_GPM-1509m].	28.07	431	250	16	47	452	231	626	1e-18	99.0
rs:WP_037614931	DNA topoisomerase I [Streptococcus sinensis].	23.85	436	257	13	40	452	227	610	1e-18	98.6
rs:WP_012857987	DNA topoisomerase I [Sulfurospirillum deleyianum].	27.59	406	208	16	76	452	257	605	1e-18	98.6
rs:WP_039601790	DNA topoisomerase I [Pseudomonas putida].	27.32	410	247	13	47	446	258	626	1e-18	99.0
rs:WP_047275656	DNA topoisomerase I [Pseudomonas fluorescens].	27.64	416	246	16	42	446	256	627	1e-18	99.0
rs:WP_033917940	DNA topoisomerase I [Enterococcus faecalis].	24.37	439	272	17	34	452	211	609	1e-18	98.6
rs:WP_021630176	DNA topoisomerase I [Clostridium sp. ATCC BAA-442].	25.74	439	271	13	34	454	214	615	1e-18	99.0
rs:WP_028388168	DNA topoisomerase I [Legionella fairfieldensis].	25.37	469	289	16	3	452	195	621	1e-18	99.0
rs:XP_012321902	PREDICTED: DNA topoisomerase 3-beta-1 isoform X4 [Aotus nancymaae].	24.29	457	265	17	25	453	129	532	1e-18	98.6
rs:WP_027976116	DNA topoisomerase I [Streptococcus devriesei].	24.01	429	266	12	40	452	235	619	1e-18	98.6
rs:WP_013143479	DNA topoisomerase I [Staphylothermus hellenicus].	26.10	433	263	18	11	425	263	656	1e-18	98.6
rs:WP_005007267	DNA topoisomerase I [Acinetobacter bouvetii].	27.54	345	207	11	40	377	267	575	1e-18	99.0
rs:WP_029658312	DNA topoisomerase I [Streptococcus pneumoniae].	25.18	409	233	15	66	452	236	593	1e-18	98.6
rs:WP_021696001	DNA topoisomerase I [Brevundimonas abyssalis].	26.70	427	247	14	60	454	242	634	1e-18	99.0
rs:WP_004051361	DNA topoisomerase I [Halococcus morrhuae].	24.71	433	281	12	29	454	238	632	1e-18	99.0
rs:XP_012321903	PREDICTED: DNA topoisomerase 3-beta-1 isoform X5 [Aotus nancymaae].	24.29	457	265	17	25	453	111	514	1e-18	98.6
rs:WP_042762851	DNA topoisomerase I [Streptococcus sanguinis].	23.85	436	257	13	40	452	227	610	1e-18	98.6
rs:WP_016910752	DNA topoisomerase I [Staphylococcus vitulinus].	27.07	399	225	17	76	452	253	607	1e-18	98.6
rs:WP_005182090	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	28.04	321	191	10	40	356	266	550	1e-18	99.0
rs:WP_027915088	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	25.82	395	232	12	69	446	276	626	1e-18	99.0
tr:U1YAP5_ANEAE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.94	429	259	15	50	457	250	636	1e-18	98.6
tr:E7SBC1_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.11	423	254	13	49	452	247	621	1e-18	98.6
rs:WP_022757655	hypothetical protein [Butyrivibrio fibrisolvens].	25.71	389	240	16	77	449	280	635	1e-18	98.6
rs:WP_000179631	DNA topoisomerase I [Streptococcus pneumoniae].	24.69	409	235	14	66	452	254	611	1e-18	98.6
rs:WP_017174596	MULTISPECIES: DNA topoisomerase I [Bacteria].	24.00	425	262	14	47	452	224	606	1e-18	98.6
rs:WP_018127479	hypothetical protein [Balneola vulgaris].	28.46	390	212	13	41	398	251	605	1e-18	99.0
rs:WP_029178045	DNA topoisomerase I [Streptococcus suis].	24.88	422	251	12	50	452	239	613	1e-18	98.6
tr:J9Z7K0_LEPFM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.81	430	268	12	41	452	192	588	1e-18	98.6
tr:U7SSI8_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.17	368	213	12	26	377	209	537	1e-18	98.6
rs:WP_005553766	DNA topoisomerase I [Natronococcus amylolyticus].	24.41	422	268	14	45	454	251	633	1e-18	98.6
rs:WP_031586825	DNA topoisomerase I [Selenomonas bovis].	27.27	440	251	17	41	456	264	658	1e-18	98.6
rs:WP_002455421	DNA topoisomerase I [Staphylococcus hominis].	24.00	425	262	14	47	452	224	606	1e-18	98.6
rs:WP_040803059	DNA topoisomerase I [Streptococcus australis].	24.11	423	254	13	49	452	237	611	1e-18	98.6
rs:WP_000179654	DNA topoisomerase I [Streptococcus pseudopneumoniae].	24.69	409	235	14	66	452	254	611	1e-18	98.6
rs:WP_037925496	DNA topoisomerase I [Sulfitobacter pseudonitzschiae].	27.44	430	254	15	47	452	231	626	2e-18	99.0
rs:WP_003164641	DNA topoisomerase I [Brevundimonas diminuta].	26.53	426	249	15	60	454	242	634	2e-18	98.6
rs:WP_012313561	topoisomerase I [Pseudomonas putida].	27.32	410	247	13	47	446	258	626	2e-18	98.6
tr:F3UAY0_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.85	436	257	13	40	452	230	613	2e-18	98.6
rs:WP_043413119	DNA topoisomerase I [Mycobacterium rufum].	28.03	396	229	14	38	410	265	627	2e-18	99.0
rs:WP_040302418	DNA topoisomerase I [Aneurinibacillus aneurinilyticus].	24.94	429	259	15	50	457	227	613	2e-18	98.6
tr:X8HDT0_9FUSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.45	368	212	12	26	377	209	537	2e-18	98.6
tr:A0A0B5HKC5_9ARCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.70	421	264	12	47	453	252	633	2e-18	98.6
rs:WP_025242302	DNA topoisomerase I [Pseudomonas stutzeri].	25.69	401	242	13	69	452	274	635	2e-18	98.6
rs:WP_032884070	DNA topoisomerase I [Fusobacterium nucleatum].	27.17	368	213	12	26	377	212	540	2e-18	98.6
rs:WP_032878736	DNA topoisomerase I [Fusobacterium nucleatum].	26.90	368	214	12	26	377	209	537	2e-18	98.6
rs:WP_026882308	DNA topoisomerase I [Clostridium akagii].	25.06	435	261	16	41	454	220	610	2e-18	98.6
rs:WP_012971263	DNA topoisomerase I [Allochromatium vinosum].	26.73	434	250	15	44	452	230	620	2e-18	98.6
rs:WP_022257719	DNA topoisomerase [Faecalibacterium sp. CAG:82].	26.74	430	249	17	47	452	224	611	2e-18	98.6
rs:WP_002448837	DNA topoisomerase I [Staphylococcus hominis].	25.06	395	235	14	77	452	254	606	2e-18	98.6
tr:H0Y6W0_HUMAN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.51	457	264	17	25	453	42	445	2e-18	98.2
rs:XP_012321901	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Aotus nancymaae].	24.29	457	265	17	25	453	130	533	2e-18	98.6
rs:WP_041326775	DNA topoisomerase III, partial [Ruminococcus champanellensis].	31.13	212	138	5	37	246	227	432	2e-18	97.4
rs:WP_008082212	topoisomerase I [Pseudomonas sp. GM80].	27.37	391	231	15	69	446	277	627	2e-18	98.6
rs:XP_011247268	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Mus musculus].	26.07	445	260	16	40	455	230	634	2e-18	98.6
rs:WP_041772386	DNA topoisomerase [Leptospirillum ferriphilum].	25.81	430	268	12	41	452	228	624	2e-18	98.6
tr:G9WHS7_9LACT	SubName: Full=TrsI(TraI) family conjugation protein {ECO:0000313|EMBL:EHN58651.1};	34.08	179	108	4	221	397	17	187	2e-18	95.5
rs:WP_036593494	topoisomerase I, partial [Oenococcus kitaharae].	34.08	179	108	4	221	397	1	171	2e-18	95.1
tr:U1QZT7_9EURY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.34	452	274	17	40	454	256	676	2e-18	98.6
rs:WP_042492497	DNA topoisomerase I [Weissella hellenica].	26.13	444	255	19	34	452	242	637	2e-18	98.6
tr:Q5NCT0_MOUSE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.07	445	260	16	40	455	264	668	2e-18	98.6
rs:WP_016396514	DNA topoisomerase I [Lactobacillus delbrueckii].	26.79	433	245	17	43	452	164	547	2e-18	98.2
rs:WP_025084927	DNA topoisomerase I [Lactobacillus paralimentarius].	25.56	399	239	13	77	457	258	616	2e-18	98.6
rs:WP_000179662	DNA topoisomerase I [Streptococcus sp. M334].	23.76	425	251	14	50	452	238	611	2e-18	98.6
rs:WP_006148622	DNA topoisomerase I [Streptococcus infantis].	25.00	412	242	13	60	452	248	611	2e-18	98.6
rs:WP_038641989	DNA topoisomerase I [Pseudoalteromonas sp. OCN003].	26.84	354	212	10	43	384	256	574	2e-18	98.6
rs:WP_007816808	DNA topoisomerase I [Roseobacter sp. AzwK-3b].	26.90	435	253	15	47	454	231	627	2e-18	98.6
rs:XP_010717866	PREDICTED: DNA topoisomerase 3-alpha [Meleagris gallopavo].	25.84	445	265	16	39	456	290	696	2e-18	98.6
rs:WP_036982852	DNA topoisomerase I [Pseudoalteromonas sp. SCSIO_11900].	25.83	422	261	14	36	446	251	631	2e-18	98.6
rs:WP_018061048	hypothetical protein, partial [Caulobacter sp. JGI 0001013-O16].	26.73	434	239	16	51	452	35	421	2e-18	97.1
rs:WP_022311841	DNA topoisomerase [Clostridium sp. CAG:91].	25.29	427	258	14	47	454	226	610	2e-18	98.6
rs:WP_041285335	DNA topoisomerase I, partial [Desulfotomaculum gibsoniae].	24.60	443	249	13	61	450	242	652	2e-18	98.6
rs:WP_022233276	DNA topoisomerase III [Bacteroides sp. CAG:443].	24.06	399	267	10	5	394	204	575	2e-18	98.2
tr:A0A094WEU5_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.12	430	271	12	41	452	192	588	2e-18	98.6
rs:XP_006993093	PREDICTED: DNA topoisomerase 3-beta-1 [Peromyscus maniculatus bairdii].	24.07	457	266	17	25	453	247	650	2e-18	98.6
rs:WP_029916231	DNA topoisomerase I [Caulobacter sp. UNC358MFTsu5.1].	26.42	424	243	15	61	452	243	629	2e-18	98.6
rs:WP_010784903	DNA topoisomerase 1 [Enterococcus faecalis].	24.37	439	272	17	34	452	211	609	2e-18	98.6
rs:WP_023519488	DNA topoisomerase I [Enterococcus mundtii].	24.21	442	279	14	34	457	211	614	2e-18	98.6
rs:WP_025167376	DNA topoisomerase I [Pseudomonas taeanensis].	26.62	402	239	14	68	452	275	637	2e-18	98.6
rs:WP_014103479	DNA topoisomerase I [Micavibrio aeruginosavorus].	26.07	445	257	18	45	454	231	638	2e-18	98.6
rs:WP_027434871	DNA topoisomerase I [Lachnospiraceae bacterium AB2028].	27.19	445	249	18	40	454	218	617	2e-18	98.6
rs:WP_006556648	DNA topoisomerase I [Veillonella ratti].	25.48	420	247	13	56	454	291	665	2e-18	98.6
rs:WP_009723521	topoisomerase I [Halomonas sp. TD01].	27.92	394	218	17	77	452	296	641	2e-18	98.6
rs:XP_012321900	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Aotus nancymaae].	24.29	457	265	17	25	453	247	650	2e-18	98.6
rs:WP_039675625	DNA topoisomerase I [Sulfurospirillum sp. MES].	27.32	399	218	15	76	452	257	605	2e-18	98.2
rs:WP_018144652	DNA topoisomerase I [Thioalkalivibrio sp. AKL6].	28.65	370	204	10	36	384	233	563	2e-18	98.6
rs:WP_046210735	DNA topoisomerase I [Nautella sp. ECSMB14104].	26.41	462	253	17	41	454	225	647	2e-18	98.6
rs:WP_027229115	DNA topoisomerase I [Legionella pneumophila].	27.06	436	241	18	46	452	234	621	2e-18	98.6
rs:WP_015191856	DNA topoisomerase I [Stanieria cyanosphaera].	26.05	357	223	9	41	387	249	574	2e-18	98.6
rs:WP_014848241	DNA topoisomerase I [Zymomonas mobilis].	26.09	437	262	14	41	452	222	622	2e-18	99.0
rs:XP_003359220	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Sus scrofa].	24.29	457	265	17	25	453	247	650	2e-18	98.6
rs:XP_012321898	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Aotus nancymaae].	24.29	457	265	17	25	453	248	651	2e-18	98.6
rs:WP_047186038	DNA topoisomerase I [Bacilli bacterium VT-13-104].	25.42	421	248	16	60	457	236	613	2e-18	98.2
rs:WP_024723336	DNA topoisomerase I [Clostridiales bacterium VE202-03].	26.08	441	267	14	34	454	214	615	2e-18	98.6
rs:WP_013961209	DNA topoisomerase I [Roseobacter litoralis].	28.51	435	244	19	47	452	231	627	2e-18	98.6
tr:Q8CDI8_MOUSE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.42	424	244	15	60	455	195	578	2e-18	98.6
rs:WP_014970695	DNA topoisomerase I [Exiguobacterium antarcticum].	24.42	475	266	16	34	450	210	649	2e-18	98.2
rs:WP_015222548	DNA topoisomerase I [Cyanobacterium stanieri].	24.93	357	232	7	41	391	249	575	2e-18	98.6
rs:WP_018167332	DNA topoisomerase I [Streptococcus minor].	23.62	436	272	12	34	452	226	617	2e-18	98.2
rs:WP_039707018	DNA topoisomerase I, partial [marine actinobacterium MedAcidi-G3].	28.31	332	179	12	35	342	234	530	2e-18	98.2
tr:A0A093QKD6_9PASS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.78	450	263	17	39	456	228	638	2e-18	98.6
rs:WP_008163680	DNA topoisomerase I [Natronorubrum sulfidifaciens].	23.70	422	280	11	40	454	248	634	2e-18	98.6
tr:X8IE43_9FUSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.23	366	219	10	26	377	209	537	2e-18	98.6
rs:WP_035253003	DNA topoisomerase I [Actibacterium atlanticum].	28.57	420	236	15	60	452	244	626	2e-18	98.6
rs:WP_028835835	MULTISPECIES: DNA topoisomerase I [Pseudoalteromonas].	25.83	422	261	14	36	446	251	631	2e-18	98.6
rs:WP_045490136	DNA topoisomerase I [Candidatus Liberibacter asiaticus].	25.17	449	251	17	47	452	230	636	2e-18	98.6
rs:WP_027601459	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	27.61	402	229	14	62	446	269	625	2e-18	98.6
rs:WP_032885958	DNA topoisomerase I, partial [Fusobacterium nucleatum].	26.23	366	219	10	26	377	212	540	2e-18	98.2
rs:WP_004222574	hypothetical protein [Bifidobacterium pseudocatenulatum].	33.06	245	136	6	160	377	2	245	2e-18	96.7
rs:WP_021774356	DNA topoisomerase I [Oribacterium sp. oral taxon 078].	24.36	427	263	13	47	454	226	611	2e-18	98.2
rs:WP_017430159	topoisomerase I [Halomonas jeotgali].	28.32	399	222	18	70	452	291	641	2e-18	98.6
rs:WP_003626499	DNA topoisomerase I [Lactobacillus helveticus].	24.94	429	264	12	45	457	236	622	2e-18	98.2
rs:WP_025283551	DNA topoisomerase I [Lactobacillus helveticus].	24.94	429	264	12	45	457	236	622	2e-18	98.2
rs:WP_029090988	DNA topoisomerase I [Brochothrix thermosphacta].	23.88	448	273	16	29	452	205	608	2e-18	98.2
rs:WP_014758637	DNA topoisomerase I [Thermoanaerobacterium aotearoense].	27.05	451	251	18	28	454	213	609	2e-18	98.2
sp:TOP3A_MOUSE	RecName: Full=DNA topoisomerase 3-alpha; EC=5.99.1.2; AltName: Full=DNA topoisomerase III alpha;	26.42	424	244	15	60	455	310	693	2e-18	98.6
tr:R4KF98_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952}; Flags: Precursor;	24.60	443	249	13	61	450	239	649	2e-18	98.2
rs:XP_009005663	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Callithrix jacchus].	24.29	457	265	17	25	453	111	514	2e-18	98.2
rs:WP_013854176	DNA topoisomerase I [Lactobacillus kefiranofaciens].	24.94	429	264	12	45	457	241	627	2e-18	98.2
rs:XP_009005657	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Callithrix jacchus].	24.29	457	265	17	25	453	123	526	2e-18	98.2
rs:WP_014918887	DNA topoisomerase I [Lactobacillus helveticus].	24.94	429	264	12	45	457	236	622	2e-18	98.2
rs:WP_012778525	DNA topoisomerase I [Candidatus Liberibacter asiaticus].	25.17	449	251	17	47	452	230	636	2e-18	98.6
rs:WP_003302513	DNA topoisomerase I subunit omega, partial [Pseudomonas stutzeri].	24.88	422	267	12	42	452	212	594	2e-18	98.6
tr:D4LEK1_RUMC1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.13	212	138	5	37	246	227	432	2e-18	97.4
rs:WP_027826532	DNA topoisomerase I [Lactobacillus saerimneri].	25.82	426	243	18	55	457	243	618	2e-18	98.2
rs:WP_042700233	DNA topoisomerase I [Methanocorpusculum bavaricum].	24.89	450	273	17	18	449	216	618	2e-18	98.6
rs:XP_007536504	PREDICTED: DNA topoisomerase 3-beta-1 [Erinaceus europaeus].	23.81	441	256	16	40	453	263	650	2e-18	98.6
rs:WP_040423432	DNA topoisomerase I [Corynebacterium genitalium].	26.40	356	209	10	47	386	263	581	2e-18	98.6
rs:XP_006161709	PREDICTED: DNA topoisomerase 3-alpha [Tupaia chinensis].	26.18	424	245	14	60	455	310	693	2e-18	98.6
rs:WP_013079883	DNA topoisomerase I [Caulobacter segnis].	27.53	425	234	18	62	452	245	629	2e-18	98.6
rs:WP_004978972	DNA topoisomerase I [Acinetobacter johnsonii].	26.93	427	255	19	40	452	268	651	2e-18	98.6
rs:WP_027970598	DNA topoisomerase I [Streptococcus castoreus].	23.62	453	281	12	19	452	219	625	2e-18	98.2
rs:WP_024894350	DNA topoisomerase I [Acidithiobacillus thiooxidans].	28.92	408	225	18	70	454	257	622	2e-18	98.2
rs:WP_004269684	DNA topoisomerase I [Streptococcus mitis].	24.57	407	238	14	66	452	254	611	2e-18	98.2
rs:XP_005339524	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Ictidomys tridecemlineatus].	25.39	445	263	15	40	455	289	693	2e-18	98.6
rs:WP_042189457	DNA topoisomerase I [Paenibacillus sp. FSL H7-0737].	25.17	429	259	13	50	457	227	614	2e-18	98.2
rs:WP_016185340	DNA topoisomerase I [Enterococcus sulfureus].	25.73	412	239	13	69	457	247	614	2e-18	98.2
tr:Q3V3P1_MOUSE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.07	445	260	16	40	455	289	693	2e-18	98.6
tr:C6XEP4_METGS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.34	407	260	14	60	458	227	589	2e-18	97.8
rs:WP_024962665	DNA topoisomerase I [Campylobacter ureolyticus].	25.83	422	247	13	47	450	224	597	2e-18	98.2
tr:J7CFA4_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJY32177.1}; Flags: Fragment;	36.48	159	92	3	207	365	2	151	2e-18	95.5
rs:WP_036080422	DNA topoisomerase [Leptospirillum ferriphilum].	25.12	430	271	12	41	452	218	614	2e-18	98.2
rs:WP_032837410	DNA topoisomerase I [Fusobacterium sp. CM1].	26.23	366	219	10	26	377	212	540	2e-18	98.2
rs:WP_047293077	DNA topoisomerase I [Pseudomonas fluorescens].	27.64	416	246	16	42	446	256	627	2e-18	98.2
rs:WP_047274029	DNA topoisomerase I [Pseudomonas fluorescens].	27.64	416	246	16	42	446	256	627	2e-18	98.2
rs:WP_043868917	DNA topoisomerase I [Celeribacter indicus].	28.17	458	248	20	41	454	225	645	2e-18	98.2
tr:Q3EKS2_BACTI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.74	163	104	3	36	196	244	404	2e-18	96.7
rs:WP_046814120	DNA topoisomerase I [Lactobacillus helveticus].	24.94	429	264	12	45	457	236	622	2e-18	98.2
rs:WP_002838175	DNA topoisomerase I [Finegoldia magna].	23.97	484	287	15	1	452	171	605	2e-18	98.2
rs:WP_017499589	DNA topoisomerase I [alpha proteobacterium LLX12A].	25.98	485	288	18	1	452	171	617	2e-18	98.2
rs:XP_002743624	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Callithrix jacchus].	24.29	457	265	17	25	453	247	650	2e-18	98.2
rs:WP_031935128	DNA topoisomerase I [Candidatus Liberibacter asiaticus].	25.17	449	251	17	47	452	236	642	2e-18	98.2
rs:WP_023061818	DNA topoisomerase [Lactobacillus helveticus].	24.94	429	264	12	45	457	236	622	2e-18	98.2
tr:F0FTK4_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.65	430	248	14	46	452	237	613	2e-18	98.2
tr:F2CD39_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.65	430	248	14	46	452	237	613	2e-18	98.2
rs:WP_044759764	DNA topoisomerase I [Streptococcus suis].	23.52	421	258	11	50	452	239	613	2e-18	98.2
tr:A0A0E4H879_9STRE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:CQR25143.1};	27.62	344	215	10	60	399	264	577	2e-18	97.8
rs:WP_031572692	DNA topoisomerase I [Acidithiobacillus thiooxidans].	28.92	408	225	18	70	454	257	622	2e-18	98.2
rs:WP_009731066	DNA topoisomerase 1 [Streptococcus sp. F0442].	23.88	423	255	13	49	452	235	609	2e-18	98.2
rs:WP_018879677	DNA topoisomerase I [Thioalkalivibrio sp. ALE9].	28.69	359	200	9	36	377	233	552	2e-18	98.2
rs:WP_033685170	DNA topoisomerase I [Streptococcus mitis].	23.76	425	251	14	50	452	238	611	2e-18	98.2
rs:WP_022179515	DNA topoisomerase [Firmicutes bacterium CAG:582].	24.05	474	287	16	1	450	170	594	2e-18	98.2
rs:WP_014563693	DNA topoisomerase I [Lactobacillus helveticus].	24.94	429	264	12	45	457	236	622	2e-18	98.2
rs:WP_044781401	DNA topoisomerase I [Streptococcus suis].	24.64	422	252	12	50	452	239	613	2e-18	98.2
tr:D6WYH2_TRICA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.60	445	264	11	40	451	256	657	2e-18	98.2
rs:WP_019558996	DNA topoisomerase I [Thioalkalivibrio sp. ALE12].	28.69	359	200	9	36	377	233	552	2e-18	98.2
rs:WP_040429651	DNA topoisomerase I, partial [Acidithiobacillus thiooxidans].	28.92	408	225	18	70	454	257	622	2e-18	98.2
rs:WP_013524908	DNA topoisomerase I [Thermovibrio ammonificans].	29.03	341	176	11	58	377	225	520	2e-18	97.8
rs:WP_025801906	DNA topoisomerase I [Campylobacter sp. CIT045].	25.94	424	245	16	47	450	224	598	2e-18	98.2
rs:WP_040929149	DNA topoisomerase I [Nosocomiicoccus sp. NP2].	24.25	433	272	12	41	457	219	611	2e-18	98.2
rs:WP_010503653	DNA topoisomerase I subunit omega [Gluconobacter frateurii].	26.29	426	247	17	60	452	244	635	2e-18	98.2
rs:WP_035557252	DNA topoisomerase I [Halomonas sp. KO116].	27.51	389	226	14	77	452	296	641	2e-18	98.2
rs:WP_019023224	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	28.69	359	200	9	36	377	233	552	2e-18	98.2
rs:WP_002839112	DNA topoisomerase I [Finegoldia magna].	23.97	484	287	15	1	452	171	605	2e-18	98.2
tr:D7WBB2_9CORY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.40	356	209	10	47	386	280	598	2e-18	98.2
rs:WP_037597010	DNA topoisomerase I [Streptococcus sp. AS20].	23.74	438	260	14	39	452	223	610	2e-18	98.2
rs:WP_005780640	topoisomerase I [Pseudomonas amygdali].	27.76	407	245	16	49	446	261	627	2e-18	98.2
rs:XP_973578	PREDICTED: DNA topoisomerase 3-alpha [Tribolium castaneum].	23.60	445	264	11	40	451	281	682	2e-18	98.2
rs:WP_023394812	DNA topoisomerase I [Candidatus Halobonum tyrrellensis].	22.17	460	268	14	30	454	246	650	2e-18	98.2
rs:WP_019593470	DNA topoisomerase I [Thioalkalivibrio sp. ALM2T].	28.65	370	204	10	36	384	233	563	2e-18	98.2
rs:WP_018878614	DNA topoisomerase I [Thioalkalivibrio sp. ALE28].	28.69	359	200	9	36	377	233	552	2e-18	98.2
rs:WP_032909544	DNA topoisomerase I [Streptococcus sanguinis].	24.65	430	248	14	46	452	234	610	2e-18	97.8
rs:WP_032908811	DNA topoisomerase I [Streptococcus sanguinis].	24.65	430	248	14	46	452	234	610	2e-18	97.8
rs:XP_005350344	PREDICTED: DNA topoisomerase 3-alpha [Microtus ochrogaster].	26.18	424	245	14	60	455	205	588	2e-18	98.2
rs:WP_026696251	DNA topoisomerase I [Bacillus chagannorensis].	25.75	466	270	21	18	452	187	607	2e-18	97.8
rs:WP_027222752	DNA topoisomerase I [Legionella pneumophila].	27.58	417	224	18	65	452	254	621	2e-18	98.2
rs:XP_005870226	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Myotis brandtii].	26.00	427	244	14	60	456	259	643	2e-18	98.2
rs:WP_008026503	DNA topoisomerase III [Bacteroides xylanisolvens].	24.24	330	219	8	61	385	263	566	2e-18	97.8
rs:WP_006906309	DNA topoisomerase I [Shuttleworthia satelles].	24.47	425	264	10	50	457	230	614	2e-18	97.8
rs:WP_023593058	DNA topoisomerase I [Zymomonas mobilis].	26.09	437	262	14	41	452	222	622	2e-18	98.2
tr:F3GFX9_PSESJ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.63	409	247	16	47	446	259	627	2e-18	98.2
rs:WP_005744458	topoisomerase I [Pseudomonas amygdali].	27.76	407	245	16	49	446	261	627	2e-18	98.2
rs:WP_012370758	DNA topoisomerase I [Exiguobacterium sibiricum].	24.42	475	266	16	34	450	210	649	2e-18	97.8
tr:B6AM76_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.58	430	269	13	41	452	269	665	2e-18	98.2
rs:WP_038541104	DNA topoisomerase I [Bacillus sp. X1(2014)].	24.76	420	250	15	60	457	239	614	2e-18	97.8
rs:WP_047242530	DNA topoisomerase I [Enterococcus cecorum].	24.61	447	271	19	34	457	211	614	2e-18	97.8
rs:WP_006942643	DNA topoisomerase I [Megasphaera micronuciformis].	26.46	446	244	20	40	452	269	663	2e-18	98.2
tr:F3EUA5_PSEA0	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	27.76	407	245	16	49	446	126	492	2e-18	98.2
tr:F5W1Z7_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	412	242	13	60	452	201	564	2e-18	97.8
rs:WP_004656891	topoisomerase I [Pseudomonas savastanoi].	27.76	407	245	16	49	446	261	627	2e-18	98.2
rs:WP_022421259	DNA topoisomerase [Clostridium sp. CAG:307].	26.05	430	255	15	37	450	210	592	2e-18	98.2
rs:XP_005339523	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Ictidomys tridecemlineatus].	25.39	445	263	15	40	455	289	693	2e-18	98.2
rs:WP_012983639	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	28.69	359	200	9	36	377	233	552	2e-18	98.2
rs:WP_018084360	hypothetical protein [Desulfurispora thermophila].	24.60	439	276	11	36	457	214	614	2e-18	97.8
rs:WP_029039839	DNA topoisomerase I [Cucumibacter marinus].	26.32	475	270	17	22	452	193	631	2e-18	98.2
rs:WP_034842450	DNA topoisomerase I [[Clostridium] cellulosi].	25.69	432	256	15	47	454	225	615	2e-18	97.8
rs:WP_036622237	DNA topoisomerase I [Paenibacillus macerans].	25.81	430	256	16	50	457	227	615	2e-18	97.8
tr:A0A091PE50_HALAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.84	445	265	16	39	456	270	676	2e-18	98.2
rs:WP_031943336	Top: DNA topoisomerase [uncultured bacterium].	26.41	409	240	16	61	455	231	592	2e-18	97.8
rs:WP_024405688	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	2e-18	97.8
rs:WP_036747808	DNA topoisomerase I [Peptococcaceae bacterium SCADC1_2_3].	26.21	412	250	15	65	457	242	618	2e-18	97.8
rs:WP_002841675	DNA topoisomerase I [Finegoldia magna].	23.97	484	287	15	1	452	171	605	2e-18	97.8
rs:WP_035308752	DNA topoisomerase I [Brevundimonas sp. EAKA].	27.49	422	251	15	60	454	242	635	2e-18	98.2
rs:WP_029808434	DNA topoisomerase I [Vibrio parahaemolyticus].	26.47	442	258	18	35	459	207	598	2e-18	97.8
rs:WP_019584255	DNA topoisomerase I [Thioalkalivibrio sp. ALE16].	28.69	359	200	9	36	377	233	552	2e-18	98.2
rs:WP_019741898	topoisomerase I, partial [Pseudomonas savastanoi].	27.76	407	245	16	49	446	127	493	3e-18	97.8
rs:WP_020278186	DNA topoisomerase I [Geobacillus kaustophilus].	23.82	487	298	16	1	457	170	613	3e-18	97.8
rs:WP_016765407	DNA topoisomerase I [Bacillus megaterium].	24.18	488	295	21	1	457	170	613	3e-18	97.8
rs:XP_009919078	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Haliaeetus albicilla].	25.84	445	265	16	39	456	212	618	3e-18	98.2
rs:WP_009672956	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	26.36	330	220	8	54	377	252	564	3e-18	97.8
gp:CP008874_633	DNA topoisomerase I [Halanaeroarchaeum sulfurireducens]	23.75	379	241	11	86	454	292	632	3e-18	98.2
tr:A0A077ZCG1_TRITR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.97	466	241	22	39	451	245	659	3e-18	98.2
rs:WP_018876614	DNA topoisomerase I [Thioalkalivibrio sp. ALE31].	28.69	359	200	9	36	377	233	552	3e-18	98.2
rs:WP_009330770	MULTISPECIES: DNA topoisomerase I [Bacillus].	25.45	448	266	19	34	457	210	613	3e-18	97.8
rs:WP_015359063	DNA topoisomerase 1 [[Clostridium] stercorarium].	25.69	432	256	15	47	454	225	615	3e-18	97.8
rs:XP_009919077	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Haliaeetus albicilla].	25.84	445	265	16	39	456	276	682	3e-18	98.2
rs:WP_042223781	DNA topoisomerase I [Oceanobacillus manasiensis].	24.88	418	254	13	60	457	237	614	3e-18	97.8
tr:V9QQE9_9PSED	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.47	428	273	15	46	459	243	638	3e-18	97.8
rs:WP_025167044	DNA topoisomerase I [Pseudomonas taeanensis].	24.32	403	259	11	70	459	256	625	3e-18	97.8
rs:WP_044875067	DNA topoisomerase I [Pseudomonas sp. LFM046].	26.09	391	238	12	68	446	274	625	3e-18	98.2
rs:WP_032088847	DNA topoisomerase I [Bacillus aquimaris].	25.49	459	266	20	27	457	203	613	3e-18	97.8
rs:WP_003014956	DNA topoisomerase I [Streptococcus parasanguinis].	23.46	422	258	12	49	452	237	611	3e-18	97.8
rs:WP_017506494	DNA topoisomerase I [alpha proteobacterium L41A].	26.82	425	250	14	60	454	242	635	3e-18	98.2
rs:WP_035340555	DNA topoisomerase I [Bacillus hemicellulosilyticus].	24.76	424	256	14	50	452	227	608	3e-18	97.8
tr:G9YWW3_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.85	441	268	14	34	454	209	610	3e-18	97.8
rs:WP_021444488	topoisomerase I [Pseudomonas sp. EGD-AK9].	26.46	412	248	15	47	446	257	625	3e-18	98.2
rs:WP_015738598	DNA topoisomerase I [Ammonifex degensii].	24.43	438	248	12	61	449	238	641	3e-18	97.8
rs:WP_011534822	topoisomerase I [Pseudomonas entomophila].	26.96	408	251	13	47	446	258	626	3e-18	98.2
rs:XP_005834439	hypothetical protein GUITHDRAFT_69656 [Guillardia theta CCMP2712].	24.37	394	248	13	39	410	261	626	3e-18	97.8
tr:A0A098EKZ4_9BACL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.17	428	246	18	49	452	226	607	3e-18	97.8
rs:WP_009554367	DNA topoisomerase I [Lactobacillus saerimneri].	25.82	426	243	18	55	457	243	618	3e-18	97.8
tr:I3MP50_SPETR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.39	445	263	15	40	455	289	693	3e-18	98.2
rs:WP_017942609	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	28.69	359	200	9	36	377	233	552	3e-18	97.8
rs:WP_003427121	DNA topoisomerase I subunit omega [Pseudomonas syringae].	28.33	413	239	18	47	446	259	627	3e-18	97.8
tr:F7A1S4_XENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.38	457	270	16	27	452	276	692	3e-18	98.2
rs:XP_008840420	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Nannospalax galili].	24.14	464	269	18	18	453	237	645	3e-18	97.8
rs:WP_018993132	DNA topoisomerase I [Thioalkalivibrio sp. ARh4].	29.18	329	180	8	36	350	250	539	3e-18	97.8
rs:WP_013405856	DNA topoisomerase I [Halanaerobium hydrogeniformans].	27.46	448	248	18	35	456	214	610	3e-18	97.8
rs:WP_013084804	DNA topoisomerase I [Bacillus megaterium].	24.18	488	295	21	1	457	170	613	3e-18	97.8
rs:WP_018865472	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	28.69	359	200	9	36	377	233	552	3e-18	97.8
rs:WP_013881179	DNA topoisomerase I [Halopiger xanaduensis].	23.51	404	262	12	60	454	267	632	3e-18	97.8
rs:WP_017639782	topoisomerase I [Pseudomonas sp. 313].	27.36	402	230	14	62	446	269	625	3e-18	97.8
rs:XP_008060812	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Tarsius syrichta].	25.17	445	264	15	40	455	289	693	3e-18	98.2
rs:WP_014779492	DNA topoisomerase I [Thiocystis violascens].	26.68	431	254	16	44	452	230	620	3e-18	97.8
tr:D4IVN0_BUTFI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.30	442	280	12	36	457	213	615	3e-18	97.8
rs:WP_043518096	DNA topoisomerase I [Halomonas sp. BC04].	27.90	405	228	17	70	458	291	647	3e-18	97.8
tr:L8YCR4_TUPCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.18	424	245	14	60	455	290	673	3e-18	98.2
rs:WP_022846308	DNA topoisomerase I [Desulfurobacterium sp. TC5-1].	25.93	428	249	15	43	449	227	607	3e-18	97.8
rs:XP_005636690	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Canis lupus familiaris].	23.81	441	256	16	40	453	263	650	3e-18	97.8
rs:XP_007091146	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Panthera tigris altaica].	23.81	441	256	16	40	453	238	625	3e-18	97.8
rs:XP_006938802	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Felis catus].	23.81	441	256	16	40	453	238	625	3e-18	97.8
rs:WP_034047566	DNA topoisomerase I [Pseudomonas aeruginosa].	26.03	438	257	17	36	459	213	597	3e-18	97.8
rs:WP_018993201	DNA topoisomerase I [Thioalkalivibrio sp. ALgr1].	28.69	359	200	9	36	377	233	552	3e-18	97.8
rs:WP_044556338	DNA topoisomerase I [Shewanella piezotolerans].	26.25	419	251	13	42	446	257	631	3e-18	97.8
rs:WP_033585366	DNA topoisomerase I [Streptococcus sp. SR1].	24.09	411	247	12	60	452	248	611	3e-18	97.8
rs:WP_004636185	DNA topoisomerase I [Dolosigranulum pigrum].	24.07	432	268	12	43	457	222	610	3e-18	97.8
rs:WP_036579214	DNA topoisomerase I [Paenibacillus darwinianus].	25.95	420	245	14	61	457	238	614	3e-18	97.8
rs:XP_007091145	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Panthera tigris altaica].	23.81	441	256	16	40	453	263	650	3e-18	97.8
rs:WP_042317180	DNA topoisomerase III, partial [Desulfotomaculum acetoxidans].	33.95	162	101	2	224	385	2	157	3e-18	95.5
rs:WP_024662799	DNA topoisomerase I [Pseudomonas syringae].	28.33	413	239	18	47	446	259	627	3e-18	97.8
rs:WP_010197905	DNA topoisomerase I, partial [Pseudomonas amygdali].	27.76	407	245	16	49	446	123	489	3e-18	97.8
rs:WP_013058887	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.18	488	295	21	1	457	170	613	3e-18	97.8
rs:WP_046653556	DNA topoisomerase I [Brevundimonas diminuta].	26.76	426	248	15	60	454	242	634	3e-18	97.8
rs:WP_005682871	DNA topoisomerase III [Bacteroides caccae].	27.02	322	206	7	68	385	266	562	3e-18	97.4
rs:WP_009340934	DNA topoisomerase I [Afipia sp. 1NLS2].	27.31	432	244	15	59	454	240	637	3e-18	97.8
rs:XP_008060813	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Tarsius syrichta].	25.17	445	264	15	40	455	194	598	3e-18	97.8
rs:XP_009436167	PREDICTED: DNA topoisomerase 3-beta-1 isoform X5 [Pan troglodytes].	24.51	457	264	17	25	453	247	650	3e-18	97.8
rs:WP_013480650	DNA topoisomerase I [Asticcacaulis excentricus].	26.20	397	232	12	86	454	268	631	3e-18	97.8
rs:WP_031694571	DNA topoisomerase I, partial [Listeria monocytogenes].	25.98	408	229	17	71	452	7	367	3e-18	96.7
rs:WP_022299282	DNA topoisomerase [Clostridium sp. CAG:964].	24.84	459	254	17	47	449	225	648	3e-18	97.8
rs:WP_016568498	DNA topoisomerase I [Pseudomonas syringae].	28.33	413	239	18	47	446	259	627	3e-18	97.8
rs:XP_008840414	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Nannospalax galili].	24.07	457	266	17	25	453	247	650	3e-18	97.8
rs:WP_007049396	DNA topoisomerase I [Anaerofustis stercorihominis].	24.56	456	257	15	47	449	226	647	3e-18	97.8
rs:WP_023944543	DNA topoisomerase 1 [Gluconobacter frateurii].	26.06	426	248	17	60	452	244	635	3e-18	97.8
rs:WP_005976360	DNA topoisomerase I [Fusobacterium ulcerans].	26.73	333	193	11	60	377	235	531	3e-18	97.8
rs:WP_029957349	hypothetical protein, partial [Acetothermia bacterium SCGC AAA255-C06].	24.59	427	259	13	45	452	227	609	3e-18	97.8
rs:XP_005840332	hypothetical protein GUITHDRAFT_64354, partial [Guillardia theta CCMP2712].	26.32	342	212	10	39	370	249	560	3e-18	97.8
rs:WP_012535748	DNA topoisomerase I [Acidithiobacillus ferrooxidans].	29.06	413	218	19	70	454	257	622	3e-18	97.8
rs:XP_005017065	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Anas platyrhynchos].	25.62	445	266	16	39	456	290	696	3e-18	97.8
rs:WP_031943451	DNA topoisomerase [uncultured bacterium].	26.16	409	241	16	61	455	231	592	3e-18	97.4
rs:XP_004276082	PREDICTED: DNA topoisomerase 3-beta-1 [Orcinus orca].	24.04	441	255	16	40	453	263	650	3e-18	97.8
rs:XP_011286220	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Felis catus].	23.81	441	256	16	40	453	263	650	3e-18	97.8
rs:WP_029689622	DNA topoisomerase I [Streptococcus infantis].	25.00	412	242	13	60	452	231	594	3e-18	97.8
rs:WP_039997963	DNA topoisomerase I [Flavonifractor plautii].	25.85	441	268	14	34	454	214	615	3e-18	97.8
rs:XP_005870225	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Myotis brandtii].	26.00	427	244	14	60	456	310	694	3e-18	97.8
tr:F3IVS0_PSEAP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	28.47	411	237	18	49	446	123	489	3e-18	97.8
rs:XP_009894971	PREDICTED: DNA topoisomerase 3-alpha [Picoides pubescens].	25.84	445	265	16	39	456	290	696	3e-18	97.8
rs:WP_008193600	DNA topoisomerase I [Labrenzia alexandrii].	27.73	422	233	17	70	452	253	641	3e-18	97.8
rs:WP_003167051	DNA topoisomerase I [Brevundimonas diminuta].	26.53	426	249	15	60	454	242	634	3e-18	97.8
rs:WP_034419954	DNA topoisomerase I [Clostridiales bacterium DRI-13].	23.24	469	290	15	18	457	190	617	3e-18	97.8
rs:WP_023462771	DNA topoisomerase I [Asticcacaulis sp. YBE204].	27.30	403	220	17	86	454	268	631	3e-18	97.8
tr:B6FVP8_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	29.23	260	148	10	47	283	254	500	3e-18	97.1
rs:WP_008697687	DNA topoisomerase I [Fusobacterium ulcerans].	25.46	377	219	12	60	410	235	575	3e-18	97.8
rs:XP_010568690	PREDICTED: DNA topoisomerase 3-alpha [Haliaeetus leucocephalus].	25.84	445	265	16	39	456	284	690	3e-18	97.8
rs:WP_005935543	DNA topoisomerase I [Faecalibacterium prausnitzii].	26.58	444	257	18	36	452	210	611	3e-18	97.4
rs:WP_035081584	DNA topoisomerase I [Caulobacter henricii].	26.35	444	258	15	41	452	223	629	3e-18	97.8
rs:XP_005636691	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Canis lupus familiaris].	23.85	436	248	16	40	453	263	636	3e-18	97.8
rs:XP_012563421	PREDICTED: DNA topoisomerase 3-alpha-like [Hydra vulgaris].	24.89	446	262	14	39	452	263	667	3e-18	97.8
rs:XP_004918127	PREDICTED: DNA topoisomerase 3-alpha [Xenopus (Silurana) tropicalis].	25.38	457	270	16	27	452	277	693	3e-18	97.8
rs:WP_022005438	GTP-sensing transcriptional pleiotropic repressor CodY [Firmicutes bacterium CAG:194].	25.89	421	256	13	54	457	233	614	3e-18	97.4
tr:W7C9U0_BROTH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	23.88	448	273	16	29	452	44	447	3e-18	97.1
rs:WP_018882556	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	29.18	329	180	8	36	350	233	522	3e-18	97.8
rs:WP_034123499	DNA topoisomerase I, partial [Peptococcaceae bacterium BICA1-7].	24.45	454	261	13	54	455	234	657	3e-18	97.4
tr:Q3TPE4_MOUSE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.03	438	257	15	40	450	289	686	3e-18	97.4
tr:B8CN12_SHEPW	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.25	419	251	13	42	446	273	647	3e-18	97.8
rs:WP_033197948	hypothetical protein, partial [Gemmata obscuriglobus].	25.73	447	256	13	36	454	12	410	3e-18	97.4
rs:WP_024720597	DNA topoisomerase I [Clostridiales bacterium VE202-01].	26.27	415	237	13	61	455	239	604	3e-18	97.4
rs:WP_015457551	DNA topoisomerase I subunit omega [Sphingomonas sp. MM-1].	26.73	505	259	19	1	452	171	617	3e-18	97.8
rs:WP_013292006	DNA topoisomerase I [Gallionella capsiferriformans].	26.92	390	230	13	77	450	263	613	3e-18	97.8
rs:WP_029488353	DNA topoisomerase I [Epulopiscium sp. 'N.t. morphotype B'].	25.68	405	244	12	65	454	243	605	3e-18	97.4
rs:WP_029342082	MULTISPECIES: DNA topoisomerase I [Exiguobacterium].	25.90	417	246	16	60	454	236	611	3e-18	97.4
tr:S7PHJ6_MYOBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.00	427	244	14	60	456	285	669	3e-18	97.8
rs:WP_041774651	DNA topoisomerase [Leptospirillum ferrooxidans].	25.73	412	250	15	61	452	252	627	3e-18	97.8
rs:WP_018499586	DNA topoisomerase I [Leptotrichia wadei].	25.39	386	225	12	18	379	186	532	3e-18	97.8
rs:WP_032820919	topoisomerase I, partial [Oenococcus oeni].	31.96	194	105	6	57	237	1	180	3e-18	92.8
rs:WP_024684404	DNA topoisomerase I [Pseudomonas syringae].	28.33	413	239	18	47	446	259	627	3e-18	97.8
sp:TOP1_ZYMMO	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	26.09	437	262	14	41	452	222	622	3e-18	97.8
rs:WP_034077591	MULTISPECIES: DNA topoisomerase I [Gammaproteobacteria].	26.03	438	257	17	36	459	213	597	3e-18	97.4
rs:XP_009188109	PREDICTED: DNA topoisomerase 3-alpha [Papio anubis].	26.16	409	244	13	60	450	310	678	3e-18	97.8
tr:J5U251_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.04	441	245	16	68	455	214	617	3e-18	97.4
rs:WP_029187270	DNA topoisomerase I [Streptococcus suis].	23.29	438	271	12	34	452	222	613	3e-18	97.4
rs:WP_024352735	DNA topoisomerase I [Brevundimonas naejangsanensis].	26.59	425	250	15	60	454	242	634	3e-18	97.8
rs:WP_035229648	DNA topoisomerase I [Alcanivorax sp. 19-m-6].	25.56	399	247	12	60	446	279	639	3e-18	97.8
rs:WP_027088939	DNA topoisomerase I [[Clostridium] saccharogumia].	26.27	415	237	13	61	455	239	604	3e-18	97.4
rs:WP_008437341	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	25.47	428	273	15	46	459	230	625	3e-18	97.4
rs:WP_032836200	DNA topoisomerase I [Fusobacterium sp. OBRC1].	27.17	368	213	12	26	377	212	540	3e-18	97.4
rs:XP_008937408	PREDICTED: DNA topoisomerase 3-alpha, partial [Merops nubicus].	25.84	445	265	16	39	456	262	668	3e-18	97.8
rs:WP_017768572	DNA topoisomerase III [Streptococcus agalactiae].	27.46	346	213	10	60	399	264	577	3e-18	97.4
rs:WP_020621258	DNA topoisomerase I [Cohnella laeviribosi].	24.95	469	282	17	18	457	187	614	3e-18	97.4
rs:WP_028040262	DNA topoisomerase I [Caulobacter sp. URHA0033].	27.06	436	243	15	52	452	234	629	3e-18	97.8
rs:WP_007162385	topoisomerase I [Pseudomonas psychrotolerans].	27.27	396	227	13	68	446	274	625	3e-18	97.8
rs:WP_009106404	DNA topoisomerase I [Desulfovibrio sp. U5L].	25.48	416	250	12	54	452	232	604	3e-18	97.4
tr:D1Y390_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.89	458	268	14	26	454	277	687	3e-18	97.4
rs:WP_035266776	DNA topoisomerase I [Acinetobacter sp. Ver3].	27.25	356	212	12	40	384	267	586	3e-18	97.8
tr:A0A093FX84_PICPB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.90	444	264	16	40	456	271	676	3e-18	97.8
rs:WP_023944170	DNA topoisomerase I [Streptococcus mitis].	24.45	409	236	14	66	452	254	611	3e-18	97.4
rs:WP_044773639	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	3e-18	97.4
rs:WP_047030324	DNA topoisomerase I [Hoeflea sp. IMCC20628].	27.21	419	244	14	67	452	248	638	3e-18	97.8
rs:WP_028877907	DNA topoisomerase I [Terasakiella pusilla].	26.71	483	285	15	7	457	194	639	3e-18	97.8
tr:K8CP04_CROSK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	45.98	87	47	0	36	122	215	301	3e-18	94.7
rs:XP_011878275	PREDICTED: DNA topoisomerase 3 isoform X2 [Vollenhovia emeryi].	25.78	450	265	15	30	449	285	695	3e-18	97.8
tr:I0IL87_LEPFC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.73	412	250	15	61	452	286	661	3e-18	97.8
rs:WP_004609725	DNA topoisomerase I [[Clostridium] spiroforme].	24.82	415	243	12	61	455	239	604	3e-18	97.4
tr:F9PVG5_9STRE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	24.76	412	243	13	60	452	108	471	4e-18	97.1
rs:XP_005370069	PREDICTED: DNA topoisomerase 3-beta-1 [Microtus ochrogaster].	23.85	457	267	17	25	453	247	650	4e-18	97.8
rs:WP_035184592	DNA topoisomerase I [Lactobacillus delbrueckii].	26.79	433	245	17	43	452	251	634	4e-18	97.4
rs:WP_044988648	DNA topoisomerase III, partial [Tyzzerella nexilis].	29.23	260	148	10	47	283	249	495	4e-18	97.1
rs:WP_023512787	DNA topoisomerase 1 [Shinella sp. DD12].	26.35	444	254	16	47	452	230	638	4e-18	97.8
rs:XP_007080858	PREDICTED: DNA topoisomerase 3-alpha [Panthera tigris altaica].	25.94	424	246	14	60	455	310	693	4e-18	97.8
rs:XP_006103914	PREDICTED: DNA topoisomerase 3-alpha [Myotis lucifugus].	26.00	427	244	14	60	456	310	694	4e-18	97.8
rs:XP_004400575	PREDICTED: DNA topoisomerase 3-beta-1 [Odobenus rosmarus divergens].	24.04	441	255	16	40	453	263	650	4e-18	97.4
rs:XP_007647350	PREDICTED: DNA topoisomerase 3-alpha isoform X4 [Cricetulus griseus].	25.39	445	263	15	40	455	212	616	4e-18	97.8
tr:G1NSV2_MYOLU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.00	427	244	14	60	456	310	694	4e-18	97.8
rs:WP_005962844	DNA topoisomerase I [Fusobacterium necrophorum].	27.20	375	210	12	22	378	204	533	4e-18	97.4
rs:WP_042124336	DNA topoisomerase I [Pseudomonas japonica].	26.46	393	234	12	68	446	275	626	4e-18	97.4
rs:WP_029760461	DNA topoisomerase I [Geobacillus thermodenitrificans].	24.89	450	266	16	34	457	210	613	4e-18	97.4
rs:WP_040550400	DNA topoisomerase I [Pyramidobacter piscolens].	24.89	458	268	14	26	454	219	629	4e-18	97.4
rs:WP_045759471	DNA topoisomerase I [Streptococcus parasanguinis].	23.46	422	258	12	49	452	235	609	4e-18	97.4
rs:XP_008695765	PREDICTED: DNA topoisomerase 3-beta-1 [Ursus maritimus].	23.81	441	256	16	40	453	263	650	4e-18	97.4
rs:XP_011878274	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Vollenhovia emeryi].	25.78	450	265	15	30	449	285	695	4e-18	97.8
rs:WP_008427267	DNA topoisomerase I [Natronococcus jeotgali].	23.89	427	274	14	40	454	263	650	4e-18	97.4
rs:WP_037487916	DNA topoisomerase I [Snodgrassella alvi].	25.06	431	247	13	50	452	234	616	4e-18	97.4
rs:WP_032888841	DNA topoisomerase I [Fusobacterium nucleatum].	27.17	368	213	12	26	377	212	540	4e-18	97.4
rs:WP_017671279	DNA topoisomerase I [Blastomonas sp. AAP53].	27.78	414	241	15	60	452	241	617	4e-18	97.4
rs:WP_009765522	DNA topoisomerase I [Sporosarcina newyorkensis].	24.42	434	265	16	40	452	217	608	4e-18	97.4
rs:WP_035845126	DNA topoisomerase I [Defluviimonas sp. 20V17].	25.81	434	265	13	44	454	226	625	4e-18	97.4
rs:WP_034840251	DNA topoisomerase I [[Clostridium] cellulosi].	24.48	429	260	14	47	454	226	611	4e-18	97.4
rs:WP_025005757	DNA topoisomerase I [Lactobacillus gallinarum].	25.62	406	243	13	69	457	259	622	4e-18	97.4
rs:XP_005870224	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Myotis brandtii].	26.00	427	244	14	60	456	310	694	4e-18	97.8
tr:A0A078QP62_BACVU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.74	384	251	12	21	394	123	478	4e-18	96.7
rs:WP_027408673	DNA topoisomerase I [Anoxybacillus tepidamans].	26.33	433	250	18	49	457	226	613	4e-18	97.4
rs:WP_016252326	DNA topoisomerase 1 [Enterococcus cecorum].	24.61	447	271	19	34	457	211	614	4e-18	97.4
rs:WP_044959040	DNA topoisomerase I [Shuttleworthia sp. MSX8B].	24.47	425	264	10	50	457	230	614	4e-18	97.4
rs:WP_003245261	topoisomerase I [Pseudomonas mendocina].	25.74	408	256	13	47	446	257	625	4e-18	97.4
rs:WP_037048654	MULTISPECIES: DNA topoisomerase I [Pseudomonas aeruginosa group].	26.33	395	232	14	68	446	274	625	4e-18	97.4
rs:WP_013008503	DNA topoisomerase I [Deferribacter desulfuricans].	24.47	421	260	12	47	450	224	603	4e-18	97.4
rs:XP_008270403	PREDICTED: DNA topoisomerase 3-beta-1 [Oryctolagus cuniculus].	24.26	441	254	16	40	453	264	651	4e-18	97.4
rs:WP_004278474	topoisomerase I [Acinetobacter lwoffii].	27.73	321	192	10	40	356	268	552	4e-18	97.4
rs:XP_005523120	PREDICTED: DNA topoisomerase 3-alpha [Pseudopodoces humilis].	25.95	447	262	16	39	456	276	682	4e-18	97.8
rs:WP_020044548	DNA topoisomerase I [alpha proteobacterium SCGC AAA298-K06].	26.05	430	263	14	47	454	231	627	4e-18	97.4
rs:WP_024746280	DNA topoisomerase I [Lactobacillus namurensis].	26.17	447	260	17	34	457	226	625	4e-18	97.4
rs:WP_006655377	DNA topoisomerase I [Helicobacter canadensis].	25.47	428	255	15	41	450	218	599	4e-18	97.4
rs:WP_021155407	MULTISPECIES: DNA topoisomerase I [Proteobacteria].	26.03	438	257	17	36	459	213	597	4e-18	97.4
rs:WP_034649196	DNA topoisomerase I [Bacillus megaterium].	24.18	488	295	21	1	457	170	613	4e-18	97.4
rs:WP_004976132	DNA topoisomerase I [Acinetobacter towneri].	27.41	321	193	10	40	356	267	551	4e-18	97.4
rs:XP_005261870	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Homo sapiens].	24.51	457	264	17	25	453	111	514	4e-18	97.4
rs:WP_048108634	DNA topoisomerase [Methanosarcina barkeri].	25.94	451	266	19	30	454	238	646	4e-18	97.4
rs:WP_026827998	DNA topoisomerase I [Exiguobacterium sibiricum].	24.42	475	266	16	34	450	210	649	4e-18	97.4
rs:WP_019836908	topoisomerase I [Acinetobacter sp. MDS7A].	27.41	321	193	10	40	356	267	551	4e-18	97.4
rs:WP_032946566	DNA topoisomerase I, partial [Bacteroides vulgatus].	24.74	384	251	12	21	394	139	494	4e-18	96.7
rs:XP_009436166	PREDICTED: DNA topoisomerase 3-beta-1 isoform X4 [Pan troglodytes].	24.51	457	264	17	25	453	111	514	4e-18	97.4
rs:WP_042396551	DNA topoisomerase I [Clostridium sp. JCC].	25.43	460	247	17	47	449	224	644	4e-18	97.4
rs:WP_038414203	DNA topoisomerase I [Pseudomonas cremoricolorata].	26.09	391	238	12	68	446	275	626	4e-18	97.4
rs:WP_008111438	topoisomerase I [Pseudoalteromonas sp. BSi20311].	25.96	416	256	14	42	446	257	631	4e-18	97.4
rs:WP_006109876	DNA topoisomerase I [Natrialba asiatica].	24.01	404	260	12	60	454	267	632	4e-18	97.4
rs:WP_012995298	DNA topoisomerase I [Thermoanaerobacter italicus].	25.31	490	283	19	1	454	170	612	4e-18	97.4
tr:B0QZI1_MOUSE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.03	438	257	15	40	450	264	661	4e-18	97.4
rs:WP_039883922	DNA topoisomerase I [Mogibacterium sp. CM50].	24.04	441	245	16	68	455	237	640	4e-18	97.4
rs:WP_047567674	DNA topoisomerase I, partial [Mesorhizobium sp. F7].	26.13	444	252	17	47	452	230	635	4e-18	97.4
rs:WP_032009232	DNA topoisomerase I [Acinetobacter baumannii].	27.23	426	255	18	40	452	266	649	4e-18	97.4
tr:A0A0E0IGT0_ORYNI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.11	438	268	14	39	451	322	724	4e-18	97.4
tr:E6QED7_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CBI05563.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI05563.1};	29.06	413	218	19	70	454	136	501	4e-18	97.4
rs:WP_036806692	DNA topoisomerase I [Planomicrobium glaciei].	25.51	439	261	16	36	452	213	607	4e-18	97.4
rs:WP_042086403	DNA topoisomerase I [alpha proteobacterium Q-1].	26.23	446	258	16	41	452	224	632	4e-18	97.4
tr:I3JP28_ORENI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.15	472	272	14	24	456	271	695	4e-18	97.4
rs:WP_025015133	DNA topoisomerase I [Lactobacillus kitasatonis].	25.37	406	244	13	69	457	259	622	4e-18	97.4
rs:WP_030069262	DNA topoisomerase I [Halomonas alkaliantarctica].	27.66	394	219	17	77	452	296	641	4e-18	97.4
rs:XP_004670830	PREDICTED: DNA topoisomerase 3-beta-1 [Jaculus jaculus].	24.26	441	254	16	40	453	263	650	4e-18	97.4
tr:W4YMN5_STRPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:SPU_017059-tr};	22.74	431	272	13	40	453	127	513	4e-18	97.4
rs:WP_033117512	DNA topoisomerase I [Intestinimonas butyriciproducens].	26.06	426	254	13	50	454	230	615	4e-18	97.4
rs:XP_008958125	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Pan paniscus].	24.51	457	264	17	25	453	129	532	4e-18	97.4
rs:WP_039578790	DNA topoisomerase I [Pseudomonas parafulva].	26.72	408	252	13	47	446	258	626	4e-18	97.4
rs:WP_018295093	DNA topoisomerase I [Mariprofundus ferrooxydans].	25.00	408	251	13	62	454	250	617	4e-18	97.4
rs:XP_003496375	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Cricetulus griseus].	25.71	424	247	14	60	455	310	693	4e-18	97.4
rs:WP_033368960	DNA topoisomerase I [Selenomonas bovis].	27.21	441	250	17	41	456	264	658	4e-18	97.4
rs:WP_037519864	DNA topoisomerase I [Sphingobium yanoikuyae].	27.23	437	256	17	40	452	219	617	4e-18	97.4
rs:WP_045085262	DNA topoisomerase I [[Clostridium] cellulosi].	24.48	429	260	14	47	454	226	611	4e-18	97.1
rs:WP_021795786	hypothetical protein [Thermoplasmatales archaeon A-plasma].	22.76	514	256	15	37	454	249	717	4e-18	97.4
rs:WP_016390852	MULTISPECIES: DNA topoisomerase I [Cycloclasticus].	26.52	396	234	15	77	452	263	621	4e-18	97.4
rs:WP_012816917	DNA topoisomerase I [Zymomonas mobilis].	26.09	437	262	14	41	452	222	622	4e-18	97.8
tr:A0A0E0B042_9ORYZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.11	438	268	14	39	451	209	611	4e-18	97.4
rs:WP_002836341	DNA topoisomerase I [Finegoldia magna].	23.28	481	294	15	1	452	171	605	4e-18	97.1
sp:TOP3B_HUMAN	RecName: Full=DNA topoisomerase 3-beta-1; EC=5.99.1.2; AltName: Full=DNA topoisomerase III beta-1;	24.51	457	264	17	25	453	247	650	4e-18	97.4
rs:WP_028410804	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.18	488	295	21	1	457	170	613	4e-18	97.1
rs:WP_011887130	DNA topoisomerase I [Geobacillus thermodenitrificans].	24.89	450	266	16	34	457	210	613	4e-18	97.1
tr:S4RC13_PETMA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.11	429	228	15	65	456	317	693	4e-18	97.4
rs:WP_044313220	DNA topoisomerase I [Pseudomonas syringae].	28.10	395	223	17	69	446	277	627	4e-18	97.4
rs:WP_010920309	DNA topoisomerase I [Caulobacter vibrioides].	26.73	434	247	16	52	452	234	629	4e-18	97.4
rs:XP_004742578	PREDICTED: DNA topoisomerase 3-beta-1 isoform X5 [Mustela putorius furo].	23.81	441	256	16	40	453	250	637	4e-18	97.4
rs:WP_048004063	DNA topoisomerase I [Bacillus marisflavi].	23.67	431	263	15	50	457	227	614	4e-18	97.1
rs:XP_009436164	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Pan troglodytes].	24.51	457	264	17	25	453	129	532	4e-18	97.4
tr:F3FHN5_PSESX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	28.47	411	237	18	49	446	27	393	4e-18	97.1
rs:WP_013439705	DNA topoisomerase I [Lactobacillus delbrueckii].	26.79	433	245	17	43	452	251	634	4e-18	97.1
rs:WP_005360176	DNA topoisomerase I [Eubacterium ventriosum].	24.94	441	273	11	36	457	211	612	4e-18	97.1
rs:XP_005468447	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Oreochromis niloticus].	24.15	472	272	14	24	456	289	713	4e-18	97.4
rs:WP_045254282	DNA topoisomerase I [Microbacterium foliorum].	31.38	325	175	14	42	356	259	545	4e-18	97.4
rs:WP_027113602	DNA topoisomerase I [Lachnospiraceae bacterium NK4A144].	27.07	399	234	14	74	454	257	616	4e-18	97.1
rs:WP_029087405	DNA topoisomerase I [Brevundimonas aveniformis].	28.44	436	250	14	47	454	227	628	4e-18	97.4
rs:WP_048365159	DNA topoisomerase I [Pseudomonas sp. DSM 29166].	27.85	395	224	17	69	446	277	627	4e-18	97.4
rs:XP_007647342	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Cricetulus griseus].	25.71	424	247	14	60	455	309	692	4e-18	97.4
rs:WP_037506680	DNA topoisomerase I [Sphingobium yanoikuyae].	27.23	437	256	17	40	452	219	617	4e-18	97.4
rs:WP_041140988	DNA topoisomerase I [Sulfurovum sp. PC08-66].	26.23	427	258	14	41	452	220	604	4e-18	97.1
tr:X8HMV1_9FUSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.17	368	213	12	26	377	209	537	4e-18	97.1
rs:WP_006352524	DNA topoisomerase I [Lactobacillus amylolyticus].	25.68	405	242	13	70	457	260	622	4e-18	97.1
rs:WP_004323216	DNA topoisomerase III [Bacteroides ovatus].	24.24	330	219	8	61	385	263	566	4e-18	97.1
rs:XP_003807785	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Pan paniscus].	24.51	457	264	17	25	453	247	650	4e-18	97.4
rs:WP_033799342	DNA topoisomerase I, partial [Bacillus pseudomycoides].	27.41	270	173	7	192	454	1	254	4e-18	95.1
rs:WP_020857205	DNA topoisomerase I [SAR86 cluster bacterium SAR86A].	25.58	391	232	14	77	452	286	632	4e-18	97.4
rs:XP_515006	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Pan troglodytes].	24.51	457	264	17	25	453	247	650	4e-18	97.4
rs:XP_004742575	PREDICTED: DNA topoisomerase 3-beta-1 [Mustela putorius furo].	23.81	441	256	16	40	453	263	650	4e-18	97.4
tr:F6SDD7_MOUSE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.85	457	267	17	25	453	42	445	4e-18	96.7
rs:XP_005468449	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Oreochromis niloticus].	24.15	472	272	14	24	456	209	633	4e-18	97.4
rs:WP_046324810	DNA topoisomerase I [Lactobacillus melliventris].	25.62	402	238	13	69	452	255	613	4e-18	97.1
rs:XP_007130667	PREDICTED: DNA topoisomerase 3-beta-1 [Physeter catodon].	24.04	441	255	16	40	453	263	650	5e-18	97.4
rs:WP_024381859	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	5e-18	97.1
rs:WP_003011242	DNA topoisomerase I [Streptococcus parasanguinis].	23.46	422	258	12	49	452	237	611	5e-18	97.1
rs:WP_009096324	topoisomerase I [Halomonas sp. GFAJ-1].	27.48	393	221	16	77	452	296	641	5e-18	97.4
rs:WP_008415922	DNA topoisomerase I [Halalkalicoccus jeotgali].	24.40	377	241	10	86	454	292	632	5e-18	97.4
rs:WP_009404616	DNA topoisomerase I subunit omega [Pseudomonas putida].	26.01	396	232	12	68	446	275	626	5e-18	97.4
rs:WP_043334996	DNA topoisomerase I [Belnapia moabensis].	26.15	455	264	15	41	454	225	648	5e-18	97.4
rs:WP_005261741	DNA topoisomerase I [Acinetobacter sp. CIP 101966].	27.73	321	192	10	40	356	268	552	5e-18	97.4
rs:WP_038671950	DNA topoisomerase I [Ruminococcus bicirculans].	24.23	421	270	13	47	452	225	611	5e-18	97.1
rs:WP_005400852	topoisomerase I [Acinetobacter johnsonii].	26.93	427	255	19	40	452	268	651	5e-18	97.4
rs:WP_000445593	DNA topoisomerase I [Streptococcus pneumoniae].	24.45	409	236	14	66	452	236	593	5e-18	97.1
rs:WP_027598369	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	27.27	396	227	13	68	446	274	625	5e-18	97.4
rs:WP_014414404	DNA topoisomerase I [Rhodospirillum photometricum].	26.87	428	251	14	60	454	243	641	5e-18	97.4
tr:A0A091IBC6_CALAN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.56	446	265	17	39	456	270	676	5e-18	97.4
rs:WP_018282125	hypothetical protein [zeta proteobacterium SCGC AB-137-C09].	25.88	483	249	17	47	459	230	673	5e-18	97.1
rs:WP_024409355	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	5e-18	97.1
rs:WP_011417280	DNA topoisomerase I [Syntrophus aciditrophicus].	27.23	404	221	16	77	452	274	632	5e-18	97.1
rs:WP_007719372	DNA topoisomerase I [Brevibacillus sp. BC25].	24.48	433	260	14	49	458	226	614	5e-18	97.1
rs:WP_047341422	DNA topoisomerase I [Enterococcus cecorum].	24.61	447	271	19	34	457	211	614	5e-18	97.1
rs:WP_038058400	DNA topoisomerase I [Thermus sp. YIM 77409].	26.54	456	244	18	36	454	244	645	5e-18	97.4
rs:WP_019625965	DNA topoisomerase I [Thioalkalivibrio sp. ALJT].	28.99	345	195	9	61	384	259	574	5e-18	97.4
rs:WP_029180300	DNA topoisomerase I [Streptococcus suis].	23.52	421	258	11	50	452	239	613	5e-18	97.1
rs:WP_015652572	hypothetical protein [uncultured Sulfuricurvum sp. RIFRC-1].	25.18	421	251	15	50	452	226	600	5e-18	97.1
rs:WP_013617089	DNA topoisomerase III [Bacteroides salanitronis].	25.30	336	220	6	61	394	265	571	5e-18	97.1
rs:WP_044396592	DNA topoisomerase I [Bacillus subterraneus].	23.19	483	296	18	1	452	170	608	5e-18	97.1
tr:A0KVZ3_SHESA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.22	450	269	17	10	446	248	647	5e-18	97.4
tr:A0A090EG08_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.01	448	255	19	41	452	224	635	5e-18	97.1
rs:WP_035145808	DNA topoisomerase I [Lactobacillus sakei].	26.38	436	261	15	43	458	222	617	5e-18	97.1
rs:WP_017925209	DNA topoisomerase I [Thioalkalivibrio sp. HL-Eb18].	28.41	359	201	9	36	377	233	552	5e-18	97.1
tr:U7TQJ4_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.17	368	213	12	26	377	209	537	5e-18	97.1
rs:WP_044653275	DNA topoisomerase I [Bacteroides acidifaciens].	24.24	330	219	8	61	385	263	566	5e-18	96.7
rs:WP_020403880	hypothetical protein [Gracilimonas tropica].	27.23	393	213	10	41	398	251	605	5e-18	97.1
rs:WP_047795418	DNA topoisomerase I [Exiguobacterium sp. JLM-2].	25.43	409	249	12	66	454	242	614	5e-18	97.1
rs:XP_007617064	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Cricetulus griseus].	25.39	445	263	15	40	455	288	692	5e-18	97.4
rs:WP_044771230	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	5e-18	97.1
rs:WP_013730365	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	5e-18	97.1
rs:WP_024390904	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	5e-18	97.1
rs:WP_014636962	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	5e-18	97.1
rs:WP_015881378	DNA topoisomerase I [Exiguobacterium sp. AT1b].	25.43	409	249	12	66	454	242	614	5e-18	97.1
tr:C5ZW76_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.41	425	259	14	41	450	220	601	5e-18	97.1
rs:WP_003001546	DNA topoisomerase I [Streptococcus parasanguinis].	23.46	422	258	12	49	452	235	609	5e-18	97.1
tr:U6D9Q2_NEOVI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.81	441	256	16	40	453	263	650	5e-18	97.1
rs:WP_031421645	DNA topoisomerase I [Exiguobacterium sp. NG55].	25.43	409	249	12	66	454	242	614	5e-18	97.1
rs:XP_011683116	PREDICTED: DNA topoisomerase 3-beta-1 [Strongylocentrotus purpuratus].	22.74	431	272	13	40	453	166	552	5e-18	97.1
rs:WP_006145648	DNA topoisomerase I [Streptococcus peroris].	25.12	406	237	13	66	452	254	611	5e-18	97.1
rs:WP_002936490	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	5e-18	97.1
tr:D2I7M2_AILME	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.81	441	256	16	40	453	240	627	5e-18	97.1
rs:WP_006317433	DNA topoisomerase I [Caldisalinibacter kiritimatiensis].	25.76	462	243	18	47	450	228	647	5e-18	97.1
tr:X7RZ04_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.17	368	213	12	26	377	209	537	5e-18	97.1
rs:WP_014947339	DNA topoisomerase I [Streptococcus pneumoniae].	24.45	409	236	14	66	452	254	611	5e-18	97.1
rs:WP_041136416	DNA topoisomerase I [Sulfurovum sp. AS07-7].	24.77	432	251	16	46	454	223	603	5e-18	97.1
rs:WP_012545297	DNA topoisomerase I [Thermodesulfovibrio yellowstonii].	25.93	432	258	13	41	452	233	622	5e-18	97.1
rs:XP_007617066	PREDICTED: DNA topoisomerase 3-alpha isoform X4 [Cricetulus griseus].	25.39	445	263	15	40	455	212	616	5e-18	97.1
rs:XP_010001864	PREDICTED: DNA topoisomerase 3-alpha [Chaetura pelagica].	25.84	445	263	17	40	456	291	696	5e-18	97.4
rs:XP_008573018	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Galeopterus variegatus].	24.04	441	255	16	40	453	263	650	5e-18	97.1
rs:WP_023445655	topoisomerase I [Pseudomonas chloritidismutans].	24.88	422	267	12	42	452	253	635	5e-18	97.1
rs:WP_005587787	DNA topoisomerase I [Clostridium ultunense].	22.66	534	290	18	1	449	153	648	5e-18	97.1
tr:J6B175_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJX75617.1}; Flags: Fragment;	35.22	159	94	3	207	365	2	151	5e-18	91.3
rs:WP_005022546	DNA topoisomerase I [Helicobacter pullorum].	25.52	431	251	13	41	450	218	599	5e-18	97.1
rs:WP_000474619	hypothetical protein, partial [Streptococcus agalactiae].	26.29	350	218	9	57	398	58	375	5e-18	95.1
rs:WP_002362367	DNA topoisomerase, partial [Enterococcus faecium].	29.91	234	148	6	57	285	135	357	5e-18	94.7
rs:WP_040520241	DNA topoisomerase I, partial [Glaciecola punicea].	27.75	400	229	18	71	452	288	645	5e-18	97.1
rs:WP_044776982	DNA topoisomerase I [Streptococcus suis].	23.28	421	259	11	50	452	239	613	5e-18	97.1
rs:XP_011216356	PREDICTED: DNA topoisomerase 3-beta-1 [Ailuropoda melanoleuca].	23.81	441	256	16	40	453	263	650	5e-18	97.1
rs:WP_020814402	DNA topoisomerase I [[Clostridium] papyrosolvens].	24.30	465	284	14	22	454	191	619	5e-18	97.1
rs:WP_040995667	DNA topoisomerase I, partial [Mesorhizobium sp. SOD10].	27.01	448	255	19	41	452	224	635	5e-18	97.1
rs:WP_000445598	DNA topoisomerase I [Streptococcus pneumoniae].	24.45	409	236	14	66	452	236	593	5e-18	97.1
rs:XP_008573019	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Galeopterus variegatus].	24.04	441	255	16	40	453	219	606	5e-18	97.1
rs:WP_041963169	DNA topoisomerase I [Sulfurospirillum cavolei].	27.07	399	219	15	76	452	257	605	5e-18	97.1
rs:WP_032891759	DNA topoisomerase I [Fusobacterium nucleatum].	27.17	368	213	12	26	377	212	540	5e-18	97.1
tr:G9KUN5_MUSPF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.81	441	256	16	40	453	263	650	5e-18	97.1
rs:WP_001681279	DNA topoisomerase III, partial [Salmonella enterica].	42.34	111	64	0	275	385	3	113	5e-18	91.7
rs:WP_011390950	DNA topoisomerase I [Rhodospirillum rubrum].	26.61	466	268	18	28	454	212	642	5e-18	97.1
tr:S9YRU2_9CETA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.77	446	268	15	16	434	302	702	5e-18	97.4
tr:A0A060H6T2_XYLFS	SubName: Full=Topoisomerase I {ECO:0000313|EMBL:AIC11298.1};	57.75	71	30	0	236	306	1	71	5e-18	90.1
rs:WP_038663823	DNA topoisomerase I [Sphingomonas taxi].	28.63	454	257	17	24	452	206	617	5e-18	97.1
rs:WP_005958225	DNA topoisomerase I [Fusobacterium necrophorum].	27.86	359	206	11	38	378	210	533	5e-18	97.1
rs:WP_044686750	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	5e-18	97.1
rs:XP_005612443	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Equus caballus].	23.63	457	268	17	25	453	247	650	5e-18	97.1
rs:WP_041412994	DNA topoisomerase I [Shewanella sp. ANA-3].	26.22	450	269	17	10	446	232	631	5e-18	97.1
rs:WP_044023756	DNA topoisomerase I, partial [Bacillus cereus].	24.69	405	246	13	1	379	170	541	5e-18	96.7
rs:XP_007617063	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Cricetulus griseus].	25.39	445	263	15	40	455	289	693	5e-18	97.1
rs:XP_007617065	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Cricetulus griseus].	25.39	445	263	15	40	455	264	668	6e-18	97.1
rs:WP_024325912	DNA topoisomerase I [Thioalkalivibrio sp. AKL19].	28.41	359	201	9	36	377	233	552	6e-18	97.1
rs:WP_012211826	DNA topoisomerase I [Lactobacillus helveticus].	24.71	429	265	12	45	457	236	622	6e-18	96.7
rs:XP_008497098	PREDICTED: DNA topoisomerase 3-alpha [Calypte anna].	25.56	446	265	17	39	456	290	696	6e-18	97.1
rs:WP_012775596	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	6e-18	96.7
tr:F8K840_STRPY	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.12	259	166	7	143	398	355	601	6e-18	96.7
rs:XP_006877695	PREDICTED: DNA topoisomerase 3-beta-1 [Chrysochloris asiatica].	24.04	441	255	16	40	453	263	650	6e-18	97.1
rs:WP_032946806	MULTISPECIES: DNA topoisomerase I [Bacteroides].	23.70	384	257	10	21	395	220	576	6e-18	96.7
rs:WP_013257954	DNA topoisomerase I [Desulfarculus baarsii].	25.35	426	270	12	47	452	225	622	6e-18	97.1
rs:WP_031434896	DNA topoisomerase I [Methylomarinum vadi].	27.25	433	245	19	46	452	234	622	6e-18	97.1
rs:XP_008507640	PREDICTED: DNA topoisomerase 3-beta-1 [Equus przewalskii].	23.63	457	268	17	25	453	232	635	6e-18	97.1
rs:WP_032821588	topoisomerase I, partial [Oenococcus oeni].	32.57	218	124	8	33	237	7	214	6e-18	92.4
rs:WP_018368536	DNA topoisomerase I [Streptococcus entericus].	22.88	459	277	13	19	452	206	612	6e-18	96.7
rs:WP_014713336	MULTISPECIES: DNA topoisomerase I [Streptococcus].	23.46	422	258	12	49	452	237	611	6e-18	96.7
rs:XP_004442433	PREDICTED: DNA topoisomerase 3-beta-1 [Ceratotherium simum simum].	23.85	457	267	17	25	453	247	650	6e-18	97.1
rs:WP_044498954	DNA topoisomerase I [Pseudomonas sp. 12M76_air].	24.83	435	270	13	35	459	218	605	6e-18	96.7
rs:WP_038452705	DNA topoisomerase I [Campylobacter iguaniorum].	25.30	423	250	13	47	450	224	599	6e-18	96.7
tr:J1JMX7_STREE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.45	409	236	14	66	452	207	564	6e-18	96.7
rs:WP_029997262	DNA topoisomerase [Streptococcus suis].	27.58	330	205	10	60	385	264	563	6e-18	96.7
tr:A0A0D6PF16_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.01	422	248	15	60	452	252	642	6e-18	97.1
rs:WP_011072651	topoisomerase I [Shewanella oneidensis].	26.76	426	254	18	35	446	250	631	6e-18	97.1
rs:WP_013150348	DNA topoisomerase I [Thermoanaerobacter mathranii].	25.56	493	278	21	1	454	170	612	6e-18	96.7
rs:WP_011570557	DNA topoisomerase I [Haloquadratum walsbyi].	22.64	402	267	12	61	454	283	648	6e-18	97.1
rs:WP_045811600	DNA topoisomerase I [Brevundimonas sp. KM4].	27.23	426	248	15	60	454	242	636	6e-18	97.1
rs:WP_048398761	DNA topoisomerase I [Pseudomonas sp. DSM 28140].	27.85	395	224	17	69	446	277	627	6e-18	97.1
rs:WP_044683261	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	6e-18	96.7
tr:G0UHE0_9LACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.69	432	248	16	45	452	255	637	6e-18	96.7
rs:WP_003436352	DNA topoisomerase I subunit omega [Pseudomonas syringae].	27.52	407	246	16	49	446	261	627	6e-18	97.1
rs:WP_044769733	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	6e-18	96.7
rs:WP_034161568	DNA topoisomerase I [Sphingomonas sp. ERG5].	28.78	403	229	15	71	452	252	617	6e-18	97.1
rs:WP_022226467	DNA topoisomerase [Clostridium sp. CAG:302].	25.71	389	236	10	75	450	249	597	6e-18	96.7
rs:WP_048033464	DNA topoisomerase I [Brevibacillus brevis].	24.77	432	258	14	49	457	226	613	6e-18	96.7
rs:WP_024055748	DNA topoisomerase, partial [Streptococcus parasanguinis].	23.46	422	258	12	49	452	111	485	6e-18	96.7
rs:WP_008403299	DNA topoisomerase I [Bacillus isronensis].	23.39	466	283	19	18	452	187	609	6e-18	96.7
rs:WP_000179655	DNA topoisomerase I [Streptococcus mitis].	24.45	409	236	14	66	452	254	611	6e-18	96.7
rs:WP_032948603	DNA topoisomerase I, partial [Bacteroides vulgatus].	35.68	185	112	5	60	243	263	441	6e-18	95.9
rs:WP_003417673	MULTISPECIES: topoisomerase I [Pseudomonas syringae group].	27.52	407	246	16	49	446	261	627	6e-18	97.1
rs:WP_033683782	DNA topoisomerase I [Streptococcus mitis].	24.45	409	236	14	66	452	254	611	6e-18	96.7
rs:WP_011815111	DNA topoisomerase I [Halorhodospira halophila].	28.57	350	192	11	61	384	267	584	6e-18	96.7
rs:WP_044628075	DNA topoisomerase I [Halomonas meridiana].	27.74	393	220	17	77	452	296	641	6e-18	97.1
rs:WP_015277422	DNA topoisomerase I [Pseudomonas stutzeri].	24.88	422	267	12	42	452	253	635	6e-18	97.1
rs:WP_000179635	DNA topoisomerase I [Streptococcus pneumoniae].	24.45	409	236	14	66	452	254	611	6e-18	96.7
rs:WP_048376916	DNA topoisomerase I [Pseudomonas lundensis].	27.40	416	247	16	42	446	256	627	6e-18	97.1
rs:WP_043888070	DNA topoisomerase I [Methylophaga thiooxydans].	27.74	429	247	19	46	452	234	621	6e-18	96.7
rs:WP_014555165	DNA topoisomerase I [Haloquadratum walsbyi].	22.89	402	266	12	61	454	283	648	6e-18	97.1
rs:WP_032048135	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	6e-18	97.1
rs:WP_013291693	DNA topoisomerase I [Clostridium cellulovorans].	23.60	428	264	12	47	454	230	614	6e-18	96.7
rs:WP_014820598	topoisomerase I [Pseudomonas stutzeri].	25.06	419	264	12	45	452	256	635	6e-18	97.1
rs:WP_025059920	DNA topoisomerase I [Sulfitobacter donghicola].	27.84	485	240	22	41	454	225	670	6e-18	97.1
rs:WP_014824496	DNA topoisomerase I [Solibacillus silvestris].	23.39	466	283	19	18	452	187	609	6e-18	96.7
rs:WP_000179645	DNA topoisomerase I [Streptococcus pneumoniae].	24.45	409	236	14	66	452	254	611	6e-18	96.7
rs:WP_021153232	DNA topoisomerase I [Streptococcus sp. HSISM1].	23.46	422	258	12	49	452	235	609	6e-18	96.7
rs:WP_009555384	DNA topoisomerase I [Oscillatoriales cyanobacterium JSC-12].	27.95	365	218	11	41	394	255	585	6e-18	97.1
rs:WP_021655081	DNA topoisomerase I [Clostridiales bacterium oral taxon 876].	25.99	431	244	16	50	454	229	610	6e-18	96.7
rs:WP_038593555	DNA topoisomerase I [Paenibacillus sp. FSL H7-0357].	26.78	422	242	16	62	457	234	614	6e-18	96.7
rs:XP_008154451	PREDICTED: DNA topoisomerase 3-alpha [Eptesicus fuscus].	26.51	430	238	15	60	456	310	694	6e-18	97.1
rs:WP_028256007	DNA topoisomerase I [Veillonella magna].	24.54	432	264	11	41	454	275	662	6e-18	96.7
rs:WP_003370501	topoisomerase I [Pseudomonas syringae].	27.52	407	246	16	49	446	261	627	7e-18	96.7
rs:WP_042751276	DNA topoisomerase I [Streptococcus mitis].	24.20	405	242	12	66	452	254	611	7e-18	96.7
rs:WP_011839553	DNA topoisomerase I [Staphylothermus marinus].	26.77	381	225	14	61	425	314	656	7e-18	96.7
rs:WP_022575798	topoisomerase I [Acinetobacter nosocomialis].	27.17	427	254	19	40	452	266	649	7e-18	96.7
rs:WP_017563077	DNA topoisomerase I [Nocardiopsis synnemataformans].	26.33	357	213	11	40	379	275	598	7e-18	97.1
rs:WP_018975043	DNA topoisomerase I [Saccharibacillus kuerlensis].	24.48	433	259	15	50	458	227	615	7e-18	96.7
rs:WP_028972477	hypothetical protein [Spirochaeta cellobiosiphila].	27.06	388	241	10	77	454	269	624	7e-18	96.7
rs:XP_010745514	PREDICTED: DNA topoisomerase 3-alpha [Larimichthys crocea].	24.63	471	269	14	24	455	277	700	7e-18	97.1
rs:WP_000179658	DNA topoisomerase I [Streptococcus mitis].	24.45	409	236	14	66	452	254	611	7e-18	96.7
rs:WP_043331932	DNA topoisomerase I [Cobetia marina].	28.04	403	231	17	70	458	291	648	7e-18	96.7
tr:C2D5U8_LACBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.35	185	120	3	56	237	10	190	7e-18	92.0
rs:WP_003412162	topoisomerase I [Pseudomonas syringae].	27.38	409	248	16	47	446	259	627	7e-18	96.7
gp:BC002432_1	topoisomerase (DNA) III beta [Homo sapiens]	24.51	457	264	17	25	453	247	650	7e-18	96.7
rs:WP_046269261	DNA topoisomerase I [Pseudomonas syringae].	27.52	407	246	16	49	446	261	627	7e-18	96.7
rs:WP_042900774	DNA topoisomerase I [Streptococcus mitis].	24.20	405	242	12	66	452	254	611	7e-18	96.7
rs:WP_024377726	DNA topoisomerase I [Streptococcus suis].	23.75	421	257	11	50	452	239	613	7e-18	96.7
rs:WP_013269241	DNA topoisomerase I [Brevundimonas subvibrioides].	27.69	437	261	15	43	452	225	633	7e-18	96.7
rs:WP_008457790	DNA topoisomerase I [Natrinema gari].	24.18	426	273	14	40	454	246	632	7e-18	96.7
rs:WP_036311140	DNA topoisomerase I [Methylophaga thiooxydans].	27.74	429	247	19	46	452	234	621	7e-18	96.7
rs:WP_003007403	DNA topoisomerase I [Streptococcus parasanguinis].	23.46	422	258	12	49	452	235	609	7e-18	96.7
rs:WP_043206689	DNA topoisomerase I [Pseudomonas putida].	26.52	396	230	12	68	446	275	626	7e-18	96.7
rs:XP_010618951	PREDICTED: DNA topoisomerase 3-beta-1 [Fukomys damarensis].	24.04	441	255	16	40	453	263	650	7e-18	96.7
rs:WP_035328942	DNA topoisomerase I [Bacillus firmus].	25.29	431	255	18	50	457	227	613	7e-18	96.7
rs:WP_023041398	DNA topoisomerase I [Fusobacterium nucleatum].	26.90	368	214	12	26	377	209	537	7e-18	96.7
tr:H1HCE5_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.96	366	220	10	26	377	209	537	7e-18	96.7
rs:WP_005902939	DNA topoisomerase I [Fusobacterium nucleatum].	26.90	368	214	12	26	377	212	540	7e-18	96.7
rs:WP_000179650	DNA topoisomerase I [Streptococcus pneumoniae].	24.45	409	236	14	66	452	254	611	7e-18	96.7
rs:WP_032027328	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	7e-18	96.7
rs:WP_047252202	DNA topoisomerase I [Corynebacterium testudinoris].	26.33	338	208	8	30	354	251	560	7e-18	96.7
rs:WP_041046419	DNA topoisomerase I [Wolbachia endosymbiont of Cimex lectularius].	24.83	439	258	14	47	452	231	630	7e-18	96.7
rs:XP_008061294	PREDICTED: DNA topoisomerase 3-beta-1 [Tarsius syrichta].	23.85	457	267	17	25	453	247	650	7e-18	96.7
rs:WP_018111526	DNA topoisomerase I [Thermus igniterrae].	26.38	417	226	15	61	454	245	603	7e-18	96.7
rs:WP_009660457	DNA topoisomerase I [Streptococcus sp. AS14].	23.62	436	258	13	40	452	227	610	7e-18	96.7
rs:WP_006801926	DNA topoisomerase I [Helicobacter winghamensis].	25.23	432	251	16	41	450	221	602	7e-18	96.7
rs:WP_039737107	DNA topoisomerase I [Hassallia byssoidea].	26.34	372	226	10	41	395	249	589	7e-18	96.7
rs:WP_000179659	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.45	409	236	14	66	452	254	611	7e-18	96.7
rs:WP_044450151	DNA topoisomerase I [Mastigocladus laminosus].	26.77	437	254	16	41	452	222	617	7e-18	96.7
rs:WP_002053435	MULTISPECIES: topoisomerase I [Acinetobacter calcoaceticus/baumannii complex].	27.17	427	254	19	40	452	266	649	7e-18	96.7
rs:WP_027606776	DNA topoisomerase I [Pseudomonas sp. LAMO17WK12:I2].	23.94	401	263	11	70	459	254	623	7e-18	96.3
rs:WP_001844626	DNA topoisomerase I [Streptococcus pneumoniae].	24.45	409	236	14	66	452	254	611	7e-18	96.7
rs:WP_017144898	DNA topoisomerase I [Fusobacterium nucleatum].	25.96	366	220	10	26	377	212	540	7e-18	96.7
rs:WP_000179661	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.45	409	236	14	66	452	254	611	7e-18	96.7
rs:WP_000179657	DNA topoisomerase I [Streptococcus mitis].	24.45	409	236	14	66	452	254	611	7e-18	96.7
rs:WP_000179656	DNA topoisomerase I [Streptococcus pseudopneumoniae].	24.45	409	236	14	66	452	254	611	7e-18	96.7
rs:WP_022423482	DNA topoisomerase [Clostridium sp. CAG:440].	31.75	189	119	4	47	226	272	459	7e-18	95.9
rs:WP_025063001	DNA topoisomerase I [Sulfitobacter guttiformis].	27.18	482	248	18	41	454	225	671	7e-18	96.7
rs:WP_000259051	DNA topoisomerase III [Streptococcus agalactiae].	28.70	338	200	11	71	399	272	577	7e-18	96.3
rs:WP_028693758	DNA topoisomerase I [Pseudomonas cremoricolorata].	25.83	391	239	12	68	446	275	626	7e-18	96.7
rs:WP_009650966	DNA topoisomerase I [Campylobacter sp. FOBRC14].	26.54	422	246	16	47	450	224	599	7e-18	96.7
rs:WP_000179664	DNA topoisomerase I [Streptococcus mitis].	24.45	409	236	14	66	452	254	611	7e-18	96.7
rs:WP_039696903	DNA topoisomerase I [Streptococcus equinus].	24.47	425	251	14	49	452	251	626	7e-18	96.7
rs:WP_028508714	DNA topoisomerase I [Ruminococcaceae bacterium AB4001].	26.59	425	257	13	47	452	231	619	7e-18	96.7
rs:WP_043027054	DNA topoisomerase I [Streptococcus suis].	23.52	421	258	11	50	452	239	613	7e-18	96.7
rs:XP_011354260	PREDICTED: DNA topoisomerase 3-beta-1 [Pteropus vampyrus].	24.07	457	266	17	25	453	247	650	7e-18	96.7
tr:H5T9E7_9ALTE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.75	400	229	18	71	452	288	645	7e-18	96.7
rs:WP_012308141	DNA topoisomerase I [Synechococcus sp. PCC 7002].	28.45	348	210	9	41	379	249	566	7e-18	96.7
rs:WP_031447743	DNA topoisomerase I [Caulobacteraceae bacterium PMMR1].	26.33	452	265	15	41	454	224	645	7e-18	96.7
rs:WP_022144615	DNA topoisomerase [Ruminococcus sp. CAG:563].	24.89	474	256	17	40	449	217	654	7e-18	96.7
rs:WP_034336155	DNA topoisomerase I [Commensalibacter sp. MX01].	25.47	424	254	13	61	452	245	638	7e-18	96.7
rs:WP_044822101	DNA topoisomerase I, partial [Bacillus thuringiensis].	29.13	254	141	9	211	457	21	242	7e-18	94.0
rs:WP_033855510	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	7e-18	96.7
rs:WP_027825571	DNA topoisomerase I [Lactobacillus psittaci].	25.06	431	255	15	43	452	224	607	7e-18	96.3
rs:WP_023557169	DNA topoisomerase I [Brevibacillus panacihumi].	24.16	418	258	12	54	452	231	608	7e-18	96.3
rs:WP_002478284	DNA topoisomerase I [Staphylococcus lugdunensis].	24.24	425	261	14	47	452	224	606	7e-18	96.3
rs:WP_041014252	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	24.88	422	267	12	42	452	253	635	7e-18	96.7
tr:A0A0D6ZGG3_LACDE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.79	433	244	17	43	452	254	636	7e-18	96.7
rs:WP_021861600	DNA topoisomerase [Dorea sp. CAG:105].	25.59	426	264	11	48	457	227	615	7e-18	96.3
rs:WP_038052939	DNA topoisomerase I [Thioalkalivibrio sp. ALJ1].	27.84	352	212	7	36	377	233	552	8e-18	96.7
rs:WP_003797825	DNA topoisomerase I [Kingella oralis].	23.23	495	283	11	28	454	215	680	8e-18	96.7
rs:WP_018135954	DNA topoisomerase I [Campylobacter curvus].	26.54	422	246	16	47	450	224	599	8e-18	96.3
rs:WP_003285574	topoisomerase I [Pseudomonas stutzeri].	24.88	422	267	12	42	452	253	635	8e-18	96.7
rs:WP_023918171	DNA topoisomerase 1 [Streptococcus parasanguinis].	23.46	422	258	12	49	452	235	609	8e-18	96.3
rs:WP_016186698	DNA topoisomerase III, partial [Staphylococcus aureus].	28.37	208	138	2	35	236	227	429	8e-18	95.1
rs:WP_017538191	MULTISPECIES: DNA topoisomerase I [Nocardiopsis].	27.12	354	210	11	42	379	276	597	8e-18	96.7
rs:WP_013903584	DNA topoisomerase I [Streptococcus parasanguinis].	23.46	422	258	12	49	452	237	611	8e-18	96.3
rs:WP_043901710	DNA topoisomerase I [Streptococcus sp. DORA_10].	24.45	409	236	14	66	452	239	596	8e-18	96.3
rs:WP_004710690	DNA topoisomerase I [Acinetobacter nosocomialis].	27.17	427	254	19	40	452	266	649	8e-18	96.7
rs:WP_032849228	DNA topoisomerase I, partial [Fusobacterium nucleatum].	26.63	368	215	12	26	377	209	537	8e-18	96.7
rs:WP_011927903	DNA topoisomerase I [Dichelobacter nodosus].	27.98	386	221	12	48	410	237	588	8e-18	96.7
tr:C0N5G6_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.74	429	247	19	46	452	247	634	8e-18	96.7
rs:WP_011191333	MULTISPECIES: DNA topoisomerase [Aeromonas].	26.16	409	241	16	61	455	231	592	8e-18	96.3
rs:WP_048358711	DNA topoisomerase I [Pseudomonas deceptionensis].	27.11	391	232	15	69	446	277	627	8e-18	96.7
rs:WP_036181603	DNA topoisomerase I [Lysinibacillus manganicus].	25.34	446	270	16	34	457	210	614	8e-18	96.3
rs:WP_010430824	topoisomerase I [Pseudomonas syringae].	27.52	407	246	16	49	446	261	627	8e-18	96.7
rs:WP_017393949	MULTISPECIES: topoisomerase I [Acinetobacter calcoaceticus/baumannii complex].	27.17	427	254	19	40	452	266	649	8e-18	96.7
rs:WP_010364821	topoisomerase I [Pseudoalteromonas citrea].	27.50	400	223	16	66	446	280	631	8e-18	96.7
rs:WP_028518733	DNA topoisomerase I [Ruminococcus flavefaciens].	25.06	431	261	12	43	452	221	610	8e-18	96.3
tr:K7HB20_CAEJA	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:CJA21342a};	26.21	412	237	15	70	459	720	1086	8e-18	97.1
tr:K2CW40_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.65	409	239	15	65	452	247	615	8e-18	96.3
rs:WP_028991696	DNA topoisomerase I [Thermoanaerobacter thermocopriae].	25.56	493	278	21	1	454	170	612	8e-18	96.3
tr:A0A081PQQ6_STRMT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.45	409	236	14	66	452	207	564	8e-18	96.3
rs:WP_008691655	DNA topoisomerase I [Fusobacterium nucleatum].	25.96	366	220	10	26	377	212	540	8e-18	96.3
rs:WP_022286871	DNA topoisomerase [Ruminococcus sp. CAG:57].	24.23	421	270	13	47	452	225	611	8e-18	96.3
rs:WP_039574026	DNA topoisomerase I [Sphingopyxis sp. Kp5.2].	26.91	405	234	13	71	452	252	617	8e-18	96.7
rs:WP_003336897	DNA topoisomerase I [Brevibacillus laterosporus].	25.79	473	272	17	18	457	187	613	8e-18	96.3
rs:WP_031573190	DNA topoisomerase I [Streptococcus parasanguinis].	23.46	422	258	12	49	452	235	609	8e-18	96.3
rs:WP_029662198	DNA topoisomerase III [Streptococcus agalactiae].	26.29	350	218	9	57	398	264	581	8e-18	96.3
rs:WP_038281608	DNA topoisomerase I [alpha proteobacterium JLT2015].	27.46	437	247	17	43	454	237	628	8e-18	96.7
tr:K7HB21_CAEJA	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:CJA21342b};	26.21	412	237	15	70	459	720	1086	8e-18	97.1
rs:WP_010629088	topoisomerase I [Halomonas sp. KM-1].	28.39	398	223	16	77	458	296	647	8e-18	96.7
rs:XP_010597196	PREDICTED: DNA topoisomerase 3-beta-1 [Loxodonta africana].	24.04	441	255	16	40	453	263	650	8e-18	96.7
rs:WP_044764051	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	8e-18	96.3
rs:WP_031413665	DNA topoisomerase I [Brevibacillus laterosporus].	25.16	473	275	16	18	457	187	613	8e-18	96.3
rs:WP_022435372	DNA topoisomerase [Firmicutes bacterium CAG:321].	25.26	392	234	13	75	450	249	597	8e-18	96.3
rs:WP_020902794	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.45	409	236	14	66	452	254	611	8e-18	96.3
rs:WP_031952294	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	8e-18	96.7
tr:M2TPP4_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.46	437	247	17	43	454	243	634	8e-18	96.7
tr:A0A0E0B043_9ORYZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.11	438	268	14	39	451	209	611	8e-18	96.7
rs:WP_034285550	DNA topoisomerase I [Bacillus sp. 72].	23.89	452	277	16	25	452	201	609	8e-18	96.3
rs:WP_031906744	DNA topoisomerase I [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	8e-18	96.3
rs:XP_005752308	PREDICTED: DNA topoisomerase 3-alpha-like isoform X2 [Pundamilia nyererei].	23.94	472	273	14	24	456	209	633	8e-18	96.7
rs:WP_037039426	DNA topoisomerase I [Pseudomonas sp. BAY1663].	24.88	422	267	12	42	452	252	634	8e-18	96.7
rs:WP_014334730	DNA topoisomerase I [Streptococcus infantarius].	24.24	429	245	15	50	452	252	626	8e-18	96.3
tr:W1UK62_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.45	409	236	14	66	452	307	664	8e-18	96.3
tr:K7HB22_CAEJA	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:CJA21342c};	26.21	412	237	15	70	459	720	1086	8e-18	97.1
rs:WP_044475278	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	8e-18	96.3
rs:XP_005752307	PREDICTED: DNA topoisomerase 3-alpha-like isoform X1 [Pundamilia nyererei].	23.94	472	273	14	24	456	289	713	8e-18	96.7
rs:XP_005947076	PREDICTED: DNA topoisomerase 3-alpha-like isoform X1 [Haplochromis burtoni].	23.94	472	273	14	24	456	289	713	8e-18	96.7
rs:XP_004669092	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Jaculus jaculus].	25.47	424	248	14	60	455	215	598	8e-18	96.7
rs:WP_032882171	DNA topoisomerase I [Fusobacterium nucleatum].	26.84	354	207	10	40	377	220	537	8e-18	96.3
rs:WP_034058858	DNA topoisomerase I [Pseudomonas aeruginosa].	26.76	411	246	16	60	459	234	600	8e-18	96.3
rs:XP_005947077	PREDICTED: DNA topoisomerase 3-alpha-like isoform X2 [Haplochromis burtoni].	23.94	472	273	14	24	456	209	633	9e-18	96.7
rs:XP_004575543	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Maylandia zebra].	23.94	472	273	14	24	456	209	633	9e-18	96.7
rs:WP_022468862	DNA topoisomerase [Clostridium sp. CAG:451].	23.89	473	267	14	36	455	211	643	9e-18	96.3
rs:WP_006588265	DNA topoisomerase I [Lactobacillus jensenii].	24.77	428	260	14	43	452	224	607	9e-18	96.3
rs:WP_038046302	hypothetical protein [Thermoanaerobaculum aquaticum].	26.38	436	269	14	40	458	218	618	9e-18	96.3
rs:WP_022072993	DNA topoisomerase [Anaerotruncus sp. CAG:528].	22.73	462	261	14	47	449	225	649	9e-18	96.3
rs:WP_011021792	DNA topoisomerase [Methanosarcina acetivorans].	25.62	445	273	18	31	454	235	642	9e-18	96.3
rs:WP_044941940	DNA topoisomerase I [Flavonifractor plautii].	25.74	439	271	13	34	454	214	615	9e-18	96.3
rs:WP_003458909	DNA topoisomerase III [Clostridium perfringens].	26.95	371	218	16	98	452	306	639	9e-18	96.3
rs:WP_031646389	DNA topoisomerase I, partial [Listeria monocytogenes].	25.74	408	230	17	71	452	14	374	9e-18	95.5
tr:W4L4A1_9DELT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETW92867.1}; Flags: Fragment;	26.85	298	181	10	166	452	25	296	9e-18	93.6
rs:XP_007054991	PREDICTED: DNA topoisomerase 3-beta-1 [Chelonia mydas].	24.26	441	254	16	40	453	263	650	9e-18	96.3
rs:WP_022060820	DNA topoisomerase [Corallococcus sp. CAG:1435].	24.31	469	259	19	47	454	225	658	9e-18	96.3
rs:XP_004575542	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Maylandia zebra].	23.94	472	273	14	24	456	289	713	9e-18	96.7
rs:WP_035634529	DNA topoisomerase I [Lachnospiraceae bacterium ND2006].	25.23	436	272	13	35	454	218	615	9e-18	96.3
rs:WP_028484168	DNA topoisomerase I [Thioalkalivibrio sp. ALE17].	28.61	360	210	9	36	377	233	563	9e-18	96.3
rs:WP_033196594	DNA topoisomerase III, partial [Bacillus oceanisediminis].	27.76	263	148	7	189	446	1	226	9e-18	93.6
rs:WP_033102341	DNA topoisomerase I [Thermoactinomyces daqus].	24.35	464	290	13	18	457	187	613	9e-18	96.3
rs:WP_024791594	DNA topoisomerase I [Lebetimonas sp. JS032].	24.24	425	258	12	47	454	224	601	9e-18	96.3
rs:WP_041041004	DNA topoisomerase I [Tolypothrix campylonemoides].	25.18	417	250	14	40	435	240	615	9e-18	96.3
rs:WP_006738721	DNA topoisomerase I [Streptococcus urinalis].	24.51	412	243	14	61	452	261	624	9e-18	96.3
rs:WP_043878370	DNA topoisomerase I [Streptococcus infantarius].	24.24	429	245	15	50	452	252	626	9e-18	96.3
rs:WP_029175455	DNA topoisomerase I [Streptococcus suis].	24.15	439	266	13	34	452	222	613	9e-18	96.3
rs:WP_004842577	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	9e-18	96.3
rs:WP_029457032	DNA topoisomerase I [Desulfovibrio alcoholivorans].	25.96	416	248	14	54	452	232	604	9e-18	96.3
rs:WP_032654924	DNA topoisomerase I [Pseudomonas syringae].	28.22	411	238	18	49	446	261	627	9e-18	96.3
rs:WP_044754361	DNA topoisomerase I [Streptococcus suis].	24.15	439	266	13	34	452	222	613	9e-18	96.3
rs:XP_008820178	PREDICTED: DNA topoisomerase 3-alpha [Nannospalax galili].	25.56	446	261	16	40	455	289	693	9e-18	96.7
rs:XP_004669091	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Jaculus jaculus].	25.47	424	248	14	60	455	310	693	9e-18	96.7
rs:WP_024385241	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	9e-18	96.3
rs:WP_042272078	DNA topoisomerase I [Clostridium sp. 01].	22.30	426	271	10	46	454	225	607	9e-18	96.3
rs:WP_033687089	DNA topoisomerase I [Streptococcus mitis].	24.21	409	237	14	66	452	236	593	9e-18	96.3
tr:A0A0D1JJ80_9LACT	SubName: Full=TopB_2 protein {ECO:0000313|EMBL:KIU21473.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIU21473.1};	33.16	193	108	6	278	454	10	197	9e-18	92.4
rs:WP_044684533	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	9e-18	96.3
rs:WP_005213329	DNA topoisomerase I [Clostridium celatum].	24.62	459	252	17	47	449	224	644	9e-18	96.3
tr:X8IR60_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.41	440	249	14	68	455	264	667	9e-18	96.3
rs:WP_033681703	DNA topoisomerase I [Streptococcus mitis].	24.45	409	236	14	66	452	236	593	9e-18	96.3
rs:WP_020901448	DNA topoisomerase I [Streptococcus mitis].	24.45	409	236	14	66	452	254	611	9e-18	96.3
rs:WP_012961976	DNA topoisomerase I [Streptococcus gallolyticus].	23.81	420	258	12	50	452	253	627	9e-18	96.3
rs:WP_011922475	DNA topoisomerase I [Streptococcus suis].	24.82	423	251	12	50	452	254	629	9e-18	96.3
rs:WP_022081022	DNA topoisomerase [Ruminococcus sp. CAG:488].	25.32	474	254	18	40	449	217	654	9e-18	96.3
rs:WP_040260718	DNA topoisomerase I [Pseudomonas sp. CB1].	25.51	396	234	11	68	446	273	624	9e-18	96.3
rs:WP_000179653	DNA topoisomerase I [Streptococcus mitis].	24.20	405	242	12	66	452	254	611	9e-18	96.3
rs:WP_040223164	DNA topoisomerase III, partial [Klebsiella pneumoniae].	30.66	212	120	6	264	459	27	227	9e-18	93.6
gp:CP000446_1580	DNA topoisomerase I [Shewanella sp. MR-4]	26.00	450	270	17	10	446	248	647	9e-18	96.3
rs:WP_003341403	DNA topoisomerase I [Brevibacillus laterosporus].	25.79	473	272	17	18	457	187	613	9e-18	96.3
rs:WP_024641788	DNA topoisomerase I [Pseudomonas syringae].	28.22	411	238	18	49	446	261	627	9e-18	96.3
rs:WP_032051078	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	9e-18	96.3
rs:WP_048130263	MULTISPECIES: DNA topoisomerase [Methanosarcina].	25.66	456	253	19	34	454	238	642	9e-18	96.3
rs:WP_011268332	DNA topoisomerase I [Pseudomonas syringae].	28.22	411	238	18	49	446	261	627	9e-18	96.3
rs:WP_037624562	DNA topoisomerase I [Streptococcus uberis].	22.33	421	263	11	50	452	251	625	9e-18	96.3
rs:WP_045651823	DNA topoisomerase I [Gammaproteobacteria bacterium BRH_c0].	26.67	420	257	17	36	446	254	631	9e-18	96.3
rs:WP_048514850	DNA topoisomerase I [Megasphaera cerevisiae].	25.92	409	236	14	65	452	306	668	9e-18	96.3
rs:WP_034663111	DNA topoisomerase I [Corynebacterium tuscaniense].	27.59	377	209	13	35	384	247	586	1e-17	96.3
rs:XP_006649448	PREDICTED: DNA topoisomerase 3-alpha-like [Oryza brachyantha].	26.01	446	257	16	39	452	270	674	1e-17	96.3
rs:WP_006746967	DNA topoisomerase I [Thioalkalivibrio thiocyanoxidans].	28.95	342	182	13	31	350	221	523	1e-17	96.3
rs:WP_005974558	DNA topoisomerase I [Fusobacterium periodonticum].	27.24	323	188	9	69	377	251	540	1e-17	96.3
rs:WP_044672450	DNA topoisomerase I [Streptococcus suis].	24.15	439	266	13	34	452	222	613	1e-17	96.3
rs:WP_043895033	DNA topoisomerase I [Streptococcus lutetiensis].	23.99	421	258	12	49	452	251	626	1e-17	96.3
rs:WP_044775889	DNA topoisomerase I [Streptococcus suis].	24.15	439	266	13	34	452	222	613	1e-17	96.3
rs:WP_041760312	DNA topoisomerase I [Pseudonocardia dioxanivorans].	28.66	335	193	9	35	354	240	543	1e-17	96.3
rs:WP_016820944	DNA topoisomerase I [Paenibacillus polymyxa].	25.67	413	247	15	65	457	242	614	1e-17	96.3
gp:CP000408_998	DNA topoisomerase I [Streptococcus suis 98HAH33]	24.41	422	253	12	50	452	191	565	1e-17	95.9
tr:B1SFB3_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.24	429	245	15	50	452	270	644	1e-17	96.3
rs:WP_044762088	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	96.3
rs:WP_024385723	DNA topoisomerase I [Streptococcus suis].	23.92	439	267	13	34	452	222	613	1e-17	96.3
rs:XP_006522060	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Mus musculus].	23.85	457	267	17	25	453	247	650	1e-17	96.3
rs:WP_003403702	topoisomerase I [Pseudomonas syringae].	28.22	411	238	18	49	446	261	627	1e-17	96.3
rs:WP_045434151	hypothetical protein [bacterium UASB270].	25.92	409	247	14	71	454	253	630	1e-17	96.3
rs:WP_048066264	DNA topoisomerase, partial [Methanosarcina acetivorans].	25.62	445	273	18	31	454	235	642	1e-17	96.3
rs:WP_012775128	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.9
rs:WP_009708791	DNA topoisomerase I [Desmospora sp. 8437].	23.97	438	271	13	41	457	218	614	1e-17	95.9
rs:WP_027232501	DNA topoisomerase I [Phyllobacterium sp. UNC302MFCol5.2].	28.01	407	231	15	77	452	260	635	1e-17	96.3
rs:WP_006734849	DNA topoisomerase [Lactobacillus iners].	24.26	408	276	12	61	445	277	674	1e-17	96.3
rs:XP_005077629	PREDICTED: DNA topoisomerase 3-beta-1 [Mesocricetus auratus].	23.85	457	267	17	25	453	247	650	1e-17	96.3
rs:WP_029998768	DNA topoisomerase I [Streptococcus suis].	24.15	439	266	13	34	452	222	613	1e-17	95.9
rs:WP_025905317	DNA topoisomerase I [Staphylococcus sciuri].	26.07	399	229	16	76	452	253	607	1e-17	95.9
rs:WP_000259047	MULTISPECIES: DNA topoisomerase III [Streptococcus].	26.08	372	240	11	18	385	223	563	1e-17	95.9
tr:J3LKB1_ORYBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.01	446	257	16	39	452	270	674	1e-17	96.3
rs:WP_039728455	MULTISPECIES: DNA topoisomerase I [Oscillatoriophycideae].	28.61	353	203	12	41	379	249	566	1e-17	96.3
rs:WP_020033631	hypothetical protein [Oceanospirillales bacterium SCGC AAA298-N10].	24.68	393	245	11	77	458	286	638	1e-17	96.3
rs:WP_031961607	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	1e-17	96.3
rs:WP_005245924	DNA topoisomerase I [Acinetobacter sp. CIP 51.11].	27.41	321	193	10	40	356	268	552	1e-17	96.3
rs:XP_008248583	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha [Oryctolagus cuniculus].	25.94	424	246	14	60	455	311	694	1e-17	96.3
rs:WP_002459295	DNA topoisomerase I [Staphylococcus lugdunensis].	24.24	425	261	14	47	452	224	606	1e-17	95.9
rs:WP_014500347	DNA topoisomerase I [Zymomonas mobilis].	26.56	433	265	14	41	452	222	622	1e-17	96.3
rs:WP_011678373	DNA topoisomerase I [Lactobacillus delbrueckii].	26.56	433	246	17	43	452	252	635	1e-17	95.9
rs:WP_003618692	DNA topoisomerase I [Lactobacillus delbrueckii].	26.56	433	246	17	43	452	254	637	1e-17	95.9
rs:WP_024795083	DNA topoisomerase I [Tomitella biformata].	26.91	405	238	14	41	419	264	636	1e-17	96.3
rs:WP_023918843	DNA topoisomerase I [Rhodobacter capsulatus].	25.81	430	263	13	47	454	228	623	1e-17	96.3
rs:WP_016657559	DNA topoisomerase I [Acinetobacter rudis].	25.88	456	275	19	18	452	236	649	1e-17	96.3
rs:WP_015694903	DNA topoisomerase I [Melissococcus plutonius].	24.58	419	252	15	61	457	239	615	1e-17	95.9
rs:WP_000259048	DNA topoisomerase III [Streptococcus agalactiae].	26.08	372	240	11	18	385	221	561	1e-17	95.9
rs:WP_027966615	DNA topoisomerase I [Halomonas halocynthiae].	28.15	405	228	18	70	458	291	648	1e-17	96.3
tr:R0MTD2_STRMT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.45	409	236	14	66	452	202	559	1e-17	95.9
rs:WP_037545865	DNA topoisomerase I [Staphylococcus lugdunensis].	24.24	425	261	14	47	452	224	606	1e-17	95.9
rs:WP_006008809	DNA topoisomerase I [Desulfovibrio piger].	25.42	421	244	14	54	452	232	604	1e-17	95.9
rs:WP_034434629	DNA topoisomerase I [Clostridiales bacterium S5-A14a].	22.66	459	265	12	48	453	232	653	1e-17	95.9
rs:WP_017768091	DNA topoisomerase III [Streptococcus agalactiae].	26.08	372	240	11	18	385	223	563	1e-17	95.9
rs:WP_018705151	DNA topoisomerase I [Bacillus fordii].	26.21	435	246	19	50	457	227	613	1e-17	95.9
rs:WP_008570827	topoisomerase I [Pseudomonas sp. Chol1].	25.62	402	243	13	68	452	273	635	1e-17	96.3
rs:XP_004433056	PREDICTED: DNA topoisomerase 3-alpha [Ceratotherium simum simum].	25.39	445	263	15	40	455	289	693	1e-17	96.3
rs:XP_005620201	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Canis lupus familiaris].	25.94	424	246	14	60	455	290	673	1e-17	96.3
rs:WP_036381104	DNA topoisomerase I [Mogibacterium timidum].	23.41	440	249	14	68	455	237	640	1e-17	95.9
rs:WP_046439302	DNA topoisomerase I [Ruminococcus sp. N15.MGS-57].	24.23	421	270	13	47	452	225	611	1e-17	95.9
rs:WP_024376241	DNA topoisomerase I [Streptococcus suis].	24.15	439	266	13	34	452	222	613	1e-17	95.9
rs:XP_012579341	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Condylura cristata].	24.10	444	251	17	40	453	263	650	1e-17	95.9
rs:XP_004466517	PREDICTED: DNA topoisomerase 3-beta-1 [Dasypus novemcinctus].	23.63	457	268	17	25	453	247	650	1e-17	96.3
rs:WP_013944621	DNA topoisomerase I [Simkania negevensis].	25.29	435	252	14	47	454	244	632	1e-17	96.3
rs:WP_019624066	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	28.41	359	201	9	36	377	233	552	1e-17	96.3
rs:WP_018864622	DNA topoisomerase I [Thioalkalivibrio sp. ARh3].	28.88	329	181	8	36	350	233	522	1e-17	96.3
rs:WP_044785597	DNA topoisomerase I [Paenibacillus polymyxa].	25.67	413	247	15	65	457	242	614	1e-17	95.9
rs:WP_019893231	hypothetical protein [Allobaculum stercoricanis].	24.03	437	261	11	40	452	219	608	1e-17	95.9
rs:WP_045582096	DNA topoisomerase I [Azospirillum thiophilum].	26.47	476	273	16	17	454	204	640	1e-17	96.3
rs:WP_023946902	DNA topoisomerase I [Streptococcus mitis].	24.45	409	236	14	66	452	254	611	1e-17	95.9
rs:XP_546656	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Canis lupus familiaris].	25.94	424	246	14	60	455	310	693	1e-17	96.3
gp:CP009316_1	DNA topoisomerase family protein [Bacillus anthracis str. Turkey32]	25.28	265	183	6	193	454	1	253	1e-17	95.5
rs:WP_041455453	DNA topoisomerase I [Anaerolinea thermophila].	23.22	435	287	8	41	457	216	621	1e-17	95.9
rs:WP_024408846	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.9
rs:WP_014313953	DNA topoisomerase I [Clostridium sp. BNL1100].	25.05	467	278	17	22	454	191	619	1e-17	95.9
rs:WP_022466959	DNA topoisomerase [Subdoligranulum sp. CAG:314].	26.54	437	261	16	40	459	217	610	1e-17	95.9
rs:WP_044693788	DNA topoisomerase I, partial [Streptococcus suis].	23.92	439	267	13	34	452	222	613	1e-17	95.9
rs:WP_034290689	DNA topoisomerase I [Helicobacter sp. MIT 11-5569].	25.53	427	256	14	41	450	224	605	1e-17	95.9
tr:F4CIS0_PSEUX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.66	335	193	9	35	354	281	584	1e-17	96.3
rs:WP_018868630	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	27.82	399	223	11	3	377	195	552	1e-17	96.3
rs:WP_018862529	DNA topoisomerase I [Thioalkalivibrio sp. ALJ3].	27.82	399	223	11	3	377	195	552	1e-17	96.3
rs:WP_027705141	DNA topoisomerase I [Zymobacter palmae].	28.36	409	232	18	69	458	282	648	1e-17	96.3
rs:WP_015615734	DNA topoisomerase I [Clostridium pasteurianum].	24.94	433	254	17	46	454	225	610	1e-17	95.9
rs:WP_032576660	DNA topoisomerase I, partial [Bacteroides fragilis].	25.45	334	197	10	79	395	7	305	1e-17	93.2
rs:WP_032881893	DNA topoisomerase I [Fusobacterium hwasookii].	27.07	351	201	11	61	391	240	555	1e-17	95.9
tr:A0A0E3NPL6_9EURY	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:AKB21424.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AKB21424.1};	25.66	456	253	19	34	454	276	680	1e-17	95.9
rs:WP_033677361	DNA topoisomerase I [Streptococcus mitis].	24.45	409	236	14	66	452	254	611	1e-17	95.9
rs:WP_013822097	DNA topoisomerase I [Desulfotomaculum kuznetsovii].	24.44	446	268	17	36	457	214	614	1e-17	95.9
rs:WP_044762879	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.9
rs:WP_028491545	DNA topoisomerase I [Thioalkalivibrio sp. ALE19].	28.13	359	202	9	36	377	233	552	1e-17	96.3
rs:WP_023920771	DNA topoisomerase I [Rhodobacter capsulatus].	25.81	430	263	13	47	454	228	623	1e-17	96.3
rs:WP_015891767	DNA topoisomerase I [Brevibacillus brevis].	24.54	432	259	15	49	457	226	613	1e-17	95.9
rs:WP_003139282	DNA topoisomerase I [Lactococcus raffinolactis].	24.22	417	240	13	60	452	269	633	1e-17	95.9
rs:WP_018873178	DNA topoisomerase I [Thioalkalivibrio sp. ALJ16].	27.82	399	223	11	3	377	195	552	1e-17	96.3
rs:WP_034442673	DNA topoisomerase I [Butyrivibrio sp. AE2032].	26.59	425	257	12	47	452	231	619	1e-17	95.9
rs:WP_027486209	DNA topoisomerase I [Rhizobium undicola].	26.47	442	257	16	46	452	229	637	1e-17	96.3
rs:WP_000024265	DNA topoisomerase I subunit omega [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	1e-17	96.3
rs:WP_018141432	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	28.41	345	197	9	61	384	248	563	1e-17	96.3
rs:WP_018286108	hypothetical protein [zeta proteobacterium SCGC AB-137-I08].	27.10	417	240	16	60	454	243	617	1e-17	95.9
rs:WP_047305771	DNA topoisomerase I [Pseudomonas fluorescens].	25.88	398	247	15	77	459	263	627	1e-17	95.9
rs:WP_005992671	DNA topoisomerase I [Desulfovibrio fructosivorans].	25.72	416	249	13	54	452	232	604	1e-17	95.9
rs:WP_023060391	DNA topoisomerase I subunit omega [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	1e-17	95.9
rs:WP_013325931	DNA topoisomerase I [Sulfurimonas autotrophica].	24.07	428	254	13	47	452	225	603	1e-17	95.9
rs:WP_045597118	DNA topoisomerase I [Streptococcus mitis].	24.21	409	237	14	66	452	254	611	1e-17	95.9
tr:S5QX37_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.99	421	258	12	49	452	269	644	1e-17	95.9
rs:NP_001099331	DNA topoisomerase 3-beta-1 [Rattus norvegicus].	23.85	457	267	17	25	453	247	650	1e-17	95.9
rs:WP_044775437	DNA topoisomerase I [Streptococcus suis].	24.15	439	266	13	34	452	222	613	1e-17	95.9
rs:WP_013068797	DNA topoisomerase I [Rhodobacter capsulatus].	25.81	430	263	13	47	454	228	623	1e-17	95.9
rs:WP_047909729	DNA topoisomerase I [Paenibacillus sp. TCA20].	24.71	433	258	15	50	458	227	615	1e-17	95.9
rs:WP_032894880	DNA topoisomerase I [Fusobacterium hwasookii].	27.07	351	201	11	61	391	240	555	1e-17	95.9
rs:WP_023611066	DNA topoisomerase I [Streptococcus pyogenes].	23.46	422	257	14	50	452	250	624	1e-17	95.9
rs:WP_024380821	DNA topoisomerase I [Streptococcus suis].	24.17	422	254	12	50	452	239	613	1e-17	95.9
tr:H5SCU4_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.90	417	235	16	61	450	284	653	1e-17	95.9
rs:WP_043864567	DNA topoisomerase I [Pseudomonas putida].	26.63	413	254	12	42	446	254	625	1e-17	95.9
rs:XP_003465949	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Cavia porcellus].	25.51	443	265	16	40	455	289	693	1e-17	96.3
rs:WP_032577053	DNA topoisomerase I, partial [Bacteroides fragilis].	24.17	393	242	12	21	394	56	411	1e-17	94.7
rs:WP_013495388	DNA topoisomerase I [Thermaerobacter marianensis].	24.95	473	269	16	36	452	213	655	1e-17	95.9
rs:WP_044689880	DNA topoisomerase I [Streptococcus suis].	24.15	439	266	13	34	452	222	613	1e-17	95.9
gp:AF088896_23	topoisomerase I [Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821]	26.09	437	262	14	41	452	227	627	1e-17	96.3
rs:WP_000445595	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	236	593	1e-17	95.9
rs:WP_026747454	DNA topoisomerase [Leptotrichia trevisanii].	25.77	392	244	14	74	452	268	625	1e-17	95.9
rs:XP_012013093	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Ovis aries musimon].	24.04	441	255	16	40	453	263	650	1e-17	95.9
rs:WP_029171748	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.9
rs:WP_032062207	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	1e-17	95.9
rs:WP_032025980	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	1e-17	95.9
rs:WP_044934103	DNA topoisomerase I [Pseudobutyrivibrio sp. LB2011].	22.78	439	286	12	36	457	213	615	1e-17	95.9
rs:XP_006798035	PREDICTED: DNA topoisomerase 3-alpha-like [Neolamprologus brichardi].	24.15	472	272	14	24	456	289	713	1e-17	96.3
rs:WP_024329307	DNA topoisomerase I [Thioalkalivibrio sp. ALR17-21].	28.57	329	182	8	36	350	233	522	1e-17	95.9
rs:WP_004231665	DNA topoisomerase I [Streptococcus equinus].	24.29	424	251	14	50	452	252	626	1e-17	95.9
rs:WP_013978147	DNA topoisomerase I [Clostridium sp. SY8519].	25.81	430	258	16	47	457	226	613	1e-17	95.9
rs:WP_011992733	DNA topoisomerase I [Campylobacter curvus].	26.54	422	246	16	47	450	224	599	1e-17	95.9
rs:WP_023370336	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.9
rs:WP_000024260	topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	1e-17	95.9
rs:WP_047210003	DNA topoisomerase [Streptococcus agalactiae].	27.25	334	199	10	61	385	265	563	1e-17	95.5
rs:WP_013155942	DNA topoisomerase I [Nocardiopsis dassonvillei].	26.33	357	213	11	40	379	275	598	1e-17	95.9
rs:WP_019424975	DNA topoisomerase I [Paenibacillus sp. OSY-SE].	24.10	444	278	13	34	457	210	614	1e-17	95.9
rs:WP_004195696	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.9
rs:WP_024407141	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.9
rs:WP_024394484	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.9
rs:WP_024390017	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.9
rs:WP_015646822	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.9
rs:WP_041409019	DNA topoisomerase I [Shewanella sp. MR-4].	26.00	450	270	17	10	446	232	631	1e-17	95.9
rs:WP_031979792	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	1e-17	95.9
tr:A0A090WAW1_9FLAO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL72564.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL72564.1};	28.92	249	148	9	221	454	17	251	1e-17	94.0
rs:WP_038522534	DNA topoisomerase I [Lactobacillus sp. wkB8].	25.00	436	263	15	38	452	221	613	1e-17	95.9
rs:WP_008089323	DNA topoisomerase I [Streptococcus ictaluri].	22.75	422	260	12	50	452	251	625	1e-17	95.9
rs:WP_021997716	DNA topoisomerase [Ruminococcus sp. CAG:724].	24.14	435	254	13	50	446	255	651	1e-17	95.9
rs:WP_037534984	DNA topoisomerase I [Sphingomonas sp. RIT328].	28.05	467	273	18	7	452	193	617	1e-17	95.9
tr:A0A0B3AKA5_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.56	399	226	17	77	453	404	753	1e-17	95.9
tr:C0EHG4_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.17	427	249	18	47	452	239	624	1e-17	95.9
rs:WP_035111286	DNA topoisomerase I [Corynebacterium freiburgense].	26.33	376	225	10	31	386	251	594	1e-17	95.9
rs:WP_024400616	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.9
rs:XP_010850479	PREDICTED: DNA topoisomerase 3-beta-1 [Bison bison bison].	24.04	441	255	16	40	453	263	650	1e-17	95.9
rs:XP_006774025	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Myotis davidii].	25.78	419	241	13	60	450	259	635	1e-17	95.9
rs:WP_024417185	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.9
rs:WP_009212596	DNA topoisomerase I [Actinomyces sp. oral taxon 180].	27.40	365	219	11	42	385	253	592	1e-17	95.9
rs:WP_013788113	DNA topoisomerase I [Thermoanaerobacterium xylanolyticum].	26.76	411	228	16	69	454	247	609	1e-17	95.9
rs:WP_045611818	DNA topoisomerase I [Streptococcus mitis].	24.45	409	236	14	66	452	254	611	1e-17	95.9
rs:WP_039683338	DNA topoisomerase I [Tateyamaria sp. ANG-S1].	28.47	411	230	16	71	454	255	628	1e-17	95.9
rs:WP_044755138	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.9
tr:D1YJE5_LACGS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.06	407	243	15	69	457	205	567	1e-17	95.5
tr:A0A098FAS6_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.53	425	270	13	50	457	227	613	1e-17	95.9
rs:WP_006727604	DNA topoisomerase I [Agrobacterium albertimagni].	26.74	445	252	15	47	452	230	639	1e-17	95.9
rs:WP_032511243	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.9
tr:K9J3S6_DESRO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.18	424	245	14	60	455	148	531	1e-17	95.9
rs:WP_016803628	topoisomerase I [Acinetobacter nosocomialis].	27.17	427	254	19	40	452	266	649	1e-17	95.9
rs:WP_041104791	DNA topoisomerase I [Pseudomonas stutzeri].	26.49	419	256	14	47	452	254	633	1e-17	95.9
tr:Q0HW50_SHESR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.00	450	270	17	10	446	248	647	1e-17	95.9
rs:WP_027851694	DNA topoisomerase III [Marinospirillum insulare].	27.23	382	251	13	31	392	253	627	1e-17	95.9
rs:WP_002353633	hypothetical protein, partial [Enterococcus faecium].	35.90	156	91	3	210	365	1	147	1e-17	92.8
rs:WP_044308551	DNA topoisomerase I [Pseudomonas syringae].	27.52	407	246	16	49	446	261	627	1e-17	95.9
tr:W8BLV1_CERCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.33	454	257	18	37	451	278	688	1e-17	95.9
rs:WP_044768045	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.5
rs:WP_024383462	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.5
rs:WP_004692508	DNA topoisomerase I [Acinetobacter johnsonii].	26.70	427	256	19	40	452	268	651	1e-17	95.9
rs:WP_020059168	DNA topoisomerase I [Bacillus sp. 123MFChir2].	23.15	445	280	14	34	457	210	613	1e-17	95.5
rs:WP_014835855	DNA topoisomerase I [Corynebacterium ulcerans].	26.42	371	226	11	31	384	249	589	1e-17	95.9
rs:WP_044766305	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.5
rs:WP_023454501	DNA topoisomerase I [Asticcacaulis sp. AC460].	26.12	402	227	13	86	454	268	632	1e-17	95.9
rs:WP_012656741	DNA topoisomerase I [Macrococcus caseolyticus].	25.12	422	256	14	49	452	226	605	1e-17	95.5
rs:WP_019610476	DNA topoisomerase I [Nocardiopsis sp. CNS639].	26.33	357	213	11	40	379	275	598	1e-17	95.9
rs:WP_024410540	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.5
tr:G1SQY7_RABIT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.94	424	246	14	60	455	311	694	1e-17	95.9
rs:WP_031950010	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	1e-17	95.9
tr:T0TG73_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.29	424	251	14	50	452	220	594	1e-17	95.5
rs:WP_024434017	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	1e-17	95.9
tr:F6QNQ6_MACMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.07	457	266	17	25	453	247	650	1e-17	95.5
rs:WP_031534466	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.94	433	244	19	50	452	227	608	1e-17	95.5
rs:WP_040438574	DNA topoisomerase I [[Clostridium] methylpentosum].	27.17	427	249	18	47	452	230	615	1e-17	95.5
rs:WP_012646645	DNA topoisomerase I [Geobacter daltonii].	26.09	414	237	15	65	454	250	618	1e-17	95.9
rs:WP_046327098	DNA topoisomerase I [Lactobacillus helsingborgensis].	25.62	402	238	14	69	452	255	613	1e-17	95.5
rs:WP_032068885	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	1e-17	95.9
rs:WP_032025368	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	1e-17	95.9
tr:L8HVJ0_9CETA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.04	441	255	16	40	453	263	650	1e-17	95.9
rs:XP_011738036	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Macaca nemestrina].	24.07	457	266	17	25	453	111	514	1e-17	95.5
rs:WP_000179680	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	1e-17	95.5
rs:WP_000179642	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	1e-17	95.5
rs:WP_024398072	DNA topoisomerase I [Streptococcus suis].	24.15	439	266	13	34	452	222	613	1e-17	95.5
rs:WP_021951438	DNA topoisomerase [Clostridium sp. CAG:678].	23.43	461	259	16	47	449	225	649	1e-17	95.5
rs:WP_023634983	DNA topoisomerase I [Corynebacterium ulcerans].	26.42	371	226	11	31	384	249	589	1e-17	95.9
rs:WP_022129322	DNA topoisomerase [Bacteroides sp. CAG:530].	27.24	290	179	6	47	334	219	478	1e-17	95.9
rs:WP_024388699	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.5
rs:WP_031994669	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	1e-17	95.9
rs:WP_031965029	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	1e-17	95.9
tr:A0A087PLJ9_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.53	425	233	18	65	452	250	636	1e-17	95.9
rs:WP_024791993	DNA topoisomerase I [Lebetimonas sp. JS138].	24.24	425	258	12	47	454	224	601	1e-17	95.5
rs:WP_037987568	DNA topoisomerase I [Thalassospira permensis].	25.77	423	245	16	65	454	248	634	1e-17	95.9
rs:WP_000179651	DNA topoisomerase I [Streptococcus pneumoniae].	24.20	405	242	12	66	452	254	611	1e-17	95.5
rs:WP_044771417	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.5
rs:WP_000309895	hypothetical protein, partial [Shigella boydii].	36.49	148	85	4	303	450	1	139	1e-17	90.1
rs:WP_031959721	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	1e-17	95.9
rs:WP_033897283	DNA topoisomerase I [Pseudomonas sp. FH1].	23.94	401	263	11	70	459	254	623	1e-17	95.5
rs:XP_009235101	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Pongo abelii].	24.07	457	266	17	25	453	129	532	1e-17	95.5
rs:WP_000774785	DNA topoisomerase 1 [Staphylococcus aureus].	25.17	429	252	19	47	452	224	606	1e-17	95.5
rs:WP_002485347	DNA topoisomerase I [Staphylococcus epidermidis].	24.35	423	257	15	50	452	227	606	1e-17	95.5
rs:WP_010325857	topoisomerase I [Acinetobacter lwoffii].	26.70	427	256	19	40	452	268	651	1e-17	95.9
rs:WP_003456255	DNA topoisomerase I [Pseudomonas pseudoalcaligenes].	25.83	391	239	12	68	446	274	625	1e-17	95.9
rs:WP_014294544	DNA topoisomerase I [Streptococcus macedonicus].	23.81	420	258	12	50	452	253	627	1e-17	95.5
rs:WP_044769796	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.5
rs:WP_032017180	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	1e-17	95.9
rs:WP_019638089	DNA topoisomerase I [Paenibacillus fonticola].	23.80	437	273	15	41	457	218	614	1e-17	95.5
rs:WP_009807374	DNA topoisomerase I [Oceanicola batsensis].	28.51	442	249	17	41	454	225	627	1e-17	95.9
rs:WP_041089031	DNA topoisomerase I [Jeotgalibacillus soli Cunha et al. 2012].	24.77	432	259	17	49	457	226	614	1e-17	95.5
rs:XP_004612924	PREDICTED: DNA topoisomerase 3-alpha [Sorex araneus].	25.47	424	248	14	60	455	293	676	1e-17	95.9
rs:WP_037019380	DNA topoisomerase I [Pseudomonas lutea].	25.31	490	264	20	27	458	223	668	1e-17	95.5
rs:WP_044670821	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.5
rs:WP_044667700	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.5
rs:WP_029173296	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.5
rs:WP_000024268	topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	1e-17	95.9
rs:WP_018369651	DNA topoisomerase I [Streptococcus marimammalium].	24.04	445	269	18	29	452	218	614	1e-17	95.5
rs:WP_009119214	DNA topoisomerase I [Neisseria shayeganii].	25.58	430	264	12	41	452	225	616	1e-17	95.5
rs:WP_044979376	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	1e-17	95.5
rs:WP_031972313	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	1e-17	95.9
tr:V6V9G4_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.61	206	140	4	36	238	245	448	1e-17	94.7
rs:WP_003648735	DNA topoisomerase I [Lactobacillus gasseri].	25.12	406	242	15	70	457	253	614	1e-17	95.5
rs:WP_016265142	DNA topoisomerase I [Lactobacillus sakei].	26.28	430	257	15	43	452	222	611	1e-17	95.5
rs:XP_011738035	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Macaca nemestrina].	24.07	457	266	17	25	453	186	589	1e-17	95.5
rs:WP_043553201	DNA topoisomerase I, partial [Acetobacter malorum].	27.53	425	233	18	65	452	250	636	1e-17	95.9
rs:XP_012139435	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Megachile rotundata].	24.89	466	279	16	18	452	1030	1455	1e-17	95.9
rs:WP_018946671	DNA topoisomerase I [Thioalkalivibrio sp. AKL17].	28.57	329	182	8	36	350	233	522	1e-17	95.9
rs:WP_000024261	topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	1e-17	95.9
rs:WP_032054351	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	1e-17	95.9
rs:WP_022439538	DNA topoisomerase [Clostridium sp. CAG:411].	25.30	415	251	12	61	457	240	613	1e-17	95.5
rs:WP_003354565	DNA topoisomerase I [Bacillus smithii].	23.47	426	269	13	50	457	227	613	1e-17	95.5
rs:WP_016201111	DNA topoisomerase I [Bacillus nealsonii].	25.59	426	250	18	50	452	228	609	2e-17	95.5
rs:XP_006774024	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Myotis davidii].	25.76	427	245	14	60	456	310	694	2e-17	95.9
tr:E8N5B1_ANATU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.22	435	287	8	41	457	287	692	2e-17	95.5
rs:WP_009849879	DNA topoisomerase I [Mariprofundus ferrooxydans].	24.94	453	243	15	62	454	250	665	2e-17	95.5
rs:WP_000024270	DNA topoisomerase I subunit omega [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	2e-17	95.9
rs:WP_002132868	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	2e-17	95.9
rs:WP_031974178	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	2e-17	95.9
rs:WP_031966320	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	2e-17	95.9
rs:WP_004748376	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	2e-17	95.9
tr:K9INH6_DESRO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.18	424	245	14	60	455	310	693	2e-17	95.9
rs:WP_045515241	DNA topoisomerase I [Bacillus niacini].	23.38	432	258	16	47	452	225	609	2e-17	95.5
rs:WP_040981465	DNA topoisomerase I [Mesorhizobium plurifarium].	26.34	448	258	19	41	452	224	635	2e-17	95.5
rs:WP_042749308	DNA topoisomerase I, partial [Lactobacillus gasseri].	25.06	407	243	15	69	457	247	609	2e-17	95.5
rs:WP_029669905	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	236	593	2e-17	95.5
rs:WP_019189987	hypothetical protein [Clostridiales bacterium 9403326].	22.68	463	269	10	38	449	219	643	2e-17	95.5
tr:A0A0E3PEB1_9EURY	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:AKB32908.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AKB32908.1};	25.17	445	275	18	31	454	235	642	2e-17	95.5
rs:WP_000179663	DNA topoisomerase I [Streptococcus mitis].	24.21	409	237	14	66	452	254	611	2e-17	95.5
rs:WP_024575122	MULTISPECIES: DNA topoisomerase I [Afipia].	26.25	419	241	14	70	454	253	637	2e-17	95.9
rs:WP_031994209	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	2e-17	95.5
rs:WP_009560096	DNA topoisomerase I [Lactobacillus pasteurii].	25.23	428	254	14	51	454	240	625	2e-17	95.5
rs:WP_000179681	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	2e-17	95.5
tr:K9IP36_DESRO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.04	441	255	16	40	453	263	650	2e-17	95.5
rs:XP_006894616	PREDICTED: DNA topoisomerase 3-beta-1-like [Elephantulus edwardii].	24.23	421	250	14	40	434	263	640	2e-17	95.5
rs:WP_005427273	DNA topoisomerase I [[Ruminococcus] obeum].	24.83	439	271	13	34	454	212	609	2e-17	95.5
rs:WP_043104337	DNA topoisomerase I [Oleiagrimonas soli].	28.13	359	204	13	41	377	225	551	2e-17	95.5
rs:WP_045544581	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	2e-17	95.5
rs:WP_047540681	DNA topoisomerase I [Shewanella sp. ZOR0012].	25.78	450	271	17	10	446	232	631	2e-17	95.5
rs:WP_008336353	DNA topoisomerase I [Sulfurimonas gotlandica].	24.41	422	260	12	47	452	224	602	2e-17	95.5
rs:WP_046230703	DNA topoisomerase I [Paenibacillus algorifonticola].	25.92	436	254	18	45	457	226	615	2e-17	95.5
rs:XP_012139434	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Megachile rotundata].	24.89	466	279	16	18	452	1058	1483	2e-17	95.9
rs:XP_002834673	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Pongo abelii].	24.07	457	266	17	25	453	247	650	2e-17	95.5
rs:WP_023450209	DNA topoisomerase I [Asticcacaulis sp. AC402].	25.87	402	232	13	86	454	268	636	2e-17	95.5
rs:XP_004524694	PREDICTED: DNA topoisomerase 3-alpha [Ceratitis capitata].	25.33	454	257	18	37	451	278	688	2e-17	95.9
rs:WP_029176280	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	2e-17	95.5
tr:K1ZG32_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.37	455	256	15	22	452	239	638	2e-17	95.5
rs:WP_000024263	DNA topoisomerase I subunit omega [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	2e-17	95.5
rs:WP_000024264	topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	2e-17	95.5
rs:WP_000445594	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	236	593	2e-17	95.5
rs:WP_003651155	DNA topoisomerase I [Lactobacillus gasseri].	25.06	407	243	15	69	457	252	614	2e-17	95.5
rs:WP_003712550	DNA topoisomerase, partial [Lactobacillus oris].	31.91	188	115	6	56	237	54	234	2e-17	91.7
rs:NP_001253336	DNA topoisomerase 3-beta-1 [Macaca mulatta].	24.07	457	266	17	25	453	247	650	2e-17	95.5
rs:WP_044765802	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	2e-17	95.5
rs:XP_012789147	PREDICTED: DNA topoisomerase 3-alpha [Sorex araneus].	25.47	424	248	14	60	455	215	598	2e-17	95.5
rs:WP_019781670	DNA topoisomerase I [Streptococcus sobrinus].	23.89	427	249	14	50	452	254	628	2e-17	95.5
rs:XP_005907409	PREDICTED: DNA topoisomerase 3-beta-1 [Bos mutus].	24.04	441	255	16	40	453	263	650	2e-17	95.9
rs:WP_000179679	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	2e-17	95.5
rs:WP_011858247	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	176	559	2e-17	95.5
rs:XP_004843384	PREDICTED: DNA topoisomerase 3-beta-1 [Heterocephalus glaber].	24.04	441	255	16	40	453	263	650	2e-17	95.5
rs:XP_012857604	PREDICTED: DNA topoisomerase 3-alpha [Erythranthe guttatus].	25.37	469	275	15	18	451	247	675	2e-17	95.5
tr:R9RD65_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.96	366	220	10	26	377	209	537	2e-17	95.5
rs:WP_022295489	DNA topoisomerase [Firmicutes bacterium CAG:272].	25.66	417	250	14	60	454	237	615	2e-17	95.5
rs:WP_014565034	DNA topoisomerase I [Lactobacillus delbrueckii].	26.56	433	246	17	43	452	254	637	2e-17	95.5
rs:WP_041461236	DNA topoisomerase I [Fusobacterium nucleatum].	25.96	366	220	10	26	377	212	540	2e-17	95.5
rs:WP_024344084	DNA topoisomerase I [Streptococcus equinus].	24.29	424	251	14	50	452	252	626	2e-17	95.5
rs:XP_001510142	PREDICTED: DNA topoisomerase 3-alpha [Ornithorhynchus anatinus].	26.02	442	264	16	40	455	284	688	2e-17	95.9
rs:WP_004738038	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	2e-17	95.5
rs:XP_010025764	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Eucalyptus grandis].	25.11	466	271	15	24	452	248	672	2e-17	95.5
rs:WP_013774011	DNA topoisomerase I [Melissococcus plutonius].	24.34	419	253	15	61	457	239	615	2e-17	95.5
rs:WP_032044815	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	2e-17	95.5
rs:WP_031991904	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	2e-17	95.5
rs:WP_031973291	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	2e-17	95.5
rs:XP_005402335	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Chinchilla lanigera].	26.08	418	241	14	60	450	310	686	2e-17	95.5
rs:WP_044688674	DNA topoisomerase I [Streptococcus suis].	24.17	422	254	12	50	452	239	613	2e-17	95.5
rs:WP_024387763	DNA topoisomerase I [Streptococcus suis].	24.41	422	253	12	50	452	239	613	2e-17	95.5
rs:WP_048172579	DNA topoisomerase [Methanosarcina siciliae].	25.17	445	275	18	31	454	235	642	2e-17	95.5
tr:B0VL89_ACIBS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.17	427	254	19	40	452	266	649	2e-17	95.5
rs:WP_021668772	hypothetical protein, partial [Prevotella disiens].	32.75	171	111	3	152	321	20	187	2e-17	90.5
rs:WP_003647374	MULTISPECIES: DNA topoisomerase I [Lactobacillus].	25.12	406	242	15	70	457	253	614	2e-17	95.5
tr:A0A0E8T6Z5_STREE	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CRF97244.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRF97244.1};	24.21	409	237	14	66	452	254	611	2e-17	95.5
tr:V8CFY5_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.30	423	254	13	45	450	223	600	2e-17	95.5
rs:WP_034313673	DNA topoisomerase I [Bacillus simplex].	23.53	425	270	13	50	457	227	613	2e-17	95.5
rs:WP_046095456	DNA topoisomerase I [Corynebacterium ulcerans].	26.42	371	226	11	31	384	249	589	2e-17	95.5
rs:WP_029975064	DNA topoisomerase I [Corynebacterium ulcerans].	26.42	371	226	11	31	384	249	589	2e-17	95.5
rs:WP_000179647	DNA topoisomerase I, partial [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	2e-17	95.5
rs:WP_000308597	DNA topoisomerase I subunit omega, partial [Acinetobacter baumannii].	27.17	427	254	19	40	452	52	435	2e-17	95.1
rs:WP_006701213	DNA topoisomerase I [Facklamia ignava].	24.15	468	282	18	18	457	187	609	2e-17	95.5
gp:LN847353_1153	DNA topoisomerase I [Streptococcus pneumoniae]	24.21	409	237	14	66	452	254	611	2e-17	95.5
rs:WP_000179678	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	2e-17	95.5
rs:XP_011738033	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Macaca nemestrina].	24.07	457	266	17	25	453	247	650	2e-17	95.5
rs:WP_031764727	DNA topoisomerase I [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	2e-17	95.5
rs:WP_000024269	topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	2e-17	95.5
rs:WP_005226653	DNA topoisomerase I [Acinetobacter sp. NIPH 1847].	27.73	321	192	10	40	356	267	551	2e-17	95.5
rs:WP_033688907	DNA topoisomerase I [Streptococcus mitis].	24.21	409	237	14	66	452	236	593	2e-17	95.5
rs:XP_009355843	PREDICTED: DNA topoisomerase 3-alpha [Pyrus x bretschneideri].	25.06	439	269	12	39	451	269	673	2e-17	95.5
tr:A0A0E8T4C6_STREE	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CRF95442.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRF95442.1};	24.21	409	237	14	66	452	177	534	2e-17	95.1
rs:WP_035369177	DNA topoisomerase I [Acholeplasma hippikon].	25.83	422	237	15	57	456	227	594	2e-17	95.1
rs:WP_015158955	DNA topoisomerase I [Chamaesiphon minutus].	25.46	432	247	17	40	445	237	619	2e-17	95.5
rs:NP_001193635	DNA topoisomerase 3-beta-1 [Bos taurus].	24.04	441	255	16	40	453	263	650	2e-17	95.5
rs:WP_035725253	DNA topoisomerase I, partial [Fodinicurvata fenggangensis].	26.49	419	245	17	65	452	250	636	2e-17	95.5
rs:WP_000024262	DNA topoisomerase I subunit omega [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	2e-17	95.5
rs:WP_008043313	topoisomerase I [Reinekea blandensis].	25.40	433	264	14	36	452	253	642	2e-17	95.5
rs:WP_026403583	DNA topoisomerase I [Actinomadura rifamycini].	25.92	355	213	11	42	379	267	588	2e-17	95.5
rs:WP_021945740	DNA topoisomerase [Clostridium sp. CAG:967].	25.38	390	235	12	77	450	273	622	2e-17	95.5
rs:WP_030425043	DNA topoisomerase I, partial [Acinetobacter baumannii].	27.17	427	254	19	40	452	253	636	2e-17	95.5
rs:WP_044731729	DNA topoisomerase I [Geobacillus kaustophilus].	23.41	487	300	16	1	457	170	613	2e-17	95.1
rs:WP_000246895	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	2e-17	95.1
rs:WP_000179638	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	2e-17	95.1
rs:XP_004592097	PREDICTED: DNA topoisomerase 3-beta-1 [Ochotona princeps].	24.17	422	249	14	40	434	263	640	2e-17	95.5
rs:WP_032881097	DNA topoisomerase I [Pseudomonas sp. BRG-100].	24.59	427	278	14	46	459	230	625	2e-17	95.1
tr:A0A0F3GL30_9BACT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJU82537.1};	24.30	428	268	14	47	454	311	702	2e-17	95.5
rs:WP_003043663	DNA topoisomerase I subunit omega [Sphingopyxis sp. MC1].	26.67	420	251	13	54	452	235	618	2e-17	95.5
rs:WP_044758837	DNA topoisomerase I [Streptococcus suis].	24.12	427	248	13	50	452	239	613	2e-17	95.1
rs:WP_014255154	DNA topoisomerase I [[Clostridium] clariflavum].	24.76	424	266	13	50	457	229	615	2e-17	95.1
rs:WP_046693466	DNA topoisomerase I [Corynebacterium ulcerans].	26.42	371	226	11	31	384	249	589	2e-17	95.5
rs:WP_000445599	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	236	593	2e-17	95.1
tr:B2IPL8_STRPS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.21	409	237	14	66	452	260	617	2e-17	95.1
tr:H7PSL3_STREE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.21	409	237	14	66	452	150	507	2e-17	95.1
rs:WP_000179648	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	2e-17	95.1
tr:D6BDD4_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.96	366	220	10	26	377	212	540	2e-17	95.5
rs:WP_000024267	DNA topoisomerase I subunit omega [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	2e-17	95.5
rs:WP_033917814	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	2e-17	95.5
rs:WP_024404254	DNA topoisomerase I [Streptococcus suis].	23.65	427	251	12	50	452	239	614	2e-17	95.1
tr:A0A061I5V8_CRIGR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.81	441	256	16	40	453	194	581	2e-17	95.5
rs:XP_010380073	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Rhinopithecus roxellana].	24.07	457	266	17	25	453	111	514	2e-17	95.5
rs:WP_032839643	DNA topoisomerase I [Fusobacterium nucleatum].	25.96	366	220	10	26	377	212	540	2e-17	95.5
tr:A6BH91_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.00	427	261	14	48	457	231	619	2e-17	95.1
rs:XP_010380071	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Rhinopithecus roxellana].	24.07	457	266	17	25	453	247	650	2e-17	95.5
rs:WP_002350395	hypothetical protein, partial [Enterococcus faecium].	35.90	156	91	3	210	365	1	147	2e-17	92.4
tr:A0A0E8J504_STREE	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CRE70081.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRE70081.1};	24.21	409	237	14	66	452	254	611	2e-17	95.1
rs:XP_006065664	PREDICTED: DNA topoisomerase 3-beta-1 [Bubalus bubalis].	23.58	441	257	16	40	453	263	650	2e-17	95.5
tr:D4LWC7_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.71	437	274	12	34	454	212	609	2e-17	95.1
rs:WP_017482015	topoisomerase I [Acinetobacter calcoaceticus].	27.17	427	254	19	40	452	266	649	2e-17	95.5
rs:WP_015006903	MULTISPECIES: DNA topoisomerase I [Cycloclasticus].	26.52	396	234	15	77	452	263	621	2e-17	95.5
rs:WP_041171366	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	2e-17	95.1
rs:WP_034616985	DNA topoisomerase I [Desulfosporosinus sp. Tol-M].	25.12	426	263	14	48	454	225	613	2e-17	95.1
rs:WP_035374814	DNA topoisomerase I, partial [Acetobacter persici].	26.60	421	242	16	65	452	250	636	2e-17	95.5
rs:WP_000179649	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	2e-17	95.1
tr:A0A081QGC6_STRMT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.21	409	237	14	66	452	207	564	2e-17	95.1
rs:WP_022069750	DNA topoisomerase [Fusobacterium sp. CAG:649].	25.96	366	220	10	26	377	209	537	2e-17	95.5
rs:WP_031560908	DNA topoisomerase I, partial [Acinetobacter baumannii].	27.17	427	254	19	40	452	81	464	2e-17	95.1
rs:WP_000246896	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	2e-17	95.1
rs:WP_004957737	DNA topoisomerase I [Acinetobacter junii].	27.41	321	193	10	40	356	267	551	2e-17	95.5
rs:WP_005107951	DNA topoisomerase I [Acinetobacter lwoffii].	27.80	313	186	10	48	356	276	552	2e-17	95.5
rs:WP_010753926	DNA topoisomerase 1 [Enterococcus asini].	25.00	420	248	16	61	457	239	614	2e-17	95.1
rs:WP_034578557	DNA topoisomerase I, partial [Helicobacter canis].	25.30	423	254	13	45	450	223	600	2e-17	95.1
rs:WP_045106988	DNA topoisomerase I [Legionella hackeliae].	27.49	411	232	18	65	452	254	621	2e-17	95.1
rs:WP_025775433	hypothetical protein [Clostridium botulinum].	25.71	385	233	13	77	446	282	628	2e-17	95.5
tr:H7QP91_STREE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.21	409	237	14	66	452	207	564	2e-17	95.1
tr:U7TA88_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.96	366	220	10	26	377	209	537	2e-17	95.1
rs:WP_000179674	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	2e-17	95.1
rs:WP_022297042	DNA topoisomerase [Clostridium sp. CAG:465].	24.59	423	260	14	50	454	240	621	2e-17	95.1
rs:WP_041417181	DNA topoisomerase I [Shewanella sp. MR-7].	26.00	450	270	17	10	446	232	631	2e-17	95.5
rs:WP_001840255	DNA topoisomerase III, partial [Salmonella enterica].	45.35	86	47	0	36	121	251	336	2e-17	92.8
tr:A0A073KNM5_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.88	425	259	16	35	446	266	647	2e-17	95.5
rs:XP_511323	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Pan troglodytes].	25.66	417	244	13	60	450	310	686	2e-17	95.5
rs:WP_013910673	DNA topoisomerase I [Corynebacterium ulcerans].	26.42	371	226	11	31	384	249	589	2e-17	95.5
rs:XP_003702899	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Megachile rotundata].	25.21	468	275	17	18	452	710	1135	2e-17	95.5
rs:WP_027132250	DNA topoisomerase I [Fusobacterium necrophorum].	26.93	375	211	12	22	378	204	533	2e-17	95.1
rs:WP_034777177	DNA topoisomerase I [Exiguobacterium mexicanum].	24.94	453	272	16	35	454	197	614	2e-17	95.1
rs:WP_029599011	DNA topoisomerase I [Fusobacterium nucleatum].	25.96	366	220	10	26	377	212	540	2e-17	95.1
rs:XP_004680993	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Condylura cristata].	24.10	444	251	17	40	453	263	650	2e-17	95.5
sp:TOP3B_MOUSE	RecName: Full=DNA topoisomerase 3-beta-1; EC=5.99.1.2; AltName: Full=DNA topoisomerase III beta-1;	23.85	457	267	17	25	453	247	650	2e-17	95.5
rs:WP_009080346	DNA topoisomerase, partial [Peptostreptococcaceae bacterium AS15].	30.71	267	153	10	37	294	225	468	2e-17	94.4
rs:WP_000445596	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	236	593	2e-17	95.1
rs:WP_039690742	DNA topoisomerase I [Streptococcus equinus].	24.29	424	251	14	50	452	252	626	2e-17	95.1
rs:XP_005402336	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Chinchilla lanigera].	26.08	418	241	14	60	450	181	557	2e-17	95.5
rs:WP_005403630	topoisomerase I [Acinetobacter junii].	27.41	321	193	10	40	356	267	551	2e-17	95.5
rs:XP_009215138	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Papio anubis].	24.07	457	266	17	25	453	111	514	2e-17	95.1
rs:WP_024671025	DNA topoisomerase I [Pseudomonas syringae].	27.38	409	248	16	47	446	259	627	2e-17	95.5
rs:WP_000179652	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	2e-17	95.1
rs:XP_005281154	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Chrysemys picta bellii].	24.04	441	255	16	40	453	127	514	2e-17	95.1
rs:WP_043220818	DNA topoisomerase I [Pseudomonas balearica].	26.49	419	256	14	47	452	254	633	2e-17	95.5
rs:WP_038059400	hypothetical protein, partial [Thermodesulfovibrio islandicus].	25.69	432	259	13	41	452	233	622	2e-17	95.1
rs:WP_038621424	DNA topoisomerase I [Corynebacterium ulcerans].	26.42	371	226	11	31	384	249	589	2e-17	95.5
rs:XP_005567917	PREDICTED: DNA topoisomerase 3-beta-1 isoform X5 [Macaca fascicularis].	24.04	441	255	16	40	453	127	514	2e-17	95.1
rs:WP_024675102	DNA topoisomerase I [Pseudomonas syringae].	27.38	409	248	16	47	446	259	627	2e-17	95.5
rs:WP_004894564	DNA topoisomerase I [Lactobacillus johnsonii].	25.06	407	243	15	69	457	252	614	2e-17	95.1
rs:WP_014567529	DNA topoisomerase I [Lactobacillus johnsonii].	25.06	407	243	15	69	457	252	614	2e-17	95.1
rs:XP_010025763	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Eucalyptus grandis].	25.11	466	271	15	24	452	248	672	2e-17	95.5
tr:A0A0E8HMB2_STREE	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CRE51824.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRE51824.1};	24.21	409	237	14	66	452	254	611	2e-17	95.1
rs:WP_044791351	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	2e-17	95.1
rs:WP_000179673	DNA topoisomerase I [Streptococcus mitis].	24.21	409	237	14	66	452	254	611	2e-17	95.1
rs:WP_019491917	DNA topoisomerase I [Calothrix sp. PCC 7103].	25.24	420	259	14	40	443	242	622	2e-17	95.1
rs:WP_005250631	DNA topoisomerase I [Acinetobacter sp. CIP 102136].	27.80	313	186	10	48	356	276	552	2e-17	95.5
rs:WP_017361524	topoisomerase I [Pseudomonas mendocina].	25.49	408	257	13	47	446	258	626	2e-17	95.5
tr:F6Z0N0_ORNAN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.95	447	259	17	40	455	229	634	2e-17	95.5
rs:WP_004958844	DNA topoisomerase I [Acinetobacter junii].	27.41	321	193	10	40	356	267	551	2e-17	95.5
rs:WP_000179620	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	2e-17	95.1
rs:WP_021107261	type I topoisomease [Clostridium botulinum].	25.71	385	233	13	77	446	282	628	2e-17	95.1
rs:WP_024788245	MULTISPECIES: DNA topoisomerase I [Lebetimonas].	24.87	398	235	12	74	454	251	601	2e-17	95.1
rs:WP_004463162	DNA topoisomerase I [Ruminiclostridium thermocellum].	25.19	397	244	13	77	457	256	615	2e-17	95.1
rs:WP_000179639	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	2e-17	95.1
rs:WP_024299256	DNA topoisomerase I [Methylosarcina lacus].	26.62	447	245	18	41	452	225	623	2e-17	95.1
tr:D5HI49_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.41	426	267	12	45	454	238	624	2e-17	95.1
rs:WP_025677610	DNA topoisomerase I [Paenibacillus polymyxa].	25.67	413	247	15	65	457	242	614	2e-17	95.1
rs:XP_007623023	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Cricetulus griseus].	23.81	441	256	16	40	453	127	514	2e-17	95.1
rs:WP_028086981	DNA topoisomerase I [Dorea longicatena].	26.00	427	261	15	48	457	227	615	2e-17	95.1
rs:WP_000179630	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	2e-17	95.1
rs:YP_003446332	DNA topoisomerase I [Streptococcus mitis B6].	24.45	409	236	14	66	452	254	611	2e-17	95.1
rs:XP_010902673	PREDICTED: DNA topoisomerase 3-alpha, partial [Esox lucius].	25.67	448	262	15	39	455	302	709	2e-17	95.5
rs:WP_035416420	MULTISPECIES: DNA topoisomerase III, partial [Bacillus].	28.09	267	155	7	170	434	14	245	2e-17	92.8
rs:WP_011392540	DNA topoisomerase I [Moorella thermoacetica].	25.65	464	280	18	14	457	198	616	2e-17	95.1
rs:WP_031789231	DNA topoisomerase I, partial [Staphylococcus aureus].	24.94	429	253	18	47	452	224	606	2e-17	95.1
rs:WP_039210129	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	2e-17	95.1
rs:WP_037419529	DNA topoisomerase I [Shewanella xiamenensis].	25.88	425	259	16	35	446	250	631	2e-17	95.1
rs:WP_042890911	DNA topoisomerase I [Acinetobacter junii].	27.41	321	193	10	40	356	267	551	2e-17	95.1
rs:XP_003809826	PREDICTED: DNA topoisomerase 3-alpha [Pan paniscus].	25.66	417	244	13	60	450	310	686	2e-17	95.5
rs:WP_004897408	DNA topoisomerase I [Lactobacillus johnsonii].	25.06	407	243	15	69	457	252	614	2e-17	95.1
rs:WP_022415147	DNA topoisomerase [Dorea longicatena CAG:42].	26.00	427	261	14	48	457	227	615	2e-17	95.1
rs:XP_004896709	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Heterocephalus glaber].	25.62	445	262	16	40	455	289	693	2e-17	95.5
rs:WP_014525263	DNA topoisomerase I [Corynebacterium ulcerans].	26.42	371	226	11	31	384	249	589	2e-17	95.5
rs:WP_027191454	DNA topoisomerase I [Desulfovibrio putealis].	27.39	398	231	17	74	459	249	600	2e-17	95.1
rs:WP_008700964	DNA topoisomerase I [Fusobacterium nucleatum].	25.96	366	220	10	26	377	212	540	2e-17	95.1
rs:WP_039327136	hypothetical protein [Candidatus Saccharibacteria oral taxon TM7x].	27.65	293	170	7	45	334	221	474	2e-17	95.1
rs:WP_004916538	DNA topoisomerase I [Acinetobacter junii].	27.41	321	193	10	40	356	267	551	2e-17	95.1
rs:WP_019591561	DNA topoisomerase I [Thioalkalivibrio sp. ALE20].	28.57	329	182	8	36	350	233	522	2e-17	95.1
tr:H2NSY8_PONAB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.84	418	244	13	59	450	305	682	2e-17	95.1
tr:A0A0D6MI16_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.47	442	263	14	41	452	234	643	2e-17	95.1
rs:WP_002354369	hypothetical protein, partial [Enterococcus faecium].	35.22	159	94	3	207	365	1	150	2e-17	91.7
rs:XP_004607504	PREDICTED: DNA topoisomerase 3-beta-1 [Sorex araneus].	23.58	441	257	16	40	453	263	650	2e-17	95.1
rs:WP_038617458	DNA topoisomerase I [Corynebacterium ulcerans].	26.42	371	226	11	31	384	249	589	2e-17	95.5
rs:WP_022890767	DNA topoisomerase I [Agromyces italicus].	27.98	361	192	13	30	356	239	565	2e-17	95.1
rs:XP_009622049	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Nicotiana tomentosiformis].	24.46	466	285	15	18	452	248	677	2e-17	95.1
rs:WP_011630365	DNA topoisomerase I [Alkalilimnicola ehrlichii].	29.34	317	164	12	58	350	263	543	2e-17	95.1
rs:WP_042401695	hypothetical protein [Geomicrobium sp. JCM 19037].	31.14	228	135	8	232	454	3	213	2e-17	91.7
rs:XP_007973100	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Chlorocebus sabaeus].	24.07	457	266	17	25	453	111	514	2e-17	95.1
rs:WP_028035012	DNA topoisomerase I [Chelativorans sp. J32].	25.06	439	263	14	47	452	230	635	2e-17	95.1
rs:WP_002115027	MULTISPECIES: topoisomerase I [Acinetobacter calcoaceticus/baumannii complex].	27.17	427	254	19	40	452	266	649	2e-17	95.1
rs:WP_014208301	topoisomerase I [Acinetobacter calcoaceticus].	27.17	427	254	19	40	452	266	649	2e-17	95.1
rs:WP_029689028	DNA topoisomerase I [Thermoanaerobacter sp. A7A].	26.11	452	257	19	28	454	213	612	2e-17	95.1
rs:WP_041147928	DNA topoisomerase I [Sulfuricurvum sp. PC08-66].	24.94	421	258	14	47	452	225	602	2e-17	95.1
rs:WP_000179618	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	2e-17	95.1
rs:WP_016218473	DNA topoisomerase I [Dorea sp. 5-2].	24.00	425	272	11	48	457	226	614	2e-17	95.1
rs:XP_011842736	PREDICTED: DNA topoisomerase 3-beta-1 [Mandrillus leucophaeus].	24.07	457	266	17	25	453	247	650	2e-17	95.1
rs:WP_038088810	DNA topoisomerase I [Tumebacillus flagellatus].	25.11	474	275	21	18	457	188	615	2e-17	95.1
rs:WP_044736906	DNA topoisomerase I [Geobacillus kaustophilus].	23.41	487	300	16	1	457	170	613	2e-17	95.1
rs:WP_023599657	DNA topoisomerase I [Lactobacillus johnsonii].	25.06	407	243	15	69	457	252	614	2e-17	95.1
rs:WP_040418491	DNA topoisomerase I [Desulfonatronospira thiodismutans].	25.24	424	255	12	47	452	225	604	2e-17	95.1
rs:WP_022216093	DNA topoisomerase [Coprococcus sp. CAG:131].	24.41	426	267	12	45	454	249	635	2e-17	95.1
rs:WP_029943206	DNA topoisomerase I [Streptococcus suis].	25.12	422	250	13	50	452	239	613	2e-17	95.1
rs:WP_016743312	DNA topoisomerase I [Brevibacillus brevis].	24.77	432	258	15	49	457	226	613	2e-17	95.1
rs:WP_000179643	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	2e-17	95.1
rs:WP_005679476	DNA topoisomerase III [Bacteroides caccae].	24.24	330	219	8	61	385	263	566	2e-17	94.7
rs:WP_031491537	DNA topoisomerase I [Succinivibrio dextrinosolvens].	27.48	393	223	16	25	400	226	573	2e-17	95.1
rs:XP_006213913	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha [Vicugna pacos].	26.65	424	243	14	60	455	281	664	2e-17	95.1
rs:WP_016398196	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	2e-17	95.1
rs:WP_022470161	DNA topoisomerase III [Bacteroides thetaiotaomicron CAG:40].	30.34	234	147	8	60	289	17	238	2e-17	91.3
tr:A0A091NCS3_9PASS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.01	446	263	17	39	456	270	676	2e-17	95.1
rs:XP_003502892	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Cricetulus griseus].	23.81	441	256	16	40	453	263	650	2e-17	95.1
tr:A0A077HMZ8_9CORY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.96	335	192	12	30	354	245	543	2e-17	95.1
rs:WP_003462075	topoisomerase I [Pseudomonas pseudoalcaligenes].	25.49	408	257	13	47	446	257	625	2e-17	95.1
rs:WP_013714771	topoisomerase I [Pseudomonas mendocina].	25.49	408	257	13	47	446	258	626	2e-17	95.1
rs:XP_012294192	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Aotus nancymaae].	25.17	445	264	15	40	455	206	610	2e-17	95.1
rs:WP_021746945	DNA topoisomerase I [Leptotrichia wadei].	25.07	351	220	9	40	379	214	532	2e-17	95.1
rs:WP_034637643	DNA topoisomerase I [Desulfovibrio cuneatus].	26.21	435	254	18	34	451	242	626	2e-17	94.7
tr:J6XY22_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJY30884.1}; Flags: Fragment;	35.22	159	94	3	207	365	2	151	2e-17	91.3
rs:WP_000774786	DNA topoisomerase 1 [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	2e-17	95.1
rs:WP_033849501	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	2e-17	95.1
rs:WP_022698960	DNA topoisomerase I [Maricaulis sp. JL2009].	26.56	448	269	14	28	454	212	620	2e-17	95.1
rs:WP_024417943	DNA topoisomerase [Streptococcus suis].	27.76	335	198	12	60	385	264	563	2e-17	94.7
rs:WP_011609954	DNA topoisomerase I [Trichodesmium erythraeum].	25.70	393	240	11	30	398	235	599	2e-17	95.1
tr:A0A091TD74_PHALP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.66	438	258	15	25	434	224	617	2e-17	95.1
rs:WP_015199931	DNA topoisomerase I [Calothrix parietina].	25.12	422	257	15	40	443	241	621	2e-17	95.1
rs:XP_002159450	PREDICTED: DNA topoisomerase 3-alpha-like [Hydra vulgaris].	25.06	419	243	13	60	452	13	386	2e-17	95.1
rs:WP_046942317	DNA topoisomerase I [Haemophilus haemolyticus].	26.39	379	230	14	77	446	290	628	2e-17	95.1
rs:WP_011374691	DNA topoisomerase I [Lactobacillus sakei].	26.05	430	258	15	43	452	222	611	2e-17	94.7
gp:HE983624_851	DNA topoisomerase I [Streptococcus pneumoniae SPNA45]	24.21	409	237	14	66	452	202	559	2e-17	94.7
rs:WP_041835763	DNA topoisomerase I [Acidothermus cellulolyticus].	29.24	342	186	12	35	354	230	537	2e-17	95.1
rs:WP_003088291	DNA topoisomerase I [Streptococcus ratti].	23.76	442	264	14	34	452	228	619	2e-17	95.1
rs:WP_022571625	DNA topoisomerase I [Rhodobacteraceae bacterium HIMB11].	26.26	438	265	15	41	454	225	628	2e-17	95.1
rs:WP_016144255	DNA topoisomerase I [Acinetobacter pittii].	27.17	427	254	19	40	452	266	649	2e-17	95.1
rs:WP_032012359	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	2e-17	95.1
rs:WP_041973403	MULTISPECIES: DNA topoisomerase I [Streptococcus].	23.81	420	258	12	50	452	255	629	2e-17	95.1
rs:XP_012294193	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Aotus nancymaae].	25.17	445	264	15	40	455	289	693	2e-17	95.1
rs:WP_010226976	MULTISPECIES: topoisomerase I [Pseudomonas].	26.46	393	234	13	68	446	276	627	2e-17	95.1
rs:XP_004713017	PREDICTED: DNA topoisomerase 3-alpha [Echinops telfairi].	25.06	423	253	14	60	456	310	694	2e-17	95.1
rs:XP_005567913	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Macaca fascicularis].	24.04	441	255	16	40	453	263	650	2e-17	95.1
rs:WP_019589952	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	28.57	329	182	8	36	350	233	522	2e-17	95.1
rs:WP_003385908	DNA topoisomerase I [Brevibacillus borstelensis].	24.05	449	266	14	36	457	213	613	2e-17	94.7
rs:XP_005515230	PREDICTED: DNA topoisomerase 3-beta-1 [Columba livia].	24.94	441	253	16	25	434	247	640	2e-17	95.1
rs:XP_009436168	PREDICTED: DNA topoisomerase 3-beta-1 isoform X6 [Pan troglodytes].	24.82	419	236	15	61	453	129	494	2e-17	94.7
rs:XP_004481477	PREDICTED: DNA topoisomerase 3-alpha [Dasypus novemcinctus].	25.17	445	264	15	40	455	289	693	2e-17	95.1
rs:WP_047926641	DNA topoisomerase I [Neisseria gonorrhoeae].	23.92	485	265	13	41	454	225	676	2e-17	95.1
tr:A0A0B3AS91_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.76	420	220	17	74	453	382	745	2e-17	95.1
rs:WP_023938619	DNA topoisomerase I [Streptococcus pseudopneumoniae].	24.21	409	237	14	66	452	254	611	2e-17	94.7
rs:WP_021040976	Topoisomerase IA [Halonotius sp. J07HN4].	24.67	450	271	15	31	454	243	650	2e-17	95.1
rs:WP_031954307	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	2e-17	95.1
sp:TOP3A_ORYSJ	RecName: Full=DNA topoisomerase 3-alpha; EC=5.99.1.2;	25.00	440	269	15	39	452	270	674	2e-17	95.1
rs:WP_004326356	MULTISPECIES: DNA topoisomerase III [Bacteroidales].	24.17	393	242	12	21	394	220	575	2e-17	94.7
rs:WP_037587770	DNA topoisomerase I [Staphylococcus aureus].	25.81	399	230	16	76	452	253	607	2e-17	94.7
rs:XP_003865450	DNA topoisomerase III, putative [Leishmania donovani].	26.24	362	224	8	37	386	244	574	2e-17	95.1
rs:WP_003623892	DNA topoisomerase I [Lactobacillus delbrueckii].	26.33	433	247	17	43	452	254	637	2e-17	94.7
tr:A0A068FQU3_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:AID69676.1};	25.17	441	270	12	41	449	224	636	2e-17	95.1
rs:WP_003749245	DNA topoisomerase I [Neisseria mucosa].	24.32	481	263	12	43	454	228	676	3e-17	95.1
rs:WP_017385701	MULTISPECIES: topoisomerase I [Acinetobacter].	27.53	356	211	12	40	384	266	585	3e-17	95.1
rs:WP_005066066	MULTISPECIES: DNA topoisomerase I [Acinetobacter calcoaceticus/baumannii complex].	27.17	427	254	19	40	452	266	649	3e-17	95.1
rs:WP_009429851	DNA topoisomerase I [Oribacterium sp. oral taxon 108].	25.06	423	260	13	49	454	228	610	3e-17	94.7
rs:WP_003696216	DNA topoisomerase I [Neisseria gonorrhoeae].	23.92	485	265	13	41	454	225	676	3e-17	94.7
rs:WP_015462660	MULTISPECIES: DNA topoisomerase I [Xanthomonas].	25.93	428	261	14	46	459	229	614	3e-17	95.1
rs:XP_010635743	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Fukomys damarensis].	25.65	425	248	14	59	455	309	693	3e-17	95.1
rs:WP_024307541	DNA topoisomerase I [Pseudomonas sp. P818].	25.49	408	257	13	47	446	257	625	3e-17	95.1
rs:WP_024790332	DNA topoisomerase I [Lebetimonas sp. JH292].	25.06	399	233	13	74	454	251	601	3e-17	94.7
rs:WP_038613599	DNA topoisomerase I [Corynebacterium ureicelerivorans].	28.96	335	192	12	30	354	249	547	3e-17	95.1
rs:WP_007544534	DNA topoisomerase I [Listeria fleischmannii].	23.94	426	267	14	50	457	227	613	3e-17	94.7
tr:H0X7X3_OTOGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.39	449	266	15	36	455	285	693	3e-17	95.1
rs:WP_039257944	DNA topoisomerase I [Clostridium botulinum].	25.72	416	231	18	66	454	244	608	3e-17	94.7
rs:XP_007973097	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Chlorocebus sabaeus].	24.07	457	266	17	25	453	247	650	3e-17	95.1
rs:WP_040267900	DNA topoisomerase I [Xanthomonas citri].	25.93	428	261	14	46	459	229	614	3e-17	94.7
rs:WP_017398783	topoisomerase I [Acinetobacter pittii].	27.17	427	254	19	40	452	266	649	3e-17	95.1
rs:WP_032048758	DNA topoisomerase I [Acinetobacter baumannii].	27.53	356	211	12	40	384	266	585	3e-17	95.1
rs:XP_012294191	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Aotus nancymaae].	25.17	445	264	15	40	455	289	693	3e-17	95.1
rs:WP_002352807	DNA topoisomerase, partial [Enterococcus faecium].	30.47	233	150	5	57	286	268	491	3e-17	94.4
rs:WP_027837687	DNA topoisomerase I [Mastigocoleus testarum].	27.51	429	241	14	60	454	243	635	3e-17	95.1
rs:WP_027701667	DNA topoisomerase I [[Clostridium] mangenotii].	22.17	433	274	12	41	454	220	608	3e-17	94.7
rs:XP_009079665	PREDICTED: DNA topoisomerase 3-alpha [Acanthisitta chloris].	26.01	446	263	17	39	456	290	696	3e-17	95.1
rs:WP_024727734	DNA topoisomerase I [Clostridiales bacterium VE202-09].	23.65	427	269	9	48	457	227	613	3e-17	94.7
rs:WP_035419183	MULTISPECIES: DNA topoisomerase I [Bacillus].	23.94	426	263	15	47	452	224	608	3e-17	94.7
rs:WP_003613142	DNA topoisomerase I [Lactobacillus delbrueckii].	26.56	433	246	17	43	452	251	634	3e-17	94.7
rs:WP_042555596	DNA topoisomerase I [Pseudomonas fulva].	26.67	420	245	16	42	446	254	625	3e-17	95.1
rs:WP_033649945	DNA topoisomerase, partial [Enterococcus sp. GMD1E].	27.44	266	174	6	44	304	256	507	3e-17	94.4
rs:WP_004647399	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	27.80	313	186	10	48	356	276	552	3e-17	95.1
tr:W0JKP4_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.88	406	256	14	60	454	282	649	3e-17	94.7
tr:A0A0D2X5L3_CAPO3	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.09	322	192	11	39	352	474	757	3e-17	95.1
rs:WP_009533718	DNA topoisomerase I [Stomatobaculum longum].	26.46	427	257	13	49	457	230	617	3e-17	94.7
rs:WP_020308961	DNA topoisomerase I [Pseudomonas stutzeri].	26.54	407	249	14	60	459	234	597	3e-17	94.7
rs:WP_047005924	DNA topoisomerase I [Erythrobacter gangjinensis].	26.20	397	240	11	22	400	194	555	3e-17	94.7
rs:WP_034815084	DNA topoisomerase I [Exiguobacterium alkaliphilum].	25.00	416	262	12	56	454	232	614	3e-17	94.7
rs:WP_003615350	DNA topoisomerase I [Lactobacillus delbrueckii].	26.56	433	246	17	43	452	251	634	3e-17	94.7
tr:A0A087F896_9PSED	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.49	408	257	13	47	446	257	625	3e-17	95.1
rs:WP_046811441	DNA topoisomerase I [Acinetobacter pittii].	27.17	427	254	19	40	452	266	649	3e-17	95.1
rs:WP_021888524	DNA topoisomerase [Firmicutes bacterium CAG:110].	24.33	448	266	12	34	454	214	615	3e-17	94.7
rs:WP_021768179	DNA topoisomerase I [Leptotrichia sp. oral taxon 225].	27.22	338	191	10	60	379	232	532	3e-17	94.7
rs:XP_004640343	PREDICTED: DNA topoisomerase 3-alpha [Octodon degus].	25.51	439	258	15	40	450	293	690	3e-17	95.1
rs:XP_008167010	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Chrysemys picta bellii].	24.04	441	255	16	40	453	263	650	3e-17	94.7
rs:WP_000179636	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	3e-17	94.7
rs:WP_008852824	DNA topoisomerase I [Gluconobacter morbifer].	26.27	453	265	15	31	452	221	635	3e-17	95.1
tr:A0LWD4_ACIC1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	29.24	342	186	12	35	354	267	574	3e-17	95.1
rs:WP_047919959	DNA topoisomerase I [Neisseria gonorrhoeae].	23.92	485	265	13	41	454	225	676	3e-17	94.7
rs:WP_047924926	DNA topoisomerase I [Neisseria gonorrhoeae].	23.92	485	265	13	41	454	225	676	3e-17	94.7
rs:XP_011357358	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Pteropus vampyrus].	25.23	440	270	14	40	455	122	526	3e-17	94.7
rs:WP_045391379	DNA topoisomerase I [Falsirhodobacter sp. alg1].	25.81	430	262	12	47	454	229	623	3e-17	94.7
rs:WP_045874334	DNA topoisomerase I [Tolypothrix sp. PCC 7601].	24.36	427	264	14	40	446	241	628	3e-17	94.7
rs:WP_008820261	DNA topoisomerase, partial [Fusobacterium periodonticum].	25.96	366	220	10	26	377	212	540	3e-17	94.7
rs:XP_010635741	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Fukomys damarensis].	25.94	424	246	14	60	455	310	693	3e-17	95.1
rs:WP_024394027	DNA topoisomerase I [Streptococcus suis].	23.28	421	259	11	50	452	239	613	3e-17	94.7
tr:V1DHE5_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.78	450	271	17	10	446	248	647	3e-17	94.7
rs:WP_031807729	DNA topoisomerase 1 [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	3e-17	94.7
tr:D6SQD4_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.24	424	255	12	47	452	232	611	3e-17	94.7
rs:WP_017677648	MULTISPECIES: topoisomerase I [Pseudomonas].	26.21	412	249	15	47	446	258	626	3e-17	94.7
rs:WP_002215352	DNA topoisomerase I [Neisseria meningitidis].	24.22	483	261	14	43	454	228	676	3e-17	94.7
tr:A0A0D6G271_FUSNP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.90	368	214	12	26	377	209	537	3e-17	94.7
rs:WP_018287834	DNA topoisomerase I [zeta proteobacterium SCGC AB-133-G06].	25.23	440	267	16	41	459	219	617	3e-17	94.7
rs:WP_023060017	DNA topoisomerase I [Peptoniphilus sp. BV3AC2].	25.12	410	243	13	65	456	247	610	3e-17	94.7
rs:XP_006908498	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Pteropus alecto].	25.54	419	254	13	60	455	143	526	3e-17	94.7
tr:R3GZ90_ENTFL	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOJ98586.1};	25.32	316	191	7	133	445	5	278	3e-17	92.8
rs:XP_009430919	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Pan troglodytes].	25.66	417	244	13	60	450	215	591	3e-17	94.7
rs:XP_007973099	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Chlorocebus sabaeus].	24.07	457	266	17	25	453	186	589	3e-17	94.7
rs:WP_021288439	DNA topoisomerase I [Sulfurimonas sp. AST-10].	24.11	423	260	13	47	452	224	602	3e-17	94.7
rs:WP_029237111	DNA topoisomerase I [Streptococcus sobrinus].	23.99	446	258	15	34	452	237	628	3e-17	94.7
tr:E0PDM1_STREI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.81	420	258	12	50	452	291	665	3e-17	94.7
rs:WP_007089913	DNA topoisomerase I [Thalassospira xiamenensis].	25.30	423	247	15	65	454	248	634	3e-17	94.7
rs:XP_005997513	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Latimeria chalumnae].	25.35	434	265	14	40	450	283	680	3e-17	95.1
rs:WP_046193505	DNA topoisomerase I [Sphingomonas sp. SRS2].	27.15	442	250	15	34	452	225	617	3e-17	94.7
rs:WP_016399457	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	3e-17	94.7
tr:E9I3T1_DAPPU	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EFX61349.1}; Flags: Fragment;	31.58	209	122	5	198	396	1	198	3e-17	90.5
rs:WP_043041331	DNA topoisomerase I [Acinetobacter baumannii].	26.93	427	255	19	40	452	266	649	3e-17	94.7
rs:XP_005997514	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Latimeria chalumnae].	25.35	434	265	14	40	450	283	680	3e-17	94.7
rs:WP_046179161	DNA topoisomerase I [Domibacillus sp. PAMC 80007].	24.19	430	272	13	40	452	217	609	3e-17	94.7
rs:WP_015311654	DNA topoisomerase I [Thermoanaerobacterium thermosaccharolyticum].	26.28	411	231	16	69	454	247	610	3e-17	94.7
tr:H9EST7_MACMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.85	457	267	17	25	453	247	650	3e-17	94.7
tr:A0A010EZ36_ACIBA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.70	427	256	19	40	452	243	626	3e-17	94.7
rs:WP_021488552	topoisomerase I [Pseudomonas mendocina].	26.21	412	249	15	47	446	258	626	3e-17	94.7
rs:WP_029791739	DNA topoisomerase I [[Clostridium] mangenotii].	22.17	433	274	12	41	454	220	608	3e-17	94.7
rs:WP_005896639	DNA topoisomerase I [Fusobacterium nucleatum].	26.90	368	214	12	26	377	212	540	3e-17	94.7
rs:WP_024419473	DNA topoisomerase I [Streptococcus suis].	24.17	422	254	12	50	452	239	613	3e-17	94.7
rs:WP_032070408	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	3e-17	94.7
tr:A0A009FW92_ACIBA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.10	321	194	10	40	356	244	528	3e-17	94.7
rs:WP_006904981	DNA topoisomerase I [Thermaerobacter subterraneus].	25.57	442	268	16	36	454	213	616	3e-17	94.7
rs:XP_006908726	PREDICTED: DNA topoisomerase 3-beta-1 [Pteropus alecto].	23.85	457	267	17	25	453	247	650	3e-17	94.7
rs:WP_025774465	DNA topoisomerase I [Moorella thermoacetica].	25.65	464	280	18	14	457	197	615	3e-17	94.7
tr:H1PME7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.41	253	147	10	37	286	265	496	3e-17	94.0
rs:XP_008115565	PREDICTED: DNA topoisomerase 3-beta-1 [Anolis carolinensis].	24.26	441	254	16	40	453	263	650	3e-17	94.7
rs:WP_034561232	DNA topoisomerase I [Helicobacter macacae].	26.77	437	231	18	47	450	221	601	3e-17	94.7
rs:WP_031894812	DNA topoisomerase 1 [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	3e-17	94.7
rs:WP_034820674	DNA topoisomerase, partial [[Eubacterium] nodatum].	32.37	241	132	8	61	294	249	465	3e-17	94.0
rs:WP_009161146	DNA topoisomerase, partial [Prevotella saccharolytica].	25.34	292	192	7	30	311	28	303	3e-17	91.7
rs:WP_004294133	DNA topoisomerase III [Bacteroides eggerthii].	23.96	384	256	10	21	395	220	576	3e-17	94.4
rs:XP_007448453	PREDICTED: DNA topoisomerase 3-alpha [Lipotes vexillifer].	24.70	421	255	14	60	455	310	693	3e-17	94.7
rs:WP_021968589	DNA topoisomerase [Mycoplasma sp. CAG:956].	23.43	478	284	15	1	450	174	597	3e-17	94.4
rs:WP_009052420	DNA topoisomerase I [Thermoanaerobacter sp. X561].	26.11	452	257	19	28	454	213	612	3e-17	94.7
rs:XP_011357356	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Pteropus vampyrus].	25.23	440	270	14	40	455	289	693	3e-17	94.7
tr:J9J1U5_9SPIT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.78	353	208	12	40	378	377	689	3e-17	94.7
rs:WP_010346391	DNA topoisomerase I [Paenibacillus peoriae].	25.18	413	249	15	65	457	242	614	3e-17	94.7
rs:XP_012887054	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Dipodomys ordii].	23.81	441	256	16	40	453	166	553	3e-17	94.7
rs:WP_003679500	DNA topoisomerase I [Neisseria flavescens].	23.81	483	268	11	41	454	225	676	3e-17	94.7
rs:XP_011357357	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Pteropus vampyrus].	25.23	440	270	14	40	455	189	593	3e-17	94.7
tr:E5VTX7_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.53	425	272	11	48	457	227	613	3e-17	94.7
rs:WP_005061282	DNA topoisomerase I [Acinetobacter beijerinckii].	27.41	321	193	10	40	356	267	551	3e-17	94.7
tr:A0A0B8V5Z5_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	27.38	409	248	16	47	446	67	435	3e-17	94.4
rs:WP_048138449	DNA topoisomerase [Methanosarcina horonobensis].	24.56	452	263	17	34	454	238	642	3e-17	94.7
rs:WP_026619340	DNA topoisomerase I [Ensifer sp. WSM1721].	25.34	438	265	13	47	452	230	637	3e-17	94.7
rs:WP_002233406	DNA topoisomerase I [Neisseria meningitidis].	23.81	483	268	11	41	454	225	676	3e-17	94.7
rs:WP_031865838	DNA topoisomerase 1 [Staphylococcus aureus].	24.94	429	253	18	47	452	224	606	3e-17	94.4
rs:WP_040969433	DNA topoisomerase I [Mesorhizobium sp. ORS3324].	26.12	448	259	17	41	452	224	635	3e-17	94.7
rs:WP_022230020	DNA topoisomerase [Firmicutes bacterium CAG:41].	25.47	424	255	13	46	452	84	463	3e-17	94.4
rs:WP_031826017	DNA topoisomerase I [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	3e-17	94.4
rs:WP_008474129	DNA topoisomerase I [Lactobacillus gigeriorum].	25.49	408	243	15	68	457	254	618	3e-17	94.4
rs:WP_039631942	DNA topoisomerase I [Clostridium argentinense].	23.72	430	261	14	47	454	226	610	3e-17	94.4
rs:XP_006908497	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Pteropus alecto].	25.23	440	270	14	40	455	289	693	3e-17	94.7
tr:I6F9E1_SHIBO	SubName: Full=Topoisomerase DNA binding C4 zinc finger family protein {ECO:0000313|EMBL:EIQ52883.1};	37.06	143	81	4	308	450	1	134	3e-17	89.0
rs:WP_024397127	DNA topoisomerase I [Streptococcus suis].	24.17	422	254	12	50	452	239	613	3e-17	94.4
rs:WP_027115901	DNA topoisomerase I [Lachnospiraceae bacterium P6B14].	23.25	456	285	14	18	454	200	609	3e-17	94.4
rs:WP_035038494	DNA topoisomerase I [Devosia sp. DBB001].	26.93	427	262	14	47	452	230	627	3e-17	94.7
rs:WP_029936286	DNA topoisomerase I [Thiomicrospira pelophila].	29.89	261	145	7	77	334	253	478	3e-17	94.7
tr:D2U1Z5_9ENTR	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:CBA74913.1}; Flags: Fragment;	36.13	155	96	2	36	190	233	384	3e-17	92.8
rs:WP_019458040	MULTISPECIES: topoisomerase I [Acinetobacter].	26.93	427	255	19	40	452	266	649	3e-17	94.7
rs:WP_019570205	DNA topoisomerase I [Thioalkalivibrio sp. ALE11].	28.95	304	173	7	61	350	248	522	3e-17	94.7
rs:XP_005145100	PREDICTED: DNA topoisomerase 3-alpha [Melopsittacus undulatus].	25.39	445	267	15	39	456	290	696	3e-17	94.7
tr:H1DB08_9FUSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.70	343	198	10	51	378	17	324	3e-17	94.4
rs:XP_004342668	topoisomerase III [Capsaspora owczarzaki ATCC 30864].	26.01	323	193	11	38	352	473	757	3e-17	94.7
rs:WP_012974466	DNA topoisomerase I [Azospirillum lipoferum].	26.12	467	268	15	28	454	215	644	3e-17	94.7
rs:WP_027094806	DNA topoisomerase I [[Clostridium] viride].	26.46	446	259	16	34	454	214	615	3e-17	94.7
rs:WP_000774782	DNA topoisomerase I [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	3e-17	94.4
tr:A0A0D6DDF9_STAAU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	24.71	429	254	18	47	452	70	452	3e-17	94.0
rs:WP_032035863	DNA topoisomerase I [Acinetobacter baumannii].	27.17	427	254	19	40	452	266	649	3e-17	94.7
rs:WP_034682714	DNA topoisomerase I [Acinetobacter baumannii].	26.70	427	256	19	40	452	268	651	3e-17	94.7
rs:WP_009725216	DNA topoisomerase I [Methylophaga lonarensis].	27.14	409	245	15	61	452	248	620	3e-17	94.7
rs:WP_012154784	topoisomerase I [Shewanella pealeana].	27.79	349	199	11	57	388	271	583	3e-17	94.7
tr:A0A0E0GH85_ORYNI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.00	440	269	15	39	452	271	675	3e-17	94.7
rs:WP_036989641	DNA topoisomerase I [Pseudomonas bauzanensis].	26.00	450	265	15	7	446	235	626	3e-17	94.7
rs:WP_031790580	DNA topoisomerase I [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	3e-17	94.4
rs:WP_047928433	DNA topoisomerase I [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	3e-17	94.4
tr:A0A0E0GH83_ORYNI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.00	440	269	15	39	452	271	675	3e-17	94.7
rs:XP_006269380	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Alligator mississippiensis].	23.58	441	257	15	40	453	166	553	3e-17	94.7
rs:WP_011179396	DNA topoisomerase I [Bartonella quintana].	27.25	422	238	18	67	452	248	636	3e-17	94.7
rs:WP_009571103	DNA topoisomerase I [Celeribacter baekdonensis].	26.64	458	255	19	41	454	225	645	3e-17	94.7
rs:XP_006021588	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Alligator sinensis].	23.58	441	257	15	40	453	166	553	3e-17	94.4
tr:V8C8D1_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.77	437	231	18	47	450	271	651	3e-17	94.7
rs:WP_031882457	DNA topoisomerase 1 [Staphylococcus aureus].	24.94	429	253	18	47	452	224	606	3e-17	94.4
sp:TOP1_STAAM	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.71	429	254	18	47	452	224	606	3e-17	94.4
tr:G7PTT8_MACFA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.66	417	244	13	60	450	148	524	3e-17	94.7
tr:W8UYB5_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.71	429	254	18	47	452	226	608	3e-17	94.4
rs:WP_000179660	DNA topoisomerase I [Streptococcus mitis].	23.96	409	238	14	66	452	254	611	3e-17	94.4
rs:WP_035767149	DNA topoisomerase I [Butyrivibrio sp. NC2002].	24.41	422	262	12	50	454	234	615	3e-17	94.4
rs:XP_008008772	PREDICTED: DNA topoisomerase 3-alpha [Chlorocebus sabaeus].	25.66	417	244	13	60	450	310	686	3e-17	94.7
rs:WP_025732923	DNA topoisomerase I [Carnimonas nigrificans].	27.86	402	232	18	65	452	281	638	3e-17	94.7
tr:A0A090LVT9_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.71	429	254	18	47	452	226	608	3e-17	94.4
rs:WP_032582769	DNA topoisomerase III, partial [Campylobacter jejuni].	31.30	246	144	8	229	458	1	237	3e-17	91.7
rs:WP_018375537	DNA topoisomerase I [Streptococcus orisratti].	23.72	409	250	12	61	452	260	623	3e-17	94.4
rs:WP_011017773	DNA topoisomerase I [Streptococcus pyogenes].	23.22	422	258	14	50	452	250	624	3e-17	94.4
rs:WP_000179633	DNA topoisomerase I [Streptococcus pneumoniae].	24.69	409	235	14	66	452	254	611	3e-17	94.4
rs:XP_005997515	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Latimeria chalumnae].	25.35	434	265	14	40	450	283	680	3e-17	94.7
rs:WP_034554683	DNA topoisomerase I [Helicobacter apodemus].	24.59	423	253	13	47	450	224	599	3e-17	94.4
rs:XP_005183987	PREDICTED: DNA topoisomerase 3-beta [Musca domestica].	26.33	357	220	14	37	385	255	576	3e-17	94.7
rs:XP_012887052	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Dipodomys ordii].	23.81	441	256	16	40	453	263	650	4e-17	94.7
rs:WP_037426547	DNA topoisomerase I, partial [Shewanella sp. POL2].	25.78	450	271	17	10	446	84	483	4e-17	94.4
rs:WP_031895351	DNA topoisomerase 1 [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	4e-17	94.4
rs:WP_013370667	DNA topoisomerase I [Paenibacillus polymyxa].	25.42	413	248	15	65	457	242	614	4e-17	94.4
gpu:CP011212_801	topoisomerase I, DNA topoisomerase I protein [candidate division TM6 bacterium GW2011_GWF2_28_16]	27.49	411	237	15	59	452	257	623	4e-17	94.4
rs:WP_033867932	DNA topoisomerase I [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	4e-17	94.4
rs:WP_034455256	DNA topoisomerase I [Bartonella quintana].	27.25	422	238	18	67	452	248	636	4e-17	94.7
rs:WP_024983845	DNA topoisomerase I [Brevibacillus borstelensis].	23.83	449	267	14	36	457	213	613	4e-17	94.4
rs:WP_047172476	DNA topoisomerase I [Staphylococcus xylosus].	25.06	395	234	14	77	452	254	605	4e-17	94.4
rs:WP_000774779	DNA topoisomerase I [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	4e-17	94.4
rs:WP_005079182	MULTISPECIES: DNA topoisomerase I [Acinetobacter calcoaceticus/baumannii complex].	27.17	427	254	19	40	452	266	649	4e-17	94.7
rs:WP_024392292	DNA topoisomerase I [Streptococcus suis].	24.17	422	254	12	50	452	239	613	4e-17	94.4
rs:WP_016222617	DNA topoisomerase I [Lachnospiraceae bacterium 3-2].	25.96	416	254	13	58	457	237	614	4e-17	94.4
rs:WP_024094293	DNA topoisomerase 1 [Paenibacillus larvae].	25.81	434	252	15	51	457	224	614	4e-17	94.4
rs:WP_000774776	DNA topoisomerase 1 [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	4e-17	94.4
rs:WP_013175125	DNA topoisomerase I [Syntrophothermus lipocalidus].	25.94	424	256	13	47	452	221	604	4e-17	94.4
rs:WP_039978511	DNA topoisomerase I [Shewanella decolorationis].	25.78	450	271	17	10	446	232	631	4e-17	94.7
rs:WP_005232311	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	27.10	321	194	10	40	356	268	552	4e-17	94.7
rs:WP_011284793	DNA topoisomerase I [Streptococcus pyogenes].	23.22	422	258	14	50	452	250	624	4e-17	94.4
rs:WP_034291938	DNA topoisomerase I [Alysiella crassa].	25.35	430	265	12	41	452	227	618	4e-17	94.4
rs:WP_012658424	DNA topoisomerase I [Streptococcus uberis].	23.83	428	248	15	50	452	250	624	4e-17	94.4
rs:WP_037592149	MULTISPECIES: DNA topoisomerase I [Streptococcus].	23.83	428	248	15	50	452	250	624	4e-17	94.4
rs:WP_031765830	DNA topoisomerase 1 [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	4e-17	94.4
rs:WP_031838416	DNA topoisomerase I [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	4e-17	94.4
tr:A0A077KUW3_ACIGI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.40	356	215	11	40	384	268	587	4e-17	94.7
tr:K1ZI81_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.94	425	264	12	47	452	227	615	4e-17	94.4
rs:XP_005583130	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Macaca fascicularis].	25.66	417	244	13	60	450	310	686	4e-17	94.7
rs:WP_022506394	DNA topoisomerase [Eubacterium sp. CAG:581].	25.22	460	251	17	47	449	226	649	4e-17	94.4
rs:WP_031929655	DNA topoisomerase 1 [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	4e-17	94.4
rs:WP_004698880	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	26.93	427	255	19	40	452	266	649	4e-17	94.4
rs:WP_034169866	DNA topoisomerase I [Acinetobacter sp. YZS-X1-1].	27.10	321	194	10	40	356	268	552	4e-17	94.4
rs:WP_022302396	DNA topoisomerase III [Bacteroides faecis CAG:32].	24.29	387	249	12	21	394	220	575	4e-17	94.0
rs:WP_047235284	DNA topoisomerase I [Streptococcus pyogenes].	23.22	422	258	14	50	452	250	624	4e-17	94.4
rs:XP_010281265	PREDICTED: DNA topoisomerase 3-beta-1 [Phaethon lepturus].	24.66	438	258	15	25	434	271	664	4e-17	94.4
rs:WP_000774791	DNA topoisomerase I [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	4e-17	94.4
rs:WP_039969953	DNA topoisomerase I [Bacteroides fluxus].	24.49	392	259	11	5	387	204	567	4e-17	94.0
rs:WP_044971912	DNA topoisomerase I [Clostridiaceae bacterium MS3].	25.06	399	241	12	74	454	255	613	4e-17	94.4
rs:WP_028772459	DNA topoisomerase I [Shewanella waksmanii].	28.93	356	204	14	42	384	257	576	4e-17	94.4
rs:WP_017400709	topoisomerase I [Acinetobacter radioresistens].	26.70	427	256	19	40	452	268	651	4e-17	94.4
tr:A0A096P334_PAPAN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.66	417	244	13	60	450	310	686	4e-17	94.7
tr:H9Z0Q7_MACMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.66	417	244	13	60	450	310	686	4e-17	94.7
rs:WP_007430014	DNA topoisomerase I [Paenibacillus sp. Aloe-11].	25.18	413	249	15	65	457	242	614	4e-17	94.4
rs:WP_023484649	DNA topoisomerase I-like protein [Paenibacillus larvae].	25.81	434	252	15	51	457	224	614	4e-17	94.4
gp:CP010941_1149	DNA topoisomerase I [Staphylococcus aureus]	24.71	429	254	18	47	452	224	606	4e-17	94.4
rs:WP_013045489	DNA topoisomerase I [Candidatus Puniceispirillum marinum].	27.71	415	236	16	70	452	253	635	4e-17	94.4
rs:WP_005023286	MULTISPECIES: topoisomerase I [Acinetobacter].	26.70	427	256	19	40	452	268	651	4e-17	94.4
rs:WP_010630966	DNA topoisomerase I [Sporolactobacillus vineae].	25.71	420	250	17	61	457	237	617	4e-17	94.4
rs:XP_012520437	PREDICTED: DNA topoisomerase 3-alpha [Propithecus coquereli].	25.94	424	246	15	60	455	310	693	4e-17	94.7
rs:WP_039693667	DNA topoisomerase I [Streptococcus gallolyticus].	23.81	420	258	12	50	452	253	627	4e-17	94.4
rs:WP_000774781	DNA topoisomerase I [Staphylococcus aureus].	24.94	429	253	18	47	452	224	606	4e-17	94.4
rs:WP_005352530	hypothetical protein [[Eubacterium] siraeum].	23.35	394	257	13	69	446	144	508	4e-17	94.4
rs:WP_002984618	DNA topoisomerase I [Streptococcus pyogenes].	23.22	422	258	14	50	452	250	624	4e-17	94.4
rs:WP_011528644	DNA topoisomerase I [Streptococcus pyogenes].	23.22	422	258	14	50	452	250	624	4e-17	94.4
tr:A8K4N2_HUMAN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.29	457	265	17	25	453	247	650	4e-17	94.4
rs:WP_042362837	DNA topoisomerase I [Staphylococcus xylosus].	25.32	395	233	14	77	452	254	605	4e-17	94.4
rs:WP_047917934	DNA topoisomerase I [Neisseria gonorrhoeae].	23.92	485	265	13	41	454	225	676	4e-17	94.4
tr:J9GHA6_9ZZZZ	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EJW98799.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EJW98799.1};	36.67	150	93	1	255	402	9	158	4e-17	91.3
rs:WP_012300871	hypothetical protein [Clostridium botulinum].	25.71	385	233	13	77	446	282	628	4e-17	94.4
rs:WP_013625429	DNA topoisomerase I [Syntrophobotulus glycolicus].	24.71	433	264	10	47	457	224	616	4e-17	94.4
rs:WP_038696754	DNA topoisomerase I [Paenibacillus stellifer].	24.65	434	255	17	50	457	227	614	4e-17	94.4
tr:H9EWR7_MACMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.66	417	244	13	60	450	310	686	4e-17	94.7
tr:A0A009N8A3_ACIBA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.70	427	256	19	40	452	243	626	4e-17	94.4
rs:WP_031472082	DNA topoisomerase I [Eubacterium desmolans].	28.41	440	258	18	36	454	211	614	4e-17	94.4
rs:WP_017626847	DNA topoisomerase I [Nocardiopsis chromatogenes].	26.84	354	211	11	42	379	276	597	4e-17	94.4
rs:WP_003714143	DNA topoisomerase I [Neisseria lactamica].	23.92	485	265	13	41	454	225	676	4e-17	94.4
rs:WP_040931294	DNA topoisomerase I, partial [Paenibacillus larvae].	25.81	434	252	15	51	457	209	599	4e-17	94.4
rs:WP_041497609	DNA topoisomerase I, partial [Staphylococcus aureus].	24.71	429	254	18	47	452	184	566	4e-17	94.4
rs:WP_005968475	DNA topoisomerase I [Fusobacterium periodonticum].	26.59	331	196	9	61	377	240	537	4e-17	94.4
tr:F3PYL3_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.49	392	259	11	5	387	213	576	4e-17	94.0
rs:WP_034428678	DNA topoisomerase I [Acinetobacter radioresistens].	26.70	427	256	19	40	452	268	651	4e-17	94.4
rs:XP_004684597	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Condylura cristata].	25.17	445	264	15	40	455	289	693	4e-17	94.4
rs:XP_004684596	PREDICTED: DNA topoisomerase 3-alpha [Condylura cristata].	25.47	424	248	14	60	455	310	693	4e-17	94.4
rs:WP_004876697	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	27.41	321	193	10	40	356	267	551	4e-17	94.4
rs:WP_036573083	DNA topoisomerase I [Oceanobacillus picturae].	25.12	418	251	14	61	457	238	614	4e-17	94.4
rs:WP_047338534	DNA topoisomerase I [Enterococcus cecorum].	24.38	447	272	19	34	457	211	614	4e-17	94.4
rs:WP_013643118	DNA topoisomerase I [Streptococcus gallolyticus].	23.81	420	258	12	50	452	253	627	4e-17	94.4
rs:WP_006770208	DNA topoisomerase I [Corynebacterium efficiens].	26.18	340	204	9	31	354	253	561	4e-17	94.4
rs:WP_009880713	DNA topoisomerase I [Streptococcus pyogenes].	23.22	422	258	14	50	452	250	624	4e-17	94.4
rs:XP_005583131	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Macaca fascicularis].	25.66	417	244	13	60	450	262	638	4e-17	94.4
rs:WP_003690118	DNA topoisomerase I [Neisseria gonorrhoeae].	23.92	485	265	13	41	454	225	676	4e-17	94.4
rs:XP_008120113	PREDICTED: DNA topoisomerase 3-alpha isoform X4 [Anolis carolinensis].	25.06	423	251	17	60	455	257	640	4e-17	94.4
rs:WP_009157827	DNA topoisomerase I [Thalassobium sp. R2A62].	26.77	437	260	18	41	452	225	626	4e-17	94.4
rs:WP_039277129	DNA topoisomerase I [Paenibacillus polymyxa].	25.42	413	248	15	65	457	242	614	4e-17	94.4
rs:WP_031788381	DNA topoisomerase I [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	4e-17	94.4
rs:WP_044433901	DNA topoisomerase I [Acinetobacter ursingii].	26.53	426	258	18	40	452	269	652	4e-17	94.4
gp:CP010526_1201	DNA topoisomerase I [Staphylococcus aureus subsp. aureus ST772-MRSA-V]	24.71	429	254	18	47	452	226	608	4e-17	94.4
rs:WP_022181766	DNA topoisomerase [Firmicutes bacterium CAG:137].	25.92	409	246	14	65	454	2	372	4e-17	94.0
rs:WP_011054502	DNA topoisomerase I [Streptococcus pyogenes].	23.22	422	258	14	50	452	250	624	4e-17	94.4
rs:WP_047412855	DNA topoisomerase I [Caulobacter sp. OV484].	26.70	427	238	15	61	452	243	629	4e-17	94.4
rs:WP_030126679	DNA topoisomerase I [Streptococcus pyogenes].	23.22	422	258	14	50	452	250	624	4e-17	94.4
rs:WP_011344688	DNA topoisomerase I [Carboxydothermus hydrogenoformans].	24.18	455	261	13	47	449	223	645	4e-17	94.4
rs:XP_010985627	PREDICTED: DNA topoisomerase 3-beta-1, partial [Camelus dromedarius].	23.70	422	251	14	40	434	263	640	4e-17	94.4
rs:WP_003464782	DNA topoisomerase III [Clostridium perfringens].	27.10	369	220	16	98	452	306	639	4e-17	94.4
rs:WP_022789185	DNA topoisomerase I [[Streptococcus] pleomorphus].	26.44	435	253	16	40	452	219	608	4e-17	94.4
rs:XP_006269379	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Alligator mississippiensis].	23.58	441	257	15	40	453	263	650	4e-17	94.4
rs:WP_003694350	DNA topoisomerase I [Neisseria gonorrhoeae].	23.92	485	265	13	41	454	225	676	4e-17	94.4
rs:WP_003690297	DNA topoisomerase I [Neisseria gonorrhoeae].	23.92	485	265	13	41	454	225	676	4e-17	94.4
rs:WP_040202472	DNA topoisomerase III, partial [Klebsiella pneumoniae].	30.15	199	112	6	277	459	9	196	4e-17	91.3
rs:WP_011791321	DNA topoisomerase I [Desulfovibrio vulgaris].	24.77	428	263	12	41	452	230	614	4e-17	94.4
tr:A0A0E1X6A0_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.71	429	254	18	47	452	226	608	4e-17	94.4
rs:WP_025850763	DNA topoisomerase I [Paenibacillus ehimensis].	24.42	471	285	15	18	457	187	617	4e-17	94.4
rs:XP_010953763	PREDICTED: DNA topoisomerase 3-beta-1 [Camelus bactrianus].	23.70	422	251	14	40	434	263	640	4e-17	94.4
rs:XP_006213369	PREDICTED: DNA topoisomerase 3-beta-1 [Vicugna pacos].	23.70	422	251	14	40	434	263	640	4e-17	94.4
rs:WP_029751772	DNA topoisomerase I [Streptococcus suis].	24.17	422	254	12	50	452	239	613	4e-17	94.4
rs:WP_004802538	DNA topoisomerase I [Acinetobacter sp. CIP 56.2].	26.76	426	257	18	40	452	267	650	4e-17	94.4
rs:WP_005016677	MULTISPECIES: topoisomerase I [Acinetobacter].	26.70	427	256	19	40	452	268	651	4e-17	94.4
tr:A0A0E1XFF3_STRGY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.81	420	258	12	50	452	291	665	4e-17	94.4
rs:WP_000618852	hypothetical protein, partial [Staphylococcus aureus].	24.94	429	253	18	47	452	6	388	4e-17	93.6
rs:WP_004611389	DNA topoisomerase I [Tyzzerella nexilis].	24.18	426	269	11	48	457	227	614	4e-17	94.0
rs:WP_044811425	DNA topoisomerase I [Streptococcus pneumoniae].	24.69	409	235	14	66	452	254	611	4e-17	94.0
rs:XP_005233334	PREDICTED: DNA topoisomerase 3-beta-1 [Falco peregrinus].	24.73	457	263	17	25	453	247	650	4e-17	94.4
rs:XP_004684598	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Condylura cristata].	25.47	424	248	14	60	455	215	598	4e-17	94.4
rs:WP_037282401	DNA topoisomerase I [Saccharibacillus sacchari].	24.25	433	260	16	50	458	227	615	4e-17	94.0
rs:WP_008122907	DNA topoisomerase I [Phyllobacterium sp. YR531].	26.54	407	237	13	77	452	260	635	4e-17	94.4
rs:WP_023605114	DNA topoisomerase I [Streptococcus pyogenes].	23.79	454	279	16	19	452	218	624	4e-17	94.4
rs:WP_017569354	DNA topoisomerase I [Nocardiopsis halotolerans].	26.89	357	219	10	36	379	271	598	4e-17	94.4
rs:WP_016360252	MULTISPECIES: DNA topoisomerase I [Clostridiales].	25.06	399	241	12	74	454	255	613	4e-17	94.0
rs:WP_012301722	DNA topoisomerase I [Candidatus Desulforudis audaxviator].	25.72	416	246	16	61	454	239	613	4e-17	94.4
rs:WP_006586737	DNA topoisomerase I [Lactobacillus jensenii].	24.77	428	260	14	43	452	224	607	4e-17	94.0
rs:WP_007478962	MULTISPECIES: topoisomerase I [Acinetobacter].	27.41	321	193	10	40	356	267	551	4e-17	94.4
rs:WP_007739277	DNA topoisomerase I [Halococcus thailandensis].	25.59	379	234	12	86	454	292	632	4e-17	94.4
rs:WP_000179646	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	254	611	4e-17	94.0
gp:CP010943_1100	DNA topoisomerase I [Staphylococcus aureus]	24.88	426	251	18	50	452	227	606	4e-17	94.0
rs:WP_034622365	DNA topoisomerase I, partial [Desulfovermiculus halophilus].	23.70	422	264	11	47	452	225	604	4e-17	94.4
rs:WP_011316928	DNA topoisomerase I [Anabaena variabilis].	26.53	343	204	10	77	402	285	596	4e-17	94.4
rs:WP_013523392	MULTISPECIES: DNA topoisomerase I [Geobacillus].	23.61	487	299	16	1	457	170	613	4e-17	94.0
rs:WP_013145765	DNA topoisomerase I [Geobacillus sp. C56-T3].	23.61	487	299	16	1	457	170	613	4e-17	94.0
rs:WP_023634013	DNA topoisomerase I [Geobacillus sp. MAS1].	23.61	487	299	16	1	457	170	613	4e-17	94.0
rs:WP_038094767	hypothetical protein, partial [Tumebacillus flagellatus].	25.25	408	251	14	66	454	244	616	4e-17	94.0
rs:WP_003517938	DNA topoisomerase I [Ruminiclostridium thermocellum].	25.19	397	244	13	77	457	256	615	4e-17	94.0
rs:WP_039409382	DNA topoisomerase I [Morococcus cerebrosus].	23.92	485	265	13	41	454	225	676	4e-17	94.4
rs:WP_047949553	DNA topoisomerase I [Neisseria gonorrhoeae].	23.92	485	265	13	41	454	225	676	4e-17	94.4
rs:WP_025335382	DNA topoisomerase I [Paenibacillus sabinae].	24.88	434	254	16	50	457	227	614	4e-17	94.0
rs:XP_009472958	PREDICTED: DNA topoisomerase 3-beta-1 [Nipponia nippon].	24.66	438	258	15	25	434	240	633	4e-17	94.4
tr:A0A0C6FVI5_STRPY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.22	422	258	14	50	452	250	624	4e-17	94.0
rs:XP_003228350	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Anolis carolinensis].	25.06	423	251	17	60	455	283	666	4e-17	94.4
rs:WP_047235810	DNA topoisomerase I [Streptococcus pyogenes].	23.22	422	258	13	50	452	250	624	4e-17	94.0
rs:WP_001719610	DNA topoisomerase III, partial [Salmonella enterica].	35.77	137	84	1	37	173	245	377	4e-17	92.4
rs:WP_032095784	MULTISPECIES: DNA topoisomerase I [Alteromonas].	27.43	412	245	16	47	446	261	630	4e-17	94.4
rs:WP_018670812	DNA topoisomerase I [Brevibacillus laterosporus].	25.16	473	275	16	18	457	187	613	4e-17	94.0
rs:XP_009966981	PREDICTED: DNA topoisomerase 3-alpha, partial [Tyto alba].	26.23	446	263	16	40	456	235	643	4e-17	94.4
rs:WP_010976540	DNA topoisomerase I [Streptococcus pneumoniae].	24.21	409	237	14	66	452	260	617	4e-17	94.0
tr:A0A094Q164_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KGA15784.1};	26.91	327	197	9	41	354	251	548	4e-17	94.4
rs:WP_026734142	DNA topoisomerase I [Fischerella sp. PCC 9605].	26.07	349	217	9	41	379	255	572	4e-17	94.4
rs:WP_047917299	DNA topoisomerase I [Neisseria gonorrhoeae].	23.92	485	265	13	41	454	225	676	4e-17	94.4
rs:WP_033916179	DNA topoisomerase I [Campylobacter sputorum].	25.35	426	250	16	45	450	222	599	4e-17	94.0
rs:WP_023499727	Topoisomerase IA [uncultured archaeon A07HB70].	25.06	387	241	12	81	454	285	635	4e-17	94.4
rs:WP_011161948	DNA topoisomerase I [Lactobacillus johnsonii].	24.07	432	267	14	43	457	227	614	4e-17	94.0
rs:WP_048170755	DNA topoisomerase [Methanosarcina sp. 2.H.A.1B.4].	25.22	452	260	17	34	454	238	642	4e-17	94.4
tr:W2BXL6_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.37	241	132	8	61	294	249	465	4e-17	94.0
rs:WP_041370740	hypothetical protein, partial [Methylovorus glucosotrophus].	22.86	398	255	14	60	449	227	580	4e-17	94.0
rs:XP_010130050	PREDICTED: DNA topoisomerase 3-beta-1 [Buceros rhinoceros silvestris].	24.66	438	258	15	25	434	247	640	4e-17	94.4
rs:WP_047951377	DNA topoisomerase I [Neisseria gonorrhoeae].	23.92	485	265	13	41	454	225	676	4e-17	94.4
rs:WP_000774792	DNA topoisomerase I [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	5e-17	94.0
rs:WP_040373193	DNA topoisomerase I [Bacillus psychrosaccharolyticus].	23.06	425	263	15	50	452	227	609	5e-17	94.0
rs:WP_046140197	MULTISPECIES: DNA topoisomerase I [Devosia].	26.92	416	250	16	60	452	243	627	5e-17	94.4
tr:H5SLA0_9CHLR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.61	447	274	14	36	457	235	643	5e-17	94.0
rs:XP_003862289	DNA topoisomerase III, putative [Leishmania donovani].	23.98	417	259	12	39	434	252	631	5e-17	94.4
rs:WP_013191215	DNA topoisomerase I [Trichormus azollae].	26.32	342	204	10	77	401	285	595	5e-17	94.4
rs:WP_026566452	DNA topoisomerase I [Bacillus sp. UNC41MFS5].	25.00	420	248	17	61	457	239	614	5e-17	94.0
rs:NP_269314	putative DNA topoisomerase I [Streptococcus pyogenes M1 GAS].	23.22	422	258	14	50	452	250	624	5e-17	94.0
rs:WP_008314273	DNA topoisomerase I [Leptolyngbya sp. PCC 6406].	27.30	370	221	12	25	379	230	566	5e-17	94.4
rs:WP_034811450	DNA topoisomerase I [[Eubacterium] sulci].	24.38	484	291	16	2	457	165	601	5e-17	94.0
rs:WP_029764261	DNA topoisomerase I [Gemmatimonadetes bacterium JGI 0000112-M07].	25.06	447	268	16	35	457	211	614	5e-17	94.0
rs:XP_008120111	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Anolis carolinensis].	25.06	423	251	17	60	455	314	697	5e-17	94.4
rs:WP_045243859	DNA topoisomerase I [Paenibacillus polymyxa].	25.42	413	248	15	65	457	242	614	5e-17	94.0
rs:WP_000445597	DNA topoisomerase I [Streptococcus pneumoniae].	23.96	409	238	14	66	452	236	593	5e-17	94.0
tr:T1DLK2_CROHD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.60	435	260	15	40	453	263	650	5e-17	94.4
rs:XP_006177120	PREDICTED: DNA topoisomerase 3-beta-1 [Camelus ferus].	23.70	422	251	14	40	434	263	640	5e-17	94.4
rs:WP_038994330	DNA topoisomerase I [Pseudomonas putida].	26.46	393	234	13	68	446	276	627	5e-17	94.4
rs:WP_012846247	DNA topoisomerase I [Lactobacillus johnsonii].	24.57	407	245	14	69	457	252	614	5e-17	94.0
rs:XP_008564436	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Galeopterus variegatus].	25.24	424	249	14	60	455	123	506	5e-17	94.0
tr:A0A0C1GX80_9NEIS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.92	485	265	13	41	454	247	698	5e-17	94.0
rs:XP_008564435	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Galeopterus variegatus].	24.94	445	265	15	40	455	289	693	5e-17	94.4
tr:A0A0B8REZ8_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.03	444	255	16	41	452	225	631	5e-17	94.4
tr:K1U396_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC76693.1}; Flags: Fragment;	35.75	179	108	5	60	237	176	348	5e-17	92.0
rs:WP_031952082	DNA topoisomerase I [Acinetobacter baumannii].	26.93	427	255	19	40	452	266	649	5e-17	94.4
rs:WP_000774777	DNA topoisomerase 1 [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	5e-17	94.0
rs:WP_010393696	DNA topoisomerase I [Paracoccus sp. TRP].	27.18	401	235	15	77	454	259	625	5e-17	94.0
rs:WP_014705479	DNA topoisomerase I [Methylophaga nitratireducenticrescens].	27.57	428	248	17	46	452	234	620	5e-17	94.0
rs:WP_034841315	DNA topoisomerase I [Endozoicomonas numazuensis].	25.06	395	242	14	63	446	281	632	5e-17	94.4
rs:WP_028512772	DNA topoisomerase I [Ruminococcaceae bacterium AE2021].	25.71	455	290	10	15	452	197	620	5e-17	94.0
rs:WP_007618918	DNA topoisomerase I [Gordonia soli].	26.89	357	212	11	41	379	270	595	5e-17	94.4
rs:WP_038293838	DNA topoisomerase I, partial [alpha proteobacterium SCGC AB-629-F11].	28.57	420	232	19	65	452	249	632	5e-17	94.0
tr:A0A091UPR8_NIPNI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.66	438	258	15	25	434	224	617	5e-17	94.0
rs:XP_012603375	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Microcebus murinus].	25.24	424	249	14	60	455	227	610	5e-17	94.4
rs:WP_017311325	DNA topoisomerase I [Fischerella sp. PCC 9339].	25.84	356	225	8	41	387	255	580	5e-17	94.4
rs:XP_006021587	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Alligator sinensis].	23.58	441	257	15	40	453	263	650	5e-17	94.0
rs:WP_047952846	DNA topoisomerase I [Neisseria gonorrhoeae].	23.92	485	265	13	41	454	225	676	5e-17	94.0
rs:WP_025701826	DNA topoisomerase I [Paenibacillus forsythiae].	24.19	430	262	14	50	457	227	614	5e-17	94.0
rs:WP_031471430	DNA topoisomerase I [[Clostridium] aminophilum].	25.12	414	256	11	60	457	240	615	5e-17	94.0
tr:A0A0C5PKD8_LACSK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.27	185	122	3	56	237	10	190	5e-17	89.4
tr:C5RBD7_WEIPA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.69	432	248	16	45	452	255	637	5e-17	94.0
rs:WP_022388599	DNA topoisomerase [Ruminococcus obeum CAG:39].	24.60	439	272	13	34	454	212	609	5e-17	94.0
rs:WP_015925504	DNA topoisomerase I [[Clostridium] cellulolyticum].	25.29	435	268	15	41	454	220	618	5e-17	94.0
rs:WP_040760362	DNA topoisomerase I [Weissella paramesenteroides].	25.69	432	248	16	45	452	241	623	5e-17	94.0
rs:WP_018392335	DNA topoisomerase I [Bacillus sp. 37MA].	23.67	452	278	16	25	452	201	609	5e-17	94.0
rs:WP_013389292	DNA topoisomerase III [Ilyobacter polytropus].	24.42	385	240	16	77	443	270	621	5e-17	94.0
rs:WP_040736674	DNA topoisomerase I [Paenibacillus alvei].	23.70	443	279	13	35	457	211	614	5e-17	94.0
tr:X8K7D9_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.38	484	291	16	2	457	188	624	5e-17	94.0
rs:WP_034194827	hypothetical protein, partial [Burkholderia sp. WP42].	41.51	106	62	0	35	140	240	345	5e-17	91.7
rs:WP_021320765	DNA topoisomerase I [Streptococcus equi].	24.04	416	240	13	61	452	262	625	5e-17	94.0
rs:XP_009640102	PREDICTED: DNA topoisomerase 3-beta-1 [Egretta garzetta].	24.66	438	258	15	25	434	247	640	5e-17	94.0
tr:S4TL54_9CHLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.88	426	258	15	47	452	240	623	5e-17	94.0
rs:WP_010940644	DNA topoisomerase I [Desulfovibrio vulgaris].	24.77	428	263	12	41	452	230	614	5e-17	94.0
tr:A0A078L6H7_9CHLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.65	427	265	15	47	454	240	624	5e-17	94.0
rs:WP_040766049	DNA topoisomerase I [Tsukamurella sp. 1534].	27.11	343	196	11	35	354	250	561	5e-17	94.4
rs:WP_028042355	DNA topoisomerase I [Candidatus Stoquefichus massiliensis].	25.98	408	228	13	65	450	244	599	5e-17	94.0
rs:WP_019773343	DNA topoisomerase I, partial [Streptococcus sobrinus].	23.65	427	250	14	50	452	252	626	5e-17	94.0
rs:WP_028945924	DNA topoisomerase I [Pseudomonas vranovensis].	26.72	393	233	13	68	446	276	627	5e-17	94.0
rs:WP_022966647	topoisomerase I [Pseudomonas caeni].	23.73	413	270	11	40	446	251	624	5e-17	94.0
rs:WP_011170900	DNA topoisomerase I [Methanococcus maripaludis].	24.30	461	276	15	18	454	216	627	5e-17	94.0
rs:XP_008120112	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Anolis carolinensis].	25.06	423	251	17	60	455	294	677	5e-17	94.4
rs:WP_017643397	DNA topoisomerase III [Streptococcus agalactiae].	27.66	329	204	10	61	385	265	563	5e-17	93.6
rs:WP_010114390	topoisomerase I [Acinetobacter sp. P8-3-8].	26.53	426	258	18	40	452	269	652	5e-17	94.0
rs:WP_045186733	DNA topoisomerase I [Pseudomonas sp. 5].	26.46	393	234	13	68	446	276	627	5e-17	94.0
rs:WP_041057468	DNA topoisomerase I [Jeotgalibacillus campisalis].	24.73	457	274	19	27	457	203	615	5e-17	94.0
rs:WP_000179619	DNA topoisomerase I [Streptococcus pneumoniae].	23.96	409	238	14	66	452	254	611	5e-17	94.0
rs:WP_014638935	DNA topoisomerase I [Streptococcus suis].	23.89	406	245	11	65	452	254	613	5e-17	94.0
tr:W7D7J3_9LIST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	23.94	426	267	14	50	457	34	420	5e-17	93.6
rs:XP_001636325	predicted protein [Nematostella vectensis].	24.48	433	263	15	40	453	261	648	5e-17	94.0
rs:WP_038608886	DNA topoisomerase I [Pseudomonas alkylphenolia].	26.46	393	234	13	68	446	276	627	5e-17	94.0
rs:WP_019271676	DNA topoisomerase I [Neisseria sicca].	24.22	483	261	14	43	454	228	676	5e-17	94.0
rs:WP_044908119	DNA topoisomerase I [Lachnospiraceae bacterium MC2017].	25.59	426	260	13	47	454	230	616	5e-17	94.0
rs:WP_047431237	DNA topoisomerase I [Acinetobacter sp. neg1].	27.41	321	193	10	40	356	267	551	5e-17	94.0
rs:XP_012603374	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Microcebus murinus].	25.24	424	249	14	60	455	310	693	5e-17	94.0
rs:XP_012632163	PREDICTED: DNA topoisomerase 3-beta-1 [Microcebus murinus].	23.77	467	272	18	18	453	237	650	5e-17	94.0
rs:XP_003803330	PREDICTED: DNA topoisomerase 3-beta-1 [Otolemur garnettii].	24.07	457	266	17	25	453	247	650	5e-17	94.0
rs:WP_002352040	hypothetical protein, partial [Enterococcus faecium].	35.48	155	91	3	211	365	1	146	5e-17	90.9
rs:WP_031947281	DNA topoisomerase I [Acinetobacter baumannii].	26.93	427	255	19	40	452	266	649	5e-17	94.0
rs:WP_019786482	DNA topoisomerase I, partial [Streptococcus sobrinus].	23.65	427	250	14	50	452	254	628	5e-17	93.6
rs:WP_038674305	DNA topoisomerase I [Streptococcus equi].	24.04	416	240	13	61	452	262	625	5e-17	94.0
rs:WP_005010707	DNA topoisomerase I [Nitrospina gracilis].	26.79	433	245	17	47	452	226	613	5e-17	94.0
tr:A0A077V3Z6_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.71	429	254	18	47	452	226	608	5e-17	94.0
rs:XP_010077639	PREDICTED: DNA topoisomerase 3-beta-1 [Pterocles gutturalis].	24.66	438	258	15	25	434	247	640	5e-17	94.0
rs:WP_031999729	DNA topoisomerase I [Acinetobacter baumannii].	26.93	427	255	19	40	452	266	649	5e-17	94.0
rs:WP_029712355	hypothetical protein, partial [BRC1 bacterium SCGC AAA257-C11].	25.12	426	250	15	47	449	245	624	5e-17	94.0
rs:WP_024532816	DNA topoisomerase I [Streptococcus suis].	23.42	444	263	14	34	452	222	613	5e-17	94.0
tr:K4Z7C0_PAEAL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.70	443	279	13	35	457	181	584	5e-17	94.0
rs:XP_001470217	putative DNA topoisomerase III [Leishmania infantum JPCM5].	23.98	417	259	12	39	434	252	631	5e-17	94.0
rs:XP_012603376	PREDICTED: DNA topoisomerase 3-alpha isoform X4 [Microcebus murinus].	25.24	424	249	14	60	455	220	603	5e-17	94.0
rs:WP_042833103	DNA topoisomerase I [Thermoanaerobacter sp. YS13].	26.59	455	251	20	28	454	213	612	5e-17	94.0
tr:A0A0D6J1U3_MYCSM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.79	392	233	13	41	410	251	610	5e-17	94.0
rs:WP_029662309	DNA topoisomerase I [Streptococcus pneumoniae].	24.69	409	235	14	66	452	254	611	5e-17	94.0
rs:WP_033133268	DNA topoisomerase I [Acinetobacter sp. MN12].	26.76	426	257	18	40	452	267	650	5e-17	94.0
tr:F3CEV4_PSESG	SubName: Full=Orf50 {ECO:0000313|EMBL:EGH17796.1}; Flags: Fragment;	38.13	139	77	2	155	287	7	142	5e-17	88.2
rs:WP_016492045	DNA topoisomerase I [Pseudomonas resinovorans].	24.57	411	265	11	42	446	255	626	5e-17	94.0
rs:WP_011543972	DNA topoisomerase I [Lactobacillus delbrueckii].	26.33	433	247	17	43	452	254	637	5e-17	94.0
rs:WP_012874441	DNA topoisomerase I [Thermobaculum terrenum].	24.94	437	254	18	47	452	233	626	5e-17	94.0
rs:WP_033861012	DNA topoisomerase 1 [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	5e-17	94.0
rs:WP_032876161	DNA topoisomerase I [Acinetobacter baumannii].	27.41	321	193	10	40	356	267	551	5e-17	94.0
rs:XP_007121076	PREDICTED: DNA topoisomerase 3-alpha [Physeter catodon].	25.00	420	255	14	60	455	164	547	5e-17	94.0
rs:WP_021858644	DNA topoisomerase [Firmicutes bacterium CAG:83].	27.13	435	253	15	49	459	231	625	5e-17	94.0
rs:WP_025390203	DNA topoisomerase I [Pseudomonas syringae].	27.14	409	249	16	47	446	259	627	5e-17	94.0
tr:A0A091JBV2_9AVES	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.66	438	258	15	25	434	224	617	6e-17	94.0
rs:WP_003697687	DNA topoisomerase I [Neisseria gonorrhoeae].	23.92	485	265	13	41	454	225	676	6e-17	94.0
rs:XP_012603377	PREDICTED: DNA topoisomerase 3-alpha isoform X5 [Microcebus murinus].	25.24	424	249	14	60	455	123	506	6e-17	94.0
rs:WP_022097363	DNA topoisomerase [Eubacterium eligens CAG:72].	26.06	426	256	14	50	457	229	613	6e-17	93.6
tr:A0A0C9QZN0_9HYME	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.58	415	246	13	69	455	325	700	6e-17	94.0
rs:WP_013780472	DNA topoisomerase I [Mahella australiensis].	24.77	436	269	13	41	457	219	614	6e-17	93.6
rs:WP_002880197	DNA topoisomerase I [Lactobacillus delbrueckii].	26.56	433	246	17	43	452	251	634	6e-17	94.0
rs:WP_036056444	DNA topoisomerase I [Leptotrichia goodfellowii].	25.00	356	214	9	40	379	214	532	6e-17	94.0
rs:WP_009399149	DNA topoisomerase I [Pseudomonas putida].	24.94	401	247	14	77	459	263	627	6e-17	93.6
rs:WP_021614278	DNA topoisomerase I [Actinomyces sp. oral taxon 877].	27.52	367	218	12	42	385	253	594	6e-17	94.0
rs:WP_004826641	DNA topoisomerase I [Acinetobacter bereziniae].	26.97	356	213	12	40	384	268	587	6e-17	94.0
rs:WP_037616756	DNA topoisomerase [Streptococcus sinensis].	25.26	392	246	12	18	399	223	577	6e-17	93.6
rs:XP_010366068	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Rhinopithecus roxellana].	25.34	438	260	14	40	450	289	686	6e-17	94.0
rs:WP_031336601	hypothetical protein [Xylella fastidiosa].	51.85	81	39	0	41	121	1	81	6e-17	87.0
rs:XP_003791095	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha [Otolemur garnettii].	25.71	424	247	14	60	455	316	699	6e-17	94.0
rs:WP_003677938	DNA topoisomerase I [Neisseria cinerea].	24.22	483	261	14	43	454	228	676	6e-17	94.0
rs:WP_032043705	DNA topoisomerase I [Acinetobacter baumannii].	26.93	427	255	19	40	452	266	649	6e-17	94.0
tr:A0A0D6NAU5_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.61	449	260	17	41	452	225	636	6e-17	94.0
rs:WP_046720326	DNA topoisomerase III, partial [Pseudomonas syringae].	39.39	132	77	2	31	159	48	179	6e-17	89.0
rs:WP_000179644	DNA topoisomerase I [Streptococcus pneumoniae].	23.96	409	238	14	66	452	254	611	6e-17	93.6
rs:WP_004774272	DNA topoisomerase I [Acinetobacter sp. NIPH 758].	27.41	321	193	10	40	356	267	551	6e-17	94.0
rs:WP_028514763	DNA topoisomerase I [Ruminococcus flavefaciens].	24.24	429	267	11	43	452	221	610	6e-17	93.6
rs:XP_012713516	PREDICTED: DNA topoisomerase 3-beta-1 [Fundulus heteroclitus].	24.04	441	255	15	40	453	263	650	6e-17	94.0
rs:WP_047920991	DNA topoisomerase I [Neisseria gonorrhoeae].	23.92	485	265	13	41	454	225	676	6e-17	94.0
rs:WP_047953273	DNA topoisomerase I [Neisseria gonorrhoeae].	23.92	485	265	13	41	454	225	676	6e-17	94.0
rs:WP_046332083	DNA topoisomerase I [Lactobacillus kimbladii].	25.44	401	238	14	70	452	256	613	6e-17	93.6
rs:WP_045797922	DNA topoisomerase I [Streptococcus equinus].	24.06	424	252	14	50	452	252	626	6e-17	93.6
rs:WP_040176353	DNA topoisomerase III, partial [Klebsiella pneumoniae].	30.15	199	112	6	277	459	3	190	6e-17	90.9
rs:WP_026393154	DNA topoisomerase I [Acetobacterium dehalogenans].	26.00	427	246	15	50	454	229	607	6e-17	93.6
rs:WP_004818820	DNA topoisomerase I [Acinetobacter guillouiae].	26.97	356	213	12	40	384	268	587	6e-17	94.0
tr:A0A0E0VND2_STAA5	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.71	429	254	18	47	452	226	608	6e-17	93.6
rs:WP_000774787	DNA topoisomerase 1 [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	6e-17	93.6
rs:WP_031786944	DNA topoisomerase I [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	6e-17	93.6
rs:WP_023049409	hypothetical protein [Pseudomonas putida].	25.44	397	250	14	77	459	263	627	6e-17	93.6
rs:WP_000179632	DNA topoisomerase I [Streptococcus pneumoniae].	23.96	409	238	14	66	452	254	611	6e-17	93.6
rs:WP_036491339	DNA topoisomerase I [Neisseria mucosa].	24.43	483	260	14	43	454	228	676	6e-17	94.0
rs:WP_031869532	DNA topoisomerase 1 [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	6e-17	93.6
rs:WP_044679670	DNA topoisomerase I [Streptococcus suis].	23.92	439	267	13	34	452	222	613	6e-17	93.6
rs:XP_012603372	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Microcebus murinus].	25.24	424	249	14	60	455	310	693	6e-17	94.0
rs:WP_044478341	DNA topoisomerase I [Paenibacillus sp. GD11].	24.15	439	269	16	41	457	218	614	6e-17	93.6
rs:XP_010366052	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Rhinopithecus roxellana].	25.66	417	244	13	60	450	227	603	6e-17	94.0
rs:WP_006567147	DNA topoisomerase I [Anaerostipes caccae].	23.53	425	272	11	48	457	227	613	6e-17	93.6
rs:WP_044134826	DNA topoisomerase I, partial [Bacteroides fragilis].	25.23	333	212	11	61	385	263	566	6e-17	93.6
sp:TOP3A_HUMAN	RecName: Full=DNA topoisomerase 3-alpha; EC=5.99.1.2; AltName: Full=DNA topoisomerase III alpha;	25.66	417	244	13	60	450	310	686	6e-17	94.0
rs:WP_015915683	DNA topoisomerase I [Agrobacterium vitis].	25.86	437	267	14	46	452	229	638	6e-17	94.0
rs:WP_005619805	DNA topoisomerase I subunit omega [Ruegeria mobilis].	26.72	464	249	19	41	454	225	647	6e-17	94.0
rs:XP_003198651	PREDICTED: DNA topoisomerase 3-beta-1 [Danio rerio].	24.04	441	255	16	40	453	263	650	6e-17	94.0
tr:A0A094QJY2_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KGA14741.1};	27.44	328	192	10	41	354	256	551	6e-17	94.0
rs:WP_031914685	DNA topoisomerase 1 [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	6e-17	93.6
rs:WP_037573320	DNA topoisomerase I [Staphylococcus chromogenes].	23.76	425	263	15	47	452	224	606	6e-17	93.6
sp:TOP1_STAEQ	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.41	422	258	15	50	452	227	606	6e-17	93.6
rs:WP_000772478	DNA topoisomerase I [Escherichia coli].	24.58	415	241	13	61	455	231	593	6e-17	93.6
rs:WP_033025076	DNA topoisomerase I [Geobacillus sp. CAMR5420].	23.61	487	299	16	1	457	170	613	6e-17	93.6
rs:XP_010229157	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Brachypodium distachyon].	25.34	442	263	14	39	451	94	497	6e-17	94.0
rs:WP_014736718	DNA topoisomerase I [Thermogladius cellulolyticus].	25.79	380	224	13	64	425	279	618	6e-17	93.6
rs:WP_011108421	DNA topoisomerase I [Bacteroides thetaiotaomicron].	25.23	333	212	11	61	385	263	566	6e-17	93.6
rs:WP_039991082	DNA topoisomerase I [Fusobacterium gonidiaformans].	27.41	343	199	10	51	378	226	533	6e-17	93.6
rs:WP_017391319	topoisomerase I [Acinetobacter calcoaceticus].	27.17	427	254	19	40	452	266	649	6e-17	94.0
rs:XP_008530670	PREDICTED: DNA topoisomerase 3-alpha [Equus przewalskii].	25.11	438	261	14	40	450	263	660	6e-17	94.0
rs:WP_027906307	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	26.21	412	257	14	42	446	254	625	6e-17	94.0
rs:WP_024644067	DNA topoisomerase I [Pseudomonas syringae].	27.14	409	249	16	47	446	259	627	6e-17	94.0
rs:WP_021373390	DNA topoisomerase I [Peptoclostridium difficile].	21.79	436	282	10	36	454	215	608	6e-17	93.6
tr:F0R4F1_BACSH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	24.07	378	247	10	21	387	242	590	6e-17	93.6
rs:WP_002270391	DNA topoisomerase I [Streptococcus mutans].	23.89	452	281	14	19	452	213	619	6e-17	93.6
rs:WP_034611665	DNA topoisomerase I [Acinetobacter sp. ETR1].	26.97	356	213	12	40	384	268	587	6e-17	94.0
tr:L8F3C6_MYCSM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.79	392	233	13	41	410	230	589	6e-17	94.0
rs:XP_010991894	PREDICTED: DNA topoisomerase 3-alpha [Camelus dromedarius].	26.42	424	244	14	60	455	285	668	6e-17	94.0
rs:WP_032631710	DNA topoisomerase III, partial [Pseudomonas syringae].	36.03	136	79	1	277	404	6	141	6e-17	87.8
rs:WP_010359499	DNA topoisomerase I [Neisseria gonorrhoeae].	23.92	485	265	13	41	454	225	676	6e-17	93.6
tr:A0A0B3A8L9_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.70	417	235	15	67	453	382	749	6e-17	93.6
rs:WP_029376441	DNA topoisomerase 1 [Staphylococcus epidermidis].	24.41	422	258	15	50	452	227	606	6e-17	93.6
sp:TOP1_THEAC	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	22.86	385	254	11	18	397	218	564	6e-17	93.6
rs:WP_038213506	DNA topoisomerase I [Xenophilus azovorans].	24.57	411	253	14	60	459	247	611	6e-17	93.6
rs:WP_004718025	DNA topoisomerase I [Acinetobacter guillouiae].	26.97	356	213	12	40	384	268	587	6e-17	94.0
rs:WP_042105386	DNA topoisomerase I [Parachlamydiaceae bacterium HS-T3].	26.65	424	247	16	47	449	239	619	6e-17	94.0
rs:WP_039919895	DNA topoisomerase I, partial [Leptotrichia goodfellowii].	25.00	356	214	9	40	379	214	532	6e-17	93.6
tr:F6YMD1_HORSE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.11	438	261	14	40	450	270	667	6e-17	94.0
rs:WP_011697087	DNA topoisomerase I [Syntrophobacter fumaroxidans].	25.92	409	246	13	61	450	248	618	6e-17	93.6
tr:F1QNX4_DANRE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.04	441	255	16	40	453	264	651	6e-17	94.0
rs:WP_021957116	DNA topoisomerase [Eubacterium sp. CAG:115].	26.05	430	251	17	47	452	225	611	6e-17	93.6
rs:WP_036327146	DNA topoisomerase I [Mollicutes bacterium HR2].	25.06	407	244	12	61	451	235	596	6e-17	93.6
tr:B4U2W8_STREM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.04	416	240	13	61	452	265	628	6e-17	93.6
rs:WP_031868161	DNA topoisomerase I [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	6e-17	93.6
rs:WP_012340540	topoisomerase I [Histophilus somni].	26.96	382	224	15	77	446	290	628	6e-17	94.0
rs:WP_043842115	DNA topoisomerase I [Roseivivax atlanticus].	27.14	479	246	19	41	454	225	665	6e-17	94.0
tr:A0A015PAY0_BACFG	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EXY30277.1}; Flags: Fragment;	25.23	333	212	11	61	385	253	556	6e-17	93.2
rs:WP_000179682	DNA topoisomerase I [Streptococcus pneumoniae].	23.77	408	240	13	66	452	254	611	6e-17	93.6
rs:WP_045510901	hypothetical protein [bacterium UASB14].	25.69	432	258	15	47	452	228	622	6e-17	93.6
rs:WP_045434910	DNA topoisomerase I [Acinetobacter calcoaceticus].	27.17	427	254	19	40	452	266	649	6e-17	94.0
rs:WP_002489763	DNA topoisomerase I [Staphylococcus epidermidis].	24.41	422	258	15	50	452	227	606	6e-17	93.6
rs:WP_031903339	DNA topoisomerase I [Staphylococcus aureus].	24.30	428	257	17	47	452	224	606	6e-17	93.6
rs:WP_016164983	DNA topoisomerase I [Acinetobacter sp. CIP 110321].	26.76	426	257	18	40	452	267	650	6e-17	94.0
rs:WP_042380537	DNA topoisomerase I [Geobacillus kaustophilus].	23.61	487	299	16	1	457	170	613	6e-17	93.6
rs:WP_011230711	MULTISPECIES: DNA topoisomerase I [Geobacillus].	23.61	487	299	16	1	457	170	613	6e-17	93.6
rs:WP_042894703	DNA topoisomerase I [Acinetobacter oleivorans].	27.17	427	254	19	40	452	266	649	6e-17	94.0
rs:WP_019313223	DNA topoisomerase I [Streptococcus mutans].	23.89	452	281	14	19	452	213	619	6e-17	93.6
rs:WP_005192225	DNA topoisomerase I [Acinetobacter sp. ANC 4105].	26.76	426	257	18	40	452	267	650	6e-17	94.0
rs:WP_022816092	DNA topoisomerase I [Poribacteria bacterium WGA-3G].	25.64	433	272	16	35	449	220	620	6e-17	93.6
rs:WP_011731080	DNA topoisomerase I [Mycobacterium smegmatis].	26.79	392	233	13	41	410	268	627	7e-17	94.0
rs:WP_000179641	DNA topoisomerase I [Streptococcus pneumoniae].	23.96	409	238	14	66	452	254	611	7e-17	93.6
rs:WP_037564696	DNA topoisomerase I [Staphylococcus agnetis].	24.00	425	262	15	47	452	224	606	7e-17	93.6
rs:WP_004656000	DNA topoisomerase I [Acinetobacter sp. NIPH 809].	26.40	356	215	11	40	384	267	586	7e-17	93.6
rs:WP_007305008	DNA topoisomerase I [Crocosphaera watsonii].	26.74	359	218	11	41	387	249	574	7e-17	93.6
rs:WP_024389804	DNA topoisomerase [Streptococcus suis].	27.30	337	197	11	60	385	264	563	7e-17	93.2
rs:WP_020466884	DNA topoisomerase I [Singulisphaera acidiphila].	27.15	431	242	17	44	454	226	604	7e-17	93.6
rs:XP_011306985	PREDICTED: DNA topoisomerase 3-alpha [Fopius arisanus].	23.18	466	287	15	22	455	274	700	7e-17	94.0
rs:WP_026612485	MULTISPECIES: DNA topoisomerase I [Sinorhizobium/Ensifer group].	25.11	438	266	13	47	452	230	637	7e-17	93.6
rs:WP_015496188	DNA topoisomerase I [Octadecabacter arcticus].	26.70	427	251	15	53	452	237	628	7e-17	93.6
rs:WP_047919122	DNA topoisomerase I [Neisseria gonorrhoeae].	24.22	483	261	14	43	454	228	676	7e-17	93.6
rs:WP_016139347	DNA topoisomerase I [Acinetobacter calcoaceticus].	27.17	427	254	19	40	452	266	649	7e-17	93.6
rs:WP_004641017	DNA topoisomerase I [Acinetobacter calcoaceticus].	27.17	427	254	19	40	452	266	649	7e-17	93.6
rs:WP_043088831	DNA topoisomerase I [Pseudomonas aeruginosa].	25.79	411	240	14	74	459	260	630	7e-17	93.6
rs:WP_025690981	DNA topoisomerase I [Paenibacillus zanthoxyli].	24.19	430	262	14	50	457	227	614	7e-17	93.6
rs:WP_047924076	DNA topoisomerase I [Neisseria gonorrhoeae].	23.92	485	265	13	41	454	225	676	7e-17	93.6
gp:CP002904_1030	DNA topoisomerase I [Streptococcus equi subsp. zooepidemicus ATCC 35246]	24.04	416	240	13	61	452	265	628	7e-17	93.6
rs:WP_005155136	DNA topoisomerase I [Acinetobacter sp. ANC 3929].	26.76	426	257	18	40	452	267	650	7e-17	93.6
rs:WP_009175240	DNA topoisomerase I [Neisseria sp. oral taxon 014].	24.22	483	261	14	43	454	228	676	7e-17	93.6
rs:WP_005210345	DNA topoisomerase I [Acinetobacter sp. NIPH 1867].	26.76	426	257	18	40	452	267	650	7e-17	93.6
tr:U2U8X5_STRPY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.29	425	254	15	50	452	250	624	7e-17	93.6
rs:WP_006803964	DNA topoisomerase I [Leptotrichia hofstadii].	27.33	333	187	10	65	379	237	532	7e-17	93.6
rs:WP_002283689	DNA topoisomerase I [Streptococcus mutans].	23.89	452	281	14	19	452	213	619	7e-17	93.6
rs:WP_039150118	DNA topoisomerase I [Leisingera sp. ANG-DT].	25.98	458	260	17	41	454	225	647	7e-17	93.6
rs:WP_002309561	DNA topoisomerase I [Enterococcus faecium].	24.50	449	269	15	34	457	211	614	7e-17	93.6
rs:WP_013346029	topoisomerase I [Ferrimonas balearica].	25.24	420	258	15	40	446	257	633	7e-17	93.6
rs:WP_025767428	hypothetical protein [Vibrio parahaemolyticus].	24.66	442	275	16	32	459	220	617	7e-17	94.0
rs:WP_016279166	DNA topoisomerase I [Lachnospiraceae bacterium A4].	23.27	434	281	10	36	454	215	611	7e-17	93.6
rs:WP_026490871	DNA topoisomerase I [Butyrivibrio sp. XPD2002].	23.64	423	268	12	48	454	232	615	7e-17	93.6
rs:WP_035825898	DNA topoisomerase I [Crocosphaera watsonii].	26.74	359	218	11	41	387	249	574	7e-17	93.6
tr:G7ZMZ8_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.24	425	261	15	47	452	226	608	7e-17	93.6
rs:WP_015374403	MULTISPECIES: DNA topoisomerase I [Geobacillus].	23.61	487	299	16	1	457	170	613	7e-17	93.6
rs:WP_048136181	DNA topoisomerase [Methanosarcina sp. 1.H.T.1A.1].	25.23	436	280	14	34	454	238	642	7e-17	93.6
tr:U2ILG3_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.65	427	250	14	50	452	256	630	7e-17	93.6
rs:XP_006175691	PREDICTED: DNA topoisomerase 3-alpha [Camelus ferus].	26.01	446	259	16	40	455	231	635	7e-17	93.6
rs:WP_000864636	MULTISPECIES: DNA topoisomerase [Bacillus cereus group].	32.94	170	109	4	67	233	278	445	7e-17	92.8
rs:WP_026798579	MULTISPECIES: DNA topoisomerase I [Planktothrix].	26.32	380	228	12	41	401	260	606	7e-17	93.6
rs:XP_010229158	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Brachypodium distachyon].	25.34	442	263	14	39	451	69	472	7e-17	93.6
rs:WP_031867779	DNA topoisomerase 1 [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	7e-17	93.6
tr:G1V001_9DELT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGW42406.1};	57.33	75	30	1	270	344	2	74	7e-17	86.3
rs:WP_047067934	DNA topoisomerase I [Brevibacillus formosus].	24.77	432	258	15	49	457	226	613	7e-17	93.6
rs:WP_005963182	DNA topoisomerase TopA [Actinomyces cardiffensis].	26.43	367	219	12	42	384	253	592	7e-17	93.6
rs:WP_003775245	DNA topoisomerase I [Neisseria elongata].	24.12	481	264	12	43	454	228	676	7e-17	93.6
rs:WP_002244762	DNA topoisomerase I [Neisseria meningitidis].	23.35	484	269	11	41	454	225	676	7e-17	93.6
rs:XP_004289288	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Fragaria vesca subsp. vesca].	24.83	443	265	12	39	451	261	665	7e-17	93.6
rs:WP_017390083	topoisomerase I [Acinetobacter calcoaceticus].	27.17	427	254	19	40	452	266	649	7e-17	93.6
rs:WP_026943886	DNA topoisomerase I [Helicobacter rodentium].	24.70	421	255	14	47	450	227	602	7e-17	93.6
tr:A0A077VUX2_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.24	425	261	15	47	452	226	608	7e-17	93.6
rs:WP_042348935	DNA topoisomerase I [Bacillus sp. G2(2012b)].	22.75	422	267	13	50	452	227	608	7e-17	93.6
rs:XP_001469727	putative DNA topoisomerase III [Leishmania infantum JPCM5].	26.48	355	218	8	37	379	244	567	7e-17	93.6
rs:WP_005037005	DNA topoisomerase I [Acinetobacter calcoaceticus].	27.17	427	254	19	40	452	266	649	7e-17	93.6
rs:WP_041584091	DNA topoisomerase I [Bacteroides salanitronis].	24.07	378	247	10	21	387	220	568	7e-17	93.2
rs:XP_006341743	PREDICTED: DNA topoisomerase 3-alpha-like [Solanum tuberosum].	24.31	469	282	15	18	452	246	675	7e-17	93.6
tr:B4RPY3_NEIG2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.22	483	261	14	43	454	244	692	7e-17	93.6
rs:XP_001918241	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha [Equus caballus].	25.11	438	261	14	40	450	269	666	7e-17	93.6
rs:WP_033868999	DNA topoisomerase 1 [Staphylococcus aureus].	24.24	429	256	17	47	452	224	606	7e-17	93.6
rs:WP_000774778	DNA topoisomerase I [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	7e-17	93.6
rs:WP_047434994	DNA topoisomerase I [Staphylococcus aureus].	24.24	425	261	15	47	452	224	606	7e-17	93.6
rs:WP_002997891	DNA topoisomerase I [Streptococcus downei].	23.77	446	259	15	34	452	237	628	7e-17	93.6
tr:A0A0F6BC21_CORPF	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:ADK28018.1}; EC=5.99.1.2 {ECO:0000313|EMBL:ADK28018.1};	26.15	371	227	11	31	384	291	631	7e-17	93.6
rs:XP_010229156	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Brachypodium distachyon].	25.28	443	264	14	39	452	269	673	7e-17	93.6
rs:WP_013999415	DNA topoisomerase I [Methanococcus maripaludis].	24.30	461	276	15	18	454	216	627	7e-17	93.6
tr:D0GKB0_9FUSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	356	214	9	40	379	227	545	7e-17	93.6
rs:WP_019776889	DNA topoisomerase I [Streptococcus sobrinus].	23.65	427	250	14	50	452	254	628	7e-17	93.6
tr:F7LSI8_9BACE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGN05987.1};	31.87	160	105	3	49	208	268	423	7e-17	92.4
tr:C8S1H8_9RHOB	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.72	404	234	15	47	427	229	597	7e-17	93.6
tr:G8F1W3_MACMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.85	457	267	17	25	453	247	650	7e-17	93.6
rs:WP_016670597	DNA topoisomerase I [Neisseria meningitidis].	24.22	483	261	14	43	454	228	676	7e-17	93.6
rs:WP_007746465	DNA topoisomerase I [Oenococcus kitaharae].	24.47	425	262	10	44	452	228	609	7e-17	93.6
rs:WP_009393140	DNA topoisomerase I [Acinetobacter sp. WC-141].	27.17	427	254	19	40	452	266	649	7e-17	93.6
rs:WP_042988647	MULTISPECIES: hypothetical protein [Vibrio].	26.15	413	230	17	70	458	237	598	7e-17	93.6
tr:H9JC36_BOMMO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.18	413	246	12	65	451	225	600	7e-17	93.6
rs:WP_021833112	DNA topoisomerase I [Crocosphaera watsonii].	26.74	359	218	11	41	387	174	499	7e-17	93.6
rs:WP_019789487	DNA topoisomerase I, partial [Streptococcus sobrinus].	23.65	427	250	14	50	452	149	523	7e-17	93.2
rs:WP_024992856	DNA topoisomerase, partial [Prevotella amnii].	32.99	197	122	5	232	426	6	194	7e-17	90.5
rs:WP_007310208	DNA topoisomerase I [Crocosphaera watsonii].	26.74	359	218	11	41	387	220	545	7e-17	93.6
rs:WP_013792006	topoisomerase I [Pseudomonas fulva].	26.21	412	257	14	42	446	254	625	7e-17	93.6
tr:A0A077VAY5_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.24	425	261	15	47	452	226	608	7e-17	93.6
rs:WP_010360929	DNA topoisomerase I [Neisseria gonorrhoeae].	23.92	485	265	13	41	454	225	676	7e-17	93.6
rs:WP_033910279	DNA topoisomerase I [Neisseria gonorrhoeae].	23.92	485	265	13	41	454	225	676	7e-17	93.6
rs:XP_010366045	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Rhinopithecus roxellana].	25.66	417	244	13	60	450	310	686	7e-17	93.6
gp:AJ938182_1074	DNA topoisomerase I [Staphylococcus aureus RF122]	25.00	428	252	18	48	452	227	608	7e-17	93.6
tr:I7L3U8_NEIME	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.22	483	261	14	43	454	281	729	7e-17	93.6
rs:XP_010971510	PREDICTED: DNA topoisomerase 3-alpha [Camelus bactrianus].	26.42	424	244	14	60	455	253	636	7e-17	93.6
rs:WP_011868545	DNA topoisomerase I [Methanococcus maripaludis].	23.62	453	289	14	18	454	216	627	7e-17	93.6
rs:WP_005218427	DNA topoisomerase I [Acinetobacter sp. ANC 3862].	26.76	426	257	18	40	452	267	650	7e-17	93.6
tr:J9GJD1_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EJW99689.1}; Flags: Fragment;	27.96	304	185	8	40	340	1	273	7e-17	90.9
rs:WP_017771170	MULTISPECIES: DNA topoisomerase III [Streptococcus].	24.55	387	255	10	18	399	223	577	7e-17	93.2
rs:WP_000259054	DNA topoisomerase III [Streptococcus agalactiae].	25.81	372	241	11	18	385	223	563	7e-17	93.2
rs:WP_019773825	DNA topoisomerase I, partial [Streptococcus sobrinus].	23.65	444	262	15	34	452	156	547	7e-17	93.2
rs:WP_036676479	DNA topoisomerase I [Paenibacillus sp. MSt1].	24.63	471	284	15	18	457	187	617	7e-17	93.6
rs:WP_003456151	topoisomerase I - like protein, partial [Pseudomonas aeruginosa].	25.55	411	241	14	74	459	72	442	7e-17	92.4
rs:WP_023887959	DNA topoisomerase I [Eikenella corrodens].	25.00	416	258	11	54	452	240	618	7e-17	93.6
rs:WP_005302100	DNA topoisomerase I [Acinetobacter sp. NIPH 542].	27.17	427	254	19	40	452	266	649	7e-17	93.6
rs:WP_019770716	DNA topoisomerase I [Streptococcus sobrinus].	23.65	444	262	15	34	452	237	628	7e-17	93.6
tr:A0A099ZL27_TINGU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.66	438	258	15	25	434	224	617	7e-17	93.6
rs:WP_043299032	DNA topoisomerase I [Pseudomonas sp. HMP271].	25.37	402	244	13	68	452	273	635	7e-17	93.6
tr:E6MFE6_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.39	451	258	15	47	452	225	637	8e-17	93.2
rs:WP_027537100	DNA topoisomerase I [Bradyrhizobium sp. URHA0002].	25.73	443	263	13	45	454	228	637	8e-17	93.6
rs:WP_026788352	DNA topoisomerase I [Planktothrix rubescens].	26.32	380	228	12	41	401	260	606	8e-17	93.6
rs:XP_011465095	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Fragaria vesca subsp. vesca].	24.83	443	265	12	39	451	261	665	8e-17	93.6
rs:WP_047526440	DNA topoisomerase I [Staphylococcus aureus].	24.24	425	261	15	47	452	224	606	8e-17	93.2
rs:WP_039174320	DNA topoisomerase I [Leisingera sp. ANG-S5].	25.76	458	261	17	41	454	225	647	8e-17	93.6
rs:WP_019298345	MULTISPECIES: DNA topoisomerase I [Leisingera].	25.76	458	261	17	41	454	225	647	8e-17	93.6
rs:WP_021321700	DNA topoisomerase I [Geobacillus sp. A8].	23.61	487	299	16	1	457	170	613	8e-17	93.2
rs:WP_002345057	DNA topoisomerase 1 [Enterococcus faecium].	24.50	449	269	15	34	457	211	614	8e-17	93.2
rs:WP_019792460	DNA topoisomerase I, partial [Streptococcus sobrinus].	23.65	427	250	14	50	452	211	585	8e-17	93.2
rs:WP_000179637	DNA topoisomerase I [Streptococcus pneumoniae].	23.96	409	238	14	66	452	254	611	8e-17	93.2
gp:HSU43431_2	DNA topoisomerase III [Homo sapiens]	25.66	417	244	13	60	450	285	661	8e-17	93.6
tr:S7N8C3_MYOBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.58	441	257	16	40	453	263	650	8e-17	93.6
rs:WP_048163680	DNA topoisomerase [Methanosarcina sp. 1.H.A.2.2].	25.23	436	280	14	34	454	238	642	8e-17	93.6
rs:WP_025457058	DNA topoisomerase I [Neisseria polysaccharea].	24.22	483	261	14	43	454	228	676	8e-17	93.6
tr:U3DN79_CALJA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.47	424	248	14	60	455	310	693	8e-17	93.6
rs:WP_043746353	DNA topoisomerase I [Oceanicola sp. 22II-S11g].	27.33	439	258	16	41	454	225	627	8e-17	93.6
rs:WP_038671386	DNA topoisomerase I [Pelosinus sp. UFO1].	25.42	417	251	12	60	457	239	614	8e-17	93.2
rs:WP_003105989	DNA topoisomerase I [Streptococcus parauberis].	22.95	440	270	14	34	452	234	625	8e-17	93.2
rs:WP_026791387	DNA topoisomerase I [Pleomorphomonas oryzae].	27.05	451	256	18	39	452	221	635	8e-17	93.6
rs:WP_003654752	topoisomerase I [Acinetobacter calcoaceticus].	27.17	427	254	19	40	452	266	649	8e-17	93.6
rs:WP_045181206	DNA topoisomerase I [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	8e-17	93.2
tr:T2JG30_CROWT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.74	359	218	11	41	387	249	574	8e-17	93.6
rs:XP_005504604	PREDICTED: DNA topoisomerase 3-alpha [Columba livia].	25.56	446	265	16	39	456	288	694	8e-17	93.6
tr:U3CUM4_CALJA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.47	424	248	14	60	455	310	693	8e-17	93.6
rs:WP_046347030	DNA topoisomerase I [Sphingomonas changbaiensis].	28.64	412	240	13	60	452	241	617	8e-17	93.6
tr:I1H9D9_BRADI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.28	443	264	14	39	452	269	673	8e-17	93.6
rs:WP_019795444	DNA topoisomerase I [Streptococcus sobrinus].	23.65	427	250	14	50	452	254	628	8e-17	93.2
rs:WP_039189441	DNA topoisomerase I [Leisingera sp. ANG-M6].	25.76	458	261	17	41	454	225	647	8e-17	93.6
rs:WP_007205640	DNA topoisomerase I [Loktanella vestfoldensis].	27.08	432	256	16	47	454	231	627	8e-17	93.6
rs:WP_044499834	DNA topoisomerase I [Pseudomonas sp. 12M76_air].	26.00	423	250	15	40	446	250	625	8e-17	93.6
rs:XP_005391746	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Chinchilla lanigera].	23.81	441	256	16	40	453	263	650	8e-17	93.6
rs:XP_010218989	PREDICTED: DNA topoisomerase 3-beta-1 [Tinamus guttatus].	24.66	438	258	15	25	434	247	640	8e-17	93.6
rs:WP_022025442	DNA topoisomerase [Clostridium sp. CAG:75].	23.94	426	269	11	48	457	227	613	8e-17	93.2
rs:WP_003824719	DNA topoisomerase I [Eikenella corrodens].	25.41	429	266	11	41	452	227	618	8e-17	93.6
rs:WP_000774789	DNA topoisomerase I [Staphylococcus argenteus].	24.24	425	261	15	47	452	224	606	8e-17	93.2
rs:WP_031656455	DNA topoisomerase I [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	8e-17	93.6
tr:D1NFZ2_HAEIF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	42.05	88	51	0	41	128	1	88	8e-17	86.3
rs:WP_047868693	DNA topoisomerase I [Nocardiopsis sp. RV163].	25.49	357	216	11	40	379	275	598	8e-17	93.6
rs:WP_021397791	DNA topoisomerase I [Peptoclostridium difficile].	21.79	436	282	10	36	454	215	608	8e-17	93.2
rs:XP_007953639	PREDICTED: DNA topoisomerase 3-beta-1 [Orycteropus afer afer].	24.14	377	229	12	40	397	252	590	8e-17	93.6
rs:WP_013199013	topoisomerase I [Acinetobacter oleivorans].	27.17	427	254	19	40	452	266	649	8e-17	93.6
rs:WP_002442541	MULTISPECIES: DNA topoisomerase I [Staphylococcus].	23.53	425	264	14	47	452	224	606	8e-17	93.2
rs:WP_039646065	DNA topoisomerase I [Staphylococcus hyicus].	24.24	429	261	16	43	452	223	606	8e-17	93.2
rs:WP_018869175	DNA topoisomerase I [Thioalkalivibrio sp. ALgr3].	28.27	329	183	8	36	350	233	522	8e-17	93.6
rs:WP_046215351	DNA topoisomerase I [Paenibacillus wulumuqiensis].	24.37	435	261	15	47	457	224	614	8e-17	93.2
tr:J2I0X1_9BACL	SubName: Full=Topoisomerase IA {ECO:0000313|EMBL:EJL42083.1};	34.97	143	89	2	257	396	1	142	8e-17	90.1
rs:XP_007906923	PREDICTED: DNA topoisomerase 3-beta-1 [Callorhinchus milii].	24.40	455	253	16	36	453	249	649	8e-17	93.6
rs:WP_014248084	DNA topoisomerase I [Azospirillum lipoferum].	26.32	475	280	18	13	454	203	640	8e-17	93.6
rs:XP_008994684	PREDICTED: DNA topoisomerase 3-alpha [Callithrix jacchus].	25.47	424	248	14	60	455	310	693	8e-17	93.6
rs:WP_024544176	DNA topoisomerase I [Mycoplasma salivarium].	25.99	404	225	13	65	449	249	597	8e-17	93.2
rs:WP_011888870	DNA topoisomerase I [Streptococcus pyogenes].	22.99	422	259	14	50	452	250	624	8e-17	93.2
rs:WP_023660707	DNA topoisomerase I [Pseudomonas taiwanensis].	25.44	397	250	14	77	459	263	627	8e-17	93.2
tr:A0A077TXL4_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.24	425	261	15	47	452	226	608	8e-17	93.2
rs:WP_048183440	DNA topoisomerase [Methanosarcina siciliae].	24.67	454	266	16	31	454	235	642	8e-17	93.6
tr:J4WI89_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.23	253	150	9	37	286	225	456	8e-17	92.4
rs:WP_039679626	DNA topoisomerase I [Terrisporobacter othiniensis].	21.77	441	280	10	31	454	216	608	8e-17	93.2
tr:C2HAA3_ENTFC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.50	449	269	15	34	457	229	632	8e-17	93.2
rs:WP_011025719	DNA topoisomerase I [Caldanaerobacter subterraneus].	27.01	411	237	15	69	457	247	616	8e-17	93.2
rs:WP_004794819	DNA topoisomerase I [Acinetobacter sp. NIPH 817].	27.17	427	254	19	40	452	266	649	8e-17	93.6
rs:WP_031911407	DNA topoisomerase I [Staphylococcus aureus].	25.00	424	249	18	52	452	229	606	8e-17	93.2
rs:WP_034909951	DNA topoisomerase, partial [Peptostreptococcaceae bacterium OBRC8].	31.23	253	150	9	37	286	225	456	8e-17	92.4
rs:WP_040639880	DNA topoisomerase I [Pseudoramibacter alactolyticus].	24.39	451	258	15	47	452	226	638	8e-17	93.2
rs:XP_005391751	PREDICTED: DNA topoisomerase 3-beta-1 isoform X6 [Chinchilla lanigera].	23.81	441	256	16	40	453	166	553	8e-17	93.2
rs:WP_021792813	hypothetical protein [Thermoplasmatales archaeon E-plasma].	24.32	366	233	10	34	393	238	565	8e-17	93.2
tr:S7SXQ4_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.61	487	299	16	1	457	193	636	8e-17	93.2
rs:WP_014704495	DNA topoisomerase I [Methylophaga frappieri].	26.59	410	246	15	61	452	248	620	8e-17	93.2
rs:XP_004932606	PREDICTED: DNA topoisomerase 3-alpha-like [Bombyx mori].	25.18	413	246	12	65	451	282	657	8e-17	93.6
rs:WP_026782988	DNA topoisomerase I [Pleomorphomonas koreensis].	27.59	453	251	19	39	452	221	635	8e-17	93.6
rs:WP_035258168	DNA topoisomerase I [Actibacterium mucosum].	25.93	432	262	11	47	454	231	628	8e-17	93.6
rs:WP_024590097	MULTISPECIES: DNA topoisomerase I [Pseudoalteromonas].	26.63	368	222	12	42	395	257	590	8e-17	93.6
rs:WP_039129857	DNA topoisomerase I [Leisingera sp. ANG-Vp].	26.24	465	250	18	41	454	225	647	8e-17	93.6
rs:WP_013297943	DNA topoisomerase I [Thermoanaerobacterium thermosaccharolyticum].	26.28	411	231	16	69	454	247	610	8e-17	93.2
rs:XP_005147810	PREDICTED: DNA topoisomerase 3-beta-1 [Melopsittacus undulatus].	24.64	422	247	14	40	434	263	640	8e-17	93.6
tr:A0A0F2L5P6_9CREN	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:KJR71785.1};	26.33	338	208	8	24	354	236	539	9e-17	93.2
rs:WP_004781880	DNA topoisomerase I [Acinetobacter sp. NIPH 899].	26.97	356	213	12	40	384	268	587	9e-17	93.6
rs:WP_047000611	DNA topoisomerase I [Clostridium beijerinckii].	22.46	423	275	9	47	454	224	608	9e-17	93.2
rs:WP_005644977	topoisomerase I [Haemophilus haemolyticus].	26.12	379	231	14	77	446	290	628	9e-17	93.6
tr:A0A0F2L2W0_9CREN	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:KJR71783.1};	26.30	346	198	9	24	354	236	539	9e-17	93.2
rs:WP_005229621	DNA topoisomerase I [Enterococcus casseliflavus].	23.08	442	284	15	34	457	211	614	9e-17	93.2
rs:WP_044145816	DNA topoisomerase I, partial [Enterococcus faecium].	25.25	404	235	13	77	457	255	614	9e-17	93.2
sp:TOP1_STAAB	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.77	428	253	18	48	452	225	606	9e-17	93.2
rs:WP_007115615	DNA topoisomerase I, partial [Enhydrobacter aerosaccus].	27.20	375	209	14	1	354	250	581	9e-17	93.2
tr:J8Z6D6_ENTFC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.50	449	269	15	34	457	229	632	9e-17	93.2
rs:WP_045928058	DNA topoisomerase I [Lactobacillus kullabergensis].	24.65	430	263	14	41	452	227	613	9e-17	93.2
rs:WP_028798425	DNA topoisomerase I [Streptococcus sobrinus].	23.65	427	250	14	50	452	254	628	9e-17	93.2
rs:WP_013238946	hypothetical protein [Clostridium ljungdahlii].	24.11	419	278	12	47	446	251	648	9e-17	93.2
tr:U7UTY2_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.69	409	241	13	65	452	257	619	9e-17	93.2
rs:WP_002240958	DNA topoisomerase I [Neisseria meningitidis].	24.22	483	261	14	43	454	228	676	9e-17	93.2
tr:L0DLK2_SINAD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.15	431	242	17	44	454	295	673	9e-17	93.2
rs:WP_010128307	topoisomerase I [Haemophilus sputorum].	25.00	468	278	18	3	452	227	639	9e-17	93.2
rs:WP_006036001	DNA topoisomerase I [Rickettsiella grylli].	26.26	438	256	17	44	452	232	631	9e-17	93.2
rs:XP_005334534	PREDICTED: DNA topoisomerase 3-beta-1 [Ictidomys tridecemlineatus].	23.85	457	267	17	25	453	247	650	9e-17	93.2
rs:WP_003700733	DNA topoisomerase I [Neisseria gonorrhoeae].	24.22	483	261	14	43	454	228	676	9e-17	93.2
rs:WP_039180480	DNA topoisomerase I [Leisingera sp. ANG-M7].	26.20	458	259	17	41	454	225	647	9e-17	93.2
rs:WP_019768655	DNA topoisomerase I [Streptococcus sobrinus].	23.65	427	250	14	50	452	254	628	9e-17	93.2
rs:WP_005776835	MULTISPECIES: DNA topoisomerase III [Bacteroides].	24.37	394	242	12	21	395	220	576	9e-17	92.8
rs:WP_026610181	DNA topoisomerase I [Methylocaldum szegediense].	26.26	438	245	18	44	452	232	620	9e-17	93.2
rs:WP_002363152	DNA topoisomerase, partial [Enterococcus faecium].	30.17	232	150	5	57	285	268	490	9e-17	92.8
rs:WP_016206342	DNA topoisomerase I [Clostridium sartagoforme].	22.46	423	275	9	47	454	224	608	9e-17	93.2
rs:WP_002313870	DNA topoisomerase I [Enterococcus faecium].	25.19	405	234	14	77	457	255	614	9e-17	93.2
rs:WP_047926217	DNA topoisomerase I [Neisseria gonorrhoeae].	24.22	483	261	14	43	454	228	676	9e-17	93.2
rs:XP_012551245	PREDICTED: DNA topoisomerase 3-alpha [Bombyx mori].	25.18	413	246	12	65	451	313	688	9e-17	93.6
tr:A0A074LLS2_9BACL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.25	408	251	14	66	454	244	616	9e-17	93.2
tr:G3QKQ6_GORGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.74	439	258	14	40	450	289	687	9e-17	93.6
rs:WP_046953148	DNA topoisomerase I [Haemophilus haemolyticus].	26.12	379	231	14	77	446	290	628	9e-17	93.2
tr:S4EF11_ENTFC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.55	448	270	14	34	457	229	632	9e-17	93.2
rs:WP_016688293	DNA topoisomerase I [Neisseria sicca].	23.71	485	266	13	41	454	225	676	9e-17	93.2
rs:WP_020413102	topoisomerase I [Microbulbifer variabilis].	26.33	376	232	12	77	446	296	632	9e-17	93.2
rs:WP_045442954	DNA topoisomerase I, partial [alpha proteobacterium MA2].	25.52	435	246	14	51	452	245	634	9e-17	93.2
rs:WP_042085044	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	26.69	356	214	12	40	384	268	587	9e-17	93.2
rs:WP_034808918	DNA topoisomerase I [Exiguobacterium sp. AB2].	24.76	416	263	12	56	454	232	614	9e-17	93.2
rs:WP_007560996	DNA topoisomerase III [Bacteroides plebeius].	23.60	394	245	12	21	395	220	576	9e-17	92.8
rs:WP_005398276	DNA topoisomerase I [Helcococcus kunzii].	23.62	470	272	16	18	452	187	604	9e-17	93.2
rs:WP_025718462	DNA topoisomerase I [Paenibacillus sp. 1-18].	24.94	413	250	15	65	457	242	614	9e-17	93.2
rs:WP_036101696	DNA topoisomerase I [Listeria riparia].	23.71	426	268	14	50	457	227	613	9e-17	93.2
rs:WP_004668544	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	26.79	321	195	10	40	356	267	551	9e-17	93.2
gp:CP003385_222	DNA topoisomerase I [Corynebacterium pseudotuberculosis P54B96]	26.15	371	227	11	31	384	249	589	9e-17	93.2
rs:WP_021996854	DNA topoisomerase [Clostridium sp. CAG:780].	23.02	417	281	10	47	454	226	611	9e-17	93.2
rs:WP_018297915	DNA topoisomerase I [Corynebacterium lubricantis].	28.31	325	187	12	41	354	263	552	9e-17	93.2
rs:XP_002004036	GI18230 [Drosophila mojavensis].	25.23	444	263	15	37	451	253	656	9e-17	93.6
rs:WP_045607034	DNA topoisomerase I [Streptococcus mitis].	24.21	409	237	14	66	452	254	611	9e-17	93.2
rs:WP_012606724	DNA topoisomerase I [Acidithiobacillus ferrooxidans].	28.67	415	242	16	43	445	222	594	9e-17	93.2
rs:WP_046643722	DNA topoisomerase I [Turicella otitidis].	27.50	320	196	9	47	356	266	559	9e-17	93.2
rs:WP_009126193	DNA topoisomerase I [Bacteroides fluxus].	28.44	320	182	11	36	340	201	488	9e-17	93.2
tr:C6M8I2_NEISI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.22	483	261	14	43	454	250	698	9e-17	93.2
rs:XP_011817025	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Colobus angolensis palliatus].	25.66	417	244	13	60	450	310	686	9e-17	93.2
rs:WP_032092645	DNA topoisomerase I [Necropsobacter rosorum].	26.91	379	228	14	77	446	290	628	9e-17	93.2
rs:WP_044921529	hypothetical protein [Anaerostipes hadrus].	25.37	272	172	8	74	337	278	526	1e-16	93.2
rs:WP_012073135	topoisomerase I [Actinobacillus succinogenes].	26.65	379	229	13	77	446	290	628	1e-16	93.2
gpu:CP011952_1924	93.2	24.88	430	265	14	46	457	237	626	1e-16
rs:WP_044939746	DNA topoisomerase I [Blautia schinkii].	23.80	437	278	13	34	454	212	609	1e-16	93.2
rs:WP_013546559	DNA topoisomerase I [Bacteroides helcogenes].	29.85	268	152	10	77	340	253	488	1e-16	93.2
rs:WP_009312695	MULTISPECIES: DNA topoisomerase I [Neisseria].	24.22	483	261	14	43	454	228	676	1e-16	93.2
rs:WP_002245788	DNA topoisomerase I [Neisseria meningitidis].	24.22	483	261	14	43	454	228	676	1e-16	93.2
rs:WP_014522099	DNA topoisomerase I [Corynebacterium pseudotuberculosis].	26.15	371	227	11	31	384	249	589	1e-16	93.2
rs:WP_000774783	DNA topoisomerase I [Staphylococcus aureus].	24.24	425	261	15	47	452	224	606	1e-16	93.2
rs:WP_042207152	DNA topoisomerase I [Paenibacillus durus].	25.35	434	252	17	50	457	227	614	1e-16	93.2
rs:XP_006140260	PREDICTED: DNA topoisomerase 3-beta-1 [Tupaia chinensis].	22.90	441	260	15	40	453	263	650	1e-16	93.2
rs:WP_005291614	DNA topoisomerase I [Acinetobacter sp. NIPH 2100].	26.76	426	257	18	40	452	267	650	1e-16	93.2
rs:WP_032870742	DNA topoisomerase I [Acinetobacter baumannii].	27.41	321	193	10	40	356	267	551	1e-16	93.2
rs:WP_021750753	MULTISPECIES: DNA topoisomerase I [Oscillibacter].	26.22	431	262	12	48	459	229	622	1e-16	93.2
rs:WP_015650175	DNA topoisomerase I subunit omega [Corynebacterium callunae].	26.18	340	204	9	31	354	253	561	1e-16	93.2
rs:WP_004601140	DNA topoisomerase I [Turicella otitidis].	27.50	320	196	9	47	356	266	559	1e-16	93.2
rs:WP_022350694	GTP-sensing transcriptional pleiotropic repressor CodY [Firmicutes bacterium CAG:534].	23.22	422	271	10	48	454	227	610	1e-16	93.2
rs:WP_042644165	DNA topoisomerase I [Mesorhizobium sp. ORS3359].	26.56	448	257	19	41	452	224	635	1e-16	93.2
rs:WP_027429125	DNA topoisomerase I [Lachnospiraceae bacterium AD3010].	26.87	402	234	16	74	454	257	619	1e-16	93.2
rs:WP_036085525	DNA topoisomerase I [Listeria booriae].	23.71	426	268	14	50	457	227	613	1e-16	93.2
rs:XP_006099576	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Myotis lucifugus].	23.58	441	257	16	40	453	127	514	1e-16	93.2
rs:WP_035055313	DNA topoisomerase I, partial [Desulfuromonas sp. TF].	25.75	431	258	15	45	454	230	619	1e-16	93.2
rs:WP_031643907	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	25.55	411	241	14	74	459	95	465	1e-16	92.4
rs:WP_010125844	DNA topoisomerase I [Sphingomonas sp. KC8].	27.31	454	246	15	34	452	225	629	1e-16	93.2
tr:D9QDZ9_CORP2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.15	371	227	11	31	384	255	595	1e-16	93.2
rs:XP_009622053	PREDICTED: DNA topoisomerase 3-alpha isoform X5 [Nicotiana tomentosiformis].	24.79	480	280	17	18	459	248	684	1e-16	93.2
rs:WP_004587792	DNA topoisomerase I subunit omega [Pseudoalteromonas agarivorans].	25.59	422	262	14	36	446	251	631	1e-16	93.2
rs:WP_025951077	MULTISPECIES: DNA topoisomerase I [Geobacillus].	23.61	487	299	16	1	457	170	613	1e-16	92.8
rs:WP_009534199	DNA topoisomerase I [Oribacterium parvum].	24.39	410	257	11	60	454	239	610	1e-16	92.8
rs:WP_007069521	DNA topoisomerase I [Dialister invisus].	25.28	439	264	16	38	454	245	641	1e-16	93.2
rs:XP_004628014	PREDICTED: DNA topoisomerase 3-beta-1 [Octodon degus].	23.58	441	257	16	40	453	263	650	1e-16	93.2
tr:I2NWJ9_NEISI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.22	483	261	14	43	454	250	698	1e-16	93.2
rs:WP_031770059	DNA topoisomerase I [Staphylococcus aureus].	24.48	429	255	18	47	452	224	606	1e-16	92.8
rs:WP_006429603	DNA topoisomerase I [Natrinema versiforme].	22.51	422	285	11	40	454	246	632	1e-16	93.2
rs:WP_002290218	DNA topoisomerase I [Enterococcus faecium].	25.25	404	235	13	77	457	255	614	1e-16	92.8
rs:XP_011817027	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Colobus angolensis palliatus].	25.66	417	244	13	60	450	215	591	1e-16	93.2
rs:WP_019781775	hypothetical protein [Streptococcus sobrinus].	26.39	341	206	11	71	404	276	578	1e-16	92.8
gpu:CP012022_216	93.2	26.15	371	227	11	31	384	249	589	1e-16
rs:WP_047429580	DNA topoisomerase I [Staphylococcus aureus].	24.24	425	261	15	47	452	224	606	1e-16	92.8
rs:WP_005377513	DNA topoisomerase I [Veillonella atypica].	24.37	476	300	16	1	454	233	670	1e-16	93.2
rs:WP_042539705	DNA topoisomerase I [Microbacterium sp. MEJ108Y].	30.70	316	172	13	51	356	267	545	1e-16	93.2
rs:WP_043030795	DNA topoisomerase I [Streptococcus equi].	23.80	416	241	13	61	452	262	625	1e-16	92.8
rs:XP_005256833	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Homo sapiens].	25.66	417	244	13	60	450	215	591	1e-16	93.2
rs:WP_017650048	DNA topoisomerase [Streptococcus agalactiae].	27.03	344	217	10	60	399	264	577	1e-16	92.8
rs:WP_019773981	DNA topoisomerase I [Streptococcus sobrinus].	23.65	427	250	14	50	452	254	628	1e-16	92.8
rs:WP_005581320	DNA topoisomerase I [Natronobacterium gregoryi].	23.51	404	263	13	60	454	267	633	1e-16	93.2
rs:WP_012980200	DNA topoisomerase I [Methanocaldococcus sp. FS406-22].	29.76	289	149	12	188	459	599	850	1e-16	93.2
rs:WP_041421399	DNA topoisomerase I [Neisseria gonorrhoeae].	24.22	483	261	14	43	454	228	676	1e-16	93.2
rs:WP_014799952	DNA topoisomerase I [Corynebacterium pseudotuberculosis].	26.15	371	227	11	31	384	249	589	1e-16	93.2
rs:WP_004659079	DNA topoisomerase I [Acinetobacter sp. NIPH 236].	27.10	321	194	10	40	356	267	551	1e-16	93.2
rs:WP_003290000	topoisomerase I [Pseudomonas stutzeri].	25.37	402	244	13	68	452	273	635	1e-16	93.2
rs:WP_016174777	DNA topoisomerase 1 [Enterococcus saccharolyticus].	24.89	446	271	18	34	457	211	614	1e-16	92.8
rs:WP_015050175	DNA topoisomerase I [Thermacetogenium phaeum].	25.93	486	283	17	1	455	170	609	1e-16	92.8
rs:XP_004716390	PREDICTED: DNA topoisomerase 3-beta-1 [Echinops telfairi].	23.58	441	257	16	40	453	263	650	1e-16	93.2
rs:WP_003754393	DNA topoisomerase I [Neisseria polysaccharea].	24.22	483	261	14	43	454	228	676	1e-16	93.2
rs:XP_005808881	PREDICTED: DNA topoisomerase 3-alpha-like [Xiphophorus maculatus].	24.65	434	240	14	60	455	325	709	1e-16	93.2
tr:W7BT11_LISGR	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EUJ27820.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EUJ27820.1};	27.48	302	178	11	166	457	22	292	1e-16	91.3
rs:WP_018699100	hypothetical protein [Amorphus coralli].	26.79	418	238	15	68	452	252	634	1e-16	93.2
rs:WP_002331854	DNA topoisomerase 1 [Enterococcus faecium].	24.55	448	270	14	34	457	211	614	1e-16	92.8
rs:WP_024592543	DNA topoisomerase I [Pseudoalteromonas haloplanktis].	26.63	368	222	12	42	395	257	590	1e-16	93.2
rs:WP_007582594	topoisomerase I [Pseudoalteromonas sp. BSi20429].	26.63	368	222	12	42	395	257	590	1e-16	93.2
rs:WP_036301768	DNA topoisomerase I [Microbacterium sp. C448].	29.50	322	174	12	48	356	271	552	1e-16	93.2
rs:WP_043044512	DNA topoisomerase 1 [Staphylococcus aureus].	24.48	429	255	18	47	452	224	606	1e-16	92.8
rs:WP_008303258	topoisomerase I [Acinetobacter sp. HA].	26.46	427	257	19	40	452	268	651	1e-16	93.2
rs:WP_013833968	DNA topoisomerase I [Novosphingobium sp. PP1Y].	26.90	435	257	14	41	452	222	618	1e-16	93.2
rs:WP_005236830	DNA topoisomerase I [Enterococcus casseliflavus].	23.67	414	261	14	61	457	239	614	1e-16	92.8
rs:WP_002320952	DNA topoisomerase I [Enterococcus faecium].	24.55	448	270	14	34	457	229	632	1e-16	92.8
rs:WP_028052717	DNA topoisomerase I [Carboxydothermus ferrireducens].	25.00	428	260	13	47	454	223	609	1e-16	92.8
rs:WP_046560792	DNA topoisomerase I [Kangiella geojedonensis].	25.26	380	239	11	54	425	272	614	1e-16	93.2
rs:WP_033985421	DNA topoisomerase I [Pseudomonas aeruginosa].	25.55	411	241	14	74	459	260	630	1e-16	92.8
rs:WP_011252816	DNA topoisomerase I [Gluconobacter oxydans].	25.58	430	257	16	54	452	238	635	1e-16	93.2
rs:WP_024599386	DNA topoisomerase I [Pseudoalteromonas haloplanktis].	26.63	368	222	12	42	395	257	590	1e-16	93.2
rs:WP_037326601	DNA topoisomerase I [Anaerococcus lactolyticus].	24.14	406	242	13	67	452	243	602	1e-16	92.8
rs:WP_039163689	DNA topoisomerase I [Leisingera sp. ANG-M1].	25.87	460	258	18	41	454	225	647	1e-16	93.2
rs:WP_003686257	DNA topoisomerase I [Neisseria flavescens].	24.12	481	264	12	43	454	228	676	1e-16	92.8
rs:WP_014558563	DNA topoisomerase I [Corynebacterium pseudotuberculosis].	26.15	371	227	11	31	384	249	589	1e-16	93.2
rs:WP_029238067	DNA topoisomerase I [Streptococcus sobrinus].	23.30	442	266	13	34	452	237	628	1e-16	92.8
tr:J4SSP4_PASMD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	36.73	98	62	0	36	133	15	112	1e-16	86.3
rs:WP_005035632	MULTISPECIES: topoisomerase I [Acinetobacter].	26.69	356	214	12	40	384	268	587	1e-16	93.2
rs:XP_008556752	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Microplitis demolitor].	24.76	416	254	11	60	452	278	657	1e-16	93.2
rs:WP_037000362	DNA topoisomerase I [Pseudomonas pseudoalcaligenes].	26.21	412	249	15	47	446	257	625	1e-16	93.2
rs:WP_009470741	topoisomerase I [gamma proteobacterium HIMB55].	27.70	426	243	17	47	452	263	643	1e-16	93.2
rs:WP_029236761	DNA topoisomerase I [Streptococcus sobrinus].	23.30	442	266	13	34	452	237	628	1e-16	92.8
rs:WP_023614906	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.94	425	254	18	50	452	227	608	1e-16	92.8
rs:WP_021743820	DNA topoisomerase I [Leptotrichia sp. oral taxon 879].	28.06	335	182	12	65	379	237	532	1e-16	92.8
rs:WP_016613225	DNA topoisomerase I [Enterococcus faecium].	23.67	414	261	14	61	457	239	614	1e-16	92.8
rs:WP_033073131	DNA topoisomerase I [Sphingopyxis sp. MWB1].	26.43	420	252	14	54	452	235	618	1e-16	93.2
rs:WP_008166223	topoisomerase I [Pseudoalteromonas sp. BSi20652].	26.63	368	222	12	42	395	257	590	1e-16	93.2
rs:WP_033680386	DNA topoisomerase I [Streptococcus mitis].	23.96	409	238	14	66	452	254	611	1e-16	92.8
rs:WP_005162646	DNA topoisomerase I [Acinetobacter sp. NIPH 284].	26.76	426	257	18	40	452	267	650	1e-16	93.2
rs:WP_008379664	DNA topoisomerase I [Enterococcus sp. C1].	23.67	414	261	14	61	457	239	614	1e-16	92.8
rs:WP_005280639	DNA topoisomerase I [Acinetobacter sp. NIPH 3623].	27.41	321	193	10	40	356	267	551	1e-16	93.2
rs:WP_020256365	hypothetical protein [Candidatus Paceibacter normanii].	24.76	416	256	13	47	452	253	621	1e-16	92.8
rs:WP_016483699	DNA topoisomerase I [Chthonomonas calidirosea].	24.94	437	256	18	45	451	224	618	1e-16	92.8
rs:WP_045548636	DNA topoisomerase I [Nocardioides luteus].	28.45	355	200	14	42	377	255	574	1e-16	93.2
rs:WP_002237530	DNA topoisomerase I [Neisseria meningitidis].	24.22	483	261	14	43	454	228	676	1e-16	92.8
rs:XP_003279918	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Nomascus leucogenys].	25.11	438	261	14	40	450	289	686	1e-16	93.2
rs:WP_022211946	DNA topoisomerase III-like protein, partial [Clostridium sp. CAG:265].	29.55	264	153	9	203	452	2	246	1e-16	90.1
rs:WP_013569613	DNA topoisomerase [Terriglobus saanensis].	24.78	452	254	16	41	450	232	639	1e-16	93.2
rs:WP_045171440	DNA topoisomerase I [Ehrlichia mineirensis].	25.57	438	256	13	47	452	232	631	1e-16	92.8
rs:WP_028545144	DNA topoisomerase I [Paenibacillus taiwanensis].	25.06	431	257	17	50	457	227	614	1e-16	92.8
rs:WP_042237164	DNA topoisomerase I [Paenibacillus sp. FSL R5-0912].	25.90	417	240	16	66	457	242	614	1e-16	92.8
rs:WP_037622473	DNA topoisomerase [Streptococcus sp. 2_1_36FAA].	26.57	350	215	12	61	402	265	580	1e-16	92.4
rs:WP_029052236	DNA topoisomerase I, partial [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	1e-16	92.8
tr:V5RV70_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.79	418	248	19	52	454	231	605	1e-16	92.8
rs:WP_019321618	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	1e-16	92.8
rs:WP_032460103	DNA topoisomerase I [Streptococcus pyogenes].	22.99	422	259	14	50	452	250	624	1e-16	92.8
rs:WP_015335647	DNA topoisomerase 1 [Desulfovibrio hydrothermalis].	25.00	420	255	13	47	450	225	600	1e-16	92.8
rs:WP_046308328	hypothetical protein [Lactobacillus apis].	21.74	460	313	14	24	450	234	679	1e-16	92.8
rs:WP_002275215	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	1e-16	92.8
rs:XP_003877019	putative DNA topoisomerase III [Leishmania mexicana MHOM/GT/2001/U1103].	23.74	417	260	12	39	434	252	631	1e-16	92.8
rs:WP_028294382	DNA topoisomerase I [Oceanobacter kriegii].	25.76	427	261	15	38	452	256	638	1e-16	92.8
tr:D0RWS4_9STRE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.57	350	215	12	61	402	306	621	1e-16	92.8
tr:A0A0E3YI41_CORPS	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:AKC72982.1};	26.15	371	227	11	31	384	239	579	1e-16	93.2
rs:WP_010555034	topoisomerase I [Pseudoalteromonas arctica].	26.63	368	222	12	42	395	257	590	1e-16	92.8
rs:WP_034979206	DNA topoisomerase I [Lactobacillus sp. wkB10].	25.44	401	238	14	70	452	256	613	1e-16	92.8
rs:WP_002288411	MULTISPECIES: DNA topoisomerase I [Enterococcus].	24.55	448	270	14	34	457	211	614	1e-16	92.8
rs:WP_002339402	DNA topoisomerase 1 [Enterococcus faecium].	24.55	448	270	14	34	457	211	614	1e-16	92.8
gpu:CP011214_544	topoisomerase I protein [Microgenomates (Woesebacteria) bacterium GW2011_GWF1_31_35]	25.73	447	267	16	22	452	187	584	1e-16	92.8
tr:A0A076GWJ3_ENTFC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.25	404	235	13	77	457	273	632	1e-16	92.8
rs:WP_032058555	DNA topoisomerase I [Acinetobacter baumannii].	26.44	416	254	17	40	446	266	638	1e-16	92.8
rs:WP_002309563	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	1e-16	92.8
rs:WP_021265626	DNA topoisomerase I [Salmonella enterica].	24.21	413	245	13	61	455	231	593	1e-16	92.8
rs:WP_010730456	DNA topoisomerase 1 [Enterococcus faecium].	24.55	448	270	14	34	457	211	614	1e-16	92.8
rs:WP_007476321	DNA topoisomerase I [Listeria fleischmannii].	23.71	426	268	14	50	457	227	613	1e-16	92.8
rs:WP_002327967	DNA topoisomerase 1 [Enterococcus faecium].	24.55	448	270	14	34	457	211	614	1e-16	92.8
rs:WP_018285616	hypothetical protein [zeta proteobacterium SCGC AB-133-C04].	26.46	427	248	16	52	454	233	617	1e-16	92.8
rs:WP_002256289	DNA topoisomerase I [Neisseria meningitidis].	24.22	483	261	14	43	454	228	676	1e-16	92.8
rs:WP_002232259	DNA topoisomerase I [Neisseria meningitidis].	24.22	483	261	14	43	454	228	676	1e-16	92.8
rs:WP_024782601	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	1e-16	92.8
rs:WP_043933337	DNA topoisomerase I [Bacillus sp. EB01].	23.70	422	263	14	50	452	227	608	1e-16	92.8
rs:WP_027104711	DNA topoisomerase I [Lachnospiraceae bacterium V9D3004].	23.46	456	285	14	18	454	200	610	1e-16	92.8
rs:WP_044131834	DNA topoisomerase I, partial [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	1e-16	92.8
rs:WP_004828589	DNA topoisomerase I [Anaerococcus lactolyticus].	24.14	406	242	13	67	452	243	602	1e-16	92.8
rs:WP_022027298	DNA topoisomerase [Dialister invisus CAG:218].	25.28	439	264	16	38	454	245	641	1e-16	92.8
rs:WP_012824940	DNA topoisomerase I [Halothiobacillus neapolitanus].	27.54	334	198	11	60	377	251	556	1e-16	92.8
rs:XP_008556751	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Microplitis demolitor].	23.89	452	279	12	30	452	287	702	1e-16	93.2
rs:WP_018704265	hypothetical protein [Anaeromusa acidaminophila].	24.17	422	249	14	61	457	240	615	1e-16	92.8
rs:WP_022222304	DNA topoisomerase [Firmicutes bacterium CAG:170].	25.93	432	252	14	47	454	228	615	1e-16	92.8
rs:WP_048178264	DNA topoisomerase [Methanosarcina sp. MTP4].	26.80	388	229	15	86	454	291	642	1e-16	92.8
rs:WP_045807821	DNA topoisomerase I [Lactobacillus spicheri].	25.69	436	256	15	43	457	237	625	1e-16	92.8
rs:WP_019160968	DNA topoisomerase I [Ruminococcus sp. JC304].	24.37	439	273	13	34	454	212	609	1e-16	92.8
rs:WP_035307621	DNA topoisomerase I [Clostridium sp. HMP27].	25.44	401	237	13	74	454	252	610	1e-16	92.8
rs:WP_026666020	DNA topoisomerase I [Butyrivibrio sp. FC2001].	24.06	424	265	13	48	454	232	615	1e-16	92.8
rs:WP_000259046	DNA topoisomerase III [Streptococcus agalactiae].	25.81	372	241	11	18	385	223	563	1e-16	92.4
rs:WP_012032416	DNA topoisomerase I [Pelotomaculum thermopropionicum].	25.29	427	263	14	50	457	228	617	1e-16	92.8
rs:WP_045655781	DNA topoisomerase I [Hyphomonadaceae bacterium BRH_c29].	24.70	421	254	11	60	452	244	629	1e-16	92.8
rs:WP_002259562	DNA topoisomerase I [Neisseria meningitidis].	24.02	483	262	14	43	454	228	676	1e-16	92.8
rs:WP_002216226	DNA topoisomerase I [Neisseria meningitidis].	24.22	483	261	14	43	454	228	676	1e-16	92.8
rs:WP_035153311	DNA topoisomerase I [Calothrix sp. 336/3].	25.49	357	225	9	41	387	257	582	1e-16	92.8
rs:WP_015505597	DNA topoisomerase I [Erwinia amylovora].	24.21	413	245	13	61	455	231	593	1e-16	92.8
rs:WP_016916640	DNA topoisomerase I [Rickettsia honei].	24.10	444	261	15	41	449	225	627	1e-16	92.8
rs:WP_029741796	DNA topoisomerase I [Enterobacter asburiae].	24.21	413	245	13	61	455	231	593	1e-16	92.8
rs:WP_005637796	topoisomerase I [Haemophilus haemolyticus].	26.12	379	231	14	77	446	290	628	1e-16	92.8
rs:WP_041111666	DNA topoisomerase I [Gluconobacter oxydans].	25.47	424	253	16	60	452	244	635	1e-16	92.8
rs:WP_027937588	DNA topoisomerase I [Anaeroarcus burkinensis].	24.17	422	249	14	61	457	240	615	1e-16	92.8
rs:WP_039411736	DNA topoisomerase I [Microbacterium hominis].	29.35	402	212	18	23	392	234	595	1e-16	92.8
rs:XP_012708409	PREDICTED: DNA topoisomerase 3-alpha [Fundulus heteroclitus].	25.12	426	251	14	60	456	323	709	1e-16	92.8
rs:WP_005315206	DNA topoisomerase I [Acinetobacter sp. ANC 3880].	26.53	426	258	18	40	452	267	650	1e-16	92.8
rs:WP_009177887	DNA topoisomerase I [Silicibacter sp. TrichCH4B].	26.51	464	250	19	41	454	225	647	1e-16	92.8
rs:WP_002959733	topoisomerase I [Pseudoalteromonas haloplanktis].	26.63	368	222	12	42	395	257	590	1e-16	92.8
rs:NP_001006181	DNA topoisomerase 3-beta-1 [Gallus gallus].	24.72	441	254	16	25	434	247	640	1e-16	92.8
rs:WP_008534745	DNA topoisomerase I [Streptococcus sp. C150].	24.04	441	263	15	34	452	238	628	1e-16	92.8
rs:WP_034588384	hypothetical protein [Clostridiales bacterium VE202-15].	37.59	141	82	4	257	392	2	141	1e-16	87.8
rs:XP_003279919	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Nomascus leucogenys].	25.11	438	261	14	40	450	194	591	1e-16	92.8
rs:XP_005007385	PREDICTED: DNA topoisomerase 3-beta-1 [Cavia porcellus].	23.81	441	256	16	40	453	263	650	1e-16	92.8
rs:WP_041981298	DNA topoisomerase I [Streptococcus agalactiae].	22.65	437	275	14	34	452	229	620	1e-16	92.8
rs:WP_022214408	DNA topoisomerase [Blautia sp. CAG:237].	24.31	436	277	11	34	454	212	609	1e-16	92.8
rs:WP_047952547	DNA topoisomerase I, partial [Neisseria gonorrhoeae].	23.81	483	264	13	41	452	225	674	1e-16	92.4
rs:WP_006275002	DNA topoisomerase I [Asticcacaulis biprosthecium].	26.12	402	227	13	86	454	268	632	1e-16	92.8
rs:WP_005255320	DNA topoisomerase I [Acinetobacter sp. NIPH 2168].	27.10	321	194	10	40	356	267	551	1e-16	92.8
rs:WP_009082009	DNA topoisomerase I [Peptostreptococcaceae bacterium AS15].	23.52	438	261	12	43	457	220	606	1e-16	92.4
rs:WP_023425866	DNA topoisomerase I, archaeal [uncultured Acidilobus sp. CIS].	28.21	397	231	14	45	425	255	613	1e-16	92.4
rs:WP_004613890	hypothetical protein, partial [Tyzzerella nexilis].	32.43	185	115	6	219	395	1	183	1e-16	88.6
rs:WP_046294178	DNA topoisomerase I [Mycobacterium sp. UM_Kg17].	27.09	358	211	11	38	377	268	593	1e-16	92.8
rs:WP_022292352	DNA topoisomerase [Staphylococcus sp. CAG:324].	24.95	477	267	18	35	453	216	659	1e-16	92.8
rs:WP_006783782	DNA topoisomerase I [Turicibacter sanguinis].	24.15	443	247	12	58	449	236	640	1e-16	92.4
rs:WP_011358785	DNA topoisomerase I [Pelodictyon luteolum].	26.80	444	255	16	41	454	229	632	1e-16	92.8
rs:WP_019532523	DNA topoisomerase I [Paenibacillus ginsengihumi].	25.23	436	259	16	47	457	223	616	1e-16	92.8
rs:WP_047951091	DNA topoisomerase I, partial [Neisseria gonorrhoeae].	23.81	483	264	13	41	452	225	674	1e-16	92.4
rs:XP_005875637	PREDICTED: DNA topoisomerase 3-beta-1 [Myotis brandtii].	23.58	441	257	16	40	453	263	650	1e-16	92.8
rs:XP_009076161	PREDICTED: DNA topoisomerase 3-beta-1 [Acanthisitta chloris].	24.88	422	246	14	40	434	263	640	1e-16	92.8
rs:WP_006729968	DNA topoisomerase I [Lactobacillus iners].	22.71	480	299	17	1	452	175	610	1e-16	92.4
tr:A0A091SZH1_9AVES	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.43	438	259	15	25	434	224	617	1e-16	92.8
rs:WP_016475614	DNA topoisomerase I [Veillonella sp. HPA0037].	24.37	476	300	16	1	454	233	670	1e-16	92.8
rs:WP_033027589	DNA topoisomerase III, partial [Geobacillus sp. MAS1].	29.41	204	139	4	36	236	245	446	1e-16	91.7
rs:WP_028762074	DNA topoisomerase I [Shewanella colwelliana].	26.39	379	231	11	77	446	292	631	1e-16	92.8
rs:WP_031877302	DNA topoisomerase III, partial [Staphylococcus aureus].	29.70	202	132	5	251	450	1	194	1e-16	89.7
rs:WP_043025818	DNA topoisomerase I [Streptococcus equi].	23.75	459	273	14	19	452	219	625	1e-16	92.8
rs:WP_022679588	DNA topoisomerase I [Sandarakinorhabdus limnophila].	26.21	435	266	15	42	454	224	625	1e-16	92.8
rs:XP_006901251	PREDICTED: DNA topoisomerase 3-alpha [Elephantulus edwardii].	25.28	443	268	16	40	456	264	669	1e-16	92.8
rs:WP_026443392	DNA topoisomerase [Acidobacterium sp. PMMR2].	25.23	436	253	18	41	446	230	622	1e-16	92.8
rs:WP_010727828	DNA topoisomerase 1 [Enterococcus faecium].	24.67	450	267	16	34	457	211	614	1e-16	92.4
rs:WP_029485243	DNA topoisomerase I [Enterococcus faecium].	24.55	448	270	14	34	457	211	614	1e-16	92.4
rs:WP_021919504	DNA topoisomerase [Firmicutes bacterium CAG:114].	27.97	429	246	18	48	454	229	616	1e-16	92.8
tr:A0A068UAG3_COFCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.32	466	273	17	22	452	258	683	1e-16	92.8
rs:XP_007939652	PREDICTED: DNA topoisomerase 3-alpha [Orycteropus afer afer].	25.71	455	251	16	40	456	289	694	1e-16	92.8
tr:A0A091NQJ5_APAVI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.66	438	258	15	25	434	224	617	1e-16	92.8
tr:A0A091RQY5_NESNO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.43	438	259	15	25	434	224	617	1e-16	92.8
rs:WP_022491918	DNA topoisomerase [Clostridium sp. CAG:813].	23.10	394	249	13	77	452	130	487	1e-16	92.4
rs:WP_041406645	DNA topoisomerase I [Shewanella loihica].	26.63	353	216	9	42	384	257	576	1e-16	92.8
rs:WP_009121355	DNA topoisomerase III [Bacteroides clarus].	24.17	393	242	12	21	394	220	575	1e-16	92.4
rs:WP_005938434	DNA topoisomerase I [Gordonia hirsuta].	27.40	354	214	12	41	379	262	587	1e-16	92.8
rs:XP_009872449	PREDICTED: DNA topoisomerase 3-beta-1, partial [Apaloderma vittatum].	24.66	438	258	15	25	434	238	631	1e-16	92.8
tr:W3Z2X6_9FUSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.72	449	287	17	24	452	207	624	1e-16	92.4
rs:WP_023423913	DNA topoisomerase I, archaeal [uncultured Acidilobus sp. MG].	28.46	397	230	14	45	425	242	600	1e-16	92.4
rs:XP_005054966	PREDICTED: DNA topoisomerase 3-beta-1 [Ficedula albicollis].	24.66	438	258	15	25	434	247	640	1e-16	92.8
rs:WP_034078458	DNA topoisomerase I [Pseudomonas aeruginosa].	25.58	391	240	12	68	446	274	625	1e-16	92.8
rs:WP_021978486	DNA topoisomerase [Clostridium sp. CAG:793].	24.71	425	262	13	50	454	227	613	1e-16	92.4
rs:WP_046189722	DNA topoisomerase I [Mycobacterium arupense].	27.09	358	211	11	38	377	268	593	1e-16	92.8
tr:A0A097ART4_THEKI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	492	282	20	1	454	170	612	1e-16	92.4
rs:WP_003705339	DNA topoisomerase I [Neisseria gonorrhoeae].	24.22	483	261	14	43	454	228	676	1e-16	92.8
rs:WP_025986837	DNA topoisomerase I [Pseudomonas aeruginosa].	25.55	411	241	14	74	459	260	630	1e-16	92.4
tr:A0A091C304_9ENTE	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KFN91095.1}; EC=5.99.1.- {ECO:0000313|EMBL:KFN91095.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KFN91095.1};	28.23	248	145	7	214	457	43	261	1e-16	90.1
rs:WP_009514124	DNA topoisomerase I [Acinetobacter sp. WC-323].	27.41	321	193	10	40	356	267	551	1e-16	92.8
rs:WP_028759719	DNA topoisomerase I [Shewanella putrefaciens].	26.18	424	259	15	35	446	250	631	1e-16	92.8
tr:A3QF42_SHELP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.63	353	216	9	42	384	273	592	1e-16	92.8
rs:WP_001548566	DNA topoisomerase I [Staphylococcus aureus].	24.48	429	255	18	47	452	226	608	1e-16	92.4
rs:WP_007251279	topoisomerase I [Pseudomonas syringae group genomosp. 3].	26.76	411	248	15	47	446	259	627	1e-16	92.8
rs:WP_032840587	DNA topoisomerase [Fusobacterium sp. CM21].	24.72	449	287	17	24	452	211	628	1e-16	92.4
rs:WP_034574126	DNA topoisomerase I [Mageeibacillus indolicus].	25.22	452	274	14	23	452	203	612	1e-16	92.4
rs:WP_003776900	DNA topoisomerase I [Alloiococcus otitis].	25.74	404	245	13	69	457	248	611	1e-16	92.4
rs:WP_043032798	hypothetical protein [Clostridium botulinum].	24.74	287	190	7	77	357	282	548	1e-16	92.8
rs:WP_031921185	DNA topoisomerase 1 [Staphylococcus aureus].	24.48	429	255	18	47	452	224	606	1e-16	92.4
rs:WP_005220842	DNA topoisomerase I [Acinetobacter sp. CIP 101934].	26.46	427	257	19	40	452	268	651	1e-16	92.8
rs:WP_005051290	DNA topoisomerase I [Acinetobacter beijerinckii].	27.10	321	194	10	40	356	267	551	1e-16	92.8
rs:WP_028531204	MULTISPECIES: DNA topoisomerase I [Paenibacillus].	23.25	443	281	14	35	457	211	614	1e-16	92.4
rs:WP_004182436	DNA topoisomerase I [Streptococcus salivarius].	24.04	441	263	15	34	452	238	628	1e-16	92.4
rs:WP_036983237	DNA topoisomerase I [Providencia alcalifaciens].	24.21	413	245	12	61	455	231	593	1e-16	92.4
rs:WP_039489912	MULTISPECIES: DNA topoisomerase I [Pseudoalteromonas].	26.63	368	222	12	42	395	257	590	1e-16	92.8
rs:WP_031872092	DNA topoisomerase I [Staphylococcus aureus].	24.48	429	255	18	47	452	224	606	1e-16	92.4
rs:WP_016352460	DNA topoisomerase I [Spiribacter salinus].	28.81	361	207	13	35	377	239	567	1e-16	92.8
tr:T0TYN3_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.04	441	263	15	34	452	153	543	1e-16	92.4
tr:W5E6N9_WHEAT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.28	449	252	18	39	452	235	639	1e-16	92.4
rs:WP_028700188	DNA topoisomerase I [Pseudomonas monteilii].	26.52	396	237	15	77	454	263	622	1e-16	92.4
rs:XP_006099574	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Myotis lucifugus].	23.58	441	257	16	40	453	263	650	1e-16	92.8
rs:WP_015955838	DNA topoisomerase I [Cyanothece sp. PCC 7424].	25.33	458	254	20	29	450	224	629	1e-16	92.4
sp:TOP1_STAA3	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.48	429	255	18	47	452	224	606	1e-16	92.4
rs:WP_024370092	MULTISPECIES: DNA topoisomerase I [Exiguobacterium].	23.95	430	270	11	45	454	222	614	1e-16	92.4
rs:WP_044275446	DNA topoisomerase I [Pseudomonas fluorescens].	24.94	401	259	12	70	459	256	625	1e-16	92.4
rs:WP_022657618	DNA topoisomerase I [Desulfovibrio desulfuricans].	23.89	427	265	11	43	452	221	604	1e-16	92.4
rs:WP_003106911	DNA topoisomerase I [Streptococcus parauberis].	22.95	440	270	14	34	452	234	625	1e-16	92.4
rs:WP_013448201	DNA topoisomerase I [Neisseria lactamica].	24.22	483	261	14	43	454	228	676	1e-16	92.4
rs:WP_007786297	DNA topoisomerase I [Desulfosporosinus youngiae].	25.00	424	266	11	48	454	225	613	1e-16	92.4
rs:XP_008413798	PREDICTED: DNA topoisomerase 3-alpha [Poecilia reticulata].	24.48	433	243	12	60	455	321	706	1e-16	92.8
tr:T1J1V7_STRMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.77	436	264	13	40	450	261	657	1e-16	92.8
rs:WP_024603564	DNA topoisomerase I, partial [Pseudoalteromonas haloplanktis].	26.84	354	214	11	42	384	257	576	1e-16	92.4
rs:WP_004352838	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	25.55	411	241	14	74	459	260	630	1e-16	92.4
rs:WP_014967754	DNA topoisomerase I [Gottschalkia acidurici].	22.78	439	284	10	34	457	214	612	1e-16	92.4
rs:WP_031925401	DNA topoisomerase 1 [Staphylococcus aureus].	24.48	429	255	18	47	452	224	606	1e-16	92.4
rs:WP_031913953	DNA topoisomerase I [Staphylococcus aureus].	24.71	429	254	18	47	452	224	606	1e-16	92.4
rs:WP_031793687	DNA topoisomerase I [Staphylococcus aureus].	24.48	429	255	18	47	452	224	606	1e-16	92.4
rs:WP_011609067	topoisomerase I [Histophilus somni].	26.70	382	225	15	77	446	290	628	1e-16	92.8
rs:WP_028536783	DNA topoisomerase I [Paludibacterium yongneupense].	25.75	431	256	14	43	452	227	614	1e-16	92.4
rs:WP_038398842	DNA topoisomerase I [Enterococcus faecium].	25.25	404	235	13	77	457	255	614	1e-16	92.4
rs:XP_002428087	DNA topoisomerase 3-alpha, putative [Pediculus humanus corporis].	26.32	437	252	16	39	449	256	648	1e-16	92.8
rs:WP_040958459	DNA topoisomerase I [Sinorhizobium fredii].	25.34	438	266	13	47	452	230	638	1e-16	92.8
rs:WP_029377477	DNA topoisomerase I [Staphylococcus xylosus].	25.06	395	234	14	77	452	254	605	1e-16	92.4
rs:WP_017647390	DNA topoisomerase I [Streptococcus agalactiae].	22.43	437	276	13	34	452	229	620	1e-16	92.4
rs:XP_009329019	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Pygoscelis adeliae].	24.43	438	259	15	25	434	111	504	1e-16	92.4
rs:WP_029635180	DNA topoisomerase I [[Scytonema hofmanni] UTEX B 1581].	25.54	372	229	10	41	395	249	589	1e-16	92.8
rs:WP_035383427	DNA topoisomerase I, partial [Ferriphaselus sp. R-1].	24.42	471	286	16	3	452	195	616	1e-16	92.4
rs:XP_005445283	PREDICTED: DNA topoisomerase 3-beta-1 [Falco cherrug].	24.51	457	264	17	25	453	247	650	1e-16	92.8
rs:WP_003438266	DNA topoisomerase I [Peptoclostridium difficile].	21.79	436	282	10	36	454	215	608	1e-16	92.4
tr:W1Y7F5_9ZZZZ	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ETJ37625.1}; Flags: Fragment;	48.31	89	46	0	277	365	2	90	2e-16	85.5
rs:WP_000774784	DNA topoisomerase 1 [Staphylococcus aureus].	24.48	429	255	18	47	452	224	606	2e-16	92.4
rs:WP_024596730	DNA topoisomerase I, partial [Pseudoalteromonas haloplanktis].	26.84	354	214	11	42	384	257	576	2e-16	92.4
tr:S9SZJ9_PAEAL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.25	443	281	14	35	457	185	588	2e-16	92.4
rs:WP_022619737	DNA topoisomerase I [Peptoclostridium difficile].	21.79	436	282	10	36	454	215	608	2e-16	92.4
rs:WP_013919504	DNA topoisomerase I [Paenibacillus mucilaginosus].	24.65	434	264	14	47	457	224	617	2e-16	92.4
rs:WP_006787029	DNA topoisomerase I [Thiorhodospira sibirica].	28.40	324	180	13	45	350	233	522	2e-16	92.4
rs:WP_008858871	DNA topoisomerase I [Dialister succinatiphilus].	23.49	430	265	13	47	454	257	644	2e-16	92.4
rs:WP_013990513	DNA topoisomerase I [Streptococcus salivarius].	24.04	441	263	15	34	452	238	628	2e-16	92.4
gp:CP001996_1224	DNA topoisomerase I [Staphylococcus aureus subsp. aureus ED133]	24.48	429	255	18	47	452	226	608	2e-16	92.4
rs:XP_010160349	PREDICTED: DNA topoisomerase 3-beta-1 [Caprimulgus carolinensis].	24.43	438	259	15	25	434	247	640	2e-16	92.4
rs:WP_009892959	DNA topoisomerase I [Peptoclostridium difficile].	21.79	436	282	10	36	454	215	608	2e-16	92.4
rs:WP_019785014	DNA topoisomerase I [Streptococcus sobrinus].	23.65	444	262	15	34	452	237	628	2e-16	92.4
tr:D1NG17_HAEIF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	44.32	88	49	0	36	123	211	298	2e-16	89.7
rs:WP_041999769	DNA topoisomerase I [Aeromonas bivalvium].	27.08	432	257	17	37	452	247	636	2e-16	92.4
rs:WP_024783829	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	2e-16	92.4
rs:WP_008793675	DNA topoisomerase I [Fusobacterium periodonticum].	26.59	331	196	8	61	377	240	537	2e-16	92.4
rs:WP_018225554	DNA topoisomerase I [actinobacterium SCGC AAA044-N04].	28.31	325	194	10	41	354	254	550	2e-16	92.8
rs:WP_002298115	DNA topoisomerase I [Enterococcus faecium].	24.55	448	270	14	34	457	211	614	2e-16	92.4
rs:WP_008385546	DNA topoisomerase I [Rhodovulum sp. PH10].	25.62	445	261	18	45	454	229	638	2e-16	92.8
rs:WP_038344890	DNA topoisomerase I [Acinetobacter sp. A47].	26.76	426	257	18	40	452	267	650	2e-16	92.4
rs:WP_004899308	DNA topoisomerase I [Acinetobacter brisouii].	26.70	427	256	18	40	452	268	651	2e-16	92.4
rs:XP_009487010	PREDICTED: DNA topoisomerase 3-beta-1 [Pelecanus crispus].	24.43	438	259	15	25	434	247	640	2e-16	92.4
rs:WP_002349050	hypothetical protein, partial [Enterococcus faecium].	35.26	156	92	3	210	365	1	147	2e-16	88.6
rs:WP_002230188	DNA topoisomerase I [Neisseria meningitidis].	24.02	483	262	14	43	454	228	676	2e-16	92.4
rs:WP_038464132	DNA topoisomerase I [Candidatus Paracaedibacter acanthamoebae].	24.32	440	265	15	47	454	231	634	2e-16	92.4
tr:K2F398_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.36	427	259	13	47	454	229	610	2e-16	92.4
rs:WP_003108440	DNA topoisomerase I [Streptococcus parauberis].	22.95	440	270	14	34	452	234	625	2e-16	92.4
rs:WP_003297053	DNA topoisomerase I subunit omega [Pseudomonas stutzeri].	24.64	422	268	12	42	452	253	635	2e-16	92.4
rs:WP_024034037	topoisomerase I [Pseudoalteromonas sp. NW 4327].	25.59	422	262	14	36	446	251	631	2e-16	92.4
rs:WP_023161792	DNA topoisomerase [Clostridium autoethanogenum].	24.12	398	264	11	47	427	251	627	2e-16	92.4
rs:WP_017712774	hypothetical protein [Prochlorothrix hollandica].	28.65	349	204	11	41	377	268	583	2e-16	92.4
rs:WP_019643573	hypothetical protein [Novispirillum itersonii].	24.57	464	285	15	24	454	208	639	2e-16	92.4
rs:WP_041008850	DNA topoisomerase I [Mesorhizobium plurifarium].	26.12	448	259	19	41	452	224	635	2e-16	92.4
tr:A0A0A3W6Y3_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.69	356	214	12	40	384	244	563	2e-16	92.4
rs:WP_012850362	DNA topoisomerase I [Edwardsiella tarda].	27.04	429	260	15	41	459	213	598	2e-16	92.4
rs:WP_041152313	DNA topoisomerase I [Lactobacillus kunkeei].	25.68	405	240	15	65	452	259	619	2e-16	92.4
rs:XP_010010011	PREDICTED: DNA topoisomerase 3-beta-1 [Nestor notabilis].	24.43	438	259	15	25	434	247	640	2e-16	92.4
rs:WP_033963813	DNA topoisomerase I [Pseudomonas aeruginosa].	24.46	417	238	14	74	459	260	630	2e-16	92.4
rs:WP_034234041	DNA topoisomerase I [Lachnospiraceae bacterium AC2029].	25.30	411	249	12	61	454	235	604	2e-16	92.4
rs:WP_041511027	DNA topoisomerase I [Shewanella sp. cp20].	27.36	318	188	9	77	384	292	576	2e-16	92.4
rs:WP_034530828	DNA topoisomerase I [Lactobacillus kunkeei].	25.68	405	240	15	65	452	259	619	2e-16	92.4
rs:WP_004890309	DNA topoisomerase I [Acinetobacter schindleri].	26.46	427	257	19	40	452	268	651	2e-16	92.4
rs:WP_009524712	DNA topoisomerase I [Peptostreptococcaceae bacterium ACC19a].	24.81	399	236	11	77	457	254	606	2e-16	92.4
rs:WP_026826260	DNA topoisomerase I [Exiguobacterium marinum].	24.69	405	257	11	66	454	242	614	2e-16	92.4
rs:WP_021424740	DNA topoisomerase [Peptoclostridium difficile].	27.45	306	174	10	66	357	266	537	2e-16	92.4
rs:WP_016621297	DNA topoisomerase I [Enterococcus faecalis].	23.67	414	261	14	61	457	239	614	2e-16	92.4
rs:WP_014371423	DNA topoisomerase I [Paenibacillus mucilaginosus].	24.65	434	265	14	47	457	224	618	2e-16	92.4
rs:WP_009744288	DNA topoisomerase I [Actinomyces sp. oral taxon 178].	27.52	367	218	12	42	385	253	594	2e-16	92.4
rs:WP_037578240	DNA topoisomerase I [Streptococcus equi].	23.80	416	241	13	61	452	262	625	2e-16	92.4
rs:WP_018379577	DNA topoisomerase I [Streptococcus thoraltensis].	23.81	441	265	15	34	452	234	625	2e-16	92.4
rs:WP_033963794	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	25.55	411	241	14	74	459	158	528	2e-16	92.0
rs:WP_022329931	DNA topoisomerase [Firmicutes bacterium CAG:313].	25.33	450	254	15	20	450	220	606	2e-16	92.4
rs:WP_002888489	DNA topoisomerase I [Streptococcus salivarius].	24.04	441	263	15	34	452	238	628	2e-16	92.4
rs:XP_009698988	PREDICTED: DNA topoisomerase 3-beta-1 [Cariama cristata].	24.43	438	259	15	25	434	247	640	2e-16	92.4
rs:WP_032825615	DNA topoisomerase I [Haemophilus haemolyticus].	26.12	379	231	14	77	446	290	628	2e-16	92.4
rs:WP_022364712	DNA topoisomerase [Clostridium sp. CAG:505].	25.63	437	254	20	41	454	238	626	2e-16	92.4
rs:XP_005524443	PREDICTED: DNA topoisomerase 3-beta-1 [Pseudopodoces humilis].	24.43	438	259	15	25	434	247	640	2e-16	92.4
rs:WP_003419396	DNA topoisomerase I [Peptoclostridium difficile].	21.79	436	282	10	36	454	215	608	2e-16	92.4
rs:WP_015898448	DNA topoisomerase [Acidobacterium capsulatum].	25.40	437	251	17	41	446	232	624	2e-16	92.4
rs:WP_004800148	DNA topoisomerase I [Acinetobacter sp. CIP 102637].	26.76	426	257	18	40	452	267	650	2e-16	92.4
rs:WP_048137608	MULTISPECIES: DNA topoisomerase [Methanosarcina].	25.62	441	272	17	34	454	238	642	2e-16	92.4
rs:WP_043040559	DNA topoisomerase I [Streptococcus equi].	23.80	416	241	13	61	452	262	625	2e-16	92.4
rs:WP_041726937	DNA topoisomerase I, partial [Desulfurispirillum indicum].	25.29	435	266	16	36	452	216	609	2e-16	92.0
rs:WP_002287969	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	2e-16	92.4
tr:A0A093J4N4_FULGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.43	438	259	15	25	434	224	617	2e-16	92.4
rs:WP_031844621	DNA topoisomerase I [Staphylococcus aureus].	24.48	429	255	18	47	452	224	606	2e-16	92.4
rs:WP_044677942	DNA topoisomerase [Streptococcus suis].	26.97	330	207	10	60	385	264	563	2e-16	92.0
rs:XP_009665048	PREDICTED: DNA topoisomerase 3-beta-1 [Struthio camelus australis].	24.43	438	259	15	25	434	247	640	2e-16	92.4
rs:WP_014633069	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.04	441	263	15	34	452	238	628	2e-16	92.4
rs:WP_037599980	DNA topoisomerase I [Streptococcus sp. ACS2].	24.04	441	263	15	34	452	238	628	2e-16	92.4
rs:WP_021144079	DNA topoisomerase I [Streptococcus sp. HSISS1].	24.04	441	263	15	34	452	238	628	2e-16	92.4
rs:WP_021404437	DNA topoisomerase I [Peptoclostridium difficile].	21.79	436	282	10	36	454	215	608	2e-16	92.4
rs:WP_020833479	DNA topoisomerase I [Streptococcus pyogenes].	22.99	422	259	14	50	452	250	624	2e-16	92.4
rs:XP_009947595	PREDICTED: DNA topoisomerase 3-beta-1 [Leptosomus discolor].	24.43	438	259	15	25	434	247	640	2e-16	92.4
tr:A0A0A0AQK4_CHAVO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.43	438	259	15	25	434	224	617	2e-16	92.4
rs:WP_034064766	DNA topoisomerase I [Pseudomonas aeruginosa].	25.61	410	242	13	74	459	260	630	2e-16	92.0
tr:A0A0D6N3W7_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.45	440	262	16	46	452	230	636	2e-16	92.4
rs:WP_013581109	DNA topoisomerase [Granulicella tundricola].	25.94	451	261	16	34	450	225	636	2e-16	92.4
rs:WP_039274721	DNA topoisomerase I [Paenibacillus polymyxa].	25.18	413	249	15	65	457	242	614	2e-16	92.4
rs:WP_029516985	DNA topoisomerase I [Paenibacillus polymyxa].	25.18	413	249	15	65	457	242	614	2e-16	92.4
rs:WP_018082189	DNA topoisomerase I [Asticcacaulis benevestitus].	25.58	430	258	12	54	454	237	633	2e-16	92.4
tr:E3D5G6_NEIM7	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.02	483	262	14	43	454	281	729	2e-16	92.4
tr:I4E2V2_NEIME	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.02	483	262	14	43	454	281	729	2e-16	92.4
tr:C6SEJ0_NEIME	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.02	483	262	14	43	454	281	729	2e-16	92.4
rs:XP_006769027	PREDICTED: DNA topoisomerase 3-beta-1 [Myotis davidii].	23.58	441	257	16	40	453	263	650	2e-16	92.4
tr:A0A091VC14_OPIHO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.43	438	259	15	25	434	224	617	2e-16	92.4
rs:WP_019196747	DNA topoisomerase I [Afipia birgiae].	25.57	442	265	14	45	454	228	637	2e-16	92.4
rs:WP_034585104	DNA topoisomerase I [Acinetobacter sp. HR7].	26.69	356	214	12	40	384	268	587	2e-16	92.4
rs:WP_002496234	DNA topoisomerase I [Staphylococcus epidermidis].	23.93	422	260	14	50	452	227	606	2e-16	92.0
sp:TOP1_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.48	429	255	18	47	452	224	606	2e-16	92.0
rs:WP_000259050	DNA topoisomerase III [Streptococcus agalactiae].	26.15	348	215	10	60	399	264	577	2e-16	92.0
rs:WP_021411029	DNA topoisomerase I [Peptoclostridium difficile].	21.79	436	282	10	36	454	215	608	2e-16	92.0
rs:WP_019021654	DNA topoisomerase I [Thioalkalivibrio sp. ALE23].	28.62	304	174	7	61	350	248	522	2e-16	92.4
rs:WP_002349796	hypothetical protein, partial [Enterococcus faecium].	35.26	156	92	3	210	365	1	147	2e-16	88.6
rs:WP_009381719	DNA topoisomerase I [Staphylococcus massiliensis].	23.64	423	262	14	49	452	226	606	2e-16	92.0
tr:D5S2T3_PEPDI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.79	436	282	10	36	454	221	614	2e-16	92.0
rs:WP_029635562	DNA topoisomerase I [actinobacterium SCGC AAA041-L13].	28.31	325	194	10	41	354	254	550	2e-16	92.4
rs:WP_003707115	DNA topoisomerase I [Neisseria lactamica].	23.71	485	266	13	41	454	225	676	2e-16	92.4
rs:WP_002276719	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	2e-16	92.0
rs:WP_031545533	DNA topoisomerase I [Lachnospiraceae bacterium AC2014].	23.58	424	267	11	48	454	227	610	2e-16	92.0
tr:M0WQP3_HORVD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.23	446	256	17	39	452	266	670	2e-16	92.4
rs:WP_015171261	DNA topoisomerase I [Geitlerinema sp. PCC 7407].	27.51	349	208	10	41	377	249	564	2e-16	92.4
tr:F9GJ95_HAEHA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.12	379	231	14	77	446	296	634	2e-16	92.4
rs:XP_011587889	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Aquila chrysaetos canadensis].	24.43	438	259	15	25	434	222	615	2e-16	92.4
rs:WP_030125930	DNA topoisomerase I [Streptococcus pyogenes].	22.99	422	259	14	50	452	250	624	2e-16	92.0
rs:WP_043983542	DNA topoisomerase I [Streptococcus equi].	23.80	416	241	13	61	452	262	625	2e-16	92.0
rs:WP_002239431	DNA topoisomerase I [Neisseria meningitidis].	24.02	483	262	14	43	454	228	676	2e-16	92.4
rs:WP_004813291	DNA topoisomerase I [Acinetobacter schindleri].	26.79	321	195	10	40	356	268	552	2e-16	92.4
tr:A0A091ETB4_CORBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.64	422	247	14	40	434	240	617	2e-16	92.4
rs:WP_044069353	DNA topoisomerase I [Pseudomonas aeruginosa].	25.50	404	250	13	74	459	260	630	2e-16	92.0
rs:WP_038433403	DNA topoisomerase I [Streptococcus pyogenes].	23.22	422	258	14	50	452	250	624	2e-16	92.0
rs:WP_020367886	DNA topoisomerase I, partial [Staphylococcus epidermidis].	23.93	422	260	14	50	452	147	526	2e-16	92.0
tr:C6SJC0_NEIME	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.02	483	262	14	43	454	281	729	2e-16	92.4
rs:WP_037443114	DNA topoisomerase I [Shewanella sp. YQH10].	25.87	402	256	12	51	446	265	630	2e-16	92.4
rs:WP_011744019	DNA topoisomerase I [Chlorobium phaeobacteroides].	27.12	413	239	17	68	454	256	632	2e-16	92.4
rs:WP_021414805	DNA topoisomerase I [Peptoclostridium difficile].	21.79	436	282	10	36	454	215	608	2e-16	92.0
tr:A0A093RLU4_PYGAD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.43	438	259	15	25	434	224	617	2e-16	92.4
rs:WP_002457370	DNA topoisomerase I [Staphylococcus epidermidis].	23.93	422	260	14	50	452	227	606	2e-16	92.0
rs:XP_001686899	putative DNA topoisomerase III [Leishmania major strain Friedlin].	26.79	336	209	7	50	379	263	567	2e-16	92.4
rs:WP_026651296	DNA topoisomerase I [Butyrivibrio proteoclasticus].	25.06	423	262	14	48	454	236	619	2e-16	92.0
rs:WP_005977801	DNA topoisomerase I [Ruegeria lacuscaerulensis].	26.36	459	250	17	47	454	231	652	2e-16	92.4
rs:WP_010649333	DNA topoisomerase I [Oceanobacillus massiliensis].	25.29	427	257	16	52	457	229	614	2e-16	92.0
rs:WP_024603974	DNA topoisomerase I [Pseudoalteromonas haloplanktis].	26.63	368	222	12	42	395	257	590	2e-16	92.4
rs:WP_028713422	DNA topoisomerase I [Paracoccus sp. J55].	25.87	429	257	14	51	454	233	625	2e-16	92.4
rs:WP_016542433	DNA topoisomerase I [Acinetobacter gyllenbergii].	26.76	426	257	18	40	452	267	650	2e-16	92.4
tr:A0A091PQ62_LEPDC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.43	438	259	15	25	434	224	617	2e-16	92.4
rs:WP_000259049	DNA topoisomerase III [Streptococcus agalactiae].	26.15	348	215	10	60	399	264	577	2e-16	92.0
rs:WP_042667972	DNA topoisomerase I [Desulfurococcus amylolyticus].	25.32	391	243	14	47	424	254	608	2e-16	92.0
rs:WP_033973126	DNA topoisomerase I [Pseudomonas aeruginosa].	24.46	417	238	14	74	459	260	630	2e-16	92.0
rs:WP_023093022	DNA topoisomerase I [Pseudomonas aeruginosa].	24.46	417	238	14	74	459	260	630	2e-16	92.0
rs:WP_028303438	DNA topoisomerase I [Oceanospirillum maris].	27.45	408	245	17	48	446	267	632	2e-16	92.4
gp:CP003149_4723	DNA topoisomerase I [Pseudomonas aeruginosa DK2]	24.46	417	238	14	74	459	212	582	2e-16	92.0
rs:XP_011587887	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Aquila chrysaetos canadensis].	24.43	438	259	15	25	434	247	640	2e-16	92.4
tr:E6QCJ7_9ZZZZ	SubName: Full=DNA topoisomerase I, plasmid (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) {ECO:0000313|EMBL:CBI04923.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI04923.1};	29.24	383	220	13	77	445	256	601	2e-16	92.0
sp:TOP1_STAS1	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	22.69	432	272	13	40	452	217	605	2e-16	92.0
tr:D0EG00_LEIDO	SubName: Full=DNA topoisomerase III beta {ECO:0000313|EMBL:ACX31684.1};	23.74	417	260	12	39	434	252	631	2e-16	92.4
rs:XP_010700529	DNA topoisomerase III, putative [Leishmania panamensis].	24.11	419	256	14	39	434	252	631	2e-16	92.4
rs:WP_028243884	DNA topoisomerase I [Pseudobutyrivibrio ruminis].	22.30	435	293	9	36	457	213	615	2e-16	92.0
rs:WP_031685624	DNA topoisomerase I [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	2e-16	92.4
rs:WP_013075487	DNA topoisomerase I [Kyrpidia tusciae].	23.87	444	273	14	36	457	213	613	2e-16	92.0
rs:WP_011539659	DNA topoisomerase I [Ruegeria sp. TM1040].	26.08	464	252	18	41	454	225	647	2e-16	92.4
rs:WP_018677342	topoisomerase I [Acinetobacter tjernbergiae].	26.76	426	257	18	40	452	267	650	2e-16	92.4
rs:WP_031755155	DNA topoisomerase I [Pseudomonas aeruginosa].	24.46	417	238	14	74	459	260	630	2e-16	92.0
rs:WP_026749247	DNA topoisomerase I [Leptotrichia trevisanii].	25.97	362	211	11	36	379	210	532	2e-16	92.4
rs:WP_009526510	DNA topoisomerase I [Peptostreptococcaceae bacterium CM2].	24.81	399	236	11	77	457	254	606	2e-16	92.0
tr:A0A023GLY9_9ACAR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.65	394	231	12	40	414	299	653	2e-16	92.0
rs:WP_036593777	DNA topoisomerase I, partial [Paenibacillus sophorae].	27.20	375	209	14	1	354	220	551	2e-16	92.4
tr:A0A093H5H3_STRCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.43	438	259	15	25	434	224	617	2e-16	92.4
rs:WP_000259055	DNA topoisomerase III [Streptococcus agalactiae].	26.48	355	214	11	43	385	244	563	2e-16	92.0
rs:WP_009531537	DNA topoisomerase I [Peptostreptococcaceae bacterium OBRC8].	24.81	399	236	11	77	457	254	606	2e-16	92.0
rs:WP_038649991	DNA topoisomerase I [Roseibacterium elongatum].	27.95	483	240	22	41	454	225	668	2e-16	92.4
tr:E0QIP1_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.52	438	261	12	43	457	223	609	2e-16	92.0
rs:WP_010019870	DNA topoisomerase I [Lactobacillus farciminis].	24.88	430	265	14	46	457	228	617	2e-16	92.0
rs:WP_003703296	DNA topoisomerase I [Neisseria gonorrhoeae].	23.92	485	265	13	41	454	225	676	2e-16	92.0
rs:WP_005172815	DNA topoisomerase I [Acinetobacter sp. NIPH 713].	27.30	348	206	12	48	384	276	587	2e-16	92.4
rs:WP_019641165	DNA topoisomerase I [Thioalkalivibrio sp. ALSr1].	27.84	334	195	8	61	377	248	552	2e-16	92.4
tr:A0A091U3E4_PHORB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.43	438	259	15	25	434	224	617	2e-16	92.4
rs:WP_014356315	DNA topoisomerase I [Acetobacterium woodii].	25.73	412	236	14	65	454	244	607	2e-16	92.0
rs:WP_017210743	DNA topoisomerase I [Clostridium beijerinckii].	23.72	409	250	12	66	454	242	608	2e-16	92.0
rs:WP_033946933	DNA topoisomerase I [Pseudomonas aeruginosa].	26.10	410	240	13	74	459	260	630	2e-16	92.0
rs:WP_005890473	DNA topoisomerase I subunit omega, partial [Pseudomonas coronafaciens].	26.60	391	234	15	69	446	9	359	2e-16	92.0
rs:WP_022744691	DNA topoisomerase 1 [Clostridium saccharobutylicum].	22.95	427	268	11	47	454	224	608	2e-16	92.0
rs:WP_022458468	DNA topoisomerase [Fusobacterium sp. CAG:439].	23.08	481	296	13	1	450	193	630	2e-16	92.0
rs:WP_019316381	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	2e-16	92.0
rs:WP_046464367	DNA topoisomerase I [Staphylococcus warneri].	23.29	425	265	15	47	452	224	606	2e-16	92.0
rs:WP_014281069	DNA topoisomerase I [Paenibacillus terrae].	25.18	413	249	14	65	457	242	614	2e-16	92.0
rs:XP_009886431	PREDICTED: DNA topoisomerase 3-beta-1 [Charadrius vociferus].	24.43	438	259	15	25	434	247	640	2e-16	92.4
rs:WP_046157929	DNA topoisomerase I [Chromobacterium vaccinii].	26.40	428	245	13	49	452	233	614	2e-16	92.0
tr:V9KDD5_CALMI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.25	466	289	16	18	455	254	683	2e-16	92.0
rs:WP_003126977	MULTISPECIES: DNA topoisomerase I [Enterococcus].	23.30	442	283	14	34	457	211	614	2e-16	92.0
rs:WP_028521365	DNA topoisomerase I [Ruminococcus flavefaciens].	24.24	429	267	11	43	452	221	610	2e-16	92.0
tr:R2B473_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOF89207.1};	31.58	190	113	6	274	454	8	189	2e-16	88.6
rs:WP_016186990	DNA topoisomerase III, partial [Staphylococcus aureus].	29.70	202	132	5	251	450	13	206	2e-16	89.4
rs:WP_012152659	DNA topoisomerase I [Rickettsia massiliae].	24.72	445	257	18	41	449	225	627	2e-16	92.0
rs:WP_014634563	DNA topoisomerase I [Streptococcus salivarius].	24.04	441	263	15	34	452	238	628	2e-16	92.0
rs:WP_031630901	DNA topoisomerase 1 [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	2e-16	92.0
rs:WP_015158856	DNA topoisomerase I [Chamaesiphon minutus].	25.17	441	260	16	23	439	216	610	2e-16	92.0
rs:WP_002989768	MULTISPECIES: DNA topoisomerase I [Streptococcus].	22.99	422	259	14	50	452	250	624	2e-16	92.0
rs:WP_002285804	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	2e-16	92.0
rs:WP_002476657	DNA topoisomerase I [Staphylococcus epidermidis].	23.93	422	260	14	50	452	227	606	2e-16	92.0
rs:XP_001988332	GH11108 [Drosophila grimshawi].	24.23	454	260	14	37	451	253	661	2e-16	92.4
rs:WP_041119071	DNA topoisomerase I [Enterococcus gallinarum].	23.30	442	283	14	34	457	211	614	2e-16	92.0
rs:WP_047951714	DNA topoisomerase I [Neisseria gonorrhoeae].	24.22	483	261	14	43	454	228	676	2e-16	92.0
rs:WP_009757221	DNA topoisomerase I [Lachnospiraceae bacterium 2_1_46FAA].	24.41	426	268	15	48	457	227	614	2e-16	92.0
rs:WP_022423481	DNA topoisomerase [Clostridium sp. CAG:440].	32.50	160	100	5	245	398	42	199	2e-16	87.8
rs:XP_007174215	PREDICTED: DNA topoisomerase 3-alpha [Balaenoptera acutorostrata scammoni].	26.00	427	242	15	60	455	310	693	2e-16	92.4
rs:XP_010396475	PREDICTED: DNA topoisomerase 3-beta-1 [Corvus cornix cornix].	24.64	422	247	14	40	434	238	615	2e-16	92.0
tr:F8XQU4_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	31.01	316	185	9	32	342	209	496	2e-16	91.7
tr:M0WQP1_HORVD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.23	446	256	17	39	452	266	670	2e-16	92.0
tr:W5E075_WHEAT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.28	449	252	18	39	452	266	670	2e-16	92.4
rs:WP_021422224	DNA topoisomerase I [Peptoclostridium difficile].	21.79	436	282	10	36	454	215	608	2e-16	92.0
rs:WP_040109967	hypothetical protein [Clostridium botulinum].	25.13	390	238	14	77	450	282	633	2e-16	92.0
rs:WP_002446285	DNA topoisomerase I [Staphylococcus epidermidis].	23.93	422	260	14	50	452	227	606	2e-16	92.0
rs:WP_017646538	DNA topoisomerase I [Streptococcus agalactiae].	22.43	437	276	13	34	452	229	620	2e-16	92.0
rs:WP_024732755	MULTISPECIES: DNA topoisomerase I [Clostridiales].	24.21	413	259	12	61	457	240	614	2e-16	92.0
rs:WP_028542727	DNA topoisomerase I [Paenibacillus sp. UNCCL52].	25.18	413	249	15	65	457	242	614	2e-16	92.0
rs:XP_009279084	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Aptenodytes forsteri].	24.43	438	259	15	25	434	111	504	2e-16	92.0
rs:WP_036140441	DNA topoisomerase I, partial [Lysobacter daejeonensis].	28.76	379	210	16	69	417	261	609	2e-16	92.0
rs:XP_009329018	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Pygoscelis adeliae].	24.43	438	259	15	25	434	247	640	2e-16	92.0
tr:E6W3Q7_DESIS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.29	435	266	16	36	452	216	609	2e-16	92.0
rs:WP_002234458	DNA topoisomerase I [Neisseria meningitidis].	24.02	483	262	14	43	454	228	676	2e-16	92.0
rs:WP_033910715	DNA topoisomerase I [Neisseria gonorrhoeae].	24.22	483	261	14	43	454	228	676	2e-16	92.0
rs:WP_005095508	DNA topoisomerase I [Acinetobacter lwoffii].	27.30	348	206	12	48	384	276	587	2e-16	92.0
rs:WP_025700243	DNA topoisomerase I [Paenibacillus durus].	25.12	434	253	17	50	457	227	614	2e-16	92.0
rs:WP_045642951	DNA topoisomerase I [Peptococcaceae bacterium BRH_c8a].	23.02	443	279	13	36	457	231	632	2e-16	92.0
rs:WP_034102734	DNA topoisomerase I [Desulfotomaculum sp. BICA1-6].	23.02	443	279	13	36	457	214	615	2e-16	92.0
tr:C9X1P3_NEIM8	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.02	483	262	14	43	454	228	676	2e-16	92.0
rs:WP_002225938	DNA topoisomerase I [Neisseria meningitidis].	24.02	483	262	14	43	454	228	676	2e-16	92.0
tr:Q12LR8_SHEDO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.30	365	213	12	42	388	273	599	2e-16	92.0
rs:XP_001684460	putative DNA topoisomerase III [Leishmania major strain Friedlin].	23.68	418	259	13	39	434	252	631	2e-16	92.0
rs:WP_002240198	DNA topoisomerase I [Neisseria meningitidis].	24.02	483	262	14	43	454	228	676	2e-16	92.0
tr:G5IUV3_9ENTE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.30	442	283	14	34	457	219	622	2e-16	92.0
rs:WP_023988184	DNA topoisomerase I [Paenibacillus polymyxa].	25.18	413	249	15	65	457	242	614	2e-16	92.0
rs:XP_011830675	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Mandrillus leucophaeus].	25.42	417	245	13	60	450	215	591	2e-16	92.0
rs:XP_009581659	PREDICTED: DNA topoisomerase 3-beta-1 [Fulmarus glacialis].	24.43	438	259	15	25	434	247	640	2e-16	92.0
tr:M0WQP4_HORVD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.23	446	256	17	39	452	266	670	2e-16	92.0
rs:WP_048037923	DNA topoisomerase [Methanosarcina mazei].	24.61	451	262	17	34	453	238	641	2e-16	92.0
rs:WP_002249911	DNA topoisomerase I [Neisseria meningitidis].	23.65	482	265	12	43	454	228	676	2e-16	92.0
tr:E8KVD5_STRVE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.04	441	263	15	34	452	117	507	2e-16	91.7
rs:WP_041405792	DNA topoisomerase I [Shewanella denitrificans].	26.30	365	213	12	42	388	257	583	2e-16	92.0
rs:WP_002450562	DNA topoisomerase I [Staphylococcus warneri].	23.29	425	265	15	47	452	224	606	2e-16	92.0
rs:WP_002453083	MULTISPECIES: DNA topoisomerase I [Staphylococcus].	23.06	425	266	14	47	452	224	606	2e-16	92.0
rs:XP_011830673	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Mandrillus leucophaeus].	25.42	417	245	13	60	450	310	686	2e-16	92.0
rs:WP_039295145	MULTISPECIES: DNA topoisomerase I [Paenibacillus].	24.01	429	264	13	50	457	227	614	2e-16	92.0
rs:WP_026147909	DNA topoisomerase I [Robiginitomaculum antarcticum].	25.84	445	257	15	45	454	227	633	2e-16	92.0
rs:WP_003092737	DNA topoisomerase I [Streptococcus vestibularis].	24.00	450	270	15	25	452	225	624	2e-16	92.0
rs:WP_009423475	DNA topoisomerase I [Fusobacterium sp. oral taxon 370].	26.63	323	190	8	69	377	251	540	2e-16	92.0
rs:WP_021375035	DNA topoisomerase I [Peptoclostridium difficile].	21.79	436	282	10	36	454	215	608	2e-16	92.0
tr:U5UP87_9STAP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.53	425	264	15	47	452	181	563	2e-16	91.7
rs:XP_012433502	PREDICTED: DNA topoisomerase 3-beta-1 [Taeniopygia guttata].	24.43	438	259	15	25	434	316	709	2e-16	92.0
rs:XP_008301573	PREDICTED: DNA topoisomerase 3-alpha [Stegastes partitus].	24.35	464	281	17	24	456	286	710	2e-16	92.0
rs:WP_011032137	MULTISPECIES: DNA topoisomerase [Methanosarcina].	24.61	451	262	17	34	453	238	641	2e-16	92.0
rs:XP_009938839	PREDICTED: DNA topoisomerase 3-beta-1 [Opisthocomus hoazin].	24.43	438	259	15	25	434	247	640	2e-16	92.0
rs:WP_021939311	DNA topoisomerase [Coprococcus sp. CAG:782].	25.11	438	267	12	39	454	215	613	2e-16	92.0
rs:WP_002281097	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	2e-16	92.0
rs:WP_040445183	DNA topoisomerase I [[Eubacterium] yurii].	23.52	438	261	12	43	457	220	606	2e-16	92.0
rs:XP_002970788	hypothetical protein SELMODRAFT_94303 [Selaginella moellendorffii].	23.71	464	275	16	28	452	248	671	2e-16	92.0
rs:WP_012608703	DNA topoisomerase I [Desulfurococcus kamchatkensis].	25.32	391	243	14	47	424	259	613	2e-16	92.0
rs:WP_010981052	DNA topoisomerase I [Neisseria meningitidis].	23.65	482	265	12	43	454	228	676	2e-16	92.0
rs:WP_028716244	DNA topoisomerase I [Paracoccus sp. J39].	25.87	429	257	14	51	454	233	625	2e-16	92.0
rs:WP_011971973	DNA topoisomerase I [Methanococcus vannielii].	23.76	463	276	17	18	454	216	627	2e-16	92.0
rs:WP_011304445	DNA topoisomerase I [Ehrlichia canis].	25.57	438	256	13	47	452	232	631	2e-16	92.0
rs:WP_022338804	DNA topoisomerase [Clostridium sp. CAG:433].	24.42	385	239	10	77	443	282	632	2e-16	92.0
rs:WP_030132832	DNA topoisomerase I [Mycobacterium neoaurum].	26.79	392	233	13	41	410	268	627	2e-16	92.0
rs:WP_009021608	topoisomerase I [Luminiphilus syltensis].	27.93	401	234	16	67	452	283	643	2e-16	92.0
rs:XP_004386256	PREDICTED: DNA topoisomerase 3-beta-1 [Trichechus manatus latirostris].	23.81	441	256	16	40	453	263	650	2e-16	92.0
rs:WP_024650439	hypothetical protein [Pseudomonas syringae].	27.85	377	207	17	90	446	260	591	2e-16	91.7
rs:WP_015365079	MULTISPECIES: DNA topoisomerase I [Staphylococcus].	23.29	425	265	15	47	452	224	606	2e-16	91.7
rs:WP_022407582	DNA topoisomerase [Bacillus sp. CAG:988].	26.72	408	238	15	60	450	234	597	2e-16	91.7
rs:WP_048009036	DNA topoisomerase I [Bacillus firmus].	24.49	437	251	18	50	457	227	613	2e-16	91.7
rs:WP_020445669	DNA topoisomerase I [Salinarchaeum sp. Harcht-Bsk1].	24.94	397	231	16	86	454	298	655	2e-16	92.0
rs:WP_000246601	DNA topoisomerase I [Streptococcus agalactiae].	22.43	437	276	13	34	452	229	620	2e-16	91.7
rs:WP_040848521	DNA topoisomerase I, partial [Thiothrix flexilis].	27.37	380	216	14	50	404	238	582	2e-16	92.0
rs:WP_013309879	DNA topoisomerase I [Paenibacillus polymyxa].	25.18	413	249	15	65	457	242	614	2e-16	91.7
rs:WP_008204102	DNA topoisomerase I [Roseobacter sp. SK209-2-6].	26.19	462	254	18	41	454	225	647	2e-16	92.0
rs:WP_002286698	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	2e-16	91.7
rs:WP_002283154	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	2e-16	91.7
rs:XP_005421521	PREDICTED: DNA topoisomerase 3-beta-1 [Geospiza fortis].	24.43	438	259	15	25	434	222	615	2e-16	92.0
rs:WP_036463333	DNA topoisomerase I [Mycobacterium sp. UNCCL9].	26.79	392	233	13	41	410	268	627	2e-16	92.0
rs:WP_014533317	DNA topoisomerase I [Staphylococcus lugdunensis].	24.00	425	258	14	47	452	224	602	2e-16	91.7
tr:A0A061NPP8_9BACL	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAK04500.1};	32.11	218	129	8	242	454	4	207	2e-16	88.6
rs:WP_011847016	topoisomerase I [Shewanella baltica].	26.18	424	259	15	35	446	250	631	2e-16	92.0
rs:WP_003045929	hypothetical protein [Streptococcus canis].	26.67	345	219	10	59	399	263	577	2e-16	91.7
rs:WP_019318811	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	2e-16	91.7
rs:WP_002272153	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	2e-16	91.7
rs:WP_002221835	DNA topoisomerase I [Neisseria meningitidis].	24.02	483	262	14	43	454	228	676	2e-16	92.0
rs:WP_038067626	DNA topoisomerase I [Thioclava dalianensis].	24.42	475	263	14	41	454	222	661	2e-16	92.0
rs:WP_008587919	DNA topoisomerase I [Salimicrobium jeotgali].	25.47	428	261	16	49	457	227	615	3e-16	91.7
rs:WP_011320483	DNA topoisomerase I [Anabaena variabilis].	24.25	433	249	15	40	445	241	621	3e-16	91.7
rs:WP_036069502	DNA topoisomerase I [Listeria rocourtiae].	23.19	427	269	14	50	457	227	613	3e-16	91.7
tr:V9KK95_CALMI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.03	466	290	16	18	455	233	662	3e-16	91.7
rs:WP_007953650	DNA topoisomerase I [Pelosinus fermentans].	25.78	419	247	15	60	457	239	614	3e-16	91.7
rs:WP_002238601	DNA topoisomerase I [Neisseria meningitidis].	24.02	483	262	14	43	454	228	676	3e-16	92.0
rs:WP_005239880	MULTISPECIES: topoisomerase I [Acinetobacter].	27.10	321	194	10	40	356	267	551	3e-16	92.0
rs:WP_008789958	MULTISPECIES: DNA topoisomerase I [Coprobacillus].	24.81	403	248	11	61	450	239	599	3e-16	91.7
rs:XP_394050	PREDICTED: DNA topoisomerase 3-alpha-like [Apis mellifera].	24.89	446	259	15	39	452	256	657	3e-16	92.0
rs:WP_003083749	DNA topoisomerase I [Streptococcus porcinus].	23.02	443	266	16	34	452	233	624	3e-16	91.7
rs:WP_043367683	MULTISPECIES: DNA topoisomerase I [Mycobacterium].	26.79	392	233	13	41	410	267	626	3e-16	92.0
rs:WP_005278819	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	27.10	321	194	10	40	356	267	551	3e-16	92.0
tr:G0V1K6_TRYCI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.69	325	188	11	65	379	279	566	3e-16	92.0
rs:XP_010202476	PREDICTED: DNA topoisomerase 3-beta-1 [Colius striatus].	24.49	437	258	15	26	434	248	640	3e-16	92.0
rs:XP_009279077	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Aptenodytes forsteri].	24.43	438	259	15	25	434	247	640	3e-16	92.0
rs:WP_045734776	DNA topoisomerase I, partial [Pseudomonas pseudoalcaligenes].	25.94	397	241	13	47	431	258	613	3e-16	91.7
rs:WP_021380353	DNA topoisomerase I [Peptoclostridium difficile].	21.79	436	282	10	36	454	215	608	3e-16	91.7
tr:G3NY56_GASAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.16	461	279	17	24	455	239	662	3e-16	91.7
tr:G7NJ30_MACMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.42	417	245	13	60	450	310	686	3e-16	92.0
rs:WP_007047795	DNA topoisomerase I [Subdoligranulum variabile].	26.09	460	249	18	47	449	226	651	3e-16	91.7
rs:XP_010186423	PREDICTED: DNA topoisomerase 3-beta-1 [Mesitornis unicolor].	24.41	422	248	14	40	434	263	640	3e-16	92.0
rs:WP_043023131	DNA topoisomerase I [Lactobacillus brevis].	25.28	439	259	15	41	457	234	625	3e-16	91.7
rs:WP_000179640	DNA topoisomerase I [Streptococcus pneumoniae].	24.51	408	237	13	66	452	254	611	3e-16	91.7
rs:WP_036621536	DNA topoisomerase I [Paenibacillus alvei].	23.02	443	282	14	35	457	211	614	3e-16	91.7
rs:WP_019314697	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	3e-16	91.7
tr:G3SN49_LOXAF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.94	445	265	16	40	455	291	695	3e-16	92.0
tr:A0A063ZJV9_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.08	436	280	16	31	454	254	650	3e-16	92.0
rs:WP_035517327	DNA topoisomerase I [Pseudohaliea rubra].	25.30	423	263	13	44	452	262	645	3e-16	92.0
rs:XP_010598538	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Loxodonta africana].	24.94	445	265	16	40	455	206	610	3e-16	92.0
rs:WP_042738862	DNA topoisomerase I [Staphylococcus gallinarum].	25.32	395	233	16	77	452	254	605	3e-16	91.7
rs:WP_002282013	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	3e-16	91.7
tr:R5Q3X4_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.53	392	223	12	77	450	255	599	3e-16	91.7
rs:XP_009976028	PREDICTED: DNA topoisomerase 3-beta-1 [Tauraco erythrolophus].	24.66	438	258	15	25	434	247	640	3e-16	92.0
rs:WP_002502089	DNA topoisomerase I [Staphylococcus epidermidis].	23.93	422	260	14	50	452	227	606	3e-16	91.7
rs:WP_040410425	DNA topoisomerase I [[Clostridium] hiranonis].	22.35	425	271	9	47	454	226	608	3e-16	91.7
rs:WP_002218552	DNA topoisomerase I [Neisseria meningitidis].	24.02	483	262	14	43	454	228	676	3e-16	91.7
rs:WP_018372628	DNA topoisomerase I [Streptococcus merionis].	23.75	459	281	15	18	452	200	613	3e-16	91.7
rs:WP_035526289	DNA topoisomerase I [Hoeflea sp. BAL378].	26.49	419	248	13	67	452	248	639	3e-16	92.0
tr:B6FZ87_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.35	425	271	9	47	454	232	614	3e-16	91.7
rs:WP_009536215	DNA topoisomerase I [Oribacterium asaccharolyticum].	25.35	426	255	15	49	454	228	610	3e-16	91.7
rs:WP_044644877	DNA topoisomerase I [Paenibacillus terrae].	25.18	413	249	14	65	457	242	614	3e-16	91.7
rs:WP_002250953	DNA topoisomerase I [Neisseria meningitidis].	24.02	483	262	14	43	454	228	676	3e-16	91.7
rs:WP_005083647	DNA topoisomerase I [Acinetobacter haemolyticus].	27.10	321	194	10	40	356	267	551	3e-16	92.0
rs:WP_019802704	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	3e-16	91.7
rs:WP_027623453	DNA topoisomerase I [Clostridium lundense].	23.12	519	287	19	1	449	170	646	3e-16	91.7
rs:WP_034024827	DNA topoisomerase 1 [Pseudomonas aeruginosa].	25.74	408	256	13	47	446	257	625	3e-16	91.7
rs:WP_046338444	DNA topoisomerase I [Pasteurella multocida].	25.40	378	235	13	77	446	290	628	3e-16	91.7
rs:WP_037586178	DNA topoisomerase I [Stenoxybacter acetivorans].	25.88	425	249	15	51	452	235	616	3e-16	91.7
tr:A0A0D6DXL3_9LACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.11	448	255	17	34	452	282	673	3e-16	91.7
rs:WP_018017365	DNA topoisomerase I [Corynebacterium capitovis].	26.85	324	186	10	41	351	253	538	3e-16	92.0
rs:XP_002111020	hypothetical protein TRIADDRAFT_22834 [Trichoplax adhaerens].	25.66	343	213	8	59	393	278	586	3e-16	91.7
rs:WP_035886894	DNA topoisomerase I [Legionella norrlandica].	27.50	440	247	21	46	459	234	627	3e-16	91.7
rs:WP_037245763	DNA topoisomerase I [Roseovarius sp. MCTG156(2b)].	25.26	483	265	18	34	454	205	653	3e-16	91.7
rs:WP_017601719	DNA topoisomerase I [Nocardiopsis lucentensis].	27.09	358	213	12	36	377	265	590	3e-16	92.0
rs:WP_019226964	MULTISPECIES: DNA topoisomerase I [Clostridiales].	24.46	413	253	12	61	454	239	611	3e-16	91.7
rs:WP_002275904	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	3e-16	91.7
rs:WP_027327234	DNA topoisomerase I [Helicobacter pametensis].	25.87	402	242	12	67	454	244	603	3e-16	91.7
tr:G9X0K0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.70	224	130	8	66	286	253	456	3e-16	90.9
rs:WP_023665871	DNA topoisomerase I [Rhodobacter sp. CACIA14H1].	26.22	431	260	15	47	454	229	624	3e-16	91.7
rs:WP_040012714	DNA topoisomerase, partial [Peptostreptococcaceae bacterium ACC19a].	31.70	224	130	8	66	286	253	456	3e-16	90.9
tr:A0A087Y9R3_POEFO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.25	433	244	12	60	455	285	670	3e-16	92.0
tr:A0A087QIU6_APTFO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.43	438	259	15	25	434	224	617	3e-16	91.7
rs:WP_015140585	DNA topoisomerase I [Nostoc sp. PCC 7524].	26.51	347	214	9	41	377	249	564	3e-16	91.7
rs:WP_023916854	DNA topoisomerase III [Streptococcus sanguinis].	26.86	350	214	12	61	402	265	580	3e-16	91.3
tr:H0ZEB7_TAEGU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.43	438	259	15	25	434	224	617	3e-16	91.7
rs:WP_017638385	DNA topoisomerase I [Staphylococcus sp. E463].	23.06	425	266	14	47	452	224	606	3e-16	91.7
rs:WP_006672595	DNA topoisomerase I [Halobiforma nitratireducens].	24.32	407	256	13	60	454	267	633	3e-16	91.7
tr:M3ZNA2_XIPMA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.19	434	243	13	60	455	325	710	3e-16	92.0
rs:WP_048298257	DNA topoisomerase I [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	275	626	3e-16	91.7
rs:WP_018449835	DNA topoisomerase I [Leptotrichia shahii].	25.13	386	226	12	18	379	186	532	3e-16	91.7
rs:XP_010579935	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Haliaeetus leucocephalus].	24.43	438	259	15	25	434	150	543	3e-16	91.7
rs:WP_016860420	DNA topoisomerase I [Fischerella muscicola].	25.84	356	225	8	41	387	255	580	3e-16	91.7
rs:WP_039643387	DNA topoisomerase I [Geobacter soli].	25.31	482	257	18	43	457	228	673	3e-16	91.7
rs:WP_006736530	DNA topoisomerase I [Lactobacillus iners].	22.71	480	299	17	1	452	175	610	3e-16	91.7
rs:WP_005044934	DNA topoisomerase I [Acinetobacter calcoaceticus].	26.93	427	255	19	40	452	266	649	3e-16	91.7
rs:XP_010579932	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Haliaeetus leucocephalus].	24.43	438	259	15	25	434	222	615	3e-16	91.7
tr:A0A093C6P9_TAUER	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.66	438	258	15	25	434	224	617	3e-16	91.7
rs:WP_034436080	DNA topoisomerase I [Clostridiales bacterium S5-A11].	24.37	435	271	14	36	454	246	638	3e-16	91.7
rs:WP_013731070	DNA topoisomerase I [Verrucosispora maris].	26.85	365	213	14	42	386	261	591	3e-16	91.7
tr:G6BMM8_PEPDI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.90	443	273	10	36	454	221	614	3e-16	91.7
rs:WP_008942315	MULTISPECIES: topoisomerase I [Acinetobacter].	27.10	321	194	10	40	356	267	551	3e-16	91.7
rs:WP_012720245	hypothetical protein [Clostridium botulinum].	25.19	385	235	13	77	446	282	628	3e-16	91.7
tr:A0A091RFY7_9GRUI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.41	422	248	14	40	434	240	617	3e-16	91.7
rs:WP_047758868	DNA topoisomerase I [Wolbachia endosymbiont of Armadillidium vulgare].	24.89	442	254	15	47	452	231	630	3e-16	91.7
rs:WP_016421939	MULTISPECIES: DNA topoisomerase I [Corynebacterium].	25.68	366	228	10	37	386	257	594	3e-16	91.7
rs:WP_038810540	DNA topoisomerase I [Peptoclostridium difficile].	21.90	443	273	10	36	454	215	608	3e-16	91.7
rs:XP_010579931	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Haliaeetus leucocephalus].	24.43	438	259	15	25	434	247	640	3e-16	91.7
rs:XP_008140862	PREDICTED: DNA topoisomerase 3-beta-1 [Eptesicus fuscus].	23.58	441	257	16	40	453	263	650	3e-16	91.7
rs:WP_034996971	DNA topoisomerase I [Corynebacterium sp. GD7].	26.87	335	199	10	30	354	245	543	3e-16	91.7
tr:A0A0A7U047_LACBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.28	439	259	15	41	457	235	626	3e-16	91.7
rs:WP_046599101	DNA topoisomerase I [Pseudomonas aeruginosa].	25.61	410	242	13	74	459	260	630	3e-16	91.3
rs:WP_022240234	DNA topoisomerase [Clostridium sp. CAG:413].	23.85	478	253	15	40	449	217	651	3e-16	91.7
tr:G1FGU3_9CHLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.82	427	262	14	47	454	243	629	3e-16	91.7
tr:S9SHB1_PAEAL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.02	443	282	14	35	457	223	626	3e-16	91.7
rs:XP_003762778	PREDICTED: DNA topoisomerase 3-beta-1 [Sarcophilus harrisii].	23.13	467	275	18	18	453	176	589	3e-16	91.7
rs:WP_007144187	DNA topoisomerase I [Methylophaga aminisulfidivorans].	27.15	431	247	18	46	452	234	621	3e-16	91.7
tr:F3GJ48_PSESJ	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGH47101.1}; Flags: Fragment;	32.69	208	121	6	51	249	93	290	3e-16	88.6
rs:WP_022579620	DNA topoisomerase I [Pseudomonas aeruginosa].	25.61	410	242	13	74	459	260	630	3e-16	91.3
rs:WP_005379878	DNA topoisomerase I [Veillonella atypica].	24.58	476	299	16	1	454	233	670	3e-16	91.7
rs:WP_040561971	DNA topoisomerase I [Prevotella buccalis].	28.08	260	156	7	77	334	252	482	3e-16	91.7
rs:XP_004042226	PREDICTED: DNA topoisomerase 3-alpha [Gorilla gorilla gorilla].	25.75	400	231	13	77	450	302	661	3e-16	91.7
rs:WP_021387786	DNA topoisomerase I [Peptoclostridium difficile].	21.90	443	273	10	36	454	215	608	3e-16	91.7
rs:WP_037563180	hypothetical protein [Spirochaeta sp. JC202].	26.14	440	246	18	36	450	230	615	3e-16	91.7
rs:WP_002242228	DNA topoisomerase I [Neisseria meningitidis].	24.02	483	262	14	43	454	228	676	3e-16	91.7
rs:WP_002220143	DNA topoisomerase I [Neisseria meningitidis].	24.02	483	262	14	43	454	228	676	3e-16	91.7
rs:XP_003420711	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Loxodonta africana].	24.94	445	265	16	40	455	289	693	3e-16	91.7
rs:WP_000341351	DNA topoisomerase I, partial [Streptococcus agalactiae].	22.43	437	276	13	34	452	125	516	3e-16	91.3
rs:WP_004637808	topoisomerase I [Acinetobacter haemolyticus].	26.40	356	215	11	40	384	267	586	3e-16	91.7
rs:WP_018935946	DNA topoisomerase I [Thioalkalivibrio sp. ALJ24].	28.29	304	175	7	61	350	248	522	3e-16	91.7
tr:A0A093G994_PICPB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.97	438	261	15	25	434	224	617	3e-16	91.7
rs:WP_002273112	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	3e-16	91.7
rs:WP_002498363	DNA topoisomerase I [Staphylococcus epidermidis].	23.52	421	263	13	50	452	227	606	3e-16	91.7
rs:WP_017668615	hypothetical protein [Sandarakinorhabdus sp. AAP62].	27.27	418	247	17	60	454	242	625	3e-16	91.7
rs:WP_033975944	DNA topoisomerase 1 [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	3e-16	91.7
rs:WP_034052320	DNA topoisomerase I [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	3e-16	91.7
rs:WP_034033495	DNA topoisomerase I [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	3e-16	91.7
rs:WP_013128447	DNA topoisomerase I [Tsukamurella paurometabola].	27.11	343	196	11	35	354	250	561	3e-16	91.7
rs:WP_035641699	DNA topoisomerase I [Lachnospiraceae bacterium FE2018].	24.55	440	275	11	34	454	212	613	3e-16	91.7
rs:WP_022956231	topoisomerase I [Perlucidibaca piscinae].	25.93	428	257	15	47	458	264	647	3e-16	91.7
tr:A9M455_NEIM0	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.65	482	265	12	43	454	208	656	3e-16	91.7
rs:WP_014925151	DNA topoisomerase I [Gordonia sp. KTR9].	26.26	396	238	13	37	409	262	626	3e-16	91.7
rs:XP_002199057	PREDICTED: DNA topoisomerase 3-beta-1 [Taeniopygia guttata].	24.43	438	259	15	25	434	387	780	3e-16	91.7
gp:CP010942_735	DNA topoisomerase I [Staphylococcus epidermidis]	23.93	422	260	14	50	452	227	606	3e-16	91.7
rs:WP_038123375	DNA topoisomerase I [Veillonella sp. ICM51a].	24.16	476	301	15	1	454	233	670	3e-16	91.7
rs:WP_009117526	DNA topoisomerase I [Neisseria wadsworthii].	25.12	434	261	13	41	452	225	616	3e-16	91.7
rs:XP_010118399	PREDICTED: DNA topoisomerase 3-beta-1 [Chlamydotis macqueenii].	24.29	457	265	17	25	453	247	650	3e-16	91.7
rs:WP_018981455	topoisomerase I [Salinimonas chungwhensis].	26.32	418	252	17	42	446	256	630	3e-16	91.7
rs:WP_005001350	DNA topoisomerase I [Acinetobacter ursingii].	26.29	426	259	18	40	452	269	652	3e-16	91.7
rs:WP_025684918	DNA topoisomerase I [Paenibacillus sp. 1-49].	25.18	413	249	14	65	457	242	614	3e-16	91.7
tr:A0A0C1NEQ2_9CYAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.48	313	186	9	77	379	289	570	3e-16	91.7
rs:WP_033996124	DNA topoisomerase I [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	3e-16	91.7
rs:WP_048295950	DNA topoisomerase I [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	3e-16	91.7
rs:WP_035078850	DNA topoisomerase I [Devosia riboflavina].	27.23	415	250	17	60	452	243	627	3e-16	91.7
rs:WP_007934880	MULTISPECIES: DNA topoisomerase I [Pelosinus].	25.54	419	248	15	60	457	239	614	3e-16	91.7
gpu:CP003421_270	DNA topoisomerase I [Corynebacterium pseudotuberculosis 31]	25.88	371	228	11	31	384	254	594	3e-16	91.7
tr:J9FNX8_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EJW96163.1}; Flags: Fragment;	31.23	253	134	10	209	452	9	230	3e-16	87.8
rs:WP_031640548	DNA topoisomerase I [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	3e-16	91.7
rs:WP_033950115	DNA topoisomerase I [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	262	613	3e-16	91.7
rs:XP_007910121	PREDICTED: DNA topoisomerase 3-alpha [Callorhinchus milii].	25.24	420	254	14	60	455	300	683	3e-16	91.7
rs:WP_035991054	DNA topoisomerase I [Leptolyngbya sp. KIOST-1].	27.54	403	233	13	24	398	228	599	3e-16	91.7
tr:G3W4B1_SARHA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.13	467	275	18	18	453	140	553	3e-16	91.7
rs:WP_045792501	DNA topoisomerase I [Acinetobacter brisouii].	26.46	427	257	18	40	452	268	651	3e-16	91.7
rs:WP_024785984	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	3e-16	91.3
rs:WP_037555477	DNA topoisomerase I [Staphylococcus sp. URHA0057].	23.06	425	266	14	47	452	224	606	3e-16	91.3
rs:WP_012075146	topoisomerase I [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	3e-16	91.7
rs:WP_047821083	DNA topoisomerase I [Croceicoccus naphthovorans].	25.93	486	293	16	1	452	171	623	3e-16	91.7
rs:WP_010491323	DNA topoisomerase I [Paenibacillus elgii].	25.06	447	271	15	35	457	211	617	3e-16	91.3
rs:WP_019503055	hypothetical protein [Pseudanabaena sp. PCC 6802].	28.12	352	206	11	41	379	249	566	3e-16	91.7
rs:WP_004996071	DNA topoisomerase I [Rickettsia sibirica].	25.54	415	242	16	65	449	250	627	3e-16	91.7
rs:WP_043029703	DNA topoisomerase I [Streptococcus equi].	23.53	459	274	14	19	452	219	625	3e-16	91.3
rs:WP_028575888	DNA topoisomerase I [Desulfonatronovibrio hydrogenovorans].	25.77	423	254	13	47	452	225	604	3e-16	91.7
tr:A0A0A8RCV9_PSEAI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.32	391	241	12	68	446	274	625	3e-16	91.7
rs:WP_007524326	topoisomerase I [Haemophilus sputorum].	25.00	468	278	18	3	452	227	639	3e-16	91.7
rs:WP_025899806	DNA topoisomerase I [Sneathiella glossodoripedis].	26.89	424	234	16	65	452	249	632	3e-16	91.7
rs:WP_002642410	DNA topoisomerase I [Simonsiella muelleri].	25.29	431	265	12	41	452	227	619	3e-16	91.7
rs:WP_036968862	DNA topoisomerase I [Pseudoalteromonas lipolytica].	26.65	394	234	16	66	446	280	631	3e-16	91.7
rs:WP_047916589	DNA topoisomerase I [Lactococcus piscium].	24.11	448	255	17	34	452	235	626	3e-16	91.3
rs:WP_021983662	GTP-sensing transcriptional pleiotropic repressor CodY [Eubacterium sp. CAG:603].	23.94	426	265	13	48	454	227	612	3e-16	91.3
rs:WP_021384059	DNA topoisomerase I [Peptoclostridium difficile].	21.79	436	282	10	36	454	215	608	3e-16	91.3
rs:WP_002483473	DNA topoisomerase 1 [Staphylococcus saprophyticus].	22.69	432	272	13	40	452	217	605	3e-16	91.3
rs:WP_045108467	DNA topoisomerase I [Pseudomonas sp. HMSC05H02].	25.32	391	241	12	68	446	274	625	3e-16	91.7
rs:WP_000246600	DNA topoisomerase I [Streptococcus agalactiae].	22.43	437	276	13	34	452	229	620	3e-16	91.3
rs:WP_038627467	DNA topoisomerase I [Corynebacterium sp. ATCC 6931].	25.14	362	228	9	40	386	261	594	3e-16	91.7
rs:WP_005689318	DNA topoisomerase I [Lactobacillus rhamnosus].	24.19	434	259	13	43	452	223	610	3e-16	91.3
rs:WP_002224383	DNA topoisomerase I [Neisseria meningitidis].	24.02	483	262	14	43	454	228	676	3e-16	91.7
tr:D1W2V0_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.08	260	156	7	77	334	266	496	3e-16	91.7
rs:WP_031806109	DNA topoisomerase I [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	3e-16	91.7
tr:X1M4R7_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_C00692 {ECO:0000313|EMBL:GAI01364.1};	25.28	360	208	11	112	453	6	322	3e-16	89.7
rs:XP_010328854	PREDICTED: DNA topoisomerase 3-beta-1 [Saimiri boliviensis boliviensis].	24.34	456	265	17	25	453	219	621	3e-16	91.7
tr:A0A0E9P4C7_9SPHN	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAO56560.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAO56560.1};	27.07	458	262	17	31	452	199	620	3e-16	91.7
rs:WP_015473756	DNA topoisomerase 1 [Lactobacillus brevis].	25.28	439	259	15	41	457	234	625	3e-16	91.3
rs:WP_034069888	DNA topoisomerase 1 [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	3e-16	91.7
rs:WP_034613184	DNA topoisomerase I [Chelonobacter oris].	25.11	446	278	16	18	446	222	628	3e-16	91.7
rs:WP_039261035	DNA topoisomerase I [Clostridium tetani].	24.43	397	239	12	77	454	254	608	3e-16	91.3
rs:XP_010301850	PREDICTED: DNA topoisomerase 3-beta-1 [Balearica regulorum gibbericeps].	24.43	438	259	15	25	434	247	640	3e-16	91.7
rs:WP_039457938	DNA topoisomerase I [Thermus sp. 2.9].	26.81	414	227	15	61	454	264	621	3e-16	91.7
rs:WP_046738240	DNA topoisomerase I [Acinetobacter sp. AG1].	27.10	321	194	10	40	356	267	551	3e-16	91.7
rs:WP_024947862	DNA topoisomerase I [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	272	623	3e-16	91.7
rs:WP_034025524	DNA topoisomerase I [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	3e-16	91.7
rs:WP_048293289	DNA topoisomerase I [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	276	627	3e-16	91.7
rs:WP_011322338	DNA topoisomerase I [Natronomonas pharaonis].	23.53	374	248	8	86	454	290	630	3e-16	91.7
rs:XP_009090585	PREDICTED: DNA topoisomerase 3-beta-1 [Serinus canaria].	24.43	438	259	15	25	434	247	640	3e-16	91.7
rs:WP_034005999	DNA topoisomerase I [Pseudomonas aeruginosa].	25.61	410	242	13	74	459	260	630	3e-16	91.3
rs:WP_023429490	DNA topoisomerase I, archaeal [uncultured Acidilobus sp. JCHS].	28.54	396	231	13	45	425	242	600	3e-16	91.3
rs:WP_048297048	DNA topoisomerase I [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	276	627	3e-16	91.7
rs:WP_032802204	DNA topoisomerase I [Corynebacterium pseudotuberculosis].	25.88	371	228	11	31	384	249	589	3e-16	91.7
rs:WP_021085359	DNA topoisomerase I [Campylobacter concisus].	27.16	394	219	17	77	450	254	599	4e-16	91.3
tr:G3NY50_GASAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.16	461	279	17	24	455	243	666	4e-16	91.7
rs:WP_023114523	DNA topoisomerase 1 [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	4e-16	91.7
rs:XP_007574411	PREDICTED: DNA topoisomerase 3-alpha [Poecilia formosa].	24.25	433	244	12	60	455	325	710	4e-16	91.7
rs:WP_021974742	DNA topoisomerase [Firmicutes bacterium CAG:884].	24.55	387	241	13	77	449	277	626	4e-16	91.3
rs:WP_014366395	DNA topoisomerase I [Corynebacterium pseudotuberculosis].	25.88	371	228	11	31	384	249	589	4e-16	91.7
rs:WP_002282653	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	4e-16	91.3
sp:TOP1_PSEAE	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.32	391	241	12	68	446	274	625	4e-16	91.7
rs:WP_033936377	DNA topoisomerase I [Pseudomonas aeruginosa].	25.61	410	242	13	74	459	260	630	4e-16	91.3
rs:WP_044195038	DNA topoisomerase I [Ehrlichia sp. HF].	25.86	437	256	13	47	452	232	631	4e-16	91.3
rs:WP_022433392	DNA topoisomerase [Eubacterium sp. CAG:38].	25.45	444	266	17	36	457	69	469	4e-16	90.9
rs:WP_027895073	DNA topoisomerase I [Megasphaera elsdenii].	24.84	471	274	17	18	452	240	666	4e-16	91.3
rs:WP_002262866	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	4e-16	91.3
rs:WP_033987437	DNA topoisomerase 1 [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	4e-16	91.7
rs:WP_034001363	DNA topoisomerase I [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	4e-16	91.7
rs:WP_022668783	DNA topoisomerase I [Desulfospira joergensenii].	25.23	432	258	15	43	452	226	614	4e-16	91.3
tr:L1PYG3_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.95	476	302	15	1	454	236	673	4e-16	91.3
rs:WP_000246603	DNA topoisomerase I [Streptococcus agalactiae].	22.43	437	276	13	34	452	229	620	4e-16	91.3
tr:W7CZJ8_9LIST	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EUJ42195.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EUJ42195.1};	26.51	298	176	11	166	452	21	286	4e-16	89.7
rs:WP_029140909	DNA topoisomerase I [Streptococcus agalactiae].	22.43	437	276	13	34	452	229	620	4e-16	91.3
tr:A0A0D9VPW6_9ORYZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.57	437	279	12	39	452	269	673	4e-16	91.3
rs:WP_000246610	DNA topoisomerase I [Streptococcus agalactiae].	22.43	437	276	13	34	452	229	620	4e-16	91.3
rs:WP_018146992	DNA topoisomerase I [Henriciella marina].	25.34	438	272	13	41	454	224	630	4e-16	91.3
rs:WP_022253962	DNA topoisomerase [Firmicutes bacterium CAG:466].	25.63	437	254	20	41	454	3	391	4e-16	90.9
rs:XP_009909292	PREDICTED: DNA topoisomerase 3-beta-1 [Picoides pubescens].	23.97	438	261	15	25	434	247	640	4e-16	91.3
rs:WP_015853669	DNA topoisomerase I [Desulfovibrio salexigens].	23.76	425	256	11	47	451	225	601	4e-16	91.3
rs:WP_002300224	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	4e-16	91.3
rs:WP_000246613	DNA topoisomerase I [Streptococcus agalactiae].	22.43	437	276	13	34	452	229	620	4e-16	91.3
rs:WP_044642672	DNA topoisomerase I [Thermoactinomycetaceae bacterium GD1].	25.40	496	271	21	18	449	187	647	4e-16	91.3
rs:WP_013657322	DNA topoisomerase I [Cellulosilyticum lentocellum].	24.82	423	263	12	47	454	225	607	4e-16	91.3
rs:WP_033892277	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	229	580	4e-16	91.3
rs:WP_048339670	DNA topoisomerase I [Neisseria gonorrhoeae].	24.02	483	262	14	43	454	228	676	4e-16	91.3
rs:WP_012167784	DNA topoisomerase I [Acaryochloris marina].	25.56	446	254	18	25	439	211	609	4e-16	91.3
rs:WP_028629481	DNA topoisomerase I [Pseudomonas resinovorans].	25.06	411	263	11	42	446	254	625	4e-16	91.3
rs:WP_025706262	DNA topoisomerase I [Paenibacillus graminis].	24.88	434	254	15	50	457	227	614	4e-16	91.3
rs:WP_004070358	DNA topoisomerase I [Clostridium sp. ASF502].	26.91	431	251	15	48	457	227	614	4e-16	91.3
rs:WP_006702673	DNA topoisomerase I [Granulicatella elegans].	24.21	413	252	13	58	452	237	606	4e-16	91.3
rs:WP_033970640	DNA topoisomerase I [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	4e-16	91.3
rs:WP_017249339	DNA topoisomerase I [Brevibacillus brevis].	24.31	432	260	14	49	457	226	613	4e-16	91.3
gpu:CP010867_998	DNA topoisomerase 1 [Streptococcus agalactiae]	22.43	437	276	13	34	452	232	623	4e-16	91.3
rs:WP_019682694	topoisomerase I, partial [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	4e-16	91.3
rs:WP_022168066	DNA topoisomerase [Clostridium sp. CAG:221].	25.86	437	237	17	66	449	242	644	4e-16	91.3
rs:WP_022503383	DNA topoisomerase [Mycoplasma sp. CAG:776].	24.36	427	233	13	77	450	250	639	4e-16	91.3
rs:WP_033952254	DNA topoisomerase 1 [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	4e-16	91.3
rs:WP_039395112	DNA topoisomerase I, partial [Novosphingobium sp. MBES04].	26.38	436	258	13	41	452	222	618	4e-16	91.3
rs:WP_028009192	DNA topoisomerase I [Solimonas flava].	27.88	391	215	14	24	377	201	561	4e-16	91.3
rs:WP_009606631	DNA topoisomerase I [Turicibacter sp. HGF1].	25.85	414	236	13	58	450	236	599	4e-16	91.3
rs:WP_005762130	topoisomerase I [Pasteurella dagmatis].	24.87	378	237	13	77	446	290	628	4e-16	91.3
rs:WP_001933799	DNA topoisomerase I [Streptococcus agalactiae].	22.43	437	276	13	34	452	229	620	4e-16	91.3
rs:WP_015589399	DNA topoisomerase [Wolbachia endosymbiont of Drosophila simulans].	25.34	442	252	15	47	452	231	630	4e-16	91.3
rs:WP_029335400	DNA topoisomerase I [Exiguobacterium aurantiacum].	23.95	430	270	11	45	454	222	614	4e-16	91.3
rs:WP_047796197	DNA topoisomerase I [Staphylococcus capitis].	23.06	425	266	14	47	452	224	606	4e-16	91.3
rs:WP_005662215	topoisomerase I [Haemophilus influenzae].	25.86	379	232	14	77	446	290	628	4e-16	91.3
rs:WP_000246614	DNA topoisomerase I [Streptococcus agalactiae].	22.65	437	275	14	34	452	229	620	4e-16	91.3
rs:WP_000246611	DNA topoisomerase I [Streptococcus agalactiae].	22.43	437	276	13	34	452	229	620	4e-16	91.3
rs:WP_009661275	DNA topoisomerase I [Veillonella sp. ACP1].	24.84	479	294	17	1	454	233	670	4e-16	91.3
rs:WP_040001828	DNA topoisomerase I [[Eubacterium] infirmum].	24.62	463	250	15	48	453	218	638	4e-16	91.3
rs:WP_037399481	DNA topoisomerase I [Sinorhizobium fredii].	25.34	438	266	13	47	452	230	638	4e-16	91.3
tr:A0A0E0NQ37_ORYRU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.77	440	264	15	39	452	270	668	4e-16	91.3
rs:WP_007232724	topoisomerase I [gamma proteobacterium HTCC2207].	24.88	434	256	17	40	452	264	648	4e-16	91.3
rs:WP_017414512	hypothetical protein [Clostridium tunisiense].	25.29	435	248	15	47	454	226	610	4e-16	91.3
rs:WP_026721293	DNA topoisomerase I [Fischerella sp. PCC 9431].	25.56	356	226	8	41	387	255	580	4e-16	91.3
rs:XP_012499600	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Propithecus coquereli].	23.63	457	268	17	25	453	247	650	4e-16	91.3
rs:WP_028327554	DNA topoisomerase I [Dermatophilus congolensis].	26.32	380	225	12	47	405	260	605	4e-16	91.3
rs:WP_023973319	DNA topoisomerase I [Clostridium pasteurianum].	24.33	411	245	14	66	454	242	608	4e-16	91.3
rs:WP_000246604	DNA topoisomerase I [Streptococcus agalactiae].	22.43	437	276	13	34	452	229	620	4e-16	91.3
rs:WP_015631990	DNA topoisomerase I [Streptococcus agalactiae].	22.43	437	276	13	34	452	229	620	4e-16	91.3
rs:WP_035148559	DNA topoisomerase I [Clostridium tetanomorphum].	27.10	417	226	17	66	454	244	610	4e-16	91.3
rs:WP_006086246	topoisomerase I [Shewanella baltica].	26.18	424	259	15	35	446	250	631	4e-16	91.3
rs:WP_039497466	DNA topoisomerase I [Pseudoalteromonas elyakovii].	25.42	417	257	15	42	446	257	631	4e-16	91.3
rs:WP_042775733	DNA topoisomerase I, partial [Sinorhizobium fredii].	25.23	440	264	14	47	452	13	421	4e-16	91.3
rs:WP_007599335	DNA topoisomerase I [Rhizobium sp. PDO1-076].	27.82	417	237	14	70	452	253	639	4e-16	91.3
rs:WP_029453258	DNA topoisomerase I [Clostridium algidicarnis].	23.73	434	260	15	43	452	220	606	4e-16	91.3
rs:WP_045574983	DNA topoisomerase I [Desulfosporosinus sp. I2].	25.64	429	257	16	48	454	225	613	4e-16	91.3
tr:A0A093FNA9_GAVST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.43	438	259	15	25	434	224	617	4e-16	91.3
rs:WP_006925268	DNA topoisomerase I [Bartonella washoensis].	27.76	425	232	19	67	452	248	636	4e-16	91.3
rs:WP_037468283	DNA topoisomerase I, partial [Sinorhizobium fredii].	25.23	440	264	14	47	452	12	420	4e-16	90.9
rs:WP_000246615	DNA topoisomerase I [Streptococcus agalactiae].	22.65	437	275	14	34	452	229	620	4e-16	91.3
rs:WP_036587972	DNA topoisomerase I [Paenibacillus sophorae].	25.12	434	253	17	50	457	227	614	4e-16	91.3
tr:F9N727_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.24	425	256	15	47	451	218	596	4e-16	91.3
rs:WP_002359812	DNA topoisomerase, partial [Enterococcus faecium].	29.87	231	150	5	57	284	268	489	4e-16	90.5
rs:XP_009816881	PREDICTED: DNA topoisomerase 3-beta-1 [Gavia stellata].	24.43	438	259	15	25	434	247	640	4e-16	91.3
tr:E6Q8V3_9ZZZZ	SubName: Full=DNA topoisomerase I, plasmid (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) {ECO:0000313|EMBL:CBI03629.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI03629.1};	27.49	422	243	15	43	444	216	594	4e-16	90.9
rs:WP_004993992	DNA topoisomerase I [Acinetobacter ursingii].	26.29	426	259	18	40	452	269	652	4e-16	91.3
rs:WP_038501935	DNA topoisomerase I [Rhodoluna lacicola].	28.33	353	198	13	25	356	235	553	4e-16	91.3
rs:WP_033974776	DNA topoisomerase I [Pseudomonas aeruginosa].	26.10	410	240	13	74	459	260	630	4e-16	90.9
rs:WP_010943185	DNA topoisomerase I [Geobacter sulfurreducens].	25.31	482	257	18	43	457	228	673	4e-16	91.3
rs:WP_004022112	DNA topoisomerase I [Gordonia terrae].	26.49	370	222	12	37	387	263	601	4e-16	91.3
rs:NP_224964	DNA topoisomerase I [Chlamydophila pneumoniae CWL029].	26.94	412	236	17	60	449	254	622	4e-16	91.3
tr:L7LY29_9ACAR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.95	371	212	12	40	394	257	584	4e-16	90.9
tr:G5GKI5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.09	215	123	8	75	286	279	473	4e-16	90.5
rs:WP_034872881	DNA topoisomerase I [Endozoicomonas montiporae].	26.55	388	233	15	77	452	296	643	4e-16	91.3
rs:WP_014062912	DNA topoisomerase I [Thermoanaerobacter wiegelii].	26.15	455	253	20	28	454	213	612	4e-16	90.9
rs:WP_003048468	DNA topoisomerase I [Streptococcus canis].	22.52	453	286	12	19	452	218	624	4e-16	91.3
rs:WP_004762171	DNA topoisomerase I [Acinetobacter sp. CIP 102129].	26.40	356	215	11	40	384	267	586	4e-16	91.3
rs:WP_020083156	topoisomerase I [gamma proteobacterium SCGC AAA160-D02].	24.70	417	261	12	47	452	271	645	4e-16	91.3
rs:WP_002305945	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	4e-16	91.3
rs:WP_017318697	DNA topoisomerase I [Mastigocladopsis repens].	25.39	382	230	10	41	398	252	602	4e-16	91.3
rs:WP_038148787	DNA topoisomerase I [Veillonella atypica].	23.95	476	302	15	1	454	233	670	4e-16	91.3
rs:WP_022090080	DNA topoisomerase [Clostridium sp. CAG:492].	22.65	437	280	12	36	454	215	611	4e-16	90.9
rs:WP_022463897	DNA topoisomerase [Clostridium sp. CAG:277].	24.59	427	259	13	48	454	230	613	4e-16	90.9
rs:WP_020583560	hypothetical protein [Endozoicomonas elysicola].	26.14	394	235	15	65	446	283	632	4e-16	91.3
rs:XP_003874672	putative DNA topoisomerase III [Leishmania mexicana MHOM/GT/2001/U1103].	27.02	359	211	11	37	379	244	567	4e-16	91.3
rs:WP_030507893	DNA topoisomerase I [Microbispora rosea].	27.09	358	212	13	37	374	250	578	4e-16	91.3
rs:XP_009971210	PREDICTED: DNA topoisomerase 3-beta-1 [Tyto alba].	24.34	456	264	17	26	453	248	650	4e-16	91.3
rs:WP_017939227	topoisomerase I [Pseudomonas thermotolerans].	25.00	408	259	13	47	446	255	623	4e-16	91.3
rs:WP_004991376	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	26.29	426	259	18	40	452	269	652	4e-16	91.3
rs:XP_004381055	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Trichechus manatus latirostris].	24.49	445	267	15	40	455	289	693	4e-16	91.3
rs:WP_022735463	DNA topoisomerase I [Candidatus Pelagibacter ubique].	26.62	417	234	18	73	454	255	634	4e-16	91.3
rs:WP_007014845	DNA topoisomerase I [Novosphingobium pentaromativorans].	26.67	435	258	14	41	452	222	618	4e-16	91.3
rs:WP_002245394	DNA topoisomerase I [Neisseria meningitidis].	24.02	483	262	14	43	454	228	676	4e-16	91.3
tr:A0A0D9VPW5_9ORYZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.57	437	279	12	39	452	269	673	4e-16	91.3
rs:WP_017644456	DNA topoisomerase I [Streptococcus agalactiae].	22.43	437	276	13	34	452	229	620	4e-16	90.9
tr:T1BLX4_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EQD73981.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EQD73981.1}; Flags: Fragment;	24.16	418	270	14	51	452	35	421	4e-16	90.9
rs:WP_010732770	DNA topoisomerase 1 [Enterococcus faecium].	24.33	448	271	14	34	457	211	614	4e-16	90.9
tr:A0A091PLN1_HALAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.33	433	264	14	25	434	147	534	4e-16	91.3
rs:WP_035132778	DNA topoisomerase I [Clostridium sulfidigenes].	23.58	458	258	13	47	449	226	646	4e-16	90.9
rs:WP_032121749	DNA topoisomerase I [Clostridium sp. LF2].	25.06	415	246	15	61	454	238	608	4e-16	90.9
rs:WP_006081959	topoisomerase I [Shewanella baltica].	26.18	424	259	15	35	446	250	631	4e-16	91.3
rs:XP_005489017	PREDICTED: DNA topoisomerase 3-beta-1 [Zonotrichia albicollis].	24.41	422	248	14	40	434	297	674	4e-16	91.3
rs:WP_000246609	DNA topoisomerase I [Streptococcus agalactiae].	22.43	437	276	13	34	452	229	620	4e-16	90.9
rs:WP_003678435	DNA topoisomerase I [Lactobacillus coryniformis].	24.94	397	237	15	77	454	256	610	4e-16	90.9
rs:WP_027698447	DNA topoisomerase I [Weissella oryzae].	24.01	429	268	12	41	452	240	627	4e-16	90.9
rs:WP_011640264	DNA topoisomerase I [Syntrophomonas wolfei].	25.17	429	255	14	47	452	224	609	4e-16	90.9
rs:WP_043881503	DNA topoisomerase III, partial [Vibrio cholerae].	40.00	90	54	0	36	125	255	344	4e-16	89.0
rs:WP_015081448	DNA topoisomerase I [Anabaena sp. 90].	25.99	354	227	9	41	387	249	574	4e-16	91.3
rs:WP_034084293	DNA topoisomerase 1 [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	4e-16	91.3
rs:WP_011822082	DNA topoisomerase I [Hyperthermus butylicus].	24.08	382	236	11	60	425	270	613	4e-16	90.9
rs:WP_008735261	topoisomerase I [Alcanivorax pacificus].	26.18	382	233	14	77	446	295	639	4e-16	91.3
rs:WP_008283969	DNA topoisomerase I [gamma proteobacterium HTCC5015].	26.57	414	242	16	61	452	248	621	4e-16	91.3
rs:WP_045685654	DNA topoisomerase I [Martelella endophytica].	26.13	444	241	19	54	452	237	638	4e-16	91.3
rs:WP_014624573	DNA topoisomerase I [Spirochaeta thermophila].	25.53	427	255	16	47	454	235	617	5e-16	90.9
rs:WP_016480750	DNA topoisomerase I [Streptococcus agalactiae].	22.65	437	275	14	34	452	229	620	5e-16	90.9
rs:WP_036093842	DNA topoisomerase I [Listeria newyorkensis].	23.71	426	268	14	50	457	227	613	5e-16	90.9
rs:WP_018371247	DNA topoisomerase I [Streptococcus massiliensis].	24.38	402	245	12	66	452	253	610	5e-16	90.9
rs:WP_013875453	DNA topoisomerase I [Frankia symbiont of Datisca glomerata].	28.42	366	202	14	39	387	351	673	5e-16	91.3
rs:XP_006938803	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Felis catus].	24.27	342	200	10	40	362	263	564	5e-16	91.3
tr:H1PLC7_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.62	463	250	15	48	453	241	661	5e-16	90.9
tr:A0A0D0I5I6_BACTM	SubName: Full=Bacillus thuringiensis serovar morrisoni strain HD 600 BG10.Contig244, whole genome shotgun sequence {ECO:0000313|EMBL:KIP25088.1};	37.21	129	77	2	276	401	5	132	5e-16	87.8
rs:WP_002257107	DNA topoisomerase I [Neisseria meningitidis].	24.02	483	262	14	43	454	228	676	5e-16	90.9
rs:WP_011968523	DNA topoisomerase I [Clostridium beijerinckii].	23.96	409	249	13	66	454	242	608	5e-16	90.9
rs:WP_025820579	DNA topoisomerase I [Shewanella marina].	26.46	412	249	16	47	446	262	631	5e-16	91.3
tr:A0A0B8NL35_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	40.82	98	58	0	35	132	202	299	5e-16	88.2
tr:A0A0B2W574_TOXCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.40	356	222	10	40	388	341	663	5e-16	91.3
rs:WP_000246607	DNA topoisomerase I [Streptococcus agalactiae].	22.65	437	275	14	34	452	229	620	5e-16	90.9
rs:WP_034508708	DNA topoisomerase I [Agrobacterium rhizogenes].	26.13	444	256	15	47	452	230	639	5e-16	91.3
rs:WP_021392297	DNA topoisomerase I [Peptoclostridium difficile].	21.56	436	283	10	36	454	215	608	5e-16	90.9
rs:WP_014343771	DNA topoisomerase III [Aliivibrio fischeri].	37.98	129	80	0	293	421	1	129	5e-16	87.0
rs:WP_047164149	DNA topoisomerase I [Trichodesmium erythraeum].	25.45	393	241	11	30	398	235	599	5e-16	91.3
rs:WP_043102403	DNA topoisomerase I [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	5e-16	91.3
rs:WP_046106690	DNA topoisomerase I [Devosia geojensis].	25.81	434	268	15	43	452	226	629	5e-16	91.3
rs:XP_008922043	PREDICTED: DNA topoisomerase 3-beta-1 [Manacus vitellinus].	24.43	438	259	15	25	434	222	615	5e-16	91.3
rs:WP_010844242	DNA topoisomerase I subunit omega [Gordonia terrae].	26.01	396	239	13	37	409	262	626	5e-16	91.3
rs:WP_028576602	DNA topoisomerase I [Desulfomicrobium escambiense].	25.47	424	263	12	43	452	221	605	5e-16	90.9
tr:E7G433_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.48	429	259	14	41	450	252	634	5e-16	90.9
rs:WP_000246608	DNA topoisomerase I [Streptococcus agalactiae].	22.65	437	275	14	34	452	229	620	5e-16	90.9
rs:WP_034533897	DNA topoisomerase I [Lactobacillus kunkeei].	25.43	405	241	15	65	452	259	619	5e-16	90.9
rs:WP_029940950	DNA topoisomerase I, partial [Sphingomonas astaxanthinifaciens].	26.62	402	238	14	71	452	252	616	5e-16	90.9
rs:WP_028659797	DNA topoisomerase I [Nocardioides insulae].	27.70	361	215	13	42	387	256	585	5e-16	91.3
rs:WP_004848998	DNA topoisomerase I [Coprococcus eutactus].	23.94	426	269	12	45	454	224	610	5e-16	90.9
rs:WP_021163353	DNA topoisomerase III in PFGI-1-like cluster [Burkholderia phytofirmans].	38.68	106	65	0	127	232	3	108	5e-16	85.5
rs:WP_013028145	DNA topoisomerase I [Sideroxydans lithotrophicus].	23.57	471	290	14	3	452	195	616	5e-16	91.3
tr:A0A0E9EGE3_CHLTH	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CRH69591.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRH69591.1};	25.43	409	246	14	66	457	246	612	5e-16	90.9
rs:WP_008902384	DNA topoisomerase I [Peptoniphilus duerdenii].	25.06	411	242	14	65	456	247	610	5e-16	90.9
rs:WP_002503404	DNA topoisomerase I [Staphylococcus epidermidis].	23.70	422	261	14	50	452	227	606	5e-16	90.9
rs:WP_031824418	DNA topoisomerase I [Staphylococcus aureus].	24.42	434	249	19	47	452	224	606	5e-16	90.9
rs:WP_015117455	DNA topoisomerase I [Rivularia sp. PCC 7116].	24.44	405	252	11	40	429	241	606	5e-16	90.9
rs:WP_031277332	DNA topoisomerase I [Pseudomonas aeruginosa].	25.37	410	243	13	74	459	260	630	5e-16	90.9
rs:WP_020650998	DNA topoisomerase I [Solimonas variicoloris].	27.62	391	216	14	24	377	201	561	5e-16	90.9
rs:WP_020949217	DNA topoisomerase I [Paracoccus aminophilus].	25.87	429	257	13	51	454	233	625	5e-16	91.3
rs:WP_033539235	DNA topoisomerase I [Shewanella sp. ECSMB14101].	25.40	378	236	12	77	446	292	631	5e-16	90.9
rs:WP_040443079	DNA topoisomerase I, partial [Ktedonobacter racemifer].	22.44	459	258	15	47	449	253	669	5e-16	90.9
rs:WP_002224768	DNA topoisomerase I [Neisseria meningitidis].	24.02	483	262	14	43	454	228	676	5e-16	90.9
rs:WP_037433360	DNA topoisomerase I, partial [Sinorhizobium fredii].	25.23	440	264	14	47	452	3	411	5e-16	90.9
tr:A0A093PVT6_9PASS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.43	438	259	15	25	434	224	617	5e-16	90.9
rs:XP_002090715	GE13263 [Drosophila yakuba].	24.83	447	265	14	39	451	255	664	5e-16	91.3
rs:WP_004520185	MULTISPECIES: DNA topoisomerase I [Neisseria].	23.54	480	268	10	43	454	228	676	5e-16	90.9
rs:WP_040504074	hypothetical protein, partial [Leucothrix mucor].	26.72	408	226	17	50	416	244	619	5e-16	90.9
rs:WP_046306847	DNA topoisomerase I [Lactobacillus apis].	23.65	427	266	12	43	452	230	613	5e-16	90.9
rs:WP_006286687	topoisomerase IA [Paenibacillus popilliae].	24.77	440	265	14	41	457	218	614	5e-16	90.9
rs:WP_041705892	DNA topoisomerase I, partial [Mageeibacillus indolicus].	25.00	452	275	14	23	452	203	612	5e-16	90.9
rs:WP_013585761	DNA topoisomerase I [Microbacterium testaceum].	29.31	348	194	13	44	377	266	575	5e-16	90.9
rs:WP_024525219	DNA topoisomerase I [Lactobacillus brevis].	25.28	439	259	15	41	457	234	625	5e-16	90.9
rs:WP_034449286	DNA topoisomerase I [Bartonella quintana].	26.95	423	238	18	67	452	248	636	5e-16	90.9
rs:XP_009622052	PREDICTED: DNA topoisomerase 3-alpha isoform X4 [Nicotiana tomentosiformis].	25.00	468	270	17	18	447	248	672	5e-16	90.9
rs:WP_046159897	DNA topoisomerase I [Caldanaerobacter subterraneus].	26.52	411	239	14	69	457	247	616	5e-16	90.9
rs:WP_009782287	DNA topoisomerase I [Lyngbya sp. PCC 8106].	26.18	401	238	12	25	398	230	599	5e-16	90.9
rs:WP_028735946	DNA topoisomerase I [Rhizobium selenitireducens].	27.40	416	239	14	70	452	253	638	5e-16	90.9
tr:H5V9T9_HELBI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.48	433	261	12	41	454	245	630	5e-16	90.9
tr:A0A060QAM0_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.71	429	268	12	54	454	240	641	5e-16	90.9
rs:WP_015058546	DNA topoisomerase I [Streptococcus agalactiae].	22.43	437	276	13	34	452	229	620	5e-16	90.9
rs:WP_025324779	DNA topoisomerase I [Pseudomonas aeruginosa].	25.85	410	241	13	74	459	260	630	5e-16	90.5
rs:WP_033977639	DNA topoisomerase 1 [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	5e-16	90.9
rs:WP_046538212	DNA topoisomerase I [Clostridiales bacterium PH28_bin88].	25.59	426	262	13	50	457	234	622	5e-16	90.9
rs:WP_044215064	DNA topoisomerase I, partial [Candidatus Endolissoclinum faulkneri].	25.17	437	268	14	47	452	231	639	5e-16	90.9
tr:R7VCK8_CAPTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.43	414	263	12	40	434	258	636	5e-16	90.9
rs:WP_020303003	DNA topoisomerase I [Pseudomonas sp. CF150].	24.69	401	260	12	70	459	256	625	5e-16	90.5
rs:WP_022483769	DNA topoisomerase [Clostridium sp. CAG:389].	23.88	423	269	11	47	454	226	610	5e-16	90.9
rs:WP_014738751	DNA topoisomerase I [Modestobacter marinus].	27.52	327	195	10	42	354	283	581	5e-16	90.9
rs:WP_043561693	DNA topoisomerase I [Saccharibacter sp. AM169].	25.41	429	265	12	54	454	238	639	5e-16	90.9
rs:WP_006330915	DNA topoisomerase I [Gordonia rhizosphera].	27.04	355	210	11	41	377	270	593	5e-16	90.9
rs:WP_039620968	DNA topoisomerase I [Acinetobacter harbinensis].	25.31	320	201	8	40	356	267	551	5e-16	90.9
rs:WP_044329464	DNA topoisomerase I [Mycoplasma hominis].	24.40	377	213	13	92	450	271	593	5e-16	90.5
rs:WP_026187416	DNA topoisomerase I [Ensifer sp. BR816].	25.11	438	267	13	47	452	230	638	5e-16	90.9
rs:WP_022502718	DNA topoisomerase [Eubacterium sp. CAG:76].	24.29	420	263	11	54	457	233	613	5e-16	90.9
rs:WP_028463728	DNA topoisomerase I [Nocardia sp. 348MFTsu5.1].	25.75	365	222	10	41	387	265	598	5e-16	90.9
rs:XP_001095437	PREDICTED: DNA topoisomerase 3-alpha [Macaca mulatta].	25.75	400	231	13	77	450	302	661	5e-16	90.9
rs:XP_009510457	PREDICTED: DNA topoisomerase 3-beta-1, partial [Phalacrocorax carbo].	24.41	422	248	14	40	434	254	631	5e-16	90.9
rs:WP_033995540	DNA topoisomerase I [Pseudomonas aeruginosa].	24.82	411	244	13	74	459	260	630	5e-16	90.5
rs:XP_004381056	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Trichechus manatus latirostris].	24.76	424	251	14	60	455	215	598	5e-16	90.9
rs:WP_047146216	DNA topoisomerase I [Mesorhizobium sp. LC103].	25.18	413	243	15	70	449	253	632	5e-16	90.9
rs:WP_011959681	topoisomerase I [Psychrobacter sp. PRwf-1].	27.69	437	238	23	40	452	269	651	6e-16	90.9
rs:WP_026095613	DNA topoisomerase I [Microbacterium sp. B19].	28.39	317	179	10	77	377	289	573	6e-16	90.9
tr:V8EN21_PSEAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.37	410	243	13	74	459	212	582	6e-16	90.5
rs:XP_008227548	PREDICTED: DNA topoisomerase 3-alpha [Prunus mume].	24.55	440	272	12	39	452	261	666	6e-16	90.9
rs:WP_031891318	DNA topoisomerase 1 [Staphylococcus aureus].	24.24	429	256	18	47	452	224	606	6e-16	90.9
rs:WP_017909761	DNA topoisomerase I [Xanthomonas sp. SHU199].	30.23	301	164	12	66	350	254	524	6e-16	90.9
rs:WP_031596742	DNA topoisomerase I, partial [Ferrovum myxofaciens].	24.16	418	270	14	51	452	233	619	6e-16	90.9
rs:WP_031943396	DNA topoisomerase I [uncultured bacterium].	26.05	403	249	14	70	459	252	618	6e-16	90.5
tr:D3R1W8_MAGIU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	452	275	14	23	452	203	612	6e-16	90.9
tr:W7CHH1_9LIST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	23.47	426	269	14	50	457	16	402	6e-16	90.1
rs:WP_024301152	DNA topoisomerase I [Pseudogulbenkiania sp. MAI-1].	24.09	494	271	15	31	459	221	675	6e-16	90.9
rs:WP_006564301	DNA topoisomerase I [Helicobacter suis].	24.48	429	259	14	41	450	252	634	6e-16	90.9
rs:WP_019144471	DNA topoisomerase I [Aeromicrobium massiliense].	27.58	330	190	12	42	356	252	547	6e-16	90.9
rs:WP_025489727	DNA topoisomerase I [Clostridiales bacterium VE202-27].	25.13	398	242	11	74	454	255	613	6e-16	90.5
rs:WP_021689324	DNA topoisomerase I [Novosphingobium tardaugens].	27.29	469	261	19	22	452	192	618	6e-16	90.9
rs:WP_039772254	DNA topoisomerase I [Clostridium diolis].	24.33	411	245	14	66	454	242	608	6e-16	90.5
rs:WP_043156147	DNA topoisomerase I [Pseudomonas aeruginosa].	25.32	391	241	12	68	446	274	625	6e-16	90.9
rs:WP_023105002	DNA topoisomerase I [Pseudomonas aeruginosa].	25.06	411	243	13	74	459	260	630	6e-16	90.5
rs:WP_017163892	DNA topoisomerase I, partial [Xanthomonas axonopodis].	29.02	379	208	16	66	413	148	496	6e-16	90.9
tr:G6DDL0_DANPL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.98	358	217	10	40	388	258	576	6e-16	90.9
rs:WP_002891063	DNA topoisomerase I [Streptococcus salivarius].	24.04	441	263	15	34	452	238	628	6e-16	90.5
rs:WP_022132257	DNA topoisomerase [Clostridium sp. CAG:242].	24.82	427	259	16	47	452	281	666	6e-16	90.9
rs:WP_022212330	DNA topoisomerase [Clostridium sp. CAG:265].	25.51	439	236	17	66	449	242	644	6e-16	90.5
tr:K2EQJ2_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EKE07914.1}; Flags: Fragment;	26.64	304	176	10	166	454	6	277	6e-16	90.1
rs:WP_022775098	hypothetical protein [Butyrivibrio sp. AE2015].	26.76	370	234	15	70	426	274	619	6e-16	90.5
rs:WP_031637565	DNA topoisomerase I [Pseudomonas aeruginosa].	25.85	410	241	13	74	459	260	630	6e-16	90.5
rs:WP_039223928	DNA topoisomerase I [Alteromonas marina].	26.05	453	260	16	8	446	239	630	6e-16	90.9
tr:W6FUY3_NODSP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.13	378	235	10	41	401	220	566	6e-16	90.9
rs:WP_004317674	DNA topoisomerase I [Campylobacter concisus].	26.90	394	220	16	77	450	254	599	6e-16	90.5
rs:WP_048041569	DNA topoisomerase [Methanosarcina mazei].	24.39	451	263	17	34	453	238	641	6e-16	90.9
rs:WP_026846612	DNA topoisomerase I [Geodermatophilaceae bacterium URHA0031].	27.52	327	195	10	42	354	283	581	6e-16	90.9
rs:WP_019124724	DNA topoisomerase I [Peptoniphilus grossensis].	23.76	425	265	13	47	454	228	610	6e-16	90.5
rs:WP_021635915	DNA topoisomerase I [Clostridium sp. KLE 1755].	25.13	398	242	11	74	454	255	613	6e-16	90.5
rs:WP_006197444	DNA topoisomerase I [Nodularia spumigena].	25.13	378	235	10	41	401	249	595	6e-16	90.9
rs:WP_015769353	DNA topoisomerase I [Leptotrichia buccalis].	26.92	338	190	11	60	379	234	532	6e-16	90.9
rs:WP_019780742	hypothetical protein, partial [Streptococcus sobrinus].	26.10	341	207	11	71	404	250	552	6e-16	90.5
tr:A0A0F2QAH5_9CLOT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJS23503.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KJS23503.1};	26.35	406	241	12	71	458	249	614	6e-16	90.5
rs:WP_046272835	DNA topoisomerase I [Stenotrophomonas maltophilia].	30.13	302	164	12	66	350	254	525	6e-16	90.9
rs:XP_012363345	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-beta-1 [Nomascus leucogenys].	23.01	439	271	15	25	438	222	618	6e-16	90.9
tr:A0A0A6PH49_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.78	407	235	16	69	452	255	621	6e-16	90.9
tr:E1MAK9_9STRE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.13	386	222	13	86	452	3	340	6e-16	89.7
rs:WP_026182515	DNA topoisomerase I [Leeia oryzae].	25.17	433	275	12	31	452	221	615	6e-16	90.9
rs:WP_033987969	DNA topoisomerase I [Pseudomonas aeruginosa].	25.30	411	242	14	74	459	260	630	6e-16	90.5
rs:WP_023605764	DNA topoisomerase 1 [Vagococcus lutrae].	24.34	419	252	15	61	457	239	614	6e-16	90.5
rs:WP_028098167	DNA topoisomerase I [Dongia sp. URHE0060].	26.29	445	252	16	58	454	242	658	6e-16	90.9
rs:WP_006735030	MULTISPECIES: DNA topoisomerase I [Lactobacillus].	22.50	480	300	15	1	452	175	610	6e-16	90.5
rs:WP_039671403	DNA topoisomerase [Streptococcus macedonicus].	27.83	327	180	12	74	385	278	563	6e-16	90.5
rs:WP_015113376	DNA topoisomerase I [Nostoc sp. PCC 7107].	25.13	378	235	10	41	401	249	595	6e-16	90.9
rs:WP_002436312	DNA topoisomerase I [Staphylococcus capitis].	22.82	425	267	14	47	452	224	606	6e-16	90.5
rs:WP_039836543	DNA topoisomerase I [Paenibacillus sonchi].	24.65	434	255	15	50	457	227	614	6e-16	90.5
rs:WP_010619796	DNA topoisomerase I [Lactobacillus malefermentans].	25.72	416	246	17	55	452	246	616	6e-16	90.5
rs:WP_022289901	DNA topoisomerase [Oscillibacter sp. CAG:155].	26.42	439	256	14	47	459	228	625	6e-16	90.9
rs:WP_005556886	topoisomerase I [Aggregatibacter actinomycetemcomitans].	23.94	376	243	11	77	446	290	628	6e-16	90.9
rs:WP_040361669	DNA topoisomerase I [Corynebacterium amycolatum].	25.14	362	228	9	40	386	261	594	6e-16	90.9
rs:WP_007312723	DNA topoisomerase I, partial [Crocosphaera watsonii].	25.00	436	258	13	25	436	216	606	6e-16	90.5
rs:WP_027259853	DNA topoisomerase I [Leisingera aquimarina].	25.33	458	263	17	41	454	225	647	6e-16	90.9
rs:WP_041900725	hypothetical protein, partial [Marinimicrobia bacterium SCGC AAA160-B08].	25.35	359	222	11	41	392	241	560	6e-16	90.9
rs:WP_016876994	DNA topoisomerase I [Chlorogloeopsis fritschii].	26.07	349	217	9	41	379	255	572	6e-16	90.9
rs:WP_017173006	DNA topoisomerase I, partial [Xanthomonas axonopodis].	29.02	379	208	16	66	413	254	602	6e-16	90.9
rs:WP_035922521	DNA topoisomerase I, partial [Kordiimonas gwangyangensis].	25.11	450	262	15	41	454	224	634	6e-16	90.9
rs:WP_046939159	DNA topoisomerase I [Haemophilus haemolyticus].	25.86	379	232	14	77	446	290	628	6e-16	90.9
rs:WP_018669350	DNA topoisomerase I [Bacteroides gallinarum].	26.82	302	179	8	40	334	216	482	6e-16	90.5
rs:WP_018589680	DNA topoisomerase I [Terrisporobacter glycolicus].	22.54	426	269	11	47	454	226	608	6e-16	90.5
rs:WP_020098197	DNA topoisomerase I [Microbacterium sp. 11MF].	28.91	339	193	13	51	377	269	571	6e-16	90.9
rs:WP_048043045	DNA topoisomerase [Methanosarcina mazei].	24.39	451	263	17	34	453	238	641	6e-16	90.9
rs:WP_005200284	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	26.29	426	259	18	40	452	267	650	6e-16	90.9
tr:V9TUY8_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.17	437	268	14	47	452	231	639	6e-16	90.9
rs:WP_037258583	DNA topoisomerase I [Roseivivax halodurans].	25.73	478	255	17	41	454	225	666	6e-16	90.9
rs:WP_006280185	MULTISPECIES: DNA topoisomerase I [Wolbachia].	25.34	442	252	15	47	452	231	630	6e-16	90.5
rs:WP_040277260	DNA topoisomerase I [Xanthomonas citri].	29.02	379	208	16	66	413	254	602	6e-16	90.9
rs:WP_014130772	DNA topoisomerase I [Pelagibacterium halotolerans].	26.64	428	260	14	47	452	230	625	6e-16	90.9
rs:WP_035709424	DNA topoisomerase I [Haematobacter massiliensis].	25.69	436	257	14	47	454	228	624	6e-16	90.9
rs:WP_018233248	DNA topoisomerase I [Thioalkalivibrio thiocyanodenitrificans].	27.97	311	192	7	48	350	236	522	6e-16	90.5
rs:WP_047207279	DNA topoisomerase I [Streptococcus agalactiae].	22.43	437	276	13	34	452	229	620	6e-16	90.5
rs:WP_033997592	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	25.61	410	242	13	74	459	97	467	6e-16	90.1
rs:XP_008667766	PREDICTED: hypothetical protein isoform X4 [Zea mays].	24.57	460	277	15	24	452	154	574	6e-16	90.5
rs:WP_008885444	DNA topoisomerase I [Citreicella sp. SE45].	26.27	472	246	17	47	454	231	664	6e-16	90.9
rs:WP_015410922	DNA topoisomerase I [Methanosarcina mazei].	24.39	451	263	17	34	453	238	641	6e-16	90.5
rs:WP_042838739	DNA topoisomerase I [Xanthomonas citri].	28.91	377	211	16	66	413	254	602	6e-16	90.5
rs:WP_028108824	DNA topoisomerase I [Ferrimonas futtsuensis].	26.60	312	183	6	51	354	267	540	6e-16	90.9
rs:WP_024090959	DNA topoisomerase I [Leisingera methylohalidivorans].	25.43	460	260	18	41	454	225	647	6e-16	90.9
rs:WP_007221678	DNA topoisomerase I [Candidatus Jettenia caeni].	25.12	430	263	15	47	458	236	624	6e-16	90.5
rs:XP_004088632	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-beta-1 [Nomascus leucogenys].	23.01	439	271	15	25	438	203	599	7e-16	90.5
rs:WP_002812072	DNA topoisomerase I [Nitrosococcus oceani].	27.61	373	210	11	33	377	221	561	7e-16	90.5
rs:WP_003521492	DNA topoisomerase I subunit omega [Agrobacterium tumefaciens].	25.79	442	259	15	47	452	230	638	7e-16	90.9
rs:WP_017296559	hypothetical protein [Nodosilinea nodulosa].	24.72	445	248	16	31	436	224	620	7e-16	90.5
rs:WP_018066740	DNA topoisomerase I [Martelella mediterranea].	25.57	442	246	16	54	452	237	638	7e-16	90.5
rs:WP_014620285	DNA topoisomerase III [Streptococcus gallolyticus].	27.19	320	191	12	74	385	278	563	7e-16	90.1
rs:WP_034581636	DNA topoisomerase I [Helicobacter bizzozeronii].	24.48	433	261	12	41	454	247	632	7e-16	90.5
rs:WP_023275865	DNA topoisomerase I [Mucispirillum schaedleri].	25.31	403	258	11	61	452	244	614	7e-16	90.5
rs:WP_028117526	DNA topoisomerase I [Ferrimonas senticii].	24.82	427	268	16	40	452	257	644	7e-16	90.5
rs:WP_048049877	DNA topoisomerase [Methanosarcina mazei].	24.39	451	263	17	34	453	238	641	7e-16	90.5
rs:WP_038587908	DNA topoisomerase I [Corynebacterium imitans].	24.85	338	203	9	30	354	246	545	7e-16	90.9
rs:WP_043038965	DNA topoisomerase I [Streptococcus equi].	23.56	416	242	13	61	452	262	625	7e-16	90.5
rs:WP_032090097	DNA topoisomerase I [bacterium LF-3].	26.28	392	224	12	77	450	255	599	7e-16	90.5
rs:WP_046434318	DNA topoisomerase I [Ruminococcus sp. UNK.MGS-30].	25.23	432	258	17	43	452	224	612	7e-16	90.5
rs:XP_012682632	PREDICTED: DNA topoisomerase 3-alpha [Clupea harengus].	24.60	435	267	14	40	450	293	690	7e-16	90.9
rs:WP_000246612	DNA topoisomerase I [Streptococcus agalactiae].	22.43	437	276	13	34	452	229	620	7e-16	90.5
rs:WP_032139562	DNA topoisomerase I [Rickettsia tamurae].	25.24	420	237	17	65	449	250	627	7e-16	90.5
rs:XP_012499599	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Propithecus coquereli].	23.63	457	268	17	25	453	316	719	7e-16	90.5
rs:WP_016408454	DNA topoisomerase [Firmicutes bacterium CAG:102].	23.92	439	269	14	36	454	242	635	7e-16	90.5
tr:H3CL93_TETNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.65	460	277	16	24	455	240	662	7e-16	90.5
rs:WP_011747004	DNA topoisomerase I [Paracoccus denitrificans].	24.94	429	261	14	51	454	233	625	7e-16	90.5
rs:WP_042823960	DNA topoisomerase I [Xanthomonas axonopodis].	29.00	369	206	15	66	408	254	592	7e-16	90.5
rs:WP_003123327	DNA topoisomerase I [Pseudomonas aeruginosa].	25.55	411	241	14	74	459	260	630	7e-16	90.5
rs:WP_019183580	DNA topoisomerase I [Stenotrophomonas maltophilia].	30.13	302	164	12	66	350	254	525	7e-16	90.5
rs:WP_024585500	DNA topoisomerase I [Aliihoeflea sp. 2WW].	26.19	443	261	16	41	449	224	634	7e-16	90.5
rs:WP_047207619	DNA topoisomerase I [Mycoplasma hominis].	24.40	377	213	13	92	450	271	593	7e-16	90.1
rs:WP_017542879	DNA topoisomerase I [Nocardiopsis prasina].	26.87	361	214	11	36	379	271	598	7e-16	90.5
rs:WP_019910391	DNA topoisomerase I [Paenibacillus sp. HW567].	24.65	430	260	15	50	457	227	614	7e-16	90.5
rs:WP_021236287	DNA topoisomerase I [Novosphingobium lindaniclasticum].	26.30	422	254	13	52	452	233	618	7e-16	90.5
rs:WP_002290910	DNA topoisomerase I [Streptococcus mutans].	24.05	420	257	13	50	452	245	619	7e-16	90.5
tr:F3PJ55_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.58	316	181	8	36	334	224	505	7e-16	90.5
tr:T2J8Q9_CROWT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.77	436	259	13	25	436	216	606	7e-16	90.5
rs:WP_006020922	DNA topoisomerase I [Afipia broomeae].	25.41	429	252	14	60	454	243	637	7e-16	90.5
rs:WP_014509854	DNA topoisomerase I [Thermus thermophilus].	26.57	414	229	15	61	454	264	622	7e-16	90.5
tr:K2EGY6_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.19	445	268	14	13	452	194	587	7e-16	90.1
rs:WP_015415282	DNA topoisomerase 1 [Desulfovibrio piezophilus].	24.69	401	243	13	66	450	248	605	7e-16	90.5
rs:WP_005927347	DNA topoisomerase I [Xanthomonas axonopodis].	29.02	379	208	16	66	413	254	602	7e-16	90.5
rs:WP_011348788	MULTISPECIES: DNA topoisomerase I [Xanthomonas].	29.02	379	208	16	66	413	254	602	7e-16	90.5
rs:WP_028539393	DNA topoisomerase I [Paenibacillus sp. J14].	25.12	414	248	17	66	457	242	615	7e-16	90.5
rs:XP_008667757	PREDICTED: hypothetical protein isoform X2 [Zea mays].	24.57	460	277	15	24	452	251	671	7e-16	90.5
rs:WP_018365968	DNA topoisomerase I [Streptococcus didelphis].	22.25	427	256	13	50	452	255	629	7e-16	90.5
rs:WP_022484853	DNA topoisomerase [Fusobacterium sp. CAG:815].	23.10	394	249	13	77	452	271	628	7e-16	90.5
rs:WP_005921909	DNA topoisomerase I [Xanthomonas axonopodis].	29.02	379	208	16	66	413	242	590	7e-16	90.5
rs:WP_021886309	DNA topoisomerase [Clostridium sp. CAG:590].	23.58	424	267	12	48	454	227	610	7e-16	90.5
rs:WP_023102685	DNA topoisomerase I [Pseudomonas aeruginosa].	24.94	405	251	13	74	459	260	630	7e-16	90.1
rs:WP_040343002	DNA topoisomerase III, partial [Bacillus nealsonii].	27.68	271	151	8	170	434	20	251	7e-16	88.6
rs:WP_039579585	DNA topoisomerase I [Xanthomonas axonopodis].	29.02	379	208	16	66	413	254	602	7e-16	90.5
rs:XP_002079938	GD24215 [Drosophila simulans].	24.72	449	267	16	37	451	253	664	7e-16	90.5
rs:WP_018187056	DNA topoisomerase I [Microbacterium paraoxydans].	28.91	339	193	13	51	377	269	571	7e-16	90.5
rs:XP_008958124	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Pan paniscus].	25.14	358	208	11	25	362	247	564	7e-16	90.5
rs:WP_005911395	MULTISPECIES: DNA topoisomerase I [Xanthomonas].	29.02	379	208	16	66	413	254	602	7e-16	90.5
rs:WP_014504887	DNA topoisomerase I [Xanthomonas oryzae].	28.50	379	210	16	66	413	254	602	7e-16	90.5
rs:WP_024711277	DNA topoisomerase I [Xanthomonas oryzae].	28.50	379	210	16	66	413	254	602	7e-16	90.5
tr:C4K2S3_RICPU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.54	415	242	16	65	449	250	627	7e-16	90.5
rs:WP_019778497	hypothetical protein [Streptococcus sobrinus].	26.18	340	206	11	71	403	276	577	7e-16	90.1
rs:WP_031233433	DNA topoisomerase I [Agrobacterium tumefaciens].	25.79	442	259	15	47	452	230	638	7e-16	90.5
rs:WP_029820479	DNA topoisomerase I [Xanthomonas alfalfae].	29.02	379	208	16	66	413	254	602	7e-16	90.5
rs:WP_047811191	DNA topoisomerase I [Desulfosporosinus acididurans].	25.81	434	262	16	45	457	222	616	7e-16	90.5
rs:WP_010373951	MULTISPECIES: topoisomerase I [Pseudoalteromonas].	25.42	417	257	15	42	446	257	631	8e-16	90.5
rs:WP_034344388	DNA topoisomerase I [Deinococcus misasensis].	26.81	317	194	7	36	344	246	532	8e-16	90.5
rs:WP_048484982	DNA topoisomerase I [Xanthomonas oryzae].	28.50	379	210	16	66	413	254	602	8e-16	90.5
tr:A0A077UHQ3_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.76	425	263	15	47	452	226	608	8e-16	90.1
rs:XP_008667755	PREDICTED: hypothetical protein isoform X1 [Zea mays].	24.57	460	277	15	24	452	251	671	8e-16	90.5
rs:WP_017650225	DNA topoisomerase I [Streptococcus agalactiae].	22.62	442	269	14	34	452	229	620	8e-16	90.1
rs:WP_003484458	DNA topoisomerase I [Xanthomonas citri].	29.02	379	208	16	66	413	254	602	8e-16	90.5
rs:XP_009436163	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Pan troglodytes].	25.14	358	208	11	25	362	247	564	8e-16	90.5
rs:XP_009922297	PREDICTED: DNA topoisomerase 3-beta-1, partial [Haliaeetus albicilla].	23.52	438	263	14	25	434	144	537	8e-16	90.5
tr:K6XNM9_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.23	385	231	12	47	409	254	607	8e-16	90.5
rs:WP_047425144	DNA topoisomerase I [Staphylococcus aureus].	23.76	425	263	15	47	452	224	606	8e-16	90.1
rs:WP_023124573	DNA topoisomerase I [Pseudomonas aeruginosa].	25.37	410	243	13	74	459	260	630	8e-16	90.1
rs:WP_038305813	DNA topoisomerase I [Kingella kingae].	25.21	484	261	14	41	454	227	679	8e-16	90.5
rs:WP_016850507	DNA topoisomerase I [Xanthomonas axonopodis].	29.02	379	208	16	66	413	254	602	8e-16	90.5
rs:WP_023058511	MULTISPECIES: DNA topoisomerase I [Prevotella].	26.42	318	198	9	22	334	196	482	8e-16	90.5
rs:WP_043053080	DNA topoisomerase I [Streptococcus equi].	23.56	416	242	13	61	452	262	625	8e-16	90.1
rs:WP_022608758	DNA topoisomerase I [Rubidibacter lacunae].	27.03	344	216	9	41	377	249	564	8e-16	90.5
rs:WP_020075496	DNA topoisomerase I [Cryocola sp. 340MFSha3.1].	27.86	341	203	11	30	354	238	551	8e-16	90.5
rs:WP_039950861	DNA topoisomerase I [Bacteroides clarus].	26.58	316	181	8	36	334	201	482	8e-16	90.5
rs:WP_035088805	DNA topoisomerase I [Devosia sp. 17-2-E-8].	26.23	427	265	13	47	452	230	627	8e-16	90.5
rs:WP_016312454	DNA topoisomerase I [Paenibacillus barengoltzii].	25.12	414	248	17	66	457	242	615	8e-16	90.1
rs:WP_017813666	DNA topoisomerase I [Paenibacillus sp. A9].	22.97	431	272	14	47	457	224	614	8e-16	90.1
rs:WP_029146385	DNA topoisomerase I [Microbacterium luticocti].	30.09	319	172	13	48	354	266	545	8e-16	90.5
rs:WP_034026384	DNA topoisomerase I [Pseudomonas aeruginosa].	24.82	411	244	13	74	459	260	630	8e-16	90.1
rs:WP_003538227	DNA topoisomerase I [Erysipelatoclostridium ramosum].	25.12	434	247	14	44	455	227	604	8e-16	90.1
rs:WP_011052536	DNA topoisomerase I [Xanthomonas citri].	29.02	379	208	16	66	413	254	602	8e-16	90.5
rs:WP_007797415	DNA topoisomerase I [Pelagibaca bermudensis].	27.43	463	243	17	47	454	231	655	8e-16	90.5
rs:XP_010875238	PREDICTED: DNA topoisomerase 3-beta-1, partial [Esox lucius].	23.46	422	252	13	40	434	263	640	8e-16	90.5
rs:WP_045804530	DNA topoisomerase I [Ehrlichia muris].	25.11	442	253	13	47	452	232	631	8e-16	90.5
rs:WP_005641907	topoisomerase I [Haemophilus haemolyticus].	25.86	379	232	14	77	446	290	628	8e-16	90.5
rs:WP_039228825	MULTISPECIES: DNA topoisomerase I [Clostridium].	25.00	416	234	18	66	454	244	608	8e-16	90.1
rs:WP_046831928	DNA topoisomerase I [Xanthomonas axonopodis].	27.44	430	257	18	38	459	215	597	8e-16	90.1
rs:WP_034030652	DNA topoisomerase I [Pseudomonas aeruginosa].	25.37	410	243	13	74	459	260	630	8e-16	90.1
rs:WP_004839147	DNA topoisomerase I [Anaerococcus vaginalis].	22.92	480	295	15	1	452	170	602	8e-16	90.1
rs:WP_017588254	DNA topoisomerase I [Nocardiopsis ganjiahuensis].	27.17	357	218	10	36	379	271	598	8e-16	90.5
rs:WP_023350396	MULTISPECIES: DNA topoisomerase I [Staphylococcus].	22.82	425	267	14	47	452	224	606	8e-16	90.1
rs:XP_011031137	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Populus euphratica].	23.24	469	285	14	18	451	236	664	8e-16	90.5
tr:D6TIW6_9CHLR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.44	459	258	15	47	449	253	669	8e-16	90.5
rs:WP_018189947	DNA topoisomerase I [Leifsonia sp. 109].	27.86	341	203	11	30	354	238	551	8e-16	90.5
rs:WP_023129305	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	25.61	410	242	13	74	459	260	630	8e-16	90.1
rs:WP_017157050	DNA topoisomerase I [Xanthomonas axonopodis].	29.02	379	208	16	66	413	254	602	8e-16	90.5
sp:TOP3A_DROME	RecName: Full=DNA topoisomerase 3-alpha; EC=5.99.1.2; AltName: Full=DNA topoisomerase III alpha;	24.94	449	266	17	37	451	278	689	8e-16	90.5
rs:WP_045657725	DNA topoisomerase I [Clostridiaceae bacterium BRH_c20a].	26.35	406	241	12	71	458	252	617	8e-16	90.1
rs:WP_027896820	DNA topoisomerase I [Pseudomonas thermotolerans].	25.00	408	259	13	47	446	255	623	8e-16	90.5
rs:WP_044420529	DNA topoisomerase I [Mycoplasma hominis].	24.40	377	213	13	92	450	271	593	8e-16	90.1
rs:WP_034038659	DNA topoisomerase I [Pseudomonas aeruginosa].	25.61	410	242	13	74	459	260	630	8e-16	90.1
rs:WP_033866760	DNA topoisomerase I [Pseudomonas aeruginosa].	25.37	410	243	13	74	459	260	630	8e-16	90.1
rs:WP_048488497	DNA topoisomerase I [Xanthomonas oryzae].	28.50	379	210	16	66	413	254	602	8e-16	90.5
rs:WP_045411980	DNA topoisomerase I [Thermoanaerobacterium saccharolyticum].	26.39	451	254	17	28	454	213	609	8e-16	90.1
rs:WP_022220378	DNA topoisomerase [Coprococcus comes CAG:19].	23.67	414	255	10	65	457	244	617	8e-16	90.1
rs:WP_023132186	DNA topoisomerase I [Pseudomonas aeruginosa].	25.06	411	243	14	74	459	260	630	8e-16	90.1
rs:WP_014091221	DNA topoisomerase I [Xanthomonas alfalfae].	29.02	379	208	16	66	413	254	602	8e-16	90.5
rs:XP_002039125	GM17356 [Drosophila sechellia].	24.72	449	267	16	37	451	253	664	8e-16	90.5
rs:WP_027009875	DNA topoisomerase I [Conchiformibius kuhniae].	27.19	434	252	14	41	452	227	618	8e-16	90.1
rs:WP_019312541	DNA topoisomerase I [Streptococcus mutans].	23.76	442	274	14	29	452	223	619	8e-16	90.1
rs:XP_011031138	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Populus euphratica].	23.24	469	285	14	18	451	236	664	8e-16	90.5
rs:WP_043708385	DNA topoisomerase I [Weissella cibaria].	25.06	439	246	16	43	452	248	632	8e-16	90.1
rs:WP_011940495	DNA topoisomerase I [Geobacter uraniireducens].	25.00	412	244	14	65	454	251	619	8e-16	90.1
tr:I7AUN1_PSEPT	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:AFO46345.1};	27.53	287	172	7	166	446	32	288	8e-16	89.7
rs:WP_024071957	DNA topoisomerase I [Ehrlichia muris].	25.62	441	253	13	47	452	232	632	8e-16	90.5
rs:WP_047332528	DNA topoisomerase I [Mycobacterium sp. EPa45].	26.77	381	226	11	41	399	269	618	8e-16	90.5
rs:WP_002883915	DNA topoisomerase I [Streptococcus salivarius].	24.69	409	237	14	65	452	270	628	8e-16	90.1
rs:WP_043941141	DNA topoisomerase I [Weissella cibaria].	25.06	439	246	16	43	452	248	632	8e-16	90.1
rs:WP_013100547	DNA topoisomerase I [Methanocaldococcus infernus].	26.86	350	207	13	112	452	463	772	8e-16	90.1
rs:WP_040535946	DNA topoisomerase I [Gordonia namibiensis].	26.23	385	231	12	47	409	271	624	8e-16	90.5
rs:WP_005656771	topoisomerase I [Haemophilus influenzae].	26.12	379	231	14	77	446	290	628	8e-16	90.5
rs:WP_008375020	DNA topoisomerase I [Coprococcus comes].	24.02	408	261	10	65	457	244	617	8e-16	90.1
rs:WP_019134346	hypothetical protein [Kallipyga massiliensis].	24.14	435	268	13	34	449	210	601	8e-16	90.1
rs:XP_002527391	prokaryotic DNA topoisomerase, putative, partial [Ricinus communis].	24.34	452	256	13	39	451	263	667	8e-16	90.5
rs:XP_001566225	putative DNA topoisomerase III [Leishmania braziliensis MHOM/BR/75/M2904].	23.99	421	254	14	39	434	252	631	8e-16	90.5
rs:WP_008572030	DNA topoisomerase I [Xanthomonas perforans].	29.02	379	208	16	66	413	254	602	8e-16	90.1
rs:WP_017355382	DNA topoisomerase I [Stenotrophomonas maltophilia].	30.23	301	164	11	66	350	254	524	8e-16	90.1
tr:I8R0U8_9THEO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952}; Flags: Precursor;	26.55	452	255	19	28	454	213	612	9e-16	90.1
rs:WP_019777165	hypothetical protein [Streptococcus sobrinus].	26.10	341	207	11	71	404	276	578	9e-16	90.1
rs:XP_002985109	hypothetical protein SELMODRAFT_121488 [Selaginella moellendorffii].	23.68	456	282	15	28	452	248	668	9e-16	90.1
tr:E1NPC4_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	23.82	424	262	14	46	452	7	386	9e-16	89.7
rs:WP_027236761	DNA topoisomerase I [Leisingera caerulea].	25.76	458	261	18	41	454	225	647	9e-16	90.5
rs:WP_009809315	DNA topoisomerase I [Roseobacter sp. MED193].	26.20	458	259	17	41	454	225	647	9e-16	90.5
rs:WP_024048967	DNA topoisomerase [Negativicoccus succinicivorans].	23.68	435	274	13	36	454	246	638	9e-16	90.1
rs:WP_023102572	DNA topoisomerase I [Pseudomonas aeruginosa].	25.37	410	243	13	74	459	260	630	9e-16	90.1
rs:WP_028893704	hypothetical protein [Syntrophorhabdus aromaticivorans].	26.15	436	259	16	36	451	213	605	9e-16	90.1
tr:E2MXW7_CORAY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.07	383	242	10	40	407	307	659	9e-16	90.5
rs:XP_006814887	PREDICTED: DNA topoisomerase 3-beta-1 [Saccoglossus kowalevskii].	24.21	442	254	17	40	453	261	649	9e-16	90.1
rs:WP_024921477	MULTISPECIES: DNA topoisomerase I [Afipia].	25.78	419	243	14	70	454	253	637	9e-16	90.5
rs:WP_009009111	MULTISPECIES: DNA topoisomerase I [Coprobacillus].	25.12	434	247	14	44	455	227	604	9e-16	90.1
rs:WP_015463664	DNA topoisomerase I [Xanthomonas axonopodis].	29.02	379	208	16	66	413	254	602	9e-16	90.1
rs:WP_019191838	DNA topoisomerase I [Anaerococcus pacaensis].	24.25	400	228	14	77	452	254	602	9e-16	90.1
rs:WP_017914936	DNA topoisomerase I [Xanthomonas sp. SHU308].	30.23	301	164	12	66	350	254	524	9e-16	90.1
rs:WP_048490845	DNA topoisomerase I [Xanthomonas axonopodis].	30.23	301	164	12	66	350	254	524	9e-16	90.1
rs:WP_019790039	DNA topoisomerase I [Streptococcus sobrinus].	23.20	444	264	15	34	452	237	628	9e-16	90.1
rs:WP_010373718	DNA topoisomerase I [Weissella cibaria].	25.06	439	246	16	43	452	248	632	9e-16	90.1
rs:WP_037574670	DNA topoisomerase I [Streptacidiphilus oryzae].	26.18	340	197	12	37	354	251	558	9e-16	90.5
rs:WP_031914761	DNA topoisomerase I [Staphylococcus aureus].	24.48	429	255	18	47	452	224	606	9e-16	90.1
gpu:CP010904_865	DNA topoisomerase 1 [Verrucomicrobia bacterium L21-Fru-AB]	26.81	317	184	10	43	351	245	521	9e-16	90.1
rs:WP_023104979	DNA topoisomerase I [Pseudomonas aeruginosa].	25.37	410	243	13	74	459	260	630	9e-16	90.1
rs:WP_048482970	DNA topoisomerase I [Xanthomonas oryzae].	28.50	379	210	16	66	413	254	602	9e-16	90.1
gp:AF255733_1	DNA topoisomerase III alpha [Drosophila melanogaster]	24.94	449	266	17	37	451	278	689	9e-16	90.5
rs:WP_034598654	DNA topoisomerase I [Desulfosporosinus sp. HMP52].	24.41	426	266	13	48	454	225	613	9e-16	90.1
rs:WP_014621523	DNA topoisomerase I [Streptococcus thermophilus].	24.45	409	238	14	65	452	268	626	9e-16	90.1
rs:WP_005709862	topoisomerase I [Haemophilus paraphrohaemolyticus].	26.51	381	227	16	77	446	290	628	9e-16	90.1
rs:WP_041334940	DNA topoisomerase I, partial [Roseiflexus sp. RS-1].	24.19	492	250	15	47	452	230	684	9e-16	90.1
rs:WP_008595679	DNA topoisomerase I [Nitratireductor pacificus].	25.06	439	263	15	47	452	230	635	9e-16	90.1
rs:WP_014904444	DNA topoisomerase I [Desulfosporosinus meridiei].	24.30	428	264	13	48	454	225	613	9e-16	90.1
rs:WP_039568675	DNA topoisomerase I [Xanthomonas axonopodis].	29.02	379	208	16	66	413	254	602	9e-16	90.1
rs:WP_039095210	DNA topoisomerase I [Kirrobacter mercurialis].	26.88	465	267	15	22	449	194	622	9e-16	90.1
rs:WP_017913294	DNA topoisomerase I [Xanthomonas sp. SHU166].	30.23	301	164	12	66	350	254	524	9e-16	90.1
rs:WP_022008214	DNA topoisomerase [Coprobacillus sp. CAG:183].	25.12	434	247	14	44	455	227	604	9e-16	90.1
rs:WP_038480781	DNA topoisomerase I [Bacillus lehensis].	24.35	423	259	14	50	452	227	608	9e-16	90.1
rs:WP_025577921	DNA topoisomerase III [Blautia wexlerae].	26.97	241	166	6	61	296	249	484	9e-16	89.7
rs:XP_011011406	PREDICTED: DNA topoisomerase 3-alpha-like isoform X1 [Populus euphratica].	23.24	469	285	14	18	451	236	664	9e-16	90.1
rs:WP_014027476	DNA topoisomerase I [Pyrolobus fumarii].	26.15	371	212	11	74	425	283	610	9e-16	90.1
rs:WP_039532272	DNA topoisomerase I [Ruegeria sp. ANG-S4].	25.81	461	260	16	41	454	225	650	9e-16	90.1
rs:WP_012719587	DNA topoisomerase I [Rickettsia africae].	25.30	415	243	16	65	449	250	627	9e-16	90.1
rs:XP_003210910	PREDICTED: DNA topoisomerase 3-beta-1 [Meleagris gallopavo].	23.97	438	261	15	25	434	247	640	9e-16	90.1
rs:WP_037310690	DNA topoisomerase I [Ruegeria halocynthiae].	26.28	468	254	18	41	454	225	655	9e-16	90.1
tr:K1UDR3_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC69636.1}; Flags: Fragment;	30.05	203	133	4	220	421	8	202	9e-16	87.4
rs:WP_046833028	hypothetical protein [Xanthomonas axonopodis].	25.22	456	250	16	60	459	231	651	9e-16	90.1
rs:WP_043094550	DNA topoisomerase I [Xanthomonas sacchari].	30.23	301	164	12	66	350	254	524	9e-16	90.1
rs:WP_037552772	DNA topoisomerase I [Sphingomonas sp. URHD0057].	26.20	416	245	15	60	452	241	617	9e-16	90.1
rs:WP_046964308	DNA topoisomerase I [Xanthomonas pisi].	28.91	377	209	16	66	416	254	597	9e-16	90.1
tr:A0A0E7WZC7_STREE	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CRC77532.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRC77532.1};	23.46	405	245	12	66	452	177	534	9e-16	89.7
rs:WP_020434135	DNA topoisomerase I [Paenibacillus riograndensis].	26.00	427	239	17	62	457	234	614	9e-16	90.1
rs:WP_008791761	DNA topoisomerase I [Coprobacillus sp. 8_2_54BFAA].	25.12	434	247	14	44	455	227	604	9e-16	90.1
rs:WP_015774906	DNA topoisomerase I [Desulfomicrobium baculatum].	23.92	439	276	12	31	452	208	605	9e-16	90.1
rs:WP_006527281	DNA topoisomerase I [Gloeocapsa sp. PCC 73106].	26.21	435	255	16	23	436	218	607	9e-16	90.1
rs:WP_037512036	DNA topoisomerase I [Sphingopyxis sp. LC81].	26.90	420	250	14	54	452	235	618	9e-16	90.1
rs:WP_016297112	DNA topoisomerase I [Lachnospiraceae bacterium M18-1].	26.45	431	253	15	48	457	227	614	9e-16	90.1
rs:WP_004460131	DNA topoisomerase III [Clostridium perfringens].	27.30	370	218	18	98	452	306	639	9e-16	90.1
rs:WP_021088986	DNA topoisomerase I [Campylobacter concisus].	26.90	394	220	16	77	450	254	599	9e-16	90.1
rs:WP_015398003	DNA topoisomerase I [Bartonella australis].	26.51	430	233	18	67	453	248	637	9e-16	90.1
rs:WP_015229361	DNA topoisomerase I [Dactylococcopsis salina].	25.78	353	229	8	41	387	249	574	9e-16	90.1
rs:WP_036479525	DNA topoisomerase I [Myxosarcina sp. GI1].	25.35	359	223	10	41	387	249	574	1e-15	90.1
tr:A0A0D0G883_LACBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	25.06	439	260	15	41	457	103	494	1e-15	89.7
rs:WP_011452790	DNA topoisomerase I [Ehrlichia chaffeensis].	25.40	437	258	13	47	452	232	631	1e-15	90.1
rs:WP_017613841	DNA topoisomerase I [Nocardiopsis salina].	26.48	355	211	11	42	379	277	598	1e-15	90.1
rs:WP_010996931	DNA topoisomerase I [Nostoc sp. PCC 7120].	25.00	372	231	9	41	395	249	589	1e-15	90.1
rs:WP_032976671	DNA topoisomerase I [Stenotrophomonas sp. RIT309].	30.13	302	164	12	66	350	254	525	1e-15	90.1
tr:A7A855_BIFAD	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EDN81920.1};	33.70	181	110	2	275	451	11	185	1e-15	86.7
rs:WP_046228045	DNA topoisomerase I [Paenibacillus dauci].	22.84	429	275	12	47	457	224	614	1e-15	90.1
rs:WP_016926149	DNA topoisomerase I [Rickettsia conorii].	25.30	415	243	16	65	449	250	627	1e-15	90.1
rs:WP_025879065	DNA topoisomerase I [Stenotrophomonas maltophilia].	30.13	302	164	12	66	350	254	525	1e-15	90.1
rs:WP_033832335	DNA topoisomerase I [Stenotrophomonas maltophilia].	30.13	302	164	12	66	350	254	525	1e-15	90.1
rs:WP_018029792	DNA topoisomerase I [Streptococcus ferus].	24.12	452	280	13	19	452	213	619	1e-15	90.1
tr:R9KZ71_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.82	424	267	12	48	454	233	617	1e-15	90.1
rs:WP_017443149	DNA topoisomerase I [Candidatus Rickettsia gravesii].	25.24	420	237	17	65	449	250	627	1e-15	90.1
rs:WP_037224279	DNA topoisomerase I [Richelia intracellularis].	25.13	378	235	11	41	401	255	601	1e-15	90.1
rs:WP_026515380	DNA topoisomerase I [Butyrivibrio sp. LB2008].	24.09	440	274	14	34	454	208	606	1e-15	90.1
tr:A0A0E2RVE6_STRTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.45	409	238	14	65	452	268	626	1e-15	90.1
tr:F6Z6P9_MACMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.00	436	255	14	41	450	299	688	1e-15	90.1
rs:WP_032823520	DNA topoisomerase I [Haemophilus influenzae].	26.12	379	231	14	77	446	290	628	1e-15	90.1
rs:WP_011681086	DNA topoisomerase I [Streptococcus thermophilus].	24.45	409	238	14	65	452	270	628	1e-15	90.1
rs:XP_011011407	PREDICTED: DNA topoisomerase 3-alpha-like isoform X2 [Populus euphratica].	23.24	469	285	14	18	451	236	664	1e-15	90.1
tr:J5L2K4_PASMD	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJS90469.1};	40.16	122	73	0	293	414	1	122	1e-15	84.3
rs:WP_044330152	DNA topoisomerase I [Haemophilus influenzae].	25.86	379	232	14	77	446	290	628	1e-15	90.1
tr:A0A0E2Q2V1_STRTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.45	409	238	14	65	452	270	628	1e-15	90.1
rs:WP_028089487	DNA topoisomerase I [Dolichospermum circinale].	24.93	369	235	10	41	395	249	589	1e-15	90.1
rs:WP_014518289	DNA topoisomerase I [Chlamydia pneumoniae].	26.70	412	237	17	60	449	254	622	1e-15	90.1
rs:XP_006688044	hypothetical protein CANTEDRAFT_108430 [Candida tenuis ATCC 10573].	26.51	347	199	12	53	379	270	580	1e-15	89.7
tr:X5JYV5_9NOST	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.13	378	235	11	41	401	226	572	1e-15	90.1
rs:WP_042594644	DNA topoisomerase I [Haemophilus influenzae].	26.12	379	231	14	77	446	290	628	1e-15	90.1
rs:XP_001568961	putative DNA topoisomerase III [Leishmania braziliensis MHOM/BR/75/M2904].	26.85	365	216	11	31	379	238	567	1e-15	90.1
tr:R9CB07_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOR24346.1};	27.68	271	151	8	170	434	23	254	1e-15	88.2
rs:WP_027853634	DNA topoisomerase I [Marinobacterium litorale].	25.77	423	260	16	43	452	261	642	1e-15	90.1
rs:WP_036280765	DNA topoisomerase I [Methylocystis sp. ATCC 49242].	27.15	431	237	18	60	452	243	634	1e-15	90.1
rs:WP_036432809	DNA topoisomerase I [Mycoplasma hominis].	24.40	377	213	13	92	450	271	593	1e-15	89.7
rs:WP_019805740	DNA topoisomerase I [Streptococcus mutans].	23.76	442	274	14	29	452	223	619	1e-15	89.7
rs:WP_046135880	DNA topoisomerase I [Devosia limi].	24.94	437	252	15	50	452	233	627	1e-15	90.1
rs:WP_022114217	DNA topoisomerase [Clostridium sp. CAG:245].	22.91	419	279	10	47	454	86	471	1e-15	89.7
tr:A0A0C7E5F3_XANCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.91	377	209	16	66	416	254	597	1e-15	90.1
rs:WP_014076565	DNA topoisomerase I [Sphingobium sp. SYK-6].	26.12	448	256	17	40	452	219	626	1e-15	90.1
rs:WP_014608256	DNA topoisomerase I [Streptococcus thermophilus].	24.45	409	238	14	65	452	270	628	1e-15	89.7
rs:WP_044565945	DNA topoisomerase I [Anaerococcus sp. 9402080].	24.87	398	227	15	77	452	254	601	1e-15	89.7
rs:WP_012677973	DNA topoisomerase I [Streptococcus equi].	23.56	416	242	13	61	452	262	625	1e-15	89.7
rs:WP_027216148	DNA topoisomerase I [Butyrivibrio fibrisolvens].	24.23	421	264	11	50	454	232	613	1e-15	89.7
rs:WP_024785252	DNA topoisomerase I [Streptococcus mutans].	23.76	442	274	14	29	452	223	619	1e-15	89.7
rs:WP_007317029	DNA topoisomerase I [Gordonia effusa].	26.69	341	200	10	35	354	255	566	1e-15	90.1
rs:WP_034854032	DNA topoisomerase I [Ensifer sojae].	24.32	440	268	14	47	452	230	638	1e-15	90.1
rs:WP_003869178	DNA topoisomerase I [Thermoanaerobacter ethanolicus].	26.55	452	255	19	28	454	213	612	1e-15	89.7
rs:WP_012679592	DNA topoisomerase I [Streptococcus equi].	23.56	416	242	13	61	452	262	625	1e-15	89.7
rs:WP_044413633	DNA topoisomerase I [Thioalkalimicrobium microaerophilum].	28.57	308	170	10	33	334	215	478	1e-15	90.1
rs:WP_022756508	DNA topoisomerase I [Butyrivibrio fibrisolvens].	24.23	421	264	11	50	454	232	613	1e-15	89.7
rs:WP_019404447	DNA topoisomerase I [Chelatococcus sp. GW1].	27.38	420	233	17	68	452	252	634	1e-15	90.1
rs:WP_014727521	DNA topoisomerase I [Streptococcus thermophilus].	24.45	409	238	14	65	452	270	628	1e-15	89.7
rs:WP_045846408	DNA topoisomerase I [Aquitalea magnusonii].	23.95	476	262	14	50	459	234	675	1e-15	90.1
rs:WP_029103165	DNA topoisomerase I [Moraxella caprae].	25.52	431	259	18	38	452	249	633	1e-15	90.1
rs:WP_029152330	DNA topoisomerase I [Microbacterium gubbeenense].	28.21	319	184	9	45	354	267	549	1e-15	90.1
rs:WP_022514491	GTP-sensing transcriptional pleiotropic repressor CodY [Roseburia sp. CAG:182].	23.95	430	265	13	48	457	227	614	1e-15	89.7
rs:WP_027205784	DNA topoisomerase I [Butyrivibrio fibrisolvens].	24.23	421	264	11	50	454	232	613	1e-15	89.7
rs:WP_040572020	DNA topoisomerase I [Shewanella benthica].	26.29	350	211	11	53	388	267	583	1e-15	90.1
rs:WP_038289556	DNA topoisomerase I [Zooshikella ganghwensis].	26.61	436	266	16	19	446	242	631	1e-15	90.1
tr:A0A091G822_9AVES	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.97	438	261	15	25	434	224	617	1e-15	90.1
rs:WP_032108967	DNA topoisomerase I [Haemophilus sp. FF7].	27.56	381	223	17	77	446	290	628	1e-15	90.1
rs:WP_046466609	DNA topoisomerase I [Staphylococcus pasteuri].	23.29	425	265	15	47	452	224	606	1e-15	89.7
rs:WP_014159758	DNA topoisomerase I [Pseudoxanthomonas spadix].	31.48	305	155	15	66	350	254	524	1e-15	90.1
rs:WP_021398006	DNA topoisomerase I [Peptoclostridium difficile].	21.56	436	283	10	36	454	215	608	1e-15	89.7
rs:WP_021377880	DNA topoisomerase I [Peptoclostridium difficile].	21.79	436	282	10	36	454	215	608	1e-15	89.7
tr:Q6WWY9_PSEAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.55	411	241	14	74	459	252	622	1e-15	89.7
rs:WP_002950606	DNA topoisomerase I [Streptococcus thermophilus].	24.45	409	238	14	65	452	270	628	1e-15	89.7
gp:LN847056_15	DNA topoisomerase 1 [Chlamydia pneumoniae]	26.70	412	237	17	60	449	254	622	1e-15	90.1
rs:WP_012739047	DNA topoisomerase I [[Eubacterium] eligens].	24.82	427	260	12	50	457	229	613	1e-15	89.7
rs:WP_006458716	DNA topoisomerase I [Synechococcus sp. PCC 7335].	23.64	423	265	14	40	445	237	618	1e-15	89.7
rs:WP_025478161	DNA topoisomerase I [Enterococcus faecium].	25.00	404	236	13	77	457	255	614	1e-15	89.7
tr:A0A0F3R5G2_RICAM	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJV99973.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KJV99973.1};	25.24	420	237	17	65	449	51	428	1e-15	89.7
rs:WP_022740904	DNA topoisomerase I [Lachnospiraceae bacterium COE1].	23.82	424	267	12	48	454	227	611	1e-15	89.7
rs:WP_027974779	DNA topoisomerase I [Streptococcus porci].	25.28	447	250	19	34	452	229	619	1e-15	89.7
rs:WP_011328029	topoisomerase I [Pseudoalteromonas haloplanktis].	26.47	374	227	12	36	395	251	590	1e-15	90.1
rs:WP_022246783	DNA topoisomerase [Clostridium sp. CAG:306].	25.99	431	253	16	43	454	239	622	1e-15	89.7
rs:WP_014767919	DNA topoisomerase I [Desulfurococcus fermentans].	25.06	391	244	14	47	424	258	612	1e-15	89.7
tr:A0A0F0M0P0_9MICO	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:KJL42368.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KJL42368.1};	27.54	345	200	11	46	377	276	583	1e-15	90.1
tr:A5UT75_ROSS1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.19	492	250	15	47	452	230	684	1e-15	89.7
rs:WP_045800259	DNA topoisomerase I [Candidatus Rickettsia amblyommii].	25.24	420	237	17	65	449	250	627	1e-15	89.7
rs:WP_014392084	DNA topoisomerase I [Candidatus Rickettsia amblyommii].	25.24	420	237	17	65	449	250	627	1e-15	89.7
tr:E9NQ03_LEIDO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.92	355	220	8	37	379	244	567	1e-15	90.1
rs:WP_034527452	DNA topoisomerase I [Lactobacillus oryzae].	25.86	406	238	16	65	452	255	615	1e-15	89.7
rs:WP_045246069	DNA topoisomerase I [Microbacterium ginsengisoli].	27.54	345	200	11	46	377	253	560	1e-15	90.1
tr:A0A094RJF9_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.94	311	161	12	77	370	287	554	1e-15	90.1
rs:WP_037057711	DNA topoisomerase I, partial [Pseudonocardia asaccharolytica].	28.06	335	195	9	35	354	281	584	1e-15	90.1
rs:WP_015060259	MULTISPECIES: DNA topoisomerase I [environmental samples].	24.10	444	276	16	22	459	216	604	1e-15	89.7
rs:WP_002809370	DNA topoisomerase I [Xanthomonas fragariae].	28.91	377	209	16	66	416	254	597	1e-15	89.7
rs:XP_009564658	PREDICTED: DNA topoisomerase 3-beta-1 [Cuculus canorus].	23.97	438	261	15	25	434	247	640	1e-15	90.1
rs:WP_009425403	DNA topoisomerase I [Neisseria sp. oral taxon 020].	26.05	430	256	14	43	452	228	615	1e-15	89.7
rs:WP_026487707	DNA topoisomerase I [Butyrivibrio sp. XBB1001].	25.00	424	261	14	48	454	223	606	1e-15	89.7
rs:WP_032818902	topoisomerase I, partial [Oenococcus oeni].	27.39	241	147	9	230	454	1	229	1e-15	87.0
rs:WP_012259747	MULTISPECIES: DNA topoisomerase I [Chloroflexus].	26.48	423	256	13	47	446	231	621	1e-15	89.7
rs:WP_010963054	DNA topoisomerase I [Wolbachia endosymbiont of Drosophila melanogaster].	25.34	442	252	15	47	452	231	630	1e-15	89.7
rs:WP_008960772	DNA topoisomerase I [Bradyrhizobium sp. STM 3809].	25.35	426	255	12	60	454	194	587	1e-15	90.1
rs:WP_036692472	DNA topoisomerase I [Paenibacillus sp. FSL R7-269].	23.72	430	264	14	50	457	227	614	1e-15	89.7
rs:WP_027323376	DNA topoisomerase I [Bacillus sp. URHB0009].	24.94	433	251	16	46	452	224	608	1e-15	89.7
rs:WP_004812098	DNA topoisomerase I [Anaerococcus hydrogenalis].	24.11	394	236	13	77	452	254	602	1e-15	89.7
tr:J6ZEN4_ENTFC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	404	236	13	77	457	273	632	1e-15	89.7
rs:WP_007647546	topoisomerase I [Shewanella sp. HN-41].	25.47	424	262	15	35	446	250	631	1e-15	90.1
rs:WP_003607894	DNA topoisomerase I [Weissella confusa].	24.68	466	273	18	18	452	212	630	1e-15	89.7
rs:WP_006453157	DNA topoisomerase I [Xanthomonas gardneri].	28.91	377	209	15	66	416	254	597	1e-15	89.7
rs:WP_017288219	hypothetical protein [Leptolyngbya boryana].	28.18	330	195	11	41	358	252	551	1e-15	90.1
rs:WP_014273369	DNA topoisomerase I [Rickettsia slovaca].	25.30	415	243	16	65	449	250	627	1e-15	89.7
rs:WP_004396182	MULTISPECIES: DNA topoisomerase I [Thermoanaerobacter].	26.11	452	257	18	28	454	213	612	1e-15	89.7
rs:WP_007891355	DNA topoisomerase I [Streptococcus pseudoporcinus].	23.37	415	244	15	61	452	261	624	1e-15	89.7
rs:WP_002360765	hypothetical protein, partial [Enterococcus faecium].	37.31	134	75	3	232	365	3	127	1e-15	85.9
rs:WP_016264249	DNA topoisomerase I [Pseudomonas aeruginosa].	25.37	410	243	13	74	459	260	630	1e-15	89.7
rs:WP_042214914	DNA topoisomerase I [Paenibacillus borealis].	23.78	429	265	13	50	457	227	614	1e-15	89.7
tr:Q3EKS1_BACTI	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EAO51911.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EAO51911.1};	29.95	187	113	4	274	448	4	184	1e-15	86.3
rs:WP_040396702	DNA topoisomerase I [Anaerococcus senegalensis].	22.78	461	285	14	18	452	187	602	1e-15	89.7
tr:M0WQP5_HORVD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.95	447	257	17	39	452	266	671	1e-15	89.7
tr:A0A085MJL8_9BILA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.46	466	248	21	39	451	264	678	1e-15	90.1
rs:WP_009505253	DNA topoisomerase I [Citreicella sp. 357].	26.71	468	233	18	50	454	244	664	1e-15	89.7
rs:WP_044170579	DNA topoisomerase I [Ehrlichia chaffeensis].	25.40	437	258	13	47	452	232	631	1e-15	89.7
tr:L9LCG8_TUPCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.54	446	249	16	41	453	348	734	1e-15	89.7
rs:WP_020002660	DNA topoisomerase I [Mycoplasma hominis].	24.40	377	213	13	92	450	271	593	1e-15	89.4
rs:WP_011256239	DNA topoisomerase I [Wolbachia endosymbiont of Brugia malayi].	24.60	443	254	15	47	452	231	630	1e-15	89.7
rs:WP_038199520	DNA topoisomerase I [Wolbachia pipientis].	25.34	442	252	15	47	452	231	630	1e-15	89.7
rs:WP_044069817	DNA topoisomerase I [Pseudomonas aeruginosa].	25.61	410	242	13	74	459	260	630	1e-15	89.7
rs:WP_012200735	DNA topoisomerase I [Lachnoclostridium phytofermentans].	23.65	427	264	12	48	454	227	611	1e-15	89.7
rs:XP_008807898	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Phoenix dactylifera].	25.06	443	265	15	39	452	270	674	1e-15	89.7
rs:WP_026515776	DNA topoisomerase I [Butyrivibrio sp. MC2021].	23.74	438	278	13	34	454	208	606	1e-15	89.7
rs:WP_028083163	DNA topoisomerase I [Dolichospermum circinale].	24.93	369	235	10	41	395	249	589	1e-15	89.7
rs:WP_025280338	DNA topoisomerase I [Ectothiorhodospira haloalkaliphila].	28.52	298	182	9	61	350	248	522	1e-15	89.7
rs:WP_039217791	DNA topoisomerase I [Clostridium novyi].	25.00	416	234	18	66	454	244	608	1e-15	89.7
rs:WP_040099963	DNA topoisomerase I, partial [Geoalkalibacter ferrihydriticus].	25.55	411	242	16	66	454	254	622	1e-15	89.7
rs:XP_008807899	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Phoenix dactylifera].	25.11	442	266	14	39	452	270	674	1e-15	89.7
rs:WP_047966623	DNA topoisomerase I [Vogesella sp. EB].	25.62	445	263	14	28	452	218	614	1e-15	89.7
rs:WP_028646671	DNA topoisomerase I [Nocardiopsis sp. CNT312].	26.42	352	215	10	40	377	274	595	1e-15	89.7
rs:WP_026666845	DNA topoisomerase I [Butyrivibrio sp. AE2005].	24.10	444	274	13	28	454	209	606	1e-15	89.7
rs:WP_042595233	DNA topoisomerase I [Xanthomonas campestris].	29.21	380	204	16	66	416	254	597	1e-15	89.7
rs:WP_046826724	DNA topoisomerase I [Afipia massiliensis].	25.73	443	263	15	45	454	228	637	1e-15	89.7
rs:WP_021475572	DNA topoisomerase I [Pseudogulbenkiania ferrooxidans].	26.17	428	246	13	49	452	233	614	1e-15	89.7
rs:WP_017298517	hypothetical protein [Nodosilinea nodulosa].	26.82	399	244	13	24	403	228	597	1e-15	89.7
rs:WP_017578818	DNA topoisomerase I [Nocardiopsis valliformis].	26.61	357	220	10	36	379	271	598	1e-15	89.7
tr:A9EHJ0_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.29	350	211	11	53	388	283	599	1e-15	89.7
tr:D7CT23_TRURR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.01	332	195	10	26	344	248	548	1e-15	89.7
rs:WP_036438960	DNA topoisomerase I [Mycoplasma hominis].	24.40	377	213	13	92	450	271	593	1e-15	89.4
rs:WP_032828011	DNA topoisomerase I [Haemophilus haemolyticus].	25.86	379	232	14	77	446	290	628	1e-15	89.7
rs:WP_046949842	DNA topoisomerase I [Haemophilus haemolyticus].	25.86	379	232	14	77	446	290	628	1e-15	89.7
rs:WP_033543929	DNA topoisomerase I [Planococcus sp. CAU13].	25.47	424	252	16	50	452	227	607	1e-15	89.7
tr:A4TWS2_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.67	435	242	16	60	454	243	640	1e-15	89.7
rs:WP_020046071	DNA topoisomerase I [actinobacterium SCGC AAA027-M14].	28.57	329	188	11	41	354	256	552	1e-15	89.7
rs:WP_042520547	DNA topoisomerase I [Lactobacillus brevis].	25.06	439	260	15	41	457	234	625	1e-15	89.7
rs:WP_026512315	DNA topoisomerase I [Butyrivibrio sp. NC2007].	23.88	423	267	13	48	454	223	606	1e-15	89.7
rs:WP_022930930	DNA topoisomerase I [Treponema bryantii].	23.14	458	265	15	43	449	228	649	1e-15	89.7
rs:WP_004834834	DNA topoisomerase I [Anaerococcus prevotii].	22.94	462	282	15	18	452	187	601	1e-15	89.7
rs:WP_032820195	DNA topoisomerase I, partial [Oenococcus oeni].	24.56	399	242	11	70	452	257	612	1e-15	89.4
rs:WP_022672346	DNA topoisomerase I [Sphingopyxis baekryungensis].	26.86	484	285	19	1	452	171	617	1e-15	89.7
rs:WP_014085710	DNA topoisomerase I [Pseudogulbenkiania sp. NH8B].	25.92	436	267	14	31	452	221	614	1e-15	89.7
rs:WP_036751414	DNA topoisomerase I [Paracoccus versutus].	25.64	429	258	14	51	454	233	625	1e-15	89.7
rs:WP_025095361	DNA topoisomerase I [Acinetobacter soli].	25.59	426	262	18	40	452	269	652	1e-15	89.7
rs:WP_040084713	DNA topoisomerase I [Corynebacterium humireducens].	25.29	340	213	8	30	356	252	563	1e-15	89.7
rs:WP_025730271	DNA topoisomerase I [Atopobacter phocae].	22.59	425	271	12	45	452	226	609	1e-15	89.4
rs:WP_029175409	DNA topoisomerase [Streptococcus suis].	26.97	330	207	10	60	385	264	563	1e-15	89.4
rs:WP_019517463	DNA topoisomerase I [Sphingomonas sp. Mn802worker].	26.99	415	243	14	60	452	241	617	1e-15	89.7
rs:WP_026660394	DNA topoisomerase I [Butyrivibrio sp. AC2005].	23.65	427	263	13	48	454	232	615	1e-15	89.4
rs:NP_639100	DNA topoisomerase I [Xanthomonas campestris pv. campestris str. ATCC 33913].	29.21	380	204	16	66	416	254	597	1e-15	89.7
rs:WP_028561444	DNA topoisomerase I [Paenibacillus pinihumi].	24.83	447	270	15	35	457	211	615	1e-15	89.4
tr:A0A091IK67_CALAN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.26	437	261	15	25	434	224	617	1e-15	89.7
rs:WP_035167132	DNA topoisomerase I [Lactobacillus curieae].	24.71	437	259	17	43	457	238	626	1e-15	89.4
rs:WP_042744536	DNA topoisomerase I, partial [Oenococcus oeni].	24.56	399	242	11	70	452	254	609	1e-15	89.4
rs:WP_002472398	MULTISPECIES: DNA topoisomerase I [Staphylococcus].	23.86	394	240	12	77	452	254	605	1e-15	89.4
rs:WP_022171308	GTP-sensing transcriptional pleiotropic repressor CodY [Blautia sp. CAG:52].	24.36	427	269	11	47	457	226	614	1e-15	89.4
rs:WP_005314340	DNA topoisomerase I [Streptomyces pristinaespiralis].	26.01	373	216	14	8	354	219	557	1e-15	89.7
rs:WP_045298032	DNA topoisomerase I [Microbacterium trichothecenolyticum].	29.47	319	168	13	51	354	273	549	1e-15	89.7
rs:WP_002817146	DNA topoisomerase I [Oenococcus oeni].	24.56	399	242	11	70	452	254	609	1e-15	89.4
rs:WP_042664349	hypothetical protein [Aigarchaeota archaeon SCGC AAA471-F17].	26.46	325	195	9	60	379	253	538	1e-15	89.4
rs:WP_019318257	DNA topoisomerase I [Streptococcus mutans].	23.45	452	283	14	19	452	213	619	1e-15	89.4
rs:WP_007257738	DNA topoisomerase I [Natronolimnobius innermongolicus].	22.94	401	269	10	60	454	267	633	1e-15	89.7
rs:WP_005729974	hypothetical protein [Lactobacillus crispatus].	23.62	453	268	14	59	445	278	718	1e-15	89.7
rs:WP_039518565	DNA topoisomerase I [Xanthomonas arboricola].	28.53	382	206	15	66	413	254	602	1e-15	89.7
rs:WP_027424619	DNA topoisomerase I [Lachnospiraceae bacterium AC3007].	26.52	411	239	16	61	452	244	610	1e-15	89.4
rs:WP_038298915	DNA topoisomerase I, partial [actinobacterium acMicro-4].	28.94	311	161	12	77	370	287	554	1e-15	89.7
rs:WP_002287487	DNA topoisomerase I [Streptococcus mutans].	23.76	442	274	14	29	452	223	619	1e-15	89.4
rs:WP_024870611	DNA topoisomerase I [Tolumonas sp. BRL6-1].	26.38	436	254	17	38	452	246	635	1e-15	89.7
rs:WP_024955483	DNA topoisomerase I [Sulfurospirillum arcachonense].	23.83	449	245	16	60	450	237	646	1e-15	89.4
rs:WP_040941924	DNA topoisomerase I [Xanthomonas campestris].	28.91	377	209	16	66	416	254	597	1e-15	89.7
rs:WP_034984787	DNA topoisomerase III, partial [Bifidobacterium adolescentis].	32.62	187	116	2	269	451	18	198	1e-15	86.3
rs:WP_036872957	DNA topoisomerase I [Prevotella buccalis].	25.49	357	230	11	77	411	252	594	1e-15	89.7
tr:U3ICG2_ANAPL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.97	438	261	15	25	434	87	480	1e-15	89.4
rs:WP_021583868	DNA topoisomerase, partial [Prevotella pleuritidis].	29.85	201	123	5	74	271	276	461	1e-15	89.0
rs:WP_041080448	DNA topoisomerase I [Staphylococcus saprophyticus].	22.45	432	273	13	40	452	217	605	1e-15	89.4
rs:WP_012707655	DNA topoisomerase I [Sinorhizobium fredii].	25.51	439	264	14	47	452	230	638	1e-15	89.7
rs:XP_008301799	PREDICTED: DNA topoisomerase 3-beta-1 [Stegastes partitus].	23.81	441	256	15	40	453	263	650	1e-15	89.7
rs:WP_041948020	DNA topoisomerase I, partial [Truepera radiovictrix].	28.01	332	195	10	26	344	248	548	1e-15	89.7
rs:WP_039695713	DNA topoisomerase [Streptococcus gallolyticus].	27.83	345	191	13	74	401	278	581	1e-15	89.4
rs:WP_019510772	MULTISPECIES: DNA topoisomerase I [Mycobacterium].	26.79	392	233	13	41	410	268	627	1e-15	89.7
tr:F9QAQ0_9PAST	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.33	375	239	12	77	446	214	552	1e-15	89.7
rs:WP_024783479	DNA topoisomerase I [Streptococcus mutans].	23.76	442	274	14	29	452	223	619	1e-15	89.4
tr:F9GUB0_HAEHA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.86	379	232	14	77	446	296	634	1e-15	89.7
rs:WP_020267267	hypothetical protein [Aigarchaeota archaeon JGI 0000001-H6].	26.46	325	195	9	60	379	253	538	1e-15	89.4
rs:WP_028527339	DNA topoisomerase I [Ruminococcus gauvreauii].	25.12	414	255	12	61	457	240	615	1e-15	89.4
rs:WP_002265839	DNA topoisomerase I [Streptococcus mutans].	23.76	442	274	14	29	452	223	619	1e-15	89.4
rs:WP_031631577	DNA topoisomerase I [Pseudomonas aeruginosa].	25.61	410	242	13	74	459	260	630	1e-15	89.4
rs:WP_024078549	DNA topoisomerase I [Magnetospirillum gryphiswaldense].	26.67	435	242	16	60	454	243	640	1e-15	89.7
gp:CP006256_3668	Topoisomerase IA [Pseudomonas syringae pv. syringae HS191]	39.39	132	77	2	31	159	321	452	1e-15	89.0
rs:WP_017486547	DNA topoisomerase I [Methylobacterium sp. MB200].	26.62	447	243	15	43	452	236	634	1e-15	89.7
rs:WP_026835620	DNA topoisomerase I [Eubacterium xylanophilum].	22.22	423	274	12	48	454	226	609	1e-15	89.4
rs:WP_044064261	DNA topoisomerase I, partial [Prevotella saccharolytica].	26.55	275	176	8	30	294	180	438	1e-15	88.6
rs:XP_006581777	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Glycine max].	24.21	442	270	16	39	451	261	666	1e-15	89.7
rs:WP_032811318	DNA topoisomerase I, partial [Oenococcus oeni].	24.56	399	242	11	70	452	254	609	1e-15	89.4
tr:A7ZFR7_CAMC1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.90	394	220	16	77	450	254	599	1e-15	89.4
rs:WP_044270718	DNA topoisomerase I [Candidatus Bacteroides timonensis].	25.59	383	235	13	21	387	220	568	1e-15	89.4
rs:XP_010649355	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Vitis vinifera].	25.06	443	259	17	41	452	262	662	1e-15	89.7
rs:WP_028505977	DNA topoisomerase I [Ruminococcus sp. FC2018].	24.29	424	264	13	48	452	226	611	1e-15	89.4
rs:WP_032806012	DNA topoisomerase I [Oenococcus oeni].	24.56	399	242	11	70	452	254	609	1e-15	89.4
rs:WP_028653086	DNA topoisomerase I [Nocardioides halotolerans].	29.73	333	185	15	39	356	252	550	1e-15	89.7
rs:WP_009294935	DNA topoisomerase I [Campylobacter sp. 10_1_50].	26.90	394	220	16	77	450	254	599	1e-15	89.4
rs:WP_002267968	DNA topoisomerase I [Streptococcus mutans].	23.98	442	273	14	29	452	223	619	1e-15	89.4
rs:WP_026466076	DNA topoisomerase I [Aerococcus urinaeequi].	24.71	437	252	17	41	452	219	603	1e-15	89.4
rs:WP_032823308	DNA topoisomerase I [Oenococcus oeni].	24.56	399	242	11	70	452	254	609	1e-15	89.4
rs:WP_040197506	DNA topoisomerase I [Candidatus Soleaferrea massiliensis].	25.06	435	261	13	41	452	219	611	1e-15	89.4
rs:WP_011227156	DNA topoisomerase I [Streptococcus thermophilus].	24.45	409	238	14	65	452	270	628	1e-15	89.4
rs:WP_034021225	DNA topoisomerase I [Pseudomonas aeruginosa].	25.61	410	242	13	74	459	260	630	1e-15	89.4
rs:WP_004932739	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	25.59	426	262	18	40	452	269	652	1e-15	89.7
rs:WP_042166570	DNA topoisomerase I [Pseudomonas aeruginosa].	24.57	411	245	13	74	459	260	630	1e-15	89.4
tr:A0A061I877_CRIGR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.58	441	255	17	40	453	194	579	1e-15	89.4
rs:WP_021091637	DNA topoisomerase I [Campylobacter concisus].	26.90	394	220	16	77	450	254	599	1e-15	89.4
rs:WP_003134111	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	25.06	411	243	13	74	459	260	630	1e-15	89.4
rs:WP_002880888	DNA topoisomerase I [Mycoplasma alkalescens].	25.33	379	205	14	92	449	271	592	1e-15	89.4
rs:WP_011580693	DNA topoisomerase I [Chelativorans sp. BNC1].	24.04	441	265	14	47	452	230	635	1e-15	89.7
rs:WP_002264284	DNA topoisomerase I [Streptococcus mutans].	23.76	442	274	14	29	452	223	619	2e-15	89.4
tr:E8TUJ8_ALIDB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	36.11	108	69	0	61	168	267	374	2e-15	88.2
rs:XP_008500955	PREDICTED: DNA topoisomerase 3-beta-1 [Calypte anna].	24.26	437	261	15	25	434	247	640	2e-15	89.7
rs:WP_008230948	DNA topoisomerase I [Roseobacter sp. CCS2].	26.34	429	248	17	48	452	242	626	2e-15	89.7
rs:WP_000246605	DNA topoisomerase I [Streptococcus agalactiae].	22.43	437	276	13	34	452	229	620	2e-15	89.4
rs:WP_032818446	DNA topoisomerase I [Oenococcus oeni].	24.56	399	242	11	70	452	254	609	2e-15	89.4
rs:XP_011211844	PREDICTED: DNA topoisomerase 3-beta [Bactrocera dorsalis].	24.72	356	227	12	37	385	256	577	2e-15	89.7
rs:WP_042599491	DNA topoisomerase I [Haemophilus influenzae].	25.86	379	232	14	77	446	290	628	2e-15	89.7
rs:WP_039284392	DNA topoisomerase I [Novosphingobium malaysiense].	25.71	490	284	17	1	452	171	618	2e-15	89.7
rs:WP_015153445	DNA topoisomerase I [Chroococcidiopsis thermalis].	25.21	357	226	9	41	387	253	578	2e-15	89.7
rs:WP_041173544	DNA topoisomerase I [Clostridium botulinum].	24.36	431	236	15	74	449	252	647	2e-15	89.4
rs:WP_041266580	DNA topoisomerase I, partial [Gemmatimonas aurantiaca].	26.17	447	254	18	47	458	308	713	2e-15	89.4
rs:WP_028392863	DNA topoisomerase I [Bacillus sp. FJAT-14515].	23.08	429	267	15	50	457	227	613	2e-15	89.4
rs:WP_013313691	DNA topoisomerase I [Spirochaeta thermophila].	25.29	427	256	16	47	454	235	617	2e-15	89.4
rs:WP_046830945	DNA topoisomerase I [Xanthomonas axonopodis].	27.21	430	258	18	38	459	215	597	2e-15	89.4
rs:WP_016508253	DNA topoisomerase I [Exiguobacterium sp. S17].	24.94	429	267	12	45	454	222	614	2e-15	89.4
tr:F9EQV8_FUSNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.60	312	182	8	80	377	4	282	2e-15	87.8
tr:W7TAY5_9STRA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.54	345	203	11	17	351	227	534	2e-15	89.4
rs:WP_024859995	DNA topoisomerase I [Ruminococcus flavefaciens].	24.25	433	266	13	41	452	219	610	2e-15	89.4
rs:XP_006875592	PREDICTED: DNA topoisomerase 3-alpha [Chrysochloris asiatica].	24.27	445	268	15	40	455	264	668	2e-15	89.7
rs:WP_033973543	DNA topoisomerase I [Pseudomonas aeruginosa].	25.37	410	243	13	74	459	260	630	2e-15	89.4
rs:WP_014365975	MULTISPECIES: DNA topoisomerase I [spotted fever group].	24.49	445	258	18	41	449	225	627	2e-15	89.4
rs:WP_002351490	hypothetical protein [Streptococcus mutans].	27.00	363	216	14	49	399	252	577	2e-15	89.0
rs:WP_011927356	DNA topoisomerase I [Bradyrhizobium sp. ORS 278].	25.12	426	256	12	60	454	243	636	2e-15	89.4
rs:WP_015904582	DNA topoisomerase I [Desulfobacterium autotrophicum].	23.72	430	260	15	43	449	221	605	2e-15	89.4
rs:WP_008930828	DNA topoisomerase I [Ectothiorhodospira sp. PHS-1].	27.42	310	191	9	50	350	238	522	2e-15	89.4
rs:WP_002780028	DNA topoisomerase 1 [Microcystis aeruginosa].	24.60	378	237	11	41	401	249	595	2e-15	89.4
rs:WP_020916758	DNA topoisomerase III [Streptococcus lutetiensis].	27.15	372	212	14	48	401	251	581	2e-15	89.0
tr:B1KWM7_CLOBM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.36	431	236	15	74	449	256	651	2e-15	89.4
rs:WP_029573099	DNA topoisomerase I, partial [Pseudomonas syringae].	28.80	316	184	12	47	356	259	539	2e-15	89.0
tr:B9KIC6_ANAMF	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.07	445	252	17	43	452	229	631	2e-15	89.4
rs:WP_042594037	DNA topoisomerase I [Haemophilus influenzae].	25.86	379	232	14	77	446	290	628	2e-15	89.4
rs:WP_020743415	DNA topoisomerase I subunit omega [Alteromonas macleodii].	26.20	416	253	16	43	446	257	630	2e-15	89.4
rs:WP_024611339	DNA topoisomerase I [Pseudoalteromonas haloplanktis].	26.67	360	219	11	36	384	251	576	2e-15	89.4
tr:R0L3G6_ANAPL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.97	438	261	15	25	434	231	624	2e-15	89.4
rs:WP_012800727	topoisomerase I [Kangiella koreensis].	26.38	345	208	12	51	384	270	579	2e-15	89.4
rs:WP_038685971	DNA topoisomerase I [Stenotrophomonas rhizophila].	30.13	302	164	11	66	350	254	525	2e-15	89.4
rs:WP_010264176	DNA topoisomerase I [Anaplasma marginale].	26.07	445	252	17	43	452	228	630	2e-15	89.4
rs:WP_023386700	DNA topoisomerase I [Anaplasma marginale].	26.07	445	252	17	43	452	228	630	2e-15	89.4
rs:WP_013266347	DNA topoisomerase III [Acidilobus saccharovorans].	26.90	368	215	13	74	425	285	614	2e-15	89.4
rs:WP_044828820	DNA topoisomerase I [Thalassospira sp. HJ].	24.71	425	247	15	65	454	248	634	2e-15	89.4
rs:WP_007341842	MULTISPECIES: DNA topoisomerase I [Neisseria].	26.40	428	257	12	43	452	228	615	2e-15	89.4
rs:XP_012269908	PREDICTED: DNA topoisomerase 3-beta-1 [Athalia rosae].	25.20	373	231	11	24	385	245	580	2e-15	89.4
rs:WP_023273414	DNA topoisomerase I [Acinetobacter nectaris].	26.50	351	210	12	18	356	239	553	2e-15	89.4
tr:G3W4B0_SARHA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.91	406	246	14	18	397	177	541	2e-15	89.4
rs:WP_041350251	DNA topoisomerase I [Clostridium botulinum].	24.13	431	237	15	74	449	252	647	2e-15	89.4
rs:WP_005248729	DNA topoisomerase I [Acinetobacter sp. CIP 51.11].	24.10	444	276	16	22	459	216	604	2e-15	89.4
rs:WP_003464928	DNA topoisomerase III [Clostridium perfringens].	26.85	365	226	17	98	452	306	639	2e-15	89.4
rs:XP_005855616	DNA topoisomerase III [Nannochloropsis gaditana CCMP526].	27.86	341	199	11	17	347	222	525	2e-15	89.4
rs:WP_009230497	DNA topoisomerase I [Prevotella sp. oral taxon 317].	27.36	329	201	10	30	351	207	504	2e-15	89.4
rs:WP_044860249	DNA topoisomerase III, partial [Enterobacter cloacae].	44.19	86	48	0	36	121	249	334	2e-15	87.0
rs:WP_011137815	DNA topoisomerase I [Chromobacterium violaceum].	25.93	428	247	13	49	452	233	614	2e-15	89.4
rs:WP_002822536	DNA topoisomerase I [Oenococcus oeni].	24.56	399	242	11	70	452	254	609	2e-15	89.4
rs:WP_020073187	DNA topoisomerase I [[Clostridium] sporosphaeroides].	25.84	445	254	19	36	452	214	610	2e-15	89.4
rs:XP_009869553	PREDICTED: DNA topoisomerase 3-alpha, partial [Apaloderma vittatum].	25.58	430	249	16	60	456	295	686	2e-15	89.4
rs:WP_003931741	DNA topoisomerase I [Mycobacterium vaccae].	26.28	392	235	13	41	410	277	636	2e-15	89.4
rs:WP_019231241	hypothetical protein [Rickettsiaceae bacterium Os18].	25.91	440	257	17	47	452	232	636	2e-15	89.4
rs:WP_037414251	DNA topoisomerase I [Sinorhizobium sp. CCBAU 05631].	25.11	438	267	13	47	452	230	638	2e-15	89.4
rs:WP_029889569	hypothetical protein, partial [Polycyclovorans algicola].	28.31	325	181	11	44	350	232	522	2e-15	89.4
rs:WP_007307655	DNA topoisomerase I [Crocosphaera watsonii].	24.77	436	259	13	25	436	216	606	2e-15	89.4
rs:XP_005021234	PREDICTED: DNA topoisomerase 3-beta-1 [Anas platyrhynchos].	23.97	438	261	15	25	434	247	640	2e-15	89.4
rs:WP_044860248	DNA topoisomerase III, partial [Enterobacter cloacae].	44.19	86	48	0	36	121	249	334	2e-15	87.0
rs:WP_042670629	DNA topoisomerase I [Streptococcus equi].	23.56	416	242	13	61	452	262	625	2e-15	89.4
rs:WP_012854854	DNA topoisomerase I [Thermomonospora curvata].	26.42	352	215	12	42	379	277	598	2e-15	89.4
rs:WP_033801726	DNA topoisomerase III, partial [Escherichia coli].	31.25	176	103	4	280	443	1	170	2e-15	85.5
rs:WP_002278553	DNA topoisomerase I [Streptococcus mutans].	23.76	442	274	14	29	452	223	619	2e-15	89.4
rs:WP_041409512	DNA topoisomerase I [Sinorhizobium fredii].	25.11	438	267	13	47	452	230	638	2e-15	89.4
rs:WP_022204968	DNA topoisomerase [Eubacterium sp. CAG:248].	25.30	419	246	13	61	457	240	613	2e-15	89.4
rs:WP_044503664	DNA topoisomerase I [Megasphaera sp. NP3].	24.26	470	278	16	18	452	239	665	2e-15	89.4
rs:WP_034325702	DNA topoisomerase I [Helicobacter sp. MIT 03-1616].	25.87	433	258	15	41	454	216	604	2e-15	89.4
rs:WP_005987997	DNA topoisomerase I [Xanthomonas vesicatoria].	28.80	382	205	16	66	413	254	602	2e-15	89.4
rs:WP_014939949	DNA topoisomerase I [Lactobacillus buchneri].	25.48	420	242	18	55	452	255	625	2e-15	89.4
rs:WP_048126946	DNA topoisomerase [Methanosarcina lacustris].	25.05	455	257	19	34	454	238	642	2e-15	89.4
rs:WP_034343711	DNA topoisomerase I [Helicobacter typhlonius].	25.87	433	258	15	41	454	216	604	2e-15	89.4
rs:WP_044657087	DNA topoisomerase I, partial [Bacteroides acidifaciens].	29.55	247	159	6	182	427	7	239	2e-15	86.7
rs:WP_042687066	hypothetical protein [Candidatus Glomeribacter gigasporarum].	39.85	133	78	2	254	384	3	135	2e-15	84.3
rs:WP_039715725	DNA topoisomerase I [Scytonema millei].	25.21	357	226	9	41	387	248	573	2e-15	89.4
rs:WP_022096555	DNA topoisomerase [Streptococcus thermophilus CAG:236].	24.45	409	238	14	65	452	270	628	2e-15	89.4
rs:WP_039446947	DNA topoisomerase I [Xanthomonas vasicola].	28.76	379	209	16	66	413	254	602	2e-15	89.4
rs:WP_034063959	DNA topoisomerase I [Pseudomonas aeruginosa].	24.82	411	244	13	74	459	260	630	2e-15	89.0
rs:WP_022178733	DNA topoisomerase [Firmicutes bacterium CAG:582].	23.10	407	241	15	77	449	282	650	2e-15	89.4
rs:WP_022325316	DNA topoisomerase [Clostridium sp. CAG:798].	23.40	423	271	11	47	454	226	610	2e-15	89.0
rs:WP_032973213	DNA topoisomerase I, partial [Stenotrophomonas maltophilia].	29.90	301	165	12	66	350	23	293	2e-15	89.0
rs:WP_022033928	DNA topoisomerase [Clostridium sp. CAG:710].	25.89	394	225	15	77	450	251	597	2e-15	89.0
tr:A0A031KIR6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	29.64	253	154	9	37	286	125	356	2e-15	87.8
rs:WP_004754292	DNA topoisomerase I [Acinetobacter sp. ANC 3789].	26.46	427	257	19	40	452	268	651	2e-15	89.4
rs:WP_039234307	DNA topoisomerase I [Clostridium sp. K25].	25.00	416	234	18	66	454	244	608	2e-15	89.0
rs:WP_024469514	hypothetical protein [Treponema pedis].	28.03	264	165	9	79	334	279	525	2e-15	89.0
rs:WP_024467148	hypothetical protein [Treponema pedis].	28.03	264	165	9	79	334	279	525	2e-15	89.0
rs:WP_041782277	DNA topoisomerase I [Mycobacterium chubuense].	26.02	392	236	13	41	410	292	651	2e-15	89.4
rs:WP_033644788	DNA topoisomerase, partial [Enterococcus faecium].	29.64	253	154	9	37	286	125	356	2e-15	87.4
rs:WP_030032216	hypothetical protein [Clostridium botulinum].	25.52	290	184	9	77	357	282	548	2e-15	89.4
rs:WP_036724648	DNA topoisomerase I [Paenibacillus sp. FSL R7-277].	23.95	430	263	15	50	457	227	614	2e-15	89.0
tr:H1HI78_FUSNU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHO75743.1}; Flags: Fragment;	26.29	194	137	3	40	233	193	380	2e-15	88.2
rs:WP_032016573	DNA topoisomerase I, partial [Acinetobacter baumannii].	26.35	406	247	17	50	446	1	363	2e-15	89.0
rs:WP_002480688	DNA topoisomerase 1 [Staphylococcus simulans].	22.57	421	258	12	54	452	231	605	2e-15	89.0
rs:WP_026518886	DNA topoisomerase I [Butyrivibrio sp. FCS006].	23.88	423	267	13	48	454	223	606	2e-15	89.0
rs:WP_002833092	DNA topoisomerase I [Pediococcus pentosaceus].	25.30	415	238	17	61	452	242	607	2e-15	89.0
tr:G9A4M7_RHIFH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.11	438	267	13	47	452	232	640	2e-15	89.4
tr:L0LHC8_RHITR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.72	441	265	14	47	452	232	640	2e-15	89.4
rs:WP_043363592	DNA topoisomerase I [Belnapia sp. F-4-1].	26.37	455	263	15	41	454	225	648	2e-15	89.4
rs:WP_048408300	DNA topoisomerase I [Chromobacterium sp. LK1].	23.69	477	264	14	49	459	233	675	2e-15	89.4
rs:XP_009311173	putative DNA topoisomerase III [Trypanosoma grayi].	27.49	371	223	13	44	403	208	543	2e-15	89.4
rs:WP_019805905	DNA topoisomerase I [Streptococcus mutans].	23.76	442	274	14	29	452	223	619	2e-15	89.0
rs:WP_047210202	DNA topoisomerase I [Streptococcus agalactiae].	22.65	437	275	14	34	452	229	620	2e-15	89.0
rs:WP_045078116	DNA topoisomerase I [Peptoniphilus sp. 1-1].	26.22	431	245	19	47	454	228	608	2e-15	89.0
tr:C1ABE5_GEMAT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.17	447	254	18	47	458	276	681	2e-15	89.4
rs:WP_022018119	DNA topoisomerase [Firmicutes bacterium CAG:129].	25.57	438	258	16	48	459	228	623	2e-15	89.4
rs:WP_005036280	DNA topoisomerase I [Holophaga foetida].	25.54	419	250	14	61	452	247	630	2e-15	89.4
rs:WP_021891351	DNA topoisomerase [Bacteroides sp. CAG:20].	27.09	299	182	7	40	334	212	478	2e-15	89.4
rs:WP_017955760	DNA topoisomerase I [actinobacterium SCGC AAA023-J06].	28.00	325	195	10	41	354	254	550	2e-15	89.4
tr:W4QCN6_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE29722.1};	35.07	134	85	1	260	391	1	134	2e-15	86.3
rs:WP_037107832	DNA topoisomerase I [Rhizobium sp. OK665].	25.40	441	262	14	47	452	230	638	2e-15	89.4
rs:WP_018750904	DNA topoisomerase I [Paenibacillus sanguinis].	24.54	432	259	16	50	457	227	615	2e-15	89.0
rs:WP_008967069	DNA topoisomerase I [Bradyrhizobium sp. STM 3843].	25.00	444	264	13	45	454	228	636	2e-15	89.4
rs:WP_045107952	DNA topoisomerase I [Pseudomonas sp. HMSC05H02].	24.82	411	244	14	74	459	260	630	2e-15	89.0
rs:WP_003140856	DNA topoisomerase I [Aerococcus viridans].	24.42	434	257	15	41	452	219	603	2e-15	89.0
tr:H0SCA3_9BRAD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.48	416	247	12	70	454	204	587	2e-15	89.4
rs:WP_021334812	DNA topoisomerase I subunit omega, partial [Corynebacterium diphtheriae].	25.90	332	210	8	31	354	249	552	2e-15	89.0
rs:WP_000259052	hypothetical protein [Streptococcus agalactiae].	26.67	345	219	11	59	399	263	577	2e-15	89.0
rs:WP_008189836	DNA topoisomerase I [Moorea producens].	28.80	316	178	11	77	379	284	565	2e-15	89.4
tr:G5JN01_STRCG	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.14	420	265	12	50	452	267	641	2e-15	89.0
rs:WP_034821739	DNA topoisomerase I [[Eubacterium] nodatum].	25.80	407	245	13	67	457	245	610	2e-15	89.0
rs:WP_011945076	DNA topoisomerase I [Orientia tsutsugamushi].	22.20	446	274	13	41	452	222	628	2e-15	89.4
tr:A0A0C7LRN9_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.24	313	205	10	49	357	252	539	2e-15	89.0
rs:WP_016951059	DNA topoisomerase I [Anabaena sp. PCC 7108].	26.02	342	205	10	77	401	285	595	2e-15	89.4
rs:WP_005696133	topoisomerase I [Haemophilus parainfluenzae].	25.40	378	235	14	77	446	290	628	2e-15	89.4
rs:WP_015856428	DNA topoisomerase I [Bartonella grahamii].	26.50	434	249	18	55	453	239	637	2e-15	89.4
rs:WP_045121537	DNA topoisomerase, partial [Fusobacterium nucleatum].	26.29	194	137	3	40	233	193	380	2e-15	88.2
rs:WP_018206960	DNA topoisomerase I [actinobacterium SCGC AAA024-D14].	28.00	325	195	10	41	354	254	550	2e-15	89.4
rs:WP_010623475	DNA topoisomerase I [Lactobacillus versmoldensis].	25.12	402	237	16	77	457	257	615	2e-15	89.0
tr:V6Z0Z2_STRAG	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.54	448	280	13	25	452	217	617	2e-15	89.0
rs:WP_032808585	DNA topoisomerase I [Oenococcus oeni].	24.56	399	242	12	70	452	254	609	2e-15	89.0
rs:WP_009408400	DNA topoisomerase I [Actinomyces sp. oral taxon 181].	25.00	388	241	11	23	386	228	589	2e-15	89.4
rs:WP_023015697	DNA topoisomerase I [Staphylococcus simulans].	22.57	421	258	12	54	452	231	605	2e-15	89.0
rs:WP_022177538	DNA topoisomerase [Oscillibacter sp. CAG:241].	26.03	438	256	15	48	459	230	625	2e-15	89.0
rs:WP_040363681	DNA topoisomerase I [Commensalibacter intestini].	23.71	447	273	11	41	452	225	638	2e-15	89.4
rs:WP_013261363	topoisomerase I [gamma proteobacterium HdN1].	25.62	441	253	16	36	452	255	644	2e-15	89.4
rs:XP_004843383	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Heterocephalus glaber].	22.96	466	267	16	40	453	263	688	2e-15	89.4
rs:WP_037563553	DNA topoisomerase I [Streptococcus agalactiae].	22.54	448	280	13	25	452	220	620	2e-15	89.0
rs:WP_023050986	hypothetical protein [Cetobacterium somerae].	24.37	439	263	15	40	458	227	616	2e-15	89.0
rs:WP_014410571	DNA topoisomerase I [Rickettsia parkeri].	25.06	415	244	16	65	449	250	627	2e-15	89.0
rs:WP_027347737	DNA topoisomerase I [Helcococcus sueciensis].	23.02	430	272	14	38	452	220	605	2e-15	89.0
rs:WP_019631896	DNA topoisomerase I [Actinomadura atramentaria].	24.77	327	199	10	42	354	248	541	2e-15	89.4
rs:WP_027827406	DNA topoisomerase I [Lactobacillus harbinensis].	22.54	426	261	12	55	457	233	612	2e-15	89.0
tr:A0A091R8G6_MERNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.97	438	261	15	25	434	182	575	2e-15	89.0
rs:WP_032816112	DNA topoisomerase I [Oenococcus oeni].	24.56	399	242	12	70	452	254	609	2e-15	89.0
rs:WP_012636779	DNA topoisomerase I [Thioalkalivibrio sulfidiphilus].	27.78	324	184	10	44	350	232	522	2e-15	89.0
rs:WP_014998125	topoisomerase I [Alteromonas macleodii].	26.04	457	255	18	8	446	239	630	2e-15	89.4
rs:WP_002960235	DNA topoisomerase III [Streptococcus sobrinus].	25.65	347	211	12	67	404	270	578	2e-15	89.0
rs:WP_027635064	DNA topoisomerase I [Clostridium butyricum].	23.23	409	252	12	66	454	242	608	2e-15	89.0
rs:WP_041677855	DNA topoisomerase I [Rhizobium tropici].	24.72	441	265	14	47	452	230	638	2e-15	89.4
rs:WP_023905388	DNA topoisomerase I [Xanthomonas hortorum].	28.91	377	209	15	66	416	254	597	2e-15	89.0
rs:WP_022217580	DNA topoisomerase [Bacteroides clarus CAG:160].	26.58	316	181	8	36	334	201	482	2e-15	89.0
tr:E2ZN56_9FIRM	SubName: Full=Topoisomerase DNA-binding C4 zinc finger domain protein {ECO:0000313|EMBL:EFQ05397.1};	32.64	239	130	9	215	445	4	219	2e-15	86.3
rs:WP_044954271	DNA topoisomerase III, partial [Faecalibacterium prausnitzii].	32.64	239	130	9	215	445	1	216	2e-15	86.3
tr:V8LW74_STRTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.45	409	238	14	65	452	270	628	2e-15	89.0
rs:WP_044061637	hypothetical protein, partial [Escherichia coli].	32.04	206	117	5	245	440	7	199	2e-15	85.5
rs:WP_010245426	DNA topoisomerase I [Peptoniphilus rhinitidis].	22.46	423	273	11	47	454	228	610	2e-15	89.0
rs:WP_014317501	DNA topoisomerase I [Corynebacterium diphtheriae].	25.90	332	210	8	31	354	249	552	2e-15	89.4
rs:WP_023103391	DNA topoisomerase I [Pseudomonas aeruginosa].	24.82	411	244	14	74	459	260	630	2e-15	89.0
rs:WP_027425646	DNA topoisomerase I [Lachnospiraceae bacterium NC2004].	26.62	402	230	16	74	454	247	604	2e-15	89.0
rs:WP_043618220	DNA topoisomerase I [Chromobacterium violaceum].	25.93	428	247	13	49	452	233	614	2e-15	89.0
rs:WP_035639421	hypothetical protein, partial [Bradyrhizobium sp. ORS 375].	25.48	416	247	12	70	454	220	603	2e-15	89.0
rs:WP_015262991	DNA topoisomerase I [Desulfitobacterium dichloroeliminans].	25.62	441	236	16	66	450	244	648	2e-15	89.0
tr:S7TBH8_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.29	424	263	13	47	452	240	623	2e-15	89.0
rs:WP_016971647	topoisomerase I [Pseudomonas tolaasii].	23.63	402	263	12	70	459	256	625	2e-15	89.0
rs:WP_041331875	DNA topoisomerase I, partial [Roseiflexus castenholzii].	24.34	493	249	15	47	452	234	689	2e-15	89.0
rs:WP_025323057	DNA topoisomerase I [Deferrisoma camini].	24.88	434	263	15	40	452	222	613	2e-15	89.0
rs:WP_027971276	DNA topoisomerase I [Streptococcus plurextorum].	24.20	438	266	14	34	452	228	618	2e-15	89.0
rs:WP_005666969	topoisomerase I [Haemophilus influenzae].	25.86	379	232	14	77	446	290	628	2e-15	89.0
rs:WP_023433784	DNA topoisomerase I [Lutibaculum baratangense].	24.72	449	260	16	43	452	225	634	2e-15	89.0
tr:G6EY22_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.71	447	273	11	41	452	183	596	2e-15	89.0
rs:WP_007964211	DNA topoisomerase I [Xanthomonas fuscans].	28.76	379	209	16	66	413	254	602	2e-15	89.0
tr:G4WVT3_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.86	417	243	15	45	449	215	581	2e-15	89.0
rs:WP_011759437	topoisomerase I [Shewanella amazonensis].	25.66	417	256	14	42	446	257	631	2e-15	89.0
rs:WP_046364506	DNA topoisomerase I [Mycobacterium obuense].	26.46	393	233	13	41	410	268	627	2e-15	89.0
tr:J9CNG0_9ZZZZ	SubName: Full=DNA topoisomerase TopB {ECO:0000313|EMBL:EJX01646.1};	23.98	392	261	11	5	387	213	576	2e-15	88.6
rs:WP_045915569	DNA topoisomerase I [Orientia tsutsugamushi].	22.20	446	274	13	41	452	222	628	2e-15	89.0
rs:WP_046983426	DNA topoisomerase I [Thermomonas brevis].	29.90	301	165	12	66	350	254	524	2e-15	89.0
rs:WP_039953520	DNA topoisomerase I [Bacteroides eggerthii].	26.50	317	180	9	36	334	201	482	2e-15	89.0
rs:NP_001167403	DNA topoisomerase 3-beta-1 [Salmo salar].	23.46	422	252	13	40	434	263	640	2e-15	89.0
rs:WP_026500741	DNA topoisomerase I [Bartonella grahamii].	26.50	434	249	18	55	453	239	637	2e-15	89.0
rs:WP_045050014	DNA topoisomerase I [Chromobacterium violaceum].	25.93	428	247	13	49	452	233	614	2e-15	89.0
rs:WP_032072421	DNA topoisomerase III [Clostridium botulinum].	24.94	385	236	13	77	446	282	628	2e-15	89.0
rs:WP_042610841	DNA topoisomerase I [Haemophilus influenzae].	25.86	379	232	14	77	446	290	628	2e-15	89.0
rs:WP_034140206	DNA topoisomerase I [Desulfosporosinus sp. BICA1-9].	24.77	436	266	15	41	454	218	613	2e-15	89.0
rs:WP_032136609	DNA topoisomerase I [Kingella sp. Sch538].	25.21	484	261	14	41	454	227	679	2e-15	89.0
rs:WP_037590747	DNA topoisomerase I [Streptococcus hyovaginalis].	22.49	449	279	13	25	452	220	620	2e-15	89.0
rs:WP_041418062	DNA topoisomerase I [Shewanella woodyi].	25.36	422	251	15	42	446	257	631	2e-15	89.0
rs:WP_025024322	DNA topoisomerase I [Lactobacillus nodensis].	24.31	432	265	13	46	457	227	616	2e-15	89.0
rs:WP_004461109	DNA topoisomerase III [Clostridium perfringens].	28.31	325	202	13	66	382	275	576	2e-15	89.0
rs:WP_039564478	DNA topoisomerase I, partial [Xanthomonas campestris].	28.76	379	209	16	66	413	254	602	2e-15	89.0
rs:XP_008945305	PREDICTED: DNA topoisomerase 3-beta-1, partial [Merops nubicus].	23.97	438	261	15	25	434	181	574	2e-15	89.0
rs:WP_004816257	DNA topoisomerase I [Anaerococcus hydrogenalis].	23.38	402	229	12	77	452	254	602	2e-15	89.0
rs:WP_045913310	DNA topoisomerase I [Orientia tsutsugamushi].	22.20	446	274	13	41	452	222	628	2e-15	89.0
rs:WP_003406572	DNA topoisomerase I [Clostridium butyricum].	23.23	409	252	12	66	454	242	608	2e-15	89.0
rs:WP_040804917	DNA topoisomerase I [Streptococcus criceti].	22.14	420	265	12	50	452	254	628	2e-15	89.0
rs:WP_011257487	DNA topoisomerase I [Xanthomonas oryzae].	28.54	396	215	17	66	426	254	616	2e-15	89.0
tr:I4BQ92_MYCCN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.02	392	236	13	41	410	279	638	2e-15	89.0
rs:WP_022560127	MULTISPECIES: DNA topoisomerase 1 [Xanthomonas].	28.76	379	209	16	66	413	254	602	2e-15	89.0
rs:WP_045912339	DNA topoisomerase I [Orientia tsutsugamushi].	22.20	446	274	13	41	452	222	628	2e-15	89.0
rs:WP_004674582	DNA topoisomerase I [Acinetobacter parvus].	26.12	356	216	11	40	384	267	586	2e-15	89.0
tr:A0A010YGE9_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.30	327	199	10	42	354	282	580	2e-15	89.0
rs:WP_003428420	MULTISPECIES: DNA topoisomerase [Clostridium].	23.23	409	252	12	66	454	242	608	2e-15	89.0
tr:G7JC55_MEDTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.26	441	268	15	39	450	265	668	2e-15	89.0
rs:WP_021078311	DNA topoisomerase I [Bradyrhizobium sp. DFCI-1].	25.41	425	254	12	61	454	244	636	2e-15	89.0
rs:WP_042048623	DNA topoisomerase I [Aeromonas simiae].	26.04	434	263	15	35	452	245	636	2e-15	89.0
rs:WP_032072733	DNA topoisomerase I TopA [uncultured bacterium].	26.98	430	259	18	38	459	215	597	2e-15	89.0
rs:WP_006010019	DNA topoisomerase I [Ehrlichia chaffeensis].	25.17	441	254	13	47	452	232	631	2e-15	89.0
rs:WP_029509338	DNA topoisomerase I [Leuconostoc lactis].	24.23	421	236	17	61	452	267	633	2e-15	89.0
tr:J8T6M4_PASMD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	58.73	63	26	0	69	131	79	141	2e-15	83.6
rs:WP_014323368	DNA topoisomerase I [Desulfovibrio desulfuricans].	24.23	421	259	14	47	451	230	606	2e-15	89.0
tr:B7AKT4_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.50	317	180	9	36	334	211	492	2e-15	89.0
rs:WP_019320014	DNA topoisomerase I [Streptococcus mutans].	23.76	442	274	14	29	452	223	619	2e-15	89.0
rs:WP_047340222	DNA topoisomerase I [Xanthomonas oryzae].	28.50	379	210	16	66	413	254	602	2e-15	89.0
rs:WP_008609910	topoisomerase I [Alishewanella aestuarii].	26.02	319	198	8	42	356	245	529	2e-15	89.0
rs:WP_014630190	DNA topoisomerase I [Thermus thermophilus].	26.33	414	230	15	61	454	264	622	2e-15	89.0
rs:WP_026520741	DNA topoisomerase I [Butyrivibrio sp. VCB2001].	23.88	423	267	13	48	454	223	606	2e-15	89.0
rs:WP_039431940	DNA topoisomerase I [Xanthomonas vasicola].	28.50	379	210	16	66	413	254	602	2e-15	89.0
rs:WP_007375380	DNA topoisomerase I [Pseudoalteromonas sp. Bsw20308].	26.47	374	227	12	36	395	251	590	2e-15	89.0
rs:WP_019396332	DNA topoisomerase I [Pseudomonas aeruginosa].	25.06	411	243	14	74	459	260	630	2e-15	88.6
rs:WP_035860044	DNA topoisomerase I [Cryptosporangium arvum].	26.30	327	199	10	42	354	257	555	2e-15	89.0
rs:WP_039615782	DNA topoisomerase I [Rhodobacteraceae bacterium PD-2].	26.99	478	246	18	41	454	225	663	2e-15	89.0
rs:WP_012512224	DNA topoisomerase I [Stenotrophomonas maltophilia].	30.23	301	164	12	66	350	254	524	2e-15	89.0
rs:XP_002057453	GJ18138 [Drosophila virilis].	25.11	446	260	15	40	451	256	661	2e-15	89.4
rs:WP_022378022	GTP-sensing transcriptional pleiotropic repressor CodY [Clostridium sp. CAG:62].	23.30	455	272	13	38	454	194	609	2e-15	88.6
tr:A0A061NDD9_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	26.18	359	212	13	50	387	98	424	2e-15	88.6
rs:WP_046465282	DNA topoisomerase I [Staphylococcus equorum].	23.38	432	270	14	40	452	217	606	2e-15	88.6
rs:WP_035474507	DNA topoisomerase I [Gammaproteobacteria bacterium MFB021].	27.00	400	226	18	70	452	291	641	2e-15	89.0
rs:WP_044142794	DNA topoisomerase I [Anaplasma phagocytophilum].	25.75	431	249	16	54	452	239	630	2e-15	89.0
rs:WP_021458862	DNA topoisomerase I [Staphylococcus sp. EGD-HP3].	23.80	395	239	14	77	452	254	605	2e-15	88.6
rs:XP_008328484	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Cynoglossus semilaevis].	24.09	465	267	14	24	450	289	705	2e-15	89.0
rs:WP_046781988	DNA topoisomerase I [Lactococcus lactis].	22.27	422	262	12	50	452	246	620	2e-15	89.0
rs:WP_036705590	hypothetical protein, partial [Paracoccus sanguinis].	25.34	438	251	15	60	454	241	645	2e-15	89.0
rs:WP_025011036	DNA topoisomerase I [Shewanella algae].	28.61	339	193	13	65	388	279	583	2e-15	89.0
rs:WP_012814316	DNA topoisomerase I [Candidatus Methylomirabilis oxyfera].	25.28	443	266	13	41	452	219	627	2e-15	89.0
tr:Q895L4_CLOTE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.18	397	240	12	77	454	256	610	2e-15	88.6
rs:XP_008328483	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Cynoglossus semilaevis].	24.09	465	267	14	24	450	289	705	2e-15	89.0
rs:WP_035745753	DNA topoisomerase I [Haematobacter missouriensis].	25.92	436	256	15	47	454	228	624	2e-15	89.0
rs:WP_010481170	DNA topoisomerase I [[Pseudomonas] geniculata].	29.90	301	165	12	66	350	254	524	2e-15	89.0
rs:WP_036736860	hypothetical protein, partial [Paracoccus sanguinis].	25.34	438	251	15	60	454	241	645	2e-15	89.0
rs:WP_029081047	DNA topoisomerase I [Bradyrhizobium sp. th.b2].	24.94	425	256	12	61	454	244	636	2e-15	89.0
tr:B1KNL0_SHEWM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.36	422	251	15	42	446	273	647	2e-15	89.0
rs:WP_043961495	DNA topoisomerase I [Micromonospora carbonacea].	26.58	365	214	14	42	386	261	591	2e-15	89.0
rs:WP_021799565	DNA topoisomerase I [Anaplasma phagocytophilum].	25.75	431	249	16	54	452	239	630	2e-15	89.0
rs:WP_003380888	topoisomerase I [Pseudomonas syringae].	26.41	409	248	15	49	446	261	627	2e-15	89.0
rs:WP_004644771	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	24.55	444	274	16	22	459	216	604	2e-15	89.0
rs:WP_032958266	DNA topoisomerase I [Stenotrophomonas maltophilia].	29.90	301	165	12	66	350	254	524	2e-15	89.0
rs:WP_047660482	DNA topoisomerase III, partial [Escherichia coli].	35.07	134	83	1	37	170	245	374	2e-15	87.0
tr:A0A0C2M7A6_9CYAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.87	382	232	10	41	398	253	603	2e-15	89.0
rs:WP_014648569	DNA topoisomerase I [Stenotrophomonas maltophilia].	29.90	301	165	12	66	350	254	524	2e-15	89.0
rs:WP_003787925	DNA topoisomerase I [Kingella kingae].	25.21	484	261	14	41	454	227	679	2e-15	89.0
rs:WP_006934918	DNA topoisomerase I [Labrenzia aggregata].	26.11	471	276	19	23	452	202	641	2e-15	89.0
rs:WP_035800099	DNA topoisomerase I [Kitasatospora mediocidica].	26.46	325	196	11	42	354	270	563	2e-15	89.0
rs:WP_041569554	hypothetical protein, partial [Chloracidobacterium thermophilum].	25.96	416	241	15	61	452	263	635	2e-15	88.6
rs:WP_002351757	DNA topoisomerase I [Streptococcus mutans].	23.53	442	275	14	29	452	223	619	2e-15	88.6
rs:WP_048101002	DNA topoisomerase I [Acidiplasma sp. MBA-1].	24.06	345	219	11	38	377	236	542	2e-15	89.0
rs:WP_009222995	DNA topoisomerase I [Paenibacillus sp. oral taxon 786].	24.07	432	263	17	49	457	226	615	2e-15	88.6
rs:WP_025648226	DNA topoisomerase I [Clostridium perfringens].	25.23	432	252	17	47	454	224	608	2e-15	88.6
rs:WP_014410140	DNA topoisomerase I [Rickettsia montanensis].	25.06	419	239	17	65	449	250	627	2e-15	89.0
rs:WP_011048772	DNA topoisomerase I [Ruegeria pomeroyi].	24.78	464	258	15	47	454	231	659	2e-15	89.0
rs:WP_035676396	DNA topoisomerase I [Azospirillum brasilense].	26.93	479	272	16	16	454	203	643	3e-15	89.0
rs:WP_010340683	DNA topoisomerase I [Xanthomonas sacchari].	29.90	301	165	12	66	350	254	524	3e-15	89.0
rs:WP_009622375	DNA topoisomerase I [Desulfosporosinus sp. OT].	24.77	432	269	12	45	457	222	616	3e-15	88.6
rs:WP_038314451	DNA topoisomerase I [Kingella kingae].	25.21	484	261	14	41	454	227	679	3e-15	89.0
rs:WP_034038751	DNA topoisomerase I [Pseudomonas aeruginosa].	25.37	410	243	13	74	459	260	630	3e-15	88.6
rs:WP_045282656	DNA topoisomerase I [Shewanella algae].	28.61	339	193	13	65	388	279	583	3e-15	89.0
rs:WP_027218029	DNA topoisomerase I [Butyrivibrio fibrisolvens].	23.99	421	265	11	50	454	232	613	3e-15	88.6
tr:J4SHF3_9MYCO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.30	384	231	11	37	399	247	599	3e-15	89.0
tr:F9PSB8_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.40	414	244	13	66	457	5	371	3e-15	88.2
rs:WP_046416095	DNA topoisomerase I [Bacteroides sp. UNK.MGS-13].	27.09	299	182	7	40	334	212	478	3e-15	89.0
rs:WP_016945597	DNA topoisomerase I [Rickettsia conorii].	24.76	420	239	16	65	449	250	627	3e-15	89.0
rs:WP_012148895	DNA topoisomerase I [Rickettsia canadensis].	24.09	411	253	14	65	449	250	627	3e-15	89.0
tr:K1U9G8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC78843.1}; Flags: Fragment;	34.88	172	97	4	232	398	1	162	3e-15	85.9
rs:WP_022273096	DNA topoisomerase [Clostridium sp. CAG:58].	23.30	455	289	12	17	454	202	613	3e-15	88.6
rs:WP_016897101	DNA topoisomerase I [Aerococcus viridans].	24.71	429	246	17	49	452	227	603	3e-15	88.6
rs:WP_008802445	type I topoisomease [Fusobacterium nucleatum].	24.69	405	262	15	60	452	255	628	3e-15	88.6
rs:WP_038823346	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	25.06	411	243	14	74	459	147	517	3e-15	88.2
rs:WP_044294085	DNA topoisomerase I [Robinsoniella peoriensis].	23.00	426	275	12	48	457	227	615	3e-15	88.6
rs:WP_008134073	MULTISPECIES: topoisomerase I [Gammaproteobacteria].	26.47	374	227	12	36	395	251	590	3e-15	89.0
rs:WP_005772516	DNA topoisomerase III, partial [Pseudomonas amygdali].	36.60	153	84	3	302	452	2	143	3e-15	84.0
rs:WP_012262322	DNA topoisomerase I [Rickettsia rickettsii].	25.30	415	243	16	65	449	250	627	3e-15	88.6
rs:WP_039035873	DNA topoisomerase I [Shewanella sp. ECSMB14102].	28.02	339	195	12	65	388	279	583	3e-15	89.0
rs:WP_035124882	DNA topoisomerase I [Clostridium tetani].	24.18	397	240	12	77	454	254	608	3e-15	88.6
rs:WP_002579620	DNA topoisomerase I [Clostridium butyricum].	23.23	409	252	12	66	454	242	608	3e-15	88.6
rs:WP_039413639	DNA topoisomerase I [Xanthomonas campestris].	28.76	379	209	16	66	413	254	602	3e-15	89.0
rs:WP_025981576	DNA topoisomerase I [Pseudomonas aeruginosa].	24.82	411	244	14	74	459	260	630	3e-15	88.6
tr:W1MU77_PSEAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.06	411	243	14	74	459	212	582	3e-15	88.6
sp:TOP1_RICFE	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.24	412	247	16	65	449	250	627	3e-15	88.6
rs:WP_030764024	DNA topoisomerase I [Streptomyces sp. NRRL F-2664].	26.27	335	198	11	35	354	256	556	3e-15	89.0
rs:WP_040527233	DNA topoisomerase I [Gordonia paraffinivorans].	26.23	385	223	13	35	389	251	604	3e-15	89.0
rs:WP_017684584	topoisomerase I [Pseudomonas syringae].	26.41	409	248	15	49	446	261	627	3e-15	89.0
rs:WP_019678111	DNA topoisomerase I [Ruminococcus flavefaciens].	24.81	395	239	11	77	452	255	610	3e-15	88.6
rs:XP_001658595	AAEL007683-PA [Aedes aegypti].	24.04	445	270	15	37	452	277	682	3e-15	89.0
rs:WP_028669789	DNA topoisomerase I [Saccharospirillum impatiens].	26.68	386	218	15	77	446	295	631	3e-15	89.0
rs:WP_005697517	MULTISPECIES: topoisomerase I [Haemophilus].	25.66	378	234	14	77	446	290	628	3e-15	89.0
rs:WP_005813282	DNA topoisomerase I [Desulfitobacterium hafniense].	27.05	414	237	16	66	457	244	614	3e-15	88.6
rs:WP_010934214	DNA topoisomerase I [Corynebacterium diphtheriae].	25.90	332	210	8	31	354	249	552	3e-15	89.0
tr:A0A051TNA3_MYCTX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.30	384	231	11	37	399	247	599	3e-15	89.0
rs:WP_025579645	DNA topoisomerase I [Blautia wexlerae].	24.71	425	261	13	48	454	226	609	3e-15	88.6
rs:WP_004847177	DNA topoisomerase I [[Ruminococcus] torques].	23.89	427	269	11	48	457	227	614	3e-15	88.6
rs:WP_008705704	MULTISPECIES: DNA topoisomerase I [Clostridiales].	24.71	425	261	13	48	454	226	609	3e-15	88.6
rs:WP_004843019	DNA topoisomerase I [[Ruminococcus] gnavus].	24.00	425	271	12	48	457	227	614	3e-15	88.6
rs:XP_002986296	hypothetical protein SELMODRAFT_123748, partial [Selaginella moellendorffii].	23.86	415	256	12	65	449	253	637	3e-15	88.6
rs:WP_038132716	DNA topoisomerase I [Thioclava sp. DT23-4].	24.21	475	264	13	41	454	222	661	3e-15	89.0
rs:WP_017660177	DNA topoisomerase I [Geitlerinema sp. PCC 7105].	26.36	368	223	12	25	377	230	564	3e-15	89.0
rs:WP_004649883	DNA topoisomerase I [Acinetobacter bohemicus].	25.00	320	202	8	40	356	267	551	3e-15	89.0
rs:WP_021087516	DNA topoisomerase I [Campylobacter concisus].	26.65	394	221	16	77	450	254	599	3e-15	88.6
rs:WP_016409792	DNA topoisomerase [Clostridium sp. CAG:1024].	24.01	479	298	14	1	452	170	609	3e-15	88.6
rs:WP_019070269	DNA topoisomerase I [Streptomyces sp. R1-NS-10].	26.61	342	195	12	35	354	250	557	3e-15	89.0
rs:WP_021092863	DNA topoisomerase I [Campylobacter concisus].	26.84	395	219	16	77	450	254	599	3e-15	88.6
rs:WP_022398991	GTP-sensing transcriptional pleiotropic repressor CodY [Roseburia sp. CAG:471].	23.65	427	272	11	47	457	226	614	3e-15	88.6
rs:WP_005710553	DNA topoisomerase I [Lactobacillus rhamnosus].	23.96	434	260	13	43	452	223	610	3e-15	88.6
rs:WP_027205421	DNA topoisomerase I [Butyrivibrio fibrisolvens].	24.47	421	263	12	50	454	232	613	3e-15	88.6
rs:WP_043571895	DNA topoisomerase I [Chromobacterium subtsugae].	26.53	426	247	13	49	452	233	614	3e-15	88.6
rs:WP_047258136	DNA topoisomerase I [Chromobacterium subtsugae].	26.53	426	247	13	49	452	233	614	3e-15	88.6
rs:WP_047243105	DNA topoisomerase I [Chromobacterium subtsugae].	26.53	426	247	13	49	452	233	614	3e-15	88.6
rs:WP_009500471	topoisomerase I [Haemophilus sp. oral taxon 851].	25.59	379	233	14	77	446	290	628	3e-15	88.6
rs:WP_020696273	hypothetical protein [Reyranella massiliensis].	25.48	420	239	16	70	452	253	635	3e-15	89.0
rs:WP_007540097	DNA topoisomerase I [Candidatus Aquiluna sp. IMCC13023].	28.37	349	189	12	35	358	234	546	3e-15	88.6
rs:WP_008954815	DNA topoisomerase I [Pseudogulbenkiania ferrooxidans].	25.92	436	267	14	31	452	221	614	3e-15	88.6
rs:XP_006581776	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Glycine max].	24.10	444	271	16	39	451	261	669	3e-15	89.0
rs:WP_003560399	DNA topoisomerase I [Lactobacillus buchneri].	25.37	410	235	18	65	452	267	627	3e-15	88.6
rs:WP_035109892	DNA topoisomerase I [Clostridium tetani].	24.18	397	240	12	77	454	254	608	3e-15	88.6
rs:WP_039758711	DNA topoisomerase I [Bartonella queenslandensis].	27.19	434	241	19	55	452	239	633	3e-15	88.6
rs:WP_038320683	DNA topoisomerase I [Kingella kingae].	25.21	484	261	14	41	454	227	679	3e-15	88.6
rs:WP_042177548	DNA topoisomerase I [Paenibacillus sp. FSL R7-0331].	24.42	434	256	16	50	457	227	614	3e-15	88.6
rs:WP_008983002	topoisomerase I [Alishewanella agri].	27.21	283	170	8	77	356	280	529	3e-15	88.6
rs:WP_012698584	DNA topoisomerase I [Laribacter hongkongensis].	26.23	427	249	14	50	452	234	618	3e-15	88.6
rs:WP_009298158	MULTISPECIES: DNA topoisomerase I [Clostridiales].	24.82	427	264	14	48	457	230	616	3e-15	88.6
rs:WP_004680559	DNA topoisomerase I [Acinetobacter parvus].	26.12	356	216	11	40	384	267	586	3e-15	88.6
rs:WP_027720616	DNA topoisomerase I [Desulfovibrio zosterae].	24.41	422	255	13	47	450	225	600	3e-15	88.6
rs:WP_047764708	DNA topoisomerase I [Kiloniella spongiae].	25.06	423	258	14	60	452	244	637	3e-15	88.6
rs:WP_013889909	DNA topoisomerase I [Helicobacter bizzozeronii].	24.65	434	259	13	41	454	255	640	3e-15	88.6
rs:WP_021084556	DNA topoisomerase I [Campylobacter concisus].	26.90	394	220	16	77	450	254	599	3e-15	88.6
rs:WP_021151812	DNA topoisomerase I [Streptococcus sp. HSISS3].	23.81	441	264	15	34	452	238	628	3e-15	88.6
rs:WP_047381285	MULTISPECIES: DNA topoisomerase I [Cetobacterium].	25.61	367	218	12	40	387	216	546	3e-15	88.6
rs:WP_008683354	DNA topoisomerase I [Desulfovibrio sp. 3_1_syn3].	23.00	413	278	8	47	452	225	604	3e-15	88.6
rs:WP_033120310	DNA topoisomerase I [Oscillibacter sp. ER4].	26.21	435	260	16	48	459	228	624	3e-15	88.6
rs:WP_021335436	DNA topoisomerase I subunit omega [Corynebacterium diphtheriae].	25.90	332	210	8	31	354	249	552	3e-15	89.0
rs:WP_028257373	DNA topoisomerase I [Veillonella montpellierensis].	22.45	441	270	11	38	454	284	676	3e-15	88.6
tr:A0A0C6FHI5_PSEAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.30	411	242	14	74	459	212	582	3e-15	88.2
rs:WP_040370877	DNA topoisomerase I [Desulfovibrio alkalitolerans].	24.29	424	263	13	47	452	233	616	3e-15	88.6
tr:A0A099VQ59_9HELI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	23.74	438	262	14	41	454	24	413	3e-15	88.2
rs:WP_018210926	DNA topoisomerase I [Desulfitobacterium hafniense].	27.05	414	237	16	66	457	244	614	3e-15	88.6
rs:WP_023098077	DNA topoisomerase I [Pseudomonas aeruginosa].	25.06	411	243	14	74	459	260	630	3e-15	88.6
rs:WP_027431366	DNA topoisomerase I [Lachnospira multipara].	24.07	428	269	13	47	457	226	614	3e-15	88.6
tr:F5TCL2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	24.88	414	242	14	66	457	92	458	3e-15	88.2
rs:WP_018325938	DNA topoisomerase I [Rhizobium giardinii].	25.23	440	264	14	47	452	230	638	3e-15	88.6
rs:WP_017805692	topoisomerase I [Avibacterium paragallinarum].	26.05	380	230	15	77	446	290	628	3e-15	88.6
rs:WP_038329203	DNA topoisomerase I [Kingella kingae].	25.21	484	261	14	41	454	227	679	3e-15	88.6
rs:WP_022969384	DNA topoisomerase I [Arenimonas oryziterrae].	30.10	299	163	10	69	350	255	524	3e-15	88.6
rs:WP_043734521	DNA topoisomerase I [Lactococcus lactis].	22.27	422	262	12	50	452	250	624	3e-15	88.6
rs:WP_019332831	topoisomerase I [Pseudomonas syringae].	26.41	409	248	15	49	446	261	627	3e-15	88.6
tr:A0A0E1SR17_HAEIF	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EDK12148.1};	44.23	104	58	0	293	396	1	104	3e-15	83.2
rs:WP_006731013	DNA topoisomerase [Lactobacillus iners].	28.40	243	160	6	159	398	3	234	3e-15	85.1
rs:WP_013784485	topoisomerase I [Alteromonas sp. SN2].	27.37	380	214	13	8	378	239	565	3e-15	88.6
rs:WP_041523467	DNA topoisomerase I [Gilvimarinus agarilyticus].	27.06	425	247	18	47	452	263	643	3e-15	88.6
rs:WP_017121437	DNA topoisomerase I [Xanthomonas vasicola].	28.50	379	210	16	66	413	254	602	3e-15	88.6
tr:A7NJW2_ROSCS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.34	493	249	15	47	452	234	689	3e-15	88.6
rs:WP_005713869	DNA topoisomerase I [Lactobacillus rhamnosus].	23.96	434	260	13	43	452	223	610	3e-15	88.6
gp:CP002094_1249	DNA topoisomerase I [Lactococcus lactis subsp. cremoris NZ9000]	22.27	422	262	12	50	452	229	603	3e-15	88.6
rs:WP_002735765	DNA topoisomerase I [Microcystis aeruginosa].	24.34	378	238	11	41	401	249	595	3e-15	88.6
rs:WP_004561483	DNA topoisomerase I [Lactobacillus hilgardii].	25.37	410	235	18	65	452	267	627	3e-15	88.6
rs:WP_016371159	DNA topoisomerase I [Lactobacillus paracasei].	23.84	432	263	11	43	452	223	610	3e-15	88.6
rs:WP_033901430	DNA topoisomerase I [Pseudomonas sp. FH1].	24.94	397	252	14	77	459	263	627	3e-15	88.2
rs:WP_047922757	DNA topoisomerase I, partial [Neisseria gonorrhoeae].	25.46	432	261	13	41	452	225	615	3e-15	88.6
rs:WP_016868952	hypothetical protein, partial [Fischerella muscicola].	26.92	416	241	16	40	435	241	613	3e-15	88.2
rs:WP_019281329	hypothetical protein [Vibrio anguillarum].	26.03	411	233	16	70	458	237	598	3e-15	88.6
tr:W8IA30_ENSAD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.83	443	262	15	47	452	232	640	3e-15	88.6
rs:WP_023101571	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	25.06	411	243	14	74	459	260	630	3e-15	88.2
rs:WP_010381554	topoisomerase I [Pseudoalteromonas rubra].	25.96	389	243	13	66	446	280	631	3e-15	88.6
tr:X8IV48_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.37	255	147	10	37	286	225	456	3e-15	87.8
rs:WP_014316296	DNA topoisomerase I [Corynebacterium diphtheriae].	25.90	332	210	8	31	354	249	552	3e-15	88.6
rs:WP_014302829	DNA topoisomerase I [Corynebacterium diphtheriae].	25.90	332	210	8	31	354	249	552	3e-15	88.6
rs:WP_047699160	DNA topoisomerase I [Xanthomonas campestris].	28.50	379	210	16	66	413	254	602	3e-15	88.6
rs:WP_038307892	DNA topoisomerase I [Kingella kingae].	25.21	484	261	14	41	454	227	679	3e-15	88.6
rs:WP_042199154	DNA topoisomerase I [Paenibacillus sp. G4].	24.42	434	256	16	50	457	227	614	3e-15	88.6
rs:WP_044487619	DNA topoisomerase I [Mycobacterium tuberculosis].	26.30	384	231	11	37	399	267	619	3e-15	88.6
tr:A0A078AG43_STYLE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.08	311	194	8	73	377	487	764	3e-15	88.6
tr:D4LCS4_RUMC1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.17	429	253	16	48	452	226	610	3e-15	88.6
rs:WP_045916818	DNA topoisomerase I [Orientia tsutsugamushi].	22.20	446	274	13	41	452	222	628	3e-15	88.6
rs:WP_017729828	hypothetical protein [Nafulsella turpanensis].	26.96	293	179	7	47	335	219	480	3e-15	88.6
rs:WP_004756177	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	26.12	356	216	11	40	384	267	586	3e-15	88.6
rs:WP_012491591	MULTISPECIES: DNA topoisomerase I [Lactobacillus casei group].	23.84	432	263	11	43	452	223	610	3e-15	88.6
rs:WP_027297021	MULTISPECIES: DNA topoisomerase I [Robinsoniella].	23.00	426	275	12	48	457	227	615	3e-15	88.6
rs:WP_005538876	topoisomerase I [Aggregatibacter actinomycetemcomitans].	23.94	376	243	11	77	446	290	628	3e-15	88.6
rs:WP_018972214	DNA topoisomerase I [Rudaea cellulosilytica].	28.13	327	179	12	45	350	233	524	3e-15	88.6
rs:WP_010376861	DNA topoisomerase I [Xanthomonas campestris].	28.50	379	210	16	66	413	254	602	3e-15	88.6
rs:WP_040313025	DNA topoisomerase I [Actinomyces coleocanis].	29.19	346	179	12	43	356	250	561	3e-15	88.6
rs:WP_040630636	DNA topoisomerase I [Mycobacterium colombiense].	26.30	384	231	11	37	399	267	619	3e-15	88.6
rs:WP_029018600	DNA topoisomerase I [actinobacterium SCGC AAA028-I14].	28.00	325	195	9	41	354	254	550	3e-15	88.6
rs:WP_010363005	DNA topoisomerase I [Xanthomonas vasicola].	25.47	428	263	14	46	459	229	614	3e-15	88.6
tr:H2Z239_CIOSA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.52	420	248	15	60	451	284	662	3e-15	88.6
rs:WP_028780491	DNA topoisomerase I [Shewanella sp. 38A_GOM-205m].	28.02	339	195	12	65	388	279	583	3e-15	88.6
rs:WP_008797619	type I topoisomerase [Fusobacterium nucleatum].	24.94	405	261	15	60	452	255	628	3e-15	88.2
rs:WP_041699504	DNA topoisomerase I, partial [Pseudanabaena sp. PCC 7367].	25.56	360	221	12	41	387	250	575	3e-15	88.6
rs:WP_036380219	DNA topoisomerase, partial [Mogibacterium timidum].	31.37	255	147	10	37	286	225	456	3e-15	87.8
rs:WP_033790335	DNA topoisomerase I [Pantoea sp. FF5].	26.85	391	230	15	77	452	284	633	3e-15	88.6
rs:WP_046003777	DNA topoisomerase I [Pseudoalteromonas rubra].	26.26	396	233	14	66	446	280	631	3e-15	88.6
rs:WP_011272639	topoisomerase I [Haemophilus influenzae].	25.86	379	232	14	77	446	290	628	3e-15	88.6
rs:WP_038321536	DNA topoisomerase I [Kingella kingae].	25.21	484	261	14	41	454	227	679	3e-15	88.6
tr:C0W269_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	29.19	346	179	12	43	356	256	567	3e-15	88.6
rs:WP_014307889	DNA topoisomerase I [Corynebacterium diphtheriae].	25.90	332	210	8	31	354	249	552	3e-15	88.6
rs:WP_038441141	DNA topoisomerase I [Haemophilus influenzae].	25.86	379	232	14	77	446	290	628	3e-15	88.6
rs:WP_017115144	DNA topoisomerase I [Xanthomonas vasicola].	28.50	379	210	16	66	413	254	602	3e-15	88.6
tr:M3TUR3_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.23	385	223	13	35	389	234	587	3e-15	88.6
rs:WP_031861946	DNA topoisomerase III, partial [Staphylococcus aureus].	24.81	262	176	6	35	295	109	350	3e-15	86.7
rs:WP_041953509	DNA topoisomerase I [Parvimonas micra].	24.88	414	242	14	66	457	246	612	3e-15	88.2
rs:WP_038040953	DNA topoisomerase I [Thermorudis peleae].	24.10	444	242	16	69	449	248	659	3e-15	88.2
tr:H2YRK7_CIOSA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.29	350	220	9	39	378	279	593	3e-15	88.2
rs:WP_025426616	DNA topoisomerase I [Ensifer adhaerens].	24.83	443	262	15	47	452	230	638	3e-15	88.6
rs:WP_044495906	DNA topoisomerase I, partial [Peptoclostridium difficile].	24.83	298	179	7	166	454	64	325	3e-15	87.4
rs:WP_011835151	DNA topoisomerase I [Lactococcus lactis].	22.27	422	262	12	50	452	248	622	3e-15	88.2
rs:WP_016709380	topoisomerase I [Pseudoalteromonas haloplanktis].	24.64	418	259	12	42	446	257	631	3e-15	88.6
rs:WP_011160653	topoisomerase I [Onion yellows phytoplasma].	23.87	419	257	14	47	450	217	588	3e-15	88.2
rs:WP_046124918	DNA topoisomerase I [Lactococcus lactis].	22.27	422	262	12	50	452	248	622	3e-15	88.2
sp:TOP1_RICCN	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.30	415	243	16	65	449	250	627	3e-15	88.6
rs:WP_047220985	DNA topoisomerase I [Orientia tsutsugamushi].	22.20	446	274	13	41	452	222	628	3e-15	88.6
rs:WP_005419627	DNA topoisomerase I [Stenotrophomonas maltophilia].	29.57	301	166	12	66	350	254	524	3e-15	88.6
rs:WP_015186585	DNA topoisomerase I [Gloeocapsa sp. PCC 7428].	25.60	336	214	7	41	370	255	560	3e-15	88.6
rs:WP_046438496	DNA topoisomerase I [Corynebacterium kutscheri].	25.37	335	209	8	30	351	247	553	3e-15	88.6
rs:WP_022754505	DNA topoisomerase I [Butyrivibrio fibrisolvens].	24.47	421	263	12	50	454	232	613	3e-15	88.2
rs:WP_038439864	DNA topoisomerase I [Haemophilus influenzae].	25.86	379	232	14	77	446	290	628	3e-15	88.6
tr:H2Z235_CIOSA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.52	420	248	15	60	451	320	698	3e-15	88.6
rs:WP_003850467	DNA topoisomerase I [Corynebacterium diphtheriae].	25.90	332	210	8	31	354	249	552	3e-15	88.6
rs:WP_014306395	DNA topoisomerase I [Corynebacterium diphtheriae].	25.90	332	210	8	31	354	249	552	3e-15	88.6
rs:WP_012471296	DNA topoisomerase I [Geobacter lovleyi].	25.46	436	259	15	43	452	227	622	3e-15	88.6
tr:A0A090RGX5_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	36.59	123	75	2	54	173	2	124	3e-15	82.8
rs:WP_034968372	DNA topoisomerase I [Campylobacter mucosalis].	25.76	427	243	17	47	450	224	599	3e-15	88.2
tr:E6QPP2_9ZZZZ	SubName: Full=DNA topoisomerase 1 (DNA topoisomerase I) (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) {ECO:0000313|EMBL:CBI09213.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI09213.1};	25.88	425	250	19	48	450	232	613	3e-15	88.6
rs:WP_036313419	DNA topoisomerase I [Microbacterium oleivorans].	28.32	339	195	13	51	377	269	571	3e-15	88.6
rs:WP_014659216	DNA topoisomerase I [Helicobacter cetorum].	24.65	430	256	15	41	450	218	599	3e-15	88.2
rs:WP_040919489	DNA topoisomerase I, partial [Leptonema illini].	22.62	451	299	11	18	451	213	630	3e-15	88.2
rs:WP_014364053	DNA topoisomerase I [Rickettsia canadensis].	24.09	411	253	14	65	449	250	627	3e-15	88.6
rs:WP_008693641	type I topoisomease [Fusobacterium nucleatum].	24.50	449	288	17	24	452	211	628	3e-15	88.2
tr:C0D9F9_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.24	425	269	11	48	457	239	625	3e-15	88.2
rs:WP_038310428	DNA topoisomerase I [Kingella kingae].	25.21	484	261	14	41	454	227	679	3e-15	88.6
rs:WP_047694650	DNA topoisomerase I [Xanthomonas sp. Nyagatare].	28.50	379	210	16	66	413	254	602	3e-15	88.6
gp:CP007064_1426	DNA topoisomerase III [Fusobacterium nucleatum subsp. vincentii 3_1_27]	24.94	405	261	15	60	452	251	624	3e-15	88.2
rs:WP_011227691	DNA topoisomerase I [Thermus thermophilus].	26.09	414	231	15	61	454	264	622	3e-15	88.6
tr:H2Z243_CIOSA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.83	391	230	14	39	414	153	498	3e-15	88.2
rs:WP_009815756	DNA topoisomerase I [Roseovarius sp. 217].	25.46	487	259	20	34	454	205	653	3e-15	88.6
tr:F7LSI9_9BACE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGN05988.1};	31.72	186	117	6	215	396	3	182	3e-15	85.5
rs:WP_016514708	DNA topoisomerase 1 [Microcystis aeruginosa].	24.34	378	238	11	41	401	249	595	3e-15	88.6
rs:WP_032893455	DNA topoisomerase [Fusobacterium nucleatum].	24.05	449	290	17	24	452	211	628	3e-15	88.2
rs:WP_046836243	DNA topoisomerase I [Staphylococcus succinus].	23.15	432	270	14	40	452	217	605	3e-15	88.2
rs:WP_025029833	DNA topoisomerase I [Nitratireductor aquibiodomus].	25.74	439	254	18	47	449	230	632	3e-15	88.6
tr:A0A0E9F909_CHLTH	SubName: Full=DNA topoisomerase I-fused to SWI domain {ECO:0000313|EMBL:CRH78105.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRH78105.1};	25.19	385	238	17	77	450	125	470	3e-15	87.8
rs:XP_002379355	DNA topoisomerase III, putative [Aspergillus flavus NRRL3357].	26.30	346	195	9	45	369	267	573	3e-15	88.2
rs:XP_012555024	PREDICTED: DNA topoisomerase 3-beta-1-like [Hydra vulgaris].	23.91	435	263	15	40	453	256	643	3e-15	88.6
tr:D1J990_9ARCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.19	414	276	11	46	454	248	624	3e-15	88.2
tr:K9SJI8_9CYAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.56	360	221	12	41	387	250	575	3e-15	88.6
rs:WP_021674657	DNA topoisomerase, partial [Peptostreptococcaceae bacterium oral taxon 113].	30.93	236	132	8	66	294	66	277	3e-15	85.5
tr:G2LH23_CHLTF	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.96	416	241	15	61	452	263	635	3e-15	88.6
rs:WP_012408434	DNA topoisomerase I [Nostoc punctiforme].	23.52	421	266	13	40	444	242	622	3e-15	88.2
rs:WP_003553968	DNA topoisomerase I [Lactobacillus brevis].	25.37	410	235	18	65	452	267	627	4e-15	88.2
rs:WP_004920177	MULTISPECIES: topoisomerase I [Acinetobacter].	26.06	426	260	18	40	452	269	652	4e-15	88.6
rs:WP_010370069	DNA topoisomerase I [Xanthomonas vasicola].	28.50	379	210	16	66	413	254	602	4e-15	88.6
rs:WP_034036278	DNA topoisomerase I [Pseudomonas aeruginosa].	25.12	410	244	13	74	459	260	630	4e-15	88.2
rs:WP_044147783	DNA topoisomerase I [Ehrlichia chaffeensis].	25.17	437	259	13	47	452	232	631	4e-15	88.2
rs:WP_016368965	DNA topoisomerase I, partial [Lactobacillus paracasei].	23.84	432	263	11	43	452	176	563	4e-15	88.2
rs:WP_034500488	DNA topoisomerase I [Actinomyces sp. S6-Spd3].	25.66	343	212	9	61	386	273	589	4e-15	88.6
rs:WP_008355071	DNA topoisomerase I [Nocardioidaceae bacterium Broad-1].	28.40	331	186	13	42	356	255	550	4e-15	88.6
rs:WP_028341022	DNA topoisomerase I [Bradyrhizobium elkanii].	25.18	425	255	12	61	454	244	636	4e-15	88.6
rs:WP_002776977	DNA topoisomerase I [Microcystis aeruginosa].	24.34	378	238	11	41	401	249	595	4e-15	88.6
rs:WP_029618624	DNA topoisomerase I [Rhizobium sp. MGL06].	25.62	441	261	14	47	452	230	638	4e-15	88.6
rs:WP_013837612	DNA topoisomerase I [Isoptericola variabilis].	27.64	351	196	12	35	356	241	562	4e-15	88.6
rs:WP_039229698	DNA topoisomerase I [Alteromonas macleodii].	27.34	384	207	13	8	377	239	564	4e-15	88.6
rs:WP_046902757	DNA topoisomerase I [Altererythrobacter atlanticus].	25.81	465	272	16	22	449	194	622	4e-15	88.6
rs:WP_047954201	DNA topoisomerase I, partial [Neisseria gonorrhoeae].	25.46	432	261	13	41	452	225	615	4e-15	88.2
rs:WP_004458499	DNA topoisomerase I [Clostridium perfringens].	25.23	432	252	17	47	454	224	608	4e-15	88.2
rs:WP_031390299	DNA topoisomerase I [Clostridium sp. KNHs209].	23.60	445	281	11	28	457	213	613	4e-15	88.2
tr:A0A0F0I132_ASPPA	SubName: Full=TopA {ECO:0000313|EMBL:KJK60357.1};	26.30	346	195	9	45	369	267	573	4e-15	88.2
rs:WP_035685089	DNA topoisomerase I [Avibacterium paragallinarum].	26.05	380	230	15	77	446	290	628	4e-15	88.6
rs:WP_018398472	DNA topoisomerase I [filamentous cyanobacterium ESFC-1].	27.52	298	184	7	77	370	285	554	4e-15	88.6
rs:WP_044124813	DNA topoisomerase I, partial [Prevotella loescheii].	33.16	196	121	5	232	425	12	199	4e-15	85.5
tr:H2CDW9_9LEPT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.62	451	299	11	18	451	234	651	4e-15	88.2
rs:WP_032118150	DNA topoisomerase I [Clostridium sp. CL-2].	23.06	425	270	10	47	454	224	608	4e-15	88.2
rs:WP_005706314	topoisomerase I [Haemophilus parahaemolyticus].	26.77	381	226	16	77	446	290	628	4e-15	88.2
rs:WP_047952514	DNA topoisomerase I, partial [Neisseria gonorrhoeae].	25.46	432	261	13	41	452	225	615	4e-15	88.2
rs:WP_035025623	MULTISPECIES: DNA topoisomerase I [Proteobacteria].	24.94	441	261	16	47	452	230	635	4e-15	88.2
rs:WP_022500236	DNA topoisomerase [Firmicutes bacterium CAG:95].	25.60	414	246	14	61	454	240	611	4e-15	88.2
rs:WP_002261844	hypothetical protein [Streptococcus mutans].	25.64	390	243	13	18	397	223	575	4e-15	87.8
rs:WP_025494540	DNA topoisomerase III, partial [Lachnospiraceae bacterium VE202-12].	29.30	215	146	5	40	252	232	442	4e-15	87.4
rs:WP_024269854	DNA topoisomerase III [Clostridium perfringens].	26.44	295	183	12	98	382	306	576	4e-15	88.2
rs:WP_003482634	DNA topoisomerase III [Clostridium perfringens].	26.91	327	204	13	66	382	275	576	4e-15	88.2
rs:WP_031773420	DNA topoisomerase I [Pseudomonas aeruginosa].	25.12	410	244	13	74	459	260	630	4e-15	88.2
rs:WP_044261765	DNA topoisomerase I [Campylobacter jejuni].	25.59	426	245	17	47	450	225	600	4e-15	88.2
rs:WP_005659512	topoisomerase I [Haemophilus influenzae].	25.39	382	230	15	77	446	290	628	4e-15	88.2
tr:W4S9F2_9XANT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.90	301	165	12	66	350	10	280	4e-15	87.8
rs:WP_022357103	DNA topoisomerase [Ruminococcus sp. CAG:379].	25.17	429	253	16	48	452	226	610	4e-15	88.2
rs:WP_043273977	DNA topoisomerase I [Pseudomonas sp. AAC].	23.49	430	271	13	50	459	235	626	4e-15	88.2
rs:WP_034220760	DNA topoisomerase I [Arenimonas donghaensis].	29.51	305	169	11	66	354	254	528	4e-15	88.2
rs:WP_027239369	DNA topoisomerase I [Pseudophaeobacter arcticus].	26.90	461	254	19	41	454	225	649	4e-15	88.2
rs:WP_030446875	DNA topoisomerase I [Actinocatenispora sera].	26.72	408	240	16	35	425	263	628	4e-15	88.2
rs:WP_022853525	DNA topoisomerase I [Thermodesulfatator atlanticus].	25.93	428	250	14	45	452	222	602	4e-15	88.2
rs:WP_022498137	DNA topoisomerase [Megasphaera elsdenii CAG:570].	24.63	471	275	17	18	452	240	666	4e-15	88.2
rs:WP_047938673	DNA topoisomerase I [Corynebacterium diphtheriae].	25.90	332	210	8	31	354	249	552	4e-15	88.6
rs:WP_003099575	DNA topoisomerase I [Streptococcus iniae].	23.15	406	248	11	65	452	266	625	4e-15	88.2
rs:WP_007082332	DNA topoisomerase I [Rhodanobacter fulvus].	27.65	358	208	13	45	380	233	561	4e-15	88.2
rs:WP_004864071	DNA topoisomerase I [Bartonella vinsonii].	26.41	443	253	17	47	452	230	636	4e-15	88.2
rs:WP_007555187	DNA topoisomerase I [Dialister micraerophilus].	26.81	429	250	19	47	454	254	639	4e-15	88.2
rs:WP_040216033	DNA topoisomerase I [Haemophilus parahaemolyticus].	26.77	381	226	16	77	446	290	628	4e-15	88.2
rs:WP_034605787	DNA topoisomerase I [Desulfovibrio desulfuricans].	25.43	409	230	17	66	452	242	597	4e-15	87.8
tr:L8UF82_AGGAC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.94	376	243	11	77	446	290	628	4e-15	88.2
rs:WP_024666109	DNA topoisomerase I [Pseudomonas syringae].	26.41	409	248	15	49	446	261	627	4e-15	88.2
rs:WP_027208859	DNA topoisomerase I [Butyrivibrio hungatei].	23.87	444	275	13	28	454	209	606	4e-15	88.2
rs:WP_033991699	DNA topoisomerase I [Pseudomonas aeruginosa].	24.38	402	257	11	74	459	260	630	4e-15	88.2
rs:WP_028449871	DNA topoisomerase I [Chitinibacter tainanensis].	24.94	433	260	13	43	452	228	618	4e-15	88.2
rs:WP_041326303	DNA topoisomerase I [Ruminococcus champanellensis].	25.17	429	253	16	48	452	241	625	4e-15	88.2
rs:WP_012085191	DNA topoisomerase I [Kineococcus radiotolerans].	27.45	368	213	12	42	387	267	602	4e-15	88.2
rs:WP_016368026	DNA topoisomerase I [Lactobacillus paracasei].	23.84	432	263	11	43	452	223	610	4e-15	88.2
rs:WP_005323095	DNA topoisomerase I [Corynebacterium pseudogenitalium].	25.21	361	214	11	47	384	266	593	4e-15	88.2
rs:WP_023955026	topoisomerase IA [Microbacterium sp. TS-1].	28.04	321	193	10	77	385	289	583	4e-15	88.2
rs:WP_034031775	DNA topoisomerase I [Pseudomonas aeruginosa].	25.06	411	243	14	74	459	260	630	4e-15	87.8
rs:WP_011104593	DNA topoisomerase I [Pseudomonas syringae group genomosp. 3].	26.41	409	248	15	49	446	261	627	4e-15	88.2
rs:WP_026493829	DNA topoisomerase I [Butyrivibrio sp. XPD2006].	23.64	423	268	13	48	454	223	606	4e-15	88.2
rs:WP_015207494	DNA topoisomerase I [Cylindrospermum stagnale].	24.44	446	268	14	28	446	225	628	4e-15	88.2
rs:WP_036503429	DNA topoisomerase I [Nitrosococcus oceani].	27.35	373	211	11	33	377	221	561	4e-15	88.2
rs:WP_048486681	DNA topoisomerase I, partial [Lactobacillus rhamnosus].	23.96	434	260	13	43	452	203	590	4e-15	88.2
rs:WP_038388563	DNA topoisomerase I [Bradyrhizobium elkanii].	25.18	425	255	12	61	454	244	636	4e-15	88.2
rs:WP_032133092	DNA topoisomerase I [Kingella kingae].	25.21	484	261	14	41	454	227	679	4e-15	88.2
rs:WP_024118930	DNA topoisomerase I [Thermus thermophilus].	26.35	406	224	15	69	454	272	622	4e-15	88.2
rs:WP_039743749	DNA topoisomerase I [Geobacter pickeringii].	24.22	483	262	16	43	457	227	673	4e-15	88.2
rs:WP_010216795	topoisomerase I [Pseudomonas syringae group genomosp. 3].	26.41	409	248	15	49	446	261	627	4e-15	88.2
rs:WP_009546432	MULTISPECIES: DNA topoisomerase I [Cyanothece].	25.90	417	243	16	40	436	241	611	4e-15	88.2
rs:WP_031331786	DNA topoisomerase I [Williamsia sp. D3].	24.93	365	225	10	41	387	266	599	4e-15	88.2
rs:WP_045680085	DNA topoisomerase I [Roseovarius sp. BRH_c41].	25.46	487	259	20	34	454	205	653	4e-15	88.2
rs:WP_022785614	DNA topoisomerase I [Clostridiales bacterium NK3B98].	25.63	437	246	15	48	454	229	616	4e-15	88.2
rs:WP_014309924	DNA topoisomerase I [Corynebacterium diphtheriae].	25.90	332	210	8	31	354	249	552	4e-15	88.2
rs:WP_002386831	DNA topoisomerase I, partial [Enterococcus faecalis].	25.00	364	219	14	34	377	211	540	4e-15	87.8
rs:WP_008278471	DNA topoisomerase I [Cyanothece sp. CCY0110].	23.52	438	263	13	23	436	213	602	4e-15	88.2
rs:XP_002139350	DNA topoisomerase family protein [Cryptosporidium muris RN66].	26.63	323	205	9	40	359	317	610	4e-15	88.2
rs:WP_040634296	DNA topoisomerase I [Mycobacterium phlei].	26.51	381	227	12	41	399	268	617	4e-15	88.2
rs:WP_022269185	DNA topoisomerase [Firmicutes bacterium CAG:424].	24.13	431	269	13	45	457	224	614	4e-15	88.2
tr:V5H6K9_IXORI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.25	408	243	13	6	394	266	630	4e-15	88.2
rs:WP_015535341	DNA topoisomerase I [Faecalitalea cylindroides].	23.98	442	260	14	40	455	219	610	4e-15	88.2
rs:WP_042462364	DNA topoisomerase I [Rhodovulum sulfidophilum].	24.89	474	254	16	47	452	231	670	4e-15	88.2
rs:WP_031755974	DNA topoisomerase I [Pseudomonas aeruginosa].	25.12	410	244	13	74	459	260	630	4e-15	87.8
rs:WP_046098886	DNA topoisomerase I [Avibacterium paragallinarum].	26.05	380	230	15	77	446	290	628	4e-15	88.2
rs:WP_044730147	DNA topoisomerase I [Mycoplasma hominis].	24.67	377	212	14	92	450	271	593	4e-15	87.8
rs:WP_019029394	topoisomerase I [Colwellia piezophila].	25.81	403	243	12	57	446	269	628	4e-15	88.2
rs:WP_019181621	DNA topoisomerase I [Microbacterium yannicii].	29.76	289	164	10	77	354	293	553	4e-15	88.2
rs:WP_024938530	DNA topoisomerase I [Xanthomonas arboricola].	28.53	382	206	16	66	413	254	602	4e-15	88.2
tr:A3ZX95_9PLAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.04	355	220	10	41	385	257	582	4e-15	88.2
rs:XP_012489371	PREDICTED: DNA topoisomerase 3-alpha isoform X4 [Gossypium raimondii].	24.44	450	258	14	39	451	264	668	4e-15	88.2
tr:I0RRM7_MYCPH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.51	381	227	12	41	399	255	604	4e-15	88.2
tr:T2MDP4_HYDVU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.82	415	249	12	60	452	66	439	4e-15	88.2
rs:WP_020313017	DNA topoisomerase I subunit omega [Pseudomonas syringae].	26.41	409	248	15	49	446	261	627	4e-15	88.2
rs:WP_037165268	MULTISPECIES: DNA topoisomerase I [Rhizobium].	25.62	441	261	14	47	452	230	638	4e-15	88.2
tr:V5GTF2_IXORI	SubName: Full=Putative dna topoisomerase iii alpha {ECO:0000313|EMBL:JAB73695.1}; Flags: Fragment;	23.88	423	276	12	27	434	249	640	4e-15	88.2
rs:WP_040163317	DNA topoisomerase I [Microbacterium sp. G3].	27.65	340	196	12	51	377	268	570	4e-15	88.2
rs:WP_020008659	DNA topoisomerase I [Salinicoccus albus].	23.92	393	243	14	77	452	253	606	4e-15	87.8
rs:WP_021999052	DNA topoisomerase [Acetobacter sp. CAG:977].	25.54	415	254	14	65	454	249	633	4e-15	88.2
rs:WP_024970798	DNA topoisomerase I [Microcystis aeruginosa].	24.34	378	238	11	41	401	249	595	4e-15	88.2
rs:WP_032963408	DNA topoisomerase I [Lactobacillus rhamnosus].	23.96	434	260	13	43	452	223	610	4e-15	87.8
tr:E6U7W7_ETHHY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.18	413	257	13	58	454	250	626	4e-15	87.8
rs:WP_026654728	DNA topoisomerase I [Butyrivibrio sp. AE3003].	24.10	444	274	14	28	454	209	606	4e-15	87.8
rs:WP_029651254	DNA topoisomerase I [Methylocystis sp. SB2].	26.63	413	228	15	77	452	260	634	4e-15	88.2
rs:WP_031285200	DNA topoisomerase I [Pseudomonas aeruginosa].	25.30	411	242	14	74	459	260	630	4e-15	87.8
tr:B1X1Z5_CYAA5	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.90	417	243	16	40	436	256	626	4e-15	88.2
rs:WP_021942988	DNA topoisomerase, partial [Clostridium sp. CAG:632].	26.61	372	217	12	102	457	5	336	4e-15	87.0
tr:B1BLL7_CLOPF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.44	295	183	12	98	382	306	576	4e-15	87.8
rs:WP_034172188	DNA topoisomerase I [Chrysanthemum yellows phytoplasma].	23.87	419	257	14	47	450	217	588	4e-15	87.8
rs:WP_015060283	DNA topoisomerase I [uncultured bacterium HHV35].	24.55	444	274	16	22	459	216	604	4e-15	88.2
rs:WP_037383320	DNA topoisomerase I [Sinorhizobium americanum].	24.89	438	268	13	47	452	230	638	4e-15	88.2
rs:WP_032124739	DNA topoisomerase I [Chlamydia sp. 'Diamant'].	23.89	427	266	13	47	454	240	626	4e-15	88.2
rs:WP_041686590	DNA topoisomerase I [Ethanoligenens harbinense].	25.18	413	257	13	58	454	260	636	4e-15	87.8
rs:WP_042260024	DNA topoisomerase III [Clostridium perfringens].	26.44	295	183	12	98	382	293	563	4e-15	87.8
rs:WP_046206438	DNA topoisomerase I [Streptococcus thermophilus].	24.45	409	238	14	65	452	270	628	4e-15	87.8
rs:WP_035058842	DNA topoisomerase I [Andreprevotia chitinilytica].	27.54	403	218	17	77	452	262	617	4e-15	88.2
rs:WP_021916891	DNA topoisomerase [Brachyspira sp. CAG:484].	24.87	390	237	12	77	450	279	628	4e-15	88.2
rs:WP_002750250	DNA topoisomerase I [Microcystis aeruginosa].	24.34	378	238	11	41	401	249	595	4e-15	88.2
rs:WP_022314822	DNA topoisomerase [Ruminococcus sp. CAG:382].	27.61	402	236	18	70	452	276	641	4e-15	88.2
rs:WP_004836449	DNA topoisomerase I [Anaerococcus tetradius].	22.73	462	283	13	18	452	187	601	4e-15	87.8
rs:WP_005544715	topoisomerase I [Aggregatibacter actinomycetemcomitans].	23.94	376	243	11	77	446	290	628	4e-15	88.2
rs:WP_005765057	MULTISPECIES: topoisomerase I [Pseudomonas syringae group].	26.41	409	248	15	49	446	261	627	4e-15	88.2
rs:WP_012877128	DNA topoisomerase I [Xylanimonas cellulosilytica].	27.83	406	223	14	35	404	239	610	4e-15	88.2
rs:WP_033573047	DNA topoisomerase I [Lactobacillus rhamnosus].	23.96	434	260	13	43	452	223	610	4e-15	87.8
rs:WP_009169157	DNA topoisomerase I [Clostridium sp. DL-VIII].	22.95	427	268	11	47	454	224	608	4e-15	87.8
rs:WP_040033789	DNA topoisomerase I [Haemophilus influenzae].	25.86	379	232	14	77	446	290	628	5e-15	88.2
rs:WP_019789876	hypothetical protein [Streptococcus sobrinus].	26.04	338	209	10	71	401	276	579	5e-15	87.8
rs:WP_035287277	DNA topoisomerase I [Actinokineospora sp. EG49].	27.35	351	204	12	47	378	272	590	5e-15	88.2
rs:WP_047393617	DNA topoisomerase I [Chitinibacter sp. ZOR0017].	25.12	426	254	13	50	452	235	618	5e-15	87.8
rs:WP_007017743	topoisomerase I [Bermanella marisrubri].	24.94	417	268	12	36	446	254	631	5e-15	88.2
rs:WP_039099413	DNA topoisomerase I [Lactobacillus curvatus].	25.22	448	244	18	41	452	219	611	5e-15	87.8
tr:L8TXQ7_AGGAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	23.94	376	243	11	77	446	101	439	5e-15	87.8
rs:WP_013015783	DNA topoisomerase I [Stackebrandtia nassauensis].	27.61	326	191	11	42	354	253	546	5e-15	88.2
rs:WP_046344689	DNA topoisomerase I [Xanthomonas campestris].	28.53	382	206	16	66	413	254	602	5e-15	88.2
rs:WP_034029993	DNA topoisomerase I [Pseudomonas aeruginosa].	25.06	411	243	14	74	459	260	630	5e-15	87.8
rs:WP_013666437	DNA topoisomerase I [Sphingobacterium sp. 21].	26.55	275	170	6	70	340	244	490	5e-15	87.8
gp:FP929058_741	DNA topoisomerase I [Enterococcus sp. 7L76]	25.00	364	219	14	34	377	211	540	5e-15	87.8
rs:WP_034686384	DNA topoisomerase I [Acinetobacter baumannii].	24.55	444	274	16	22	459	216	604	5e-15	87.8
rs:WP_026444414	DNA topoisomerase I [Acinetobacter sp. UNC436CL71CviS28].	24.55	444	274	16	22	459	216	604	5e-15	87.8
rs:WP_026348843	DNA topoisomerase I [Psychrobacter lutiphocae].	26.61	436	245	22	40	452	272	655	5e-15	88.2
rs:WP_042748214	DNA topoisomerase I [Lactococcus lactis].	22.85	407	248	12	65	452	263	622	5e-15	87.8
rs:WP_046412494	DNA topoisomerase I [Bacteroides sp. N54.MGS-20].	27.09	299	182	7	40	334	212	478	5e-15	87.8
tr:E6QVF7_9ZZZZ	SubName: Full=DNA topoisomerase 1 (DNA topoisomerase I) (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) {ECO:0000313|EMBL:CBI11230.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI11230.1};	27.04	429	249	18	45	454	232	615	5e-15	88.2
rs:WP_016902511	DNA topoisomerase I [Xanthomonas arboricola].	28.53	382	206	16	66	413	254	602	5e-15	88.2
rs:WP_016363891	DNA topoisomerase I, partial [Lactobacillus paracasei].	23.84	432	263	11	43	452	223	610	5e-15	87.8
tr:K1Z8A5_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	24.82	415	269	11	45	452	51	429	5e-15	87.4
rs:WP_005576194	topoisomerase I [Aggregatibacter actinomycetemcomitans].	23.67	376	244	11	77	446	290	628	5e-15	88.2
rs:WP_021359105	DNA topoisomerase I [Peptoclostridium difficile].	21.56	436	283	10	36	454	215	608	5e-15	87.8
rs:WP_043104942	DNA topoisomerase I [Xanthomonas arboricola].	28.53	382	206	16	66	413	254	602	5e-15	88.2
rs:WP_040486728	DNA topoisomerase I, partial [Idiomarina sp. A28L].	25.71	389	238	13	77	452	289	639	5e-15	88.2
rs:WP_013555570	DNA topoisomerase I [Deinococcus maricopensis].	27.07	362	221	10	35	387	240	567	5e-15	87.8
rs:WP_002821098	DNA topoisomerase I [Oenococcus oeni].	24.56	399	242	12	70	452	254	609	5e-15	87.8
rs:WP_002820441	DNA topoisomerase I [Oenococcus oeni].	24.56	399	242	12	70	452	254	609	5e-15	87.8
rs:XP_012245760	PREDICTED: DNA topoisomerase 3-alpha-like isoform X2 [Bombus impatiens].	24.94	437	268	14	39	452	206	605	5e-15	88.2
tr:A0A0F2J753_9BACT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJR43245.1};	24.94	433	262	15	47	454	241	635	5e-15	87.8
rs:WP_003003886	DNA topoisomerase I [Sphingobacterium spiritivorum].	26.88	279	172	6	60	334	233	483	5e-15	87.8
rs:WP_013245718	DNA topoisomerase I [Lactobacillus casei].	23.84	432	263	11	43	452	223	610	5e-15	87.8
rs:WP_047127472	DNA topoisomerase I [Xanthomonas arboricola].	28.53	382	206	16	66	413	254	602	5e-15	87.8
rs:WP_005856589	DNA topoisomerase I [Sagittula stellata].	26.55	467	253	19	41	454	225	654	5e-15	88.2
tr:V8D3C4_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.93	365	225	10	41	387	271	604	5e-15	88.2
rs:WP_002796370	DNA topoisomerase I [Microcystis aeruginosa].	24.34	378	238	11	41	401	249	595	5e-15	88.2
rs:WP_012616618	DNA topoisomerase I [Chloroflexus aggregans].	25.61	492	246	18	47	452	231	688	5e-15	87.8
rs:WP_024745936	DNA topoisomerase I [Xanthomonas oryzae].	28.53	382	206	16	66	413	254	602	5e-15	87.8
rs:WP_022669886	DNA topoisomerase I [Hippea alviniae].	22.97	444	282	12	25	454	206	603	5e-15	87.8
rs:WP_009218704	DNA topoisomerase I [Lachnospiraceae oral taxon 107].	23.87	444	275	13	34	457	214	614	5e-15	87.8
rs:WP_033125859	DNA topoisomerase I [Eubacterium sp. ER2].	23.29	425	274	10	48	457	227	614	5e-15	87.8
rs:XP_011652135	PREDICTED: DNA topoisomerase 3-alpha [Cucumis sativus].	24.50	449	265	15	37	452	264	671	5e-15	88.2
rs:WP_034957424	DNA topoisomerase I [Erythrobacter longus].	24.85	495	286	18	1	452	173	624	5e-15	88.2
rs:WP_007988003	MULTISPECIES: DNA topoisomerase I [Paraglaciecola].	25.00	436	252	15	31	446	250	630	5e-15	88.2
rs:WP_013110457	DNA topoisomerase I [Planctopirus limnophila].	26.63	383	232	13	36	402	250	599	5e-15	88.2
rs:WP_039203318	DNA topoisomerase I [Aphanizomenon flos-aquae].	24.73	376	241	10	41	402	249	596	5e-15	88.2
rs:WP_025298389	DNA topoisomerase I [Aggregatibacter actinomycetemcomitans].	23.94	376	243	11	77	446	290	628	5e-15	88.2
rs:WP_015205082	DNA topoisomerase I [Crinalium epipsammum].	26.82	384	234	12	40	406	248	601	5e-15	88.2
rs:WP_039036869	DNA topoisomerase I [Pseudoalteromonas sp. ECSMB14103].	27.25	345	202	13	66	395	280	590	5e-15	88.2
rs:WP_013753682	topoisomerase I [Glaciecola sp. 4H-3-7+YE-5].	25.00	436	252	15	31	446	250	630	5e-15	88.2
rs:WP_044420078	DNA topoisomerase I [Pseudomonas syringae group genomosp. 3].	26.41	409	248	15	49	446	261	627	5e-15	87.8
tr:V8CQI8_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETD29285.1};	36.13	155	96	3	232	384	41	194	5e-15	85.5
rs:XP_012489370	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Gossypium raimondii].	24.44	450	258	14	39	451	264	668	5e-15	88.2
rs:WP_014892639	DNA topoisomerase I [Methylocystis sp. SC2].	26.94	412	228	16	77	452	260	634	5e-15	88.2
rs:WP_004415122	DNA topoisomerase I [Mycoplasma arginini].	25.13	378	207	13	92	449	271	592	5e-15	87.8
rs:WP_016830088	DNA topoisomerase I [Corynebacterium diphtheriae].	25.90	332	210	8	31	354	249	552	5e-15	88.2
rs:WP_014318578	DNA topoisomerase I [Corynebacterium diphtheriae].	25.90	332	210	8	31	354	249	552	5e-15	88.2
rs:WP_045136213	DNA topoisomerase I [Lactobacillus paracasei].	23.84	432	263	11	43	452	223	610	5e-15	87.8
tr:A8SJ74_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.64	414	243	14	66	457	252	618	5e-15	87.8
rs:WP_014976305	topoisomerase I [Alteromonas macleodii].	26.07	422	246	17	43	446	257	630	5e-15	87.8
rs:WP_044038350	DNA topoisomerase I [Clostridium bornimense].	23.80	395	242	11	77	452	257	611	5e-15	87.8
rs:WP_005688022	DNA topoisomerase I [Lactobacillus rhamnosus].	23.96	434	260	13	43	452	223	610	5e-15	87.8
rs:WP_010488381	MULTISPECIES: DNA topoisomerase I [Lactobacillus casei group].	23.96	434	260	13	43	452	223	610	5e-15	87.8
rs:WP_027276830	DNA topoisomerase I [Rhodopseudomonas palustris].	26.53	441	262	13	45	454	228	637	5e-15	88.2
rs:WP_039027048	DNA topoisomerase I [Pseudomonas aeruginosa].	25.06	411	243	14	74	459	260	630	5e-15	87.8
rs:WP_014065398	topoisomerase I [Haemophilus parainfluenzae].	25.66	378	234	14	77	446	290	628	5e-15	87.8
rs:WP_025254952	DNA topoisomerase I [Alteromonas sp. ALT199].	26.04	457	255	18	8	446	239	630	5e-15	87.8
rs:WP_018463724	DNA topoisomerase I [Prevotella paludivivens].	28.08	260	156	6	77	334	252	482	5e-15	87.8
tr:A0A0D9MNM3_ASPFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.28	331	188	8	45	358	267	558	5e-15	87.8
rs:WP_042923545	DNA topoisomerase I [Kingella kingae].	25.93	486	255	16	41	454	227	679	5e-15	87.8
rs:WP_043087498	DNA topoisomerase I [Xanthomonas arboricola].	28.53	382	206	16	66	413	254	602	5e-15	87.8
rs:WP_023104007	DNA topoisomerase I [Pseudomonas aeruginosa].	25.06	411	243	14	74	459	260	630	5e-15	87.8
rs:WP_024334496	DNA topoisomerase I [Desulfotignum balticum].	24.88	426	258	13	47	452	225	608	5e-15	87.8
tr:S6V5Y6_PSESF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.41	409	248	15	49	446	218	584	5e-15	87.8
rs:WP_019995290	DNA topoisomerase I [Aureimonas ureilytica].	26.48	423	232	16	70	449	253	639	5e-15	87.8
rs:WP_027353472	DNA topoisomerase I [Desulfosarcina sp. BuS5].	23.73	434	269	14	40	452	218	610	5e-15	87.8
rs:XP_001025000	DNA topoisomerase I [Tetrahymena thermophila SB210].	25.29	344	204	12	56	385	519	823	5e-15	88.2
rs:WP_040596886	DNA topoisomerase I [Parvimonas micra].	24.64	414	243	14	66	457	246	612	5e-15	87.8
rs:WP_039815909	DNA topoisomerase I [Xanthomonas arboricola].	28.53	382	206	16	66	413	254	602	5e-15	87.8
rs:WP_026722768	DNA topoisomerase I [Fischerella sp. PCC 9431].	24.24	425	260	15	40	443	241	624	5e-15	87.8
rs:WP_032807188	DNA topoisomerase I [Oenococcus oeni].	24.56	399	242	11	70	452	254	609	5e-15	87.8
tr:A4NYH0_HAEIF	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.27	376	238	12	77	446	290	628	5e-15	87.8
rs:WP_038318343	DNA topoisomerase I [Kingella kingae].	25.21	484	261	14	41	454	227	679	5e-15	87.8
rs:WP_005715619	DNA topoisomerase I [Lactobacillus rhamnosus].	23.96	434	260	13	43	452	223	610	5e-15	87.8
rs:WP_005738758	MULTISPECIES: topoisomerase I [Pseudomonas syringae group].	26.41	409	248	15	49	446	261	627	5e-15	87.8
rs:WP_003081026	DNA topoisomerase I [Streptococcus macacae].	23.62	398	242	12	72	452	267	619	5e-15	87.8
rs:WP_010557475	topoisomerase I [Pseudoalteromonas marina].	27.25	345	202	13	66	395	280	590	5e-15	87.8
rs:WP_040352784	DNA topoisomerase I, partial [Blastopirellula marina].	27.04	355	220	10	41	385	247	572	5e-15	87.8
rs:WP_006792157	topoisomerase I [Alteromonadales bacterium TW-7].	27.25	345	202	13	66	395	280	590	5e-15	87.8
rs:WP_007692049	MULTISPECIES: DNA topoisomerase I [Rhizobium/Agrobacterium group].	25.90	444	257	15	47	452	230	639	5e-15	87.8
rs:WP_011472692	DNA topoisomerase I [Rhodopseudomonas palustris].	27.09	443	257	14	45	454	228	637	5e-15	87.8
rs:WP_032822705	DNA topoisomerase I [Oenococcus oeni].	24.56	399	242	12	70	452	254	609	5e-15	87.8
rs:WP_039638996	DNA topoisomerase I [Lactobacillus sp. FMNP02].	23.96	434	260	13	43	452	223	610	5e-15	87.8
rs:WP_013525788	topoisomerase I [Haemophilus influenzae].	25.86	379	232	14	77	446	290	628	5e-15	87.8
rs:WP_021035179	DNA topoisomerase I [Haemophilus influenzae].	25.86	379	232	14	77	446	290	628	5e-15	87.8
rs:XP_012489368	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Gossypium raimondii].	24.44	450	258	14	39	451	264	668	5e-15	87.8
rs:WP_037220614	DNA topoisomerase I [Rhizobium sp. YR060].	25.90	444	257	15	47	452	230	639	5e-15	87.8
rs:WP_043153070	DNA topoisomerase I [Pseudomonas aeruginosa].	24.82	411	244	14	74	459	260	630	5e-15	87.4
tr:B1BR51_CLOPF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.35	277	178	10	74	345	286	541	5e-15	87.8
rs:WP_011962037	topoisomerase I [Haemophilus influenzae].	25.86	379	232	14	77	446	290	628	5e-15	87.8
rs:WP_014186866	DNA topoisomerase I [Desulfosporosinus orientis].	25.41	425	263	13	48	454	225	613	5e-15	87.8
tr:B9JDL6_AGRRK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.90	444	257	15	47	452	231	640	5e-15	87.8
rs:WP_018953624	DNA topoisomerase I [Thioalkalivibrio sulfidiphilus].	27.33	322	188	10	44	350	232	522	5e-15	87.8
rs:XP_012489369	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Gossypium raimondii].	24.44	450	258	14	39	451	264	668	5e-15	87.8
rs:WP_026316472	DNA topoisomerase I [Actinokineospora enzanensis].	26.94	360	206	12	41	378	270	594	5e-15	87.8
rs:WP_048418634	DNA topoisomerase I [Mycobacterium chubuense].	27.85	395	231	13	38	410	265	627	5e-15	87.8
rs:WP_005414607	DNA topoisomerase I [Stenotrophomonas maltophilia].	29.57	301	166	12	66	350	254	524	5e-15	87.8
rs:WP_041035495	DNA topoisomerase I [Tolypothrix campylonemoides].	24.35	382	234	10	41	398	252	602	5e-15	87.8
rs:WP_005411198	DNA topoisomerase I [Stenotrophomonas maltophilia].	29.57	301	166	12	66	350	254	524	5e-15	87.8
rs:WP_008131540	topoisomerase I [Pseudoalteromonas sp. BSi20480].	27.25	345	202	13	66	395	280	590	5e-15	87.8
rs:WP_009003194	MULTISPECIES: DNA topoisomerase I [Clostridiales].	23.76	425	272	9	48	457	227	614	5e-15	87.8
rs:WP_046483688	DNA topoisomerase I [Oceanospirillaceae bacterium ASP10-02a].	25.51	439	252	19	37	452	255	641	5e-15	87.8
rs:WP_005327151	DNA topoisomerase I [Corynebacterium tuberculostearicum].	25.48	361	213	12	47	384	266	593	5e-15	87.8
rs:WP_030169091	MULTISPECIES: DNA topoisomerase I [Actinobacteria].	24.93	365	225	10	41	387	266	599	5e-15	87.8
tr:A7V8S5_BACUN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.83	309	179	9	40	340	226	498	5e-15	87.8
rs:XP_008605361	hypothetical protein SDRG_01605 [Saprolegnia diclina VS20].	26.53	377	225	12	39	399	261	601	5e-15	87.8
rs:WP_034525921	DNA topoisomerase I [Bacteroides uniformis].	27.83	309	179	9	40	340	216	488	5e-15	87.8
rs:WP_020744912	DNA topoisomerase I subunit omega [Alteromonas macleodii].	25.96	416	254	16	43	446	257	630	5e-15	87.8
rs:WP_012481370	DNA topoisomerase I [Stenotrophomonas maltophilia].	29.57	301	166	12	66	350	254	524	5e-15	87.8
rs:WP_019187748	DNA topoisomerase I [Candidatus Prevotella conceptionensis].	27.79	331	197	11	30	351	207	504	5e-15	87.8
rs:WP_016272395	DNA topoisomerase I [Bacteroides uniformis].	27.83	309	179	9	40	340	216	488	5e-15	87.8
rs:WP_041716195	DNA topoisomerase III, partial [Alicycliphilus denitrificans].	36.54	104	66	0	61	164	267	370	5e-15	86.3
rs:WP_043034573	DNA topoisomerase I [Stenotrophomonas maltophilia].	29.57	301	166	12	66	350	254	524	5e-15	87.8
rs:WP_012150651	DNA topoisomerase I [Rickettsia rickettsii].	25.30	415	243	16	65	449	250	627	5e-15	87.8
rs:WP_040940167	hypothetical protein, partial [Prochloron didemni].	26.60	312	190	8	77	379	294	575	5e-15	87.8
rs:WP_040012585	DNA topoisomerase, partial [Peptostreptococcaceae bacterium CM5].	31.20	250	148	9	40	286	230	458	5e-15	87.0
rs:WP_003565415	MULTISPECIES: DNA topoisomerase I [Lactobacillus casei group].	23.84	432	263	11	43	452	223	610	5e-15	87.8
rs:WP_019660785	DNA topoisomerase I [Stenotrophomonas maltophilia].	29.57	301	166	12	66	350	254	524	6e-15	87.8
rs:WP_040030611	DNA topoisomerase I [Staphylococcus cohnii].	23.38	432	269	16	40	452	217	605	6e-15	87.4
rs:WP_016868573	DNA topoisomerase I [Fischerella muscicola].	26.25	320	197	8	77	387	291	580	6e-15	87.8
rs:WP_037449541	DNA topoisomerase I, partial [Sinorhizobium fredii].	25.00	440	265	14	47	452	4	412	6e-15	87.4
rs:WP_034518694	DNA topoisomerase I [Agrobacterium rhizogenes].	25.90	444	257	15	47	452	230	639	6e-15	87.8
rs:WP_007294258	DNA topoisomerase I [delta proteobacterium MLMS-1].	24.74	477	291	15	7	452	192	631	6e-15	87.8
rs:XP_004323500	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-beta-1-like [Tursiops truncatus].	23.49	332	203	9	40	360	251	542	6e-15	87.4
rs:WP_031275716	DNA topoisomerase I [Pseudomonas aeruginosa].	24.88	410	245	13	74	459	260	630	6e-15	87.4
rs:WP_018271983	DNA topoisomerase I [Bradyrhizobium elkanii].	25.18	425	255	12	61	454	244	636	6e-15	87.8
rs:WP_013638549	DNA topoisomerase I [Desulfurobacterium thermolithotrophum].	24.88	434	247	16	43	450	225	605	6e-15	87.8
rs:XP_002978156	hypothetical protein SELMODRAFT_233065 [Selaginella moellendorffii].	24.20	438	267	15	35	454	260	650	6e-15	87.8
rs:WP_043013020	DNA topoisomerase III [Clostridium perfringens].	26.35	277	178	10	74	345	287	542	6e-15	87.8
tr:F7RUZ0_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.71	389	238	13	77	452	289	639	6e-15	87.8
rs:WP_002791753	DNA topoisomerase I [Microcystis aeruginosa].	24.34	378	238	11	41	401	249	595	6e-15	87.8
rs:WP_015449009	MULTISPECIES: DNA topoisomerase I [Rhodanobacter].	27.93	358	207	13	45	380	233	561	6e-15	87.8
rs:WP_016843950	DNA topoisomerase I, partial [Bradyrhizobium elkanii].	25.18	425	255	12	61	454	244	636	6e-15	87.8
rs:WP_046355048	DNA topoisomerase I [Pseudoalteromonas luteoviolacea].	25.12	414	252	16	48	446	261	631	6e-15	87.8
tr:A0A077C4A4_9RICK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.34	417	235	17	65	449	249	629	6e-15	87.8
rs:WP_003602230	DNA topoisomerase I [Lactobacillus casei].	23.84	432	263	11	43	452	223	610	6e-15	87.4
rs:WP_003925181	DNA topoisomerase I [Mycobacterium thermoresistibile].	26.51	381	227	12	41	399	268	617	6e-15	87.8
rs:WP_019300052	DNA topoisomerase I [Xanthomonas oryzae].	28.53	382	206	16	66	413	254	602	6e-15	87.8
rs:WP_017274264	DNA topoisomerase I [Sinorhizobium meliloti].	24.16	447	274	14	40	452	218	633	6e-15	87.8
rs:WP_024947298	DNA topoisomerase I [Pseudomonas aeruginosa].	24.13	402	258	11	74	459	260	630	6e-15	87.4
rs:XP_002864876	hypothetical protein ARALYDRAFT_496584 [Arabidopsis lyrata subsp. lyrata].	24.21	475	274	15	18	451	243	672	6e-15	87.8
rs:WP_000513586	DNA topoisomerase I subunit omega [Salmonella enterica].	26.91	379	228	14	77	446	284	622	6e-15	87.8
rs:WP_028470945	DNA topoisomerase I [Neptunomonas japonica].	25.00	420	262	15	45	452	263	641	6e-15	87.8
rs:WP_045625031	DNA topoisomerase I [Lactobacillus paracasei].	23.84	432	263	11	43	452	223	610	6e-15	87.4
rs:WP_021203233	DNA topoisomerase I [Stenotrophomonas maltophilia].	29.57	301	166	12	66	350	254	524	6e-15	87.8
rs:WP_048468710	DNA topoisomerase I [Mycobacterium chlorophenolicum].	27.85	395	231	13	38	410	265	627	6e-15	87.8
rs:WP_036762982	DNA topoisomerase I [Peptostreptococcus sp. MV1].	23.81	441	271	11	34	454	211	606	6e-15	87.4
rs:WP_034773800	DNA topoisomerase I [Idiomarina salinarum].	25.87	433	262	15	43	458	256	646	6e-15	87.8
rs:WP_011174282	DNA topoisomerase I [Thermus thermophilus].	25.85	414	232	15	61	454	264	622	6e-15	87.8
rs:WP_039524995	DNA topoisomerase I [Xanthomonas arboricola].	28.53	382	206	16	66	413	254	602	6e-15	87.8
rs:WP_031533810	MULTISPECIES: DNA topoisomerase I [Bacteroides].	27.65	264	151	8	77	334	250	479	6e-15	87.8
tr:A0A0A8VYF7_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.05	311	188	12	49	344	252	535	6e-15	87.4
rs:WP_008005249	DNA topoisomerase I [Halorubrum lipolyticum].	25.49	459	259	18	40	454	251	670	6e-15	87.8
rs:WP_011731723	DNA topoisomerase I [Campylobacter fetus].	24.17	422	256	14	47	450	224	599	6e-15	87.4
rs:WP_005687215	topoisomerase I [Haemophilus influenzae].	25.59	379	233	14	77	446	290	628	6e-15	87.8
rs:WP_046474260	DNA topoisomerase I [marine gamma proteobacterium ASP10-03a].	26.10	387	236	12	77	452	302	649	6e-15	87.8
rs:WP_014010951	DNA topoisomerase I [Corynebacterium variabile].	25.99	327	201	9	41	354	269	567	6e-15	87.8
rs:WP_016385941	DNA topoisomerase I [Lactobacillus paracasei].	23.84	432	263	11	43	452	223	610	6e-15	87.4
rs:WP_014038639	DNA topoisomerase I [Stenotrophomonas maltophilia].	29.57	301	166	12	66	350	254	524	6e-15	87.8
rs:WP_032129673	DNA topoisomerase I [Stenotrophomonas maltophilia].	29.57	301	166	12	66	350	254	524	6e-15	87.8
rs:WP_014949190	topoisomerase I [Alteromonas macleodii].	27.34	384	207	13	8	377	239	564	6e-15	87.8
rs:WP_024098242	DNA topoisomerase I [Phaeobacter gallaeciensis].	26.29	464	251	21	41	454	225	647	6e-15	87.8
rs:WP_028595587	DNA topoisomerase I [Paenibacillus assamensis].	23.34	467	292	13	18	457	187	614	6e-15	87.4
rs:WP_019304179	DNA topoisomerase I [Xanthomonas oryzae].	28.53	382	206	16	66	413	254	602	6e-15	87.8
rs:WP_038141185	DNA topoisomerase I [Thiothrix lacustris].	26.68	401	227	15	31	404	221	581	6e-15	87.8
rs:WP_027110232	DNA topoisomerase I [Lachnospiraceae bacterium NC2008].	24.25	400	243	12	74	454	253	611	6e-15	87.4
rs:WP_040616878	hypothetical protein, partial [Roseibium sp. TrichSKD4].	39.39	132	77	1	257	385	26	157	6e-15	84.7
rs:WP_030253943	DNA topoisomerase I [Streptacidiphilus jeojiense].	27.13	317	183	12	77	377	303	587	6e-15	87.8
rs:WP_022355826	DNA topoisomerase I [Firmicutes bacterium CAG:308].	23.98	442	260	14	40	455	10	401	6e-15	87.0
rs:WP_008662589	DNA topoisomerase I [Bacteroides sp. 4_1_36].	27.83	309	179	9	40	340	216	488	6e-15	87.8
tr:U7QC71_9CYAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.94	401	239	12	25	398	201	570	6e-15	87.8
rs:XP_012671463	PREDICTED: DNA topoisomerase 3-beta-1 [Clupea harengus].	22.99	422	254	13	40	434	263	640	6e-15	87.8
rs:WP_008862920	DNA topoisomerase I [Barnesiella intestinihominis].	27.09	299	182	7	40	334	212	478	6e-15	87.8
rs:WP_014364595	DNA topoisomerase I [Rickettsia philipii].	25.30	415	243	16	65	449	250	627	6e-15	87.8
tr:G9XCL0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.20	250	148	9	40	286	230	458	6e-15	87.0
rs:WP_028336381	DNA topoisomerase I [Bradyrhizobium elkanii].	25.18	425	255	12	61	454	244	636	6e-15	87.8
rs:WP_014016473	DNA topoisomerase I [Megasphaera elsdenii].	24.63	471	275	17	18	452	240	666	6e-15	87.4
rs:WP_006511007	DNA topoisomerase I [Xenococcus sp. PCC 7305].	25.21	365	231	9	41	396	249	580	6e-15	87.8
rs:WP_011366282	DNA topoisomerase I [Desulfovibrio alaskensis].	24.11	423	261	11	47	452	225	604	6e-15	87.4
tr:A0A072CGV2_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.89	438	268	13	47	452	225	633	6e-15	87.8
tr:A0A0F4LT78_9LACO	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJY61815.1};	23.13	428	267	13	44	452	236	620	6e-15	87.4
rs:WP_019338924	DNA topoisomerase I [Stenotrophomonas maltophilia].	29.57	301	166	12	66	350	254	524	6e-15	87.8
rs:WP_017534610	DNA topoisomerase I [Nocardiopsis alba].	25.63	359	217	11	36	377	271	596	6e-15	87.8
rs:WP_005834437	MULTISPECIES: DNA topoisomerase I [Bacteroides].	27.83	309	179	9	40	340	216	488	6e-15	87.8
rs:XP_001441837	hypothetical protein [Paramecium tetraurelia strain d4-2].	24.78	347	223	9	37	378	259	572	6e-15	87.8
tr:R9PPJ5_AGAAL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	412	263	13	42	446	217	589	6e-15	87.8
rs:WP_044467650	DNA topoisomerase I [Bacteroides uniformis].	27.83	309	179	9	40	340	216	488	6e-15	87.8
tr:K7T463_9NEIS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.53	294	175	8	50	331	234	498	6e-15	87.0
rs:WP_028459321	DNA topoisomerase I [Chloroflexus sp. Y-396-1].	27.89	355	206	11	47	378	231	558	6e-15	87.4
rs:WP_010535667	DNA topoisomerase I [Bacteroides faecis].	27.07	314	182	10	36	334	201	482	6e-15	87.4
tr:A0A098E8V4_9ZZZZ	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:CEG12462.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEG12462.1};	26.62	278	159	10	189	452	1	247	6e-15	85.1
rs:WP_005023339	topoisomerase I [Shigella dysenteriae].	26.06	376	235	12	77	446	284	622	6e-15	87.8
tr:U5HC52_USTV1	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDE04881.1, ECO:0000313|EnsemblFungi:MVLG_04740T0};	25.36	351	215	10	39	377	261	576	6e-15	87.8
rs:WP_035487194	hypothetical protein, partial [Geminicoccus roseus].	27.25	444	259	15	41	452	225	636	6e-15	87.8
rs:WP_034051068	DNA topoisomerase I [Pseudomonas aeruginosa].	24.94	405	251	13	74	459	260	630	6e-15	87.4
rs:WP_038380389	DNA topoisomerase I [Bradyrhizobium elkanii].	25.18	425	255	12	61	454	244	636	6e-15	87.8
rs:WP_037460195	DNA topoisomerase I, partial [Sinorhizobium fredii].	25.00	440	265	14	47	452	13	421	6e-15	87.4
rs:WP_042601494	DNA topoisomerase I [Haemophilus influenzae].	25.59	379	233	14	77	446	290	628	6e-15	87.8
tr:S6PVT2_PSESF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	26.41	409	248	15	49	446	133	499	6e-15	87.4
rs:WP_038315269	DNA topoisomerase I [Kingella kingae].	25.21	484	261	14	41	454	227	679	6e-15	87.4
rs:WP_042404870	DNA topoisomerase I [Streptacidiphilus carbonis].	27.13	317	183	12	77	377	307	591	6e-15	87.8
rs:XP_007526280	PREDICTED: DNA topoisomerase 3-alpha [Erinaceus europaeus].	25.25	400	233	13	77	450	302	661	6e-15	87.8
rs:WP_042282227	DNA topoisomerase I [Nocardiopsis sp. TP-A0876].	25.63	359	217	11	36	377	271	596	6e-15	87.8
rs:WP_040488363	DNA topoisomerase I, partial [Fodinicurvata sediminis].	25.24	420	249	17	65	452	250	636	6e-15	87.8
rs:WP_007156365	DNA topoisomerase I [Oribacterium sinus].	24.94	397	243	13	74	454	253	610	6e-15	87.4
tr:A4N5H6_HAEIF	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.33	379	234	14	77	446	290	628	6e-15	87.8
rs:WP_029221354	DNA topoisomerase I [Xanthomonas cassavae].	28.80	382	205	16	66	413	254	602	6e-15	87.4
rs:WP_024846942	DNA topoisomerase I [Aminobacter sp. J41].	25.47	428	251	16	60	452	241	635	6e-15	87.8
rs:XP_005391750	PREDICTED: DNA topoisomerase 3-beta-1 isoform X5 [Chinchilla lanigera].	23.58	441	255	17	40	453	263	648	6e-15	87.8
rs:WP_040421020	DNA topoisomerase I [Corynebacterium timonense].	26.76	340	195	12	30	354	243	543	6e-15	87.8
rs:WP_011961921	topoisomerase I [Haemophilus influenzae].	25.59	379	233	14	77	446	290	628	6e-15	87.8
rs:WP_029416389	DNA topoisomerase I [Brevundimonas bacteroides].	26.30	441	262	17	43	452	225	633	6e-15	87.8
rs:WP_037526447	DNA topoisomerase I, partial [Sphingobacterium sp. IITKGP-BTPF85].	30.65	199	118	6	46	234	247	435	6e-15	86.7
rs:WP_002800297	DNA topoisomerase I [Microcystis aeruginosa].	24.34	378	238	11	41	401	249	595	6e-15	87.8
rs:XP_012245759	PREDICTED: DNA topoisomerase 3-alpha-like isoform X1 [Bombus impatiens].	24.94	437	268	14	39	452	290	689	6e-15	87.8
rs:WP_024658808	DNA topoisomerase I [Pseudomonas syringae].	26.41	409	248	15	49	446	261	627	6e-15	87.8
rs:WP_013376622	DNA topoisomerase I [Stigmatella aurantiaca].	24.17	451	264	13	41	452	284	695	6e-15	87.4
rs:WP_022236962	DNA topoisomerase [Clostridium leptum CAG:27].	25.32	462	248	16	47	449	225	648	6e-15	87.4
rs:WP_042614482	DNA topoisomerase I [Stenotrophomonas maltophilia].	30.03	303	162	11	66	350	254	524	6e-15	87.4
tr:X0V631_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_S08955 {ECO:0000313|EMBL:GAG13649.1}; Flags: Fragment;	29.66	263	151	5	166	415	20	261	6e-15	84.3
rs:WP_035147818	DNA topoisomerase I [Campylobacter fetus].	24.17	422	256	14	47	450	224	599	6e-15	87.4
rs:WP_018581804	DNA topoisomerase I [Corynebacterium pilosum].	27.08	325	191	11	41	354	263	552	6e-15	87.8
rs:XP_005107460	PREDICTED: DNA topoisomerase 3-beta-1-like [Aplysia californica].	23.74	417	257	13	40	434	260	637	6e-15	87.4
rs:WP_027727258	DNA topoisomerase I [Treponema sp. C6A8].	23.60	428	261	15	46	452	233	615	7e-15	87.4
rs:WP_013527698	topoisomerase I [Haemophilus influenzae].	25.86	379	232	14	77	446	290	628	7e-15	87.4
rs:WP_041651541	DNA topoisomerase I [Anaplasma centrale].	25.23	440	254	15	47	452	232	630	7e-15	87.4
rs:WP_012623949	DNA topoisomerase I [Desulfovibrio desulfuricans].	24.33	411	261	10	54	452	232	604	7e-15	87.4
tr:E6VVS8_DESAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.36	431	248	15	45	450	228	605	7e-15	87.4
rs:WP_007970275	DNA topoisomerase I [Xanthomonas fuscans].	28.50	379	210	16	66	413	254	602	7e-15	87.4
rs:WP_018163831	DNA topoisomerase I [Streptococcus henryi].	22.62	442	269	13	34	452	230	621	7e-15	87.4
rs:WP_004763747	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	26.79	321	195	10	40	356	267	551	7e-15	87.4
rs:WP_013629763	DNA topoisomerase I [Rubinisphaera brasiliensis].	25.63	355	217	10	47	386	263	585	7e-15	87.4
rs:WP_008267195	DNA topoisomerase I [Stenotrophomonas sp. SKA14].	29.57	301	166	12	66	350	254	524	7e-15	87.4
rs:WP_029220880	DNA topoisomerase I [Xanthomonas cassavae].	25.23	428	264	14	46	459	229	614	7e-15	87.4
rs:XP_002966408	hypothetical protein SELMODRAFT_168492 [Selaginella moellendorffii].	24.20	438	267	15	35	454	235	625	7e-15	87.4
rs:WP_022234894	DNA topoisomerase [Eubacterium sp. CAG:202].	25.54	466	244	18	42	449	228	648	7e-15	87.4
rs:WP_036656511	DNA topoisomerase I [Paenibacillus wynnii].	23.96	434	258	16	50	457	227	614	7e-15	87.4
rs:WP_011378684	DNA topoisomerase I [Shigella dysenteriae].	26.06	376	235	12	77	446	284	622	7e-15	87.4
tr:D1AS91_ANACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.23	440	254	15	47	452	233	631	7e-15	87.4
rs:WP_031887220	DNA topoisomerase III, partial [Staphylococcus aureus].	29.90	204	132	7	255	454	9	205	7e-15	84.3
rs:WP_024734480	DNA topoisomerase I [Clostridiales bacterium VE202-15].	24.24	425	269	11	48	457	233	619	7e-15	87.4
rs:WP_021596265	DNA topoisomerase I [Actinomadura madurae].	26.22	328	192	11	77	387	283	577	7e-15	87.4
rs:WP_029014305	DNA topoisomerase I [Niveispirillum irakense].	25.16	461	253	15	41	454	225	640	7e-15	87.4
rs:WP_036204645	DNA topoisomerase I [Megasphaera elsdenii].	24.63	471	275	17	18	452	240	666	7e-15	87.4
rs:WP_040458502	hypothetical protein, partial [Holospora obtusa].	25.87	433	267	13	41	449	226	628	7e-15	87.4
rs:WP_033082724	DNA topoisomerase I [Colwellia psychrerythraea].	25.75	400	247	12	57	446	269	628	7e-15	87.4
tr:A0A0D6L2I0_9CYAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.14	329	200	10	77	395	256	551	7e-15	87.4
rs:WP_032823063	DNA topoisomerase I, partial [Haemophilus influenzae].	25.33	379	234	14	77	446	290	628	7e-15	87.4
rs:WP_021907930	DNA topoisomerase [Eubacterium sp. CAG:146].	23.78	429	263	13	47	454	226	611	7e-15	87.4
rs:WP_037663076	DNA topoisomerase I [Streptomyces griseofuscus].	26.61	342	195	12	35	354	250	557	7e-15	87.4
tr:A0A090NCS4_SHIDY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.06	376	235	12	77	446	298	636	7e-15	87.4
tr:K6AC25_9PORP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.29	369	234	11	40	384	237	591	7e-15	87.4
rs:WP_008949746	topoisomerase I [Alishewanella jeotgali].	25.71	319	199	8	42	356	245	529	7e-15	87.4
rs:WP_014908638	DNA topoisomerase I [Nocardiopsis alba].	25.63	359	217	11	36	377	271	596	7e-15	87.4
tr:S2UTZ2_LACPA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.84	432	263	11	43	452	131	518	7e-15	87.0
rs:WP_007513531	DNA topoisomerase I [Rhodanobacter denitrificans].	27.93	358	207	13	45	380	233	561	7e-15	87.4
rs:WP_038452680	DNA topoisomerase I [Campylobacter fetus].	24.17	422	256	14	47	450	224	599	7e-15	87.4
rs:WP_009459295	MULTISPECIES: DNA topoisomerase I [Fischerella].	26.60	312	190	8	77	379	291	572	7e-15	87.4
rs:WP_027242705	DNA topoisomerase I [Piscirickettsia salmonis].	25.85	414	245	14	61	452	248	621	7e-15	87.4
tr:X7RXE5_FUSNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.07	339	215	13	60	385	251	563	7e-15	87.4
rs:WP_022118872	DNA topoisomerase [Firmicutes bacterium CAG:56].	24.08	461	283	16	18	457	200	614	7e-15	87.4
rs:WP_027182567	DNA topoisomerase I [Desulfovibrio alaskensis].	24.11	423	261	11	47	452	225	604	7e-15	87.4
rs:WP_032585425	DNA topoisomerase I [Bacteroides fragilis].	25.33	383	244	12	21	391	220	572	7e-15	87.0
rs:WP_047628692	DNA topoisomerase I [Rhizobium tropici].	25.90	444	256	16	47	452	230	638	7e-15	87.4
rs:WP_027247922	DNA topoisomerase I [Phaeobacter inhibens].	26.02	465	251	20	41	454	225	647	7e-15	87.4
rs:WP_004270304	DNA topoisomerase I [Lactobacillus curvatus].	25.22	448	244	18	41	452	219	611	7e-15	87.4
rs:WP_025643987	MULTISPECIES: DNA topoisomerase I [Psychrobacter].	26.23	366	210	13	36	384	306	628	7e-15	87.4
rs:WP_010474526	DNA topoisomerase I [Acaryochloris sp. CCMEE 5410].	26.22	347	215	9	41	377	249	564	7e-15	87.4
rs:WP_040943789	DNA topoisomerase I [Prochloron didemni].	26.60	312	190	8	77	379	294	575	7e-15	87.4
rs:WP_028000105	DNA topoisomerase I [Sinorhizobium arboris].	24.66	438	269	13	47	452	230	638	7e-15	87.4
rs:XP_010703264	DNA topoisomerase III, putative [Leishmania panamensis].	26.58	365	217	11	31	379	238	567	7e-15	87.4
rs:WP_012855440	DNA topoisomerase I [Mycoplasma hominis].	24.14	377	214	13	92	450	271	593	7e-15	87.0
rs:WP_029950317	DNA topoisomerase I [Parvimonas micra].	24.64	414	243	14	66	457	246	612	7e-15	87.4
rs:WP_029967608	DNA topoisomerase I [Desulfonauticus sp. A7A].	23.06	477	298	15	1	452	170	602	7e-15	87.4
rs:WP_019459946	MULTISPECIES: DNA topoisomerase I [Roseomonas].	25.71	424	259	14	60	454	244	640	7e-15	87.4
rs:WP_040843384	DNA topoisomerase I [Nitrospirillum amazonense].	26.13	444	256	16	47	454	233	640	7e-15	87.4
rs:WP_009016940	DNA topoisomerase I [Parabacteroides sp. D13].	26.29	369	234	11	40	384	213	567	7e-15	87.4
rs:WP_022141914	DNA topoisomerase [Clostridium sp. CAG:230].	24.61	451	269	16	28	457	213	613	7e-15	87.4
rs:WP_008436951	DNA topoisomerase I [Rhodanobacter thiooxydans].	27.93	358	207	13	45	380	233	561	7e-15	87.4
rs:WP_015778211	DNA topoisomerase I [Anaerococcus prevotii].	22.22	459	289	14	18	452	187	601	7e-15	87.0
rs:WP_041271527	DNA topoisomerase I, partial [Desulfovibrio aespoeensis].	24.36	431	248	15	45	450	228	605	7e-15	87.4
rs:WP_046316504	DNA topoisomerase I [Lactobacillus mellifer].	23.13	428	267	13	44	452	244	628	7e-15	87.4
rs:WP_023082041	DNA topoisomerase I [Pseudomonas aeruginosa].	24.82	411	244	13	74	459	260	630	7e-15	87.0
rs:XP_007137778	hypothetical protein PHAVU_009G154800g [Phaseolus vulgaris].	23.48	443	277	13	39	454	260	667	7e-15	87.0
rs:WP_004321457	DNA topoisomerase I [Campylobacter showae].	25.59	422	250	15	47	450	224	599	7e-15	87.4
rs:WP_014794888	MULTISPECIES: DNA topoisomerase I [Desulfitobacterium].	26.65	409	245	15	66	457	244	614	7e-15	87.0
rs:XP_010674423	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Beta vulgaris subsp. vulgaris].	24.67	450	259	15	39	452	265	670	7e-15	87.4
rs:WP_033993318	DNA topoisomerase I [Pseudomonas aeruginosa].	25.06	411	243	14	74	459	260	630	7e-15	87.0
tr:Q31J81_THICR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.36	296	168	9	47	335	223	478	7e-15	87.4
rs:WP_046219671	DNA topoisomerase I [Photobacterium halotolerans].	25.71	420	254	15	40	446	253	627	7e-15	87.4
rs:WP_032890733	DNA topoisomerase [Fusobacterium nucleatum].	25.07	339	215	13	60	385	255	567	8e-15	87.0
rs:WP_044345697	DNA topoisomerase I [Haemophilus influenzae].	25.72	381	230	14	77	446	290	628	8e-15	87.4
rs:WP_003533084	DNA topoisomerase I [[Clostridium] leptum].	25.32	462	248	16	47	449	225	648	8e-15	87.0
rs:WP_042930287	DNA topoisomerase I [Pseudomonas aeruginosa].	24.82	411	244	13	74	459	260	630	8e-15	87.0
rs:WP_023101907	DNA topoisomerase I [Pseudomonas aeruginosa].	24.82	411	244	13	74	459	260	630	8e-15	87.0
rs:WP_016437384	DNA topoisomerase 1 [Streptomyces sp. HGB0020].	26.61	342	195	12	35	354	250	557	8e-15	87.4
rs:WP_042068216	DNA topoisomerase I ['Chrysanthemum coronarium' phytoplasma].	23.87	419	257	14	47	450	217	588	8e-15	87.0
rs:WP_006990851	DNA topoisomerase I [Paraglaciecola mesophila].	25.77	423	248	18	42	446	256	630	8e-15	87.4
rs:WP_044562983	DNA topoisomerase I [Azospirillum sp. B4].	25.68	444	258	15	47	454	233	640	8e-15	87.4
rs:WP_037559452	DNA topoisomerase I [Spirillospora albida].	25.00	368	217	13	37	379	257	590	8e-15	87.4
tr:A0A086J4E5_9MICR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.10	364	228	13	39	397	249	576	8e-15	87.4
rs:WP_026217997	DNA topoisomerase I [Streptomyces scabrisporus].	27.05	329	193	11	42	354	265	562	8e-15	87.4
rs:WP_023094336	DNA topoisomerase I [Pseudomonas aeruginosa].	24.94	405	251	13	74	459	260	630	8e-15	87.0
rs:WP_005002702	DNA topoisomerase I [Nitrococcus mobilis].	26.19	378	226	12	61	416	248	594	8e-15	87.4
tr:W4PSY6_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE22941.1};	33.53	170	102	4	154	323	30	188	8e-15	83.6
rs:WP_038247321	DNA topoisomerase I [Zetaproteobacteria bacterium TAG-1].	23.83	428	278	11	41	454	227	620	8e-15	87.4
rs:WP_005957513	DNA topoisomerase III [Fusobacterium necrophorum].	23.57	403	252	11	60	444	262	626	8e-15	87.4
tr:X1PTH7_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S12043 {ECO:0000313|EMBL:GAI42405.1}; Flags: Fragment;	30.58	291	151	11	77	358	13	261	8e-15	84.3
rs:WP_043597838	DNA topoisomerase I [Aeromonas diversa].	26.59	361	219	10	35	384	245	570	8e-15	87.4
rs:WP_012720956	DNA topoisomerase I [Clostridium botulinum].	24.13	431	237	15	74	449	252	647	8e-15	87.0
rs:WP_008772731	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	26.29	369	234	11	40	384	213	567	8e-15	87.4
rs:WP_009797455	DNA topoisomerase I [Nitrobacter sp. Nb-311A].	24.94	441	268	13	45	454	228	636	8e-15	87.4
rs:XP_006746431	PREDICTED: DNA topoisomerase 3-beta-1-like [Leptonychotes weddellii].	24.62	394	218	15	86	453	48	388	8e-15	87.0
rs:WP_033945040	DNA topoisomerase I [Pseudomonas aeruginosa].	25.06	411	243	13	74	459	260	630	8e-15	87.0
rs:XP_010674422	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Beta vulgaris subsp. vulgaris].	24.67	450	259	15	39	452	265	670	8e-15	87.4
rs:WP_013386983	DNA topoisomerase I [Ilyobacter polytropus].	25.00	384	225	14	18	377	188	532	8e-15	87.4
rs:WP_036617743	DNA topoisomerase I [Parabacteroides distasonis].	26.29	369	234	11	40	384	213	567	8e-15	87.4
rs:WP_040484655	DNA topoisomerase I [Lyngbya aestuarii].	25.94	401	239	12	25	398	230	599	8e-15	87.4
rs:XP_008443146	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Cucumis melo].	24.78	452	260	16	37	452	264	671	8e-15	87.4
rs:WP_029504183	DNA topoisomerase I [Lachnoclostridium phytofermentans].	23.22	422	272	11	48	454	227	611	8e-15	87.0
rs:WP_012455374	DNA topoisomerase I [Methylobacterium populi].	27.23	448	239	18	43	452	236	634	8e-15	87.4
rs:WP_043831062	DNA topoisomerase I [Roseomonas aerilata].	26.39	360	213	11	41	379	227	555	8e-15	87.4
rs:WP_012056085	DNA topoisomerase I [Parabacteroides distasonis].	26.29	369	234	11	40	384	213	567	8e-15	87.4
rs:WP_017196441	DNA topoisomerase I [Bartonella birtlesii].	26.28	430	244	16	61	453	244	637	8e-15	87.4
rs:WP_018195577	hypothetical protein [Candidatus Fervidibacter sacchari].	24.05	449	265	14	47	458	280	689	8e-15	87.4
rs:WP_007788928	DNA topoisomerase I [Peptostreptococcus stomatis].	23.53	425	265	10	47	454	225	606	8e-15	87.0
rs:WP_043079487	DNA topoisomerase I [Mycobacterium immunogenum].	26.91	379	228	11	41	399	252	601	8e-15	87.4
rs:XP_009995964	PREDICTED: DNA topoisomerase 3-beta-1 [Chaetura pelagica].	23.46	422	252	14	40	434	263	640	8e-15	87.4
tr:A0A078TF53_9PORP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.29	369	234	11	40	384	206	560	8e-15	87.4
rs:WP_038312059	DNA topoisomerase I [Kingella kingae].	25.00	484	262	14	41	454	227	679	8e-15	87.0
tr:G1XWN3_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.13	444	256	16	47	454	226	633	8e-15	87.4
rs:WP_038151015	DNA topoisomerase I [Veillonella montpellierensis].	22.22	441	271	11	38	454	284	676	8e-15	87.0
rs:WP_010968273	DNA topoisomerase III [Clostridium perfringens].	26.10	295	184	12	98	382	306	576	8e-15	87.0
rs:WP_015432594	DNA topoisomerase 1 [Bibersteinia trehalosi].	25.71	350	215	9	18	356	225	540	8e-15	87.4
rs:WP_036819223	DNA topoisomerase I, partial [Piscirickettsia salmonis].	25.85	414	245	14	61	452	248	621	8e-15	87.0
rs:WP_023110980	DNA topoisomerase I [Pseudomonas aeruginosa].	24.82	411	244	13	74	459	260	630	8e-15	87.0
rs:WP_010001831	DNA topoisomerase I [Leuconostoc lactis].	23.99	421	237	17	61	452	267	633	8e-15	87.0
rs:WP_046735689	DNA topoisomerase I [Xanthomonas axonopodis].	25.23	428	264	14	46	459	229	614	8e-15	87.0
rs:WP_046932464	DNA topoisomerase I [Xanthomonas perforans].	25.23	428	264	14	46	459	229	614	8e-15	87.0
rs:WP_047676743	DNA topoisomerase I [Lactobacillus rhamnosus].	23.96	434	260	13	43	452	223	610	8e-15	87.0
rs:WP_019468457	MULTISPECIES: DNA topoisomerase I [Staphylococcus].	22.69	432	272	15	40	452	217	605	8e-15	87.0
rs:WP_040134388	DNA topoisomerase I [Azospirillum brasilense].	26.93	479	272	16	16	454	203	643	8e-15	87.4
rs:WP_035784394	DNA topoisomerase I [Clostridium botulinum].	24.10	415	250	14	61	454	238	608	8e-15	87.0
gp:HF952106_1036	DNA topoisomerase I [Streptococcus agalactiae ILRI112]	23.37	398	243	12	72	452	12	364	8e-15	86.3
rs:WP_034086288	DNA topoisomerase I [Pseudomonas aeruginosa].	25.06	411	243	13	74	459	260	630	8e-15	87.0
rs:WP_011010569	DNA topoisomerase I [Clostridium perfringens].	24.88	430	256	16	47	454	224	608	8e-15	87.0
rs:WP_013244953	DNA topoisomerase I [Brachyspira pilosicoli].	22.77	426	266	14	47	452	236	618	8e-15	87.0
rs:WP_045867561	DNA topoisomerase I [Tolypothrix sp. PCC 7601].	26.14	329	200	10	77	395	285	580	8e-15	87.4
rs:WP_030749301	DNA topoisomerase I [Streptomyces griseus].	26.79	336	196	12	35	354	256	557	8e-15	87.4
rs:WP_034820062	DNA topoisomerase I [Idiomarina sp. 28-8].	27.25	378	229	15	77	446	290	629	8e-15	87.4
rs:WP_004462358	DNA topoisomerase I [[Clostridium] symbiosum].	24.59	427	265	14	48	457	230	616	8e-15	87.0
tr:H2YRK8_CIOSA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.29	350	220	9	39	378	313	627	8e-15	87.0
rs:WP_002443101	topoisomerase I [Shimwellia blattae].	26.77	381	226	15	77	446	287	625	8e-15	87.4
tr:D4RFQ4_ENTFC	SubName: Full=Topoisomerase {ECO:0000313|EMBL:EFF27246.1};	25.51	247	173	3	193	437	3	240	8e-15	85.1
rs:WP_005837859	DNA topoisomerase I [Eubacterium saphenum].	25.42	421	242	15	60	457	244	615	8e-15	87.0
rs:XP_001272941	DNA topoisomerase III, putative [Aspergillus clavatus NRRL 1].	26.49	336	190	9	41	358	262	558	9e-15	87.0
rs:WP_036341814	DNA topoisomerase I [Mycobacterium aromaticivorans].	26.25	381	228	11	41	399	273	622	9e-15	87.4
rs:WP_022972837	DNA topoisomerase I, partial [Xanthomonas sp. M97].	27.85	395	218	16	53	413	241	602	9e-15	87.0
rs:WP_033963406	DNA topoisomerase I [Pseudomonas aeruginosa].	25.37	410	243	13	74	459	260	630	9e-15	87.0
rs:WP_035513040	DNA topoisomerase, partial [Lactobacillus iners].	28.40	243	160	6	159	398	28	259	9e-15	84.0
rs:WP_008828828	MULTISPECIES: DNA topoisomerase I [Sphingomonadaceae].	27.52	407	234	18	69	452	251	619	9e-15	87.4
rs:WP_003502432	DNA topoisomerase I [Agrobacterium tumefaciens].	25.96	443	257	16	47	452	230	638	9e-15	87.4
rs:WP_013908188	DNA topoisomerase I [Thermodesulfatator indicus].	25.64	429	246	15	47	452	224	602	9e-15	87.0
rs:WP_035791091	DNA topoisomerase I [Clostridium botulinum].	24.10	415	250	14	61	454	238	608	9e-15	87.0
rs:WP_031684974	DNA topoisomerase I [Pseudomonas aeruginosa].	24.82	411	244	14	74	459	260	630	9e-15	87.0
rs:WP_028498669	DNA topoisomerase I [Microvirgula aerodenitrificans].	26.20	439	246	15	43	452	227	616	9e-15	87.0
rs:WP_048446736	DNA topoisomerase I [Methylobacterium variabile].	26.58	444	247	15	43	452	236	634	9e-15	87.4
rs:WP_012695386	DNA topoisomerase [Lactobacillus brevis].	25.79	411	255	15	60	455	266	641	9e-15	87.0
rs:WP_019173403	DNA topoisomerase I [Pseudaminobacter salicylatoxidans].	25.97	439	263	15	45	452	228	635	9e-15	87.0
tr:D9PJ37_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EFK96429.1}; Flags: Fragment;	28.91	211	111	4	206	399	5	193	9e-15	83.2
rs:WP_003001121	DNA topoisomerase I [Sphingobacterium spiritivorum].	26.88	279	172	6	60	334	233	483	9e-15	87.0
tr:U4TQT7_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.46	422	262	10	55	457	228	607	9e-15	87.0
rs:WP_033398064	DNA topoisomerase I [Fusobacterium russii].	25.93	324	180	12	74	377	249	532	9e-15	87.0
rs:WP_005693995	DNA topoisomerase I [Haemophilus influenzae].	25.59	379	233	14	77	446	290	628	9e-15	87.0
rs:WP_013669135	DNA topoisomerase I [Aerococcus urinae].	23.81	441	260	18	38	452	220	610	9e-15	87.0
rs:WP_016268924	DNA topoisomerase I [Bacteroides thetaiotaomicron].	25.95	316	183	9	36	334	201	482	9e-15	87.0
rs:WP_012816676	DNA topoisomerase III, partial [Staphylococcus aureus].	32.07	184	115	6	275	454	3	180	9e-15	83.6
rs:WP_023408496	hypothetical protein [uncultured Desulfofustis sp. PB-SRB1].	35.19	162	93	4	40	195	261	416	9e-15	86.3
rs:WP_033746803	DNA topoisomerase I [Pantoea sp. NGS-ED-1003].	26.60	391	231	15	77	452	284	633	9e-15	87.0
rs:WP_011919438	topoisomerase I [Shewanella putrefaciens].	25.24	424	263	15	35	446	250	631	9e-15	87.0
rs:WP_037063478	DNA topoisomerase I [Rhizobium leguminosarum].	25.51	439	264	14	47	452	230	638	9e-15	87.0
rs:WP_040172041	DNA topoisomerase I [Phaeobacter sp. S26].	26.29	464	251	21	41	454	225	647	9e-15	87.0
tr:E5X107_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.95	316	183	8	36	334	211	492	9e-15	87.0
rs:WP_046104204	DNA topoisomerase I [Devosia chinhatensis].	27.67	430	255	14	47	452	230	627	9e-15	87.0
rs:WP_044119047	DNA topoisomerase III, partial [Staphylococcus aureus].	31.15	183	118	5	275	454	7	184	9e-15	83.6
rs:WP_018226243	DNA topoisomerase I [actinobacterium SCGC AAA028-A23].	26.76	370	220	12	41	390	248	586	9e-15	87.0
rs:WP_040534196	DNA topoisomerase I [Lactobacillus shenzhenensis].	23.46	422	262	10	55	457	233	612	9e-15	87.0
rs:WP_008220403	topoisomerase I [Rheinheimera nanhaiensis].	26.69	341	201	11	62	386	258	565	9e-15	87.0
rs:WP_023119716	DNA topoisomerase I [Pseudomonas aeruginosa].	24.57	411	245	13	74	459	260	630	9e-15	87.0
rs:WP_006589617	DNA topoisomerase I [Bartonella birtlesii].	26.28	430	244	16	61	453	244	637	9e-15	87.0
rs:WP_014956947	DNA topoisomerase I [Desulfobacula toluolica].	24.89	438	266	15	36	452	214	609	9e-15	87.0
rs:WP_035207854	DNA topoisomerase I [Agrobacterium tumefaciens].	25.57	442	260	15	47	452	230	638	9e-15	87.0
rs:WP_018718076	DNA topoisomerase I [Arhodomonas aquaeolei].	28.65	370	204	14	31	377	221	553	9e-15	87.0
rs:WP_018193230	MULTISPECIES: hypothetical protein [unclassified Thaumarchaeota (miscellaneous)].	24.55	391	241	12	60	439	253	600	9e-15	86.7
rs:WP_012424370	DNA topoisomerase I [Clostridium botulinum].	24.10	415	250	14	61	454	238	608	9e-15	87.0
tr:W6TE90_HOLOB	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.87	433	267	13	41	449	226	628	9e-15	87.0
tr:E7FNV6_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.06	425	243	16	57	452	255	624	9e-15	87.0
rs:WP_022451857	DNA topoisomerase [Clostridium sp. CAG:269].	23.76	425	267	12	47	454	226	610	9e-15	87.0
tr:A0A073I4G1_9PORP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.29	369	234	11	40	384	250	604	9e-15	87.0
rs:WP_033066679	hypothetical protein [Clostridium botulinum].	24.42	385	238	13	77	446	282	628	9e-15	87.0
rs:WP_025289380	DNA topoisomerase I [Bibersteinia trehalosi].	25.71	350	215	9	18	356	225	540	9e-15	87.0
rs:XP_008443143	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Cucumis melo].	24.78	452	260	16	37	452	264	671	9e-15	87.0
rs:WP_018265474	DNA topoisomerase I [Methylosinus sp. LW4].	25.70	428	247	14	60	452	243	634	9e-15	87.0
rs:XP_008443145	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Cucumis melo].	24.78	452	260	16	37	452	264	671	9e-15	87.0
rs:WP_046661409	DNA topoisomerase I [Microcystis aeruginosa].	24.34	378	238	11	41	401	249	595	9e-15	87.0
rs:WP_039123365	DNA topoisomerase I [Lactobacillus ruminis].	23.29	425	242	16	57	452	228	597	9e-15	87.0
rs:WP_022105370	DNA topoisomerase [Dialister sp. CAG:486].	23.36	428	264	13	48	454	254	638	9e-15	87.0
rs:WP_027437844	DNA topoisomerase I [Lachnospira multipara].	23.26	430	274	12	45	457	224	614	9e-15	87.0
rs:WP_017261889	DNA topoisomerase I [Lactobacillus rossiae].	24.26	408	242	16	65	452	257	617	9e-15	87.0
rs:WP_030334236	DNA topoisomerase I [Micromonospora parva].	25.75	365	217	13	42	386	261	591	9e-15	87.0
rs:WP_003370835	DNA topoisomerase I [Clostridium botulinum].	23.54	429	263	14	47	454	224	608	9e-15	87.0
rs:WP_002583384	DNA topoisomerase I [[Clostridium] clostridioforme].	23.71	426	270	12	48	457	233	619	9e-15	87.0
rs:WP_038248833	DNA topoisomerase I [Wolbachia endosymbiont of Glossina morsitans morsitans].	25.11	442	253	15	47	452	231	630	9e-15	87.0
rs:WP_037136048	DNA topoisomerase I [Rhizobium leucaenae].	26.13	444	256	15	47	452	230	639	9e-15	87.0
rs:WP_008840962	DNA topoisomerase I [Pediococcus lolii].	25.06	415	239	17	61	452	242	607	9e-15	87.0
rs:WP_011200271	topoisomerase I [[Mannheimia] succiniciproducens].	25.96	416	239	16	45	446	268	628	9e-15	87.0
rs:WP_044390317	DNA topoisomerase I [Pseudomonas syringae group genomosp. 3].	26.16	409	249	15	49	446	261	627	9e-15	87.0
rs:WP_026464733	DNA topoisomerase I [Adhaeribacter aquaticus].	26.40	322	196	9	21	334	190	478	9e-15	87.0
rs:WP_010237231	DNA topoisomerase I [Citromicrobium bathyomarinum].	27.11	439	255	16	41	452	224	624	9e-15	87.0
rs:XP_007490460	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Monodelphis domestica].	22.70	467	277	18	18	453	237	650	9e-15	87.0
rs:WP_029249170	DNA topoisomerase I [Mycobacterium avium].	27.37	358	210	11	38	377	265	590	9e-15	87.0
tr:T1B7U3_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EQD50280.1}; Flags: Fragment;	26.28	274	162	9	188	453	15	256	9e-15	86.3
rs:WP_011667572	DNA topoisomerase I [Lactobacillus brevis].	25.06	439	260	15	41	457	234	625	9e-15	87.0
rs:WP_005619258	DNA topoisomerase I [Pseudomonas avellanae].	26.63	413	242	16	49	446	261	627	1e-14	87.0
rs:WP_021651815	DNA topoisomerase I [Blautia sp. KLE 1732].	25.06	439	270	14	34	454	212	609	1e-14	87.0
rs:WP_032880430	DNA topoisomerase [Fusobacterium nucleatum].	24.50	449	288	17	24	452	211	628	1e-14	87.0
rs:WP_011234261	topoisomerase I [Idiomarina loihiensis].	27.25	378	229	15	77	446	290	629	1e-14	87.0
rs:WP_001625658	DNA topoisomerase I [Escherichia coli].	25.80	376	236	11	77	446	284	622	1e-14	87.0
rs:WP_020310043	MULTISPECIES: DNA topoisomerase [Megasphaera].	24.63	471	275	17	18	452	240	666	1e-14	87.0
rs:WP_006907650	DNA topoisomerase I [Facklamia hominis].	24.88	406	240	14	66	452	244	603	1e-14	87.0
rs:WP_035107281	DNA topoisomerase I [Corynebacterium camporealensis].	25.34	371	221	13	41	389	255	591	1e-14	87.0
rs:WP_014979097	topoisomerase I [Alteromonas macleodii].	25.82	457	256	18	8	446	239	630	1e-14	87.0
rs:WP_034716810	DNA topoisomerase I [Bacteroides eggerthii].	25.95	316	183	8	36	334	201	482	1e-14	87.0
rs:WP_013115817	DNA topoisomerase I [Cellulomonas flavigena].	27.13	387	229	12	41	404	252	608	1e-14	87.0
rs:WP_017826122	DNA topoisomerase I [Clostridium botulinum].	23.54	429	263	14	47	454	224	608	1e-14	87.0
rs:WP_003698300	DNA topoisomerase I [Lactobacillus ruminis].	23.06	425	243	16	57	452	228	597	1e-14	86.7
tr:N4WV55_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00085286};	25.00	388	231	14	90	457	1	348	1e-14	85.9
tr:A0A098EFI4_ANAPH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.52	431	250	16	54	452	239	630	1e-14	87.0
sp:TOP1_HAEIN	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.59	379	233	14	77	446	290	628	1e-14	87.0
tr:A0A0D6AJC9_9CHRO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.19	393	238	10	47	413	255	617	1e-14	87.0
rs:WP_022653837	DNA topoisomerase I [Aquaspirillum serpens].	25.57	481	256	17	45	459	233	677	1e-14	87.0
rs:WP_043387664	MULTISPECIES: DNA topoisomerase I [Methylobacterium].	26.46	446	245	17	43	452	236	634	1e-14	87.0
rs:WP_001482712	DNA topoisomerase I [Escherichia coli].	25.80	376	236	11	77	446	284	622	1e-14	87.0
rs:WP_035945202	DNA topoisomerase I [Fusobacterium perfoetens].	26.22	431	255	18	40	452	219	604	1e-14	87.0
tr:W7YM17_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.78	343	217	9	4	335	180	492	1e-14	87.0
rs:WP_001678703	DNA topoisomerase I [Escherichia coli].	25.80	376	236	11	77	446	284	622	1e-14	87.0
rs:XP_002424239	DNA topoisomerase 3-beta, putative [Pediculus humanus corporis].	24.79	363	235	11	40	396	262	592	1e-14	87.0
rs:WP_036258330	DNA topoisomerase I, partial [Mesorhizobium sp. WSM3224].	26.00	450	257	19	41	452	224	635	1e-14	87.0
rs:WP_016647809	DNA topoisomerase I [Facklamia hominis].	24.88	406	240	14	66	452	244	603	1e-14	86.7
rs:XP_010144869	PREDICTED: DNA topoisomerase 3-beta-1 [Eurypyga helias].	24.20	438	260	15	25	434	247	640	1e-14	87.0
rs:WP_002762074	DNA topoisomerase I [Microcystis aeruginosa].	24.34	378	238	11	41	401	249	595	1e-14	87.0
rs:WP_046148222	DNA topoisomerase I [Parabacteroides sp. HGS0025].	25.41	370	238	11	40	384	213	569	1e-14	87.0
rs:WP_045255925	DNA topoisomerase I [Microbacterium hydrocarbonoxydans].	29.81	322	173	13	51	356	252	536	1e-14	87.0
tr:A0A0E9F0H0_CHLTH	SubName: Full=DNA topoisomerase I-fused to SWI domain {ECO:0000313|EMBL:CRH75050.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRH75050.1};	26.55	275	163	7	182	452	87	326	1e-14	85.9
rs:WP_026763856	DNA topoisomerase I [Sediminibacterium salmoneum].	27.12	306	189	8	39	342	217	490	1e-14	87.0
rs:WP_045384234	DNA topoisomerase I [Mycobacterium kyorinense].	26.05	380	229	11	41	399	268	616	1e-14	87.0
rs:WP_025759091	DNA topoisomerase I [Shigella flexneri].	26.33	376	234	12	77	446	284	622	1e-14	87.0
rs:WP_039874304	DNA topoisomerase I [Paenibacillus sp. FSL R7-0273].	24.42	434	256	16	50	457	227	614	1e-14	86.7
rs:WP_005955940	DNA topoisomerase I [Peptoniphilus harei].	22.82	425	268	13	47	454	228	609	1e-14	86.7
rs:WP_006986741	DNA topoisomerase I [Cardiobacterium valvarum].	28.65	342	207	10	43	377	232	543	1e-14	87.0
rs:WP_022207783	DNA topoisomerase [Eubacterium sp. CAG:252].	23.10	420	256	11	60	457	239	613	1e-14	86.7
tr:W7VGT4_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.52	388	232	14	42	409	302	652	1e-14	87.0
rs:WP_007592026	DNA topoisomerase I [Lachnoanaerobaculum sp. OBRC5-5].	23.92	439	282	12	34	457	214	615	1e-14	86.7
rs:WP_001497537	DNA topoisomerase I [Escherichia coli].	25.80	376	236	11	77	446	284	622	1e-14	87.0
rs:WP_027341883	DNA topoisomerase I [Hamadaea tsunoensis].	26.48	389	224	14	42	409	253	600	1e-14	87.0
rs:WP_009612532	DNA topoisomerase I [actinobacterium SCGC AAA027-L06].	26.76	370	220	12	41	390	248	586	1e-14	87.0
rs:XP_007497919	PREDICTED: DNA topoisomerase 3-alpha [Monodelphis domestica].	24.04	445	271	15	40	456	272	677	1e-14	87.0
rs:WP_019225611	MULTISPECIES: DNA topoisomerase I [Dehalobacter].	24.61	447	246	15	60	449	237	649	1e-14	86.7
rs:WP_031556695	DNA topoisomerase I [Lachnospira multipara].	23.26	430	274	12	45	457	224	614	1e-14	86.7
rs:WP_046923200	DNA topoisomerase I [Lactobacillus ruminis].	23.06	425	243	16	57	452	255	624	1e-14	86.7
rs:XP_011176901	PREDICTED: DNA topoisomerase 3-beta [Bactrocera cucurbitae].	24.16	356	229	11	37	385	256	577	1e-14	87.0
rs:WP_027473323	DNA topoisomerase I [Saccharicrinis fermentans].	24.78	343	217	9	4	335	180	492	1e-14	87.0
rs:WP_011450708	DNA topoisomerase I [Anaplasma phagocytophilum].	25.52	431	250	16	54	452	239	630	1e-14	87.0
rs:WP_006243846	DNA topoisomerase I [Mycobacterium tusciae].	26.18	382	227	12	41	399	268	617	1e-14	87.0
rs:WP_013445935	DNA topoisomerase I [Paludibacter propionicigenes].	27.11	273	163	7	65	334	242	481	1e-14	87.0
rs:WP_006718223	DNA topoisomerase I [Desulfitobacterium metallireducens].	27.14	409	246	12	65	457	243	615	1e-14	86.7
rs:WP_042041488	DNA topoisomerase I [Aeromonas rivuli].	24.82	427	263	14	42	452	252	636	1e-14	87.0
tr:A0A0A1WJC1_BACCU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.16	356	229	11	37	385	256	577	1e-14	87.0
rs:WP_041429665	DNA topoisomerase I, partial [Synechococcus sp. PCC 7502].	26.06	376	222	13	41	395	249	589	1e-14	87.0
rs:WP_028729778	DNA topoisomerase I [Parabacteroides gordonii].	25.41	370	238	11	40	384	213	569	1e-14	86.7
rs:WP_027482820	DNA topoisomerase I [Deinococcus pimensis].	27.47	364	227	11	31	387	233	566	1e-14	86.7
rs:WP_038335130	DNA topoisomerase I [Kingella kingae].	25.41	484	260	15	41	454	227	679	1e-14	86.7
rs:WP_023398362	DNA topoisomerase I [Pseudoalteromonas luteoviolacea].	24.94	417	249	15	48	446	261	631	1e-14	87.0
rs:WP_024499534	DNA topoisomerase I [Gordonia amicalis].	25.84	356	215	11	41	378	265	589	1e-14	87.0
rs:WP_012329483	DNA topoisomerase I [Methylobacterium radiotolerans].	25.79	411	243	15	65	459	250	614	1e-14	86.7
rs:WP_005072605	DNA topoisomerase I [Mycobacterium abscessus].	26.65	379	229	11	41	399	258	607	1e-14	87.0
rs:WP_022092241	DNA topoisomerase I [Firmicutes bacterium CAG:536].	26.29	407	219	14	75	452	253	607	1e-14	86.7
rs:WP_010189916	DNA topoisomerase I [Corynebacterium aurimucosum].	25.75	365	214	13	41	384	253	581	1e-14	87.0
rs:WP_017291142	hypothetical protein [Leptolyngbya boryana].	26.13	375	217	13	40	399	236	565	1e-14	86.7
tr:A0A0B4BBE9_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.29	425	242	16	57	452	255	624	1e-14	86.7
rs:WP_043327234	DNA topoisomerase I [Micromonospora sp. M42].	25.52	388	232	14	42	409	261	611	1e-14	87.0
rs:WP_037281968	DNA topoisomerase I [Ruminococcus flavefaciens].	24.71	429	265	12	43	452	227	616	1e-14	86.7
rs:WP_026459868	DNA topoisomerase I [Actinomyces suimastitidis].	27.90	362	211	13	44	384	259	591	1e-14	87.0
rs:XP_002121520	PREDICTED: DNA topoisomerase 3-beta-1 [Ciona intestinalis].	22.49	449	258	14	37	453	199	589	1e-14	86.7
rs:WP_027973723	DNA topoisomerase [Streptococcus porci].	26.87	335	201	10	74	399	278	577	1e-14	86.7
rs:WP_039192312	MULTISPECIES: hypothetical protein [unclassified Thaumarchaeota (miscellaneous)].	24.68	393	238	12	60	439	253	600	1e-14	86.7
rs:WP_028300153	DNA topoisomerase I [Oceanospirillum beijerinckii].	25.89	394	235	14	68	446	281	632	1e-14	87.0
rs:WP_018375466	DNA topoisomerase [Streptococcus orisratti].	26.87	335	201	10	74	399	278	577	1e-14	86.3
rs:WP_015044145	MULTISPECIES: DNA topoisomerase I [Dehalobacter].	23.97	459	258	15	48	449	225	649	1e-14	86.7
rs:WP_006359050	DNA topoisomerase I [Gordonia alkanivorans].	26.00	350	210	11	47	378	271	589	1e-14	87.0
rs:XP_002023181	GL21219 [Drosophila persimilis].	24.44	446	269	15	37	451	253	661	1e-14	87.0
rs:WP_003449413	DNA topoisomerase I [Clostridium perfringens].	25.00	432	253	17	47	454	224	608	1e-14	86.7
rs:WP_001698309	DNA topoisomerase I [Escherichia coli].	25.80	376	236	11	77	446	284	622	1e-14	86.7
rs:WP_016887038	DNA topoisomerase I [Mycobacterium abscessus].	26.65	379	229	11	41	399	258	607	1e-14	87.0
rs:WP_008876148	DNA topoisomerase 1 [Mesorhizobium metallidurans].	25.66	452	256	19	41	452	224	635	1e-14	86.7
rs:WP_013727870	DNA topoisomerase I [Lactobacillus buchneri].	25.24	420	243	18	55	452	255	625	1e-14	86.7
tr:K8A3X1_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.95	469	284	18	1	446	213	636	1e-14	86.7
rs:XP_004988662	DNA topoisomerase III [Salpingoeca rosetta].	23.22	422	271	13	48	450	225	612	1e-14	87.0
rs:WP_008765309	MULTISPECIES: DNA topoisomerase I [Bacteroides].	26.27	316	182	9	36	334	201	482	1e-14	86.7
rs:WP_045359707	DNA topoisomerase I [Microcystis aeruginosa].	24.34	378	238	11	41	401	249	595	1e-14	86.7
rs:WP_015216772	DNA topoisomerase I [Anabaena cylindrica].	26.14	329	200	10	77	395	285	580	1e-14	86.7
rs:WP_044654725	DNA topoisomerase I [Bacteroides acidifaciens].	26.03	315	184	8	36	334	201	482	1e-14	86.7
rs:WP_015130898	DNA topoisomerase I [Calothrix sp. PCC 7507].	25.15	342	208	10	77	401	291	601	1e-14	86.7
tr:U7TAX9_FUSNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.50	449	288	17	24	452	207	624	1e-14	86.7
rs:WP_001718167	DNA topoisomerase I [Escherichia coli].	25.80	376	236	11	77	446	284	622	1e-14	86.7
rs:WP_007006749	DNA topoisomerase I [Nitratireductor aquibiodomus].	25.74	439	254	18	47	449	230	632	1e-14	86.7
rs:WP_038316816	DNA topoisomerase I [Kingella kingae].	25.00	484	262	14	41	454	227	679	1e-14	86.7
rs:WP_038115136	DNA topoisomerase I [Veillonella sp. AS16].	26.64	304	168	12	166	454	415	678	1e-14	86.7
tr:W6LVX3_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.95	308	173	10	61	350	265	538	1e-14	86.7
rs:WP_017648495	DNA topoisomerase [Streptococcus agalactiae].	25.26	392	246	12	18	399	223	577	1e-14	86.3
rs:WP_017603757	DNA topoisomerase I [Nocardiopsis alkaliphila].	25.91	359	216	11	36	377	270	595	1e-14	86.7
rs:WP_000396295	hypothetical protein, partial [Streptococcus sp. GMD2S].	26.26	297	172	8	166	452	21	280	1e-14	85.1
rs:WP_040378997	DNA topoisomerase I, partial [Dethiobacter alkaliphilus].	26.05	430	258	16	47	457	225	613	1e-14	86.7
tr:U4TCR0_PISSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.85	414	245	14	61	452	221	594	1e-14	86.7
rs:WP_008799063	type I topoisomease [Fusobacterium nucleatum].	24.69	405	262	15	60	452	255	628	1e-14	86.7
rs:WP_024681926	DNA topoisomerase I [Pseudomonas syringae].	26.16	409	249	15	49	446	261	627	1e-14	86.7
rs:WP_002765685	DNA topoisomerase I [Microcystis aeruginosa].	24.34	378	238	11	41	401	249	595	1e-14	86.7
rs:WP_004867042	DNA topoisomerase I [Bartonella vinsonii].	25.96	443	255	16	47	452	230	636	1e-14	86.7
tr:U1DS88_ENTGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	22.36	407	250	13	65	452	27	386	1e-14	85.5
rs:WP_032984924	DNA topoisomerase I [Cronobacter condimenti].	24.95	469	284	18	1	446	199	622	1e-14	86.7
rs:WP_032823878	DNA topoisomerase I [Oenococcus oeni].	24.56	399	242	12	70	452	254	609	1e-14	86.7
rs:WP_043349418	DNA topoisomerase I, partial [Methylobacterium sp. B1].	26.53	441	241	17	48	452	9	402	1e-14	86.7
rs:WP_009491011	DNA topoisomerase I [Microvirga lotononidis].	25.00	452	262	16	34	452	227	634	1e-14	86.7
rs:WP_035396956	DNA topoisomerase I [Bacillus sp. JCM 19047].	23.00	426	267	12	47	452	224	608	1e-14	86.7
rs:WP_031410440	DNA topoisomerase I [Geobacillus vulcani].	23.41	487	300	16	1	457	170	613	1e-14	86.7
rs:WP_027253391	DNA topoisomerase I [Photobacterium halotolerans].	25.48	420	255	15	40	446	253	627	1e-14	86.7
rs:WP_024118415	DNA topoisomerase I [Helicobacter pylori].	24.77	428	258	16	41	450	218	599	1e-14	86.7
rs:WP_035067581	DNA topoisomerase I [Desulfovibrio termitidis].	25.42	417	256	14	53	452	231	609	1e-14	86.7
tr:A0A0A1MVM7_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.04	460	285	16	18	453	237	651	1e-14	86.7
rs:WP_014197383	DNA topoisomerase I [Azospirillum brasilense].	26.72	479	273	15	16	454	203	643	1e-14	86.7
rs:WP_015132934	DNA topoisomerase I [Leptolyngbya sp. PCC 7376].	26.33	376	224	9	47	399	255	600	1e-14	86.7
rs:WP_009544062	MULTISPECIES: DNA topoisomerase I [Cyanothece].	25.91	359	221	11	41	387	249	574	1e-14	86.7
rs:WP_044544802	DNA topoisomerase I, partial [Parabacteroides distasonis].	26.29	369	234	11	40	384	213	567	1e-14	86.7
rs:WP_014610724	topoisomerase I [Shewanella putrefaciens].	25.24	424	263	15	35	446	250	631	1e-14	86.7
rs:WP_012175861	DNA topoisomerase I [Desulfococcus oleovorans].	25.52	431	257	15	43	450	221	610	1e-14	86.7
rs:WP_003792156	DNA topoisomerase I [Kingella kingae].	24.79	484	263	14	41	454	227	679	1e-14	86.7
rs:WP_044360969	DNA topoisomerase I [Staphylococcus microti].	23.59	407	248	16	65	452	244	606	1e-14	86.7
rs:WP_009603934	DNA topoisomerase I [SAR116 cluster alpha proteobacterium HIMB100].	25.55	458	266	16	35	452	214	636	1e-14	86.7
tr:F6ST44_CIOIN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.49	449	258	14	37	453	226	616	1e-14	86.7
rs:WP_043397308	DNA topoisomerase I [Mycobacterium sp. UNC280MFTsu5.1].	27.11	343	199	12	55	378	281	591	1e-14	86.7
rs:WP_026751491	DNA topoisomerase I [Sediminibacterium sp. C3].	27.12	306	189	8	39	342	217	490	1e-14	86.7
rs:WP_012938598	DNA topoisomerase I, partial [Acidaminococcus fermentans].	26.09	437	218	19	77	452	255	647	1e-14	86.7
rs:WP_021845568	DNA topoisomerase [Blautia hydrogenotrophica CAG:147].	24.03	412	255	13	61	454	239	610	1e-14	86.7
tr:K9SQT0_9SYNE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.06	376	222	13	41	395	249	589	1e-14	86.7
rs:XP_012081967	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Jatropha curcas].	23.46	439	276	14	39	451	263	667	1e-14	86.7
rs:WP_010266778	DNA topoisomerase I [Corynebacterium bovis].	25.30	328	204	9	40	354	263	562	1e-14	86.7
rs:WP_026843273	DNA topoisomerase I [Geobacter bremensis].	25.78	415	239	16	65	454	274	644	1e-14	86.7
rs:WP_046871126	DNA topoisomerase I [Pediococcus damnosus].	24.71	433	254	17	43	452	240	623	1e-14	86.7
rs:XP_002732450	PREDICTED: DNA topoisomerase 3-alpha-like [Saccoglossus kowalevskii].	23.91	435	269	15	40	450	285	681	1e-14	86.7
rs:WP_038655542	DNA topoisomerase I [Mucinivorans hirudinis].	25.00	320	202	6	27	342	197	482	1e-14	86.7
rs:WP_026414122	DNA topoisomerase I [Actinomadura oligospora].	24.52	363	224	11	42	387	269	598	1e-14	86.7
rs:WP_047187102	DNA topoisomerase I [Microvirga vignae].	25.88	456	253	19	34	452	227	634	1e-14	86.7
rs:WP_003693908	DNA topoisomerase I [Lactobacillus ruminis].	23.06	425	243	16	57	452	228	597	1e-14	86.3
rs:WP_043987666	DNA topoisomerase I [Mycobacterium llatzerense].	27.11	343	199	12	55	378	281	591	1e-14	86.7
rs:WP_034072159	DNA topoisomerase I [Pseudomonas aeruginosa].	24.57	411	245	13	74	459	260	630	1e-14	86.3
rs:WP_011789092	topoisomerase I [Shewanella sp. W3-18-1].	25.24	424	263	15	35	446	250	631	1e-14	86.7
tr:D7IEM3_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.95	316	183	9	36	334	165	446	1e-14	86.7
rs:WP_014879262	DNA topoisomerase I [Phaeobacter inhibens].	26.24	465	250	21	41	454	225	647	1e-14	86.7
rs:WP_037127390	DNA topoisomerase I [Rhizobium sp. CF394].	25.06	439	267	14	47	452	230	639	1e-14	86.7
rs:WP_027069793	DNA topoisomerase I [Lysobacter defluvii].	27.03	381	220	14	65	417	253	603	1e-14	86.7
rs:WP_046922440	DNA topoisomerase I [Lactobacillus ruminis].	23.06	425	243	16	57	452	255	624	1e-14	86.7
rs:XP_006637312	PREDICTED: DNA topoisomerase 3-alpha-like [Lepisosteus oculatus].	24.83	443	269	16	40	455	295	700	1e-14	86.7
rs:WP_028046126	DNA topoisomerase I [Cellulomonas sp. URHE0023].	28.01	332	195	12	42	356	253	557	1e-14	86.7
rs:WP_012461831	DNA topoisomerase I [Orientia tsutsugamushi].	21.97	446	275	13	41	452	222	628	1e-14	86.7
rs:WP_005700469	topoisomerase I [Aggregatibacter aphrophilus].	25.07	379	235	15	77	446	290	628	1e-14	86.7
rs:WP_004513038	DNA topoisomerase I [Geobacter metallireducens].	24.02	483	263	16	43	457	228	674	1e-14	86.7
rs:WP_020088643	DNA topoisomerase I [Lactobacillus parabrevis].	24.94	437	263	15	41	457	234	625	1e-14	86.3
rs:WP_039557214	DNA topoisomerase III, partial [Vibrio vulnificus].	27.91	172	111	2	177	340	1	167	1e-14	82.0
tr:A0A060HEC6_XYLFS	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AIC11297.1};	64.18	67	17	1	123	189	3	62	1e-14	79.0
rs:WP_006680502	DNA topoisomerase I [Actinomyces turicensis].	26.23	366	221	13	42	384	252	591	1e-14	86.7
rs:WP_039232450	DNA topoisomerase I [Alteromonas macleodii].	27.08	384	208	13	8	377	239	564	1e-14	86.7
rs:WP_044447104	DNA topoisomerase I [Alteromonas australica].	26.18	401	239	16	62	446	271	630	1e-14	86.7
rs:WP_028028949	DNA topoisomerase I [Gemmobacter nectariphilus].	25.40	433	262	13	47	454	229	625	1e-14	86.7
rs:WP_046419014	DNA topoisomerase I [Streptomyces sp. MUSC136T].	26.32	342	196	12	35	354	250	557	1e-14	86.7
rs:WP_040976355	DNA topoisomerase I [Pasteurella sp. FF6].	26.77	381	226	17	77	446	290	628	1e-14	86.7
rs:WP_029330313	DNA topoisomerase I [Mycoplasma cloacale].	23.20	444	260	14	30	452	212	595	1e-14	86.3
rs:WP_046920631	DNA topoisomerase I [Lactobacillus ruminis].	23.06	425	243	16	57	452	255	624	1e-14	86.3
rs:WP_034435230	DNA topoisomerase I [Candidatus Contendobacter odensis].	26.95	308	173	10	61	350	263	536	1e-14	86.7
rs:WP_015082465	DNA topoisomerase I [Lactococcus lactis].	22.04	422	263	12	50	452	248	622	1e-14	86.3
rs:WP_017312762	DNA topoisomerase I [Fischerella sp. PCC 9339].	24.24	425	260	14	40	443	241	624	1e-14	86.3
rs:WP_025353992	DNA topoisomerase I [Kutzneria albida].	27.13	328	197	10	40	354	269	567	1e-14	86.7
rs:WP_005603755	DNA topoisomerase I [Butyrivibrio crossotus].	24.40	455	286	13	19	457	201	613	1e-14	86.3
rs:WP_041262638	DNA topoisomerase I [Flexistipes sinusarabici].	23.56	416	265	10	50	450	228	605	1e-14	86.7
tr:C0GIT5_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.05	430	258	16	47	457	225	613	1e-14	86.3
rs:WP_026898152	DNA topoisomerase I [Pedobacter oryzae].	26.22	370	202	10	60	386	233	574	1e-14	86.7
tr:K2BFF1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.28	352	219	7	35	372	234	555	1e-14	86.7
tr:F6QP60_MONDO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.04	445	271	15	40	456	206	611	1e-14	86.7
rs:WP_046640510	DNA topoisomerase I [Neorhizobium galegae].	25.06	439	266	15	47	452	230	638	1e-14	86.7
rs:WP_003471661	DNA topoisomerase I [Clostridium perfringens].	25.00	432	253	17	47	454	224	608	1e-14	86.3
rs:WP_034454831	DNA topoisomerase I [Bartonella henselae].	26.82	425	236	18	67	452	248	636	1e-14	86.7
rs:WP_008777893	MULTISPECIES: DNA topoisomerase I [Parabacteroides].	26.29	369	234	11	40	384	213	567	1e-14	86.7
rs:WP_005194610	DNA topoisomerase I [Gordonia rubripertincta].	26.00	350	210	11	47	378	271	589	1e-14	86.7
rs:WP_003475272	DNA topoisomerase I [Clostridium perfringens].	25.00	432	253	17	47	454	224	608	1e-14	86.3
tr:H5SLX2_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.22	389	213	16	89	450	2	343	1e-14	86.3
rs:WP_039361773	DNA topoisomerase I [Campylobacter fetus].	23.93	422	257	14	47	450	224	599	1e-14	86.3
rs:WP_046635455	DNA topoisomerase I [Neorhizobium galegae].	25.06	439	266	15	47	452	230	638	1e-14	86.7
rs:WP_005867659	DNA topoisomerase I [Parabacteroides sp. CAG:2].	26.29	369	234	11	40	384	237	591	1e-14	86.7
tr:A4N0B7_HAEIF	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.21	283	169	8	77	356	290	538	1e-14	85.9
rs:WP_024614709	DNA topoisomerase I [Clostridium sp. Ade.TY].	24.04	416	248	16	61	454	238	607	1e-14	86.3
rs:WP_008203491	DNA topoisomerase I [Microcystis sp. T1-4].	24.34	378	238	11	41	401	249	595	1e-14	86.7
rs:WP_033944334	DNA topoisomerase I [Pseudomonas aeruginosa].	24.82	411	244	14	74	459	260	630	1e-14	86.3
rs:WP_037031563	DNA topoisomerase I [Psychrobacter phenylpyruvicus].	27.23	415	227	21	61	452	289	651	1e-14	86.7
rs:WP_043567067	DNA topoisomerase I [Dietzia cinnamea].	26.12	356	198	12	47	377	286	601	1e-14	86.7
rs:WP_014873719	DNA topoisomerase I [Phaeobacter gallaeciensis].	26.02	465	251	20	41	454	225	647	1e-14	86.7
rs:WP_010423404	DNA topoisomerase I [Rickettsia helvetica].	24.82	415	245	17	65	449	250	627	1e-14	86.3
rs:WP_007553288	DNA topoisomerase I [Bartonella sp. DB5-6].	27.53	425	235	19	67	453	248	637	1e-14	86.7
rs:WP_003481770	DNA topoisomerase I [Clostridium perfringens].	25.00	432	253	17	47	454	224	608	1e-14	86.3
rs:WP_032126693	DNA topoisomerase I [Piscirickettsia salmonis].	25.85	414	245	14	61	452	248	621	1e-14	86.3
rs:WP_023387866	DNA topoisomerase I [Youngiibacter fragilis].	24.07	428	262	12	47	454	224	608	1e-14	86.3
rs:WP_013468922	DNA topoisomerase I [Helicobacter felis].	24.10	473	292	15	2	450	199	628	1e-14	86.3
rs:WP_008848835	DNA topoisomerase I [Halorubrum kocurii].	23.80	479	256	17	35	454	242	670	1e-14	86.7
rs:WP_002831689	DNA topoisomerase I [Pediococcus acidilactici].	25.06	415	239	17	61	452	242	607	1e-14	86.3
rs:WP_023004052	MULTISPECIES: DNA topoisomerase I [Labrenzia].	25.27	467	279	18	23	449	202	638	1e-14	86.7
rs:WP_034732693	DNA topoisomerase I [Idiomarina sp. MCCC 1A10513].	25.29	431	267	14	43	458	256	646	1e-14	86.7
rs:WP_033978938	DNA topoisomerase I [Pseudomonas aeruginosa].	25.06	411	243	14	74	459	260	630	1e-14	86.3
rs:XP_009057639	hypothetical protein LOTGIDRAFT_217319 [Lottia gigantea].	23.97	413	261	13	40	434	260	637	2e-14	86.3
rs:WP_036420687	DNA topoisomerase III, partial [Morganella morganii].	30.34	178	112	3	275	443	8	182	2e-14	83.2
tr:A0A0D6SKK9_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.11	442	262	15	47	452	189	597	2e-14	86.3
rs:WP_044056878	DNA topoisomerase I [Alteromonas australica].	26.18	401	239	16	62	446	271	630	2e-14	86.7
rs:WP_024526862	hypothetical protein [Lactobacillus brevis].	26.20	397	243	15	74	455	280	641	2e-14	86.3
rs:WP_022781580	DNA topoisomerase I [Lachnospiraceae bacterium NK4A136].	24.07	403	246	12	74	457	253	614	2e-14	86.3
rs:WP_003506900	DNA topoisomerase I [[Clostridium] symbiosum].	24.59	427	265	14	48	457	230	616	2e-14	86.3
rs:WP_012771455	topoisomerase I [Aggregatibacter aphrophilus].	25.07	379	235	15	77	446	290	628	2e-14	86.3
tr:A0A0C1R6M7_9CYAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.83	407	252	12	40	429	241	606	2e-14	86.3
rs:WP_038268119	DNA topoisomerase I [[Clostridium] litorale].	21.46	424	277	10	48	456	226	608	2e-14	86.3
rs:WP_004096816	DNA topoisomerase I [Acetonema longum].	24.31	399	245	12	77	457	256	615	2e-14	86.3
rs:WP_018358151	hypothetical protein [Porphyromonas levii].	26.78	295	178	9	45	337	221	479	2e-14	86.3
rs:WP_032850443	DNA topoisomerase I [Bacteroides sp. 1_1_14].	25.95	316	183	9	36	334	195	476	2e-14	86.3
rs:WP_031537411	DNA topoisomerase III, partial [Bacillus sp. MB2021].	32.26	155	102	2	18	169	210	364	2e-14	84.7
rs:WP_018076642	DNA topoisomerase I [Thiobacillus denitrificans].	23.75	421	257	12	51	454	231	604	2e-14	86.3
rs:WP_009433810	DNA topoisomerase I [Porphyromonas sp. oral taxon 279].	27.27	297	183	7	40	334	214	479	2e-14	86.3
rs:WP_034363738	DNA topoisomerase I [Helicobacter sp. MIT 01-6451].	25.35	434	260	15	41	454	227	616	2e-14	86.3
rs:XP_001453271	hypothetical protein [Paramecium tetraurelia strain d4-2].	23.69	363	236	10	31	385	250	579	2e-14	86.3
rs:WP_011180711	DNA topoisomerase I [Bartonella henselae].	26.82	425	236	18	67	452	248	636	2e-14	86.3
tr:S4TLK9_9CHLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.42	427	268	12	47	454	240	626	2e-14	86.3
rs:WP_036752627	DNA topoisomerase I [Peptoniphilus lacrimalis].	22.04	422	279	10	45	454	226	609	2e-14	86.3
rs:WP_006300431	DNA topoisomerase I [Aminomonas paucivorans].	24.26	470	243	17	47	449	244	667	2e-14	86.3
rs:WP_012231710	DNA topoisomerase I [Bartonella tribocorum].	26.56	433	248	17	55	452	239	636	2e-14	86.3
rs:WP_018628260	DNA topoisomerase I [Niabella aurantiaca].	26.10	318	193	9	36	351	223	500	2e-14	86.3
rs:XP_002988753	hypothetical protein SELMODRAFT_427375 [Selaginella moellendorffii].	23.39	419	261	12	61	449	474	862	2e-14	86.7
tr:A0A0F0LDR4_9MICO	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:KJL31268.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KJL31268.1};	27.36	318	176	11	51	354	268	544	2e-14	86.7
rs:WP_008174370	MULTISPECIES: topoisomerase I [Marinobacter].	25.25	396	250	14	59	446	276	633	2e-14	86.3
rs:WP_007622319	DNA topoisomerase I [Paraglaciecola arctica].	25.58	387	237	15	71	446	284	630	2e-14	86.3
rs:WP_036938706	DNA topoisomerase I [Pseudobacteroides cellulosolvens].	23.52	438	278	12	36	454	213	612	2e-14	86.3
rs:WP_030272790	DNA topoisomerase I [Streptomyces sp. NRRL B-24484].	25.80	345	194	13	37	354	252	561	2e-14	86.7
rs:WP_022869109	DNA topoisomerase I [Actinomyces vaccimaxillae].	28.00	350	197	14	77	404	289	605	2e-14	86.3
tr:E2CIT7_9RHOB	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFO31899.1};	38.64	132	78	1	257	385	1	132	2e-14	83.6
rs:WP_024862330	DNA topoisomerase I [Pediococcus acidilactici].	25.06	415	239	17	61	452	242	607	2e-14	86.3
rs:WP_032837319	DNA topoisomerase [Fusobacterium sp. CM1].	24.44	405	263	15	60	452	255	628	2e-14	86.3
rs:WP_018197579	MULTISPECIES: hypothetical protein [unclassified Cloacimonetes].	24.54	436	265	18	38	452	215	607	2e-14	86.3
tr:X8ID75_9FUSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.44	405	263	15	60	452	251	624	2e-14	86.3
rs:WP_027673005	DNA topoisomerase I [Agrobacterium larrymoorei].	26.00	423	244	15	67	452	248	638	2e-14	86.3
rs:WP_042447944	DNA topoisomerase I [Streptacidiphilus jiangxiensis].	27.27	319	184	12	77	379	306	592	2e-14	86.3
rs:WP_021616225	DNA topoisomerase I [Aggregatibacter sp. oral taxon 458].	25.33	379	234	15	77	446	290	628	2e-14	86.3
rs:WP_016464462	DNA topoisomerase I [Microbacterium sp. oral taxon 186].	28.25	400	219	16	23	392	234	595	2e-14	86.3
rs:WP_046208644	DNA topoisomerase I [Staphylococcus cohnii].	24.56	395	236	16	77	452	254	605	2e-14	86.3
tr:F8E529_FLESM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.56	416	265	10	50	450	246	623	2e-14	86.3
rs:WP_022412909	DNA topoisomerase [Clostridium sp. CAG:470].	23.17	423	272	11	47	454	226	610	2e-14	86.3
rs:WP_045915940	DNA topoisomerase I [Orientia tsutsugamushi].	21.97	446	275	13	41	452	222	628	2e-14	86.3
tr:A0A0D6AKL8_9CHRO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.63	364	242	7	47	404	255	588	2e-14	86.3
rs:WP_033185381	DNA topoisomerase I [Pseudoalteromonas sp. PLSV].	24.94	421	254	14	42	446	256	630	2e-14	86.3
rs:WP_016119511	hypothetical protein, partial [Bacillus cereus].	25.00	252	176	5	35	282	239	481	2e-14	85.5
rs:WP_025567201	MULTISPECIES: DNA topoisomerase I [Deinococcus].	26.40	322	186	11	40	344	254	541	2e-14	86.3
rs:WP_022280660	DNA topoisomerase [Lactobacillus ruminis CAG:367].	23.06	425	243	16	57	452	255	624	2e-14	86.3
rs:WP_002712162	DNA topoisomerase I [Afipia clevelandensis].	26.79	433	241	14	60	454	243	637	2e-14	86.3
rs:WP_000513595	DNA topoisomerase 1 [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	86.3
rs:WP_032820757	DNA topoisomerase I [Oenococcus oeni].	24.31	399	243	11	70	452	254	609	2e-14	86.3
rs:WP_005568750	topoisomerase I [Aggregatibacter actinomycetemcomitans].	23.67	376	244	11	77	446	290	628	2e-14	86.3
rs:WP_035221505	DNA topoisomerase, partial [Acidobacteriaceae bacterium KBS 83].	22.77	448	276	14	33	446	215	626	2e-14	86.3
rs:WP_007454679	DNA topoisomerase I [Micromonospora lupini].	25.48	365	218	13	42	386	261	591	2e-14	86.3
rs:WP_024853033	DNA topoisomerase I [[Ruminococcus] gnavus].	24.00	425	271	12	48	457	227	614	2e-14	86.3
rs:WP_030606321	DNA topoisomerase I [Streptomyces achromogenes].	26.32	342	196	12	35	354	250	557	2e-14	86.3
rs:WP_001669681	DNA topoisomerase I [Escherichia coli].	24.83	443	283	13	10	446	224	622	2e-14	86.3
rs:WP_045273629	DNA topoisomerase I [Microbacterium azadirachtae].	27.36	318	176	11	51	354	253	529	2e-14	86.3
rs:WP_032881383	DNA topoisomerase [Fusobacterium nucleatum].	24.28	449	289	17	24	452	211	628	2e-14	86.3
rs:XP_012081965	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Jatropha curcas].	23.46	439	276	14	39	451	263	667	2e-14	86.3
rs:WP_034214990	DNA topoisomerase I [Lachnoanaerobaculum sp. MSX33].	24.21	442	278	12	34	457	214	616	2e-14	86.3
rs:WP_023364833	hypothetical protein [Spiribacter sp. UAH-SP71].	27.46	335	194	11	61	377	264	567	2e-14	86.3
rs:WP_007994801	DNA topoisomerase I [Halorubrum arcis].	24.68	466	268	17	35	454	242	670	2e-14	86.3
rs:WP_021214322	DNA topoisomerase I, partial [Lactococcus lactis].	22.04	422	263	12	50	452	15	389	2e-14	85.5
tr:W5MC34_LEPOC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.83	443	269	16	40	455	295	700	2e-14	86.3
rs:WP_046284851	DNA topoisomerase I [Mycobacterium sp. UM_NZ2].	27.62	344	197	12	77	399	307	619	2e-14	86.3
tr:A0A0F2QU11_9DELT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJS29898.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KJS29898.1};	24.90	506	278	19	1	459	166	616	2e-14	86.3
rs:XP_005966779	PREDICTED: DNA topoisomerase 3-alpha-like [Pantholops hodgsonii].	25.68	444	257	16	47	452	230	638	2e-14	86.3
rs:WP_023628782	DNA topoisomerase I [Pseudomonas mosselii].	23.00	400	262	13	69	454	255	622	2e-14	85.9
rs:WP_023103773	DNA topoisomerase I [Pseudomonas aeruginosa].	24.82	411	244	14	74	459	260	630	2e-14	85.9
rs:WP_011575153	topoisomerase I [Pseudoalteromonas atlantica].	25.59	422	250	16	42	446	256	630	2e-14	86.3
rs:WP_043114455	DNA topoisomerase I [Solimonas soli].	28.20	344	190	12	61	377	248	561	2e-14	86.3
rs:WP_023440369	DNA topoisomerase I [Pediococcus pentosaceus].	25.06	415	239	17	61	452	242	607	2e-14	85.9
rs:WP_008724189	DNA topoisomerase I [Brachyspira hampsonii].	21.88	457	264	17	47	449	249	666	2e-14	86.3
rs:WP_021961263	DNA topoisomerase [Butyrivibrio crossotus CAG:259].	24.40	455	286	13	19	457	201	613	2e-14	85.9
rs:WP_026598814	DNA topoisomerase I [Methylocystis sp. LW5].	25.70	428	247	14	60	452	243	634	2e-14	86.3
rs:WP_013052041	topoisomerase I [Shewanella violacea].	26.01	346	209	11	57	388	271	583	2e-14	86.3
tr:A0A068RFI3_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.84	344	209	11	40	371	257	559	2e-14	85.9
rs:WP_000513596	topoisomerase I [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	86.3
rs:WP_001680391	topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	2e-14	86.3
rs:WP_015181243	DNA topoisomerase I [Microcoleus sp. PCC 7113].	25.52	337	215	7	40	370	248	554	2e-14	86.3
rs:WP_013889345	DNA topoisomerase I [Corynebacterium resistens].	25.20	369	228	10	31	377	248	590	2e-14	86.3
rs:WP_015702243	topoisomerase I [Haemophilus influenzae].	25.33	379	234	13	77	446	290	628	2e-14	86.3
rs:WP_045161401	DNA topoisomerase I [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	86.3
tr:T0TNZ7_LACLC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	22.04	422	263	12	50	452	27	401	2e-14	85.5
rs:WP_008002399	DNA topoisomerase I [Halorubrum aidingense].	24.41	467	268	16	35	454	242	670	2e-14	86.3
rs:WP_039964283	DNA topoisomerase I, partial [Wolbachia endosymbiont of Drosophila ananassae].	26.30	403	225	15	83	452	1	364	2e-14	85.5
rs:WP_046623771	DNA topoisomerase I [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	86.3
rs:WP_015836835	DNA topoisomerase I [Geobacter sp. M21].	26.02	415	238	17	65	454	274	644	2e-14	86.3
rs:WP_023198122	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	26.79	377	231	14	77	446	284	622	2e-14	85.9
tr:A0A024LSJ9_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.25	422	238	18	67	452	248	636	2e-14	86.3
rs:WP_004821709	DNA topoisomerase I [Peptoniphilus indolicus].	24.14	406	257	14	61	454	242	608	2e-14	85.9
rs:WP_022085983	GTP-sensing transcriptional pleiotropic repressor CodY [Roseburia sp. CAG:197].	24.12	427	262	12	48	454	227	611	2e-14	85.9
rs:WP_000513594	topoisomerase I [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	86.3
rs:WP_027452456	DNA topoisomerase I [Prevotella albensis].	27.69	260	156	7	77	334	252	481	2e-14	86.3
rs:WP_005659000	DNA topoisomerase I [Dethiosulfovibrio peptidovorans].	25.68	444	243	17	47	457	243	632	2e-14	85.9
rs:WP_012177809	DNA topoisomerase I [Dinoroseobacter shibae].	26.71	468	234	19	51	454	245	667	2e-14	86.3
tr:A0A0D6B246_RHOSU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.68	474	255	15	47	452	231	670	2e-14	86.3
rs:WP_045662395	DNA topoisomerase I [Rhodospirillaceae bacterium BRH_c57].	26.55	467	268	19	28	454	212	643	2e-14	86.3
rs:WP_002945497	DNA topoisomerase I [Campylobacter rectus].	25.36	422	251	16	47	450	224	599	2e-14	85.9
rs:XP_010907414	PREDICTED: DNA topoisomerase 3-alpha [Elaeis guineensis].	25.70	467	263	17	24	452	254	674	2e-14	86.3
rs:WP_005253290	DNA topoisomerase I [Acinetobacter sp. CIP 102136].	24.55	444	274	16	22	459	216	604	2e-14	85.9
rs:WP_023253082	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	26.79	377	231	14	77	446	284	622	2e-14	85.9
rs:WP_021037269	DNA topoisomerase I TopA [Lactococcus lactis].	22.04	422	263	12	50	452	246	620	2e-14	85.9
tr:S6F3I0_LACLL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.56	422	265	12	50	452	200	574	2e-14	85.9
rs:WP_031909847	DNA topoisomerase III, partial [Staphylococcus aureus].	24.62	260	175	6	35	293	248	487	2e-14	85.5
rs:WP_020479289	DNA topoisomerase I [Sinorhizobium meliloti].	24.20	438	271	13	47	452	230	638	2e-14	86.3
tr:E6J7R6_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.12	356	198	12	47	377	272	587	2e-14	86.3
rs:WP_045677419	DNA topoisomerase I [Desulfatitalea sp. BRH_c12].	24.90	506	278	19	1	459	171	621	2e-14	85.9
rs:WP_036856688	DNA topoisomerase I, partial [Prevotella amnii].	26.74	258	166	7	22	271	221	463	2e-14	85.5
tr:U1M2T6_ASCSU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.60	375	231	13	27	388	421	760	2e-14	86.3
rs:WP_016506808	DNA topoisomerase 1 [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	86.3
rs:WP_035491918	DNA topoisomerase I [Gammaproteobacteria bacterium MOLA455].	24.76	412	234	16	68	452	284	646	2e-14	86.3
rs:WP_027330922	DNA topoisomerase I [Marinimicrobium agarilyticum].	25.12	422	266	13	42	452	260	642	2e-14	86.3
rs:WP_036442596	DNA topoisomerase I [Mycobacterium vulneris].	27.81	356	203	13	77	410	303	626	2e-14	86.3
rs:WP_027508567	DNA topoisomerase I [Rhizobium sullae].	25.73	443	258	15	47	452	230	638	2e-14	86.3
rs:WP_047658707	DNA topoisomerase I, partial [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	85.9
rs:WP_045978387	DNA topoisomerase I [Pseudoalteromonas ruthenica].	25.12	422	252	16	42	446	257	631	2e-14	86.3
tr:R5I715_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.15	439	274	13	34	454	212	609	2e-14	85.9
rs:WP_008214692	DNA topoisomerase I [Lactobacillus parafarraginis].	24.32	407	243	16	65	452	261	621	2e-14	85.9
tr:A0A0E9G4U1_CHLTH	SubName: Full=DNA topoisomerase I-fused to SWI domain {ECO:0000313|EMBL:CRH89684.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRH89684.1};	26.87	361	213	13	46	384	260	591	2e-14	86.3
rs:WP_023212465	DNA topoisomerase I subunit omega [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	86.3
rs:WP_015720878	DNA topoisomerase I [Geobacter sp. M18].	25.78	415	239	17	65	454	274	644	2e-14	85.9
tr:E2NDW4_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.25	301	182	7	40	334	226	492	2e-14	85.9
rs:WP_017292861	DNA topoisomerase I [Geminocystis herdmanii].	24.69	397	243	10	47	417	255	621	2e-14	86.3
rs:WP_003496397	DNA topoisomerase I [Agrobacterium tumefaciens].	25.96	443	257	16	47	452	230	638	2e-14	86.3
rs:WP_005631659	topoisomerase I [Haemophilus haemolyticus].	25.59	379	233	14	77	446	290	628	2e-14	86.3
tr:A0A068BCF9_COCNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.95	465	269	18	24	452	254	674	2e-14	86.3
rs:WP_007487544	DNA topoisomerase I [Bacteroides nordii].	25.00	316	186	8	36	334	201	482	2e-14	85.9
rs:WP_022945094	topoisomerase I [Pseudoalteromonas ruthenica].	25.12	422	252	16	42	446	257	631	2e-14	86.3
rs:WP_015638932	DNA topoisomerase I [Lactobacillus fermentum].	25.36	414	230	20	65	452	267	627	2e-14	85.9
rs:WP_028129147	DNA topoisomerase I [Selenomonas sp. AE3005].	25.69	436	255	15	45	456	253	643	2e-14	85.9
tr:A0A0D5LX21_ACIBA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.63	394	241	14	72	459	257	604	2e-14	85.9
rs:WP_009438447	DNA topoisomerase I [Selenomonas sp. oral taxon 137].	25.78	446	265	15	31	457	236	634	2e-14	85.9
rs:WP_012531141	DNA topoisomerase I [Geobacter bemidjiensis].	26.02	415	238	17	65	454	274	644	2e-14	85.9
tr:K1WYH2_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	23.50	417	260	13	48	452	10	379	2e-14	85.1
rs:WP_046966935	DNA topoisomerase I [Luteibacter rhizovicinus].	28.45	362	206	15	66	405	254	584	2e-14	85.9
rs:WP_010703721	DNA topoisomerase I [Bartonella schoenbuchensis].	27.25	422	238	18	67	452	248	636	2e-14	85.9
rs:WP_021866070	DNA topoisomerase [Eubacterium sp. CAG:86].	24.77	428	264	13	47	457	226	612	2e-14	85.9
rs:WP_039968868	DNA topoisomerase I [Selenomonas artemidis].	25.78	446	265	15	31	457	236	634	2e-14	85.9
rs:WP_002558218	MULTISPECIES: DNA topoisomerase I [Bacteroides].	25.00	316	186	8	36	334	201	482	2e-14	85.9
tr:E6YZ97_BARSR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.25	422	238	18	67	452	248	636	2e-14	85.9
tr:D4A6J4_RAT	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSRNOP00000061212};	25.24	420	254	15	60	455	310	693	2e-14	86.3
rs:WP_023155299	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	2e-14	85.9
rs:WP_017609913	DNA topoisomerase I [Nocardiopsis xinjiangensis].	25.63	355	214	11	42	379	277	598	2e-14	86.3
rs:WP_005540121	DNA topoisomerase I [Johnsonella ignava].	24.12	427	263	14	47	454	227	611	2e-14	85.9
rs:WP_033861626	DNA topoisomerase III, partial [Staphylococcus aureus].	31.43	175	110	5	278	450	2	168	2e-14	82.8
tr:Q07L73_RHOP5	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.46	427	250	14	60	454	268	662	2e-14	86.3
rs:WP_001527825	topoisomerase I [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	85.9
tr:N9XV23_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	24.73	275	185	10	74	345	286	541	2e-14	85.5
gp:CP007584_1792	DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Anatum str.]	26.33	376	234	12	77	446	286	624	2e-14	85.9
rs:WP_022183068	DNA topoisomerase [Clostridium sp. CAG:575].	22.75	422	273	12	48	454	227	610	2e-14	85.9
rs:WP_028954489	DNA topoisomerase I [Synechocystis sp. PCC 7509].	25.14	370	219	11	30	386	232	556	2e-14	85.9
tr:K2E740_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	27.25	422	229	19	65	452	251	628	2e-14	85.9
rs:WP_003683147	DNA topoisomerase I [Lactobacillus fermentum].	25.36	414	230	20	65	452	267	627	2e-14	85.9
rs:WP_013221847	DNA topoisomerase I [Nitrosococcus watsonii].	25.47	373	214	10	35	377	223	561	2e-14	85.9
rs:WP_035709856	DNA topoisomerase I [Bradyrhizobium sp. CCBAU 43298].	25.12	426	250	13	61	452	244	634	2e-14	85.9
rs:WP_033742789	DNA topoisomerase I [Helicobacter pylori].	24.65	426	261	14	41	450	218	599	2e-14	85.9
gp:CP006631_2795	DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Newport str.]	26.33	376	234	12	77	446	286	624	2e-14	85.9
tr:A0A0F6DPV6_SALTM	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:AIE05596.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AIE05596.1};	26.33	376	234	12	77	446	286	624	2e-14	85.9
rs:WP_039972512	DNA topoisomerase I [Bacteroides pyogenes].	26.94	297	183	8	47	340	223	488	2e-14	85.9
rs:WP_035107542	DNA topoisomerase I, partial [Desulfovirgula thermocuniculi].	23.37	445	271	14	36	454	214	614	2e-14	85.9
rs:WP_024237790	DNA topoisomerase I [Escherichia coli].	25.98	381	229	12	77	446	284	622	2e-14	85.9
rs:WP_009658146	DNA topoisomerase I [Selenomonas sp. FOBRC9].	25.78	446	265	15	31	457	236	634	2e-14	85.9
rs:WP_026222843	DNA topoisomerase I [Methylocystis rosea].	27.23	415	223	17	77	452	260	634	2e-14	85.9
rs:WP_015750544	DNA topoisomerase I [Desulfohalobium retbaense].	26.05	403	241	15	65	452	244	604	2e-14	85.9
rs:WP_000513591	DNA topoisomerase 1 [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	85.9
tr:A0A0A8W477_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.24	313	205	11	49	357	252	539	2e-14	85.9
rs:WP_037349343	DNA topoisomerase I [Selenomonas artemidis].	25.78	446	265	15	31	457	236	634	2e-14	85.9
rs:WP_044283427	DNA topoisomerase I, partial [Candidatus Endolissoclinum faulkneri].	24.83	435	272	13	47	452	231	639	2e-14	85.9
rs:WP_022243320	GTP-sensing transcriptional pleiotropic repressor CodY [Roseburia sp. CAG:45].	23.82	424	269	12	47	454	228	613	2e-14	85.9
rs:WP_014828436	DNA topoisomerase I [Desulfosporosinus acidiphilus].	25.79	411	248	14	66	457	244	616	2e-14	85.9
tr:I1FRL5_AMPQE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.49	441	271	13	40	454	264	668	2e-14	85.9
rs:WP_038395914	DNA topoisomerase I [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	85.9
rs:WP_023138314	DNA topoisomerase I [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	85.9
rs:WP_011174621	DNA topoisomerase I [Candidatus Protochlamydia amoebophila].	23.76	425	269	14	47	454	240	626	2e-14	85.9
rs:WP_023020431	MULTISPECIES: DNA topoisomerase I [Corynebacterium].	25.27	372	210	13	38	384	265	593	2e-14	85.9
rs:WP_045716645	DNA topoisomerase I, partial [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	85.9
rs:WP_035678852	DNA topoisomerase I [Bradyrhizobium liaoningense].	25.29	427	250	14	60	452	243	634	2e-14	85.9
rs:WP_028181330	MULTISPECIES: DNA topoisomerase I [Bradyrhizobium].	25.29	427	250	14	60	452	243	634	2e-14	85.9
rs:WP_022210546	MULTISPECIES: DNA topoisomerase [Bacteroides].	26.25	301	182	7	40	334	216	482	2e-14	85.9
tr:U4PWA0_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.11	442	262	15	47	452	230	638	2e-14	85.9
rs:WP_000513587	topoisomerase I [Salmonella enterica].	26.33	376	234	12	77	446	298	636	2e-14	85.9
rs:WP_001633920	DNA topoisomerase 1 [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	85.9
rs:WP_000513592	topoisomerase I [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	85.9
rs:WP_048340062	DNA topoisomerase I [Lactobacillus fermentum].	25.36	414	230	20	65	452	267	627	2e-14	85.9
rs:WP_026662512	DNA topoisomerase I [Butyrivibrio proteoclasticus].	22.95	427	266	13	48	454	223	606	2e-14	85.9
rs:WP_010473233	DNA topoisomerase I [Streptomyces somaliensis].	26.22	328	193	11	42	354	264	557	2e-14	85.9
rs:WP_027989610	DNA topoisomerase I [Sinorhizobium meliloti].	24.20	438	271	13	47	452	230	638	2e-14	85.9
rs:WP_039355843	DNA topoisomerase I [Candidatus Protochlamydia amoebophila].	23.76	425	269	14	47	454	240	626	2e-14	85.9
rs:WP_017864498	DNA topoisomerase I [Lactococcus lactis].	21.56	422	265	12	50	452	250	624	2e-14	85.9
rs:WP_022281084	DNA topoisomerase [Clostridium sp. CAG:448].	25.34	442	264	15	40	454	217	619	2e-14	85.9
tr:A0A0E5RY56_SALTI	SubName: Full=DNA topoisomerase I%2C omega protein I {ECO:0000313|EMBL:CQW12457.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CQW12457.1};	26.33	376	234	12	77	446	284	622	2e-14	85.9
rs:WP_023243911	DNA topoisomerase 1 [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	85.9
rs:WP_000513582	topoisomerase I [Salmonella bongori].	26.33	376	234	12	77	446	284	622	2e-14	85.9
sp:TOP1_SALTI	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	26.33	376	234	12	77	446	284	622	2e-14	85.9
rs:WP_034129460	DNA topoisomerase I [Acinetobacter baumannii].	24.32	444	275	16	22	459	216	604	2e-14	85.9
rs:WP_007219376	DNA topoisomerase I [Bacteroides cellulosilyticus].	26.25	301	182	7	40	334	216	482	2e-14	85.9
rs:WP_044263883	DNA topoisomerase I [Candidatus Bacteroides timonensis].	26.25	301	182	7	40	334	216	482	2e-14	85.9
rs:WP_032134845	DNA topoisomerase I [Alistipes sp. AL-1].	24.92	309	188	7	40	340	214	486	2e-14	85.9
rs:WP_039294073	DNA topoisomerase I [Cedecea neteri].	26.60	376	233	12	77	446	284	622	2e-14	85.9
rs:WP_047657007	DNA topoisomerase I [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	85.9
tr:G1QHD0_NOMLE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.40	423	258	15	25	424	203	582	2e-14	85.5
rs:WP_033627287	DNA topoisomerase, partial [Enterococcus faecium].	31.68	202	125	5	52	247	40	234	2e-14	82.4
rs:WP_047827503	DNA topoisomerase I [Peptococcaceae bacterium CEB3].	26.13	463	257	15	48	456	225	656	2e-14	85.9
rs:WP_041415332	DNA topoisomerase I [Sinorhizobium fredii].	24.66	438	269	13	47	452	230	638	2e-14	85.9
rs:WP_041800896	DNA topoisomerase I [Rhodopseudomonas palustris].	26.46	427	250	14	60	454	243	637	2e-14	85.9
rs:WP_023074624	dna topoisomerase i [Leptolyngbya sp. Heron Island J].	26.30	346	220	9	41	379	249	566	2e-14	85.9
tr:K7ZDL5_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.83	435	272	13	47	452	231	639	2e-14	85.9
rs:WP_005407451	DNA topoisomerase I [Acinetobacter radioresistens].	25.63	394	241	14	72	459	257	604	2e-14	85.9
tr:V2KZL9_SALET	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.33	376	234	12	77	446	284	622	2e-14	85.9
rs:WP_011225888	DNA topoisomerase I [Streptococcus thermophilus].	24.21	409	239	14	65	452	270	628	2e-14	85.9
rs:WP_034495748	MULTISPECIES: DNA topoisomerase I [Rhizobium/Agrobacterium group].	25.11	442	262	15	47	452	230	638	2e-14	85.9
rs:WP_018696524	DNA topoisomerase I [Alistipes onderdonkii].	24.92	309	188	7	40	340	214	486	2e-14	85.9
rs:WP_039503944	DNA topoisomerase I [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	85.9
rs:WP_023206147	DNA topoisomerase I subunit omega [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	85.9
rs:WP_005942380	hypothetical protein, partial [Faecalibacterium prausnitzii].	32.26	186	112	4	114	295	1	176	2e-14	81.6
rs:WP_028011292	DNA topoisomerase I [Sinorhizobium meliloti].	24.20	438	271	13	47	452	230	638	2e-14	85.9
rs:WP_003533027	DNA topoisomerase I [Sinorhizobium meliloti].	24.20	438	271	13	47	452	230	638	2e-14	85.9
rs:WP_039384579	DNA topoisomerase I [Pantoea sp. PSNIH1].	28.06	392	224	17	77	452	284	633	2e-14	85.9
rs:WP_000513585	topoisomerase I [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	85.9
rs:WP_014572601	DNA topoisomerase I [Lactococcus lactis].	22.04	422	263	12	50	452	248	622	2e-14	85.9
tr:K1Z1A0_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.30	460	267	14	47	449	227	648	2e-14	85.5
rs:WP_021211410	DNA topoisomerase I [Lactococcus lactis].	22.04	422	263	12	50	452	250	624	2e-14	85.9
rs:WP_038276105	DNA topoisomerase I, partial [actinobacterium acAMD-5].	27.99	343	195	13	24	354	231	533	2e-14	85.9
rs:WP_035500988	DNA topoisomerase I [Fusobacterium gonidiaformans].	26.96	319	183	9	75	378	250	533	2e-14	85.9
rs:WP_013034676	DNA topoisomerase I [Nitrosococcus halophilus].	27.20	364	200	12	45	377	233	562	2e-14	85.9
rs:WP_026031461	DNA topoisomerase I [Sinorhizobium meliloti].	24.20	438	271	13	47	452	228	636	2e-14	85.9
rs:XP_012226746	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Linepithema humile].	24.50	400	243	12	73	449	291	654	2e-14	85.9
rs:WP_023189256	DNA topoisomerase 1 [Lactococcus lactis].	21.56	422	265	12	50	452	250	624	2e-14	85.9
rs:WP_015426411	DNA topoisomerase I [Lactococcus lactis].	21.56	422	265	12	50	452	250	624	2e-14	85.9
rs:WP_000513597	topoisomerase I [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	85.9
rs:WP_038960642	DNA topoisomerase I [Atribacteria bacterium SCGC AB-164-A22].	23.96	434	260	14	47	456	227	614	2e-14	85.5
rs:WP_003458449	DNA topoisomerase I [Clostridium perfringens].	25.00	432	253	17	47	454	224	608	2e-14	85.5
sp:TOP1_LACLA	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	21.56	422	265	12	50	452	250	624	2e-14	85.9
tr:K8BJP2_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	25.32	470	281	18	1	446	4	427	2e-14	85.5
rs:WP_019106970	DNA topoisomerase I [Peptoniphilus senegalensis].	22.35	425	271	13	47	454	228	610	2e-14	85.5
rs:WP_018788790	DNA topoisomerase I [Micromonospora sp. CNB394].	25.52	388	232	14	42	409	261	611	2e-14	85.9
rs:WP_028002973	DNA topoisomerase I [Sinorhizobium meliloti].	24.20	438	271	13	47	452	230	638	2e-14	85.9
rs:WP_023240746	DNA topoisomerase 1 [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	85.9
rs:WP_000513581	DNA topoisomerase I subunit omega [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	85.9
tr:A0A0A1SBJ6_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.24	313	205	11	49	357	252	539	2e-14	85.5
rs:WP_036227104	DNA topoisomerase I [Marmoricola sp. URHB0036].	30.07	296	155	13	77	356	294	553	2e-14	85.9
rs:WP_038600921	DNA topoisomerase I [Lactococcus lactis].	21.56	422	265	12	50	452	250	624	2e-14	85.5
rs:WP_021756983	DNA topoisomerase [Chlamydia pecorum].	25.88	398	223	18	77	449	271	621	2e-14	85.9
rs:WP_015808006	DNA topoisomerase I [Pedobacter heparinus].	27.30	304	174	9	36	334	219	480	2e-14	85.9
tr:U2CMC3_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.15	291	178	8	47	334	238	497	2e-14	85.9
rs:WP_014570604	DNA topoisomerase 1 [Lactococcus lactis].	21.56	422	265	12	50	452	250	624	2e-14	85.5
rs:WP_021331401	DNA topoisomerase I [Treponema socranskii].	23.61	432	266	16	41	452	231	618	2e-14	85.5
rs:WP_044253769	DNA topoisomerase I [Isosphaera pallida].	23.24	469	255	15	45	453	229	652	2e-14	85.9
rs:WP_023168632	DNA topoisomerase I subunit omega [Salmonella enterica].	26.33	376	234	12	77	446	284	622	2e-14	85.9
rs:WP_027025237	DNA topoisomerase I [Mesorhizobium sp. URHA0056].	26.05	453	253	20	41	452	224	635	2e-14	85.9
rs:WP_023505674	DNA topoisomerase I [uncultured archaeon A07HR60].	23.58	458	278	13	40	454	251	679	2e-14	85.9
rs:WP_028006081	DNA topoisomerase I [Sinorhizobium meliloti].	24.20	438	271	13	47	452	230	638	2e-14	85.9
rs:WP_038391634	DNA topoisomerase I [Salmonella bongori].	26.33	376	234	12	77	446	284	622	2e-14	85.9
rs:WP_025903084	MULTISPECIES: DNA topoisomerase I [Tatumella].	26.65	394	227	15	77	452	284	633	2e-14	85.9
rs:WP_033899618	DNA topoisomerase I [Lactococcus lactis].	21.56	422	265	12	50	452	250	624	2e-14	85.5
rs:WP_020719565	hypothetical protein [Acidobacteriaceae bacterium KBS 96].	24.20	405	252	12	69	452	267	637	2e-14	85.9
rs:WP_037452940	DNA topoisomerase I [Skermanella stibiiresistens].	26.02	465	268	17	28	452	215	643	2e-14	85.9
rs:WP_024581368	MULTISPECIES: DNA topoisomerase I [Bradyrhizobium].	25.48	416	247	12	70	454	253	636	2e-14	85.9
rs:WP_006435073	DNA topoisomerase I [Gordonia amicalis].	25.47	369	213	11	41	378	265	602	2e-14	85.9
tr:A0A0A1NEC9_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.04	460	285	16	18	453	237	651	2e-14	85.9
rs:WP_038534859	MULTISPECIES: DNA topoisomerase I [Mycobacterium avium complex (MAC)].	25.26	380	232	11	41	399	271	619	2e-14	85.9
rs:XP_004896708	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Heterocephalus glaber].	24.47	470	261	16	40	455	289	718	2e-14	85.9
rs:WP_021949393	DNA topoisomerase [Prevotella sp. CAG:1124].	25.96	312	194	8	27	334	13	291	2e-14	85.5
rs:WP_040089153	DNA topoisomerase 1 [Escherichia coli].	26.33	376	234	12	77	446	284	622	2e-14	85.9
rs:WP_037096283	DNA topoisomerase I [Rhizobium alamii].	25.45	440	264	14	47	452	230	639	2e-14	85.9
rs:WP_028770836	DNA topoisomerase I [Silanimonas lenta].	29.64	307	167	11	65	354	254	528	2e-14	85.9
rs:XP_003386887	PREDICTED: DNA topoisomerase 3-alpha-like [Amphimedon queenslandica].	24.49	441	271	13	40	454	264	668	2e-14	85.9
tr:I3X7P4_RHIFR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.66	438	269	13	47	452	232	640	2e-14	85.9
rs:WP_037080464	DNA topoisomerase I [Rhizobium vignae].	25.06	439	266	15	47	452	230	638	2e-14	85.9
rs:WP_020479433	DNA topoisomerase I [Sinorhizobium meliloti].	24.20	438	271	13	47	452	232	640	2e-14	85.9
rs:WP_023384164	DNA topoisomerase I [Campylobacter fetus].	23.93	422	257	14	47	450	224	599	3e-14	85.5
rs:WP_016660865	DNA topoisomerase I [Bacteroides stercoris].	26.25	301	182	7	40	334	216	482	3e-14	85.9
rs:WP_038302802	DNA topoisomerase I [Kingella kingae].	25.75	431	262	11	41	452	227	618	3e-14	85.5
rs:WP_000513598	topoisomerase I [Salmonella enterica].	26.33	376	234	12	77	446	284	622	3e-14	85.9
rs:WP_032971091	DNA topoisomerase I [Cronobacter malonaticus].	25.32	470	281	18	1	446	199	622	3e-14	85.9
rs:WP_029052307	DNA topoisomerase I [Sporosarcina ureae].	21.83	481	305	17	1	452	170	608	3e-14	85.5
rs:WP_009267877	DNA topoisomerase I [Lachnospiraceae bacterium 1_4_56FAA].	24.65	426	267	11	48	457	227	614	3e-14	85.5
rs:XP_002672722	predicted protein [Naegleria gruberi].	23.88	356	227	10	39	385	283	603	3e-14	85.9
rs:WP_022095931	DNA topoisomerase [Clostridium sp. CAG:568].	25.17	433	261	15	36	450	211	598	3e-14	85.5
rs:WP_038880283	DNA topoisomerase I [Cronobacter sakazakii].	25.32	470	281	18	1	446	129	552	3e-14	85.9
tr:A0A094PGW1_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.99	343	195	13	24	354	231	533	3e-14	85.9
rs:WP_001553967	DNA topoisomerase I [Escherichia coli].	24.83	443	283	13	10	446	224	622	3e-14	85.9
rs:WP_028163942	DNA topoisomerase I [Bradyrhizobium elkanii].	24.77	428	253	14	61	454	244	636	3e-14	85.9
rs:WP_003717034	DNA topoisomerase I [Lactobacillus vaginalis].	26.03	411	231	21	65	452	265	625	3e-14	85.5
rs:WP_012498147	DNA topoisomerase I [Mycoplasma arthritidis].	26.08	418	240	16	48	450	230	593	3e-14	85.5
rs:WP_019204639	topoisomerase I, partial [Acinetobacter baumannii].	26.33	395	239	17	61	446	5	356	3e-14	85.5
rs:WP_032968854	DNA topoisomerase I, partial [Cronobacter malonaticus].	25.32	470	281	18	1	446	14	437	3e-14	85.5
rs:WP_029959672	DNA topoisomerase I [Ensifer sp. USDA 6670].	23.86	440	270	14	47	452	230	638	3e-14	85.9
rs:WP_007477343	DNA topoisomerase I [Bartonella melophagi].	26.01	419	247	16	67	452	248	636	3e-14	85.9
rs:WP_023875927	DNA topoisomerase I [Pseudomonas aeruginosa].	24.69	405	252	13	74	459	260	630	3e-14	85.5
tr:E5BEB8_9FUSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.96	319	183	9	75	378	256	539	3e-14	85.5
rs:WP_040275379	DNA topoisomerase I [Streptomonospora alba].	25.00	352	220	10	42	379	278	599	3e-14	85.9
rs:WP_038803946	DNA topoisomerase I, partial [Salmonella enterica].	26.33	376	234	12	77	446	284	622	3e-14	85.9
rs:WP_017740381	DNA topoisomerase I [Scytonema hofmanni].	24.93	349	221	9	41	379	253	570	3e-14	85.9
rs:WP_016288835	DNA topoisomerase I [Lachnospiraceae bacterium 3-1].	25.50	400	244	12	74	457	253	614	3e-14	85.5
rs:XP_004832692	DNA topoisomerase III, putative [Babesia equi].	24.32	370	228	12	40	394	255	587	3e-14	85.5
rs:WP_004578652	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	26.33	376	234	12	77	446	284	622	3e-14	85.9
tr:E7MZJ2_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.78	446	265	15	31	457	250	648	3e-14	85.5
tr:R9C509_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.43	161	97	3	18	169	210	364	3e-14	84.0
rs:WP_020493125	DNA topoisomerase I [Dehalobacter sp. FTH1].	23.97	459	258	15	48	449	225	649	3e-14	85.5
rs:WP_018014634	topoisomerase I [Teredinibacter turnerae].	25.36	422	265	13	42	452	261	643	3e-14	85.9
rs:WP_040343003	DNA topoisomerase III, partial [Bacillus nealsonii].	30.43	161	97	3	18	169	210	364	3e-14	84.0
rs:WP_046948315	DNA topoisomerase I [Lactobacillus fermentum].	25.36	414	230	20	65	452	265	625	3e-14	85.5
rs:WP_042281596	DNA topoisomerase I [Candidatus Protochlamydia sp. R18].	23.76	425	269	14	47	454	240	626	3e-14	85.9
tr:F2QD08_STROU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.16	389	228	12	60	428	248	589	3e-14	85.5
tr:A0A023F3Y2_TRIIF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.71	437	257	17	40	453	262	649	3e-14	85.9
rs:WP_043623982	DNA topoisomerase I [Chromobacterium piscinae].	25.59	426	251	13	49	452	233	614	3e-14	85.5
rs:WP_002677701	DNA topoisomerase I [Treponema denticola].	24.71	433	270	15	36	452	232	624	3e-14	85.5
rs:WP_037177574	DNA topoisomerase I [Rhizobium sp. YR519].	25.51	439	264	15	47	452	230	638	3e-14	85.9
rs:WP_020863281	DNA topoisomerase III [Candidatus Caldiarchaeum subterraneum].	26.49	336	200	11	53	381	253	548	3e-14	85.5
tr:X5L696_9MYCO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.81	356	203	13	77	410	287	610	3e-14	85.9
rs:WP_000513589	topoisomerase I [Salmonella enterica].	26.33	376	234	12	77	446	284	622	3e-14	85.9
rs:WP_041460856	DNA topoisomerase I [Cronobacter sakazakii].	25.32	470	281	18	1	446	199	622	3e-14	85.9
rs:WP_023211986	DNA topoisomerase I subunit omega [Salmonella enterica].	26.33	376	234	12	77	446	284	622	3e-14	85.9
rs:WP_041306969	DNA topoisomerase I, partial [Herpetosiphon aurantiacus].	27.25	411	237	13	69	452	257	632	3e-14	85.5
rs:WP_001701436	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	26.33	376	234	12	77	446	198	536	3e-14	85.5
tr:U1MJ04_9EURY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.30	417	261	13	59	453	266	641	3e-14	85.5
rs:WP_044344627	hypothetical protein, partial [Pseudomonas meliae].	25.77	388	227	17	77	446	246	590	3e-14	85.5
rs:WP_044144925	DNA topoisomerase I, partial [Salmonella enterica].	26.33	376	234	12	77	446	284	622	3e-14	85.9
rs:WP_033218470	DNA topoisomerase I [Kitasatospora phosalacinea].	25.73	342	195	13	37	354	252	558	3e-14	85.9
rs:WP_016505322	DNA topoisomerase I [Salmonella enterica].	26.33	376	234	12	77	446	284	622	3e-14	85.9
rs:WP_005346800	DNA topoisomerase I [[Eubacterium] hallii].	23.83	428	264	11	47	454	226	611	3e-14	85.5
tr:X7ZZN7_MYCAV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.26	380	232	11	41	399	251	599	3e-14	85.9
rs:WP_039001476	DNA topoisomerase I [Halocynthiibacter sp. PAMC 20958].	25.56	450	238	18	67	454	249	663	3e-14	85.9
rs:WP_000513590	topoisomerase I [Salmonella enterica].	26.33	376	234	12	77	446	284	622	3e-14	85.5
rs:WP_010969164	DNA topoisomerase I [Sinorhizobium meliloti].	24.09	440	269	14	47	452	236	644	3e-14	85.9
rs:WP_027188295	DNA topoisomerase I [Desulfovibrio cuneatus].	25.18	425	257	12	45	452	223	603	3e-14	85.5
rs:WP_007823946	DNA topoisomerase I [Rhizobium sp. CF142].	25.51	439	265	14	47	452	230	639	3e-14	85.5
rs:WP_025083276	DNA topoisomerase I [Lactobacillus fuchuensis].	24.29	424	239	15	60	452	239	611	3e-14	85.5
tr:Q8RPV4_STRSL	SubName: Full=Topoisomerase {ECO:0000313|EMBL:AAL83958.1}; Flags: Fragment;	26.63	199	142	3	189	385	10	206	3e-14	84.0
rs:WP_047621968	DNA topoisomerase I, partial [Salmonella enterica].	26.33	376	234	12	77	446	125	463	3e-14	85.5
rs:WP_042993550	DNA topoisomerase I, partial [Bordetella bronchiseptica].	27.16	324	199	10	36	354	213	504	3e-14	85.1
rs:WP_004387669	topoisomerase I [Cronobacter sakazakii].	25.32	470	281	18	1	446	199	622	3e-14	85.5
rs:WP_019388943	DNA topoisomerase I [Kingella kingae].	25.75	431	262	11	41	452	227	618	3e-14	85.5
rs:WP_008678395	DNA topoisomerase I [Clostridium sp. 7_2_43FAA].	22.65	393	251	9	77	454	254	608	3e-14	85.5
rs:WP_027484108	DNA topoisomerase I [Rhodanobacter sp. OR87].	27.65	358	208	13	45	380	233	561	3e-14	85.5
rs:WP_046624251	DNA topoisomerase I [Neorhizobium galegae].	25.06	439	266	15	47	452	230	638	3e-14	85.5
rs:WP_017507300	DNA topoisomerase I [beta proteobacterium L13].	23.64	478	261	14	50	459	234	675	3e-14	85.5
rs:WP_032981332	DNA topoisomerase I [Cronobacter malonaticus].	25.32	470	281	18	1	446	199	622	3e-14	85.5
rs:WP_008398460	DNA topoisomerase I [Clostridium sp. M62/1].	25.87	433	256	15	48	457	230	620	3e-14	85.5
rs:WP_038052696	DNA topoisomerase I, partial [Thermomonas fusca].	28.35	381	213	15	66	417	254	603	3e-14	85.5
rs:WP_012897826	DNA topoisomerase I [Lactococcus lactis].	22.04	422	263	12	50	452	250	624	3e-14	85.5
rs:WP_021757590	DNA topoisomerase [Chlamydia pecorum].	25.88	398	223	18	77	449	271	621	3e-14	85.5
rs:WP_028503370	DNA topoisomerase I [Microbacterium sp. URHA0036].	28.12	320	175	11	51	356	268	546	3e-14	85.9
tr:Q64CK3_9ARCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.95	414	277	11	46	454	248	624	3e-14	85.5
tr:K8D9X4_CROSK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.32	470	281	18	1	446	197	620	3e-14	85.5
rs:WP_027841323	DNA topoisomerase I [Mastigocoleus testarum].	26.19	336	200	11	77	395	289	593	3e-14	85.5
rs:WP_032261103	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	3e-14	85.5
rs:WP_002952806	DNA topoisomerase 1 [Salmonella enterica].	26.33	376	234	12	77	446	284	622	3e-14	85.5
rs:WP_001391746	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	3e-14	85.5
rs:WP_029061438	DNA topoisomerase I [Labrenzia sp. DG1229].	26.01	419	238	16	70	449	253	638	3e-14	85.5
rs:WP_043553820	DNA topoisomerase I, partial [Acetobacter malorum].	23.73	434	264	16	38	458	214	593	3e-14	85.1
rs:WP_041596475	DNA topoisomerase I, partial [Halothece sp. PCC 7418].	26.33	357	227	9	32	379	237	566	3e-14	85.5
rs:XP_010320982	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Solanum lycopersicum].	23.88	469	284	16	18	452	246	675	3e-14	85.5
rs:WP_026120863	DNA topoisomerase I [Nocardiopsis potens].	28.08	317	184	11	77	379	311	597	3e-14	85.5
tr:A0A0E3Z163_9GAMM	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:AKC86504.1};	29.57	301	166	11	66	350	254	524	3e-14	85.5
rs:WP_005865502	DNA topoisomerase I [Bartonella alsatica].	27.53	425	233	19	67	452	248	636	3e-14	85.5
rs:WP_009022464	topoisomerase I [gamma proteobacterium NOR5-3].	26.15	390	239	13	74	452	292	643	3e-14	85.5
rs:WP_046093242	DNA topoisomerase I [Salmonella enterica].	26.33	376	234	12	77	446	284	622	3e-14	85.5
tr:G5M307_SALET	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	26.33	376	234	12	77	446	96	434	3e-14	85.5
rs:WP_021915113	GTP-sensing transcriptional pleiotropic repressor CodY [Firmicutes bacterium CAG:24].	24.37	398	244	11	74	454	253	610	3e-14	85.5
rs:WP_044115431	DNA topoisomerase I [Porphyromonas sp. KLE 1280].	27.27	297	183	7	40	334	214	479	3e-14	85.5
rs:WP_025479035	hypothetical protein [Enterococcus faecium].	33.14	172	99	6	67	232	2	163	3e-14	80.9
rs:WP_042439529	DNA topoisomerase I, partial [Sanguibacter keddieii].	26.88	346	197	9	42	356	256	576	3e-14	85.5
rs:WP_007227656	topoisomerase I [marine gamma proteobacterium HTCC2148].	24.47	425	264	13	43	452	262	644	3e-14	85.5
rs:WP_007060088	DNA topoisomerase I [Clostridium carboxidivorans].	25.49	459	248	17	47	449	226	646	3e-14	85.5
rs:WP_029939487	DNA topoisomerase I [Thiomicrospira sp. MA2-6].	26.87	294	170	8	47	334	223	477	3e-14	85.5
rs:WP_026098772	DNA topoisomerase I [Oscillatoria sp. PCC 10802].	24.87	394	243	13	30	401	235	597	3e-14	85.5
rs:WP_023913525	DNA topoisomerase I [Rhodobacter capsulatus].	25.58	430	264	13	47	454	228	623	3e-14	85.5
rs:WP_023246917	DNA topoisomerase I subunit omega [Salmonella enterica].	26.33	376	234	12	77	446	284	622	3e-14	85.5
rs:WP_006201781	DNA topoisomerase I [Mesorhizobium amorphae].	25.17	449	262	18	41	452	224	635	3e-14	85.5
rs:WP_035847622	DNA topoisomerase I [Kitasatospora azatica].	27.21	294	163	12	77	354	300	558	3e-14	85.5
rs:WP_039382418	DNA topoisomerase I [Mycobacterium setense].	27.81	356	203	13	77	410	303	626	3e-14	85.5
rs:WP_006518469	DNA topoisomerase I [Leptolyngbya sp. PCC 7375].	26.88	346	218	9	41	379	249	566	3e-14	85.5
rs:WP_048400759	DNA topoisomerase I [Candidatus Achromatium palustre].	25.53	427	264	16	44	452	230	620	3e-14	85.5
rs:WP_046169030	DNA topoisomerase I [Devosia psychrophila].	27.68	419	243	16	60	452	243	627	3e-14	85.5
rs:WP_014710835	MULTISPECIES: DNA topoisomerase I [Mycobacterium].	25.53	380	231	11	41	399	271	619	3e-14	85.5
rs:WP_022702956	DNA topoisomerase I [Pseudorhodobacter ferrugineus].	26.23	469	246	17	47	454	229	658	3e-14	85.5
rs:WP_019601517	topoisomerase I [Teredinibacter turnerae].	25.36	422	265	13	42	452	261	643	3e-14	85.5
rs:WP_016520265	DNA topoisomerase I [Treponema socranskii].	23.09	433	267	14	41	452	231	618	3e-14	85.5
rs:WP_042427852	DNA topoisomerase I [Streptacidiphilus anmyonensis].	26.06	353	215	12	42	379	275	596	3e-14	85.5
gp:CP002608_247	DNA topoisomerase [Chlamydophila pecorum E58]	25.88	398	223	18	77	449	278	628	3e-14	85.5
rs:WP_022962362	topoisomerase I [Pseudomonas pelagia].	25.32	391	241	14	65	446	278	626	3e-14	85.5
tr:E8R4T3_ISOPI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.24	469	255	15	45	453	350	773	3e-14	85.5
rs:WP_045715043	DNA topoisomerase I, partial [Salmonella enterica].	26.33	376	234	12	77	446	184	522	3e-14	85.5
rs:WP_044593861	DNA topoisomerase I [Cronobacter sakazakii].	25.32	470	281	18	1	446	199	622	3e-14	85.5
rs:WP_032992965	DNA topoisomerase I [Cronobacter malonaticus].	25.32	470	281	18	1	446	199	622	3e-14	85.5
rs:WP_027316167	DNA topoisomerase I [Microvirga flocculans].	25.22	456	256	17	34	452	227	634	3e-14	85.5
rs:WP_023375566	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	26.33	376	234	12	77	446	134	472	3e-14	85.5
rs:WP_022037788	DNA topoisomerase [Ruminococcus gnavus CAG:126].	24.00	425	271	12	48	457	227	614	3e-14	85.5
rs:WP_008263435	DNA topoisomerase I subunit omega [Mycobacterium sp. H4Y].	25.26	380	232	11	41	399	271	619	3e-14	85.5
tr:K8C0K8_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.32	470	281	18	1	446	213	636	3e-14	85.5
rs:WP_032983347	MULTISPECIES: DNA topoisomerase I [Cronobacter].	25.32	470	281	18	1	446	199	622	3e-14	85.5
rs:WP_001649179	DNA topoisomerase I [Salmonella enterica].	26.33	376	234	12	77	446	284	622	3e-14	85.5
rs:WP_023234051	DNA topoisomerase I subunit omega [Salmonella enterica].	26.33	376	234	12	77	446	284	622	3e-14	85.5
tr:R6D1I7_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.71	315	185	8	36	334	201	482	3e-14	85.5
rs:WP_022976701	DNA topoisomerase I [Nevskia ramosa].	28.03	371	204	14	77	417	264	601	3e-14	85.5
rs:WP_005032880	topoisomerase I [Shigella dysenteriae].	26.06	376	235	12	77	446	284	622	3e-14	85.5
rs:WP_023647218	DNA topoisomerase I [actinobacterium LLX17].	28.08	349	209	13	42	377	252	571	3e-14	85.5
tr:T1JEW7_STRMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.88	434	260	17	40	453	261	648	3e-14	85.5
tr:B1II68_CLOBK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.43	431	240	14	74	449	256	651	3e-14	85.5
rs:WP_047319885	DNA topoisomerase I [Mycobacterium heraklionense].	26.80	388	226	12	38	399	268	623	3e-14	85.5
rs:WP_006966437	DNA topoisomerase 1 [Desulfotignum phosphitoxidans].	24.65	426	259	13	47	452	225	608	3e-14	85.5
rs:WP_024843173	DNA topoisomerase I [Paracoccus pantotrophus].	25.87	429	257	16	51	454	233	625	3e-14	85.5
tr:A0A078AUV1_STYLE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.68	463	286	14	28	458	53	475	3e-14	85.1
rs:WP_033039332	DNA topoisomerase I [Pseudoalteromonas sp. S3431].	25.73	377	226	12	36	395	251	590	3e-14	85.5
tr:A9AYY1_HERA2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.25	411	237	13	69	452	257	632	3e-14	85.5
tr:R2W3D4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.58	213	139	4	54	263	266	470	3e-14	84.7
rs:WP_042840451	DNA topoisomerase I, partial [Salmonella enterica].	26.33	376	234	12	77	446	80	418	3e-14	85.1
rs:WP_003598643	MULTISPECIES: DNA topoisomerase I [Lactobacillus casei group].	23.61	432	264	11	43	452	223	610	3e-14	85.1
rs:WP_011310523	DNA topoisomerase I [Thiobacillus denitrificans].	22.62	442	271	13	31	454	217	605	3e-14	85.5
rs:WP_014383732	DNA topoisomerase I [Mycobacterium intracellulare].	25.53	380	231	11	41	399	271	619	3e-14	85.5
rs:WP_035011673	DNA topoisomerase I [Corynebacterium jeikeium].	27.08	325	200	11	41	354	265	563	3e-14	85.5
rs:WP_002507864	MULTISPECIES: DNA topoisomerase I [Staphylococcus].	22.92	432	272	14	40	452	217	606	3e-14	85.1
rs:WP_017325221	hypothetical protein [Synechococcus sp. PCC 7336].	26.67	345	220	8	41	379	249	566	3e-14	85.5
gp:CP003312_1799	DNA topoisomerase I [Cronobacter sakazakii ES15]	25.32	470	281	18	1	446	213	636	3e-14	85.5
tr:A6QKL4_ONYPH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.63	419	258	14	47	450	217	588	3e-14	85.1
rs:WP_046300280	DNA topoisomerase I [Mycobacterium sp. UM_Kg27].	27.45	357	204	13	66	399	295	619	3e-14	85.5
rs:WP_032883712	MULTISPECIES: DNA topoisomerase I [Clostridium].	23.65	427	237	15	77	449	256	647	3e-14	85.1
tr:K8D3D3_CROSK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.32	470	281	18	1	446	213	636	3e-14	85.5
rs:WP_023207743	DNA topoisomerase 1 [Salmonella enterica].	26.33	376	234	12	77	446	284	622	3e-14	85.5
rs:WP_021580713	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	3e-14	85.5
rs:XP_010320983	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Solanum lycopersicum].	23.88	469	284	16	18	452	162	591	3e-14	85.5
rs:WP_005292236	DNA topoisomerase I [Corynebacterium jeikeium].	27.08	325	200	11	41	354	265	563	3e-14	85.5
gp:CP011047_2854	DNA topoisomerase I [Cronobacter sakazakii]	25.32	470	281	18	1	446	213	636	3e-14	85.5
tr:A0A0F3AV89_SALET	SubName: Full=DNA topoisomerase I subunit omega {ECO:0000313|EMBL:KJT97679.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KJT97679.1}; Flags: Fragment;	26.33	376	234	12	77	446	26	364	3e-14	85.1
rs:WP_005102351	DNA topoisomerase I [Mycobacterium abscessus].	26.39	379	230	11	41	399	258	607	3e-14	85.5
gp:CP002011_2285	DNA topoisomerase [Clostridium botulinum F str. 230613]	23.43	431	240	14	74	449	256	651	3e-14	85.1
rs:WP_028877668	DNA topoisomerase I [Teredinibacter turnerae].	25.36	422	265	13	42	452	261	643	3e-14	85.5
tr:U1QGR1_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.58	458	278	13	40	454	320	748	3e-14	85.5
rs:WP_015799301	DNA topoisomerase I [Acidimicrobium ferrooxidans].	27.91	344	190	9	35	354	237	546	3e-14	85.5
rs:WP_015817498	topoisomerase I [Teredinibacter turnerae].	25.53	423	266	13	42	452	261	646	3e-14	85.5
rs:WP_022513709	DNA topoisomerase [Dialister sp. CAG:588].	23.97	438	282	15	35	454	242	646	3e-14	85.5
rs:WP_026161421	DNA topoisomerase I [Corynebacterium ciconiae].	25.08	327	201	8	41	351	258	556	3e-14	85.5
rs:WP_016316209	DNA topoisomerase I [Anaerotruncus sp. G3(2012)].	24.88	430	255	15	47	452	233	618	3e-14	85.1
rs:WP_045230664	DNA topoisomerase I [Agrobacterium rubi].	25.50	451	268	15	38	452	220	638	3e-14	85.5
rs:WP_004998368	topoisomerase I [Shigella boydii].	26.06	376	235	12	77	446	284	622	3e-14	85.5
rs:WP_017666344	DNA topoisomerase I [Porphyrobacter sp. AAP82].	25.22	464	281	16	22	452	192	622	3e-14	85.5
rs:WP_022202470	DNA topoisomerase [Clostridium clostridioforme CAG:132].	23.47	426	271	12	48	457	233	619	3e-14	85.1
rs:WP_015666349	DNA topoisomerase I [Bradyrhizobium oligotrophicum].	24.88	426	257	12	60	454	243	636	3e-14	85.5
rs:WP_005064939	DNA topoisomerase I [Mycobacterium abscessus].	26.39	379	230	11	41	399	258	607	3e-14	85.5
rs:WP_012410891	DNA topoisomerase I [Nostoc punctiforme].	26.63	323	192	11	77	387	285	574	3e-14	85.5
rs:WP_044029693	DNA topoisomerase I [Corynebacterium glutamicum].	25.00	340	208	9	31	354	256	564	3e-14	85.5
rs:WP_027404688	DNA topoisomerase I [Aphanizomenon flos-aquae].	24.93	369	235	10	41	395	249	589	3e-14	85.5
rs:WP_025831860	DNA topoisomerase I [Bacteroides stercorirosoris].	26.25	301	182	7	40	334	216	482	3e-14	85.5
tr:V5TZ61_CROSK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.32	470	281	18	1	446	213	636	3e-14	85.5
rs:WP_038860066	DNA topoisomerase I [Cronobacter sakazakii].	25.32	470	281	18	1	446	200	623	3e-14	85.5
rs:WP_033142381	DNA topoisomerase I [Blautia producta].	24.00	425	271	11	48	457	227	614	3e-14	85.1
rs:XP_012226745	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Linepithema humile].	24.50	400	243	12	73	449	340	703	3e-14	85.5
rs:WP_015211400	DNA topoisomerase I [Cylindrospermum stagnale].	26.73	333	202	11	77	395	285	589	3e-14	85.5
rs:WP_042620614	DNA topoisomerase I [Corynebacterium marinum].	24.26	338	215	8	30	354	251	560	3e-14	85.5
rs:WP_012100386	DNA topoisomerase I [Clostridium botulinum].	23.43	431	240	14	74	449	252	647	3e-14	85.1
tr:D1BDU2_SANKS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.88	346	197	9	42	356	256	576	3e-14	85.5
rs:WP_002788527	DNA topoisomerase I [Microcystis aeruginosa].	24.07	378	239	11	41	401	249	595	3e-14	85.5
rs:WP_004991834	topoisomerase I [Shigella boydii].	26.06	376	235	12	77	446	284	622	3e-14	85.5
tr:E1KTZ0_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFL45038.1};	27.09	251	168	6	43	291	244	481	3e-14	84.7
rs:WP_046660009	DNA topoisomerase I, partial [Escherichia coli].	26.06	376	235	12	77	446	284	622	3e-14	85.1
tr:K9YA52_HALP7	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.33	357	227	9	32	379	237	566	3e-14	85.5
rs:WP_035008817	DNA topoisomerase I [Corynebacterium jeikeium].	27.08	325	200	11	41	354	265	563	3e-14	85.5
rs:WP_038542035	DNA topoisomerase I [Neorhizobium galegae].	24.83	439	267	15	47	452	230	638	3e-14	85.5
rs:WP_020976736	DNA topoisomerase I, omega protein I [Salmonella enterica].	26.33	376	234	12	77	446	284	622	3e-14	85.5
rs:WP_044862322	DNA topoisomerase I, partial [Escherichia coli].	26.53	377	232	14	77	446	284	622	3e-14	85.1
rs:WP_022519081	DNA topoisomerase [Roseburia sp. CAG:100].	24.27	445	273	14	28	454	213	611	3e-14	85.1
rs:WP_008701260	DNA topoisomerase III [Fusobacterium nucleatum].	24.28	449	289	17	24	452	211	628	3e-14	85.1
rs:WP_027739698	DNA topoisomerase I [Streptomyces sp. CNT360].	25.62	324	200	10	42	354	273	566	3e-14	85.5
rs:WP_002749183	DNA topoisomerase I [Microcystis aeruginosa].	24.07	378	239	11	41	401	249	595	3e-14	85.5
rs:WP_022068892	DNA topoisomerase [Blautia sp. CAG:257].	23.92	439	275	12	34	454	212	609	3e-14	85.1
rs:WP_044426265	DNA topoisomerase I [Skermanella aerolata].	26.32	475	260	20	25	452	212	643	3e-14	85.5
rs:WP_000513608	DNA topoisomerase I subunit omega, partial [Shigella dysenteriae].	26.06	376	235	12	77	446	284	622	3e-14	85.1
rs:WP_042405939	DNA topoisomerase I, partial [Corynebacterium sp. JCB].	26.55	290	163	9	77	354	4	255	3e-14	85.1
rs:WP_011274238	DNA topoisomerase I [Corynebacterium jeikeium].	27.08	325	200	11	41	354	265	563	3e-14	85.5
rs:WP_010691753	DNA topoisomerase I [Fructobacillus fructosus].	23.61	432	261	11	43	452	244	628	3e-14	85.1
rs:WP_000520425	topoisomerase I [Vibrio cholerae].	27.03	381	224	15	77	446	292	629	3e-14	85.5
rs:WP_032449279	DNA topoisomerase I [Brucella suis].	26.92	416	238	15	70	452	253	635	3e-14	85.5
rs:WP_012165120	DNA topoisomerase I [Acaryochloris marina].	26.06	376	216	14	27	385	219	549	3e-14	85.1
rs:WP_033095677	DNA topoisomerase I [Colwellia psychrerythraea].	24.51	412	263	12	43	446	257	628	3e-14	85.5
rs:WP_024234990	DNA topoisomerase I [Escherichia coli].	26.58	380	228	14	77	446	284	622	3e-14	85.5
rs:WP_001646990	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	3e-14	85.5
rs:WP_020396072	hypothetical protein [Thiothrix disciformis].	27.81	320	197	9	45	356	233	526	3e-14	85.1
rs:WP_029247485	DNA topoisomerase I [Schlesneria paludicola].	27.10	310	190	8	41	344	252	531	4e-14	85.5
rs:WP_029369302	DNA topoisomerase I [Mycobacterium sp. UM_WWY].	26.51	381	227	12	41	399	271	620	4e-14	85.5
rs:WP_002668452	DNA topoisomerase I [Treponema denticola].	24.71	433	270	15	36	452	210	602	4e-14	85.1
tr:D3BRX9_POLPA	RecName: Full=Ribose-phosphate pyrophosphokinase {ECO:0000256|RuleBase:RU004325}; EC=2.7.6.1 {ECO:0000256|RuleBase:RU004325};	24.52	363	226	10	40	396	589	909	4e-14	85.5
rs:WP_027081111	DNA topoisomerase I [Luteimonas mephitis].	29.51	305	165	12	69	354	255	528	4e-14	85.1
tr:W1GKJ1_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.53	377	232	14	77	446	284	622	4e-14	85.1
rs:WP_043134186	hypothetical protein, partial [Paracoccus sp. 4681].	25.11	438	252	15	60	454	241	645	4e-14	85.5
rs:XP_001356254	GA10090 [Drosophila pseudoobscura pseudoobscura].	24.44	446	269	15	37	451	253	661	4e-14	85.5
rs:WP_006100088	DNA topoisomerase I [Coleofasciculus chthonoplastes].	25.42	358	226	9	40	387	248	574	4e-14	85.5
gp:FR773526_2425	DNA topoisomerase I [Clostridium botulinum H04402 065]	23.67	431	239	15	74	449	256	651	4e-14	85.1
rs:WP_036457573	DNA topoisomerase I [Mycobacterium sp. UM_WGJ].	27.45	357	204	13	66	399	289	613	4e-14	85.5
rs:WP_044589223	DNA topoisomerase I [Bradyrhizobium sp. LTSPM299].	25.28	439	269	12	45	454	228	636	4e-14	85.5
rs:WP_039325786	DNA topoisomerase I [Mycobacterium setense].	27.81	356	203	13	77	410	303	626	4e-14	85.5
rs:WP_009955940	DNA topoisomerase I [Mycobacterium intracellulare].	25.26	380	232	11	41	399	271	619	4e-14	85.5
rs:WP_021073552	DNA topoisomerase I [haloarchaeon 3A1_DGR].	22.78	474	267	15	35	454	242	670	4e-14	85.1
rs:WP_007044609	DNA topoisomerase I [Methanotorris formicicus].	25.00	392	237	16	77	453	275	624	4e-14	85.1
rs:WP_002573299	DNA topoisomerase I [[Clostridium] bolteae].	23.24	426	272	12	48	457	233	619	4e-14	85.1
rs:WP_022937729	DNA topoisomerase I [Dielma fastidiosa].	25.58	430	260	13	41	452	219	606	4e-14	85.1
rs:WP_025775846	DNA topoisomerase I, partial [Clostridium botulinum].	23.43	431	240	14	74	449	252	647	4e-14	85.1
rs:WP_020370685	MULTISPECIES: DNA topoisomerase I [Chlamydia].	25.19	405	234	17	69	449	263	622	4e-14	85.1
rs:WP_041926692	DNA topoisomerase I [Clostridium botulinum].	23.67	431	239	15	74	449	252	647	4e-14	85.1
rs:WP_030503757	DNA topoisomerase I [Micromonospora purpureochromogenes].	25.26	388	233	14	42	409	261	611	4e-14	85.5
tr:R3T638_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.00	210	136	4	57	263	269	470	4e-14	84.7
rs:WP_038988904	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
tr:A0A087PJ20_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.73	434	264	16	38	458	214	593	4e-14	85.1
rs:WP_005691979	topoisomerase I [Haemophilus influenzae].	25.59	379	233	14	77	446	290	628	4e-14	85.1
rs:WP_026506230	DNA topoisomerase I [Butyrivibrio sp. NC3005].	24.46	413	251	12	61	454	244	614	4e-14	85.1
rs:WP_037212691	DNA topoisomerase I [Rhizobium sp. YR295].	25.23	440	264	14	47	452	230	638	4e-14	85.1
rs:WP_022310620	DNA topoisomerase [Prevotella sp. CAG:474].	27.92	283	165	9	77	351	252	503	4e-14	85.1
rs:WP_043667574	DNA topoisomerase I [Streptomyces xylophagus].	27.65	293	163	11	77	354	299	557	4e-14	85.1
rs:WP_045015971	DNA topoisomerase I [Agrobacterium arsenijevicii].	25.79	442	259	16	47	452	230	638	4e-14	85.1
rs:WP_032191162	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_040038412	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_001397166	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
tr:G9EXY9_CLOSG	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.65	427	237	15	77	449	260	651	4e-14	85.1
tr:A0A090M290_OSTTA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.05	515	265	20	22	454	283	758	4e-14	85.5
rs:WP_016893440	DNA topoisomerase I [Mycobacterium abscessus].	26.39	379	230	11	41	399	258	607	4e-14	85.1
rs:WP_005065496	DNA topoisomerase I [Mycobacterium abscessus].	26.39	379	230	11	41	399	258	607	4e-14	85.1
tr:T2MI56_HYDVU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.07	355	224	10	40	386	264	584	4e-14	85.1
rs:XP_002584806	conserved hypothetical protein [Uncinocarpus reesii 1704].	24.79	359	217	11	18	358	210	533	4e-14	84.7
rs:WP_012703691	DNA topoisomerase I [Clostridium botulinum].	23.43	431	240	14	74	449	252	647	4e-14	85.1
rs:WP_033066281	DNA topoisomerase I [Clostridium botulinum].	23.43	431	240	14	74	449	252	647	4e-14	85.1
rs:WP_007104511	DNA topoisomerase I [Paraglaciecola polaris].	25.54	419	254	15	42	446	256	630	4e-14	85.1
rs:WP_019063891	DNA topoisomerase I [Streptomyces prunicolor].	27.65	293	163	11	77	354	299	557	4e-14	85.1
rs:WP_008461318	topoisomerase I [Enterobacter sp. Ag1].	26.33	376	234	12	77	446	284	622	4e-14	85.1
rs:WP_043062780	DNA topoisomerase I [Ochrobactrum anthropi].	26.28	430	245	16	60	452	241	635	4e-14	85.1
rs:WP_048462994	DNA topoisomerase I [Methylobacterium aquaticum].	26.81	455	246	18	36	452	229	634	4e-14	85.1
tr:J5H751_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.15	439	281	12	34	457	209	610	4e-14	85.1
rs:WP_036712476	hypothetical protein, partial [Paracoccus sp. 5503].	25.11	438	252	15	60	454	241	645	4e-14	85.1
tr:U4UXV5_DENPD	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ERL95135.1}; Flags: Fragment;	24.85	326	170	9	166	456	275	560	4e-14	85.1
rs:WP_016341720	DNA topoisomerase I subunit omega [Mycobacterium abscessus].	26.39	379	230	11	41	399	258	607	4e-14	85.1
tr:Q0SSB8_CLOPS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.12	434	250	18	47	454	224	608	4e-14	85.1
tr:U7T468_FUSNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.28	449	289	17	24	452	207	624	4e-14	85.1
rs:WP_040181922	DNA topoisomerase I [Phaeobacter sp. S60].	26.29	464	251	21	41	454	225	647	4e-14	85.1
rs:WP_000296755	hypothetical protein, partial [Streptococcus pneumoniae].	26.33	281	156	9	182	452	8	247	4e-14	83.2
rs:WP_041173293	DNA topoisomerase I [Clostridium botulinum].	23.43	431	240	14	74	449	252	647	4e-14	85.1
rs:WP_001661269	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_001460827	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_047086937	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_006924417	DNA topoisomerase I [Bartonella washoensis].	27.06	425	235	18	67	452	248	636	4e-14	85.1
rs:WP_009302711	DNA topoisomerase I [Desulfovibrio sp. 6_1_46AFAA].	22.76	413	279	8	47	452	225	604	4e-14	85.1
rs:WP_022020244	DNA topoisomerase [Bacteroides sp. CAG:661].	28.47	274	147	8	77	340	253	487	4e-14	85.1
rs:WP_043073258	DNA topoisomerase I [Methylobacterium radiotolerans].	26.28	449	242	17	43	452	236	634	4e-14	85.1
rs:WP_024830849	DNA topoisomerase I [Methylobacterium sp. EUR3 AL-11].	26.28	449	242	17	43	452	236	634	4e-14	85.1
rs:WP_001373327	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_039844588	DNA topoisomerase I [Rhizobium gallicum].	25.00	436	264	14	50	452	233	638	4e-14	85.1
rs:WP_027186352	DNA topoisomerase I [Desulfovibrio inopinatus].	24.82	427	253	12	47	452	225	604	4e-14	85.1
tr:A0A0D5ZFV8_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.65	334	215	10	39	368	246	543	4e-14	85.1
tr:G5Q277_SALMO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.33	376	234	12	77	446	284	622	4e-14	85.1
rs:WP_030894263	DNA topoisomerase I [Streptomyces virginiae].	27.30	293	164	11	77	354	298	556	4e-14	85.1
tr:K8DBD0_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.32	470	281	18	1	446	213	636	4e-14	85.1
rs:WP_004804473	hypothetical protein, partial [Eggerthia catenaformis].	31.79	195	122	4	202	396	17	200	4e-14	81.3
rs:WP_005086898	DNA topoisomerase I [Mycobacterium abscessus].	26.39	379	230	11	41	399	258	607	4e-14	85.1
rs:WP_046831272	DNA topoisomerase I [Xanthomonas axonopodis].	24.65	430	264	14	46	459	229	614	4e-14	85.1
rs:WP_044561089	hypothetical protein [Azospirillum sp. B4].	25.57	309	190	10	67	347	296	592	4e-14	85.1
tr:A0A068EXT8_9LEPT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	24.75	396	222	12	76	450	270	610	4e-14	84.7
rs:WP_013473584	DNA topoisomerase I [Micromonospora sp. L5].	25.26	388	233	14	42	409	261	611	4e-14	85.1
rs:WP_006875905	DNA topoisomerase I [Anaerotruncus colihominis].	23.95	430	267	15	43	452	228	617	4e-14	85.1
rs:WP_032253403	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_001614507	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_001574321	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_001481542	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_001468644	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_001427498	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
tr:R2AW14_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.00	210	136	4	57	263	269	470	4e-14	84.3
rs:WP_016891982	DNA topoisomerase I [Mycobacterium abscessus].	26.39	379	230	11	41	399	258	607	4e-14	85.1
rs:WP_038819903	DNA topoisomerase I [Pseudomonas aeruginosa].	24.33	411	246	14	74	459	260	630	4e-14	84.7
rs:WP_021675255	DNA topoisomerase I [Peptostreptococcaceae bacterium oral taxon 113].	23.89	427	233	15	77	450	258	645	4e-14	85.1
rs:WP_014431876	DNA topoisomerase I [Caldilinea aerophila].	27.19	320	190	10	77	385	290	577	4e-14	85.1
rs:WP_039700276	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	26.63	323	189	11	68	377	274	561	4e-14	84.7
rs:WP_022714857	DNA topoisomerase I [Rhizobium mongolense].	25.72	416	246	14	70	452	253	638	4e-14	85.1
rs:WP_030383632	DNA topoisomerase I [Streptomyces sp. NRRL S-241].	25.97	335	199	11	35	354	256	556	4e-14	85.1
rs:WP_038819896	hypothetical protein, partial [Pseudomonas savastanoi].	25.77	388	227	17	77	446	246	590	4e-14	84.7
rs:WP_015218159	DNA topoisomerase I [Cyanobacterium aponinum].	26.20	332	205	9	47	370	255	554	4e-14	85.1
rs:WP_028954508	DNA topoisomerase I [Synechocystis sp. PCC 7509].	24.32	370	222	12	30	386	232	556	4e-14	85.1
rs:WP_029360563	DNA topoisomerase I [Methylobacterium sp. L2-4].	26.28	449	242	17	43	452	236	634	4e-14	85.1
rs:WP_013166327	DNA topoisomerase I [Starkeya novella].	25.28	443	251	17	47	454	240	637	4e-14	85.1
rs:WP_015503574	topoisomerase I - like protein [Pseudomonas aeruginosa].	24.26	408	244	13	77	459	263	630	4e-14	84.7
rs:WP_028345613	DNA topoisomerase I [Bradyrhizobium elkanii].	25.17	441	267	14	45	454	228	636	4e-14	85.1
rs:WP_039538908	DNA topoisomerase I [Ruegeria sp. ANG-R].	25.70	463	258	17	41	454	225	650	4e-14	85.1
rs:WP_039464588	DNA topoisomerase I [Vibrio navarrensis].	25.42	358	220	10	40	386	253	574	4e-14	85.1
rs:WP_026016696	DNA topoisomerase I [Catenovulum agarivorans].	24.57	468	289	16	1	446	203	628	4e-14	85.1
rs:WP_001396571	topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_042390214	DNA topoisomerase I [Streptacidiphilus melanogenes].	27.36	318	185	12	77	379	308	594	4e-14	85.1
rs:WP_010658870	DNA topoisomerase I [Ochrobactrum anthropi].	26.74	430	243	16	60	452	241	635	4e-14	85.1
rs:WP_017208335	DNA topoisomerase I [Mycobacterium abscessus].	26.39	379	230	11	41	399	258	607	4e-14	85.1
rs:WP_045116484	hypothetical protein, partial [Plesiocystis pacifica].	26.59	425	235	20	65	459	322	699	4e-14	85.1
rs:WP_001641657	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_001554983	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:XP_009403000	PREDICTED: DNA topoisomerase 3-alpha [Musa acuminata subsp. malaccensis].	23.08	455	287	13	24	452	255	672	4e-14	85.1
rs:WP_042987746	DNA topoisomerase I [Vibrio cholerae].	26.51	381	226	15	77	446	292	629	4e-14	85.1
rs:WP_012318007	DNA topoisomerase I [Methylobacterium radiotolerans].	26.28	449	242	17	43	452	236	634	4e-14	85.1
rs:WP_001599360	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_001355506	DNA topoisomerase I subunit omega [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_022157133	DNA topoisomerase [Firmicutes bacterium CAG:145].	24.73	461	255	19	47	453	236	658	4e-14	84.7
rs:WP_045018655	DNA topoisomerase I [Rhizobium nepotum].	26.02	442	258	16	47	452	230	638	4e-14	85.1
rs:WP_044325484	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_001663866	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_001592150	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
tr:D6HW37_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.06	376	235	12	77	446	286	624	4e-14	85.1
rs:WP_033077867	DNA topoisomerase I [Thalassotalea sp. ND16A].	25.25	408	261	12	47	446	260	631	4e-14	85.1
rs:WP_043865257	DNA topoisomerase I [Enterobacter aerogenes].	26.84	380	227	15	77	446	287	625	4e-14	85.1
rs:WP_029927305	DNA topoisomerase I [Ochrobactrum sp. UNC390CL2Tsu3S39].	26.28	430	245	16	60	452	241	635	4e-14	85.1
sp:TOP1_ECOLI	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_042145160	DNA topoisomerase I [Pseudoalteromonas sp. '520P1 No. 412'].	25.72	346	210	9	51	384	266	576	4e-14	85.1
rs:WP_045829100	DNA topoisomerase I [Luteibacter yeojuensis].	28.68	380	216	17	49	405	237	584	4e-14	85.1
rs:WP_007749548	DNA topoisomerase I [Cronobacter dublinensis].	26.14	417	238	16	1	388	129	504	4e-14	85.1
rs:WP_044806905	DNA topoisomerase I, partial [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	84.7
rs:WP_004093343	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_032349710	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_001705049	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_001298801	topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_032805444	DNA topoisomerase I [Cronobacter universalis].	25.32	470	281	18	1	446	199	622	4e-14	85.1
rs:WP_005083492	DNA topoisomerase I [Mycobacterium abscessus].	26.39	379	230	11	41	399	258	607	4e-14	85.1
rs:WP_020223114	DNA topoisomerase I [Holdemania massiliensis].	23.98	467	255	14	47	451	225	653	4e-14	84.7
rs:WP_001437935	topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_042373481	DNA topoisomerase I [Streptacidiphilus neutrinimicus].	27.67	318	184	12	77	379	311	597	4e-14	85.1
rs:WP_032179017	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_034167620	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_021576142	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_005092137	MULTISPECIES: DNA topoisomerase I [Mycobacterium].	26.39	379	230	11	41	399	258	607	4e-14	85.1
rs:WP_000681405	DNA topoisomerase I [Helicobacter pylori].	24.53	428	259	16	41	450	218	599	4e-14	84.7
rs:WP_002437344	topoisomerase I [Escherichia hermannii].	26.84	380	227	15	77	446	287	625	4e-14	85.1
rs:XP_009622050	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Nicotiana tomentosiformis].	24.43	438	264	15	18	424	248	649	4e-14	85.1
rs:WP_037502696	DNA topoisomerase I [Sphingobacterium sp. ACCC 05744].	25.90	278	176	7	61	335	234	484	4e-14	85.1
rs:WP_009345264	DNA topoisomerase I [Peptoniphilus sp. oral taxon 836].	21.80	422	280	10	45	454	226	609	4e-14	84.7
rs:XP_003079855	COG0550: Topoisomerase IA (ISS) [Ostreococcus tauri].	25.05	515	265	20	22	454	243	718	4e-14	85.1
rs:WP_029399852	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_045893060	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_001698223	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_001466145	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_033739473	DNA topoisomerase I [Helicobacter pylori].	24.42	430	257	16	41	450	218	599	4e-14	84.7
rs:WP_001421248	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	287	625	4e-14	85.1
rs:WP_029674661	DNA topoisomerase I [Butyrivibrio sp. VCB2006].	25.23	432	250	17	48	454	224	607	4e-14	84.7
rs:WP_033929724	DNA topoisomerase I [Vibrio cholerae].	26.51	381	226	15	77	446	292	629	4e-14	85.1
rs:WP_009643082	DNA topoisomerase, partial [Mogibacterium sp. CM50].	32.40	179	111	3	218	396	4	172	4e-14	80.5
tr:X1LXD9_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S08239 {ECO:0000313|EMBL:GAI23743.1}; Flags: Fragment;	25.95	289	164	9	56	335	2	249	4e-14	82.0
rs:WP_016239518	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_003955190	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_015606150	DNA topoisomerase I [Salmonella enterica].	26.33	376	234	12	77	446	284	622	4e-14	85.1
rs:WP_012246114	DNA topoisomerase I [Renibacterium salmoninarum].	28.01	332	193	13	77	389	296	600	4e-14	85.1
rs:WP_025819229	DNA topoisomerase I [Bacteroides salyersiae].	25.53	329	195	10	40	354	216	508	4e-14	85.1
rs:WP_036171533	DNA topoisomerase I [Lysobacter dokdonensis].	29.04	303	165	11	66	350	254	524	4e-14	85.1
tr:R1YUH1_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.33	174	100	6	65	232	47	210	4e-14	81.3
rs:WP_008488535	topoisomerase I [Idiomarina xiamenensis].	28.24	393	222	18	77	452	290	639	4e-14	85.1
rs:WP_011293207	DNA topoisomerase I [Thermobifida fusca].	25.78	353	220	11	40	379	273	596	4e-14	85.1
rs:WP_030781823	DNA topoisomerase I [Streptomyces lavenduligriseus].	26.02	342	197	12	35	354	250	557	4e-14	85.1
rs:WP_003915304	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_032807398	DNA topoisomerase I [Siccibacter turicensis].	25.32	470	281	18	1	446	199	622	4e-14	85.1
rs:WP_031449654	DNA topoisomerase I [Desulfobacula sp. TS].	24.37	439	267	15	36	452	214	609	4e-14	84.7
rs:WP_005703159	topoisomerase I [Aggregatibacter aphrophilus].	24.80	379	236	15	77	446	290	628	4e-14	85.1
rs:WP_002564492	DNA topoisomerase I [[Clostridium] bolteae].	23.24	426	272	12	48	457	233	619	4e-14	84.7
rs:WP_037169524	DNA topoisomerase I [Rhizobium sp. CF258].	25.23	440	264	14	47	452	230	638	4e-14	85.1
rs:WP_009736670	DNA topoisomerase I [Bradyrhizobiaceae bacterium SG-6C].	26.56	433	242	14	60	454	243	637	4e-14	85.1
rs:WP_012421655	MULTISPECIES: DNA topoisomerase 1 [Shigella].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_001643336	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_000681456	DNA topoisomerase I [Helicobacter pylori].	25.23	428	256	17	41	450	218	599	4e-14	84.7
rs:WP_036586219	DNA topoisomerase I [Ochrobactrum anthropi].	26.74	430	243	16	60	452	241	635	4e-14	85.1
rs:WP_004826339	DNA topoisomerase I [Peptoniphilus lacrimalis].	21.80	422	280	10	45	454	226	609	4e-14	84.7
rs:XP_003763121	PREDICTED: DNA topoisomerase 3-alpha, partial [Sarcophilus harrisii].	24.32	444	269	15	40	455	184	588	4e-14	85.1
rs:WP_047137101	DNA topoisomerase I [Luteimonas sp. FCS-9].	28.76	299	167	11	69	350	255	524	4e-14	85.1
rs:WP_044697417	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_001591966	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	4e-14	85.1
rs:WP_035619653	DNA topoisomerase I [Lachnoanaerobaculum sp. ICM7].	24.15	439	281	12	34	457	214	615	4e-14	84.7
rs:XP_002404156	topoisomerase I, putative [Ixodes scapularis].	23.40	423	278	12	27	434	247	638	4e-14	85.1
rs:XP_008333802	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Cynoglossus semilaevis].	22.45	441	262	16	40	453	263	650	5e-14	84.7
rs:WP_022109808	DNA topoisomerase [Prevotella sp. CAG:604].	26.37	292	179	8	47	334	222	481	5e-14	84.7
tr:A7BKV9_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.27	363	199	14	110	452	20	337	5e-14	84.0
rs:WP_027663457	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	85.1
rs:XP_004071982	PREDICTED: DNA topoisomerase 3-alpha [Oryzias latipes].	22.83	473	277	15	24	456	290	714	5e-14	85.1
rs:WP_001714078	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	85.1
rs:WP_044877604	DNA topoisomerase I [Paenibacillus sp. IHBB 10380].	24.83	431	259	15	50	457	227	615	5e-14	84.7
rs:WP_023392189	DNA topoisomerase I [Abiotrophia defectiva].	23.88	448	267	17	29	452	206	603	5e-14	84.7
rs:WP_012162550	DNA topoisomerase I [Acaryochloris marina].	27.33	311	185	9	77	377	285	564	5e-14	85.1
rs:WP_038871634	DNA topoisomerase I [Cronobacter dublinensis].	26.14	417	238	16	1	388	199	574	5e-14	85.1
rs:WP_001372673	topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	85.1
rs:WP_001703146	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	85.1
rs:WP_012093053	DNA topoisomerase I [Ochrobactrum anthropi].	26.74	430	243	16	60	452	241	635	5e-14	85.1
rs:WP_036441042	DNA topoisomerase I [Mycoplasma hyosynoviae].	23.40	376	221	12	92	449	271	597	5e-14	84.7
rs:WP_037089087	DNA topoisomerase I [Rhizobium sp. H41].	25.68	444	257	16	47	452	230	638	5e-14	85.1
rs:WP_024232160	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	85.1
rs:WP_042203615	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	85.1
rs:WP_004970853	topoisomerase I [Shigella boydii].	26.06	376	235	12	77	446	284	622	5e-14	85.1
rs:WP_007635410	DNA topoisomerase I [Paraglaciecola psychrophila].	26.50	317	193	10	71	380	284	567	5e-14	85.1
tr:G3VJM6_SARHA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.43	442	271	15	40	455	191	595	5e-14	85.1
rs:WP_005117044	topoisomerase I [Shigella flexneri].	26.06	376	235	12	77	446	284	622	5e-14	85.1
rs:WP_026852069	hypothetical protein [Geothrix fermentans].	24.32	440	275	14	36	446	218	628	5e-14	84.7
rs:WP_044169489	DNA topoisomerase I [Porphyromonas catoniae].	28.08	260	154	6	77	334	251	479	5e-14	84.7
tr:K8B7C3_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.32	470	281	18	1	446	213	636	5e-14	85.1
rs:WP_015741453	topoisomerase I [Siccibacter turicensis].	25.94	374	219	12	1	356	199	532	5e-14	85.1
rs:WP_045149545	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	85.1
rs:WP_047596462	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	85.1
rs:WP_011524140	DNA topoisomerase [Candidatus Koribacter versatilis].	26.47	408	228	16	69	446	256	621	5e-14	85.1
rs:WP_017746750	DNA topoisomerase I [Scytonema hofmanni].	23.15	406	256	11	40	429	257	622	5e-14	84.7
rs:WP_018891896	DNA topoisomerase I [Streptomyces sp. CNT302].	26.01	323	200	9	42	354	276	569	5e-14	85.1
rs:WP_042049273	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	85.1
rs:WP_043953492	DNA topoisomerase I [Enterobacter sp. YD4].	26.02	442	270	17	16	446	227	622	5e-14	85.1
rs:WP_021537199	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	85.1
rs:WP_046640933	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	85.1
rs:WP_021584229	DNA topoisomerase I [Prevotella pleuritidis].	26.54	260	161	7	77	334	252	483	5e-14	84.7
rs:WP_022276224	DNA topoisomerase [Bacteroides finegoldii CAG:203].	27.15	291	178	8	47	334	223	482	5e-14	84.7
rs:WP_020172467	DNA topoisomerase I [Gordonia polyisoprenivorans].	25.87	402	245	14	41	424	270	636	5e-14	85.1
rs:WP_035217622	DNA topoisomerase I [Agrobacterium tumefaciens].	25.51	443	259	16	47	452	230	638	5e-14	85.1
rs:WP_024262211	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_038883495	DNA topoisomerase I [Cronobacter dublinensis].	26.14	417	238	16	1	388	199	574	5e-14	84.7
rs:WP_012674102	DNA topoisomerase I [Sulfurihydrogenibium azorense].	23.44	401	254	12	2	385	172	536	5e-14	84.7
rs:WP_001704495	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_001433303	topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_034353657	DNA topoisomerase I [Helicobacter sp. MIT 09-6949].	24.88	434	262	15	41	454	221	610	5e-14	84.7
rs:WP_046667740	DNA topoisomerase I [Neorhizobium galegae].	25.06	439	266	15	47	452	230	638	5e-14	85.1
tr:H2MFK0_ORYLA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.83	473	277	15	24	456	240	664	5e-14	85.1
rs:WP_032352450	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_045177202	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_018428142	DNA topoisomerase I [Hoeflea sp. 108].	24.43	438	265	16	45	449	228	632	5e-14	84.7
tr:A6G953_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.59	425	235	20	65	459	336	713	5e-14	84.7
rs:WP_001681014	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_033808261	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_022332091	DNA topoisomerase [Alistipes sp. CAG:29].	24.60	309	189	7	40	340	214	486	5e-14	84.7
rs:WP_027581240	DNA topoisomerase I [Bradyrhizobium sp. Ai1a-2].	24.32	444	267	14	45	454	228	636	5e-14	85.1
rs:WP_001342100	MULTISPECIES: topoisomerase I [Enterobacteriaceae].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_001707026	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_012756988	DNA topoisomerase I [Rhizobium leguminosarum].	25.06	439	266	15	47	452	230	638	5e-14	84.7
rs:WP_031006534	DNA topoisomerase I [Streptomyces sp. NRRL F-5727].	25.88	340	196	12	37	354	252	557	5e-14	85.1
rs:WP_022135741	DNA topoisomerase [Firmicutes bacterium CAG:176].	24.94	437	272	14	43	459	223	623	5e-14	84.7
tr:D2ADR0_SHIF2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.06	376	235	12	77	446	298	636	5e-14	84.7
tr:F4VBV2_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.06	376	235	12	77	446	298	636	5e-14	84.7
rs:WP_047740450	DNA topoisomerase I [Enterobacter cloacae].	26.34	391	232	15	77	452	284	633	5e-14	84.7
rs:WP_016525066	DNA topoisomerase I [Treponema maltophilum].	23.35	424	259	15	50	452	233	611	5e-14	84.7
tr:W1B3B9_KLEPN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.06	376	235	12	77	446	200	538	5e-14	84.7
rs:WP_022104140	DNA topoisomerase [Bacteroides stercoris CAG:120].	26.25	301	182	7	40	334	216	482	5e-14	84.7
rs:WP_021991100	DNA topoisomerase [Prevotella sp. CAG:1092].	26.41	337	209	10	27	360	214	514	5e-14	84.7
rs:WP_001541847	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_039064846	DNA topoisomerase I [Shigella flexneri].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_021570479	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
tr:T0PKA2_9CLOT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.06	435	249	14	47	454	176	560	5e-14	84.7
rs:WP_042108431	DNA topoisomerase I, partial [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_005899117	DNA topoisomerase I subunit omega [Aeromonas molluscorum].	25.12	426	263	13	42	452	252	636	5e-14	84.7
rs:WP_008936803	MULTISPECIES: DNA topoisomerase I [Brucella].	26.68	416	239	15	70	452	253	635	5e-14	84.7
rs:WP_006372355	DNA topoisomerase I [Gordonia polyisoprenivorans].	25.87	402	245	14	41	424	270	636	5e-14	85.1
rs:WP_009839581	topoisomerase I [Pseudoalteromonas tunicata].	25.67	409	252	14	49	446	265	632	5e-14	84.7
rs:WP_044778602	DNA topoisomerase I [Campylobacter jejuni].	25.35	426	246	17	47	450	225	600	5e-14	84.7
rs:XP_011194795	PREDICTED: DNA topoisomerase 3-alpha [Bactrocera cucurbitae].	24.83	451	267	16	35	451	276	688	5e-14	85.1
rs:WP_013280745	DNA topoisomerase I [Butyrivibrio proteoclasticus].	22.95	427	266	13	48	454	237	620	5e-14	84.7
rs:WP_017947790	DNA topoisomerase I [Streptomyces sp. CNS615].	26.01	323	200	9	42	354	276	569	5e-14	85.1
rs:WP_047893939	DNA topoisomerase I, partial [Micromonospora sp. RV43].	25.26	388	233	14	42	409	261	611	5e-14	84.7
rs:WP_032221027	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_001428676	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_019841512	topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_001326307	topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_039303632	DNA topoisomerase I [Cedecea neteri].	26.33	376	234	12	77	446	284	622	5e-14	84.7
rs:WP_038862609	DNA topoisomerase I [Cronobacter muytjensii].	24.68	470	284	18	1	446	199	622	5e-14	84.7
rs:WP_001437686	topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_001359511	topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_021518705	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_001559015	DNA topoisomerase 1 [Escherichia coli].	26.10	387	238	13	77	452	284	633	5e-14	84.7
rs:WP_047663626	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_038487602	DNA topoisomerase I [Bartonella henselae].	26.59	425	237	18	67	452	248	636	5e-14	84.7
rs:WP_006275828	DNA topoisomerase I [Cylindrospermopsis raciborskii].	26.27	354	226	9	41	387	249	574	5e-14	84.7
rs:WP_048224219	DNA topoisomerase I, partial [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_016192569	DNA topoisomerase I subunit omega [Erwinia tracheiphila].	26.23	408	235	19	68	452	269	633	5e-14	84.7
rs:WP_024446927	DNA topoisomerase I [Mycobacterium iranicum].	25.90	390	239	13	41	410	268	627	5e-14	84.7
rs:XP_012194243	hypothetical protein SPRG_00629 [Saprolegnia parasitica CBS 223.65].	26.76	355	220	9	39	385	261	583	5e-14	85.1
rs:WP_001382110	topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_034855894	DNA topoisomerase I [Ignatzschineria larvae].	26.17	386	227	14	60	416	245	601	5e-14	84.7
rs:WP_011753872	DNA topoisomerase I [Nocardioides sp. JS614].	29.79	292	161	11	77	356	291	550	5e-14	84.7
rs:WP_024246437	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_021523431	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_043014794	DNA topoisomerase I, partial [Corynebacterium jeikeium].	25.31	324	201	9	41	351	149	444	5e-14	84.7
rs:WP_029108391	DNA topoisomerase I [Mycobacterium sp. URHD0025].	26.06	376	225	12	77	430	303	647	5e-14	84.7
rs:WP_026172433	hypothetical protein, partial [euryarchaeote SCGC AAA261-G15].	23.21	405	249	14	47	436	239	596	5e-14	84.7
rs:WP_010441666	DNA topoisomerase I [Ruegeria conchae].	25.86	464	257	17	41	454	225	651	5e-14	84.7
rs:WP_001383172	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_001593985	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_005062053	topoisomerase I [Shigella flexneri].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_012143178	topoisomerase I [Shewanella sediminis].	26.15	348	206	12	57	388	271	583	5e-14	84.7
tr:K8AMF9_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.14	417	238	16	1	388	213	588	5e-14	84.7
rs:WP_002597513	DNA topoisomerase I [Clostridium colicanis].	24.69	401	239	14	74	454	250	607	5e-14	84.7
rs:WP_038887553	DNA topoisomerase I [Cronobacter dublinensis].	26.14	417	238	16	1	388	199	574	5e-14	84.7
rs:WP_021518134	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_001506205	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_001484536	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_035400416	DNA topoisomerase I [Faecalitalea cylindroides].	23.83	407	235	13	75	455	253	610	5e-14	84.7
rs:WP_018364712	DNA topoisomerase I [Streptococcus caballi].	22.61	429	271	12	40	452	243	626	5e-14	84.7
rs:WP_000513603	DNA topoisomerase I subunit omega, partial [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_014639162	topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_047605417	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_043635602	DNA topoisomerase I [Chromobacterium haemolyticum].	22.92	480	264	14	49	459	233	675	5e-14	84.7
rs:XP_011347623	PREDICTED: DNA topoisomerase 3-alpha [Cerapachys biroi].	24.46	417	247	13	60	449	277	652	5e-14	84.7
tr:Q0T5C5_SHIF8	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.06	376	235	12	77	446	298	636	5e-14	84.7
rs:WP_037069412	DNA topoisomerase I [Pseudonocardia acaciae].	26.38	326	198	10	42	354	300	596	5e-14	84.7
rs:WP_001684861	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_001526939	MULTISPECIES: DNA topoisomerase 1 [Enterobacteriaceae].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_001309471	MULTISPECIES: DNA topoisomerase I [Enterobacteriaceae].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_001485714	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_022296446	DNA topoisomerase [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_036363021	DNA topoisomerase I [Mycobacterium asiaticum].	25.53	380	231	11	41	399	268	616	5e-14	84.7
tr:A0A026VYF1_CERBI	SubName: Full=DNA topoisomerase 3-alpha {ECO:0000313|EMBL:EZA48833.1};	24.70	417	246	14	60	449	111	486	5e-14	84.7
rs:XP_006749735	PREDICTED: DNA topoisomerase 3-alpha [Leptonychotes weddellii].	26.00	400	222	16	90	455	283	642	5e-14	84.7
rs:WP_001385318	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_001295576	MULTISPECIES: DNA topoisomerase I [Enterobacteriaceae].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:XP_008333800	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Cynoglossus semilaevis].	22.22	441	263	15	40	453	263	650	5e-14	84.7
tr:F4SWU8_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.06	376	235	12	77	446	306	644	5e-14	84.7
rs:WP_020012348	MULTISPECIES: DNA topoisomerase I [Agrobacterium].	25.51	443	259	16	47	452	230	638	5e-14	84.7
rs:WP_036471856	DNA topoisomerase I [Mycobacterium triplex].	25.26	380	232	11	41	399	270	618	5e-14	84.7
rs:WP_032257049	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_001607265	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_044794031	DNA topoisomerase I [Campylobacter jejuni].	25.00	432	252	17	41	450	219	600	5e-14	84.7
gpu:CP011489_224	DNA topoisomerase I, bacterial [Actinobacteria bacterium IMCC26256]	30.31	320	176	14	37	342	238	524	5e-14	84.7
rs:WP_027733727	DNA topoisomerase I [Streptomyces sp. CNR698].	26.01	323	200	9	42	354	276	569	5e-14	84.7
rs:WP_014136690	DNA topoisomerase I [Kitasatospora setae].	25.53	329	194	12	42	354	265	558	5e-14	84.7
rs:WP_023984273	DNA topoisomerase I [Prevotella oralis].	25.89	336	213	10	4	334	179	483	5e-14	84.7
rs:WP_044702697	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_001360019	topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_047085249	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_005068394	topoisomerase I [Shigella flexneri].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:XP_010270299	PREDICTED: DNA topoisomerase 3-alpha [Nelumbo nucifera].	23.86	440	275	13	39	452	266	671	5e-14	84.7
rs:WP_047996125	DNA topoisomerase I [Puniceibacterium sp. IMCC21224].	25.90	471	256	17	41	454	225	659	5e-14	84.7
rs:WP_035857273	DNA topoisomerase I [Jeotgalicoccus marinus].	24.54	432	263	16	40	452	218	605	5e-14	84.3
rs:WP_045894874	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_020240018	topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_016234290	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_028131801	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_028126135	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_001682840	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_022448738	DNA topoisomerase [Roseburia sp. CAG:303].	24.12	427	262	12	48	454	227	611	5e-14	84.3
rs:WP_016553640	DNA topoisomerase I subunit omega [Rhizobium grahamii].	25.28	439	265	15	47	452	230	638	5e-14	84.7
rs:WP_031841775	hypothetical protein [Vibrio parahaemolyticus].	32.65	147	98	1	257	402	11	157	5e-14	80.1
rs:WP_011314971	DNA topoisomerase I [Nitrobacter winogradskyi].	24.72	441	269	13	45	454	228	636	5e-14	84.7
rs:WP_039020811	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_001353238	MULTISPECIES: topoisomerase I [Escherichia].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_032292753	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_024212192	DNA topoisomerase I [Escherichia sp. TW15838].	26.06	376	235	12	77	446	284	622	5e-14	84.7
rs:WP_017384217	MULTISPECIES: topoisomerase I [Enterobacter cloacae complex].	26.32	380	229	14	77	446	284	622	5e-14	84.7
rs:WP_026313436	DNA topoisomerase I [Actinomadura flavalba].	23.97	363	226	11	42	387	268	597	6e-14	84.7
rs:WP_032077656	DNA topoisomerase I [Clostridium drakei].	25.05	455	255	15	47	449	226	646	6e-14	84.3
rs:WP_013283654	MULTISPECIES: DNA topoisomerase I [Micromonospora].	25.26	388	233	14	42	409	261	611	6e-14	84.7
tr:E5B5W3_ERWAM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.09	391	233	15	77	452	284	633	6e-14	84.7
rs:WP_036391367	DNA topoisomerase I [Mycobacterium farcinogenes].	27.53	356	204	13	77	410	303	626	6e-14	84.7
rs:WP_036580980	DNA topoisomerase I, partial [Ochrobactrum anthropi].	26.74	430	243	16	60	452	45	439	6e-14	84.3
tr:A0A0A0F9H1_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.06	376	235	12	77	446	298	636	6e-14	84.7
rs:WP_032169931	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_005049701	topoisomerase I [Shigella flexneri].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_001484824	topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_023145287	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_001538694	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_005087983	topoisomerase I [Shigella flexneri].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_044508780	DNA topoisomerase I [Mycobacterium simiae].	25.26	384	231	11	41	399	270	622	6e-14	84.7
rs:WP_009496920	DNA topoisomerase I [Campylobacter showae].	24.88	422	253	15	47	450	224	599	6e-14	84.3
rs:WP_021848783	DNA topoisomerase [Bacteroides sp. CAG:598].	28.52	270	152	8	77	340	253	487	6e-14	84.7
rs:WP_001339670	MULTISPECIES: topoisomerase I [Enterobacteriaceae].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_024880185	DNA topoisomerase I [Methylosinus sp. LW3].	25.47	428	248	13	60	452	243	634	6e-14	84.7
rs:WP_029161493	DNA topoisomerase I [Clostridium scatologenes].	25.05	455	255	15	47	449	226	646	6e-14	84.3
rs:XP_002307047	hypothetical protein POPTR_0005s06810g [Populus trichocarpa].	23.72	468	285	13	18	451	236	665	6e-14	84.7
rs:WP_044721998	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_046426265	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_001304419	MULTISPECIES: DNA topoisomerase I [Enterobacteriaceae].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_032084999	DNA topoisomerase I, partial [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_011412723	topoisomerase I [Aster yellows witches'-broom phytoplasma].	23.08	442	258	15	47	457	217	607	6e-14	84.3
rs:WP_047091085	DNA topoisomerase I, partial [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_001337939	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_004157737	topoisomerase I [Erwinia amylovora].	26.09	391	233	15	77	452	284	633	6e-14	84.7
rs:WP_045345096	DNA topoisomerase I [Enterobacter cloacae].	26.32	380	229	14	77	446	284	622	6e-14	84.7
rs:WP_021516023	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_001560478	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_005817708	topoisomerase I [Actinobacillus minor].	25.79	380	231	15	77	446	290	628	6e-14	84.7
rs:WP_024262109	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_031935302	DNA topoisomerase I, partial [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_046314796	DNA topoisomerase I [Mycobacterium sp. UM_Kg1].	27.17	357	205	13	66	399	292	616	6e-14	84.7
rs:WP_033550377	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_014073449	DNA topoisomerase I [Lactobacillus ruminis].	22.82	425	244	16	57	452	228	597	6e-14	84.3
rs:WP_027662585	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_000513601	topoisomerase I [Escherichia fergusonii].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_033865378	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_001382542	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_018021499	DNA topoisomerase I [Corynebacterium doosanense].	25.63	359	218	14	36	378	258	583	6e-14	84.7
tr:D6J9Q0_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.06	376	235	12	77	446	286	624	6e-14	84.7
rs:WP_005091745	topoisomerase I [Shigella flexneri].	26.06	376	235	12	77	446	284	622	6e-14	84.7
tr:F4TDH0_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.06	376	235	12	77	446	298	636	6e-14	84.7
rs:WP_013337555	DNA topoisomerase [Vulcanisaeta distributa].	23.33	420	234	13	32	410	244	616	6e-14	84.3
rs:WP_039270612	DNA topoisomerase I [Enterobacter cloacae].	26.32	380	229	14	77	446	284	622	6e-14	84.7
rs:WP_014358786	DNA topoisomerase I [Gordonia polyisoprenivorans].	25.87	402	245	14	41	424	270	636	6e-14	84.7
rs:WP_009248640	DNA topoisomerase I [Lachnospiraceae bacterium 5_1_57FAA].	23.91	414	262	10	60	457	239	615	6e-14	84.3
rs:WP_001252809	topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	298	636	6e-14	84.7
rs:WP_033552514	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_044864065	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_027338521	DNA topoisomerase I [Helicobacter bilis].	22.72	427	268	13	41	450	222	603	6e-14	84.3
rs:WP_035316934	DNA topoisomerase I [Clostridium sp. MSTE9].	25.29	435	261	17	40	452	227	619	6e-14	84.3
rs:WP_019618173	hypothetical protein [Pseudoclavibacter faecalis].	25.93	297	175	8	77	354	284	554	6e-14	84.7
rs:WP_035799481	DNA topoisomerase I [Cyanothece sp. CCY0110].	25.06	427	234	16	40	436	241	611	6e-14	84.3
rs:WP_038585743	DNA topoisomerase I [Neorhizobium galegae].	24.83	439	267	15	47	452	230	638	6e-14	84.7
rs:WP_046600125	DNA topoisomerase I [Neorhizobium galegae].	24.83	439	267	15	47	452	230	638	6e-14	84.7
rs:XP_002641457	C. briggsae CBR-TOP-3 protein, partial [Caenorhabditis briggsae].	26.70	367	220	13	39	392	260	590	6e-14	84.3
rs:WP_022394748	DNA topoisomerase [Coprobacillus sp. CAG:826].	24.56	395	229	13	77	450	253	599	6e-14	84.3
rs:WP_019792391	hypothetical protein [Streptococcus sobrinus].	25.59	340	208	11	71	403	276	577	6e-14	84.3
gp:CP003182_2455	DNA topoisomerase I [Granulibacter bethesdensis CGDNIH4]	25.11	454	270	16	31	452	232	647	6e-14	84.7
rs:WP_012601486	topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_035147206	DNA topoisomerase III, partial [Lactobacillus sakei].	27.71	231	136	2	159	389	1	200	6e-14	82.4
tr:K8AML0_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.68	470	284	18	1	446	213	636	6e-14	84.7
rs:WP_001619376	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_001362355	topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_001518579	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:XP_007247892	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Astyanax mexicanus].	23.28	451	268	14	39	455	287	693	6e-14	84.7
rs:WP_029523172	DNA topoisomerase I [Persephonella sp. KM09-Lau-8].	23.82	361	222	10	40	385	216	538	6e-14	84.3
rs:WP_008778583	DNA topoisomerase III [Parabacteroides sp. 20_3].	26.28	331	208	9	61	385	262	562	6e-14	84.3
rs:WP_018226836	DNA topoisomerase I [actinobacterium SCGC AAA023-D18].	26.07	326	199	9	41	354	248	543	6e-14	84.7
rs:WP_021071562	DNA topoisomerase I [Sphingobacterium paucimobilis].	25.90	278	174	6	61	334	234	483	6e-14	84.3
rs:WP_001366271	MULTISPECIES: topoisomerase I [Enterobacteriaceae].	26.06	376	235	12	77	446	284	622	6e-14	84.7
tr:A0A0C3PNK5_PISTI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.46	377	227	12	46	404	261	601	6e-14	84.7
rs:WP_012729597	topoisomerase I [Tolumonas auensis].	25.83	391	232	14	77	452	288	635	6e-14	84.7
rs:WP_022410775	DNA topoisomerase [Ruminococcus sp. CAG:330].	26.00	400	227	17	77	452	14	368	6e-14	83.6
rs:WP_016424904	DNA topoisomerase 1 [Staphylococcus sp. HGB0015].	23.49	430	263	15	43	452	223	606	6e-14	84.3
rs:WP_024259893	DNA topoisomerase I [Shigella flexneri].	26.06	376	235	12	77	446	284	622	6e-14	84.7
rs:WP_011935078	DNA topoisomerase I [Synechococcus sp. RCC307].	25.53	376	228	13	40	398	249	589	6e-14	84.7
rs:WP_048449025	DNA topoisomerase I [Methylobacterium tarhaniae].	26.40	447	244	16	43	452	236	634	6e-14	84.7
rs:WP_045152100	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	281	619	6e-14	84.3
rs:WP_045433809	DNA topoisomerase I [Mycoplasma canadense].	24.40	373	218	11	92	450	271	593	6e-14	84.3
rs:WP_025320889	DNA topoisomerase I [Granulibacter bethesdensis].	25.11	454	270	16	31	452	221	636	6e-14	84.7
rs:WP_009064086	DNA topoisomerase I [Clostridium sp. JCD].	25.40	433	259	17	40	450	218	608	6e-14	84.3
tr:A0A034U040_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAJ77702.1};	41.00	100	59	0	293	392	1	100	6e-14	78.2
tr:A0A0A2V3B3_BEABA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	35.84	173	94	6	38	199	252	418	6e-14	83.6
rs:WP_046203271	DNA topoisomerase I [Corynebacterium kroppenstedtii].	24.32	366	229	9	31	378	268	603	6e-14	84.7
rs:WP_032297743	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	6e-14	84.3
tr:A0A091NLP0_APAVI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.77	423	241	17	60	456	296	671	6e-14	84.7
rs:WP_012610322	DNA topoisomerase I [Desulfatibacillum alkenivorans].	23.97	484	291	19	1	452	170	608	6e-14	84.3
rs:WP_020971805	DNA topoisomerase I [Helicobacter pylori].	24.53	428	259	16	41	450	218	599	6e-14	84.3
rs:WP_046636596	DNA topoisomerase I [Neorhizobium galegae].	25.06	439	266	15	47	452	230	638	6e-14	84.3
rs:WP_043615263	DNA topoisomerase I [Nonomuraea candida].	28.53	354	188	15	39	374	259	565	6e-14	84.3
rs:WP_035044009	DNA topoisomerase I [Caulobacter henricii].	25.47	424	247	14	61	452	243	629	6e-14	84.3
rs:WP_022084261	DNA topoisomerase, partial [Mycoplasma sp. CAG:611].	26.06	353	209	11	106	449	16	325	6e-14	83.2
rs:WP_011676299	DNA topoisomerase I [Lactococcus lactis].	21.80	422	264	12	50	452	248	622	6e-14	84.3
tr:U2PF89_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.83	407	235	13	75	455	262	619	6e-14	84.3
rs:WP_009469347	DNA topoisomerase I [Roseibium sp. TrichSKD4].	24.70	421	247	14	70	452	253	641	6e-14	84.3
rs:WP_046893610	DNA topoisomerase I [Morganella morganii].	26.01	419	256	17	49	452	251	630	6e-14	84.3
rs:WP_045341511	DNA topoisomerase I [Enterobacter cloacae].	26.32	380	229	14	77	446	284	622	7e-14	84.3
rs:WP_001354108	topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	7e-14	84.3
rs:WP_044133343	DNA topoisomerase III, partial [Bacteroides fragilis].	32.32	164	102	5	31	193	253	408	7e-14	83.2
tr:B0NRM5_BACSE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.91	301	183	7	40	334	239	505	7e-14	84.3
rs:WP_034085616	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	24.39	410	247	13	74	459	79	449	7e-14	83.6
rs:WP_001691736	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	7e-14	84.3
rs:WP_008976266	MULTISPECIES: DNA topoisomerase I [Coprococcus].	23.76	425	272	12	48	457	227	614	7e-14	84.3
rs:WP_046647868	DNA topoisomerase I [Corynebacterium minutissimum].	25.75	365	214	14	41	384	253	581	7e-14	84.7
rs:WP_022028557	DNA topoisomerase [Clostridium sp. CAG:1219].	24.30	391	254	11	69	454	246	599	7e-14	84.3
rs:WP_036927214	DNA topoisomerase I [Prevotella timonensis].	26.86	309	193	8	28	334	204	481	7e-14	84.3
rs:WP_023213660	DNA topoisomerase I subunit omega [Salmonella enterica].	26.06	376	235	12	77	446	284	622	7e-14	84.3
rs:WP_023184162	DNA topoisomerase I subunit omega [Salmonella enterica].	26.33	376	234	12	77	446	284	622	7e-14	84.3
rs:WP_038294596	DNA topoisomerase I, partial [alpha proteobacterium SCGC AAA027-C06].	25.06	443	263	14	48	454	231	640	7e-14	84.3
rs:WP_022238987	DNA topoisomerase [Lachnospiraceae bacterium CAG:364].	24.71	429	263	13	48	457	227	614	7e-14	84.3
rs:WP_034968817	DNA topoisomerase I [Corynebacterium jeikeium].	25.31	324	201	9	41	351	265	560	7e-14	84.7
rs:WP_037702547	DNA topoisomerase I [Streptomyces scabiei].	25.50	404	238	14	35	409	250	619	7e-14	84.3
rs:WP_017724285	DNA topoisomerase I [Staphylococcus xylosus].	24.56	395	236	14	77	452	254	605	7e-14	84.3
rs:WP_042394310	DNA topoisomerase I [Escherichia vulneris].	26.58	380	228	15	77	446	284	622	7e-14	84.3
tr:T0L751_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.21	474	314	16	1	452	177	622	7e-14	84.3
tr:T1L4W6_TETUR	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:tetur41g00370.1};	24.73	368	234	10	39	399	292	623	7e-14	84.3
rs:WP_039609901	DNA topoisomerase I [Pseudoalteromonas luteoviolacea].	24.88	414	253	16	48	446	261	631	7e-14	84.3
rs:WP_042067134	DNA topoisomerase I, partial [Escherichia coli].	26.06	376	235	12	77	446	284	622	7e-14	84.3
rs:WP_011975123	DNA topoisomerase I [Sinorhizobium medicae].	23.97	438	272	13	47	452	250	658	7e-14	84.3
rs:WP_036286299	DNA topoisomerase I [Microbacterium sp. MRS-1].	29.35	402	212	18	23	392	234	595	7e-14	84.3
rs:WP_006780289	DNA topoisomerase I [Hungatella hathewayi].	23.95	430	258	11	48	454	230	613	7e-14	84.3
rs:WP_015929895	DNA topoisomerase I [Methylobacterium nodulans].	26.82	425	229	15	68	452	252	634	7e-14	84.3
tr:A0A0A1G0D0_9MYCO	RecName: Full=DNA topoisomerase 1; EC=5.99.1.2; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.25	356	205	13	77	410	267	590	7e-14	84.3
rs:WP_010699175	DNA topoisomerase I [Treponema denticola].	24.37	435	269	15	36	452	232	624	7e-14	84.3
rs:WP_047725966	DNA topoisomerase I [Enterobacter cloacae].	26.32	380	229	14	77	446	284	622	7e-14	84.3
rs:WP_035096835	DNA topoisomerase I [Devosia sp. LC5].	26.38	417	251	14	60	452	243	627	7e-14	84.3
rs:WP_023438149	DNA topoisomerase I, partial [Clostridium tetani].	25.53	380	214	15	98	454	1	334	7e-14	83.6
rs:WP_034993148	DNA topoisomerase I [Corynebacterium jeikeium].	25.31	324	201	9	41	351	265	560	7e-14	84.3
rs:WP_003599338	DNA topoisomerase I [Methylobacterium extorquens].	26.06	449	243	17	43	452	236	634	7e-14	84.3
rs:WP_012254575	DNA topoisomerase I [Methylobacterium extorquens].	26.61	451	238	19	43	452	236	634	7e-14	84.3
rs:WP_022488349	DNA topoisomerase [Acidaminococcus sp. CAG:542].	25.12	430	231	16	77	452	255	647	7e-14	84.3
rs:WP_034452594	DNA topoisomerase I [Butyrivibrio sp. AE2032].	22.93	423	271	11	48	454	224	607	7e-14	84.3
rs:WP_035801076	DNA topoisomerase I [Butyrivibrio sp. FCS014].	24.88	426	259	14	48	454	225	608	7e-14	84.3
rs:WP_035007783	DNA topoisomerase I [Corynebacterium jeikeium].	25.31	324	201	9	41	351	265	560	7e-14	84.3
rs:WP_026960310	DNA topoisomerase I [Aliagarivorans taiwanensis].	25.00	420	268	13	35	446	249	629	7e-14	84.3
rs:WP_008274156	DNA topoisomerase I [Cyanothece sp. CCY0110].	25.35	359	223	11	41	387	249	574	7e-14	84.3
rs:WP_025286316	DNA topoisomerase I [Granulibacter bethesdensis].	25.11	454	270	16	31	452	221	636	7e-14	84.3
rs:WP_037969390	DNA topoisomerase I [Streptosporangium amethystogenes].	26.54	324	197	11	42	354	248	541	7e-14	84.3
rs:WP_018821865	DNA topoisomerase I [Salinispora pacifica].	25.77	326	193	12	42	351	261	553	7e-14	84.3
rs:XP_007048481	Topoisomerase 3alpha isoform 2, partial [Theobroma cacao].	24.15	439	273	14	39	451	264	668	7e-14	84.3
rs:WP_009679427	DNA topoisomerase I [Gordonia neofelifaecis].	26.33	357	214	11	41	379	262	587	7e-14	84.3
rs:WP_016324077	DNA topoisomerase I [Oscillibacter sp. 1-3].	25.23	440	259	15	47	459	228	624	7e-14	84.3
rs:WP_044976306	DNA topoisomerase I [Ruminococcus sp. HUN007].	24.02	433	269	14	41	452	219	612	7e-14	84.3
tr:F7ES60_XENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.01	452	270	18	29	453	251	651	7e-14	84.3
rs:WP_023345728	DNA topoisomerase I [Firmicutes bacterium ASF500].	26.14	440	269	12	34	454	215	617	7e-14	84.3
rs:WP_038334579	DNA topoisomerase I [Kingella kingae].	25.99	431	261	12	41	452	227	618	7e-14	84.3
rs:WP_039107348	hypothetical protein [Lactobacillus brevis].	28.17	284	168	7	60	340	266	516	7e-14	84.3
rs:WP_044197837	DNA topoisomerase I [Hyalangium minutum].	23.49	447	270	14	41	452	295	704	7e-14	84.3
rs:WP_005824022	topoisomerase I [Actinobacillus minor].	25.79	380	231	15	77	446	290	628	7e-14	84.3
rs:WP_015309699	DNA topoisomerase I [Mycobacterium smegmatis].	26.13	375	224	11	47	399	274	617	7e-14	84.3
rs:WP_033979297	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	26.42	318	182	10	166	459	10	299	7e-14	82.0
rs:WP_044979619	DNA topoisomerase I [Treponema putidum].	22.84	464	275	12	36	449	232	662	7e-14	84.3
rs:WP_043012384	DNA topoisomerase I [Corynebacterium jeikeium].	25.31	324	201	9	41	351	265	560	7e-14	84.3
rs:WP_008125031	DNA topoisomerase I [Prevotella timonensis].	26.86	309	193	8	28	334	204	481	7e-14	84.3
rs:WP_018562195	DNA topoisomerase I [Streptomyces sp. BoleA5].	27.21	294	163	12	77	354	302	560	7e-14	84.3
rs:WP_012308892	DNA topoisomerase I [Candidatus Korarchaeum cryptofilum].	25.58	430	254	14	38	447	238	621	7e-14	84.3
rs:WP_046605482	DNA topoisomerase I [Neorhizobium galegae].	24.83	439	267	15	47	452	230	638	7e-14	84.3
rs:WP_046609957	DNA topoisomerase I [Neorhizobium galegae].	24.83	439	267	15	47	452	230	638	7e-14	84.3
rs:WP_008844703	DNA topoisomerase I [Aliiglaciecola lipolytica].	25.38	398	236	13	1	377	206	563	7e-14	84.3
rs:WP_028900957	DNA topoisomerase I [Prevotella timonensis].	26.86	309	193	8	28	334	204	481	7e-14	84.3
rs:WP_027831857	DNA topoisomerase I [Marinobacter sp. HL-58].	24.75	396	238	13	68	446	281	633	7e-14	84.3
rs:WP_019518815	topoisomerase I [Moraxella boevrei].	23.64	423	262	15	36	446	284	657	7e-14	84.3
rs:WP_025478727	DNA topoisomerase, partial [Enterococcus faecium].	29.59	196	132	3	57	249	268	460	7e-14	83.6
rs:WP_031627730	DNA topoisomerase I [Pseudomonas sp. 2_1_26].	24.33	411	246	14	74	459	260	630	7e-14	84.0
rs:WP_045250685	DNA topoisomerase I [Microbacterium azadirachtae].	27.69	325	173	12	51	354	268	551	7e-14	84.3
rs:WP_029588602	DNA topoisomerase I [Campylobacter jejuni].	25.00	424	250	16	47	450	225	600	7e-14	84.3
rs:WP_003882599	MULTISPECIES: DNA topoisomerase I [Mycobacterium].	27.53	356	204	13	77	410	303	626	7e-14	84.3
rs:WP_035002439	DNA topoisomerase I [Corynebacterium jeikeium].	25.31	324	201	9	41	351	265	560	7e-14	84.3
rs:WP_034977859	DNA topoisomerase I [Corynebacterium jeikeium].	25.31	324	201	9	41	351	265	560	7e-14	84.3
rs:WP_006684311	topoisomerase I [Citrobacter youngae].	26.06	376	235	12	77	446	284	622	7e-14	84.3
rs:WP_020366332	DNA topoisomerase III, partial [Staphylococcus epidermidis].	27.27	242	155	6	211	450	4	226	7e-14	82.0
tr:M1NV36_9CORY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.24	469	281	15	30	455	237	669	7e-14	84.3
rs:WP_008238576	DNA topoisomerase I [Pedobacter sp. BAL39].	26.49	302	179	7	36	334	219	480	7e-14	84.3
rs:WP_034971914	DNA topoisomerase I [Corynebacterium jeikeium].	25.31	324	201	9	41	351	265	560	7e-14	84.3
rs:WP_022462183	DNA topoisomerase [Blautia sp. CAG:37].	24.12	427	268	14	48	457	227	614	7e-14	84.0
rs:WP_018043601	DNA topoisomerase I [Methylobacterium sp. 88A].	26.11	429	247	14	57	452	243	634	7e-14	84.3
rs:WP_002730363	DNA topoisomerase I [Phaeospirillum molischianum].	27.03	418	246	15	65	454	249	635	7e-14	84.3
rs:WP_002689561	DNA topoisomerase I [Treponema denticola].	24.48	433	271	15	36	452	232	624	7e-14	84.3
rs:WP_002682495	DNA topoisomerase I [Treponema denticola].	24.48	433	271	15	36	452	232	624	7e-14	84.3
rs:WP_043442525	DNA topoisomerase I [Streptomyces nodosus].	25.96	339	201	11	35	354	250	557	7e-14	84.3
rs:WP_046792747	DNA topoisomerase I [Rhizobium sp. LC145].	25.00	440	265	15	47	452	230	638	7e-14	84.3
tr:R0U479_NEIME	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.13	328	192	10	43	356	228	522	7e-14	84.0
rs:WP_008380089	DNA topoisomerase I [Gordonia malaquae].	25.92	355	214	11	41	377	262	585	7e-14	84.3
rs:WP_040788066	DNA topoisomerase I [Nocardia paucivorans].	25.90	332	198	10	41	356	259	558	7e-14	84.3
rs:WP_027071533	DNA topoisomerase I [Luteimonas sp. J29].	27.57	370	210	14	66	408	254	592	7e-14	84.3
rs:WP_011264301	topoisomerase I [Salmonella enterica].	26.05	380	230	13	77	446	284	622	7e-14	84.3
rs:WP_021812978	DNA topoisomerase I [Psychrobacter aquaticus].	25.32	387	220	16	24	384	245	588	8e-14	84.3
rs:WP_008580070	MULTISPECIES: DNA topoisomerase I [spotted fever group].	24.76	420	239	17	65	449	250	627	8e-14	84.3
rs:WP_040316003	DNA topoisomerase I [Bacteroides stercoris].	25.91	301	183	7	40	334	216	482	8e-14	84.3
rs:XP_011671337	PREDICTED: DNA topoisomerase 3-alpha [Strongylocentrotus purpuratus].	24.08	436	267	14	40	450	279	675	8e-14	84.3
rs:WP_028317283	DNA topoisomerase I [Desulfobulbus elongatus].	24.89	442	256	15	36	458	215	599	8e-14	84.0
rs:WP_033286338	DNA topoisomerase I [Streptomyces sp. NRRL F-525].	27.43	288	170	9	77	354	299	557	8e-14	84.3
rs:WP_015823489	DNA topoisomerase I [Methylobacterium extorquens].	26.61	451	238	19	43	452	236	634	8e-14	84.3
rs:WP_014408458	DNA topoisomerase I [Rickettsia rhipicephali].	25.06	419	239	16	65	449	250	627	8e-14	84.3
rs:WP_044542577	DNA topoisomerase I [Bradyrhizobium sp. LTSP885].	25.28	439	269	13	45	454	228	636	8e-14	84.3
rs:WP_026479789	DNA topoisomerase I [Ahrensia sp. 13_GOM-1096m].	25.76	427	255	13	60	452	241	639	8e-14	84.3
rs:WP_015560448	DNA topoisomerase I [Roseburia intestinalis CAG:13].	23.41	440	281	12	36	457	213	614	8e-14	84.0
rs:WP_034980045	DNA topoisomerase I [Corynebacterium jeikeium].	25.31	324	201	9	41	351	265	560	8e-14	84.3
rs:WP_005138715	DNA topoisomerase I [Mycobacterium rhodesiae].	25.98	381	229	11	41	399	269	618	8e-14	84.3
rs:WP_000513600	topoisomerase I [Escherichia fergusonii].	26.06	376	235	12	77	446	284	622	8e-14	84.3
rs:WP_024759186	DNA topoisomerase I [Streptomyces exfoliatus].	27.30	293	164	11	77	354	299	557	8e-14	84.3
tr:A0A0E9FS87_CHLTH	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CRH85592.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRH85592.1};	26.04	407	220	14	75	452	227	581	8e-14	84.0
rs:WP_027004206	DNA topoisomerase I [Corynebacterium halotolerans].	23.52	472	276	15	30	455	251	683	8e-14	84.3
tr:W6I3A9_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.11	454	270	16	31	452	232	647	8e-14	84.3
rs:WP_014598755	DNA topoisomerase I [Propionibacterium acnes].	25.19	389	237	13	24	388	232	590	8e-14	84.3
rs:WP_046080869	DNA topoisomerase I [Escherichia fergusonii].	26.06	376	235	12	77	446	284	622	8e-14	84.3
rs:WP_037150123	DNA topoisomerase I [Rhizobium sp. YS-1r].	24.60	443	263	17	47	452	230	638	8e-14	84.3
rs:WP_020039083	DNA topoisomerase I [Salipiger mucosus].	26.43	473	245	18	47	454	231	665	8e-14	84.3
tr:A8XHL1_CAEBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.70	367	220	13	39	392	274	604	8e-14	84.3
rs:WP_033251356	DNA topoisomerase I [Kitasatospora phosalacinea].	25.23	329	195	12	42	354	268	561	8e-14	84.3
rs:WP_038640964	DNA topoisomerase I [Citrobacter freundii].	26.06	376	235	12	77	446	284	622	8e-14	84.3
rs:WP_007808660	DNA topoisomerase I [Rhodanobacter spathiphylli].	26.57	335	195	12	69	380	255	561	8e-14	84.3
rs:WP_006857504	DNA topoisomerase I [Roseburia intestinalis].	23.41	440	281	12	36	457	213	614	8e-14	84.0
rs:WP_038805147	DNA topoisomerase I, partial [Salmonella enterica].	26.06	376	235	12	77	446	284	622	8e-14	84.3
rs:WP_032449707	DNA topoisomerase I, partial [Brucella melitensis].	26.32	418	238	15	70	452	253	635	8e-14	84.0
rs:WP_041437548	DNA topoisomerase I, partial [Synechococcus sp. JA-2-3B'a(2-13)].	26.50	351	213	11	41	379	255	572	8e-14	84.3
rs:WP_025724508	DNA topoisomerase I [Acholeplasma granularum].	25.43	350	204	11	110	450	287	588	8e-14	84.0
rs:WP_029719788	DNA topoisomerase I [Saccharopolyspora rectivirgula].	26.43	367	215	13	41	384	277	611	8e-14	84.3
rs:WP_012858472	DNA topoisomerase I [Streptobacillus moniliformis].	23.51	336	207	8	26	350	203	499	8e-14	84.0
rs:WP_023566947	DNA topoisomerase I, partial [Escherichia coli].	26.06	376	235	12	77	446	42	380	8e-14	83.6
tr:A0A067B5R6_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.82	395	233	15	69	446	278	629	8e-14	84.3
rs:WP_044841803	DNA topoisomerase I [Thalassomonas viridans].	25.20	381	231	11	77	446	291	628	8e-14	84.3
rs:WP_022382153	DNA topoisomerase [Dialister sp. CAG:357].	26.51	298	181	9	166	454	375	643	8e-14	84.0
rs:WP_024864222	DNA topoisomerase I [Bartonella doshiae].	27.29	425	234	19	67	452	248	636	8e-14	84.3
rs:WP_010470849	DNA topoisomerase I [Acaryochloris sp. CCMEE 5410].	26.06	376	216	14	27	385	219	549	8e-14	84.0
rs:WP_028641269	DNA topoisomerase I [Novosphingobium acidiphilum].	27.59	406	236	19	69	452	251	620	8e-14	84.3
rs:WP_036397702	DNA topoisomerase I [Mycobacterium cosmeticum].	26.72	378	223	13	55	410	282	627	8e-14	84.3
rs:WP_017445700	hypothetical protein [Gayadomonas joobiniege].	24.27	379	239	11	77	446	289	628	8e-14	84.3
rs:WP_021572102	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	8e-14	84.3
rs:WP_040463505	DNA topoisomerase I [Helicobacter bilis].	22.72	427	268	13	41	450	222	603	8e-14	84.0
rs:WP_027326478	DNA topoisomerase I [Bacteroides pyogenes].	25.86	290	183	7	47	334	223	482	8e-14	84.0
rs:WP_000317025	DNA topoisomerase I subunit omega, partial [Escherichia coli].	26.06	376	235	12	77	446	46	384	8e-14	84.0
rs:WP_015124680	DNA topoisomerase I [Synechococcus sp. PCC 6312].	28.62	311	181	9	77	377	285	564	8e-14	84.3
rs:WP_002693373	DNA topoisomerase I [Treponema denticola].	24.48	433	271	15	36	452	232	624	8e-14	84.0
rs:WP_028919946	DNA topoisomerase I [Pseudoxanthomonas suwonensis].	29.57	301	166	11	66	350	254	524	8e-14	84.3
rs:WP_010229101	DNA topoisomerase I [Chlamydia muridarum].	23.88	448	262	18	28	449	228	622	8e-14	84.3
rs:WP_002818660	DNA topoisomerase I [Campylobacter coli].	25.35	426	246	17	47	450	225	600	8e-14	84.0
rs:WP_009463185	DNA topoisomerase I [Ahrensia sp. R2A130].	25.06	439	251	16	47	452	240	633	8e-14	84.3
rs:WP_002405920	DNA topoisomerase, partial [Enterococcus faecalis].	30.41	217	136	5	52	264	264	469	8e-14	83.6
rs:WP_040726675	DNA topoisomerase I [Thiomicrospira sp. Kp2].	27.05	292	174	7	47	335	223	478	8e-14	84.3
tr:N2BCF8_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.95	427	267	14	41	450	277	658	8e-14	84.0
rs:WP_020100958	DNA topoisomerase I [Mycobacterium sp. 360MFTsu5.1].	26.58	316	184	11	55	354	281	564	8e-14	84.3
rs:WP_029118984	DNA topoisomerase I [Mycobacterium sp. UNC410CL29Cvi84].	26.58	316	184	11	55	354	281	564	8e-14	84.3
rs:WP_015951693	DNA topoisomerase I [Methylobacterium extorquens].	26.06	449	243	17	43	452	236	634	8e-14	84.3
rs:WP_003448703	topoisomerase I - like protein, partial [Pseudomonas aeruginosa].	24.39	410	247	13	74	459	72	442	8e-14	83.6
rs:WP_037215870	DNA topoisomerase I [Rhizobium sp. IBUN].	25.28	439	265	15	47	452	230	638	8e-14	84.3
rs:WP_022191330	DNA topoisomerase [Firmicutes bacterium CAG:240].	26.76	426	257	13	47	454	228	616	8e-14	84.0
rs:WP_028914417	DNA topoisomerase I [Pseudoxanthomonas sp. J31].	29.24	301	167	11	66	350	254	524	8e-14	84.0
rs:WP_012881931	DNA topoisomerase I [Dehalococcoides mccartyi].	21.83	449	256	12	65	450	245	661	8e-14	84.0
tr:A9MQ04_SALAR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.06	376	235	12	77	446	284	622	8e-14	84.3
rs:XP_001785482	predicted protein [Physcomitrella patens].	25.56	446	270	15	37	452	261	674	8e-14	84.3
tr:B0N9B4_CLOSV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.67	414	263	10	60	457	253	629	8e-14	84.0
rs:WP_036290936	DNA topoisomerase I [Methylosinus sp. PW1].	25.23	428	249	14	60	452	243	634	8e-14	84.3
rs:WP_019399203	DNA topoisomerase I [Pseudoxanthomonas sp. GW2].	29.24	301	167	11	66	350	254	524	8e-14	84.0
tr:W4PGQ1_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.86	290	183	7	47	334	287	546	8e-14	84.0
rs:WP_000520438	topoisomerase I [Vibrio sp. RC341].	25.82	395	233	15	69	446	278	629	8e-14	84.3
rs:WP_033180310	DNA topoisomerase I [Rhizobium leguminosarum].	24.66	438	269	14	47	452	230	638	8e-14	84.3
rs:WP_002872293	DNA topoisomerase I [Campylobacter jejuni].	25.58	434	250	18	47	458	225	607	8e-14	84.0
rs:WP_034352732	DNA topoisomerase I [Deinococcus phoenicis].	26.14	329	188	11	37	344	247	541	8e-14	84.3
rs:WP_027671233	DNA topoisomerase I [Rheinheimera baltica].	27.19	320	193	9	42	356	244	528	8e-14	84.0
rs:WP_044832579	DNA topoisomerase I [Thalassomonas actiniarum].	25.93	378	232	13	77	446	291	628	8e-14	84.3
rs:WP_040422144	DNA topoisomerase I [Corynebacterium lipophiloflavum].	27.00	300	167	10	66	351	278	539	8e-14	84.3
rs:WP_001583462	DNA topoisomerase 1 [Escherichia coli].	26.06	376	235	12	77	446	284	622	8e-14	84.0
rs:WP_018857025	DNA topoisomerase I [Rhizobium sp. 42MFCr.1].	25.28	439	265	15	47	452	230	638	8e-14	84.3
tr:Q2JJ84_SYNJB	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.50	351	213	11	41	379	255	572	8e-14	84.3
rs:WP_006996046	topoisomerase I [Haemophilus aegyptius].	25.59	379	233	14	77	446	290	628	8e-14	84.0
rs:WP_012613184	DNA topoisomerase I [Desulfovibrio vulgaris].	25.18	417	257	14	53	452	231	609	8e-14	84.0
rs:WP_032449677	DNA topoisomerase I [Brucella melitensis].	26.32	418	238	15	70	452	253	635	8e-14	84.0
rs:WP_033202856	DNA topoisomerase I [Streptomyces wedmorensis].	27.30	293	164	11	77	354	299	557	8e-14	84.3
rs:WP_028928297	DNA topoisomerase I [Pseudoxanthomonas suwonensis].	29.57	301	166	11	66	350	254	524	8e-14	84.0
tr:C0XU91_9CORY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.00	300	167	10	66	351	287	548	8e-14	84.3
rs:WP_024515569	DNA topoisomerase I [Bradyrhizobium sp. Tv2a-2].	24.59	427	257	13	60	454	243	636	8e-14	84.3
rs:WP_039403381	DNA topoisomerase I, partial [Microbacterium mangrovi].	28.62	318	178	11	48	354	270	549	9e-14	84.0
rs:WP_012844201	DNA topoisomerase I [Rhodothermus marinus].	26.65	349	215	11	41	377	254	573	9e-14	84.0
tr:A0A016QU65_9DEIO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.14	329	188	11	37	344	242	536	9e-14	84.3
tr:Q01N68_SOLUE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.10	341	202	10	36	356	216	526	9e-14	84.3
rs:WP_042963560	DNA topoisomerase I [Campylobacter coli].	24.77	432	253	17	41	450	219	600	9e-14	84.0
rs:WP_002825508	DNA topoisomerase I [Campylobacter coli].	24.77	432	253	17	41	450	219	600	9e-14	84.0
rs:WP_024455846	MULTISPECIES: DNA topoisomerase I [Mycobacterium].	26.72	378	223	13	55	410	282	627	9e-14	84.3
rs:WP_043614100	DNA topoisomerase I [Ensifer sp. ZNC0028].	25.11	442	262	15	47	452	230	638	9e-14	84.0
rs:WP_009262778	DNA topoisomerase I [Lachnospiraceae bacterium 9_1_43BFAA].	23.53	425	273	12	48	457	227	614	9e-14	84.0
rs:WP_029206007	DNA topoisomerase I [alpha proteobacterium SCGC AAA487-M09].	25.11	442	262	14	49	454	232	640	9e-14	84.0
tr:C6L9V4_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.83	428	268	12	48	457	235	622	9e-14	84.0
rs:XP_002011041	GI16324 [Drosophila mojavensis].	25.14	354	222	13	37	382	255	573	9e-14	84.0
rs:WP_024473153	DNA topoisomerase I [Morganella morganii].	25.77	388	238	14	77	452	281	630	9e-14	84.0
rs:WP_004239222	MULTISPECIES: DNA topoisomerase I [Morganella].	25.77	388	238	14	77	452	281	630	9e-14	84.0
rs:WP_033386012	topoisomerase I, partial [Lactobacillus suebicus].	31.07	177	112	4	223	397	1	169	9e-14	81.3
rs:WP_045052677	DNA topoisomerase I [Chroococcales cyanobacterium CENA595].	26.11	337	211	8	41	370	249	554	9e-14	84.0
tr:A3IRZ5_9CHRO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.06	427	234	16	40	436	261	631	9e-14	84.0
rs:WP_037345451	DNA topoisomerase I [Sciscionella sp. SE31].	26.43	401	236	14	30	409	259	621	9e-14	84.0
rs:WP_043371813	DNA topoisomerase I [Streptomyces mutabilis].	26.11	337	203	10	35	354	250	557	9e-14	84.0
rs:WP_025392403	DNA topoisomerase I [Desulfurella acetivorans].	23.09	433	239	13	77	454	256	649	9e-14	84.0
rs:WP_046707521	DNA topoisomerase I [Streptomyces europaeiscabiei].	25.38	390	235	13	42	409	264	619	9e-14	84.0
rs:WP_032449797	DNA topoisomerase I [Brucella melitensis].	26.32	418	238	15	70	452	253	635	9e-14	84.0
rs:XP_652633	DNA topoisomerase III [Entamoeba histolytica HM-1:IMSS].	24.16	389	246	12	30	399	241	599	9e-14	84.0
rs:WP_017969400	DNA topoisomerase I [alpha proteobacterium SCGC AAA280-P20].	24.72	441	263	14	50	454	233	640	9e-14	84.0
rs:WP_012391203	DNA topoisomerase I [Lactobacillus fermentum].	25.12	414	231	20	65	452	267	627	9e-14	84.0
rs:WP_015954503	DNA topoisomerase I [Cyanothece sp. PCC 7424].	24.51	457	259	18	29	450	224	629	9e-14	84.0
rs:WP_009246427	DNA topoisomerase I [Lachnospiraceae bacterium 6_1_63FAA].	24.71	429	263	13	48	457	227	614	9e-14	84.0
rs:WP_028509937	DNA topoisomerase I [Ruminococcus sp. NK3A76].	22.86	433	273	14	41	452	219	611	9e-14	84.0
rs:WP_028487358	DNA topoisomerase I [Thiomicrospira chilensis].	26.44	348	204	10	23	360	205	510	9e-14	84.0
rs:WP_028452852	DNA topoisomerase I [Chitinilyticum aquatile].	26.22	431	255	16	43	452	228	616	9e-14	84.0
rs:WP_016153252	MULTISPECIES: DNA topoisomerase 1 [Enterobacteriaceae].	26.06	376	235	12	77	446	284	622	9e-14	84.0
rs:WP_026160957	DNA topoisomerase I [Sinorhizobium medicae].	23.86	440	270	14	47	452	230	638	9e-14	84.0
rs:WP_024311648	MULTISPECIES: DNA topoisomerase I [Sinorhizobium].	23.86	440	270	14	47	452	230	638	9e-14	84.0
rs:WP_032206808	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	9e-14	84.0
rs:WP_044444103	DNA topoisomerase I [Bacillus mycoides].	31.82	176	112	5	281	454	408	577	9e-14	84.0
rs:WP_044444103	DNA topoisomerase I [Bacillus mycoides].	27.65	170	117	3	35	201	239	405	4e-09	69.3
tr:C7H1C5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.05	246	166	6	47	286	235	475	9e-14	83.6
rs:WP_011990971	DNA topoisomerase I [Campylobacter jejuni].	25.35	426	246	17	47	450	225	600	9e-14	84.0
tr:T0TU76_LACFE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.12	414	231	20	65	452	267	627	9e-14	84.0
rs:WP_038551051	DNA topoisomerase I [Corynebacterium glyciniphilum].	26.50	351	209	13	77	409	310	629	9e-14	84.0
rs:WP_011722224	MULTISPECIES: DNA topoisomerase I [Clostridium].	24.19	434	258	17	47	457	226	611	9e-14	84.0
rs:WP_039673374	DNA topoisomerase I [Corynebacterium minutissimum].	24.93	365	217	12	41	384	253	581	9e-14	84.0
rs:WP_025435532	DNA topoisomerase I [Eubacterium acidaminophilum].	22.01	427	270	11	48	456	226	607	9e-14	84.0
rs:WP_017933258	DNA topoisomerase I [Nocardioides sp. Iso805N].	28.17	355	201	13	42	377	255	574	9e-14	84.0
rs:WP_032359226	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	9e-14	84.0
rs:WP_043016148	DNA topoisomerase I [Citrobacter freundii].	26.06	376	235	12	77	446	284	622	9e-14	84.0
rs:WP_039909173	DNA topoisomerase I [[Clostridium] scindens].	23.67	414	263	10	60	457	239	615	9e-14	84.0
rs:WP_006101735	DNA topoisomerase I [Coleofasciculus chthonoplastes].	25.70	393	236	12	26	405	225	574	9e-14	84.0
rs:WP_039190177	DNA topoisomerase I [Aureimonas altamirensis].	25.49	455	266	18	38	449	215	639	9e-14	84.0
tr:H8ZDZ0_NEMS1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.82	364	229	13	39	397	249	576	9e-14	84.0
rs:WP_010431771	topoisomerase I [Enterobacter mori].	26.05	380	230	14	77	446	284	622	9e-14	84.0
rs:WP_037117487	MULTISPECIES: DNA topoisomerase I [Rhizobium].	24.83	439	267	14	47	452	230	638	9e-14	84.0
rs:WP_036294629	hypothetical protein, partial [Methylobacter whittenburyi].	27.46	346	195	13	61	393	237	539	9e-14	83.6
tr:A0A087AVV4_9BIFI	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:KFI62904.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KFI62904.1};	28.21	397	233	19	79	445	266	640	9e-14	84.0
rs:WP_013114828	DNA topoisomerase I [Brachyspira murdochii].	22.03	454	261	17	50	449	251	665	9e-14	84.0
rs:WP_016230148	DNA topoisomerase I [Lachnospiraceae bacterium 10-1].	23.36	428	263	13	48	454	227	610	9e-14	84.0
gp:CP001852_576	DNA topoisomerase I [Brucella melitensis M5-90]	26.32	418	238	15	70	452	262	644	9e-14	84.0
rs:WP_035240901	DNA topoisomerase I [Desulfobacter vibrioformis].	24.59	431	254	16	47	452	225	609	9e-14	84.0
rs:WP_016918982	DNA topoisomerase I [Methylocystis parvus].	26.57	429	242	17	60	452	243	634	9e-14	84.0
rs:WP_030838062	DNA topoisomerase I [Streptomyces hygroscopicus].	25.30	328	196	11	42	354	270	563	1e-13	84.0
rs:WP_002869288	DNA topoisomerase I [Campylobacter jejuni].	25.35	426	246	17	47	450	225	600	1e-13	84.0
rs:WP_002826940	DNA topoisomerase I [Campylobacter coli].	25.35	426	246	17	47	450	225	600	1e-13	84.0
rs:WP_046025708	DNA topoisomerase I [Lactobacillus fermentum].	25.12	414	231	20	65	452	267	627	1e-13	84.0
rs:XP_012749000	hypothetical protein SAMD00019534_112170 [Acytostelium subglobosum LB1].	24.86	346	219	9	39	378	259	569	1e-13	84.0
rs:WP_040832976	DNA topoisomerase I [Nocardia brevicatena].	26.46	325	183	11	47	356	293	576	1e-13	84.0
rs:XP_003704123	PREDICTED: DNA topoisomerase 3-beta-1 [Megachile rotundata].	24.17	360	225	13	37	385	258	580	1e-13	84.0
rs:XP_007048480	Topoisomerase 3alpha isoform 1 [Theobroma cacao].	24.15	439	273	14	39	451	264	668	1e-13	84.0
tr:I8YT13_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.99	326	194	12	40	354	248	540	1e-13	84.0
rs:WP_044471025	DNA topoisomerase I [Mannheimia sp. MG13].	24.94	409	248	15	47	446	270	628	1e-13	84.0
tr:J7BXN5_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.02	187	123	3	54	237	12	195	1e-13	80.1
rs:WP_035428782	DNA topoisomerase I [Lactobacillus fermentum].	25.12	414	231	20	65	452	267	627	1e-13	84.0
rs:WP_012397547	DNA topoisomerase I [Kocuria rhizophila].	27.62	344	184	14	42	354	267	576	1e-13	84.0
rs:WP_013133690	DNA topoisomerase I [Thermobispora bispora].	26.27	316	189	11	77	377	297	583	1e-13	84.0
rs:WP_035572607	DNA topoisomerase I [Hyphomonas adhaerens].	24.66	438	271	13	41	452	225	629	1e-13	84.0
rs:WP_032449714	DNA topoisomerase I [Brucella melitensis].	26.32	418	238	15	70	452	253	635	1e-13	84.0
rs:WP_024869872	DNA topoisomerase I [Pseudoxanthomonas suwonensis].	29.57	301	166	11	66	350	254	524	1e-13	84.0
rs:WP_036443188	DNA topoisomerase I [Mycoplasma hyosynoviae].	23.48	379	217	13	92	449	271	597	1e-13	83.6
tr:W8FAX8_RHIRD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.99	454	262	17	38	452	179	597	1e-13	84.0
tr:T0ZDY5_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EQD42442.1};	29.11	347	184	15	66	387	254	563	1e-13	84.0
rs:WP_038814824	DNA topoisomerase I [Campylobacter jejuni].	24.88	430	243	18	47	450	225	600	1e-13	83.6
rs:WP_002932097	DNA topoisomerase I [Campylobacter jejuni].	25.35	426	246	17	47	450	225	600	1e-13	83.6
gpu:CP008775_519	DNA topoisomerase I [Brucella abortus]	26.32	418	238	15	70	452	262	644	1e-13	84.0
rs:WP_021935813	DNA topoisomerase [Bacteroides salyersiae].	26.99	326	194	12	40	354	216	508	1e-13	84.0
rs:WP_002574864	MULTISPECIES: DNA topoisomerase I [Lachnoclostridium].	23.00	426	273	12	48	457	233	619	1e-13	83.6
rs:WP_002966029	MULTISPECIES: DNA topoisomerase I [Brucella].	26.32	418	238	15	70	452	253	635	1e-13	84.0
rs:WP_009364289	DNA topoisomerase I [Brucella sp. BO2].	26.68	416	239	15	70	452	253	635	1e-13	84.0
rs:WP_007531862	DNA topoisomerase I [Rhizobium mesoamericanum].	25.28	439	265	15	47	452	230	638	1e-13	84.0
rs:WP_035393414	DNA topoisomerase III, partial [Faecalibacterium prausnitzii].	28.05	246	166	6	47	286	235	475	1e-13	83.2
rs:WP_017972098	DNA topoisomerase I [alpha proteobacterium SCGC AAA280-B11].	24.49	441	268	13	48	454	231	640	1e-13	84.0
tr:D7H751_BRUAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.32	418	238	15	70	452	262	644	1e-13	84.0
tr:T0E7I0_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.65	284	187	9	77	357	2	261	1e-13	80.9
rs:WP_002968433	MULTISPECIES: DNA topoisomerase I [Brucella].	26.32	418	238	15	70	452	253	635	1e-13	84.0
rs:WP_040022574	DNA topoisomerase I [Streptomyces sp. 150FB].	25.60	336	202	11	37	354	252	557	1e-13	84.0
rs:WP_002780003	DNA topoisomerase I [Campylobacter coli].	25.35	426	246	17	47	450	225	600	1e-13	83.6
rs:WP_046252353	DNA topoisomerase I [Mycobacterium chelonae].	26.65	379	229	11	41	399	252	601	1e-13	84.0
rs:WP_030095868	DNA topoisomerase I [Mycobacterium abscessus].	26.65	379	229	11	41	399	252	601	1e-13	84.0
rs:WP_004687268	DNA topoisomerase I [Brucella neotomae].	26.68	416	239	15	70	452	253	635	1e-13	84.0
rs:WP_041859254	hypothetical protein, partial [Candidatus Solibacter usitatus].	26.10	341	202	10	36	356	216	526	1e-13	84.0
rs:XP_002107874	hypothetical protein TRIADDRAFT_49643 [Trichoplax adhaerens].	24.26	437	259	15	40	453	259	646	1e-13	84.0
rs:WP_014562385	DNA topoisomerase I [Lactobacillus fermentum].	25.12	414	231	20	65	452	267	627	1e-13	83.6
rs:WP_046519309	DNA topoisomerase I [Rheinheimera sp. IITR-13].	25.59	465	287	15	1	446	195	619	1e-13	84.0
tr:D4L803_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.03	466	263	17	40	449	218	648	1e-13	83.6
rs:WP_030440735	DNA topoisomerase I [Actinoplanes subtropicus].	27.60	366	209	16	42	386	261	591	1e-13	84.0
rs:WP_032449829	DNA topoisomerase I [Brucella abortus].	26.32	418	238	15	70	452	253	635	1e-13	84.0
rs:WP_037225084	DNA topoisomerase I [Roseomonas gilardii].	25.12	426	259	14	60	454	244	640	1e-13	84.0
rs:WP_040849999	DNA topoisomerase I [Thiovulum sp. ES].	25.32	395	232	14	73	450	253	601	1e-13	83.6
rs:WP_032450952	DNA topoisomerase I [Brucella sp. 63/311].	26.71	423	230	16	70	452	253	635	1e-13	84.0
rs:WP_037968522	DNA topoisomerase I [Streptomyces sp. SS].	27.30	293	164	11	77	354	299	557	1e-13	84.0
rs:WP_015409059	DNA topoisomerase I [Natronomonas moolapensis].	23.33	403	262	13	61	454	266	630	1e-13	84.0
rs:WP_028316527	DNA topoisomerase I [Desulfatibacillum aliphaticivorans].	23.97	484	291	19	1	452	170	608	1e-13	83.6
rs:WP_002856309	MULTISPECIES: DNA topoisomerase I [Campylobacter].	25.35	426	246	17	47	450	225	600	1e-13	83.6
tr:F0L2J3_AGRSH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.99	454	262	17	38	452	231	649	1e-13	84.0
tr:R8VV53_9CLOT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.81	430	258	15	50	454	227	620	1e-13	84.0
rs:WP_033760176	DNA topoisomerase I [Helicobacter pylori].	24.71	429	257	17	41	450	218	599	1e-13	83.6
rs:WP_002922085	DNA topoisomerase I [Campylobacter jejuni].	24.77	432	253	17	41	450	219	600	1e-13	83.6
rs:WP_002911147	DNA topoisomerase I [Campylobacter jejuni].	25.35	426	246	17	47	450	225	600	1e-13	83.6
rs:WP_003141417	DNA topoisomerase I [Pseudomonas aeruginosa].	24.69	405	254	13	74	459	260	632	1e-13	83.6
tr:A0A0F4H4Z2_MORMO	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:KJY04569.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KJY04569.1};	25.77	388	238	14	77	452	213	562	1e-13	84.0
rs:WP_044163613	DNA topoisomerase I [Bacteroides reticulotermitis].	27.46	295	172	8	47	334	223	482	1e-13	83.6
rs:WP_000520436	MULTISPECIES: topoisomerase I [Vibrio].	26.43	401	223	16	69	446	278	629	1e-13	84.0
rs:XP_004518397	PREDICTED: DNA topoisomerase 3-beta [Ceratitis capitata].	24.44	356	228	12	37	385	256	577	1e-13	84.0
rs:WP_035427363	DNA topoisomerase I [Lactobacillus fermentum].	25.12	414	231	20	65	452	265	625	1e-13	83.6
rs:WP_042910570	DNA topoisomerase I [Mycobacterium intracellulare].	25.00	380	233	11	41	399	271	619	1e-13	84.0
rs:WP_041694374	DNA topoisomerase I [Agrobacterium sp. H13-3].	25.99	454	262	17	38	452	220	638	1e-13	84.0
rs:WP_005154109	topoisomerase I [Shigella sonnei].	25.80	376	236	12	77	446	284	622	1e-13	84.0
tr:Q8YC66_BRUME	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.32	418	238	15	70	452	277	659	1e-13	84.0
rs:WP_004141651	DNA topoisomerase I [Cardiobacterium hominis].	28.18	330	197	9	60	380	247	545	1e-13	83.6
rs:WP_011013552	DNA topoisomerase I [Corynebacterium glutamicum].	24.71	340	209	9	31	354	256	564	1e-13	84.0
rs:WP_040708059	DNA topoisomerase I, partial [Oceanibaculum indicum].	25.65	421	248	16	65	454	251	637	1e-13	84.0
tr:X5DQT1_9CORY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000313|EMBL:AHW63022.1}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000313|EMBL:AHW63022.1}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.50	351	209	13	77	409	330	649	1e-13	84.0
rs:WP_040332936	DNA topoisomerase I, partial [Butyricicoccus pullicaecorum].	25.81	430	258	15	50	454	227	620	1e-13	83.6
tr:J0V077_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.32	395	232	14	73	450	260	608	1e-13	83.6
rs:WP_014660517	DNA topoisomerase I [Helicobacter cetorum].	24.54	432	254	17	41	450	218	599	1e-13	83.6
rs:WP_032280486	DNA topoisomerase 1 [Escherichia coli].	25.80	376	236	12	77	446	284	622	1e-13	84.0
tr:J1JDU2_BARDO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.29	425	234	19	67	452	264	652	1e-13	84.0
rs:WP_035423519	DNA topoisomerase I [Lactobacillus fermentum].	25.12	414	231	20	65	452	267	627	1e-13	83.6
rs:WP_023466136	DNA topoisomerase I [Lactobacillus fermentum].	25.12	414	231	20	65	452	267	627	1e-13	83.6
rs:WP_032450281	DNA topoisomerase I [Brucella sp. NVSL 07-0026].	26.68	416	239	15	70	452	253	635	1e-13	84.0
rs:WP_033518198	DNA topoisomerase III, partial [Bifidobacterium cuniculi].	28.21	397	233	19	79	445	266	640	1e-13	83.6
rs:WP_005758915	topoisomerase I [Pasteurella bettyae].	25.40	378	235	13	77	446	290	628	1e-13	84.0
tr:K9D1Y5_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.06	427	260	13	50	457	197	582	1e-13	83.6
rs:WP_041319014	DNA topoisomerase I [Mycobacterium sinense].	27.79	331	188	12	66	377	289	587	1e-13	84.0
rs:WP_025593271	DNA topoisomerase I [Agrobacterium tumefaciens].	25.99	454	262	17	38	452	220	638	1e-13	84.0
rs:WP_029343511	DNA topoisomerase I [Lactococcus garvieae].	23.11	437	273	13	34	452	239	630	1e-13	83.6
rs:WP_027764162	DNA topoisomerase I [Streptomyces sp. CNS606].	26.96	293	165	11	77	354	306	564	1e-13	84.0
tr:D0DRB1_LACFE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.12	414	231	20	65	452	265	625	1e-13	83.6
rs:WP_039865010	DNA topoisomerase I [Holdemania filiformis].	23.13	467	259	14	47	451	225	653	1e-13	83.6
tr:K2JZ46_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.65	421	248	16	65	454	251	637	1e-13	84.0
rs:WP_042619786	DNA topoisomerase I [Agrobacterium tumefaciens].	24.94	441	264	14	47	452	231	639	1e-13	84.0
rs:WP_008800967	DNA topoisomerase III [Fusobacterium gonidiaformans].	23.02	404	263	12	60	439	264	643	1e-13	83.6
rs:WP_041027941	DNA topoisomerase I, partial [Salmonella enterica].	27.73	321	186	12	77	386	284	569	1e-13	83.6
rs:WP_031612378	DNA topoisomerase III, partial [Salmonella enterica].	44.32	88	49	0	36	123	242	329	1e-13	81.6
rs:WP_036190436	DNA topoisomerase I [Marinobacterium sp. AK27].	25.66	378	232	14	77	446	295	631	1e-13	84.0
rs:WP_008716355	DNA topoisomerase I [Clostridiales bacterium 1_7_47FAA].	24.35	423	265	13	48	454	233	616	1e-13	83.6
rs:WP_032549444	DNA topoisomerase I [Vibrio fortis].	24.73	376	239	12	77	446	290	627	1e-13	84.0
rs:WP_001394200	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	1e-13	83.6
rs:WP_023376403	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	27.73	321	186	12	77	386	284	569	1e-13	83.6
rs:WP_047639253	DNA topoisomerase I [Rhizobium tropici].	25.00	440	266	14	47	452	230	639	1e-13	84.0
rs:XP_012256009	PREDICTED: DNA topoisomerase 3-alpha [Athalia rosae].	25.30	419	242	13	60	449	317	693	1e-13	84.0
rs:WP_001761127	DNA topoisomerase 1 [Escherichia coli].	25.80	376	236	12	77	446	284	622	1e-13	83.6
rs:WP_040781672	DNA topoisomerase I, partial [Marvinbryantia formatexigens].	23.83	428	268	12	48	457	227	614	1e-13	83.6
rs:WP_035623890	DNA topoisomerase I, partial [Lachnospiraceae bacterium C6A11].	24.60	435	266	13	43	457	216	608	1e-13	83.6
rs:WP_002822893	DNA topoisomerase I [Campylobacter coli].	25.35	426	246	17	47	450	225	600	1e-13	83.6
rs:WP_034795369	DNA topoisomerase I [Ensifer adhaerens].	24.72	441	265	14	47	452	230	638	1e-13	83.6
rs:WP_014614088	DNA topoisomerase I [Staphylococcus pseudintermedius].	22.46	423	267	15	49	452	226	606	1e-13	83.6
rs:WP_021033792	DNA topoisomerase I [Campylobacter coli].	25.23	432	251	17	41	450	219	600	1e-13	83.6
rs:WP_048304372	DNA topoisomerase I [Pseudomonas aeruginosa].	26.48	287	175	7	166	446	345	601	1e-13	83.6
rs:WP_037194447	DNA topoisomerase I [Rhizobium sp. OK494].	25.00	440	266	14	47	452	230	639	1e-13	83.6
rs:WP_044710918	DNA topoisomerase I, partial [Citrobacter freundii].	26.58	380	228	14	77	446	284	622	1e-13	83.6
rs:WP_036353378	DNA topoisomerase I [Microvirga sp. BSC39].	24.45	454	262	15	34	452	227	634	1e-13	83.6
rs:WP_038582249	DNA topoisomerase I [Corynebacterium glutamicum].	24.71	340	209	9	31	354	256	564	1e-13	84.0
rs:WP_022005878	DNA topoisomerase [Proteobacteria bacterium CAG:495].	28.67	436	247	18	47	454	228	627	1e-13	83.6
rs:WP_019443384	DNA topoisomerase I [Brucella abortus].	26.68	416	239	15	70	452	253	635	1e-13	83.6
rs:WP_002538592	DNA topoisomerase I [Propionibacterium acnes].	25.26	384	227	14	35	388	237	590	1e-13	83.6
rs:WP_022232935	DNA topoisomerase [Bacteroides sp. CAG:443].	26.90	290	157	8	77	345	249	504	1e-13	83.6
rs:WP_018052407	hypothetical protein [Marinimicrobia bacterium SCGC AB-629-J13].	25.42	354	215	11	47	386	249	567	1e-13	83.6
rs:WP_008598832	MULTISPECIES: DNA topoisomerase I [Propionibacterium].	25.26	384	227	14	35	388	237	590	1e-13	83.6
rs:WP_028587743	DNA topoisomerase I [Desulfocurvus vexinensis].	23.89	427	268	12	43	452	220	606	1e-13	83.6
rs:WP_006641508	MULTISPECIES: DNA topoisomerase I [Brucella].	26.68	416	239	15	70	452	253	635	1e-13	83.6
rs:XP_012287249	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Orussus abietinus].	24.26	441	268	14	39	452	295	696	1e-13	84.0
rs:WP_023169833	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	27.73	321	186	12	77	386	284	569	1e-13	83.2
tr:F5YSD3_MYCSD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.79	331	188	12	66	377	279	577	1e-13	83.6
rs:WP_033744865	DNA topoisomerase I [Helicobacter pylori].	24.01	429	260	16	41	450	218	599	1e-13	83.6
rs:WP_022343868	DNA topoisomerase [Clostridium sp. CAG:356].	22.78	417	277	10	47	452	226	608	1e-13	83.6
tr:A0A0A1MTC0_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.86	468	284	17	18	453	194	616	1e-13	83.6
rs:WP_027404227	DNA topoisomerase I [Aphanizomenon flos-aquae].	25.23	440	262	17	28	443	225	621	1e-13	83.6
rs:WP_025487140	DNA topoisomerase I [Clostridiales bacterium VE202-28].	24.35	423	265	13	48	454	233	616	1e-13	83.6
rs:WP_039433148	DNA topoisomerase I [Vibrio navarrensis].	25.14	358	221	10	40	386	253	574	1e-13	83.6
tr:C3XFJ0_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.95	427	267	14	41	450	277	658	1e-13	83.6
rs:WP_002522977	MULTISPECIES: DNA topoisomerase I [Propionibacterium].	25.26	384	227	14	35	388	237	590	1e-13	83.6
rs:WP_047713457	DNA topoisomerase I [Pantoea ananatis].	25.32	387	241	12	77	452	284	633	1e-13	83.6
rs:WP_019508442	DNA topoisomerase I [Pleurocapsa sp. PCC 7319].	24.26	371	233	11	41	396	249	586	1e-13	83.6
tr:A0A0A8W8B0_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.60	313	207	11	49	357	252	539	1e-13	83.6
rs:WP_009372033	DNA topoisomerase I [Veillonella sp. oral taxon 158].	23.47	426	265	13	47	454	251	633	1e-13	83.6
rs:WP_003512719	MULTISPECIES: DNA topoisomerase I [Agrobacterium].	25.99	454	262	17	38	452	220	638	1e-13	83.6
rs:WP_007572797	DNA topoisomerase I [Prevotella multisaccharivorax].	27.24	312	191	10	30	338	203	481	1e-13	83.6
rs:WP_036351320	DNA topoisomerase I [Microvirga lupini].	24.78	456	258	18	34	452	227	634	1e-13	83.6
rs:WP_021132544	DNA topoisomerase I subunit omega [Phaeospirillum fulvum].	26.79	418	247	14	65	454	249	635	1e-13	83.6
rs:WP_035863952	DNA topoisomerase I [Kitasatospora cheerisanensis].	25.23	329	195	12	42	354	265	558	1e-13	83.6
rs:WP_026100121	DNA topoisomerase I [Microchaete sp. PCC 7126].	26.20	313	190	9	77	379	291	572	1e-13	83.6
rs:WP_022162924	DNA topoisomerase [Bacteroides sp. CAG:633].	28.03	264	150	7	77	334	253	482	1e-13	83.6
rs:WP_039066768	DNA topoisomerase I [Staphylococcus xylosus].	24.30	395	237	14	77	452	254	605	1e-13	83.6
rs:WP_002530121	DNA topoisomerase I [Propionibacterium acnes].	25.26	384	227	14	35	388	237	590	1e-13	83.6
rs:WP_002524667	DNA topoisomerase I [Propionibacterium acnes].	25.26	384	227	14	35	388	237	590	1e-13	83.6
rs:WP_003020611	MULTISPECIES: topoisomerase I [Citrobacter].	26.06	376	235	12	77	446	284	622	1e-13	83.6
rs:WP_012635699	DNA topoisomerase I [Halothermothrix orenii].	23.82	445	248	14	60	450	240	647	1e-13	83.6
rs:WP_003120981	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	24.39	410	247	13	74	459	260	630	1e-13	83.2
rs:WP_036109494	MULTISPECIES: DNA topoisomerase I [Luteibacter].	26.42	386	227	14	44	405	232	584	1e-13	83.6
tr:E9YZQ1_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.15	371	231	12	77	440	298	632	1e-13	83.6
rs:WP_013533917	DNA topoisomerase I [Pseudoxanthomonas suwonensis].	30.56	301	163	12	66	350	254	524	1e-13	83.6
rs:WP_041888640	DNA topoisomerase I, partial [Candidatus Aerophobus profundus].	27.11	402	220	19	77	454	253	605	1e-13	83.6
rs:XP_007333751	hypothetical protein AGABI1DRAFT_46203 [Agaricus bisporus var. burnettii JB137-S8].	25.65	382	233	11	39	405	256	601	1e-13	83.6
rs:WP_005137003	topoisomerase I [Shigella sonnei].	25.80	376	236	12	77	446	284	622	1e-13	83.6
rs:WP_036850036	DNA topoisomerase I [Porphyromonas macacae].	26.77	325	185	11	40	352	221	504	1e-13	83.6
rs:WP_023487490	DNA topoisomerase I [Propionibacterium acnes].	25.26	384	227	14	35	388	237	590	1e-13	83.6
rs:WP_002519968	MULTISPECIES: DNA topoisomerase I [Propionibacterium].	25.26	384	227	14	35	388	237	590	1e-13	83.6
rs:WP_039025800	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	1e-13	83.6
rs:WP_044175108	DNA topoisomerase I [Enterobacter massiliensis].	26.68	386	220	16	77	446	284	622	1e-13	83.6
rs:WP_007789732	DNA topoisomerase I [Rhizobium sp. CF122].	25.28	439	265	15	47	452	230	638	1e-13	83.6
rs:WP_006641755	MULTISPECIES: DNA topoisomerase I [Brucella].	26.68	416	239	15	70	452	253	635	1e-13	83.6
gp:CP003166_1148	DNA topoisomerase I [Staphylococcus aureus subsp. aureus M013]	26.49	302	171	15	166	452	66	331	1e-13	82.4
rs:WP_034056250	DNA topoisomerase I [Pseudomonas aeruginosa].	26.48	287	175	7	166	446	355	611	1e-13	83.6
rs:XP_012287248	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Orussus abietinus].	24.26	441	268	14	39	452	295	696	1e-13	83.6
rs:WP_010412954	DNA topoisomerase I [Citromicrobium sp. JLT1363].	28.21	397	232	13	22	400	194	555	1e-13	83.6
rs:WP_002517381	DNA topoisomerase I [Propionibacterium acnes].	25.26	384	227	14	35	388	237	590	1e-13	83.6
rs:WP_014172429	DNA topoisomerase I [Propionibacterium acnes].	25.26	384	227	14	35	388	237	590	1e-13	83.6
rs:WP_046746464	DNA topoisomerase I [Microbacterium sp. Ag1].	28.84	319	174	12	51	356	268	546	1e-13	83.6
rs:WP_047521580	DNA topoisomerase I [Microbacterium sp. ZOR0019].	28.22	326	179	11	45	356	262	546	1e-13	83.6
rs:WP_037348525	DNA topoisomerase I [Selenomonas sp. F0473].	25.06	427	260	13	50	457	255	640	1e-13	83.6
rs:WP_025090185	DNA topoisomerase I [Ochrobactrum intermedium].	26.98	430	242	17	60	452	241	635	1e-13	83.6
rs:WP_002815000	DNA topoisomerase I [Campylobacter coli].	25.35	426	246	17	47	450	225	600	1e-13	83.6
tr:A0A0B8TY06_LACCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	25.06	411	235	19	65	452	72	432	1e-13	83.2
rs:WP_040966852	DNA topoisomerase I [Corynebacterium glutamicum].	24.71	340	209	9	31	354	259	567	1e-13	83.6
rs:WP_002517152	DNA topoisomerase I [Propionibacterium acnes].	25.26	384	227	14	35	388	237	590	1e-13	83.6
rs:WP_021268964	DNA topoisomerase I [Mycobacterium abscessus].	26.12	379	231	11	41	399	258	607	1e-13	83.6
rs:WP_003045441	DNA topoisomerase III [Streptococcus canis].	25.85	325	203	12	67	385	267	559	1e-13	83.2
rs:WP_010418604	DNA topoisomerase I [Leptospira inadai].	25.00	400	236	11	74	449	249	608	1e-13	83.2
rs:WP_036334010	DNA topoisomerase I [Modestobacter sp. KNN45-2b].	26.06	353	216	11	42	377	284	608	1e-13	83.6
rs:WP_008510669	DNA topoisomerase I [Brucella inopinata].	26.44	416	240	15	70	452	253	635	1e-13	83.6
rs:WP_012566718	DNA topoisomerase I [Rhodospirillum centenum].	26.01	446	256	16	47	454	233	642	1e-13	83.6
rs:WP_008424783	DNA topoisomerase I [Clostridium sp. Maddingley MBC34-26].	24.39	410	246	15	66	454	242	608	1e-13	83.6
rs:WP_010701167	DNA topoisomerase I [Bartonella bovis].	26.25	419	246	17	67	452	248	636	1e-13	83.6
tr:D6LRZ3_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.68	416	239	15	70	452	262	644	1e-13	83.6
rs:WP_014941198	DNA topoisomerase I [Mycobacterium indicus pranii].	25.00	380	233	11	41	399	271	619	1e-13	83.6
rs:WP_014378962	DNA topoisomerase I [Mycobacterium intracellulare].	25.26	380	232	11	41	399	271	619	1e-13	83.6
rs:WP_024038270	DNA topoisomerase [Intestinibacter bartlettii].	23.53	408	245	13	68	454	247	608	1e-13	83.6
tr:B9YAX6_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.13	467	259	14	47	451	227	655	1e-13	83.2
rs:WP_022595650	DNA topoisomerase 1 [Vibrio nigripulchritudo].	26.56	320	190	10	77	386	291	575	1e-13	83.6
rs:WP_004406549	topoisomerase I [Vibrio nigripulchritudo].	26.56	320	190	10	77	386	291	575	1e-13	83.6
rs:WP_002529762	MULTISPECIES: DNA topoisomerase I [Propionibacterium].	25.26	384	227	14	35	388	237	590	1e-13	83.6
rs:WP_048240953	DNA topoisomerase I [Citrobacter freundii].	26.06	376	235	12	77	446	284	622	1e-13	83.6
rs:WP_019165481	DNA topoisomerase I [Staphylococcus delphini].	22.46	423	267	15	49	452	226	606	1e-13	83.2
rs:WP_005611954	topoisomerase I [Actinobacillus pleuropneumoniae].	25.30	411	254	16	47	446	261	629	1e-13	83.6
rs:WP_025296797	DNA topoisomerase I [Trueperella pyogenes].	26.70	352	203	13	27	358	240	556	1e-13	83.6
rs:WP_047976142	DNA topoisomerase I [[Actinobacillus] muris].	24.87	378	237	14	77	446	290	628	1e-13	83.6
rs:WP_024963976	DNA topoisomerase I [Trueperella pyogenes].	26.70	352	203	13	27	358	240	556	1e-13	83.6
gp:CP006897_535	DNA topoisomerase I [Brucella ceti TE10759-12]	26.68	416	239	15	70	452	262	644	1e-13	83.6
rs:WP_002917004	DNA topoisomerase I, partial [Campylobacter jejuni].	25.35	434	251	18	47	458	225	607	1e-13	83.2
rs:WP_002525218	MULTISPECIES: DNA topoisomerase I [Propionibacterium].	25.26	384	227	14	35	388	237	590	1e-13	83.6
rs:WP_016247142	DNA topoisomerase 1 [Escherichia coli].	25.80	376	236	12	77	446	284	622	1e-13	83.6
rs:WP_003840713	MULTISPECIES: DNA topoisomerase I subunit omega [Enterobacteriaceae].	26.06	376	235	12	77	446	284	622	1e-13	83.6
tr:K1Y7J1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.08	481	296	14	1	451	171	607	1e-13	83.2
rs:WP_005600888	topoisomerase I [Actinobacillus pleuropneumoniae].	25.30	411	254	16	47	446	261	629	1e-13	83.6
rs:WP_005604172	topoisomerase I [Actinobacillus pleuropneumoniae].	25.30	411	254	16	47	446	261	629	1e-13	83.6
rs:WP_027173538	DNA topoisomerase I [Methylobacterium sp. 10].	26.45	431	243	15	57	452	243	634	1e-13	83.6
rs:WP_023853733	DNA topoisomerase I [Candidatus Pelagibacter ubique].	24.69	409	241	14	77	454	260	632	1e-13	83.6
rs:WP_005074608	topoisomerase I [Shigella flexneri].	26.06	376	235	12	77	446	284	622	1e-13	83.6
rs:WP_019676957	topoisomerase I [Rheinheimera perlucida].	25.63	355	221	9	42	386	245	566	1e-13	83.6
rs:WP_032590264	DNA topoisomerase I [Campylobacter jejuni].	25.35	426	246	17	47	450	225	600	1e-13	83.2
rs:XP_002058130	GJ15664 [Drosophila virilis].	25.14	354	222	13	37	382	255	573	1e-13	83.6
rs:WP_022592886	DNA topoisomerase 1 [Vibrio nigripulchritudo].	26.88	320	189	10	77	386	291	575	1e-13	83.6
rs:WP_006119337	topoisomerase I [Pantoea stewartii].	25.70	393	232	14	77	452	284	633	1e-13	83.6
rs:WP_034266482	DNA topoisomerase I [Actinospica robiniae].	26.88	320	184	12	77	379	300	586	1e-13	83.6
rs:WP_038324611	DNA topoisomerase I [bacterium MS4].	23.54	480	258	18	35	449	213	648	1e-13	83.2
rs:WP_000520426	topoisomerase I [Vibrio cholerae].	26.77	381	225	15	77	446	292	629	1e-13	83.6
rs:WP_014517394	DNA topoisomerase I [Brucella melitensis].	26.43	420	237	16	70	454	253	635	1e-13	83.6
rs:WP_023031440	DNA topoisomerase I [Propionibacterium sp. KPL2008].	25.26	384	227	14	35	388	237	590	1e-13	83.6
rs:WP_025065595	DNA topoisomerase I [Prevotella enoeca].	26.15	260	162	7	77	334	252	483	1e-13	83.6
rs:WP_024321098	DNA topoisomerase I [Rhizobium leguminosarum].	25.06	439	266	15	47	452	230	638	1e-13	83.6
rs:WP_014991454	topoisomerase I [Actinobacillus suis].	25.06	411	255	16	47	446	261	629	1e-13	83.6
rs:WP_012626533	DNA topoisomerase I [Cyanothece sp. PCC 7425].	23.54	412	264	12	40	439	237	609	1e-13	83.2
rs:WP_000520427	topoisomerase I [Vibrio cholerae].	26.77	381	225	15	77	446	292	629	1e-13	83.6
rs:XP_002562369	Pc18g05420 [Penicillium rubens Wisconsin 54-1255].	24.27	342	192	8	41	359	261	558	1e-13	83.2
rs:XP_001642518	hypothetical protein Kpol_340p7 [Vanderwaltozyma polyspora DSM 70294].	26.79	321	184	11	56	357	296	584	1e-13	83.2
rs:WP_023860402	topoisomerase IA [Lactobacillus equi].	24.01	429	277	13	27	430	249	653	1e-13	83.6
rs:WP_011042034	topoisomerase I [Colwellia psychrerythraea].	25.75	400	247	15	57	446	269	628	1e-13	83.6
rs:WP_027097528	DNA topoisomerase I [Clostridium paraputrificum].	23.29	425	269	10	47	454	224	608	1e-13	83.2
rs:WP_043696433	DNA topoisomerase I [Luteibacter sp. 9133].	26.42	386	227	14	44	405	232	584	1e-13	83.6
rs:WP_002518689	DNA topoisomerase I [Propionibacterium acnes].	25.26	384	227	14	35	388	237	590	1e-13	83.6
rs:WP_048413522	DNA topoisomerase I [Chromobacterium sp. LK11].	23.27	477	266	14	49	459	233	675	1e-13	83.2
rs:WP_006468939	MULTISPECIES: DNA topoisomerase I [Ochrobactrum].	26.98	430	242	17	60	452	241	635	1e-13	83.6
gp:CP007694_557	DNA topoisomerase I [Brucella suis bv. 2]	26.68	416	239	15	70	452	262	644	1e-13	83.6
gpu:CP007696_557	DNA topoisomerase I [Brucella suis bv. 2]	26.68	416	239	15	70	452	262	644	1e-13	83.6
rs:WP_031693912	DNA topoisomerase I [Pseudomonas aeruginosa].	24.39	410	247	13	74	459	260	630	1e-13	83.2
rs:WP_044068334	DNA topoisomerase I [Propionibacterium acnes].	25.26	384	227	14	35	388	237	590	1e-13	83.6
rs:WP_002545594	DNA topoisomerase I [Propionibacterium acnes].	25.26	384	227	14	35	388	237	590	1e-13	83.6
rs:YP_001701242	DNA topoisomerase I (Omega-protein) [Mycobacterium abscessus].	26.12	379	231	11	41	399	258	607	1e-13	83.6
rs:WP_013278603	DNA topoisomerase I [Acetohalobium arabaticum].	22.15	438	275	11	40	456	218	610	1e-13	83.2
rs:WP_006611233	DNA topoisomerase I [Bradyrhizobium sp. ORS 285].	25.64	429	250	15	60	454	243	636	1e-13	83.6
rs:WP_018355602	topoisomerase I [[Pasteurella] pneumotropica].	24.33	411	250	16	46	446	269	628	1e-13	83.6
rs:WP_015257273	DNA topoisomerase I [Thioalkalivibrio nitratireducens].	28.36	342	184	13	31	350	221	523	1e-13	83.6
rs:WP_006418410	DNA topoisomerase I [Eremococcus coleocola].	23.39	466	275	16	18	452	188	602	1e-13	83.2
rs:WP_047553395	DNA topoisomerase I [Rhizobium leguminosarum].	25.00	440	266	14	47	452	230	639	1e-13	83.6
rs:XP_001354695	GA17464 [Drosophila pseudoobscura pseudoobscura].	25.07	351	216	14	39	379	258	571	1e-13	83.6
rs:WP_025567135	DNA topoisomerase I [Gammaproteobacteria bacterium SCGC AAA003-E02].	22.68	463	303	13	1	446	210	634	1e-13	83.6
rs:WP_011896614	DNA topoisomerase I [Corynebacterium glutamicum].	24.71	340	209	9	31	354	259	567	1e-13	83.6
rs:WP_009132458	DNA topoisomerase I [Bacteroides oleiciplenus].	25.67	300	185	7	40	334	216	482	1e-13	83.2
rs:WP_033741827	DNA topoisomerase I [Pantoea stewartii].	25.70	393	232	14	77	452	284	633	1e-13	83.6
tr:K1Q3B4_CRAGI	SubName: Full=DNA topoisomerase 3-beta-1 {ECO:0000313|EMBL:EKC25894.1};	24.37	439	256	16	40	453	257	644	1e-13	83.6
rs:WP_045529134	DNA topoisomerase I [Clavibacter michiganensis].	27.69	372	215	16	30	379	239	578	1e-13	83.6
rs:XP_011443037	PREDICTED: DNA topoisomerase 3-beta-1-like [Crassostrea gigas].	23.71	447	249	15	40	453	262	649	1e-13	83.6
rs:WP_004690220	MULTISPECIES: DNA topoisomerase I [Brucella].	26.68	416	239	15	70	452	253	635	1e-13	83.6
rs:WP_032449162	DNA topoisomerase I [Brucella suis].	26.68	416	239	15	70	452	253	635	1e-13	83.6
rs:WP_018494099	DNA topoisomerase I [Rhizobium leguminosarum].	25.06	439	266	15	47	452	230	638	1e-13	83.6
rs:WP_032592152	DNA topoisomerase I [Campylobacter jejuni].	25.35	426	246	17	47	450	225	600	1e-13	83.2
rs:WP_012243411	DNA topoisomerase I [Brucella suis].	26.68	416	239	15	70	452	253	635	1e-13	83.6
rs:WP_046431670	DNA topoisomerase I [Ruminococcus sp. A254.MGS-108].	24.03	466	263	17	40	449	218	648	1e-13	83.2
rs:WP_014668030	topoisomerase I [Pasteurella multocida].	24.01	379	239	13	77	446	290	628	1e-13	83.6
rs:WP_004424930	DNA topoisomerase I [Mycoplasma auris].	24.93	381	204	15	92	449	270	591	1e-13	83.2
tr:A0A0F6ILM6_BRUSS	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:ENR18375.1};	26.68	416	239	15	70	452	262	644	1e-13	83.6
rs:WP_005773509	DNA topoisomerase I [Bartonella elizabethae].	27.02	433	246	18	55	452	239	636	1e-13	83.6
rs:WP_002678704	DNA topoisomerase I [Treponema denticola].	24.14	435	270	15	36	452	232	624	1e-13	83.2
rs:WP_021148177	DNA topoisomerase I [Veillonella parvula].	23.24	426	266	13	47	454	295	677	1e-13	83.2
rs:WP_047263090	DNA topoisomerase I [Corynebacterium mustelae].	24.46	323	205	8	41	351	259	554	1e-13	83.6
rs:WP_021552277	DNA topoisomerase 1 [Escherichia coli].	25.53	380	232	13	77	446	284	622	1e-13	83.6
rs:WP_041438846	DNA topoisomerase I, partial [Synechococcus sp. JA-3-3Ab].	24.93	349	221	9	41	379	253	570	1e-13	83.6
rs:WP_034086253	DNA topoisomerase I [Pseudomonas aeruginosa].	24.09	411	247	14	74	459	260	630	1e-13	83.2
rs:WP_012953898	DNA topoisomerase I [Candidatus Atelocyanobacterium thalassa].	26.12	356	226	11	41	387	249	576	1e-13	83.6
rs:WP_032839013	DNA topoisomerase I [Bacteroides finegoldii].	26.80	291	179	8	47	334	223	482	1e-13	83.2
rs:WP_032451138	DNA topoisomerase I [Brucella sp. 04-5288].	26.68	416	239	15	70	452	253	635	1e-13	83.6
rs:WP_007321541	DNA topoisomerase I [Gordonia araii].	26.03	365	219	12	41	386	265	597	1e-13	83.6
rs:WP_024992857	hypothetical protein, partial [Prevotella amnii].	31.67	221	132	9	232	446	6	213	1e-13	80.5
rs:WP_033982829	DNA topoisomerase I [Pseudomonas aeruginosa].	24.69	405	254	13	74	459	260	632	1e-13	83.2
rs:WP_003855832	MULTISPECIES: DNA topoisomerase I [Corynebacterium].	24.71	340	209	9	31	354	259	567	1e-13	83.6
rs:WP_045355889	DNA topoisomerase I [Enterobacter asburiae].	26.05	380	230	14	77	446	284	622	1e-13	83.2
tr:W6RSU7_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.06	439	266	15	47	452	231	639	1e-13	83.6
rs:WP_035002902	DNA topoisomerase I [Corynebacterium jeikeium].	25.08	327	204	9	41	354	265	563	1e-13	83.6
rs:WP_016858466	DNA topoisomerase I [Fischerella muscicola].	23.29	425	264	14	40	443	241	624	1e-13	83.2
rs:WP_039663180	DNA topoisomerase I [Trueperella pyogenes].	26.70	352	203	13	27	358	240	556	1e-13	83.6
rs:WP_001734569	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	28.17	284	165	10	77	356	284	532	1e-13	82.8
rs:WP_013010160	DNA topoisomerase I [Denitrovibrio acetiphilus].	25.87	429	261	13	40	452	219	606	1e-13	83.2
rs:WP_022551015	DNA topoisomerase 1 [Vibrio nigripulchritudo].	26.56	320	190	10	77	386	291	575	1e-13	83.2
rs:WP_039249168	DNA topoisomerase I [Clostridium novyi].	23.96	434	259	17	47	457	226	611	1e-13	83.2
rs:WP_045400177	DNA topoisomerase I [Enterobacter asburiae].	26.05	380	230	14	77	446	284	622	1e-13	83.2
rs:WP_047071578	DNA topoisomerase I [Enterobacter asburiae].	26.05	380	230	14	77	446	284	622	1e-13	83.2
rs:WP_024314695	MULTISPECIES: DNA topoisomerase I [Rhizobium].	25.06	439	266	15	47	452	230	638	1e-13	83.2
rs:WP_012101804	DNA topoisomerase I [Clostridium kluyveri].	24.54	432	255	16	47	454	226	610	1e-13	83.2
rs:WP_014391063	topoisomerase I [Pasteurella multocida].	24.01	379	239	13	77	446	290	628	1e-13	83.2
rs:WP_006712555	topoisomerase I [Vibrio ichthyoenteri].	26.41	337	193	11	68	386	275	574	1e-13	83.2
rs:WP_028124627	DNA topoisomerase I [Eremococcus coleocola].	23.39	466	275	16	18	452	188	602	1e-13	83.2
rs:WP_006642029	DNA topoisomerase I [Brucella ceti].	26.68	416	239	15	70	452	253	635	1e-13	83.2
rs:WP_004598104	DNA topoisomerase I [Halorubrum distributum].	24.75	408	234	13	86	454	297	670	1e-13	83.2
rs:WP_018106628	hypothetical protein [Porphyromonas bennonis].	27.61	268	165	7	68	334	241	480	1e-13	83.2
rs:WP_037543181	DNA topoisomerase I [Staphylococcus pseudintermedius].	22.46	423	267	14	49	452	226	606	1e-13	83.2
rs:WP_019490681	DNA topoisomerase I [Calothrix sp. PCC 7103].	25.26	380	232	12	41	401	249	595	2e-13	83.2
rs:WP_039444195	DNA topoisomerase I [Vibrio navarrensis].	25.14	358	221	10	40	386	253	574	2e-13	83.2
rs:WP_006698006	DNA topoisomerase I [Rhizobium lupini].	25.45	444	258	16	47	452	230	638	2e-13	83.2
rs:WP_002534294	DNA topoisomerase I [Propionibacterium acnes].	25.26	384	227	14	35	388	237	590	2e-13	83.6
rs:WP_029057500	DNA topoisomerase I [Stappia stellulata].	26.91	431	226	16	60	446	243	628	2e-13	83.2
rs:WP_008295426	topoisomerase I [Congregibacter litoralis].	25.83	391	239	14	74	452	292	643	2e-13	83.2
rs:WP_000520439	topoisomerase I [Vibrio mimicus].	25.82	395	233	15	69	446	278	629	2e-13	83.2
rs:WP_016825233	DNA topoisomerase I [Streptomyces viridosporus].	25.91	328	194	11	42	354	264	557	2e-13	83.6
rs:WP_003863283	MULTISPECIES: DNA topoisomerase I [Corynebacterium].	24.71	340	209	9	31	354	259	567	2e-13	83.6
rs:WP_001726005	DNA topoisomerase 1 [Escherichia coli].	25.93	378	233	13	77	446	284	622	2e-13	83.2
rs:WP_020802463	DNA topoisomerase I [Klebsiella pneumoniae].	27.11	380	226	15	77	446	284	622	2e-13	83.2
tr:Q2JWS9_SYNJA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.93	349	221	9	41	379	253	570	2e-13	83.2
rs:WP_022610573	DNA topoisomerase 1 [Vibrio nigripulchritudo].	26.88	320	189	10	77	386	291	575	2e-13	83.2
rs:WP_038272748	DNA topoisomerase I, partial [actinobacterium acAMD-2].	26.93	375	226	15	31	387	245	589	2e-13	83.2
rs:WP_001361672	DNA topoisomerase 1 [Escherichia coli].	26.32	380	229	14	77	446	284	622	2e-13	83.2
rs:WP_037503922	DNA topoisomerase I, partial [Sphingomonas jaspsi].	26.56	433	256	15	43	452	224	617	2e-13	83.2
rs:WP_002902895	DNA topoisomerase I [Campylobacter jejuni].	25.35	426	246	17	47	450	225	600	2e-13	83.2
rs:WP_022935905	DNA topoisomerase I [Mycoplasma orale].	24.70	413	230	15	61	450	244	598	2e-13	83.2
rs:WP_010685456	DNA topoisomerase I [Methylobacterium mesophilicum].	26.06	449	243	17	43	452	236	634	2e-13	83.2
rs:WP_045620487	MULTISPECIES: DNA topoisomerase I [Enterobacter cloacae complex].	26.05	380	230	14	77	446	284	622	2e-13	83.2
rs:WP_016534517	DNA topoisomerase I subunit omega [Pasteurella multocida].	24.01	379	239	13	77	446	290	628	2e-13	83.2
rs:WP_020965885	DNA topoisomerase I [Treponema pedis].	25.24	420	256	13	50	452	253	631	2e-13	83.2
tr:K2A4U6_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.53	510	280	20	6	450	199	663	2e-13	83.2
rs:WP_002812170	DNA topoisomerase I [Campylobacter coli].	25.35	426	246	17	47	450	225	600	2e-13	83.2
tr:C9KRB4_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.80	291	179	8	47	334	233	492	2e-13	83.2
rs:WP_000520437	topoisomerase I [Vibrio mimicus].	25.82	395	233	15	69	446	278	629	2e-13	83.2
rs:WP_022578139	topoisomerase I [Vibrio mimicus].	25.82	395	233	15	69	446	278	629	2e-13	83.2
rs:WP_034035504	DNA topoisomerase I [Pseudomonas aeruginosa].	24.69	405	254	13	74	459	260	632	2e-13	83.2
rs:WP_001725981	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	28.17	284	165	10	77	356	284	532	2e-13	82.8
rs:WP_047974486	DNA topoisomerase I, partial [Fructobacillus sp. EFB-N1].	24.59	431	263	15	41	452	237	624	2e-13	83.2
rs:WP_030461460	DNA topoisomerase I [Kitasatospora sp. NRRL B-11411].	26.87	294	164	12	77	354	300	558	2e-13	83.2
rs:XP_002099887	GE16470 [Drosophila yakuba].	23.67	376	232	13	37	394	256	594	2e-13	83.2
rs:WP_032504065	DNA topoisomerase I [Propionibacterium acnes].	24.80	383	234	13	30	388	238	590	2e-13	83.2
rs:WP_037866264	DNA topoisomerase I [Streptomyces sp. NRRL S-1868].	25.30	328	196	11	42	354	267	560	2e-13	83.2
rs:WP_041322328	DNA topoisomerase I [Mycobacterium leprae].	26.46	378	230	12	41	399	278	626	2e-13	83.2
rs:WP_047578099	DNA topoisomerase I, partial [Methylobacterium sp. ZNC0032].	26.86	458	252	18	34	454	225	636	2e-13	83.2
rs:WP_038846354	DNA topoisomerase I [Campylobacter coli].	25.23	432	251	17	41	450	219	600	2e-13	83.2
rs:XP_012811616	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Xenopus (Silurana) tropicalis].	23.35	454	265	19	29	453	115	514	2e-13	83.2
rs:WP_031571001	DNA topoisomerase I [Rheinheimera texasensis].	26.30	422	251	16	40	446	243	619	2e-13	83.2
rs:WP_002791644	DNA topoisomerase I [Campylobacter coli].	25.23	432	251	17	41	450	219	600	2e-13	83.2
rs:WP_047002751	DNA topoisomerase I [Erythrobacter sp. KA37].	25.47	369	215	11	18	371	190	513	2e-13	83.2
rs:WP_043959647	DNA topoisomerase I [Lysobacter sp. A03].	28.29	304	171	11	69	354	255	529	2e-13	83.2
rs:WP_020095334	DNA topoisomerase I [Methylobacterium sp. 285MFTsu5.1].	26.01	446	247	16	43	452	236	634	2e-13	83.2
rs:WP_012311849	DNA topoisomerase I [Escherichia coli].	26.32	380	229	14	77	446	284	622	2e-13	83.2
rs:WP_019888308	DNA topoisomerase I [Streptomyces purpureus].	27.65	293	163	11	77	354	298	556	2e-13	83.2
rs:WP_018484047	DNA topoisomerase I [Rhizobium leguminosarum].	25.06	439	266	15	47	452	230	638	2e-13	83.2
rs:WP_022863555	DNA topoisomerase I [Corynebacterium massiliense].	25.84	356	208	14	47	378	274	597	2e-13	83.2
rs:WP_018217137	DNA topoisomerase I [Salinispora pacifica].	25.77	326	193	12	42	351	261	553	2e-13	83.2
rs:WP_025248461	DNA topoisomerase I [Pasteurella multocida].	24.01	379	239	13	77	446	290	628	2e-13	83.2
rs:WP_041289732	DNA topoisomerase I [Kribbella flavida].	28.97	290	163	13	77	354	283	541	2e-13	83.2
rs:WP_040199198	DNA topoisomerase I [Geoalkalibacter subterraneus].	27.59	406	240	16	66	454	255	623	2e-13	83.2
rs:WP_046186104	DNA topoisomerase I [Mycobacterium nebraskense].	25.00	380	233	11	41	399	271	619	2e-13	83.2
rs:WP_017991042	DNA topoisomerase I [Rhizobium leguminosarum].	24.83	439	267	15	47	452	230	638	2e-13	83.2
rs:WP_009946467	DNA topoisomerase I [Saccharopolyspora erythraea].	26.80	388	219	14	36	399	251	597	2e-13	83.2
rs:WP_004347969	DNA topoisomerase I [Pseudomonas aeruginosa].	24.69	405	254	13	74	459	260	632	2e-13	82.8
rs:WP_031670651	DNA topoisomerase I [Pseudomonas aeruginosa].	24.82	411	246	13	74	459	260	632	2e-13	82.8
tr:G3NI54_GASAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.13	441	261	15	40	453	256	645	2e-13	83.2
rs:WP_008366091	DNA topoisomerase I [Halorubrum litoreum].	24.75	408	234	13	86	454	297	670	2e-13	83.2
rs:WP_023312071	MULTISPECIES: DNA topoisomerase 1 [Enterobacter].	26.05	380	230	14	77	446	284	622	2e-13	83.2
rs:WP_011503433	DNA topoisomerase I [Rhodopseudomonas palustris].	25.41	425	255	13	61	454	244	637	2e-13	83.2
rs:WP_018509290	DNA topoisomerase I [Thiobacillus thioparus].	24.05	420	257	13	51	454	231	604	2e-13	83.2
rs:WP_032930423	DNA topoisomerase I [Mesorhizobium loti].	26.39	451	254	21	41	452	224	635	2e-13	83.2
tr:E1YHR2_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.47	425	264	16	43	449	221	606	2e-13	83.2
rs:WP_021901316	DNA topoisomerase [Coprobacillus sp. CAG:698].	24.62	390	232	13	77	449	255	599	2e-13	82.8
rs:WP_044135611	DNA topoisomerase III, partial [Bacteroides fragilis].	30.69	189	125	5	210	396	4	188	2e-13	80.9
rs:WP_047510011	DNA topoisomerase I [Rhizobium sp. YR528].	25.11	442	262	15	47	452	230	638	2e-13	83.2
tr:A0A0B7CZP6_9PSEU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.12	356	214	11	40	377	290	614	2e-13	83.2
rs:WP_005051207	DNA topoisomerase I [Microbacterium laevaniformans].	28.24	347	197	12	45	377	268	576	2e-13	83.2
rs:WP_021199119	DNA topoisomerase I [Microbacterium maritypicum].	28.22	326	179	11	45	356	262	546	2e-13	83.2
rs:WP_042198471	DNA topoisomerase I, partial [Kibdelosporangium sp. MJ126-NF4].	26.12	356	214	11	40	377	248	572	2e-13	83.2
rs:WP_042648448	DNA topoisomerase I [Aeromonas media].	24.29	420	260	13	49	452	259	636	2e-13	83.2
rs:WP_014404407	DNA topoisomerase I [Frateuria aurantia].	27.76	353	204	12	50	380	238	561	2e-13	83.2
rs:WP_000520441	topoisomerase I [Vibrio sp. RC586].	26.33	395	231	16	69	446	278	629	2e-13	83.2
sp:TOP1_MYCLE	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	26.46	378	230	12	41	399	272	620	2e-13	83.2
rs:WP_032853999	DNA topoisomerase I [Pasteurella multocida].	24.01	379	239	13	77	446	290	628	2e-13	83.2
rs:WP_002841473	DNA topoisomerase I [Campylobacter coli].	25.23	432	251	17	41	450	219	600	2e-13	83.2
rs:WP_008757996	DNA topoisomerase I [Rhodobacteraceae bacterium KLH11].	26.20	458	250	18	47	454	231	650	2e-13	83.2
rs:WP_030648197	MULTISPECIES: DNA topoisomerase I [Streptomyces].	26.96	293	165	11	77	354	298	556	2e-13	83.2
rs:WP_001722109	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	28.17	284	165	10	77	356	284	532	2e-13	82.8
rs:WP_005751468	topoisomerase I [Pasteurella multocida].	24.01	379	239	13	77	446	290	628	2e-13	83.2
rs:WP_011651394	DNA topoisomerase I [Rhizobium leguminosarum].	24.83	439	267	15	47	452	230	638	2e-13	83.2
rs:WP_002878738	DNA topoisomerase I [Campylobacter jejuni].	25.35	434	251	18	47	458	225	607	2e-13	82.8
rs:WP_009384973	topoisomerase I [Vibrio sp. N418].	27.00	337	191	11	68	386	275	574	2e-13	83.2
rs:WP_035253559	DNA topoisomerase I [Agrococcus lahaulensis].	26.14	329	197	9	41	354	251	548	2e-13	83.2
rs:WP_019793429	hypothetical protein, partial [Streptococcus sobrinus].	25.93	297	173	10	166	452	28	287	2e-13	81.6
rs:WP_008023233	DNA topoisomerase I [Bacteroides xylanisolvens].	25.71	315	185	8	36	334	201	482	2e-13	83.2
rs:WP_000520440	topoisomerase I [Vibrio mimicus].	25.82	395	233	15	69	446	278	629	2e-13	83.2
rs:WP_042669667	DNA topoisomerase I [Methylobacterium sp. B34].	26.01	446	247	16	43	452	236	634	2e-13	83.2
rs:WP_041662546	DNA topoisomerase I [Streptomyces venezuelae].	26.96	293	165	11	77	354	299	557	2e-13	83.2
tr:W1W5N7_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.89	427	262	14	47	454	298	680	2e-13	83.2
rs:WP_011562173	MULTISPECIES: DNA topoisomerase I [Mycobacterium].	26.24	362	214	12	60	399	305	635	2e-13	83.2
tr:A0A0F6H0E3_PASMD	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EJZ80223.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EJZ80223.1};	24.01	379	239	13	77	446	296	634	2e-13	83.2
tr:A0A0F5QR70_9GAMM	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KKC43186.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KKC43186.1}; Flags: Fragment;	28.33	300	173	12	40	334	266	528	2e-13	82.8
tr:N6V4J9_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.06	439	267	13	47	452	231	640	2e-13	83.2
rs:WP_034566021	DNA topoisomerase I [Helicobacter bilis].	23.78	429	261	15	41	450	222	603	2e-13	83.2
rs:WP_013164497	DNA topoisomerase I [Desulfurivibrio alkaliphilus].	24.77	444	281	17	31	452	213	625	2e-13	83.2
rs:WP_002789823	DNA topoisomerase I [Campylobacter coli].	25.23	432	251	17	41	450	219	600	2e-13	82.8
rs:WP_002842632	DNA topoisomerase I [Campylobacter coli].	25.23	432	251	17	41	450	219	600	2e-13	82.8
rs:WP_041971679	DNA topoisomerase I [Geobacter sp. OR-1].	25.12	426	255	15	43	446	228	611	2e-13	83.2
tr:A0A0D1K8U8_9LACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.96	197	127	4	57	249	269	460	2e-13	82.4
rs:WP_001347791	DNA topoisomerase 1 [Escherichia coli].	25.80	376	236	12	77	446	284	622	2e-13	83.2
rs:WP_001573409	DNA topoisomerase 1 [Escherichia coli].	25.80	376	236	12	77	446	284	622	2e-13	83.2
rs:WP_007344964	DNA topoisomerase I [Halorubrum terrestre].	24.75	408	234	13	86	454	297	670	2e-13	83.2
rs:WP_010340715	DNA topoisomerase I subunit omega [Escherichia albertii].	25.80	376	236	12	77	446	284	622	2e-13	83.2
rs:WP_008287467	DNA topoisomerase I [Hydrogenivirga sp. 128-5-R1-1].	26.23	366	208	11	32	377	192	515	2e-13	82.8
tr:C0S9B3_PARBP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.87	317	181	9	73	369	294	576	2e-13	82.8
rs:WP_034489568	DNA topoisomerase I [Agrobacterium rhizogenes].	25.00	440	266	14	47	452	230	639	2e-13	83.2
tr:D2PW45_KRIFD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.97	290	163	13	77	354	305	563	2e-13	83.2
rs:WP_047093970	DNA topoisomerase I [Erythrobacter marinus].	26.08	418	256	11	1	400	173	555	2e-13	83.2
rs:XP_003138981	DNA topoisomerase III [Loa loa].	25.00	356	226	9	40	388	284	605	2e-13	83.2
rs:WP_027573622	DNA topoisomerase I [Bradyrhizobium sp. WSM1743].	24.65	426	252	13	61	452	244	634	2e-13	83.2
rs:WP_028643525	DNA topoisomerase I [Nocardioides sp. URHA0020].	27.36	329	191	12	42	356	257	551	2e-13	83.2
rs:WP_022249372	DNA topoisomerase [Eubacterium sp. CAG:274].	23.70	422	267	11	48	454	228	609	2e-13	82.8
rs:WP_024933161	DNA topoisomerase I [Clostridium botulinum].	24.32	407	234	16	74	454	252	610	2e-13	82.8
rs:WP_042029466	DNA topoisomerase 1 [Escherichia coli].	26.32	380	229	14	77	446	284	622	2e-13	83.2
rs:XP_005745890	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X1 [Pundamilia nyererei].	22.68	441	261	15	40	453	261	648	2e-13	83.2
tr:A0A0D1WU41_9EURO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.48	379	239	10	41	401	261	606	2e-13	82.8
rs:WP_005394690	DNA topoisomerase I [Corynebacterium glucuronolyticum].	24.59	362	234	9	36	386	247	580	2e-13	83.2
rs:WP_020000196	MULTISPECIES: DNA topoisomerase I [Desulfovibrio].	25.30	419	236	15	66	452	243	616	2e-13	83.2
tr:H4J7F7_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.41	321	187	12	77	386	284	569	2e-13	82.8
rs:WP_048315186	DNA topoisomerase I [Parabacteroides goldsteinii].	26.96	345	211	13	65	384	239	567	2e-13	83.2
rs:WP_037153652	DNA topoisomerase I [Rhizobium freirei].	25.06	439	267	13	47	452	230	639	2e-13	83.2
rs:XP_001386841	DNA topoisomerase [Scheffersomyces stipitis CBS 6054].	25.14	358	216	11	37	377	253	575	2e-13	82.8
rs:WP_002884212	DNA topoisomerase I [Campylobacter jejuni].	25.35	426	246	17	47	450	225	600	2e-13	82.8
tr:T0UGY1_LEUMC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.34	415	232	18	66	452	282	642	2e-13	82.8
rs:WP_029258706	DNA topoisomerase I [Microbacterium sp. Cr-K29].	28.22	326	179	11	45	356	262	546	2e-13	83.2
rs:WP_002521095	DNA topoisomerase I [Propionibacterium acnes].	25.07	383	233	13	30	388	238	590	2e-13	83.2
rs:WP_021875555	DNA topoisomerase [Clostridium chauvoei].	23.95	405	244	13	71	454	247	608	2e-13	82.8
rs:WP_029872825	DNA topoisomerase I [Rhizobium leguminosarum].	24.83	439	267	15	47	452	230	638	2e-13	83.2
rs:WP_029267263	DNA topoisomerase I [Microbacterium sp. Cr-K32].	28.22	326	179	11	45	356	262	546	2e-13	83.2
rs:WP_002873255	DNA topoisomerase I [Campylobacter jejuni].	25.35	426	246	17	47	450	225	600	2e-13	82.8
rs:WP_029473387	DNA topoisomerase I [Clostridiales bacterium VE202-08].	25.12	430	262	13	41	452	219	606	2e-13	82.8
rs:WP_030886590	DNA topoisomerase I [Streptomyces sp. NRRL F-5053].	25.30	328	196	11	42	354	267	560	2e-13	83.2
rs:WP_013562560	DNA topoisomerase I [Desulfurococcus mucosus].	26.52	313	187	11	74	377	294	572	2e-13	82.8
tr:A0A0D2I1P8_9EURO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.70	422	263	12	18	411	235	625	2e-13	82.8
rs:WP_007655144	DNA topoisomerase I [Parabacteroides goldsteinii].	26.96	345	211	13	65	384	239	567	2e-13	82.8
tr:L1MTZ4_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EKX94520.1};	30.19	212	129	6	221	425	12	211	2e-13	80.5
rs:WP_038625919	DNA topoisomerase I [Pantoea sp. PSNIH2].	26.09	391	233	15	77	452	281	630	2e-13	83.2
rs:WP_038851041	DNA topoisomerase I [Campylobacter coli].	25.23	432	251	17	41	450	219	600	2e-13	82.8
rs:XP_005745891	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X2 [Pundamilia nyererei].	22.68	441	261	15	40	453	263	650	2e-13	83.2
rs:WP_038647025	DNA topoisomerase I [Mesorhizobium huakuii].	26.39	451	254	21	41	452	224	635	2e-13	83.2
rs:WP_036431931	DNA topoisomerase I [Mycobacterium mageritense].	27.83	345	196	12	77	399	304	617	2e-13	83.2
rs:WP_026972497	DNA topoisomerase I [Aliagarivorans marinus].	25.00	420	268	13	35	446	249	629	2e-13	83.2
rs:WP_029520244	DNA topoisomerase I [Persephonella sp. IF05-L8].	23.82	361	222	10	40	385	216	538	2e-13	82.8
rs:WP_001422890	topoisomerase I [Escherichia coli].	25.80	376	236	12	77	446	284	622	2e-13	83.2
rs:WP_022460775	DNA topoisomerase [Alistipes putredinis CAG:67].	28.84	267	155	9	77	340	252	486	2e-13	82.8
rs:WP_004329382	DNA topoisomerase I [Alistipes putredinis].	28.84	267	155	9	77	340	252	486	2e-13	82.8
rs:WP_002798917	DNA topoisomerase I [Campylobacter coli].	25.23	432	251	17	41	450	219	600	2e-13	82.8
rs:WP_019858383	DNA topoisomerase I [Mesorhizobium loti].	26.39	451	254	21	41	452	224	635	2e-13	83.2
rs:WP_010909698	DNA topoisomerase I [Mesorhizobium loti].	26.39	451	254	21	41	452	224	635	2e-13	83.2
rs:WP_030817511	MULTISPECIES: DNA topoisomerase I [Streptomyces].	26.96	293	165	11	77	354	298	556	2e-13	83.2
rs:WP_018274720	topoisomerase I [Teredinibacter turnerae].	25.12	422	266	13	42	452	261	643	2e-13	83.2
tr:C4LLJ1_CORK4	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.32	366	229	9	31	378	257	592	2e-13	83.2
rs:WP_046012192	DNA topoisomerase I [Microbacterium sp. SA39].	27.87	348	187	12	31	356	249	554	2e-13	83.2
rs:WP_039774455	DNA topoisomerase I [Clostridium botulinum].	23.90	431	238	15	74	449	252	647	2e-13	82.8
rs:WP_002462101	topoisomerase I [Escherichia albertii].	25.80	376	236	12	77	446	284	622	2e-13	83.2
rs:WP_026773797	DNA topoisomerase I [Sediminibacterium sp. OR43].	26.30	308	188	9	36	339	214	486	2e-13	83.2
rs:WP_017304772	DNA topoisomerase I [Spirulina subsalsa].	25.07	359	229	8	41	391	249	575	2e-13	83.2
rs:XP_008546120	PREDICTED: DNA topoisomerase 3-beta-1 [Microplitis demolitor].	23.76	362	220	12	39	385	260	580	2e-13	83.2
rs:WP_044456500	DNA topoisomerase, partial [Bacillus subtilis].	29.95	217	137	5	52	264	264	469	2e-13	82.4
rs:WP_026197617	DNA topoisomerase I [Sciscionella marina].	26.84	339	204	11	30	354	259	567	2e-13	83.2
rs:WP_038841321	DNA topoisomerase I [Campylobacter coli].	25.00	432	252	17	41	450	219	600	2e-13	82.8
rs:WP_018692543	hypothetical protein [Algicola sagamiensis].	26.48	321	198	9	40	356	253	539	2e-13	83.2
rs:WP_025237092	DNA topoisomerase I [Escherichia albertii].	25.80	376	236	12	77	446	284	622	2e-13	83.2
gp:CP003183_2502	DNA topoisomerase I [Granulibacter bethesdensis CGDNIH2]	24.89	454	271	16	31	452	232	647	2e-13	83.2
rs:WP_038641850	DNA topoisomerase I [Pasteurella multocida].	24.01	379	239	13	77	446	290	628	2e-13	83.2
rs:WP_039749312	DNA topoisomerase I [Hassallia byssoidea].	26.12	291	176	7	50	335	222	478	2e-13	82.8
rs:WP_032591081	DNA topoisomerase I [Campylobacter jejuni].	25.35	426	246	17	47	450	225	600	2e-13	82.8
rs:WP_028050570	DNA topoisomerase I [Cellulomonas sp. URHD0024].	27.63	333	195	11	42	356	253	557	2e-13	83.2
rs:WP_007371932	topoisomerase I [Kosakonia radicincitans].	26.58	380	228	15	77	446	284	622	2e-13	82.8
rs:WP_001423441	topoisomerase I [Escherichia coli].	25.80	376	236	12	77	446	284	622	2e-13	82.8
rs:WP_020315918	DNA topoisomerase III, partial [Pseudomonas syringae].	40.23	87	52	0	61	147	267	353	2e-13	81.3
tr:A0A0E1QH36_CLOBO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.32	407	234	16	74	454	256	614	2e-13	82.8
rs:WP_002918791	DNA topoisomerase I [Campylobacter jejuni].	25.35	434	251	18	47	458	225	607	2e-13	82.8
rs:WP_002869687	DNA topoisomerase I [Campylobacter jejuni].	25.35	434	251	18	47	458	225	607	2e-13	82.8
rs:WP_041628935	DNA topoisomerase I [Corynebacterium kroppenstedtii].	24.32	366	229	9	31	378	268	603	2e-13	83.2
rs:WP_034984547	DNA topoisomerase I [Corynebacterium jeikeium].	26.46	325	202	11	41	354	265	563	2e-13	83.2
rs:WP_007566173	DNA topoisomerase I [Methylobacterium sp. GXF4].	26.19	443	250	16	43	452	236	634	2e-13	83.2
rs:WP_031138477	DNA topoisomerase I [Streptomyces xanthophaeus].	26.96	293	165	11	77	354	298	556	2e-13	83.2
rs:WP_002860825	DNA topoisomerase I [Campylobacter jejuni].	24.77	432	253	17	41	450	219	600	2e-13	82.8
rs:WP_002829326	DNA topoisomerase I [Campylobacter coli].	25.23	432	251	17	41	450	219	600	2e-13	82.8
rs:WP_003030107	DNA topoisomerase [Streptococcus anginosus].	24.57	346	221	11	59	397	263	575	2e-13	82.4
rs:WP_041129894	DNA topoisomerase I [Streptomyces vietnamensis].	26.96	293	165	11	77	354	299	557	2e-13	83.2
tr:A0A0A6KY88_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KHC37170.1};	26.41	337	201	10	56	378	275	578	2e-13	82.8
rs:WP_008751513	DNA topoisomerase I [Lachnoanaerobaculum saburreum].	22.78	439	280	12	34	454	214	611	2e-13	82.8
rs:WP_040991531	MULTISPECIES: DNA topoisomerase I [Vibrio].	26.68	431	245	17	42	446	242	627	2e-13	82.8
tr:A0A0D2LUA1_9CHLO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.36	220	119	5	166	383	67	256	2e-13	80.5
rs:WP_026283306	DNA topoisomerase I [Rhizobium sp. 2MFCol3.1].	25.11	442	262	15	47	452	230	638	2e-13	82.8
rs:WP_040075361	DNA topoisomerase I [Enterobacter cloacae].	26.32	380	229	14	77	446	284	622	2e-13	82.8
tr:M2X4Y3_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.36	330	195	10	41	354	247	544	2e-13	83.2
tr:Q6AGT6_LEIXX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.42	372	220	13	30	380	271	613	2e-13	83.2
rs:WP_028810409	DNA topoisomerase I [Streptomyces flavidovirens].	26.96	293	165	11	77	354	298	556	2e-13	83.2
rs:XP_004405235	PREDICTED: DNA topoisomerase 3-alpha [Odobenus rosmarus divergens].	26.08	372	208	13	112	455	350	682	2e-13	83.2
tr:G7XEX1_ASPKW	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.30	346	195	10	45	369	267	573	2e-13	82.8
rs:WP_040854215	DNA topoisomerase I [Nocardia niigatensis].	26.63	338	201	11	35	356	243	549	2e-13	82.8
rs:WP_031077547	DNA topoisomerase I [Streptomyces sp. NRRL S-118].	26.62	293	166	11	77	354	301	559	2e-13	82.8
rs:WP_022194818	DNA topoisomerase, partial [Clostridium sp. CAG:217].	25.34	292	178	9	170	454	80	338	2e-13	82.0
rs:WP_004689013	DNA topoisomerase I [Brucella suis].	26.44	416	240	15	70	452	253	635	2e-13	82.8
rs:WP_002892042	DNA topoisomerase I [Campylobacter jejuni].	25.12	426	247	17	47	450	225	600	2e-13	82.8
rs:WP_014066714	DNA topoisomerase I [Rhodothermus marinus].	26.36	349	216	11	41	377	254	573	2e-13	82.8
rs:WP_013253491	DNA topoisomerase I [Spirochaeta smaragdinae].	26.79	321	197	8	41	354	254	543	2e-13	82.8
rs:WP_032851656	DNA topoisomerase I [Pasteurella multocida].	24.01	379	239	13	77	446	290	628	2e-13	82.8
tr:F2RAB3_STRVP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.96	293	165	11	77	354	335	593	2e-13	82.8
rs:WP_023478680	DNA topoisomerase I [Enterobacter cloacae].	26.84	380	227	15	77	446	284	622	2e-13	82.8
rs:WP_034370861	DNA topoisomerase I [Dermabacter hominis].	26.23	324	194	9	47	356	267	559	2e-13	82.8
sp:TOP1_PASMU	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.01	379	239	13	77	446	290	628	2e-13	82.8
rs:XP_012287250	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Orussus abietinus].	24.49	441	267	15	39	452	295	696	2e-13	82.8
tr:L7NK28_PHODP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.77	381	225	16	77	446	291	628	2e-13	82.8
rs:WP_019167868	DNA topoisomerase I [Staphylococcus intermedius].	22.46	423	267	15	49	452	226	606	2e-13	82.8
rs:WP_022149077	DNA topoisomerase [Prevotella sp. CAG:1320].	25.68	296	189	8	47	340	222	488	2e-13	82.8
rs:WP_013951507	DNA topoisomerase I [Candidatus Midichloria mitochondrii].	23.42	444	275	14	42	452	226	637	2e-13	82.8
rs:WP_030228518	DNA topoisomerase I [Streptomyces lavendulae].	26.96	293	165	11	77	354	298	556	2e-13	82.8
rs:WP_011679534	DNA topoisomerase I [Leuconostoc mesenteroides].	24.34	415	232	18	66	452	265	625	2e-13	82.8
rs:WP_004164241	DNA topoisomerase I [Leuconostoc mesenteroides].	24.34	415	232	18	66	452	265	625	2e-13	82.8
rs:WP_030323404	DNA topoisomerase I [Streptomyces flavochromogenes].	26.96	293	165	11	77	354	299	557	2e-13	82.8
rs:WP_031295641	DNA topoisomerase I [Leuconostoc mesenteroides].	24.34	415	232	18	66	452	267	627	2e-13	82.8
rs:WP_028741377	DNA topoisomerase I [Rhizobium leguminosarum].	24.83	439	267	15	47	452	230	638	2e-13	82.8
rs:WP_024512407	DNA topoisomerase I [Bradyrhizobium sp. ARR65].	24.89	442	268	13	45	454	228	637	2e-13	82.8
rs:WP_007079454	DNA topoisomerase I [Aeromicrobium marinum].	27.88	312	184	13	54	354	264	545	2e-13	82.8
rs:XP_001265835	DNA topoisomerase III, putative [Neosartorya fischeri NRRL 181].	25.68	331	190	8	45	358	209	500	2e-13	82.4
tr:T1A8I6_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EQD53133.1}; Flags: Fragment;	28.74	247	159	7	45	290	1	231	2e-13	79.3
rs:XP_004574243	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Maylandia zebra].	22.68	441	261	15	40	453	261	648	2e-13	82.8
rs:WP_007525380	DNA topoisomerase I [Desulfovibrio sp. A2].	25.48	416	258	13	53	452	231	610	2e-13	82.8
rs:WP_007264936	DNA topoisomerase I [Streptomyces sp. C].	26.96	293	165	11	77	354	298	556	2e-13	82.8
tr:Q0BU00_GRABC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.89	454	271	16	31	452	232	647	2e-13	82.8
rs:WP_025267939	DNA topoisomerase I [Leuconostoc mesenteroides].	24.34	415	232	18	66	452	265	625	2e-13	82.8
rs:WP_035113522	DNA topoisomerase I [Corynebacterium auriscanis].	24.12	369	232	8	31	377	248	590	2e-13	82.8
rs:WP_026940978	DNA topoisomerase I [Hellea balneolensis].	25.78	419	239	15	71	454	256	637	2e-13	82.8
rs:WP_048342573	DNA topoisomerase I [Cellulomonas sp. A375-1].	26.60	376	229	11	31	387	241	588	2e-13	82.8
rs:WP_001454855	DNA topoisomerase I [Escherichia coli].	25.80	376	236	12	77	446	284	622	2e-13	82.8
rs:WP_047651111	MULTISPECIES: DNA topoisomerase I [Enterobacter].	26.05	380	230	14	77	446	284	622	2e-13	82.8
tr:D0YYM1_PHODD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.77	381	225	16	77	446	261	598	2e-13	82.8
tr:S5VWG9_ENTFC	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AGS75352.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AGS75352.1};	25.75	233	162	3	207	437	8	231	2e-13	80.9
rs:WP_046204013	DNA topoisomerase I [Corynebacterium argentoratense].	23.44	320	207	7	41	351	265	555	2e-13	82.8
rs:WP_036090489	DNA topoisomerase I [Leuconostoc mesenteroides].	24.34	415	232	18	66	452	265	625	2e-13	82.8
rs:WP_006718217	topoisomerase I [Aggregatibacter segnis].	24.40	377	240	13	77	446	290	628	2e-13	82.8
rs:WP_037602065	DNA topoisomerase I [Streptacidiphilus rugosus].	27.04	318	186	12	77	379	309	595	2e-13	82.8
rs:WP_032582168	DNA topoisomerase I [Campylobacter jejuni].	25.35	426	246	17	47	450	225	600	2e-13	82.8
rs:WP_007762029	DNA topoisomerase I [Bacteroides finegoldii].	26.80	291	179	8	47	334	223	482	2e-13	82.8
rs:WP_006312670	MULTISPECIES: DNA topoisomerase I [Agrobacterium].	25.57	442	260	16	47	452	230	638	2e-13	82.8
rs:WP_019605119	topoisomerase I [Teredinibacter turnerae].	25.12	422	266	13	42	452	261	643	2e-13	82.8
rs:WP_005468581	DNA topoisomerase I [Porphyromonas catoniae].	27.69	260	155	6	77	334	251	479	2e-13	82.8
tr:R0LCK4_STREE	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EOB20731.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EOB20731.1};	27.56	254	131	10	211	452	12	224	2e-13	80.5
rs:WP_029076598	DNA topoisomerase I [Kaistia adipata].	25.64	429	246	16	60	452	243	634	2e-13	82.8
rs:WP_036764082	DNA topoisomerase I [Photobacterium damselae].	26.77	381	225	16	77	446	291	628	2e-13	82.8
rs:WP_004072698	DNA topoisomerase I [Desulfobacter postgatei].	23.76	425	271	14	47	452	225	615	2e-13	82.8
rs:WP_041399266	DNA topoisomerase I [Sphaerobacter thermophilus].	24.26	474	262	17	41	449	221	662	2e-13	82.8
rs:WP_038833965	DNA topoisomerase I [Campylobacter coli].	25.29	431	252	17	41	450	219	600	2e-13	82.8
rs:WP_008538386	DNA topoisomerase I [Megamonas funiformis].	25.11	446	255	18	40	457	230	624	2e-13	82.8
tr:F6X812_XENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.35	454	265	19	29	453	240	639	2e-13	82.8
rs:WP_032450637	DNA topoisomerase I [Brucella suis].	26.68	416	239	15	70	452	253	635	2e-13	82.8
rs:WP_016235984	DNA topoisomerase 1 [Escherichia coli].	25.80	376	236	12	77	446	284	622	2e-13	82.8
rs:WP_033857306	hypothetical protein, partial [Acinetobacter baumannii].	43.96	91	50	1	257	347	13	102	2e-13	77.0
rs:WP_000520423	topoisomerase I [Vibrio albensis].	26.25	381	227	15	77	446	292	629	2e-13	82.8
rs:WP_047061015	DNA topoisomerase I [Enterobacter asburiae].	26.05	380	230	14	77	446	284	622	2e-13	82.8
rs:WP_036025557	DNA topoisomerase I [Bradyrhizobium yuanmingense].	24.59	423	256	12	61	452	244	634	2e-13	82.8
rs:WP_022279654	DNA topoisomerase [Dorea formicigenerans CAG:28].	23.61	449	277	16	28	457	69	470	2e-13	82.4
rs:WP_002664440	DNA topoisomerase, partial [Streptococcus pneumoniae].	27.56	254	131	10	211	452	3	215	2e-13	80.1
rs:WP_003547455	DNA topoisomerase I [Rhizobium leguminosarum].	24.83	439	267	15	47	452	230	638	2e-13	82.8
rs:WP_048078736	MULTISPECIES: DNA topoisomerase I [Desulfurococcus].	26.52	313	187	11	74	377	286	564	2e-13	82.4
rs:WP_003713049	hypothetical protein, partial [Lactobacillus oris].	34.25	146	93	2	254	397	4	148	2e-13	79.7
rs:NP_001120391	DNA topoisomerase 3-beta-1 isoform 2 [Xenopus (Silurana) tropicalis].	23.35	454	265	19	29	453	238	637	2e-13	82.8
rs:WP_045782768	DNA topoisomerase I [Klebsiella michiganensis].	26.33	376	234	12	77	446	284	622	2e-13	82.8
rs:WP_016150334	DNA topoisomerase 1 [Citrobacter sp. KTE30].	25.80	376	236	12	77	446	284	622	2e-13	82.8
rs:WP_036015111	DNA topoisomerase I [Bradyrhizobium yuanmingense].	24.59	423	256	12	61	452	244	634	2e-13	82.8
rs:WP_027634208	DNA topoisomerase I [Clostridium hydrogeniformans].	25.12	406	234	14	73	454	249	608	2e-13	82.4
rs:WP_002800263	DNA topoisomerase I [Campylobacter coli].	25.23	432	251	17	41	450	219	600	2e-13	82.4
rs:WP_002671672	DNA topoisomerase I [Treponema denticola].	24.83	435	267	16	36	452	232	624	2e-13	82.8
rs:WP_045262402	DNA topoisomerase I [Microbacterium oxydans].	28.12	320	175	11	51	356	268	546	2e-13	82.8
rs:WP_042308078	DNA topoisomerase I [Citrobacter werkmanii].	26.77	381	226	14	77	446	284	622	2e-13	82.8
rs:WP_004323094	MULTISPECIES: DNA topoisomerase I [Bacteroides].	25.40	315	186	8	36	334	201	482	2e-13	82.8
tr:H4GHS5_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.18	413	232	19	65	452	263	623	2e-13	82.4
rs:WP_043592348	DNA topoisomerase I [Chromobacterium haemolyticum].	22.92	480	264	14	49	459	233	675	2e-13	82.8
rs:WP_005600147	topoisomerase I [Vibrio scophthalmi].	26.95	371	207	12	42	386	242	574	2e-13	82.8
rs:WP_035040032	DNA topoisomerase I [Catonella morbi].	26.35	444	262	17	36	457	213	613	2e-13	82.4
rs:XP_011755460	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha [Macaca nemestrina].	25.85	383	218	13	94	450	345	687	2e-13	82.8
rs:WP_016663290	DNA topoisomerase I [Dermabacter sp. HFH0086].	26.23	324	194	9	47	356	267	559	2e-13	82.8
rs:WP_024289852	DNA topoisomerase I [Microbacterium sp. KROCY2].	28.31	332	194	11	77	389	296	602	2e-13	82.8
tr:A0A0D3L9T6_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.58	301	172	7	47	334	219	483	2e-13	82.8
rs:WP_002864986	DNA topoisomerase I [Campylobacter jejuni].	25.12	426	247	17	47	450	225	600	2e-13	82.4
rs:WP_017575781	DNA topoisomerase I [Nocardiopsis kunsanensis].	25.64	351	219	10	42	379	277	598	2e-13	82.8
rs:WP_032204508	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	2e-13	82.8
rs:WP_044808717	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	2e-13	82.8
rs:WP_027665389	DNA topoisomerase I [Rhizobium leguminosarum].	24.66	438	269	14	47	452	230	638	2e-13	82.8
rs:WP_042964624	DNA topoisomerase I [Campylobacter coli].	25.00	432	252	17	41	450	219	600	2e-13	82.4
rs:WP_002937473	DNA topoisomerase I [Campylobacter jejuni].	25.12	426	247	17	47	450	225	600	2e-13	82.4
rs:WP_002839175	DNA topoisomerase I [Campylobacter coli].	25.23	432	251	17	41	450	219	600	2e-13	82.4
rs:WP_029508697	DNA topoisomerase I [Leuconostoc fallax].	24.88	410	236	19	66	452	229	589	2e-13	82.4
rs:WP_010332637	DNA topoisomerase I subunit omega [Escherichia albertii].	25.80	376	236	12	77	446	284	622	2e-13	82.8
tr:A0A0F4KIT0_9ACTN	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJY46300.1}; Flags: Fragment;	26.62	293	166	11	77	354	298	556	2e-13	82.4
rs:WP_005390799	DNA topoisomerase I [Corynebacterium glucuronolyticum].	24.86	358	228	10	41	386	252	580	2e-13	82.8
rs:WP_032586403	DNA topoisomerase I [Campylobacter jejuni].	25.35	426	246	17	47	450	225	600	2e-13	82.4
rs:WP_015796992	DNA topoisomerase I [Catenulispora acidiphila].	29.87	298	150	15	77	354	304	562	2e-13	82.8
rs:WP_038272057	DNA topoisomerase I [Xylella fastidiosa].	27.23	404	231	17	43	413	229	602	2e-13	82.8
rs:WP_028068227	DNA topoisomerase I [Sphingobacterium thalpophilum].	25.86	263	163	6	77	335	250	484	2e-13	82.8
rs:WP_013836048	DNA topoisomerase I [Thioalkalimicrobium cyclicum].	27.80	295	175	7	43	334	219	478	2e-13	82.8
rs:WP_012895567	DNA topoisomerase I [Streptosporangium roseum].	26.79	336	198	12	37	354	249	554	2e-13	82.8
rs:WP_010494155	DNA topoisomerase I [Lactobacillus acidipiscis].	23.95	430	261	16	43	452	216	599	2e-13	82.4
rs:WP_022661992	DNA topoisomerase I [Desulfovibrio longus].	22.80	421	263	11	47	450	228	603	2e-13	82.8
tr:A0A016UL69_9BILA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EYC15965.1};	25.14	366	226	11	40	398	260	584	2e-13	82.4
rs:WP_030692562	DNA topoisomerase I [Streptomyces globisporus].	26.96	293	165	11	77	354	299	557	2e-13	82.8
rs:WP_042101137	DNA topoisomerase I [Escherichia coli].	26.06	376	235	12	77	446	284	622	2e-13	82.8
rs:XP_011252740	PREDICTED: DNA topoisomerase 3-beta-1 [Camponotus floridanus].	24.45	364	219	13	37	385	258	580	2e-13	82.8
rs:WP_031830983	hypothetical protein [Vibrio parahaemolyticus].	33.82	136	89	1	268	402	9	144	2e-13	77.8
tr:A0A069CW20_9LACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:GAK31587.1};	36.62	142	79	5	226	365	10	142	2e-13	77.8
rs:WP_032342674	DNA topoisomerase I [Escherichia coli].	25.80	376	236	12	77	446	284	622	2e-13	82.8
rs:WP_014162685	DNA topoisomerase I [Thermovirga lienii].	23.64	440	270	15	36	453	232	627	2e-13	82.4
rs:WP_044962176	DNA topoisomerase III, partial [Blautia sp. KLE 1732].	32.17	143	92	4	34	175	221	359	2e-13	81.3
rs:WP_043487167	DNA topoisomerase I [Pseudomonas aeruginosa].	24.63	410	246	13	74	459	260	630	2e-13	82.4
rs:WP_005337825	DNA topoisomerase I [Dorea formicigenerans].	23.61	449	277	16	28	457	213	614	2e-13	82.4
tr:K1U4K1_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC77123.1};	39.34	122	65	2	278	397	6	120	2e-13	77.8
rs:WP_004369289	DNA topoisomerase I [Prevotella oralis].	25.60	336	214	10	4	334	179	483	2e-13	82.4
rs:WP_006213774	DNA topoisomerase I [Kocuria palustris].	28.31	332	194	11	77	389	296	602	2e-13	82.8
rs:WP_030495830	DNA topoisomerase I [Microtetraspora glauca].	26.96	293	165	11	77	354	299	557	2e-13	82.8
rs:WP_044362274	DNA topoisomerase I [Vibrio fluvialis].	26.59	346	190	12	62	385	273	576	2e-13	82.8
rs:WP_002539778	DNA topoisomerase I [Propionibacterium acnes].	25.26	384	227	14	35	388	237	590	2e-13	82.8
rs:WP_019103996	DNA topoisomerase I, partial [Chromobacterium sp. C-61].	22.92	480	264	14	49	459	221	663	3e-13	82.4
tr:X8B6F9_MYCAV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.13	394	235	12	35	399	237	599	3e-13	82.4
tr:U6NV32_HAECO	SubName: Full=Toprim and DNA topoisomerase domain containing protein {ECO:0000313|EMBL:CDJ84401.1}; Flags: Fragment;	24.86	366	214	11	40	388	258	579	3e-13	82.8
rs:WP_015711082	DNA topoisomerase I [Treponema azotonutricium].	24.04	470	260	19	36	449	229	657	3e-13	82.4
rs:WP_035463685	DNA topoisomerase I [Lactobacillus ceti].	23.67	414	255	14	57	452	229	599	3e-13	82.4
rs:WP_035588535	DNA topoisomerase I [Hippea jasoniae].	24.81	399	232	14	77	454	252	603	3e-13	82.4
rs:WP_028719490	DNA topoisomerase I [Paracoccus yeei].	24.37	439	271	14	41	454	223	625	3e-13	82.8
rs:WP_046800293	DNA topoisomerase I [Agrobacterium sp. LC34].	25.51	443	259	16	47	452	230	638	3e-13	82.8
rs:WP_033389985	DNA topoisomerase I, partial [Kibdelosporangium aridum].	26.12	356	214	11	40	377	188	512	3e-13	82.8
rs:WP_019684867	DNA topoisomerase I [Mycobacterium avium].	25.38	394	234	12	35	399	257	619	3e-13	82.8
rs:WP_002779424	DNA topoisomerase I [Campylobacter coli].	25.00	432	252	17	41	450	219	600	3e-13	82.4
rs:WP_002874307	DNA topoisomerase I [Campylobacter jejuni].	25.35	434	251	18	47	458	225	607	3e-13	82.4
rs:WP_018416638	topoisomerase I [Teredinibacter turnerae].	25.12	422	266	13	42	452	261	643	3e-13	82.8
tr:J9FBN9_WUCBA	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EJW86992.1};	24.79	359	223	11	40	388	279	600	3e-13	82.4
rs:WP_043670276	DNA topoisomerase I [Clavibacter michiganensis].	27.42	372	216	16	30	379	239	578	3e-13	82.8
rs:WP_043455798	DNA topoisomerase I, partial [Granulibacter bethesdensis].	24.89	454	271	16	31	452	221	636	3e-13	82.8
rs:WP_043452743	DNA topoisomerase I [Granulibacter bethesdensis].	24.89	454	271	16	31	452	221	636	3e-13	82.8
rs:NP_001182501	DNA topoisomerase 3-beta-1 isoform 1 [Xenopus (Silurana) tropicalis].	23.35	454	265	19	29	453	251	650	3e-13	82.8
rs:WP_020330226	MULTISPECIES: DNA topoisomerase I [Vibrio].	26.59	346	190	12	62	385	273	576	3e-13	82.8
rs:WP_001516492	MULTISPECIES: topoisomerase I [Escherichia].	25.53	376	237	12	77	446	284	622	3e-13	82.8
rs:WP_036100200	DNA topoisomerase I [Leptotrichia sp. oral taxon 215].	24.01	354	220	8	40	379	214	532	3e-13	82.4
rs:WP_006249032	topoisomerase I [Mannheimia haemolytica].	26.65	379	229	15	77	446	290	628	3e-13	82.8
rs:WP_043808620	DNA topoisomerase I [Rhodococcus triatomae].	26.36	330	195	10	41	354	269	566	3e-13	82.8
rs:WP_034471440	DNA topoisomerase I [Afipia sp. P52-10].	25.23	428	254	14	60	454	243	637	3e-13	82.8
rs:WP_045568957	DNA topoisomerase I [Vibrio sp. S234-5].	27.30	326	180	10	77	386	290	574	3e-13	82.8
rs:WP_042908466	DNA topoisomerase I [Mycobacterium avium].	25.38	394	234	12	35	399	257	619	3e-13	82.8
rs:WP_023862894	DNA topoisomerase I [Mycobacterium avium].	25.38	394	234	12	35	399	257	619	3e-13	82.8
rs:WP_008743043	DNA topoisomerase I [Streptomyces sp. Mg1].	26.62	293	166	11	77	354	298	556	3e-13	82.8
rs:WP_024467401	DNA topoisomerase I [Treponema pedis].	25.24	420	256	13	50	452	253	631	3e-13	82.4
rs:WP_022496432	DNA topoisomerase [Streptococcus salivarius CAG:79].	24.81	399	229	14	75	452	1	349	3e-13	81.6
rs:XP_009691223	DNA topoisomerase III [Theileria orientalis strain Shintoku].	22.89	402	260	13	3	393	223	585	3e-13	82.4
rs:WP_022227777	DNA topoisomerase [Megamonas funiformis CAG:377].	25.11	446	255	18	40	457	230	624	3e-13	82.4
rs:WP_020428718	DNA topoisomerase I [Vibrio fluvialis].	26.59	346	190	12	62	385	273	576	3e-13	82.4
rs:WP_011949980	DNA topoisomerase I [Brucella ovis].	27.16	416	237	15	70	452	253	635	3e-13	82.4
tr:V2XKU8_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.35	444	262	17	36	457	215	615	3e-13	82.4
rs:WP_009834706	topoisomerase I [Marinomonas sp. MED121].	24.19	401	233	15	68	446	279	630	3e-13	82.4
rs:WP_023524932	DNA topoisomerase I [Leptospirillum sp. Group II 'C75'].	26.91	431	256	19	41	458	210	594	3e-13	82.4
rs:WP_001695925	DNA topoisomerase I [Escherichia coli].	25.80	376	236	12	77	446	284	622	3e-13	82.4
rs:WP_031643886	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	25.33	383	221	13	102	459	1	343	3e-13	80.9
rs:XP_012346287	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Apis florea].	24.29	354	226	11	40	385	126	445	3e-13	82.4
rs:WP_004302491	DNA topoisomerase I [Bacteroides ovatus].	25.40	315	186	8	36	334	201	482	3e-13	82.4
rs:WP_034825430	DNA topoisomerase I [Hyphomonas sp. T16B2].	24.60	435	263	14	47	452	231	629	3e-13	82.4
tr:B3C7S7_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.91	301	183	7	40	334	226	492	3e-13	82.4
tr:A0A0B2VSG7_TOXCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.63	364	228	10	37	390	318	641	3e-13	82.4
rs:WP_047131249	DNA topoisomerase I [Staphylococcus condimenti].	24.43	397	235	15	77	452	254	606	3e-13	82.4
tr:D6KHW4_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.07	428	260	16	47	454	251	633	3e-13	82.4
rs:WP_034004417	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	25.71	319	183	11	166	459	9	298	3e-13	80.1
rs:WP_045360425	DNA topoisomerase I [Enterobacter aerogenes].	25.66	378	234	14	77	446	284	622	3e-13	82.4
rs:WP_039263555	MULTISPECIES: DNA topoisomerase I [Enterobacter].	26.05	380	230	14	77	446	284	622	3e-13	82.4
rs:WP_043644116	DNA topoisomerase I [Nocardioides alkalitolerans].	27.71	332	194	13	37	354	250	549	3e-13	82.4
rs:WP_020577087	hypothetical protein [Actinopolymorpha alba].	26.52	362	218	14	42	387	267	596	3e-13	82.4
rs:WP_018966557	hypothetical protein, partial [Prevotella loescheii].	32.45	188	118	4	239	425	4	183	3e-13	79.7
rs:XP_012170324	PREDICTED: DNA topoisomerase 3-beta-1 [Bombus terrestris].	24.42	385	245	13	12	385	231	580	3e-13	82.4
rs:XP_001391772	DNA topoisomerase 3 [Aspergillus niger CBS 513.88].	25.94	347	197	10	44	369	266	573	3e-13	82.4
rs:WP_006251055	topoisomerase I [Mannheimia haemolytica].	26.65	379	229	15	77	446	290	628	3e-13	82.4
rs:XP_009619602	PREDICTED: DNA topoisomerase 3-beta isoform X3 [Nicotiana tomentosiformis].	24.32	370	231	13	39	393	195	530	3e-13	82.4
rs:XP_002617565	hypothetical protein CLUG_03009 [Clavispora lusitaniae ATCC 42720].	23.82	382	250	9	37	406	259	611	3e-13	82.4
rs:WP_010696774	DNA topoisomerase I [Treponema denticola].	24.02	433	273	15	36	452	232	624	3e-13	82.4
rs:WP_044154826	DNA topoisomerase I [Bacteroides intestinalis].	25.91	301	183	7	40	334	216	482	3e-13	82.4
rs:WP_046723921	DNA topoisomerase I [Streptomyces xiamenensis].	24.77	327	203	10	40	354	264	559	3e-13	82.8
tr:N8LPK6_BRUOV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.16	416	237	15	70	452	262	644	3e-13	82.4
rs:WP_031128143	DNA topoisomerase I [Streptomyces sp. NRRL WC-3719].	26.96	293	165	11	77	354	299	557	3e-13	82.4
rs:WP_045697622	DNA topoisomerase I [Hyphomonas sp. BRH_c22].	24.36	431	269	12	47	452	231	629	3e-13	82.4
rs:WP_034455431	DNA topoisomerase I [Buttiauxella agrestis].	25.27	376	238	12	77	446	284	622	3e-13	82.4
rs:WP_027146697	DNA topoisomerase I [Mesorhizobium sp. WSM3626].	25.17	449	262	17	41	452	224	635	3e-13	82.4
rs:WP_038813768	DNA topoisomerase I [Campylobacter jejuni].	25.35	426	246	17	47	450	225	600	3e-13	82.4
rs:WP_005636823	MULTISPECIES: DNA topoisomerase III [Bacteroidales].	25.00	380	240	12	18	385	216	562	3e-13	82.0
rs:WP_047463544	DNA topoisomerase I [Citrobacter koseri].	25.53	380	232	14	77	446	284	622	3e-13	82.4
rs:WP_036549903	DNA topoisomerase I [Nitrincola lacisaponensis].	24.67	377	237	13	77	446	296	632	3e-13	82.4
rs:WP_045866076	DNA topoisomerase I [Streptomyces sp. WMMB 714].	25.00	328	197	11	42	354	264	557	3e-13	82.4
rs:XP_688695	PREDICTED: DNA topoisomerase 3-alpha [Danio rerio].	23.60	445	272	15	40	455	287	692	3e-13	82.4
rs:WP_023810547	DNA topoisomerase I [Mesorhizobium sp. L2C084A000].	24.72	449	264	17	41	452	224	635	3e-13	82.4
rs:WP_047370484	DNA topoisomerase I [Kluyvera intermedia].	25.91	386	223	14	77	446	284	622	3e-13	82.4
rs:XP_012346286	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Apis florea].	24.29	354	226	11	40	385	261	580	3e-13	82.4
rs:WP_017650630	DNA topoisomerase [Streptococcus agalactiae].	26.65	334	203	9	74	399	278	577	3e-13	82.0
rs:WP_014666685	DNA topoisomerase I [Helicobacter cinaedi].	24.48	433	265	15	41	454	224	613	3e-13	82.4
rs:XP_007376371	DNA topoisomerase [Spathaspora passalidarum NRRL Y-27907].	23.28	408	264	11	18	408	231	606	3e-13	82.0
sp:TOP1_VIBCH	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	26.25	381	227	15	77	446	292	629	3e-13	82.4
rs:WP_001487192	DNA topoisomerase I [Escherichia coli].	25.80	376	236	12	77	446	284	622	3e-13	82.4
tr:A0A016UM26_9BILA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EYC15966.1};	25.14	366	226	11	40	398	280	604	3e-13	82.4
rs:WP_015486301	DNA topoisomerase I [Thalassolituus oleivorans].	25.80	438	265	17	32	452	248	642	3e-13	82.4
rs:WP_003022384	DNA topoisomerase I [Blautia hansenii].	24.48	429	264	13	48	457	227	614	3e-13	82.4
gp:CP004054_4499	DNA topoisomerase III [Pseudomonas aeruginosa PA1]	24.63	410	246	13	74	459	212	582	3e-13	82.0
rs:WP_033145741	DNA topoisomerase I [Enterobacter cloacae].	26.05	380	230	14	77	446	284	622	3e-13	82.4
rs:WP_046121520	DNA topoisomerase I [Vibrio cholerae].	26.25	381	227	15	77	446	292	629	3e-13	82.4
rs:WP_037775864	DNA topoisomerase I [Streptomyces sp. HPH0547].	25.51	341	197	12	37	354	260	566	3e-13	82.4
tr:L1MJJ4_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.97	261	156	7	77	335	263	493	3e-13	82.4
tr:U2RB34_9FUSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.01	354	220	8	40	379	217	535	3e-13	82.4
rs:WP_005605437	DNA topoisomerase I [Granulicatella adiacens].	23.53	442	275	12	28	452	212	607	3e-13	82.4
rs:XP_007513181	DNA topoisomerase I [Bathycoccus prasinos].	25.05	471	242	19	65	458	389	825	3e-13	82.8
rs:WP_042251448	DNA topoisomerase I [Paracoccus sp. PAMC 22219].	24.72	441	232	16	77	454	259	662	3e-13	82.4
rs:XP_010546323	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Tarenaya hassleriana].	24.53	477	270	20	18	451	243	672	3e-13	82.4
rs:WP_022072476	DNA topoisomerase [Clostridium bartlettii CAG:1329].	23.53	408	245	13	68	454	247	608	3e-13	82.4
rs:WP_011441309	DNA topoisomerase I [Rhodopseudomonas palustris].	25.35	426	256	14	60	454	243	637	3e-13	82.4
rs:WP_041413613	DNA topoisomerase I [Shewanella frigidimarina].	24.93	361	223	10	42	388	257	583	3e-13	82.4
rs:WP_000520429	topoisomerase I [Vibrio cholerae].	26.25	381	227	15	77	446	292	629	3e-13	82.4
rs:WP_029731298	DNA topoisomerase I [Dorea sp. AGR2135].	23.61	449	277	16	28	457	213	614	3e-13	82.4
rs:WP_040800812	DNA topoisomerase I [marine actinobacterium PHSC20C1].	26.80	347	198	14	30	356	247	557	3e-13	82.4
rs:WP_005828774	MULTISPECIES: DNA topoisomerase III [Bacteroides].	25.68	331	210	9	61	385	262	562	3e-13	82.0
rs:WP_002956759	DNA topoisomerase I [Helicobacter cinaedi].	24.48	433	265	15	41	454	224	613	3e-13	82.4
tr:D1C7I9_SPHTD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.26	474	262	17	41	449	282	723	3e-13	82.4
rs:WP_000520424	topoisomerase I [Vibrio cholerae].	26.25	381	227	15	77	446	292	629	3e-13	82.4
rs:WP_021967574	DNA topoisomerase [Bacteroides intestinalis CAG:564].	25.91	301	183	7	40	334	216	482	3e-13	82.4
tr:A0A0A2VZ73_BEABA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.33	376	234	12	77	446	284	622	3e-13	82.4
rs:WP_023655168	DNA topoisomerase I [Erwinia piriflorinigrans].	27.06	388	233	16	77	452	259	608	3e-13	82.4
rs:WP_007347925	DNA topoisomerase I [Bartonella rattimassiliensis].	26.22	431	252	18	55	452	239	636	3e-13	82.4
rs:WP_035944809	DNA topoisomerase I [Frankia sp. Iso899].	26.89	331	195	11	42	354	251	552	3e-13	82.4
rs:WP_000520432	topoisomerase I [Vibrio cholerae].	26.25	381	227	15	77	446	292	629	3e-13	82.4
rs:WP_044532637	DNA topoisomerase I, partial [Bacteroides intestinalis].	25.91	301	183	7	40	334	216	482	3e-13	82.0
rs:XP_009619600	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Nicotiana tomentosiformis].	24.12	369	233	12	39	393	213	548	3e-13	82.4
rs:WP_002627127	DNA topoisomerase I [Cystobacter fuscus].	24.33	448	268	14	41	452	300	712	3e-13	82.4
rs:WP_035913299	DNA topoisomerase I [Lechevalieria aerocolonigenes].	26.06	353	216	11	41	377	249	572	3e-13	82.4
rs:WP_003136185	DNA topoisomerase I [Lactococcus garvieae].	23.02	443	266	15	34	452	239	630	3e-13	82.4
rs:WP_000520430	topoisomerase I [Vibrio cholerae].	26.25	381	227	15	77	446	292	629	3e-13	82.4
rs:XP_009619599	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Nicotiana tomentosiformis].	24.12	369	233	12	39	393	254	589	3e-13	82.4
rs:XP_008477884	PREDICTED: DNA topoisomerase 3-alpha-like [Diaphorina citri].	23.73	434	268	14	41	450	34	428	3e-13	82.0
rs:WP_003609775	DNA topoisomerase I [Methylosinus trichosporium].	25.69	432	242	16	60	452	243	634	3e-13	82.4
rs:WP_025394120	DNA topoisomerase I [Rhizobium leguminosarum].	24.83	439	267	15	47	452	230	638	3e-13	82.4
rs:WP_020804553	DNA topoisomerase I, partial [Klebsiella pneumoniae].	26.84	380	227	15	77	446	284	622	3e-13	82.0
rs:WP_030866109	DNA topoisomerase I [Streptomyces sp. NRRL F-2747].	26.62	293	166	11	77	354	298	556	3e-13	82.4
rs:WP_008154288	DNA topoisomerase I [Parabacteroides johnsonii].	26.02	369	235	11	40	384	213	567	3e-13	82.4
rs:WP_001335024	topoisomerase I [Escherichia coli].	25.80	376	236	12	77	446	284	622	3e-13	82.4
rs:WP_035544208	hypothetical protein, partial [Holospora elegans].	23.84	432	273	12	43	449	228	628	3e-13	82.4
rs:WP_005845602	DNA topoisomerase I [Prevotella dentalis].	24.64	349	224	12	77	401	252	585	3e-13	82.4
rs:WP_038125361	DNA topoisomerase I [Veillonella sp. 3_1_44].	24.07	428	260	16	47	454	295	677	3e-13	82.4
tr:I2G1E9_USTH4	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.81	310	179	9	59	357	293	562	3e-13	82.4
tr:F1R242_DANRE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.20	444	275	15	40	455	287	692	3e-13	82.4
rs:WP_035575028	hypothetical protein, partial [Holospora undulata].	23.84	432	273	12	43	449	228	628	3e-13	82.4
rs:WP_044063101	DNA topoisomerase I [Prevotella sp. oral taxon 473].	27.97	261	156	7	77	335	252	482	3e-13	82.4
sp:TOP1_RICTY	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	23.68	418	246	15	65	449	250	627	3e-13	82.4
rs:WP_045335024	DNA topoisomerase I [Enterobacter cloacae].	26.05	380	230	14	77	446	284	622	3e-13	82.4
rs:WP_009112799	topoisomerase I [Brenneria sp. EniD312].	26.38	398	230	17	68	446	269	622	3e-13	82.4
tr:A0A0E0NQ39_ORYRU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.35	423	262	14	39	435	270	660	3e-13	82.4
rs:WP_047465058	DNA topoisomerase I [Agrobacterium rhizogenes].	24.77	440	267	13	47	452	230	639	3e-13	82.4
rs:WP_039076930	DNA topoisomerase I [Enterobacter sp. Bisph2].	27.08	325	181	11	77	385	284	568	3e-13	82.4
rs:WP_008616602	DNA topoisomerase I subunit omega [Magnetospirillum sp. SO-1].	26.39	432	242	16	60	454	243	635	3e-13	82.4
tr:W1F1E9_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.82	284	166	10	77	356	284	532	3e-13	82.0
rs:WP_040233192	DNA topoisomerase I [Citrobacter sp. CIP 55.13].	25.80	376	236	12	77	446	284	622	3e-13	82.4
rs:WP_020975460	DNA topoisomerase I [Corynebacterium argentoratense].	23.73	316	211	7	41	351	265	555	3e-13	82.4
rs:WP_024164310	DNA topoisomerase I [Rhizobium sp. CF080].	25.36	418	253	15	67	452	248	638	3e-13	82.4
tr:S3ANX1_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.51	341	197	12	37	354	246	552	3e-13	82.4
tr:H2Z238_CIOSA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.73	377	223	13	39	400	299	633	3e-13	82.0
rs:WP_029167774	DNA topoisomerase I [alpha proteobacterium SCGC AAA028-C07].	24.37	439	267	13	50	454	233	640	3e-13	82.4
rs:WP_037625417	DNA topoisomerase I [Streptomyces aureus].	25.70	323	201	9	42	354	264	557	3e-13	82.4
rs:WP_027952528	DNA topoisomerase I [Hallella seregens].	24.64	349	224	12	77	401	252	585	3e-13	82.4
tr:A0A0C7LW27_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.84	314	205	11	49	357	252	539	3e-13	82.0
rs:WP_048436992	DNA topoisomerase I [Methylobacterium platani].	26.39	451	239	17	43	452	236	634	3e-13	82.4
tr:A8AG75_CITK8	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.53	380	232	14	77	446	284	622	3e-13	82.4
rs:WP_034897251	DNA topoisomerase I [Erwinia typographi].	25.32	391	236	15	77	452	284	633	3e-13	82.4
rs:WP_045842316	DNA topoisomerase I [Mycobacterium lepromatosis].	26.32	380	228	12	41	399	274	622	3e-13	82.4
rs:WP_028744828	DNA topoisomerase I [Rhizobium mesoamericanum].	25.28	439	265	15	47	452	230	638	3e-13	82.4
rs:WP_010180521	topoisomerase I [Glaciecola sp. HTCC2999].	26.09	437	260	16	36	452	254	647	3e-13	82.4
rs:WP_001897682	topoisomerase I [Vibrio cholerae].	26.25	381	227	15	77	446	292	629	3e-13	82.4
rs:WP_002529660	DNA topoisomerase I [Propionibacterium acnes].	25.26	384	227	14	35	388	237	590	3e-13	82.4
rs:WP_014229012	MULTISPECIES: topoisomerase I [Klebsiella].	26.25	381	228	15	77	446	284	622	3e-13	82.4
rs:WP_030735352	DNA topoisomerase I [Streptomyces sp. NRRL F-2890].	24.77	327	203	10	40	354	264	559	3e-13	82.4
rs:WP_008781114	DNA topoisomerase III [Bacteroides sp. 3_1_19].	25.98	331	209	9	61	385	262	562	3e-13	82.0
tr:U2DIJ0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.17	143	92	4	34	175	228	366	3e-13	81.3
rs:WP_038066759	DNA topoisomerase I [Thermus filiformis].	23.97	438	265	12	36	454	238	626	3e-13	82.4
rs:WP_002708740	DNA topoisomerase I [Thiothrix nivea].	26.57	399	231	15	31	404	221	582	3e-13	82.4
rs:WP_021023936	topoisomerase I [Salinivibrio costicola].	26.56	384	222	16	77	446	290	627	3e-13	82.4
tr:Q080J2_SHEFN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.93	361	223	10	42	388	273	599	3e-13	82.4
rs:WP_015030876	DNA topoisomerase I [Emticicia oligotrophica].	26.01	296	179	7	45	335	220	480	3e-13	82.4
rs:WP_032749439	DNA topoisomerase I [Klebsiella oxytoca].	25.66	378	234	14	77	446	284	622	3e-13	82.4
rs:WP_040430347	DNA topoisomerase I [Corynebacterium nuruki].	26.77	325	201	11	41	354	257	555	3e-13	82.4
rs:WP_013509246	topoisomerase I [Pantoea sp. At-9b].	26.79	392	229	17	77	452	285	634	3e-13	82.4
tr:A0A0F4ESJ8_9MYCO	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJX75809.1};	26.32	380	228	12	41	399	272	620	3e-13	82.4
rs:WP_040080846	DNA topoisomerase I [Mannheimia haemolytica].	26.65	379	229	15	77	446	290	628	3e-13	82.4
rs:WP_041767061	DNA topoisomerase I [Leifsonia xyli].	27.42	372	220	13	30	380	238	580	3e-13	82.4
tr:E6YR65_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.63	427	230	19	67	452	248	636	3e-13	82.4
rs:WP_042944939	DNA topoisomerase I [Klebsiella oxytoca].	26.25	381	228	15	77	446	284	622	3e-13	82.4
rs:WP_032642185	DNA topoisomerase I [Enterobacter sp. EGD-HP1].	26.05	380	230	14	77	446	284	622	3e-13	82.4
tr:A0A0C7C669_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.61	460	287	16	18	453	194	608	3e-13	82.4
rs:WP_044362462	DNA topoisomerase I [Streptomyces natalensis].	27.30	293	164	10	77	354	301	559	3e-13	82.4
rs:WP_028416080	DNA topoisomerase I [Streptomyces sp. SolWspMP-sol2th].	27.24	290	168	10	77	354	301	559	3e-13	82.4
rs:WP_029262798	MULTISPECIES: DNA topoisomerase I [Microbacterium].	28.12	320	175	11	51	356	268	546	3e-13	82.4
rs:WP_009756043	DNA topoisomerase I [Nitratireductor indicus].	25.51	439	262	16	47	452	230	636	3e-13	82.4
rs:WP_042037482	DNA topoisomerase I [Aeromonas popoffii].	26.30	422	249	15	49	452	259	636	3e-13	82.4
rs:WP_002785538	DNA topoisomerase I [Campylobacter coli].	25.23	432	251	17	41	450	219	600	3e-13	82.0
rs:WP_001961705	DNA topoisomerase I [Vibrio cholerae].	26.25	381	227	15	77	446	292	629	3e-13	82.4
rs:WP_018999216	DNA topoisomerase I [Megamonas rupellensis].	25.11	446	255	18	40	457	230	624	3e-13	82.0
rs:WP_014838214	topoisomerase I [Klebsiella oxytoca].	26.25	381	228	15	77	446	284	622	3e-13	82.4
rs:WP_021791689	hypothetical protein [Thermoplasmatales archaeon I-plasma].	24.94	393	244	13	47	428	243	595	3e-13	82.0
rs:WP_047489312	DNA topoisomerase [Terriglobus sp. TAA 43].	24.37	435	260	16	41	446	232	626	3e-13	82.4
rs:WP_013805099	DNA topoisomerase I [Amycolicicoccus subflavus].	26.52	328	199	12	40	354	271	569	3e-13	82.4
rs:WP_017829062	DNA topoisomerase I [Microbacterium sp. UCD-TDU].	28.22	326	179	11	45	356	262	546	3e-13	82.4
rs:WP_006126427	MULTISPECIES: DNA topoisomerase I [Streptomyces].	27.24	290	168	10	77	354	301	559	3e-13	82.4
rs:WP_019903957	DNA topoisomerase I [Methylobacterium sp. 77].	26.34	429	246	14	57	452	243	634	3e-13	82.4
rs:WP_039708255	DNA topoisomerase I, partial [marine actinobacterium MedAcidi-G1].	25.47	369	221	11	41	385	254	592	3e-13	82.0
rs:WP_016459086	DNA topoisomerase I [Corynebacterium pyruviciproducens].	24.59	370	233	10	35	386	239	580	3e-13	82.4
rs:WP_037265031	DNA topoisomerase I [Rhodococcus rhodnii].	26.12	356	214	11	40	377	268	592	3e-13	82.4
rs:WP_040467782	DNA topoisomerase I [Lactobacillus gastricus].	24.70	413	234	18	65	452	273	633	3e-13	82.0
tr:J9H0M7_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EJX09208.1};	24.44	315	189	8	36	334	211	492	3e-13	82.0
rs:WP_008776858	DNA topoisomerase I [Bacteroides sp. 2_2_4].	25.40	315	186	8	36	334	201	482	3e-13	82.0
rs:WP_019138070	DNA topoisomerase I [Peptoniphilus timonensis].	22.82	425	265	14	47	452	228	608	3e-13	82.0
rs:WP_006062743	DNA topoisomerase I [Corynebacterium durum].	26.20	332	207	11	31	351	247	551	3e-13	82.4
rs:WP_021971636	DNA topoisomerase [Bacteroides sp. CAG:1076].	27.38	263	153	7	77	334	249	478	3e-13	82.0
rs:WP_021064912	hypothetical protein [Agrococcus pavilionensis].	25.22	345	212	9	25	354	230	543	3e-13	82.4
rs:WP_006363417	DNA topoisomerase I [Gemella sanguinis].	24.25	433	248	16	47	452	225	604	3e-13	82.0
rs:WP_046456236	DNA topoisomerase I [Leucobacter sp. Ag1].	28.48	330	188	13	77	387	295	595	3e-13	82.4
rs:WP_024212414	MULTISPECIES: DNA topoisomerase I [Escherichia].	25.53	376	237	12	77	446	284	622	3e-13	82.4
rs:WP_023780594	DNA topoisomerase I [Mesorhizobium sp. LNHC221B00].	25.00	448	264	18	41	452	224	635	3e-13	82.4
rs:WP_037785772	DNA topoisomerase I [Streptomyces sp. CNT318].	25.37	335	194	12	35	354	281	574	3e-13	82.4
rs:WP_020442068	DNA topoisomerase I subunit omega [Corynebacterium terpenotabidum].	28.52	298	175	12	66	351	293	564	3e-13	82.4
rs:WP_029740526	DNA topoisomerase I [Enterobacter asburiae].	26.05	380	230	14	77	446	284	622	3e-13	82.0
rs:WP_048316842	DNA topoisomerase I [Parabacteroides goldsteinii].	25.68	331	210	9	61	385	262	562	3e-13	82.0
tr:A0A0F6AUS4_BRUA1	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:ACD74089.1};	26.08	418	239	15	70	452	204	586	3e-13	82.0
tr:A7LW71_BACO1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.40	315	186	8	36	334	211	492	3e-13	82.0
rs:WP_001886798	topoisomerase I [Vibrio cholerae].	26.08	395	232	16	69	446	278	629	3e-13	82.0
rs:WP_005523284	DNA topoisomerase I [Vibrio mimicus].	25.82	395	233	15	69	446	278	629	3e-13	82.0
rs:WP_024563609	DNA topoisomerase I [Wheat blue dwarf phytoplasma].	23.57	420	257	15	47	450	217	588	3e-13	82.0
rs:WP_028638708	DNA topoisomerase I [Nocardioides sp. URHA0032].	28.08	292	166	11	77	356	290	549	3e-13	82.4
rs:WP_044015757	DNA topoisomerase I [Treponema sp. OMZ 838].	23.64	423	261	13	49	452	223	602	3e-13	82.0
rs:WP_045776269	DNA topoisomerase I [Elstera litoralis].	26.23	427	233	18	65	452	249	632	3e-13	82.4
rs:WP_047239445	DNA topoisomerase I [Corynebacterium epidermidicanis].	25.23	329	205	8	47	362	270	570	3e-13	82.4
rs:WP_031058622	DNA topoisomerase I [Streptomyces ochraceiscleroticus].	25.88	340	196	12	37	354	254	559	3e-13	82.4
rs:WP_044172924	DNA topoisomerase I, partial [Oscillatoria sp. PCC 10802].	25.00	388	235	12	40	417	238	579	3e-13	81.6
gp:CP006730_602	DNA topoisomerase I [Dehalococcoides mccartyi GY50]	21.60	449	257	12	65	450	245	661	3e-13	82.0
tr:F3KGB5_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.50	298	181	8	166	452	64	328	3e-13	81.6
rs:WP_028438482	DNA topoisomerase I [Streptomyces sp. TAA486].	23.50	400	253	13	42	423	269	633	3e-13	82.4
rs:WP_029508370	DNA topoisomerase I [Lactobacillus suebicus].	23.98	417	252	15	55	452	252	622	3e-13	82.0
rs:WP_009632516	DNA topoisomerase I [Synechocystis sp. PCC 7509].	25.22	337	214	8	41	370	249	554	4e-13	82.0
tr:A6VX57_MARMS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.93	361	223	11	36	384	253	577	4e-13	82.0
rs:WP_029149405	DNA topoisomerase I [Microbacterium indicum].	27.40	354	205	12	47	384	269	586	4e-13	82.4
rs:WP_044126648	DNA topoisomerase I [Vibrio cholerae].	26.25	381	227	15	77	446	292	629	4e-13	82.0
rs:XP_006457247	hypothetical protein AGABI2DRAFT_154568 [Agaricus bisporus var. bisporus H97].	25.52	384	235	11	37	405	254	601	4e-13	82.0
tr:A0A0C7C736_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.61	460	287	16	18	453	74	488	4e-13	82.0
rs:WP_031032136	MULTISPECIES: DNA topoisomerase I [Streptomyces].	25.51	341	197	12	37	354	260	566	4e-13	82.4
rs:WP_023335949	DNA topoisomerase 1 [Enterobacter sp. MGH 24].	26.05	380	230	14	77	446	284	622	4e-13	82.0
rs:WP_047647563	DNA topoisomerase I [Enterobacter asburiae].	26.05	380	230	14	77	446	284	622	4e-13	82.0
rs:WP_013895222	DNA topoisomerase I [Mesorhizobium opportunistum].	25.22	448	263	18	41	452	224	635	4e-13	82.0
rs:WP_047791117	DNA topoisomerase I [Spiroplasma eriocheiris].	25.00	404	239	11	65	450	237	594	4e-13	82.0
rs:XP_010103452	DNA topoisomerase 3-alpha [Morus notabilis].	25.08	307	181	6	166	452	368	645	4e-13	82.4
rs:WP_002894594	DNA topoisomerase I [Campylobacter jejuni].	25.12	426	247	17	47	450	225	600	4e-13	82.0
rs:WP_032852404	DNA topoisomerase I [Bacteroides sp. 3_1_23].	25.40	315	186	8	36	334	201	482	4e-13	82.0
tr:W1HHS0_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	26.84	380	227	15	77	446	80	418	4e-13	82.0
rs:WP_010524349	DNA topoisomerase I [Nesterenkonia sp. F].	28.27	336	198	12	37	356	254	562	4e-13	82.4
rs:WP_004179471	topoisomerase I [Klebsiella pneumoniae].	26.84	380	227	15	77	446	284	622	4e-13	82.0
rs:WP_023735323	DNA topoisomerase I [Mesorhizobium sp. LNJC399B00].	25.34	446	257	18	45	452	228	635	4e-13	82.0
rs:WP_018489446	DNA topoisomerase I [Streptomyces sp. CcalMP-8W].	27.24	290	168	10	77	354	301	559	4e-13	82.4
tr:D7JXC8_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.40	315	186	8	36	334	211	492	4e-13	82.0
rs:WP_043801410	DNA topoisomerase I [Arenimonas malthae].	27.74	310	168	12	66	354	254	528	4e-13	82.0
rs:WP_011265411	DNA topoisomerase I [Brucella abortus].	26.08	418	239	15	70	452	253	635	4e-13	82.0
rs:WP_025209884	DNA topoisomerase I [Hippea sp. KM1].	24.44	405	226	15	77	454	255	606	4e-13	82.0
tr:A4AKC9_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.80	347	198	14	30	356	239	549	4e-13	82.0
rs:WP_000520428	topoisomerase I [Vibrio cholerae].	26.25	381	227	15	77	446	292	629	4e-13	82.0
rs:XP_001963417	GF20299 [Drosophila ananassae].	25.00	376	227	16	37	394	256	594	4e-13	82.0
rs:WP_030407664	DNA topoisomerase I [Streptomyces sp. NRRL F-5917].	25.51	341	197	12	37	354	260	566	4e-13	82.0
rs:WP_046084579	DNA topoisomerase I [Streptomyces yogyakartensis].	25.00	328	197	11	42	354	266	559	4e-13	82.0
tr:X1DF39_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_C00312 {ECO:0000313|EMBL:GAH19441.1}; Flags: Fragment;	26.20	271	166	7	56	325	258	495	4e-13	81.6
rs:WP_023825648	DNA topoisomerase I [Mesorhizobium sp. L103C131B0].	25.34	446	257	18	45	452	228	635	4e-13	82.0
rs:WP_025673753	DNA topoisomerase I [Salinivibrio socompensis].	26.30	384	223	16	77	446	290	627	4e-13	82.0
rs:WP_035453817	DNA topoisomerase I [Bartonella bacilliformis].	25.65	421	246	16	67	452	248	636	4e-13	82.0
rs:WP_027506713	DNA topoisomerase I [Rhodococcus sp. UNC23MFCrub1.1].	27.63	333	200	10	35	354	260	564	4e-13	82.0
rs:WP_032435399	DNA topoisomerase I [Klebsiella pneumoniae].	26.84	380	227	15	77	446	284	622	4e-13	82.0
rs:WP_041847165	DNA topoisomerase I [Bartonella bacilliformis].	25.65	421	246	16	67	452	248	636	4e-13	82.0
rs:WP_020195007	topoisomerase I [Vibrio owensii].	25.65	386	223	13	77	446	291	628	4e-13	82.0
rs:WP_000520435	topoisomerase I [Vibrio cholerae].	26.25	381	227	15	77	446	292	629	4e-13	82.0
rs:WP_003856806	MULTISPECIES: topoisomerase I [Enterobacter cloacae complex].	26.05	380	230	14	77	446	284	622	4e-13	82.0
rs:WP_036825650	DNA topoisomerase I [Porphyromonadaceae bacterium COT-184 OH4590].	25.84	267	160	7	77	337	247	481	4e-13	82.0
rs:WP_000520433	topoisomerase I [Vibrio cholerae].	26.25	381	227	15	77	446	292	629	4e-13	82.0
rs:WP_014061723	DNA topoisomerase I [Streptomyces violaceusniger].	25.00	328	197	11	42	354	266	559	4e-13	82.0
tr:U1CM27_ENTGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	26.84	380	227	15	77	446	158	496	4e-13	82.0
rs:WP_009628079	DNA topoisomerase I [Pseudanabaena biceps].	26.18	359	220	10	41	387	249	574	4e-13	82.0
tr:U5VSI3_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.79	377	218	16	47	399	268	610	4e-13	82.0
rs:WP_022187731	DNA topoisomerase [Azospirillum sp. CAG:260].	26.94	438	252	17	47	454	228	627	4e-13	82.0
rs:WP_002968861	DNA topoisomerase I [Brucella abortus].	26.08	418	239	15	70	452	253	635	4e-13	82.0
rs:WP_044287534	DNA topoisomerase I, partial [Brucella abortus].	26.08	418	239	15	70	452	253	635	4e-13	82.0
rs:WP_043765344	DNA topoisomerase I [Roseivivax isoporae].	25.93	486	265	16	34	454	205	660	4e-13	82.0
rs:WP_032325087	hypothetical protein, partial [Escherichia coli].	36.19	105	67	0	37	141	5	109	4e-13	76.3
tr:A0A0C7C5P2_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.61	460	287	16	18	453	237	651	4e-13	82.0
rs:XP_001902741	DNA topoisomerase III [Brugia malayi].	25.53	329	199	10	69	388	235	526	4e-13	82.0
rs:WP_046961026	DNA topoisomerase I [Dehalococcoides sp. UCH007].	21.60	449	257	12	65	450	245	661	4e-13	82.0
rs:WP_030259285	MULTISPECIES: DNA topoisomerase I [Streptomyces].	26.87	294	164	12	77	354	301	559	4e-13	82.0
rs:XP_007834111	hypothetical protein PFICI_07339 [Pestalotiopsis fici W106-1].	27.74	310	176	10	37	336	254	525	4e-13	82.0
rs:WP_004692239	MULTISPECIES: DNA topoisomerase I [Brucella].	26.68	416	239	15	70	452	253	635	4e-13	82.0
rs:WP_043720005	DNA topoisomerase I [Kutzneria sp. 744].	26.43	367	221	12	38	384	267	604	4e-13	82.0
rs:WP_018811834	DNA topoisomerase I [Salinispora pacifica].	26.07	326	192	12	42	351	261	553	4e-13	82.0
rs:WP_033928613	DNA topoisomerase I [Vibrio cholerae].	26.25	381	227	15	77	446	292	629	4e-13	82.0
rs:WP_041330812	DNA topoisomerase I [Dehalococcoides mccartyi].	21.16	449	259	12	65	450	245	661	4e-13	82.0
rs:WP_004210738	DNA topoisomerase I subunit omega [Klebsiella pneumoniae].	26.84	380	227	15	77	446	284	622	4e-13	82.0
rs:WP_032656725	DNA topoisomerase I [Enterobacter sp. DC1].	26.05	380	230	14	77	446	284	622	4e-13	82.0
rs:WP_040151502	DNA topoisomerase I [Klebsiella pneumoniae].	26.84	380	227	15	77	446	284	622	4e-13	82.0
rs:WP_048267103	DNA topoisomerase I [Klebsiella pneumoniae].	26.84	380	227	15	77	446	284	622	4e-13	82.0
rs:XP_625165	PREDICTED: DNA topoisomerase 3-beta-1-like isoform 2 [Apis mellifera].	24.51	355	224	12	40	385	261	580	4e-13	82.0
rs:WP_034789719	DNA topoisomerase I [Hyphomonas beringensis].	24.37	435	264	14	47	452	231	629	4e-13	82.0
rs:WP_047134706	DNA topoisomerase I [bacterium JGI-5].	23.78	471	269	16	40	452	230	668	4e-13	82.0
rs:WP_040109633	DNA topoisomerase I [Clostridium botulinum].	23.42	427	238	15	77	449	256	647	4e-13	82.0
rs:WP_046672863	DNA topoisomerase I [Sphingobacterium sp. Ag1].	25.90	305	187	8	77	377	250	519	4e-13	82.0
rs:WP_019894900	DNA topoisomerase I [Thiomicrospira halophila].	27.33	322	191	9	47	364	223	505	4e-13	82.0
rs:WP_020875156	DNA topoisomerase I [Desulfococcus multivorans].	24.77	428	260	15	43	449	225	611	4e-13	82.0
tr:G2KTQ4_LACSM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.53	408	254	14	61	452	233	598	4e-13	82.0
rs:WP_028112289	DNA topoisomerase I [Ferrimonas kyonanensis].	25.33	304	179	7	60	354	276	540	4e-13	82.0
rs:WP_026004456	DNA topoisomerase I [Streptomyces sp. AA1529].	25.37	335	194	12	35	354	281	574	4e-13	82.0
rs:WP_002899161	DNA topoisomerase I [Campylobacter jejuni].	25.12	426	247	17	47	450	225	600	4e-13	82.0
rs:WP_038415766	DNA topoisomerase I, partial [Brucella canis].	26.68	416	239	15	70	452	253	635	4e-13	82.0
rs:WP_022423366	DNA topoisomerase [Clostridium sp. CAG:440].	21.70	424	275	10	48	454	227	610	4e-13	82.0
tr:S2J5T0_MUCC1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.70	481	266	20	3	453	241	650	4e-13	82.0
rs:WP_022392632	DNA topoisomerase [Bacteroides intestinalis CAG:315].	25.91	301	183	7	40	334	216	482	4e-13	82.0
rs:WP_012905972	topoisomerase I [Citrobacter rodentium].	25.80	376	236	12	77	446	284	622	4e-13	82.0
rs:WP_021550866	DNA topoisomerase 1 [Escherichia coli].	25.53	376	237	12	77	446	284	622	4e-13	82.0
rs:WP_048224009	DNA topoisomerase I [Citrobacter freundii].	26.06	376	235	12	77	446	284	622	4e-13	82.0
rs:WP_021177330	DNA topoisomerase I [Helicobacter pylori].	26.33	395	227	17	74	450	251	599	4e-13	82.0
rs:WP_017955029	DNA topoisomerase I [actinobacterium SCGC AAA278-O22].	27.22	327	195	10	41	354	251	547	4e-13	82.0
rs:WP_025738670	DNA topoisomerase I [Salinivibrio socompensis].	26.30	384	223	16	77	446	290	627	4e-13	82.0
rs:WP_006460213	DNA topoisomerase I [Thioalkalimicrobium aerophilum].	26.85	298	174	8	43	334	219	478	4e-13	82.0
rs:WP_047066985	DNA topoisomerase I, partial [Enterobacter aerogenes].	25.66	378	234	14	77	446	284	622	4e-13	82.0
rs:WP_010569406	DNA topoisomerase I [Leptospira broomii].	25.50	404	229	13	74	449	249	608	4e-13	81.6
rs:WP_020444080	topoisomerase I [Psychrobacter sp. G].	26.17	363	206	15	40	384	282	600	4e-13	82.0
rs:WP_045336485	DNA topoisomerase I [Enterobacter cloacae].	26.05	380	230	14	77	446	284	622	4e-13	82.0
rs:WP_015366223	DNA topoisomerase I [Enterobacter aerogenes].	25.66	378	234	14	77	446	284	622	4e-13	82.0
rs:WP_048210325	DNA topoisomerase I [Enterobacter cloacae].	26.05	380	230	14	77	446	284	622	4e-13	82.0
rs:WP_009597583	DNA topoisomerase I [Alistipes sp. HGB5].	24.83	302	183	7	47	340	221	486	4e-13	82.0
rs:WP_035463992	DNA topoisomerase I [Bartonella bacilliformis].	25.65	421	246	16	67	452	248	636	4e-13	82.0
rs:WP_000513606	hypothetical protein, partial [Escherichia coli].	27.82	284	166	10	77	356	284	532	4e-13	81.6
rs:WP_045333127	DNA topoisomerase I [Enterobacter cloacae].	26.05	380	230	14	77	446	284	622	4e-13	82.0
rs:WP_041841686	DNA topoisomerase I [Actinoplanes friuliensis].	26.79	377	218	16	47	399	266	608	4e-13	82.0
rs:WP_024468694	DNA topoisomerase I [Treponema pedis].	25.24	420	256	13	50	452	253	631	4e-13	82.0
rs:WP_046565845	DNA topoisomerase I [Micromonospora sp. HK10].	25.00	388	234	14	42	409	261	611	4e-13	82.0
rs:WP_002032552	DNA topoisomerase I [Vibrio cholerae].	26.25	381	227	15	77	446	292	629	4e-13	82.0
rs:WP_023648458	DNA topoisomerase I [Candidatus Pelagibacter ubique].	24.15	443	262	16	46	454	230	632	4e-13	82.0
tr:A0A0F4KQ75_9LACO	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJY48540.1};	23.10	407	258	15	68	457	257	625	4e-13	81.6
rs:WP_032434376	DNA topoisomerase I [Klebsiella pneumoniae].	26.84	380	227	15	77	446	284	622	4e-13	82.0
rs:WP_010355625	DNA topoisomerase I subunit omega [Escherichia sp. TW09231].	25.53	376	237	12	77	446	284	622	4e-13	82.0
rs:WP_005767202	DNA topoisomerase I [Bartonella bacilliformis].	25.65	421	246	16	67	452	248	636	4e-13	82.0
rs:WP_009490010	DNA topoisomerase I [Catellicoccus marimammalium].	23.13	428	259	15	47	452	227	606	4e-13	81.6
gp:CP003784_594	DNA topoisomerase I [Bartonella quintana RM-11]	26.24	423	241	17	67	452	248	636	4e-13	82.0
tr:R7WHZ6_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.94	340	192	12	37	354	236	544	4e-13	82.0
rs:WP_032449857	DNA topoisomerase I [Brucella melitensis].	26.08	418	239	15	70	452	253	635	4e-13	82.0
rs:WP_006810845	MULTISPECIES: topoisomerase I [Enterobacter].	26.05	380	230	14	77	446	284	622	4e-13	82.0
tr:I6H5Q7_SHIFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	26.32	380	229	14	77	446	47	385	4e-13	81.6
rs:WP_015489632	DNA topoisomerase I A [Clavibacter michiganensis].	27.42	372	216	16	30	379	239	578	4e-13	82.0
rs:WP_033346973	DNA topoisomerase I [Streptomyces aureofaciens].	26.87	294	164	12	77	354	301	559	4e-13	82.0
rs:WP_030289386	MULTISPECIES: DNA topoisomerase I [Streptomyces].	26.87	294	164	12	77	354	301	559	4e-13	82.0
rs:WP_045825790	DNA topoisomerase I [Teredinibacter sp. 991H.S.0a.06].	25.12	422	266	13	42	452	261	643	4e-13	82.0
rs:WP_029337611	DNA topoisomerase I [Geodermatophilaceae bacterium URHB0048].	26.67	330	196	11	42	354	290	590	4e-13	82.0
rs:WP_020321645	DNA topoisomerase I [Klebsiella pneumoniae].	26.84	380	227	15	77	446	284	622	4e-13	82.0
rs:WP_044919789	DNA topoisomerase I [Lachnospiraceae bacterium MA2020].	24.54	436	275	13	35	454	218	615	4e-13	81.6
tr:A0A083V3R4_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.68	416	239	15	70	452	262	644	4e-13	82.0
rs:WP_030591020	DNA topoisomerase I [Streptomyces globisporus].	27.24	290	168	10	77	354	301	559	4e-13	82.0
rs:WP_032850977	DNA topoisomerase I [Bacteroides sp. D22].	25.08	315	187	8	36	334	201	482	4e-13	82.0
rs:WP_032478146	DNA topoisomerase I [Vibrio cholerae].	25.65	382	228	15	77	446	292	629	4e-13	82.0
rs:WP_026663998	DNA topoisomerase I [Butyrivibrio sp. AE2015].	23.19	427	265	14	48	454	223	606	4e-13	81.6
rs:WP_018526855	hypothetical protein [Spirochaeta alkalica].	27.13	317	198	9	42	354	253	540	4e-13	82.0
rs:WP_047353322	DNA topoisomerase I [Enterobacter sp. GN02315].	26.05	380	230	14	77	446	284	622	4e-13	82.0
rs:WP_018160535	DNA topoisomerase I [Smaragdicoccus niigatensis].	26.96	293	168	9	77	354	301	562	4e-13	82.0
rs:WP_042676255	DNA topoisomerase I, partial [Xanthomonas fuscans].	26.09	299	183	8	170	459	63	332	4e-13	81.3
rs:WP_002870465	DNA topoisomerase I [Campylobacter jejuni].	25.12	426	247	17	47	450	225	600	4e-13	81.6
tr:A0A0E0GH84_ORYNI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.35	423	262	14	39	435	271	661	4e-13	82.0
rs:WP_030310780	DNA topoisomerase I [Streptomyces sp. NRRL F-6131].	26.53	294	165	12	77	354	301	559	4e-13	82.0
rs:WP_002901763	MULTISPECIES: DNA topoisomerase I [Enterobacteriaceae].	26.84	380	227	15	77	446	284	622	4e-13	82.0
tr:T0KVV8_9NEIS	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQB59647.1}; Flags: Fragment;	28.00	200	135	2	206	396	2	201	4e-13	80.9
rs:WP_041843678	DNA topoisomerase I [Bartonella bacilliformis].	25.65	421	246	16	67	452	248	636	4e-13	82.0
rs:WP_005637485	DNA topoisomerase I [Parabacteroides merdae].	27.81	302	183	9	40	338	213	482	4e-13	82.0
rs:WP_026861812	DNA topoisomerase I [Idiomarina sediminum].	26.75	400	232	17	77	458	290	646	4e-13	82.0
rs:WP_010350249	MULTISPECIES: DNA topoisomerase I subunit omega [Escherichia].	25.53	376	237	12	77	446	284	622	4e-13	82.0
rs:WP_048211498	DNA topoisomerase I [Citrobacter freundii].	26.77	381	226	14	77	446	284	622	4e-13	82.0
rs:WP_014784854	DNA topoisomerase [Terriglobus roseus].	24.64	483	271	19	17	446	190	632	4e-13	82.0
tr:A0A060VRW5_KLEPN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.84	380	227	15	77	446	286	624	4e-13	82.0
rs:WP_020049515	DNA topoisomerase I [Rhizobium leguminosarum].	24.83	439	267	15	47	452	230	638	4e-13	82.0
rs:WP_039698954	hypothetical protein [Clostridium botulinum].	24.03	387	246	12	77	450	282	633	4e-13	82.0
rs:WP_024941857	DNA topoisomerase I [Aeromonas hydrophila].	24.29	420	260	14	49	452	259	636	4e-13	82.0
rs:WP_002867521	DNA topoisomerase I [Campylobacter jejuni].	25.12	426	247	17	47	450	225	600	4e-13	81.6
rs:WP_038154321	DNA topoisomerase I [Trabulsiella guamensis].	26.95	282	167	9	77	354	284	530	4e-13	82.0
rs:WP_007626156	DNA topoisomerase I [Rhizobium sp. CCGE 510].	24.83	439	267	15	47	452	230	638	4e-13	82.0
rs:WP_039425451	DNA topoisomerase I [Vibrio navarrensis].	24.86	358	222	10	40	386	253	574	4e-13	82.0
rs:WP_003833325	MULTISPECIES: topoisomerase I [Citrobacter].	26.06	376	235	12	77	446	284	622	4e-13	82.0
rs:WP_026529492	DNA topoisomerase I [Arthrobacter sanguinis].	26.72	348	207	12	49	377	263	581	4e-13	82.0
rs:WP_040168960	DNA topoisomerase I [Klebsiella pneumoniae].	26.84	380	227	15	77	446	284	622	4e-13	82.0
rs:WP_013366501	topoisomerase I [Enterobacter lignolyticus].	26.11	383	226	14	77	446	284	622	4e-13	82.0
rs:WP_023316755	DNA topoisomerase 1 [Klebsiella pneumoniae].	26.84	380	227	15	77	446	284	622	4e-13	82.0
rs:WP_012044745	DNA topoisomerase I [Bradyrhizobium sp. BTAi1].	25.41	429	251	15	60	454	243	636	4e-13	82.0
rs:WP_042385490	MULTISPECIES: DNA topoisomerase I [Clostridium].	22.72	427	241	14	77	449	256	647	4e-13	81.6
rs:WP_017372301	topoisomerase I [Enterobacteriaceae bacterium LSJC7].	27.62	286	164	8	77	356	287	535	4e-13	82.0
rs:WP_047999746	DNA topoisomerase I [Lactobacillus sp. TCF032-E4].	23.57	403	227	16	77	452	285	633	4e-13	81.6
rs:WP_005647008	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	27.81	302	183	9	40	338	213	482	4e-13	81.6
rs:WP_003985132	DNA topoisomerase I [Escherichia coli].	25.80	376	236	12	77	446	284	622	4e-13	82.0
rs:WP_031158108	DNA topoisomerase I [Streptosporangium roseum].	26.79	336	198	12	37	354	249	554	4e-13	82.0
rs:WP_009347727	DNA topoisomerase I [Alloprevotella rava].	27.76	263	154	7	77	335	250	480	4e-13	81.6
gp:CP009099_529	DNA topoisomerase I [Brucella abortus]	26.08	418	239	15	70	452	262	644	4e-13	82.0
rs:WP_042024775	DNA topoisomerase I [Aeromonas enteropelogenes].	24.58	419	260	14	49	452	259	636	4e-13	82.0
tr:H2Z237_CIOSA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.73	377	223	13	39	400	293	627	4e-13	81.6
rs:WP_002913205	DNA topoisomerase I [Campylobacter jejuni].	24.77	440	258	18	41	458	219	607	4e-13	81.6
rs:WP_022321949	DNA topoisomerase [Parabacteroides merdae CAG:48].	27.81	302	183	9	40	338	213	482	4e-13	81.6
rs:WP_018727569	DNA topoisomerase I [Salinispora pacifica].	26.07	326	192	12	42	351	261	553	4e-13	82.0
rs:WP_022623213	topoisomerase I [Pantoea ananatis].	25.84	387	239	13	77	452	284	633	4e-13	82.0
rs:WP_044132021	DNA topoisomerase I, partial [Bacteroides fragilis].	25.40	315	186	8	36	334	152	433	4e-13	81.3
rs:WP_023805302	DNA topoisomerase I [Mesorhizobium sp. L2C089B000].	25.34	446	257	18	45	452	228	635	4e-13	82.0
rs:WP_014178442	DNA topoisomerase I [Streptomyces bingchenggensis].	25.61	328	195	11	42	354	264	557	4e-13	82.0
rs:WP_002803036	DNA topoisomerase I [Campylobacter coli].	25.00	432	252	17	41	450	219	600	4e-13	81.6
rs:XP_749401	DNA topoisomerase III [Aspergillus fumigatus Af293].	25.38	331	191	8	45	358	267	558	4e-13	81.6
rs:WP_017781938	topoisomerase I [Aeromonas hydrophila].	24.29	420	260	14	49	452	259	636	4e-13	82.0
tr:K2D6X4_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EKD82339.1}; Flags: Fragment;	25.93	297	181	10	166	452	62	329	4e-13	81.3
rs:WP_002549474	DNA topoisomerase I [Propionibacterium acnes].	25.97	385	227	16	30	388	238	590	4e-13	82.0
rs:WP_040775025	DNA topoisomerase I [Rhodococcus rhodnii].	27.94	340	192	12	37	354	259	567	4e-13	82.0
rs:WP_012097495	DNA topoisomerase I [Anaeromyxobacter sp. Fw109-5].	23.66	448	269	16	41	452	255	665	4e-13	81.6
rs:WP_034089608	DNA topoisomerase I [Streptacidiphilus albus].	26.54	324	187	12	77	380	300	592	4e-13	82.0
rs:WP_041817766	DNA topoisomerase I [Lactobacillus sanfranciscensis].	23.53	408	254	14	61	452	259	624	4e-13	81.6
rs:WP_018827719	DNA topoisomerase I [Salinispora pacifica].	26.07	326	192	12	42	351	261	553	4e-13	82.0
tr:D4T0H8_9XANT	SubName: Full=Topoisomerase I {ECO:0000313|EMBL:EFF42037.1};	26.09	299	183	8	170	459	43	312	4e-13	81.3
tr:F9Q4Y2_STROR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.46	358	219	9	60	401	230	548	4e-13	81.3
rs:WP_027646567	DNA topoisomerase I [Salinispora pacifica].	26.07	326	192	12	42	351	261	553	4e-13	82.0
rs:XP_010760449	hypothetical protein PADG_04954 [Paracoccidioides brasiliensis Pb18].	25.87	317	181	9	73	369	294	576	5e-13	81.6
rs:WP_013320619	DNA topoisomerase I [Cyanothece sp. PCC 7822].	25.38	457	259	20	29	452	224	631	5e-13	81.6
rs:WP_045393156	DNA topoisomerase I [Enterobacter aerogenes].	25.66	378	234	14	77	446	284	622	5e-13	82.0
rs:WP_018354201	DNA topoisomerase I [Mycobacterium hassiacum].	26.44	329	196	9	41	354	268	565	5e-13	82.0
rs:WP_031090918	DNA topoisomerase I [Streptomyces sp. NRRL S-15].	26.90	290	169	10	77	354	299	557	5e-13	82.0
rs:WP_044573128	DNA topoisomerase I [Streptomyces iranensis].	25.00	328	197	11	42	354	266	559	5e-13	82.0
tr:A0A075AT24_9FUNG	SubName: Full=DNA topoisomerase, type IA, central domain-containing protein {ECO:0000313|EMBL:EPZ33325.1};	24.73	372	223	14	22	377	510	840	5e-13	82.0
sp:TOP1_CAMJE	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.12	426	247	17	47	450	225	600	5e-13	81.6
rs:WP_022648322	MULTISPECIES: DNA topoisomerase 1 [Enterobacter].	26.05	380	230	14	77	446	284	622	5e-13	81.6
rs:WP_026256666	DNA topoisomerase I [Mycobacterium sp. 155].	26.25	381	228	11	41	399	271	620	5e-13	82.0
rs:WP_004804488	hypothetical protein, partial [Eggerthia catenaformis].	32.24	183	105	4	202	380	13	180	5e-13	78.2
rs:WP_046870408	DNA topoisomerase I [Clostridium sporogenes].	23.42	427	238	15	77	449	256	647	5e-13	81.6
rs:WP_005459856	DNA topoisomerase I [Saccharomonospora cyanea].	26.63	368	221	12	37	384	268	606	5e-13	82.0
rs:WP_023688317	DNA topoisomerase I [Mesorhizobium sp. LSJC269B00].	25.34	446	257	18	45	452	228	635	5e-13	81.6
rs:WP_018819085	DNA topoisomerase I [Salinispora pacifica].	26.07	326	192	12	42	351	261	553	5e-13	82.0
rs:WP_027649962	DNA topoisomerase I [Salinispora pacifica].	26.07	326	192	12	42	351	261	553	5e-13	82.0
rs:WP_000681510	DNA topoisomerase I [Helicobacter pylori].	25.25	396	230	16	74	450	251	599	5e-13	81.6
tr:G0UCD3_TRYVY	SubName: Full=Putative DNA topoisomerase III {ECO:0000313|EMBL:CCC53485.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CCC53485.1};	23.09	433	271	15	39	453	191	579	5e-13	81.6
rs:WP_010801879	MULTISPECIES: DNA topoisomerase I [Parabacteroides].	26.96	345	211	13	65	384	239	567	5e-13	81.6
rs:WP_045923410	DNA topoisomerase I [Lactobacillus mellis].	22.52	404	260	14	69	457	267	632	5e-13	81.6
rs:WP_027044695	DNA topoisomerase I [Mesorhizobium sp. URHC0008].	25.56	450	259	19	41	452	224	635	5e-13	81.6
rs:WP_041691324	hypothetical protein, partial [Elusimicrobium minutum].	25.84	418	242	15	58	450	249	623	5e-13	81.6
rs:WP_028078437	DNA topoisomerase I [Solobacterium moorei].	25.55	407	233	15	69	452	247	606	5e-13	81.6
tr:C4IVM3_BRUAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.08	418	239	15	70	452	277	659	5e-13	81.6
tr:J7T930_CLOSG	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.72	427	241	14	77	449	260	651	5e-13	81.6
rs:WP_030299335	DNA topoisomerase I [Streptomyces katrae].	26.62	293	166	11	77	354	298	556	5e-13	81.6
tr:D4C6E9_9CLOT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EFE14137.1};	37.41	147	76	4	302	445	12	145	5e-13	78.2
rs:WP_009360140	DNA topoisomerase I [alpha proteobacterium HIMB114].	25.92	436	260	14	51	454	234	638	5e-13	81.6
rs:WP_039709081	DNA topoisomerase I [Actinobacillus pleuropneumoniae].	25.30	411	254	16	47	446	261	629	5e-13	81.6
rs:WP_030152667	DNA topoisomerase I [Streptomyces sp. NRRL S-244].	26.62	293	166	11	77	354	298	556	5e-13	81.6
rs:WP_026422883	DNA topoisomerase I [Actinokineospora inagensis].	25.83	360	210	12	41	378	269	593	5e-13	81.6
tr:F3K993_PSEAJ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGH93755.1}; Flags: Fragment;	36.96	138	78	2	315	452	15	143	5e-13	77.4
rs:WP_030225040	DNA topoisomerase I [Streptomyces sp. NRRL WC-3626].	27.30	293	164	11	77	354	299	557	5e-13	81.6
rs:WP_028909395	DNA topoisomerase I [Prevotella sp. AGR2160].	27.82	266	155	9	77	338	251	483	5e-13	81.6
rs:WP_028192777	DNA topoisomerase I [Salinispora pacifica].	26.07	326	192	12	42	351	261	553	5e-13	81.6
rs:WP_004307878	DNA topoisomerase I [Bacteroides ovatus].	25.08	315	187	8	36	334	201	482	5e-13	81.6
rs:WP_000520434	topoisomerase I [Vibrio cholerae].	26.25	381	227	15	77	446	292	629	5e-13	81.6
rs:WP_042318669	DNA topoisomerase I [Citrobacter farmeri].	25.53	376	237	12	77	446	284	622	5e-13	81.6
rs:WP_039334683	DNA topoisomerase I [Pantoea rodasii].	27.58	330	175	12	77	386	284	569	5e-13	81.6
rs:WP_040176843	DNA topoisomerase I [Leuconostoc citreum].	23.77	446	258	18	36	452	235	627	5e-13	81.6
rs:WP_018222494	DNA topoisomerase I [Salinispora pacifica].	26.07	326	192	12	42	351	261	553	5e-13	81.6
rs:WP_000259053	DNA topoisomerase III [Streptococcus agalactiae].	24.81	395	244	12	18	399	223	577	5e-13	81.3
tr:N1M7K9_9NOCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	25.99	327	200	9	41	354	1	298	5e-13	81.6
sp:TOP1_SYNE7	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	27.16	313	185	10	41	346	249	525	5e-13	81.6
rs:WP_008753063	DNA topoisomerase I [Lachnoanaerobaculum saburreum].	22.78	439	280	12	34	454	214	611	5e-13	81.6
tr:K5BE85_9MYCO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.44	329	196	9	41	354	255	552	5e-13	81.6
rs:WP_023691166	MULTISPECIES: DNA topoisomerase I [Mesorhizobium].	25.34	446	257	18	45	452	228	635	5e-13	81.6
rs:WP_017646907	DNA topoisomerase [Streptococcus agalactiae].	26.65	334	203	9	74	399	278	577	5e-13	81.3
rs:WP_015078479	DNA topoisomerase I [Anabaena sp. 90].	25.40	437	265	17	28	443	225	621	5e-13	81.6
rs:WP_033379005	MULTISPECIES: DNA topoisomerase I, partial [Mycoplasma].	25.53	380	212	13	91	450	266	594	5e-13	81.3
rs:WP_034495665	DNA topoisomerase I [Buttiauxella agrestis].	25.13	378	236	12	77	446	284	622	5e-13	81.6
tr:A0A084BGY4_ASPFM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.38	331	191	8	45	358	267	558	5e-13	81.3
rs:WP_028135920	DNA topoisomerase I [Bradyrhizobium japonicum].	24.59	423	256	13	61	452	244	634	5e-13	81.6
rs:WP_019034424	DNA topoisomerase I [Peptoniphilus lacrimalis].	22.41	424	275	11	45	454	226	609	5e-13	81.6
rs:WP_046155113	DNA topoisomerase I [Citrobacter freundii].	25.80	376	236	12	77	446	284	622	5e-13	81.6
rs:WP_017959963	DNA topoisomerase I [Rhizobium leguminosarum].	25.23	440	264	15	47	452	230	638	5e-13	81.6
rs:WP_044278477	DNA topoisomerase I [Campylobacter jejuni].	25.12	426	247	17	47	450	225	600	5e-13	81.6
rs:WP_022960093	topoisomerase I [Spongiibacter tropicus].	25.77	388	237	13	77	452	295	643	5e-13	81.6
rs:WP_020129311	DNA topoisomerase I [Streptomyces sp. 303MFCol5.2].	25.73	342	198	12	35	354	250	557	5e-13	81.6
rs:WP_011514221	topoisomerase I [Psychrobacter cryohalolentis].	26.17	363	206	15	40	384	282	600	5e-13	81.6
rs:WP_040243794	DNA topoisomerase I [Klebsiella pneumoniae].	26.84	380	227	15	77	446	284	622	5e-13	81.6
rs:XP_008766140	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Rattus norvegicus].	27.56	312	173	11	166	455	366	646	5e-13	81.6
rs:WP_040627511	DNA topoisomerase I [Solobacterium moorei].	25.55	407	233	15	69	452	247	606	5e-13	81.6
rs:WP_013025933	topoisomerase I [Pantoea ananatis].	25.84	387	239	13	77	452	284	633	5e-13	81.6
rs:WP_048291530	DNA topoisomerase I [Klebsiella pneumoniae].	26.84	380	227	15	77	446	284	622	5e-13	81.6
rs:WP_006378418	DNA topoisomerase I [Streptomyces turgidiscabies].	27.30	293	164	11	77	354	299	557	5e-13	81.6
rs:WP_017281509	DNA topoisomerase I [Helicobacter pylori].	25.32	395	231	16	74	450	251	599	5e-13	81.6
tr:D7IZD4_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.08	315	187	8	36	334	211	492	5e-13	81.6
rs:WP_027658068	DNA topoisomerase I [Salinispora pacifica].	26.07	326	192	12	42	351	261	553	5e-13	81.6
rs:WP_034942599	DNA topoisomerase I [Geodermatophilaceae bacterium URHB0062].	25.98	358	215	12	42	378	290	618	5e-13	81.6
rs:WP_044867927	DNA topoisomerase I, partial [Enterobacter cloacae].	27.66	282	165	10	77	354	284	530	5e-13	81.3
rs:WP_024351714	DNA topoisomerase I [Aurantimonas coralicida].	25.95	447	255	16	47	452	230	641	5e-13	81.6
rs:WP_032622442	DNA topoisomerase I [Lelliottia amnigena].	26.05	380	230	14	77	446	284	622	5e-13	81.6
rs:WP_030205944	DNA topoisomerase I [Streptomyces bikiniensis].	26.62	293	166	11	77	354	299	557	5e-13	81.6
rs:WP_019221809	DNA topoisomerase I [Bartonella senegalensis].	26.57	429	242	18	61	452	244	636	5e-13	81.6
rs:WP_023734453	DNA topoisomerase I [Mesorhizobium sp. LNJC403B00].	25.34	446	257	18	45	452	228	635	5e-13	81.6
rs:WP_036634295	DNA topoisomerase I, partial [Paenirhodobacter enshiensis].	26.56	433	256	14	47	454	228	623	5e-13	81.6
rs:WP_034211709	DNA topoisomerase I [Arenimonas metalli].	29.04	334	188	13	66	380	254	557	5e-13	81.6
tr:A0A0E9B7U5_PANAN	SubName: Full=DNA topoisomerase 1 (ECO:0000255|HAMAP-Rule:MF_00952) {ECO:0000313|EMBL:CRH29524.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRH29524.1};	25.84	387	239	13	77	452	284	633	5e-13	81.6
rs:WP_028722826	DNA topoisomerase I [Pantoea ananatis].	25.84	387	239	13	77	452	284	633	5e-13	81.6
rs:WP_023300259	DNA topoisomerase 1 [Enterobacter cloacae].	26.05	380	230	14	77	446	284	622	5e-13	81.6
rs:WP_018069492	DNA topoisomerase I [Rhizobium leguminosarum].	24.83	439	267	15	47	452	230	638	5e-13	81.6
rs:WP_005612814	DNA topoisomerase I [Ruminococcus lactaris].	24.88	426	266	12	48	457	227	614	5e-13	81.6
rs:WP_043972525	DNA topoisomerase I [Novosphingobium sp. P6W].	26.21	435	261	17	41	452	222	619	5e-13	81.6
rs:WP_029584712	DNA topoisomerase I [Bradyrhizobium sp. URHD0069].	25.28	439	270	12	45	454	228	637	5e-13	81.6
rs:XP_001740725	DNA topoisomerase 3-beta-1 [Entamoeba dispar SAW760].	23.91	368	235	13	47	399	262	599	5e-13	81.6
rs:WP_039141172	DNA topoisomerase I [Flavihumibacter solisilvae].	25.00	316	205	8	28	340	204	490	5e-13	81.6
rs:WP_036324537	DNA topoisomerase I [Microbispora sp. ATCC PTA-5024].	27.56	312	182	12	77	374	297	578	5e-13	81.6
rs:WP_017707944	hypothetical protein [Pseudomonas syringae].	25.24	416	246	17	50	446	222	591	5e-13	81.3
rs:WP_027300609	DNA topoisomerase I [Rhodospirillales bacterium URHD0088].	25.53	423	246	16	65	454	250	636	5e-13	81.6
rs:WP_043221100	DNA topoisomerase I [Streptomyces sp. NRRL F-5193].	26.62	293	166	11	77	354	299	557	5e-13	81.6
rs:WP_046733332	DNA topoisomerase I [Streptomyces sp. MUSC119T].	27.30	293	164	11	77	354	299	557	5e-13	81.6
rs:WP_006842975	DNA topoisomerase I [Dysgonomonas mossii].	28.24	262	152	6	77	334	252	481	5e-13	81.6
rs:WP_008856759	DNA topoisomerase I [Lactobacillus kisonensis].	24.70	417	249	16	55	452	254	624	5e-13	81.6
rs:WP_026668681	DNA topoisomerase I [Butyrivibrio sp. AE3009].	23.74	417	263	12	54	454	230	607	5e-13	81.3
rs:WP_005742386	DNA topoisomerase III [Pseudomonas amygdali].	23.37	338	197	11	61	349	313	637	5e-13	81.6
rs:WP_021853268	DNA topoisomerase [Prevotella sp. CAG:1058].	26.11	337	209	11	23	353	199	501	5e-13	81.6
rs:WP_004582047	DNA topoisomerase I subunit omega [Marinobacter nanhaiticus].	24.55	391	246	13	68	446	281	634	5e-13	81.6
tr:F5SPD8_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.84	339	193	13	61	384	289	587	5e-13	81.6
rs:WP_038229912	DNA topoisomerase I [Xylella fastidiosa].	26.53	392	227	16	53	413	241	602	5e-13	81.6
rs:WP_039964959	DNA topoisomerase I [Veillonella sp. 6_1_27].	22.84	416	280	10	47	454	295	677	5e-13	81.6
rs:WP_030755950	MULTISPECIES: DNA topoisomerase I [Streptomyces].	26.62	293	166	11	77	354	298	556	5e-13	81.6
rs:WP_004344384	DNA topoisomerase I [Prevotella buccae].	27.65	264	152	8	77	334	252	482	5e-13	81.6
rs:WP_037509240	hypothetical protein, partial [Sphingomonas sp. BHC-A].	28.42	292	162	10	74	350	1	260	5e-13	79.0
rs:WP_002888820	DNA topoisomerase I [Campylobacter jejuni].	25.12	426	247	17	47	450	225	600	5e-13	81.3
tr:E6N9Z0_9ARCH	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:BAJ49146.1}; EC=5.99.1.2 {ECO:0000313|EMBL:BAJ49146.1};	26.19	336	201	12	53	381	253	548	5e-13	81.3
rs:WP_026317155	DNA topoisomerase I [Ahrensia kielensis].	25.53	427	256	13	60	452	241	639	6e-13	81.6
tr:W7KLC0_9CREN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.99	289	168	10	73	354	275	527	6e-13	81.3
tr:E7MMK8_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.55	407	233	15	69	452	258	617	6e-13	81.3
rs:WP_046401192	DNA topoisomerase I [Lactococcus garvieae].	22.88	437	274	13	34	452	239	630	6e-13	81.3
rs:WP_025651317	MULTISPECIES: DNA topoisomerase I [Psychrobacter].	25.92	436	247	22	40	452	274	656	6e-13	81.6
tr:D6KN24_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.84	416	280	10	47	454	251	633	6e-13	81.3
tr:A0A087GDY2_ARAAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.89	462	287	17	18	451	246	675	6e-13	81.6
rs:XP_005464354	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Oreochromis niloticus].	22.45	441	262	15	40	453	252	639	6e-13	81.6
rs:WP_038430708	DNA topoisomerase I [Mycobacterium avium].	25.13	394	235	12	35	399	257	619	6e-13	81.6
rs:WP_027522980	DNA topoisomerase I [Bradyrhizobium sp. Ec3.3].	23.98	417	248	14	70	452	253	634	6e-13	81.6
tr:A0A0A6JT51_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KHC52303.1};	26.11	337	202	10	56	378	275	578	6e-13	81.3
rs:WP_042072215	DNA topoisomerase I [Aeromonas enteropelogenes].	24.58	419	260	14	49	452	259	636	6e-13	81.6
tr:A0A078LGR5_CITKO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.53	380	232	14	77	446	284	622	6e-13	81.6
rs:WP_037364714	DNA topoisomerase I [Selenomonas ruminantium].	25.00	440	261	15	41	456	248	642	6e-13	81.3
rs:WP_030019286	DNA topoisomerase I [Streptomyces monomycini].	25.62	324	200	10	42	354	266	559	6e-13	81.6
rs:WP_037955360	DNA topoisomerase I [Streptomyces sp. PRh5].	25.00	328	197	11	42	354	282	575	6e-13	81.6
rs:WP_011770299	topoisomerase I [Psychromonas ingrahamii].	26.96	382	225	17	77	446	292	631	6e-13	81.6
rs:WP_036728588	DNA topoisomerase I [Peptoniphilus sp. ChDC B134].	25.64	433	231	17	69	449	251	644	6e-13	81.3
rs:WP_046418721	DNA topoisomerase I [Xylella fastidiosa].	26.53	392	227	16	53	413	241	602	6e-13	81.6
rs:WP_030828008	DNA topoisomerase I [Streptomyces sp. NRRL F-2305].	27.30	293	164	11	77	354	299	557	6e-13	81.6
rs:WP_029558610	DNA topoisomerase I [Xanthobacter sp. 91].	28.44	422	229	18	69	454	253	637	6e-13	81.6
rs:WP_031520179	DNA topoisomerase I [Streptomyces sp. NRRL F-5123].	27.21	294	163	12	77	354	302	560	6e-13	81.6
rs:WP_004697212	DNA topoisomerase I [Veillonella parvula].	23.04	421	273	13	47	454	295	677	6e-13	81.3
rs:WP_005312182	topoisomerase I [Aeromonas salmonicida].	25.00	420	257	15	49	452	259	636	6e-13	81.6
rs:WP_004008771	DNA topoisomerase I [Mobiluncus curtisii].	27.41	332	191	12	45	356	264	565	6e-13	81.6
rs:WP_045374699	DNA topoisomerase I [Enterobacter aerogenes].	25.66	378	234	14	77	446	284	622	6e-13	81.6
rs:WP_015508496	hypothetical protein [Rickettsia prowazekii].	24.46	413	249	16	65	449	250	627	6e-13	81.3
rs:WP_022043898	DNA topoisomerase [Alistipes finegoldii CAG:68].	24.92	301	182	7	47	339	221	485	6e-13	81.3
tr:A0A0A6KR82_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KHC63786.1};	26.11	337	202	10	56	378	275	578	6e-13	81.3
rs:WP_046690637	DNA topoisomerase I [Leptospira santarosai].	24.03	437	261	17	40	450	211	602	6e-13	81.3
rs:WP_004323870	MULTISPECIES: DNA topoisomerase I [Bacteroides].	25.40	315	186	8	36	334	201	482	6e-13	81.3
rs:WP_040966555	DNA topoisomerase I [Campylobacter jejuni].	25.35	434	251	18	47	458	225	607	6e-13	81.3
rs:WP_030353279	DNA topoisomerase I [Streptomyces scopuliridis].	25.00	324	202	10	42	354	264	557	6e-13	81.6
rs:WP_004112425	topoisomerase I [Klebsiella oxytoca].	26.25	381	228	15	77	446	284	622	6e-13	81.6
rs:WP_009197744	DNA topoisomerase I [Actinomyces sp. oral taxon 848].	26.78	366	214	13	47	389	256	590	6e-13	81.6
rs:WP_028828555	DNA topoisomerase III [Proteocatella sphenisci].	22.77	448	263	14	43	450	263	667	6e-13	81.3
tr:W5UTM6_9MOLU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.53	380	212	13	91	450	266	594	6e-13	81.3
rs:WP_030184011	DNA topoisomerase I [Streptomyces violaceorubidus].	26.96	293	165	11	77	354	316	574	6e-13	81.6
rs:WP_029570068	DNA topoisomerase I [Pantoea ananatis].	25.32	387	241	12	77	452	284	633	6e-13	81.6
rs:WP_024562448	MULTISPECIES: DNA topoisomerase I [Enterobacteriaceae].	26.49	385	222	17	77	446	284	622	6e-13	81.6
rs:WP_012676889	DNA topoisomerase I [Persephonella marina].	23.02	378	218	8	2	354	177	506	6e-13	81.3
rs:WP_044297986	DNA topoisomerase I [Psychrobacter sp. 1501(2011)].	27.14	339	192	14	61	384	292	590	6e-13	81.6
tr:A0A0A4BUN0_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGU27326.1};	26.11	337	202	10	56	378	275	578	6e-13	81.3
tr:A0A0A6KX97_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KHC36800.1};	26.11	337	202	10	56	378	275	578	6e-13	81.3
rs:WP_029701702	DNA topoisomerase I [Clostridium sp. ASBs410].	23.89	427	268	13	48	457	230	616	6e-13	81.3
rs:WP_028013404	DNA topoisomerase I [Enterobacter cloacae].	27.05	281	168	8	77	354	284	530	6e-13	81.6
rs:WP_037187887	DNA topoisomerase I [Rhodococcus fascians].	26.38	326	200	10	41	354	265	562	6e-13	81.6
rs:WP_048476307	DNA topoisomerase I [Streptomyces roseus].	26.62	293	166	11	77	354	298	556	6e-13	81.6
rs:WP_030554443	DNA topoisomerase I [Streptomyces exfoliatus].	26.62	293	166	11	77	354	299	557	6e-13	81.6
rs:WP_030012191	DNA topoisomerase I [Streptomyces lavendulae].	26.62	293	166	11	77	354	298	556	6e-13	81.6
rs:WP_026893862	DNA topoisomerase I [Clostridiisalibacter paucivorans].	22.45	432	267	15	48	457	229	614	6e-13	81.3
rs:WP_010702397	DNA topoisomerase I [Bartonella bovis].	26.08	418	248	15	67	452	248	636	6e-13	81.3
rs:WP_025236016	DNA topoisomerase I [Mannheimia varigena].	26.65	379	229	15	77	446	290	628	6e-13	81.6
rs:WP_039006187	DNA topoisomerase I [Xanthomonas translucens].	29.57	301	166	11	66	350	254	524	6e-13	81.3
rs:WP_011531122	DNA topoisomerase I [Deinococcus geothermalis].	25.85	325	190	11	37	344	247	537	6e-13	81.6
rs:WP_040054253	DNA topoisomerase I [Candidatus Atelocyanobacterium thalassa].	26.88	320	198	10	66	377	275	566	6e-13	81.3
tr:C4FQQ5_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.65	427	263	14	47	454	298	680	6e-13	81.3
tr:A0A0D0B157_9HOMO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.10	381	243	11	22	387	234	579	6e-13	81.6
gp:HG803176_586	topA gene product [Brucella canis str. Oliveri]	26.68	416	239	15	70	452	253	635	6e-13	81.6
rs:WP_013499649	DNA topoisomerase I [Ruminococcus albus].	24.08	436	264	15	41	452	219	611	6e-13	81.3
rs:WP_004603702	DNA topoisomerase I [[Eubacterium] cellulosolvens].	25.06	423	258	13	53	457	232	613	6e-13	81.3
rs:WP_006111841	DNA topoisomerase I [Halorubrum coriense].	24.68	466	268	17	35	454	242	670	6e-13	81.3
rs:WP_024052236	DNA topoisomerase [Streptococcus anginosus].	24.49	343	223	9	60	397	264	575	6e-13	80.9
rs:WP_004341311	MULTISPECIES: DNA topoisomerase I [Prevotella].	27.65	264	152	8	77	334	252	482	6e-13	81.3
rs:WP_031572738	DNA topoisomerase I [Proteiniclasticum ruminis].	24.10	415	248	15	60	452	237	606	6e-13	81.3
rs:WP_005475914	topA protein [Streptomyces bottropensis].	26.96	293	165	11	77	354	299	557	6e-13	81.6
tr:A0A0A4BNW5_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGU11439.1};	26.11	337	202	10	56	378	275	578	6e-13	81.3
rs:WP_017411764	topoisomerase I [Aeromonas salmonicida].	25.00	420	257	15	49	452	259	636	6e-13	81.3
rs:WP_042677941	DNA topoisomerase I, partial [Pantoea sp. B40].	25.84	387	239	13	77	452	93	442	6e-13	81.3
tr:A0A061Q1G5_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.39	386	224	13	77	446	291	628	6e-13	81.3
rs:WP_002882239	DNA topoisomerase I [Campylobacter jejuni].	25.12	426	247	17	47	450	225	600	6e-13	81.3
rs:WP_012968444	topoisomerase I [Klebsiella variicola].	26.23	385	223	14	77	446	284	622	6e-13	81.3
rs:WP_032647574	MULTISPECIES: DNA topoisomerase I [Enterobacter].	25.79	380	231	14	77	446	284	622	6e-13	81.3
tr:S7ZP59_PENO1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.00	336	186	8	45	358	266	557	6e-13	81.3
rs:WP_032395241	DNA topoisomerase I [Rhodococcus fascians].	26.38	326	200	10	41	354	265	562	6e-13	81.6
rs:WP_045198457	DNA topoisomerase I [Rhodococcus sp. B7740].	26.38	326	200	10	41	354	265	562	6e-13	81.6
rs:WP_021952695	DNA topoisomerase [Eubacterium sp. CAG:161].	23.19	427	272	10	48	457	225	612	6e-13	81.3
rs:WP_022195275	DNA topoisomerase [Azospirillum sp. CAG:239].	27.98	436	250	17	47	454	228	627	6e-13	81.3
rs:WP_004052455	DNA topoisomerase I [Eubacterium plexicaudatum].	24.94	409	253	12	65	457	245	615	6e-13	81.3
rs:WP_039626232	DNA topoisomerase I [Vibrio ichthyoenteri].	26.78	407	227	17	62	446	270	627	6e-13	81.3
rs:WP_022065862	DNA topoisomerase [Klebsiella variicola CAG:634].	26.23	385	223	14	77	446	284	622	6e-13	81.3
tr:B2KBN6_ELUMP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.84	418	242	15	58	450	270	644	6e-13	81.3
rs:WP_005441649	topoisomerase I [Vibrio harveyi].	25.65	386	223	13	77	446	291	628	6e-13	81.3
tr:W1FGI9_ENTCL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	26.05	380	230	14	77	446	89	427	6e-13	81.3
rs:WP_030209244	DNA topoisomerase I [Streptomyces griseoluteus].	26.62	293	166	11	77	354	299	557	6e-13	81.6
rs:WP_048199772	DNA topoisomerase I [Sulfolobales archaeon AZ1].	25.93	324	197	10	38	354	242	529	6e-13	81.3
tr:A0A061IZH5_TRYRA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.05	358	204	13	85	427	297	619	6e-13	81.3
rs:WP_027700506	DNA topoisomerase I [Xylella fastidiosa].	26.53	392	227	16	53	413	241	602	6e-13	81.3
rs:WP_013472919	DNA topoisomerase I [Mycobacterium gilvum].	25.93	378	226	13	55	410	282	627	6e-13	81.3
rs:WP_030709415	DNA topoisomerase I [Streptomyces sp. NRRL F-2580].	26.62	293	166	11	77	354	298	556	6e-13	81.3
rs:WP_009341807	DNA topoisomerase I [Raphidiopsis brookii].	25.99	354	227	9	41	387	249	574	6e-13	81.3
rs:WP_024907119	MULTISPECIES: DNA topoisomerase I [Enterobacter cloacae complex].	25.79	380	231	14	77	446	284	622	6e-13	81.3
tr:K1DZM7_9MICO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.45	344	203	10	25	350	230	541	6e-13	81.6
rs:WP_036480850	DNA topoisomerase I [Nitratireductor basaltis].	23.39	436	268	14	47	449	230	632	6e-13	81.3
tr:C4YQM8_CANAW	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEQ44517.1};	26.11	337	202	10	56	378	275	578	6e-13	81.3
tr:A0A0A4AHV5_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGU10901.1};	26.11	337	202	10	56	378	275	578	6e-13	81.3
rs:WP_042054514	DNA topoisomerase I [Aeromonas veronii].	24.76	420	258	15	49	452	259	636	6e-13	81.3
rs:WP_005334892	topoisomerase I [Aeromonas veronii].	24.76	420	258	15	49	452	259	636	6e-13	81.3
rs:WP_043012938	DNA topoisomerase 1 [Campylobacter jejuni].	25.12	426	247	17	47	450	225	600	6e-13	81.3
rs:WP_008502813	MULTISPECIES: topoisomerase I [Enterobacter].	25.84	445	272	18	13	446	225	622	6e-13	81.3
rs:WP_004101389	MULTISPECIES: topoisomerase I [Klebsiella].	26.25	381	228	15	77	446	284	622	6e-13	81.3
rs:WP_046619715	DNA topoisomerase I [Enterobacter cloacae].	26.05	380	230	14	77	446	284	622	6e-13	81.3
sp:TOP1_RICPR	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.46	413	249	16	65	449	250	627	6e-13	81.3
rs:WP_036223571	hypothetical protein [Mesoaciditoga lauensis].	24.40	373	218	10	74	426	249	577	6e-13	81.3
tr:A0A0A3DLK3_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGR10128.1};	26.11	337	202	10	56	378	275	578	6e-13	81.3
tr:A0A0A4C4G6_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGU30711.1};	26.11	337	202	10	56	378	275	578	6e-13	81.3
tr:A0A0A3CMN4_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGQ98297.1};	26.11	337	202	10	56	378	275	578	6e-13	81.3
tr:X0R4V8_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.90	363	207	15	40	384	274	592	6e-13	81.3
rs:WP_022747953	DNA topoisomerase I [Lachnobacterium bovis].	23.57	420	269	10	48	452	227	609	6e-13	81.3
rs:WP_002531648	DNA topoisomerase I [Propionibacterium acnes].	25.07	383	233	13	30	388	238	590	6e-13	81.3
rs:WP_023344331	MULTISPECIES: DNA topoisomerase 1 [Enterobacter cloacae complex].	25.79	380	231	14	77	446	284	622	6e-13	81.3
rs:WP_044175323	DNA topoisomerase I [Photobacterium damselae].	26.51	381	226	16	77	446	291	628	6e-13	81.3
rs:WP_022360248	DNA topoisomerase [Clostridium sp. CAG:43].	26.87	402	235	14	74	457	264	624	6e-13	81.3
rs:WP_027890873	DNA topoisomerase I [Megamonas hypermegale].	23.39	436	261	16	47	457	237	624	6e-13	81.3
rs:WP_021127600	DNA topoisomerase III [[Clostridium] sordellii].	24.52	314	206	11	49	357	252	539	6e-13	81.3
tr:Q4EA11_9RICK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.54	373	209	14	106	452	16	349	6e-13	80.9
rs:WP_006191226	DNA topoisomerase I [Selenomonas sputigena].	25.63	437	245	18	49	457	340	724	6e-13	81.3
rs:WP_031080986	DNA topoisomerase I [Streptomyces sp. NRRL WC-3549].	27.43	288	170	10	77	354	301	559	6e-13	81.3
rs:WP_028733673	DNA topoisomerase I [Rhizobium leguminosarum].	24.83	439	267	15	47	452	230	638	6e-13	81.3
tr:A0A0A6L9A5_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KHC70204.1};	26.11	337	202	10	56	378	275	578	7e-13	80.9
rs:WP_042467105	DNA topoisomerase I [Aeromonas salmonicida].	25.00	420	257	15	49	452	259	636	7e-13	81.3
rs:WP_030342635	DNA topoisomerase I [Streptomyces sp. NRRL S-1022].	26.74	288	172	9	77	354	299	557	7e-13	81.3
rs:WP_012829725	DNA topoisomerase I [Haliangium ochraceum].	25.23	432	262	14	44	452	360	753	7e-13	81.3
rs:WP_007219031	DNA topoisomerase III [Bacteroides cellulosilyticus].	25.07	379	241	11	18	385	216	562	7e-13	80.9
rs:WP_028946757	DNA topoisomerase I [Synechocystis sp. PCC 6714].	24.42	344	220	8	41	376	249	560	7e-13	81.3
rs:WP_009596063	DNA topoisomerase I [Xanthomonas translucens].	29.57	301	166	11	66	350	254	524	7e-13	81.3
rs:WP_037900954	DNA topoisomerase I [Streptomyces sviceus].	27.30	293	164	11	77	354	299	557	7e-13	81.3
rs:WP_028918474	DNA topoisomerase I [Pseudoxanthomonas sp. J35].	30.16	305	159	13	66	350	254	524	7e-13	81.3
tr:W4TKB6_PROAA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.54	383	236	12	30	388	221	574	7e-13	81.3
rs:WP_007451903	DNA topoisomerase I [Streptomyces coelicoflavus].	26.96	293	165	11	77	354	299	557	7e-13	81.3
rs:WP_008675116	DNA topoisomerase III [Bacteroides sp. 9_1_42FAA].	25.26	380	239	12	18	385	216	562	7e-13	80.9
rs:XP_003459054	PREDICTED: DNA topoisomerase 3-beta-1 isoformX1 [Oreochromis niloticus].	22.45	441	262	15	40	453	261	648	7e-13	81.3
rs:WP_002928190	DNA topoisomerase I [Campylobacter jejuni].	24.88	426	248	17	47	450	225	600	7e-13	81.3
rs:WP_036857354	DNA topoisomerase I, partial [Prevotella amnii].	27.86	201	127	5	74	271	276	461	7e-13	80.5
rs:WP_024857897	DNA topoisomerase I [Ruminococcus albus].	24.08	436	264	15	41	452	219	611	7e-13	81.3
rs:WP_012542049	topoisomerase I [Klebsiella pneumoniae].	26.23	385	223	14	77	446	284	622	7e-13	81.3
sp:TOP1_XYLFA	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	26.91	379	216	16	66	413	254	602	7e-13	81.3
rs:WP_024493786	DNA topoisomerase I [Streptomyces sp. AW19M42].	26.96	293	165	11	77	354	301	559	7e-13	81.3
tr:A0A0A6K2P4_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KHC55676.1};	26.11	337	202	10	56	378	275	578	7e-13	80.9
rs:WP_021139069	DNA topoisomerase I subunit omega [Aeromonas salmonicida].	25.00	420	257	15	49	452	259	636	7e-13	81.3
rs:WP_038896310	DNA topoisomerase I [Vibrio owensii].	25.65	386	223	13	77	446	291	628	7e-13	81.3
rs:WP_035012822	DNA topoisomerase I [Catenovulum agarivorans].	25.45	385	228	14	77	446	288	628	7e-13	81.3
rs:WP_014070501	topoisomerase I [Enterobacter asburiae].	27.05	281	168	8	77	354	284	530	7e-13	81.3
rs:WP_030867797	DNA topoisomerase I [Streptomyces violaceoruber].	26.96	293	165	11	77	354	299	557	7e-13	81.3
rs:XP_004868855	PREDICTED: DNA topoisomerase 3-alpha [Heterocephalus glaber].	26.34	372	207	13	112	455	285	617	7e-13	81.3
rs:XP_723146	likely DNA topoisomerase III [Candida albicans SC5314].	26.11	337	202	10	56	378	275	578	7e-13	80.9
rs:WP_037441137	DNA topoisomerase I [Pedobacter antarcticus].	24.76	319	199	8	36	352	219	498	7e-13	81.3
rs:WP_009707099	MULTISPECIES: topoisomerase I [Vibrio].	25.65	386	223	13	77	446	291	628	7e-13	81.3
rs:WP_013188968	DNA topoisomerase I [Mobiluncus curtisii].	28.01	307	174	11	70	356	286	565	7e-13	81.3
rs:WP_004850155	MULTISPECIES: topoisomerase I [Klebsiella].	25.72	381	230	14	77	446	284	622	7e-13	81.3
rs:WP_001390153	DNA topoisomerase I [Escherichia coli].	25.80	376	236	12	77	446	284	622	7e-13	81.3
rs:WP_032598760	DNA topoisomerase I [Bacteroides fragilis].	25.07	379	241	11	18	385	216	562	7e-13	80.9
tr:B5HVG2_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.30	293	164	11	77	354	312	570	7e-13	81.3
rs:WP_040190181	DNA topoisomerase I [Leuconostoc citreum].	23.77	446	258	18	36	452	235	627	7e-13	81.3
rs:WP_045819603	DNA topoisomerase I [Teredinibacter sp. 1162T.S.0a.05].	25.49	412	242	16	62	452	276	643	7e-13	81.3
rs:WP_023033786	MULTISPECIES: DNA topoisomerase I [Propionibacterium].	25.07	383	233	13	30	388	238	590	7e-13	81.3
rs:WP_029919888	DNA topoisomerase I [Nevskia soli].	27.81	338	195	12	61	379	248	555	7e-13	81.3
rs:WP_008807785	MULTISPECIES: topoisomerase I [Enterobacteriaceae].	26.23	385	223	14	77	446	284	622	7e-13	81.3
rs:WP_040007276	hypothetical protein, partial [Fibrisoma limi].	26.60	312	189	9	41	346	215	492	7e-13	80.9
rs:WP_029470217	DNA topoisomerase I [Clostridiales bacterium VE202-06].	23.53	425	273	11	48	457	227	614	7e-13	81.3
tr:A0A0A3CE31_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGQ92393.1};	26.11	337	202	10	56	378	275	578	7e-13	80.9
tr:A0A0A6J0T3_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KHC42614.1};	26.11	337	202	10	56	378	275	578	7e-13	80.9
rs:WP_048223614	DNA topoisomerase I [Enterobacter cloacae].	25.79	380	231	14	77	446	284	622	7e-13	81.3
rs:WP_039969181	DNA topoisomerase I [Veillonella dispar].	23.65	427	263	14	47	454	295	677	7e-13	81.3
rs:WP_014775458	DNA topoisomerase I [Alistipes finegoldii].	24.92	301	182	7	47	339	221	485	7e-13	81.3
tr:A0A0A4C665_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGU31296.1};	26.11	337	202	10	56	378	275	578	7e-13	80.9
rs:WP_039841572	DNA topoisomerase I [Vibrio owensii].	25.65	386	223	13	77	446	291	628	7e-13	81.3
rs:WP_023444285	hypothetical protein [Pseudomonas chloritidismutans].	26.52	396	230	16	70	446	240	593	7e-13	80.9
rs:WP_011647269	MULTISPECIES: DNA topoisomerase I [Hyphomonas].	24.45	409	250	12	70	452	254	629	7e-13	81.3
rs:WP_007287285	DNA topoisomerase I [Intestinibacter bartlettii].	23.39	419	252	14	59	454	236	608	7e-13	80.9
rs:WP_020392876	DNA topoisomerase I [Kribbella catacumbae].	29.01	293	159	14	77	354	283	541	7e-13	81.3
rs:WP_039204962	DNA topoisomerase I [Aphanizomenon flos-aquae].	25.47	424	253	16	40	443	241	621	7e-13	81.3
rs:WP_014411681	DNA topoisomerase 1 [Rickettsia prowazekii].	24.46	413	249	16	65	449	250	627	7e-13	81.3
tr:A0A061JG33_9RICK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.84	432	273	12	43	449	228	628	7e-13	81.3
rs:WP_030726803	DNA topoisomerase I [Streptomyces sp. NRRL S-237].	26.62	293	166	11	77	354	298	556	7e-13	81.3
tr:V8AUH0_9LACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.20	437	277	13	34	452	239	630	7e-13	81.3
rs:WP_038205444	DNA topoisomerase I [Vibrio tubiashii].	26.27	335	192	11	69	385	276	573	7e-13	81.3
rs:WP_015202460	DNA topoisomerase I [Crinalium epipsammum].	25.83	360	208	12	47	391	244	559	7e-13	81.3
rs:WP_004899760	DNA topoisomerase I [Leuconostoc citreum].	23.77	446	258	18	36	452	235	627	7e-13	80.9
rs:WP_003975392	MULTISPECIES: DNA topoisomerase I [Streptomyces].	26.96	293	165	11	77	354	299	557	7e-13	81.3
sp:TOP1_STRCO	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	26.96	293	165	11	77	354	299	557	7e-13	81.3
rs:WP_031046484	DNA topoisomerase I [Streptomyces sp. NRRL WC-3774].	27.30	293	164	11	77	354	299	557	7e-13	81.3
rs:WP_039266524	DNA topoisomerase I [Enterobacter sp. FB].	25.79	380	231	14	77	446	284	622	7e-13	81.3
rs:WP_025247671	DNA topoisomerase I [Mannheimia varigena].	26.39	379	230	15	77	446	290	628	7e-13	81.3
rs:XP_003493773	PREDICTED: DNA topoisomerase 3-beta-1 [Bombus impatiens].	24.58	358	226	12	37	385	258	580	7e-13	81.3
rs:WP_031367907	DNA topoisomerase I, partial [Clostridium botulinum].	24.08	407	235	16	74	454	252	610	7e-13	80.9
tr:A0A023DYM8_9RICK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.84	432	273	12	43	449	228	628	7e-13	81.3
rs:WP_017258991	DNA topoisomerase I [Pedobacter arcticus].	27.11	273	162	7	70	335	242	484	7e-13	81.3
rs:WP_033219326	DNA topoisomerase I [Streptomyces virginiae].	26.62	293	166	11	77	354	298	556	7e-13	81.3
gp:CP011125_5547	DNA topoisomerase I [Sandaracinus amylolyticus]	24.93	337	202	12	41	358	249	553	7e-13	81.3
rs:WP_044163783	DNA topoisomerase I [Bacteroides reticulotermitis].	23.80	332	218	9	61	385	263	566	7e-13	80.9
rs:WP_039483662	DNA topoisomerase I [Vibrio sinaloensis].	26.78	407	227	17	62	446	270	627	7e-13	81.3
rs:WP_015705739	topoisomerase I [Enterobacter aerogenes].	25.66	378	234	14	77	446	284	622	7e-13	81.3
rs:WP_021240303	MULTISPECIES: topoisomerase I [Enterobacter].	25.79	380	231	14	77	446	284	622	7e-13	81.3
rs:WP_023292242	MULTISPECIES: DNA topoisomerase 1 [Enterobacter cloacae complex].	25.79	380	231	14	77	446	284	622	7e-13	81.3
rs:WP_018121110	DNA topoisomerase I [Corynebacterium propinquum].	25.74	338	202	10	30	354	244	545	7e-13	81.3
rs:XP_011638711	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha [Pogonomyrmex barbatus].	23.62	436	267	14	40	449	308	703	7e-13	81.3
rs:WP_045563060	DNA topoisomerase I [Streptomyces sp. FxanaA7].	27.08	288	171	9	77	354	299	557	7e-13	81.3
rs:WP_025342644	DNA topoisomerase I [Mannheimia varigena].	26.39	379	230	15	77	446	290	628	7e-13	81.3
tr:A0A0A6LXN2_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KHC78647.1};	26.11	337	202	10	56	378	275	578	7e-13	80.9
rs:WP_042543808	DNA topoisomerase I [Leucobacter komagatae].	27.93	333	191	13	42	356	271	572	7e-13	81.3
rs:WP_018958827	DNA topoisomerase I [Streptomyces sp. CNB091].	26.55	290	170	10	77	354	301	559	7e-13	81.3
rs:WP_004007690	DNA topoisomerase I [Mobiluncus curtisii].	28.01	307	174	11	70	356	286	565	7e-13	81.3
tr:I0RMA2_MYCXE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.30	328	200	9	41	354	249	545	7e-13	81.3
tr:A0A0D0ITE6_9MICO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.93	333	191	13	42	356	257	558	8e-13	81.3
tr:A1U7T2_MARHV	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:ABM21051.1}; EC=5.99.1.2 {ECO:0000313|EMBL:ABM21051.1};	26.46	393	213	16	76	440	249	593	8e-13	80.9
rs:WP_046910172	DNA topoisomerase I [Streptomyces showdoensis].	25.29	340	198	12	37	354	252	557	8e-13	81.3
rs:WP_036138397	DNA topoisomerase I [Luteibacter sp. 9135].	27.35	362	210	15	66	405	254	584	8e-13	81.3
rs:WP_026770357	DNA topoisomerase I [Sediminibacterium sp. OR53].	25.97	308	189	9	36	339	214	486	8e-13	81.3
rs:WP_030392675	MULTISPECIES: DNA topoisomerase I [Streptomycetaceae].	26.53	294	165	12	77	354	301	559	8e-13	81.3
rs:WP_036543456	DNA topoisomerase I [Nocardioides sp. UNC345MFTsu5.1].	25.64	351	214	12	42	377	255	573	8e-13	81.3
tr:A0A0A2J5C9_PENEN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.68	342	194	8	41	359	261	558	8e-13	80.9
rs:WP_042061362	DNA topoisomerase I [Aeromonas allosaccharophila].	25.00	420	257	15	49	452	259	636	8e-13	81.3
rs:WP_032782336	DNA topoisomerase I [Streptomyces sp. JS01].	26.90	290	169	10	77	354	301	559	8e-13	81.3
rs:WP_045135520	DNA topoisomerase I [Enterobacter cloacae].	27.05	281	168	8	77	354	284	530	8e-13	81.3
rs:WP_030972245	DNA topoisomerase I [Streptomyces sp. NRRL S-1824].	26.96	293	165	11	77	354	301	559	8e-13	81.3
rs:XP_003459055	PREDICTED: DNA topoisomerase 3-beta-1 isoformX2 [Oreochromis niloticus].	22.45	441	262	15	40	453	263	650	8e-13	81.3
rs:WP_038855449	DNA topoisomerase I [Campylobacter coli].	25.00	432	252	17	41	450	219	600	8e-13	80.9
rs:WP_004011329	DNA topoisomerase I [Mobiluncus curtisii].	28.01	307	174	11	70	356	286	565	8e-13	81.3
rs:WP_009874718	topoisomerase I [Actinobacillus pleuropneumoniae].	25.06	411	255	16	47	446	261	629	8e-13	81.3
rs:WP_007174734	DNA topoisomerase I [Prevotella bergensis].	26.69	356	214	12	27	377	204	517	8e-13	80.9
tr:A0A0A3C6T3_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGQ88087.1};	26.11	337	202	10	56	378	275	578	8e-13	80.9
rs:WP_031552313	DNA topoisomerase I [Gemella sanguinis].	23.56	433	251	15	47	452	225	604	8e-13	80.9
rs:WP_045908888	DNA topoisomerase I [Enterobacter cloacae].	25.79	380	231	14	77	446	284	622	8e-13	81.3
rs:WP_020853025	hypothetical protein [Xylella fastidiosa].	45.95	74	40	0	260	333	1	74	8e-13	75.1
rs:WP_027547207	DNA topoisomerase I [Bradyrhizobium sp. WSM2254].	23.91	414	252	13	70	452	253	634	8e-13	81.3
rs:WP_039890612	DNA topoisomerase I [Mycobacterium xenopi].	25.30	328	200	9	41	354	268	564	8e-13	81.3
gp:AF099909_1	topoisomerase III [Drosophila melanogaster]	25.00	376	227	16	37	394	256	594	8e-13	81.3
rs:WP_044476138	DNA topoisomerase I, partial [Rhodococcus sp. EsD8].	25.99	327	200	9	41	354	17	314	8e-13	80.9
rs:WP_042163747	DNA topoisomerase I [Streptomyces sp. NBRC 110035].	26.96	293	165	11	77	354	299	557	8e-13	81.3
rs:WP_034915106	DNA topoisomerase I [Erwinia sp. 9145].	25.88	452	268	21	19	452	231	633	8e-13	81.3
rs:WP_032825418	topoisomerase I, partial [Oenococcus oeni].	34.72	144	84	4	224	365	1	136	8e-13	76.3
rs:WP_025217263	DNA topoisomerase I [Mannheimia varigena].	26.39	379	230	15	77	446	290	628	8e-13	81.3
rs:WP_011734472	DNA topoisomerase I [Pelobacter propionicus].	25.10	506	254	17	43	459	228	697	8e-13	80.9
rs:WP_040469686	DNA topoisomerase I [Lactobacillus ingluviei].	24.65	434	260	20	40	452	237	624	8e-13	80.9
rs:WP_031369395	DNA topoisomerase I, partial [Clostridium botulinum].	24.08	407	235	16	74	454	252	610	8e-13	80.9
rs:WP_048029764	MULTISPECIES: DNA topoisomerase I [Leclercia].	25.79	380	231	14	77	446	284	622	8e-13	81.3
rs:WP_004904017	DNA topoisomerase I [Leuconostoc citreum].	23.09	446	261	16	36	452	235	627	8e-13	80.9
rs:WP_007516566	DNA topoisomerase I [Frankia sp. CN3].	27.97	354	202	13	77	415	352	667	8e-13	81.3
rs:WP_042658666	DNA topoisomerase I [Aeromonas allosaccharophila].	25.00	420	257	15	49	452	259	636	8e-13	80.9
tr:A0A073I7K6_9PORP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.77	331	213	8	61	385	262	562	8e-13	80.9
tr:W7QXB4_9ALTE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.45	385	228	14	77	446	235	575	8e-13	80.9
rs:WP_046916528	DNA topoisomerase I [Streptomyces stelliscabiei].	26.96	293	165	11	77	354	299	557	8e-13	81.3
rs:WP_009209696	DNA topoisomerase I [Aurantimonas manganoxydans].	25.95	447	255	16	47	452	230	641	8e-13	81.3
rs:WP_005362158	MULTISPECIES: topoisomerase I [Aeromonas].	24.76	420	258	15	49	452	259	636	8e-13	80.9
rs:WP_030718342	DNA topoisomerase I [Streptomyces griseus].	26.90	290	169	10	77	354	301	559	8e-13	81.3
rs:WP_047365954	DNA topoisomerase I [Enterobacter sp. GN03191].	27.05	281	168	8	77	354	284	530	8e-13	80.9
rs:WP_022911217	DNA topoisomerase I [Aestuariimicrobium kwangyangense].	25.87	375	218	14	35	379	237	581	8e-13	81.3
rs:WP_018596075	DNA topoisomerase I [Blautia producta].	23.53	425	273	11	48	457	227	614	8e-13	80.9
sp:TOP3B_DROME	RecName: Full=DNA topoisomerase 3-beta; EC=5.99.1.2; AltName: Full=DNA topoisomerase III beta;	25.00	376	227	16	37	394	256	594	8e-13	80.9
rs:WP_002809711	DNA topoisomerase I [Campylobacter coli].	25.00	432	252	17	41	450	219	600	8e-13	80.9
rs:WP_048487809	DNA topoisomerase I, partial [Lactobacillus rhamnosus].	25.59	297	178	10	166	452	64	327	8e-13	79.3
tr:I2GTY1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.60	312	189	9	41	346	213	490	8e-13	80.9
rs:WP_035594534	DNA topoisomerase I [Hyphomonas polymorpha].	24.83	431	267	12	47	452	231	629	8e-13	80.9
rs:WP_033071499	DNA topoisomerase I [Pectobacterium wasabiae].	25.95	393	247	13	61	446	268	623	8e-13	80.9
rs:WP_015506487	DNA topoisomerase I/SWI domain fusion protein [Chlamydia trachomatis].	23.46	422	264	13	47	449	241	622	8e-13	80.9
rs:WP_019959258	DNA topoisomerase I [Vitreoscilla stercoraria].	26.44	435	255	15	41	452	225	617	8e-13	80.9
tr:Q8GE07_HELMO	RecName: Full=DNA topoisomerase I, plasmid {ECO:0000256|SAAS:SAAS00003555}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	26.03	315	184	10	28	328	213	492	8e-13	80.5
rs:WP_022076044	DNA topoisomerase [Firmicutes bacterium CAG:212].	24.38	402	246	12	74	457	266	627	8e-13	80.9
tr:W4UVJ6_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.80	332	218	9	61	385	273	576	8e-13	80.5
rs:WP_024061638	DNA topoisomerase [Veillonella dispar].	22.77	426	268	11	47	454	295	677	8e-13	80.9
rs:WP_044300295	DNA topoisomerase I [Bacteroides fragilis].	26.69	266	151	8	77	334	253	482	8e-13	80.9
rs:WP_003587235	DNA topoisomerase I [Rhizobium leguminosarum].	25.57	442	260	17	47	452	230	638	8e-13	80.9
rs:WP_048329914	DNA topoisomerase I, partial [Klebsiella pneumoniae].	26.23	385	223	14	77	446	284	622	8e-13	80.9
rs:WP_002877023	DNA topoisomerase I [Campylobacter jejuni].	24.88	426	248	17	47	450	225	600	8e-13	80.9
rs:WP_039100590	DNA topoisomerase I [Kocuria rhizophila].	26.74	344	191	14	42	356	267	578	8e-13	80.9
rs:WP_019311104	DNA topoisomerase I [Kocuria rhizophila].	26.74	344	191	14	42	356	267	578	8e-13	80.9
rs:WP_040226445	DNA topoisomerase I [Klebsiella pneumoniae].	26.63	383	224	15	77	446	284	622	9e-13	80.9
rs:WP_038676167	DNA topoisomerase I [Pimelobacter simplex].	26.76	355	205	13	42	377	255	573	9e-13	80.9
rs:WP_042217744	DNA topoisomerase I [Lactococcus garvieae].	22.20	437	277	13	34	452	239	630	9e-13	80.9
tr:A0A090RLB9_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.76	340	197	12	62	385	153	456	9e-13	80.9
rs:WP_019972782	DNA topoisomerase I [Mycobacterium sp. 141].	27.09	347	198	11	77	399	307	622	9e-13	80.9
rs:WP_036213490	DNA topoisomerase I [Lysobacter arseniciresistens].	26.41	390	231	14	50	413	238	597	9e-13	80.9
rs:XP_006410336	hypothetical protein EUTSA_v10016222mg [Eutrema salsugineum].	24.21	318	199	10	40	351	272	553	9e-13	80.9
rs:WP_030635107	DNA topoisomerase I [Streptomyces rimosus].	25.62	324	200	10	42	354	266	559	9e-13	80.9
rs:WP_023757500	DNA topoisomerase I [Mesorhizobium sp. LNHC252B00].	25.78	450	258	20	41	452	224	635	9e-13	80.9
rs:XP_002792973	DNA topoisomerase [Paracoccidioides sp. 'lutzii' Pb01].	25.87	317	181	9	73	369	294	576	9e-13	80.5
rs:WP_020593538	hypothetical protein [Kiloniella laminariae].	24.58	419	258	13	65	454	250	639	9e-13	80.9
rs:WP_033064059	DNA topoisomerase I [Clostridium botulinum].	24.08	407	235	16	74	454	252	610	9e-13	80.9
rs:WP_003712564	hypothetical protein, partial [Lactobacillus oris].	34.27	143	91	2	257	397	7	148	9e-13	77.8
rs:WP_021229836	topoisomerase I [Aeromonas veronii].	24.76	420	258	15	49	452	259	636	9e-13	80.9
rs:WP_024708367	DNA topoisomerase I [Martelella sp. AD-3].	24.54	436	258	16	54	452	237	638	9e-13	80.9
rs:XP_003852710	DNA topoisomerase 3 [Zymoseptoria tritici IPO323].	22.80	386	238	13	18	377	238	589	9e-13	80.5
rs:WP_000681440	DNA topoisomerase I [Helicobacter pylori].	25.32	395	231	16	74	450	251	599	9e-13	80.9
rs:WP_015730472	topoisomerase I [Pectobacterium wasabiae].	25.95	393	247	13	61	446	268	623	9e-13	80.9
rs:WP_014699936	DNA topoisomerase [Pectobacterium sp. SCC3193].	25.95	393	247	13	61	446	268	623	9e-13	80.9
sp:TOP3A_ARATH	RecName: Full=DNA topoisomerase 3-alpha; EC=5.99.1.2;	23.62	470	283	14	18	451	243	672	9e-13	80.9
rs:WP_032739665	DNA topoisomerase I, partial [Klebsiella pneumoniae].	26.23	385	223	14	77	446	167	505	9e-13	80.9
rs:WP_041657431	DNA topoisomerase I, partial [Marinobacter hydrocarbonoclasticus].	28.38	296	157	12	76	354	249	506	9e-13	80.5
rs:WP_025919080	DNA topoisomerase I [Pectobacterium wasabiae].	25.95	393	247	13	61	446	268	623	9e-13	80.9
rs:WP_019614490	topoisomerase I [Psychromonas ossibalaenae].	26.75	385	222	17	77	446	292	631	9e-13	80.9
rs:WP_045279509	DNA topoisomerase I [Microbacterium oxydans].	27.81	320	176	11	51	356	268	546	9e-13	80.9
rs:WP_034923839	DNA topoisomerase I [Erysipelotrichaceae bacterium NK3D112].	24.46	417	244	15	60	452	237	606	9e-13	80.9
rs:WP_041909639	MULTISPECIES: DNA topoisomerase I [Enterobacter].	27.05	281	168	8	77	354	284	530	9e-13	80.9
rs:WP_023330550	MULTISPECIES: DNA topoisomerase 1 [Enterobacter].	27.05	281	168	8	77	354	284	530	9e-13	80.9
rs:WP_014884091	MULTISPECIES: topoisomerase I [Enterobacter].	27.05	281	168	8	77	354	284	530	9e-13	80.9
rs:WP_042652626	DNA topoisomerase I [Aeromonas encheleia].	24.29	420	260	14	49	452	259	636	9e-13	80.9
rs:WP_030483292	DNA topoisomerase I [Marmoricola aequoreus].	25.85	325	197	11	42	354	257	549	9e-13	80.9
rs:WP_009644989	DNA topoisomerase I [Selenomonas sp. CM52].	25.63	437	245	18	49	457	335	719	9e-13	80.9
sp:TOP1_SYNY3	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.49	343	219	8	36	370	244	554	9e-13	80.9
rs:WP_007237854	DNA topoisomerase I [Gordonia otitidis].	25.73	342	200	11	35	351	252	564	9e-13	80.9
rs:WP_010262215	DNA topoisomerase I [Alistipes timonensis].	25.08	303	193	6	40	339	214	485	9e-13	80.9
rs:WP_004440643	DNA topoisomerase I [Clostridium botulinum].	24.08	407	235	16	74	454	252	610	9e-13	80.9
rs:XP_002036798	GM12581 [Drosophila sechellia].	25.00	376	227	16	37	394	302	640	9e-13	80.9
rs:WP_030240907	DNA topoisomerase I [Streptomyces sp. NRRL S-350].	26.53	294	165	12	77	354	301	559	9e-13	80.9
tr:A0A099P2L0_ISSOR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.59	383	211	14	37	391	203	539	9e-13	80.5
rs:WP_005811721	DNA topoisomerase I [Bacteroides fragilis].	26.69	266	151	8	77	334	253	482	9e-13	80.9
rs:WP_040017644	DNA topoisomerase I [Enterobacter ludwigii].	25.79	380	231	14	77	446	284	622	9e-13	80.9
rs:WP_045281238	DNA topoisomerase I [Enterobacter sp. 44593].	27.05	281	168	8	77	354	284	530	9e-13	80.9
rs:WP_022635683	DNA topoisomerase I [Chitinivibrio alkaliphilus].	22.75	501	288	15	18	451	187	655	9e-13	80.9
rs:WP_042082558	DNA topoisomerase I [Aeromonas veronii].	25.26	392	235	15	77	452	287	636	9e-13	80.9
rs:WP_018514247	DNA topoisomerase I [Streptomyces sp. ScaeMP-e10].	26.90	290	169	10	77	354	301	559	9e-13	80.9
rs:WP_010981336	TraB protein [uncultured bacterium].	26.67	405	238	14	70	459	252	612	9e-13	80.9
rs:XP_012922474	PREDICTED: DNA topoisomerase 3-alpha [Heterocephalus glaber].	26.34	372	207	13	112	455	259	591	9e-13	80.9
rs:WP_015232833	DNA topoisomerase I, archaeal [Caldisphaera lagunensis].	25.80	376	223	14	64	424	280	614	9e-13	80.9
tr:B4E3G2_HUMAN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.34	243	147	6	61	294	14	233	9e-13	78.2
rs:WP_045630538	DNA topoisomerase I [Enterobacter cloacae].	27.05	281	168	8	77	354	284	530	9e-13	80.9
rs:WP_044927185	DNA topoisomerase I, partial [Roseburia inulinivorans].	24.30	428	266	13	48	457	227	614	9e-13	80.9
rs:WP_031012614	DNA topoisomerase I [Streptomyces sp. NRRL WC-3773].	26.99	289	170	10	77	354	301	559	9e-13	80.9
rs:WP_014046845	MULTISPECIES: DNA topoisomerase I [Streptomyces].	26.62	293	166	11	77	354	301	559	9e-13	80.9
rs:WP_003470405	DNA topoisomerase I [Xanthomonas translucens].	29.57	301	166	11	66	350	254	524	9e-13	80.9
rs:XP_011276511	DNA topoisomerase III [Wickerhamomyces ciferrii].	26.40	356	215	11	38	378	255	578	9e-13	80.5
rs:WP_002908846	DNA topoisomerase I [Campylobacter jejuni].	25.12	426	247	17	47	450	225	600	9e-13	80.9
rs:WP_045443510	MULTISPECIES: DNA topoisomerase I [Citrobacter].	26.88	320	190	10	77	386	284	569	9e-13	80.9
rs:WP_023867727	DNA topoisomerase I [Mycobacterium avium].	25.13	394	235	12	35	399	257	619	9e-13	80.9
rs:WP_033174869	DNA topoisomerase I [Streptomyces sp. URHA0041].	26.55	290	170	11	77	354	306	564	9e-13	80.9
rs:WP_023253166	DNA topoisomerase III, partial [Salmonella enterica].	43.68	87	47	2	104	190	2	86	9e-13	74.7
rs:WP_047177953	DNA topoisomerase I [Streptomyces sp. MNU77].	26.90	290	169	10	77	354	301	559	9e-13	80.9
rs:WP_033310216	DNA topoisomerase I [Streptomyces iakyrus].	25.44	342	199	12	35	354	250	557	9e-13	80.9
rs:WP_028865557	DNA topoisomerase I [Psychromonas aquimarina].	26.87	387	219	16	77	446	292	631	9e-13	80.9
rs:XP_008879533	hypothetical protein H310_13695 [Aphanomyces invadans].	24.47	376	224	11	37	394	263	596	9e-13	80.9
rs:WP_032536933	MULTISPECIES: DNA topoisomerase I [Bacteroides].	26.69	266	151	8	77	334	253	482	9e-13	80.9
rs:WP_005781823	DNA topoisomerase I [Bacteroides fragilis].	26.69	266	151	8	77	334	253	482	9e-13	80.9
rs:WP_015122729	DNA topoisomerase I [Rivularia sp. PCC 7116].	25.86	321	197	9	77	387	291	580	9e-13	80.9
tr:W4UH72_PROAA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.80	383	234	13	30	388	238	590	9e-13	80.9
rs:WP_033572549	DNA topoisomerase I [Bacteroides sp. UW].	24.77	331	213	8	61	385	262	562	9e-13	80.5
rs:WP_044598192	DNA topoisomerase I [Campylobacter peloridis].	25.56	399	225	18	74	450	252	600	9e-13	80.5
rs:WP_036373819	DNA topoisomerase I [Mitsuokella jalaludinii].	24.38	447	270	18	36	457	251	654	9e-13	80.9
rs:WP_038831465	DNA topoisomerase I [Campylobacter coli].	24.77	432	253	17	41	450	219	600	1e-12	80.5
rs:XP_006279975	hypothetical protein CARUB_v10025845mg [Capsella rubella].	23.14	471	284	15	18	451	243	672	1e-12	80.9
rs:WP_044374707	DNA topoisomerase I [Streptomyces griseus].	26.90	290	169	10	77	354	301	559	1e-12	80.9
rs:WP_030813093	DNA topoisomerase I [Streptomyces mediolani].	26.90	290	169	10	77	354	301	559	1e-12	80.9
rs:WP_006453789	DNA topoisomerase I [Synechococcus sp. PCC 7335].	26.98	315	185	10	77	379	288	569	1e-12	80.9
rs:WP_020540892	DNA topoisomerase I [Nonomuraea coxensis].	27.93	358	201	16	31	374	264	578	1e-12	80.9
rs:XP_002106294	GD16199 [Drosophila simulans].	25.00	376	227	16	37	394	202	540	1e-12	80.9
rs:WP_044543432	DNA topoisomerase I [Mycobacterium avium].	25.13	394	235	12	35	399	257	619	1e-12	80.9
rs:WP_011087871	DNA topoisomerase I [Bradyrhizobium diazoefficiens].	23.46	439	273	13	45	452	228	634	1e-12	80.9
rs:WP_004928211	DNA topoisomerase I [Streptomyces griseoflavus].	26.96	293	165	11	77	354	299	557	1e-12	80.9
rs:XP_010673315	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Beta vulgaris subsp. vulgaris].	25.50	298	176	10	61	351	279	537	1e-12	80.9
rs:XP_005949421	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X3 [Haplochromis burtoni].	22.74	409	245	13	40	421	208	572	1e-12	80.5
rs:WP_032640977	DNA topoisomerase I [Enterobacter cloacae].	25.79	380	231	14	77	446	284	622	1e-12	80.9
rs:WP_005790119	MULTISPECIES: DNA topoisomerase III [Bacteroides].	24.47	380	242	12	18	385	216	562	1e-12	80.5
rs:WP_027460080	DNA topoisomerase I [Deinococcus murrayi].	27.64	322	184	13	40	344	250	539	1e-12	80.9
tr:E2BS26_HARSA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.35	423	240	14	60	449	278	653	1e-12	80.9
rs:WP_024460340	DNA topoisomerase I [Marinimicrobium sp. LS-A18].	24.53	424	266	13	42	452	260	642	1e-12	80.9
rs:WP_017972909	DNA topoisomerase I [Actinopolyspora halophila].	24.12	398	251	11	35	411	268	635	1e-12	80.9
rs:WP_002512962	DNA topoisomerase I [Propionibacterium acnes].	24.80	383	234	13	30	388	238	590	1e-12	80.9
rs:WP_029547225	DNA topoisomerase I [Rhodococcus sp. BCP1].	25.53	329	199	9	41	354	265	562	1e-12	80.9
rs:WP_003480796	DNA topoisomerase I [Xanthomonas translucens].	29.57	301	166	11	66	350	254	524	1e-12	80.9
rs:WP_012305122	DNA topoisomerase I [Leuconostoc citreum].	23.52	438	269	16	36	452	235	627	1e-12	80.5
tr:A0A0C6FZX7_STRPY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.40	377	213	15	98	452	1	327	1e-12	79.7
rs:XP_005949420	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X2 [Haplochromis burtoni].	22.74	409	245	13	40	421	252	616	1e-12	80.5
rs:WP_002547495	DNA topoisomerase I [Propionibacterium acnes].	24.80	383	234	13	30	388	238	590	1e-12	80.9
rs:XP_002595626	hypothetical protein BRAFLDRAFT_64736, partial [Branchiostoma floridae].	25.54	368	206	15	110	450	1	327	1e-12	80.5
rs:WP_033713039	MULTISPECIES: DNA topoisomerase I [Mycobacterium avium complex (MAC)].	25.13	394	235	12	35	399	257	619	1e-12	80.9
rs:WP_002847138	DNA topoisomerase I [Ruminococcus albus].	24.07	432	261	14	45	452	223	611	1e-12	80.5
rs:WP_019135904	DNA topoisomerase I [Cellulomonas massiliensis].	27.70	343	204	12	31	356	241	556	1e-12	80.9
tr:A0A015P4D9_BACFG	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EXY29744.1}; Flags: Fragment;	29.89	184	123	5	215	396	3	182	1e-12	78.2
gp:CP011341_608	DNA topoisomerase I [Rhodococcus aetherivorans]	25.53	329	199	9	41	354	265	562	1e-12	80.9
rs:XP_006572532	PREDICTED: DNA topoisomerase 3-like, partial [Apis mellifera].	26.30	327	186	11	69	377	117	406	1e-12	80.1
tr:A0A078GXW6_BRANA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.52	469	280	16	18	451	244	673	1e-12	80.9
rs:WP_040881631	DNA topoisomerase I, partial [Janibacter hoylei].	27.30	348	195	12	25	350	230	541	1e-12	80.9
rs:WP_039040523	MULTISPECIES: DNA topoisomerase I [Aeromonas].	24.86	346	216	9	49	384	259	570	1e-12	80.9
rs:WP_022488428	DNA topoisomerase [Clostridium sp. CAG:914].	23.47	473	290	15	1	450	172	595	1e-12	80.5
rs:WP_025796828	DNA topoisomerase I [Prevotella saccharolytica].	25.27	273	146	8	77	334	252	481	1e-12	80.5
rs:WP_028430727	DNA topoisomerase I [Streptomyces sp. TAA204].	24.39	328	199	11	42	354	266	559	1e-12	80.9
rs:WP_010705324	DNA topoisomerase I [Bartonella vinsonii].	26.19	443	254	18	47	452	230	636	1e-12	80.9
rs:WP_015391419	DNA topoisomerase 1 [Clostridium saccharoperbutylacetonicum].	22.09	430	270	13	46	454	223	608	1e-12	80.5
rs:WP_042867454	DNA topoisomerase I [Aeromonas piscicola].	25.51	392	234	15	77	452	287	636	1e-12	80.9
rs:WP_032782100	DNA topoisomerase I [Streptomyces albus].	26.90	290	169	10	77	354	301	559	1e-12	80.9
rs:WP_005470465	topoisomerase I [Vibrio sp. 16].	27.60	308	166	10	62	354	270	535	1e-12	80.9
rs:WP_043464656	DNA topoisomerase I [Streptomyces fradiae].	26.62	293	166	11	77	354	301	559	1e-12	80.9
rs:WP_032769233	DNA topoisomerase I [Streptomyces sp. CNS654].	26.90	290	169	10	77	354	301	559	1e-12	80.9
rs:WP_014544362	topoisomerase I [Erwinia sp. Ejp617].	27.04	392	228	17	77	452	284	633	1e-12	80.9
rs:WP_039666460	DNA topoisomerase I [Campylobacter sp. RM16704].	25.45	393	227	16	77	450	255	600	1e-12	80.5
rs:XP_010673316	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Beta vulgaris subsp. vulgaris].	25.50	298	176	10	61	351	220	478	1e-12	80.5
rs:WP_009010972	DNA topoisomerase I [Prevotella sp. C561].	26.87	268	154	7	77	334	252	487	1e-12	80.5
rs:WP_019707577	DNA topoisomerase I [Streptomyces xinghaiensis].	26.62	293	166	11	77	354	301	559	1e-12	80.9
tr:X7YHI8_MYCKA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.46	378	230	12	41	399	217	565	1e-12	80.9
rs:WP_000681461	DNA topoisomerase I [Helicobacter pylori].	25.19	393	234	14	74	450	251	599	1e-12	80.5
rs:WP_004952687	DNA topoisomerase I [Streptomyces mobaraensis].	26.62	293	166	11	77	354	301	559	1e-12	80.9
rs:WP_005171670	DNA topoisomerase I [Gordonia aichiensis].	25.90	332	192	11	41	351	266	564	1e-12	80.9
rs:WP_010056058	DNA topoisomerase I [Streptomyces globisporus].	26.90	290	169	10	77	354	301	559	1e-12	80.9
rs:WP_025153127	DNA topoisomerase I [Morganella morganii].	25.77	388	238	14	77	452	281	630	1e-12	80.9
rs:WP_029685549	DNA topoisomerase I [Tatumella saanichensis].	25.83	391	234	14	77	452	284	633	1e-12	80.9
rs:WP_030897702	DNA topoisomerase I [Streptomyces sp. NRRL S-474].	25.44	342	199	12	35	354	250	557	1e-12	80.9
rs:WP_042015614	DNA topoisomerase I [Aeromonas caviae].	24.86	346	216	9	49	384	259	570	1e-12	80.9
gpu:CP011799_2456	DNA topoisomerase I [Streptomyces sp. PBH53]	26.39	288	173	9	77	354	299	557	1e-12	80.9
rs:WP_011986801	DNA topoisomerase I [Clostridium botulinum].	24.08	407	235	16	74	454	256	614	1e-12	80.5
tr:A0A090QNN5_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.12	379	230	15	77	446	290	627	1e-12	80.9
rs:WP_036060875	DNA topoisomerase I [Leuconostoc citreum].	23.52	438	269	16	36	452	232	624	1e-12	80.5
rs:WP_015399038	DNA topoisomerase I [Bartonella vinsonii].	26.19	443	254	18	47	452	230	636	1e-12	80.9
rs:WP_027313742	DNA topoisomerase I [Balneatrix alpica].	24.49	392	244	13	65	446	281	630	1e-12	80.9
tr:A0A0E9AXR9_CHLTH	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CRH26064.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRH26064.1};	23.45	435	261	17	41	449	21	409	1e-12	80.5
rs:WP_041344248	DNA topoisomerase I [Mycobacterium avium].	25.13	394	235	12	35	399	257	619	1e-12	80.9
rs:WP_025643059	DNA topoisomerase I [Clostridiales bacterium VE202-26].	23.67	414	263	11	60	457	239	615	1e-12	80.5
rs:WP_045320820	DNA topoisomerase I [Streptomyces sp. NRRL F-4428].	26.62	293	166	11	77	354	298	556	1e-12	80.9
rs:WP_010888015	DNA topoisomerase I [Deinococcus radiodurans].	26.63	323	189	10	40	344	297	589	1e-12	80.9
rs:WP_006282731	DNA topoisomerase I [Prevotella bryantii].	26.77	310	187	9	30	334	207	481	1e-12	80.5
rs:WP_030029965	DNA topoisomerase I [Streptomyces flavotricini].	26.62	293	166	11	77	354	298	556	1e-12	80.9
rs:WP_032539136	DNA topoisomerase I [Bacteroides fragilis].	26.69	266	151	8	77	334	253	482	1e-12	80.5
rs:WP_047875145	DNA topoisomerase I [Photobacterium aphoticum].	26.12	379	230	15	77	446	290	627	1e-12	80.9
rs:WP_016532151	DNA topoisomerase I subunit omega, partial [Klebsiella pneumoniae].	28.57	287	160	12	77	356	284	532	1e-12	80.1
rs:WP_015140537	DNA topoisomerase I [Nostoc sp. PCC 7524].	23.70	422	263	12	40	445	241	619	1e-12	80.5
rs:WP_010936459	DNA topoisomerase I [Dehalococcoides mccartyi].	21.60	449	257	12	65	450	245	661	1e-12	80.5
rs:WP_039139011	DNA topoisomerase I [Gallibacterium anatis].	25.60	375	238	12	77	446	290	628	1e-12	80.5
rs:WP_023741453	DNA topoisomerase I [Mesorhizobium sp. LNJC395A00].	25.11	446	258	18	45	452	228	635	1e-12	80.5
rs:WP_031147671	DNA topoisomerase I [Streptomyces erythrochromogenes].	26.62	293	166	11	77	354	298	556	1e-12	80.9
rs:WP_039031854	DNA topoisomerase I [Leclercia adecarboxylata].	26.05	380	230	14	77	446	283	621	1e-12	80.5
rs:WP_033720225	DNA topoisomerase I [Mycobacterium avium].	25.13	394	235	12	35	399	257	619	1e-12	80.9
rs:WP_016495870	topoisomerase I [Enterobacter sp. R4-368].	26.32	380	229	15	77	446	284	622	1e-12	80.5
tr:A0A0A8GV49_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.45	393	227	16	77	450	254	599	1e-12	80.5
rs:WP_035738111	DNA topoisomerase I [Glycomyces arizonensis].	27.73	321	191	9	42	351	255	545	1e-12	80.9
rs:WP_012047858	DNA topoisomerase I [Clostridium botulinum].	24.08	407	235	16	74	454	252	610	1e-12	80.5
rs:XP_003351627	TOP3 protein [Sordaria macrospora k-hell].	26.88	279	160	8	65	336	229	470	1e-12	80.5
rs:XP_008879534	hypothetical protein, variant [Aphanomyces invadans].	24.47	376	224	11	37	394	263	596	1e-12	80.5
rs:WP_032080259	DNA topoisomerase I [Vibrio fluvialis].	26.30	346	191	12	62	385	273	576	1e-12	80.5
rs:WP_002542335	DNA topoisomerase I [Propionibacterium acnes].	25.00	384	228	14	35	388	237	590	1e-12	80.9
rs:WP_009974717	DNA topoisomerase I [Mycobacterium avium].	25.13	394	235	12	35	399	257	619	1e-12	80.9
rs:WP_017457189	topoisomerase I [Kosakonia sacchari].	26.32	380	229	15	77	446	284	622	1e-12	80.5
rs:WP_047348265	DNA topoisomerase I [Enterobacter sp. GN03164].	25.79	380	231	14	77	446	284	622	1e-12	80.5
rs:WP_035375720	DNA topoisomerase I, partial [Acholeplasma axanthum].	26.30	403	235	14	66	452	237	593	1e-12	80.1
rs:WP_038138899	DNA topoisomerase I [Vibrio caribbeanicus].	27.60	308	166	10	62	354	270	535	1e-12	80.5
rs:WP_025756584	MULTISPECIES: DNA topoisomerase I [Enterobacter].	25.79	380	231	14	77	446	284	622	1e-12	80.5
rs:WP_023175222	DNA topoisomerase I [Gloeobacter kilaueensis].	25.23	428	262	13	40	447	236	625	1e-12	80.5
tr:A0A0A9Y6R2_LYGHE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.09	357	222	12	40	385	263	581	1e-12	80.5
rs:WP_046507750	DNA topoisomerase I [Kiloniella sp. P1-1].	24.88	418	254	14	65	452	250	637	1e-12	80.5
rs:WP_039478450	DNA topoisomerase I [Vibrio sinaloensis].	27.60	308	166	10	62	354	270	535	1e-12	80.5
rs:WP_007166600	DNA topoisomerase I [Mycobacterium parascrofulaceum].	25.00	380	233	11	41	399	271	619	1e-12	80.5
rs:WP_003877079	DNA topoisomerase I [Mycobacterium avium].	25.13	394	235	12	35	399	257	619	1e-12	80.5
rs:WP_033725396	DNA topoisomerase I [Mycobacterium avium].	25.13	394	235	12	35	399	257	619	1e-12	80.5
rs:WP_009872013	DNA topoisomerase I [Chlamydia trachomatis].	23.36	428	257	16	47	449	241	622	1e-12	80.5
rs:WP_037933747	DNA topoisomerase I [Streptomyces toyocaensis].	26.96	293	165	11	77	354	299	557	1e-12	80.5
rs:WP_034813314	DNA topoisomerase I [Hyphomonas sp. L-53-1-40].	24.41	422	262	12	57	452	239	629	1e-12	80.5
rs:WP_038212929	DNA topoisomerase I [Vibrio variabilis].	27.60	308	166	10	62	354	270	535	1e-12	80.5
rs:WP_038192898	DNA topoisomerase I [Vibrio sinaloensis].	27.60	308	166	10	62	354	270	535	1e-12	80.5
rs:WP_031085642	DNA topoisomerase I [Streptomyces sp. NRRL S-1831].	26.96	293	165	11	77	354	299	557	1e-12	80.5
rs:WP_031482315	DNA topoisomerase I [Desulfovibrio frigidus].	24.47	421	256	13	47	450	225	600	1e-12	80.5
rs:WP_010633259	MULTISPECIES: DNA topoisomerase I subunit omega [Aeromonas].	24.29	420	260	14	49	452	259	636	1e-12	80.5
rs:WP_025403727	DNA topoisomerase I [Corynebacterium falsenii].	26.01	323	188	10	47	356	301	585	1e-12	80.9
rs:WP_035472386	DNA topoisomerase I [Alistipes sp. 627].	28.73	268	154	8	77	340	246	480	1e-12	80.5
rs:WP_019705470	topoisomerase I [Klebsiella pneumoniae].	26.84	380	227	15	77	446	284	622	1e-12	80.5
rs:WP_026303763	DNA topoisomerase I [Gordonia kroppenstedtii].	25.21	353	206	11	35	362	248	567	1e-12	80.5
rs:WP_038289162	DNA topoisomerase I [[Clostridium] straminisolvens].	26.00	400	237	12	77	457	256	615	1e-12	80.5
rs:WP_013989151	DNA topoisomerase I [Weissella koreensis].	23.60	445	266	15	34	452	229	625	1e-12	80.5
rs:WP_030046534	DNA topoisomerase I [Streptomyces peruviensis].	25.44	342	199	12	35	354	250	557	1e-12	80.5
rs:WP_018250099	hypothetical protein [Orenia marismortui].	24.49	445	255	20	40	456	224	615	1e-12	80.5
rs:WP_045821525	DNA topoisomerase I [Williamsia sp. ARP1].	24.92	329	201	9	41	354	266	563	1e-12	80.9
rs:WP_015840249	topoisomerase I [Pectobacterium carotovorum].	25.31	399	242	13	61	446	268	623	1e-12	80.5
rs:WP_012361083	DNA topoisomerase I [Corynebacterium urealyticum].	24.93	357	221	10	41	378	258	586	1e-12	80.5
rs:WP_037735554	DNA topoisomerase I [Streptomyces mirabilis].	26.62	293	166	11	77	354	299	557	1e-12	80.5
rs:XP_003694833	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha [Apis florea].	23.15	445	266	13	37	449	1058	1458	1e-12	80.9
rs:WP_000681460	DNA topoisomerase I [Helicobacter pylori].	26.01	396	227	17	74	450	251	599	1e-12	80.5
rs:WP_000681398	DNA topoisomerase I [Helicobacter pylori].	24.43	397	232	15	74	450	251	599	1e-12	80.5
rs:WP_039634246	DNA topoisomerase I [Streptomyces sp. 769].	27.68	289	168	10	77	354	301	559	1e-12	80.5
rs:XP_001978430	GG17682 [Drosophila erecta].	23.67	376	232	13	37	394	256	594	1e-12	80.5
rs:WP_046777872	DNA topoisomerase I [Streptomyces sp. fd2-tb].	26.62	293	166	11	77	354	298	556	1e-12	80.5
rs:XP_005949419	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X1 [Haplochromis burtoni].	22.74	409	245	13	40	421	261	625	1e-12	80.5
tr:H2WE23_CAEJA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.07	335	203	10	53	377	275	571	1e-12	80.5
rs:WP_034406896	DNA topoisomerase I [Deinococcus sp. RL].	27.64	322	184	13	40	344	250	539	1e-12	80.5
rs:WP_015317636	DNA topoisomerase I [Mesorhizobium australicum].	25.39	449	261	18	41	452	224	635	1e-12	80.5
rs:WP_004413385	topoisomerase I [Vibrio orientalis].	25.59	340	190	11	69	386	276	574	1e-12	80.5
rs:XP_011144136	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Harpegnathos saltator].	24.35	423	240	14	60	449	293	668	1e-12	80.5
rs:WP_002863984	DNA topoisomerase I [Campylobacter jejuni].	25.06	427	246	18	47	450	225	600	1e-12	80.5
rs:WP_002823480	DNA topoisomerase I [Campylobacter coli].	25.00	432	252	17	41	450	219	600	1e-12	80.5
rs:WP_030404212	DNA topoisomerase I [Streptomyces sp. NRRL F-5555].	26.96	293	165	11	77	354	299	557	1e-12	80.5
rs:WP_018386178	DNA topoisomerase I [Streptomyces vitaminophilus].	26.61	327	193	13	42	354	266	559	1e-12	80.5
rs:WP_005607588	topoisomerase I [Actinobacillus pleuropneumoniae].	24.82	411	256	16	47	446	261	629	1e-12	80.5
rs:WP_029743490	DNA topoisomerase, partial [Enterococcus faecium].	31.61	155	97	4	93	243	19	168	1e-12	76.3
rs:WP_026635325	DNA topoisomerase I [Dyella japonica].	29.29	338	186	17	66	380	254	561	1e-12	80.5
rs:WP_045329359	DNA topoisomerase I [Enterobacter asburiae].	25.79	380	231	14	77	446	284	622	1e-12	80.5
rs:WP_011223762	DNA topoisomerase I [Haloarcula marismortui].	25.52	239	158	6	60	295	265	486	1e-12	80.9
rs:WP_019557205	DNA topoisomerase I [Thiomicrospira arctica].	26.37	292	176	8	47	335	223	478	1e-12	80.5
rs:WP_027081690	DNA topoisomerase I [Lysobacter sp. URHA0019].	27.11	380	219	16	66	417	254	603	1e-12	80.5
rs:WP_024835713	DNA topoisomerase I [Clostridium sp. 12(A)].	23.89	427	268	12	48	457	230	616	1e-12	80.5
rs:WP_030795887	DNA topoisomerase I [Streptomyces sp. NRRL F-5008].	25.27	364	217	13	77	422	299	625	1e-12	80.5
rs:WP_044306347	DNA topoisomerase I [Campylobacter jejuni].	24.88	426	248	17	47	450	225	600	1e-12	80.5
rs:WP_043521232	MULTISPECIES: DNA topoisomerase I [Enterobacteriaceae].	26.04	384	225	15	77	446	284	622	1e-12	80.5
rs:WP_015407675	DNA topoisomerase I [Dehalococcoides mccartyi].	21.33	483	283	13	33	450	211	661	1e-12	80.5
tr:E9IAV6_SOLIN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.77	426	248	12	60	451	278	656	1e-12	80.5
rs:WP_027398235	DNA topoisomerase I [Anaerovorax odorimutans].	21.83	458	272	13	47	453	231	653	1e-12	80.5
rs:WP_034738529	DNA topoisomerase I [Hyphomonas chukchiensis].	23.61	432	271	12	47	452	231	629	1e-12	80.5
rs:WP_018241618	DNA topoisomerase I [Rhizobium leguminosarum].	24.60	439	268	15	47	452	230	638	1e-12	80.5
rs:NP_220161	DNA topoisomerase I [Chlamydia trachomatis D/UW-3/CX].	23.36	428	257	16	47	449	241	622	1e-12	80.5
rs:WP_046839141	DNA topoisomerase I [Candidatus Synechococcus spongiarum].	25.35	359	234	8	40	393	249	578	1e-12	80.5
rs:WP_004957538	DNA topoisomerase I [Haloarcula sinaiiensis].	25.52	239	158	6	60	295	265	486	1e-12	80.9
rs:WP_036881443	DNA topoisomerase I [Porphyromonas sp. COT-239 OH1446].	25.07	347	215	8	2	334	168	483	1e-12	80.5
rs:WP_017161855	hypothetical protein, partial [Xanthomonas axonopodis].	47.50	80	42	0	30	109	237	316	1e-12	78.6
rs:WP_033161459	DNA topoisomerase I [Mycoplasma collis].	25.00	388	207	16	89	450	273	602	1e-12	80.1
tr:K1Y6Q8_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.74	392	233	16	77	452	264	609	1e-12	80.5
rs:XP_011144135	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Harpegnathos saltator].	24.35	423	240	14	60	449	325	700	1e-12	80.5
tr:A0A0B8NKQ9_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.37	339	204	11	35	356	243	549	1e-12	80.5
rs:WP_017030334	topoisomerase I [Vibrio breoganii].	25.32	387	223	13	77	446	290	627	1e-12	80.5
rs:WP_031184668	DNA topoisomerase I [Streptomyces sp. NRRL F-5635].	26.96	293	165	11	77	354	299	557	1e-12	80.5
rs:XP_010673317	PREDICTED: DNA topoisomerase 3-beta isoform X3 [Beta vulgaris subsp. vulgaris].	25.50	298	176	10	61	351	196	454	1e-12	80.5
rs:WP_000681416	DNA topoisomerase I [Helicobacter pylori].	25.25	396	230	17	74	450	251	599	1e-12	80.5
rs:WP_041093558	DNA topoisomerase I [Lactobacillus hokkaidonensis].	24.43	438	254	21	41	452	239	625	1e-12	80.5
rs:WP_028700909	DNA topoisomerase I [Propionibacterium acidipropionici].	23.64	368	223	11	36	379	251	584	1e-12	80.5
rs:WP_022452649	DNA topoisomerase [Prevotella sp. CAG:873].	28.33	300	177	7	40	334	243	509	1e-12	80.5
rs:WP_040578076	DNA topoisomerase I, partial [Methylophilales bacterium HTCC2181].	26.23	408	241	18	65	452	252	619	1e-12	80.5
rs:WP_046445616	DNA topoisomerase I [Alistipes sp. N15.MGS-157].	28.73	268	154	8	77	340	265	499	1e-12	80.5
tr:A0A0A0NL09_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.09	345	192	14	26	354	262	559	1e-12	80.5
tr:V6M7K9_9EUKA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.18	426	251	14	37	434	248	629	1e-12	80.5
rs:WP_005872450	DNA topoisomerase I [Actinomyces georgiae].	27.41	332	192	11	77	385	289	594	1e-12	80.5
rs:WP_039044872	DNA topoisomerase I [Plesiomonas shigelloides].	25.51	396	245	17	61	446	273	628	1e-12	80.5
tr:A0P4J6_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.23	408	241	18	65	452	252	619	1e-12	80.5
rs:WP_030957759	DNA topoisomerase I [Streptomyces sp. NRRL S-378].	26.62	293	166	11	77	354	298	556	1e-12	80.5
rs:WP_029345828	DNA topoisomerase I [Lactococcus garvieae].	22.65	437	275	13	34	452	239	630	1e-12	80.5
rs:WP_030907881	DNA topoisomerase I [Streptomyces sp. NRRL S-384].	26.53	294	165	12	77	354	300	558	1e-12	80.5
rs:WP_041949576	hypothetical protein [Turneriella parva].	24.19	430	240	15	63	446	241	630	1e-12	80.5
rs:WP_034973169	DNA topoisomerase I [Epilithonimonas lactis].	27.36	329	175	12	36	349	217	496	1e-12	80.5
rs:WP_036405715	DNA topoisomerase I [Mycobacterium kansasii].	26.46	378	230	12	41	399	283	631	1e-12	80.5
rs:WP_019446731	topoisomerase I [Aeromonas sp. 159].	24.29	420	260	14	49	452	259	636	1e-12	80.5
rs:WP_020974013	DNA topoisomerase I [Campylobacter coli].	24.77	432	253	17	41	450	219	600	1e-12	80.1
rs:WP_009237164	DNA topoisomerase I [Prevotella sp. oral taxon 472].	26.18	317	184	12	47	358	232	503	1e-12	80.5
rs:WP_018966719	DNA topoisomerase I [Prevotella loescheii].	26.18	317	184	12	47	358	232	503	1e-12	80.5
tr:G4NN22_CHLT4	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.36	428	257	16	47	449	254	635	1e-12	80.5
tr:I4BAN4_TURPD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.19	430	240	15	63	446	262	651	1e-12	80.5
rs:WP_012594201	DNA topoisomerase I [Cyanothece sp. PCC 8801].	24.86	346	225	9	41	379	249	566	1e-12	80.5
rs:WP_020882439	MULTISPECIES: DNA topoisomerase I [Enterobacter].	25.79	380	231	14	77	446	284	622	1e-12	80.5
rs:WP_007187672	DNA topoisomerase I [Haloarcula californiae].	25.52	239	158	6	60	295	265	486	1e-12	80.5
rs:WP_023828664	DNA topoisomerase I [Mesorhizobium sp. L103C120A0].	25.11	446	258	18	45	452	228	635	1e-12	80.5
rs:WP_038688242	DNA topoisomerase I [Rhizobium etli].	25.06	439	266	15	47	452	230	638	1e-12	80.5
rs:WP_023738966	MULTISPECIES: DNA topoisomerase I [Mesorhizobium].	25.11	446	258	18	45	452	228	635	1e-12	80.5
rs:WP_001938164	DNA topoisomerase I [Helicobacter pylori].	25.19	397	229	16	74	450	251	599	1e-12	80.1
rs:WP_022012244	DNA topoisomerase [Bacteroides fragilis CAG:558].	25.76	264	156	7	77	334	253	482	1e-12	80.5
rs:WP_032611192	DNA topoisomerase I [Leclercia adecarboxylata].	26.05	380	230	14	77	446	283	621	1e-12	80.5
rs:WP_022032109	DNA topoisomerase [Clostridium hathewayi CAG:224].	24.30	428	265	11	48	457	230	616	1e-12	80.1
rs:WP_025714303	DNA topoisomerase I [Klebsiella sp. 10982].	26.09	391	216	15	77	446	284	622	1e-12	80.5
rs:WP_008799769	DNA topoisomerase III [Fusobacterium nucleatum].	21.91	429	273	13	40	445	249	638	1e-12	80.5
rs:WP_047616568	MULTISPECIES: DNA topoisomerase I [Rhizobium].	24.83	439	267	15	47	452	230	638	1e-12	80.5
rs:WP_031041790	DNA topoisomerase I [Streptomyces sp. NRRL F-5650].	26.96	293	165	11	77	354	299	557	1e-12	80.5
rs:WP_028325750	DNA topoisomerase I [Desulfatirhabdium butyrativorans].	25.55	411	242	17	65	452	244	613	1e-12	80.5
rs:WP_043298255	DNA topoisomerase I, partial [Burkholderia sp. TSV202].	25.93	405	241	15	70	459	252	612	1e-12	80.5
rs:WP_030981908	DNA topoisomerase I [Streptomyces sp. NRRL WC-3744].	26.96	293	165	11	77	354	299	557	1e-12	80.5
tr:A0A061B4A7_CYBFA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.00	372	220	12	40	397	278	604	1e-12	80.1
rs:WP_038528814	DNA topoisomerase I, partial [Weissella ceti].	23.04	421	247	12	58	452	260	629	1e-12	80.1
rs:WP_040234733	DNA topoisomerase I, partial [Klebsiella pneumoniae].	28.57	287	160	12	77	356	284	532	1e-12	80.1
rs:WP_020250963	MULTISPECIES: hypothetical protein [unclassified Cloacimonetes].	23.76	425	250	16	47	452	235	604	1e-12	80.1
rs:WP_005208330	DNA topoisomerase I [Gordonia sputi].	24.88	426	249	15	35	424	252	642	1e-12	80.5
rs:WP_034962999	DNA topoisomerase I [Epilithonimonas sp. FH1].	27.36	329	175	12	36	349	217	496	1e-12	80.5
rs:WP_026063933	DNA topoisomerase I [Lactococcus garvieae].	22.20	437	277	13	34	452	239	630	1e-12	80.1
rs:WP_030863305	DNA topoisomerase I [Streptomyces sp. NRRL S-37].	26.96	293	165	11	77	354	311	569	1e-12	80.5
rs:WP_030412618	DNA topoisomerase I [Streptomyces sp. NRRL S-1448].	27.68	289	168	10	77	354	301	559	1e-12	80.5
rs:WP_018321114	DNA topoisomerase I [Bradyrhizobium sp. WSM2793].	24.29	424	258	12	60	452	243	634	1e-12	80.5
rs:WP_013681861	DNA topoisomerase I [Hippea maritima].	24.19	401	232	12	77	454	255	606	1e-12	80.1
tr:G0NRK3_CAEBE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.00	350	208	13	40	377	261	571	1e-12	80.1
rs:WP_022089219	DNA topoisomerase [Eubacterium sp. CAG:156].	22.99	435	263	13	48	457	227	614	1e-12	80.1
rs:WP_020851581	DNA topoisomerase I [Xylella fastidiosa].	26.53	392	227	16	53	413	241	602	1e-12	80.5
rs:WP_012487618	topoisomerase I [Cellvibrio japonicus].	25.53	427	258	16	42	452	260	642	1e-12	80.5
rs:WP_015900135	DNA topoisomerase I [Staphylococcus carnosus].	24.18	397	236	15	77	452	254	606	1e-12	80.1
rs:WP_041572324	DNA topoisomerase I, partial [Xylella fastidiosa].	26.28	392	228	16	53	413	241	602	1e-12	80.1
rs:WP_044278325	hypothetical protein [Campylobacter jejuni].	33.16	187	101	7	288	458	3	181	1e-12	77.4
rs:WP_017963880	DNA topoisomerase I [Rhizobium leguminosarum].	24.60	439	268	15	47	452	230	638	1e-12	80.5
rs:XP_008860486	DNA topoisomerase domain containing protein [Entamoeba nuttalli P19].	24.27	375	235	12	30	384	241	586	1e-12	80.5
gp:CP002165_604	DNA topoisomerase I [Xylella fastidiosa subsp. fastidiosa GB514]	26.28	392	228	16	53	413	241	602	1e-12	80.5
rs:WP_021687743	DNA topoisomerase I [Treponema lecithinolyticum].	24.06	424	256	17	50	452	240	618	1e-12	80.1
rs:WP_009538494	DNA topoisomerase I [Caenispirillum salinarum].	24.31	432	249	17	61	454	244	635	1e-12	80.5
rs:WP_019329839	MULTISPECIES: DNA topoisomerase I [Streptomyces].	27.08	288	171	9	77	354	299	557	1e-12	80.5
rs:WP_019002142	hypothetical protein [Succinimonas amylolytica].	24.77	327	197	9	38	354	235	522	1e-12	80.5
tr:S5SRZ9_9CORY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.52	363	219	11	41	386	253	577	1e-12	80.5
rs:XP_006797644	PREDICTED: DNA topoisomerase 3-beta-1-like [Neolamprologus brichardi].	22.45	441	262	15	40	453	261	648	1e-12	80.5
rs:WP_025271724	DNA topoisomerase [Streptococcus anginosus].	23.84	344	226	10	59	397	263	575	1e-12	80.1
rs:WP_000681413	DNA topoisomerase I [Helicobacter pylori].	26.01	396	227	18	74	450	251	599	1e-12	80.1
rs:WP_018625461	topoisomerase I [Kangiella aquimarina].	24.06	345	216	11	51	384	270	579	1e-12	80.5
rs:WP_032104631	DNA topoisomerase I, partial [Klebsiella pneumoniae].	28.57	287	160	12	77	356	284	532	1e-12	80.1
rs:WP_046249243	DNA topoisomerase I [Streptomyces sp. MBT28].	27.08	288	171	9	77	354	299	557	1e-12	80.5
tr:C7IPE3_THEET	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.06	303	173	12	166	454	69	337	1e-12	79.3
rs:WP_011782535	MULTISPECIES: DNA topoisomerase I [Mycobacterium].	25.15	338	198	10	41	354	277	583	1e-12	80.5
rs:WP_045012346	DNA topoisomerase I [Bradyrhizobium sp. LTSP849].	24.15	414	251	13	70	452	253	634	1e-12	80.5
rs:WP_032999419	DNA topoisomerase I, partial [Mesorhizobium sp. LNJC405B00].	25.11	446	258	18	45	452	228	635	1e-12	80.5
rs:WP_012170389	DNA topoisomerase I [Azorhizobium caulinodans].	25.83	422	240	15	69	454	253	637	1e-12	80.5
rs:XP_011119958	hypothetical protein AOL_s00054g340 [Arthrobotrys oligospora ATCC 24927].	27.27	297	160	8	48	334	276	526	1e-12	80.1
tr:G8LDT2_ENTCL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.79	380	231	14	77	446	286	624	1e-12	80.5
rs:WP_048426354	DNA topoisomerase I [Methylobacterium platani].	26.26	457	232	19	43	452	236	634	1e-12	80.5
rs:WP_040098544	DNA topoisomerase I [Aeromonas australiensis].	24.52	420	259	15	49	452	259	636	1e-12	80.5
rs:WP_030651338	MULTISPECIES: DNA topoisomerase I [Streptomyces].	26.96	293	165	11	77	354	299	557	1e-12	80.5
rs:WP_003644423	DNA topoisomerase I [Lactobacillus plantarum].	23.82	403	237	16	77	457	283	637	1e-12	80.1
rs:WP_022264915	DNA topoisomerase [Clostridium sp. CAG:352].	23.75	459	259	18	47	449	236	659	1e-12	80.1
rs:WP_045740525	DNA topoisomerase I [Actinoplanes rectilineatus].	25.97	385	234	14	42	409	261	611	1e-12	80.5
tr:F1ZA60_9SPHN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.03	411	236	16	69	452	246	615	1e-12	80.5
rs:WP_044779754	DNA topoisomerase I [Campylobacter jejuni].	24.54	432	254	17	41	450	219	600	1e-12	80.1
rs:WP_018075375	DNA topoisomerase I [Novosphingobium nitrogenifigens].	26.03	411	236	16	69	452	251	620	1e-12	80.5
rs:WP_031072374	DNA topoisomerase I [Streptomyces sp. NRRL WC-3742].	26.19	294	166	12	77	354	301	559	1e-12	80.5
rs:WP_026230854	DNA topoisomerase I [Rhizobium gallicum].	24.60	439	268	15	47	452	230	638	1e-12	80.5
rs:WP_047622599	DNA topoisomerase I [Rhizobium leguminosarum].	24.60	439	268	15	47	452	230	638	1e-12	80.5
rs:WP_038966363	DNA topoisomerase I [Bradyrhizobium sp. CCBAU 41267].	23.64	423	260	13	61	452	244	634	1e-12	80.5
rs:WP_039425546	DNA topoisomerase I [Porphyromonas gulae].	27.42	299	165	9	47	338	228	481	1e-12	80.1
rs:WP_031123959	DNA topoisomerase I [Streptomyces sp. NRRL S-623].	26.55	290	170	10	77	354	301	559	1e-12	80.5
rs:WP_022046703	GTP-sensing transcriptional pleiotropic repressor CodY [Roseburia sp. CAG:18].	23.06	425	269	12	48	454	227	611	1e-12	80.1
rs:XP_006623297	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X1 [Apis dorsata].	24.23	355	225	12	40	385	261	580	1e-12	80.1
tr:X5Y3R3_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.11	446	258	18	45	452	228	635	1e-12	80.5
rs:WP_023704548	MULTISPECIES: DNA topoisomerase I [Mesorhizobium].	25.51	443	260	17	45	452	228	635	1e-12	80.5
rs:WP_022064027	DNA topoisomerase [Alistipes sp. CAG:157].	28.73	268	154	8	77	340	265	499	1e-12	80.1
rs:WP_002645950	DNA topoisomerase I [Gimesia maris].	23.70	346	225	8	41	377	256	571	1e-12	80.5
rs:WP_015570386	MULTISPECIES: DNA topoisomerase I [Enterobacter].	25.79	380	231	14	77	446	284	622	1e-12	80.1
rs:WP_042481986	DNA topoisomerase I [Vibrio diazotrophicus].	25.63	394	235	14	69	446	279	630	1e-12	80.1
rs:WP_046559052	DNA topoisomerase I [Arsukibacterium ikkense].	27.22	360	205	13	42	384	245	564	1e-12	80.1
rs:WP_027685122	DNA topoisomerase I [Rhizobium leguminosarum].	24.60	439	268	15	47	452	230	638	1e-12	80.1
rs:WP_031092069	MULTISPECIES: DNA topoisomerase I [Streptomyces].	26.96	293	165	11	77	354	299	557	1e-12	80.5
rs:WP_031028009	DNA topoisomerase I [Streptomyces sp. NRRL WC-3725].	26.96	293	165	11	77	354	299	557	1e-12	80.5
rs:WP_023725728	MULTISPECIES: DNA topoisomerase I [Mesorhizobium].	25.51	443	260	17	45	452	228	635	1e-12	80.1
rs:WP_042820708	DNA topoisomerase I [Streptomyces sp. RSD-27].	26.62	293	166	11	77	354	298	556	1e-12	80.5
rs:YP_001654102	DNA topoisomerase I [Chlamydia trachomatis 434/Bu].	23.36	428	257	16	47	449	241	622	1e-12	80.1
rs:WP_018390664	DNA topoisomerase I [Ancylobacter sp. FA202].	25.73	443	249	16	47	454	240	637	1e-12	80.1
rs:WP_008824364	hypothetical protein, partial [Prevotella histicola].	26.34	243	157	7	22	259	221	446	1e-12	79.3
rs:WP_039252884	DNA topoisomerase I [Clostridium novyi].	23.90	431	258	15	50	457	228	611	1e-12	80.1
rs:WP_021809457	DNA topoisomerase I [Leifsonia rubra].	25.58	344	206	13	30	356	244	554	1e-12	80.5
rs:WP_039775658	DNA topoisomerase I [Nocardia cerradoensis].	25.30	328	205	9	41	356	256	555	1e-12	80.5
rs:WP_020588848	DNA topoisomerase I [Desulfobacter curvatus].	24.94	429	255	15	47	452	225	609	1e-12	80.1
rs:WP_014558129	DNA topoisomerase III [Fervidicoccus fontis].	26.84	313	184	8	53	358	265	539	1e-12	80.1
rs:WP_023822968	DNA topoisomerase I [Mesorhizobium sp. L103C565B0].	25.11	446	258	18	45	452	228	635	1e-12	80.1
rs:WP_023714241	DNA topoisomerase I [Mesorhizobium sp. LSHC422A00].	25.11	446	258	18	45	452	228	635	1e-12	80.1
rs:WP_027467839	DNA topoisomerase I [Deefgea rivuli].	25.47	424	256	14	50	452	235	619	1e-12	80.1
rs:WP_045737421	DNA topoisomerase I [Xanthomonas sp. MUS 060].	29.24	301	167	11	66	350	254	524	1e-12	80.1
rs:WP_047955699	DNA topoisomerase I [Enterobacter cloacae].	25.79	380	231	14	77	446	284	622	1e-12	80.1
rs:WP_016533828	DNA topoisomerase I subunit omega, partial [Pasteurella multocida].	24.05	370	232	13	86	446	2	331	1e-12	79.7
rs:WP_023681566	DNA topoisomerase I [Mesorhizobium sp. LSJC277A00].	25.11	446	258	18	45	452	228	635	1e-12	80.1
rs:WP_023547745	DNA topoisomerase I [Streptomyces roseochromogenus].	26.96	293	165	11	77	354	299	557	1e-12	80.1
rs:WP_033886444	DNA topoisomerase I, partial [Bacteroides faecichinchillae].	25.16	318	195	8	36	340	201	488	1e-12	80.1
rs:WP_024295678	MULTISPECIES: DNA topoisomerase I [Lachnoclostridium].	23.65	427	269	12	48	457	230	616	1e-12	80.1
rs:WP_000681495	DNA topoisomerase I [Helicobacter pylori].	24.94	393	235	14	74	450	251	599	1e-12	80.1
rs:WP_033089386	hypothetical protein, partial [Nocardia seriolae].	25.37	339	204	11	35	356	268	574	1e-12	80.1
tr:A0A075TZU3_9LACT	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:AIM62706.1};	23.04	421	247	12	58	452	260	629	1e-12	80.1
tr:A0A0D3AYL4_BRAOL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.24	462	290	16	18	451	244	673	1e-12	80.1
rs:WP_022109119	DNA topoisomerase, partial [Clostridium sp. CAG:533].	23.69	287	153	8	208	455	7	266	1e-12	77.8
rs:WP_035552266	DNA topoisomerase I [Hyphomonas atlantica].	24.14	435	265	13	47	452	231	629	1e-12	80.1
rs:WP_044800504	DNA topoisomerase I [Aeromonas hydrophila].	24.29	420	260	14	49	452	259	636	1e-12	80.1
rs:WP_040745021	DNA topoisomerase I, partial [Nocardia transvalensis].	25.84	329	198	10	41	354	276	573	1e-12	80.1
rs:WP_025831016	DNA topoisomerase III [Bacteroides stercorirosoris].	24.74	380	241	12	18	385	216	562	1e-12	79.7
rs:WP_000681514	DNA topoisomerase I [Helicobacter pylori].	25.25	396	230	16	74	450	251	599	1e-12	80.1
rs:WP_022655238	DNA topoisomerase I [Desulfovibrio sp. Dsv1].	25.95	420	230	16	61	459	236	595	1e-12	80.1
gp:CP009154_15	DNA topoisomerase I [Burkholderia sp. TSV202]	25.93	405	241	15	70	459	252	612	1e-12	80.1
tr:W5Q119_SHEEP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.81	266	167	7	40	295	265	507	1e-12	80.1
rs:XP_009130424	PREDICTED: DNA topoisomerase 3-alpha [Brassica rapa].	24.09	469	282	16	18	451	244	673	1e-12	80.1
rs:WP_023821402	DNA topoisomerase I [Mesorhizobium sp. L2C054A000].	25.11	446	258	18	45	452	228	635	2e-12	80.1
rs:WP_005353832	topoisomerase I [Aeromonas veronii].	24.29	420	260	14	49	452	259	636	2e-12	80.1
rs:WP_023667567	DNA topoisomerase I [Mesorhizobium sp. LSJC285A00].	25.11	446	258	18	45	452	228	635	2e-12	80.1
rs:WP_033736007	DNA topoisomerase I [Helicobacter pylori].	25.19	393	234	14	74	450	251	599	2e-12	80.1
tr:I0GNA0_SELRL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.06	439	262	16	41	456	234	628	2e-12	80.1
rs:WP_024556117	DNA topoisomerase I [Cronobacter pulveris].	26.56	320	191	10	77	386	285	570	2e-12	80.1
rs:WP_005597038	topoisomerase I [Actinobacillus pleuropneumoniae].	24.82	411	256	16	47	446	261	629	2e-12	80.1
rs:WP_015609426	DNA topoisomerase I [Streptomyces fulvissimus].	26.55	290	170	10	77	354	301	559	2e-12	80.1
rs:WP_006962916	topoisomerase I [Vibrio coralliilyticus].	25.81	341	199	12	62	385	270	573	2e-12	80.1
tr:K1S3C4_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC55112.1}; Flags: Fragment;	32.03	128	80	3	56	179	107	231	2e-12	77.4
rs:WP_023710622	MULTISPECIES: DNA topoisomerase I [Mesorhizobium].	25.51	443	260	17	45	452	228	635	2e-12	80.1
rs:WP_023751519	DNA topoisomerase I [Mesorhizobium sp. LNJC380A00].	25.51	443	260	17	45	452	228	635	2e-12	80.1
rs:WP_032758714	DNA topoisomerase I [Streptomyces alboviridis].	26.55	290	170	10	77	354	301	559	2e-12	80.1
rs:WP_031509212	DNA topoisomerase I [Streptomyces megasporus].	27.30	293	164	10	77	354	304	562	2e-12	80.1
rs:WP_041631689	DNA topoisomerase I [Corynebacterium maris].	24.52	363	219	11	41	386	265	589	2e-12	80.1
rs:WP_045728597	DNA topoisomerase I [Xanthomonas sp. GPE 39].	29.24	301	167	11	66	350	254	524	2e-12	80.1
tr:W1E0K2_KLEPN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.57	287	160	12	77	356	284	532	2e-12	79.7
rs:WP_046481020	DNA topoisomerase I [Citrobacter amalonaticus].	25.79	380	231	14	77	446	284	622	2e-12	80.1
rs:WP_039619142	DNA topoisomerase I [Rhizobium etli].	25.06	439	266	15	47	452	230	638	2e-12	80.1
rs:WP_005614950	topoisomerase I [Actinobacillus pleuropneumoniae].	24.57	411	257	16	47	446	261	629	2e-12	80.1
rs:WP_015787846	DNA topoisomerase I [Saccharomonospora viridis].	26.46	325	197	10	40	351	271	566	2e-12	80.1
rs:WP_028121072	DNA topoisomerase I [Epilithonimonas tenax].	27.30	326	179	11	36	349	217	496	2e-12	80.1
rs:WP_011892291	DNA topoisomerase I [Mycobacterium gilvum].	25.93	378	226	13	55	410	282	627	2e-12	80.1
rs:WP_037921053	DNA topoisomerase I [Streptomyces sp. PCS3-D2].	26.62	293	166	11	77	354	298	556	2e-12	80.1
rs:WP_043128999	DNA topoisomerase I [Aeromonas media].	24.05	420	261	13	49	452	259	636	2e-12	80.1
rs:WP_038156048	DNA topoisomerase I [Vibrio sp. B183].	25.81	341	199	12	62	385	270	573	2e-12	80.1
rs:WP_021454958	topoisomerase I [Vibrio coralliilyticus].	25.81	341	199	12	62	385	270	573	2e-12	80.1
rs:WP_000681516	DNA topoisomerase I [Helicobacter pylori].	25.25	396	230	16	74	450	251	599	2e-12	80.1
tr:A0A0A4BKN3_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGU10324.1};	25.82	337	203	10	56	378	275	578	2e-12	79.7
rs:WP_019218588	DNA topoisomerase I [Bartonella sp. R4(2010)].	26.59	425	237	18	67	452	248	636	2e-12	80.1
rs:XP_011142892	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Harpegnathos saltator].	24.73	364	218	13	37	385	258	580	2e-12	80.1
rs:WP_040233497	DNA topoisomerase III, partial [Klebsiella pneumoniae].	29.26	188	106	6	288	459	2	178	2e-12	77.4
rs:WP_043494493	DNA topoisomerase I [Streptomyces ghanaensis].	26.96	293	165	11	77	354	299	557	2e-12	80.1
rs:WP_043008734	DNA topoisomerase I [Vibrio coralliilyticus].	25.81	341	199	12	62	385	270	573	2e-12	80.1
rs:WP_048385234	DNA topoisomerase I [Marinobacter psychrophilus].	25.75	400	244	15	59	446	276	634	2e-12	80.1
tr:T1BKU1_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EQD53929.1};	26.46	325	193	12	46	356	252	544	2e-12	80.1
gp:CP002222_1474	DNA topoisomerase I [Lactobacillus plantarum subsp. plantarum ST-III]	23.82	403	237	16	77	457	251	605	2e-12	80.1
rs:WP_004203874	MULTISPECIES: DNA topoisomerase I subunit omega [Klebsiella].	26.04	384	225	15	77	446	284	622	2e-12	80.1
rs:WP_039081779	DNA topoisomerase I [Gallibacterium anatis].	25.07	375	240	12	77	446	290	628	2e-12	80.1
rs:WP_013707568	DNA topoisomerase I [Desulfobacca acetoxidans].	26.82	440	252	19	38	452	213	607	2e-12	80.1
rs:WP_039418184	DNA topoisomerase I [Porphyromonas gulae].	27.42	299	165	9	47	338	228	481	2e-12	80.1
rs:WP_027050377	DNA topoisomerase I [Mesorhizobium sp. URHB0007].	25.11	446	258	18	45	452	228	635	2e-12	80.1
rs:WP_019277761	topoisomerase I [Vibrio coralliilyticus].	25.81	341	199	12	62	385	270	573	2e-12	80.1
rs:WP_021704046	DNA topoisomerase I [Vibrio proteolyticus].	26.43	333	194	12	69	385	278	575	2e-12	80.1
rs:WP_040176937	DNA topoisomerase I [Klebsiella pneumoniae].	26.58	380	228	15	77	446	284	622	2e-12	80.1
rs:WP_034321765	DNA topoisomerase I [Helicobacter trogontum].	22.77	426	269	13	41	450	225	606	2e-12	80.1
rs:WP_045008032	DNA topoisomerase I [Bradyrhizobium sp. LTSP857].	24.15	414	251	13	70	452	253	634	2e-12	80.1
rs:WP_025104275	DNA topoisomerase I [Microbacterium paraoxydans].	27.22	316	183	11	51	356	268	546	2e-12	80.1
rs:WP_041018111	DNA topoisomerase I [Criblamydia sequanensis].	24.05	395	245	14	77	454	275	631	2e-12	80.1
rs:WP_012263525	DNA topoisomerase I [Chlamydia trachomatis].	23.36	428	257	16	47	449	241	622	2e-12	80.1
rs:WP_015506113	DNA topoisomerase I/SWI domain fusion protein [Chlamydia trachomatis].	23.36	428	257	16	47	449	241	622	2e-12	80.1
rs:WP_016351565	DNA topoisomerase I subunit omega [Aeromonas hydrophila].	24.29	420	260	14	49	452	259	636	2e-12	80.1
rs:WP_041914241	DNA topoisomerase I [Selenomonas ruminantium].	25.06	439	262	16	41	456	241	635	2e-12	80.1
rs:WP_038151022	DNA topoisomerase I [Vibrio furnissii].	26.88	346	189	12	62	385	272	575	2e-12	80.1
rs:WP_039442045	DNA topoisomerase I [Porphyromonas gulae].	27.42	299	165	9	47	338	228	481	2e-12	80.1
rs:WP_024113581	DNA topoisomerase I [Helicobacter pylori].	25.19	393	234	14	74	450	251	599	2e-12	80.1
tr:A0A0F4GJZ0_9PEZI	SubName: Full=DNA topoisomerase III like protein {ECO:0000313|EMBL:KJX97392.1};	23.62	343	216	11	18	350	238	544	2e-12	80.1
rs:WP_015439910	DNA topoisomerase I [Ilumatobacter coccineus].	27.48	393	221	12	42	409	233	586	2e-12	80.1
rs:WP_018458334	DNA topoisomerase I [Bradyrhizobium sp. WSM4349].	23.64	423	260	13	61	452	244	634	2e-12	80.1
rs:WP_024359426	MULTISPECIES: DNA topoisomerase I [Enterobacteriaceae].	25.40	378	235	14	77	446	284	622	2e-12	80.1
rs:WP_005622925	topoisomerase I [Actinobacillus ureae].	24.82	411	256	16	47	446	261	629	2e-12	80.1
tr:G4AHU9_AGGAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.22	351	223	11	102	446	4	317	2e-12	79.7
rs:WP_014674049	DNA topoisomerase I [Streptomyces hygroscopicus].	26.96	293	165	11	77	354	299	557	2e-12	80.1
tr:A0A0D6QN89_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.42	444	262	15	49	452	273	678	2e-12	80.1
tr:A5DM60_PICGU	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EDK40263.2};	26.48	355	210	10	49	385	268	589	2e-12	79.7
rs:WP_022327068	DNA topoisomerase [Prevotella sp. CAG:732].	26.92	260	158	7	77	334	252	481	2e-12	80.1
rs:WP_026328586	DNA topoisomerase I [Streptomyces sulphureus].	25.68	292	170	10	77	354	301	559	2e-12	80.1
rs:WP_037690948	DNA topoisomerase I [Streptomyces atratus].	25.00	328	197	11	42	354	266	559	2e-12	80.1
rs:WP_011706893	DNA topoisomerase I [Aeromonas hydrophila].	24.29	420	260	14	49	452	259	636	2e-12	80.1
rs:WP_034412968	DNA topoisomerase I [Candidatus Photodesmus blepharus].	26.12	291	165	11	77	354	288	541	2e-12	80.1
rs:WP_027029180	DNA topoisomerase I [Mesorhizobium loti].	26.16	451	255	21	41	452	224	635	2e-12	80.1
rs:WP_033444032	hypothetical protein, partial [Dietzia alimentaria].	25.69	327	186	10	47	354	288	576	2e-12	80.1
rs:WP_044418591	DNA topoisomerase I [Rhodopseudomonas palustris].	25.85	441	265	13	45	454	228	637	2e-12	80.1
rs:WP_018360551	hypothetical protein [Porphyromonas macacae].	26.15	325	187	11	40	352	221	504	2e-12	80.1
rs:WP_002604312	DNA topoisomerase I [Hungatella hathewayi].	24.07	428	266	11	48	457	230	616	2e-12	79.7
rs:XP_011167166	PREDICTED: DNA topoisomerase 3-alpha [Solenopsis invicta].	22.69	432	251	13	60	455	324	708	2e-12	80.1
rs:WP_045527759	DNA topoisomerase I [Aeromonas hydrophila].	24.29	420	260	14	49	452	259	636	2e-12	80.1
rs:WP_018089992	DNA topoisomerase I [Streptomyces sp. FxanaC1].	27.43	288	170	10	77	354	317	575	2e-12	80.1
rs:XP_006394227	hypothetical protein EUTSA_v10003618mg [Eutrema salsugineum].	23.88	469	283	16	18	451	244	673	2e-12	80.1
rs:WP_048323904	DNA topoisomerase I [Klebsiella pneumoniae].	26.04	384	225	15	77	446	284	622	2e-12	80.1
rs:WP_030285364	DNA topoisomerase I [Streptomyces catenulae].	27.30	293	164	11	77	354	301	559	2e-12	80.1
rs:WP_021183094	DNA topoisomerase I [Pantoea sp. AS-PWVM4].	27.23	393	226	18	77	452	285	634	2e-12	80.1
rs:WP_007001207	DNA topoisomerase I [Actinobaculum massiliense].	26.36	349	199	12	61	384	270	585	2e-12	80.1
rs:WP_021461512	topoisomerase I [Gallibacterium anatis].	25.07	375	240	12	77	446	290	628	2e-12	80.1
rs:WP_029304161	DNA topoisomerase I [Aeromonas hydrophila].	24.29	420	260	14	49	452	259	636	2e-12	80.1
rs:WP_027480031	DNA topoisomerase I [Deinococcus radiodurans].	26.63	323	189	10	40	344	259	551	2e-12	80.1
rs:WP_017030849	topoisomerase I [Vibrio breoganii].	25.32	387	223	13	77	446	290	627	2e-12	80.1
rs:WP_024968195	DNA topoisomerase I [Pantoea sp. IMH].	25.67	448	274	19	19	452	231	633	2e-12	80.1
rs:WP_038958010	DNA topoisomerase I [Bradyrhizobium japonicum].	24.59	423	256	14	61	452	244	634	2e-12	80.1
rs:WP_025287779	DNA topoisomerase I [Helicobacter pylori].	24.94	397	234	16	74	452	251	601	2e-12	79.7
rs:WP_039096786	DNA topoisomerase I [Gallibacterium anatis].	25.07	375	240	12	77	446	290	628	2e-12	80.1
rs:WP_039791863	DNA topoisomerase III, partial [Haemophilus sputorum].	35.85	106	68	0	37	142	192	297	2e-12	77.8
tr:S9PZ31_SCHOY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.79	351	211	9	61	394	279	593	2e-12	79.7
rs:WP_043121319	DNA topoisomerase I [Aeromonas hydrophila].	24.29	420	260	14	49	452	259	636	2e-12	80.1
rs:WP_043282143	hypothetical protein, partial [Pseudonocardia sp. P2].	25.39	323	199	9	42	351	272	565	2e-12	80.1
tr:H2SPY9_TAKRU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTRUP00000014476};	22.57	443	265	15	37	453	260	650	2e-12	79.7
rs:WP_028421010	DNA topoisomerase I [Streptomyces sp. GXT6].	26.96	293	165	11	77	354	299	557	2e-12	80.1
rs:XP_011953620	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Ovis aries].	24.81	266	167	7	40	295	263	505	2e-12	79.7
tr:D6A7S0_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.96	293	165	11	77	354	312	570	2e-12	80.1
rs:WP_005280920	DNA topoisomerase I [Corynebacterium accolens].	24.93	361	214	12	47	384	266	592	2e-12	80.1
rs:WP_042078125	DNA topoisomerase I [Aeromonas sanarellii].	24.57	346	217	9	49	384	259	570	2e-12	80.1
rs:XP_002837817	hypothetical protein [Tuber melanosporum Mel28].	24.71	340	212	10	73	400	292	599	2e-12	79.7
rs:WP_022866500	DNA topoisomerase I [Actinotignum urinale].	26.35	334	197	11	40	356	248	549	2e-12	80.1
rs:WP_014870995	topoisomerase I [Marinobacter sp. BSs20148].	26.13	398	245	15	59	446	276	634	2e-12	80.1
rs:WP_039089898	DNA topoisomerase I [Gallibacterium anatis].	25.07	375	240	12	77	446	290	628	2e-12	80.1
rs:WP_015349034	DNA topoisomerase I [Myxococcus stipitatus].	22.94	449	273	13	41	452	293	705	2e-12	80.1
tr:N1ZMY9_9CLOT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.74	396	239	12	73	449	265	616	2e-12	79.7
tr:F0LSG3_VIBFN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.88	346	189	12	62	385	213	516	2e-12	80.1
rs:WP_010665160	DNA topoisomerase I [Marinilabilia salmonicolor].	26.44	261	157	7	77	334	259	487	2e-12	80.1
rs:WP_006604135	DNA topoisomerase I [Streptomyces auratus].	27.43	288	170	10	77	354	312	570	2e-12	80.1
rs:WP_007568290	DNA topoisomerase I [Bacteroides coprocola].	26.64	289	159	8	77	345	249	504	2e-12	80.1
sp:TOP1_XYLFT	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	26.28	392	228	16	53	413	241	602	2e-12	80.1
rs:WP_041216392	DNA topoisomerase I [Aeromonas hydrophila].	24.29	420	260	14	49	452	259	636	2e-12	80.1
rs:WP_035295700	DNA topoisomerase I [Clostridium sp. ASF356].	23.74	396	239	12	73	449	259	610	2e-12	79.7
rs:WP_039472168	DNA topoisomerase I [Pedobacter kyungheensis].	26.89	305	176	9	36	335	219	481	2e-12	80.1
rs:WP_015382009	DNA topoisomerase I [Corynebacterium urealyticum].	24.93	357	221	10	41	378	258	586	2e-12	80.1
rs:WP_041341774	DNA topoisomerase I [Dehalococcoides mccartyi].	21.38	449	258	12	65	450	245	661	2e-12	79.7
rs:WP_034991900	DNA topoisomerase I [Beijerinckia mobilis].	26.62	447	245	17	47	452	230	634	2e-12	80.1
rs:WP_035390023	DNA topoisomerase I [Ferrimicrobium acidiphilum].	26.59	331	186	10	47	354	260	556	2e-12	80.1
rs:WP_030122938	DNA topoisomerase I [[Kitasatospora] papulosa].	26.55	290	170	10	77	354	299	557	2e-12	80.1
rs:WP_046926801	DNA topoisomerase I [Streptomyces lydicus].	27.43	288	170	10	77	354	301	559	2e-12	80.1
rs:WP_042051062	MULTISPECIES: DNA topoisomerase I [Aeromonas].	24.29	420	260	14	49	452	259	636	2e-12	80.1
rs:WP_000681517	DNA topoisomerase I [Helicobacter pylori].	25.25	396	230	16	74	450	251	599	2e-12	79.7
rs:WP_030177274	DNA topoisomerase I [Streptomyces sp. NRRL S-813].	26.96	293	165	11	77	354	299	557	2e-12	80.1
rs:WP_030422570	DNA topoisomerase I [Streptomyces sp. NRRL F-5065].	26.96	293	165	11	77	354	299	557	2e-12	80.1
rs:WP_036000431	DNA topoisomerase I, partial [Leptolyngbya sp. JSC-1].	26.91	353	209	13	41	379	249	566	2e-12	79.7
rs:WP_023695425	MULTISPECIES: DNA topoisomerase I [Mesorhizobium].	25.11	446	258	18	45	452	228	635	2e-12	80.1
rs:WP_046039372	DNA topoisomerase I [Lactobacillus plantarum].	23.82	403	237	16	77	457	283	637	2e-12	79.7
rs:WP_034790972	DNA topoisomerase I [Ewingella americana].	24.93	381	233	13	77	446	284	622	2e-12	80.1
rs:WP_004121251	topoisomerase I [Klebsiella oxytoca].	25.40	378	235	14	77	446	284	622	2e-12	80.1
rs:WP_038936326	DNA topoisomerase I [Bradyrhizobium japonicum].	24.11	423	258	13	61	452	244	634	2e-12	80.1
rs:WP_029413081	DNA topoisomerase I [Acidobacteria bacterium JGI 0001001-H03].	26.62	308	181	9	36	340	224	489	2e-12	80.1
rs:WP_029168316	DNA topoisomerase I [alpha proteobacterium SCGC AAA023-L09].	24.83	435	270	12	50	454	233	640	2e-12	80.1
rs:WP_027177059	DNA topoisomerase I [Desulfovibrio aminophilus].	26.17	405	244	13	66	450	248	617	2e-12	80.1
rs:WP_024891862	DNA topoisomerase I [Luteimonas huabeiensis].	28.44	334	190	13	66	380	254	557	2e-12	80.1
rs:WP_024521591	DNA topoisomerase I [Lactobacillus plantarum].	23.82	403	237	16	77	457	283	637	2e-12	79.7
rs:WP_030925183	DNA topoisomerase I [Streptomyces sp. NRRL B-24720].	26.62	293	166	11	77	354	301	559	2e-12	80.1
rs:WP_023016601	MULTISPECIES: DNA topoisomerase I [Corynebacterium].	24.93	361	214	12	47	384	266	592	2e-12	80.1
rs:WP_041501630	DNA topoisomerase I [Lactobacillus heilongjiangensis].	23.24	469	289	18	18	457	191	617	2e-12	79.7
rs:WP_012242292	topoisomerase I [Acholeplasma laidlawii].	23.13	441	261	16	29	451	209	589	2e-12	79.7
rs:WP_027338680	DNA topoisomerase I [Halonatronum saccharophilum].	23.90	431	261	16	47	456	232	616	2e-12	79.7
rs:WP_030845817	DNA topoisomerase I [Streptomyces sp. NRRL F-4474].	26.62	293	166	11	77	354	298	556	2e-12	80.1
rs:WP_045352264	DNA topoisomerase I [Lactobacillus plantarum].	23.82	403	237	16	77	457	283	637	2e-12	79.7
rs:WP_039276197	DNA topoisomerase I [Pectobacterium carotovorum].	24.81	399	244	13	61	446	268	623	2e-12	80.1
rs:WP_044310449	DNA topoisomerase III, partial [Pseudomonas syringae].	42.57	101	57	1	31	130	140	240	2e-12	77.0
rs:WP_005276527	DNA topoisomerase I [Corynebacterium accolens].	24.93	361	214	12	47	384	266	592	2e-12	80.1
rs:WP_046496617	DNA topoisomerase I [Streptomyces sp. NRRL B-24891].	26.64	289	171	10	77	354	299	557	2e-12	80.1
rs:WP_024944133	DNA topoisomerase I [Aeromonas hydrophila].	24.29	420	260	14	49	452	259	636	2e-12	80.1
rs:WP_003645027	DNA topoisomerase [Lactobacillus plantarum].	23.82	403	237	16	77	457	283	637	2e-12	79.7
rs:WP_008484103	topoisomerase I [Gallaecimonas xiamenensis].	25.99	404	236	17	65	452	258	614	2e-12	80.1
rs:WP_016705620	DNA topoisomerase I [Mycobacterium avium].	25.19	389	236	11	35	399	257	614	2e-12	80.1
rs:WP_029823273	DNA topoisomerase I [Vibrio parahaemolyticus].	25.13	378	235	13	77	446	291	628	2e-12	80.1
rs:WP_014155474	MULTISPECIES: DNA topoisomerase I [Streptomyces].	27.08	288	171	10	77	354	299	557	2e-12	80.1
rs:WP_039142357	DNA topoisomerase I [Gallibacterium anatis].	25.07	375	240	12	77	446	290	628	2e-12	80.1
rs:XP_011616870	PREDICTED: probable G-protein coupled receptor 144 [Takifugu rubripes].	22.57	443	265	15	37	453	260	650	2e-12	80.1
rs:WP_039168906	DNA topoisomerase I [Gallibacterium anatis].	25.07	375	240	12	77	446	290	628	2e-12	80.1
rs:WP_030939244	DNA topoisomerase I [Streptomyces violaceoruber].	25.44	342	199	12	35	354	250	557	2e-12	80.1
rs:WP_016589524	topoisomerase I [Yersinia pestis].	24.47	380	236	13	77	446	290	628	2e-12	80.1
rs:WP_044430780	DNA topoisomerase I [Lactobacillus plantarum].	23.82	403	237	16	77	457	283	637	2e-12	79.7
rs:WP_046099430	DNA topoisomerase I [Staphylococcus carnosus].	24.56	395	237	16	77	452	254	606	2e-12	79.7
rs:XP_009765589	PREDICTED: DNA topoisomerase 3-beta isoform X3 [Nicotiana sylvestris].	23.27	434	268	16	39	453	195	582	2e-12	79.7
rs:WP_027518393	DNA topoisomerase I [Bradyrhizobium sp. WSM1417].	23.91	414	252	13	70	452	253	634	2e-12	80.1
rs:WP_013421527	DNA topoisomerase I [Frankia sp. EuI1c].	25.34	363	223	11	42	387	315	646	2e-12	80.1
rs:WP_027017461	DNA topoisomerase I [Corynebacterium pseudodiphtheriticum].	25.37	339	202	10	30	354	244	545	2e-12	80.1
rs:WP_039158618	DNA topoisomerase I [Gallibacterium anatis].	25.07	375	240	12	77	446	290	628	2e-12	79.7
rs:WP_039091086	DNA topoisomerase I [Gallibacterium anatis].	25.07	375	240	12	77	446	290	628	2e-12	79.7
rs:WP_023539660	DNA topoisomerase I [Streptomyces niveus].	26.99	289	170	10	77	354	299	557	2e-12	80.1
rs:WP_023018857	MULTISPECIES: DNA topoisomerase I [Corynebacterium].	25.37	339	202	10	30	354	244	545	2e-12	80.1
rs:WP_043160059	DNA topoisomerase I [Aeromonas hydrophila].	24.29	420	260	14	49	452	259	636	2e-12	79.7
rs:WP_033610393	DNA topoisomerase I [Lactobacillus paraplantarum].	23.82	403	237	16	77	457	283	637	2e-12	79.7
rs:WP_045770649	DNA topoisomerase I [Xanthomonas albilineans].	29.24	301	167	11	66	350	254	524	2e-12	79.7
rs:WP_011784655	MULTISPECIES: topoisomerase I [Marinobacter].	24.11	419	271	14	35	446	254	632	2e-12	79.7
rs:WP_022308153	DNA topoisomerase [Alistipes sp. CAG:268].	27.82	266	160	7	77	340	251	486	2e-12	79.7
rs:WP_010130561	topoisomerase I [Microbulbifer agarilyticus].	23.84	411	258	11	47	446	266	632	2e-12	80.1
rs:WP_027872316	DNA topoisomerase I [[Eubacterium] cellulosolvens].	25.99	404	236	15	74	457	253	613	2e-12	79.7
rs:WP_012557347	DNA topoisomerase I [Rhizobium leguminosarum].	24.83	439	267	15	47	452	230	638	2e-12	79.7
rs:WP_021731562	DNA topoisomerase I [Lactobacillus plantarum].	23.82	403	237	16	77	457	283	637	2e-12	79.7
rs:WP_042150501	DNA topoisomerase I [Streptomyces sp. NBRC 110027].	27.43	288	170	10	77	354	300	558	2e-12	80.1
rs:WP_028018800	DNA topoisomerase I [Enterobacter cloacae].	26.69	281	169	8	77	354	284	530	2e-12	79.7
rs:WP_039135930	DNA topoisomerase I [Gallibacterium genomosp. 2].	25.07	375	240	12	77	446	290	628	2e-12	79.7
rs:WP_041205259	DNA topoisomerase I [Aeromonas media].	24.52	420	259	14	49	452	259	636	2e-12	79.7
rs:WP_008688650	DNA topoisomerase I [Eubacterium sp. 3_1_31].	24.52	416	246	13	60	452	236	606	2e-12	79.7
tr:A0A0D3FE73_9ORYZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.11	423	263	14	39	435	235	625	2e-12	79.7
rs:WP_034949065	DNA topoisomerase I [Erwinia oleae].	25.88	452	268	21	19	452	231	633	2e-12	79.7
rs:WP_039420547	DNA topoisomerase I [Porphyromonas gulae].	28.25	269	151	8	77	338	248	481	2e-12	79.7
rs:XP_006623298	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X2 [Apis dorsata].	24.23	355	225	12	40	385	261	580	2e-12	79.7
tr:C6HWV0_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.60	439	258	21	47	452	274	672	2e-12	79.7
rs:WP_020252236	MULTISPECIES: hypothetical protein [unclassified Cloacimonetes].	23.71	426	249	16	47	452	235	604	2e-12	79.7
rs:WP_039145862	DNA topoisomerase I [Gallibacterium anatis].	25.07	375	240	12	77	446	290	628	2e-12	79.7
rs:XP_007247893	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Astyanax mexicanus].	24.67	381	236	12	39	412	287	623	2e-12	79.7
rs:WP_017461890	DNA topoisomerase I [Dyella ginsengisoli].	27.89	337	192	13	66	380	254	561	2e-12	79.7
rs:WP_045299384	DNA topoisomerase I [Saccharothrix sp. ST-888].	26.53	294	165	12	77	354	299	557	2e-12	79.7
rs:WP_043556342	DNA topoisomerase I [Aeromonas bestiarum].	25.24	420	256	16	49	452	259	636	2e-12	79.7
rs:WP_021671624	DNA topoisomerase I [Prevotella sp. F0091].	25.17	290	169	8	77	350	252	509	2e-12	79.7
rs:WP_020210395	topoisomerase I [Gilvimarinus chinensis].	25.70	428	255	17	43	452	261	643	2e-12	79.7
rs:WP_004859900	DNA topoisomerase I [Bartonella taylorii].	25.83	422	246	17	67	453	248	637	2e-12	79.7
rs:WP_012115886	DNA topoisomerase I [Xanthobacter autotrophicus].	27.83	442	241	19	47	454	240	637	2e-12	79.7
rs:WP_005515801	DNA topoisomerase I [Rhodococcus equi].	25.99	327	200	10	41	354	265	562	2e-12	79.7
rs:WP_026474023	DNA topoisomerase I [Alkaliflexus imshenetskii].	27.06	303	177	9	36	335	229	490	2e-12	79.7
rs:WP_018531980	DNA topoisomerase I [Streptomyces sp. HmicA12].	26.62	293	166	11	77	354	302	560	2e-12	79.7
tr:E2A6W4_CAMFO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.94	417	245	14	60	449	278	653	2e-12	80.1
rs:WP_030677905	DNA topoisomerase I [Streptomyces sp. NRRL B-1347].	26.74	288	172	9	77	354	297	555	2e-12	79.7
rs:WP_013414752	DNA topoisomerase I [Rhodococcus equi].	25.99	327	200	10	41	354	265	562	2e-12	79.7
rs:WP_030564994	DNA topoisomerase I [Streptomyces cyaneofuscatus].	26.55	290	170	10	77	354	301	559	2e-12	79.7
rs:WP_012917334	DNA topoisomerase I [Xanthomonas albilineans].	29.24	301	167	11	66	350	254	524	2e-12	79.7
rs:WP_012441352	topoisomerase I [Erwinia tasmaniensis].	26.55	388	235	16	77	452	284	633	2e-12	79.7
rs:XP_011780214	DNA topoisomerase III, putative [Trypanosoma brucei gambiense DAL972].	28.42	278	152	10	85	353	297	536	2e-12	79.7
tr:A0A0C9MTR8_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.55	334	213	7	60	387	282	582	2e-12	79.7
rs:XP_001632081	predicted protein, partial [Nematostella vectensis].	24.51	408	242	14	69	450	286	653	2e-12	79.7
rs:WP_042366602	DNA topoisomerase I [Bacteroidaceae bacterium MS4].	26.09	299	185	7	40	334	216	482	2e-12	79.7
rs:WP_030880763	DNA topoisomerase I [Streptomyces varsoviensis].	26.64	289	171	10	77	354	301	559	2e-12	79.7
rs:WP_039086764	DNA topoisomerase I [Gallibacterium anatis].	25.07	375	240	12	77	446	290	628	2e-12	79.7
rs:WP_026430828	DNA topoisomerase I [Actinomyces georgiae].	27.41	332	192	11	77	385	289	594	2e-12	79.7
rs:WP_004086454	DNA topoisomerase I [Xylella fastidiosa].	26.65	379	217	16	66	413	254	602	2e-12	79.7
rs:WP_022158785	DNA topoisomerase [Prevotella sp. CAG:520].	28.03	264	158	8	77	338	252	485	2e-12	79.7
rs:WP_012864401	DNA topoisomerase I [Veillonella parvula].	22.60	416	281	10	47	454	295	677	2e-12	79.7
rs:WP_045976753	DNA topoisomerase I [Vibrio neptunius].	25.81	341	199	12	62	385	270	573	2e-12	79.7
rs:WP_024111853	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	2e-12	79.7
rs:WP_021755795	DNA topoisomerase I [Leifsonia xyli].	28.23	372	217	13	30	380	238	580	2e-12	79.7
rs:WP_030881010	DNA topoisomerase I [Streptomyces sp. NRRL B-24051].	27.08	288	171	10	77	354	299	557	2e-12	79.7
rs:WP_022258149	DNA topoisomerase [Clostridium sp. CAG:508].	22.41	424	274	11	47	454	226	610	2e-12	79.7
rs:WP_036872829	DNA topoisomerase I [Porphyromonas macacae].	26.15	325	187	11	40	352	221	504	2e-12	79.7
rs:WP_015577732	DNA topoisomerase I [Streptomyces sp. PAMC26508].	27.08	288	171	10	77	354	299	557	2e-12	79.7
rs:WP_045766368	DNA topoisomerase I [Xanthomonas albilineans].	29.24	301	167	11	66	350	254	524	2e-12	79.7
rs:WP_025612444	DNA topoisomerase I [Vibrio parahaemolyticus].	25.26	384	227	13	77	446	291	628	2e-12	79.7
rs:WP_033587723	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	2e-12	79.7
rs:WP_046844366	DNA topoisomerase I ['Deinococcus soli' Cha et al. 2014].	26.40	322	186	10	40	344	254	541	2e-12	79.7
rs:WP_042991232	hypothetical protein, partial [Bifidobacterium adolescentis].	33.71	175	100	4	280	445	57	224	2e-12	77.4
rs:WP_009625014	DNA topoisomerase I [Pseudanabaena biceps].	23.39	449	268	18	30	446	225	629	2e-12	79.7
rs:XP_012768565	DNA topoisomerase family protein, putative [Babesia bigemina].	25.70	323	196	12	40	354	255	541	2e-12	79.3
rs:WP_004744344	topoisomerase I [Vibrio tubiashii].	25.06	395	236	15	69	446	276	627	2e-12	79.7
rs:WP_018118313	DNA topoisomerase I [Corynebacterium mastitidis].	24.62	325	208	7	41	354	266	564	2e-12	79.7
rs:WP_045508058	DNA topoisomerase I [Kosakonia oryzae].	26.32	380	229	15	77	446	284	622	2e-12	79.7
rs:WP_039166606	DNA topoisomerase I [Gallibacterium anatis].	25.07	375	240	12	77	446	290	628	2e-12	79.7
tr:A0A0E9KPI3_9HYPO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:GAO14784.1};	25.89	282	165	7	61	335	18	262	2e-12	78.6
rs:WP_021305666	DNA topoisomerase I [Helicobacter pylori].	25.32	395	231	16	74	450	251	599	2e-12	79.7
rs:WP_027530037	DNA topoisomerase I [Bradyrhizobium sp. WSM3983].	23.88	423	259	13	61	452	244	634	2e-12	79.7
rs:WP_009189847	DNA topoisomerase I [Streptomyces sp. e14].	26.96	293	165	11	77	354	299	557	2e-12	79.7
rs:WP_024105897	topoisomerase I [Dickeya dianthicola].	25.13	398	244	16	61	446	269	624	2e-12	79.7
rs:WP_042529016	DNA topoisomerase I [Corynebacterium singulare].	25.43	346	209	12	56	384	268	581	2e-12	79.7
rs:WP_038055559	hypothetical protein [Thermodesulfobacterium hydrogeniphilum].	22.91	371	231	11	1	356	169	499	2e-12	79.3
rs:WP_037164306	DNA topoisomerase I [Rhodococcus fascians].	26.92	338	196	12	35	354	261	565	2e-12	79.7
rs:WP_019662974	DNA topoisomerase I [Rhodococcus sp. 29MFTsu3.1].	26.92	338	196	12	35	354	261	565	2e-12	79.7
rs:WP_033190107	DNA topoisomerase I [Rhodococcus fascians].	26.92	338	196	12	35	354	261	565	2e-12	79.7
tr:A0A0C1HCF0_9CHLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.60	428	269	13	43	452	249	636	2e-12	79.7
rs:WP_031482602	DNA topoisomerase I [Streptomyces bicolor].	26.96	293	165	11	77	354	299	557	2e-12	79.7
rs:WP_014730265	DNA topoisomerase I [Mesotoga prima].	25.14	346	206	10	48	377	222	530	2e-12	79.7
rs:WP_010945247	topoisomerase I [[Haemophilus] ducreyi].	24.49	392	243	15	65	446	279	627	2e-12	79.7
tr:K0JTU7_SACES	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.06	360	208	14	37	377	287	614	2e-12	79.7
rs:WP_027567322	DNA topoisomerase I [Bradyrhizobium sp. URHA0013].	23.91	414	252	13	70	452	253	634	2e-12	79.7
rs:WP_042013731	DNA topoisomerase I [Aeromonas fluvialis].	24.05	420	261	14	49	452	259	636	2e-12	79.7
rs:WP_030629439	MULTISPECIES: DNA topoisomerase I [Streptomyces].	27.08	288	171	10	77	354	301	559	2e-12	79.7
rs:WP_006774712	DNA topoisomerase I [Hungatella hathewayi].	24.07	428	266	11	48	457	137	523	2e-12	79.3
rs:WP_013237965	MULTISPECIES: DNA topoisomerase I [Clostridium].	23.83	428	263	14	47	454	226	610	2e-12	79.7
rs:WP_045711205	DNA topoisomerase I [Streptomyces rubellomurinus].	26.19	294	166	12	77	354	301	559	2e-12	79.7
tr:D6E501_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.61	429	273	12	48	457	227	615	2e-12	79.7
rs:WP_015214496	DNA topoisomerase I [Anabaena cylindrica].	24.26	437	270	16	28	443	225	621	2e-12	79.7
rs:WP_027058799	DNA topoisomerase I [Mesorhizobium loti].	25.56	450	259	19	41	452	224	635	2e-12	79.7
tr:A0A015JH69_9GLOM	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EXX54264.1};	22.08	385	252	11	38	409	257	606	2e-12	79.7
tr:A0A087GMR1_ARAAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.71	350	220	12	40	379	258	570	2e-12	79.7
rs:WP_039468103	DNA topoisomerase I [Photobacterium gaetbulicola].	26.39	379	229	15	77	446	290	627	2e-12	79.7
rs:WP_010579950	DNA topoisomerase I [Lactobacillus vini].	23.93	443	277	16	34	458	226	626	2e-12	79.3
rs:WP_043570928	DNA topoisomerase I, partial [Actinopolyspora erythraea].	25.06	387	231	12	45	411	291	638	2e-12	79.7
rs:WP_005303279	MULTISPECIES: topoisomerase I [Aeromonas].	24.29	420	260	14	49	452	259	636	2e-12	79.7
rs:WP_045595170	DNA topoisomerase I [Vibrio vulnificus].	25.51	345	214	10	40	377	253	561	2e-12	79.7
rs:WP_014210569	DNA topoisomerase I [Mycobacterium rhodesiae].	26.88	346	198	13	77	399	296	609	2e-12	79.7
rs:WP_020005517	DNA topoisomerase I [Brachyspira innocens].	21.59	454	263	17	50	449	253	667	2e-12	79.7
tr:C0FQD4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.30	428	266	13	48	457	227	614	2e-12	79.7
tr:U2GQ65_9CORY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.37	339	202	10	30	354	244	545	2e-12	79.7
rs:WP_009133961	DNA topoisomerase I [Alistipes indistinctus].	25.94	293	178	7	47	334	223	481	2e-12	79.7
rs:WP_009669777	topoisomerase I [gamma proteobacterium IMCC1989].	25.91	413	247	16	48	446	265	632	2e-12	79.7
rs:WP_024108762	topoisomerase I [Dickeya dianthicola].	25.13	398	244	16	61	446	269	624	2e-12	79.7
rs:WP_037108519	DNA topoisomerase I [Rhodococcus fascians].	26.92	338	196	12	35	354	261	565	2e-12	79.7
rs:WP_010420670	DNA topoisomerase I [Anaerophaga thermohalophila].	26.82	261	158	7	77	335	259	488	2e-12	79.7
rs:WP_045698289	DNA topoisomerase I [Streptomyces rubellomurinus].	26.19	294	166	12	77	354	301	559	2e-12	79.7
rs:WP_032821503	topoisomerase I, partial [Oenococcus oeni].	32.67	150	98	2	250	397	1	149	2e-12	76.6
rs:WP_042007188	DNA topoisomerase I [Aeromonas dhakensis].	24.29	420	260	14	49	452	259	636	2e-12	79.7
rs:WP_022238238	DNA topoisomerase [Clostridium sp. CAG:343].	23.82	319	198	6	50	356	229	514	2e-12	79.3
rs:WP_012157752	DNA topoisomerase I [Frankia sp. EAN1pec].	24.87	382	237	12	41	404	330	679	2e-12	79.7
rs:WP_043810753	DNA topoisomerase I, partial [Allokutzneria albata].	26.89	357	216	11	37	377	249	576	2e-12	79.7
rs:WP_039383557	DNA topoisomerase I [Neochlamydia sp. TUME1].	23.60	428	269	13	43	452	236	623	2e-12	79.7
rs:WP_042632765	DNA topoisomerase I [Mycobacterium avium].	25.13	394	235	12	35	399	257	619	2e-12	79.7
tr:A0A0D2E9R9_9EURO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.94	355	223	9	39	377	259	582	2e-12	79.3
rs:WP_022476334	DNA topoisomerase [Clostridium sp. CAG:273].	22.12	425	274	11	47	454	226	610	2e-12	79.3
tr:A0A0D1WHV3_9EURO	SubName: Full=Strain CBS 40295 unplaced genomic scaffold supercont1.6, whole genome shotgun sequence {ECO:0000313|EMBL:KIV88395.1};	24.32	370	211	13	73	411	294	625	2e-12	79.3
rs:WP_005347733	topoisomerase I [Aeromonas veronii].	24.52	420	259	15	49	452	259	636	2e-12	79.7
rs:WP_042242210	DNA topoisomerase I [Neochlamydia sp. S13].	23.60	428	269	13	43	452	236	623	2e-12	79.7
rs:WP_035953383	DNA topoisomerase I [Frankia sp. EUN1f].	26.10	364	219	12	41	386	292	623	2e-12	79.7
rs:WP_007450295	DNA topoisomerase I [Streptomyces sp. W007].	26.55	290	170	10	77	354	301	559	2e-12	79.7
rs:XP_001991334	GH12112 [Drosophila grimshawi].	25.14	354	222	14	37	382	256	574	2e-12	79.7
tr:K6K499_KLEOX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.40	378	235	14	77	446	284	622	2e-12	79.7
rs:WP_003865910	DNA topoisomerase I [Holdemanella biformis].	24.19	401	235	13	75	452	253	607	2e-12	79.3
rs:WP_023830660	DNA topoisomerase I [Mesorhizobium sp. L103C119B0].	25.06	431	249	17	60	452	241	635	2e-12	79.7
rs:WP_020985551	DNA topoisomerase I [Leptospira kmetyi].	21.71	433	282	14	40	450	211	608	2e-12	79.3
rs:WP_038020773	DNA topoisomerase I [Tatumella morbirosei].	24.68	393	236	14	77	452	284	633	2e-12	79.7
rs:WP_031719306	DNA topoisomerase I [Mycobacterium tuberculosis].	25.59	383	230	11	41	399	271	622	2e-12	79.7
rs:WP_006626394	DNA topoisomerase I [Bulleidia extructa].	23.91	435	253	14	47	454	225	608	2e-12	79.3
rs:WP_034767886	DNA topoisomerase I [Hyphomonas sp. CY54-11-8].	23.74	438	275	12	41	452	225	629	2e-12	79.7
rs:WP_045982897	DNA topoisomerase I [Paracoccus sp. S4493].	24.04	441	235	15	77	454	259	662	2e-12	79.7
rs:WP_033274891	MULTISPECIES: DNA topoisomerase I [Actinobacteria].	26.62	293	166	11	77	354	299	557	2e-12	79.7
rs:WP_036855184	DNA topoisomerase I [Prevotella amnii].	25.75	268	157	7	77	334	253	488	2e-12	79.3
rs:WP_044623863	DNA topoisomerase I [Photobacterium gaetbulicola].	26.39	379	229	15	77	446	290	627	2e-12	79.7
rs:WP_031823979	DNA topoisomerase III, partial [Staphylococcus aureus].	30.77	169	107	5	284	450	3	163	2e-12	76.6
rs:WP_022293461	DNA topoisomerase [Eubacterium rectale CAG:36].	22.61	429	273	12	48	457	227	615	2e-12	79.3
rs:WP_025017587	DNA topoisomerase III [Bacteroides sartorii].	24.80	379	242	11	18	385	216	562	2e-12	79.3
rs:WP_019808041	DNA topoisomerase I [Osedax symbiont Rs1].	25.00	392	230	15	77	452	295	638	2e-12	79.7
rs:WP_014953328	DNA topoisomerase I [alpha proteobacterium HIMB5].	23.50	434	267	14	51	454	234	632	2e-12	79.7
rs:WP_041315862	DNA topoisomerase I, partial [Saccharothrix espanaensis].	27.35	362	208	14	37	377	245	572	2e-12	79.7
rs:WP_007603302	DNA topoisomerase I [Bradyrhizobium sp. WSM1253].	24.40	414	250	15	70	452	253	634	2e-12	79.7
rs:WP_038551634	DNA topoisomerase I [Nocardia nova].	26.09	322	188	10	47	356	267	550	2e-12	79.7
rs:WP_021667426	DNA topoisomerase I [Porphyromonas sp. oral taxon 278].	26.81	276	169	7	61	334	235	479	2e-12	79.3
rs:WP_006347634	DNA topoisomerase I [Streptomyces tsukubaensis].	26.96	293	165	11	77	354	302	560	2e-12	79.7
rs:WP_031062705	DNA topoisomerase I [Streptomyces sp. NRRL F-5527].	26.62	293	166	11	77	354	299	557	2e-12	79.7
tr:A0A0C7NE35_9SACH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.67	374	226	12	39	391	265	607	2e-12	79.3
rs:WP_027553089	DNA topoisomerase I [Bradyrhizobium sp. Cp5.3].	24.41	426	253	13	61	452	244	634	2e-12	79.7
tr:A0A087W023_ECHMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.83	470	263	15	39	450	257	689	2e-12	79.7
rs:WP_045939811	DNA topoisomerase I [Streptomyces sp. NRRL S-495].	26.19	294	166	12	77	354	301	559	2e-12	79.7
rs:WP_038471906	DNA topoisomerase I [Cedecea neteri].	24.73	376	240	12	77	446	284	622	2e-12	79.3
rs:WP_009501685	DNA topoisomerase I subunit omega [Moraxella macacae].	25.33	300	180	11	61	354	307	568	2e-12	79.7
rs:XP_456010	hypothetical protein [Kluyveromyces lactis NRRL Y-1140].	23.56	365	221	10	40	378	277	609	2e-12	79.3
rs:WP_033178772	DNA topoisomerase I [Mycoplasma anseris].	23.01	439	265	16	31	452	213	595	2e-12	79.3
rs:WP_039445801	DNA topoisomerase I [Porphyromonas gulae].	28.25	269	151	8	77	338	248	481	2e-12	79.3
rs:XP_009765588	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Nicotiana sylvestris].	23.27	434	268	16	39	453	205	592	2e-12	79.3
rs:WP_031268127	DNA topoisomerase I, partial [Corynebacterium pseudodiphtheriticum].	25.37	339	202	10	30	354	244	545	2e-12	79.7
rs:WP_026890284	DNA topoisomerase I [[Clostridium] aerotolerans].	23.89	427	268	12	48	457	230	616	2e-12	79.3
rs:WP_047416616	DNA topoisomerase I [Cellulophaga sp. Hel_I_12].	26.73	303	176	8	36	334	218	478	2e-12	79.3
rs:WP_020110968	DNA topoisomerase I [Rhodococcus sp. 114MFTsu3.1].	26.92	338	196	12	35	354	261	565	2e-12	79.7
rs:WP_045789265	DNA topoisomerase I [Aeromonas hydrophila].	24.74	392	237	14	77	452	287	636	3e-12	79.3
rs:WP_028934170	DNA topoisomerase I [Pseudonocardia spinosispora].	26.38	326	198	10	42	354	290	586	3e-12	79.7
rs:WP_037183150	DNA topoisomerase I [Rhodococcus fascians].	26.92	338	196	12	35	354	261	565	3e-12	79.7
rs:XP_009765587	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Nicotiana sylvestris].	23.27	434	268	16	39	453	254	641	3e-12	79.3
rs:WP_028442111	DNA topoisomerase I [Streptomyces sp. DpondAA-B6].	27.08	288	171	10	77	354	301	559	3e-12	79.7
rs:WP_037877861	DNA topoisomerase I [Streptomyces sp. NTK 937].	27.08	288	171	10	77	354	301	559	3e-12	79.7
rs:WP_035892922	DNA topoisomerase I [Kluyvera ascorbata].	26.69	281	169	8	77	354	284	530	3e-12	79.3
rs:XP_002071612	GK10076 [Drosophila willistoni].	23.78	349	227	12	40	382	259	574	3e-12	79.3
rs:WP_029170723	DNA topoisomerase I, partial [Cloacimonetes bacterium SCGC AAA255-C20].	23.53	425	251	16	47	452	54	423	3e-12	79.0
rs:WP_023028183	DNA topoisomerase I [Corynebacterium sp. KPL1824].	24.93	361	214	12	47	384	266	592	3e-12	79.7
rs:WP_033136942	DNA topoisomerase I [Aeromonas sp. 4287D].	24.05	420	261	14	49	452	259	636	3e-12	79.3
rs:WP_000681473	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	3e-12	79.3
tr:A0A017SMB4_9EURO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.40	359	212	9	65	395	285	608	3e-12	79.3
rs:WP_009579003	DNA topoisomerase I [Fulvivirga imtechensis].	24.92	297	189	8	47	340	219	484	3e-12	79.3
rs:WP_006175684	topoisomerase I [Enterobacter cancerogenus].	25.26	380	233	13	77	446	284	622	3e-12	79.3
rs:WP_028870147	DNA topoisomerase I [Psychromonas arctica].	26.11	383	227	15	77	446	292	631	3e-12	79.3
rs:WP_010021434	DNA topoisomerase I [Lactobacillus fructivorans].	24.44	405	245	14	65	452	262	622	3e-12	79.3
rs:WP_046017957	DNA topoisomerase I [Marinomonas sp. S3726].	24.87	398	245	17	62	446	274	630	3e-12	79.3
rs:WP_024278932	DNA topoisomerase I [Xanthobacter sp. 126].	27.14	420	237	15	69	454	253	637	3e-12	79.3
rs:WP_035537897	DNA topoisomerase I [Hyphomonas oceanitis].	24.53	424	259	13	57	452	239	629	3e-12	79.3
tr:D2TAL0_ERWP6	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.79	392	229	17	77	452	259	608	3e-12	79.3
rs:WP_012832491	DNA topoisomerase I [Gordonia bronchialis].	25.53	329	199	10	41	354	266	563	3e-12	79.7
rs:WP_047858678	DNA topoisomerase I [Archangium gephyra].	24.11	448	269	16	41	452	301	713	3e-12	79.3
rs:WP_045855064	DNA topoisomerase I [Raoultella terrigena].	26.12	379	231	15	77	446	284	622	3e-12	79.3
rs:WP_018644533	DNA topoisomerase I [Bradyrhizobium japonicum].	24.11	423	258	12	61	452	244	634	3e-12	79.3
rs:WP_028171575	MULTISPECIES: DNA topoisomerase I [Bradyrhizobium].	23.64	423	260	13	61	452	244	634	3e-12	79.3
tr:K9G3X9_PEND1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.39	342	195	8	41	359	204	501	3e-12	79.0
tr:A0A0B8NR25_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.93	381	232	13	77	446	290	627	3e-12	79.3
rs:WP_000681523	DNA topoisomerase I [Helicobacter pylori].	25.32	395	231	16	74	450	251	599	3e-12	79.3
rs:WP_014299590	DNA topoisomerase I [Bacteroides fragilis].	25.00	264	158	7	77	334	253	482	3e-12	79.3
rs:WP_028901497	DNA topoisomerase I [Prevotella corporis].	23.97	388	251	10	27	387	204	574	3e-12	79.3
rs:WP_041145185	DNA topoisomerase I [Raoultella ornithinolytica].	26.12	379	231	15	77	446	284	622	3e-12	79.3
rs:WP_007878636	DNA topoisomerase I subunit omega [Ochrobactrum sp. CDB2].	25.58	430	248	15	60	452	241	635	3e-12	79.3
rs:WP_040250119	DNA topoisomerase I [Streptomyces albus].	26.96	293	165	11	77	354	298	556	3e-12	79.3
rs:WP_037612612	DNA topoisomerase [Streptococcus sp. OBRC6].	24.32	329	213	10	74	397	278	575	3e-12	79.0
tr:A0A061RF57_9CHLO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.67	420	240	16	77	454	313	706	3e-12	79.7
tr:T5BWA9_AJEDE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.95	316	180	10	73	369	294	574	3e-12	79.3
rs:WP_025415897	DNA topoisomerase I [Rhizobium leguminosarum].	25.42	421	249	16	67	452	248	638	3e-12	79.3
rs:WP_018536494	DNA topoisomerase I [Streptomyces sp. MspMP-M5].	27.34	289	169	10	77	354	301	559	3e-12	79.3
rs:WP_043762019	DNA topoisomerase I [Aeromonas taiwanensis].	25.07	347	214	10	49	384	259	570	3e-12	79.3
tr:H2Z241_CIOSA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.48	361	214	12	60	405	284	604	3e-12	79.3
rs:WP_046530015	DNA topoisomerase I [Cellulomonas sp. FA1].	27.38	336	195	9	42	356	253	560	3e-12	79.3
rs:WP_034994474	DNA topoisomerase I [Lactobacillus vini].	23.93	443	277	16	34	458	222	622	3e-12	79.3
rs:WP_039531544	DNA topoisomerase I [Pectobacterium carotovorum].	25.06	399	243	13	61	446	268	623	3e-12	79.3
tr:A0A0E4FZD9_9BRAD	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:BAR62987.1};	23.64	423	260	13	61	452	244	634	3e-12	79.3
tr:C5GXA3_AJEDR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.95	316	180	10	73	369	296	576	3e-12	79.0
rs:WP_030989852	DNA topoisomerase I [Streptomyces sp. NRRL S-1813].	26.74	288	172	9	77	354	300	558	3e-12	79.3
rs:WP_024305136	DNA topoisomerase I, partial [Cloacimonetes bacterium SCGC AAA252-P10].	23.53	425	251	16	47	452	230	599	3e-12	79.3
rs:WP_022822824	DNA topoisomerase I [Hymenobacter norwichensis].	28.91	294	176	9	47	334	220	486	3e-12	79.3
rs:WP_012667988	topoisomerase I [Erwinia pyrifoliae].	26.79	392	229	17	77	452	284	633	3e-12	79.3
rs:WP_039142858	DNA topoisomerase I [Lactobacillus fructivorans].	24.44	405	245	14	65	452	266	626	3e-12	79.3
rs:WP_043391541	DNA topoisomerase I [Cystobacter violaceus].	24.55	448	267	17	41	452	301	713	3e-12	79.3
rs:XP_814477	DNA topoisomerase III [Trypanosoma cruzi strain CL Brener].	25.15	342	205	9	47	380	269	567	3e-12	79.3
tr:V5BE78_TRYCR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.66	343	202	10	47	380	9	307	3e-12	79.3
rs:WP_036848414	DNA topoisomerase I [Porphyromonas cangingivalis].	25.47	318	197	8	24	337	198	479	3e-12	79.3
rs:WP_030543868	DNA topoisomerase I [Streptomyces albus].	25.94	293	168	11	77	354	301	559	3e-12	79.3
rs:WP_045590468	DNA topoisomerase I [Vibrio vulnificus].	25.51	345	214	10	40	377	253	561	3e-12	79.3
tr:D3D5Q6_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.10	364	219	12	41	386	301	632	3e-12	79.3
gpu:CP011230_891	DNA topoisomerase I [[Haemophilus] ducreyi]	24.49	392	243	15	65	446	279	627	3e-12	79.3
tr:W5T898_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.09	322	188	10	47	356	302	585	3e-12	79.3
rs:WP_046200490	DNA topoisomerase I [Porphyromonas gulae].	27.42	299	165	9	47	338	228	481	3e-12	79.3
rs:WP_004577989	Topoisomerase IA, partial [nanoarchaeote Nst1].	27.11	273	163	8	56	328	255	491	3e-12	79.0
rs:WP_038257868	DNA topoisomerase I [Yokenella regensburgei].	27.05	281	168	8	77	354	284	530	3e-12	79.3
rs:WP_038939790	DNA topoisomerase I [Vibrio vulnificus].	25.51	345	214	10	40	377	253	561	3e-12	79.3
rs:WP_019585340	DNA topoisomerase I [Deinococcus apachensis].	25.86	321	195	10	37	344	247	537	3e-12	79.3
rs:WP_019829856	topoisomerase I [Vibrio cholerae].	25.98	381	228	15	77	446	292	629	3e-12	79.3
rs:WP_014024778	DNA topoisomerase I [Lactococcus garvieae].	21.97	437	278	13	34	452	239	630	3e-12	79.3
rs:WP_032688111	MULTISPECIES: DNA topoisomerase I [Enterobacteriaceae].	26.49	385	222	15	77	446	284	622	3e-12	79.3
rs:WP_044017930	DNA topoisomerase I [Hymenobacter sp. APR13].	28.33	293	178	9	47	334	220	485	3e-12	79.3
rs:WP_000681467	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	3e-12	79.3
sp:TOP3_CAEEL	RecName: Full=DNA topoisomerase 3; EC=5.99.1.2; AltName: Full=DNA topoisomerase III;	25.76	361	221	11	39	387	260	585	3e-12	79.3
rs:WP_023289334	MULTISPECIES: DNA topoisomerase 1 [Klebsiella].	26.09	391	216	15	77	446	284	622	3e-12	79.3
rs:WP_028297149	DNA topoisomerase I [Olivibacter sitiensis].	25.57	305	184	8	36	335	219	485	3e-12	79.3
rs:WP_029391222	DNA topoisomerase I [Streptomyces xiaopingdaonensis].	26.30	289	172	10	77	354	301	559	3e-12	79.3
rs:WP_045621564	DNA topoisomerase I [Vibrio vulnificus].	25.80	345	213	10	40	377	253	561	3e-12	79.3
rs:WP_022490361	DNA topoisomerase [Clostridium sp. CAG:567].	22.54	426	271	11	47	454	226	610	3e-12	79.0
rs:WP_026817248	DNA topoisomerase I [Arenimonas composti].	28.52	305	172	11	66	354	254	528	3e-12	79.3
rs:WP_008817324	MULTISPECIES: DNA topoisomerase I [unclassified Erysipelotrichaceae (miscellaneous)].	24.58	415	245	13	61	452	238	607	3e-12	79.3
rs:WP_029883572	MULTISPECIES: DNA topoisomerase I [Enterobacter].	24.93	381	233	15	77	446	284	622	3e-12	79.3
tr:Q1QKM0_NITHX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.26	437	262	13	47	454	265	661	3e-12	79.3
rs:WP_048459492	DNA topoisomerase I [Streptomyces sp. HNS054].	26.62	293	166	11	77	354	299	557	3e-12	79.3
rs:WP_024551692	MULTISPECIES: DNA topoisomerase I [Enterobacteriaceae].	25.19	385	235	12	13	386	228	570	3e-12	79.3
rs:WP_020941373	DNA topoisomerase I [Streptomyces collinus].	26.96	293	165	11	77	354	299	557	3e-12	79.3
tr:A0A034W295_BACDO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.89	452	270	14	35	451	276	688	3e-12	79.3
rs:WP_044882774	DNA topoisomerase I [Neochlamydia sp. EPS4].	23.60	428	269	13	43	452	236	623	3e-12	79.3
rs:XP_011942699	PREDICTED: DNA topoisomerase 3-alpha [Cercocebus atys].	25.12	414	262	13	60	450	310	698	3e-12	79.3
rs:XP_001847754	DNA topoisomerase 3-alpha [Culex quinquefasciatus].	23.37	445	273	13	37	452	253	658	3e-12	79.3
rs:WP_039196769	DNA topoisomerase I [Actinobacillus equuli].	24.82	411	256	16	47	446	261	629	3e-12	79.3
rs:WP_014974405	DNA topoisomerase I [Leuconostoc carnosum].	23.79	412	233	16	69	452	272	630	3e-12	79.0
rs:WP_045492721	DNA topoisomerase I [Vibrio sp. 151112A].	26.25	320	191	10	77	386	291	575	3e-12	79.3
rs:WP_021174553	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	3e-12	79.3
rs:WP_038702721	hypothetical protein, partial [Sphingobacterium sp. ML3W].	27.24	268	153	7	77	335	250	484	3e-12	79.3
tr:G3XZ45_ASPNA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.72	346	197	10	45	369	267	573	3e-12	79.0
rs:WP_039150646	DNA topoisomerase I [Gallibacterium anatis].	25.07	375	240	12	77	446	290	628	3e-12	79.3
rs:WP_043404297	DNA topoisomerase I [Streptomyces pluripotens].	26.71	292	167	11	77	354	299	557	3e-12	79.3
rs:WP_013618934	DNA topoisomerase I [Bacteroides salanitronis].	27.88	269	144	8	77	334	249	478	3e-12	79.3
rs:WP_031524090	DNA topoisomerase I, partial [Cronobacter sp. 1383].	26.17	321	191	12	77	386	284	569	3e-12	79.0
rs:WP_039649491	MULTISPECIES: DNA topoisomerase I [Streptomyces].	26.71	292	167	11	77	354	299	557	3e-12	79.3
rs:WP_021752225	DNA topoisomerase I [Gemella bergeri].	22.09	430	275	11	40	452	218	604	3e-12	79.0
rs:WP_006845568	DNA topoisomerase I [Weissella koreensis].	23.34	437	263	14	40	452	237	625	3e-12	79.0
rs:WP_007491977	DNA topoisomerase I [Streptomyces zinciresistens].	26.62	293	166	11	77	354	299	557	3e-12	79.3
tr:G9Z6S3_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.05	281	168	8	77	354	296	542	3e-12	79.3
rs:WP_033584725	DNA topoisomerase I [Helicobacter pylori].	24.94	393	235	14	74	450	251	599	3e-12	79.0
rs:WP_000681492	DNA topoisomerase I [Helicobacter pylori].	25.32	395	231	16	74	450	251	599	3e-12	79.0
rs:WP_000681457	DNA topoisomerase I [Helicobacter pylori].	24.94	393	235	14	74	450	251	599	3e-12	79.0
rs:WP_002608927	DNA topoisomerase I [[Clostridium] innocuum].	24.58	415	245	13	61	452	238	607	3e-12	79.3
rs:WP_009589046	MULTISPECIES: DNA topoisomerase I [Clostridiales].	24.58	415	245	13	61	452	238	607	3e-12	79.3
rs:WP_009162132	DNA topoisomerase I [Prevotella saccharolytica].	25.82	275	142	9	77	334	252	481	3e-12	79.3
rs:WP_005488609	DNA topoisomerase I [Halanaerobium saccharolyticum].	25.34	438	257	18	41	456	222	611	3e-12	79.0
rs:WP_018122573	hypothetical protein [Wohlfahrtiimonas chitiniclastica].	26.88	398	213	16	56	416	243	599	3e-12	79.3
rs:WP_023701185	DNA topoisomerase I [Mesorhizobium sp. LSJC264A00].	24.89	446	259	18	45	452	228	635	3e-12	79.3
rs:WP_006309612	DNA topoisomerase I [Facklamia languida].	24.13	431	263	16	41	452	219	604	3e-12	79.0
rs:WP_045422306	DNA topoisomerase I [Vibrio jasicida].	26.25	320	191	10	77	386	291	575	3e-12	79.3
rs:WP_043318076	DNA topoisomerase I [Microbulbifer sp. HZ11].	23.84	411	258	11	47	446	266	632	3e-12	79.3
rs:WP_033166717	DNA topoisomerase I [Clostridium sp. KNHs205].	22.09	412	267	10	61	457	238	610	3e-12	79.0
rs:WP_039446508	DNA topoisomerase I [Vibrio vulnificus].	25.51	345	214	10	40	377	253	561	3e-12	79.3
rs:WP_008685770	DNA topoisomerase I [Desulfovibrio sp. 3_1_syn3].	25.95	420	230	17	61	459	236	595	3e-12	79.0
tr:A0A063BQ72_9HYPO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KDB11172.1};	25.89	282	165	7	61	335	279	523	3e-12	79.0
rs:WP_024503572	DNA topoisomerase I [Mesorhizobium ciceri].	25.94	451	256	21	41	452	224	635	3e-12	79.3
rs:WP_035582537	DNA topoisomerase I [Hyphomonas jannaschiana].	23.97	438	274	12	41	452	225	629	3e-12	79.3
rs:WP_044601245	hypothetical protein [Candidatus Babela massiliensis].	24.11	423	271	17	47	452	231	620	3e-12	79.0
rs:WP_042642291	DNA topoisomerase I [Aeromonas eucrenophila].	24.29	420	260	14	49	452	259	636	3e-12	79.3
rs:WP_041358070	DNA topoisomerase I [Nitrobacter hamburgensis].	24.26	437	262	13	47	454	240	636	3e-12	79.3
tr:A0A078HPQ0_BRANA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.87	465	291	15	18	451	244	676	3e-12	79.3
rs:WP_001939020	DNA topoisomerase I [Helicobacter pylori].	24.43	397	232	15	74	450	251	599	3e-12	79.0
rs:WP_037143270	DNA topoisomerase I [Rhodococcus fascians].	26.92	338	196	12	35	354	261	565	3e-12	79.3
rs:WP_031020068	DNA topoisomerase I [Streptomyces sp. NRRL S-1314].	26.62	293	166	11	77	354	299	557	3e-12	79.3
rs:WP_006132575	DNA topoisomerase I [Streptomyces gancidicus].	26.62	293	166	11	77	354	299	557	3e-12	79.3
rs:WP_017421991	topoisomerase I [Vibrio vulnificus].	25.51	345	214	10	40	377	253	561	3e-12	79.3
tr:M0WQP2_HORVD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.84	354	209	11	39	378	266	583	3e-12	79.0
rs:WP_009603463	topoisomerase I [Vibrio caribbeanicus].	27.18	298	167	9	69	354	276	535	3e-12	79.3
rs:WP_023582278	DNA topoisomerase I [Proteus hauseri].	26.48	389	228	16	80	452	287	633	3e-12	79.3
rs:WP_004089716	topoisomerase I [Xylella fastidiosa].	45.95	74	40	0	260	333	1	74	3e-12	73.2
rs:WP_036851281	DNA topoisomerase I [Porphyromonas cangingivalis].	25.47	318	197	8	24	337	198	479	3e-12	79.0
rs:WP_010474837	DNA topoisomerase I [Acaryochloris sp. CCMEE 5410].	24.77	428	262	14	32	445	227	608	3e-12	79.0
rs:WP_005791192	MULTISPECIES: DNA topoisomerase I [Bacteroides].	25.00	264	158	7	77	334	253	482	3e-12	79.0
rs:WP_029252025	DNA topoisomerase I [Paraoerskovia marina].	25.48	361	198	12	35	356	243	571	3e-12	79.3
rs:WP_024885813	DNA topoisomerase I [Streptomyces sp. CNH189].	26.62	293	166	11	77	354	299	557	3e-12	79.3
rs:WP_043851335	DNA topoisomerase I [Aeromonas sp. L_1B5_3].	24.58	419	260	14	49	452	259	636	3e-12	79.3
rs:WP_032569135	DNA topoisomerase I [Bacteroides fragilis].	25.00	264	158	7	77	334	253	482	3e-12	79.0
rs:WP_008770105	MULTISPECIES: DNA topoisomerase I [Bacteroides].	25.00	264	158	7	77	334	253	482	3e-12	79.0
rs:WP_035341963	DNA topoisomerase I [Dickeya sp. DW 0440].	25.38	398	251	14	57	446	263	622	3e-12	79.3
tr:F7BHS6_CALJA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.53	442	270	17	40	455	289	688	3e-12	79.3
rs:WP_029290883	DNA topoisomerase I [Cellulomonas sp. HZM].	27.49	331	197	10	42	356	251	554	3e-12	79.3
rs:WP_039489493	DNA topoisomerase I [Pectobacterium carotovorum].	25.06	399	243	13	61	446	268	623	3e-12	79.3
rs:XP_003240406	PREDICTED: DNA topoisomerase 3-beta-1 [Acyrthosiphon pisum].	22.36	407	256	12	38	424	259	625	3e-12	79.3
rs:WP_046280474	DNA topoisomerase I, partial [Limnoraphis robusta].	26.10	341	206	12	77	401	17	327	3e-12	79.0
rs:WP_017262381	hypothetical protein [Lactobacillus rossiae].	24.94	433	229	19	67	454	277	658	3e-12	79.0
rs:WP_032534215	DNA topoisomerase I [Bacteroides fragilis].	25.00	264	158	7	77	334	253	482	3e-12	79.0
rs:WP_010993765	DNA topoisomerase I [Bacteroides fragilis].	25.00	264	158	7	77	334	253	482	3e-12	79.0
rs:WP_043502860	DNA topoisomerase I [Streptomyces glaucescens].	26.96	293	165	11	77	354	299	557	3e-12	79.3
rs:WP_036937101	DNA topoisomerase I [Proteus vulgaris].	26.22	389	229	16	80	452	287	633	3e-12	79.3
rs:WP_039473052	DNA topoisomerase I [Pectobacterium carotovorum].	25.06	399	243	13	61	446	268	623	3e-12	79.3
rs:WP_024341083	DNA topoisomerase I [Bradyrhizobium japonicum].	24.55	440	253	15	47	452	240	634	3e-12	79.3
rs:WP_010295184	topoisomerase I [Pectobacterium carotovorum].	25.06	399	243	13	61	446	268	623	3e-12	79.0
rs:WP_019982557	DNA topoisomerase I [Streptomyces sp. Amel2xE9].	26.96	293	165	11	77	354	299	557	3e-12	79.3
rs:XP_001697150	hypothetical protein CHLREDRAFT_138607, partial [Chlamydomonas reinhardtii].	22.17	415	268	11	39	434	264	642	3e-12	79.0
rs:WP_022124364	DNA topoisomerase [Clostridium sp. CAG:510].	23.93	422	268	11	48	454	266	649	3e-12	79.0
rs:XP_662159	hypothetical protein AN4555.2 [Aspergillus nidulans FGSC A4].	26.02	342	176	10	61	369	276	573	3e-12	79.0
tr:A0A090BFX1_KLUMA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.99	396	235	12	18	378	254	618	3e-12	79.0
rs:WP_047109379	DNA topoisomerase I [Vibrio vulnificus].	25.51	345	214	10	40	377	253	561	3e-12	79.0
rs:WP_001924354	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	3e-12	79.0
rs:WP_028526255	DNA topoisomerase I [Runella limosa].	27.09	299	182	8	45	340	220	485	3e-12	79.0
rs:WP_018835882	MULTISPECIES: DNA topoisomerase I [Streptomyces].	26.37	383	232	14	47	411	269	619	3e-12	79.3
rs:WP_037753604	DNA topoisomerase I [Streptomyces sp. CNQ-525].	26.37	383	232	14	47	411	269	619	3e-12	79.3
rs:WP_030751088	DNA topoisomerase I [Streptomyces sp. NRRL F-5135].	26.81	317	188	11	77	379	299	585	3e-12	79.3
rs:WP_034585299	DNA topoisomerase I [Helicobacter magdeburgensis].	24.37	435	262	17	41	454	224	612	3e-12	79.0
rs:WP_026449335	DNA topoisomerase I [Actinopolyspora mortivallis].	23.99	396	254	12	35	411	267	634	3e-12	79.3
rs:WP_037138139	DNA topoisomerase I [Rhizobium leguminosarum].	24.83	439	267	15	47	452	230	638	3e-12	79.0
rs:WP_010673895	MULTISPECIES: topoisomerase I [Aeromonas].	24.57	346	217	9	49	384	259	570	3e-12	79.0
rs:WP_022223943	DNA topoisomerase [Clostridium sp. CAG:253].	24.06	424	267	12	47	454	226	610	3e-12	79.0
rs:WP_017409144	topoisomerase I [Aeromonas hydrophila].	24.29	420	260	14	49	452	259	636	3e-12	79.0
rs:WP_013571404	topoisomerase I [Vibrio vulnificus].	25.51	345	214	10	40	377	253	561	3e-12	79.0
rs:WP_003640563	DNA topoisomerase I [Lactobacillus plantarum].	23.82	403	237	16	77	457	283	637	3e-12	79.0
rs:WP_001922728	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	3e-12	79.0
rs:WP_033595303	DNA topoisomerase I [Helicobacter pylori].	25.76	396	228	17	74	450	251	599	3e-12	79.0
rs:WP_014832223	topoisomerase I [Enterobacter cloacae].	24.93	381	233	15	77	446	284	622	3e-12	79.0
rs:WP_019009533	DNA topoisomerase I [Deinococcus aquatilis].	26.39	341	190	13	23	344	243	541	3e-12	79.0
rs:WP_023763638	DNA topoisomerase I [Mesorhizobium sp. LNHC232B00].	24.78	448	265	18	41	452	224	635	3e-12	79.0
rs:WP_040179383	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	3e-12	79.0
rs:WP_005814152	DNA topoisomerase I [Bacteroides fragilis].	25.00	264	158	7	77	334	253	482	3e-12	79.0
rs:WP_021510115	topoisomerase I [Pantoea dispersa].	27.48	393	225	18	77	452	284	633	3e-12	79.0
rs:XP_011252576	PREDICTED: DNA topoisomerase 3-alpha [Camponotus floridanus].	25.25	404	234	14	73	449	339	701	3e-12	79.3
tr:M3LLJ8_HELPX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.76	396	228	17	74	450	251	599	3e-12	79.0
tr:V6DHF8_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.11	423	271	17	47	452	244	633	3e-12	79.0
rs:WP_034384176	DNA topoisomerase I [Herbidospora cretacea].	26.90	342	213	11	42	374	262	575	4e-12	79.0
tr:Q5I6D5_TRYCR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.15	342	205	9	47	380	269	567	4e-12	79.0
rs:WP_030035662	DNA topoisomerase I [Clostridium botulinum].	22.25	427	243	13	77	449	256	647	4e-12	79.0
rs:WP_016574364	MULTISPECIES: DNA topoisomerase I [Streptomyces].	26.99	289	170	10	77	354	301	559	4e-12	79.0
rs:WP_000681529	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	79.0
rs:WP_029653650	DNA topoisomerase I [Marinobacter daepoensis].	23.22	422	269	12	36	446	255	632	4e-12	79.0
rs:WP_024380179	hypothetical protein [Streptococcus suis].	24.66	369	218	13	47	396	250	577	4e-12	78.6
rs:WP_006778033	DNA topoisomerase III, partial [[Clostridium] hathewayi].	29.12	182	122	4	34	212	20	197	4e-12	75.5
rs:WP_020967061	DNA topoisomerase I [Chlamydia trachomatis].	23.36	428	257	16	47	449	241	622	4e-12	79.0
rs:WP_008582879	DNA topoisomerase I [Niabella soli].	26.32	266	165	7	77	340	254	490	4e-12	79.0
tr:F9VDX9_LACGL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.90	420	266	12	50	452	277	651	4e-12	79.0
rs:WP_038419681	MULTISPECIES: DNA topoisomerase I [Enterobacter].	24.93	381	233	15	77	446	284	622	4e-12	79.0
rs:WP_046887713	MULTISPECIES: DNA topoisomerase I [Enterobacter].	24.93	381	233	15	77	446	284	622	4e-12	79.0
rs:WP_020612107	DNA topoisomerase I [Spirochaeta bajacaliforniensis].	26.17	321	199	8	41	354	254	543	4e-12	79.0
rs:WP_001920473	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	79.0
rs:WP_042636706	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	4e-12	79.0
rs:WP_000681452	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	4e-12	79.0
rs:WP_000681424	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	4e-12	79.0
rs:WP_038848444	DNA topoisomerase I [Campylobacter coli].	24.54	436	249	18	41	450	219	600	4e-12	79.0
rs:WP_044203945	DNA topoisomerase I [Flammeovirga sp. OC4].	28.38	303	173	10	36	334	218	480	4e-12	79.0
tr:G4AZM2_AGGAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.72	352	220	12	102	446	5	318	4e-12	78.6
rs:WP_011080010	topoisomerase I [Vibrio vulnificus].	25.51	345	214	10	40	377	253	561	4e-12	79.0
rs:WP_035421699	DNA topoisomerase I [Lactobacillus florum].	23.83	407	254	14	61	452	257	622	4e-12	79.0
rs:WP_045955369	DNA topoisomerase I [Vibrio sp. S2757].	25.59	340	190	11	69	386	276	574	4e-12	79.0
rs:WP_032590962	DNA topoisomerase I [Bacteroides fragilis].	25.00	264	158	7	77	334	253	482	4e-12	79.0
tr:A0A072C6M9_RHILP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.83	439	267	15	47	452	226	634	4e-12	79.0
rs:WP_028118478	DNA topoisomerase I [Facklamia sourekii].	24.75	408	236	18	67	452	245	603	4e-12	79.0
rs:WP_033753531	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	79.0
gp:AK221174_1	putative DNA topoisomerase III beta [Arabidopsis thaliana]	23.92	347	211	12	18	351	233	539	4e-12	79.0
tr:A0A0C3FUZ3_9HOMO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.27	354	210	12	39	378	260	576	4e-12	78.6
rs:WP_039056062	DNA topoisomerase I [Enterobacter sp. Bisph1].	25.53	380	232	14	77	446	284	622	4e-12	79.0
rs:WP_025036761	DNA topoisomerase I [Bradyrhizobium sp. DOA9].	24.35	423	257	12	61	452	244	634	4e-12	79.0
rs:WP_040337460	DNA topoisomerase I [Candidatus Blastococcus massiliensis].	25.41	362	213	12	42	378	293	622	4e-12	79.0
rs:WP_000681512	DNA topoisomerase I [Helicobacter pylori].	25.76	396	228	17	74	450	251	599	4e-12	79.0
rs:WP_000681433	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	4e-12	79.0
rs:WP_000681426	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	4e-12	79.0
rs:WP_004861033	MULTISPECIES: topoisomerase I [Enterobacteriaceae].	26.49	385	222	15	77	446	284	622	4e-12	79.0
rs:WP_038839415	DNA topoisomerase I [Campylobacter coli].	24.77	432	253	17	41	450	219	600	4e-12	79.0
rs:WP_012742655	DNA topoisomerase I [Eubacterium rectale].	22.38	429	274	12	48	457	227	615	4e-12	79.0
rs:WP_016757400	MULTISPECIES: DNA topoisomerase I [Leptospira].	22.40	442	275	15	40	456	211	609	4e-12	78.6
tr:A0A069YQP7_ECOLX	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:KDU49610.1};	32.09	134	87	2	311	443	11	141	4e-12	75.5
tr:M3QQR9_HELPX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.06	395	232	16	74	450	251	599	4e-12	79.0
rs:WP_033765728	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	79.0
rs:WP_036437057	DNA topoisomerase I [Mycoplasma elephantis].	25.66	378	223	12	89	452	269	602	4e-12	78.6
rs:WP_022656303	DNA topoisomerase I [Desulfovibrio sp. Dsv1].	22.09	412	279	10	47	450	223	600	4e-12	79.0
rs:WP_020175813	DNA topoisomerase I [Methyloferula stellata].	25.84	449	251	15	45	452	228	635	4e-12	79.0
rs:WP_030518821	DNA topoisomerase I [Nocardia sp. NRRL WC-3656].	26.09	322	188	10	47	356	270	553	4e-12	79.0
rs:WP_000681521	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	4e-12	79.0
rs:WP_024368809	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	79.0
rs:WP_015110713	DNA topoisomerase I [Cyanobium gracile].	25.43	346	218	8	58	395	267	580	4e-12	79.0
rs:WP_037911842	DNA topoisomerase I [Streptomyces yeochonensis].	26.53	294	165	12	77	354	302	560	4e-12	79.0
rs:XP_002629150	DNA topoisomerase III [Blastomyces dermatitidis SLH14081].	25.95	316	180	10	73	369	296	576	4e-12	78.6
rs:WP_039662514	DNA topoisomerase I [Campylobacter subantarcticus].	24.94	393	229	16	77	450	255	600	4e-12	78.6
rs:WP_001953097	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	4e-12	79.0
rs:WP_015086777	DNA topoisomerase I [Helicobacter pylori].	24.77	432	253	17	41	450	218	599	4e-12	79.0
rs:WP_000681485	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	79.0
rs:WP_043646971	DNA topoisomerase I [Nocardia thailandica].	25.53	329	199	9	41	354	253	550	4e-12	79.0
rs:WP_015955427	DNA topoisomerase I [Cyanothece sp. PCC 7424].	23.81	357	231	9	41	387	249	574	4e-12	79.0
rs:WP_031372129	DNA topoisomerase I [Lysobacter antibioticus].	29.25	318	177	13	50	350	238	524	4e-12	79.0
rs:WP_037980021	DNA topoisomerase I [Streptomyces sp. TAA040].	26.63	338	186	14	35	354	267	560	4e-12	79.0
rs:WP_046027573	DNA topoisomerase I [Vibrio vulnificus].	25.51	345	214	10	40	377	253	561	4e-12	79.0
rs:WP_000681400	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	79.0
rs:WP_020921025	DNA topoisomerase 1 [Rhizobium etli].	24.72	441	265	16	47	452	230	638	4e-12	79.0
rs:WP_011424953	DNA topoisomerase I [Rhizobium etli].	24.72	441	265	16	47	452	230	638	4e-12	79.0
rs:WP_007611239	DNA topoisomerase I [Bradyrhizobium sp. WSM471].	23.58	424	259	14	61	452	244	634	4e-12	79.0
tr:A0A0A8H7G6_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.94	393	229	16	77	450	254	599	4e-12	78.6
rs:WP_009166274	DNA topoisomerase I [Lactobacillus florum].	23.83	407	254	14	61	452	257	622	4e-12	78.6
rs:WP_000681515	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	4e-12	79.0
rs:WP_033122603	DNA topoisomerase I [Helicobacter pylori].	24.30	395	235	15	74	450	251	599	4e-12	79.0
rs:WP_000681494	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	79.0
rs:WP_000681462	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	79.0
rs:WP_013096367	DNA topoisomerase I [Enterobacter cloacae].	24.93	381	233	15	77	446	284	622	4e-12	79.0
rs:WP_043915036	DNA topoisomerase I [Kitasatospora griseola].	25.85	294	167	12	77	354	300	558	4e-12	79.0
rs:WP_008730397	DNA topoisomerase I [Brachyspira hampsonii].	23.11	424	261	15	50	452	251	630	4e-12	78.6
rs:WP_021308843	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_044820000	DNA topoisomerase I [Bacteroides fragilis].	25.00	264	158	7	77	334	237	466	4e-12	79.0
rs:WP_002740254	DNA topoisomerase I [Leptospira borgpetersenii].	22.40	442	275	15	40	456	211	609	4e-12	78.6
rs:WP_001965050	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	4e-12	78.6
rs:WP_000681499	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_000681427	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_047877212	DNA topoisomerase I [Photobacterium aquae].	25.86	379	231	15	77	446	290	627	4e-12	79.0
rs:WP_016734024	DNA topoisomerase I [Rhizobium phaseoli].	24.83	439	267	15	47	452	230	638	4e-12	79.0
rs:WP_006634754	DNA topoisomerase I [Microcoleus vaginatus].	24.46	372	241	10	41	401	249	591	4e-12	79.0
rs:WP_024623694	DNA topoisomerase I [Lactobacillus fabifermentans].	23.63	402	238	16	77	457	284	637	4e-12	78.6
rs:WP_006915959	DNA topoisomerase I [Lactobacillus coleohominis].	25.49	408	237	17	65	452	266	626	4e-12	78.6
rs:WP_039083418	DNA topoisomerase I [Gallibacterium anatis].	25.07	375	240	12	77	446	290	628	4e-12	79.0
rs:WP_000681409	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	4e-12	78.6
rs:WP_018568916	DNA topoisomerase I [Streptomyces sp. PsTaAH-124].	26.62	293	166	11	77	354	299	557	4e-12	79.0
rs:WP_037894231	DNA topoisomerase I [Streptomyces sp. Tu 6176].	26.62	293	166	11	77	354	299	557	4e-12	79.0
rs:WP_030588325	DNA topoisomerase I [Streptomyces anulatus].	26.12	291	170	9	77	354	301	559	4e-12	79.0
rs:WP_001954546	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_000681483	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_004317201	MULTISPECIES: DNA topoisomerase I [Bacteroides].	25.00	312	191	8	36	334	201	482	4e-12	78.6
sp:TOP3B_ARATH	RecName: Full=DNA topoisomerase 3-beta; EC=5.99.1.2;	24.22	322	194	11	40	351	258	539	4e-12	79.0
rs:XP_003102480	hypothetical protein CRE_04022 [Caenorhabditis remanei].	23.68	473	287	19	12	457	232	657	4e-12	79.0
rs:WP_000681436	DNA topoisomerase I [Helicobacter pylori].	24.43	397	232	15	74	450	251	599	4e-12	78.6
rs:WP_001963288	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_042630303	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_033748728	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_001948369	DNA topoisomerase I [Helicobacter pylori].	24.87	394	234	14	74	450	251	599	4e-12	78.6
rs:WP_000681444	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	4e-12	78.6
rs:WP_020966639	DNA topoisomerase I [Chlamydia trachomatis].	23.13	428	258	16	47	449	241	622	4e-12	79.0
rs:WP_030524188	DNA topoisomerase I [Nocardia rhamnosiphila].	25.56	360	223	10	36	379	264	594	4e-12	79.0
rs:WP_047411545	DNA topoisomerase I [Herbiconiux sp. YR403].	26.89	357	195	15	30	356	247	567	4e-12	79.0
rs:WP_014440449	DNA topoisomerase I [Actinoplanes missouriensis].	26.89	383	223	15	47	409	266	611	4e-12	79.0
rs:WP_009104432	DNA topoisomerase I [Treponema sp. JC4].	22.90	428	264	15	46	452	233	615	4e-12	78.6
tr:A0A0D6ME44_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.33	300	173	10	66	350	254	523	4e-12	78.6
rs:WP_041208968	DNA topoisomerase I [Aeromonas jandaei].	24.58	419	260	14	49	452	259	636	4e-12	79.0
rs:WP_015645546	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_000681442	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	4e-12	78.6
rs:WP_015938306	DNA topoisomerase I [Arthrobacter chlorophenolicus].	25.28	356	223	12	42	380	254	583	4e-12	79.0
rs:WP_040155991	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_024751547	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_000681493	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_000681450	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_005675246	DNA topoisomerase I [Bacteroides caccae].	25.63	316	184	9	36	334	201	482	4e-12	78.6
rs:WP_009872811	DNA topoisomerase I [Chlamydia trachomatis].	23.13	428	258	16	47	449	241	622	4e-12	78.6
rs:WP_046073425	DNA topoisomerase I [Salinivibrio sp. KP-1].	25.59	379	232	15	77	446	290	627	4e-12	79.0
rs:WP_024850251	DNA topoisomerase I [Thiomicrospira kuenenii].	27.34	278	163	7	60	334	236	477	4e-12	78.6
rs:WP_000681498	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_000681476	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
sp:TOP1_HELPY	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_014456565	DNA topoisomerase I [Spirochaeta africana].	27.99	318	185	11	47	354	260	543	4e-12	78.6
rs:WP_006562565	DNA topoisomerase I [Oscillochloris trichoides].	26.61	357	209	9	47	378	231	559	4e-12	78.6
rs:WP_038866755	MULTISPECIES: DNA topoisomerase I [Vibrio].	26.25	320	191	10	77	386	291	575	4e-12	78.6
rs:WP_010324337	topoisomerase I [Marinobacterium stanieri].	23.53	391	246	14	69	446	281	631	4e-12	78.6
rs:WP_000681414	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	4e-12	78.6
rs:WP_000681519	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	4e-12	78.6
rs:WP_000681422	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_016194266	DNA topoisomerase I [Arcticibacter svalbardensis].	24.78	343	222	8	1	334	170	485	4e-12	78.6
rs:WP_014494702	DNA topoisomerase I [Bradyrhizobium japonicum].	23.88	423	259	13	61	452	244	634	4e-12	79.0
rs:WP_021015979	DNA topoisomerase I [Serratia sp. ATCC 39006].	24.68	393	252	13	61	446	267	622	4e-12	78.6
rs:WP_024875421	DNA topoisomerase I [Saccharomonospora sp. CNQ490].	25.82	395	243	13	66	439	296	661	4e-12	79.0
rs:WP_021740085	DNA topoisomerase I [Eubacterium ramulus].	25.06	423	262	13	48	454	227	610	4e-12	78.6
rs:WP_022342391	DNA topoisomerase [Roseburia sp. CAG:309].	25.40	252	153	7	207	454	6	226	4e-12	76.6
tr:D0TKZ0_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	312	191	8	36	334	211	492	4e-12	78.6
rs:WP_033582285	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_001943348	DNA topoisomerase I [Helicobacter pylori].	25.76	396	228	17	74	450	251	599	4e-12	78.6
rs:WP_017279968	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_000681526	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_042283444	DNA topoisomerase I [Citrobacter sedlakii].	25.27	376	238	12	77	446	284	622	4e-12	78.6
rs:WP_036898276	DNA topoisomerase I [Prevotella sp. S7 MS 2].	25.94	293	180	7	47	334	222	482	4e-12	78.6
rs:WP_035815296	DNA topoisomerase I, partial [Jiangella gansuensis].	28.25	315	186	13	77	379	301	587	4e-12	78.6
rs:WP_029567813	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_036836776	MULTISPECIES: DNA topoisomerase I [Actinobacteria].	24.92	329	201	10	41	354	271	568	4e-12	79.0
rs:WP_006955122	topoisomerase I [Idiomarina baltica].	24.88	426	253	16	48	452	261	640	4e-12	78.6
tr:H2Z240_CIOSA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.56	356	210	12	60	400	284	599	4e-12	78.6
tr:A0A081CCC8_CANAR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.37	339	202	12	39	363	272	573	4e-12	79.0
rs:WP_033589834	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_001956342	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	4e-12	78.6
rs:WP_039358543	DNA topoisomerase I [Pectobacterium carotovorum].	25.06	399	243	13	61	446	268	623	4e-12	78.6
rs:WP_003578623	DNA topoisomerase I [Rhizobium leguminosarum].	25.06	419	253	13	67	452	248	638	4e-12	78.6
rs:WP_032532316	hypothetical protein, partial [Streptococcus suis].	24.79	363	225	13	47	396	250	577	4e-12	78.2
rs:WP_041434247	DNA topoisomerase I [Thermocrinis albus].	24.26	338	208	9	47	377	217	513	4e-12	78.2
rs:WP_016581610	topoisomerase I, partial [Yersinia pestis].	24.47	380	236	13	77	446	290	628	4e-12	78.6
gp:CP011403_722	DNA topoisomerase I [Lactobacillus salivarius str. Ren]	23.18	440	278	14	31	452	180	577	5e-12	78.6
rs:WP_033786383	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	5e-12	78.6
rs:WP_000681471	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	5e-12	78.6
rs:WP_000681454	DNA topoisomerase I [Helicobacter pylori].	25.76	396	228	17	74	450	251	599	5e-12	78.6
rs:WP_019485982	hypothetical protein, partial [Pseudomonas aeruginosa].	31.34	134	83	3	321	454	1	125	5e-12	74.3
rs:WP_030599765	DNA topoisomerase I [Streptomyces fulvoviolaceus].	26.62	293	166	11	77	354	299	557	5e-12	78.6
tr:A0A0A5LGL4_AERHY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.05	420	261	14	49	452	259	636	5e-12	78.6
rs:WP_045628896	DNA topoisomerase I [Vibrio vulnificus].	26.09	345	212	10	40	377	253	561	5e-12	78.6
rs:WP_015583347	DNA topoisomerase I [Propionibacterium avidum].	26.05	380	223	16	35	388	243	590	5e-12	78.6
rs:WP_033743595	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	5e-12	78.6
rs:WP_026938559	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	5e-12	78.6
rs:WP_016548180	DNA topoisomerase I [Leptospira fainei].	24.75	404	232	13	74	449	249	608	5e-12	78.6
rs:WP_044257728	DNA topoisomerase I [Citrobacter sp. JT3].	25.53	380	232	14	77	446	284	622	5e-12	78.6
rs:WP_029910794	DNA topoisomerase I [Hydrogenovibrio marinus].	26.15	283	160	8	60	334	236	477	5e-12	78.6
tr:A0A068WM85_ECHGR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.74	477	250	18	39	450	257	689	5e-12	79.0
tr:K0TAA4_THAOC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJK74455.1}; Flags: Fragment;	26.16	302	172	9	47	340	366	624	5e-12	78.6
rs:WP_032821507	topoisomerase I, partial [Oenococcus oeni].	32.67	150	98	2	250	397	1	149	5e-12	75.5
rs:WP_036965640	DNA topoisomerase I [Promicromonospora kroppenstedtii].	28.16	348	197	14	35	356	243	563	5e-12	78.6
rs:WP_028959465	DNA topoisomerase I [Streptomyces sp. UNC401CLCol].	26.62	293	166	11	77	354	299	557	5e-12	78.6
rs:WP_047016523	DNA topoisomerase I [Streptomyces sp. CNQ-509].	26.81	317	189	11	47	351	269	554	5e-12	78.6
rs:WP_012660909	DNA topoisomerase I [Campylobacter lari].	24.81	395	233	16	74	450	251	599	5e-12	78.6
rs:WP_002725647	DNA topoisomerase I [Leptospira borgpetersenii].	22.40	442	275	15	40	456	211	609	5e-12	78.2
rs:WP_001961309	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	5e-12	78.6
rs:WP_000681500	DNA topoisomerase I [Helicobacter pylori].	24.71	429	257	16	41	450	218	599	5e-12	78.6
rs:WP_000681496	DNA topoisomerase I [Helicobacter pylori].	24.94	393	235	14	74	450	251	599	5e-12	78.6
rs:WP_000681484	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	5e-12	78.6
rs:WP_011069349	topoisomerase I [Shigella flexneri].	25.53	376	237	12	77	446	284	622	5e-12	78.6
rs:WP_039549548	DNA topoisomerase I [Pectobacterium carotovorum].	25.06	399	243	13	61	446	268	623	5e-12	78.6
tr:A0A0E9MBV0_9PROT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAO34943.1};	24.34	419	253	14	56	452	243	619	5e-12	78.6
rs:WP_030087088	DNA topoisomerase I [Streptomyces baarnensis].	26.64	289	171	10	77	354	301	559	5e-12	78.6
rs:WP_029406632	DNA topoisomerase I [Thiomicrospira sp. Milos-T2].	26.80	291	174	7	47	334	223	477	5e-12	78.6
rs:WP_019527427	DNA topoisomerase I [Streptomyces sp. FxanaD5].	26.62	293	166	11	77	354	299	557	5e-12	78.6
rs:WP_028702223	DNA topoisomerase I [Propionibacterium jensenii].	24.53	375	223	11	35	379	238	582	5e-12	78.6
rs:WP_038281690	DNA topoisomerase I [[Clostridium] celerecrescens].	23.65	427	269	13	48	457	230	616	5e-12	78.6
rs:WP_012483459	DNA topoisomerase I [Rhizobium etli].	24.83	439	267	15	47	452	230	638	5e-12	78.6
rs:WP_004668461	DNA topoisomerase I [Rhizobium etli].	24.83	439	267	15	47	452	230	638	5e-12	78.6
rs:WP_017201450	DNA topoisomerase I [Microbacterium barkeri].	28.66	335	191	14	41	356	247	552	5e-12	78.6
rs:XP_012523363	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Monomorium pharaonis].	24.58	415	249	14	60	449	278	653	5e-12	78.6
gpu:CP011497_3232	DNA topoisomerase I [Streptomyces incarnatus]	26.62	293	166	11	77	354	299	557	5e-12	78.6
rs:WP_000681509	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	5e-12	78.6
rs:WP_022043262	DNA topoisomerase [Bacteroides caccae CAG:21].	25.63	316	184	9	36	334	201	482	5e-12	78.6
rs:WP_008617440	DNA topoisomerase I [Paraprevotella clara].	24.92	297	192	6	40	334	214	481	5e-12	78.6
rs:WP_033609574	DNA topoisomerase I [Helicobacter pylori].	24.75	396	232	16	74	450	251	599	5e-12	78.6
rs:WP_013001771	DNA topoisomerase I [Streptomyces scabiei].	26.74	288	172	9	77	354	299	557	5e-12	78.6
rs:WP_042631886	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	5e-12	78.6
rs:WP_021186885	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	5e-12	78.6
rs:WP_018651935	topoisomerase I [Actinobacillus capsulatus].	24.28	416	252	16	47	446	261	629	5e-12	78.6
tr:U5EHU8_NOCAS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.92	329	201	10	41	354	253	550	5e-12	78.6
rs:WP_000681446	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	5e-12	78.6
rs:WP_046863367	DNA topoisomerase I [Microvirga sp. JC119].	24.55	448	251	18	43	452	236	634	5e-12	78.6
rs:WP_024025561	topoisomerase I [Marinomonas profundimaris].	24.10	361	226	11	36	384	253	577	5e-12	78.6
rs:WP_000681435	DNA topoisomerase I [Helicobacter pylori].	25.76	396	228	17	74	450	251	599	5e-12	78.6
rs:WP_021172441	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	5e-12	78.6
tr:H8H1G5_DEIGI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.74	344	208	10	42	377	246	553	5e-12	78.6
rs:WP_006190095	DNA topoisomerase I [Treponema vincentii].	23.40	423	262	13	49	452	241	620	5e-12	78.6
tr:M0T393_MUSAM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.84	464	286	15	24	452	255	681	5e-12	78.6
rs:WP_043000535	MULTISPECIES: DNA topoisomerase I [Gammaproteobacteria].	25.53	380	232	14	77	446	284	622	5e-12	78.6
rs:WP_031816604	DNA topoisomerase I [Vibrio parahaemolyticus].	24.60	378	237	13	77	446	214	551	5e-12	78.6
rs:WP_030633085	DNA topoisomerase I [Streptomyces albus].	26.64	289	171	10	77	354	301	559	5e-12	78.6
rs:WP_047389132	DNA topoisomerase I, partial [Firmicutes bacterium ZOR0006].	24.16	418	255	12	48	449	226	597	5e-12	78.6
rs:WP_030801500	DNA topoisomerase I [Streptomyces sp. NRRL S-337].	27.34	289	169	10	77	354	301	559	5e-12	78.6
rs:WP_022040214	DNA topoisomerase [Bacteroides sp. CAG:702].	27.82	266	148	8	77	334	250	479	5e-12	78.6
rs:WP_000681430	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	5e-12	78.6
rs:WP_039091272	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	5e-12	78.6
rs:WP_000681410	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	5e-12	78.6
rs:WP_000681407	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	5e-12	78.6
rs:WP_020359163	DNA topoisomerase I [Chlamydia psittaci].	23.15	445	269	17	28	449	228	622	5e-12	78.6
rs:WP_019036094	DNA topoisomerase I [Prevotella amnii].	25.09	267	160	6	77	334	253	488	5e-12	78.6
rs:XP_009516746	hypothetical protein PHYSODRAFT_470148 [Phytophthora sojae].	24.07	349	215	11	39	373	264	576	5e-12	78.6
rs:WP_012379792	DNA topoisomerase I [Streptomyces griseus].	26.55	290	170	10	77	354	301	559	5e-12	78.6
rs:WP_003999165	DNA topoisomerase [Streptomyces viridochromogenes].	26.62	293	166	11	77	354	299	557	5e-12	78.6
rs:WP_002733581	DNA topoisomerase I [Leptospira borgpetersenii].	22.40	442	275	15	40	456	211	609	5e-12	78.2
rs:WP_029834336	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	25.13	378	235	13	77	446	220	557	5e-12	78.6
rs:WP_027161474	DNA topoisomerase I [Mesorhizobium sp. WSM1293].	25.94	451	256	21	41	452	224	635	5e-12	78.6
rs:WP_001950177	DNA topoisomerase I [Helicobacter pylori].	25.76	396	228	17	74	450	251	599	5e-12	78.6
rs:WP_000681468	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	5e-12	78.6
rs:WP_000681453	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	5e-12	78.6
rs:WP_000681402	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	5e-12	78.6
rs:WP_014915357	topoisomerase I [Pectobacterium carotovorum].	25.06	399	243	13	61	446	268	623	5e-12	78.6
tr:I7KUW7_9CLOT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.03	362	216	9	36	377	213	535	5e-12	78.2
rs:WP_043135968	DNA topoisomerase I [Aeromonas salmonicida].	25.00	420	257	16	49	452	259	636	5e-12	78.6
tr:D3SM80_THEAH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00003390}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.26	338	208	9	47	377	218	514	5e-12	78.2
rs:WP_000681406	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	5e-12	78.6
rs:WP_034998089	DNA topoisomerase I [Lactobacillus salivarius].	23.67	414	258	13	55	452	248	619	5e-12	78.6
rs:WP_025882636	DNA topoisomerase I [Porphyromonas uenonis].	27.59	261	154	7	77	334	253	481	5e-12	78.6
rs:WP_000681412	DNA topoisomerase I [Helicobacter pylori].	24.94	393	235	14	74	450	251	599	5e-12	78.6
rs:XP_012523360	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Monomorium pharaonis].	24.58	415	249	14	60	449	293	668	5e-12	78.6
rs:WP_012848405	MULTISPECIES: topoisomerase I [Edwardsiella].	25.00	320	196	9	77	386	284	569	5e-12	78.6
tr:A0A0A2LBI9_PENIT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.68	342	194	8	41	359	261	558	5e-12	78.2
rs:WP_019873940	hypothetical protein [Sporichthya polymorpha].	27.19	331	185	13	77	387	307	601	5e-12	78.6
rs:XP_010750977	PREDICTED: DNA topoisomerase 3-beta-1 [Larimichthys crocea].	22.98	409	244	13	40	421	263	627	5e-12	78.2
rs:WP_031140379	MULTISPECIES: DNA topoisomerase I [Streptomyces].	26.28	293	167	11	77	354	299	557	5e-12	78.6
tr:S7J7E5_CHLPS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.15	445	269	17	28	449	221	615	5e-12	78.6
rs:WP_003703765	DNA topoisomerase I [Lactobacillus salivarius].	23.18	440	278	14	31	452	222	619	5e-12	78.2
rs:WP_031939868	DNA topoisomerase I [Rhodococcus defluvii].	25.69	327	201	10	41	354	265	562	5e-12	78.6
rs:WP_001972760	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	5e-12	78.6
gpu:CP011211_1039	topoisomerase protein [Candidatus Saccharibacteria bacterium GW2011_GWC2_44_17]	27.80	259	148	7	77	333	252	473	5e-12	78.6
tr:M2UQN7_COCH5	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.10	310	179	10	39	339	259	530	5e-12	78.2
rs:WP_043265431	DNA topoisomerase I [Streptomyces sp. CT34].	27.34	289	169	10	77	354	300	558	5e-12	78.6
rs:WP_000681455	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	5e-12	78.6
rs:WP_000681451	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	5e-12	78.6
rs:WP_027836252	DNA topoisomerase I [Mastigocoleus testarum].	24.19	430	271	13	47	452	231	629	5e-12	78.6
rs:WP_046552789	DNA topoisomerase I [Arsukibacterium sp. MJ3].	23.75	379	241	11	77	446	280	619	5e-12	78.6
rs:WP_042029403	DNA topoisomerase I [Aeromonas jandaei].	24.58	419	260	14	49	452	259	636	5e-12	78.6
rs:WP_009730737	DNA topoisomerase III [Streptococcus sp. F0441].	23.73	354	222	12	44	385	245	562	5e-12	78.2
rs:WP_021108253	MULTISPECIES: DNA topoisomerase I [Propionibacterium].	24.64	414	242	17	35	422	243	612	5e-12	78.6
rs:WP_045730466	DNA topoisomerase I [Arthrobacter chlorophenolicus].	25.28	356	223	12	42	380	254	583	5e-12	78.6
rs:WP_002208130	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	5e-12	78.6
rs:WP_028155046	DNA topoisomerase I [Bradyrhizobium japonicum].	23.88	423	259	13	61	452	244	634	5e-12	78.6
rs:WP_047964257	DNA topoisomerase I [Xenorhabdus khoisanae].	26.15	390	234	17	77	452	284	633	5e-12	78.6
rs:WP_039821720	DNA topoisomerase I [Nocardia testacea].	25.56	360	223	10	36	379	264	594	5e-12	78.6
rs:WP_021310272	DNA topoisomerase I [Helicobacter pylori].	25.31	399	226	17	74	450	251	599	5e-12	78.2
gpu:CP011268_787	DNA topoisomerase 1 [candidate division SR1 bacterium Aalborg_AAW-1]	25.82	275	163	7	77	340	275	519	5e-12	78.6
tr:K1RY66_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EKC50268.1}; Flags: Fragment;	27.57	272	151	11	48	293	226	477	5e-12	77.8
rs:XP_011199748	PREDICTED: DNA topoisomerase 3-alpha [Bactrocera dorsalis].	23.89	452	270	14	35	451	276	688	5e-12	78.6
rs:WP_003013852	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	5e-12	78.2
rs:WP_000681449	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	5e-12	78.2
rs:WP_000681399	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	5e-12	78.2
rs:WP_011715198	DNA topoisomerase I [Magnetococcus marinus].	24.32	444	270	14	43	454	230	639	5e-12	78.6
rs:WP_014553125	DNA topoisomerase I [Halanaerobium praevalens].	24.07	428	263	13	47	456	228	611	5e-12	78.2
tr:W1DTU0_KLEPN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CDL12871.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDL12871.1};	41.94	93	54	0	293	385	1	93	5e-12	73.9
rs:WP_039085178	DNA topoisomerase I [Helicobacter pylori].	25.76	396	228	17	74	450	251	599	5e-12	78.2
rs:WP_024114980	DNA topoisomerase I [Helicobacter pylori].	24.94	393	235	14	74	450	251	599	5e-12	78.2
rs:WP_011578289	DNA topoisomerase I [Helicobacter acinonychis].	25.25	396	230	17	74	450	251	599	5e-12	78.2
rs:WP_039496180	DNA topoisomerase I [Pectobacterium carotovorum].	25.06	399	243	13	61	446	268	623	5e-12	78.6
rs:WP_036039292	DNA topoisomerase I [Bradyrhizobium yuanmingense].	24.11	423	258	12	61	452	244	634	5e-12	78.6
rs:WP_029963009	hypothetical protein, partial [Aerophobetes bacterium SCGC AAA255-F10].	24.15	439	264	17	36	452	133	524	5e-12	78.2
rs:WP_020122616	DNA topoisomerase I [Streptomyces canus].	26.62	293	166	11	77	354	299	557	5e-12	78.6
rs:WP_047035564	DNA topoisomerase I [Lactobacillus salivarius].	23.18	440	278	14	31	452	222	619	5e-12	78.2
rs:WP_003967422	DNA topoisomerase I [Streptomyces sp. ACT-1].	26.55	290	170	10	77	354	301	559	5e-12	78.6
tr:W4YW04_STRPU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.72	346	212	11	40	377	262	570	5e-12	78.2
rs:WP_001944744	DNA topoisomerase I [Helicobacter pylori].	24.75	396	232	16	74	450	251	599	5e-12	78.2
rs:WP_000681507	DNA topoisomerase I [Helicobacter pylori].	25.76	396	228	17	74	450	251	599	5e-12	78.2
rs:WP_000681506	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	5e-12	78.2
rs:WP_027559642	MULTISPECIES: DNA topoisomerase I [Bradyrhizobium].	24.11	423	258	12	61	452	244	634	5e-12	78.6
rs:WP_009369974	DNA topoisomerase I [Megasphaera genomosp. type_1].	25.00	396	232	15	77	452	313	663	5e-12	78.2
rs:WP_027052032	DNA topoisomerase I [Mesorhizobium loti].	26.02	442	255	19	47	452	230	635	5e-12	78.6
rs:XP_003662864	hypothetical protein MYCTH_2303986 [Myceliophthora thermophila ATCC 42464].	25.61	328	196	11	18	334	233	523	5e-12	78.2
rs:WP_018259862	DNA topoisomerase I [Methylobacterium sp. WSM2598].	26.21	454	236	19	43	452	236	634	5e-12	78.6
rs:WP_000681522	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	5e-12	78.2
rs:WP_000681423	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	5e-12	78.2
rs:WP_001940876	DNA topoisomerase I [Helicobacter pylori].	25.76	396	228	17	74	450	251	599	5e-12	78.2
rs:WP_001918750	DNA topoisomerase I [Helicobacter pylori].	24.87	394	234	14	74	450	251	599	5e-12	78.2
tr:L8JIZ1_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.68	401	235	17	62	446	240	597	5e-12	78.6
rs:WP_029805460	DNA topoisomerase I [Vibrio parahaemolyticus].	25.13	378	235	13	77	446	291	628	5e-12	78.6
rs:WP_025794756	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	5e-12	78.6
rs:WP_044883917	DNA topoisomerase I [Frankia sp. CpI1-S].	26.54	324	198	10	77	387	391	687	5e-12	78.6
rs:WP_038972448	DNA topoisomerase I [Bradyrhizobium sp. CCBAU 15635].	24.64	414	249	12	70	452	253	634	5e-12	78.6
rs:WP_038950308	DNA topoisomerase I [Bradyrhizobium sp. CCBAU 15544].	24.64	414	249	12	70	452	253	634	5e-12	78.6
rs:WP_008442944	DNA topoisomerase I [Halorubrum californiense].	24.51	408	235	13	86	454	297	670	5e-12	78.6
rs:WP_040516161	DNA topoisomerase I [Gordonia amarae].	26.89	305	176	11	66	354	290	563	6e-12	78.6
rs:WP_014002039	DNA topoisomerase I [Acidithiobacillus caldus].	27.23	426	232	20	59	454	245	622	6e-12	78.6
rs:WP_025422046	DNA topoisomerase I [Sodalis praecaptivus].	25.19	393	234	15	77	452	281	630	6e-12	78.6
rs:WP_000681513	DNA topoisomerase I [Helicobacter pylori].	25.76	396	228	17	74	450	251	599	6e-12	78.2
rs:WP_000681505	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	6e-12	78.2
rs:WP_000681465	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	6e-12	78.2
rs:WP_035757834	DNA topoisomerase I [Arthrobacter albus].	27.92	308	171	12	66	356	283	556	6e-12	78.6
rs:WP_001916775	DNA topoisomerase I [Helicobacter pylori].	24.94	393	235	14	74	450	251	599	6e-12	78.2
rs:WP_000681431	DNA topoisomerase I [Helicobacter pylori].	24.94	393	235	14	74	450	251	599	6e-12	78.2
rs:WP_000681421	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	6e-12	78.2
tr:U7K4F4_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.64	414	242	17	35	422	281	650	6e-12	78.6
tr:F7QV08_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.67	414	258	13	55	452	206	577	6e-12	78.2
rs:WP_013320268	DNA topoisomerase I [Cyanothece sp. PCC 7822].	23.81	357	231	9	41	387	249	574	6e-12	78.6
rs:WP_000681528	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	6e-12	78.2
rs:WP_000681470	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	6e-12	78.2
rs:WP_042744564	topoisomerase I, partial [Oenococcus oeni].	29.41	187	111	6	284	454	1	182	6e-12	75.1
rs:WP_013531916	DNA topoisomerase I [Mesorhizobium ciceri].	25.94	451	256	21	41	452	224	635	6e-12	78.6
rs:WP_016597622	topoisomerase I, partial [Yersinia pestis].	24.93	381	233	14	77	446	154	492	6e-12	78.2
rs:WP_012334082	DNA topoisomerase I [Methylobacterium sp. 4-46].	26.21	454	236	19	43	452	236	634	6e-12	78.6
rs:WP_002207369	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	6e-12	78.2
rs:WP_000681480	DNA topoisomerase I [Helicobacter pylori].	24.18	397	233	15	74	450	251	599	6e-12	78.2
rs:WP_033200472	hypothetical protein, partial [Pseudonocardia sp. P1].	25.00	324	201	9	41	351	273	567	6e-12	78.6
rs:WP_028152767	DNA topoisomerase I [Bradyrhizobium japonicum].	23.64	423	260	13	61	452	244	634	6e-12	78.6
rs:WP_024304701	DNA topoisomerase I [Cloacimonetes bacterium SCGC AAA252-N11].	23.53	425	249	16	48	452	236	604	6e-12	78.2
rs:WP_043804823	DNA topoisomerase I, partial [Deinococcus gobiensis].	26.74	344	208	10	42	377	246	553	6e-12	77.8
rs:WP_010307984	DNA topoisomerase I [Saccharopolyspora spinosa].	24.88	402	235	14	36	411	251	611	6e-12	78.6
rs:NP_001031463	DNA topoisomerase, type IA, core [Arabidopsis thaliana].	24.84	322	192	11	40	351	231	512	6e-12	78.2
rs:WP_013758112	DNA topoisomerase I [Treponema brennaborense].	22.50	440	271	14	36	452	230	622	6e-12	78.2
rs:WP_038823909	DNA topoisomerase I [Yersinia pseudotuberculosis].	24.47	380	236	13	77	446	290	628	6e-12	78.2
rs:WP_030846072	DNA topoisomerase I [Streptomyces sp. NRRL S-475].	26.28	293	167	11	77	354	299	557	6e-12	78.6
rs:WP_025326222	DNA topoisomerase I [Aeromonas hydrophila].	24.05	420	261	13	49	452	259	636	6e-12	78.2
rs:WP_023591798	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	6e-12	78.2
rs:WP_014397849	DNA topoisomerase I [Corallococcus coralloides].	24.06	453	260	15	41	452	298	707	6e-12	78.2
rs:WP_031115960	DNA topoisomerase I [Streptomyces sp. NRRL WC-3641].	26.28	293	167	11	77	354	299	557	6e-12	78.6
rs:WP_016587519	topoisomerase I, partial [Yersinia pestis].	24.93	381	233	14	77	446	197	535	6e-12	78.2
rs:WP_032825422	topoisomerase I, partial [Oenococcus oeni].	30.23	172	107	6	56	221	8	172	6e-12	74.3
rs:WP_033268914	DNA topoisomerase I [Streptomyces lydicus].	26.99	289	170	10	77	354	300	558	6e-12	78.6
tr:W8JMV0_9CHLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.83	407	242	17	66	449	264	625	6e-12	78.2
tr:M3NPB4_HELPX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.76	396	228	17	74	450	251	599	6e-12	78.2
rs:WP_034448315	DNA topoisomerase I [Cloacimonetes bacterium SCGC AAA252-E13].	23.53	425	249	16	48	452	236	604	6e-12	78.2
rs:WP_029608746	DNA topoisomerase I [Mycoplasma simbae].	26.86	376	213	14	92	452	272	600	6e-12	78.2
rs:WP_023030006	DNA topoisomerase I [Corynebacterium sp. KPL1818].	24.65	361	215	12	47	384	266	592	6e-12	78.6
rs:WP_000681439	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	6e-12	78.2
rs:WP_000681404	DNA topoisomerase I [Helicobacter pylori].	24.49	396	233	16	74	450	251	599	6e-12	78.2
rs:WP_028025214	DNA topoisomerase I [Enterovibrio calviensis].	25.80	376	235	13	77	446	290	627	6e-12	78.2
rs:WP_039702831	hypothetical protein, partial [marine actinobacterium MedAcidi-G2A].	26.24	343	199	11	69	394	294	599	6e-12	78.2
rs:WP_020840336	topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	6e-12	78.2
rs:WP_023587330	DNA topoisomerase I [Streptomyces thermolilacinus].	26.28	293	167	11	77	354	299	557	6e-12	78.6
tr:C2EF62_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.18	440	278	14	31	452	234	631	6e-12	78.2
rs:WP_031830982	hypothetical protein, partial [Vibrio parahaemolyticus].	31.72	145	93	4	35	176	224	365	6e-12	77.0
rs:WP_030677717	DNA topoisomerase I [Streptomyces rimosus].	26.64	289	171	10	77	354	301	559	6e-12	78.6
rs:WP_043084341	DNA topoisomerase I [Pluralibacter gergoviae].	25.37	339	211	9	19	354	231	530	6e-12	78.2
rs:WP_040035700	DNA topoisomerase I [Pectobacterium carotovorum].	25.06	399	243	13	61	446	268	623	6e-12	78.2
rs:WP_010044211	DNA topoisomerase I [Streptomyces chartreusis].	26.28	293	167	11	77	354	299	557	6e-12	78.2
rs:WP_028656482	DNA topoisomerase I [Nocardioides sp. J54].	25.54	368	228	12	25	377	238	574	6e-12	78.2
rs:WP_019433970	DNA topoisomerase I [Streptomyces sp. AA0539].	26.64	289	171	10	77	354	300	558	6e-12	78.6
rs:WP_029562680	DNA topoisomerase I, partial [Yersinia pestis].	24.47	380	236	13	77	446	278	616	6e-12	78.2
rs:WP_028143943	MULTISPECIES: DNA topoisomerase I [Bradyrhizobium].	24.64	414	249	12	70	452	253	634	6e-12	78.2
rs:WP_045688840	DNA topoisomerase I [Hymenobacter sp. AT01-02].	26.80	291	182	6	47	334	220	482	6e-12	78.2
rs:WP_007236454	topoisomerase I [marine gamma proteobacterium HTCC2080].	26.84	313	188	10	48	354	264	541	6e-12	78.2
rs:XP_816014	DNA topoisomerase III [Trypanosoma cruzi strain CL Brener].	24.85	342	206	9	47	380	269	567	6e-12	78.2
rs:WP_038825724	DNA topoisomerase I [Yersinia pseudotuberculosis].	24.47	380	236	13	77	446	290	628	6e-12	78.2
rs:WP_003706174	DNA topoisomerase I [Lactobacillus salivarius].	23.67	414	258	13	55	452	248	619	6e-12	78.2
tr:E3EPR8_BIFBS	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ADO52605.1};	29.10	244	143	8	221	446	40	271	6e-12	77.0
tr:G7GWG8_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.89	305	176	11	66	354	272	545	6e-12	78.6
rs:WP_025077717	DNA topoisomerase I [Prevotella fusca].	23.97	267	163	6	77	334	252	487	6e-12	78.2
rs:WP_001957767	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	6e-12	78.2
rs:WP_000596183	hypothetical protein, partial [Escherichia coli].	32.85	137	82	3	311	443	4	134	6e-12	74.7
rs:WP_004331586	DNA topoisomerase I [Porphyromonas asaccharolytica].	28.41	264	148	8	77	334	253	481	6e-12	78.2
rs:WP_014937682	DNA topoisomerase I [Riemerella anatipestifer].	28.42	285	163	9	77	352	248	500	6e-12	78.2
rs:WP_011150808	topoisomerase I [Vibrio vulnificus].	25.51	345	214	10	40	377	253	561	6e-12	78.2
rs:WP_015178581	DNA topoisomerase I [Oscillatoria nigro-viridis].	24.93	373	238	11	41	401	249	591	6e-12	78.2
rs:WP_038312524	DNA topoisomerase I [bacterium YEK0313].	25.00	468	261	18	29	452	220	641	6e-12	78.2
rs:WP_034265900	DNA topoisomerase I, partial [Aminiphilus circumscriptus].	24.88	426	250	14	54	457	233	610	6e-12	78.2
tr:M5YMY3_HELPX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	396	231	16	74	450	251	599	6e-12	78.2
rs:WP_011670006	DNA topoisomerase I [Leptospira borgpetersenii].	22.35	443	275	15	40	456	211	610	6e-12	77.8
rs:WP_046260314	DNA topoisomerase I [Streptomyces sp. WM6386].	26.28	293	167	11	77	354	299	557	6e-12	78.2
rs:WP_013969129	DNA topoisomerase I [Treponema caldarium].	23.53	408	249	15	65	452	253	617	6e-12	78.2
rs:WP_014582537	DNA topoisomerase I [Mycoplasma hyorhinis].	22.48	387	231	9	83	450	261	597	6e-12	77.8
tr:A0A0B8PCN3_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.41	381	234	13	77	446	290	627	6e-12	78.2
rs:WP_030378629	MULTISPECIES: DNA topoisomerase I [Streptomyces].	26.62	293	166	11	77	354	299	557	6e-12	78.2
rs:WP_043036435	DNA topoisomerase [Streptococcus equi].	25.39	319	198	12	74	385	274	559	6e-12	77.8
rs:WP_009318380	DNA topoisomerase I [Tannerella sp. 6_1_58FAA_CT1].	25.67	261	160	6	77	334	253	482	6e-12	78.2
tr:A0A087GIK5_ARAAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.47	425	251	13	65	450	695	1088	6e-12	78.6
rs:WP_039171518	DNA topoisomerase I [Gallibacterium genomosp. 1].	24.80	375	241	12	77	446	290	628	6e-12	78.2
rs:WP_040802949	hypothetical protein, partial [Nocardia concava].	25.44	338	205	11	35	356	268	574	6e-12	78.2
rs:WP_018352275	hypothetical protein [Longispora albida].	25.97	362	218	12	42	385	250	579	6e-12	78.2
tr:U9SKB6_RHIID	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ERZ96388.1}; Flags: Fragment;	22.47	365	236	10	57	409	277	606	6e-12	78.6
rs:WP_034983386	DNA topoisomerase I [Lactobacillus salivarius].	23.67	414	258	13	55	452	248	619	6e-12	78.2
rs:WP_030199619	DNA topoisomerase I [Streptomyces sp. NRRL S-87].	26.96	293	165	11	77	354	299	557	6e-12	78.2
rs:WP_039316996	DNA topoisomerase I [Clostridium baratii].	22.77	426	267	13	48	454	225	607	6e-12	78.2
rs:WP_039082230	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	6e-12	78.2
rs:WP_000681458	DNA topoisomerase I [Helicobacter pylori].	24.94	393	235	14	74	450	251	599	6e-12	78.2
tr:A0A022LL56_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.96	366	206	12	47	387	272	597	6e-12	78.2
rs:WP_034459248	DNA topoisomerase I [Bartonella koehlerae].	26.42	424	239	19	67	452	248	636	6e-12	78.2
rs:WP_021662118	DNA topoisomerase I [Porphyromonas gingivalis].	27.88	269	152	8	77	338	248	481	6e-12	78.2
tr:A0A067S9L9_9AGAR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDR67536.1};	24.43	397	233	15	39	408	259	615	6e-12	77.8
rs:WP_000681475	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	6e-12	78.2
rs:WP_036798385	DNA topoisomerase I [Photobacterium sp. AK15].	26.68	401	235	17	62	446	270	627	6e-12	78.2
tr:A0A087GIK7_ARAAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.85	436	262	13	54	450	685	1089	6e-12	78.6
rs:WP_016365764	DNA topoisomerase I, partial [Lactobacillus paracasei].	25.08	295	182	8	166	452	75	338	6e-12	77.4
tr:D5EXD2_PRER2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.22	286	164	7	77	345	252	507	6e-12	78.2
rs:WP_013549702	DNA topoisomerase I [Cellulophaga algicola].	27.08	288	167	10	54	334	227	478	6e-12	78.2
tr:U7J6P3_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.26	384	221	16	35	388	281	628	6e-12	78.2
rs:WP_022383953	DNA topoisomerase [Bacteroides sp. CAG:462].	28.08	260	154	8	77	334	252	480	6e-12	78.2
tr:A0A0A1PJ72_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	468	261	18	29	452	222	643	6e-12	78.2
rs:WP_016599731	topoisomerase I, partial [Yersinia pestis].	24.93	381	233	14	77	446	253	591	6e-12	78.2
rs:WP_039709549	DNA topoisomerase I [Actinobacillus pleuropneumoniae].	25.06	411	255	16	47	446	261	629	6e-12	78.2
rs:WP_016261235	topoisomerase I, partial [Yersinia pestis].	24.47	380	236	13	77	446	266	604	6e-12	78.2
rs:WP_023526886	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	6e-12	78.2
rs:WP_009144254	topoisomerase I [Succinatimonas hippei].	25.80	376	221	11	65	425	262	594	6e-12	78.2
rs:WP_042001259	DNA topoisomerase I [Capnocytophaga canimorsus].	25.86	290	178	8	56	340	228	485	6e-12	78.2
rs:WP_016679553	topoisomerase I, partial [Yersinia pestis].	24.47	380	236	13	77	446	261	599	6e-12	78.2
rs:WP_023847008	DNA topoisomerase I [Porphyromonas gingivalis].	27.88	269	152	8	77	338	248	481	6e-12	78.2
rs:WP_011475885	DNA topoisomerase I [Lactobacillus salivarius].	23.18	440	278	14	31	452	222	619	6e-12	78.2
rs:WP_038230196	topoisomerase I [Xylella fastidiosa].	70.21	47	14	0	260	306	1	47	6e-12	72.4
rs:WP_038500965	DNA topoisomerase I [Chlamydia avium].	23.83	407	242	17	66	449	261	622	6e-12	78.2
rs:WP_015085368	DNA topoisomerase I [Helicobacter pylori].	24.43	397	232	14	74	450	251	599	6e-12	78.2
rs:WP_021744852	DNA topoisomerase III [Leptotrichia sp. oral taxon 879].	23.31	429	276	15	36	450	234	623	6e-12	78.2
rs:WP_033150319	DNA topoisomerase I [Prevotella sp. RM4].	26.22	286	164	7	77	345	252	507	7e-12	78.2
rs:WP_006142055	DNA topoisomerase I [Streptomyces griseoaurantiacus].	26.96	293	165	11	77	354	299	557	7e-12	78.2
rs:WP_030015206	DNA topoisomerase I [Curtobacterium sp. S6].	24.65	357	221	10	42	379	261	588	7e-12	78.2
rs:WP_014462334	topoisomerase I [Yersinia pestis].	24.47	380	236	13	77	446	226	564	7e-12	78.2
rs:WP_012105105	topoisomerase I [Yersinia pseudotuberculosis].	24.47	380	236	13	77	446	290	628	7e-12	78.2
rs:WP_039439117	DNA topoisomerase I [Porphyromonas gulae].	27.88	269	152	8	77	338	248	481	7e-12	78.2
rs:WP_048286686	DNA topoisomerase I [Pluralibacter gergoviae].	25.37	339	211	9	19	354	231	530	7e-12	78.2
rs:WP_007356210	MULTISPECIES: DNA topoisomerase I [Kamptonema].	24.52	310	198	7	41	344	256	535	7e-12	78.2
rs:WP_034388160	DNA topoisomerase I [Deinococcus sp. YIM 77859].	25.39	323	191	11	38	344	248	536	7e-12	78.2
rs:WP_003710032	DNA topoisomerase I [Lactobacillus salivarius].	23.67	414	258	13	55	452	248	619	7e-12	78.2
rs:WP_036497413	DNA topoisomerase I [Nocardia aobensis].	26.09	322	188	10	47	356	272	555	7e-12	78.2
rs:WP_020527395	hypothetical protein [Flexithrix dorotheae].	28.88	277	155	11	65	334	238	479	7e-12	78.2
rs:WP_021417477	DNA topoisomerase I, partial [Peptoclostridium difficile].	20.83	408	270	8	36	428	215	584	7e-12	77.8
rs:WP_001947707	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	7e-12	78.2
tr:A0A0F3N6Q0_ANAPH	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJV63710.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KJV63710.1};	26.25	320	180	11	46	347	231	512	7e-12	77.8
rs:WP_043895451	DNA topoisomerase I [Porphyromonas gingivalis].	27.88	269	152	8	77	338	248	481	7e-12	78.2
tr:U2LFN4_PORGN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	27.88	269	152	8	77	338	275	508	7e-12	78.2
rs:WP_000681401	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	7e-12	78.2
rs:WP_038832236	DNA topoisomerase I [Yersinia pestis].	24.47	380	236	13	77	446	290	628	7e-12	78.2
rs:WP_033848486	DNA topoisomerase I [Yersinia wautersii].	24.47	380	236	13	77	446	290	628	7e-12	78.2
rs:WP_008746511	DNA topoisomerase I [Streptomyces sp. SPB74].	24.93	341	201	12	35	354	250	556	7e-12	78.2
rs:WP_029299451	DNA topoisomerase I [Aeromonas hydrophila].	24.05	420	261	14	49	452	259	636	7e-12	78.2
rs:WP_005875040	DNA topoisomerase I [Porphyromonas gingivalis].	27.88	269	152	8	77	338	248	481	7e-12	78.2
rs:WP_033131079	DNA topoisomerase I [Aeromonas sp. AE235].	24.29	420	260	14	49	452	259	636	7e-12	78.2
rs:WP_008826392	DNA topoisomerase I [Haloplasma contractile].	24.55	391	233	14	77	450	258	603	7e-12	78.2
rs:WP_001970510	DNA topoisomerase I [Helicobacter pylori].	25.76	396	228	17	74	450	251	599	7e-12	78.2
rs:WP_000681403	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	7e-12	78.2
rs:WP_008813642	MULTISPECIES: topoisomerase I [Enterobacteriaceae].	23.67	376	244	12	77	446	284	622	7e-12	78.2
rs:WP_036901617	MULTISPECIES: DNA topoisomerase I [Propionibacterium].	25.26	384	221	16	35	388	243	590	7e-12	78.2
rs:WP_012496557	DNA topoisomerase I [Rhodopseudomonas palustris].	24.71	433	248	15	61	454	244	637	7e-12	78.2
rs:WP_011158669	DNA topoisomerase I [Rhodopseudomonas palustris].	24.83	431	250	14	61	454	244	637	7e-12	78.2
rs:XP_002153907	PREDICTED: DNA topoisomerase 3-beta-1-like [Hydra vulgaris].	24.62	333	212	9	40	367	256	554	7e-12	78.2
rs:WP_017985457	DNA topoisomerase I [Amycolatopsis methanolica].	27.10	369	215	13	66	411	295	632	7e-12	78.2
rs:XP_004357934	DNA topoisomerase III [Dictyostelium fasciculatum].	25.85	325	186	12	86	398	324	605	7e-12	78.2
rs:WP_013816449	DNA topoisomerase I [Porphyromonas gingivalis].	27.88	269	152	8	77	338	248	481	7e-12	78.2
rs:WP_012457773	DNA topoisomerase I [Porphyromonas gingivalis].	27.88	269	152	8	77	338	248	481	7e-12	78.2
rs:WP_015829234	DNA topoisomerase I [Methylovorus glucosotrophus].	24.94	453	256	20	22	449	222	615	7e-12	78.2
rs:WP_009883364	DNA topoisomerase I [Brevibacterium linens].	26.19	336	204	11	36	356	250	556	7e-12	78.2
rs:WP_009741725	DNA topoisomerase I [Frankia sp. QA3].	26.26	377	224	13	25	387	356	692	7e-12	78.2
rs:WP_030951013	DNA topoisomerase I [Streptomyces sp. NRRL S-481].	26.28	293	167	11	77	354	299	557	7e-12	78.2
rs:WP_000681481	DNA topoisomerase I [Helicobacter pylori].	25.57	395	230	17	74	450	251	599	7e-12	77.8
rs:WP_000681459	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	7e-12	77.8
rs:WP_035965140	DNA topoisomerase I [Kocuria marina].	25.82	368	213	13	42	379	266	603	7e-12	78.2
rs:WP_008778023	DNA topoisomerase III [Parabacteroides sp. 20_3].	26.14	329	211	9	61	385	262	562	7e-12	77.8
rs:WP_002210622	DNA topoisomerase I [Yersinia pestis].	24.47	380	236	13	77	446	290	628	7e-12	78.2
rs:WP_006629579	DNA topoisomerase I [Halorubrum tebenquichense].	23.82	466	273	17	35	454	242	671	7e-12	78.2
rs:WP_030235859	DNA topoisomerase I [Streptomyces sp. NRRL S-455].	26.28	293	167	11	77	354	299	557	7e-12	78.2
rs:WP_039447261	DNA topoisomerase I [Pedobacter glucosidilyticus].	24.47	282	180	5	70	347	243	495	7e-12	78.2
tr:L7JG16_MAGOP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.65	308	181	9	37	333	255	525	7e-12	77.8
rs:WP_013441072	DNA topoisomerase I [Methylovorus sp. MP688].	24.94	453	256	20	22	449	222	615	7e-12	78.2
rs:WP_045596646	DNA topoisomerase I [Vibrio vulnificus].	25.51	345	214	10	40	377	253	561	7e-12	78.2
rs:WP_041154867	DNA topoisomerase I [Vibrio mytili].	25.13	378	235	13	77	446	291	628	7e-12	78.2
rs:WP_021307189	DNA topoisomerase I [Helicobacter pylori].	24.53	428	259	16	41	450	218	599	7e-12	77.8
rs:XP_002554555	KLTH0F08118p [Lachancea thermotolerans].	26.51	332	199	11	39	357	263	562	7e-12	77.8
rs:WP_036908284	DNA topoisomerase I, partial [Prevotella ruminicola].	26.22	286	164	7	77	345	252	507	7e-12	77.8
rs:WP_043898447	DNA topoisomerase I [Porphyromonas gingivalis].	27.88	269	152	8	77	338	248	481	7e-12	78.2
rs:WP_042329021	DNA topoisomerase I [Dietzia sp. UCD-THP].	25.96	366	206	12	47	387	286	611	7e-12	78.2
rs:WP_033584657	DNA topoisomerase [Streptococcus sp. SR1].	23.73	354	222	12	44	385	245	562	7e-12	77.8
rs:WP_039704144	DNA topoisomerase I [Helicobacter pylori].	24.74	392	236	14	74	450	251	598	7e-12	77.8
rs:WP_002206977	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	7e-12	77.8
gp:CP003231_259	DNA topoisomerase I [Mycoplasma hyorhinis GDL-1]	22.48	387	231	9	83	450	256	592	7e-12	77.8
gp:CP009967_4	DNA topoisomerase family protein [Bacillus cereus E33L]	31.07	177	104	5	284	448	1	171	7e-12	75.1
rs:WP_016607025	topoisomerase I [Yersinia pestis].	24.47	380	236	13	77	446	257	595	7e-12	78.2
rs:WP_031103564	DNA topoisomerase I [Streptomyces sp. NRRL S-146].	26.28	293	167	11	77	354	299	557	7e-12	78.2
rs:WP_016775814	DNA topoisomerase I [Anaerophaga thermohalophila].	26.44	261	159	7	77	335	259	488	7e-12	78.2
rs:WP_000237217	DNA topoisomerase III [Streptococcus oralis].	23.08	377	230	12	19	385	236	562	7e-12	77.8
rs:WP_016596023	topoisomerase I, partial [Yersinia pestis].	24.47	380	236	13	77	446	281	619	7e-12	78.2
rs:WP_032584877	DNA topoisomerase I [Bacteroides fragilis].	25.00	264	158	7	77	334	253	482	7e-12	77.8
rs:WP_042633138	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	7e-12	77.8
rs:WP_033758945	DNA topoisomerase I [Helicobacter pylori].	24.75	396	232	16	74	450	251	599	7e-12	77.8
rs:WP_038928411	DNA topoisomerase I, partial [Yersinia pestis].	24.47	380	236	13	77	446	257	595	7e-12	78.2
rs:WP_016594614	topoisomerase I, partial [Yersinia pestis].	24.47	380	236	13	77	446	259	597	7e-12	78.2
rs:WP_038893575	DNA topoisomerase I [Yersinia pestis].	24.47	380	236	13	77	446	290	628	7e-12	78.2
rs:WP_012127429	topoisomerase I [Vibrio campbellii].	25.13	386	225	13	77	446	291	628	7e-12	78.2
rs:WP_030189603	MULTISPECIES: DNA topoisomerase I [Streptomyces].	26.99	289	170	10	77	354	301	559	7e-12	78.2
rs:WP_030113344	MULTISPECIES: DNA topoisomerase I [Streptomyces].	26.99	289	170	10	77	354	301	559	7e-12	78.2
rs:WP_018551170	DNA topoisomerase I [Streptomyces sp. ATexAB-D23].	26.28	293	167	11	77	354	301	559	7e-12	78.2
rs:WP_030724800	MULTISPECIES: DNA topoisomerase I [Streptomyces].	26.99	289	170	10	77	354	301	559	7e-12	78.2
rs:WP_000681474	DNA topoisomerase I [Helicobacter pylori].	25.31	399	226	17	74	450	251	599	7e-12	77.8
rs:WP_022894038	DNA topoisomerase I [Agromyces subbeticus].	26.28	312	164	10	77	356	290	567	7e-12	78.2
rs:WP_029563674	DNA topoisomerase I [alpha proteobacterium SCGC AAA240-E13].	23.09	433	270	13	51	454	234	632	7e-12	78.2
rs:WP_005846717	MULTISPECIES: DNA topoisomerase III [Bacteroides].	24.80	379	242	11	18	385	216	562	7e-12	77.8
rs:WP_037682683	DNA topoisomerase I [Streptomyces griseus].	26.55	290	170	10	77	354	299	557	7e-12	78.2
rs:WP_030260198	DNA topoisomerase I [Streptomyces violens].	26.62	293	166	11	77	354	301	559	7e-12	78.2
tr:E4Y9R3_OIKDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.07	435	271	15	39	453	256	642	7e-12	78.2
rs:WP_000314621	DNA topoisomerase I subunit omega, partial [Escherichia coli].	26.83	287	176	8	166	446	41	299	7e-12	77.4
rs:WP_025796836	DNA topoisomerase I [Hafnia alvei].	24.30	321	206	8	77	394	284	570	7e-12	78.2
rs:WP_038357410	DNA topoisomerase I, partial [Bacillus anthracis].	26.26	278	175	9	34	296	210	472	7e-12	77.4
rs:WP_038911200	DNA topoisomerase I [Dickeya dadantii].	24.23	421	260	15	40	446	250	625	7e-12	78.2
rs:WP_023427494	DNA topoisomerase I, archaeal [uncultured Acidilobus sp. OSP8].	28.84	319	182	10	45	354	254	536	7e-12	78.2
rs:WP_020272722	DNA topoisomerase 1 [Streptomyces afghaniensis].	26.28	293	167	11	77	354	299	557	7e-12	78.2
rs:WP_030342291	DNA topoisomerase I [Streptomyces floridae].	26.99	289	170	10	77	354	301	559	7e-12	78.2
rs:WP_006880965	topoisomerase I [Vibrio brasiliensis].	25.07	335	198	11	69	386	276	574	7e-12	78.2
rs:WP_020422667	DNA topoisomerase I [Amycolatopsis sp. ATCC 39116].	27.10	369	215	13	66	411	295	632	7e-12	78.2
rs:WP_045620526	DNA topoisomerase I [Vibrio vulnificus].	25.51	345	214	10	40	377	253	561	8e-12	78.2
rs:WP_011413890	DNA topoisomerase I [Erythrobacter litoralis].	23.51	485	306	14	1	452	171	623	8e-12	77.8
rs:WP_020015843	DNA topoisomerase I [Promicromonospora sukumoe].	28.16	348	197	14	35	356	243	563	8e-12	78.2
rs:WP_001974755	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	8e-12	77.8
rs:WP_024524613	DNA topoisomerase I [Edwardsiella hoshinae].	24.51	355	224	10	42	386	249	569	8e-12	78.2
rs:WP_006492023	DNA topoisomerase 1 [Mesotoga infera].	25.36	347	204	11	48	377	222	530	8e-12	77.8
rs:WP_021112282	DNA topoisomerase I [[Haemophilus] parasuis].	26.86	283	170	8	77	356	292	540	8e-12	78.2
rs:WP_039933303	DNA topoisomerase I [Streptomyces viridochromogenes].	26.28	293	167	11	77	354	299	557	8e-12	78.2
rs:WP_022676334	DNA topoisomerase I [Novosphingobium sp. B-7].	26.60	406	239	17	70	452	251	620	8e-12	78.2
rs:WP_021173223	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	8e-12	77.8
rs:WP_015644696	DNA topoisomerase I [Helicobacter pylori].	25.44	401	223	17	74	450	251	599	8e-12	77.8
rs:WP_000681490	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	8e-12	77.8
rs:WP_000681441	DNA topoisomerase I [Helicobacter pylori].	25.82	395	229	17	74	450	251	599	8e-12	77.8
rs:WP_033296544	DNA topoisomerase I [Streptomyces atroolivaceus].	26.64	289	171	10	77	354	299	557	8e-12	78.2
rs:WP_042575756	DNA topoisomerase I [Rhodococcus sp. MEB064].	27.03	333	202	10	35	354	260	564	8e-12	78.2
tr:G9YAG8_HAFAL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.67	376	244	12	77	446	325	663	8e-12	78.2
tr:A2C7C2_PROM3	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.67	381	236	9	40	398	266	617	8e-12	78.2
rs:WP_021663473	DNA topoisomerase I [Porphyromonas gingivalis].	27.88	269	152	8	77	338	248	481	8e-12	77.8
rs:WP_033586562	DNA topoisomerase I [Helicobacter pylori].	25.06	395	232	16	74	450	251	599	8e-12	77.8
rs:WP_016305480	DNA topoisomerase I [Lachnospiraceae bacterium A2].	24.32	440	277	13	36	457	213	614	8e-12	77.8
rs:WP_007832816	DNA topoisomerase III [Bacteroides dorei].	26.14	329	211	9	61	385	262	562	8e-12	77.8
tr:A0A087SYP0_9ARAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.88	371	215	13	102	449	5	338	8e-12	77.4
rs:WP_008209996	DNA topoisomerase I [Rhodanobacter sp. 115].	26.24	343	203	12	60	380	247	561	8e-12	77.8
rs:WP_040161716	DNA topoisomerase I [Helicobacter pylori].	25.76	396	228	18	74	450	251	599	8e-12	77.8
rs:WP_039154270	DNA topoisomerase I [Gallibacterium anatis].	24.80	375	241	12	77	446	290	628	8e-12	77.8
rs:XP_007778801	hypothetical protein W97_02712 [Coniosporium apollinis CBS 100218].	23.32	386	227	10	39	393	258	605	8e-12	77.8
rs:WP_047709099	DNA topoisomerase I [Plesiomonas sp. ZOR0011].	25.69	397	243	18	61	446	273	628	8e-12	77.8
rs:WP_021677229	DNA topoisomerase I [Porphyromonas gingivalis].	27.88	269	152	8	77	338	248	481	8e-12	77.8
rs:WP_045725701	DNA topoisomerase I [Clostridium baratii].	22.77	426	267	13	48	454	225	607	8e-12	77.8
rs:WP_023173440	DNA topoisomerase I [Gloeobacter kilaueensis].	24.42	434	258	18	47	453	228	618	8e-12	77.8
rs:WP_033616372	DNA topoisomerase I [Helicobacter pylori].	25.76	396	228	17	74	450	251	599	8e-12	77.8
rs:WP_010595034	MULTISPECIES: DNA topoisomerase I [Rhodococcus].	25.84	329	198	9	41	354	265	562	8e-12	77.8
rs:WP_025159114	DNA topoisomerase I [Leifsonia aquatica].	26.96	345	201	12	30	354	238	551	8e-12	77.8
rs:WP_009716793	DNA topoisomerase I [Streptomyces himastatinicus].	25.60	293	169	11	77	354	301	559	8e-12	77.8
rs:WP_043247813	DNA topoisomerase I [Streptomyces vinaceus].	27.15	291	167	11	77	354	301	559	8e-12	77.8
rs:WP_003935250	DNA topoisomerase I subunit omega [Rhodococcus ruber].	25.84	329	198	9	41	354	265	562	8e-12	77.8
rs:WP_024637753	DNA topoisomerase I, partial [Mycobacterium avium].	25.77	326	189	10	35	338	257	551	8e-12	77.4
rs:WP_008315788	DNA topoisomerase 1 [Wohlfahrtiimonas chitiniclastica].	26.88	398	213	16	56	416	243	599	8e-12	77.8
tr:H5E0H1_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.83	287	176	8	166	446	60	318	8e-12	77.4
rs:XP_012523359	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Monomorium pharaonis].	24.58	415	249	14	60	449	342	717	8e-12	78.2
rs:WP_008627226	DNA topoisomerase I [Paraprevotella xylaniphila].	26.05	261	162	6	77	335	251	482	8e-12	77.8
tr:A0A087GIK6_ARAAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.85	436	262	13	54	450	689	1093	8e-12	78.2
rs:WP_002766624	DNA topoisomerase I [Leptospira borgpetersenii].	22.17	442	276	15	40	456	82	480	8e-12	77.4
rs:WP_013933412	DNA topoisomerase I [Zymomonas mobilis].	24.83	439	261	16	47	452	228	630	8e-12	77.8
rs:WP_023770068	MULTISPECIES: DNA topoisomerase I [Mesorhizobium].	24.94	449	263	18	41	452	224	635	8e-12	77.8
rs:WP_034004204	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	24.84	318	187	10	166	459	9	298	8e-12	75.9
rs:XP_003868447	Top3 protein [Candida orthopsilosis Co 90-125].	24.19	339	212	8	53	378	270	576	8e-12	77.4
tr:T2N8B6_PORGN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.88	269	152	8	77	338	280	513	8e-12	77.8
rs:WP_038922768	DNA topoisomerase I [Dickeya dadantii].	24.23	421	260	15	40	446	249	624	8e-12	77.8
rs:WP_013317897	topoisomerase I [Dickeya dadantii].	24.23	421	260	15	40	446	249	624	8e-12	77.8
tr:A0A0E9FFT9_CHLTH	SubName: Full=DNA topoisomerase I-fused to SWI domain {ECO:0000313|EMBL:CRH80440.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRH80440.1};	26.00	250	143	8	211	452	8	223	8e-12	75.9
rs:WP_048344841	DNA topoisomerase I [Lactobacillus mucosae].	23.91	435	255	17	43	452	257	640	8e-12	77.8
rs:XP_003713792	DNA topoisomerase III [Magnaporthe oryzae 70-15].	25.65	308	181	9	37	333	255	525	8e-12	77.8
rs:WP_013760650	DNA topoisomerase I [Porphyromonas asaccharolytica].	26.89	264	152	7	77	334	253	481	8e-12	77.8
rs:WP_028776179	DNA topoisomerase I [Shimazuella kribbensis].	21.58	431	280	12	41	452	218	609	8e-12	77.8
tr:F4X1K5_ACREC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.15	445	259	16	40	449	207	603	8e-12	77.8
rs:XP_008206402	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Nasonia vitripennis].	23.71	388	234	14	18	385	182	527	8e-12	77.8
rs:WP_022901482	DNA topoisomerase I [Humibacter albus].	24.64	345	210	11	30	354	238	552	8e-12	77.8
rs:WP_046651444	DNA topoisomerase I [Corynebacterium xerosis].	25.43	291	173	8	77	351	298	560	8e-12	77.8
rs:WP_015810713	DNA topoisomerase I [Dyadobacter fermentans].	28.00	275	164	9	68	340	242	484	9e-12	77.8
rs:WP_000681501	DNA topoisomerase I [Helicobacter pylori].	24.94	393	229	16	77	450	254	599	9e-12	77.8
rs:WP_033763286	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	9e-12	77.8
tr:D9X3Y8_STRVR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.28	293	167	11	77	354	312	570	9e-12	77.8
rs:WP_036914349	DNA topoisomerase I [Prevotella sp. FD3004].	26.30	289	160	8	77	345	252	507	9e-12	77.8
tr:A7HLU3_FERNB	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.38	326	189	10	70	379	276	566	9e-12	77.8
rs:WP_030334395	DNA topoisomerase I [Streptomyces sp. NRRL B-1381].	26.99	289	170	10	77	354	301	559	9e-12	77.8
rs:WP_046754024	DNA topoisomerase I [Mycobacterium elephantis].	25.53	376	218	11	55	399	282	626	9e-12	77.8
rs:WP_017790186	topoisomerase I [Vibrio vulnificus].	25.22	345	215	10	40	377	253	561	9e-12	77.8
rs:WP_044385305	DNA topoisomerase I [Marinobacter excellens].	23.64	423	266	13	36	446	255	632	9e-12	77.8
rs:WP_021306574	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	9e-12	77.8
rs:WP_010275225	topoisomerase I [Pectobacterium carotovorum].	25.06	399	243	13	61	446	268	623	9e-12	77.8
rs:WP_027933602	DNA topoisomerase I [Amycolatopsis thermoflava].	27.10	369	215	13	66	411	295	632	9e-12	77.8
rs:WP_010278379	DNA topoisomerase I [Leuconostoc pseudomesenteroides].	24.82	415	230	19	66	452	238	598	9e-12	77.4
rs:WP_025278686	DNA topoisomerase I [Barnesiella viscericola].	26.60	297	186	6	40	334	212	478	9e-12	77.8
rs:WP_022083390	DNA topoisomerase [Bacteroides sp. CAG:144].	25.75	299	187	7	40	334	123	390	9e-12	77.8
rs:WP_040965890	DNA topoisomerase I [Erythrobacter vulgaris].	26.35	334	201	11	41	372	222	512	9e-12	77.8
rs:WP_012386322	DNA topoisomerase I [Beijerinckia indica].	25.73	443	258	14	45	452	228	634	9e-12	77.8
tr:L0P8R6_PNEJ8	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.50	320	175	13	70	369	298	580	9e-12	77.4
rs:WP_039517280	DNA topoisomerase I [Pectobacterium carotovorum].	25.06	399	243	13	61	446	268	623	9e-12	77.8
rs:WP_015772462	DNA topoisomerase I [Jonesia denitrificans].	27.98	336	177	13	47	356	260	556	9e-12	77.8
rs:WP_046581580	DNA topoisomerase I [Streptomyces sp. MUSC149T].	26.71	292	167	11	77	354	299	557	9e-12	77.8
rs:WP_036496366	DNA topoisomerase I, partial [Nocardia sp. BMG111209].	26.30	327	185	10	45	356	286	571	9e-12	77.8
rs:WP_039164285	DNA topoisomerase I [Gallibacterium anatis].	24.80	375	241	12	77	446	290	628	9e-12	77.8
rs:WP_033979247	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	24.84	318	187	10	166	459	10	299	9e-12	75.5
rs:WP_011057718	DNA topoisomerase I [Thermosynechococcus elongatus].	26.26	358	217	11	41	385	249	572	9e-12	77.8
rs:WP_018547966	DNA topoisomerase I [Streptomyces sp. LaPpAH-108].	25.44	342	199	12	35	354	250	557	9e-12	77.8
rs:WP_022035402	GTP-sensing transcriptional pleiotropic repressor CodY [Roseburia sp. CAG:50].	24.53	424	263	13	48	454	83	466	9e-12	77.4
rs:WP_027036790	DNA topoisomerase I [Mesorhizobium ciceri].	25.33	450	260	19	41	452	224	635	9e-12	77.8
rs:WP_025222407	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	9e-12	77.8
rs:WP_000681472	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	9e-12	77.8
rs:WP_045311571	DNA topoisomerase I [Lechevalieria aerocolonigenes].	25.38	327	202	10	41	354	268	565	9e-12	77.8
rs:WP_038821515	DNA topoisomerase III, partial [Pseudomonas syringae].	37.11	97	58	1	47	143	223	316	9e-12	75.9
rs:WP_012526797	DNA topoisomerase I [Anaeromyxobacter sp. K].	22.94	449	258	15	49	452	273	678	9e-12	77.8
rs:WP_034821487	DNA topoisomerase I [Enterobacter cancerogenus].	26.63	323	187	11	77	386	284	569	9e-12	77.8
tr:A0A0B8PS58_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAM65459.1};	25.75	233	107	5	293	459	1	233	9e-12	74.7
rs:WP_009871082	Topoisomerase IA [Magnetospirillum magnetotacticum].	25.70	428	250	14	60	454	243	635	9e-12	77.8
rs:WP_018405529	topoisomerase I [Marinobacter lipolyticus].	25.63	398	247	15	59	446	276	634	9e-12	77.8
tr:J9FUN1_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EJW98213.1};	25.23	329	186	8	47	350	221	514	9e-12	77.8
rs:WP_025366675	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	9e-12	77.4
tr:I2WF47_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.83	287	176	8	166	446	60	318	9e-12	77.4
rs:WP_018332835	hypothetical protein [Actinomycetospora chiangmaiensis].	25.82	368	221	13	35	379	307	645	9e-12	77.8
tr:K1YG08_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.54	407	232	18	66	452	248	607	9e-12	77.4
rs:WP_035729183	DNA topoisomerase I [Frankia sp. Allo2].	25.07	359	229	10	42	387	357	688	9e-12	77.8
tr:W7C9Q7_9LIST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	23.70	346	213	11	50	377	110	422	9e-12	77.0
rs:WP_038863258	DNA topoisomerase I [Vibrio campbellii].	25.13	386	225	13	77	446	291	628	9e-12	77.8
rs:WP_016669102	DNA topoisomerase I [Propionibacterium sp. oral taxon 192].	25.95	343	187	11	35	350	248	550	9e-12	77.8
rs:WP_000681491	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	9e-12	77.4
rs:XP_001606777	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Nasonia vitripennis].	23.97	388	233	14	18	385	235	580	9e-12	77.8
rs:WP_015658842	DNA topoisomerase 1 [Streptomyces davawensis].	26.28	293	167	11	77	354	299	557	9e-12	77.8
rs:WP_023833737	DNA topoisomerase I [Mesorhizobium sp. L103C105A0].	25.62	445	257	19	45	452	228	635	9e-12	77.8
rs:WP_010986045	DNA topoisomerase I [Streptomyces avermitilis].	24.93	337	207	10	35	354	250	557	9e-12	77.8
rs:WP_039344991	DNA topoisomerase I [Pectobacterium carotovorum].	25.31	399	242	14	61	446	267	622	9e-12	77.8
rs:WP_001919591	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	9e-12	77.4
rs:WP_048256980	DNA topoisomerase I [Pectobacterium carotovorum].	25.06	399	243	13	61	446	268	623	9e-12	77.8
rs:XP_001746649	hypothetical protein [Monosiga brevicollis MX1].	24.61	447	276	17	39	450	241	661	9e-12	77.8
rs:WP_034913033	DNA topoisomerase I [Gilliamella apicola].	25.29	431	255	17	43	452	252	636	9e-12	77.8
rs:WP_041257161	DNA topoisomerase I, partial [Fervidobacterium nodosum].	26.38	326	189	10	70	379	243	533	9e-12	77.4
tr:K2A4J6_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.45	440	258	17	36	452	214	606	9e-12	77.4
rs:WP_000681504	DNA topoisomerase I [Helicobacter pylori].	25.57	395	230	17	74	450	251	599	1e-11	77.4
rs:WP_008449636	DNA topoisomerase I [Prevotella amnii].	25.37	268	158	7	77	334	253	488	1e-11	77.4
rs:WP_011438659	MULTISPECIES: DNA topoisomerase I [Frankia].	25.07	359	229	10	42	387	357	688	1e-11	77.8
rs:WP_005656946	DNA topoisomerase III [Bacteroides stercoris].	24.54	379	243	11	18	385	216	562	1e-11	77.4
rs:WP_015618537	DNA topoisomerase I [Actinoplanes sp. N902-109].	26.96	382	224	17	47	409	266	611	1e-11	77.8
tr:L8XD87_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.87	386	226	13	77	446	214	551	1e-11	77.8
rs:WP_000681447	DNA topoisomerase I [Helicobacter pylori].	24.56	399	229	17	74	450	251	599	1e-11	77.4
gp:CP007365_941	hypothetical protein [Salmonella enterica subsp. enterica serovar Enteritidis str.]	26.83	287	176	8	166	446	45	303	1e-11	76.3
rs:WP_036105439	DNA topoisomerase I [Mangrovibacter sp. MFB070].	25.08	319	195	10	77	385	284	568	1e-11	77.8
rs:WP_007390460	DNA topoisomerase I [Megasphaera sp. UPII 199-6].	25.51	396	230	15	77	452	313	663	1e-11	77.4
rs:WP_015428573	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	1e-11	77.4
rs:WP_029069541	DNA topoisomerase I [Jonesia quinghaiensis].	29.39	296	164	11	77	356	290	556	1e-11	77.8
rs:WP_042506432	DNA topoisomerase I [Algibacter lectus].	26.88	279	165	7	61	334	233	477	1e-11	77.8
rs:WP_027586796	DNA topoisomerase I [Propionibacterium thoenii].	26.07	349	198	12	51	379	280	588	1e-11	77.8
rs:WP_017284169	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	1e-11	77.4
rs:WP_042808036	DNA topoisomerase I [Streptomyces rimosus].	26.64	289	171	10	77	354	301	559	1e-11	77.8
tr:W4I284_MYCGS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.39	379	229	13	41	399	244	592	1e-11	77.8
rs:WP_013615831	DNA topoisomerase I [Deinococcus proteolyticus].	27.82	266	152	7	86	347	295	524	1e-11	77.4
rs:WP_033592450	DNA topoisomerase I [Helicobacter pylori].	24.75	396	232	16	74	450	251	599	1e-11	77.4
rs:WP_003573867	DNA topoisomerase I [Rhizobium leguminosarum].	24.60	439	268	15	47	452	230	638	1e-11	77.8
rs:WP_008582161	DNA topoisomerase I [Halorubrum hochstenium].	23.23	465	276	16	35	454	242	670	1e-11	77.8
rs:WP_017033749	topoisomerase I [Vibrio genomosp. F10].	25.06	391	243	13	68	446	275	627	1e-11	77.8
rs:WP_029838722	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	1e-11	77.8
rs:WP_011261684	DNA topoisomerase I [Aliivibrio fischeri].	25.53	380	231	14	77	446	289	626	1e-11	77.8
rs:WP_026819570	DNA topoisomerase I [Arthrobacter castelli].	24.01	354	226	9	42	380	265	590	1e-11	77.8
rs:WP_015071551	DNA topoisomerase [Propionibacterium acidipropionici].	23.50	366	226	11	36	379	251	584	1e-11	77.8
rs:WP_001981450	DNA topoisomerase I [Helicobacter pylori].	24.62	394	235	14	74	450	251	599	1e-11	77.4
rs:WP_045814401	DNA topoisomerase I [Pantoea sp. SM3].	26.63	323	187	11	77	386	284	569	1e-11	77.4
sp:TOP1_AERPE	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.87	375	216	13	74	421	273	612	1e-11	77.4
tr:H4K211_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.83	287	176	8	166	446	60	318	1e-11	77.0
gp:CP002744_994	DNA topoisomerase I/SWI domain fusion protein [Chlamydia psittaci Mat116]	24.75	396	247	17	69	449	135	494	1e-11	77.4
rs:WP_022989227	topoisomerase I [Marinobacter sp. ES-1].	24.49	396	252	14	59	446	276	632	1e-11	77.4
rs:WP_043520017	DNA topoisomerase, partial [Acidobacteriaceae bacterium TAA166].	22.58	465	272	15	34	446	227	655	1e-11	77.8
rs:WP_028494947	MULTISPECIES: DNA topoisomerase I [Microbacterium].	27.99	343	191	12	51	377	269	571	1e-11	77.4
rs:WP_007066093	DNA topoisomerase I [Fulvimarina pelagi].	24.67	458	257	17	43	452	226	643	1e-11	77.8
rs:WP_027291047	DNA topoisomerase I [Rikenella microfusus].	27.40	281	168	9	60	334	234	484	1e-11	77.4
rs:WP_044374915	DNA topoisomerase I, partial [Escherichia coli].	28.14	231	131	6	166	386	30	235	1e-11	75.1
rs:WP_044726341	DNA topoisomerase I, partial [Escherichia coli].	26.83	287	176	8	166	446	30	288	1e-11	77.0
rs:WP_007680956	DNA topoisomerase I [Novosphingobium sp. AP12].	26.18	424	253	16	52	452	233	619	1e-11	77.4
tr:L1KHS5_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.27	368	219	13	77	422	299	632	1e-11	77.8
rs:XP_002881210	DNA topoisomerase family protein [Arabidopsis lyrata subsp. lyrata].	23.58	318	201	10	40	351	258	539	1e-11	77.4
rs:WP_033613056	DNA topoisomerase I [Helicobacter pylori].	24.75	396	232	16	74	450	251	599	1e-11	77.4
rs:XP_002947763	hypothetical protein VOLCADRAFT_79791 [Volvox carteri f. nagariensis].	24.48	388	238	13	37	407	272	621	1e-11	77.8
rs:WP_048017667	DNA topoisomerase I [Synechococcus sp. GFB01].	27.32	388	233	13	30	398	237	594	1e-11	77.4
rs:WP_033822956	DNA topoisomerase I [Kitasatospora sp. MBT63].	25.51	294	168	12	77	354	299	557	1e-11	77.8
rs:WP_047883328	DNA topoisomerase I [Photobacterium ganghwense].	25.13	382	230	15	77	446	290	627	1e-11	77.4
rs:WP_001956918	DNA topoisomerase I [Helicobacter pylori].	24.62	394	235	14	74	450	251	599	1e-11	77.4
rs:WP_000681486	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	1e-11	77.4
tr:A0A0E4CQT3_9MYCO	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CQD21861.1};	24.68	389	231	12	41	399	270	626	1e-11	77.4
rs:WP_002529102	DNA topoisomerase I [Propionibacterium humerusii].	24.68	385	230	14	34	388	236	590	1e-11	77.4
rs:XP_009252924	hypothetical protein FPSE_01529 [Fusarium pseudograminearum CS3096].	25.53	333	200	10	18	339	232	527	1e-11	77.4
rs:WP_037850552	DNA topoisomerase I [Streptomyces sp. NRRL S-340].	26.62	293	166	11	77	354	299	557	1e-11	77.4
rs:WP_025639521	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	24.94	389	239	14	77	452	291	639	1e-11	77.4
rs:WP_000681508	DNA topoisomerase I [Helicobacter pylori].	24.48	429	258	16	41	450	218	599	1e-11	77.4
rs:WP_030799698	DNA topoisomerase I [Streptomyces sp. NRRL F-3273].	26.99	289	170	10	77	354	301	559	1e-11	77.4
rs:WP_039944916	DNA topoisomerase I [Lactobacillus mucosae].	23.45	435	257	16	43	452	257	640	1e-11	77.4
rs:WP_027773285	DNA topoisomerase I [Streptomyces sp. CNQ329].	26.11	383	233	14	47	411	269	619	1e-11	77.4
rs:WP_033622086	DNA topoisomerase I [Helicobacter pylori].	24.75	396	232	16	74	450	251	599	1e-11	77.4
tr:A0A0C6FPS9_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.55	458	234	19	43	452	236	634	1e-11	77.4
rs:WP_010863937	DNA topoisomerase I subunit omega [Plesiomonas shigelloides].	25.25	396	246	17	61	446	273	628	1e-11	77.4
rs:WP_021958984	DNA topoisomerase [Brachyspira sp. CAG:700].	21.33	422	275	13	47	451	242	623	1e-11	77.4
rs:XP_003655718	hypothetical protein THITE_2119715 [Thielavia terrestris NRRL 8126].	26.40	303	178	9	40	334	258	523	1e-11	77.4
rs:WP_038646692	DNA topoisomerase I [Pantoea rwandensis].	27.55	323	184	12	77	386	284	569	1e-11	77.4
rs:WP_000681478	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	1e-11	77.4
rs:WP_009067753	MULTISPECIES: DNA topoisomerase I [Streptomyces].	24.63	341	202	12	35	354	250	556	1e-11	77.4
rs:WP_007823869	DNA topoisomerase I [Streptomyces sp. Tu6071].	24.63	341	202	12	35	354	250	556	1e-11	77.4
rs:WP_000681448	DNA topoisomerase I [Helicobacter pylori].	25.57	395	230	17	74	450	251	599	1e-11	77.4
rs:WP_037257920	DNA topoisomerase I, partial [Rhodovibrio salinarum].	23.95	430	260	16	61	454	246	644	1e-11	77.4
rs:WP_023720102	DNA topoisomerase I [Mesorhizobium sp. LSHC420B00].	24.94	445	268	16	41	452	224	635	1e-11	77.4
rs:WP_023783252	DNA topoisomerase I [Mesorhizobium sp. LNHC220B00].	24.94	449	263	18	41	452	224	635	1e-11	77.4
rs:WP_028245271	DNA topoisomerase I [Pseudoclavibacter soli].	24.19	339	214	9	31	354	240	550	1e-11	77.4
rs:WP_010358422	DNA topoisomerase I [Streptomyces acidiscabies].	26.62	293	166	11	77	354	299	557	1e-11	77.4
rs:WP_000681524	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	1e-11	77.4
rs:WP_000681466	DNA topoisomerase I [Helicobacter pylori].	24.94	393	235	14	74	450	251	599	1e-11	77.4
tr:A0A0F0CL87_9BACT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJJ84103.1};	24.48	478	269	20	36	457	251	692	1e-11	77.4
tr:G8BAX5_CANPC	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:CCE42199.1};	22.25	355	231	8	53	394	270	592	1e-11	77.0
rs:XP_011398429	DNA topoisomerase 3-alpha [Auxenochlorella protothecoides].	27.81	356	216	10	31	378	201	523	1e-11	77.4
rs:WP_042831491	DNA topoisomerase I [Streptomyces rimosus].	26.64	289	171	10	77	354	301	559	1e-11	77.4
rs:WP_036464620	DNA topoisomerase I [Mycoplasma sturni].	24.80	383	206	14	92	449	272	597	1e-11	77.0
rs:WP_030597724	DNA topoisomerase I [Streptomyces rimosus].	26.64	289	171	10	77	354	301	559	1e-11	77.4
rs:WP_031676086	DNA topoisomerase I [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	271	622	1e-11	77.4
rs:WP_001946536	DNA topoisomerase I [Helicobacter pylori].	24.62	394	235	14	74	450	251	599	1e-11	77.4
rs:WP_024773959	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	1e-11	77.4
rs:WP_015547003	DNA topoisomerase I [Alistipes shahii].	24.09	303	196	6	40	339	214	485	1e-11	77.4
rs:XP_001483632	hypothetical protein PGUG_04361 [Meyerozyma guilliermondii ATCC 6260].	26.20	355	211	10	49	385	268	589	1e-11	77.0
rs:WP_000681438	DNA topoisomerase I [Helicobacter pylori].	24.75	396	232	16	74	450	251	599	1e-11	77.4
rs:WP_000681429	DNA topoisomerase I [Helicobacter pylori].	24.75	396	232	16	74	450	251	599	1e-11	77.4
rs:WP_036105783	DNA topoisomerase I [Lysobacter capsici].	28.93	318	178	13	50	350	238	524	1e-11	77.4
rs:WP_033396689	hypothetical protein, partial [Thermodesulfobacterium thermophilum].	26.33	338	197	12	67	393	246	542	1e-11	77.0
rs:WP_004571867	MULTISPECIES: DNA topoisomerase I [Streptomyces].	26.64	289	171	10	77	354	301	559	1e-11	77.4
rs:WP_030374829	MULTISPECIES: DNA topoisomerase I [Streptomyces].	26.64	289	171	10	77	354	301	559	1e-11	77.4
rs:WP_024116767	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	1e-11	77.4
rs:WP_001972196	DNA topoisomerase I [Helicobacter pylori].	25.51	396	229	17	74	450	251	599	1e-11	77.4
rs:WP_001952760	DNA topoisomerase I [Helicobacter pylori].	24.62	394	235	14	74	450	251	599	1e-11	77.4
rs:WP_021301973	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	1e-11	77.4
tr:V5GCH8_BYSSN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.79	359	190	10	73	395	294	608	1e-11	77.0
rs:WP_022408208	DNA topoisomerase [Clostridium sp. CAG:354].	25.15	326	191	8	47	356	226	514	1e-11	77.0
tr:A0A0D3B4H6_BRAOL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.58	318	201	10	40	351	258	539	1e-11	77.4
rs:WP_029827738	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	24.94	389	239	14	77	452	291	639	1e-11	77.0
tr:A0A0D9MAX8_9EURO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.68	342	194	8	41	359	261	558	1e-11	77.0
rs:WP_018048827	hypothetical protein [Nitrospina sp. AB-629-B18].	23.94	426	266	13	47	452	252	639	1e-11	77.4
rs:WP_025791947	DNA topoisomerase I [Vibrio parahaemolyticus].	24.60	378	237	13	77	446	291	628	1e-11	77.4
tr:A0A078DBQ5_BRANA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.58	318	201	10	40	351	255	536	1e-11	77.4
rs:WP_030651823	DNA topoisomerase I [Streptomyces rimosus].	26.64	289	171	10	77	354	301	559	1e-11	77.4
rs:WP_033754862	DNA topoisomerase I [Helicobacter pylori].	24.75	396	232	16	74	450	251	599	1e-11	77.4
rs:WP_027443042	DNA topoisomerase I [Porphyrobacter cryptus].	26.07	491	285	18	1	452	171	622	1e-11	77.4
rs:WP_033009070	hypothetical protein, partial [Xanthomonas vasicola].	25.36	280	175	6	187	459	1	253	1e-11	76.6
tr:K2MRY5_TRYCR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.45	344	198	11	47	380	269	567	1e-11	77.4
rs:WP_038919025	DNA topoisomerase I [Dickeya sp. MK7].	24.94	421	257	16	40	446	249	624	1e-11	77.4
tr:F3P1P8_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.68	385	230	14	34	388	219	573	1e-11	77.4
rs:WP_022051800	DNA topoisomerase [Firmicutes bacterium CAG:631].	22.78	417	234	13	66	450	4	364	1e-11	76.6
rs:WP_000681503	DNA topoisomerase I [Helicobacter pylori].	24.94	393	229	16	77	450	254	599	1e-11	77.4
rs:WP_000681525	DNA topoisomerase I [Helicobacter pylori].	23.93	397	234	15	74	450	251	599	1e-11	77.4
rs:WP_000681428	DNA topoisomerase I [Helicobacter pylori].	25.57	395	230	17	74	450	251	599	1e-11	77.4
rs:WP_021582057	DNA topoisomerase I [Helicobacter pylori].	24.75	396	232	16	74	450	251	599	1e-11	77.4
rs:WP_046658174	DNA topoisomerase I [Lysobacter capsici].	28.93	318	178	13	50	350	238	524	1e-11	77.4
rs:WP_031164975	DNA topoisomerase I [Streptomyces durhamensis].	26.62	293	166	11	77	354	299	557	1e-11	77.4
rs:WP_025550636	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	1e-11	77.4
rs:WP_006530388	DNA topoisomerase I [Gloeocapsa sp. PCC 73106].	23.95	334	222	7	41	370	250	555	1e-11	77.4
tr:X2HCF0_9GAMM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AHN27266.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AHN27266.1};	34.95	103	62	1	232	334	5	102	1e-11	72.4
rs:WP_031819753	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	179	516	1e-11	77.4
rs:XP_007727250	DNA topoisomerase III [Capronia coronata CBS 617.96].	23.84	344	209	10	73	395	294	605	1e-11	77.0
rs:WP_001935335	DNA topoisomerase I [Helicobacter pylori].	24.62	394	235	14	74	450	251	599	1e-11	77.4
rs:WP_035908650	DNA topoisomerase I [Frankia sp. CeD].	25.07	359	229	10	42	387	357	688	1e-11	77.4
rs:WP_031040478	MULTISPECIES: DNA topoisomerase I [Streptomyces].	26.71	292	167	11	77	354	299	557	1e-11	77.4
tr:D2JTF8_STAAU	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ADA54521.1}; Flags: Fragment;	30.92	152	92	3	206	355	1	141	1e-11	72.8
tr:G7E0M5_MIXOS	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:GAA96385.1};	26.32	342	204	10	22	352	237	541	1e-11	77.4
rs:WP_009481330	DNA topoisomerase I [Mobilicoccus pelagius].	27.06	377	215	14	31	379	240	584	1e-11	77.4
rs:WP_033244489	MULTISPECIES: DNA topoisomerase I, partial [Actinobacteria].	25.66	339	204	10	32	354	260	566	1e-11	77.4
tr:K2G267_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.57	259	145	10	102	356	5	227	1e-11	77.0
rs:WP_022251253	DNA topoisomerase [Prevotella sp. CAG:386].	23.23	297	182	7	47	334	233	492	1e-11	77.4
rs:WP_008142805	DNA topoisomerase I [Bacteroides coprophilus].	26.04	265	154	8	77	334	249	478	1e-11	77.4
rs:WP_004810389	DNA topoisomerase I [Propionibacterium avidum].	25.79	380	224	16	35	388	243	590	1e-11	77.4
rs:WP_008106525	topoisomerase I [Pantoea sp. YR343].	26.14	394	229	15	77	452	284	633	1e-11	77.4
rs:WP_020409425	topoisomerase I [Hahella ganghwensis].	24.14	406	257	13	50	446	267	630	1e-11	77.4
rs:WP_004627000	DNA topoisomerase I [[Clostridium] termitidis].	25.63	398	238	12	77	452	256	617	1e-11	77.0
rs:WP_000681419	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	1e-11	77.4
rs:WP_044203746	DNA topoisomerase I [Chlamydia psittaci].	24.75	396	247	17	69	449	238	597	1e-11	77.4
rs:WP_017488557	DNA topoisomerase I [Micrococcus luteus].	27.16	324	199	10	42	354	276	573	1e-11	77.4
rs:WP_022278168	DNA topoisomerase [Bacteroides coprophilus CAG:333].	26.04	265	154	8	77	334	249	478	1e-11	77.4
rs:WP_016215054	DNA topoisomerase I [Eubacterium sp. 14-2].	23.47	426	272	13	48	457	227	614	1e-11	77.0
rs:WP_039088321	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	1e-11	77.0
rs:WP_014857204	DNA topoisomerase I [Melioribacter roseus].	25.17	429	253	17	46	451	250	633	1e-11	77.0
rs:WP_014271302	DNA topoisomerase I [Sphaerochaeta pleomorpha].	24.68	393	249	12	41	415	240	603	1e-11	77.4
rs:WP_013747230	topoisomerase I [Gallibacterium anatis].	24.80	375	241	12	77	446	290	628	1e-11	77.4
rs:WP_036825562	DNA topoisomerase I, partial [Photobacterium sanctipauli].	26.74	374	228	14	80	446	1	335	1e-11	77.0
rs:WP_030734103	DNA topoisomerase I [Streptomyces sp. NRRL S-31].	26.96	293	165	11	77	354	299	557	1e-11	77.4
rs:WP_030043294	DNA topoisomerase I, partial [Streptomyces resistomycificus].	26.39	288	173	9	77	354	140	398	1e-11	77.4
tr:E2Q9N0_STRC2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.21	290	171	10	77	354	316	574	1e-11	77.4
rs:WP_001941587	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	1e-11	77.0
rs:WP_000681527	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	1e-11	77.0
rs:WP_000681482	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	1e-11	77.0
rs:WP_039693966	DNA topoisomerase I [Dickeya solani].	24.23	421	260	15	40	446	249	624	1e-11	77.4
rs:WP_023840729	topoisomerase IA [Frankia sp. CcI6].	25.07	359	229	10	42	387	357	688	1e-11	77.4
rs:WP_036865838	DNA topoisomerase I [Prevotella bivia].	24.22	351	188	10	77	382	253	570	1e-11	77.4
rs:WP_048099629	DNA topoisomerase I [Candidatus Acidianus copahuensis].	24.04	391	241	12	47	424	249	596	1e-11	77.0
rs:WP_009996581	DNA topoisomerase I [Streptomyces clavuligerus].	26.21	290	171	10	77	354	302	560	1e-11	77.4
rs:WP_047804680	DNA topoisomerase I [Kocuria sp. SM24M-10].	26.49	336	192	14	77	389	300	603	1e-11	77.4
rs:WP_046840888	DNA topoisomerase I, partial [Candidatus Synechococcus spongiarum].	27.01	348	213	12	40	377	249	565	1e-11	77.4
rs:WP_006743812	DNA topoisomerase I [Bacteroides coprosuis].	26.94	297	186	8	40	334	216	483	1e-11	77.4
rs:WP_041375056	DNA topoisomerase I [Prochlorococcus marinus].	24.67	381	236	9	40	398	249	600	1e-11	77.4
rs:WP_030998194	DNA topoisomerase I [Streptomyces sp. NRRL F-5630].	26.28	293	167	11	77	354	298	556	1e-11	77.4
rs:WP_000681479	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	1e-11	77.0
rs:XP_011696308	PREDICTED: DNA topoisomerase 3-alpha-like isoform X2 [Wasmannia auropunctata].	24.40	414	249	14	60	449	228	601	1e-11	77.4
tr:B5GPN9_STRC2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.21	290	171	10	77	354	288	546	1e-11	77.4
rs:WP_012633970	DNA topoisomerase I [Anaeromyxobacter dehalogenans].	22.94	449	258	15	49	452	273	678	1e-11	77.4
rs:WP_000681502	DNA topoisomerase I [Helicobacter pylori].	24.81	391	232	14	77	450	254	599	1e-11	77.0
rs:WP_045324926	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	299	636	1e-11	77.4
rs:WP_015707647	DNA topoisomerase I [Treponema primitia].	23.46	422	263	14	49	452	253	632	1e-11	77.0
rs:WP_025627646	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	250	587	1e-11	77.4
rs:WP_030942456	DNA topoisomerase I [Streptomyces sp. NRRL S-646].	26.28	293	167	11	77	354	299	557	1e-11	77.4
rs:WP_009207200	DNA topoisomerase I [Sulfuricella denitrificans].	24.16	418	255	13	56	452	243	619	1e-11	77.0
rs:WP_027019239	DNA topoisomerase I [Corynebacterium sputi].	28.28	290	167	12	77	354	298	558	1e-11	77.4
rs:WP_038953673	DNA topoisomerase I [Bradyrhizobium japonicum].	23.40	423	261	13	61	452	244	634	1e-11	77.4
rs:WP_035276208	DNA topoisomerase I, partial [Actinoalloteichus cyanogriseus].	25.38	394	233	14	38	409	245	599	1e-11	77.0
rs:WP_000681425	DNA topoisomerase I [Helicobacter pylori].	25.51	396	229	17	74	450	251	599	1e-11	77.0
tr:A0A0D1YDN6_9EURO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.16	380	240	12	18	377	234	581	1e-11	77.0
gp:CP007353_1076	DNA topoisomerase I [Salmonella enterica subsp. enterica serovar Enteritidis str.]	26.83	287	176	8	166	446	10	268	1e-11	76.6
tr:A0A0D0DZ36_9HOMO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.11	365	222	11	39	387	258	583	1e-11	77.0
tr:M4LKY8_SALET	SubName: Full=Salmonella enterica subsp. enterica serovar Javiana str. CFSAN001992, complete genome {ECO:0000313|EMBL:AGF80906.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AGF80906.1};	26.83	287	176	8	166	446	35	293	1e-11	76.6
rs:WP_019948085	hypothetical protein [Hymenobacter aerophilus].	27.25	334	208	9	40	367	212	516	1e-11	77.0
rs:WP_000681432	DNA topoisomerase I [Helicobacter pylori].	25.57	395	230	17	74	450	251	599	1e-11	77.0
tr:A0A0E2KMW4_VIBPH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.87	378	236	13	77	446	284	621	1e-11	77.4
tr:W2TUU8_NECAM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.28	360	212	13	39	383	300	617	1e-11	77.4
rs:WP_036411215	DNA topoisomerase I [Mycobacterium gastri].	26.39	379	229	13	41	399	281	629	1e-11	77.4
rs:WP_033601513	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	17	74	450	251	599	1e-11	77.0
rs:WP_021980332	DNA topoisomerase [Paraprevotella clara CAG:116].	25.77	260	162	6	77	334	251	481	1e-11	77.0
tr:G4TIC8_PIRID	SubName: Full=Related to DNA topoisomerase III alpha {ECO:0000313|EMBL:CCA71076.1};	25.66	343	200	12	29	357	219	520	1e-11	77.0
rs:XP_002548196	conserved hypothetical protein [Candida tropicalis MYA-3404].	24.85	342	200	11	56	378	275	578	1e-11	77.0
rs:WP_030615889	DNA topoisomerase I [Streptomyces sclerotialus].	26.28	293	167	11	77	354	301	559	1e-11	77.4
rs:WP_025569872	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	1e-11	77.4
rs:WP_022790860	DNA topoisomerase I [Weissella halotolerans].	22.64	455	247	15	66	455	268	682	1e-11	77.0
rs:WP_033793824	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	17	74	450	251	599	1e-11	77.0
rs:XP_011063790	PREDICTED: DNA topoisomerase 3-alpha-like [Acromyrmex echinatior].	23.15	445	259	16	40	449	303	699	1e-11	77.4
rs:WP_029116849	DNA topoisomerase I [Mycobacterium sp. URHB0044].	27.30	293	167	10	77	354	314	575	1e-11	77.4
rs:WP_012580135	DNA topoisomerase I [Thermosipho africanus].	25.00	352	208	10	60	392	231	545	1e-11	77.0
tr:D4M4K1_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.71	425	268	11	48	457	227	614	1e-11	77.0
rs:WP_009137874	DNA topoisomerase I [Odoribacter laneus].	26.54	260	158	5	77	334	250	478	1e-11	77.0
rs:WP_004395085	topoisomerase I [Vibrio metschnikovii].	25.44	338	195	11	68	386	277	576	1e-11	77.0
rs:WP_000681511	DNA topoisomerase I [Helicobacter pylori].	25.51	396	229	17	74	450	251	599	1e-11	77.0
rs:XP_007557842	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Poecilia formosa].	21.70	447	258	14	40	453	263	650	1e-11	77.0
rs:WP_047689182	DNA topoisomerase I [Kocuria sp. ZOR0020].	26.65	364	224	11	31	377	248	585	1e-11	77.4
rs:WP_018343699	DNA topoisomerase I [Cytophaga aurantiaca].	25.15	342	221	8	1	334	170	484	1e-11	77.0
rs:WP_013272516	DNA topoisomerase I [[Clostridium] saccharolyticum].	23.83	428	267	13	48	457	230	616	1e-11	77.0
tr:A0A090WSL8_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.79	280	165	7	61	334	158	403	1e-11	77.0
rs:WP_044857889	DNA topoisomerase I, partial [Enterobacter cloacae].	27.27	275	161	10	77	347	284	523	1e-11	76.6
rs:WP_031416423	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	1e-11	77.0
rs:XP_011332583	PREDICTED: DNA topoisomerase 3-beta-1 [Cerapachys biroi].	24.04	391	239	14	12	385	231	580	1e-11	77.0
rs:WP_033568758	DNA topoisomerase I [Dickeya sp. 2B12].	24.94	421	257	16	40	446	249	624	1e-11	77.0
rs:WP_043590880	DNA topoisomerase I [Frankia sp. BMG5.23].	25.07	359	229	10	42	387	357	688	1e-11	77.4
rs:WP_029855921	DNA topoisomerase I [Vibrio parahaemolyticus].	24.60	378	237	13	77	446	291	628	1e-11	77.0
rs:WP_025508709	DNA topoisomerase I [Vibrio parahaemolyticus].	24.60	378	237	13	77	446	291	628	1e-11	77.0
rs:XP_010546322	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Tarenaya hassleriana].	26.18	382	220	16	18	377	243	584	1e-11	77.0
rs:WP_030149446	DNA topoisomerase I [Mycetocola saprophilus].	27.55	294	168	9	77	356	288	550	1e-11	77.4
rs:XP_011696307	PREDICTED: DNA topoisomerase 3-alpha-like isoform X1 [Wasmannia auropunctata].	24.40	414	249	14	60	449	319	692	1e-11	77.4
tr:K8DAB0_9ENTR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CCK14063.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CCK14063.1};	41.94	93	54	0	293	385	1	93	1e-11	72.8
rs:WP_041375469	DNA topoisomerase I [Polymorphum gilvum].	24.76	424	246	16	68	452	252	641	1e-11	77.0
rs:WP_031854645	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	198	535	1e-11	77.0
rs:WP_029837348	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	1e-11	77.0
rs:WP_007367631	DNA topoisomerase I [Prevotella multiformis].	25.34	292	166	9	77	350	252	509	1e-11	77.0
rs:WP_022707724	DNA topoisomerase I [Paracoccus zeaxanthinifaciens].	24.90	478	257	18	41	454	223	662	1e-11	77.0
rs:WP_000681488	DNA topoisomerase I [Helicobacter pylori].	25.51	396	229	17	74	450	251	599	1e-11	77.0
rs:WP_026889209	DNA topoisomerase I [Clostridium beijerinckii].	23.23	409	252	12	66	454	242	608	1e-11	77.0
rs:WP_042803046	DNA topoisomerase I [Mannheimia haemolytica].	26.39	379	230	17	77	446	290	628	1e-11	77.0
rs:WP_035525139	DNA topoisomerase I [[Haemophilus] parasuis].	26.50	283	171	8	77	356	292	540	1e-11	77.0
rs:WP_029864275	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	1e-11	77.0
rs:WP_039427755	DNA topoisomerase I [Porphyromonas sp. COT-052 OH4946].	27.82	266	155	8	77	338	248	480	1e-11	77.0
rs:WP_029859090	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	1e-11	77.0
rs:WP_025545701	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	1e-11	77.0
rs:WP_035358326	DNA topoisomerase I [Acholeplasma equifetale].	23.89	427	254	17	47	454	218	592	1e-11	76.6
rs:WP_029362891	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	1e-11	77.0
tr:H1C2Q4_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.88	232	128	8	166	386	60	265	1e-11	75.5
rs:WP_006344557	DNA topoisomerase I [Chlamydophila abortus].	24.29	420	267	17	45	449	239	622	1e-11	77.0
rs:WP_025613452	DNA topoisomerase I [Vibrio parahaemolyticus].	24.60	378	237	13	77	446	291	628	1e-11	77.0
rs:WP_012533245	topoisomerase I [Aliivibrio fischeri].	25.72	381	229	14	77	446	289	626	1e-11	77.0
rs:WP_036514469	DNA topoisomerase I [Nitrincola sp. AK23].	24.62	463	291	17	1	446	210	631	1e-11	77.0
rs:WP_038417165	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	1e-11	77.0
rs:WP_033789637	DNA topoisomerase I [Helicobacter pylori].	24.24	396	234	16	74	450	251	599	1e-11	77.0
rs:WP_044021390	DNA topoisomerase [Streptococcus sp. VT 162].	23.45	354	223	12	44	385	245	562	1e-11	76.6
rs:WP_026739446	DNA topoisomerase I [Lonsdalea quercina].	25.53	380	232	13	77	446	284	622	1e-11	77.0
rs:WP_022389687	DNA topoisomerase [Tannerella sp. CAG:51].	25.67	261	160	6	77	334	253	482	1e-11	77.0
rs:WP_001934270	DNA topoisomerase I [Helicobacter pylori].	24.62	394	235	14	74	450	251	599	1e-11	77.0
rs:WP_042020602	DNA topoisomerase I [Aeromonas sobria].	25.07	347	214	10	49	384	259	570	1e-11	77.0
rs:WP_011445453	DNA topoisomerase I [Novosphingobium aromaticivorans].	25.79	411	236	16	70	452	251	620	1e-11	77.0
rs:WP_031813486	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	1e-11	77.0
tr:F2IVZ0_POLGS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.76	424	246	16	68	452	247	636	1e-11	77.0
rs:WP_022600088	DNA topoisomerase I [Coprobacter fastidiosus].	25.67	261	160	6	77	334	253	482	1e-11	77.0
rs:WP_039090455	DNA topoisomerase I [Helicobacter pylori].	25.51	396	229	17	74	450	251	599	1e-11	77.0
rs:WP_035520262	DNA topoisomerase I [Haemophilus parasuis].	26.50	283	171	8	77	356	292	540	1e-11	77.0
rs:WP_039332040	DNA topoisomerase I [Novosphingobium subterraneum].	25.76	458	268	19	31	452	199	620	1e-11	77.0
rs:WP_023251190	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	26.83	287	176	8	166	446	47	305	1e-11	76.6
rs:WP_033768970	DNA topoisomerase I [Helicobacter pylori].	25.57	395	230	17	74	450	251	599	1e-11	77.0
tr:A0A098DSE7_GIBZA	SubName: Full=Fusarium graminearum chromosome 4, complete genome {ECO:0000313|EMBL:CEF84269.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblFungi:CEF84269};	25.23	333	201	10	18	339	264	559	1e-11	77.0
rs:WP_015296478	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	2e-11	77.0
rs:WP_039617287	DNA topoisomerase I [Campylobacter lari].	24.94	393	229	16	77	450	255	600	2e-11	77.0
rs:WP_045832147	DNA topoisomerase I [Pantoea sp. BL1].	27.55	323	184	12	77	386	284	569	2e-11	77.0
rs:WP_045004125	DNA topoisomerase I [Helicobacter pylori].	25.51	396	229	17	74	450	251	599	2e-11	77.0
rs:WP_000681463	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	2e-11	77.0
rs:WP_037717689	DNA topoisomerase I [Streptomyces mirabilis].	26.28	293	167	11	77	354	299	557	2e-11	77.0
rs:WP_025573646	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	2e-11	77.0
rs:WP_025554134	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	2e-11	77.0
rs:WP_019152081	DNA topoisomerase I [Alistipes senegalensis].	24.42	303	195	6	40	339	214	485	2e-11	77.0
rs:XP_008807900	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Phoenix dactylifera].	25.00	420	237	15	39	451	270	618	2e-11	77.0
tr:A0A0C2GS13_9BILA	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:KIH59771.1};	24.92	317	200	9	40	352	306	588	2e-11	76.6
rs:WP_013998399	DNA topoisomerase I [Capnocytophaga canimorsus].	25.86	290	178	8	56	340	228	485	2e-11	77.0
rs:WP_002360282	DNA topoisomerase, partial [Enterococcus faecium].	29.89	184	123	3	57	237	268	448	2e-11	76.3
gp:CP001641_3380	DNA topoisomerase I [Mycobacterium tuberculosis CCDC5079]	25.33	383	231	11	41	399	271	622	2e-11	77.0
rs:WP_004737437	topoisomerase I [Vibrio splendidus].	24.93	381	232	13	77	446	290	627	2e-11	77.0
rs:WP_031846489	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	2e-11	77.0
rs:WP_025503111	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	2e-11	77.0
rs:WP_021453706	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	2e-11	77.0
rs:WP_008080426	topoisomerase I [Vibrio sinaloensis].	25.51	341	200	12	62	385	270	573	2e-11	77.0
gp:CP007777_164	DNA topoisomerase I [Campylobacter lari RM16701]	24.94	393	229	16	77	450	254	599	2e-11	77.0
rs:WP_038438781	DNA topoisomerase I [Mycobacterium bovis].	25.33	383	231	11	41	399	271	622	2e-11	77.0
rs:WP_015964649	DNA topoisomerase I [Enterobacteriaceae bacterium strain FGI 57].	25.44	283	170	8	77	354	284	530	2e-11	77.0
tr:A0A061ITR9_TRYRA	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESL05201.1};	22.40	433	274	14	39	453	252	640	2e-11	77.0
rs:WP_000681477	DNA topoisomerase I [Helicobacter pylori].	24.53	428	259	16	41	450	218	599	2e-11	77.0
rs:WP_036879037	DNA topoisomerase I [Prevotella oryzae].	25.38	260	163	7	77	334	252	482	2e-11	77.0
rs:WP_018172633	DNA topoisomerase I [Microbacterium sp. 292MF].	28.12	313	180	10	51	354	273	549	2e-11	77.0
rs:WP_019463844	DNA topoisomerase I [Dyella japonica].	28.61	346	190	17	45	371	233	540	2e-11	77.0
rs:XP_008415641	PREDICTED: DNA topoisomerase 3-beta-1 [Poecilia reticulata].	22.90	441	260	16	40	453	263	650	2e-11	77.0
rs:WP_029559254	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	2e-11	77.0
rs:WP_025534169	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	2e-11	77.0
tr:A0A034TW46_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.33	379	234	14	77	446	291	629	2e-11	77.0
rs:WP_030898447	DNA topoisomerase I [Streptomyces sp. NRRL F-5126].	24.84	310	188	9	58	354	280	557	2e-11	77.0
rs:WP_047060003	DNA topoisomerase I [Edwardsiella tarda].	25.94	320	193	10	77	386	284	569	2e-11	77.0
rs:WP_013218143	DNA topoisomerase I [Dehalogenimonas lykanthroporepellens].	20.68	474	271	11	43	450	226	660	2e-11	77.0
rs:WP_029206988	hypothetical protein, partial [alpha proteobacterium SCGC AAA288-G21].	23.62	309	191	8	166	454	66	349	2e-11	76.3
tr:A0A016PR83_GIBZA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EYB28185.1};	25.23	333	201	10	18	339	232	527	2e-11	76.6
rs:WP_041986539	DNA topoisomerase I [Streptomyces sp. AcH 505].	25.94	293	168	11	77	354	299	557	2e-11	77.0
rs:WP_029800337	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	2e-11	77.0
rs:WP_025499340	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	2e-11	77.0
tr:A0A0E8VY41_MYCTX	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CRG31426.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRG31426.1};	25.33	383	231	11	41	399	332	683	2e-11	77.0
rs:WP_012946826	DNA topoisomerase I [Geodermatophilus obscurus].	25.00	328	204	10	42	354	291	591	2e-11	77.0
tr:U1PCP6_9EURY	SubName: Full=Topoisomerase IA {ECO:0000313|EMBL:ERG89851.1}; Flags: Fragment;	25.40	311	183	10	156	454	33	306	2e-11	76.3
rs:WP_001993203	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	232	580	2e-11	77.0
rs:WP_044128842	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	2e-11	77.0
rs:WP_040703664	DNA topoisomerase I [Nocardia takedensis].	25.51	341	200	11	37	354	259	568	2e-11	77.0
rs:WP_005285326	topoisomerase I [Edwardsiella tarda].	25.94	320	193	10	77	386	284	569	2e-11	77.0
rs:WP_033774513	DNA topoisomerase I [Helicobacter pylori].	24.75	396	232	16	74	450	251	599	2e-11	77.0
rs:WP_027074603	DNA topoisomerase I [Mannheimia granulomatis].	25.66	378	234	15	77	446	290	628	2e-11	77.0
tr:G0PNJ8_CAEBE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.78	471	289	19	12	457	33	458	2e-11	76.6
rs:WP_047492508	DNA topoisomerase I [Chryseobacterium sp. OV705].	27.41	321	182	11	24	334	197	476	2e-11	77.0
gp:CP007773_153	DNA topoisomerase I [Campylobacter subantarcticus LMG 24377]	24.68	393	230	16	77	450	254	599	2e-11	76.6
rs:WP_024699954	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	2e-11	77.0
tr:A0A0E7YYV2_MYCTX	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CRD11284.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRD11284.1};	25.33	383	231	11	41	399	332	683	2e-11	77.0
rs:WP_001950705	DNA topoisomerase I [Helicobacter pylori].	25.57	395	230	17	74	450	251	599	2e-11	77.0
rs:WP_042859807	DNA topoisomerase I [Dickeya sp. NCPPB 3274].	24.23	421	260	15	40	446	249	624	2e-11	77.0
rs:WP_025818118	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	2e-11	77.0
rs:WP_025587383	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	2e-11	77.0
rs:WP_005457230	MULTISPECIES: DNA topoisomerase I [Vibrio].	24.87	378	236	13	77	446	291	628	2e-11	77.0
rs:WP_031851619	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	2e-11	77.0
rs:WP_025520612	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	2e-11	77.0
rs:WP_033524661	DNA topoisomerase I [Streptomyces galbus].	26.39	288	173	9	77	354	299	557	2e-11	77.0
rs:WP_016536693	DNA topoisomerase I [Cedecea davisae].	24.73	376	240	12	77	446	284	622	2e-11	77.0
rs:WP_005531228	DNA topoisomerase I [Corynebacterium striatum].	24.73	368	218	14	41	384	255	587	2e-11	77.0
rs:WP_021113464	DNA topoisomerase I [Haemophilus parasuis].	26.50	283	171	8	77	356	292	540	2e-11	77.0
rs:WP_014273075	DNA topoisomerase I [Mycoplasma haemocanis].	24.69	401	245	12	74	457	269	629	2e-11	77.0
rs:WP_027585179	DNA topoisomerase I [Prolixibacter bellariivorans].	26.79	336	181	12	14	335	199	483	2e-11	77.0
rs:WP_025629059	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	2e-11	77.0
rs:WP_009628373	DNA topoisomerase I [Pseudanabaena biceps].	22.92	432	266	14	40	446	240	629	2e-11	77.0
rs:WP_047417259	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	2e-11	76.6
rs:WP_041939924	DNA topoisomerase I [Frankia alni].	26.07	326	197	11	77	387	391	687	2e-11	77.0
rs:WP_002759875	DNA topoisomerase I [Leptospira borgpetersenii].	22.17	442	276	15	40	456	211	609	2e-11	76.6
rs:WP_023679974	DNA topoisomerase I [Mesorhizobium sp. LSJC280B00].	25.51	439	261	16	47	452	230	635	2e-11	77.0
rs:WP_005802573	DNA topoisomerase III [Bacteroides fragilis].	26.44	329	210	9	61	385	262	562	2e-11	76.6
rs:NP_001254381	Y48C3A.14, isoform a [Caenorhabditis elegans].	24.21	475	284	19	12	457	232	659	2e-11	77.0
rs:WP_018102164	MULTISPECIES: DNA topoisomerase I [Streptomyces].	25.86	290	172	10	77	354	301	559	2e-11	77.0
rs:WP_016644692	DNA topoisomerase 1 [Streptomyces aurantiacus].	26.04	288	174	9	77	354	299	557	2e-11	77.0
rs:WP_034491437	DNA topoisomerase I [Afifella pfennigii].	24.71	425	234	17	70	452	254	634	2e-11	77.0
rs:WP_019130607	DNA topoisomerase I [Bacteroidales bacterium ph8].	26.35	296	185	7	47	340	221	485	2e-11	76.6
rs:WP_027753040	DNA topoisomerase I [Streptomyces sp. CNH099].	26.64	304	180	11	60	351	281	553	2e-11	77.0
rs:WP_033443240	DNA topoisomerase I, partial [Saccharothrix sp. NRRL B-16314].	25.27	364	220	11	37	377	245	579	2e-11	77.0
rs:WP_026417636	DNA topoisomerase I [Actinoalloteichus cyanogriseus].	25.38	394	233	14	38	409	244	598	2e-11	77.0
rs:WP_031743970	DNA topoisomerase I, partial [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	252	603	2e-11	76.6
rs:WP_013796385	topoisomerase I [Marinomonas posidonica].	24.87	374	233	10	38	401	255	590	2e-11	77.0
rs:WP_014374438	DNA topoisomerase I [Blastococcus saxobsidens].	25.34	367	225	12	42	387	290	628	2e-11	77.0
rs:WP_033756196	DNA topoisomerase I [Helicobacter pylori].	25.57	395	230	17	74	450	251	599	2e-11	76.6
rs:WP_000681497	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	2e-11	76.6
rs:WP_007520053	DNA topoisomerase III [Streptococcus tigurinus].	23.08	377	230	12	19	385	236	562	2e-11	76.6
rs:WP_012870088	DNA topoisomerase I [Thermanaerovibrio acidaminovorans].	24.66	438	254	16	40	452	258	644	2e-11	76.6
tr:A0A0D7BWQ8_9HOMO	SubName: Full=Prokaryotic type I DNA topoisomerase {ECO:0000313|EMBL:KIY74081.1};	25.14	350	202	9	54	385	275	582	2e-11	77.0
rs:WP_047012081	DNA topoisomerase I [Spongiibacter sp. IMCC21906].	23.76	425	256	13	49	452	268	645	2e-11	77.0
rs:WP_033596589	DNA topoisomerase I [Helicobacter pylori].	24.24	396	234	16	74	450	251	599	2e-11	76.6
rs:WP_041836514	DNA topoisomerase I [Actinosynnema mirum].	26.05	357	217	12	38	377	246	572	2e-11	77.0
rs:WP_029795501	DNA topoisomerase I [Vibrio parahaemolyticus].	24.54	379	236	13	77	446	291	628	2e-11	77.0
rs:WP_013247607	DNA topoisomerase I [Candidatus Nitrospira defluvii].	25.39	449	255	21	47	452	229	640	2e-11	76.6
rs:WP_046971205	DNA topoisomerase I [Dyella japonica].	28.03	346	192	15	45	371	233	540	2e-11	77.0
tr:Q0RBI4_FRAAA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.07	326	197	11	77	387	349	645	2e-11	77.0
rs:WP_027122666	DNA topoisomerase I [Mycoplasma spumans].	25.45	385	199	18	92	450	271	593	2e-11	76.6
rs:WP_045586691	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	2e-11	77.0
rs:WP_017448270	topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	2e-11	77.0
rs:WP_025557280	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	2e-11	77.0
rs:WP_030367305	DNA topoisomerase I [Streptomyces roseoverticillatus].	26.28	293	167	11	77	354	301	559	2e-11	77.0
tr:F4WE22_ACREC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.45	364	219	13	37	385	255	577	2e-11	77.0
rs:WP_008898159	topoisomerase I [Rheinheimera sp. A13L].	24.54	379	219	10	1	356	195	529	2e-11	77.0
rs:WP_038658773	MULTISPECIES: DNA topoisomerase I [Enterobacteriaceae].	24.23	421	260	15	40	446	249	624	2e-11	77.0
rs:WP_047207904	DNA topoisomerase I [Campylobacter lari].	24.94	393	229	16	77	450	255	600	2e-11	76.6
rs:WP_010991808	TraB protein [uncultured bacterium].	25.19	401	248	14	70	459	252	611	2e-11	76.6
rs:WP_015643269	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	2e-11	76.6
rs:WP_047043504	DNA topoisomerase I [Vibrio sp. CAIM 1540].	26.18	401	224	16	69	446	276	627	2e-11	77.0
rs:WP_035966600	DNA topoisomerase I [Bradyrhizobium sp. YR681].	23.64	423	260	13	61	452	244	634	2e-11	77.0
rs:WP_021175304	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	2e-11	76.6
rs:WP_009228558	DNA topoisomerase I [Prevotella sp. oral taxon 299].	25.50	349	208	13	77	411	252	562	2e-11	76.6
rs:WP_039918361	DNA topoisomerase I, partial [Synergistes sp. 3_1_syn1].	25.97	412	229	16	66	452	242	602	2e-11	76.6
rs:WP_024421569	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	2e-11	76.6
tr:A0A0D2D362_9EURO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.60	356	223	11	39	377	258	581	2e-11	76.6
rs:WP_001730851	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	26.83	287	176	8	166	446	65	323	2e-11	76.3
rs:WP_006669315	DNA topoisomerase I [Arthrospira maxima].	25.83	333	200	11	25	344	230	528	2e-11	77.0
rs:WP_035759138	MULTISPECIES: DNA topoisomerase I [Arthrospira].	25.83	333	200	11	25	344	230	528	2e-11	77.0
rs:WP_006943967	DNA topoisomerase I [Dermacoccus sp. Ellin185].	26.65	379	224	13	31	387	239	585	2e-11	77.0
rs:WP_026753684	DNA topoisomerase I [Sediminibacter sp. Hel_I_10].	28.52	263	148	9	77	334	249	476	2e-11	76.6
rs:WP_031700735	DNA topoisomerase 1 [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	271	622	2e-11	77.0
rs:WP_044082957	DNA topoisomerase I, partial [Mycobacterium bovis].	25.33	383	231	11	41	399	33	384	2e-11	76.6
rs:WP_010318059	DNA topoisomerase I [Synechococcus sp. CB0205].	26.35	353	219	10	30	370	237	560	2e-11	76.6
rs:WP_022317494	MULTISPECIES: DNA topoisomerase [Prevotella].	25.39	319	186	8	30	334	207	487	2e-11	76.6
rs:WP_015294569	DNA topoisomerase I TopA (Omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) (Nicking-closing enzyme) (TOPO I) [Mycobacterium canettii].	25.33	383	231	11	41	399	271	622	2e-11	77.0
rs:WP_009789155	DNA topoisomerase I [Synechococcus sp. BL107].	26.12	356	219	10	26	370	233	555	2e-11	76.6
tr:J3CRJ2_9BRAD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952}; Flags: Precursor;	23.64	423	260	13	61	452	269	659	2e-11	77.0
rs:WP_021902669	DNA topoisomerase [Porphyromonas sp. CAG:1061].	27.00	263	158	7	77	337	249	479	2e-11	76.6
rs:WP_046767175	DNA topoisomerase I, partial [Jiangella alkaliphila].	28.08	317	184	11	77	379	298	584	2e-11	76.6
tr:Q2W9I9_MAGSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.56	418	239	14	70	454	255	637	2e-11	76.6
rs:WP_045970886	DNA topoisomerase I [Xenorhabdus doucetiae].	26.46	393	229	16	77	452	284	633	2e-11	76.6
rs:WP_014143594	DNA topoisomerase I [Streptomyces cattleya].	24.66	365	218	14	77	422	300	626	2e-11	77.0
rs:WP_021665548	DNA topoisomerase I [Porphyromonas gingivalis].	27.51	269	153	8	77	338	248	481	2e-11	76.6
rs:WP_022835723	DNA topoisomerase I [Salisaeta longa].	24.86	370	225	10	41	387	254	593	2e-11	76.6
rs:XP_011051090	PREDICTED: DNA topoisomerase 3-beta-1 [Acromyrmex echinatior].	24.45	364	219	13	37	385	258	580	2e-11	76.6
rs:WP_043743329	DNA topoisomerase I [Magnetospirillum magneticum].	26.56	418	239	14	70	454	253	635	2e-11	76.6
rs:WP_044097512	DNA topoisomerase I, partial [Mycobacterium canettii].	25.33	383	231	11	41	399	22	373	2e-11	76.6
rs:XP_011326353	hypothetical protein FGSG_06716 [Fusarium graminearum PH-1].	25.23	333	201	10	18	339	232	527	2e-11	76.6
rs:WP_030359673	MULTISPECIES: DNA topoisomerase I [Streptomyces].	25.94	293	168	11	77	354	299	557	2e-11	76.6
rs:WP_013231643	DNA topoisomerase I [Leuconostoc gelidum].	22.37	438	225	16	60	452	261	628	2e-11	76.6
rs:WP_006949726	DNA topoisomerase I [Prevotella marshii].	27.00	263	155	8	77	334	252	482	2e-11	76.6
rs:WP_004916145	DNA topoisomerase I [Riemerella anatipestifer].	28.07	285	164	9	77	352	248	500	2e-11	76.6
rs:WP_014746067	DNA topoisomerase I [Tistrella mobilis].	25.42	417	244	14	70	454	253	634	2e-11	76.6
rs:WP_006915168	DNA topoisomerase I [Salinisphaera shabanensis].	27.27	352	208	11	45	377	233	555	2e-11	76.6
tr:J9FCG0_9SPIT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.14	319	189	11	71	375	808	1087	2e-11	77.0
rs:WP_013545113	DNA topoisomerase I [Bartonella clarridgeiae].	27.36	424	235	19	67	452	248	636	2e-11	76.6
gp:FJ666348_34	TraB [Synthetic plasmid pMOL98]	25.19	401	248	14	70	459	252	611	2e-11	76.6
rs:WP_022164626	DNA topoisomerase [Eubacterium sp. CAG:192].	23.33	433	264	14	48	457	225	612	2e-11	76.6
rs:WP_021114792	DNA topoisomerase I [Haemophilus parasuis].	26.50	283	171	8	77	356	292	540	2e-11	76.6
rs:WP_016519476	DNA topoisomerase I [Treponema vincentii].	22.57	421	268	12	49	452	239	618	2e-11	76.6
rs:WP_024133601	hypothetical protein [Salmonella enterica].	26.83	287	176	8	166	446	60	318	2e-11	76.3
tr:W5VU31_SALTM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AHH86158.1}; Flags: Fragment;	32.09	134	81	3	314	443	3	130	2e-11	73.2
rs:WP_025778061	DNA topoisomerase I [Brevibacterium sp. VCM10].	27.19	331	197	10	41	356	255	556	2e-11	76.6
rs:XP_009156664	DNA topoisomerase III [Exophiala dermatitidis NIH/UT8656].	23.34	377	235	11	41	395	261	605	2e-11	76.3
rs:WP_047316417	DNA topoisomerase I [Mycobacterium haemophilum].	24.87	382	235	11	41	399	280	632	2e-11	76.6
rs:WP_016370883	DNA topoisomerase I, partial [Lactobacillus paracasei].	23.35	424	259	11	43	444	223	602	2e-11	76.3
rs:WP_032568790	DNA topoisomerase I [Bacteroides fragilis].	24.62	264	159	7	77	334	253	482	2e-11	76.6
rs:WP_033603498	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	17	74	450	251	599	2e-11	76.6
rs:WP_024116083	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	2e-11	76.6
rs:WP_046655876	DNA topoisomerase I [Helicobacter pylori].	25.76	396	228	17	74	450	251	599	2e-11	76.6
rs:XP_012052037	DNA topoisomerase III [Cryptococcus neoformans var. grubii H99].	25.78	287	174	7	73	354	299	551	2e-11	76.6
rs:XP_010484154	PREDICTED: DNA topoisomerase 3-alpha-like [Camelina sativa].	22.95	475	280	15	18	451	243	672	2e-11	76.6
tr:C6WFC8_ACTMD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.05	357	217	12	38	377	266	592	2e-11	76.6
rs:WP_033097900	DNA topoisomerase I [Rhodococcus sp. p52].	26.49	336	200	10	35	354	266	570	2e-11	76.6
rs:WP_015157793	DNA topoisomerase I [Chamaesiphon minutus].	23.96	359	230	10	40	387	249	575	2e-11	76.6
rs:WP_022053984	DNA topoisomerase [Bacteroides plebeius CAG:211].	27.41	270	155	8	77	340	249	483	2e-11	76.6
rs:WP_036253930	MULTISPECIES: DNA topoisomerase I, partial [Mesorhizobium].	24.43	442	260	18	45	449	228	632	2e-11	76.6
rs:WP_024918729	DNA topoisomerase I, partial [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	15	366	2e-11	76.6
gpu:CP011883_757	DNA topoisomerase I [Mycobacterium haemophilum DSM 44634]	24.87	382	235	11	41	399	280	632	2e-11	76.6
rs:WP_036886207	DNA topoisomerase I [Prevotella bivia].	24.22	351	188	10	77	382	253	570	2e-11	76.6
rs:WP_013502024	DNA topoisomerase I [Rhodopseudomonas palustris].	24.61	447	263	14	45	454	228	637	2e-11	76.6
rs:WP_029478369	DNA topoisomerase I [Deinococcus frigens].	24.85	326	194	10	36	344	246	537	2e-11	76.6
rs:WP_001921627	DNA topoisomerase I [Helicobacter pylori].	25.57	395	230	17	74	450	251	599	2e-11	76.6
gpu:CP011213_55	topoisomerase I, DNA topoisomerase I protein [Berkelbacteria bacterium GW2011_GWE1_39_12]	24.88	402	249	12	61	454	238	594	2e-11	76.6
rs:WP_029851655	DNA topoisomerase I [Vibrio parahaemolyticus].	26.02	319	191	10	77	385	291	574	2e-11	76.6
rs:WP_005418793	topoisomerase I [Aliivibrio fischeri].	25.72	381	229	14	77	446	289	626	2e-11	76.6
rs:WP_006834330	DNA topoisomerase I [Erythrobacter sp. SD-21].	25.66	339	197	10	41	372	222	512	2e-11	76.6
rs:XP_004989945	DNA topoisomerase [Salpingoeca rosetta].	22.53	435	269	15	40	453	260	647	2e-11	76.6
tr:A0A094QAU3_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KGA21365.1};	26.06	353	211	10	42	377	255	574	2e-11	76.6
rs:WP_029798096	DNA topoisomerase I [Vibrio parahaemolyticus].	24.87	378	236	13	77	446	291	628	2e-11	76.6
rs:WP_013264520	DNA topoisomerase I [Prevotella melaninogenica].	25.94	266	159	7	77	334	252	487	2e-11	76.6
tr:H1WI97_9CYAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.83	333	200	11	25	344	230	528	2e-11	76.6
rs:WP_028830031	DNA topoisomerase I [Proteocatella sphenisci].	22.43	428	270	12	48	457	232	615	2e-11	76.6
rs:WP_021118106	DNA topoisomerase I [Haemophilus parasuis].	26.50	283	171	8	77	356	292	540	2e-11	76.6
tr:F6FHS3_MYCHI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00003390}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.25	466	280	15	1	449	212	621	2e-11	76.6
tr:M7XAM1_RHOT1	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EMS20774.1};	25.39	382	218	14	39	395	261	600	2e-11	76.6
rs:WP_047309161	DNA topoisomerase I [Rhodopseudomonas palustris].	24.61	447	263	14	45	454	228	637	2e-11	76.6
rs:NP_001254382	Y48C3A.14, isoform c [Caenorhabditis elegans].	24.00	475	285	18	12	457	96	523	2e-11	76.6
rs:WP_031663965	DNA topoisomerase I [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	271	622	2e-11	76.6
rs:WP_042759427	DNA topoisomerase I, partial [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	93	444	2e-11	76.6
rs:WP_024900231	DNA topoisomerase I [Ochrobactrum rhizosphaerae].	24.37	439	266	14	47	452	230	635	2e-11	76.6
rs:WP_029861698	DNA topoisomerase I [Vibrio parahaemolyticus].	26.02	319	191	10	77	385	291	574	2e-11	76.6
rs:WP_026916483	DNA topoisomerase I [[Haemophilus] parasuis].	26.50	283	171	8	77	356	292	540	2e-11	76.6
tr:M4E275_BRARP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.00	292	176	10	65	351	283	536	2e-11	76.6
rs:WP_038300223	DNA topoisomerase I, partial [alpha proteobacterium IMCC14465].	23.29	438	256	13	51	454	244	635	2e-11	76.6
rs:XP_009132830	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Brassica rapa].	25.00	292	176	10	65	351	286	539	2e-11	76.6
rs:WP_039958145	DNA topoisomerase I [Rhodococcus pyridinivorans].	26.49	336	200	10	35	354	266	570	2e-11	76.6
rs:WP_025532763	DNA topoisomerase I [Vibrio parahaemolyticus].	26.02	319	191	10	77	385	291	574	2e-11	76.6
rs:WP_006797683	DNA topoisomerase I [Dysgonomonas gadei].	25.95	262	158	6	77	334	252	481	2e-11	76.6
tr:K1W611_ARTPT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.83	333	200	11	25	344	238	536	2e-11	76.6
rs:WP_029400944	DNA topoisomerase I, partial [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	25	376	2e-11	76.3
tr:A0A090N6Z9_AFIFE	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:CEG07733.1};	27.31	249	139	7	223	454	33	256	2e-11	76.3
rs:WP_025577951	DNA topoisomerase I [Vibrio parahaemolyticus].	26.02	319	191	10	77	385	291	574	2e-11	76.6
rs:WP_036921705	DNA topoisomerase I [Prevotella sp. ICM33].	25.94	266	159	7	77	334	252	487	2e-11	76.6
rs:WP_014421722	topoisomerase I [Marinobacter hydrocarbonoclasticus].	24.05	395	254	13	59	446	277	632	2e-11	76.6
rs:WP_003078034	toprim domain / DNA topoisomerase multi-domain protein [Streptococcus intermedius].	23.55	344	227	10	59	397	263	575	2e-11	76.3
rs:WP_038399844	DNA topoisomerase I [Yersinia pseudotuberculosis].	24.21	380	237	13	77	446	290	628	2e-11	76.6
rs:WP_028911148	DNA topoisomerase I [Prevotella sp. MA2016].	26.22	286	164	7	77	345	252	507	2e-11	76.6
rs:WP_024102825	DNA topoisomerase I [Rhodococcus pyridinivorans].	26.49	336	200	10	35	354	258	562	2e-11	76.6
rs:WP_044081809	DNA topoisomerase I, partial [Mycobacterium canettii].	25.33	383	231	11	41	399	27	378	2e-11	76.3
rs:WP_031648458	DNA topoisomerase I [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	271	622	2e-11	76.6
rs:WP_024456515	DNA topoisomerase I, partial [Mycobacterium bovis].	25.33	383	231	11	41	399	5	356	2e-11	76.3
rs:WP_033768917	DNA topoisomerase I [Helicobacter pylori].	24.75	396	232	16	74	450	251	599	2e-11	76.3
tr:X3YJZ4_SALEN	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:AHS74663.1}; Flags: Fragment;	29.74	195	107	6	166	356	27	195	2e-11	73.2
rs:WP_037272240	DNA topoisomerase I [Roseovarius mucosus].	25.27	467	259	20	41	454	225	654	2e-11	76.6
rs:WP_016340453	DNA topoisomerase I [Spiroplasma syrphidicola].	24.51	408	245	12	61	450	233	595	2e-11	76.3
rs:WP_037975704	DNA topoisomerase I [Synergistes jonesii].	25.49	408	237	14	65	452	325	685	2e-11	76.3
rs:WP_000681469	DNA topoisomerase I [Helicobacter pylori].	25.32	395	231	17	74	450	251	599	2e-11	76.3
rs:WP_014203113	DNA topoisomerase I [Owenweeksia hongkongensis].	26.54	260	158	6	77	334	249	477	2e-11	76.6
rs:WP_010196278	topoisomerase I [Psychrobacter sp. PAMC 21119].	25.62	363	208	15	40	384	270	588	2e-11	76.6
tr:F5NTM5_SHIFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.83	287	176	8	166	446	60	318	2e-11	76.3
rs:WP_011192446	topoisomerase I [Yersinia pseudotuberculosis].	24.67	381	234	14	77	446	290	628	2e-11	76.6
rs:WP_009842753	topoisomerase I [Vibrio sp. AND4].	25.13	386	225	13	77	446	291	628	2e-11	76.6
tr:A0A0A8HWB1_CAMLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.94	393	229	16	77	450	254	599	2e-11	76.3
rs:WP_002274518	DNA topoisomerase I, partial [Streptococcus mutans].	24.75	295	179	8	166	452	24	283	2e-11	75.1
rs:WP_011143190	DNA topoisomerase I [Gloeobacter violaceus].	28.09	235	129	8	228	453	416	619	2e-11	76.3
rs:XP_003687892	hypothetical protein TPHA_0L01010 [Tetrapisispora phaffii CBS 4417].	24.77	331	192	9	50	357	289	585	2e-11	76.3
rs:WP_011799364	MULTISPECIES: DNA topoisomerase I [Mycobacterium tuberculosis complex].	25.33	383	231	11	41	399	271	622	2e-11	76.6
rs:WP_039625170	DNA topoisomerase I [Campylobacter lari].	24.94	393	229	16	77	450	255	600	2e-11	76.3
rs:WP_036864134	DNA topoisomerase I [Prevotella bivia].	24.34	267	162	6	77	334	253	488	2e-11	76.3
rs:XP_007266922	prokaryotic type I DNA topoisomerase [Fomitiporia mediterranea MF3/22].	25.27	376	219	13	40	393	269	604	2e-11	76.6
rs:WP_043098176	DNA topoisomerase I, partial [bacterium JKG1].	25.42	421	254	16	50	445	234	619	2e-11	76.3
rs:WP_004336816	DNA topoisomerase I [Prevotella bivia].	24.34	267	162	6	77	334	253	488	2e-11	76.3
sp:TOP1_HELPJ	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.76	396	228	17	74	450	251	599	2e-11	76.3
rs:WP_034371259	DNA topoisomerase I, partial [Helicobacter sp. MIT 05-5293].	23.74	417	244	14	41	431	218	586	2e-11	76.3
tr:A0A034TJM3_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.56	320	189	11	77	385	292	576	2e-11	76.6
rs:WP_003419640	DNA topoisomerase I subunit omega [Mycobacterium orygis].	25.33	383	231	11	41	399	271	622	2e-11	76.6
rs:WP_038514169	DNA topoisomerase I [[Haemophilus] parasuis].	27.11	284	168	10	77	356	292	540	2e-11	76.6
rs:WP_013604174	DNA topoisomerase [Vulcanisaeta moutnovskia].	23.51	336	198	9	35	354	247	539	2e-11	76.3
rs:WP_025796144	DNA topoisomerase I [Vibrio parahaemolyticus].	26.02	319	191	10	77	385	291	574	2e-11	76.6
rs:WP_029156120	MULTISPECIES: DNA topoisomerase I [unclassified Cloacimonetes].	23.52	421	264	14	47	451	227	605	2e-11	76.3
rs:WP_037760867	DNA topoisomerase I [Streptomyces olindensis].	25.94	293	168	11	77	354	299	557	2e-11	76.6
tr:J9CX79_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EJX04866.1};	24.69	320	186	8	47	345	216	501	2e-11	76.3
rs:WP_019281959	topoisomerase I [Vibrio anguillarum].	23.98	392	244	14	69	446	277	628	2e-11	76.6
rs:WP_017346259	topoisomerase I [Pantoea sp. A4].	26.63	323	185	12	77	385	284	568	2e-11	76.3
rs:WP_043607218	DNA topoisomerase I [Cellulomonas carbonis].	26.35	353	202	11	35	356	243	568	2e-11	76.6
tr:J9DEH1_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.29	438	256	13	51	454	244	635	2e-11	76.3
rs:WP_012692721	DNA topoisomerase I [Deinococcus deserti].	25.16	322	190	10	40	344	250	537	2e-11	76.6
rs:WP_024458145	DNA topoisomerase I, partial [Mycobacterium bovis].	25.33	383	231	11	41	399	9	360	2e-11	76.3
tr:K6JEI1_KLEOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKP25391.1};	40.86	93	55	0	293	385	1	93	2e-11	72.0
rs:WP_021588432	DNA topoisomerase I [Prevotella baroniae].	26.37	364	216	13	59	411	237	559	2e-11	76.3
rs:WP_014215391	DNA topoisomerase I [Pediococcus claussenii].	23.46	422	237	18	61	452	242	607	2e-11	76.3
rs:WP_037217231	DNA topoisomerase I [Rhodococcus sp. R04].	26.49	336	200	10	35	354	266	570	2e-11	76.6
rs:WP_031649026	DNA topoisomerase I [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	271	622	2e-11	76.6
tr:A0A087TZV0_9ARAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.66	317	199	10	85	393	3	284	2e-11	75.9
rs:XP_002140607	DNA topoisomerase family protein [Cryptosporidium muris RN66].	23.72	333	191	10	65	379	311	598	2e-11	76.3
tr:G9PXX1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.97	412	229	16	66	452	321	681	2e-11	76.3
gp:CP007776_154	DNA topoisomerase I [Campylobacter lari CCUG 22395]	24.94	393	229	16	77	450	254	599	2e-11	76.3
rs:WP_038569546	DNA topoisomerase I [Dermacoccus nishinomiyaensis].	26.39	379	225	13	31	387	239	585	2e-11	76.6
rs:WP_016666857	DNA topoisomerase I [Propionibacterium sp. HGH0353].	25.79	380	224	16	35	388	243	590	2e-11	76.6
tr:A0A0D2GQU9_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.59	426	258	17	47	452	228	614	2e-11	76.3
tr:H0JSA9_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.49	336	200	10	35	354	258	562	2e-11	76.6
rs:WP_039586736	DNA topoisomerase I [Rhodococcus sp. Chr-9].	26.49	336	200	10	35	354	258	562	2e-11	76.6
rs:XP_009132831	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Brassica rapa].	25.00	292	176	10	65	351	259	512	2e-11	76.3
tr:D3I2I7_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.94	266	159	7	77	334	254	489	2e-11	76.3
rs:WP_038176919	DNA topoisomerase I [Vibrio pacinii].	24.30	391	244	11	69	446	276	627	2e-11	76.3
rs:WP_003846154	DNA topoisomerase I [Corynebacterium ammoniagenes].	26.59	331	183	14	34	354	270	550	2e-11	76.6
rs:WP_035603017	DNA topoisomerase I [Edwardsiella tarda].	26.01	323	189	10	77	386	284	569	2e-11	76.3
rs:XP_956391	DNA topoisomerase 3-beta [Neurospora crassa OR74A].	25.09	283	168	7	61	336	308	553	2e-11	76.3
rs:WP_041438427	hypothetical protein, partial [Thermodesulfobium narugense].	23.04	434	269	11	40	454	221	608	2e-11	76.3
rs:WP_003144692	DNA topoisomerase I [Gemella haemolysans].	22.61	429	260	12	47	452	225	604	2e-11	76.3
rs:WP_031678190	DNA topoisomerase I [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	271	622	2e-11	76.3
rs:WP_044513401	DNA topoisomerase I [Hymenobacter sp. DG25B].	27.84	291	179	8	47	334	219	481	2e-11	76.3
rs:WP_005968653	topoisomerase I [Pectobacterium wasabiae].	24.81	399	244	13	61	446	268	623	2e-11	76.3
tr:E8ZK73_MYCHL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00003390}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.25	466	280	15	1	449	212	621	2e-11	76.3
tr:A0A090S351_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	25.19	393	241	14	65	446	73	423	2e-11	76.3
rs:WP_024356505	DNA topoisomerase I [Leucobacter chironomi].	27.86	323	185	13	77	380	295	588	2e-11	76.3
rs:XP_003104074	CRE-TOP-3 protein [Caenorhabditis remanei].	24.72	360	201	11	39	377	260	570	2e-11	76.3
rs:WP_041771013	DNA topoisomerase I, partial [Liberibacter crescens].	23.08	442	269	16	47	452	230	636	2e-11	76.3
rs:WP_032763519	DNA topoisomerase I, partial [Lactobacillus paracasei].	25.71	245	147	7	212	452	21	234	2e-11	74.3
rs:WP_040730058	DNA topoisomerase I [Nocardia tenerifensis].	25.08	331	202	10	41	356	271	570	2e-11	76.3
rs:WP_012628662	DNA topoisomerase I [Cyanothece sp. PCC 7425].	26.12	356	214	12	36	377	250	570	2e-11	76.3
rs:WP_015783361	DNA topoisomerase I [Cyanothece sp. PCC 8802].	24.57	346	226	9	41	379	249	566	2e-11	76.3
rs:WP_029403025	DNA topoisomerase I, partial [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	29	380	2e-11	76.3
rs:WP_036885723	DNA topoisomerase I [Prevotella melaninogenica].	25.94	266	159	7	77	334	252	487	2e-11	76.3
rs:WP_012054374	DNA topoisomerase 1 [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	271	622	2e-11	76.3
rs:WP_039627787	DNA topoisomerase I [Campylobacter lari].	24.94	393	229	16	77	450	255	600	3e-11	76.3
tr:K1VYW4_TRIAC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EKD04732.1};	26.04	288	158	9	73	354	253	491	3e-11	76.6
tr:A0A0E8TQT5_STREE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CRG02990.1};	30.82	146	94	4	311	454	2	142	3e-11	72.8
rs:WP_004373408	DNA topoisomerase I [Prevotella oris].	24.68	308	197	7	30	334	207	482	3e-11	76.3
rs:WP_031684172	DNA topoisomerase I [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	268	619	3e-11	76.3
rs:WP_003905122	DNA topoisomerase 1 [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	271	622	3e-11	76.3
rs:WP_039211367	DNA topoisomerase I [Brevibacterium linens].	26.89	331	198	11	41	356	255	556	3e-11	76.3
rs:WP_027629548	DNA topoisomerase I [[Clostridium] cellobioparum].	25.38	398	239	12	77	452	256	617	3e-11	76.3
gpu:CP010855_525	76.6	25.21	468	243	18	48	454	242	663	3e-11
rs:WP_011421751	DNA topoisomerase I [Anaeromyxobacter dehalogenans].	23.20	444	263	15	49	452	273	678	3e-11	76.3
sp:TOP1_MYCBO	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.33	383	231	11	41	399	271	622	3e-11	76.3
rs:WP_004049062	DNA topoisomerase I [Halorubrum saccharovorum].	23.50	468	270	18	35	454	242	669	3e-11	76.3
rs:WP_034165152	MULTISPECIES: DNA topoisomerase I [Edwardsiella].	24.69	320	197	9	77	386	284	569	3e-11	76.3
tr:U1EIY6_ENTGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.15	330	188	13	70	377	1	293	3e-11	74.3
rs:WP_025880938	DNA topoisomerase I [Prevotella baroniae].	26.37	364	216	13	59	411	237	559	3e-11	76.3
rs:WP_004028404	DNA topoisomerase I [Spiroplasma melliferum].	24.88	410	242	14	60	450	232	594	3e-11	76.3
rs:WP_009380839	DNA topoisomerase I [Brevibacterium casei].	25.53	376	229	12	41	394	255	601	3e-11	76.3
rs:WP_018919763	DNA topoisomerase I [Prevotella oris].	26.05	261	160	6	77	334	252	482	3e-11	76.3
rs:WP_012659505	DNA topoisomerase I [Halorubrum lacusprofundi].	23.77	467	270	18	35	454	242	669	3e-11	76.3
rs:WP_023792924	hypothetical protein [candidate division SR1 bacterium RAAC1_SR1_1].	25.94	293	180	8	47	335	219	478	3e-11	76.3
rs:WP_001926900	DNA topoisomerase I [Helicobacter pylori].	25.32	395	231	17	74	450	251	599	3e-11	76.3
rs:WP_000681434	DNA topoisomerase I [Helicobacter pylori].	24.75	396	232	16	74	450	251	599	3e-11	76.3
rs:WP_029238789	DNA topoisomerase I, partial [Streptococcus sobrinus].	23.30	352	200	11	50	377	254	559	3e-11	75.9
rs:WP_031696707	DNA topoisomerase 1 [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	271	622	3e-11	76.3
tr:V2BAJ7_SALET	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.88	269	155	10	77	341	284	517	3e-11	75.9
tr:I6HI63_SHIFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.83	287	176	8	166	446	60	318	3e-11	75.9
rs:WP_015637930	DNA topoisomerase I [Candidatus Phytoplasma australiense].	22.99	435	260	15	42	454	212	593	3e-11	75.9
rs:WP_000237218	DNA topoisomerase III [Streptococcus sp. oral taxon 071].	23.73	354	222	12	44	385	245	562	3e-11	75.9
rs:XP_005807446	PREDICTED: DNA topoisomerase 3-beta-1-like [Xiphophorus maculatus].	22.68	441	261	15	40	453	263	650	3e-11	76.3
rs:WP_028799128	DNA topoisomerase I [Streptomyces sp. 142MFCol3.1].	26.39	288	173	9	77	354	299	557	3e-11	76.3
tr:A0A0E4BD43_TANFO	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:BAR49021.1};	25.87	344	216	11	65	384	241	569	3e-11	76.3
rs:WP_020141292	DNA topoisomerase I [Streptomyces sp. 351MFTsu5.1].	25.94	293	168	11	77	354	299	557	3e-11	76.3
rs:WP_030324007	DNA topoisomerase I [Streptomyces sp. NRRL B-3229].	25.94	293	168	11	77	354	299	557	3e-11	76.3
rs:WP_033620616	DNA topoisomerase I [Helicobacter pylori].	24.49	396	233	16	74	450	251	599	3e-11	76.3
rs:WP_033599198	DNA topoisomerase I [Helicobacter pylori].	25.25	396	230	17	74	450	251	599	3e-11	76.3
rs:WP_026061366	DNA topoisomerase I [Rhodococcus rhodochrous].	26.49	336	200	10	35	354	258	562	3e-11	76.3
rs:WP_004029070	DNA topoisomerase I [Spiroplasma melliferum].	24.88	410	242	14	60	450	232	594	3e-11	75.9
rs:WP_031697198	DNA topoisomerase I [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	271	622	3e-11	76.3
rs:WP_032407549	topoisomerase I [Rhodococcus fascians].	27.51	378	195	17	79	439	284	599	3e-11	76.3
rs:WP_033745323	DNA topoisomerase I [Helicobacter pylori].	25.25	396	230	17	74	450	251	599	3e-11	76.3
rs:WP_015427359	DNA topoisomerase I [Helicobacter pylori].	24.75	396	232	17	74	450	251	599	3e-11	76.3
rs:WP_020185324	hypothetical protein [Methylopila sp. 73B].	24.78	460	260	17	39	454	221	638	3e-11	76.3
rs:XP_002181586	predicted protein [Phaeodactylum tricornutum CCAP 1055/1].	24.14	319	211	8	39	353	336	627	3e-11	76.3
gpu:CP011215_450	topoisomerase I, DNA topoisomerase I protein [Parcubacteria (Campbellbacteria) bacterium GW2011_OD1_34_28]	25.55	411	245	16	56	449	233	599	3e-11	76.3
rs:WP_044096153	DNA topoisomerase I, partial [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	166	517	3e-11	76.3
rs:WP_047547776	DNA topoisomerase I [Microbacterium sp. CF335].	27.46	346	199	11	46	377	261	568	3e-11	76.3
rs:WP_047008550	MULTISPECIES: DNA topoisomerase I [Vibrio].	25.33	379	233	14	77	446	291	628	3e-11	76.3
rs:WP_022103541	DNA topoisomerase [Bacteroides stercoris CAG:120].	35.00	120	76	2	278	396	17	135	3e-11	73.2
rs:WP_031676706	DNA topoisomerase 1 [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	271	622	3e-11	76.3
rs:WP_015291611	DNA topoisomerase I TopA (Omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) (Nicking-closing enzyme) (TOPO I) [Mycobacterium canettii].	25.33	383	231	11	41	399	271	622	3e-11	76.3
rs:WP_026066374	DNA topoisomerase I [Actinoalloteichus spitiensis].	26.43	367	208	15	66	409	294	621	3e-11	76.3
rs:WP_034443192	DNA topoisomerase I [Cloacibacillus evryensis].	25.97	412	229	16	66	452	321	681	3e-11	76.3
rs:WP_031658525	DNA topoisomerase I [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	271	622	3e-11	76.3
rs:WP_046825087	DNA topoisomerase I [Tannerella forsythia].	25.87	344	216	11	65	384	241	569	3e-11	76.3
rs:WP_021758054	DNA topoisomerase I [Leifsonia aquatica].	28.69	373	212	15	30	379	238	579	3e-11	76.3
tr:T0E7D5_CLOSO	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EPZ59488.1};	31.58	152	78	3	276	425	4	131	3e-11	73.2
rs:WP_033750475	DNA topoisomerase I [Helicobacter pylori].	25.25	396	230	17	74	450	251	599	3e-11	76.3
rs:WP_000681487	DNA topoisomerase I [Helicobacter pylori].	24.56	395	234	16	74	450	251	599	3e-11	76.3
rs:WP_028685782	DNA topoisomerase I [Phaseolibacter flectens].	25.13	394	233	15	77	452	284	633	3e-11	76.3
rs:WP_033776699	DNA topoisomerase I [Helicobacter pylori].	24.56	395	234	16	74	450	251	599	3e-11	76.3
rs:WP_025309579	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	17	74	450	251	599	3e-11	76.3
rs:WP_038134722	DNA topoisomerase I [Thiomicrospira sp. Milos-T1].	27.76	281	158	9	60	334	236	477	3e-11	76.3
rs:XP_001209597	DNA topoisomerase III [Aspergillus terreus NIH2624].	28.42	278	143	8	98	358	280	518	3e-11	75.9
tr:M1E7D1_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.04	434	269	11	40	454	221	608	3e-11	75.9
rs:WP_025630849	DNA topoisomerase I [Vibrio parahaemolyticus].	25.33	379	233	14	77	446	291	628	3e-11	76.3
tr:V5GHF3_PSEBG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.05	311	175	11	60	357	884	1152	3e-11	76.3
rs:WP_023104167	hypothetical protein, partial [Pseudomonas aeruginosa].	25.08	299	170	10	186	459	7	276	3e-11	73.9
rs:WP_022331603	DNA topoisomerase [Firmicutes bacterium CAG:345].	23.76	442	250	13	61	450	235	641	3e-11	75.9
rs:WP_022076495	DNA topoisomerase [Clostridium sp. CAG:571].	22.98	322	204	8	47	356	226	515	3e-11	75.9
rs:WP_013447026	DNA topoisomerase I [Riemerella anatipestifer].	28.07	285	164	9	77	352	248	500	3e-11	76.3
tr:L0EVH2_LIBCB	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.08	442	269	16	47	452	230	636	3e-11	76.3
rs:WP_004378157	DNA topoisomerase I [Prevotella oris].	25.00	308	196	7	30	334	207	482	3e-11	76.3
rs:WP_036953684	DNA topoisomerase I [Promicromonosporaceae bacterium W15].	25.67	335	202	11	42	356	259	566	3e-11	76.3
rs:WP_007288449	DNA topoisomerase I [Thermosinus carboxydivorans].	23.43	431	268	14	47	457	226	614	3e-11	75.9
tr:J7SJ75_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.77	428	262	14	49	457	257	643	3e-11	76.3
rs:WP_019943304	DNA topoisomerase I [Dyadobacter beijingensis].	27.64	275	164	9	68	340	242	483	3e-11	76.3
tr:A0A0F3ARS2_SALET	SubName: Full=DNA topoisomerase I subunit omega {ECO:0000313|EMBL:KJT96499.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KJT96499.1};	27.88	269	155	10	77	341	284	517	3e-11	75.9
rs:WP_033770665	DNA topoisomerase I [Helicobacter pylori].	25.25	396	230	17	74	450	251	599	3e-11	75.9
rs:WP_048494469	DNA topoisomerase I [Marinobacter sp. JG233].	23.79	391	248	13	68	446	281	633	3e-11	76.3
rs:WP_037365465	DNA topoisomerase I [Selenomonas sp. FOBRC6].	25.49	412	246	15	65	457	288	657	3e-11	76.3
rs:WP_038898164	DNA topoisomerase I [Vibrio harveyi].	25.26	380	232	13	77	446	291	628	3e-11	76.3
tr:T0ZRV5_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD47393.1}; Flags: Fragment;	39.80	98	57	2	36	133	59	154	3e-11	72.0
rs:WP_013670801	DNA topoisomerase I [Prevotella denticola].	25.34	292	166	9	77	350	252	509	3e-11	75.9
rs:WP_022008889	DNA topoisomerase [Firmicutes bacterium CAG:646].	22.82	425	276	10	48	457	227	614	3e-11	75.9
rs:WP_021300989	DNA topoisomerase I [Helicobacter pylori].	24.56	395	234	16	74	450	251	599	3e-11	75.9
rs:WP_021104027	DNA topoisomerase I, partial [Propionibacterium granulosum].	26.23	324	188	13	77	379	6	299	3e-11	75.9
rs:WP_043900714	hypothetical protein, partial [Parcubacteria bacterium RAAC4_OD1_1].	23.35	471	295	15	2	449	173	600	3e-11	75.9
tr:O53042_HELPX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	396	231	16	74	450	251	599	3e-11	75.9
tr:A0A0D0UDH7_CRYGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.44	287	175	7	73	354	299	551	3e-11	76.3
tr:A0A0E3VR82_TANFO	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:BAR51705.1};	25.87	344	216	11	65	384	241	569	3e-11	75.9
rs:WP_027493257	DNA topoisomerase I [Rhodanobacter sp. OR444].	26.53	343	202	12	60	380	247	561	3e-11	75.9
rs:WP_039434731	DNA topoisomerase I [Porphyromonas gulae].	27.82	266	155	8	77	338	248	480	3e-11	75.9
tr:A0A090CU18_PODAN	SubName: Full=Putative DNA topoisomerase 3 {ECO:0000313|EMBL:CDP32445.1};	24.76	315	177	9	37	335	255	525	3e-11	75.9
rs:WP_014231327	MULTISPECIES: topoisomerase I [Vibrio].	26.05	380	229	16	77	446	290	627	3e-11	76.3
rs:WP_017282916	DNA topoisomerase I [Helicobacter pylori].	24.56	395	234	16	74	450	251	599	3e-11	75.9
rs:WP_016595154	topoisomerase I, partial [Yersinia pestis].	24.11	365	228	11	77	431	290	615	3e-11	75.9
rs:WP_035122695	DNA topoisomerase I [Corynebacterium freneyi].	23.14	389	250	10	41	409	262	621	3e-11	76.3
rs:WP_033935563	DNA topoisomerase I [Lactobacillus mucosae].	22.81	434	261	14	43	452	257	640	3e-11	75.9
tr:K1SQ13_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EKC55950.1}; Flags: Fragment;	30.35	201	114	3	166	362	3	181	3e-11	72.4
rs:WP_025766918	DNA topoisomerase I [Vibrio parahaemolyticus].	26.56	320	188	11	77	385	291	574	3e-11	75.9
rs:WP_018845833	DNA topoisomerase I [Streptomyces sp. CNT372].	25.94	293	168	11	77	354	299	557	3e-11	76.3
rs:WP_014118434	DNA topoisomerase I [Oscillibacter valericigenes].	24.52	420	258	14	55	454	236	616	3e-11	75.9
rs:WP_019791054	DNA topoisomerase I, partial [Streptococcus sobrinus].	23.30	352	200	11	50	377	254	559	3e-11	75.9
tr:K2EKG9_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.37	439	248	18	47	452	225	612	3e-11	75.9
rs:WP_023038729	DNA topoisomerase III [Fusobacterium nucleatum].	23.43	397	243	14	60	431	270	630	3e-11	75.9
tr:A0A0C7BNT0_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.68	342	221	10	18	351	237	546	3e-11	75.9
rs:WP_039310266	DNA topoisomerase I [Pectobacterium atrosepticum].	25.31	399	242	14	61	446	268	623	3e-11	75.9
rs:WP_007101752	DNA topoisomerase I [Synechococcus sp. RS9917].	24.14	377	231	9	37	389	246	591	3e-11	75.9
rs:WP_031721076	DNA topoisomerase I [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	271	622	3e-11	75.9
tr:H2Z242_CIOSA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.28	331	193	11	60	379	281	571	3e-11	75.5
rs:XP_009622051	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Nicotiana tomentosiformis].	26.13	287	161	8	187	452	361	617	3e-11	75.9
rs:WP_009435473	DNA topoisomerase I [Prevotella sp. oral taxon 306].	24.91	269	158	7	77	334	252	487	3e-11	75.9
rs:WP_036129296	DNA topoisomerase I [Marinobacter sp. AK21].	23.40	423	268	12	36	446	255	633	3e-11	75.9
rs:WP_004101613	DNA topoisomerase I [Thermosipho africanus].	24.43	352	210	10	60	392	225	539	3e-11	75.9
rs:WP_007365501	DNA topoisomerase I [Porphyromonas uenonis].	25.67	261	159	6	77	334	253	481	3e-11	75.9
rs:WP_014791168	DNA topoisomerase I [Ornithobacterium rhinotracheale].	26.06	376	224	11	47	411	229	561	3e-11	75.9
rs:XP_011501910	PREDICTED: DNA topoisomerase 3-beta-1 [Ceratosolen solmsi marchali].	23.76	362	223	10	37	385	258	579	3e-11	75.9
rs:WP_000681418	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	3e-11	75.9
rs:WP_008237824	DNA topoisomerase I [Imtechella halotolerans].	25.24	309	188	7	37	334	200	476	3e-11	75.9
rs:WP_019968915	DNA topoisomerase I [Prevotella maculosa].	26.32	266	153	8	77	334	252	482	3e-11	75.9
rs:WP_001931094	DNA topoisomerase I [Helicobacter pylori].	24.49	396	233	16	74	450	251	599	3e-11	75.9
rs:WP_036893779	DNA topoisomerase I [Prevotella sp. S7-1-8].	26.87	268	155	9	77	338	252	484	3e-11	75.9
rs:WP_034017814	hypothetical protein [Pseudomonas aeruginosa].	24.88	410	219	17	70	446	240	593	3e-11	75.9
rs:WP_035527058	DNA topoisomerase I [Haliea salexigens].	23.80	416	248	15	58	452	276	643	3e-11	75.9
tr:A0A078SSG1_9PORP	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:KDS64834.1};	26.14	329	211	9	61	385	234	534	3e-11	75.5
tr:A0A078CQI8_BRANA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.58	318	201	10	40	351	123	404	3e-11	75.9
rs:WP_004382933	DNA topoisomerase I [Prevotella veroralis].	23.90	318	198	8	27	334	204	487	3e-11	75.9
rs:WP_000681415	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	3e-11	75.9
tr:A0A0B4IPU2_VIBHA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	380	233	13	77	446	291	628	3e-11	75.9
rs:WP_005450368	MULTISPECIES: topoisomerase I [Vibrio].	25.00	380	233	13	77	446	291	628	3e-11	75.9
rs:WP_021713044	DNA topoisomerase I [Vibrio ezurae].	24.55	391	221	14	77	446	290	627	3e-11	75.9
rs:XP_005652066	prokaryotic type I DNA topoisomerase [Coccomyxa subellipsoidea C-169].	25.63	398	218	14	40	412	266	610	3e-11	75.9
rs:WP_024949339	DNA topoisomerase I [Helicobacter pylori].	24.56	395	234	16	74	450	251	599	3e-11	75.9
rs:WP_014021586	DNA topoisomerase I [Cyclobacterium marinum].	25.78	287	176	7	68	347	240	496	3e-11	75.9
rs:WP_033321736	DNA topoisomerase I [Streptomyces yerevanensis].	25.94	293	168	11	77	354	299	557	3e-11	75.9
rs:XP_009064575	hypothetical protein LOTGIDRAFT_236127 [Lottia gigantea].	24.30	391	232	13	39	408	266	613	3e-11	75.5
rs:WP_016768417	topoisomerase I [Vibrio cyclitrophicus].	26.37	383	224	15	77	446	290	627	4e-11	75.9
tr:K5U6E8_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	380	233	13	77	446	284	621	4e-11	75.9
rs:WP_040715762	DNA topoisomerase I [Nocardia veterana].	25.78	322	189	10	47	356	272	555	4e-11	75.9
rs:WP_017820029	topoisomerase I [Vibrio alginolyticus].	26.56	320	188	11	77	385	291	574	4e-11	75.9
tr:B9L0B0_THERP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.89	446	217	16	66	457	280	661	4e-11	75.9
tr:H2YRK6_CIOSA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAVP00000007966}; Flags: Fragment;	24.63	268	163	6	167	421	21	262	4e-11	75.1
rs:WP_000681420	DNA topoisomerase I [Helicobacter pylori].	24.56	395	234	16	74	450	251	599	4e-11	75.9
rs:WP_000681417	DNA topoisomerase I [Helicobacter pylori].	25.00	396	231	16	74	450	251	599	4e-11	75.9
rs:WP_042510470	DNA topoisomerase I [Moraxella catarrhalis].	25.63	359	213	17	40	384	263	581	4e-11	75.9
rs:WP_014945419	DNA topoisomerase I [Chlamydia psittaci].	24.49	396	248	17	69	449	263	622	4e-11	75.9
rs:WP_001937468	DNA topoisomerase I [Helicobacter pylori].	25.25	396	230	17	74	450	251	599	4e-11	75.9
rs:XP_001908297	hypothetical protein [Podospora anserina S mat+].	24.76	315	177	8	37	335	340	610	4e-11	75.9
rs:WP_029454711	DNA topoisomerase I [Candidatus Pelagibacter ubique].	24.60	435	261	15	51	454	234	632	4e-11	75.9
rs:WP_042255222	DNA topoisomerase I [Nocardia brasiliensis].	24.77	331	203	9	41	356	271	570	4e-11	75.9
rs:WP_038229594	DNA topoisomerase I [Vibrio sp. ER1A].	26.10	387	233	16	71	446	283	627	4e-11	75.9
rs:WP_017051947	topoisomerase I [Vibrio genomosp. F6].	24.64	422	252	15	42	446	255	627	4e-11	75.9
rs:WP_004248126	topoisomerase I [Proteus mirabilis].	25.96	389	230	16	80	452	287	633	4e-11	75.9
rs:WP_024365688	DNA topoisomerase I [Arthrobacter sp. TB 26].	27.30	326	194	11	77	385	289	588	4e-11	75.9
rs:WP_029447781	MULTISPECIES: DNA topoisomerase I [Cellulophaga].	25.68	292	181	7	47	334	219	478	4e-11	75.9
rs:WP_038029314	DNA topoisomerase I [Thermonema rossianum].	27.70	278	171	8	60	335	233	482	4e-11	75.9
rs:WP_017883608	DNA topoisomerase I [Leucobacter sp. UCD-THU].	27.91	344	196	14	58	380	276	588	4e-11	75.9
rs:WP_036559282	DNA topoisomerase I [Nocardia brasiliensis].	24.77	331	203	9	41	356	271	570	4e-11	75.9
rs:WP_005378351	MULTISPECIES: topoisomerase I [Vibrio].	26.56	320	188	11	77	385	291	574	4e-11	75.9
rs:WP_023641851	DNA topoisomerase I [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	271	622	4e-11	75.9
rs:WP_041563303	DNA topoisomerase I [Nocardia brasiliensis].	24.77	331	203	9	41	356	271	570	4e-11	75.9
rs:WP_004490023	DNA topoisomerase I [Leptospira santarosai].	23.80	437	262	17	40	450	211	602	4e-11	75.5
tr:W4VMX9_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE94542.1};	36.90	84	53	0	160	243	36	119	4e-11	72.0
rs:WP_003672057	topoisomerase I [Moraxella catarrhalis].	25.63	359	213	17	40	384	263	581	4e-11	75.9
rs:WP_021707641	DNA topoisomerase I [Vibrio alginolyticus].	26.56	320	188	11	77	385	291	574	4e-11	75.9
rs:WP_035829502	DNA topoisomerase I [Cyanobium sp. CACIAM 14].	25.52	337	221	7	37	370	246	555	4e-11	75.9
rs:WP_027970847	DNA topoisomerase III [Streptococcus castoreus].	24.63	337	208	13	59	385	259	559	4e-11	75.5
rs:XP_008887269	DNA topoisomerase III beta-1, putative [Hammondia hammondi].	22.88	354	236	8	39	386	260	582	4e-11	75.9
rs:WP_048260152	DNA topoisomerase I [Pectobacterium carotovorum].	25.53	376	237	12	77	446	285	623	4e-11	75.9
rs:WP_016856973	topoisomerase I [Candidatus Hamiltonella defensa].	25.20	381	232	16	77	446	286	624	4e-11	75.9
rs:WP_039480851	DNA topoisomerase I [Pectobacterium carotovorum].	24.81	399	244	13	61	446	268	623	4e-11	75.9
rs:WP_020478602	hypothetical protein [Myxococcus xanthus].	22.47	454	268	14	41	452	671	1082	4e-11	75.9
rs:WP_024478965	DNA topoisomerase I [Cellulophaga baltica].	25.68	292	181	7	47	334	219	478	4e-11	75.9
tr:A0A0E8V0F1_MYCTX	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CRG19818.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRG19818.1};	25.33	383	231	11	41	399	332	683	4e-11	75.9
rs:WP_018966009	DNA topoisomerase I [Porphyromonas gulae].	27.82	266	155	8	77	338	248	480	4e-11	75.5
tr:V7PWA5_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.35	471	295	15	2	449	173	600	4e-11	75.5
rs:WP_000681437	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	4e-11	75.5
rs:WP_043045652	DNA topoisomerase I [Vibrio parahaemolyticus].	24.34	378	238	13	77	446	291	628	4e-11	75.9
rs:WP_021167566	DNA topoisomerase 1 [Sporomusa ovata].	23.04	434	275	13	47	457	226	623	4e-11	75.5
rs:WP_043039794	DNA topoisomerase I [Vibrio parahaemolyticus].	26.56	320	188	11	77	385	291	574	4e-11	75.9
tr:Q1D812_MYXXD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.12	452	272	13	41	452	679	1090	4e-11	75.9
rs:WP_042681694	DNA topoisomerase I [Anaerosalibacter sp. ND1].	22.25	436	254	12	65	449	246	647	4e-11	75.5
rs:WP_044269192	DNA topoisomerase I [Candidatus Bacteroides timonensis].	26.14	329	211	9	61	385	262	562	4e-11	75.5
tr:A0A0C1D8C7_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.77	331	203	9	41	356	253	552	4e-11	75.9
rs:WP_005390711	MULTISPECIES: topoisomerase I [Vibrio].	26.56	320	188	11	77	385	291	574	4e-11	75.9
rs:WP_027463868	hypothetical protein [Deinococcus ficus].	26.95	308	190	8	42	347	246	520	4e-11	75.5
tr:K4RK22_HELHE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.19	427	266	13	41	450	245	626	4e-11	75.5
rs:WP_006742126	topoisomerase I [Vibrio antiquarius].	26.56	320	188	11	77	385	291	574	4e-11	75.9
tr:Q14PN0_SPICI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.88	410	242	14	60	450	232	594	4e-11	75.5
rs:WP_024640560	DNA topoisomerase I [Pseudomonas syringae].	24.87	398	248	11	71	459	254	609	4e-11	75.5
rs:WP_003146872	DNA topoisomerase I [Gemella haemolysans].	22.59	425	265	11	47	452	225	604	4e-11	75.5
tr:D8LDU2_ECTSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.45	344	177	11	70	356	383	707	4e-11	75.9
rs:WP_039667896	DNA topoisomerase I [Campylobacter lari].	24.94	393	229	16	77	450	255	600	4e-11	75.5
rs:WP_043678229	DNA topoisomerase I [Nocardia vulneris].	24.77	331	203	9	41	356	271	570	4e-11	75.9
rs:WP_003663911	topoisomerase I [Moraxella catarrhalis].	25.63	359	213	17	40	384	263	581	4e-11	75.9
rs:WP_029789004	DNA topoisomerase I [Vibrio harveyi].	25.26	380	232	13	77	446	291	628	4e-11	75.9
tr:A8V019_9AQUI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.15	323	195	9	77	385	252	538	4e-11	75.5
tr:X0TK41_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_L08620 {ECO:0000313|EMBL:GAF93619.1}; Flags: Fragment;	25.00	300	180	10	166	454	13	278	4e-11	73.6
rs:WP_029296505	DNA topoisomerase I [Chryseobacterium hispalense].	27.08	336	192	12	11	334	182	476	4e-11	75.5
rs:WP_025837075	DNA topoisomerase I [Prevotella scopos].	24.48	290	171	8	77	350	252	509	4e-11	75.5
rs:XP_011696596	PREDICTED: DNA topoisomerase 3-beta-1 [Wasmannia auropunctata].	23.79	391	240	14	12	385	231	580	4e-11	75.5
rs:WP_026240474	DNA topoisomerase I [Frankia sp. BCU110501].	24.61	382	238	12	41	404	339	688	4e-11	75.9
tr:A0A077WEE4_9FUNG	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CDS05820.1};	24.51	355	211	10	39	378	279	591	4e-11	75.5
rs:WP_044121391	DNA topoisomerase I, partial [Anaerobiospirillum succiniciproducens].	24.92	333	199	10	32	354	235	526	4e-11	75.5
rs:WP_041436909	DNA topoisomerase I [Thermomicrobium roseum].	24.89	446	217	16	66	457	244	625	4e-11	75.5
rs:WP_029006159	DNA topoisomerase I [Azorhizobium doebereinerae].	26.19	420	241	15	69	454	253	637	4e-11	75.5
tr:A0A090TAB4_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.68	393	231	14	71	446	276	620	4e-11	75.5
rs:WP_042870498	DNA topoisomerase I [Dickeya sp. NCPPB 569].	24.70	421	258	16	40	446	249	624	4e-11	75.5
tr:A0A0A8H6T1_CAMLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.94	393	229	16	77	450	254	599	4e-11	75.5
rs:XP_006581778	PREDICTED: DNA topoisomerase 3-alpha isoform X4 [Glycine max].	22.99	435	259	15	39	451	261	641	4e-11	75.5
tr:G4URA7_NEUT9	SubName: Full=Prokaryotic type I DNA topoisomerase {ECO:0000313|EMBL:EGZ71954.1};	24.68	308	187	8	37	336	247	517	4e-11	75.5
rs:WP_007546838	DNA topoisomerase I [Sulfurihydrogenibium yellowstonense].	26.97	267	153	8	77	335	257	489	4e-11	75.5
rs:WP_045876658	DNA topoisomerase I [Frankia sp. DC12].	26.52	328	185	12	40	354	326	610	4e-11	75.9
rs:WP_014945663	DNA topoisomerase I [Chlamydia psittaci].	24.49	396	248	17	69	449	263	622	4e-11	75.5
rs:WP_001928282	DNA topoisomerase I [Helicobacter pylori].	25.32	395	231	17	74	450	251	599	4e-11	75.5
rs:WP_014224989	DNA topoisomerase I [Tannerella forsythia].	25.87	344	216	11	65	384	241	569	4e-11	75.5
tr:I9XBE8_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	24.42	385	223	15	86	450	9	345	4e-11	75.1
rs:WP_000681489	DNA topoisomerase I [Helicobacter pylori].	24.81	395	233	16	74	450	251	599	4e-11	75.5
tr:K0ELN9_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.77	331	203	9	41	356	253	552	4e-11	75.5
rs:WP_019820987	topoisomerase I [Vibrio splendidus].	26.37	383	224	15	77	446	290	627	4e-11	75.5
rs:WP_023408495	hypothetical protein [uncultured Desulfofustis sp. PB-SRB1].	35.20	125	76	2	257	377	14	137	4e-11	73.6
rs:WP_005858550	DNA topoisomerase III [Parabacteroides distasonis].	26.14	329	211	9	61	385	262	562	4e-11	75.1
rs:WP_036159917	DNA topoisomerase I [Marinomonas ushuaiensis].	23.12	359	232	9	36	384	253	577	4e-11	75.5
rs:WP_006343649	DNA topoisomerase I [Chlamydia psittaci].	24.49	396	248	17	69	449	263	622	4e-11	75.5
rs:WP_016981692	DNA topoisomerase I [Chlamydia psittaci].	24.49	396	248	17	69	449	263	622	4e-11	75.5
rs:XP_008367818	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha-like [Malus domestica].	26.44	261	173	6	39	294	266	512	4e-11	75.1
rs:WP_014946333	DNA topoisomerase I [Chlamydia psittaci].	24.49	396	248	17	69	449	263	622	4e-11	75.5
rs:WP_042902897	DNA topoisomerase [Streptococcus oralis].	23.16	354	224	12	44	385	245	562	4e-11	75.1
rs:WP_017648563	DNA topoisomerase III [Streptococcus agalactiae].	23.16	354	224	12	44	385	245	562	4e-11	75.1
rs:XP_006692995	DNA topoisomerase-like protein [Chaetomium thermophilum var. thermophilum DSM 1495].	25.36	280	165	8	61	333	280	522	4e-11	75.5
rs:WP_000237215	DNA topoisomerase III [Streptococcus agalactiae].	22.31	381	245	13	17	385	221	562	4e-11	75.1
tr:A0A0D4C3V8_9MICC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.62	363	223	13	42	384	246	581	4e-11	75.5
rs:WP_003125271	topoisomerase I - like protein, partial [Pseudomonas aeruginosa].	25.62	281	160	9	199	459	5	256	4e-11	72.8
rs:XP_009850867	hypothetical protein NEUTE1DRAFT_81659 [Neurospora tetrasperma FGSC 2508].	25.09	283	168	7	61	336	280	525	4e-11	75.5
rs:WP_020178307	hypothetical protein [Methylopila sp. M107].	24.56	456	266	17	39	454	221	638	4e-11	75.5
rs:WP_021997276	DNA topoisomerase [Ruminococcus sp. CAG:724].	22.60	438	275	14	36	452	213	607	4e-11	75.5
rs:WP_025383880	DNA topoisomerase I [Yersinia similis].	23.95	380	238	13	77	446	290	628	4e-11	75.5
rs:WP_030668102	DNA topoisomerase I [Streptomyces cellulosae].	26.28	293	167	11	77	354	299	557	4e-11	75.5
tr:A0A067JZR5_JATCU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.60	374	228	13	39	396	263	598	4e-11	75.1
rs:WP_038885822	DNA topoisomerase I [Vibrio rotiferianus].	24.87	386	226	13	77	446	291	628	4e-11	75.5
rs:WP_027500390	DNA topoisomerase I [Rhodococcus sp. UNC363MFTsu5.1].	25.23	329	200	9	41	354	269	566	4e-11	75.5
rs:WP_012017586	topoisomerase I [Enterobacter sp. 638].	25.53	380	232	14	77	446	284	622	4e-11	75.5
rs:WP_005466649	DNA topoisomerase I [Saccharomonospora glauca].	26.30	365	220	12	40	384	271	606	5e-11	75.5
rs:WP_027449291	DNA topoisomerase I [Prevotella brevis].	25.00	296	186	8	47	335	222	488	5e-11	75.5
rs:WP_023093855	hypothetical protein, partial [Pseudomonas aeruginosa].	25.42	299	169	10	186	459	13	282	5e-11	73.2
tr:S7K4H3_CHLPS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.49	396	248	17	69	449	247	606	5e-11	75.5
rs:WP_016966554	DNA topoisomerase I [Chlamydia psittaci].	24.49	396	248	17	69	449	263	622	5e-11	75.5
tr:A0A090RC47_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	36.89	103	65	0	35	137	145	247	5e-11	72.8
rs:WP_008911059	DNA topoisomerase I subunit omega [Providencia burhodogranariea].	25.55	321	193	11	77	386	283	568	5e-11	75.5
rs:WP_039126264	DNA topoisomerase I [Gilliamella apicola].	24.59	431	258	16	43	452	249	633	5e-11	75.5
rs:WP_013597664	DNA topoisomerase I [Weeksella virosa].	24.46	323	209	8	47	367	219	508	5e-11	75.5
rs:WP_017043915	topoisomerase I [Vibrio ordalii].	24.37	398	235	14	69	446	277	628	5e-11	75.5
rs:WP_024948064	DNA topoisomerase I [Helicobacter pylori].	24.56	395	234	16	74	450	251	599	5e-11	75.5
rs:WP_037620536	hypothetical protein, partial [Streptococcus parauberis].	40.40	99	52	2	230	328	2	93	5e-11	70.1
rs:WP_010437771	MULTISPECIES: topoisomerase I [Vibrio].	26.37	383	224	15	77	446	290	627	5e-11	75.5
rs:WP_006849198	DNA topoisomerase I [Prevotella copri].	25.09	267	161	8	77	338	252	484	5e-11	75.5
rs:WP_013609494	DNA topoisomerase I [Mycoplasma suis].	25.13	398	238	13	74	450	269	627	5e-11	75.5
rs:WP_030573656	DNA topoisomerase I [Streptomyces sclerotialus].	25.94	293	168	11	77	354	299	557	5e-11	75.5
rs:XP_011389249	hypothetical protein UMAG_11929 [Ustilago maydis 521].	25.38	331	191	12	41	357	274	562	5e-11	75.5
rs:WP_017044653	topoisomerase I [Vibrio ordalii].	24.37	398	235	14	69	446	277	628	5e-11	75.5
rs:XP_001418273	predicted protein [Ostreococcus lucimarinus CCE9901].	23.55	361	222	11	40	385	279	600	5e-11	75.5
tr:M5D4S5_STEMA	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CCP18548.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CCP18548.1};	30.12	249	137	10	110	350	1	220	5e-11	75.1
rs:WP_012037613	DNA topoisomerase I [Clavibacter michiganensis].	28.17	323	180	14	77	379	288	578	5e-11	75.5
tr:S7K796_CHLPS	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	24.49	396	248	17	69	449	216	575	5e-11	75.5
rs:WP_020285757	DNA topoisomerase I [Osedax symbiont Rs2].	25.38	394	226	17	77	452	295	638	5e-11	75.5
rs:WP_025315708	DNA topoisomerase I [Gilliamella apicola].	24.59	431	258	16	43	452	249	633	5e-11	75.5
tr:D6BE65_FUSNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	23.43	397	243	14	60	431	270	630	5e-11	75.5
tr:E4Y9S6_OIKDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.07	435	271	15	39	453	256	642	5e-11	75.5
rs:WP_043584467	DNA topoisomerase I [Clavibacter michiganensis].	28.17	323	180	14	77	379	288	578	5e-11	75.5
rs:XP_001388262	DNA topoisomerase III [Cryptosporidium parvum Iowa II].	23.85	327	201	9	39	354	309	598	5e-11	75.5
rs:WP_036907504	DNA topoisomerase I [Prevotella salivae].	25.29	261	162	6	77	334	252	482	5e-11	75.5
rs:WP_017020611	topoisomerase I [Aliivibrio logei].	24.49	396	232	14	77	452	290	638	5e-11	75.5
rs:WP_007560043	DNA topoisomerase I [Bacteroides plebeius].	27.04	270	156	7	77	340	249	483	5e-11	75.5
rs:WP_029480505	DNA topoisomerase I [Deinococcus marmoris].	25.08	323	194	10	40	344	250	542	5e-11	75.5
rs:WP_034233047	DNA topoisomerase I [Arcanobacterium sp. S3PF19].	27.19	342	192	13	40	358	249	556	5e-11	75.5
rs:WP_036861839	DNA topoisomerase I [Prevotella melaninogenica].	25.56	266	160	7	77	334	252	487	5e-11	75.5
rs:WP_029552434	DNA topoisomerase I [Thermocrinis sp. GBS].	25.55	317	176	12	74	377	239	508	5e-11	75.1
rs:WP_042858844	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	25.00	268	152	8	212	459	7	245	5e-11	72.8
rs:WP_040686122	DNA topoisomerase I [Nocardia vinacea].	25.39	323	185	10	47	354	285	566	5e-11	75.5
rs:WP_038889185	DNA topoisomerase I [Vibrio campbellii].	24.87	386	226	13	77	446	291	628	5e-11	75.5
rs:WP_012725699	DNA topoisomerase I [Beutenbergia cavernae].	25.38	390	231	11	30	387	243	604	5e-11	75.5
rs:WP_014946975	DNA topoisomerase I [Chlamydia psittaci].	24.49	396	248	17	69	449	263	622	5e-11	75.5
tr:K2D5V3_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.11	442	247	19	47	454	227	618	5e-11	75.5
rs:WP_021304414	DNA topoisomerase I [Helicobacter pylori].	25.57	395	230	17	74	450	251	599	5e-11	75.5
rs:WP_045109699	DNA topoisomerase I [Moritella viscosa].	25.38	394	233	16	77	452	294	644	5e-11	75.5
tr:U2KJL7_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.29	261	162	6	77	334	254	484	5e-11	75.5
rs:WP_015871044	topoisomerase I [Edwardsiella ictaluri].	24.38	320	198	9	77	386	284	569	5e-11	75.5
rs:WP_033617937	DNA topoisomerase I [Helicobacter pylori].	24.75	396	232	17	74	450	251	599	5e-11	75.5
rs:WP_033781617	DNA topoisomerase I [Helicobacter pylori].	23.99	396	235	16	74	450	251	599	5e-11	75.5
rs:WP_014518576	DNA topoisomerase I [Chlamydia psittaci].	24.49	396	248	17	69	449	256	615	5e-11	75.5
rs:WP_005426314	topoisomerase I [Vibrio campbellii].	24.87	386	226	13	77	446	291	628	5e-11	75.5
rs:WP_047690891	DNA topoisomerase I [Vibrio sp. ZOR0018].	24.37	398	235	14	69	446	277	628	5e-11	75.5
rs:WP_008565877	DNA topoisomerase I [Prevotella maculosa].	26.32	266	153	8	77	334	252	482	5e-11	75.5
rs:WP_033896482	DNA topoisomerase I [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	271	622	5e-11	75.5
rs:WP_006821526	DNA topoisomerase I [Corynebacterium casei].	26.43	314	180	13	51	354	278	550	5e-11	75.5
rs:WP_025386990	DNA topoisomerase I [Corynebacterium casei].	26.43	314	180	13	51	354	278	550	5e-11	75.5
tr:K1T5M9_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EKC64968.1}; Flags: Fragment;	27.66	282	156	12	110	379	21	266	5e-11	73.6
rs:WP_046493073	DNA topoisomerase I [Candidatus Hamiltonella defensa].	24.74	380	235	14	77	446	286	624	5e-11	75.5
rs:WP_003670294	topoisomerase I [Moraxella catarrhalis].	25.63	359	213	17	40	384	263	581	5e-11	75.5
rs:WP_013857079	topoisomerase I [Vibrio anguillarum].	24.37	398	235	14	69	446	277	628	5e-11	75.5
rs:WP_045075623	DNA topoisomerase I [Arthrobacter sp. IHBB 11108].	25.62	363	223	13	42	384	270	605	5e-11	75.5
rs:WP_045071992	DNA topoisomerase I [Chlamydophila abortus].	24.23	421	266	17	45	449	239	622	5e-11	75.5
tr:E4X5F4_OIKDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.61	435	273	15	39	453	256	642	5e-11	75.5
rs:WP_017047729	topoisomerase I [Vibrio ordalii].	24.37	398	235	14	69	446	277	628	5e-11	75.5
rs:XP_011107696	hypothetical protein H072_1705 [Dactylellina haptotyla CBS 200.50].	24.59	305	185	7	40	334	203	472	5e-11	75.1
rs:WP_031656896	DNA topoisomerase I [Mycobacterium tuberculosis].	25.33	383	231	11	41	399	271	622	5e-11	75.5
tr:F1L3P3_ASCSU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.74	303	183	10	93	388	2	269	5e-11	74.7
rs:WP_010447216	topoisomerase I [Vibrio rotiferianus].	25.46	326	186	10	77	386	291	575	5e-11	75.5
rs:WP_045417635	DNA topoisomerase I [Vibrio campbellii].	24.87	386	226	13	77	446	291	628	5e-11	75.5
rs:WP_022941114	topoisomerase I [Psychromonas hadalis].	27.15	383	223	15	77	446	292	631	5e-11	75.5
rs:WP_013865799	DNA topoisomerase I [Microlunatus phosphovorus].	23.61	360	231	10	42	386	260	590	5e-11	75.5
rs:WP_031459792	DNA topoisomerase I [Chloroflexus sp. MS-G].	27.32	355	208	11	47	378	231	558	5e-11	75.1
rs:WP_011097448	DNA topoisomerase I [Chlamydophila abortus].	24.23	421	266	17	45	449	239	622	5e-11	75.5
rs:WP_038557105	DNA topoisomerase I [Draconibacterium orientale].	27.44	266	157	8	73	335	251	483	5e-11	75.1
rs:WP_006151577	DNA topoisomerase [Streptococcus infantis].	25.34	296	184	10	44	334	245	508	5e-11	74.7
rs:XP_007792536	putative dna topoisomerase iii protein [Eutypa lata UCREL1].	24.09	328	201	10	18	334	129	419	5e-11	75.1
rs:WP_029029760	DNA topoisomerase I [Salinarimonas rosea].	25.17	453	260	15	34	452	227	634	5e-11	75.5
rs:WP_038559666	DNA topoisomerase I [Neorickettsia helminthoeca].	24.05	420	257	15	65	455	248	634	5e-11	75.1
rs:WP_038010604	DNA topoisomerase I [Tannerella sp. oral taxon BU063].	27.42	310	177	11	40	338	213	485	5e-11	75.1
rs:WP_033757842	DNA topoisomerase I [Pantoea agglomerans].	25.16	322	193	9	77	386	293	578	5e-11	75.5
rs:WP_013661399	topoisomerase I [Marinomonas mediterranea].	22.52	404	268	11	35	431	252	617	5e-11	75.5
rs:XP_007003116	hypothetical protein TREMEDRAFT_73248 [Tremella mesenterica DSM 1558].	25.34	296	170	9	73	357	300	555	5e-11	75.5
rs:WP_000772479	DNA topoisomerase I [Acinetobacter baumannii].	26.86	350	200	15	19	356	195	500	5e-11	74.7
rs:WP_014296545	DNA topoisomerase I [Marinitoga piezophila].	23.85	390	230	12	60	428	238	581	5e-11	75.1
rs:WP_016800735	topoisomerase I [Vibrio cyclitrophicus].	26.37	383	224	15	77	446	290	627	5e-11	75.5
rs:WP_012549908	topoisomerase I [Aliivibrio salmonicida].	24.49	396	232	14	77	452	290	638	5e-11	75.5
rs:WP_025613743	DNA topoisomerase I [Cellulophaga baltica].	26.26	278	169	7	61	334	233	478	5e-11	75.1
rs:WP_017049879	topoisomerase I [Vibrio ordalii].	24.37	398	235	14	69	446	277	628	5e-11	75.1
rs:XP_012061314	PREDICTED: DNA topoisomerase 3-beta-1 [Atta cephalotes].	24.38	361	217	13	40	385	267	586	5e-11	75.1
rs:WP_022802495	DNA topoisomerase I [Deinococcus sp. 2009].	27.27	308	189	10	42	347	246	520	5e-11	75.1
rs:WP_013882357	DNA topoisomerase I [[Cellvibrio] gilvus].	25.93	378	231	11	31	387	241	590	5e-11	75.5
rs:WP_026742481	DNA topoisomerase I [Lonsdalea quercina].	25.26	380	233	13	77	446	284	622	6e-11	75.1
rs:WP_021965327	DNA topoisomerase [Prevotella sp. CAG:1185].	24.62	325	206	9	14	334	192	481	6e-11	75.1
rs:WP_040092879	DNA topoisomerase I [Spiroplasma poulsonii].	24.03	412	249	12	60	453	232	597	6e-11	75.1
rs:WP_033787708	DNA topoisomerase I [Pantoea agglomerans].	25.16	322	193	9	77	386	293	578	6e-11	75.1
rs:WP_031591590	DNA topoisomerase I [Pantoea agglomerans].	25.16	322	193	9	77	386	293	578	6e-11	75.1
rs:WP_013931564	DNA topoisomerase I [Pseudothermotoga thermarum].	24.54	379	224	11	70	434	241	571	6e-11	75.1
rs:WP_032496840	DNA topoisomerase I, partial [Hydrogenivirga sp. 128-5-R1-1].	24.15	323	195	9	77	385	252	538	6e-11	74.7
rs:WP_018346637	topoisomerase I [Gallibacterium anatis].	25.07	375	240	12	77	446	290	628	6e-11	75.1
tr:I2WFK0_ECOLX	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EII23428.1};	32.04	103	70	0	31	133	237	339	6e-11	73.9
rs:WP_010244475	MULTISPECIES: topoisomerase I [Pantoea].	25.16	322	193	9	77	386	293	578	6e-11	75.1
rs:WP_013870165	DNA topoisomerase I [Lacinutrix sp. 5H-3-7-4].	27.20	261	155	7	77	334	249	477	6e-11	75.1
rs:WP_022436798	DNA topoisomerase [Prevotella sp. CAG:279].	23.57	314	200	8	26	334	238	516	6e-11	75.1
rs:WP_032576958	DNA topoisomerase I, partial [Bacteroides fragilis].	24.47	282	195	8	21	294	56	327	6e-11	73.6
gp:MYCRRN1_17	DNA topoisomerase I [Mycoplasma gallisepticum]	23.60	445	271	16	30	450	248	647	6e-11	75.1
rs:WP_004354064	DNA topoisomerase I [Prevotella denticola].	25.34	292	166	9	77	350	252	509	6e-11	75.1
rs:WP_033619145	DNA topoisomerase I [Helicobacter pylori].	23.99	396	235	16	74	450	251	599	6e-11	75.1
tr:Q08Q69_STIAD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.68	385	216	12	41	385	284	634	6e-11	75.1
rs:WP_033614663	DNA topoisomerase I [Helicobacter pylori].	24.75	396	232	17	74	450	251	599	6e-11	75.1
rs:WP_029955435	DNA topoisomerase I [Atribacteria bacterium SCGC AAA255-N14].	22.79	430	270	11	47	456	227	614	6e-11	75.1
tr:G0MZ90_CAEBE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.57	471	290	18	12	457	777	1202	6e-11	75.5
rs:WP_029455134	DNA topoisomerase I [Candidatus Pelagibacter ubique].	24.94	433	262	16	51	454	234	632	6e-11	75.1
rs:WP_000681443	DNA topoisomerase I [Helicobacter pylori].	24.56	395	234	16	74	450	251	599	6e-11	75.1
rs:WP_039455829	DNA topoisomerase I [endosymbiont of Acanthamoeba sp. UWC36].	23.60	445	258	14	43	449	227	627	6e-11	75.1
rs:WP_000557251	DNA topoisomerase III [Streptococcus agalactiae].	24.53	318	202	12	74	385	274	559	6e-11	74.7
rs:WP_015144218	DNA topoisomerase I [Pleurocapsa minor].	25.87	317	202	6	77	387	285	574	6e-11	75.1
rs:WP_004288696	DNA topoisomerase III [Bacteroides eggerthii].	25.84	329	212	9	61	385	262	562	6e-11	74.7
rs:WP_034508749	DNA topoisomerase I [Actinomyces sp. S4-C9].	27.46	335	186	12	45	354	256	558	6e-11	75.1
rs:WP_021849581	DNA topoisomerase [Firmicutes bacterium CAG:791].	23.99	446	256	16	47	454	228	628	6e-11	75.1
rs:WP_029812658	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	37.50	96	60	0	309	404	1	96	6e-11	70.5
rs:WP_027130929	DNA topoisomerase I [Gemella cuniculi].	22.70	423	268	12	47	452	225	605	6e-11	75.1
tr:F9PXW2_9STRE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	24.76	307	186	10	44	341	245	515	6e-11	74.7
rs:WP_022907329	DNA topoisomerase I, partial [Curtobacterium sp. B18].	24.71	348	213	11	30	354	121	442	6e-11	75.1
tr:A0A0C3QJC6_9HOMO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.86	379	213	14	28	378	245	583	6e-11	74.7
rs:WP_027121510	DNA topoisomerase I [Mycoplasma leonicaptivi].	24.68	385	209	16	92	452	269	596	6e-11	74.7
rs:WP_020378945	hypothetical protein [Candidatus Microthrix parvicella].	26.01	323	187	11	77	378	291	582	6e-11	75.1
rs:WP_033771067	DNA topoisomerase I [Helicobacter pylori].	23.99	396	235	16	74	450	251	599	6e-11	75.1
rs:WP_033911113	conjugal transfer protein TraE, partial [Neisseria gonorrhoeae].	27.67	159	70	1	346	459	1	159	6e-11	71.2
tr:A0A0F6CLB7_MYCGL	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:AHB99889.1};	23.87	444	271	18	30	450	248	647	6e-11	75.1
rs:WP_030561185	DNA topoisomerase I [Streptomyces aureocirculatus].	25.60	293	169	11	77	354	299	557	6e-11	75.1
rs:XP_002144156	DNA topoisomerase III, putative [Talaromyces marneffei ATCC 18224].	25.57	305	184	9	40	337	261	529	6e-11	74.7
rs:WP_029906193	DNA topoisomerase I [Prevotella sp. 10(H)].	26.34	262	157	6	77	334	252	481	6e-11	75.1
rs:WP_019207142	hypothetical protein [Phocaeicola abscessus].	26.22	267	157	8	77	338	253	484	6e-11	75.1
rs:WP_020255499	hypothetical protein [Parcubacteria bacterium SCGC AAA010-E09].	26.21	393	235	16	67	449	237	584	6e-11	75.1
tr:W4W354_ATTCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.04	460	266	17	30	449	242	653	6e-11	75.1
tr:T2SB35_HELPX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.99	396	235	16	74	450	251	599	6e-11	75.1
rs:WP_018029297	hypothetical protein [Porphyromonas somerae].	26.62	263	159	7	77	337	249	479	6e-11	75.1
rs:WP_021776257	glutamyl-tRNA amidotransferase subunit A Glu-ADT subunit A protein [alpha proteobacterium RS24].	23.71	447	269	13	44	454	225	635	6e-11	75.1
sp:TOP1_MYCGA	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	23.60	445	271	16	30	450	248	647	6e-11	75.1
rs:WP_013103076	MULTISPECIES: DNA topoisomerase I [Leuconostoc].	25.18	413	231	19	66	452	268	628	6e-11	75.1
rs:WP_038622494	DNA topoisomerase I [Dyella jiangningensis].	27.22	338	193	14	66	380	254	561	6e-11	75.1
rs:WP_028897255	DNA topoisomerase I [Prevotella sp. HUN102].	25.63	277	160	8	71	334	245	488	6e-11	75.1
rs:WP_012225025	DNA topoisomerase 1 [Candidatus Microthrix parvicella].	26.01	323	187	11	77	378	291	582	6e-11	75.1
rs:WP_027390823	DNA topoisomerase I [Chrysiogenes arsenatis].	25.06	427	260	17	47	452	226	613	7e-11	75.1
rs:WP_007641057	topoisomerase I [Cellvibrio sp. BR].	25.96	416	252	16	51	452	269	642	7e-11	75.1
rs:XP_009026009	hypothetical protein HELRODRAFT_114559 [Helobdella robusta].	24.03	437	264	14	40	450	251	645	7e-11	75.1
rs:WP_012592797	DNA topoisomerase I [Methylocella silvestris].	25.93	432	239	15	61	452	244	634	7e-11	75.1
rs:XP_010444313	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha-like [Camelina sativa].	22.74	475	281	15	18	451	243	672	7e-11	75.1
rs:WP_026303996	DNA topoisomerase I [Kaistia granuli].	25.78	419	237	18	71	452	253	634	7e-11	75.1
rs:WP_012765531	MULTISPECIES: topoisomerase I [Dickeya].	24.87	382	232	12	77	446	287	625	7e-11	75.1
tr:G8PNI3_PSEUV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.06	419	249	14	60	446	238	623	7e-11	75.1
rs:WP_044010110	DNA topoisomerase I [Lactobacillus sp. WDC04].	23.59	407	246	16	65	452	265	625	7e-11	74.7
rs:WP_012963136	DNA topoisomerase I [Hydrogenobacter thermophilus].	24.85	342	201	11	47	377	216	512	7e-11	74.3
rs:WP_010320022	topoisomerase I [Vibrio ordalii].	25.37	339	190	11	69	385	277	574	7e-11	75.1
tr:B0RAE2_CLAMS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.17	323	180	14	77	379	330	620	7e-11	75.1
rs:WP_045722958	DNA topoisomerase I, partial [Salmonella enterica].	27.00	263	161	7	187	446	22	256	7e-11	74.3
rs:WP_010249084	DNA topoisomerase I [Acetivibrio cellulolyticus].	23.56	399	248	14	77	457	256	615	7e-11	74.7
tr:G4B182_AGGAC	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGY49791.1};	46.75	77	41	0	309	385	1	77	7e-11	70.5
rs:WP_028989890	DNA topoisomerase I [Thermithiobacillus tepidarius].	25.59	469	258	19	32	456	203	624	7e-11	75.1
rs:WP_002557752	DNA topoisomerase I [Mycoplasma flocculare].	24.01	479	263	20	19	459	205	620	7e-11	74.7
rs:WP_041885017	DNA topoisomerase I [Pedobacter sp. NL19].	26.57	350	220	11	61	386	234	570	7e-11	75.1
rs:WP_029842021	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	37.50	96	60	0	309	404	1	96	7e-11	70.5
rs:WP_017025175	topoisomerase I [Vibrio rumoiensis].	26.10	341	189	11	68	386	275	574	7e-11	75.1
tr:Q1H4T9_METFK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.44	418	260	12	51	449	237	613	7e-11	74.7
rs:WP_000295979	hypothetical protein, partial [Escherichia coli].	27.35	245	147	7	206	447	3	219	7e-11	71.6
rs:WP_047119826	DNA topoisomerase I [Arthrobacter sp. YC-RL1].	25.23	329	204	10	42	356	259	559	7e-11	75.1
rs:WP_009641356	DNA topoisomerase I [Capnocytophaga sp. CM59].	25.48	314	185	9	35	334	198	476	7e-11	74.7
rs:WP_047377410	DNA topoisomerase I [Chryseobacterium sp. YR459].	26.01	323	191	11	36	351	217	498	7e-11	74.7
rs:WP_041768668	DNA topoisomerase I [Pseudovibrio sp. FO-BEG1].	25.06	419	249	14	60	446	243	628	7e-11	75.1
rs:WP_027304177	DNA topoisomerase I [Campylobacter upsaliensis].	25.06	399	227	18	74	450	252	600	7e-11	74.7
rs:WP_015231277	DNA topoisomerase I [Deinococcus peraridilitoris].	25.50	400	237	12	35	421	240	591	7e-11	74.7
rs:WP_002762881	DNA topoisomerase I [Leptospira borgpetersenii].	22.22	441	268	15	39	450	210	604	7e-11	74.7
rs:WP_010785769	DNA topoisomerase I subunit omega [Haemophilus parasuis].	26.15	283	172	8	77	356	292	540	7e-11	74.7
rs:WP_039794607	DNA topoisomerase I [Nocardia araoensis].	25.85	325	185	10	47	356	287	570	7e-11	75.1
rs:WP_017950657	MULTISPECIES: hypothetical protein [Marinimicrobia].	24.81	391	231	13	86	452	264	615	7e-11	74.7
rs:WP_036933542	DNA topoisomerase I, partial [Propionibacteriaceae bacterium P6A17].	25.72	346	208	10	51	386	273	579	7e-11	74.7
rs:WP_033115350	DNA topoisomerase I [Aeromonas lacus].	24.52	420	259	15	49	452	259	636	7e-11	74.7
rs:XP_011632249	PREDICTED: DNA topoisomerase 3-beta-1, partial [Pogonomyrmex barbatus].	23.40	359	222	12	12	357	232	550	7e-11	74.3
rs:WP_009186409	DNA topoisomerase I [Cecembia lonarensis].	26.69	266	155	9	77	335	248	480	8e-11	74.7
rs:WP_019539088	hypothetical protein [Proteiniphilum acetatigenes].	27.24	323	189	10	40	351	215	502	8e-11	74.7
rs:WP_005710869	topoisomerase I [[Haemophilus] parasuis].	26.15	283	172	8	77	356	292	540	8e-11	74.7
rs:WP_035176689	DNA topoisomerase [Acidobacteria bacterium KBS 146].	23.08	468	272	19	34	450	227	657	8e-11	74.7
rs:WP_008440553	DNA topoisomerase I, archaeal [Thaumarchaeota archaeon SCGC AB-539-E09].	27.97	261	160	10	38	291	248	487	8e-11	74.3
rs:WP_012621609	topoisomerase I [[Haemophilus] parasuis].	26.15	283	172	8	77	356	292	540	8e-11	74.7
rs:WP_034953704	DNA topoisomerase I [Erythrobacter sp. JL475].	24.23	388	229	12	1	371	171	510	8e-11	74.7
rs:WP_012912458	DNA topoisomerase I [Pirellula staleyi].	28.01	282	165	9	77	350	293	544	8e-11	74.7
rs:WP_035925040	DNA topoisomerase I [Kocuria polaris].	25.41	366	221	14	42	384	265	601	8e-11	74.7
rs:WP_038139440	hypothetical protein, partial [Thiomicrospira sp. Milos-T1].	25.77	291	171	10	69	354	242	492	8e-11	74.3
rs:WP_043452439	DNA topoisomerase I [Arthrobacter phenanthrenivorans].	27.43	288	173	10	77	354	289	550	8e-11	74.7
rs:WP_021116753	DNA topoisomerase I [Haemophilus parasuis].	26.15	283	172	8	77	356	292	540	8e-11	74.7
rs:WP_017816939	DNA topoisomerase I [Acinetobacter baumannii].	26.78	351	199	16	19	356	195	500	8e-11	74.3
rs:WP_035073895	DNA topoisomerase I [Anditalea andensis].	24.25	301	188	6	36	334	217	479	8e-11	74.7
rs:WP_009358544	DNA topoisomerase I [Arthrobacter nitrophenolicus].	26.90	290	172	11	77	354	289	550	8e-11	74.7
rs:WP_010853341	DNA topoisomerase I [Cyclobacteriaceae bacterium AK24].	26.15	260	162	6	77	334	248	479	8e-11	74.7
rs:WP_041748256	DNA topoisomerase I [Bradyrhizobium sp. S23321].	23.64	423	260	12	61	452	244	634	8e-11	74.7
tr:M6VWD0_9LEPT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.80	437	262	17	40	450	211	602	8e-11	74.3
rs:WP_027383415	DNA topoisomerase I [Chryseobacterium caeni].	26.30	327	181	12	36	349	217	496	8e-11	74.7
rs:WP_021109419	DNA topoisomerase I [Haemophilus parasuis].	26.15	283	172	8	77	356	292	540	8e-11	74.7
gp:CP005384_1002	DNA topoisomerase I subunit omega [Haemophilus parasuis ZJ0906]	26.15	283	172	8	77	356	234	482	8e-11	74.7
rs:WP_035495014	DNA topoisomerase I [[Haemophilus] parasuis].	26.15	283	172	8	77	356	292	540	8e-11	74.7
rs:WP_037330521	DNA topoisomerase I [Saccharothrix syringae].	26.05	357	219	11	37	377	265	592	8e-11	74.7
tr:A0A0B4I445_9HYPO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KIE02804.1}; Flags: Fragment;	25.00	276	174	6	65	339	306	549	8e-11	74.7
rs:WP_018520405	MULTISPECIES: DNA topoisomerase I [Streptomyces].	25.60	293	169	11	77	354	301	559	8e-11	74.7
rs:WP_008712829	DNA topoisomerase [Rhodococcus sp. AW25M09].	27.13	328	195	11	41	354	265	562	8e-11	74.7
tr:A0A0D2TRF5_CRYGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.44	287	175	7	73	354	299	551	8e-11	74.7
rs:WP_030954344	DNA topoisomerase I [Streptomyces sp. NRRL F-5140].	25.94	293	168	11	77	354	299	557	8e-11	74.7
rs:WP_035490613	DNA topoisomerase I [Haemophilus parasuis].	26.15	283	172	8	77	356	292	540	8e-11	74.7
rs:WP_014922671	DNA topoisomerase I [Arthrobacter sp. Rue61a].	26.21	290	174	10	77	354	289	550	8e-11	74.7
tr:F8PV61_SERL3	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.79	359	213	12	39	380	256	574	8e-11	74.7
rs:XP_007163790	hypothetical protein PHAVU_001G264300g [Phaseolus vulgaris].	24.46	323	194	11	39	351	254	536	8e-11	74.7
tr:K2NGF1_TRYCR	SubName: Full=DNA topoisomerase III, putative {ECO:0000313|EMBL:EKF38435.1};	23.67	376	241	11	73	434	287	630	8e-11	74.7
rs:WP_006295453	DNA topoisomerase I [Bifidobacterium gallicum].	26.51	347	195	13	35	354	240	553	8e-11	74.7
tr:E7A0Y6_SPORE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.38	331	191	11	41	357	274	562	8e-11	74.7
tr:U0FRZ6_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.23	329	200	10	41	354	247	544	8e-11	74.7
gp:KJ850907_18	TraB [uncultured bacterium]	24.94	401	249	14	70	459	252	611	8e-11	74.7
rs:WP_021110589	DNA topoisomerase I [Haemophilus parasuis].	26.15	283	172	8	77	356	292	540	9e-11	74.7
rs:WP_012145384	MULTISPECIES: topoisomerase I [Serratia].	24.41	381	235	13	77	446	284	622	9e-11	74.7
rs:XP_975504	PREDICTED: DNA topoisomerase 3-beta-1 [Tribolium castaneum].	22.73	352	234	10	40	385	262	581	9e-11	74.7
tr:V4YZV7_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.51	437	274	13	39	453	260	649	9e-11	74.7
rs:XP_003193955	DNA topoisomerase type I [Cryptococcus gattii WM276].	25.44	287	175	7	73	354	299	551	9e-11	74.7
rs:WP_007351952	topoisomerase I [Marinobacter sp. ELB17].	24.81	403	244	15	59	446	276	634	9e-11	74.7
rs:WP_040316801	DNA topoisomerase I [Actinomyces europaeus].	27.46	335	186	12	45	354	256	558	9e-11	74.7
rs:WP_004280500	DNA topoisomerase I [Leptospira borgpetersenii].	22.22	441	268	15	39	450	210	604	9e-11	74.3
rs:WP_016563078	DNA topoisomerase [Bacteroides sp. CAG:927].	26.99	289	164	10	69	346	241	493	9e-11	74.7
rs:XP_002368584	DNA topoisomerase III beta-1, putative [Toxoplasma gondii ME49].	22.82	355	235	9	39	386	243	565	9e-11	74.7
rs:WP_018362460	DNA topoisomerase I [Prevotella nanceiensis].	25.56	266	163	8	77	338	252	486	9e-11	74.7
rs:WP_034328503	MULTISPECIES: DNA topoisomerase I [Helicobacter].	25.91	359	206	16	48	385	228	547	9e-11	74.3
rs:WP_019553209	hypothetical protein [Propionispira raffinosivorans].	25.00	412	243	13	69	457	249	617	9e-11	74.3
rs:WP_010532720	DNA topoisomerase I [Brachybacterium squillarum].	24.86	358	228	9	49	394	261	589	9e-11	74.7
rs:WP_017832494	DNA topoisomerase I [Kocuria sp. UCD-OTCP].	25.41	366	221	14	42	384	265	601	9e-11	74.7
rs:WP_012713672	DNA topoisomerase I [Sulfolobus islandicus].	26.09	368	212	16	73	424	279	602	9e-11	74.3
rs:WP_011006940	DNA topoisomerase I [Chlamydophila caviae].	24.24	396	249	17	69	449	263	622	9e-11	74.7
rs:WP_000237216	DNA topoisomerase III [Streptococcus pneumoniae].	23.16	354	224	12	44	385	245	562	9e-11	74.3
rs:WP_011775956	DNA topoisomerase I [Arthrobacter aurescens].	26.21	290	174	10	77	354	289	550	9e-11	74.7
rs:WP_019746651	MULTISPECIES: DNA topoisomerase I [Rhodococcus].	25.23	329	200	10	41	354	266	563	9e-11	74.7
rs:WP_047889827	DNA topoisomerase I [Rhodococcus sp. ARP2].	25.23	329	200	10	41	354	266	563	9e-11	74.7
rs:WP_022430037	DNA topoisomerase [Prevotella stercorea CAG:629].	26.89	264	161	8	77	338	252	485	9e-11	74.3
rs:WP_010511451	DNA topoisomerase I [SAR324 cluster bacterium SCGC AAA001-C10].	25.00	360	219	11	40	377	213	543	9e-11	74.3
rs:WP_012716149	DNA topoisomerase I [Sulfolobus islandicus].	26.09	368	212	16	73	424	279	602	9e-11	74.3
rs:WP_018748115	DNA topoisomerase I [Chitiniphilus shinanonensis].	23.89	427	270	12	43	452	228	616	9e-11	74.3
tr:I0G6C5_9BRAD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.64	423	260	12	61	452	269	659	9e-11	74.7
rs:WP_045721371	DNA topoisomerase I, partial [Salmonella enterica].	28.30	265	151	10	77	337	284	513	9e-11	73.9
rs:XP_007922203	hypothetical protein MYCFIDRAFT_193524 [Pseudocercospora fijiensis CIRAD86].	26.26	278	158	9	73	340	399	639	9e-11	74.3
rs:WP_026903078	DNA topoisomerase I [Pedobacter glucosidilyticus].	22.73	374	222	8	70	403	243	589	9e-11	74.3
rs:WP_021883971	DNA topoisomerase, partial [Ruminococcus sp. CAG:108].	25.68	331	173	13	166	449	69	373	9e-11	73.6
rs:WP_033952290	DNA topoisomerase I [Streptomyces sp. CNQ431].	24.48	335	204	11	35	354	256	556	9e-11	74.7
rs:WP_018910698	DNA topoisomerase I [Prevotella veroralis].	24.37	316	193	9	30	334	207	487	9e-11	74.3
rs:WP_000681464	DNA topoisomerase I [Helicobacter pylori].	25.57	395	230	17	74	450	251	599	1e-10	74.3
rs:WP_010645814	topoisomerase I [Vibrio campbellii].	24.61	386	227	13	77	446	291	628	1e-10	74.3
rs:WP_025636650	DNA topoisomerase I [Vibrio parahaemolyticus].	24.60	378	237	13	77	446	291	628	1e-10	74.3
rs:WP_029756156	hypothetical protein, partial [Planctomycetes bacterium SCGC AAA282-C19].	24.88	414	240	16	74	459	20	390	1e-10	73.9
rs:WP_023169027	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	28.30	265	151	10	77	337	284	513	1e-10	73.9
tr:W0W4P1_ZYGBA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.62	329	196	9	24	334	259	553	1e-10	74.3
rs:WP_034685923	DNA topoisomerase I [Chryseobacterium piperi].	27.39	303	173	11	36	334	217	476	1e-10	74.3
rs:WP_032131555	DNA topoisomerase I [Weeksella sp. FF8].	24.55	330	211	9	12	336	183	479	1e-10	74.3
rs:WP_012717494	DNA topoisomerase I [Sulfolobus islandicus].	26.09	368	212	16	73	424	279	602	1e-10	74.3
rs:WP_034411083	DNA topoisomerase I [Candidatus Photodesmus katoptron].	23.38	325	201	8	74	386	288	576	1e-10	74.3
tr:A0A0D0SS04_CRYGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.44	287	175	7	73	354	299	551	1e-10	74.7
rs:WP_018046902	hypothetical protein [Nitrospina sp. AB-629-B06].	23.00	426	270	13	47	452	262	649	1e-10	74.3
rs:WP_027201850	DNA topoisomerase I [Butyricimonas virosa].	28.08	260	154	7	77	334	253	481	1e-10	74.3
tr:S2VVK6_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.46	335	186	12	45	354	269	571	1e-10	74.3
rs:WP_012359104	topoisomerase I [Candidatus Phytoplasma australiense].	23.67	431	262	15	42	454	212	593	1e-10	74.3
tr:S7VT95_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.97	267	150	8	77	334	249	479	1e-10	74.3
rs:WP_003946104	MULTISPECIES: DNA topoisomerase I [Rhodococcus].	25.23	329	200	10	41	354	266	563	1e-10	74.7
rs:WP_042446727	DNA topoisomerase I [Rhodococcus erythropolis].	25.23	329	200	10	41	354	266	563	1e-10	74.7
rs:WP_011093844	topoisomerase I [Pectobacterium atrosepticum].	25.06	399	243	14	61	446	268	623	1e-10	74.3
tr:A0A0D0TYE8_CRYGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.44	287	175	7	73	354	299	551	1e-10	74.3
rs:WP_021115833	DNA topoisomerase I [[Haemophilus] parasuis].	26.15	283	172	8	77	356	292	540	1e-10	74.3
rs:WP_015237021	DNA topoisomerase I [Deinococcus peraridilitoris].	25.48	314	185	10	47	344	257	537	1e-10	74.3
tr:M9MAK8_PSEA3	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.62	329	202	11	38	357	1076	1367	1e-10	74.7
rs:WP_040889173	hypothetical protein, partial [Zavarzinella formosa].	24.01	429	246	17	45	446	19	394	1e-10	74.3
tr:A0A086LNK0_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.32	354	238	8	39	386	260	582	1e-10	74.3
rs:WP_039640613	DNA topoisomerase I [Campylobacter lari].	24.68	393	230	16	77	450	255	600	1e-10	74.3
rs:WP_041464266	DNA topoisomerase I [Clavibacter michiganensis].	28.17	323	180	14	77	379	288	578	1e-10	74.3
rs:XP_005647407	prokaryotic type I DNA topoisomerase [Coccomyxa subellipsoidea C-169].	23.92	418	261	13	37	434	257	637	1e-10	74.3
tr:W3VT58_9BASI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.62	329	202	11	38	357	1076	1367	1e-10	74.7
rs:WP_015776591	DNA topoisomerase I [Brachybacterium faecium].	25.07	351	221	8	50	385	266	589	1e-10	74.3
tr:X8JDB7_9HOMO	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EUC61727.1};	24.93	337	198	10	75	393	293	592	1e-10	74.3
tr:A0A077R3R3_9BASI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.69	311	173	10	60	357	294	562	1e-10	74.3
rs:WP_033764451	DNA topoisomerase I [Helicobacter pylori].	24.49	396	233	16	74	450	251	599	1e-10	74.3
rs:WP_008552945	DNA topoisomerase I [Pseudovibrio sp. JE062].	25.06	419	247	14	61	446	244	628	1e-10	74.3
tr:W4LWV6_9DELT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETX02400.1}; Flags: Fragment;	33.33	129	85	1	275	403	11	138	1e-10	73.2
tr:W6MAU3_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.99	304	181	7	61	350	263	536	1e-10	74.3
rs:WP_034574745	DNA topoisomerase I, partial [Helicobacter sanguini].	24.69	397	241	13	77	457	51	405	1e-10	73.9
rs:WP_033147559	DNA topoisomerase I [Prevotella sp. P6B1].	25.87	286	165	7	77	345	252	507	1e-10	74.3
rs:WP_044495257	DNA topoisomerase I [Nesterenkonia sp. NP1].	27.09	347	198	14	70	392	293	608	1e-10	74.3
rs:XP_003601731	DNA topoisomerase [Medicago truncatula].	22.65	287	189	7	66	351	433	687	1e-10	74.3
tr:Q9R6Q0_MYCGL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.60	445	271	16	30	450	248	647	1e-10	74.3
tr:H6R9X3_NOCCG	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.93	341	208	10	32	356	242	550	1e-10	74.3
rs:WP_040157647	DNA topoisomerase I [Mobilicoccus sp. SIT2].	26.55	388	221	15	42	400	252	604	1e-10	74.3
tr:T1B7I0_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EQD68911.1}; Flags: Fragment;	31.01	158	85	4	223	377	96	232	1e-10	71.2
rs:WP_001694606	DNA topoisomerase, partial [Escherichia coli].	31.58	133	81	3	315	443	1	127	1e-10	70.9
rs:XP_012057921	PREDICTED: DNA topoisomerase 3-alpha-like [Atta cephalotes].	23.04	460	266	17	30	449	288	699	1e-10	74.3
tr:A0A0A8I747_CAMLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.68	393	230	16	77	450	254	599	1e-10	74.3
rs:WP_039980762	DNA topoisomerase I [Vibrio sagamiensis].	25.94	320	192	11	77	386	291	575	1e-10	74.3
rs:WP_008279117	DNA topoisomerase I [Roseovarius sp. TM1035].	24.80	488	262	20	34	454	205	654	1e-10	74.3
tr:A0A086PLT6_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.32	354	238	8	39	386	260	582	1e-10	74.3
rs:WP_003657116	topoisomerase I [Moraxella catarrhalis].	25.35	359	214	17	40	384	263	581	1e-10	74.3
tr:A0A086K1Q5_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.82	355	235	9	39	386	243	565	1e-10	74.3
tr:A0A0D0Y1P3_CRYGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.44	287	175	7	73	354	299	551	1e-10	74.3
tr:A0A0D1A1L6_CRYGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.44	287	175	7	73	354	299	551	1e-10	74.3
rs:WP_039432234	DNA topoisomerase I [Porphyromonas gulae].	27.44	266	156	8	77	338	248	480	1e-10	74.3
rs:WP_039808911	DNA topoisomerase I [Nocardia otitidiscaviarum].	25.47	322	184	11	48	354	293	573	1e-10	74.3
rs:WP_028902877	DNA topoisomerase I [Prevotella sp. P6B4].	25.87	286	165	7	77	345	252	507	1e-10	74.3
rs:WP_018636189	DNA topoisomerase I [Frankia sp. BMG5.12].	26.28	293	169	11	77	354	377	637	1e-10	74.3
rs:WP_038186134	DNA topoisomerase I [Vibrio rhizosphaerae].	24.56	395	240	14	68	446	276	628	1e-10	74.3
tr:A0A022R1M4_ERYGU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.92	439	257	21	40	453	255	641	1e-10	74.3
tr:W1Q971_OGAPD	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:ESW97356.1}; EC=5.99.1.2 {ECO:0000313|EMBL:ESW97356.1};	22.92	384	240	11	37	397	258	608	1e-10	73.9
rs:WP_021708677	DNA topoisomerase I [Vibrio azureus].	25.94	320	192	11	77	386	291	575	1e-10	74.3
rs:WP_036870289	DNA topoisomerase I [Prevotella histicola].	24.33	300	181	7	47	334	222	487	1e-10	74.3
tr:X1QZS2_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S25363 {ECO:0000313|EMBL:GAI48794.1}; Flags: Fragment;	29.61	179	116	6	109	281	1	175	1e-10	70.5
rs:WP_013455663	DNA topoisomerase I [Marivirga tractuosa].	28.38	296	174	10	65	352	237	502	1e-10	74.3
rs:WP_021019037	topoisomerase I [Vibrio gazogenes].	24.19	401	234	14	68	446	276	628	1e-10	74.3
tr:K2SJX0_MACPH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.67	304	191	8	39	337	256	526	1e-10	73.9
rs:XP_003072754	DNA topoisomerase III [Encephalitozoon intestinalis ATCC 50506].	22.66	384	250	11	6	380	208	553	1e-10	73.9
rs:WP_003658699	topoisomerase I [Moraxella catarrhalis].	25.35	359	214	17	40	384	263	581	1e-10	74.3
rs:WP_041560585	DNA topoisomerase I, partial [Nocardia farcinica].	24.62	329	202	9	41	354	271	568	1e-10	74.3
rs:WP_031718225	DNA topoisomerase I [Mycobacterium tuberculosis].	25.26	384	230	12	41	399	271	622	1e-10	74.3
rs:WP_017863681	DNA topoisomerase I [Leptospira santarosai].	23.80	437	262	17	40	450	211	602	1e-10	73.9
rs:WP_004474620	DNA topoisomerase I [Leptospira santarosai].	23.80	437	262	17	40	450	211	602	1e-10	73.9
rs:WP_006334965	DNA topoisomerase 1 [Mesorhizobium sp. STM 4661].	25.71	455	252	20	41	452	224	635	1e-10	74.3
tr:A0A0F4WY86_ANAPH	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJZ98756.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KJZ98756.1};	25.96	312	175	11	54	347	239	512	1e-10	73.6
rs:WP_041503327	DNA topoisomerase I [Sanguibacteroides justesenii].	25.37	272	162	8	77	342	253	489	1e-10	74.3
rs:WP_025067094	DNA topoisomerase I [Prevotella denticola].	25.34	292	166	9	77	350	252	509	1e-10	74.3
rs:WP_008247632	topoisomerase I [gamma proteobacterium BDW918].	24.50	404	256	12	60	452	279	644	1e-10	74.3
rs:WP_014217896	DNA topoisomerase I [Niastella koreensis].	24.60	313	204	9	37	346	214	497	1e-10	74.3
rs:WP_036853384	DNA topoisomerase I [Prevotella denticola].	25.34	292	166	9	77	350	252	509	1e-10	73.9
rs:WP_040682714	DNA topoisomerase I, partial [Methanocaldococcus villosus].	25.68	292	169	9	18	294	213	471	1e-10	74.3
tr:K8CQN7_CROSK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.55	290	173	10	166	446	64	322	1e-10	73.9
rs:WP_039291757	DNA topoisomerase I [Pectobacterium atrosepticum].	25.06	399	243	14	61	446	268	623	1e-10	74.3
rs:WP_046377850	DNA topoisomerase I [Rhodococcus erythropolis].	24.92	329	201	10	41	354	266	563	1e-10	74.3
tr:A0A0D0VE76_CRYGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.44	287	175	7	73	354	299	551	1e-10	74.3
rs:XP_008728657	hypothetical protein G647_06111 [Cladophialophora carrionii CBS 160.54].	23.35	394	237	13	45	409	266	623	1e-10	73.9
rs:WP_021105143	DNA topoisomerase I [Propionibacterium granulosum].	25.31	324	191	12	77	379	287	580	1e-10	74.3
tr:Q5Z2Y2_NOCFA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.62	329	202	9	41	354	275	572	1e-10	74.3
rs:WP_004472265	DNA topoisomerase I [Leptospira santarosai].	23.39	436	265	16	40	450	211	602	1e-10	73.9
rs:WP_034905489	DNA topoisomerase I [Campylobacter sp. MIT 97-5078].	25.62	402	221	19	74	450	251	599	1e-10	73.9
rs:WP_047544758	DNA topoisomerase I [Psychroserpens sp. Hel_I_66].	27.31	260	155	7	77	334	249	476	1e-10	73.9
rs:XP_012571821	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Cicer arietinum].	21.79	413	247	14	65	454	221	580	1e-10	73.9
rs:WP_007892424	topoisomerase I [Pantoea sp. GM01].	26.63	323	187	11	77	386	284	569	1e-10	73.9
rs:WP_036010230	DNA topoisomerase I [Leptolyngbya sp. JSC-1].	22.53	435	283	11	24	443	226	621	1e-10	73.9
rs:WP_006170276	DNA topoisomerase I [Synechococcus sp. WH 5701].	25.96	339	217	8	37	370	246	555	1e-10	74.3
rs:XP_008913563	hypothetical protein PPTG_17637 [Phytophthora parasitica INRA-310].	24.43	352	226	10	39	381	262	582	1e-10	74.3
rs:WP_036086741	DNA topoisomerase I [Leptospira weilii].	21.97	437	270	14	40	450	211	602	1e-10	73.9
rs:WP_026209402	DNA topoisomerase I [Corynebacterium caspium].	25.83	302	169	11	77	354	297	567	1e-10	74.3
rs:WP_028669069	DNA topoisomerase I [Runella zeae].	26.33	300	179	10	47	340	222	485	1e-10	73.9
rs:WP_032576955	DNA topoisomerase I, partial [Bacteroides fragilis].	24.11	282	196	8	21	294	186	457	1e-10	73.6
rs:WP_022175297	DNA topoisomerase, partial [Clostridium sp. CAG:557].	27.67	300	169	12	166	451	45	310	1e-10	73.6
tr:E6MQ03_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.86	263	158	7	77	334	269	499	1e-10	73.9
rs:WP_004483035	DNA topoisomerase I [Leptospira santarosai].	23.80	437	262	17	40	450	211	602	1e-10	73.9
rs:XP_008913564	hypothetical protein, variant [Phytophthora parasitica INRA-310].	24.43	352	226	10	39	381	212	532	1e-10	73.9
rs:WP_036425991	DNA topoisomerase I [Mycobacterium sp. 012931].	25.40	378	234	12	41	399	274	622	1e-10	73.9
rs:WP_014944633	DNA topoisomerase I [Chlamydia psittaci].	24.24	396	249	17	69	449	263	622	1e-10	73.9
gp:HG974234_6437	DNA topoisomerase I, plasmid [Pseudomonas aeruginosa]	25.50	404	222	18	77	454	245	595	1e-10	73.9
tr:I9YBT9_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	25.76	295	171	12	166	450	89	345	1e-10	73.6
rs:WP_033420432	DNA topoisomerase I, partial [Nesterenkonia alba].	26.20	332	200	11	70	385	281	583	1e-10	73.9
rs:WP_044079149	DNA topoisomerase I [Prevotella salivae].	25.86	263	158	7	77	334	252	482	1e-10	73.9
rs:WP_011283668	DNA topoisomerase I [Mycoplasma synoviae].	25.76	396	212	16	92	459	272	613	1e-10	73.9
rs:WP_021720800	DNA topoisomerase [Phascolarctobacterium succinatutens].	24.94	413	249	14	63	456	249	619	1e-10	73.9
tr:A0A072V0B5_MEDTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.65	287	189	7	66	351	220	474	1e-10	73.9
rs:WP_038604242	DNA topoisomerase I, partial [Rickettsiales bacterium Ac37b].	24.64	418	252	17	66	452	249	634	1e-10	73.9
rs:WP_038368150	DNA topoisomerase I [Bosea sp. UNC402CLCol].	25.49	412	238	14	77	454	260	636	1e-10	73.9
rs:WP_011102734	DNA topoisomerase I [Tropheryma whipplei].	25.00	340	200	13	30	354	234	533	1e-10	73.9
gp:Z14112_2	DNA topoisomerase I [Bacillus firmus]	28.92	249	144	9	86	324	3	228	1e-10	71.2
rs:WP_040828386	DNA topoisomerase I [Nocardia jiangxiensis].	25.46	326	184	10	47	354	297	581	1e-10	73.9
rs:WP_008270706	DNA topoisomerase I [Flavobacteriales bacterium ALC-1].	26.97	267	150	9	77	334	249	479	1e-10	73.9
rs:WP_009201701	DNA topoisomerase I [Anaerobaculum hydrogeniformans].	22.56	430	272	12	40	452	221	606	1e-10	73.9
rs:WP_025276614	DNA topoisomerase I [Helicobacter pylori].	23.99	396	235	16	74	450	251	599	1e-10	73.9
rs:WP_004276466	DNA topoisomerase I [Campylobacter upsaliensis].	24.81	399	228	17	74	450	252	600	1e-10	73.9
rs:WP_042726447	DNA topoisomerase I, partial [Curtobacterium sp. B8].	26.81	332	178	12	48	354	272	563	1e-10	73.9
rs:WP_043599342	DNA topoisomerase I [Nocardia otitidiscaviarum].	25.47	322	184	11	48	354	293	573	1e-10	73.9
rs:WP_010154970	DNA topoisomerase I [Leucobacter chromiiresistens].	26.46	325	187	11	77	379	295	589	1e-10	73.9
rs:WP_014886238	DNA topoisomerase I [Mycoplasma gallisepticum].	23.82	445	270	17	30	450	248	647	1e-10	73.9
tr:A0A0D0XTS2_CRYGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.44	287	175	7	73	354	299	551	1e-10	73.9
rs:WP_017532806	DNA topoisomerase 1 [Mycoplasma pneumoniae].	23.37	475	301	15	8	456	227	664	1e-10	73.9
rs:WP_004484542	DNA topoisomerase I [Leptospira santarosai].	23.80	437	262	17	40	450	211	602	1e-10	73.6
rs:WP_047424831	DNA topoisomerase I [Chryseobacterium sp. YR480].	27.62	286	164	10	51	334	232	476	1e-10	73.9
tr:G7JBC7_MEDTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.65	287	189	7	66	351	280	534	1e-10	73.9
rs:WP_031794362	DNA topoisomerase III, partial [Staphylococcus aureus].	27.71	166	109	2	35	194	227	387	1e-10	73.2
tr:A0A077LXP7_9MICO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.70	343	191	11	61	378	272	582	1e-10	73.9
tr:A0A080ZA52_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETO63513.1};	24.43	352	226	10	39	381	262	582	1e-10	73.9
tr:A0A0C4E714_MAGP6	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.26	305	189	7	37	333	255	525	1e-10	73.6
rs:XP_002500244	predicted protein [Micromonas sp. RCC299].	21.93	415	269	13	40	434	261	640	1e-10	73.9
rs:WP_016504046	DNA topoisomerase [Candidatus Photodesmus katoptron].	23.38	325	201	8	74	386	288	576	1e-10	73.9
rs:WP_040817503	DNA topoisomerase I, partial [gamma proteobacterium IMCC3088].	27.13	258	152	7	203	452	3	232	1e-10	73.2
tr:A0A080ZA53_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETO63514.1};	24.43	352	226	10	39	381	212	532	1e-10	73.9
rs:WP_036914127	MULTISPECIES: DNA topoisomerase I [Prochlorococcus].	24.15	381	238	9	40	398	249	600	1e-10	73.9
rs:WP_015868991	DNA topoisomerase I [Kosmotoga olearia].	24.75	396	240	14	48	425	222	577	1e-10	73.9
rs:WP_042506202	DNA topoisomerase I [Tropheryma whipplei].	25.00	340	200	13	30	354	234	533	1e-10	73.9
rs:WP_038104331	DNA topoisomerase I [Tropheryma whipplei].	25.00	340	200	13	30	354	234	533	1e-10	73.9
rs:WP_045025600	DNA topoisomerase I [Draconibacterium sp. JN14CK-3].	27.07	266	158	8	73	335	251	483	1e-10	73.9
rs:WP_023528066	DNA topoisomerase I [Streptomycetaceae bacterium MP113-05].	23.78	328	201	11	42	354	270	563	1e-10	73.9
rs:XP_446732	hypothetical protein [Candida glabrata CBS 138].	24.32	370	215	12	39	377	275	610	1e-10	73.6
rs:XP_002946642	hypothetical protein VOLCADRAFT_79203 [Volvox carteri f. nagariensis].	23.19	332	216	9	38	362	261	560	1e-10	73.9
tr:E6QI81_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CBI06946.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI06946.1};	25.17	437	254	16	41	446	216	610	1e-10	73.9
tr:W2YEZ5_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETP32749.1};	24.43	352	226	10	39	381	212	532	1e-10	73.9
rs:XP_005650322	DNA topoisomerase I [Coccomyxa subellipsoidea C-169].	25.57	481	280	19	22	454	209	659	2e-10	73.9
rs:WP_035062284	DNA topoisomerase I, partial [Cellulomonas bogoriensis].	26.14	394	225	14	30	387	244	607	2e-10	73.9
rs:WP_012988731	topoisomerase I [Xenorhabdus bovienii].	25.64	390	236	17	77	452	282	631	2e-10	73.9
tr:W2YDN6_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETP32748.1};	24.43	352	226	10	39	381	262	582	2e-10	73.9
tr:F3L520_9GAMM	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EGG28557.1};	27.13	258	152	7	203	452	2	231	2e-10	73.2
rs:WP_013358013	MULTISPECIES: topoisomerase I [Pantoea].	24.92	305	188	8	77	376	293	561	2e-10	73.9
rs:XP_007213059	hypothetical protein PRUPE_ppa020488mg, partial [Prunus persica].	25.84	329	202	10	18	337	236	531	2e-10	73.6
rs:WP_021678025	DNA topoisomerase, partial [Porphyromonas gingivalis].	29.27	164	111	4	74	236	116	275	2e-10	71.6
rs:XP_004502265	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Cicer arietinum].	21.79	413	247	14	65	454	281	640	2e-10	73.9
rs:WP_045101789	DNA topoisomerase I [Aliivibrio wodanis].	25.32	391	218	15	77	446	290	627	2e-10	73.9
rs:WP_046403146	DNA topoisomerase I [Odoribacter sp. UNK.MGS-12].	25.93	270	159	8	77	340	249	483	2e-10	73.9
rs:WP_015357483	DNA topoisomerase I TopA [Mycobacterium liflandii].	25.40	378	234	12	41	399	274	622	2e-10	73.9
rs:WP_013612667	DNA topoisomerase I [Odoribacter splanchnicus].	25.93	270	159	8	77	340	249	483	2e-10	73.6
rs:WP_004481537	DNA topoisomerase I [Leptospira santarosai].	23.80	437	262	17	40	450	211	602	2e-10	73.6
rs:WP_022884824	DNA topoisomerase I [Glaciibacter superstes].	27.06	303	167	11	77	356	299	570	2e-10	73.9
rs:WP_040773167	DNA topoisomerase I [Nocardia pneumoniae].	25.08	331	202	9	41	356	271	570	2e-10	73.9
rs:WP_045801345	DNA topoisomerase I [Muricauda lutaonensis].	27.40	281	168	8	65	340	238	487	2e-10	73.9
rs:WP_020726831	DNA topoisomerase I [Mycobacterium marinum].	25.40	378	234	12	41	399	274	622	2e-10	73.9
tr:A8U1H8_9PROT	SubName: Full=Possible DNA topoisomerase {ECO:0000313|EMBL:EDP61902.1};	35.82	134	77	3	289	414	1	133	2e-10	72.0
rs:WP_013631854	DNA topoisomerase I [Pseudopedobacter saltans].	26.34	262	163	8	77	335	250	484	2e-10	73.9
rs:WP_041692327	DNA topoisomerase I, partial [Erwinia billingiae].	24.78	448	278	19	19	452	231	633	2e-10	73.9
rs:WP_027466409	DNA topoisomerase I [Curtobacterium sp. UNCCL17].	26.46	378	208	14	31	379	251	587	2e-10	73.9
rs:WP_027712113	DNA topoisomerase I [Dickeya chrysanthemi].	23.56	382	237	11	77	446	286	624	2e-10	73.9
tr:F7K1L0_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGN43773.1};	25.18	282	179	6	179	457	7	259	2e-10	72.4
tr:A0A076H187_9SYNE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.66	339	218	7	37	370	269	578	2e-10	73.9
tr:A0A096CWZ0_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.34	267	162	6	77	334	252	487	2e-10	73.6
tr:C9KMX8_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.06	453	264	18	36	457	247	650	2e-10	73.6
tr:R4PZ44_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.62	329	181	8	47	350	222	508	2e-10	73.6
rs:WP_023794037	DNA topoisomerase [Candidatus Saccharibacteria bacterium RAAC3_TM7_1].	24.51	306	178	7	47	340	222	486	2e-10	73.6
rs:WP_040211709	DNA topoisomerase I [Clostridium sp. MS1].	23.43	431	261	14	47	454	224	608	2e-10	73.6
rs:WP_036882691	DNA topoisomerase I [Prevotella disiens].	24.34	267	162	6	77	334	271	506	2e-10	73.6
rs:WP_046874733	DNA topoisomerase I [Vibrio alginolyticus].	26.25	320	189	11	77	385	291	574	2e-10	73.6
rs:WP_016730808	DNA topoisomerase I [Sulfolobus islandicus].	25.82	368	213	16	73	424	279	602	2e-10	73.6
rs:XP_004502266	PREDICTED: DNA topoisomerase 3-beta isoform X3 [Cicer arietinum].	24.15	294	176	9	65	351	175	428	2e-10	73.6
tr:A0A0B0HQ32_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	35.20	125	77	3	77	199	2	124	2e-10	70.1
rs:WP_022511190	DNA topoisomerase I, partial [Prevotella sp. CAG:617].	28.40	243	143	8	98	338	1	214	2e-10	73.2
rs:WP_047381520	DNA topoisomerase I [Chryseobacterium sp. YR485].	26.01	323	191	11	36	351	217	498	2e-10	73.6
tr:D8MSU2_ERWBE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.78	448	278	19	19	452	231	633	2e-10	73.6
rs:WP_046402617	DNA topoisomerase I [Odoribacter sp. N15.MGS-14].	25.93	270	159	8	77	340	249	483	2e-10	73.6
tr:K1RMM9_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central domain protein {ECO:0000313|EMBL:EKC44784.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EKC44784.1}; Flags: Fragment;	27.93	222	146	6	79	294	29	242	2e-10	71.2
rs:WP_045756029	DNA topoisomerase I, partial [Sphingobacterium sp. PM2-P1-29].	25.67	261	164	5	77	334	95	328	2e-10	73.6
rs:WP_038547907	DNA topoisomerase I [Synechococcus sp. KORDI-100].	25.66	339	218	7	37	370	246	555	2e-10	73.6
tr:N1Q2F9_DOTSN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.82	333	209	9	18	339	237	532	2e-10	73.6
tr:A0A077XXA7_9SPHI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.67	261	164	5	77	334	93	326	2e-10	73.6
rs:WP_020002986	MULTISPECIES: DNA topoisomerase I [Mycoplasma].	25.45	385	209	15	92	452	272	602	2e-10	73.6
rs:WP_044314482	DNA topoisomerase III, partial [Pseudomonas stutzeri].	48.44	64	33	0	65	128	271	334	2e-10	72.0
rs:WP_017067846	topoisomerase I [Vibrio crassostreae].	26.11	383	225	15	77	446	290	627	2e-10	73.6
rs:WP_035347842	DNA topoisomerase [Edaphobacter aggregans].	22.13	470	286	16	19	446	219	650	2e-10	73.6
rs:WP_017199192	DNA topoisomerase I [Arthrobacter sp. M2012083].	26.21	290	174	10	77	354	289	550	2e-10	73.6
rs:WP_012884779	topoisomerase I [Dickeya dadantii].	25.15	338	204	10	61	385	275	576	2e-10	73.6
rs:WP_027138598	DNA topoisomerase I [Gaetbulibacter saemankumensis].	26.89	264	151	8	77	334	249	476	2e-10	73.6
rs:WP_017799901	topoisomerase I [Erwinia toletana].	25.52	388	239	15	77	452	285	634	2e-10	73.6
rs:XP_010414049	PREDICTED: DNA topoisomerase 3-beta-like isoform X2 [Camelina sativa].	22.71	317	205	9	40	351	218	499	2e-10	73.6
rs:WP_022160764	DNA topoisomerase [Odoribacter sp. N54.MGS-14].	26.52	264	153	8	77	334	249	477	2e-10	73.6
tr:A0A077FJB6_9RICK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.64	418	252	17	66	452	249	634	2e-10	73.6
tr:A0A0B4GX59_9HYPO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KID82071.1};	25.00	276	174	6	65	339	306	549	2e-10	73.6
rs:WP_034251254	DNA topoisomerase I, partial [Bifidobacterium crudilactis].	26.87	335	193	11	42	354	261	565	2e-10	73.6
rs:WP_012396656	DNA topoisomerase I [Mycobacterium marinum].	25.40	378	234	12	41	399	274	622	2e-10	73.6
rs:WP_036258305	DNA topoisomerase I [Methylocapsa aurea].	25.39	449	252	16	45	452	228	634	2e-10	73.6
rs:WP_046736800	DNA topoisomerase I [Dehalogenimonas sp. WBC-2].	22.87	481	272	19	33	450	216	660	2e-10	73.6
rs:XP_773035	hypothetical protein CNBJ3110 [Cryptococcus neoformans var. neoformans B-3501A].	25.44	287	175	7	73	354	299	551	2e-10	73.6
tr:A0A086KDL2_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.32	354	238	8	39	386	260	582	2e-10	73.2
rs:WP_014574925	DNA topoisomerase I [Mycoplasma pneumoniae].	23.37	475	301	15	8	456	227	664	2e-10	73.6
tr:W0RS27_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.15	338	199	11	77	401	282	578	2e-10	73.6
rs:WP_021669643	DNA topoisomerase I [Prevotella disiens].	24.34	267	162	6	77	334	271	506	2e-10	73.6
tr:T1KFF4_TETUR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.84	403	265	12	38	424	261	629	2e-10	73.6
rs:WP_017222302	topoisomerase I [Moritella dasanensis].	25.82	395	230	18	77	452	287	637	2e-10	73.6
rs:XP_012455603	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Gossypium raimondii].	24.83	290	179	10	65	351	286	539	2e-10	73.6
rs:WP_020254513	hypothetical protein [Parcubacteria bacterium SCGC AAA036-E14].	22.96	405	253	15	61	451	242	601	2e-10	73.6
tr:A0A090T1A0_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	24.68	393	243	14	65	446	88	438	2e-10	73.6
rs:XP_012843149	PREDICTED: DNA topoisomerase 3-beta [Erythranthe guttatus].	23.92	439	257	21	40	453	255	641	2e-10	73.6
rs:WP_005506017	topoisomerase I [Grimontia hollisae].	24.41	381	234	13	77	446	290	627	2e-10	73.6
rs:WP_032380053	DNA topoisomerase I [Rhodococcus fascians].	26.89	331	192	11	41	354	265	562	2e-10	73.6
rs:XP_008475039	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-beta-1-like [Diaphorina citri].	22.03	354	239	9	37	385	256	577	2e-10	73.6
rs:WP_035612931	DNA topoisomerase I [Hyphomonas johnsonii].	24.65	430	269	12	47	452	231	629	2e-10	73.6
rs:WP_030782197	DNA topoisomerase I [Streptomyces sp. NRRL S-920].	25.26	293	170	11	77	354	298	556	2e-10	73.6
rs:XP_010510116	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Camelina sativa].	22.71	317	205	9	40	351	218	499	2e-10	73.6
tr:J5Q6M3_TRIAS	SubName: Full=DNA topoisomerase 3-beta {ECO:0000313|EMBL:EJT45758.1};	28.44	218	119	6	141	354	480	664	2e-10	73.6
rs:XP_010510118	PREDICTED: DNA topoisomerase 3-beta isoform X4 [Camelina sativa].	22.71	317	205	9	40	351	148	429	2e-10	73.6
rs:WP_017999241	DNA topoisomerase I [Paracoccus sp. N5].	24.75	404	241	13	77	454	259	625	2e-10	73.6
rs:WP_036456737	DNA topoisomerase I [Mycobacterium marinum].	25.40	378	234	12	41	399	274	622	2e-10	73.6
rs:WP_012769871	MULTISPECIES: topoisomerase I [Dickeya].	23.56	382	237	11	77	446	286	624	2e-10	73.6
rs:WP_016941328	topoisomerase I [Dickeya zeae].	25.74	338	202	12	61	385	275	576	2e-10	73.6
rs:WP_023404807	DNA topoisomerase I [Vibrio halioticoli].	24.55	391	221	14	77	446	290	627	2e-10	73.6
rs:XP_002480564	DNA topoisomerase III, putative [Talaromyces stipitatus ATCC 10500].	25.25	305	185	9	40	337	261	529	2e-10	73.2
rs:WP_025791346	DNA topoisomerase I [Prevotella histicola].	24.00	300	182	7	47	334	222	487	2e-10	73.6
rs:XP_010510117	PREDICTED: DNA topoisomerase 3-beta isoform X3 [Camelina sativa].	22.71	317	205	9	40	351	162	443	2e-10	73.6
rs:WP_004479531	DNA topoisomerase I [Leptospira santarosai].	23.80	437	262	17	40	450	211	602	2e-10	73.2
rs:XP_010414048	PREDICTED: DNA topoisomerase 3-beta-like isoform X1 [Camelina sativa].	22.71	317	205	9	40	351	258	539	2e-10	73.6
rs:XP_010510115	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Camelina sativa].	22.71	317	205	9	40	351	258	539	2e-10	73.6
rs:WP_026320092	DNA topoisomerase I [Bacteroides barnesiae].	26.54	260	159	6	77	334	249	478	2e-10	73.6
rs:WP_040636070	DNA topoisomerase I [Mitsuokella multacida].	24.06	453	264	18	36	457	254	657	2e-10	73.6
tr:A0A0B2WZX3_9HYPO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KHN99603.1};	25.27	281	165	8	65	338	242	484	2e-10	73.2
rs:WP_007022807	topoisomerase I [Neptuniibacter caesariensis].	23.40	376	243	11	77	446	295	631	2e-10	73.6
sp:TOP1_MYCPN	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	23.53	476	299	15	8	456	227	664	2e-10	73.2
rs:WP_038925913	DNA topoisomerase I [Dickeya zeae].	25.74	338	202	12	61	385	275	576	2e-10	73.6
rs:WP_032404601	DNA topoisomerase I [Rhodococcus fascians].	26.89	331	192	11	41	354	265	562	2e-10	73.6
rs:WP_017105774	topoisomerase I [Vibrio tasmaniensis].	24.74	380	234	13	77	446	290	627	2e-10	73.6
rs:WP_036888796	DNA topoisomerase I [Prevotella aurantiaca].	25.37	268	158	7	77	334	271	506	2e-10	73.6
rs:WP_022339030	DNA topoisomerase [Bacteroides sp. CAG:714].	26.54	260	159	6	77	334	249	478	2e-10	73.6
rs:WP_006583074	DNA topoisomerase I [Thermanaerovibrio velox].	24.60	439	253	17	40	452	258	644	2e-10	73.2
rs:WP_037149138	DNA topoisomerase I [Rhodococcus fascians].	26.89	331	192	11	41	354	265	562	2e-10	73.6
tr:A0A077MCJ1_9MICO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.07	351	196	13	77	402	285	600	2e-10	73.6
rs:WP_040000940	DNA topoisomerase I [Dickeya chrysanthemi].	25.00	380	234	13	77	446	286	624	2e-10	73.6
rs:WP_033123370	DNA topoisomerase I [Helicobacter pylori].	24.30	395	235	16	74	450	251	599	2e-10	73.2
rs:WP_044382392	DNA topoisomerase I [Streptomyces cyaneogriseus].	25.95	289	173	10	77	354	311	569	2e-10	73.6
rs:WP_041534416	DNA topoisomerase I [Petrotoga mobilis].	23.17	423	255	15	28	428	199	573	2e-10	73.2
rs:XP_012455605	PREDICTED: DNA topoisomerase 3-beta isoform X3 [Gossypium raimondii].	24.83	290	179	10	65	351	195	448	2e-10	73.2
rs:WP_038904398	DNA topoisomerase I [Dickeya zeae].	25.74	338	202	12	61	385	275	576	2e-10	73.6
rs:WP_044631157	DNA topoisomerase I [Tamlana sedimentorum].	26.89	264	151	8	77	334	249	476	2e-10	73.2
tr:A0A061PJJ8_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.56	320	188	11	77	385	292	575	2e-10	73.6
tr:X0TCY4_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_L03150 {ECO:0000313|EMBL:GAF85181.1}; Flags: Fragment;	26.20	332	194	13	133	452	2	294	2e-10	72.4
rs:WP_039936927	DNA topoisomerase I [Leptospira terpstrae].	21.97	437	257	13	60	449	224	623	2e-10	73.2
rs:WP_037620502	DNA topoisomerase, partial [Streptococcus parauberis].	31.84	179	113	4	52	226	7	180	2e-10	69.7
tr:A0A023CUK7_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	22.90	428	250	19	57	457	82	456	2e-10	72.8
tr:A0A024GYV1_9MICC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.62	325	205	10	42	354	254	550	2e-10	73.6
rs:WP_037176028	DNA topoisomerase I [Rhodococcus fascians].	26.89	331	192	11	41	354	265	562	2e-10	73.6
rs:WP_046008750	DNA topoisomerase I [Oleispira antarctica].	23.94	376	240	11	77	446	295	630	2e-10	73.6
rs:WP_026003064	DNA topoisomerase I [Rhodococcus sp. R1101].	26.96	293	168	10	77	354	301	562	2e-10	73.6
rs:WP_009089965	topoisomerase I [Pantoea sp. Sc1].	23.99	396	235	12	77	452	284	633	2e-10	73.2
rs:WP_024124916	DNA topoisomerase I TopA [Thermosynechococcus sp. NK55a].	25.00	356	224	10	41	385	249	572	2e-10	73.2
rs:WP_008545028	DNA topoisomerase I [Candidatus Pelagibacter sp. HTCC7211].	24.71	433	263	16	51	454	234	632	2e-10	73.2
tr:Q1PYZ6_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.21	418	258	15	61	458	249	623	2e-10	73.2
rs:WP_047258839	DNA topoisomerase I [Corynebacterium uterequi].	25.30	328	190	12	41	351	263	552	2e-10	73.6
rs:WP_032391302	DNA topoisomerase I [Rhodococcus fascians].	26.89	331	192	11	41	354	265	562	2e-10	73.6
gp:LN831790_3259	DNA topoisomerase 1 [Streptomyces leeuwenhoekii]	25.95	289	173	10	77	354	299	557	2e-10	73.2
rs:WP_018613933	hypothetical protein [Segetibacter koreensis].	25.16	310	196	7	36	342	214	490	2e-10	73.2
rs:WP_032406609	DNA topoisomerase I [Rhodococcus fascians].	26.89	331	192	11	41	354	265	562	2e-10	73.6
rs:WP_025133176	DNA topoisomerase I [Leucobacter sp. PH1c].	26.01	296	174	9	77	356	295	561	2e-10	73.2
rs:WP_014343005	DNA topoisomerase III [Klebsiella pneumoniae].	41.89	74	43	0	36	109	251	324	2e-10	72.4
rs:WP_032384044	DNA topoisomerase I [Rhodococcus fascians].	26.89	331	192	11	41	354	265	562	2e-10	73.6
rs:WP_046516925	DNA topoisomerase I, partial [Cryomorphaceae bacterium ASP10-05a].	24.48	290	188	5	47	333	217	478	2e-10	73.2
rs:WP_027395008	DNA topoisomerase I [Aquimarina latercula].	27.11	273	156	11	68	334	241	476	2e-10	73.2
gp:LN483332_510	prokaryotic type i dna topoisomerase [Xanthophyllomyces dendrorhous]	25.00	336	186	9	37	353	262	550	2e-10	73.2
rs:WP_022354894	DNA topoisomerase [Bacteroides sp. CAG:875].	26.67	270	157	8	77	340	249	483	2e-10	73.2
tr:K1RIM1_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC43504.1}; Flags: Fragment;	30.64	173	100	5	278	445	99	256	2e-10	71.6
rs:WP_010303834	DNA topoisomerase I [Synechococcus sp. CB0101].	26.38	345	213	9	37	370	246	560	2e-10	73.2
rs:WP_038913983	DNA topoisomerase I [Dickeya zeae].	25.74	338	202	12	61	385	275	576	2e-10	73.2
rs:WP_047209062	DNA topoisomerase [Streptococcus agalactiae].	24.14	348	208	14	48	385	258	559	2e-10	72.8
rs:WP_012534462	DNA topoisomerase [Aliivibrio fischeri].	23.60	322	209	9	93	387	316	627	2e-10	73.2
rs:WP_040556296	DNA topoisomerase I [Prevotella disiens].	24.34	267	162	6	77	334	271	506	2e-10	73.2
tr:F7CBA4_CALJA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.76	435	276	17	40	455	289	682	2e-10	73.2
rs:WP_028832336	DNA topoisomerase I, partial [Proteobacteria bacterium JGI 0000113-E04].	24.01	279	174	7	60	334	175	419	2e-10	73.2
rs:WP_004493941	DNA topoisomerase I [Leptospira santarosai].	23.80	437	262	17	40	450	211	602	2e-10	72.8
rs:WP_008039550	DNA topoisomerase I [Bartonella tamiae].	23.82	445	262	16	47	452	230	636	2e-10	73.2
tr:A0A0F3QRC6_RICAM	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJV95225.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KJV95225.1};	24.80	367	217	15	106	449	16	346	2e-10	72.8
rs:WP_007295121	DNA topoisomerase, partial [delta proteobacterium MLMS-1].	25.19	262	156	8	207	452	10	247	2e-10	72.4
rs:WP_007844344	MULTISPECIES: DNA topoisomerase I [Chryseobacterium].	26.91	301	177	10	36	334	217	476	2e-10	73.2
tr:A9BI47_PETMO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.17	423	255	15	28	428	218	592	2e-10	73.2
rs:WP_031726084	DNA topoisomerase I [Mycobacterium tuberculosis].	25.07	383	232	11	41	399	271	622	2e-10	73.2
rs:WP_032388239	DNA topoisomerase I [Rhodococcus fascians].	26.89	331	192	11	41	354	265	562	3e-10	73.2
rs:XP_012455604	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Gossypium raimondii].	24.83	290	179	10	65	351	243	496	3e-10	73.2
rs:WP_022079531	DNA topoisomerase [Acetobacter sp. CAG:267].	26.68	416	245	17	65	454	246	627	3e-10	73.2
rs:WP_032399637	DNA topoisomerase I [Rhodococcus fascians].	26.89	331	192	11	41	354	265	562	3e-10	73.2
rs:WP_032364536	DNA topoisomerase I [Rhodococcus fascians].	26.89	331	192	11	41	354	265	562	3e-10	73.2
rs:WP_027494469	MULTISPECIES: DNA topoisomerase I [Rhodococcus].	26.89	331	192	11	41	354	265	562	3e-10	73.2
rs:WP_032386019	DNA topoisomerase I [Rhodococcus fascians].	26.89	331	192	11	41	354	265	562	3e-10	73.2
tr:E1KUI6_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.34	267	162	6	77	334	266	501	3e-10	73.2
rs:WP_028982117	DNA topoisomerase I [Sporocytophaga myxococcoides].	25.52	290	184	7	47	334	219	478	3e-10	73.2
rs:WP_030004516	DNA topoisomerase I [Acholeplasma brassicae].	25.69	401	224	14	76	452	246	596	3e-10	72.8
rs:WP_048316699	DNA topoisomerase I [Rhodococcus fascians].	26.89	331	192	11	41	354	265	562	3e-10	73.2
rs:WP_041607638	DNA topoisomerase I [Halobacteroides halobius].	22.61	429	267	14	48	456	233	616	3e-10	72.8
rs:WP_038373706	DNA topoisomerase I [Brachybacterium phenoliresistens].	25.08	315	198	9	50	354	265	551	3e-10	73.2
rs:WP_028892457	DNA topoisomerase I [Tenacibaculum sp. 47A_GOM-205m].	26.45	310	186	10	60	364	232	504	3e-10	73.2
rs:WP_022479784	DNA topoisomerase I [Prevotella sp. CAG:891].	26.49	268	161	8	77	340	252	487	3e-10	73.2
rs:WP_023034502	DNA topoisomerase I [Propionibacterium sp. KPL1844].	26.23	324	188	13	77	379	287	580	3e-10	73.2
rs:WP_043718443	DNA topoisomerase I [Nocardia asiatica].	25.54	325	186	10	47	356	287	570	3e-10	73.2
tr:W7HVY4_9PEZI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.08	311	186	8	40	339	258	532	3e-10	72.8
rs:WP_022108248	DNA topoisomerase [Clostridium sp. CAG:138].	24.09	465	253	17	46	449	227	652	3e-10	72.8
rs:WP_016419510	DNA topoisomerase I [Capnocytophaga granulosa].	25.16	314	186	8	35	334	198	476	3e-10	73.2
rs:WP_026950130	DNA topoisomerase I [Algoriphagus mannitolivorans].	25.00	272	173	6	65	334	237	479	3e-10	72.8
rs:WP_006619329	DNA topoisomerase I subunit omega [Arthrospira platensis].	25.23	333	202	11	25	344	230	528	3e-10	73.2
tr:Z9JPX2_9MICO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.08	315	198	9	50	354	266	552	3e-10	73.2
rs:WP_005522405	DNA topoisomerase I [Corynebacterium matruchotii].	26.89	331	200	12	31	351	260	558	3e-10	73.2
tr:N1W1T2_9LEPT	SubName: Full=Putative DNA topoisomerase I {ECO:0000313|EMBL:EMY63225.1};	21.97	437	257	13	60	449	197	596	3e-10	72.8
tr:F3CCA9_PSESG	SubName: Full=Topoisomerase {ECO:0000313|EMBL:EGH16901.1}; Flags: Fragment;	33.33	114	76	0	33	146	151	264	3e-10	70.5
rs:WP_026541356	DNA topoisomerase I [Arthrobacter nicotinovorans].	25.86	290	175	10	77	354	289	550	3e-10	73.2
rs:WP_046222745	DNA topoisomerase I [Vibrio sp. ECSMB14106].	26.42	386	220	17	77	446	290	627	3e-10	73.2
rs:WP_035210349	hypothetical protein, partial [Acidithiobacillus thiooxidans].	22.49	418	247	14	61	459	235	594	3e-10	72.8
rs:WP_032632047	hypothetical protein, partial [Pseudomonas syringae].	40.85	71	42	0	106	176	2	72	3e-10	67.4
rs:WP_032373810	DNA topoisomerase I [Rhodococcus fascians].	26.89	331	192	11	41	354	265	562	3e-10	73.2
tr:H0GYF0_SACCK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.61	328	184	9	56	357	243	536	3e-10	72.8
rs:WP_011077240	DNA topoisomerase I [Mycoplasma penetrans].	22.16	379	243	8	86	449	282	623	3e-10	72.8
rs:WP_002639752	DNA topoisomerase I [Myxococcus sp. (contaminant ex DSM 436)].	22.17	451	273	12	41	452	295	706	3e-10	72.8
rs:WP_032577106	DNA topoisomerase I, partial [Bacteroides fragilis].	23.08	286	192	6	114	395	1	262	3e-10	70.9
rs:WP_021856504	DNA topoisomerase [Firmicutes bacterium CAG:555].	24.82	427	264	13	47	454	229	617	3e-10	72.8
tr:L0K918_HALHC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.61	429	267	14	48	456	228	611	3e-10	72.8
rs:WP_025018184	DNA topoisomerase I [Bacteroides sartorii].	25.52	286	166	7	77	345	253	508	3e-10	72.8
rs:WP_017055037	topoisomerase I [Vibrio kanaloae].	26.42	386	220	17	77	446	290	627	3e-10	72.8
rs:WP_014683881	DNA topoisomerase I [Deinococcus gobiensis].	25.16	318	195	10	40	344	255	542	3e-10	73.2
rs:XP_012187028	hypothetical protein PHSY_001006 [Pseudozyma hubeiensis SY62].	25.38	331	191	12	41	357	274	562	3e-10	73.2
rs:WP_002695179	DNA topoisomerase I [Treponema phagedenis].	23.01	465	273	14	36	449	226	656	3e-10	72.8
rs:WP_043534481	DNA topoisomerase I [Actinomyces sp. MS2].	26.73	333	191	13	77	384	289	593	3e-10	72.8
rs:WP_019845082	topoisomerase I [Dickeya zeae].	25.15	338	204	10	61	385	275	576	3e-10	72.8
rs:WP_045354101	topoisomerase I, partial [Lactobacillus plantarum].	33.33	123	80	1	277	397	4	126	3e-10	70.1
rs:WP_032369316	DNA topoisomerase I [Rhodococcus fascians].	26.89	331	192	11	41	354	265	562	3e-10	72.8
rs:WP_039683440	DNA topoisomerase I [Deinococcus swuensis].	24.84	322	199	9	36	344	246	537	3e-10	72.8
rs:WP_032067815	DNA topoisomerase I, partial [Acinetobacter baumannii].	26.99	289	170	12	166	446	11	266	3e-10	72.4
tr:A0A060PQD6_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	25.42	295	172	12	166	450	89	345	3e-10	72.4
rs:WP_017062103	topoisomerase I [Vibrio crassostreae].	26.11	383	225	15	77	446	290	627	3e-10	72.8
tr:A0A0B4F270_METAN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KID68280.1}; Flags: Fragment;	25.18	282	166	8	65	339	306	549	3e-10	72.8
tr:W6MQ22_9ASCO	SubName: Full=Genomic scaffold, Kuraishia_capsulata_scaffold_5 {ECO:0000313|EMBL:CDK28428.1};	24.17	360	213	12	45	377	260	586	3e-10	72.4
rs:WP_039913780	DNA topoisomerase I [Cellvibrio mixtus].	25.06	431	255	17	42	452	260	642	3e-10	72.8
tr:A0A0E8TK36_STREE	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CRG01035.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRG01035.1};	25.66	226	135	7	236	457	3	199	3e-10	70.5
tr:U3TRG9_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.54	276	161	9	77	348	284	524	3e-10	72.4
rs:WP_023639723	topoisomerase I [Dickeya zeae].	25.15	338	204	10	61	385	275	576	3e-10	72.8
tr:N1R4S4_AEGTA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.27	445	231	18	39	452	235	604	3e-10	72.8
tr:A0A0E0NQ40_ORYRU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.64	423	229	14	39	452	270	607	3e-10	72.8
rs:WP_014806151	DNA topoisomerase I [Anaerobaculum mobile].	22.25	427	277	13	40	452	221	606	3e-10	72.8
tr:A0A074XH50_9PEZI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.75	268	168	5	73	339	302	539	3e-10	72.8
tr:W4QCD4_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.73	148	97	4	32	175	229	373	3e-10	72.0
rs:WP_041321546	DNA topoisomerase I [Rothia dentocariosa].	25.00	324	195	10	46	354	263	553	3e-10	72.8
tr:E3H0I0_ROTDC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	324	195	10	46	354	267	557	3e-10	72.8
rs:WP_027462956	DNA topoisomerase I [Deinococcus ficus].	24.92	321	192	10	40	344	250	537	3e-10	72.8
rs:WP_038908015	DNA topoisomerase I [Dickeya zeae].	25.74	338	202	12	61	385	275	576	3e-10	72.8
tr:A0A094SR49_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KGA21208.1};	26.96	319	183	11	77	378	290	575	3e-10	72.8
rs:WP_044577397	DNA topoisomerase I [Arthrobacter sp. A3].	25.69	327	202	11	42	354	260	559	3e-10	72.8
tr:A0A066VU73_9HOMO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDN42125.1}; Flags: Fragment;	24.63	337	199	11	75	393	108	407	3e-10	72.8
rs:WP_048512015	DNA topoisomerase I [Chryseobacterium sp. FH2].	26.91	301	177	10	36	334	217	476	3e-10	72.8
rs:XP_003290405	hypothetical protein DICPUDRAFT_37309 [Dictyostelium purpureum].	24.84	318	196	9	40	351	272	552	3e-10	72.8
rs:XP_010447600	PREDICTED: uncharacterized protein LOC104730175 isoform X3 [Camelina sativa].	23.74	438	263	14	61	458	688	1094	3e-10	72.8
tr:A0A0B4G022_9HYPO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KID79810.1}; Flags: Fragment;	25.53	282	165	9	65	339	283	526	3e-10	72.4
rs:XP_010786073	PREDICTED: DNA topoisomerase 3-alpha-like, partial [Notothenia coriiceps].	26.69	251	139	5	59	294	334	554	3e-10	72.4
rs:WP_029137196	DNA topoisomerase I [Nakamurella lactea].	28.52	298	164	11	77	354	296	564	4e-10	72.8
rs:WP_035270855	DNA topoisomerase I, partial [Desulfonatronum thiodismutans].	23.61	432	271	12	39	452	214	604	4e-10	72.8
tr:A0A097STQ1_9MOLU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.11	380	240	9	88	450	286	626	4e-10	72.4
rs:XP_010447598	PREDICTED: uncharacterized protein LOC104730175 isoform X1 [Camelina sativa].	23.74	438	263	14	61	458	689	1095	4e-10	72.8
rs:WP_017888707	hypothetical protein [Curtobacterium flaccumfaciens].	26.26	358	201	12	48	379	267	587	4e-10	72.8
rs:WP_034672551	DNA topoisomerase I [Chryseobacterium formosense].	27.24	301	176	10	36	334	217	476	4e-10	72.8
rs:WP_012718809	DNA topoisomerase I [Sulfolobus islandicus].	25.82	368	213	16	73	424	279	602	4e-10	72.4
rs:WP_034945873	DNA topoisomerase I [Gilliamella apicola].	25.94	320	194	10	43	356	252	534	4e-10	72.8
rs:WP_035217216	hypothetical protein, partial [Acidithiobacillus thiooxidans].	22.49	418	247	14	61	459	235	594	4e-10	72.4
rs:WP_028872666	DNA topoisomerase I [Psychroserpens burtonensis].	26.09	276	170	7	61	334	233	476	4e-10	72.8
tr:G6AHM1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.67	300	183	7	47	334	228	493	4e-10	72.4
rs:WP_019483173	DNA topoisomerase I [Arthrobacter sp. TB 23].	24.86	358	224	10	42	379	261	593	4e-10	72.8
rs:WP_044061963	hypothetical protein, partial [Escherichia coli].	25.00	208	143	2	31	233	256	455	4e-10	72.0
rs:WP_040559679	DNA topoisomerase I [Prevotella histicola].	23.67	300	183	7	47	334	222	487	4e-10	72.4
tr:A4CRQ0_SYNPV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.23	366	225	13	26	378	258	591	4e-10	72.8
tr:Q7V627_PROMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.88	381	239	9	40	398	266	617	4e-10	72.8
rs:WP_011457582	DNA topoisomerase I [Chlamydophila felis].	24.12	398	247	16	69	449	263	622	4e-10	72.8
tr:B7ATQ2_9FIRM	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EEC57036.1};	25.29	257	154	8	207	457	6	230	4e-10	70.9
rs:WP_010259203	DNA topoisomerase I [Treponema primitia].	23.30	455	256	16	49	449	238	653	4e-10	72.4
tr:K2A8D8_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.77	428	261	15	41	452	239	621	4e-10	72.4
rs:WP_029274672	DNA topoisomerase I [Pedobacter borealis].	25.90	305	179	8	36	335	219	481	4e-10	72.4
rs:WP_008720283	Topoisomerase IA [Rhodococcus sp. AW25M09].	27.11	343	184	14	69	402	277	562	4e-10	72.4
tr:T5AB99_OPHSC	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EQL02720.1};	25.25	301	192	8	37	335	254	523	4e-10	72.4
rs:XP_011652536	PREDICTED: uncharacterized protein LOC101210581 [Cucumis sativus].	22.32	448	268	15	47	450	571	982	4e-10	72.8
rs:XP_010447599	PREDICTED: uncharacterized protein LOC104730175 isoform X2 [Camelina sativa].	23.74	438	263	14	61	458	689	1095	4e-10	72.8
rs:WP_004470045	DNA topoisomerase I [Leptospira santarosai].	23.57	437	263	17	40	450	211	602	4e-10	72.4
rs:WP_024753357	DNA topoisomerase I [Treponema phagedenis].	23.01	465	273	14	36	449	226	656	4e-10	72.4
rs:WP_012797070	DNA topoisomerase I [Capnocytophaga ochracea].	27.51	269	160	8	68	334	241	476	4e-10	72.4
rs:WP_037287953	DNA topoisomerase I [Rothia dentocariosa].	25.00	324	195	10	46	354	263	553	4e-10	72.8
rs:XP_005949422	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X4 [Haplochromis burtoni].	23.51	319	193	9	40	347	261	539	4e-10	72.0
tr:H0ABU3_HALSG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.54	164	94	7	79	237	1	154	4e-10	68.9
rs:WP_017618511	DNA topoisomerase I [Nocardiopsis gilva].	24.56	338	203	12	60	379	295	598	4e-10	72.4
rs:WP_017076459	topoisomerase I [Vibrio splendidus].	25.62	320	193	10	77	386	290	574	4e-10	72.4
tr:X1NF35_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S13387 {ECO:0000313|EMBL:GAI42632.1}; Flags: Fragment;	26.44	261	136	8	110	356	23	241	4e-10	70.1
rs:WP_008522909	DNA topoisomerase I [Jonquetella anthropi].	23.33	433	269	13	47	458	347	737	4e-10	72.4
rs:WP_042538864	DNA topoisomerase I [Curtobacterium flaccumfaciens].	26.26	358	201	12	48	379	267	587	4e-10	72.4
rs:WP_004491528	DNA topoisomerase I [Leptospira santarosai].	23.17	436	266	16	40	450	211	602	4e-10	72.4
tr:V5AV88_TRYCR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESS64730.1};	23.28	378	240	12	73	434	287	630	4e-10	72.4
rs:WP_035300573	DNA topoisomerase III, partial [Clostridium sp. ATCC BAA-442].	35.66	143	80	4	286	425	1	134	4e-10	69.7
tr:A0A078C0P1_BRANA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.48	477	280	17	26	458	588	1023	4e-10	72.8
tr:W1DE29_KLEPN	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CDL07786.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDL07786.1};	28.35	194	111	4	166	356	22	190	4e-10	70.9
rs:WP_038843894	DNA topoisomerase I, partial [Campylobacter coli].	26.33	300	167	12	166	452	11	269	4e-10	71.2
tr:G1VGY8_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGW46164.1};	31.74	167	105	4	260	425	1	159	4e-10	69.7
tr:H3G7Y5_PHYRM	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblProtists:Phyra54032}; Flags: Fragment;	24.47	331	213	9	54	377	277	577	4e-10	72.4
rs:XP_011000015	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Populus euphratica].	23.02	391	238	14	65	434	246	594	4e-10	72.4
rs:XP_007703913	hypothetical protein COCSADRAFT_163916 [Bipolaris sorokiniana ND90Pr].	25.96	312	180	10	39	339	259	530	4e-10	72.4
rs:WP_018768948	DNA topoisomerase I [Arthrobacter sp. 162MFSha1.1].	26.21	290	174	10	77	354	289	550	4e-10	72.4
rs:WP_044626838	DNA topoisomerase I [Tamlana nanhaiensis].	26.52	264	152	8	77	334	249	476	4e-10	72.4
rs:WP_010143115	DNA topoisomerase I [Citricoccus sp. CH26A].	29.15	295	162	12	77	356	296	558	4e-10	72.4
rs:XP_011000014	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Populus euphratica].	22.93	410	244	16	65	453	285	643	4e-10	72.4
rs:WP_005942398	DNA topoisomerase I [Bacteroides massiliensis].	26.14	264	162	7	77	338	253	485	4e-10	72.4
tr:K4E7B0_TRYCR	SubName: Full=DNA topoisomerase III, putative {ECO:0000313|EMBL:EKG06290.1};	23.28	378	240	12	73	434	287	630	4e-10	72.4
rs:WP_003797809	DNA topoisomerase I [Arthrobacter globiformis].	25.52	290	176	10	77	354	289	550	4e-10	72.4
rs:WP_023418078	MULTISPECIES: DNA topoisomerase I [Streptomyces].	25.26	293	170	11	77	354	298	556	4e-10	72.4
rs:WP_045275221	DNA topoisomerase I [Microbacterium ketosireducens].	27.55	323	181	12	45	354	262	544	4e-10	72.4
tr:K2F0M1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.53	427	246	16	47	452	245	620	4e-10	72.4
rs:WP_038005493	DNA topoisomerase I [Synechococcus sp. WH 7805].	26.23	366	225	13	26	378	233	566	4e-10	72.4
rs:WP_037620543	hypothetical protein, partial [Streptococcus parauberis].	41.00	100	50	3	230	328	2	93	4e-10	67.4
rs:WP_047139490	DNA topoisomerase I [Streptomyces sp. KE1].	25.26	293	170	11	77	354	298	556	4e-10	72.4
tr:A0A086KE27_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.32	316	191	11	40	347	184	462	4e-10	72.0
rs:WP_037984289	DNA topoisomerase I [Tannerella sp. oral taxon BU063].	26.01	346	214	13	65	384	241	570	4e-10	72.4
rs:WP_027748357	DNA topoisomerase I [Streptomyces sp. CNH287].	25.60	293	169	11	77	354	304	562	4e-10	72.4
rs:WP_046101912	DNA topoisomerase I [Pantoea anthophila].	23.99	396	235	12	77	452	284	633	4e-10	72.4
rs:WP_006233149	topoisomerase I [Photobacterium profundum].	26.08	395	227	19	77	452	290	638	4e-10	72.4
rs:WP_040493737	DNA topoisomerase I [Ilumatobacter nonamiensis].	27.00	337	198	10	60	377	251	558	4e-10	72.4
rs:WP_017111054	topoisomerase I [Vibrio tasmaniensis].	25.00	328	185	11	77	386	290	574	4e-10	72.4
rs:WP_030698222	DNA topoisomerase I [Streptomyces griseus].	25.26	293	170	11	77	354	298	556	4e-10	72.4
rs:WP_047470413	DNA topoisomerase I [Streptomyces sp. M10].	25.26	293	170	11	77	354	298	556	4e-10	72.4
rs:WP_042507044	DNA topoisomerase I [Tropheryma whipplei].	24.71	340	201	13	30	354	234	533	5e-10	72.4
rs:WP_037978261	DNA topoisomerase I [Tannerella sp. oral taxon BU063].	28.06	278	163	10	65	338	241	485	5e-10	72.4
tr:A0A090KU15_STRRB	SubName: Full=DNA topoisomerase 3-beta {ECO:0000313|EMBL:CEF61010.1};	23.82	340	215	12	55	386	285	588	5e-10	72.0
rs:WP_004763567	DNA topoisomerase I [Leptospira kirschneri].	22.75	444	277	14	31	450	197	598	5e-10	72.0
tr:W2MF57_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETM34940.1};	24.15	352	227	10	39	381	212	532	5e-10	72.4
rs:WP_027697125	DNA topoisomerase I [Vibrio litoralis].	26.06	353	185	13	69	394	276	579	5e-10	72.4
rs:WP_027305561	DNA topoisomerase I [Campylobacter cuniculorum].	24.75	400	227	17	74	450	252	600	5e-10	72.0
rs:WP_019668894	DNA topoisomerase I [Eudoraea adriatica].	24.34	341	219	9	1	334	170	478	5e-10	72.4
rs:WP_023133708	DNA topoisomerase I [Rothia aeria].	25.00	324	195	10	46	354	263	553	5e-10	72.4
rs:WP_010643779	DNA topoisomerase I [Streptomyces sp. S4].	25.26	293	170	11	77	354	298	556	5e-10	72.4
rs:WP_022801505	DNA topoisomerase I [Deinococcus sp. 2009].	24.92	321	192	10	40	344	250	537	5e-10	72.4
rs:XP_009313180	putative DNA topoisomerase III, partial [Trypanosoma grayi].	22.57	412	270	12	39	434	252	630	5e-10	72.4
rs:WP_012351072	DNA topoisomerase [Pyrobaculum neutrophilum].	26.21	351	200	12	47	380	251	559	5e-10	72.0
rs:WP_013139485	DNA topoisomerase I [Segniliparus rotundus].	26.51	298	167	9	77	354	303	568	5e-10	72.4
tr:A0A0D9NTR7_METAN	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:KJK77419.1};	25.18	282	166	8	65	339	306	549	5e-10	72.0
rs:XP_004039715	hypothetical protein IMG5_012580, partial [Ichthyophthirius multifiliis].	20.80	375	263	8	29	399	305	649	5e-10	72.0
rs:WP_038110921	DNA topoisomerase I [Tropheryma whipplei].	24.71	340	201	13	30	354	234	533	5e-10	72.4
rs:WP_033239415	DNA topoisomerase I [Streptomyces griseus].	25.26	293	170	11	77	354	298	556	5e-10	72.4
rs:WP_031178411	DNA topoisomerase I [Streptomyces sp. NRRL B-3253].	25.26	293	170	11	77	354	298	556	5e-10	72.4
rs:WP_018470360	MULTISPECIES: DNA topoisomerase I [Streptomyces].	25.26	293	170	11	77	354	298	556	5e-10	72.4
rs:WP_003949667	MULTISPECIES: DNA topoisomerase I [Streptomyces].	25.26	293	170	11	77	354	298	556	5e-10	72.4
rs:WP_030309838	DNA topoisomerase I [Streptomyces albidoflavus].	25.26	293	170	11	77	354	298	556	5e-10	72.4
rs:WP_019496473	hypothetical protein [Calothrix sp. PCC 7103].	25.00	360	215	13	40	387	244	560	5e-10	72.0
rs:WP_038519001	DNA topoisomerase I [Moraxella catarrhalis].	25.35	359	214	17	40	384	263	581	5e-10	72.4
tr:A0A044UT61_ONCVO	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:OVOC7692};	23.48	345	223	9	40	377	353	663	5e-10	72.4
tr:W2FWD4_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETK75057.1};	24.15	352	227	10	39	381	262	582	5e-10	72.4
rs:WP_045749618	DNA topoisomerase I [Acholeplasma oculi].	24.28	416	247	12	57	454	227	592	5e-10	72.0
rs:WP_012711318	DNA topoisomerase I [Sulfolobus islandicus].	25.68	366	216	16	73	424	279	602	5e-10	72.0
tr:S7WCX6_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.32	316	191	11	40	347	267	545	5e-10	72.0
tr:S8G2P0_FOMPI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.42	389	237	13	25	393	247	598	5e-10	72.4
tr:A0A0F3NIL9_ANAPH	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJV66749.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KJV66749.1};	26.69	296	161	11	54	331	239	496	5e-10	71.6
rs:XP_002631605	Hypothetical protein CBG20786, partial [Caenorhabditis briggsae].	23.68	380	244	13	12	379	229	574	5e-10	72.0
rs:WP_041385137	DNA topoisomerase I [Prochlorococcus marinus].	23.88	381	239	9	40	398	249	600	5e-10	72.0
rs:WP_002354010	hypothetical protein, partial [Enterococcus faecium].	43.68	87	46	1	279	365	1	84	5e-10	69.3
tr:A0A0D0XBT8_CRYGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.09	287	176	7	73	354	299	551	5e-10	72.0
rs:WP_043441853	DNA topoisomerase I [Arthrobacter sp. L77].	23.94	355	226	12	42	379	261	588	5e-10	72.0
tr:A0A086L562_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.00	316	192	11	40	347	267	545	5e-10	72.0
rs:WP_035335751	DNA topoisomerase I [Dokdonia sp. PRO95].	27.59	290	160	11	62	340	235	485	5e-10	72.0
rs:WP_006898127	DNA topoisomerase I [Gordonia sihwensis].	26.79	336	195	13	66	379	286	592	5e-10	72.0
tr:A0A086QKJ5_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.32	316	191	11	40	347	267	545	5e-10	72.0
rs:XP_002321105	DNA topoisomerase family protein [Populus trichocarpa].	23.02	391	238	14	65	434	258	606	5e-10	72.0
rs:XP_007806726	DNA topoisomerase III [Metarhizium acridum CQMa 102].	25.00	276	174	6	65	339	312	555	5e-10	72.0
rs:WP_008666735	DNA topoisomerase I [Rhodopirellula europaea].	25.71	280	176	7	77	351	314	566	5e-10	72.0
rs:WP_008661721	DNA topoisomerase I [Rhodopirellula europaea].	25.71	280	176	7	77	351	314	566	5e-10	72.0
rs:WP_043055226	DNA topoisomerase I, partial [Micrococcus luteus].	25.27	376	229	12	35	385	259	607	5e-10	72.0
tr:A0A086KLT8_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.32	316	191	11	40	347	267	545	6e-10	72.0
rs:WP_036888889	DNA topoisomerase I, partial [Porphyromonas crevioricanis].	26.75	228	155	6	60	280	262	484	6e-10	71.6
tr:E1YZG1_9PORP	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:EFK61037.1}; Flags: Fragment;	35.56	135	80	5	60	193	282	410	6e-10	71.2
rs:WP_013073533	DNA topoisomerase I [Zunongwangia profunda].	26.58	301	178	9	36	334	218	477	6e-10	72.0
rs:XP_001611286	DNA topoisomerase family protein [Babesia bovis].	24.79	351	217	11	40	378	266	581	6e-10	72.0
rs:WP_022633521	DNA topoisomerase [Dickeya solani].	24.70	421	258	16	40	446	249	624	6e-10	72.0
rs:WP_006888270	DNA topoisomerase I [Rothia aeria].	24.62	325	201	9	45	354	258	553	6e-10	72.0
sp:TOP1_BUCAI	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	22.77	347	222	10	51	387	257	567	6e-10	72.0
rs:WP_038891121	DNA topoisomerase III, partial [Vibrio campbellii].	35.64	101	63	1	26	126	238	336	6e-10	70.9
tr:J9H515_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EJX08960.1};	24.63	268	166	7	77	340	253	488	6e-10	72.0
rs:WP_019598710	DNA topoisomerase I [Rhodonellum psychrophilum].	25.00	292	187	7	47	335	218	480	6e-10	72.0
rs:XP_012078427	PREDICTED: DNA topoisomerase 3-beta [Jatropha curcas].	24.69	324	190	13	40	351	257	538	6e-10	72.0
rs:WP_007025070	DNA topoisomerase I [Saccharomonospora paurometabolica].	26.03	365	221	12	40	384	272	607	6e-10	72.0
rs:WP_021987910	DNA topoisomerase [Odoribacter sp. CAG:788].	25.47	267	164	6	77	340	249	483	6e-10	72.0
rs:WP_029353009	DNA topoisomerase I [Mesorhizobium ciceri].	24.89	450	262	19	41	452	224	635	6e-10	72.0
rs:WP_036301804	DNA topoisomerase I [Methylotenera sp. L2L1].	25.60	414	241	17	60	449	246	616	6e-10	72.0
rs:XP_002366301	DNA topoisomerase III alpha, putative [Toxoplasma gondii ME49].	25.32	316	191	11	40	347	267	545	6e-10	71.6
rs:WP_011096652	DNA topoisomerase I [Tropheryma whipplei].	24.71	340	201	13	30	354	234	533	6e-10	72.0
rs:WP_040926792	DNA topoisomerase I [Saccharomonospora marina].	25.00	328	204	10	40	354	248	546	6e-10	72.0
rs:WP_010080299	DNA topoisomerase I [Micrococcus luteus].	25.27	376	229	12	35	385	259	607	6e-10	72.0
rs:WP_044225531	DNA topoisomerase I [Flammeovirga pacifica].	27.54	305	174	11	36	334	218	481	6e-10	72.0
tr:H5X247_9PSEU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	328	204	10	40	354	325	623	6e-10	72.0
tr:A0A074YQ60_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KEQ96187.1};	24.76	307	194	6	40	339	263	539	6e-10	71.6
rs:WP_040794088	DNA topoisomerase I [Nocardia higoensis].	25.81	310	182	10	60	354	274	550	6e-10	72.0
tr:A0A0D0UN27_CRYGA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.09	287	176	7	73	354	299	551	6e-10	72.0
tr:R2W309_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOI37143.1};	41.76	91	50	1	275	365	9	96	6e-10	69.3
rs:WP_022278767	hypothetical protein [Dorea formicigenerans CAG:28].	29.66	145	91	4	149	286	23	163	6e-10	68.2
rs:WP_029147941	DNA topoisomerase I [Methylophilus sp. 5].	24.52	416	245	15	60	449	246	618	6e-10	72.0
rs:WP_038892183	DNA topoisomerase III, partial [Vibrio campbellii].	35.64	101	63	1	26	126	238	336	6e-10	70.5
tr:A0A0E0IGT2_ORYNI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.74	438	244	15	39	451	322	694	6e-10	72.0
rs:XP_011652538	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC101210823 [Cucumis sativus].	22.74	453	276	15	47	458	588	1007	6e-10	72.0
tr:C9M7U6_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.09	433	270	13	47	458	214	604	6e-10	71.6
rs:WP_026356103	DNA topoisomerase I [Pannonibacter phragmitetus].	25.82	426	238	18	68	452	252	640	6e-10	72.0
rs:WP_006045293	DNA topoisomerase I [Prevotella pallens].	25.94	266	159	6	77	334	271	506	6e-10	72.0
rs:WP_028899889	DNA topoisomerase I [Prevotella sp. HJM029].	24.20	314	199	8	26	334	203	482	6e-10	71.6
rs:WP_019214705	hypothetical protein [Clostridiales bacterium 9401234].	25.18	425	252	15	48	452	228	606	6e-10	71.6
tr:J6Y720_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJX56984.1}; Flags: Fragment;	36.28	113	66	2	210	322	1	107	6e-10	67.0
rs:WP_000681411	DNA topoisomerase I [Helicobacter pylori].	24.94	429	256	17	41	450	218	599	6e-10	71.6
rs:WP_043685774	DNA topoisomerase I [Nocardia abscessus].	25.54	325	186	10	47	356	287	570	6e-10	72.0
rs:WP_034530646	DNA topoisomerase I, partial [Parabacteroides sp. 20_3].	35.56	135	80	5	60	193	263	391	7e-10	70.9
gp:MTU40159_1	topoisomerase I [Mycobacterium tuberculosis]	25.00	372	224	12	52	399	287	627	7e-10	72.0
tr:D7U4C0_VITVI	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:CBI37517.3};	24.68	308	179	9	166	451	63	339	7e-10	71.6
rs:XP_003881018	DNA topoisomerase, related [Neospora caninum Liverpool].	23.62	326	214	8	30	351	298	592	7e-10	72.0
tr:M4E5G3_BRARP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.74	438	261	15	54	450	604	1009	7e-10	72.0
rs:WP_023104907	hypothetical protein, partial [Pseudomonas aeruginosa].	25.58	258	145	8	221	459	16	245	7e-10	69.3
rs:WP_047452631	DNA topoisomerase I [Chryseobacterium sp. OV715].	26.25	301	179	10	36	334	217	476	7e-10	71.6
rs:WP_017850207	DNA topoisomerase I [Leptospira interrogans].	22.72	449	275	17	31	450	197	602	7e-10	71.6
rs:XP_009137997	PREDICTED: uncharacterized protein LOC103862037 isoform X1 [Brassica rapa].	23.74	438	261	15	54	450	603	1008	7e-10	72.0
rs:WP_047398591	DNA topoisomerase I [Chryseobacterium sp. YR460].	26.58	301	178	10	36	334	217	476	7e-10	71.6
rs:WP_022712311	DNA topoisomerase I [Pseudochrobactrum sp. AO18b].	25.71	420	238	15	70	452	253	635	7e-10	71.6
rs:WP_003009917	DNA topoisomerase I [Leptospira weilii].	22.02	436	271	16	40	449	211	603	7e-10	71.6
tr:G1WVF4_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGX69669.1};	29.85	134	84	3	160	286	33	163	7e-10	68.2
rs:WP_018775034	MULTISPECIES: DNA topoisomerase I [Arthrobacter].	26.99	326	195	11	77	385	289	588	7e-10	71.6
tr:R4MMD1_MYCTX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	25.33	375	221	12	53	399	7	350	7e-10	71.6
rs:WP_026532947	DNA topoisomerase I [Arthrobacter sp. H41].	25.23	329	198	11	77	384	296	597	7e-10	71.6
rs:WP_004799485	DNA topoisomerase I [[Eubacterium] dolichum].	24.42	434	248	18	47	452	225	606	7e-10	71.6
rs:WP_034737625	DNA topoisomerase I [Chryseobacterium indologenes].	27.39	303	173	12	36	334	217	476	7e-10	71.6
rs:WP_026555994	DNA topoisomerase I [Arthrobacter sp. 35W].	24.80	367	223	12	42	384	260	597	7e-10	71.6
rs:WP_043994823	DNA topoisomerase I [Moritella sp. PE36].	24.92	313	184	10	77	377	294	567	7e-10	71.6
tr:A0A090P7C7_9VIBR	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAK84997.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAK84997.1};	30.54	167	88	5	189	354	18	157	7e-10	68.6
rs:WP_007902332	DNA topoisomerase I [Prevotella stercorea].	26.09	276	160	8	77	338	252	497	7e-10	71.6
rs:XP_009137998	PREDICTED: uncharacterized protein LOC103862037 isoform X2 [Brassica rapa].	23.74	438	261	15	54	450	601	1006	7e-10	72.0
rs:WP_027374086	DNA topoisomerase I [Chryseobacterium sp. UNC8MFCol].	27.39	303	173	12	36	334	217	476	7e-10	71.6
rs:WP_005524983	DNA topoisomerase I [Corynebacterium matruchotii].	24.62	329	210	9	31	351	260	558	7e-10	71.6
rs:WP_016338588	DNA topoisomerase I [Spiroplasma chrysopicola].	22.78	439	259	12	61	452	233	638	7e-10	71.6
rs:WP_034061439	DNA topoisomerase I [Lacinutrix sp. PAMC 27137].	27.31	260	156	7	77	334	249	477	7e-10	71.6
rs:XP_012214509	PREDICTED: DNA topoisomerase 3-beta-1 [Linepithema humile].	23.34	347	215	12	37	370	258	566	7e-10	71.6
rs:WP_026937567	DNA topoisomerase I [Gulosibacter molinativorax].	23.90	318	192	9	60	356	267	555	7e-10	71.6
rs:WP_034727019	DNA topoisomerase I [Chryseobacterium sp. JM1].	26.25	301	179	10	36	334	217	476	7e-10	71.6
tr:A6FH32_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.92	313	184	10	77	377	287	560	7e-10	71.6
rs:WP_016761066	DNA topoisomerase I [Leptospira weilii].	21.92	438	269	17	40	450	211	602	7e-10	71.2
rs:WP_014242696	hypothetical protein, partial [Azospirillum brasilense].	32.14	196	112	9	198	376	1	192	7e-10	70.1
rs:WP_044227149	DNA topoisomerase I [Phaeodactylibacter xiamenensis].	26.64	259	149	9	77	328	253	477	7e-10	71.6
tr:M4C198_HYAAE	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblProtists:HpaP812836};	24.83	302	193	6	54	351	294	565	8e-10	71.2
rs:WP_029739158	DNA topoisomerase I, partial [Cloacimonetes bacterium SCGC AAA252-K16].	23.71	350	200	12	47	377	235	536	8e-10	71.2
rs:WP_009057117	DNA topoisomerase I [Nitritalea halalkaliphila].	26.25	301	182	8	47	340	218	485	8e-10	71.6
rs:WP_041639329	DNA topoisomerase III, partial [Anoxybacillus flavithermus].	36.05	86	55	0	36	121	233	318	8e-10	70.1
rs:WP_044658889	DNA topoisomerase I [Micrococcus sp. MS-ASIII-49].	25.73	342	205	11	35	354	259	573	8e-10	71.6
rs:WP_019246107	DNA topoisomerase I [Candidatus Alistipes marseilloanorexicus].	25.00	308	192	8	35	340	217	487	8e-10	71.6
rs:WP_027454770	DNA topoisomerase I [Prevotella brevis].	24.75	295	186	8	47	334	222	487	8e-10	71.6
rs:WP_036059798	DNA topoisomerase I [Leptospira sp. P2653].	21.92	438	269	17	40	450	211	602	8e-10	71.2
tr:S9UXJ5_9TRYP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.00	328	209	7	82	403	295	591	8e-10	71.6
tr:A0A0D1PJJ0_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.50	366	219	13	30	376	232	566	8e-10	71.6
rs:WP_015469497	DNA topoisomerase I [Bdellovibrio exovorus].	24.42	303	196	7	47	344	269	543	8e-10	71.6
rs:WP_037235776	DNA topoisomerase I [Rothia dentocariosa].	25.00	324	195	10	46	354	263	553	8e-10	71.6
rs:WP_041369758	DNA topoisomerase I, partial [Nakamurella multipartita].	25.35	359	220	11	36	377	259	586	8e-10	71.6
rs:WP_004363587	DNA topoisomerase I [Prevotella nigrescens].	25.75	268	157	7	77	334	252	487	8e-10	71.6
rs:WP_004005452	DNA topoisomerase I [Rothia dentocariosa].	24.69	324	196	10	46	354	263	553	8e-10	71.6
rs:WP_040201559	DNA topoisomerase I, partial [Klebsiella pneumoniae].	26.89	264	160	8	187	446	1	235	8e-10	70.9
rs:WP_043058862	DNA topoisomerase I [Mesorhizobium sp. UASWS1009].	26.50	366	219	13	30	376	247	581	8e-10	71.6
rs:XP_001930451	DNA topoisomerase 3-beta [Pyrenophora tritici-repentis Pt-1C-BFP].	25.65	269	156	7	73	334	300	531	8e-10	71.2
rs:WP_039738802	DNA topoisomerase I, partial [Saccharomonospora halophila].	26.03	365	221	12	40	384	282	617	8e-10	71.6
rs:WP_017192448	hypothetical protein [Milkweed yellows phytoplasma].	21.93	424	268	11	47	454	218	594	8e-10	71.2
rs:WP_048505518	DNA topoisomerase I [Chryseobacterium angstadtii].	25.97	308	180	11	51	351	232	498	8e-10	71.6
rs:WP_011141022	DNA topoisomerase I [Gloeobacter violaceus].	23.75	421	265	11	40	439	236	621	9e-10	71.2
tr:S6EZ85_ZYGB2	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.60	356	216	10	24	357	259	580	9e-10	71.2
rs:WP_047097084	DNA topoisomerase I [Chryseobacterium indologenes].	26.91	301	177	10	36	334	217	476	9e-10	71.6
rs:WP_013602276	DNA topoisomerase I [Arthrobacter phenanthrenivorans].	24.77	323	207	10	42	354	254	550	9e-10	71.6
rs:WP_019628805	topoisomerase I [Moritella marina].	25.63	394	232	17	77	452	294	644	9e-10	71.6
tr:C8X984_NAKMY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.35	359	220	11	36	377	259	586	9e-10	71.6
rs:WP_036499076	DNA topoisomerase I, partial [Mycoplasma testudinis].	22.25	391	243	12	86	454	278	629	9e-10	71.2
tr:H6RHI0_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.18	274	168	9	65	335	238	477	9e-10	71.2
tr:M6ADH4_9LEPT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.92	438	269	17	40	450	212	603	9e-10	71.2
rs:WP_011585715	DNA topoisomerase I [Cytophaga hutchinsonii].	26.82	302	188	9	39	334	210	484	9e-10	71.2
rs:XP_005846276	hypothetical protein CHLNCDRAFT_53167 [Chlorella variabilis].	24.24	396	240	16	74	453	294	645	9e-10	71.2
rs:WP_004634250	DNA topoisomerase I [Gemella morbillorum].	22.30	417	264	12	53	452	231	604	9e-10	71.2
tr:A0A0D3DH53_BRAOL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.39	466	278	16	26	450	1109	1536	9e-10	71.6
rs:WP_004994534	DNA topoisomerase I [Peanut witches'-broom phytoplasma].	24.42	385	227	12	90	457	261	598	9e-10	71.2
rs:WP_029355145	DNA topoisomerase I [Bosea sp. 117].	25.84	476	275	18	20	454	199	637	9e-10	71.2
rs:WP_045639399	DNA topoisomerase I [Flavobacteriales bacterium BRH_c54].	25.86	263	159	8	77	335	249	479	9e-10	71.2
tr:A0A086QAR6_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.32	316	191	11	40	347	267	545	9e-10	71.2
rs:WP_012603610	topoisomerase I [Vibrio tasmaniensis].	25.26	380	232	15	77	446	290	627	9e-10	71.2
rs:WP_011360529	DNA topoisomerase I [Synechococcus sp. CC9902].	24.48	339	216	8	40	370	249	555	9e-10	71.2
rs:WP_026552082	DNA topoisomerase I [Arthrobacter sp. H20].	24.40	373	230	12	31	379	249	593	9e-10	71.2
rs:WP_035344662	DNA topoisomerase I [Acholeplasma modicum].	22.90	441	265	16	30	452	210	593	9e-10	71.2
rs:WP_026534214	DNA topoisomerase I [Arthrobacter sp. H14].	24.39	328	208	8	42	356	269	569	9e-10	71.2
tr:S2JN43_MUCC1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.60	339	212	9	59	387	281	582	9e-10	71.2
rs:WP_032008633	DNA topoisomerase I, partial [Acinetobacter baumannii].	27.53	287	164	13	177	452	4	257	9e-10	69.7
tr:A0A0D2A347_9PEZI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.12	333	208	9	18	339	40	335	9e-10	70.9
rs:WP_045089368	DNA topoisomerase I [Porphyromonadaceae bacterium ING2-E5B].	26.02	269	154	7	77	337	252	483	9e-10	71.2
rs:WP_028269930	DNA topoisomerase I [Arthrobacter sp. UNC362MFTsu5.1].	26.21	290	174	10	77	354	292	553	1e-09	71.2
rs:WP_029444934	DNA topoisomerase I [Cellulophaga baltica].	25.52	290	184	6	47	334	219	478	1e-09	71.2
rs:XP_007822225	DNA topoisomerase [Metarhizium robertsii ARSEF 23].	25.18	282	166	8	65	339	283	526	1e-09	71.2
rs:WP_029513500	DNA topoisomerase I [Mycoplasma primatum].	24.24	396	229	13	78	452	254	599	1e-09	71.2
rs:WP_009846346	topoisomerase I [Vibrio sp. MED222].	25.26	380	232	15	77	446	290	627	1e-09	71.2
rs:WP_017089558	topoisomerase I [Vibrio splendidus].	25.85	383	226	15	77	446	290	627	1e-09	71.2
rs:WP_046242733	DNA topoisomerase I [Hymenobacter sp. MIMtkLc17].	26.26	297	184	8	45	334	217	485	1e-09	71.2
rs:XP_955385	DNA topoisomerase iii [Theileria annulata strain Ankara].	21.93	374	240	11	45	402	247	584	1e-09	70.9
rs:WP_005268646	DNA topoisomerase I [Arthrobacter crystallopoietes].	25.95	316	195	10	77	379	295	584	1e-09	71.2
rs:WP_038060592	hypothetical protein, partial [Thermodesulfobacterium commune].	25.74	338	199	12	67	393	246	542	1e-09	70.9
tr:X1IRQ6_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S19347 {ECO:0000313|EMBL:GAH84402.1}; Flags: Fragment;	33.15	181	93	8	278	454	12	168	1e-09	68.2
rs:WP_046400358	DNA topoisomerase III, partial [Staphylococcus aureus].	29.88	164	105	5	289	450	1	156	1e-09	68.6
rs:WP_037148031	topoisomerase I [Rhodococcus fascians].	26.72	378	198	17	79	439	284	599	1e-09	71.2
rs:WP_023801090	DNA topoisomerase I [Mesorhizobium sp. L48C026A00].	25.06	447	265	18	41	452	224	635	1e-09	71.2
tr:A0A090RJ49_9GAMM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL07512.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL07512.1};	40.00	85	50	1	164	247	1	85	1e-09	66.2
rs:XP_001417013	predicted protein, partial [Ostreococcus lucimarinus CCE9901].	25.15	330	207	11	37	351	270	574	1e-09	70.9
tr:A0A009FA84_ACIBA	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EXA75264.1}; Flags: Fragment;	27.53	287	164	13	177	452	4	257	1e-09	69.7
rs:WP_021775997	DNA topoisomerase I [Jonquetella sp. BV3C21].	23.09	433	270	13	47	458	347	737	1e-09	71.2
rs:XP_819023	DNA topoisomerase III [Trypanosoma cruzi strain CL Brener].	23.81	378	238	13	73	434	287	630	1e-09	71.2
rs:WP_040665938	DNA topoisomerase I, partial [Nitrolancea hollandica].	23.93	326	201	9	41	347	136	433	1e-09	70.5
tr:A0A0F4YLE9_TALEM	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:KKA18940.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KKA18940.1};	27.04	270	157	8	73	337	295	529	1e-09	70.9
rs:WP_040506588	DNA topoisomerase I [Leptospira wolbachii].	22.30	435	255	12	61	449	240	637	1e-09	70.9
rs:WP_007339188	DNA topoisomerase I [Rhodopirellula baltica].	25.71	280	176	7	77	351	314	566	1e-09	71.2
rs:WP_007334156	DNA topoisomerase I [Rhodopirellula baltica].	25.71	280	176	7	77	351	314	566	1e-09	71.2
rs:WP_044069760	hypothetical protein [Pseudomonas aeruginosa].	25.50	404	222	19	77	454	245	595	1e-09	70.9
rs:WP_007328430	DNA topoisomerase I [Rhodopirellula baltica].	25.71	280	176	7	77	351	314	566	1e-09	71.2
rs:WP_008993939	DNA topoisomerase I [Novosphingobium sp. Rr 2-17].	25.69	436	262	16	41	452	222	619	1e-09	71.2
tr:A0A0A1V1B1_9HYPO	SubName: Full=DNA topoisomerase domain protein {ECO:0000313|EMBL:EXV03939.1};	25.18	282	166	8	65	339	292	535	1e-09	70.9
rs:WP_008655482	MULTISPECIES: DNA topoisomerase I [Bacteroides].	25.00	260	163	6	77	334	253	482	1e-09	71.2
rs:WP_007841944	DNA topoisomerase I [Bacteroides dorei].	25.00	260	163	6	77	334	253	482	1e-09	71.2
rs:WP_036255616	DNA topoisomerase I [Methylocapsa acidiphila].	25.39	445	253	16	47	452	230	634	1e-09	71.2
rs:WP_019388230	DNA topoisomerase I [Arenitalea lutea].	26.10	295	173	10	61	346	233	491	1e-09	71.2
rs:WP_016961327	topoisomerase I [Enterovibrio norvegicus].	25.00	376	238	13	77	446	290	627	1e-09	71.2
rs:WP_033873339	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	33.61	122	72	3	337	458	2	114	1e-09	67.0
rs:WP_007854957	DNA topoisomerase I [Bacteroides dorei].	25.00	260	163	6	77	334	253	482	1e-09	71.2
rs:WP_045026640	DNA topoisomerase I [Photobacterium phosphoreum].	26.77	325	179	14	42	354	258	535	1e-09	71.2
rs:WP_027387037	DNA topoisomerase I [Chryseobacterium gregarium].	26.92	286	166	10	51	334	232	476	1e-09	71.2
rs:WP_009222712	DNA topoisomerase, partial [Peptoniphilus sp. oral taxon 386].	26.09	299	170	9	69	354	251	511	1e-09	70.9
rs:WP_040864648	DNA topoisomerase I [Nocardia exalbida].	25.54	325	186	10	47	356	287	570	1e-09	71.2
rs:WP_047812879	DNA topoisomerase I [Rhodopirellula sp. K833].	25.76	295	181	8	68	351	275	542	1e-09	71.2
rs:WP_021747026	DNA topoisomerase III [Leptotrichia wadei].	24.23	392	246	14	72	450	270	623	1e-09	70.9
rs:WP_014325425	DNA topoisomerase I [Mycoplasma pneumoniae].	23.16	475	302	15	8	456	227	664	1e-09	70.9
rs:WP_013185913	DNA topoisomerase I [Croceibacter atlanticus].	26.80	306	170	11	36	334	218	476	1e-09	71.2
rs:WP_039879571	DNA topoisomerase I [Jonquetella anthropi].	23.09	433	270	13	47	458	347	737	1e-09	71.2
rs:XP_008882019	DNA topoisomerase family protein [Hammondia hammondi].	24.44	311	200	8	40	347	267	545	1e-09	71.2
rs:WP_036796725	DNA topoisomerase I [Porphyrobacter sp. HL-46].	24.41	426	261	14	52	452	233	622	1e-09	71.2
tr:W7E2Q4_COCVI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.30	336	197	12	18	339	234	529	1e-09	70.9
rs:WP_007847280	DNA topoisomerase I [Bacteroides dorei].	25.00	260	163	6	77	334	253	482	1e-09	71.2
rs:WP_047788555	DNA topoisomerase I [Tenacibaculum mesophilum].	27.93	290	165	11	65	346	238	491	1e-09	71.2
tr:Q4MMD9_BACCE	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:AJI07793.1};	30.83	133	90	2	36	167	244	375	1e-09	70.1
rs:WP_017099940	topoisomerase I [Vibrio tasmaniensis].	25.53	380	231	15	77	446	290	627	1e-09	71.2
rs:WP_007834608	DNA topoisomerase I [Bacteroides dorei].	25.00	260	163	6	77	334	253	482	1e-09	70.9
rs:WP_016479051	DNA topoisomerase I [Capnocytophaga sp. oral taxon 336].	27.14	269	161	8	68	334	241	476	1e-09	70.9
rs:WP_009217720	DNA topoisomerase I [Bacteroidetes oral taxon 274].	27.44	266	157	7	77	337	263	497	1e-09	70.9
rs:WP_031841774	hypothetical protein [Vibrio parahaemolyticus].	30.94	139	90	4	35	170	251	386	1e-09	70.1
rs:WP_027155146	DNA topoisomerase I [Mesorhizobium sp. WSM2561].	24.67	450	263	19	41	452	224	635	1e-09	71.2
tr:A0A078CBA8_BRANA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.39	466	278	16	26	450	569	996	1e-09	71.2
rs:WP_002333472	hypothetical protein, partial [Enterococcus faecium].	31.84	179	113	4	52	226	120	293	1e-09	69.3
rs:WP_008990855	DNA topoisomerase I [Galbibacter marinus].	26.44	261	156	7	77	334	249	476	1e-09	70.9
tr:G9P528_HYPAI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHK41268.1};	23.71	329	203	10	18	335	229	520	1e-09	70.9
tr:A0A0D1YK20_9PEZI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.12	333	208	9	18	339	89	384	1e-09	70.5
rs:WP_040556917	DNA topoisomerase I [Prevotella nigrescens].	25.75	268	157	7	77	334	252	487	1e-09	70.9
tr:M3JWC9_CANMX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EMG47260.1};	23.46	341	206	8	56	378	276	579	1e-09	70.9
rs:WP_038604253	DNA topoisomerase I [Corynebacterium atypicum].	22.94	327	210	9	42	354	266	564	1e-09	71.2
rs:WP_027638117	DNA topoisomerase I [Clostridium cadaveris].	23.49	430	260	14	48	454	225	608	1e-09	70.9
rs:WP_036386129	DNA topoisomerase I [Muricauda sp. MAR_2010_75].	25.08	295	187	7	43	334	215	478	1e-09	70.9
rs:WP_002856321	DNA topoisomerase I [Micrococcus luteus].	25.44	342	206	11	35	354	259	573	1e-09	70.9
tr:S8D4C5_9LAMI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.70	467	288	16	31	458	247	679	1e-09	70.9
rs:WP_027846908	DNA topoisomerase I [Mastigocoleus testarum].	22.47	396	248	10	26	401	226	582	1e-09	70.9
tr:H7ENR1_9SPIO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.94	436	265	16	41	452	258	646	1e-09	70.9
tr:R2AMY6_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOF89568.1};	41.76	91	50	1	275	365	9	96	1e-09	68.6
rs:WP_020762913	DNA topoisomerase I [Leptospira kirschneri].	22.30	444	279	14	31	450	197	598	1e-09	70.9
rs:WP_040843203	DNA topoisomerase I [Treponema saccharophilum].	22.94	436	265	16	41	452	243	631	1e-09	70.9
rs:WP_032808023	topoisomerase I, partial [Oenococcus oeni].	33.33	120	78	1	280	397	1	120	1e-09	68.2
rs:WP_032212518	DNA topoisomerase III, partial [Escherichia coli].	32.04	103	70	0	37	139	245	347	1e-09	69.7
tr:A0A098LAU1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.17	290	185	7	47	334	186	445	1e-09	70.9
rs:WP_040661207	DNA topoisomerase I [Oscillibacter ruminantium].	23.81	420	261	12	55	454	236	616	1e-09	70.9
rs:WP_008674276	DNA topoisomerase I [Bacteroides sp. 9_1_42FAA].	25.00	260	163	6	77	334	253	482	1e-09	70.9
rs:WP_012137309	DNA topoisomerase I subunit omega [Marinobacter lipolyticus].	23.35	424	267	14	36	446	255	633	1e-09	70.9
rs:WP_037017484	DNA topoisomerase I [Rhizobiales bacterium YIM 77505].	24.45	454	262	17	34	452	227	634	1e-09	70.9
rs:WP_021828753	DNA topoisomerase I [Chlamydia gallinacea].	24.01	404	245	17	66	449	261	622	1e-09	70.9
rs:WP_045538949	DNA topoisomerase I [Gordonia sp. no. 9].	26.49	336	196	12	66	379	286	592	1e-09	70.9
rs:XP_007737879	DNA topoisomerase III [Capronia epimyces CBS 606.96].	23.14	376	237	10	41	395	261	605	1e-09	70.5
rs:WP_035837563	DNA topoisomerase I [Cryobacterium roopkundense].	26.73	303	168	11	77	356	292	563	1e-09	70.9
rs:WP_006254729	DNA topoisomerase I [Alloprevotella tannerae].	26.93	323	178	11	45	345	223	509	1e-09	70.9
tr:A0A0B0HYH2_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	36.36	88	56	0	34	121	229	316	1e-09	69.7
rs:WP_003690280	DNA topoisomerase I [Lactobacillus mali].	22.72	427	250	19	55	454	246	619	1e-09	70.9
rs:WP_043777938	hypothetical protein, partial [Deinococcus ficus].	27.04	355	209	12	45	387	255	571	1e-09	70.5
rs:WP_020325470	hypothetical protein, partial [Pseudomonas syringae].	34.78	115	71	2	319	432	2	113	1e-09	67.4
tr:F9DBT9_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.75	268	157	7	77	334	271	506	1e-09	70.9
rs:WP_002686763	DNA topoisomerase I [Bergeyella zoohelcum].	25.99	304	173	11	37	334	218	475	1e-09	70.9
rs:WP_011933781	DNA topoisomerase I [Synechococcus sp. WH 7803].	25.55	364	230	11	26	378	233	566	1e-09	70.9
tr:R9A4C2_9LEPT	SubName: Full=Putative DNA topoisomerase I {ECO:0000313|EMBL:EOQ96952.1};	22.30	435	255	12	61	449	198	595	1e-09	70.5
tr:M5TT54_9PLAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.07	280	175	7	77	351	290	542	1e-09	70.9
rs:WP_046352421	DNA topoisomerase I [Janthinobacterium sp. B9-8].	25.12	430	262	15	43	452	228	617	1e-09	70.9
rs:WP_045458631	DNA topoisomerase I [Sporocytophaga myxococcoides].	25.17	290	185	7	47	334	219	478	1e-09	70.9
tr:A0A0C9ZPS5_9HOMO	SubName: Full=Unplaced genomic scaffold scaffold_10, whole genome shotgun sequence {ECO:0000313|EMBL:KIK28059.1};	26.00	250	144	6	166	404	381	600	1e-09	70.9
rs:WP_018023156	hypothetical protein [Corynebacterium ulceribovis].	23.24	327	210	8	41	354	265	563	1e-09	70.9
rs:WP_014687466	DNA topoisomerase I [Actinoplanes sp. SE50/110].	25.93	324	191	12	47	354	266	556	1e-09	70.9
rs:WP_041990434	DNA topoisomerase I [Capnocytophaga cynodegmi].	25.80	283	172	9	56	334	228	476	1e-09	70.9
rs:WP_036965781	DNA topoisomerase I [Providencia alcalifaciens].	24.38	320	198	10	77	386	292	577	1e-09	70.9
rs:WP_008612038	DNA topoisomerase I [Joostella marina].	28.52	263	148	10	77	334	249	476	1e-09	70.9
rs:WP_020712052	hypothetical protein [Acidobacteriaceae bacterium KBS 89].	21.58	468	279	15	34	450	227	657	1e-09	70.9
rs:WP_010320872	DNA topoisomerase I [Mycoplasma ovipneumoniae].	24.67	377	213	15	104	455	286	616	1e-09	70.5
tr:A0A084QFC0_9HYPO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFA62655.1};	24.10	307	188	8	37	335	283	552	1e-09	70.5
rs:WP_044250664	DNA topoisomerase I [Rhodopirellula sp. SWK7].	26.07	280	175	7	77	351	305	557	1e-09	70.9
rs:WP_027306991	DNA topoisomerase I [Candidatus Pelagibacter ubique].	24.43	442	269	16	43	454	226	632	1e-09	70.9
tr:K2EC32_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.52	310	181	9	86	378	264	537	1e-09	70.9
rs:WP_013695829	DNA topoisomerase I [Candidatus Pelagibacter sp. IMCC9063].	22.83	438	279	10	47	454	230	638	1e-09	70.9
tr:A0A024SJE7_HYPJE	SubName: Full=Prokaryotic type I DNA topoisomerase {ECO:0000313|EMBL:ETS05640.1};	24.32	296	189	7	40	334	258	519	1e-09	70.5
rs:WP_004736442	topoisomerase I [Vibrio splendidus].	25.65	382	228	15	77	446	290	627	1e-09	70.9
tr:K1TJK5_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EKC59411.1}; Flags: Fragment;	25.00	324	196	9	47	356	84	374	1e-09	69.7
sp:TOP3_SCHPO	RecName: Full=DNA topoisomerase 3; EC=5.99.1.2; AltName: Full=DNA topoisomerase III;	25.22	341	213	9	66	394	284	594	1e-09	70.5
rs:WP_044285592	DNA topoisomerase I [Mycoplasma ovipneumoniae].	26.06	376	215	14	101	455	283	616	1e-09	70.5
rs:WP_002983696	DNA topoisomerase I [Chryseobacterium gleum].	27.06	303	174	12	36	334	217	476	1e-09	70.9
rs:WP_041081072	DNA topoisomerase I [Thermotoga profunda].	24.76	319	185	11	74	377	244	522	1e-09	70.5
rs:WP_045127195	DNA topoisomerase I [Photobacterium angustum].	25.71	385	224	16	77	446	290	627	1e-09	70.9
rs:WP_027359053	DNA topoisomerase I [Desulforegula conservatrix].	22.80	421	268	14	47	449	225	606	1e-09	70.5
rs:WP_026821992	DNA topoisomerase I [Arsenophonus nasoniae].	25.07	347	199	10	35	356	221	531	1e-09	70.9
rs:WP_036979408	DNA topoisomerase I [Providencia alcalifaciens].	24.38	320	198	10	77	386	292	577	2e-09	70.9
rs:WP_013292672	DNA topoisomerase [Gallionella capsiferriformans].	23.98	342	180	12	73	399	281	557	2e-09	70.5
rs:WP_045921594	DNA topoisomerase I [Bifidobacterium coryneforme].	25.22	337	198	10	42	354	262	568	2e-09	70.9
rs:WP_023368568	DNA topoisomerase I [Mycobacterium kansasii].	25.93	378	232	11	41	399	274	622	2e-09	70.9
rs:WP_017095683	topoisomerase I [Vibrio splendidus].	25.65	382	228	15	77	446	290	627	2e-09	70.9
rs:WP_029202375	DNA topoisomerase I [Ornithinimicrobium pekingense].	26.11	337	192	10	77	384	291	599	2e-09	70.9
rs:WP_036795343	DNA topoisomerase I [Photobacterium phosphoreum].	26.46	325	180	14	42	354	258	535	2e-09	70.9
rs:WP_017085853	topoisomerase I [Vibrio splendidus].	25.65	382	228	15	77	446	290	627	2e-09	70.9
rs:WP_043234284	DNA topoisomerase I [Bosea sp. LC85].	24.72	449	259	17	45	454	228	636	2e-09	70.9
rs:WP_019174490	DNA topoisomerase I [Brevibacterium massiliense].	26.37	292	175	9	77	356	284	547	2e-09	70.9
rs:WP_005370813	topoisomerase I [Photobacterium angustum].	25.71	385	224	16	77	446	290	627	2e-09	70.9
rs:WP_033669627	DNA topoisomerase III, partial [Bacillus cereus].	33.93	112	72	2	36	147	244	353	2e-09	69.7
rs:WP_040278328	DNA topoisomerase I [Psychroserpens damuponensis].	26.45	276	169	7	61	334	233	476	2e-09	70.5
rs:XP_007688143	hypothetical protein COCMIDRAFT_95795 [Bipolaris oryzae ATCC 44560].	25.89	336	195	12	18	339	235	530	2e-09	70.5
rs:XP_004182129	hypothetical protein TBLA_0H03290 [Tetrapisispora blattae CBS 6284].	24.22	322	194	8	54	357	304	593	2e-09	70.5
rs:WP_019899838	DNA topoisomerase I [Methylotenera mobilis].	24.88	410	249	16	60	449	246	616	2e-09	70.5
rs:WP_045082622	MULTISPECIES: DNA topoisomerase I [Photobacterium].	25.71	385	224	16	77	446	290	627	2e-09	70.5
rs:WP_045149582	DNA topoisomerase I [Photobacterium angustum].	25.71	385	224	16	77	446	290	627	2e-09	70.5
rs:XP_011555583	PREDICTED: DNA topoisomerase 3-beta-1 [Plutella xylostella].	21.33	361	244	10	40	393	262	589	2e-09	70.5
rs:WP_010831330	DNA topoisomerase I [Nocardioides sp. CF8].	26.55	290	169	11	77	354	289	546	2e-09	70.5
rs:WP_047443649	DNA topoisomerase I [Chryseobacterium sp. YR005].	26.99	289	162	10	51	334	232	476	2e-09	70.5
rs:WP_017104280	topoisomerase I [Vibrio tasmaniensis].	25.65	382	228	15	77	446	290	627	2e-09	70.5
rs:WP_045041611	DNA topoisomerase I [Photobacterium kishitanii].	26.46	325	180	14	42	354	258	535	2e-09	70.5
rs:WP_024999384	DNA topoisomerase I [Prevotella falsenii].	25.00	268	159	7	77	334	252	487	2e-09	70.5
rs:WP_000054707	DNA topoisomerase I [Leptospira interrogans].	22.99	435	268	16	40	450	211	602	2e-09	70.5
rs:WP_006661696	DNA topoisomerase I subunit omega [Providencia alcalifaciens].	24.38	320	198	10	77	386	292	577	2e-09	70.5
tr:N1QMM7_SPHMS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.24	327	202	9	24	339	249	537	2e-09	70.5
tr:A0A0D9PTG7_METAN	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:KJK89383.1};	24.82	282	167	8	65	339	306	549	2e-09	70.5
rs:WP_036963747	DNA topoisomerase I [Providencia alcalifaciens].	24.38	320	198	10	77	386	292	577	2e-09	70.5
rs:WP_047806168	DNA topoisomerase I [Altererythrobacter marensis].	27.03	370	202	13	22	372	192	512	2e-09	70.5
rs:WP_039350538	DNA topoisomerase I [Mumia flava].	28.48	330	181	15	35	342	238	534	2e-09	70.5
rs:XP_006963403	DNA topoisomerase [Trichoderma reesei QM6a].	24.32	296	189	7	40	334	261	522	2e-09	70.5
rs:WP_036975684	DNA topoisomerase I [Providencia alcalifaciens].	24.38	320	198	10	77	386	292	577	2e-09	70.5
tr:R8S7W4_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.93	112	72	2	36	147	244	353	2e-09	69.7
rs:WP_028708795	DNA topoisomerase I [Propionicicella superfundia].	25.27	364	224	12	42	386	257	591	2e-09	70.5
rs:XP_002066263	GK18189 [Drosophila willistoni].	25.12	418	238	16	69	451	288	665	2e-09	70.9
rs:WP_046756567	DNA topoisomerase I [Kordia jejudonensis].	26.40	322	186	9	47	350	219	507	2e-09	70.5
rs:WP_012459087	DNA topoisomerase I [Sulfurihydrogenibium sp. YO3AOP1].	26.59	267	156	8	77	335	257	491	2e-09	70.5
rs:WP_047312482	DNA topoisomerase I [Dermacoccus sp. PE3].	26.18	340	206	11	31	354	239	549	2e-09	70.5
rs:WP_024817958	DNA topoisomerase I [Arthrobacter sp. 31Y].	25.52	290	176	10	77	354	289	550	2e-09	70.5
tr:A0A086JJZ8_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.54	346	229	9	39	377	260	573	2e-09	70.1
rs:WP_042743737	DNA topoisomerase III, partial [Staphylococcus aureus].	25.00	200	142	3	35	234	248	439	2e-09	69.7
rs:WP_027885936	DNA topoisomerase I [Mesonia mobilis].	25.86	290	159	10	65	340	238	485	2e-09	70.5
tr:X7ZAG8_MYCKA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.93	378	232	11	41	399	217	565	2e-09	70.5
rs:WP_017648987	hypothetical protein, partial [Streptococcus agalactiae].	27.08	192	127	4	59	245	263	446	2e-09	70.1
rs:WP_031872897	DNA topoisomerase III, partial [Staphylococcus aureus].	25.00	200	142	3	35	234	248	439	2e-09	69.7
tr:K1T7C4_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EKC62285.1}; Flags: Fragment;	26.86	175	105	4	166	338	18	171	2e-09	68.2
rs:WP_041222931	DNA topoisomerase I, partial [Deinococcus proteolyticus].	26.46	325	187	11	37	344	246	535	2e-09	70.5
rs:WP_012816677	DNA topoisomerase III [Staphylococcus aureus].	25.00	200	142	3	35	234	248	439	2e-09	69.7
rs:WP_039926969	DNA topoisomerase I [Leptospira vanthielii].	22.10	439	250	14	60	449	224	619	2e-09	70.1
rs:WP_044303446	DNA topoisomerase I [Rhodopirellula sallentina].	26.43	280	174	7	77	351	308	560	2e-09	70.5
tr:M5TW19_9PLAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.43	280	174	7	77	351	290	542	2e-09	70.5
rs:WP_029783752	DNA topoisomerase I, partial [Leptospira interrogans].	22.76	435	269	16	40	450	141	532	2e-09	70.1
tr:F8XS42_9GAMM	SubName: Full=DNA topoisomerase I, putative {ECO:0000313|EMBL:EGQ62535.1}; Flags: Fragment;	30.45	220	122	6	228	443	9	201	2e-09	68.9
rs:WP_035759241	DNA topoisomerase I [Granulicoccus phenolivorans].	25.00	352	204	10	35	356	244	565	2e-09	70.5
rs:XP_002184774	predicted protein, partial [Phaeodactylum tricornutum CCAP 1055/1].	25.33	304	180	10	47	334	248	520	2e-09	70.1
rs:WP_018280051	DNA topoisomerase I [Capnocytophaga cynodegmi].	25.44	283	173	9	56	334	228	476	2e-09	70.5
rs:WP_028277717	DNA topoisomerase I [Arthrobacter sp. I3].	26.69	326	196	11	77	385	289	588	2e-09	70.5
rs:WP_025700989	hypothetical protein, partial [Paenibacillus forsythiae].	38.10	84	52	0	38	121	233	316	2e-09	68.9
rs:XP_001785468	predicted protein [Physcomitrella patens].	23.37	415	263	12	39	434	256	634	2e-09	70.5
rs:WP_023846762	DNA topoisomerase I, partial [Porphyromonas gingivalis].	32.56	129	82	4	74	201	211	335	2e-09	69.3
rs:WP_045472181	DNA topoisomerase I [Winogradskyella sp. PG-2].	25.84	267	153	9	77	334	249	479	2e-09	70.5
rs:WP_017192797	hypothetical protein [Italian clover phyllody phytoplasma].	21.93	424	268	12	47	454	218	594	2e-09	70.1
tr:A0A0D1XG93_9PEZI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.12	333	208	9	18	339	235	530	2e-09	70.1
rs:WP_025492963	hypothetical protein, partial [Lachnospiraceae bacterium VE202-12].	37.96	108	62	1	278	385	12	114	2e-09	67.8
tr:X1ANN0_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_S02845 {ECO:0000313|EMBL:GAG84314.1}; Flags: Fragment;	24.24	297	190	7	166	452	21	292	2e-09	68.6
tr:A0A086PYJ7_TOXGO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.05	331	224	7	39	366	19	318	2e-09	69.3
rs:WP_034554136	DNA topoisomerase I [Capnocytophaga sp. oral taxon 335].	27.14	269	161	8	68	334	241	476	2e-09	70.5
tr:X8F2C5_MYCUL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.13	378	235	12	41	399	213	561	2e-09	70.1
tr:F0RMD4_DEIPM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.46	325	187	11	37	344	246	535	2e-09	70.5
rs:WP_044402915	DNA topoisomerase I [Lacinutrix sp. Hel_I_90].	26.18	275	166	8	77	346	249	491	2e-09	70.5
rs:WP_038254792	DNA topoisomerase I [Xenorhabdus bovienii].	25.64	390	236	17	77	452	282	631	2e-09	70.5
rs:XP_012832793	PREDICTED: uncharacterized protein LOC105953662 isoform X1 [Erythranthe guttatus].	23.73	434	267	13	61	458	590	995	2e-09	70.5
tr:X1HU06_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S12265 {ECO:0000313|EMBL:GAH73646.1};	27.78	216	123	6	165	377	21	206	2e-09	67.8
tr:N1W6Q6_9LEPT	SubName: Full=Putative DNA topoisomerase I {ECO:0000313|EMBL:EMY68927.1};	22.10	439	250	14	60	449	197	592	2e-09	70.1
rs:WP_028906033	DNA topoisomerase I [Prevotella intermedia].	25.37	268	158	7	77	334	252	487	2e-09	70.1
tr:M7CGR0_MORMO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EMP52879.1};	29.93	137	86	3	311	443	16	146	2e-09	67.4
tr:A0A0D2A416_9PEZI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.12	333	208	9	18	339	235	530	2e-09	70.1
rs:WP_034043528	DNA topoisomerase I [Flaviramulus ichthyoenteri].	25.71	280	166	8	61	334	233	476	2e-09	70.1
tr:U6KJS5_EIMTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.05	440	270	15	23	434	268	662	2e-09	70.5
tr:J1GV42_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.14	269	161	8	68	334	261	496	2e-09	70.1
rs:WP_020020763	hypothetical protein [alpha proteobacterium SCGC AAA160-J14].	25.71	424	248	17	60	452	241	628	2e-09	70.1
tr:A0A076ETH3_RHOOP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.69	327	201	10	41	354	269	566	2e-09	70.5
rs:WP_014679529	DNA topoisomerase I [Solitalea canadensis].	26.15	260	161	5	77	334	250	480	2e-09	70.1
rs:WP_040239086	DNA topoisomerase III, partial [Klebsiella pneumoniae].	29.22	154	89	5	315	459	13	155	2e-09	67.8
rs:WP_047231417	DNA topoisomerase I [Cellulosimicrobium funkei].	25.66	339	201	11	42	356	259	570	2e-09	70.5
rs:XP_002419382	DNA topoisomerase III, putative [Candida dubliniensis CD36].	26.47	340	197	12	56	378	275	578	2e-09	70.1
rs:WP_021770527	DNA topoisomerase I [Mitsuokella sp. oral taxon 131].	23.63	419	257	15	60	457	284	660	2e-09	70.1
rs:XP_009860760	PREDICTED: DNA topoisomerase 3-alpha [Ciona intestinalis].	24.77	323	196	10	40	353	269	553	2e-09	70.1
rs:XP_007712903	hypothetical protein COCCADRAFT_97731 [Bipolaris zeicola 26-R-13].	25.00	336	198	12	18	339	234	529	2e-09	70.1
rs:WP_008720593	Topoisomerase IA [Rhodococcus sp. AW25M09].	25.35	355	212	13	69	408	277	593	2e-09	70.1
rs:WP_045066573	DNA topoisomerase I [Rhodococcus sp. AD45].	24.62	329	202	10	41	354	266	563	2e-09	70.5
rs:WP_018986690	DNA topoisomerase I [Methylophilus methylotrophus].	24.58	419	241	16	60	449	246	618	2e-09	70.1
rs:WP_023926303	DNA topoisomerase I [Prevotella nigrescens].	25.75	268	157	7	77	334	252	487	2e-09	70.1
tr:X1L0J7_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_C01719 {ECO:0000313|EMBL:GAH99425.1}; Flags: Fragment;	26.34	262	132	8	227	450	4	242	2e-09	68.2
rs:WP_017191419	hypothetical protein [Poinsettia branch-inducing phytoplasma].	21.56	422	272	11	47	454	219	595	2e-09	70.1
rs:WP_006658706	topoisomerase I [Providencia alcalifaciens].	24.38	320	198	10	77	386	292	577	2e-09	70.1
rs:WP_007046121	DNA topoisomerase III [Subdoligranulum variabile].	34.87	152	77	5	298	445	8	141	2e-09	67.0
rs:WP_033235954	DNA topoisomerase I [Rhodococcus rhodochrous].	24.62	329	202	10	41	354	266	563	2e-09	70.1
rs:WP_007226908	topoisomerase I [marine gamma proteobacterium HTCC2143].	24.51	412	254	17	47	446	263	629	2e-09	70.1
rs:WP_018777017	MULTISPECIES: DNA topoisomerase I [Arthrobacter].	25.31	324	199	11	77	385	289	584	2e-09	70.1
rs:WP_041104016	DNA topoisomerase I [Burkholderia sp. 2385].	26.32	342	203	12	35	354	259	573	2e-09	70.1
rs:XP_006358794	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X2 [Solanum tuberosum].	24.39	287	184	8	66	351	223	477	2e-09	70.1
rs:WP_020023671	hypothetical protein [gamma proteobacterium SCGC AAA076-D02].	24.14	319	192	10	24	335	197	472	2e-09	70.1
tr:M1WBC5_CLAP2	SubName: Full=Related to DNA topoisomerase III {ECO:0000313|EMBL:CCE30983.1};	24.82	282	168	8	61	335	279	523	2e-09	70.1
rs:XP_012832794	PREDICTED: uncharacterized protein LOC105953662 isoform X2 [Erythranthe guttatus].	24.08	436	263	15	61	458	588	993	2e-09	70.5
tr:T0CZ37_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.17	173	106	4	20	186	29	187	2e-09	67.0
rs:WP_034740368	DNA topoisomerase I [Chryseobacterium vrystaatense].	25.91	301	180	10	36	334	217	476	2e-09	70.1
tr:A0A022RN26_ERYGU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.73	434	267	13	61	458	419	824	2e-09	70.1
rs:XP_011494373	PREDICTED: DNA topoisomerase 3-alpha [Ceratosolen solmsi marchali].	23.80	416	257	13	60	451	278	657	2e-09	70.1
tr:X1LNY1_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S04039 {ECO:0000313|EMBL:GAI21052.1}; Flags: Fragment;	25.84	267	160	8	190	452	1	233	2e-09	68.2
rs:WP_036888715	DNA topoisomerase I [Porphyromonas crevioricanis].	25.65	347	206	10	26	367	215	514	2e-09	70.1
rs:WP_036317285	DNA topoisomerase I [Micrococcus luteus].	26.32	342	203	12	35	354	259	573	2e-09	70.1
tr:F8DPI6_LACRS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.96	405	251	15	65	452	203	563	2e-09	70.1
rs:WP_035916355	DNA topoisomerase I [Knoellia sinensis].	26.14	394	226	14	38	397	239	601	2e-09	70.1
rs:WP_035263470	DNA topoisomerase I, partial [Desulfonatronum lacustre].	23.22	422	266	11	47	452	225	604	2e-09	70.1
tr:A0A0E0B044_9ORYZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.74	438	244	15	39	451	209	581	2e-09	70.1
rs:WP_000054710	DNA topoisomerase I [Leptospira interrogans].	22.76	435	269	16	40	450	211	602	2e-09	69.7
rs:WP_023625372	hypothetical protein, partial [Clostridium tyrobutyricum].	27.27	187	128	3	47	232	250	429	2e-09	69.3
rs:WP_038538797	DNA topoisomerase I [endosymbiont of Acanthamoeba sp. UWC8].	24.76	420	250	14	60	449	244	627	2e-09	70.1
rs:WP_045808600	DNA topoisomerase I [Candidatus Neoehrlichia lotoris].	22.86	433	274	13	47	452	232	631	2e-09	70.1
rs:NP_711902	DNA topoisomerase [Leptospira interrogans serovar Lai str. 56601].	22.76	435	269	16	40	450	211	602	2e-09	69.7
rs:WP_036341214	DNA topoisomerase I [Micrococcus luteus].	26.32	342	203	12	35	354	259	573	2e-09	70.1
rs:WP_044441756	DNA topoisomerase I [Agreia bicolorata].	27.81	302	160	13	77	354	292	559	2e-09	70.1
rs:WP_021738983	DNA topoisomerase, partial [Eubacterium ramulus].	30.72	153	100	3	43	193	218	366	2e-09	69.3
tr:A0A0A1SUL0_9HYPO	SubName: Full=Putative DNA topoisomerase 3 {ECO:0000313|EMBL:CEJ81921.1};	23.68	321	211	9	18	335	285	574	2e-09	70.1
rs:XP_009266901	DNA topoisomerase 3 [Wallemia ichthyophaga EXF-994].	25.86	321	194	9	40	352	265	549	2e-09	70.1
rs:WP_030161843	DNA topoisomerase I [Glycomyces sp. NRRL B-16210].	25.86	321	197	9	42	351	256	546	2e-09	70.1
rs:WP_047564485	DNA topoisomerase I [Mesorhizobium sp. F7].	24.85	338	201	9	42	356	252	559	2e-09	70.1
tr:K1TU90_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC73388.1};	28.83	163	109	4	34	193	7	165	2e-09	66.6
rs:WP_003853868	MULTISPECIES: topoisomerase I [Pantoea].	24.22	322	196	9	77	386	293	578	2e-09	70.1
rs:WP_013161892	DNA topoisomerase I [Propionibacterium freudenreichii].	23.52	421	253	14	41	431	254	635	2e-09	70.1
rs:WP_041572492	DNA topoisomerase I, partial [Candidatus Azobacteroides pseudotrichonymphae].	25.48	310	183	9	47	346	220	491	2e-09	70.1
tr:W8PPG8_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.86	321	197	9	42	351	252	542	2e-09	70.1
rs:XP_006358793	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X1 [Solanum tuberosum].	24.39	287	184	8	66	351	282	536	2e-09	70.1
tr:U2J849_PORGN	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERJ82416.1}; Flags: Fragment;	30.59	170	112	5	35	203	61	225	3e-09	67.0
rs:XP_004202802	Piso0_001663 [Millerozyma farinosa CBS 7064].	24.29	317	199	7	73	378	292	578	3e-09	69.7
tr:A0A086FA68_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.92	286	166	10	51	334	232	476	3e-09	70.1
rs:XP_008022021	hypothetical protein SETTUDRAFT_102706 [Setosphaeria turcica Et28A].	25.15	334	200	12	18	339	235	530	3e-09	69.7
rs:WP_010135732	DNA topoisomerase I [Flavobacteriaceae bacterium S85].	27.00	263	152	7	77	334	249	476	3e-09	70.1
rs:WP_010526611	DNA topoisomerase I [Thermophagus xiamenensis].	29.39	262	150	9	77	335	260	489	3e-09	70.1
rs:WP_013054252	DNA topoisomerase I [Mycoplasma crocodyli].	22.37	380	226	12	92	452	271	600	3e-09	69.7
rs:WP_018157186	DNA topoisomerase I [Demetria terragena].	25.42	354	218	10	42	377	250	575	3e-09	70.1
rs:XP_010326952	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Solanum lycopersicum].	23.88	289	183	9	66	351	223	477	3e-09	70.1
rs:WP_045035653	DNA topoisomerase I [Photobacterium iliopiscarium].	26.46	325	180	14	42	354	258	535	3e-09	70.1
tr:B6YQH0_AZOPC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.48	310	183	9	47	346	220	491	3e-09	69.7
tr:J6XYG5_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.67	163	107	3	57	216	133	292	3e-09	68.2
rs:WP_040999438	DNA topoisomerase I [Chryseobacterium oranimense].	25.91	301	180	10	36	334	217	476	3e-09	69.7
rs:WP_002131796	DNA topoisomerase I [Leptospira interrogans].	22.76	435	269	16	40	450	211	602	3e-09	69.7
tr:A0A0D4U5M3_YEASX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.82	368	200	12	42	380	296	619	3e-09	69.7
rs:WP_022414726	DNA topoisomerase [Clostridium sp. CAG:288].	23.44	448	288	15	18	449	187	595	3e-09	69.7
rs:WP_003670912	DNA topoisomerase I [Lactobacillus reuteri].	22.96	405	251	15	65	452	263	623	3e-09	69.7
rs:WP_006647016	topoisomerase I [Photobacterium sp. SKA34].	25.78	384	225	18	77	446	290	627	3e-09	69.7
gpu:CP009928_1108	DNA topoisomerase I [Chryseobacterium gallinarum]	26.92	286	166	10	51	334	232	476	3e-09	69.7
rs:WP_042958068	DNA topoisomerase, partial [Enterococcus faecium].	30.67	163	107	3	57	216	124	283	3e-09	67.8
rs:XP_003578369	PREDICTED: DNA topoisomerase 3-beta [Brachypodium distachyon].	22.77	382	229	14	65	425	284	620	3e-09	69.7
rs:XP_567296	DNA topoisomerase type I [Cryptococcus neoformans var. neoformans JEC21].	25.55	321	191	11	41	354	266	545	3e-09	69.7
rs:WP_022918380	DNA topoisomerase I [Ruania albidiflava].	25.99	327	202	9	42	356	255	553	3e-09	69.7
rs:XP_007801474	hypothetical protein EPUS_08478 [Endocarpon pusillum Z07020].	24.84	322	192	9	73	377	294	582	3e-09	69.7
rs:WP_015114554	DNA topoisomerase I [Nostoc sp. PCC 7107].	22.57	421	271	12	40	445	241	621	3e-09	69.7
rs:WP_039692301	hypothetical protein, partial [Streptococcus gallolyticus].	27.57	185	113	5	167	339	33	208	3e-09	66.6
tr:L2TJV5_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.69	327	201	10	41	354	247	544	3e-09	69.7
rs:WP_000054708	DNA topoisomerase I [Leptospira interrogans].	22.76	435	269	16	40	450	211	602	3e-09	69.7
rs:XP_004248022	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Solanum lycopersicum].	23.88	289	183	9	66	351	282	536	3e-09	69.7
rs:WP_036476290	DNA topoisomerase I [Nesterenkonia sp. AN1].	25.76	361	217	12	37	376	256	586	3e-09	69.7
rs:WP_037203507	MULTISPECIES: DNA topoisomerase I [Rhodococcus].	25.69	327	201	10	41	354	269	566	3e-09	69.7
rs:WP_026809853	DNA topoisomerase I [Arenibacter latericius].	25.76	295	159	9	56	334	228	478	3e-09	69.7
rs:WP_018761827	DNA topoisomerase I [Arthrobacter sp. 135MFCol5.1].	25.86	290	175	10	77	354	289	550	3e-09	69.7
tr:X1DAB2_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_S08380 {ECO:0000313|EMBL:GAG93366.1}; Flags: Fragment;	28.25	177	103	4	210	380	7	165	3e-09	66.2
rs:WP_006996844	DNA topoisomerase I [Candidatus Pelagibacter ubique].	24.43	442	269	16	43	454	226	632	3e-09	69.7
rs:WP_041876214	DNA topoisomerase I [Bdellovibrio sp. ArHS].	25.46	271	173	6	77	344	294	538	3e-09	69.7
rs:WP_007298531	DNA topoisomerase I [Rhodococcus imtechensis].	25.69	327	201	10	41	354	269	566	3e-09	69.7
rs:WP_010679545	DNA topoisomerase I [Leptospira interrogans].	22.76	435	269	16	40	450	211	602	3e-09	69.3
rs:XP_010338329	PREDICTED: DNA topoisomerase 3-alpha [Saimiri boliviensis boliviensis].	26.16	279	175	8	40	309	289	545	3e-09	69.7
rs:WP_028849756	DNA topoisomerase I [Thermocrispum municipale].	25.69	327	203	10	40	354	260	558	3e-09	69.7
rs:WP_037228878	DNA topoisomerase I [Rhodococcus wratislaviensis].	25.69	327	201	10	41	354	269	566	3e-09	69.7
rs:WP_000054711	DNA topoisomerase I [Leptospira interrogans].	22.76	435	269	16	40	450	211	602	3e-09	69.3
rs:WP_034570232	hypothetical protein [Helicobacter sanguini].	21.62	444	260	15	26	439	217	602	3e-09	69.3
rs:WP_034545244	DNA topoisomerase I [Clostridiales bacterium S7-1-4].	25.77	388	224	13	86	454	267	609	3e-09	69.7
rs:WP_005248447	DNA topoisomerase I [Rhodococcus opacus].	25.69	327	201	10	41	354	269	566	3e-09	69.7
rs:WP_018108870	DNA topoisomerase I [Bacteroides propionicifaciens].	25.67	300	186	9	40	334	217	484	3e-09	69.7
tr:T0KH08_COLGC	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EQB54737.1};	25.32	308	185	11	37	336	254	524	3e-09	69.3
rs:WP_043483740	DNA topoisomerase I [Arthrobacter sp. SPG23].	25.86	290	175	10	77	354	292	553	3e-09	69.7
rs:WP_024800961	DNA topoisomerase I [Nocardia sp. BMG51109].	23.64	330	207	10	41	354	274	574	3e-09	69.7
rs:WP_038556453	DNA topoisomerase I [Synechococcus sp. KORDI-52].	25.99	354	222	11	26	370	233	555	3e-09	69.7
rs:WP_044283986	DNA topoisomerase I [Mycoplasma ovipneumoniae].	25.47	373	215	12	104	455	286	616	3e-09	69.3
tr:K1TSP6_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC62381.1}; Flags: Fragment;	32.73	110	70	3	65	174	2	107	3e-09	65.9
tr:A0A060XW94_ONCMY	SubName: Full=Oncorhynchus mykiss genomic scaffold, scaffold_1973 {ECO:0000313|EMBL:CDQ83751.1};	25.10	263	157	7	174	424	1	235	3e-09	67.4
rs:WP_030151791	DNA topoisomerase I [Oerskovia turbata].	24.72	352	201	11	42	356	261	585	3e-09	69.7
rs:WP_003723893	DNA topoisomerase I, partial [Listeria monocytogenes].	24.56	285	177	10	29	294	205	470	3e-09	68.9
tr:A0A010PCK1_9MICC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.76	361	217	12	37	376	250	580	3e-09	69.7
rs:WP_015732803	DNA topoisomerase I [Methanocaldococcus vulcanius].	23.00	287	187	8	18	294	216	478	3e-09	69.7
rs:WP_044106603	DNA topoisomerase I [cyanobacterium endosymbiont of Epithemia turgida].	23.82	340	226	8	37	370	243	555	3e-09	69.7
rs:WP_008986675	topoisomerase I [Photobacterium leiognathi].	25.71	385	224	17	77	446	292	629	3e-09	69.7
rs:WP_048500850	DNA topoisomerase I [Chryseobacterium sp. BLS98].	25.91	301	180	10	36	334	217	476	3e-09	69.7
rs:WP_024148479	hypothetical protein, partial [Salmonella enterica].	26.85	257	157	7	193	446	1	229	3e-09	68.9
rs:WP_002353593	DNA topoisomerase, partial [Enterococcus faecium].	30.67	163	107	3	57	216	268	427	3e-09	68.9
rs:WP_029815476	DNA topoisomerase III, partial [Yersinia pestis].	37.11	97	61	0	304	400	1	97	3e-09	65.5
rs:WP_029285403	DNA topoisomerase I [Pedobacter sp. R20-19].	25.17	302	185	7	36	335	219	481	3e-09	69.7
rs:WP_000054709	DNA topoisomerase I [Leptospira interrogans].	22.76	435	269	16	40	450	211	602	3e-09	69.3
rs:WP_002105176	DNA topoisomerase I [Leptospira interrogans].	22.76	435	269	16	40	450	211	602	3e-09	69.3
tr:F3GEZ0_PSESJ	SubName: Full=Orf50 {ECO:0000313|EMBL:EGH45640.1}; Flags: Fragment;	35.58	104	67	0	33	136	240	343	3e-09	68.6
tr:A0A0D4V7D1_YEASX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.54	368	201	12	42	380	296	619	4e-09	69.3
rs:WP_035315918	hypothetical protein, partial [Brochothrix campestris].	30.15	136	89	2	113	248	1	130	4e-09	65.5
rs:WP_044636391	DNA topoisomerase I [Propionibacterium freudenreichii].	23.47	409	245	13	41	419	254	624	4e-09	69.7
tr:U4U7I5_DENPD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.72	373	251	10	22	385	197	537	4e-09	69.3
tr:A0A067NTL6_PLEOS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.20	271	151	10	97	357	309	540	4e-09	69.3
rs:XP_008337494	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Malus domestica].	22.62	389	242	14	65	434	284	632	4e-09	69.3
rs:WP_036858196	hypothetical protein, partial [Prevotella amnii].	30.00	130	78	3	74	203	75	191	4e-09	66.6
rs:WP_035325402	DNA topoisomerase I [Dokdonia donghaensis].	26.69	326	176	11	26	340	212	485	4e-09	69.3
rs:XP_008337495	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Malus domestica].	22.62	389	242	14	65	434	224	572	4e-09	69.3
rs:WP_000054706	DNA topoisomerase I [Leptospira interrogans].	22.76	435	269	16	40	450	211	602	4e-09	69.3
rs:WP_032485350	DNA topoisomerase III, partial [Yersinia pestis].	37.11	97	61	0	304	400	2	98	4e-09	65.5
rs:WP_022925447	DNA topoisomerase I [Serinicoccus marinus].	25.88	371	204	14	44	384	265	594	4e-09	69.3
rs:XP_003682560	hypothetical protein TDEL_0F05380 [Torulaspora delbrueckii].	23.97	388	240	10	39	401	278	635	4e-09	69.3
rs:WP_008867038	DNA topoisomerase I [Flavobacteria bacterium MS024-3C].	25.34	296	188	7	41	334	213	477	4e-09	69.3
rs:WP_024838933	DNA topoisomerase I [Cellulosimicrobium cellulans].	25.44	338	202	11	42	356	259	569	4e-09	69.3
rs:XP_007275049	DNA topoisomerase [Colletotrichum gloeosporioides Nara gc5].	25.32	308	185	11	37	336	254	524	4e-09	69.3
rs:WP_032392025	topoisomerase I [Rhodococcus fascians].	26.51	332	183	13	79	402	284	562	4e-09	69.3
rs:WP_027494171	topoisomerase I [Rhodococcus sp. JG-3].	26.57	335	179	15	79	402	284	562	4e-09	69.3
rs:WP_020028714	hypothetical protein [gamma proteobacterium SCGC AAA076-F14].	22.86	315	197	8	25	335	200	472	4e-09	69.3
rs:XP_003033227	hypothetical protein SCHCODRAFT_54192 [Schizophyllum commune H4-8].	26.15	371	209	12	39	385	256	585	4e-09	68.9
rs:WP_018414164	DNA topoisomerase I [Candidatus Pelagibacter ubique].	24.43	442	269	16	43	454	226	632	4e-09	69.3
rs:XP_009414693	PREDICTED: DNA topoisomerase 3-beta isoform X3 [Musa acuminata subsp. malaccensis].	22.92	349	207	14	65	393	204	510	4e-09	69.3
tr:W6KJC0_9TRYP	SubName: Full=Genomic scaffold, scaffold_8 {ECO:0000313|EMBL:CCW62315.1};	22.91	358	230	11	39	386	252	573	4e-09	69.3
rs:WP_021910210	DNA topoisomerase I [Prevotella sp. CAG:755].	22.96	318	197	6	39	346	214	493	4e-09	69.3
rs:WP_018477788	DNA topoisomerase I [Pontibacter roseus].	24.83	294	182	7	47	334	218	478	4e-09	69.3
rs:WP_041844049	DNA topoisomerase I [Thermotoga sp. RQ7].	26.91	327	182	12	69	377	236	523	4e-09	68.9
rs:WP_020026414	hypothetical protein [gamma proteobacterium SCGC AAA076-D13].	23.42	316	194	9	25	335	200	472	4e-09	69.3
rs:XP_011780170	DNA topoisomerase III, putative [Trypanosoma brucei gambiense DAL972].	22.22	414	273	12	37	434	250	630	4e-09	69.3
rs:WP_037319125	DNA topoisomerase I [Ruminobacter sp. RM87].	24.56	281	166	6	80	354	285	525	4e-09	69.3
tr:I1BYY5_RHIO9	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.35	394	231	14	75	453	253	590	4e-09	69.3
rs:WP_034073736	hypothetical protein, partial [Pseudomonas aeruginosa].	25.13	394	218	17	77	446	245	585	4e-09	68.9
rs:XP_003738127	PREDICTED: DNA topoisomerase 3-beta-1-like [Metaseiulus occidentalis].	23.08	364	221	12	38	385	259	579	4e-09	69.3
rs:WP_044126130	hypothetical protein [Vibrio cholerae].	25.17	294	176	9	70	354	262	520	4e-09	69.3
rs:WP_011693180	DNA topoisomerase I [Arthrobacter sp. FB24].	25.86	290	175	10	77	354	292	553	4e-09	69.3
rs:WP_043119530	DNA topoisomerase I [Sinomonas sp. MUSC 117].	23.87	331	210	10	41	354	262	567	4e-09	69.3
rs:XP_009371100	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Pyrus x bretschneideri].	22.62	389	242	14	65	434	224	572	4e-09	69.3
rs:WP_004380549	DNA topoisomerase I [Prevotella oulorum].	24.05	291	188	7	47	334	222	482	4e-09	69.3
tr:M0TVE7_MUSAM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.92	349	207	14	65	393	258	564	4e-09	69.3
rs:WP_025867914	DNA topoisomerase I, partial [Bacteroides nordii].	35.61	132	78	5	60	190	263	388	4e-09	68.6
rs:WP_005747022	DNA topoisomerase III, partial [Pseudomonas amygdali].	32.82	131	79	2	322	452	1	122	4e-09	65.5
rs:WP_033363230	DNA topoisomerase I [Dactylosporangium aurantiacum].	24.79	363	221	13	42	385	258	587	4e-09	69.3
rs:WP_020169475	DNA topoisomerase I [Candidatus Pelagibacter ubique].	24.43	442	269	16	43	454	226	632	4e-09	69.3
rs:WP_015918923	DNA topoisomerase I [Thermotoga neapolitana].	26.91	327	182	12	69	377	236	523	4e-09	68.9
rs:XP_005536404	DNA topoisomerase I [Cyanidioschyzon merolae strain 10D].	28.15	341	194	15	25	338	382	698	5e-09	69.3
rs:WP_019530187	topoisomerase I [Dasania marina].	23.19	414	255	13	48	446	264	629	5e-09	69.3
tr:E4YMV5_OIKDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.92	317	192	11	90	398	305	583	5e-09	69.3
rs:WP_019879161	hypothetical protein [Succinispira mobilis].	23.13	441	272	18	36	454	215	610	5e-09	68.9
rs:WP_022724748	DNA topoisomerase I [alpha proteobacterium SCGC AAA536-K22].	26.87	428	228	21	65	452	246	628	5e-09	69.3
rs:XP_009217839	DNA topoisomerase III [Gaeumannomyces graminis var. tritici R3-111a-1].	23.78	307	188	8	37	333	255	525	5e-09	68.9
rs:WP_026631521	DNA topoisomerase I [Dyadobacter alkalitolerans].	27.27	275	166	10	68	340	242	484	5e-09	69.3
rs:WP_019039527	DNA topoisomerase I [Psychroflexus tropicus].	25.00	276	164	7	65	334	238	476	5e-09	69.3
rs:XP_009371098	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Pyrus x bretschneideri].	22.62	389	242	14	65	434	284	632	5e-09	69.3
rs:WP_023502268	Topoisomerase IA [uncultured archaeon A07HN63].	25.74	338	203	12	31	345	243	555	5e-09	69.3
rs:WP_003526249	hypothetical protein, partial [[Clostridium] clostridioforme].	31.21	141	92	3	34	173	221	357	5e-09	68.2
tr:A0A0D4UDT0_YEASX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.54	368	201	12	42	380	296	619	5e-09	68.9
rs:WP_037369212	DNA topoisomerase I [Amycolatopsis orientalis].	24.93	341	201	11	35	351	255	564	5e-09	69.3
tr:U6MZY6_9EIME	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.76	435	260	17	30	434	88	476	5e-09	68.9
rs:WP_021778244	DNA topoisomerase I [Dokdonia sp. MED134].	26.90	290	162	10	62	340	235	485	5e-09	68.9
rs:XP_009414691	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Musa acuminata subsp. malaccensis].	22.92	349	207	14	65	393	284	590	5e-09	68.9
tr:G6DFU9_DANPL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.39	402	258	14	40	424	262	626	5e-09	68.9
rs:WP_006704667	topoisomerase I [Candidatus Regiella insecticola].	24.92	321	197	9	77	387	293	579	5e-09	68.9
rs:WP_020774334	DNA topoisomerase I [Leptospira alstonii].	21.93	415	253	14	61	450	233	601	5e-09	68.9
tr:E4YXQ0_OIKDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.92	317	192	11	90	398	305	583	5e-09	68.9
rs:WP_015407025	DNA topoisomerase I [Dehalococcoides mccartyi].	21.33	483	283	13	33	450	211	661	5e-09	68.9
rs:WP_009644006	toprim domain protein, partial [Mogibacterium sp. CM50].	29.94	157	86	4	47	192	235	378	5e-09	68.2
rs:WP_011928996	DNA topoisomerase I [Dehalococcoides mccartyi].	21.33	483	283	13	33	450	211	661	5e-09	68.9
rs:XP_009414692	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Musa acuminata subsp. malaccensis].	22.92	349	207	14	65	393	279	585	5e-09	68.9
tr:A0A0D4TTY4_YEASX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.54	368	201	12	42	380	296	619	5e-09	68.9
rs:WP_041495996	DNA topoisomerase I [Nonlabens marinus].	24.40	336	211	10	65	377	238	553	5e-09	68.9
tr:A0A0E0NQ38_ORYRU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.64	440	245	16	39	452	270	644	5e-09	68.9
rs:WP_007163929	DNA topoisomerase I [Erythrobacter sp. NAP1].	23.26	387	234	11	1	371	171	510	5e-09	68.9
rs:WP_027120797	DNA topoisomerase I [Mycoplasma lipofaciens].	23.92	418	200	17	79	452	253	596	5e-09	68.6
rs:WP_004278075	DNA topoisomerase I [Campylobacter upsaliensis].	24.81	399	228	18	74	450	252	600	5e-09	68.9
rs:WP_028950752	DNA topoisomerase I [Sulfurihydrogenibium subterraneum].	24.67	381	227	13	19	385	202	536	5e-09	68.9
rs:XP_007873141	hypothetical protein PNEG_01223 [Pneumocystis murina B123].	22.95	353	216	10	70	400	286	604	5e-09	68.6
rs:WP_040248414	DNA topoisomerase I [Psychroserpens mesophilus].	25.99	277	169	8	61	334	233	476	5e-09	68.9
rs:WP_008629835	DNA topoisomerase I [Mariniradius saccharolyticus].	25.54	278	176	8	65	340	237	485	5e-09	68.9
rs:WP_035567454	DNA topoisomerase I [Hymenobacter sp. IS2118].	26.01	296	182	6	47	334	219	485	5e-09	68.9
rs:WP_021482010	hypothetical protein, partial [Bacillus sp. EGD-AK10].	26.64	304	172	11	77	356	33	309	5e-09	68.9
rs:WP_000054712	DNA topoisomerase I [Leptospira interrogans].	22.76	435	269	16	40	450	211	602	5e-09	68.6
rs:WP_042159536	hypothetical protein, partial [Pseudomonas aeruginosa].	25.13	394	218	17	77	446	245	585	5e-09	68.6
tr:K1T7K2_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC62380.1};	41.84	98	52	1	275	372	72	164	5e-09	65.5
rs:XP_006682765	hypothetical protein BATDEDRAFT_14853, partial [Batrachochytrium dendrobatidis JAM81].	25.07	355	211	14	37	377	245	558	5e-09	68.6
rs:WP_006838846	DNA topoisomerase I, partial [Bacillus sp. SG-1].	23.84	302	182	10	50	336	227	495	5e-09	68.6
rs:WP_010521566	DNA topoisomerase I [Flavobacteriaceae bacterium HQM9].	24.32	292	187	7	45	334	217	476	5e-09	68.9
tr:A0A084RTP3_STACH	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFA79578.1};	24.43	307	187	9	37	335	283	552	5e-09	68.9
rs:WP_035879967	DNA topoisomerase I, partial [Cryobacterium sp. MLB-32].	26.07	349	204	12	57	379	269	589	5e-09	68.9
rs:WP_021030004	DNA topoisomerase I [Segniliparus rugosus].	27.12	295	168	10	77	354	309	573	5e-09	68.9
rs:WP_016443329	DNA topoisomerase I [Actinotignum schaalii].	25.00	372	219	14	40	387	248	583	5e-09	68.9
tr:E4XGA0_OIKDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.92	317	192	11	90	398	305	583	6e-09	68.9
rs:WP_012473240	DNA topoisomerase I [Candidatus Amoebophilus asiaticus].	26.86	283	171	7	65	340	238	491	6e-09	68.9
rs:WP_035903648	DNA topoisomerase I [Knoellia subterranea].	25.22	341	203	10	38	356	244	554	6e-09	68.9
rs:WP_023940314	DNA topoisomerase I [Porphyromonas crevioricanis].	25.65	347	206	10	26	367	215	514	6e-09	68.9
gp:CP009967_5	DNA topoisomerase family protein [Bacillus cereus E33L]	25.45	224	156	6	65	281	2	221	6e-09	65.9
rs:WP_026979520	DNA topoisomerase I [Flavobacterium suncheonense].	25.87	344	197	11	77	400	249	554	6e-09	68.9
rs:WP_006910134	DNA topoisomerase I [Cyanobium sp. PCC 7001].	24.07	378	250	9	26	395	237	585	6e-09	68.9
rs:WP_017193621	hypothetical protein [Vaccinium witches'-broom phytoplasma].	21.93	424	268	12	47	454	218	594	6e-09	68.6
tr:A0A090M2L9_OSTTA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.96	379	242	11	40	404	262	604	6e-09	68.9
rs:WP_011309190	DNA topoisomerase I [Dehalococcoides mccartyi].	21.33	483	283	13	33	450	211	661	6e-09	68.6
tr:F9WNV5_TRYVY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.90	310	205	6	44	350	208	486	6e-09	68.6
rs:WP_033494912	DNA topoisomerase I [Bifidobacterium psychraerophilum].	25.89	336	196	12	42	354	261	566	6e-09	68.9
rs:WP_000112700	DNA topoisomerase I, partial [Leptospira interrogans].	22.81	399	242	15	74	449	28	383	6e-09	67.8
rs:WP_026775681	DNA topoisomerase I [Polaribacter sp. Hel_I_88].	26.26	278	169	7	60	334	232	476	6e-09	68.9
tr:A0A0B7F0W9_THACB	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CEL51686.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEL51686.1};	25.87	317	174	12	98	393	299	575	6e-09	68.9
rs:WP_017793097	DNA topoisomerase I [Leucobacter salsicius].	26.26	297	168	11	77	354	291	555	6e-09	68.9
rs:XP_011402446	PREDICTED: DNA topoisomerase 3-beta-1-like, partial [Amphimedon queenslandica].	20.77	366	223	12	59	400	280	602	6e-09	68.9
tr:A0A0E0ILY8_ORYNI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.40	366	230	13	44	393	1407	1734	6e-09	68.9
tr:W7LY95_GIBM7	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EWG44273.1};	25.00	284	169	7	59	335	277	523	6e-09	68.6
rs:WP_044638043	DNA topoisomerase I [Siansivirga zeaxanthinifaciens].	26.52	264	152	8	77	334	249	476	6e-09	68.9
rs:WP_007184766	DNA topoisomerase I [Hydrocarboniphaga effusa].	26.57	350	210	12	50	380	238	559	6e-09	68.9
rs:WP_015388986	DNA topoisomerase III [Photobacterium damselae].	29.61	152	91	5	315	459	31	173	6e-09	66.2
tr:A0A0D4TPT2_YEASX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.54	368	201	12	42	380	296	619	6e-09	68.6
rs:WP_023937657	DNA topoisomerase I [Porphyromonas crevioricanis].	25.65	347	206	10	26	367	215	514	6e-09	68.6
tr:M6CI84_LEPME	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EMJ85945.1};	23.89	314	176	11	61	354	143	413	6e-09	68.6
rs:WP_033491154	DNA topoisomerase I [Bifidobacterium indicum].	25.52	337	197	11	42	354	262	568	6e-09	68.9
rs:XP_002289424	topoisomerase, partial [Thalassiosira pseudonana CCMP1335].	23.67	300	193	8	40	333	283	552	6e-09	68.6
tr:K1S8S4_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC51824.1}; Flags: Fragment;	38.55	83	50	1	257	339	7	88	6e-09	63.9
tr:J1RFB0_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.38	327	202	10	41	354	247	544	6e-09	68.9
rs:WP_031633366	hypothetical protein, partial [Pseudomonas aeruginosa].	25.38	394	217	18	77	446	245	585	6e-09	68.6
rs:WP_034709441	DNA topoisomerase I [Chryseobacterium soli].	26.32	304	175	11	36	334	217	476	6e-09	68.6
tr:V2BC43_SALDE	SubName: Full=DNA topoisomerase I subunit omega {ECO:0000313|EMBL:ESH20253.1}; EC=5.99.1.2 {ECO:0000313|EMBL:ESH20253.1};	27.05	244	147	7	206	446	14	229	6e-09	68.2
rs:XP_007913893	putative dna topoisomerase iii protein [Togninia minima UCRPA7].	25.08	303	182	9	40	334	193	458	6e-09	68.6
rs:WP_034800380	DNA topoisomerase I [Intrasporangium oryzae].	25.38	331	203	9	42	356	257	559	6e-09	68.9
tr:A0A0C2D6T5_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.75	421	252	17	65	459	438	815	6e-09	68.9
rs:WP_013170872	DNA topoisomerase I [Arcanobacterium haemolyticum].	27.11	343	195	14	77	396	286	596	6e-09	68.9
rs:WP_035983940	DNA topoisomerase I [Leptospira meyeri].	23.89	314	176	11	61	354	225	495	6e-09	68.6
tr:I0II60_PHYMF	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.75	400	224	17	77	446	332	684	6e-09	68.9
rs:WP_000054703	DNA topoisomerase I [Leptospira interrogans].	22.76	435	269	16	40	450	211	602	6e-09	68.6
tr:A0A0E0B4W4_9ORYZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.61	345	213	13	65	393	1420	1726	6e-09	68.9
tr:X0SS58_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_C00478 {ECO:0000313|EMBL:GAF77951.1}; Flags: Fragment;	25.78	287	164	9	179	456	2	248	7e-09	67.4
rs:WP_012691439	DNA topoisomerase I [Rhodococcus opacus].	25.38	327	202	10	41	354	269	566	7e-09	68.6
tr:G5JLM3_9STAP	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EHJ06903.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EHJ06903.1};	25.49	204	116	7	166	358	47	225	7e-09	66.2
rs:WP_016884539	DNA topoisomerase I [Rhodococcus sp. DK17].	25.38	327	202	10	41	354	269	566	7e-09	68.6
rs:WP_034019142	hypothetical protein, partial [Pseudomonas aeruginosa].	25.13	394	218	17	77	446	245	585	7e-09	68.6
rs:XP_002495860	ZYRO0C04642p [Zygosaccharomyces rouxii].	24.30	321	190	10	56	357	298	584	7e-09	68.6
rs:XP_003844019	hypothetical protein LEMA_P016700.1 [Leptosphaeria maculans JN3].	27.95	254	139	7	93	339	314	530	7e-09	68.6
rs:WP_026544435	DNA topoisomerase I [Arthrobacter sp. 35/47].	25.17	298	177	10	77	356	296	565	7e-09	68.6
rs:WP_032386860	topoisomerase I [Rhodococcus fascians].	25.35	355	212	13	69	408	277	593	7e-09	68.6
rs:WP_027122172	DNA topoisomerase I [Mycoplasma imitans].	22.88	437	233	16	86	452	300	702	7e-09	68.6
rs:WP_021911928	DNA topoisomerase [Eubacterium sp. CAG:786].	28.28	244	136	9	217	452	8	220	7e-09	67.0
tr:A0A0D4V1D3_YEASX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.54	368	201	12	42	380	296	619	7e-09	68.6
rs:WP_011596786	MULTISPECIES: DNA topoisomerase I [Rhodococcus].	25.38	327	202	10	41	354	269	566	7e-09	68.6
rs:XP_012768266	DNA topoisomerase, putative [Babesia bigemina].	24.93	365	216	13	37	379	260	588	7e-09	68.6
rs:WP_007293494	DNA topoisomerase, partial [delta proteobacterium MLMS-1].	28.00	200	116	7	257	452	18	193	7e-09	67.4
rs:WP_025069710	DNA topoisomerase I [Prevotella oulorum].	24.05	291	188	7	47	334	222	482	7e-09	68.6
rs:WP_036156769	DNA topoisomerase I [Maribacter forsetii].	25.77	291	182	8	47	334	219	478	7e-09	68.6
rs:WP_038041729	hypothetical protein, partial [Thermodesulfobacterium hveragerdense].	26.39	269	152	9	86	348	266	494	7e-09	68.2
tr:A0A0D9Z2H3_9ORYZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.64	440	245	16	39	452	222	596	7e-09	68.6
tr:A0A084Q054_STACH	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFA55839.1};	24.10	307	188	9	37	335	254	523	7e-09	68.2
tr:R9XJX5_ASHAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.03	222	127	4	166	378	397	592	7e-09	68.2
tr:A0A074XR39_AURPU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.28	274	159	6	73	339	302	539	7e-09	68.2
rs:WP_031502913	DNA topoisomerase I [Pseudothermotoga hypogea].	23.27	391	239	13	38	409	205	553	8e-09	68.6
tr:G9N9J3_HYPVG	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHK16612.1};	23.51	302	184	8	40	334	258	519	8e-09	68.2
tr:M6W5P2_LEPBO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.08	299	182	10	166	450	70	334	8e-09	67.4
tr:K5BPD2_LEPME	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EKJ85502.1};	23.89	314	176	11	61	354	137	407	8e-09	68.2
rs:WP_044002451	DNA topoisomerase I [Hymenobacter swuensis].	29.93	294	171	11	47	334	220	484	8e-09	68.6
rs:XP_008651687	PREDICTED: uncharacterized protein LOC100383032 isoform X1 [Zea mays].	22.25	382	231	14	65	425	163	499	8e-09	68.6
tr:F9WNR1_TRYVY	SubName: Full=DNA topoisomerase, putative {ECO:0000313|EMBL:CCD19182.1};	23.75	320	208	5	66	379	231	520	8e-09	68.6
tr:R0AG44_CLOBU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ENZ31102.1};	34.06	138	81	3	311	445	6	136	8e-09	65.5
rs:WP_033627137	DNA topoisomerase, partial [Enterococcus faecium].	31.45	159	103	3	57	212	237	392	8e-09	67.8
rs:XP_010432895	PREDICTED: uncharacterized protein LOC104717073 [Camelina sativa].	23.52	438	264	14	61	458	730	1136	8e-09	68.6
rs:WP_028265367	DNA topoisomerase I [Arthrobacter sp. MA-N2].	25.17	290	177	10	77	354	289	550	8e-09	68.6
rs:WP_002347691	hypothetical protein, partial [Enterococcus faecium].	31.45	159	103	3	57	212	230	385	8e-09	67.4
rs:WP_044356048	DNA topoisomerase III, partial [Paenibacillus sp. E194].	35.96	89	56	1	34	121	229	317	8e-09	67.0
rs:WP_036956550	DNA topoisomerase I [Providencia alcalifaciens].	24.38	320	198	10	77	386	292	577	8e-09	68.6
rs:WP_020021509	hypothetical protein [alpha proteobacterium SCGC AAA536-G10].	25.06	423	229	19	71	452	253	628	8e-09	68.6
rs:WP_043658560	DNA topoisomerase I [Cellulosimicrobium cellulans].	26.64	304	172	11	77	356	294	570	8e-09	68.6
rs:WP_034869972	DNA topoisomerase I [Elizabethkingia miricola].	27.02	322	187	10	36	350	217	497	8e-09	68.6
rs:WP_026919797	DNA topoisomerase I [Gordonia shandongensis].	26.06	330	200	13	66	379	289	590	8e-09	68.6
rs:WP_033523275	DNA topoisomerase I [Bifidobacterium merycicum].	26.97	330	195	12	40	354	256	554	8e-09	68.6
rs:WP_025229321	hypothetical protein [Fimbriimonas ginsengisoli].	25.77	326	190	10	41	344	254	549	8e-09	68.6
rs:WP_011741856	DNA topoisomerase I [Mycobacterium ulcerans].	25.13	378	235	12	41	399	274	622	8e-09	68.6
rs:WP_036458469	DNA topoisomerase I, partial [Mycoplasma iners].	24.74	384	214	14	92	452	270	601	8e-09	68.2
tr:A6NXR7_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EDM99087.1};	34.87	152	77	5	298	445	8	141	8e-09	65.5
rs:WP_036788982	DNA topoisomerase I [Porphyromonas canoris].	26.74	258	146	7	86	334	258	481	8e-09	68.2
tr:A0A0D4TSX7_YEASX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.59	340	185	11	42	357	296	591	8e-09	68.2
tr:X1HFT9_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S10476 {ECO:0000313|EMBL:GAH68292.1}; Flags: Fragment;	26.27	255	129	13	221	453	8	225	8e-09	66.2
rs:XP_001526340	conserved hypothetical protein [Lodderomyces elongisporus NRRL YB-4239].	26.17	321	194	10	46	357	263	549	8e-09	68.2
tr:A0A0E0QTB8_ORYRU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.61	345	213	13	65	393	1422	1728	8e-09	68.6
rs:WP_041890423	DNA topoisomerase I [candidate division SR1 bacterium MGEHA].	24.40	291	180	8	50	334	222	478	9e-09	68.2
rs:WP_027124448	DNA topoisomerase I [Gelidibacter mesophilus].	26.89	264	151	9	77	334	249	476	9e-09	68.2
tr:L0NDR6_RHISP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.83	443	262	15	47	452	230	638	9e-09	68.2
rs:XP_011522302	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Homo sapiens].	26.86	242	149	6	59	294	309	528	9e-09	67.8
rs:WP_036863604	DNA topoisomerase I [Porphyromonas sp. COT-108 OH2963].	26.74	258	146	7	86	334	258	481	9e-09	68.2
rs:WP_020757403	DNA topoisomerase, partial [Gardnerella vaginalis].	27.27	341	200	13	77	404	67	372	9e-09	68.2
tr:U5NGH4_9MOLU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00003390}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.94	405	238	14	72	452	262	624	9e-09	68.2
rs:WP_033992850	hypothetical protein, partial [Pseudomonas aeruginosa].	24.87	394	219	17	77	446	245	585	9e-09	68.2
rs:WP_037317256	DNA topoisomerase I [Salegentibacter sp. Hel_I_6].	25.74	272	163	8	68	334	241	478	9e-09	68.2
rs:WP_040917580	DNA topoisomerase I [Leptospira meyeri].	23.89	314	176	11	61	354	225	495	9e-09	68.2
rs:WP_014796302	DNA topoisomerase I [Flexibacter litoralis].	24.63	268	162	7	77	335	249	485	9e-09	68.2
rs:WP_034692419	DNA topoisomerase I [Chryseobacterium sp. CF365].	26.57	286	167	10	51	334	232	476	9e-09	68.2
rs:WP_004766649	DNA topoisomerase I [Leptospira kirschneri].	22.27	449	277	17	31	450	197	602	9e-09	68.2
rs:WP_043896112	DNA topoisomerase I [Mycoplasma parvum].	24.94	405	238	14	72	452	266	628	9e-09	68.2
tr:R0M9K0_NOSB1	SubName: Full=DNA topoisomerase 3-alpha {ECO:0000313|EMBL:EOB14659.1};	25.15	342	210	11	40	374	244	546	9e-09	68.2
rs:XP_008792957	PREDICTED: DNA topoisomerase 3-beta isoform X4 [Phoenix dactylifera].	22.97	344	213	11	65	393	127	433	9e-09	68.2
rs:XP_002460479	hypothetical protein SORBIDRAFT_02g029000 [Sorghum bicolor].	22.72	383	228	15	65	425	282	618	9e-09	68.2
rs:XP_004202179	Piso0_001663 [Millerozyma farinosa CBS 7064].	24.07	324	205	7	73	385	292	585	9e-09	68.2
tr:A6EMW3_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.09	279	172	7	61	334	233	479	9e-09	68.2
rs:XP_008219962	PREDICTED: uncharacterized protein LOC103320114 [Prunus mume].	23.87	444	268	17	54	458	601	1013	9e-09	68.2
rs:WP_044547706	DNA topoisomerase I, partial [Parabacteroides distasonis].	33.12	154	94	4	275	427	3	148	9e-09	65.5
rs:WP_035698473	DNA topoisomerase I, partial [Glycomyces tenuis].	26.97	304	181	9	42	334	255	528	9e-09	67.8
rs:WP_006707234	DNA topoisomerase I, partial [Candidatus Regiella insecticola].	25.23	321	196	10	77	387	293	579	9e-09	68.2
rs:WP_014709083	DNA topoisomerase I [Prevotella intermedia].	24.63	268	160	7	77	334	252	487	9e-09	68.2
rs:WP_011282147	DNA topoisomerase I [Candidatus Pelagibacter ubique].	24.21	442	270	16	43	454	226	632	9e-09	68.2
tr:A0A084AY93_STACH	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KEY70272.1};	24.10	307	188	9	37	335	283	552	9e-09	68.2
rs:WP_034576267	DNA topoisomerase I [Cardinium endosymbiont of Bemisia tabaci].	26.59	267	160	8	77	340	249	482	9e-09	68.2
tr:B8BD52_ORYSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.62	367	228	13	44	393	263	590	9e-09	68.2
rs:WP_027066041	DNA topoisomerase I [Maribacter sp. Hel_I_7].	26.67	270	161	9	77	340	249	487	9e-09	68.2
rs:WP_036845096	MULTISPECIES: DNA topoisomerase I [Porphyromonas].	26.74	258	146	7	86	334	258	481	9e-09	68.2
rs:WP_034260918	DNA topoisomerase I [Altibacter lentus].	25.25	301	174	10	65	351	238	501	1e-08	68.2
rs:WP_022935662	DNA topoisomerase I [Mycoplasma moatsii].	23.06	399	209	13	84	449	258	591	1e-08	67.8
tr:J9Z2K6_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.27	412	241	16	77	452	259	635	1e-08	68.2
rs:WP_026704084	DNA topoisomerase I [Flavobacterium soli].	27.92	265	147	9	77	334	249	476	1e-08	68.2
tr:A0A0F3R601_ORITS	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:KJW01880.1};	27.22	158	88	3	223	377	49	182	1e-08	65.1
rs:XP_008792956	PREDICTED: DNA topoisomerase 3-beta isoform X3 [Phoenix dactylifera].	22.97	344	213	11	65	393	225	531	1e-08	68.2
rs:XP_008076085	Prokaryotic type I DNA topoisomerase [Glarea lozoyensis ATCC 20868].	23.84	302	197	7	40	339	265	535	1e-08	67.8
rs:XP_008792952	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Phoenix dactylifera].	22.97	344	213	11	65	393	284	590	1e-08	68.2
rs:WP_038561788	DNA topoisomerase I [Mycoplasma californicum].	24.80	371	209	14	101	452	281	600	1e-08	67.8
rs:XP_008792955	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Phoenix dactylifera].	22.97	344	213	11	65	393	243	549	1e-08	68.2
tr:H2Z236_CIOSA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.50	302	185	10	60	353	234	503	1e-08	68.2
rs:WP_041103025	DNA topoisomerase I [Mycoplasma californicum].	24.80	371	209	14	101	452	281	600	1e-08	67.8
rs:WP_038608548	DNA topoisomerase I [Bacteroides dorei].	24.62	260	164	6	77	334	253	482	1e-08	68.2
rs:WP_013306390	DNA topoisomerase I [Maribacter sp. HTCC2170].	25.09	291	184	7	47	334	219	478	1e-08	68.2
rs:WP_026429052	DNA topoisomerase I [Actinotignum schaalii].	25.00	372	219	14	40	387	248	583	1e-08	68.2
rs:WP_023127875	DNA topoisomerase I [Pseudomonas aeruginosa].	25.74	303	185	8	166	459	337	608	1e-08	67.8
rs:WP_041485569	hypothetical protein, partial [alpha proteobacterium HIMB59].	24.27	412	241	16	77	452	259	635	1e-08	68.2
sp:TOP1_BUCAP	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	22.22	342	217	11	47	381	248	547	1e-08	68.2
tr:A0A0A8RQR3_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.23	409	246	13	41	419	254	624	1e-08	68.2
rs:WP_036940538	DNA topoisomerase I [Propionibacterium freudenreichii].	23.23	409	246	13	41	419	254	624	1e-08	68.2
rs:WP_007705251	topoisomerase IA, partial [Sphingobium sp. AP49].	27.20	250	133	10	223	452	11	231	1e-08	67.4
tr:A0A0D3H8J7_9ORYZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.61	345	213	13	65	393	1197	1503	1e-08	68.2
rs:WP_021583487	topoisomerase repeat protein, partial [Prevotella pleuritidis].	39.64	111	65	2	275	384	4	113	1e-08	65.1
rs:WP_025307436	DNA topoisomerase I [Bdellovibrio bacteriovorus].	23.49	315	209	7	77	385	293	581	1e-08	68.2
rs:WP_006709922	DNA topoisomerase, partial [Serratia symbiotica].	34.62	104	68	0	36	139	21	124	1e-08	64.3
rs:WP_032840057	DNA topoisomerase I, partial [Gardnerella vaginalis].	25.96	366	222	13	71	422	9	339	1e-08	66.6
rs:WP_036452389	DNA topoisomerase I [Mycoplasma iowae].	21.46	396	257	10	76	454	270	628	1e-08	67.8
rs:WP_010979235	DNA topoisomerase I [Sulfolobus tokodaii].	23.65	389	248	13	47	424	251	601	1e-08	67.8
rs:XP_505752	YALI0F22495p [Yarrowia lipolytica].	23.70	405	242	14	10	385	224	590	1e-08	67.8
rs:WP_035237944	DNA topoisomerase, partial [Acidobacteriaceae bacterium URHE0068].	23.93	351	222	11	23	354	222	546	1e-08	67.8
rs:XP_006596164	PREDICTED: uncharacterized protein LOC100778913 [Glycine max].	21.62	495	316	16	3	458	460	921	1e-08	68.2
rs:WP_027420405	DNA topoisomerase I [Crocinitomix catalasitica].	23.99	296	187	7	43	334	214	475	1e-08	67.8
tr:B5VNF1_YEAS6	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.54	368	201	12	42	380	118	441	1e-08	67.4
rs:XP_003061949	predicted protein [Micromonas pusilla CCMP1545].	23.86	352	210	12	61	392	286	599	1e-08	67.8
tr:G4EM68_MYCIO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.46	396	257	10	76	454	270	628	1e-08	67.8
tr:A0A0D4UCW2_YEASX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.59	340	185	11	42	357	296	591	1e-08	67.8
tr:A0A0D4UBD9_YEASX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.54	368	201	12	42	380	296	619	1e-08	67.8
rs:WP_047552390	DNA topoisomerase I [Methylotenera sp. G11].	24.46	413	247	15	60	449	246	616	1e-08	67.8
rs:WP_026966063	DNA topoisomerase I [Algoriphagus terrigena].	23.13	281	178	6	60	334	231	479	1e-08	67.8
tr:A0A069D168_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.12	268	162	9	77	340	253	488	1e-08	67.8
rs:WP_007648109	DNA topoisomerase I [Formosa sp. AK20].	25.71	280	166	8	61	334	233	476	1e-08	67.8
tr:K1S5B8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC50674.1}; Flags: Fragment;	33.33	102	65	3	71	171	82	181	1e-08	64.7
tr:A0A0D2PB21_9AGAR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.42	363	222	11	41	387	261	583	1e-08	67.8
tr:A0A0D4UPY3_YEASX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.54	368	201	12	42	380	296	619	1e-08	67.8
tr:A0A0A8PWE8_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.23	409	246	13	41	419	254	624	1e-08	67.8
tr:A0A0A8TBV7_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.23	409	246	13	41	419	254	624	1e-08	67.8
rs:XP_007879644	hypothetical protein PFL1_03930 [Pseudozyma flocculosa PF-1].	23.56	331	201	10	39	357	272	562	1e-08	67.8
rs:XP_003675634	hypothetical protein NCAS_0C02780 [Naumovozyma castellii CBS 4309].	26.80	250	148	5	166	406	428	651	1e-08	67.8
rs:WP_034781453	hypothetical protein, partial [Bacteroides graminisolvens].	26.12	268	162	9	77	340	253	488	1e-08	67.8
tr:A0A0D4VXN5_YEASX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.54	368	201	12	42	380	296	619	1e-08	67.4
tr:A0A0D4TS41_YEASX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.54	368	201	12	42	380	296	619	1e-08	67.4
rs:WP_035939843	DNA topoisomerase I [Knoellia aerolata].	25.95	343	206	10	31	356	246	557	1e-08	67.8
rs:XP_010247446	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Nelumbo nucifera].	23.69	325	198	12	37	351	250	534	1e-08	67.8
rs:WP_038991676	DNA topoisomerase I [Arthrobacter sp. W1].	24.77	327	207	9	42	356	259	558	1e-08	67.8
rs:WP_024267208	DNA topoisomerase I [Salinispira pacifica].	25.31	324	207	7	38	354	253	548	1e-08	67.8
rs:NP_986566	AGL101Cp [Ashbya gossypii ATCC 10895].	23.08	351	229	9	40	378	271	592	1e-08	67.4
rs:XP_006661399	PREDICTED: DNA topoisomerase 3-beta-1-like [Oryza brachyantha].	23.12	346	210	13	65	393	399	705	1e-08	67.8
rs:WP_044496677	DNA topoisomerase III, partial [Peptoclostridium difficile].	29.49	156	104	3	40	193	228	379	1e-08	67.0
tr:K2FS61_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.76	420	253	17	47	450	245	617	1e-08	67.8
rs:WP_023110927	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	25.17	286	180	7	74	354	260	516	1e-08	67.4
tr:A0A078B952_STYLE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.80	367	228	14	39	386	721	1047	1e-08	67.8
tr:K1RLQ8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC46343.1}; Flags: Fragment;	35.14	148	80	5	286	428	1	137	1e-08	65.1
tr:X1J3S8_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S14849 {ECO:0000313|EMBL:GAH72974.1}; Flags: Fragment;	28.34	247	140	9	211	452	13	227	1e-08	65.5
rs:WP_002409541	hypothetical protein, partial [Enterococcus faecalis].	31.36	169	99	5	52	212	7	166	1e-08	64.3
rs:WP_010549533	DNA topoisomerase I [Brachybacterium paraconglomeratum].	24.70	328	207	8	41	356	253	552	1e-08	67.8
rs:WP_035949104	DNA topoisomerase I [Knoellia flava].	24.85	342	203	11	38	356	244	554	1e-08	67.8
rs:XP_003296497	hypothetical protein PTT_06616 [Pyrenophora teres f. teres 0-1].	25.00	272	160	7	73	337	300	534	1e-08	67.4
rs:WP_042916887	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	25.17	286	180	7	74	354	260	516	1e-08	67.4
rs:WP_024930446	DNA topoisomerase I [Methylophilus sp. OH31].	23.37	415	251	14	60	449	246	618	1e-08	67.8
rs:XP_005714936	DNA topoisomerase I Mitochondrial [Chondrus crispus].	23.81	315	193	9	41	341	285	566	1e-08	67.8
rs:WP_044171393	DNA topoisomerase I [Flectobacillus major].	27.37	274	157	8	68	335	240	477	1e-08	67.8
tr:F2BVU4_9FIRM	SubName: Full=DNA topoisomerase TopA {ECO:0000313|EMBL:EGF15620.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EGF15620.1};	27.32	205	118	6	255	454	2	180	1e-08	66.2
rs:WP_045167865	DNA topoisomerase I [Prevotella intermedia].	24.25	268	161	6	77	334	252	487	1e-08	67.4
tr:A0A090R8L7_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	38.57	70	43	0	54	123	1	70	1e-08	62.4
rs:WP_027333036	DNA topoisomerase I [Mycoplasma gallinarum].	24.59	370	209	13	101	452	286	603	1e-08	67.4
rs:WP_047515103	DNA topoisomerase I [Methylophilus sp. Q8].	23.37	415	251	14	60	449	246	618	1e-08	67.8
gpu:CP011209_179	topoisomerase I, DNA topoisomerase I protein [Parcubacteria (Wolfebacteria) bacterium GW2011_GWB1_47_1]	23.47	426	266	15	43	452	226	607	1e-08	67.4
rs:WP_019881158	MULTISPECIES: DNA topoisomerase I [Methylophilus].	23.37	415	251	14	60	449	246	618	1e-08	67.4
rs:WP_009776219	DNA topoisomerase I [Janibacter sp. HTCC2649].	25.41	370	223	12	31	379	243	580	1e-08	67.8
tr:A0A093VE97_PENMA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	27.24	246	142	9	97	342	210	418	1e-08	67.0
tr:F7JLD5_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGN30496.1};	35.65	115	72	1	311	425	14	126	1e-08	64.7
tr:A0A093Y038_PENMA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.24	246	142	9	97	342	309	517	1e-08	67.0
rs:XP_010247445	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Nelumbo nucifera].	23.69	325	198	12	37	351	253	537	1e-08	67.4
tr:A0A0B7JSA1_BIOOC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CEO45391.1};	25.33	304	182	10	40	335	257	523	1e-08	67.4
rs:WP_033628389	DNA topoisomerase, partial [Enterococcus faecalis].	30.87	149	87	4	316	455	1	142	2e-08	64.3
rs:WP_009388753	DNA topoisomerase I [Capnocytophaga sp. oral taxon 329].	22.76	312	196	8	35	334	198	476	2e-08	67.4
tr:I1QQ61_ORYGL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.83	346	211	13	65	393	284	590	2e-08	67.4
tr:C0B3Z2_9ENTR	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEG83390.1};	28.02	232	130	8	166	386	26	231	2e-08	65.1
tr:X1FH45_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_C01715 {ECO:0000313|EMBL:GAH20103.1}; Flags: Fragment;	25.61	246	127	6	243	450	6	233	2e-08	65.9
sp:TOP3B_ORYSJ	RecName: Full=DNA topoisomerase 3-beta; EC=5.99.1.2;	22.83	346	211	13	65	393	284	590	2e-08	67.4
rs:XP_008091224	DNA topoisomerase [Colletotrichum graminicola M1.001].	23.84	302	197	8	37	336	254	524	2e-08	67.4
tr:K1SDT3_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central domain protein {ECO:0000313|EMBL:EKC51825.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EKC51825.1};	38.64	88	49	2	154	236	11	98	2e-08	63.2
rs:XP_006667060	DNA topoisomerase III [Cordyceps militaris CM01].	24.85	334	206	13	10	335	173	469	2e-08	67.4
rs:WP_034646182	DNA topoisomerase I [Cellulophaga geojensis].	25.18	282	176	7	56	334	228	477	2e-08	67.4
rs:WP_042107570	DNA topoisomerase III, partial [Escherichia coli].	40.48	84	50	0	302	385	1	84	2e-08	63.5
rs:WP_038504905	DNA topoisomerase I [Cellulophaga lytica].	25.18	282	176	7	56	334	228	477	2e-08	67.4
rs:WP_006886374	DNA topoisomerase I [Mycoplasma anatis].	24.41	381	217	12	92	452	269	598	2e-08	67.0
rs:WP_009416627	DNA topoisomerase I [Capnocytophaga sp. oral taxon 332].	24.84	310	188	10	37	334	200	476	2e-08	67.4
rs:WP_040538233	DNA topoisomerase I, partial [Mycoplasma iowae].	21.46	396	257	10	76	454	270	628	2e-08	67.4
rs:WP_038013874	DNA topoisomerase I [Synechococcus sp. WH 8016].	23.73	375	235	9	37	389	246	591	2e-08	67.4
rs:WP_013620341	DNA topoisomerase I [Cellulophaga lytica].	25.18	282	176	7	56	334	228	477	2e-08	67.4
rs:WP_012274955	hypothetical protein [Collimonas fungivorans].	24.50	400	252	14	70	459	252	611	2e-08	67.4
tr:G4FJ28_9SYNE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.73	375	235	9	37	389	269	614	2e-08	67.4
rs:WP_014084443	DNA topoisomerase I [Flavobacterium branchiophilum].	26.79	280	165	8	60	334	232	476	2e-08	67.4
rs:WP_046783664	topoisomerase I, partial [Lactobacillus plantarum].	30.95	126	73	3	160	280	13	129	2e-08	63.5
rs:WP_036528634	DNA topoisomerase I [Nocardia sp. CNY236].	25.00	324	193	10	45	356	291	576	2e-08	67.4
rs:WP_033659008	DNA topoisomerase, partial [Enterococcus faecium].	42.35	85	46	1	281	365	1	82	2e-08	64.7
tr:A0A066WYU1_COLSU	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:KDN60579.1};	24.91	273	173	7	65	336	283	524	2e-08	67.0
rs:WP_019286527	hypothetical protein, partial [Rhodococcus sp. R04].	27.52	367	200	15	35	377	254	578	2e-08	67.0
rs:WP_031445426	DNA topoisomerase I [Arenibacter algicola].	23.75	341	221	10	1	334	170	478	2e-08	67.4
gp:CP007339_850	hypothetical protein [Salmonella enterica subsp. enterica serovar Enteritidis str.]	31.97	147	71	5	211	356	3	121	2e-08	63.5
tr:G4VM01_SCHMA	SubName: Full=Putative prokaryotic DNA topoisomerase {ECO:0000313|EMBL:CCD80506.1};	24.01	379	216	12	22	377	260	589	2e-08	67.4
tr:J3MYW0_ORYBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.12	346	210	13	65	393	284	590	2e-08	67.4
rs:WP_042858573	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	25.00	268	154	8	212	459	7	247	2e-08	65.1
rs:XP_005706261	DNA topoisomerase III alpha [Galdieria sulphuraria].	23.40	329	203	11	61	377	315	606	2e-08	67.0
gpu:CP011210_314	topoisomerase I, DNA topoisomerase I protein [Microgenomates (Beckwithbacteria) bacterium GW2011_GWC1_49_16]	23.72	430	258	15	47	452	226	609	2e-08	67.0
rs:XP_005706718	DNA topoisomerase III alpha [Galdieria sulphuraria].	22.68	366	216	12	37	377	261	584	2e-08	67.0
rs:WP_012007264	DNA topoisomerase I [Prochlorococcus marinus].	25.42	358	209	15	48	393	267	578	2e-08	67.0
rs:XP_001690341	DNA topoisomerase-like protein, partial [Chlamydomonas reinhardtii].	24.94	433	264	14	45	446	248	650	2e-08	67.0
rs:WP_047163065	hypothetical protein, partial [Trichodesmium erythraeum].	39.33	89	49	2	277	365	25	108	2e-08	62.8
tr:G9X9X9_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHL20225.1};	29.19	185	100	5	278	457	19	177	2e-08	64.7
rs:WP_034303586	DNA topoisomerase III, partial [Bacillus sp. 123MFChir2].	28.68	136	93	3	36	169	244	377	2e-08	66.2
rs:WP_007096527	DNA topoisomerase I [Kordia algicida].	25.78	322	188	9	47	350	219	507	2e-08	67.0
tr:S4H2A9_GARVA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	29.61	206	115	6	220	422	125	303	2e-08	65.5
rs:XP_005707982	DNA topoisomerase I [Galdieria sulphuraria].	25.53	333	195	14	74	379	399	705	2e-08	67.0
rs:XP_008439059	PREDICTED: DNA topoisomerase 3-beta-1 [Cucumis melo].	22.94	340	223	11	18	351	232	538	2e-08	67.0
rs:WP_013406929	DNA topoisomerase I [Leadbetterella byssophila].	26.82	261	157	7	77	335	251	479	2e-08	67.0
rs:WP_037330088	hypothetical protein, partial [Anaerovibrio lipolyticus].	24.29	420	246	16	65	457	285	659	2e-08	67.0
rs:WP_045182440	DNA topoisomerase I [Elizabethkingia sp. BM10].	26.71	322	188	10	36	350	217	497	2e-08	67.0
rs:WP_036735187	DNA topoisomerase I, partial [Peptococcaceae bacterium SCADC1_2_3].	26.24	282	161	11	65	330	242	492	2e-08	66.6
rs:XP_009546939	hypothetical protein HETIRDRAFT_46055 [Heterobasidion irregulare TC 32-1].	24.68	389	217	14	39	393	255	601	2e-08	67.0
rs:WP_012902943	DNA topoisomerase I [Rothia mucilaginosa].	25.42	295	172	12	77	354	290	553	2e-08	67.0
rs:XP_003078306	DNA topoisomerase III alpha, putative (ISS) [Ostreococcus tauri].	23.71	329	213	11	37	351	263	567	2e-08	67.0
tr:X0QTV8_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.59	297	169	11	61	347	294	548	2e-08	66.6
rs:XP_007225278	hypothetical protein PRUPE_ppa001428mg [Prunus persica].	23.65	444	269	17	54	458	264	676	2e-08	67.0
rs:WP_002350893	hypothetical protein, partial [Enterococcus faecium].	37.07	116	67	4	281	392	1	114	2e-08	64.7
tr:S0DUX7_GIBF5	SubName: Full=Related to DNA topoisomerase III {ECO:0000313|EMBL:CCT66255.1};	24.73	283	169	7	60	335	278	523	2e-08	66.6
tr:V6TP11_GIAIN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESU40102.1}; Flags: Fragment;	22.99	361	218	13	61	387	188	522	2e-08	67.0
rs:WP_034509367	DNA topoisomerase I [Blastococcus sp. URHD0036].	24.85	330	203	10	42	354	291	592	2e-08	67.0
rs:WP_005508282	DNA topoisomerase I [Rothia mucilaginosa].	25.42	295	172	12	77	354	290	553	2e-08	67.0
rs:WP_043497076	DNA topoisomerase I [Georgenia sp. SUBG003].	26.56	305	169	12	77	358	296	568	2e-08	67.0
rs:WP_032839579	DNA topoisomerase I, partial [Gardnerella vaginalis].	26.81	317	188	12	71	376	1	284	2e-08	65.9
tr:A0A0D2XE89_FUSO4	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblFungi:FOXG_02220P0};	25.35	284	168	8	59	335	142	388	2e-08	66.6
rs:XP_002516387	prokaryotic DNA topoisomerase, putative [Ricinus communis].	23.29	322	197	12	40	351	257	538	2e-08	67.0
rs:WP_015266922	DNA topoisomerase I [Echinicola vietnamensis].	26.62	263	157	8	77	334	248	479	2e-08	67.0
tr:F3EPM0_PSEAV	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGH88126.1}; Flags: Fragment;	42.42	66	37	1	117	181	1	66	2e-08	61.6
rs:WP_018338119	DNA topoisomerase I [Butyricimonas synergistica].	29.23	260	151	7	77	334	253	481	2e-08	67.0
tr:A0A024GVE1_9STRA	SubName: Full=Albugo candida WGS project CAIX00000000 data, strain Ac Nc2, contig AcNc2_CONTIG_579_length_13152 {ECO:0000313|EMBL:CCI50571.1};	23.58	352	219	12	40	377	261	576	2e-08	67.0
tr:X1M7D1_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_C05056 {ECO:0000313|EMBL:GAI10595.1}; Flags: Fragment;	25.28	269	155	7	110	358	8	250	2e-08	64.7
tr:R8ULT3_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	36.36	88	56	0	48	135	134	221	2e-08	64.3
rs:WP_036883715	DNA topoisomerase I [Porphyromonas gingivicanis].	24.44	266	168	7	77	340	252	486	2e-08	67.0
tr:I7BKR0_MYCHA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00003390}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.62	398	244	13	72	450	266	626	2e-08	67.0
rs:WP_048348273	DNA topoisomerase I [Synechococcus sp. WH 8020].	23.44	384	241	10	30	389	237	591	2e-08	67.0
tr:B9G4E5_ORYSJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.83	346	211	13	65	393	147	453	2e-08	66.6
rs:WP_005942683	DNA topoisomerase III [Bacteroides massiliensis].	24.32	329	217	8	61	385	262	562	2e-08	66.6
rs:WP_047754068	DNA topoisomerase I [Kosmotoga pacifica].	25.28	356	195	14	48	376	222	533	2e-08	66.6
rs:WP_042866267	DNA topoisomerase III, partial [Bacillus cereus].	36.36	88	56	0	48	135	140	227	2e-08	64.7
rs:WP_004837937	hypothetical protein, partial [Anaerococcus tetradius].	33.80	142	77	6	65	203	23	150	2e-08	63.2
rs:XP_004922832	PREDICTED: DNA topoisomerase 3-beta-1 [Bombyx mori].	21.82	362	241	12	40	393	262	589	2e-08	67.0
rs:WP_009745737	DNA topoisomerase I [Capnocytophaga sp. oral taxon 338].	23.15	311	196	7	35	334	198	476	2e-08	67.0
rs:WP_047267500	DNA topoisomerase I [Marinitoga sp. 1197].	23.25	486	263	19	42	454	220	668	2e-08	66.6
rs:WP_022864544	DNA topoisomerase I [Varibaculum cambriense].	25.00	356	210	12	30	362	236	557	3e-08	67.0
tr:V6TTM7_GIAIN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESU40370.1};	22.99	361	218	13	61	387	277	611	3e-08	67.0
tr:W1DVX7_KLEPN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CDL12870.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDL12870.1};	31.07	103	65	1	182	284	3	99	3e-08	62.8
tr:X0B8D7_FUSOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EXK41406.1};	25.44	283	167	8	60	335	278	523	3e-08	66.6
rs:WP_022541864	DNA topoisomerase I [Aeropyrum camini].	26.69	326	186	11	65	377	284	569	3e-08	66.6
rs:XP_001851071	DNA topoisomerase 3-beta [Culex quinquefasciatus].	24.52	465	269	22	18	453	235	646	3e-08	66.6
rs:WP_005504709	DNA topoisomerase I [Rothia mucilaginosa].	25.42	295	172	12	77	354	290	553	3e-08	66.6
tr:Q2SD25_HAHCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.86	420	264	14	40	446	270	642	3e-08	66.6
rs:WP_039207818	hypothetical protein, partial [Anaerovibrio lipolyticus].	24.29	420	246	16	65	457	275	649	3e-08	66.6
rs:WP_041598850	DNA topoisomerase I [Hahella chejuensis].	22.86	420	264	14	40	446	257	629	3e-08	66.6
rs:WP_008637200	DNA topoisomerase I [Bizionia argentinensis].	24.73	279	170	7	61	334	233	476	3e-08	66.6
rs:WP_009779100	DNA topoisomerase I [Leeuwenhoekiella blandensis].	25.35	284	164	10	60	334	232	476	3e-08	66.6
tr:C2FZU9_9SPHI	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEI91545.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EEI91545.1};	32.12	137	74	5	70	197	272	398	3e-08	65.9
rs:WP_025306605	DNA topoisomerase I [Thermocrinis ruber].	25.32	312	184	9	74	377	240	510	3e-08	66.2
rs:WP_033422723	hypothetical protein, partial [Empedobacter brevis].	25.82	244	156	7	74	311	73	297	3e-08	65.9
tr:A9YJ49_DROME	SubName: Full=Topoisomerase 3 beta {ECO:0000313|EMBL:ABW92701.1}; Flags: Fragment;	26.36	220	129	8	167	381	47	238	3e-08	64.7
tr:W9IXD5_FUSOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EWY97960.1};	25.35	284	168	8	59	335	277	523	3e-08	66.6
rs:WP_035125554	DNA topoisomerase I [Flavobacterium aquatile].	27.00	263	152	8	77	334	249	476	3e-08	66.6
tr:R3GZL3_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	40.28	72	43	0	47	118	243	314	3e-08	65.5
tr:W1GEU2_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.88	187	103	6	166	348	64	224	3e-08	65.1
rs:WP_011163504	DNA topoisomerase I [Bdellovibrio bacteriovorus].	22.33	318	209	7	77	385	294	582	3e-08	66.6
rs:WP_034861517	DNA topoisomerase I [Enterobacteriaceae bacterium B14].	23.68	380	239	14	77	446	284	622	3e-08	66.6
tr:X0ACK9_FUSOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EXK41405.1};	25.35	284	168	8	59	335	277	523	3e-08	66.6
tr:W9PVS6_FUSOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EXA49324.1};	25.44	283	167	8	60	335	278	523	3e-08	66.6
rs:XP_002946547	hypothetical protein VOLCADRAFT_115956 [Volvox carteri f. nagariensis].	22.98	383	224	11	46	386	391	744	3e-08	66.6
rs:WP_033498327	DNA topoisomerase I [Bifidobacterium coryneforme].	24.63	337	200	10	42	354	262	568	3e-08	66.6
tr:A0A0D4UHK0_YEASX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.29	340	186	11	42	357	296	591	3e-08	66.6
tr:W9ITG9_FUSOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EWY97962.1};	25.44	283	167	8	60	335	278	523	3e-08	66.6
tr:H1LSH5_9FIRM	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EHO54341.1};	24.01	279	180	7	179	454	3	252	3e-08	65.5
rs:XP_007587660	putative dna topoisomerase iii protein [Neofusicoccum parvum UCRNP2].	24.16	269	168	7	73	337	291	527	3e-08	66.2
tr:W9N470_FUSOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EWZ99087.1};	25.44	283	167	8	60	335	278	523	3e-08	66.2
rs:WP_031430985	hypothetical protein [Vibrio parahaemolyticus].	22.50	320	211	7	84	383	306	608	3e-08	66.6
rs:WP_046835524	hypothetical protein [Pseudomonas amygdali].	32.06	131	80	2	199	323	70	197	3e-08	64.7
tr:K2CUE4_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	27.69	260	157	9	46	289	234	478	3e-08	66.2
rs:WP_036191546	DNA topoisomerase I [Lysobacter concretionis].	26.37	311	168	12	69	354	255	529	3e-08	66.6
rs:WP_034327379	MULTISPECIES: TopA [Helicobacter].	23.26	301	186	8	65	354	246	512	3e-08	66.2
tr:F9FBF1_FUSOF	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGU85855.1};	25.44	283	167	8	60	335	278	523	3e-08	66.2
tr:X0MUK6_FUSOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EXM37236.1};	25.35	284	168	8	59	335	277	523	3e-08	66.2
rs:WP_002952543	TopA [Campylobacter showae].	23.99	346	211	13	59	385	232	544	3e-08	66.2
tr:W9NBU3_FUSOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EWZ99086.1};	25.35	284	168	8	59	335	277	523	3e-08	66.2
rs:WP_031307068	DNA topoisomerase I [Brachybacterium muris].	26.88	346	202	13	50	377	262	574	3e-08	66.6
tr:T0ZHK4_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EQD43907.1}; Flags: Fragment;	26.40	197	116	6	166	356	5	178	3e-08	65.1
rs:WP_016762302	DNA topoisomerase I [Leptospira kirschneri].	22.05	449	278	17	31	450	197	602	3e-08	66.2
tr:M5G9P4_DACSP	SubName: Full=Prokaryotic type I DNA topoisomerase {ECO:0000313|EMBL:EJU05529.1};	24.28	383	224	13	39	397	252	592	3e-08	66.6
tr:A0A0D2DXX3_9EURO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.43	370	237	10	45	395	285	623	3e-08	66.2
rs:WP_035675539	DNA topoisomerase I [Flavobacterium frigidarium].	27.38	263	151	8	77	334	249	476	3e-08	66.6
rs:WP_002079051	DNA topoisomerase I [Leptospira interrogans].	22.53	435	270	16	40	450	211	602	3e-08	66.2
rs:WP_021601090	DNA topoisomerase I [Actinobaculum sp. oral taxon 183].	26.14	329	194	10	77	384	282	582	3e-08	66.6
rs:XP_011462844	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Fragaria vesca subsp. vesca].	22.59	394	236	15	65	434	224	572	3e-08	66.2
rs:WP_016170258	hypothetical protein [Parcubacteria bacterium SCGC AAA011-G05].	24.03	412	238	17	65	452	250	610	3e-08	66.2
rs:WP_004574556	DNA topoisomerase I [Gardnerella vaginalis].	26.81	317	188	12	71	376	282	565	3e-08	66.6
rs:WP_028887838	DNA topoisomerase I [Tenacibaculum ovolyticum].	25.54	278	171	8	60	334	232	476	3e-08	66.2
tr:W9PW21_FUSOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EXA49323.1};	25.35	284	168	8	59	335	277	523	3e-08	66.2
rs:XP_008034473	prokaryotic type I DNA topoisomerase [Trametes versicolor FP-101664 SS1].	25.69	327	191	13	39	353	258	544	3e-08	66.6
tr:X0IMU8_FUSOX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EXL85446.1};	25.35	284	168	8	59	335	277	523	3e-08	66.2
rs:WP_043424200	hypothetical protein, partial [Streptomyces pluripotens].	41.57	89	45	3	38	123	39	123	3e-08	62.4
rs:WP_040235479	DNA topoisomerase III, partial [Klebsiella pneumoniae].	38.20	89	53	1	27	115	239	325	3e-08	65.1
tr:A0A0D9XFA6_9ORYZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.83	346	211	13	65	393	248	554	3e-08	66.2
rs:WP_040380902	hypothetical protein, partial [Deinococcus aquatilis].	26.38	326	194	12	86	403	295	582	3e-08	66.2
rs:WP_016544013	DNA topoisomerase I [Leptospira wolffii].	20.40	397	252	10	74	449	249	602	3e-08	66.2
rs:WP_019159531	DNA topoisomerase I [Brevibacterium senegalense].	25.41	303	178	9	77	356	294	571	4e-08	66.2
rs:WP_004837938	hypothetical protein, partial [Anaerococcus tetradius].	34.48	145	72	7	65	203	23	150	4e-08	62.8
rs:WP_008778772	DNA topoisomerase III [Parabacteroides sp. 20_3].	24.32	329	217	8	61	385	262	562	4e-08	66.2
rs:WP_019036494	hypothetical protein, partial [Prevotella amnii].	30.00	130	78	3	74	203	284	400	4e-08	65.5
tr:S4PI25_9PORP	SubName: Full=DNA topoisomerase III, Bacteroidales-type {ECO:0000313|EMBL:GAD06917.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAD06917.1};	26.89	212	140	7	79	280	1	207	4e-08	64.3
rs:WP_022406180	DNA topoisomerase [Prevotella sp. CAG:485].	25.87	344	208	11	35	356	211	529	4e-08	66.2
rs:WP_003524692	hypothetical protein, partial [[Clostridium] clostridioforme].	29.79	141	94	3	34	173	224	360	4e-08	65.5
tr:A0A0B0EM62_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.22	267	167	8	71	334	242	481	4e-08	66.2
rs:WP_045945856	DNA topoisomerase I, partial [Streptomyces katrae].	31.85	135	73	3	220	354	17	132	4e-08	65.9
rs:XP_004957260	PREDICTED: DNA topoisomerase 3-beta [Setaria italica].	21.73	382	233	14	65	425	284	620	4e-08	66.2
tr:A9YJ44_DROME	SubName: Full=CG3458 {ECO:0000313|EMBL:ADG51438.1}; SubName: Full=Topoisomerase 3 beta {ECO:0000313|EMBL:ABW92696.1}; Flags: Fragment;	26.36	220	129	8	167	381	47	238	4e-08	64.3
rs:XP_012649667	uncharacterized protein [Babesia microti strain RI].	23.73	316	204	9	39	350	256	538	4e-08	65.9
rs:WP_022857371	DNA topoisomerase I [Alloscardovia omnicolens].	25.90	363	219	12	41	387	254	582	4e-08	66.2
rs:WP_025743036	DNA topoisomerase I [Aquimarina pacifica].	27.34	278	157	12	68	338	241	480	4e-08	66.2
rs:WP_040580726	DNA topoisomerase I [Porphyromonas endodontalis].	25.00	260	164	6	77	334	252	482	4e-08	66.2
rs:WP_031788636	hypothetical protein [Staphylococcus aureus].	29.38	160	103	5	293	450	1	152	4e-08	63.5
rs:WP_016874429	DNA topoisomerase I [Chlorogloeopsis fritschii].	21.95	410	252	11	41	429	242	604	4e-08	66.2
rs:XP_003671229	hypothetical protein NDAI_0G02110 [Naumovozyma dairenensis CBS 421].	26.35	353	197	14	73	401	319	632	4e-08	65.9
rs:WP_011738364	DNA topoisomerase I [Candidatus Ruthia magnifica].	23.34	347	214	10	2	334	163	471	4e-08	66.2
rs:WP_031839729	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	26.42	246	145	8	206	446	7	221	4e-08	65.5
tr:U1QX25_9BIFI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.90	363	219	12	41	387	268	596	4e-08	66.2
rs:WP_006812921	topoisomerase I [Providencia rustigianii].	25.00	320	196	9	77	386	291	576	4e-08	66.2
rs:XP_004296978	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Fragaria vesca subsp. vesca].	22.59	394	236	15	65	434	284	632	4e-08	66.2
gp:CP002034_558	DNA topoisomerase [Lactobacillus salivarius CECT 5713]	24.75	295	180	8	166	452	69	329	4e-08	65.5
tr:A0A094DBX6_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY63936.1};	24.85	338	204	11	12	339	231	528	4e-08	65.9
tr:J8F644_BACCE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJQ96454.1};	26.62	154	103	4	309	457	1	149	4e-08	63.2
rs:XP_008599298	DNA topoisomerase [Beauveria bassiana ARSEF 2860].	24.78	335	205	12	10	335	227	523	4e-08	65.9
tr:C3JAB5_9PORP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	260	164	6	77	334	301	531	4e-08	66.2
sp:TOP3_YEAST	RecName: Full=DNA topoisomerase 3; EC=5.99.1.2; AltName: Full=DNA topoisomerase III;	25.27	368	202	12	42	380	296	619	4e-08	65.9
tr:A0A0C3CP21_HEBCY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.07	355	214	11	41	379	260	578	4e-08	65.9
tr:A0A0D4UY29_YEASX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.27	368	202	12	42	380	296	619	4e-08	65.9
rs:WP_017725890	hypothetical protein, partial [Bacillus ligniniphilus].	37.50	96	58	1	292	385	1	96	5e-08	63.5
tr:A0A0A2VXF1_BEABA	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:KGQ12576.1};	25.18	282	167	9	61	335	279	523	5e-08	65.9
rs:WP_034297059	DNA topoisomerase I [Alloscardovia omnicolens].	25.90	363	219	12	41	387	254	582	5e-08	65.9
tr:T1ZVG8_STRAP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AGU81557.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AGU81557.1};	25.08	315	185	12	93	396	244	518	5e-08	65.5
rs:WP_021584790	topoisomerase repeat protein, partial [Prevotella pleuritidis].	42.16	102	57	2	275	375	4	104	5e-08	63.5
rs:WP_029212697	DNA topoisomerase I [Arsenicicoccus bolidensis].	27.52	367	200	15	35	377	254	578	5e-08	65.9
rs:XP_004599449	PREDICTED: DNA topoisomerase 3-alpha [Ochotona princeps].	26.56	241	149	6	60	294	311	529	5e-08	65.9
tr:K2AAC1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	396	236	15	71	450	269	619	5e-08	65.9
rs:WP_026837499	DNA topoisomerase I [Gillisia sp. JM1].	24.92	305	177	10	36	334	218	476	5e-08	65.9
tr:I6F9D1_SHIBO	SubName: Full=DNA topoisomerase domain protein {ECO:0000313|EMBL:EIQ52873.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EIQ52873.1}; Flags: Fragment;	37.23	94	59	0	189	282	1	94	5e-08	61.6
rs:XP_004147675	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Cucumis sativus].	23.15	324	212	10	32	351	248	538	5e-08	65.9
tr:G7I5R0_MEDTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.23	310	193	9	61	350	404	688	5e-08	65.9
rs:WP_041783995	DNA topoisomerase [Streptococcus anginosus].	25.08	315	185	12	93	396	297	571	5e-08	65.5
rs:WP_015481981	DNA topoisomerase I [Polaribacter sp. MED152].	25.63	277	170	8	61	334	233	476	5e-08	65.9
tr:T1ZSD4_STRAP	SubName: Full=Putative DNA topoisomerase III {ECO:0000313|EMBL:AGU81119.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AGU81119.1};	25.08	315	185	12	93	396	266	540	5e-08	65.5
rs:WP_015753783	DNA topoisomerase I [Robiginitalea biformata].	25.67	261	159	6	77	334	249	477	5e-08	65.9
rs:XP_011651110	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Cucumis sativus].	23.15	324	212	10	32	351	188	478	5e-08	65.9
rs:WP_021627476	DNA topoisomerase I [Capnocytophaga sp. oral taxon 863].	25.48	314	185	9	35	334	198	476	5e-08	65.9
rs:XP_010650401	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Vitis vinifera].	24.15	294	176	11	65	351	290	543	5e-08	65.9
tr:F6I488_VITVI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.32	292	178	11	65	351	240	493	5e-08	65.9
tr:W4PP84_9BACE	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAE21572.1};	26.97	178	106	4	166	340	21	177	5e-08	65.5
rs:XP_010650402	PREDICTED: DNA topoisomerase 3-beta isoform X2 [Vitis vinifera].	24.32	292	178	11	65	351	225	478	5e-08	65.9
rs:WP_012777656	DNA topoisomerase I [Methylotenera mobilis].	23.17	410	256	15	60	449	246	616	5e-08	65.9
tr:A0A090RVV1_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL11482.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL11482.1};	36.67	90	55	1	140	227	21	110	5e-08	61.6
tr:W9GM03_9MICO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.21	294	174	9	77	356	298	565	5e-08	65.9
tr:W4U9X1_PROAA	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAE77339.1};	27.62	181	103	4	215	388	34	193	5e-08	63.5
tr:G0V1G7_TRYCI	SubName: Full=Putative uncharacterized protein TCIL3000_11_9530 {ECO:0000313|EMBL:CCC95488.1};	22.83	381	238	13	73	434	287	630	5e-08	65.9
rs:WP_013293439	DNA topoisomerase [Gallionella capsiferriformans].	23.39	342	182	12	73	399	281	557	5e-08	65.5
tr:U2DPA3_9CLOT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ERI81541.1};	34.56	136	77	4	293	425	1	127	5e-08	63.2
rs:XP_006412616	hypothetical protein EUTSA_v10024242mg [Eutrema salsugineum].	23.93	468	273	17	26	450	618	1045	6e-08	65.9
rs:WP_047034554	DNA topoisomerase I [Elizabethkingia meningoseptica].	26.40	322	189	10	36	350	217	497	6e-08	65.9
tr:X0QKL9_9LACO	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAF39155.1};	26.27	236	138	7	221	452	35	238	6e-08	64.3
rs:WP_009413402	DNA topoisomerase I [Capnocytophaga sp. oral taxon 326].	24.27	309	191	8	37	334	200	476	6e-08	65.5
tr:W1G3U3_ECOLX	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CDL40045.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDL40045.1};	27.95	161	91	3	187	347	6	141	6e-08	62.0
tr:R0MEX3_NOSB1	SubName: Full=DNA topoisomerase 3-alpha {ECO:0000313|EMBL:EOB11308.1};	24.27	342	213	11	40	374	199	501	6e-08	65.5
rs:WP_041224044	hypothetical protein, partial [Deferribacter desulfuricans].	25.44	287	142	14	69	328	252	493	6e-08	65.5
rs:XP_007158787	hypothetical protein PHAVU_002G181900g [Phaseolus vulgaris].	21.86	462	283	15	36	458	480	902	6e-08	65.9
rs:WP_024599854	hypothetical protein [Pseudoalteromonas haloplanktis].	38.46	78	48	0	36	113	251	328	6e-08	64.3
tr:A0A0C9XCQ7_9AGAR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.03	365	209	15	38	382	250	573	6e-08	65.9
rs:WP_021718458	MULTISPECIES: DNA topoisomerase [Firmicutes].	22.71	414	257	12	63	456	243	613	6e-08	65.5
rs:WP_018675058	DNA topoisomerase I [Riemerella columbina].	25.61	285	170	9	77	352	248	499	6e-08	65.5
rs:WP_032816953	DNA topoisomerase I, partial [Gardnerella vaginalis].	26.81	317	188	12	71	376	2	285	6e-08	64.7
sp:TOP3_DICDI	RecName: Full=DNA topoisomerase 3; EC=5.99.1.2; AltName: Full=DNA topoisomerase III;	25.09	283	173	8	73	351	322	569	6e-08	65.5
rs:WP_009495774	DNA topoisomerase I [Campylobacter showae].	23.53	357	220	14	47	385	223	544	6e-08	65.5
rs:WP_012504231	topoisomerase I [Candidatus Phytoplasma mali].	21.23	424	265	12	47	451	216	589	6e-08	65.5
rs:WP_008802992	DNA topoisomerase III [Fusobacterium nucleatum].	23.71	388	227	16	77	431	286	637	6e-08	65.5
rs:WP_020567233	hypothetical protein [Lewinella persica].	25.25	297	189	7	36	328	212	479	6e-08	65.5
rs:WP_033617862	hypothetical protein, partial [Lactobacillus plantarum].	44.62	65	36	0	277	341	3	67	6e-08	60.8
rs:WP_004421347	DNA topoisomerase I [Leptospira noguchii].	21.43	448	282	15	31	450	197	602	6e-08	65.5
rs:WP_024821701	DNA topoisomerase I [Aminobacterium mobile].	23.86	440	256	19	47	457	238	627	6e-08	65.5
rs:WP_032812965	DNA topoisomerase I, partial [Gardnerella vaginalis].	26.77	310	184	11	77	376	7	283	6e-08	65.5
rs:WP_014389293	DNA topoisomerase I [Flavobacterium indicum].	25.09	287	166	8	77	346	249	503	6e-08	65.5
rs:WP_023578429	DNA topoisomerase I [Flavobacterium limnosediminis].	27.38	263	151	9	77	334	249	476	6e-08	65.5
rs:WP_032515553	DNA topoisomerase I [Prochlorococcus marinus].	25.62	324	203	11	77	393	286	578	6e-08	65.5
tr:A0A0D0HY40_BACTM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	36.36	88	56	0	48	135	245	332	6e-08	64.3
tr:A0A0C2THH2_AMAMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.13	328	183	12	39	352	255	540	6e-08	65.5
rs:WP_047936826	DNA topoisomerase, partial [Enterococcus faecium].	32.12	165	103	4	52	212	131	290	6e-08	63.9
rs:XP_007766399	prokaryotic type I DNA topoisomerase [Coniophora puteana RWD-64-598 SS2].	24.66	365	216	12	43	392	261	581	6e-08	65.5
rs:WP_034055413	hypothetical protein, partial [Pseudomonas aeruginosa].	25.32	395	217	18	77	446	245	586	6e-08	65.1
rs:WP_013739712	DNA topoisomerase I [Sphaerochaeta coccoides].	25.08	323	201	9	77	387	281	574	6e-08	65.5
rs:WP_046438492	DNA topoisomerase III, partial [Ruminococcus sp. UNK.MGS-30].	41.38	87	50	1	37	123	227	312	6e-08	64.3
rs:WP_033703710	hypothetical protein [Bacillus thuringiensis].	39.19	74	45	0	160	233	2	75	6e-08	60.8
tr:A0A0A1WLU7_BACCU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.83	302	181	9	35	331	276	539	6e-08	65.1
rs:WP_031528031	DNA topoisomerase I [Dyadobacter crusticola].	27.41	270	162	9	68	335	242	479	6e-08	65.5
tr:A0A068Y8Q8_ECHMU	SubName: Full=DNA topoisomerase 3 beta 1 {ECO:0000313|EMBL:CDS39641.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDS39641.1};	23.06	438	272	15	40	453	283	679	6e-08	65.5
rs:WP_029169405	hypothetical protein [Clostridium botulinum].	29.57	186	105	9	293	454	1	184	6e-08	62.8
rs:WP_034719059	DNA topoisomerase I [Intrasporangium chromatireducens].	27.21	294	174	9	77	356	289	556	6e-08	65.5
rs:WP_034344989	hypothetical protein [Helicobacter trogontum].	20.71	396	243	12	15	385	190	539	7e-08	65.5
tr:K3WHB4_PYTUL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblProtists:PYU1_T004356};	23.08	351	222	10	40	377	261	576	7e-08	65.5
rs:WP_044232760	DNA topoisomerase I [Porphyromonas sp. COT-290 OH3588].	25.76	264	150	8	77	334	253	476	7e-08	65.5
rs:WP_015090086	DNA topoisomerase I [Bdellovibrio bacteriovorus].	23.36	274	175	6	77	344	294	538	7e-08	65.5
tr:N1J751_BLUG1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.47	318	188	11	40	347	264	542	7e-08	65.5
rs:WP_038984721	DNA topoisomerase I [Myroides odoratimimus].	28.08	260	153	8	77	334	249	476	7e-08	65.5
tr:A0A077EBF0_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.40	322	189	10	36	350	187	467	7e-08	65.5
rs:WP_040349776	DNA topoisomerase, partial [Anaerococcus tetradius].	33.88	121	73	2	280	398	1	116	7e-08	61.6
rs:WP_034888609	DNA topoisomerase I [Gillisia sp. Hel_I_29].	26.10	272	160	9	68	334	241	476	7e-08	65.5
rs:WP_025761525	DNA topoisomerase I [Dyadobacter tibetensis].	26.62	263	155	8	77	335	248	476	7e-08	65.5
rs:WP_007137737	DNA topoisomerase I [Flavobacterium frigoris].	27.00	263	152	8	77	334	249	476	7e-08	65.5
rs:WP_036118829	DNA topoisomerase I [Mangrovimonas yunxiaonensis].	25.38	264	155	8	77	334	249	476	7e-08	65.5
rs:WP_032838476	DNA topoisomerase I [Fusobacterium sp. CM1].	23.71	388	227	16	77	431	286	637	7e-08	65.5
rs:WP_019260527	DNA topoisomerase I [Gardnerella vaginalis].	25.61	328	195	12	42	354	259	552	7e-08	65.5
rs:WP_024568243	DNA topoisomerase I [Elizabethkingia anophelis].	26.40	322	189	10	36	350	217	497	7e-08	65.5
rs:XP_006450082	hypothetical protein CICLE_v10007345mg [Citrus clementina].	25.17	437	259	17	60	458	425	831	7e-08	65.5
rs:WP_033624195	DNA topoisomerase, partial [Enterococcus faecium].	31.52	165	104	4	52	212	264	423	7e-08	64.7
tr:A0A0D4U6R1_YEASX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.27	368	202	12	42	380	296	619	7e-08	65.1
rs:WP_035589535	DNA topoisomerase I [Elizabethkingia anophelis].	26.40	322	189	10	36	350	217	497	7e-08	65.5
rs:WP_009086613	MULTISPECIES: DNA topoisomerase I [Elizabethkingia].	26.40	322	189	10	36	350	217	497	7e-08	65.5
rs:WP_004569061	DNA topoisomerase I [Polaribacter irgensii].	26.82	261	155	9	77	334	249	476	7e-08	65.5
rs:WP_047937007	DNA topoisomerase, partial [Enterococcus faecium].	32.12	165	103	4	52	212	264	423	7e-08	64.7
rs:WP_002681710	DNA topoisomerase I [Capnocytophaga sputigena].	25.56	270	164	10	68	334	241	476	7e-08	65.5
rs:WP_046323449	DNA topoisomerase I [Bifidobacterium asteroides].	25.77	326	196	12	42	354	260	552	7e-08	65.5
tr:A0A0E0M300_ORYPU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.54	346	212	13	65	393	284	590	7e-08	65.5
tr:E0H2D5_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.12	165	103	4	52	212	264	423	7e-08	64.7
rs:WP_011520484	topoisomerase I [Candidatus Baumannia cicadellinicola].	23.69	363	220	14	77	425	273	592	8e-08	65.5
rs:WP_029739023	DNA topoisomerase, partial [Enterococcus faecalis].	32.12	165	103	4	52	212	264	423	8e-08	64.7
tr:Z2D976_PSEAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.94	405	224	19	77	454	84	435	8e-08	64.7
rs:WP_043120466	DNA topoisomerase I, partial [Propionibacterium acidifaciens].	25.40	378	212	14	33	377	240	580	8e-08	65.5
gp:CP010088_750	DNA topoisomerase family protein [Bacillus thuringiensis]	26.22	164	113	4	35	195	1	159	8e-08	62.0
rs:WP_016198248	DNA topoisomerase I [Elizabethkingia meningoseptica].	26.09	322	190	10	36	350	217	497	8e-08	65.1
tr:D3PEJ4_DEFDS	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:BAI81636.1};	26.13	287	140	15	69	328	252	493	8e-08	65.1
tr:F0WXN3_9STRA	RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};	24.65	353	214	12	40	377	289	604	8e-08	65.5
tr:F0WXN5_9STRA	RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};	24.65	353	214	12	40	377	289	604	8e-08	65.5
tr:A0A090Q0M1_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.87	331	199	10	20	334	183	476	8e-08	65.1
tr:V4QWD7_STRIN	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ESR08798.1}; Flags: Fragment;	30.54	167	89	5	165	331	44	183	8e-08	62.0
tr:F0WXN2_9STRA	RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};	24.65	353	214	12	40	377	289	604	8e-08	65.5
rs:WP_004113830	DNA topoisomerase I [Gardnerella vaginalis].	26.18	317	190	11	71	376	282	565	8e-08	65.1
rs:WP_037325674	DNA topoisomerase I [Anaerovibrio sp. RM50].	24.05	420	247	17	65	457	240	614	8e-08	65.1
rs:WP_004123146	DNA topoisomerase I [Gardnerella vaginalis].	26.81	317	188	12	71	376	282	565	8e-08	65.1
tr:K1U894_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC76189.1}; Flags: Fragment;	31.39	137	81	4	152	285	22	148	8e-08	61.6
rs:WP_020366069	hypothetical protein, partial [Staphylococcus epidermidis].	33.86	127	71	4	54	173	12	132	8e-08	61.6
rs:XP_001771420	predicted protein, partial [Physcomitrella patens].	25.95	370	215	16	37	379	225	562	8e-08	65.1
rs:WP_026718357	DNA topoisomerase I [Flavobacterium gelidilacus].	26.62	263	153	8	77	334	249	476	8e-08	65.1
rs:WP_021347695	DNA topoisomerase I [Elizabethkingia meningoseptica].	26.40	322	189	10	36	350	217	497	8e-08	65.1
tr:F0WXN9_9STRA	RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};	24.65	353	214	12	40	377	289	604	8e-08	65.5
tr:W1JVM1_9BRAD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.06	374	222	12	106	452	12	350	8e-08	65.1
rs:WP_010148231	DNA topoisomerase I [Serinicoccus profundi].	24.86	366	214	14	44	384	265	594	8e-08	65.1
rs:WP_006593989	DNA topoisomerase I [Kineosphaera limosa].	26.89	305	166	11	77	356	290	562	9e-08	65.1
rs:WP_026914641	DNA topoisomerase I [Gramella portivictoriae].	26.82	302	179	11	68	360	241	509	9e-08	65.1
rs:WP_004132171	DNA topoisomerase I [Gardnerella vaginalis].	26.81	317	188	12	71	376	282	565	9e-08	65.1
tr:F0WXN8_9STRA	RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};	24.65	353	214	12	40	377	289	604	9e-08	65.5
rs:WP_012185183	DNA topoisomerase [Caldivirga maquilingensis].	26.97	330	195	12	67	383	274	570	9e-08	64.7
rs:WP_047263941	DNA topoisomerase I [Candidatus Liberibacter africanus].	22.83	438	275	17	47	452	230	636	9e-08	65.1
rs:WP_006279550	DNA topoisomerase I, partial [Wolbachia endosymbiont of Muscidifurax uniraptor].	26.92	208	120	5	259	452	1	190	9e-08	64.3
tr:F0WXN7_9STRA	RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};	24.65	353	214	12	40	377	289	604	9e-08	65.5
tr:F0WXN1_9STRA	RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};	24.65	353	214	12	40	377	289	604	9e-08	65.5
tr:W5JGG5_ANODA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.02	430	266	16	18	424	235	622	9e-08	65.1
rs:WP_034901041	DNA topoisomerase I [Erythrobacter litoralis].	24.25	433	269	13	45	453	228	625	9e-08	65.1
tr:F0WXN4_9STRA	RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};	24.65	353	214	12	40	377	289	604	9e-08	65.5
tr:A0A0D8XUE2_DICVI	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:KJH48145.1};	26.57	271	162	8	85	352	552	788	9e-08	65.1
rs:WP_046312892	DNA topoisomerase I [Pontibacter korlensis].	24.61	317	193	8	33	334	195	480	9e-08	65.1
rs:WP_020301296	DNA topoisomerase I [Pseudomonas sp. CF150].	24.92	309	194	10	46	347	230	507	9e-08	64.7
tr:U2SE50_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.46	377	213	13	33	377	240	580	9e-08	65.1
tr:A0A0A9J692_ARUDO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.72	465	286	16	26	450	172	598	9e-08	65.1
tr:F0WXP0_9STRA	RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};	24.65	353	214	12	40	377	289	604	9e-08	65.5
rs:WP_015022536	DNA topoisomerase I [Bifidobacterium asteroides].	26.02	342	194	13	37	354	244	550	9e-08	65.1
rs:WP_020054580	hypothetical protein [alpha proteobacterium SCGC AAA015-N04].	23.06	451	262	18	41	452	224	628	9e-08	65.1
rs:WP_041874370	hypothetical protein, partial [Microgenomates bacterium SCGC AAA011-A19].	25.64	390	215	16	86	452	294	631	9e-08	64.7
tr:Q4T0Q4_TETNG	SubName: Full=Chromosome undetermined SCAF10893, whole genome shotgun sequence {ECO:0000313|EMBL:CAF93528.1}; Flags: Fragment;	22.77	303	178	9	168	453	21	284	9e-08	64.3
rs:WP_016795062	DNA topoisomerase, partial [Gardnerella vaginalis].	26.81	317	188	12	71	376	57	340	9e-08	64.7
rs:WP_023040405	DNA topoisomerase III [Fusobacterium nucleatum].	23.71	388	227	16	77	431	286	637	1e-07	65.1
tr:A0A0B7A9N8_9EUPU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.26	198	140	5	40	236	260	452	1e-07	64.3
tr:A0A068X7F0_HYMMI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.17	469	272	14	39	450	257	689	1e-07	65.1
tr:A0A061RPU1_9CHLO	SubName: Full=Dna topoisomerase i {ECO:0000313|EMBL:JAC74917.1}; Flags: Fragment;	26.05	334	187	14	155	454	49	356	1e-07	64.7
rs:WP_033960908	DNA topoisomerase I [Psychroserpens jangbogonensis].	26.54	260	157	8	77	334	249	476	1e-07	65.1
rs:WP_026813116	DNA topoisomerase I [Arenibacter certesii].	24.20	281	181	7	56	334	228	478	1e-07	64.7
rs:WP_047797887	DNA topoisomerase I [Pedobacter sp. BMA].	24.71	348	207	9	61	377	234	557	1e-07	65.1
rs:WP_038235709	DNA topoisomerase I [Zobellia uliginosa].	24.90	261	162	6	77	334	249	478	1e-07	64.7
rs:WP_044635299	DNA topoisomerase I [Mycoplasma dispar].	28.88	187	98	6	277	455	457	616	1e-07	64.7
tr:S4GKC5_GARVA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	29.94	157	85	3	220	376	125	256	1e-07	63.5
rs:WP_047927966	DNA topoisomerase, partial [Enterococcus faecium].	32.12	165	103	4	52	212	264	423	1e-07	64.3
tr:Q2PY64_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.67	300	192	6	36	334	211	477	1e-07	64.7
tr:F0WXN6_9STRA	RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};	24.65	353	214	12	40	377	289	604	1e-07	65.1
rs:WP_032641589	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	34.62	104	59	2	349	452	9	103	1e-07	61.2
rs:WP_024332001	DNA topoisomerase I [Actinomyces neuii].	27.94	315	178	13	77	372	293	577	1e-07	64.7
rs:XP_011623691	PREDICTED: DNA topoisomerase 3-beta [Amborella trichopoda].	23.08	312	199	10	44	351	263	537	1e-07	64.7
rs:XP_001877918	predicted protein [Laccaria bicolor S238N-H82].	25.07	351	213	12	38	376	250	562	1e-07	64.7
tr:A0A017SV25_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.04	460	248	18	61	452	246	667	1e-07	64.7
tr:V6TB61_GIAIN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESU36111.1};	22.38	362	219	13	61	387	277	611	1e-07	64.7
tr:J7RTA4_KAZNA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.44	320	194	10	56	357	297	583	1e-07	64.7
rs:WP_033617866	hypothetical protein, partial [Lactobacillus plantarum].	49.15	59	30	0	277	335	3	61	1e-07	60.1
rs:WP_048357088	MULTISPECIES: DNA topoisomerase I [unclassified Methylophilales].	24.24	396	242	16	77	452	263	620	1e-07	64.7
rs:XP_010227764	PREDICTED: DNA topoisomerase 3-alpha-like [Brachypodium distachyon].	21.77	464	287	14	26	450	96	522	1e-07	64.7
rs:XP_006601079	PREDICTED: DNA topoisomerase 3-alpha-like isoform X5 [Glycine max].	21.17	496	317	17	3	458	454	915	1e-07	64.7
rs:WP_031922918	DNA topoisomerase III, partial [Staphylococcus aureus].	26.58	158	105	2	35	186	227	379	1e-07	63.9
tr:A0A0B2PKG3_GLYSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.47	233	127	7	110	333	283	482	1e-07	64.3
rs:WP_013751171	DNA topoisomerase I [Dokdonia sp. 4H-3-7-5].	25.52	290	166	10	62	340	235	485	1e-07	64.7
rs:WP_044252169	hypothetical protein, partial [Chondromyces apiculatus].	23.04	460	248	18	61	452	240	661	1e-07	64.7
rs:WP_014850163	DNA topoisomerase I [Mycoplasma wenyonii].	23.27	404	252	11	67	450	259	624	1e-07	64.7
rs:WP_019975010	DNA topoisomerase I [Empedobacter brevis].	25.38	264	160	7	77	336	249	479	1e-07	64.7
rs:WP_027480580	DNA topoisomerase I [Deinococcus pimensis].	25.25	305	177	11	57	344	289	559	1e-07	64.7
rs:WP_012532572	type I DNA topoisomerase TopA [Rhodococcus equi].	25.65	347	211	13	69	403	274	585	1e-07	64.7
tr:M3CGZ0_LEPIR	SubName: Full=Topoisomerase DNA-binding C4 zinc finger domain protein {ECO:0000313|EMBL:EMF40649.1};	23.67	300	178	11	166	450	60	323	1e-07	63.5
rs:WP_044167350	DNA topoisomerase III, partial [Staphylococcus aureus].	26.58	158	105	2	35	186	227	379	1e-07	63.9
tr:A0A024GV12_9STRA	SubName: Full=Albugo candida WGS project CAIX00000000 data, strain Ac Nc2, contig AcNc2_CONTIG_579_length_13152 {ECO:0000313|EMBL:CCI50570.1};	23.40	329	205	11	40	357	261	553	1e-07	64.7
tr:S4G7C1_GARVA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	29.94	157	85	3	220	376	125	256	1e-07	63.5
rs:WP_003636317	hypothetical protein, partial [Lactobacillus hilgardii].	32.84	134	75	5	101	227	3	128	1e-07	60.8
rs:XP_006601076	PREDICTED: DNA topoisomerase 3-alpha-like isoform X2 [Glycine max].	21.17	496	317	17	3	458	454	915	1e-07	64.7
rs:WP_004445466	DNA topoisomerase I [Leptospira noguchii].	21.83	449	279	15	31	450	197	602	1e-07	64.3
rs:WP_033627266	DNA topoisomerase, partial [Enterococcus faecium].	42.68	82	44	1	284	365	2	80	1e-07	62.0
rs:WP_035685277	DNA topoisomerase I [Flavobacterium reichenbachii].	26.62	263	153	8	77	334	249	476	1e-07	64.7
rs:WP_013852723	DNA topoisomerase I [Erysipelothrix rhusiopathiae].	22.13	479	271	13	40	455	218	657	1e-07	64.3
rs:WP_022100949	DNA topoisomerase I [Prevotella sp. CAG:5226].	23.75	299	192	6	47	338	222	491	1e-07	64.3
rs:XP_007362084	prokaryotic type I DNA topoisomerase, partial [Dichomitus squalens LYAD-421 SS1].	23.26	387	242	12	31	396	244	596	1e-07	64.7
tr:X1MFQ5_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S04839 {ECO:0000313|EMBL:GAI30108.1};	26.92	234	133	8	227	454	1	202	1e-07	62.4
tr:T1BI43_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD53810.1}; Flags: Fragment;	41.18	85	49	1	45	129	301	384	1e-07	63.5
rs:WP_023971651	hypothetical protein, partial [Salmonella enterica].	41.03	78	46	0	308	385	1	78	1e-07	60.8
tr:W0DWL7_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.77	291	172	10	61	347	231	481	1e-07	64.3
rs:WP_010518278	DNA topoisomerase I [Mesoflavibacter zeaxanthinifaciens].	26.15	260	160	7	77	334	249	478	1e-07	64.3
rs:WP_032448652	DNA topoisomerase III, partial [Klebsiella pneumoniae].	27.73	119	73	3	343	459	28	135	1e-07	62.0
tr:A0A059LMF1_9CHLO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.71	315	182	10	49	353	289	561	1e-07	64.3
rs:XP_006601078	PREDICTED: DNA topoisomerase 3-alpha-like isoform X4 [Glycine max].	21.31	488	310	17	11	458	460	913	1e-07	64.7
rs:WP_033562926	DNA topoisomerase I [Sphingobacteriaceae bacterium DW12].	24.76	311	192	7	29	335	212	484	1e-07	64.3
tr:A0A094HBG3_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFZ12247.1};	23.58	335	212	10	12	339	253	550	1e-07	64.3
tr:A0A094FE55_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY89129.1};	23.58	335	212	10	12	339	253	550	1e-07	64.3
rs:WP_004450175	DNA topoisomerase I [Leptospira noguchii].	21.83	449	279	15	31	450	197	602	1e-07	64.3
rs:WP_020760618	DNA topoisomerase, partial [Gardnerella vaginalis].	26.13	310	186	10	77	376	6	282	1e-07	63.5
rs:XP_001614250	DNA topoisomerase III alpha [Plasmodium vivax Sal-1].	24.24	330	211	9	64	385	330	628	1e-07	64.3
tr:A0A0F4ZCB9_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KKA28194.1};	25.17	294	168	10	53	335	273	525	1e-07	64.3
rs:WP_034706710	DNA topoisomerase, partial [Enterococcus gallinarum].	31.52	165	104	4	52	212	264	423	1e-07	63.5
rs:WP_018202630	hypothetical protein, partial [Parcubacteria bacterium SCGC AAA011-J21].	22.70	348	216	11	48	378	1	312	2e-07	63.9
tr:A0A094DUA8_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY69864.1};	24.02	333	213	9	12	339	231	528	2e-07	64.3
rs:XP_007864007	prokaryotic type I DNA topoisomerase [Gloeophyllum trabeum ATCC 11539].	24.40	336	195	11	39	357	260	553	2e-07	64.3
rs:WP_037358086	DNA topoisomerase I [Selenomonas sp. oral taxon 892].	22.71	436	277	12	41	457	245	639	2e-07	64.3
tr:A0A074WEW7_9PEZI	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:KEQ61046.1};	25.18	274	162	7	73	339	302	539	2e-07	64.3
rs:WP_010230372	DNA topoisomerase I [Gillisia marina].	24.92	301	182	10	36	334	218	476	2e-07	64.3
tr:A0A0C3EM39_9HOMO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.91	293	173	10	74	357	294	548	2e-07	63.9
rs:WP_048055657	DNA topoisomerase I, partial [Methanotorris igneus].	26.43	227	136	8	77	295	276	479	2e-07	63.9
tr:U2KLI8_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.71	436	277	12	41	457	259	653	2e-07	64.3
rs:WP_025914261	DNA topoisomerase I [Prochlorococcus sp. scB245a_520K10].	25.84	356	210	15	48	393	267	578	2e-07	64.3
tr:A0A066W1D5_9BASI	SubName: Full=Prokaryotic type I DNA topoisomerase {ECO:0000313|EMBL:KDN47556.1};	25.37	335	197	11	39	357	269	566	2e-07	64.3
rs:WP_024626956	DNA topoisomerase I [Bifidobacterium sp. A11].	25.66	343	207	12	25	354	243	550	2e-07	64.3
rs:WP_010252523	DNA topoisomerase I [Myroides injenensis].	27.69	260	154	8	77	334	249	476	2e-07	64.3
rs:WP_010744379	hypothetical protein [Enterococcus raffinosus].	35.85	106	66	1	289	392	14	119	2e-07	60.8
rs:WP_011900829	DNA topoisomerase [Pyrobaculum arsenaticum].	23.93	326	205	9	59	374	261	553	2e-07	63.9
rs:XP_010669509	PREDICTED: uncharacterized protein LOC104886724 isoform X2 [Beta vulgaris subsp. vulgaris].	24.12	427	252	15	65	450	415	810	2e-07	64.3
rs:WP_013349813	DNA topoisomerase I [Arthrobacter arilaitensis].	24.77	327	207	10	42	356	259	558	2e-07	64.3
rs:WP_038033385	MULTISPECIES: DNA topoisomerase I [Thermotoga].	24.38	320	189	10	74	377	242	524	2e-07	63.9
rs:XP_003602653	DNA topoisomerase [Medicago truncatula].	24.63	341	201	12	39	351	265	577	2e-07	63.9
tr:L2Q590_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELB49113.1};	42.68	82	44	1	284	365	5	83	2e-07	62.0
rs:WP_004124073	DNA topoisomerase I [Gardnerella vaginalis].	25.55	317	192	10	71	376	282	565	2e-07	64.3
rs:WP_013767752	DNA topoisomerase I [Haliscomenobacter hydrossis].	25.97	258	151	7	77	328	253	476	2e-07	64.3
rs:WP_003773150	DNA topoisomerase I [Erysipelothrix rhusiopathiae].	22.13	479	271	13	40	455	218	657	2e-07	63.9
rs:WP_025606038	DNA topoisomerase I [Pontibacter actiniarum].	25.08	315	194	7	33	334	195	480	2e-07	63.9
rs:WP_041483233	hypothetical protein, partial [Thioalkalimicrobium aerophilum].	25.77	291	172	10	61	347	231	481	2e-07	63.5
rs:WP_006266880	DNA topoisomerase I [Myroides odoratimimus].	27.69	260	154	8	77	334	249	476	2e-07	63.9
rs:WP_017650440	hypothetical protein, partial [Streptococcus agalactiae].	26.40	197	117	6	260	452	2	174	2e-07	62.0
rs:WP_026730539	DNA topoisomerase I [Flavobacterium denitrificans].	25.77	260	159	7	77	334	249	476	2e-07	63.9
rs:WP_009851878	DNA topoisomerase I [beta proteobacterium KB13].	23.99	396	243	16	77	452	263	620	2e-07	63.9
rs:WP_006259653	DNA topoisomerase I [Myroides odoratimimus].	27.69	260	154	8	77	334	249	476	2e-07	63.9
rs:WP_032819214	DNA topoisomerase I, partial [Gardnerella vaginalis].	25.87	317	191	11	71	376	4	287	2e-07	63.9
rs:WP_027880536	DNA topoisomerase I [Mesoflavibacter zeaxanthinifaciens].	25.38	264	155	9	77	334	249	476	2e-07	63.9
rs:WP_012194987	DNA topoisomerase I [Prochlorococcus marinus].	23.51	353	225	11	30	370	236	555	2e-07	63.9
rs:WP_006264644	DNA topoisomerase I [Myroides odoratimimus].	27.69	260	154	8	77	334	249	476	2e-07	63.9
tr:A0A094FUR7_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY92408.1};	24.85	338	204	11	12	339	231	528	2e-07	64.3
rs:WP_016650340	DNA topoisomerase I [Myroides odoratimimus].	27.69	260	154	8	77	334	249	476	2e-07	63.9
rs:WP_047778525	DNA topoisomerase I [Flavobacterium sp. ABG].	26.62	263	153	8	77	334	249	476	2e-07	63.9
rs:WP_021091905	DNA topoisomerase I [Campylobacter concisus].	23.25	357	221	14	47	385	223	544	2e-07	63.9
rs:WP_041894333	DNA topoisomerase I [Myroides profundi].	27.69	260	154	8	77	334	249	476	2e-07	63.9
rs:WP_016583080	topoisomerase I, partial [Yersinia pestis].	25.10	259	155	8	195	446	1	227	2e-07	63.5
tr:H3CHY5_TETNG	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTNIP00000007863};	22.77	303	178	9	168	453	342	605	2e-07	63.9
rs:WP_025124920	DNA topoisomerase I [Myroides odoratimimus].	27.69	260	154	8	77	334	249	476	2e-07	63.9
tr:A0A022QQM7_ERYGU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EYU30256.1};	22.76	457	284	15	34	458	410	829	2e-07	63.9
rs:WP_039328605	DNA topoisomerase I [Myroides sp. A21].	27.69	260	154	8	77	334	249	476	2e-07	63.9
rs:WP_033630456	DNA topoisomerase, partial [Enterococcus faecium].	43.21	81	43	1	285	365	1	78	2e-07	61.6
rs:WP_020145169	DNA topoisomerase I [Terracoccus sp. 273MFTsu3.1].	27.88	312	172	11	66	356	277	556	2e-07	63.9
rs:WP_032840374	DNA topoisomerase I, partial [Gardnerella vaginalis].	25.87	317	191	11	71	376	9	292	2e-07	63.9
tr:A0A0C3NN51_PHLGI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.16	327	204	10	39	357	258	548	2e-07	63.5
rs:WP_023491655	DNA topoisomerase 1 [Serratia sp. DD3].	24.30	321	197	10	77	386	284	569	2e-07	63.9
rs:WP_018694136	hypothetical protein [Algicola sagamiensis].	24.32	370	211	17	90	440	257	576	2e-07	63.9
rs:WP_036592880	DNA topoisomerase III, partial [Paenibacillus sophorae].	37.18	78	49	0	38	115	233	310	2e-07	62.8
rs:XP_010669508	PREDICTED: uncharacterized protein LOC104886724 isoform X1 [Beta vulgaris subsp. vulgaris].	24.14	435	258	15	65	458	647	1050	2e-07	63.9
rs:WP_025633988	hypothetical protein [Vibrio parahaemolyticus].	25.75	334	170	13	82	371	345	644	2e-07	63.9
tr:K0WJ72_9RHIZ	SubName: Full=DNA topoisomerase I subunit omega {ECO:0000313|EMBL:EJZ23264.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EJZ23264.1}; Flags: Fragment;	24.92	313	186	11	166	452	40	329	2e-07	63.5
tr:T0SFG4_LACFE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.32	155	89	6	56	201	73	217	2e-07	61.2
rs:WP_013769649	DNA topoisomerase I [Cellulomonas fimi].	26.61	357	199	13	35	356	239	567	2e-07	63.9
tr:A0A024GUU9_9STRA	SubName: Full=Albugo candida WGS project CAIX00000000 data, strain Ac Nc2, contig AcNc2_CONTIG_579_length_13152 {ECO:0000313|EMBL:CCI50569.1};	23.40	329	205	11	40	357	261	553	2e-07	63.5
rs:WP_040752684	DNA topoisomerase I [Tetrasphaera elongata].	23.81	357	217	10	42	376	256	579	2e-07	63.9
rs:WP_038892878	DNA topoisomerase III, partial [Vibrio campbellii].	27.73	119	72	3	343	459	4	110	2e-07	60.5
rs:WP_007351674	DNA topoisomerase I [Marinobacter sp. ELB17].	23.50	434	258	18	77	458	250	661	2e-07	63.5
rs:WP_014781568	DNA topoisomerase I [Aequorivita sublithincola].	25.10	263	160	7	77	334	249	479	2e-07	63.5
rs:WP_020032014	hypothetical protein [gamma proteobacterium SCGC AAA300-D14].	22.59	394	256	11	40	424	263	616	2e-07	63.5
rs:WP_006989665	DNA topoisomerase I [Gillisia limnaea].	25.45	275	158	9	68	334	241	476	2e-07	63.5
rs:WP_045935848	DNA topoisomerase I [Bifidobacterium asteroides].	25.77	326	194	12	42	354	260	550	2e-07	63.5
rs:WP_032842622	DNA topoisomerase III, partial [Gardnerella vaginalis].	27.81	151	92	2	140	289	3	137	2e-07	60.1
rs:WP_013930323	DNA topoisomerase I [Runella slithyformis].	26.22	267	161	8	77	340	252	485	2e-07	63.5
rs:WP_035428063	MULTISPECIES: topoisomerase I, partial [Lactobacillus].	30.32	155	89	6	56	201	100	244	2e-07	61.6
rs:WP_036897368	DNA topoisomerase I [Prochlorococcus marinus].	25.08	323	206	10	77	393	286	578	2e-07	63.5
rs:WP_022809233	DNA topoisomerase I [Aminicenantes bacterium SCGC AAA252-K06].	22.60	292	182	9	166	449	344	599	3e-07	63.5
rs:WP_038891427	DNA topoisomerase III, partial [Vibrio campbellii].	27.73	119	72	3	343	459	4	110	3e-07	60.5
tr:N0E0E4_9MICO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.81	357	217	10	42	376	259	582	3e-07	63.5
rs:WP_025767074	hypothetical protein [Vibrio parahaemolyticus].	26.73	318	187	11	82	371	345	644	3e-07	63.5
rs:WP_015639701	DNA topoisomerase, partial [Lactobacillus plantarum].	30.32	155	89	6	56	201	109	253	3e-07	61.6
rs:XP_010548523	PREDICTED: uncharacterized protein LOC104819919 [Tarenaya hassleriana].	23.43	431	265	13	65	458	569	971	3e-07	63.5
tr:M1BDQ9_SOLTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.02	246	150	7	107	351	9	223	3e-07	63.2
tr:A0A0D3A2X7_BRAOL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.61	482	287	16	26	458	605	1049	3e-07	63.5
rs:WP_013189669	type I DNA topoisomerase TopA [Rhodococcus equi].	25.66	339	204	13	79	403	281	585	3e-07	63.5
rs:WP_031454641	DNA topoisomerase I [Flavobacterium chungangense].	26.24	263	154	8	77	334	249	476	3e-07	63.5
rs:WP_040054012	DNA topoisomerase I, partial [Candidatus Arthromitus sp. SFB-4].	23.46	324	200	8	77	385	254	544	3e-07	63.2
rs:WP_016820164	DNA topoisomerase, partial [Gardnerella vaginalis].	25.87	317	191	11	71	376	63	346	3e-07	63.5
tr:W4LDQ7_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.75	80	53	0	59	138	251	330	3e-07	62.4
rs:XP_012450480	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Gossypium raimondii].	22.66	428	271	12	65	458	572	973	3e-07	63.5
rs:XP_001747315	hypothetical protein [Monosiga brevicollis MX1].	22.02	377	236	14	17	382	204	533	3e-07	63.5
rs:WP_009994256	DNA topoisomerase I [Gardnerella vaginalis].	25.55	317	192	10	71	376	282	565	3e-07	63.5
rs:WP_014554820	DNA topoisomerase I [Gardnerella vaginalis].	25.55	317	192	10	71	376	282	565	3e-07	63.5
rs:XP_012450479	PREDICTED: uncharacterized protein LOC105773277 isoform X1 [Gossypium raimondii].	22.66	428	271	12	65	458	572	973	3e-07	63.5
rs:XP_007380820	prokaryotic type I DNA topoisomerase [Punctularia strigosozonata HHB-11173 SS5].	24.41	299	176	10	73	357	283	545	3e-07	63.2
rs:WP_013798929	DNA topoisomerase I [Methanotorris igneus].	26.55	226	135	8	77	294	276	478	3e-07	63.5
rs:WP_021897169	DNA topoisomerase TopA [Prevotella sp. CAG:924].	26.07	257	153	8	86	334	271	498	3e-07	63.5
rs:WP_013399414	DNA topoisomerase I [Gardnerella vaginalis].	25.55	317	192	10	71	376	294	577	3e-07	63.5
rs:WP_044428451	hypothetical protein [Mannheimia haemolytica].	40.85	71	42	0	293	363	1	71	3e-07	58.5
tr:A0A0E0IGT3_ORYNI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.86	242	159	7	39	275	322	550	3e-07	63.5
rs:WP_014127330	DNA topoisomerase [Thermoproteus tenax].	24.33	300	190	7	59	354	265	531	3e-07	63.2
rs:WP_009409628	DNA topoisomerase I [Actinomyces sp. oral taxon 448].	26.45	344	191	12	45	356	279	592	3e-07	63.5
tr:A0A0E9E408_CHLTH	SubName: Full=DNA topoisomerase I-fused to SWI domain {ECO:0000313|EMBL:CRH64738.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CRH64738.1};	25.55	317	192	10	71	376	282	565	3e-07	63.5
rs:XP_010093883	DNA topoisomerase 3-beta-1 [Morus notabilis].	22.22	387	246	13	65	434	59	407	3e-07	63.2
rs:WP_028481868	DNA topoisomerase I [Nesiotobacter exalbescens].	22.67	419	257	11	61	446	244	628	3e-07	63.5
rs:WP_046201098	DNA topoisomerase I [Candidatus Pantoea carbekii].	25.18	282	172	10	77	354	281	527	3e-07	63.5
rs:WP_032836650	DNA topoisomerase I, partial [Gardnerella vaginalis].	25.55	317	192	10	71	376	14	297	3e-07	63.2
rs:WP_020759764	DNA topoisomerase I [Gardnerella vaginalis].	25.55	317	192	10	71	376	282	565	3e-07	63.5
rs:WP_004806974	MULTISPECIES: DNA topoisomerase I [Actinomycetaceae].	27.44	317	177	14	77	372	293	577	3e-07	63.5
rs:WP_010613785	DNA topoisomerase I, partial [Actinomyces oris].	26.22	370	201	16	44	377	2	335	3e-07	62.4
rs:WP_011620028	DNA topoisomerase I [Synechococcus sp. CC9311].	22.93	375	238	9	37	389	246	591	3e-07	63.2
rs:WP_004112809	DNA topoisomerase I [Gardnerella vaginalis].	25.55	317	192	10	71	376	282	565	3e-07	63.2
rs:WP_004118179	DNA topoisomerase I [Gardnerella vaginalis].	25.55	317	192	10	71	376	282	565	3e-07	63.2
rs:WP_033445913	DNA topoisomerase I, partial [Succinivibrionaceae bacterium WG-1].	24.92	305	172	10	77	376	4	256	3e-07	63.2
tr:W4LYF2_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.75	80	53	0	59	138	256	335	3e-07	62.4
rs:WP_028848545	DNA topoisomerase I [Thermocrispum agreste].	25.86	290	169	10	77	351	303	561	3e-07	63.2
rs:WP_022564615	DNA topoisomerase I [Candidatus Pantoea carbekii].	25.18	282	172	10	77	354	281	527	3e-07	63.2
tr:V7Z562_LACPN	RecName: Full=DNA topoisomerase I, plasmid {ECO:0000256|SAAS:SAAS00003555}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	23.28	305	181	10	77	366	297	563	3e-07	62.8
tr:G1VGY7_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGW46163.1};	30.83	133	79	4	74	206	276	395	3e-07	62.8
rs:WP_015333594	DNA topoisomerase I [Fibrella aestuarina].	26.95	282	163	8	68	339	243	491	3e-07	63.2
rs:WP_011403873	DNA topoisomerase I [Salinibacter ruber].	25.94	320	193	10	41	344	254	545	3e-07	63.2
tr:A0A0B8QHJ9_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.36	258	148	10	77	329	290	510	3e-07	62.8
tr:A6D7J0_9VIBR	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EDL51415.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EDL51415.1};	26.12	291	172	11	166	446	22	279	3e-07	62.0
rs:WP_027413100	DNA topoisomerase I [Aquimarina muelleri].	26.01	273	159	10	68	334	241	476	3e-07	63.2
rs:WP_038821516	hypothetical protein, partial [Pseudomonas syringae].	43.08	65	37	0	159	223	2	66	3e-07	58.2
rs:WP_033521565	DNA topoisomerase I [Bifidobacterium bohemicum].	25.07	339	205	11	31	354	245	549	3e-07	63.2
tr:A0A0E0B045_9ORYZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.83	246	162	7	39	279	209	441	4e-07	63.2
rs:XP_011104558	top3p [Saccharomyces arboricola H-6].	24.62	325	188	8	56	357	300	590	4e-07	62.8
rs:WP_036450838	DNA topoisomerase I [Mycoplasma opalescens].	23.71	426	242	15	58	452	223	596	4e-07	62.8
rs:WP_031410710	hypothetical protein [Vibrio parahaemolyticus].	54.55	44	20	0	416	459	44	87	4e-07	58.9
rs:WP_038332922	DNA topoisomerase I [Empedobacter falsenii].	25.48	263	161	6	77	336	249	479	4e-07	63.2
rs:WP_014451788	DNA topoisomerase I [Fervidobacterium pennivorans].	24.23	326	194	11	70	377	272	562	4e-07	62.8
rs:WP_026451379	DNA topoisomerase I [Aequorivita capsosiphonis].	25.10	263	160	7	77	334	249	479	4e-07	63.2
rs:XP_006285818	hypothetical protein CARUB_v10007294mg [Capsella rubella].	23.50	434	253	15	61	450	726	1124	4e-07	63.2
rs:WP_032517561	DNA topoisomerase I [Prochlorococcus marinus].	25.00	324	205	11	77	393	286	578	4e-07	63.2
rs:WP_046492712	DNA topoisomerase I [Flavobacteriaceae bacterium ASP10-09a].	24.83	302	181	9	36	334	218	476	4e-07	63.2
tr:A0A094A6C6_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY22823.1};	23.62	309	193	9	37	339	257	528	4e-07	63.2
rs:XP_002622287	DNA topoisomerase III [Blastomyces dermatitidis SLH14081].	25.00	276	158	8	73	339	276	511	4e-07	62.8
tr:X1JUR8_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S21763 {ECO:0000313|EMBL:GAH82004.1}; Flags: Fragment;	26.12	268	142	8	211	456	3	236	4e-07	60.8
rs:WP_019261354	DNA topoisomerase I [Gardnerella vaginalis].	25.87	317	191	11	71	376	282	565	4e-07	63.2
tr:W6KVP2_9TRYP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.28	305	198	6	82	380	295	569	4e-07	63.2
rs:WP_038051617	DNA topoisomerase I [Thermotoga sp. Mc24].	24.06	320	190	10	74	377	242	524	4e-07	62.8
rs:XP_001388324	DNA topoisomerase III beta-1 [Cryptosporidium parvum Iowa II].	20.00	365	255	9	18	375	234	568	4e-07	63.2
rs:WP_022211948	DNA topoisomerase [Clostridium sp. CAG:265].	30.83	133	82	4	40	169	256	381	4e-07	62.4
rs:WP_042775697	hypothetical protein, partial [Vibrio parahaemolyticus].	48.00	50	26	0	410	459	41	90	4e-07	58.9
tr:A0A0C2FHF5_9BILA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIH48005.1}; Flags: Fragment;	28.57	168	92	4	167	334	18	157	4e-07	59.7
tr:U4L9N6_PYROM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.37	292	165	11	60	339	285	538	4e-07	62.8
rs:WP_020539370	hypothetical protein [Lewinella cohaerens].	25.88	255	156	7	77	328	253	477	4e-07	62.8
rs:WP_013146985	DNA topoisomerase I [Methylotenera versatilis].	25.15	338	200	11	60	377	246	550	4e-07	62.8
tr:A0A0E0CVM3_9ORYZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.83	246	162	7	39	279	271	503	4e-07	62.8
tr:B7C992_9FIRM	SubName: Full=Topoisomerase DNA-binding C4 zinc finger domain protein {ECO:0000313|EMBL:EEC90669.1};	32.12	137	81	4	311	445	14	140	4e-07	60.5
rs:WP_025443402	DNA topoisomerase I [Borrelia miyamotoi].	23.51	302	187	10	70	366	282	544	4e-07	62.8
tr:A0A0E0E8K2_9ORYZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.54	346	212	13	65	393	284	590	4e-07	62.8
rs:XP_006601080	PREDICTED: DNA topoisomerase 3-alpha-like isoform X6 [Glycine max].	22.00	350	224	11	11	339	462	783	4e-07	62.8
tr:C5GWY5_AJEDR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.00	276	158	8	73	339	301	536	4e-07	62.8
rs:XP_002436546	hypothetical protein SORBIDRAFT_10g004493, partial [Sorghum bicolor].	21.74	460	292	15	26	450	530	956	4e-07	62.8
rs:WP_019126802	hypothetical protein, partial [Actinomyces sp. ph3].	25.60	168	105	2	222	386	13	163	4e-07	62.4
tr:A0A0F4XCG3_HANUV	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:KKA03654.1};	23.75	299	192	9	86	369	345	622	5e-07	62.8
rs:WP_007657593	DNA topoisomerase I [Pontibacter sp. BAB1700].	23.71	291	189	6	47	334	218	478	5e-07	62.8
tr:W4TTK9_PROAA	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAE71728.1};	27.62	181	103	4	215	388	34	193	5e-07	62.4
gp:AC104428_4	Putative DNA topoisomerase III [Oryza sativa Japonica Group]	26.83	246	162	7	39	279	368	600	5e-07	62.8
tr:U6S6G2_GARVA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.66	157	87	2	220	376	125	256	5e-07	62.8
rs:XP_010943344	PREDICTED: uncharacterized protein LOC105061088 [Elaeis guineensis].	21.35	445	276	15	47	450	540	951	5e-07	62.8
tr:G9ZIQ2_9GAMM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHM51401.1}; Flags: Fragment;	29.71	138	75	3	220	354	53	171	5e-07	59.7
tr:B8ANX5_ORYSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.83	246	162	7	39	279	368	600	5e-07	62.8
rs:WP_036489275	DNA topoisomerase I, partial [Myxosarcina sp. GI1].	24.00	375	236	11	74	438	260	595	5e-07	62.4
tr:A5IKG3_THEP1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00003390}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.06	320	190	10	74	377	242	524	5e-07	62.4
tr:A0A0D7AMB2_9AGAR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.72	352	215	11	41	378	259	574	5e-07	62.4
rs:WP_031655094	hypothetical protein, partial [Pseudomonas aeruginosa].	24.81	395	219	18	77	446	245	586	5e-07	62.4
rs:WP_014264447	DNA topoisomerase [Granulicella mallensis].	21.55	478	272	19	34	446	227	666	5e-07	62.8
rs:WP_041654938	DNA topoisomerase I [Arcobacter sp. L].	24.38	320	193	10	61	358	235	527	5e-07	62.4
tr:T1ABF9_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EQD38224.1}; Flags: Fragment;	30.33	244	128	13	66	287	254	477	5e-07	62.0
tr:G2HS89_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.38	320	193	10	61	358	209	501	5e-07	62.4
rs:WP_047265411	DNA topoisomerase I [Marinitoga sp. 1155].	24.93	353	205	13	61	392	239	552	6e-07	62.4
tr:F9P671_STRCV	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	23.31	266	158	8	39	284	208	447	6e-07	62.0
tr:A0A0E0NQ41_ORYRU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.83	246	162	7	39	279	270	502	6e-07	62.4
rs:WP_016121531	DNA topoisomerase 3, partial [Bacillus cereus].	40.00	70	42	0	48	117	245	314	6e-07	61.2
tr:A0A0D9Z2H4_9ORYZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.86	242	159	7	39	275	222	450	6e-07	62.4
rs:WP_018142403	hypothetical protein [Alloscardovia criceti].	25.92	355	213	13	41	377	253	575	6e-07	62.4
tr:A0A0D9Z2H5_9ORYZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.86	242	159	7	39	275	214	442	6e-07	62.4
rs:WP_025894079	DNA topoisomerase I, partial [Prochlorococcus sp. scB243_497J18].	28.79	257	146	14	48	294	240	469	6e-07	62.0
tr:A0A0E0GH86_ORYNI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.86	242	159	7	39	275	271	499	6e-07	62.4
tr:K1RYJ4_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC48294.1}; Flags: Fragment;	35.90	78	50	0	59	136	120	197	6e-07	59.7
rs:WP_026935201	DNA topoisomerase I [Gramella echinicola].	27.21	272	154	12	70	334	242	476	6e-07	62.4
rs:WP_034073375	hypothetical protein, partial [Pseudomonas aeruginosa].	24.81	395	219	18	77	446	245	586	6e-07	62.4
rs:WP_011181594	DNA topoisomerase I, partial [Bacillus thuringiensis].	26.22	164	113	4	35	195	178	336	6e-07	61.6
tr:F6JJ45_DROSI	SubName: Full=CG3458 {ECO:0000313|EMBL:ADG51428.1}; Flags: Fragment;	26.67	210	121	8	167	371	44	225	6e-07	60.1
rs:WP_012896210	DNA topoisomerase I [Thermotoga naphthophila].	24.06	320	190	10	74	377	242	524	6e-07	62.4
tr:B9FBH7_ORYSJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.83	246	162	7	39	279	368	600	6e-07	62.4
rs:WP_031757110	hypothetical protein, partial [Pseudomonas aeruginosa].	24.81	395	219	18	77	446	245	586	6e-07	62.0
tr:A0A084VTN2_9DIPT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.30	435	269	16	40	453	259	645	6e-07	62.4
tr:U5SB31_9LACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.70	114	75	2	56	169	263	372	6e-07	61.6
rs:WP_032518605	DNA topoisomerase I [Prochlorococcus marinus].	25.00	324	205	11	77	393	286	578	6e-07	62.4
rs:WP_036735945	DNA topoisomerase I, partial [Peptococcaceae bacterium SCADC1_2_3].	27.87	183	108	5	278	457	11	172	6e-07	60.1
rs:WP_043945782	DNA topoisomerase III, partial [Carnobacterium sp. WN1359].	30.70	114	75	2	56	169	260	369	6e-07	61.6
rs:WP_048153737	DNA topoisomerase [Thermoproteus sp. AZ2].	25.00	300	183	9	86	377	292	557	6e-07	62.0
rs:WP_016832197	DNA topoisomerase, partial [Gardnerella vaginalis].	28.66	157	87	2	220	376	136	267	6e-07	62.0
rs:XP_010257889	PREDICTED: DNA topoisomerase 3-alpha [Nelumbo nucifera].	21.68	452	286	15	34	450	638	1056	6e-07	62.4
tr:A0A024VL13_PLAFA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETW29414.1}; Flags: Fragment;	22.69	335	196	11	37	353	4	293	7e-07	61.2
rs:WP_038526951	DNA topoisomerase I [Formosa agariphila].	25.76	264	154	9	77	334	249	476	7e-07	62.4
rs:WP_044109241	DNA topoisomerase I [Acinetobacter sp. MII].	23.02	443	268	19	42	455	226	624	7e-07	62.4
tr:Q9JJ62_MOUSE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.30	214	139	7	25	228	247	447	7e-07	61.6
tr:W4J001_PLAFP	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETW55613.1};	22.42	397	230	14	37	400	346	697	7e-07	62.0
rs:XP_011094466	PREDICTED: uncharacterized protein LOC105174160 isoform X2 [Sesamum indicum].	22.09	430	279	10	61	458	599	1004	7e-07	62.4
tr:A0A024V2K8_PLAFA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETW16689.1};	22.42	397	230	14	37	400	49	400	7e-07	61.6
rs:WP_044432270	DNA topoisomerase I [Acinetobacter pittii].	23.02	443	268	19	42	455	226	624	7e-07	62.4
rs:XP_011094464	PREDICTED: uncharacterized protein LOC105174160 isoform X1 [Sesamum indicum].	22.09	430	279	10	61	458	601	1006	7e-07	62.4
rs:WP_005028476	DNA topoisomerase I [Acinetobacter bereziniae].	23.25	443	267	19	42	455	226	624	7e-07	62.4
rs:WP_027003233	DNA topoisomerase I [Flexibacter roseolus].	22.96	318	194	6	40	340	211	494	7e-07	62.4
rs:WP_024160892	MULTISPECIES: topoisomerase I [Acinetobacter].	23.02	443	268	19	42	455	226	624	7e-07	62.4
rs:WP_012781804	DNA topoisomerase I [Flavobacteriaceae bacterium 3519-10].	27.05	281	163	11	77	348	248	495	7e-07	62.4
rs:WP_045924935	DNA topoisomerase I [Bifidobacterium asteroides].	25.58	344	208	12	24	354	242	550	7e-07	62.4
rs:XP_012764839	DNA topoisomerase III, putative [Plasmodium reichenowi].	22.42	397	230	14	37	400	345	696	7e-07	62.0
tr:A0A072TRW2_MEDTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.36	428	260	15	61	450	507	904	7e-07	62.4
rs:WP_040389417	hypothetical protein, partial [Cardiobacterium valvarum].	28.89	135	78	2	221	354	11	128	7e-07	59.3
tr:S4H4H5_GARVA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.66	157	87	2	220	376	125	256	7e-07	62.0
tr:J9D679_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJX08236.1};	35.09	114	69	3	293	402	1	113	7e-07	59.3
tr:W4I7S2_PLAFA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETW39467.1};	22.42	397	230	14	37	400	299	650	7e-07	62.0
rs:XP_001830882	hypothetical protein CC1G_02333 [Coprinopsis cinerea okayama7#130].	27.15	221	122	5	166	377	374	564	7e-07	62.0
tr:A0A068X0K2_ECHGR	SubName: Full=DNA topoisomerase 3 beta 1 {ECO:0000313|EMBL:CDS23493.1};	22.83	438	273	15	40	453	283	679	7e-07	62.0
tr:A0A072TFG8_MEDTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.36	428	260	15	61	450	507	904	7e-07	62.4
rs:WP_024160721	topoisomerase I [Acinetobacter nosocomialis].	23.02	443	268	19	42	455	226	624	7e-07	62.0
tr:W7F6L4_PLAF8	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EUR65568.1};	22.42	397	230	14	37	400	345	696	7e-07	62.0
rs:WP_035147867	hypothetical protein, partial [Lactobacillus sakei].	47.27	55	29	0	67	121	4	58	8e-07	58.2
rs:WP_027378935	DNA topoisomerase I [Chryseobacterium daeguense].	26.49	336	194	12	11	334	182	476	8e-07	62.0
rs:WP_028787284	DNA topoisomerase I [Terrimonas ferruginea].	24.03	308	189	8	36	340	223	488	8e-07	62.0
tr:A0A072TH66_MEDTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.36	428	260	15	61	450	507	904	8e-07	62.0
tr:G9ZIQ3_9GAMM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHM51389.1}; Flags: Fragment;	28.68	136	79	2	220	354	10	128	8e-07	59.3
sp:TOP1_THEMA	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.55	330	194	10	65	377	233	524	8e-07	62.0
rs:WP_035656189	DNA topoisomerase III, partial [Lachnospiraceae bacterium VE202-12].	34.59	133	72	4	317	445	1	122	8e-07	59.3
rs:WP_034006076	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	24.89	225	136	6	225	446	2	196	8e-07	61.6
rs:WP_011278207	DNA topoisomerase I [Sulfolobus acidocaldarius].	24.12	369	223	14	73	424	279	607	8e-07	62.0
rs:WP_037403593	DNA topoisomerase, partial [Solobacterium moorei].	32.33	133	87	1	265	397	1	130	8e-07	58.5
rs:WP_022874262	DNA topoisomerase I [Arthrobacter sp. PAO19].	26.96	293	173	12	77	356	294	558	8e-07	62.0
rs:WP_034072813	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	24.89	225	136	6	225	446	1	195	8e-07	61.6
rs:WP_042827138	DNA topoisomerase I, partial [Xanthomonas axonopodis].	28.38	229	133	9	232	459	2	200	8e-07	60.5
rs:WP_044187322	DNA topoisomerase I [Porphyromonas sp. COT-290 OH860].	25.00	264	152	8	77	334	253	476	8e-07	62.0
tr:E1NRF7_9LACO	SubName: Full=Topoisomerase DNA-binding C4 zinc finger domain protein {ECO:0000313|EMBL:EFO71306.1};	26.26	179	104	6	278	452	8	162	8e-07	58.9
rs:XP_001350185	DNA topoisomerase III, putative [Plasmodium falciparum 3D7].	22.42	397	230	14	37	400	345	696	8e-07	62.0
rs:WP_047471618	DNA topoisomerase I [Acinetobacter pittii].	23.02	443	268	19	42	455	226	624	8e-07	62.0
tr:Q877H4_9CREN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.12	369	223	14	73	424	72	400	8e-07	61.6
rs:WP_008193802	MULTISPECIES: DNA topoisomerase I [Thermotoga].	24.85	330	193	11	65	377	233	524	8e-07	61.6
rs:WP_005962827	DNA topoisomerase III [Fusobacterium necrophorum].	26.90	145	84	3	40	175	228	359	8e-07	61.6
rs:WP_022334923	DNA topoisomerase, partial [Clostridium sp. CAG:452].	21.96	296	196	7	166	454	43	310	8e-07	61.2
rs:WP_024059594	hypothetical protein [Varibaculum cambriense].	25.48	361	202	14	30	362	236	557	8e-07	62.0
rs:XP_007225297	hypothetical protein PRUPE_ppa001274mg [Prunus persica].	22.82	390	240	15	65	434	284	632	8e-07	62.0
rs:WP_035147861	hypothetical protein, partial [Lactobacillus sakei].	37.66	77	48	0	65	141	3	79	8e-07	57.8
rs:WP_041645026	DNA topoisomerase I [Arcobacter butzleri].	25.34	292	173	9	77	350	251	515	8e-07	62.0
rs:WP_013491419	DNA topoisomerase I [Intrasporangium calvum].	28.87	336	188	12	42	356	254	559	8e-07	62.0
rs:WP_039669897	DNA topoisomerase I [Coxiella endosymbiont of Amblyomma americanum].	23.82	403	236	17	77	452	264	622	9e-07	62.0
rs:WP_046996530	DNA topoisomerase I [Arcobacter butzleri].	25.34	292	173	9	77	350	251	515	9e-07	62.0
rs:WP_020848635	DNA topoisomerase I [Arcobacter butzleri].	25.34	292	173	9	77	350	251	515	9e-07	62.0
tr:W6UHW2_ECHGR	SubName: Full=DNA topoisomerase 3-beta-1 {ECO:0000313|EMBL:EUB60643.1};	22.60	438	274	15	40	453	254	650	9e-07	62.0
tr:A8EWX5_ARCB4	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.34	292	173	9	77	350	225	489	9e-07	61.6
rs:WP_026862435	DNA topoisomerase I [Intrasporangiaceae bacterium URHB0013].	27.56	312	173	11	66	356	277	556	9e-07	62.0
rs:WP_024281948	DNA topoisomerase I [Algoriphagus marincola].	25.18	274	169	8	65	334	237	478	9e-07	61.6
rs:WP_046998345	DNA topoisomerase I [Arcobacter butzleri].	25.34	292	173	9	77	350	251	515	9e-07	61.6
rs:WP_040283448	DNA topoisomerase I [Tessaracoccus sp. SIT6].	24.62	325	184	11	51	356	272	554	9e-07	62.0
rs:WP_036857344	hypothetical protein, partial [Prevotella amnii].	33.33	159	83	6	275	425	1	144	9e-07	59.3
rs:WP_026804216	DNA topoisomerase I [Arcobacter sp. AF1581].	25.00	304	182	10	66	350	239	515	9e-07	61.6
tr:X6P1T3_RETFI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	21.94	319	181	9	37	337	117	385	9e-07	61.2
rs:WP_014469493	DNA topoisomerase I [Arcobacter butzleri].	25.34	292	173	9	77	350	251	515	9e-07	61.6
rs:WP_026808340	MULTISPECIES: DNA topoisomerase I [Arcobacter].	25.00	304	182	10	66	350	239	515	9e-07	61.6
rs:XP_006957843	prokaryotic type I DNA topoisomerase [Wallemia sebi CBS 633.66].	25.79	221	125	6	166	377	350	540	9e-07	61.6
rs:WP_034354030	TopA [Helicobacter sp. MIT 09-6949].	24.91	293	181	9	72	354	250	513	1e-06	61.6
rs:WP_047022332	DNA topoisomerase I [Arcobacter butzleri].	25.34	292	173	9	77	350	251	515	1e-06	61.6
rs:WP_034718510	DNA topoisomerase I [Chryseobacterium antarcticum].	24.62	325	189	12	36	349	217	496	1e-06	61.6
rs:XP_008659454	PREDICTED: uncharacterized protein LOC103638270 isoform X2 [Zea mays].	22.55	439	269	16	47	450	545	947	1e-06	62.0
rs:WP_046995026	DNA topoisomerase I [Arcobacter butzleri].	25.34	292	173	9	77	350	251	515	1e-06	61.6
rs:WP_046992000	DNA topoisomerase I [Arcobacter butzleri].	25.34	292	173	9	77	350	251	515	1e-06	61.6
rs:WP_034227298	DNA topoisomerase I [Actinotalea ferrariae].	25.72	381	221	12	42	387	257	610	1e-06	61.6
tr:A0A0B7NMT1_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.41	346	221	9	59	393	281	593	1e-06	61.6
rs:WP_022014138	DNA topoisomerase [Clostridium sp. CAG:122].	34.75	118	71	4	289	401	1	117	1e-06	58.5
rs:WP_046993897	DNA topoisomerase I [Arcobacter butzleri].	25.34	292	173	9	77	350	251	515	1e-06	61.6
rs:WP_023251208	DNA topoisomerase III, partial [Salmonella enterica].	41.10	73	43	0	313	385	2	74	1e-06	58.2
rs:XP_002869340	DNA topoisomerase family protein [Arabidopsis lyrata subsp. lyrata].	22.94	462	265	15	26	450	751	1158	1e-06	62.0
rs:WP_030195387	DNA topoisomerase I [Corynebacterium variabile].	27.07	314	172	12	66	356	277	556	1e-06	61.6
rs:WP_025020460	DNA topoisomerase I [Lactobacillus equi].	23.50	417	255	17	55	452	227	598	1e-06	61.6
rs:WP_005883933	DNA topoisomerase I [Brevibacterium mcbrellneri].	25.39	319	189	11	56	356	273	560	1e-06	61.6
tr:V7HYT0_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.50	417	255	17	55	452	207	578	1e-06	61.6
rs:WP_029038870	DNA topoisomerase I [Salinimicrobium xinjiangense].	25.17	302	183	9	36	334	218	479	1e-06	61.6
tr:X1DEL1_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_S07187 {ECO:0000313|EMBL:GAG94866.1}; Flags: Fragment;	30.10	196	104	9	270	456	5	176	1e-06	60.1
rs:WP_014889101	topoisomerase I [secondary endosymbiont of Heteropsylla cubana].	23.08	390	229	18	77	446	281	619	1e-06	61.6
tr:K1TPQ8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC75062.1}; Flags: Fragment;	33.07	127	75	3	311	431	14	136	1e-06	58.5
rs:WP_026641743	DNA topoisomerase I [Bifidobacterium tsurumiense].	25.22	337	199	10	42	354	258	565	1e-06	61.6
tr:W7JI63_PLAFA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EWC74513.1};	22.69	335	196	11	37	353	299	588	1e-06	61.2
tr:T2PIP7_GARVA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.03	157	88	2	220	376	125	256	1e-06	61.2
rs:WP_020490544	hypothetical protein [Dehalobacter sp. FTH1].	25.00	336	184	12	77	380	291	590	1e-06	61.6
rs:WP_003787886	DNA topoisomerase I [Actinomyces viscosus].	26.81	373	195	17	44	377	268	601	1e-06	61.6
rs:XP_004498561	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Cicer arietinum].	22.09	430	279	13	61	458	490	895	1e-06	61.6
rs:WP_013061650	DNA topoisomerase I [Salinibacter ruber].	25.62	320	194	10	41	344	254	545	1e-06	61.6
rs:WP_022869417	DNA topoisomerase I [Yaniella halotolerans].	24.79	355	213	11	42	376	261	581	1e-06	61.6
rs:WP_036848572	DNA topoisomerase I, partial [Porphyromonas sp. COT-108 OH1349].	26.86	175	119	3	211	377	1	174	1e-06	60.1
rs:XP_003051867	predicted protein [Nectria haematococca mpVI 77-13-4].	23.59	284	173	8	59	335	274	520	1e-06	61.2
tr:K2BY26_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EKD67089.1};	24.36	234	140	6	152	377	33	237	1e-06	60.8
rs:XP_008222782	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Prunus mume].	22.82	390	240	15	65	434	284	632	1e-06	61.6
rs:WP_032056289	DNA topoisomerase I [Acinetobacter baumannii].	23.02	443	268	19	42	455	226	624	1e-06	61.6
rs:WP_006290777	DNA topoisomerase I [Parascardovia denticolens].	23.82	361	219	11	42	376	270	600	1e-06	61.6
rs:WP_026976557	DNA topoisomerase I [Flavobacterium tegetincola].	26.24	263	154	8	77	334	249	476	1e-06	61.2
rs:WP_013048901	DNA topoisomerase I [Aminobacterium colombiense].	22.10	439	265	17	47	457	238	627	1e-06	61.2
tr:F3CGX8_PSESG	SubName: Full=Orf50 {ECO:0000313|EMBL:EGH18520.1}; Flags: Fragment;	37.10	62	39	0	106	167	1	62	1e-06	56.6
rs:WP_022859916	DNA topoisomerase I [Bifidobacterium magnum].	24.85	326	196	10	42	354	258	547	1e-06	61.6
tr:A0A024W0X4_PLAFA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETW34589.1};	22.76	369	209	13	63	400	314	637	1e-06	61.2
rs:XP_008222783	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Prunus mume].	22.82	390	240	15	65	434	157	505	1e-06	61.2
rs:WP_009032645	DNA topoisomerase I [Indibacter alkaliphilus].	26.82	261	159	8	77	334	248	479	1e-06	61.2
rs:WP_007108079	DNA topoisomerase I [Natrinema altunense].	25.00	224	152	5	74	296	281	489	1e-06	61.6
rs:WP_034246926	DNA topoisomerase I [Aquimarina atlantica].	25.64	273	160	10	68	334	241	476	1e-06	61.2
rs:WP_020166935	MULTISPECIES: DNA topoisomerase I [Methylotenera].	23.96	409	254	13	60	449	246	616	1e-06	61.2
rs:WP_006291385	DNA topoisomerase I [Parascardovia denticolens].	23.82	361	219	11	42	376	270	600	1e-06	61.2
rs:WP_028376425	DNA topoisomerase I [Leeuwenhoekiella sp. Hel_I_48].	24.44	266	155	8	77	334	249	476	1e-06	61.2
rs:WP_004511123	DNA topoisomerase I [Arcobacter butzleri].	25.34	292	173	9	77	350	251	515	1e-06	61.2
rs:WP_028289569	DNA topoisomerase I [Olleya sp. VCSA23].	25.67	261	158	9	77	334	249	476	1e-06	61.2
rs:WP_002669720	DNA topoisomerase, partial [Capnocytophaga gingivalis].	25.93	270	163	8	68	334	3	238	1e-06	61.2
rs:WP_045501272	DNA topoisomerase I [Chryseobacterium sp. StRB126].	26.40	322	184	12	24	334	197	476	1e-06	61.2
rs:WP_023252398	DNA topoisomerase III, partial [Salmonella enterica].	37.31	67	42	0	36	102	9	75	1e-06	56.6
rs:WP_028607340	DNA topoisomerase I [Olleya sp. VCSM12].	25.67	261	158	9	77	334	249	476	1e-06	61.2
rs:WP_035835015	hypothetical protein, partial [Cupriavidus metallidurans].	25.51	294	176	10	74	354	100	363	1e-06	60.5
rs:WP_004137143	DNA topoisomerase I [Gardnerella vaginalis].	29.85	134	73	2	221	354	440	552	1e-06	61.2
rs:XP_006844098	PREDICTED: uncharacterized protein LOC18433959 [Amborella trichopoda].	23.35	454	267	18	41	449	600	1017	1e-06	61.2
rs:WP_048323346	DNA topoisomerase I, partial [Crocosphaera watsonii].	26.82	179	98	5	166	339	44	194	1e-06	58.5
rs:WP_024285812	DNA topoisomerase I [Cellulomonas sp. KRMCY2].	25.47	369	189	14	42	356	257	593	1e-06	61.2
rs:WP_002351481	hypothetical protein, partial [Enterococcus faecium].	27.61	134	88	3	156	286	25	152	1e-06	57.8
tr:S9U416_9TRYP	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EPY23658.1};	22.97	418	241	17	30	392	272	663	1e-06	61.2
rs:WP_010717408	hypothetical protein, partial [Enterococcus faecalis].	28.97	145	87	4	320	455	1	138	1e-06	57.8
rs:WP_025146647	DNA topoisomerase I [Sphingobacterium sp. H1ai].	24.84	310	190	8	29	335	212	481	1e-06	61.2
rs:WP_020365095	DNA topoisomerase III, partial [Pseudomonas syringae].	42.03	69	40	0	293	361	1	69	1e-06	56.6
rs:WP_032517299	hypothetical protein [Peptoclostridium difficile].	34.04	141	77	5	311	445	14	144	2e-06	58.5
rs:WP_005006203	DNA topoisomerase I [Acinetobacter ursingii].	23.02	443	268	19	42	455	226	624	2e-06	61.2
rs:WP_034930967	DNA topoisomerase I, partial [Candidatus Accumulibacter sp. SK-01].	30.39	181	93	6	278	454	12	163	2e-06	60.1
rs:WP_035148387	DNA topoisomerase I [Campylobacter fetus].	22.87	363	227	14	41	385	217	544	2e-06	60.8
tr:W1PCV0_AMBTC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.35	454	267	18	41	449	593	1010	2e-06	61.2
tr:V5I9Z2_ANOGL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.85	157	93	7	85	237	4	150	2e-06	58.2
tr:S9V0P8_9TRYP	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EPY20486.1};	23.53	374	207	16	74	392	314	663	2e-06	60.8
tr:F2THD6_AJEDA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.64	276	159	8	73	339	301	536	2e-06	60.8
rs:WP_033017353	DNA topoisomerase III, partial [Geobacillus stearothermophilus].	27.07	181	114	6	74	245	210	381	2e-06	60.5
rs:WP_013992519	DNA topoisomerase I [Zobellia galactanivorans].	25.77	260	161	7	77	334	249	478	2e-06	60.8
rs:WP_022263701	ATPase AAA [Clostridium sp. CAG:352].	36.27	102	63	2	294	393	83	184	2e-06	58.2
rs:XP_002489893	DNA Topoisomerase III, conserved protein that functions in a complex with Sgs1p and Rmi1p [Komagataella pastoris GS115].	23.82	361	220	12	73	417	298	619	2e-06	60.8
rs:XP_006382211	hypothetical protein POPTR_0006s29400g [Populus trichocarpa].	22.17	433	275	14	61	458	563	968	2e-06	61.2
rs:WP_043041427	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	23.02	443	268	19	42	455	226	624	2e-06	60.8
tr:X1DFG5_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_S06633 {ECO:0000313|EMBL:GAH03804.1}; Flags: Fragment;	28.14	167	88	5	214	377	71	208	2e-06	59.3
tr:F9WKC3_TRYVY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.26	344	225	9	44	379	145	457	2e-06	60.8
rs:WP_039426347	DNA topoisomerase I, partial [Porphyromonas gulae].	31.07	103	60	2	74	176	107	198	2e-06	58.2
rs:WP_045190613	DNA topoisomerase I [Terrabacter sp. 28].	25.74	373	217	13	31	377	242	580	2e-06	60.8
rs:WP_042473284	hypothetical protein [Bacillus sp. FF3].	30.33	122	80	2	181	302	9	125	2e-06	57.4
rs:XP_004184100	DNA topoisomerase 3-beta-1, putative [Entamoeba invadens IP1].	21.79	390	258	12	21	393	230	589	2e-06	60.8
rs:XP_009798204	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Nicotiana sylvestris].	27.23	235	145	10	18	237	250	473	2e-06	60.5
rs:XP_011006669	PREDICTED: uncharacterized protein LOC105112620 [Populus euphratica].	22.17	433	275	14	61	458	567	972	2e-06	60.8
rs:XP_004291220	PREDICTED: uncharacterized protein LOC101314719 isoform X1 [Fragaria vesca subsp. vesca].	23.46	439	262	17	61	458	676	1081	2e-06	61.2
rs:WP_017731204	hypothetical protein [Nafulsella turpanensis].	25.26	285	173	10	68	346	241	491	2e-06	60.8
rs:WP_027310435	DNA topoisomerase I [Bacteroidetes bacterium SCGC AAA027-N21].	26.24	263	154	9	77	334	249	476	2e-06	60.8
rs:WP_013557841	DNA topoisomerase I [Deinococcus maricopensis].	24.84	306	185	11	54	344	264	539	2e-06	60.8
rs:WP_041667983	hypothetical protein [Ralstonia pickettii].	36.63	101	55	5	354	454	1	92	2e-06	57.4
rs:WP_044103448	DNA topoisomerase I [Acinetobacter pittii].	23.25	443	267	19	42	455	226	624	2e-06	60.8
tr:M5S1H6_9PLAN	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EMI21512.1};	24.74	194	122	3	166	354	46	220	2e-06	60.5
rs:XP_006483648	PREDICTED: uncharacterized protein LOC102624144 isoform X3 [Citrus sinensis].	24.19	434	246	17	71	458	609	1005	2e-06	60.8
rs:WP_040694667	DNA topoisomerase I [Propionimicrobium lymphophilum].	24.29	350	201	13	47	370	259	570	2e-06	60.8
rs:WP_031826169	DNA topoisomerase III, partial [Staphylococcus aureus].	26.21	145	96	2	35	173	227	366	2e-06	60.1
rs:WP_025663347	DNA topoisomerase I [Aquimarina megaterium].	25.64	273	160	10	68	334	241	476	2e-06	60.8
rs:WP_031811100	DNA topoisomerase III, partial [Staphylococcus aureus].	26.21	145	96	2	35	173	227	366	2e-06	60.1
tr:K2AAG8_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	22.00	400	258	12	65	454	163	518	2e-06	60.5
tr:T0L554_9NEIS	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	29.86	144	75	5	74	194	263	403	2e-06	60.1
tr:H6RXG4_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.57	297	179	9	48	334	218	476	2e-06	60.8
tr:C7H1D5_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEU98145.1};	32.61	138	80	3	311	445	14	141	2e-06	58.2
rs:WP_014773067	DNA topoisomerase I [Belliella baltica].	23.79	290	181	7	47	334	228	479	2e-06	60.5
rs:XP_010048495	PREDICTED: uncharacterized protein LOC104437275 [Eucalyptus grandis].	21.80	445	276	14	54	458	586	998	2e-06	60.8
tr:X0ZMD5_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_L02471 {ECO:0000313|EMBL:GAG70519.1}; Flags: Fragment;	26.63	199	116	5	166	354	12	190	2e-06	58.5
rs:WP_008200254	DNA topoisomerase I [Algoriphagus machipongonensis].	24.23	260	167	5	77	334	248	479	2e-06	60.5
tr:J6YG10_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJX60929.1}; Flags: Fragment;	34.69	98	58	2	207	304	2	93	2e-06	56.6
rs:XP_006483646	PREDICTED: uncharacterized protein LOC102624144 isoform X1 [Citrus sinensis].	24.19	434	246	17	71	458	611	1007	2e-06	60.8
tr:K1ZHR3_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	20.69	435	278	12	41	454	223	611	2e-06	60.5
rs:XP_006483647	PREDICTED: uncharacterized protein LOC102624144 isoform X2 [Citrus sinensis].	24.19	434	246	17	71	458	610	1006	2e-06	60.8
rs:XP_007407518	hypothetical protein MELLADRAFT_34533, partial [Melampsora larici-populina 98AG31].	23.64	423	254	17	18	414	230	609	2e-06	60.5
rs:WP_028283498	DNA topoisomerase I [Olleya marilimosa].	25.29	261	159	9	77	334	249	476	2e-06	60.5
rs:WP_033647056	hypothetical protein [Enterococcus faecium].	35.29	102	64	1	293	392	1	102	2e-06	57.0
tr:A0A0C7CJ92_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.82	319	187	9	73	377	59	335	2e-06	60.5
tr:X1NPT8_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S01156 {ECO:0000313|EMBL:GAI32226.1}; Flags: Fragment;	23.84	302	171	8	77	354	19	285	2e-06	59.3
rs:WP_002349797	DNA topoisomerase, partial [Enterococcus faecium].	32.14	140	89	3	57	193	268	404	2e-06	60.1
rs:WP_036532336	DNA topoisomerase I, partial [Nocardia cyriacigeorgica].	27.94	136	80	2	221	356	2	119	2e-06	60.1
rs:WP_038268974	DNA topoisomerase I [Zhouia amylolytica].	26.22	267	150	11	77	334	249	477	2e-06	60.5
tr:S2VZR6_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.29	350	201	13	47	370	267	578	2e-06	60.5
tr:A0A009GG41_ACIBA	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EXA89529.1};	26.02	246	144	10	206	446	5	217	2e-06	60.1
rs:WP_016636986	DNA topoisomerase I, partial [Gardnerella vaginalis].	30.13	156	84	3	221	376	409	539	2e-06	60.5
tr:A0A067MUU8_9HOMO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.06	360	217	12	39	377	259	579	2e-06	60.5
rs:WP_032583509	DNA topoisomerase I, partial [Bacteroides fragilis].	31.06	161	95	5	275	430	11	160	2e-06	58.2
rs:WP_032814236	DNA topoisomerase I [Gardnerella vaginalis].	30.13	156	84	3	221	376	440	570	2e-06	60.5
rs:WP_038025549	DNA topoisomerase I [Tenacibaculum maritimum].	24.83	302	187	10	45	340	218	485	2e-06	60.5
rs:WP_015691241	DNA topoisomerase I [Saprospira grandis].	25.98	254	166	7	47	294	234	471	3e-06	60.5
tr:A0A096RLJ4_MAIZE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.47	277	170	9	65	337	127	365	3e-06	59.7
tr:S5ZEH2_9CREN	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AGT35503.1};	25.69	288	162	10	95	370	305	552	3e-06	60.1
tr:X1EGZ0_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_L04006 {ECO:0000313|EMBL:GAH32571.1}; Flags: Fragment;	24.76	319	184	10	6	295	46	337	3e-06	59.3
rs:WP_024720786	DNA topoisomerase III [Clostridiales bacterium VE202-01].	34.17	120	70	4	79	193	264	379	3e-06	60.1
rs:WP_004118458	DNA topoisomerase I [Gardnerella vaginalis].	31.11	135	68	3	221	354	440	550	3e-06	60.5
rs:WP_045716084	DNA topoisomerase I, partial [Salmonella enterica].	28.08	203	118	6	247	446	2	179	3e-06	59.7
rs:XP_010926664	PREDICTED: DNA topoisomerase 3-beta isoform X1 [Elaeis guineensis].	24.07	295	175	11	65	351	284	537	3e-06	60.5
tr:A0A0F3GLV0_9BACT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJU81678.1};	23.28	232	148	7	227	454	1	206	3e-06	59.3
tr:A0A0C7BQ63_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.82	319	187	9	73	377	298	574	3e-06	60.1
tr:I1QMB1_ORYGL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.60	203	142	5	39	237	451	650	3e-06	60.5
tr:A0A093ZR94_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY13575.1};	24.41	340	206	12	10	339	252	550	3e-06	60.1
rs:WP_044548130	DNA topoisomerase I, partial [Parabacteroides distasonis].	27.95	161	107	4	225	377	4	163	3e-06	57.4
rs:WP_033191919	DNA topoisomerase I [Fervidobacterium islandicum].	24.38	324	196	9	70	377	274	564	3e-06	60.1
rs:XP_003378587	DNA topoisomerase 3-beta-1 protein [Trichinella spiralis].	21.35	370	247	11	40	394	209	549	3e-06	60.1
rs:WP_004104755	DNA topoisomerase I [Gardnerella vaginalis].	31.11	135	68	3	221	354	440	550	3e-06	60.1
rs:WP_028821435	DNA topoisomerase I [Propionimicrobium lymphophilum].	23.93	351	201	13	47	370	259	570	3e-06	60.1
rs:WP_040163391	DNA topoisomerase I [bacterium SIT7].	23.48	328	194	11	86	384	301	600	3e-06	60.1
rs:WP_024111510	DNA topoisomerase I [Propionimicrobium sp. BV2F7].	24.29	350	201	13	47	370	259	570	3e-06	60.1
rs:WP_016989276	DNA topoisomerase I [Flavobacterium sp. ACAM 123].	26.24	263	154	8	77	334	249	476	3e-06	60.1
rs:WP_047441458	DNA topoisomerase I [Chryseobacterium sp. YR561].	25.46	326	191	13	36	352	217	499	3e-06	60.1
rs:XP_008659453	PREDICTED: uncharacterized protein LOC103638270 isoform X1 [Zea mays].	22.32	439	272	15	47	450	545	949	3e-06	60.5
rs:XP_008659455	PREDICTED: uncharacterized protein LOC103638270 isoform X3 [Zea mays].	22.32	439	272	15	47	450	545	949	3e-06	60.1
rs:WP_004129275	DNA topoisomerase I [Gardnerella vaginalis].	30.60	134	70	3	221	354	440	550	3e-06	60.1
rs:XP_001026048	DNA topoisomerase I [Tetrahymena thermophila SB210].	22.54	315	200	10	71	377	827	1105	3e-06	60.5
tr:A0A0A1PE23_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.82	319	187	9	73	377	298	574	3e-06	60.1
rs:XP_004223545	DNA topoisomerase III alpha [Plasmodium cynomolgi strain B].	23.42	333	210	10	64	385	310	608	3e-06	60.1
tr:A0A0C7BMU4_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.82	319	187	9	73	377	246	522	3e-06	60.1
rs:WP_034558163	DNA topoisomerase I [Helicobacter muridarum].	20.73	439	276	16	41	455	248	638	3e-06	60.1
rs:WP_033514412	DNA topoisomerase I [Bifidobacterium pullorum].	24.20	343	209	10	34	354	250	563	3e-06	60.1
rs:WP_008510351	DNA topoisomerase I [Mucilaginibacter paludis].	24.01	304	187	8	36	335	217	480	3e-06	60.1
tr:S5W9P8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.14	140	89	3	57	193	223	359	3e-06	59.3
rs:XP_008815780	DNA topoisomerase III [Plasmodium inui San Antonio 1].	24.32	333	207	11	64	385	319	617	3e-06	59.7
tr:A0A094HSQ5_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFZ11286.1};	23.58	335	212	10	12	339	231	528	3e-06	59.7
rs:WP_022470160	DNA topoisomerase III, partial [Bacteroides thetaiotaomicron CAG:40].	30.16	126	86	2	260	384	1	125	3e-06	56.6
tr:H8H3H1_DEIGI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.42	316	197	6	42	350	246	523	3e-06	59.7
rs:WP_006001245	MULTISPECIES: topoisomerase [Clostridiales].	36.46	96	61	0	301	396	6	101	4e-06	56.2
rs:WP_047792006	hypothetical protein, partial [Spiroplasma eriocheiris].	25.50	302	181	10	86	377	260	527	4e-06	59.7
rs:WP_011153312	hypothetical protein [Nanoarchaeum equitans].	37.14	105	42	4	277	377	34	118	4e-06	57.0
rs:WP_022826790	DNA topoisomerase I [Flavobacterium antarcticum].	25.86	263	155	8	77	334	249	476	4e-06	60.1
rs:WP_039351117	DNA topoisomerase I [Chryseobacterium jeonii].	26.95	282	168	10	77	351	248	498	4e-06	60.1
rs:WP_007270845	DNA topoisomerase I [Arthrobacter gangotriensis].	25.00	336	196	12	42	356	260	560	4e-06	60.1
rs:WP_012789627	DNA topoisomerase I [Chitinophaga pinensis].	24.25	268	172	7	77	342	255	493	4e-06	59.7
rs:XP_002528003	prokaryotic DNA topoisomerase, putative [Ricinus communis].	23.96	313	187	10	61	350	534	818	4e-06	60.1
rs:WP_015453828	hypothetical protein [Helicobacter cinaedi].	24.40	291	172	12	77	350	256	515	4e-06	59.7
rs:WP_028843537	DNA topoisomerase I [Pseudothermotoga elfii].	24.61	317	188	12	74	377	245	523	4e-06	59.7
rs:WP_047290391	DNA topoisomerase I [Bifidobacterium bifidum].	25.95	343	195	13	42	354	258	571	4e-06	59.7
rs:WP_002659914	DNA topoisomerase I [Saprospira grandis].	25.98	254	166	7	47	294	234	471	4e-06	59.7
gp:CP011856_497	reverse gyrase [Spiroplasma eriocheiris CCTCC M 207170]	25.50	302	181	10	86	377	260	527	4e-06	59.3
rs:WP_012002246	DNA topoisomerase I [Pseudothermotoga lettingae].	24.44	315	191	10	74	377	245	523	4e-06	59.7
tr:M6HCU2_LEPIR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.53	324	201	9	40	350	82	368	4e-06	59.3
rs:WP_037360135	DNA topoisomerase I [Schleiferia thermophila].	25.95	262	157	7	77	334	249	477	4e-06	59.7
tr:F3GR44_PSESJ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGH49547.1}; Flags: Fragment;	57.14	42	18	0	77	118	1	42	4e-06	54.7
rs:WP_026408454	DNA topoisomerase I [Actinomyces gerencseriae].	25.91	386	208	16	45	388	286	635	4e-06	59.7
rs:WP_033237235	topoisomerase I [Rhodococcus rhodochrous].	25.42	354	203	15	69	403	277	588	4e-06	59.7
rs:XP_004965229	PREDICTED: uncharacterized protein LOC101772280 isoform X1 [Setaria italica].	21.51	423	274	12	61	450	560	957	4e-06	59.7
rs:WP_030526578	DNA topoisomerase I [Phycicoccus jejuensis].	24.92	333	199	11	42	356	252	551	4e-06	59.7
rs:WP_043805158	hypothetical protein, partial [Deinococcus gobiensis].	23.42	316	197	6	42	350	246	523	4e-06	59.3
rs:WP_002350895	DNA topoisomerase, partial [Enterococcus faecium].	32.61	138	87	3	57	191	217	351	5e-06	58.9
rs:WP_003783813	DNA topoisomerase I [Actinomyces naeslundii].	27.47	375	190	17	44	377	268	601	5e-06	59.7
rs:WP_046288885	DNA topoisomerase I [Blochmannia endosymbiont of Polyrhachis (Hedomyrma) turneri].	21.05	285	187	6	77	356	284	535	5e-06	59.7
rs:XP_004965230	PREDICTED: uncharacterized protein LOC101772280 isoform X2 [Setaria italica].	21.51	423	274	12	61	450	560	957	5e-06	59.7
rs:WP_034631506	DNA topoisomerase I [Cellulomonas cellasea].	23.49	413	218	12	40	387	258	637	5e-06	59.7
rs:XP_009772612	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Nicotiana sylvestris].	21.91	429	265	14	61	450	613	1010	5e-06	59.7
tr:C0B640_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEG91174.1};	35.23	88	57	0	311	398	14	101	5e-06	57.0
rs:WP_022173864	DNA topoisomerase [Bifidobacterium bifidum CAG:234].	25.48	365	213	13	42	376	258	593	5e-06	59.7
tr:K1XW10_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.56	266	157	8	77	335	248	479	5e-06	59.3
rs:WP_046742933	DNA topoisomerase I [Kordia sp. MCCC 1A00726].	27.30	315	178	12	35	334	198	476	5e-06	59.3
rs:WP_000054705	DNA topoisomerase I, partial [Leptospira interrogans].	22.53	324	201	9	40	350	211	497	5e-06	59.3
rs:XP_012177953	predicted protein [Fibroporia radiculosa].	23.53	357	220	11	39	380	256	574	5e-06	59.7
rs:WP_042721985	DNA topoisomerase I [Flavobacterium sp. B17].	26.09	322	185	12	24	334	191	470	5e-06	59.3
rs:WP_013390327	DNA topoisomerase I [Bifidobacterium bifidum].	25.95	343	195	13	42	354	258	571	5e-06	59.3
rs:WP_039369837	DNA topoisomerase I [Chryseobacterium taiwanense].	25.32	308	182	11	51	351	232	498	5e-06	59.3
rs:XP_009772613	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Nicotiana sylvestris].	21.91	429	265	14	61	450	611	1008	5e-06	59.3
rs:WP_047284835	DNA topoisomerase I [Bifidobacterium bifidum].	25.48	365	213	13	42	376	258	593	6e-06	59.3
tr:K1UJ58_9ZZZZ	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EKC80054.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EKC80054.1}; Flags: Fragment;	30.40	125	79	4	47	165	47	169	6e-06	56.2
tr:X6P674_RETFI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.12	312	193	8	37	331	267	545	6e-06	58.9
rs:WP_047298465	DNA topoisomerase I [Bifidobacterium bifidum].	25.48	365	213	13	42	376	258	593	6e-06	59.3
tr:G0LYM1_LACPE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	38.14	97	55	3	29	121	34	129	6e-06	55.8
rs:WP_044647931	DNA topoisomerase III, partial [Paenibacillus terrae].	33.67	98	63	2	50	147	260	355	6e-06	58.5
gp:CP007493_220	DNA topoisomerase I [Thermofilum carboxyditrophus 1505]	25.87	286	164	11	95	370	305	552	6e-06	58.9
tr:A0A072VE62_MEDTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.07	426	268	13	61	450	507	904	6e-06	59.3
tr:F9MPK8_9FIRM	SubName: Full=Topoisomerase DNA-binding C4 zinc finger domain protein {ECO:0000313|EMBL:EGS33105.1};	29.37	126	69	5	331	452	4	113	6e-06	55.8
tr:A0A072VD72_MEDTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.07	426	268	13	61	450	507	904	6e-06	59.3
rs:WP_013363982	DNA topoisomerase I [Bifidobacterium bifidum].	25.95	343	195	13	42	354	258	571	6e-06	59.3
tr:X1H5W4_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S01381 {ECO:0000313|EMBL:GAH49254.1}; Flags: Fragment;	24.41	299	175	10	65	358	43	295	6e-06	58.2
rs:WP_032602306	DNA topoisomerase I, partial [Bacteroides fragilis].	29.85	134	92	2	277	409	1	133	6e-06	55.8
rs:WP_045750540	DNA topoisomerase I [Methylophilaceae bacterium MMS-10A-171].	23.98	417	244	18	60	449	246	616	6e-06	59.3
rs:WP_034701543	DNA topoisomerase I [Chryseobacterium luteum].	26.25	301	179	10	36	334	217	476	6e-06	59.3
tr:X1M0K1_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S07022 {ECO:0000313|EMBL:GAI24893.1}; Flags: Fragment;	24.91	285	173	9	179	452	4	258	6e-06	57.8
rs:WP_009255105	hypothetical protein [Lachnospiraceae bacterium 3_1_57FAA_CT1].	32.12	165	85	7	290	445	1	147	7e-06	57.0
tr:C2FZU8_9SPHI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEI91544.1};	25.46	216	152	5	218	427	5	217	7e-06	57.8
rs:WP_007148249	DNA topoisomerase I [Scardovia wiggsiae].	23.44	384	202	12	41	377	269	607	7e-06	59.3
rs:WP_018474198	DNA topoisomerase I [Echinicola pacifica].	23.75	261	167	6	77	334	248	479	7e-06	58.9
rs:WP_003814159	DNA topoisomerase I [Bifidobacterium bifidum].	25.95	343	195	13	42	354	258	571	7e-06	58.9
rs:WP_033659060	hypothetical protein, partial [Enterococcus faecium].	47.62	63	32	1	260	322	1	62	7e-06	54.3
rs:WP_048465246	DNA topoisomerase, partial [Methylobacterium aquaticum].	31.22	205	129	7	47	243	243	443	7e-06	58.5
tr:K6W5C8_9MICO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.24	301	177	10	77	363	309	581	7e-06	58.9
rs:WP_034247793	DNA topoisomerase I [Actinotalea fermentans].	24.79	359	208	13	30	356	243	571	8e-06	58.9
tr:I1BRB7_RHIO9	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.31	326	199	8	53	369	185	468	8e-06	58.5
rs:WP_046934581	hypothetical protein, partial [Xanthomonas perforans].	26.46	189	108	5	275	459	6	167	8e-06	57.4
tr:X0SJG8_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_L03787 {ECO:0000313|EMBL:GAF76007.1}; Flags: Fragment;	25.10	239	134	9	77	294	216	430	8e-06	58.2
rs:WP_026712288	DNA topoisomerase I [Flavobacterium daejeonense].	25.48	263	156	9	77	334	249	476	8e-06	58.9
rs:WP_009746823	DNA topoisomerase I [Actinomyces sp. oral taxon 170].	26.42	386	206	16	44	388	268	616	8e-06	58.9
rs:WP_047184914	DNA topoisomerase III, partial [Bacilli bacterium VT-13-104].	26.12	134	92	2	40	169	237	367	8e-06	58.2
rs:WP_040321351	DNA topoisomerase I [Austwickia chelonae].	27.15	302	178	10	77	364	287	560	9e-06	58.9
tr:X3XGZ6_SALEN	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AHS53776.1}; Flags: Fragment;	27.46	193	117	5	257	446	1	173	9e-06	57.8
rs:WP_043562350	DNA topoisomerase I [Actinomyces israelii].	25.71	350	184	14	45	356	285	596	1e-05	58.5
rs:WP_047429017	DNA topoisomerase I [Chryseobacterium sp. YR477].	26.92	286	166	10	51	334	232	476	1e-05	58.5