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TARA_ERS490285_N000666_19 / Result of BLASTP

browse BLASTP result of all genes from this scaffold

subject	subject definition	idt	len	mis	gap	q.start	q.end	s.start	s.end	evalue	bit.score
subject	subject definition	idt	len	mis	gap	q.start	q.end	s.start	s.end	evalue	bit.score
rs:WP_005853443	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Sulfitobacter].	98.47	131	2	0	1	131	1	131	6e-90	269
rs:WP_009824567	phosphoribosyl-AMP cyclohydrolase [Sulfitobacter sp. NAS-14.1].	97.71	131	3	0	1	131	1	131	2e-89	268
rs:WP_037966371	phosphoribosyl-AMP cyclohydrolase [Sulfitobacter pontiacus].	96.95	131	4	0	1	131	1	131	1e-88	265
tr:A0A085BUR9_9RHOB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	99.17	121	1	0	11	131	1	121	8e-83	250
rs:WP_008225117	phosphoribosyl-AMP cyclohydrolase [Roseobacter sp. GAI101].	85.47	117	17	0	11	127	1	117	8e-70	217
rs:WP_045996199	phosphoribosyl-AMP cyclohydrolase [Loktanella sp. S4079].	79.17	120	25	0	11	130	1	120	4e-67	210
rs:WP_008756573	phosphoribosyl-AMP cyclohydrolase [Rhodobacteraceae bacterium KLH11].	76.86	121	27	1	2	121	1	121	5e-63	200
rs:WP_037306913	phosphoribosyl-AMP cyclohydrolase [Ruegeria halocynthiae].	80.73	109	21	0	13	121	13	121	2e-61	196
rs:WP_019953652	phosphoribosyl-AMP cyclohydrolase [Loktanella vestfoldensis].	78.38	111	24	0	11	121	1	111	2e-61	196
sp:HIS3_RUEPO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	79.28	111	23	0	11	121	1	111	2e-61	196
rs:WP_039133042	phosphoribosyl-AMP cyclohydrolase [Leisingera sp. ANG-Vp].	78.76	113	24	0	9	121	3	115	8e-61	194
rs:WP_037244329	phosphoribosyl-AMP cyclohydrolase [Roseovarius sp. MCTG156(2b)].	73.55	121	32	0	11	131	1	121	1e-60	194
rs:WP_039161298	phosphoribosyl-AMP cyclohydrolase [Leisingera sp. ANG-M1].	80.18	111	22	0	11	121	1	111	1e-60	194
rs:WP_008236181	phosphoribosyl-AMP cyclohydrolase [Roseobacter sp. CCS2].	75.42	118	29	0	11	128	1	118	3e-60	193
rs:WP_039535464	phosphoribosyl-AMP cyclohydrolase [Ruegeria sp. ANG-R].	77.68	112	25	0	10	121	10	121	4e-60	192
rs:WP_005982996	phosphoribosyl-AMP cyclohydrolase [Ruegeria lacuscaerulensis].	79.46	112	23	0	10	121	10	121	4e-60	192
rs:WP_009815031	phosphoribosyl-AMP cyclohydrolase [Roseovarius nubinhibens].	76.58	111	26	0	11	121	1	111	1e-59	191
rs:WP_024097381	phosphoribosyl-AMP cyclohydrolase [Phaeobacter gallaeciensis].	76.79	112	26	0	10	121	6	117	1e-59	191
rs:WP_010440005	phosphoribosyl-AMP cyclohydrolase [Ruegeria conchae].	77.06	109	25	0	13	121	13	121	2e-59	191
rs:WP_008204557	phosphoribosyl-AMP cyclohydrolase [Roseobacter sp. SK209-2-6].	76.79	112	26	0	10	121	6	117	2e-59	191
sp:HIS3_RHOSK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	72.03	118	33	0	11	128	1	118	3e-59	190
rs:WP_002719775	phosphoribosyl-AMP cyclohydrolase [Rhodobacter sphaeroides].	72.03	118	33	0	11	128	1	118	3e-59	190
rs:WP_039687773	phosphoribosyl-AMP cyclohydrolase [Tateyamaria sp. ANG-S1].	78.90	109	23	0	13	121	4	112	3e-59	190
rs:WP_009818528	phosphoribosyl-AMP cyclohydrolase [Roseovarius sp. 217].	76.58	111	26	0	11	121	1	111	4e-59	190
rs:WP_007204869	phosphoribosyl-AMP cyclohydrolase [Loktanella vestfoldensis].	77.06	109	25	0	11	119	1	109	5e-59	190
sp:HIS3_RHOS5	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	72.03	118	33	0	11	128	1	118	6e-59	189
rs:WP_045982040	phosphoribosyl-AMP cyclohydrolase [Paracoccus sp. S4493].	71.54	123	34	1	6	128	2	123	6e-59	189
rs:WP_019296175	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Leisingera].	77.48	111	25	0	11	121	1	111	9e-59	189
sp:HIS3_RHOS1	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	71.19	118	34	0	11	128	1	118	1e-58	189
rs:WP_008282205	phosphoribosyl-AMP cyclohydrolase [Roseovarius sp. TM1035].	75.68	111	27	0	11	121	1	111	1e-58	189
sp:HIS3_DINSH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	72.97	111	30	0	11	121	1	111	1e-58	188
rs:WP_046000373	phosphoribosyl-AMP cyclohydrolase [Paracoccus sp. 361].	70.73	123	35	1	6	128	2	123	1e-58	189
rs:WP_043139212	phosphoribosyl-AMP cyclohydrolase [Ponticoccus sp. UMTAT08].	77.48	111	25	0	11	121	1	111	2e-58	188
rs:WP_009564339	phosphoribosyl-AMP cyclohydrolase [Rhodobacter sp. AKP1].	71.19	118	34	0	11	128	1	118	2e-58	188
rs:WP_039530599	phosphoribosyl-AMP cyclohydrolase [Ruegeria sp. ANG-S4].	78.90	109	23	0	13	121	7	115	2e-58	188
rs:WP_039145754	phosphoribosyl-AMP cyclohydrolase [Leisingera sp. ANG-DT].	76.58	111	26	0	11	121	1	111	3e-58	188
rs:WP_008561098	phosphoribosyl-AMP cyclohydrolase [Ruegeria sp. R11].	75.68	111	27	0	11	121	7	117	3e-58	188
rs:WP_037269653	phosphoribosyl-AMP cyclohydrolase [Roseovarius mucosus].	75.68	111	27	0	11	121	1	111	4e-58	187
rs:WP_042249245	phosphoribosyl-AMP cyclohydrolase [Paracoccus sp. PAMC 22219].	70.73	123	35	1	6	128	2	123	4e-58	187
rs:WP_007816118	phosphoribosyl-AMP cyclohydrolase [Roseobacter sp. AzwK-3b].	69.42	121	34	1	11	131	1	118	7e-58	187
sp:HIS3_ROSDO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	70.25	121	36	0	2	122	1	121	8e-58	187
rs:WP_028092155	phosphoribosyl-AMP cyclohydrolase [Donghicola xiamenensis].	75.68	111	27	0	11	121	1	111	8e-58	186
rs:WP_040168941	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Phaeobacter].	75.00	112	28	0	10	121	6	117	9e-58	187
rs:WP_024090277	phosphoribosyl-AMP cyclohydrolase [Leisingera methylohalidivorans].	71.43	119	34	0	10	128	4	122	1e-57	186
rs:WP_027240121	phosphoribosyl-AMP cyclohydrolase [Pseudophaeobacter arcticus].	73.21	112	30	0	11	122	7	118	1e-57	186
rs:WP_043918135	phosphoribosyl-AMP cyclohydrolase [Jannaschia aquimarina].	73.87	111	29	0	11	121	1	111	1e-57	186
sp:HIS3_RUEST	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	73.87	111	29	0	11	121	11	121	1e-57	186
rs:WP_013961866	phosphoribosyl-AMP cyclohydrolase [Roseobacter litoralis].	77.98	109	24	0	13	121	12	120	1e-57	186
rs:WP_024812525	phosphoribosyl-AMP cyclohydrolase [Oceanicola sp. HL-35].	74.77	111	28	0	11	121	1	111	3e-57	185
rs:WP_037279075	phosphoribosyl-AMP cyclohydrolase [Rubellimicrobium mesophilum].	74.56	114	29	0	11	124	1	114	3e-57	185
rs:WP_018301379	phosphoribosyl-AMP cyclohydrolase [Wenxinia marina].	75.23	109	27	0	13	121	2	110	3e-57	185
sp:HIS3_RHOS4	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	70.34	118	35	0	11	128	1	118	4e-57	185
rs:WP_022708268	phosphoribosyl-AMP cyclohydrolase [Paracoccus zeaxanthinifaciens].	77.57	107	24	0	13	119	2	108	4e-57	185
rs:WP_014879912	phosphoribosyl-AMP cyclohydrolase [Phaeobacter inhibens].	73.21	112	30	0	10	121	6	117	4e-57	185
rs:WP_039178207	phosphoribosyl-AMP cyclohydrolase [Leisingera sp. ANG-M7].	73.68	114	30	0	8	121	2	115	5e-57	185
rs:WP_027261363	phosphoribosyl-AMP cyclohydrolase [Sedimentitalea nanhaiensis].	72.97	111	30	0	11	121	1	111	7e-57	184
rs:WP_014874554	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Phaeobacter].	72.32	112	31	0	10	121	6	117	8e-57	184
rs:WP_025044633	phosphoribosyl-AMP cyclohydrolase [Sulfitobacter sp. MM-124].	76.15	109	26	0	11	119	1	109	1e-56	184
rs:WP_025312681	phosphoribosyl-AMP cyclohydrolase [Roseibacterium elongatum].	72.88	118	32	0	13	130	6	123	1e-56	184
sp:HIS3_PARDP	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	70.80	113	33	0	13	125	2	114	2e-56	183
rs:WP_025057493	phosphoribosyl-AMP cyclohydrolase [Sulfitobacter sp. NB-77].	74.31	109	28	0	11	119	1	109	2e-56	183
rs:WP_010138363	phosphoribosyl-AMP cyclohydrolase [Oceanicola sp. S124].	70.34	118	35	0	11	128	1	118	2e-56	183
rs:WP_009177218	phosphoribosyl-AMP cyclohydrolase [Silicibacter sp. TrichCH4B].	75.23	109	27	0	13	121	13	121	2e-56	183
tr:R0F611_9RHOB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	73.87	111	29	0	11	121	1	111	4e-56	182
rs:WP_007120440	phosphoribosyl-AMP cyclohydrolase [Oceanibulbus indolifex].	70.27	111	33	0	11	121	1	111	4e-56	182
rs:WP_027237462	phosphoribosyl-AMP cyclohydrolase [Leisingera caerulea].	73.21	112	30	0	10	121	4	115	5e-56	182
rs:WP_027258798	phosphoribosyl-AMP cyclohydrolase [Leisingera aquimarina].	75.00	112	28	0	10	121	4	115	6e-56	182
rs:WP_036754785	phosphoribosyl-AMP cyclohydrolase [Paracoccus versutus].	70.18	114	34	0	13	126	2	115	6e-56	182
rs:WP_036738834	phosphoribosyl-AMP cyclohydrolase [Paracoccus halophilus].	72.97	111	30	0	13	123	2	112	7e-56	182
rs:WP_008556160	phosphoribosyl-AMP cyclohydrolase [Rhodobacterales bacterium Y4I].	73.21	112	30	0	10	121	4	115	8e-56	182
rs:WP_009804625	phosphoribosyl-AMP cyclohydrolase [Oceanicola batsensis].	74.77	111	27	1	11	121	1	110	1e-55	181
rs:WP_007800226	phosphoribosyl-AMP cyclohydrolase [Pelagibaca bermudensis].	69.17	120	37	0	11	130	1	120	1e-55	181
rs:WP_042462036	phosphoribosyl-AMP cyclohydrolase [Rhodovulum sulfidophilum].	69.17	120	36	1	11	130	1	119	2e-55	181
rs:WP_027243817	phosphoribosyl-AMP cyclohydrolase [Leisingera daeponensis].	72.32	112	31	0	10	121	4	115	2e-55	181
rs:WP_022704491	phosphoribosyl-AMP cyclohydrolase [Pseudorhodobacter ferrugineus].	68.64	118	37	0	11	128	1	118	2e-55	180
rs:WP_008328922	phosphoribosyl-AMP cyclohydrolase [Maritimibacter alkaliphilus].	74.77	111	28	0	11	121	1	111	2e-55	181
rs:WP_040641419	phosphoribosyl-AMP cyclohydrolase [Ruegeria mobilis].	72.97	111	30	0	11	121	11	121	2e-55	181
rs:WP_028721045	phosphoribosyl-AMP cyclohydrolase [Paracoccus yeei].	68.42	114	36	0	13	126	2	115	3e-55	180
rs:WP_009571896	phosphoribosyl-AMP cyclohydrolase [Celeribacter baekdonensis].	74.31	109	28	0	11	119	1	109	3e-55	180
rs:WP_043842432	phosphoribosyl-AMP cyclohydrolase [Roseivivax atlanticus].	75.23	109	27	0	11	119	1	109	4e-55	180
rs:WP_028711233	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Paracoccus].	72.48	109	30	0	13	121	2	110	4e-55	179
rs:WP_036559243	phosphoribosyl-AMP cyclohydrolase [Oceanicola sp. MCTG156(1a)].	71.67	120	33	1	11	130	1	119	4e-55	179
rs:WP_009808494	phosphoribosyl-AMP cyclohydrolase [Roseobacter sp. MED193].	68.75	112	35	0	11	122	7	118	5e-55	179
rs:WP_036718385	phosphoribosyl-AMP cyclohydrolase [Paracoccus sphaerophysae].	73.39	109	29	0	13	121	2	110	5e-55	179
rs:WP_024844476	phosphoribosyl-AMP cyclohydrolase [Paracoccus pantotrophus].	69.91	113	34	0	13	125	2	114	5e-55	179
rs:WP_029371747	phosphoribosyl-AMP cyclohydrolase [Paracoccus sp. TRP].	70.69	116	34	0	11	126	1	116	6e-55	179
rs:WP_008884801	phosphoribosyl-AMP cyclohydrolase [Citreicella sp. SE45].	72.57	113	31	0	9	121	6	118	6e-55	179
rs:WP_037907342	phosphoribosyl-AMP cyclohydrolase [Sulfitobacter mediterraneus].	72.07	111	31	0	11	121	1	111	6e-55	179
rs:WP_020950932	phosphoribosyl-AMP cyclohydrolase [Paracoccus aminophilus].	72.48	109	30	0	13	121	2	110	6e-55	179
rs:WP_025048143	phosphoribosyl-AMP cyclohydrolase [Sulfitobacter mediterraneus].	72.07	111	31	0	11	121	1	111	6e-55	179
rs:WP_034453566	phosphoribosyl-AMP cyclohydrolase [Citreicella sp. 357].	72.97	111	30	0	11	121	1	111	6e-55	179
rs:WP_007427485	phosphoribosyl-AMP cyclohydrolase [Oceaniovalibus guishaninsula].	67.77	121	36	1	11	131	1	118	7e-55	179
rs:WP_045389605	phosphoribosyl-AMP cyclohydrolase [Falsirhodobacter sp. alg1].	66.12	121	38	1	11	131	1	118	7e-55	179
rs:WP_038077978	phosphoribosyl-AMP cyclohydrolase [Thioclava pacifica].	67.23	119	39	0	11	129	1	119	2e-54	178
rs:WP_021100472	phosphoribosyl-AMP cyclohydrolase [Litoreibacter arenae].	72.48	109	30	0	13	121	4	112	2e-54	177
tr:I1AR56_9RHOB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	72.07	111	31	0	11	121	2	112	3e-54	177
rs:WP_043869914	phosphoribosyl-AMP cyclohydrolase [Celeribacter indicus].	74.31	109	28	0	11	119	1	109	3e-54	177
rs:WP_020039961	phosphoribosyl-AMP cyclohydrolase [Salipiger mucosus].	66.67	120	40	0	11	130	1	120	3e-54	177
rs:WP_023923311	phosphoribosyl-AMP cyclohydrolase [Rhodobacter capsulatus].	68.33	120	38	0	11	130	1	120	3e-54	177
rs:WP_008031943	phosphoribosyl-AMP cyclohydrolase [Rhodobacter sp. SW2].	66.95	118	39	0	11	128	1	118	3e-54	177
rs:WP_026758994	phosphoribosyl-AMP cyclohydrolase [Sediminimonas qiaohouensis].	66.67	120	40	0	11	130	1	120	4e-54	177
rs:WP_025060764	phosphoribosyl-AMP cyclohydrolase [Sulfitobacter donghicola].	76.92	104	24	0	11	114	1	104	5e-54	177
rs:WP_022573831	phosphoribosyl-AMP cyclohydrolase [Rhodobacteraceae bacterium HIMB11].	74.55	110	28	0	11	120	1	110	5e-54	177
rs:WP_017997867	phosphoribosyl-AMP cyclohydrolase [Paracoccus sp. N5].	69.03	113	35	0	13	125	2	114	6e-54	177
rs:WP_037259670	phosphoribosyl-AMP cyclohydrolase [Roseivivax halodurans].	74.31	109	28	0	11	119	1	109	7e-54	176
rs:WP_037928812	phosphoribosyl-AMP cyclohydrolase [Sulfitobacter pseudonitzschiae].	73.83	107	28	0	13	119	6	112	9e-54	176
rs:WP_038145207	phosphoribosyl-AMP cyclohydrolase [Thioclava sp. 13D2W-2].	68.07	119	38	0	11	129	1	119	9e-54	176
rs:WP_043750635	phosphoribosyl-AMP cyclohydrolase [Oceanicola sp. 22II-S11g].	72.07	111	30	1	11	121	1	110	1e-53	176
rs:WP_007254479	phosphoribosyl-AMP cyclohydrolase [Oceanicola granulosus].	72.07	111	31	0	11	121	1	111	2e-53	175
rs:WP_013067393	phosphoribosyl-AMP cyclohydrolase [Rhodobacter capsulatus].	67.50	120	39	0	11	130	1	120	2e-53	176
rs:WP_023664008	phosphoribosyl-AMP cyclohydrolase [Rhodobacter sp. CACIA14H1].	67.80	118	38	0	11	128	1	118	2e-53	176
rs:WP_043768211	phosphoribosyl-AMP cyclohydrolase [Roseivivax isoporae].	72.97	111	30	0	11	121	1	111	2e-53	175
rs:WP_028957342	phosphoribosyl-AMP cyclohydrolase [Sulfitobacter sp. 20_GPM-1509m].	71.96	107	30	0	13	119	6	112	2e-53	175
rs:WP_023913185	phosphoribosyl-AMP cyclohydrolase [Rhodobacter capsulatus].	66.67	120	40	0	11	130	1	120	3e-53	175
rs:WP_009829023	phosphoribosyl-AMP cyclohydrolase [Rhodobacteraceae bacterium HTCC2083].	64.46	121	40	1	11	131	1	118	4e-53	174
rs:WP_015500025	phosphoribosyl-AMP cyclohydrolase [Octadecabacter antarcticus].	72.97	111	30	0	11	121	1	111	5e-53	174
rs:WP_028285942	phosphoribosyl-AMP cyclohydrolase [Oceanicola nanhaiensis].	66.10	118	40	0	11	128	1	118	6e-53	174
rs:WP_025052859	phosphoribosyl-AMP cyclohydrolase [Sulfitobacter sp. NB-68].	69.72	109	33	0	11	119	1	109	9e-53	174
rs:WP_023915828	phosphoribosyl-AMP cyclohydrolase, partial [Rhodobacter capsulatus].	70.27	111	33	0	11	121	1	111	9e-53	174
rs:WP_035844216	phosphoribosyl-AMP cyclohydrolase [Defluviimonas sp. 20V17].	67.24	116	38	0	13	128	2	117	9e-53	174
rs:WP_036710450	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Paracoccus].	69.72	109	33	0	13	121	2	110	2e-52	173
sp:HIS3_JANSC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	71.56	109	31	0	13	121	4	112	2e-52	173
rs:WP_036704031	phosphoribosyl-AMP cyclohydrolase [Paracoccus sp. 10990].	69.72	109	33	0	13	121	2	110	2e-52	173
tr:K2BIL2_9BACT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	68.64	118	37	0	11	128	1	118	2e-52	172
rs:WP_023850580	phosphoribosyl-AMP cyclohydrolase [Rhodobacteraceae bacterium PD-2].	74.53	106	27	0	11	116	1	106	2e-52	172
rs:WP_039017664	phosphoribosyl-AMP cyclohydrolase [Halocynthiibacter namhaensis].	62.81	121	42	1	11	131	1	118	3e-52	172
rs:WP_015495320	phosphoribosyl-AMP cyclohydrolase [Octadecabacter arcticus].	72.07	111	31	0	11	121	1	111	3e-52	172
rs:WP_025062017	phosphoribosyl-AMP cyclohydrolase [Sulfitobacter guttiformis].	69.64	112	34	0	11	122	1	112	4e-52	172
rs:WP_036634033	phosphoribosyl-AMP cyclohydrolase [Paenirhodobacter enshiensis].	65.83	120	41	0	11	130	1	120	4e-52	172
rs:WP_028029793	phosphoribosyl-AMP cyclohydrolase [Gemmobacter nectariphilus].	69.37	111	34	0	11	121	1	111	5e-52	172
rs:WP_037206582	phosphoribosyl-AMP cyclohydrolase [Rhodovulum sp. NI22].	70.27	111	32	1	11	121	1	110	5e-52	172
rs:WP_009160791	phosphoribosyl-AMP cyclohydrolase [Thalassobium sp. R2A62].	68.14	113	35	1	13	125	2	113	5e-52	172
rs:WP_038003438	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Thalassobacter].	66.10	118	40	0	11	128	1	118	2e-51	170
rs:WP_018631630	phosphoribosyl-AMP cyclohydrolase [Meganema perideroedes].	68.81	109	34	0	13	121	6	114	3e-51	170
rs:WP_036733893	phosphoribosyl-AMP cyclohydrolase [Paracoccus sp. 39524].	66.97	109	36	0	13	121	2	110	4e-51	169
rs:WP_020056208	hypothetical protein [alpha proteobacterium SCGC AAA015-O19].	69.09	110	34	0	12	121	3	112	4e-51	169
rs:WP_013384330	phosphoribosyl-AMP cyclohydrolase [Ketogulonicigenium vulgare].	71.70	106	30	0	11	116	1	106	5e-51	169
rs:WP_036181567	phosphoribosyl-AMP cyclohydrolase [Maribius sp. MOLA 401].	66.67	111	37	0	11	121	1	111	6e-51	169
rs:WP_035247502	phosphoribosyl-AMP cyclohydrolase [Actibacterium atlanticum].	69.37	111	33	1	11	121	1	110	6e-51	169
rs:WP_005857711	phosphoribosyl-AMP cyclohydrolase [Sagittula stellata].	72.64	106	29	0	11	116	1	106	6e-51	169
rs:WP_008185525	phosphoribosyl-AMP cyclohydrolase [Rhodobacteraceae bacterium HTCC2150].	70.64	109	32	0	11	119	1	109	7e-51	169
rs:WP_017928606	phosphoribosyl-AMP cyclohydrolase [Loktanella hongkongensis].	68.81	109	34	0	13	121	2	110	9e-51	169
tr:U2Z561_9RHOB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	67.89	109	35	0	13	121	4	112	2e-50	167
rs:WP_045320128	phosphoribosyl-AMP cyclohydrolase [Loktanella cinnabarina].	67.89	109	35	0	13	121	2	110	3e-50	167
rs:WP_039003600	phosphoribosyl-AMP cyclohydrolase [Halocynthiibacter sp. PAMC 20958].	70.64	109	31	1	11	119	1	108	5e-50	167
rs:WP_038068911	phosphoribosyl-AMP cyclohydrolase [Thioclava dalianensis].	67.57	111	36	0	11	121	1	111	5e-50	167
rs:WP_038129173	phosphoribosyl-AMP cyclohydrolase [Thioclava sp. DT23-4].	61.67	120	46	0	11	130	1	120	3e-49	165
rs:WP_035741100	phosphoribosyl-AMP cyclohydrolase [Haematobacter missouriensis].	64.71	119	41	1	7	125	4	121	5e-49	164
tr:A0A086YIW7_9RHOB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	67.26	113	36	1	13	125	2	113	8e-49	164
rs:WP_035257248	phosphoribosyl-AMP cyclohydrolase [Actibacterium mucosum].	65.25	118	37	2	2	119	1	114	9e-49	164
tr:A0A037ZKB5_9RHOB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	68.81	109	33	1	11	119	1	108	1e-48	163
rs:WP_035705939	phosphoribosyl-AMP cyclohydrolase [Haematobacter massiliensis].	60.80	125	46	1	7	131	4	125	2e-48	163
tr:A0A086YC73_9RHOB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	63.03	119	41	1	13	131	2	117	2e-48	162
rs:WP_035536665	phosphoribosyl-AMP cyclohydrolase [Hyphomonas oceanitis].	60.48	124	46	2	8	129	10	132	9e-48	161
tr:A0A059GAC2_9RHOB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	60.48	124	46	2	8	129	14	136	9e-48	161
rs:WP_046509805	phosphoribosyl-AMP cyclohydrolase [Kiloniella sp. P1-1].	63.72	113	41	0	9	121	4	116	2e-47	160
rs:WP_034793016	phosphoribosyl-AMP cyclohydrolase [Hyphomonas beringensis].	66.36	107	36	0	19	125	22	128	3e-47	160
tr:A0A062TTF3_9RHOB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	65.79	114	38	1	19	131	22	135	4e-47	160
rs:WP_034829387	phosphoribosyl-AMP cyclohydrolase [Hyphomonas sp. T16B2].	65.79	114	38	1	19	131	6	119	4e-47	159
rs:WP_034736893	phosphoribosyl-AMP cyclohydrolase [Hyphomonas chukchiensis].	62.16	111	42	0	19	129	4	114	4e-47	159
tr:A0A062UU06_9RHOB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	60.48	124	46	2	8	129	10	132	5e-47	159
rs:WP_036262849	phosphoribosyl-AMP cyclohydrolase [Mastigocoleus testarum].	64.29	112	38	1	19	130	4	113	8e-47	158
rs:WP_035601052	phosphoribosyl-AMP cyclohydrolase [Hyphomonas polymorpha].	65.22	115	37	2	8	120	10	123	8e-47	159
sp:HIS3_HYPNA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	64.91	114	37	2	8	119	10	122	3e-46	157
tr:A0A059E232_9RHOB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	68.63	102	31	1	19	119	22	123	3e-46	157
rs:WP_034817465	phosphoribosyl-AMP cyclohydrolase [Hyphomonas sp. L-53-1-40].	68.63	102	31	1	19	119	4	105	4e-46	157
rs:WP_020045395	hypothetical protein [alpha proteobacterium SCGC AAA298-K06].	60.34	116	46	0	11	126	1	116	9e-46	155
rs:WP_044049842	phosphoribosyl-AMP cyclohydrolase [Planktomarina temperata].	67.27	110	36	0	13	122	2	111	2e-45	155
rs:WP_034833938	phosphoribosyl-AMP cyclohydrolase [Inquilinus limosus].	61.95	113	43	0	18	130	10	122	6e-45	154
rs:WP_035617181	phosphoribosyl-AMP cyclohydrolase [Hyphomonas johnsonii].	60.71	112	44	0	19	130	22	133	6e-45	154
tr:A0A059FLV0_9RHOB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	60.71	112	44	0	19	130	26	137	6e-45	154
rs:WP_045699383	phosphoribosyl-AMP cyclohydrolase [Hyphomonas sp. BRH_c22].	62.04	108	41	0	19	126	15	122	9e-45	153
rs:WP_043115842	phosphoribosyl-AMP cyclohydrolase [Solemya velum gill symbiont].	61.82	110	40	1	17	126	24	131	1e-44	154
tr:A0A0B0HF68_SOVGS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	61.82	110	40	1	17	126	30	137	1e-44	154
rs:WP_034760987	phosphoribosyl-AMP cyclohydrolase [Hyphomonas sp. CY54-11-8].	66.96	112	34	2	8	117	10	120	2e-44	153
rs:WP_029939507	phosphoribosyl-AMP cyclohydrolase [Thiomicrospira sp. MA2-6].	54.96	131	57	1	2	130	1	131	2e-44	153
rs:WP_033423247	phosphoribosyl-ATP diphosphatase [Geopsychrobacter electrodiphilus].	71.88	96	27	0	18	113	8	103	3e-44	155
rs:WP_044563075	phosphoribosyl-AMP cyclohydrolase [Azospirillum sp. B4].	62.07	116	44	0	16	131	18	133	3e-44	153
rs:WP_040847037	phosphoribosyl-AMP cyclohydrolase [Nitrospirillum amazonense].	58.78	131	52	2	2	131	1	130	3e-44	153
rs:WP_024080363	phosphoribosyl-AMP cyclohydrolase [Magnetospirillum gryphiswaldense].	69.23	104	32	0	11	114	4	107	3e-44	152
rs:WP_045657371	phosphoribosyl-AMP cyclohydrolase [Hyphomonadaceae bacterium BRH_c29].	60.33	121	45	2	8	126	10	129	5e-44	152
rs:WP_016482972	phosphoribosyl-AMP cyclohydrolase [Chthonomonas calidirosea].	64.08	103	36	1	18	119	7	109	6e-44	151
tr:G1Y0J0_9PROT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	61.29	124	46	2	9	131	4	126	9e-44	151
rs:WP_035581150	phosphoribosyl-AMP cyclohydrolase [Hyphomonas jannaschiana].	65.18	112	36	2	8	117	10	120	1e-43	151
tr:A4TZE8_9PROT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	67.92	106	34	0	9	114	2	107	1e-43	151
rs:WP_007016937	phosphoribosyl-AMP cyclohydrolase [Bermanella marisrubri].	55.73	131	56	1	2	130	8	138	1e-43	151
rs:WP_026868924	phosphoribosyl-AMP cyclohydrolase [Inquilinus limosus].	60.18	113	45	0	18	130	10	122	1e-43	150
rs:WP_028303520	phosphoribosyl-AMP cyclohydrolase [Oceanospirillum maris].	55.64	133	53	2	4	130	9	141	1e-43	151
rs:WP_038070547	phosphoribosyl-AMP cyclohydrolase [Thiomicrospira kuenenii].	54.96	131	57	1	2	130	8	138	2e-43	151
rs:WP_035548836	phosphoribosyl-AMP cyclohydrolase [Hyphomonas atlantica].	63.55	107	39	0	19	125	22	128	2e-43	150
rs:WP_033069470	phosphoribosyl-AMP cyclohydrolase [Thalassospira australica].	64.22	109	39	0	18	126	12	120	3e-43	150
rs:WP_007090036	phosphoribosyl-AMP cyclohydrolase [Thalassospira xiamenensis].	63.21	106	39	0	18	123	14	119	3e-43	150
rs:WP_012843320	phosphoribosyl-AMP cyclohydrolase [Rhodothermus marinus].	68.32	101	31	1	18	117	10	110	3e-43	149
rs:WP_028487340	phosphoribosyl-AMP cyclohydrolase [Thiomicrospira chilensis].	54.96	131	57	1	2	130	9	139	4e-43	150
rs:WP_022727639	phosphoribosyl-AMP cyclohydrolase [Fodinicurvata sediminis].	63.81	105	38	0	16	120	19	123	4e-43	149
rs:WP_021097015	phosphoribosyl-AMP cyclohydrolase [Rubellimicrobium thermophilum].	66.34	101	34	0	13	113	2	102	4e-43	149
rs:WP_041522211	phosphoribosyl-AMP cyclohydrolase [Gilvimarinus agarilyticus].	60.55	109	43	0	15	123	24	132	7e-43	149
rs:WP_008890885	phosphoribosyl-AMP cyclohydrolase [Thalassospira profundimaris].	65.09	106	37	0	18	123	12	117	7e-43	149
rs:WP_022950439	phosphoribosyl-AMP cyclohydrolase [Leucothrix mucor].	67.29	107	34	1	18	124	23	128	7e-43	149
rs:WP_040726603	phosphoribosyl-AMP cyclohydrolase [Thiomicrospira sp. Kp2].	55.81	129	55	1	2	128	9	137	8e-43	149
rs:WP_028301973	phosphoribosyl-AMP cyclohydrolase [Oceanospirillum beijerinckii].	57.02	114	49	0	17	130	27	140	8e-43	149
rs:WP_022000408	phosphoribosyl-AMP cyclohydrolase [Acetobacter sp. CAG:977].	66.67	102	33	1	12	113	8	108	8e-43	148
rs:WP_029406658	phosphoribosyl-AMP cyclohydrolase [Thiomicrospira sp. Milos-T2].	53.49	129	58	1	2	128	13	141	8e-43	149
rs:WP_044828738	phosphoribosyl-AMP cyclohydrolase [Thalassospira sp. HJ].	65.09	106	37	0	18	123	12	117	9e-43	149
rs:WP_038134751	phosphoribosyl-AMP cyclohydrolase [Thiomicrospira sp. Milos-T1].	54.96	131	57	1	2	130	8	138	9e-43	149
rs:WP_043285297	phosphoribosyl-AMP cyclohydrolase, partial [Reyranella massiliensis].	61.82	110	42	0	11	120	1	110	1e-42	148
rs:WP_008033685	phosphoribosyl-AMP cyclohydrolase [Rhodobacterales bacterium HTCC2255].	56.14	114	50	0	13	126	4	117	1e-42	148
rs:WP_020560158	phosphoribosyl-AMP cyclohydrolase [Thiothrix flexilis].	66.35	104	35	0	14	117	7	110	1e-42	148
rs:WP_038414814	phosphoribosyl-AMP cyclohydrolase, partial [Pseudomonas cremoricolorata].	56.56	122	51	1	1	120	4	125	1e-42	148
sp:HIS3_THICR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.67	131	60	1	2	130	10	140	2e-42	148
rs:WP_037987686	phosphoribosyl-AMP cyclohydrolase [Thalassospira permensis].	63.21	106	39	0	18	123	16	121	2e-42	148
tr:C5JB44_9BACT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	65.69	102	35	0	18	119	11	112	2e-42	148
rs:WP_028877951	phosphoribosyl-AMP cyclohydrolase [Terasakiella pusilla].	59.35	123	48	2	6	128	3	123	2e-42	147
rs:WP_020056578	phosphoribosyl-AMP cyclohydrolase [alpha proteobacterium SCGC AAA076-C03].	56.14	114	50	0	13	126	4	117	2e-42	147
rs:WP_028488793	phosphoribosyl-AMP cyclohydrolase [Thiothrix lacustris].	62.83	113	42	0	18	130	15	127	2e-42	147
rs:WP_044618075	phosphoribosyl-AMP cyclohydrolase [Gynuella sunshinyii].	65.35	101	35	0	18	118	25	125	2e-42	147
tr:A0A0B8R8S3_9PROT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	63.55	107	38	1	15	120	9	115	2e-42	147
rs:WP_019015489	hypothetical protein [Elioraea tepidiphila].	64.71	102	36	0	18	119	20	121	3e-42	148
rs:WP_028704510	phosphoribosyl-AMP cyclohydrolase [Propionibacteriaceae bacterium P6A17].	63.54	96	35	0	18	113	7	102	3e-42	147
sp:HIS3_ALKEH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	54.89	133	57	2	2	131	5	137	3e-42	147
rs:WP_028874113	phosphoribosyl-AMP cyclohydrolase [Tepidiphilus margaritifer].	58.82	119	46	2	13	130	6	122	3e-42	147
rs:WP_040812893	phosphoribosyl-AMP cyclohydrolase, partial [marine gamma proteobacterium HTCC2080].	63.11	103	38	0	11	113	3	105	3e-42	146
rs:WP_018350808	hypothetical protein [Longispora albida].	64.08	103	37	0	14	116	44	146	3e-42	148
rs:WP_040199054	phosphoribosyl-ATP diphosphatase [Geoalkalibacter subterraneus].	65.05	103	36	0	18	120	7	109	3e-42	150
rs:WP_029910732	phosphoribosyl-AMP cyclohydrolase [Hydrogenovibrio marinus].	55.04	129	56	1	2	128	8	136	3e-42	147
tr:A0A066ZQQ3_HYDMR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	55.04	129	56	1	2	128	10	138	4e-42	147
rs:WP_022694250	phosphoribosyl-AMP cyclohydrolase [Ponticaulis koreensis].	61.90	105	39	1	19	123	21	124	4e-42	147
rs:WP_046860366	phosphoribosyl-AMP cyclohydrolase [Sedimenticola sp. SIP-G1].	66.00	100	34	0	17	116	21	120	4e-42	147
rs:WP_007023054	phosphoribosyl-AMP cyclohydrolase [Neptuniibacter caesariensis].	61.02	118	41	2	8	124	21	134	8e-42	146
rs:WP_014067576	phosphoribosyl-AMP cyclohydrolase [Rhodothermus marinus].	67.33	101	32	1	18	117	10	110	8e-42	146
rs:WP_027713742	phosphoribosyl-ATP diphosphatase [Desulfuromonas sp. TF].	64.76	105	37	0	18	122	7	111	9e-42	149
sp:HIS3_RHOCS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	58.93	112	46	0	16	127	11	122	9e-42	146
rs:WP_046504914	phosphoribosyl-AMP cyclohydrolase [Kiloniella sp. P1-1].	60.00	110	43	1	11	119	1	110	1e-41	145
rs:WP_022730553	phosphoribosyl-AMP cyclohydrolase [Thalassospira lucentensis].	63.21	106	39	0	18	123	12	117	1e-41	145
tr:A0A0D6PKI4_9PROT	SubName: Full=Phosphoribosyl AMP cyclohydrolase {ECO:0000313|EMBL:GAN81708.1};	57.38	122	51	1	11	131	1	122	1e-41	145
rs:WP_018282572	hypothetical protein [Gallionella sp. SCGC AAA018-N21].	61.06	113	44	0	18	130	5	117	2e-41	145
rs:WP_019894885	hypothetical protein [Thiomicrospira halophila].	60.18	113	45	0	18	130	29	141	2e-41	145
rs:WP_035673796	phosphoribosyl-AMP cyclohydrolase [Azospirillum brasilense].	58.62	116	48	0	16	131	20	135	2e-41	145
rs:WP_044426222	phosphoribosyl-AMP cyclohydrolase [Skermanella aerolata].	63.64	110	40	0	18	127	13	122	2e-41	145
rs:WP_020294893	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. CF161].	62.26	106	40	0	18	123	30	135	2e-41	145
rs:WP_019557177	hypothetical protein [Thiomicrospira arctica].	53.44	131	59	1	2	130	14	144	2e-41	145
rs:WP_009605142	phosphoribosyl-AMP cyclohydrolase [SAR116 cluster alpha proteobacterium HIMB100].	65.38	104	36	0	18	121	11	114	3e-41	145
rs:WP_008927224	phosphoribosyl-AMP cyclohydrolase [Alcanivorax hongdengensis].	55.73	131	50	2	2	126	1	129	3e-41	145
rs:WP_025323001	phosphoribosyl-AMP cyclohydrolase [Deferrisoma camini].	62.39	109	39	2	14	120	2	110	3e-41	145
rs:WP_038527789	phosphoribosyl-AMP cyclohydrolase [Azospirillum brasilense].	58.62	116	48	0	16	131	20	135	3e-41	145
sp:HIS3_PELTS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	62.16	111	41	1	11	120	1	111	3e-41	144
rs:WP_018876164	MULTISPECIES: hypothetical protein [Thioalkalivibrio].	63.30	109	40	0	18	126	23	131	3e-41	145
rs:WP_018866473	MULTISPECIES: hypothetical protein [Thioalkalivibrio].	63.30	109	40	0	18	126	23	131	3e-41	145
rs:WP_010628590	phosphoribosyl-AMP cyclohydrolase [Halomonas sp. KM-1].	57.39	115	49	0	16	130	24	138	4e-41	145
rs:WP_022230851	phosphoribosyl-ATP diphosphatase [Firmicutes bacterium CAG:41].	60.58	104	41	0	16	119	6	109	4e-41	147
rs:WP_014240428	phosphoribosyl-AMP cyclohydrolase [Azospirillum brasilense].	58.62	116	48	0	16	131	20	135	4e-41	145
tr:A0A086D428_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	61.95	113	42	1	10	121	18	130	4e-41	145
rs:WP_019562865	hypothetical protein [Thioalkalivibrio sp. ALMg2].	57.25	131	50	1	2	126	1	131	4e-41	145
rs:WP_035473484	phosphoribosyl-AMP cyclohydrolase [Gammaproteobacteria bacterium MFB021].	61.95	113	42	1	10	121	15	127	4e-41	145
tr:A4GIE4_9BACT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	64.76	105	36	1	17	120	10	114	4e-41	144
rs:WP_029006756	phosphoribosyl-AMP cyclohydrolase [Azospirillum halopraeferens].	59.17	120	49	0	9	128	4	123	4e-41	144
rs:WP_025225354	phosphoribosyl-AMP cyclohydrolase [Fimbriimonas ginsengisoli].	59.62	104	42	0	18	121	7	110	4e-41	144
rs:WP_026261375	phosphoribosyl-AMP cyclohydrolase [Kiloniella laminariae].	60.36	111	43	1	18	127	13	123	4e-41	144
rs:WP_040612308	phosphoribosyl-AMP cyclohydrolase [Roseomonas cervicalis].	63.55	107	38	1	19	124	9	115	5e-41	144
rs:WP_035723522	phosphoribosyl-AMP cyclohydrolase [Fodinicurvata fenggangensis].	62.38	101	38	0	16	116	19	119	5e-41	144
rs:WP_038081003	phosphoribosyl-AMP cyclohydrolase [Thioalkalivibrio sp. ARh3].	61.47	109	42	0	18	126	23	131	5e-41	145
tr:D5RRZ6_9PROT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	63.55	107	38	1	19	124	25	131	5e-41	144
rs:WP_029014428	phosphoribosyl-AMP cyclohydrolase [Niveispirillum irakense].	53.54	127	59	0	2	128	1	127	6e-41	144
rs:WP_026148265	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Thioalkalivibrio].	61.82	110	42	0	17	126	22	131	6e-41	144
rs:WP_026301087	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Thioalkalivibrio].	61.47	109	42	0	18	126	23	131	6e-41	144
tr:D3SFG2_THISK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	61.82	110	42	0	17	126	35	144	7e-41	145
rs:WP_024326390	phosphoribosyl-AMP cyclohydrolase [Thioalkalivibrio sp. AKL19].	57.25	131	50	1	2	126	1	131	7e-41	144
tr:A0Z8H5_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	66.32	95	32	0	19	113	4	98	7e-41	143
rs:WP_043109618	phosphoribosyl-AMP cyclohydrolase [endosymbiont of unidentified scaly snail isolate Monju].	53.54	127	55	2	2	126	5	129	7e-41	144
rs:WP_038070432	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Thioalkalivibrio].	62.39	109	41	0	18	126	23	131	7e-41	144
rs:WP_038044547	phosphoribosyl-AMP cyclohydrolase [Thioalkalivibrio sp. ALJ3].	61.47	109	42	0	18	126	23	131	7e-41	144
rs:WP_038040535	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Thioalkalivibrio].	61.47	109	42	0	18	126	23	131	8e-41	144
rs:WP_019583171	phosphoribosyl-AMP cyclohydrolase [Thioalkalivibrio sp. ALE16].	62.39	109	41	0	18	126	23	131	8e-41	144
sp:HIS3_ACICJ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	63.21	106	38	1	19	123	10	115	8e-41	143
rs:WP_026182199	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Thioalkalivibrio].	61.47	109	42	0	18	126	23	131	8e-41	144
rs:WP_022993742	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Alcanivorax].	54.76	126	53	2	3	126	6	129	8e-41	144
tr:S6CGQ6_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	53.54	127	55	2	2	126	7	131	9e-41	144
rs:WP_007151476	phosphoribosyl-AMP cyclohydrolase [Alcanivorax sp. DG881].	57.14	126	50	2	3	126	6	129	9e-41	144
rs:WP_026345000	phosphoribosyl-AMP cyclohydrolase [Novispirillum itersonii].	60.00	110	44	0	10	119	6	115	9e-41	144
rs:WP_025898581	phosphoribosyl-AMP cyclohydrolase [Sneathiella glossodoripedis].	59.82	112	44	1	18	128	11	122	9e-41	143
rs:WP_018168540	hypothetical protein [Thioalkalivibrio sp. ALMg9].	57.25	131	50	1	2	126	1	131	1e-40	144
sp:HIS3_ALCBS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	57.14	126	50	2	3	126	6	129	1e-40	144
rs:WP_018874580	MULTISPECIES: hypothetical protein [Thioalkalivibrio].	64.22	109	39	0	18	126	23	131	1e-40	144
rs:WP_028490891	phosphoribosyl-AMP cyclohydrolase [Thioalkalivibrio sp. ALJ15].	61.47	109	42	0	18	126	23	131	1e-40	144
rs:WP_028097413	phosphoribosyl-AMP cyclohydrolase [Dongia sp. URHE0060].	62.14	103	39	0	18	120	10	112	1e-40	143
rs:WP_008046309	phosphoribosyl-AMP cyclohydrolase [Reinekea blandensis].	53.54	127	57	1	3	127	6	132	1e-40	143
rs:WP_007422206	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Acidiphilium].	63.21	106	38	1	19	123	10	115	1e-40	143
rs:WP_018144410	MULTISPECIES: hypothetical protein [Thioalkalivibrio].	57.25	131	50	1	2	126	1	131	1e-40	144
rs:WP_019643023	hypothetical protein [Thioalkalivibrio sp. ALSr1].	59.29	113	46	0	18	130	23	135	1e-40	144
rs:WP_035757726	hypothetical protein, partial [Arthrobacter albus].	62.00	100	38	0	13	112	16	115	1e-40	143
rs:WP_022249354	hypothetical protein [Eubacterium sp. CAG:274].	64.36	101	36	0	18	118	5	105	1e-40	142
rs:WP_018141679	hypothetical protein [Thioalkalivibrio sp. ALJ7].	64.22	109	39	0	18	126	23	131	1e-40	144
rs:WP_018288721	hypothetical protein [zeta proteobacterium SCGC AB-602-C20].	63.54	96	35	0	18	113	7	102	1e-40	142
rs:WP_035657862	imidazole glycerol phosphate synthase [Lachnospiraceae bacterium AC2031].	56.41	117	49	1	16	130	15	131	1e-40	145
rs:WP_018877921	phosphoribosyl-AMP cyclohydrolase [Thioalkalivibrio sp. ALE28].	62.39	109	41	0	18	126	23	131	1e-40	143
rs:WP_036300950	phosphoribosyl-AMP cyclohydrolase [Methylomarinum vadi].	61.47	109	40	1	18	126	23	129	2e-40	143
rs:WP_045774332	phosphoribosyl-AMP cyclohydrolase [Elstera litoralis].	67.01	97	32	0	18	114	13	109	2e-40	143
rs:WP_019589560	MULTISPECIES: hypothetical protein [Thioalkalivibrio].	59.29	113	46	0	18	130	23	135	2e-40	143
rs:WP_019022350	hypothetical protein [Thioalkalivibrio sp. ALE23].	59.29	113	46	0	18	130	23	135	2e-40	143
rs:WP_027340848	phosphoribosyl-ATP pyrophosphatase [Halonatronum saccharophilum].	60.38	106	42	0	16	121	4	109	2e-40	145
rs:WP_018872087	hypothetical protein [Thioalkalivibrio sp. ALJ16].	69.00	100	31	0	18	117	23	122	2e-40	143
rs:WP_035233143	phosphoribosyl-AMP cyclohydrolase [Alcanivorax sp. 19-m-6].	55.73	131	50	2	2	126	1	129	2e-40	142
rs:WP_017941522	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Thioalkalivibrio].	62.39	109	41	0	18	126	23	131	2e-40	143
rs:WP_008943546	phosphoribosyl-AMP cyclohydrolase [Oceanibaculum indicum].	65.05	103	36	0	17	119	8	110	3e-40	142
rs:WP_034969996	phosphoribosyl-AMP cyclohydrolase [Corynebacterium jeikeium].	57.14	112	45	1	4	112	6	117	3e-40	142
rs:WP_034980725	phosphoribosyl-AMP cyclohydrolase [Corynebacterium jeikeium].	57.14	112	45	1	4	112	6	117	3e-40	142
sp:HIS3_MAGSM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	57.52	113	48	0	14	126	6	118	3e-40	142
rs:WP_013332355	phosphoribosyl-AMP cyclohydrolase [Halomonas elongata].	54.14	133	55	1	4	130	6	138	3e-40	142
rs:WP_024329161	phosphoribosyl-AMP cyclohydrolase [Thioalkalivibrio sp. ALR17-21].	59.29	113	46	0	18	130	23	135	3e-40	142
rs:WP_040541100	phosphoribosyl-AMP cyclohydrolase [marine gamma proteobacterium HTCC2148].	60.19	108	43	0	18	125	19	126	4e-40	142
rs:WP_022447081	phosphoribosyl-AMP cyclohydrolase [Faecalibacterium sp. CAG:74].	62.26	106	38	1	11	116	1	104	4e-40	144
rs:WP_043316301	phosphoribosyl-AMP cyclohydrolase [Microbulbifer sp. HZ11].	60.38	106	42	0	18	123	27	132	4e-40	142
rs:WP_018936189	hypothetical protein [Thioalkalivibrio sp. ALJ24].	59.29	113	46	0	18	130	23	135	5e-40	142
rs:WP_039735644	phosphoribosyl-AMP cyclohydrolase [Komagataeibacter intermedius].	63.89	108	38	1	18	124	18	125	5e-40	142
rs:WP_034977411	phosphoribosyl-AMP cyclohydrolase [Corynebacterium jeikeium].	64.21	95	34	0	18	112	23	117	5e-40	141
rs:WP_020394744	hypothetical protein [Thiothrix disciformis].	65.66	99	34	0	18	116	16	114	5e-40	142
sp:HIS3_CORJK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	64.21	95	34	0	18	112	27	121	5e-40	141
rs:WP_019625433	hypothetical protein [Thioalkalivibrio sp. ALJT].	64.49	107	38	0	18	124	23	129	5e-40	142
rs:WP_005295832	phosphoribosyl-AMP cyclohydrolase [Corynebacterium jeikeium].	64.21	95	34	0	18	112	19	113	5e-40	141
rs:WP_008621803	phosphoribosyl-AMP cyclohydrolase [Magnetospirillum sp. SO-1].	68.04	97	31	0	18	114	13	109	5e-40	141
rs:WP_025286459	phosphoribosyl-AMP cyclohydrolase [Granulibacter bethesdensis].	67.71	96	31	0	18	113	8	103	5e-40	141
rs:WP_037563415	phosphoribosyl-AMP cyclohydrolase [Spirochaeta sp. JC202].	58.72	109	44	1	23	130	10	118	6e-40	141
rs:WP_041626342	phosphoribosyl-AMP cyclohydrolase [Corynebacterium jeikeium].	64.21	95	34	0	18	112	5	99	6e-40	140
tr:B7RXC3_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	60.19	108	43	0	18	125	38	145	6e-40	142
rs:WP_035005420	phosphoribosyl-AMP cyclohydrolase [Corynebacterium jeikeium].	64.21	95	34	0	18	112	23	117	6e-40	141
rs:WP_018149201	hypothetical protein [Henriciella marina].	64.29	98	35	0	19	116	22	119	7e-40	141
sp:HIS3_BORBR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	61.26	111	39	2	20	126	13	123	7e-40	141
rs:WP_002709233	phosphoribosyl-AMP cyclohydrolase [Thiothrix nivea].	57.89	114	48	0	17	130	10	123	8e-40	141
rs:WP_035009047	phosphoribosyl-AMP cyclohydrolase [Corynebacterium jeikeium].	64.21	95	34	0	18	112	5	99	8e-40	140
rs:WP_018947679	hypothetical protein [Thioalkalivibrio sp. AKL17].	57.89	114	48	0	18	131	23	136	8e-40	141
rs:WP_028491722	phosphoribosyl-AMP cyclohydrolase [Thioalkalivibrio sp. ALE19].	57.89	114	48	0	18	131	23	136	8e-40	141
rs:WP_033468242	phosphoribosyl-AMP cyclohydrolase [Bordetella bronchiseptica].	61.26	111	39	2	20	126	13	123	8e-40	141
rs:WP_028878413	phosphoribosyl-AMP cyclohydrolase [Terasakiella pusilla].	59.29	113	46	0	16	128	13	125	8e-40	141
rs:WP_019595048	hypothetical protein [Thioalkalivibrio sp. ALM2T].	56.49	131	51	1	2	126	1	131	8e-40	141
tr:A0A094NXW1_9ZZZZ	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGA03820.1};	61.62	99	38	0	19	117	11	109	9e-40	140
rs:WP_038059932	phosphoribosyl-AMP cyclohydrolase [Thioalkalivibrio sp. AKL11].	62.39	109	41	0	18	126	23	131	9e-40	141
rs:WP_026214446	phosphoribosyl-AMP cyclohydrolase [Nonomuraea coxensis].	67.37	95	31	0	18	112	14	108	9e-40	140
rs:WP_018649809	hypothetical protein [Thioalkalivibrio sp. ALMg3].	59.50	121	43	1	2	116	1	121	1e-39	141
rs:WP_041071175	phosphoribosyl-AMP cyclohydrolase [Thiolapillus brandeum].	55.83	120	51	1	7	126	8	125	1e-39	141
rs:WP_018176011	MULTISPECIES: hypothetical protein [Thioalkalivibrio].	59.50	121	43	1	2	116	1	121	1e-39	141
rs:WP_019567971	MULTISPECIES: hypothetical protein [Thioalkalivibrio].	59.50	121	43	1	2	116	1	121	1e-39	141
rs:WP_027874968	phosphoribosyl-AMP cyclohydrolase [Spongiibacter marinus].	53.54	127	57	1	2	126	9	135	1e-39	141
rs:WP_018003182	hypothetical protein [Verrucomicrobia bacterium SCGC AB-629-E09].	54.39	114	52	0	17	130	6	119	1e-39	140
rs:WP_034972131	phosphoribosyl-AMP cyclohydrolase [Corynebacterium jeikeium].	56.25	112	46	1	4	112	6	117	1e-39	140
rs:WP_044629112	phosphoribosyl-AMP cyclohydrolase [Halomonas meridiana].	60.18	113	45	0	18	130	35	147	1e-39	141
rs:WP_034986668	phosphoribosyl-AMP cyclohydrolase [Corynebacterium jeikeium].	64.21	95	34	0	18	112	5	99	1e-39	140
rs:WP_018870556	MULTISPECIES: hypothetical protein [Thioalkalivibrio].	57.89	114	48	0	18	131	23	136	1e-39	141
rs:WP_014993262	phosphoribosyl-AMP cyclohydrolase [Alcanivorax dieselolei].	53.97	126	54	2	3	126	6	129	1e-39	140
rs:WP_026278822	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Thioalkalivibrio].	60.55	109	43	0	18	126	23	131	1e-39	141
rs:WP_029135728	phosphoribosyl-AMP cyclohydrolase [Nakamurella lactea].	63.00	100	37	0	13	112	9	108	1e-39	140
tr:A0A094SLN0_9ZZZZ	SubName: Full=Phosphoribosyl-AMP cyclohydrolase family protein {ECO:0000313|EMBL:KGA19433.1};	64.89	94	33	0	21	114	16	109	1e-39	140
rs:WP_033356930	phosphoribosyl-AMP cyclohydrolase [Dactylosporangium aurantiacum].	60.78	102	40	0	18	119	16	117	2e-39	140
rs:WP_045818413	phosphoribosyl-AMP cyclohydrolase [Teredinibacter sp. 1162T.S.0a.05].	54.87	113	51	0	18	130	7	119	2e-39	140
tr:W0TSS8_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	55.83	120	51	1	7	126	17	134	2e-39	140
rs:WP_043638770	phosphoribosyl-AMP cyclohydrolase [Nonomuraea candida].	67.37	95	31	0	18	112	14	108	2e-39	140
rs:WP_034991775	phosphoribosyl-AMP cyclohydrolase [Corynebacterium jeikeium].	56.25	112	46	1	4	112	6	117	2e-39	140
rs:WP_007434586	phosphoribosyl-AMP cyclohydrolase [Acetobacteraceae bacterium AT-5844].	62.38	101	38	0	19	119	22	122	2e-39	140
rs:WP_013836005	phosphoribosyl-AMP cyclohydrolase [Thioalkalimicrobium cyclicum].	57.76	116	49	0	16	131	26	141	2e-39	141
sp:HIS3_HALHL	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	57.52	113	46	1	7	117	10	122	2e-39	140
rs:WP_041535095	phosphoribosyl-AMP cyclohydrolase, partial [Parvularcula bermudensis].	60.58	104	41	0	14	117	14	117	2e-39	140
rs:WP_045637544	phosphoribosyl-AMP cyclohydrolase [Peptococcaceae bacterium BRH_c4a].	55.65	115	51	0	11	125	1	115	2e-39	140
gpu:CP011267_920	phosphoribosyl-AMP cyclohydrolase [Geoglobus ahangari]	63.00	100	37	0	18	117	3	102	2e-39	139
rs:WP_043335121	phosphoribosyl-AMP cyclohydrolase [Belnapia moabensis].	62.14	103	39	0	17	119	4	106	2e-39	140
rs:WP_025438665	phosphoribosyl-AMP cyclohydrolase [Komagataeibacter xylinus].	62.04	108	40	1	18	124	18	125	2e-39	140
rs:WP_022664795	phosphoribosyl-AMP cyclohydrolase [Desulfospira joergensenii].	56.03	116	44	2	10	124	3	112	2e-39	140
rs:WP_018950319	phosphoribosyl-AMP cyclohydrolase [Thioalkalivibrio sp. ALMg11].	56.49	131	51	1	2	126	1	131	2e-39	140
rs:WP_015423502	phosphoribosyl-AMP cyclohydrolase [uncultured Termite group 1 bacterium].	58.33	108	44	1	11	117	1	108	2e-39	140
rs:WP_037256715	phosphoribosyl-AMP cyclohydrolase, partial [Rhodovibrio salinarum].	68.89	90	28	0	24	113	28	117	2e-39	139
tr:E0TBN2_PARBH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	60.58	104	41	0	14	117	10	113	2e-39	140
rs:WP_027961082	phosphoribosyl-AMP cyclohydrolase [Halomonas halodenitrificans].	59.81	107	43	0	18	124	26	132	2e-39	140
rs:WP_015145311	phosphoribosyl-AMP cyclohydrolase [Pleurocapsa minor].	64.00	100	35	1	18	116	11	110	3e-39	139
rs:WP_020209954	hypothetical protein [Gilvimarinus chinensis].	59.43	106	43	0	18	123	25	130	3e-39	140
rs:WP_005270507	hypothetical protein [Acinetobacter sp. NIPH 1859].	61.11	108	40	1	8	113	16	123	3e-39	140
rs:WP_043831509	phosphoribosyl-AMP cyclohydrolase, partial [Roseomonas aerilata].	65.98	97	33	0	16	112	11	107	3e-39	140
rs:WP_027829775	phosphoribosyl-AMP cyclohydrolase [Marinobacter sp. HL-58].	60.19	103	40	1	18	119	17	119	3e-39	140
tr:A0A0D6P717_9PROT	SubName: Full=Phosphoribosyl AMP cyclohydrolase {ECO:0000313|EMBL:GAN76649.1};	66.02	103	35	0	18	120	11	113	3e-39	140
rs:WP_012136970	phosphoribosyl-AMP cyclohydrolase [Marinobacter lipolyticus].	56.14	114	49	1	18	130	17	130	3e-39	140
rs:WP_043363651	phosphoribosyl-AMP cyclohydrolase [Belnapia sp. F-4-1].	61.17	103	40	0	17	119	9	111	3e-39	139
rs:WP_019086412	phosphoribosyl-AMP cyclohydrolase [Komagataeibacter europaeus].	62.04	108	40	1	18	124	18	125	3e-39	140
rs:WP_028084906	phosphoribosyl-AMP cyclohydrolase [Dolichospermum circinale].	64.71	102	35	1	17	117	4	105	3e-39	139
rs:WP_041546623	phosphoribosyl-AMP cyclohydrolase [Nocardioides sp. JS614].	58.18	110	46	0	18	127	22	131	3e-39	139
rs:WP_018084799	hypothetical protein [Desulfurispora thermophila].	54.62	119	53	1	13	130	4	122	3e-39	139
rs:WP_029457100	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio alcoholivorans].	61.82	110	40	2	23	130	10	119	3e-39	139
rs:WP_010507791	phosphoribosyl-AMP cyclohydrolase [Komagataeibacter europaeus].	62.96	108	39	1	18	124	18	125	3e-39	140
rs:WP_010513534	phosphoribosyl-AMP cyclohydrolase [Komagataeibacter oboediens].	62.04	108	40	1	18	124	18	125	3e-39	139
tr:A0A0D6QAN8_KOMXY	SubName: Full=Phosphoribosyl AMP cyclohydrolase {ECO:0000313|EMBL:GAO00485.1};	62.04	108	40	1	18	124	18	125	4e-39	139
rs:WP_017903024	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fuscovaginae].	60.58	104	41	0	17	120	29	132	4e-39	140
rs:WP_019091619	phosphoribosyl-AMP cyclohydrolase [Komagataeibacter europaeus].	62.96	108	39	1	18	124	18	125	4e-39	139
gpu:CP009498_424	Phosphoribosyl-AMP cyclohydrolase [Candidatus Endomicrobium sp. Rsa215]	54.31	116	52	1	11	125	1	116	4e-39	139
rs:WP_014247893	phosphoribosyl-AMP cyclohydrolase [Azospirillum lipoferum].	61.54	104	40	0	16	119	17	120	4e-39	139
rs:WP_025320781	phosphoribosyl-AMP cyclohydrolase [Granulibacter bethesdensis].	66.67	96	32	0	18	113	8	103	4e-39	139
rs:WP_022342468	phosphoribosyl-ATP diphosphatase [Roseburia sp. CAG:309].	64.76	105	35	1	9	113	207	309	4e-39	146
rs:WP_011395624	phosphoribosyl-AMP cyclohydrolase [Hahella chejuensis].	58.49	106	44	0	18	123	27	132	4e-39	139
rs:WP_028645669	phosphoribosyl-AMP cyclohydrolase [Nocardioides sp. URHA0020].	65.26	95	33	0	18	112	12	106	4e-39	139
rs:WP_040284879	phosphoribosyl-AMP cyclohydrolase [Tessaracoccus sp. SIT6].	62.89	97	36	0	18	114	6	102	4e-39	138
sp:HIS3_NOCSJ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	58.72	109	45	0	18	126	12	120	5e-39	139
sp:HIS3_BORPE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	60.36	111	40	2	20	126	13	123	5e-39	139
rs:WP_008160455	phosphoribosyl-AMP cyclohydrolase [Achromobacter arsenitoxydans].	58.56	111	42	2	20	126	13	123	5e-39	139
rs:WP_046017268	phosphoribosyl-AMP cyclohydrolase [Marinomonas sp. S3726].	55.65	115	49	1	6	118	10	124	5e-39	139
rs:WP_009851109	phosphoribosyl-AMP cyclohydrolase [Mariprofundus ferrooxydans].	60.78	102	40	0	18	119	13	114	5e-39	139
tr:A0A0D6PXJ3_KOMEU	SubName: Full=Phosphoribosyl AMP cyclohydrolase {ECO:0000313|EMBL:GAN96047.1};	62.96	108	39	1	18	124	18	125	6e-39	139
rs:WP_025826033	phosphoribosyl-AMP cyclohydrolase [Acetobacter okinawensis].	56.64	113	49	0	1	113	1	113	6e-39	139
rs:WP_035569517	phosphoribosyl-AMP cyclohydrolase [Hyphomonas adhaerens].	64.66	116	37	3	8	120	10	124	6e-39	139
rs:WP_025319099	phosphoribosyl-AMP cyclohydrolase [Granulibacter bethesdensis].	63.11	103	37	1	18	119	8	110	6e-39	139
sp:HIS3_GRABC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	65.62	96	33	0	18	113	8	103	6e-39	139
rs:WP_021058105	phosphoribosyl-AMP cyclohydrolase [Haloquadratum sp. J07HQX50].	57.69	104	44	0	15	118	6	109	6e-39	139
rs:WP_013412178	phosphoribosyl-ATP pyrophosphatase [Caldicellulosiruptor owensensis].	52.99	117	55	0	14	130	3	119	6e-39	141
rs:WP_003623988	phosphoribosyl-AMP cyclohydrolase [Acetobacter pasteurianus].	54.17	120	54	1	6	124	6	125	6e-39	139
rs:WP_034389874	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Proteobacteria].	58.41	113	47	0	18	130	35	147	6e-39	139
tr:A0A0D6SVT9_9PSED	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:KIV72448.1}; EC=3.5.4.19 {ECO:0000313|EMBL:KIV72448.1};	50.40	125	60	1	2	124	7	131	7e-39	140
rs:WP_029131944	phosphoribosyl-AMP cyclohydrolase [Sedimenticola selenatireducens].	63.00	100	37	0	17	116	22	121	7e-39	139
rs:WP_025813741	phosphoribosyl-AMP cyclohydrolase [Komagataeibacter kakiaceti].	62.96	108	39	1	18	124	18	125	7e-39	139
tr:U2S3R6_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.76	116	44	1	16	126	26	141	8e-39	139
rs:WP_042795709	phosphoribosyl-AMP cyclohydrolase [Achromobacter xylosoxidans].	58.56	111	42	2	20	126	13	123	8e-39	139
rs:XP_005712120	unnamed protein product [Chondrus crispus].	53.54	127	57	1	7	131	107	233	8e-39	142
rs:WP_007400453	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Acetobacteraceae].	59.13	115	46	1	18	131	18	132	8e-39	139
rs:WP_045582150	phosphoribosyl-AMP cyclohydrolase [Azospirillum thiophilum].	57.52	113	48	0	7	119	8	120	8e-39	139
rs:WP_046021647	phosphoribosyl-AMP cyclohydrolase [Magnetospira sp. QH-2].	61.17	103	40	0	17	119	10	112	8e-39	138
rs:WP_005998546	phosphoribosyl-ATP pyrophosphatase [Desulfuromonas acetoxidans].	60.40	101	40	0	18	118	7	107	8e-39	141
rs:WP_043545041	phosphoribosyl-AMP cyclohydrolase [Achromobacter sp. RTa].	59.46	111	41	2	20	126	13	123	9e-39	138
rs:WP_035244942	phosphoribosyl-AMP cyclohydrolase [Alcanivorax jadensis].	56.35	126	51	2	3	126	6	129	9e-39	139
rs:WP_029311792	phosphoribosyl-AMP cyclohydrolase [Acidiphilium angustum].	56.60	106	46	0	16	121	7	112	9e-39	138
rs:WP_021985546	phosphoribosyl-AMP cyclohydrolase [Clostridium sp. CAG:127].	62.24	98	37	0	16	113	43	140	9e-39	139
tr:A0A0D6NVB8_9PROT	SubName: Full=Phosphoribosyl AMP cyclohydrolase {ECO:0000313|EMBL:GAN70102.1};	56.64	113	49	0	1	113	1	113	1e-38	139
rs:WP_027717816	phosphoribosyl-ATP pyrophosphatase [Desulfovirgula thermocuniculi].	59.63	109	44	0	13	121	5	113	1e-38	141
rs:WP_015005957	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Cycloclasticus].	57.41	108	46	0	18	125	27	134	1e-38	139
rs:WP_036957575	phosphoribosyl-AMP cyclohydrolase [Propionibacterium granulosum].	61.62	99	38	0	18	116	5	103	1e-38	138
rs:WP_028669686	phosphoribosyl-AMP cyclohydrolase [Saccharospirillum impatiens].	54.40	125	53	2	3	125	6	128	1e-38	138
rs:WP_042787577	phosphoribosyl-AMP cyclohydrolase [Acetobacter aceti].	57.14	119	48	2	9	124	7	125	1e-38	138
rs:WP_009670991	phosphoribosyl-AMP cyclohydrolase [gamma proteobacterium IMCC1989].	59.09	110	44	1	18	127	27	135	1e-38	138
rs:WP_006388052	phosphoribosyl-AMP cyclohydrolase [Achromobacter xylosoxidans].	58.56	111	42	2	20	126	13	123	1e-38	138
rs:WP_022740188	phosphoribosyl-ATP diphosphatase [Adlercreutzia equolifaciens].	60.40	101	40	0	13	113	1	101	1e-38	137
rs:WP_031383531	phosphoribosyl-AMP cyclohydrolase [Halomonas zincidurans].	62.38	101	38	0	17	117	25	125	1e-38	139
rs:WP_006224533	phosphoribosyl-AMP cyclohydrolase [Achromobacter piechaudii].	58.56	111	42	2	20	126	13	123	1e-38	138
rs:WP_022983728	phosphoribosyl-AMP cyclohydrolase [Alcanivorax sp. P2S70].	59.29	113	44	1	3	113	6	118	1e-38	138
rs:WP_006460805	phosphoribosyl-AMP cyclohydrolase [Thioalkalimicrobium aerophilum].	55.46	119	53	0	13	131	23	141	1e-38	139
tr:E1YLC7_9DELT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	61.47	109	40	2	17	123	16	124	1e-38	138
rs:WP_025139940	phosphoribosyl-AMP cyclohydrolase [Achromobacter sp. DH1f].	58.56	111	42	2	20	126	13	123	1e-38	138
rs:WP_045645735	phosphoribosyl-ATP pyrophosphatase [Peptococcaceae bacterium BRH_c4b].	59.43	106	43	0	11	116	1	106	1e-38	141
rs:WP_046078673	phosphoribosyl-AMP cyclohydrolase [Halomonas sp. HG01].	52.76	127	54	1	4	124	6	132	1e-38	138
rs:WP_034124216	phosphoribosyl-ATP pyrophosphatase [Peptococcaceae bacterium BICA1-7].	53.72	121	55	1	11	130	1	121	1e-38	141
rs:WP_027858346	phosphoribosyl-AMP cyclohydrolase [Marinobacterium jannaschii].	58.65	104	42	1	16	118	7	110	1e-38	137
rs:WP_020932552	phosphoribosyl-AMP cyclohydrolase [Cycloclasticus zancles].	62.00	100	38	0	18	117	27	126	2e-38	138
rs:WP_006392327	phosphoribosyl-AMP cyclohydrolase [Achromobacter insuavis].	57.52	113	44	2	18	126	11	123	2e-38	138
rs:WP_043319978	phosphoribosyl-AMP cyclohydrolase [Microbulbifer sp. HZ11].	53.66	123	55	2	9	130	2	123	2e-38	138
rs:WP_010833371	phosphoribosyl-AMP cyclohydrolase [Nocardioides sp. CF8].	64.21	95	34	0	18	112	12	106	2e-38	137
rs:WP_009724413	phosphoribosyl-AMP cyclohydrolase [Halomonas sp. TD01].	57.52	113	48	0	18	130	35	147	2e-38	139
rs:WP_038337564	phosphoribosyl-AMP cyclohydrolase [zeta proteobacterium SCGC AB-133-C04].	59.18	98	40	0	16	113	5	102	2e-38	137
rs:WP_040363729	phosphoribosyl-AMP cyclohydrolase [Commensalibacter intestini].	57.14	112	48	0	8	119	3	114	2e-38	137
rs:WP_019088307	phosphoribosyl-AMP cyclohydrolase [Acetobacter pasteurianus].	53.33	120	55	1	6	124	6	125	2e-38	138
rs:WP_009867723	phosphoribosyl-AMP cyclohydrolase [Magnetospirillum magnetotacticum].	63.64	99	36	0	16	114	11	109	2e-38	137
rs:WP_017842442	phosphoribosyl-AMP cyclohydrolase [Methylomicrobium buryatense].	63.64	99	36	0	18	116	23	121	2e-38	138
rs:WP_014147319	phosphoribosyl-AMP cyclohydrolase [Methylomicrobium alcaliphilum].	63.64	99	36	0	18	116	23	121	2e-38	138
rs:WP_026351696	phosphoribosyl-AMP cyclohydrolase [Kushneria aurantia].	53.49	129	54	1	2	124	1	129	2e-38	138
rs:WP_008939549	phosphoribosyl-AMP cyclohydrolase [Marinobacter santoriniensis].	60.19	103	40	1	18	119	14	116	2e-38	137
tr:A0A0D6FH03_ALCXX	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:CKG69781.1};	58.56	111	42	2	20	126	13	123	2e-38	137
rs:WP_016854923	phosphoribosyl-AMP cyclohydrolase [Halomonas smyrnensis].	52.76	127	54	1	4	124	6	132	2e-38	138
tr:E5XEI8_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	60.19	108	41	1	9	116	147	252	2e-38	143
rs:WP_040100286	phosphoribosyl-ATP diphosphatase [Geoalkalibacter ferrihydriticus].	63.54	96	35	0	18	113	7	102	2e-38	140
rs:WP_019937572	phosphoribosyl-AMP cyclohydrolase [Bordetella sp. FB-8].	58.26	115	44	2	16	126	19	133	2e-38	138
rs:WP_029933655	phosphoribosyl-AMP cyclohydrolase [Thiomicrospira pelophila].	56.64	113	49	0	18	130	27	139	2e-38	138
rs:WP_006216831	phosphoribosyl-AMP cyclohydrolase [Achromobacter piechaudii].	58.56	111	42	2	20	126	13	123	2e-38	137
rs:WP_044408690	phosphoribosyl-AMP cyclohydrolase [Thioalkalimicrobium microaerophilum].	50.38	131	63	1	2	130	10	140	2e-38	138
rs:WP_014104629	phosphoribosyl-AMP cyclohydrolase [Komagataeibacter medellinensis].	61.11	108	41	1	18	124	18	125	2e-38	137
rs:WP_031449929	phosphoribosyl-AMP cyclohydrolase [Desulfobacula sp. TS].	58.33	108	44	1	24	130	11	118	2e-38	137
tr:A0A094P947_9ACTN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	62.63	99	37	0	18	116	17	115	2e-38	137
rs:WP_018248754	hypothetical protein [Orenia marismortui].	58.18	110	44	1	16	123	4	113	2e-38	140
sp:HIS3_MAGSA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	63.64	99	36	0	16	114	11	109	3e-38	137
rs:WP_027363282	phosphoribosyl-AMP cyclohydrolase [Desulfotomaculum alcoholivorax].	54.55	121	54	1	11	130	1	121	3e-38	137
rs:WP_013432738	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Caldicellulosiruptor].	51.28	117	57	0	14	130	3	119	3e-38	139
rs:WP_004580145	phosphoribosyl-AMP cyclohydrolase [Marinobacter nanhaiticus].	54.78	115	47	2	6	119	8	118	3e-38	137
rs:WP_035593223	phosphoribosyl-AMP cyclohydrolase [Halomonas salina].	52.76	127	54	1	4	124	6	132	3e-38	137
rs:WP_022439652	phosphoribosyl-ATP diphosphatase [Clostridium sp. CAG:411].	58.93	112	44	1	5	116	210	319	3e-38	144
rs:WP_038297854	phosphoribosyl-AMP cyclohydrolase [actinobacterium acMicro-4].	62.63	99	37	0	18	116	11	109	3e-38	136
rs:WP_033318040	phosphoribosyl-AMP cyclohydrolase [Streptomyces yerevanensis].	59.26	108	42	1	18	123	21	128	3e-38	137
rs:WP_034451547	phosphoribosyl-AMP cyclohydrolase [Butyrivibrio sp. AE2032].	62.38	101	38	0	18	118	5	105	3e-38	136
rs:WP_043334240	phosphoribosyl-AMP cyclohydrolase [Cobetia marina].	59.48	116	46	1	7	121	17	132	3e-38	137
rs:WP_039884689	phosphoribosyl-AMP cyclohydrolase [Acidocella sp. MX-AZ02].	55.83	120	47	1	16	129	9	128	3e-38	137
sp:HIS3_THISH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.91	115	52	1	17	130	8	122	3e-38	137
tr:A9H153_GLUDA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	55.08	118	47	1	18	129	31	148	3e-38	137
rs:WP_016390656	phosphoribosyl-AMP cyclohydrolase [Cycloclasticus sp. PY97M].	57.41	108	46	0	18	125	27	134	3e-38	137
tr:A0A0D6MJX4_9PROT	SubName: Full=Phosphoribosyl AMP cyclohydrolase {ECO:0000313|EMBL:GAN53740.1};	65.62	96	33	0	18	113	10	105	3e-38	137
rs:WP_026440098	phosphoribosyl-AMP cyclohydrolase [Acidocella facilis].	55.83	120	47	1	16	129	9	128	3e-38	137
rs:WP_035528400	phosphoribosyl-AMP cyclohydrolase [Haliea salexigens].	61.86	97	36	1	18	113	5	101	3e-38	137
rs:WP_030307416	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-6131].	65.26	95	33	0	18	112	21	115	3e-38	137
rs:WP_012554752	phosphoribosyl-AMP cyclohydrolase [Gluconacetobacter diazotrophicus].	55.08	118	47	1	18	129	18	135	3e-38	137
rs:WP_019620191	hypothetical protein [Amphritea japonica].	61.39	101	39	0	17	117	26	126	3e-38	137
rs:WP_043210534	phosphoribosyl-AMP cyclohydrolase [Bordetella hinzii].	56.76	111	44	2	20	126	13	123	3e-38	137
rs:WP_009575275	phosphoribosyl-AMP cyclohydrolase [gamma proteobacterium IMCC3088].	60.58	104	40	1	16	118	7	110	4e-38	137
rs:WP_036904144	phosphoribosyl-AMP cyclohydrolase [Propionibacterium sp. KPL1844].	60.61	99	39	0	18	116	5	103	4e-38	136
rs:WP_011344013	phosphoribosyl-ATP pyrophosphatase [Carboxydothermus hydrogenoformans].	59.09	110	44	1	18	126	3	112	4e-38	139
rs:WP_014821918	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas stutzeri group].	55.26	114	50	1	18	130	7	120	4e-38	137
rs:WP_019605979	hypothetical protein [Teredinibacter turnerae].	54.24	118	52	1	2	117	9	126	4e-38	137
tr:H5SD72_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.39	114	51	1	18	130	8	121	4e-38	137
rs:WP_034785329	imidazole glycerol phosphate synthase [Eubacterium xylanophilum].	65.93	91	31	0	24	114	5	95	4e-38	139
rs:WP_038664194	phosphoribosyl-AMP cyclohydrolase [Pseudomonas stutzeri].	55.26	114	50	1	18	130	7	120	4e-38	137
tr:E3HQK4_ACHXA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	57.66	111	43	2	20	126	16	126	4e-38	137
tr:U7JGB0_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	60.61	99	39	0	18	116	57	155	4e-38	138
rs:WP_008893176	phosphoribosyl-AMP cyclohydrolase [Haloterrigena salina].	58.88	107	43	1	11	117	1	106	4e-38	136
tr:K5XW88_9PROT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	55.83	120	47	1	16	129	33	152	5e-38	137
rs:WP_033095156	phosphoribosyl-AMP cyclohydrolase [Colwellia psychrerythraea].	55.66	106	47	0	18	123	27	132	5e-38	137
rs:WP_044404515	phosphoribosyl-AMP cyclohydrolase, partial [Pseudomonas sp. FeS53a].	53.04	115	52	1	2	114	7	121	5e-38	136
rs:WP_030072991	phosphoribosyl-AMP cyclohydrolase [Halomonas alkaliantarctica].	56.14	114	50	0	18	131	35	148	5e-38	137
rs:WP_007153185	phosphoribosyl-AMP cyclohydrolase [Marinobacter algicola].	59.22	103	41	1	18	119	17	119	5e-38	137
rs:WP_021717502	phosphoribosyl-ATP diphosphatase [Phascolarctobacterium sp. CAG:207].	58.41	113	46	1	11	122	1	113	5e-38	139
rs:WP_011641157	phosphoribosyl-ATP pyrophosphatase [Syntrophomonas wolfei].	58.10	105	43	1	17	121	4	107	5e-38	139
rs:WP_043120586	phosphoribosyl-AMP cyclohydrolase, partial [Propionibacterium acidifaciens].	62.89	97	36	0	16	112	7	103	5e-38	135
rs:WP_041652068	phosphoribosyl-AMP cyclohydrolase [Achromobacter xylosoxidans].	57.66	111	43	2	20	126	13	123	5e-38	136
rs:WP_036210482	phosphoribosyl-AMP cyclohydrolase [Marinobacter sp. MCTG268].	59.22	103	41	1	18	119	17	119	6e-38	137
rs:WP_030364746	phosphoribosyl-AMP cyclohydrolase [Streptomyces roseoverticillatus].	65.26	95	33	0	18	112	19	113	6e-38	136
rs:WP_006606201	phosphoribosyl-AMP cyclohydrolase [Streptomyces auratus].	57.66	111	46	1	3	112	11	121	6e-38	136
rs:WP_045174947	imidazole glycerol phosphate synthase [Caldicellulosiruptor sp. Wai35.B1].	51.28	117	57	0	14	130	3	119	6e-38	138
rs:WP_043245642	phosphoribosyl-AMP cyclohydrolase [Pseudomonas alcaligenes].	50.00	128	62	1	2	127	7	134	6e-38	136
rs:WP_021220425	hypothetical protein [Pseudomonas alcaligenes].	50.00	128	62	1	2	127	7	134	6e-38	136
rs:WP_025131565	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. PH1b].	55.26	114	51	0	17	130	29	142	6e-38	137
rs:WP_025515012	phosphoribosyl-AMP cyclohydrolase [Bordetella trematum].	57.14	112	47	1	20	130	13	124	7e-38	136
rs:WP_026248536	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. LaPpAH-108].	65.26	95	33	0	18	112	21	115	7e-38	136
rs:WP_034336641	phosphoribosyl-AMP cyclohydrolase [Commensalibacter sp. MX01].	57.66	111	47	0	9	119	4	114	7e-38	136
rs:WP_003303025	phosphoribosyl-AMP cyclohydrolase [Pseudomonas stutzeri].	55.26	114	50	1	18	130	7	120	7e-38	136
rs:WP_046473515	phosphoribosyl-AMP cyclohydrolase [marine gamma proteobacterium ASP10-03a].	53.51	114	52	1	18	130	7	120	7e-38	136
rs:WP_038484253	phosphoribosyl-AMP cyclohydrolase [Halomonas campaniensis].	56.64	113	49	0	18	130	35	147	7e-38	137
rs:WP_027358911	phosphoribosyl-AMP cyclohydrolase [Desulforegula conservatrix].	57.39	115	47	2	18	130	5	119	8e-38	135
tr:U6ZWN3_9PSED	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	53.04	115	54	0	17	131	29	143	8e-38	136
rs:WP_029290086	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	59.41	101	41	0	17	117	25	125	8e-38	136
rs:WP_009834937	phosphoribosyl-AMP cyclohydrolase [Marinomonas sp. MED121].	61.22	98	38	0	16	113	22	119	8e-38	136
rs:WP_016966265	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	53.51	114	53	0	17	130	29	142	8e-38	136
rs:WP_041332559	phosphoribosyl-AMP cyclohydrolase [Marinobacter salarius].	59.22	103	41	1	18	119	17	119	8e-38	136
rs:WP_033303244	phosphoribosyl-AMP cyclohydrolase [Streptomyces atroolivaceus].	64.21	95	34	0	18	112	21	115	8e-38	135
tr:A0A0D6CAX9_9PSED	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:BAQ84054.1};	53.51	114	53	0	17	130	29	142	8e-38	136
rs:WP_030564475	phosphoribosyl-AMP cyclohydrolase [Streptomyces aureocirculatus].	56.25	112	48	1	2	112	1	112	8e-38	135
rs:WP_027349173	phosphoribosyl-AMP cyclohydrolase [Halotalea alkalilenta].	55.83	120	52	1	10	128	24	143	9e-38	136
rs:WP_017939404	phosphoribosyl-AMP cyclohydrolase [Pseudomonas thermotolerans].	55.26	114	50	1	18	130	8	121	9e-38	136
rs:WP_003620451	phosphoribosyl-AMP cyclohydrolase [Komagataeibacter hansenii].	63.92	97	35	0	18	114	18	114	9e-38	136
rs:WP_006063806	phosphoribosyl-AMP cyclohydrolase [Corynebacterium durum].	64.29	98	35	0	15	112	19	116	9e-38	135
rs:WP_029577761	phosphoribosyl-AMP cyclohydrolase [Bordetella hinzii].	55.86	111	45	2	20	126	13	123	9e-38	136
sp:HIS3_METBU	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	59.05	105	43	0	13	117	2	106	9e-38	135
rs:WP_037279178	phosphoribosyl-AMP cyclohydrolase [Ruminococcaceae bacterium AB4001].	60.40	101	40	0	18	118	5	105	9e-38	135
rs:WP_030808329	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-337].	65.26	95	33	0	18	112	21	115	1e-37	135
rs:WP_036160011	phosphoribosyl-AMP cyclohydrolase [Marinomonas ushuaiensis].	55.56	108	48	0	10	117	16	123	1e-37	136
tr:D4J841_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	65.66	99	34	0	16	114	208	306	1e-37	142
rs:WP_008408746	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	57.02	114	46	1	2	112	1	114	1e-37	135
rs:WP_030086797	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	64.21	95	34	0	18	112	22	116	1e-37	135
rs:WP_047290119	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	53.51	114	53	0	17	130	29	142	1e-37	136
rs:WP_013290381	phosphoribosyl-ATP pyrophosphatase [Caldicellulosiruptor obsidiansis].	53.04	115	54	0	14	128	3	117	1e-37	138
rs:WP_030262602	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL B-24484].	65.26	95	33	0	18	112	21	115	1e-37	135
rs:WP_014958959	phosphoribosyl-AMP cyclohydrolase [Desulfobacula toluolica].	53.72	121	53	2	11	130	4	122	1e-37	135
rs:WP_024056553	hypothetical protein [Streptococcus sp. DORA_10].	57.94	107	44	1	11	116	9	115	1e-37	135
rs:WP_013261763	phosphoribosyl-AMP cyclohydrolase [gamma proteobacterium HdN1].	55.65	124	49	1	1	118	1	124	1e-37	136
rs:WP_030211608	phosphoribosyl-AMP cyclohydrolase [Streptomyces griseoluteus].	64.21	95	34	0	18	112	13	107	1e-37	135
rs:WP_031094321	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-15].	64.21	95	34	0	18	112	21	115	1e-37	135
rs:WP_033094616	phosphoribosyl-AMP cyclohydrolase [Colwellia psychrerythraea].	57.41	108	46	0	18	125	27	134	1e-37	136
rs:WP_012973905	phosphoribosyl-AMP cyclohydrolase [Azospirillum lipoferum].	60.58	104	41	0	16	119	17	120	1e-37	136
rs:WP_041892897	phosphoribosyl-AMP cyclohydrolase [Candidatus Aerophobus profundus].	52.21	113	53	1	11	123	1	112	1e-37	135
rs:WP_015032902	phosphoribosyl-AMP cyclohydrolase [Streptomyces venezuelae].	62.24	98	37	0	15	112	10	107	1e-37	135
rs:WP_030583308	phosphoribosyl-AMP cyclohydrolase [Streptomyces globisporus].	64.21	95	34	0	18	112	22	116	1e-37	135
tr:D6AWQ0_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	57.02	114	46	1	2	112	4	117	1e-37	135
rs:WP_015508033	phosphoribosyl-AMP cyclohydrolase [Streptomyces albus].	57.02	114	46	1	2	112	1	114	1e-37	135
rs:WP_027280308	phosphoribosyl-AMP cyclohydrolase [Roseomonas gilardii].	57.02	114	49	0	18	131	8	121	1e-37	135
rs:WP_035158371	phosphoribosyl-AMP cyclohydrolase [Cobetia crustatorum].	61.68	107	41	0	7	113	17	123	1e-37	136
rs:WP_046907037	phosphoribosyl-AMP cyclohydrolase [Streptomyces showdoensis].	64.21	95	34	0	18	112	19	113	1e-37	135
rs:WP_030586651	phosphoribosyl-AMP cyclohydrolase [Streptomyces anulatus].	64.21	95	34	0	18	112	22	116	1e-37	135
rs:WP_018512040	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. ScaeMP-e10].	63.16	95	35	0	18	112	23	117	1e-37	135
rs:WP_014045372	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	55.65	115	48	1	1	112	1	115	1e-37	135
sp:HIS3_AZOSB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	54.70	117	51	2	16	130	9	125	1e-37	135
tr:K9SM96_9CYAN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	59.80	102	40	1	16	116	52	153	1e-37	136
rs:WP_026032998	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Roseomonas].	66.32	95	32	0	18	112	8	102	1e-37	135
tr:H5SBG1_9CHLR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	59.00	100	41	0	18	117	2	101	1e-37	134
rs:WP_034578788	phosphoribosyl-AMP cyclohydrolase [Carnimonas nigrificans].	55.26	114	51	0	18	131	28	141	1e-37	136
rs:WP_037699052	phosphoribosyl-AMP cyclohydrolase [Streptomyces atratus].	63.16	95	35	0	18	112	23	117	1e-37	135
rs:WP_028817561	phosphoribosyl-AMP cyclohydrolase [beta proteobacterium SCGC AAA027-K21].	57.55	106	44	1	20	124	15	120	1e-37	135
tr:G6EYT4_9PROT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	60.78	102	40	0	18	119	2	103	1e-37	135
rs:WP_023447081	phosphoribosyl-AMP cyclohydrolase [Pseudomonas chloritidismutans].	54.39	114	51	1	18	130	7	120	1e-37	135
rs:WP_033204624	phosphoribosyl-AMP cyclohydrolase [Streptomyces wedmorensis].	60.78	102	40	0	15	116	10	111	1e-37	135
rs:WP_035238437	phosphoribosyl-AMP cyclohydrolase [Desulfobacter vibrioformis].	57.27	110	40	2	11	119	4	107	1e-37	135
rs:WP_030057698	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	65.26	95	33	0	18	112	21	115	1e-37	135
rs:WP_027966869	phosphoribosyl-AMP cyclohydrolase [Halomonas halocynthiae].	60.00	105	42	0	20	124	28	132	1e-37	135
rs:WP_016913841	phosphoribosyl-AMP cyclohydrolase [Halomonas stevensii].	55.17	116	52	0	16	131	32	147	1e-37	136
tr:A0A0D6NHK5_9PROT	SubName: Full=Phosphoribosyl AMP cyclohydrolase {ECO:0000313|EMBL:GAN65120.1};	56.64	113	49	0	1	113	1	113	1e-37	135
rs:WP_030547280	phosphoribosyl-AMP cyclohydrolase [Streptomyces exfoliatus].	64.21	95	34	0	18	112	13	107	1e-37	135
rs:WP_009856604	phosphoribosyl-AMP cyclohydrolase [Rubrivivax benzoatilyticus].	52.54	118	52	1	17	130	6	123	1e-37	135
rs:WP_023415110	hypothetical protein [uncultured Thiohalocapsa sp. PB-PSB1].	61.39	101	39	0	16	116	26	126	2e-37	135
rs:WP_027403145	phosphoribosyl-AMP cyclohydrolase [Aphanizomenon flos-aquae].	61.76	102	38	1	17	117	10	111	2e-37	135
sp:HIS3_ACIAC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	48.48	132	63	2	3	130	5	135	2e-37	135
rs:WP_045992079	phosphoribosyl-AMP cyclohydrolase [Halomonas sp. S2151].	56.88	109	47	0	16	124	24	132	2e-37	135
rs:WP_010064530	phosphoribosyl-AMP cyclohydrolase [Streptomyces globisporus].	62.11	95	36	0	18	112	22	116	2e-37	135
rs:WP_045880444	phosphoribosyl-AMP cyclohydrolase [Pseudomonas chlororaphis].	53.91	115	53	0	17	131	29	143	2e-37	135
rs:WP_019146422	hypothetical protein [Aeromicrobium massiliense].	61.05	95	37	0	18	112	12	106	2e-37	134
rs:WP_027299363	phosphoribosyl-AMP cyclohydrolase [Rhodospirillales bacterium URHD0088].	62.24	98	37	0	16	113	3	100	2e-37	135
rs:WP_041100141	phosphoribosyl-AMP cyclohydrolase [Sulfuritalea hydrogenivorans].	56.25	112	48	1	20	130	15	126	2e-37	135
rs:WP_018555568	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. ATexAB-D23].	63.16	95	35	0	18	112	24	118	2e-37	135
rs:WP_006116475	phosphoribosyl-AMP cyclohydrolase [Acetobacter pomorum].	51.67	120	57	1	6	124	6	125	2e-37	135
sp:HIS3_STRGG	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	64.21	95	34	0	18	112	22	116	2e-37	135
rs:WP_022635598	phosphoribosyl-AMP cyclohydrolase [Chitinivibrio alkaliphilus].	60.40	101	40	0	18	118	11	111	2e-37	135
rs:WP_018957522	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. CNB091].	64.21	95	34	0	18	112	22	116	2e-37	135
rs:WP_013403160	phosphoribosyl-ATP pyrophosphatase [Caldicellulosiruptor hydrothermalis].	50.85	118	58	0	13	130	2	119	2e-37	137
rs:WP_032780383	phosphoribosyl-AMP cyclohydrolase [Streptomyces albus].	64.21	95	34	0	18	112	22	116	2e-37	135
rs:WP_030228132	phosphoribosyl-AMP cyclohydrolase [Streptomyces lavendulae].	64.21	95	34	0	18	112	17	111	2e-37	135
rs:WP_030064538	phosphoribosyl-AMP cyclohydrolase [Streptomyces natalensis].	58.04	112	46	1	2	112	1	112	2e-37	135
rs:WP_031089902	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL WC-3549].	64.21	95	34	0	18	112	21	115	2e-37	135
rs:WP_047176139	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. MNU77].	64.21	95	34	0	18	112	22	116	2e-37	135
rs:WP_030114333	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	64.21	95	34	0	18	112	22	116	2e-37	135
rs:WP_012360416	phosphoribosyl-AMP cyclohydrolase [Corynebacterium urealyticum].	64.21	95	34	0	18	112	14	108	2e-37	134
rs:WP_023004909	phosphoribosyl-AMP cyclohydrolase [Halomonas sp. PBN3].	53.60	125	56	1	6	130	16	138	2e-37	135
rs:WP_030771829	phosphoribosyl-AMP cyclohydrolase [Streptomyces griseus].	57.02	114	46	1	2	112	1	114	2e-37	135
tr:F3ZKA7_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	58.18	110	45	1	4	112	2	111	2e-37	134
rs:WP_031182908	phosphoribosyl-AMP cyclohydrolase [Streptomyces seoulensis].	63.16	95	35	0	18	112	21	115	2e-37	135
rs:WP_014141923	phosphoribosyl-AMP cyclohydrolase [Streptomyces cattleya].	64.21	95	34	0	18	112	17	111	2e-37	135
tr:A0A0D6NV35_9PROT	SubName: Full=Phosphoribosyl AMP cyclohydrolase {ECO:0000313|EMBL:GAN69450.1};	57.52	113	48	0	1	113	1	113	2e-37	135
rs:WP_043256367	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. Tu6071].	58.18	110	45	1	4	112	20	129	2e-37	135
rs:WP_032761562	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. CNS654].	64.21	95	34	0	18	112	22	116	2e-37	135
rs:WP_030850807	phosphoribosyl-AMP cyclohydrolase [Streptomyces griseus].	64.21	95	34	0	18	112	22	116	2e-37	135
rs:WP_030871546	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-2747].	64.21	95	34	0	18	112	17	111	2e-37	134
rs:WP_016468405	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	64.21	95	34	0	18	112	15	109	2e-37	134
rs:WP_031027394	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-5639].	64.21	95	34	0	18	112	15	109	2e-37	134
rs:WP_047122661	phosphoribosyl-AMP cyclohydrolase [Streptomyces leeuwenhoekii].	53.60	125	55	2	1	122	1	125	2e-37	135
rs:WP_040241164	phosphoribosyl-AMP cyclohydrolase [Chromohalobacter japonicus].	59.48	116	41	2	15	126	19	132	2e-37	135
rs:WP_045299117	phosphoribosyl-AMP cyclohydrolase [Saccharothrix sp. ST-888].	63.64	99	36	0	18	116	21	119	2e-37	134
rs:WP_024333675	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Desulfotignum].	52.89	121	50	2	11	130	4	118	2e-37	134
rs:WP_009024087	phosphoribosyl-AMP cyclohydrolase [gamma proteobacterium NOR5-3].	54.39	114	51	1	18	130	13	126	2e-37	135
rs:WP_029397382	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	58.18	110	45	1	4	112	2	111	2e-37	134
tr:S0G1D1_9DELT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.89	121	50	2	11	130	5	119	2e-37	134
rs:WP_042922679	phosphoribosyl-AMP cyclohydrolase [Pseudomonas chloritidismutans].	53.51	114	52	1	18	130	7	120	2e-37	135
rs:WP_041699879	phosphoribosyl-AMP cyclohydrolase [Pseudanabaena sp. PCC 7367].	59.80	102	40	1	16	116	7	108	2e-37	134
gpu:LN831790_5092	Phosphoribosyl-AMP cyclohydrolase [Streptomyces leeuwenhoekii]	53.60	125	55	2	1	122	4	128	2e-37	135
rs:WP_032784541	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. JS01].	63.16	95	35	0	18	112	22	116	2e-37	134
rs:WP_024022774	phosphoribosyl-AMP cyclohydrolase [Marinomonas profundimaris].	52.99	117	53	1	3	117	7	123	2e-37	135
rs:WP_019062280	phosphoribosyl-AMP cyclohydrolase [Streptomyces prunicolor].	53.66	123	54	2	2	121	1	123	2e-37	135
rs:WP_030564065	phosphoribosyl-AMP cyclohydrolase [Streptomyces cyaneofuscatus].	63.16	95	35	0	18	112	23	117	2e-37	134
rs:WP_020587810	phosphoribosyl-AMP cyclohydrolase [Desulfobacter curvatus].	54.78	115	45	2	11	124	4	112	2e-37	134
rs:WP_017238755	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. SS].	60.78	102	40	0	15	116	10	111	2e-37	134
rs:WP_021957420	phosphoribosyl-AMP cyclohydrolase [Eubacterium sp. CAG:115].	61.22	98	38	0	20	117	7	104	2e-37	134
rs:WP_028052857	phosphoribosyl-ATP pyrophosphatase [Carboxydothermus ferrireducens].	57.27	110	46	1	18	126	3	112	2e-37	137
rs:WP_044465859	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. MRSN12121].	53.91	115	53	0	17	131	29	143	2e-37	135
rs:WP_013796090	phosphoribosyl-AMP cyclohydrolase [Marinomonas posidonica].	53.10	113	51	1	7	117	11	123	2e-37	135
rs:WP_006621016	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Arthrospira].	62.75	102	37	1	17	117	10	111	2e-37	134
rs:WP_027249855	phosphoribosyl-AMP cyclohydrolase [Planktothrix agardhii].	61.39	101	38	1	18	117	11	111	2e-37	134
rs:WP_035409670	phosphoribosyl-AMP cyclohydrolase [Chromohalobacter israelensis].	58.62	116	42	1	4	113	6	121	2e-37	135
tr:A0A0D6JNG6_9EURY	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:CQR49145.1};	58.25	103	43	0	15	117	2	104	2e-37	134
rs:WP_009051648	phosphoribosyl-AMP cyclohydrolase [Pseudomonas chlororaphis].	47.41	135	58	1	2	123	1	135	3e-37	135
rs:WP_010505751	phosphoribosyl-AMP cyclohydrolase [gamma proteobacterium SCGC AAA007-O20].	50.43	115	56	1	17	130	6	120	3e-37	134
rs:WP_037934590	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. SPB78].	58.18	110	45	1	4	112	2	111	3e-37	134
rs:WP_041987975	phosphoribosyl-AMP cyclohydrolase [Pseudomonas chlororaphis].	47.41	135	58	1	2	123	1	135	3e-37	135
rs:WP_030805738	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces griseus group].	63.16	95	35	0	18	112	22	116	3e-37	134
rs:WP_030616927	phosphoribosyl-AMP cyclohydrolase [Streptomyces sclerotialus].	64.21	95	34	0	18	112	24	118	3e-37	134
rs:WP_021817561	phosphoribosyl-AMP cyclohydrolase [Halomonas sp. BJGMM-B45].	54.78	115	52	0	16	130	24	138	3e-37	135
rs:WP_005344876	phosphoribosyl-AMP cyclohydrolase [[Eubacterium] hallii].	56.60	106	44	1	9	114	3	106	3e-37	134
rs:WP_026795095	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Planktothrix].	61.39	101	38	1	18	117	11	111	3e-37	134
rs:WP_010130924	phosphoribosyl-AMP cyclohydrolase [Microbulbifer agarilyticus].	57.14	105	44	1	18	122	27	130	3e-37	135
tr:F3LDF2_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	56.88	109	47	0	17	125	7	115	3e-37	134
tr:A6VY24_MARMS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.87	113	49	1	7	117	11	123	3e-37	135
rs:WP_014585856	phosphoribosyl-AMP cyclohydrolase [Methanosaeta harundinacea].	63.44	93	34	0	25	117	7	99	3e-37	134
rs:WP_045664397	phosphoribosyl-AMP cyclohydrolase [Rhodospirillaceae bacterium BRH_c57].	57.14	105	45	0	16	120	13	117	3e-37	134
rs:WP_006123798	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	63.16	95	35	0	18	112	22	116	3e-37	134
rs:WP_045157967	phosphoribosyl-AMP cyclohydrolase [Pseudomonas stutzeri].	54.39	114	51	1	18	130	7	120	3e-37	134
rs:WP_026796820	phosphoribosyl-AMP cyclohydrolase [Planktothrix prolifica].	63.00	100	36	1	18	116	11	110	3e-37	134
rs:WP_037737217	phosphoribosyl-AMP cyclohydrolase [Streptomyces mirabilis].	56.25	112	48	1	2	112	4	115	3e-37	134
rs:WP_030719077	phosphoribosyl-AMP cyclohydrolase [Streptomyces griseus].	64.21	95	34	0	18	112	22	116	3e-37	134
rs:WP_021906641	phosphoribosyl-AMP cyclohydrolase [Eubacterium sp. CAG:146].	56.60	106	44	1	9	114	3	106	3e-37	134
rs:WP_041436163	imidazole glycerol phosphate synthase [Thermomicrobium roseum].	62.89	97	36	0	18	114	1	97	3e-37	137
rs:WP_003543220	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Desulfotomaculum].	59.46	111	44	1	11	120	1	111	3e-37	137
rs:WP_041948073	phosphoribosyl-ATP pyrophosphatase [Truepera radiovictrix].	59.05	105	43	0	17	121	5	109	3e-37	137
tr:D9UGQ4_STRS3	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	58.18	110	45	1	4	112	8	117	3e-37	134
rs:WP_030810021	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-2799].	63.16	95	35	0	18	112	21	115	3e-37	134
rs:WP_012941313	phosphoribosyl-AMP cyclohydrolase [Haloterrigena turkmenica].	57.94	107	44	1	11	117	1	106	3e-37	134
rs:WP_039177941	phosphoribosyl-AMP cyclohydrolase [Halomonas hydrothermalis].	55.17	116	52	0	16	131	32	147	3e-37	135
tr:B9KXC5_THERP	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	62.89	97	36	0	18	114	13	109	3e-37	137
rs:WP_005017577	phosphoribosyl-AMP cyclohydrolase [Bordetella holmesii].	57.55	106	44	1	20	124	13	118	3e-37	134
rs:WP_003805407	phosphoribosyl-AMP cyclohydrolase [Alcaligenes faecalis].	53.91	115	49	2	16	126	9	123	3e-37	134
rs:WP_028027568	phosphoribosyl-AMP cyclohydrolase [Enterorhabdus mucosicola].	59.43	106	42	1	13	117	1	106	3e-37	134
rs:WP_043550551	phosphoribosyl-AMP cyclohydrolase [Acetobacter malorum].	61.86	97	37	0	17	113	17	113	3e-37	134
rs:WP_008420989	phosphoribosyl-AMP cyclohydrolase [Natronococcus jeotgali].	57.69	104	44	0	14	117	2	105	3e-37	134
rs:WP_006618269	phosphoribosyl-AMP cyclohydrolase [Arthrospira platensis].	62.75	102	37	1	17	117	10	111	3e-37	134
rs:WP_004880362	hypothetical protein [Acinetobacter venetianus].	53.17	126	55	2	2	125	10	133	4e-37	134
sp:HIS3_PSEU5	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	54.39	114	51	1	18	130	7	120	4e-37	134
rs:WP_003297256	phosphoribosyl-AMP cyclohydrolase [Pseudomonas stutzeri].	54.39	114	51	1	18	130	7	120	4e-37	134
rs:WP_021912349	phosphoribosyl-AMP cyclohydrolase [Eubacterium sp. CAG:786].	61.22	98	38	0	20	117	7	104	4e-37	133
rs:WP_020552887	phosphoribosyl-AMP cyclohydrolase [Streptomyces scabrisporus].	63.16	95	35	0	18	112	22	116	4e-37	134
rs:WP_018518725	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	58.18	110	43	1	6	112	9	118	4e-37	134
rs:WP_027736705	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. CNT360].	63.16	95	35	0	18	112	15	109	4e-37	134
rs:WP_026136888	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. CBZ-4].	60.40	101	40	0	17	117	25	125	4e-37	134
rs:WP_028821061	phosphoribosyl-AMP cyclohydrolase [alpha proteobacterium SCGC AAA536-K22].	54.55	110	50	0	9	118	10	119	4e-37	134
rs:WP_007453154	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. W007].	63.16	95	35	0	18	112	22	116	4e-37	134
rs:WP_042621712	phosphoribosyl-AMP cyclohydrolase [Corynebacterium marinum].	64.58	96	34	0	18	113	18	113	4e-37	134
rs:WP_014595583	phosphoribosyl-AMP cyclohydrolase [Pseudomonas stutzeri].	54.39	114	51	1	18	130	7	120	4e-37	134
rs:WP_037448417	phosphoribosyl-AMP cyclohydrolase [Skermanella stibiiresistens].	56.64	113	49	0	18	130	14	126	4e-37	134
rs:WP_019358535	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. AA1529].	62.11	95	36	0	18	112	15	109	4e-37	134
rs:WP_030681867	phosphoribosyl-AMP cyclohydrolase [Streptomyces rimosus].	63.16	95	35	0	18	112	18	112	4e-37	134
rs:WP_013978201	phosphoribosyl-AMP cyclohydrolase [Clostridium sp. SY8519].	52.07	121	58	0	2	122	1	121	4e-37	134
rs:WP_031506671	phosphoribosyl-AMP cyclohydrolase [Streptomyces megasporus].	64.21	95	34	0	18	112	14	108	4e-37	134
tr:W2DNU5_9PSED	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	58.82	102	42	0	17	118	21	122	4e-37	134
rs:WP_030413638	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-1448].	64.21	95	34	0	18	112	21	115	4e-37	134
rs:WP_027590014	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonadaceae].	57.69	104	43	1	18	120	8	111	4e-37	134
rs:WP_027759603	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. CNT318].	62.11	95	36	0	18	112	15	109	4e-37	134
rs:WP_032856660	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. FH4].	58.82	102	42	0	17	118	25	126	4e-37	134
rs:WP_019384719	phosphoribosyl-AMP cyclohydrolase [Acinetobacter venetianus].	53.17	126	55	2	2	125	10	133	4e-37	134
rs:WP_029005134	phosphoribosyl-AMP cyclohydrolase [Azorhizobium doebereinerae].	60.58	104	39	1	19	120	26	129	4e-37	135
rs:WP_003984401	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	63.16	95	35	0	18	112	18	112	4e-37	134
rs:WP_039912618	phosphoribosyl-AMP cyclohydrolase [Cellvibrio mixtus].	52.17	115	54	1	17	130	7	121	4e-37	134
rs:WP_030281929	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	64.21	95	34	0	18	112	21	115	4e-37	134
rs:WP_027762495	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. CNS606].	55.75	113	49	1	1	112	1	113	4e-37	134
rs:WP_020306820	phosphoribosyl-AMP cyclohydrolase [Pseudomonas stutzeri].	54.39	114	51	1	18	130	7	120	5e-37	134
tr:D7CUB7_TRURR	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	62.50	96	36	0	18	113	15	110	5e-37	137
rs:WP_043651235	hypothetical protein, partial [Cellulosimicrobium cellulans].	58.18	110	45	1	4	112	9	118	5e-37	134
rs:WP_006185090	phosphoribosyl-AMP cyclohydrolase [Natrinema pallidum].	58.88	107	43	1	11	117	1	106	5e-37	134
rs:WP_040483758	phosphoribosyl-AMP cyclohydrolase [Lyngbya aestuarii].	60.75	107	41	1	17	122	10	116	5e-37	134
rs:WP_046899559	phosphoribosyl-AMP cyclohydrolase [Gluconobacter oxydans].	66.33	98	32	1	16	113	16	112	5e-37	134
tr:U7QMB9_9CYAN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	60.75	107	41	1	17	122	11	117	5e-37	134
rs:WP_046444637	hypothetical protein [Catabacter hongkongensis].	58.49	106	43	1	18	123	3	107	5e-37	136
rs:WP_022170358	phosphoribosyl-AMP cyclohydrolase [Eubacterium hallii CAG:12].	56.86	102	44	0	13	114	5	106	5e-37	133
rs:WP_043815435	phosphoribosyl-AMP cyclohydrolase [Rubrivivax gelatinosus].	52.54	118	52	1	17	130	6	123	5e-37	134
rs:WP_013430210	phosphoribosyl-ATP pyrophosphatase [Caldicellulosiruptor kronotskyensis].	49.57	117	59	0	14	130	3	119	5e-37	136
rs:WP_028353741	phosphoribosyl-AMP cyclohydrolase [Bordetella petrii].	57.66	111	43	2	20	126	13	123	5e-37	134
rs:WP_038557272	imidazole glycerol phosphate synthase [Synechococcus sp. KORDI-52].	65.98	97	32	1	18	113	12	108	5e-37	137
rs:WP_016972735	phosphoribosyl-AMP cyclohydrolase [Pseudomonas tolaasii].	56.14	114	49	1	18	130	8	121	5e-37	134
rs:WP_030020933	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	56.25	112	48	1	2	112	1	112	5e-37	134
rs:WP_014846703	phosphoribosyl-AMP cyclohydrolase [Propionibacterium propionicum].	56.70	97	42	0	18	114	11	107	5e-37	133
rs:WP_034095483	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens group].	55.26	114	50	1	18	130	8	121	5e-37	134
rs:WP_005878618	phosphoribosyl-AMP cyclohydrolase [Oxalobacter formigenes].	54.72	106	48	0	16	121	8	113	5e-37	134
rs:WP_018104497	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	57.27	110	44	1	6	112	9	118	5e-37	134
rs:WP_015607954	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	63.16	95	35	0	18	112	22	116	5e-37	134
rs:WP_013878741	phosphoribosyl-AMP cyclohydrolase [Halopiger xanaduensis].	56.73	104	45	0	14	117	3	106	5e-37	134
rs:WP_037870466	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. SPB74].	57.27	110	46	1	4	112	2	111	5e-37	133
rs:WP_043526038	phosphoribosyl-AMP cyclohydrolase [Halomonas xinjiangensis].	51.16	129	61	1	2	128	8	136	6e-37	134
tr:D6M2K9_STRSH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	57.27	110	46	1	4	112	8	117	6e-37	134
rs:WP_031069077	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL WC-3742].	63.16	95	35	0	18	112	21	115	6e-37	134
rs:WP_015907931	phosphoribosyl-ATP pyrophosphatase [Caldicellulosiruptor bescii].	49.15	118	60	0	13	130	2	119	6e-37	136
rs:WP_015323068	phosphoribosyl-AMP cyclohydrolase [Natronococcus occultus].	56.36	110	46	1	14	123	2	109	6e-37	133
rs:WP_028440220	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	57.80	109	45	1	5	112	7	115	6e-37	134
tr:W8X870_CASDE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.66	111	45	2	4	113	6	115	6e-37	134
rs:WP_003514582	phosphoribosyl-ATP pyrophosphatase [Ruminiclostridium thermocellum].	54.39	114	52	0	18	131	8	121	6e-37	136
rs:WP_015137598	phosphoribosyl-AMP cyclohydrolase [Nostoc sp. PCC 7524].	63.00	100	36	1	18	116	11	110	6e-37	133
tr:H3NX01_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	53.28	122	53	2	9	126	3	124	6e-37	134
rs:WP_030919455	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL B-24720].	63.16	95	35	0	18	112	23	117	6e-37	134
rs:WP_030245335	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-350].	64.21	95	34	0	18	112	21	115	6e-37	133
rs:WP_030972822	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-1824].	63.16	95	35	0	18	112	23	117	6e-37	134
rs:WP_008733534	phosphoribosyl-AMP cyclohydrolase [Alcanivorax pacificus].	60.38	106	41	1	18	123	23	127	6e-37	134
rs:WP_038444605	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	58.82	102	42	0	17	118	25	126	6e-37	134
rs:WP_042937063	phosphoribosyl-AMP cyclohydrolase [Pseudomonas gingeri].	58.65	104	43	0	17	120	4	107	6e-37	133
rs:WP_031048135	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL WC-3774].	53.23	124	55	2	1	121	1	124	6e-37	134
rs:WP_030361632	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	55.36	112	49	1	2	112	1	112	6e-37	134
rs:WP_031061945	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-5527].	63.16	95	35	0	18	112	35	129	6e-37	134
rs:WP_041128745	phosphoribosyl-AMP cyclohydrolase [Streptomyces vietnamensis].	62.63	99	37	0	18	116	19	117	6e-37	133
rs:WP_017738836	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. CBZ-4].	55.26	114	50	1	18	130	8	121	6e-37	134
rs:WP_007231977	phosphoribosyl-AMP cyclohydrolase [gamma proteobacterium HTCC2207].	52.63	114	53	1	18	130	7	120	6e-37	133
rs:WP_035949850	phosphoribosyl-AMP cyclohydrolase [Knoellia flava].	60.20	98	39	0	15	112	12	109	6e-37	133
rs:WP_012020268	phosphoribosyl-AMP cyclohydrolase [Pseudomonas mendocina].	51.72	116	56	0	10	125	20	135	6e-37	134
rs:WP_009455478	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Alcaligenes].	53.04	115	50	2	16	126	9	123	6e-37	134
rs:WP_031128445	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL WC-3719].	64.21	95	34	0	18	112	13	107	7e-37	133
rs:WP_025367516	phosphoribosyl-AMP cyclohydrolase [Thioalkalivibrio thiocyanoxidans].	57.76	116	49	0	16	131	21	136	7e-37	134
rs:WP_006136096	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	63.16	95	35	0	18	112	35	129	7e-37	134
tr:C8Z2I5_CHRSL	SubName: Full=Phosphoribosyl AMP-cyclohydrolase {ECO:0000313|EMBL:CAX46381.1}; Flags: Fragment;	65.26	95	33	0	19	113	27	121	7e-37	134
rs:WP_014434658	phosphoribosyl-AMP cyclohydrolase [Caldilinea aerophila].	60.42	96	38	0	18	113	10	105	7e-37	133
sp:HIS3_PROA2	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	56.86	102	44	0	17	118	14	115	7e-37	134
sp:HIS3_SYNAS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	65.56	90	31	0	24	113	11	100	7e-37	133
rs:WP_046928537	phosphoribosyl-AMP cyclohydrolase [Streptomyces lydicus].	61.22	98	38	0	15	112	14	111	7e-37	133
tr:I5AZM3_9DELT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	53.91	115	46	2	11	124	29	137	7e-37	134
rs:WP_040438207	phosphoribosyl-AMP cyclohydrolase, partial [Aestuariimicrobium kwangyangense].	64.21	95	34	0	18	112	18	112	7e-37	133
rs:WP_040802216	phosphoribosyl-AMP cyclohydrolase [gamma proteobacterium HIMB55].	56.88	109	46	1	19	126	4	112	7e-37	133
rs:WP_034651033	phosphoribosyl-AMP cyclohydrolase, partial [Cellulosimicrobium sp. MM].	60.00	105	41	1	9	112	3	107	7e-37	133
rs:WP_030589370	phosphoribosyl-AMP cyclohydrolase [Streptomyces rimosus].	62.11	95	36	0	18	112	18	112	7e-37	133
rs:WP_037623349	phosphoribosyl-AMP cyclohydrolase [Streptomyces aureus].	55.36	112	49	1	2	112	1	112	7e-37	134
tr:E6MGJ0_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	56.25	112	44	1	2	113	4	110	7e-37	136
rs:WP_030088813	phosphoribosyl-AMP cyclohydrolase [Streptomyces decoyicus].	63.16	95	35	0	18	112	22	116	7e-37	133
rs:WP_004870431	phosphoribosyl-AMP cyclohydrolase [Acidithiobacillus caldus].	55.24	105	47	0	16	120	11	115	8e-37	136
rs:WP_043685358	phosphoribosyl-AMP cyclohydrolase, partial [Castellaniella defragrans].	61.62	99	37	1	16	113	2	100	8e-37	133
rs:WP_038288346	imidazole glycerol phosphate synthase [[Clostridium] straminisolvens].	55.26	114	51	0	18	131	8	121	8e-37	136
sp:HIS3_CHRSD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	65.26	95	33	0	19	113	27	121	8e-37	134
rs:WP_025806933	phosphoribosyl-AMP cyclohydrolase [Pseudomonas chlororaphis].	56.60	106	46	0	18	123	30	135	8e-37	134
rs:WP_043263911	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. CT34].	63.16	95	35	0	18	112	30	124	8e-37	134
rs:WP_003280975	phosphoribosyl-AMP cyclohydrolase [Pseudomonas stutzeri].	53.51	114	52	1	18	130	7	120	8e-37	133
rs:WP_006092703	phosphoribosyl-AMP cyclohydrolase [Natronorubrum tibetense].	53.72	121	53	2	14	131	3	123	8e-37	133
tr:I7AZY7_PSEPT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	55.26	114	50	1	18	130	8	121	8e-37	133
rs:WP_028468148	phosphoribosyl-AMP cyclohydrolase [Neptunomonas japonica].	57.69	104	43	1	17	119	8	111	8e-37	133
rs:WP_042485724	phosphoribosyl-AMP cyclohydrolase [Alcaligenes faecalis].	53.04	115	50	2	16	126	9	123	8e-37	133
rs:WP_020083881	phosphoribosyl-AMP cyclohydrolase [gamma proteobacterium SCGC AAA160-D02].	50.43	115	56	1	18	131	8	122	8e-37	133
rs:WP_030988659	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-1813].	63.16	95	35	0	18	112	22	116	8e-37	133
rs:WP_031316413	hypothetical protein, partial [Bacillus sp. EGD-AK10].	60.00	105	41	1	9	112	3	107	8e-37	133
tr:U2A7B7_9BACI	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:ERI40752.1}; Flags: Fragment;	60.00	105	41	1	9	112	14	118	8e-37	134
rs:WP_022873291	phosphoribosyl-AMP cyclohydrolase [Nesterenkonia alba].	58.76	97	40	0	16	112	5	101	8e-37	132
rs:WP_024510634	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. ARR65].	58.25	103	43	0	19	121	18	120	8e-37	134
rs:WP_030642109	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	64.21	95	34	0	18	112	21	115	8e-37	133
rs:WP_014746878	phosphoribosyl-AMP cyclohydrolase [Tistrella mobilis].	57.02	114	49	0	11	124	21	134	8e-37	134
rs:WP_015637550	phosphoribosyl-AMP cyclohydrolase [Pseudomonas protegens].	48.09	131	66	1	2	130	12	142	8e-37	134
rs:WP_023589171	phosphoribosyl-AMP cyclohydrolase [Streptomyces thermolilacinus].	63.16	95	35	0	18	112	13	107	9e-37	133
sp:HIS3_BORA1	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	54.95	111	46	2	20	126	13	123	9e-37	133
rs:WP_022363956	phosphoribosyl-AMP cyclohydrolase [Eggerthella sp. CAG:298].	63.54	96	35	0	18	113	6	101	9e-37	132
rs:WP_024543786	phosphoribosyl-AMP cyclohydrolase [actinobacterium SCGC AAA044-D11].	59.38	96	39	0	19	114	11	106	9e-37	132
tr:S6GSQ4_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	58.42	101	41	1	20	119	16	116	9e-37	133
rs:WP_013278409	phosphoribosyl-ATP pyrophosphatase [Acetohalobium arabaticum].	62.50	96	36	0	18	113	7	102	9e-37	136
rs:WP_041285416	phosphoribosyl-AMP cyclohydrolase [Desulfotomaculum gibsoniae].	55.26	114	50	1	18	130	6	119	9e-37	133
rs:WP_022523467	phosphoribosyl-AMP cyclohydrolase [Halomonas sp. A3H3].	55.17	116	52	0	16	131	33	148	9e-37	134
rs:WP_022378508	phosphoribosyl-AMP cyclohydrolase [Cryptobacterium sp. CAG:338].	62.24	98	37	0	16	113	4	101	9e-37	132
rs:WP_007927616	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. GM17].	46.67	135	59	1	2	123	1	135	9e-37	134
rs:WP_034605190	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. NBRC 100985].	53.17	126	55	2	2	125	10	133	9e-37	133
rs:WP_018536745	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. MspMP-M5].	56.64	113	48	1	1	112	1	113	9e-37	133
rs:WP_006630561	phosphoribosyl-AMP cyclohydrolase [Halorubrum tebenquichense].	58.10	105	43	1	13	117	6	109	9e-37	133
rs:WP_015257718	phosphoribosyl-AMP cyclohydrolase [Thioalkalivibrio nitratireducens].	58.77	114	47	0	18	131	23	136	9e-37	134
rs:WP_018486589	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	62.11	95	36	0	18	112	22	116	9e-37	133
rs:WP_020222311	phosphoribosyl-AMP cyclohydrolase [Halarchaeum acidiphilum].	60.00	100	40	0	18	117	12	111	9e-37	133
rs:WP_027959427	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Halomonas].	55.17	116	52	0	16	131	33	148	9e-37	134
rs:WP_037001773	phosphoribosyl-AMP cyclohydrolase [Pseudomonas pseudoalcaligenes].	52.59	116	55	0	10	125	20	135	1e-36	133
rs:WP_040186787	phosphoribosyl-AMP cyclohydrolase [Halomonas salina].	55.75	113	50	0	18	130	26	138	1e-36	134
rs:WP_043223190	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-5193].	63.16	95	35	0	18	112	19	113	1e-36	133
rs:WP_043893230	phosphoribosyl-AMP cyclohydrolase [Osedax symbiont Rs2].	58.42	101	41	1	20	119	11	111	1e-36	133
rs:WP_030155922	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-244].	63.16	95	35	0	18	112	17	111	1e-36	133
rs:WP_023530574	phosphoribosyl-AMP cyclohydrolase [Streptomycetaceae bacterium MP113-05].	54.87	113	50	1	1	112	1	113	1e-36	133
rs:WP_014672124	phosphoribosyl-AMP cyclohydrolase [Streptomyces hygroscopicus].	64.21	95	34	0	18	112	21	115	1e-36	133
rs:WP_009206612	phosphoribosyl-AMP cyclohydrolase [Sulfuricella denitrificans].	49.59	123	61	1	9	130	2	124	1e-36	133
rs:WP_040016168	phosphoribosyl-AMP cyclohydrolase [Desulfobacter postgatei].	53.91	115	46	2	11	124	4	112	1e-36	133
rs:WP_030909276	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-5126].	63.16	95	35	0	18	112	16	110	1e-36	133
rs:WP_044270698	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	55.26	114	50	1	18	130	8	121	1e-36	133
rs:WP_046279684	phosphoribosyl-AMP cyclohydrolase [Limnoraphis robusta].	63.37	101	36	1	17	116	10	110	1e-36	133
tr:I3I6C8_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	51.75	114	54	1	18	130	1	114	1e-36	132
tr:R4KFB4_9FIRM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	55.26	114	50	1	18	130	11	124	1e-36	133
rs:WP_029018586	phosphoribosyl-AMP cyclohydrolase [actinobacterium SCGC AAA028-I14].	54.05	111	51	0	9	119	2	112	1e-36	132
rs:WP_036233405	phosphoribosyl-AMP cyclohydrolase [Massilia sp. JS1662].	50.00	116	57	1	16	130	9	124	1e-36	133
tr:A0A076HK58_9SYNE	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	65.98	97	32	1	18	113	31	127	1e-36	136
rs:WP_009041411	phosphoribosyl-AMP cyclohydrolase [Pseudomonas chlororaphis].	46.67	135	59	1	2	123	1	135	1e-36	133
rs:WP_010502481	phosphoribosyl-AMP cyclohydrolase [Gluconobacter frateurii].	62.86	105	38	1	9	113	9	112	1e-36	133
rs:WP_009625679	phosphoribosyl-AMP cyclohydrolase [Pseudanabaena biceps].	63.37	101	36	1	17	116	8	108	1e-36	132
tr:G7GGR6_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	53.17	126	55	2	2	125	12	135	1e-36	133
rs:WP_025861591	phosphoribosyl-AMP cyclohydrolase [Acetobacter papayae].	58.10	105	44	0	9	113	9	113	1e-36	133
rs:WP_015278594	phosphoribosyl-AMP cyclohydrolase [Pseudomonas stutzeri].	52.63	114	53	1	18	130	7	120	1e-36	133
rs:WP_030783971	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-920].	63.16	95	35	0	18	112	23	117	1e-36	133
rs:WP_019814530	phosphoribosyl-AMP cyclohydrolase [Osedax symbiont Rs1].	51.30	115	55	1	17	130	8	122	1e-36	133
rs:WP_019067712	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. R1-NS-10].	55.36	112	49	1	2	112	1	112	1e-36	133
rs:WP_024492685	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. AW19M42].	62.11	95	36	0	18	112	24	118	1e-36	133
rs:WP_035579300	phosphoribosyl-AMP cyclohydrolase [Halomonas sp. TG39a].	54.78	115	52	0	16	130	33	147	1e-36	134
rs:WP_021779845	phosphoribosyl-AMP cyclohydrolase [Halarchaeum acidiphilum].	60.00	100	40	0	18	117	3	102	1e-36	132
rs:WP_031286195	phosphoribosyl-AMP cyclohydrolase [Pseudomonas chlororaphis].	46.67	135	59	1	2	123	1	135	1e-36	133
rs:WP_040357918	phosphoribosyl-AMP cyclohydrolase, partial [Corynebacterium ciconiae].	62.11	95	36	0	18	112	19	113	1e-36	132
rs:WP_040640295	imidazole glycerol phosphate synthase [Pseudoramibacter alactolyticus].	58.33	108	40	1	6	113	2	104	1e-36	135
gpu:CP011497_5275	phosphoribosyl-AMP cyclohydrolase [Streptomyces incarnatus]	63.16	95	35	0	18	112	19	113	1e-36	133
tr:D6KAP1_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	52.31	130	61	1	2	130	1	130	1e-36	134
rs:WP_030734184	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-2890].	58.88	107	41	1	9	112	4	110	1e-36	132
rs:WP_030256386	phosphoribosyl-AMP cyclohydrolase [Streptomyces violens].	63.16	95	35	0	18	112	23	117	1e-36	133
rs:WP_032893977	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. Eur1 9.41].	55.26	114	50	1	18	130	8	121	1e-36	133
rs:WP_036176244	phosphoribosyl-AMP cyclohydrolase [Massilia sp. 9096].	50.88	114	55	1	18	130	10	123	1e-36	133
rs:WP_015326681	phosphoribosyl-ATP pyrophosphohydrolase [Halobacteroides halobius].	58.00	100	42	0	18	117	6	105	1e-36	135
rs:WP_040896923	phosphoribosyl-AMP cyclohydrolase, partial [Streptomyces griseoaurantiacus].	63.16	95	35	0	18	112	22	116	1e-36	132
rs:WP_035517939	phosphoribosyl-AMP cyclohydrolase [Pseudohaliea rubra].	55.17	116	51	1	16	130	7	122	1e-36	133
rs:WP_037774950	phosphoribosyl-AMP cyclohydrolase [Streptomyces pristinaespiralis].	56.25	112	48	1	2	112	1	112	1e-36	132
tr:B0AB97_9FIRM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.99	117	54	1	1	116	1	117	1e-36	132
rs:WP_031132061	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	59.43	106	41	1	18	121	19	124	1e-36	133
rs:WP_019621306	phosphoribosyl-AMP cyclohydrolase [Amphritea japonica].	57.28	103	43	1	18	119	9	111	1e-36	133
rs:WP_040507753	phosphoribosyl-AMP cyclohydrolase [Gluconobacter morbifer].	64.29	98	34	1	16	113	16	112	1e-36	133
rs:WP_006377512	phosphoribosyl-AMP cyclohydrolase [Streptomyces turgidiscabies].	62.11	95	36	0	18	112	25	119	1e-36	133
rs:WP_019093405	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens group].	52.63	114	54	0	17	130	29	142	1e-36	133
sp:HIS32_PSEF5	RecName: Full=Phosphoribosyl-AMP cyclohydrolase 2 {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH 2 {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.63	114	54	0	17	130	29	142	1e-36	133
rs:WP_010324390	phosphoribosyl-AMP cyclohydrolase [Marinobacterium stanieri].	55.45	110	48	1	18	126	9	118	1e-36	133
rs:WP_022993077	phosphoribosyl-AMP cyclohydrolase [Marinobacter sp. C1S70].	57.28	103	43	1	18	119	17	119	1e-36	133
rs:WP_044400239	phosphoribosyl-AMP cyclohydrolase [Acidovorax temperans].	49.58	119	56	1	16	130	5	123	1e-36	132
rs:WP_030291978	phosphoribosyl-AMP cyclohydrolase [Streptomyces katrae].	63.16	95	35	0	18	112	17	111	1e-36	132
rs:WP_038574566	phosphoribosyl-AMP cyclohydrolase [Pseudomonas chlororaphis].	46.67	135	59	1	2	123	1	135	1e-36	133
rs:WP_044288079	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	59.41	101	41	0	17	117	25	125	1e-36	133
rs:WP_023012466	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. COS3].	52.38	126	56	2	2	125	10	133	1e-36	133
rs:WP_005664403	phosphoribosyl-AMP cyclohydrolase [Massilia timonae].	49.14	116	58	1	16	130	9	124	1e-36	133
rs:WP_019498249	hypothetical protein [Pseudanabaena sp. PCC 6802].	61.17	103	39	1	18	119	11	113	1e-36	132
rs:WP_036569208	phosphoribosyl-AMP cyclohydrolase [Nocardioides sp. URHA0032].	62.11	95	36	0	18	112	15	109	1e-36	132
tr:D6X909_STRPR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	56.25	112	48	1	2	112	4	115	1e-36	132
rs:WP_006007791	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio piger].	58.33	108	44	1	24	130	15	122	1e-36	132
rs:WP_007416997	phosphoribosyl-AMP cyclohydrolase [Pedosphaera parvula].	53.85	104	48	0	18	121	7	110	1e-36	132
rs:WP_010132027	phosphoribosyl-AMP cyclohydrolase [Microbulbifer agarilyticus].	52.85	123	56	2	9	130	2	123	1e-36	133
rs:WP_004845096	imidazole glycerol phosphate synthase [[Ruminococcus] torques].	60.19	108	41	1	9	116	222	327	1e-36	140
rs:WP_039858496	phosphoribosyl-AMP cyclohydrolase [Halomonas titanicae].	57.14	112	48	0	19	130	36	147	1e-36	133
rs:WP_014427248	phosphoribosyl-AMP cyclohydrolase [Rubrivivax gelatinosus].	52.54	118	52	1	17	130	6	123	1e-36	132
rs:WP_031002571	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-5727].	55.17	116	49	1	4	116	2	117	2e-36	132
rs:WP_005555012	phosphoribosyl-AMP cyclohydrolase [Natronococcus amylolyticus].	56.73	104	45	0	14	117	2	105	2e-36	132
tr:G9YVS5_9FIRM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	59.00	100	41	0	13	112	2	101	2e-36	132
rs:WP_030883440	phosphoribosyl-AMP cyclohydrolase [Streptomyces varsoviensis].	62.11	95	36	0	18	112	21	115	2e-36	132
rs:WP_040393196	phosphoribosyl-AMP cyclohydrolase [Cellvibrio sp. BR].	51.30	115	55	1	17	130	7	121	2e-36	132
sp:HIS3_RHOFT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.99	117	51	1	18	130	7	123	2e-36	132
rs:WP_009256677	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Clostridiales].	59.00	100	41	0	13	112	6	105	2e-36	132
rs:WP_013593481	phosphoribosyl-AMP cyclohydrolase [Acidovorax avenae].	51.28	117	53	1	18	130	7	123	2e-36	132
rs:WP_030637949	phosphoribosyl-AMP cyclohydrolase [Streptomyces flavovirens].	56.88	109	46	1	5	112	7	115	2e-36	132
rs:WP_026788321	phosphoribosyl-AMP cyclohydrolase [Planktothrix rubescens].	60.40	101	39	1	18	117	11	111	2e-36	132
sp:HIS3_PROVI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.39	127	61	2	5	130	3	128	2e-36	133
rs:WP_033820233	phosphoribosyl-AMP cyclohydrolase [Kitasatospora sp. MBT63].	62.11	95	36	0	18	112	21	115	2e-36	132
rs:WP_014156796	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	56.88	109	46	1	5	112	7	115	2e-36	132
rs:WP_008957955	phosphoribosyl-AMP cyclohydrolase [Halomonas sp. HAL1].	57.80	109	46	0	16	124	33	141	2e-36	133
rs:WP_041675036	phosphoribosyl-AMP cyclohydrolase [Ramlibacter tataouinensis].	51.69	118	53	1	17	130	6	123	2e-36	132
rs:WP_022306250	phosphoribosyl-ATP diphosphatase [Roseburia sp. CAG:380].	59.43	106	41	1	9	114	144	247	2e-36	138
rs:WP_012996596	phosphoribosyl-AMP cyclohydrolase [Natrialba magadii].	58.00	100	42	0	18	117	9	108	2e-36	133
rs:WP_028629818	phosphoribosyl-AMP cyclohydrolase [Pseudomonas resinovorans].	54.39	114	51	1	18	130	8	121	2e-36	132
tr:R5QDH8_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	60.19	108	41	1	9	116	222	327	2e-36	139
rs:WP_041827817	phosphoribosyl-AMP cyclohydrolase [Acidovorax citrulli].	51.28	117	53	1	18	130	7	123	2e-36	132
rs:WP_027254394	phosphoribosyl-AMP cyclohydrolase [Planktothrix agardhii].	58.82	102	41	1	17	117	10	111	2e-36	132
rs:WP_028658783	phosphoribosyl-AMP cyclohydrolase [Nocardioides insulae].	58.10	105	43	1	9	112	3	107	2e-36	132
rs:WP_020679644	hypothetical protein [Marinobacterium rhizophilum].	57.28	103	43	1	18	119	9	111	2e-36	132
rs:WP_012537569	phosphoribosyl-AMP cyclohydrolase [Acidithiobacillus ferrooxidans].	60.20	98	39	0	16	113	13	110	2e-36	135
rs:WP_044939791	phosphoribosyl-AMP cyclohydrolase [Flavonifractor plautii].	59.00	100	41	0	13	112	6	105	2e-36	132
rs:WP_045212898	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. 21].	56.14	114	49	1	18	130	8	121	2e-36	132
tr:L9UDU2_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	56.64	113	49	0	19	131	58	170	2e-36	134
rs:WP_030380283	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	63.16	95	35	0	18	112	23	117	2e-36	132
rs:WP_007141477	phosphoribosyl-AMP cyclohydrolase [Halobiforma lacisalsi].	57.69	104	44	0	14	117	3	106	2e-36	132
rs:WP_039905987	phosphoribosyl-AMP cyclohydrolase [Intestinibacter bartlettii].	55.45	110	48	1	8	116	6	115	2e-36	132
rs:WP_035488773	phosphoribosyl-AMP cyclohydrolase [Gammaproteobacteria bacterium MOLA455].	50.88	114	55	1	18	130	7	120	2e-36	132
tr:G6XGW4_9PROT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	64.29	98	34	1	16	113	24	120	2e-36	133
rs:WP_034105968	phosphoribosyl-AMP cyclohydrolase [Desulfotomaculum sp. BICA1-6].	57.27	110	46	1	11	119	1	110	2e-36	132
rs:WP_007282239	phosphoribosyl-AMP cyclohydrolase [Gluconobacter thailandicus].	63.11	103	37	1	11	113	11	112	2e-36	132
rs:WP_014030243	phosphoribosyl-AMP cyclohydrolase [Acidithiobacillus ferrivorans].	59.18	98	40	0	16	113	13	110	2e-36	135
rs:WP_004811368	phosphoribosyl-AMP cyclohydrolase [Propionibacterium avidum].	60.00	95	38	0	18	112	21	115	2e-36	132
sp:HIS3_PSEP1	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	55.26	114	50	1	18	130	8	121	2e-36	132
rs:WP_018638171	hypothetical protein [Frankia sp. BMG5.12].	61.05	95	37	0	18	112	16	110	2e-36	132
rs:WP_044387669	phosphoribosyl-AMP cyclohydrolase [Streptomyces cyaneogriseus].	52.85	123	55	2	1	120	1	123	2e-36	132
rs:WP_013779920	phosphoribosyl-ATP pyrophosphatase [Mahella australiensis].	52.54	118	56	0	11	128	1	118	2e-36	134
tr:M2ZZP7_STRMB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	62.11	95	36	0	18	112	38	132	2e-36	132
rs:WP_045857889	phosphoribosyl-AMP cyclohydrolase [Alteromonadaceae bacterium Bs12].	50.88	114	55	1	18	130	11	124	2e-36	132
rs:WP_021491455	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	59.41	101	41	0	17	117	25	125	2e-36	132
rs:WP_037043899	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. BAY1663].	54.39	114	51	1	18	130	7	120	2e-36	132
rs:WP_015079348	phosphoribosyl-AMP cyclohydrolase [Anabaena sp. 90].	61.39	101	38	1	17	116	4	104	2e-36	132
rs:WP_026432670	phosphoribosyl-AMP cyclohydrolase [Acidovorax oryzae].	51.28	117	53	1	18	130	7	123	2e-36	132
rs:WP_021783739	phosphoribosyl-AMP cyclohydrolase [Pseudomonas putida].	55.26	114	50	1	18	130	8	121	2e-36	132
rs:WP_029017725	phosphoribosyl-AMP cyclohydrolase [actinobacterium SCGC AAA027-D23].	58.76	97	40	0	16	112	7	103	2e-36	132
rs:WP_035190662	phosphoribosyl-AMP cyclohydrolase [Acidithiobacillus ferrivorans].	59.18	98	40	0	16	113	13	110	2e-36	135
rs:WP_042162200	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NBRC 110027].	62.11	95	36	0	18	112	22	116	2e-36	132
rs:WP_032628060	phosphoribosyl-AMP cyclohydrolase [Pseudomonas syringae].	53.51	114	52	1	18	130	8	121	2e-36	132
rs:WP_020229050	phosphoribosyl-AMP cyclohydrolase [Acidovorax sp. MR-S7].	51.28	117	53	1	18	130	13	129	2e-36	132
rs:WP_032884499	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. RIT357].	58.42	101	42	0	17	117	25	125	2e-36	132
rs:WP_014059958	phosphoribosyl-AMP cyclohydrolase [Streptomyces violaceusniger].	62.11	95	36	0	18	112	18	112	2e-36	132
sp:HIS3_DESAH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	58.56	111	44	2	18	126	4	114	2e-36	132
rs:WP_003187884	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	54.39	114	51	1	18	130	8	121	2e-36	132
rs:WP_008013624	phosphoribosyl-AMP cyclohydrolase [Haloterrigena limicola].	56.73	104	45	0	14	117	3	106	2e-36	132
rs:WP_006648536	phosphoribosyl-AMP cyclohydrolase [Haloterrigena thermotolerans].	57.43	101	43	0	17	117	6	106	2e-36	132
tr:A0A0A8P958_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	62.11	95	36	0	18	112	34	128	2e-36	132
rs:WP_030831770	phosphoribosyl-AMP cyclohydrolase [Streptomyces hygroscopicus].	63.16	95	35	0	18	112	18	112	2e-36	132
rs:WP_014422688	phosphoribosyl-AMP cyclohydrolase [Marinobacter hydrocarbonoclasticus].	57.28	103	43	1	18	119	17	119	2e-36	132
rs:WP_041990779	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. AcH 505].	62.11	95	36	0	18	112	22	116	2e-36	132
rs:WP_027356401	phosphoribosyl-ATP pyrophosphatase [Desulfotomaculum thermocisternum].	59.22	103	42	0	11	113	1	103	2e-36	136
rs:WP_014180505	phosphoribosyl-AMP cyclohydrolase [Streptomyces bingchenggensis].	62.11	95	36	0	18	112	18	112	2e-36	132
rs:WP_037978866	hypothetical protein, partial [Streptomyces sp. TAA040].	62.11	95	36	0	18	112	14	108	2e-36	132
rs:WP_024757910	phosphoribosyl-AMP cyclohydrolase [Streptomyces exfoliatus].	62.11	95	36	0	18	112	13	107	2e-36	132
rs:WP_021249728	phosphoribosyl-AMP cyclohydrolase [Thauera terpenica].	58.59	99	40	1	16	113	9	107	2e-36	132
rs:WP_027608203	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. LAMO17WK12:I2].	59.62	104	41	1	17	120	25	127	2e-36	132
rs:WP_026169751	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. FxanaC1].	62.11	95	36	0	18	112	22	116	2e-36	132
rs:WP_013517782	phosphoribosyl-AMP cyclohydrolase [Alicycliphilus denitrificans].	50.43	117	54	1	18	130	7	123	2e-36	132
rs:WP_034690988	phosphoribosyl-AMP cyclohydrolase [Acidovorax sp. MR-S7].	51.28	117	53	1	18	130	7	123	2e-36	132
rs:WP_031068866	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-118].	62.11	95	36	0	18	112	13	107	2e-36	132
sp:HIS3_PSEPG	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	55.26	114	50	1	18	130	8	121	2e-36	132
tr:A0A0A8PJC8_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	62.11	95	36	0	18	112	34	128	2e-36	132
tr:F3NRB0_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	63.16	95	35	0	18	112	38	132	2e-36	133
rs:WP_026300347	phosphoribosyl-AMP cyclohydrolase [Halomonas lutea].	57.80	109	44	1	18	126	23	129	2e-36	132
rs:WP_018995664	phosphoribosyl-AMP cyclohydrolase [Hirschia maritima].	61.00	100	39	0	19	118	28	127	2e-36	132
rs:WP_008170988	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Marinobacter].	57.28	103	43	1	18	119	17	119	2e-36	132
rs:WP_010666888	phosphoribosyl-AMP cyclohydrolase [Acetobacter aceti].	59.62	104	42	0	10	113	15	118	2e-36	132
tr:H0IXG3_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.87	113	50	1	18	129	25	137	2e-36	132
rs:WP_017476791	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. PAMC 26793].	54.24	118	52	1	2	117	8	125	2e-36	132
sp:HIS3_DESAA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	59.26	108	37	2	11	117	4	105	2e-36	132
rs:WP_037863679	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-340].	59.05	105	41	1	18	120	21	125	2e-36	132
rs:WP_039202291	phosphoribosyl-AMP cyclohydrolase [Aphanizomenon flos-aquae].	62.24	98	36	1	17	113	4	101	2e-36	131
rs:WP_006349837	phosphoribosyl-AMP cyclohydrolase [Streptomyces tsukubaensis].	55.36	112	50	0	1	112	1	112	2e-36	132
rs:WP_010157326	phosphoribosyl-AMP cyclohydrolase [Leucobacter chromiiresistens].	60.58	104	41	0	9	112	13	116	2e-36	132
tr:A0A0A8QMR7_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	62.11	95	36	0	18	112	34	128	2e-36	132
rs:WP_013888210	phosphoribosyl-AMP cyclohydrolase [Corynebacterium resistens].	63.16	95	35	0	18	112	16	110	2e-36	132
rs:WP_042423249	phosphoribosyl-AMP cyclohydrolase [Streptacidiphilus anmyonensis].	63.16	95	35	0	18	112	21	115	2e-36	132
rs:WP_016501991	phosphoribosyl-AMP cyclohydrolase [Pseudomonas putida].	55.26	114	50	1	18	130	8	121	2e-36	132
rs:WP_008439510	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. Ag1].	54.24	118	52	1	2	117	8	125	2e-36	132
rs:WP_036506253	phosphoribosyl-AMP cyclohydrolase [Nitrincola sp. AK23].	53.57	112	52	0	5	116	12	123	2e-36	132
rs:WP_028239343	phosphoribosyl-AMP cyclohydrolase [Pseudomonas azotifigens].	60.95	105	40	1	17	121	24	127	2e-36	132
tr:J8S0S1_PSEPU	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.27	110	46	1	16	125	36	144	3e-36	133
rs:WP_037826249	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL B-1347].	55.17	116	51	1	2	116	4	119	3e-36	132
rs:WP_020119948	phosphoribosyl-AMP cyclohydrolase [Streptomyces canus].	52.42	124	56	2	1	121	1	124	3e-36	132
rs:WP_015178735	phosphoribosyl-AMP cyclohydrolase [Oscillatoria nigro-viridis].	60.00	100	39	1	18	116	11	110	3e-36	132
rs:WP_038678406	phosphoribosyl-AMP cyclohydrolase [Pimelobacter simplex].	59.80	102	41	0	18	119	12	113	3e-36	131
sp:HIS3_AZOVD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	51.75	114	54	1	18	130	8	121	3e-36	132
rs:WP_010207645	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	59.41	101	41	0	17	117	25	125	3e-36	132
tr:A0A0A8R640_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	62.11	95	36	0	18	112	34	128	3e-36	132
rs:WP_035113376	phosphoribosyl-AMP cyclohydrolase [Corynebacterium auriscanis].	63.16	95	35	0	18	112	15	109	3e-36	132
rs:WP_046499748	phosphoribosyl-ATP pyrophosphatase [Syntrophomonas zehnderi].	52.54	118	51	2	17	130	4	120	3e-36	134
rs:WP_011293548	phosphoribosyl-ATP pyrophosphatase [Prochlorococcus marinus].	53.39	118	49	2	13	129	2	114	3e-36	134
rs:WP_016667607	phosphoribosyl-AMP cyclohydrolase [Propionibacterium sp. HGH0353].	55.56	108	47	1	6	112	8	115	3e-36	132
rs:WP_019472588	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	55.26	114	50	1	18	130	8	121	3e-36	132
rs:WP_030748284	phosphoribosyl-AMP cyclohydrolase [Streptomyces griseus].	61.62	99	38	0	18	116	19	117	3e-36	132
rs:WP_030464595	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomycetaceae].	62.11	95	36	0	18	112	21	115	3e-36	132
rs:WP_045950217	phosphoribosyl-AMP cyclohydrolase [Streptomyces katrae].	62.11	95	36	0	18	112	17	111	3e-36	132
rs:WP_023945453	phosphoribosyl-AMP cyclohydrolase [Gluconobacter frateurii].	61.90	105	39	1	9	113	9	112	3e-36	132
rs:WP_030209379	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-87].	62.11	95	36	0	18	112	18	112	3e-36	132
rs:WP_030205425	phosphoribosyl-AMP cyclohydrolase [Streptomyces bikiniensis].	62.11	95	36	0	18	112	13	107	3e-36	131
tr:A0A099T1B9_METMT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	56.19	105	46	0	13	117	2	106	3e-36	132
rs:WP_043295378	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. HMP271].	54.39	114	51	1	18	130	7	120	3e-36	132
rs:WP_028513665	hypothetical protein [Ruminococcaceae bacterium AE2021].	60.40	101	40	0	18	118	269	369	3e-36	138
rs:WP_035539614	phosphoribosyl-AMP cyclohydrolase [Halomonas sp. GFAJ-1].	54.87	113	50	1	18	129	32	144	3e-36	132
rs:WP_015582724	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Propionibacterium].	60.00	95	38	0	18	112	21	115	3e-36	132
rs:WP_003237374	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens group].	54.39	114	51	1	18	130	8	121	3e-36	132
rs:WP_012520978	phosphoribosyl-AMP cyclohydrolase [Phenylobacterium zucineum].	62.14	103	37	1	19	119	22	124	3e-36	132
rs:WP_018117470	hypothetical protein [Corynebacterium mastitidis].	58.10	105	44	0	18	122	16	120	3e-36	132
rs:WP_035749071	phosphoribosyl-AMP cyclohydrolase [Glycomyces sp. NRRL B-16210].	57.73	97	41	0	16	112	12	108	3e-36	131
rs:WP_018533127	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. HmicA12].	56.25	112	48	1	2	112	1	112	3e-36	132
rs:WP_027908584	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. URMO17WK12:I4].	54.78	115	51	1	17	130	7	121	3e-36	132
rs:WP_026395459	imidazole glycerol phosphate synthase [Acetobacterium dehalogenans].	55.45	101	45	0	13	113	1	101	3e-36	134
rs:WP_030402206	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-5555].	63.16	95	35	0	18	112	24	118	3e-36	132
rs:WP_042571093	phosphoribosyl-AMP cyclohydrolase [Pseudomonas simiae].	59.41	101	41	0	17	117	25	125	3e-36	132
tr:A0A0C5V8U2_PROFF	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	62.11	95	36	0	18	112	40	134	3e-36	132
rs:WP_043729713	phosphoribosyl-AMP cyclohydrolase [Streptomyces zinciresistens].	63.16	95	35	0	18	112	20	114	3e-36	132
rs:WP_037678845	phosphoribosyl-AMP cyclohydrolase [Streptomyces albus].	63.16	95	35	0	18	112	32	126	3e-36	132
rs:WP_010168408	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. PAMC 25886].	53.39	118	53	1	2	117	8	125	3e-36	132
tr:G2G975_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	63.16	95	35	0	18	112	23	117	3e-36	132
rs:WP_037868198	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-813].	61.54	104	38	1	18	119	5	108	3e-36	131
rs:WP_017947484	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	62.11	95	36	0	18	112	16	110	3e-36	131
rs:WP_006977927	phosphoribosyl-AMP cyclohydrolase [Chthoniobacter flavus].	59.18	98	40	0	16	113	4	101	3e-36	132
rs:WP_039819326	phosphoribosyl-AMP cyclohydrolase, partial [Streptomyces xinghaiensis].	62.11	95	36	0	18	112	31	125	3e-36	132
rs:WP_016875246	phosphoribosyl-AMP cyclohydrolase [Chlorogloeopsis fritschii].	61.39	101	38	1	18	117	11	111	3e-36	132
rs:WP_028325572	phosphoribosyl-AMP cyclohydrolase [Desulfatirhabdium butyrativorans].	54.24	118	51	3	17	131	3	120	3e-36	132
rs:WP_037926809	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. PCS3-D2].	62.11	95	36	0	18	112	18	112	3e-36	132
rs:WP_021108500	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Propionibacterium].	60.00	95	38	0	18	112	21	115	3e-36	132
rs:WP_036132545	phosphoribosyl-AMP cyclohydrolase [Marinobacter sp. AK21].	56.31	103	44	1	18	119	17	119	3e-36	132
rs:WP_046739692	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. AG1].	48.84	129	64	1	2	128	10	138	3e-36	132
rs:WP_019226655	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Dehalobacter].	50.86	116	55	1	2	115	1	116	3e-36	134
rs:WP_006456474	phosphoribosyl-ATP pyrophosphatase [Synechococcus sp. PCC 7335].	57.94	107	44	1	18	123	13	119	3e-36	134
rs:WP_044195348	imidazole glycerol phosphate synthase [Oscillatoria acuminata].	52.59	116	54	1	1	115	1	116	3e-36	134
rs:WP_006653366	phosphoribosyl-AMP cyclohydrolase [Natrialba hulunbeirensis].	58.00	100	42	0	18	117	9	108	3e-36	132
rs:WP_041838955	phosphoribosyl-AMP cyclohydrolase [Acidovorax ebreus].	50.43	117	54	1	18	130	7	123	3e-36	132
rs:WP_030745679	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-5135].	63.16	95	35	0	18	112	10	104	3e-36	131
rs:WP_045702046	phosphoribosyl-AMP cyclohydrolase [Streptomyces rubellomurinus].	63.16	95	35	0	18	112	21	115	3e-36	131
rs:WP_037746287	phosphoribosyl-AMP cyclohydrolase, partial [Streptomyces sp. CNT372].	55.36	112	49	1	2	112	1	112	3e-36	132
tr:K1XPE0_9BACT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	62.89	97	35	1	24	119	22	118	3e-36	132
rs:WP_016309074	phosphoribosyl-AMP cyclohydrolase [Enterorhabdus caecimuris].	59.41	101	41	0	13	113	1	101	3e-36	131
rs:WP_008455996	phosphoribosyl-AMP cyclohydrolase [Natrinema gari].	57.94	107	44	1	11	117	1	106	3e-36	131
rs:WP_030994614	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-5630].	57.27	110	46	1	4	112	2	111	3e-36	131
rs:WP_007381374	phosphoribosyl-AMP cyclohydrolase [Streptomyces sviceus].	52.42	124	56	2	1	121	1	124	3e-36	132
tr:G1USY0_9DELT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	55.93	118	47	2	4	120	8	121	3e-36	132
rs:WP_030391405	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomycetaceae].	63.16	95	35	0	18	112	21	115	3e-36	131
tr:W2DZW9_9PSED	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	55.36	112	48	1	8	117	10	121	3e-36	132
tr:U7A6M7_9PSED	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.39	114	51	1	18	130	8	121	3e-36	132
rs:WP_012721796	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	54.39	114	51	1	18	130	8	121	3e-36	132
rs:WP_033897735	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. FH1].	54.39	114	51	1	18	130	8	121	3e-36	132
rs:WP_033213125	phosphoribosyl-AMP cyclohydrolase [Kitasatospora phosalacinea].	62.11	95	36	0	18	112	21	115	3e-36	131
rs:WP_018401336	phosphoribosyl-AMP cyclohydrolase [gamma proteobacterium SCGC AB-629-P17].	48.70	115	58	1	17	130	6	120	3e-36	131
rs:WP_036941380	phosphoribosyl-AMP cyclohydrolase [Propionibacterium freudenreichii].	62.11	95	36	0	18	112	12	106	3e-36	131
rs:WP_030692585	phosphoribosyl-AMP cyclohydrolase [Streptomyces globisporus].	64.21	95	34	0	18	112	19	113	3e-36	131
rs:WP_028103544	phosphoribosyl-AMP cyclohydrolase [Pseudoduganella violaceinigra].	50.00	116	57	1	16	130	16	131	3e-36	132
rs:WP_039655940	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	62.11	95	36	0	18	112	21	115	3e-36	132
rs:WP_033897236	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. FH1].	59.41	101	41	0	17	117	25	125	4e-36	132
rs:WP_043261674	phosphoribosyl-AMP cyclohydrolase, partial [Streptomyces sp. e14].	54.47	123	52	2	2	120	4	126	4e-36	131
rs:WP_040795531	phosphoribosyl-AMP cyclohydrolase [Nocardia higoensis].	60.19	103	41	0	18	120	11	113	4e-36	131
rs:WP_026648967	phosphoribosyl-AMP cyclohydrolase [Blautia wexlerae].	58.25	103	42	1	16	117	14	116	4e-36	131
sp:HIS3_SALRD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	60.61	99	39	0	20	118	11	109	4e-36	131
rs:WP_027904345	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. URMO17WK12:I3].	54.78	115	51	1	17	130	7	121	4e-36	132
tr:F6FTU1_ISOV2	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	62.89	97	36	0	16	112	15	111	4e-36	131
rs:WP_045823038	phosphoribosyl-AMP cyclohydrolase [Williamsia sp. ARP1].	61.05	95	37	0	18	112	12	106	4e-36	131
rs:WP_037719691	phosphoribosyl-AMP cyclohydrolase [Streptomyces mirabilis].	52.42	124	56	2	1	121	1	124	4e-36	132
rs:WP_045938149	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-495].	63.16	95	35	0	18	112	21	115	4e-36	131
rs:WP_023009608	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Marinobacter].	56.31	103	44	1	18	119	17	119	4e-36	132
sp:HIS3_BORPD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	57.69	104	43	1	18	120	11	114	4e-36	132
rs:WP_006055644	phosphoribosyl-AMP cyclohydrolase [Halogeometricum borinquense].	57.69	104	43	1	18	121	7	109	4e-36	131
rs:WP_013822780	phosphoribosyl-ATP pyrophosphatase [Desulfotomaculum kuznetsovii].	60.19	103	41	0	11	113	1	103	4e-36	135
rs:WP_017253527	phosphoribosyl-AMP cyclohydrolase [Pseudomonas tolaasii].	58.42	101	42	0	17	117	25	125	4e-36	132
rs:WP_008905178	phosphoribosyl-AMP cyclohydrolase [Acidovorax sp. NO-1].	49.58	119	56	1	16	130	5	123	4e-36	131
rs:WP_040891297	phosphoribosyl-AMP cyclohydrolase, partial [Streptomyces mobaraensis].	62.11	95	36	0	18	112	10	104	4e-36	131
rs:WP_016971720	phosphoribosyl-AMP cyclohydrolase [Pseudomonas tolaasii].	58.42	101	42	0	17	117	25	125	4e-36	132
rs:WP_026397861	phosphoribosyl-AMP cyclohydrolase [Acetobacter nitrogenifigens].	52.63	114	54	0	10	123	8	121	4e-36	132
rs:WP_028803151	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. 142MFCol3.1].	55.45	110	48	1	4	112	6	115	4e-36	132
rs:WP_023845066	phosphoribosyl-AMP cyclohydrolase [Methanolobus tindarius].	60.58	104	39	2	18	121	7	108	4e-36	131
rs:WP_039582725	phosphoribosyl-AMP cyclohydrolase [Pseudomonas parafulva].	55.26	114	50	1	18	130	8	121	4e-36	131
rs:WP_005578426	phosphoribosyl-AMP cyclohydrolase [Natronobacterium gregoryi].	57.69	104	44	0	14	117	3	106	4e-36	131
rs:WP_030824597	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	62.11	95	36	0	18	112	18	112	4e-36	131
rs:WP_017884545	phosphoribosyl-AMP cyclohydrolase [Leucobacter sp. UCD-THU].	61.22	98	38	0	15	112	8	105	4e-36	131
rs:WP_046592705	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. MUSC149T].	58.49	106	42	1	18	121	18	123	4e-36	131
rs:WP_006850871	phosphoribosyl-ATP pyrophosphatase [Synechococcus sp. WH 8109].	64.95	97	33	1	18	113	12	108	4e-36	134
rs:WP_030662139	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	62.11	95	36	0	18	112	18	112	4e-36	131
rs:WP_035384146	phosphoribosyl-AMP cyclohydrolase [Ferriphaselus sp. R-1].	54.37	103	46	1	16	117	7	109	4e-36	131
rs:WP_011359711	phosphoribosyl-ATP pyrophosphatase [Synechococcus sp. CC9902].	65.66	99	33	1	16	113	10	108	4e-36	134
rs:WP_036937299	phosphoribosyl-AMP cyclohydrolase [Propionibacterium acidipropionici].	57.73	97	41	0	16	112	12	108	4e-36	131
rs:WP_030385540	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-241].	62.11	95	36	0	18	112	18	112	4e-36	131
rs:WP_041294807	phosphoribosyl-AMP cyclohydrolase [Isoptericola variabilis].	64.21	95	34	0	18	112	20	114	4e-36	131
tr:K7RXB7_PROA4	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.73	97	41	0	16	112	9	105	4e-36	131
rs:WP_027901650	phosphoribosyl-AMP cyclohydrolase [Pseudomonas syringae].	54.39	114	51	1	18	130	8	121	4e-36	131
rs:WP_014862960	phosphoribosyl-AMP cyclohydrolase [Natrinema sp. J7-2].	57.94	107	44	1	11	117	1	106	4e-36	131
rs:WP_044870808	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. LFM046].	54.39	114	51	1	18	130	8	121	4e-36	131
rs:WP_030743602	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-31].	59.05	105	42	1	9	112	11	115	4e-36	131
rs:WP_015043475	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Dehalobacter].	50.00	116	56	1	2	115	1	116	4e-36	134
rs:WP_016489562	phosphoribosyl-AMP cyclohydrolase [Pseudomonas putida].	54.39	114	51	1	18	130	8	121	4e-36	131
rs:WP_040086164	phosphoribosyl-AMP cyclohydrolase [Corynebacterium humireducens].	64.21	95	34	0	18	112	19	113	4e-36	131
tr:A0A022MIM7_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	63.16	95	35	0	18	112	21	115	4e-36	132
rs:WP_034016218	phosphoribosyl-AMP cyclohydrolase [Pseudomonas aeruginosa].	54.39	114	51	1	18	130	8	121	4e-36	131
rs:WP_008569471	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. Chol1].	54.39	114	51	1	18	130	7	120	4e-36	131
rs:WP_037725795	phosphoribosyl-AMP cyclohydrolase, partial [Streptomyces sp. Amel2xE9].	56.25	112	48	1	2	112	4	115	4e-36	131
rs:WP_006183183	phosphoribosyl-AMP cyclohydrolase [Natrinema pellirubrum].	57.43	101	43	0	17	117	6	106	4e-36	131
rs:WP_021899256	phosphoribosyl-AMP cyclohydrolase [Eggerthella sp. CAG:1427].	53.85	117	49	1	2	113	6	122	4e-36	131
rs:WP_023632585	phosphoribosyl-AMP cyclohydrolase [Pseudomonas mosselii].	54.39	114	51	1	18	130	8	121	4e-36	131
rs:WP_038845442	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	59.41	101	41	0	17	117	25	125	4e-36	132
rs:WP_004953437	hypothetical protein [Acinetobacter junii].	53.51	114	51	1	2	113	10	123	4e-36	132
rs:WP_026437583	phosphoribosyl-AMP cyclohydrolase [Acidovorax sp. JHL-9].	48.74	119	57	1	16	130	5	123	5e-36	131
rs:WP_041629950	phosphoribosyl-AMP cyclohydrolase [Corynebacterium variabile].	51.30	115	53	1	1	112	1	115	5e-36	131
rs:WP_021886384	phosphoribosyl-ATP diphosphatase [Clostridium sp. CAG:590].	60.38	106	40	1	9	114	211	314	5e-36	138
rs:WP_043518171	phosphoribosyl-AMP cyclohydrolase [Halomonas sp. BC04].	51.94	129	55	2	4	125	5	133	5e-36	131
rs:WP_033348466	phosphoribosyl-AMP cyclohydrolase [Streptomyces aureofaciens].	63.16	95	35	0	18	112	21	115	5e-36	131
rs:WP_003286706	phosphoribosyl-AMP cyclohydrolase [Pseudomonas stutzeri].	54.39	114	51	1	18	130	7	120	5e-36	131
rs:WP_020877326	phosphoribosyl-AMP cyclohydrolase [Desulfococcus multivorans].	59.09	110	41	3	18	125	4	111	5e-36	131
rs:WP_017849884	phosphoribosyl-AMP cyclohydrolase [Pseudomonas veronii].	53.51	114	52	1	18	130	8	121	5e-36	131
rs:WP_031148330	phosphoribosyl-AMP cyclohydrolase [Streptomyces xanthophaeus].	62.11	95	36	0	18	112	18	112	5e-36	131
sp:HIS3_ACIET	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.43	117	54	1	18	130	10	126	5e-36	131
rs:WP_041434560	imidazole glycerol phosphate synthase [Synechococcus sp. CC9605].	64.95	97	33	1	18	113	12	108	5e-36	134
rs:WP_014135197	phosphoribosyl-AMP cyclohydrolase [Kitasatospora setae].	62.11	95	36	0	18	112	21	115	5e-36	131
rs:WP_033269397	phosphoribosyl-AMP cyclohydrolase [Streptomyces lydicus].	63.16	95	35	0	18	112	20	114	5e-36	131
rs:WP_009615405	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	53.51	114	52	1	18	130	8	121	5e-36	131
rs:WP_039895605	phosphoribosyl-AMP cyclohydrolase [Lyngbya sp. PCC 8106].	63.37	101	36	1	17	116	10	110	5e-36	131
tr:D4M5S9_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	58.26	115	46	1	2	116	214	326	5e-36	138
rs:WP_017528642	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	52.54	118	54	1	2	117	8	125	5e-36	131
rs:WP_036977199	phosphoribosyl-AMP cyclohydrolase, partial [Propionibacterium granulosum].	62.22	90	34	0	18	107	5	94	5e-36	130
rs:WP_042432817	phosphoribosyl-AMP cyclohydrolase [Senegalimassilia anaerobia].	58.33	108	44	1	11	117	1	108	5e-36	130
rs:WP_008702994	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Clostridiales].	58.16	98	41	0	16	113	14	111	5e-36	131
rs:WP_007109946	phosphoribosyl-AMP cyclohydrolase [Natrinema altunense].	57.94	107	44	1	11	117	1	106	5e-36	131
tr:A0YLL5_LYNSP	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	63.37	101	36	1	17	116	11	111	5e-36	131
rs:WP_031083733	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	62.11	95	36	0	18	112	24	118	5e-36	131
rs:WP_018016803	hypothetical protein [Corynebacterium capitovis].	54.03	124	51	2	2	119	6	129	5e-36	131
rs:WP_042544242	phosphoribosyl-AMP cyclohydrolase [Leucobacter komagatae].	61.86	97	37	0	16	112	6	102	5e-36	131
tr:F9NT98_PROAA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.55	106	43	1	18	121	16	121	5e-36	131
rs:WP_036936303	imidazole glycerol phosphate synthase [Pseudobacteroides cellulosolvens].	55.34	103	46	0	11	113	1	103	5e-36	134
rs:WP_022988337	phosphoribosyl-AMP cyclohydrolase [Marinobacter sp. ES-1].	56.31	103	44	1	18	119	17	119	5e-36	131
rs:WP_030783551	phosphoribosyl-AMP cyclohydrolase [Streptomyces lavenduligriseus].	62.11	95	36	0	18	112	21	115	5e-36	131
rs:WP_037055585	phosphoribosyl-AMP cyclohydrolase [Pseudomonas oleovorans].	55.56	108	48	0	18	125	28	135	5e-36	131
tr:R6Q4A7_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	58.26	115	46	1	2	116	214	326	5e-36	138
rs:WP_029149921	phosphoribosyl-AMP cyclohydrolase [Microbacterium indicum].	58.10	105	39	1	18	122	15	114	5e-36	131
rs:WP_030492948	phosphoribosyl-AMP cyclohydrolase [Microtetraspora glauca].	60.61	99	39	0	18	116	19	117	5e-36	131
rs:WP_030347827	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-1022].	63.16	95	35	0	18	112	21	115	5e-36	131
rs:WP_016978685	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	59.41	101	41	0	17	117	25	125	5e-36	131
rs:WP_019885480	phosphoribosyl-AMP cyclohydrolase [Streptomyces purpureus].	62.11	95	36	0	18	112	16	110	5e-36	131
rs:WP_030605388	phosphoribosyl-AMP cyclohydrolase [Streptomyces achromogenes].	62.11	95	36	0	18	112	21	115	5e-36	131
rs:WP_030318903	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL B-3229].	52.85	123	55	2	1	120	1	123	6e-36	131
tr:U1F291_9ACTO	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:ERF58057.1}; EC=3.5.4.19 {ECO:0000313|EMBL:ERF58057.1}; Flags: Fragment;	62.22	90	34	0	18	107	54	143	6e-36	132
tr:K9TM08_9CYAN	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	59.60	99	39	1	18	115	13	111	6e-36	134
tr:A0A074LNB8_9BACL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	59.79	97	39	0	17	113	3	99	6e-36	134
rs:WP_017526550	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	53.51	114	52	1	18	130	8	121	6e-36	131
rs:WP_035145922	phosphoribosyl-ATP pyrophosphatase [Caldicoprobacter oshimai].	61.46	96	37	0	18	113	6	101	6e-36	135
rs:WP_037894054	phosphoribosyl-AMP cyclohydrolase, partial [Streptomyces sp. Tu 6176].	63.16	95	35	0	18	112	21	115	6e-36	131
rs:WP_010169173	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	54.39	114	51	1	18	130	8	121	6e-36	131
rs:WP_028618553	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. 2-92(2010)].	59.41	101	41	0	17	117	25	125	6e-36	131
rs:WP_043887682	phosphoribosyl-AMP cyclohydrolase [Methylophaga thiooxydans].	57.84	102	43	0	17	118	22	123	6e-36	131
rs:WP_028822463	phosphoribosyl-AMP cyclohydrolase [Propionimicrobium lymphophilum].	61.62	99	38	0	16	114	9	107	6e-36	130
rs:WP_014554966	phosphoribosyl-AMP cyclohydrolase [Haloquadratum walsbyi].	56.73	104	44	1	18	121	17	119	6e-36	131
rs:WP_015155764	phosphoribosyl-AMP cyclohydrolase [Chroococcidiopsis thermalis].	59.00	100	40	1	18	116	17	116	6e-36	130
rs:WP_015818413	phosphoribosyl-AMP cyclohydrolase [Teredinibacter turnerae].	55.34	103	45	1	18	119	11	113	6e-36	131
tr:A0A0A7GI61_9EURY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	52.83	106	50	0	18	123	3	108	6e-36	130
tr:A0A066Z7G8_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	62.11	95	36	0	18	112	24	118	6e-36	131
rs:WP_016641802	phosphoribosyl-AMP cyclohydrolase [Streptomyces aurantiacus].	54.46	112	50	1	2	112	1	112	6e-36	131
rs:WP_036542453	phosphoribosyl-AMP cyclohydrolase [Nocardioides sp. UNC345MFTsu5.1].	61.05	95	37	0	18	112	12	106	6e-36	130
rs:WP_007263570	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. C].	61.05	95	37	0	18	112	17	111	6e-36	130
rs:WP_037873614	phosphoribosyl-AMP cyclohydrolase, partial [Streptomyces sp. PsTaAH-124].	63.16	95	35	0	18	112	21	115	6e-36	131
rs:WP_024537809	phosphoribosyl-AMP cyclohydrolase [Comamonas badia].	50.42	119	55	1	16	130	10	128	6e-36	131
rs:WP_010462068	phosphoribosyl-AMP cyclohydrolase [Acidovorax radicis].	49.58	119	56	1	16	130	5	123	6e-36	131
rs:WP_002725826	phosphoribosyl-AMP cyclohydrolase [Phaeospirillum molischianum].	62.63	99	37	0	18	116	14	112	6e-36	131
rs:WP_006431950	phosphoribosyl-AMP cyclohydrolase [Natrinema versiforme].	57.94	107	44	1	11	117	1	106	6e-36	130
rs:WP_035850308	phosphoribosyl-AMP cyclohydrolase [Kitasatospora azatica].	62.11	95	36	0	18	112	25	119	6e-36	131
rs:WP_037796430	phosphoribosyl-AMP cyclohydrolase [Streptomyces peruviensis].	58.49	106	42	1	18	121	20	125	6e-36	131
rs:WP_036907014	imidazole glycerol phosphate synthase [Prochlorococcus marinus].	53.39	118	49	2	13	129	2	114	7e-36	133
rs:WP_024716786	phosphoribosyl-AMP cyclohydrolase [Gluconobacter oxydans].	60.95	105	40	1	9	113	9	112	7e-36	131
rs:WP_031057050	phosphoribosyl-AMP cyclohydrolase [Streptomyces ochraceiscleroticus].	62.11	95	36	0	18	112	23	117	7e-36	131
rs:WP_030281664	phosphoribosyl-AMP cyclohydrolase [Streptomyces catenulae].	62.11	95	36	0	18	112	27	121	7e-36	131
rs:WP_037577422	phosphoribosyl-AMP cyclohydrolase [Streptacidiphilus oryzae].	59.05	105	38	1	18	122	17	116	7e-36	130
rs:WP_031035920	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-5650].	62.11	95	36	0	18	112	24	118	7e-36	131
sp:HIS3_MARHV	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	56.31	103	44	1	18	119	17	119	7e-36	131
rs:WP_042842593	phosphoribosyl-AMP cyclohydrolase [Propionibacterium acnes].	57.55	106	43	1	18	121	19	124	7e-36	131
rs:WP_034908657	phosphoribosyl-AMP cyclohydrolase [[Eubacterium] cellulosolvens].	59.38	96	39	0	18	113	11	106	7e-36	130
rs:WP_037669583	phosphoribosyl-AMP cyclohydrolase [Streptomyces griseus].	58.49	106	42	1	18	121	5	110	7e-36	130
rs:WP_035861522	phosphoribosyl-AMP cyclohydrolase [Kitasatospora cheerisanensis].	62.11	95	36	0	18	112	21	115	7e-36	130
rs:WP_044902829	imidazole glycerol phosphate synthase [Lachnospiraceae bacterium P6B14].	64.44	90	32	0	25	114	1	90	7e-36	133
rs:WP_019433601	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. AA0539].	62.11	95	36	0	18	112	16	110	7e-36	130
rs:WP_010356514	phosphoribosyl-AMP cyclohydrolase [Streptomyces acidiscabies].	63.16	95	35	0	18	112	21	115	7e-36	130
rs:WP_022071342	phosphoribosyl-AMP cyclohydrolase [Clostridium bartlettii CAG:1329].	54.55	110	49	1	8	116	6	115	7e-36	130
rs:WP_033311002	phosphoribosyl-AMP cyclohydrolase [Streptomyces iakyrus].	59.05	105	41	1	18	120	16	120	7e-36	130
rs:WP_011823360	phosphoribosyl-ATP pyrophosphatase [Prochlorococcus marinus].	53.39	118	49	2	13	129	2	114	7e-36	133
rs:WP_028948672	imidazole glycerol phosphate synthase [Synechocystis sp. PCC 6714].	56.88	109	44	2	8	115	9	115	7e-36	133
rs:WP_037948898	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. PRh5].	63.16	95	35	0	18	112	18	112	8e-36	130
rs:WP_024766215	phosphoribosyl-AMP cyclohydrolase [Pseudomonas nitroreducens].	55.26	114	50	1	18	130	8	121	8e-36	131
rs:WP_038093369	phosphoribosyl-ATP pyrophosphatase [Tumebacillus flagellatus].	59.79	97	39	0	17	113	9	105	8e-36	133
rs:WP_037024673	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. 20_BN].	52.63	114	53	1	18	130	7	120	8e-36	131
rs:WP_037937731	phosphoribosyl-AMP cyclohydrolase [Streptomyces toyocaensis].	62.11	95	36	0	18	112	35	129	8e-36	131
rs:WP_017872993	hypothetical protein [Candidatus Caldatribacterium saccharofermentans].	59.00	100	41	0	18	117	7	106	8e-36	134
rs:WP_030724538	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-237].	62.11	95	36	0	18	112	18	112	8e-36	130
rs:WP_030314594	phosphoribosyl-AMP cyclohydrolase [Streptomyces flavochromogenes].	62.11	95	36	0	18	112	19	113	8e-36	130
rs:WP_021132486	phosphoribosyl-AMP cyclohydrolase [Phaeospirillum fulvum].	62.63	99	37	0	18	116	14	112	8e-36	131
rs:WP_047232848	phosphoribosyl-AMP cyclohydrolase [Cellulosimicrobium funkei].	62.11	95	36	0	18	112	22	116	8e-36	131
rs:WP_016573050	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	62.11	95	36	0	18	112	19	113	8e-36	130
rs:WP_023049299	phosphoribosyl-AMP cyclohydrolase [Pseudomonas putida].	54.39	114	51	1	18	130	8	121	8e-36	130
rs:WP_017520157	phosphoribosyl-AMP cyclohydrolase [Pseudomonas nitroreducens].	55.26	114	50	1	18	130	8	121	8e-36	131
rs:WP_020492629	phosphoribosyl-ATP pyrophosphatase [Dehalobacter sp. FTH1].	51.72	116	54	1	2	115	1	116	8e-36	134
rs:WP_008386301	phosphoribosyl-amp cyclohydrolase [Halosarcina pallida].	57.41	108	45	1	14	121	3	109	8e-36	130
rs:WP_028809618	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. 351MFTsu5.1].	52.85	123	55	2	1	120	1	123	8e-36	130
rs:WP_005082493	hypothetical protein [Acinetobacter haemolyticus].	52.63	114	52	1	2	113	10	123	8e-36	131
rs:WP_008738608	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. Mg1].	61.05	95	37	0	18	112	17	111	8e-36	130
tr:A0A0D6NA53_9PROT	SubName: Full=Phosphoribosyl AMP cyclohydrolase {ECO:0000313|EMBL:GAN62453.1};	55.96	109	48	0	9	117	9	117	8e-36	131
tr:N9N423_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	53.70	108	48	1	8	113	2	109	8e-36	130
rs:WP_002518964	phosphoribosyl-AMP cyclohydrolase [Propionibacterium acnes].	53.10	113	52	1	1	112	1	113	8e-36	130
rs:WP_017406167	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Delftia].	50.43	117	54	1	18	130	7	123	8e-36	130
rs:WP_020935098	phosphoribosyl-AMP cyclohydrolase [Corynebacterium maris].	62.11	95	36	0	18	112	20	114	8e-36	130
tr:Q3AKX0_SYNSC	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	64.95	97	33	1	18	113	29	125	8e-36	134
rs:WP_042818641	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. RSD-27].	61.05	95	37	0	18	112	17	111	9e-36	130
rs:WP_037004546	phosphoribosyl-AMP cyclohydrolase [Pseudomonas pseudoalcaligenes].	52.63	114	53	1	18	130	8	121	9e-36	130
rs:WP_035805418	phosphoribosyl-AMP cyclohydrolase [Kitasatospora mediocidica].	61.05	95	37	0	18	112	25	119	9e-36	130
rs:WP_043152176	phosphoribosyl-AMP cyclohydrolase [Pseudomonas aeruginosa].	54.39	114	51	1	18	130	8	121	9e-36	130
rs:WP_019161775	phosphoribosyl-AMP cyclohydrolase [Ruminococcus sp. JC304].	58.33	96	40	0	18	113	21	116	9e-36	130
rs:WP_026381971	phosphoribosyl-AMP cyclohydrolase [Afifella pfennigii].	58.18	110	44	1	19	126	16	125	9e-36	130
rs:WP_028468589	phosphoribosyl-AMP cyclohydrolase [Neptunomonas japonica].	53.98	113	50	1	5	117	14	124	9e-36	130
rs:WP_007114249	phosphoribosyl-AMP cyclohydrolase [Halomonas boliviensis].	53.91	115	53	0	16	130	33	147	9e-36	131
tr:A0A081XMA6_STRTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	62.11	95	36	0	18	112	38	132	9e-36	131
tr:B8J3P0_DESDA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.89	121	55	2	1	120	1	120	9e-36	131
rs:WP_012113671	phosphoribosyl-AMP cyclohydrolase [Xanthobacter autotrophicus].	55.56	117	49	2	7	120	16	132	9e-36	132
rs:WP_008930907	phosphoribosyl-AMP cyclohydrolase [Ectothiorhodospira sp. PHS-1].	58.25	103	42	1	18	119	10	112	9e-36	130
rs:WP_027178294	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio bastinii].	61.86	97	36	1	24	119	11	107	9e-36	130
rs:WP_030850960	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-4474].	61.05	95	37	0	18	112	18	112	1e-35	130
rs:WP_003960150	phosphoribosyl-AMP cyclohydrolase [Streptomyces clavuligerus].	62.11	95	36	0	18	112	23	117	1e-35	130
rs:WP_009397765	phosphoribosyl-AMP cyclohydrolase [Pseudomonas putida].	54.39	114	51	1	18	130	8	121	1e-35	130
rs:WP_017794429	hypothetical protein [Leucobacter salsicius].	59.22	103	40	1	12	112	3	105	1e-35	130
rs:WP_025239973	phosphoribosyl-AMP cyclohydrolase [Pseudomonas stutzeri].	53.51	114	52	1	18	130	7	120	1e-35	130
rs:WP_031166400	phosphoribosyl-AMP cyclohydrolase [Streptomyces durhamensis].	62.11	95	36	0	18	112	21	115	1e-35	130
rs:WP_034604051	hypothetical protein, partial [Cellulosimicrobium cellulans].	62.11	95	36	0	18	112	26	120	1e-35	130
rs:WP_023911929	phosphoribosyl-AMP cyclohydrolase [Pseudomonas aeruginosa].	54.39	114	51	1	18	130	8	121	1e-35	130
rs:WP_040368753	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio longus].	64.95	97	33	1	24	119	10	106	1e-35	130
rs:WP_033284496	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-525].	54.46	112	50	1	2	112	1	112	1e-35	131
sp:HIS3_CHLP8	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.89	112	55	0	17	128	14	125	1e-35	130
rs:WP_031629639	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	54.39	114	51	1	18	130	8	121	1e-35	130
rs:WP_021204920	phosphoribosyl-AMP cyclohydrolase [Pseudomonas aeruginosa].	54.39	114	51	1	18	130	8	121	1e-35	130
rs:WP_020026164	phosphoribosyl-AMP cyclohydrolase [gamma proteobacterium SCGC AAA076-D13].	48.28	116	59	1	16	130	5	120	1e-35	130
rs:WP_037782581	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. HGB0020].	62.11	95	36	0	18	112	21	115	1e-35	130
rs:WP_022057666	phosphoribosyl-ATP diphosphatase [Clostridium sp. CAG:167].	59.05	105	41	1	9	113	207	309	1e-35	137
tr:W0JMV8_9EURY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	53.85	104	48	0	14	117	3	106	1e-35	130
rs:WP_010039428	phosphoribosyl-AMP cyclohydrolase [Streptomyces chartreusis].	59.05	105	41	1	18	120	16	120	1e-35	130
rs:WP_018557174	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. BoleA5].	61.05	95	37	0	18	112	13	107	1e-35	130
rs:WP_043089243	phosphoribosyl-AMP cyclohydrolase [Pseudomonas aeruginosa].	54.39	114	51	1	18	130	8	121	1e-35	130
rs:WP_029040807	phosphoribosyl-AMP cyclohydrolase [Cucumibacter marinus].	57.26	117	43	3	19	131	25	138	1e-35	131
rs:WP_028422560	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. GXT6].	62.11	95	36	0	18	112	21	115	1e-35	130
rs:WP_031115710	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	56.36	110	45	1	18	124	19	128	1e-35	130
rs:WP_040436399	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Comamonadaceae].	49.57	117	55	1	18	130	7	123	1e-35	130
rs:WP_006110784	phosphoribosyl-AMP cyclohydrolase [Natrialba asiatica].	57.43	101	43	0	17	117	8	108	1e-35	130
rs:WP_020190662	phosphoribosyl-AMP cyclohydrolase [Pseudomonas putida].	58.00	100	42	0	18	117	23	122	1e-35	130
tr:A0A0A8S2K3_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	61.05	95	37	0	18	112	34	128	1e-35	131
rs:WP_034007469	phosphoribosyl-AMP cyclohydrolase [Pseudomonas aeruginosa].	54.39	114	51	1	18	130	8	121	1e-35	130
rs:WP_042383712	phosphoribosyl-AMP cyclohydrolase [Streptacidiphilus melanogenes].	62.11	95	36	0	18	112	21	115	1e-35	130
rs:WP_034110436	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	58.42	101	42	0	17	117	25	125	1e-35	130
rs:WP_036485844	imidazole glycerol phosphate synthase [Myxosarcina sp. GI1].	52.38	126	46	3	11	122	1	126	1e-35	134
rs:WP_010680937	phosphoribosyl-ATP pyrophosphatase [Acetivibrio cellulolyticus].	57.28	103	43	1	18	119	8	110	1e-35	133
rs:WP_027850824	phosphoribosyl-AMP cyclohydrolase [Marinospirillum insulare].	62.50	96	36	0	18	113	33	128	1e-35	131
tr:Q2JWX9_SYNJA	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	61.17	103	38	2	17	117	27	129	1e-35	133
rs:WP_037906076	phosphoribosyl-AMP cyclohydrolase [Streptomyces yeochonensis].	61.05	95	37	0	18	112	12	106	1e-35	130
tr:S2Y5Z8_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	62.11	95	36	0	18	112	18	112	1e-35	130
rs:WP_024355728	phosphoribosyl-AMP cyclohydrolase [Leucobacter chironomi].	61.22	98	38	0	15	112	8	105	1e-35	130
rs:WP_034595567	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. CIP-A165].	48.84	129	64	1	2	128	10	138	1e-35	130
rs:WP_017641041	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. 313].	55.34	103	45	1	18	119	8	110	1e-35	130
rs:WP_023542419	phosphoribosyl-AMP cyclohydrolase [Streptomyces niveus].	61.05	95	37	0	18	112	22	116	1e-35	130
rs:WP_009790054	phosphoribosyl-ATP pyrophosphatase [Synechococcus sp. BL107].	63.64	99	35	1	16	113	10	108	1e-35	133
sp:HIS3_PSEA8	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	54.39	114	51	1	18	130	8	121	1e-35	130
rs:WP_020210057	phosphoribosyl-AMP cyclohydrolase [Gilvimarinus chinensis].	49.21	126	62	2	6	130	2	126	1e-35	130
rs:WP_028238218	phosphoribosyl-AMP cyclohydrolase [Pseudomonas azotifigens].	53.51	114	52	1	18	130	7	120	1e-35	130
rs:WP_023395072	phosphoribosyl-AMP cyclohydrolase [Candidatus Halobonum tyrrellensis].	52.89	121	56	1	1	121	1	120	1e-35	130
rs:WP_041438826	imidazole glycerol phosphate synthase [Synechococcus sp. JA-3-3Ab].	61.17	103	38	2	17	117	10	112	1e-35	133
rs:WP_015853657	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio salexigens].	62.89	97	35	1	24	119	11	107	1e-35	130
rs:WP_043311116	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. ML96].	53.51	114	52	1	18	130	8	121	1e-35	130
rs:WP_003989579	phosphoribosyl-AMP cyclohydrolase [Streptomyces viridochromogenes].	59.62	104	40	1	18	119	19	122	1e-35	130
rs:WP_003110867	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	54.39	114	51	1	18	130	8	121	1e-35	130
rs:WP_030794024	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-5008].	62.11	95	36	0	18	112	21	115	1e-35	130
rs:WP_030773221	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	61.05	95	37	0	18	112	18	112	1e-35	130
tr:N8R984_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	48.84	129	64	1	2	128	12	140	1e-35	130
rs:WP_016455930	hypothetical protein [Propionimicrobium lymphophilum].	61.62	99	38	0	16	114	9	107	1e-35	130
rs:WP_005882373	phosphoribosyl-AMP cyclohydrolase [Oxalobacter formigenes].	55.67	97	43	0	17	113	9	105	1e-35	130
rs:WP_017489457	phosphoribosyl-AMP cyclohydrolase [Micrococcus luteus].	60.82	97	38	0	16	112	11	107	1e-35	130
rs:WP_022487849	phosphoribosyl-AMP cyclohydrolase [Acidaminococcus sp. CAG:542].	52.99	117	55	0	11	127	1	117	1e-35	133
rs:WP_004058935	phosphoribosyl-AMP cyclohydrolase [Haloferax mediterranei].	56.31	103	45	0	15	117	2	104	1e-35	130
rs:WP_004619986	phosphoribosyl-ATP pyrophosphatase [[Clostridium] papyrosolvens].	46.03	126	62	1	11	130	1	126	1e-35	132
rs:WP_042302628	phosphoribosyl-AMP cyclohydrolase [Burkholderia kururiensis].	50.39	127	55	3	4	126	8	130	1e-35	130
rs:WP_013378694	phosphoribosyl-ATP pyrophosphatase [Eubacterium limosum].	53.51	114	51	1	18	129	7	120	1e-35	132
rs:WP_005528809	phosphoribosyl-AMP cyclohydrolase [Corynebacterium striatum].	63.16	95	34	1	18	112	17	110	1e-35	130
rs:WP_007855732	phosphoribosyl-AMP cyclohydrolase [Acidovorax sp. CF316].	49.58	119	56	1	16	130	5	123	1e-35	130
rs:WP_008689608	phosphoribosyl-AMP cyclohydrolase [Eubacterium sp. 3_1_31].	59.57	94	38	0	24	117	11	104	1e-35	129
rs:WP_005987143	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio africanus].	56.25	112	48	1	20	130	6	117	1e-35	130
gp:AY657378_1	PA5066 [synthetic construct]	54.39	114	51	1	18	130	8	121	1e-35	130
sp:HIS3_ACISJ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	49.57	117	55	1	18	130	10	126	1e-35	130
rs:WP_013793288	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fulva].	53.91	115	52	1	17	130	7	121	1e-35	130
rs:WP_046775283	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. fd2-tb].	61.05	95	37	0	18	112	18	112	1e-35	130
rs:WP_034234359	hypothetical protein [Lachnospiraceae bacterium AC2029].	60.00	110	41	2	9	117	223	330	1e-35	137
rs:WP_028228094	phosphoribosyl-AMP cyclohydrolase [Burkholderia ferrariae].	56.19	105	45	1	18	121	15	119	1e-35	130
rs:WP_045542025	phosphoribosyl-AMP cyclohydrolase [Acetobacter tropicalis].	58.33	108	44	1	18	124	18	125	1e-35	130
rs:WP_013744178	phosphoribosyl-AMP cyclohydrolase [Pusillimonas sp. T7-7].	55.56	108	47	1	18	124	11	118	1e-35	130
rs:WP_024304362	phosphoribosyl-AMP cyclohydrolase [Pseudogulbenkiania sp. MAI-1].	52.63	114	53	1	18	130	7	120	1e-35	130
sp:HIS3_CHLTE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	55.34	103	46	0	17	119	14	116	1e-35	130
rs:WP_031149387	phosphoribosyl-AMP cyclohydrolase [Streptomyces erythrochromogenes].	61.05	95	37	0	18	112	18	112	1e-35	130
rs:WP_013684643	phosphoribosyl-AMP cyclohydrolase [Archaeoglobus veneficus].	56.44	101	44	0	18	118	2	102	1e-35	129
rs:WP_035380968	phosphoribosyl-AMP cyclohydrolase [Acetobacter tropicalis].	58.33	108	44	1	18	124	18	125	1e-35	130
rs:WP_030248302	phosphoribosyl-AMP cyclohydrolase [Streptacidiphilus jeojiense].	61.05	95	37	0	18	112	21	115	1e-35	130
sp:HIS3_PSEAB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	54.39	114	51	1	18	130	8	121	1e-35	130
rs:WP_037872216	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-37].	54.87	113	50	1	1	112	4	116	1e-35	130
rs:WP_032890216	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. RIT357].	54.39	114	51	1	18	130	8	121	1e-35	130
rs:WP_008978782	phosphoribosyl-AMP cyclohydrolase [Erysipelotrichaceae bacterium 5_2_54FAA].	59.57	94	38	0	24	117	11	104	1e-35	129
rs:WP_035940359	phosphoribosyl-AMP cyclohydrolase [Knoellia aerolata].	56.07	107	44	1	9	112	3	109	1e-35	130
rs:WP_035122592	phosphoribosyl-AMP cyclohydrolase [Corynebacterium freneyi].	63.16	95	35	0	18	112	9	103	1e-35	129
rs:WP_023922531	phosphoribosyl-ATP diphosphatase [Ruminococcus lactaris].	60.19	108	41	1	9	116	222	327	1e-35	137
rs:WP_027011970	phosphoribosyl-AMP cyclohydrolase [Corynebacterium freiburgense].	63.16	95	35	0	18	112	18	112	1e-35	130
rs:WP_016962735	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	53.51	114	52	1	18	130	8	121	1e-35	130
rs:WP_030966191	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-378].	61.05	95	37	0	18	112	21	115	1e-35	130
rs:WP_030820690	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-2305].	62.11	95	36	0	18	112	12	106	1e-35	130
rs:WP_046087890	phosphoribosyl-AMP cyclohydrolase [Streptomyces yogyakartensis].	62.11	95	36	0	18	112	18	112	1e-35	130
tr:W3RHE0_9BRAD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	58.25	103	42	1	19	120	34	136	1e-35	131
tr:D4HDT4_PROAS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	58.95	95	39	0	18	112	16	110	1e-35	130
rs:WP_042166036	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NBRC 110035].	62.11	95	36	0	18	112	21	115	1e-35	130
rs:WP_009775085	phosphoribosyl-AMP cyclohydrolase [Janibacter sp. HTCC2649].	59.18	98	40	0	15	112	12	109	1e-35	130
sp:HIS2_PROMA	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	58.25	103	42	1	18	119	12	114	2e-35	133
sp:HIS3_AZOCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.00	114	56	1	18	130	8	121	2e-35	130
sp:HIS31_PSEF5	RecName: Full=Phosphoribosyl-AMP cyclohydrolase 1 {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH 1 {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.51	114	52	1	18	130	8	121	2e-35	130
rs:WP_040014304	phosphoribosyl-AMP cyclohydrolase, partial [Dermacoccus sp. Ellin185].	59.79	97	39	0	18	114	18	114	2e-35	130
rs:WP_038247858	phosphoribosyl-AMP cyclohydrolase [Zetaproteobacteria bacterium TAG-1].	59.38	96	39	0	18	113	10	105	2e-35	130
rs:WP_010488551	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. S9].	54.39	114	51	1	18	130	8	121	2e-35	130
rs:WP_013242211	phosphoribosyl-AMP cyclohydrolase [Corynebacterium pseudotuberculosis].	64.21	95	33	1	18	112	19	112	2e-35	129
rs:WP_009095131	phosphoribosyl-AMP cyclohydrolase [Halomonas sp. GFAJ-1].	62.11	95	36	0	19	113	36	130	2e-35	130
rs:WP_029339346	phosphoribosyl-AMP cyclohydrolase [Geodermatophilaceae bacterium URHB0048].	55.96	109	47	1	9	116	5	113	2e-35	130
rs:WP_015389228	phosphoribosyl-AMP cyclohydrolase [Candidatus Kinetoplastibacterium galatii].	50.89	112	54	1	17	127	11	122	2e-35	130
rs:WP_036924491	phosphoribosyl-AMP cyclohydrolase [Propionibacterium thoenii].	57.73	97	41	0	16	112	9	105	2e-35	130
rs:WP_034472837	phosphoribosyl-AMP cyclohydrolase [Afipia sp. P52-10].	58.25	103	42	1	19	120	22	124	2e-35	130
rs:WP_045422522	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. MT-1].	53.51	114	52	1	18	130	7	120	2e-35	130
rs:WP_039637443	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. 769].	60.19	103	41	0	18	120	24	126	2e-35	130
sp:HIS3_CHLPD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.92	102	47	0	17	118	14	115	2e-35	130
rs:WP_028473691	phosphoribosyl-AMP cyclohydrolase [Nocardioides alkalitolerans].	62.11	95	36	0	18	112	12	106	2e-35	129
sp:HIS3_GLUOX	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	60.95	105	40	1	9	113	29	132	2e-35	130
rs:WP_015540371	phosphoribosyl-AMP cyclohydrolase [Gordonibacter pamelaeae].	58.42	101	42	0	13	113	1	101	2e-35	129
rs:WP_006528830	phosphoribosyl-AMP cyclohydrolase [Gloeocapsa sp. PCC 73106].	54.78	115	49	2	11	124	1	113	2e-35	132
rs:WP_008599642	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Propionibacterium].	58.95	95	39	0	18	112	19	113	2e-35	130
rs:WP_030012381	phosphoribosyl-AMP cyclohydrolase [Streptomyces lavendulae].	61.05	95	37	0	18	112	18	112	2e-35	130
rs:WP_031226393	phosphoribosyl-AMP cyclohydrolase [Streptomyces roseochromogenus].	62.11	95	36	0	18	112	21	115	2e-35	130
rs:WP_018297032	phosphoribosyl-AMP cyclohydrolase [Corynebacterium lubricantis].	62.11	95	36	0	18	112	18	112	2e-35	129
rs:WP_030707261	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-2580].	61.05	95	37	0	18	112	18	112	2e-35	130
tr:L8P801_STRVR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	62.11	95	36	0	18	112	20	114	2e-35	130
rs:WP_045864399	phosphoribosyl-AMP cyclohydrolase, partial [Streptomyces sp. WMMB 714].	55.36	112	49	1	2	112	1	112	2e-35	130
rs:WP_024814159	phosphoribosyl-AMP cyclohydrolase [Acidovorax sp. JHL-3].	48.74	119	57	1	16	130	5	123	2e-35	130
rs:WP_031107364	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-146].	57.55	106	43	1	18	121	16	121	2e-35	130
sp:HIS3_PROAC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	58.95	95	39	0	18	112	19	113	2e-35	130
sp:HIS3_CHLL2	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	54.90	102	46	0	17	118	14	115	2e-35	130
rs:WP_009718719	phosphoribosyl-AMP cyclohydrolase [Streptomyces himastatinicus].	61.05	95	37	0	18	112	18	112	2e-35	129
rs:WP_026243920	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	55.36	112	49	1	2	112	4	115	2e-35	130
tr:W4TE57_PROAA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	58.95	95	39	0	18	112	16	110	2e-35	129
rs:WP_045651674	phosphoribosyl-AMP cyclohydrolase [Gammaproteobacteria bacterium BRH_c0].	49.21	126	62	2	6	130	8	132	2e-35	130
rs:WP_016495145	phosphoribosyl-AMP cyclohydrolase [Pseudomonas resinovorans].	53.51	114	52	1	18	130	8	121	2e-35	130
rs:WP_003209300	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	53.51	114	52	1	18	130	8	121	2e-35	130
tr:A0A097IH22_9CORY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	61.05	95	37	0	18	112	16	110	2e-35	129
rs:WP_029144259	phosphoribosyl-AMP cyclohydrolase [Microbacterium luticocti].	61.05	95	37	0	18	112	12	106	2e-35	129
rs:WP_044975827	phosphoribosyl-AMP cyclohydrolase [[Eubacterium] cellulosolvens].	60.42	96	38	0	18	113	11	106	2e-35	129
tr:V6JVA4_STRRC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	62.11	95	36	0	18	112	37	131	2e-35	130
rs:WP_010106859	phosphoribosyl-AMP cyclohydrolase [Burkholderia oklahomensis].	53.98	113	48	2	18	126	14	126	2e-35	130
rs:WP_043500000	phosphoribosyl-AMP cyclohydrolase [Streptomyces glaucescens].	62.11	95	36	0	18	112	21	115	2e-35	130
rs:WP_043566047	phosphoribosyl-AMP cyclohydrolase [Acidovorax sp. KKS102].	48.74	119	57	1	16	130	5	123	2e-35	130
tr:K0HV17_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	49.15	118	56	1	18	131	25	142	2e-35	130
rs:WP_044577009	phosphoribosyl-AMP cyclohydrolase [Streptomyces iranensis].	62.11	95	36	0	18	112	18	112	2e-35	130
rs:WP_037889658	phosphoribosyl-AMP cyclohydrolase [Streptomyces viridochromogenes].	62.11	95	36	0	18	112	23	117	2e-35	130
rs:WP_030582126	phosphoribosyl-AMP cyclohydrolase [Streptomyces sclerotialus].	62.11	95	36	0	18	112	21	115	2e-35	130
rs:WP_006559819	phosphoribosyl-AMP cyclohydrolase [Acetobacter tropicalis].	52.00	125	59	1	1	124	1	125	2e-35	130
rs:WP_006826876	phosphoribosyl-AMP cyclohydrolase [Natrialba taiwanensis].	57.00	100	43	0	18	117	9	108	2e-35	130
rs:WP_006665193	phosphoribosyl-AMP cyclohydrolase [Natrialba aegyptia].	57.00	100	43	0	18	117	9	108	2e-35	130
tr:S2X0E3_DELAC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	49.57	117	55	1	18	130	10	126	2e-35	130
rs:WP_021698857	phosphoribosyl-AMP cyclohydrolase [Pseudomonas alcaligenes].	55.26	114	50	1	18	130	8	121	2e-35	130
sp:HIS3_DELAS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	49.57	117	55	1	18	130	10	126	2e-35	130
rs:WP_004065947	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Haloferax].	56.31	103	45	0	15	117	2	104	2e-35	129
rs:WP_039401082	phosphoribosyl-AMP cyclohydrolase [haloarchaeon 3A1_DGR].	57.00	100	43	0	18	117	3	102	2e-35	129
rs:WP_037884743	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-646].	52.89	121	54	2	2	119	4	124	2e-35	130
rs:WP_037836874	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	59.05	105	41	1	18	120	38	142	2e-35	130
rs:WP_030772182	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-2664].	61.05	95	37	0	18	112	18	112	2e-35	129
rs:WP_021207305	phosphoribosyl-AMP cyclohydrolase [Pseudomonas stutzeri].	52.63	114	53	1	18	130	7	120	2e-35	130
rs:WP_033273040	phosphoribosyl-AMP cyclohydrolase [Actinospica acidiphila].	55.36	112	49	1	2	112	1	112	2e-35	130
rs:WP_009543167	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Cyanothece].	56.86	102	43	1	18	118	19	120	2e-35	132
rs:WP_034399641	phosphoribosyl-AMP cyclohydrolase [Delftia acidovorans].	49.57	117	55	1	18	130	7	123	2e-35	130
rs:WP_034347626	phosphoribosyl-AMP cyclohydrolase [Delftia acidovorans].	49.57	117	55	1	18	130	7	123	2e-35	130
rs:WP_046163544	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. 10B238].	53.51	114	52	1	18	130	7	120	2e-35	130
rs:WP_017430366	hypothetical protein [Halomonas jeotgali].	63.83	94	34	0	20	113	37	130	2e-35	130
rs:WP_037728338	phosphoribosyl-AMP cyclohydrolase [Streptomyces scabiei].	62.11	95	36	0	18	112	9	103	2e-35	130
tr:K8E0T6_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	56.56	122	51	2	11	130	1	122	2e-35	132
rs:WP_008391331	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Clostridiales].	56.07	107	45	1	8	114	9	113	2e-35	129
rs:WP_018233370	phosphoribosyl-AMP cyclohydrolase [Thioalkalivibrio thiocyanodenitrificans].	51.30	115	55	1	17	130	8	122	2e-35	130
rs:WP_038090150	phosphoribosyl-AMP cyclohydrolase [Thiobacillus prosperus].	55.34	103	45	1	18	119	15	117	2e-35	130
rs:WP_004254025	phosphoribosyl-AMP cyclohydrolase [Thauera sp. 63].	49.57	117	57	2	16	130	9	125	2e-35	130
rs:WP_004932437	phosphoribosyl-AMP cyclohydrolase [Streptomyces griseoflavus].	62.11	95	36	0	18	112	21	115	2e-35	130
rs:WP_023092709	phosphoribosyl-AMP cyclohydrolase [Pseudomonas aeruginosa].	54.39	114	51	1	18	130	8	121	2e-35	130
rs:WP_005992590	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio fructosivorans].	61.39	101	38	1	23	122	10	110	2e-35	129
rs:WP_013974544	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	53.51	114	52	1	18	130	8	121	2e-35	130
rs:WP_012889635	phosphoribosyl-AMP cyclohydrolase [Streptosporangium roseum].	62.11	95	36	0	18	112	11	105	2e-35	129
rs:WP_014356601	phosphoribosyl-ATP pyrophosphatase [Acetobacterium woodii].	56.00	100	44	0	14	113	2	101	2e-35	132
rs:WP_030186017	phosphoribosyl-AMP cyclohydrolase, partial [Streptomyces violaceorubidus].	61.62	99	38	0	18	116	25	123	2e-35	129
tr:H5S869_9BACT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.85	123	51	2	9	130	2	118	2e-35	129
rs:WP_032503447	phosphoribosyl-AMP cyclohydrolase [Propionibacterium acnes].	58.95	95	39	0	18	112	19	113	2e-35	129
tr:W4U197_PROAA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	58.95	95	39	0	18	112	26	120	2e-35	130
rs:WP_046423122	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. MUSC136T].	58.04	112	40	2	18	122	21	132	2e-35	130
rs:WP_030031522	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	61.05	95	37	0	18	112	18	112	2e-35	129
tr:C9YVG9_STRSW	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	59.05	105	42	1	9	112	23	127	2e-35	130
rs:WP_004974115	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Haloferax].	56.31	103	45	0	15	117	2	104	2e-35	129
rs:WP_015661114	phosphoribosyl-AMP cyclohydrolase [Streptomyces davawensis].	53.85	117	53	1	1	116	1	117	2e-35	129
rs:WP_033256696	phosphoribosyl-AMP cyclohydrolase [Kitasatospora phosalacinea].	61.05	95	37	0	18	112	21	115	2e-35	129
rs:WP_022506313	phosphoribosyl-AMP cyclohydrolase [Eubacterium sp. CAG:581].	60.64	94	37	0	20	113	9	102	2e-35	129
rs:WP_031362186	phosphoribosyl-AMP cyclohydrolase [Burkholderia sordidicola].	50.82	122	55	2	1	121	1	118	2e-35	130
rs:WP_047350039	phosphoribosyl-AMP cyclohydrolase [Diaphorobacter sp. J5-51].	49.15	118	56	1	18	131	7	124	2e-35	129
rs:WP_043377190	phosphoribosyl-AMP cyclohydrolase [Streptomyces mutabilis].	62.11	95	36	0	18	112	20	114	2e-35	130
rs:WP_023635949	phosphoribosyl-AMP cyclohydrolase [Corynebacterium ulcerans].	58.18	110	42	2	6	112	4	112	2e-35	129
rs:WP_002521627	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Propionibacterium].	58.95	95	39	0	18	112	19	113	2e-35	129
rs:WP_013028768	phosphoribosyl-AMP cyclohydrolase [Sideroxydans lithotrophicus].	53.33	105	48	1	16	119	7	111	2e-35	129
rs:WP_011431829	phosphoribosyl-ATP pyrophosphatase [Synechococcus sp. JA-2-3B'a(2-13)].	61.22	98	37	1	17	113	6	103	2e-35	132
tr:D1YCC4_PROAA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	58.95	95	39	0	18	112	16	110	2e-35	129
rs:WP_007226575	phosphoribosyl-AMP cyclohydrolase [marine gamma proteobacterium HTCC2143].	62.50	96	36	0	18	113	27	122	2e-35	130
rs:WP_042414259	phosphoribosyl-AMP cyclohydrolase [Comamonas aquatica].	54.72	106	44	1	18	119	7	112	2e-35	129
rs:WP_038573393	phosphoribosyl-AMP cyclohydrolase [Corynebacterium doosanense].	61.05	95	37	0	18	112	21	115	2e-35	129
tr:B1WYF2_CYAA5	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	56.86	102	43	1	18	118	24	125	2e-35	132
sp:HIS3_PSEA7	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.51	114	52	1	18	130	8	121	2e-35	130
rs:WP_014322628	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio desulfuricans].	61.86	97	36	1	24	119	11	107	2e-35	129
rs:WP_016352478	phosphoribosyl-ATP diphosphatase [Spiribacter salinus].	58.65	104	42	1	18	121	7	109	2e-35	129
rs:WP_046261889	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. WM6386].	62.11	95	36	0	18	112	21	115	2e-35	130
rs:WP_028811499	phosphoribosyl-AMP cyclohydrolase [Streptomyces flavidovirens].	61.05	95	37	0	18	112	18	112	2e-35	129
rs:WP_005798813	phosphoribosyl-AMP cyclohydrolase [Acidovorax delafieldii].	49.58	119	56	1	16	130	5	123	2e-35	129
rs:WP_043560058	phosphoribosyl-AMP cyclohydrolase [Saccharibacter sp. AM169].	54.78	115	50	2	18	131	18	131	2e-35	130
tr:A0A085VBL2_PSESX	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	53.51	114	52	1	18	130	8	121	2e-35	129
rs:WP_025854425	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. CHM02].	59.41	101	41	0	17	117	25	125	2e-35	130
rs:WP_026929623	phosphoribosyl-AMP cyclohydrolase [Glycomyces tenuis].	60.00	95	38	0	18	112	4	98	2e-35	129
rs:WP_017292946	phosphoribosyl-AMP cyclohydrolase [Geminocystis herdmanii].	60.00	100	39	1	18	116	15	114	3e-35	129
rs:WP_037653160	phosphoribosyl-AMP cyclohydrolase [Streptomyces griseofuscus].	62.11	95	36	0	18	112	21	115	3e-35	129
rs:WP_047253393	phosphoribosyl-AMP cyclohydrolase [Corynebacterium testudinoris].	62.11	95	36	0	18	112	16	110	3e-35	129
rs:WP_035915365	phosphoribosyl-AMP cyclohydrolase [Knoellia sinensis].	57.69	104	41	1	12	112	6	109	3e-35	129
rs:WP_043862161	phosphoribosyl-AMP cyclohydrolase [Pseudomonas putida].	53.51	114	52	1	18	130	8	121	3e-35	129
rs:WP_037639062	phosphoribosyl-AMP cyclohydrolase [Streptomyces griseorubens].	62.11	95	36	0	18	112	18	112	3e-35	129
rs:WP_036991304	phosphoribosyl-AMP cyclohydrolase [Pseudomonas bauzanensis].	57.28	103	43	1	18	119	14	116	3e-35	130
tr:A0A089YWA5_STRGA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	62.11	95	36	0	18	112	32	126	3e-35	130
rs:WP_019046346	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Actinomycetales].	59.60	99	40	0	18	116	11	109	3e-35	129
rs:WP_044341965	phosphoribosyl-AMP cyclohydrolase [Pseudomonas oryzihabitans].	54.37	103	46	1	18	119	8	110	3e-35	129
rs:WP_042395728	phosphoribosyl-AMP cyclohydrolase [Streptacidiphilus carbonis].	61.05	95	37	0	18	112	21	115	3e-35	129
rs:WP_026924935	phosphoribosyl-AMP cyclohydrolase [Glycomyces arizonensis].	60.00	95	38	0	18	112	14	108	3e-35	129
rs:WP_008322370	phosphoribosyl-AMP cyclohydrolase [Haloferax elongans].	54.05	111	49	1	15	123	2	112	3e-35	129
rs:WP_006757061	phosphoribosyl-AMP cyclohydrolase [Burkholderia ambifaria].	47.62	126	62	2	5	126	2	127	3e-35	130
rs:WP_045248106	phosphoribosyl-AMP cyclohydrolase [Microbacterium ginsengisoli].	57.14	105	45	0	10	114	4	108	3e-35	129
rs:WP_015410156	phosphoribosyl-AMP cyclohydrolase [Natronomonas moolapensis].	54.39	114	50	1	18	131	5	116	3e-35	129
rs:WP_037802554	phosphoribosyl-AMP cyclohydrolase [Streptomyces resistomycificus].	54.39	114	49	1	2	112	1	114	3e-35	129
rs:WP_042736985	imidazole glycerol phosphate synthase [Lachnospiraceae bacterium TWA4].	59.60	99	40	0	16	114	11	109	3e-35	132
rs:WP_017307279	phosphoribosyl-ATP pyrophosphatase [Spirulina subsalsa].	61.86	97	36	1	18	113	18	114	3e-35	132
rs:WP_038651845	imidazole glycerol phosphate synthase [Prochlorococcus sp. MIT 0801].	56.86	102	43	1	17	117	6	107	3e-35	132
rs:WP_003453231	phosphoribosyl-AMP cyclohydrolase [Pseudomonas pseudoalcaligenes].	53.51	114	52	1	18	130	8	121	3e-35	129
rs:WP_018508751	phosphoribosyl-AMP cyclohydrolase [Thiobacillus thioparus].	50.88	114	55	1	18	130	8	121	3e-35	129
rs:WP_019139634	phosphoribosyl-AMP cyclohydrolase [Herbaspirillum massiliense].	50.00	114	56	1	16	128	9	122	3e-35	129
rs:WP_007161607	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	54.37	103	46	1	18	119	8	110	3e-35	129
rs:WP_036253786	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase, partial [Mesorhizobium].	58.65	104	41	1	20	121	29	132	3e-35	129
rs:WP_007676829	phosphoribosyl-AMP cyclohydrolase [alpha proteobacterium BAL199].	56.25	112	47	2	19	128	23	134	3e-35	130
rs:WP_028262569	phosphoribosyl-AMP cyclohydrolase [BRC1 bacterium SCGC AAA252-M09].	57.28	103	44	0	11	113	1	103	3e-35	129
tr:A0A031I0X4_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	48.72	117	56	1	18	130	10	126	3e-35	129
rs:WP_035296707	phosphoribosyl-AMP cyclohydrolase, partial [Actinocatenispora sera].	61.05	95	37	0	18	112	14	108	3e-35	129
rs:WP_041115322	phosphoribosyl-AMP cyclohydrolase [Pseudomonas protegens].	53.51	114	52	1	18	130	8	121	3e-35	129
sp:HIS3_PSEE4	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.51	114	52	1	18	130	8	121	3e-35	129
rs:WP_017135757	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	56.25	112	48	1	17	127	25	136	3e-35	129
rs:WP_045555792	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. FxanaA7].	59.05	105	42	1	9	112	20	124	3e-35	130
rs:WP_003776868	phosphoribosyl-AMP cyclohydrolase [Neisseria macacae].	53.45	116	53	1	17	131	8	123	3e-35	129
rs:WP_033172367	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. URHA0041].	60.00	95	38	0	18	112	14	108	3e-35	129
rs:WP_028292247	phosphoribosyl-AMP cyclohydrolase [Oceanobacter kriegii].	54.81	104	46	1	17	119	7	110	3e-35	129
rs:WP_044389260	phosphoribosyl-AMP cyclohydrolase [Marinobacter excellens].	53.40	103	47	1	18	119	17	119	3e-35	129
rs:WP_020293516	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. CFII64].	53.51	114	52	1	18	130	8	121	3e-35	129
rs:WP_047000986	phosphoribosyl-AMP cyclohydrolase [Clostridium beijerinckii].	55.14	107	47	1	11	116	3	109	3e-35	129
rs:WP_024882517	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. CNH189].	62.11	95	36	0	18	112	35	129	3e-35	130
rs:WP_028495736	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Microbacterium].	59.79	97	39	0	16	112	10	106	3e-35	129
rs:WP_017360538	phosphoribosyl-AMP cyclohydrolase [Pseudomonas mendocina].	52.63	114	53	1	18	130	8	121	3e-35	129
rs:WP_021760172	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio gigas].	61.39	101	38	1	21	120	13	113	3e-35	129
tr:A0A0D9LCG5_9NEIS	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:KJJ13279.1};	52.42	124	55	2	12	131	3	126	3e-35	129
rs:WP_006366319	phosphoribosyl-AMP cyclohydrolase [Chlorobium ferrooxidans].	56.70	97	42	0	17	113	14	110	3e-35	129
rs:WP_029614270	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. ICMP 17674].	54.39	114	51	1	18	130	8	121	3e-35	129
rs:WP_005610013	imidazole glycerol phosphate synthase [Ruminococcus lactaris].	59.26	108	42	1	9	116	222	327	3e-35	136
rs:WP_003769029	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Neisseriaceae].	53.91	115	52	1	18	131	9	123	3e-35	129
rs:WP_020029017	hypothetical protein [gamma proteobacterium SCGC AAA076-F14].	47.86	117	60	1	15	130	4	120	3e-35	129
rs:WP_035493237	phosphoribosyl-AMP cyclohydrolase [Geitlerinema sp. PCC 7105].	60.40	101	39	1	17	116	20	120	3e-35	129
rs:WP_028357395	phosphoribosyl-AMP cyclohydrolase [Brackiella oedipodis].	50.88	114	55	1	18	130	7	120	3e-35	129
rs:WP_036916796	phosphoribosyl-AMP cyclohydrolase [Propionimicrobium sp. BV2F7].	60.61	99	39	0	16	114	9	107	3e-35	129
rs:WP_036917156	MULTISPECIES: imidazole glycerol phosphate synthase [Prochlorococcus].	58.16	98	40	1	17	113	11	108	3e-35	132
rs:WP_003171182	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	53.51	114	52	1	18	130	8	121	3e-35	129
rs:WP_042367068	phosphoribosyl-AMP cyclohydrolase [Streptacidiphilus neutrinimicus].	61.05	95	37	0	18	112	21	115	3e-35	129
rs:WP_008611559	phosphoribosyl-AMP cyclohydrolase [Haloferax sp. BAB2207].	56.31	103	45	0	15	117	2	104	3e-35	129
rs:WP_030485479	phosphoribosyl-AMP cyclohydrolase [Marmoricola aequoreus].	60.00	95	38	0	18	112	16	110	3e-35	129
rs:WP_034396979	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Delftia].	48.72	117	56	1	18	130	7	123	3e-35	129
gp:CP000542_694	phosphoribosyl-AMP cyclohydrolase [Verminephrobacter eiseniae EF01-2]	49.61	127	59	2	9	131	21	146	3e-35	130
rs:WP_046236796	phosphoribosyl-AMP cyclohydrolase [Pseudomonas syringae pv. coryli].	53.51	114	52	1	18	130	8	121	3e-35	129
rs:WP_030353552	phosphoribosyl-AMP cyclohydrolase [Streptomyces scopuliridis].	61.05	95	37	0	18	112	22	116	3e-35	129
rs:WP_045074870	phosphoribosyl-AMP cyclohydrolase [Neisseria sp. HMSC06F02].	53.91	115	52	1	18	131	9	123	3e-35	129
rs:WP_025561794	phosphoribosyl-AMP cyclohydrolase [delta proteobacterium JGI 0000059-K16].	60.78	102	39	1	23	123	10	111	3e-35	129
rs:WP_017933835	phosphoribosyl-AMP cyclohydrolase [Nocardioides sp. Iso805N].	58.95	95	39	0	18	112	11	105	3e-35	129
rs:WP_019340499	phosphoribosyl-AMP cyclohydrolase [Pseudomonas stutzeri].	53.51	114	52	1	18	130	7	120	3e-35	129
rs:WP_018078719	phosphoribosyl-AMP cyclohydrolase [Thiobacillus denitrificans].	54.55	110	46	2	17	122	7	116	3e-35	129
rs:WP_008572327	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Haloferax].	57.69	104	43	1	18	121	10	112	3e-35	129
rs:WP_014967895	phosphoribosyl-AMP cyclohydrolase [Gottschalkia acidurici].	56.31	103	44	1	11	113	1	102	3e-35	129
rs:WP_012584704	phosphoribosyl-AMP cyclohydrolase [Thauera sp. MZ1T].	55.56	99	43	1	16	113	9	107	3e-35	129
rs:WP_009771325	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Burkholderia].	56.44	101	43	1	18	117	12	112	3e-35	129
rs:WP_027592414	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	53.51	114	52	1	18	130	8	121	3e-35	129
tr:A0A0A6PMU3_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	53.04	115	45	2	19	124	24	138	3e-35	130
sp:HIS3_PSEPW	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.51	114	52	1	18	130	8	121	3e-35	129
rs:WP_036321309	phosphoribosyl-AMP cyclohydrolase [Microbispora sp. ATCC PTA-5024].	59.41	101	41	0	18	118	11	111	3e-35	129
rs:WP_025164185	phosphoribosyl-AMP cyclohydrolase [Pseudomonas taeanensis].	54.39	114	51	1	18	130	8	121	3e-35	129
rs:WP_015475166	phosphoribosyl-AMP cyclohydrolase [Pseudomonas denitrificans].	54.39	114	51	1	18	130	8	121	3e-35	129
rs:WP_009313163	phosphoribosyl-AMP cyclohydrolase [Neisseria sp. GT4A_CT1].	53.91	115	52	1	18	131	9	123	3e-35	129
rs:WP_035558177	phosphoribosyl-AMP cyclohydrolase [Halomonas sp. KO116].	57.14	112	48	0	20	131	37	148	3e-35	130
rs:WP_020024041	hypothetical protein [gamma proteobacterium SCGC AAA076-D02].	47.83	115	59	1	17	130	6	120	3e-35	129
rs:WP_026180416	phosphoribosyl-AMP cyclohydrolase [Hahella ganghwensis].	50.00	112	55	1	18	128	13	124	3e-35	129
rs:WP_007731838	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. BT03].	56.44	101	43	1	18	117	12	112	3e-35	129
tr:A0A0D6BTU5_9PSED	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:BAQ78310.1};	53.51	114	52	1	18	130	8	121	3e-35	129
rs:WP_019309075	phosphoribosyl-AMP cyclohydrolase [Kocuria rhizophila].	62.11	95	36	0	18	112	24	118	3e-35	129
rs:WP_046785011	phosphoribosyl-AMP cyclohydrolase [Pseudomonas putida].	53.51	114	52	1	18	130	8	121	3e-35	129
rs:WP_029296001	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens group].	52.63	114	53	1	18	130	8	121	3e-35	129
rs:WP_023378315	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	53.51	114	52	1	18	130	8	121	3e-35	129
rs:WP_037049899	phosphoribosyl-AMP cyclohydrolase [Pseudomonas oleovorans].	52.63	114	53	1	18	130	8	121	3e-35	129
rs:WP_035831428	imidazole glycerol phosphate synthase [Cyanobium sp. CACIAM 14].	61.32	106	37	2	16	120	9	111	3e-35	132
rs:WP_042553875	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fulva].	53.51	114	52	1	18	130	8	121	4e-35	129
rs:WP_025262313	phosphoribosyl-AMP cyclohydrolase [Pseudomonas cichorii].	52.63	114	53	1	18	130	8	121	4e-35	129
rs:WP_023952061	phosphoribosyl-AMP cyclohydrolase [Pelistega sp. HM-7].	56.44	101	43	1	18	117	8	108	4e-35	129
rs:WP_004307338	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Thauera].	55.56	99	43	1	16	113	9	107	4e-35	129
rs:WP_027311480	phosphoribosyl-AMP cyclohydrolase [Balneatrix alpica].	57.84	102	42	1	18	118	9	110	4e-35	129
rs:WP_046500891	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL B-24891].	61.05	95	37	0	18	112	21	115	4e-35	129
rs:WP_014854407	phosphoribosyl-AMP cyclohydrolase [Pseudomonas stutzeri].	51.75	114	54	1	18	130	7	120	4e-35	129
rs:WP_029553770	phosphoribosyl-AMP cyclohydrolase [Streptomyces somaliensis].	61.05	95	37	0	18	112	13	107	4e-35	129
rs:WP_014367287	phosphoribosyl-AMP cyclohydrolase [Corynebacterium pseudotuberculosis].	63.16	95	34	1	18	112	19	112	4e-35	129
rs:WP_043327446	imidazole glycerol phosphate synthase [Cyanobium gracile].	60.75	107	38	2	16	121	8	111	4e-35	132
rs:WP_009181901	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio sp. FW1012B].	59.41	101	40	1	23	122	10	110	4e-35	129
tr:E3B723_9MICO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	59.79	97	39	0	18	114	18	114	4e-35	130
rs:WP_038570976	phosphoribosyl-AMP cyclohydrolase [Dermacoccus nishinomiyaensis].	59.79	97	39	0	18	114	18	114	4e-35	130
rs:WP_026228359	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. JPY251].	53.10	113	51	2	6	117	2	113	4e-35	129
tr:L1KXT5_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	55.08	118	48	2	9	121	23	140	4e-35	129
rs:WP_002707555	phosphoribosyl-AMP cyclohydrolase [Thiothrix nivea].	51.69	118	56	1	10	126	19	136	4e-35	129
rs:WP_018290535	hypothetical protein [Verrucomicrobium sp. 3C].	53.40	103	47	1	19	120	16	118	4e-35	129
rs:WP_020414023	hypothetical protein [Microbulbifer variabilis].	50.88	114	55	1	18	130	14	127	4e-35	129
rs:WP_022853194	phosphoribosyl-AMP cyclohydrolase [Thermodesulfatator atlanticus].	59.18	98	39	1	23	119	10	107	4e-35	129
gpu:CP009518_44	Phosphoribosyl-AMP cyclohydrolase [Methanococcoides methylutens MM1]	53.33	105	49	0	13	117	2	106	4e-35	129
rs:WP_008918715	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. H160].	53.10	113	51	2	6	117	2	113	4e-35	129
rs:WP_036308993	phosphoribosyl-AMP cyclohydrolase [Microbacterium oleivorans].	57.28	103	44	0	10	112	4	106	4e-35	129
rs:WP_027598924	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. MOIL14HWK12:I2].	54.37	103	46	1	18	119	8	110	4e-35	129
rs:WP_027707041	phosphoribosyl-AMP cyclohydrolase [Zooshikella ganghwensis].	58.59	99	40	1	16	113	13	111	4e-35	129
rs:WP_004519653	phosphoribosyl-AMP cyclohydrolase [Neisseria subflava].	52.99	117	54	1	16	131	10	126	4e-35	129
sp:HIS3_COREF	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	62.11	95	36	0	18	112	25	119	4e-35	129
rs:WP_040160499	phosphoribosyl-AMP cyclohydrolase [bacterium SIT7].	60.20	98	39	0	15	112	12	109	4e-35	129
rs:WP_010640670	phosphoribosyl-AMP cyclohydrolase [Acidithiobacillus thiooxidans].	59.18	98	40	0	16	113	11	108	4e-35	132
sp:HIS3_STRAW	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.94	119	53	2	4	119	6	124	4e-35	129
rs:WP_022151980	hypothetical protein [Lachnospiraceae bacterium CAG:215].	61.22	98	38	0	16	113	227	324	4e-35	135
rs:WP_038714902	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. lig30].	52.21	113	50	2	18	126	13	125	4e-35	129
tr:B4XN97_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	47.62	126	62	2	5	126	2	127	4e-35	129
rs:WP_031031053	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	59.05	105	41	1	18	120	5	109	4e-35	129
rs:WP_037668091	phosphoribosyl-AMP cyclohydrolase [Streptomyces afghaniensis].	58.10	105	42	1	18	120	5	109	4e-35	129
rs:WP_012964812	phosphoribosyl-AMP cyclohydrolase [Ferroglobus placidus].	53.92	102	47	0	17	118	2	103	4e-35	128
rs:WP_028654377	phosphoribosyl-AMP cyclohydrolase [Nocardioides sp. J54].	61.05	95	37	0	18	112	12	106	4e-35	128
rs:WP_031673018	phosphoribosyl-AMP cyclohydrolase [Pseudomonas aeruginosa].	53.51	114	52	1	18	130	8	121	4e-35	129
tr:F7JIM7_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	61.22	98	38	0	16	113	227	324	4e-35	135
rs:WP_016319447	hypothetical protein [Firmicutes bacterium M10-2].	55.14	107	42	1	11	117	4	104	4e-35	128
rs:WP_025841128	phosphoribosyl-AMP cyclohydrolase [Asaia platycodi].	57.69	104	43	1	11	113	11	114	4e-35	129
rs:WP_020129889	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. 303MFCol5.2].	56.88	109	45	1	18	124	21	129	4e-35	129
rs:WP_045549099	phosphoribosyl-AMP cyclohydrolase [Nocardioides luteus].	58.95	95	39	0	18	112	13	107	4e-35	128
rs:WP_027335754	phosphoribosyl-AMP cyclohydrolase [Halomonas sp. HL-48].	59.41	101	41	0	18	118	35	135	4e-35	130
rs:WP_023073001	phosphoribosyl-amp cyclohydrolase [Leptolyngbya sp. Heron Island J].	60.00	100	39	1	15	113	13	112	4e-35	131
rs:WP_046645252	phosphoribosyl-AMP cyclohydrolase [Corynebacterium striatum].	63.16	95	34	1	18	112	17	110	4e-35	129
rs:WP_005062479	hypothetical protein [Acinetobacter beijerinckii].	52.63	114	52	1	2	113	10	123	4e-35	129
rs:WP_043913425	phosphoribosyl-AMP cyclohydrolase [Kitasatospora griseola].	61.05	95	37	0	18	112	21	115	4e-35	129
rs:WP_015828212	phosphoribosyl-AMP cyclohydrolase [Hirschia baltica].	52.10	119	56	1	1	118	9	127	4e-35	129
tr:K9PBS9_CYAGP	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	60.75	107	38	2	16	121	30	133	4e-35	132
rs:WP_040027553	phosphoribosyl-AMP cyclohydrolase, partial [Streptomyces sp. 150FB].	61.05	95	37	0	18	112	21	115	4e-35	129
tr:C9Y870_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	47.86	117	57	1	18	130	15	131	4e-35	129
rs:WP_020446566	phosphoribosyl-AMP cyclohydrolase [Salinarchaeum sp. Harcht-Bsk1].	56.73	104	45	0	14	117	12	115	4e-35	129
rs:WP_034763490	imidazole glycerol phosphate synthase [Chrysiogenes arsenatis].	53.77	106	48	1	15	119	5	110	4e-35	131
rs:WP_004372946	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	52.63	114	53	1	18	130	8	121	4e-35	129
sp:HIS3_POLSJ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.43	117	54	1	18	130	7	123	5e-35	129
rs:WP_024072934	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. TKP].	52.63	114	53	1	18	130	8	121	5e-35	129
sp:HIS3_PELLD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.43	115	56	1	17	130	14	128	5e-35	129
rs:WP_021055420	phosphoribosyl-AMP cyclohydrolase [Haloquadratum walsbyi].	50.00	124	60	2	1	124	21	142	5e-35	129
rs:WP_044460754	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. MRSN12121].	52.63	114	53	1	18	130	8	121	5e-35	129
rs:WP_022235144	phosphoribosyl-AMP cyclohydrolase [Eubacterium sp. CAG:202].	56.73	104	42	1	11	114	5	105	5e-35	128
rs:WP_029667853	phosphoribosyl-AMP cyclohydrolase [Calescamantes bacterium JGI 0000106-I17].	52.29	109	50	2	18	124	12	120	5e-35	129
rs:WP_003213487	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	53.39	118	53	1	2	117	8	125	5e-35	129
rs:WP_027848590	phosphoribosyl-AMP cyclohydrolase [Marinospirillum minutulum].	62.50	96	36	0	18	113	29	124	5e-35	129
rs:WP_008367635	phosphoribosyl-AMP cyclohydrolase [Halorubrum litoreum].	50.43	117	53	1	1	117	1	112	5e-35	129
rs:WP_021982859	phosphoribosyl-ATP diphosphatase [Eubacterium sp. CAG:603].	59.43	106	41	1	9	114	225	328	5e-35	135
rs:WP_010563181	phosphoribosyl-AMP cyclohydrolase [Pseudomonas extremaustralis].	52.63	114	53	1	18	130	8	121	5e-35	129
rs:WP_009106499	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio sp. U5L].	59.41	101	40	1	23	122	10	110	5e-35	129
rs:WP_041747580	phosphoribosyl-AMP cyclohydrolase [Corynebacterium argentoratense].	59.41	101	41	0	15	115	10	110	5e-35	128
rs:WP_028537326	phosphoribosyl-AMP cyclohydrolase [Paludibacterium yongneupense].	53.51	114	52	1	18	130	6	119	5e-35	129
tr:F3KBS8_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.63	114	53	1	18	130	9	122	5e-35	129
rs:WP_014088624	phosphoribosyl-AMP cyclohydrolase [Pseudogulbenkiania sp. NH8B].	52.63	114	53	1	18	130	7	120	5e-35	129
rs:WP_044954518	hypothetical protein [Lachnospiraceae bacterium 1_4_56FAA].	61.22	98	38	0	16	113	210	307	5e-35	135
rs:WP_043058331	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. UASWS1009].	63.16	95	35	0	18	112	21	115	5e-35	129
sp:HIS3_HALWD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	55.77	104	45	1	18	121	17	119	5e-35	129
rs:WP_013515966	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio aespoeensis].	62.00	100	37	1	24	122	11	110	5e-35	129
rs:WP_015335662	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio hydrothermalis].	62.89	97	35	1	24	119	11	107	5e-35	129
rs:WP_037369981	phosphoribosyl-AMP cyclohydrolase [Amycolatopsis orientalis].	57.66	111	42	1	15	120	8	118	5e-35	128
tr:T2JFR7_CROWT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	50.42	119	56	2	1	118	4	120	5e-35	131
rs:WP_029626193	imidazole glycerol phosphate synthase [Synechococcus sp. CB0205].	63.27	98	35	1	17	113	15	112	5e-35	131
rs:WP_041780842	phosphoribosyl-AMP cyclohydrolase, partial [Microcoleus sp. PCC 7113].	60.00	100	39	1	18	116	11	110	5e-35	128
rs:WP_017777226	phosphoribosyl-AMP cyclohydrolase [Burkholderia kururiensis].	50.40	125	54	3	6	126	10	130	5e-35	129
rs:WP_030100682	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. K24].	51.28	117	55	2	6	121	2	117	5e-35	129
rs:WP_018402673	phosphoribosyl-AMP cyclohydrolase [Marinobacter lipolyticus].	50.43	115	56	1	17	130	16	130	5e-35	129
rs:WP_031483421	phosphoribosyl-AMP cyclohydrolase [Streptomyces bicolor].	61.05	95	37	0	18	112	23	117	5e-35	129
rs:WP_025130276	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. PH1b].	53.51	114	52	1	18	130	8	121	5e-35	129
rs:WP_013713706	phosphoribosyl-AMP cyclohydrolase [Pseudomonas mendocina].	52.63	114	53	1	18	130	8	121	5e-35	129
rs:WP_038753773	phosphoribosyl-AMP cyclohydrolase [Burkholderia pseudomallei].	53.10	113	49	2	18	126	14	126	5e-35	129
rs:WP_019271432	phosphoribosyl-AMP cyclohydrolase [Neisseria sicca].	53.91	115	52	1	18	131	9	123	5e-35	129
rs:WP_007312138	phosphoribosyl-ATP pyrophosphatase [Crocosphaera watsonii].	50.42	119	56	2	1	118	4	120	5e-35	131
rs:WP_035875070	phosphoribosyl-AMP cyclohydrolase [Cryobacterium sp. MLB-32].	56.03	116	41	3	13	128	7	112	5e-35	128
rs:WP_020939439	phosphoribosyl-AMP cyclohydrolase [Streptomyces collinus].	59.22	103	40	1	18	118	21	123	5e-35	129
tr:C0E4T5_9CORY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	53.10	113	52	1	1	112	5	117	5e-35	128
rs:WP_025253146	phosphoribosyl-AMP cyclohydrolase [Corynebacterium vitaeruminis].	62.11	95	35	1	18	112	24	117	5e-35	128
rs:WP_042453384	phosphoribosyl-AMP cyclohydrolase [Streptacidiphilus jiangxiensis].	61.05	95	37	0	18	112	21	115	5e-35	128
rs:WP_007307077	phosphoribosyl-ATP pyrophosphatase [Crocosphaera watsonii].	50.42	119	56	2	1	118	4	120	5e-35	131
sp:HIS3_JANMA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.27	107	49	1	16	121	9	115	5e-35	129
rs:WP_039716938	phosphoribosyl-AMP cyclohydrolase [Scytonema millei].	61.00	100	38	1	18	116	17	116	6e-35	128
rs:WP_010797015	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	52.63	114	53	1	18	130	8	121	6e-35	129
rs:WP_034092675	phosphoribosyl-AMP cyclohydrolase [Streptacidiphilus albus].	60.00	95	38	0	18	112	18	112	6e-35	128
rs:WP_030848352	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-475].	61.05	95	37	0	18	112	38	132	6e-35	129
rs:WP_036160765	phosphoribosyl-AMP cyclohydrolase [Marinimicrobium sp. LS-A18].	50.00	114	56	1	18	130	18	131	6e-35	129
rs:WP_029471401	phosphoribosyl-AMP cyclohydrolase [Clostridiales bacterium VE202-06].	57.58	99	42	0	20	118	7	105	6e-35	128
rs:WP_034117325	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	52.63	114	53	1	18	130	8	121	6e-35	129
rs:WP_033701934	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. WCS358].	53.51	114	52	1	18	130	8	121	6e-35	129
rs:WP_038608246	phosphoribosyl-AMP cyclohydrolase, partial [Corynebacterium atypicum].	60.00	95	38	0	18	112	9	103	6e-35	128
rs:WP_030941445	phosphoribosyl-AMP cyclohydrolase [Streptomyces violaceoruber].	57.41	108	42	1	18	121	18	125	6e-35	129
tr:A0A087FD40_9PSED	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.63	114	53	1	18	130	8	121	6e-35	129
rs:WP_030680767	phosphoribosyl-AMP cyclohydrolase [Streptomyces cellulosae].	57.41	108	42	1	18	121	18	125	6e-35	129
rs:WP_027854276	phosphoribosyl-AMP cyclohydrolase [Marinobacterium litorale].	53.91	115	51	2	18	130	9	123	6e-35	129
rs:WP_002928556	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Thauera].	55.56	99	43	1	16	113	9	107	6e-35	129
rs:WP_015238863	phosphoribosyl-AMP cyclohydrolase [Candidatus Kinetoplastibacterium crithidii].	48.80	125	61	3	2	124	1	124	6e-35	129
rs:WP_007259536	phosphoribosyl-AMP cyclohydrolase [Natronolimnobius innermongolicus].	57.01	107	45	1	11	117	1	106	6e-35	128
rs:WP_015360101	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Ruminiclostridium].	58.76	97	40	0	17	113	5	101	6e-35	128
rs:WP_038120085	phosphoribosyl-AMP cyclohydrolase [Verrucomicrobia bacterium LP2A].	55.88	102	44	1	19	119	20	121	6e-35	129
rs:WP_034995692	phosphoribosyl-AMP cyclohydrolase [Corynebacterium matruchotii].	53.10	113	52	1	1	112	1	113	6e-35	128
tr:B4XNG0_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	47.62	126	62	2	5	126	2	127	6e-35	129
tr:A0A0B9AVN7_BRELN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.89	95	40	0	18	112	16	110	6e-35	128
rs:WP_009117551	phosphoribosyl-AMP cyclohydrolase [Neisseria wadsworthii].	54.31	116	52	1	17	131	8	123	6e-35	129
rs:WP_014872740	phosphoribosyl-AMP cyclohydrolase [Marinobacter sp. BSs20148].	50.43	115	56	1	17	130	16	130	6e-35	129
rs:WP_015724507	phosphoribosyl-AMP cyclohydrolase [Desulfobulbus propionicus].	60.82	97	37	1	24	119	12	108	6e-35	128
rs:WP_015775252	phosphoribosyl-AMP cyclohydrolase [Desulfomicrobium baculatum].	61.17	103	33	2	12	113	5	101	6e-35	128
rs:WP_013706535	phosphoribosyl-AMP cyclohydrolase [Desulfobacca acetoxidans].	61.22	98	37	1	24	120	10	107	6e-35	128
sp:HIS3_BURA4	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	47.62	126	62	2	5	126	2	127	6e-35	129
rs:WP_039823890	phosphoribosyl-AMP cyclohydrolase [Nocardia testacea].	60.61	99	39	0	18	116	13	111	6e-35	128
rs:WP_044884468	phosphoribosyl-AMP cyclohydrolase [Frankia sp. CpI1-S].	59.79	97	39	0	16	112	14	110	6e-35	129
rs:WP_004362054	phosphoribosyl-AMP cyclohydrolase [Thauera phenylacetica].	54.55	99	44	1	16	113	9	107	6e-35	128
tr:F2BBE9_9NEIS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	49.61	129	63	2	5	131	25	153	6e-35	129
rs:WP_029605794	phosphoribosyl-AMP cyclohydrolase [Kozakia baliensis].	50.38	133	59	3	4	129	5	137	6e-35	129
rs:WP_045532024	phosphoribosyl-AMP cyclohydrolase [Comamonadaceae bacterium A1].	53.51	114	47	2	17	124	7	120	6e-35	129
rs:WP_028367584	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. UYPR1.413].	56.44	101	43	1	18	117	13	113	6e-35	129
rs:WP_007348469	phosphoribosyl-AMP cyclohydrolase [Marinobacter sp. ELB17].	50.43	115	56	1	17	130	16	130	6e-35	129
sp:HIS3_MICLC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	57.69	104	44	0	9	112	4	107	6e-35	128
rs:WP_030596445	phosphoribosyl-AMP cyclohydrolase [Streptomyces fulvoviolaceus].	54.46	112	50	1	2	112	1	112	7e-35	128
rs:WP_030228375	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL WC-3626].	54.46	112	50	1	2	112	4	115	7e-35	128
sp:HIS3_DESOH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	55.45	110	47	2	23	130	10	119	7e-35	128
tr:A0A0B5ETR9_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	58.95	95	39	0	18	112	21	115	7e-35	128
rs:WP_025133629	phosphoribosyl-AMP cyclohydrolase [Leucobacter sp. PH1c].	55.86	111	49	0	2	112	1	111	7e-35	128
rs:WP_033516935	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium scardovii].	53.91	115	44	1	7	112	2	116	7e-35	129
rs:WP_037955637	phosphoribosyl-AMP cyclohydrolase [Streptomyces sulphureus].	62.11	95	36	0	18	112	19	113	7e-35	128
rs:WP_016415155	phosphoribosyl-AMP cyclohydrolase [Halomonas anticariensis].	59.00	100	41	0	18	117	26	125	7e-35	129
sp:HIS3_FRAAA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	59.79	97	39	0	16	112	14	110	7e-35	128
rs:WP_037609288	phosphoribosyl-AMP cyclohydrolase [Streptacidiphilus rugosus].	61.05	95	37	0	18	112	15	109	7e-35	128
rs:WP_044178946	phosphoribosyl-AMP cyclohydrolase [Enterobacter massiliensis].	50.42	119	57	1	1	117	4	122	7e-35	128
rs:WP_030509961	phosphoribosyl-AMP cyclohydrolase [Microbispora rosea].	59.41	101	41	0	18	118	11	111	7e-35	128
rs:WP_042082660	phosphoribosyl-AMP cyclohydrolase [alpha proteobacterium Q-1].	57.69	104	43	1	19	121	28	131	7e-35	129
rs:WP_027602899	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	54.37	103	46	1	18	119	8	110	7e-35	128
tr:A0A0D6WU21_9ACTO	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:KIX78989.1};	60.00	95	38	0	18	112	18	112	7e-35	128
rs:WP_026780886	phosphoribosyl-AMP cyclohydrolase [Polaromonas sp. EUR3 1.2.1].	49.58	119	56	1	16	130	5	123	7e-35	128
tr:G9E8E3_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.90	102	46	0	17	118	20	121	7e-35	128
rs:WP_013457927	phosphoribosyl-ATP pyrophosphatase [Oceanithermus profundus].	54.72	106	46	1	11	116	1	104	7e-35	130
rs:WP_005526173	phosphoribosyl-AMP cyclohydrolase [Corynebacterium matruchotii].	53.10	113	52	1	1	112	1	113	7e-35	128
rs:WP_033379727	phosphoribosyl-AMP cyclohydrolase [Burkholderia bryophila].	55.24	105	46	1	18	121	12	116	7e-35	128
rs:WP_024645018	phosphoribosyl-AMP cyclohydrolase [Pseudomonas syringae].	52.63	114	53	1	18	130	8	121	7e-35	128
tr:U3GYL6_9CORY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	59.41	101	41	0	15	115	26	126	7e-35	128
rs:WP_016530997	hypothetical protein [Klebsiella pneumoniae].	50.42	119	57	1	1	117	4	122	7e-35	128
rs:WP_004851035	imidazole glycerol phosphate synthase [Coprococcus eutactus].	57.55	106	43	1	9	114	218	321	7e-35	135
rs:WP_022059013	phosphoribosyl-ATP diphosphatase [Coprococcus eutactus CAG:665].	57.55	106	43	1	9	114	218	321	7e-35	135
rs:WP_039207746	phosphoribosyl-AMP cyclohydrolase [Brevibacterium linens].	57.89	95	40	0	18	112	12	106	7e-35	128
rs:WP_012583489	phosphoribosyl-ATP pyrophosphatase [Dictyoglomus turgidum].	54.72	106	48	0	18	123	15	120	7e-35	130
rs:WP_029151920	phosphoribosyl-AMP cyclohydrolase [Microbacterium gubbeenense].	54.21	107	44	1	16	122	11	112	8e-35	128
rs:WP_018595502	phosphoribosyl-AMP cyclohydrolase [Blautia producta].	57.58	99	42	0	20	118	7	105	8e-35	127
rs:WP_044665394	phosphoribosyl-ATP pyrophosphatase [Syntrophaceticus schinkii].	50.82	122	54	2	11	127	14	134	8e-35	131
rs:WP_028431296	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. TAA204].	53.57	112	51	1	2	112	1	112	8e-35	128
tr:N6Z475_9RHOO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.55	99	44	1	16	113	7	105	8e-35	128
tr:Q13TR1_BURXL	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.29	105	47	1	18	121	13	117	8e-35	128
rs:WP_036960471	phosphoribosyl-AMP cyclohydrolase, partial [Pseudoclavibacter soli].	62.37	93	35	0	20	112	7	99	8e-35	127
rs:WP_042536640	phosphoribosyl-AMP cyclohydrolase [Microbacterium sp. MEJ108Y].	58.76	97	40	0	18	114	11	107	8e-35	128
rs:WP_042437661	phosphoribosyl-AMP cyclohydrolase [Streptacidiphilus albus].	60.00	95	38	0	18	112	24	118	8e-35	128
rs:WP_040254463	phosphoribosyl-AMP cyclohydrolase [Streptomyces albus].	58.95	95	39	0	18	112	18	112	8e-35	128
rs:WP_043448342	phosphoribosyl-AMP cyclohydrolase [Streptomyces nodosus].	61.05	95	37	0	18	112	21	115	8e-35	129
rs:WP_020027606	phosphoribosyl-AMP cyclohydrolase [gamma proteobacterium SCGC AAA076-E13].	47.83	115	59	1	17	130	6	120	8e-35	128
rs:WP_014800621	phosphoribosyl-AMP cyclohydrolase [Corynebacterium pseudotuberculosis].	63.16	95	34	1	18	112	19	112	8e-35	128
tr:K9GR33_9PROT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	63.16	95	35	0	19	113	27	121	8e-35	129
rs:WP_028792207	phosphoribosyl-AMP cyclohydrolase [Thauera linaloolentis].	54.55	99	44	1	16	113	9	107	8e-35	128
rs:WP_014130922	phosphoribosyl-AMP cyclohydrolase [Pelagibacterium halotolerans].	53.66	123	50	3	9	124	11	133	8e-35	129
rs:WP_020488831	hypothetical protein [Dehalobacter sp. FTH1].	58.95	95	39	0	18	112	12	106	8e-35	128
rs:WP_020947902	hypothetical protein [Klebsiella pneumoniae].	50.42	119	57	1	1	117	6	124	8e-35	128
tr:M3FT33_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	58.10	105	43	1	9	112	23	127	8e-35	129
rs:WP_004283878	phosphoribosyl-AMP cyclohydrolase [Neisseria weaveri].	54.31	116	52	1	17	131	8	123	8e-35	128
rs:WP_004596773	phosphoribosyl-AMP cyclohydrolase [Halorubrum distributum].	50.43	117	53	1	1	117	1	112	8e-35	128
rs:WP_030883698	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL S-1868].	60.00	95	38	0	18	112	15	109	8e-35	128
rs:WP_032446734	phosphoribosyl-AMP cyclohydrolase [Klebsiella pneumoniae].	50.42	119	57	1	1	117	4	122	8e-35	128
rs:WP_026334732	phosphoribosyl-AMP cyclohydrolase [Oxalobacteraceae bacterium AB_14].	52.88	104	48	1	18	120	17	120	8e-35	129
rs:WP_040275768	phosphoribosyl-AMP cyclohydrolase, partial [Streptomonospora alba].	60.00	95	38	0	18	112	9	103	8e-35	127
rs:WP_008096127	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. GM84].	53.51	114	52	1	18	130	8	121	8e-35	128
tr:V0B2C9_KLEPN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	50.42	119	57	1	1	117	10	128	8e-35	128
rs:WP_002241253	phosphoribosyl-AMP cyclohydrolase [Neisseria meningitidis].	53.91	115	52	1	18	131	9	123	8e-35	128
rs:WP_038458506	phosphoribosyl-AMP cyclohydrolase [Burkholderia xenovorans].	54.29	105	47	1	18	121	12	116	8e-35	128
rs:WP_004989339	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	54.46	112	50	1	2	112	1	112	8e-35	128
rs:WP_015074800	phosphoribosyl-AMP cyclohydrolase [Gluconobacter oxydans].	61.17	103	39	1	11	113	11	112	8e-35	128
rs:WP_028199646	phosphoribosyl-AMP cyclohydrolase [Burkholderia fungorum].	51.67	120	52	3	6	120	2	120	8e-35	128
rs:WP_027629354	imidazole glycerol phosphate synthase [[Clostridium] cellobioparum].	53.40	103	48	0	17	119	7	109	8e-35	130
rs:WP_012920681	phosphoribosyl-AMP cyclohydrolase [Kribbella flavida].	61.05	95	37	0	18	112	6	100	9e-35	127
rs:WP_030887261	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-5053].	60.00	95	38	0	18	112	15	109	9e-35	128
rs:WP_019581839	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	53.51	114	52	1	18	130	8	121	9e-35	128
rs:WP_027192052	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio putealis].	61.76	102	37	2	23	122	10	111	9e-35	128
rs:WP_037899662	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase, partial [Streptomyces].	61.05	95	37	0	18	112	20	114	9e-35	128
rs:WP_040479265	phosphoribosyl-AMP cyclohydrolase [Halomonas boliviensis].	54.90	102	46	0	17	118	24	125	9e-35	128
sp:HIS3_PSE14	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.63	114	53	1	18	130	8	121	9e-35	128
sp:HIS3_VEREI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.85	118	54	1	18	131	7	124	9e-35	128
rs:WP_018420072	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. WSM4176].	56.44	101	43	1	18	117	12	112	9e-35	128
rs:WP_008576461	phosphoribosyl-AMP cyclohydrolase [Haloferax sp. ATCC BAA-644].	54.13	109	48	1	15	123	2	108	9e-35	128
rs:WP_043646009	phosphoribosyl-AMP cyclohydrolase [Caenispirillum salinarum].	63.16	95	35	0	19	113	23	117	9e-35	128
rs:WP_015134717	phosphoribosyl-AMP cyclohydrolase [Leptolyngbya sp. PCC 7376].	57.84	102	42	1	18	118	12	113	9e-35	130
rs:WP_003709732	phosphoribosyl-AMP cyclohydrolase [Neisseria lactamica].	53.45	116	53	1	17	131	8	123	9e-35	128
rs:WP_007543920	phosphoribosyl-AMP cyclohydrolase [Haloferax larsenii].	51.67	120	55	2	15	131	2	121	9e-35	128
rs:WP_010544966	phosphoribosyl-AMP cyclohydrolase [Sphingomonas elodea].	57.84	102	43	0	19	120	14	115	9e-35	128
tr:I2IFI5_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.43	101	42	1	18	117	13	113	9e-35	128
rs:WP_040161002	phosphoribosyl-AMP cyclohydrolase [Mobilicoccus sp. SIT2].	59.79	97	39	0	18	114	17	113	9e-35	128
rs:WP_029654778	phosphoribosyl-AMP cyclohydrolase [Marinobacter daepoensis].	55.34	103	45	1	18	119	17	119	1e-34	128
tr:W7WSH8_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	50.43	117	54	1	18	130	7	123	1e-34	128
rs:WP_035518480	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. Ch1-1].	57.43	101	42	1	18	117	12	112	1e-34	128
rs:WP_036024394	phosphoribosyl-AMP cyclohydrolase [Burkholderia dilworthii].	55.24	105	46	1	18	121	12	116	1e-34	128
sp:HIS3_ANAVT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	59.41	101	40	1	18	117	11	111	1e-34	127
rs:WP_007925882	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	52.63	114	53	1	18	130	8	121	1e-34	128
rs:WP_019825247	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. CF149].	51.75	114	54	1	18	130	8	121	1e-34	128
rs:WP_011154563	hypothetical protein [Klebsiella pneumoniae].	50.42	119	57	1	1	117	6	124	1e-34	128
rs:WP_003341415	phosphoribosyl-AMP cyclohydrolase [Pseudomonas syringae].	52.63	114	53	1	18	130	8	121	1e-34	128
rs:WP_028435671	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. TAA486].	60.00	95	38	0	18	112	18	112	1e-34	128
rs:WP_017600189	phosphoribosyl-AMP cyclohydrolase [Nocardiopsis lucentensis].	56.19	105	45	1	9	112	4	108	1e-34	127
rs:WP_037867460	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-5140].	57.55	106	43	1	18	121	20	125	1e-34	128
rs:WP_003432368	phosphoribosyl-AMP cyclohydrolase [Pseudomonas syringae].	52.63	114	53	1	18	130	8	121	1e-34	128
rs:WP_027176665	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio aminophilus].	61.86	97	36	1	24	119	11	107	1e-34	127
rs:WP_033528209	phosphoribosyl-AMP cyclohydrolase [Streptomyces galbus].	61.05	95	37	0	18	112	9	103	1e-34	128
rs:WP_024833083	imidazole glycerol phosphate synthase [[Clostridium] josui].	45.45	121	60	1	16	130	6	126	1e-34	130
rs:WP_037822186	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-4835].	61.05	95	37	0	18	112	20	114	1e-34	128
rs:WP_013911825	phosphoribosyl-AMP cyclohydrolase [Corynebacterium ulcerans].	63.16	95	34	1	18	112	19	112	1e-34	127
rs:WP_006171117	phosphoribosyl-ATP pyrophosphatase [Synechococcus sp. WH 5701].	63.27	98	35	1	18	114	4	101	1e-34	130
tr:Q2Y4F9_9ARCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	53.33	105	49	0	13	117	5	109	1e-34	127
rs:WP_042662039	phosphoribosyl-AMP cyclohydrolase [Haloferax sp. ATB1].	57.69	104	43	1	18	121	10	112	1e-34	127
rs:WP_041656796	phosphoribosyl-AMP cyclohydrolase [Azoarcus sp. KH32C].	49.57	117	57	2	16	130	10	126	1e-34	128
tr:A0A0D0S4C2_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	59.60	99	40	0	16	114	108	206	1e-34	133
rs:WP_033293444	phosphoribosyl-AMP cyclohydrolase [Amycolatopsis jejuensis].	54.95	111	45	1	15	125	8	113	1e-34	127
rs:WP_018580561	phosphoribosyl-AMP cyclohydrolase [Corynebacterium pilosum].	62.11	95	36	0	18	112	18	112	1e-34	127
rs:WP_030417894	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-5065].	61.05	95	37	0	18	112	20	114	1e-34	128
rs:WP_022025188	phosphoribosyl-ATP diphosphatase [Clostridium sp. CAG:75].	58.00	100	42	0	14	113	217	316	1e-34	134
rs:WP_009271283	phosphoribosyl-AMP cyclohydrolase [Erysipelotrichaceae bacterium 3_1_53].	59.57	94	38	0	24	117	11	104	1e-34	127
rs:WP_008583984	phosphoribosyl-AMP cyclohydrolase [Halorubrum hochstenium].	48.80	125	57	2	1	123	1	120	1e-34	128
tr:K9WF01_9CYAN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	60.00	100	39	1	18	116	11	110	1e-34	128
tr:A0A0C2MCQ4_9CYAN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	61.00	100	38	1	18	116	11	110	1e-34	127
rs:WP_038024019	imidazole glycerol phosphate synthase [Synechococcus sp. RS9916].	62.89	97	35	1	18	113	12	108	1e-34	130
tr:H0PXA8_9RHOO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	49.57	117	57	2	16	130	11	127	1e-34	128
rs:WP_008578606	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Haloferax].	54.13	109	48	1	15	123	6	112	1e-34	127
rs:WP_020299480	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. CF161].	52.63	114	53	1	18	130	8	121	1e-34	128
rs:WP_004618742	phosphoribosyl-AMP cyclohydrolase [Caulobacter vibrioides].	52.63	114	52	1	19	130	24	137	1e-34	128
rs:WP_013980339	phosphoribosyl-AMP cyclohydrolase [Eggerthella sp. YY7918].	57.84	102	43	0	18	119	7	108	1e-34	127
rs:WP_003414224	phosphoribosyl-AMP cyclohydrolase [Pseudomonas syringae].	52.63	114	53	1	18	130	8	121	1e-34	128
tr:A0A094Q182_9ZZZZ	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGA15799.1};	58.33	96	40	0	17	112	9	104	1e-34	127
tr:R5I9Y0_9FIRM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	56.57	99	43	0	16	114	11	109	1e-34	127
rs:WP_027788536	phosphoribosyl-AMP cyclohydrolase [Burkholderia cepacia].	50.00	114	56	1	5	117	2	115	1e-34	128
rs:WP_004212825	phosphoribosyl-AMP cyclohydrolase [Klebsiella pneumoniae].	50.42	119	57	1	1	117	4	122	1e-34	128
rs:WP_043191394	phosphoribosyl-AMP cyclohydrolase [Pseudomonas rhizosphaerae].	52.63	114	53	1	18	130	8	121	1e-34	128
rs:WP_025777809	phosphoribosyl-AMP cyclohydrolase [Brevibacterium sp. VCM10].	58.95	95	39	0	18	112	16	110	1e-34	127
rs:WP_018989096	phosphoribosyl-AMP cyclohydrolase [Azoarcus toluclasticus].	56.57	99	42	1	16	113	11	109	1e-34	128
rs:WP_029544031	phosphoribosyl-ATP pyrophosphatase [Selenomonas ruminantium].	56.31	103	44	1	10	112	4	105	1e-34	131
rs:WP_015886619	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	56.44	101	44	0	17	117	25	125	1e-34	128
rs:WP_015325705	phosphoribosyl-AMP cyclohydrolase [Methanomethylovorans hollandica].	55.24	105	46	1	13	117	2	105	1e-34	127
rs:WP_027720625	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio zosterae].	61.86	97	36	1	24	119	11	107	1e-34	127
rs:WP_020627973	phosphoribosyl-AMP cyclohydrolase [Pseudonocardia sp. P2].	57.69	104	44	0	9	112	4	107	1e-34	127
rs:WP_042730518	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	52.63	114	53	1	18	130	8	121	1e-34	128
rs:WP_002222828	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Neisseria].	53.45	116	53	1	17	131	8	123	1e-34	127
tr:A0A0D6N590_9PROT	SubName: Full=Phosphoribosyl AMP cyclohydrolase {ECO:0000313|EMBL:GAN60681.1};	54.63	108	48	1	18	124	18	125	1e-34	128
rs:WP_012938297	phosphoribosyl-ATP pyrophosphatase [Acidaminococcus fermentans].	52.14	117	56	0	11	127	1	117	1e-34	130
rs:WP_046461075	phosphoribosyl-AMP cyclohydrolase [Comamonas testosteroni].	51.89	106	47	1	18	119	7	112	1e-34	127
rs:WP_022461872	phosphoribosyl-ATP pyrophosphohydrolase [Blautia sp. CAG:37].	55.14	107	47	1	12	117	8	114	1e-34	127
tr:A0A085E0W9_MICLU	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.69	104	44	0	9	112	4	107	1e-34	127
rs:WP_010213799	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	53.51	114	52	1	18	130	8	121	1e-34	127
rs:WP_036253406	phosphoribosyl-AMP cyclohydrolase [Massilia sp. BSC265].	47.41	116	60	1	16	130	9	124	1e-34	128
rs:WP_003058605	phosphoribosyl-AMP cyclohydrolase [Comamonas testosteroni].	51.89	106	47	1	18	119	7	112	1e-34	127
rs:WP_009074964	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. AA4].	55.36	112	46	1	15	122	8	119	1e-34	127
rs:WP_046729572	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. MUSC119T].	57.55	106	43	1	18	121	24	129	1e-34	128
sp:HIS3_CLOAB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	57.43	101	41	1	24	122	15	115	1e-34	127
rs:WP_034593564	phosphoribosyl-AMP cyclohydrolase, partial [Hamadaea tsunoensis].	59.79	97	39	0	18	114	28	124	1e-34	127
rs:WP_007701125	phosphoribosyl-AMP cyclohydrolase [Halovivax asiaticus].	57.00	100	43	0	18	117	6	105	1e-34	127
rs:WP_005089916	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Acinetobacter].	51.75	114	53	1	2	113	10	123	1e-34	128
rs:WP_037696259	phosphoribosyl-AMP cyclohydrolase [Streptomyces scabiei].	56.48	108	43	1	18	121	9	116	1e-34	127
rs:WP_044286511	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	53.51	114	52	1	18	130	8	121	1e-34	127
sp:HIS3_STRCO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	60.61	99	39	0	18	116	25	123	1e-34	127
rs:WP_017523117	hypothetical protein [Pusillimonas noertemannii].	58.10	105	42	2	18	121	14	117	1e-34	128
sp:HIS3_NITEU	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	48.70	115	58	1	17	130	8	122	1e-34	127
rs:WP_011878657	phosphoribosyl-ATP pyrophosphatase [Desulfotomaculum reducens].	58.88	107	43	1	11	116	1	107	1e-34	130
rs:WP_026411450	phosphoribosyl-AMP cyclohydrolase [Actinomadura oligospora].	57.84	102	43	0	18	119	18	119	1e-34	127
rs:WP_025343442	phosphoribosyl-ATP diphosphatase [Sulfurospirillum multivorans].	54.90	102	46	0	16	117	7	108	1e-34	130
rs:WP_045486456	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. StFLB209].	52.63	114	53	1	18	130	8	121	1e-34	127
rs:WP_004882689	phosphoribosyl-AMP cyclohydrolase [Pseudomonas viridiflava].	52.63	114	53	1	18	130	8	121	1e-34	127
rs:WP_010025870	phosphoribosyl-ATP pyrophosphatase [Sporolactobacillus inulinus].	51.33	113	55	0	13	125	1	113	1e-34	130
rs:WP_025824075	phosphoribosyl-AMP cyclohydrolase [Asaia astilbis].	60.20	98	38	1	17	113	17	114	1e-34	128
rs:WP_018440393	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. JPY347].	54.29	105	47	1	18	121	12	116	1e-34	127
rs:WP_024668727	phosphoribosyl-AMP cyclohydrolase [Pseudomonas syringae].	52.63	114	53	1	18	130	8	121	1e-34	127
rs:WP_043047255	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	52.63	114	53	1	18	130	8	121	1e-34	127
rs:WP_019691355	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	52.63	114	53	1	18	130	8	121	1e-34	127
rs:WP_036315375	phosphoribosyl-AMP cyclohydrolase [Micrococcus luteus].	57.69	104	44	0	9	112	4	107	2e-34	127
rs:WP_013661050	phosphoribosyl-AMP cyclohydrolase [Marinomonas mediterranea].	52.21	113	52	1	7	117	11	123	2e-34	127
rs:WP_027199016	phosphoribosyl-AMP cyclohydrolase [Burkholderia sprentiae].	53.10	113	51	2	6	117	2	113	2e-34	127
sp:HIS3_PELPB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	56.70	97	42	0	17	113	14	110	2e-34	127
rs:WP_042825984	phosphoribosyl-AMP cyclohydrolase, partial [Streptomyces coelicoflavus].	59.60	99	40	0	18	116	25	123	2e-34	127
sp:HIS2_SYNPX	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	62.89	97	35	1	18	113	12	108	2e-34	130
rs:WP_018916137	phosphoribosyl-AMP cyclohydrolase [Halomonas zhanjiangensis].	60.42	96	38	0	18	113	35	130	2e-34	128
rs:WP_046248154	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. MBT28].	61.05	95	37	0	18	112	20	114	2e-34	128
rs:WP_041108532	phosphoribosyl-AMP cyclohydrolase [Pseudomonas stutzeri].	51.75	114	54	1	18	130	7	120	2e-34	127
rs:WP_033939876	phosphoribosyl-AMP cyclohydrolase [Pseudomonas aeruginosa].	53.51	114	52	1	18	130	8	121	2e-34	127
rs:WP_041344108	phosphoribosyl-AMP cyclohydrolase [Marinobacter similis].	53.85	104	47	1	17	119	3	106	2e-34	127
rs:WP_002608157	phosphoribosyl-AMP cyclohydrolase [[Clostridium] innocuum].	58.51	94	39	0	24	117	11	104	2e-34	127
rs:WP_017830576	hypothetical protein [Microbacterium sp. UCD-TDU].	51.79	112	54	0	1	112	1	112	2e-34	127
rs:WP_041075783	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. OxB-1].	55.66	106	47	0	11	116	1	106	2e-34	130
rs:WP_041087318	phosphoribosyl-ATP pyrophosphatase [Jeotgalibacillus soli Cunha et al. 2012].	54.00	100	46	0	13	112	7	106	2e-34	130
rs:WP_010453595	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fuscovaginae].	56.86	102	43	1	18	118	8	109	2e-34	127
rs:WP_036190600	phosphoribosyl-AMP cyclohydrolase [Marinobacterium sp. AK27].	54.78	115	50	2	18	130	9	123	2e-34	127
rs:WP_020655439	phosphoribosyl-AMP cyclohydrolase [Massilia niastensis].	47.41	116	60	1	16	130	7	122	2e-34	127
rs:WP_008161661	phosphoribosyl-AMP cyclohydrolase [Natronorubrum sulfidifaciens].	54.81	104	47	0	14	117	3	106	2e-34	127
rs:WP_022194168	phosphoribosyl-AMP cyclohydrolase [Clostridium sp. CAG:217].	57.14	98	42	0	20	117	9	106	2e-34	127
rs:WP_017344175	phosphoribosyl-AMP cyclohydrolase [Halorubrum sp. T3].	49.57	117	54	1	1	117	1	112	2e-34	127
rs:WP_015415839	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio piezophilus].	60.82	97	37	1	24	119	11	107	2e-34	127
rs:WP_036981475	phosphoribosyl-AMP cyclohydrolase [Propionibacterium jensenii].	54.13	109	48	1	15	121	8	116	2e-34	127
rs:WP_003748650	phosphoribosyl-AMP cyclohydrolase [Neisseria mucosa].	52.14	117	55	1	16	131	10	126	2e-34	127
rs:WP_031482339	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio frigidus].	60.82	97	37	1	24	119	11	107	2e-34	127
rs:WP_047259834	phosphoribosyl-AMP cyclohydrolase [Corynebacterium uterequi].	61.05	95	37	0	18	112	18	112	2e-34	127
sp:HIS3_CHLT3	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	46.72	122	64	1	4	125	2	122	2e-34	127
rs:WP_045265321	phosphoribosyl-AMP cyclohydrolase [Microbacterium oxydans].	51.75	114	55	0	1	114	1	114	2e-34	127
rs:WP_022962012	phosphoribosyl-AMP cyclohydrolase [Pseudomonas pelagia].	59.60	99	40	0	18	116	25	123	2e-34	127
rs:WP_044826043	hypothetical protein [Clostridium aceticum].	58.00	100	42	0	17	116	6	105	2e-34	129
gpu:CP009505_2574	Phosphoribosyl-AMP cyclohydrolase [Methanosarcina sp. MTP4]	58.88	107	41	2	11	117	2	105	2e-34	127
rs:WP_039340299	phosphoribosyl-AMP cyclohydrolase [Mumia flava].	58.95	95	39	0	18	112	18	112	2e-34	127
rs:WP_046990967	phosphoribosyl-ATP diphosphatase [Arcobacter butzleri].	59.34	91	37	0	24	114	14	104	2e-34	130
rs:WP_020847192	phosphoribosyl-AMP cyclohydrolase [Arcobacter butzleri].	59.34	91	37	0	24	114	14	104	2e-34	130
rs:WP_015744780	phosphoribosyl-ATP pyrophosphatase [Candidatus Methylomirabilis oxyfera].	51.38	109	53	0	13	121	4	112	2e-34	130
rs:WP_028796907	phosphoribosyl-AMP cyclohydrolase [Streptomyces bottropensis].	61.05	95	37	0	18	112	9	103	2e-34	127
rs:WP_041956100	phosphoribosyl-ATP diphosphatase [Sulfurospirillum arsenophilum].	53.92	102	47	0	16	117	7	108	2e-34	130
rs:WP_029210462	phosphoribosyl-AMP cyclohydrolase [Arsenicicoccus bolidensis].	58.59	99	41	0	16	114	18	116	2e-34	127
rs:WP_012012020	phosphoribosyl-ATP pyrophosphatase [Arcobacter butzleri].	59.34	91	37	0	24	114	14	104	2e-34	130
rs:WP_046992687	phosphoribosyl-ATP diphosphatase [Arcobacter butzleri].	59.34	91	37	0	24	114	14	104	2e-34	130
rs:WP_046064118	phosphoribosyl-AMP cyclohydrolase [Pseudomonas kilonensis].	52.63	114	53	1	18	130	8	121	2e-34	127
rs:WP_022358084	phosphoribosyl-AMP cyclohydrolase [Ruminococcus sp. CAG:379].	58.76	97	40	0	20	116	7	103	2e-34	127
rs:WP_038487478	phosphoribosyl-AMP cyclohydrolase [Janthinobacterium agaricidamnosum].	52.43	103	48	1	16	117	9	111	2e-34	127
rs:WP_046070538	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	52.63	114	53	1	18	130	8	121	2e-34	127
rs:WP_020388800	phosphoribosyl-AMP cyclohydrolase [Kribbella catacumbae].	58.00	100	42	0	13	112	1	100	2e-34	127
rs:WP_028945559	phosphoribosyl-AMP cyclohydrolase [Pseudomonas vranovensis].	52.63	114	53	1	18	130	8	121	2e-34	127
rs:WP_017333605	phosphoribosyl-AMP cyclohydrolase [Burkholderia pyrrocinia].	49.57	117	58	1	6	121	3	119	2e-34	127
rs:WP_004510163	phosphoribosyl-ATP pyrophosphatase [Arcobacter butzleri].	59.34	91	37	0	24	114	14	104	2e-34	130
rs:WP_015558916	phosphoribosyl-AMP cyclohydrolase [Ruminococcus champanellensis].	58.76	97	40	0	20	116	7	103	2e-34	127
rs:WP_013506109	phosphoribosyl-ATP diphosphatase [Desulfurispirillum indicum].	58.25	103	42	1	18	119	6	108	2e-34	130
rs:WP_042120483	phosphoribosyl-AMP cyclohydrolase [Pseudomonas japonica].	52.63	114	53	1	18	130	8	121	2e-34	127
sp:HIS3_NEIMA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.59	116	54	1	17	131	8	123	2e-34	127
rs:WP_019528375	hypothetical protein [Dasania marina].	54.37	103	46	1	18	119	11	113	2e-34	127
rs:WP_026148852	phosphoribosyl-AMP cyclohydrolase [Leptolyngbya boryana].	59.00	100	40	1	18	116	11	110	2e-34	127
tr:D4J3A9_BUTFI	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	52.14	117	54	1	16	130	77	193	2e-34	131
rs:WP_004044895	phosphoribosyl-AMP cyclohydrolase [Haloferax volcanii].	55.34	103	46	0	15	117	2	104	2e-34	127
rs:WP_044406666	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. FeS53a].	51.75	114	54	1	18	130	8	121	2e-34	127
rs:WP_006786564	phosphoribosyl-AMP cyclohydrolase [Thiorhodospira sibirica].	56.31	103	44	1	18	119	10	112	2e-34	127
rs:WP_009304782	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Eggerthella].	57.00	100	43	0	14	113	2	101	2e-34	126
rs:WP_022888018	phosphoribosyl-AMP cyclohydrolase [Agromyces italicus].	61.29	93	36	0	20	112	16	108	2e-34	127
rs:WP_043182231	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. NRRL F-5123].	61.05	95	37	0	18	112	25	119	2e-34	127
rs:WP_038109774	phosphoribosyl-AMP cyclohydrolase, partial [Varibaculum cambriense].	57.55	106	41	1	16	121	12	113	2e-34	127
rs:WP_009174779	phosphoribosyl-AMP cyclohydrolase [Neisseria sp. oral taxon 014].	53.04	115	53	1	18	131	9	123	2e-34	127
rs:WP_030919408	phosphoribosyl-AMP cyclohydrolase [Streptosporangium amethystogenes].	58.95	95	39	0	18	112	11	105	2e-34	127
rs:WP_018382764	phosphoribosyl-AMP cyclohydrolase [Streptomyces vitaminophilus].	60.00	95	38	0	18	112	16	110	2e-34	127
rs:WP_028693524	phosphoribosyl-AMP cyclohydrolase [Pseudomonas cremoricolorata].	53.51	114	52	1	18	130	8	121	2e-34	127
sp:HIS3_PSESM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.63	114	53	1	18	130	8	121	2e-34	127
rs:WP_041961289	phosphoribosyl-AMP cyclohydrolase [Neisseria elongata].	51.69	118	55	2	16	131	7	124	2e-34	127
rs:WP_012402122	phosphoribosyl-AMP cyclohydrolase [Burkholderia phymatum].	55.45	101	44	1	18	117	12	112	2e-34	127
tr:W1VI43_9ACTO	SubName: Full=Imidazole glycerol phosphate synthase subunit hisF {ECO:0000313|EMBL:ETJ04495.1}; Flags: Fragment;	60.20	98	39	0	15	112	105	202	2e-34	130
rs:WP_009743014	phosphoribosyl-AMP cyclohydrolase [Frankia sp. QA3].	57.73	97	41	0	16	112	14	110	2e-34	127
rs:WP_030139118	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	52.17	115	53	1	18	130	8	122	2e-34	127
sp:HIS3_THIDA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	57.73	97	40	1	18	113	8	104	2e-34	127
rs:WP_037016072	phosphoribosyl-AMP cyclohydrolase [Pseudomonas lutea].	52.63	114	53	1	18	130	8	121	2e-34	127
rs:WP_024779928	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	52.63	114	53	1	18	130	8	121	2e-34	127
sp:HIS3_POLNA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	49.15	118	56	1	17	130	6	123	2e-34	127
rs:WP_016687645	phosphoribosyl-AMP cyclohydrolase [Neisseria sicca].	52.59	116	54	1	17	131	8	123	2e-34	127
rs:WP_047225987	phosphoribosyl-AMP cyclohydrolase [Pseudomonas brassicacearum].	52.63	114	53	1	18	130	8	121	2e-34	127
rs:WP_018024701	hypothetical protein [Corynebacterium ulceribovis].	58.95	95	39	0	18	112	22	116	2e-34	127
rs:WP_043675282	phosphoribosyl-AMP cyclohydrolase [Streptomyces xylophagus].	53.57	112	51	1	2	112	1	112	2e-34	127
rs:WP_002684607	phosphoribosyl-AMP cyclohydrolase [Beggiatoa alba].	53.40	103	47	1	18	119	11	113	2e-34	127
rs:WP_013272649	phosphoribosyl-ATP diphosphatase [[Clostridium] saccharolyticum].	63.54	96	35	0	18	113	231	326	2e-34	134
rs:WP_020097286	phosphoribosyl-AMP cyclohydrolase [Microbacterium sp. 11MF].	59.79	97	39	0	16	112	10	106	2e-34	127
rs:WP_046916389	phosphoribosyl-AMP cyclohydrolase [Streptomyces stelliscabiei].	61.05	95	37	0	18	112	10	104	2e-34	127
rs:WP_036513345	phosphoribosyl-AMP cyclohydrolase [Nitrincola sp. AK23].	51.79	112	53	1	16	126	7	118	2e-34	127
rs:WP_035642417	imidazole glycerol phosphate synthase [Lachnospiraceae bacterium FE2018].	54.72	106	47	1	18	122	1	106	2e-34	129
rs:WP_003458972	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	51.75	114	54	1	18	130	8	121	2e-34	127
rs:WP_004080678	phosphoribosyl-ATP diphosphatase [Clostridium sp. ASF502].	59.05	105	41	1	9	113	222	324	2e-34	134
rs:WP_006864364	imidazole glycerol phosphate synthase [Marvinbryantia formatexigens].	53.33	120	54	1	13	130	224	343	2e-34	134
rs:WP_007279982	phosphoribosyl-AMP cyclohydrolase [Lentisphaera araneosa].	51.35	111	53	1	21	130	14	124	2e-34	127
rs:WP_016395359	phosphoribosyl-AMP cyclohydrolase [Pseudomonas plecoglossicida].	52.63	114	53	1	18	130	8	121	2e-34	127
rs:WP_018718095	hypothetical protein [Arhodomonas aquaeolei].	56.25	112	48	1	20	130	9	120	2e-34	127
tr:A0A086GYX2_STRSC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.24	118	49	2	9	121	26	143	2e-34	127
rs:WP_025402544	phosphoribosyl-AMP cyclohydrolase [Corynebacterium falsenii].	62.11	95	36	0	18	112	19	113	2e-34	127
rs:WP_043218003	phosphoribosyl-AMP cyclohydrolase [Pseudomonas balearica].	51.75	114	54	1	18	130	7	120	2e-34	127
rs:WP_022870866	phosphoribosyl-AMP cyclohydrolase [Yaniella halotolerans].	58.49	106	42	1	18	121	21	126	2e-34	127
rs:WP_041631367	phosphoribosyl-AMP cyclohydrolase [Corynebacterium terpenotabidum].	55.79	95	42	0	18	112	9	103	2e-34	126
rs:WP_027283910	phosphoribosyl-AMP cyclohydrolase [Rubritepida flocculans].	57.73	97	41	0	17	113	22	118	2e-34	127
rs:WP_046104509	phosphoribosyl-AMP cyclohydrolase [Devosia chinhatensis].	55.96	109	44	2	19	123	25	133	2e-34	127
rs:WP_040667955	phosphoribosyl-AMP cyclohydrolase [Neisseria sicca].	52.59	116	54	1	17	131	8	123	2e-34	127
rs:WP_005888181	phosphoribosyl-AMP cyclohydrolase [Pseudomonas coronafaciens].	52.63	114	53	1	18	130	8	121	2e-34	127
tr:Q05RB9_9SYNE	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	62.89	97	35	1	18	113	36	132	2e-34	130
rs:WP_013322892	phosphoribosyl-ATP pyrophosphatase [Cyanothece sp. PCC 7822].	58.59	99	40	1	18	115	15	113	2e-34	129
sp:HIS3_ACIC1	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	61.05	95	37	0	18	112	16	110	2e-34	127
rs:WP_011244411	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Synechococcus].	55.96	109	47	1	10	117	5	113	2e-34	129
rs:WP_020814037	phosphoribosyl-ATP pyrophosphatase [[Clostridium] papyrosolvens].	45.45	121	60	1	16	130	6	126	2e-34	129
rs:WP_014256863	phosphoribosyl-ATP pyrophosphatase [[Clostridium] clariflavum].	55.34	103	45	1	18	119	8	110	2e-34	129
rs:WP_012375396	phosphoribosyl-AMP cyclohydrolase [Opitutus terrae].	59.18	98	37	1	19	113	24	121	2e-34	127
rs:WP_003378890	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas syringae group].	52.63	114	53	1	18	130	8	121	2e-34	127
rs:WP_024672475	phosphoribosyl-AMP cyclohydrolase [Pseudomonas syringae].	51.75	114	54	1	18	130	8	121	2e-34	127
rs:WP_018186767	phosphoribosyl-AMP cyclohydrolase [Microbacterium paraoxydans].	59.79	97	39	0	16	112	10	106	2e-34	127
rs:WP_010581816	phosphoribosyl-AMP cyclohydrolase [Schlesneria paludicola].	59.05	105	42	1	14	117	3	107	2e-34	127
rs:WP_035088934	phosphoribosyl-AMP cyclohydrolase [Devosia sp. 17-2-E-8].	55.05	109	45	2	19	123	25	133	2e-34	127
rs:WP_024516900	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. Tv2a-2].	53.21	109	49	1	19	125	20	128	2e-34	127
gp:CP006471_1200	imidazole glycerol phosphate synthase [Synechococcus sp. UTEX 2973]	55.96	109	47	1	10	117	8	116	2e-34	129
rs:WP_018124269	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio oxyclinae].	60.82	97	37	1	24	119	10	106	2e-34	127
rs:WP_029462357	phosphoribosyl-AMP cyclohydrolase [Comamonadaceae bacterium H1].	52.63	114	48	2	17	124	7	120	2e-34	127
tr:A0A094PPT6_9ACTN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	60.00	95	38	0	18	112	24	118	2e-34	127
rs:WP_034594542	hypothetical protein [Clostridiales bacterium VE202-14].	53.91	115	51	1	2	116	203	315	2e-34	134
rs:WP_036472643	phosphoribosyl-AMP cyclohydrolase [Neisseria flavescens].	52.14	117	55	1	16	131	10	126	2e-34	127
rs:XP_005538270	histidine biosynthesis bifunctional protein HisIE [Cyanidioschyzon merolae strain 10D].	54.46	112	50	1	18	128	78	189	2e-34	129
sp:HIS3_CELJU	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.25	111	51	2	17	126	7	116	2e-34	127
rs:WP_029553057	imidazole glycerol phosphate synthase [Synechococcus sp. CB0101].	62.24	98	36	1	17	113	15	112	2e-34	130
tr:I5AQM2_EUBCE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00006950}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	63.33	90	33	0	24	113	213	302	2e-34	132
rs:WP_039680829	phosphoribosyl-ATP pyrophosphatase [Terrisporobacter othiniensis].	51.30	115	52	2	2	116	1	111	2e-34	129
rs:WP_022501757	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [Eubacterium sp. CAG:76].	59.18	98	40	0	16	113	257	354	2e-34	133
rs:WP_033505574	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium thermacidophilum].	51.67	120	49	1	2	112	1	120	2e-34	127
rs:WP_019196438	phosphoribosyl-AMP cyclohydrolase [Afipia birgiae].	52.29	109	50	1	19	125	20	128	2e-34	127
rs:WP_038272152	phosphoribosyl-AMP cyclohydrolase [actinobacterium acAMD-2].	60.00	95	38	0	18	112	16	110	2e-34	127
rs:WP_035467239	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. WSM2232].	54.29	105	47	1	18	121	12	116	2e-34	127
rs:WP_039416019	phosphoribosyl-AMP cyclohydrolase [Microbacterium hominis].	58.95	95	39	0	18	112	12	106	2e-34	127
tr:E1TAS1_BURSG	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	54.29	105	47	1	18	121	13	117	2e-34	127
rs:WP_025601885	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. WSM2230].	54.29	105	47	1	18	121	13	117	2e-34	127
rs:WP_036233294	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Methylibium].	50.43	117	54	1	18	130	7	123	2e-34	127
rs:WP_041793641	phosphoribosyl-AMP cyclohydrolase [Rhodospirillum photometricum].	58.00	100	42	0	18	117	16	115	2e-34	127
rs:WP_015048216	phosphoribosyl-AMP cyclohydrolase [Simiduia agarivorans].	55.34	103	45	1	18	119	9	111	2e-34	127
rs:WP_003186669	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	52.63	114	53	1	18	130	8	121	3e-34	127
sp:HIS3_PSEU2	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.63	114	53	1	18	130	8	121	3e-34	127
gpu:CP009516_3327	Phosphoribosyl-AMP cyclohydrolase [Methanosarcina horonobensis HB-1]	57.94	107	42	2	11	117	2	105	3e-34	127
rs:WP_027014025	phosphoribosyl-AMP cyclohydrolase [Comamonas composti].	50.86	116	53	1	20	131	9	124	3e-34	127
rs:WP_036951034	phosphoribosyl-AMP cyclohydrolase [Promicromonosporaceae bacterium W15].	60.82	97	38	0	16	112	19	115	3e-34	127
tr:C6M261_NEISI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	51.61	124	56	2	12	131	3	126	3e-34	127
rs:WP_041729130	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. CCGE1003].	54.29	105	47	1	18	121	12	116	3e-34	127
rs:WP_031446755	phosphoribosyl-AMP cyclohydrolase [Caulobacteraceae bacterium PMMR1].	58.10	105	42	1	17	119	20	124	3e-34	127
gpu:CP011020_1201	phosphoribosyl-AMP cyclohydrolase [Pseudomonas chlororaphis]	52.63	114	53	1	18	130	8	121	3e-34	127
rs:WP_044499517	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. 12M76_air].	56.31	103	44	1	18	119	14	116	3e-34	127
tr:M5R932_9PLAN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	55.24	105	45	1	14	116	5	109	3e-34	127
rs:WP_004267554	phosphoribosyl-AMP cyclohydrolase [Natrialba magadii].	58.00	100	42	0	18	117	205	304	3e-34	132
rs:WP_028793691	phosphoribosyl-AMP cyclohydrolase [Thalassobaculum salexigens].	50.79	126	56	2	7	131	16	136	3e-34	127
rs:WP_005055238	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Microbacterium].	60.00	95	38	0	18	112	12	106	3e-34	127
tr:W1TP04_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.55	106	41	1	16	121	12	113	3e-34	127
rs:WP_003679441	phosphoribosyl-AMP cyclohydrolase [Neisseria flavescens].	52.14	117	55	1	16	131	10	126	3e-34	127
rs:WP_007001730	hypothetical protein [Actinobaculum massiliense].	60.00	95	38	0	18	112	19	113	3e-34	127
rs:WP_036289475	phosphoribosyl-AMP cyclohydrolase [Microbacterium sp. MRS-1].	58.95	95	39	0	18	112	12	106	3e-34	127
sp:HIS3_BURL3	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.00	114	56	1	5	117	2	115	3e-34	127
rs:WP_014741406	phosphoribosyl-AMP cyclohydrolase [Modestobacter marinus].	57.29	96	41	0	18	113	18	113	3e-34	127
rs:WP_045778785	phosphoribosyl-AMP cyclohydrolase [Methylococcaceae bacterium Sn10-6].	50.00	114	56	1	18	130	7	120	3e-34	127
rs:WP_006544435	phosphoribosyl-AMP cyclohydrolase [Frankia sp. EUN1f].	60.00	95	38	0	18	112	16	110	3e-34	127
rs:WP_021441807	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. EGD-AK9].	51.75	114	54	1	18	130	8	121	3e-34	127
rs:WP_014472927	phosphoribosyl-ATP pyrophosphatase [Arcobacter sp. L].	59.34	91	37	0	24	114	14	104	3e-34	129
rs:WP_041242359	phosphoribosyl-AMP cyclohydrolase [Geodermatophilus obscurus].	54.55	110	49	1	9	117	9	118	3e-34	127
rs:WP_024659879	phosphoribosyl-AMP cyclohydrolase [Pseudomonas syringae].	52.63	114	53	1	18	130	8	121	3e-34	127
rs:WP_009141035	phosphoribosyl-AMP cyclohydrolase [Collinsella tanakaei].	59.38	96	39	0	18	113	6	101	3e-34	126
rs:WP_005739553	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas syringae group].	52.63	114	53	1	18	130	8	121	3e-34	127
rs:WP_043606487	phosphoribosyl-AMP cyclohydrolase, partial [Frankia symbiont of Datisca glomerata].	58.95	95	39	0	18	112	16	110	3e-34	126
rs:WP_046829486	phosphoribosyl-AMP cyclohydrolase [Afipia sp. LC387].	51.38	109	51	1	19	125	21	129	3e-34	127
rs:WP_012634837	phosphoribosyl-ATP pyrophosphatase [[Clostridium] cellulolyticum].	46.28	121	59	1	16	130	6	126	3e-34	129
rs:WP_023274899	hypothetical protein [Mucispirillum schaedleri].	59.34	91	37	0	23	113	11	101	3e-34	126
tr:B9E173_CLOK1	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.61	92	39	0	22	113	21	112	3e-34	126
rs:WP_026845157	phosphoribosyl-AMP cyclohydrolase [Geodermatophilaceae bacterium URHA0031].	52.68	112	46	1	9	113	2	113	3e-34	127
tr:F5SGL2_9BACL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	51.79	112	54	0	14	125	6	117	3e-34	129
rs:WP_028929453	phosphoribosyl-AMP cyclohydrolase [Pseudonocardia asaccharolytica].	62.11	95	36	0	18	112	24	118	3e-34	127
rs:WP_038411126	phosphoribosyl-AMP cyclohydrolase [Pseudomonas cremoricolorata].	53.51	114	52	1	18	130	8	121	3e-34	127
tr:U1H9I0_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	61.54	91	35	0	26	116	1	91	3e-34	126
rs:WP_046650636	phosphoribosyl-AMP cyclohydrolase [Corynebacterium xerosis].	62.11	95	36	0	18	112	24	118	3e-34	126
rs:WP_003196931	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	52.63	114	53	1	18	130	8	121	3e-34	127
rs:WP_004286214	phosphoribosyl-AMP cyclohydrolase [Neisseria weaveri].	53.91	115	52	1	18	131	9	123	3e-34	127
rs:WP_008285293	phosphoribosyl-AMP cyclohydrolase [gamma proteobacterium HTCC5015].	46.96	115	60	1	17	130	7	121	3e-34	127
rs:WP_021161852	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. AU4i].	50.00	114	56	1	5	117	2	115	3e-34	127
tr:X1QJH4_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_C02169 {ECO:0000313|EMBL:GAI68403.1};	55.32	94	42	0	20	113	9	102	3e-34	127
tr:A0A087D686_9BIFI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.95	111	41	1	11	112	1	111	3e-34	127
tr:S4XBX7_9CORY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	55.79	95	42	0	18	112	36	130	3e-34	127
rs:WP_019537110	phosphoribosyl-ATP pyrophosphatase [Paenibacillus ginsengihumi].	51.24	121	58	1	1	120	1	121	3e-34	129
rs:WP_041308546	phosphoribosyl-AMP cyclohydrolase [Intrasporangium calvum].	59.79	97	39	0	16	112	10	106	3e-34	126
rs:WP_022812489	phosphoribosyl-ATP pyrophosphatase [Poribacteria bacterium WGA-3G].	53.77	106	49	0	16	121	5	110	3e-34	127
rs:WP_035038242	phosphoribosyl-AMP cyclohydrolase [Devosia sp. DBB001].	55.05	109	45	2	19	123	25	133	3e-34	127
sp:HIS2_THEP3	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	51.75	114	55	0	18	131	8	121	3e-34	129
rs:WP_033245170	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Actinomycetales].	55.66	106	47	0	18	123	11	116	3e-34	126
rs:WP_029707390	phosphoribosyl-AMP cyclohydrolase [Rhodoferax saidenbachensis].	47.86	117	57	1	18	130	7	123	3e-34	127
rs:WP_035903231	phosphoribosyl-AMP cyclohydrolase [Knoellia subterranea].	57.14	98	42	0	15	112	9	106	3e-34	126
rs:WP_033055339	phosphoribosyl-AMP cyclohydrolase [Pseudomonas mandelii].	52.63	114	53	1	18	130	8	121	3e-34	127
rs:WP_027354873	phosphoribosyl-AMP cyclohydrolase [Desulfosarcina sp. BuS5].	56.19	105	44	2	18	120	4	108	3e-34	126
tr:H1QPN1_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	59.60	99	40	0	18	116	25	123	3e-34	127
rs:WP_016656193	phosphoribosyl-AMP cyclohydrolase [Acinetobacter rudis].	52.25	111	49	1	18	128	28	134	3e-34	127
rs:WP_039855245	phosphoribosyl-AMP cyclohydrolase [Neisseria mucosa].	53.04	115	53	1	18	131	9	123	3e-34	127
rs:WP_003863879	phosphoribosyl-AMP cyclohydrolase [Holdemanella biformis].	59.14	93	38	0	21	113	8	100	3e-34	126
rs:WP_045160226	phosphoribosyl-AMP cyclohydrolase [Pseudomonas stutzeri].	52.63	114	53	1	18	130	7	120	3e-34	127
rs:WP_025460931	phosphoribosyl-AMP cyclohydrolase [Neisseria meningitidis].	53.45	116	53	1	17	131	8	123	3e-34	127
rs:WP_029052754	phosphoribosyl-ATP pyrophosphatase [Sporosarcina ureae].	47.83	115	60	0	9	123	2	116	3e-34	129
rs:WP_021870126	hypothetical protein [Clostridium sp. CAG:7].	59.05	105	43	0	14	118	234	338	3e-34	133
tr:B2SZ58_BURPP	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	55.45	101	44	1	18	117	13	113	3e-34	127
rs:WP_027797352	phosphoribosyl-AMP cyclohydrolase [Burkholderia acidipaludis].	52.21	113	50	2	18	126	15	127	3e-34	127
rs:WP_016783169	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fragi].	51.75	114	54	1	18	130	8	121	3e-34	127
rs:WP_014406124	phosphoribosyl-AMP cyclohydrolase [Methanocella conradii].	62.64	91	34	0	23	113	8	98	3e-34	126
rs:WP_041759045	phosphoribosyl-AMP cyclohydrolase [Burkholderia phytofirmans].	55.45	101	44	1	18	117	12	112	3e-34	127
rs:WP_043248683	phosphoribosyl-AMP cyclohydrolase [Pseudomonas knackmussii].	51.75	114	54	1	18	130	8	121	3e-34	127
rs:WP_027995540	phosphoribosyl-AMP cyclohydrolase [Simplicispira psychrophila].	48.72	117	56	1	18	130	7	123	3e-34	127
tr:B4XNI7_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	48.31	118	60	1	5	121	2	119	3e-34	127
rs:WP_006400577	phosphoribosyl-AMP cyclohydrolase [Burkholderia multivorans].	46.83	126	63	2	5	126	2	127	3e-34	127
rs:WP_039366640	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacteria].	50.00	114	56	1	5	117	2	115	3e-34	127
tr:A0A0D8HET0_9ACTN	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:KJF16322.1}; EC=3.5.4.19 {ECO:0000313|EMBL:KJF16322.1};	59.79	97	38	1	18	113	12	108	3e-34	126
rs:WP_040658717	phosphoribosyl-AMP cyclohydrolase [Neisseria bacilliformis].	51.30	115	55	1	18	131	9	123	3e-34	127
rs:WP_021049676	phosphoribosyl-AMP cyclohydrolase [Haloquadratum walsbyi].	52.17	115	53	2	8	121	50	163	3e-34	128
rs:WP_019412272	phosphoribosyl-AMP cyclohydrolase [Pseudomonas psychrophila].	51.75	114	54	1	18	130	8	121	3e-34	127
rs:WP_024574947	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Afipia].	53.21	109	49	1	19	125	20	128	3e-34	127
rs:WP_036314925	phosphoribosyl-AMP cyclohydrolase [Microbacterium sp. B24].	58.95	95	39	0	18	112	12	106	3e-34	126
rs:WP_005512677	phosphoribosyl-AMP cyclohydrolase [Rhodococcus equi].	57.69	104	44	0	18	121	11	114	3e-34	126
rs:WP_009549237	phosphoribosyl-AMP cyclohydrolase [Burkholderiales bacterium JOSHI_001].	46.67	120	60	1	16	131	5	124	3e-34	127
tr:D1A720_THECD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	58.95	95	39	0	18	112	19	113	3e-34	126
rs:WP_025155731	phosphoribosyl-AMP cyclohydrolase [Leifsonia aquatica].	61.05	95	37	0	18	112	12	106	3e-34	126
tr:C5TKT2_NEIFL	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.14	117	55	1	16	131	26	142	3e-34	127
rs:WP_020472033	phosphoribosyl-AMP cyclohydrolase [Zavarzinella formosa].	51.67	120	51	2	12	130	4	117	3e-34	126
rs:WP_022375962	phosphoribosyl-ATP diphosphatase [Clostridium sp. CAG:62].	54.46	112	49	1	2	113	200	309	3e-34	133
rs:WP_008320168	phosphoribosyl-AMP cyclohydrolase [Haloferax mucosum].	54.37	103	47	0	15	117	2	104	3e-34	126
rs:WP_046096067	phosphoribosyl-AMP cyclohydrolase [Corynebacterium ulcerans].	56.88	109	43	2	7	112	5	112	3e-34	126
rs:WP_034584259	phosphoribosyl-AMP cyclohydrolase [Clostridium acetobutylicum].	56.44	101	42	1	24	122	15	115	3e-34	126
rs:WP_022596396	phosphoribosyl-AMP cyclohydrolase [Rhodococcus equi].	57.69	104	44	0	18	121	11	114	3e-34	126
rs:WP_028631944	phosphoribosyl-AMP cyclohydrolase [Pseudomonas parafulva].	52.63	114	53	1	18	130	8	121	3e-34	126
rs:WP_012101688	phosphoribosyl-AMP cyclohydrolase [Clostridium kluyveri].	57.61	92	39	0	22	113	12	103	3e-34	126
tr:E6S9F3_INTC7	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	61.05	95	37	0	18	112	21	115	3e-34	127
rs:WP_047272973	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	51.75	114	54	1	18	130	8	121	3e-34	127
tr:D2ZSV5_NEIMU	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	53.04	115	53	1	18	131	12	126	3e-34	127
rs:WP_025233025	phosphoribosyl-ATP diphosphatase [Clostridium sp. ASBs410].	60.95	105	39	1	9	113	223	325	3e-34	133
rs:WP_035061274	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Desulfovibrio].	62.50	96	35	1	26	120	1	96	4e-34	126
rs:WP_013090692	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. CCGE1002].	55.45	101	44	1	18	117	13	113	4e-34	127
rs:WP_036921909	imidazole glycerol phosphate synthase [Prochlorococcus marinus].	52.25	111	52	1	9	118	3	113	4e-34	129
rs:WP_015748283	phosphoribosyl-AMP cyclohydrolase [Nakamurella multipartita].	62.11	95	36	0	18	112	14	108	4e-34	126
rs:WP_003438738	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	51.75	114	54	1	18	130	8	121	4e-34	127
sp:HIS3_RHORT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.77	106	49	0	16	121	15	120	4e-34	127
rs:WP_019924119	phosphoribosyl-AMP cyclohydrolase [Duganella zoogloeoides].	52.38	105	49	1	18	121	17	121	4e-34	127
rs:WP_024295490	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Lachnoclostridium].	63.54	96	35	0	18	113	231	326	4e-34	133
rs:WP_013434866	phosphoribosyl-AMP cyclohydrolase [Burkholderia rhizoxinica].	51.33	113	51	2	18	126	10	122	4e-34	127
rs:WP_041441860	phosphoribosyl-AMP cyclohydrolase [Thermomonospora curvata].	58.95	95	39	0	18	112	16	110	4e-34	126
rs:WP_045670459	phosphoribosyl-ATP pyrophosphatase [Paenibacillus beijingensis].	55.56	99	44	0	18	116	19	117	4e-34	129
rs:WP_019369486	phosphoribosyl-AMP cyclohydrolase [Sphingomonas sp. ATCC 31555].	57.84	102	43	0	19	120	14	115	4e-34	126
sp:HIS3_NEIG1	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.91	115	52	1	18	131	9	123	4e-34	126
rs:WP_002855722	phosphoribosyl-AMP cyclohydrolase [Micrococcus luteus].	56.73	104	45	0	9	112	4	107	4e-34	126
rs:WP_025845170	phosphoribosyl-ATP pyrophosphatase [Paenibacillus ehimensis].	52.94	119	55	1	2	120	1	118	4e-34	129
rs:WP_013626533	phosphoribosyl-AMP cyclohydrolase [Planctomyces brasiliensis].	54.29	105	47	1	14	117	20	124	4e-34	127
rs:WP_007948971	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. GM21].	52.63	114	53	1	18	130	8	121	4e-34	127
rs:WP_042319495	phosphoribosyl-AMP cyclohydrolase [Burkholderia caledonica].	54.29	105	47	1	18	121	12	116	4e-34	127
rs:WP_016834686	phosphoribosyl-AMP cyclohydrolase [Herbaspirillum lusitanum].	51.40	107	51	1	16	121	9	115	4e-34	127
rs:WP_040353155	phosphoribosyl-AMP cyclohydrolase [Blastopirellula marina].	62.22	90	34	0	24	113	16	105	4e-34	126
rs:WP_025110285	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. H1h].	52.63	114	53	1	18	130	8	121	4e-34	126
rs:WP_036382780	phosphoribosyl-AMP cyclohydrolase [Micrococcus luteus].	56.73	104	45	0	9	112	4	107	4e-34	126
rs:WP_036279359	phosphoribosyl-AMP cyclohydrolase [Microbacterium sp. CH12i].	56.86	102	44	0	11	112	4	105	4e-34	126
rs:WP_008275113	phosphoribosyl-ATP pyrophosphatase [Cyanothece sp. CCY0110].	55.88	102	44	1	18	118	19	120	4e-34	129
rs:WP_006412399	phosphoribosyl-AMP cyclohydrolase [Burkholderia multivorans].	46.83	126	63	2	5	126	2	127	4e-34	127
tr:H5UQ66_9MICO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	58.76	97	40	0	18	114	9	105	4e-34	126
rs:WP_027617405	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. URHB0015].	52.63	114	53	1	18	130	8	121	4e-34	126
rs:WP_010264822	phosphoribosyl-AMP cyclohydrolase [Corynebacterium bovis].	50.88	114	53	1	2	112	1	114	4e-34	126
rs:WP_040761403	imidazole glycerol phosphate synthase [[Clostridium] termitidis].	53.40	103	48	0	17	119	7	109	4e-34	129
tr:S0FRD3_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	53.40	103	48	0	17	119	8	110	4e-34	129
rs:WP_022098588	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [Eubacterium eligens CAG:72].	54.95	111	47	1	6	113	244	354	4e-34	132
rs:WP_041102690	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. 2385].	56.73	104	45	0	9	112	4	107	4e-34	126
rs:WP_039603059	phosphoribosyl-AMP cyclohydrolase [Pseudomonas putida].	52.63	114	53	1	18	130	8	121	4e-34	126
rs:WP_007623560	phosphoribosyl-AMP cyclohydrolase [Gordonia soli].	58.49	106	43	1	10	114	2	107	4e-34	126
rs:WP_022303178	phosphoribosyl-AMP cyclohydrolase [Firmicutes bacterium CAG:227].	54.87	113	47	2	11	122	1	110	4e-34	126
rs:WP_021221365	phosphoribosyl-AMP cyclohydrolase [Pseudomonas alcaligenes].	56.31	103	44	1	18	119	8	110	4e-34	126
rs:WP_002255001	phosphoribosyl-AMP cyclohydrolase [Neisseria meningitidis].	52.59	116	54	1	17	131	8	123	4e-34	126
tr:B7KA15_CYAP7	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	58.59	99	40	1	18	115	15	113	4e-34	129
rs:WP_025103481	phosphoribosyl-AMP cyclohydrolase [Microbacterium paraoxydans].	55.86	111	48	1	4	114	6	115	4e-34	126
rs:WP_013674980	phosphoribosyl-AMP cyclohydrolase [Pseudonocardia dioxanivorans].	61.05	95	37	0	18	112	17	111	4e-34	126
rs:WP_006021225	phosphoribosyl-AMP cyclohydrolase [Afipia broomeae].	53.21	109	49	1	19	125	20	128	4e-34	127
rs:WP_022958441	phosphoribosyl-AMP cyclohydrolase [Spongiibacter tropicus].	51.75	114	54	1	18	130	13	126	4e-34	126
rs:WP_044658970	phosphoribosyl-AMP cyclohydrolase [Micrococcus sp. MS-ASIII-49].	56.73	104	45	0	9	112	4	107	4e-34	126
rs:WP_029430373	phosphoribosyl-AMP cyclohydrolase [Blastococcus sp. URHD0036].	58.33	96	40	0	18	113	18	113	4e-34	126
rs:WP_028621769	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. Ant30-3].	52.63	114	53	1	18	130	8	121	4e-34	126
rs:WP_015602078	phosphoribosyl-AMP cyclohydrolase [Burkholderia thailandensis].	52.21	113	50	2	18	126	14	126	4e-34	126
rs:WP_015203093	phosphoribosyl-AMP cyclohydrolase [Crinalium epipsammum].	57.58	99	41	1	18	115	18	116	4e-34	129
sp:HIS3_CAUCN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	56.31	103	43	1	19	119	24	126	4e-34	127
tr:A0A090MJ91_AFIFE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	50.89	112	52	1	19	127	20	131	4e-34	127
tr:B5IQD9_9CHRO	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	62.89	97	35	1	18	113	2	98	4e-34	129
rs:WP_035570644	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Burkholderia].	52.21	113	50	2	18	126	12	124	4e-34	126
rs:WP_035479620	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Burkholderia].	55.45	101	44	1	18	117	12	112	4e-34	126
rs:WP_008293195	phosphoribosyl-AMP cyclohydrolase [Congregibacter litoralis].	51.75	114	54	1	18	130	13	126	4e-34	126
rs:WP_035962112	phosphoribosyl-AMP cyclohydrolase [Kocuria marina].	61.05	95	37	0	18	112	29	123	4e-34	126
rs:WP_015534908	phosphoribosyl-ATP pyrophosphohydrolase [Coprococcus sp. CAG:131].	56.60	106	44	1	9	114	218	321	4e-34	133
tr:D2SA11_GEOOG	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.55	110	49	1	9	117	22	131	4e-34	126
tr:B1G8G9_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.21	113	50	2	18	126	13	125	4e-34	126
rs:WP_005885926	phosphoribosyl-AMP cyclohydrolase [Brevibacterium mcbrellneri].	56.25	96	42	0	17	112	5	100	4e-34	125
rs:WP_035493359	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. JPY366].	55.45	101	44	1	18	117	12	112	4e-34	126
tr:B4XND3_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	46.83	126	63	2	5	126	2	127	4e-34	126
rs:WP_006166241	phosphoribosyl-AMP cyclohydrolase [Natrialba chahannaoensis].	58.00	100	42	0	18	117	215	314	4e-34	132
rs:WP_018058462	phosphoribosyl-AMP cyclohydrolase [Oxalobacteraceae bacterium JGI 0001004-K23].	54.64	97	43	1	18	113	16	112	4e-34	127
sp:HIS3_ARCFU	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	58.00	100	42	0	18	117	3	102	4e-34	125
tr:B4XN61_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	48.31	118	60	1	5	121	2	119	4e-34	126
rs:WP_043369218	imidazole glycerol phosphate synthase [Cyanobium sp. PCC 7001].	62.24	98	36	1	17	113	4	101	4e-34	129
rs:WP_017540485	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Nocardiopsis].	60.00	95	38	0	18	112	26	120	4e-34	126
rs:WP_028633958	phosphoribosyl-AMP cyclohydrolase [Pseudomonas parafulva].	56.07	107	46	1	18	124	23	128	4e-34	126
rs:WP_015302315	phosphoribosyl-AMP cyclohydrolase [Halovivax ruber].	58.33	96	40	0	18	113	6	101	4e-34	126
tr:A0A0C5J9T4_9RHOO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	51.92	104	49	1	17	119	17	120	5e-34	126
rs:WP_005783996	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	53.51	114	52	1	18	130	8	121	5e-34	126
rs:WP_035627450	imidazole glycerol phosphate synthase [Lachnospiraceae bacterium C6A11].	62.92	89	33	0	26	114	1	89	5e-34	128
rs:WP_044296843	phosphoribosyl-ATP diphosphatase [Robinsoniella peoriensis].	59.18	98	40	0	16	113	228	325	5e-34	133
rs:WP_040039260	phosphoribosyl-AMP cyclohydrolase [Herbaspirillum sp. TSA66].	51.40	107	51	1	16	121	9	115	5e-34	126
rs:WP_035999116	imidazole glycerol phosphate synthase [Leptolyngbya sp. JSC-1].	57.58	99	41	1	18	115	17	115	5e-34	129
rs:WP_034110127	phosphoribosyl-AMP cyclohydrolase [Comamonadaceae bacterium BICA1-1].	55.45	101	41	1	17	113	7	107	5e-34	127
rs:WP_006516268	phosphoribosyl-AMP cyclohydrolase [Leptolyngbya sp. PCC 7375].	56.86	102	43	1	15	115	13	114	5e-34	129
rs:WP_041238250	imidazole glycerol phosphate synthase [Cyanothece sp. PCC 7424].	58.59	99	40	1	18	115	12	110	5e-34	129
rs:WP_044289962	phosphoribosyl-ATP diphosphatase [Robinsoniella sp. KNHs210].	59.18	98	40	0	16	113	228	325	5e-34	133
rs:WP_009138677	phosphoribosyl-AMP cyclohydrolase [Slackia piriformis].	53.27	107	50	0	11	117	1	107	5e-34	125
rs:WP_013756679	phosphoribosyl-ATP pyrophosphatase [Thermodesulfobium narugense].	53.77	106	48	1	15	119	6	111	5e-34	129
rs:WP_008058098	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. GM78].	56.31	103	44	1	18	119	8	110	5e-34	126
tr:E8YGL3_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	55.45	101	44	1	18	117	13	113	5e-34	126
rs:WP_021060465	phosphoribosyl-AMP cyclohydrolase [Halonotius sp. J07HN6].	54.81	104	46	1	18	121	7	109	5e-34	126
rs:WP_019176489	hypothetical protein [Methanomassiliicoccus luminyensis].	59.18	98	40	0	15	112	2	99	5e-34	128
rs:WP_034661759	phosphoribosyl-AMP cyclohydrolase [Corynebacterium tuscaniense].	61.05	95	36	1	18	112	16	109	5e-34	125
sp:HIS3_BURCJ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.00	114	56	1	5	117	2	115	5e-34	126
rs:WP_036209613	phosphoribosyl-AMP cyclohydrolase [Massilia sp. LC238].	52.53	99	46	1	16	113	9	107	5e-34	126
rs:WP_028213288	phosphoribosyl-AMP cyclohydrolase [Burkholderia mimosarum].	49.18	122	57	2	1	117	1	122	5e-34	127
rs:WP_040632927	phosphoribosyl-AMP cyclohydrolase [Mobilicoccus pelagius].	58.76	97	40	0	18	114	17	113	5e-34	126
tr:X1KWQ8_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S28844 {ECO:0000313|EMBL:GAH86418.1}; Flags: Fragment;	50.96	104	51	0	19	122	16	119	5e-34	126
rs:WP_013719580	phosphoribosyl-AMP cyclohydrolase [Methanosaeta concilii].	58.06	93	39	0	25	117	5	97	5e-34	125
rs:WP_047291438	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	51.75	114	54	1	18	130	8	121	5e-34	126
rs:WP_026855320	phosphoribosyl-AMP cyclohydrolase [Geodermatophilaceae bacterium URHB0062].	54.13	109	49	1	6	113	10	118	5e-34	126
rs:WP_007229907	phosphoribosyl-AMP cyclohydrolase [marine gamma proteobacterium HTCC2148].	57.14	105	44	1	18	121	7	111	5e-34	126
rs:WP_015419458	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Hydrogenobaculum].	51.92	104	49	1	11	113	1	104	5e-34	128
rs:WP_003220851	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	52.63	114	53	1	18	130	8	121	5e-34	126
rs:WP_027866458	phosphoribosyl-AMP cyclohydrolase [Massilia alkalitolerans].	52.53	99	46	1	16	113	9	107	5e-34	126
rs:WP_024919069	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Afipia].	53.21	109	49	1	19	125	20	128	5e-34	126
rs:WP_022361086	phosphoribosyl-ATP diphosphatase [Bacteroides pectinophilus CAG:437].	59.18	98	40	0	16	113	230	327	5e-34	133
rs:WP_030523760	phosphoribosyl-AMP cyclohydrolase [Nocardia rhamnosiphila].	59.60	99	40	0	18	116	13	111	5e-34	125
rs:WP_008419144	phosphoribosyl-AMP cyclohydrolase [Halalkalicoccus jeotgali].	50.83	120	56	1	14	130	3	122	5e-34	126
tr:I6A6R3_BURTH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.21	113	50	2	18	126	15	127	5e-34	126
rs:WP_013586638	phosphoribosyl-AMP cyclohydrolase [Microbacterium testaceum].	58.95	95	39	0	18	112	6	100	5e-34	125
rs:WP_009913768	phosphoribosyl-AMP cyclohydrolase [Burkholderia thailandensis].	52.21	113	50	2	18	126	14	126	5e-34	126
rs:WP_043517057	phosphoribosyl-AMP cyclohydrolase [Halomonas sp. BC04].	50.39	129	57	2	4	125	5	133	5e-34	126
rs:WP_039909513	phosphoribosyl-AMP cyclohydrolase [Acinetobacter beijerinckii].	50.00	114	55	1	2	113	10	123	5e-34	126
rs:WP_044918044	hypothetical protein [Lachnospiraceae bacterium MA2020].	52.10	119	50	1	2	113	217	335	5e-34	133
rs:WP_028576341	phosphoribosyl-AMP cyclohydrolase [Desulfomicrobium escambiense].	65.22	92	31	1	23	113	10	101	5e-34	126
rs:WP_008149521	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. GM41(2012)].	52.63	114	53	1	18	130	8	121	6e-34	126
rs:WP_026320399	phosphoribosyl-AMP cyclohydrolase [Brachymonas chironomi].	46.61	118	59	1	18	131	11	128	6e-34	126
rs:WP_046704733	phosphoribosyl-AMP cyclohydrolase [Streptomyces europaeiscabiei].	53.39	118	50	2	9	121	23	140	6e-34	126
rs:WP_047221819	phosphoribosyl-AMP cyclohydrolase [Frankia sp. BMG5.1].	58.95	95	39	0	18	112	27	121	6e-34	127
tr:N9FH26_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	50.00	114	55	1	2	113	12	125	6e-34	126
tr:K1T971_9ZZZZ	SubName: Full=Phosphoribosyl-ATP diphosphatase {ECO:0000313|EMBL:EKC66108.1}; Flags: Fragment;	54.37	103	47	0	14	116	6	108	6e-34	125
rs:WP_045255107	phosphoribosyl-AMP cyclohydrolase [Microbacterium foliorum].	57.89	95	40	0	18	112	11	105	6e-34	125
tr:A0A085FNA5_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.53	99	46	1	16	113	7	105	6e-34	126
rs:WP_042329264	phosphoribosyl-AMP cyclohydrolase [Burkholderia ginsengisoli].	54.46	101	45	1	18	117	12	112	6e-34	126
rs:WP_007297394	phosphoribosyl-AMP cyclohydrolase [Rhodococcus imtechensis].	56.60	106	46	0	16	121	9	114	6e-34	125
rs:WP_027750482	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. CNH287].	61.05	95	37	0	18	112	16	110	6e-34	125
rs:WP_041444997	phosphoribosyl-ATP pyrophosphatase [Syntrophobotulus glycolicus].	50.91	110	54	0	4	113	2	111	6e-34	129
rs:WP_013076128	phosphoribosyl-ATP pyrophosphatase [Kyrpidia tusciae].	50.41	121	55	1	13	128	2	122	6e-34	129
rs:WP_028951280	phosphoribosyl-ATP pyrophosphatase [Sulfurihydrogenibium subterraneum].	42.98	121	66	2	11	129	2	121	6e-34	128
rs:WP_007996675	phosphoribosyl-AMP cyclohydrolase [Halorubrum arcis].	49.57	117	54	1	1	117	1	112	6e-34	126
rs:WP_013449344	phosphoribosyl-AMP cyclohydrolase [Neisseria lactamica].	53.04	115	53	1	18	131	9	123	6e-34	126
rs:WP_028988601	phosphoribosyl-AMP cyclohydrolase [Thermithiobacillus tepidarius].	57.73	97	41	0	17	113	13	109	6e-34	129
rs:WP_012823015	phosphoribosyl-AMP cyclohydrolase [Halothiobacillus neapolitanus].	52.21	113	53	1	17	128	9	121	6e-34	126
rs:WP_019271785	phosphoribosyl-AMP cyclohydrolase [Neisseria lactamica].	52.59	116	54	1	17	131	8	123	6e-34	126
rs:WP_028336163	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium elkanii].	51.33	113	55	0	19	131	19	131	6e-34	126
rs:WP_040063627	phosphoribosyl-AMP cyclohydrolase [Pseudomonas batumici].	50.88	114	55	1	18	130	8	121	6e-34	126
rs:WP_015738359	phosphoribosyl-ATP pyrophosphatase [Ammonifex degensii].	52.59	116	52	2	11	125	1	114	6e-34	129
rs:WP_003790152	phosphoribosyl-AMP cyclohydrolase [Kingella kingae].	50.00	122	60	1	11	131	1	122	6e-34	126
tr:A2WD87_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	46.92	130	63	3	1	126	1	128	6e-34	126
rs:WP_040260091	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. CB1].	51.75	114	54	1	18	130	8	121	6e-34	126
rs:WP_028464370	phosphoribosyl-AMP cyclohydrolase [Nisaea denitrificans].	55.26	114	46	3	19	130	27	137	6e-34	126
rs:WP_044091968	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium thermacidophilum].	60.00	95	38	0	18	112	26	120	6e-34	126
sp:HIS3_PSEPF	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.63	114	53	1	18	130	8	121	6e-34	126
rs:WP_020657716	phosphoribosyl-AMP cyclohydrolase [Amycolatopsis benzoatilytica].	60.82	97	38	0	18	114	11	107	6e-34	125
rs:WP_007928329	phosphoribosyl-AMP cyclohydrolase [Janibacter hoylei].	60.00	95	38	0	18	112	20	114	6e-34	125
sp:HIS3_BURPS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.21	113	50	2	18	126	15	127	6e-34	126
rs:WP_009906356	phosphoribosyl-AMP cyclohydrolase [Burkholderia thailandensis].	52.21	113	50	2	18	126	14	126	6e-34	126
sp:HIS3_BURM7	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.21	113	50	2	18	126	14	126	6e-34	126
sp:HIS3_METPP	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.27	107	46	1	18	120	7	113	6e-34	126
rs:WP_007879643	phosphoribosyl-AMP cyclohydrolase [Herbaspirillum sp. CF444].	50.47	107	52	1	16	121	9	115	6e-34	127
rs:WP_023978110	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Asaia].	60.20	98	38	1	17	113	17	114	6e-34	126
rs:WP_041938191	phosphoribosyl-AMP cyclohydrolase [Gallionella capsiferriformans].	53.40	103	47	1	18	119	15	117	7e-34	126
rs:WP_026405869	phosphoribosyl-AMP cyclohydrolase [Actinomadura rifamycini].	57.43	101	43	0	18	118	19	119	7e-34	126
rs:WP_019495160	phosphoribosyl-ATP pyrophosphatase [Calothrix sp. PCC 7103].	54.90	102	45	1	15	115	14	115	7e-34	128
sp:HIS3_RHOE4	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	55.14	107	48	0	16	122	9	115	7e-34	125
rs:WP_007899278	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	52.63	114	53	1	18	130	8	121	7e-34	126
rs:WP_035973155	phosphoribosyl-AMP cyclohydrolase [Burkholderia dolosa].	46.83	126	63	2	5	126	2	127	7e-34	126
rs:WP_043650356	phosphoribosyl-AMP cyclohydrolase [Nocardia thailandica].	60.00	95	38	0	18	112	11	105	7e-34	125
rs:WP_012195135	phosphoribosyl-ATP pyrophosphatase [Prochlorococcus marinus].	55.34	103	44	2	12	113	7	108	7e-34	128
tr:B4XN88_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	48.31	118	60	1	5	121	2	119	7e-34	126
rs:WP_007936797	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	52.63	114	53	1	18	130	8	121	7e-34	126
rs:WP_009425992	phosphoribosyl-AMP cyclohydrolase [Neisseria sp. oral taxon 020].	51.30	115	55	1	18	131	9	123	7e-34	126
rs:WP_008516132	phosphoribosyl-ATP pyrophosphatase [Dethiobacter alkaliphilus].	51.82	110	52	1	16	125	3	111	7e-34	128
rs:WP_046747128	phosphoribosyl-AMP cyclohydrolase [Microbacterium sp. Ag1].	50.88	114	56	0	1	114	1	114	7e-34	125
rs:WP_022963645	phosphoribosyl-AMP cyclohydrolase [Pseudomonas pelagia].	52.59	116	54	1	16	130	12	127	7e-34	126
rs:WP_007345196	phosphoribosyl-AMP cyclohydrolase [Halorubrum terrestre].	49.57	117	54	1	1	117	1	112	7e-34	125
rs:WP_029287477	phosphoribosyl-AMP cyclohydrolase [Cellulomonas sp. HZM].	59.05	105	42	1	9	112	5	109	7e-34	126
rs:WP_008400812	MULTISPECIES: imidazole glycerol phosphate synthase [Clostridium].	57.55	106	43	1	9	114	214	317	7e-34	132
rs:WP_015396737	phosphoribosyl-AMP cyclohydrolase [Candidatus Kinetoplastibacterium oncopeltii].	53.92	102	46	1	17	117	11	112	7e-34	126
rs:WP_028566979	phosphoribosyl-AMP cyclohydrolase [Salisaeta longa].	55.34	103	46	0	18	120	11	113	7e-34	125
rs:WP_039676270	phosphoribosyl-AMP cyclohydrolase, partial [Corynebacterium minutissimum].	62.11	95	35	1	18	112	14	107	7e-34	125
rs:WP_029911396	phosphoribosyl-AMP cyclohydrolase [Caulobacter sp. UNC358MFTsu5.1].	57.55	106	43	1	17	120	22	127	7e-34	126
rs:WP_017616923	phosphoribosyl-AMP cyclohydrolase [Nocardiopsis gilva].	60.00	95	38	0	18	112	26	120	7e-34	125
rs:WP_022898277	phosphoribosyl-AMP cyclohydrolase [Corynebacterium-like bacterium B27].	63.44	93	34	0	20	112	13	105	7e-34	125
rs:WP_034339903	imidazole glycerol phosphate synthase [Deinococcus misasensis].	56.70	97	42	0	18	114	10	106	7e-34	128
rs:WP_012547727	phosphoribosyl-ATP pyrophosphatase [Dictyoglomus thermophilum].	53.40	103	48	0	18	120	15	117	7e-34	128
tr:X0XMY2_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_S28509 {ECO:0000313|EMBL:GAG37978.1}; Flags: Fragment;	53.85	104	48	0	18	121	4	107	7e-34	127
tr:H6SIJ3_RHOPH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	58.00	100	42	0	18	117	52	151	8e-34	127
rs:WP_040777184	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Nocardia].	57.89	95	40	0	18	112	11	105	8e-34	125
rs:WP_045538817	phosphoribosyl-AMP cyclohydrolase [Gordonia sp. no. 9].	59.60	99	40	0	16	114	9	107	8e-34	125
rs:WP_010479004	phosphoribosyl-ATP pyrophosphatase [Acaryochloris sp. CCMEE 5410].	55.56	108	45	2	9	115	4	109	8e-34	128
rs:WP_008952122	phosphoribosyl-AMP cyclohydrolase [Pseudogulbenkiania ferrooxidans].	50.88	114	55	1	18	130	7	120	8e-34	125
sp:HIS3_BURCA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	46.03	126	64	2	5	126	2	127	8e-34	126
rs:WP_017878334	phosphoribosyl-AMP cyclohydrolase [Janthinobacterium sp. CG3].	48.36	122	61	2	2	122	1	121	8e-34	126
tr:D9SC17_GALCS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	53.40	103	47	1	18	119	19	121	8e-34	126
rs:WP_004038406	hypothetical protein [Clostridium sp. ASF356].	56.25	96	42	0	18	113	7	102	8e-34	125
tr:K8PE53_9BRAD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	51.38	109	51	1	19	125	21	129	8e-34	126
rs:WP_046012809	phosphoribosyl-AMP cyclohydrolase [Microbacterium sp. SA39].	59.79	97	39	0	18	114	11	107	8e-34	125
rs:WP_012734432	phosphoribosyl-AMP cyclohydrolase [Burkholderia glumae].	49.57	117	58	1	6	121	4	120	8e-34	126
rs:WP_009497825	phosphoribosyl-ATP pyrophosphatase [Sporosarcina newyorkensis].	50.94	106	52	0	9	114	2	107	8e-34	128
rs:WP_046052146	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	56.31	103	44	1	18	119	8	110	8e-34	125
rs:WP_027719819	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio sp. Dsv1].	61.86	97	36	1	25	120	1	97	8e-34	125
rs:WP_033230902	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Rhodococcus].	55.66	106	47	0	16	121	9	114	8e-34	125
rs:WP_040301878	phosphoribosyl-AMP cyclohydrolase [Afipia clevelandensis].	51.38	109	51	1	19	125	27	135	8e-34	126
rs:WP_037960884	phosphoribosyl-ATP diphosphatase [Sulfurospirillum sp. SCADC].	53.92	102	47	0	16	117	7	108	8e-34	128
rs:WP_035836478	phosphoribosyl-AMP cyclohydrolase [Cryobacterium roopkundense].	54.31	116	43	3	13	128	7	112	8e-34	125
tr:F0T0L4_SYNGF	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	50.91	110	54	0	4	113	19	128	8e-34	129
rs:WP_019497580	phosphoribosyl-AMP cyclohydrolase [Calothrix sp. PCC 7103].	56.00	100	43	1	18	116	11	110	8e-34	125
rs:WP_045061960	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. ES3-33].	52.63	114	53	1	18	130	8	121	8e-34	125
rs:WP_023533064	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	56.31	103	44	1	18	119	8	110	8e-34	125
rs:WP_006895382	phosphoribosyl-AMP cyclohydrolase [Gordonia sihwensis].	59.60	99	40	0	16	114	9	107	8e-34	125
rs:WP_010402117	phosphoribosyl-AMP cyclohydrolase [Janthinobacterium lividum].	49.15	118	55	2	18	130	17	134	8e-34	126
rs:WP_006630428	phosphoribosyl-AMP cyclohydrolase [Halorubrum tebenquichense].	48.00	125	58	2	1	123	1	120	8e-34	125
rs:WP_030129235	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. QTF5].	52.63	114	53	1	18	130	8	121	8e-34	125
rs:WP_040747767	phosphoribosyl-AMP cyclohydrolase [Nocardia transvalensis].	56.73	104	44	1	10	112	2	105	8e-34	125
rs:WP_018610152	phosphoribosyl-AMP cyclohydrolase [Uliginosibacterium gangwonense].	51.79	112	53	1	16	126	7	118	8e-34	125
rs:WP_040436491	phosphoribosyl-AMP cyclohydrolase [Clostridium sartagoforme].	53.27	107	49	1	11	116	3	109	8e-34	125
rs:WP_042056244	phosphoribosyl-AMP cyclohydrolase [Acidomonas methanolica].	53.39	118	49	2	18	129	13	130	9e-34	125
rs:WP_042424954	phosphoribosyl-AMP cyclohydrolase [Comamonas granuli].	49.57	117	55	1	18	130	8	124	9e-34	125
rs:WP_015193583	phosphoribosyl-AMP cyclohydrolase [Stanieria cyanosphaera].	50.00	116	57	1	1	115	1	116	9e-34	128
rs:WP_007835273	phosphoribosyl-AMP cyclohydrolase [Variovorax sp. CF313].	47.86	117	57	1	18	130	7	123	9e-34	125
rs:WP_029263365	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Microbacterium].	58.76	97	40	0	18	114	11	107	9e-34	125
rs:WP_013154196	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Nocardiopsis].	55.24	105	46	1	9	112	4	108	9e-34	125
rs:WP_006065290	phosphoribosyl-AMP cyclohydrolase [Natronorubrum bangense].	47.93	121	60	1	14	131	3	123	9e-34	125
rs:WP_012635184	phosphoribosyl-ATP pyrophosphatase [Halothermothrix orenii].	53.15	111	50	1	11	119	1	111	9e-34	128
rs:WP_007952421	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	51.75	114	54	1	18	130	8	121	9e-34	125
rs:WP_020175839	hypothetical protein [Methyloferula stellata].	51.28	117	53	2	14	126	18	134	9e-34	125
rs:WP_040695501	imidazole glycerol phosphate synthase [Nodosilinea nodulosa].	58.82	102	40	2	18	118	18	118	9e-34	128
rs:WP_020989504	phosphoribosyl-AMP cyclohydrolase [Ruminococcaceae bacterium D16].	55.00	100	45	0	13	112	2	101	9e-34	125
rs:WP_026102133	imidazole glycerol phosphate synthase [Geminocystis herdmanii].	56.57	99	42	1	18	115	18	116	9e-34	128
rs:WP_018852327	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	50.00	114	54	1	2	112	1	114	9e-34	125
tr:A0A0A7LF73_9EURY	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	48.70	115	58	1	16	130	2	115	9e-34	127
rs:WP_018979532	hypothetical protein [Saccharibacter floricola].	53.39	118	48	2	18	129	18	134	9e-34	125
rs:WP_030007100	imidazole glycerol phosphate synthase [Synechococcus sp. NKBG042902].	56.57	99	42	1	18	115	12	110	9e-34	128
rs:WP_025348718	phosphoribosyl-AMP cyclohydrolase [Nocardia nova].	56.60	106	45	1	8	112	2	107	9e-34	125
rs:WP_008441796	phosphoribosyl-AMP cyclohydrolase [Halorubrum californiense].	48.72	117	55	1	1	117	1	112	9e-34	125
rs:WP_009888538	phosphoribosyl-AMP cyclohydrolase [Burkholderia thailandensis].	52.21	113	50	2	18	126	14	126	9e-34	125
rs:WP_014898301	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Burkholderia].	49.12	114	57	1	5	117	2	115	9e-34	125
rs:WP_008827154	phosphoribosyl-ATP pyrophosphatase [Haloplasma contractile].	45.31	128	62	1	11	130	1	128	9e-34	128
rs:WP_028976349	phosphoribosyl-ATP pyrophosphatase [Sporolactobacillus terrae].	54.00	100	46	0	13	112	1	100	9e-34	128
tr:K9SRA1_9SYNE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	56.86	102	43	1	16	116	13	114	9e-34	125
rs:WP_036958225	phosphoribosyl-AMP cyclohydrolase [Propionibacterium humerusii].	58.95	95	39	0	18	112	19	113	9e-34	125
tr:D6VAI2_9BRAD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	51.35	111	51	1	19	126	5	115	9e-34	125
rs:WP_015450543	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bifidobacterium].	60.00	95	38	0	18	112	26	120	9e-34	125
rs:WP_018842866	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. CNS335].	50.00	114	54	1	2	112	1	114	9e-34	125
rs:WP_027753664	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. CNH099].	57.89	95	40	0	18	112	20	114	9e-34	125
rs:WP_012562785	phosphoribosyl-AMP cyclohydrolase [Oligotropha carboxidovorans].	50.89	112	52	1	19	127	23	134	9e-34	126
sp:HIS3_HERAR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	51.40	107	51	1	16	121	9	115	9e-34	125
rs:WP_033492567	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium thermophilum].	60.00	95	38	0	18	112	26	120	9e-34	125
rs:WP_017336101	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	52.63	114	53	1	18	130	8	121	9e-34	125
rs:WP_035562638	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. 9120].	55.45	101	44	1	18	117	12	112	1e-33	125
rs:WP_002258125	phosphoribosyl-AMP cyclohydrolase [Neisseria meningitidis].	52.59	116	54	1	17	131	8	123	1e-33	125
rs:WP_029634914	phosphoribosyl-AMP cyclohydrolase [actinobacterium SCGC AAA041-L13].	50.48	105	52	0	9	113	2	106	1e-33	125
rs:WP_008443044	phosphoribosyl-AMP cyclohydrolase [Janthinobacterium sp. HH01].	49.15	118	55	2	18	130	17	134	1e-33	126
gpu:CP008874_126	phosphoribosyl-AMP cyclohydrolase [Halanaeroarchaeum sulfurireducens]	56.25	96	42	0	18	113	8	103	1e-33	125
sp:HIS3_AROAE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	47.86	117	59	2	16	130	11	127	1e-33	125
rs:WP_005564095	phosphoribosyl-AMP cyclohydrolase [Rhodococcus wratislaviensis].	57.43	101	43	0	16	116	9	109	1e-33	125
rs:WP_016877292	phosphoribosyl-ATP pyrophosphatase [Chlorogloeopsis fritschii].	57.58	99	41	1	18	115	18	116	1e-33	128
rs:WP_041429716	phosphoribosyl-AMP cyclohydrolase [Synechococcus sp. PCC 7502].	56.86	102	43	1	16	116	6	107	1e-33	125
tr:A0A0D8HP79_9NOCA	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:KJF19753.1};	55.66	106	47	0	16	121	16	121	1e-33	125
rs:WP_047240495	phosphoribosyl-AMP cyclohydrolase [Corynebacterium epidermidicanis].	56.36	110	41	1	18	127	19	121	1e-33	125
tr:B4XNG9_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	49.12	114	57	1	5	117	2	115	1e-33	125
tr:R9CE33_9CLOT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	53.27	107	49	1	11	116	1	107	1e-33	125
rs:WP_041922768	imidazole glycerol phosphate synthase [Cyanobacterium aponinum].	56.57	99	42	1	18	115	18	116	1e-33	128
rs:WP_034770858	phosphoribosyl-ATP pyrophosphatase [Bacillus thermoamylovorans].	52.83	106	50	0	11	116	1	106	1e-33	128
rs:WP_008041892	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. GM67].	52.63	114	53	1	18	130	8	121	1e-33	125
sp:HIS2_SYNY3	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	58.59	99	40	1	18	115	17	115	1e-33	128
rs:WP_028501846	phosphoribosyl-AMP cyclohydrolase [Microbacterium sp. URHA0036].	58.95	95	39	0	18	112	11	105	1e-33	125
rs:WP_045225476	phosphoribosyl-AMP cyclohydrolase [Methylococcaceae bacterium 73a].	50.00	114	56	1	18	130	9	122	1e-33	125
rs:WP_042582951	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. MSHR3999].	50.00	114	56	1	9	121	5	118	1e-33	125
tr:E6QS22_9ZZZZ	SubName: Full=Phosphoribosyl-AMP cyclohydrolase (PRA-CH) {ECO:0000313|EMBL:CBI10044.1}; EC=3.5.4.19 {ECO:0000313|EMBL:CBI10044.1};	50.86	116	56	1	16	130	10	125	1e-33	125
rs:WP_019957556	phosphoribosyl-AMP cyclohydrolase [Vitreoscilla stercoraria].	51.30	115	55	1	18	131	13	127	1e-33	125
rs:WP_027783357	phosphoribosyl-AMP cyclohydrolase [Burkholderia cepacia].	49.12	114	57	1	5	117	2	115	1e-33	125
sp:HIS3_NEIMF	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.04	115	53	1	18	131	9	123	1e-33	125
rs:WP_035307845	phosphoribosyl-AMP cyclohydrolase [Clostridium sp. HMP27].	56.00	100	43	1	14	113	3	101	1e-33	125
sp:HIS3_METB6	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	58.33	96	40	0	18	113	4	99	1e-33	125
rs:WP_005510296	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Corynebacterium].	57.84	102	41	1	19	118	31	132	1e-33	125
tr:D7WEX6_9CORY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.21	113	53	1	1	112	1	113	1e-33	125
rs:WP_019009011	phosphoribosyl-ATP pyrophosphatase [Deinococcus aquatilis].	57.55	106	44	1	14	118	8	113	1e-33	128
sp:HIS2_AQUAE	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	54.46	101	45	1	18	117	4	104	1e-33	127
rs:WP_038615424	phosphoribosyl-AMP cyclohydrolase [Pseudomonas alkylphenolia].	51.75	114	54	1	18	130	8	121	1e-33	125
rs:WP_027723463	phosphoribosyl-AMP cyclohydrolase [Varibaculum cambriense].	56.60	106	42	1	16	121	12	113	1e-33	125
tr:G5IG79_9FIRM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00006950}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	60.20	98	39	0	16	113	257	354	1e-33	132
gpu:CP009502_2062	Phosphoribosyl-AMP cyclohydrolase [Methanosarcina thermophila CHTI-55]	60.19	103	38	2	11	113	28	127	1e-33	125
rs:WP_038625714	phosphoribosyl-AMP cyclohydrolase [Corynebacterium sp. ATCC 6931].	60.64	94	37	0	19	112	31	124	1e-33	125
tr:K7QVP6_THEOS	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	51.40	107	52	0	13	119	2	108	1e-33	127
rs:WP_012163025	phosphoribosyl-ATP pyrophosphatase [Acaryochloris marina].	55.56	108	45	2	9	115	4	109	1e-33	127
rs:WP_045566786	phosphoribosyl-AMP cyclohydrolase [Burkholderia ubonensis].	50.00	114	56	1	9	121	5	118	1e-33	125
rs:WP_034928660	phosphoribosyl-AMP cyclohydrolase [Erysipelotrichaceae bacterium NK3D112].	56.12	98	42	1	24	121	11	107	1e-33	124
rs:WP_029681827	imidazole glycerol phosphate synthase [Synechococcus sp. NKBG15041c].	56.57	99	42	1	18	115	12	110	1e-33	127
tr:L8ACB2_BACIU	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	58.59	99	40	1	18	115	32	130	1e-33	128
rs:WP_033196064	phosphoribosyl-AMP cyclohydrolase [Streptomyces xiaopingdaonensis].	61.05	95	37	0	18	112	19	113	1e-33	125
gpu:CP011503_1509	phosphoribosyl-AMP cyclohydrolase [Burkholderia pyrrocinia]	49.12	114	57	1	5	117	2	115	1e-33	125
rs:WP_044845954	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. USM B20].	49.12	114	57	1	5	117	2	115	1e-33	125
tr:A0A023D1K9_ACIMT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	53.39	118	49	2	18	129	5	122	1e-33	125
rs:WP_045537836	phosphoribosyl-AMP cyclohydrolase, partial [Comamonadaceae bacterium B1].	54.46	101	42	1	17	113	7	107	1e-33	124
rs:WP_025802460	phosphoribosyl-ATP diphosphatase [Campylobacter sp. CIT045].	57.45	94	40	0	24	117	7	100	1e-33	128
rs:WP_016843917	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium elkanii].	51.33	113	55	0	19	131	19	131	1e-33	125
tr:K9Z3W3_CYAAP	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	56.57	99	42	1	18	115	34	132	1e-33	128
rs:WP_013134065	phosphoribosyl-ATP pyrophosphatase [Arcobacter nitrofigilis].	57.45	94	40	0	24	117	14	107	1e-33	128
rs:WP_017903197	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fuscovaginae].	51.75	114	54	1	18	130	8	121	1e-33	125
rs:WP_036289483	phosphoribosyl-AMP cyclohydrolase [Methylosinus sp. PW1].	53.91	115	46	2	19	126	21	135	1e-33	125
rs:WP_034437119	phosphoribosyl-AMP cyclohydrolase [Candidatus Contendobacter odensis].	49.12	114	57	1	18	130	9	122	1e-33	125
rs:WP_008017046	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. GM55].	56.31	103	44	1	18	119	8	110	1e-33	125
rs:WP_044950298	hypothetical protein [Lachnospiraceae bacterium YSB2008].	56.60	106	44	1	9	114	214	317	1e-33	132
rs:WP_028650644	phosphoribosyl-AMP cyclohydrolase [Nocardioides halotolerans].	60.00	95	38	0	18	112	15	109	1e-33	125
rs:WP_032496794	phosphoribosyl-ATP pyrophosphatase [Hydrogenivirga sp. 128-5-R1-1].	53.00	100	47	0	14	113	2	101	1e-33	127
rs:WP_021601574	phosphoribosyl-AMP cyclohydrolase [Actinobaculum sp. oral taxon 183].	57.73	97	40	1	16	112	11	106	1e-33	125
sp:HIS3_RHOJR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	57.43	101	43	0	16	116	9	109	1e-33	124
tr:U1XBE3_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	49.15	118	57	2	1	117	1	116	1e-33	125
rs:WP_019742395	phosphoribosyl-AMP cyclohydrolase [Pseudomonas savastanoi].	51.75	114	54	1	18	130	8	121	1e-33	125
rs:WP_006112640	phosphoribosyl-AMP cyclohydrolase [Halorubrum coriense].	55.00	100	45	0	18	117	13	112	1e-33	125
rs:WP_015752669	phosphoribosyl-AMP cyclohydrolase [Desulfohalobium retbaense].	60.40	101	39	1	24	123	11	111	1e-33	125
rs:WP_022073351	phosphoribosyl-AMP cyclohydrolase [Anaerotruncus sp. CAG:528].	55.56	99	44	0	20	118	11	109	1e-33	124
rs:WP_020467027	phosphoribosyl-AMP cyclohydrolase [Singulisphaera acidiphila].	55.96	109	47	1	16	123	10	118	1e-33	125
rs:WP_013126676	phosphoribosyl-AMP cyclohydrolase [Tsukamurella paurometabola].	61.05	95	37	0	18	112	16	110	1e-33	125
tr:H6WNN4_9ACTN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.00	100	43	0	14	113	6	105	1e-33	124
rs:WP_008362968	phosphoribosyl-AMP cyclohydrolase [Nocardioidaceae bacterium Broad-1].	56.84	95	41	0	18	112	18	112	1e-33	125
rs:WP_024123980	phosphoribosyl-AMP cyclohydrolase [Thermosynechococcus sp. NK55a].	53.27	107	49	1	8	113	3	109	1e-33	127
tr:A0A070CDD1_BURCE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	49.12	114	57	1	5	117	2	115	1e-33	125
rs:WP_006411137	phosphoribosyl-AMP cyclohydrolase [Burkholderia multivorans].	46.03	126	64	2	5	126	2	127	1e-33	125
rs:WP_007989281	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	56.31	103	44	1	18	119	8	110	1e-33	125
rs:WP_010222338	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	51.75	114	54	1	18	130	8	121	1e-33	125
rs:WP_028461383	phosphoribosyl-AMP cyclohydrolase [Nitrosomonas cryotolerans].	47.41	116	60	1	16	130	7	122	1e-33	125
tr:A0A078MNX9_9MICC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	56.70	97	42	0	16	112	29	125	1e-33	125
rs:WP_040688910	phosphoribosyl-AMP cyclohydrolase [Nocardia vinacea].	57.89	95	40	0	18	112	11	105	1e-33	124
tr:A8UZ95_9AQUI	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	53.00	100	47	0	14	113	3	102	1e-33	127
tr:B4XNN2_PSEPY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	49.12	114	57	1	5	117	2	115	1e-33	125
rs:WP_026234163	imidazole glycerol phosphate synthase [Thermus oshimai].	51.40	107	52	0	13	119	1	107	1e-33	127
rs:WP_006882520	phosphoribosyl-AMP cyclohydrolase [Halosimplex carlsbadense].	56.00	100	44	0	18	117	6	105	1e-33	125
rs:WP_022299252	phosphoribosyl-AMP cyclohydrolase [Clostridium sp. CAG:964].	54.81	104	44	1	11	114	1	101	1e-33	124
rs:WP_034424355	phosphoribosyl-ATP pyrophosphatase [Clostridiales bacterium DRI-13].	57.73	97	41	0	16	112	9	105	1e-33	127
rs:WP_015492060	phosphoribosyl-ATP pyrophosphohydrolase [Thermoplasmatales archaeon BRNA1].	56.31	103	45	0	14	116	3	105	1e-33	127
sp:HIS2_THEEB	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	53.27	107	49	1	8	113	3	109	1e-33	127
rs:WP_009020376	phosphoribosyl-AMP cyclohydrolase [Luminiphilus syltensis].	54.72	106	47	1	19	123	16	121	1e-33	125
rs:WP_012169472	phosphoribosyl-AMP cyclohydrolase [Azorhizobium caulinodans].	54.29	105	46	1	19	121	26	130	1e-33	126
rs:WP_024310178	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. P818].	54.05	111	49	1	17	127	24	132	1e-33	125
tr:A0A063ZPQ7_9EURY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	58.51	94	39	0	24	117	13	106	1e-33	125
rs:WP_039458674	imidazole glycerol phosphate synthase [Thermus sp. 2.9].	51.85	108	52	0	13	120	1	108	1e-33	127
rs:WP_011917539	phosphoribosyl-ATP pyrophosphatase [Caldicellulosiruptor saccharolyticus].	47.41	116	61	0	13	128	2	117	1e-33	127
tr:A3ZTQ2_9PLAN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	62.22	90	34	0	24	113	57	146	1e-33	126
rs:WP_006494429	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Burkholderia cepacia complex].	49.12	114	57	1	5	117	2	115	1e-33	125
rs:WP_017573563	phosphoribosyl-AMP cyclohydrolase [Nocardiopsis halotolerans].	58.95	95	39	0	18	112	14	108	1e-33	124
sp:HIS3_RHOPA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.88	104	48	1	19	121	26	129	1e-33	125
rs:WP_025960948	imidazole glycerol phosphate synthase, partial [Prochlorococcus sp. scB245a_519L21].	53.27	107	49	1	12	117	6	112	1e-33	127
tr:F8B5R9_FRADG	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	58.95	95	39	0	18	112	35	129	1e-33	126
sp:HIS3_BURM1	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	46.03	126	64	2	5	126	2	127	1e-33	125
rs:WP_013256925	phosphoribosyl-AMP cyclohydrolase [Desulfarculus baarsii].	60.61	99	38	1	23	120	10	108	1e-33	125
rs:WP_035943621	phosphoribosyl-AMP cyclohydrolase, partial [Frankia sp. Iso899].	60.00	95	38	0	18	112	31	125	1e-33	125
rs:WP_038682281	phosphoribosyl-ATP pyrophosphatase [Rubrobacter radiotolerans].	53.57	112	51	1	9	119	2	113	1e-33	127
rs:WP_034297843	phosphoribosyl-AMP cyclohydrolase [Herbaspirillum sp. RV1423].	50.47	107	52	1	16	121	9	115	1e-33	125
rs:WP_032378995	phosphoribosyl-AMP cyclohydrolase [Rhodococcus fascians].	54.21	107	49	0	15	121	8	114	1e-33	124
gpu:CP009508_832	Phosphoribosyl-AMP cyclohydrolase [Methanosarcina siciliae C2J]	57.01	107	43	2	11	117	2	105	1e-33	125
rs:WP_015144946	phosphoribosyl-AMP cyclohydrolase [Pleurocapsa minor].	58.76	97	39	1	18	113	18	114	1e-33	127
rs:WP_027409921	phosphoribosyl-ATP pyrophosphatase [Anoxybacillus tepidamans].	54.00	100	46	0	13	112	1	100	1e-33	127
rs:WP_029902488	phosphoribosyl-AMP cyclohydrolase [Nocardia brasiliensis].	57.89	95	40	0	18	112	11	105	1e-33	124
rs:WP_035011017	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium adolescentis].	58.95	95	39	0	18	112	20	114	1e-33	125
rs:WP_012398244	phosphoribosyl-AMP cyclohydrolase [Kocuria rhizophila].	58.95	95	39	0	18	112	21	115	1e-33	125
sp:HIS3_DESVH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	61.22	98	37	1	23	119	12	109	1e-33	125
rs:WP_017126934	phosphoribosyl-AMP cyclohydrolase [Pseudomonas gingeri].	51.75	114	54	1	18	130	8	121	1e-33	125
rs:WP_040298689	phosphoribosyl-AMP cyclohydrolase [Afipia sp. 1NLS2].	51.35	111	51	1	19	126	20	130	1e-33	125
tr:F7QQ67_9BRAD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	50.46	109	52	1	19	125	21	129	1e-33	125
rs:WP_005260335	phosphoribosyl-AMP cyclohydrolase [Rhodococcus opacus].	55.66	106	47	0	16	121	9	114	1e-33	124
rs:WP_040388193	phosphoribosyl-ATP pyrophosphatase [Desmospora sp. 8437].	52.78	108	51	0	18	125	4	111	1e-33	127
rs:WP_041848797	phosphoribosyl-ATP pyrophosphatase [Bacillus thermoamylovorans].	51.89	106	51	0	11	116	1	106	1e-33	127
rs:WP_011437406	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Frankia].	57.89	95	40	0	18	112	16	110	1e-33	126
tr:I4E799_NEIME	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	53.04	115	53	1	18	131	9	123	2e-33	125
rs:WP_025280363	phosphoribosyl-AMP cyclohydrolase [Ectothiorhodospira haloalkaliphila].	54.37	103	46	1	18	119	9	111	2e-33	125
rs:WP_040866027	phosphoribosyl-AMP cyclohydrolase [Nocardia exalbida].	57.89	95	40	0	18	112	11	105	2e-33	124
rs:WP_039797256	phosphoribosyl-AMP cyclohydrolase [Nocardia araoensis].	54.81	104	47	0	18	121	11	114	2e-33	124
rs:WP_028997751	phosphoribosyl-AMP cyclohydrolase [Azohydromonas australica].	55.00	100	41	1	18	113	7	106	2e-33	125
rs:WP_031400085	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Burkholderia].	49.12	114	57	1	5	117	2	115	2e-33	125
rs:WP_006485347	phosphoribosyl-AMP cyclohydrolase [Burkholderia cenocepacia].	49.12	114	57	1	5	117	2	115	2e-33	125
rs:WP_034183655	phosphoribosyl-AMP cyclohydrolase [Burkholderia pyrrocinia].	49.56	113	56	1	6	117	3	115	2e-33	125
tr:X1E705_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_S09362 {ECO:0000313|EMBL:GAH04438.1}; Flags: Fragment;	50.93	108	52	1	19	125	19	126	2e-33	125
rs:WP_006406978	phosphoribosyl-AMP cyclohydrolase [Burkholderia multivorans].	46.03	126	64	2	5	126	2	127	2e-33	125
rs:WP_028462842	phosphoribosyl-AMP cyclohydrolase [Nocardia sp. 348MFTsu5.1].	60.00	95	38	0	18	112	11	105	2e-33	124
rs:WP_046816940	phosphoribosyl-AMP cyclohydrolase [Pseudomonas putida].	56.31	103	44	1	18	119	8	110	2e-33	125
rs:WP_047312874	phosphoribosyl-AMP cyclohydrolase, partial [Dermacoccus sp. PE3].	57.89	95	40	0	18	112	17	111	2e-33	124
rs:WP_029525933	phosphoribosyl-AMP cyclohydrolase [Polaromonas glacialis].	50.47	107	49	1	17	119	6	112	2e-33	125
rs:WP_024011255	phosphoribosyl-AMP cyclohydrolase [Pseudomonas moraviensis].	52.63	114	53	1	18	130	8	121	2e-33	125
rs:WP_018155736	hypothetical protein [Demetria terragena].	52.68	112	53	0	2	113	1	112	2e-33	124
rs:WP_015093121	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. UW4].	56.31	103	44	1	18	119	8	110	2e-33	125
rs:WP_036861609	phosphoribosyl-AMP cyclohydrolase [Porticoccus hydrocarbonoclasticus].	49.12	114	57	1	18	130	8	121	2e-33	125
rs:WP_010548161	phosphoribosyl-AMP cyclohydrolase [gamma proteobacterium HIMB30].	56.84	95	41	0	18	112	17	111	2e-33	125
rs:WP_027020935	phosphoribosyl-AMP cyclohydrolase [Corynebacterium sputi].	57.89	95	40	0	18	112	18	112	2e-33	124
rs:WP_017743246	phosphoribosyl-ATP pyrophosphatase [Scytonema hofmanni].	56.00	100	43	1	17	115	17	116	2e-33	127
sp:HIS3_CHLCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	49.57	115	57	1	17	130	14	128	2e-33	125
rs:WP_027180628	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio desulfuricans].	59.00	100	40	1	24	122	14	113	2e-33	125
rs:WP_041059484	phosphoribosyl-ATP pyrophosphatase [Cohnella sp. VKM B-2846].	51.40	107	52	0	18	124	13	119	2e-33	127
rs:WP_043924323	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobiaceae bacterium SG-6C].	50.46	109	52	1	19	125	27	135	2e-33	125
rs:WP_038997556	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	51.75	114	54	1	18	130	8	121	2e-33	125
rs:WP_002233655	phosphoribosyl-AMP cyclohydrolase [Neisseria meningitidis].	51.72	116	55	1	17	131	8	123	2e-33	125
rs:WP_026502932	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium boum].	60.00	95	38	0	18	112	26	120	2e-33	125
rs:WP_017187685	hypothetical protein [Alkalibacillus haloalkaliphilus].	54.00	100	46	0	18	117	6	105	2e-33	127
rs:WP_015126097	phosphoribosyl-AMP cyclohydrolase [Synechococcus sp. PCC 6312].	58.00	100	41	1	17	115	10	109	2e-33	127
rs:WP_038383245	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium elkanii].	54.21	107	49	0	19	125	19	125	2e-33	125
rs:WP_015389940	phosphoribosyl-AMP cyclohydrolase [Kinetoplastibacterium blastocrithidii].	51.92	104	49	1	16	118	10	113	2e-33	125
rs:WP_008115838	phosphoribosyl-AMP cyclohydrolase [Herbaspirillum sp. YR522].	50.94	106	51	1	16	120	9	114	2e-33	125
rs:WP_023950621	phosphoribosyl-AMP cyclohydrolase [Microbacterium sp. TS-1].	55.34	103	46	0	10	112	4	106	2e-33	124
rs:WP_040733640	phosphoribosyl-AMP cyclohydrolase [Nocardia tenerifensis].	58.95	95	39	0	18	112	11	105	2e-33	124
rs:WP_042623680	phosphoribosyl-AMP cyclohydrolase [Burkholderia glumae].	53.33	105	48	1	18	121	16	120	2e-33	125
rs:WP_017984011	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Amycolatopsis].	56.48	108	42	1	18	125	11	113	2e-33	124
rs:WP_041050368	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. VKM B-2647].	52.29	109	50	1	15	121	5	113	2e-33	128
gp:CP003733_183	phosphoribosyl-AMP cyclohydrolase [Candidatus Kinetoplastibacterium blastocrithidii (ex Strigomonas]	51.92	104	49	1	16	118	9	112	2e-33	125
rs:WP_044279882	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium thermophilum].	60.00	95	38	0	18	112	26	120	2e-33	125
rs:WP_035506623	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. MP-1].	53.33	105	48	1	18	121	11	115	2e-33	125
rs:WP_022369915	phosphoribosyl-AMP cyclohydrolase [Eggerthella sp. CAG:368].	57.00	100	43	0	14	113	2	101	2e-33	124
rs:WP_022206008	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [Eubacterium sp. CAG:252].	59.38	96	39	0	18	113	259	354	2e-33	130
rs:WP_034189813	phosphoribosyl-AMP cyclohydrolase [Burkholderia cenocepacia].	49.12	114	57	1	5	117	2	115	2e-33	125
rs:WP_015311004	phosphoribosyl-AMP cyclohydrolase [Thermoanaerobacterium thermosaccharolyticum].	57.29	96	41	0	18	113	6	101	2e-33	127
rs:WP_044963141	imidazole glycerol phosphate synthase [Eubacterium ramulus].	53.21	109	49	1	25	131	1	109	2e-33	126
rs:WP_033107058	phosphoribosyl-AMP cyclohydrolase [Microbacterium profundi].	58.95	95	39	0	18	112	11	105	2e-33	124
rs:WP_021960884	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [Butyrivibrio crossotus CAG:259].	57.58	99	42	0	16	114	247	345	2e-33	130
rs:WP_021762520	phosphoribosyl-AMP cyclohydrolase [Leifsonia aquatica].	61.05	95	37	0	18	112	12	106	2e-33	125
rs:WP_005600766	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [Butyrivibrio crossotus].	57.58	99	42	0	16	114	247	345	2e-33	130
rs:WP_022450738	phosphoribosyl-ATP diphosphatase [Roseburia sp. CAG:303].	53.85	117	52	1	16	130	193	309	2e-33	131
rs:WP_005247504	phosphoribosyl-AMP cyclohydrolase [Rhodococcus opacus].	55.66	106	47	0	16	121	9	114	2e-33	124
rs:WP_018272284	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium elkanii].	51.33	113	55	0	19	131	19	131	2e-33	125
rs:WP_018929161	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	52.63	114	53	1	18	130	8	121	2e-33	125
rs:WP_019508177	phosphoribosyl-ATP pyrophosphatase [Pleurocapsa sp. PCC 7319].	56.57	99	42	1	18	115	16	114	2e-33	127
rs:WP_014312104	phosphoribosyl-ATP pyrophosphatase [Clostridium sp. BNL1100].	44.63	121	61	1	16	130	6	126	2e-33	127
rs:WP_041123178	phosphoribosyl-ATP pyrophosphatase [Jeotgalibacillus alimentarius].	48.21	112	58	0	11	122	1	112	2e-33	127
rs:WP_046031191	phosphoribosyl-AMP cyclohydrolase [Pseudomonas fluorescens].	56.31	103	44	1	18	119	8	110	2e-33	125
sp:HIS3_RHOOB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	57.73	97	41	0	16	112	9	105	2e-33	124
rs:WP_008344142	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Burkholderia].	53.33	105	48	1	18	121	11	115	2e-33	125
rs:WP_013560761	phosphoribosyl-AMP cyclohydrolase [Anaerolinea thermophila].	55.00	100	45	0	18	117	4	103	2e-33	124
rs:WP_009367271	phosphoribosyl-AMP cyclohydrolase [Halogranum salarium].	55.14	107	47	1	15	121	2	107	2e-33	124
rs:WP_024423556	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillus].	53.21	109	48	1	16	124	5	110	2e-33	127
rs:WP_010037700	phosphoribosyl-AMP cyclohydrolase [Gemmata obscuriglobus].	55.96	109	45	3	15	121	2	109	2e-33	124
rs:WP_004269090	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium animalis].	58.95	95	39	0	18	112	23	117	2e-33	125
rs:WP_015161235	phosphoribosyl-ATP pyrophosphohydrolase [Chamaesiphon minutus].	55.56	99	43	1	18	115	18	116	2e-33	127
rs:WP_027141289	phosphoribosyl-AMP cyclohydrolase [Frankia sp. CN3].	58.95	95	39	0	18	112	16	110	2e-33	125
rs:WP_041432046	phosphoribosyl-AMP cyclohydrolase [Thermobispora bispora].	57.89	95	40	0	18	112	11	105	2e-33	124
rs:WP_021883057	phosphoribosyl-AMP cyclohydrolase [Ruminococcus sp. CAG:108].	54.37	103	44	1	11	113	1	100	2e-33	124
rs:WP_038209575	phosphoribosyl-AMP cyclohydrolase [Xenophilus azovorans].	48.72	117	56	1	18	130	7	123	2e-33	124
rs:WP_026543676	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. 35/47].	52.68	112	52	1	2	112	10	121	2e-33	125
tr:S2F6P8_9PSED	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	56.31	103	44	1	18	119	14	116	2e-33	125
rs:WP_013235991	phosphoribosyl-AMP cyclohydrolase [Herbaspirillum seropedicae].	48.70	115	55	2	16	126	9	123	2e-33	125
rs:WP_040050412	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. MR1].	53.33	105	48	1	18	121	11	115	2e-33	125
rs:WP_041039763	imidazole glycerol phosphate synthase [Tolypothrix campylonemoides].	57.43	101	42	1	18	117	18	118	2e-33	127
rs:WP_002924110	phosphoribosyl-AMP cyclohydrolase [Thauera sp. 28].	54.13	109	50	0	10	118	15	123	2e-33	125
rs:WP_012739256	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [[Eubacterium] eligens].	56.86	102	44	0	12	113	253	354	2e-33	130
rs:WP_037107678	phosphoribosyl-AMP cyclohydrolase [Rhodococcus fascians].	56.84	95	41	0	18	112	11	105	2e-33	124
rs:WP_037809655	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Actinomycetales].	58.00	100	42	0	15	114	8	107	2e-33	124
rs:WP_015395990	phosphoribosyl-AMP cyclohydrolase [Candidatus Kinetoplastibacterium desouzaii].	55.10	98	43	1	17	113	14	111	2e-33	125
sp:HIS2_DEIRA	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	53.51	114	52	1	14	126	3	116	2e-33	127
tr:W0K5V9_9EURY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	57.28	103	42	2	11	113	1	101	2e-33	124
rs:WP_022465456	phosphoribosyl-ATP diphosphatase [Clostridium sp. CAG:277].	60.00	100	40	0	14	113	217	316	2e-33	131
rs:WP_006461578	phosphoribosyl-AMP cyclohydrolase [Herbaspirillum frisingense].	48.70	115	55	2	16	126	9	123	2e-33	125
rs:WP_020265161	hypothetical protein [Atribacteria bacterium JGI 0000059-I14].	49.53	107	54	0	18	124	11	117	2e-33	127
rs:WP_039764372	imidazole glycerol phosphate synthase [Caldicellulosiruptor sp. F32].	46.55	116	62	0	13	128	2	117	2e-33	127
rs:WP_005002676	phosphoribosyl-AMP cyclohydrolase [Nitrococcus mobilis].	51.75	114	54	1	18	130	9	122	2e-33	124
rs:WP_040385281	phosphoribosyl-AMP cyclohydrolase, partial [Citricoccus sp. CH26A].	60.00	95	38	0	18	112	15	109	2e-33	124
rs:WP_010595268	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Rhodococcus].	60.00	95	38	0	18	112	12	106	2e-33	124
rs:WP_013485326	phosphoribosyl-AMP cyclohydrolase [Ethanoligenens harbinense].	56.70	97	42	0	20	116	7	103	2e-33	124
rs:WP_036901132	imidazole glycerol phosphate synthase [Prochlorococcus sp. MIT 0601].	53.77	106	47	2	9	113	4	108	2e-33	127
rs:WP_023022973	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Corynebacterium].	61.05	95	36	1	18	112	17	110	2e-33	124
rs:WP_024427673	phosphoribosyl-ATP pyrophosphatase [Bacillus pumilus].	53.21	109	48	1	16	124	5	110	2e-33	127
rs:WP_044331215	phosphoribosyl-AMP cyclohydrolase [Sphingomonas sp. WHSC-8].	55.88	102	44	1	19	120	14	114	2e-33	124
rs:WP_034753847	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Janthinobacterium].	48.31	118	56	2	18	130	17	134	2e-33	125
rs:WP_016346401	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. RPE64].	53.33	105	48	1	18	121	11	115	2e-33	124
rs:WP_015651629	phosphoribosyl-AMP cyclohydrolase [Corynebacterium callunae].	58.95	95	39	0	18	112	18	112	2e-33	124
rs:WP_028477533	phosphoribosyl-AMP cyclohydrolase [Nocardia sp. CNY236].	57.89	95	40	0	18	112	11	105	2e-33	124
rs:WP_009691883	phosphoribosyl-AMP cyclohydrolase [Burkholderia cenocepacia].	47.93	121	60	2	2	121	1	119	2e-33	125
rs:WP_013696438	phosphoribosyl-AMP cyclohydrolase [Burkholderia gladioli].	45.90	122	65	1	1	121	1	122	2e-33	125
rs:WP_040532160	hypothetical protein [Lautropia mirabilis].	55.34	103	45	1	18	119	1	103	2e-33	125
rs:WP_029389078	phosphoribosyl-AMP cyclohydrolase [SAR324 cluster bacterium SCGC AAA001-C10].	54.37	103	41	2	11	113	6	102	2e-33	124
rs:WP_046904733	phosphoribosyl-AMP cyclohydrolase [Altererythrobacter atlanticus].	46.40	125	64	2	1	124	1	123	2e-33	124
tr:A0A096LGQ4_9ACTN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	56.44	101	44	0	13	113	5	105	2e-33	124
rs:WP_003796303	phosphoribosyl-AMP cyclohydrolase [Kingella oralis].	49.59	123	61	1	10	131	4	126	2e-33	124
rs:WP_025435687	hypothetical protein [Eubacterium acidaminophilum].	49.11	112	56	1	18	128	8	119	2e-33	127
tr:D3R4Y0_BIFAB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	58.95	95	39	0	18	112	32	126	2e-33	125
tr:W8TFV5_EUBAC	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	49.11	112	56	1	18	128	7	118	2e-33	127
rs:WP_006092917	phosphoribosyl-AMP cyclohydrolase [Natronorubrum tibetense].	55.00	100	45	0	18	117	10	109	2e-33	124
rs:WP_042256056	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Nocardia].	57.58	99	42	0	18	116	11	109	2e-33	124
rs:WP_033045332	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudomonas].	56.31	103	44	1	18	119	8	110	2e-33	124
rs:WP_029226624	phosphoribosyl-AMP cyclohydrolase [Burkholderia ubonensis].	46.72	122	61	2	9	126	5	126	2e-33	125
tr:L0DNC0_SINAD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	55.96	109	47	1	16	123	33	141	2e-33	125
rs:WP_012306119	phosphoribosyl-ATP pyrophosphatase [Synechococcus sp. PCC 7002].	56.57	99	42	1	18	115	12	110	2e-33	127
rs:WP_012302704	phosphoribosyl-ATP pyrophosphatase [Candidatus Desulforudis audaxviator].	55.34	103	46	0	11	113	1	103	2e-33	127
sp:HIS3_NITHX	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.73	110	49	1	19	125	21	130	2e-33	125
rs:WP_015794302	phosphoribosyl-AMP cyclohydrolase [Catenulispora acidiphila].	61.05	95	37	0	18	112	18	112	2e-33	125
rs:WP_025906509	MULTISPECIES: imidazole glycerol phosphate synthase [Prochlorococcus].	51.38	109	52	1	10	117	4	112	2e-33	127
rs:WP_013883854	phosphoribosyl-AMP cyclohydrolase [[Cellvibrio] gilvus].	58.76	97	40	0	16	112	10	106	2e-33	124
rs:WP_020077502	phosphoribosyl-AMP cyclohydrolase [Cryocola sp. 340MFSha3.1].	58.95	95	39	0	18	112	13	107	2e-33	124
rs:WP_035137859	phosphoribosyl-AMP cyclohydrolase [Collinsella sp. 4_8_47FAA].	57.00	100	43	0	14	113	2	101	2e-33	124
rs:WP_017575489	phosphoribosyl-AMP cyclohydrolase [Nocardiopsis kunsanensis].	58.95	95	39	0	18	112	14	108	2e-33	124
rs:WP_042924398	phosphoribosyl-AMP cyclohydrolase [Kingella kingae].	49.18	122	61	1	11	131	1	122	2e-33	124
rs:WP_040807197	phosphoribosyl-AMP cyclohydrolase [Nocardia concava].	58.59	99	41	0	18	116	12	110	2e-33	124
tr:A0A060NQY1_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.46	101	42	1	17	113	7	107	2e-33	125
rs:WP_006065932	phosphoribosyl-AMP cyclohydrolase [Natronorubrum bangense].	51.89	106	51	0	12	117	4	109	2e-33	124
rs:WP_022076423	histidine biosynthesis bifunctional protein HisIE [Firmicutes bacterium CAG:212].	55.36	112	48	1	2	113	215	324	2e-33	131
rs:WP_043633937	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio sp. TomC].	58.42	101	41	1	23	122	10	110	2e-33	124
rs:WP_007975565	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. GM33].	56.31	103	44	1	18	119	8	110	2e-33	124
rs:WP_041777118	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium animalis].	58.95	95	39	0	18	112	23	117	2e-33	124
rs:WP_022184455	phosphoribosyl-AMP cyclohydrolase [Eggerthella sp. CAG:209].	59.38	96	39	0	18	113	14	109	2e-33	124
rs:WP_018191187	phosphoribosyl-AMP cyclohydrolase [Leifsonia sp. 109].	58.95	95	39	0	18	112	13	107	2e-33	124
rs:WP_026863522	phosphoribosyl-AMP cyclohydrolase [Intrasporangiaceae bacterium URHB0013].	60.00	95	38	0	18	112	22	116	2e-33	125
rs:WP_015504380	phosphoribosyl-AMP cyclohydrolase [Candidatus Methanomethylophilus alvus].	54.37	103	47	0	14	116	3	105	2e-33	126
rs:WP_036340787	phosphoribosyl-AMP cyclohydrolase [Modestobacter sp. KNN45-2b].	52.21	113	53	1	2	113	1	113	2e-33	124
rs:WP_016294380	phosphoribosyl-ATP diphosphatase [Lachnospiraceae bacterium M18-1].	57.14	105	43	1	9	113	222	324	2e-33	131
rs:WP_021005893	phosphoribosyl-AMP cyclohydrolase [Variovorax paradoxus].	47.86	117	57	1	18	130	7	123	2e-33	124
rs:WP_036048472	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Burkholderia].	45.90	122	65	1	1	121	1	122	2e-33	125
rs:WP_040673891	phosphoribosyl-AMP cyclohydrolase [Nitrobacter sp. Nb-311A].	54.46	101	46	0	19	119	19	119	2e-33	125
tr:A3WVN7_9BRAD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.46	101	46	0	19	119	5	105	2e-33	124
rs:WP_041522272	phosphoribosyl-AMP cyclohydrolase [Gilvimarinus agarilyticus].	49.57	115	57	1	18	131	12	126	2e-33	124
rs:WP_017587257	phosphoribosyl-AMP cyclohydrolase [Nocardiopsis ganjiahuensis].	60.00	95	38	0	18	112	14	108	3e-33	124
rs:WP_043558003	phosphoribosyl-AMP cyclohydrolase [Actinomyces israelii].	59.18	98	40	0	15	112	8	105	3e-33	124
sp:HIS3_RHOPT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.88	104	48	1	19	121	26	129	3e-33	125
tr:B4XN52_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	49.12	114	57	1	5	117	2	115	3e-33	124
rs:WP_036296240	phosphoribosyl-AMP cyclohydrolase [Microbacterium sp. C448].	50.89	112	55	0	1	112	1	112	3e-33	124
rs:WP_040770804	phosphoribosyl-AMP cyclohydrolase, partial [Rhodopirellula maiorica].	57.00	100	41	1	19	116	3	102	3e-33	124
rs:WP_031937981	phosphoribosyl-AMP cyclohydrolase [Rhodococcus defluvii].	56.73	104	45	0	18	121	11	114	3e-33	124
rs:WP_039793710	phosphoribosyl-ATP pyrophosphatase [Paenibacillus elgii].	56.31	103	45	0	15	117	5	107	3e-33	127
rs:WP_046581239	phosphoribosyl-AMP cyclohydrolase [Burkholderia gladioli].	45.90	122	65	1	1	121	1	122	3e-33	125
rs:WP_025928212	imidazole glycerol phosphate synthase [Prochlorococcus sp. scB243_495G23].	53.27	107	49	1	12	117	6	112	3e-33	127
rs:WP_046426790	phosphoribosyl-AMP cyclohydrolase [Burkholderia vietnamiensis].	52.38	105	49	1	18	121	15	119	3e-33	124
tr:A0A0B6W022_9BIFI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	58.95	95	39	0	18	112	32	126	3e-33	125
rs:WP_017833956	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Kocuria].	53.91	115	49	2	2	112	1	115	3e-33	124
rs:WP_017453777	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Herbaspirillum].	48.70	115	55	2	16	126	9	123	3e-33	125
rs:WP_040143131	phosphoribosyl-AMP cyclohydrolase [Burkholderia cenocepacia].	49.12	114	57	1	5	117	2	115	3e-33	124
rs:WP_025887895	MULTISPECIES: imidazole glycerol phosphate synthase [Prochlorococcus].	53.27	107	49	1	12	117	6	112	3e-33	127
rs:WP_022542778	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium animalis].	58.95	95	39	0	18	112	23	117	3e-33	124
tr:A0A086ZZ17_9BIFI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.05	111	42	1	11	112	1	111	3e-33	125
rs:WP_026195213	phosphoribosyl-AMP cyclohydrolase [Gallionella sp. SCGC AAA018-N21].	52.83	106	49	1	16	120	5	110	3e-33	124
rs:WP_028312390	phosphoribosyl-AMP cyclohydrolase [Derxia gummosa].	52.43	103	48	1	18	119	20	122	3e-33	125
rs:WP_008105446	phosphoribosyl-AMP cyclohydrolase [Verrucomicrobiae bacterium DG1235].	50.44	113	48	2	19	123	24	136	3e-33	125
rs:WP_028342684	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium elkanii].	54.21	107	49	0	19	125	19	125	3e-33	124
tr:K1T029_9ZZZZ	SubName: Full=Phosphoribosyl-ATP diphosphatase {ECO:0000313|EMBL:EKC61014.1}; Flags: Fragment;	54.37	103	47	0	14	116	6	108	3e-33	127
rs:WP_025945090	imidazole glycerol phosphate synthase [Prochlorococcus sp. scB241_528K19].	53.27	107	49	1	12	117	6	112	3e-33	127
rs:WP_017132778	phosphoribosyl-AMP cyclohydrolase [Pseudomonas agarici].	50.00	114	56	1	18	130	8	121	3e-33	124
rs:WP_039783855	phosphoribosyl-AMP cyclohydrolase [Herbaspirillum huttiense].	48.70	115	55	2	16	126	9	123	3e-33	125
tr:C0W3B0_9ACTO	RecName: Full=Imidazole glycerol phosphate synthase subunit hisF {ECO:0000256|RuleBase:RU003659}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216}; EC=4.1.3.- {ECO:0000256|RuleBase:RU003659, ECO:0000256|SAAS:SAAS00088643};	62.11	95	36	0	18	112	273	367	3e-33	130
rs:WP_029929113	phosphoribosyl-AMP cyclohydrolase [Nocardia otitidiscaviarum].	57.89	95	40	0	18	112	11	105	3e-33	124
sp:HIS3_BURVG	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.38	105	49	1	18	121	15	119	3e-33	124
rs:WP_032746977	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium longum].	59.79	97	39	0	16	112	18	114	3e-33	124
rs:WP_028249250	phosphoribosyl-AMP cyclohydrolase [Variovorax sp. URHB0020].	48.72	117	56	1	18	130	7	123	3e-33	124
rs:WP_035930916	phosphoribosyl-AMP cyclohydrolase [Burkholderia glathei].	52.38	105	49	1	18	121	11	115	3e-33	124
rs:WP_044910472	hypothetical protein [Lachnospiraceae bacterium MC2017].	58.16	98	41	0	16	113	241	338	3e-33	131
rs:WP_036692574	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. MSt1].	52.10	119	56	1	2	120	1	118	3e-33	127
rs:WP_036897620	imidazole glycerol phosphate synthase [Prochlorococcus marinus].	50.88	114	55	1	9	121	3	116	3e-33	127
rs:WP_013539725	phosphoribosyl-AMP cyclohydrolase [Variovorax paradoxus].	47.86	117	57	1	18	130	7	123	3e-33	124
rs:WP_025913528	MULTISPECIES: imidazole glycerol phosphate synthase [Prochlorococcus].	53.27	107	49	1	12	117	6	112	3e-33	127
rs:WP_034229426	hypothetical protein, partial [Actinotalea ferrariae].	58.95	95	39	0	18	112	25	119	3e-33	124
rs:WP_030528320	phosphoribosyl-AMP cyclohydrolase [Phycicoccus jejuensis].	57.14	98	42	0	15	112	12	109	3e-33	124
rs:WP_005332826	imidazole glycerol phosphate synthase [Dorea formicigenerans].	55.36	112	48	1	2	113	216	325	3e-33	130
rs:WP_023021253	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Corynebacterium].	58.95	95	38	1	18	112	17	110	3e-33	124
rs:WP_025925120	MULTISPECIES: imidazole glycerol phosphate synthase [Prochlorococcus].	53.27	107	49	1	12	117	6	112	3e-33	127
rs:WP_025892983	MULTISPECIES: imidazole glycerol phosphate synthase [Prochlorococcus].	53.27	107	49	1	12	117	6	112	3e-33	127
rs:WP_019665862	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Rhodococcus].	56.84	95	41	0	18	112	11	105	3e-33	124
rs:WP_022965408	phosphoribosyl-AMP cyclohydrolase [Pseudomonas caeni].	53.40	103	47	1	18	119	8	110	3e-33	124
rs:WP_022532827	phosphoribosyl-ATP diphosphatase [Methanoculleus sp. CAG:1088].	56.57	99	43	0	18	116	7	105	3e-33	126
tr:C2GXH4_BIFLN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	59.79	97	39	0	16	112	26	122	3e-33	124
rs:WP_047262422	phosphoribosyl-AMP cyclohydrolase [Corynebacterium mustelae].	58.95	95	39	0	18	112	21	115	3e-33	124
rs:WP_036226983	phosphoribosyl-AMP cyclohydrolase, partial [Marmoricola sp. URHB0036].	56.84	95	41	0	18	112	16	110	3e-33	124
rs:WP_013297103	phosphoribosyl-ATP pyrophosphatase [Thermoanaerobacterium thermosaccharolyticum].	57.29	96	41	0	18	113	6	101	3e-33	127
rs:WP_015236850	phosphoribosyl-ATP pyrophosphohydrolase [Deinococcus peraridilitoris].	54.29	105	46	1	9	113	2	104	3e-33	127
rs:WP_002939373	phosphoribosyl-AMP cyclohydrolase [Thauera sp. 27].	52.59	116	53	1	10	125	15	128	3e-33	124
rs:WP_043473375	phosphoribosyl-AMP cyclohydrolase [Streptomyces fradiae].	57.89	95	40	0	18	112	28	122	3e-33	124
rs:WP_021866716	hypothetical protein [Eubacterium sp. CAG:86].	59.18	98	40	0	16	113	223	320	3e-33	130
rs:WP_044493503	phosphoribosyl-AMP cyclohydrolase [Nesterenkonia sp. NP1].	57.94	107	42	1	18	121	14	120	3e-33	124
rs:WP_040420771	phosphoribosyl-AMP cyclohydrolase [Corynebacterium timonense].	60.00	95	38	0	18	112	18	112	3e-33	124
sp:HIS3_LEPCP	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	49.57	117	55	1	18	130	7	123	3e-33	124
tr:U2CEB1_BIFBI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	53.10	113	44	1	9	112	13	125	3e-33	124
tr:E4HNS7_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	58.95	95	39	0	18	112	51	145	3e-33	125
rs:WP_028708572	phosphoribosyl-AMP cyclohydrolase [Propionicicella superfundia].	56.07	107	45	1	15	119	16	122	3e-33	124
rs:WP_040856836	phosphoribosyl-AMP cyclohydrolase [Nocardia niigatensis].	58.59	99	41	0	18	116	12	110	3e-33	124
rs:WP_009146402	phosphoribosyl-ATP pyrophosphatase [Phascolarctobacterium succinatutens].	53.85	104	48	0	11	114	1	104	3e-33	126
rs:WP_022365950	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [Firmicutes bacterium CAG:341].	55.10	98	44	0	20	117	8	105	3e-33	123
rs:WP_021473060	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. AK-YN10].	58.16	98	41	0	15	112	28	125	3e-33	124
rs:WP_021719141	phosphoribosyl-ATP diphosphatase [Phascolarctobacterium succinatutens].	53.85	104	48	0	11	114	1	104	3e-33	126
sp:HIS3_RHOPS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.00	110	52	1	19	125	23	132	3e-33	124
rs:WP_018657217	phosphoribosyl-AMP cyclohydrolase [Actinomadura flavalba].	57.89	95	40	0	18	112	16	110	3e-33	124
rs:WP_026119964	phosphoribosyl-AMP cyclohydrolase [Nocardiopsis potens].	52.25	111	52	1	3	112	8	118	3e-33	124
rs:WP_033228126	phosphoribosyl-AMP cyclohydrolase, partial [Nesterenkonia sp. F].	58.95	95	39	0	18	112	14	108	3e-33	124
rs:WP_040495992	phosphoribosyl-AMP cyclohydrolase [Ilumatobacter nonamiensis].	53.98	113	51	1	2	113	1	113	3e-33	124
rs:WP_028952392	imidazole glycerol phosphate synthase [Synechococcus sp. CC9616].	60.82	97	37	1	18	113	12	108	3e-33	127
rs:WP_017565141	phosphoribosyl-AMP cyclohydrolase [Nocardiopsis synnemataformans].	54.29	105	47	1	9	112	4	108	3e-33	124
rs:WP_041846322	phosphoribosyl-ATP pyrophosphatase [Bacillus thermoamylovorans].	51.89	106	51	0	11	116	1	106	3e-33	127
rs:WP_007602631	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. WSM1253].	53.21	109	49	1	19	125	17	125	3e-33	124
rs:WP_035399343	phosphoribosyl-AMP cyclohydrolase [Chlorobium sp. GBChlB].	48.28	116	59	1	2	117	1	115	3e-33	124
rs:WP_027771239	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. CNQ329].	55.79	95	42	0	18	112	20	114	3e-33	124
tr:A0A024EB62_9PSED	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	50.88	114	55	1	18	130	17	130	3e-33	124
rs:WP_029253324	phosphoribosyl-AMP cyclohydrolase [Paraoerskovia marina].	55.77	104	46	0	9	112	4	107	3e-33	124
rs:WP_022009946	hypothetical protein [Firmicutes bacterium CAG:646].	59.79	97	39	0	18	114	229	325	3e-33	130
rs:WP_013363516	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium bifidum].	53.10	113	44	1	9	112	9	121	3e-33	124
rs:WP_003819257	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bifidobacterium].	53.10	113	44	1	9	112	6	118	3e-33	124
rs:WP_008367988	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. M47T1].	51.75	114	54	1	18	130	8	121	3e-33	124
rs:WP_036959324	phosphoribosyl-AMP cyclohydrolase [Promicromonospora kroppenstedtii].	51.28	117	57	0	15	131	10	126	3e-33	124
rs:WP_043690547	imidazole glycerol phosphate synthase [Synechococcus sp. KORDI-49].	59.60	99	39	1	16	113	10	108	4e-33	127
rs:WP_040705963	phosphoribosyl-AMP cyclohydrolase [Nocardia takedensis].	58.59	99	41	0	18	116	11	109	4e-33	124
rs:WP_006936996	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Rhodococcus].	60.00	95	38	0	18	112	12	106	4e-33	124
rs:WP_039396763	phosphoribosyl-AMP cyclohydrolase [Microbacterium mangrovi].	57.14	98	42	0	18	115	19	116	4e-33	124
rs:WP_021027782	phosphoribosyl-AMP cyclohydrolase [Comamonas sp. B-9].	48.72	117	56	1	18	130	7	123	4e-33	124
tr:A0A021VLG5_9CELL	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.14	98	42	0	15	112	22	119	4e-33	125
rs:WP_022432115	hypothetical protein [Eubacterium sp. CAG:38].	50.00	140	59	3	2	130	203	342	4e-33	130
rs:WP_005336296	imidazole glycerol phosphate synthase [Dorea formicigenerans CAG:28].	55.36	112	48	1	2	113	218	327	4e-33	130
rs:WP_022356513	phosphoribosyl-AMP cyclohydrolase [Faecalitalea cylindroides].	55.32	94	42	0	24	117	11	104	4e-33	123
rs:WP_002259621	phosphoribosyl-AMP cyclohydrolase [Neisseria meningitidis].	51.72	116	55	1	17	131	8	123	4e-33	124
rs:WP_014983291	phosphoribosyl-AMP cyclohydrolase [Nocardia brasiliensis].	57.89	95	40	0	18	112	11	105	4e-33	123
rs:WP_047012711	phosphoribosyl-AMP cyclohydrolase [Spongiibacter sp. IMCC21906].	52.63	114	53	1	18	130	13	126	4e-33	124
rs:WP_017608000	phosphoribosyl-AMP cyclohydrolase [Nocardiopsis xinjiangensis].	58.95	95	39	0	18	112	14	108	4e-33	123
rs:WP_027422830	hypothetical protein [Lachnospiraceae bacterium AC3007].	60.42	96	38	0	18	113	240	335	4e-33	130
rs:WP_045169380	imidazole glycerol phosphate synthase [Caldicellulosiruptor sp. Rt8.B8].	52.94	102	48	0	13	114	2	103	4e-33	126
rs:WP_036033532	phosphoribosyl-AMP cyclohydrolase [Burkholderia gladioli].	51.43	105	50	1	18	121	18	122	4e-33	124
rs:WP_033493799	phosphoribosyl-AMP cyclohydrolase, partial [Bifidobacterium biavatii].	54.05	111	42	1	11	112	1	111	4e-33	124
rs:WP_029215324	imidazole glycerol phosphate synthase [bacterium JKG1].	60.42	96	38	0	18	113	2	97	4e-33	126
rs:WP_003813324	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium bifidum].	53.10	113	44	1	9	112	6	118	4e-33	124
rs:WP_043198313	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. URHA0002].	51.38	109	51	1	19	125	21	129	4e-33	124
tr:H5SAW0_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	58.16	98	40	1	17	113	3	100	4e-33	126
tr:A0A0D6CHW2_BIFBI	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:BAQ98254.1};	53.10	113	44	1	9	112	9	121	4e-33	124
rs:WP_028129062	phosphoribosyl-ATP pyrophosphatase [Selenomonas sp. AE3005].	54.37	103	46	1	10	112	2	103	4e-33	127
rs:WP_007611749	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. WSM471].	53.21	109	49	1	19	125	17	125	4e-33	124
rs:WP_003670703	phosphoribosyl-AMP cyclohydrolase [Moraxella catarrhalis].	53.45	116	52	2	17	130	10	125	4e-33	127
rs:WP_003661129	phosphoribosyl-AMP cyclohydrolase [Moraxella catarrhalis].	53.45	116	52	2	17	130	10	125	4e-33	127
rs:WP_015590612	phosphoribosyl-AMP cyclohydrolase [Archaeoglobus sulfaticallidus].	50.00	104	52	0	11	114	6	109	4e-33	123
rs:WP_011395034	phosphoribosyl-AMP cyclohydrolase [Hahella chejuensis].	50.88	114	55	1	18	130	10	123	4e-33	124
rs:WP_045181907	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. 5].	50.88	114	55	1	18	130	8	121	4e-33	124
rs:WP_027745722	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. CNT371].	49.12	114	55	1	2	112	1	114	4e-33	124
rs:WP_042579103	phosphoribosyl-AMP cyclohydrolase [Variovorax paradoxus].	47.86	117	57	1	18	130	7	123	4e-33	124
tr:B4XNW3_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	48.25	114	58	1	5	117	2	115	4e-33	124
tr:D4L889_9FIRM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	54.37	103	44	1	11	113	1	100	4e-33	123
rs:WP_034330783	phosphoribosyl-AMP cyclohydrolase [Herbaspirillum sp. B39].	48.70	115	55	2	16	126	9	123	4e-33	125
rs:WP_035628897	hypothetical protein, partial [Lachnospiraceae bacterium NK4A136].	54.90	102	46	0	13	114	6	107	4e-33	123
rs:WP_010073927	phosphoribosyl-AMP cyclohydrolase [Clostridium cellulovorans].	58.33	96	39	1	18	113	7	101	4e-33	123
rs:WP_008715870	phosphoribosyl-AMP cyclohydrolase [Rhodococcus sp. AW25M09].	55.10	98	44	0	15	112	8	105	4e-33	123
rs:WP_045258552	phosphoribosyl-AMP cyclohydrolase [Microbacterium hydrocarbonoxydans].	58.76	97	40	0	18	114	10	106	4e-33	123
rs:WP_018835580	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyces].	49.12	114	55	1	2	112	1	114	4e-33	124
rs:WP_003663409	phosphoribosyl-AMP cyclohydrolase [Moraxella catarrhalis].	53.45	116	52	2	17	130	10	125	4e-33	127
rs:WP_008332443	phosphoribosyl-AMP cyclohydrolase [Herbaspirillum sp. GW103].	48.70	115	55	2	16	126	9	123	4e-33	125
rs:WP_010464478	phosphoribosyl-AMP cyclohydrolase [Pseudomonas mandelii].	50.88	114	55	1	18	130	8	121	4e-33	124
rs:WP_040423611	phosphoribosyl-AMP cyclohydrolase [Corynebacterium genitalium].	58.95	95	39	0	18	112	24	118	4e-33	124
rs:WP_029521867	phosphoribosyl-ATP pyrophosphatase [Persephonella sp. KM09-Lau-8].	53.12	96	45	0	18	113	4	99	4e-33	126
rs:WP_004600102	phosphoribosyl-AMP cyclohydrolase [Turicella otitidis].	56.84	95	41	0	18	112	24	118	4e-33	124
rs:WP_028848977	phosphoribosyl-AMP cyclohydrolase [Thermocrispum municipale].	54.63	108	44	1	18	125	12	114	4e-33	123
rs:WP_027819285	phosphoribosyl-AMP cyclohydrolase [Burkholderia bannensis].	57.89	95	39	1	24	117	20	114	4e-33	124
rs:WP_028971848	phosphoribosyl-ATP pyrophosphatase [Sporomusa ovata].	56.57	99	43	0	14	112	3	101	4e-33	126
rs:WP_047015218	phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. CNQ-509].	55.79	95	42	0	18	112	20	114	4e-33	124
rs:WP_008062024	phosphoribosyl-AMP cyclohydrolase [Methyloversatilis universalis].	52.43	103	48	1	18	119	10	112	4e-33	124
sp:HIS3_CHLPB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.61	97	45	0	17	113	14	110	4e-33	124
rs:WP_027811786	phosphoribosyl-AMP cyclohydrolase [Burkholderia cenocepacia].	45.24	126	65	2	5	126	2	127	4e-33	124
rs:WP_014760265	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium bifidum].	53.10	113	44	1	9	112	6	118	4e-33	124
gpu:CP011477_2817	phosphoribosyl-AMP cyclohydrolase [Spongiibacter sp. IMCC21906]	52.63	114	53	1	18	130	9	122	4e-33	124
rs:WP_036604599	phosphoribosyl-AMP cyclohydrolase [Paenibacillus sophorae].	55.34	103	45	1	17	118	12	114	4e-33	128
rs:WP_020014736	phosphoribosyl-AMP cyclohydrolase [Promicromonospora sukumoe].	51.28	117	57	0	15	131	10	126	4e-33	124
rs:WP_037237471	phosphoribosyl-AMP cyclohydrolase [Rhodococcus wratislaviensis].	56.70	97	42	0	16	112	9	105	4e-33	123
tr:B4XNB5_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	46.03	126	64	2	5	126	2	127	4e-33	124
rs:WP_032394334	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Rhodococcus].	56.12	98	43	0	15	112	8	105	4e-33	123
rs:WP_025962279	imidazole glycerol phosphate synthase [Prochlorococcus sp. scB245a_521K15].	53.27	107	49	1	12	117	6	112	4e-33	126
rs:WP_040321425	phosphoribosyl-AMP cyclohydrolase [Austwickia chelonae].	56.70	97	42	0	18	114	22	118	4e-33	124
rs:WP_009852460	phosphoribosyl-AMP cyclohydrolase [beta proteobacterium KB13].	47.71	109	56	1	18	125	7	115	4e-33	124
rs:WP_041253910	phosphoribosyl-AMP cyclohydrolase [Frankia sp. EAN1pec].	54.72	106	45	1	10	112	5	110	4e-33	124
rs:WP_013163579	phosphoribosyl-AMP cyclohydrolase [Desulfurivibrio alkaliphilus].	56.86	102	42	2	22	121	8	109	4e-33	124
rs:WP_011936036	phosphoribosyl-ATP pyrophosphatase [Synechococcus sp. RCC307].	57.14	112	44	2	10	120	4	112	4e-33	126
rs:WP_013119730	phosphoribosyl-ATP pyrophosphatase [Thermincola potens].	53.27	107	50	0	11	117	1	107	4e-33	126
tr:T0IG59_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	56.57	99	43	0	14	112	2	100	4e-33	126
rs:WP_035035391	phosphoribosyl-AMP cyclohydrolase [Aquabacterium sp. NJ1].	50.00	106	49	1	18	119	7	112	4e-33	124
tr:K6V4Y6_9MICO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	56.70	97	42	0	18	114	19	115	4e-33	124
rs:WP_021941226	phosphoribosyl-ATP diphosphatase [Clostridium sp. CAG:632].	53.57	112	50	1	2	113	200	309	4e-33	130
rs:WP_033073209	phosphoribosyl-AMP cyclohydrolase [Sphingopyxis sp. MWB1].	54.55	99	45	0	19	117	14	112	4e-33	124
tr:A0A076F2V0_RHOOP	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	56.70	97	42	0	16	112	9	105	4e-33	123
rs:WP_018230211	phosphoribosyl-AMP cyclohydrolase [Methyloversatilis universalis].	52.43	103	48	1	18	119	10	112	5e-33	124
rs:WP_043199946	phosphoribosyl-AMP cyclohydrolase [Pseudomonas putida].	48.31	118	59	1	2	117	5	122	5e-33	124
rs:WP_019239473	phosphoribosyl-AMP cyclohydrolase [Collinsella sp. GD3].	56.44	101	44	0	17	117	5	105	5e-33	123
rs:WP_023508736	phosphoribosyl-ATP pyrophosphatase [Sporolactobacillus laevolacticus].	55.24	105	47	0	17	121	5	109	5e-33	126
tr:A0A0B6ERW8_9CORY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	62.11	95	35	1	18	112	25	118	5e-33	124
rs:WP_035654295	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. JGI 0001002-A22].	54.55	99	45	0	19	117	19	117	5e-33	124
rs:WP_046773005	phosphoribosyl-AMP cyclohydrolase [Jiangella alkaliphila].	58.95	95	39	0	18	112	12	106	5e-33	123
sp:HIS3_NITWN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	55.00	100	45	0	20	119	20	119	5e-33	124
rs:WP_029481137	imidazole glycerol phosphate synthase [Deinococcus marmoris].	58.42	101	42	0	14	114	8	108	5e-33	126
tr:D6YA21_THEBD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	57.89	95	40	0	18	112	39	133	5e-33	124
rs:WP_036500517	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Nocardia].	58.95	95	39	0	18	112	11	105	5e-33	123
rs:WP_010781497	phosphoribosyl-ATP diphosphatase [Enterococcus gilvus].	48.70	115	59	0	16	130	2	116	5e-33	126
rs:WP_015902420	phosphoribosyl-ATP pyrophosphatase [Nautilia profundicola].	58.24	91	38	0	24	114	9	99	5e-33	126
rs:WP_022500478	hypothetical protein [Firmicutes bacterium CAG:95].	59.38	96	39	0	18	113	230	325	5e-33	130
rs:WP_046551715	phosphoribosyl-ATP diphosphatase [Sulfurovum lithotrophicum].	51.82	110	51	1	17	126	7	114	5e-33	126
rs:WP_040292551	phosphoribosyl-ATP pyrophosphatase [Acetonema longum].	53.92	102	47	0	11	112	2	103	5e-33	126
gp:AB091436_10	phosphoribosyl-AMP cyclohydrolase [Burkholderia multivorans ATCC 17616]	45.24	126	65	2	5	126	2	127	5e-33	124
rs:WP_027705702	phosphoribosyl-AMP cyclohydrolase [Zymobacter palmae].	50.42	119	59	0	10	128	20	138	5e-33	124
rs:WP_011612285	phosphoribosyl-ATP pyrophosphatase [Trichodesmium erythraeum].	58.59	99	40	1	18	115	18	116	5e-33	126
rs:WP_006235892	phosphoribosyl-AMP cyclohydrolase [Collinsella aerofaciens].	58.33	96	40	0	18	113	10	105	5e-33	123
tr:F7NEP4_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	53.92	102	47	0	11	112	1	102	5e-33	126
rs:WP_035158305	imidazole glycerol phosphate synthase [Calothrix sp. 336/3].	50.00	116	57	1	1	115	1	116	5e-33	126
tr:A0A074UIU1_9MICO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	56.84	95	41	0	18	112	6	100	5e-33	123
rs:WP_013646805	phosphoribosyl-AMP cyclohydrolase [Nitrosomonas sp. AL212].	47.41	116	60	1	16	130	8	123	5e-33	124
tr:A0A076H4R2_9SYNE	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	60.82	97	37	1	18	113	4	100	5e-33	126
rs:WP_030514639	phosphoribosyl-AMP cyclohydrolase [Nocardia sp. NRRL WC-3656].	58.95	95	39	0	18	112	11	105	5e-33	123
rs:WP_013077705	phosphoribosyl-AMP cyclohydrolase [Caulobacter segnis].	54.37	103	45	1	19	119	24	126	5e-33	124
tr:A0A0D6APY4_9CHRO	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:BAQ64933.1};	56.57	99	42	1	18	115	18	116	5e-33	126
rs:WP_038591344	phosphoribosyl-AMP cyclohydrolase [Corynebacterium imitans].	57.73	97	41	0	16	112	19	115	5e-33	123
rs:WP_036737562	phosphoribosyl-ATP pyrophosphatase [Persephonella sp. IF05-L8].	53.12	96	45	0	18	113	5	100	5e-33	125
rs:WP_012335962	phosphoribosyl-AMP cyclohydrolase [Methylobacterium sp. 4-46].	59.05	105	41	1	17	119	21	125	5e-33	124
rs:WP_015121245	phosphoribosyl-AMP cyclohydrolase [Rivularia sp. PCC 7116].	56.57	99	42	1	18	115	17	115	5e-33	126
rs:WP_037150777	phosphoribosyl-AMP cyclohydrolase [Rhodococcus fascians].	53.27	107	50	0	15	121	8	114	5e-33	123
rs:WP_037192701	phosphoribosyl-AMP cyclohydrolase [Rhodococcus fascians].	56.12	98	43	0	15	112	8	105	5e-33	123
tr:U2C9T1_BIFBR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.54	118	47	1	4	112	5	122	5e-33	124
rs:WP_043620460	phosphoribosyl-AMP cyclohydrolase [Chromobacterium piscinae].	53.85	104	47	1	18	120	7	110	5e-33	123
rs:WP_045164831	imidazole glycerol phosphate synthase [Thermoanaerobacter cellulolyticus].	52.94	102	48	0	13	114	2	103	5e-33	125
rs:WP_028548974	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. UNC451MF].	54.90	102	46	0	15	116	18	119	5e-33	126
rs:WP_016459589	phosphoribosyl-ATP diphosphatase [Acidaminococcus intestini CAG:325].	54.95	111	49	1	11	120	1	111	5e-33	126
rs:WP_047215793	phosphoribosyl-AMP cyclohydrolase [Pandoraea thiooxydans].	52.88	104	48	1	18	120	9	112	5e-33	124
rs:WP_035602165	phosphoribosyl-AMP cyclohydrolase [Haloferula sp. BvORR071].	57.43	101	42	1	17	116	20	120	5e-33	124
rs:WP_026598024	phosphoribosyl-AMP cyclohydrolase [Methylocystis sp. LW5].	53.04	115	47	2	19	126	21	135	5e-33	124
rs:WP_004046840	phosphoribosyl-AMP cyclohydrolase [Halorubrum saccharovorum].	55.00	100	45	0	18	117	13	112	5e-33	123
rs:WP_009678605	phosphoribosyl-AMP cyclohydrolase [Gordonia neofelifaecis].	56.57	99	43	0	16	114	9	107	5e-33	123
rs:WP_024803856	phosphoribosyl-AMP cyclohydrolase [Nocardia sp. BMG51109].	58.95	95	39	0	18	112	11	105	5e-33	123
rs:WP_015485425	phosphoribosyl-AMP cyclohydrolase [Thalassolituus oleivorans].	54.05	111	49	2	17	126	6	115	5e-33	123
rs:WP_007868115	phosphoribosyl-AMP cyclohydrolase [Polaromonas sp. CF318].	47.86	117	57	1	18	130	7	123	5e-33	124
rs:WP_013009628	phosphoribosyl-AMP cyclohydrolase [Denitrovibrio acetiphilus].	53.85	104	48	0	21	124	8	111	5e-33	123
rs:WP_012674844	phosphoribosyl-ATP pyrophosphatase [Sulfurihydrogenibium azorense].	42.61	115	64	1	17	129	7	121	5e-33	125
rs:WP_028603245	phosphoribosyl-AMP cyclohydrolase [Ottowia thiooxydans].	48.72	117	56	1	18	130	7	123	5e-33	123
rs:WP_036188725	phosphoribosyl-AMP cyclohydrolase [Marinimicrobium agarilyticum].	53.70	108	49	1	24	130	23	130	5e-33	124
rs:WP_034417643	imidazole glycerol phosphate synthase [Candidatus Synechococcus spongiarum].	61.22	98	37	1	17	113	8	105	5e-33	126
rs:WP_007117212	phosphoribosyl-AMP cyclohydrolase [Enhydrobacter aerosaccus].	52.21	113	52	2	7	118	3	114	5e-33	128
rs:WP_038545463	imidazole glycerol phosphate synthase [Synechococcus sp. KORDI-100].	60.82	97	37	1	18	113	12	108	5e-33	126
rs:WP_013389119	phosphoribosyl-ATP pyrophosphatase [Ilyobacter polytropus].	54.00	100	46	0	17	116	3	102	5e-33	125
rs:WP_032522553	imidazole glycerol phosphate synthase [Prochlorococcus marinus].	51.38	109	52	1	10	117	4	112	5e-33	126
rs:WP_035531636	phosphoribosyl-AMP cyclohydrolase [Burkholderia sacchari].	54.46	101	45	1	18	117	23	123	5e-33	124
rs:WP_019654397	phosphoribosyl-AMP cyclohydrolase [Variovorax paradoxus].	47.01	117	58	1	18	130	7	123	5e-33	123
rs:WP_015401252	phosphoribosyl-AMP cyclohydrolase [Corynebacterium halotolerans].	60.00	95	38	0	18	112	24	118	5e-33	123
rs:WP_018263472	phosphoribosyl-AMP cyclohydrolase [Methylobacterium sp. WSM2598].	59.05	105	41	1	17	119	21	125	6e-33	124
rs:WP_038773048	phosphoribosyl-AMP cyclohydrolase [Burkholderia pseudomallei].	51.33	113	51	2	18	126	14	126	6e-33	124
rs:WP_022387589	phosphoribosyl-AMP cyclohydrolase [Collinsella sp. CAG:289].	58.00	100	42	0	18	117	10	109	6e-33	123
rs:WP_044911652	MULTISPECIES: hypothetical protein [Dorea].	55.36	112	48	1	2	113	204	313	6e-33	130
rs:WP_028575628	phosphoribosyl-AMP cyclohydrolase [Desulfonatronovibrio hydrogenovorans].	54.63	108	44	2	24	126	10	117	6e-33	123
rs:WP_029069621	phosphoribosyl-AMP cyclohydrolase [Jonesia quinghaiensis].	53.51	114	52	1	9	121	5	118	6e-33	123
rs:WP_011955002	phosphoribosyl-ATP pyrophosphatase [Roseiflexus sp. RS-1].	58.33	96	40	0	18	113	6	101	6e-33	125
rs:WP_045085476	phosphoribosyl-AMP cyclohydrolase [[Clostridium] cellulosi].	56.38	94	41	0	20	113	5	98	6e-33	122
rs:WP_015438852	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium breve].	60.00	95	38	0	18	112	20	114	6e-33	123
rs:WP_046406151	phosphoribosyl-AMP cyclohydrolase [Clostridium sp. A254.MGS-251].	57.14	98	42	0	20	117	7	104	6e-33	123
rs:WP_019480233	phosphoribosyl-ATP pyrophosphatase [Prochlorococcus sp. W11].	51.35	111	53	1	12	121	6	116	6e-33	126
rs:WP_027525634	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. Ec3.3].	56.57	99	43	0	19	117	17	115	6e-33	124
rs:WP_006853300	phosphoribosyl-ATP pyrophosphatase [Synechococcus sp. WH 8016].	61.86	97	36	1	18	113	12	108	6e-33	126
sp:HIS3_VESOH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	45.61	114	61	1	18	130	7	120	6e-33	123
rs:WP_046156242	phosphoribosyl-AMP cyclohydrolase [Chromobacterium vaccinii].	52.88	104	48	1	18	120	7	110	6e-33	123
rs:WP_033125247	hypothetical protein [Eubacterium sp. ER2].	55.36	112	48	1	2	113	215	324	6e-33	130
rs:WP_022260068	phosphoribosyl-AMP cyclohydrolase [Eubacterium sp. CAG:251].	57.14	98	42	0	20	117	8	105	6e-33	123
rs:WP_013117222	phosphoribosyl-AMP cyclohydrolase [Cellulomonas flavigena].	60.00	95	38	0	18	112	55	149	6e-33	125
rs:WP_003935801	phosphoribosyl-AMP cyclohydrolase [Rhodococcus ruber].	58.95	95	39	0	18	112	12	106	6e-33	123
rs:WP_042533321	phosphoribosyl-AMP cyclohydrolase, partial [Corynebacterium singulare].	62.11	95	35	1	18	112	25	118	6e-33	123
rs:WP_039728075	MULTISPECIES: imidazole glycerol phosphate synthase [Oscillatoriophycideae].	53.70	108	49	1	9	115	4	111	6e-33	125
sp:HIS3_NITEC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	49.57	115	57	1	17	130	8	122	6e-33	123
sp:HIS3_BIFAA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	57.89	95	40	0	18	112	20	114	6e-33	124
rs:WP_007982211	phosphoribosyl-AMP cyclohydrolase [Haladaptatus paucihalophilus].	55.21	96	43	0	18	113	9	104	6e-33	124
rs:WP_025938085	imidazole glycerol phosphate synthase [Prochlorococcus sp. scB245a_519A13].	51.38	109	52	1	10	117	4	112	6e-33	126
sp:HIS3_METTP	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	57.14	98	42	0	16	113	3	100	6e-33	123
rs:WP_046432103	phosphoribosyl-AMP cyclohydrolase [Ruminococcus sp. A254.MGS-108].	54.37	103	44	1	11	113	1	100	6e-33	122
rs:WP_035768342	phosphoribosyl-AMP cyclohydrolase, partial [Arthrobacter castelli].	62.11	95	36	0	18	112	34	128	6e-33	124
rs:WP_008287123	phosphoribosyl-ATP pyrophosphatase [Hydrogenivirga sp. 128-5-R1-1].	54.46	101	45	1	18	117	4	104	6e-33	125
rs:WP_009014773	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Acidaminococcus].	54.95	111	49	1	11	120	4	114	6e-33	126
tr:A0A087DPF0_9BIFI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	60.00	95	38	0	18	112	20	114	6e-33	124
rs:WP_040718465	phosphoribosyl-AMP cyclohydrolase [Nocardia veterana].	55.24	105	44	1	11	112	1	105	6e-33	123
rs:WP_012595968	phosphoribosyl-ATP pyrophosphatase [Cyanothece sp. PCC 8801].	57.00	100	42	1	17	115	11	110	6e-33	125
rs:WP_011979930	phosphoribosyl-ATP pyrophosphatase [Sulfurovum sp. NBC37-1].	51.82	110	51	1	17	126	2	109	6e-33	126
rs:WP_025885630	phosphoribosyl-AMP cyclohydrolase [Asaia prunellae].	54.81	104	46	1	11	113	11	114	6e-33	124
rs:WP_011619816	phosphoribosyl-ATP pyrophosphatase [Synechococcus sp. CC9311].	61.86	97	36	1	18	113	12	108	6e-33	126
rs:WP_032513840	imidazole glycerol phosphate synthase [Prochlorococcus marinus].	54.37	103	46	1	12	113	6	108	6e-33	126
rs:WP_015784676	phosphoribosyl-ATP pyrophosphatase [Cyanothece sp. PCC 8802].	57.00	100	42	1	17	115	11	110	6e-33	125
rs:WP_034528445	phosphoribosyl-AMP cyclohydrolase, partial [Bifidobacterium stellenboschense].	60.00	95	38	0	18	112	20	114	6e-33	123
rs:WP_017291358	phosphoribosyl-ATP pyrophosphatase [Leptolyngbya boryana].	53.70	108	49	1	9	115	8	115	6e-33	125
rs:WP_007072124	phosphoribosyl-AMP cyclohydrolase [Micromonospora sp. ATCC 39149].	56.70	97	42	0	18	114	37	133	6e-33	124
rs:WP_039916965	phosphoribosyl-AMP cyclohydrolase [Amycolatopsis azurea].	54.63	108	44	1	18	125	11	113	6e-33	123
rs:WP_027874097	phosphoribosyl-AMP cyclohydrolase [Spongiibacter marinus].	52.21	113	49	2	2	113	1	109	6e-33	123
rs:WP_046528506	phosphoribosyl-AMP cyclohydrolase [Cellulomonas sp. FA1].	57.14	105	44	1	9	112	18	122	6e-33	124
rs:WP_007197486	phosphoribosyl-AMP cyclohydrolase [Hoeflea phototrophica].	55.45	101	43	1	19	117	24	124	6e-33	124
tr:E7S0Y3_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	55.34	103	45	1	18	119	25	127	7e-33	125
gpu:CP009503_2516	Phosphoribosyl-AMP cyclohydrolase [Methanosarcina sp. WWM596]	57.28	103	41	2	11	113	2	101	7e-33	123
rs:WP_020144027	phosphoribosyl-AMP cyclohydrolase [Terracoccus sp. 273MFTsu3.1].	60.00	95	38	0	18	112	22	116	7e-33	123
rs:WP_007061405	phosphoribosyl-AMP cyclohydrolase [Clostridium carboxidivorans].	52.68	112	50	2	2	113	1	109	7e-33	123
rs:WP_028560925	phosphoribosyl-ATP pyrophosphatase [Paenibacillus pinihumi].	51.96	102	49	0	13	114	6	107	7e-33	126
rs:WP_014376063	phosphoribosyl-AMP cyclohydrolase [Blastococcus saxobsidens].	58.33	96	40	0	18	113	19	114	7e-33	123
rs:WP_028599286	phosphoribosyl-ATP pyrophosphatase [Paenibacillus pasadenensis].	50.00	114	56	1	2	114	1	114	7e-33	126
rs:WP_042269652	phosphoribosyl-AMP cyclohydrolase [Burkholderia heleia].	54.46	101	45	1	18	117	22	122	7e-33	124
rs:WP_015200388	phosphoribosyl-AMP cyclohydrolase [Calothrix parietina].	54.00	100	45	1	17	115	17	116	7e-33	125
tr:U2PIX7_EUBRA	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	52.54	118	54	1	16	131	226	343	7e-33	129
tr:A0A0B6WT40_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	57.14	98	42	0	15	112	4	101	7e-33	126
rs:WP_029269641	phosphoribosyl-ATP pyrophosphatase [Virgibacillus alimentarius].	54.37	103	47	0	11	113	2	104	7e-33	125
rs:WP_016186448	hypothetical protein [Enterococcus sulfureus].	55.91	93	41	0	24	116	10	102	7e-33	122
sp:HIS3_CAUSK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	56.73	104	43	1	19	120	25	128	7e-33	123
rs:WP_029089117	phosphoribosyl-AMP cyclohydrolase [Brevibacterium album].	56.84	95	41	0	18	112	9	103	7e-33	123
rs:WP_022789233	phosphoribosyl-AMP cyclohydrolase [[Streptococcus] pleomorphus].	53.61	97	45	0	21	117	8	104	7e-33	122
rs:WP_026891369	phosphoribosyl-ATP diphosphatase [[Clostridium] aerotolerans].	57.14	105	43	1	9	113	222	324	7e-33	129
rs:WP_041974359	phosphoribosyl-ATP pyrophosphatase [Pyrinomonas methylaliphatogenes].	57.14	98	42	0	15	112	7	104	7e-33	126
tr:A0A0D6AFJ4_9CHRO	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:BAQ61563.1};	55.56	99	43	1	18	115	18	116	7e-33	125
rs:WP_014192413	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. YI23].	53.33	105	48	1	18	121	11	115	7e-33	123
rs:WP_013410826	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium longum].	60.00	95	38	0	18	112	20	114	7e-33	123
rs:WP_043164074	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium callitrichos].	60.00	95	38	0	18	112	20	114	7e-33	123
rs:WP_046167678	phosphoribosyl-AMP cyclohydrolase [Chromobacterium vaccinii].	52.88	104	48	1	18	120	7	110	7e-33	123
tr:A8LGR4_FRASN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.72	106	45	1	10	112	20	125	7e-33	124
rs:WP_008935825	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Brucella].	52.63	114	52	1	19	130	23	136	7e-33	123
rs:WP_041780184	imidazole glycerol phosphate synthase [Microcoleus sp. PCC 7113].	56.57	99	42	1	18	115	19	117	7e-33	125
rs:WP_024734746	phosphoribosyl-ATP diphosphatase, partial [Clostridiales bacterium VE202-15].	49.19	124	55	2	2	117	206	329	7e-33	129
rs:WP_004653485	hypothetical protein [Acinetobacter sp. NIPH 809].	52.63	114	52	1	2	113	10	123	7e-33	123
rs:WP_015061089	phosphoribosyl-AMP cyclohydrolase [Pseudomonas sp. K-62].	54.13	109	48	1	19	125	19	127	7e-33	123
sp:HIS3_NOCFA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	57.89	95	40	0	18	112	11	105	7e-33	122
rs:WP_026645931	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium ruminantium].	57.89	95	40	0	18	112	21	115	7e-33	123
rs:WP_013907612	phosphoribosyl-AMP cyclohydrolase [Thermodesulfatator indicus].	52.29	109	51	1	23	130	10	118	7e-33	123
rs:WP_019403249	hypothetical protein [Chelatococcus sp. GW1].	54.46	112	46	2	20	126	27	138	7e-33	123
rs:WP_028206577	phosphoribosyl-AMP cyclohydrolase [Burkholderia nodosa].	53.47	101	46	1	18	117	22	122	7e-33	124
tr:A0A069NSC2_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.38	105	49	1	18	121	13	117	7e-33	123
rs:WP_032517730	imidazole glycerol phosphate synthase [Prochlorococcus marinus].	51.38	109	52	1	10	117	4	112	7e-33	125
rs:WP_008505223	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Brucella].	52.63	114	52	1	19	130	23	136	7e-33	123
rs:WP_035967690	phosphoribosyl-AMP cyclohydrolase [Burkholderia grimmiae].	52.38	105	49	1	18	121	11	115	8e-33	123
rs:WP_012746325	phosphoribosyl-AMP cyclohydrolase [Variovorax paradoxus].	47.86	117	57	1	18	130	7	123	8e-33	123
rs:WP_032682366	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium longum].	60.00	95	38	0	18	112	20	114	8e-33	123
rs:WP_003834725	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bifidobacterium].	57.89	95	40	0	18	112	20	114	8e-33	123
rs:WP_012878267	phosphoribosyl-AMP cyclohydrolase [Xylanimonas cellulosilytica].	59.79	97	39	0	16	112	11	107	8e-33	123
rs:WP_032403992	phosphoribosyl-AMP cyclohydrolase [Rhodococcus fascians].	55.10	98	44	0	15	112	8	105	8e-33	123
rs:WP_010621299	phosphoribosyl-AMP cyclohydrolase [Lactobacillus suebicus].	51.89	106	50	1	19	123	5	110	8e-33	122
rs:WP_032744158	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium longum].	60.00	95	38	0	18	112	20	114	8e-33	123
rs:WP_012007396	phosphoribosyl-ATP pyrophosphatase [Prochlorococcus marinus].	51.38	109	52	1	10	117	4	112	8e-33	125
tr:X1S1P4_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_L04073 {ECO:0000313|EMBL:GAI86803.1};	50.00	108	53	1	19	125	16	123	8e-33	123
rs:WP_041115607	phosphoribosyl-ATP pyrophosphatase [Bacillus pumilus].	54.21	107	46	1	16	122	5	108	8e-33	125
rs:WP_009060453	phosphoribosyl-AMP cyclohydrolase [Clostridium sp. MSTE9].	54.90	102	46	0	20	121	17	118	8e-33	122
rs:WP_022036100	imidazole glycerol phosphate synthase subunit HisF [Roseburia sp. CAG:50].	52.54	118	54	1	16	131	226	343	8e-33	129
rs:WP_013140808	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium longum].	60.00	95	38	0	18	112	20	114	8e-33	123
rs:WP_038294880	phosphoribosyl-AMP cyclohydrolase [actinobacterium acMicro-1].	60.22	93	37	0	20	112	9	101	8e-33	123
rs:WP_013501746	phosphoribosyl-AMP cyclohydrolase [Rhodopseudomonas palustris].	52.88	104	48	1	19	121	26	129	8e-33	124
rs:WP_007240043	phosphoribosyl-AMP cyclohydrolase [Gordonia otitidis].	57.00	100	43	0	15	114	8	107	8e-33	123
rs:WP_013704259	phosphoribosyl-ATP pyrophosphatase [Marinithermus hydrothermalis].	47.79	113	59	0	13	125	1	113	8e-33	125
sp:HIS3_BIFLD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	60.00	95	38	0	18	112	20	114	8e-33	123
rs:WP_011862594	phosphoribosyl-ATP pyrophosphatase [Prochlorococcus marinus].	51.38	109	52	1	10	117	4	112	8e-33	125
rs:WP_033059259	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Clostridium].	59.14	93	38	0	22	114	15	107	8e-33	122
rs:WP_041422772	phosphoribosyl-AMP cyclohydrolase [Slackia heliotrinireducens].	53.85	104	45	1	11	114	1	101	8e-33	122
gpu:CP009524_1779	Phosphoribosyl-AMP cyclohydrolase [Methanosarcina sp. Kolksee]	56.07	107	44	2	11	117	2	105	8e-33	123
rs:WP_032519331	imidazole glycerol phosphate synthase [Prochlorococcus marinus].	51.38	109	52	1	10	117	4	112	8e-33	125
sp:HIS2_PROMP	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	50.46	109	53	1	10	117	4	112	8e-33	125
tr:C9X0T9_NEIM8	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	51.72	116	55	1	17	131	8	123	8e-33	123
rs:WP_003840060	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bifidobacterium].	57.73	97	41	0	16	112	18	114	8e-33	123
rs:WP_016390840	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Cycloclasticus].	50.88	114	55	1	18	130	8	121	8e-33	123
rs:WP_043723245	phosphoribosyl-AMP cyclohydrolase [Nocardia asiatica].	56.84	95	41	0	18	112	11	105	8e-33	122
rs:WP_022721336	phosphoribosyl-AMP cyclohydrolase [Rhodopseudomonas sp. B29].	52.88	104	48	1	19	121	24	127	8e-33	124
rs:WP_046010186	phosphoribosyl-AMP cyclohydrolase [Oleispira antarctica].	55.56	99	43	1	18	115	8	106	8e-33	123
rs:WP_015006924	phosphoribosyl-AMP cyclohydrolase [Cycloclasticus sp. P1].	50.88	114	55	1	18	130	8	121	8e-33	123
rs:WP_013806248	phosphoribosyl-AMP cyclohydrolase [Amycolicicoccus subflavus].	53.15	111	47	1	15	125	11	116	8e-33	122
rs:WP_043714217	phosphoribosyl-ATP pyrophosphatase [Symbiobacterium thermophilum].	55.75	113	49	1	14	126	3	114	8e-33	126
rs:WP_045845765	phosphoribosyl-AMP cyclohydrolase [Aquitalea magnusonii].	50.88	114	55	1	18	130	8	121	8e-33	123
rs:WP_012962828	phosphoribosyl-ATP pyrophosphatase [Hydrogenobacter thermophilus].	58.16	98	40	1	17	113	3	100	8e-33	125
rs:WP_013841341	phosphoribosyl-ATP pyrophosphatase [Desulfotomaculum ruminis].	57.94	107	44	1	11	116	1	107	8e-33	126
rs:WP_040891711	phosphoribosyl-ATP diphosphatase, partial [Verminephrobacter aporrectodeae].	49.57	115	54	1	18	128	7	121	8e-33	126
rs:WP_022225411	phosphoribosyl-ATP diphosphatase [Clostridium sp. CAG:253].	56.00	100	44	0	14	113	220	319	8e-33	129
rs:WP_003845299	phosphoribosyl-AMP cyclohydrolase [Corynebacterium ammoniagenes].	58.95	95	38	1	18	112	32	125	8e-33	123
gpu:CP011311_1471	phosphoribosyl-AMP cyclohydrolase [Corynebacterium camporealensis]	52.17	115	51	2	1	112	1	114	8e-33	123
rs:WP_007779356	phosphoribosyl-ATP pyrophosphatase [Desulfosporosinus youngiae].	51.79	112	53	1	13	123	9	120	8e-33	125
sp:HIS2_THET2	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	50.47	107	53	0	13	119	1	107	8e-33	125
rs:WP_011818082	phosphoribosyl-ATP pyrophosphatase [Prochlorococcus marinus].	51.38	109	52	1	10	117	4	112	9e-33	125
rs:WP_043535042	phosphoribosyl-AMP cyclohydrolase [Actinomyces sp. MS2].	56.60	106	45	1	8	112	3	108	9e-33	122
rs:WP_032514937	imidazole glycerol phosphate synthase [Prochlorococcus marinus].	51.38	109	52	1	10	117	4	112	9e-33	125
sp:HIS3_BRUC2	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.63	114	52	1	19	130	23	136	9e-33	123
rs:WP_020931925	phosphoribosyl-AMP cyclohydrolase [Cycloclasticus zancles].	50.88	114	55	1	18	130	8	121	9e-33	123
rs:WP_025924309	MULTISPECIES: imidazole glycerol phosphate synthase [Prochlorococcus].	51.38	109	52	1	10	117	4	112	9e-33	125
rs:WP_035035917	phosphoribosyl-AMP cyclohydrolase [Caulobacter sp. AP07].	56.73	104	43	1	19	120	24	127	9e-33	123
tr:J2GR27_9CAUL	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	56.73	104	43	1	19	120	27	130	9e-33	123
rs:WP_035254589	phosphoribosyl-AMP cyclohydrolase [Agrococcus lahaulensis].	53.70	108	45	1	18	120	7	114	9e-33	122
rs:WP_025894218	MULTISPECIES: imidazole glycerol phosphate synthase [Prochlorococcus].	51.38	109	52	1	10	117	4	112	9e-33	125
rs:WP_041337174	phosphoribosyl-AMP cyclohydrolase [Ruminococcus bicirculans].	53.40	103	48	0	20	122	15	117	9e-33	122
gp:CP002221_179	phosphoribosyl-ATP diphosphatase [Hydrogenobacter thermophilus TK-6]	58.16	98	40	1	17	113	2	99	9e-33	125
gp:HG803175_1045	hisI gene product [Brucella canis str. Oliveri]	52.63	114	52	1	19	130	3	116	9e-33	122
rs:XP_005708249	bifunctional phosphoribosyl-ATP diphosphatase / phosphoribosyl-AMPcyclohydrolase isoform 1 [Galdieria sulphuraria].	58.33	96	40	0	18	113	68	163	9e-33	124
rs:WP_046844338	imidazole glycerol phosphate synthase ['Deinococcus soli' Cha et al. 2014].	50.83	120	57	2	9	126	3	122	9e-33	125
rs:WP_038552370	phosphoribosyl-AMP cyclohydrolase [Corynebacterium glyciniphilum].	52.83	106	49	1	8	112	3	108	9e-33	122
rs:WP_039812648	phosphoribosyl-AMP cyclohydrolase [Nocardia otitidiscaviarum].	57.89	95	40	0	18	112	11	105	9e-33	122
rs:WP_022205374	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [Eubacterium sp. CAG:248].	58.33	96	40	0	18	113	259	354	9e-33	129
rs:WP_011228687	phosphoribosyl-ATP pyrophosphatase [Thermus thermophilus].	50.47	107	53	0	13	119	1	107	9e-33	125
rs:WP_044982042	hypothetical protein [Lachnospiraceae bacterium NK4A144].	57.14	98	42	0	16	113	241	338	9e-33	129
gpu:CP011452_485	phosphoribosyl-AMP cyclohydrolase [Altererythrobacter atlanticus]	46.34	123	63	2	3	124	9	129	9e-33	123
rs:WP_028163263	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium elkanii].	52.53	99	47	0	19	117	17	115	9e-33	123
rs:WP_015910881	phosphoribosyl-AMP cyclohydrolase [Halorubrum lacusprofundi].	54.00	100	46	0	18	117	13	112	9e-33	123
rs:WP_020071638	phosphoribosyl-AMP cyclohydrolase [[Clostridium] sporosphaeroides].	54.90	102	46	0	20	121	17	118	9e-33	122
rs:WP_008632956	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Thermus].	50.47	107	53	0	13	119	1	107	9e-33	125
rs:WP_017713455	phosphoribosyl-ATP pyrophosphatase [Prochlorothrix hollandica].	56.73	104	43	2	17	119	15	117	9e-33	125
rs:WP_045363389	phosphoribosyl-AMP cyclohydrolase [bacterium endosymbiont of Mortierella elongata FMR23-6].	53.92	102	46	1	17	117	8	109	9e-33	123
rs:WP_017622164	phosphoribosyl-AMP cyclohydrolase [Nocardiopsis chromatogenes].	55.56	108	43	1	18	120	26	133	9e-33	123
rs:WP_033523907	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium merycicum].	53.15	111	43	1	11	112	1	111	9e-33	123
rs:WP_026922012	phosphoribosyl-AMP cyclohydrolase [Glomeribacter sp. 1016415].	54.46	101	45	1	18	117	9	109	9e-33	123
rs:WP_008370557	imidazole glycerol phosphate synthase [Coprococcus comes].	55.17	116	49	2	9	123	222	335	9e-33	129
rs:WP_017579832	phosphoribosyl-AMP cyclohydrolase [Nocardiopsis valliformis].	58.95	95	39	0	18	112	14	108	9e-33	122
rs:WP_024340716	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium japonicum].	55.56	99	44	0	19	117	17	115	9e-33	123
rs:WP_044090261	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium reuteri].	58.76	97	40	0	16	112	18	114	9e-33	123
rs:WP_025967952	imidazole glycerol phosphate synthase [Prochlorococcus sp. scB245a_518I6].	51.38	109	52	1	10	117	4	112	9e-33	125
tr:K9WKY0_9CYAN	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	57.73	97	40	1	18	113	34	130	9e-33	125
rs:WP_008819242	phosphoribosyl-AMP cyclohydrolase [Clostridium sp. HGF2].	56.38	94	41	0	24	117	11	104	9e-33	122
rs:WP_017918337	phosphoribosyl-AMP cyclohydrolase [Burkholderia gladioli].	45.08	122	66	1	1	121	1	122	1e-32	123
rs:WP_003349404	phosphoribosyl-ATP pyrophosphatase [Bacillus methanolicus].	53.54	99	46	0	14	112	2	100	1e-32	125
rs:WP_024835847	phosphoribosyl-ATP diphosphatase [Clostridium sp. 12(A)].	57.14	105	43	1	9	113	222	324	1e-32	129
rs:WP_027979838	phosphoribosyl-AMP cyclohydrolase [gamma proteobacterium L18].	51.75	114	54	1	18	130	8	121	1e-32	123
rs:WP_026639243	phosphoribosyl-AMP cyclohydrolase [Bordetella petrii].	57.66	111	43	2	20	126	13	123	1e-32	123
rs:WP_023273042	phosphoribosyl-ATP diphosphatase [Acinetobacter nectaris].	56.60	106	44	2	18	121	10	115	1e-32	126
rs:WP_043906050	phosphoribosyl-ATP pyrophosphatase [Geobacillus stearothermophilus].	48.21	112	58	0	13	124	1	112	1e-32	125
rs:WP_025955405	imidazole glycerol phosphate synthase [Prochlorococcus sp. scB243_498I20].	51.38	109	52	1	10	117	4	112	1e-32	125
rs:WP_012867070	phosphoribosyl-AMP cyclohydrolase [Sanguibacter keddieii].	53.98	113	51	1	9	120	12	124	1e-32	123
rs:WP_043584012	phosphoribosyl-AMP cyclohydrolase [Diplosphaera colitermitum].	54.21	107	46	1	15	118	16	122	1e-32	123
rs:WP_030014074	phosphoribosyl-AMP cyclohydrolase [Curtobacterium sp. S6].	58.95	95	39	0	18	112	20	114	1e-32	123
tr:X5DST3_9CORY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.83	106	49	1	8	112	12	117	1e-32	123
tr:Q2J8L4_FRASC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.89	95	40	0	18	112	100	194	1e-32	126
rs:WP_020183625	phosphoribosyl-AMP cyclohydrolase [Methylotenera sp. 1P/1].	50.98	102	49	1	18	118	7	108	1e-32	122
rs:WP_038305734	phosphoribosyl-AMP cyclohydrolase [bacterium YEK0313].	49.59	121	56	2	5	120	10	130	1e-32	123
rs:WP_020644759	phosphoribosyl-AMP cyclohydrolase [Amycolatopsis balhimycina].	54.05	111	46	1	15	125	8	113	1e-32	122
rs:WP_040336659	phosphoribosyl-AMP cyclohydrolase [Candidatus Blastococcus massiliensis].	53.21	109	50	1	9	116	8	116	1e-32	123
rs:WP_009269556	phosphoribosyl-AMP cyclohydrolase [Peptoclostridium difficile].	56.38	94	41	0	24	117	11	104	1e-32	122
gpu:CP009507_775	Phosphoribosyl-AMP cyclohydrolase [Methanosarcina siciliae HI350]	55.14	107	45	2	11	117	2	105	1e-32	122
rs:WP_041724607	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio desulfuricans].	59.38	96	38	1	26	120	1	96	1e-32	122
rs:WP_022220611	phosphoribosyl-ATP diphosphatase [Coprococcus comes CAG:19].	55.17	116	49	2	9	123	222	335	1e-32	129
rs:WP_027183593	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio inopinatus].	55.05	109	48	1	23	130	10	118	1e-32	122
gpu:CP009526_1056	Phosphoribosyl-AMP cyclohydrolase [Methanosarcina barkeri str. Wiesmoor]	56.07	107	44	2	11	117	2	105	1e-32	122
tr:A0A016XK15_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	48.72	117	56	1	18	130	11	127	1e-32	123
rs:WP_025971902	imidazole glycerol phosphate synthase [Prochlorococcus sp. scB241_527L22].	51.38	109	52	1	10	117	4	112	1e-32	125
rs:WP_005328810	phosphoribosyl-AMP cyclohydrolase [Corynebacterium tuberculostearicum].	58.95	95	38	1	18	112	17	110	1e-32	122
rs:WP_019919454	phosphoribosyl-AMP cyclohydrolase [Methyloversatilis sp. FAM1].	52.43	103	48	1	18	119	10	112	1e-32	122
tr:A0A010NG85_9MICC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.89	95	40	0	18	112	20	114	1e-32	122
rs:WP_033496453	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium psychraerophilum].	57.89	95	40	0	18	112	22	116	1e-32	123
rs:WP_025101326	phosphoribosyl-AMP cyclohydrolase [Burkholderia sp. A1].	45.08	122	66	1	1	121	1	122	1e-32	123
rs:WP_011819957	phosphoribosyl-ATP pyrophosphatase [Prochlorococcus marinus].	49.55	111	55	1	10	119	4	114	1e-32	125
rs:WP_045707971	phosphoribosyl-AMP cyclohydrolase [Desulfobulbaceae bacterium BRH_c16a].	51.24	121	50	3	18	129	4	124	1e-32	122
rs:WP_034926776	phosphoribosyl-AMP cyclohydrolase [Candidatus Accumulibacter sp. SK-01].	57.73	97	40	1	18	113	7	103	1e-32	122
rs:WP_037122026	phosphoribosyl-AMP cyclohydrolase [Rhizobium sp. OV201].	53.78	119	49	3	17	131	23	139	1e-32	123
rs:WP_045919772	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium angulatum].	53.15	111	43	1	11	112	1	111	1e-32	122
rs:WP_019195323	hypothetical protein [Afipia birgiae].	52.29	109	50	1	19	125	19	127	1e-32	123
tr:A0A084XZT2_9PROT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.73	97	40	1	18	113	14	110	1e-32	123
gpu:CP009520_1801	Phosphoribosyl-AMP cyclohydrolase [Methanosarcina vacuolata Z-761]	56.07	107	44	2	11	117	38	141	1e-32	124
tr:D1KB98_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	46.49	114	60	1	18	130	25	138	1e-32	123
rs:WP_020163579	phosphoribosyl-AMP cyclohydrolase [Methyloversatilis universalis].	52.43	103	48	1	18	119	10	112	1e-32	122
rs:WP_009119672	phosphoribosyl-AMP cyclohydrolase [Neisseria shayeganii].	49.14	116	58	1	17	131	9	124	1e-32	123
rs:WP_028082176	imidazole glycerol phosphate synthase [Dolichospermum circinale].	56.57	99	42	1	18	115	18	116	1e-32	125
rs:WP_017320212	phosphoribosyl-ATP pyrophosphatase [cyanobacterium PCC 7702].	50.86	116	56	1	1	115	1	116	1e-32	125
rs:WP_038001922	imidazole glycerol phosphate synthase, partial [Synechococcus sp. RS9917].	61.86	97	36	1	18	113	12	108	1e-32	125
rs:WP_020022052	hypothetical protein [alpha proteobacterium SCGC AAA536-G10].	49.57	117	58	1	3	118	4	120	1e-32	122
rs:WP_021860454	hypothetical protein [Dorea sp. CAG:105].	54.46	112	49	1	2	113	215	324	1e-32	129
rs:WP_004222236	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bifidobacterium].	57.89	95	40	0	18	112	20	114	1e-32	123
rs:WP_040821516	phosphoribosyl-AMP cyclohydrolase [Nocardia jiangxiensis].	57.89	95	40	0	18	112	11	105	1e-32	122
rs:WP_028317990	phosphoribosyl-AMP cyclohydrolase [Desulfobulbus elongatus].	58.25	103	40	2	18	117	4	106	1e-32	122
rs:WP_043605692	phosphoribosyl-AMP cyclohydrolase [Cellulomonas carbonis].	57.89	95	40	0	18	112	17	111	1e-32	122
rs:WP_024314804	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Rhizobium].	53.78	119	49	3	17	131	23	139	1e-32	123
rs:WP_035611864	phosphoribosyl-AMP cyclohydrolase [Hylemonella gracilis].	48.72	117	56	1	18	130	14	130	1e-32	123
rs:WP_047308598	phosphoribosyl-AMP cyclohydrolase [Rhodopseudomonas palustris].	52.88	104	48	1	19	121	26	129	1e-32	123
rs:WP_028587735	phosphoribosyl-AMP cyclohydrolase [Desulfocurvus vexinensis].	55.96	109	45	2	12	119	5	111	1e-32	122
rs:WP_026487183	hypothetical protein [Caldanaerobius polysaccharolyticus].	54.17	96	44	0	18	113	6	101	1e-32	125
rs:WP_005179193	phosphoribosyl-AMP cyclohydrolase [Gordonia aichiensis].	52.21	113	49	1	15	122	8	120	1e-32	123
rs:WP_040619869	phosphoribosyl-AMP cyclohydrolase, partial [Rhodovulum sp. PH10].	53.92	102	46	1	19	119	23	124	1e-32	123
rs:WP_023163077	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Clostridium].	57.78	90	38	0	24	113	22	111	1e-32	122
rs:WP_038258666	phosphoribosyl-ATP diphosphatase [[Clostridium] hathewayi].	55.37	121	48	3	3	117	211	331	1e-32	129
rs:WP_014183254	phosphoribosyl-ATP pyrophosphatase [Desulfosporosinus orientis].	50.89	112	54	1	13	123	9	120	1e-32	125
rs:WP_014825991	phosphoribosyl-ATP pyrophosphatase [Desulfosporosinus acidiphilus].	48.21	112	57	1	13	123	9	120	1e-32	125
tr:A3Z575_9SYNE	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	61.86	97	36	1	18	113	12	108	1e-32	125
rs:WP_026645267	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium sp. AGR2158].	56.70	97	42	0	16	112	21	117	1e-32	123
rs:WP_022670942	phosphoribosyl-ATP pyrophosphatase [Hippea alviniae].	50.44	113	56	0	18	130	7	119	1e-32	125
rs:WP_012749649	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio magneticus].	57.43	101	42	1	23	122	10	110	1e-32	122
gpu:CP009506_804	Phosphoribosyl-AMP cyclohydrolase [Methanosarcina siciliae T4/M]	55.14	107	45	2	11	117	2	105	1e-32	122
rs:WP_028091597	imidazole glycerol phosphate synthase [Dolichospermum circinale].	56.57	99	42	1	18	115	18	116	1e-32	125
rs:WP_015053772	phosphoribosyl-AMP cyclohydrolase [Methanolobus psychrophilus].	59.00	100	40	1	18	117	7	105	1e-32	122
rs:WP_014099513	phosphoribosyl-ATP pyrophosphatase [Chloracidobacterium thermophilum].	52.83	106	50	0	15	120	2	107	1e-32	126
tr:A0A0B5ATM7_9BACL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	50.98	102	50	0	11	112	1	102	1e-32	125
rs:WP_029466294	phosphoribosyl-ATP diphosphatase [[Clostridium] hathewayi].	55.37	121	48	3	3	117	211	331	1e-32	129
rs:WP_014768406	phosphoribosyl-ATP pyrophosphatase [Sulfurospirillum barnesii].	52.94	102	48	0	16	117	7	108	1e-32	125
rs:WP_043322116	phosphoribosyl-AMP cyclohydrolase [Mycetocola saprophilus].	55.67	97	43	0	16	112	3	99	1e-32	122
rs:WP_006839999	phosphoribosyl-AMP cyclohydrolase [Corynebacterium lipophiloflavum].	61.05	95	37	0	18	112	17	111	1e-32	122
rs:WP_021093702	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Anoxybacillus].	52.94	102	48	0	17	118	2	103	1e-32	125
tr:U1R3S9_9EURY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	53.40	103	48	0	14	116	3	105	1e-32	122
rs:WP_036254492	phosphoribosyl-ATP pyrophosphatase [Megamonas hypermegale].	54.90	102	45	1	11	112	2	102	1e-32	125
rs:WP_025900341	MULTISPECIES: imidazole glycerol phosphate synthase [Prochlorococcus].	52.34	107	50	1	12	117	6	112	1e-32	125
rs:WP_043964829	phosphoribosyl-ATP pyrophosphatase [Anoxybacillus thermarum].	52.94	102	48	0	17	118	2	103	1e-32	125
sp:HIS3_CLOB1	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	58.70	92	38	0	23	114	16	107	1e-32	122
tr:A0A062V6M4_9EURY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	54.81	104	46	1	14	117	2	104	1e-32	122
rs:WP_032077747	phosphoribosyl-AMP cyclohydrolase [Clostridium drakei].	59.55	89	36	0	25	113	21	109	1e-32	122
rs:WP_024879132	phosphoribosyl-AMP cyclohydrolase [Methylosinus sp. LW3].	52.17	115	48	2	19	126	21	135	1e-32	122
rs:WP_031515517	phosphoribosyl-ATP pyrophosphatase [Desulfotomaculum alkaliphilum].	54.55	110	48	2	11	118	1	110	1e-32	125
tr:N9VPQ0_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	55.37	121	48	3	3	117	221	341	1e-32	129
rs:WP_008246184	phosphoribosyl-AMP cyclohydrolase [gamma proteobacterium BDW918].	55.67	97	42	1	18	113	14	110	1e-32	123
rs:WP_022891997	phosphoribosyl-AMP cyclohydrolase [Agromyces subbeticus].	58.06	93	39	0	20	112	16	108	1e-32	122
sp:HIS3_NEIMB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.86	116	56	1	17	131	8	123	1e-32	122
rs:WP_013932330	phosphoribosyl-ATP pyrophosphatase [Pseudothermotoga thermarum].	50.98	102	50	0	13	114	2	103	1e-32	125
rs:WP_012459910	phosphoribosyl-ATP pyrophosphatase [Sulfurihydrogenibium sp. YO3AOP1].	42.98	121	65	2	11	129	1	119	1e-32	125
rs:WP_035049141	phosphoribosyl-ATP pyrophosphatase [Anoxybacillus sp. KU2-6(11)].	52.94	102	48	0	17	118	2	103	1e-32	125
rs:WP_040790244	phosphoribosyl-AMP cyclohydrolase [Nocardia paucivorans].	57.58	99	42	0	18	116	11	109	1e-32	122
rs:WP_046539691	phosphoribosyl-ATP pyrophosphatase [Clostridiales bacterium PH28_bin88].	51.89	106	51	0	17	122	4	109	1e-32	125
rs:WP_032526875	imidazole glycerol phosphate synthase [Prochlorococcus marinus].	50.46	109	53	1	10	117	4	112	1e-32	125
rs:WP_029161398	phosphoribosyl-AMP cyclohydrolase [Clostridium scatologenes].	59.55	89	36	0	25	113	21	109	1e-32	122
rs:WP_028306926	phosphoribosyl-ATP pyrophosphatase [Desulfitibacter alkalitolerans].	53.54	99	46	0	18	116	11	109	1e-32	125
rs:WP_006875265	phosphoribosyl-AMP cyclohydrolase [Anaerotruncus colihominis].	57.29	96	41	0	18	113	7	102	1e-32	122
rs:WP_005929638	phosphoribosyl-ATP pyrophosphatase [Faecalibacterium prausnitzii].	56.57	99	43	0	18	116	3	101	1e-32	125
rs:WP_006920395	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio magneticus].	57.43	101	42	1	23	122	10	110	1e-32	122
rs:WP_005208459	phosphoribosyl-AMP cyclohydrolase [Gordonia sputi].	57.00	100	43	0	15	114	8	107	1e-32	123
rs:WP_045280272	phosphoribosyl-AMP cyclohydrolase [Microbacterium oxydans].	55.67	97	43	0	18	114	11	107	1e-32	122
tr:B4XN79_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	45.24	126	65	2	5	126	2	127	1e-32	122
sp:HIS3_METBF	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	56.07	107	44	2	11	117	9	112	1e-32	122
rs:WP_010645984	phosphoribosyl-AMP cyclohydrolase [endosymbiont of Bathymodiolus sp.].	53.54	99	45	1	16	113	5	103	1e-32	122
rs:WP_040196639	phosphoribosyl-AMP cyclohydrolase [Candidatus Soleaferrea massiliensis].	54.72	106	45	1	11	116	1	103	1e-32	122
tr:A0A0C1QP93_9CYAN	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	55.00	100	44	1	17	115	17	116	1e-32	125
rs:WP_042894536	phosphoribosyl-ATP diphosphatase [Acinetobacter oleivorans].	57.73	97	40	1	18	113	10	106	1e-32	126
rs:WP_046439840	phosphoribosyl-AMP cyclohydrolase [Corynebacterium kutscheri].	60.00	95	37	1	18	112	16	109	1e-32	122
rs:WP_033891146	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium saguini].	58.76	97	40	0	16	112	18	114	1e-32	122
rs:WP_007711377	phosphoribosyl-ATP diphosphatase [[Clostridium] asparagiforme].	49.19	124	55	2	2	117	211	334	1e-32	129
tr:E8QWC0_ISOPI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.59	116	53	2	18	131	22	137	1e-32	123
rs:WP_020419687	phosphoribosyl-AMP cyclohydrolase [Amycolatopsis sp. ATCC 39116].	60.00	95	38	0	18	112	11	105	1e-32	122
sp:HIS3_METCA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.43	103	48	1	18	119	8	110	1e-32	122
rs:WP_022118562	hypothetical protein [Firmicutes bacterium CAG:56].	59.38	96	39	0	18	113	230	325	1e-32	129
rs:WP_036475078	phosphoribosyl-AMP cyclohydrolase [Nesterenkonia sp. AN1].	57.89	95	40	0	18	112	9	103	1e-32	122
sp:HIS3_BRUA1	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.63	114	52	1	19	130	23	136	1e-32	122
rs:WP_023992494	phosphoribosyl-AMP cyclohydrolase [Methanobacterium sp. MB1].	50.48	105	52	0	21	125	13	117	1e-32	122
sp:HIS3_BIFLS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	60.00	95	38	0	18	112	20	114	1e-32	122
rs:WP_025959731	imidazole glycerol phosphate synthase [Prochlorococcus sp. scB245a_519C7].	52.34	107	50	1	12	117	6	112	1e-32	125
rs:WP_018132079	hypothetical protein [Effusibacillus pohliae].	56.57	99	43	0	18	116	4	102	1e-32	125
rs:WP_022319499	hypothetical protein [Dorea sp. CAG:317].	55.24	105	45	1	9	113	222	324	1e-32	129
tr:D8GRA4_CLOLD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	57.78	90	38	0	24	113	16	105	1e-32	122
rs:WP_003831800	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium breve].	58.95	95	39	0	18	112	20	114	1e-32	122
tr:A0A090I4X6_METFO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	50.48	105	52	0	21	125	13	117	1e-32	122
rs:WP_033209388	phosphoribosyl-AMP cyclohydrolase, partial [Gryllotalpicola ginsengisoli].	54.72	106	46	1	9	112	2	107	2e-32	122
rs:WP_029477946	imidazole glycerol phosphate synthase [Deinococcus frigens].	51.67	120	57	1	8	126	3	122	2e-32	125
rs:WP_019004886	hypothetical protein [Cohnella laeviribosi].	57.29	96	41	0	18	113	9	104	2e-32	125
tr:A0A077M9V2_9MICO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	55.79	95	42	0	18	112	26	120	2e-32	122
rs:WP_026882682	phosphoribosyl-AMP cyclohydrolase [Clostridium akagii].	54.26	94	43	0	24	117	15	108	2e-32	122
rs:WP_027503038	phosphoribosyl-AMP cyclohydrolase [Rhodococcus sp. UNC363MFTsu5.1].	57.89	95	40	0	18	112	11	105	2e-32	122
rs:WP_035621759	hypothetical protein, partial [Lachnospiraceae bacterium NC2008].	54.90	102	46	0	13	114	6	107	2e-32	122
rs:WP_038040246	imidazole glycerol phosphate synthase [Thermomicrobiales bacterium KI4].	58.76	97	40	0	16	112	12	108	2e-32	125
rs:WP_021041048	phosphoribosyl-AMP cyclohydrolase [Halonotius sp. J07HN4].	50.96	104	51	0	14	117	9	112	2e-32	122
rs:WP_014441678	phosphoribosyl-AMP cyclohydrolase [Actinoplanes missouriensis].	51.79	112	54	0	1	112	1	112	2e-32	122
rs:WP_022094322	phosphoribosyl-AMP cyclohydrolase [Collinsella sp. CAG:166].	58.33	96	40	0	18	113	10	105	2e-32	122
sp:HIS3_BRUA2	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.63	114	52	1	19	130	3	116	2e-32	122
rs:WP_038070065	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Thermoanaerobacterium].	50.96	104	51	0	18	121	6	109	2e-32	125
rs:WP_039574529	phosphoribosyl-AMP cyclohydrolase [Sphingopyxis sp. Kp5.2].	56.00	100	44	0	19	118	14	113	2e-32	122
gpu:CP009530_1498	Phosphoribosyl-AMP cyclohydrolase [Methanosarcina barkeri 227]	55.14	107	45	2	11	117	2	105	2e-32	122
rs:WP_027518677	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. WSM1417].	52.29	109	50	1	19	125	17	125	2e-32	122
rs:WP_028261213	phosphoribosyl-AMP cyclohydrolase [Verrucomicrobia bacterium SCGC AAA027-I19].	55.88	102	44	1	19	119	29	130	2e-32	122
rs:WP_021009236	phosphoribosyl-AMP cyclohydrolase [Agrococcus pavilionensis].	55.00	100	45	0	18	117	7	106	2e-32	122
rs:WP_022348913	phosphoribosyl-AMP cyclohydrolase [Collinsella sp. CAG:398].	57.29	96	41	0	18	113	6	101	2e-32	121
tr:W9E7G1_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	50.96	104	51	0	18	121	12	115	2e-32	125
rs:WP_025274479	phosphoribosyl-AMP cyclohydrolase [Haloglycomyces albus].	60.00	95	38	0	18	112	13	107	2e-32	122
sp:HIS3_CORGL	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.57	112	51	1	2	112	1	112	2e-32	122
rs:WP_021200600	MULTISPECIES: hypothetical protein [Microbacterium].	58.95	95	39	0	20	114	20	114	2e-32	122
rs:WP_022427899	phosphoribosyl-AMP cyclohydrolase [Ruminococcus sp. CAG:403].	58.00	100	41	1	20	118	15	114	2e-32	122
rs:WP_035056688	phosphoribosyl-AMP cyclohydrolase [Cellulomonas bogoriensis].	57.89	95	40	0	18	112	18	112	2e-32	122
rs:WP_025295637	phosphoribosyl-AMP cyclohydrolase [Trueperella pyogenes].	58.95	95	39	0	18	112	11	105	2e-32	122
rs:WP_045887101	phosphoribosyl-AMP cyclohydrolase [Clostridium sporogenes].	57.61	92	39	0	25	116	18	109	2e-32	122
rs:WP_016188514	phosphoribosyl-AMP cyclohydrolase [Thermobifida fusca].	54.63	108	46	1	8	112	3	110	2e-32	122
rs:WP_043783154	phosphoribosyl-AMP cyclohydrolase [Amycolatopsis rifamycinica].	54.05	111	46	1	15	125	8	113	2e-32	122
rs:WP_027437498	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [Lachnospira multipara].	58.33	96	40	0	18	113	260	355	2e-32	128
tr:M2PT09_9PSEU	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	53.70	108	45	1	18	125	1	103	2e-32	121
rs:WP_024585461	phosphoribosyl-AMP cyclohydrolase [Aliihoeflea sp. 2WW].	52.54	118	52	2	14	127	17	134	2e-32	122
rs:WP_044252920	phosphoribosyl-AMP cyclohydrolase [Isosphaera pallida].	52.59	116	53	2	18	131	2	117	2e-32	122
rs:WP_018503175	phosphoribosyl-AMP cyclohydrolase [Frankia sp. BCU110501].	53.77	106	46	1	10	112	5	110	2e-32	123
rs:WP_018264613	phosphoribosyl-AMP cyclohydrolase [Methylosinus sp. LW4].	53.04	115	47	2	19	126	21	135	2e-32	122
rs:WP_027554592	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. Cp5.3].	56.57	99	43	0	19	117	17	115	2e-32	122
rs:WP_022250377	hypothetical protein [Clostridium nexile CAG:348].	55.24	105	45	1	9	113	222	324	2e-32	128
rs:WP_038265518	phosphoribosyl-ATP pyrophosphatase [[Clostridium] litorale].	49.55	111	56	0	11	121	1	111	2e-32	124
rs:WP_030034856	phosphoribosyl-AMP cyclohydrolase [Clostridium botulinum].	57.61	92	39	0	25	116	18	109	2e-32	121
rs:WP_020622476	phosphoribosyl-AMP cyclohydrolase [Pseudonocardia sp. P2].	57.55	106	41	2	18	120	20	124	2e-32	122
rs:WP_024475695	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. CAL618].	53.70	108	49	1	6	112	14	121	2e-32	122
rs:WP_006671478	phosphoribosyl-AMP cyclohydrolase, partial [Halobiforma nitratireducens].	57.73	97	40	1	11	107	1	96	2e-32	121
rs:WP_029031408	phosphoribosyl-AMP cyclohydrolase [Salinarimonas rosea].	56.48	108	45	1	14	119	19	126	2e-32	122
sp:HIS3_THEFY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	58.95	95	39	0	18	112	16	110	2e-32	122
rs:WP_016949572	phosphoribosyl-ATP pyrophosphatase [Anabaena sp. PCC 7108].	55.56	99	43	1	18	115	18	116	2e-32	124
rs:WP_034875554	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium moukalabense].	53.51	114	48	2	16	129	18	126	2e-32	122
rs:WP_021352405	phosphoribosyl-AMP cyclohydrolase [Corynebacterium pseudodiphtheriticum].	56.84	95	41	0	18	112	20	114	2e-32	122
rs:WP_011826456	phosphoribosyl-ATP pyrophosphatase [Prochlorococcus marinus].	59.41	101	40	1	18	117	12	112	2e-32	125
rs:WP_016314939	phosphoribosyl-AMP cyclohydrolase [Anaerotruncus sp. G3(2012)].	56.86	102	44	0	20	121	7	108	2e-32	121
rs:WP_024824190	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio magneticus].	57.43	101	42	1	23	122	10	110	2e-32	122
rs:WP_033503377	phosphoribosyl-AMP cyclohydrolase, partial [Bifidobacterium subtile].	60.00	95	38	0	18	112	21	115	2e-32	122
rs:WP_019129186	phosphoribosyl-AMP cyclohydrolase [Enorma massiliensis].	57.29	96	41	0	18	113	6	101	2e-32	121
rs:WP_036281921	phosphoribosyl-AMP cyclohydrolase [Methylocystis sp. ATCC 49242].	54.95	111	46	2	19	125	19	129	2e-32	122
rs:WP_006821655	phosphoribosyl-AMP cyclohydrolase [Corynebacterium casei].	58.95	95	38	1	18	112	32	125	2e-32	122
rs:WP_009881404	phosphoribosyl-AMP cyclohydrolase [Brevibacterium linens].	54.74	95	43	0	18	112	21	115	2e-32	122
tr:C7N6K7_SLAHD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.64	97	44	0	18	114	3	99	2e-32	121
rs:WP_006320178	phosphoribosyl-ATP diphosphatase [Anoxybacillus flavithermus].	52.94	102	48	0	17	118	2	103	2e-32	124
tr:J6J768_9RHOB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	53.92	102	46	1	19	119	48	149	2e-32	124
rs:WP_019482417	hypothetical protein [Arthrobacter sp. TB 23].	53.70	108	49	1	6	112	14	121	2e-32	122
rs:WP_043841360	phosphoribosyl-AMP cyclohydrolase, partial [Amycolatopsis taiwanensis].	53.15	111	47	1	15	125	8	113	2e-32	122
rs:WP_027018261	phosphoribosyl-AMP cyclohydrolase [Corynebacterium pseudodiphtheriticum].	56.84	95	41	0	18	112	20	114	2e-32	122
rs:WP_020184582	hypothetical protein [Methylopila sp. 73B].	55.14	107	46	1	19	123	26	132	2e-32	123
tr:A0A087E1Y1_9BIFI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	60.00	95	38	0	18	112	21	115	2e-32	123
tr:D4LT26_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	57.14	98	42	0	16	113	227	324	2e-32	128
tr:B6FRV1_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	55.24	105	45	1	9	113	222	324	2e-32	128
rs:WP_025387435	phosphoribosyl-AMP cyclohydrolase [Corynebacterium casei].	58.95	95	38	1	18	112	32	125	2e-32	122
rs:WP_012576024	phosphoribosyl-ATP pyrophosphatase [Anoxybacillus flavithermus].	51.89	106	51	0	13	118	1	106	2e-32	124
rs:WP_024396297	phosphoribosyl-AMP cyclohydrolase [Streptococcus suis].	59.14	93	38	0	22	114	9	101	2e-32	121
rs:WP_017317260	phosphoribosyl-ATP pyrophosphatase [Mastigocladopsis repens].	56.57	99	42	1	18	115	18	116	2e-32	124
rs:WP_015221722	phosphoribosyl-AMP cyclohydrolase [Cyanobacterium stanieri].	51.79	112	49	2	9	115	3	114	2e-32	124
rs:WP_029869515	phosphoribosyl-AMP cyclohydrolase [Rhizobiales bacterium JGI 001012-O08].	49.21	126	61	2	9	131	13	138	2e-32	122
rs:WP_006077947	phosphoribosyl-AMP cyclohydrolase [Halococcus saccharolyticus].	57.29	96	41	0	18	113	12	107	2e-32	122
rs:WP_036549307	phosphoribosyl-AMP cyclohydrolase [Nitrincola lacisaponensis].	51.35	111	52	2	20	128	11	121	2e-32	122
tr:A6TKT7_ALKMQ	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	55.79	95	42	0	20	114	9	103	2e-32	124
rs:WP_041720282	phosphoribosyl-ATP pyrophosphatase [Alkaliphilus metalliredigens].	55.79	95	42	0	20	114	11	105	2e-32	124
rs:WP_017323961	hypothetical protein [Synechococcus sp. PCC 7336].	54.72	106	47	1	17	121	22	127	2e-32	125
rs:WP_018647138	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium japonicum].	55.56	99	44	0	19	117	17	115	2e-32	122
rs:WP_009516480	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Hydrogenophaga].	52.83	106	46	1	18	119	7	112	2e-32	122
rs:WP_040219756	phosphoribosyl-AMP cyclohydrolase [Collinsella sp. MS5].	57.00	100	43	0	18	117	10	109	2e-32	121
rs:WP_046851212	phosphoribosyl-AMP cyclohydrolase [Nitrosomonas communis].	46.55	116	61	1	16	130	7	122	2e-32	122
tr:A0A069RLR5_CLOLI	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	49.55	111	56	0	11	121	14	124	2e-32	125
rs:WP_003486333	phosphoribosyl-AMP cyclohydrolase [Clostridium sporogenes].	57.61	92	39	0	23	114	12	103	2e-32	121
rs:WP_025946684	imidazole glycerol phosphate synthase [Prochlorococcus sp. scB241_528N20].	51.38	109	52	1	10	117	4	112	2e-32	124
gpu:CP009517_1522	Phosphoribosyl-AMP cyclohydrolase [Methanosarcina barkeri 3]	57.28	103	41	2	11	113	2	101	2e-32	122
rs:WP_037975829	phosphoribosyl-ATP pyrophosphatase [Synergistes jonesii].	53.15	111	51	1	11	120	1	111	2e-32	124
sp:HIS2_NOSS1	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	56.57	99	42	1	18	115	18	116	2e-32	124
tr:A0A0A0B509_9CELL	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.29	105	47	1	9	112	16	120	2e-32	122
rs:WP_027430753	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [Lachnospira multipara].	57.14	98	42	0	16	113	258	355	2e-32	127
rs:WP_025482004	phosphoribosyl-ATP diphosphatase [Clostridiales bacterium VE202-28].	57.73	97	41	0	18	114	239	335	2e-32	128
rs:WP_046842191	imidazole glycerol phosphate synthase [Candidatus Synechococcus spongiarum].	60.82	97	37	1	18	113	9	105	2e-32	124
rs:WP_015717751	phosphoribosyl-ATP pyrophosphatase [Thermus scotoductus].	50.47	107	53	0	13	119	1	107	2e-32	124
sp:HIS3_CLOBK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	57.61	92	39	0	23	114	16	107	2e-32	121
tr:A0A0D6DTT8_9LACT	SubName: Full=Phosphoribosyl-AMP cyclohydrolase HisI {ECO:0000313|EMBL:CEN27234.1};	51.28	117	52	2	2	116	1	114	2e-32	122
rs:WP_023516452	phosphoribosyl-AMP cyclohydrolase [Shinella sp. DD12].	52.21	113	52	1	17	127	22	134	2e-32	122
rs:WP_041088127	phosphoribosyl-ATP pyrophosphatase [Bacillus pumilus].	54.21	107	46	1	16	122	5	108	2e-32	124
rs:WP_008313167	phosphoribosyl-AMP cyclohydrolase [Leptolyngbya sp. PCC 6406].	57.58	99	41	1	18	115	13	111	2e-32	124
rs:WP_035986189	imidazole glycerol phosphate synthase [Leptolyngbya sp. KIOST-1].	50.00	116	57	1	1	115	1	116	2e-32	124
rs:WP_027497285	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Rhodococcus].	55.10	98	44	0	15	112	8	105	2e-32	121
rs:WP_044906715	phosphoribosyl-AMP cyclohydrolase [[Clostridium] innocuum].	56.38	94	41	0	24	117	11	104	2e-32	121
rs:WP_034253891	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium crudilactis].	57.89	95	40	0	18	112	9	103	2e-32	122
rs:WP_027567827	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. URHA0013].	51.38	109	51	1	19	125	17	125	2e-32	122
rs:WP_009632712	phosphoribosyl-AMP cyclohydrolase [Synechocystis sp. PCC 7509].	56.57	99	42	1	16	113	8	106	2e-32	124
rs:WP_010224570	phosphoribosyl-AMP cyclohydrolase [Pseudonocardia sp. P1].	52.89	121	55	2	2	121	1	120	2e-32	121
rs:WP_002964195	phosphoribosyl-AMP cyclohydrolase [Brucella abortus].	51.75	114	53	1	19	130	23	136	2e-32	122
rs:WP_045867779	imidazole glycerol phosphate synthase [Tolypothrix sp. PCC 7601].	48.28	116	59	1	1	115	1	116	2e-32	124
rs:WP_008725569	phosphoribosyl-ATP diphosphatase [Clostridiales bacterium 1_7_47FAA].	57.73	97	41	0	18	114	239	335	2e-32	128
rs:WP_005043166	phosphoribosyl-AMP cyclohydrolase [Halococcus salifodinae].	55.21	96	43	0	18	113	12	107	2e-32	122
rs:WP_040879244	phosphoribosyl-AMP cyclohydrolase [Kaistia granuli].	52.10	119	52	2	6	119	11	129	2e-32	122
rs:WP_044085026	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium gallicum].	58.76	97	40	0	16	112	16	112	2e-32	122
rs:WP_012284026	phosphoribosyl-ATP pyrophosphatase [Heliobacterium modesticaldum].	55.00	100	45	0	18	117	14	113	2e-32	124
rs:WP_039240822	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. MWB30].	57.89	95	40	0	18	112	31	125	2e-32	122
rs:WP_038502439	phosphoribosyl-AMP cyclohydrolase [Rhodoluna lacicola].	48.54	103	53	0	14	116	7	109	2e-32	121
rs:WP_033505718	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium gallinarum].	57.89	95	40	0	18	112	21	115	2e-32	122
rs:WP_043031870	phosphoribosyl-AMP cyclohydrolase [Clostridium botulinum].	57.61	92	39	0	23	114	16	107	2e-32	121
rs:WP_006681083	phosphoribosyl-AMP cyclohydrolase [Actinomyces turicensis].	57.89	95	40	0	18	112	11	105	2e-32	121
rs:WP_044183860	phosphoribosyl-AMP cyclohydrolase [Pirellula staleyi].	52.73	110	47	1	7	116	4	108	2e-32	122
rs:WP_040570920	phosphoribosyl-AMP cyclohydrolase [Methyloversatilis sp. NVD].	53.40	103	46	2	18	118	4	106	2e-32	122
rs:WP_043903102	phosphoribosyl-AMP cyclohydrolase [Kingella kingae].	51.82	110	52	1	11	119	1	110	2e-32	121
rs:WP_013638692	phosphoribosyl-AMP cyclohydrolase [Desulfurobacterium thermolithotrophum].	57.78	90	38	0	24	113	19	108	2e-32	121
rs:WP_024541302	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium choerinum].	57.89	95	40	0	18	112	23	117	2e-32	122
rs:WP_028266823	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. MA-N2].	58.76	97	40	0	16	112	33	129	2e-32	122
rs:WP_013600756	phosphoribosyl-AMP cyclohydrolase [Arthrobacter phenanthrenivorans].	57.73	97	41	0	16	112	37	133	2e-32	122
rs:WP_019892504	hypothetical protein [Allobaculum stercoricanis].	56.38	94	41	0	24	117	11	104	2e-32	121
rs:WP_006790676	phosphoribosyl-ATP pyrophosphatase [Anaeroglobus geminatus].	50.96	104	50	1	11	113	1	104	2e-32	125
rs:WP_010306762	phosphoribosyl-AMP cyclohydrolase [Saccharopolyspora spinosa].	60.00	95	38	0	18	112	12	106	2e-32	121
rs:WP_008860137	phosphoribosyl-ATP pyrophosphatase [Dialister succinatiphilus].	52.00	100	48	0	14	113	5	104	2e-32	124
rs:WP_013174803	phosphoribosyl-ATP pyrophosphatase [Syntrophothermus lipocalidus].	57.29	96	41	0	18	113	9	104	2e-32	124
rs:WP_038029774	imidazole glycerol phosphate synthase [Thermus sp. NMX2.A1].	50.47	107	53	0	13	119	1	107	2e-32	124
rs:WP_045192449	phosphoribosyl-AMP cyclohydrolase [Terrabacter sp. 28].	57.89	95	40	0	18	112	2	96	3e-32	121
rs:WP_022867858	phosphoribosyl-AMP cyclohydrolase [Actinomyces vaccimaxillae].	61.05	95	37	0	18	112	11	105	3e-32	121
rs:WP_003212812	phosphoribosyl-ATP pyrophosphatase [Bacillus pumilus].	53.21	109	48	1	16	124	5	110	3e-32	124
rs:WP_005817209	phosphoribosyl-ATP pyrophosphatase [Desulfitobacterium hafniense].	53.70	108	49	1	18	125	17	123	3e-32	124
rs:WP_033509857	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bifidobacterium].	57.89	95	40	0	18	112	21	115	3e-32	122
rs:WP_032374328	phosphoribosyl-AMP cyclohydrolase [Rhodococcus fascians].	55.10	98	44	0	15	112	8	105	3e-32	121
rs:WP_003826442	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium angulatum].	57.89	95	40	0	18	112	17	111	3e-32	122
rs:WP_028154777	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium japonicum].	52.25	111	50	1	19	126	17	127	3e-32	122
rs:WP_016169414	phosphoribosyl-ATP diphosphatase [Lachnospiraceae bacterium 10-1].	58.33	96	40	0	18	113	230	325	3e-32	128
rs:WP_044418915	phosphoribosyl-ATP diphosphatase [Arcobacter anaerophilus].	51.92	104	50	0	24	127	14	117	3e-32	124
rs:WP_014196726	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Geobacillus].	53.70	108	49	1	15	122	2	108	3e-32	124
rs:WP_027856265	phosphoribosyl-AMP cyclohydrolase [Marinobacterium jannaschii].	59.38	96	39	0	18	113	27	122	3e-32	122
rs:WP_022215196	phosphoribosyl-ATP diphosphatase [Blautia sp. CAG:237].	57.14	98	42	0	16	113	226	323	3e-32	128
rs:WP_029559034	phosphoribosyl-AMP cyclohydrolase [Xanthobacter sp. 91].	52.14	117	53	2	7	120	10	126	3e-32	122
rs:WP_023019278	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Corynebacterium].	56.84	95	41	0	18	112	20	114	3e-32	121
rs:WP_016335961	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Amycolatopsis].	57.73	97	41	0	18	114	11	107	3e-32	121
rs:WP_012613082	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio vulgaris].	54.17	120	52	2	5	123	3	120	3e-32	122
rs:WP_035067419	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio termitidis].	54.17	120	52	2	5	123	3	120	3e-32	122
rs:WP_037226981	phosphoribosyl-AMP cyclohydrolase [Rhodopirellula baltica].	57.43	101	42	1	25	124	21	121	3e-32	121
rs:WP_035105147	phosphoribosyl-AMP cyclohydrolase [Corynebacterium camporealensis].	53.10	113	47	2	5	112	8	119	3e-32	122
rs:WP_038282000	phosphoribosyl-ATP diphosphatase [[Clostridium] celerecrescens].	58.10	105	42	1	9	113	223	325	3e-32	128
rs:WP_007531333	phosphoribosyl-AMP cyclohydrolase [Rhodococcus triatomae].	57.89	95	40	0	18	112	12	106	3e-32	121
rs:WP_035745641	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sanguinis].	56.12	98	43	0	15	112	10	107	3e-32	121
rs:WP_035758268	phosphoribosyl-AMP cyclohydrolase [Granulicoccus phenolivorans].	53.98	113	45	1	24	129	15	127	3e-32	122
rs:WP_022389319	phosphoribosyl-ATP diphosphatase [Ruminococcus obeum CAG:39].	57.14	98	42	0	16	113	227	324	3e-32	128
rs:WP_038958934	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium japonicum].	52.25	111	50	1	19	126	17	127	3e-32	122
tr:F2ARE4_RHOBT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.43	101	42	1	25	124	17	117	3e-32	121
rs:WP_012253709	phosphoribosyl-AMP cyclohydrolase [Methylobacterium extorquens].	56.31	103	43	1	17	117	21	123	3e-32	122
rs:WP_032523795	imidazole glycerol phosphate synthase [Prochlorococcus marinus].	50.46	109	53	1	10	117	4	112	3e-32	124
tr:A0A0A1ZKB4_PROMR	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	50.46	109	53	1	10	117	5	113	3e-32	124
rs:WP_025880916	imidazole glycerol phosphate synthase [Prochlorococcus sp. scB241_527E14].	52.34	107	50	1	12	117	6	112	3e-32	124
rs:WP_030152327	phosphoribosyl-AMP cyclohydrolase [Oerskovia turbata].	58.95	95	39	0	18	112	9	103	3e-32	121
rs:WP_007504532	phosphoribosyl-ATP pyrophosphatase [Caldalkalibacillus thermarum].	55.88	102	45	0	11	112	1	102	3e-32	124
rs:WP_017435699	phosphoribosyl-ATP pyrophosphatase [Geobacillus caldoxylosilyticus].	53.00	100	47	0	13	112	1	100	3e-32	124
rs:WP_038960922	phosphoribosyl-ATP pyrophosphatase [Atribacteria bacterium SCGC AB-164-A22].	49.11	112	56	1	16	126	8	119	3e-32	125
rs:WP_015375790	phosphoribosyl-AMP cyclohydrolase [Geobacillus sp. GHH01].	53.70	108	49	1	15	122	2	108	3e-32	124
tr:A0A0C1DW97_9MICC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.89	95	40	0	18	112	19	113	3e-32	121
rs:WP_009667856	phosphoribosyl-AMP cyclohydrolase [Oxalobacteraceae bacterium IMCC9480].	51.46	103	49	1	16	117	9	111	3e-32	122
rs:WP_023434262	phosphoribosyl-AMP cyclohydrolase [Lutibaculum baratangense].	54.95	111	47	2	19	126	22	132	3e-32	122
rs:WP_016219025	phosphoribosyl-ATP diphosphatase [Dorea sp. 5-2].	52.21	113	52	1	3	113	212	324	3e-32	128
rs:WP_040364568	phosphoribosyl-AMP cyclohydrolase [Brevibacterium senegalense].	57.89	95	40	0	18	112	4	98	3e-32	120
tr:D5WYF4_THIK1	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	50.00	114	56	1	18	130	7	120	3e-32	125
rs:WP_041608566	phosphoribosyl-ATP diphosphatase [Thiomonas intermedia].	50.00	114	56	1	18	130	10	123	3e-32	125
rs:WP_017720077	phosphoribosyl-ATP pyrophosphatase [Oscillatoria sp. PCC 10802].	51.85	108	51	1	9	115	9	116	3e-32	124
rs:WP_046440018	phosphoribosyl-AMP cyclohydrolase [Ruminococcus sp. N15.MGS-57].	52.43	103	49	0	20	122	15	117	3e-32	121
rs:WP_039181653	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. WP8].	54.21	107	46	1	16	122	5	108	3e-32	124
rs:WP_031596454	phosphoribosyl-AMP cyclohydrolase [Ferrovum myxofaciens].	54.46	101	45	1	18	117	16	116	3e-32	122
rs:WP_014912843	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Nocardiopsis].	56.84	95	41	0	18	112	14	108	3e-32	121
rs:WP_021321640	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Geobacillus].	53.70	108	49	1	15	122	2	108	3e-32	124
sp:HIS2_PROMM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	59.41	101	40	1	18	117	12	112	3e-32	124
rs:WP_005840115	phosphoribosyl-ATP pyrophosphatase [Mitsuokella multacida].	53.85	104	47	1	9	112	6	108	3e-32	125
rs:WP_027560030	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium].	55.56	99	44	0	19	117	17	115	3e-32	122
rs:WP_011932655	phosphoribosyl-ATP pyrophosphatase [Synechococcus sp. WH 7803].	59.79	97	38	1	18	113	12	108	3e-32	124
rs:WP_041592181	phosphoribosyl-ATP pyrophosphatase [Thermoanaerobacterium xylanolyticum].	52.48	101	48	0	18	118	6	106	3e-32	124
tr:N2BCT2_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	50.00	118	57	1	16	131	226	343	3e-32	128
rs:WP_029259246	phosphoribosyl-AMP cyclohydrolase [Microbacterium sp. Cr-K29].	58.95	95	39	0	20	114	20	114	3e-32	121
rs:WP_029981708	imidazole glycerol phosphate synthase, partial [Prochlorococcus sp. scB243_497N18].	50.46	109	53	1	10	117	5	113	3e-32	123
rs:WP_007322191	phosphoribosyl-AMP cyclohydrolase [Gordonia araii].	57.73	97	41	0	18	114	22	118	3e-32	121
rs:WP_017197407	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. M2012083].	55.67	97	43	0	16	112	29	125	3e-32	122
rs:WP_040834591	phosphoribosyl-AMP cyclohydrolase [Nocardia brevicatena].	57.89	95	40	0	18	112	11	105	3e-32	121
rs:WP_035266422	phosphoribosyl-AMP cyclohydrolase [Ahrensia sp. 13_GOM-1096m].	50.44	113	51	2	19	126	29	141	3e-32	122
rs:WP_035732074	phosphoribosyl-AMP cyclohydrolase [Frankia sp. Allo2].	56.84	95	41	0	18	112	16	110	3e-32	122
rs:WP_012122780	phosphoribosyl-ATP pyrophosphatase [Roseiflexus castenholzii].	57.29	96	41	0	18	113	1	96	3e-32	124
rs:WP_034801787	phosphoribosyl-AMP cyclohydrolase [Intrasporangium oryzae].	58.95	95	39	0	18	112	19	113	3e-32	121
rs:WP_004869806	phosphoribosyl-ATP diphosphatase [Acinetobacter gerneri].	56.70	97	41	1	18	113	10	106	3e-32	125
rs:WP_036027717	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium yuanmingense].	53.54	99	46	0	19	117	17	115	3e-32	122
rs:WP_005324611	phosphoribosyl-AMP cyclohydrolase [Corynebacterium pseudogenitalium].	58.95	95	38	1	18	112	17	110	3e-32	121
rs:WP_024789464	phosphoribosyl-ATP diphosphatase [Lebetimonas sp. JH292].	52.88	104	47	1	23	126	11	112	3e-32	124
rs:WP_018152106	hypothetical protein [Leeia oryzae].	47.41	116	60	1	16	130	9	124	3e-32	122
rs:WP_005963847	phosphoribosyl-AMP cyclohydrolase [Actinomyces cardiffensis].	55.79	95	42	0	18	112	11	105	3e-32	121
tr:A0A078BIK9_9BURK	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	50.00	114	56	1	18	130	7	120	3e-32	125
rs:WP_013166821	phosphoribosyl-AMP cyclohydrolase [Starkeya novella].	56.88	109	45	1	14	120	19	127	3e-32	122
rs:WP_024787265	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Lebetimonas].	52.88	104	47	1	23	126	11	112	3e-32	124
rs:WP_028848120	phosphoribosyl-AMP cyclohydrolase [Thermocrispum agreste].	52.54	118	50	2	9	125	2	114	3e-32	121
rs:WP_044738007	phosphoribosyl-AMP cyclohydrolase [Bacillus mycoides].	55.21	96	43	0	18	113	28	123	3e-32	122
rs:WP_021951641	phosphoribosyl-AMP cyclohydrolase [Clostridium sp. CAG:678].	54.08	98	45	0	20	117	9	106	3e-32	121
rs:WP_015831270	phosphoribosyl-AMP cyclohydrolase [Methylotenera mobilis].	49.11	112	56	1	20	130	9	120	3e-32	121
rs:WP_028493884	imidazole glycerol phosphate synthase [Thermus antranikianii].	50.47	107	53	0	13	119	1	107	3e-32	124
rs:WP_040468243	hypothetical protein [Eubacterium plexicaudatum].	50.00	118	57	1	16	131	227	344	3e-32	128
rs:WP_022494092	phosphoribosyl-AMP cyclohydrolase [Ruminococcus sp. CAG:624].	52.94	102	48	0	20	121	19	120	3e-32	121
rs:WP_036374985	phosphoribosyl-ATP pyrophosphatase [Mitsuokella jalaludinii].	49.58	119	59	1	13	131	8	125	3e-32	124
rs:WP_025914390	imidazole glycerol phosphate synthase [Prochlorococcus sp. scB245a_520K10].	49.54	109	54	1	10	117	4	112	3e-32	124
tr:W9G9M3_9MICO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	58.95	95	39	0	18	112	16	110	3e-32	121
tr:A5ZQI0_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	57.14	98	42	0	16	113	227	324	3e-32	127
rs:WP_013146378	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Geobacillus].	53.70	108	49	1	15	122	2	108	3e-32	124
rs:WP_036734889	phosphoribosyl-AMP cyclohydrolase [Peptococcaceae bacterium SCADC1_2_3].	54.21	107	48	1	14	119	5	111	3e-32	121
rs:WP_017816579	phosphoribosyl-AMP cyclohydrolase [Acinetobacter baumannii].	57.29	96	41	0	18	113	28	123	4e-32	122
rs:WP_012082914	phosphoribosyl-ATP pyrophosphatase [Nitratiruptor sp. SB155-2].	55.79	95	42	0	25	119	12	106	4e-32	124
rs:WP_019928149	phosphoribosyl-AMP cyclohydrolase [Nocardia sp. BMG111209].	56.84	95	41	0	18	112	11	105	4e-32	121
tr:D6CL61_THIA3	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	50.00	114	56	1	18	130	7	120	4e-32	125
tr:F6BH60_THEXL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	52.48	101	48	0	18	118	12	112	4e-32	124
rs:WP_011232540	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Geobacillus].	53.70	108	49	1	15	122	2	108	4e-32	124
rs:WP_033089995	phosphoribosyl-AMP cyclohydrolase [Nocardia seriolae].	57.58	99	42	0	18	116	12	110	4e-32	121
rs:WP_018778634	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. 161MFSha2.1].	57.89	95	40	0	18	112	31	125	4e-32	122
rs:WP_045252005	phosphoribosyl-AMP cyclohydrolase [Microbacterium azadirachtae].	53.92	102	47	0	11	112	6	107	4e-32	121
rs:WP_034835727	phosphoribosyl-AMP cyclohydrolase [[Clostridium] cellulosi].	54.26	94	43	0	20	113	5	98	4e-32	120
rs:WP_035045788	phosphoribosyl-AMP cyclohydrolase [Caulobacter henricii].	52.78	108	49	1	14	119	19	126	4e-32	121
rs:WP_027583219	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. Ai1a-2].	52.48	101	48	0	19	119	17	117	4e-32	122
rs:WP_022410207	phosphoribosyl-AMP cyclohydrolase [Ruminococcus sp. CAG:330].	52.88	104	49	0	11	114	4	107	4e-32	121
rs:WP_003051351	phosphoribosyl-AMP cyclohydrolase [Sphingopyxis sp. MC1].	54.37	103	46	1	19	120	14	116	4e-32	121
rs:WP_015771495	phosphoribosyl-AMP cyclohydrolase [Jonesia denitrificans].	56.31	103	45	0	18	120	16	118	4e-32	121
rs:WP_041609156	phosphoribosyl-ATP diphosphatase [Thiomonas arsenitoxydans].	50.00	114	56	1	18	130	10	123	4e-32	125
rs:WP_008307361	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Haloarcula].	56.00	100	44	0	18	117	6	105	4e-32	121
rs:WP_038034389	phosphoribosyl-AMP cyclohydrolase [Thermopetrobacter sp. TC1].	53.64	110	49	1	14	121	20	129	4e-32	122
rs:WP_044987801	hypothetical protein [Tyzzerella nexilis].	55.24	105	45	1	9	113	211	313	4e-32	127
rs:WP_007189465	phosphoribosyl-AMP cyclohydrolase [Haloarcula californiae].	56.00	100	44	0	18	117	6	105	4e-32	121
rs:WP_024392399	phosphoribosyl-AMP cyclohydrolase [Streptococcus suis].	59.14	93	38	0	22	114	9	101	4e-32	120
tr:A0A0A8NAJ7_BIFLI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	60.00	95	38	0	18	112	49	143	4e-32	122
rs:WP_026605729	phosphoribosyl-AMP cyclohydrolase [Methylocapsa acidiphila].	50.41	121	51	3	7	123	15	130	4e-32	121
rs:WP_005278556	phosphoribosyl-AMP cyclohydrolase [Corynebacterium sp. KPL1986].	57.89	95	39	1	18	112	17	110	4e-32	121
rs:WP_044879275	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. IHBB 10380].	53.54	99	46	0	18	116	18	116	4e-32	124
rs:WP_034877311	phosphoribosyl-AMP cyclohydrolase [Endozoicomonas montiporae].	54.81	104	46	1	17	119	6	109	4e-32	121
rs:WP_016865536	phosphoribosyl-ATP pyrophosphatase [Fischerella muscicola].	56.57	99	42	1	18	115	18	116	4e-32	124
rs:WP_012546303	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Thermodesulfovibrio].	53.47	101	46	1	18	117	6	106	4e-32	120
rs:WP_040316427	phosphoribosyl-AMP cyclohydrolase [Actinomyces europaeus].	54.87	113	50	1	1	112	1	113	4e-32	121
rs:WP_007547147	phosphoribosyl-ATP pyrophosphatase [Sulfurihydrogenibium yellowstonense].	42.98	121	65	2	11	129	1	119	4e-32	123
rs:WP_037463114	phosphoribosyl-AMP cyclohydrolase [Smithella sp. F21].	55.10	98	43	1	23	119	10	107	4e-32	121
rs:WP_022300527	phosphoribosyl-AMP cyclohydrolase [Erysipelotrichaceae bacterium CAG:64].	56.38	94	41	0	24	117	11	104	4e-32	120
rs:WP_020309954	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Megasphaera].	53.12	96	45	0	18	113	9	104	4e-32	124
tr:G4MCD1_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.38	105	49	1	18	121	13	117	4e-32	121
rs:WP_034658179	phosphoribosyl-AMP cyclohydrolase [Corynebacterium sp. KPL1818].	57.89	95	39	1	18	112	22	115	4e-32	121
rs:WP_045677623	phosphoribosyl-AMP cyclohydrolase [Desulfatitalea sp. BRH_c12].	54.05	111	44	3	9	118	3	107	4e-32	121
rs:WP_018687618	hypothetical protein [Ahrensia kielensis].	51.33	113	50	2	19	126	29	141	4e-32	122
rs:WP_045730486	phosphoribosyl-AMP cyclohydrolase [Arthrobacter chlorophenolicus].	56.70	97	42	0	16	112	24	120	4e-32	121
rs:WP_046142484	phosphoribosyl-AMP cyclohydrolase [Devosia soli].	53.04	115	50	2	19	129	24	138	4e-32	122
rs:WP_034245760	phosphoribosyl-AMP cyclohydrolase [Actinotalea fermentans].	58.95	95	39	0	18	112	13	107	4e-32	121
rs:WP_022067432	phosphoribosyl-ATP pyrophosphohydrolase [Blautia sp. CAG:257].	57.14	98	42	0	16	113	227	324	4e-32	127
rs:WP_035634008	hypothetical protein [Lachnospiraceae bacterium ND2006].	57.29	96	41	0	18	113	241	336	4e-32	127
rs:WP_044925625	phosphoribosyl-ATP diphosphatase [[Ruminococcus] obeum].	57.14	98	42	0	16	113	218	315	4e-32	127
tr:C4NAN7_BURVI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	49.58	119	52	2	11	121	1	119	4e-32	121
rs:WP_016696032	phosphoribosyl-AMP cyclohydrolase [Rhodococcus rhodochrous].	54.72	106	48	0	18	123	13	118	4e-32	121
rs:WP_045572682	phosphoribosyl-ATP pyrophosphatase [Desulfosporosinus sp. I2].	49.11	112	56	1	13	123	17	128	4e-32	124
rs:WP_036260283	phosphoribosyl-AMP cyclohydrolase [Methylocapsa aurea].	50.86	116	52	2	6	116	2	117	4e-32	121
rs:WP_017534063	phosphoribosyl-AMP cyclohydrolase [Nocardiopsis alba].	56.84	95	41	0	18	112	14	108	4e-32	120
rs:WP_022263758	phosphoribosyl-AMP cyclohydrolase [Clostridium sp. CAG:352].	56.38	94	41	0	20	113	13	106	4e-32	120
rs:WP_035102750	phosphoribosyl-AMP cyclohydrolase [Devosia sp. LC5].	54.13	109	48	1	19	125	25	133	4e-32	122
rs:WP_015756386	phosphoribosyl-ATP pyrophosphatase [Desulfotomaculum acetoxidans].	56.44	101	44	0	13	113	4	104	4e-32	124
rs:WP_009454133	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Fischerella].	56.57	99	42	1	18	115	18	116	4e-32	124
rs:WP_018170765	hypothetical protein [Microbacterium sp. 292MF].	57.73	97	41	0	16	112	10	106	4e-32	121
rs:WP_020179022	hypothetical protein [Methylopila sp. M107].	54.10	122	46	3	7	123	16	132	4e-32	122
rs:WP_025037096	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. DOA9].	54.55	99	45	0	19	117	17	115	4e-32	121
rs:WP_016305864	phosphoribosyl-ATP diphosphatase [Lachnospiraceae bacterium A2].	56.19	105	44	1	9	113	221	323	5e-32	127
rs:WP_022916460	phosphoribosyl-AMP cyclohydrolase [Ruania albidiflava].	61.05	95	37	0	18	112	16	110	5e-32	121
rs:WP_044892982	phosphoribosyl-ATP pyrophosphatase [Bacillus alveayuensis].	55.79	95	42	0	18	112	6	100	5e-32	123
rs:WP_033142115	phosphoribosyl-AMP cyclohydrolase [Blautia producta].	55.32	94	42	0	20	113	7	100	5e-32	120
rs:WP_034654114	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Corynebacterium].	57.89	95	39	1	18	112	22	115	5e-32	121
rs:WP_025931580	MULTISPECIES: imidazole glycerol phosphate synthase [Prochlorococcus].	51.38	109	52	1	10	117	4	112	5e-32	124
rs:WP_034507808	phosphoribosyl-AMP cyclohydrolase [Actinomyces sp. S4-C9].	58.76	97	40	0	16	112	15	111	5e-32	121
rs:WP_044541336	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. LTSP885].	49.56	113	57	0	19	131	19	131	5e-32	121
rs:WP_028991073	phosphoribosyl-ATP pyrophosphatase [Thermacetogenium phaeum].	56.25	96	42	0	17	112	7	102	5e-32	123
tr:K1Z8Q5_9BACT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	55.77	104	43	2	17	117	3	106	5e-32	121
tr:S2VUQ4_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	60.00	95	38	0	18	112	17	111	5e-32	121
rs:WP_017485591	phosphoribosyl-AMP cyclohydrolase [Methylobacterium sp. MB200].	57.28	103	42	1	17	117	21	123	5e-32	121
tr:A0A0C2LJ22_9CYAN	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	53.47	101	46	1	18	117	18	118	5e-32	124
rs:WP_034634357	phosphoribosyl-AMP cyclohydrolase [Cellulomonas cellasea].	56.84	95	41	0	18	112	9	103	5e-32	121
rs:WP_043703697	phosphoribosyl-AMP cyclohydrolase [Tepidimonas taiwanensis].	53.00	100	43	1	18	113	7	106	5e-32	121
tr:A0A093AR05_9PSEU	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:AJK57780.1};	56.70	97	42	0	18	114	11	107	5e-32	120
rs:WP_009004279	imidazole glycerol phosphate synthase [Clostridium sp. D5].	55.24	105	45	1	9	113	222	324	5e-32	127
rs:WP_039690305	phosphoribosyl-AMP cyclohydrolase [Coriobacteriaceae bacterium 68-1-3].	56.25	96	42	0	18	113	10	105	5e-32	120
rs:WP_004892530	phosphoribosyl-AMP cyclohydrolase [Anoxybacillus flavithermus].	52.94	102	48	0	17	118	2	103	5e-32	123
rs:WP_002115091	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Acinetobacter calcoaceticus/baumannii complex].	56.70	97	41	1	18	113	10	106	5e-32	124
rs:WP_042462927	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. FF4].	54.00	100	46	0	13	112	1	100	5e-32	123
rs:WP_015229793	phosphoribosyl-ATP pyrophosphohydrolase [Dactylococcopsis salina].	56.70	97	41	1	20	115	15	111	5e-32	123
rs:WP_013897362	phosphoribosyl-AMP cyclohydrolase [Methanosalsum zhilinae].	52.38	105	46	1	17	117	2	106	5e-32	120
rs:WP_029080131	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. th.b2].	47.54	122	61	1	10	131	13	131	5e-32	121
rs:WP_036915629	MULTISPECIES: imidazole glycerol phosphate synthase [Prochlorococcus].	60.00	100	39	1	18	116	12	111	5e-32	124
rs:WP_019429777	phosphoribosyl-AMP cyclohydrolase [Limnohabitans sp. Rim47].	47.01	117	58	1	18	130	7	123	5e-32	121
sp:HIS3_CORGB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.68	112	52	1	2	112	1	112	5e-32	120
rs:WP_033517452	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium cuniculi].	56.84	95	41	0	18	112	21	115	5e-32	121
rs:WP_036748283	hypothetical protein, partial [Peptococcaceae bacterium SCADC1_2_3].	54.00	100	46	0	14	113	5	104	5e-32	120
rs:WP_026647326	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium minimum].	58.95	95	39	0	18	112	28	122	5e-32	121
rs:WP_028270782	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. UNC362MFTsu5.1].	57.89	95	40	0	18	112	21	115	5e-32	121
rs:WP_039813790	phosphoribosyl-ATP pyrophosphatase [Jeotgalibacillus sp. D5].	51.00	100	49	0	13	112	1	100	5e-32	123
rs:WP_010150936	phosphoribosyl-AMP cyclohydrolase [SAR324 cluster bacterium JCVI-SC AAA005].	51.92	104	48	1	10	113	6	107	5e-32	120
rs:WP_024964069	phosphoribosyl-AMP cyclohydrolase [Trueperella pyogenes].	58.95	95	39	0	18	112	11	105	5e-32	120
rs:WP_010752709	phosphoribosyl-ATP diphosphatase [Enterococcus asini].	55.79	95	42	0	18	112	7	101	5e-32	123
rs:WP_024367457	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. TB 26].	58.95	95	39	0	18	112	27	121	5e-32	121
rs:WP_026875662	phosphoribosyl-AMP cyclohydrolase [Jiangella gansuensis].	55.79	95	42	0	18	112	12	106	5e-32	120
rs:WP_009362300	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Anoxybacillus].	54.64	97	44	0	17	113	2	98	5e-32	123
rs:WP_036267385	imidazole glycerol phosphate synthase [Mastigocoleus testarum].	51.33	113	45	2	13	115	9	121	5e-32	124
rs:WP_043592775	phosphoribosyl-AMP cyclohydrolase [Frigoribacterium sp. MEB024].	58.51	94	39	0	19	112	18	111	5e-32	121
rs:WP_014520633	phosphoribosyl-AMP cyclohydrolase [Clostridium botulinum].	58.24	91	38	0	23	113	16	106	5e-32	120
rs:WP_005272550	phosphoribosyl-AMP cyclohydrolase [Arthrobacter crystallopoietes].	58.95	95	39	0	18	112	28	122	5e-32	121
rs:WP_015950928	phosphoribosyl-AMP cyclohydrolase [Methylobacterium extorquens].	56.31	103	43	1	17	117	21	123	5e-32	121
rs:WP_013400006	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Geobacillus].	50.50	101	50	0	14	114	2	102	5e-32	123
rs:WP_037199043	phosphoribosyl-AMP cyclohydrolase [Rhodopirellula baltica].	57.43	101	42	1	25	124	21	121	5e-32	121
rs:WP_017544541	phosphoribosyl-AMP cyclohydrolase [Nocardiopsis prasina].	57.89	95	40	0	18	112	14	108	5e-32	120
rs:WP_028933044	phosphoribosyl-AMP cyclohydrolase [Pseudonocardia spinosispora].	57.89	95	40	0	18	112	11	105	5e-32	120
rs:WP_026642228	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium tsurumiense].	56.70	97	42	0	16	112	20	116	5e-32	121
rs:WP_018400700	phosphoribosyl-ATP pyrophosphatase [filamentous cyanobacterium ESFC-1].	57.73	97	40	1	18	113	16	112	5e-32	123
rs:WP_009358179	phosphoribosyl-AMP cyclohydrolase [Arthrobacter nitrophenolicus].	56.70	97	42	0	16	112	37	133	5e-32	121
rs:WP_016214914	phosphoribosyl-ATP diphosphatase [Eubacterium sp. 14-2].	56.19	105	44	1	9	113	221	323	5e-32	127
rs:WP_011373489	phosphoribosyl-ATP pyrophosphatase [Sulfurimonas denitrificans].	52.43	103	49	0	25	127	15	117	5e-32	124
tr:D1NTQ1_9BIFI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	58.76	97	40	0	16	112	38	134	5e-32	121
rs:WP_018772467	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Arthrobacter].	60.00	95	38	0	18	112	40	134	5e-32	121
gp:CP000708_959	phosphoribosyl-AMP cyclohydrolase [Brucella ovis ATCC 25840]	51.30	115	54	1	19	131	3	117	5e-32	120
rs:WP_007223960	phosphoribosyl-AMP cyclohydrolase [marine gamma proteobacterium HTCC2143].	48.21	112	57	1	20	130	20	131	5e-32	121
tr:K5EB29_RHOBT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.43	101	42	1	25	124	17	117	5e-32	120
rs:WP_003248082	phosphoribosyl-ATP pyrophosphatase [Geobacillus thermoglucosidasius].	50.50	101	50	0	14	114	2	102	5e-32	123
rs:WP_008656760	phosphoribosyl-AMP cyclohydrolase [Rhodopirellula europaea].	57.43	101	42	1	25	124	21	121	5e-32	120
rs:WP_023497733	phosphoribosyl-AMP cyclohydrolase [uncultured archaeon A07HR67].	56.25	96	42	0	18	113	12	107	5e-32	120
tr:A0A087BNK5_9BIFI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	58.95	95	39	0	18	112	37	131	5e-32	121
rs:WP_029624701	phosphoribosyl-AMP cyclohydrolase [Sphingomonas sp. KC8].	55.79	95	42	0	19	113	14	108	5e-32	120
rs:WP_036301892	phosphoribosyl-AMP cyclohydrolase [Methylotenera sp. L2L1].	51.96	102	48	1	20	120	9	110	6e-32	121
rs:WP_015822737	phosphoribosyl-AMP cyclohydrolase [Methylobacterium extorquens].	55.34	103	44	1	17	117	21	123	6e-32	121
rs:WP_043969313	phosphoribosyl-AMP cyclohydrolase [Micromonospora carbonacea].	55.67	97	43	0	18	114	37	133	6e-32	121
tr:K4LE20_THEPS	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	56.25	96	42	0	17	112	19	114	6e-32	123
tr:A0A0B5GTN9_9EURY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	56.00	100	44	0	18	117	6	105	6e-32	120
rs:WP_032101181	phosphoribosyl-ATP pyrophosphatase [Anoxybacillus flavithermus].	50.00	106	53	0	13	118	1	106	6e-32	123
rs:WP_044898843	phosphoribosyl-ATP pyrophosphatase [Aeribacillus pallidus].	52.88	104	49	0	18	121	10	113	6e-32	123
rs:WP_046471630	phosphoribosyl-AMP cyclohydrolase [Allosalinactinospora lopnorensis].	58.95	95	39	0	18	112	25	119	6e-32	121
rs:WP_023593893	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pandoraea].	51.43	105	50	1	18	121	9	113	6e-32	121
sp:HIS3_RHOBA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	57.43	101	42	1	25	124	21	121	6e-32	120
rs:WP_041750861	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. BTAi1].	50.45	111	51	1	19	125	17	127	6e-32	121
rs:WP_016225291	phosphoribosyl-ATP diphosphatase [Lachnospiraceae bacterium 3-2].	56.19	105	44	1	9	113	222	324	6e-32	127
rs:WP_022397661	phosphoribosyl-AMP cyclohydrolase [Akkermansia sp. CAG:344].	55.77	104	45	1	19	121	29	132	6e-32	122
rs:WP_005037082	phosphoribosyl-ATP diphosphatase [Holophaga foetida].	58.59	99	40	1	14	112	2	99	6e-32	123
rs:WP_006012574	phosphoribosyl-AMP cyclohydrolase [Brucella ovis].	51.75	114	53	1	19	130	23	136	6e-32	121
tr:A0A080M9Y6_9PROT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	56.70	97	41	1	18	113	14	110	6e-32	121
rs:WP_028175875	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium].	50.46	109	52	1	19	125	17	125	6e-32	121
rs:WP_025956575	MULTISPECIES: imidazole glycerol phosphate synthase [Prochlorococcus].	50.46	109	53	1	10	117	4	112	6e-32	123
rs:WP_042185923	phosphoribosyl-AMP cyclohydrolase [Kibdelosporangium sp. MJ126-NF4].	61.05	95	37	0	18	112	11	105	6e-32	120
rs:WP_014494350	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium japonicum].	51.35	111	51	1	19	126	17	127	6e-32	121
rs:WP_034947769	phosphoribosyl-AMP cyclohydrolase [Candidatus Accumulibacter sp. SK-02].	56.70	97	41	1	18	113	7	103	6e-32	120
rs:WP_043285070	phosphoribosyl-AMP cyclohydrolase [Burkholderia oxyphila].	49.15	118	59	1	1	117	1	118	6e-32	121
rs:WP_038935996	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium japonicum].	51.35	111	51	1	19	126	17	127	6e-32	121
rs:WP_011531023	phosphoribosyl-ATP pyrophosphatase [Deinococcus geothermalis].	54.55	110	49	1	18	126	7	116	6e-32	123
rs:WP_033402625	phosphoribosyl-AMP cyclohydrolase [Endozoicomonas elysicola].	54.90	102	45	1	18	118	10	111	6e-32	121
rs:WP_042573293	phosphoribosyl-AMP cyclohydrolase [Rhodococcus sp. MEB064].	55.67	97	43	0	16	112	12	108	6e-32	120
rs:WP_025949872	phosphoribosyl-ATP pyrophosphatase [Geobacillus thermocatenulatus].	53.70	108	49	1	15	122	2	108	6e-32	123
rs:WP_038021436	phosphoribosyl-AMP cyclohydrolase [Tatumella morbirosei].	46.22	119	62	1	1	117	4	122	6e-32	121
tr:A0A085ETW9_9RHIZ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.13	109	48	1	19	125	33	141	6e-32	121
rs:WP_024820580	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. 31Y].	55.67	97	43	0	16	112	29	125	6e-32	121
rs:WP_044585863	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. LTSPM299].	50.44	113	56	0	19	131	21	133	6e-32	121
rs:WP_040622148	phosphoribosyl-AMP cyclohydrolase [Smithella sp. ME-1].	56.31	103	43	2	24	125	11	112	6e-32	120
rs:WP_012011364	phosphoribosyl-ATP pyrophosphatase [Bacillus pumilus].	54.21	107	46	1	18	124	7	110	6e-32	123
rs:WP_002567576	phosphoribosyl-ATP diphosphatase [[Clostridium] bolteae].	56.44	101	44	0	18	118	239	339	6e-32	127
rs:WP_028038128	phosphoribosyl-AMP cyclohydrolase [Caulobacter sp. URHA0033].	55.77	104	44	1	17	118	23	126	6e-32	121
rs:WP_014162981	phosphoribosyl-ATP pyrophosphatase [Thermovirga lienii].	52.88	104	49	0	11	114	1	104	6e-32	123
rs:WP_042220470	phosphoribosyl-ATP pyrophosphatase [Oceanobacillus manasiensis].	47.75	111	58	0	11	121	1	111	6e-32	123
rs:WP_025965492	imidazole glycerol phosphate synthase [Prochlorococcus sp. scB243_496M6].	50.46	109	53	1	10	117	4	112	6e-32	123
tr:U5VXF5_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.29	105	47	1	9	112	6	110	7e-32	120
rs:WP_028925767	phosphoribosyl-AMP cyclohydrolase [Pseudonocardia acaciae].	58.95	95	39	0	18	112	11	105	7e-32	120
rs:WP_027404661	imidazole glycerol phosphate synthase [Aphanizomenon flos-aquae].	54.55	99	44	1	18	115	18	116	7e-32	123
rs:WP_027481603	imidazole glycerol phosphate synthase [Deinococcus pimensis].	52.21	113	52	1	9	119	2	114	7e-32	123
rs:WP_022876455	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. PAO19].	58.95	95	39	0	18	112	25	119	7e-32	120
rs:WP_004899076	phosphoribosyl-AMP cyclohydrolase [Acinetobacter brisouii].	54.72	106	46	2	18	121	10	115	7e-32	124
tr:U1MZT2_9EURY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	51.40	107	51	1	11	117	1	106	7e-32	120
rs:WP_042226365	phosphoribosyl-AMP cyclohydrolase [Kingella kingae].	50.91	110	53	1	11	119	1	110	7e-32	120
rs:WP_026049718	phosphoribosyl-AMP cyclohydrolase [Microbacterium barkeri].	56.70	97	42	0	18	114	16	112	7e-32	120
rs:WP_040898346	imidazole glycerol phosphate synthase [Xenococcus sp. PCC 7305].	55.56	99	43	1	18	115	25	123	7e-32	123
rs:WP_042850026	imidazole glycerol phosphate synthase [Prochlorococcus sp. MIT 0604].	50.46	109	53	1	10	117	4	112	7e-32	123
rs:WP_011376134	phosphoribosyl-ATP pyrophosphatase [Prochlorococcus marinus].	49.54	109	54	1	10	117	4	112	7e-32	123
rs:WP_025952532	imidazole glycerol phosphate synthase [Prochlorococcus sp. scB243_495P20].	51.40	107	51	1	12	117	6	112	7e-32	123
rs:WP_017615868	phosphoribosyl-AMP cyclohydrolase [Nocardiopsis salina].	56.84	95	41	0	18	112	14	108	7e-32	120
tr:Q2SUA9_BURTA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00006950}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	50.86	116	53	2	17	128	147	262	7e-32	124
rs:WP_008669810	phosphoribosyl-AMP cyclohydrolase [Rhodopirellula europaea].	57.43	101	42	1	25	124	21	121	7e-32	120
rs:WP_014558741	phosphoribosyl-AMP cyclohydrolase [Corynebacterium pseudotuberculosis].	60.00	95	37	1	18	112	19	112	7e-32	120
rs:WP_029674684	imidazole glycerol phosphate synthase [Butyrivibrio sp. VCB2006].	51.46	103	50	0	12	114	7	109	7e-32	123
rs:WP_013110587	phosphoribosyl-AMP cyclohydrolase [Planctomyces limnophilus].	55.14	107	47	1	20	125	12	118	7e-32	120
rs:WP_026407073	phosphoribosyl-AMP cyclohydrolase [Actinomyces gerencseriae].	57.73	97	41	0	16	112	7	103	7e-32	120
sp:HIS3_ARTAT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	55.67	97	43	0	16	112	29	125	7e-32	121
rs:WP_043578399	phosphoribosyl-AMP cyclohydrolase [Chromobacterium subtsugae].	50.00	114	56	1	18	130	7	120	7e-32	120
rs:WP_021478413	phosphoribosyl-AMP cyclohydrolase [Pseudogulbenkiania ferrooxidans].	51.92	104	49	1	18	120	7	110	7e-32	120
rs:WP_018213584	phosphoribosyl-ATP pyrophosphatase [Desulfitobacterium hafniense].	53.70	108	49	1	18	125	17	123	7e-32	123
rs:WP_014688772	phosphoribosyl-AMP cyclohydrolase [Actinoplanes sp. SE50/110].	57.29	96	41	0	18	113	16	111	7e-32	120
rs:WP_036044038	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium yuanmingense].	53.54	99	46	0	19	117	17	115	7e-32	121
rs:WP_005943640	phosphoribosyl-ATP pyrophosphatase [Faecalibacterium prausnitzii].	55.00	100	45	0	17	116	2	101	7e-32	123
rs:WP_041299648	phosphoribosyl-AMP cyclohydrolase, partial [Ilumatobacter coccineus].	59.79	97	38	1	18	113	17	113	7e-32	120
rs:WP_036010523	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium yuanmingense].	53.54	99	46	0	19	117	17	115	7e-32	121
rs:WP_002591743	phosphoribosyl-ATP diphosphatase [[Clostridium] clostridioforme].	56.44	101	44	0	18	118	239	339	7e-32	127
rs:WP_018304945	phosphoribosyl-ATP pyrophosphatase [Desulfitobacterium hafniense].	53.70	108	49	1	18	125	17	123	7e-32	123
sp:HIS3_BRASB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.45	111	51	1	19	125	6	116	7e-32	120
rs:WP_015171685	phosphoribosyl-AMP cyclohydrolase [Geitlerinema sp. PCC 7407].	55.56	99	43	1	18	115	11	109	7e-32	123
rs:WP_044107402	imidazole glycerol phosphate synthase [cyanobacterium endosymbiont of Epithemia turgida].	52.88	104	48	1	13	115	8	111	7e-32	123
rs:WP_025223654	phosphoribosyl-AMP cyclohydrolase [Methylophilaceae bacterium 11].	50.00	102	50	1	18	118	7	108	7e-32	120
rs:WP_027370613	phosphoribosyl-AMP cyclohydrolase [Desulfovermiculus halophilus].	55.14	107	46	2	24	128	11	117	7e-32	120
rs:WP_035719721	phosphoribosyl-AMP cyclohydrolase [Gordonia shandongensis].	56.57	99	43	0	16	114	9	107	7e-32	120
rs:WP_045086205	phosphoribosyl-AMP cyclohydrolase [Candidatus Evansia muelleri].	45.00	120	65	1	13	131	17	136	7e-32	121
rs:WP_034968827	phosphoribosyl-ATP diphosphatase [Campylobacter mucosalis].	49.04	104	53	0	23	126	10	113	7e-32	124
rs:WP_008880304	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Geobacillus].	56.84	95	41	0	18	112	5	99	7e-32	123
rs:WP_041841993	phosphoribosyl-AMP cyclohydrolase [Actinoplanes friuliensis].	54.29	105	47	1	9	112	15	119	7e-32	120
rs:WP_004561853	phosphoribosyl-AMP cyclohydrolase [Amycolatopsis vancoresmycina].	53.15	111	47	1	15	125	8	113	7e-32	120
rs:WP_019999551	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Desulfovibrio].	60.87	92	35	1	23	113	12	103	7e-32	120
tr:A0A024H457_9MICC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	56.70	97	42	0	16	112	42	138	7e-32	121
rs:WP_013224158	phosphoribosyl-AMP cyclohydrolase [Amycolatopsis mediterranei].	53.15	111	47	1	15	125	8	113	7e-32	120
rs:WP_034140617	phosphoribosyl-ATP pyrophosphatase [Desulfosporosinus sp. BICA1-9].	50.00	108	53	1	13	119	9	116	7e-32	123
rs:WP_019630685	phosphoribosyl-AMP cyclohydrolase [Actinomadura atramentaria].	56.44	101	44	0	18	118	19	119	7e-32	120
sp:HIS3_CHRVO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	51.92	104	49	1	18	120	12	115	7e-32	120
rs:WP_018770780	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. 162MFSha1.1].	56.70	97	42	0	16	112	41	137	7e-32	121
tr:A0A078KEI5_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	45.00	120	65	1	13	131	13	132	7e-32	120
rs:WP_024582421	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium].	51.40	107	52	0	19	125	19	125	8e-32	121
tr:D4K2D6_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	55.56	99	44	0	18	116	3	101	8e-32	123
rs:WP_012190284	phosphoribosyl-ATP pyrophosphatase [Herpetosiphon aurantiacus].	52.38	105	49	1	18	122	4	107	8e-32	123
rs:WP_013826250	phosphoribosyl-AMP cyclohydrolase [Methanobacterium paludis].	50.00	116	54	1	2	113	28	143	8e-32	122
rs:WP_022287378	phosphoribosyl-AMP cyclohydrolase [Ruminococcus sp. CAG:57].	52.43	103	49	0	20	122	15	117	8e-32	120
rs:WP_028150232	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium japonicum].	51.35	111	51	1	19	126	17	127	8e-32	121
tr:M5A288_9ACTN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	59.79	97	38	1	18	113	20	116	8e-32	120
rs:WP_036604946	phosphoribosyl-ATP pyrophosphatase [Paenibacillus assamensis].	56.25	96	42	0	17	112	10	105	8e-32	124
tr:C4LI94_CORK4	RecName: Full=Imidazole glycerol phosphate synthase subunit hisF {ECO:0000256|RuleBase:RU003659}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216}; EC=4.1.3.- {ECO:0000256|RuleBase:RU003659, ECO:0000256|SAAS:SAAS00088643};	60.00	95	38	0	18	112	274	368	8e-32	130
rs:WP_026540360	phosphoribosyl-AMP cyclohydrolase [Arthrobacter nicotinovorans].	55.67	97	43	0	16	112	29	125	8e-32	120
rs:WP_008133721	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. YR681].	55.56	99	44	0	19	117	17	115	8e-32	121
rs:WP_037299057	phosphoribosyl-AMP cyclohydrolase [Ruminococcus flavefaciens].	53.33	105	48	1	19	122	11	115	8e-32	120
rs:WP_036650324	phosphoribosyl-ATP pyrophosphatase [Paenibacillus pini].	54.17	96	44	0	18	113	18	113	8e-32	123
sp:HIS3_METMA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	55.45	101	44	1	13	113	2	101	8e-32	120
rs:WP_035196150	phosphoribosyl-AMP cyclohydrolase, partial [Akkermansia muciniphila].	54.81	104	46	1	19	121	20	123	8e-32	120
rs:WP_011888176	phosphoribosyl-ATP pyrophosphatase [Geobacillus thermodenitrificans].	56.84	95	41	0	18	112	5	99	8e-32	123
rs:WP_041536019	phosphoribosyl-AMP cyclohydrolase [Parvibaculum lavamentivorans].	54.21	107	47	1	15	119	21	127	8e-32	121
rs:WP_014052257	phosphoribosyl-AMP cyclohydrolase [halophilic archaeon DL31].	51.92	104	50	0	18	121	15	118	8e-32	121
rs:WP_019286092	hypothetical protein, partial [Rhodococcus sp. R04].	60.00	90	36	0	25	114	1	90	8e-32	119
rs:WP_013820766	phosphoribosyl-AMP cyclohydrolase [Methylomonas methanica].	45.69	116	62	1	16	130	7	122	8e-32	120
rs:WP_034660080	phosphoribosyl-ATP pyrophosphatase [Bacillus pumilus].	57.89	95	40	0	18	112	7	101	8e-32	123
rs:WP_022268637	phosphoribosyl-AMP cyclohydrolase [Firmicutes bacterium CAG:424].	56.38	94	41	0	20	113	8	101	8e-32	120
rs:WP_021939149	phosphoribosyl-ATP diphosphatase [Coprococcus sp. CAG:782].	52.83	106	48	1	9	114	214	317	8e-32	127
rs:WP_013863816	phosphoribosyl-AMP cyclohydrolase [Microlunatus phosphovorus].	58.95	95	39	0	18	112	23	117	8e-32	120
rs:WP_046436879	phosphoribosyl-AMP cyclohydrolase [Ruminococcus sp. UNK.MGS-30].	56.84	95	41	0	20	114	13	107	8e-32	120
rs:WP_022383218	phosphoribosyl-ATP diphosphatase [Dialister sp. CAG:357].	45.45	121	63	1	12	129	3	123	8e-32	123
rs:WP_036052207	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. URHD0069].	52.48	101	48	0	19	119	21	121	8e-32	121
rs:WP_025930001	imidazole glycerol phosphate synthase [Prochlorococcus sp. scB241_528O2].	50.46	109	53	1	10	117	4	112	8e-32	123
rs:WP_022171776	phosphoribosyl-ATP diphosphatase [Blautia sp. CAG:52].	49.56	113	57	0	1	113	3	115	8e-32	120
rs:WP_022086631	imidazole glycerol phosphate synthase subunit HisF [Roseburia sp. CAG:197].	54.81	104	47	0	10	113	220	323	8e-32	127
rs:WP_007793811	phosphoribosyl-AMP cyclohydrolase [Rhizobium sp. CF122].	51.28	117	55	1	17	131	22	138	8e-32	121
rs:WP_042436468	phosphoribosyl-AMP cyclohydrolase [Clostridium sp. JCD].	57.00	100	42	1	20	118	17	116	8e-32	120
rs:WP_034595142	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. NIPH 298].	50.00	114	55	1	2	113	10	123	8e-32	120
rs:WP_005945674	imidazole glycerol phosphate synthase [Blautia hydrogenotrophica CAG:147].	56.12	98	43	0	16	113	227	324	8e-32	127
rs:WP_038116630	phosphoribosyl-AMP cyclohydrolase [Veillonella sp. AS16].	52.83	106	44	1	12	117	4	103	8e-32	119
rs:WP_018761153	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. 135MFCol5.1].	56.70	97	42	0	16	112	41	137	8e-32	121
rs:WP_008512867	phosphoribosyl-AMP cyclohydrolase [Methanobacterium sp. Maddingley MBC34].	50.48	105	52	0	21	125	13	117	8e-32	120
rs:WP_036535687	phosphoribosyl-AMP cyclohydrolase [Nocardia cyriacigeorgica].	56.84	95	41	0	18	112	11	105	8e-32	120
rs:WP_009489446	phosphoribosyl-AMP cyclohydrolase [Microvirga lotononidis].	49.60	125	56	3	8	125	13	137	8e-32	120
rs:WP_033512265	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium mongoliense].	54.21	107	48	1	7	112	5	111	8e-32	120
tr:A0A0C7DVE9_9GAMM	SubName: Full=HisI protein {ECO:0000313|EMBL:CEL12316.1}; EC=3.5.4.19 {ECO:0000313|EMBL:CEL12316.1};	50.93	108	53	0	17	124	8	115	8e-32	120
rs:WP_019678613	phosphoribosyl-AMP cyclohydrolase [Ruminococcus flavefaciens].	53.33	105	48	1	19	122	11	115	8e-32	120
tr:N9LIJ7_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	50.00	114	55	1	2	113	12	125	9e-32	120
tr:L8LX01_9CYAN	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	55.56	99	43	1	18	115	34	132	9e-32	123
gpu:AP014685_206	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium diazoefficiens]	50.46	109	52	1	19	125	17	125	9e-32	120
rs:WP_046129498	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. TH008].	54.81	104	46	1	18	121	7	109	9e-32	122
tr:C2GKQ9_9CORY	RecName: Full=Imidazole glycerol phosphate synthase subunit hisF {ECO:0000256|RuleBase:RU003659}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216}; EC=4.1.3.- {ECO:0000256|RuleBase:RU003659, ECO:0000256|SAAS:SAAS00088643};	56.12	98	42	1	15	112	261	357	9e-32	126
rs:WP_033514680	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium pullorum].	56.84	95	41	0	18	112	21	115	9e-32	120
rs:WP_004959480	phosphoribosyl-AMP cyclohydrolase [Haloarcula sinaiiensis].	55.00	100	45	0	18	117	6	105	9e-32	120
rs:WP_043595369	phosphoribosyl-AMP cyclohydrolase [Chromobacterium violaceum].	51.92	104	49	1	18	120	14	117	9e-32	120
rs:WP_027576795	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. WSM1743].	53.54	99	46	0	19	117	17	115	9e-32	120
sp:HIS3_BRADU	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.46	109	52	1	19	125	17	125	9e-32	120
tr:F5XYB8_RAMTT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	53.77	106	45	1	29	130	2	107	9e-32	120
rs:WP_015768671	phosphoribosyl-AMP cyclohydrolase [Candidatus Accumulibacter phosphatis].	54.90	102	46	0	18	119	23	124	9e-32	120
rs:WP_015761833	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Halomicrobium].	53.00	100	47	0	18	117	6	105	9e-32	120
rs:WP_008847992	phosphoribosyl-AMP cyclohydrolase [Halorubrum kocurii].	53.00	100	47	0	18	117	13	112	9e-32	120
rs:WP_035775042	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. H5].	57.89	95	40	0	18	112	27	121	9e-32	120
rs:WP_043343065	phosphoribosyl-AMP cyclohydrolase, partial [Methylobacterium sp. EUR3 AL-11].	53.85	104	46	1	15	116	25	128	9e-32	120
rs:WP_004031108	phosphoribosyl-AMP cyclohydrolase [Methanobacterium formicicum].	51.43	105	51	0	21	125	13	117	9e-32	120
rs:WP_013914008	phosphoribosyl-ATP pyrophosphatase [Paenibacillus mucilaginosus].	54.90	102	46	0	16	117	16	117	9e-32	123
tr:A7HWI8_PARL1	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.21	107	47	1	15	119	26	132	9e-32	121
rs:WP_008674293	phosphoribosyl-AMP cyclohydrolase [Rhodopirellula sallentina].	50.00	124	57	2	1	121	1	122	9e-32	120
rs:WP_015226137	phosphoribosyl-AMP cyclohydrolase [Halothece sp. PCC 7418].	55.34	103	43	2	20	121	15	115	9e-32	122
rs:WP_043480638	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. SPG23].	56.70	97	42	0	16	112	19	115	9e-32	120
rs:WP_003397310	phosphoribosyl-AMP cyclohydrolase [Anoxybacillus flavithermus].	54.46	101	46	0	18	118	6	106	9e-32	122
tr:X1S7K3_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_S07076 {ECO:0000313|EMBL:GAI88913.1};	51.85	108	51	1	24	130	11	118	9e-32	120
rs:WP_034915325	phosphoribosyl-AMP cyclohydrolase [Candidatus Accumulibacter sp. BA-91].	55.67	97	42	1	18	113	14	110	9e-32	120
rs:WP_045875442	phosphoribosyl-AMP cyclohydrolase [Frankia sp. DC12].	56.84	95	41	0	18	112	16	110	9e-32	120
rs:WP_039156820	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium japonicum].	50.45	111	52	1	19	126	17	127	9e-32	120
rs:WP_035701761	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. CCBAU 43298].	54.55	99	45	0	19	117	17	115	9e-32	120
rs:WP_045895166	phosphoribosyl-AMP cyclohydrolase [Clostridium botulinum].	57.61	92	39	0	23	114	16	107	9e-32	120
rs:WP_027720033	phosphoribosyl-AMP cyclohydrolase [Desulfurobacterium sp. TC5-1].	55.56	99	44	0	24	122	18	116	9e-32	120
rs:WP_029074857	phosphoribosyl-AMP cyclohydrolase [Kaistia adipata].	50.43	117	53	2	19	130	22	138	9e-32	121
rs:WP_036581871	phosphoribosyl-ATP pyrophosphatase [Paenibacillus darwinianus].	53.00	100	47	0	18	117	12	111	9e-32	123
rs:WP_027095767	phosphoribosyl-ATP pyrophosphatase [[Clostridium] viride].	50.47	107	53	0	13	119	2	108	9e-32	122
rs:WP_019617518	hypothetical protein [Pseudoclavibacter faecalis].	50.44	113	54	1	2	112	1	113	1e-31	120
rs:WP_013426082	phosphoribosyl-AMP cyclohydrolase [Frankia sp. EuI1c].	56.84	95	41	0	18	112	16	110	1e-31	120
rs:WP_025643442	phosphoribosyl-ATP diphosphatase [[Clostridium] scindens].	56.19	105	44	1	9	113	223	325	1e-31	126
rs:WP_043449708	phosphoribosyl-AMP cyclohydrolase [Arthrobacter phenanthrenivorans].	56.70	97	42	0	16	112	22	118	1e-31	120
rs:WP_043523785	phosphoribosyl-AMP cyclohydrolase [Actinoplanes utahensis].	56.84	95	41	0	18	112	18	112	1e-31	120
rs:WP_008339516	phosphoribosyl-ATP diphosphatase [Alicyclobacillus acidocaldarius].	50.43	117	56	2	12	126	7	123	1e-31	124
rs:WP_020046002	hypothetical protein [actinobacterium SCGC AAA027-M14].	58.89	90	37	0	24	113	18	107	1e-31	120
rs:WP_040462772	phosphoribosyl-AMP cyclohydrolase [[Eubacterium] dolichum].	54.55	99	44	1	24	121	11	109	1e-31	119
rs:WP_036387322	hypothetical protein [Moraxella caprae].	57.14	98	41	1	17	113	7	104	1e-31	124
rs:WP_013137521	phosphoribosyl-AMP cyclohydrolase [Segniliparus rotundus].	50.43	115	54	1	1	112	1	115	1e-31	120
rs:WP_004797454	phosphoribosyl-AMP cyclohydrolase [Eubacterium dolichum CAG:375].	54.55	99	44	1	24	121	10	108	1e-31	119
rs:WP_040939087	imidazole glycerol phosphate synthase [Prochloron didemni].	49.14	116	58	1	1	115	1	116	1e-31	122
rs:WP_035857035	phosphoribosyl-AMP cyclohydrolase [Cryptosporangium arvum].	56.84	95	41	0	18	112	12	106	1e-31	120
rs:WP_025657490	hypothetical protein [Clostridiales bacterium VE202-21].	55.24	105	45	1	9	113	222	324	1e-31	126
rs:WP_016540132	phosphoribosyl-AMP cyclohydrolase [Acinetobacter gyllenbergii].	50.88	114	54	1	2	113	10	123	1e-31	120
rs:WP_034715880	phosphoribosyl-AMP cyclohydrolase [Intrasporangium chromatireducens].	58.95	95	39	0	18	112	15	109	1e-31	120
rs:WP_028712754	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Paracoccus].	53.15	111	48	2	19	125	22	132	1e-31	121
gpu:CP011832_2957	Phosphoribosyl-ATP pyrophosphatase [Geobacillus sp. 12AMOR1]	52.78	108	50	1	15	122	2	108	1e-31	122
tr:A0A0A6NYC2_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	46.49	114	60	1	18	130	8	121	1e-31	120
rs:WP_046253771	phosphoribosyl-AMP cyclohydrolase [Mycobacterium chelonae].	58.76	97	40	0	16	112	10	106	1e-31	120
rs:WP_007046067	phosphoribosyl-ATP pyrophosphatase [Subdoligranulum variabile].	51.46	103	50	0	14	116	6	108	1e-31	122
rs:WP_010111775	phosphoribosyl-ATP diphosphatase [Acinetobacter sp. P8-3-8].	53.77	106	47	2	18	121	10	115	1e-31	124
rs:WP_044424723	phosphoribosyl-ATP diphosphatase [Acinetobacter pittii].	56.70	97	41	1	18	113	10	106	1e-31	124
rs:WP_002808352	phosphoribosyl-ATP pyrophosphatase [Prochlorococcus marinus].	50.46	109	53	1	10	117	4	112	1e-31	122
rs:WP_028277042	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. I3].	60.00	95	38	0	18	112	45	139	1e-31	121
rs:WP_045050097	phosphoribosyl-AMP cyclohydrolase [Chromobacterium violaceum].	49.12	114	57	1	18	130	14	127	1e-31	120
rs:WP_028953986	phosphoribosyl-ATP pyrophosphatase [Succinispira mobilis].	51.92	104	50	0	11	114	1	104	1e-31	122
rs:WP_040566810	phosphoribosyl-AMP cyclohydrolase [Methylosinus trichosporium].	51.89	106	49	1	19	122	15	120	1e-31	120
rs:WP_019426359	phosphoribosyl-AMP cyclohydrolase [Limnohabitans sp. Rim28].	48.65	111	52	2	18	123	7	117	1e-31	120
rs:WP_041798680	phosphoribosyl-AMP cyclohydrolase [Rhodopseudomonas palustris].	49.56	113	56	1	19	130	10	122	1e-31	120
rs:WP_034269306	phosphoribosyl-AMP cyclohydrolase [Actinospica robiniae].	54.74	95	43	0	18	112	19	113	1e-31	120
rs:WP_005233554	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Acinetobacter].	54.72	106	46	2	18	121	10	115	1e-31	124
rs:WP_046297085	phosphoribosyl-AMP cyclohydrolase [Verrucomicrobia bacterium IMCC26134].	52.43	103	46	1	19	118	21	123	1e-31	120
rs:WP_027644021	phosphoribosyl-ATP diphosphatase [[Clostridium] clostridioforme].	56.44	101	44	0	18	118	239	339	1e-31	126
rs:WP_015083067	phosphoribosyl-AMP cyclohydrolase [Anabaena sp. 90].	54.55	99	44	1	18	115	18	116	1e-31	122
rs:WP_034600582	phosphoribosyl-ATP pyrophosphatase [Desulfosporosinus sp. HMP52].	50.93	108	52	1	13	119	9	116	1e-31	123
rs:WP_008000437	phosphoribosyl-AMP cyclohydrolase [Halorubrum aidingense].	51.92	104	50	0	14	117	21	124	1e-31	120
rs:WP_036202427	imidazole glycerol phosphate synthase [Megasphaera elsdenii].	52.08	96	46	0	18	113	9	104	1e-31	123
tr:A9KNX2_CLOPH	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	56.12	98	43	0	16	113	235	332	1e-31	126
rs:WP_038041779	imidazole glycerol phosphate synthase [Thermus yunnanensis].	50.47	107	53	0	13	119	1	107	1e-31	122
rs:WP_040932749	imidazole glycerol phosphate synthase, partial [Prochloron didemni].	50.00	114	56	1	1	113	1	114	1e-31	122
rs:WP_022367340	phosphoribosyl-ATP pyrophosphohydrolase [Firmicutes bacterium CAG:882].	60.20	98	39	0	16	113	198	295	1e-31	126
rs:WP_026167751	phosphoribosyl-AMP cyclohydrolase [Corynebacterium propinquum].	56.84	95	41	0	18	112	9	103	1e-31	119
tr:A0A0C7CNY1_9GAMM	SubName: Full=HisI protein {ECO:0000313|EMBL:CEI58609.1}; EC=3.5.4.19 {ECO:0000313|EMBL:CEI58609.1};	50.93	108	53	0	17	124	8	115	1e-31	120
rs:WP_038669562	phosphoribosyl-ATP pyrophosphatase [Pelosinus sp. UFO1].	54.46	101	46	0	18	118	7	107	1e-31	122
rs:WP_037309602	phosphoribosyl-AMP cyclohydrolase [Amycolatopsis orientalis].	57.73	97	41	0	18	114	11	107	1e-31	120
rs:WP_020630317	phosphoribosyl-AMP cyclohydrolase [Amycolatopsis alba].	57.73	97	41	0	18	114	11	107	1e-31	120
rs:WP_008709430	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Synergistaceae].	54.37	103	47	0	11	113	2	104	1e-31	122
rs:WP_026292785	phosphoribosyl-AMP cyclohydrolase [Rubritalea marina].	50.00	112	53	2	19	127	21	132	1e-31	120
sp:HIS3_METKA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.99	117	50	3	15	126	15	131	1e-31	120
rs:WP_044850021	phosphoribosyl-AMP cyclohydrolase [Amycolatopsis orientalis].	57.73	97	41	0	18	114	11	107	1e-31	120
rs:WP_034663495	phosphoribosyl-AMP cyclohydrolase, partial [Cellulomonas sp. KRMCY2].	57.89	95	40	0	18	112	19	113	1e-31	120
rs:WP_045851554	phosphoribosyl-ATP pyrophosphatase [Domibacillus enclensis].	54.74	95	43	0	18	112	5	99	1e-31	122
rs:WP_020561660	phosphoribosyl-AMP cyclohydrolase [Methylosarcina fibrata].	44.74	114	62	1	18	130	9	122	1e-31	120
rs:WP_013657480	phosphoribosyl-ATP pyrophosphatase [Cellulosilyticum lentocellum].	53.61	97	44	1	18	113	10	106	1e-31	122
rs:WP_036949185	phosphoribosyl-ATP diphosphatase [Pseudobutyrivibrio ruminis].	51.28	117	55	1	16	130	226	342	1e-31	126
rs:WP_021618414	phosphoribosyl-AMP cyclohydrolase [Alloscardovia omnicolens].	55.67	97	43	0	18	114	12	108	1e-31	120
rs:WP_024793076	phosphoribosyl-AMP cyclohydrolase [Tomitella biformata].	58.95	95	39	0	18	112	9	103	1e-31	119
rs:WP_029896731	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio sp. L21-Syr-AB].	53.27	107	49	1	23	128	9	115	1e-31	120
rs:WP_045273088	phosphoribosyl-AMP cyclohydrolase [Microbacterium azadirachtae].	56.84	95	41	0	18	112	13	107	1e-31	120
sp:HIS3_RHOP2	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	49.56	113	56	1	19	130	23	135	1e-31	120
rs:WP_019849882	phosphoribosyl-ATP pyrophosphatase [Desulfitobacterium sp. PCE1].	51.85	108	51	1	18	125	17	123	1e-31	122
rs:WP_034830098	phosphoribosyl-AMP cyclohydrolase [Clostridium pasteurianum].	54.26	94	43	0	24	117	15	108	1e-31	119
rs:WP_027315468	phosphoribosyl-AMP cyclohydrolase [Microvirga flocculans].	54.05	111	49	1	19	127	27	137	1e-31	120
rs:WP_044204503	imidazole glycerol phosphate synthase [Coleofasciculus chthonoplastes].	55.56	99	43	1	18	115	18	116	1e-31	122
rs:WP_025331286	phosphoribosyl-AMP cyclohydrolase [Snodgrassella alvi].	49.18	122	59	2	13	131	2	123	1e-31	120
rs:WP_040943153	imidazole glycerol phosphate synthase [Prochloron didemni].	50.00	114	56	1	1	113	1	114	1e-31	122
rs:WP_005935189	phosphoribosyl-AMP cyclohydrolase [Gordonia hirsuta].	60.82	97	38	0	18	114	11	107	1e-31	120
rs:WP_005537018	phosphoribosyl-AMP cyclohydrolase [Haloarcula argentinensis].	55.00	100	45	0	18	117	6	105	1e-31	120
rs:WP_009341784	phosphoribosyl-ATP pyrophosphatase [Raphidiopsis brookii].	49.14	116	58	1	1	115	1	116	1e-31	122
rs:WP_009393005	phosphoribosyl-ATP diphosphatase [Acinetobacter sp. WC-141].	56.70	97	41	1	18	113	10	106	1e-31	123
rs:WP_039201868	imidazole glycerol phosphate synthase [Aphanizomenon flos-aquae].	54.55	99	44	1	18	115	18	116	1e-31	122
rs:WP_002282161	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	53.68	95	44	0	22	116	11	105	1e-31	119
rs:WP_034869720	hypothetical protein [Clostridium lundense].	44.25	113	60	2	18	129	10	120	1e-31	122
rs:WP_018027117	hypothetical protein [Oligella urethralis].	52.38	105	49	1	18	121	7	111	1e-31	120
rs:WP_012956048	phosphoribosyl-AMP cyclohydrolase [Methanobrevibacter ruminantium].	48.72	117	58	1	17	131	4	120	1e-31	120
rs:WP_017393998	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Acinetobacter calcoaceticus/baumannii complex].	56.70	97	41	1	18	113	10	106	1e-31	123
rs:WP_022954925	phosphoribosyl-AMP cyclohydrolase [Perlucidibaca piscinae].	50.00	114	56	1	16	128	9	122	1e-31	120
rs:WP_037392722	phosphoribosyl-AMP cyclohydrolase [Snodgrassella alvi].	49.18	122	59	2	13	131	2	123	1e-31	120
rs:WP_029058752	phosphoribosyl-AMP cyclohydrolase [Stappia stellulata].	50.00	124	54	3	8	123	10	133	1e-31	120
rs:WP_004710809	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Acinetobacter calcoaceticus/baumannii complex].	56.70	97	41	1	18	113	10	106	1e-31	123
rs:WP_022256856	phosphoribosyl-AMP cyclohydrolase [Faecalibacterium sp. CAG:82].	55.56	99	44	0	18	116	3	101	1e-31	122
rs:WP_022313520	hypothetical protein [Clostridium sp. CAG:91].	59.38	96	39	0	18	113	229	324	1e-31	126
rs:WP_028894133	phosphoribosyl-AMP cyclohydrolase [Syntrophorhabdus aromaticivorans].	46.90	113	60	0	18	130	5	117	1e-31	120
rs:WP_003046075	phosphoribosyl-ATP pyrophosphatase [Thermus aquaticus].	50.50	101	50	0	13	113	1	101	1e-31	122
rs:WP_024848702	phosphoribosyl-AMP cyclohydrolase [Aminobacter sp. J41].	52.68	112	49	2	19	126	22	133	1e-31	120
rs:WP_035155769	phosphoribosyl-ATP pyrophosphatase [Cohnella thermotolerans].	54.63	108	45	1	6	113	2	105	1e-31	122
rs:WP_046234117	phosphoribosyl-ATP pyrophosphatase [Paenibacillus algorifonticola].	54.00	100	46	0	18	117	8	107	1e-31	123
rs:WP_013017760	phosphoribosyl-AMP cyclohydrolase [Stackebrandtia nassauensis].	51.85	108	49	1	8	112	2	109	1e-31	119
rs:WP_044101778	phosphoribosyl-ATP diphosphatase [Acinetobacter pittii].	56.70	97	41	1	18	113	10	106	1e-31	123
rs:WP_026735791	imidazole glycerol phosphate synthase [Fischerella sp. PCC 9605].	54.55	99	44	1	18	115	18	116	1e-31	122
rs:WP_019551082	phosphoribosyl-ATP pyrophosphatase [Thermus scotoductus].	49.53	107	54	0	13	119	1	107	1e-31	122
sp:HIS3_RHOPB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.93	108	52	1	19	125	23	130	1e-31	120
rs:WP_012855982	phosphoribosyl-ATP pyrophosphatase [Sulfurospirillum deleyianum].	55.10	98	44	0	17	114	8	105	1e-31	122
rs:WP_040350369	phosphoribosyl-ATP diphosphatase [Blautia hydrogenotrophica].	56.12	98	43	0	16	113	216	313	1e-31	126
rs:WP_025371198	phosphoribosyl-AMP cyclohydrolase [Advenella mimigardefordensis].	49.15	118	55	2	18	130	7	124	1e-31	120
rs:WP_014764154	phosphoribosyl-AMP cyclohydrolase [Sinorhizobium fredii].	53.10	113	49	2	17	125	22	134	1e-31	120
rs:WP_004009543	phosphoribosyl-AMP cyclohydrolase [Mobiluncus curtisii].	52.63	114	54	0	18	131	12	125	1e-31	120
rs:WP_004640866	phosphoribosyl-AMP cyclohydrolase [Acinetobacter calcoaceticus].	55.67	97	42	1	18	113	10	106	1e-31	123
rs:WP_022201140	hypothetical protein [Clostridium clostridioforme CAG:132].	56.44	101	44	0	18	118	239	339	1e-31	126
rs:WP_047196502	phosphoribosyl-AMP cyclohydrolase [[Polyangium] brachysporum].	47.01	117	58	1	18	130	7	123	1e-31	120
rs:WP_005037164	phosphoribosyl-AMP cyclohydrolase [Acinetobacter calcoaceticus].	55.67	97	42	1	18	113	10	106	1e-31	123
rs:WP_030201973	phosphoribosyl-AMP cyclohydrolase [Corynebacterium variabile].	57.89	95	40	0	18	112	18	112	1e-31	120
rs:WP_028180051	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium].	50.46	109	52	1	19	125	17	125	1e-31	120
rs:WP_009509948	phosphoribosyl-AMP cyclohydrolase [Opitutaceae bacterium TAV5].	53.27	107	47	1	15	118	16	122	1e-31	120
rs:WP_035088595	phosphoribosyl-AMP cyclohydrolase [Caulobacter henricii].	55.14	107	46	1	14	118	19	125	1e-31	120
rs:WP_012321557	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Methylobacterium].	49.18	122	54	3	7	125	19	135	1e-31	120
tr:M2XFL3_9MICC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.73	97	41	0	16	112	23	119	2e-31	120
rs:WP_044743790	phosphoribosyl-ATP pyrophosphatase [Anoxybacillus sp. ATCC BAA-2555].	52.78	108	50	1	15	122	2	108	2e-31	122
rs:WP_033015053	phosphoribosyl-ATP pyrophosphatase [Geobacillus stearothermophilus].	51.85	108	51	1	15	122	2	108	2e-31	122
rs:WP_027321968	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. URHB0009].	52.00	100	48	0	13	112	1	100	2e-31	122
rs:WP_033021520	phosphoribosyl-ATP pyrophosphatase [Geobacillus sp. G1w1].	52.78	108	50	1	15	122	2	108	2e-31	122
rs:WP_046563883	phosphoribosyl-AMP cyclohydrolase [Micromonospora sp. HK10].	54.64	97	44	0	18	114	37	133	2e-31	120
rs:WP_015261749	phosphoribosyl-ATP pyrophosphatase [Desulfitobacterium dichloroeliminans].	54.17	96	44	0	18	113	17	112	2e-31	122
rs:WP_011321574	phosphoribosyl-ATP pyrophosphatase [Anabaena variabilis].	55.56	99	43	1	18	115	18	116	2e-31	122
rs:WP_019877614	hypothetical protein [Sporichthya polymorpha].	56.70	97	42	0	16	112	13	109	2e-31	120
rs:WP_015285073	phosphoribosyl-AMP cyclohydrolase [Methanoregula formicica].	56.70	97	41	1	17	113	3	98	2e-31	119
rs:WP_005196180	phosphoribosyl-AMP cyclohydrolase [Gordonia rubripertincta].	56.70	97	42	0	18	114	11	107	2e-31	119
rs:WP_033012064	phosphoribosyl-ATP pyrophosphatase [Geobacillus stearothermophilus].	52.78	108	50	1	15	122	2	108	2e-31	122
rs:WP_032049910	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.10	98	43	1	18	114	10	107	2e-31	123
rs:WP_033414663	phosphoribosyl-AMP cyclohydrolase [Actinomycetospora chiangmaiensis].	58.95	95	39	0	18	112	9	103	2e-31	119
rs:WP_012230957	phosphoribosyl-AMP cyclohydrolase [Candidatus Microthrix parvicella].	58.33	96	40	0	18	113	6	101	2e-31	119
rs:WP_039930426	phosphoribosyl-ATP diphosphatase, partial [Anaerostipes sp. 3_2_56FAA].	53.77	106	47	1	9	114	164	267	2e-31	125
rs:WP_027549067	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. WSM2254].	51.35	111	51	1	19	126	17	127	2e-31	120
rs:WP_044741448	phosphoribosyl-ATP pyrophosphatase [Anoxybacillus sp. ATCC BAA-2555].	52.00	100	48	0	13	112	1	100	2e-31	122
rs:WP_033843083	phosphoribosyl-ATP pyrophosphatase [Geobacillus subterraneus].	52.78	108	50	1	15	122	2	108	2e-31	122
rs:WP_029643801	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Micrococcales].	57.73	97	41	0	16	112	22	118	2e-31	120
rs:WP_026206095	phosphoribosyl-AMP cyclohydrolase [Actinoplanes globisporus].	49.57	115	55	1	2	113	1	115	2e-31	120
rs:WP_024828687	phosphoribosyl-AMP cyclohydrolase [Methylobacterium sp. EUR3 AL-11].	50.88	114	53	2	15	125	22	135	2e-31	120
rs:WP_005301863	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. NIPH 542].	55.67	97	42	1	18	113	10	106	2e-31	123
rs:WP_007864439	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Clostridiales].	45.97	124	60	1	2	118	216	339	2e-31	126
rs:WP_020521251	hypothetical protein [Catelliglobosispora koreensis].	52.21	113	53	1	1	112	1	113	2e-31	119
rs:WP_019899785	phosphoribosyl-AMP cyclohydrolase [Methylotenera mobilis].	52.00	100	47	1	20	118	9	108	2e-31	119
rs:WP_020508490	phosphoribosyl-AMP cyclohydrolase [Lamprocystis purpurea].	50.43	117	56	2	16	130	7	123	2e-31	120
rs:WP_037240843	phosphoribosyl-AMP cyclohydrolase [Rhodomicrobium udaipurense].	53.66	123	50	3	7	128	21	137	2e-31	120
rs:WP_001066575	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	56.70	97	41	1	18	113	10	106	2e-31	123
rs:WP_032043741	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	2e-31	123
sp:HIS3_METHJ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	54.64	97	44	0	17	113	12	108	2e-31	120
rs:WP_045924367	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium asteroides].	56.84	95	41	0	18	112	20	114	2e-31	120
rs:WP_002715324	phosphoribosyl-AMP cyclohydrolase [Afipia felis].	50.00	110	52	2	19	125	20	129	2e-31	120
rs:WP_046436606	phosphoribosyl-AMP cyclohydrolase [Akkermansia sp. UNK.MGS-1].	54.81	104	46	1	19	121	29	132	2e-31	120
rs:WP_045792583	phosphoribosyl-ATP diphosphatase [Acinetobacter brisouii].	53.77	106	47	2	18	121	10	115	2e-31	123
tr:U2EVR3_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	57.14	98	42	0	16	113	226	323	2e-31	125
rs:WP_046700523	phosphoribosyl-AMP cyclohydrolase [Moraxella bovoculi].	58.16	98	40	1	17	113	6	103	2e-31	123
rs:WP_005465776	phosphoribosyl-AMP cyclohydrolase [Saccharomonospora glauca].	53.70	108	45	1	18	125	12	114	2e-31	119
rs:WP_022497370	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Megasphaera].	52.08	96	46	0	18	113	9	104	2e-31	122
rs:WP_037041374	phosphoribosyl-AMP cyclohydrolase [Pseudonocardia autotrophica].	58.95	95	39	0	18	112	16	110	2e-31	119
rs:WP_045448155	phosphoribosyl-AMP cyclohydrolase [alpha proteobacterium MA2].	49.57	117	55	2	19	131	27	143	2e-31	120
rs:WP_004754483	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. ANC 3789].	53.77	106	47	2	18	121	10	115	2e-31	123
rs:WP_045302465	phosphoribosyl-AMP cyclohydrolase [Microbacterium trichothecenolyticum].	53.92	102	47	0	11	112	5	106	2e-31	119
rs:WP_034623808	phosphoribosyl-ATP pyrophosphatase, partial [Bacillus safensis].	58.24	91	38	0	18	108	7	97	2e-31	119
rs:WP_028647794	phosphoribosyl-AMP cyclohydrolase [Nocardiopsis sp. CNT312].	57.89	95	40	0	18	112	14	108	2e-31	119
rs:WP_008173257	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. B14905].	50.00	104	52	0	18	121	5	108	2e-31	122
rs:WP_012513906	phosphoribosyl-ATP pyrophosphatase [Hydrogenobaculum sp. Y04AAS1].	52.58	97	45	1	18	113	6	102	2e-31	122
rs:WP_014286380	phosphoribosyl-AMP cyclohydrolase [Pseudovibrio sp. FO-BEG1].	55.00	100	43	1	19	116	28	127	2e-31	120
rs:WP_036059936	phosphoribosyl-AMP cyclohydrolase [Listeria weihenstephanensis].	52.83	106	49	1	17	122	2	106	2e-31	119
rs:WP_038057677	imidazole glycerol phosphate synthase [Thermus sp. YIM 77409].	49.53	107	54	0	13	119	1	107	2e-31	122
rs:WP_046228474	phosphoribosyl-ATP pyrophosphatase [Paenibacillus dauci].	53.92	102	47	0	15	116	12	113	2e-31	122
rs:WP_015524924	phosphoribosyl-ATP pyrophosphohydrolase [Ruminococcus sp. CAG:90].	57.14	98	42	0	16	113	226	323	2e-31	125
rs:WP_008547829	phosphoribosyl-AMP cyclohydrolase [Pseudovibrio sp. JE062].	55.00	100	43	1	19	116	28	127	2e-31	120
rs:WP_013556523	phosphoribosyl-ATP pyrophosphatase [Deinococcus maricopensis].	50.46	109	54	0	18	126	15	123	2e-31	122
rs:WP_002047642	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	2e-31	123
rs:WP_006040844	phosphoribosyl-ATP pyrophosphatase [Synechococcus sp. WH 7805].	56.60	106	42	2	18	122	12	114	2e-31	122
rs:WP_022715674	phosphoribosyl-AMP cyclohydrolase [Rhizobium mongolense].	50.43	117	56	1	17	131	23	139	2e-31	120
sp:HIS3_CLOB6	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	57.14	91	39	0	24	114	17	107	2e-31	119
rs:WP_002574568	phosphoribosyl-ATP diphosphatase [[Clostridium] bolteae].	58.95	95	39	0	24	118	245	339	2e-31	125
rs:WP_028349131	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium elkanii].	50.98	102	50	0	19	120	19	120	2e-31	120
rs:WP_026461148	phosphoribosyl-AMP cyclohydrolase [Actinomyces suimastitidis].	58.95	95	39	0	18	112	11	105	2e-31	119
rs:WP_004606022	imidazole glycerol phosphate synthase [[Clostridium] scindens].	56.19	105	44	1	9	113	223	325	2e-31	125
sp:HIS3_METAC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	54.46	101	45	1	13	113	2	101	2e-31	119
rs:WP_046812049	phosphoribosyl-ATP diphosphatase [Acinetobacter pittii].	55.67	97	42	1	18	113	10	106	2e-31	123
rs:WP_032370329	phosphoribosyl-AMP cyclohydrolase [Rhodococcus fascians].	54.08	98	45	0	15	112	8	105	2e-31	119
tr:G0VL69_MEGEL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	52.08	96	46	0	18	113	4	99	2e-31	122
rs:WP_003353541	phosphoribosyl-ATP pyrophosphatase [Bacillus smithii].	53.47	101	47	0	12	112	3	103	2e-31	122
rs:WP_003491225	phosphoribosyl-AMP cyclohydrolase [Clostridium sporogenes].	56.99	93	40	0	22	114	15	107	2e-31	119
tr:A0A077M8A2_9MICO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.73	97	41	0	16	112	10	106	2e-31	119
rs:WP_012899325	phosphoribosyl-AMP cyclohydrolase [Methanocella paludicola].	59.78	92	37	0	22	113	10	101	2e-31	119
rs:WP_023364869	hypothetical protein [Spiribacter sp. UAH-SP71].	51.30	115	55	1	18	131	7	121	2e-31	119
rs:WP_045935322	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium asteroides].	56.84	95	41	0	18	112	20	114	2e-31	120
rs:WP_008376664	phosphoribosyl-AMP cyclohydrolase [Gordonia malaquae].	57.58	99	42	0	16	114	9	107	2e-31	119
rs:WP_022197614	phosphoribosyl-AMP cyclohydrolase [Akkermansia muciniphila CAG:154].	54.81	104	46	1	19	121	29	132	2e-31	120
sp:HIS3_DESAG	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.73	110	51	1	23	131	16	125	2e-31	119
rs:WP_006554067	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Rhodococcus].	55.56	99	44	0	18	116	14	112	2e-31	119
rs:WP_029500914	phosphoribosyl-ATP pyrophosphatase [Kurthia huakuii].	51.79	112	53	1	18	128	3	114	2e-31	122
rs:WP_024627687	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium sp. A11].	56.84	95	41	0	18	112	20	114	2e-31	120
rs:WP_011747659	phosphoribosyl-AMP cyclohydrolase [Paracoccus denitrificans].	55.34	103	45	1	19	120	22	124	2e-31	120
rs:WP_017761024	phosphoribosyl-AMP cyclohydrolase [Pseudacidovorax intermedius].	50.00	106	49	1	18	119	8	113	2e-31	119
rs:WP_002583533	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Clostridiales].	56.44	101	44	0	18	118	239	339	2e-31	125
rs:WP_029100240	phosphoribosyl-ATP pyrophosphatase [Brevibacillus thermoruber].	52.88	104	49	0	18	121	10	113	2e-31	122
rs:WP_033497087	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium coryneforme].	57.89	95	40	0	18	112	20	114	2e-31	120
rs:WP_044948668	hypothetical protein [Lachnospiraceae bacterium V9D3004].	53.57	112	47	1	7	113	191	302	2e-31	125
rs:WP_016286464	phosphoribosyl-ATP diphosphatase [Lachnospiraceae bacterium 3-1].	56.19	105	44	1	9	113	221	323	2e-31	125
rs:WP_027159539	phosphoribosyl-AMP cyclohydrolase [Methylobacter luteus].	50.49	103	50	1	18	119	9	111	2e-31	119
rs:WP_018455377	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. WSM4349].	50.46	109	52	1	19	125	17	125	2e-31	120
rs:WP_004650007	phosphoribosyl-AMP cyclohydrolase [Acinetobacter bohemicus].	55.67	97	42	1	18	113	10	106	2e-31	123
rs:WP_022798473	phosphoribosyl-ATP pyrophosphatase [Thermus islandicus].	48.62	109	56	0	13	121	1	109	2e-31	122
rs:WP_045436851	phosphoribosyl-ATP diphosphatase [Acinetobacter calcoaceticus].	55.67	97	42	1	18	113	10	106	2e-31	123
rs:WP_039946684	phosphoribosyl-ATP diphosphatase, partial [Anaerostipes caccae].	53.77	106	47	1	9	114	164	267	2e-31	125
rs:WP_016935787	phosphoribosyl-AMP cyclohydrolase [Rhodococcus sp. R1101].	55.56	99	44	0	18	116	14	112	2e-31	119
rs:WP_022360502	histidine biosynthesis bifunctional protein HisIE [Clostridium sp. CAG:43].	48.25	114	59	0	8	121	10	123	2e-31	122
sp:HIS3_CORDI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	56.84	95	40	1	18	112	17	110	2e-31	119
rs:WP_024714161	phosphoribosyl-ATP pyrophosphatase [Bacillus tequilensis].	56.84	95	41	0	18	112	7	101	2e-31	122
rs:WP_028137198	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium japonicum].	52.53	99	47	0	19	117	17	115	2e-31	120
rs:WP_006590919	phosphoribosyl-AMP cyclohydrolase [Kineosphaera limosa].	52.73	110	51	1	6	114	2	111	2e-31	119
tr:B4VI79_9CYAN	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	55.56	99	43	1	18	115	37	135	2e-31	122
tr:W1JVW5_9BRAD	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:EJZ32863.1}; EC=3.5.4.19 {ECO:0000313|EMBL:EJZ32863.1}; Flags: Fragment;	52.00	100	48	0	19	118	6	105	2e-31	119
rs:WP_004516501	phosphoribosyl-AMP cyclohydrolase [Haloarcula vallismortis].	55.00	100	45	0	18	117	6	105	2e-31	119
rs:WP_036717961	phosphoribosyl-ATP pyrophosphatase [Paenibacillus harenae].	53.92	102	47	0	16	117	7	108	2e-31	122
tr:X0XTL9_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_S40758 {ECO:0000313|EMBL:GAG46605.1}; Flags: Fragment;	53.21	109	44	2	9	116	7	109	2e-31	119
rs:WP_045246437	imidazole glycerol phosphate synthase [Thermus filiformis].	51.89	106	49	1	11	116	1	104	2e-31	121
rs:WP_014901721	phosphoribosyl-ATP pyrophosphatase [Desulfosporosinus meridiei].	49.11	112	56	1	13	123	9	120	2e-31	122
rs:WP_002274824	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	53.68	95	44	0	22	116	11	105	2e-31	119
rs:WP_007318394	phosphoribosyl-AMP cyclohydrolase [Gordonia effusa].	57.58	99	42	0	16	114	11	109	2e-31	119
rs:WP_033381568	phosphoribosyl-AMP cyclohydrolase [Kibdelosporangium aridum].	57.89	95	40	0	18	112	11	105	2e-31	119
rs:WP_004006844	phosphoribosyl-AMP cyclohydrolase [Mobiluncus curtisii].	52.63	114	54	0	18	131	12	125	2e-31	119
rs:WP_021895137	hypothetical protein [Clostridium bolteae CAG:59].	55.45	101	45	0	18	118	239	339	2e-31	125
rs:WP_028236384	phosphoribosyl-ATP diphosphatase [Pseudobutyrivibrio sp. MD2005].	51.28	117	55	1	16	130	227	343	2e-31	125
rs:WP_008201700	phosphoribosyl-ATP pyrophosphatase [Microcystis sp. T1-4].	52.83	106	47	2	9	113	6	109	2e-31	122
rs:WP_037515134	phosphoribosyl-AMP cyclohydrolase [Sphingopyxis sp. LC81].	54.37	103	46	1	19	120	14	116	2e-31	119
rs:WP_044935014	phosphoribosyl-ATP diphosphatase [Pseudobutyrivibrio sp. LB2011].	49.57	117	57	1	16	130	211	327	2e-31	125
rs:WP_044930487	imidazole glycerol phosphate synthase [[Ruminococcus] gnavus].	56.99	93	40	0	21	113	2	94	2e-31	121
rs:WP_019833103	hypothetical protein [Sphingomonas sp. PR090111-T3T-6A].	50.86	116	53	2	12	123	4	119	2e-31	119
rs:WP_004688381	phosphoribosyl-AMP cyclohydrolase [Brucella neotomae].	51.75	114	53	1	19	130	23	136	2e-31	119
rs:WP_006359158	phosphoribosyl-AMP cyclohydrolase [Gordonia alkanivorans].	55.56	99	44	0	16	114	9	107	2e-31	119
rs:WP_027187662	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio cuneatus].	50.00	110	54	1	23	131	15	124	2e-31	119
rs:WP_025306691	phosphoribosyl-ATP pyrophosphatase [Thermocrinis ruber].	54.55	99	44	1	16	113	2	100	2e-31	121
rs:WP_028674841	phosphoribosyl-AMP cyclohydrolase [Salinispora arenicola].	54.64	97	44	0	18	114	35	131	2e-31	120
rs:WP_045921242	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium coryneforme].	56.12	98	43	0	15	112	17	114	2e-31	120
rs:WP_000233115	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Acinetobacter].	55.21	96	43	0	18	113	28	123	2e-31	119
rs:WP_012419663	phosphoribosyl-AMP cyclohydrolase [Akkermansia muciniphila].	54.81	104	46	1	19	121	29	132	2e-31	120
rs:WP_040958395	phosphoribosyl-AMP cyclohydrolase [Sinorhizobium fredii].	51.28	117	53	2	17	129	22	138	2e-31	120
rs:WP_012627114	phosphoribosyl-ATP pyrophosphatase [Cyanothece sp. PCC 7425].	58.76	97	39	1	18	113	20	116	2e-31	122
rs:WP_013031169	phosphoribosyl-AMP cyclohydrolase [Nitrosococcus halophilus].	52.48	101	47	1	18	117	8	108	2e-31	119
rs:WP_044213255	phosphoribosyl-ATP pyrophosphatase [Peptoclostridium difficile].	45.54	112	61	0	16	127	6	117	2e-31	121
rs:WP_028393590	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. FJAT-14515].	51.96	102	48	1	18	118	5	106	2e-31	122
rs:WP_032038043	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	2e-31	123
rs:WP_040164412	phosphoribosyl-AMP cyclohydrolase [Microbacterium sp. G3].	55.79	95	42	0	18	112	9	103	2e-31	119
rs:WP_029724645	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Sphingomonas].	59.41	101	41	0	19	119	14	114	2e-31	119
rs:WP_022004416	histidine biosynthesis bifunctional protein HisIE [Firmicutes bacterium CAG:194].	58.16	98	41	0	16	113	224	321	2e-31	124
rs:WP_033154124	phosphoribosyl-ATP diphosphatase [Pseudobutyrivibrio ruminis].	49.57	117	57	1	16	130	226	342	2e-31	125
rs:WP_028844413	phosphoribosyl-AMP cyclohydrolase [Thermodesulfovibrio thiophilus].	54.64	97	43	1	18	113	5	101	2e-31	119
rs:WP_046138798	phosphoribosyl-AMP cyclohydrolase [Devosia insulae].	54.72	106	44	2	19	120	25	130	2e-31	120
rs:WP_044414672	phosphoribosyl-AMP cyclohydrolase [Rhodopseudomonas palustris].	51.96	102	49	0	19	120	23	124	2e-31	120
rs:WP_030439425	phosphoribosyl-AMP cyclohydrolase [Actinoplanes subtropicus].	56.70	97	42	0	18	114	38	134	2e-31	120
rs:WP_017385377	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Acinetobacter].	55.67	97	42	1	18	113	10	106	2e-31	122
rs:WP_037400419	phosphoribosyl-AMP cyclohydrolase [Sinorhizobium fredii].	51.28	117	53	2	17	129	22	138	2e-31	120
rs:WP_026554303	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. 35W].	52.21	113	52	2	2	112	1	113	2e-31	119
tr:Q2PYM2_9BACT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	55.67	97	42	1	18	113	11	107	2e-31	119
rs:WP_027436248	hypothetical protein [Lachnospiraceae bacterium AB2028].	58.16	98	41	0	16	113	233	330	2e-31	125
rs:WP_015138886	phosphoribosyl-AMP cyclohydrolase [Nostoc sp. PCC 7524].	53.85	104	45	2	18	120	18	119	2e-31	122
rs:WP_028744526	phosphoribosyl-AMP cyclohydrolase [Rhizobium mesoamericanum].	52.10	119	51	3	17	131	23	139	2e-31	120
rs:WP_046322851	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium asteroides].	57.89	95	40	0	18	112	20	114	2e-31	119
rs:WP_038225977	phosphoribosyl-AMP cyclohydrolase [Xanthobacter sp. 126].	54.81	104	45	1	19	120	10	113	2e-31	120
rs:WP_039406235	phosphoribosyl-AMP cyclohydrolase [Pandoraea pulmonicola].	51.43	105	50	1	18	121	9	113	2e-31	119
rs:WP_021062718	phosphoribosyl-AMP cyclohydrolase [uncultured archaeon A07HR60].	53.00	100	47	0	18	117	15	114	2e-31	119
rs:WP_002772755	phosphoribosyl-ATP pyrophosphatase [Microcystis aeruginosa].	52.83	106	47	2	9	113	6	109	2e-31	121
rs:WP_034277858	phosphoribosyl-AMP cyclohydrolase [Amycolatopsis halophila].	53.70	108	45	1	18	125	9	111	2e-31	119
rs:WP_014208235	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Acinetobacter calcoaceticus/baumannii complex].	55.67	97	42	1	18	113	10	106	2e-31	122
rs:WP_047188399	phosphoribosyl-AMP cyclohydrolase [Microvirga vignae].	50.86	116	52	2	7	117	12	127	3e-31	119
rs:WP_031947219	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	3e-31	122
rs:WP_028141102	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium].	52.53	99	47	0	19	117	17	115	3e-31	119
rs:WP_042384553	phosphoribosyl-ATP pyrophosphatase [Geobacillus thermoglucosidasius].	49.50	101	51	0	14	114	2	102	3e-31	121
rs:WP_004590525	phosphoribosyl-AMP cyclohydrolase [Haloarcula japonica].	55.00	100	45	0	18	117	6	105	3e-31	119
rs:WP_042833750	phosphoribosyl-ATP pyrophosphatase [Thermoanaerobacter sp. YS13].	51.00	100	49	0	14	113	3	102	3e-31	122
sp:HIS3_ARTS2	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	56.84	95	41	0	18	112	21	115	3e-31	119
rs:WP_026575955	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. UNC438CL73TsuS30].	53.40	103	48	0	18	120	3	105	3e-31	121
rs:WP_019962514	hypothetical protein [Pannonibacter phragmitetus].	50.00	116	55	2	19	131	24	139	3e-31	120
rs:WP_047237452	phosphoribosyl-AMP cyclohydrolase [Chromobacterium subtsugae].	50.00	114	56	1	18	130	7	120	3e-31	119
rs:WP_032062861	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Acinetobacter calcoaceticus/baumannii complex].	55.67	97	42	1	18	113	10	106	3e-31	122
rs:WP_046108433	phosphoribosyl-AMP cyclohydrolase [Devosia geojensis].	55.05	109	45	2	20	124	26	134	3e-31	120
rs:WP_020091162	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Methylobacterium].	49.18	122	54	3	7	125	19	135	3e-31	119
rs:WP_034549501	phosphoribosyl-ATP diphosphatase, partial [Clostridiales bacterium VE202-09].	53.77	106	47	1	9	114	164	267	3e-31	125
rs:WP_020279446	phosphoribosyl-ATP diphosphatase [Geobacillus kaustophilus].	52.78	108	50	1	15	122	2	108	3e-31	121
rs:WP_046135581	phosphoribosyl-AMP cyclohydrolase [Devosia limi].	54.72	106	44	2	19	120	25	130	3e-31	120
rs:WP_028247086	phosphoribosyl-ATP diphosphatase [Pseudobutyrivibrio ruminis].	51.28	117	55	1	16	130	226	342	3e-31	125
rs:WP_031407129	phosphoribosyl-ATP pyrophosphatase [Geobacillus vulcani].	52.78	108	50	1	15	122	2	108	3e-31	121
sp:HIS3_UNCMA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	58.51	94	39	0	24	117	9	102	3e-31	119
rs:WP_003352071	phosphoribosyl-ATP pyrophosphatase [Bacillus methanolicus].	49.07	108	55	0	14	121	2	109	3e-31	122
rs:WP_016144177	phosphoribosyl-AMP cyclohydrolase [Acinetobacter pittii].	55.67	97	42	1	18	113	10	106	3e-31	122
rs:WP_027100912	phosphoribosyl-AMP cyclohydrolase [Comamonadaceae bacterium URHA0028].	51.00	100	45	1	18	113	7	106	3e-31	119
rs:WP_010186957	phosphoribosyl-AMP cyclohydrolase [Sphingomonas sp. PAMC 26605].	48.72	117	55	1	1	117	1	112	3e-31	119
rs:WP_045358479	imidazole glycerol phosphate synthase [Microcystis aeruginosa].	52.83	106	47	2	9	113	6	109	3e-31	121
rs:WP_027691466	phosphoribosyl-AMP cyclohydrolase [Rathayibacter toxicus].	58.06	93	39	0	20	112	15	107	3e-31	119
rs:WP_045276896	phosphoribosyl-AMP cyclohydrolase [Microbacterium ketosireducens].	52.94	102	48	0	11	112	5	106	3e-31	119
rs:WP_002739884	phosphoribosyl-ATP diphosphatase [Microcystis aeruginosa].	51.85	108	49	2	9	115	6	111	3e-31	121
rs:WP_018322162	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. WSM2793].	49.54	109	53	1	19	125	17	125	3e-31	119
rs:WP_035295785	phosphoribosyl-ATP pyrophosphatase [Brevibacillus thermoruber].	52.88	104	49	0	18	121	10	113	3e-31	121
rs:WP_019456882	phosphoribosyl-ATP diphosphatase [Acinetobacter sp. GG2].	54.64	97	43	1	18	113	10	106	3e-31	122
rs:WP_002743895	phosphoribosyl-ATP diphosphatase [Microcystis aeruginosa].	51.85	108	49	2	9	115	6	111	3e-31	121
rs:WP_028447677	phosphoribosyl-AMP cyclohydrolase [Chitinimonas koreensis].	48.25	114	58	1	18	130	7	120	3e-31	119
rs:WP_005065898	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Acinetobacter calcoaceticus/baumannii complex].	55.67	97	42	1	18	113	10	106	3e-31	122
rs:WP_002786821	phosphoribosyl-ATP pyrophosphatase [Microcystis aeruginosa].	51.85	108	49	2	9	115	6	111	3e-31	121
rs:WP_036595316	phosphoribosyl-ATP pyrophosphatase, partial [Paenibacillus sophorae].	51.92	104	50	0	18	121	19	122	3e-31	119
rs:WP_030093380	phosphoribosyl-AMP cyclohydrolase [Mycobacterium abscessus].	58.95	95	39	0	18	112	12	106	3e-31	119
rs:WP_035588964	phosphoribosyl-ATP pyrophosphatase [Hippea jasoniae].	51.40	107	52	0	16	122	6	112	3e-31	122
rs:WP_029678896	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium sp. 7101].	56.84	95	41	0	18	112	20	114	3e-31	119
rs:WP_042535055	phosphoribosyl-ATP pyrophosphatase [Anoxybacillus ayderensis].	53.61	97	45	0	17	113	2	98	3e-31	121
tr:E6N7G0_9ARCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	53.12	96	45	0	18	113	6	101	3e-31	118
rs:WP_009501357	phosphoribosyl-AMP cyclohydrolase [Moraxella macacae].	52.94	102	47	1	16	116	5	106	3e-31	123
rs:WP_003603912	phosphoribosyl-AMP cyclohydrolase [Methylobacterium extorquens].	55.34	103	44	1	17	117	21	123	3e-31	119
rs:WP_039251196	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	54.64	97	43	1	18	113	10	106	3e-31	122
rs:WP_031994166	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	3e-31	122
rs:WP_013777776	phosphoribosyl-ATP pyrophosphatase [Tepidanaerobacter acetatoxydans].	49.50	101	51	0	18	118	4	104	3e-31	121
rs:WP_004162874	phosphoribosyl-ATP pyrophosphatase [Microcystis aeruginosa].	51.85	108	49	2	9	115	6	111	3e-31	121
tr:D2R0U5_PIRSD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00006950}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	52.73	110	47	1	7	116	168	272	3e-31	124
tr:A0A0D7EFY9_RHOPL	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:KIZ39663.1};	51.96	102	49	0	19	120	10	111	3e-31	119
rs:WP_029423712	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	3e-31	122
rs:WP_007291096	phosphoribosyl-AMP cyclohydrolase [delta proteobacterium MLMS-1].	52.94	102	47	1	21	121	7	108	3e-31	119
rs:WP_031255649	phosphoribosyl-AMP cyclohydrolase [Curvibacter lanceolatus].	52.00	100	44	1	18	113	7	106	3e-31	119
rs:WP_043075325	phosphoribosyl-AMP cyclohydrolase [Methylobacterium radiotolerans].	48.76	121	55	2	2	120	7	122	3e-31	119
rs:WP_022142610	phosphoribosyl-ATP diphosphatase [Clostridium sp. CAG:230].	55.00	100	45	0	14	113	217	316	3e-31	125
rs:WP_045893339	phosphoribosyl-AMP cyclohydrolase [Clostridium botulinum].	57.78	90	38	0	25	114	18	107	3e-31	118
rs:WP_028480291	phosphoribosyl-AMP cyclohydrolase [Nesiotobacter exalbescens].	56.44	101	42	1	19	117	28	128	3e-31	120
rs:WP_021682237	phosphoribosyl-AMP cyclohydrolase [Ruminococcus callidus].	55.79	95	42	0	20	114	13	107	3e-31	119
rs:WP_006192378	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Selenomonas].	55.00	100	44	1	13	112	5	103	3e-31	122
tr:W4TQ26_PROAA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	58.62	87	36	0	26	112	1	87	3e-31	118
rs:WP_016173426	phosphoribosyl-ATP diphosphatase [Enterococcus dispar].	52.53	99	47	0	14	112	2	100	3e-31	121
tr:H5SPJ2_9ZZZZ	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:BAL58078.1};	52.08	96	46	0	18	113	7	102	3e-31	119
rs:WP_032030940	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	3e-31	122
rs:WP_001066565	hypothetical protein [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	3e-31	122
rs:WP_023495350	phosphoribosyl-AMP cyclohydrolase [Methyloglobulus morosus].	51.46	103	49	1	18	119	9	111	3e-31	119
rs:WP_033158585	phosphoribosyl-AMP cyclohydrolase [Methylomonas sp. LW13].	46.49	114	60	1	18	130	9	122	3e-31	119
rs:WP_019180698	hypothetical protein [Microbacterium yannicii].	55.67	97	43	0	16	112	10	106	3e-31	119
tr:A0A087C0J8_9BIFI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.89	95	40	0	18	112	46	140	3e-31	120
rs:WP_046169620	phosphoribosyl-AMP cyclohydrolase [Devosia psychrophila].	55.67	97	41	1	19	113	25	121	3e-31	119
rs:WP_016203876	phosphoribosyl-AMP cyclohydrolase [Bacillus nealsonii].	50.00	110	55	0	18	127	6	115	3e-31	121
rs:WP_012410443	phosphoribosyl-ATP pyrophosphatase [Nostoc punctiforme].	54.55	99	44	1	18	115	18	116	3e-31	121
rs:WP_040321136	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Actinomyces].	51.89	106	51	0	15	120	8	113	3e-31	119
rs:WP_044736841	phosphoribosyl-ATP pyrophosphatase [Geobacillus kaustophilus].	52.78	108	50	1	15	122	2	108	3e-31	121
rs:WP_030450267	phosphoribosyl-AMP cyclohydrolase [Herbidospora cretacea].	55.79	95	42	0	18	112	11	105	3e-31	119
tr:C0QTZ3_PERMH	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	49.02	102	52	0	12	113	3	104	3e-31	121
rs:WP_031966351	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	3e-31	122
tr:M5SU44_9PLAN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	53.27	107	49	1	12	117	37	143	3e-31	120
tr:E6PNN4_9ZZZZ	SubName: Full=Phosphoribosyl-AMP cyclohydrolase (PRA-CH) {ECO:0000313|EMBL:CBH96536.1}; EC=3.5.4.19 {ECO:0000313|EMBL:CBH96536.1};	47.83	115	56	1	20	130	9	123	3e-31	119
rs:WP_027478375	phosphoribosyl-AMP cyclohydrolase [Curvibacter gracilis].	52.00	100	44	1	18	113	7	106	3e-31	119
rs:WP_033430667	phosphoribosyl-AMP cyclohydrolase [Saccharothrix syringae].	58.95	95	39	0	18	112	13	107	3e-31	118
rs:WP_029687516	phosphoribosyl-ATP pyrophosphatase [Thermoanaerobacter sp. A7A].	51.00	100	49	0	14	113	3	102	3e-31	121
rs:WP_026454127	phosphoribosyl-AMP cyclohydrolase [Actinopolyspora iraqiensis].	54.63	108	44	1	18	125	13	115	3e-31	119
rs:WP_014921432	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. Rue61a].	54.64	97	44	0	16	112	29	125	3e-31	119
rs:WP_006301838	phosphoribosyl-ATP pyrophosphatase [Aminomonas paucivorans].	55.24	105	46	1	18	121	7	111	3e-31	121
rs:WP_029631647	imidazole glycerol phosphate synthase [[Scytonema hofmanni] UTEX B 1581].	53.54	99	45	1	18	115	14	112	3e-31	121
rs:WP_041360160	phosphoribosyl-AMP cyclohydrolase [Nitrosomonas sp. Is79A3].	46.55	116	61	1	16	130	7	122	3e-31	119
rs:WP_034316609	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. DW5-4].	56.70	97	42	0	16	112	5	101	3e-31	121
tr:S0K9H6_ENTAV	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	46.96	115	61	0	16	130	2	116	3e-31	121
rs:WP_015460157	phosphoribosyl-AMP cyclohydrolase [Sphingomonas sp. MM-1].	50.50	101	50	0	19	119	14	114	3e-31	119
rs:WP_002751320	phosphoribosyl-ATP pyrophosphatase [Microcystis aeruginosa].	51.85	108	49	2	9	115	6	111	3e-31	121
rs:WP_024971275	imidazole glycerol phosphate synthase [Microcystis aeruginosa].	52.83	106	47	2	9	113	6	109	3e-31	121
rs:WP_014519259	phosphoribosyl-AMP cyclohydrolase [Clostridium botulinum].	56.52	92	40	0	23	114	16	107	3e-31	118
rs:WP_002764104	phosphoribosyl-ATP pyrophosphatase [Microcystis aeruginosa].	51.85	108	49	2	9	115	6	111	3e-31	121
rs:WP_002793015	phosphoribosyl-ATP pyrophosphatase [Microcystis aeruginosa].	52.83	106	47	2	9	113	6	109	3e-31	121
rs:WP_007029956	phosphoribosyl-AMP cyclohydrolase [Amycolatopsis decaplanina].	56.70	97	42	0	18	114	11	107	3e-31	119
rs:WP_002156965	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Acinetobacter calcoaceticus/baumannii complex].	55.67	97	42	1	18	113	10	106	3e-31	122
rs:WP_034876797	phosphoribosyl-ATP pyrophosphatase [Enterococcus avium].	46.96	115	61	0	16	130	3	117	3e-31	121
sp:HIS3_CLOBJ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	57.78	90	38	0	25	114	18	107	3e-31	118
rs:WP_037332911	phosphoribosyl-AMP cyclohydrolase [Salinisphaera hydrothermalis].	47.15	123	61	4	10	130	6	126	3e-31	119
sp:HIS3_HALMA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	54.00	100	46	0	18	117	6	105	3e-31	119
rs:WP_002781146	histidine biosynthesis protein HisIE [Microcystis aeruginosa].	51.85	108	49	2	9	115	6	111	3e-31	121
rs:WP_047165682	phosphoribosyl-AMP cyclohydrolase [Sphingomonas sp. Y57].	45.53	123	62	1	1	123	1	118	3e-31	119
rs:WP_037015647	phosphoribosyl-AMP cyclohydrolase [Rhizobiales bacterium YIM 77505].	56.73	104	43	1	19	120	26	129	3e-31	119
rs:WP_026108200	phosphoribosyl-AMP cyclohydrolase [beta proteobacterium L13].	49.12	114	57	1	18	130	7	120	3e-31	119
tr:W2U4D5_9DEIN	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	50.98	102	50	0	18	119	1	102	3e-31	121
tr:F2UZF0_ACTVI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	51.89	106	51	0	15	120	13	118	3e-31	119
rs:WP_008039274	phosphoribosyl-AMP cyclohydrolase [Bartonella tamiae].	56.70	97	40	1	19	113	16	112	3e-31	119
rs:WP_026021336	phosphoribosyl-ATP pyrophosphatase [Paenibacillus senegalensis].	48.31	118	51	1	18	125	12	129	3e-31	121
rs:WP_024933655	phosphoribosyl-AMP cyclohydrolase [Clostridium botulinum].	57.78	90	38	0	25	114	18	107	3e-31	118
rs:WP_032009939	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	3e-31	122
rs:WP_002804335	phosphoribosyl-ATP pyrophosphatase [Microcystis aeruginosa].	52.83	106	47	2	9	113	6	109	3e-31	121
tr:X1SK11_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_L06040 {ECO:0000313|EMBL:GAI79471.1};	54.08	98	45	0	16	113	3	100	3e-31	118
rs:WP_015865035	phosphoribosyl-ATP pyrophosphatase [Geobacillus sp. WCH70].	52.00	100	48	0	13	112	1	100	3e-31	121
sp:HIS3_RENSM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	55.79	95	42	0	18	112	20	114	3e-31	119
rs:WP_013652384	phosphoribosyl-AMP cyclohydrolase [Polymorphum gilvum].	46.97	132	60	4	8	131	10	139	3e-31	119
rs:WP_042168836	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. G1].	52.43	103	49	0	15	117	11	113	3e-31	122
rs:WP_044352747	phosphoribosyl-AMP cyclohydrolase [Desulfarculus sp. SPR].	57.84	102	41	2	24	124	11	111	4e-31	119
rs:WP_007025760	phosphoribosyl-AMP cyclohydrolase [Saccharomonospora paurometabolica].	54.63	108	44	1	18	125	13	115	4e-31	119
rs:WP_032059210	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_001066567	hypothetical protein [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_009772238	phosphoribosyl-AMP cyclohydrolase [marine actinobacterium PHSC20C1].	59.57	94	38	0	19	112	18	111	4e-31	119
rs:WP_013327657	phosphoribosyl-ATP pyrophosphatase [Sulfurimonas autotrophica].	53.68	95	44	0	25	119	15	109	4e-31	121
rs:WP_045741316	phosphoribosyl-AMP cyclohydrolase [Actinoplanes rectilineatus].	56.84	95	41	0	18	112	25	119	4e-31	119
rs:WP_010615151	phosphoribosyl-AMP cyclohydrolase [Actinomyces oris].	51.89	106	51	0	15	120	8	113	4e-31	119
rs:WP_001061922	hypothetical protein [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_022877499	phosphoribosyl-AMP cyclohydrolase [Microbacterium sp. B19].	55.79	95	42	0	18	112	9	103	4e-31	118
tr:S3I0J6_9RHIZ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.10	119	51	3	17	131	22	138	4e-31	119
rs:WP_019279838	phosphoribosyl-AMP cyclohydrolase [Rhizobium grahamii].	52.10	119	51	3	17	131	23	139	4e-31	119
rs:WP_044732609	phosphoribosyl-ATP pyrophosphatase [Geobacillus kaustophilus].	52.78	108	50	1	15	122	2	108	4e-31	121
tr:B0VLT2_ACIBS	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_038991804	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. W1].	57.73	97	41	0	16	112	23	119	4e-31	119
rs:WP_042077124	phosphoribosyl-ATP diphosphatase [Acinetobacter nosocomialis].	55.67	97	42	1	18	113	10	106	4e-31	122
sp:HIS3_METTH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	54.37	103	46	1	19	121	17	118	4e-31	119
rs:WP_022515791	imidazole glycerol phosphate synthase subunit HisF [Roseburia sp. CAG:182].	55.10	98	44	0	16	113	226	323	4e-31	125
tr:T0YXA5_9ZZZZ	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:EQD40256.1}; EC=3.5.4.19 {ECO:0000313|EMBL:EQD40256.1};	53.47	101	46	1	18	117	17	117	4e-31	119
rs:WP_032009799	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_040751406	phosphoribosyl-AMP cyclohydrolase [Tetrasphaera elongata].	57.89	95	40	0	18	112	12	106	4e-31	118
rs:WP_007567355	phosphoribosyl-AMP cyclohydrolase [Methylobacterium sp. GXF4].	51.38	109	51	1	15	121	22	130	4e-31	119
rs:WP_038485021	phosphoribosyl-AMP cyclohydrolase [Collimonas arenae].	50.49	103	50	1	16	117	8	110	4e-31	119
rs:WP_032018784	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_031996948	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_004699051	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. NIPH 973].	54.64	97	43	1	18	113	10	106	4e-31	122
rs:WP_015021755	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium asteroides].	56.84	95	41	0	18	112	20	114	4e-31	119
rs:WP_020755648	phosphoribosyl-AMP cyclohydrolase [Geobacillus sp. WSUCF1].	53.70	108	49	1	15	122	2	108	4e-31	121
rs:WP_017769923	phosphoribosyl-AMP cyclohydrolase [Streptococcus agalactiae].	56.67	90	39	0	24	113	11	100	4e-31	118
rs:WP_035387863	phosphoribosyl-AMP cyclohydrolase [Exiguobacterium sp. NG55].	52.00	100	48	0	18	117	10	109	4e-31	118
rs:WP_045544612	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_001066566	hypothetical protein [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_029639000	phosphoribosyl-AMP cyclohydrolase [alpha proteobacterium Mf 1.05b.01].	46.96	115	59	1	19	131	25	139	4e-31	119
rs:WP_043119683	phosphoribosyl-AMP cyclohydrolase [Sinomonas sp. MUSC 117].	56.84	95	41	0	18	112	36	130	4e-31	119
rs:WP_008730332	phosphoribosyl-AMP cyclohydrolase [Actinomyces massiliensis].	55.10	98	44	0	15	112	8	105	4e-31	118
rs:WP_002062650	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	4e-31	122
sp:HIS3_SPHAL	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	55.56	99	44	0	19	117	14	112	4e-31	119
rs:WP_046486901	phosphoribosyl-AMP cyclohydrolase [Methylophilaceae bacterium MMS-2-53].	49.51	103	51	1	17	118	6	108	4e-31	119
rs:WP_040430863	phosphoribosyl-AMP cyclohydrolase, partial [Corynebacterium nuruki].	47.83	115	57	1	1	112	1	115	4e-31	118
rs:WP_035283425	phosphoribosyl-AMP cyclohydrolase [Actinokineospora sp. EG49].	58.95	95	39	0	18	112	15	109	4e-31	118
rs:WP_039754487	imidazole glycerol phosphate synthase [Hassallia byssoidea].	53.54	99	45	1	18	115	14	112	4e-31	121
rs:WP_038045823	imidazole glycerol phosphate synthase [Thermus caliditerrae].	50.47	107	53	0	13	119	1	107	4e-31	121
rs:WP_035780030	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. H14].	55.79	95	42	0	18	112	25	119	4e-31	119
rs:WP_001066572	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_032039805	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	4e-31	122
tr:T3DFL2_PEPDI	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	45.54	112	61	0	16	127	18	129	4e-31	121
rs:WP_014704540	phosphoribosyl-AMP cyclohydrolase [Methylophaga frappieri].	48.25	114	58	1	18	130	8	121	4e-31	119
rs:WP_018575657	hypothetical protein [Oligella ureolytica].	54.64	97	43	1	18	113	7	103	4e-31	119
rs:WP_001066570	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_001066569	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_002132810	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_001066574	hypothetical protein [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_001066573	hypothetical protein [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_016743744	phosphoribosyl-AMP cyclohydrolase [Sphingomonas wittichii].	47.01	117	57	1	1	117	1	112	4e-31	118
rs:WP_025116553	phosphoribosyl-ATP pyrophosphatase [Lysinibacillus fusiformis].	49.04	104	53	0	18	121	5	108	4e-31	121
rs:WP_026099957	imidazole glycerol phosphate synthase [Microchaete sp. PCC 7126].	54.55	99	44	1	18	115	18	116	4e-31	121
rs:WP_041137414	phosphoribosyl-ATP diphosphatase [Sulfurovum sp. AS07-7].	49.54	109	53	1	18	126	7	113	4e-31	121
tr:F3KXK9_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	46.67	120	57	1	18	130	18	137	4e-31	119
rs:WP_008230287	phosphoribosyl-AMP cyclohydrolase [Richelia intracellularis].	56.70	97	41	1	20	115	20	116	4e-31	121
rs:WP_025917072	phosphoribosyl-AMP cyclohydrolase [Herminiimonas sp. CN].	49.51	103	51	1	16	117	9	111	4e-31	119
rs:WP_024434048	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_010408542	phosphoribosyl-AMP cyclohydrolase [Sphingomonas echinoides].	52.53	99	47	0	19	117	14	112	4e-31	118
rs:WP_007272683	phosphoribosyl-AMP cyclohydrolase [Arthrobacter gangotriensis].	56.70	97	42	0	16	112	23	119	4e-31	119
rs:WP_004932512	phosphoribosyl-AMP cyclohydrolase [Acinetobacter soli].	53.00	100	46	1	18	116	10	109	4e-31	122
rs:WP_006720181	phosphoribosyl-AMP cyclohydrolase [Collinsella stercoris].	54.00	100	46	0	18	117	6	105	4e-31	118
rs:WP_010190469	phosphoribosyl-AMP cyclohydrolase [Corynebacterium aurimucosum].	60.00	95	37	1	18	112	31	124	4e-31	119
rs:WP_009587200	phosphoribosyl-ATP diphosphatase [Acinetobacter sp. WC-743].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_046760394	phosphoribosyl-ATP diphosphatase [Acinetobacter sp. Ag2].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_002126487	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_031978478	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_009768902	phosphoribosyl-AMP cyclohydrolase [Oscillatoriales cyanobacterium JSC-12].	56.70	97	41	1	20	115	14	110	4e-31	121
rs:WP_020612314	phosphoribosyl-AMP cyclohydrolase [Spirochaeta bajacaliforniensis].	50.96	104	45	1	10	113	22	119	4e-31	118
rs:WP_015187235	phosphoribosyl-AMP cyclohydrolase [Gloeocapsa sp. PCC 7428].	54.64	97	43	1	18	113	17	113	4e-31	121
rs:WP_014703358	phosphoribosyl-AMP cyclohydrolase [Methylophaga frappieri].	53.77	106	47	1	19	122	27	132	4e-31	119
rs:WP_034950151	phosphoribosyl-AMP cyclohydrolase [Candidatus Accumulibacter sp. SK-02].	56.00	100	44	0	18	117	23	122	4e-31	119
rs:WP_036304326	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Methylomicrobium].	59.46	111	43	1	8	116	11	121	4e-31	119
tr:A0A069DKI5_9BACL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	53.12	96	45	0	18	113	10	105	4e-31	121
rs:WP_001066568	hypothetical protein [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_002296960	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	51.55	97	47	0	22	118	11	107	4e-31	118
rs:WP_046289987	phosphoribosyl-AMP cyclohydrolase [Pandoraea oxalativorans].	50.96	104	50	1	18	120	9	112	4e-31	119
rs:WP_004825354	phosphoribosyl-ATP diphosphatase [Acinetobacter bereziniae].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_019520320	hypothetical protein [Moraxella boevrei].	50.96	104	50	1	16	118	5	108	4e-31	122
rs:WP_027882791	imidazole glycerol phosphate synthase [Meiothermus rufus].	49.50	101	51	0	13	113	1	101	4e-31	120
rs:WP_017234576	phosphoribosyl-AMP cyclohydrolase [Pandoraea sp. B-6].	50.48	105	51	1	18	121	9	113	4e-31	119
rs:WP_039959818	hypothetical protein [[Ruminococcus] gnavus].	52.68	112	51	1	2	113	215	324	4e-31	124
rs:WP_031540666	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. MB2021].	48.18	110	57	0	14	123	2	111	4e-31	121
rs:WP_039853851	phosphoribosyl-AMP cyclohydrolase [Hylemonella gracilis].	46.67	120	57	1	18	130	14	133	4e-31	119
rs:WP_026472417	phosphoribosyl-ATP diphosphatase [Alkanindiges illinoisensis].	55.00	100	44	1	18	116	8	107	4e-31	122
rs:WP_009244718	imidazole glycerol phosphate synthase [Ruminococcus gnavus CAG:126].	52.68	112	51	1	2	113	215	324	4e-31	124
tr:H8GK08_METAL	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	59.46	111	43	1	8	116	13	123	4e-31	119
rs:WP_016803970	phosphoribosyl-ATP diphosphatase [Acinetobacter nosocomialis].	55.67	97	42	1	18	113	10	106	4e-31	122
rs:WP_021849149	hypothetical protein [Firmicutes bacterium CAG:791].	54.46	101	46	0	13	113	226	326	5e-31	124
rs:WP_019243005	hypothetical protein [Bacillus massilioanorexius].	52.63	95	45	0	18	112	6	100	5e-31	121
rs:WP_026912568	phosphoribosyl-ATP diphosphatase [Patulibacter minatonensis].	52.48	101	48	0	15	115	2	102	5e-31	121
rs:WP_002273795	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	52.63	95	45	0	22	116	11	105	5e-31	118
rs:WP_006569518	phosphoribosyl-ATP pyrophosphatase [Thermoanaerobacter siderophilus].	51.00	100	49	0	14	113	3	102	5e-31	121
rs:WP_012834676	phosphoribosyl-AMP cyclohydrolase [Gordonia bronchialis].	54.72	106	47	1	10	114	2	107	5e-31	118
rs:WP_030334436	phosphoribosyl-AMP cyclohydrolase [Micromonospora parva].	54.64	97	44	0	18	114	37	133	5e-31	119
rs:WP_005034311	phosphoribosyl-ATP diphosphatase [Acinetobacter bereziniae].	55.67	97	42	1	18	113	10	106	5e-31	122
rs:WP_022032492	histidine biosynthesis protein HisIE [Clostridium hathewayi CAG:224].	58.42	101	41	1	18	117	231	331	5e-31	124
rs:WP_022155052	hypothetical protein [Firmicutes bacterium CAG:65].	58.33	96	40	0	18	113	229	324	5e-31	124
rs:WP_045890695	phosphoribosyl-AMP cyclohydrolase, partial [Clostridium botulinum].	57.78	90	38	0	25	114	3	92	5e-31	117
tr:X0VAX3_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_S15105 {ECO:0000313|EMBL:GAG09628.1}; Flags: Fragment;	55.91	93	41	0	26	118	1	93	5e-31	117
sp:HIS3_SPHWW	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	47.01	117	57	1	1	117	1	112	5e-31	118
rs:WP_034608652	phosphoribosyl-AMP cyclohydrolase [Cellulomonas sp. URHD0024].	56.84	95	41	0	18	112	17	111	5e-31	119
rs:WP_027513168	phosphoribosyl-AMP cyclohydrolase [Rhizobium sullae].	50.43	117	56	1	17	131	23	139	5e-31	119
rs:WP_041530984	phosphoribosyl-ATP pyrophosphatase [Persephonella marina].	52.08	96	46	0	18	113	6	101	5e-31	120
rs:WP_005013250	phosphoribosyl-AMP cyclohydrolase [Acinetobacter bouvetii].	54.64	97	43	1	18	113	10	106	5e-31	122
tr:S2Z6S8_9CORY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00006950}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216}; EC=4.1.3.- {ECO:0000256|SAAS:SAAS00088643};	54.74	95	42	1	18	112	264	357	5e-31	124
rs:WP_045008328	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. LTSP857].	50.46	109	52	1	19	125	17	125	5e-31	119
rs:WP_019560552	phosphoribosyl-AMP cyclohydrolase [Caldimonas manganoxidans].	49.06	106	50	1	18	119	7	112	5e-31	118
rs:WP_005222122	phosphoribosyl-AMP cyclohydrolase [Marichromatium purpuratum].	50.86	116	55	2	17	130	14	129	5e-31	119
rs:WP_010217092	phosphoribosyl-AMP cyclohydrolase [Sphingomonas sp. PAMC 26621].	54.90	102	46	0	19	120	14	115	5e-31	118
rs:WP_042113348	phosphoribosyl-AMP cyclohydrolase [Pandoraea apista].	50.48	105	51	1	18	121	9	113	5e-31	119
rs:WP_022857470	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium pseudolongum].	54.64	97	44	0	16	112	18	114	5e-31	119
rs:WP_028515665	phosphoribosyl-AMP cyclohydrolase [Ruminococcus flavefaciens].	51.46	103	50	0	20	122	13	115	5e-31	118
rs:WP_014749325	phosphoribosyl-AMP cyclohydrolase [Advenella kashmirensis].	50.00	116	53	3	20	130	9	124	5e-31	118
rs:WP_032031692	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	5e-31	122
rs:WP_033169439	phosphoribosyl-ATP pyrophosphatase [Selenomonas sp. ND2010].	53.47	101	46	1	12	112	4	103	5e-31	121
rs:WP_015206649	phosphoribosyl-AMP cyclohydrolase [Cylindrospermum stagnale].	54.55	99	44	1	18	115	18	116	5e-31	121
rs:WP_006275658	phosphoribosyl-ATP pyrophosphatase [Cylindrospermopsis raciborskii].	55.56	99	43	1	18	115	18	116	5e-31	121
tr:G2G069_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	48.15	108	55	1	13	119	9	116	5e-31	121
rs:WP_014328118	phosphoribosyl-AMP cyclohydrolase [Sinorhizobium fredii].	51.28	117	53	2	17	129	22	138	5e-31	119
rs:WP_029994165	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Sphingomonas].	47.01	117	57	1	1	117	1	112	5e-31	118
rs:WP_004883536	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Acinetobacter calcoaceticus/baumannii complex].	55.67	97	42	1	18	113	10	106	5e-31	122
rs:WP_022516905	hypothetical protein [Roseburia sp. CAG:100].	56.12	98	43	0	16	113	224	321	5e-31	124
rs:WP_008234360	phosphoribosyl-AMP cyclohydrolase [Richelia intracellularis].	56.70	97	41	1	20	115	20	116	5e-31	121
rs:WP_015714776	phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis].	56.84	95	41	0	18	112	7	101	5e-31	120
tr:W8YQ48_9BACL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	51.40	107	52	0	8	114	9	115	5e-31	121
rs:WP_006560777	phosphoribosyl-ATP pyrophosphatase [Oscillochloris trichoides].	57.29	96	41	0	18	113	1	96	5e-31	120
rs:WP_040413360	phosphoribosyl-ATP pyrophosphatase [Desulfosporosinus sp. OT].	48.15	108	55	1	13	119	15	122	5e-31	121
rs:WP_016859063	phosphoribosyl-ATP pyrophosphatase [Fischerella muscicola].	53.54	99	45	1	18	115	18	116	5e-31	121
tr:A7B4I5_RUMGN	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	52.68	112	51	1	2	113	228	337	5e-31	124
rs:WP_015685259	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. S23321].	53.54	99	46	0	19	117	17	115	5e-31	119
rs:WP_027486308	phosphoribosyl-AMP cyclohydrolase [Rhizobium undicola].	52.10	119	51	3	17	129	23	141	5e-31	119
rs:WP_039620808	phosphoribosyl-ATP diphosphatase [Acinetobacter harbinensis].	54.64	97	43	1	18	113	10	106	5e-31	122
rs:WP_039908765	phosphoribosyl-AMP cyclohydrolase [Micromonospora lupini].	54.64	97	44	0	18	114	37	133	5e-31	119
rs:WP_037254840	phosphoribosyl-AMP cyclohydrolase [Rhodococcus rhodnii].	57.89	95	40	0	18	112	11	105	5e-31	118
rs:WP_003081351	phosphoribosyl-AMP cyclohydrolase [Streptococcus macacae].	53.19	94	44	0	21	114	10	103	5e-31	118
rs:WP_046697379	phosphoribosyl-AMP cyclohydrolase [Moraxella bovoculi].	58.16	98	40	1	17	113	6	103	5e-31	122
rs:WP_009052787	phosphoribosyl-ATP pyrophosphatase [Thermoanaerobacter sp. X561].	51.00	100	49	0	14	113	3	102	5e-31	121
rs:WP_016142361	phosphoribosyl-AMP cyclohydrolase [Acinetobacter pittii].	55.67	97	42	1	18	113	10	106	5e-31	122
rs:WP_032054286	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	55.67	97	42	1	18	113	10	106	5e-31	122
rs:WP_022263064	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [Butyrivibrio sp. CAG:318].	51.96	102	49	0	12	113	243	344	5e-31	124
rs:WP_044257516	phosphoribosyl-AMP cyclohydrolase [Rhodopirellula sp. SWK7].	53.15	111	50	2	12	120	3	113	5e-31	118
rs:WP_036629021	phosphoribosyl-ATP pyrophosphatase [Paenibacillus macerans].	54.64	97	44	0	17	113	7	103	5e-31	122
rs:WP_007525111	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio sp. A2].	50.78	128	60	2	5	131	3	128	5e-31	118
rs:WP_021988199	phosphoribosyl-ATP diphosphatase [Odoribacter sp. CAG:788].	54.08	98	45	0	14	111	2	99	5e-31	120
rs:WP_004920433	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Acinetobacter].	54.64	97	43	1	18	113	10	106	5e-31	122
rs:WP_030489006	phosphoribosyl-AMP cyclohydrolase [Micromonospora chokoriensis].	54.64	97	44	0	18	114	37	133	6e-31	119
rs:WP_046698839	phosphoribosyl-AMP cyclohydrolase [Moraxella bovoculi].	58.16	98	40	1	17	113	6	103	6e-31	122
rs:WP_037430047	phosphoribosyl-AMP cyclohydrolase [Sinorhizobium fredii].	51.28	117	53	2	17	129	22	138	6e-31	119
rs:WP_046701592	phosphoribosyl-AMP cyclohydrolase [Moraxella bovoculi].	58.16	98	40	1	17	113	6	103	6e-31	122
rs:WP_035083460	phosphoribosyl-AMP cyclohydrolase [Devosia riboflavina].	56.44	101	42	1	19	117	25	125	6e-31	119
rs:WP_040854009	phosphoribosyl-AMP cyclohydrolase [Phyllobacterium sp. YR531].	53.15	111	48	2	19	125	10	120	6e-31	118
rs:WP_022399569	phosphoribosyl-ATP diphosphatase [Roseburia sp. CAG:471].	46.96	115	59	1	1	113	1	115	6e-31	118
rs:WP_009986064	phosphoribosyl-AMP cyclohydrolase [Ruminococcus flavefaciens].	51.96	102	49	0	20	121	13	114	6e-31	118
rs:WP_028579174	phosphoribosyl-AMP cyclohydrolase [Desulfobulbus japonicus].	48.65	111	56	1	21	130	9	119	6e-31	118
rs:WP_035698167	phosphoribosyl-ATP pyrophosphatase [Atribacteria bacterium SCGC AAA255-N14].	49.09	110	55	1	18	126	5	114	6e-31	121
rs:WP_036077752	phosphoribosyl-AMP cyclohydrolase [Listeria cornellensis].	52.83	106	49	1	17	122	2	106	6e-31	117
rs:WP_017178519	phosphoribosyl-AMP cyclohydrolase [Actinomyces timonensis].	55.00	100	45	0	15	114	18	117	6e-31	118
tr:E1VX17_ARTAR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	56.84	95	41	0	18	112	25	119	6e-31	118
rs:WP_018239542	phosphoribosyl-AMP cyclohydrolase [Ensifer sp. BR816].	52.21	113	50	2	17	125	22	134	6e-31	119
rs:WP_006612925	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. ORS 285].	53.54	99	46	0	19	117	17	115	6e-31	119
tr:J2VX88_9RHIZ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	53.15	111	48	2	19	125	25	135	6e-31	118
rs:WP_007288209	phosphoribosyl-ATP pyrophosphatase [Thermosinus carboxydivorans].	51.96	102	49	0	11	112	3	104	6e-31	120
rs:WP_029356363	phosphoribosyl-AMP cyclohydrolase [Bosea sp. 117].	52.63	114	47	1	14	120	21	134	6e-31	119
rs:WP_034169745	phosphoribosyl-ATP diphosphatase [Acinetobacter sp. YZS-X1-1].	53.77	106	47	2	18	121	10	115	6e-31	122
tr:A6BDW3_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	54.29	105	46	1	9	113	222	324	6e-31	124
rs:WP_006437808	phosphoribosyl-AMP cyclohydrolase [Gordonia amicalis].	55.67	97	43	0	18	114	11	107	6e-31	118
rs:WP_019553356	hypothetical protein [Propionispira raffinosivorans].	49.57	115	55	2	14	126	2	115	6e-31	121
rs:WP_038972378	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. CCBAU 15635].	52.53	99	47	0	19	117	17	115	6e-31	119
rs:WP_020158958	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Methylobacter].	46.49	114	60	1	18	130	9	122	6e-31	118
rs:WP_044939499	phosphoribosyl-ATP diphosphatase [Blautia schinkii].	56.12	98	43	0	16	113	216	313	6e-31	124
rs:WP_037124126	phosphoribosyl-AMP cyclohydrolase [Rhizobium sp. CF097].	55.34	103	44	1	17	117	22	124	6e-31	119
rs:WP_029321343	imidazole glycerol phosphate synthase [Butyrivibrio sp. AE3004].	51.55	97	47	0	18	114	10	106	6e-31	120
rs:WP_018467950	hypothetical protein [Meiothermus timidus].	47.32	112	59	0	14	125	2	113	6e-31	120
rs:WP_046216303	phosphoribosyl-ATP pyrophosphatase [Paenibacillus wulumuqiensis].	51.96	102	49	0	15	116	12	113	6e-31	121
rs:WP_035351093	phosphoribosyl-ATP pyrophosphatase [Fictibacillus gelatini].	52.58	97	46	0	16	112	2	98	6e-31	120
sp:HIS3_NATPD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.08	96	46	0	18	113	5	100	6e-31	118
rs:WP_006867635	phosphoribosyl-AMP cyclohydrolase [Gordonia namibiensis].	55.67	97	43	0	18	114	11	107	6e-31	118
rs:WP_002853458	phosphoribosyl-AMP cyclohydrolase [Ruminococcus albus].	47.46	118	60	1	7	122	3	120	6e-31	118
rs:WP_022981046	phosphoribosyl-AMP cyclohydrolase [Ideonella sp. B508-1].	50.00	104	48	1	18	117	7	110	6e-31	118
rs:WP_015617062	phosphoribosyl-AMP cyclohydrolase [Clostridium pasteurianum].	54.26	94	43	0	24	117	15	108	6e-31	117
rs:WP_022046561	imidazole glycerol phosphate synthase subunit HisF [Roseburia sp. CAG:18].	51.40	107	52	0	10	116	221	327	6e-31	124
rs:WP_026420062	phosphoribosyl-AMP cyclohydrolase [Actinoalloteichus cyanogriseus].	57.89	95	40	0	18	112	14	108	6e-31	118
rs:WP_044164361	phosphoribosyl-ATP pyrophosphatase [Salinibacillus aidingensis].	44.80	125	63	1	11	129	1	125	7e-31	120
rs:WP_046410289	phosphoribosyl-AMP cyclohydrolase [Sphingomonas sp. Ag1].	50.94	106	51	1	19	123	14	119	7e-31	118
rs:WP_039844956	phosphoribosyl-AMP cyclohydrolase [Rhizobium gallicum].	49.57	117	57	1	17	131	23	139	7e-31	119
rs:WP_020449301	phosphoribosyl-AMP cyclohydrolase [Candidatus Methanomassiliicoccus intestinalis].	54.74	95	43	0	18	112	3	97	7e-31	120
rs:WP_039681673	imidazole glycerol phosphate synthase [Deinococcus swuensis].	52.63	114	53	1	14	126	9	122	7e-31	120
rs:WP_022415496	phosphoribosyl-ATP diphosphatase [Dorea longicatena CAG:42].	54.29	105	46	1	9	113	222	324	7e-31	124
rs:WP_021081797	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. DFCI-1].	48.67	113	58	0	19	131	19	131	7e-31	118
rs:WP_002284309	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	52.63	95	45	0	22	116	11	105	7e-31	117
rs:WP_029691659	phosphoribosyl-AMP cyclohydrolase [Streptococcus hyovaginalis].	51.92	104	44	1	10	113	3	100	7e-31	117
tr:A0A066UJV9_9GAMM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	58.16	98	40	1	17	113	7	104	7e-31	122
rs:WP_018111392	phosphoribosyl-ATP pyrophosphatase [Thermus igniterrae].	49.53	107	54	0	13	119	1	107	7e-31	120
rs:WP_030430920	phosphoribosyl-AMP cyclohydrolase [Allokutzneria albata].	53.77	106	47	1	18	121	12	117	7e-31	117
rs:WP_012831668	phosphoribosyl-ATP diphosphatase [Haliangium ochraceum].	49.50	101	51	0	20	120	20	120	7e-31	121
rs:WP_018854969	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Rhizobium].	51.26	119	52	3	17	131	23	139	7e-31	119
rs:WP_005922616	phosphoribosyl-ATP pyrophosphatase [Faecalibacterium prausnitzii].	54.55	99	45	0	18	116	3	101	7e-31	120
rs:WP_003515676	phosphoribosyl-AMP cyclohydrolase [Agrobacterium tumefaciens].	52.14	117	50	2	19	129	24	140	7e-31	119
rs:WP_038501237	phosphoribosyl-AMP cyclohydrolase [Basilea psittacipulmonis].	57.73	97	40	1	18	113	7	103	7e-31	118
rs:WP_036812495	phosphoribosyl-AMP cyclohydrolase [Polaromonas sp. CG9_12].	45.45	121	59	1	17	130	6	126	7e-31	118
rs:WP_006715064	phosphoribosyl-ATP pyrophosphatase [Desulfitobacterium metallireducens].	52.48	101	48	0	18	118	11	111	7e-31	121
rs:WP_021976579	phosphoribosyl-ATP pyrophosphohydrolase [Ruminococcus sp. CAG:17].	57.14	98	42	0	16	113	226	323	7e-31	124
rs:WP_022351816	hypothetical protein [Firmicutes bacterium CAG:534].	59.38	96	39	0	18	113	230	325	7e-31	124
rs:WP_044961526	imidazole glycerol phosphate synthase [Blautia sp. KLE 1732].	58.43	89	37	0	25	113	1	89	7e-31	120
rs:WP_002888928	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptococcus].	50.00	108	48	1	11	118	6	107	8e-31	117
rs:WP_012617374	phosphoribosyl-AMP cyclohydrolase [Methanosphaerula palustris].	53.06	98	46	0	20	117	5	102	8e-31	117
rs:WP_020376910	hypothetical protein [Candidatus Microthrix parvicella].	57.29	96	41	0	18	113	6	101	8e-31	117
sp:HIS3_NITMU	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	45.69	116	62	1	16	130	7	122	8e-31	118
rs:WP_019803007	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	51.55	97	47	0	22	118	11	107	8e-31	117
rs:WP_022106854	phosphoribosyl-ATP diphosphatase [Dialister sp. CAG:486].	45.38	119	62	1	14	129	5	123	8e-31	120
rs:WP_005804153	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Acinetobacter calcoaceticus/baumannii complex].	55.67	97	42	1	18	113	10	106	8e-31	121
rs:WP_034958759	phosphoribosyl-AMP cyclohydrolase [Erythrobacter longus].	52.63	95	45	0	19	113	21	115	8e-31	118
rs:WP_039893058	phosphoribosyl-ATP diphosphatase [[Clostridium] hathewayi].	57.43	101	42	1	18	117	231	331	8e-31	124
rs:WP_002270036	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	53.76	93	43	0	22	114	11	103	8e-31	117
rs:WP_002283675	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	52.63	95	45	0	22	116	11	105	8e-31	117
tr:A0A090Z8Q6_PAEMA	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	54.64	97	44	0	17	113	13	109	8e-31	121
rs:WP_047201832	phosphoribosyl-ATP pyrophosphatase, partial [Bacillus pumilus].	58.24	91	38	0	18	108	7	97	8e-31	117
sp:HIS2_CALS4	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	50.00	112	52	1	14	121	3	114	8e-31	120
rs:WP_044949544	hypothetical protein [[Ruminococcus] gnavus].	52.68	112	51	1	2	113	198	307	8e-31	124
rs:WP_041649818	phosphoribosyl-AMP cyclohydrolase [Arthrobacter arilaitensis].	56.84	95	41	0	18	112	5	99	8e-31	117
rs:WP_045445918	phosphoribosyl-AMP cyclohydrolase [Psychrobacter sp. JCM 18902].	54.55	99	44	1	16	113	8	106	8e-31	122
rs:WP_018040228	hypothetical protein [crenarchaeote SCGC AAA261-N23].	48.51	101	51	1	14	113	8	108	8e-31	117
rs:WP_036366806	phosphoribosyl-AMP cyclohydrolase [Moraxella bovoculi].	58.16	98	40	1	17	113	6	103	8e-31	121
rs:WP_018143651	hypothetical protein [Metascardovia criceti].	55.67	97	43	0	16	112	11	107	8e-31	118
rs:WP_007361746	phosphoribosyl-AMP cyclohydrolase [Opitutaceae bacterium TAV1].	52.34	107	48	1	15	118	16	122	8e-31	119
rs:WP_019804100	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	51.55	97	47	0	22	118	11	107	8e-31	117
rs:WP_002351146	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	52.63	95	45	0	22	116	11	105	8e-31	117
rs:WP_007632014	phosphoribosyl-AMP cyclohydrolase [Dietzia cinnamea].	57.73	97	41	0	18	114	14	110	8e-31	117
rs:WP_020961203	phosphoribosyl-ATP pyrophosphatase [Geobacillus sp. JF8].	52.78	108	50	1	15	122	2	108	8e-31	120
rs:WP_008961318	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. STM 3809].	50.00	110	52	1	19	125	17	126	8e-31	118
rs:WP_008006855	phosphoribosyl-AMP cyclohydrolase [Halorubrum lipolyticum].	51.00	100	49	0	18	117	13	112	8e-31	118
rs:WP_014004513	phosphoribosyl-AMP cyclohydrolase [Collimonas fungivorans].	49.51	103	51	1	16	117	8	110	8e-31	118
rs:WP_034473231	phosphoribosyl-AMP cyclohydrolase [Actinomyces johnsonii].	52.83	106	50	0	15	120	8	113	8e-31	117
rs:WP_019854685	hypothetical protein [Actinopolyspora mortivallis].	58.95	95	39	0	18	112	19	113	8e-31	118
tr:D3AQG1_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	57.43	101	42	1	18	117	238	338	8e-31	124
rs:WP_033316503	phosphoribosyl-ATP pyrophosphatase [Terrisporobacter glycolicus].	50.51	99	49	0	16	114	2	100	8e-31	120
rs:WP_015273459	phosphoribosyl-AMP cyclohydrolase [Liberibacter crescens].	49.58	119	58	1	12	128	14	132	8e-31	118
rs:WP_008966993	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. STM 3843].	50.00	110	52	1	19	125	16	125	8e-31	118
rs:WP_004896299	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Acinetobacter].	50.00	112	54	2	18	127	10	121	8e-31	121
rs:WP_002279745	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	52.63	95	45	0	22	116	11	105	8e-31	117
rs:WP_015152387	phosphoribosyl-AMP cyclohydrolase [Chroococcidiopsis thermalis].	53.40	103	45	2	18	119	19	119	8e-31	120
rs:WP_019312567	phosphoribosyl-AMP cyclohydrolase, partial [Streptococcus mutans].	53.19	94	44	0	21	114	10	103	8e-31	117
rs:WP_017313149	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Stigonematales].	53.54	99	45	1	18	115	18	116	8e-31	120
rs:WP_003092682	phosphoribosyl-AMP cyclohydrolase [Streptococcus vestibularis].	50.00	108	48	1	11	118	6	107	8e-31	117
rs:WP_046111064	phosphoribosyl-AMP cyclohydrolase [Aquincola tertiaricarbonis].	46.61	118	59	1	17	130	6	123	9e-31	118
rs:WP_015280757	phosphoribosyl-AMP cyclohydrolase [Thioflavicoccus mobilis].	48.65	111	56	1	17	126	10	120	9e-31	118
tr:C4L177_EXISA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	51.00	100	49	0	18	117	10	109	9e-31	117
rs:WP_027400216	phosphoribosyl-AMP cyclohydrolase [Anaerovorax odorimutans].	54.26	94	43	0	20	113	7	100	9e-31	117
rs:WP_028555570	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. URHA0014].	49.56	113	55	1	11	121	1	113	9e-31	120
sp:HIS3_LEIXX	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.96	104	51	0	9	112	2	105	9e-31	117
rs:WP_019804318	phosphoribosyl-AMP cyclohydrolase, partial [Streptococcus mutans].	51.55	97	47	0	22	118	11	107	9e-31	117
tr:X0REX8_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_L04438 {ECO:0000313|EMBL:GAF67449.1};	48.04	102	53	0	25	126	7	108	9e-31	120
rs:WP_030477025	phosphoribosyl-AMP cyclohydrolase [Lentzea albidocapillata].	57.89	95	40	0	18	112	13	107	9e-31	117
rs:WP_019103913	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Chromobacterium].	54.64	97	43	1	18	113	7	103	9e-31	118
rs:WP_015178673	phosphoribosyl-AMP cyclohydrolase [Oscillatoria nigro-viridis].	55.56	99	43	1	18	115	18	116	9e-31	120
rs:WP_002296437	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	53.19	94	44	0	21	114	10	103	9e-31	117
rs:WP_029423025	phosphoribosyl-ATP pyrophosphatase [Alicyclobacillus macrosporangiidus].	55.32	94	42	0	24	117	13	106	9e-31	121
rs:WP_030144885	phosphoribosyl-AMP cyclohydrolase [Spirillospora albida].	54.46	101	46	0	18	118	16	116	9e-31	117
rs:WP_045010537	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. LTSP849].	50.45	111	52	1	19	126	17	127	9e-31	118
rs:WP_042342363	imidazole glycerol phosphate synthase [Calothrix sp. PCC 7507].	53.54	99	45	1	18	115	18	116	9e-31	120
rs:WP_004994229	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Acinetobacter].	55.67	97	42	1	18	113	10	106	9e-31	121
rs:WP_002283127	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	53.19	94	44	0	21	114	10	103	9e-31	117
tr:F8GD80_NITSI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	46.55	116	61	1	16	130	33	148	9e-31	119
rs:WP_026765998	phosphoribosyl-ATP pyrophosphatase [Selenomonas ruminantium].	52.53	99	46	1	14	112	5	102	9e-31	120
rs:WP_033963312	phosphoribosyl-AMP cyclohydrolase [Sphingomonas sp. Ant H11].	51.52	99	48	0	19	117	14	112	9e-31	117
rs:WP_041292219	phosphoribosyl-AMP cyclohydrolase [Kineococcus radiotolerans].	58.95	95	39	0	18	112	12	106	9e-31	117
rs:WP_044919696	phosphoribosyl-ATP diphosphatase [Dorea longicatena].	54.29	105	46	1	9	113	211	313	9e-31	124
rs:WP_022050808	phosphoribosyl-AMP cyclohydrolase [Ruminococcus sp. CAG:254].	50.49	103	51	0	20	122	13	115	9e-31	117
tr:K9PMZ6_9CYAN	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	53.54	99	45	1	18	115	29	127	9e-31	120
tr:A0A074MHQ0_ERYLO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.63	95	45	0	19	113	15	109	9e-31	117
rs:WP_027892818	imidazole glycerol phosphate synthase [Meiothermus chliarophilus].	48.21	112	53	1	18	124	6	117	9e-31	120
rs:WP_004697654	phosphoribosyl-AMP cyclohydrolase [Veillonella parvula].	55.32	94	42	0	24	117	10	103	9e-31	117
rs:WP_044924197	phosphoribosyl-ATP diphosphatase [Dorea longicatena].	54.29	105	46	1	9	113	211	313	9e-31	124
rs:WP_020621073	hypothetical protein [Paenibacillus daejeonensis].	52.00	100	48	0	18	117	12	111	9e-31	120
tr:S7VXW6_9MICO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.89	95	40	0	18	112	17	111	9e-31	117
rs:WP_041918025	phosphoribosyl-AMP cyclohydrolase, partial [Exiguobacterium sp. AT1b].	51.52	99	48	0	18	116	10	108	9e-31	117
rs:WP_044139387	phosphoribosyl-ATP pyrophosphatase [Bacillus pumilus].	54.64	97	44	0	16	112	5	101	9e-31	120
rs:WP_036800295	phosphoribosyl-AMP cyclohydrolase [Porphyrobacter sp. HL-46].	49.50	101	51	0	19	119	20	120	9e-31	118
rs:WP_024783048	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	53.68	95	44	0	22	116	11	105	1e-30	117
rs:WP_004787175	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. NIPH 899].	53.77	106	47	2	18	121	10	115	1e-30	121
rs:WP_023485020	phosphoribosyl-AMP cyclohydrolase [Paenibacillus larvae].	52.04	98	47	0	15	112	10	107	1e-30	120
rs:WP_019318332	phosphoribosyl-AMP cyclohydrolase, partial [Streptococcus mutans].	53.19	94	44	0	21	114	10	103	1e-30	117
rs:WP_046679652	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. DMB20].	52.58	97	46	0	18	114	18	114	1e-30	120
rs:WP_027533864	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. WSM3983].	51.35	111	51	1	19	126	17	127	1e-30	118
rs:WP_035032483	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Proteobacteria].	55.34	103	44	1	17	117	23	125	1e-30	118
rs:WP_022127301	phosphoribosyl-AMP cyclohydrolase [Ruminococcus sp. CAG:579].	55.79	95	42	0	20	114	15	109	1e-30	117
rs:WP_036347413	phosphoribosyl-AMP cyclohydrolase [Microvirga sp. BSC39].	55.24	105	45	1	15	117	21	125	1e-30	118
rs:WP_022100877	phosphoribosyl-AMP cyclohydrolase [Proteobacteria bacterium CAG:139].	55.67	97	42	1	18	113	5	101	1e-30	117
rs:WP_043794574	phosphoribosyl-AMP cyclohydrolase [Arthrobacter chlorophenolicus].	57.45	94	40	0	19	112	27	120	1e-30	118
rs:WP_020012776	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Agrobacterium].	52.14	117	50	2	19	129	24	140	1e-30	118
rs:WP_005001205	phosphoribosyl-AMP cyclohydrolase [Acinetobacter ursingii].	55.67	97	42	1	18	113	10	106	1e-30	121
rs:WP_002304616	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	52.63	95	45	0	22	116	11	105	1e-30	117
rs:WP_012269045	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Thermoanaerobacter].	51.00	100	49	0	14	113	3	102	1e-30	120
rs:WP_044434055	phosphoribosyl-ATP diphosphatase [Acinetobacter ursingii].	55.67	97	42	1	18	113	10	106	1e-30	121
rs:WP_035898711	phosphoribosyl-AMP cyclohydrolase, partial [Leifsonia rubra].	57.89	95	40	0	18	112	8	102	1e-30	117
rs:WP_019314062	phosphoribosyl-AMP cyclohydrolase, partial [Streptococcus mutans].	53.19	94	44	0	21	114	10	103	1e-30	117
rs:WP_002280810	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	52.63	95	45	0	22	116	11	105	1e-30	117
rs:WP_004975893	phosphoribosyl-AMP cyclohydrolase [Acinetobacter towneri].	54.64	97	43	1	18	113	10	106	1e-30	121
rs:WP_024719883	phosphoribosyl-ATP pyrophosphatase [Bacillus pumilus].	53.27	107	47	1	16	122	5	108	1e-30	120
rs:WP_024101212	phosphoribosyl-AMP cyclohydrolase [Rhodococcus pyridinivorans].	54.55	99	45	0	18	116	13	111	1e-30	117
rs:WP_004400582	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Thermoanaerobacter].	51.00	100	49	0	14	113	3	102	1e-30	120
rs:WP_033490003	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium indicum].	55.79	95	42	0	18	112	20	114	1e-30	118
rs:WP_024370244	phosphoribosyl-AMP cyclohydrolase [Exiguobacterium sp. 8-11-1].	50.00	100	50	0	18	117	10	109	1e-30	117
tr:G9PKJ0_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.83	106	50	0	15	120	8	113	1e-30	117
rs:WP_013193550	phosphoribosyl-AMP cyclohydrolase [Methanohalobium evestigatum].	51.92	104	49	1	14	117	3	105	1e-30	117
sp:HIS3_RHISN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.43	117	54	2	17	129	22	138	1e-30	118
sp:HIS3_GEOSL	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.33	105	47	2	17	119	3	107	1e-30	117
rs:WP_018979005	hypothetical protein [Saccharibacillus kuerlensis].	51.85	108	50	1	16	121	16	123	1e-30	121
rs:WP_045554405	phosphoribosyl-AMP cyclohydrolase [Listeria innocua].	49.51	103	51	1	16	118	2	103	1e-30	117
rs:WP_004810048	phosphoribosyl-AMP cyclohydrolase [Acinetobacter schindleri].	52.83	106	48	2	18	121	10	115	1e-30	121
rs:WP_021606178	phosphoribosyl-AMP cyclohydrolase [Actinomyces johnsonii].	52.34	107	51	0	15	121	8	114	1e-30	117
rs:WP_005181811	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Acinetobacter].	52.83	106	48	2	18	121	10	115	1e-30	121
rs:WP_045898120	phosphoribosyl-AMP cyclohydrolase [Clostridium botulinum].	54.26	94	43	0	23	116	16	109	1e-30	117
rs:WP_037555572	phosphoribosyl-AMP cyclohydrolase [Sphingopyxis sp. LC363].	54.55	99	45	0	19	117	14	112	1e-30	117
rs:WP_012863731	phosphoribosyl-AMP cyclohydrolase [Veillonella parvula].	55.32	94	42	0	24	117	10	103	1e-30	117
rs:WP_045796166	phosphoribosyl-ATP diphosphatase [Acinetobacter indicus].	52.83	106	48	2	18	121	10	115	1e-30	121
tr:C9CIA2_ENTCA	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	46.90	113	60	0	18	130	7	119	1e-30	120
sp:HIS3_PELPD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.88	104	47	2	18	119	4	107	1e-30	117
rs:WP_019315894	phosphoribosyl-AMP cyclohydrolase, partial [Streptococcus mutans].	53.19	94	44	0	21	114	8	101	1e-30	117
rs:WP_046174362	phosphoribosyl-ATP pyrophosphatase [Domibacillus indicus].	53.68	95	44	0	18	112	5	99	1e-30	120
rs:WP_034868288	phosphoribosyl-ATP pyrophosphatase [Enterococcus casseliflavus].	46.90	113	60	0	18	130	4	116	1e-30	120
rs:WP_026939831	phosphoribosyl-AMP cyclohydrolase [Humibacter albus].	55.67	97	43	0	18	114	13	109	1e-30	117
tr:A9M2Q4_NEIM0	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.78	108	50	1	25	131	1	108	1e-30	117
rs:WP_003866546	phosphoribosyl-ATP pyrophosphatase [Thermoanaerobacter ethanolicus].	51.00	100	49	0	14	113	3	102	1e-30	120
rs:WP_034588472	phosphoribosyl-ATP diphosphatase [Acinetobacter sp. HR7].	52.83	106	48	2	18	121	10	115	1e-30	121
rs:WP_020811294	phosphoribosyl-AMP cyclohydrolase [Agrobacterium tumefaciens].	52.14	117	50	2	19	129	24	140	1e-30	118
tr:B1Z863_METPB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.21	113	47	2	7	117	19	126	1e-30	118
rs:WP_020864195	phosphoribosyl-AMP cyclohydrolase [Candidatus Caldiarchaeum subterraneum].	52.08	96	46	0	18	113	6	101	1e-30	117
rs:WP_041371308	phosphoribosyl-AMP cyclohydrolase [Methylobacterium populi].	52.21	113	47	2	7	117	16	123	1e-30	118
rs:WP_015115340	phosphoribosyl-AMP cyclohydrolase [Nostoc sp. PCC 7107].	53.54	99	45	1	18	115	18	116	1e-30	120
rs:WP_027506788	phosphoribosyl-AMP cyclohydrolase [Rhodococcus sp. UNC23MFCrub1.1].	55.79	95	42	0	18	112	14	108	1e-30	117
tr:F6ISK9_LACPE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.26	94	43	0	24	117	10	103	1e-30	117
rs:WP_019315337	phosphoribosyl-AMP cyclohydrolase, partial [Streptococcus mutans].	53.19	94	44	0	21	114	10	103	1e-30	117
rs:WP_036386105	phosphoribosyl-AMP cyclohydrolase [Microvirgula aerodenitrificans].	50.00	114	56	1	18	130	10	123	1e-30	117
rs:WP_044457280	phosphoribosyl-AMP cyclohydrolase [Pandoraea vervacti].	50.48	105	51	1	18	121	9	113	1e-30	117
sp:HIS3_RUTMC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	44.25	113	62	1	19	130	8	120	1e-30	117
rs:WP_034683434	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	54.64	97	43	1	18	113	10	106	1e-30	121
rs:WP_018721563	phosphoribosyl-AMP cyclohydrolase [Salinispora pacifica].	54.63	108	46	2	18	122	35	142	1e-30	118
rs:WP_026721371	imidazole glycerol phosphate synthase [Fischerella sp. PCC 9431].	52.53	99	46	1	18	115	18	116	1e-30	120
tr:X1F3R8_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_C00705 {ECO:0000313|EMBL:GAH23994.1};	51.58	95	46	0	24	118	16	110	1e-30	120
rs:WP_007470048	phosphoribosyl-AMP cyclohydrolase [Segniliparus rugosus].	57.89	95	40	0	18	112	16	110	1e-30	117
rs:WP_008538427	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Megamonas].	54.00	100	45	1	13	112	2	100	1e-30	120
rs:WP_007532744	phosphoribosyl-AMP cyclohydrolase [Rhizobium mesoamericanum].	51.26	119	52	3	17	131	23	139	1e-30	118
rs:WP_039169086	phosphoribosyl-ATP pyrophosphatase [Bacillus altitudinis].	53.27	107	47	1	16	122	5	108	1e-30	120
rs:WP_019807973	phosphoribosyl-AMP cyclohydrolase [Saccharomonospora halophila].	54.63	108	44	1	18	125	13	115	1e-30	117
rs:WP_042335391	phosphoribosyl-AMP cyclohydrolase [Candidatus Accumulibacter sp. BA-92].	53.06	98	45	1	17	113	13	110	1e-30	117
rs:WP_045883854	phosphoribosyl-AMP cyclohydrolase [Clostridium botulinum].	55.43	92	41	0	23	114	16	107	1e-30	117
rs:WP_046805263	phosphoribosyl-AMP cyclohydrolase [Achromobacter sp. LC458].	57.66	111	43	2	20	126	13	123	1e-30	117
rs:WP_020255905	hypothetical protein [Candidatus Paceibacter normanii].	50.00	98	49	0	24	121	16	113	1e-30	117
rs:WP_003388239	phosphoribosyl-AMP cyclohydrolase [Brevibacillus borstelensis].	50.98	102	50	0	11	112	3	104	1e-30	121
rs:WP_028297324	phosphoribosyl-ATP pyrophosphatase [Olivibacter sitiensis].	53.54	99	45	1	17	114	2	100	1e-30	119
rs:WP_045452441	phosphoribosyl-AMP cyclohydrolase [Psychrobacter sp. JCM 18903].	55.56	99	43	1	16	113	8	106	1e-30	121
rs:WP_008245573	phosphoribosyl-ATP pyrophosphatase [Sulfurovum sp. AR].	49.54	109	53	1	18	126	3	109	1e-30	120
rs:WP_007500081	bifunctional phosphoribosyl-amp cyclohydrolase phosphoribosyl-ATP pyrophosphatase [Bacillus stratosphericus].	53.27	107	47	1	16	122	5	108	1e-30	119
rs:WP_041833383	phosphoribosyl-AMP cyclohydrolase [Actinoplanes sp. N902-109].	55.79	95	42	0	18	112	34	128	1e-30	118
rs:WP_010163908	phosphoribosyl-AMP cyclohydrolase [Sphingomonas sp. PAMC 26617].	54.90	102	46	0	19	120	14	115	1e-30	117
rs:WP_045312363	phosphoribosyl-AMP cyclohydrolase [Lechevalieria aerocolonigenes].	55.14	107	46	1	15	119	10	116	1e-30	117
rs:WP_045034002	phosphoribosyl-ATP pyrophosphatase [Bacillus invictae].	53.27	107	47	1	16	122	5	108	1e-30	119
rs:WP_003508062	phosphoribosyl-AMP cyclohydrolase [Agrobacterium tumefaciens].	52.14	117	50	2	19	129	24	140	1e-30	118
tr:I0L8Q2_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00006950}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	54.64	97	44	0	18	114	326	422	1e-30	123
rs:WP_039375169	phosphoribosyl-AMP cyclohydrolase [Pandoraea pnomenusa].	51.49	101	48	1	18	117	9	109	1e-30	117
rs:WP_031297545	phosphoribosyl-AMP cyclohydrolase [Sphingobium lactosutens].	55.10	98	44	0	19	116	14	111	1e-30	117
rs:WP_026515857	hypothetical protein [Butyrivibrio sp. MC2021].	53.92	102	47	0	12	113	225	326	1e-30	123
rs:WP_039070233	phosphoribosyl-ATP pyrophosphatase [Brevibacillus borstelensis].	50.98	102	50	0	11	112	3	104	1e-30	120
rs:WP_013147013	phosphoribosyl-AMP cyclohydrolase [Methylotenera versatilis].	46.43	112	59	1	18	128	7	118	1e-30	117
rs:WP_045055578	imidazole glycerol phosphate synthase [Chroococcales cyanobacterium CENA595].	50.00	108	53	1	9	115	8	115	1e-30	120
rs:WP_035005154	phosphoribosyl-AMP cyclohydrolase [Betaproteobacteria bacterium MOLA814].	50.93	108	49	1	18	121	1	108	1e-30	117
rs:WP_013038369	phosphoribosyl-AMP cyclohydrolase [Methanohalophilus mahii].	53.12	96	44	1	18	113	7	101	1e-30	117
rs:WP_035230400	phosphoribosyl-AMP cyclohydrolase [Desulfobulbus sp. Tol-SR].	57.14	91	38	1	24	113	12	102	1e-30	117
rs:WP_017553234	phosphoribosyl-ATP pyrophosphatase [Bacillus coagulans].	48.72	117	51	1	24	131	8	124	1e-30	120
rs:WP_005964592	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [sulfur-oxidizing symbionts].	52.53	99	46	1	16	113	6	104	1e-30	117
rs:WP_026895415	phosphoribosyl-ATP pyrophosphatase [Clostridiisalibacter paucivorans].	49.07	108	54	1	11	118	1	107	1e-30	119
rs:WP_031584694	phosphoribosyl-ATP pyrophosphatase [Selenomonas bovis].	51.96	102	48	1	11	112	1	101	1e-30	120
rs:WP_010589617	histidine biosynthesis bifunctional protein hisIE, partial [Acinetobacter parvus].	53.61	97	44	1	18	113	8	104	1e-30	117
rs:WP_021754757	phosphoribosyl-AMP cyclohydrolase [Leifsonia xyli].	50.96	104	51	0	9	112	2	105	1e-30	117
rs:WP_019542113	phosphoribosyl-ATP pyrophosphatase [Selenomonas bovis].	51.96	102	48	1	11	112	1	101	1e-30	120
rs:WP_018033442	hypothetical protein [crenarchaeote SCGC AAA261-L14].	48.51	101	51	1	14	113	8	108	1e-30	117
rs:WP_043331113	phosphoribosyl-AMP cyclohydrolase [Micromonospora sp. M42].	54.64	97	44	0	18	114	30	126	1e-30	117
rs:WP_033489608	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium pseudolongum].	54.74	95	43	0	18	112	23	117	1e-30	117
rs:WP_021768671	phosphoribosyl-ATP diphosphatase [Leptotrichia sp. oral taxon 225].	50.52	97	48	0	18	114	6	102	1e-30	120
rs:WP_017604485	phosphoribosyl-AMP cyclohydrolase [Nocardiopsis alkaliphila].	54.74	95	43	0	18	112	14	108	1e-30	117
rs:WP_044974037	phosphoribosyl-AMP cyclohydrolase [Ruminococcus sp. HUN007].	54.74	95	43	0	20	114	13	107	1e-30	117
rs:WP_019175100	hypothetical protein [Brevibacterium massiliense].	52.63	95	45	0	18	112	10	104	1e-30	117
rs:WP_022293217	imidazole glycerol phosphate synthase subunit HisF [Eubacterium rectale CAG:36].	52.94	102	48	0	12	113	223	324	1e-30	123
rs:WP_028991353	phosphoribosyl-ATP pyrophosphatase [Thermoanaerobacter thermocopriae].	51.00	100	49	0	14	113	3	102	1e-30	120
rs:WP_036275343	phosphoribosyl-AMP cyclohydrolase [Methylomonas denitrificans].	45.61	114	61	1	18	130	9	122	1e-30	117
rs:WP_044983192	hypothetical protein [Ruminococcus gauvreauii].	57.14	98	42	0	16	113	217	314	1e-30	123
rs:WP_025695837	phosphoribosyl-ATP pyrophosphatase [Paenibacillus durus].	55.21	96	43	0	18	113	19	114	1e-30	120
rs:WP_047334572	phosphoribosyl-ATP pyrophosphatase [Enterococcus cecorum].	47.41	116	59	1	13	126	2	117	1e-30	119
rs:WP_037449434	phosphoribosyl-AMP cyclohydrolase [Sinorhizobium fredii].	50.43	117	54	2	17	129	22	138	1e-30	118
rs:WP_026760764	phosphoribosyl-ATP pyrophosphatase [Selenomonas ruminantium].	47.41	116	58	2	12	125	3	117	2e-30	120
rs:WP_047341353	phosphoribosyl-ATP pyrophosphatase [Enterococcus cecorum].	47.41	116	59	1	13	126	2	117	2e-30	119
rs:WP_004978775	phosphoribosyl-AMP cyclohydrolase [Acinetobacter johnsonii].	52.83	106	48	2	18	121	10	115	2e-30	120
tr:A0A0C6FCQ8_9RHIZ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	56.86	102	42	1	17	116	23	124	2e-30	117
sp:HIS2_PHOPR	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	48.11	106	55	0	24	129	14	119	2e-30	119
sp:HIS3_RHOP5	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.00	100	46	1	19	117	23	122	2e-30	117
tr:A0A098EDC0_9ZZZZ	SubName: Full=Bifunctional protein {ECO:0000313|EMBL:CEG13506.1}; EC=3.5.4.19 {ECO:0000313|EMBL:CEG13506.1}; EC=3.6.1.31 {ECO:0000313|EMBL:CEG13506.1};	50.51	99	49	0	19	117	20	118	2e-30	117
rs:WP_005405963	phosphoribosyl-ATP diphosphatase [Acinetobacter radioresistens].	53.61	97	44	1	18	113	10	106	2e-30	120
tr:E0MYT0_9CORY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	56.84	95	40	1	18	112	17	110	2e-30	117
rs:WP_034254840	phosphoribosyl-AMP cyclohydrolase [Actinomyces sp. oral taxon 448].	52.83	106	50	0	15	120	6	111	2e-30	117
rs:WP_025651517	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Psychrobacter].	54.55	99	44	1	16	113	8	106	2e-30	121
rs:WP_045539745	phosphoribosyl-AMP cyclohydrolase [Clostridium botulinum].	55.43	92	41	0	23	114	16	107	2e-30	116
rs:WP_027173116	phosphoribosyl-AMP cyclohydrolase [Methylobacterium sp. 10].	56.73	104	43	1	15	116	25	128	2e-30	117
rs:WP_005023355	phosphoribosyl-ATP pyrophosphatase [Helicobacter pullorum].	52.69	93	44	0	22	114	13	105	2e-30	120
rs:WP_027022551	phosphoribosyl-AMP cyclohydrolase [Conchiformibius steedae].	49.56	113	56	1	17	128	9	121	2e-30	117
tr:A0A098E847_9ZZZZ	SubName: Full=Bifunctional protein {ECO:0000313|EMBL:CEG12182.1}; EC=3.5.4.19 {ECO:0000313|EMBL:CEG12182.1}; EC=3.6.1.31 {ECO:0000313|EMBL:CEG12182.1};	51.52	99	48	0	19	117	20	118	2e-30	117
rs:WP_005016950	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Acinetobacter].	53.61	97	44	1	18	113	10	106	2e-30	120
rs:WP_006336082	phosphoribosyl-AMP cyclohydrolase [Gordonia rhizosphera].	53.70	108	47	1	18	122	11	118	2e-30	117
rs:WP_027277558	phosphoribosyl-AMP cyclohydrolase [Rhodopseudomonas palustris].	51.79	112	47	3	7	117	12	117	2e-30	117
rs:WP_022885120	phosphoribosyl-AMP cyclohydrolase [Glaciibacter superstes].	58.06	93	39	0	20	112	12	104	2e-30	117
rs:WP_026683473	imidazole glycerol phosphate synthase [Bacillus coagulans].	50.00	104	52	0	24	127	8	111	2e-30	120
tr:H6QZ45_NOCCG	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.74	95	43	0	18	112	11	105	2e-30	117
sp:HIS3_GEOBB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	51.52	99	47	1	23	120	10	108	2e-30	117
rs:WP_026551785	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. H20].	50.47	107	52	1	7	112	15	121	2e-30	117
rs:WP_004991624	phosphoribosyl-ATP diphosphatase [Acinetobacter ursingii].	55.67	97	42	1	18	113	10	106	2e-30	120
rs:WP_012992549	phosphoribosyl-ATP pyrophosphatase [Thermocrinis albus].	50.00	106	51	2	17	121	10	114	2e-30	119
rs:WP_025426725	phosphoribosyl-AMP cyclohydrolase [Ensifer adhaerens].	50.00	116	56	1	17	130	22	137	2e-30	117
rs:WP_016168384	phosphoribosyl-AMP cyclohydrolase [Acinetobacter tandoii].	54.64	97	43	1	18	113	10	106	2e-30	120
rs:WP_004021168	phosphoribosyl-AMP cyclohydrolase [Gordonia terrae].	54.72	106	47	1	10	114	2	107	2e-30	117
rs:WP_015256268	phosphoribosyl-ATP pyrophosphatase [Thermobacillus composti].	50.93	108	51	2	17	122	7	114	2e-30	119
sp:HIS3_RHILO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.43	117	46	2	19	123	25	141	2e-30	118
rs:WP_035532441	phosphoribosyl-AMP cyclohydrolase [Hoeflea sp. BAL378].	50.89	112	51	2	19	126	24	135	2e-30	117
rs:WP_004800264	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. CIP 102637].	54.64	97	43	1	18	113	8	104	2e-30	120
rs:WP_005189266	phosphoribosyl-AMP cyclohydrolase [Gordonia amarae].	55.66	106	46	1	10	114	2	107	2e-30	117
rs:WP_003760704	phosphoribosyl-AMP cyclohydrolase [Listeria innocua].	49.51	103	51	1	16	118	2	103	2e-30	116
rs:WP_043616499	phosphoribosyl-AMP cyclohydrolase [Ensifer sp. ZNC0028].	52.10	119	51	3	17	129	22	140	2e-30	117
tr:U5QL76_9CYAN	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	57.29	96	40	1	19	113	9	104	2e-30	119
rs:WP_044740589	phosphoribosyl-ATP diphosphatase [Bacillus mycoides].	54.64	97	43	1	18	113	10	106	2e-30	120
rs:WP_006915147	phosphoribosyl-AMP cyclohydrolase [Salinisphaera shabanensis].	50.49	103	50	1	18	119	22	124	2e-30	117
rs:WP_017750722	hypothetical protein [Clostridium tyrobutyricum].	51.61	93	45	0	22	114	17	109	2e-30	116
rs:WP_037178377	phosphoribosyl-AMP cyclohydrolase [Rhizobium sp. YR519].	50.42	119	53	3	17	131	22	138	2e-30	117
rs:WP_014098406	phosphoribosyl-ATP pyrophosphatase [Bacillus coagulans].	50.00	104	52	0	24	127	8	111	2e-30	119
rs:WP_029019871	phosphoribosyl-AMP cyclohydrolase [Salinispora arenicola].	52.53	99	47	0	16	114	33	131	2e-30	117
rs:WP_036834694	phosphoribosyl-ATP pyrophosphatase [Pontibacillus litoralis].	51.58	95	46	0	18	112	6	100	2e-30	119
rs:WP_002267427	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	52.63	95	45	0	22	116	11	105	2e-30	116
rs:WP_006959674	phosphoribosyl-AMP cyclohydrolase [Sphingobium japonicum].	53.92	102	47	0	15	116	10	111	2e-30	117
rs:WP_019137289	phosphoribosyl-AMP cyclohydrolase [Cellulomonas massiliensis].	55.79	95	42	0	18	112	15	109	2e-30	117
rs:WP_005094361	phosphoribosyl-AMP cyclohydrolase [Acinetobacter lwoffii].	52.83	106	48	2	18	121	10	115	2e-30	120
rs:WP_010325778	phosphoribosyl-ATP diphosphatase [Acinetobacter lwoffii].	52.83	106	48	2	18	121	10	115	2e-30	120
rs:WP_004692689	phosphoribosyl-AMP cyclohydrolase [Acinetobacter johnsonii].	52.83	106	48	2	18	121	10	115	2e-30	120
rs:WP_041348664	phosphoribosyl-AMP cyclohydrolase [Clostridium botulinum].	54.35	92	42	0	23	114	16	107	2e-30	116
rs:WP_040594837	phosphoribosyl-AMP cyclohydrolase, partial [Timonella senegalensis].	55.67	97	43	0	18	114	9	105	2e-30	116
rs:WP_005051045	phosphoribosyl-AMP cyclohydrolase [Acinetobacter beijerinckii].	54.64	97	43	1	18	113	8	104	2e-30	120
rs:WP_029026559	phosphoribosyl-AMP cyclohydrolase [Salinispora arenicola].	52.53	99	47	0	16	114	33	131	2e-30	117
rs:WP_018325106	hypothetical protein [Rhizobium giardinii].	50.43	117	56	1	17	131	22	138	2e-30	117
rs:WP_006899568	phosphoribosyl-AMP cyclohydrolase [Gordonia paraffinivorans].	56.70	97	42	0	18	114	11	107	2e-30	117
rs:WP_034834023	phosphoribosyl-AMP cyclohydrolase, partial [Endozoicomonas numazuensis].	50.91	110	53	1	18	126	7	116	2e-30	117
rs:WP_025025565	phosphoribosyl-ATP pyrophosphatase [Bacillus mannanilyticus].	51.85	108	48	1	18	121	8	115	2e-30	119
rs:WP_026175979	phosphoribosyl-AMP cyclohydrolase [Methylobacterium sp. 88A].	56.73	104	43	1	15	116	13	116	2e-30	117
rs:WP_026487789	hypothetical protein [Butyrivibrio sp. XBB1001].	53.47	101	47	0	13	113	228	328	2e-30	123
rs:WP_014927247	phosphoribosyl-AMP cyclohydrolase [Gordonia sp. KTR9].	54.72	106	47	1	10	114	2	107	2e-30	117
rs:WP_046648006	phosphoribosyl-AMP cyclohydrolase [Corynebacterium minutissimum].	60.00	95	37	1	18	112	27	120	2e-30	117
rs:WP_005168926	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. NIPH 713].	52.83	106	48	2	18	121	10	115	2e-30	120
rs:WP_039885731	phosphoribosyl-AMP cyclohydrolase [Corynebacterium accolens].	56.84	95	40	1	18	112	22	115	2e-30	117
rs:WP_034309952	phosphoribosyl-ATP pyrophosphatase [Bacillus simplex].	47.66	107	55	1	14	119	2	108	2e-30	119
sp:HIS3_METFK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	54.74	95	42	1	24	117	15	109	2e-30	117
rs:WP_029763534	phosphoribosyl-ATP pyrophosphatase, partial [Gemmatimonadetes bacterium JGI 0000112-M07].	51.92	104	50	0	18	121	15	118	2e-30	120
tr:B8H6U4_ARTCA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.45	94	40	0	19	112	70	163	2e-30	118
rs:WP_017823609	phosphoribosyl-AMP cyclohydrolase [Brachybacterium muris].	55.77	104	41	1	18	121	21	119	2e-30	117
rs:WP_006656365	phosphoribosyl-ATP pyrophosphatase [Helicobacter canadensis].	50.48	105	45	1	22	126	13	110	2e-30	120
tr:R4LK14_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	55.79	95	42	0	18	112	40	134	2e-30	117
rs:WP_021914910	hypothetical protein [Firmicutes bacterium CAG:24].	49.15	118	58	1	5	122	218	333	2e-30	123
rs:WP_041244947	imidazole glycerol phosphate synthase [Gloeobacter kilaueensis].	57.29	96	40	1	19	113	18	113	2e-30	119
rs:WP_019743394	phosphoribosyl-ATP pyrophosphatase [Bacillus pumilus].	55.67	97	43	0	16	112	5	101	2e-30	119
rs:WP_016697347	phosphoribosyl-AMP cyclohydrolase [Actinoalloteichus spitiensis].	57.89	95	40	0	18	112	14	108	2e-30	117
tr:A0A011UXX9_RUMAL	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.26	94	43	0	20	113	8	101	2e-30	116
rs:WP_020151192	hypothetical protein [Verrucomicrobia bacterium SCGC AAA164-M04].	51.30	115	54	2	19	131	24	138	2e-30	117
rs:WP_024092994	histidine biosynthesis bifunctional protein HisIE [Paenibacillus larvae].	52.04	98	47	0	15	112	10	107	2e-30	120
rs:WP_002281159	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	52.08	96	46	0	21	116	10	105	2e-30	116
rs:WP_019111805	MULTISPECIES: hypothetical protein [unclassified Verrucomicrobia (miscellaneous)].	51.30	115	54	2	19	131	24	138	2e-30	117
rs:WP_036129783	phosphoribosyl-AMP cyclohydrolase [Listeriaceae bacterium FSL A5-0209].	51.89	106	50	1	17	122	2	106	2e-30	116
rs:WP_021918747	phosphoribosyl-AMP cyclohydrolase [Firmicutes bacterium CAG:114].	46.79	109	58	0	13	121	2	110	2e-30	119
rs:WP_002282464	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	52.63	95	45	0	22	116	11	105	2e-30	116
rs:WP_009676836	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Paenibacillus].	53.12	96	45	0	17	112	8	103	2e-30	119
rs:WP_010306870	phosphoribosyl-ATP pyrophosphatase [Kurthia sp. JC8E].	48.67	113	57	1	17	128	2	114	2e-30	119
rs:WP_038491280	phosphoribosyl-AMP cyclohydrolase [Agrobacterium tumefaciens].	52.14	117	50	2	19	129	24	140	2e-30	117
rs:WP_019228839	hypothetical protein [Sedimentibacter sp. B4].	54.46	101	46	0	16	116	6	106	2e-30	119
rs:WP_025871650	phosphoribosyl-AMP cyclohydrolase [Methylobacillus glycogenes].	49.51	103	51	1	18	119	7	109	2e-30	117
rs:WP_041091647	phosphoribosyl-ATP pyrophosphatase [Bacillus pumilus].	53.27	107	47	1	16	122	5	108	2e-30	119
rs:WP_024774338	phosphoribosyl-ATP diphosphatase [Arcobacter cibarius].	51.06	94	46	0	24	117	14	107	2e-30	119
rs:WP_031269315	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Labrenzia].	51.82	110	48	2	19	123	24	133	2e-30	117
rs:WP_012695682	phosphoribosyl-AMP cyclohydrolase [Laribacter hongkongensis].	48.25	114	58	1	18	130	13	126	2e-30	117
tr:S3X050_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	50.43	117	55	1	11	124	1	117	2e-30	117
rs:WP_027469813	phosphoribosyl-AMP cyclohydrolase [Deefgea rivuli].	46.49	114	60	1	18	130	10	123	2e-30	117
rs:WP_008348143	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillus].	56.84	95	41	0	18	112	7	101	2e-30	119
tr:A0A087C8U4_9BIFI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.74	95	43	0	18	112	32	126	2e-30	117
rs:WP_005263919	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Acinetobacter].	52.83	106	48	2	18	121	10	115	2e-30	120
rs:WP_037352026	phosphoribosyl-ATP pyrophosphatase [Selenomonas sp. FC4001].	47.41	116	58	2	12	125	3	117	2e-30	120
tr:X1ABU1_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_C04376 {ECO:0000313|EMBL:GAG70158.1}; Flags: Fragment;	51.58	95	46	0	24	118	16	110	2e-30	116
rs:WP_041141273	phosphoribosyl-ATP diphosphatase [Sulfurovum sp. PC08-66].	49.56	113	55	1	18	128	7	119	2e-30	119
rs:WP_004281119	phosphoribosyl-ATP diphosphatase [Acinetobacter lwoffii].	51.85	108	50	2	18	123	10	117	2e-30	120
tr:A0A098F6C6_9BACI	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	47.66	107	55	1	14	119	2	108	2e-30	119
rs:WP_013636306	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Agrobacterium].	52.14	117	50	2	19	129	24	140	2e-30	117
rs:WP_013414254	phosphoribosyl-AMP cyclohydrolase [Methanothermus fervidus].	51.55	97	47	0	21	117	8	104	2e-30	117
rs:WP_037280055	phosphoribosyl-AMP cyclohydrolase [Ruminococcus flavefaciens].	55.32	94	42	0	20	113	13	106	2e-30	116
rs:WP_044466633	phosphoribosyl-ATP pyrophosphatase [Staphylococcus caprae].	52.69	93	44	0	24	116	10	102	2e-30	119
rs:WP_025208029	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillus].	55.67	97	43	0	16	112	5	101	2e-30	119
tr:G0HAF7_CORVD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	57.47	87	37	0	26	112	1	87	2e-30	115
tr:K2FMT2_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	51.85	108	50	2	18	123	10	117	2e-30	120
rs:WP_031434289	phosphoribosyl-AMP cyclohydrolase [Methylomarinum vadi].	44.35	124	64	2	8	130	3	122	2e-30	117
rs:WP_006936575	phosphoribosyl-AMP cyclohydrolase [Labrenzia aggregata].	49.17	120	53	3	19	130	24	143	2e-30	117
rs:WP_004039564	phosphoribosyl-AMP cyclohydrolase [Methanofollis liminatans].	54.64	97	44	0	23	119	7	103	2e-30	116
rs:WP_008336284	phosphoribosyl-ATP pyrophosphatase [Sulfurimonas gotlandica].	50.00	106	53	0	25	130	15	120	2e-30	119
rs:WP_005445924	phosphoribosyl-AMP cyclohydrolase [Saccharomonospora azurea].	52.78	108	46	1	18	125	12	114	2e-30	116
rs:WP_025209220	phosphoribosyl-ATP pyrophosphatase [Hippea sp. KM1].	46.55	116	62	0	15	130	4	119	2e-30	120
rs:WP_045772100	phosphoribosyl-AMP cyclohydrolase [Streptococcus salivarius].	50.00	108	48	1	11	118	6	107	2e-30	116
rs:WP_010808183	phosphoribosyl-AMP cyclohydrolase [Pandoraea sp. SD6-2].	50.50	101	49	1	18	117	9	109	2e-30	117
rs:WP_019312868	phosphoribosyl-AMP cyclohydrolase, partial [Streptococcus mutans].	53.19	94	44	0	21	114	10	103	2e-30	116
tr:D4KXE4_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	50.00	108	52	1	25	130	1	108	2e-30	119
rs:WP_034942924	phosphoribosyl-AMP cyclohydrolase [Candidatus Accumulibacter sp. SK-12].	50.00	110	48	2	11	119	4	107	2e-30	117
rs:WP_006231150	phosphoribosyl-AMP cyclohydrolase [Photobacterium profundum].	48.11	106	55	0	24	129	14	119	2e-30	119
rs:WP_042232322	phosphoribosyl-ATP pyrophosphatase [Paenibacillus chitinolyticus].	54.17	96	44	0	17	112	8	103	2e-30	119
rs:WP_025394657	phosphoribosyl-AMP cyclohydrolase [Rhizobium leguminosarum].	50.43	117	56	1	17	131	23	139	2e-30	117
rs:WP_028721469	phosphoribosyl-ATP diphosphatase [Patulibacter americanus].	51.49	101	49	0	15	115	2	102	2e-30	119
rs:WP_024784438	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	53.19	94	44	0	21	114	10	103	2e-30	116
rs:WP_004732472	phosphoribosyl-AMP cyclohydrolase [Acinetobacter lwoffii].	54.64	97	43	1	18	113	10	106	2e-30	120
rs:WP_005627494	phosphoribosyl-AMP cyclohydrolase [Mycobacterium hassiacum].	55.79	95	42	0	18	112	11	105	2e-30	116
rs:WP_036065837	phosphoribosyl-AMP cyclohydrolase [Listeria grandensis].	54.55	99	44	1	17	115	2	99	2e-30	116
rs:WP_017974208	hypothetical protein [Actinopolyspora halophila].	55.79	95	42	0	18	112	19	113	2e-30	116
rs:WP_027405034	phosphoribosyl-AMP cyclohydrolase [Aquaspirillum serpens].	46.49	114	60	1	18	130	8	121	2e-30	117
rs:WP_030530899	phosphoribosyl-AMP cyclohydrolase [Prauserella rugosa].	53.85	104	46	1	18	119	10	113	2e-30	116
rs:WP_034901897	phosphoribosyl-AMP cyclohydrolase [Erythrobacter litoralis].	52.13	94	45	0	20	113	16	109	2e-30	117
rs:WP_024856421	phosphoribosyl-AMP cyclohydrolase [Ruminococcus albus].	54.26	94	43	0	20	113	15	108	2e-30	116
tr:X1L406_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S29414 {ECO:0000313|EMBL:GAH97164.1}; Flags: Fragment;	52.58	97	46	0	17	113	19	115	2e-30	117
rs:WP_042203050	imidazole glycerol phosphate synthase [Nodularia spumigena].	53.54	99	45	1	18	115	18	116	2e-30	119
rs:WP_014793312	phosphoribosyl-ATP pyrophosphatase [Desulfitobacterium dehalogenans].	50.93	108	52	1	18	125	17	123	2e-30	119
rs:WP_017836067	phosphoribosyl-AMP cyclohydrolase [Dietzia sp. UCD-THP].	59.34	91	37	0	24	114	20	110	2e-30	116
rs:WP_004644932	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Acinetobacter].	51.85	108	50	2	18	123	10	117	2e-30	120
rs:WP_039945411	phosphoribosyl-ATP pyrophosphatase [Thermicanus aegyptius].	48.72	117	59	1	13	128	1	117	2e-30	119
rs:WP_009469659	phosphoribosyl-AMP cyclohydrolase [Roseibium sp. TrichSKD4].	50.00	114	56	1	19	131	25	138	2e-30	117
tr:Z9JYG1_9MICO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	56.84	95	41	0	18	112	9	103	2e-30	116
rs:WP_033437811	phosphoribosyl-AMP cyclohydrolase [Saccharothrix sp. NRRL B-16314].	54.13	109	49	1	9	116	3	111	2e-30	116
rs:WP_025300291	phosphoribosyl-AMP cyclohydrolase [Candidatus Endolissoclinum faulkneri].	46.40	125	65	2	4	126	6	130	2e-30	117
rs:WP_005249708	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. CIP 102136].	54.64	97	43	1	18	113	10	106	2e-30	120
rs:WP_022778560	imidazole glycerol phosphate synthase [Butyrivibrio sp. AE3009].	50.47	107	53	0	12	118	224	330	2e-30	122
rs:WP_013682553	phosphoribosyl-ATP pyrophosphatase [Hippea maritima].	47.41	116	61	0	15	130	4	119	2e-30	119
rs:WP_007931805	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Pelosinus].	53.00	100	47	0	13	112	2	101	2e-30	119
rs:WP_037290226	phosphoribosyl-AMP cyclohydrolase [Ruminococcus albus].	54.26	94	43	0	20	113	15	108	2e-30	116
rs:WP_035264019	phosphoribosyl-ATP diphosphatase [Acinetobacter sp. Ver3].	54.64	97	43	1	18	113	10	106	2e-30	120
rs:WP_008190493	phosphoribosyl-ATP pyrophosphatase [Moorea producens].	53.54	99	45	1	18	115	18	116	2e-30	119
rs:WP_031955885	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Acinetobacter calcoaceticus/baumannii complex].	55.67	97	42	1	18	113	10	106	2e-30	120
rs:WP_041756484	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. ORS 278].	49.09	110	53	1	19	125	17	126	2e-30	117
rs:WP_003654602	phosphoribosyl-ATP diphosphatase [Acinetobacter calcoaceticus].	54.64	97	43	1	18	113	10	106	3e-30	120
tr:A0ZMC3_NODSP	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	53.54	99	45	1	18	115	27	125	3e-30	119
rs:WP_002883995	phosphoribosyl-AMP cyclohydrolase [Streptococcus salivarius].	50.00	108	48	1	11	118	6	107	3e-30	116
rs:WP_034616256	phosphoribosyl-ATP pyrophosphatase [Desulfosporosinus sp. Tol-M].	45.54	112	61	0	13	124	4	115	3e-30	119
rs:WP_018789358	phosphoribosyl-AMP cyclohydrolase [Salinispora arenicola].	53.61	97	45	0	18	114	35	131	3e-30	117
rs:WP_019318864	phosphoribosyl-AMP cyclohydrolase, partial [Streptococcus mutans].	52.13	94	45	0	21	114	10	103	3e-30	116
rs:WP_022556294	phosphoribosyl-AMP cyclohydrolase [Rhizobium sp. H41].	53.85	117	48	3	19	129	24	140	3e-30	117
rs:WP_024498856	phosphoribosyl-AMP cyclohydrolase [Gordonia amicalis].	55.67	97	43	0	18	114	11	107	3e-30	116
rs:WP_038370288	phosphoribosyl-AMP cyclohydrolase [Brachybacterium phenoliresistens].	56.84	95	41	0	18	112	14	108	3e-30	116
rs:WP_005108498	phosphoribosyl-AMP cyclohydrolase [Acinetobacter lwoffii].	51.85	108	50	2	18	123	10	117	3e-30	120
tr:D1C4Y5_SPHTD	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	48.25	114	53	2	2	112	1	111	3e-30	119
tr:U7G7P9_9RHOB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	51.82	110	48	2	19	123	35	144	3e-30	117
rs:WP_002265325	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	51.58	95	46	0	22	116	11	105	3e-30	116
rs:WP_015787108	phosphoribosyl-AMP cyclohydrolase [Saccharomonospora viridis].	52.78	108	46	1	18	125	12	114	3e-30	116
rs:WP_039707372	phosphoribosyl-AMP cyclohydrolase [marine actinobacterium MedAcidi-G1].	51.92	104	49	1	12	114	13	116	3e-30	116
sp:HIS3_BRASO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	51.46	103	50	0	19	121	6	108	3e-30	116
rs:WP_018807911	phosphoribosyl-AMP cyclohydrolase [Salinispora arenicola].	53.61	97	45	0	18	114	35	131	3e-30	117
tr:A0A0C2VEF8_9BACL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	46.08	102	55	0	11	112	1	102	3e-30	119
rs:WP_028520345	phosphoribosyl-AMP cyclohydrolase [Ruminococcus flavefaciens].	55.32	94	42	0	20	113	13	106	3e-30	116
rs:WP_044108998	phosphoribosyl-ATP diphosphatase [Acinetobacter sp. MII].	52.83	106	48	2	18	121	10	115	3e-30	120
rs:WP_002275647	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	51.58	95	46	0	22	116	11	105	3e-30	116
rs:WP_002265592	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	53.76	93	43	0	24	116	13	105	3e-30	116
tr:V4YNY1_9PROT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	50.93	108	49	1	18	121	29	136	3e-30	117
rs:WP_010684947	phosphoribosyl-AMP cyclohydrolase [Methylobacterium mesophilicum].	49.18	122	52	3	7	123	19	135	3e-30	117
tr:F9EGG6_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.83	106	50	0	15	120	19	124	3e-30	117
rs:WP_022903086	phosphoribosyl-AMP cyclohydrolase [Curtobacterium sp. B8].	53.68	95	44	0	18	112	16	110	3e-30	116
rs:WP_024298061	phosphoribosyl-AMP cyclohydrolase [Methylosarcina lacus].	46.49	114	60	1	18	130	9	122	3e-30	116
rs:WP_012183495	phosphoribosyl-AMP cyclohydrolase [Salinispora arenicola].	53.61	97	45	0	18	114	35	131	3e-30	117
rs:WP_014634297	phosphoribosyl-AMP cyclohydrolase [Streptococcus salivarius].	50.00	108	48	1	11	118	6	107	3e-30	116
rs:WP_010746658	phosphoribosyl-ATP diphosphatase [Enterococcus raffinosus].	47.83	115	59	1	16	129	2	116	3e-30	119
rs:WP_007474690	phosphoribosyl-ATP pyrophosphatase [Caminibacter mediatlanticus].	52.17	92	44	0	23	114	8	99	3e-30	119
rs:WP_002268278	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	50.52	97	48	0	22	118	11	107	3e-30	116
rs:WP_005400930	phosphoribosyl-ATP diphosphatase [Acinetobacter johnsonii].	52.83	106	48	2	18	121	10	115	3e-30	120
rs:WP_022747237	phosphoribosyl-AMP cyclohydrolase [Clostridium saccharobutylicum].	54.44	90	41	0	24	113	17	106	3e-30	116
tr:G5F111_9ACTN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	48.57	105	54	0	12	116	17	121	3e-30	117
rs:WP_013191568	phosphoribosyl-ATP pyrophosphatase [Trichormus azollae].	53.54	99	45	1	18	115	18	116	3e-30	119
rs:WP_004182677	phosphoribosyl-AMP cyclohydrolase [Streptococcus salivarius].	50.00	108	48	1	11	118	6	107	3e-30	116
rs:WP_013221886	phosphoribosyl-AMP cyclohydrolase [Nitrosococcus watsonii].	52.53	99	46	1	20	117	11	109	3e-30	116
rs:WP_013255444	phosphoribosyl-AMP cyclohydrolase [Spirochaeta smaragdinae].	50.00	104	46	1	10	113	22	119	3e-30	116
rs:WP_039701813	phosphoribosyl-AMP cyclohydrolase [marine actinobacterium MedAcidi-G2B].	51.46	103	49	1	18	119	12	114	3e-30	116
rs:WP_018888147	phosphoribosyl-ATP pyrophosphatase [Paenibacillus massiliensis].	53.12	96	45	0	17	112	18	113	3e-30	119
tr:H0E1U4_9ACTN	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	53.06	98	46	0	15	112	8	105	3e-30	119
rs:WP_002307264	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	51.58	95	46	0	22	116	11	105	3e-30	116
tr:X1SDV5_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_C05266 {ECO:0000313|EMBL:GAI77326.1}; Flags: Fragment;	54.08	98	45	0	16	113	6	103	3e-30	116
rs:WP_039502000	phosphoribosyl-AMP cyclohydrolase [Prauserella sp. Am3].	53.85	104	46	1	18	119	10	113	3e-30	116
rs:WP_018800316	phosphoribosyl-AMP cyclohydrolase [Salinispora arenicola].	53.61	97	45	0	18	114	35	131	3e-30	117
rs:WP_022243843	imidazole glycerol phosphate synthase subunit HisF [Roseburia sp. CAG:45].	47.01	117	60	1	16	130	226	342	3e-30	122
rs:WP_013770956	phosphoribosyl-AMP cyclohydrolase [Cellulomonas fimi].	55.79	95	42	0	18	112	21	115	3e-30	117
rs:WP_036358672	phosphoribosyl-AMP cyclohydrolase [Microvirga lupini].	51.79	112	50	2	19	126	23	134	3e-30	116
rs:WP_024781963	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	51.58	95	46	0	22	116	11	105	3e-30	116
rs:WP_018394562	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillus].	52.63	95	45	0	18	112	5	99	3e-30	119
rs:WP_026746274	phosphoribosyl-ATP pyrophosphatase [Leptotrichia hofstadii].	50.52	97	48	0	18	114	6	102	3e-30	119
rs:WP_034615017	phosphoribosyl-ATP diphosphatase [Acinetobacter sp. ETR1].	54.64	97	43	1	18	113	10	106	3e-30	120
rs:WP_045367688	phosphoribosyl-AMP cyclohydrolase [Methyloceanibacter caenitepidi].	51.85	108	50	1	14	119	20	127	3e-30	117
rs:WP_036630462	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. A9].	51.96	102	49	0	15	116	12	113	3e-30	119
rs:WP_018804509	phosphoribosyl-AMP cyclohydrolase [Salinispora arenicola].	53.61	97	45	0	18	114	35	131	3e-30	117
tr:E3YMN1_9LIST	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	51.58	95	46	0	24	118	9	103	3e-30	115
sp:HIS3_STRMU	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.69	93	44	0	22	114	11	103	3e-30	115
rs:WP_027984114	phosphoribosyl-AMP cyclohydrolase, partial [delta proteobacterium PSCGC 5296].	57.14	91	38	1	24	113	12	102	3e-30	115
rs:WP_043355359	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Methylobacterium].	51.79	112	47	2	7	116	19	125	3e-30	117
rs:WP_037483286	phosphoribosyl-AMP cyclohydrolase [Sphingomonas paucimobilis].	51.89	106	51	0	15	120	10	115	3e-30	116
rs:WP_037481936	phosphoribosyl-AMP cyclohydrolase [Sphaerotilus natans].	53.19	94	40	1	24	113	13	106	3e-30	116
rs:WP_008534361	phosphoribosyl-AMP cyclohydrolase [Streptococcus sp. C150].	50.00	108	48	1	11	118	6	107	3e-30	116
rs:WP_004725466	phosphoribosyl-ATP diphosphatase [Acinetobacter guillouiae].	54.64	97	43	1	18	113	10	106	3e-30	120
rs:WP_031561426	phosphoribosyl-AMP cyclohydrolase [Ruminococcus flavefaciens].	51.96	102	49	0	20	121	13	114	3e-30	116
rs:WP_018582983	phosphoribosyl-AMP cyclohydrolase [Salinispora arenicola].	53.61	97	45	0	18	114	35	131	3e-30	117
rs:WP_004816700	phosphoribosyl-ATP diphosphatase [Acinetobacter guillouiae].	54.64	97	43	1	18	113	10	106	3e-30	120
rs:WP_039671938	phosphoribosyl-ATP diphosphatase [Sulfurospirillum sp. MES].	54.46	101	46	0	17	117	8	108	3e-30	119
rs:WP_005403584	phosphoribosyl-ATP diphosphatase [Acinetobacter junii].	53.61	97	44	1	18	113	8	104	3e-30	120
rs:WP_002285965	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	51.58	95	46	0	22	116	11	105	3e-30	116
rs:WP_005440189	phosphoribosyl-AMP cyclohydrolase [Saccharomonospora azurea].	52.78	108	46	1	18	125	12	114	3e-30	116
rs:WP_042212404	phosphoribosyl-AMP cyclohydrolase [Lysinimicrobium mangrovi].	55.67	97	43	0	16	112	9	105	3e-30	116
rs:WP_017669766	hypothetical protein [Blastomonas sp. AAP53].	55.14	107	46	2	19	123	14	120	3e-30	116
rs:WP_005375309	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Veillonella].	54.55	99	44	1	20	117	5	103	3e-30	115
tr:A0A077L4Q8_ACIGI	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	54.64	97	43	1	18	113	10	106	3e-30	120
rs:WP_011565075	phosphoribosyl-ATP pyrophosphatase [Rubrobacter xylanophilus].	51.89	106	50	1	15	119	4	109	3e-30	119
rs:WP_013498753	phosphoribosyl-AMP cyclohydrolase [Ruminococcus albus].	55.32	94	42	0	20	113	15	108	3e-30	116
rs:WP_026609619	phosphoribosyl-AMP cyclohydrolase [Methylocaldum szegediense].	49.02	102	51	1	18	118	9	110	3e-30	116
rs:WP_043565243	phosphoribosyl-AMP cyclohydrolase [Candidatus Accumulibacter sp. BA-93].	53.06	98	45	1	17	113	13	110	3e-30	116
rs:WP_015721879	phosphoribosyl-AMP cyclohydrolase [Geobacter sp. M18].	51.02	98	47	1	23	119	10	107	3e-30	116
rs:WP_040367235	phosphoribosyl-AMP cyclohydrolase [Brachybacterium paraconglomeratum].	56.84	95	41	0	18	112	9	103	3e-30	116
tr:A0A0C1NP32_9PSEU	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	53.85	104	46	1	18	119	23	126	3e-30	116
rs:WP_027046895	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium loti].	50.43	117	46	2	19	123	25	141	3e-30	117
rs:WP_009169556	phosphoribosyl-AMP cyclohydrolase [Clostridium sp. DL-VIII].	57.78	90	38	0	24	113	17	106	3e-30	115
rs:WP_044355362	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. E194].	50.52	97	48	0	16	112	14	110	3e-30	119
rs:WP_029071998	phosphoribosyl-ATP pyrophosphatase [Laceyella sacchari].	53.00	100	47	0	13	112	1	100	3e-30	118
rs:WP_040420364	phosphoribosyl-AMP cyclohydrolase, partial [Actinopolymorpha alba].	55.79	95	42	0	18	112	16	110	3e-30	116
rs:WP_044438365	phosphoribosyl-AMP cyclohydrolase [Agreia bicolorata].	57.45	94	40	0	19	112	16	109	3e-30	116
rs:WP_015251143	phosphoribosyl-AMP cyclohydrolase [Bacillus subtilis].	55.79	95	42	0	18	112	7	101	3e-30	119
rs:WP_025681428	phosphoribosyl-ATP pyrophosphatase [Paenibacillus massiliensis].	53.12	96	45	0	17	112	18	113	3e-30	119
rs:WP_021252845	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Paenibacillus].	50.52	97	48	0	16	112	14	110	3e-30	119
rs:WP_018792371	phosphoribosyl-AMP cyclohydrolase [Salinispora arenicola].	53.61	97	45	0	18	114	35	131	3e-30	117
rs:WP_046286267	phosphoribosyl-AMP cyclohydrolase [Mycobacterium sp. UM_NZ2].	58.95	95	39	0	18	112	13	107	3e-30	116
rs:WP_004916811	phosphoribosyl-AMP cyclohydrolase [Acinetobacter junii].	53.61	97	44	1	18	113	8	104	3e-30	119
rs:WP_005458385	phosphoribosyl-AMP cyclohydrolase [Saccharomonospora cyanea].	52.78	108	46	1	18	125	15	117	3e-30	116
tr:X1C1Q1_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_L05151 {ECO:0000313|EMBL:GAG78306.1}; Flags: Fragment;	51.52	99	48	0	25	123	1	99	3e-30	116
rs:WP_006371434	phosphoribosyl-AMP cyclohydrolase [Gordonia polyisoprenivorans].	55.56	99	44	0	16	114	9	107	3e-30	116
rs:WP_021029301	phosphoribosyl-AMP cyclohydrolase [Halorhabdus tiamatea].	50.00	108	54	0	10	117	6	113	3e-30	116
sp:HIS3_DESPS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	51.43	105	48	2	18	119	4	108	3e-30	116
rs:WP_008361094	phosphoribosyl-ATP pyrophosphatase [Bacillus xiamenensis].	55.79	95	42	0	18	112	7	101	3e-30	119
rs:WP_021744935	phosphoribosyl-ATP diphosphatase [Leptotrichia sp. oral taxon 879].	50.52	97	48	0	18	114	6	102	3e-30	119
rs:WP_028592887	phosphoribosyl-ATP pyrophosphatase [Paenibacillus panacisoli].	53.12	96	45	0	17	112	18	113	3e-30	119
rs:WP_045017324	phosphoribosyl-AMP cyclohydrolase [Agrobacterium sp. KFB 330].	51.28	117	51	2	19	129	24	140	3e-30	117
rs:WP_030471215	phosphoribosyl-AMP cyclohydrolase [Lechevalieria aerocolonigenes].	56.12	98	43	0	15	112	10	107	3e-30	116
rs:WP_046740789	phosphoribosyl-AMP cyclohydrolase [Lampropedia sp. CT6].	46.09	115	58	1	20	130	12	126	3e-30	116
rs:WP_026002673	phosphoribosyl-AMP cyclohydrolase [Sphingobium xenophagum].	52.94	102	48	0	15	116	10	111	3e-30	116
tr:K1ZTE1_9BACT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	51.52	99	47	1	23	120	46	144	3e-30	117
rs:WP_012186449	phosphoribosyl-AMP cyclohydrolase [Caldivirga maquilingensis].	52.29	109	52	0	4	112	10	118	3e-30	116
rs:WP_022608515	phosphoribosyl-ATP pyrophosphohydrolase [Rubidibacter lacunae].	54.55	99	44	1	18	115	17	115	3e-30	119
rs:WP_038652821	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium huakuii].	50.43	117	46	2	19	123	25	141	3e-30	117
rs:WP_035643098	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium sp. ORS 375].	49.09	110	53	1	19	125	17	126	3e-30	117
rs:WP_004694201	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Veillonella].	54.26	94	43	0	24	117	10	103	3e-30	115
rs:WP_040598211	phosphoribosyl-ATP diphosphatase [Patulibacter medicamentivorans].	53.06	98	46	0	15	112	2	99	3e-30	119
rs:WP_002444736	phosphoribosyl-AMP cyclohydrolase [Staphylococcus caprae].	52.69	93	44	0	24	116	10	102	3e-30	118
sp:HIS2_BACSU	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	55.79	95	42	0	18	112	7	101	3e-30	118
sp:HIS3_GEOSM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.51	99	48	1	23	120	10	108	3e-30	116
rs:WP_004957511	phosphoribosyl-AMP cyclohydrolase [Acinetobacter junii].	53.61	97	44	1	18	113	8	104	4e-30	119
rs:WP_007106064	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Alteromonadales].	50.96	104	51	0	10	113	18	121	4e-30	116
rs:WP_004958631	phosphoribosyl-AMP cyclohydrolase [Acinetobacter junii].	53.61	97	44	1	18	113	8	104	4e-30	119
rs:WP_041126474	phosphoribosyl-ATP diphosphatase [Sulfurovum sp. FS06-10].	50.51	99	49	0	18	116	3	101	4e-30	119
tr:X0RQ49_9GAMM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	54.55	99	44	1	16	113	8	106	4e-30	120
rs:WP_029318340	phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis].	55.79	95	42	0	18	112	7	101	4e-30	118
rs:WP_035057991	phosphoribosyl-AMP cyclohydrolase [Andreprevotia chitinilytica].	49.11	112	56	1	20	130	12	123	4e-30	116
tr:H0SQ44_9BRAD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	49.09	110	53	1	19	125	6	115	4e-30	116
rs:WP_024004912	phosphoribosyl-AMP cyclohydrolase [Advenella kashmirensis].	52.63	95	44	1	20	113	9	103	4e-30	116
rs:WP_010630439	phosphoribosyl-ATP pyrophosphatase [Sporolactobacillus vineae].	46.36	110	59	0	14	123	2	111	4e-30	119
rs:WP_041338851	phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis].	54.64	97	44	0	16	112	5	101	4e-30	118
rs:WP_039714960	imidazole glycerol phosphate synthase [Scytonema millei].	52.43	103	46	2	18	119	19	119	4e-30	119
rs:WP_029326533	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. m3-13].	51.52	99	48	0	18	116	6	104	4e-30	119
rs:WP_027422000	imidazole glycerol phosphate synthase [Lachnobacterium bovis].	53.33	90	42	0	25	114	1	90	4e-30	118
rs:WP_016654848	phosphoribosyl-AMP cyclohydrolase [Acinetobacter rudis].	55.67	97	42	1	18	113	10	106	4e-30	120
tr:X0QEN7_9GAMM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	54.55	99	44	1	16	113	8	106	4e-30	120
rs:WP_035076218	phosphoribosyl-AMP cyclohydrolase [Caulobacter henricii].	53.27	107	48	1	14	118	19	125	4e-30	116
rs:WP_037322837	phosphoribosyl-AMP cyclohydrolase [Ruminococcus sp. NK3A76].	53.68	95	44	0	20	114	15	109	4e-30	115
rs:WP_044917038	phosphoribosyl-AMP cyclohydrolase [Oribacterium sp. FC2011].	50.50	101	50	0	12	112	5	105	4e-30	116
sp:HIS3_AGRT5	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	51.28	117	51	2	19	129	24	140	4e-30	117
rs:WP_036899006	phosphoribosyl-AMP cyclohydrolase, partial [Propionibacterium sp. oral taxon 192].	52.34	107	48	1	11	114	4	110	4e-30	115
rs:WP_042975259	phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis].	55.79	95	42	0	18	112	7	101	4e-30	118
rs:WP_018427738	phosphoribosyl-AMP cyclohydrolase [Hoeflea sp. 108].	50.00	114	53	2	17	126	23	136	4e-30	117
rs:WP_021953027	phosphoribosyl-ATP diphosphatase [Eubacterium sp. CAG:161].	51.96	102	49	0	12	113	206	307	4e-30	122
rs:WP_013418715	phosphoribosyl-AMP cyclohydrolase [Rhodomicrobium vannielii].	52.85	123	51	3	7	128	21	137	4e-30	116
rs:WP_043759872	phosphoribosyl-AMP cyclohydrolase [Methylobacterium oryzae].	51.79	112	47	2	7	116	19	125	4e-30	116
rs:WP_039393598	phosphoribosyl-AMP cyclohydrolase [Pandoraea sputorum].	50.00	104	51	1	18	120	9	112	4e-30	116
rs:WP_005588366	phosphoribosyl-AMP cyclohydrolase [Clostridium ultunense].	51.49	101	49	0	13	113	2	102	4e-30	118
tr:G0LZD3_LACPE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	53.19	94	44	0	24	117	10	103	4e-30	115
rs:WP_015933477	phosphoribosyl-AMP cyclohydrolase [Methylobacterium nodulans].	55.88	102	43	1	17	116	21	122	4e-30	116
rs:WP_023960969	phosphoribosyl-AMP cyclohydrolase [Williamsia sp. D3].	57.89	95	40	0	18	112	11	105	4e-30	115
rs:WP_015769453	phosphoribosyl-ATP pyrophosphatase [Leptotrichia buccalis].	50.52	97	48	0	18	114	6	102	4e-30	119
rs:WP_014360302	phosphoribosyl-AMP cyclohydrolase [Gordonia polyisoprenivorans].	55.56	99	44	0	16	114	9	107	4e-30	116
rs:WP_041399929	imidazole glycerol phosphate synthase [Sphaerobacter thermophilus].	50.48	105	49	1	11	112	1	105	4e-30	119
rs:WP_003886203	phosphoribosyl-AMP cyclohydrolase [Mycobacterium phlei].	52.38	105	49	1	9	112	2	106	4e-30	116
rs:WP_030271963	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Micromonospora].	52.53	99	47	0	16	114	28	126	4e-30	116
rs:WP_025040766	phosphoribosyl-AMP cyclohydrolase [Nitrosospira briensis].	44.07	118	65	1	12	128	3	120	4e-30	116
rs:WP_029721367	phosphoribosyl-AMP cyclohydrolase [Saccharopolyspora rectivirgula].	56.19	105	45	1	18	121	12	116	4e-30	116
rs:WP_027888749	MULTISPECIES: imidazole glycerol phosphate synthase [Meiothermus].	49.50	101	51	0	13	113	1	101	4e-30	118
tr:B3T631_9ARCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	44.04	109	60	1	11	118	1	109	4e-30	115
rs:WP_018984757	phosphoribosyl-AMP cyclohydrolase [Salinimonas chungwhensis].	57.14	91	39	0	24	114	18	108	4e-30	118
rs:WP_009440154	phosphoribosyl-ATP diphosphatase [Selenomonas sp. oral taxon 138].	50.00	102	50	1	11	112	1	101	4e-30	119
rs:WP_031545388	hypothetical protein [Lachnospiraceae bacterium AC2014].	52.34	107	51	0	10	116	215	321	4e-30	122
rs:WP_018899914	phosphoribosyl-AMP cyclohydrolase [Rhizobium sp. 2MFCol3.1].	50.42	119	53	3	17	131	23	139	4e-30	117
rs:WP_014092004	phosphoribosyl-AMP cyclohydrolase [Listeria ivanovii].	50.00	102	50	1	17	118	3	103	4e-30	115
rs:WP_007957654	phosphoribosyl-ATP pyrophosphatase [Pelosinus fermentans].	55.79	95	42	0	18	112	7	101	4e-30	119
rs:WP_043858756	phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis].	55.79	95	42	0	18	112	7	101	4e-30	118
rs:WP_030500287	phosphoribosyl-AMP cyclohydrolase [Micromonospora purpureochromogenes].	53.61	97	45	0	18	114	30	126	4e-30	116
tr:F5JEI5_9RHIZ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	51.28	117	51	2	19	129	40	156	4e-30	117
rs:WP_007545276	phosphoribosyl-AMP cyclohydrolase [Listeria fleischmannii].	54.17	96	43	1	17	112	2	96	4e-30	115
rs:WP_032722598	phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis].	55.79	95	42	0	18	112	7	101	4e-30	118
rs:WP_014424721	phosphoribosyl-ATP pyrophosphatase [Selenomonas ruminantium].	50.50	101	49	1	12	112	3	102	4e-30	119
rs:WP_043350207	phosphoribosyl-AMP cyclohydrolase [Cupriavidus basilensis].	48.60	107	54	1	16	121	7	113	4e-30	116
rs:WP_002277850	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	51.58	95	46	0	22	116	11	105	4e-30	115
rs:WP_026826109	phosphoribosyl-AMP cyclohydrolase [Exiguobacterium marinum].	50.51	99	49	0	18	116	10	108	4e-30	115
rs:WP_029508157	phosphoribosyl-AMP cyclohydrolase [Lactobacillus versmoldensis].	52.04	98	47	0	24	121	8	105	4e-30	115
rs:WP_041799308	phosphoribosyl-AMP cyclohydrolase [Micromonospora aurantiaca].	52.53	99	47	0	16	114	28	126	4e-30	116
rs:WP_015767450	phosphoribosyl-AMP cyclohydrolase [Candidatus Accumulibacter phosphatis].	52.53	99	46	1	23	120	10	108	4e-30	116
sp:HIS3_NITOC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	51.49	101	48	1	20	119	11	111	4e-30	116
rs:WP_041962674	phosphoribosyl-ATP diphosphatase [Sulfurospirillum cavolei].	53.92	102	47	0	16	117	7	108	4e-30	119
rs:WP_020453064	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacillus subtilis group].	54.74	95	43	0	18	112	7	101	4e-30	118
rs:WP_037061664	phosphoribosyl-AMP cyclohydrolase [Rhizobium leguminosarum].	50.42	119	53	3	17	131	22	138	4e-30	117
rs:WP_034777391	phosphoribosyl-AMP cyclohydrolase [Exiguobacterium mexicanum].	50.00	100	50	0	18	117	10	109	4e-30	115
rs:WP_019320895	phosphoribosyl-AMP cyclohydrolase, partial [Streptococcus mutans].	52.13	94	45	0	21	114	10	103	4e-30	115
rs:WP_003639300	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Lactobacillus].	53.19	94	44	0	24	117	10	103	4e-30	115
rs:WP_034475029	hypothetical protein [Butyrivibrio proteoclasticus].	52.48	101	48	0	13	113	219	319	4e-30	122
tr:F7PK53_9EURY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	50.00	108	54	0	10	117	15	122	4e-30	116
rs:WP_020215709	phosphoribosyl-AMP cyclohydrolase [Salinispora arenicola].	53.61	97	45	0	18	114	35	131	4e-30	116
tr:A0A066TUZ4_9NEIS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	50.45	111	54	1	11	120	1	111	4e-30	116
rs:WP_026267834	phosphoribosyl-AMP cyclohydrolase [Micromonospora sp. CNB394].	48.62	109	56	0	16	124	28	136	4e-30	116
rs:WP_024897165	phosphoribosyl-AMP cyclohydrolase [Ochrobactrum rhizosphaerae].	51.79	112	50	2	19	126	23	134	4e-30	116
rs:WP_018726718	phosphoribosyl-AMP cyclohydrolase [Salinispora pacifica].	54.64	97	44	0	18	114	35	131	4e-30	116
rs:WP_006635030	phosphoribosyl-ATP pyrophosphatase [Microcoleus vaginatus].	54.55	99	44	1	18	115	18	116	5e-30	118
rs:WP_006419730	phosphoribosyl-AMP cyclohydrolase [delta proteobacterium NaphS2].	49.22	128	59	4	5	130	3	126	5e-30	116
rs:WP_007473567	phosphoribosyl-AMP cyclohydrolase [Listeria fleischmannii].	56.18	89	39	0	24	112	8	96	5e-30	115
rs:WP_037997438	phosphoribosyl-ATP pyrophosphatase [Thermoactinomyces sp. Gus2-1].	50.00	108	54	0	18	125	7	114	5e-30	118
rs:WP_040656802	phosphoribosyl-AMP cyclohydrolase [Olsenella sp. oral taxon 809].	49.04	104	53	0	13	116	1	104	5e-30	116
rs:WP_014481010	phosphoribosyl-AMP cyclohydrolase [Bacillus subtilis].	55.79	95	42	0	18	112	7	101	5e-30	118
rs:WP_013280838	imidazole glycerol phosphate synthase [Butyrivibrio proteoclasticus].	52.48	101	48	0	13	113	230	330	5e-30	122
rs:WP_010240636	phosphoribosyl-AMP cyclohydrolase [Clostridium arbusti].	52.13	94	45	0	24	117	15	108	5e-30	115
rs:WP_045473454	phosphoribosyl-AMP cyclohydrolase [Thioploca ingrica].	47.06	102	53	1	18	118	9	110	5e-30	116
rs:WP_038286157	phosphoribosyl-AMP cyclohydrolase [actinobacterium acAcidi].	56.57	99	42	1	16	113	9	107	5e-30	115
rs:WP_034131191	phosphoribosyl-ATP pyrophosphatase [Peptococcaceae bacterium BICA1-8].	50.00	100	50	0	13	112	4	103	5e-30	118
rs:WP_014236515	phosphoribosyl-AMP cyclohydrolase [Azospira oryzae].	51.85	108	46	2	12	113	4	111	5e-30	116
rs:WP_045022638	phosphoribosyl-AMP cyclohydrolase [Rhizobium nepotum].	51.28	117	51	2	19	129	24	140	5e-30	116
rs:WP_037405302	phosphoribosyl-AMP cyclohydrolase, partial [Snodgrassella alvi].	51.89	106	50	1	16	120	7	112	5e-30	116
rs:WP_025646054	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Psychrobacter].	53.54	99	45	1	16	113	8	106	5e-30	120
rs:WP_024061549	phosphoribosyl-AMP cyclohydrolase [Veillonella dispar].	54.26	94	43	0	24	117	10	103	5e-30	115
rs:WP_036221127	phosphoribosyl-ATP pyrophosphatase [Lysinibacillus sphaericus].	48.08	104	54	0	18	121	5	108	5e-30	118
rs:WP_004077675	phosphoribosyl-AMP cyclohydrolase [Methanoplanus limicola].	50.00	100	50	0	18	117	3	102	5e-30	115
rs:WP_007208991	phosphoribosyl-AMP cyclohydrolase [Enterococcus italicus].	53.40	103	47	1	15	116	3	105	5e-30	115
rs:WP_044998701	phosphoribosyl-ATP diphosphatase [Roseburia intestinalis].	49.57	117	57	1	16	130	207	323	5e-30	121
tr:C7G7S0_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	49.57	117	57	1	16	130	227	343	5e-30	122
rs:WP_006441445	imidazole glycerol phosphate synthase [[Clostridium] hylemonae].	54.29	105	46	1	9	113	222	324	5e-30	122
rs:WP_002298584	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	51.58	95	46	0	22	116	11	105	5e-30	115
rs:WP_015483748	phosphoribosyl-AMP cyclohydrolase [Bacillus subtilis].	54.74	95	43	0	18	112	7	101	5e-30	118
rs:WP_019318600	phosphoribosyl-AMP cyclohydrolase, partial [Streptococcus mutans].	52.13	94	45	0	21	114	10	103	5e-30	115
rs:WP_021748143	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Oscillibacter].	53.54	99	46	0	18	116	3	101	5e-30	118
rs:WP_045073689	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. IHBB 11108].	53.68	95	44	0	18	112	20	114	5e-30	116
rs:WP_039598757	phosphoribosyl-AMP cyclohydrolase [Ralstonia sp. A12].	45.79	107	57	1	16	121	7	113	5e-30	116
rs:WP_027052092	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium loti].	49.57	117	47	2	19	123	25	141	5e-30	116
rs:WP_010740006	phosphoribosyl-ATP diphosphatase [Enterococcus malodoratus].	45.22	115	63	0	16	130	2	116	5e-30	118
rs:WP_015230215	phosphoribosyl-AMP cyclohydrolase [Dactylococcopsis salina].	54.37	103	45	1	19	119	23	125	5e-30	117
rs:WP_022859473	phosphoribosyl-AMP cyclohydrolase [Bifidobacterium magnum].	54.64	97	44	0	16	112	18	114	5e-30	115
rs:WP_037383125	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Sinorhizobium].	51.33	113	51	2	17	125	22	134	5e-30	116
rs:WP_022092561	phosphoribosyl-AMP cyclohydrolase [Firmicutes bacterium CAG:536].	52.13	94	45	0	24	117	11	104	5e-30	115
rs:WP_002276906	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	51.58	95	46	0	22	116	11	105	5e-30	115
sp:HIS3_SACEN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	55.79	95	42	0	18	112	13	107	5e-30	115
rs:WP_021147594	phosphoribosyl-AMP cyclohydrolase [Veillonella parvula].	53.19	94	44	0	24	117	10	103	5e-30	115
rs:WP_028505605	phosphoribosyl-AMP cyclohydrolase [Ruminococcus sp. FC2018].	54.74	95	43	0	20	114	15	109	5e-30	115
rs:WP_018407866	phosphoribosyl-AMP cyclohydrolase [Methylocystis rosea].	52.25	111	50	2	19	126	17	127	5e-30	115
rs:WP_025779830	phosphoribosyl-AMP cyclohydrolase [Dehalococcoidia bacterium DscP2].	52.53	99	47	0	15	113	2	100	5e-30	115
rs:WP_020202040	phosphoribosyl-AMP cyclohydrolase [Cupriavidus sp. WS].	48.60	107	54	1	16	121	7	113	5e-30	116
sp:HIS3_RALSO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	46.73	107	56	1	16	121	7	113	5e-30	116
rs:WP_007357184	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Kamptonema].	50.43	115	49	2	9	115	2	116	5e-30	118
rs:WP_014478094	phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis].	54.74	95	43	0	18	112	7	101	5e-30	118
rs:WP_041518070	phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis].	54.74	95	43	0	18	112	7	101	5e-30	118
rs:WP_021154624	phosphoribosyl-AMP cyclohydrolase [Ralstonia solanacearum].	46.73	107	56	1	16	121	7	113	5e-30	116
rs:WP_018759076	hypothetical protein [Paenibacillus terrigena].	49.02	102	52	0	15	116	18	119	5e-30	119
rs:WP_015560559	phosphoribosyl-ATP pyrophosphohydrolase [Roseburia intestinalis CAG:13].	49.57	117	57	1	16	130	227	343	5e-30	121
rs:WP_017756382	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. ZYK].	49.06	106	54	0	13	118	1	106	5e-30	118
tr:A0A094QBH8_9ZZZZ	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGA20762.1};	53.33	90	42	0	24	113	18	107	6e-30	115
rs:WP_007875047	phosphoribosyl-AMP cyclohydrolase [Ochrobactrum sp. CDB2].	51.79	112	50	2	19	126	23	134	6e-30	116
rs:WP_010842331	phosphoribosyl-AMP cyclohydrolase [Gordonia terrae].	53.77	106	48	1	10	114	2	107	6e-30	116
rs:WP_031470697	phosphoribosyl-AMP cyclohydrolase [Sciscionella sp. SE31].	56.57	99	43	0	18	116	7	105	6e-30	115
rs:WP_014890348	phosphoribosyl-AMP cyclohydrolase [Methylocystis sp. SC2].	54.29	105	45	2	19	120	17	121	6e-30	115
tr:A0A094Q279_9ZZZZ	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGA16169.1};	51.61	93	45	0	21	113	6	98	6e-30	115
rs:WP_036577088	phosphoribosyl-ATP pyrophosphatase [Oceanobacillus picturae].	45.05	111	61	0	11	121	1	111	6e-30	118
rs:WP_036182820	phosphoribosyl-ATP pyrophosphatase [Lysinibacillus manganicus].	51.04	96	47	0	17	112	6	101	6e-30	118
rs:WP_009289799	imidazole glycerol phosphate synthase [Anaerostipes sp. CAG:276].	53.77	106	47	1	9	114	206	309	6e-30	121
rs:WP_014463793	phosphoribosyl-ATP diphosphatase [Alicyclobacillus acidocaldarius].	50.00	110	53	2	12	119	7	116	6e-30	119
rs:WP_014848255	phosphoribosyl-AMP cyclohydrolase [Zymomonas mobilis].	53.00	100	47	0	20	119	15	114	6e-30	115
sp:HIS3_ZYMMO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.00	100	47	0	20	119	15	114	6e-30	115
rs:WP_021288693	hypothetical protein [Virgibacillus sp. CM-4].	48.11	106	55	0	11	116	1	106	6e-30	118
rs:WP_010059919	phosphoribosyl-AMP cyclohydrolase [Rhizobium etli].	50.43	117	56	1	17	131	23	139	6e-30	116
rs:WP_019770322	phosphoribosyl-AMP cyclohydrolase [Streptococcus sobrinus].	51.43	105	45	1	10	114	5	103	6e-30	115
rs:WP_036651351	phosphoribosyl-ATP pyrophosphatase [Paenibacillus wynnii].	53.12	96	45	0	18	113	19	114	6e-30	119
rs:WP_014516055	phosphoribosyl-ATP pyrophosphatase [Thermus sp. CCB_US3_UF1].	46.02	113	61	0	13	125	1	113	6e-30	118
rs:WP_003718681	phosphoribosyl-AMP cyclohydrolase [Listeria ivanovii].	51.58	95	46	0	24	118	9	103	6e-30	115
rs:WP_003923880	phosphoribosyl-AMP cyclohydrolase [Mycobacterium thermoresistibile].	54.74	95	43	0	18	112	11	105	6e-30	115
rs:WP_042204655	phosphoribosyl-ATP pyrophosphatase [Paenibacillus durus].	48.25	114	59	0	18	131	19	132	6e-30	119
rs:WP_038245782	phosphoribosyl-ATP pyrophosphatase [Virgibacillus sp. Vm-5].	48.11	106	55	0	11	116	1	106	6e-30	118
rs:WP_039248994	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	54.64	97	43	1	18	113	8	104	6e-30	119
rs:WP_020747342	phosphoribosyl-AMP cyclohydrolase [Ralstonia solanacearum].	46.73	107	56	1	16	121	7	113	6e-30	116
rs:WP_018586720	phosphoribosyl-AMP cyclohydrolase [Salinispora arenicola].	53.61	97	45	0	18	114	35	131	6e-30	116
tr:A0A075H8T6_9ARCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	41.82	110	63	1	11	119	1	110	6e-30	115
rs:WP_034292826	phosphoribosyl-AMP cyclohydrolase [Alysiella crassa].	47.54	122	63	1	11	131	1	122	6e-30	115
rs:WP_009661708	phosphoribosyl-AMP cyclohydrolase [Veillonella sp. ACP1].	54.55	99	44	1	20	117	5	103	6e-30	115
sp:HIS3_RHIE6	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.00	124	57	2	10	131	19	139	6e-30	116
sp:HIS3_CHESB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.68	112	49	2	17	124	25	136	6e-30	116
rs:WP_019805425	phosphoribosyl-AMP cyclohydrolase, partial [Streptococcus mutans].	52.13	94	45	0	21	114	10	103	6e-30	115
rs:WP_007740079	phosphoribosyl-AMP cyclohydrolase [Halococcus thailandensis].	53.12	96	45	0	18	113	10	105	6e-30	115
rs:WP_041139567	imidazole glycerol phosphate synthase [Clostridiaceae bacterium GM1].	48.57	105	53	1	20	124	5	108	6e-30	118
rs:WP_013441101	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Methylovorus].	50.00	102	50	1	18	118	9	110	6e-30	115
tr:A0A097AT49_THEKI	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	50.00	100	50	0	14	113	3	102	6e-30	118
rs:WP_024709252	phosphoribosyl-AMP cyclohydrolase [Martelella sp. AD-3].	53.70	108	46	2	17	120	21	128	6e-30	116
rs:WP_038537311	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. X1(2014)].	53.12	96	45	0	17	112	5	100	6e-30	118
gp:AF088896_7	phosphoribosyl c-AMP cyclohydrolase [Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821]	53.00	100	47	0	20	119	15	114	6e-30	115
rs:WP_034795960	phosphoribosyl-AMP cyclohydrolase [Ensifer adhaerens].	51.26	119	52	3	17	129	22	140	6e-30	116
rs:WP_019259567	phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis].	54.74	95	43	0	18	112	7	101	7e-30	117
rs:WP_023073439	phosphoribosyl-amp cyclohydrolase [Leptolyngbya sp. Heron Island J].	55.05	109	46	2	19	124	23	131	7e-30	116
rs:WP_004794990	phosphoribosyl-ATP diphosphatase [Acinetobacter sp. NIPH 817].	53.61	97	44	1	18	113	8	104	7e-30	119
rs:WP_026597023	phosphoribosyl-AMP cyclohydrolase [Methylobacterium sp. 77].	55.88	102	43	1	17	116	21	122	7e-30	115
rs:WP_005387495	phosphoribosyl-AMP cyclohydrolase [Veillonella dispar].	54.26	94	43	0	24	117	10	103	7e-30	115
rs:WP_014615972	phosphoribosyl-AMP cyclohydrolase [Ralstonia solanacearum].	46.73	107	56	1	16	121	7	113	7e-30	116
rs:WP_018684491	phosphoribosyl-AMP cyclohydrolase [Actinokineospora enzanensis].	55.79	95	42	0	18	112	11	105	7e-30	115
rs:WP_006239765	phosphoribosyl-AMP cyclohydrolase [Saccharomonospora xinjiangensis].	51.85	108	47	1	18	125	12	114	7e-30	115
tr:B0MDQ3_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	53.77	106	47	1	9	114	206	309	7e-30	121
tr:D4XM07_ACIHA	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	50.46	109	48	2	11	113	1	109	7e-30	119
rs:WP_024877218	phosphoribosyl-AMP cyclohydrolase [Saccharomonospora sp. CNQ490].	50.85	118	52	2	9	125	2	114	7e-30	115
rs:WP_044024911	hypothetical protein [Roseburia hominis].	45.93	135	66	3	3	130	199	333	7e-30	121
rs:WP_004777837	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. CIP 102082].	53.61	97	44	1	18	113	8	104	7e-30	119
rs:WP_021042413	phosphoribosyl-AMP cyclohydrolase [halophilic archaeon J07HX64].	54.37	103	46	1	11	113	10	111	7e-30	115
rs:WP_041397052	phosphoribosyl-AMP cyclohydrolase [Polynucleobacter necessarius].	47.79	113	54	2	2	113	1	109	7e-30	115
rs:WP_016251893	phosphoribosyl-ATP diphosphatase [Enterococcus cecorum].	47.41	116	59	1	13	126	2	117	7e-30	118
rs:WP_019715834	phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis].	54.74	95	43	0	18	112	7	101	7e-30	117
rs:WP_033925949	phosphoribosyl-AMP cyclohydrolase [Sphingomonas sp. 35-24ZXX].	55.14	107	46	2	19	123	14	120	7e-30	115
rs:WP_025617932	phosphoribosyl-AMP cyclohydrolase [Salinispora pacifica].	53.61	97	45	0	18	114	35	131	7e-30	116
rs:WP_014063337	phosphoribosyl-ATP pyrophosphatase [Thermoanaerobacter wiegelii].	49.00	100	51	0	14	113	3	102	7e-30	118
rs:WP_008942288	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Acinetobacter].	53.61	97	44	1	18	113	8	104	7e-30	119
rs:WP_005162890	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. NIPH 284].	53.61	97	44	1	18	113	8	104	7e-30	119
rs:WP_042210014	phosphoribosyl-ATP pyrophosphatase [Paenibacillus borealis].	53.06	98	46	0	16	113	17	114	7e-30	118
rs:WP_004674427	phosphoribosyl-AMP cyclohydrolase [Acinetobacter parvus].	53.61	97	44	1	18	113	8	104	7e-30	119
rs:WP_044454614	phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis].	54.74	95	43	0	18	112	7	101	7e-30	117
rs:WP_039741818	phosphoribosyl-AMP cyclohydrolase [Geobacter pickeringii].	53.06	98	45	1	23	119	10	107	7e-30	115
rs:WP_043067715	phosphoribosyl-ATP pyrophosphatase [Aneurinibacillus migulanus].	50.93	108	52	1	18	124	6	113	7e-30	118
rs:WP_022166123	phosphoribosyl-ATP diphosphatase [Eubacterium sp. CAG:192].	50.48	105	50	1	9	113	202	304	7e-30	121
rs:WP_004756279	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Acinetobacter].	53.61	97	44	1	18	113	8	104	7e-30	119
gpu:CP009515_2571	Phosphoribosyl-AMP cyclohydrolase [Methanosarcina lacustris Z-7289]	52.34	107	48	2	11	117	2	105	7e-30	115
rs:WP_046763249	phosphoribosyl-AMP cyclohydrolase [Sphingobium chungbukense].	53.54	99	46	0	15	113	10	108	7e-30	115
rs:WP_005838288	phosphoribosyl-ATP pyrophosphatase [Eubacterium saphenum].	45.69	116	61	1	18	131	4	119	7e-30	118
rs:WP_004762269	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. CIP 102129].	53.61	97	44	1	18	113	8	104	7e-30	119
rs:WP_046739331	phosphoribosyl-ATP diphosphatase [Acinetobacter sp. AG1].	53.61	97	44	1	18	113	8	104	7e-30	119
rs:WP_007132973	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillales].	50.98	102	50	0	18	119	18	119	7e-30	118
rs:WP_002598408	hypothetical protein [Clostridium colicanis].	49.47	95	48	0	24	118	13	107	7e-30	115
rs:WP_043801236	imidazole glycerol phosphate synthase [Deinococcus gobiensis].	53.40	103	48	0	11	113	1	103	7e-30	118
rs:WP_017394865	phosphoribosyl-ATP diphosphatase [Acinetobacter haemolyticus].	53.61	97	44	1	18	113	8	104	7e-30	119
rs:WP_004680688	phosphoribosyl-AMP cyclohydrolase [Acinetobacter parvus].	53.61	97	44	1	18	113	8	104	7e-30	119
rs:WP_038845590	phosphoribosyl-AMP cyclohydrolase [Salinispora pacifica].	52.00	100	48	0	18	117	35	134	7e-30	116
rs:WP_013150712	phosphoribosyl-ATP pyrophosphatase [Thermoanaerobacter mathranii].	50.00	100	50	0	14	113	3	102	8e-30	118
rs:WP_037128010	phosphoribosyl-AMP cyclohydrolase [Rhizobium sp. CF394].	49.57	117	57	1	17	131	23	139	8e-30	116
rs:WP_009395539	phosphoribosyl-AMP cyclohydrolase [Actinomyces sp. oral taxon 171].	51.89	106	51	0	15	120	8	113	8e-30	115
rs:WP_005255455	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. NIPH 2168].	53.61	97	44	1	18	113	8	104	8e-30	119
rs:WP_031580734	imidazole glycerol phosphate synthase [Lachnospiraceae bacterium AC2028].	53.54	99	46	0	16	114	12	110	8e-30	117
rs:WP_045553566	phosphoribosyl-AMP cyclohydrolase [Listeria innocua].	48.54	103	52	1	16	118	2	103	8e-30	114
rs:WP_026747375	phosphoribosyl-ATP pyrophosphatase [Leptotrichia trevisanii].	48.51	101	52	0	14	114	2	102	8e-30	118
rs:WP_043071510	phosphoribosyl-ATP pyrophosphatase [Aneurinibacillus migulanus].	50.93	108	52	1	18	124	6	113	8e-30	118
rs:WP_021037253	phosphoribosyl-AMP cyclohydrolase [Lactococcus lactis].	54.64	97	44	0	20	116	5	101	8e-30	117
rs:WP_003539878	phosphoribosyl-AMP cyclohydrolase [Rhizobium leguminosarum].	49.57	117	57	1	17	131	23	139	8e-30	116
rs:WP_005226467	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Acinetobacter].	53.61	97	44	1	18	113	8	104	8e-30	119
rs:WP_046160888	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. CMAA 1185].	54.74	95	43	0	18	112	7	101	8e-30	117
rs:WP_004680212	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Rhizobium].	50.00	124	57	2	10	131	19	139	8e-30	116
rs:WP_005088019	phosphoribosyl-AMP cyclohydrolase [Acinetobacter haemolyticus].	53.61	97	44	1	18	113	8	104	8e-30	119
rs:WP_020921346	phosphoribosyl-AMP cyclohydrolase [Rhizobium etli].	50.00	124	57	2	10	131	19	139	8e-30	116
rs:WP_004774116	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. NIPH 758].	53.61	97	44	1	18	113	8	104	8e-30	119
rs:WP_045385155	phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis].	54.74	95	43	0	18	112	7	101	8e-30	117
sp:HIS2_GLOVI	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	57.29	96	40	1	19	113	22	117	8e-30	118
tr:A0A094Q9E1_9ACTN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.89	95	39	1	20	113	3	97	8e-30	114
tr:T0SGE4_LACLC	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	53.61	97	45	0	20	116	5	101	8e-30	117
rs:WP_005083825	phosphoribosyl-AMP cyclohydrolase [Acinetobacter haemolyticus].	53.61	97	44	1	18	113	8	104	8e-30	119
rs:WP_021585131	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Ochrobactrum].	51.79	112	50	2	19	126	23	134	8e-30	115
rs:WP_044429481	phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis].	54.74	95	43	0	18	112	7	101	8e-30	117
rs:WP_009727600	phosphoribosyl-AMP cyclohydrolase, partial [Methylophaga lonarensis].	46.49	114	60	1	18	130	8	121	8e-30	115
rs:WP_006698834	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Rhizobium/Agrobacterium group].	52.99	117	49	3	19	129	24	140	8e-30	116
rs:WP_005240057	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Acinetobacter].	53.61	97	44	1	18	113	8	104	8e-30	119
rs:WP_005200473	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Acinetobacter].	53.61	97	44	1	18	113	8	104	8e-30	119
rs:WP_023053776	phosphoribosyl-ATP diphosphatase [Megasphaera sp. BV3C16-1].	49.48	97	49	0	17	113	8	104	8e-30	118
tr:A0A0B0KJT5_9GAMM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	53.61	97	44	1	18	113	8	104	8e-30	119
rs:WP_009514250	phosphoribosyl-ATP diphosphatase [Acinetobacter sp. WC-323].	53.61	97	44	1	18	113	8	104	8e-30	119
rs:WP_005314971	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. ANC 3880].	53.61	97	44	1	18	113	8	104	8e-30	119
rs:WP_005191993	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. ANC 4105].	53.61	97	44	1	18	113	8	104	8e-30	119
rs:WP_032870588	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	53.61	97	44	1	18	113	8	104	8e-30	119
rs:WP_036625902	phosphoribosyl-ATP pyrophosphatase [Paenibacillus barengoltzii].	52.58	97	46	0	17	113	13	109	8e-30	118
rs:WP_014115292	phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis].	54.74	95	43	0	18	112	7	101	8e-30	117
rs:WP_005061085	phosphoribosyl-AMP cyclohydrolase [Acinetobacter beijerinckii].	53.61	97	44	1	18	113	8	104	8e-30	119
rs:WP_041838438	phosphoribosyl-AMP cyclohydrolase [Actinosynnema mirum].	56.84	95	41	0	18	112	11	105	8e-30	115
rs:WP_021994490	histidine biosynthesis protein HisIE [Prevotella sp. CAG:487].	56.67	90	39	0	23	112	9	98	8e-30	117
rs:WP_008810512	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Parasutterella].	54.64	97	43	1	18	113	5	101	8e-30	115
rs:WP_005154918	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. ANC 3929].	53.61	97	44	1	18	113	8	104	8e-30	119
rs:WP_004876516	phosphoribosyl-AMP cyclohydrolase [Acinetobacter venetianus].	53.61	97	44	1	18	113	8	104	8e-30	119
rs:WP_044958773	hypothetical protein [Shuttleworthia sp. MSX8B].	50.00	114	54	2	16	126	24	137	8e-30	115
rs:WP_003219809	phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis].	54.74	95	43	0	18	112	7	101	8e-30	117
tr:G2SWS6_ROSHA	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	45.93	135	66	3	3	130	208	342	8e-30	121
rs:WP_027649182	phosphoribosyl-AMP cyclohydrolase [Salinispora pacifica].	53.61	97	45	0	18	114	35	131	8e-30	115
rs:WP_006039604	phosphoribosyl-ATP pyrophosphatase [Paenibacillus curdlanolyticus].	50.00	104	51	1	18	120	19	122	8e-30	118
tr:S0DFG8_9ZZZZ	SubName: Full=Putative histidine biosynthesis protein {ECO:0000313|EMBL:CCO20910.1};	50.50	101	50	0	13	113	2	102	8e-30	117
tr:T2JBA9_CROWT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	51.40	107	50	1	19	123	23	129	8e-30	116
rs:WP_006836857	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. SG-1].	51.58	95	46	0	18	112	8	102	8e-30	117
rs:WP_041227568	imidazole glycerol phosphate synthase [Deinococcus deserti].	51.43	105	51	0	14	118	3	107	8e-30	118
rs:WP_023013142	phosphoribosyl-ATP diphosphatase [Acinetobacter sp. COS3].	53.61	97	44	1	18	113	8	104	8e-30	119
rs:WP_042231571	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. FSL R5-0912].	53.06	98	46	0	16	113	17	114	8e-30	118
rs:WP_042132745	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. FSL P4-0081].	53.06	98	46	0	16	113	17	114	8e-30	118
rs:WP_044505430	imidazole glycerol phosphate synthase [Megasphaera sp. NP3].	50.00	96	48	0	18	113	9	104	8e-30	118
tr:C1CX55_DEIDV	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	51.43	105	51	0	14	118	5	109	8e-30	118
rs:WP_007480101	phosphoribosyl-ATP diphosphatase [Acinetobacter sp. NBRC 100985].	53.61	97	44	1	18	113	8	104	8e-30	119
rs:WP_019385808	phosphoribosyl-ATP diphosphatase [Acinetobacter venetianus].	53.61	97	44	1	18	113	8	104	8e-30	119
tr:C6WCD3_ACTMD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	56.84	95	41	0	18	112	10	104	8e-30	115
rs:WP_041906442	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. BSC154].	54.74	95	43	0	18	112	7	101	8e-30	117
rs:WP_025880686	phosphoribosyl-ATP pyrophosphatase [Prevotella baroniae].	54.64	97	43	1	17	112	2	98	8e-30	117
rs:WP_018736222	phosphoribosyl-AMP cyclohydrolase [Salinispora pacifica].	53.61	97	45	0	18	114	35	131	8e-30	115
rs:WP_012971967	phosphoribosyl-AMP cyclohydrolase [Allochromatium vinosum].	51.89	106	50	1	9	113	2	107	8e-30	115
rs:WP_016165072	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. CIP 110321].	53.61	97	44	1	18	113	8	104	8e-30	119
rs:WP_018242117	phosphoribosyl-AMP cyclohydrolase [Rhizobium leguminosarum].	49.57	117	57	1	17	131	23	139	8e-30	116
rs:WP_018821154	phosphoribosyl-AMP cyclohydrolase [Salinispora pacifica].	53.61	97	45	0	18	114	35	131	9e-30	115
rs:WP_007305159	phosphoribosyl-AMP cyclohydrolase [Crocosphaera watsonii].	51.40	107	50	1	19	123	23	129	9e-30	116
rs:WP_019203055	phosphoribosyl-AMP cyclohydrolase [Tsukamurella sp. 1534].	55.79	95	42	0	18	112	14	108	9e-30	115
rs:WP_005210179	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. NIPH 1867].	53.61	97	44	1	18	113	8	104	9e-30	119
rs:WP_018223304	phosphoribosyl-AMP cyclohydrolase [Salinispora pacifica].	53.61	97	45	0	18	114	35	131	9e-30	115
rs:WP_027655450	phosphoribosyl-AMP cyclohydrolase [Salinispora pacifica].	53.61	97	45	0	18	114	35	131	9e-30	115
rs:WP_044012182	phosphoribosyl-ATP pyrophosphatase [Legionella massiliensis].	51.40	107	51	1	12	117	3	109	9e-30	117
rs:WP_006575776	phosphoribosyl-AMP cyclohydrolase [Cupriavidus sp. HPC(L)].	45.83	120	60	2	16	130	7	126	9e-30	115
rs:WP_019868858	phosphoribosyl-AMP cyclohydrolase [Salinispora pacifica].	53.61	97	45	0	18	114	35	131	9e-30	115
rs:WP_009155427	phosphoribosyl-AMP cyclohydrolase [Saccharomonospora marina].	52.78	108	46	1	18	125	13	115	9e-30	115
rs:WP_038829462	phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis].	54.74	95	43	0	18	112	7	101	9e-30	117
tr:E8KUM4_STRVE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	48.15	108	50	1	11	118	7	108	9e-30	115
rs:WP_034574221	hypothetical protein, partial [Helicobacter sanguini].	48.65	111	55	1	18	126	8	118	9e-30	119
rs:WP_013008430	phosphoribosyl-AMP cyclohydrolase [Deferribacter desulfuricans].	52.22	90	43	0	24	113	15	104	9e-30	114
rs:WP_037621427	phosphoribosyl-AMP cyclohydrolase [Streptococcus vestibularis].	48.15	108	50	1	11	118	6	107	9e-30	115
rs:WP_010764074	phosphoribosyl-AMP cyclohydrolase [Enterococcus moraviensis].	51.61	93	45	0	24	116	8	100	9e-30	114
rs:WP_003745768	phosphoribosyl-AMP cyclohydrolase [Listeria seeligeri].	52.63	95	45	0	24	118	9	103	9e-30	114
rs:WP_003228125	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillus].	54.74	95	43	0	18	112	7	101	9e-30	117
rs:WP_021922769	hypothetical protein [Roseburia inulinivorans CAG:15].	43.88	139	65	2	2	127	209	347	9e-30	121
rs:WP_021144328	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptococcus].	52.04	98	47	0	21	118	10	107	9e-30	115
rs:WP_045533743	phosphoribosyl-AMP cyclohydrolase [Rhizobium sp. LMB-1].	52.99	117	49	3	19	129	24	140	9e-30	115
rs:WP_021590596	phosphoribosyl-ATP diphosphatase [Prevotella baroniae].	54.64	97	43	1	17	112	2	98	9e-30	117
rs:WP_018251639	phosphoribosyl-AMP cyclohydrolase [Salinispora pacifica].	53.61	97	45	0	18	114	35	131	9e-30	115
rs:WP_016139427	phosphoribosyl-ATP diphosphatase [Acinetobacter calcoaceticus].	53.61	97	44	1	18	113	8	104	9e-30	119
rs:WP_002998366	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptococcus].	54.55	99	44	1	17	114	5	103	9e-30	114
rs:WP_003235384	histidine biosynthesis bifunctional protein hisIE [Bacillus subtilis].	54.74	95	43	0	18	112	7	101	9e-30	117
rs:WP_024901931	phosphoribosyl-AMP cyclohydrolase [Burkholderia andropogonis].	51.55	97	46	1	18	113	23	119	9e-30	115
rs:WP_034804863	phosphoribosyl-AMP cyclohydrolase [Exiguobacterium sp. AB2].	49.00	100	51	0	18	117	10	109	9e-30	114
rs:WP_038324219	phosphoribosyl-AMP cyclohydrolase [bacterium MS4].	54.64	97	44	0	20	116	16	112	9e-30	115
rs:WP_018445264	phosphoribosyl-AMP cyclohydrolase [Rhizobium gallicum].	49.19	124	58	2	10	131	19	139	9e-30	115
tr:A4SV21_POLSQ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.63	95	44	1	20	113	25	119	9e-30	115
rs:WP_018730776	phosphoribosyl-AMP cyclohydrolase [Salinispora pacifica].	53.61	97	45	0	18	114	35	131	9e-30	115
rs:WP_005194801	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. NIPH 298].	53.61	97	44	1	18	113	8	104	9e-30	119
tr:R9L6W6_9BACL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	52.58	97	46	0	17	113	21	117	9e-30	118
rs:WP_024864781	hypothetical protein [Butyrivibrio sp. FCS014].	52.48	101	48	0	13	113	228	328	9e-30	121
rs:WP_024571940	phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis].	54.74	95	43	0	18	112	7	101	9e-30	117
rs:WP_047119397	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. YC-RL1].	57.89	95	40	0	18	112	25	119	9e-30	115
rs:WP_005291450	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. NIPH 2100].	53.61	97	44	1	18	113	8	104	9e-30	118
rs:WP_044445640	phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis].	54.74	95	43	0	18	112	7	101	9e-30	117
rs:WP_005248386	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. CIP 51.11].	50.93	108	51	2	18	123	10	117	9e-30	119
rs:WP_029874177	phosphoribosyl-AMP cyclohydrolase [Rhizobium leguminosarum].	49.57	117	57	1	17	131	23	139	9e-30	115
rs:WP_003579404	phosphoribosyl-AMP cyclohydrolase [Rhizobium leguminosarum].	49.19	124	58	2	10	131	19	139	9e-30	115
rs:WP_028033442	phosphoribosyl-AMP cyclohydrolase [Chelativorans sp. J32].	54.55	99	43	1	17	113	23	121	9e-30	115
rs:WP_046531391	phosphoribosyl-AMP cyclohydrolase [Candidatus Accumulibacter phosphatis].	52.04	98	46	1	17	113	13	110	9e-30	115
rs:WP_036645115	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. oral taxon 786].	52.58	97	46	0	17	113	13	109	9e-30	117
rs:WP_027096824	phosphoribosyl-AMP cyclohydrolase [Clostridium paraputrificum].	55.56	90	40	0	24	113	20	109	9e-30	114
tr:W6JYA6_9MICO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	56.84	95	41	0	18	112	11	105	9e-30	115
rs:WP_040081709	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. A053].	56.99	93	40	0	20	112	9	101	9e-30	117
rs:WP_021258718	phosphoribosyl-ATP diphosphatase [Paenibacillus alvei].	50.52	97	48	0	16	112	14	110	9e-30	118
rs:WP_004668390	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. CIP-A165].	53.61	97	44	1	18	113	8	104	1e-29	118
rs:WP_018205340	MULTISPECIES: hypothetical protein [unclassified Atribacteria].	46.43	112	59	1	16	126	8	119	1e-29	118
rs:WP_047242070	phosphoribosyl-ATP pyrophosphatase [Enterococcus cecorum].	47.41	116	59	1	13	126	2	117	1e-29	117
rs:WP_002300444	phosphoribosyl-AMP cyclohydrolase [Streptococcus mutans].	51.58	95	46	0	22	116	11	105	1e-29	114
rs:WP_039302373	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. IHB B 3415].	53.06	98	46	0	16	113	17	114	1e-29	118
rs:WP_028322972	phosphoribosyl-AMP cyclohydrolase [Desulfatiglans anilini].	54.90	102	44	2	18	117	3	104	1e-29	115
rs:WP_026853634	hypothetical protein [Geothrix fermentans].	52.94	102	45	2	11	112	1	99	1e-29	117
rs:WP_033133997	phosphoribosyl-ATP diphosphatase [Acinetobacter sp. MN12].	53.61	97	44	1	18	113	8	104	1e-29	118
rs:WP_026477333	phosphoribosyl-ATP pyrophosphatase [Alkaliphilus transvaalensis].	50.96	104	49	1	11	114	1	102	1e-29	118
rs:WP_012757552	phosphoribosyl-AMP cyclohydrolase [Rhizobium leguminosarum].	49.19	124	58	2	10	131	19	139	1e-29	115
rs:WP_003273586	phosphoribosyl-AMP cyclohydrolase [Ralstonia solanacearum].	46.73	107	56	1	16	121	7	113	1e-29	115
rs:WP_033923412	phosphoribosyl-AMP cyclohydrolase, partial [Sphingomonas sp. 37zxx].	53.06	98	46	0	19	116	13	110	1e-29	114
tr:C0FY71_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	43.88	139	65	2	2	127	209	347	1e-29	121
tr:C6J1M1_9BACL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	52.58	97	46	0	17	113	21	117	1e-29	118
rs:WP_013013901	phosphoribosyl-ATP pyrophosphatase [Meiothermus ruber].	49.50	101	51	0	13	113	1	101	1e-29	117
rs:WP_005278578	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. NIPH 1859].	53.61	97	44	1	18	113	8	104	1e-29	118
rs:WP_027460844	MULTISPECIES: imidazole glycerol phosphate synthase [Deinococcus].	51.82	110	52	1	18	126	12	121	1e-29	117
rs:WP_017870661	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Deinococcus].	53.54	99	46	0	14	112	3	101	1e-29	117
rs:WP_046348505	phosphoribosyl-AMP cyclohydrolase [Sphingomonas changbaiensis].	47.11	121	58	2	1	120	1	116	1e-29	115
rs:WP_007816604	phosphoribosyl-AMP cyclohydrolase [Rhizobium sp. CF142].	52.21	113	50	2	17	125	23	135	1e-29	115
rs:WP_026427770	phosphoribosyl-AMP cyclohydrolase [Actinomyces slackii].	54.08	98	45	0	15	112	6	103	1e-29	115
rs:WP_006201638	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium amorphae].	48.72	117	48	2	19	123	25	141	1e-29	115
rs:WP_017887197	hypothetical protein [Curtobacterium flaccumfaciens].	54.84	93	42	0	20	112	18	110	1e-29	115
rs:WP_017252222	phosphoribosyl-ATP pyrophosphatase [Brevibacillus brevis].	51.00	100	49	0	13	112	7	106	1e-29	117
rs:WP_042172010	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. FSL R7-0331].	52.08	96	46	0	18	113	12	107	1e-29	117
rs:WP_028733744	phosphoribosyl-AMP cyclohydrolase [Rhizobium leguminosarum].	49.57	117	57	1	17	131	23	139	1e-29	115
rs:WP_038692982	phosphoribosyl-ATP pyrophosphatase [Paenibacillus stellifer].	56.25	96	42	0	18	113	15	110	1e-29	118
rs:WP_043926639	phosphoribosyl-ATP pyrophosphatase [Bacillus licheniformis].	54.64	97	44	0	18	114	7	103	1e-29	117
rs:WP_004656193	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. NIPH 809].	53.61	97	44	1	18	113	8	104	1e-29	118
rs:WP_036701207	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. J14].	52.58	97	46	0	17	113	13	109	1e-29	117
rs:WP_019640599	phosphoribosyl-ATP pyrophosphatase [Paenibacillus fonticola].	53.12	96	45	0	18	113	22	117	1e-29	118
rs:WP_009655226	phosphoribosyl-ATP pyrophosphatase [Selenomonas sp. FOBRC6].	49.02	102	51	1	11	112	1	101	1e-29	118
rs:WP_013885705	phosphoribosyl-AMP cyclohydrolase [Flexistipes sinusarabici].	55.56	90	40	0	24	113	9	98	1e-29	114
rs:WP_020166905	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Methylotenera].	49.50	101	50	1	18	117	7	107	1e-29	115
sp:HIS3_RHIL3	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	49.57	117	57	1	17	131	23	139	1e-29	115
rs:WP_026512971	hypothetical protein [Butyrivibrio sp. LB2008].	52.48	101	48	0	13	113	225	325	1e-29	120
rs:WP_043501825	phosphoribosyl-AMP cyclohydrolase [Georgenia sp. SUBG003].	53.06	98	46	0	15	112	12	109	1e-29	115
rs:WP_037601036	phosphoribosyl-AMP cyclohydrolase [Streptococcus salivarius].	50.96	104	45	1	11	114	6	103	1e-29	114
rs:WP_008377139	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Enterococcus].	46.02	113	61	0	18	130	4	116	1e-29	117
rs:WP_015197358	phosphoribosyl-AMP cyclohydrolase [Calothrix parietina].	46.67	120	57	2	7	124	16	130	1e-29	116
rs:WP_018030087	phosphoribosyl-AMP cyclohydrolase [Streptococcus ferus].	51.46	103	44	1	11	113	6	102	1e-29	114
rs:WP_045784991	phosphoribosyl-AMP cyclohydrolase [Ralstonia mannitolilytica].	45.79	107	57	1	16	121	7	113	1e-29	115
rs:WP_035192635	phosphoribosyl-ATP pyrophosphatase [Bacillus azotoformans].	50.00	100	50	0	13	112	1	100	1e-29	117
rs:WP_027432998	MULTISPECIES: hypothetical protein [unclassified Lachnospiraceae].	55.10	98	44	0	16	113	221	318	1e-29	120
rs:WP_008838119	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium alhagi].	55.24	105	43	2	19	119	25	129	1e-29	115
rs:WP_028450361	phosphoribosyl-AMP cyclohydrolase [Chitinibacter tainanensis].	46.49	114	60	1	18	130	7	120	1e-29	115
rs:WP_025690802	phosphoribosyl-ATP pyrophosphatase [Paenibacillus zanthoxyli].	54.17	96	44	0	18	113	19	114	1e-29	118
rs:WP_013199071	phosphoribosyl-ATP diphosphatase [Acinetobacter oleivorans].	53.61	97	44	1	18	113	8	104	1e-29	118
rs:WP_034623447	phosphoribosyl-AMP cyclohydrolase [Cellulomonas sp. URHE0023].	54.74	95	43	0	18	112	17	111	1e-29	115
rs:WP_044928598	hypothetical protein [Roseburia inulinivorans].	43.88	139	65	2	2	127	196	334	1e-29	120
rs:WP_006466809	phosphoribosyl-AMP cyclohydrolase [Ochrobactrum intermedium].	54.29	105	44	2	19	119	23	127	1e-29	115
rs:WP_009523986	phosphoribosyl-AMP cyclohydrolase [Ralstonia sp. PBA].	47.17	106	55	1	16	120	7	112	1e-29	115
rs:WP_022675770	phosphoribosyl-AMP cyclohydrolase [Novosphingobium sp. B-7].	52.63	95	45	0	19	113	19	113	1e-29	115
rs:WP_036612096	hypothetical protein, partial [Oribacterium sp. P6A1].	49.50	101	51	0	12	112	5	105	1e-29	114
rs:WP_046792244	phosphoribosyl-AMP cyclohydrolase [Rhizobium sp. LC145].	47.86	117	59	1	17	131	22	138	1e-29	115
rs:WP_035404578	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. SJS].	51.52	99	48	0	14	112	2	100	1e-29	117
rs:WP_016542338	phosphoribosyl-AMP cyclohydrolase [Acinetobacter gyllenbergii].	53.61	97	44	1	18	113	8	104	1e-29	118
tr:C8WUY1_ALIAD	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	50.00	110	53	2	12	119	4	113	1e-29	118
rs:WP_037285831	phosphoribosyl-ATP pyrophosphatase [Saccharibacillus sacchari].	52.00	100	48	0	15	114	15	114	1e-29	118
rs:WP_041707332	phosphoribosyl-ATP pyrophosphatase [Alicyclobacillus acidocaldarius].	50.00	110	53	2	12	119	7	116	1e-29	118
tr:X1I1N6_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S15291 {ECO:0000313|EMBL:GAH63235.1}; Flags: Fragment;	51.02	98	48	0	16	113	3	100	1e-29	114
rs:WP_029195986	phosphoribosyl-ATP pyrophosphatase [Paenibacillus alginolyticus].	50.00	102	51	0	11	112	1	102	1e-29	117
rs:WP_033828481	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. KW-12].	48.08	104	54	0	11	114	1	104	1e-29	117
sp:HIS3_RHILW	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	49.57	117	57	1	17	131	23	139	1e-29	115
rs:WP_046865389	phosphoribosyl-AMP cyclohydrolase [Microvirga sp. JC119].	53.33	105	47	1	19	121	25	129	1e-29	115
rs:WP_022937394	hypothetical protein [Dielma fastidiosa].	53.19	94	44	0	24	117	11	104	1e-29	114
rs:WP_017964406	phosphoribosyl-AMP cyclohydrolase [Rhizobium leguminosarum].	49.57	117	57	1	17	131	23	139	1e-29	115
gpu:CP011770_1616	phosphoribosyl-AMP cyclohydrolase [Croceicoccus naphthovorans]	50.94	106	51	1	19	123	14	119	1e-29	114
rs:WP_018216330	phosphoribosyl-AMP cyclohydrolase [Salinispora pacifica].	53.61	97	45	0	18	114	35	131	1e-29	115
sp:HIS3_LISIN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	48.54	103	52	1	16	118	2	103	1e-29	114
rs:WP_010197871	phosphoribosyl-AMP cyclohydrolase [Psychrobacter sp. PAMC 21119].	53.54	99	45	1	16	113	8	106	1e-29	119
rs:WP_022495759	phosphoribosyl-AMP cyclohydrolase [Streptococcus salivarius CAG:79].	49.07	108	49	1	11	118	6	107	1e-29	114
rs:WP_005023099	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Acinetobacter].	52.58	97	45	1	18	113	10	106	1e-29	118
rs:WP_006804168	phosphoribosyl-ATP pyrophosphatase [Leptotrichia hofstadii].	50.52	97	48	0	18	114	6	102	1e-29	117
rs:WP_007629155	phosphoribosyl-AMP cyclohydrolase [Rhizobium sp. CCGE 510].	49.57	117	57	1	17	131	23	139	1e-29	115
sp:HIS3_RHIEC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	49.19	124	58	2	10	131	19	139	1e-29	115
rs:WP_034815258	phosphoribosyl-AMP cyclohydrolase [Exiguobacterium alkaliphilum].	49.00	100	51	0	18	117	10	109	1e-29	114
rs:WP_026651211	hypothetical protein [Butyrivibrio proteoclasticus].	57.29	96	41	0	18	113	236	331	1e-29	120
rs:WP_037102487	phosphoribosyl-AMP cyclohydrolase [Rhizobium alamii].	52.21	113	50	2	17	125	23	135	1e-29	115
rs:WP_036095060	phosphoribosyl-AMP cyclohydrolase [Listeria newyorkensis].	50.94	106	51	1	17	122	2	106	1e-29	114
tr:G2ZYB1_9RALS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	45.79	107	57	1	16	121	7	113	1e-29	115
rs:WP_007688801	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Sphingomonadaceae].	51.89	106	49	1	19	124	14	117	1e-29	114
rs:WP_010328717	phosphoribosyl-ATP pyrophosphatase [Bacillus vallismortis].	54.74	95	43	0	18	112	7	101	1e-29	117
rs:WP_018816798	phosphoribosyl-AMP cyclohydrolase [Salinispora pacifica].	53.61	97	45	0	18	114	35	131	1e-29	115
rs:WP_004054072	phosphoribosyl-AMP cyclohydrolase [Halococcus morrhuae].	54.17	96	44	0	18	113	10	105	1e-29	115
tr:U4T690_9GAMM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	53.54	99	45	1	16	113	9	107	1e-29	119
rs:WP_040641530	phosphoribosyl-AMP cyclohydrolase [Psychrobacter aquaticus].	53.54	99	45	1	16	113	8	106	1e-29	119
rs:WP_009147694	phosphoribosyl-AMP cyclohydrolase [Thiorhodovibrio sp. 970].	49.09	110	49	2	9	117	9	112	1e-29	115
rs:WP_023009626	hypothetical protein [Marinobacter sp. EVN1].	54.72	106	46	1	19	122	36	141	1e-29	116
rs:WP_003572988	phosphoribosyl-AMP cyclohydrolase [Rhizobium leguminosarum].	49.19	124	58	2	10	131	19	139	1e-29	115
tr:F3P0S9_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	58.62	87	36	0	26	112	1	87	1e-29	114
rs:WP_006906193	hypothetical protein [Shuttleworthia satelles].	49.12	114	55	2	16	126	24	137	1e-29	115
rs:WP_044109442	phosphoribosyl-ATP pyrophosphatase [Prevotella brevis].	54.44	90	41	0	23	112	12	101	1e-29	117
rs:WP_047330433	phosphoribosyl-AMP cyclohydrolase [Mycobacterium sp. EPa45].	54.74	95	43	0	18	112	11	105	1e-29	114
rs:WP_040289843	phosphoribosyl-ATP pyrophosphatase [Alicyclobacillus hesperidum].	48.25	114	58	1	8	120	3	116	1e-29	118
rs:WP_010529312	phosphoribosyl-ATP pyrophosphatase [Lentibacillus jeotgali].	50.00	106	53	0	12	117	3	108	1e-29	117
rs:WP_047343012	phosphoribosyl-ATP pyrophosphatase [Enterococcus cecorum].	46.55	116	60	1	13	126	2	117	1e-29	117
rs:WP_027086343	phosphoribosyl-ATP pyrophosphatase [Cohnella panacarvi].	53.00	100	47	0	18	117	14	113	1e-29	117
rs:WP_038344768	phosphoribosyl-ATP diphosphatase [Acinetobacter sp. A47].	53.61	97	44	1	18	113	8	104	1e-29	118
rs:WP_018165708	phosphoribosyl-AMP cyclohydrolase [Streptococcus henryi].	50.00	104	46	1	11	114	6	103	1e-29	114
sp:HIS3_LISW6	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	48.54	103	52	1	17	119	3	104	1e-29	114
rs:WP_008526208	phosphoribosyl-AMP cyclohydrolase [Rhizobium sp. Pop5].	49.57	117	57	1	17	131	23	139	1e-29	115
rs:WP_015391632	phosphoribosyl-AMP cyclohydrolase [Clostridium saccharoperbutylacetonicum].	50.00	106	47	1	11	116	10	109	1e-29	114
rs:WP_038468190	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. PAMC25486].	52.63	95	45	0	18	112	30	124	1e-29	115
rs:WP_019836068	phosphoribosyl-ATP diphosphatase [Acinetobacter sp. MDS7A].	53.61	97	44	1	18	113	10	106	1e-29	118
rs:WP_010747556	phosphoribosyl-ATP diphosphatase [Enterococcus casseliflavus].	46.02	113	61	0	18	130	4	116	1e-29	117
rs:WP_006159660	phosphoribosyl-AMP cyclohydrolase [Cupriavidus basilensis].	47.66	107	55	1	16	121	7	113	1e-29	115
rs:WP_018391295	phosphoribosyl-AMP cyclohydrolase [Ancylobacter sp. FA202].	52.29	109	45	1	19	120	24	132	1e-29	115
rs:WP_025332690	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sabinae].	50.00	106	53	0	18	123	19	124	1e-29	117
rs:WP_006802750	phosphoribosyl-ATP pyrophosphatase [Helicobacter winghamensis].	50.00	94	47	0	23	116	14	107	1e-29	117
rs:WP_044927658	MULTISPECIES: imidazole glycerol phosphate synthase [Butyrivibrio].	49.02	102	52	0	13	114	5	106	1e-29	117
rs:WP_030172956	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Actinomycetales].	57.89	95	40	0	18	112	11	105	1e-29	114
rs:WP_046478612	phosphoribosyl-AMP cyclohydrolase [Filomicrobium sp. W].	53.00	100	45	1	19	116	22	121	1e-29	115
rs:WP_021239091	phosphoribosyl-AMP cyclohydrolase [Sphingobium quisquiliarum].	51.46	103	50	0	15	117	10	112	1e-29	114
rs:WP_004802338	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. CIP 56.2].	53.61	97	44	1	18	113	8	104	1e-29	118
rs:WP_010836189	phosphoribosyl-AMP cyclohydrolase [Rhodococcus rhodnii].	51.55	97	47	0	16	112	11	107	2e-29	114
rs:WP_046331028	phosphoribosyl-AMP cyclohydrolase [Polynucleobacter necessarius].	49.04	104	52	1	17	119	19	122	2e-29	115
rs:WP_028000203	phosphoribosyl-AMP cyclohydrolase [Sinorhizobium arboris].	53.70	108	47	2	17	121	22	129	2e-29	115
rs:WP_019782390	phosphoribosyl-AMP cyclohydrolase [Streptococcus sobrinus].	51.43	105	45	1	10	114	5	103	2e-29	114
rs:WP_010534452	phosphoribosyl-AMP cyclohydrolase [Brachybacterium squillarum].	53.68	95	44	0	18	112	16	110	2e-29	114
rs:WP_010762896	phosphoribosyl-AMP cyclohydrolase [Enterococcus haemoperoxidus].	50.54	93	46	0	24	116	8	100	2e-29	114
rs:WP_029205378	phosphoribosyl-AMP cyclohydrolase [alpha proteobacterium SCGC AB-629-F11].	48.72	117	55	3	4	119	14	126	2e-29	115
rs:WP_025392465	hypothetical protein [Desulfurella acetivorans].	48.48	99	51	0	15	113	4	102	2e-29	118
rs:WP_045223098	phosphoribosyl-AMP cyclohydrolase [Desulfonatronum thioautotrophicum].	52.78	108	50	1	24	130	10	117	2e-29	114
rs:WP_022364822	phosphoribosyl-AMP cyclohydrolase [Clostridium sp. CAG:505].	50.00	100	50	0	13	112	2	101	2e-29	117
rs:WP_043669646	phosphoribosyl-AMP cyclohydrolase [Clavibacter michiganensis].	53.19	94	44	0	19	112	18	111	2e-29	114
rs:WP_013909387	phosphoribosyl-AMP cyclohydrolase [Thermodesulfobacterium geofontis].	49.50	101	51	0	24	124	12	112	2e-29	114
gpu:CP007501_111	Phosphoribosyl-AMP cyclohydrolase [Polynucleobacter necessarius subsp. asymbioticus]	49.04	104	52	1	17	119	33	136	2e-29	115
rs:WP_025701923	phosphoribosyl-ATP pyrophosphatase [Paenibacillus forsythiae].	54.17	96	44	0	18	113	17	112	2e-29	117
rs:WP_027974510	phosphoribosyl-AMP cyclohydrolase [Streptococcus porci].	49.51	103	46	1	11	113	6	102	2e-29	114
rs:WP_022689397	phosphoribosyl-AMP cyclohydrolase [Sphingomonas-like bacterium B12].	46.40	125	61	2	1	125	1	119	2e-29	114
rs:WP_029166113	phosphoribosyl-ATP pyrophosphatase [Aminiphilus circumscriptus].	54.08	98	45	0	17	114	8	105	2e-29	117
rs:WP_034218691	imidazole glycerol phosphate synthase [Lachnoclostridium phytofermentans].	56.82	88	38	0	26	113	1	88	2e-29	116
rs:WP_034346188	phosphoribosyl-ATP diphosphatase [Helicobacter trogontum].	51.06	94	46	0	24	117	12	105	2e-29	117
rs:WP_014545150	phosphoribosyl-AMP cyclohydrolase [Fibrobacter succinogenes].	55.10	98	42	1	18	113	14	111	2e-29	114
rs:WP_008870156	phosphoribosyl-AMP cyclohydrolase [Desulfonatronospira thiodismutans].	53.27	107	43	2	12	117	4	104	2e-29	114
rs:WP_027126795	phosphoribosyl-ATP pyrophosphatase [Gelidibacter mesophilus].	51.58	95	46	0	17	111	2	96	2e-29	116
rs:WP_039205816	phosphoribosyl-ATP pyrophosphatase [Anaerovibrio lipolyticus].	56.44	101	42	2	13	112	2	101	2e-29	117
sp:HIS3_PELCD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	55.56	99	43	1	23	120	10	108	2e-29	114
rs:WP_000073503	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	53.61	97	44	1	18	113	8	104	2e-29	118
rs:WP_015789525	phosphoribosyl-AMP cyclohydrolase [Halorhabdus utahensis].	48.15	108	56	0	10	117	15	122	2e-29	115
tr:W7ZY69_9BACI	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	52.58	97	46	0	16	112	2	98	2e-29	117
sp:HIS3_STRTD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.00	108	48	1	11	118	6	107	2e-29	114
rs:WP_008474661	phosphoribosyl-ATP pyrophosphatase [Nitrolancea hollandica].	47.47	99	52	0	14	112	6	104	2e-29	117
rs:WP_000073505	hypothetical protein [Acinetobacter baumannii].	53.61	97	44	1	18	113	8	104	2e-29	118
rs:WP_019173394	phosphoribosyl-AMP cyclohydrolase [Pseudaminobacter salicylatoxidans].	51.75	114	51	2	17	126	23	136	2e-29	115
rs:WP_043734558	imidazole glycerol phosphate synthase [Lactococcus lactis].	53.61	97	45	0	20	116	5	101	2e-29	117
rs:WP_040766093	phosphoribosyl-ATP diphosphatase [Sulfurimonas sp. AST-10].	54.84	93	42	0	25	117	15	107	2e-29	117
rs:WP_047183256	phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis].	53.68	95	44	0	18	112	7	101	2e-29	117
rs:WP_033888925	phosphoribosyl-AMP cyclohydrolase, partial [Pseudomonas aeruginosa].	57.45	94	39	1	18	110	8	101	2e-29	114
rs:WP_019586322	phosphoribosyl-ATP pyrophosphatase [Deinococcus apachensis].	55.21	96	43	0	18	113	7	102	2e-29	117
rs:WP_031437129	phosphoribosyl-AMP cyclohydrolase [Methylobacter tundripaludum].	46.49	114	60	1	18	130	9	122	2e-29	114
tr:T0JML9_9HELI	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	54.84	93	42	0	25	117	17	109	2e-29	117
rs:WP_005218575	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. ANC 3862].	53.61	97	44	1	18	113	8	104	2e-29	118
rs:WP_000073502	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	53.61	97	44	1	18	113	8	104	2e-29	118
rs:WP_018450024	phosphoribosyl-ATP pyrophosphatase [Leptotrichia shahii].	48.51	101	52	0	14	114	2	102	2e-29	117
rs:WP_000073504	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	53.61	97	44	1	18	113	8	104	2e-29	117
rs:WP_002959132	phosphoribosyl-AMP cyclohydrolase [Streptococcus sobrinus].	54.26	94	43	0	21	114	10	103	2e-29	114
rs:WP_010168639	phosphoribosyl-ATP pyrophosphatase [Epulopiscium sp. 'N.t. morphotype B'].	50.96	104	50	1	18	120	2	105	2e-29	117
rs:WP_026520685	hypothetical protein [Butyrivibrio sp. VCB2001].	49.57	115	56	1	1	113	218	332	2e-29	120
rs:WP_019769247	phosphoribosyl-AMP cyclohydrolase [Streptococcus sobrinus].	51.43	105	45	1	10	114	5	103	2e-29	114
rs:WP_046513814	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. SA1-12].	50.00	96	48	0	17	112	4	99	2e-29	117
tr:J9HCX0_9BACL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	50.91	110	48	1	11	120	1	104	2e-29	117
rs:WP_004659252	phosphoribosyl-ATP diphosphatase [Acinetobacter sp. NIPH 236].	53.61	97	44	1	18	113	8	104	2e-29	117
rs:WP_021197520	phosphoribosyl-AMP cyclohydrolase [Ralstonia sp. AU12-08].	45.79	107	57	1	16	121	7	113	2e-29	115
rs:WP_022288888	histidine biosynthesis bifunctional protein HisIE [Oscillibacter sp. CAG:155].	53.61	97	45	0	18	114	3	99	2e-29	117
rs:WP_036690054	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. FSL R7-269].	52.04	98	47	0	16	113	17	114	2e-29	117
rs:WP_003870633	phosphoribosyl-ATP pyrophosphatase [Thermoanaerobacter ethanolicus].	50.00	100	50	0	14	113	3	102	2e-29	117
rs:WP_047338387	phosphoribosyl-ATP pyrophosphatase [Enterococcus cecorum].	47.41	116	59	1	13	126	2	117	2e-29	117
rs:WP_027416296	phosphoribosyl-ATP pyrophosphatase [Aneurinibacillus terranovensis].	51.00	100	49	0	13	112	1	100	2e-29	117
rs:WP_046782000	imidazole glycerol phosphate synthase [Lactococcus lactis].	53.61	97	45	0	20	116	5	101	2e-29	117
rs:WP_021896751	histidine biosynthesis protein HisIE [Prevotella sp. CAG:924].	52.94	102	42	2	11	112	3	98	2e-29	117
rs:WP_020878959	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio sp. X2].	51.82	110	51	2	23	130	9	118	2e-29	114
rs:WP_027406362	phosphoribosyl-ATP pyrophosphatase [Anaerovibrio sp. RM50].	56.44	101	42	2	13	112	2	101	2e-29	117
rs:WP_035261686	phosphoribosyl-AMP cyclohydrolase [Desulfonatronum lacustre].	56.12	98	42	1	24	120	10	107	2e-29	114
sp:HIS2_BACHD	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	51.52	99	48	0	18	116	6	104	2e-29	116
rs:WP_011835166	phosphoribosyl-ATP pyrophosphatase [Lactococcus lactis].	53.61	97	45	0	20	116	5	101	2e-29	117
rs:WP_041484986	phosphoribosyl-AMP cyclohydrolase [beta proteobacterium CB].	50.50	101	49	1	20	119	15	115	2e-29	114
rs:WP_041061785	phosphoribosyl-ATP pyrophosphatase [Jeotgalibacillus campisalis].	46.00	100	54	0	13	112	1	100	2e-29	117
rs:WP_004803315	phosphoribosyl-ATP diphosphatase [Eggerthia catenaformis].	53.85	91	42	0	24	114	10	100	2e-29	117
rs:WP_015667709	phosphoribosyl-AMP cyclohydrolase [Bradyrhizobium oligotrophicum].	51.52	99	48	0	19	117	17	115	2e-29	114
tr:M1T0Q0_9PROT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	50.50	101	49	1	20	119	24	124	2e-29	114
rs:WP_004442257	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Rhizobium/Agrobacterium group].	52.99	117	49	3	19	129	24	140	2e-29	115
rs:WP_022607115	phosphoribosyl-AMP cyclohydrolase [Rubidibacter lacunae].	56.31	103	43	1	19	119	23	125	2e-29	115
rs:WP_037170208	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Rhizobium].	48.72	117	58	1	17	131	22	138	2e-29	115
rs:WP_010651831	phosphoribosyl-ATP pyrophosphatase [Oceanobacillus massiliensis].	49.04	104	53	0	11	114	1	104	2e-29	116
rs:WP_009821374	phosphoribosyl-AMP cyclohydrolase [Sphingomonas sp. SKA58].	54.08	98	45	0	19	116	14	111	2e-29	114
rs:WP_022123562	hypothetical protein [Clostridium sp. CAG:510].	51.96	102	49	0	12	113	233	334	2e-29	120
rs:WP_025873381	phosphoribosyl-AMP cyclohydrolase [Enterococcus sp. TR].	52.69	93	44	0	24	116	8	100	2e-29	113
rs:WP_026654862	hypothetical protein [Butyrivibrio sp. AE3003].	51.49	101	49	0	13	113	225	325	2e-29	120
rs:WP_029199474	phosphoribosyl-AMP cyclohydrolase [Oribacterium sp. NK2B42].	49.50	101	51	0	12	112	5	105	2e-29	114
rs:WP_018363558	phosphoribosyl-AMP cyclohydrolase [Streptococcus caballi].	53.19	94	44	0	21	114	10	103	2e-29	114
rs:WP_035039770	hypothetical protein, partial [Catonella morbi].	50.00	100	50	0	13	112	2	101	2e-29	113
rs:WP_023593070	phosphoribosyl-AMP cyclohydrolase [Zymomonas mobilis].	52.00	100	48	0	20	119	15	114	2e-29	114
rs:WP_028584483	phosphoribosyl-AMP cyclohydrolase [Desulfobulbus mediterraneus].	51.55	97	46	1	21	116	9	105	2e-29	114
rs:WP_015215521	phosphoribosyl-AMP cyclohydrolase [Anabaena cylindrica].	52.53	99	46	1	18	115	26	124	2e-29	117
rs:WP_029551113	phosphoribosyl-ATP pyrophosphatase [Thermocrinis sp. GBS].	52.53	99	46	1	16	113	9	107	2e-29	116
rs:WP_016174662	phosphoribosyl-ATP diphosphatase [Enterococcus saccharolyticus].	44.54	119	64	1	14	130	2	120	2e-29	116
rs:WP_035870669	phosphoribosyl-AMP cyclohydrolase [Cupriavidus sp. SK-3].	46.73	107	56	1	16	121	7	113	2e-29	114
rs:WP_027396036	phosphoribosyl-ATP pyrophosphatase [Anaerovibrio lipolyticus].	56.44	101	42	2	13	112	2	101	2e-29	117
rs:WP_024122977	phosphoribosyl-ATP pyrophosphatase [Bacillus mojavensis].	54.74	95	43	0	18	112	7	101	2e-29	116
rs:WP_038675800	phosphoribosyl-AMP cyclohydrolase [Streptococcus salivarius].	49.07	108	49	1	11	118	6	107	2e-29	114
rs:WP_044946406	hypothetical protein [Lachnospiraceae bacterium NC2004].	50.00	106	51	1	9	114	212	315	2e-29	120
sp:HIS3_SACD2	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.00	108	53	1	24	130	16	123	2e-29	114
rs:WP_022967782	phosphoribosyl-AMP cyclohydrolase [Arenimonas oryziterrae].	55.00	100	44	1	14	112	5	104	2e-29	116
rs:WP_009377176	phosphoribosyl-AMP cyclohydrolase [Brevibacterium casei].	54.74	95	43	0	18	112	17	111	2e-29	114
rs:WP_002890736	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptococcus].	49.07	108	49	1	11	118	6	107	2e-29	114
rs:WP_022773994	imidazole glycerol phosphate synthase [Butyrivibrio sp. AE2015].	55.21	96	43	0	18	113	207	302	2e-29	120
rs:WP_021802894	histidine biosynthesis bifunctional protein hisIE [Clostridium intestinale].	48.11	106	54	1	13	117	2	107	2e-29	113
rs:WP_022782755	imidazole glycerol phosphate synthase [Lachnospiraceae bacterium NK4A179].	52.48	101	48	0	16	116	233	333	2e-29	120
rs:WP_033167586	imidazole glycerol phosphate synthase [Clostridium sp. KNHs205].	53.93	89	41	0	25	113	1	89	2e-29	116
rs:WP_011676145	phosphoribosyl-ATP pyrophosphatase [Lactococcus lactis].	53.61	97	45	0	20	116	5	101	2e-29	116
rs:WP_003644681	phosphoribosyl-AMP cyclohydrolase [Lactobacillus plantarum].	53.19	94	44	0	24	117	10	103	2e-29	113
sp:HIS3_BACCR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	55.56	90	40	0	24	113	8	97	2e-29	113
rs:WP_016993559	phosphoribosyl-ATP pyrophosphatase [Lysinibacillus boronitolerans].	43.75	112	63	0	17	128	4	115	2e-29	116
rs:WP_006890814	phosphoribosyl-AMP cyclohydrolase [Methylobacter tundripaludum].	46.49	114	60	1	18	130	9	122	2e-29	114
rs:WP_003271443	phosphoribosyl-AMP cyclohydrolase [Ralstonia solanacearum].	46.73	107	56	1	16	121	7	113	2e-29	114
rs:WP_044159348	phosphoribosyl-ATP pyrophosphatase [Salinibacillus aidingensis].	54.74	95	43	0	18	112	7	101	2e-29	116
rs:WP_014572623	phosphoribosyl-ATP pyrophosphatase [Lactococcus lactis].	53.61	97	45	0	20	116	5	101	2e-29	116
tr:C3XEW8_9HELI	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	48.00	100	52	0	18	117	12	111	2e-29	117
sp:HIS3_GEOUR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.04	98	46	1	23	119	10	107	2e-29	114
rs:WP_022682618	phosphoribosyl-AMP cyclohydrolase [Sphingobium sp. YL23].	49.55	111	54	1	15	125	10	118	2e-29	114
rs:WP_045647224	phosphoribosyl-AMP cyclohydrolase [Hoeflea sp. BRH_c9].	53.85	104	45	2	19	119	24	127	2e-29	115
rs:WP_035152362	hypothetical protein [Clostridium tetanomorphum].	49.48	97	49	0	20	116	12	108	2e-29	116
rs:WP_046542741	phosphoribosyl-AMP cyclohydrolase [Trichodesmium thiebautii].	53.27	107	48	1	19	123	23	129	2e-29	115
rs:WP_021067264	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Exiguobacterium].	49.00	100	51	0	18	117	10	109	2e-29	113
rs:WP_021972146	phosphoribosyl-AMP cyclohydrolase [Eubacterium sp. CAG:180].	47.66	107	53	1	11	117	1	104	2e-29	113
rs:WP_015509108	phosphoribosyl-ATP diphosphatase [Enterococcus casseliflavus].	46.02	113	61	0	18	130	4	116	2e-29	116
rs:WP_005355459	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Clostridiales].	50.49	103	48	1	11	113	1	100	2e-29	113
rs:WP_012742531	imidazole glycerol phosphate synthase [Eubacterium rectale].	51.96	102	49	0	12	113	223	324	2e-29	120
rs:WP_004227997	phosphoribosyl-ATP pyrophosphatase [Lysinibacillus fusiformis].	42.86	112	64	0	17	128	4	115	2e-29	116
rs:WP_026697740	phosphoribosyl-ATP pyrophosphatase [Bacillus chagannorensis].	50.50	101	50	0	13	113	1	101	2e-29	116
rs:WP_043061731	phosphoribosyl-AMP cyclohydrolase [Ochrobactrum anthropi].	52.25	111	51	1	19	127	23	133	2e-29	114
sp:HIS3_LACPL	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.19	94	44	0	24	117	10	103	2e-29	113
rs:WP_021746601	phosphoribosyl-ATP diphosphatase [Leptotrichia wadei].	49.48	97	49	0	18	114	6	102	2e-29	116
rs:WP_006930073	phosphoribosyl-AMP cyclohydrolase [Caldithrix abyssi].	56.67	90	39	0	24	113	10	99	2e-29	116
rs:WP_029648472	phosphoribosyl-AMP cyclohydrolase [Methylocystis sp. SB2].	51.35	111	51	2	19	126	17	127	2e-29	114
rs:WP_012772167	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. JDR-2].	51.43	105	50	1	18	121	9	113	2e-29	117
rs:WP_022767171	imidazole glycerol phosphate synthase [Butyrivibrio sp. NC2007].	49.57	115	56	1	1	113	218	332	3e-29	120
rs:WP_005217550	phosphoribosyl-ATP pyrophosphatase [Helicobacter bilis].	48.00	100	52	0	18	117	6	105	3e-29	117
rs:WP_044383853	phosphoribosyl-AMP cyclohydrolase [Marinobacter excellens].	51.79	112	52	1	19	128	36	147	3e-29	115
rs:WP_008595957	phosphoribosyl-AMP cyclohydrolase [Nitratireductor pacificus].	57.73	97	39	1	19	113	25	121	3e-29	114
rs:WP_003523396	phosphoribosyl-AMP cyclohydrolase [Agrobacterium tumefaciens].	52.14	117	50	3	19	129	24	140	3e-29	114
tr:U2ARC8_9CLOT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	50.00	118	53	1	13	130	224	335	3e-29	120
rs:WP_010676571	phosphoribosyl-ATP pyrophosphatase [Bacillus timonensis].	48.00	100	52	0	13	112	1	100	3e-29	116
tr:C4V2J2_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	50.00	102	50	1	11	112	2	102	3e-29	117
rs:WP_035541969	phosphoribosyl-ATP pyrophosphatase [Halobacillus sp. BBL2006].	51.58	95	46	0	18	112	6	100	3e-29	116
rs:WP_035386293	phosphoribosyl-AMP cyclohydrolase [Exiguobacterium sp. S17].	48.00	100	52	0	18	117	10	109	3e-29	113
rs:WP_019787772	phosphoribosyl-AMP cyclohydrolase [Streptococcus sobrinus].	53.54	99	45	1	17	114	5	103	3e-29	113
rs:WP_027876525	imidazole glycerol phosphate synthase [Meiothermus cerbereus].	49.50	101	51	0	13	113	1	101	3e-29	116
rs:WP_040572455	phosphoribosyl-ATP pyrophosphatase [Selenomonas flueggei].	50.00	102	50	1	11	112	1	101	3e-29	117
rs:WP_043446348	phosphoribosyl-AMP cyclohydrolase, partial [Arthrobacter sp. L77].	56.84	95	41	0	18	112	5	99	3e-29	114
rs:WP_014866159	phosphoribosyl-AMP cyclohydrolase [Methanoculleus bourgensis].	55.32	94	42	0	24	117	8	101	3e-29	114
rs:WP_015825770	phosphoribosyl-AMP cyclohydrolase [Lactobacillus plantarum].	52.63	95	45	0	23	117	9	103	3e-29	113
rs:WP_041135224	phosphoribosyl-ATP diphosphatase [Sulfurovum sp. AS07-7].	51.85	108	48	2	19	126	6	109	3e-29	116
rs:WP_041758072	phosphoribosyl-AMP cyclohydrolase [Psychrobacter arcticus].	52.53	99	46	1	16	113	8	106	3e-29	118
rs:WP_035660940	phosphoribosyl-ATP pyrophosphatase [Bacillus akibai].	49.07	108	54	1	18	124	6	113	3e-29	116
sp:HIS3_CUPPJ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	48.60	107	54	1	16	121	7	113	3e-29	114
rs:WP_022089571	phosphoribosyl-ATP diphosphatase [Eubacterium sp. CAG:156].	51.43	105	49	1	9	113	217	319	3e-29	119
rs:WP_011514609	phosphoribosyl-AMP cyclohydrolase [Psychrobacter cryohalolentis].	52.53	99	46	1	16	113	8	106	3e-29	118
rs:WP_028547082	phosphoribosyl-ATP pyrophosphatase [Paenibacillus taiwanensis].	52.58	97	46	0	17	113	25	121	3e-29	117
sp:HIS3_GEOMG	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.04	98	46	1	23	119	10	107	3e-29	114
tr:Q4FQ62_PSYA2	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	52.53	99	46	1	16	113	9	107	3e-29	118
rs:WP_044254406	phosphoribosyl-AMP cyclohydrolase, partial [Isosphaera pallida].	50.86	116	54	3	19	131	25	140	3e-29	114
rs:WP_024322673	phosphoribosyl-AMP cyclohydrolase [Rhizobium leguminosarum].	49.57	117	57	1	17	131	23	139	3e-29	114
tr:K9D2P8_9FIRM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	46.90	113	59	1	6	117	8	120	3e-29	114
rs:WP_018832752	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Salinispora].	52.58	97	46	0	18	114	35	131	3e-29	114
rs:WP_026306414	phosphoribosyl-AMP cyclohydrolase [Smaragdicoccus niigatensis].	55.79	95	42	0	18	112	5	99	3e-29	113
rs:WP_017228819	phosphoribosyl-AMP cyclohydrolase [Cupriavidus basilensis].	46.73	107	56	1	16	121	7	113	3e-29	114
sp:HIS3_OCHA4	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	56.00	100	42	1	19	116	23	122	3e-29	114
rs:WP_041390715	phosphoribosyl-AMP cyclohydrolase [Sphingobium chlorophenolicum].	49.09	110	54	1	15	124	10	117	3e-29	114
rs:WP_044570803	phosphoribosyl-AMP cyclohydrolase [Arthrobacter sp. A3].	54.74	95	43	0	18	112	30	124	3e-29	114
rs:WP_045773247	phosphoribosyl-AMP cyclohydrolase [Streptococcus sanguinis].	52.04	98	47	0	21	118	10	107	3e-29	113
rs:WP_026518918	hypothetical protein [Butyrivibrio sp. FCS006].	49.57	115	56	1	1	113	218	332	3e-29	119
rs:WP_020498281	hypothetical protein [Sciscionella marina].	58.06	93	39	0	24	116	13	105	3e-29	113
tr:B1XSV4_POLNS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	46.90	113	55	2	2	113	14	122	3e-29	114
rs:WP_005111201	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mycobacterium chelonae group].	54.74	95	43	0	18	112	12	106	3e-29	113
rs:WP_018379066	phosphoribosyl-AMP cyclohydrolase [Streptococcus ovis].	52.13	94	45	0	21	114	10	103	3e-29	113
rs:WP_040664487	phosphoribosyl-ATP pyrophosphatase [Nafulsella turpanensis].	51.49	101	43	1	12	112	16	110	3e-29	116
rs:WP_027009244	phosphoribosyl-AMP cyclohydrolase [Conchiformibius kuhniae].	47.46	118	61	1	15	131	5	122	3e-29	114
rs:WP_039075397	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. MSP13].	53.68	95	44	0	18	112	7	101	3e-29	116
rs:WP_022443918	phosphoribosyl-AMP cyclohydrolase [Sutterella sp. CAG:351].	46.96	115	59	2	18	130	9	123	3e-29	114
rs:WP_020819940	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Sphingobium].	51.89	106	49	1	19	124	14	117	3e-29	114
rs:WP_010660104	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Ochrobactrum].	56.00	100	42	1	19	116	23	122	3e-29	114
rs:WP_020444412	phosphoribosyl-AMP cyclohydrolase [Psychrobacter sp. G].	52.53	99	46	1	16	113	8	106	3e-29	117
rs:WP_023856355	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillus].	53.68	95	44	0	18	112	7	101	3e-29	116
rs:WP_036021995	phosphoribosyl-AMP cyclohydrolase [Leptolyngbya sp. PCC 7375].	55.34	103	44	1	19	119	23	125	3e-29	115
rs:WP_007050235	phosphoribosyl-ATP pyrophosphatase [Anaerofustis stercorihominis].	46.15	104	54	1	11	114	1	102	3e-29	116
rs:WP_003559610	phosphoribosyl-AMP cyclohydrolase [Rhizobium leguminosarum].	48.39	124	59	2	10	131	19	139	3e-29	114
rs:WP_034386901	imidazole glycerol phosphate synthase [Deinococcus sp. YIM 77859].	55.21	96	43	0	18	113	7	102	3e-29	116
rs:WP_031396541	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Sphingomonas].	51.52	99	48	0	19	117	14	112	3e-29	113
rs:WP_017391368	phosphoribosyl-ATP diphosphatase [Acinetobacter calcoaceticus].	52.58	97	45	1	18	113	8	104	3e-29	117
rs:WP_003642718	phosphoribosyl-AMP cyclohydrolase [Lactobacillus plantarum].	53.19	94	44	0	24	117	10	103	3e-29	113
tr:F6EYG9_SPHCR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216}; Flags: Precursor;	49.09	110	54	1	15	124	20	127	3e-29	114
rs:WP_023838309	phosphoribosyl-AMP cyclohydrolase [Blastomonas sp. CACIA14H2].	51.28	117	52	3	9	123	7	120	3e-29	113
rs:WP_019265072	phosphoribosyl-AMP cyclohydrolase [Methanobrevibacter smithii].	52.63	95	45	0	19	113	8	102	3e-29	114
rs:WP_016653214	phosphoribosyl-AMP cyclohydrolase [Acinetobacter sp. NIPH 2036].	52.58	97	45	1	18	113	8	104	3e-29	117
rs:WP_039230781	phosphoribosyl-ATP pyrophosphatase [Bacillus thermotolerans].	43.33	120	67	1	11	129	1	120	3e-29	116
rs:WP_041514158	phosphoribosyl-AMP cyclohydrolase [Nitrosospira sp. NpAV].	43.86	114	63	1	16	128	7	120	3e-29	114
rs:WP_026685805	phosphoribosyl-AMP cyclohydrolase [Azovibrio restrictus].	51.02	98	47	1	17	113	14	111	3e-29	114
rs:WP_007083452	phosphoribosyl-AMP cyclohydrolase [Bacillus bataviensis].	53.12	96	45	0	17	112	2	97	3e-29	115
rs:WP_004227281	phosphoribosyl-AMP cyclohydrolase [Streptococcus criceti].	56.04	91	40	0	24	114	13	103	3e-29	113
rs:WP_017960562	phosphoribosyl-AMP cyclohydrolase [Rhizobium leguminosarum].	49.57	117	57	1	17	131	23	139	3e-29	114
sp:HIS3_RHIME	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.44	113	52	2	17	125	22	134	3e-29	114
rs:WP_027208378	hypothetical protein [Butyrivibrio hungatei].	51.49	101	49	0	13	113	225	325	3e-29	119
rs:WP_026666783	hypothetical protein [Butyrivibrio sp. AE2005].	51.49	101	49	0	13	113	225	325	3e-29	119
sp:HIS3_CLOBA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.22	90	43	0	24	113	17	106	4e-29	113
rs:WP_045528163	phosphoribosyl-AMP cyclohydrolase [Clavibacter michiganensis].	54.26	94	43	0	19	112	18	111	4e-29	114
rs:WP_026944183	phosphoribosyl-ATP diphosphatase [Helicobacter rodentium].	52.69	93	44	0	24	116	15	107	4e-29	116
rs:WP_015306878	phosphoribosyl-AMP cyclohydrolase [Mycobacterium smegmatis].	53.61	97	45	0	16	112	9	105	4e-29	113
rs:WP_005381537	phosphoribosyl-AMP cyclohydrolase [Veillonella atypica].	53.54	99	45	1	20	117	5	103	4e-29	113
rs:WP_042705822	phosphoribosyl-AMP cyclohydrolase [Methanomicrobium mobile].	50.00	102	51	0	16	117	5	106	4e-29	113
rs:WP_007193958	phosphoribosyl-AMP cyclohydrolase [Thiocapsa marina].	52.04	98	46	1	17	113	8	105	4e-29	114
rs:WP_019868452	phosphoribosyl-AMP cyclohydrolase [Methylovulum miyakonense].	43.86	114	63	1	18	130	7	120	4e-29	114
rs:WP_047069706	phosphoribosyl-ATP pyrophosphatase [Brevibacillus formosus].	49.51	103	52	0	10	112	4	106	4e-29	116
rs:WP_036644203	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. FSL R5-808].	51.52	99	48	0	18	116	18	116	4e-29	116
rs:WP_016404521	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [Clostridium sp. CAG:1013].	53.40	103	48	0	11	113	247	349	4e-29	119
rs:WP_013829072	phosphoribosyl-AMP cyclohydrolase [Mycobacterium sp. JDM601].	56.84	95	41	0	18	112	14	108	4e-29	113
rs:WP_034580766	phosphoribosyl-ATP diphosphatase [Helicobacter bilis].	48.00	100	52	0	18	117	6	105	4e-29	116
rs:WP_006207526	phosphoribosyl-ATP pyrophosphatase [Paenibacillus vortex].	51.52	99	48	0	18	116	18	116	4e-29	116
tr:F5X295_STRPX	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	57.14	91	39	0	24	114	15	105	4e-29	113
rs:WP_034329043	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. FJAT-14578].	49.00	100	51	0	13	112	2	101	4e-29	116
tr:N2BHX0_9HELI	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	48.00	100	52	0	18	117	12	111	4e-29	117
rs:WP_009854557	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptococcus].	57.14	91	39	0	24	114	13	103	4e-29	113
rs:WP_003326783	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis group].	51.43	105	49	1	18	122	7	109	4e-29	115
rs:WP_027993817	phosphoribosyl-AMP cyclohydrolase [Sinorhizobium meliloti].	50.44	113	52	2	17	125	22	134	4e-29	114
tr:E0NWH9_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	50.00	102	50	1	11	112	2	102	4e-29	116
rs:WP_010290214	phosphoribosyl-ATP pyrophosphatase [Kurthia massiliensis].	47.79	113	58	1	17	128	2	114	4e-29	115
tr:X0TGH2_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_S03501 {ECO:0000313|EMBL:GAF92643.1}; Flags: Fragment;	50.98	102	49	1	24	124	11	112	4e-29	113
rs:WP_046798457	phosphoribosyl-AMP cyclohydrolase [Agrobacterium sp. LC34].	49.57	117	53	2	19	129	24	140	4e-29	114
rs:WP_005027895	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bilophila].	52.25	111	46	2	10	119	8	112	4e-29	114
rs:WP_039981499	phosphoribosyl-ATP pyrophosphatase [Selenomonas sp. oral taxon 149].	50.00	102	50	1	11	112	1	101	4e-29	116
rs:WP_014146599	phosphoribosyl-AMP cyclohydrolase [Methylomicrobium alcaliphilum].	43.86	114	63	1	18	130	9	122	4e-29	113
sp:HIS3_METLZ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	51.96	102	48	1	16	117	6	106	4e-29	113
rs:WP_013495016	phosphoribosyl-ATP pyrophosphatase [Thermaerobacter marianensis].	50.51	99	49	0	18	116	8	106	4e-29	116
rs:WP_039695480	phosphoribosyl-AMP cyclohydrolase [Streptococcus gallolyticus].	57.14	91	39	0	24	114	13	103	4e-29	113
rs:WP_026936640	phosphoribosyl-AMP cyclohydrolase [Gulosibacter molinativorax].	50.94	106	52	0	7	112	8	113	4e-29	114
rs:YP_004289844	phosphoribosyl-AMP cyclohydrolase [Methanobacterium lacus].	49.50	101	51	0	25	125	17	117	4e-29	114
rs:WP_027338401	phosphoribosyl-ATP diphosphatase [Helicobacter bilis].	48.00	100	52	0	18	117	6	105	4e-29	116
rs:WP_022384594	phosphoribosyl-ATP diphosphatase [Bacteroides sp. CAG:462].	54.46	101	40	2	11	111	3	97	4e-29	115
rs:WP_041187011	imidazole glycerol phosphate synthase [Candidatus Nitrospira defluvii].	47.27	110	57	1	11	119	1	110	4e-29	116
rs:WP_027956313	phosphoribosyl-ATP pyrophosphatase [Halobacillus kuroshimensis].	47.00	100	53	0	13	112	1	100	4e-29	115
rs:WP_042699149	phosphoribosyl-AMP cyclohydrolase [Methanocorpusculum bavaricum].	51.46	103	49	1	15	117	5	106	4e-29	113
rs:WP_029047637	phosphoribosyl-AMP cyclohydrolase [Cupriavidus sp. amp6].	47.66	107	55	1	16	121	7	113	4e-29	114
rs:WP_045750562	phosphoribosyl-AMP cyclohydrolase [Methylophilaceae bacterium MMS-10A-171].	53.61	97	44	1	24	119	12	108	4e-29	113
rs:WP_012934322	phosphoribosyl-ATP diphosphatase [Conexibacter woesei].	50.52	97	48	0	18	114	6	102	4e-29	115
rs:WP_009546397	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Cyanothece].	51.40	107	50	1	19	123	23	129	4e-29	114
rs:WP_007718315	phosphoribosyl-ATP pyrophosphatase [Brevibacillus sp. BC25].	51.00	100	49	0	13	112	7	106	4e-29	115
rs:WP_017841398	phosphoribosyl-AMP cyclohydrolase [Methylomicrobium buryatense].	43.86	114	63	1	18	130	9	122	4e-29	113
rs:WP_030540475	phosphoribosyl-AMP cyclohydrolase [Sphingobium sp. DC-2].	51.46	103	50	0	15	117	10	112	4e-29	113
rs:WP_029458616	phosphoribosyl-AMP cyclohydrolase [Dietzia alimentaria].	55.67	97	43	0	18	114	14	110	4e-29	113
sp:HIS3_MYCSJ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.61	97	45	0	16	112	9	105	4e-29	113
tr:X0X7R3_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_S28024 {ECO:0000313|EMBL:GAG32693.1};	48.72	117	56	2	17	131	22	136	4e-29	114
rs:WP_003779535	phosphoribosyl-AMP cyclohydrolase [Actinomyces naeslundii].	49.53	107	54	0	15	121	8	114	4e-29	113
rs:WP_003885732	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mycobacterium].	56.84	95	41	0	18	112	11	105	4e-29	113
rs:WP_009468446	phosphoribosyl-AMP cyclohydrolase [Roseibium sp. TrichSKD4].	44.70	132	57	3	8	123	10	141	4e-29	114
rs:WP_003330773	phosphoribosyl-AMP cyclohydrolase [Bacillus azotoformans].	51.58	95	46	0	18	112	6	100	5e-29	116
rs:WP_019314380	phosphoribosyl-AMP cyclohydrolase, partial [Streptococcus mutans].	51.06	94	46	0	21	114	10	103	5e-29	112
rs:WP_019672681	hypothetical protein [Psychrobacter lutiphocae].	53.61	97	44	1	18	113	39	135	5e-29	118
rs:WP_036157360	phosphoribosyl-ATP pyrophosphatase [Lysinibacillus odysseyi].	50.00	96	48	0	17	112	2	97	5e-29	115
rs:WP_042123284	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. FSL R5-0345].	52.08	96	46	0	18	113	18	113	5e-29	116
rs:WP_040450767	phosphoribosyl-AMP cyclohydrolase [Labrenzia alexandrii].	50.00	110	50	2	19	123	24	133	5e-29	114
rs:WP_036337675	phosphoribosyl-AMP cyclohydrolase [Mycobacterium aromaticivorans].	53.68	95	44	0	18	112	11	105	5e-29	113
rs:WP_005237439	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Enterococcus].	45.13	113	62	0	18	130	4	116	5e-29	115
rs:WP_043451569	phosphoribosyl-AMP cyclohydrolase, partial [Gordonia kroppenstedtii].	56.84	95	41	0	18	112	11	105	5e-29	112
rs:WP_011612061	phosphoribosyl-AMP cyclohydrolase [Trichodesmium erythraeum].	52.34	107	49	1	19	123	23	129	5e-29	114
tr:X1G7R7_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_L06013 {ECO:0000313|EMBL:GAH40890.1}; Flags: Fragment;	52.04	98	47	0	16	113	4	101	5e-29	113
rs:WP_012805086	phosphoribosyl-AMP cyclohydrolase [Brachybacterium faecium].	56.84	95	41	0	18	112	21	115	5e-29	113
rs:WP_015490437	hypothetical protein [Clavibacter michiganensis].	54.26	94	43	0	19	112	18	111	5e-29	113
rs:WP_016322288	phosphoribosyl-ATP diphosphatase [Oscillibacter sp. 1-3].	50.50	101	50	0	14	114	2	102	5e-29	115
rs:WP_028641519	phosphoribosyl-AMP cyclohydrolase [Novosphingobium acidiphilum].	48.18	110	55	2	19	126	3	112	5e-29	113
rs:WP_014778914	phosphoribosyl-AMP cyclohydrolase [Thiocystis violascens].	53.06	98	45	1	17	113	8	105	5e-29	113
rs:WP_018313911	phosphoribosyl-AMP cyclohydrolase [Cupriavidus sp. UYPR2.512].	47.66	107	55	1	16	121	7	113	5e-29	113
rs:WP_047106139	phosphoribosyl-AMP cyclohydrolase [Lactobacillus casei].	53.61	97	44	1	18	113	4	100	5e-29	112
rs:WP_025030412	phosphoribosyl-AMP cyclohydrolase [Nitratireductor aquibiodomus].	55.67	97	41	1	19	113	25	121	5e-29	114
rs:WP_028565238	phosphoribosyl-AMP cyclohydrolase [Salinispora tropica].	52.58	97	46	0	18	114	35	131	5e-29	114
rs:WP_040204147	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillus].	49.51	103	52	0	17	119	2	104	5e-29	115
rs:WP_009324623	phosphoribosyl-ATP pyrophosphatase [Subdoligranulum sp. 4_3_54A2FAA].	47.01	117	60	1	15	129	3	119	5e-29	115
tr:A0A0D8J1Q4_9FIRM	SubName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000313|EMBL:KJF40481.1};	47.01	117	60	1	15	129	3	119	5e-29	115
rs:WP_042184008	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. FSL H7-0737].	52.08	96	46	0	18	113	19	114	5e-29	116
rs:WP_027964824	phosphoribosyl-ATP pyrophosphatase [Halalkalibacillus halophilus].	44.26	122	66	1	11	130	1	122	5e-29	115
rs:WP_022167403	imidazole glycerol phosphate synthase subunit hisF [Clostridium sp. CAG:221].	50.00	92	46	0	22	113	12	103	5e-29	112
rs:WP_005101417	phosphoribosyl-ATP diphosphatase [Acinetobacter lwoffii].	53.61	97	44	1	18	113	10	106	5e-29	117
rs:WP_015768447	phosphoribosyl-AMP cyclohydrolase [Candidatus Accumulibacter phosphatis].	53.06	98	45	1	17	113	13	110	5e-29	113
tr:R5QR09_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	52.04	98	47	0	20	117	5	102	5e-29	115
rs:WP_039007462	phosphoribosyl-AMP cyclohydrolase [Cupriavidus sp. IDO].	46.73	107	56	1	16	121	7	113	5e-29	113
rs:WP_021770925	phosphoribosyl-ATP diphosphatase [Mitsuokella sp. oral taxon 131].	49.50	101	50	1	12	112	4	103	5e-29	116
rs:WP_004333178	phosphoribosyl-AMP cyclohydrolase [Thauera linaloolentis].	53.21	109	49	1	14	120	26	134	5e-29	114
sp:HIS3_CLAMS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	54.26	94	43	0	19	112	24	117	5e-29	113
rs:WP_032090192	imidazole glycerol phosphate synthase [bacterium LF-3].	52.04	98	47	0	20	117	5	102	5e-29	115
rs:WP_036144040	phosphoribosyl-ATP pyrophosphatase [Lysinibacillus sp. BF-4].	44.14	111	62	0	18	128	4	114	5e-29	115
rs:WP_012763118	phosphoribosyl-AMP cyclohydrolase [Ralstonia pickettii].	44.86	107	58	1	16	121	7	113	5e-29	114
tr:A0A063Z6Z8_9EURY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	54.08	98	44	1	24	121	8	104	5e-29	113
rs:WP_031390048	hypothetical protein [Clostridium sp. KNHs209].	53.47	101	47	0	13	113	228	328	5e-29	119
rs:WP_027146838	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. WSM3626].	48.72	117	48	2	19	123	25	141	5e-29	114
rs:WP_041972753	phosphoribosyl-AMP cyclohydrolase [Geobacter sp. OR-1].	51.55	97	46	1	24	119	11	107	5e-29	113
rs:WP_007008212	phosphoribosyl-AMP cyclohydrolase [Nitratireductor aquibiodomus].	55.67	97	41	1	19	113	25	121	5e-29	114
rs:WP_040400556	phosphoribosyl-AMP cyclohydrolase, partial [Amorphus coralli].	54.00	100	44	1	19	116	25	124	5e-29	113
rs:WP_037202238	phosphoribosyl-AMP cyclohydrolase [Rhizobium sp. OK494].	50.00	116	56	1	17	130	22	137	5e-29	114
rs:WP_018075196	phosphoribosyl-AMP cyclohydrolase [Novosphingobium nitrogenifigens].	50.00	108	52	2	19	124	17	124	5e-29	113
rs:WP_045931537	phosphoribosyl-AMP cyclohydrolase [Alcaligenes faecalis].	54.29	105	46	1	19	121	19	123	5e-29	114
rs:WP_040060229	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. REN51N].	52.69	93	44	0	20	112	8	100	5e-29	115
rs:WP_040464744	phosphoribosyl-AMP cyclohydrolase [Erythrobacter sp. NAP1].	50.53	95	47	0	19	113	10	104	5e-29	113
rs:WP_018004937	phosphoribosyl-AMP cyclohydrolase [Cupriavidus taiwanensis].	46.73	107	56	1	16	121	7	113	5e-29	113
rs:WP_040681919	phosphoribosyl-AMP cyclohydrolase [Methanobrevibacter boviskoreani].	46.85	111	59	0	21	131	10	120	6e-29	113
rs:WP_034640696	phosphoribosyl-AMP cyclohydrolase [Chitinilyticum aquatile].	46.49	114	60	1	18	130	9	122	6e-29	113
rs:WP_021620302	phosphoribosyl-ATP diphosphatase [Aneurinibacillus aneurinilyticus].	49.54	109	54	1	14	121	2	110	6e-29	115
rs:WP_000803966	phosphoribosyl-AMP cyclohydrolase [Bacillus thuringiensis].	55.56	90	40	0	24	113	8	97	6e-29	112
rs:WP_010332009	phosphoribosyl-ATP pyrophosphatase [Bacillus mojavensis].	53.68	95	44	0	18	112	7	101	6e-29	115
tr:B9QYY7_LABAD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	50.00	110	50	2	19	123	32	141	6e-29	114
rs:WP_007038918	phosphoribosyl-AMP cyclohydrolase [Thiorhodococcus drewsii].	53.61	97	44	1	18	113	11	107	6e-29	113
rs:WP_019153692	phosphoribosyl-ATP pyrophosphatase [Bacillus massiliosenegalensis].	50.98	102	48	1	11	112	1	100	6e-29	115
rs:WP_031554233	hypothetical protein, partial [Parvularcula oceani].	52.63	95	45	0	19	113	10	104	6e-29	112
rs:WP_015339964	phosphoribosyl-AMP cyclohydrolase [Rhizobium tropici].	49.59	123	57	2	10	130	18	137	6e-29	114
rs:WP_012109289	phosphoribosyl-ATP pyrophosphatase [Campylobacter hominis].	51.58	95	46	0	22	116	12	106	6e-29	116
rs:WP_025012361	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Lactobacillus].	53.61	97	44	1	18	113	4	100	6e-29	112
sp:HIS3_CLAM3	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.19	94	44	0	19	112	18	111	6e-29	113
rs:WP_018677437	phosphoribosyl-ATP diphosphatase [Acinetobacter tjernbergiae].	52.58	97	45	1	18	113	8	104	6e-29	116
sp:HIS3_METS3	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.63	95	45	0	19	113	8	102	6e-29	113
rs:WP_027680226	phosphoribosyl-AMP cyclohydrolase [Ralstonia sp. UNC404CL21Col].	44.86	107	58	1	16	121	7	113	6e-29	113
rs:WP_031649167	phosphoribosyl-AMP cyclohydrolase, partial [Listeria innocua].	51.02	98	47	1	16	113	2	98	6e-29	112
tr:A0A078MDL8_9BACI	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	48.04	102	53	0	18	119	4	105	6e-29	115
rs:WP_023549247	phosphoribosyl-AMP cyclohydrolase [Listeria monocytogenes].	49.47	95	48	0	24	118	9	103	6e-29	112
rs:WP_012589404	phosphoribosyl-AMP cyclohydrolase [Methylocella silvestris].	54.55	99	43	1	17	113	25	123	6e-29	113
rs:WP_002895139	phosphoribosyl-AMP cyclohydrolase [Streptococcus sanguinis].	51.46	103	48	1	21	121	10	112	6e-29	112
rs:WP_016646229	phosphoribosyl-ATP diphosphatase [Campylobacter ureolyticus].	51.58	95	46	0	23	117	12	106	6e-29	116
rs:WP_032950069	imidazole glycerol phosphate synthase [Lactococcus lactis].	52.58	97	46	0	20	116	5	101	6e-29	115
sp:HIS3_STRGC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	51.02	98	48	0	21	118	10	107	6e-29	112
rs:WP_027465725	phosphoribosyl-AMP cyclohydrolase [Curtobacterium sp. UNCCL17].	53.19	94	44	0	19	112	17	110	6e-29	113
rs:WP_002117475	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	55.56	90	40	0	24	113	8	97	6e-29	112
rs:WP_046522464	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. SA2-6].	52.58	97	46	0	16	112	2	98	6e-29	115
rs:WP_031804109	phosphoribosyl-AMP cyclohydrolase, partial [Pseudomonas aeruginosa].	57.61	92	38	1	18	108	8	99	6e-29	112
rs:WP_031408694	phosphoribosyl-AMP cyclohydrolase [Thiomonas sp. FB-Cd].	50.00	100	46	1	18	113	7	106	6e-29	113
rs:WP_015405223	phosphoribosyl-AMP cyclohydrolase [Desulfocapsa sulfexigens].	47.32	112	58	1	21	131	9	120	6e-29	113
rs:WP_016290797	phosphoribosyl-ATP diphosphatase [Lachnospiraceae bacterium 28-4].	52.48	101	48	0	13	113	228	328	7e-29	119
rs:WP_042400668	phosphoribosyl-AMP cyclohydrolase [Clostridium sp. JCC].	48.18	110	51	1	7	116	2	105	7e-29	112
rs:WP_020811306	phosphoribosyl-AMP cyclohydrolase [Agrobacterium tumefaciens].	51.28	117	51	3	19	129	24	140	7e-29	114
gp:CP002399_3832	Phosphoribosyl-AMP cyclohydrolase [Micromonospora sp. L5]	52.53	99	47	0	16	114	345	443	7e-29	119
rs:WP_041007251	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium plurifarium].	47.86	117	49	2	19	123	25	141	7e-29	114
rs:WP_045210673	phosphoribosyl-AMP cyclohydrolase [Desulfobulbus alkaliphilus].	56.52	92	39	1	24	114	10	101	7e-29	113
rs:WP_043586625	phosphoribosyl-AMP cyclohydrolase [Clavibacter michiganensis].	53.19	94	44	0	19	112	18	111	7e-29	113
rs:WP_042619698	phosphoribosyl-AMP cyclohydrolase [Agrobacterium tumefaciens].	52.25	111	49	2	19	125	24	134	7e-29	113
rs:WP_036241774	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. STM 4661].	54.00	100	44	1	19	116	25	124	7e-29	114
rs:WP_031471980	phosphoribosyl-AMP cyclohydrolase [[Clostridium] aminophilum].	50.52	97	48	0	18	114	4	100	7e-29	112
rs:WP_019262658	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Methanobrevibacter].	52.63	95	45	0	19	113	8	102	7e-29	113
rs:WP_034504938	phosphoribosyl-AMP cyclohydrolase [Agrobacterium rhizogenes].	50.00	116	56	1	17	130	22	137	7e-29	113
rs:WP_000803965	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacillus cereus group].	55.56	90	40	0	24	113	8	97	7e-29	112
rs:WP_000803964	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacillus].	55.56	90	40	0	24	113	8	97	7e-29	112
rs:WP_029115588	phosphoribosyl-AMP cyclohydrolase [Mycobacterium sp. URHB0044].	52.63	95	45	0	18	112	12	106	7e-29	112
rs:WP_005068556	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mycobacterium].	54.74	95	43	0	18	112	12	106	7e-29	112
rs:WP_012014387	phosphoribosyl-AMP cyclohydrolase [Salinispora tropica].	52.58	97	46	0	18	114	35	131	7e-29	113
rs:WP_027058739	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium loti].	48.72	117	48	2	19	123	25	141	7e-29	114
rs:WP_043054485	phosphoribosyl-ATP pyrophosphatase [Bacillus licheniformis].	53.68	95	44	0	18	112	7	101	7e-29	115
rs:WP_015915999	phosphoribosyl-AMP cyclohydrolase [Agrobacterium vitis].	48.67	113	54	2	17	125	21	133	7e-29	114
rs:WP_035766060	hypothetical protein [Butyrivibrio sp. NC2002].	50.50	101	50	0	13	113	222	322	7e-29	118
rs:WP_029473112	phosphoribosyl-AMP cyclohydrolase [Clostridiales bacterium VE202-08].	52.13	94	45	0	24	117	11	104	7e-29	112
rs:WP_018497996	phosphoribosyl-ATP pyrophosphatase [Leptotrichia wadei].	49.48	97	49	0	18	114	6	102	7e-29	115
rs:WP_009727533	phosphoribosyl-AMP cyclohydrolase [Methylophaga lonarensis].	51.43	105	49	1	19	121	30	134	7e-29	114
rs:WP_005057929	phosphoribosyl-AMP cyclohydrolase [Mycobacterium abscessus].	54.74	95	43	0	18	112	12	106	7e-29	112
rs:WP_042723767	phosphoribosyl-AMP cyclohydrolase, partial [Curtobacterium sp. B18].	52.13	94	45	0	19	112	17	110	7e-29	112
rs:WP_018166469	phosphoribosyl-AMP cyclohydrolase [Streptococcus minor].	53.19	94	44	0	21	114	10	103	7e-29	112
rs:WP_025268712	phosphoribosyl-AMP cyclohydrolase [Mycobacterium abscessus].	54.74	95	43	0	18	112	12	106	7e-29	112
rs:WP_005358489	imidazole glycerol phosphate synthase [Eubacterium ventriosum].	50.91	110	51	2	9	117	218	325	7e-29	118
rs:WP_036145667	phosphoribosyl-ATP pyrophosphatase [Lysinibacillus fusiformis].	47.12	104	55	0	18	121	5	108	7e-29	115
rs:WP_026508653	hypothetical protein [Butyrivibrio sp. MC2013].	50.00	106	53	0	13	118	241	346	8e-29	118
rs:WP_024977832	phosphoribosyl-AMP cyclohydrolase [Ralstonia pickettii].	44.86	107	58	1	16	121	7	113	8e-29	113
rs:WP_026974048	phosphoribosyl-ATP pyrophosphatase [Alicyclobacillus contaminans].	49.50	101	50	1	18	117	4	104	8e-29	116
tr:M5FLC7_9RHIZ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.00	100	44	1	19	116	46	145	8e-29	114
rs:WP_040770923	phosphoribosyl-AMP cyclohydrolase [Veillonella ratti].	51.06	94	46	0	24	117	10	103	8e-29	112
rs:WP_003586336	phosphoribosyl-AMP cyclohydrolase [Rhizobium leguminosarum].	48.39	124	59	2	10	131	19	139	8e-29	113
rs:WP_016838704	phosphoribosyl-ATP pyrophosphatase [Ureibacillus thermosphaericus].	50.96	104	50	1	17	119	6	109	8e-29	115
rs:WP_019348265	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mycobacterium].	55.79	95	42	0	18	112	11	105	8e-29	112
rs:WP_036120234	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Lysinibacillus].	47.12	104	55	0	18	121	5	108	8e-29	115
rs:WP_008291018	phosphoribosyl-AMP cyclohydrolase [Methylophaga thiooxydans].	50.00	108	52	2	18	123	7	114	8e-29	112
rs:WP_022763904	imidazole glycerol phosphate synthase [Butyrivibrio sp. XPD2006].	52.48	101	48	0	13	113	232	332	8e-29	118
rs:WP_010759915	phosphoribosyl-ATP diphosphatase [Enterococcus pallens].	53.68	95	44	0	18	112	3	97	8e-29	115
rs:WP_034514332	phosphoribosyl-AMP cyclohydrolase [Actinomyces sp. oral taxon 170].	50.00	112	55	1	10	120	7	118	8e-29	112
rs:WP_036687080	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Paenibacillus].	51.04	96	47	0	18	113	19	114	8e-29	115
rs:WP_045905986	phosphoribosyl-AMP cyclohydrolase [Clostridium botulinum].	54.44	90	41	0	23	112	16	105	8e-29	112
rs:WP_008199448	phosphoribosyl-AMP cyclohydrolase [Algoriphagus machipongonensis].	53.93	89	41	0	24	112	12	100	8e-29	115
rs:WP_025907439	phosphoribosyl-ATP pyrophosphatase [Bacillus flexus].	50.49	103	50	1	17	118	5	107	8e-29	115
rs:WP_023645792	phosphoribosyl-AMP cyclohydrolase [actinobacterium LLX17].	51.58	95	46	0	18	112	12	106	8e-29	112
rs:WP_037527276	phosphoribosyl-AMP cyclohydrolase, partial [Sphingomonas wittichii].	48.04	102	53	0	19	120	14	115	8e-29	112
rs:WP_042354273	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. MT2].	53.54	99	46	0	14	112	2	100	8e-29	115
rs:WP_010790040	phosphoribosyl-AMP cyclohydrolase [Bacillus atrophaeus].	51.43	105	49	1	18	122	7	109	8e-29	115
rs:WP_027510640	phosphoribosyl-AMP cyclohydrolase [Rhizobium sullae].	51.46	103	49	1	19	120	29	131	8e-29	114
rs:WP_016358378	phosphoribosyl-AMP cyclohydrolase [Methanobrevibacter sp. AbM4].	46.85	111	59	0	21	131	10	120	8e-29	113
tr:A0A0C2XY66_BACBA	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	43.33	120	67	1	11	129	1	120	8e-29	115
rs:WP_045203050	phosphoribosyl-AMP cyclohydrolase [Burkholderiaceae bacterium 26].	44.86	107	58	1	16	121	7	113	8e-29	113
rs:WP_036726248	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. FSL R7-277].	51.02	98	48	0	16	113	17	114	8e-29	115
rs:WP_045661009	phosphoribosyl-ATP pyrophosphatase [Clostridiaceae bacterium BRH_c20a].	51.58	95	46	0	18	112	9	103	8e-29	114
rs:WP_006306355	phosphoribosyl-ATP pyrophosphatase [Centipeda periodontii].	49.02	102	51	1	11	112	1	101	8e-29	115
rs:WP_013459092	phosphoribosyl-ATP pyrophosphatase [Sulfuricurvum kujiense].	52.63	95	45	0	25	119	13	107	8e-29	115
rs:WP_036087012	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Listeria].	54.55	99	44	1	17	115	2	99	9e-29	112
rs:WP_013329745	phosphoribosyl-AMP cyclohydrolase [Methanolacinia petrolearia].	49.50	101	50	1	18	117	4	104	9e-29	112
rs:WP_026588885	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. NSP9.1].	52.04	98	47	0	18	115	7	104	9e-29	115
rs:WP_012448420	phosphoribosyl-ATP pyrophosphatase [Natranaerobius thermophilus].	50.00	100	50	0	17	116	2	101	9e-29	115
rs:WP_019383313	phosphoribosyl-ATP pyrophosphatase [Bacillus oceanisediminis].	48.48	99	51	0	14	112	2	100	9e-29	115
rs:WP_022372997	phosphoribosyl-AMP cyclohydrolase [Sutterella sp. CAG:397].	46.43	112	59	1	18	128	6	117	9e-29	112
rs:WP_035322155	imidazole glycerol phosphate synthase [Clostridium sp. KLE 1755].	52.94	102	42	1	25	126	1	96	9e-29	114
rs:WP_029566930	phosphoribosyl-ATP pyrophosphatase [Bacillus cibi].	50.51	99	49	0	14	112	2	100	9e-29	115
rs:WP_040037415	phosphoribosyl-ATP pyrophosphatase [Bacillaceae bacterium MTCC 10057].	43.33	120	67	1	11	129	1	120	9e-29	115
rs:WP_023964531	phosphoribosyl-AMP cyclohydrolase [Paenibacillus sp. JCM 10914].	45.79	107	58	0	10	116	10	116	9e-29	115
tr:A3WCC9_9SPHN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	50.53	95	47	0	19	113	32	126	9e-29	113
rs:WP_007708324	phosphoribosyl-AMP cyclohydrolase [Sphingobium sp. AP49].	50.51	99	49	0	15	113	10	108	9e-29	112
rs:WP_044995703	phosphoribosyl-AMP cyclohydrolase [Lachnospiraceae bacterium JC7].	48.51	101	52	0	12	112	5	105	9e-29	112
tr:X0T1K6_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_C00749 {ECO:0000313|EMBL:GAF82037.1};	53.06	98	46	0	16	113	3	100	9e-29	112
rs:WP_015893492	phosphoribosyl-ATP pyrophosphatase [Brevibacillus brevis].	50.00	100	50	0	13	112	7	106	9e-29	115
rs:WP_009331839	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. 2_A_57_CT2].	48.48	99	51	0	14	112	2	100	9e-29	115
rs:WP_047153495	phosphoribosyl-ATP pyrophosphatase [Aneurinibacillus tyrosinisolvens].	51.52	99	48	0	14	112	2	100	1e-28	115
sp:HIS3_LISMC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	49.47	95	48	0	24	118	9	103	1e-28	112
rs:WP_033612036	phosphoribosyl-AMP cyclohydrolase [Lactobacillus paraplantarum].	52.13	94	45	0	24	117	10	103	1e-28	112
rs:WP_024019960	phosphoribosyl-AMP cyclohydrolase [Sphingobium sp. C100].	48.18	110	56	1	15	123	10	119	1e-28	112
tr:W7PZL5_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	58.62	87	36	0	44	130	1	87	1e-28	112
rs:WP_018097836	phosphoribosyl-AMP cyclohydrolase [Sinorhizobium meliloti].	49.56	113	53	2	17	125	22	134	1e-28	113
rs:WP_021725625	phosphoribosyl-AMP cyclohydrolase [Olsenella profusa].	51.49	101	49	0	13	113	6	106	1e-28	112
rs:WP_019774026	phosphoribosyl-AMP cyclohydrolase [Streptococcus sobrinus].	50.48	105	46	1	10	114	5	103	1e-28	112
tr:W7YZF0_9BACI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	52.48	101	47	1	20	119	6	106	1e-28	114
rs:WP_044360191	phosphoribosyl-ATP pyrophosphatase [Staphylococcus microti].	52.69	93	44	0	24	116	10	102	1e-28	115
rs:WP_040969654	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. ORS3324].	49.57	117	47	2	19	123	25	141	1e-28	113
rs:WP_007596497	phosphoribosyl-AMP cyclohydrolase [Rhizobium sp. PDO1-076].	50.44	113	52	2	17	125	23	135	1e-28	113
sp:HIS3_CUPTR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	46.73	107	56	1	16	121	7	113	1e-28	112
sp:HIS3_LISMO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	49.47	95	48	0	24	118	9	103	1e-28	112
rs:WP_043778100	imidazole glycerol phosphate synthase, partial [Deinococcus ficus].	49.53	107	54	0	13	119	1	107	1e-28	114
rs:WP_006362996	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Slackia].	48.25	114	57	1	18	129	6	119	1e-28	115
rs:WP_024962072	phosphoribosyl-ATP diphosphatase [Campylobacter ureolyticus].	52.63	95	45	0	23	117	12	106	1e-28	115
rs:WP_016082328	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacillus].	55.56	90	40	0	24	113	8	97	1e-28	112
rs:WP_034159483	phosphoribosyl-AMP cyclohydrolase [Sphingomonas sp. ERG5].	50.00	102	51	0	19	120	14	115	1e-28	112
rs:WP_036715354	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. P1XP2].	44.64	112	62	0	2	113	1	112	1e-28	115
rs:WP_024040587	phosphoribosyl-AMP cyclohydrolase [Clostridium butyricum].	54.44	90	41	0	24	113	17	106	1e-28	112
rs:WP_015426395	phosphoribosyl-AMP cyclohydrolase [Lactococcus lactis].	54.26	94	43	0	20	113	5	98	1e-28	115
tr:U1CSB5_ENTGA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ERE49488.1}; Flags: Fragment;	54.26	94	43	0	20	113	5	98	1e-28	112
rs:WP_035441460	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. JCM 19046].	52.48	101	47	1	20	119	6	106	1e-28	114
rs:WP_022536808	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Burkholderiaceae].	46.73	107	56	1	16	121	7	113	1e-28	112
rs:WP_019394929	phosphoribosyl-ATP pyrophosphatase [Bacillus endophyticus].	52.69	93	44	0	20	112	8	100	1e-28	114
rs:WP_002917048	phosphoribosyl-AMP cyclohydrolase [Streptococcus sanguinis].	52.04	98	47	0	21	118	10	107	1e-28	112
rs:WP_022149216	histidine biosynthesis protein HisIE [Prevotella sp. CAG:1320].	55.56	90	40	0	23	112	9	98	1e-28	115
rs:WP_043747750	phosphoribosyl-AMP cyclohydrolase [Thiorhodococcus sp. AK35].	53.06	98	45	1	17	113	8	105	1e-28	112
sp:HIS3_METST	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	47.12	104	55	0	21	124	11	114	1e-28	112
rs:WP_027008287	phosphoribosyl-ATP diphosphatase [Conexibacter woesei].	49.50	101	51	0	13	113	1	101	1e-28	114
rs:WP_018199413	hypothetical protein [Hydrogenedentes bacterium JGI 0000077-D07].	51.38	109	52	1	18	126	7	114	1e-28	112
rs:WP_026804900	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Arcobacter].	51.65	91	44	0	24	114	14	104	1e-28	115
rs:WP_044662087	phosphoribosyl-AMP cyclohydrolase [Sphingobium sp. YBL2].	49.09	110	54	1	15	124	10	117	1e-28	112
rs:WP_047093717	phosphoribosyl-AMP cyclohydrolase [Erythrobacter marinus].	49.06	106	53	1	19	123	3	108	1e-28	112
rs:WP_047029978	phosphoribosyl-AMP cyclohydrolase [Hoeflea sp. IMCC20628].	50.46	109	50	2	19	123	24	132	1e-28	113
rs:WP_007614016	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillus].	47.22	108	57	0	18	125	7	114	1e-28	114
rs:WP_029107671	phosphoribosyl-AMP cyclohydrolase [Mycobacterium sp. URHD0025].	55.79	95	42	0	18	112	12	106	1e-28	112
tr:E8R0V5_ISOPI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216}; Flags: Precursor;	50.86	116	54	3	19	131	25	140	1e-28	114
rs:WP_023929380	phosphoribosyl-ATP diphosphatase [Helicobacter canis].	50.00	98	49	0	16	113	13	110	1e-28	115
sp:HIS3_MYCSK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.58	97	46	0	16	112	9	105	1e-28	112
rs:WP_041549442	phosphoribosyl-AMP cyclohydrolase [Olsenella uli].	52.08	96	46	0	18	113	1	96	1e-28	111
rs:WP_010771272	phosphoribosyl-AMP cyclohydrolase [Enterococcus caccae].	51.61	93	45	0	24	116	8	100	1e-28	111
rs:WP_019914372	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. HW567].	52.08	96	46	0	18	113	19	114	1e-28	115
rs:WP_034564396	phosphoribosyl-ATP diphosphatase [Helicobacter bilis].	48.00	100	52	0	18	117	6	105	1e-28	115
rs:WP_006694224	phosphoribosyl-ATP pyrophosphatase [Selenomonas noxia].	49.02	102	51	1	11	112	1	101	1e-28	115
rs:WP_046351644	phosphoribosyl-AMP cyclohydrolase [Janthinobacterium sp. B9-8].	46.49	114	60	1	18	130	7	120	1e-28	112
rs:WP_003905605	phosphoribosyl-AMP cyclohydrolase [Mycobacterium tuberculosis].	53.68	95	44	0	18	112	11	105	1e-28	112
rs:WP_016922008	phosphoribosyl-AMP cyclohydrolase [Methylocystis parvus].	47.97	123	55	3	7	125	9	126	1e-28	112
rs:WP_036126729	phosphoribosyl-ATP pyrophosphatase [Lysinibacillus sphaericus].	42.86	112	64	0	17	128	4	115	1e-28	114
rs:WP_038584631	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. FSL H7-0357].	52.08	96	46	0	18	113	19	114	1e-28	115
rs:WP_044431570	phosphoribosyl-AMP cyclohydrolase [Lactobacillus plantarum].	53.19	94	44	0	24	117	10	103	1e-28	112
rs:WP_031292074	phosphoribosyl-AMP cyclohydrolase [Sphingobium baderi].	48.18	110	55	1	15	124	10	117	1e-28	112
rs:WP_022254584	phosphoribosyl-AMP cyclohydrolase [Firmicutes bacterium CAG:466].	48.00	100	52	0	13	112	2	101	1e-28	114
rs:WP_013295514	phosphoribosyl-AMP cyclohydrolase [Methanothermobacter marburgensis].	50.00	100	50	0	29	128	1	100	1e-28	112
rs:WP_010937017	phosphoribosyl-AMP cyclohydrolase [Dehalococcoides mccartyi].	52.00	100	48	0	18	117	3	102	1e-28	111
rs:WP_003185594	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillus].	53.68	95	44	0	18	112	7	101	1e-28	114
rs:WP_024722073	imidazole glycerol phosphate synthase [Clostridiales bacterium VE202-01].	52.63	95	45	0	20	114	5	99	1e-28	114
tr:A0A0A1H9D8_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	50.00	104	51	1	17	119	17	120	1e-28	114
sp:HIS3_RALPJ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	43.93	107	59	1	16	121	7	113	1e-28	112
rs:WP_018208637	phosphoribosyl-AMP cyclohydrolase [Sinorhizobium medicae].	53.92	102	45	1	17	116	23	124	1e-28	113
rs:WP_006691948	phosphoribosyl-ATP pyrophosphatase [Selenomonas infelix].	50.98	102	49	1	11	112	1	101	1e-28	115
rs:WP_024925322	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mesorhizobium].	51.96	102	47	1	17	116	23	124	1e-28	113
rs:WP_026528858	imidazole glycerol phosphate synthase [Butyrivibrio sp. VCD2006].	47.57	103	54	0	12	114	4	106	1e-28	114
rs:WP_010474077	phosphoribosyl-AMP cyclohydrolase [Acaryochloris sp. CCMEE 5410].	52.34	107	49	1	19	123	23	129	1e-28	113
rs:WP_025549828	phosphoribosyl-AMP cyclohydrolase [Sphingobium sp. KK22].	49.09	110	54	1	15	124	10	117	1e-28	112
rs:WP_003415208	phosphoribosyl-AMP cyclohydrolase [Clostridium butyricum].	54.44	90	41	0	24	113	17	106	1e-28	112
rs:WP_026567785	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. UNC41MFS5].	52.08	96	46	0	17	112	2	97	1e-28	114
rs:WP_015025967	phosphoribosyl-AMP cyclohydrolase [Psychroflexus torquis].	48.45	97	50	0	15	111	2	98	1e-28	114
rs:WP_029869255	phosphoribosyl-AMP cyclohydrolase [Rhizobium sp. JGI 0001005-L20].	50.44	113	52	2	17	125	23	135	1e-28	113
rs:WP_002580919	phosphoribosyl-AMP cyclohydrolase [Clostridium butyricum].	54.44	90	41	0	24	113	17	106	1e-28	112
rs:WP_014600569	phosphoribosyl-AMP cyclohydrolase [Listeria monocytogenes].	49.47	95	48	0	24	118	9	103	1e-28	111
rs:WP_035223016	phosphoribosyl-AMP cyclohydrolase [Agrobacterium tumefaciens].	50.43	117	52	2	19	129	24	140	1e-28	113
tr:A0A0A1F4Y1_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	52.13	94	44	1	25	117	1	94	1e-28	112
rs:WP_002912755	phosphoribosyl-AMP cyclohydrolase [Streptococcus sanguinis].	52.04	98	47	0	21	118	10	107	1e-28	112
rs:WP_003087682	phosphoribosyl-AMP cyclohydrolase [Streptococcus ratti].	52.69	93	44	0	22	114	11	103	1e-28	112
rs:WP_028400388	phosphoribosyl-AMP cyclohydrolase [Bacillus panaciterrae].	52.69	93	44	0	24	116	10	102	1e-28	111
rs:WP_045472790	phosphoribosyl-AMP cyclohydrolase, partial [Burkholderiales bacterium GJ-E10].	50.00	104	51	1	17	119	17	120	1e-28	112
rs:WP_037447943	phosphoribosyl-AMP cyclohydrolase [Sphingobium chlorophenolicum].	49.09	110	54	1	15	124	10	117	1e-28	112
rs:WP_046753418	phosphoribosyl-AMP cyclohydrolase [Mycobacterium elephantis].	54.74	95	43	0	18	112	11	105	1e-28	112
rs:WP_014705535	phosphoribosyl-AMP cyclohydrolase [Methylophaga nitratireducenticrescens].	44.74	114	62	1	18	130	8	121	1e-28	112
rs:WP_036818878	phosphoribosyl-ATP pyrophosphatase [Pontibacillus yanchengensis].	50.52	97	48	0	18	114	6	102	1e-28	114
rs:WP_041624155	phosphoribosyl-AMP cyclohydrolase, partial [Spirochaeta thermophila].	55.43	92	40	1	23	113	2	93	1e-28	111
rs:WP_043572626	phosphoribosyl-AMP cyclohydrolase [Actinopolyspora erythraea].	53.61	97	45	0	16	112	3	99	1e-28	112
rs:WP_017379177	hypothetical protein [Paenisporosarcina sp. TG-14].	46.15	104	56	0	13	116	4	107	1e-28	114
rs:WP_039128433	phosphoribosyl-AMP cyclohydrolase [Leisingera sp. ANG-Vp].	53.33	105	47	1	19	121	26	130	1e-28	113
tr:X1M3A8_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_L04718 {ECO:0000313|EMBL:GAI12531.1};	51.58	95	46	0	18	112	2	96	1e-28	112
rs:WP_027445834	phosphoribosyl-ATP pyrophosphatase [Pontibacillus marinus].	51.52	99	48	0	18	116	6	104	1e-28	114
rs:WP_035271237	phosphoribosyl-AMP cyclohydrolase [Desulfonatronum thiodismutans].	55.10	98	43	1	24	120	10	107	1e-28	112
sp:HIS3_SINMW	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.92	102	45	1	17	116	23	124	1e-28	113
rs:WP_012818402	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. Y412MC10].	49.49	99	50	0	18	116	18	116	1e-28	115
rs:WP_045229084	phosphoribosyl-AMP cyclohydrolase [Agrobacterium rubi].	51.24	121	53	3	15	129	20	140	1e-28	113
rs:WP_021142680	phosphoribosyl-AMP cyclohydrolase [Streptococcus equinus].	54.26	94	43	0	21	114	10	103	1e-28	111
rs:WP_027029247	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium loti].	48.72	117	48	2	19	123	25	141	1e-28	113
rs:WP_033043249	phosphoribosyl-AMP cyclohydrolase [Sinorhizobium medicae].	53.92	102	45	1	17	116	23	124	1e-28	112
rs:WP_027976354	phosphoribosyl-AMP cyclohydrolase [Streptococcus devriesei].	54.84	93	42	0	24	116	13	105	1e-28	112
rs:WP_013048078	phosphoribosyl-ATP pyrophosphatase [Aminobacterium colombiense].	45.61	114	61	1	13	125	2	115	1e-28	114
rs:WP_045503632	phosphoribosyl-AMP cyclohydrolase [Streptococcus gordonii].	50.00	104	52	0	21	124	10	113	1e-28	112
rs:WP_047206192	imidazole glycerol phosphate synthase [Lactococcus lactis].	54.26	94	43	0	20	113	5	98	1e-28	114
rs:WP_034452566	imidazole glycerol phosphate synthase [Butyrivibrio sp. AE2032].	53.33	90	42	0	25	114	1	90	1e-28	114
rs:WP_034480849	phosphoribosyl-AMP cyclohydrolase [Agrobacterium rhizogenes].	50.00	116	56	1	17	130	22	137	1e-28	112
rs:WP_029061680	phosphoribosyl-AMP cyclohydrolase [Labrenzia sp. DG1229].	52.00	100	46	1	19	116	24	123	1e-28	113
rs:WP_046319741	phosphoribosyl-AMP cyclohydrolase [Mycobacterium sp. UM_Kg1].	55.79	95	42	0	18	112	13	107	1e-28	112
rs:WP_026602365	phosphoribosyl-AMP cyclohydrolase [Methylomonas sp. 11b].	43.86	114	63	1	18	130	9	122	1e-28	112
rs:WP_043417041	phosphoribosyl-AMP cyclohydrolase, partial [Streptomyces pluripotens].	43.93	107	59	1	16	121	7	113	1e-28	112
rs:WP_038600967	imidazole glycerol phosphate synthase [Lactococcus lactis].	53.68	95	44	0	20	114	5	99	1e-28	114
sp:HIS3_RALME	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	46.73	107	56	1	16	121	7	113	1e-28	112
rs:WP_000803962	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacillus].	54.44	90	41	0	24	113	8	97	1e-28	111
sp:HIS3_LISMH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	49.47	95	48	0	24	118	9	103	2e-28	111
rs:WP_041095723	phosphoribosyl-ATP pyrophosphatase [Bacillus badius].	45.13	113	61	1	18	129	6	118	2e-28	114
tr:K9EKI9_9CYAN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	55.34	103	44	1	19	119	82	184	2e-28	114
rs:WP_036355924	phosphoribosyl-AMP cyclohydrolase [Mycobacterium asiaticum].	52.83	106	48	1	18	121	11	116	2e-28	112
tr:E1QW95_OLSUV	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	49.50	101	51	0	13	113	26	126	2e-28	112
rs:WP_036444282	phosphoribosyl-AMP cyclohydrolase [Mycobacterium vulneris].	52.88	104	48	1	10	112	2	105	2e-28	111
rs:WP_026623367	phosphoribosyl-AMP cyclohydrolase [Ensifer sp. WSM1721].	50.44	113	52	2	17	125	22	134	2e-28	112
rs:WP_027968556	phosphoribosyl-AMP cyclohydrolase [Streptococcus equinus].	54.26	94	43	0	21	114	10	103	2e-28	111
rs:WP_044626157	phosphoribosyl-ATP pyrophosphatase [Tamlana nanhaiensis].	49.47	95	48	0	17	111	2	96	2e-28	114
rs:WP_000803958	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	55.56	90	40	0	24	113	8	97	2e-28	111
rs:WP_014418970	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillus].	47.22	108	57	0	18	125	7	114	2e-28	114
rs:WP_025707065	phosphoribosyl-ATP pyrophosphatase [Paenibacillus graminis].	52.08	96	46	0	18	113	19	114	2e-28	115
rs:WP_026889345	phosphoribosyl-AMP cyclohydrolase [Clostridium beijerinckii].	53.33	90	42	0	24	113	17	106	2e-28	111
sp:HIS3_GEODF	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	51.02	98	47	1	23	119	10	107	2e-28	112
tr:A0A097CS90_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	55.06	89	40	0	26	114	1	89	2e-28	111
rs:WP_043154743	phosphoribosyl-AMP cyclohydrolase [Sphingobium sp. Ant17].	50.98	102	50	0	15	116	10	111	2e-28	112
rs:WP_023555372	phosphoribosyl-ATP pyrophosphatase [Brevibacillus panacihumi].	53.68	95	44	0	18	112	10	104	2e-28	114
rs:WP_029343941	imidazole glycerol phosphate synthase [Lactococcus lactis].	54.26	94	43	0	20	113	5	98	2e-28	114
sp:HIS3_METMJ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.19	94	44	0	24	117	8	101	2e-28	112
rs:WP_015941401	phosphoribosyl-ATP pyrophosphatase [Chloroflexus aggregans].	54.84	93	42	0	21	113	5	97	2e-28	114
rs:WP_035772126	phosphoribosyl-AMP cyclohydrolase, partial [Arthrobacter sp. Br18].	53.06	98	46	0	15	112	25	122	2e-28	112
rs:WP_041439934	phosphoribosyl-AMP cyclohydrolase [Thermovibrio ammonificans].	47.27	110	52	1	9	118	2	105	2e-28	111
sp:HIS2_LACLA	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	54.26	94	43	0	20	113	5	98	2e-28	114
rs:WP_021317862	phosphoribosyl-AMP cyclohydrolase [Sphingobium ummariense].	50.98	102	50	0	15	116	10	111	2e-28	112
rs:WP_038188871	phosphoribosyl-ATP pyrophosphatase [Viridibacillus arenosi].	47.17	106	56	0	18	123	5	110	2e-28	114
rs:WP_003495568	phosphoribosyl-AMP cyclohydrolase [Agrobacterium tumefaciens].	50.43	117	52	2	19	129	24	140	2e-28	112
rs:WP_037100730	phosphoribosyl-AMP cyclohydrolase [Rhizobium sp. OK665].	50.44	113	52	2	17	125	22	134	2e-28	112
rs:WP_027331497	phosphoribosyl-AMP cyclohydrolase [Mycobacterium tusciae].	54.64	97	44	0	16	112	9	105	2e-28	111
tr:I4C478_DESTA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	51.38	109	50	3	8	113	2	110	2e-28	112
rs:WP_006728437	phosphoribosyl-AMP cyclohydrolase [Agrobacterium albertimagni].	46.55	116	60	1	17	130	23	138	2e-28	112
rs:WP_007144242	phosphoribosyl-AMP cyclohydrolase [Methylophaga aminisulfidivorans].	44.74	114	62	1	18	130	8	121	2e-28	112
rs:WP_028454978	phosphoribosyl-AMP cyclohydrolase [Chitinilyticum litopenaei].	44.44	126	68	2	6	130	4	128	2e-28	112
rs:WP_009241944	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacteria].	43.93	107	59	1	16	121	7	113	2e-28	112
rs:WP_012897812	histidine biosynthesis bifunctional protein HisIE [Lactococcus lactis].	54.26	94	43	0	20	113	5	98	2e-28	114
rs:WP_027024993	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. URHA0056].	47.86	117	49	2	19	123	25	141	2e-28	112
rs:WP_006678151	phosphoribosyl-ATP pyrophosphatase [Paenibacillus dendritiformis].	52.63	95	45	0	18	112	21	115	2e-28	115
rs:WP_031559652	imidazole glycerol phosphate synthase [Lactococcus lactis].	54.26	94	43	0	20	113	5	98	2e-28	114
sp:HIS3_BACC2	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	55.56	90	40	0	24	113	8	97	2e-28	111
rs:WP_042685823	phosphoribosyl-AMP cyclohydrolase [Methermicoccus shengliensis].	48.96	96	49	0	18	113	3	98	2e-28	111
rs:WP_013958200	phosphoribosyl-AMP cyclohydrolase [Cupriavidus necator].	46.73	107	56	1	16	121	7	113	2e-28	112
rs:WP_039463242	phosphoribosyl-ATP pyrophosphatase [Photobacterium gaetbulicola].	52.81	89	42	0	24	112	14	102	2e-28	114
tr:A0A081RIB9_SPHCR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216}; Flags: Precursor;	49.09	110	54	1	15	124	20	127	2e-28	112
gp:LLU92974_11	HisIE [Lactococcus lactis subsp. lactis NCDO 2118]	54.26	94	43	0	20	113	5	98	2e-28	114
rs:WP_021721688	phosphoribosyl-AMP cyclohydrolase [Lactococcus lactis].	54.26	94	43	0	20	113	5	98	2e-28	114
rs:WP_009659375	phosphoribosyl-AMP cyclohydrolase [Streptococcus sp. AS14].	52.04	98	47	0	21	118	10	107	2e-28	111
rs:WP_013490105	phosphoribosyl-ATP pyrophosphatase [Bacillus cellulosilyticus].	43.97	116	65	0	15	130	2	117	2e-28	114
rs:WP_042202882	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. G4].	52.08	96	46	0	18	113	12	107	2e-28	114
rs:WP_014588369	phosphoribosyl-AMP cyclohydrolase [Mycobacterium tuberculosis].	52.63	95	45	0	18	112	11	105	2e-28	111
rs:WP_037153769	phosphoribosyl-AMP cyclohydrolase [Rhizobium freirei].	50.00	120	53	3	10	125	18	134	2e-28	112
rs:WP_020648455	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Solimonas].	51.96	102	48	1	19	119	25	126	2e-28	112
rs:WP_027204885	imidazole glycerol phosphate synthase [Butyrivibrio fibrisolvens].	55.56	90	40	0	25	114	1	90	2e-28	114
rs:WP_010812325	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Burkholderiaceae].	46.73	107	56	1	16	121	7	113	2e-28	112
sp:HIS3_CUPNH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	46.73	107	56	1	16	121	7	113	2e-28	112
tr:E8T2B7_THEA1	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	48.15	108	50	1	9	116	9	110	2e-28	111
rs:WP_030135559	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mycobacterium].	53.61	97	45	0	16	112	9	105	2e-28	111
rs:WP_035785249	MULTISPECIES: hypothetical protein [Butyrivibrio].	53.12	96	45	0	18	113	227	322	2e-28	117
rs:WP_000803961	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacillus cereus group].	54.44	90	41	0	24	113	8	97	2e-28	111
rs:WP_020917079	phosphoribosyl-AMP cyclohydrolase [Streptococcus lutetiensis].	56.04	91	40	0	24	114	13	103	2e-28	111
rs:WP_017418841	phosphoribosyl-ATP pyrophosphatase [Bacillus amyloliquefaciens].	47.22	108	57	0	18	125	7	114	2e-28	114
rs:WP_013466708	phosphoribosyl-ATP pyrophosphatase [Thermococcus barophilus].	55.56	90	39	1	24	113	15	103	2e-28	114
sp:HIS3_CLOB8	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.33	90	42	0	24	113	17	106	2e-28	111
rs:WP_010175256	phosphoribosyl-ATP pyrophosphatase [Bacillus coahuilensis].	51.61	93	45	0	20	112	7	99	2e-28	114
rs:WP_020484501	phosphoribosyl-AMP cyclohydrolase [Methylomonas sp. MK1].	44.64	112	61	1	18	128	9	120	2e-28	112
rs:WP_046178203	phosphoribosyl-ATP pyrophosphatase [Domibacillus sp. PAMC 80007].	50.53	95	47	0	18	112	5	99	2e-28	114
rs:WP_018713548	hypothetical protein [Campylobacter ureolyticus].	52.63	95	45	0	23	117	12	106	2e-28	115
tr:A0A068JNU6_9DELT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	55.10	98	43	1	24	120	16	113	2e-28	112
rs:WP_039943318	phosphoribosyl-AMP cyclohydrolase [Alcaligenes faecalis].	52.88	104	47	1	19	120	22	125	2e-28	112
rs:WP_017211520	phosphoribosyl-AMP cyclohydrolase [Clostridium beijerinckii].	53.33	90	42	0	24	113	17	106	2e-28	111
rs:WP_023189269	phosphoribosyl-AMP cyclohydrolase [Lactococcus lactis].	54.26	94	43	0	20	113	5	98	2e-28	114
rs:WP_035355377	imidazole glycerol phosphate synthase [Bacillus ginsengihumi].	51.00	100	48	1	24	122	8	107	2e-28	114
rs:WP_023763580	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. LNHC232B00].	47.01	117	50	2	19	123	25	141	2e-28	112
rs:WP_017481957	phosphoribosyl-ATP diphosphatase [Acinetobacter calcoaceticus].	52.58	97	45	1	18	113	8	104	2e-28	115
rs:WP_023613923	MULTISPECIES: hypothetical protein [Bacillus].	53.68	95	44	0	18	112	6	100	2e-28	114
rs:WP_026582045	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. J33].	48.00	100	52	0	13	112	1	100	2e-28	114
rs:WP_016961136	phosphoribosyl-AMP cyclohydrolase [Enterovibrio norvegicus].	47.17	106	53	1	24	129	21	123	2e-28	114
rs:WP_024363893	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Lysinibacillus].	46.67	105	56	0	17	121	4	108	2e-28	114
rs:WP_039696592	phosphoribosyl-AMP cyclohydrolase [Streptococcus equinus].	56.04	91	40	0	24	114	13	103	2e-28	111
rs:WP_006639206	phosphoribosyl-AMP cyclohydrolase [Bacillus sonorensis].	52.04	98	47	0	18	115	7	104	2e-28	114
rs:WP_023974254	phosphoribosyl-AMP cyclohydrolase [Clostridium pasteurianum].	53.33	90	42	0	24	113	17	106	2e-28	111
rs:WP_042506800	phosphoribosyl-ATP pyrophosphatase [Algibacter lectus].	44.64	112	52	1	17	118	2	113	2e-28	114
rs:WP_018065643	hypothetical protein [Martelella mediterranea].	53.54	99	44	1	17	113	21	119	2e-28	112
rs:WP_046838408	imidazole glycerol phosphate synthase [Candidatus Synechococcus spongiarum].	60.67	89	34	1	26	113	1	89	2e-28	114
rs:WP_041704501	imidazole glycerol phosphate synthase [Lachnoclostridium phytofermentans].	54.55	88	40	0	26	113	1	88	2e-28	113
tr:G0GA93_SPITZ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.55	99	43	2	23	119	21	119	2e-28	112
rs:WP_007684175	phosphoribosyl-AMP cyclohydrolase [Novosphingobium sp. AP12].	50.00	106	52	1	19	123	18	123	2e-28	111
rs:WP_046640236	phosphoribosyl-AMP cyclohydrolase [Neorhizobium galegae].	47.01	117	60	1	17	131	22	138	2e-28	112
rs:WP_046165382	phosphoribosyl-AMP cyclohydrolase [Streptococcus gordonii].	51.02	98	48	0	21	118	10	107	2e-28	111
rs:WP_002933349	phosphoribosyl-AMP cyclohydrolase [Streptococcus sanguinis].	51.02	98	48	0	21	118	10	107	2e-28	111
rs:WP_031674452	phosphoribosyl-AMP cyclohydrolase [Listeria monocytogenes].	48.42	95	49	0	24	118	9	103	2e-28	111
rs:WP_037463014	phosphoribosyl-AMP cyclohydrolase [Sphingobium herbicidovorans].	47.83	115	57	2	15	128	10	122	2e-28	111
rs:WP_023783213	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. LNHC220B00].	47.86	117	49	2	19	123	25	141	2e-28	112
rs:WP_025729400	imidazole glycerol phosphate synthase [Bacillus ginsengihumi].	51.00	100	48	1	24	122	8	107	2e-28	114
rs:WP_043731798	phosphoribosyl-AMP cyclohydrolase, partial [Kutzneria sp. 744].	56.84	95	41	0	18	112	13	107	2e-28	111
rs:WP_022709988	phosphoribosyl-AMP cyclohydrolase [Pseudochrobactrum sp. AO18b].	48.62	109	54	1	19	125	26	134	2e-28	112
rs:WP_013335720	phosphoribosyl-AMP cyclohydrolase [Vulcanisaeta distributa].	58.62	87	36	0	26	112	34	120	2e-28	112
rs:WP_038358430	phosphoribosyl-AMP cyclohydrolase [Bosea sp. UNC402CLCol].	51.55	97	45	1	19	113	22	118	2e-28	112
tr:D1JE95_9ARCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	54.35	92	42	0	22	113	4	95	2e-28	111
rs:WP_000803963	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	54.44	90	41	0	24	113	8	97	2e-28	110
rs:WP_014108167	phosphoribosyl-AMP cyclohydrolase [Glaciecola nitratireducens].	50.55	91	45	0	24	114	18	108	2e-28	114
rs:WP_041623717	phosphoribosyl-AMP cyclohydrolase [Spirochaeta thermophila].	54.55	99	43	2	23	119	2	100	2e-28	111
rs:WP_020425605	hypothetical protein [Paenibacillus riograndensis].	52.08	96	46	0	18	113	19	114	2e-28	114
rs:WP_027200964	phosphoribosyl-ATP pyrophosphatase [Butyricimonas virosa].	51.02	98	48	0	14	111	3	100	2e-28	114
rs:WP_000803956	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacillus cereus group].	54.44	90	41	0	24	113	8	97	2e-28	110
rs:WP_025421668	phosphoribosyl-ATP pyrophosphatase [Sodalis praecaptivus].	48.11	106	55	0	23	128	16	121	2e-28	114
rs:WP_003727273	phosphoribosyl-AMP cyclohydrolase [Listeria monocytogenes].	49.47	95	48	0	24	118	9	103	2e-28	110
sp:HIS2_OCEIH	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	51.04	96	47	0	18	113	10	105	2e-28	114
rs:WP_027045895	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. URHC0008].	47.86	117	49	2	19	123	25	141	2e-28	112
rs:WP_013451584	phosphoribosyl-AMP cyclohydrolase [Calditerrivibrio nitroreducens].	50.55	91	45	0	23	113	15	105	2e-28	111
rs:WP_005545767	phosphoribosyl-ATP pyrophosphatase [Paenibacillus alvei].	45.79	107	53	1	18	124	16	117	2e-28	114
tr:K7YLX1_9PROT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	45.13	113	61	1	19	130	26	138	2e-28	112
rs:WP_043973052	phosphoribosyl-AMP cyclohydrolase [Novosphingobium sp. P6W].	49.06	106	53	1	19	123	18	123	2e-28	111
rs:WP_002464508	phosphoribosyl-AMP cyclohydrolase [Staphylococcus simiae].	52.75	91	43	0	24	114	11	101	2e-28	114
rs:WP_035662182	phosphoribosyl-ATP pyrophosphatase [Flavobacterium sp. EM1321].	48.15	108	53	1	11	118	1	105	2e-28	113
rs:WP_029965153	phosphoribosyl-AMP cyclohydrolase [Ensifer sp. USDA 6670].	50.49	103	50	1	19	120	32	134	2e-28	112
rs:WP_046626259	phosphoribosyl-AMP cyclohydrolase [Neorhizobium galegae].	47.01	117	60	1	17	131	22	138	2e-28	112
rs:WP_027215579	imidazole glycerol phosphate synthase [Butyrivibrio fibrisolvens].	54.44	90	41	0	25	114	1	90	2e-28	113
rs:WP_026613811	phosphoribosyl-AMP cyclohydrolase [Ensifer sp. TW10].	50.44	113	52	2	17	125	22	134	3e-28	112
rs:WP_007760069	phosphoribosyl-AMP cyclohydrolase [Rhizobium sp. CF080].	47.01	117	60	1	17	131	22	138	3e-28	112
rs:WP_028859574	phosphoribosyl-AMP cyclohydrolase [Psychrobacter phenylpyruvicus].	53.61	97	44	1	18	113	16	112	3e-28	115
rs:WP_046607029	phosphoribosyl-AMP cyclohydrolase [Neorhizobium galegae].	47.01	117	60	1	17	131	22	138	3e-28	112
rs:WP_041004398	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. SOD10].	47.01	117	50	2	19	123	25	141	3e-28	112
tr:E0PES2_STREI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	56.04	91	40	0	24	114	15	105	3e-28	110
rs:WP_021732707	phosphoribosyl-AMP cyclohydrolase [Lactobacillus plantarum].	51.06	94	46	0	24	117	10	103	3e-28	110
rs:WP_040477265	phosphoribosyl-ATP pyrophosphatase [Halanaerobium saccharolyticum].	45.05	111	56	1	11	121	1	106	3e-28	114
rs:WP_035329282	phosphoribosyl-ATP pyrophosphatase [Bacillus firmus].	50.53	95	47	0	18	112	6	100	3e-28	114
rs:WP_009194877	phosphoribosyl-ATP pyrophosphatase [Cesiribacter andamanensis].	53.93	89	41	0	24	112	15	103	3e-28	113
rs:WP_008425563	phosphoribosyl-AMP cyclohydrolase [Clostridium sp. Maddingley MBC34-26].	55.56	90	40	0	24	113	17	106	3e-28	110
rs:WP_021495256	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillales].	47.22	108	57	0	18	125	7	114	3e-28	113
rs:WP_027217361	imidazole glycerol phosphate synthase [Butyrivibrio fibrisolvens].	54.44	90	41	0	25	114	1	90	3e-28	113
rs:WP_014665504	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. JS].	54.84	93	42	0	20	112	9	101	3e-28	114
rs:WP_004207696	phosphoribosyl-AMP cyclohydrolase [Sphingobium yanoikuyae].	51.52	99	48	0	15	113	10	108	3e-28	111
tr:A0A090FLU2_9RHIZ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	47.01	117	50	2	19	123	34	150	3e-28	112
rs:WP_035506060	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Halobacillus].	49.47	95	48	0	18	112	6	100	3e-28	113
sp:HIS3_BACC4	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	54.44	90	41	0	24	113	8	97	3e-28	110
rs:WP_027206041	imidazole glycerol phosphate synthase [Butyrivibrio fibrisolvens].	54.44	90	41	0	25	114	1	90	3e-28	113
rs:WP_044518444	phosphoribosyl-AMP cyclohydrolase [Mycobacterium septicum].	55.79	95	42	0	18	112	12	106	3e-28	111
rs:WP_017726312	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. L1(2012)].	50.00	102	49	1	11	112	1	100	3e-28	113
rs:WP_024443100	phosphoribosyl-AMP cyclohydrolase [Mycobacterium sp. UM_WGJ].	55.79	95	42	0	18	112	11	105	3e-28	111
tr:J0B206_ALCFA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.88	104	47	1	19	120	36	139	3e-28	112
rs:WP_043930298	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. EB01].	49.00	100	51	0	13	112	1	100	3e-28	114
rs:WP_033162352	phosphoribosyl-AMP cyclohydrolase [Sharpea azabuensis].	47.06	102	54	0	24	125	10	111	3e-28	111
rs:WP_038435880	phosphoribosyl-AMP cyclohydrolase [Mycobacterium tuberculosis].	52.63	95	45	0	18	112	11	105	3e-28	111
rs:WP_028908781	phosphoribosyl-ATP pyrophosphatase [Prevotella sp. AGR2160].	53.61	97	44	1	17	112	2	98	3e-28	114
tr:X1FXB0_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S01480 {ECO:0000313|EMBL:GAH50291.1};	56.10	82	36	0	40	121	1	82	3e-28	110
tr:A0A075YVK2_MYCTX	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	51.52	99	48	0	18	116	11	109	3e-28	111
rs:WP_012163480	phosphoribosyl-AMP cyclohydrolase [Acaryochloris marina].	51.40	107	50	1	19	123	23	129	3e-28	112
rs:WP_021684053	phosphoribosyl-ATP diphosphatase [Selenomonas sp. oral taxon 892].	48.04	102	52	1	11	112	1	101	3e-28	114
rs:WP_041972851	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptococcus].	56.04	91	40	0	24	114	13	103	3e-28	110
rs:WP_025807151	phosphoribosyl-ATP pyrophosphatase [Bacillus licheniformis].	53.68	95	44	0	18	112	7	101	3e-28	113
rs:WP_042644277	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. ORS3359].	53.00	100	45	1	19	116	25	124	3e-28	112
rs:WP_017864485	histidine biosynthesis bifunctional protein HisIE [Lactococcus lactis].	53.19	94	44	0	20	113	5	98	3e-28	114
rs:WP_018127694	hypothetical protein [Balneola vulgaris].	50.00	110	53	1	19	126	24	133	3e-28	112
rs:WP_041895201	phosphoribosyl-AMP cyclohydrolase [Clostridium beijerinckii].	53.33	90	42	0	24	113	17	106	3e-28	110
rs:WP_041778592	phosphoribosyl-AMP cyclohydrolase, partial [Beijerinckia indica].	50.98	102	48	1	17	116	22	123	3e-28	111
rs:WP_008276175	phosphoribosyl-AMP cyclohydrolase [Cyanothece sp. CCY0110].	49.07	108	53	1	19	124	23	130	3e-28	112
rs:WP_009201383	phosphoribosyl-ATP pyrophosphatase [Anaerobaculum hydrogeniformans].	48.11	106	55	0	14	119	3	108	3e-28	113
rs:WP_006744322	phosphoribosyl-ATP pyrophosphatase [Bacteroides coprosuis].	47.22	108	53	1	9	112	247	354	3e-28	117
rs:WP_044631927	phosphoribosyl-ATP pyrophosphatase [Tamlana sedimentorum].	50.00	94	47	0	18	111	3	96	3e-28	113
rs:WP_006532644	phosphoribosyl-AMP cyclohydrolase [Streptococcus infantarius].	56.04	91	40	0	24	114	13	103	3e-28	110
rs:WP_045518128	phosphoribosyl-ATP pyrophosphatase [Bacillus niacini].	51.04	96	47	0	17	112	2	97	3e-28	113
rs:WP_025023165	phosphoribosyl-AMP cyclohydrolase [Lactobacillus nodensis].	52.08	96	46	0	24	119	12	107	3e-28	110
rs:WP_041967457	phosphoribosyl-ATP pyrophosphatase [Bacillus selenatarsenatis].	54.74	95	43	0	18	112	6	100	3e-28	114
rs:WP_003371351	phosphoribosyl-AMP cyclohydrolase [Clostridium botulinum].	51.11	90	44	0	24	113	17	106	3e-28	110
rs:WP_015293068	phosphoribosyl-AMP cyclohydrolase [Mycobacterium canettii].	52.63	95	45	0	18	112	11	105	3e-28	110
rs:WP_035345481	phosphoribosyl-ATP pyrophosphatase [Bacillus hemicellulosilyticus].	51.58	95	46	0	18	112	6	100	3e-28	113
rs:WP_023500620	phosphoribosyl-AMP cyclohydrolase [uncultured archaeon A07HB70].	56.82	88	38	0	26	113	16	103	3e-28	111
rs:WP_008809341	phosphoribosyl-AMP cyclohydrolase [Streptococcus sp. 2_1_36FAA].	52.04	98	47	0	21	118	10	107	3e-28	110
rs:WP_036574032	phosphoribosyl-AMP cyclohydrolase [Olsenella uli].	51.04	96	47	0	18	113	1	96	3e-28	110
rs:WP_023810481	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. L2C084A000].	48.72	117	48	2	19	123	25	141	3e-28	112
rs:WP_037615595	phosphoribosyl-AMP cyclohydrolase [Streptococcus sinensis].	52.04	98	47	0	21	118	10	107	3e-28	110
rs:WP_002900085	phosphoribosyl-AMP cyclohydrolase [Streptococcus sanguinis].	52.04	98	47	0	21	118	10	107	3e-28	110
rs:WP_002897324	phosphoribosyl-AMP cyclohydrolase [Streptococcus sanguinis].	54.84	93	42	0	21	113	10	102	3e-28	110
rs:WP_039319965	phosphoribosyl-AMP cyclohydrolase [Mycobacterium setense].	55.79	95	42	0	18	112	11	105	3e-28	110
rs:WP_029284616	phosphoribosyl-ATP pyrophosphatase [Bacillus indicus].	49.49	99	50	0	14	112	2	100	3e-28	113
rs:WP_045837904	phosphoribosyl-AMP cyclohydrolase [Hyphomicrobium sp. 99].	52.53	99	45	1	20	116	27	125	3e-28	112
rs:WP_045431811	phosphoribosyl-ATP diphosphatase [bacterium UASB270].	48.70	115	52	2	16	130	230	337	3e-28	116
rs:WP_027307335	phosphoribosyl-AMP cyclohydrolase [Candidatus Pelagibacter ubique].	48.60	107	54	1	19	124	20	126	3e-28	112
tr:D9T636_MICAI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00006950}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	52.53	99	47	0	16	114	335	433	3e-28	117
rs:WP_009595677	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. HGF5].	50.52	97	48	0	18	114	18	114	3e-28	114
rs:WP_036662822	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. FSL H8-457].	46.67	105	56	0	18	122	18	122	3e-28	114
tr:W7T0V3_9PSEU	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	56.84	95	41	0	18	112	13	107	4e-28	111
rs:WP_041164852	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium opportunistum].	47.01	117	50	2	19	123	25	141	4e-28	112
rs:WP_022144424	phosphoribosyl-AMP cyclohydrolase [Ruminococcus sp. CAG:563].	48.00	100	52	0	13	112	2	101	4e-28	113
rs:WP_022771667	phosphoribosyl-AMP cyclohydrolase [Candidatus Symbiobacter mobilis].	47.66	107	52	1	18	120	14	120	4e-28	111
rs:WP_046301194	phosphoribosyl-AMP cyclohydrolase [Mycobacterium sp. UM_Kg27].	55.79	95	42	0	18	112	11	105	4e-28	110
rs:WP_013531983	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mesorhizobium].	50.00	112	52	2	19	126	25	136	4e-28	112
rs:WP_027167333	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. WSM3224].	55.00	100	43	1	19	116	25	124	4e-28	112
tr:F7Y4S3_MESOW	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	47.01	117	50	2	19	123	34	150	4e-28	112
tr:E0RR16_SPITD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	54.55	99	43	2	23	119	21	119	4e-28	111
rs:WP_002904741	phosphoribosyl-AMP cyclohydrolase [Streptococcus sanguinis].	52.04	98	47	0	21	118	10	107	4e-28	110
rs:WP_013933428	phosphoribosyl-AMP cyclohydrolase [Zymomonas mobilis].	52.04	98	47	0	20	117	15	112	4e-28	111
rs:WP_017663958	hypothetical protein [Porphyrobacter sp. AAP82].	48.51	101	52	0	19	119	20	120	4e-28	111
rs:WP_034319523	phosphoribosyl-ATP diphosphatase [Helicobacter trogontum].	48.94	94	48	0	24	117	12	105	4e-28	114
rs:WP_023778770	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. LNHC221B00].	47.01	117	50	2	19	123	25	141	4e-28	112
rs:WP_043408786	phosphoribosyl-AMP cyclohydrolase [Mycobacterium rufum].	54.74	95	43	0	18	112	11	105	4e-28	110
rs:WP_005148975	phosphoribosyl-AMP cyclohydrolase [Mycobacterium rhodesiae].	54.74	95	43	0	18	112	11	105	4e-28	110
rs:WP_039167695	phosphoribosyl-AMP cyclohydrolase [Leisingera sp. ANG-M1].	53.33	105	47	1	19	121	26	130	4e-28	112
rs:WP_013315361	phosphoribosyl-AMP cyclohydrolase [Candidatus Zinderia insecticola].	43.88	98	54	1	20	116	11	108	4e-28	110
rs:WP_023791504	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. LNHC209A00].	47.86	117	49	2	19	123	25	141	4e-28	112
rs:WP_015010077	phosphoribosyl-ATP pyrophosphatase [Amphibacillus xylanus].	47.57	103	54	0	24	126	8	110	4e-28	113
tr:B2IBC7_BEII9	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	50.98	102	48	1	17	116	24	125	4e-28	112
rs:WP_020671563	phosphoribosyl-AMP cyclohydrolase [Amycolatopsis nigrescens].	56.70	97	42	0	18	114	12	108	4e-28	110
rs:WP_042629702	phosphoribosyl-AMP cyclohydrolase [Mycobacterium tuberculosis].	52.63	95	45	0	18	112	11	105	4e-28	110
rs:WP_026035959	phosphoribosyl-AMP cyclohydrolase [Cupriavidus sp. BIS7].	48.48	99	50	1	16	113	7	105	4e-28	111
rs:WP_022080326	phosphoribosyl-AMP cyclohydrolase [Ruminococcus sp. CAG:488].	48.00	100	52	0	13	112	2	101	4e-28	113
rs:WP_037948241	phosphoribosyl-ATP diphosphatase [Sulfuricurvum sp. MLSB].	52.63	95	45	0	25	119	13	107	4e-28	114
sp:HIS3_MYCBO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.63	95	45	0	18	112	11	105	4e-28	110
rs:WP_026381238	phosphoribosyl-AMP cyclohydrolase [Afifella pfennigii].	48.72	117	54	2	2	117	13	124	4e-28	112
rs:WP_021690509	phosphoribosyl-AMP cyclohydrolase [Novosphingobium tardaugens].	47.52	101	53	0	19	119	3	103	4e-28	110
rs:WP_042243511	phosphoribosyl-ATP pyrophosphatase [Jejuia pallidilutea].	44.92	118	54	2	17	123	2	119	4e-28	113
rs:WP_023770009	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. LNHC229A00].	47.86	117	49	2	19	123	25	141	4e-28	112
tr:J9GQX2_9ZZZZ	SubName: Full=Phosphoribosyl-ATP diphosphatase {ECO:0000313|EMBL:EJX10772.1};	52.94	102	42	2	11	112	3	98	4e-28	113
rs:WP_025143117	phosphoribosyl-ATP pyrophosphatase [Sphingobacterium sp. H1ai].	49.52	105	52	1	11	114	1	105	4e-28	113
rs:WP_047003505	phosphoribosyl-AMP cyclohydrolase [Erythrobacter sp. KA37].	50.53	95	47	0	19	113	16	110	4e-28	110
rs:WP_023916399	phosphoribosyl-AMP cyclohydrolase [Streptococcus sanguinis].	51.02	98	48	0	21	118	10	107	4e-28	110
rs:WP_019737750	phosphoribosyl-AMP cyclohydrolase [Mycobacterium avium].	55.79	95	42	0	18	112	11	105	4e-28	110
rs:WP_042532266	phosphoribosyl-ATP pyrophosphatase [Oceanobacillus oncorhynchi].	48.98	98	50	0	17	114	4	101	4e-28	113
rs:WP_032086639	phosphoribosyl-ATP pyrophosphatase [Bacillus aquimaris].	50.93	108	50	1	16	120	8	115	4e-28	113
rs:WP_029962179	phosphoribosyl-AMP cyclohydrolase [Ensifer sp. USDA 6670].	52.94	102	46	1	17	116	22	123	4e-28	111
rs:WP_002909424	phosphoribosyl-AMP cyclohydrolase [Streptococcus sanguinis].	51.96	102	46	1	21	119	10	111	4e-28	110
tr:K1Y403_9BACT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	42.61	115	66	0	16	130	6	120	4e-28	111
rs:WP_042704632	phosphoribosyl-AMP cyclohydrolase [Methanobrevibacter arboriphilus].	51.61	93	45	0	21	113	10	102	4e-28	111
rs:WP_042350732	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. G2(2012b)].	51.58	95	46	0	18	112	6	100	4e-28	113
rs:WP_014213431	phosphoribosyl-AMP cyclohydrolase [Mycobacterium rhodesiae].	54.64	97	44	0	16	112	10	106	4e-28	110
rs:WP_014457832	phosphoribosyl-ATP pyrophosphatase [Bacillus megaterium].	50.00	96	48	0	17	112	5	100	4e-28	113
tr:D5V3C2_ARCNC	RecName: Full=GTP cyclohydrolase II {ECO:0000256|SAAS:SAAS00129532}; EC=3.5.4.25 {ECO:0000256|SAAS:SAAS00129532};	50.00	104	45	2	11	113	3	100	4e-28	115
rs:WP_045625046	phosphoribosyl-AMP cyclohydrolase [Lactobacillus paracasei].	49.06	106	53	1	17	121	3	108	4e-28	110
rs:WP_003137396	phosphoribosyl-AMP cyclohydrolase [Lactococcus raffinolactis].	53.76	93	43	0	24	116	21	113	4e-28	110
rs:WP_036468823	phosphoribosyl-AMP cyclohydrolase [Mycobacterium triplex].	54.74	95	43	0	18	112	11	105	4e-28	110
rs:WP_041424625	phosphoribosyl-AMP cyclohydrolase, partial [Thermobaculum terrenum].	49.51	103	51	1	18	119	2	104	4e-28	110
rs:WP_016077938	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	54.44	90	41	0	24	113	8	97	4e-28	110
rs:WP_002924251	phosphoribosyl-AMP cyclohydrolase [Streptococcus sanguinis].	52.04	98	47	0	21	118	10	107	4e-28	110
sp:HIS3_STRSV	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.04	98	47	0	21	118	10	107	4e-28	110
rs:WP_037507429	phosphoribosyl-AMP cyclohydrolase [Sphingobium yanoikuyae].	51.52	99	48	0	15	113	10	108	4e-28	110
tr:X8HWN4_9ACTN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	48.51	101	52	0	13	113	26	126	4e-28	111
rs:WP_046626509	phosphoribosyl-AMP cyclohydrolase [Neorhizobium galegae].	47.01	117	60	1	17	131	22	138	4e-28	111
rs:WP_020103229	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mycobacterium].	54.74	95	43	0	18	112	11	105	5e-28	110
rs:WP_014075673	phosphoribosyl-AMP cyclohydrolase [Sphingobium sp. SYK-6].	46.77	124	60	2	1	123	1	119	5e-28	110
rs:WP_015882719	phosphoribosyl-AMP cyclohydrolase [Beutenbergia cavernae].	53.68	95	44	0	18	112	15	109	5e-28	110
rs:WP_018986660	phosphoribosyl-AMP cyclohydrolase [Methylophilus methylotrophus].	46.36	110	57	2	18	126	7	115	5e-28	110
rs:WP_028949472	phosphoribosyl-AMP cyclohydrolase [Sulfolobales archaeon Acd1].	52.69	93	44	0	26	118	24	116	5e-28	110
rs:WP_015118370	phosphoribosyl-AMP cyclohydrolase [Rivularia sp. PCC 7116].	50.00	108	52	1	19	124	23	130	5e-28	112
rs:WP_042479912	phosphoribosyl-AMP cyclohydrolase [Alcaligenes faecalis].	53.33	105	47	1	19	121	19	123	5e-28	111
sp:HIS2_WOLSU	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	51.61	93	45	0	25	117	15	107	5e-28	113
tr:F7KAG3_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	51.38	109	47	1	18	126	229	331	5e-28	116
rs:WP_028965932	phosphoribosyl-AMP cyclohydrolase [Sphingomonas phyllosphaerae].	49.06	106	53	1	19	123	14	119	5e-28	110
rs:WP_012861629	phosphoribosyl-ATP pyrophosphatase [Sebaldella termitidis].	47.47	99	52	0	18	116	10	108	5e-28	113
tr:V8LVN4_STRTR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	49.07	108	49	1	11	118	6	107	5e-28	110
rs:WP_029071241	imidazole glycerol phosphate synthase [Kandleria vitulina].	53.68	95	43	1	20	113	5	99	5e-28	113
rs:WP_007691373	phosphoribosyl-AMP cyclohydrolase [Halococcus hamelinensis].	53.54	99	46	0	15	113	9	107	5e-28	110
rs:WP_014895051	phosphoribosyl-AMP cyclohydrolase [Candidatus Portiera aleyrodidarum].	45.54	112	61	0	12	123	22	133	5e-28	111
rs:WP_043817787	imidazole glycerol phosphate synthase [Deinococcus sp. 2009].	49.12	114	57	1	14	126	6	119	5e-28	113
sp:HIS3_AGRRK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	48.78	123	58	2	10	130	18	137	5e-28	111
rs:WP_023411023	hypothetical protein [uncultured Thiohalocapsa sp. PB-PSB1].	45.52	134	54	3	3	117	7	140	5e-28	112
rs:WP_016742309	phosphoribosyl-ATP pyrophosphatase [Brevibacillus brevis].	49.00	100	51	0	13	112	7	106	5e-28	113
rs:WP_002906296	phosphoribosyl-AMP cyclohydrolase [Streptococcus sanguinis].	52.04	98	47	0	21	118	10	107	5e-28	110
tr:X1DPG7_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_S19889 {ECO:0000313|EMBL:GAH10135.1}; Flags: Fragment;	49.48	97	49	0	17	113	21	117	5e-28	110
rs:WP_040265014	phosphoribosyl-ATP pyrophosphatase [Serratia symbiotica].	50.00	96	48	0	23	118	16	111	5e-28	112
rs:WP_016888376	phosphoribosyl-AMP cyclohydrolase [Mycobacterium abscessus].	53.68	95	44	0	18	112	12	106	5e-28	110
rs:WP_011643549	phosphoribosyl-AMP cyclohydrolase [Maricaulis maris].	52.48	101	47	1	13	112	2	102	5e-28	113
tr:K2F303_9BACT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	49.54	109	48	3	12	114	3	110	5e-28	110
rs:WP_015652632	phosphoribosyl-amp cyclohydrolase [uncultured Sulfuricurvum sp. RIFRC-1].	52.04	98	47	0	22	119	10	107	5e-28	113
rs:WP_046846246	phosphoribosyl-AMP cyclohydrolase [Hyphomicrobium sp. GJ21].	55.67	97	41	1	19	113	26	122	5e-28	111
tr:A0A0D3LKT3_9BACT	SubName: Full=Phosphoribosyl-ATP pyrophosphohydrolase {ECO:0000313|EMBL:AHM62463.1};	48.51	101	46	1	12	112	9	103	5e-28	112
rs:WP_044968306	hypothetical protein [Clostridiaceae bacterium MS3].	51.38	109	47	1	18	126	209	311	5e-28	116
rs:WP_026799981	phosphoribosyl-ATP pyrophosphatase [Pontibacillus halophilus].	49.49	99	50	0	18	116	6	104	5e-28	113
rs:WP_021777058	Arylsulfatase [alpha proteobacterium RS24].	50.45	111	51	2	19	125	23	133	5e-28	111
tr:M5EEZ6_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	45.19	104	57	0	18	121	13	116	5e-28	113
tr:X7YQI4_MYCXE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.74	95	43	0	18	112	11	105	5e-28	110
rs:WP_044638969	phosphoribosyl-ATP pyrophosphatase [Siansivirga zeaxanthinifaciens].	44.07	118	55	2	17	123	2	119	5e-28	112
rs:WP_039227129	imidazole glycerol phosphate synthase [Clostridium novyi].	53.33	90	42	0	24	113	262	351	5e-28	115
rs:WP_026559649	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. J37].	50.00	96	48	0	17	112	4	99	5e-28	112
rs:WP_007172966	phosphoribosyl-AMP cyclohydrolase [Prevotella bergensis].	50.00	102	45	1	11	112	3	98	5e-28	113
rs:WP_039314032	phosphoribosyl-AMP cyclohydrolase [Clostridium baratii].	48.45	97	49	1	18	113	9	105	6e-28	110
rs:WP_022336167	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [Firmicutes bacterium CAG:94].	50.49	103	51	0	11	113	248	350	6e-28	115
rs:WP_036175713	phosphoribosyl-ATP pyrophosphatase [Lysinibacillus massiliensis].	51.58	95	46	0	18	112	4	98	6e-28	113
rs:WP_040659078	phosphoribosyl-ATP pyrophosphatase [Oscillibacter ruminantium].	52.08	96	46	0	18	113	3	98	6e-28	113
rs:WP_039869036	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. FSL R7-0273].	50.52	97	48	0	17	113	11	107	6e-28	113
rs:WP_026807176	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Arcobacter].	50.55	91	45	0	24	114	14	104	6e-28	113
rs:WP_041286913	phosphoribosyl-AMP cyclohydrolase [Desulfomonile tiedjei].	56.04	91	39	1	24	113	11	101	6e-28	110
rs:WP_046611798	phosphoribosyl-AMP cyclohydrolase [Neorhizobium galegae].	47.01	117	60	1	17	131	22	138	6e-28	111
rs:WP_017008888	phosphoribosyl-AMP cyclohydrolase [Enterovibrio calviensis].	43.08	130	60	3	5	129	3	123	6e-28	113
rs:WP_034556774	phosphoribosyl-ATP diphosphatase [Helicobacter muridarum].	46.46	99	53	0	16	114	10	108	6e-28	113
rs:WP_005007397	phosphoribosyl-AMP cyclohydrolase [Nitrospina gracilis].	51.92	104	43	2	11	113	3	100	6e-28	110
rs:WP_027089308	imidazole glycerol phosphate synthase [[Clostridium] saccharogumia].	51.58	95	46	0	20	114	5	99	6e-28	113
rs:WP_013158582	phosphoribosyl-ATP pyrophosphatase [Meiothermus silvanus].	46.15	104	56	0	13	116	1	104	6e-28	113
rs:WP_036413288	phosphoribosyl-AMP cyclohydrolase [Mycobacterium gastri].	52.53	99	47	0	18	116	11	109	6e-28	110
rs:WP_039833566	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sonchi].	51.04	96	47	0	18	113	19	114	6e-28	113
rs:WP_019123318	phosphoribosyl-ATP pyrophosphatase [Brevibacillus massiliensis].	52.08	96	46	0	17	112	9	104	6e-28	113
rs:WP_043568664	phosphoribosyl-AMP cyclohydrolase, partial [Acaricomes phytoseiuli].	52.04	98	47	0	15	112	23	120	6e-28	110
rs:WP_047146243	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. LC103].	47.71	109	55	1	19	125	22	130	6e-28	111
rs:WP_019421948	hypothetical protein [Paenibacillus sp. OSY-SE].	50.00	96	48	0	18	113	17	112	6e-28	113
rs:WP_037586606	phosphoribosyl-AMP cyclohydrolase [Stenoxybacter acetivorans].	48.08	104	53	1	17	119	14	117	6e-28	110
rs:WP_029335256	phosphoribosyl-AMP cyclohydrolase [Exiguobacterium aurantiacum].	51.61	93	45	0	25	117	1	93	6e-28	109
rs:WP_023949693	phosphoribosyl-AMP cyclohydrolase [Helicobacter fennelliae].	48.62	109	49	1	18	126	8	109	6e-28	113
rs:WP_026802948	phosphoribosyl-ATP diphosphatase [Arcobacter sp. AF1581].	50.55	91	45	0	24	114	14	104	6e-28	113
rs:WP_027452345	phosphoribosyl-ATP pyrophosphatase [Prevotella albensis].	52.22	90	43	0	23	112	9	98	6e-28	113
rs:WP_027036854	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium ciceri].	47.86	117	49	2	19	123	25	141	6e-28	111
rs:WP_031417799	phosphoribosyl-ATP pyrophosphatase [Lysinibacillus sphaericus].	43.24	111	63	0	18	128	5	115	6e-28	112
rs:WP_022047949	phosphoribosyl-ATP diphosphatase [Odoribacter laneus CAG:561].	51.02	98	48	0	14	111	2	99	6e-28	112
rs:WP_008520132	phosphoribosyl-AMP cyclohydrolase [alpha proteobacterium IMCC14465].	48.70	115	57	1	19	131	23	137	6e-28	111
rs:WP_009136843	phosphoribosyl-AMP cyclohydrolase [Odoribacter laneus].	51.02	98	48	0	14	111	2	99	6e-28	112
rs:WP_020402452	phosphoribosyl-AMP cyclohydrolase [Gracilimonas tropica].	50.49	103	49	1	19	119	24	126	6e-28	111
rs:WP_029606569	phosphoribosyl-AMP cyclohydrolase [Lactobacillus farciminis].	48.96	96	49	0	24	119	8	103	6e-28	109
rs:WP_000186704	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	50.00	90	45	0	24	113	8	97	6e-28	109
rs:WP_026591288	phosphoribosyl-AMP cyclohydrolase [Bacillus sp. UNC437CL72CviS29].	51.11	90	44	0	24	113	8	97	6e-28	109
rs:WP_038482600	phosphoribosyl-ATP pyrophosphatase [Bacillus lehensis].	49.48	97	49	0	16	112	2	98	6e-28	112
rs:WP_020398061	hypothetical protein [Kordiimonas gwangyangensis].	55.21	96	42	1	19	113	21	116	6e-28	110
rs:WP_018011113	phosphoribosyl-AMP cyclohydrolase [Sinorhizobium medicae].	52.94	102	46	1	17	116	23	124	6e-28	111
rs:WP_022311444	histidine biosynthesis protein HisIE [Prevotella sp. CAG:474].	50.00	104	46	1	9	112	2	99	6e-28	112
tr:A0A085F7X7_9BRAD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	50.00	112	51	2	19	125	22	133	6e-28	110
rs:WP_047184961	phosphoribosyl-ATP pyrophosphatase [Bacilli bacterium VT-13-104].	46.79	109	57	1	13	120	1	109	6e-28	112
rs:WP_028254544	hypothetical protein [Veillonella magna].	52.08	96	46	0	18	113	13	108	7e-28	113
tr:L0NEC4_RHISP	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	48.28	116	54	2	20	129	25	140	7e-28	111
rs:WP_035435280	phosphoribosyl-AMP cyclohydrolase [Bacillus sp. UNC322MFChir4.1].	52.69	93	44	0	24	116	8	100	7e-28	109
rs:WP_028066278	phosphoribosyl-ATP diphosphatase [Solirubrobacter soli].	48.04	102	53	0	13	114	1	102	7e-28	112
rs:WP_045683846	phosphoribosyl-AMP cyclohydrolase [Martelella endophytica].	51.82	110	49	2	15	120	19	128	7e-28	111
rs:WP_024029106	phosphoribosyl-AMP cyclohydrolase [Bacillus vireti].	52.08	96	46	0	17	112	2	97	7e-28	112
rs:WP_025765812	phosphoribosyl-AMP cyclohydrolase [Dehalococcoidia bacterium Dsc1].	47.00	100	53	0	18	117	1	100	7e-28	109
rs:WP_007394882	phosphoribosyl-AMP cyclohydrolase [Psychrobacter sp. 1501(2011)].	51.55	97	46	1	18	113	34	130	7e-28	115
rs:WP_003738249	phosphoribosyl-AMP cyclohydrolase [Listeria monocytogenes].	49.47	95	48	0	24	118	9	103	7e-28	109
rs:WP_021909794	phosphoribosyl-ATP diphosphatase [Prevotella sp. CAG:755].	50.98	102	44	1	11	112	4	99	7e-28	112
rs:WP_003532532	hypothetical protein [[Clostridium] leptum].	53.68	95	44	0	20	114	246	340	7e-28	115
rs:WP_044220388	phosphoribosyl-ATP pyrophosphatase [Phaeodactylibacter xiamenensis].	49.02	102	51	1	11	111	1	102	7e-28	112
tr:A6WC94_KINRD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	61.18	85	33	0	28	112	3	87	7e-28	109
rs:WP_044622820	phosphoribosyl-ATP pyrophosphatase [Photobacterium gaetbulicola].	51.69	89	43	0	24	112	14	102	7e-28	112
tr:A0A0B7GP83_STRSA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	52.04	98	47	0	21	118	10	107	7e-28	110
rs:WP_026482783	phosphoribosyl-AMP cyclohydrolase [Alcaligenes faecalis].	52.38	105	48	1	19	121	36	140	7e-28	111
tr:V2Y4F8_9FIRM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	50.00	100	50	0	13	112	16	115	7e-28	114
rs:WP_002149506	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	54.44	90	41	0	24	113	8	97	7e-28	109
rs:WP_034994782	phosphoribosyl-AMP cyclohydrolase [Beijerinckia mobilis].	46.72	122	55	3	7	123	17	133	7e-28	110
rs:WP_024454017	phosphoribosyl-AMP cyclohydrolase [Mycobacterium sp. UM_RHS].	54.74	95	43	0	18	112	11	105	7e-28	110
rs:WP_023801042	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. L48C026A00].	47.01	117	50	2	19	123	25	141	7e-28	111
rs:WP_026699235	phosphoribosyl-ATP pyrophosphatase [Bacillus licheniformis].	52.63	95	45	0	18	112	7	101	7e-28	112
rs:WP_027156260	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. WSM2561].	47.01	117	50	2	19	123	25	141	7e-28	111
rs:WP_025649333	phosphoribosyl-ATP pyrophosphatase [Bacillus methylotrophicus].	51.58	95	46	0	18	112	7	101	7e-28	112
rs:WP_022237315	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [Clostridium leptum CAG:27].	53.68	95	44	0	20	114	246	340	7e-28	115
rs:WP_039239029	imidazole glycerol phosphate synthase [Clostridium novyi].	52.75	91	43	0	23	113	261	351	8e-28	115
rs:WP_016088718	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	53.33	90	42	0	24	113	8	97	8e-28	109
tr:D8PBZ0_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	48.54	103	52	1	18	119	1	103	8e-28	112
rs:WP_018473292	phosphoribosyl-AMP cyclohydrolase [Echinicola pacifica].	49.02	102	46	2	11	112	6	101	8e-28	112
rs:WP_004370476	phosphoribosyl-AMP cyclohydrolase [Prevotella oralis].	53.33	90	42	0	23	112	9	98	8e-28	112
rs:WP_026963302	phosphoribosyl-ATP pyrophosphatase [Alicyclobacillus pomorum].	52.00	100	48	0	22	121	21	120	8e-28	114
rs:WP_017795627	phosphoribosyl-ATP pyrophosphatase [Oceanobacillus kimchii].	51.04	96	47	0	18	113	10	105	8e-28	112
rs:WP_012257923	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Chloroflexus].	56.18	89	39	0	25	113	9	97	8e-28	112
rs:WP_047318110	phosphoribosyl-AMP cyclohydrolase [Mycobacterium heraklionense].	54.74	95	43	0	18	112	12	106	8e-28	110
rs:WP_027841800	phosphoribosyl-AMP cyclohydrolase [Mastigocoleus testarum].	50.00	108	52	1	19	124	23	130	8e-28	111
rs:WP_019378987	hypothetical protein [Virgibacillus halodenitrificans].	49.02	102	52	0	11	112	1	102	8e-28	112
rs:WP_039331484	phosphoribosyl-AMP cyclohydrolase [Novosphingobium subterraneum].	49.47	95	48	0	19	113	3	97	8e-28	109
rs:WP_020086447	hypothetical protein [Hyphomicrobium zavarzinii].	49.55	111	51	2	8	113	13	123	8e-28	110
rs:WP_002914872	phosphoribosyl-AMP cyclohydrolase [Streptococcus sanguinis].	51.02	98	48	0	21	118	10	107	8e-28	110
rs:WP_044983817	hypothetical protein [Lachnospiraceae bacterium 3_1_57FAA_CT1].	51.38	109	47	1	18	126	209	311	8e-28	115
rs:WP_002930874	phosphoribosyl-AMP cyclohydrolase [Streptococcus sanguinis].	52.04	98	47	0	21	118	10	107	8e-28	110
sp:HIS3_GEOLS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.00	98	48	1	23	119	10	107	8e-28	110
rs:WP_005829923	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillales].	48.62	109	55	1	17	124	10	118	8e-28	112
rs:WP_044511588	phosphoribosyl-AMP cyclohydrolase [Mycobacterium simiae].	53.68	95	44	0	18	112	12	106	8e-28	110
rs:WP_018662141	phosphoribosyl-ATP pyrophosphatase [Bacillus acidiproducens].	51.55	97	46	1	24	119	8	104	8e-28	112
rs:WP_013833599	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Novosphingobium].	49.49	99	50	0	19	117	18	116	8e-28	110
rs:WP_036480898	phosphoribosyl-AMP cyclohydrolase [Nitratireductor basaltis].	48.65	111	53	2	17	123	23	133	8e-28	110
rs:WP_039379563	phosphoribosyl-AMP cyclohydrolase [Mycobacterium setense].	55.79	95	42	0	18	112	11	105	9e-28	109
rs:WP_046075334	phosphoribosyl-ATP pyrophosphatase [Salinivibrio sp. KP-1].	53.33	90	42	0	23	112	15	104	9e-28	112
rs:WP_018913634	hypothetical protein [Thiomonas sp. FB-6].	46.73	107	53	1	17	119	9	115	9e-28	110
rs:WP_039193157	phosphoribosyl-AMP cyclohydrolase [Aureimonas altamirensis].	50.49	103	49	1	19	119	17	119	9e-28	110
rs:WP_008240952	phosphoribosyl-AMP cyclohydrolase [Imtechella halotolerans].	50.55	91	45	0	21	111	8	98	9e-28	112
rs:WP_004570679	phosphoribosyl-AMP cyclohydrolase [Polaribacter irgensii].	46.49	114	50	1	21	123	8	121	9e-28	112
rs:WP_025744690	phosphoribosyl-ATP pyrophosphatase [Salinivibrio costicola].	53.33	90	42	0	23	112	15	104	9e-28	112
rs:WP_035073966	phosphoribosyl-ATP pyrophosphatase [Anditalea andensis].	50.56	89	44	0	24	112	13	101	9e-28	112
rs:WP_044283332	phosphoribosyl-AMP cyclohydrolase [Candidatus Endolissoclinum faulkneri].	45.87	109	58	1	24	131	3	111	9e-28	109
rs:WP_041314930	phosphoribosyl-AMP cyclohydrolase [Saccharothrix espanaensis].	54.74	95	43	0	18	112	13	107	9e-28	110
rs:WP_022629093	phosphoribosyl-ATP pyrophosphatase [Bacillus marmarensis].	50.53	95	47	0	18	112	6	100	9e-28	112
tr:A5WHW8_PSYWF	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	54.74	95	42	1	20	113	27	121	9e-28	114
rs:WP_021022340	phosphoribosyl-AMP cyclohydrolase [Salinivibrio costicola].	53.33	90	42	0	23	112	15	104	9e-28	112
rs:WP_037163351	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Rhizobium].	46.90	113	58	1	20	130	25	137	9e-28	110
rs:WP_013679416	phosphoribosyl-AMP cyclohydrolase [Thermoproteus uzoniensis].	59.55	89	36	0	24	112	26	114	9e-28	110
rs:WP_035651320	hypothetical protein [Lachnospiraceae bacterium AD3010].	56.67	90	39	0	24	113	248	337	9e-28	115
rs:WP_025773268	hypothetical protein [Moorella thermoacetica].	51.55	97	47	0	18	114	9	105	9e-28	114
rs:WP_023720147	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. LSHC420B00].	47.01	117	50	2	19	123	25	141	9e-28	110
rs:WP_045724019	phosphoribosyl-AMP cyclohydrolase [Clostridium baratii].	48.45	97	49	1	18	113	10	106	9e-28	109
rs:WP_006390370	phosphoribosyl-AMP cyclohydrolase [Achromobacter insuavis].	50.00	102	50	1	19	119	31	132	9e-28	111
tr:A0A0C7N665_9THEO	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	52.58	97	46	0	18	114	9	105	9e-28	113
rs:WP_041773867	phosphoribosyl-AMP cyclohydrolase [Psychrobacter sp. PRwf-1].	54.74	95	42	1	20	113	14	108	1e-27	114
rs:WP_016505259	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	47.79	113	49	1	24	126	17	129	1e-27	112
rs:WP_026672308	phosphoribosyl-ATP pyrophosphatase [Bacillus bogoriensis].	50.53	95	47	0	18	112	6	100	1e-27	112
rs:WP_043767034	phosphoribosyl-AMP cyclohydrolase [Algiphilus aromaticivorans].	53.70	108	46	2	19	122	25	132	1e-27	110
rs:WP_024822502	phosphoribosyl-ATP pyrophosphatase [Aminobacterium mobile].	47.71	109	54	2	11	118	1	107	1e-27	112
rs:WP_008788337	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Coprobacillus].	47.66	107	53	1	24	130	10	113	1e-27	112
rs:WP_018376558	phosphoribosyl-AMP cyclohydrolase [Streptococcus orisratti].	50.54	93	46	0	22	114	11	103	1e-27	109
rs:WP_017152609	phosphoribosyl-AMP cyclohydrolase [Bacillus sp. FJAT-13831].	51.11	90	44	0	24	113	8	97	1e-27	109
rs:WP_013353734	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis group].	51.58	95	46	0	18	112	7	101	1e-27	112
rs:WP_022159706	phosphoribosyl-ATP pyrophosphatase [Odoribacter splanchnicus CAG:14].	52.04	98	47	0	14	111	2	99	1e-27	112
rs:WP_023252549	phosphoribosyl-AMP cyclohydrolase, partial [Salmonella enterica].	47.79	113	49	1	24	126	17	129	1e-27	111
rs:WP_024634116	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Paenibacillus].	54.95	91	41	0	24	114	26	116	1e-27	113
rs:WP_002086731	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacillus cereus group].	54.44	90	41	0	24	113	8	97	1e-27	109
sp:HIS3_BACCZ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.22	90	43	0	24	113	8	97	1e-27	109
rs:WP_028079340	phosphoribosyl-AMP cyclohydrolase [Solimonas soli].	52.94	102	47	1	19	119	25	126	1e-27	110
rs:WP_046365402	phosphoribosyl-AMP cyclohydrolase [Mycobacterium obuense].	54.74	95	43	0	18	112	11	105	1e-27	109
rs:WP_005661809	phosphoribosyl-ATP pyrophosphatase [Dethiosulfovibrio peptidovorans].	48.48	99	51	0	18	116	6	104	1e-27	112
rs:WP_045967344	phosphoribosyl-ATP pyrophosphatase [Flavobacterium sp. 316].	48.98	98	50	0	18	115	1	98	1e-27	112
rs:WP_023738995	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mesorhizobium].	44.36	133	58	3	3	123	13	141	1e-27	110
rs:WP_044447922	phosphoribosyl-ATP pyrophosphatase [Alteromonas australica].	53.33	90	42	0	24	113	18	107	1e-27	112
rs:WP_020887009	phosphoribosyl-AMP cyclohydrolase [Desulfovibrio alkalitolerans].	55.43	92	40	1	23	113	9	100	1e-27	110
rs:WP_045925884	phosphoribosyl-ATP pyrophosphatase [Bacillus siamensis].	47.22	108	57	0	18	125	7	114	1e-27	112
rs:WP_040605453	phosphoribosyl-AMP cyclohydrolase [Sandarakinorhabdus limnophila].	56.84	95	41	0	25	119	25	119	1e-27	110
rs:WP_016182401	phosphoribosyl-ATP diphosphatase [Enterococcus columbae].	48.51	101	52	0	18	118	7	107	1e-27	112
rs:WP_018464779	phosphoribosyl-AMP cyclohydrolase [Prevotella paludivivens].	50.00	102	45	2	11	112	3	98	1e-27	112
rs:WP_037223552	imidazole glycerol phosphate synthase [Richelia intracellularis].	50.51	99	48	1	18	115	18	116	1e-27	112
rs:WP_029190450	phosphoribosyl-AMP cyclohydrolase [Verrucomicrobium spinosum].	51.52	99	47	1	19	116	28	126	1e-27	110
rs:WP_044480757	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. GD11].	50.00	96	48	0	18	113	23	118	1e-27	112
sp:HIS3_BACCN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	51.11	90	44	0	24	113	8	97	1e-27	109
rs:WP_004608790	phosphoribosyl-ATP pyrophosphatase [[Clostridium] spiroforme].	50.00	98	49	0	20	117	5	102	1e-27	112
rs:WP_015266319	phosphoribosyl-ATP pyrophosphohydrolase [Echinicola vietnamensis].	47.17	106	50	2	7	112	2	101	1e-27	112
rs:WP_017930578	hypothetical protein [Robiginitomaculum antarcticum].	53.33	90	42	0	23	112	9	98	1e-27	112
rs:WP_008876204	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium metallidurans].	52.00	100	46	1	19	116	25	124	1e-27	110
sp:HIS3_BACAC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.22	90	43	0	24	113	8	97	1e-27	108
rs:WP_019388616	phosphoribosyl-AMP cyclohydrolase [Arenitalea lutea].	48.94	94	48	0	18	111	3	96	1e-27	112
sp:HIS3_BACAH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.22	90	43	0	24	113	8	97	1e-27	108
rs:WP_025737626	phosphoribosyl-AMP cyclohydrolase [Mycobacterium genavense].	54.74	95	43	0	18	112	11	105	1e-27	109
rs:WP_003438793	phosphoribosyl-AMP cyclohydrolase [Psychroflexus gondwanensis].	48.45	97	50	0	15	111	2	98	1e-27	112
rs:WP_036616408	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. FSL H7-689].	54.95	91	41	0	24	114	23	113	1e-27	112
rs:WP_015595652	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. 1NLA3E].	45.61	114	56	2	14	123	2	113	1e-27	112
rs:WP_020822819	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mycobacterium].	53.68	95	44	0	18	112	11	105	1e-27	109
rs:WP_007169684	phosphoribosyl-AMP cyclohydrolase [Mycobacterium parascrofulaceum].	53.68	95	44	0	18	112	11	105	1e-27	109
rs:WP_033675237	phosphoribosyl-AMP cyclohydrolase [Bacillus gaemokensis].	51.11	90	44	0	24	113	8	97	1e-27	108
rs:WP_002202658	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	54.44	90	41	0	24	113	8	97	1e-27	108
rs:WP_003321870	phosphoribosyl-ATP pyrophosphatase [Bacillus alcalophilus].	45.87	109	58	1	13	120	1	109	1e-27	112
rs:WP_017951464	hypothetical protein [Nitrospina sp. SCGC AAA288-L16].	50.00	108	52	2	24	130	10	116	1e-27	109
rs:WP_013668335	phosphoribosyl-AMP cyclohydrolase [Sphingobacterium sp. 21].	52.04	98	46	1	18	114	2	99	1e-27	111
rs:WP_013023627	phosphoribosyl-ATP pyrophosphatase [Helicobacter mustelae].	46.90	113	59	1	18	129	8	120	1e-27	112
rs:WP_045127248	phosphoribosyl-ATP pyrophosphatase [Photobacterium angustum].	46.73	107	56	1	23	129	13	118	1e-27	112
rs:WP_034561213	hypothetical protein, partial [Helicobacter macacae].	47.96	98	51	0	16	113	12	109	1e-27	113
rs:WP_009454647	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Alcaligenes].	52.38	105	48	1	19	121	36	140	1e-27	110
rs:WP_045151092	phosphoribosyl-ATP pyrophosphatase [Photobacterium angustum].	46.73	107	56	1	23	129	13	118	1e-27	112
rs:WP_016124314	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	53.33	90	42	0	24	113	8	97	1e-27	108
rs:WP_028412046	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. 278922_107].	50.00	96	48	0	17	112	5	100	1e-27	112
rs:WP_000803954	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	52.22	90	43	0	24	113	8	97	1e-27	108
rs:WP_040983802	phosphoribosyl-ATP pyrophosphatase [Oceanobacillus sp. S5].	48.98	98	50	0	17	114	2	99	1e-27	112
rs:WP_026081365	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. PAMC 26794].	54.95	91	41	0	24	114	23	113	1e-27	112
rs:WP_039498434	phosphoribosyl-ATP pyrophosphatase [Salmonella enterica].	47.79	113	49	1	24	126	8	120	1e-27	111
rs:WP_045635180	phosphoribosyl-AMP cyclohydrolase [Streptococcus mitis].	52.04	98	47	0	21	118	10	107	1e-27	109
rs:WP_008257763	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mycobacterium].	53.68	95	44	0	18	112	11	105	1e-27	109
rs:WP_045379233	phosphoribosyl-AMP cyclohydrolase [Mycobacterium kyorinense].	52.53	99	47	0	18	116	11	109	1e-27	109
rs:WP_027232534	phosphoribosyl-AMP cyclohydrolase [Phyllobacterium sp. UNC302MFCol5.2].	53.00	100	45	1	19	116	23	122	1e-27	110
rs:WP_019414290	hypothetical protein [Paenisporosarcina sp. TG20].	47.52	101	53	0	13	113	4	104	1e-27	112
rs:WP_014305903	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis group].	47.22	108	57	0	18	125	7	114	1e-27	112
rs:WP_003151472	phosphoribosyl-ATP pyrophosphatase [Bacillus amyloliquefaciens].	47.22	108	57	0	18	125	7	114	1e-27	112
rs:WP_036818110	phosphoribosyl-ATP pyrophosphatase [Photobacterium sanctipauli].	51.69	89	43	0	24	112	14	102	1e-27	112
rs:WP_036674761	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. FSL R5-192].	54.95	91	41	0	24	114	23	113	1e-27	112
rs:WP_003920347	phosphoribosyl-AMP cyclohydrolase [Mycobacterium xenopi].	53.68	95	44	0	18	112	11	105	1e-27	109
tr:J9GHX9_9ZZZZ	SubName: Full=Phosphoribosyl-ATP diphosphatase {ECO:0000313|EMBL:EJW99069.1};	49.02	102	46	2	11	112	3	98	1e-27	111
rs:WP_034592547	MULTISPECIES: imidazole glycerol phosphate synthase [Clostridiales].	50.98	102	44	1	25	126	1	96	1e-27	111
rs:WP_047005737	phosphoribosyl-AMP cyclohydrolase [Erythrobacter gangjinensis].	50.53	95	47	0	19	113	3	97	1e-27	109
rs:WP_005370611	phosphoribosyl-AMP cyclohydrolase [Photobacterium angustum].	46.73	107	56	1	23	129	13	118	1e-27	112
rs:WP_040281812	phosphoribosyl-ATP pyrophosphatase [Psychroserpens damuponensis].	51.65	91	44	0	24	114	10	100	1e-27	111
rs:WP_003469607	phosphoribosyl-AMP cyclohydrolase [Xanthomonas translucens].	50.50	101	49	1	13	112	21	121	1e-27	112
rs:WP_041502409	phosphoribosyl-ATP pyrophosphatase [Sanguibacteroides justesenii].	46.15	117	61	1	13	129	2	116	1e-27	111
rs:WP_045063983	phosphoribosyl-ATP pyrophosphatase [Photobacterium leiognathi].	46.73	107	56	1	23	129	13	118	1e-27	112
rs:WP_029367138	phosphoribosyl-AMP cyclohydrolase [Mycobacterium sp. UM_WWY].	54.74	95	43	0	18	112	12	106	1e-27	109
rs:WP_018337072	phosphoribosyl-AMP cyclohydrolase [Butyricimonas synergistica].	51.52	99	48	0	13	111	2	100	1e-27	111
rs:WP_013059715	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillus].	50.00	96	48	0	17	112	5	100	1e-27	111
rs:WP_000954825	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	47.79	113	49	1	24	126	17	129	1e-27	111
rs:WP_036395351	phosphoribosyl-AMP cyclohydrolase [Mycobacterium kansasii].	53.68	95	44	0	18	112	11	105	1e-27	109
rs:WP_043237295	phosphoribosyl-AMP cyclohydrolase, partial [Bosea sp. LC85].	52.58	97	44	1	19	113	22	118	2e-27	109
rs:WP_016092996	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	53.33	90	42	0	24	113	8	97	2e-27	108
tr:W4ADV7_9BACL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	54.95	91	41	0	24	114	26	116	2e-27	112
rs:WP_023821421	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. L2C054A000].	47.01	117	50	2	19	123	25	141	2e-27	110
tr:D4KDD0_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	54.95	91	40	1	22	112	2	91	2e-27	112
rs:WP_018703010	MULTISPECIES: hypothetical protein [Veillonellaceae].	51.49	101	49	0	18	118	6	106	2e-27	112
rs:WP_026509283	MULTISPECIES: imidazole glycerol phosphate synthase [Butyrivibrio].	50.00	90	45	0	25	114	1	90	2e-27	111
rs:WP_016506743	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	47.79	113	49	1	24	126	17	129	2e-27	111
rs:WP_042708559	phosphoribosyl-AMP cyclohydrolase [Methanobrevibacter wolinii].	44.14	111	61	1	21	131	10	119	2e-27	109
rs:WP_041504772	phosphoribosyl-ATP pyrophosphatase [Sanguibacteroides justesenii].	46.15	117	61	1	13	129	2	116	2e-27	111
rs:WP_001528427	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	47.79	113	49	1	24	126	17	129	2e-27	111
rs:WP_040375815	phosphoribosyl-ATP pyrophosphatase [Bacillus psychrosaccharolyticus].	49.47	95	48	0	18	112	6	100	2e-27	111
rs:WP_013085394	phosphoribosyl-ATP pyrophosphatase [Bacillus megaterium].	50.00	96	48	0	17	112	5	100	2e-27	111
gpu:CP008714_1400	phosphoribosyl-ATP pyrophosphatase [Xanthomonas translucens pv. undulosa]	50.50	101	49	1	13	112	1	101	2e-27	111
rs:WP_045291656	phosphoribosyl-ATP pyrophosphatase [Bacillus aryabhattai].	50.00	96	48	0	17	112	5	100	2e-27	111
rs:WP_023667623	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mesorhizobium].	52.00	100	46	1	19	116	25	124	2e-27	110
rs:WP_040954216	phosphoribosyl-ATP pyrophosphatase [Virgibacillus sp. SK37].	47.27	110	57	1	11	119	1	110	2e-27	112
rs:WP_028043285	imidazole glycerol phosphate synthase [Candidatus Stoquefichus massiliensis].	52.69	93	44	0	24	116	10	102	2e-27	112
rs:WP_007371298	phosphoribosyl-AMP cyclohydrolase [Kosakonia radicincitans].	52.81	89	42	0	24	112	17	105	2e-27	111
rs:WP_043953064	phosphoribosyl-ATP pyrophosphatase [Enterobacter sp. YD4].	52.81	89	42	0	24	112	17	105	2e-27	111
rs:WP_014119991	phosphoribosyl-ATP pyrophosphatase [Oscillibacter valericigenes].	51.55	97	47	0	18	114	3	99	2e-27	111
rs:WP_033575194	phosphoribosyl-ATP pyrophosphatase [Bacillus amyloliquefaciens].	46.30	108	58	0	18	125	7	114	2e-27	111
rs:WP_016765867	phosphoribosyl-ATP pyrophosphatase [Bacillus megaterium].	50.00	96	48	0	17	112	5	100	2e-27	111
rs:WP_005689354	phosphoribosyl-AMP cyclohydrolase [Lactobacillus rhamnosus].	51.55	97	46	1	18	113	4	100	2e-27	108
rs:WP_013612294	phosphoribosyl-AMP cyclohydrolase [Odoribacter splanchnicus].	52.04	98	47	0	14	111	2	99	2e-27	111
rs:WP_046450766	phosphoribosyl-ATP pyrophosphatase [Odoribacter sp. N54.MGS-14].	52.04	98	47	0	14	111	2	99	2e-27	111
rs:WP_002158666	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	53.33	90	42	0	24	113	8	97	2e-27	108
rs:WP_015317576	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium australicum].	47.01	117	50	2	19	123	25	141	2e-27	110
rs:WP_023753341	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mesorhizobium].	52.00	100	46	1	19	116	25	124	2e-27	110
rs:WP_032281133	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	53.93	89	41	0	24	112	13	101	2e-27	111
tr:G5NVH3_SALET	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	47.79	113	49	1	24	126	17	129	2e-27	111
rs:WP_023204341	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	47.79	113	49	1	24	126	17	129	2e-27	111
sp:HIS2_SALTY	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	47.79	113	49	1	24	126	17	129	2e-27	111
rs:WP_014644249	phosphoribosyl-ATP pyrophosphatase [Halobacillus halophilus].	47.47	99	52	0	14	112	2	100	2e-27	111
rs:WP_000186280	phosphoribosyl-AMP cyclohydrolase [Staphylococcus aureus].	50.54	93	46	0	24	116	11	103	2e-27	111
tr:I4BVC8_ANAMD	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	47.22	108	57	0	14	121	10	117	2e-27	111
rs:WP_000803970	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacillus cereus group].	51.61	93	45	0	24	116	8	100	2e-27	108
rs:WP_000954847	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	47.79	113	49	1	24	126	17	129	2e-27	111
tr:V8C8B5_9HELI	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	47.96	98	51	0	16	113	12	109	2e-27	113
rs:WP_046192144	phosphoribosyl-AMP cyclohydrolase [Sphingomonas sp. SRS2].	48.48	99	51	0	19	117	18	116	2e-27	109
rs:WP_000954845	histidine biosynthesis bifunctional protein HisIE [Salmonella enterica].	47.79	113	49	1	24	126	17	129	2e-27	111
rs:WP_043398474	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mycobacterium].	53.68	95	44	0	18	112	11	105	2e-27	108
rs:WP_035268024	phosphoribosyl-AMP cyclohydrolase [Alcaligenes faecalis].	52.38	105	48	1	19	121	36	140	2e-27	110
rs:WP_029206381	phosphoribosyl-AMP cyclohydrolase [alpha proteobacterium SCGC AAA288-G21].	50.00	98	48	1	17	113	18	115	2e-27	110
rs:WP_017441797	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	47.79	113	49	1	24	126	17	129	2e-27	111
rs:WP_023183259	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	47.79	113	49	1	24	126	17	129	2e-27	111
rs:WP_046977507	phosphoribosyl-ATP pyrophosphatase [Xanthomonas hyacinthi].	49.50	101	50	1	13	112	16	116	2e-27	111
rs:WP_039096282	phosphoribosyl-AMP cyclohydrolase [Kirrobacter mercurialis].	48.48	99	51	0	19	117	20	118	2e-27	109
rs:WP_023245865	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	47.79	113	49	1	24	126	17	129	2e-27	111
rs:WP_029618139	phosphoribosyl-AMP cyclohydrolase [Rhizobium sp. MGL06].	46.90	113	58	1	20	130	25	137	2e-27	110
rs:WP_000954846	histidine biosynthesis bifunctional protein HisIE [Salmonella enterica].	47.79	113	49	1	24	126	17	129	2e-27	111
rs:WP_040468753	phosphoribosyl-AMP cyclohydrolase [Lactobacillus gastricus].	51.52	99	47	1	19	117	4	101	2e-27	108
rs:WP_032288224	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	53.93	89	41	0	24	112	13	101	2e-27	111
rs:WP_042982725	phosphoribosyl-AMP cyclohydrolase [Bacillus mycoides].	52.22	90	43	0	24	113	8	97	2e-27	108
rs:WP_008406412	phosphoribosyl-ATP pyrophosphatase [Bacillus isronensis].	47.57	103	53	1	17	118	2	104	2e-27	111
rs:WP_016429092	phosphoribosyl-ATP diphosphatase [Paenisporosarcina sp. HGH0030].	50.52	97	48	0	17	113	8	104	2e-27	111
rs:WP_029607181	phosphoribosyl-AMP cyclohydrolase [Lactobacillus rhamnosus].	51.55	97	46	1	18	113	4	100	2e-27	108
rs:WP_044390501	phosphoribosyl-ATP pyrophosphatase [Bacillus subterraneus].	53.12	96	45	0	17	112	5	100	2e-27	111
rs:WP_019881191	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Methylophilus].	50.00	98	48	1	24	120	13	110	2e-27	109
rs:WP_001750273	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	47.79	113	49	1	24	126	17	129	2e-27	111
rs:WP_034354931	imidazole glycerol phosphate synthase [Deinococcus phoenicis].	49.53	107	49	1	18	119	9	115	2e-27	112
rs:WP_028838229	phosphoribosyl-ATP pyrophosphatase [Thermomonas fusca].	49.07	108	54	1	13	119	2	109	2e-27	111
rs:WP_028753271	phosphoribosyl-AMP cyclohydrolase [Rhizobium leucaenae].	48.28	116	58	1	17	130	22	137	2e-27	110
rs:WP_011721170	MULTISPECIES: imidazole glycerol phosphate synthase [Clostridium].	52.75	91	43	0	23	113	261	351	2e-27	114
rs:WP_026375202	phosphoribosyl-ATP pyrophosphatase [Aestuariibacter salexigens].	50.52	97	44	1	24	120	18	110	2e-27	111
rs:WP_028093159	phosphoribosyl-AMP cyclohydrolase [Donghicola xiamenensis].	52.38	105	48	1	19	121	25	129	2e-27	110
rs:WP_033571315	phosphoribosyl-AMP cyclohydrolase [Lactobacillus rhamnosus].	51.55	97	46	1	18	113	4	100	2e-27	108
rs:WP_036399815	phosphoribosyl-AMP cyclohydrolase [Mycobacterium cosmeticum].	54.74	95	43	0	18	112	11	105	2e-27	108
rs:WP_041094876	phosphoribosyl-AMP cyclohydrolase [Lactobacillus hokkaidonensis].	50.00	98	49	0	22	119	9	106	2e-27	108
rs:WP_044338291	phosphoribosyl-ATP pyrophosphatase [Bacillus aquimaris].	47.96	98	51	0	16	113	8	105	2e-27	111
rs:WP_000803971	phosphoribosyl-AMP cyclohydrolase [Bacillus thuringiensis].	51.61	93	45	0	24	116	8	100	2e-27	108
rs:WP_000954849	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	47.79	113	49	1	24	126	17	129	2e-27	111
rs:WP_037488658	phosphoribosyl-AMP cyclohydrolase [Snodgrassella alvi].	44.83	116	63	1	17	131	8	123	2e-27	109
rs:WP_003537400	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Erysipelotrichaceae].	50.52	97	48	0	20	116	5	101	2e-27	111
rs:WP_019971201	phosphoribosyl-AMP cyclohydrolase [Mycobacterium sp. 141].	53.68	95	44	0	18	112	12	106	2e-27	108
rs:WP_019512073	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mycobacterium].	53.61	97	45	0	16	112	9	105	2e-27	108
rs:WP_000954826	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	47.79	113	49	1	24	126	17	129	2e-27	111
rs:WP_018921924	hypothetical protein [Salsuginibacillus kocurii].	49.50	101	51	0	18	118	6	106	2e-27	111
tr:Q1YNB2_MOBAS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	44.88	127	61	3	3	127	15	134	2e-27	109
rs:WP_018669842	phosphoribosyl-ATP pyrophosphatase [Brevibacillus laterosporus].	50.00	98	49	0	15	112	7	104	2e-27	111
rs:WP_002171064	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacillus].	53.33	90	42	0	24	113	8	97	2e-27	108
rs:WP_025292072	phosphoribosyl-AMP cyclohydrolase [Sphingomonas sanxanigenens].	49.11	112	49	2	15	118	8	119	2e-27	108
rs:WP_008791512	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Coprobacillus].	50.52	97	48	0	20	116	5	101	2e-27	111
rs:WP_016408002	hypothetical protein [Firmicutes bacterium CAG:102].	48.48	99	51	0	18	116	7	105	2e-27	111
rs:WP_000954844	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	47.79	113	49	1	24	126	17	129	2e-27	111
rs:WP_035202754	phosphoribosyl-ATP pyrophosphatase [Bacillus clausii].	48.45	97	50	0	16	112	2	98	2e-27	111
rs:WP_003906639	phosphoribosyl-AMP cyclohydrolase [Mycobacterium tuberculosis].	51.58	95	46	0	18	112	11	105	2e-27	108
rs:WP_024930464	phosphoribosyl-AMP cyclohydrolase [Methylophilus sp. OH31].	50.00	98	48	1	24	120	13	110	2e-27	109
rs:WP_045485094	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. TS-2].	47.37	95	50	0	18	112	6	100	2e-27	111
rs:WP_027411146	phosphoribosyl-ATP pyrophosphatase [Aquimarina muelleri].	50.55	91	45	0	21	111	8	98	2e-27	111
rs:WP_009035812	phosphoribosyl-AMP cyclohydrolase [Indibacter alkaliphilus].	46.67	90	48	0	24	113	13	102	2e-27	111
rs:WP_025360255	phosphoribosyl-AMP cyclohydrolase [Kutzneria albida].	55.79	95	42	0	18	112	11	105	2e-27	108
rs:WP_023825672	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. L103C131B0].	47.01	117	50	2	19	123	25	141	2e-27	109
rs:WP_010488326	phosphoribosyl-AMP cyclohydrolase [Lactobacillus zeae].	51.02	98	47	1	17	113	3	100	2e-27	108
rs:WP_033573034	phosphoribosyl-AMP cyclohydrolase [Lactobacillus rhamnosus].	51.55	97	46	1	18	113	4	100	2e-27	108
rs:WP_010134788	phosphoribosyl-AMP cyclohydrolase [Flavobacteriaceae bacterium S85].	50.00	94	47	0	18	111	3	96	2e-27	110
rs:WP_017907274	phosphoribosyl-AMP cyclohydrolase [Xanthomonas sp. SHU199].	53.93	89	41	0	24	112	23	111	2e-27	111
rs:WP_044992896	hypothetical protein [Lachnospiraceae bacterium P6A3].	50.00	106	53	0	16	121	239	344	2e-27	114
rs:WP_000803974	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	51.61	93	45	0	24	116	8	100	2e-27	108
rs:WP_027136448	phosphoribosyl-ATP pyrophosphatase [Gaetbulibacter saemankumensis].	43.22	118	56	2	17	123	2	119	2e-27	110
rs:WP_040448816	hypothetical protein, partial [Ktedonobacter racemifer].	43.64	110	61	1	17	125	5	114	2e-27	108
rs:WP_033580421	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillus].	50.00	96	48	0	17	112	5	100	2e-27	111
sp:HIS3_SYNFM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	54.64	97	43	1	24	119	12	108	2e-27	108
gpu:CP011489_1221	phosphoribosyl-AMP cyclohydrolase [Actinobacteria bacterium IMCC26256]	47.22	108	56	1	14	120	13	120	2e-27	108
rs:WP_011247885	phosphoribosyl-ATP pyrophosphatase [Bacillus clausii].	48.45	97	50	0	16	112	2	98	2e-27	111
rs:WP_015240669	phosphoribosyl-AMP cyclohydrolase [Bacillus amyloliquefaciens].	46.30	108	58	0	18	125	7	114	2e-27	111
rs:WP_023741482	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. LNJC395A00].	47.01	117	50	2	19	123	25	141	2e-27	109
rs:WP_029714530	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. JGI 001006-L10].	50.00	96	48	0	17	112	5	100	2e-27	111
rs:WP_039253708	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillus].	46.30	108	58	0	18	125	7	114	3e-27	111
rs:WP_015418300	phosphoribosyl-AMP cyclohydrolase [Bacillus amyloliquefaciens].	46.30	108	58	0	18	125	7	114	3e-27	111
rs:WP_027987258	hypothetical protein [delta proteobacterium JGI 0002000-E07].	55.06	89	40	0	24	112	9	97	3e-27	110
rs:WP_025717828	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. 1-18].	51.04	96	47	0	17	112	17	112	3e-27	112
rs:WP_041441185	phosphoribosyl-AMP cyclohydrolase [Syntrophobacter fumaroxidans].	54.64	97	43	1	24	119	10	106	3e-27	108
rs:WP_036441838	phosphoribosyl-AMP cyclohydrolase [Mycobacterium mageritense].	51.92	104	50	0	18	121	11	114	3e-27	108
rs:WP_000954839	histidine biosynthesis bifunctional protein HisIE [Salmonella enterica].	47.79	113	49	1	24	126	17	129	3e-27	111
rs:WP_029353096	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium ciceri].	52.00	100	46	1	19	116	25	124	3e-27	109
rs:WP_005687495	phosphoribosyl-AMP cyclohydrolase [Lactobacillus rhamnosus].	51.55	97	46	1	18	113	4	100	3e-27	108
rs:WP_025285339	phosphoribosyl-ATP pyrophosphatase [Bacillus amyloliquefaciens].	46.30	108	58	0	18	125	7	114	3e-27	111
rs:WP_032876234	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillus subtilis group].	46.30	108	58	0	18	125	7	114	3e-27	111
rs:WP_044397766	phosphoribosyl-ATP pyrophosphatase [Lacinutrix sp. Hel_I_90].	49.50	101	48	1	11	111	1	98	3e-27	110
rs:WP_027068638	phosphoribosyl-ATP pyrophosphatase [Lysobacter defluvii].	55.43	92	41	0	21	112	11	102	3e-27	110
sp:HIS3_BACCQ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.22	90	43	0	24	113	8	97	3e-27	108
rs:WP_023695458	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mesorhizobium].	47.01	117	50	2	19	123	25	141	3e-27	109
rs:WP_000954841	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	46.90	113	50	1	24	126	17	129	3e-27	110
rs:WP_016937818	phosphoribosyl-ATP pyrophosphatase [Bacillus siamensis].	46.30	108	58	0	18	125	7	114	3e-27	111
rs:WP_000803960	phosphoribosyl-AMP cyclohydrolase [Bacillus sp. 7_6_55CFAA_CT2].	53.33	90	42	0	24	113	8	97	3e-27	108
rs:WP_040827317	phosphoribosyl-ATP pyrophosphatase [Thermaerobacter subterraneus].	50.52	97	48	0	17	113	4	100	3e-27	112
sp:HIS3_MYCLB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.63	95	45	0	18	112	11	105	3e-27	108
rs:WP_006797604	phosphoribosyl-AMP cyclohydrolase [Dysgonomonas gadei].	46.08	102	49	1	11	112	3	98	3e-27	110
rs:WP_033372700	phosphoribosyl-AMP cyclohydrolase [Sandarakinorhabdus sp. AAP62].	54.46	101	46	0	19	119	19	119	3e-27	108
rs:WP_032237284	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	51.11	90	44	0	23	112	12	101	3e-27	110
rs:WP_012573480	phosphoribosyl-AMP cyclohydrolase [Candidatus Azobacteroides pseudotrichonymphae].	50.00	90	45	0	23	112	9	98	3e-27	110
rs:WP_046636171	phosphoribosyl-AMP cyclohydrolase [Neorhizobium galegae].	46.15	117	61	1	17	131	22	138	3e-27	109
rs:WP_007242953	phosphoribosyl-AMP cyclohydrolase [Haemophilus pittmaniae].	41.59	113	65	1	13	124	2	114	3e-27	111
rs:WP_026625225	phosphoribosyl-ATP pyrophosphatase [Dysgonomonas capnocytophagoides].	47.06	102	48	1	11	112	3	98	3e-27	110
tr:K0KBW3_SACES	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	54.74	95	43	0	18	112	46	140	3e-27	109
rs:WP_036154234	phosphoribosyl-ATP pyrophosphatase [Maribacter forsetii].	47.52	101	53	0	11	111	3	103	3e-27	110
rs:WP_046188246	phosphoribosyl-AMP cyclohydrolase [Mycobacterium arupense].	53.68	95	44	0	18	112	12	106	3e-27	108
rs:WP_023181973	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	52.81	89	42	0	24	112	17	105	3e-27	110
rs:WP_011393526	phosphoribosyl-AMP cyclohydrolase [Moorella thermoacetica].	51.55	97	47	0	18	114	9	105	3e-27	112
rs:WP_036200372	phosphoribosyl-ATP pyrophosphatase [Lysinibacillus sinduriensis].	42.34	111	64	0	18	128	5	115	3e-27	111
rs:WP_000803985	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacillus cereus group].	52.22	90	43	0	24	113	8	97	3e-27	108
rs:WP_002135179	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	53.33	90	42	0	24	113	8	97	3e-27	108
rs:WP_035455790	phosphoribosyl-AMP cyclohydrolase [Lactobacillus composti].	46.43	112	57	1	7	118	2	110	3e-27	108
rs:WP_004232518	phosphoribosyl-AMP cyclohydrolase [Streptococcus equinus].	53.06	98	45	1	17	113	5	102	3e-27	108
rs:WP_025673433	phosphoribosyl-ATP pyrophosphatase [Salinivibrio socompensis].	52.22	90	43	0	23	112	15	104	3e-27	110
rs:WP_008831862	phosphoribosyl-AMP cyclohydrolase [Sphingomonas sp. LH128].	50.53	95	47	0	19	113	18	112	3e-27	108
rs:WP_041970773	phosphoribosyl-ATP pyrophosphatase, partial [Peptoclostridium difficile].	45.05	111	61	0	17	127	19	129	3e-27	110
tr:K6QCH8_9FIRM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	50.52	97	48	0	17	113	37	133	3e-27	113
rs:WP_023238553	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	47.79	113	49	1	24	126	17	129	3e-27	110
rs:WP_047313922	phosphoribosyl-AMP cyclohydrolase [Mycobacterium haemophilum].	51.58	95	46	0	18	112	11	105	3e-27	108
rs:WP_000954853	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	47.79	113	49	1	24	126	17	129	3e-27	110
rs:WP_023681612	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mesorhizobium].	47.01	117	50	2	19	123	25	141	3e-27	109
rs:WP_023688273	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mesorhizobium].	52.00	100	46	1	19	116	25	124	3e-27	109
rs:WP_007404284	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Sphingomonas].	49.49	99	50	0	19	117	14	112	3e-27	108
rs:WP_034553084	phosphoribosyl-ATP diphosphatase [Helicobacter apodemus].	47.87	94	49	0	24	117	14	107	3e-27	111
rs:WP_045897102	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	50.56	89	44	0	24	112	17	105	3e-27	110
rs:WP_023729882	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mesorhizobium].	52.00	100	46	1	19	116	25	124	3e-27	109
rs:WP_038543083	phosphoribosyl-AMP cyclohydrolase [Neorhizobium galegae].	45.30	117	62	1	17	131	22	138	3e-27	109
rs:WP_000954852	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	47.79	113	49	1	24	126	17	129	3e-27	110
rs:WP_037563538	phosphoribosyl-AMP cyclohydrolase [Spirochaeta sp. JC202].	47.71	109	56	1	23	130	8	116	3e-27	108
rs:WP_022793874	phosphoribosyl-ATP pyrophosphatase [Marinococcus halotolerans].	50.53	95	47	0	18	112	6	100	3e-27	110
rs:WP_043082991	phosphoribosyl-ATP pyrophosphatase [Pluralibacter gergoviae].	52.81	89	42	0	24	112	13	101	3e-27	110
rs:WP_028330969	phosphoribosyl-ATP pyrophosphatase [Brachyspira alvinipulli].	42.15	121	68	1	12	130	3	123	4e-27	111
rs:WP_007313780	phosphoribosyl-AMP cyclohydrolase [Methanolinea tarda].	51.06	94	46	0	24	117	9	102	4e-27	108
rs:WP_025740139	phosphoribosyl-ATP pyrophosphatase [Salinivibrio socompensis].	52.22	90	43	0	23	112	15	104	4e-27	110
rs:WP_037082339	phosphoribosyl-AMP cyclohydrolase [Rhizobium vignae].	46.15	117	61	1	17	131	22	138	4e-27	109
rs:WP_020844655	phosphoribosyl-AMP cyclohydrolase [Salmonella bongori].	47.79	113	49	1	24	126	17	129	4e-27	110
rs:WP_045287832	phosphoribosyl-ATP pyrophosphatase [Pluralibacter gergoviae].	52.81	89	42	0	24	112	13	101	4e-27	110
rs:WP_000803982	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	53.33	90	42	0	24	113	8	97	4e-27	107
rs:WP_012292228	phosphoribosyl-ATP pyrophosphatase [Lysinibacillus sphaericus].	47.00	100	53	0	18	117	5	104	4e-27	110
rs:WP_044057495	phosphoribosyl-ATP pyrophosphatase [Alteromonas australica].	52.22	90	43	0	24	113	18	107	4e-27	110
rs:WP_007407429	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillus].	46.30	108	58	0	18	125	7	114	4e-27	110
tr:U1RS99_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	54.84	93	42	0	28	120	3	95	4e-27	107
rs:WP_046222306	phosphoribosyl-ATP pyrophosphatase [Photobacterium halotolerans].	49.44	89	45	0	24	112	14	102	4e-27	110
rs:WP_018600135	phosphoribosyl-AMP cyclohydrolase [Mycobacterium sp. 155].	53.68	95	44	0	18	112	12	106	4e-27	108
rs:WP_034747927	phosphoribosyl-ATP pyrophosphatase [Bacillus wakoensis].	48.96	96	49	0	17	112	5	100	4e-27	110
rs:WP_022040195	phosphoribosyl-ATP pyrophosphatase [Bacteroides sp. CAG:702].	51.69	89	43	0	24	112	10	98	4e-27	110
rs:WP_036795456	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Photobacterium].	51.11	90	44	0	23	112	13	102	4e-27	110
rs:WP_012118542	phosphoribosyl-ATP pyrophosphatase [Bacillus amyloliquefaciens].	46.30	108	58	0	18	125	7	114	4e-27	110
rs:WP_044893534	phosphoribosyl-ATP pyrophosphatase [Bacillus alveayuensis].	51.04	96	47	0	18	113	6	101	4e-27	110
rs:WP_024249718	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Enterobacteriaceae].	51.11	90	44	0	23	112	12	101	4e-27	110
rs:WP_044793714	phosphoribosyl-AMP cyclohydrolase [Bacillus thuringiensis].	51.11	90	44	0	24	113	8	97	4e-27	107
rs:WP_016133974	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	53.33	90	42	0	24	113	8	97	4e-27	107
rs:WP_027834268	phosphoribosyl-AMP cyclohydrolase [Maritalea myrionectae].	50.00	100	48	1	19	116	24	123	4e-27	109
rs:WP_023707145	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mesorhizobium].	47.01	117	50	2	19	123	25	141	4e-27	109
rs:WP_034212428	phosphoribosyl-ATP pyrophosphatase [Arenimonas metalli].	53.26	92	43	0	21	112	13	104	4e-27	110
rs:WP_032547346	phosphoribosyl-ATP pyrophosphatase [Peptoclostridium difficile].	45.05	111	61	0	17	127	3	113	4e-27	110
rs:WP_044173188	phosphoribosyl-ATP pyrophosphatase [Enterobacter massiliensis].	51.69	89	43	0	24	112	17	105	4e-27	110
rs:WP_027253469	phosphoribosyl-ATP pyrophosphatase [Photobacterium halotolerans].	49.44	89	45	0	24	112	14	102	4e-27	110
tr:G6EJ64_9SPHN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	48.60	107	54	1	19	124	49	155	4e-27	109
rs:WP_033706582	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	53.33	90	42	0	24	113	8	97	4e-27	107
rs:WP_045180384	phosphoribosyl-ATP pyrophosphatase [Elizabethkingia sp. BM10].	48.91	92	47	0	21	112	8	99	4e-27	110
rs:WP_040326456	phosphoribosyl-AMP cyclohydrolase, partial [Aurantimonas manganoxydans].	45.69	116	56	2	3	116	15	125	4e-27	108
rs:WP_040963731	phosphoribosyl-AMP cyclohydrolase [Erythrobacter vulgaris].	46.53	101	54	0	19	119	17	117	4e-27	108
rs:WP_034869222	phosphoribosyl-ATP pyrophosphatase [Elizabethkingia miricola].	48.91	92	47	0	21	112	8	99	4e-27	110
rs:WP_028735317	phosphoribosyl-AMP cyclohydrolase [Rhizobium selenitireducens].	52.94	102	46	1	17	116	22	123	4e-27	109
rs:WP_046094607	phosphoribosyl-ATP pyrophosphatase [Salmonella enterica].	46.90	113	50	1	24	126	17	129	4e-27	110
rs:WP_007696146	phosphoribosyl-AMP cyclohydrolase [Rhizobium sp. AP16].	47.97	123	59	2	10	130	18	137	4e-27	108
rs:WP_042679955	phosphoribosyl-ATP pyrophosphatase [Thermococcus sp. ES1].	53.33	90	41	1	24	113	17	105	4e-27	110
rs:WP_032279903	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	51.11	90	44	0	23	112	12	101	4e-27	110
rs:WP_005370765	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Methylomicrobium].	48.45	97	49	1	18	113	9	105	4e-27	108
rs:WP_005214564	phosphoribosyl-AMP cyclohydrolase [Clostridium celatum].	51.06	94	46	0	24	117	16	109	4e-27	107
sp:HIS3_MYCVP	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.58	97	46	0	16	112	10	106	4e-27	108
rs:WP_021375215	phosphoribosyl-ATP diphosphatase [Peptoclostridium difficile].	45.05	111	61	0	17	127	19	129	4e-27	110
tr:W0I679_9EURY	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	53.33	90	41	1	24	113	15	103	4e-27	110
rs:WP_007461803	phosphoribosyl-AMP cyclohydrolase [Photobacterium sp. AK15].	51.69	89	43	0	24	112	14	102	4e-27	110
tr:D8K1F7_DEHLB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	50.00	96	48	0	18	113	8	103	4e-27	108
rs:WP_035727674	phosphoribosyl-ATP pyrophosphatase [Flexibacter elegans].	50.00	102	46	1	11	112	1	97	5e-27	110
rs:WP_038810644	phosphoribosyl-ATP pyrophosphatase [Peptoclostridium difficile].	45.05	111	61	0	17	127	3	113	5e-27	110
rs:WP_013727537	phosphoribosyl-AMP cyclohydrolase [Lactobacillus buchneri].	52.22	90	43	0	24	113	11	100	5e-27	107
rs:WP_000803968	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	51.11	90	44	0	24	113	8	97	5e-27	107
rs:WP_027441971	phosphoribosyl-AMP cyclohydrolase [Porphyrobacter cryptus].	46.73	107	57	0	19	125	20	126	5e-27	108
rs:WP_024446338	phosphoribosyl-AMP cyclohydrolase [Mycobacterium iranicum].	52.58	97	46	0	16	112	9	105	5e-27	108
rs:WP_000954851	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	47.79	113	49	1	24	126	17	129	5e-27	110
rs:WP_008996803	phosphoribosyl-AMP cyclohydrolase [Novosphingobium sp. Rr 2-17].	49.47	95	48	0	19	113	18	112	5e-27	108
rs:WP_045512267	phosphoribosyl-ATP pyrophosphatase [Bacillus amyloliquefaciens].	46.30	108	58	0	18	125	7	114	5e-27	110
rs:WP_022326882	histidine biosynthesis protein HisIE [Prevotella sp. CAG:732].	52.22	90	43	0	23	112	9	98	5e-27	110
rs:WP_015480184	phosphoribosyl-AMP cyclohydrolase [Polaribacter sp. MED152].	48.45	97	48	1	17	111	2	98	5e-27	110
rs:WP_026700693	phosphoribosyl-ATP pyrophosphatase [Bacillus aidingensis].	48.48	99	51	0	14	112	2	100	5e-27	110
rs:WP_032512004	phosphoribosyl-ATP pyrophosphatase [Peptoclostridium difficile].	45.05	111	61	0	17	127	3	113	5e-27	110
rs:WP_002201197	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	53.33	90	42	0	24	113	8	97	5e-27	107
sp:HIS3_BACC1	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	51.11	90	44	0	24	113	8	97	5e-27	107
rs:WP_045843022	phosphoribosyl-AMP cyclohydrolase [Mycobacterium lepromatosis].	52.63	95	45	0	18	112	11	105	5e-27	107
rs:WP_021360531	phosphoribosyl-ATP diphosphatase [Peptoclostridium difficile].	45.05	111	61	0	17	127	19	129	5e-27	110
rs:WP_028541874	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. UNCCL52].	49.48	97	49	0	17	113	17	113	5e-27	111
rs:WP_025721803	phosphoribosyl-ATP pyrophosphatase [Paenibacillus polymyxa].	49.48	97	49	0	17	113	17	113	5e-27	111
rs:WP_006842635	phosphoribosyl-AMP cyclohydrolase [Dysgonomonas mossii].	45.13	113	53	2	11	123	3	106	5e-27	110
rs:WP_036790558	phosphoribosyl-AMP cyclohydrolase [Pleomorphomonas koreensis].	52.38	105	48	1	17	119	23	127	5e-27	108
rs:WP_010517047	phosphoribosyl-AMP cyclohydrolase [Mesoflavibacter zeaxanthinifaciens].	51.14	88	43	0	24	111	11	98	5e-27	110
rs:WP_005831422	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacteroides].	50.00	102	45	2	11	112	1	96	5e-27	110
rs:WP_009038209	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacteroides].	50.00	102	45	2	11	112	1	96	5e-27	110
rs:WP_003834201	phosphoribosyl-AMP cyclohydrolase [Citrobacter freundii].	46.90	113	50	1	24	126	17	129	5e-27	110
rs:WP_008990693	phosphoribosyl-AMP cyclohydrolase [Galbibacter marinus].	47.52	101	48	1	11	111	9	104	5e-27	110
rs:WP_015638838	phosphoribosyl-AMP cyclohydrolase [Lactobacillus fermentum].	53.19	94	44	0	24	117	8	101	5e-27	107
sp:HIS3_LACCB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	48.11	106	54	1	17	121	3	108	5e-27	107
rs:WP_009886553	phosphoribosyl-ATP pyrophosphatase [Ferroplasma acidarmanus].	48.51	101	47	2	12	112	3	98	5e-27	110
rs:WP_032509837	phosphoribosyl-ATP pyrophosphatase [Peptoclostridium difficile].	45.05	111	61	0	17	127	3	113	5e-27	110
rs:WP_004346783	phosphoribosyl-AMP cyclohydrolase [Prevotella buccae].	50.00	102	45	1	11	112	3	98	5e-27	110
rs:WP_005430174	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Sutterella].	48.54	103	52	1	14	115	6	108	5e-27	110
rs:WP_038560656	imidazole glycerol phosphate synthase [Terribacillus aidingensis].	49.45	91	46	0	24	114	8	98	5e-27	110
rs:WP_022586213	phosphoribosyl-ATP pyrophosphatase [Brevibacillus laterosporus].	50.98	102	50	0	18	119	10	111	5e-27	110
rs:WP_016198201	phosphoribosyl-ATP pyrophosphohydrolase [Elizabethkingia meningoseptica].	50.00	92	46	0	21	112	8	99	5e-27	110
rs:WP_034854730	phosphoribosyl-AMP cyclohydrolase [Ensifer sojae].	47.01	117	58	2	17	129	22	138	5e-27	108
rs:WP_003429791	phosphoribosyl-ATP pyrophosphatase [Peptoclostridium difficile].	45.05	111	61	0	17	127	19	129	5e-27	110
rs:WP_023186601	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	46.90	113	50	1	24	126	17	129	5e-27	110
rs:WP_023983070	phosphoribosyl-ATP diphosphatase [Prevotella oralis].	52.22	90	43	0	23	112	9	98	5e-27	110
rs:WP_029703307	phosphoribosyl-AMP cyclohydrolase [Aurantimonas coralicida].	48.21	112	54	2	19	128	30	139	5e-27	108
rs:WP_016274336	histidine biosynthesis HisIE [Bacteroides uniformis].	50.00	102	45	2	11	112	1	96	5e-27	110
rs:WP_015447343	phosphoribosyl-AMP cyclohydrolase [Rhodanobacter denitrificans].	50.48	105	51	1	9	112	2	106	5e-27	110
rs:WP_013308249	phosphoribosyl-ATP pyrophosphatase [Paenibacillus polymyxa].	49.48	97	49	0	17	113	17	113	5e-27	111
rs:WP_000803981	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	52.22	90	43	0	24	113	8	97	5e-27	107
rs:WP_003436669	phosphoribosyl-ATP pyrophosphatase [Peptoclostridium difficile].	45.05	111	61	0	17	127	19	129	5e-27	110
rs:WP_013553547	phosphoribosyl-ATP pyrophosphatase [Nitratifractor salsuginis].	57.89	95	40	0	25	119	10	104	5e-27	110
rs:WP_004342313	phosphoribosyl-AMP cyclohydrolase [Prevotella buccae].	50.00	102	45	1	11	112	3	98	6e-27	110
rs:WP_002644991	phosphoribosyl-AMP cyclohydrolase [Planctomyces maris].	52.38	105	48	1	19	121	25	129	6e-27	108
rs:WP_012882372	phosphoribosyl-AMP cyclohydrolase [Dehalococcoides mccartyi].	50.00	100	50	0	18	117	3	102	6e-27	107
rs:WP_011309687	phosphoribosyl-AMP cyclohydrolase [Dehalococcoides mccartyi].	50.00	100	50	0	18	117	3	102	6e-27	107
rs:WP_047245380	phosphoribosyl-ATP pyrophosphatase [Maribacter thermophilus].	46.53	101	54	0	11	111	1	101	6e-27	110
rs:WP_002953885	phosphoribosyl-ATP pyrophosphatase [Salmonella enterica].	46.90	113	50	1	24	126	17	129	6e-27	110
rs:WP_039044439	phosphoribosyl-ATP pyrophosphatase [Sporosarcina sp. ZBG7A].	48.96	96	49	0	17	112	5	100	6e-27	110
rs:WP_011861249	phosphoribosyl-ATP pyrophosphatase [Peptoclostridium difficile].	45.05	111	61	0	17	127	19	129	6e-27	110
rs:WP_044701940	phosphoribosyl-ATP pyrophosphatase [Citrobacter freundii].	46.90	113	50	1	24	126	17	129	6e-27	110
rs:WP_023226685	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	47.79	113	49	1	24	126	17	129	6e-27	110
rs:WP_039008736	phosphoribosyl-ATP pyrophosphatase [Xanthomonas translucens].	49.50	101	50	1	13	112	10	110	6e-27	110
rs:WP_028908522	phosphoribosyl-ATP pyrophosphatase [Prevotella ruminicola].	45.61	114	56	1	11	124	3	110	6e-27	110
rs:WP_013231389	phosphoribosyl-AMP cyclohydrolase [Leuconostoc gelidum].	45.45	110	57	1	17	123	6	115	6e-27	107
rs:WP_015482464	phosphoribosyl-AMP cyclohydrolase [Candidatus Portiera aleyrodidarum].	50.00	98	49	0	17	114	27	124	6e-27	108
rs:WP_021840126	phosphoribosyl-AMP cyclohydrolase [Veillonella sp. CAG:933].	50.00	94	47	0	24	117	31	124	6e-27	108
rs:WP_032510658	phosphoribosyl-ATP pyrophosphatase [Peptoclostridium difficile].	45.05	111	61	0	17	127	12	122	6e-27	110
rs:WP_032510217	phosphoribosyl-ATP pyrophosphatase [Peptoclostridium difficile].	45.05	111	61	0	17	127	12	122	6e-27	110
rs:WP_002503500	phosphoribosyl-AMP cyclohydrolase [Staphylococcus epidermidis].	48.94	94	48	0	24	117	10	103	6e-27	110
rs:WP_041893129	phosphoribosyl-ATP pyrophosphatase [Myroides profundi].	45.00	120	56	2	18	127	5	124	6e-27	110
rs:WP_042487857	phosphoribosyl-AMP cyclohydrolase [Sphingomonas parapaucimobilis].	51.52	99	48	0	19	117	14	112	6e-27	107
rs:WP_010098217	phosphoribosyl-ATP pyrophosphatase [Ornithinibacillus scapharcae].	48.54	103	52	1	17	118	7	109	6e-27	110
rs:WP_029016388	phosphoribosyl-AMP cyclohydrolase [alpha proteobacterium SCGC AAA028-D10].	49.52	105	52	1	19	122	20	124	6e-27	108
rs:WP_016648973	phosphoribosyl-ATP diphosphatase [Myroides odoratimimus].	45.00	120	56	2	18	127	5	124	6e-27	110
rs:WP_000954840	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	46.90	113	50	1	24	126	17	129	6e-27	110
rs:WP_026660163	hypothetical protein [Butyrivibrio sp. AC2005].	48.04	102	53	0	12	113	221	322	6e-27	113
rs:WP_040249050	phosphoribosyl-ATP pyrophosphatase [Psychroserpens mesophilus].	50.00	96	47	1	17	111	2	97	6e-27	110
rs:WP_023678881	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. LSJC280B00].	47.50	120	48	3	19	123	25	144	6e-27	108
rs:WP_005832371	phosphoribosyl-AMP cyclohydrolase [Bacteroides uniformis].	50.00	102	45	2	11	112	1	96	6e-27	110
rs:WP_003681876	phosphoribosyl-AMP cyclohydrolase [Lactobacillus fermentum].	53.19	94	44	0	24	117	8	101	6e-27	107
rs:WP_046312754	phosphoribosyl-ATP pyrophosphatase [Pontibacter korlensis].	47.06	102	48	1	11	112	3	98	6e-27	110
rs:WP_024280125	phosphoribosyl-AMP cyclohydrolase [Xanthobacter sp. 126].	49.09	110	53	2	19	125	30	139	6e-27	108
rs:WP_038174497	phosphoribosyl-ATP pyrophosphatase [Vibrio pacinii].	52.81	89	42	0	24	112	22	110	6e-27	110
rs:WP_021349426	phosphoribosyl-AMP cyclohydrolase [Lactobacillus fermentum].	53.19	94	44	0	24	117	8	101	6e-27	107
sp:HIS3_BACC7	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	52.22	90	43	0	24	113	8	97	6e-27	107
rs:WP_042848154	phosphoribosyl-ATP pyrophosphatase, partial [Salmonella enterica].	46.90	113	50	1	24	126	17	129	6e-27	110
rs:WP_003030122	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Citrobacter].	46.90	113	50	1	24	126	17	129	6e-27	110
rs:WP_016153559	histidine biosynthesis HisIE [Citrobacter sp. KTE151].	46.90	113	50	1	24	126	17	129	6e-27	110
rs:WP_000803972	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	51.11	90	44	0	24	113	8	97	7e-27	107
rs:WP_000956425	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Enterobacteriaceae].	46.90	113	50	1	24	126	17	129	7e-27	110
rs:WP_000956426	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	46.90	113	50	1	24	126	17	129	7e-27	110
rs:WP_009463628	phosphoribosyl-AMP cyclohydrolase [Ahrensia sp. R2A130].	45.61	114	60	1	19	130	15	128	7e-27	108
sp:HIS3_LACC3	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	48.11	106	54	1	17	121	3	108	7e-27	107
rs:WP_003420108	phosphoribosyl-ATP pyrophosphatase [Peptoclostridium difficile].	45.05	111	61	0	17	127	19	129	7e-27	110
tr:X0PH57_9LACO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	53.26	92	43	0	25	116	1	92	7e-27	107
rs:WP_036400870	phosphoribosyl-AMP cyclohydrolase [Mycobacterium kansasii].	53.68	95	44	0	18	112	11	105	7e-27	107
rs:WP_014822772	phosphoribosyl-ATP pyrophosphatase [Solibacillus silvestris].	47.57	103	53	1	17	118	2	104	7e-27	110
rs:WP_035134344	phosphoribosyl-ATP pyrophosphatase [Flavobacterium beibuense].	46.15	117	53	2	20	126	5	121	7e-27	109
rs:WP_010857381	phosphoribosyl-AMP cyclohydrolase [Lysinibacillus sphaericus].	43.81	105	59	0	17	121	4	108	7e-27	110
rs:WP_023576747	phosphoribosyl-AMP cyclohydrolase [Flavobacterium saliperosum].	50.55	91	45	0	21	111	8	98	7e-27	109
rs:WP_038395444	phosphoribosyl-ATP pyrophosphatase [Salmonella enterica].	46.02	113	51	1	24	126	17	129	7e-27	110
rs:WP_033153004	phosphoribosyl-AMP cyclohydrolase [Streptococcus equinus].	53.19	94	44	0	21	114	10	103	7e-27	107
rs:WP_013947724	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Hyphomicrobium].	46.43	112	56	2	19	126	14	125	7e-27	108
rs:WP_027457741	phosphoribosyl-AMP cyclohydrolase [Dechloromonas agitata].	46.85	111	56	3	17	126	13	121	7e-27	107
rs:WP_040304032	hypothetical protein, partial [Campylobacter gracilis].	54.35	92	41	1	23	113	9	100	7e-27	107
rs:WP_014815786	phosphoribosyl-AMP cyclohydrolase [Mycobacterium chubuense].	50.48	105	49	1	11	112	1	105	7e-27	107
rs:WP_022467810	hypothetical protein [Acidaminococcus sp. CAG:917].	41.38	116	66	1	18	131	7	122	7e-27	110
rs:WP_021363480	phosphoribosyl-ATP diphosphatase [Peptoclostridium difficile].	45.05	111	61	0	17	127	19	129	7e-27	110
rs:WP_008587107	phosphoribosyl-ATP pyrophosphatase [Salimicrobium sp. MJ3].	48.98	98	50	0	15	112	3	100	8e-27	109
rs:WP_006354323	phosphoribosyl-ATP pyrophosphatase [[Clostridium] methylpentosum].	47.62	105	55	0	18	122	7	111	8e-27	110
rs:WP_038968626	phosphoribosyl-ATP pyrophosphatase [Vibrio vulnificus].	52.81	89	42	0	24	112	22	110	8e-27	110
rs:WP_043990120	phosphoribosyl-ATP pyrophosphatase, partial [Vibrio cholerae].	52.81	89	42	0	24	112	21	109	8e-27	109
rs:WP_034626791	phosphoribosyl-ATP pyrophosphatase [Bacillus okhensis].	47.17	106	55	1	18	122	6	111	8e-27	110
rs:WP_009085270	phosphoribosyl-AMP cyclohydrolase [Elizabethkingia anophelis].	48.91	92	47	0	21	112	8	99	8e-27	109
rs:WP_004186437	phosphoribosyl-AMP cyclohydrolase [Streptococcus sanguinis].	51.02	98	48	0	21	118	10	107	8e-27	107
rs:WP_006584188	phosphoribosyl-ATP pyrophosphatase [Thermanaerovibrio velox].	46.23	106	57	0	11	116	1	106	8e-27	110
rs:WP_001067505	phosphoribosyl-AMP cyclohydrolase [Vibrio mimicus].	48.04	102	53	0	24	125	21	122	8e-27	110
tr:A6ESM3_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	47.37	95	50	0	18	112	3	97	8e-27	109
rs:WP_000803976	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	51.11	90	44	0	24	113	8	97	8e-27	107
rs:WP_032659329	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	50.56	89	44	0	24	112	17	105	8e-27	109
rs:WP_038586986	phosphoribosyl-AMP cyclohydrolase [Neorhizobium galegae].	45.30	117	62	1	17	131	22	138	8e-27	108
rs:WP_024534017	phosphoribosyl-ATP pyrophosphatase [Sporosarcina sp. EUR3 2.2.2].	49.48	97	49	0	17	113	8	104	8e-27	110
rs:WP_033346066	phosphoribosyl-AMP cyclohydrolase [Catenuloplanes japonicus].	52.81	89	42	0	24	112	27	115	8e-27	107
rs:WP_039274194	phosphoribosyl-ATP pyrophosphatase [Paenibacillus polymyxa].	49.48	97	49	0	17	113	17	113	8e-27	110
rs:WP_006646954	phosphoribosyl-AMP cyclohydrolase [Photobacterium sp. SKA34].	45.79	107	57	1	23	129	13	118	8e-27	109
rs:WP_008626731	phosphoribosyl-AMP cyclohydrolase [Mariniradius saccharolyticus].	49.44	89	45	0	24	112	13	101	8e-27	109
rs:WP_045324837	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	50.56	89	44	0	24	112	17	105	8e-27	109
rs:WP_005698449	phosphoribosyl-AMP cyclohydrolase [Haemophilus parainfluenzae].	41.59	113	65	1	13	124	2	114	8e-27	110
rs:WP_029278670	phosphoribosyl-ATP pyrophosphatase [Pedobacter borealis].	47.62	105	54	1	11	114	1	105	8e-27	109
rs:WP_000803973	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	52.22	90	43	0	24	113	8	97	8e-27	107
rs:WP_016150591	histidine biosynthesis HisIE [Citrobacter sp. KTE30].	46.02	113	51	1	24	126	17	129	8e-27	109
rs:WP_034764256	phosphoribosyl-ATP pyrophosphatase [Bacillus vietnamensis].	47.52	101	53	0	16	116	8	108	8e-27	109
rs:WP_031613629	hypothetical protein, partial [Salmonella enterica].	46.90	113	50	1	24	126	17	129	9e-27	108
rs:WP_045337605	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	50.56	89	44	0	24	112	17	105	9e-27	109
rs:WP_035318965	phosphoribosyl-ATP pyrophosphatase [Brevibacillus laterosporus].	52.63	95	45	0	18	112	10	104	9e-27	110
rs:WP_026669813	hypothetical protein [Butyrivibrio sp. AE3006].	51.04	96	47	0	18	113	227	322	9e-27	112
sp:HIS2_VIBCH	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	52.81	89	42	0	24	112	21	109	9e-27	109
rs:WP_029906090	phosphoribosyl-ATP pyrophosphatase [Prevotella sp. 10(H)].	48.89	90	46	0	23	112	9	98	9e-27	109
rs:WP_026791355	phosphoribosyl-AMP cyclohydrolase [Pleomorphomonas oryzae].	50.93	108	51	1	14	119	21	128	9e-27	108
rs:WP_026836354	phosphoribosyl-AMP cyclohydrolase [Geovibrio sp. L21-Ace-BES].	52.08	96	46	0	24	119	13	108	9e-27	107
rs:WP_034953997	phosphoribosyl-AMP cyclohydrolase [Erythrobacter sp. JL475].	50.53	95	47	0	19	113	21	115	9e-27	107
rs:WP_003859480	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Enterobacter cloacae complex].	50.56	89	44	0	24	112	17	105	9e-27	109
rs:WP_000803983	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	51.11	90	44	0	24	113	8	97	9e-27	107
tr:Q2G6H7_NOVAD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	50.53	95	47	0	19	113	3	97	9e-27	107
rs:WP_006258513	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Myroides].	42.98	114	64	1	18	130	5	118	9e-27	109
tr:B3T307_9ARCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	42.86	105	59	1	11	114	1	105	9e-27	107
rs:WP_018110073	hypothetical protein [Bacteroides propionicifaciens].	48.15	108	54	1	7	112	247	354	9e-27	112
rs:WP_017971722	phosphoribosyl-AMP cyclohydrolase [alpha proteobacterium SCGC AAA280-B11].	49.52	105	52	1	19	122	20	124	9e-27	108
rs:WP_032609641	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae complex].	50.56	89	44	0	24	112	17	105	9e-27	109
rs:WP_046870123	phosphoribosyl-ATP pyrophosphatase [Vibrio cholerae].	52.81	89	42	0	24	112	21	109	9e-27	109
rs:WP_023757565	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. LNHC252B00].	46.15	117	51	2	19	123	25	141	9e-27	108
rs:WP_035796747	hypothetical protein [Butyrivibrio sp. MB2005].	51.04	96	47	0	18	113	227	322	9e-27	112
rs:WP_003685131	phosphoribosyl-AMP cyclohydrolase [Lactobacillus fermentum].	53.19	94	44	0	24	117	8	101	9e-27	107
rs:WP_039058572	phosphoribosyl-ATP pyrophosphatase [Enterobacter sp. Bisph1].	51.69	89	43	0	24	112	17	105	9e-27	109
rs:WP_001897980	phosphoribosyl-AMP cyclohydrolase [Vibrio cholerae].	52.81	89	42	0	24	112	21	109	9e-27	109
rs:WP_044485330	phosphoribosyl-AMP cyclohydrolase [Mycobacterium tuberculosis].	51.43	105	51	0	18	122	11	115	9e-27	107
rs:WP_010855142	phosphoribosyl-AMP cyclohydrolase [Cyclobacteriaceae bacterium AK24].	51.69	89	43	0	24	112	13	101	9e-27	109
rs:WP_022252400	histidine biosynthesis protein HisIE [Prevotella sp. CAG:386].	52.22	90	43	0	23	112	9	98	9e-27	110
rs:WP_001067501	histidine biosynthesis bifunctional protein HisIE [Vibrio sp. RC586].	52.81	89	42	0	24	112	21	109	9e-27	109
rs:WP_001575888	histidine biosynthesis HisIE [Escherichia coli].	52.81	89	42	0	24	112	13	101	9e-27	109
rs:WP_017969498	phosphoribosyl-AMP cyclohydrolase [alpha proteobacterium SCGC AAA280-P20].	52.00	100	47	1	19	117	20	119	9e-27	108
rs:WP_003575073	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Lactobacillus casei group].	48.98	98	50	0	24	121	11	108	9e-27	107
rs:WP_001067504	phosphoribosyl-AMP cyclohydrolase [Vibrio mimicus].	52.81	89	42	0	24	112	21	109	9e-27	109
rs:WP_001083366	phosphoribosyl-AMP cyclohydrolase [Vibrio cholerae].	52.81	89	42	0	24	112	21	109	9e-27	109
rs:WP_037411097	phosphoribosyl-ATP diphosphatase, partial [Solirubrobacter sp. URHD0082].	50.52	97	48	0	18	114	1	97	9e-27	109
rs:WP_025124762	phosphoribosyl-ATP pyrophosphatase [Myroides odoratimimus].	44.17	120	57	2	18	127	5	124	9e-27	109
rs:WP_005524412	phosphoribosyl-AMP cyclohydrolase [Vibrio mimicus].	52.81	89	42	0	24	112	21	109	9e-27	109
rs:WP_039283247	phosphoribosyl-AMP cyclohydrolase [Novosphingobium malaysiense].	50.53	95	47	0	19	113	18	112	9e-27	107
rs:WP_042415051	phosphoribosyl-ATP pyrophosphatase [Geomicrobium sp. JCM 19038].	50.00	96	48	0	17	112	5	100	9e-27	109
tr:A9ML10_SALAR	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	46.02	113	51	1	24	126	17	129	1e-26	109
rs:WP_013172044	phosphoribosyl-ATP pyrophosphatase [[Bacillus] selenitireducens].	50.53	95	47	0	18	112	4	98	1e-26	109
rs:WP_001067499	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Vibrio].	52.81	89	42	0	24	112	21	109	1e-26	109
rs:WP_037477527	phosphoribosyl-AMP cyclohydrolase [Sphingobium sp. ba1].	48.04	102	53	0	15	116	10	111	1e-26	107
rs:WP_023805328	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium sp. L2C089B000].	46.15	117	51	2	19	123	25	141	1e-26	108
rs:WP_021847561	phosphoribosyl-ATP diphosphatase [Bacteroides sp. CAG:598].	46.60	103	49	1	10	112	4	100	1e-26	109
rs:WP_029167517	phosphoribosyl-AMP cyclohydrolase [alpha proteobacterium SCGC AAA028-C07].	49.52	105	52	1	19	122	20	124	1e-26	108
rs:WP_022577820	phosphoribosyl-AMP cyclohydrolase [Vibrio mimicus].	52.81	89	42	0	24	112	21	109	1e-26	109
rs:WP_009603759	phosphoribosyl-AMP cyclohydrolase [Xanthomonas translucens].	49.50	101	50	1	13	112	21	121	1e-26	109
rs:WP_017970263	phosphoribosyl-AMP cyclohydrolase [alpha proteobacterium SCGC AAA027-J10].	49.52	105	52	1	19	122	20	124	1e-26	108
rs:WP_039709972	hypothetical protein [Scytonema millei].	48.51	101	51	1	13	112	2	102	1e-26	109
rs:WP_041459887	phosphoribosyl-ATP pyrophosphatase [Anaerobaculum mobile].	47.17	106	56	0	16	121	2	107	1e-26	109
rs:WP_008723361	phosphoribosyl-AMP cyclohydrolase [Brachyspira hampsonii].	47.47	99	52	0	18	116	12	110	1e-26	110
rs:WP_046874779	phosphoribosyl-ATP pyrophosphatase [Vibrio alginolyticus].	52.81	89	42	0	24	112	22	110	1e-26	109
rs:WP_000186277	histidine biosynthesis bifunctional protein HisIE [Staphylococcus aureus].	49.46	93	47	0	24	116	11	103	1e-26	109
rs:WP_002147843	phosphoribosyl-AMP cyclohydrolase [Vibrio cholerae].	52.81	89	42	0	24	112	21	109	1e-26	109
rs:WP_046670018	phosphoribosyl-ATP pyrophosphatase [Citrobacter freundii].	46.02	113	51	1	24	126	17	129	1e-26	109
rs:WP_040003357	phosphoribosyl-ATP pyrophosphatase [Flavobacteria bacterium BBFL7].	49.45	91	46	0	22	112	9	99	1e-26	109
rs:WP_046197235	phosphoribosyl-AMP cyclohydrolase [Bacillus sp. UMTAT18].	51.11	90	44	0	24	113	8	97	1e-26	106
sp:HIS3_MYCGI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	53.68	95	44	0	18	112	11	105	1e-26	107
rs:WP_040491812	phosphoribosyl-ATP pyrophosphatase [Formosa sp. AK20].	47.52	101	48	2	11	111	3	98	1e-26	109
rs:WP_013688966	phosphoribosyl-AMP cyclohydrolase [Burkholderia gladioli].	49.09	110	54	1	14	121	28	137	1e-26	108
rs:WP_041220481	phosphoribosyl-AMP cyclohydrolase [Dehalogenimonas lykanthroporepellens].	48.96	96	49	0	18	113	1	96	1e-26	107
rs:WP_000803984	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	51.11	90	44	0	24	113	8	97	1e-26	106
tr:A0A0A6WQG8_CITBR	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	46.90	113	50	1	24	126	17	129	1e-26	109
rs:WP_003932104	phosphoribosyl-AMP cyclohydrolase [Mycobacterium vaccae].	52.63	95	45	0	18	112	12	106	1e-26	107
rs:WP_004395074	phosphoribosyl-AMP cyclohydrolase [Vibrio metschnikovii].	55.06	89	40	0	24	112	22	110	1e-26	109
rs:WP_013368803	phosphoribosyl-ATP pyrophosphatase [Paenibacillus polymyxa].	50.00	96	48	0	17	112	17	112	1e-26	110
rs:WP_032442119	phosphoribosyl-ATP pyrophosphatase [Klebsiella pneumoniae].	52.81	89	42	0	24	112	13	101	1e-26	109
rs:WP_047114538	phosphoribosyl-ATP pyrophosphatase [Brachyspira hyodysenteriae].	44.66	103	57	0	14	116	8	110	1e-26	109
rs:WP_010579788	phosphoribosyl-AMP cyclohydrolase [Lactobacillus vini].	48.39	93	48	0	24	116	9	101	1e-26	106
rs:WP_003838954	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Enterobacteriaceae].	46.02	113	51	1	24	126	17	129	1e-26	109
tr:F0EXP9_9NEIS	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	42.59	108	61	1	11	117	1	108	1e-26	109
rs:WP_000170490	phosphoribosyl-AMP cyclohydrolase [Staphylococcus aureus].	49.46	93	47	0	24	116	11	103	1e-26	109
rs:WP_034937733	phosphoribosyl-ATP pyrophosphatase [Erwinia mallotivora].	49.47	95	48	0	24	118	17	111	1e-26	109
tr:Q26BG3_FLABB	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	49.45	91	46	0	22	112	20	110	1e-26	109
rs:WP_008727126	phosphoribosyl-AMP cyclohydrolase [Brachyspira hampsonii].	46.39	97	52	0	18	114	11	107	1e-26	110
rs:WP_028524315	phosphoribosyl-ATP pyrophosphatase [Runella limosa].	48.89	90	46	0	24	113	13	102	1e-26	109
rs:WP_032099319	phosphoribosyl-ATP pyrophosphatase [Staphylococcus aureus].	49.46	93	47	0	24	116	11	103	1e-26	109
rs:WP_000186283	histidine biosynthesis bifunctional protein HisIE [Staphylococcus aureus].	49.46	93	47	0	24	116	11	103	1e-26	109
sp:HIS2_STAAC	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	49.46	93	47	0	24	116	11	103	1e-26	109
rs:WP_023710659	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mesorhizobium].	51.00	100	47	1	19	116	25	124	1e-26	107
rs:WP_031413022	phosphoribosyl-ATP pyrophosphatase [Brevibacillus laterosporus].	52.63	95	45	0	18	112	10	104	1e-26	109
rs:WP_042692038	phosphoribosyl-AMP cyclohydrolase [Methanobrevibacter oralis].	50.54	93	46	0	21	113	10	102	1e-26	107
rs:WP_013616982	phosphoribosyl-AMP cyclohydrolase [Bacteroides salanitronis].	50.56	89	44	0	24	112	10	98	1e-26	109
rs:WP_033151188	phosphoribosyl-ATP pyrophosphatase [Prevotella sp. RM4].	44.74	114	57	1	11	124	3	110	1e-26	109
rs:WP_002510005	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Staphylococcus].	48.39	93	48	0	24	116	10	102	1e-26	109
rs:WP_018298846	hypothetical protein [Fangia hongkongensis].	47.19	89	47	0	24	112	16	104	1e-26	109
rs:WP_028667184	phosphoribosyl-ATP pyrophosphatase [Runella zeae].	47.78	90	47	0	24	113	14	103	1e-26	109
rs:WP_026688341	phosphoribosyl-ATP pyrophosphatase [Bacillus aurantiacus].	50.53	95	47	0	18	112	6	100	1e-26	109
rs:WP_033858326	phosphoribosyl-ATP pyrophosphatase [Staphylococcus aureus].	49.46	93	47	0	24	116	11	103	1e-26	109
rs:WP_014126692	phosphoribosyl-AMP cyclohydrolase [Thermoproteus tenax].	49.55	111	53	1	24	131	26	136	1e-26	107
rs:WP_041550292	phosphoribosyl-AMP cyclohydrolase [Novosphingobium aromaticivorans].	50.53	95	47	0	19	113	19	113	1e-26	107
rs:WP_023200999	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	46.90	113	50	1	24	126	17	129	1e-26	109
rs:WP_009451747	phosphoribosyl-AMP cyclohydrolase [Nitratireductor indicus].	52.58	97	44	1	19	113	25	121	1e-26	107
rs:WP_013547448	phosphoribosyl-AMP cyclohydrolase [Bacteroides helcogenes].	49.02	102	46	2	11	112	2	97	1e-26	109
rs:WP_013695476	phosphoribosyl-AMP cyclohydrolase [Candidatus Pelagibacter sp. IMCC9063].	50.00	98	48	1	17	113	18	115	1e-26	107
rs:WP_026713628	phosphoribosyl-ATP pyrophosphatase [Flavobacterium daejeonense].	48.08	104	51	1	11	114	1	101	1e-26	109
rs:WP_013064526	phosphoribosyl-AMP cyclohydrolase [Prevotella ruminicola].	48.04	102	47	1	11	112	3	98	1e-26	109
rs:WP_028904359	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Prevotella].	48.04	102	47	1	11	112	3	98	1e-26	109
rs:WP_000170492	phosphoribosyl-AMP cyclohydrolase [Staphylococcus aureus].	49.46	93	47	0	24	116	11	103	1e-26	109
rs:WP_022472622	phosphoribosyl-ATP diphosphatase [Sutterella sp. CAG:521].	44.66	103	56	1	14	115	6	108	1e-26	109
tr:X1M6L4_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_L01873 {ECO:0000313|EMBL:GAI10340.1}; Flags: Fragment;	51.69	89	43	0	24	112	1	89	1e-26	106
rs:WP_045501362	phosphoribosyl-ATP diphosphatase [bacterium UASB14].	52.34	107	44	2	25	131	239	338	1e-26	112
rs:WP_031926331	phosphoribosyl-ATP pyrophosphatase [Staphylococcus aureus].	49.46	93	47	0	24	116	11	103	1e-26	109
rs:WP_031925588	phosphoribosyl-ATP pyrophosphatase [Staphylococcus aureus].	49.46	93	47	0	24	116	11	103	1e-26	109
rs:WP_013406735	phosphoribosyl-ATP pyrophosphatase [Halanaerobium hydrogeniformans].	40.71	113	62	1	1	113	1	108	1e-26	109
rs:WP_027842017	phosphoribosyl-AMP cyclohydrolase [Mastigocoleus testarum].	50.00	104	50	1	19	120	25	128	1e-26	108
rs:WP_034496548	phosphoribosyl-ATP pyrophosphatase [Buttiauxella agrestis].	51.69	89	43	0	24	112	17	105	1e-26	109
rs:WP_007200530	phosphoribosyl-ATP pyrophosphatase [Fictibacillus macauensis].	48.39	93	48	0	20	112	8	100	1e-26	109
rs:WP_013572020	phosphoribosyl-AMP cyclohydrolase [Vibrio vulnificus].	51.69	89	43	0	24	112	22	110	1e-26	109
rs:WP_000186285	phosphoribosyl-AMP cyclohydrolase [Staphylococcus aureus].	49.46	93	47	0	24	116	11	103	1e-26	109
rs:WP_033935685	phosphoribosyl-AMP cyclohydrolase [Lactobacillus mucosae].	50.00	94	47	0	24	117	10	103	1e-26	106
rs:WP_045896127	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	49.44	89	45	0	24	112	17	105	1e-26	109
rs:WP_017461197	phosphoribosyl-AMP cyclohydrolase [Dyella ginsengisoli].	56.18	89	39	0	24	112	21	109	1e-26	109
tr:A0A075H3M6_9ARCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	42.86	105	59	1	11	114	1	105	1e-26	106
rs:WP_037147002	phosphoribosyl-AMP cyclohydrolase [Rhizobium sp. YS-1r].	46.15	117	61	1	17	131	22	138	1e-26	107
rs:WP_008986580	phosphoribosyl-AMP cyclohydrolase [Photobacterium leiognathi].	50.00	90	45	0	23	112	13	102	1e-26	109
rs:WP_000170495	phosphoribosyl-AMP cyclohydrolase [Staphylococcus aureus].	49.46	93	47	0	24	116	11	103	1e-26	109
rs:WP_044365497	phosphoribosyl-ATP pyrophosphatase [Vibrio fluvialis].	51.69	89	43	0	24	112	20	108	1e-26	109
rs:WP_044131528	phosphoribosyl-AMP cyclohydrolase [Thaumarchaeota archaeon SCGC AAA007-O23].	42.86	105	59	1	11	114	1	105	1e-26	106
rs:WP_007657448	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Parabacteroides].	47.78	90	47	0	23	112	9	98	1e-26	108
rs:WP_008247898	phosphoribosyl-AMP cyclohydrolase [Limnobacter sp. MED105].	49.02	102	51	1	17	117	14	115	1e-26	107
rs:WP_045208978	phosphoribosyl-ATP pyrophosphatase [Bacillus amyloliquefaciens].	45.37	108	59	0	18	125	7	114	1e-26	109
rs:WP_020330214	phosphoribosyl-AMP cyclohydrolase [Vibrio fluvialis].	51.69	89	43	0	24	112	20	108	1e-26	109
rs:WP_034039814	phosphoribosyl-ATP pyrophosphatase [Flaviramulus ichthyoenteri].	48.42	95	49	0	17	111	2	96	1e-26	108
rs:WP_047369632	phosphoribosyl-ATP pyrophosphatase [Kluyvera intermedia].	46.02	113	51	1	24	126	17	129	1e-26	108
rs:WP_001679246	phosphoribosyl-AMP cyclohydrolase, partial [Salmonella enterica].	46.90	113	50	1	24	126	17	129	2e-26	108
rs:WP_032080252	phosphoribosyl-ATP pyrophosphatase [Vibrio fluvialis].	51.69	89	43	0	24	112	20	108	2e-26	109
rs:WP_007209751	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacteroides].	49.02	102	46	2	11	112	1	96	2e-26	108
rs:WP_045026159	phosphoribosyl-ATP pyrophosphatase [Draconibacterium sp. JN14CK-3].	48.00	100	51	1	14	112	6	105	2e-26	108
rs:WP_044271852	phosphoribosyl-ATP pyrophosphatase [Candidatus Bacteroides timonensis].	49.02	102	46	2	11	112	1	96	2e-26	108
rs:WP_003894601	phosphoribosyl-AMP cyclohydrolase [Mycobacterium smegmatis].	51.58	95	46	0	18	112	11	105	2e-26	106
rs:WP_033160456	phosphoribosyl-ATP pyrophosphatase [Bacteroides cellulosilyticus].	49.02	102	46	2	11	112	1	96	2e-26	108
rs:WP_035457178	phosphoribosyl-AMP cyclohydrolase [Lactobacillus coryniformis].	49.46	93	47	0	25	117	13	105	2e-26	106
rs:WP_024372837	phosphoribosyl-ATP pyrophosphatase, partial [Vibrio natriegens].	51.69	89	43	0	24	112	22	110	2e-26	107
rs:WP_000954843	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	46.90	113	50	1	24	126	17	129	2e-26	108
rs:WP_000186282	phosphoribosyl-AMP cyclohydrolase [Staphylococcus aureus].	49.46	93	47	0	24	116	11	103	2e-26	109
rs:WP_008602551	phosphoribosyl-AMP cyclohydrolase [alpha proteobacterium JLT2015].	50.00	102	51	0	18	119	15	116	2e-26	106
rs:WP_025675863	phosphoribosyl-ATP pyrophosphatase [Paenibacillus polymyxa].	50.00	96	48	0	17	112	17	112	2e-26	110
rs:WP_033711483	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Mycobacterium avium complex (MAC)].	51.52	99	48	0	18	116	11	109	2e-26	106
rs:WP_044645046	phosphoribosyl-ATP pyrophosphatase [Paenibacillus terrae].	48.45	97	50	0	17	113	17	113	2e-26	110
rs:WP_017047733	phosphoribosyl-AMP cyclohydrolase [Vibrio ordalii].	52.81	89	42	0	24	112	22	110	2e-26	109
rs:WP_028077078	phosphoribosyl-ATP diphosphatase [Solirubrobacterales bacterium URHD0059].	47.06	102	54	0	13	114	1	102	2e-26	108
rs:WP_002051773	histidine biosynthesis bifunctional protein HisIE [Vibrio cholerae].	52.81	89	42	0	24	112	21	109	2e-26	109
rs:WP_005843464	phosphoribosyl-AMP cyclohydrolase [Prevotella dentalis].	53.93	89	41	0	24	112	10	98	2e-26	109
rs:WP_024954940	phosphoribosyl-ATP diphosphatase [Sulfurospirillum arcachonense].	51.06	94	45	1	25	117	12	105	2e-26	109
rs:WP_047103480	phosphoribosyl-ATP pyrophosphatase [Brachyspira hyodysenteriae].	44.66	103	57	0	14	116	8	110	2e-26	109
rs:WP_045690002	phosphoribosyl-ATP pyrophosphatase [Hymenobacter sp. AT01-02].	52.81	89	42	0	24	112	11	99	2e-26	109
rs:WP_022111043	histidine biosynthesis protein HisIE [Prevotella sp. CAG:604].	51.69	89	43	0	24	112	10	98	2e-26	109
rs:WP_001737947	phosphoribosyl-AMP cyclohydrolase, partial [Salmonella enterica].	51.69	89	43	0	24	112	17	105	2e-26	106
rs:WP_001973366	phosphoribosyl-AMP cyclohydrolase [Bacillus cereus].	51.11	90	44	0	24	113	8	97	2e-26	106
rs:WP_007082786	phosphoribosyl-AMP cyclohydrolase [Rhodanobacter fulvus].	50.00	102	50	1	14	114	6	107	2e-26	108
rs:WP_041851942	phosphoribosyl-ATP pyrophosphatase [Enterobacter sp. Bisph2].	46.02	113	51	1	24	126	17	129	2e-26	108
tr:A0A075FUG0_9ARCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	41.90	105	60	1	11	114	1	105	2e-26	106
rs:WP_013857090	phosphoribosyl-AMP cyclohydrolase [Vibrio anguillarum].	52.81	89	42	0	24	112	22	110	2e-26	108
rs:WP_027673270	phosphoribosyl-AMP cyclohydrolase [Agrobacterium larrymoorei].	48.72	117	54	2	19	129	24	140	2e-26	107
rs:WP_017043909	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Vibrio].	52.81	89	42	0	24	112	22	110	2e-26	108
rs:WP_023932958	histidine biosynthesis bifunctional protein HisIE [Photobacterium leiognathi].	45.79	107	57	1	23	129	13	118	2e-26	108
sp:HIS3_MYCS2	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	51.58	95	46	0	18	112	11	105	2e-26	106
rs:WP_010319247	phosphoribosyl-AMP cyclohydrolase [Vibrio ordalii].	52.81	89	42	0	24	112	22	110	2e-26	108
tr:A0A075LXA7_9EURY	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	52.81	89	41	1	25	113	18	105	2e-26	108
rs:WP_018751873	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sanguinis].	47.92	96	50	0	18	113	22	117	2e-26	109
rs:WP_000954850	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	46.90	113	50	1	24	126	17	129	2e-26	108
rs:WP_045614282	phosphoribosyl-ATP pyrophosphatase [Vibrio vulnificus].	51.69	89	43	0	24	112	22	110	2e-26	108
rs:WP_001067503	histidine biosynthesis bifunctional protein HisIE [Vibrio cholerae].	52.81	89	42	0	24	112	21	109	2e-26	108
rs:WP_010011460	phosphoribosyl-AMP cyclohydrolase [Lactobacillus coryniformis].	49.46	93	47	0	25	117	13	105	2e-26	106
tr:M7MZX8_9FLAO	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	47.52	101	48	2	11	111	24	119	2e-26	109
tr:D5BQW7_PUNMI	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	47.87	94	49	0	19	112	16	109	2e-26	108
rs:WP_028697515	phosphoribosyl-AMP cyclohydrolase, partial [Pseudomonas monteilii].	54.26	94	42	1	38	130	2	95	2e-26	106
rs:WP_031894336	phosphoribosyl-ATP pyrophosphatase, partial [Staphylococcus aureus].	49.46	93	47	0	24	116	11	103	2e-26	108
tr:A0A075JK39_9BACI	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	47.22	108	56	1	13	119	1	108	2e-26	108
rs:WP_012960406	phosphoribosyl-ATP pyrophosphatase [Bacillus pseudofirmus].	49.47	95	48	0	18	112	6	100	2e-26	108
rs:WP_045136205	phosphoribosyl-AMP cyclohydrolase [Lactobacillus paracasei].	48.11	106	54	1	17	121	3	108	2e-26	106
sp:HIS2_SALTI	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	46.90	113	50	1	24	126	17	129	2e-26	108
rs:WP_029951551	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Burkholderia].	50.48	105	50	1	19	121	21	125	2e-26	107
rs:WP_036032408	phosphoribosyl-AMP cyclohydrolase [Burkholderia gladioli].	50.48	105	50	1	19	121	21	125	2e-26	107
rs:WP_041861060	phosphoribosyl-ATP pyrophosphatase [Candidatus Puniceispirillum marinum].	47.87	94	49	0	19	112	11	104	2e-26	108
rs:WP_017422250	phosphoribosyl-AMP cyclohydrolase [Vibrio vulnificus].	51.69	89	43	0	24	112	22	110	2e-26	108
rs:WP_042284234	phosphoribosyl-AMP cyclohydrolase [Burkholderia gladioli].	50.48	105	50	1	19	121	33	137	2e-26	107
rs:WP_031458052	imidazole glycerol phosphate synthase [Chloroflexus sp. MS-G].	52.17	92	44	0	22	113	6	97	2e-26	108
rs:WP_045082688	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Photobacterium].	50.00	90	45	0	23	112	13	102	2e-26	108
rs:WP_042358276	phosphoribosyl-ATP pyrophosphatase [Geomicrobium sp. JCM 19055].	48.96	96	49	0	17	112	5	100	2e-26	108
rs:WP_028282101	phosphoribosyl-ATP pyrophosphatase [Olleya marilimosa].	47.42	97	49	1	17	111	2	98	2e-26	108
rs:WP_006264200	phosphoribosyl-AMP cyclohydrolase [Myroides odoratimimus].	44.17	120	57	2	18	127	5	124	2e-26	108
rs:WP_023212538	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	46.90	113	50	1	24	126	17	129	2e-26	108
rs:WP_009062018	phosphoribosyl-AMP cyclohydrolase [Methylacidiphilum fumariolicum].	47.12	104	54	1	19	121	17	120	2e-26	107
rs:WP_043000208	phosphoribosyl-ATP pyrophosphatase [Citrobacter sp. MGH 55].	47.79	113	49	1	24	126	17	129	2e-26	108
rs:WP_039981726	phosphoribosyl-ATP pyrophosphatase [Vibrio sagamiensis].	50.00	90	45	0	23	112	21	110	2e-26	108
sp:HIS3_HALS3	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	47.66	107	56	0	11	117	8	114	2e-26	106
rs:WP_014488950	phosphoribosyl-ATP pyrophosphatase [Brachyspira intermedia].	44.66	103	57	0	14	116	8	110	2e-26	109
rs:WP_013215749	phosphoribosyl-AMP cyclohydrolase [Hyphomicrobium denitrificans].	53.61	97	43	1	19	113	26	122	2e-26	107
rs:WP_046148489	phosphoribosyl-ATP pyrophosphatase [Parabacteroides sp. HGS0025].	47.78	90	47	0	23	112	9	98	2e-26	108
rs:WP_009640152	phosphoribosyl-AMP cyclohydrolase, partial [Propionibacterium sp. 434-HC2].	58.97	78	32	0	35	112	2	79	2e-26	105
rs:WP_038938957	phosphoribosyl-ATP pyrophosphatase [Vibrio vulnificus].	51.69	89	43	0	24	112	22	110	2e-26	108
rs:WP_039449002	phosphoribosyl-ATP pyrophosphatase [Vibrio vulnificus].	51.69	89	43	0	24	112	22	110	2e-26	108
rs:WP_021019026	phosphoribosyl-AMP cyclohydrolase [Vibrio gazogenes].	55.06	89	40	0	24	112	21	109	2e-26	108
rs:WP_037577133	phosphoribosyl-ATP pyrophosphatase [Staphylococcus chromogenes].	52.69	93	44	0	24	116	10	102	2e-26	108
rs:WP_026969222	phosphoribosyl-ATP pyrophosphatase [Algoriphagus terrigena].	52.81	89	42	0	24	112	13	101	2e-26	108
rs:WP_047062979	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	49.44	89	45	0	24	112	17	105	2e-26	108
rs:WP_045594469	phosphoribosyl-ATP pyrophosphatase [Vibrio vulnificus].	51.69	89	43	0	24	112	22	110	2e-26	108
rs:WP_039067399	phosphoribosyl-ATP pyrophosphatase [Staphylococcus xylosus].	46.00	100	54	0	24	123	11	110	2e-26	108
rs:WP_021020230	phosphoribosyl-AMP cyclohydrolase [Vibrio gazogenes].	55.06	89	40	0	24	112	21	109	2e-26	108
rs:WP_012906367	phosphoribosyl-AMP cyclohydrolase [Citrobacter rodentium].	45.13	113	52	1	24	126	17	129	2e-26	108
rs:WP_021373443	phosphoribosyl-ATP diphosphatase [Peptoclostridium difficile].	44.14	111	62	0	17	127	19	129	2e-26	108
rs:WP_022425664	phosphoribosyl-ATP diphosphatase [Catenibacterium sp. CAG:290].	50.54	93	46	0	24	116	10	102	2e-26	108
rs:WP_045403512	phosphoribosyl-ATP pyrophosphatase [Vibrio sp. 090810a].	51.69	89	43	0	24	112	22	110	2e-26	108
rs:WP_035794308	hypothetical protein [Butyrivibrio sp. WCD3002].	50.00	96	48	0	18	113	227	322	2e-26	111
rs:WP_039255802	imidazole glycerol phosphate synthase [Clostridium novyi].	52.22	90	43	0	24	113	262	351	2e-26	111
rs:WP_007525786	phosphoribosyl-AMP cyclohydrolase [Haemophilus sputorum].	40.71	113	66	1	13	124	2	114	2e-26	108
rs:WP_045444601	phosphoribosyl-ATP pyrophosphatase [Citrobacter sp. S-77].	46.90	113	50	1	24	126	17	129	2e-26	108
rs:WP_038964470	phosphoribosyl-ATP pyrophosphatase [Vibrio vulnificus].	51.69	89	43	0	24	112	22	110	2e-26	108
rs:WP_047322951	phosphoribosyl-AMP cyclohydrolase [Mycobacterium nebraskense].	52.63	95	45	0	18	112	11	105	2e-26	106
rs:WP_045348858	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	49.44	89	45	0	24	112	17	105	2e-26	108
rs:WP_039553325	phosphoribosyl-ATP pyrophosphatase [Vibrio vulnificus].	51.69	89	43	0	24	112	22	110	2e-26	108
rs:WP_014204891	phosphoribosyl-AMP cyclohydrolase [Vibrio furnissii].	51.69	89	43	0	24	112	20	108	2e-26	108
rs:WP_032623979	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae complex].	49.44	89	45	0	24	112	17	105	2e-26	108
rs:WP_046619196	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	49.44	89	45	0	24	112	17	105	2e-26	108
rs:WP_038557947	phosphoribosyl-ATP pyrophosphatase [Draconibacterium orientale].	48.00	100	51	1	14	112	6	105	2e-26	108
rs:WP_026755990	phosphoribosyl-ATP pyrophosphatase [Sediminibacter sp. Hel_I_10].	52.27	88	42	0	24	111	10	97	2e-26	108
rs:WP_029036839	phosphoribosyl-ATP pyrophosphatase [Salinimicrobium xinjiangense].	51.14	88	43	0	24	111	11	98	2e-26	108
rs:WP_047056192	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	50.56	89	44	0	24	112	17	105	2e-26	108
sp:HIS2_VIBVU	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	51.69	89	43	0	24	112	22	110	2e-26	108
rs:WP_007411718	phosphoribosyl-AMP cyclohydrolase [Prevotella sp. MSX73].	49.02	102	46	1	11	112	3	98	2e-26	108
rs:WP_000186286	phosphoribosyl-AMP cyclohydrolase [Staphylococcus aureus].	49.46	93	47	0	24	116	11	103	2e-26	108
tr:C2PTE6_BACCE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	52.81	89	42	0	25	113	1	89	2e-26	105
rs:WP_023986480	phosphoribosyl-ATP pyrophosphatase [Paenibacillus polymyxa].	48.45	97	50	0	17	113	17	113	2e-26	109
rs:WP_040074921	phosphoribosyl-ATP pyrophosphatase [Enterobacteriaceae bacterium ATCC 29904].	46.90	113	50	1	24	126	17	129	2e-26	108
rs:WP_039283782	imidazole glycerol phosphate synthase [Clostridium botulinum].	52.22	90	43	0	24	113	262	351	2e-26	111
rs:WP_022975123	phosphoribosyl-AMP cyclohydrolase [Nevskia ramosa].	50.98	102	49	1	19	119	28	129	3e-26	107
rs:WP_008271626	phosphoribosyl-AMP cyclohydrolase [Flavobacteriales bacterium ALC-1].	46.39	97	50	1	17	111	2	98	3e-26	108
rs:WP_040135777	phosphoribosyl-ATP pyrophosphatase [Pseudoalteromonas sp. OCN003].	47.57	103	53	1	11	112	3	105	3e-26	108
rs:WP_012789504	phosphoribosyl-AMP cyclohydrolase [Chitinophaga pinensis].	51.14	88	43	0	24	111	15	102	3e-26	108
rs:WP_034539884	phosphoribosyl-AMP cyclohydrolase [Lactobacillus mucosae].	50.00	94	47	0	24	117	10	103	3e-26	106
rs:WP_014450181	histidine biosynthesis bifunctional protein [Leptospirillum ferrooxidans].	50.00	100	50	0	20	119	7	106	3e-26	108
rs:WP_007776200	phosphoribosyl-AMP cyclohydrolase [Mycobacterium colombiense].	50.48	105	52	0	18	122	11	115	3e-26	106
rs:WP_038028554	phosphoribosyl-ATP pyrophosphatase [Thermonema rossianum].	46.60	103	53	1	13	113	8	110	3e-26	108
rs:WP_031532118	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacteroides].	51.04	96	46	1	18	112	3	98	3e-26	108
rs:WP_019470087	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Staphylococcus].	50.54	93	46	0	24	116	10	102	3e-26	108
rs:WP_014971133	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Exiguobacterium].	50.00	100	49	1	18	117	4	102	3e-26	105
sp:HIS3_MYCPA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	51.58	95	46	0	18	112	11	105	3e-26	105
rs:WP_000954842	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	51.69	89	43	0	24	112	17	105	3e-26	108
rs:WP_003367613	imidazole glycerol phosphate synthase [Clostridium botulinum].	52.22	90	43	0	24	113	262	351	3e-26	110
rs:WP_036140587	phosphoribosyl-ATP pyrophosphatase [Luteibacter sp. 9135].	56.18	89	39	0	24	112	14	102	3e-26	108
rs:WP_025684762	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. 1-49].	48.45	97	50	0	17	113	17	113	3e-26	109
tr:D1CF76_THET1	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00006950}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	49.51	103	51	1	18	119	14	116	3e-26	110
rs:WP_040564209	phosphoribosyl-ATP pyrophosphatase [Kingella denitrificans].	42.45	106	60	1	13	117	2	107	3e-26	108
rs:WP_029283435	phosphoribosyl-ATP pyrophosphatase [Pedobacter sp. R20-19].	46.67	105	55	1	11	114	1	105	3e-26	108
rs:WP_009132258	histidine biosynthesis HisIE [Bacteroides oleiciplenus].	48.04	102	47	2	11	112	1	96	3e-26	108
rs:WP_044532491	phosphoribosyl-ATP pyrophosphatase [Bacteroides intestinalis].	48.04	102	47	2	11	112	1	96	3e-26	108
rs:WP_036782263	phosphoribosyl-ATP pyrophosphatase [Pontibacillus chungwhensis].	46.00	100	54	0	13	112	1	100	3e-26	108
rs:WP_046737212	phosphoribosyl-AMP cyclohydrolase [Dehalogenimonas sp. WBC-2].	50.00	96	48	0	18	113	8	103	3e-26	105
rs:WP_012371226	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Exiguobacterium].	50.00	100	49	1	18	117	4	102	3e-26	105
rs:WP_025903430	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Tatumella].	47.37	95	50	0	24	118	17	111	3e-26	108
rs:WP_014939638	phosphoribosyl-AMP cyclohydrolase [Lactobacillus buchneri].	49.46	93	47	0	24	116	11	103	3e-26	105
rs:WP_007665007	phosphoribosyl-AMP cyclohydrolase [Bacteroides intestinalis].	48.04	102	47	2	11	112	1	96	3e-26	108
rs:WP_023218926	phosphoribosyl-AMP cyclohydrolase [Salmonella enterica].	46.90	113	50	1	24	126	17	129	3e-26	108
rs:WP_005705283	phosphoribosyl-AMP cyclohydrolase [Haemophilus parahaemolyticus].	42.45	106	60	1	13	117	2	107	3e-26	108
rs:WP_017427879	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Paenibacillus].	50.00	96	48	0	17	112	17	112	3e-26	109
rs:WP_026740439	phosphoribosyl-ATP pyrophosphatase [Lonsdalea quercina].	51.69	89	43	0	24	112	17	105	3e-26	108
tr:S4NQ11_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	56.47	85	35	1	38	120	1	85	3e-26	105
rs:WP_006962772	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Vibrio].	51.69	89	43	0	24	112	22	110	3e-26	108
rs:WP_042284254	phosphoribosyl-ATP pyrophosphatase [Citrobacter sedlakii].	50.56	89	44	0	24	112	17	105	3e-26	108
rs:WP_040102400	phosphoribosyl-ATP pyrophosphatase [Paenibacillus polymyxa].	50.00	96	48	0	17	112	17	112	3e-26	109
sp:HIS3_DECAR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	47.71	109	50	3	12	114	3	110	3e-26	106
rs:WP_008627446	phosphoribosyl-AMP cyclohydrolase [Paraprevotella xylaniphila].	51.69	89	43	0	24	112	10	98	3e-26	108
rs:WP_014279163	phosphoribosyl-ATP pyrophosphatase [Paenibacillus terrae].	48.45	97	50	0	17	113	17	113	3e-26	109
rs:WP_016820120	phosphoribosyl-ATP pyrophosphatase [Paenibacillus polymyxa].	50.00	96	48	0	17	112	17	112	3e-26	109
rs:WP_025363695	phosphoribosyl-ATP pyrophosphatase [Paenibacillus polymyxa].	50.00	96	48	0	17	112	17	112	3e-26	109
rs:WP_004743970	phosphoribosyl-AMP cyclohydrolase [Vibrio tubiashii].	51.69	89	43	0	24	112	22	110	3e-26	108
rs:WP_042292999	phosphoribosyl-ATP pyrophosphatase [Nonlabens ulvanivorans].	49.45	91	46	0	22	112	9	99	3e-26	108
rs:WP_006846460	phosphoribosyl-AMP cyclohydrolase [Prevotella copri].	52.22	90	43	0	23	112	9	98	3e-26	108
rs:WP_023280322	histidine biosynthesis HisIE [Klebsiella pneumoniae].	51.69	89	43	0	24	112	13	101	3e-26	108
rs:WP_006811215	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Enterobacter].	49.44	89	45	0	24	112	17	105	3e-26	108
rs:WP_040320652	phosphoribosyl-AMP cyclohydrolase [Aeromicrobium marinum].	48.42	95	49	0	18	112	15	109	3e-26	105
rs:WP_004189165	phosphoribosyl-AMP cyclohydrolase [Klebsiella pneumoniae].	51.69	89	43	0	24	112	13	101	3e-26	108
rs:WP_000186281	phosphoribosyl-AMP cyclohydrolase [Staphylococcus aureus].	49.46	93	47	0	24	116	11	103	3e-26	108
rs:WP_019685792	phosphoribosyl-ATP pyrophosphatase [Paenibacillus polymyxa].	50.00	96	48	0	17	112	17	112	3e-26	109
tr:A0A098EMC7_9BACL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	48.45	97	50	0	16	112	2	98	3e-26	108
rs:WP_026916290	phosphoribosyl-ATP pyrophosphatase [Gramella portivictoriae].	46.53	101	51	1	11	111	1	98	3e-26	108
gp:CP007339_1297	phosphoribosyl-ATP pyrophosphatase [Salmonella enterica subsp. enterica serovar Enteritidis str.]	51.69	89	43	0	24	112	17	105	3e-26	108
rs:WP_044267038	phosphoribosyl-ATP pyrophosphatase [Citrobacter amalonaticus].	46.90	113	50	1	24	126	17	129	3e-26	108
rs:WP_004918003	phosphoribosyl-AMP cyclohydrolase [Providencia stuartii].	50.56	89	44	0	24	112	17	105	3e-26	108
rs:WP_032441359	phosphoribosyl-ATP pyrophosphatase [Klebsiella pneumoniae].	51.69	89	43	0	24	112	13	101	3e-26	108
rs:WP_036107974	phosphoribosyl-ATP pyrophosphatase [Mangrovibacter sp. MFB070].	50.56	89	44	0	24	112	17	105	3e-26	108
rs:WP_023290360	MULTISPECIES: histidine biosynthesis HisIE [Klebsiella].	51.69	89	43	0	24	112	13	101	3e-26	108
rs:WP_031783710	phosphoribosyl-ATP pyrophosphatase [Staphylococcus aureus].	49.46	93	47	0	24	116	11	103	3e-26	108
rs:WP_042711633	phosphoribosyl-ATP pyrophosphatase [Klebsiella cf. planticola B43].	50.56	89	44	0	24	112	17	105	3e-26	108
rs:WP_029093635	phosphoribosyl-ATP pyrophosphatase [Budvicia aquatica].	47.92	96	50	0	23	118	16	111	3e-26	108
rs:WP_034289544	phosphoribosyl-ATP diphosphatase [Helicobacter sp. MIT 11-5569].	48.94	94	48	0	24	117	15	108	3e-26	108
rs:WP_028375303	phosphoribosyl-ATP pyrophosphatase [Leeuwenhoekiella sp. Hel_I_48].	50.00	92	46	0	20	111	5	96	3e-26	108
rs:WP_025714192	phosphoribosyl-ATP pyrophosphatase [Klebsiella sp. 10982].	51.69	89	43	0	24	112	13	101	3e-26	108
rs:WP_031825607	phosphoribosyl-ATP pyrophosphatase [Staphylococcus aureus].	49.46	93	47	0	24	116	11	103	3e-26	108
sp:HIS2_STAAM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	49.46	93	47	0	24	116	11	103	3e-26	108
rs:WP_029549474	phosphoribosyl-ATP pyrophosphatase [Staphylococcus aureus].	49.46	93	47	0	24	116	6	98	3e-26	108
rs:WP_022854882	phosphoribosyl-AMP cyclohydrolase [Thermodesulfobacterium thermophilum].	44.55	110	60	1	23	131	11	120	3e-26	106
rs:WP_022672525	phosphoribosyl-AMP cyclohydrolase [Sphingopyxis baekryungensis].	48.98	98	50	0	19	116	14	111	3e-26	105
rs:WP_031907181	histidine biosynthesis bifunctional protein HisIE [Staphylococcus aureus].	49.46	93	47	0	24	116	11	103	3e-26	108
rs:WP_000186287	phosphoribosyl-AMP cyclohydrolase [Staphylococcus aureus].	49.46	93	47	0	24	116	11	103	3e-26	108
rs:WP_021346532	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Elizabethkingia].	47.83	92	48	0	21	112	8	99	3e-26	108
rs:WP_000954854	phosphoribosyl-AMP cyclohydrolase [Salmonella bongori].	46.90	113	50	1	24	126	17	129	3e-26	108
rs:WP_008622280	phosphoribosyl-AMP cyclohydrolase [Paraprevotella clara].	50.56	89	44	0	24	112	10	98	3e-26	108
rs:WP_024566996	phosphoribosyl-ATP pyrophosphatase [Elizabethkingia anophelis].	47.83	92	48	0	21	112	8	99	3e-26	107
rs:WP_006499768	phosphoribosyl-AMP cyclohydrolase [Lactobacillus mucosae].	48.94	94	48	0	24	117	10	103	3e-26	105
rs:WP_011706043	phosphoribosyl-AMP cyclohydrolase [Aeromonas hydrophila].	51.69	89	43	0	24	112	23	111	3e-26	108
rs:WP_021713063	histidine biosynthesis bifunctional protein HisIE [Vibrio ezurae].	52.81	89	42	0	24	112	22	110	3e-26	108
rs:WP_000186288	phosphoribosyl-AMP cyclohydrolase [Staphylococcus aureus].	49.46	93	47	0	24	116	11	103	3e-26	108
rs:WP_045339079	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	49.44	89	45	0	24	112	17	105	3e-26	108
rs:WP_023300530	histidine biosynthesis HisIE [Enterobacter cloacae].	49.44	89	45	0	24	112	17	105	3e-26	108
rs:WP_029519003	phosphoribosyl-ATP pyrophosphatase [Paenibacillus polymyxa].	48.45	97	50	0	17	113	17	113	3e-26	108
rs:WP_032417328	phosphoribosyl-ATP pyrophosphatase [Klebsiella pneumoniae].	51.69	89	43	0	24	112	13	101	3e-26	108
rs:WP_008078828	phosphoribosyl-AMP cyclohydrolase [Vibrio sinaloensis].	51.69	89	43	0	24	112	22	110	3e-26	108
rs:WP_045974406	phosphoribosyl-ATP pyrophosphatase [Vibrio neptunius].	51.69	89	43	0	24	112	22	110	3e-26	108
rs:WP_045394373	phosphoribosyl-ATP pyrophosphatase [Vibrio rotiferianus].	51.69	89	43	0	24	112	22	110	3e-26	108
rs:WP_027066931	phosphoribosyl-ATP pyrophosphatase [Maribacter sp. Hel_I_7].	43.22	118	57	1	11	118	1	118	3e-26	108
rs:WP_001644997	histidine biosynthesis HisIE [Staphylococcus aureus].	49.46	93	47	0	24	116	11	103	3e-26	108
rs:WP_000170494	phosphoribosyl-AMP cyclohydrolase [Staphylococcus aureus].	49.46	93	47	0	24	116	11	103	3e-26	108
rs:WP_021980607	phosphoribosyl-ATP diphosphatase [Paraprevotella clara CAG:116].	50.56	89	44	0	24	112	10	98	3e-26	108
tr:E2S935_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	48.42	95	49	0	18	112	26	120	4e-26	105
rs:WP_005378160	phosphoribosyl-AMP cyclohydrolase [Vibrio alginolyticus].	51.69	89	43	0	24	112	22	110	4e-26	108
gp:CP010941_36	phosphoribosyl-ATP pyrophosphatase [Staphylococcus aureus]	49.46	93	47	0	24	116	11	103	4e-26	108
rs:WP_005390893	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Vibrio harveyi group].	51.69	89	43	0	24	112	22	110	4e-26	108
rs:WP_033905093	phosphoribosyl-ATP pyrophosphatase [Vibrio sp. OY15].	51.69	89	43	0	24	112	22	110	4e-26	108
rs:WP_040231906	phosphoribosyl-ATP pyrophosphatase [Citrobacter sp. CIP 55.13].	45.13	113	52	1	24	126	17	129	4e-26	108
rs:WP_002469240	histidine biosynthesis bifunctional protein HisIE [Staphylococcus epidermidis].	47.87	94	49	0	24	117	10	103	4e-26	108
rs:WP_017821718	phosphoribosyl-AMP cyclohydrolase [Vibrio alginolyticus].	51.69	89	43	0	24	112	22	110	4e-26	108
rs:WP_038214838	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Vibrio].	51.69	89	43	0	24	112	22	110	4e-26	108
sp:HIS2_STAES	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	47.87	94	49	0	24	117	10	103	4e-26	108
rs:WP_040117834	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	49.44	89	45	0	24	112	17	105	4e-26	108
rs:WP_005437220	phosphoribosyl-AMP cyclohydrolase [Vibrio harveyi].	51.69	89	43	0	24	112	22	110	4e-26	108
rs:WP_044038494	phosphoribosyl-AMP cyclohydrolase [Clostridium sp. M2/40].	46.23	106	51	1	11	116	1	100	4e-26	105
rs:WP_046187017	phosphoribosyl-AMP cyclohydrolase [Mycobacterium nebraskense].	52.63	95	45	0	18	112	11	105	4e-26	105
rs:WP_038189398	phosphoribosyl-ATP pyrophosphatase [Vibrio sinaloensis].	51.69	89	43	0	24	112	22	110	4e-26	108
rs:WP_005533681	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Vibrio].	51.69	89	43	0	24	112	22	110	4e-26	108
rs:WP_016350788	phosphoribosyl-AMP cyclohydrolase [Aeromonas hydrophila].	51.69	89	43	0	24	112	23	111	4e-26	108
rs:WP_045026745	phosphoribosyl-ATP pyrophosphatase [Photobacterium phosphoreum].	50.00	90	45	0	23	112	13	102	4e-26	108
rs:WP_017634687	phosphoribosyl-AMP cyclohydrolase [Vibrio sp. 712i1].	51.69	89	43	0	24	112	22	110	4e-26	108
rs:WP_002473510	phosphoribosyl-AMP cyclohydrolase [Staphylococcus epidermidis].	47.87	94	49	0	24	117	10	103	4e-26	108
rs:WP_001070390	phosphoribosyl-AMP cyclohydrolase [Vibrio cholerae].	51.69	89	43	0	24	112	21	109	4e-26	108
rs:WP_039295112	phosphoribosyl-ATP pyrophosphatase [Cedecea neteri].	51.69	89	43	0	24	112	17	105	4e-26	108
rs:WP_042067377	phosphoribosyl-ATP pyrophosphatase [Aeromonas hydrophila].	51.69	89	43	0	24	112	23	111	4e-26	108
rs:WP_005389826	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Vibrio].	51.69	89	43	0	24	112	22	110	4e-26	108
rs:WP_006506050	phosphoribosyl-ATP pyrophosphatase [Catenibacterium mitsuokai].	49.46	93	47	0	24	116	10	102	4e-26	108
rs:WP_002912260	phosphoribosyl-AMP cyclohydrolase [Klebsiella pneumoniae].	51.69	89	43	0	24	112	13	101	4e-26	107
rs:WP_042051756	phosphoribosyl-ATP pyrophosphatase [Aeromonas dhakensis].	51.69	89	43	0	24	112	23	111	4e-26	108
rs:WP_038882807	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Vibrio].	51.69	89	43	0	24	112	22	110	4e-26	108
rs:WP_002446921	phosphoribosyl-AMP cyclohydrolase [Staphylococcus epidermidis].	50.55	91	45	0	24	114	10	100	4e-26	108
rs:WP_009705761	phosphoribosyl-AMP cyclohydrolase [Vibrio sp. HENC-03].	51.69	89	43	0	24	112	22	110	4e-26	108
rs:WP_029940750	phosphoribosyl-ATP pyrophosphatase [Sphingomonas astaxanthinifaciens].	52.13	94	45	0	24	117	15	108	4e-26	108
rs:WP_045039293	phosphoribosyl-ATP pyrophosphatase [Photobacterium iliopiscarium].	51.11	90	44	0	23	112	13	102	4e-26	108
rs:WP_005450749	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Vibrio].	51.69	89	43	0	24	112	22	110	4e-26	108
rs:WP_002499102	phosphoribosyl-AMP cyclohydrolase [Staphylococcus epidermidis].	47.87	94	49	0	24	117	10	103	4e-26	108
rs:WP_038481331	phosphoribosyl-ATP pyrophosphatase [Cedecea neteri].	51.69	89	43	0	24	112	17	105	4e-26	108
rs:WP_047053494	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	49.44	89	45	0	24	112	17	105	4e-26	108
rs:WP_019967609	phosphoribosyl-AMP cyclohydrolase [Prevotella maculosa].	48.96	96	48	1	18	112	3	98	4e-26	108
rs:WP_008566581	phosphoribosyl-AMP cyclohydrolase [Prevotella maculosa].	48.96	96	48	1	18	112	3	98	4e-26	108
rs:WP_044800032	phosphoribosyl-ATP pyrophosphatase [Aeromonas hydrophila].	51.69	89	43	0	24	112	23	111	4e-26	108
rs:WP_020196969	phosphoribosyl-AMP cyclohydrolase [Vibrio owensii].	51.69	89	43	0	24	112	22	110	4e-26	108
rs:WP_039472823	phosphoribosyl-ATP pyrophosphatase [Vibrio sinaloensis].	51.69	89	43	0	24	112	22	110	4e-26	108
rs:WP_017030323	phosphoribosyl-AMP cyclohydrolase [Vibrio breoganii].	52.81	89	42	0	24	112	22	110	4e-26	108
sp:HIS2_STAEQ	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	47.87	94	49	0	24	117	10	103	4e-26	108
rs:WP_008496056	phosphoribosyl-AMP cyclohydrolase [Planococcus halocryophilus].	45.54	101	55	0	16	116	2	102	4e-26	108
rs:WP_002434833	phosphoribosyl-AMP cyclohydrolase [Escherichia hermannii].	43.24	111	57	1	2	112	1	105	4e-26	108
rs:WP_045420265	phosphoribosyl-ATP pyrophosphatase, partial [Vibrio jasicida].	51.69	89	43	0	24	112	22	110	4e-26	108
rs:WP_001572816	histidine biosynthesis HisIE [Escherichia coli].	46.02	113	51	1	24	126	13	125	4e-26	107
rs:WP_021298745	histidine biosynthesis bifunctional protein HisIE [Staphylococcus epidermidis].	47.87	94	49	0	24	117	10	103	4e-26	108
rs:WP_043171379	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Aeromonas].	51.69	89	43	0	24	112	23	111	4e-26	108
rs:WP_017764441	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Aeromonas].	51.69	89	43	0	24	112	23	111	4e-26	108
rs:WP_032612346	phosphoribosyl-ATP pyrophosphatase [Leclercia adecarboxylata].	45.13	113	52	1	24	126	17	129	4e-26	107
rs:WP_035168542	phosphoribosyl-AMP cyclohydrolase [Lactobacillus curieae].	50.54	93	46	0	24	116	11	103	4e-26	105
tr:A0A075I5S1_9ARCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	41.90	105	60	1	11	114	1	105	4e-26	105
rs:WP_032508322	phosphoribosyl-ATP pyrophosphatase [Peptoclostridium difficile].	44.14	111	62	0	17	127	3	113	4e-26	108
rs:WP_031462591	phosphoribosyl-ATP pyrophosphatase [Paenibacillus polymyxa].	51.06	94	46	0	19	112	19	112	4e-26	108
rs:WP_045789722	phosphoribosyl-ATP pyrophosphatase [Aeromonas hydrophila].	51.69	89	43	0	24	112	23	111	4e-26	108
rs:WP_036512881	phosphoribosyl-ATP pyrophosphatase [Oceanicaulis sp. HL-87].	55.06	89	40	0	24	112	20	108	4e-26	108
rs:WP_020712749	phosphoribosyl-AMP cyclohydrolase [Acidobacteriaceae bacterium KBS 89].	49.02	102	49	2	14	112	3	104	4e-26	105
rs:WP_017464379	phosphoribosyl-AMP cyclohydrolase [Staphylococcus epidermidis].	47.87	94	49	0	24	117	10	103	4e-26	108
rs:WP_010633928	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Aeromonas].	51.69	89	43	0	24	112	23	111	4e-26	108
rs:WP_020746208	phosphoribosyl-AMP cyclohydrolase [Alteromonas macleodii].	51.11	90	44	0	24	113	18	107	4e-26	107
tr:A0A031K8N3_9SPHN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	49.47	95	48	0	19	113	15	109	4e-26	105
rs:WP_003334368	phosphoribosyl-ATP pyrophosphatase [Brevibacillus laterosporus].	50.00	102	51	0	18	119	10	111	4e-26	108
rs:WP_017782810	phosphoribosyl-AMP cyclohydrolase [Aeromonas hydrophila].	51.69	89	43	0	24	112	23	111	4e-26	108
rs:WP_017408367	phosphoribosyl-AMP cyclohydrolase [Aeromonas hydrophila].	51.69	89	43	0	24	112	23	111	4e-26	108
rs:WP_000186279	phosphoribosyl-AMP cyclohydrolase [Staphylococcus aureus].	48.39	93	48	0	24	116	11	103	4e-26	108
rs:WP_037565826	phosphoribosyl-ATP pyrophosphatase [Staphylococcus agnetis].	49.46	93	47	0	24	116	10	102	4e-26	108
rs:WP_023306558	MULTISPECIES: histidine biosynthesis HisIE [Enterobacter].	49.44	89	45	0	24	112	17	105	4e-26	107
rs:WP_023406501	hypothetical protein [uncultured Desulfofustis sp. PB-SRB1].	45.71	105	55	2	13	116	2	105	4e-26	105
rs:WP_009165913	phosphoribosyl-ATP pyrophosphatase [Pyramidobacter piscolens].	49.47	95	48	0	18	112	7	101	4e-26	108
rs:WP_028458435	imidazole glycerol phosphate synthase [Chloroflexus sp. Y-396-1].	50.00	94	47	0	20	113	4	97	4e-26	107
rs:WP_039213802	phosphoribosyl-ATP pyrophosphatase [Aeromonas hydrophila].	51.69	89	43	0	24	112	23	111	4e-26	108
rs:WP_023314451	histidine biosynthesis HisIE [Enterobacter cloacae].	49.44	89	45	0	24	112	17	105	4e-26	107
rs:WP_008349657	phosphoribosyl-ATP pyrophosphatase [Thiovulum sp. ES].	46.94	98	52	0	24	121	12	109	4e-26	108
rs:WP_017778978	phosphoribosyl-AMP cyclohydrolase [Aeromonas hydrophila].	51.69	89	43	0	24	112	23	111	4e-26	108
rs:WP_002477263	histidine biosynthesis HisIE [Staphylococcus epidermidis].	47.87	94	49	0	24	117	10	103	4e-26	108
rs:WP_024945357	phosphoribosyl-ATP pyrophosphatase [Aeromonas hydrophila].	51.69	89	43	0	24	112	23	111	4e-26	108
rs:WP_039721541	phosphoribosyl-AMP cyclohydrolase [Methylacidiphilum kamchatkense].	46.15	104	55	1	19	121	17	120	4e-26	106
rs:WP_027868468	phosphoribosyl-ATP pyrophosphatase [Eubacterium sp. AB3007].	50.53	95	47	0	18	112	6	100	4e-26	108
rs:WP_047354509	phosphoribosyl-ATP pyrophosphatase [Enterobacter sp. GN02315].	49.44	89	45	0	24	112	17	105	4e-26	107
tr:F1Z9A0_9SPHN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	51.52	99	46	2	28	124	3	101	4e-26	105
tr:U6BC42_9BACL	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	49.02	102	51	1	16	117	2	102	4e-26	105
sp:HIS3_MYCA1	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	51.58	95	46	0	18	112	11	105	4e-26	105
rs:WP_032431699	phosphoribosyl-ATP pyrophosphatase [Klebsiella pneumoniae].	51.69	89	43	0	24	112	13	101	4e-26	107
tr:A0A075H5T6_9ARCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	44.12	102	51	1	11	112	9	104	4e-26	105
rs:WP_014857448	phosphoribosyl-AMP cyclohydrolase [Melioribacter roseus].	51.11	90	44	0	23	112	13	102	4e-26	107
rs:WP_018973695	hypothetical protein [Rudaea cellulosilytica].	47.75	111	53	2	12	121	3	109	4e-26	107
rs:WP_018039008	hypothetical protein [alpha proteobacterium SCGC AB-629-G21].	47.62	105	54	1	17	120	18	122	4e-26	106
rs:WP_045906554	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	49.44	89	45	0	24	112	17	105	5e-26	107
rs:WP_010348666	phosphoribosyl-ATP pyrophosphatase [Paenibacillus peoriae].	50.00	96	48	0	17	112	17	112	5e-26	108
rs:WP_036523095	phosphoribosyl-AMP cyclohydrolase [Novosphingobium resinovorum].	49.47	95	48	0	19	113	18	112	5e-26	105
rs:WP_020897117	phosphoribosyl-AMP cyclohydrolase [Winogradskyella psychrotolerans].	47.25	91	48	0	21	111	8	98	5e-26	107
rs:WP_015963861	phosphoribosyl-AMP cyclohydrolase [Enterobacteriaceae bacterium strain FGI 57].	46.02	113	51	1	24	126	13	125	5e-26	107
rs:WP_039304587	phosphoribosyl-ATP pyrophosphatase [Cedecea neteri].	51.69	89	43	0	24	112	17	105	5e-26	107
tr:A0A049D790_MYCAV	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	51.58	95	46	0	18	112	10	104	5e-26	105
rs:WP_017784284	phosphoribosyl-AMP cyclohydrolase [Aeromonas hydrophila].	51.69	89	43	0	24	112	23	111	5e-26	108
rs:WP_000186278	histidine biosynthesis bifunctional protein HisIE [Staphylococcus aureus].	48.39	93	48	0	24	116	11	103	5e-26	107
rs:WP_009893118	phosphoribosyl-ATP pyrophosphatase [Peptoclostridium difficile].	44.14	111	62	0	17	127	19	129	5e-26	108
tr:A0A031IGG9_9BACL	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	49.02	102	51	1	16	117	2	102	5e-26	105
rs:WP_024941745	phosphoribosyl-ATP pyrophosphatase [Aeromonas hydrophila].	51.69	89	43	0	24	112	23	111	5e-26	108
rs:WP_038984539	phosphoribosyl-ATP pyrophosphatase [Myroides odoratimimus].	42.50	120	59	2	18	127	5	124	5e-26	107
rs:WP_014438364	phosphoribosyl-AMP cyclohydrolase [Phycisphaera mikurensis].	45.76	118	54	1	17	124	26	143	5e-26	106
rs:WP_035566286	phosphoribosyl-ATP pyrophosphatase [Hymenobacter sp. IS2118].	43.75	112	57	1	1	112	1	106	5e-26	108
rs:WP_044090989	phosphoribosyl-AMP cyclohydrolase, partial [Mycobacterium avium].	51.58	95	46	0	18	112	11	105	5e-26	105
rs:WP_031881446	phosphoribosyl-ATP pyrophosphatase [Staphylococcus aureus].	48.39	93	48	0	24	116	11	103	5e-26	107
rs:WP_032554761	phosphoribosyl-ATP pyrophosphatase [Peptoclostridium difficile].	44.14	111	62	0	17	127	3	113	5e-26	107
rs:WP_003692638	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Lactobacillus].	47.96	98	51	0	20	117	5	102	5e-26	105
rs:WP_020977656	histidine biosynthesis bifunctional protein HisIE [Staphylococcus aureus].	48.39	93	48	0	24	116	11	103	5e-26	107
rs:WP_020004606	phosphoribosyl-ATP pyrophosphatase [Brachyspira innocens].	46.39	97	52	0	18	114	12	108	5e-26	108
rs:WP_040132943	phosphoribosyl-ATP pyrophosphatase [Providencia stuartii].	50.56	89	44	0	24	112	17	105	5e-26	107
rs:WP_016156897	histidine biosynthesis HisIE [Citrobacter sp. KTE32].	46.02	113	51	1	24	126	17	129	5e-26	107
rs:WP_017472093	hypothetical protein [Amphibacillus jilinensis].	47.57	103	54	0	24	126	8	110	5e-26	108
rs:WP_045755249	phosphoribosyl-ATP pyrophosphatase [Sphingobacterium sp. PM2-P1-29].	52.75	91	43	0	24	114	9	99	5e-26	107
rs:WP_016537206	phosphoribosyl-ATP diphosphatase [Cedecea davisae].	51.69	89	43	0	24	112	17	105	5e-26	107
tr:A0A0B3B116_9ARCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	53.19	94	44	0	24	117	10	103	5e-26	105
rs:WP_006683943	phosphoribosyl-AMP cyclohydrolase [Citrobacter youngae].	45.13	113	52	1	24	126	17	129	5e-26	107
rs:WP_038867126	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Vibrio].	51.69	89	43	0	24	112	22	110	5e-26	107
rs:WP_039975068	phosphoribosyl-ATP pyrophosphatase [Vibrio jasicida].	51.69	89	43	0	24	112	22	110	5e-26	107
rs:WP_032357261	hypothetical protein, partial [Shigella flexneri].	49.44	89	45	0	24	112	17	105	5e-26	105
rs:WP_014289623	phosphoribosyl-AMP cyclohydrolase [Pyrobaculum sp. 1860].	47.32	112	54	2	16	122	17	128	5e-26	105
rs:WP_031428653	phosphoribosyl-ATP pyrophosphatase [Leeuwenhoekiella sp. MAR_2009_132].	47.87	94	49	0	18	111	3	96	5e-26	107
tr:A0A077UMI5_STAAU	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	49.46	93	47	0	24	116	11	103	5e-26	107
rs:WP_021408065	phosphoribosyl-ATP diphosphatase [Peptoclostridium difficile].	44.14	111	62	0	17	127	19	129	5e-26	108
rs:WP_032334726	hypothetical protein, partial [Shigella flexneri].	49.44	89	45	0	24	112	17	105	5e-26	105
rs:WP_024281639	phosphoribosyl-ATP pyrophosphatase [Algoriphagus marincola].	50.00	96	47	1	17	111	2	97	5e-26	107
rs:WP_020247689	phosphoribosyl-AMP cyclohydrolase [Marine Group I thaumarchaeote SCGC AB-629-I23].	41.90	105	60	1	11	114	1	105	5e-26	105
rs:WP_042481952	phosphoribosyl-ATP pyrophosphatase [Vibrio diazotrophicus].	51.69	89	43	0	24	112	14	102	6e-26	107
rs:WP_043949345	phosphoribosyl-AMP cyclohydrolase [Candidatus Phaeomarinobacter ectocarpi].	49.51	103	50	1	19	119	25	127	6e-26	106
rs:WP_028289786	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Olleya].	47.25	91	48	0	21	111	8	98	6e-26	107
rs:WP_014231493	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Vibrio].	51.69	89	43	0	24	112	22	110	6e-26	107
rs:WP_045597766	phosphoribosyl-ATP pyrophosphatase [Vibrio vulnificus].	51.69	89	43	0	24	112	22	110	6e-26	107
rs:WP_001067500	histidine biosynthesis bifunctional protein HisIE [Vibrio cholerae].	51.69	89	43	0	24	112	21	109	6e-26	107
rs:WP_042069438	phosphoribosyl-ATP pyrophosphatase [Aeromonas enteropelogenes].	51.69	89	43	0	24	112	23	111	6e-26	107
rs:WP_011524481	phosphoribosyl-AMP cyclohydrolase [Candidatus Koribacter versatilis].	51.96	102	46	2	24	122	10	111	6e-26	105
rs:WP_029801018	phosphoribosyl-ATP pyrophosphatase, partial [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	6e-26	105
rs:WP_039749387	phosphoribosyl-ATP pyrophosphatase [Hassallia byssoidea].	50.00	102	45	2	11	112	4	99	6e-26	107
rs:WP_036091797	phosphoribosyl-AMP cyclohydrolase [Leuconostoc mesenteroides].	42.73	110	59	1	8	117	3	108	6e-26	105
sp:HIS2_VIBVY	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	51.69	89	43	0	24	112	22	110	6e-26	107
rs:WP_013871059	phosphoribosyl-AMP cyclohydrolase [Lacinutrix sp. 5H-3-7-4].	48.35	91	47	0	21	111	8	98	6e-26	107
rs:WP_045465242	phosphoribosyl-ATP pyrophosphatase [Vibrio sp. 100512A].	51.69	89	43	0	24	112	22	110	6e-26	107
rs:WP_019081014	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Yersinia].	48.42	95	49	0	24	118	17	111	6e-26	107
rs:WP_028841016	phosphoribosyl-AMP cyclohydrolase [Thermodesulfobacterium hveragerdense].	44.55	110	60	1	23	131	11	120	6e-26	105
rs:WP_020605819	phosphoribosyl-AMP cyclohydrolase [Spirosoma spitsbergense].	48.00	100	50	1	15	112	2	101	6e-26	107
rs:WP_003687623	phosphoribosyl-AMP cyclohydrolase [Lactobacillus mali].	44.44	99	55	0	24	122	9	107	6e-26	105
rs:WP_010646120	phosphoribosyl-AMP cyclohydrolase [Vibrio campbellii].	51.69	89	43	0	24	112	22	110	6e-26	107
rs:WP_039432431	phosphoribosyl-ATP pyrophosphatase [Vibrio navarrensis].	51.69	89	43	0	24	112	22	110	6e-26	107
rs:WP_040147814	phosphoribosyl-ATP pyrophosphatase [Klebsiella pneumoniae].	51.69	89	43	0	24	112	13	101	6e-26	107
rs:WP_011963101	phosphoribosyl-AMP cyclohydrolase [Flavobacterium psychrophilum].	49.45	91	46	0	21	111	8	98	6e-26	107
rs:WP_042739207	phosphoribosyl-ATP pyrophosphatase [Staphylococcus gallinarum].	46.00	100	54	0	24	123	9	108	6e-26	107
rs:WP_026899137	phosphoribosyl-ATP pyrophosphatase [Pedobacter oryzae].	46.46	99	52	1	17	114	2	100	6e-26	107
rs:WP_038503489	phosphoribosyl-ATP pyrophosphatase [Flavobacterium psychrophilum].	49.45	91	46	0	21	111	8	98	6e-26	107
rs:WP_034098228	phosphoribosyl-ATP pyrophosphatase [Flavobacterium psychrophilum].	49.45	91	46	0	21	111	8	98	6e-26	107
rs:WP_038050463	hypothetical protein [Thermoanaerobaculum aquaticum].	50.51	99	49	0	18	116	1	99	6e-26	107
rs:WP_047108332	phosphoribosyl-ATP pyrophosphatase [Brachyspira hyodysenteriae].	45.45	99	54	0	18	116	12	110	6e-26	107
rs:WP_019898675	phosphoribosyl-AMP cyclohydrolase [Lactobacillus paracasei].	47.96	98	51	0	24	121	11	108	6e-26	105
rs:WP_014789649	phosphoribosyl-ATP pyrophosphatase [Thermococcus sp. CL1].	53.33	90	41	1	24	113	15	103	6e-26	107
rs:WP_021838419	phosphoribosyl-AMP cyclohydrolase [Alistipes sp. CAG:514].	48.48	99	51	0	13	111	4	102	6e-26	107
rs:WP_014976952	phosphoribosyl-AMP cyclohydrolase [Alteromonas macleodii].	51.11	90	44	0	24	113	18	107	6e-26	107
rs:WP_026743462	phosphoribosyl-ATP pyrophosphatase [Lonsdalea quercina].	51.69	89	43	0	24	112	17	105	6e-26	107
tr:B3T2E2_9ZZZZ	SubName: Full=Putative phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:ABZ06751.1};	46.60	103	54	1	19	120	23	125	6e-26	106
rs:WP_029920407	phosphoribosyl-AMP cyclohydrolase [Nevskia soli].	51.46	103	49	1	19	120	29	131	6e-26	106
rs:WP_028783702	phosphoribosyl-ATP pyrophosphatase [Thalassobacillus devorans].	46.32	95	51	0	18	112	6	100	6e-26	107
rs:WP_014979742	phosphoribosyl-AMP cyclohydrolase [Alteromonas macleodii].	51.11	90	44	0	24	113	18	107	6e-26	107
rs:WP_034369563	phosphoribosyl-ATP diphosphatase [Helicobacter sp. MIT 05-5293].	50.00	90	45	0	24	113	14	103	7e-26	108
rs:WP_040981571	phosphoribosyl-AMP cyclohydrolase [Mesorhizobium plurifarium].	53.21	109	49	1	19	125	25	133	7e-26	106
rs:WP_009124179	phosphoribosyl-AMP cyclohydrolase [Bacteroides fluxus].	47.06	102	48	2	11	112	3	98	7e-26	107
rs:WP_039429664	phosphoribosyl-ATP pyrophosphatase [Vibrio navarrensis].	51.69	89	43	0	24	112	22	110	7e-26	107
rs:WP_004289962	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacteroides].	47.06	102	48	2	11	112	2	97	7e-26	107
rs:WP_014998872	phosphoribosyl-AMP cyclohydrolase [Alteromonas macleodii].	51.11	90	44	0	24	113	18	107	7e-26	107
rs:WP_012671614	phosphoribosyl-ATP pyrophosphatase [Brachyspira hyodysenteriae].	45.45	99	54	0	18	116	12	110	7e-26	107
rs:WP_033099836	phosphoribosyl-ATP pyrophosphatase [Thermoactinomyces daqus].	43.36	113	64	0	13	125	5	117	7e-26	107
rs:WP_039225197	phosphoribosyl-ATP pyrophosphatase [Alteromonas macleodii].	51.11	90	44	0	24	113	18	107	7e-26	107
rs:WP_014950034	phosphoribosyl-AMP cyclohydrolase [Alteromonas macleodii].	51.11	90	44	0	24	113	18	107	7e-26	107
rs:WP_036912705	phosphoribosyl-ATP pyrophosphatase [Prevotella sp. FD3004].	52.22	90	43	0	23	112	9	98	7e-26	107
rs:WP_022923890	phosphoribosyl-AMP cyclohydrolase [Serinicoccus marinus].	46.23	106	56	1	8	112	10	115	7e-26	107
rs:WP_032429637	phosphoribosyl-ATP pyrophosphatase [Klebsiella pneumoniae].	51.69	89	43	0	24	112	13	101	7e-26	107
rs:WP_002815284	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Leuconostoc].	42.73	110	59	1	8	117	3	108	7e-26	105
gpu:CP011097_1405	hypothetical protein [Thaumarchaeota archaeon SAT1]	48.35	91	47	0	24	114	15	105	7e-26	104
rs:WP_032816139	phosphoribosyl-ATP pyrophosphatase [Yersinia rohdei].	48.42	95	49	0	24	118	17	111	7e-26	107
rs:WP_025586368	phosphoribosyl-ATP pyrophosphatase, partial [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	7e-26	105
rs:WP_017637663	MULTISPECIES: hypothetical protein [Staphylococcus].	46.00	100	53	1	15	114	2	100	7e-26	107
rs:WP_015067587	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Alteromonas].	51.11	90	44	0	24	113	18	107	7e-26	107
sp:HIS3_IGNH4	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.51	99	48	1	26	123	25	123	7e-26	105
rs:WP_017917693	phosphoribosyl-AMP cyclohydrolase [Xanthomonas sp. SHU308].	51.69	89	43	0	24	112	23	111	7e-26	107
rs:WP_042278796	phosphoribosyl-ATP pyrophosphatase [Nonlabens sediminis].	46.94	98	50	1	17	112	3	100	7e-26	107
rs:WP_046466568	phosphoribosyl-ATP pyrophosphatase [Staphylococcus pasteuri].	46.00	100	53	1	15	114	2	100	7e-26	107
rs:WP_028726160	phosphoribosyl-ATP pyrophosphatase [Parabacteroides gordonii].	47.78	90	47	0	23	112	9	98	7e-26	107
rs:WP_036821010	phosphoribosyl-ATP pyrophosphatase [Polaribacter sp. Hel1_85].	48.35	91	47	0	21	111	8	98	7e-26	107
rs:WP_018668552	phosphoribosyl-AMP cyclohydrolase [Bacteroides gallinarum].	47.06	102	48	2	11	112	2	97	7e-26	107
tr:A0A095ER58_BURCE	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	44.25	113	61	1	5	117	2	112	7e-26	108
rs:WP_013926591	phosphoribosyl-AMP cyclohydrolase [Runella slithyformis].	47.78	90	47	0	24	113	11	100	7e-26	107
rs:WP_009121598	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacteroides].	47.06	102	48	2	11	112	2	97	7e-26	107
rs:WP_031341478	phosphoribosyl-AMP cyclohydrolase [Novosphingobium lindaniclasticum].	49.47	95	48	0	19	113	18	112	7e-26	105
tr:R4M6X2_MYCTX	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	46.49	114	55	1	18	125	11	124	7e-26	106
rs:WP_009133172	phosphoribosyl-AMP cyclohydrolase [Alistipes indistinctus].	48.91	92	47	0	21	112	12	103	7e-26	107
rs:WP_022104542	phosphoribosyl-ATP diphosphatase [Bacteroides stercoris CAG:120].	47.06	102	48	2	11	112	2	97	7e-26	107
rs:WP_024273560	phosphoribosyl-ATP pyrophosphatase [Staphylococcus aureus].	48.39	93	48	0	24	116	11	103	7e-26	107
rs:WP_032519192	phosphoribosyl-ATP pyrophosphatase [Peptoclostridium difficile].	43.24	111	63	0	17	127	3	113	7e-26	107
rs:WP_023655467	phosphoribosyl-AMP cyclohydrolase [Erwinia piriflorinigrans].	49.47	95	48	0	24	118	17	111	7e-26	107
rs:WP_027723883	imidazole glycerol phosphate synthase [Tuberibacillus calidus].	46.73	107	51	1	24	130	8	108	8e-26	107
rs:WP_029739243	phosphoribosyl-ATP pyrophosphatase [Enterobacter asburiae].	44.25	113	53	1	24	126	17	129	8e-26	107
rs:WP_010016959	phosphoribosyl-AMP cyclohydrolase [Leuconostoc gelidum].	45.71	105	54	1	17	118	6	110	8e-26	105
rs:WP_026683102	phosphoribosyl-ATP pyrophosphatase [Bacillus megaterium].	42.72	103	59	0	11	113	1	103	8e-26	107
rs:WP_029799572	phosphoribosyl-ATP pyrophosphatase, partial [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	8e-26	105
rs:WP_040575070	phosphoribosyl-ATP pyrophosphatase [Pontibacter sp. BAB1700].	46.08	102	49	1	11	112	3	98	8e-26	107
rs:WP_029891087	phosphoribosyl-AMP cyclohydrolase [Polycyclovorans algicola].	50.00	102	50	1	19	119	25	126	8e-26	105
rs:WP_038452985	phosphoribosyl-ATP diphosphatase [Campylobacter iguaniorum].	47.87	94	48	1	24	116	10	103	8e-26	108
rs:WP_006115573	phosphoribosyl-AMP cyclohydrolase [Acetobacter pomorum].	46.73	107	55	1	19	123	31	137	8e-26	106
rs:WP_005652632	phosphoribosyl-AMP cyclohydrolase [Bacteroides stercoris].	47.06	102	48	2	11	112	2	97	8e-26	107
rs:WP_017458458	phosphoribosyl-AMP cyclohydrolase [Kosakonia sacchari].	50.56	89	44	0	24	112	17	105	8e-26	107
tr:T0JAE3_9SPHN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	49.47	95	48	0	19	113	20	114	8e-26	105
rs:WP_027878984	phosphoribosyl-ATP pyrophosphatase [Mesoflavibacter zeaxanthinifaciens].	49.45	91	46	0	21	111	8	98	8e-26	107
rs:WP_031842414	phosphoribosyl-ATP pyrophosphatase, partial [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	8e-26	105
rs:WP_038055101	phosphoribosyl-AMP cyclohydrolase [Thermodesulfobacterium hydrogeniphilum].	42.06	107	62	0	24	130	11	117	8e-26	105
tr:J0L8V4_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	46.08	102	49	1	11	112	6	101	8e-26	107
rs:WP_020363251	phosphoribosyl-AMP cyclohydrolase [Staphylococcus epidermidis].	50.56	89	44	0	24	112	10	98	8e-26	107
tr:Z2EW96_VIBPH	SubName: Full=Phosphoribosyl-AMP cyclohydrolase family protein {ECO:0000313|EMBL:EVU20077.1}; Flags: Fragment;	50.56	89	44	0	24	112	22	110	8e-26	105
gpu:CP009501_1231	Phosphoribosyl-AMP cyclohydrolase [Methanosarcina thermophila TM-1]	62.16	74	28	0	40	113	1	74	8e-26	103
rs:WP_019733570	phosphoribosyl-AMP cyclohydrolase [Mycobacterium avium].	51.58	95	46	0	18	112	11	105	8e-26	104
rs:WP_045510653	phosphoribosyl-ATP pyrophosphatase [Kosakonia oryzae].	50.56	89	44	0	24	112	17	105	8e-26	107
rs:WP_013622512	phosphoribosyl-AMP cyclohydrolase [Cellulophaga lytica].	47.52	101	48	1	11	111	3	98	8e-26	107
rs:WP_009800741	phosphoribosyl-AMP cyclohydrolase [Oceanicaulis sp. HTCC2633].	52.22	90	43	0	23	112	11	100	8e-26	107
rs:WP_042026293	phosphoribosyl-ATP pyrophosphatase [Aeromonas enteropelogenes].	52.81	89	42	0	24	112	23	111	8e-26	107
rs:WP_038641733	phosphoribosyl-ATP pyrophosphatase [Citrobacter freundii].	45.13	113	52	1	24	126	17	129	9e-26	107
rs:WP_034643460	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Cellulophaga].	47.52	101	48	1	11	111	3	98	9e-26	107
rs:WP_043091912	phosphoribosyl-ATP pyrophosphatase [Xanthomonas sacchari].	51.69	89	43	0	24	112	23	111	9e-26	107
rs:WP_021947137	phosphoribosyl-ATP diphosphatase [Prevotella sp. CAG:1124].	50.00	90	45	0	23	112	9	98	9e-26	107
rs:WP_015361241	histidine biosynthesis protein HisIE [Nonlabens dokdonensis].	45.79	107	52	2	17	121	2	104	9e-26	107
rs:WP_035352217	phosphoribosyl-AMP cyclohydrolase [Acetobacter pomorum].	46.73	107	55	1	19	123	31	137	9e-26	106
rs:WP_007551402	phosphoribosyl-AMP cyclohydrolase [Candidatus Nitrosoarchaeum koreensis].	42.74	117	59	2	1	117	1	109	9e-26	104
rs:WP_041877804	phosphoribosyl-ATP pyrophosphatase [Pedobacter sp. NL19].	51.65	91	44	0	24	114	10	100	9e-26	107
rs:WP_022019937	phosphoribosyl-ATP diphosphatase [Bacteroides sp. CAG:661].	46.08	102	49	1	11	112	8	103	9e-26	107
rs:WP_005168349	phosphoribosyl-AMP cyclohydrolase [Yersinia enterocolitica].	47.37	95	50	0	24	118	17	111	9e-26	107
rs:WP_008105826	phosphoribosyl-AMP cyclohydrolase [Methylophilales bacterium HTCC2181].	42.57	101	57	1	17	116	7	107	9e-26	105
sp:HIS3_MYCMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.53	95	47	0	18	112	11	105	9e-26	104
tr:C8PI34_9PROT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	52.63	95	44	1	23	116	9	103	9e-26	109
rs:WP_019210520	phosphoribosyl-AMP cyclohydrolase [Yersinia massiliensis].	48.42	95	49	0	24	118	17	111	9e-26	107
rs:WP_007805050	phosphoribosyl-AMP cyclohydrolase [Rhodanobacter spathiphylli].	51.00	100	48	1	14	112	6	105	9e-26	107
rs:WP_047074832	phosphoribosyl-ATP pyrophosphatase [Enterobacter asburiae].	44.25	113	53	1	24	126	17	129	9e-26	107
rs:WP_035483007	phosphoribosyl-ATP pyrophosphatase [Algoriphagus marincola].	48.51	101	48	1	11	111	1	97	9e-26	107
rs:WP_038232715	phosphoribosyl-ATP pyrophosphatase [Zobellia uliginosa].	49.45	91	46	0	21	111	8	98	9e-26	107
rs:WP_038634266	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Yersinia].	48.42	95	49	0	24	118	17	111	9e-26	107
rs:WP_015572393	phosphoribosyl-AMP cyclohydrolase [Enterobacter cloacae].	49.44	89	45	0	24	112	17	105	9e-26	107
rs:WP_043865110	phosphoribosyl-ATP pyrophosphatase [Enterobacter aerogenes].	43.24	111	57	1	2	112	1	105	9e-26	107
rs:WP_008141735	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacteroides].	50.56	89	44	0	24	112	10	98	9e-26	107
rs:WP_031589132	phosphoribosyl-ATP pyrophosphatase [Klebsiella pneumoniae].	51.69	89	43	0	24	112	13	101	9e-26	107
rs:WP_025255779	phosphoribosyl-ATP pyrophosphatase [Alteromonas sp. ALT199].	51.11	90	44	0	24	113	18	107	9e-26	107
rs:WP_035453028	hypothetical protein [Alicyclobacillus herbarius].	51.61	93	45	0	21	113	21	113	9e-26	109
rs:WP_021426302	phosphoribosyl-ATP diphosphatase [Peptoclostridium difficile].	43.24	111	63	0	17	127	19	129	1e-25	107
rs:WP_017034912	phosphoribosyl-AMP cyclohydrolase [Vibrio genomosp. F10].	50.56	89	44	0	24	112	22	110	1e-25	107
rs:WP_013114297	phosphoribosyl-ATP pyrophosphatase [Brachyspira murdochii].	46.39	97	52	0	18	114	12	108	1e-25	107
rs:WP_013365671	phosphoribosyl-AMP cyclohydrolase [Enterobacter lignolyticus].	51.69	89	43	0	24	112	13	101	1e-25	107
rs:WP_037357966	phosphoribosyl-ATP pyrophosphatase [Schleiferia thermophila].	51.69	89	43	0	24	112	11	99	1e-25	107
rs:WP_044327335	phosphoribosyl-ATP pyrophosphatase [Citrobacter amalonaticus].	46.02	113	51	1	24	126	17	129	1e-25	107
rs:WP_029147970	phosphoribosyl-AMP cyclohydrolase [Methylophilus sp. 5].	47.92	96	49	1	24	118	13	108	1e-25	105
tr:C2XRE7_BACCE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	51.69	89	43	0	25	113	1	89	1e-25	103
rs:WP_007428142	phosphoribosyl-ATP pyrophosphatase [Paenibacillus sp. Aloe-11].	48.45	97	50	0	17	113	17	113	1e-25	107
rs:WP_019466652	phosphoribosyl-AMP cyclohydrolase [Dyella japonica].	49.51	103	51	1	11	112	4	106	1e-25	107
rs:WP_046948633	phosphoribosyl-AMP cyclohydrolase [Lactobacillus fermentum].	52.13	94	45	0	24	117	8	101	1e-25	104
rs:WP_025505241	phosphoribosyl-ATP pyrophosphatase, partial [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	2	90	1e-25	106
rs:WP_002487484	phosphoribosyl-AMP cyclohydrolase [Staphylococcus epidermidis].	50.56	89	44	0	24	112	10	98	1e-25	107
rs:WP_021711048	histidine biosynthesis bifunctional protein HisIE [Vibrio azureus].	50.00	90	45	0	23	112	21	110	1e-25	107
rs:WP_039128556	phosphoribosyl-ATP pyrophosphatase [Flavihumibacter sp. ZG627].	48.94	94	47	1	18	111	6	98	1e-25	106
rs:WP_042389893	phosphoribosyl-ATP pyrophosphatase [Escherichia vulneris].	51.69	89	43	0	24	112	17	105	1e-25	107
rs:WP_002496014	phosphoribosyl-AMP cyclohydrolase [Staphylococcus epidermidis].	50.56	89	44	0	24	112	10	98	1e-25	107
rs:WP_041156592	phosphoribosyl-ATP pyrophosphatase [Vibrio mytili].	51.11	90	44	0	23	112	21	110	1e-25	107
rs:WP_022163050	phosphoribosyl-ATP diphosphatase [Bacteroides sp. CAG:633].	47.06	102	48	2	11	112	3	98	1e-25	107
rs:WP_002490178	phosphoribosyl-AMP cyclohydrolase [Staphylococcus epidermidis].	50.56	89	44	0	24	112	10	98	1e-25	107
rs:WP_037442132	phosphoribosyl-ATP pyrophosphatase [Sphingobacterium antarcticum].	50.00	92	46	0	23	114	9	100	1e-25	106
rs:WP_013975127	phosphoribosyl-AMP cyclohydrolase [Leuconostoc sp. C2].	50.00	92	46	0	25	116	17	108	1e-25	105
rs:WP_003876212	phosphoribosyl-AMP cyclohydrolase [Mycobacterium avium].	50.53	95	47	0	18	112	11	105	1e-25	104
rs:WP_007989704	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Glaciecola].	51.69	89	43	0	24	112	18	106	1e-25	107
rs:WP_000954862	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	49.44	89	45	0	24	112	17	105	1e-25	106
rs:WP_039439372	phosphoribosyl-ATP pyrophosphatase [Vibrio navarrensis].	51.69	89	43	0	24	112	22	110	1e-25	107
rs:WP_006991939	MULTISPECIES: histidine biosynthesis bifunctional protein hisIE [Alteromonadales].	50.56	89	44	0	24	112	18	106	1e-25	107
rs:WP_012519070	phosphoribosyl-AMP cyclohydrolase [Alteromonas macleodii].	51.11	90	44	0	24	113	18	107	1e-25	107
rs:WP_044258716	phosphoribosyl-ATP pyrophosphatase [Citrobacter sp. JT3].	46.02	113	51	1	24	126	17	129	1e-25	107
rs:WP_037531202	phosphoribosyl-AMP cyclohydrolase [Sphingomonas sp. RIT328].	48.11	106	53	2	19	123	14	118	1e-25	104
rs:WP_025612169	phosphoribosyl-ATP pyrophosphatase [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	1e-25	107
tr:A0A077VHC1_STAAU	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	48.39	93	48	0	24	116	11	103	1e-25	107
rs:WP_013622941	phosphoribosyl-AMP cyclohydrolase [Deinococcus proteolyticus].	49.50	101	50	1	13	112	12	112	1e-25	107
rs:WP_032911584	phosphoribosyl-ATP pyrophosphatase [Yersinia frederiksenii].	48.94	94	48	0	25	118	18	111	1e-25	107
rs:WP_041140656	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Epsilonproteobacteria].	52.22	90	43	0	25	114	15	104	1e-25	107
rs:WP_017693103	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Enterobacteriaceae].	48.31	89	46	0	24	112	17	105	1e-25	106
tr:A0A087S4I4_9ARCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	38.53	109	66	1	11	118	1	109	1e-25	104
rs:WP_047055209	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	48.31	89	46	0	24	112	17	105	1e-25	106
rs:WP_009381812	phosphoribosyl-AMP cyclohydrolase [Staphylococcus massiliensis].	51.61	93	45	0	24	116	10	102	1e-25	107
rs:WP_026902471	phosphoribosyl-ATP pyrophosphatase [Pedobacter glucosidilyticus].	47.25	91	48	0	24	114	10	100	1e-25	106
rs:WP_018746614	hypothetical protein [Chitiniphilus shinanonensis].	47.52	101	52	1	18	117	8	108	1e-25	104
gp:CP006656_1678	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein [Klebsiella pneumoniae JM45]	51.69	89	43	0	24	112	13	101	1e-25	106
rs:WP_039133935	phosphoribosyl-ATP pyrophosphatase [Gallibacterium genomosp. 2].	49.45	91	46	0	23	113	16	106	1e-25	107
rs:WP_039030242	phosphoribosyl-ATP pyrophosphatase [Leclercia adecarboxylata].	45.13	113	52	1	24	126	17	129	1e-25	106
rs:WP_015431925	histidine biosynthesis bifunctional protein HisIE [Bibersteinia trehalosi].	46.00	100	54	0	24	123	12	111	1e-25	107
rs:WP_017913328	phosphoribosyl-AMP cyclohydrolase [Xanthomonas sp. SHU166].	51.69	89	43	0	24	112	23	111	1e-25	107
rs:WP_001633115	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	50.56	89	44	0	24	112	17	105	1e-25	106
tr:A0A077TYU3_STAAU	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	48.39	93	48	0	24	116	11	103	1e-25	107
gp:CP003233_1514	imidazole glycerol phosphate synthase subunit HisF [Mycobacterium tuberculosis RGTB327]	51.58	95	46	0	18	112	278	372	1e-25	109
rs:WP_014544590	phosphoribosyl-AMP cyclohydrolase [Erwinia sp. Ejp617].	49.47	95	48	0	24	118	17	111	1e-25	106
rs:WP_027952639	phosphoribosyl-ATP pyrophosphatase [Hallella seregens].	51.69	89	43	0	24	112	10	98	1e-25	107
tr:A0A077VTI3_STAAU	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	48.39	93	48	0	24	116	11	103	1e-25	107
rs:WP_004184787	phosphoribosyl-AMP cyclohydrolase [Klebsiella pneumoniae].	51.69	89	43	0	24	112	13	101	1e-25	106
rs:WP_039448533	phosphoribosyl-ATP pyrophosphatase [Pedobacter glucosidilyticus].	47.25	91	48	0	24	114	10	100	1e-25	106
gp:X03975_1	Salmonella typhimurium hisIE gene. [Salmonella enterica subsp. enterica serovar Typhimurium]	46.90	113	50	1	24	126	17	129	1e-25	106
rs:WP_045330398	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	49.44	89	45	0	24	112	17	105	1e-25	106
rs:WP_043799757	phosphoribosyl-ATP pyrophosphatase [Arenimonas malthae].	53.26	92	43	0	21	112	13	104	1e-25	106
rs:WP_033812611	hypothetical protein, partial [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-25	103
rs:WP_008237305	phosphoribosyl-AMP cyclohydrolase [Pedobacter sp. BAL39].	51.65	91	44	0	24	114	10	100	1e-25	106
rs:WP_014034421	phosphoribosyl-AMP cyclohydrolase [Muricauda ruestringensis].	50.55	91	45	0	21	111	8	98	1e-25	106
tr:W1A3F5_KLEPN	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	51.69	89	43	0	24	112	12	100	1e-25	106
rs:WP_004175270	phosphoribosyl-AMP cyclohydrolase [Klebsiella pneumoniae].	51.69	89	43	0	24	112	13	101	1e-25	106
rs:WP_035685452	phosphoribosyl-ATP pyrophosphatase [Avibacterium paragallinarum].	50.00	90	45	0	24	113	12	101	1e-25	106
tr:Q1PZK9_9BACT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	45.83	96	52	0	18	113	7	102	1e-25	104
rs:WP_023159144	phosphoribosyl-ATP diphosphatase [Klebsiella pneumoniae].	51.69	89	43	0	24	112	13	101	1e-25	106
rs:WP_045908603	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	44.25	113	53	1	24	126	17	129	1e-25	106
rs:WP_044868269	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	44.25	113	53	1	24	126	17	129	1e-25	106
rs:WP_011899681	phosphoribosyl-AMP cyclohydrolase [Pyrobaculum arsenaticum].	53.93	89	41	0	24	112	37	125	1e-25	105
rs:WP_014170795	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Enterobacter cloacae complex].	44.25	113	53	1	24	126	17	129	1e-25	106
rs:WP_034523958	phosphoribosyl-ATP pyrophosphatase [Bacteroides stercorirosoris].	47.06	102	48	2	11	112	1	96	1e-25	106
rs:WP_000170493	phosphoribosyl-AMP cyclohydrolase [Staphylococcus aureus].	48.39	93	48	0	24	116	11	103	1e-25	106
rs:WP_031787607	phosphoribosyl-ATP pyrophosphatase [Staphylococcus aureus].	48.39	93	48	0	24	116	11	103	1e-25	106
rs:WP_010178470	phosphoribosyl-AMP cyclohydrolase [Glaciecola sp. HTCC2999].	51.11	90	44	0	24	113	18	107	1e-25	106
rs:WP_028013768	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	44.25	113	53	1	24	126	17	129	1e-25	106
rs:WP_024908078	phosphoribosyl-ATP pyrophosphatase [Enterobacter asburiae].	44.25	113	53	1	24	126	17	129	1e-25	106
rs:WP_016189817	histidine biosynthesis bifunctional protein [Erwinia tracheiphila].	47.37	95	50	0	24	118	17	111	1e-25	106
tr:W0QR85_9PAST	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	45.00	100	55	0	24	123	13	112	1e-25	106
rs:WP_026809743	phosphoribosyl-ATP pyrophosphatase [Arenibacter latericius].	49.45	91	46	0	21	111	8	98	1e-25	106
rs:WP_004200374	phosphoribosyl-AMP cyclohydrolase [Klebsiella pneumoniae].	51.69	89	43	0	24	112	13	101	1e-25	106
rs:WP_027391189	phosphoribosyl-ATP pyrophosphatase [Aquimarina latercula].	48.35	91	47	0	21	111	8	98	1e-25	106
tr:X1NLH9_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S03869 {ECO:0000313|EMBL:GAI19529.1}; Flags: Fragment;	44.55	101	50	1	11	111	3	97	1e-25	105
rs:WP_031879063	phosphoribosyl-ATP pyrophosphatase [Staphylococcus aureus].	48.39	93	48	0	24	116	11	103	1e-25	106
rs:WP_032440168	phosphoribosyl-ATP pyrophosphatase [Klebsiella pneumoniae].	51.69	89	43	0	24	112	13	101	1e-25	106
rs:WP_019149393	phosphoribosyl-AMP cyclohydrolase [Alistipes senegalensis].	51.69	89	43	0	24	112	19	107	1e-25	106
rs:WP_032435957	phosphoribosyl-ATP pyrophosphatase [Klebsiella pneumoniae].	51.69	89	43	0	24	112	13	101	1e-25	106
rs:WP_040174749	phosphoribosyl-ATP pyrophosphatase [Klebsiella pneumoniae].	51.69	89	43	0	24	112	13	101	1e-25	106
rs:WP_025759316	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	44.25	113	53	1	24	126	17	129	1e-25	106
rs:WP_019038674	phosphoribosyl-AMP cyclohydrolase [Psychroflexus tropicus].	48.35	91	47	0	21	111	8	98	1e-25	106
rs:WP_038398874	phosphoribosyl-ATP pyrophosphatase [Staphylococcus epidermidis].	49.44	89	45	0	24	112	10	98	1e-25	106
rs:WP_023579760	phosphoribosyl-ATP pyrophosphohydrolase [Flavobacterium limnosediminis].	49.45	91	46	0	21	111	8	98	1e-25	106
rs:WP_043016853	phosphoribosyl-ATP pyrophosphatase [Citrobacter freundii].	46.02	113	51	1	24	126	17	129	1e-25	106
tr:D6U5W8_9CHLR	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:EFH80379.1}; EC=3.5.4.19 {ECO:0000313|EMBL:EFH80379.1};	43.64	110	61	1	17	125	5	114	1e-25	108
tr:A0A099VYW2_9HELI	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	48.39	93	48	0	24	116	15	107	1e-25	107
rs:WP_002949285	nickel transporter [Campylobacter showae].	46.53	101	52	2	23	121	9	109	1e-25	108
rs:WP_006832063	phosphoribosyl-AMP cyclohydrolase [Erythrobacter sp. SD-21].	43.59	117	58	1	11	119	1	117	1e-25	104
rs:WP_032225605	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	49.44	89	45	0	24	112	17	105	1e-25	106
tr:A0A0B8QA07_9VIBR	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	51.14	88	43	0	25	112	1	88	1e-25	106
rs:WP_038643744	phosphoribosyl-ATP pyrophosphatase [Mannheimia varigena].	45.00	100	55	0	24	123	11	110	1e-25	106
rs:WP_029686656	phosphoribosyl-ATP pyrophosphatase [Tatumella saanichensis].	50.56	89	44	0	24	112	17	105	1e-25	106
rs:WP_028994442	phosphoribosyl-AMP cyclohydrolase [Azonexus hydrophilus].	48.11	106	52	3	10	114	7	110	1e-25	104
rs:WP_038162957	phosphoribosyl-ATP pyrophosphatase [Trabulsiella guamensis].	46.90	113	50	1	24	126	13	125	1e-25	106
rs:WP_024108722	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Dickeya].	50.00	90	45	0	24	113	17	106	1e-25	106
rs:WP_032434994	phosphoribosyl-ATP pyrophosphatase [Klebsiella pneumoniae].	51.69	89	43	0	24	112	13	101	1e-25	106
rs:WP_038060890	phosphoribosyl-AMP cyclohydrolase [Thermodesulfobacterium commune].	47.25	91	48	0	23	113	11	101	2e-25	104
rs:WP_045586551	phosphoribosyl-ATP pyrophosphatase [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_045286287	phosphoribosyl-ATP pyrophosphatase [Enterobacter sp. 35699].	44.25	113	53	1	24	126	17	129	2e-25	106
rs:WP_013103767	phosphoribosyl-AMP cyclohydrolase [Leuconostoc kimchii].	50.00	92	46	0	25	116	17	108	2e-25	104
rs:WP_029835470	phosphoribosyl-ATP pyrophosphatase [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_011575653	phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas atlantica].	50.56	89	44	0	24	112	18	106	2e-25	106
rs:WP_007103459	histidine biosynthesis bifunctional protein hisIE [Glaciecola polaris].	50.56	89	44	0	24	112	18	106	2e-25	106
rs:WP_005764939	phosphoribosyl-AMP cyclohydrolase [Pasteurella dagmatis].	50.00	90	45	0	24	113	14	103	2e-25	106
rs:WP_046005237	phosphoribosyl-ATP pyrophosphatase [Pseudoalteromonas rubra].	47.47	99	52	0	14	112	7	105	2e-25	106
rs:WP_002439969	phosphoribosyl-AMP cyclohydrolase [Shimwellia blattae].	50.56	89	44	0	24	112	17	105	2e-25	106
rs:WP_023479142	phosphoribosyl-ATP diphosphatase [Enterobacter cloacae].	49.44	89	45	0	24	112	17	105	2e-25	106
rs:WP_039888675	nickel transporter, partial [Campylobacter rectus].	46.53	101	52	2	23	121	9	109	2e-25	105
rs:WP_020903969	phosphoribosyl-AMP cyclohydrolase [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_017041608	phosphoribosyl-AMP cyclohydrolase [Vibrio genomosp. F10].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_007186786	phosphoribosyl-AMP cyclohydrolase [Hydrocarboniphaga effusa].	51.52	99	47	1	19	116	27	125	2e-25	105
rs:WP_013632768	phosphoribosyl-AMP cyclohydrolase [Pedobacter saltans].	47.92	96	49	1	20	114	9	104	2e-25	106
rs:WP_009075499	phosphoribosyl-AMP cyclohydrolase [Metallosphaera yellowstonensis].	46.15	104	55	1	16	118	11	114	2e-25	104
rs:WP_000954913	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Escherichia].	49.44	89	45	0	24	112	17	105	2e-25	106
sp:HIS2_SHIFL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	49.44	89	45	0	24	112	17	105	2e-25	106
rs:WP_025571418	phosphoribosyl-ATP pyrophosphatase [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_025605175	phosphoribosyl-ATP pyrophosphatase [Pontibacter actiniarum].	48.96	96	48	1	18	112	3	98	2e-25	106
tr:C4U4G7_YERAL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	48.39	93	48	0	26	118	1	93	2e-25	105
rs:WP_003467804	phosphoribosyl-AMP cyclohydrolase [Gracilibacillus halophilus].	48.48	99	51	0	24	122	8	106	2e-25	106
rs:WP_009793059	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Bacillus].	51.58	95	46	0	18	112	6	100	2e-25	106
rs:WP_038901081	phosphoribosyl-ATP pyrophosphatase [Dickeya dadantii].	48.89	90	46	0	24	113	17	106	2e-25	106
rs:WP_036580505	phosphoribosyl-ATP pyrophosphatase [Nonlabens ulvanivorans].	48.35	91	47	0	22	112	9	99	2e-25	106
rs:WP_020947305	hypothetical protein [Klebsiella pneumoniae].	51.69	89	43	0	24	112	12	100	2e-25	106
rs:WP_035894871	phosphoribosyl-ATP pyrophosphatase [Kluyvera ascorbata].	45.13	113	52	1	24	126	13	125	2e-25	106
rs:WP_021526182	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	2e-25	106
rs:WP_038643350	phosphoribosyl-ATP pyrophosphatase [Mannheimia varigena].	45.00	100	55	0	24	123	11	110	2e-25	106
tr:I8WAP8_9BACE	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	49.44	89	45	0	24	112	3	91	2e-25	106
rs:WP_032439380	phosphoribosyl-ATP pyrophosphatase [Klebsiella pneumoniae].	51.69	89	43	0	24	112	13	101	2e-25	106
rs:WP_004144136	phosphoribosyl-AMP cyclohydrolase [Klebsiella pneumoniae].	51.69	89	43	0	24	112	13	101	2e-25	106
rs:WP_002494590	phosphoribosyl-AMP cyclohydrolase [Staphylococcus epidermidis].	46.81	94	50	0	24	117	10	103	2e-25	106
rs:WP_032636074	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	43.36	113	54	1	24	126	17	129	2e-25	106
rs:WP_023282818	histidine biosynthesis HisIE [Klebsiella pneumoniae].	51.69	89	43	0	24	112	13	101	2e-25	106
tr:I6H228_SHIFL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	45.05	111	51	1	26	126	1	111	2e-25	105
rs:WP_029857403	phosphoribosyl-ATP pyrophosphatase [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_021453343	phosphoribosyl-ATP diphosphatase [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_046339587	phosphoribosyl-ATP pyrophosphatase [Pasteurella multocida].	50.00	90	45	0	24	113	14	103	2e-25	106
rs:WP_023294995	histidine biosynthesis HisIE [Enterobacter cloacae].	48.31	89	46	0	24	112	17	105	2e-25	106
rs:WP_014269959	phosphoribosyl-AMP cyclohydrolase [Sphaerochaeta pleomorpha].	52.04	98	46	1	24	121	10	106	2e-25	106
rs:WP_025818153	histidine biosynthesis bifunctional protein HisIE [Vibrio parahaemolyticus].	46.08	102	55	0	24	125	22	123	2e-25	106
sp:HIS3_MYCUA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.53	95	47	0	18	112	11	105	2e-25	103
rs:WP_015813685	phosphoribosyl-AMP cyclohydrolase [Dyadobacter fermentans].	47.47	99	50	1	16	112	6	104	2e-25	106
rs:WP_045727356	phosphoribosyl-ATP pyrophosphatase [Xanthomonas sp. GPE 39].	46.02	113	59	2	1	112	1	112	2e-25	106
rs:WP_045099514	phosphoribosyl-ATP pyrophosphatase [Tatlockia micdadei].	53.93	89	41	0	24	112	16	104	2e-25	106
tr:W0Q8D5_9PAST	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	45.00	100	55	0	24	123	13	112	2e-25	106
rs:WP_035427349	hypothetical protein [Lactobacillus fermentum].	54.95	91	41	0	24	114	8	98	2e-25	106
rs:WP_025536775	phosphoribosyl-ATP pyrophosphatase [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_025522839	phosphoribosyl-ATP pyrophosphatase [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_020063039	phosphoribosyl-AMP cyclohydrolase [Bacillus sp. 123MFChir2].	46.24	93	50	0	24	116	8	100	2e-25	103
rs:WP_044782692	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	49.44	89	45	0	24	112	17	105	2e-25	106
rs:WP_036213685	phosphoribosyl-ATP pyrophosphatase, partial [Lysobacter arseniciresistens].	47.27	110	57	1	10	118	4	113	2e-25	106
rs:WP_009484566	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Klebsiella].	51.69	89	43	0	24	112	13	101	2e-25	106
rs:WP_029844664	phosphoribosyl-ATP pyrophosphatase [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_029834382	phosphoribosyl-ATP pyrophosphatase [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_038911117	phosphoribosyl-ATP pyrophosphatase [Dickeya dadantii].	48.89	90	46	0	24	113	17	106	2e-25	106
rs:WP_043027892	phosphoribosyl-ATP pyrophosphatase [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_029802244	histidine biosynthesis bifunctional protein HisIE [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_004725396	phosphoribosyl-AMP cyclohydrolase [Vibrio furnissii].	50.56	89	44	0	24	112	20	108	2e-25	106
rs:WP_010413596	phosphoribosyl-AMP cyclohydrolase [Citromicrobium sp. JLT1363].	47.66	107	54	2	19	123	15	121	2e-25	103
tr:S8GR10_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	47.52	101	52	1	13	112	1	101	2e-25	106
rs:WP_029807088	phosphoribosyl-ATP pyrophosphatase [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_005489040	phosphoribosyl-AMP cyclohydrolase [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_041487083	phosphoribosyl-AMP cyclohydrolase [[Clostridium] sticklandii].	46.24	93	50	0	24	116	7	99	2e-25	103
rs:WP_027663035	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.89	90	46	0	23	112	16	105	2e-25	106
rs:WP_031820580	phosphoribosyl-ATP pyrophosphatase [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	12	100	2e-25	106
rs:WP_042770878	histidine biosynthesis bifunctional protein HisIE [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_025638430	histidine biosynthesis bifunctional protein HisIE [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:YP_002048684	histidine biosynthesis bifunctional protein HisIE [Paulinella chromatophora].	50.50	101	49	1	13	112	30	130	2e-25	107
sp:HIS2_VIBPA	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_000954795	phosphoribosyl-AMP cyclohydrolase [Escherichia fergusonii].	49.44	89	45	0	24	112	17	105	2e-25	106
tr:W8UH51_YEREN	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	47.37	95	50	0	24	118	17	111	2e-25	106
rs:WP_026465727	phosphoribosyl-ATP pyrophosphatase [Aerococcus urinaeequi].	46.15	104	50	1	9	112	2	99	2e-25	106
rs:WP_002862248	phosphoribosyl-AMP cyclohydrolase [Campylobacter jejuni].	45.26	95	52	0	25	119	19	113	2e-25	106
rs:WP_024105714	phosphoribosyl-AMP cyclohydrolase [Dickeya dianthicola].	48.89	90	46	0	24	113	17	106	2e-25	106
rs:WP_042780960	histidine biosynthesis bifunctional protein HisIE [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_029862840	phosphoribosyl-ATP pyrophosphatase [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_027304706	phosphoribosyl-ATP pyrophosphatase [Campylobacter upsaliensis].	43.30	97	55	0	23	119	17	113	2e-25	106
rs:WP_042425048	phosphoribosyl-ATP pyrophosphatase [Geomicrobium sp. JCM 19039].	49.47	95	48	0	18	112	6	100	2e-25	106
rs:WP_047123458	phosphoribosyl-ATP pyrophosphatase [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_022633359	histidine biosynthesis bifunctional protein hisIE [Dickeya solani].	48.89	90	46	0	24	113	17	106	2e-25	106
rs:WP_017054707	phosphoribosyl-AMP cyclohydrolase [Vibrio genomosp. F6].	50.00	90	45	0	23	112	27	116	2e-25	106
rs:WP_019978018	MULTISPECIES: hypothetical protein [unclassified Verrucomicrobia (miscellaneous)].	43.44	122	59	2	19	130	29	150	2e-25	105
rs:WP_011585709	phosphoribosyl-AMP cyclohydrolase [Cytophaga hutchinsonii].	48.31	89	46	0	23	111	9	97	2e-25	105
rs:WP_000954916	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	49.44	89	45	0	24	112	17	105	2e-25	106
rs:WP_034636487	phosphoribosyl-AMP cyclohydrolase [Bacillus manliponensis].	47.78	90	47	0	24	113	8	97	2e-25	103
rs:WP_032294817	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.89	90	46	0	23	112	16	105	2e-25	106
tr:A0A075HAT7_9ARCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	39.45	109	65	1	11	118	1	109	2e-25	103
rs:WP_025472027	phosphoribosyl-ATP pyrophosphatase, partial [Yersinia pestis].	50.00	88	44	0	25	112	18	105	2e-25	103
rs:WP_026715790	phosphoribosyl-ATP pyrophosphatase [Flavobacterium gelidilacus].	48.35	91	47	0	21	111	8	98	2e-25	105
rs:WP_035414061	phosphoribosyl-AMP cyclohydrolase [Exiguobacterium undae].	49.00	100	50	1	18	117	4	102	2e-25	103
rs:WP_021413885	phosphoribosyl-ATP diphosphatase [Peptoclostridium difficile].	43.24	111	63	0	17	127	19	129	2e-25	106
rs:WP_032552106	phosphoribosyl-ATP pyrophosphatase [Vibrio fortis].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_010559132	phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas spongiae].	46.46	99	53	0	14	112	7	105	2e-25	106
rs:WP_009495393	phosphoribosyl-AMP cyclohydrolase [Campylobacter showae].	48.91	92	46	1	23	113	9	100	2e-25	107
rs:WP_038436348	phosphoribosyl-ATP pyrophosphatase [endosymbiont of Llaveia axin axin].	46.60	103	50	1	9	111	2	99	2e-25	106
rs:WP_038918874	phosphoribosyl-ATP pyrophosphatase [Dickeya sp. MK7].	50.00	90	45	0	24	113	17	106	2e-25	106
rs:WP_038979599	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	43.36	113	54	1	24	126	17	129	2e-25	105
rs:WP_038695753	phosphoribosyl-ATP pyrophosphatase [Sphingobacterium sp. ML3W].	51.65	91	44	0	24	114	9	99	2e-25	105
rs:WP_020454278	phosphoribosyl-AMP cyclohydrolase [Enterobacter sp. R4-368].	49.44	89	45	0	24	112	17	105	2e-25	105
tr:A0A087RL76_9ARCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	41.90	105	60	1	11	114	1	105	2e-25	103
tr:K2EWL6_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	52.81	89	42	0	24	112	229	317	2e-25	108
rs:WP_042859675	phosphoribosyl-ATP pyrophosphatase [Dickeya sp. NCPPB 3274].	50.00	90	45	0	24	113	17	106	2e-25	105
rs:WP_043028124	phosphoribosyl-ATP pyrophosphatase [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	2e-25	106
rs:WP_000954837	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	49.44	89	45	0	24	112	17	105	2e-25	105
rs:WP_025829287	phosphoribosyl-AMP cyclohydrolase [Acetobacter persici].	51.49	101	47	1	19	117	31	131	2e-25	105
rs:WP_023303968	histidine biosynthesis HisIE [Enterobacter cloacae].	48.31	89	46	0	24	112	17	105	2e-25	105
rs:WP_014832598	phosphoribosyl-AMP cyclohydrolase [Enterobacter cloacae].	43.36	113	54	1	24	126	17	129	2e-25	105
tr:A0A068DS98_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	46.60	103	50	1	9	111	7	104	2e-25	106
rs:WP_045859517	phosphoribosyl-ATP pyrophosphatase [Raoultella terrigena].	49.44	89	45	0	24	112	13	101	2e-25	105
rs:WP_023284012	histidine biosynthesis HisIE [Klebsiella pneumoniae].	51.69	89	43	0	24	112	13	101	2e-25	105
rs:WP_033117225	phosphoribosyl-AMP cyclohydrolase [Intestinimonas butyriciproducens].	49.50	101	50	1	20	119	8	108	2e-25	103
rs:WP_012915773	phosphoribosyl-AMP cyclohydrolase [Xanthomonas albilineans].	46.02	113	59	2	1	112	1	112	2e-25	106
rs:WP_043760636	phosphoribosyl-ATP pyrophosphatase [Aeromonas taiwanensis].	51.69	89	43	0	24	112	23	111	2e-25	106
rs:WP_020732599	hypothetical protein [Sorangium cellulosum].	48.00	100	52	0	18	117	3	102	2e-25	106
rs:WP_042248057	phosphoribosyl-ATP pyrophosphatase [Nonlabens ulvanivorans].	48.35	91	47	0	22	112	9	99	2e-25	105
rs:WP_032103476	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae complex].	48.31	89	46	0	24	112	17	105	2e-25	105
rs:WP_003142166	phosphoribosyl-AMP cyclohydrolase [Aerococcus viridans].	51.69	89	43	0	24	112	11	99	2e-25	106
rs:WP_018933996	hypothetical protein [Gracilibacillus lacisalsi].	50.54	93	46	0	24	116	8	100	2e-25	106
rs:WP_029562647	phosphoribosyl-ATP pyrophosphatase, partial [Yersinia pestis].	47.87	94	49	0	25	118	12	105	2e-25	103
rs:WP_005301098	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Aeromonas].	50.56	89	44	0	24	112	23	111	2e-25	106
rs:WP_046718131	phosphoribosyl-AMP cyclohydrolase [Myxococcus fulvus].	50.48	105	50	2	11	114	1	104	2e-25	105
rs:WP_006010728	histidine biosynthesis bifunctional protein hisIE [Glaciecola pallidula].	46.15	91	49	0	24	114	18	108	2e-25	105
rs:WP_035342234	phosphoribosyl-ATP pyrophosphatase [Dickeya sp. DW 0440].	47.78	90	47	0	24	113	17	106	2e-25	105
rs:WP_045260396	phosphoribosyl-ATP pyrophosphatase [Enterobacter sp. 35669].	48.31	89	46	0	24	112	17	105	2e-25	105
rs:WP_019597718	phosphoribosyl-AMP cyclohydrolase [Rhodonellum psychrophilum].	44.33	97	53	1	17	112	5	101	2e-25	105
rs:WP_032170902	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	49.44	89	45	0	24	112	17	105	2e-25	105
rs:WP_017790605	phosphoribosyl-AMP cyclohydrolase [Vibrio vulnificus].	51.14	88	43	0	25	112	23	110	3e-25	106
rs:WP_001618672	histidine biosynthesis HisIE [Escherichia coli].	49.44	89	45	0	24	112	17	105	3e-25	105
rs:WP_001358096	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	49.44	89	45	0	24	112	17	105	3e-25	105
rs:WP_026694493	phosphoribosyl-ATP pyrophosphatase [Bacillus kribbensis].	44.92	118	60	2	18	130	6	123	3e-25	106
rs:WP_010340772	phosphoribosyl-AMP cyclohydrolase [Xanthomonas sacchari].	51.69	89	43	0	24	112	23	111	3e-25	105
tr:A0A061NJ67_9BACL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	49.47	95	48	0	18	112	6	100	3e-25	105
rs:WP_027884048	phosphoribosyl-ATP pyrophosphatase [Mesonia mobilis].	45.54	101	52	1	11	111	1	98	3e-25	105
rs:WP_022546827	hypothetical protein [Bacteroidales bacterium CF].	41.18	119	70	0	12	130	3	121	3e-25	105
rs:WP_032181152	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	49.44	89	45	0	24	112	17	105	3e-25	105
rs:WP_047355735	phosphoribosyl-ATP pyrophosphatase [Enterobacter sp. GN02730].	44.25	113	53	1	24	126	17	129	3e-25	105
rs:WP_038498751	phosphoribosyl-ATP pyrophosphatase [Candidatus Baumannia cicadellinicola].	48.42	95	49	0	24	118	17	111	3e-25	105
rs:WP_042716020	phosphoribosyl-ATP pyrophosphatase [Enterobacter sp. B509].	44.25	113	53	1	24	126	17	129	3e-25	105
rs:WP_032680651	phosphoribosyl-ATP pyrophosphatase [Enterobacter sp. BIDMC 30].	44.25	113	53	1	24	126	17	129	3e-25	105
rs:WP_032641587	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	44.25	113	53	1	24	126	17	129	3e-25	105
tr:A0A081DC57_9FLAO	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	48.35	91	47	0	22	112	20	110	3e-25	106
rs:WP_031889788	hypothetical protein, partial [Staphylococcus aureus].	48.35	91	47	0	26	116	1	91	3e-25	104
rs:WP_045418639	phosphoribosyl-ATP pyrophosphatase [Enterobacter asburiae].	44.25	113	53	1	24	126	17	129	3e-25	105
rs:WP_045328119	phosphoribosyl-ATP pyrophosphatase [Enterobacter asburiae].	44.25	113	53	1	24	126	17	129	3e-25	105
rs:WP_045037281	phosphoribosyl-ATP pyrophosphatase [Photobacterium iliopiscarium].	50.00	90	45	0	23	112	13	102	3e-25	105
rs:WP_042048832	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	49.44	89	45	0	24	112	17	105	3e-25	105
rs:WP_010432027	phosphoribosyl-AMP cyclohydrolase [Enterobacter mori].	44.25	113	53	1	24	126	17	129	3e-25	105
rs:WP_032289725	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	49.44	89	45	0	24	112	17	105	3e-25	105
rs:WP_024360023	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Klebsiella].	50.56	89	44	0	24	112	13	101	3e-25	105
sp:HIS3_PYRCJ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	55.06	89	40	0	24	112	26	114	3e-25	103
rs:WP_019130062	phosphoribosyl-AMP cyclohydrolase [Bacteroidales bacterium ph8].	46.60	103	55	0	10	112	5	107	3e-25	105
rs:WP_044865600	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	49.44	89	45	0	24	112	17	105	3e-25	105
rs:WP_021572864	histidine biosynthesis HisIE [Escherichia coli].	49.44	89	45	0	24	112	17	105	3e-25	105
rs:WP_019516870	hypothetical protein [Sphingomonas sp. Mn802worker].	47.96	98	50	1	19	116	13	109	3e-25	103
rs:WP_041079282	phosphoribosyl-ATP pyrophosphatase [Staphylococcus saprophyticus].	44.12	102	57	0	22	123	9	110	3e-25	105
rs:WP_024550499	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Cronobacter].	49.44	89	45	0	24	112	17	105	3e-25	105
rs:WP_043162512	phosphoribosyl-ATP pyrophosphatase [Aeromonas hydrophila].	51.14	88	43	0	25	112	24	111	3e-25	105
rs:WP_033548232	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	49.44	89	45	0	24	112	17	105	3e-25	105
rs:WP_002482382	phosphoribosyl-AMP cyclohydrolase [Staphylococcus saprophyticus].	44.12	102	57	0	22	123	9	110	3e-25	105
tr:T1T5X2_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	46.53	101	52	1	14	112	4	104	3e-25	105
tr:A0A059NDZ9_9BACI	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	57.50	80	34	0	18	97	7	86	3e-25	102
rs:WP_013317724	phosphoribosyl-AMP cyclohydrolase [Dickeya dadantii].	48.89	90	46	0	24	113	17	106	3e-25	105
tr:A0A090QQF1_9GAMM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	48.89	90	46	0	23	112	13	102	3e-25	105
tr:T1ASC9_9ZZZZ	SubName: Full=Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein {ECO:0000313|EMBL:EQD60277.1}; Flags: Fragment;	52.81	89	42	0	24	112	8	96	3e-25	105
rs:WP_009580684	phosphoribosyl-AMP cyclohydrolase [Fulvivirga imtechensis].	47.52	101	47	2	12	112	9	103	3e-25	105
tr:X1D8V6_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_S05445 {ECO:0000313|EMBL:GAH04740.1}; Flags: Fragment;	50.00	86	43	0	31	116	1	86	3e-25	103
rs:WP_038659295	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Enterobacteriaceae].	48.89	90	46	0	24	113	17	106	3e-25	105
rs:WP_004275288	phosphoribosyl-AMP cyclohydrolase [Campylobacter upsaliensis].	43.69	103	57	1	23	125	17	118	3e-25	105
rs:WP_013187540	phosphoribosyl-AMP cyclohydrolase [Croceibacter atlanticus].	45.54	101	50	1	11	111	3	98	3e-25	105
rs:WP_038256535	phosphoribosyl-ATP pyrophosphatase [Yokenella regensburgei].	51.69	89	43	0	24	112	13	101	3e-25	105
rs:WP_009841868	phosphoribosyl-AMP cyclohydrolase [Vibrio sp. AND4].	50.56	89	44	0	24	112	22	110	3e-25	105
tr:D4Z2A5_SPHJU	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:BAI96737.1}; EC=3.5.4.19 {ECO:0000313|EMBL:BAI96737.1};	48.51	101	51	1	14	113	22	122	3e-25	104
rs:WP_039476766	phosphoribosyl-ATP pyrophosphatase [Pedobacter kyungheensis].	45.71	105	56	1	11	114	1	105	3e-25	105
rs:WP_022082005	histidine biosynthesis HisIE [Bacteroides sp. CAG:144].	46.08	102	49	1	11	112	3	98	3e-25	105
tr:B3T2L3_9ZZZZ	SubName: Full=Putative phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:ABZ06822.1};	45.63	103	55	1	19	120	23	125	3e-25	104
rs:WP_002860063	phosphoribosyl-AMP cyclohydrolase [Campylobacter jejuni].	43.75	96	54	0	24	119	18	113	3e-25	105
rs:WP_046374043	phosphoribosyl-ATP pyrophosphatase [Serratia liquefaciens].	46.81	94	50	0	25	118	18	111	3e-25	105
rs:WP_000954928	phosphoribosyl-AMP cyclohydrolase [Escherichia sp. TW14182].	48.31	89	46	0	24	112	17	105	3e-25	105
sp:HIS2_KLEPN	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	50.56	89	44	0	24	112	13	101	3e-25	105
rs:WP_032586372	histidine biosynthesis bifunctional protein HisIE [Campylobacter jejuni].	43.75	96	54	0	24	119	18	113	3e-25	105
rs:WP_038420094	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	44.25	113	53	1	24	126	17	129	3e-25	105
rs:WP_012967603	phosphoribosyl-AMP cyclohydrolase [Klebsiella variicola].	50.56	89	44	0	24	112	13	101	3e-25	105
rs:WP_005427534	phosphoribosyl-AMP cyclohydrolase [Vibrio campbellii].	50.56	89	44	0	24	112	22	110	3e-25	105
rs:WP_010979515	phosphoribosyl-AMP cyclohydrolase [Sulfolobus tokodaii].	50.54	93	46	0	26	118	25	117	3e-25	103
rs:WP_036877330	phosphoribosyl-ATP pyrophosphatase [Prevotella oryzae].	50.00	90	45	0	23	112	9	98	3e-25	105
rs:WP_022210923	histidine biosynthesis HisIE [Bacteroides cellulosilyticus CAG:158].	48.31	89	46	0	24	112	3	91	3e-25	105
rs:WP_014325020	phosphoribosyl-AMP cyclohydrolase [Leuconostoc mesenteroides].	41.82	110	60	1	8	117	3	108	3e-25	103
rs:WP_000954921	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	49.44	89	45	0	24	112	17	105	3e-25	105
rs:WP_045831269	phosphoribosyl-ATP pyrophosphatase [Luteibacter yeojuensis].	52.81	89	42	0	24	112	10	98	3e-25	105
rs:WP_006820734	phosphoribosyl-AMP cyclohydrolase [Yokenella regensburgei].	51.69	89	43	0	24	112	13	101	3e-25	105
sp:HIS3_SULTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.54	93	46	0	26	118	24	116	3e-25	103
rs:WP_032196996	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	49.44	89	45	0	24	112	17	105	3e-25	105
rs:WP_041385907	phosphoribosyl-AMP cyclohydrolase [Sphingobium japonicum].	48.51	101	51	1	14	113	30	130	3e-25	104
rs:WP_012324710	phosphoribosyl-AMP cyclohydrolase [Shewanella woodyi].	48.57	105	50	1	24	128	22	122	3e-25	105
tr:F4GI26_SPICD	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	53.93	89	41	0	24	112	11	99	3e-25	105
rs:WP_032238961	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	49.44	89	45	0	24	112	17	105	3e-25	105
rs:WP_007832614	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacteroides].	48.31	89	46	0	24	112	10	98	3e-25	105
rs:WP_008671773	phosphoribosyl-AMP cyclohydrolase [Bacteroides sp. 9_1_42FAA].	48.31	89	46	0	24	112	10	98	3e-25	105
rs:WP_032181688	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	49.44	89	45	0	24	112	17	105	3e-25	105
rs:WP_034965461	phosphoribosyl-ATP pyrophosphatase [Epilithonimonas sp. FH1].	46.39	97	51	1	17	112	2	98	3e-25	105
tr:E3PW38_CLOSD	SubName: Full=HisI protein {ECO:0000313|EMBL:CBH20653.1}; EC=3.5.4.19 {ECO:0000313|EMBL:CBH20653.1};	42.45	106	60	1	11	116	5	109	3e-25	103
rs:WP_026773386	phosphoribosyl-ATP pyrophosphatase [Sediminibacterium sp. OR43].	48.86	88	45	0	24	111	11	98	3e-25	105
rs:WP_038169677	phosphoribosyl-AMP cyclohydrolase [Verrucomicrobium sp. BvORR106].	48.00	100	51	1	19	117	21	120	3e-25	103
rs:WP_001723632	phosphoribosyl-ATP diphosphatase [Escherichia coli].	49.44	89	45	0	24	112	17	105	3e-25	105
rs:WP_041395860	phosphoribosyl-ATP pyrophosphatase [Sphaerochaeta coccoides].	53.93	89	41	0	24	112	10	98	3e-25	105
rs:WP_021545652	histidine biosynthesis HisIE [Escherichia coli].	49.44	89	45	0	24	112	17	105	3e-25	105
rs:WP_045737126	phosphoribosyl-ATP pyrophosphatase [Xanthomonas sp. MUS 060].	49.00	100	50	1	14	112	13	112	3e-25	105
rs:WP_008866689	phosphoribosyl-AMP cyclohydrolase [Flavobacteria bacterium MS024-2A].	46.53	101	52	1	16	114	2	102	3e-25	105
rs:WP_016161460	MULTISPECIES: histidine biosynthesis HisIE [Klebsiella].	50.56	89	44	0	24	112	13	101	3e-25	105
rs:WP_045154177	hypothetical protein, partial [Escherichia coli].	48.31	89	46	0	24	112	17	105	3e-25	103
rs:WP_010292409	phosphoribosyl-AMP cyclohydrolase [Leuconostoc pseudomesenteroides].	48.00	100	52	0	19	118	10	109	3e-25	103
rs:WP_013606351	phosphoribosyl-AMP cyclohydrolase [Sphaerochaeta globosa].	47.57	103	48	1	10	112	2	98	3e-25	105
rs:WP_023564911	phosphoribosyl-AMP cyclohydrolase, partial [Escherichia coli].	43.36	113	54	1	24	126	17	129	3e-25	105
rs:WP_035362736	phosphoribosyl-AMP cyclohydrolase [Acetobacter pasteurianus].	45.79	107	56	1	19	123	31	137	3e-25	104
rs:WP_001614846	phosphoribosyl-ATP diphosphatase [Escherichia coli].	49.44	89	45	0	24	112	17	105	3e-25	105
rs:WP_000954830	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Enterobacteriaceae].	43.36	113	54	1	24	126	17	129	3e-25	105
rs:WP_037420110	phosphoribosyl-ATP pyrophosphatase [Serratia grimesii].	46.81	94	50	0	25	118	18	111	4e-25	105
rs:WP_022930994	phosphoribosyl-ATP diphosphatase [Treponema bryantii].	49.48	97	48	1	16	112	242	337	4e-25	108
rs:WP_020281871	phosphoribosyl-AMP cyclohydrolase [Lactobacillus otakiensis].	49.46	93	47	0	24	116	11	103	4e-25	103
rs:WP_022323182	phosphoribosyl-AMP cyclohydrolase [Alistipes sp. CAG:435].	48.00	100	52	0	13	112	2	101	4e-25	105
rs:WP_032658773	phosphoribosyl-ATP pyrophosphatase [Enterobacter sp. DC1].	43.36	113	54	1	24	126	17	129	4e-25	105
rs:WP_047173629	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	43.36	113	54	1	24	126	17	129	4e-25	105
rs:WP_008223543	phosphoribosyl-AMP cyclohydrolase [Vibrionales bacterium SWAT-3].	50.56	89	44	0	24	112	22	110	4e-25	105
rs:WP_025792009	phosphoribosyl-ATP pyrophosphatase [Vibrio parahaemolyticus].	50.56	89	44	0	24	112	22	110	4e-25	105
rs:WP_045623615	phosphoribosyl-ATP pyrophosphatase [Vibrio vulnificus].	51.69	89	43	0	24	112	22	110	4e-25	105
rs:WP_027453398	phosphoribosyl-ATP pyrophosphatase [Prevotella bryantii].	49.44	89	45	0	24	112	10	98	4e-25	105
rs:WP_032304448	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	4e-25	105
rs:WP_023336245	MULTISPECIES: histidine biosynthesis HisIE [Enterobacter].	43.36	113	54	1	24	126	17	129	4e-25	105
rs:WP_045337072	phosphoribosyl-ATP pyrophosphatase [Enterobacter asburiae].	43.36	113	54	1	24	126	17	129	4e-25	105
rs:WP_020894159	phosphoribosyl-AMP cyclohydrolase [Cyclobacterium qasimii].	46.07	89	48	0	24	112	13	101	4e-25	105
rs:WP_026634544	phosphoribosyl-ATP pyrophosphatase [Dyella japonica].	47.62	105	54	1	9	112	2	106	4e-25	105
rs:WP_032325921	hypothetical protein, partial [Shigella flexneri].	48.31	89	46	0	24	112	17	105	4e-25	103
rs:WP_004294708	phosphoribosyl-AMP cyclohydrolase [Bacteroides eggerthii].	46.08	102	49	2	11	112	2	97	4e-25	105
rs:WP_000954721	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	49.44	89	45	0	24	112	17	105	4e-25	105
rs:WP_000954910	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	49.44	89	45	0	24	112	17	105	4e-25	105
rs:WP_016989361	phosphoribosyl-AMP cyclohydrolase [Flavobacterium sp. ACAM 123].	46.81	94	50	0	21	114	8	101	4e-25	105
rs:WP_035415882	phosphoribosyl-ATP pyrophosphatase [Ferrimonas kyonanensis].	50.00	92	46	0	24	115	13	104	4e-25	105
rs:WP_006574517	phosphoribosyl-AMP cyclohydrolase [Pseudoflavonifractor capillosus].	49.50	101	50	1	13	113	2	101	4e-25	102
rs:WP_032487595	phosphoribosyl-ATP pyrophosphatase, partial [Yersinia pestis].	47.87	94	49	0	25	118	18	111	4e-25	103
rs:WP_032250432	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	49.44	89	45	0	24	112	17	105	4e-25	105
rs:WP_017978716	phosphoribosyl-AMP cyclohydrolase [Sphingomonas melonis].	49.49	99	49	1	19	117	14	111	4e-25	103
rs:WP_011302392	phosphoribosyl-AMP cyclohydrolase [Staphylococcus saprophyticus].	44.12	102	57	0	22	123	9	110	4e-25	105
rs:WP_006282983	phosphoribosyl-AMP cyclohydrolase [Prevotella bryantii].	49.44	89	45	0	24	112	10	98	4e-25	105
rs:WP_000954922	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Escherichia].	49.44	89	45	0	24	112	17	105	4e-25	105
rs:WP_045354325	phosphoribosyl-ATP pyrophosphatase [Enterobacter asburiae].	43.36	113	54	1	24	126	17	129	4e-25	105
rs:WP_006743039	phosphoribosyl-AMP cyclohydrolase [Vibrio sp. Ex25].	49.44	89	45	0	24	112	22	110	4e-25	105
tr:A0A0E2LHW6_9GAMM	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:ERF65084.1}; EC=3.5.4.19 {ECO:0000313|EMBL:ERF65084.1}; EC=3.6.1.31 {ECO:0000313|EMBL:ERF65084.1};	50.00	90	45	0	24	113	18	107	4e-25	105
rs:WP_045048225	phosphoribosyl-ATP pyrophosphatase [Rouxiella chamberiensis].	46.81	94	50	0	25	118	18	111	4e-25	105
rs:WP_026770595	phosphoribosyl-ATP pyrophosphatase [Sediminibacterium sp. OR53].	48.86	88	45	0	24	111	11	98	4e-25	105
rs:WP_008434277	phosphoribosyl-AMP cyclohydrolase [Rhodanobacter thiooxydans].	47.12	104	52	1	12	112	3	106	4e-25	105
rs:WP_032184505	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	49.44	89	45	0	24	112	17	105	4e-25	105
rs:WP_044859102	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	44.25	113	53	1	24	126	17	129	4e-25	105
tr:X5DH98_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	47.92	96	49	1	18	112	1	96	4e-25	105
rs:WP_025742072	phosphoribosyl-ATP pyrophosphatase [Aquimarina sp. SW150].	47.25	91	48	0	21	111	8	98	4e-25	105
rs:WP_031227578	phosphoribosyl-ATP pyrophosphatase [Aeromonas veronii].	50.00	90	45	0	24	113	20	109	4e-25	105
rs:WP_047360995	phosphoribosyl-ATP pyrophosphatase [Enterobacter sp. GN02534].	47.19	89	47	0	24	112	17	105	4e-25	105
rs:WP_028912295	phosphoribosyl-ATP pyrophosphatase [Prevotella sp. MA2016].	51.11	90	44	0	23	112	9	98	4e-25	105
rs:WP_014953470	phosphoribosyl-AMP cyclohydrolase [alpha proteobacterium HIMB5].	43.33	120	63	2	17	131	18	137	4e-25	103
gpu:CP006003_5087	phosphoribosyl-AMP cyclohydrolase [Myxococcus fulvus 124B02]	50.49	103	49	2	13	114	2	103	4e-25	105
rs:WP_017383295	phosphoribosyl-AMP cyclohydrolase [Enterobacter cloacae].	49.44	89	45	0	24	112	17	105	4e-25	105
rs:WP_038230069	phosphoribosyl-ATP pyrophosphatase [Vibrio sp. ER1A].	50.56	89	44	0	24	112	19	107	4e-25	105
rs:WP_017073340	phosphoribosyl-AMP cyclohydrolase [Vibrio splendidus].	50.00	90	45	0	23	112	26	115	4e-25	105
rs:WP_013552840	phosphoribosyl-AMP cyclohydrolase [Cellulophaga algicola].	46.53	101	49	1	11	111	3	98	4e-25	105
rs:WP_017108407	phosphoribosyl-AMP cyclohydrolase [Vibrio tasmaniensis].	50.56	89	44	0	24	112	27	115	4e-25	105
rs:WP_017094419	phosphoribosyl-AMP cyclohydrolase [Vibrio splendidus].	50.56	89	44	0	24	112	27	115	4e-25	105
rs:WP_003475180	phosphoribosyl-AMP cyclohydrolase [Xanthomonas translucens].	50.56	89	44	0	24	112	33	121	4e-25	105
rs:WP_021461542	phosphoribosyl-AMP cyclohydrolase [Gallibacterium anatis].	47.87	94	49	0	24	117	17	110	4e-25	105
rs:WP_046659153	phosphoribosyl-ATP pyrophosphatase [Lysobacter capsici].	51.69	89	43	0	24	112	22	110	4e-25	105
rs:WP_013455326	phosphoribosyl-AMP cyclohydrolase [Marivirga tractuosa].	47.78	90	47	0	22	111	10	99	4e-25	105
rs:WP_026955639	phosphoribosyl-ATP pyrophosphatase [Algoriphagus vanfongensis].	49.50	101	45	2	11	111	3	97	4e-25	105
rs:WP_045233211	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	49.44	89	45	0	24	112	17	105	4e-25	105
rs:WP_043134892	phosphoribosyl-ATP pyrophosphatase [Aeromonas salmonicida].	50.56	89	44	0	24	112	23	111	4e-25	105
rs:WP_004734578	phosphoribosyl-AMP cyclohydrolase [Vibrio splendidus].	50.56	89	44	0	24	112	27	115	4e-25	105
gp:X03974_1	E. coli hisIE gene. [Escherichia coli]	49.44	89	45	0	24	112	17	105	4e-25	105
rs:WP_021579318	histidine biosynthesis HisIE [Escherichia coli].	45.13	113	52	1	24	126	13	125	4e-25	105
rs:WP_045404473	phosphoribosyl-ATP pyrophosphatase [Vibrio jasicida].	51.69	89	43	0	24	112	22	110	4e-25	105
rs:WP_040073563	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	4e-25	105
rs:WP_036102832	hypothetical protein, partial [Lysobacter capsici].	51.69	89	43	0	24	112	22	110	4e-25	105
rs:WP_046971460	phosphoribosyl-ATP pyrophosphatase [Dyella japonica].	47.17	106	55	1	13	117	6	111	4e-25	105
tr:B9D5P8_CAMRE	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	46.53	101	52	2	23	121	9	109	4e-25	107
sp:HIS2_PYRFU	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	51.11	90	43	1	24	113	17	105	4e-25	105
rs:WP_006074118	phosphoribosyl-AMP cyclohydrolase [Vibrio shilonii].	50.56	89	44	0	24	112	19	107	4e-25	105
rs:WP_021536905	histidine biosynthesis HisIE [Escherichia coli].	43.36	113	54	1	24	126	17	129	4e-25	105
rs:WP_006828461	phosphoribosyl-ATP pyrophosphatase [Planococcus antarcticus].	44.55	101	56	0	16	116	2	102	5e-25	105
rs:WP_017101633	phosphoribosyl-AMP cyclohydrolase [Vibrio tasmaniensis].	50.56	89	44	0	24	112	27	115	5e-25	105
rs:WP_018345899	phosphoribosyl-AMP cyclohydrolase [Gallibacterium anatis].	47.87	94	49	0	24	117	17	110	5e-25	105
sp:HIS2_ECOLI	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	49.44	89	45	0	24	112	17	105	5e-25	105
tr:W0ERA3_9PORP	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	46.08	102	49	1	11	112	1	96	5e-25	105
rs:WP_020030364	hypothetical protein [gamma proteobacterium SCGC AAA076-P13].	39.50	119	64	2	11	129	1	111	5e-25	105
rs:WP_003696120	phosphoribosyl-AMP cyclohydrolase [Lactobacillus ruminis].	46.94	98	52	0	20	117	5	102	5e-25	102
rs:WP_013746592	phosphoribosyl-AMP cyclohydrolase [Gallibacterium anatis].	47.87	94	49	0	24	117	17	110	5e-25	105
tr:A0A0A8J6D5_ECOLX	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	49.44	89	45	0	24	112	17	105	5e-25	105
rs:WP_020883286	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	44.25	113	53	1	24	126	17	129	5e-25	105
rs:WP_021139326	phosphoribosyl-AMP cyclohydrolase [Aeromonas salmonicida].	50.56	89	44	0	24	112	23	111	5e-25	105
tr:T0CW32_9BACL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	45.10	102	55	1	16	116	12	113	5e-25	106
rs:WP_042037659	phosphoribosyl-ATP pyrophosphatase [Aeromonas popoffii].	51.69	89	43	0	24	112	23	111	5e-25	105
rs:WP_002542146	phosphoribosyl-AMP cyclohydrolase [Grimontia indica].	44.34	106	56	1	24	129	21	123	5e-25	105
rs:WP_033369790	imidazole glycerol phosphate synthase [Bacillus fordii].	47.06	102	54	0	24	125	10	111	5e-25	105
rs:WP_004277812	phosphoribosyl-AMP cyclohydrolase [Campylobacter upsaliensis].	43.30	97	55	0	23	119	17	113	5e-25	105
rs:WP_032241636	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	5e-25	105
rs:WP_010195418	phosphoribosyl-AMP cyclohydrolase [Candidatus Nitrosoarchaeum limnia].	44.68	94	52	0	24	117	15	108	5e-25	102
rs:WP_003904869	phosphoribosyl-ATP diphosphatase [Escherichia coli].	49.44	89	45	0	24	112	17	105	5e-25	105
rs:WP_026442285	phosphoribosyl-AMP cyclohydrolase [Acidobacterium sp. PMMR2].	54.95	91	39	1	24	112	13	103	5e-25	102
rs:WP_005311370	phosphoribosyl-AMP cyclohydrolase [Aeromonas salmonicida].	50.56	89	44	0	24	112	23	111	5e-25	105
rs:WP_031219028	phosphoribosyl-ATP pyrophosphatase [Alicyclobacillus acidoterrestris].	45.10	102	55	1	16	116	8	109	5e-25	106
rs:WP_001403696	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	5e-25	105
tr:A0A0A8J585_ECOLX	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	49.44	89	45	0	24	112	17	105	5e-25	105
rs:WP_039236299	phosphoribosyl-ATP pyrophosphatase [Alteromonas macleodii].	51.11	90	44	0	24	113	18	107	5e-25	105
rs:WP_035455857	phosphoribosyl-ATP pyrophosphatase [Phocaeicola abscessus].	48.45	97	49	1	17	112	2	98	5e-25	105
rs:WP_022948101	phosphoribosyl-AMP cyclohydrolase [Methylohalobius crimeensis].	52.63	114	53	1	18	130	15	128	5e-25	103
rs:WP_009848800	phosphoribosyl-AMP cyclohydrolase [Vibrio sp. MED222].	43.48	115	52	1	11	112	1	115	5e-25	105
rs:WP_039168965	phosphoribosyl-ATP pyrophosphatase [Gallibacterium anatis].	47.87	94	49	0	24	117	17	110	5e-25	105
rs:WP_002951848	histidine biosynthesis bifunctional protein hisIE [Campylobacter showae].	45.54	101	53	2	23	121	9	109	5e-25	106
rs:WP_033568402	phosphoribosyl-ATP pyrophosphatase [Dickeya sp. 2B12].	46.67	90	48	0	24	113	17	106	5e-25	105
rs:WP_014203785	phosphoribosyl-AMP cyclohydrolase [Owenweeksia hongkongensis].	43.20	125	57	3	11	126	3	122	5e-25	105
rs:WP_021958638	phosphoribosyl-AMP cyclohydrolase [Brachyspira sp. CAG:700].	44.00	100	56	0	13	112	5	104	5e-25	105
rs:WP_012604372	phosphoribosyl-AMP cyclohydrolase [Vibrio tasmaniensis].	43.48	115	52	1	11	112	1	115	5e-25	105
rs:WP_039778694	phosphoribosyl-AMP cyclohydrolase, partial [Leuconostoc inhae].	47.47	99	49	1	17	112	6	104	5e-25	102
rs:WP_000954909	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	49.44	89	45	0	24	112	17	105	5e-25	105
rs:WP_005841211	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacteroides].	48.31	89	46	0	24	112	10	98	5e-25	105
rs:WP_043555635	phosphoribosyl-ATP pyrophosphatase [Aeromonas bestiarum].	50.56	89	44	0	24	112	23	111	5e-25	105
rs:WP_038813907	phosphoribosyl-ATP pyrophosphatase, partial [Campylobacter jejuni].	42.71	96	55	0	24	119	18	113	5e-25	103
rs:WP_024233734	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	5e-25	105
rs:WP_036114619	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Luteibacter].	49.00	100	50	1	14	112	3	102	5e-25	105
rs:WP_029846006	phosphoribosyl-ATP pyrophosphatase, partial [Vibrio parahaemolyticus].	50.00	88	44	0	25	112	23	110	5e-25	103
tr:A0A0D6N738_9PROT	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:GAN61515.1};	46.73	107	55	1	19	123	30	136	5e-25	104
rs:WP_041909806	hypothetical protein [Candidatus Iainarchaeum andersonii].	48.08	104	47	2	9	112	220	316	5e-25	107
rs:WP_012105321	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Yersinia].	47.87	94	49	0	25	118	18	111	5e-25	105
rs:WP_012441089	phosphoribosyl-AMP cyclohydrolase [Erwinia tasmaniensis].	47.37	95	50	0	24	118	17	111	5e-25	105
rs:WP_004910477	phosphoribosyl-AMP cyclohydrolase [Leuconostoc pseudomesenteroides].	47.00	100	53	0	19	118	10	109	5e-25	102
tr:A0A094SSI6_9ZZZZ	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGA21773.1};	51.58	95	46	0	18	112	6	100	5e-25	102
rs:WP_032306153	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	5e-25	105
rs:WP_008455044	phosphoribosyl-AMP cyclohydrolase [Enterobacter sp. Ag1].	50.56	89	44	0	24	112	17	105	6e-25	105
rs:WP_014020799	phosphoribosyl-AMP cyclohydrolase [Cyclobacterium marinum].	44.94	89	49	0	24	112	13	101	6e-25	105
rs:WP_034665909	phosphoribosyl-ATP pyrophosphatase [Cellulophaga sp. E6(2014)].	46.53	101	49	1	11	111	3	98	6e-25	104
rs:WP_001536167	histidine biosynthesis HisIE [Escherichia coli].	49.44	89	45	0	24	112	17	105	6e-25	105
rs:WP_010440017	phosphoribosyl-AMP cyclohydrolase [Vibrio cyclitrophicus].	50.56	89	44	0	24	112	27	115	6e-25	105
rs:WP_014679264	phosphoribosyl-AMP cyclohydrolase [Solitalea canadensis].	46.74	92	49	0	23	114	9	100	6e-25	104
rs:WP_042044666	phosphoribosyl-ATP pyrophosphatase [Aeromonas simiae].	52.27	88	42	0	25	112	18	105	6e-25	105
rs:WP_034167827	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	6e-25	105
rs:WP_000954866	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	6e-25	105
rs:WP_012667734	phosphoribosyl-AMP cyclohydrolase [Erwinia pyrifoliae].	48.42	95	49	0	24	118	17	111	6e-25	105
rs:WP_001587413	phosphoribosyl-ATP diphosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	6e-25	105
rs:WP_031430011	histidine biosynthesis bifunctional protein HisIE [Vibrio parahaemolyticus].	49.44	89	45	0	24	112	22	110	6e-25	105
tr:A0A080KI30_9GAMM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	43.52	108	60	1	6	112	3	110	6e-25	105
rs:WP_002892611	phosphoribosyl-AMP cyclohydrolase [Campylobacter jejuni].	44.21	95	53	0	25	119	19	113	6e-25	105
tr:A0A0A8J769_ECOLX	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	49.44	89	45	0	24	112	17	105	6e-25	105
rs:WP_003911391	phosphoribosyl-ATP diphosphatase [Escherichia coli].	49.44	89	45	0	24	112	17	105	6e-25	105
rs:WP_039268421	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	6e-25	104
rs:WP_001774927	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	6e-25	104
tr:A0A021W9G5_9GAMM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	51.69	89	43	0	24	112	8	96	6e-25	105
rs:WP_002886571	phosphoribosyl-AMP cyclohydrolase [Campylobacter jejuni].	42.72	103	58	1	24	126	18	119	6e-25	105
rs:WP_034219885	phosphoribosyl-ATP pyrophosphatase [Arenimonas donghaensis].	50.00	94	47	0	21	114	13	106	6e-25	105
rs:WP_014884472	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Enterobacter].	43.36	113	54	1	24	126	17	129	6e-25	104
rs:WP_047344777	phosphoribosyl-ATP pyrophosphatase [Enterobacter sp. GN02266].	43.36	113	54	1	24	126	17	129	6e-25	104
rs:WP_035681024	phosphoribosyl-ATP pyrophosphatase [Flavobacterium reichenbachii].	48.86	88	45	0	24	111	11	98	6e-25	104
rs:WP_010601636	phosphoribosyl-AMP cyclohydrolase [Pedobacter agri].	45.45	99	53	1	17	114	2	100	6e-25	104
rs:WP_031890735	phosphoribosyl-ATP pyrophosphatase, partial [Staphylococcus aureus].	48.35	91	47	0	26	116	1	91	6e-25	103
rs:WP_009962728	phosphoribosyl-AMP cyclohydrolase [Verrucomicrobium spinosum].	48.00	100	51	1	19	117	28	127	6e-25	103
rs:WP_039861459	imidazole glycerol phosphate synthase [Lachnospiraceae bacterium 6_1_37FAA].	44.66	103	55	1	11	113	1	101	6e-25	104
rs:WP_011410958	phosphoribosyl-AMP cyclohydrolase [Sodalis glossinidius].	43.93	107	60	0	25	131	19	125	6e-25	104
rs:WP_016790805	phosphoribosyl-AMP cyclohydrolase [Vibrio cyclitrophicus].	50.56	89	44	0	24	112	27	115	6e-25	105
rs:WP_001405368	phosphoribosyl-ATP diphosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	6e-25	104
rs:WP_044470179	phosphoribosyl-ATP pyrophosphatase [Mannheimia sp. MG13].	45.00	100	55	0	24	123	12	111	6e-25	105
rs:WP_032897988	phosphoribosyl-ATP pyrophosphatase [Yersinia bercovieri].	47.37	95	50	0	24	118	17	111	6e-25	104
rs:WP_042020200	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	6e-25	104
rs:WP_007403044	phosphoribosyl-AMP cyclohydrolase [Candidatus Nitrosoarchaeum limnia].	44.68	94	52	0	24	117	15	108	6e-25	102
rs:WP_031520878	phosphoribosyl-ATP pyrophosphatase [Cronobacter sp. 1383].	48.31	89	46	0	24	112	17	105	6e-25	104
rs:WP_039141873	phosphoribosyl-ATP pyrophosphatase [Flavihumibacter solisilvae].	50.00	88	44	0	24	111	11	98	6e-25	104
rs:WP_001658514	phosphoribosyl-ATP diphosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	6e-25	104
rs:WP_045474305	phosphoribosyl-ATP pyrophosphatase [Winogradskyella sp. PG-2].	46.81	94	48	1	20	111	5	98	6e-25	104
rs:WP_044815951	phosphoribosyl-ATP pyrophosphatase, partial [Escherichia coli].	48.31	89	46	0	24	112	17	105	6e-25	104
rs:WP_031782745	phosphoribosyl-ATP pyrophosphatase [Staphylococcus aureus].	48.39	93	48	0	24	116	11	103	6e-25	105
rs:WP_002935143	phosphoribosyl-AMP cyclohydrolase [Campylobacter jejuni].	42.72	103	58	1	24	126	18	119	6e-25	104
rs:WP_032813096	phosphoribosyl-ATP pyrophosphatase [Yersinia mollaretii].	46.32	95	51	0	24	118	17	111	6e-25	104
rs:WP_032646448	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Enterobacter].	43.36	113	54	1	24	126	17	129	6e-25	104
rs:WP_024481222	phosphoribosyl-ATP pyrophosphatase [Cellulophaga baltica].	46.53	101	49	1	11	111	3	98	6e-25	104
rs:WP_000186289	phosphoribosyl-AMP cyclohydrolase [Staphylococcus aureus].	47.31	93	49	0	24	116	11	103	6e-25	105
rs:WP_028121848	phosphoribosyl-ATP pyrophosphatase [Epilithonimonas tenax].	45.36	97	52	1	17	112	2	98	7e-25	104
rs:WP_038205198	phosphoribosyl-ATP pyrophosphatase [Vibrio tubiashii].	51.69	89	43	0	24	112	22	110	7e-25	105
rs:WP_032652638	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	47.19	89	47	0	24	112	17	105	7e-25	104
rs:WP_027485644	phosphoribosyl-ATP pyrophosphatase [Rhodanobacter sp. OR87].	47.62	105	54	1	9	112	2	106	7e-25	105
rs:WP_040000804	phosphoribosyl-ATP pyrophosphatase [Dickeya chrysanthemi].	47.78	90	47	0	24	113	17	106	7e-25	104
rs:WP_032291477	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	7e-25	104
rs:WP_029300836	phosphoribosyl-ATP pyrophosphatase [Aeromonas hydrophila].	49.44	89	45	0	24	112	23	111	7e-25	105
rs:WP_042476561	phosphoribosyl-ATP pyrophosphatase [Bacillus sp. FF3].	50.53	95	47	0	18	112	4	98	7e-25	104
rs:WP_012987486	phosphoribosyl-AMP cyclohydrolase [Xenorhabdus bovienii].	49.44	89	45	0	24	112	17	105	7e-25	104
tr:A0A0A8J7G1_ECOLX	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	48.31	89	46	0	24	112	17	105	7e-25	104
rs:WP_000954912	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	49.44	89	45	0	24	112	17	105	7e-25	104
rs:WP_045087561	phosphoribosyl-ATP pyrophosphatase [Defluviitoga tunisiensis].	51.06	94	45	1	24	117	18	110	7e-25	105
rs:WP_033575632	phosphoribosyl-ATP pyrophosphatase [Dickeya chrysanthemi].	47.78	90	47	0	24	113	17	106	7e-25	104
rs:WP_007573945	phosphoribosyl-AMP cyclohydrolase [Prevotella multisaccharivorax].	48.89	90	46	0	23	112	9	98	7e-25	105
rs:WP_002871280	phosphoribosyl-AMP cyclohydrolase [Campylobacter jejuni].	43.16	95	54	0	25	119	19	113	7e-25	104
rs:WP_011012810	phosphoribosyl-ATP pyrophosphatase [Pyrococcus furiosus].	51.11	90	43	1	24	113	29	117	7e-25	105
rs:WP_012770043	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Dickeya].	47.78	90	47	0	24	113	17	106	7e-25	104
rs:WP_032189369	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	7e-25	104
rs:WP_001720267	phosphoribosyl-ATP diphosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	7e-25	104
rs:WP_002868303	phosphoribosyl-AMP cyclohydrolase [Campylobacter jejuni].	42.72	103	58	1	24	126	18	119	7e-25	104
rs:WP_011990897	phosphoribosyl-AMP cyclohydrolase [Campylobacter jejuni].	44.21	95	53	0	25	119	19	113	7e-25	104
rs:WP_002504009	phosphoribosyl-AMP cyclohydrolase [Staphylococcus epidermidis].	46.81	94	50	0	24	117	10	103	7e-25	104
rs:WP_032095922	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Alteromonas].	48.89	90	46	0	24	113	18	107	7e-25	104
rs:WP_001702834	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	7e-25	104
rs:WP_042307525	phosphoribosyl-ATP pyrophosphatase [Citrobacter werkmanii].	48.31	89	46	0	24	112	17	105	7e-25	104
rs:WP_005157776	phosphoribosyl-AMP cyclohydrolase [Yersinia enterocolitica].	47.37	95	50	0	24	118	17	111	7e-25	104
rs:WP_007869111	phosphoribosyl-AMP cyclohydrolase [Cronobacter sakazakii].	49.44	89	45	0	24	112	17	105	7e-25	104
rs:WP_023318677	histidine biosynthesis HisIE [Klebsiella pneumoniae].	50.56	89	44	0	24	112	13	101	7e-25	104
rs:WP_045526640	phosphoribosyl-ATP pyrophosphatase [Aeromonas hydrophila].	49.44	89	45	0	24	112	23	111	7e-25	104
tr:I7H8S3_ECOLX	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	43.36	113	54	1	24	126	17	129	7e-25	104
tr:B1B4Q0_ECOLX	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	48.31	89	46	0	24	112	17	105	7e-25	104
rs:WP_024561410	phosphoribosyl-ATP pyrophosphatase [Cronobacter pulveris].	49.44	89	45	0	24	112	17	105	7e-25	104
rs:WP_029378292	phosphoribosyl-ATP pyrophosphatase [Staphylococcus xylosus].	49.45	91	46	0	24	114	11	101	7e-25	104
rs:WP_038416354	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	47.19	89	47	0	24	112	17	105	7e-25	104
rs:WP_016231038	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	7e-25	104
rs:WP_005434822	phosphoribosyl-AMP cyclohydrolase [Sutterella wadsworthensis].	52.81	89	42	0	24	112	17	105	7e-25	104
rs:WP_031806669	phosphoribosyl-ATP pyrophosphatase, partial [Staphylococcus aureus].	48.35	91	47	0	26	116	1	91	7e-25	103
tr:A0A0A5N2N0_AERHY	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	49.44	89	45	0	24	112	23	111	7e-25	104
rs:WP_002866582	phosphoribosyl-AMP cyclohydrolase [Campylobacter jejuni].	44.21	95	53	0	25	119	19	113	7e-25	104
rs:WP_008300070	phosphoribosyl-AMP cyclohydrolase [Candidatus Nitrosopumilus salaria].	41.12	107	57	1	11	117	8	108	7e-25	102
rs:WP_027712232	phosphoribosyl-ATP pyrophosphatase [Dickeya chrysanthemi].	47.78	90	47	0	24	113	17	106	7e-25	104
rs:WP_029302974	phosphoribosyl-ATP pyrophosphatase [Aeromonas hydrophila].	49.44	89	45	0	24	112	23	111	7e-25	104
rs:WP_044596687	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	47.19	89	47	0	24	112	17	105	7e-25	104
rs:WP_046834367	phosphoribosyl-ATP pyrophosphatase, partial [Escherichia coli].	48.31	89	46	0	24	112	17	105	7e-25	104
rs:WP_015021039	phosphoribosyl-AMP cyclohydrolase [Candidatus Nitrososphaera gargensis].	44.68	94	52	0	24	117	16	109	7e-25	102
rs:WP_017109915	phosphoribosyl-AMP cyclohydrolase [Vibrio tasmaniensis].	50.00	90	45	0	23	112	26	115	7e-25	105
rs:WP_008430568	phosphoribosyl-ATP pyrophosphatase [Planococcus donghaensis].	45.92	98	53	0	16	113	2	99	7e-25	104
rs:WP_034386983	phosphoribosyl-ATP pyrophosphatase [Hellea balneolensis].	45.63	103	55	1	11	112	1	103	8e-25	104
rs:WP_002863907	phosphoribosyl-AMP cyclohydrolase [Campylobacter jejuni].	43.75	96	54	0	24	119	18	113	8e-25	104
rs:WP_039104815	phosphoribosyl-ATP pyrophosphatase [Frischella perrara].	47.73	88	46	0	25	112	18	105	8e-25	104
rs:WP_044715997	phosphoribosyl-ATP pyrophosphatase, partial [Escherichia coli].	48.31	89	46	0	24	112	17	105	8e-25	104
rs:WP_005287893	phosphoribosyl-AMP cyclohydrolase [Edwardsiella tarda].	50.56	89	44	0	24	112	22	110	8e-25	104
rs:WP_026423646	phosphoribosyl-AMP cyclohydrolase [Actinokineospora inagensis].	49.47	95	48	0	18	112	12	106	8e-25	102
rs:WP_004158288	phosphoribosyl-AMP cyclohydrolase [Erwinia amylovora].	49.47	95	48	0	24	118	17	111	8e-25	104
rs:WP_001463504	phosphoribosyl-ATP diphosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	8e-25	104
rs:WP_039100209	phosphoribosyl-ATP pyrophosphatase [Klebsiella pneumoniae].	50.56	89	44	0	24	112	13	101	8e-25	104
rs:WP_004203593	MULTISPECIES: histidine biosynthesis bifunctional protein HisIE [Klebsiella].	50.56	89	44	0	24	112	13	101	8e-25	104
rs:WP_044229309	phosphoribosyl-ATP pyrophosphatase [Coprobacter sp. 177].	45.10	102	50	1	11	112	3	98	8e-25	104
rs:WP_021280157	phosphoribosyl-AMP cyclohydrolase [Mannheimia haemolytica].	45.00	100	55	0	24	123	12	111	8e-25	104
rs:WP_027492647	phosphoribosyl-ATP pyrophosphatase [Rhodanobacter sp. OR444].	50.56	89	44	0	24	112	18	106	8e-25	104
gp:ECORFBM_9	hisIE ORF [Escherichia coli]	48.31	89	46	0	24	112	17	105	8e-25	104
rs:WP_004180498	phosphoribosyl-AMP cyclohydrolase [Klebsiella pneumoniae].	50.56	89	44	0	24	112	13	101	8e-25	104
rs:WP_038529204	phosphoribosyl-ATP pyrophosphatase [Formosa agariphila].	48.35	91	47	0	21	111	8	98	8e-25	104
rs:WP_035596053	phosphoribosyl-ATP pyrophosphatase [Edwardsiella tarda].	50.56	89	44	0	24	112	22	110	8e-25	104
rs:WP_008314743	phosphoribosyl-AMP cyclohydrolase [Leptolyngbya sp. PCC 6406].	47.32	112	57	1	19	128	23	134	8e-25	103
tr:Q67KI1_SYMTH	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	56.52	92	39	1	35	126	3	93	8e-25	104
rs:WP_020266911	MULTISPECIES: hypothetical protein [unclassified Thaumarchaeota (miscellaneous)].	51.11	90	44	0	23	112	15	104	8e-25	102
rs:WP_010605479	phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas flavipulchra].	46.46	99	53	0	14	112	7	105	8e-25	104
rs:WP_033145953	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	43.36	113	54	1	24	126	17	129	8e-25	104
tr:J9F686_9ZZZZ	SubName: Full=Phosphoribosyl-ATP diphosphatase {ECO:0000313|EMBL:EJW90401.1};	47.06	102	48	2	11	112	1	96	8e-25	104
rs:WP_002475436	phosphoribosyl-AMP cyclohydrolase [Staphylococcus epidermidis].	49.45	91	46	0	24	114	10	100	8e-25	104
rs:WP_019446758	phosphoribosyl-AMP cyclohydrolase [Aeromonas sp. 159].	50.56	89	44	0	24	112	28	116	8e-25	104
rs:WP_044549391	phosphoribosyl-ATP pyrophosphatase [Serratia liquefaciens].	45.74	94	51	0	25	118	18	111	8e-25	104
rs:WP_023154856	phosphoribosyl-ATP diphosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	8e-25	104
rs:WP_042818240	phosphoribosyl-ATP pyrophosphatase [Yersinia sp. WP-930601].	50.00	88	44	0	25	112	18	105	8e-25	104
rs:WP_000954878	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	8e-25	104
rs:WP_042866302	phosphoribosyl-ATP pyrophosphatase [Aeromonas piscicola].	50.56	89	44	0	24	112	23	111	8e-25	104
rs:WP_034773966	phosphoribosyl-ATP pyrophosphatase [Idiomarina salinarum].	48.48	99	50	1	15	112	8	106	8e-25	104
tr:C4UEY5_YERRU	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	45.74	94	51	0	25	118	1	94	8e-25	104
tr:E5B6T1_ERWAM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	49.47	95	48	0	24	118	17	111	8e-25	104
rs:WP_046076641	phosphoribosyl-ATP pyrophosphatase [Escherichia fergusonii].	48.31	89	46	0	24	112	17	105	8e-25	104
rs:WP_029034882	phosphoribosyl-ATP pyrophosphatase [Salinimicrobium terrae].	50.00	88	44	0	24	111	11	98	8e-25	104
rs:WP_021930431	histidine biosynthesis HisIE [Tannerella sp. CAG:118].	45.10	102	50	1	11	112	3	98	8e-25	104
rs:WP_029593279	phosphoribosyl-ATP pyrophosphatase [Cronobacter pulveris].	49.44	89	45	0	24	112	17	105	8e-25	104
rs:WP_036193116	phosphoribosyl-ATP pyrophosphatase [Lysobacter concretionis].	45.10	102	55	1	12	112	3	104	8e-25	104
rs:WP_031370483	phosphoribosyl-ATP pyrophosphatase [Lysobacter antibioticus].	48.42	95	49	0	24	118	16	110	8e-25	104
rs:WP_006249546	phosphoribosyl-AMP cyclohydrolase [Mannheimia haemolytica].	45.00	100	55	0	24	123	12	111	8e-25	104
rs:WP_038253274	phosphoribosyl-ATP pyrophosphatase [Xenorhabdus bovienii].	49.44	89	45	0	24	112	17	105	8e-25	104
rs:WP_000954920	phosphoribosyl-AMP cyclohydrolase [Escherichia sp. 1_1_43].	48.31	89	46	0	24	112	17	105	8e-25	104
rs:WP_047075926	phosphoribosyl-ATP pyrophosphatase [Enterobacter aerogenes].	49.44	89	45	0	24	112	13	101	8e-25	104
rs:WP_046835874	phosphoribosyl-ATP pyrophosphatase [Staphylococcus succinus].	49.46	93	47	0	24	116	11	103	8e-25	104
rs:WP_022423017	phosphoribosyl-ATP diphosphatase [Clostridium sp. CAG:440].	41.96	112	64	1	20	130	5	116	8e-25	104
rs:WP_045990131	phosphoribosyl-ATP pyrophosphatase [Pseudoalteromonas piscicida].	49.46	93	47	0	20	112	13	105	8e-25	104
rs:WP_032319164	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	8e-25	104
rs:WP_024555802	phosphoribosyl-ATP pyrophosphatase [Cronobacter pulveris].	49.44	89	45	0	24	112	17	105	8e-25	104
rs:WP_000954824	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	8e-25	104
rs:WP_000954874	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	8e-25	104
rs:WP_000954890	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	8e-25	104
rs:WP_000954873	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	8e-25	104
rs:WP_008634079	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacillaceae].	44.00	100	56	0	13	112	1	100	9e-25	104
rs:WP_000954919	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	9e-25	104
rs:WP_019669829	hypothetical protein [Eudoraea adriatica].	47.25	91	48	0	21	111	8	98	9e-25	104
rs:WP_026985129	phosphoribosyl-ATP pyrophosphatase [Flavobacterium sp. URHB0058].	48.86	88	45	0	24	111	10	97	9e-25	104
rs:WP_040319374	phosphoribosyl-ATP pyrophosphatase [Aeromonas molluscorum].	48.31	89	46	0	24	112	21	109	9e-25	104
rs:WP_025860613	phosphoribosyl-AMP cyclohydrolase [Acetobacter papayae].	47.52	101	51	1	19	117	31	131	9e-25	103
rs:WP_024226103	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	9e-25	104
rs:WP_016236747	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	9e-25	104
rs:WP_000954831	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Enterobacteriaceae].	48.31	89	46	0	24	112	17	105	9e-25	104
rs:WP_001362959	phosphoribosyl-ATP diphosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	9e-25	104
rs:WP_041146370	phosphoribosyl-ATP pyrophosphatase [Raoultella ornithinolytica].	49.44	89	45	0	24	112	13	101	9e-25	104
rs:WP_046223816	phosphoribosyl-ATP pyrophosphatase [Vibrio sp. ECSMB14106].	50.56	89	44	0	24	112	27	115	9e-25	104
gpu:CP011144_2708	hypothetical protein [Pseudoxanthomonas suwonensis]	49.51	103	46	1	10	112	21	117	9e-25	105
rs:WP_045133782	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	9e-25	104
rs:WP_001687704	phosphoribosyl-ATP diphosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	9e-25	104
rs:WP_016532964	histidine biosynthesis bifunctional protein HisIE [Pasteurella multocida].	48.89	90	46	0	24	113	14	103	9e-25	104
rs:WP_032344987	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	9e-25	104
rs:WP_001714095	phosphoribosyl-ATP diphosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	9e-25	104
tr:E7IB26_ECOLX	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	48.31	89	46	0	24	112	13	101	9e-25	104
rs:WP_015754986	phosphoribosyl-AMP cyclohydrolase [Robiginitalea biformata].	46.67	90	48	0	23	112	10	99	9e-25	104
rs:WP_034173147	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	9e-25	104
rs:WP_007139143	phosphoribosyl-AMP cyclohydrolase [Flavobacterium frigoris].	49.45	91	46	0	24	114	11	101	9e-25	104
rs:WP_042476875	phosphoribosyl-ATP pyrophosphatase [Vibrio maritimus].	50.56	89	44	0	24	112	19	107	9e-25	104
rs:WP_023062941	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	9e-25	104
rs:WP_023312371	histidine biosynthesis HisIE [Enterobacter cloacae].	43.36	113	54	1	24	126	17	129	9e-25	104
rs:WP_001554315	phosphoribosyl-ATP diphosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	9e-25	104
rs:WP_032218253	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	9e-25	104
rs:WP_025288982	phosphoribosyl-ATP pyrophosphatase [Bibersteinia trehalosi].	45.00	100	55	0	24	123	12	111	9e-25	104
rs:WP_024235088	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	9e-25	104
rs:WP_000954823	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	9e-25	104
rs:WP_019675431	phosphoribosyl-AMP cyclohydrolase [Rheinheimera perlucida].	40.87	115	65	1	16	130	7	118	9e-25	104
rs:WP_039263829	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Enterobacter].	43.36	113	54	1	24	126	17	129	9e-25	104
rs:WP_016401106	phosphoribosyl-AMP cyclohydrolase [Agarivorans albus].	49.44	89	45	0	24	112	18	106	9e-25	104
rs:WP_010146030	phosphoribosyl-AMP cyclohydrolase [Serinicoccus profundi].	44.25	113	60	1	11	120	2	114	9e-25	104
sp:HIS2_YERPE	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	47.87	94	49	0	25	118	18	111	9e-25	104
rs:WP_044694413	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	9e-25	104
rs:WP_033870530	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	9e-25	104
rs:WP_032318293	hypothetical protein, partial [Escherichia coli].	47.19	89	47	0	24	112	17	105	9e-25	102
tr:R1GPE3_9GAMM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	48.31	89	46	0	24	112	17	105	9e-25	104
rs:WP_001594225	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	9e-25	104
sp:HIS3_PYRAE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	48.11	106	51	2	16	117	17	122	9e-25	102
rs:WP_017060271	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Vibrio].	50.56	89	44	0	24	112	27	115	9e-25	104
tr:A0A0A8J6Z3_ECOLX	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	48.31	89	46	0	24	112	17	105	9e-25	104
rs:WP_047059489	phosphoribosyl-ATP pyrophosphatase [Edwardsiella tarda].	50.56	89	44	0	24	112	22	110	1e-24	104
tr:W7KXK2_9CREN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	48.48	99	50	1	16	113	11	109	1e-24	102
rs:WP_034458424	phosphoribosyl-ATP pyrophosphatase [Buttiauxella agrestis].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_000954898	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
tr:K6YS24_9ALTE	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	50.56	89	44	0	24	112	3	91	1e-24	103
rs:WP_029588293	phosphoribosyl-ATP pyrophosphatase [Campylobacter jejuni].	44.21	95	53	0	25	119	19	113	1e-24	104
rs:WP_042593494	histidine biosynthesis bifunctional protein HisIE [Yersinia pestis].	47.87	94	49	0	25	118	18	111	1e-24	104
rs:WP_038922634	phosphoribosyl-ATP pyrophosphatase [Dickeya dadantii].	47.78	90	47	0	24	113	17	106	1e-24	104
gpu:CP011591_95	phosphoribosyl-ATP pyrophosphatase [Enterobacter asburiae]	43.36	113	54	1	24	126	17	129	1e-24	104
rs:WP_000954879	MULTISPECIES: histidine biosynthesis bifunctional protein HisIE [Escherichia].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_021534319	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_040986829	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Vibrio].	51.69	89	43	0	24	112	22	110	1e-24	104
rs:WP_012571845	phosphoribosyl-ATP pyrophosphatase [Thermococcus onnurineus].	51.65	91	43	1	23	113	14	103	1e-24	104
rs:WP_002898919	histidine biosynthesis bifunctional protein HisIE [Campylobacter jejuni].	42.71	96	55	0	24	119	18	113	1e-24	104
rs:WP_038816159	phosphoribosyl-ATP pyrophosphatase [Campylobacter jejuni].	44.21	95	53	0	25	119	19	113	1e-24	104
rs:WP_002902845	phosphoribosyl-AMP cyclohydrolase [Campylobacter jejuni].	42.71	96	55	0	24	119	18	113	1e-24	104
rs:WP_000954871	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_021559328	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_001475445	phosphoribosyl-ATP diphosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_019933700	phosphoribosyl-AMP cyclohydrolase [Oceanimonas smirnovii].	45.54	101	54	1	13	112	2	102	1e-24	104
rs:WP_013345216	phosphoribosyl-AMP cyclohydrolase [Ferrimonas balearica].	50.56	89	44	0	24	112	17	105	1e-24	104
rs:WP_036195116	phosphoribosyl-ATP pyrophosphatase [Maribacter antarcticus].	47.73	88	46	0	24	111	4	91	1e-24	103
rs:WP_002928365	phosphoribosyl-AMP cyclohydrolase [Campylobacter jejuni].	44.21	95	53	0	25	119	19	113	1e-24	104
rs:WP_002912710	phosphoribosyl-AMP cyclohydrolase [Campylobacter jejuni].	42.71	96	55	0	24	119	18	113	1e-24	104
rs:WP_000954875	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_033815065	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
sp:HIS2_ECO57	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_044778664	phosphoribosyl-ATP pyrophosphatase [Campylobacter jejuni].	44.21	95	53	0	25	119	19	113	1e-24	104
rs:WP_046080832	phosphoribosyl-ATP pyrophosphatase [Escherichia fergusonii].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_045356770	phosphoribosyl-ATP pyrophosphatase [Enterobacter asburiae].	43.36	113	54	1	24	126	17	129	1e-24	104
rs:WP_029092010	phosphoribosyl-AMP cyclohydrolase [Brochothrix thermosphacta].	48.94	94	47	1	21	113	8	101	1e-24	101
tr:K2ESV3_9BACT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	46.53	101	53	1	18	117	4	104	1e-24	101
rs:WP_002890904	histidine biosynthesis bifunctional protein HisIE [Campylobacter jejuni].	42.71	96	55	0	24	119	18	113	1e-24	104
rs:WP_038534218	phosphoribosyl-ATP pyrophosphatase [Barnesiella viscericola].	43.52	108	55	1	5	112	3	104	1e-24	104
rs:WP_012414888	phosphoribosyl-AMP cyclohydrolase [Elusimicrobium minutum].	46.00	100	53	1	14	112	3	102	1e-24	104
rs:WP_002868829	phosphoribosyl-AMP cyclohydrolase [Campylobacter jejuni].	44.21	95	53	0	25	119	19	113	1e-24	104
sp:HIS2_CAMJE	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	42.71	96	55	0	24	119	18	113	1e-24	104
rs:WP_021544706	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_021541055	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_042895669	phosphoribosyl-ATP pyrophosphatase [Enterobacter aerogenes].	49.44	89	45	0	24	112	13	101	1e-24	104
rs:WP_002856577	phosphoribosyl-AMP cyclohydrolase [Campylobacter jejuni].	44.21	95	53	0	25	119	19	113	1e-24	104
rs:WP_002932443	phosphoribosyl-AMP cyclohydrolase [Campylobacter jejuni].	44.21	95	53	0	25	119	19	113	1e-24	104
rs:WP_039572508	phosphoribosyl-ATP pyrophosphatase [Xanthomonas axonopodis].	51.65	91	44	0	24	114	22	112	1e-24	104
rs:WP_021543354	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_047077030	phosphoribosyl-ATP pyrophosphatase [Enterobacter aerogenes].	49.44	89	45	0	24	112	13	101	1e-24	104
rs:WP_015365817	phosphoribosyl-AMP cyclohydrolase [Enterobacter aerogenes].	49.44	89	45	0	24	112	13	101	1e-24	104
rs:WP_032585724	phosphoribosyl-ATP pyrophosphatase [Campylobacter jejuni].	42.71	96	55	0	24	119	18	113	1e-24	104
rs:WP_038816622	phosphoribosyl-ATP pyrophosphatase [Campylobacter jejuni].	42.71	96	55	0	24	119	18	113	1e-24	104
rs:WP_017020628	phosphoribosyl-AMP cyclohydrolase [Aliivibrio logei].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_042569479	phosphoribosyl-ATP pyrophosphatase [Yersinia intermedia].	46.32	95	51	0	24	118	17	111	1e-24	104
rs:WP_000954877	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_024248062	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_024552620	phosphoribosyl-ATP pyrophosphatase [Cronobacter helveticus].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_043012935	histidine biosynthesis bifunctional protein HisIE [Campylobacter jejuni].	42.71	96	55	0	24	119	18	113	1e-24	104
rs:WP_032163897	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_023281331	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_047363189	phosphoribosyl-ATP pyrophosphatase [Enterobacter sp. GN02283].	47.19	89	47	0	24	112	17	105	1e-24	104
rs:WP_025762993	phosphoribosyl-ATP pyrophosphatase [Dyadobacter tibetensis].	44.44	108	60	0	15	122	7	114	1e-24	104
rs:WP_021577640	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_000954901	phosphoribosyl-AMP cyclohydrolase [Shigella flexneri].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_029392729	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_000954888	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_000954876	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_002496604	phosphoribosyl-AMP cyclohydrolase [Staphylococcus epidermidis].	49.44	89	45	0	24	112	10	98	1e-24	104
rs:WP_006972066	phosphohydrolase [Plesiocystis pacifica].	47.96	98	51	0	16	113	9	106	1e-24	105
tr:A0A0A8J600_ECOLX	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	47.19	89	47	0	24	112	17	105	1e-24	104
rs:WP_045403080	phosphoribosyl-ATP pyrophosphatase [Enterobacter asburiae].	47.19	89	47	0	24	112	17	105	1e-24	104
rs:WP_001503093	phosphoribosyl-ATP diphosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
tr:W1WFC4_ECOLX	SubName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000313|EMBL:ETJ16897.1}; Flags: Fragment;	48.31	89	46	0	24	112	17	105	1e-24	102
rs:WP_017057072	phosphoribosyl-AMP cyclohydrolase [Vibrio kanaloae].	50.56	89	44	0	24	112	27	115	1e-24	104
rs:WP_044779881	phosphoribosyl-ATP pyrophosphatase [Campylobacter jejuni].	44.21	95	53	0	25	119	19	113	1e-24	104
rs:WP_044526423	phosphoribosyl-ATP pyrophosphatase [Francisella philomiragia].	46.07	89	48	0	24	112	16	104	1e-24	104
rs:WP_022331727	phosphoribosyl-ATP diphosphatase [Alistipes sp. CAG:29].	51.69	89	43	0	24	112	19	107	1e-24	104
tr:W0Q0P5_9PAST	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	44.00	100	56	0	24	123	14	113	1e-24	104
tr:E9RSD8_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGC75909.1};	44.76	105	56	1	9	113	83	185	1e-24	105
rs:WP_000954894	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_016239570	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_029488619	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_024240312	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_001600094	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_047366472	phosphoribosyl-ATP pyrophosphatase [Enterobacter sp. GN02226].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_021449278	phosphoribosyl-ATP diphosphatase [Vibrio parahaemolyticus].	49.44	89	45	0	24	112	22	110	1e-24	104
rs:WP_047171918	phosphoribosyl-ATP pyrophosphatase [Staphylococcus xylosus].	49.45	91	46	0	24	114	11	101	1e-24	104
rs:WP_042870241	phosphoribosyl-ATP pyrophosphatase [Dickeya sp. NCPPB 569].	46.67	90	48	0	24	113	17	106	1e-24	104
rs:WP_032239909	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_025913296	phosphoribosyl-ATP pyrophosphatase [Enterobacter sp. 5-4].	47.19	89	47	0	24	112	17	105	1e-24	104
rs:WP_000954896	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
sp:HIS3_SOLUE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	42.59	108	61	1	24	130	10	117	1e-24	102
rs:WP_043100362	phosphoribosyl-ATP pyrophosphatase [Xanthomonadaceae bacterium 3.5X].	45.71	105	56	1	9	112	5	109	1e-24	104
rs:WP_025235302	phosphoribosyl-ATP pyrophosphatase [Mannheimia varigena].	44.00	100	56	0	24	123	11	110	1e-24	104
rs:WP_032324517	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_000954900	phosphoribosyl-AMP cyclohydrolase [Shigella flexneri].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_004864532	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Enterobacteriaceae].	49.44	89	45	0	24	112	13	101	1e-24	103
rs:WP_013526446	phosphoribosyl-ATP pyrophosphatase [Haemophilus influenzae].	44.44	99	55	0	24	122	13	111	1e-24	104
rs:WP_000954899	phosphoribosyl-AMP cyclohydrolase [Shigella flexneri].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_008499451	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Enterobacter].	47.19	89	47	0	24	112	17	105	1e-24	104
rs:WP_046852088	phosphoribosyl-ATP pyrophosphatase [Raoultella ornithinolytica].	49.44	89	45	0	24	112	13	101	1e-24	103
rs:WP_042037920	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	104
rs:WP_041909167	phosphoribosyl-ATP pyrophosphatase [Enterobacter sp. BIDMC 29].	47.19	89	47	0	24	112	17	105	1e-24	104
rs:WP_032711977	phosphoribosyl-ATP pyrophosphatase [Enterobacter aerogenes].	49.44	89	45	0	24	112	13	101	1e-24	103
rs:WP_042523065	phosphoribosyl-ATP pyrophosphatase [Francisella philomiragia].	46.07	89	48	0	24	112	16	104	1e-24	104
rs:WP_027663545	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_032192482	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_034962438	phosphoribosyl-ATP diphosphatase [Campylobacter hyointestinalis].	47.83	92	47	1	24	114	10	101	1e-24	105
rs:WP_004852427	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Klebsiella].	49.44	89	45	0	24	112	13	101	1e-24	103
rs:WP_045379269	phosphoribosyl-ATP pyrophosphatase [Enterobacter aerogenes].	49.44	89	45	0	24	112	13	101	1e-24	103
rs:WP_042200005	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_000954932	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_000954897	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_032250204	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_000954870	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_023277246	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_012980221	phosphoribosyl-AMP cyclohydrolase [Methanocaldococcus sp. FS406-22].	50.00	100	49	1	25	124	22	120	1e-24	102
rs:WP_000954915	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_000954935	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	16	104	1e-24	103
rs:WP_045389238	phosphoribosyl-ATP pyrophosphatase [Enterobacter aerogenes].	49.44	89	45	0	24	112	13	101	1e-24	103
rs:WP_006265797	phosphoribosyl-AMP cyclohydrolase [Myroides odoratimimus].	42.50	120	59	2	18	127	5	124	1e-24	103
rs:WP_000954892	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_032292796	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_008868073	phosphoribosyl-AMP cyclohydrolase [Flavobacteria bacterium MS024-3C].	46.15	91	49	0	21	111	8	98	1e-24	103
rs:WP_015583934	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Enterobacteriaceae].	49.44	89	45	0	24	112	13	101	1e-24	103
rs:WP_013444378	phosphoribosyl-AMP cyclohydrolase [Paludibacter propionicigenes].	48.31	89	46	0	23	111	9	97	1e-24	103
rs:WP_019699422	phosphoribosyl-AMP cyclohydrolase, partial [Mycobacterium avium].	51.69	89	43	0	24	112	2	90	1e-24	101
rs:WP_002506727	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Staphylococcus].	48.39	93	48	0	24	116	10	102	1e-24	104
rs:WP_003986154	phosphoribosyl-ATP diphosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_001700972	phosphoribosyl-ATP diphosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_000954836	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_044545892	phosphoribosyl-ATP pyrophosphatase [Parabacteroides distasonis].	46.67	90	48	0	23	112	9	98	1e-24	103
rs:WP_000954934	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Enterobacteriaceae].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_023571337	phosphoribosyl-AMP cyclohydrolase [Flavobacterium cauense].	46.15	91	49	0	21	111	8	98	1e-24	103
rs:WP_046883239	phosphoribosyl-ATP pyrophosphatase [Enterobacter aerogenes].	49.44	89	45	0	24	112	13	101	1e-24	103
rs:WP_047063895	phosphoribosyl-ATP pyrophosphatase [Enterobacter aerogenes].	49.44	89	45	0	24	112	13	101	1e-24	103
tr:A0A0D8DIW3_9EURY	SubName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000313|EMBL:KJE48666.1};	45.56	90	49	0	24	113	11	100	1e-24	104
rs:WP_034789907	phosphoribosyl-ATP pyrophosphatase [Ewingella americana].	47.37	95	50	0	24	118	26	120	1e-24	104
rs:WP_000954893	MULTISPECIES: histidine biosynthesis bifunctional protein HisIE [Enterobacteriaceae].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_010377136	phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas piscicida].	46.46	99	53	0	14	112	7	105	1e-24	103
rs:WP_038659086	phosphoribosyl-AMP cyclohydrolase [Sphingomonas taxi].	49.49	99	49	1	19	117	14	111	1e-24	102
rs:WP_015706033	phosphoribosyl-AMP cyclohydrolase [Enterobacter aerogenes].	49.44	89	45	0	24	112	13	101	1e-24	103
rs:WP_045412956	phosphoribosyl-ATP pyrophosphatase [Enterobacter aerogenes].	49.44	89	45	0	24	112	13	101	1e-24	103
rs:WP_037427777	phosphoribosyl-ATP pyrophosphatase [Shewanella sp. POL2].	45.37	108	53	1	5	112	8	109	1e-24	104
rs:WP_001585852	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_000954835	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_047367914	phosphoribosyl-ATP pyrophosphatase [Enterobacter sp. GN02548].	47.19	89	47	0	24	112	17	105	1e-24	103
rs:WP_000954902	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_046465950	phosphoribosyl-ATP pyrophosphatase [Staphylococcus equorum].	48.39	93	48	0	24	116	10	102	1e-24	104
rs:WP_021338565	phosphoribosyl-AMP cyclohydrolase [Staphylococcus equorum].	48.39	93	48	0	24	116	10	102	1e-24	104
rs:WP_024231796	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_039060361	phosphoribosyl-ATP pyrophosphatase [Shigella flexneri].	48.31	89	46	0	24	112	17	105	1e-24	103
tr:A0A0A8J9A8_ECOLX	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_039024983	phosphoribosyl-ATP pyrophosphatase [Enterobacter asburiae].	42.48	113	55	1	24	126	17	129	1e-24	103
rs:WP_001527228	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_045391776	phosphoribosyl-ATP pyrophosphatase [Enterobacter aerogenes].	49.44	89	45	0	24	112	13	101	1e-24	103
tr:A0A094Q5B1_9ZZZZ	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGA18582.1};	45.79	107	56	1	6	112	9	113	1e-24	102
rs:WP_045955470	phosphoribosyl-ATP pyrophosphatase [Vibrio sp. S2757].	50.56	89	44	0	24	112	22	110	1e-24	104
rs:WP_014787094	phosphoribosyl-AMP cyclohydrolase [Terriglobus roseus].	46.15	104	53	2	17	117	5	108	1e-24	101
tr:A0A0A8J636_ECOLX	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_001471737	phosphoribosyl-ATP diphosphatase [Escherichia coli].	42.48	113	55	1	24	126	17	129	1e-24	103
rs:WP_045361499	phosphoribosyl-ATP pyrophosphatase [Enterobacter aerogenes].	49.44	89	45	0	24	112	13	101	1e-24	103
rs:WP_039266702	phosphoribosyl-ATP pyrophosphatase [Enterobacter sp. FB].	42.48	113	55	1	24	126	17	129	1e-24	103
rs:WP_032819005	phosphoribosyl-ATP pyrophosphatase [Yersinia kristensenii].	46.32	95	51	0	24	118	17	111	1e-24	103
rs:WP_001410398	phosphoribosyl-ATP diphosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_036107958	phosphoribosyl-AMP cyclohydrolase [Listeria grayi].	46.00	100	54	0	24	123	11	110	1e-24	101
rs:WP_016896642	phosphoribosyl-AMP cyclohydrolase [Aerococcus viridans].	45.19	104	51	1	9	112	2	99	1e-24	104
rs:WP_005854554	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacteroidales].	46.67	90	48	0	23	112	9	98	1e-24	103
rs:WP_003617536	phosphoribosyl-AMP cyclohydrolase [Komagataeibacter hansenii].	45.79	107	56	1	19	123	31	137	1e-24	103
rs:WP_002882752	phosphoribosyl-AMP cyclohydrolase [Campylobacter jejuni].	43.16	95	54	0	25	119	19	113	1e-24	103
rs:WP_034058929	phosphoribosyl-ATP pyrophosphatase [Lacinutrix sp. PAMC 27137].	46.15	91	49	0	21	111	8	98	1e-24	103
rs:WP_028110605	phosphoribosyl-ATP pyrophosphatase [Ferrimonas futtsuensis].	46.74	92	49	0	24	115	13	104	1e-24	103
rs:WP_014955304	phosphoribosyl-AMP cyclohydrolase [alpha proteobacterium HIMB59].	39.81	108	64	1	12	118	3	110	1e-24	101
rs:WP_044861808	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	1e-24	103
rs:WP_001668682	phosphoribosyl-ATP diphosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_001574672	phosphoribosyl-ATP diphosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_000954832	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_011249204	phosphoribosyl-ATP pyrophosphatase [Thermococcus kodakarensis].	50.55	91	44	1	23	113	16	105	1e-24	103
rs:WP_033402540	phosphoribosyl-ATP pyrophosphatase [Dyadobacter beijingensis].	46.46	99	51	1	16	112	6	104	1e-24	104
rs:WP_000954880	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_000954895	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_001570039	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_021552598	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_018618855	phosphoribosyl-AMP cyclohydrolase [Spirosoma luteum].	45.71	105	52	1	8	112	2	101	1e-24	103
rs:WP_025572739	phosphoribosyl-ATP pyrophosphatase [Flavobacterium sp. JGI 0001001-D01].	48.86	88	45	0	24	111	10	97	1e-24	103
rs:WP_011520574	phosphoribosyl-AMP cyclohydrolase [Candidatus Baumannia cicadellinicola].	42.27	97	56	0	22	118	15	111	1e-24	103
rs:WP_047056493	phosphoribosyl-ATP pyrophosphatase [Enterobacter aerogenes].	49.44	89	45	0	24	112	13	101	1e-24	103
rs:WP_017723141	phosphoribosyl-AMP cyclohydrolase [Staphylococcus xylosus].	49.45	91	46	0	24	114	11	101	1e-24	103
gp:X13462_9	Escherichia coli DNA for histidin operon genes hisGDCBHAFIE. [Escherichia coli]	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_039495273	phosphoribosyl-ATP pyrophosphatase [Pseudoalteromonas elyakovii].	49.46	93	47	0	20	112	13	105	1e-24	103
rs:WP_047045945	phosphoribosyl-ATP pyrophosphatase [Enterobacter aerogenes].	49.44	89	45	0	24	112	13	101	1e-24	103
rs:WP_001560611	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_047089102	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_029804751	phosphoribosyl-ATP pyrophosphatase [Vibrio parahaemolyticus].	50.00	88	44	0	25	112	23	110	1e-24	103
sp:HIS2_SHEON	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	51.69	89	43	0	24	112	21	109	1e-24	103
rs:WP_002867574	phosphoribosyl-AMP cyclohydrolase [Campylobacter jejuni].	43.16	95	54	0	25	119	19	113	1e-24	103
rs:WP_021513124	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	47.19	89	47	0	24	112	17	105	1e-24	103
rs:WP_000954881	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
tr:C7NG19_KYTSD	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	45.22	115	60	1	1	112	1	115	1e-24	104
rs:WP_004590288	phosphoribosyl-AMP cyclohydrolase [Methanocaldococcus villosus].	46.36	110	55	2	18	124	5	113	1e-24	101
rs:WP_032251911	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	1e-24	103
rs:WP_023787794	phosphoribosyl-AMP cyclohydrolase [Hyphomicrobium nitrativorans].	47.83	115	57	2	19	131	27	140	1e-24	102
rs:WP_000954828	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Escherichia].	48.31	89	46	0	24	112	17	105	1e-24	103
rs:WP_032248539	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	1e-24	103
rs:WP_000954857	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	47.19	89	47	0	24	112	17	105	1e-24	103
rs:WP_000954891	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	103
sp:HIS3_METJA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	50.00	100	49	1	25	124	22	120	1e-24	102
rs:WP_028870952	phosphoribosyl-ATP pyrophosphatase [Psychroserpens burtonensis].	48.86	88	45	0	24	111	10	97	1e-24	103
tr:M7AMZ0_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	58.44	77	32	0	38	114	1	77	1e-24	100
rs:WP_032591125	phosphoribosyl-ATP pyrophosphatase [Campylobacter jejuni].	42.71	96	55	0	24	119	18	113	1e-24	103
rs:WP_033869060	hypothetical protein, partial [Escherichia coli].	48.31	89	46	0	24	112	17	105	1e-24	101
rs:WP_020231716	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	49.44	89	45	0	24	112	17	105	1e-24	103
rs:WP_042093326	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	2e-24	103
rs:WP_042528094	phosphoribosyl-ATP pyrophosphatase [Yersinia ruckeri].	45.74	94	51	0	25	118	18	111	2e-24	103
rs:WP_047346464	phosphoribosyl-ATP pyrophosphatase [Enterobacter sp. GN03164].	48.31	89	46	0	24	112	17	105	2e-24	103
rs:WP_033566234	phosphoribosyl-ATP pyrophosphatase [Sphingobacteriaceae bacterium DW12].	47.12	104	49	1	11	114	2	99	2e-24	103
rs:WP_028776719	phosphoribosyl-ATP pyrophosphatase [Shimazuella kribbensis].	47.00	100	53	0	13	112	1	100	2e-24	103
rs:WP_000954907	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	2e-24	103
rs:WP_037593640	phosphoribosyl-ATP pyrophosphatase [Sporosarcina sp. D27].	45.83	96	52	0	17	112	8	103	2e-24	103
tr:C4S8D2_YERMO	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	46.24	93	50	0	26	118	1	93	2e-24	103
rs:WP_010266636	phosphoribosyl-AMP cyclohydrolase [Alistipes timonensis].	50.00	90	45	0	23	112	18	107	2e-24	103
rs:WP_004742027	phosphoribosyl-AMP cyclohydrolase [Vibrio splendidus].	49.44	89	45	0	24	112	22	110	2e-24	103
rs:WP_041205732	phosphoribosyl-ATP pyrophosphatase [Aeromonas media].	50.56	89	44	0	24	112	23	111	2e-24	103
rs:WP_042372405	phosphoribosyl-ATP pyrophosphatase [Bacteroidaceae bacterium MS4].	44.12	102	53	1	11	112	1	98	2e-24	103
rs:WP_015691142	phosphoribosyl-AMP cyclohydrolase [Pasteurella multocida].	47.78	90	47	0	24	113	10	99	2e-24	103
rs:WP_008258594	phosphoribosyl-AMP cyclohydrolase, partial [Flavobacteria bacterium BAL38].	46.88	96	49	1	18	111	3	98	2e-24	103
rs:WP_017098160	phosphoribosyl-AMP cyclohydrolase [Vibrio tasmaniensis].	50.56	89	44	0	24	112	27	115	2e-24	103
rs:WP_014160804	phosphoribosyl-AMP cyclohydrolase [Pseudoxanthomonas spadix].	52.81	89	42	0	24	112	14	102	2e-24	103
tr:F3BYC9_PSESG	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:EGH06179.1}; EC=3.5.4.19 {ECO:0000313|EMBL:EGH06179.1}; Flags: Fragment;	56.25	80	35	0	18	97	8	87	2e-24	100
rs:WP_038625295	phosphoribosyl-ATP pyrophosphatase [Pantoea sp. PSNIH2].	46.32	95	51	0	24	118	17	111	2e-24	103
rs:WP_001494267	phosphoribosyl-ATP diphosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	2e-24	103
rs:WP_044176072	phosphoribosyl-ATP pyrophosphatase [Photobacterium damselae].	45.56	90	49	0	23	112	13	102	2e-24	103
rs:WP_005300161	phosphoribosyl-AMP cyclohydrolase [Photobacterium damselae].	45.56	90	49	0	23	112	13	102	2e-24	103
rs:WP_000954906	phosphoribosyl-AMP cyclohydrolase, partial [Escherichia coli].	48.31	89	46	0	24	112	17	105	2e-24	103
rs:WP_005754735	phosphoribosyl-AMP cyclohydrolase [Pasteurella multocida].	46.81	94	50	0	24	117	10	103	2e-24	103
rs:WP_038241481	phosphoribosyl-ATP pyrophosphatase [Yersinia ruckeri].	45.74	94	51	0	25	118	18	111	2e-24	103
rs:WP_039140827	phosphoribosyl-ATP pyrophosphatase [Gallibacterium anatis].	46.81	94	50	0	24	117	17	110	2e-24	103
rs:WP_000954834	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	2e-24	103
rs:WP_032314596	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	2e-24	103
rs:WP_025326923	phosphoribosyl-ATP pyrophosphatase [Aeromonas hydrophila].	50.56	89	44	0	24	112	23	111	2e-24	103
sp:HIS2_ECOL6	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	48.31	89	46	0	24	112	17	105	2e-24	103
rs:WP_016529435	phosphoribosyl-AMP cyclohydrolase [Klebsiella pneumoniae].	50.56	89	44	0	24	112	13	101	2e-24	103
rs:WP_040522279	phosphoribosyl-ATP pyrophosphatase [Aliiglaciecola lipolytica].	50.56	89	44	0	24	112	18	106	2e-24	103
rs:WP_010381175	phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas rubra].	46.46	99	53	0	14	112	7	105	2e-24	103
rs:WP_011762953	phosphoribosyl-AMP cyclohydrolase [Pyrobaculum islandicum].	52.22	90	43	0	23	112	49	138	2e-24	102
rs:WP_001374037	phosphoribosyl-ATP diphosphatase [Escherichia coli].	42.48	113	55	1	24	126	17	129	2e-24	103
rs:WP_021535066	histidine biosynthesis HisIE [Escherichia coli].	47.19	89	47	0	24	112	17	105	2e-24	103
rs:WP_005506193	phosphoribosyl-AMP cyclohydrolase [Grimontia hollisae].	44.34	106	56	1	24	129	21	123	2e-24	103
rs:WP_021554456	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	2e-24	103
rs:WP_017497484	phosphoribosyl-AMP cyclohydrolase [Flavobacterium sp. WG21].	48.86	88	45	0	24	111	10	97	2e-24	103
rs:WP_032229958	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	2e-24	103
tr:C6HYU6_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	52.27	88	42	0	25	112	16	103	2e-24	104
rs:WP_026352581	phosphoribosyl-AMP cyclohydrolase [Loktanella vestfoldensis].	47.62	105	53	1	19	121	30	134	2e-24	102
rs:WP_000954903	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	2e-24	103
rs:WP_037496089	phosphoribosyl-ATP pyrophosphatase [Sphingobacterium sp. ACCC 05744].	49.45	91	46	0	24	114	9	99	2e-24	103
rs:WP_001526053	phosphoribosyl-ATP diphosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	2e-24	103
rs:WP_010251060	phosphoribosyl-AMP cyclohydrolase [Myroides injenensis].	45.10	102	54	1	11	112	1	100	2e-24	103
rs:WP_014070907	phosphoribosyl-AMP cyclohydrolase [Enterobacter asburiae].	41.59	113	56	1	24	126	17	129	2e-24	103
rs:WP_001676616	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	2e-24	103
rs:WP_006176280	phosphoribosyl-AMP cyclohydrolase [Enterobacter cancerogenus].	43.36	113	54	1	24	126	17	129	2e-24	103
tr:F7M6F8_9BACE	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	46.08	102	49	2	11	112	1	96	2e-24	103
rs:WP_019995127	hypothetical protein [Aureimonas ureilytica].	47.62	105	53	1	14	116	20	124	2e-24	102
rs:WP_034863448	phosphoribosyl-ATP pyrophosphatase [Enterobacteriaceae bacterium B14].	45.26	95	52	0	24	118	17	111	2e-24	103
rs:WP_020231368	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	49.44	89	45	0	24	112	17	105	2e-24	103
rs:WP_014403154	phosphoribosyl-AMP cyclohydrolase [Frateuria aurantia].	49.00	100	50	1	14	112	7	106	2e-24	103
tr:I3YYQ5_AEQSU	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	42.72	103	57	1	11	111	10	112	2e-24	103
rs:WP_020826041	phosphoribosyl-AMP cyclohydrolase [Serratia liquefaciens].	45.74	94	51	0	25	118	18	111	2e-24	103
rs:WP_032257756	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	2e-24	103
tr:A0A0A8J712_ECOLX	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	47.19	89	47	0	24	112	17	105	2e-24	103
rs:WP_023404791	histidine biosynthesis bifunctional protein HisIE [Vibrio halioticoli].	49.45	91	46	0	24	114	22	112	2e-24	103
rs:WP_011709635	phosphoribosyl-AMP cyclohydrolase [Gramella forsetii].	44.33	97	52	1	17	111	2	98	2e-24	103
rs:WP_039163692	phosphoribosyl-ATP pyrophosphatase [Gallibacterium anatis].	46.81	94	50	0	24	117	17	110	2e-24	103
rs:WP_001757489	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	47.19	89	47	0	24	112	17	105	2e-24	103
rs:WP_000954838	MULTISPECIES: histidine biosynthesis bifunctional protein HisIE [Escherichia].	47.19	89	47	0	24	112	17	105	2e-24	103
gp:CP007319_1323	phosphoribosyl-ATP pyrophosphatase [Salmonella enterica subsp. enterica serovar Enteritidis str.]	51.22	82	40	0	26	107	1	82	2e-24	100
rs:WP_016277828	MULTISPECIES: histidine biosynthesis HisIE [Bacteroides].	47.19	89	47	0	24	112	10	98	2e-24	103
rs:WP_023492267	histidine biosynthesis bifunctional protein HisIE [Serratia sp. DD3].	44.21	95	53	0	24	118	17	111	2e-24	103
rs:WP_000954884	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	47.19	89	47	0	24	112	17	105	2e-24	103
rs:WP_045080856	phosphoribosyl-ATP pyrophosphatase [Vitellibacter vladivostokensis].	47.31	93	48	1	19	111	7	98	2e-24	103
rs:WP_042492507	phosphoribosyl-ATP pyrophosphatase [Aequorivita sublithincola].	46.67	90	48	0	22	111	9	98	2e-24	103
rs:WP_021890389	phosphoribosyl-AMP cyclohydrolase [Succinatimonas sp. CAG:777].	49.44	89	45	0	24	112	21	109	2e-24	101
rs:WP_016196256	phosphoribosyl-AMP cyclohydrolase [Arcticibacter svalbardensis].	49.45	91	46	0	24	114	10	100	2e-24	103
rs:WP_032906850	phosphoribosyl-ATP pyrophosphatase [Yersinia intermedia].	46.32	95	51	0	24	118	17	111	2e-24	103
rs:WP_000954869	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	47.19	89	47	0	24	112	17	105	2e-24	103
rs:WP_000954931	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	47.19	89	47	0	24	112	17	105	2e-24	103
rs:WP_022129461	hypothetical protein [Bacteroides sp. CAG:530].	46.88	96	50	1	18	112	3	98	2e-24	103
rs:WP_033115887	phosphoribosyl-ATP pyrophosphatase [Aeromonas sp. AE122].	48.89	90	46	0	24	113	28	117	2e-24	103
rs:WP_000592610	hypothetical protein [Staphylococcus aureus].	49.46	93	47	0	24	116	263	355	2e-24	106
rs:WP_042362078	phosphoribosyl-ATP pyrophosphatase [Staphylococcus xylosus].	49.45	91	46	0	24	114	11	101	2e-24	103
sp:HIS2_XANAC	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	48.00	100	51	1	16	114	13	112	2e-24	103
rs:WP_043129917	phosphoribosyl-ATP pyrophosphatase [Aeromonas media].	50.56	89	44	0	24	112	23	111	2e-24	103
tr:Q702A1_9CREN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	45.05	91	50	0	24	114	20	110	2e-24	101
tr:E6PX79_9ZZZZ	SubName: Full=Phosphoribosyl-AMP cyclohydrolase (Modular protein) {ECO:0000313|EMBL:CBH99538.1};	48.51	101	49	2	15	112	5	105	2e-24	101
rs:WP_001403118	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	2e-24	103
rs:WP_035467834	phosphoribosyl-ATP pyrophosphatase [Algoriphagus mannitolivorans].	50.00	88	44	0	24	111	10	97	2e-24	103
rs:WP_026464512	phosphoribosyl-ATP pyrophosphatase [Adhaeribacter aquaticus].	48.45	97	49	1	17	112	2	98	2e-24	103
rs:WP_010159646	phosphoribosyl-AMP cyclohydrolase [SAR86 cluster bacterium SAR86D].	39.62	106	64	0	13	118	1	106	2e-24	103
rs:WP_026387159	phosphoribosyl-AMP cyclohydrolase [Acidobacteria bacterium KBS 146].	48.96	96	47	1	24	117	14	109	2e-24	100
rs:WP_021570400	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	2e-24	103
rs:WP_010192971	phosphoribosyl-AMP cyclohydrolase [Candidatus Nitrosoarchaeum limnia].	43.62	94	53	0	24	117	15	108	2e-24	100
rs:WP_045458137	phosphoribosyl-ATP pyrophosphatase [Sporocytophaga myxococcoides].	43.14	102	57	1	11	111	2	103	2e-24	103
rs:WP_038179612	phosphoribosyl-ATP pyrophosphatase [Vibrio rhizosphaerae].	52.75	91	43	0	24	114	21	111	2e-24	103
rs:WP_001493163	phosphoribosyl-ATP diphosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	2e-24	103
rs:WP_016240071	histidine biosynthesis HisIE [Escherichia coli].	47.19	89	47	0	24	112	17	105	2e-24	103
rs:WP_025248569	phosphoribosyl-ATP pyrophosphatase [Pasteurella multocida].	47.78	90	47	0	24	113	10	99	2e-24	103
rs:WP_035672383	phosphoribosyl-ATP pyrophosphatase [Flavobacterium sp. 83].	46.15	91	49	0	21	111	8	98	2e-24	103
rs:WP_015463101	phosphoribosyl-AMP cyclohydrolase [Xanthomonas axonopodis].	48.00	100	51	1	16	114	13	112	2e-24	103
rs:WP_039086454	phosphoribosyl-ATP pyrophosphatase [Gallibacterium anatis].	46.81	94	50	0	24	117	17	110	2e-24	103
rs:WP_000954829	phosphoribosyl-AMP cyclohydrolase [Shigella boydii].	48.31	89	46	0	24	112	17	105	2e-24	103
rs:WP_024522422	phosphoribosyl-ATP pyrophosphatase [Edwardsiella hoshinae].	49.44	89	45	0	24	112	22	110	2e-24	103
rs:WP_014668635	phosphoribosyl-AMP cyclohydrolase [Pasteurella multocida].	47.78	90	47	0	24	113	10	99	2e-24	103
tr:K0LCQ3_STAAU	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	48.35	91	47	0	26	116	1	91	2e-24	103
tr:W1B8A4_KLEPN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	48.31	89	46	0	24	112	17	105	2e-24	102
rs:WP_023325611	MULTISPECIES: histidine biosynthesis HisIE [Enterobacter cloacae complex].	46.07	89	48	0	24	112	17	105	2e-24	103
rs:WP_040951757	phosphoribosyl-ATP pyrophosphatase [Paenibacillaceae bacterium G5].	48.42	95	49	0	18	112	8	102	2e-24	103
rs:WP_005930904	MULTISPECIES: histidine biosynthesis HisIE [Bacteroides].	46.08	102	49	2	11	112	2	97	2e-24	103
rs:WP_015702720	phosphoribosyl-AMP cyclohydrolase [Pasteurella multocida].	47.78	90	47	0	24	113	10	99	2e-24	103
rs:WP_046305797	phosphoribosyl-ATP pyrophosphatase [Grimontia sp. AD028].	43.40	106	57	1	24	129	21	123	2e-24	103
rs:WP_015597858	phosphoribosyl-AMP cyclohydrolase [Hyphomicrobium denitrificans].	48.70	115	50	3	19	130	26	134	2e-24	102
tr:A0A0A8J2W2_ECOLX	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	47.19	89	47	0	24	112	17	105	2e-24	103
rs:WP_015809002	phosphoribosyl-AMP cyclohydrolase [Pedobacter heparinus].	49.45	91	46	0	24	114	10	100	2e-24	103
rs:WP_000954887	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	47.19	89	47	0	24	112	17	105	2e-24	103
tr:A8AEJ8_CITK8	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	43.36	113	54	1	24	126	17	129	2e-24	103
tr:A0A0A5ITP4_CITKO	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	43.36	113	54	1	24	126	17	129	2e-24	103
rs:WP_016158498	MULTISPECIES: histidine biosynthesis HisIE [Escherichia].	47.19	89	47	0	24	112	17	105	2e-24	103
rs:WP_020913081	phosphoribosyl-AMP cyclohydrolase [Shewanella piezotolerans].	50.56	89	44	0	24	112	25	113	2e-24	103
rs:WP_014559326	phosphoribosyl-AMP cyclohydrolase [Ignavibacterium album].	45.00	100	54	1	14	112	3	102	2e-24	103
rs:WP_004103655	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Klebsiella].	49.44	89	45	0	24	112	13	101	2e-24	103
rs:WP_000954929	MULTISPECIES: histidine biosynthesis bifunctional protein HisIE [Escherichia].	47.19	89	47	0	24	112	17	105	2e-24	103
rs:WP_021562280	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	2e-24	103
rs:WP_021550988	histidine biosynthesis HisIE [Escherichia coli].	47.19	89	47	0	24	112	17	105	2e-24	103
rs:WP_014773837	phosphoribosyl-AMP cyclohydrolase [Belliella baltica].	47.73	88	46	0	25	112	14	101	2e-24	103
sp:HIS2_PASMU	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	47.78	90	47	0	24	113	10	99	2e-24	103
sp:HIS3_ERYLH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	46.08	102	55	0	19	120	18	119	2e-24	101
rs:WP_000954861	phosphoribosyl-AMP cyclohydrolase [Shigella boydii].	47.19	89	47	0	24	112	17	105	3e-24	103
rs:WP_001543908	histidine biosynthesis HisIE [Escherichia coli].	47.19	89	47	0	24	112	17	105	3e-24	103
rs:WP_034238008	phosphoribosyl-ATP pyrophosphatase [Aquimarina sp. 22II-S11-z7].	44.79	96	51	1	18	111	3	98	3e-24	103
rs:WP_046897026	phosphoribosyl-ATP pyrophosphatase [Serratia marcescens].	45.26	95	52	0	24	118	17	111	3e-24	103
rs:WP_007746888	phosphoribosyl-AMP cyclohydrolase [Oenococcus kitaharae].	45.83	96	52	0	22	117	6	101	3e-24	100
rs:WP_016533995	HisIE protein [Pasteurella multocida].	47.78	90	47	0	24	113	14	103	3e-24	103
rs:WP_032675154	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	46.07	89	48	0	24	112	17	105	3e-24	103
rs:WP_032853155	phosphoribosyl-ATP pyrophosphatase [Pasteurella multocida].	47.78	90	47	0	24	113	8	97	3e-24	103
tr:A0A0D5BZZ4_9ARCH	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:AJW70036.1}; EC=3.5.4.19 {ECO:0000313|EMBL:AJW70036.1};	39.66	116	62	2	2	117	1	108	3e-24	100
tr:A0A0C2CTN5_9DELT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	46.08	102	55	0	16	117	10	111	3e-24	103
rs:WP_006881202	phosphoribosyl-AMP cyclohydrolase [Vibrio brasiliensis].	50.56	89	44	0	24	112	22	110	3e-24	103
rs:WP_046966099	phosphoribosyl-ATP pyrophosphatase [Luteibacter rhizovicinus].	50.56	89	44	0	24	112	13	101	3e-24	103
rs:WP_005825101	phosphoribosyl-AMP cyclohydrolase [Actinobacillus minor].	48.89	90	46	0	24	113	13	102	3e-24	103
rs:WP_000954886	MULTISPECIES: histidine biosynthesis bifunctional protein HisIE [Escherichia].	47.19	89	47	0	24	112	17	105	3e-24	103
rs:WP_013516781	phosphoribosyl-AMP cyclohydrolase [Candidatus Blochmannia vafer].	45.26	95	52	0	24	118	18	112	3e-24	103
rs:WP_037546864	phosphoribosyl-AMP cyclohydrolase, partial [Spirochaeta sp. JC230].	46.43	112	48	3	17	116	7	118	3e-24	100
rs:WP_038212391	phosphoribosyl-ATP pyrophosphatase [Xenorhabdus bovienii].	48.86	88	45	0	25	112	18	105	3e-24	103
rs:WP_039023535	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	47.19	89	47	0	24	112	17	105	3e-24	103
rs:WP_000954885	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	47.19	89	47	0	24	112	17	105	3e-24	103
rs:WP_000954933	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	47.19	89	47	0	24	112	17	105	3e-24	103
gpu:CP011636_2225	phosphoribosyl-ATP pyrophosphatase [Klebsiella oxytoca]	49.44	89	45	0	24	112	13	101	3e-24	103
rs:WP_000954868	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	47.19	89	47	0	24	112	17	105	3e-24	103
tr:T1A2V1_9ZZZZ	SubName: Full=Phosphoribosyl-ATP diphosphatase {ECO:0000313|EMBL:EQD51198.1}; Flags: Fragment;	50.56	89	44	0	24	112	8	96	3e-24	101
rs:WP_022559053	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Xanthomonas].	50.55	91	45	0	24	114	22	112	3e-24	103
rs:WP_000954883	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Enterobacteriaceae].	47.19	89	47	0	24	112	17	105	3e-24	103
rs:WP_024230219	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	3e-24	103
rs:WP_033646740	phosphoribosyl-ATP pyrophosphatase [Serratia marcescens].	45.26	95	52	0	24	118	17	111	3e-24	103
rs:WP_046337218	phosphoribosyl-ATP pyrophosphatase [Xenorhabdus bovienii].	48.86	88	45	0	25	112	18	105	3e-24	103
rs:WP_004122447	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Klebsiella].	49.44	89	45	0	24	112	13	101	3e-24	103
rs:WP_033654609	phosphoribosyl-ATP pyrophosphatase [Serratia marcescens].	45.26	95	52	0	24	118	17	111	3e-24	103
rs:WP_015412268	phosphoribosyl-AMP cyclohydrolase [Methanosarcina mazei].	49.50	101	46	2	13	113	2	97	3e-24	100
rs:WP_042801567	phosphoribosyl-ATP pyrophosphatase [Mannheimia haemolytica].	46.67	90	48	0	24	113	12	101	3e-24	103
rs:WP_018478034	phosphoribosyl-AMP cyclohydrolase [Pontibacter roseus].	45.10	102	50	1	11	112	3	98	3e-24	103
tr:Z9JJ76_XYLFS	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	52.81	89	42	0	24	112	16	104	3e-24	103
tr:A0A0A8J8S0_ECOLX	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	48.31	89	46	0	24	112	13	101	3e-24	102
rs:WP_005640797	phosphoribosyl-AMP cyclohydrolase [Parabacteroides merdae].	47.78	90	47	0	23	112	9	98	3e-24	102
rs:WP_010237994	phosphoribosyl-AMP cyclohydrolase [Citromicrobium bathyomarinum].	46.53	101	54	0	19	119	18	118	3e-24	100
rs:WP_012549885	phosphoribosyl-AMP cyclohydrolase [Aliivibrio salmonicida].	48.31	89	46	0	24	112	17	105	3e-24	103
rs:WP_000954889	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	47.19	89	47	0	24	112	17	105	3e-24	103
rs:WP_039643910	phosphoribosyl-ATP pyrophosphatase [Staphylococcus hyicus].	48.39	93	48	0	24	116	10	102	3e-24	103
rs:WP_038703334	phosphoribosyl-ATP pyrophosphatase [Planococcus sp. PAMC 21323].	43.56	101	57	0	16	116	2	102	3e-24	103
rs:WP_033637763	phosphoribosyl-ATP pyrophosphatase [Serratia marcescens].	45.26	95	52	0	24	118	17	111	3e-24	103
rs:WP_032295107	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	3e-24	103
rs:WP_001564777	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	3e-24	103
rs:WP_041034245	phosphoribosyl-ATP pyrophosphatase [Serratia marcescens].	45.26	95	52	0	24	118	17	111	3e-24	103
rs:WP_026725846	phosphoribosyl-ATP pyrophosphatase [Flavobacterium sasangense].	46.88	96	49	1	18	111	3	98	3e-24	102
rs:WP_047036497	phosphoribosyl-ATP pyrophosphatase [Enterobacter aerogenes].	49.44	89	45	0	24	112	13	101	3e-24	102
rs:WP_026763412	phosphoribosyl-ATP pyrophosphatase [Sediminibacterium salmoneum].	47.73	88	46	0	24	111	11	98	3e-24	102
rs:WP_000954908	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	48.31	89	46	0	24	112	17	105	3e-24	103
rs:WP_046452381	phosphoribosyl-ATP pyrophosphatase [Bacteroides sp. UNK.MGS-14].	47.78	90	47	0	23	112	9	98	3e-24	102
rs:WP_024981803	phosphoribosyl-ATP pyrophosphatase [Flavobacterium succinicans].	48.86	88	45	0	24	111	10	97	3e-24	102
rs:WP_026631144	phosphoribosyl-ATP pyrophosphatase [Dyadobacter alkalitolerans].	47.47	99	50	1	16	112	6	104	3e-24	103
rs:WP_015959638	phosphoribosyl-AMP cyclohydrolase [Enterobacter sp. 638].	43.36	113	54	1	24	126	17	129	3e-24	103
rs:WP_032206755	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	3e-24	103
rs:WP_000954827	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	47.19	89	47	0	24	112	17	105	3e-24	103
rs:WP_024890613	hypothetical protein [Luteimonas huabeiensis].	47.66	107	55	1	13	118	6	112	3e-24	103
rs:WP_012233032	hypothetical protein [Sorangium cellulosum].	45.00	100	55	0	18	117	3	102	3e-24	103
rs:WP_038188022	phosphoribosyl-ATP pyrophosphatase [Xenorhabdus bovienii].	48.31	89	46	0	24	112	17	105	3e-24	103
rs:WP_045105820	phosphoribosyl-ATP pyrophosphatase [Legionella hackeliae].	44.74	114	62	1	3	115	5	118	3e-24	103
rs:WP_033131751	phosphoribosyl-ATP pyrophosphatase [Aeromonas sp. AE235].	49.44	89	45	0	24	112	25	113	3e-24	103
tr:A0A034TS42_9VIBR	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	51.11	90	43	1	24	112	22	111	3e-24	103
rs:WP_046083405	phosphoribosyl-ATP pyrophosphatase [Escherichia fergusonii].	48.31	89	46	0	24	112	17	105	3e-24	103
rs:WP_008773486	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacteroidales].	46.67	90	48	0	23	112	9	98	3e-24	102
tr:A0A0A8J8J7_ECOLX	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	47.19	89	47	0	24	112	17	105	3e-24	102
rs:WP_027325748	phosphoribosyl-ATP pyrophosphatase [Bacteroides pyogenes].	46.08	102	49	2	11	112	2	97	3e-24	102
rs:WP_005360718	phosphoribosyl-AMP cyclohydrolase [Aeromonas veronii].	48.89	90	46	0	24	113	28	117	3e-24	103
tr:A0A0C9PA65_9BACT	SubName: Full=Candidatus Brocadia sinica JPN1 DNA, contig: brosiA {ECO:0000313|EMBL:GAN31731.1};	45.83	96	52	0	18	113	7	102	3e-24	100
rs:WP_038021512	phosphoribosyl-ATP pyrophosphatase [Tatumella morbirosei].	47.37	95	50	0	24	118	17	111	3e-24	103
rs:WP_005761733	phosphoribosyl-AMP cyclohydrolase [Pasteurella bettyae].	44.44	99	55	0	25	123	13	111	3e-24	103
rs:WP_004938812	histidine biosynthesis bifunctional protein hisIE [Serratia marcescens].	45.36	97	53	0	24	120	17	113	3e-24	103
rs:WP_042654822	phosphoribosyl-ATP pyrophosphatase [Aeromonas encheleia].	49.44	89	45	0	24	112	23	111	3e-24	103
rs:WP_008150995	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Parabacteroides].	47.78	90	47	0	23	112	9	98	3e-24	102
rs:WP_032678507	phosphoribosyl-ATP pyrophosphatase [Enterobacter sp. BIDMC 26].	43.36	113	54	1	24	126	17	129	3e-24	102
rs:WP_047043498	phosphoribosyl-ATP pyrophosphatase [Vibrio sp. CAIM 1540].	48.31	89	46	0	24	112	22	110	3e-24	103
rs:WP_038881080	phosphoribosyl-ATP pyrophosphatase [Serratia marcescens].	45.26	95	52	0	24	118	17	111	3e-24	102
rs:WP_005345640	phosphoribosyl-AMP cyclohydrolase [Aeromonas veronii].	48.89	90	46	0	24	113	28	117	3e-24	103
rs:WP_026452065	phosphoribosyl-ATP pyrophosphatase [Aequorivita capsosiphonis].	47.73	88	46	0	24	111	11	98	3e-24	102
rs:WP_040240790	histidine biosynthesis bifunctional protein HisIE [Xanthomonas citri].	47.00	100	52	1	16	114	13	112	3e-24	102
rs:WP_013071429	phosphoribosyl-AMP cyclohydrolase [Zunongwangia profunda].	46.53	101	49	1	11	111	3	98	3e-24	102
rs:WP_025383474	phosphoribosyl-ATP pyrophosphatase [Yersinia similis].	46.32	95	51	0	24	118	17	111	3e-24	102
rs:WP_028018507	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	42.98	114	55	1	23	126	16	129	3e-24	102
rs:WP_043820207	phosphoribosyl-ATP pyrophosphatase [Aeromonas veronii].	48.89	90	46	0	24	113	28	117	3e-24	103
rs:WP_042030921	phosphoribosyl-ATP pyrophosphatase [Aeromonas jandaei].	48.89	90	46	0	24	113	28	117	3e-24	103
rs:WP_039481364	phosphoribosyl-ATP pyrophosphatase [Pectobacterium carotovorum].	44.21	95	53	0	24	118	23	117	3e-24	103
rs:WP_039108135	phosphoribosyl-ATP pyrophosphatase [Flavobacterium sp. AED].	46.15	91	49	0	21	111	8	98	3e-24	102
rs:WP_003365968	phosphoribosyl-AMP cyclohydrolase, partial [Pseudomonas syringae].	56.41	78	34	0	18	95	8	85	3e-24	99.8
rs:WP_021556935	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	47.19	89	47	0	24	112	17	105	3e-24	102
rs:WP_042318146	phosphoribosyl-ATP pyrophosphatase [Citrobacter farmeri].	49.44	89	45	0	24	112	17	105	3e-24	102
tr:C4TQQ4_YERKR	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	46.24	93	50	0	26	118	1	93	3e-24	102
rs:WP_038654642	phosphoribosyl-ATP pyrophosphatase [Mucinivorans hirudinis].	46.81	94	50	0	21	114	6	99	3e-24	102
rs:WP_014512708	phosphoribosyl-AMP cyclohydrolase [Sulfolobus islandicus].	45.00	100	54	1	15	113	10	109	3e-24	100
rs:WP_005502330	phosphoribosyl-AMP cyclohydrolase [Shewanella benthica].	50.55	91	45	0	22	112	19	109	3e-24	103
rs:WP_038201076	phosphoribosyl-ATP pyrophosphatase [Xenorhabdus bovienii].	48.86	88	45	0	25	112	18	105	4e-24	102
rs:WP_020238964	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	49.44	89	45	0	24	112	17	105	4e-24	102
tr:K1YZA8_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	40.37	109	65	0	11	119	1	109	4e-24	102
rs:WP_041516938	phosphoribosyl-ATP pyrophosphatase [Flavobacterium hibernum].	48.86	88	45	0	24	111	10	97	4e-24	102
rs:WP_015548084	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Alistipes].	44.95	109	56	2	5	112	2	107	4e-24	102
rs:WP_032303300	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	4e-24	102
rs:WP_025203706	phosphoribosyl-ATP pyrophosphatase [Enterobacter cloacae].	43.36	113	54	1	24	126	17	129	4e-24	102
rs:WP_025663726	phosphoribosyl-ATP pyrophosphatase [Aquimarina megaterium].	46.15	91	49	0	21	111	8	98	4e-24	102
rs:WP_042078719	phosphoribosyl-ATP pyrophosphatase [Aeromonas sanarellii].	49.44	89	45	0	24	112	23	111	4e-24	103
rs:WP_004413524	phosphoribosyl-AMP cyclohydrolase [Vibrio orientalis].	49.44	89	45	0	24	112	22	110	4e-24	103
rs:WP_010527311	phosphoribosyl-AMP cyclohydrolase [Thermophagus xiamenensis].	47.19	89	47	0	24	112	11	99	4e-24	102
rs:WP_023458629	phosphoribosyl-AMP cyclohydrolase [Asticcacaulis sp. AC466].	52.17	92	44	0	21	112	23	114	4e-24	103
rs:WP_031444174	phosphoribosyl-ATP pyrophosphatase [Arenibacter algicola].	46.15	91	49	0	21	111	8	98	4e-24	102
rs:WP_015377251	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Serratia].	45.26	95	52	0	24	118	17	111	4e-24	102
rs:WP_047357496	phosphoribosyl-ATP pyrophosphatase [Enterobacter sp. GN02204].	43.36	113	54	1	24	126	17	129	4e-24	102
rs:WP_026570228	MULTISPECIES: imidazole glycerol phosphate synthase [Bacillaceae].	49.46	93	47	0	24	116	8	100	4e-24	103
rs:WP_005354653	phosphoribosyl-AMP cyclohydrolase [Aeromonas diversa].	45.63	103	55	1	11	112	3	105	4e-24	102
rs:WP_009636338	phosphoribosyl-AMP cyclohydrolase [Serratia sp. M24T3].	45.26	95	52	0	24	118	17	111	4e-24	102
rs:WP_000954882	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	47.19	89	47	0	24	112	17	105	4e-24	102
rs:WP_017258257	phosphoribosyl-AMP cyclohydrolase [Pedobacter arcticus].	47.25	91	48	0	24	114	10	100	4e-24	102
rs:WP_014963923	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Nitrosopumilus].	42.06	107	56	1	11	117	8	108	4e-24	100
rs:WP_026709074	phosphoribosyl-ATP pyrophosphatase [Flavobacterium frigidarium].	48.35	91	47	0	24	114	11	101	4e-24	102
tr:K1H6H7_BACFG	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	40.98	122	56	3	11	122	12	127	4e-24	102
rs:WP_022702148	phosphoribosyl-AMP cyclohydrolase [Oceanicaulis alexandrii].	50.00	90	45	0	23	112	12	101	4e-24	102
tr:X0SHQ8_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_L01085 {ECO:0000313|EMBL:GAF74651.1};	42.99	107	60	1	18	123	3	109	4e-24	100
rs:WP_032466253	phosphoribosyl-ATP pyrophosphatase [Yersinia pseudotuberculosis].	46.81	94	50	0	25	118	18	111	4e-24	102
rs:WP_000954858	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Shigella].	47.19	89	47	0	24	112	17	105	4e-24	102
tr:B7LUF7_ESCF3	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	48.31	89	46	0	24	112	17	105	4e-24	102
rs:WP_007221113	phosphoribosyl-ATP diphosphatase [planctomycete KSU-1].	44.79	96	53	0	18	113	7	102	4e-24	100
rs:WP_002799707	phosphoribosyl-AMP cyclohydrolase [Campylobacter coli].	43.75	96	54	0	24	119	18	113	4e-24	102
rs:WP_016114006	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacillus].	50.00	90	45	0	24	113	8	97	4e-24	100
rs:WP_032347165	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	48.31	89	46	0	24	112	17	105	4e-24	102
rs:WP_000954856	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	47.19	89	47	0	24	112	17	105	4e-24	102
rs:WP_039126401	phosphoribosyl-ATP pyrophosphatase [Gilliamella apicola].	44.66	103	56	1	11	112	1	103	4e-24	102
rs:WP_006004917	phosphoribosyl-AMP cyclohydrolase [Glaciecola punicea].	49.44	89	45	0	24	112	18	106	4e-24	102
rs:WP_032541030	phosphoribosyl-ATP pyrophosphatase [Bacteroides fragilis].	45.10	102	50	2	11	112	3	98	4e-24	102
rs:WP_022322413	phosphoribosyl-ATP diphosphatase [Parabacteroides merdae CAG:48].	47.78	90	47	0	23	112	9	98	4e-24	102
rs:WP_046578451	phosphoribosyl-ATP pyrophosphatase [Spirosoma radiotolerans].	45.71	105	52	1	8	112	2	101	4e-24	102
rs:WP_033138509	phosphoribosyl-ATP pyrophosphatase [Aeromonas sp. 4287D].	49.44	89	45	0	24	112	28	116	4e-24	102
rs:WP_038097846	hypothetical protein [Thioalkalivibrio sp. HK1].	45.54	101	54	1	18	117	8	108	4e-24	103
tr:A0A0A0EWB3_9GAMM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	52.27	88	42	0	25	112	18	105	4e-24	102
rs:WP_042021867	phosphoribosyl-ATP pyrophosphatase [Aeromonas sobria].	49.44	89	45	0	24	112	28	116	4e-24	102
rs:WP_043137867	phosphoribosyl-ATP pyrophosphatase [Serratia marcescens].	45.26	95	52	0	24	118	17	111	4e-24	102
rs:WP_037073422	hypothetical protein [Pseudoxanthomonas suwonensis].	55.06	89	40	0	24	112	22	110	4e-24	102
rs:WP_005780060	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacteroides].	40.98	122	56	3	11	122	3	118	4e-24	102
rs:WP_032265788	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	4e-24	102
rs:WP_012929943	phosphoribosyl-AMP cyclohydrolase [Spirosoma linguale].	45.71	105	52	1	8	112	2	101	4e-24	102
rs:WP_000954904	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	47.19	89	47	0	24	112	17	105	4e-24	102
rs:WP_046481482	phosphoribosyl-ATP pyrophosphatase [Citrobacter amalonaticus].	48.31	89	46	0	24	112	17	105	4e-24	102
rs:WP_020537358	hypothetical protein [Lewinella cohaerens].	46.15	104	55	1	12	114	3	106	4e-24	102
rs:WP_032708696	phosphoribosyl-ATP pyrophosphatase [Enterobacter aerogenes].	49.44	89	45	0	24	112	13	101	4e-24	102
rs:WP_042567011	phosphoribosyl-ATP pyrophosphatase [Flavobacterium sp. MEB061].	47.73	88	46	0	24	111	10	97	4e-24	102
rs:WP_041207907	phosphoribosyl-ATP pyrophosphatase [Aeromonas jandaei].	48.89	90	46	0	24	113	19	108	4e-24	102
gpu:CP009511_2533	Phosphoribosyl-AMP cyclohydrolase [Methanosarcina mazei SarPi]	58.11	74	31	0	40	113	1	74	4e-24	99.8
rs:WP_005788819	MULTISPECIES: phosphoribosyl-ATP pyrophosphohydrolase [Bacteroides].	40.98	122	56	3	11	122	3	118	4e-24	102
rs:WP_002786530	phosphoribosyl-AMP cyclohydrolase [Campylobacter coli].	47.19	89	47	0	24	112	18	106	4e-24	102
rs:WP_019974640	hypothetical protein [Empedobacter brevis].	42.86	112	55	1	24	126	11	122	4e-24	102
rs:WP_013306832	phosphoribosyl-AMP cyclohydrolase [Maribacter sp. HTCC2170].	43.56	101	52	1	11	111	3	98	4e-24	102
rs:WP_000954905	MULTISPECIES: histidine biosynthesis bifunctional protein HisIE [Escherichia].	47.19	89	47	0	24	112	17	105	4e-24	102
rs:WP_002561500	histidine biosynthesis HisIE [Bacteroides sp. HPS0048].	45.10	102	50	2	11	112	2	97	4e-24	102
rs:WP_013995830	phosphoribosyl-AMP cyclohydrolase [Zobellia galactanivorans].	49.45	91	46	0	21	111	8	98	4e-24	102
rs:WP_016232167	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	47.19	89	47	0	24	112	17	105	5e-24	102
rs:WP_009780179	phosphoribosyl-AMP cyclohydrolase [Leeuwenhoekiella blandensis].	46.81	94	50	0	18	111	3	96	5e-24	102
rs:WP_013581395	phosphoribosyl-AMP cyclohydrolase [Granulicella tundricola].	50.55	91	43	1	24	112	19	109	5e-24	100
gpu:CP011618_5223	phosphoribosyl-ATP pyrophosphatase [Klebsiella oxytoca]	49.44	89	45	0	24	112	13	101	5e-24	102
rs:WP_017024757	phosphoribosyl-AMP cyclohydrolase [Vibrio rumoiensis].	48.31	89	46	0	24	112	30	118	5e-24	102
rs:WP_034976680	phosphoribosyl-ATP pyrophosphatase [Epilithonimonas lactis].	45.36	97	52	1	17	112	2	98	5e-24	102
tr:A0A080KP81_9GAMM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	42.20	109	62	1	5	112	7	115	5e-24	102
rs:WP_038271192	phosphoribosyl-ATP pyrophosphatase [Xylella fastidiosa].	51.65	91	44	0	24	114	22	112	5e-24	102
rs:WP_025867596	phosphoribosyl-ATP pyrophosphatase [Bacteroides nordii].	45.54	101	49	2	11	111	3	97	5e-24	102
rs:WP_034353578	phosphoribosyl-ATP diphosphatase [Helicobacter sp. MIT 09-6949].	49.44	89	45	0	25	113	15	103	5e-24	103
rs:WP_008513350	phosphoribosyl-AMP cyclohydrolase [Mucilaginibacter paludis].	44.44	99	54	1	17	114	2	100	5e-24	102
rs:WP_009649464	phosphoribosyl-ATP pyrophosphatase [Campylobacter sp. FOBRC14].	43.48	92	52	0	23	114	12	103	5e-24	103
rs:WP_000954924	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Enterobacteriaceae].	43.36	113	54	1	24	126	17	129	5e-24	102
rs:WP_021704084	histidine biosynthesis bifunctional protein HisIE [Vibrio proteolyticus].	50.56	89	44	0	24	112	22	110	5e-24	102
rs:WP_022507075	phosphoribosyl-ATP diphosphatase [Bacteroides sp. CAG:98].	47.19	89	47	0	24	112	10	98	5e-24	102
rs:WP_036136378	phosphoribosyl-ATP pyrophosphatase [Lysobacter daejeonensis].	52.27	88	42	0	25	112	24	111	5e-24	102
rs:WP_036786406	phosphoribosyl-ATP pyrophosphatase [Polaribacter sp. Hel1_33_49].	45.05	91	50	0	21	111	8	98	5e-24	102
rs:WP_000954867	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	47.19	89	47	0	24	112	17	105	5e-24	102
rs:WP_037973033	phosphoribosyl-AMP cyclohydrolase, partial [Succinivibrio dextrinosolvens].	48.31	89	46	0	24	112	11	99	5e-24	99.8
tr:K2D0R5_9BACT	SubName: Full=Putative histidine biosynthesis bifunctional protein hisie (Bifunctional phosphoribosyl-amp cyclohydrolase/phosphoribosyl-atp pyrophosphatase protein) {ECO:0000313|EMBL:EKD91732.1}; Flags: Fragment;	48.31	89	46	0	24	112	15	103	5e-24	102
rs:WP_026778048	phosphoribosyl-ATP pyrophosphatase [Polaribacter sp. Hel_I_88].	46.67	90	48	0	22	111	5	94	5e-24	102
rs:WP_044122095	phosphoribosyl-AMP cyclohydrolase [Anaerobiospirillum succiniciproducens].	47.96	98	50	1	16	112	12	109	5e-24	100
rs:WP_039080503	phosphoribosyl-ATP pyrophosphatase [Shigella boydii].	47.19	89	47	0	24	112	17	105	5e-24	102
rs:WP_034915848	phosphoribosyl-ATP pyrophosphatase [Erwinia sp. 9145].	46.32	95	51	0	24	118	17	111	5e-24	102
rs:WP_000954859	phosphoribosyl-AMP cyclohydrolase [Shigella flexneri].	47.19	89	47	0	24	112	17	105	5e-24	102
rs:WP_013688283	phosphoribosyl-AMP cyclohydrolase [Fluviicola taffensis].	46.81	94	50	0	18	111	1	94	5e-24	102
rs:WP_026972522	phosphoribosyl-ATP pyrophosphatase [Aliagarivorans marinus].	47.19	89	47	0	24	112	18	106	5e-24	102
rs:WP_045101760	phosphoribosyl-ATP pyrophosphatase [Aliivibrio wodanis].	48.31	89	46	0	24	112	17	105	5e-24	102
rs:WP_000954923	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	47.19	89	47	0	24	112	17	105	5e-24	102
rs:WP_014715563	phosphoribosyl-AMP cyclohydrolase [Francisella noatunensis].	44.94	89	49	0	24	112	16	104	5e-24	102
tr:W1YDJ7_9ZZZZ	SubName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000313|EMBL:ETJ40446.1}; Flags: Fragment;	47.67	86	45	0	27	112	1	86	5e-24	99.8
rs:WP_009384866	phosphoribosyl-AMP cyclohydrolase [Vibrio sp. N418].	50.56	89	44	0	24	112	22	110	5e-24	102
rs:WP_022353825	hypothetical protein [Bacteroides sp. CAG:875].	48.31	89	46	0	24	112	10	98	5e-24	102
rs:WP_000954833	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	47.19	89	47	0	24	112	17	105	5e-24	102
rs:WP_038619150	phosphoribosyl-ATP pyrophosphatase [Dyella jiangningensis].	48.51	101	51	1	13	112	6	106	5e-24	102
rs:WP_007486788	phosphoribosyl-AMP cyclohydrolase [Bacteroides nordii].	45.10	102	50	2	11	112	2	97	5e-24	102
tr:A0A0A2W278_BEABA	RecName: Full=Imidazoleglycerol-phosphate dehydratase {ECO:0000256|RuleBase:RU000598}; EC=4.2.1.19 {ECO:0000256|RuleBase:RU000598};	51.69	89	43	0	24	112	896	984	5e-24	107
rs:WP_018697090	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Alistipes].	50.56	89	44	0	24	112	19	107	5e-24	102
rs:WP_035237618	phosphoribosyl-AMP cyclohydrolase [Acidobacteriaceae bacterium URHE0068].	48.00	100	50	1	24	121	9	108	5e-24	100
rs:WP_014026578	phosphoribosyl-AMP cyclohydrolase [Pyrolobus fumarii].	48.96	96	49	0	24	119	22	117	5e-24	100
rs:WP_014122140	phosphoribosyl-ATP pyrophosphatase [Thermococcus sp. AM4].	51.65	91	43	1	23	113	16	105	5e-24	102
rs:WP_041586853	phosphoribosyl-AMP cyclohydrolase [Terriglobus saanensis].	49.45	91	44	1	24	112	10	100	5e-24	100
tr:C4T2T6_YERIN	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	46.24	93	50	0	26	118	1	93	5e-24	102
tr:E8V602_TERSS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	49.45	91	44	1	24	112	14	104	5e-24	100
rs:WP_022455949	phosphoribosyl-AMP cyclohydrolase [Parabacteroides sp. CAG:409].	45.56	90	49	0	23	112	10	99	5e-24	102
tr:A0A0A5T3F6_SERMA	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	45.26	95	52	0	24	118	17	111	5e-24	102
rs:WP_015859226	phosphoribosyl-ATP pyrophosphatase [Thermococcus gammatolerans].	50.55	91	44	1	23	113	16	105	5e-24	102
rs:WP_021015604	phosphoribosyl-ATP pyrophosphatase [Serratia sp. ATCC 39006].	48.31	89	46	0	24	112	17	105	5e-24	102
tr:C2W5T0_BACCE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	50.00	82	41	0	32	113	3	84	6e-24	99.4
rs:WP_021785987	hypothetical protein [Ferroplasma sp. Type II].	46.94	98	50	1	18	115	6	101	6e-24	102
rs:WP_019454373	phosphoribosyl-AMP cyclohydrolase [Serratia marcescens].	45.26	95	52	0	24	118	17	111	6e-24	102
rs:WP_012711526	phosphoribosyl-AMP cyclohydrolase [Sulfolobus islandicus].	45.00	100	54	1	15	113	10	109	6e-24	100
rs:WP_022042189	histidine biosynthesis HisIE [Bacteroides caccae CAG:21].	45.10	102	50	2	11	112	3	98	6e-24	102
rs:WP_001563934	histidine biosynthesis HisIE [Escherichia coli].	48.31	89	46	0	24	112	17	105	6e-24	102
rs:WP_033081378	phosphoribosyl-ATP pyrophosphatase [Colwellia psychrerythraea].	49.44	89	45	0	24	112	18	106	6e-24	102
rs:WP_004313661	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacteroides].	45.10	102	50	2	11	112	3	98	6e-24	102
rs:WP_046975625	phosphoribosyl-ATP pyrophosphatase [Photorhabdus temperata].	46.67	90	48	0	23	112	16	105	6e-24	102
rs:WP_039564183	phosphoribosyl-ATP pyrophosphatase [Xanthomonas campestris].	50.56	89	44	0	24	112	22	110	6e-24	102
tr:A0A0C5C7T5_9ARCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	43.62	94	53	0	24	117	15	108	6e-24	99.8
rs:WP_029314506	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Aeromonas].	49.44	89	45	0	24	112	23	111	6e-24	102
rs:WP_040916401	phosphoribosyl-ATP pyrophosphatase, partial [Legionella tunisiensis].	51.69	89	43	0	24	112	16	104	6e-24	102
rs:WP_041151134	phosphoribosyl-ATP diphosphatase, partial [Sulfurovum sp. FS08-3].	50.00	88	44	0	17	104	6	93	6e-24	99.4
rs:WP_033633501	phosphoribosyl-ATP pyrophosphatase [Serratia nematodiphila].	44.21	95	53	0	24	118	17	111	6e-24	102
rs:WP_039662423	phosphoribosyl-ATP pyrophosphatase [Campylobacter subantarcticus].	44.57	92	51	0	24	115	19	110	6e-24	102
rs:WP_018343707	phosphoribosyl-AMP cyclohydrolase [Cytophaga aurantiaca].	46.59	88	47	0	24	111	10	97	6e-24	102
rs:WP_004247598	phosphoribosyl-AMP cyclohydrolase [Proteus mirabilis].	46.07	89	48	0	24	112	16	104	6e-24	102
rs:WP_039059229	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Shigella].	47.19	89	47	0	24	112	17	105	6e-24	102
rs:WP_019961662	hypothetical protein [Woodsholea maritima].	48.89	90	46	0	23	112	15	104	6e-24	102
rs:WP_034906506	phosphoribosyl-ATP pyrophosphatase [Campylobacter sp. MIT 97-5078].	46.07	89	48	0	24	112	16	104	6e-24	102
rs:WP_022841589	phosphoribosyl-AMP cyclohydrolase [Acidobacteriaceae bacterium TAA166].	48.96	96	47	1	24	117	14	109	6e-24	99.8
rs:WP_040072174	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	6e-24	102
rs:WP_016943837	phosphoribosyl-AMP cyclohydrolase [Dickeya zeae].	48.89	90	46	0	24	113	17	106	6e-24	102
rs:WP_041215198	phosphoribosyl-ATP pyrophosphatase [Aeromonas caviae].	49.44	89	45	0	24	112	23	111	6e-24	102
rs:WP_034887673	phosphoribosyl-ATP pyrophosphatase [Erwinia typographi].	47.37	95	50	0	24	118	17	111	6e-24	102
rs:WP_026959942	phosphoribosyl-ATP pyrophosphatase [Aliagarivorans taiwanensis].	46.07	89	48	0	24	112	18	106	6e-24	102
rs:WP_007513010	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Rhodanobacter].	51.11	90	44	0	23	112	17	106	6e-24	102
rs:WP_042863839	phosphoribosyl-ATP pyrophosphatase [Aeromonas hydrophila].	49.44	89	45	0	24	112	23	111	6e-24	102
rs:WP_011760061	phosphoribosyl-AMP cyclohydrolase [Shewanella amazonensis].	50.56	89	44	0	24	112	17	105	6e-24	102
rs:WP_022823663	phosphoribosyl-AMP cyclohydrolase [Hymenobacter norwichensis].	49.44	89	45	0	24	112	9	97	6e-24	102
rs:WP_012367689	phosphoribosyl-AMP cyclohydrolase [Proteus mirabilis].	46.07	89	48	0	24	112	16	104	6e-24	102
rs:WP_005662550	histidine biosynthesis bifunctional protein HisIE [Haemophilus influenzae].	43.43	99	56	0	24	122	13	111	6e-24	102
rs:WP_042343257	histidine biosynthesis bifunctional protein HisIE [Escherichia coli].	46.07	89	48	0	24	112	17	105	6e-24	102
rs:WP_020945393	histidine biosynthesis bifunctional protein [Proteus mirabilis].	46.07	89	48	0	24	112	16	104	6e-24	102
rs:WP_035918384	phosphoribosyl-ATP pyrophosphatase [Legionella fairfieldensis].	42.57	101	57	1	13	112	4	104	6e-24	102
rs:WP_012279621	phosphoribosyl-AMP cyclohydrolase [Francisella philomiragia].	44.94	89	49	0	24	112	16	104	6e-24	102
tr:W6UED9_9SPHI	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	49.45	91	46	0	24	114	10	100	6e-24	102
rs:WP_017018235	phosphoribosyl-AMP cyclohydrolase [Aliivibrio fischeri].	48.31	89	46	0	24	112	17	105	7e-24	102
rs:WP_016955974	hypothetical protein [Catenovulum agarivorans].	47.25	91	48	0	22	112	17	107	7e-24	102
rs:WP_004252088	phosphoribosyl-AMP cyclohydrolase [Proteus mirabilis].	46.07	89	48	0	24	112	16	104	7e-24	102
rs:WP_005939110	histidine biosynthesis HisIE [Bacteroides massiliensis].	47.19	89	47	0	24	112	10	98	7e-24	102
rs:WP_042056000	phosphoribosyl-ATP pyrophosphatase [Aeromonas veronii].	49.44	89	45	0	24	112	20	108	7e-24	102
rs:WP_005418750	phosphoribosyl-AMP cyclohydrolase [Aliivibrio fischeri].	48.31	89	46	0	24	112	17	105	7e-24	102
rs:WP_005336768	phosphoribosyl-AMP cyclohydrolase [Aeromonas veronii].	48.89	90	46	0	24	113	28	117	7e-24	102
rs:WP_040096992	phosphoribosyl-ATP pyrophosphatase [Aeromonas australiensis].	49.44	89	45	0	24	112	23	111	7e-24	102
rs:WP_017355830	phosphoribosyl-AMP cyclohydrolase [Stenotrophomonas maltophilia].	49.44	89	45	0	24	112	22	110	7e-24	102
rs:WP_039410241	phosphoribosyl-ATP pyrophosphatase [Xanthomonas campestris].	50.56	89	44	0	24	112	22	110	7e-24	102
rs:WP_042080816	phosphoribosyl-ATP pyrophosphatase [Aeromonas veronii].	48.89	90	46	0	24	113	28	117	7e-24	102
rs:WP_044653156	phosphoribosyl-ATP pyrophosphatase [Bacteroides acidifaciens].	45.10	102	50	2	11	112	3	98	7e-24	102
rs:WP_034943067	phosphoribosyl-ATP pyrophosphatase [Erwinia oleae].	46.32	95	51	0	24	118	17	111	7e-24	102
rs:WP_008490387	phosphoribosyl-ATP diphosphatase [SAR86 cluster bacterium SAR86E].	46.07	89	48	0	24	112	13	101	7e-24	102
rs:WP_037417896	phosphoribosyl-ATP pyrophosphatase [Shewanella xiamenensis].	50.56	89	44	0	24	112	21	109	7e-24	102
rs:WP_009202717	histidine biosynthesis protein HisIE, partial [Anaerobaculum hydrogeniformans].	48.39	93	48	0	27	119	1	93	7e-24	101
rs:WP_035721240	imidazole glycerol phosphate synthase [Gracilibacillus boraciitolerans].	49.00	100	47	2	24	122	8	104	7e-24	102
rs:WP_024769324	phosphoribosyl-ATP pyrophosphatase [Aquimarina macrocephali].	45.05	91	50	0	21	111	8	98	7e-24	102
rs:WP_037061356	hypothetical protein [Pseudoxanthomonas suwonensis].	55.06	89	40	0	24	112	22	110	7e-24	102
rs:WP_038908140	phosphoribosyl-ATP pyrophosphatase [Dickeya zeae].	48.89	90	46	0	24	113	17	106	7e-24	102
rs:WP_004287953	phosphoribosyl-AMP cyclohydrolase [Francisella philomiragia].	44.94	89	49	0	24	112	16	104	7e-24	102
rs:WP_009316929	phosphoribosyl-AMP cyclohydrolase [Tannerella sp. 6_1_58FAA_CT1].	45.56	90	49	0	23	112	9	98	7e-24	102
rs:WP_005666466	phosphoribosyl-ATP pyrophosphatase [Haemophilus influenzae].	43.43	99	56	0	24	122	13	111	7e-24	102
rs:WP_013202932	phosphoribosyl-AMP cyclohydrolase [Erwinia billingiae].	46.32	95	51	0	24	118	17	111	7e-24	102
rs:WP_000954864	phosphoribosyl-AMP cyclohydrolase [Escherichia albertii].	47.19	89	47	0	24	112	17	105	7e-24	102
tr:A0A0A5LXB4_SERMA	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	45.26	95	52	0	24	118	17	111	7e-24	102
gpu:CP011642_746	phosphoribosyl-ATP pyrophosphatase [Serratia marcescens]	45.26	95	52	0	24	118	17	111	7e-24	102
rs:WP_013922944	phosphoribosyl-AMP cyclohydrolase [Francisella sp. TX077308].	44.94	89	49	0	24	112	16	104	7e-24	102
rs:WP_028982221	phosphoribosyl-ATP pyrophosphatase [Sporocytophaga myxococcoides].	43.56	101	56	1	12	111	3	103	7e-24	102
rs:WP_018113896	hypothetical protein, partial [Staphylococcus sp. JGI 0001002-I23].	48.28	87	45	0	24	110	10	96	8e-24	99.4
rs:WP_015029459	phosphoribosyl-AMP cyclohydrolase [Emticicia oligotrophica].	44.76	105	55	2	17	119	4	107	8e-24	102
rs:WP_022946829	phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas ruthenica].	43.43	99	56	0	14	112	7	105	8e-24	102
rs:WP_042011275	phosphoribosyl-ATP pyrophosphatase [Aeromonas fluvialis].	48.89	90	46	0	24	113	20	109	8e-24	102
rs:WP_038688641	phosphoribosyl-ATP pyrophosphatase [Stenotrophomonas rhizophila].	48.31	89	46	0	24	112	22	110	8e-24	102
rs:WP_028115177	phosphoribosyl-ATP pyrophosphatase [Ferrimonas senticii].	50.00	90	45	0	23	112	20	109	8e-24	102
rs:WP_004244522	phosphoribosyl-AMP cyclohydrolase [Proteus mirabilis].	46.07	89	48	0	24	112	16	104	8e-24	102
rs:WP_004170184	phosphoribosyl-AMP cyclohydrolase [Erwinia amylovora].	47.37	95	50	0	24	118	17	111	8e-24	102
rs:WP_041663003	phosphoribosyl-AMP cyclohydrolase [Acidimicrobium ferrooxidans].	46.43	112	56	3	2	112	1	109	8e-24	99.8
tr:A0A0B0EN39_9BACT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	40.91	110	65	0	17	126	6	115	8e-24	100
rs:WP_036808147	phosphoribosyl-ATP pyrophosphatase [Planomicrobium glaciei].	39.82	113	68	0	18	130	4	116	8e-24	102
rs:WP_027697158	phosphoribosyl-ATP pyrophosphatase [Vibrio litoralis].	49.44	89	45	0	24	112	30	118	8e-24	102
rs:WP_009285228	phosphoribosyl-AMP cyclohydrolase [Fibrisoma limi].	44.23	104	53	1	9	112	3	101	8e-24	102
rs:WP_044750323	phosphoribosyl-ATP pyrophosphatase [Xanthomonas oryzae].	47.00	100	52	1	16	114	13	112	8e-24	102
rs:WP_005757365	phosphoribosyl-AMP cyclohydrolase [Pasteurella multocida].	46.67	90	48	0	24	113	14	103	8e-24	102
rs:WP_007566614	phosphoribosyl-AMP cyclohydrolase [Bacteroides coprocola].	44.12	102	53	1	11	112	1	98	8e-24	102
rs:WP_011178132	phosphoribosyl-ATP pyrophosphatase [Picrophilus torridus].	43.30	97	54	1	17	113	5	100	8e-24	102
rs:WP_007481975	phosphoribosyl-AMP cyclohydrolase [Bacteroides salyersiae].	47.19	89	47	0	24	112	9	97	8e-24	102
rs:WP_041405736	phosphoribosyl-ATP pyrophosphatase [Shewanella denitrificans].	45.71	105	52	1	13	112	6	110	8e-24	102
rs:WP_016238107	histidine biosynthesis HisIE [Escherichia coli].	47.19	89	47	0	24	112	17	105	8e-24	102
tr:Q12NT1_SHEDO	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	45.71	105	52	1	13	112	14	118	9e-24	102
rs:WP_034884411	phosphoribosyl-ATP pyrophosphatase [Gilliamella apicola].	44.55	101	55	1	13	112	1	101	9e-24	101
rs:WP_011261652	phosphoribosyl-AMP cyclohydrolase [Aliivibrio fischeri].	48.31	89	46	0	24	112	17	105	9e-24	102
rs:WP_032824009	phosphoribosyl-ATP pyrophosphatase [Haemophilus influenzae].	43.43	99	56	0	24	122	13	111	9e-24	102
rs:WP_009602812	phosphoribosyl-AMP cyclohydrolase [Vibrio caribbeanicus].	48.89	90	46	0	23	112	21	110	9e-24	102
rs:WP_032176422	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	9e-24	102
rs:WP_010378516	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Xanthomonas].	49.45	91	46	0	24	114	22	112	9e-24	102
rs:WP_005681378	phosphoribosyl-AMP cyclohydrolase [Bacteroides caccae].	45.10	102	50	2	11	112	3	98	9e-24	101
rs:WP_014292472	phosphoribosyl-AMP cyclohydrolase [Oceanimonas sp. GK1].	48.31	89	46	0	24	112	14	102	9e-24	101
rs:WP_042518530	phosphoribosyl-ATP pyrophosphatase [Francisella philomiragia].	44.94	89	49	0	24	112	16	104	9e-24	102
rs:WP_039440609	phosphoribosyl-ATP pyrophosphatase [Xanthomonas vasicola].	49.45	91	46	0	24	114	22	112	9e-24	102
sp:HIS2_HAEIN	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	43.43	99	56	0	24	122	13	111	9e-24	102
rs:WP_039322327	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Pectobacterium].	44.21	95	53	0	24	118	23	117	9e-24	102
rs:WP_004297045	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacteroides].	45.10	102	50	2	11	112	3	98	9e-24	101
tr:A4N2J0_HAEIF	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	43.88	98	55	0	24	121	13	110	9e-24	100
rs:WP_022390778	MULTISPECIES: histidine biosynthesis HisIE [Porphyromonadaceae].	45.56	90	49	0	23	112	9	98	9e-24	101
rs:WP_002806369	phosphoribosyl-AMP cyclohydrolase [Xanthomonas fragariae].	49.45	91	46	0	24	114	22	112	9e-24	102
rs:WP_004406290	phosphoribosyl-AMP cyclohydrolase [Vibrio nigripulchritudo].	49.44	89	45	0	24	112	22	110	9e-24	102
rs:WP_022612852	histidine biosynthesis protein HisIE [Vibrio nigripulchritudo].	49.44	89	45	0	24	112	22	110	9e-24	102
rs:WP_017216836	phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas sp. NJ631].	48.04	102	46	1	11	112	11	105	9e-24	101
rs:WP_035888651	phosphoribosyl-ATP pyrophosphatase [Legionella norrlandica].	45.10	102	55	1	12	112	3	104	9e-24	102
rs:WP_012884943	phosphoribosyl-AMP cyclohydrolase [Dickeya dadantii].	47.78	90	47	0	24	113	17	106	9e-24	101
rs:WP_000954930	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	47.73	88	46	0	25	112	18	105	9e-24	101
rs:WP_024965008	phosphoribosyl-ATP pyrophosphatase [Pantoea sp. IMH].	45.26	95	52	0	24	118	17	111	9e-24	101
rs:WP_016452746	phosphoribosyl-AMP cyclohydrolase [Delftia acidovorans].	49.04	104	51	1	19	120	32	135	9e-24	100
rs:WP_022830649	phosphoribosyl-AMP cyclohydrolase, partial [Cytophagales bacterium B6].	46.74	92	49	0	23	114	9	100	9e-24	99.8
rs:WP_039514625	phosphoribosyl-ATP pyrophosphatase [Pectobacterium carotovorum].	44.21	95	53	0	24	118	23	117	9e-24	102
rs:WP_039505288	phosphoribosyl-ATP pyrophosphatase [Pectobacterium carotovorum].	44.21	95	53	0	24	118	23	117	9e-24	102
rs:WP_039472683	phosphoribosyl-ATP pyrophosphatase [Pectobacterium carotovorum].	44.21	95	53	0	24	118	23	117	9e-24	102
rs:WP_039300638	phosphoribosyl-ATP pyrophosphatase [Pectobacterium betavasculorum].	44.21	95	53	0	24	118	23	117	9e-24	102
rs:WP_042684616	phosphoribosyl-AMP cyclohydrolase [Thaumarchaeota archaeon MY2].	44.44	99	54	1	16	113	6	104	9e-24	99.4
rs:WP_010416428	phosphoribosyl-AMP cyclohydrolase [Anaerophaga thermohalophila].	46.07	89	48	0	24	112	11	99	9e-24	101
rs:WP_018355880	phosphoribosyl-AMP cyclohydrolase [Pasteurella pneumotropica].	46.67	90	48	0	24	113	14	103	9e-24	101
tr:R6DHE5_9BACE	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	45.10	102	50	2	11	112	3	98	9e-24	101
rs:WP_027728033	phosphoribosyl-ATP diphosphatase [Treponema sp. C6A8].	46.09	115	58	2	16	130	242	352	9e-24	104
rs:WP_035643821	phosphoribosyl-ATP pyrophosphatase [Flavobacterium sp. Fl].	47.73	88	46	0	24	111	10	97	9e-24	101
rs:WP_031455347	phosphoribosyl-ATP pyrophosphatase [Flavobacterium chungangense].	47.73	88	46	0	24	111	10	97	9e-24	101
rs:WP_005932032	phosphoribosyl-AMP cyclohydrolase [Xanthomonas axonopodis].	49.45	91	46	0	24	114	22	112	9e-24	101
tr:A0A023D055_9LACO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	48.35	91	47	0	22	112	7	97	1e-23	99.0
rs:WP_010301051	phosphoribosyl-AMP cyclohydrolase [Pectobacterium carotovorum].	44.21	95	53	0	24	118	23	117	1e-23	102
tr:A0A031LV72_9CREN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	45.16	93	51	0	21	113	17	109	1e-23	99.8
tr:A0A090M477_OSTTA	SubName: Full=Phosphoribosyl-ATP pyrophosphohydrolase-like {ECO:0000313|EMBL:CEF97472.1};	44.86	107	57	1	16	120	56	162	1e-23	103
tr:S6EBL2_AVIPA	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	47.87	94	49	0	24	117	3	96	1e-23	101
rs:WP_039489853	phosphoribosyl-ATP pyrophosphatase [Pectobacterium carotovorum].	44.21	95	53	0	24	118	23	117	1e-23	102
rs:WP_017373035	phosphoribosyl-AMP cyclohydrolase [Enterobacteriaceae bacterium LSJC7].	48.86	88	45	0	25	112	18	105	1e-23	101
rs:WP_022126399	phosphoribosyl-ATP diphosphatase [Bacteroides coprocola CAG:162].	44.12	102	53	1	11	112	1	98	1e-23	101
rs:WP_022551137	histidine biosynthesis protein HisIE [Vibrio nigripulchritudo].	49.44	89	45	0	24	112	22	110	1e-23	102
tr:V6AV08_9ARCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	42.55	94	54	0	24	117	15	108	1e-23	99.4
rs:WP_006714246	phosphoribosyl-AMP cyclohydrolase [Vibrio ichthyoenteri].	50.56	89	44	0	24	112	22	110	1e-23	102
rs:WP_039666413	phosphoribosyl-ATP pyrophosphatase [Campylobacter sp. RM16704].	45.56	90	49	0	23	112	18	107	1e-23	101
tr:T1AMT4_9ZZZZ	SubName: Full=Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein {ECO:0000313|EMBL:EQD43370.1};	44.44	99	55	0	20	118	1	99	1e-23	101
rs:WP_008545562	phosphoribosyl-AMP cyclohydrolase [Candidatus Pelagibacter sp. HTCC7211].	40.83	120	66	2	17	131	18	137	1e-23	100
rs:WP_039978249	phosphoribosyl-ATP pyrophosphatase [Shewanella decolorationis].	49.45	91	46	0	22	112	10	100	1e-23	101
rs:WP_041413001	phosphoribosyl-ATP pyrophosphatase [Shewanella sp. ANA-3].	49.45	91	46	0	22	112	10	100	1e-23	101
rs:WP_043059008	phosphoribosyl-AMP cyclohydrolase [Sphingomonas taxi].	47.47	99	51	1	19	117	14	111	1e-23	99.4
rs:WP_046369355	phosphoribosyl-ATP pyrophosphatase [Flavihumibacter petaseus].	49.43	87	44	0	25	111	12	98	1e-23	101
rs:WP_015897432	phosphoribosyl-AMP cyclohydrolase [Acidobacterium capsulatum].	49.45	91	44	1	24	112	13	103	1e-23	99.4
rs:WP_039532908	phosphoribosyl-ATP pyrophosphatase [Pectobacterium carotovorum].	44.21	95	53	0	24	118	23	117	1e-23	101
rs:WP_039357916	phosphoribosyl-ATP pyrophosphatase [Pectobacterium carotovorum].	44.21	95	53	0	24	118	23	117	1e-23	101
rs:WP_021793926	hypothetical protein [Thermoplasmatales archaeon A-plasma].	40.16	122	67	2	14	130	6	126	1e-23	101
rs:WP_032092327	phosphoribosyl-ATP pyrophosphatase [Necropsobacter rosorum].	44.68	94	52	0	25	118	16	109	1e-23	102
rs:WP_036898065	phosphoribosyl-ATP pyrophosphatase [Prevotella sp. S7 MS 2].	48.31	89	46	0	24	112	11	99	1e-23	101
rs:WP_039556720	phosphoribosyl-ATP pyrophosphatase [Pectobacterium carotovorum].	44.21	95	53	0	24	118	23	117	1e-23	101
rs:WP_043850848	phosphoribosyl-ATP pyrophosphatase [Aeromonas sp. L_1B5_3].	49.44	89	45	0	24	112	28	116	1e-23	102
rs:WP_041997098	phosphoribosyl-ATP pyrophosphatase [Aeromonas bivalvium].	49.44	89	45	0	24	112	23	111	1e-23	101
rs:WP_000954865	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	47.19	89	47	0	24	112	17	105	1e-23	101
rs:WP_041511044	phosphoribosyl-ATP pyrophosphatase [Shewanella sp. cp20].	48.31	89	46	0	24	112	17	105	1e-23	101
rs:WP_026729812	phosphoribosyl-ATP pyrophosphatase [Flavobacterium denitrificans].	47.73	88	46	0	24	111	10	97	1e-23	101
rs:WP_007963934	phosphoribosyl-AMP cyclohydrolase [Xanthomonas fuscans].	49.45	91	46	0	24	114	22	112	1e-23	101
rs:WP_005915380	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Xanthomonas].	49.45	91	46	0	24	114	22	112	1e-23	101
tr:A0A077SBB5_XANCA	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	49.45	91	46	0	24	114	17	107	1e-23	101
rs:WP_007647560	phosphoribosyl-AMP cyclohydrolase [Shewanella sp. HN-41].	45.71	105	51	1	14	112	10	114	1e-23	102
tr:B0TQY7_SHEHH	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	48.31	89	46	0	24	112	25	113	1e-23	101
rs:WP_044862906	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	1e-23	101
rs:WP_039112023	phosphoribosyl-ATP pyrophosphatase [Flavobacterium sp. KMS].	46.15	91	49	0	21	111	8	98	1e-23	101
rs:WP_029270233	phosphoribosyl-ATP pyrophosphatase [Flavobacterium sp. KJJ].	47.73	88	46	0	24	111	10	97	1e-23	101
rs:WP_046273467	phosphoribosyl-ATP pyrophosphatase [Stenotrophomonas maltophilia].	48.31	89	46	0	24	112	27	115	1e-23	101
rs:WP_041291262	imidazole glycerol phosphate synthase [Kytococcus sedentarius].	51.69	89	43	0	24	112	22	110	1e-23	102
rs:WP_001501314	phosphoribosyl-ATP diphosphatase [Escherichia coli].	46.07	89	48	0	24	112	17	105	1e-23	101
rs:WP_020596734	phosphoribosyl-AMP cyclohydrolase [Spirosoma panaciterrae].	43.81	105	54	1	8	112	2	101	1e-23	101
rs:WP_017220013	phosphoribosyl-AMP cyclohydrolase [Moritella dasanensis].	47.25	91	48	0	24	114	17	107	1e-23	101
rs:WP_000954860	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	46.07	89	48	0	24	112	17	105	1e-23	101
rs:WP_026997895	phosphoribosyl-ATP pyrophosphatase [Flectobacillus major].	46.94	98	52	0	22	119	8	105	1e-23	101
rs:WP_012024930	phosphoribosyl-AMP cyclohydrolase [Flavobacterium johnsoniae].	47.73	88	46	0	24	111	10	97	1e-23	101
rs:WP_006987156	phosphoribosyl-AMP cyclohydrolase [Gillisia limnaea].	46.15	91	49	0	21	111	8	98	1e-23	101
rs:WP_004965200	phosphoribosyl-AMP cyclohydrolase [Serratia odorifera].	45.74	94	51	0	25	118	18	111	1e-23	101
rs:WP_011094134	phosphoribosyl-AMP cyclohydrolase [Pectobacterium atrosepticum].	44.21	95	53	0	24	118	23	117	1e-23	101
rs:WP_033802539	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	1e-23	101
rs:WP_044706518	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	1e-23	101
rs:WP_036837446	phosphoribosyl-ATP pyrophosphatase [Photorhabdus temperata].	46.67	90	48	0	23	112	16	105	1e-23	101
rs:WP_021539189	histidine biosynthesis HisIE [Escherichia coli].	47.19	89	47	0	24	112	17	105	1e-23	101
rs:WP_043019294	phosphoribosyl-ATP pyrophosphatase [Campylobacter subantarcticus].	43.48	92	52	0	24	115	19	110	1e-23	101
rs:WP_001402311	phosphoribosyl-ATP diphosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	1e-23	101
rs:WP_008464089	phosphoribosyl-AMP cyclohydrolase [Flavobacterium sp. F52].	47.73	88	46	0	24	111	10	97	1e-23	101
rs:WP_041416334	phosphoribosyl-ATP pyrophosphatase [Shewanella halifaxensis].	48.31	89	46	0	24	112	11	99	1e-23	101
rs:WP_021326354	phosphoribosyl-AMP cyclohydrolase [Photorhabdus temperata].	46.67	90	48	0	23	112	16	105	1e-23	101
rs:WP_045802867	phosphoribosyl-ATP pyrophosphatase [Muricauda lutaonensis].	48.35	91	47	0	21	111	8	98	1e-23	101
rs:WP_025315706	phosphoribosyl-ATP pyrophosphatase [Gilliamella apicola].	43.69	103	57	1	11	112	1	103	1e-23	101
rs:WP_006320932	phosphoribosyl-AMP cyclohydrolase [Serratia plymuthica].	43.62	94	53	0	25	118	18	111	1e-23	101
rs:WP_046098460	phosphoribosyl-ATP pyrophosphatase [Avibacterium paragallinarum].	47.87	94	49	0	24	117	12	105	1e-23	101
rs:WP_026751984	phosphoribosyl-ATP pyrophosphatase [Sediminibacterium sp. C3].	44.55	101	51	1	11	111	3	98	1e-23	101
rs:WP_017158500	phosphoribosyl-AMP cyclohydrolase [Xanthomonas axonopodis].	49.45	91	46	0	24	114	22	112	1e-23	101
rs:WP_005599589	phosphoribosyl-AMP cyclohydrolase [Vibrio scophthalmi].	50.56	89	44	0	24	112	22	110	1e-23	101
rs:WP_028786860	phosphoribosyl-ATP pyrophosphatase [Terrimonas ferruginea].	46.07	89	48	0	24	112	11	99	1e-23	101
tr:A0A078KKE8_9FIRM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	53.25	77	36	0	40	116	1	77	1e-23	98.2
tr:V4R251_9CAUL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	48.48	99	51	0	21	119	25	123	1e-23	101
rs:WP_024626053	phosphoribosyl-AMP cyclohydrolase [Lactobacillus fabifermentans].	53.16	79	37	0	38	116	26	104	1e-23	99.0
rs:WP_036384760	phosphoribosyl-ATP pyrophosphatase [Muricauda sp. MAR_2010_75].	46.15	91	49	0	21	111	8	98	1e-23	101
rs:WP_038341335	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	1e-23	101
rs:WP_038237987	phosphoribosyl-ATP pyrophosphatase [Xenorhabdus szentirmaii].	48.86	88	45	0	25	112	18	105	1e-23	101
rs:WP_026934984	phosphoribosyl-ATP pyrophosphatase [Gramella echinicola].	43.96	91	51	0	21	111	8	98	1e-23	101
rs:WP_042638426	phosphoribosyl-ATP pyrophosphatase [Aeromonas eucrenophila].	49.44	89	45	0	24	112	23	111	1e-23	101
rs:WP_013783419	phosphoribosyl-AMP cyclohydrolase [Alteromonas sp. SN2].	48.89	90	46	0	24	113	18	107	1e-23	101
rs:WP_034893378	phosphoribosyl-AMP cyclohydrolase [Candidatus Accumulibacter sp. SK-11].	51.43	105	50	1	17	120	13	117	1e-23	99.8
rs:WP_026172649	imidazole glycerol phosphate synthase [Asticcacaulis benevestitus].	48.48	99	51	0	21	119	23	121	1e-23	101
rs:WP_004304029	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacteroides].	45.10	102	50	2	11	112	3	98	1e-23	101
rs:WP_038843000	phosphoribosyl-ATP pyrophosphatase [Campylobacter coli].	46.07	89	48	0	24	112	18	106	1e-23	101
tr:C2WZ90_BACCE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	53.66	82	38	0	35	116	7	88	1e-23	98.2
rs:WP_017805085	phosphoribosyl-AMP cyclohydrolase [Avibacterium paragallinarum].	47.87	94	49	0	24	117	12	105	1e-23	101
rs:WP_026977533	phosphoribosyl-ATP pyrophosphatase [Flavobacterium tegetincola].	47.25	91	48	0	24	114	10	100	1e-23	101
rs:WP_010522535	phosphoribosyl-AMP cyclohydrolase [Flavobacteriaceae bacterium HQM9].	42.57	101	55	1	11	111	1	98	1e-23	101
rs:WP_032204453	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	1e-23	101
rs:WP_028759777	phosphoribosyl-ATP pyrophosphatase [Shewanella putrefaciens].	48.00	100	51	1	14	112	10	109	1e-23	101
tr:C2UST3_BACCE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	53.66	82	38	0	35	116	6	87	1e-23	98.2
rs:WP_033071370	phosphoribosyl-ATP pyrophosphatase [Pectobacterium wasabiae].	44.21	95	53	0	24	118	23	117	1e-23	101
rs:WP_024248882	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	1e-23	101
rs:WP_017113831	phosphoribosyl-AMP cyclohydrolase [Xanthomonas campestris].	49.45	91	46	0	24	114	22	112	1e-23	101
rs:WP_003631971	phosphoribosyl-AMP cyclohydrolase [Legionella longbeachae].	48.31	89	46	0	24	112	16	104	1e-23	101
rs:WP_004942439	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Serratia].	43.62	94	53	0	25	118	18	111	1e-23	101
rs:WP_042062611	phosphoribosyl-ATP pyrophosphatase [Aeromonas allosaccharophila].	47.78	90	47	0	23	112	27	116	1e-23	101
rs:WP_002783463	phosphoribosyl-AMP cyclohydrolase [Campylobacter coli].	42.71	96	55	0	24	119	18	113	1e-23	101
rs:WP_009057067	phosphoribosyl-AMP cyclohydrolase [Nitritalea halalkaliphila].	44.94	89	49	0	24	112	13	101	1e-23	101
rs:WP_021790298	hypothetical protein [Thermoplasmatales archaeon Gpl].	40.16	122	67	2	14	130	50	170	1e-23	102
rs:WP_038336481	phosphoribosyl-ATP pyrophosphatase [Empedobacter falsenii].	37.60	125	64	2	11	126	3	122	1e-23	101
rs:WP_024870767	phosphoribosyl-ATP pyrophosphatase [Tolumonas sp. BRL6-1].	51.69	89	43	0	24	112	16	104	1e-23	101
tr:A0A0E1L8L4_ECOLX	SubName: Full=Histidine biosynthesis bifunctional: phosphoribosyl-AMP cyclohydrolase (N-terminal) phosphoribosyl-ATP pyrophosphatase (C-terminal) {ECO:0000313|EMBL:AJE56564.1}; EC=3.5.4.19 {ECO:0000313|EMBL:AJE56564.1};	47.13	87	46	0	26	112	1	87	1e-23	100
rs:WP_008634650	phosphoribosyl-AMP cyclohydrolase [Bizionia argentinensis].	43.30	97	53	1	17	111	2	98	2e-23	101
tr:A0A075FMY5_9ARCH	SubName: Full=Phosphoribosyl-AMP cyclohydrolase (HisIE) {ECO:0000313|EMBL:AIE92769.1}; EC=3.5.4.19 {ECO:0000313|EMBL:AIE92769.1};	39.82	113	60	2	2	114	1	105	2e-23	98.6
rs:WP_025799890	phosphoribosyl-ATP pyrophosphatase [Prevotella saccharolytica].	40.62	128	61	2	11	127	1	124	2e-23	101
rs:WP_018710345	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacteroides].	47.19	89	47	0	24	112	10	98	2e-23	101
rs:WP_004311502	phosphoribosyl-AMP cyclohydrolase [Bacteroides ovatus].	45.54	101	49	2	11	111	3	97	2e-23	101
rs:WP_025385367	phosphoribosyl-ATP pyrophosphatase [Legionella oakridgensis].	50.56	89	44	0	24	112	16	104	2e-23	101
rs:WP_009102442	phosphoribosyl-ATP diphosphatase [Treponema sp. JC4].	46.09	115	58	2	16	130	242	352	2e-23	103
rs:WP_042905451	phosphoribosyl-ATP pyrophosphatase [Haemophilus parasuis].	46.67	90	48	0	24	113	12	101	2e-23	101
rs:WP_017155311	phosphoribosyl-AMP cyclohydrolase [Xanthomonas axonopodis].	49.45	91	46	0	24	114	22	112	2e-23	101
tr:X2H141_9GAMM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	41.28	109	63	1	5	112	7	115	2e-23	101
rs:WP_002779534	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Campylobacter].	42.71	96	55	0	24	119	18	113	2e-23	101
rs:WP_022510669	phosphoribosyl-ATP diphosphatase [Prevotella sp. CAG:617].	50.56	89	44	0	24	112	15	103	2e-23	101
rs:WP_038832646	phosphoribosyl-ATP pyrophosphatase [Campylobacter coli].	46.07	89	48	0	24	112	18	106	2e-23	101
rs:WP_046557464	phosphoribosyl-ATP pyrophosphatase [Arsukibacterium ikkense].	40.71	113	64	1	18	130	9	118	2e-23	101
rs:WP_038355112	phosphoribosyl-ATP pyrophosphatase [Escherichia sp. HT073016].	47.19	89	47	0	24	112	17	105	2e-23	101
rs:WP_034612524	phosphoribosyl-ATP pyrophosphatase [Chelonobacter oris].	47.78	90	47	0	24	113	11	100	2e-23	101
rs:WP_008296451	phosphoribosyl-ATP pyrophosphatase [Bhargavaea cecembensis].	48.31	89	46	0	24	112	8	96	2e-23	101
rs:WP_002808456	phosphoribosyl-AMP cyclohydrolase [Campylobacter coli].	46.07	89	48	0	24	112	18	106	2e-23	101
rs:WP_002788583	phosphoribosyl-AMP cyclohydrolase [Campylobacter coli].	46.07	89	48	0	24	112	18	106	2e-23	101
rs:WP_020974188	phosphoribosyl-AMP cyclohydrolase [Campylobacter coli].	46.07	89	48	0	24	112	18	106	2e-23	101
rs:WP_026259962	phosphoribosyl-ATP pyrophosphatase [Segetibacter koreensis].	46.07	89	48	0	24	112	11	99	2e-23	100
rs:WP_042655749	phosphoribosyl-ATP pyrophosphatase [Aeromonas allosaccharophila].	49.44	89	45	0	24	112	28	116	2e-23	101
rs:WP_042965251	phosphoribosyl-ATP pyrophosphatase [Campylobacter coli].	46.07	89	48	0	24	112	18	106	2e-23	101
rs:WP_008571447	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Xanthomonas].	49.45	91	46	0	24	114	22	112	2e-23	101
rs:WP_047124287	phosphoribosyl-ATP pyrophosphatase [Xanthomonas arboricola].	48.35	91	47	0	24	114	22	112	2e-23	101
rs:WP_044513616	phosphoribosyl-ATP pyrophosphatase [Hymenobacter sp. DG25B].	50.00	92	46	0	24	115	9	100	2e-23	101
tr:L1NK06_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	41.04	134	62	3	5	127	2	129	2e-23	101
rs:WP_000954918	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	47.19	89	47	0	24	112	17	105	2e-23	100
rs:WP_038191807	phosphoribosyl-ATP pyrophosphatase [Xenorhabdus bovienii].	47.73	88	46	0	25	112	18	105	2e-23	101
rs:WP_009598312	phosphoribosyl-AMP cyclohydrolase [Alistipes sp. HGB5].	49.44	89	45	0	24	112	19	107	2e-23	101
rs:WP_027271650	phosphoribosyl-ATP pyrophosphatase [Legionella sainthelensi].	48.31	89	46	0	24	112	16	104	2e-23	101
rs:WP_038830984	phosphoribosyl-ATP pyrophosphatase [Campylobacter coli].	46.07	89	48	0	24	112	18	106	2e-23	101
rs:WP_040069804	phosphoribosyl-ATP pyrophosphatase [Aeromonas veronii].	49.44	89	45	0	24	112	23	111	2e-23	101
rs:WP_038259481	phosphoribosyl-ATP pyrophosphatase [Xenorhabdus cabanillasii].	48.31	89	46	0	24	112	22	110	2e-23	101
rs:WP_039667852	phosphoribosyl-ATP pyrophosphatase [Campylobacter lari].	44.57	92	51	0	24	115	19	110	2e-23	101
rs:WP_041409033	phosphoribosyl-ATP pyrophosphatase [Shewanella sp. MR-4].	49.45	91	46	0	22	112	10	100	2e-23	100
rs:WP_016777865	phosphoribosyl-AMP cyclohydrolase [Anaerophaga thermohalophila].	46.07	89	48	0	24	112	11	99	2e-23	100
rs:WP_002814766	phosphoribosyl-AMP cyclohydrolase [Campylobacter coli].	42.71	96	55	0	24	119	18	113	2e-23	101
rs:WP_037394094	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Serratia].	43.16	95	54	0	24	118	17	111	2e-23	100
rs:WP_046745546	phosphoribosyl-ATP pyrophosphatase [Kordia sp. MCCC 1A00726].	46.59	88	47	0	24	111	11	98	2e-23	100
rs:WP_046756827	phosphoribosyl-ATP pyrophosphatase [Kordia jejudonensis].	46.15	91	49	0	21	111	8	98	2e-23	100
rs:WP_033640857	phosphoribosyl-ATP pyrophosphatase [Serratia marcescens].	44.21	95	53	0	24	118	17	111	2e-23	100
tr:A0KWA9_SHESA	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	49.45	91	46	0	22	112	27	117	2e-23	101
rs:WP_014084174	phosphoribosyl-AMP cyclohydrolase [Flavobacterium branchiophilum].	47.73	88	46	0	24	111	11	98	2e-23	100
rs:WP_026110273	phosphoribosyl-ATP pyrophosphatase [gamma proteobacterium WG36].	43.16	95	54	0	24	118	17	111	2e-23	100
rs:WP_000954925	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	47.19	89	47	0	24	112	17	105	2e-23	100
rs:WP_012155695	phosphoribosyl-AMP cyclohydrolase [Shewanella pealeana].	48.31	89	46	0	24	112	24	112	2e-23	101
rs:WP_014776362	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Alistipes].	49.44	89	45	0	24	112	19	107	2e-23	100
rs:WP_033093467	phosphoribosyl-ATP pyrophosphatase [Colwellia psychrerythraea].	47.19	89	47	0	24	112	18	106	2e-23	100
rs:WP_000954926	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	47.19	89	47	0	24	112	17	105	2e-23	100
rs:WP_011637179	phosphoribosyl-AMP cyclohydrolase [Shewanella frigidimarina].	42.86	105	59	1	9	112	2	106	2e-23	100
rs:WP_022686531	phosphoribosyl-AMP cyclohydrolase [Sphingomonas phyllosphaerae].	46.23	106	56	1	19	123	14	119	2e-23	99.0
gpu:CP010423_2039	phosphoribosyl-ATP pyrophosphatase [Pragia fontium]	46.07	89	48	0	24	112	17	105	2e-23	100
rs:WP_029819272	phosphoribosyl-ATP pyrophosphatase [Xanthomonas alfalfae].	49.45	91	46	0	24	114	22	112	2e-23	100
tr:V1DC31_9GAMM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	49.45	91	46	0	22	112	27	117	2e-23	101
rs:WP_019946706	hypothetical protein [Hymenobacter aerophilus].	51.69	89	43	0	24	112	9	97	2e-23	101
rs:WP_024084071	phosphoribosyl-AMP cyclohydrolase [Sulfolobus acidocaldarius].	50.00	88	44	0	26	113	24	111	2e-23	98.6
rs:WP_009359979	phosphoribosyl-AMP cyclohydrolase [alpha proteobacterium HIMB114].	48.96	96	48	1	19	113	20	115	2e-23	99.8
rs:WP_028378290	phosphoribosyl-ATP pyrophosphatase [Legionella pneumophila].	43.64	110	56	2	12	115	3	112	2e-23	100
rs:WP_021646267	phosphoribosyl-ATP diphosphatase [Bacteroides pyogenes].	44.12	102	51	2	11	112	2	97	2e-23	100
rs:WP_013736940	phosphoribosyl-AMP cyclohydrolase [Metallosphaera cuprina].	47.31	93	49	0	21	113	19	111	2e-23	98.6
rs:WP_011626320	phosphoribosyl-AMP cyclohydrolase [Shewanella sp. MR-7].	49.45	91	46	0	22	112	27	117	2e-23	101
rs:WP_027384807	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium caeni].	43.30	97	54	1	17	112	2	98	2e-23	100
rs:WP_022102808	phosphoribosyl-ATP diphosphatase [Prevotella sp. CAG:5226].	45.45	99	54	0	24	122	17	115	2e-23	100
tr:C2YP34_BACCE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	54.43	79	36	0	35	113	5	83	2e-23	97.8
rs:WP_024245838	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	47.19	89	47	0	24	112	17	105	2e-23	100
rs:WP_041063229	phosphoribosyl-ATP pyrophosphatase [symbiont bacterium UwTKB of Urostylis westwoodii].	42.99	107	56	1	24	125	17	123	2e-23	100
rs:WP_027071623	hypothetical protein [Luteimonas sp. J29].	48.48	99	50	1	17	114	11	109	2e-23	100
rs:WP_011866002	phosphoribosyl-AMP cyclohydrolase [Shewanella loihica].	47.19	89	47	0	24	112	17	105	2e-23	100
rs:WP_007748067	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacteroides].	46.07	89	48	0	24	112	10	98	2e-23	100
rs:WP_037322462	phosphoribosyl-ATP pyrophosphatase [Salegentibacter sp. Hel_I_6].	46.15	91	49	0	21	111	8	98	2e-23	100
rs:WP_012208846	phosphoribosyl-ATP pyrophosphatase [Petrotoga mobilis].	50.56	89	43	1	24	112	18	105	2e-23	101
rs:WP_021533031	histidine biosynthesis HisIE [Escherichia coli].	47.19	89	47	0	24	112	17	105	2e-23	100
rs:WP_019030027	phosphoribosyl-AMP cyclohydrolase [Colwellia piezophila].	47.19	89	47	0	24	112	18	106	2e-23	100
rs:WP_014610464	phosphoribosyl-AMP cyclohydrolase [Shewanella putrefaciens].	48.00	100	51	1	14	112	10	109	2e-23	100
rs:WP_022232576	phosphoribosyl-ATP diphosphatase [Bacteroides sp. CAG:443].	45.10	102	50	2	11	112	3	98	2e-23	100
rs:WP_007561805	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacteroides].	47.19	89	47	0	24	112	10	98	2e-23	100
tr:A0A061RVD8_9CHLO	SubName: Full=Phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:JAC76842.1}; Flags: Fragment;	48.00	100	52	0	17	116	67	166	2e-23	102
rs:WP_021557903	histidine biosynthesis HisIE [Escherichia coli].	47.19	89	47	0	24	112	17	105	2e-23	100
rs:WP_011213546	phosphoribosyl-AMP cyclohydrolase [Legionella pneumophila].	43.64	110	56	2	12	115	3	112	2e-23	100
rs:WP_041211395	phosphoribosyl-ATP pyrophosphatase [Aeromonas caviae].	48.31	89	46	0	24	112	23	111	2e-23	100
rs:WP_027265734	phosphoribosyl-ATP pyrophosphatase [Legionella pneumophila].	43.64	110	56	2	12	115	3	112	2e-23	100
rs:WP_044063757	phosphoribosyl-ATP pyrophosphatase [Prevotella saccharolytica].	40.62	128	61	2	11	127	1	124	2e-23	100
rs:WP_024993497	phosphoribosyl-ATP pyrophosphatase [Bacteroides paurosaccharolyticus].	47.19	89	47	0	24	112	10	98	2e-23	100
tr:C7LZ79_ACIFD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00006950}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021, ECO:0000256|SAAS:SAAS00103216};	45.54	112	57	3	2	112	4	112	2e-23	98.6
rs:WP_036850878	phosphoribosyl-ATP pyrophosphatase [Photorhabdus temperata].	46.67	90	48	0	23	112	16	105	2e-23	100
rs:WP_010946926	phosphoribosyl-AMP cyclohydrolase [Legionella pneumophila].	43.64	110	56	2	12	115	3	112	2e-23	100
rs:WP_029454449	phosphoribosyl-AMP cyclohydrolase [Candidatus Pelagibacter ubique].	41.88	117	63	2	17	128	18	134	2e-23	99.4
rs:WP_014841425	phosphoribosyl-AMP cyclohydrolase [Legionella pneumophila].	43.64	110	56	2	12	115	3	112	2e-23	100
rs:WP_027272967	phosphoribosyl-ATP pyrophosphatase [Leminorella grimontii].	48.31	89	46	0	24	112	20	108	2e-23	100
tr:A0A087RS87_9ARCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	41.75	103	54	1	11	113	8	104	2e-23	98.2
rs:WP_011215294	phosphoribosyl-AMP cyclohydrolase [Legionella pneumophila].	43.64	110	56	2	12	115	3	112	2e-23	100
rs:WP_011789156	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Shewanella].	48.00	100	51	1	14	112	10	109	3e-23	100
rs:WP_011946301	phosphoribosyl-AMP cyclohydrolase [Legionella pneumophila].	43.64	110	56	2	12	115	3	112	3e-23	100
rs:WP_038263866	phosphoribosyl-ATP pyrophosphatase [Zhouia amylolytica].	45.05	91	50	0	21	111	8	98	3e-23	100
tr:A0A078LC69_CITKO	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	42.48	113	55	1	24	126	17	129	3e-23	100
rs:WP_016999077	hypothetical protein [Staphylococcus lentus].	43.96	91	51	0	24	114	11	101	3e-23	100
rs:WP_027220745	phosphoribosyl-ATP pyrophosphatase [Legionella pneumophila].	43.64	110	56	2	12	115	3	112	3e-23	100
rs:WP_029455388	phosphoribosyl-AMP cyclohydrolase [Candidatus Pelagibacter ubique].	40.83	120	66	2	17	131	18	137	3e-23	99.4
rs:WP_036938223	phosphoribosyl-ATP pyrophosphatase [Proteus vulgaris].	46.07	89	48	0	24	112	17	105	3e-23	100
rs:WP_038219815	phosphoribosyl-ATP pyrophosphatase [Xenorhabdus nematophila].	48.31	89	46	0	24	112	22	110	3e-23	100
rs:WP_028384144	phosphoribosyl-ATP pyrophosphatase [Legionella moravica].	48.31	89	46	0	24	112	16	104	3e-23	100
rs:WP_005352195	phosphoribosyl-AMP cyclohydrolase [Aeromonas veronii].	47.78	90	47	0	24	113	28	117	3e-23	100
rs:WP_021185952	phosphoribosyl-AMP cyclohydrolase [Pantoea sp. AS-PWVM4].	44.79	96	53	0	23	118	16	111	3e-23	100
rs:WP_007809216	phosphoribosyl-AMP cyclohydrolase [Flavobacterium sp. CF136].	47.73	88	46	0	24	111	11	98	3e-23	100
rs:WP_011731769	phosphoribosyl-ATP pyrophosphatase [Campylobacter fetus].	46.32	95	50	1	23	116	9	103	3e-23	101
rs:WP_027226754	phosphoribosyl-ATP pyrophosphatase [Legionella pneumophila].	43.64	110	56	2	12	115	3	112	3e-23	100
gpu:CP011125_5294	Phosphoribosyl-AMP cyclohydrolase [Sandaracinus amylolyticus]	41.38	116	68	0	13	128	1	116	3e-23	100
rs:WP_015674524	phosphoribosyl-AMP cyclohydrolase [Actinobacillus suis].	47.19	89	47	0	25	113	13	101	3e-23	100
rs:WP_012660855	phosphoribosyl-AMP cyclohydrolase [Campylobacter lari].	44.57	92	51	0	24	115	19	110	3e-23	100
rs:WP_027221433	phosphoribosyl-ATP pyrophosphatase [Legionella pneumophila].	43.64	110	56	2	12	115	3	112	3e-23	100
tr:A0A094VWJ9_PROVU	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	46.07	89	48	0	24	112	16	104	3e-23	100
rs:WP_035635191	phosphoribosyl-ATP pyrophosphatase [Flavobacterium sp. EM1308].	47.73	88	46	0	24	111	10	97	3e-23	100
rs:WP_001578574	histidine biosynthesis HisIE [Escherichia coli].	47.19	89	47	0	24	112	17	105	3e-23	100
rs:WP_038452797	phosphoribosyl-ATP diphosphatase [Campylobacter fetus].	46.32	95	50	1	23	116	9	103	3e-23	101
tr:A0A087S330_9ARCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	40.38	104	56	1	11	114	8	105	3e-23	97.8
rs:WP_019001567	hypothetical protein [Succinimonas amylolytica].	37.50	128	78	2	6	131	2	129	3e-23	99.8
rs:WP_003757968	phosphoribosyl-AMP cyclohydrolase [Listeria grayi].	44.00	100	56	0	24	123	11	110	3e-23	98.2
rs:WP_016848639	phosphoribosyl-AMP cyclohydrolase [Xanthomonas axonopodis].	48.35	91	47	0	24	114	22	112	3e-23	100
rs:WP_046243048	phosphoribosyl-ATP pyrophosphatase [Hymenobacter sp. MIMtkLc17].	45.36	97	52	1	17	112	2	98	3e-23	100
rs:WP_032342908	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	46.07	89	48	0	24	112	17	105	3e-23	100
rs:WP_005678109	phosphoribosyl-AMP cyclohydrolase [Bacteroides caccae].	46.07	89	48	0	24	112	10	98	3e-23	100
rs:WP_019440275	phosphoribosyl-AMP cyclohydrolase [Moritella marina].	47.25	91	48	0	24	114	17	107	3e-23	100
rs:WP_024495522	phosphoribosyl-ATP pyrophosphatase [Candidatus Schmidhempelia bombi].	45.74	94	51	0	25	118	15	108	3e-23	100
rs:WP_028037181	phosphoribosyl-AMP cyclohydrolase [Candidatus Pelagibacter ubique].	41.67	120	65	2	17	131	18	137	3e-23	99.0
sp:HIS3_NITMS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	41.35	104	55	1	11	114	8	105	3e-23	97.8
gp:CP000446_1785	phosphoribosyl-ATP pyrophosphatase / phosphoribosyl-AMP cyclohydrolase [Shewanella sp. MR-4]	49.45	91	46	0	22	112	27	117	3e-23	100
rs:WP_014511583	phosphoribosyl-AMP cyclohydrolase [Sulfolobus solfataricus].	44.44	99	54	1	16	113	11	109	3e-23	98.2
rs:WP_042043204	phosphoribosyl-ATP pyrophosphatase [Aeromonas rivuli].	46.07	89	48	0	24	112	21	109	3e-23	100
rs:WP_002781413	phosphoribosyl-AMP cyclohydrolase [Campylobacter coli].	43.16	95	54	0	25	119	19	113	3e-23	100
rs:WP_039119163	phosphoribosyl-ATP pyrophosphatase [Flavobacterium sp. JRM].	45.05	91	50	0	21	111	8	98	3e-23	100
rs:WP_011846974	phosphoribosyl-AMP cyclohydrolase [Shewanella baltica].	49.44	89	45	0	24	112	21	109	3e-23	100
rs:WP_020527973	hypothetical protein [Flexithrix dorotheae].	43.40	106	53	2	23	121	20	125	3e-23	98.6
rs:WP_012089368	phosphoribosyl-AMP cyclohydrolase [Shewanella baltica].	49.44	89	45	0	24	112	21	109	3e-23	100
rs:WP_011258948	phosphoribosyl-AMP cyclohydrolase [Xanthomonas oryzae].	48.35	91	47	0	24	114	22	112	3e-23	100
rs:WP_045958965	phosphoribosyl-ATP pyrophosphatase [Xenorhabdus poinarii].	48.31	89	46	0	24	112	22	110	3e-23	100
rs:WP_039172882	phosphoribosyl-ATP pyrophosphatase [Gallibacterium genomosp. 1].	46.81	94	50	0	24	117	17	110	3e-23	100
rs:WP_031530830	phosphoribosyl-ATP pyrophosphatase [Dyadobacter crusticola].	45.19	104	52	1	9	112	6	104	3e-23	100
rs:WP_023384340	phosphoribosyl-AMP cyclohydrolase [Campylobacter fetus].	46.32	95	50	1	23	116	9	103	3e-23	100
rs:WP_016438561	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Coprococcus].	44.76	105	56	1	9	113	222	324	4e-23	102
tr:A0A075HMD2_9ARCH	SubName: Full=Phosphoribosyl-AMP cyclohydrolase (HisIE) {ECO:0000313|EMBL:AIF15597.1}; EC=3.5.4.19 {ECO:0000313|EMBL:AIF15597.1};	42.86	91	52	0	24	114	15	105	4e-23	97.8
rs:WP_024745438	phosphoribosyl-ATP pyrophosphatase [Xanthomonas oryzae].	48.35	91	47	0	24	114	22	112	4e-23	100
sp:HIS2_XANCP	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	46.30	108	53	2	8	114	9	112	4e-23	100
rs:WP_019302511	phosphoribosyl-AMP cyclohydrolase [Xanthomonas oryzae].	48.35	91	47	0	24	114	22	112	4e-23	100
rs:WP_005618468	phosphoribosyl-AMP cyclohydrolase [Actinobacillus pleuropneumoniae].	47.19	89	47	0	25	113	14	102	4e-23	100
rs:WP_007769127	phosphoribosyl-AMP cyclohydrolase [Siccibacter turicensis].	47.19	89	47	0	24	112	17	105	4e-23	100
rs:WP_043877986	phosphoribosyl-ATP pyrophosphatase [Actinobacillus pleuropneumoniae].	47.19	89	47	0	25	113	12	100	4e-23	100
rs:WP_020568773	hypothetical protein [Lewinella persica].	47.92	96	48	1	18	111	11	106	4e-23	100
rs:WP_015741764	phosphoribosyl-AMP cyclohydrolase [Cronobacter turicensis].	47.19	89	47	0	24	112	17	105	4e-23	100
rs:WP_011044644	phosphoribosyl-AMP cyclohydrolase [Colwellia psychrerythraea].	47.19	89	47	0	24	112	18	106	4e-23	100
rs:WP_035349527	phosphoribosyl-AMP cyclohydrolase [Edaphobacter aggregans].	46.00	100	52	1	24	121	14	113	4e-23	97.8
rs:WP_033543268	phosphoribosyl-ATP pyrophosphatase [Planococcus sp. CAU13].	45.26	95	52	0	18	112	4	98	4e-23	100
tr:A0A090RD13_9VIBR	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	47.19	89	47	0	24	112	22	110	4e-23	100
rs:WP_023906331	phosphoribosyl-AMP cyclohydrolase [Xylella fastidiosa].	51.69	89	43	0	24	112	22	110	4e-23	100
sp:HIS2_XYLFA	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	51.69	89	43	0	24	112	22	110	4e-23	100
rs:WP_018627391	phosphoribosyl-AMP cyclohydrolase [Niabella aurantiaca].	48.91	92	47	0	24	115	10	101	4e-23	100
rs:WP_012021877	phosphoribosyl-AMP cyclohydrolase [Metallosphaera sedula].	47.83	92	48	0	22	113	20	111	4e-23	98.2
rs:WP_039610372	phosphoribosyl-ATP pyrophosphatase [Pseudoalteromonas luteoviolacea].	41.67	108	58	1	14	121	7	109	4e-23	100
rs:WP_007681756	phosphoribosyl-AMP cyclohydrolase [Cronobacter condimenti].	47.19	89	47	0	24	112	17	105	4e-23	100
rs:WP_009183991	phosphoribosyl-AMP cyclohydrolase [Cecembia lonarensis].	46.67	90	48	0	23	112	12	101	4e-23	100
rs:WP_042593310	histidine biosynthesis bifunctional protein HisIE [Haemophilus influenzae].	42.42	99	57	0	24	122	13	111	4e-23	100
rs:WP_022971527	phosphoribosyl-AMP cyclohydrolase [Xanthomonas sp. M97].	49.44	89	45	0	24	112	22	110	4e-23	100
rs:WP_024710660	phosphoribosyl-ATP pyrophosphatase [Xanthomonas oryzae].	48.35	91	47	0	24	114	22	112	4e-23	100
rs:WP_043901981	phosphoribosyl-ATP pyrophosphatase [Pectobacterium carotovorum].	43.62	94	53	0	25	118	1	94	4e-23	99.8
rs:WP_014507577	phosphoribosyl-AMP cyclohydrolase [Xanthomonas campestris].	46.30	108	53	2	8	114	9	112	4e-23	100
rs:WP_020707545	hypothetical protein [Acidobacteriaceae bacterium KBS 83].	49.00	100	48	2	16	112	9	108	4e-23	98.2
tr:D9PBD0_ACTPL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	47.19	89	47	0	25	113	14	102	4e-23	100
rs:WP_043991987	phosphoribosyl-ATP pyrophosphatase [Actinobacillus pleuropneumoniae].	47.19	89	47	0	25	113	12	100	4e-23	100
rs:WP_012438267	phosphoribosyl-AMP cyclohydrolase [Xanthomonas campestris].	46.30	108	53	2	8	114	9	112	4e-23	100
tr:A0A090PLB4_9VIBR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	53.01	83	39	0	24	106	22	104	4e-23	99.4
rs:WP_023397781	phosphoribosyl-ATP pyrophosphohydrolase [Pseudoalteromonas luteoviolacea].	44.44	99	55	0	14	112	7	105	4e-23	100
rs:WP_039344616	phosphoribosyl-ATP pyrophosphatase [Pectobacterium carotovorum].	43.16	95	54	0	24	118	23	117	4e-23	100
rs:WP_010277161	phosphoribosyl-AMP cyclohydrolase [Pectobacterium carotovorum].	43.16	95	54	0	24	118	23	117	4e-23	100
rs:WP_041183242	phosphoribosyl-ATP pyrophosphatase [Xanthomonas oryzae].	48.35	91	47	0	24	114	22	112	4e-23	100
sp:HIS2_XYLFT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	51.69	89	43	0	24	112	22	110	4e-23	100
rs:WP_038210210	phosphoribosyl-ATP pyrophosphatase [Xylella fastidiosa].	51.69	89	43	0	24	112	22	110	4e-23	100
rs:WP_045110493	phosphoribosyl-ATP pyrophosphatase [Moritella viscosa].	47.25	91	48	0	24	114	17	107	4e-23	100
tr:G7TE34_XANOB	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	48.35	91	47	0	24	114	17	107	4e-23	100
rs:WP_042598966	phosphoribosyl-ATP pyrophosphatase [Xanthomonas campestris].	46.30	108	53	2	8	114	9	112	4e-23	100
rs:WP_003008199	phosphoribosyl-AMP cyclohydrolase [Sphingobacterium spiritivorum].	46.94	98	51	1	18	114	2	99	4e-23	99.8
rs:WP_016681698	phosphoribosyl-AMP cyclohydrolase, partial [Yersinia pestis].	48.84	86	44	0	25	110	18	103	4e-23	97.4
rs:WP_043878173	phosphoribosyl-ATP pyrophosphatase [Pectobacterium atrosepticum].	43.62	94	53	0	25	118	1	94	4e-23	99.8
rs:XP_003078643	putative phosphoribosyl-ATP pyrophosphohydrolase At-IE (ISS) [Ostreococcus tauri].	44.86	107	57	1	16	120	25	131	4e-23	102
rs:WP_012006042	phosphoribosyl-AMP cyclohydrolase [Serratia proteamaculans].	43.62	94	53	0	25	118	18	111	4e-23	100
tr:C0B1R3_9ENTR	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	44.94	89	49	0	24	112	16	104	5e-23	100
rs:WP_028770248	hypothetical protein [Silanimonas lenta].	47.52	101	52	1	13	112	2	102	5e-23	100
rs:WP_012868977	phosphoribosyl-ATP pyrophosphatase [Thermanaerovibrio acidaminovorans].	41.75	103	60	0	15	117	2	104	5e-23	100
rs:WP_014699663	phosphoribosyl-AMP cyclohydrolase [Pectobacterium wasabiae].	43.16	95	54	0	24	118	23	117	5e-23	100
tr:K0DBN7_LEUCJ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	43.69	103	55	1	17	116	4	106	5e-23	98.2
rs:WP_036774285	phosphoribosyl-ATP pyrophosphatase [Photorhabdus asymbiotica].	45.45	88	48	0	25	112	18	105	5e-23	99.8
rs:WP_041497357	phosphoribosyl-ATP pyrophosphatase [Nonlabens marinus].	43.96	91	51	0	22	112	9	99	5e-23	100
rs:WP_041773141	phosphoribosyl-AMP cyclohydrolase [Leuconostoc carnosum].	43.69	103	55	1	17	116	5	107	5e-23	98.2
rs:WP_006081895	phosphoribosyl-AMP cyclohydrolase [Shewanella baltica].	48.31	89	46	0	24	112	21	109	5e-23	100
rs:WP_006033698	phosphoribosyl-AMP cyclohydrolase [Moritella sp. PE36].	47.25	91	48	0	24	114	17	107	5e-23	99.8
rs:WP_040227273	phosphoribosyl-ATP pyrophosphatase [Bhargavaea cecembensis].	48.31	89	46	0	24	112	8	96	5e-23	99.8
rs:WP_023907511	phosphoribosyl-AMP cyclohydrolase [Xylella fastidiosa].	51.69	89	43	0	24	112	22	110	5e-23	99.8
rs:WP_010361914	phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas citrea].	46.32	95	51	0	18	112	11	105	5e-23	99.8
rs:WP_014388475	phosphoribosyl-AMP cyclohydrolase [Flavobacterium indicum].	46.15	91	49	0	21	111	8	98	5e-23	99.8
tr:C6DF70_PECCP	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	43.16	95	54	0	24	118	23	117	5e-23	99.8
rs:WP_042655095	phosphoribosyl-ATP pyrophosphatase [Actinobacillus pleuropneumoniae].	47.19	89	47	0	25	113	12	100	5e-23	100
rs:WP_028072467	phosphoribosyl-ATP pyrophosphatase [Sphingobacterium thalpophilum].	47.25	91	48	0	24	114	9	99	5e-23	99.8
tr:E0FDY1_ACTPL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	47.19	89	47	0	25	113	14	102	5e-23	100
rs:WP_039709461	phosphoribosyl-ATP pyrophosphatase [Actinobacillus pleuropneumoniae].	47.19	89	47	0	25	113	13	101	5e-23	100
rs:WP_010179432	phosphoribosyl-AMP cyclohydrolase [Aquimarina agarilytica].	45.05	91	50	0	21	111	8	98	6e-23	99.8
rs:WP_019168442	phosphoribosyl-AMP cyclohydrolase [Staphylococcus intermedius].	47.25	91	48	0	24	114	10	100	6e-23	99.8
rs:WP_013183893	phosphoribosyl-AMP cyclohydrolase [Xenorhabdus nematophila].	48.31	89	46	0	24	112	22	110	6e-23	99.8
tr:A0A076LFZ7_9EURY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	49.00	100	50	1	25	124	22	120	6e-23	97.8
rs:WP_017892207	phosphoribosyl-AMP cyclohydrolase [Serratia sp. S4].	43.62	94	53	0	25	118	18	111	6e-23	99.8
rs:WP_046420489	phosphoribosyl-ATP pyrophosphatase [Xylella fastidiosa].	51.69	89	43	0	24	112	22	110	6e-23	99.8
rs:WP_021892602	histidine biosynthesis HisIE [Bacteroides sp. CAG:20].	42.98	114	64	1	11	123	1	114	6e-23	99.8
rs:WP_002997165	phosphoribosyl-AMP cyclohydrolase [Sphingobacterium spiritivorum].	45.92	98	52	1	18	114	2	99	6e-23	99.4
rs:WP_002702879	phosphoribosyl-ATP diphosphatase [Treponema saccharophilum].	48.89	90	45	1	23	112	249	337	6e-23	102
rs:WP_044601010	phosphoribosyl-ATP pyrophosphatase [Campylobacter coli].	44.94	89	49	0	24	112	18	106	6e-23	99.8
rs:WP_023854116	phosphoribosyl-AMP cyclohydrolase [Candidatus Pelagibacter ubique].	43.81	105	58	1	17	120	18	122	6e-23	98.6
rs:WP_002824938	phosphoribosyl-AMP cyclohydrolase [Campylobacter coli].	44.94	89	49	0	24	112	18	106	6e-23	99.8
rs:WP_034913042	phosphoribosyl-ATP pyrophosphatase [Gilliamella apicola].	46.07	89	48	0	24	112	22	110	6e-23	99.8
rs:WP_033539247	phosphoribosyl-ATP pyrophosphatase [Shewanella sp. ECSMB14101].	44.55	101	55	1	12	112	6	105	6e-23	99.8
rs:WP_004388504	phosphoribosyl-AMP cyclohydrolase [Cronobacter sakazakii].	46.07	89	48	0	24	112	17	105	6e-23	99.8
rs:WP_010367158	phosphoribosyl-AMP cyclohydrolase [Xanthomonas vasicola].	48.35	91	47	0	24	114	22	112	6e-23	99.8
sp:HIS2_HELHP	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	43.96	91	51	0	25	115	15	105	6e-23	100
rs:WP_039664959	phosphoribosyl-ATP pyrophosphatase [Campylobacter volucris].	43.33	90	51	0	23	112	18	107	6e-23	99.8
rs:WP_010653968	phosphoribosyl-AMP cyclohydrolase [Fluoribacter dumoffii].	47.19	89	47	0	24	112	16	104	6e-23	99.8
rs:WP_034365560	phosphoribosyl-ATP diphosphatase [Helicobacter sp. MIT 03-1614].	43.96	91	51	0	25	115	15	105	6e-23	100
rs:WP_038507574	hypothetical protein, partial [Leptospirillum ferriphilum].	47.31	93	49	0	20	112	15	107	6e-23	99.8
rs:WP_032108464	phosphoribosyl-ATP pyrophosphatase [Haemophilus sp. FF7].	42.20	109	62	1	11	118	1	109	6e-23	99.8
rs:WP_045176212	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	47.19	89	47	0	24	112	13	101	6e-23	99.4
rs:WP_043991010	phosphoribosyl-ATP pyrophosphatase [Actinobacillus pleuropneumoniae].	47.19	89	47	0	25	113	12	100	6e-23	99.8
rs:WP_014499269	phosphoribosyl-AMP cyclohydrolase [Buchnera aphidicola].	43.96	91	51	0	24	114	17	107	6e-23	99.4
rs:WP_010538618	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Bacteroides].	44.12	102	51	2	11	112	3	98	7e-23	99.4
rs:WP_009262027	imidazole glycerol phosphate synthase [Lachnospiraceae bacterium 9_1_43BFAA].	44.76	105	56	1	9	113	222	324	7e-23	102
rs:WP_038870814	phosphoribosyl-ATP pyrophosphatase [Cronobacter dublinensis].	46.07	89	48	0	24	112	17	105	7e-23	99.4
rs:WP_007093686	phosphoribosyl-AMP cyclohydrolase [Kordia algicida].	45.98	87	47	0	25	111	12	98	7e-23	99.4
tr:E0FDW1_ACTPL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	47.19	89	47	0	25	113	14	102	7e-23	99.8
rs:WP_034687490	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium piperi].	43.14	102	52	1	11	112	3	98	7e-23	99.4
rs:WP_043948009	phosphoribosyl-ATP pyrophosphatase [Actinobacillus pleuropneumoniae].	47.19	89	47	0	25	113	12	100	7e-23	99.8
tr:B0BU56_ACTPJ	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	47.19	89	47	0	25	113	14	102	7e-23	99.8
rs:WP_044598142	phosphoribosyl-ATP pyrophosphatase [Campylobacter peloridis].	43.96	91	51	0	25	115	20	110	7e-23	99.8
rs:WP_018652623	phosphoribosyl-AMP cyclohydrolase [Actinobacillus capsulatus].	47.19	89	47	0	25	113	13	101	7e-23	99.8
rs:WP_045095218	phosphoribosyl-ATP pyrophosphatase [Legionella fallonii].	42.16	102	58	1	12	112	3	104	7e-23	99.4
rs:WP_016426040	phosphoribosyl-ATP diphosphatase [Staphylococcus sp. HGB0015].	45.05	91	50	0	24	114	10	100	7e-23	99.8
rs:WP_023581268	phosphoribosyl-AMP cyclohydrolase [Proteus hauseri].	44.94	89	49	0	24	112	16	104	7e-23	99.4
rs:WP_013509724	phosphoribosyl-AMP cyclohydrolase [Pantoea sp. At-9b].	44.79	96	53	0	23	118	16	111	7e-23	99.4
rs:WP_046356005	phosphoribosyl-ATP pyrophosphatase [Pseudoalteromonas luteoviolacea].	41.67	108	58	1	14	121	7	109	7e-23	99.4
sp:HIS2_BACTN	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	44.12	102	51	2	11	112	3	98	7e-23	99.4
rs:WP_035014967	phosphoribosyl-ATP pyrophosphatase [Catenovulum agarivorans].	46.15	91	49	0	22	112	17	107	7e-23	99.4
rs:WP_007776270	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Cronobacter].	46.07	89	48	0	24	112	17	105	7e-23	99.4
rs:WP_037081921	hypothetical protein [Pseudoxanthomonas sp. J35].	51.65	91	44	0	24	114	28	118	7e-23	99.8
rs:WP_020859103	histidine biosynthesis hisIE [SAR86 cluster bacterium SAR86B].	44.21	95	53	0	18	112	3	97	7e-23	99.0
rs:WP_020081646	phosphoribosyl-AMP cyclohydrolase [Flavobacterium sp. SCGC AAA160-P02].	43.30	97	53	1	17	111	2	98	7e-23	99.4
rs:WP_008915149	phosphoribosyl-AMP cyclohydrolase [Providencia sneebia].	46.81	94	48	1	19	112	14	105	7e-23	99.4
tr:Q3BUF1_XANC5	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	48.35	91	47	0	24	114	17	107	7e-23	99.4
rs:WP_044641974	hypothetical protein [Thermoactinomycetaceae bacterium GD1].	48.39	93	48	0	24	116	29	121	8e-23	100
rs:WP_031422408	phosphoribosyl-ATP pyrophosphatase [Xanthomonas axonopodis].	48.35	91	47	0	24	114	22	112	8e-23	99.4
rs:WP_044200844	phosphoribosyl-AMP cyclohydrolase [Flammeovirga sp. OC4].	42.02	119	56	4	7	117	8	121	8e-23	97.4
rs:WP_011347190	phosphoribosyl-AMP cyclohydrolase [Xanthomonas euvesicatoria].	48.35	91	47	0	24	114	22	112	8e-23	99.4
rs:WP_013304023	phosphoribosyl-AMP cyclohydrolase [Ignisphaera aggregans].	43.88	98	55	0	21	118	23	120	8e-23	97.4
sp:HIS2_BLOFL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	46.32	95	51	0	24	118	17	111	8e-23	99.4
rs:WP_034945871	phosphoribosyl-ATP pyrophosphatase [Gilliamella apicola].	46.07	89	48	0	24	112	22	110	8e-23	99.4
rs:WP_012782447	phosphoribosyl-AMP cyclohydrolase [Flavobacteriaceae bacterium 3519-10].	42.20	109	57	1	11	119	3	105	8e-23	99.0
tr:C2SYE2_BACCE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	55.41	74	33	0	40	113	1	74	8e-23	95.9
rs:WP_029972252	imidazole glycerol phosphate synthase, partial [Prochlorococcus sp. scB241_529D18].	56.41	78	34	0	12	89	6	83	8e-23	96.3
rs:WP_045969890	phosphoribosyl-ATP pyrophosphatase [Xenorhabdus doucetiae].	48.89	90	46	0	23	112	21	110	8e-23	99.4
rs:WP_036081097	hypothetical protein [Leptospirillum ferriphilum].	47.31	93	49	0	20	112	7	99	8e-23	99.8
rs:WP_043958240	phosphoribosyl-ATP pyrophosphatase [Lysobacter sp. A03].	51.11	90	44	0	23	112	15	104	8e-23	99.4
rs:WP_022698383	phosphoribosyl-AMP cyclohydrolase [Maricaulis sp. JL2009].	48.08	104	53	1	9	112	9	111	8e-23	99.4
rs:WP_008219458	phosphoribosyl-AMP cyclohydrolase [Rheinheimera nanhaiensis].	39.13	115	67	1	16	130	7	118	8e-23	99.4
rs:WP_012124345	phosphoribosyl-AMP cyclohydrolase [Cronobacter sakazakii].	46.07	89	48	0	24	112	17	105	8e-23	99.4
rs:WP_012619431	histidine biosynthesis bifunctional protein HisIE [Buchnera aphidicola].	46.07	89	48	0	24	112	17	105	8e-23	99.4
rs:WP_014498835	phosphoribosyl-AMP cyclohydrolase [Buchnera aphidicola].	46.07	89	48	0	24	112	17	105	8e-23	99.4
rs:WP_016928407	phosphoribosyl-AMP cyclohydrolase [Serratia marcescens].	43.16	95	54	0	24	118	17	111	8e-23	99.4
rs:WP_035624032	phosphoribosyl-ATP pyrophosphatase [Flavobacterium hydatis].	43.56	101	54	1	11	111	1	98	8e-23	99.0
rs:WP_032981028	phosphoribosyl-ATP pyrophosphatase [Cronobacter malonaticus].	46.07	89	48	0	24	112	17	105	8e-23	99.4
rs:WP_026993238	phosphoribosyl-ATP pyrophosphatase [Flavobacterium subsaxonicum].	43.69	103	57	1	18	119	3	105	9e-23	99.0
rs:WP_028380273	phosphoribosyl-ATP pyrophosphatase [Legionella cherrii].	47.19	89	47	0	24	112	16	104	9e-23	99.4
rs:WP_021971995	phosphoribosyl-ATP diphosphatase [Bacteroides sp. CAG:1076].	47.19	89	47	0	24	112	10	98	9e-23	99.4
rs:WP_014264242	phosphoribosyl-AMP cyclohydrolase [Granulicella mallensis].	44.76	105	50	2	10	112	5	103	9e-23	97.1
rs:WP_014734741	phosphoribosyl-ATP pyrophosphatase [Pyrococcus sp. ST04].	54.12	85	38	1	29	113	2	85	9e-23	99.0
sp:HIS3_CENSY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	41.35	104	60	1	11	113	1	104	9e-23	96.7
rs:WP_023524690	histidine biosynthesis bifunctional protein (HisIE) [Leptospirillum sp. Group II 'C75'].	47.31	93	49	0	20	112	21	113	9e-23	99.8
rs:WP_010846863	histidine biosynthesis protein HisIE [Xenorhabdus nematophila].	48.31	89	46	0	24	112	22	110	9e-23	99.4
tr:A0A0A8UUI2_LEGHA	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	50.00	92	46	0	24	115	15	106	9e-23	99.0
rs:WP_036682712	phosphoribosyl-AMP cyclohydrolase [Pelobacter seleniigenes].	45.54	101	47	2	21	113	8	108	9e-23	97.1
rs:WP_039527556	phosphoribosyl-ATP pyrophosphatase [Xanthomonas arboricola].	48.31	89	46	0	24	112	22	110	9e-23	99.4
rs:WP_039513761	phosphoribosyl-ATP pyrophosphatase, partial [Xanthomonas arboricola].	48.31	89	46	0	24	112	22	110	9e-23	97.4
rs:WP_018137447	phosphoribosyl-ATP pyrophosphatase [Campylobacter curvus].	43.01	93	52	1	23	114	12	104	9e-23	99.8
rs:WP_015835009	phosphoribosyl-AMP cyclohydrolase [Photorhabdus asymbiotica].	45.45	88	48	0	25	112	18	105	9e-23	99.0
tr:J9ZFP0_LEPFM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	47.31	93	49	0	20	112	21	113	9e-23	99.8
rs:WP_009113214	phosphoribosyl-AMP cyclohydrolase [Brenneria sp. EniD312].	44.21	95	53	0	24	118	17	111	9e-23	99.0
rs:WP_013766203	phosphoribosyl-AMP cyclohydrolase [Haliscomenobacter hydrossis].	40.78	103	60	1	10	111	2	104	1e-22	99.0
rs:WP_023648726	phosphoribosyl-AMP cyclohydrolase [Candidatus Pelagibacter ubique].	44.76	105	57	1	17	120	18	122	1e-22	97.8
rs:WP_042823314	phosphoribosyl-ATP pyrophosphatase [Xanthomonas axonopodis].	48.35	91	47	0	24	114	22	112	1e-22	99.0
tr:A0A059Y0Z4_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	47.31	93	49	0	20	112	15	107	1e-22	99.4
rs:WP_008614416	phosphoribosyl-AMP cyclohydrolase [Joostella marina].	41.76	91	53	0	21	111	8	98	1e-22	99.0
rs:WP_037589522	phosphoribosyl-ATP pyrophosphatase [Staphylococcus aureus].	42.86	91	52	0	24	114	11	101	1e-22	99.4
rs:WP_010864183	phosphoribosyl-AMP cyclohydrolase [Plesiomonas shigelloides].	47.78	90	47	0	23	112	16	105	1e-22	99.0
rs:WP_020722849	hypothetical protein [Acidobacteriaceae bacterium KBS 96].	47.12	104	48	2	11	113	5	102	1e-22	97.1
rs:WP_015732819	phosphoribosyl-AMP cyclohydrolase [Methanocaldococcus vulcanius].	50.00	94	46	1	25	118	22	114	1e-22	97.1
rs:WP_005818397	phosphoribosyl-AMP cyclohydrolase [Actinobacillus minor].	46.67	90	48	0	24	113	14	103	1e-22	99.4
rs:WP_036780006	phosphoribosyl-ATP pyrophosphatase [Photorhabdus luminescens].	45.56	90	49	0	23	112	16	105	1e-22	99.0
rs:WP_039435220	phosphoribosyl-ATP pyrophosphatase [Xanthomonas vasicola].	48.35	91	47	0	24	114	22	112	1e-22	99.0
rs:WP_024937741	phosphoribosyl-ATP pyrophosphatase [Xanthomonas arboricola].	48.31	89	46	0	24	112	22	110	1e-22	99.0
rs:WP_006086289	phosphoribosyl-AMP cyclohydrolase [Shewanella baltica].	48.31	89	46	0	24	112	21	109	1e-22	99.4
tr:F7Z4H7_BACC6	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	45.54	101	46	1	40	131	1	101	1e-22	99.0
rs:WP_023903819	phosphoribosyl-AMP cyclohydrolase [Xanthomonas hortorum].	48.31	89	46	0	24	112	24	112	1e-22	99.0
rs:WP_033750134	phosphoribosyl-ATP pyrophosphatase [Pantoea sp. NGS-ED-1003].	45.26	95	52	0	24	118	17	111	1e-22	99.0
rs:WP_006450775	phosphoribosyl-AMP cyclohydrolase [Xanthomonas gardneri].	48.31	89	46	0	24	112	24	112	1e-22	99.0
rs:WP_046672346	phosphoribosyl-ATP pyrophosphatase [Sphingobacterium sp. Ag1].	46.15	91	49	0	24	114	9	99	1e-22	98.6
rs:WP_039045563	phosphoribosyl-ATP pyrophosphatase [Plesiomonas shigelloides].	47.78	90	47	0	23	112	16	105	1e-22	99.0
rs:WP_028762060	phosphoribosyl-ATP pyrophosphatase [Shewanella colwelliana].	42.34	111	58	1	2	112	1	105	1e-22	99.0
rs:WP_008582703	phosphoribosyl-AMP cyclohydrolase [Niabella soli].	48.31	89	46	0	24	112	10	98	1e-22	98.6
rs:WP_031571863	phosphoribosyl-ATP pyrophosphatase [Rheinheimera texasensis].	44.79	96	53	0	18	113	4	99	1e-22	99.0
rs:WP_014612894	phosphoribosyl-AMP cyclohydrolase [Staphylococcus pseudintermedius].	46.15	91	49	0	24	114	10	100	1e-22	99.0
rs:WP_039521353	phosphoribosyl-ATP pyrophosphatase [Xanthomonas arboricola].	48.31	89	46	0	24	112	22	110	1e-22	99.0
rs:WP_047256835	phosphoribosyl-ATP pyrophosphatase [Moellerella wisconsensis].	47.19	89	47	0	24	112	17	105	1e-22	99.0
rs:WP_026225081	phosphoribosyl-AMP cyclohydrolase [Candidatus Pelagibacter ubique].	44.76	105	57	1	17	120	18	122	1e-22	97.8
rs:WP_022809676	phosphoribosyl-ATP diphosphatase [Aminicenantes bacterium SCGC AAA252-K06].	42.98	114	57	3	16	129	230	335	1e-22	101
tr:A0A0D8FRN6_9ACTN	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:KJE75943.1}; EC=3.5.4.19 {ECO:0000313|EMBL:KJE75943.1};	45.28	106	53	3	11	112	1	105	1e-22	96.7
rs:WP_021088160	phosphoribosyl-AMP cyclohydrolase [Campylobacter concisus].	48.91	92	46	1	24	114	15	106	1e-22	99.8
tr:J9FRB5_9ZZZZ	SubName: Full=Phosphoribosyl-ATP diphosphatase {ECO:0000313|EMBL:EJW97023.1};	41.18	102	54	1	11	112	3	98	1e-22	98.6
rs:WP_022623382	phosphoribosyl-AMP cyclohydrolase [Pantoea ananatis].	44.21	95	53	0	24	118	17	111	1e-22	99.0
rs:WP_027073999	phosphoribosyl-ATP pyrophosphatase [Mannheimia granulomatis].	46.67	90	48	0	24	113	15	104	1e-22	99.0
rs:WP_013702596	phosphoribosyl-ATP diphosphatase [Treponema succinifaciens].	49.44	89	44	1	24	112	251	338	1e-22	101
rs:WP_041185798	phosphoribosyl-AMP cyclohydrolase [Candidatus Pelagibacter ubique].	44.76	105	57	1	17	120	18	122	1e-22	97.8
rs:WP_046554150	phosphoribosyl-ATP pyrophosphatase [Arsukibacterium sp. MJ3].	41.67	108	60	1	23	130	18	122	1e-22	99.0
rs:WP_037542201	phosphoribosyl-ATP pyrophosphatase [Staphylococcus pseudintermedius].	46.15	91	49	0	24	114	10	100	1e-22	99.0
tr:K0XIM9_9PORP	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	42.98	114	64	1	11	123	1	114	1e-22	98.6
rs:WP_010229463	phosphoribosyl-AMP cyclohydrolase [Gillisia marina].	43.96	91	51	0	21	111	8	98	1e-22	99.0
rs:WP_045283840	phosphoribosyl-ATP pyrophosphatase [Shewanella algae].	45.05	91	50	0	22	112	19	109	1e-22	99.0
tr:Q6IU38_ECOLX	SubName: Full=HisI {ECO:0000313|EMBL:AAT42465.1}; Flags: Fragment;	48.81	84	43	0	29	112	2	85	1e-22	97.8
rs:WP_039198896	phosphoribosyl-ATP pyrophosphatase [Actinobacillus equuli].	45.56	90	49	0	24	113	12	101	1e-22	99.0
rs:WP_044734599	phosphoribosyl-ATP pyrophosphatase [Shewanella algae].	45.05	91	50	0	22	112	19	109	1e-22	99.0
rs:WP_025887726	phosphoribosyl-ATP pyrophosphatase [Shewanella haliotis].	45.05	91	50	0	22	112	19	109	1e-22	99.0
rs:WP_029416037	imidazole glycerol phosphate synthase [Brevundimonas bacteroides].	44.64	112	61	1	13	123	2	113	1e-22	99.0
rs:WP_047125464	phosphoribosyl-ATP pyrophosphatase [Xanthomonas arboricola].	48.31	89	46	0	24	112	22	110	1e-22	99.0
tr:Q4FL88_PELUB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	45.63	103	55	1	19	120	27	129	1e-22	97.8
rs:WP_037038944	phosphoribosyl-ATP pyrophosphatase [Rahnella aquatilis].	44.33	97	54	0	24	120	17	113	1e-22	98.6
rs:WP_032098886	phosphoribosyl-ATP pyrophosphatase [Morganella morganii].	48.31	89	46	0	24	112	17	105	1e-22	98.6
rs:WP_005967573	phosphoribosyl-AMP cyclohydrolase [Pectobacterium wasabiae].	42.11	95	55	0	24	118	23	117	1e-22	99.0
rs:WP_020851328	histidine biosynthesis bifunctional protein HisIE [Xylella fastidiosa].	50.56	89	44	0	24	112	22	110	1e-22	98.6
sp:HIS2_PHOLL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01019}; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_01019}; Short=PRA-PH {ECO:0000255|HAMAP-Rule:MF_01019}; EC=3.6.1.31 {ECO:0000255|HAMAP-Rule:MF_01019};	45.56	90	49	0	23	112	16	105	1e-22	98.6
rs:WP_034744480	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium vrystaatense].	44.79	96	52	1	18	112	3	98	1e-22	98.6
rs:WP_046342441	phosphoribosyl-ATP pyrophosphatase [Xanthomonas campestris].	48.31	89	46	0	24	112	22	110	1e-22	98.6
rs:WP_019539136	hypothetical protein [Proteiniphilum acetatigenes].	43.14	102	52	1	11	112	3	98	1e-22	98.6
rs:WP_013026354	phosphoribosyl-AMP cyclohydrolase [Pantoea ananatis].	44.21	95	53	0	24	118	17	111	1e-22	98.6
tr:F3PAX5_9ACTO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	53.09	81	38	0	40	120	1	81	1e-22	95.5
rs:WP_020211742	hypothetical protein [Flavobacterium rivuli].	47.42	97	44	3	20	112	5	98	1e-22	98.6
rs:WP_032111923	phosphoribosyl-AMP cyclohydrolase [bacterium OL-1].	47.73	88	46	0	26	113	1	88	2e-22	95.9
tr:H2IUR1_RAHAC	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	44.33	97	54	0	24	120	26	122	2e-22	99.0
rs:WP_012142888	phosphoribosyl-AMP cyclohydrolase [Shewanella sediminis].	47.25	91	48	0	22	112	17	107	2e-22	98.6
rs:WP_043899018	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Pectobacterium].	42.55	94	54	0	25	118	1	94	2e-22	98.2
rs:WP_022828142	phosphoribosyl-AMP cyclohydrolase [Flavobacterium antarcticum].	47.25	91	48	0	24	114	10	100	2e-22	98.2
rs:WP_015729687	phosphoribosyl-AMP cyclohydrolase [Staphylococcus pseudintermedius].	46.15	91	49	0	24	114	10	100	2e-22	98.6
rs:WP_036971977	phosphoribosyl-ATP pyrophosphatase [Pseudoalteromonas lipolytica].	46.24	93	50	0	20	112	13	105	2e-22	98.6
rs:WP_006119834	phosphoribosyl-AMP cyclohydrolase [Pantoea stewartii].	44.21	95	53	0	24	118	17	111	2e-22	98.6
rs:WP_028724853	phosphoribosyl-ATP pyrophosphatase [Pantoea ananatis].	44.21	95	53	0	24	118	17	111	2e-22	98.6
rs:WP_029568972	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Pantoea].	44.21	95	53	0	24	118	17	111	2e-22	98.6
sp:HIS2_BUCAI	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	46.07	89	48	0	24	112	17	105	2e-22	98.6
rs:WP_007616929	histidine biosynthesis bifunctional protein hisIE [Glaciecola arctica].	49.44	89	45	0	24	112	18	106	2e-22	98.6
rs:WP_028781461	phosphoribosyl-ATP pyrophosphatase [Shewanella sp. 38A_GOM-205m].	45.05	91	50	0	22	112	19	109	2e-22	98.6
rs:WP_043993207	phosphoribosyl-ATP pyrophosphatase [Actinobacillus pleuropneumoniae].	46.07	89	48	0	25	113	12	100	2e-22	98.6
rs:WP_007888883	phosphoribosyl-AMP cyclohydrolase [Pantoea sp. GM01].	43.75	96	54	0	23	118	16	111	2e-22	98.6
rs:WP_045089389	phosphoribosyl-ATP pyrophosphatase [Porphyromonadaceae bacterium ING2-E5B].	42.16	102	53	1	11	112	3	98	2e-22	98.2
tr:D9P2X8_ACTPL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	46.07	89	48	0	25	113	14	102	2e-22	98.6
rs:WP_027307052	phosphoribosyl-AMP cyclohydrolase [Candidatus Pelagibacter ubique].	44.76	105	57	1	17	120	18	122	2e-22	97.4
rs:WP_005702100	phosphoribosyl-AMP cyclohydrolase [Aggregatibacter aphrophilus].	45.65	92	50	0	24	115	11	102	2e-22	98.2
rs:WP_007699398	phosphoribosyl-AMP cyclohydrolase [Cronobacter universalis].	46.07	89	48	0	24	112	17	105	2e-22	98.6
rs:WP_005704737	phosphoribosyl-AMP cyclohydrolase [Aggregatibacter aphrophilus].	45.65	92	50	0	24	115	11	102	2e-22	98.2
rs:WP_010663279	phosphoribosyl-AMP cyclohydrolase [Marinilabilia salmonicolor].	44.94	89	49	0	24	112	11	99	2e-22	98.2
rs:WP_004571309	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pantoea].	44.21	95	53	0	24	118	17	111	2e-22	98.6
rs:WP_043881916	phosphoribosyl-ATP pyrophosphatase [Pectobacterium carotovorum].	42.55	94	54	0	25	118	1	94	2e-22	98.2
rs:WP_025976212	imidazole glycerol phosphate synthase [Brevundimonas naejangsanensis].	44.74	114	62	1	11	123	1	114	2e-22	98.6
rs:WP_009874061	phosphoribosyl-AMP cyclohydrolase [Buchnera aphidicola].	46.07	89	48	0	24	112	17	105	2e-22	98.6
rs:WP_034732739	phosphoribosyl-ATP pyrophosphatase [Idiomarina sp. MCCC 1A10513].	47.78	90	47	0	25	114	12	101	2e-22	98.2
rs:WP_026362735	phosphoribosyl-AMP cyclohydrolase [Candidatus Pelagibacter ubique].	43.81	105	58	1	17	120	18	122	2e-22	97.1
rs:WP_006996649	phosphoribosyl-AMP cyclohydrolase [Candidatus Pelagibacter ubique].	44.76	105	57	1	17	120	18	122	2e-22	97.1
rs:WP_044017691	phosphoribosyl-ATP pyrophosphatase [Hymenobacter sp. APR13].	50.56	89	44	0	24	112	9	97	2e-22	98.6
rs:WP_039327843	phosphoribosyl-ATP pyrophosphatase [Pantoea rodasii].	43.88	98	55	0	23	120	16	113	2e-22	98.2
rs:WP_035390259	phosphoribosyl-AMP cyclohydrolase [Ferrimicrobium acidiphilum].	47.42	97	49	2	17	112	3	98	2e-22	95.9
rs:WP_028373147	phosphoribosyl-ATP pyrophosphatase [Legionella lansingensis].	49.44	89	45	0	24	112	16	104	2e-22	98.2
tr:A0A094J7L7_9GAMM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	47.78	90	47	0	25	114	19	108	2e-22	98.2
rs:WP_034258353	phosphoribosyl-ATP pyrophosphatase [Altibacter lentus].	48.86	88	45	0	24	111	11	98	2e-22	98.2
rs:WP_034824749	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Enterobacteriaceae].	43.88	98	55	0	23	120	16	113	2e-22	98.2
rs:WP_007065273	phosphoribosyl-AMP cyclohydrolase [Fulvimarina pelagi].	46.39	97	50	1	19	113	23	119	2e-22	96.7
rs:WP_029219681	phosphoribosyl-ATP pyrophosphatase [Xanthomonas cassavae].	47.83	92	48	0	23	114	21	112	2e-22	98.2
rs:WP_032972224	phosphoribosyl-ATP pyrophosphatase [Cronobacter malonaticus].	46.07	89	48	0	24	112	17	105	2e-22	98.2
rs:WP_037034541	imidazole glycerol phosphate synthase [Pseudoxanthomonas sp. J31].	46.60	103	49	1	10	112	7	103	2e-22	98.6
tr:K2A8G6_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	38.60	114	56	1	23	122	2	115	2e-22	97.8
rs:WP_019232040	phosphoribosyl-AMP cyclohydrolase [Legionella anisa].	47.19	89	47	0	24	112	16	104	2e-22	98.2
rs:WP_034548517	phosphoribosyl-ATP diphosphatase [Helicobacter cinaedi].	44.57	92	51	0	25	116	15	106	2e-22	99.0
rs:WP_025905113	phosphoribosyl-ATP pyrophosphatase [Staphylococcus sciuri].	42.86	91	52	0	24	114	11	101	2e-22	98.2
rs:WP_011278397	phosphoribosyl-AMP cyclohydrolase [Sulfolobus acidocaldarius].	47.73	88	46	0	26	113	29	116	2e-22	96.3
tr:C3AJF6_BACMY	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	48.86	88	45	0	26	113	1	88	2e-22	95.1
rs:WP_015671669	phosphoribosyl-AMP cyclohydrolase [Serratia marcescens].	42.11	95	55	0	24	118	17	111	2e-22	98.2
rs:WP_008911965	phosphoribosyl-AMP cyclohydrolase [Providencia burhodogranariea].	46.59	88	47	0	25	112	18	105	2e-22	98.2
rs:WP_012349527	phosphoribosyl-AMP cyclohydrolase [Pyrobaculum neutrophilum].	48.89	90	46	0	23	112	40	129	2e-22	96.7
rs:WP_015453590	histidine biosynthesis [Helicobacter cinaedi].	44.57	92	51	0	25	116	15	106	2e-22	99.0
rs:WP_004083403	phosphoribosyl-AMP cyclohydrolase [Xylella fastidiosa].	50.56	89	44	0	24	112	22	110	2e-22	98.2
rs:WP_021509350	phosphoribosyl-AMP cyclohydrolase [Pantoea dispersa].	44.79	96	53	0	23	118	16	111	2e-22	98.2
rs:WP_026861939	phosphoribosyl-ATP pyrophosphatase [Idiomarina sediminum].	50.00	88	44	0	25	112	19	106	2e-22	98.2
rs:WP_042612616	phosphoribosyl-ATP pyrophosphatase [Stenotrophomonas maltophilia].	44.21	95	53	0	24	118	22	116	2e-22	98.2
tr:A7ZFL7_CAMC1	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	48.91	92	46	1	24	114	15	106	2e-22	99.0
rs:WP_015385638	phosphoribosyl-AMP cyclohydrolase [Sulfolobus acidocaldarius].	47.73	88	46	0	26	113	24	111	2e-22	95.9
rs:WP_008104832	phosphoribosyl-AMP cyclohydrolase [Pantoea sp. YR343].	43.75	96	54	0	23	118	16	111	2e-22	98.2
rs:WP_044165131	phosphoribosyl-ATP pyrophosphatase [Bacteroides reticulotermitis].	43.75	96	53	1	18	112	3	98	2e-22	97.8
rs:WP_035315273	phosphoribosyl-AMP cyclohydrolase [Brochothrix campestris].	46.08	102	53	2	17	116	2	103	2e-22	95.9
rs:WP_014964334	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Nitrosopumilus].	38.46	104	58	1	11	114	8	105	2e-22	95.5
rs:WP_028767134	phosphoribosyl-ATP pyrophosphatase [Shewanella fidelis].	47.78	90	47	0	23	112	24	113	3e-22	98.2
rs:WP_021071378	phosphoribosyl-AMP cyclohydrolase [Sphingobacterium paucimobilis].	46.15	91	49	0	24	114	9	99	3e-22	97.8
rs:WP_040975446	phosphoribosyl-ATP pyrophosphatase [Pasteurella sp. FF6].	44.79	96	53	0	23	118	14	109	3e-22	98.2
rs:WP_046893799	phosphoribosyl-ATP pyrophosphatase [Morganella morganii].	47.19	89	47	0	24	112	17	105	3e-22	97.8
rs:WP_021033118	phosphoribosyl-AMP cyclohydrolase, partial [Pseudoalteromonas undina].	43.01	93	53	0	20	112	13	105	3e-22	97.4
rs:WP_022437733	phosphoribosyl-ATP diphosphatase [Prevotella sp. CAG:279].	47.78	90	47	0	23	112	9	98	3e-22	97.8
rs:WP_026859148	phosphoribosyl-ATP pyrophosphatase [Jeotgalicoccus psychrophilus].	47.19	89	47	0	24	112	10	98	3e-22	98.2
rs:WP_039815695	phosphoribosyl-ATP pyrophosphatase [Xanthomonas arboricola].	48.31	89	46	0	24	112	22	110	3e-22	97.8
tr:U2HJC9_LACPN	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:ERJ61861.1}; Flags: Fragment;	51.85	81	39	0	24	104	10	90	3e-22	95.1
rs:WP_023572504	phosphoribosyl-AMP cyclohydrolase [Flavobacterium enshiense].	47.25	91	48	0	21	111	8	98	3e-22	97.8
rs:WP_022245814	phosphoribosyl-ATP diphosphatase [Clostridium sp. CAG:306].	46.08	102	49	1	11	112	222	317	3e-22	100
rs:WP_014216680	phosphoribosyl-AMP cyclohydrolase [Niastella koreensis].	48.86	88	45	0	24	111	11	98	3e-22	97.8
rs:WP_027003294	phosphoribosyl-ATP pyrophosphatase [Flexibacter roseolus].	44.44	90	50	0	23	112	9	98	3e-22	97.8
tr:B8LAG5_9GAMM	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	45.26	95	52	0	24	118	11	105	3e-22	97.8
rs:WP_026815925	phosphoribosyl-ATP pyrophosphatase [Arenimonas composti].	43.75	112	62	1	2	112	1	112	3e-22	97.8
rs:WP_002838375	phosphoribosyl-AMP cyclohydrolase [Campylobacter coli].	41.67	96	56	0	24	119	18	113	3e-22	97.8
rs:WP_016147090	hypothetical protein [Butyricicoccus pullicaecorum].	42.72	103	59	0	20	122	7	109	3e-22	95.5
rs:WP_002821060	phosphoribosyl-AMP cyclohydrolase [Campylobacter coli].	41.67	96	56	0	24	119	18	113	3e-22	97.8
rs:WP_011991773	phosphoribosyl-ATP pyrophosphatase [Campylobacter curvus].	43.01	93	52	1	23	114	12	104	3e-22	98.6
tr:H8GZS8_DEIGI	RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000256|HAMAP-Rule:MF_01020}; Short=PRA-PH {ECO:0000256|HAMAP-Rule:MF_01020}; EC=3.6.1.31 {ECO:0000256|HAMAP-Rule:MF_01020};	52.94	85	40	0	29	113	1	85	3e-22	97.8
tr:E8LMS5_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	43.93	107	57	3	24	128	27	132	3e-22	96.3
rs:WP_015853930	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Dickeya].	45.56	90	49	0	24	113	17	106	3e-22	97.8
rs:WP_027585455	phosphoribosyl-ATP pyrophosphatase [Prolixibacter bellariivorans].	44.79	96	51	1	18	111	3	98	3e-22	97.8
rs:WP_043104754	phosphoribosyl-ATP pyrophosphatase [Xanthomonas arboricola].	48.31	89	46	0	24	112	22	110	3e-22	97.8
tr:I0KFQ3_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	43.88	98	53	1	17	112	11	108	3e-22	97.8
rs:WP_018693324	hypothetical protein [Algicola sagamiensis].	47.73	88	46	0	24	111	18	105	3e-22	97.8
rs:WP_041258391	phosphoribosyl-ATP pyrophosphatase [Fibrella aestuarina].	43.88	98	53	1	17	112	2	99	3e-22	97.8
rs:WP_040007863	phosphoribosyl-ATP pyrophosphatase [Stenotrophomonas sp. SKA14].	45.26	95	52	0	24	118	22	116	3e-22	97.8
rs:WP_038274996	phosphoribosyl-AMP cyclohydrolase [actinobacterium acAMD-5].	43.16	95	54	0	18	112	7	101	3e-22	95.1
rs:WP_036169712	phosphoribosyl-ATP pyrophosphatase [Lysobacter dokdonensis].	51.96	102	43	1	11	112	3	98	3e-22	97.4
rs:WP_014646954	phosphoribosyl-AMP cyclohydrolase [Stenotrophomonas maltophilia].	45.26	95	52	0	24	118	22	116	3e-22	97.8
rs:WP_037469104	phosphoribosyl-ATP pyrophosphatase [Shewanella marina].	39.81	103	61	1	11	112	1	103	3e-22	97.8
rs:WP_017346592	phosphoribosyl-AMP cyclohydrolase [Pantoea sp. A4].	42.71	96	55	0	23	118	16	111	3e-22	97.8
rs:WP_040151033	phosphoribosyl-ATP pyrophosphatase [Photorhabdus luminescens].	45.56	90	49	0	23	112	16	105	3e-22	97.8
rs:WP_027669606	phosphoribosyl-ATP pyrophosphatase [Rheinheimera baltica].	39.67	121	69	2	11	130	1	118	3e-22	97.8
rs:WP_046305136	phosphoribosyl-ATP pyrophosphatase [Blochmannia endosymbiont of Camponotus (Colobopsis) obliquus].	44.09	93	52	0	21	113	12	104	3e-22	97.8
rs:WP_036814684	phosphoribosyl-ATP pyrophosphatase [Photorhabdus luminescens].	45.56	90	49	0	23	112	16	105	3e-22	97.8
rs:XP_001417445	predicted protein [Ostreococcus lucimarinus CCE9901].	44.34	106	57	1	17	120	49	154	3e-22	99.0
rs:WP_041812714	phosphoribosyl-AMP cyclohydrolase [Lactobacillus fermentum].	53.19	94	44	0	24	117	8	101	3e-22	95.1
rs:WP_040909511	phosphoribosyl-AMP cyclohydrolase [Succinatimonas hippei].	43.93	107	57	3	24	128	21	126	3e-22	95.9
rs:WP_033916891	phosphoribosyl-ATP diphosphatase [Campylobacter sputorum].	46.88	96	49	2	23	117	12	106	3e-22	98.6
rs:WP_008812934	phosphoribosyl-AMP cyclohydrolase [Enterobacteriaceae bacterium 9_2_54FAA].	44.33	97	54	0	24	120	22	118	4e-22	97.8
tr:A0A094RWU1_9ACTN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	43.16	95	54	0	18	112	13	107	4e-22	95.1
rs:WP_039189072	phosphoribosyl-ATP pyrophosphatase [Hafnia paralvei].	44.33	97	54	0	24	120	22	118	4e-22	97.8
rs:WP_021091053	phosphoribosyl-AMP cyclohydrolase [Campylobacter concisus].	47.83	92	47	1	24	114	15	106	4e-22	98.2
rs:WP_008486029	phosphoribosyl-AMP cyclohydrolase [Gallaecimonas xiamenensis].	42.00	100	57	1	14	112	7	106	4e-22	97.4
rs:WP_003167809	phosphoribosyl-ATP diphosphatase [Brevundimonas diminuta].	44.64	112	61	1	13	123	7	118	4e-22	97.8
rs:WP_031565323	phosphoribosyl-ATP pyrophosphatase [Legionella wadsworthii].	46.07	89	48	0	24	112	16	104	4e-22	97.8
rs:WP_038887219	phosphoribosyl-ATP pyrophosphatase [Cronobacter dublinensis].	44.94	89	49	0	24	112	17	105	4e-22	97.4
rs:WP_006869547	phosphoribosyl-AMP cyclohydrolase [Legionella drancourtii].	45.28	106	52	2	7	112	5	104	4e-22	97.4
rs:WP_043896551	phosphoribosyl-ATP pyrophosphatase, partial [Haemophilus parasuis].	46.07	89	48	0	25	113	13	101	4e-22	95.9
rs:WP_004317856	phosphoribosyl-ATP pyrophosphatase [Campylobacter concisus].	47.83	92	47	1	24	114	15	106	4e-22	98.2
rs:WP_041764758	imidazole glycerol phosphate synthase [Pseudoxanthomonas suwonensis].	46.08	102	49	1	11	112	8	103	4e-22	97.8
rs:WP_037034927	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Rahnella].	44.33	97	54	0	24	120	17	113	4e-22	97.4
rs:WP_043885407	phosphoribosyl-ATP pyrophosphatase [Pectobacterium wasabiae].	41.49	94	55	0	25	118	1	94	4e-22	97.1
tr:W4UZS6_9BACE	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	44.94	89	49	0	24	112	3	91	4e-22	97.1
tr:M5CYM0_STEMA	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	45.26	95	52	0	24	118	22	116	4e-22	97.4
rs:WP_046395511	phosphoribosyl-ATP pyrophosphatase [Photorhabdus luminescens].	44.44	90	50	0	23	112	16	105	4e-22	97.4
rs:WP_039648931	phosphoribosyl-ATP pyrophosphatase [Campylobacter insulaenigrae].	41.30	92	54	0	24	115	19	110	4e-22	97.4
rs:WP_024474087	phosphoribosyl-ATP pyrophosphatase [Morganella morganii].	47.19	89	47	0	24	112	17	105	4e-22	97.4
rs:WP_040296126	phosphoribosyl-ATP pyrophosphatase [Barnesiella intestinihominis].	44.55	101	56	0	23	123	9	109	4e-22	97.1
rs:WP_032991017	phosphoribosyl-ATP pyrophosphatase [Cronobacter dublinensis].	44.94	89	49	0	24	112	17	105	4e-22	97.4
rs:WP_039033228	phosphoribosyl-ATP pyrophosphatase [Shewanella sp. ECSMB14102].	45.05	91	50	0	22	112	19	109	5e-22	97.4
tr:K8A7A0_9ENTR	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	46.07	89	48	0	24	112	17	105	5e-22	97.4
rs:WP_007637996	histidine biosynthesis bifunctional protein hisIE [Glaciecola psychrophila].	49.44	89	45	0	24	112	18	106	5e-22	97.4
rs:WP_016524505	phosphoribosyl-ATP diphosphatase [Treponema maltophilum].	48.48	99	48	2	23	121	263	358	5e-22	99.8
rs:WP_046962529	phosphoribosyl-ATP pyrophosphatase [Xanthomonas pisi].	48.35	91	47	0	24	114	22	112	5e-22	97.4
rs:WP_021088978	phosphoribosyl-AMP cyclohydrolase [Campylobacter concisus].	47.83	92	47	1	24	114	15	106	5e-22	98.2
rs:WP_039385319	phosphoribosyl-ATP pyrophosphatase [Pantoea sp. PSNIH1].	45.56	90	49	0	23	112	16	105	5e-22	97.4
rs:WP_015791932	phosphoribosyl-AMP cyclohydrolase [Methanocaldococcus fervens].	47.00	100	52	1	25	124	25	123	5e-22	95.5
tr:H8NRS3_RAHAQ	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	44.33	97	54	0	24	120	26	122	5e-22	97.4
rs:WP_009836659	phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas tunicata].	40.71	113	64	1	11	120	1	113	5e-22	97.1
rs:WP_006956508	phosphoribosyl-AMP cyclohydrolase [Idiomarina baltica].	48.94	94	46	1	19	112	15	106	5e-22	97.1
tr:A0A099PXV9_9XANT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	48.31	89	46	0	24	112	22	110	5e-22	97.4
rs:WP_008193375	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Thermotoga].	48.39	93	46	1	25	115	3	95	5e-22	97.1
rs:WP_021085631	phosphoribosyl-AMP cyclohydrolase [Campylobacter concisus].	46.81	94	49	1	24	116	15	108	5e-22	97.8
rs:WP_007794795	phosphoribosyl-AMP cyclohydrolase [Cronobacter malonaticus].	46.07	89	48	0	24	112	17	105	5e-22	97.1
tr:M0ZZU4_SOLTU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:PGSC0003DMT400011610};	37.19	121	72	1	2	118	38	158	5e-22	96.3
rs:WP_028774121	phosphoribosyl-ATP pyrophosphatase [Shewanella waksmanii].	46.15	91	49	0	22	112	15	105	5e-22	97.1
tr:A0A0D2N3Z5_9CHLO	SubName: Full=Strain SAG 48.87 unplaced genomic scaffold scaffold00082, whole genome shotgun sequence {ECO:0000313|EMBL:KIZ07052.1}; EC=3.5.4.19 {ECO:0000313|EMBL:KIZ07052.1};	38.14	118	73	0	2	119	20	137	5e-22	98.2
rs:WP_034326689	MULTISPECIES: phosphoribosyl-ATP diphosphatase [Helicobacter].	44.09	93	52	0	25	117	15	107	5e-22	97.4
gp:AP012032_1772	histidine biosynthesis bifunctional protein HisI [Pantoea ananatis AJ13355]	43.62	94	53	0	25	118	1	94	5e-22	96.7
tr:E6WU06_PSEUU	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	46.08	102	49	1	11	112	20	115	6e-22	97.4
rs:WP_007421161	phosphoribosyl-AMP cyclohydrolase [Idiomarina sp. A28L].	45.05	91	50	0	24	114	18	108	6e-22	97.1
rs:WP_009295393	phosphoribosyl-ATP pyrophosphatase [Campylobacter sp. 10_1_50].	46.74	92	48	1	24	114	15	106	6e-22	97.8
rs:WP_021698153	phosphoribosyl-AMP cyclohydrolase [Brevundimonas abyssalis].	47.06	102	48	1	11	112	6	101	6e-22	97.1
rs:WP_044280883	phosphoribosyl-AMP cyclohydrolase [Myxococcus stipitatus].	46.36	110	57	2	11	119	1	109	6e-22	97.1
rs:WP_011330106	phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas haloplanktis].	43.01	93	53	0	20	112	13	105	6e-22	97.1
rs:WP_044223742	phosphoribosyl-AMP cyclohydrolase [Flammeovirga pacifica].	43.69	103	51	2	23	118	20	122	6e-22	95.1
tr:A0A060HLE3_9ARCH	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:AIC16318.1}; EC=3.5.4.19 {ECO:0000313|EMBL:AIC16318.1};	42.11	95	55	0	23	117	15	109	6e-22	94.7
rs:WP_041689068	phosphoribosyl-ATP pyrophosphatase [Rahnella sp. Y9602].	44.33	97	54	0	24	120	17	113	6e-22	97.1
rs:WP_037291431	phosphoribosyl-ATP pyrophosphatase [Rikenella microfusus].	42.57	101	58	0	12	112	4	104	6e-22	97.1
rs:WP_021111150	phosphoribosyl-ATP diphosphatase [Haemophilus parasuis].	46.07	89	48	0	25	113	13	101	7e-22	97.1
tr:H0UEQ5_BRELA	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	53.57	84	39	0	29	112	2	85	7e-22	96.7
rs:WP_034892999	phosphoribosyl-ATP pyrophosphatase [Gillisia sp. Hel_I_29].	46.15	91	49	0	21	111	8	98	7e-22	97.1
rs:WP_016911681	hypothetical protein [Staphylococcus vitulinus].	42.86	91	52	0	24	114	11	101	7e-22	97.1
rs:WP_038883265	phosphoribosyl-ATP pyrophosphatase [Cronobacter dublinensis].	46.07	89	48	0	24	112	17	105	7e-22	96.7
rs:WP_005997419	phosphoribosyl-AMP cyclohydrolase [Xanthomonas vesicatoria].	47.25	91	48	0	24	114	22	112	7e-22	97.1
rs:WP_026706377	phosphoribosyl-ATP pyrophosphatase [Flavobacterium soli].	48.31	89	46	0	24	112	10	98	7e-22	96.7
rs:WP_028889728	phosphoribosyl-ATP pyrophosphatase [Tenacibaculum ovolyticum].	44.94	89	49	0	24	112	10	98	7e-22	96.7
rs:WP_015878823	phosphoribosyl-AMP cyclohydrolase [Tolumonas auensis].	49.44	89	45	0	24	112	19	107	7e-22	97.1
rs:WP_014158642	phosphoribosyl-AMP cyclohydrolase [Blattabacterium sp. (Mastotermes darwiniensis)].	42.22	90	52	0	22	111	13	102	7e-22	96.7
tr:E6PHS2_9ZZZZ	SubName: Full=Phosphoribosyl-AMP cyclohydrolase phosphoribosyl-ATP pyrophosphohydrolase {ECO:0000313|EMBL:CBH76010.1}; EC=3.5.4.19 {ECO:0000313|EMBL:CBH76010.1}; EC=3.6.1.31 {ECO:0000313|EMBL:CBH76010.1};	46.94	98	52	0	15	112	3	100	7e-22	97.1
rs:WP_014667536	phosphoribosyl-ATP pyrophosphatase [Helicobacter cinaedi].	43.48	92	52	0	25	116	15	106	7e-22	97.8
tr:A0A069CZV7_9BACE	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	43.75	96	53	1	17	111	4	99	7e-22	97.1
rs:XP_002970362	hypothetical protein SELMODRAFT_411322 [Selaginella moellendorffii].	42.57	101	58	0	18	118	63	163	7e-22	98.2
rs:WP_024996124	phosphoribosyl-ATP pyrophosphatase [Bacteroides graminisolvens].	43.75	96	53	1	17	111	2	97	7e-22	96.7
tr:K8B330_9ENTR	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	46.07	89	48	0	24	112	17	105	7e-22	96.7
rs:XP_002968126	hypothetical protein SELMODRAFT_409257 [Selaginella moellendorffii].	42.57	101	58	0	18	118	63	163	7e-22	98.2
tr:S3FFI5_9BACL	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	52.70	74	35	0	44	117	1	74	7e-22	93.6
rs:WP_034585554	phosphoribosyl-ATP diphosphatase [Helicobacter magdeburgensis].	42.99	107	54	1	25	131	15	114	7e-22	97.4
rs:WP_017800218	phosphoribosyl-AMP cyclohydrolase [Erwinia toletana].	43.16	95	54	0	24	118	17	111	7e-22	96.7
gp:CP002505_1745	phosphoribosyl-ATP diphosphatase [Rahnella sp. Y9602]	44.33	97	54	0	24	120	26	122	7e-22	97.1
rs:WP_044002120	phosphoribosyl-ATP pyrophosphatase [Hymenobacter swuensis].	49.44	89	45	0	24	112	21	109	7e-22	97.1
rs:WP_022939795	phosphoribosyl-AMP cyclohydrolase [Psychromonas hadalis].	43.82	89	50	0	24	112	19	107	7e-22	96.7
tr:M0ZZU8_SOLTU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:PGSC0003DMT400011614};	37.19	121	72	1	2	118	38	158	8e-22	96.3
rs:WP_015461868	phosphoribosyl-AMP cyclohydrolase [Edwardsiella piscicida].	46.07	89	48	0	24	112	22	110	8e-22	97.1
rs:WP_013759471	phosphoribosyl-ATP diphosphatase [Treponema brennaborense].	43.56	101	56	1	12	112	239	338	8e-22	99.0
rs:WP_024740814	phosphoribosyl-ATP pyrophosphatase [Tenacibaculum maritimum].	39.29	112	58	1	21	122	8	119	8e-22	96.7
rs:WP_021084129	phosphoribosyl-AMP cyclohydrolase [Campylobacter concisus].	47.83	92	47	1	24	114	15	106	8e-22	97.4
rs:WP_025153608	phosphoribosyl-ATP pyrophosphatase [Morganella morganii].	47.19	89	47	0	24	112	17	105	8e-22	96.7
rs:WP_045137994	phosphoribosyl-ATP pyrophosphatase [Morganella morganii].	47.19	89	47	0	24	112	17	105	8e-22	96.7
tr:A0A0C5VWX5_9ENTR	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	44.33	97	54	0	24	120	22	118	8e-22	96.7
rs:WP_013268453	phosphoribosyl-AMP cyclohydrolase [Brevundimonas subvibrioides].	42.98	114	64	1	11	123	1	114	8e-22	96.7
rs:WP_031580102	phosphoribosyl-ATP pyrophosphatase [Ruminobacter sp. RM87].	43.27	104	51	1	17	112	5	108	8e-22	96.3
rs:WP_006793442	phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas sp. BSi20480].	43.01	93	53	0	20	112	13	105	8e-22	96.7
tr:C2UBB2_BACCE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	54.05	74	34	0	40	113	1	74	8e-22	93.2
rs:WP_027305108	phosphoribosyl-ATP pyrophosphatase [Campylobacter cuniculorum].	43.96	91	51	0	25	115	19	109	8e-22	96.7
tr:D4ZLB7_SHEVD	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	46.15	91	49	0	22	112	10	100	9e-22	96.7
tr:W8F588_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	49.44	89	45	0	24	112	9	97	9e-22	96.7
rs:WP_021117434	phosphoribosyl-ATP diphosphatase [Haemophilus parasuis].	46.07	89	48	0	25	113	13	101	9e-22	96.7
rs:WP_021112939	phosphoribosyl-ATP diphosphatase [Haemophilus parasuis].	46.07	89	48	0	25	113	13	101	9e-22	96.7
rs:WP_002626265	phosphoribosyl-AMP cyclohydrolase [Cystobacter fuscus].	46.60	103	53	2	11	112	1	102	9e-22	96.7
rs:WP_041419904	phosphoribosyl-ATP pyrophosphatase [Shewanella violacea].	46.15	91	49	0	22	112	20	110	9e-22	96.7
rs:WP_034855534	phosphoribosyl-ATP pyrophosphatase [Ignatzschineria larvae].	45.45	88	48	0	25	112	15	102	9e-22	96.3
tr:A0A075MRX4_9ARCH	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:AIF82159.1}; EC=3.5.4.19 {ECO:0000313|EMBL:AIF82159.1};	39.45	109	62	1	9	117	5	109	9e-22	94.4
tr:L7UF12_MYXSD	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	46.30	108	56	2	13	119	2	108	9e-22	96.7
rs:WP_039731733	imidazole glycerol phosphate synthase [Pseudoxanthomonas sp. GW2].	45.63	103	50	1	10	112	7	103	1e-21	96.7
rs:WP_025874822	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Stenotrophomonas].	44.44	99	50	1	24	122	22	115	1e-21	96.7
rs:WP_024601620	phosphoribosyl-ATP pyrophosphatase [Pseudoalteromonas atlantica].	43.01	93	53	0	20	112	13	105	1e-21	96.3
rs:WP_016706656	phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas haloplanktis].	45.16	93	51	0	20	112	13	105	1e-21	96.3
rs:WP_046561484	phosphoribosyl-ATP diphosphatase [Kangiella geojedonensis].	45.13	113	58	1	16	128	222	330	1e-21	98.6
rs:WP_008138598	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas].	43.01	93	53	0	20	112	13	105	1e-21	96.3
rs:WP_021964065	phosphoribosyl-ATP diphosphatase [Prevotella sp. CAG:1185].	44.94	89	49	0	24	112	10	98	1e-21	96.3
rs:WP_013463284	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Alteromonadales].	43.01	93	53	0	20	112	13	105	1e-21	96.3
rs:WP_028892026	phosphoribosyl-ATP pyrophosphatase [Tenacibaculum sp. 47A_GOM-205m].	42.70	89	51	0	24	112	10	98	1e-21	96.3
tr:C3GYG4_BACTU	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	54.05	74	34	0	40	113	1	74	1e-21	93.2
rs:WP_027375083	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium sp. UNC8MFCol].	40.52	116	59	2	18	123	3	118	1e-21	96.3
tr:C3FHL4_BACTB	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	54.05	74	34	0	40	113	1	74	1e-21	93.2
rs:WP_024598088	phosphoribosyl-ATP pyrophosphatase [Pseudoalteromonas haloplanktis].	43.01	93	53	0	20	112	13	105	1e-21	96.3
rs:WP_008112594	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas].	43.01	93	53	0	20	112	13	105	1e-21	96.3
rs:WP_025122748	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Serratia].	43.16	95	54	0	24	118	17	111	1e-21	96.3
rs:WP_034714742	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium soli].	41.18	102	54	1	11	112	3	98	1e-21	95.9
rs:WP_022564560	HisI protein [Candidatus Pantoea carbekii].	43.01	93	53	0	23	115	16	108	1e-21	96.3
rs:WP_038862014	phosphoribosyl-ATP pyrophosphatase [Cronobacter muytjensii].	46.07	89	48	0	24	112	17	105	1e-21	96.3
rs:WP_033783633	phosphoribosyl-ATP pyrophosphatase [Pantoea sp. 9140].	38.46	117	66	1	2	118	1	111	1e-21	96.3
rs:WP_013358441	phosphoribosyl-AMP cyclohydrolase [Pantoea vagans].	38.46	117	66	1	2	118	1	111	1e-21	96.3
rs:WP_025476243	hypothetical protein, partial [Yersinia pestis].	49.38	81	41	0	25	105	18	98	1e-21	93.6
rs:WP_022786094	phosphoribosyl-AMP cyclohydrolase [Clostridiales bacterium NK3B98].	44.12	102	56	1	13	114	2	102	1e-21	94.0
rs:WP_010457639	phosphoribosyl-AMP cyclohydrolase [Succinivibrionaceae bacterium WG-1].	44.32	88	49	0	25	112	21	108	1e-21	95.5
rs:WP_005416333	phosphoribosyl-AMP cyclohydrolase [Stenotrophomonas maltophilia].	46.07	89	48	0	24	112	22	110	1e-21	96.3
rs:WP_024353751	imidazole glycerol phosphate synthase [Brevundimonas naejangsanensis].	43.75	112	62	1	13	123	2	113	1e-21	96.3
gpu:CP011509_6217	Phosphoribosyl-AMP cyclohydrolase [Archangium gephyra]	46.53	101	52	2	13	112	2	101	1e-21	96.3
rs:WP_021805010	phosphoribosyl-AMP cyclohydrolase [Serratia fonticola].	43.16	95	54	0	24	118	17	111	1e-21	96.3
rs:WP_021179973	phosphoribosyl-AMP cyclohydrolase [Serratia fonticola].	43.16	95	54	0	24	118	17	111	1e-21	96.3
rs:WP_038053634	phosphoribosyl-ATP pyrophosphatase [Thermotoga sp. Mc24].	47.31	93	47	1	25	115	3	95	1e-21	95.9
rs:WP_026474739	phosphoribosyl-ATP pyrophosphatase [Alkaliflexus imshenetskii].	46.59	88	47	0	24	111	11	98	1e-21	95.9
rs:WP_024031734	phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas sp. NW 4327].	43.01	93	53	0	20	112	13	105	1e-21	96.3
rs:WP_010556207	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas].	43.01	93	53	0	20	112	13	105	1e-21	96.3
rs:WP_003166151	phosphoribosyl-AMP cyclohydrolase [Brevundimonas diminuta].	42.02	119	63	1	11	123	1	119	1e-21	96.3
rs:WP_034737747	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium indologenes].	40.52	116	59	2	18	123	3	118	1e-21	95.9
rs:WP_039625108	phosphoribosyl-ATP pyrophosphatase [Campylobacter lari].	40.45	89	53	0	24	112	19	107	1e-21	96.3
rs:WP_024911813	phosphoribosyl-ATP pyrophosphatase [Serratia fonticola].	41.05	95	56	0	24	118	17	111	1e-21	95.9
rs:WP_046409929	phosphoribosyl-ATP pyrophosphatase [Bacteroides sp. N54.MGS-20].	43.56	101	57	0	23	123	9	109	1e-21	95.9
rs:WP_010482583	phosphoribosyl-AMP cyclohydrolase [[Pseudomonas] geniculata].	44.44	99	50	1	24	122	22	115	1e-21	96.3
rs:WP_019989079	phosphoribosyl-AMP cyclohydrolase [Rudanella lutea].	43.43	99	54	1	16	112	2	100	1e-21	95.9
rs:WP_024591068	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Pseudoalteromonas].	43.01	93	53	0	20	112	13	105	1e-21	95.9
rs:WP_007580656	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas].	43.01	93	53	0	20	112	13	105	1e-21	95.9
rs:WP_002480423	phosphoribosyl-ATP diphosphatase [Staphylococcus simulans].	46.15	91	49	0	24	114	10	100	1e-21	96.3
rs:WP_019245779	phosphoribosyl-AMP cyclohydrolase [Candidatus Alistipes marseilloanorexicus].	42.16	102	52	1	18	112	2	103	1e-21	95.9
rs:WP_021118757	phosphoribosyl-ATP diphosphatase [Haemophilus parasuis].	46.07	89	48	0	25	113	13	101	1e-21	96.3
rs:WP_013940828	phosphoribosyl-AMP cyclohydrolase [Myxococcus fulvus].	46.53	101	52	2	13	112	2	101	1e-21	95.9
rs:WP_039659822	phosphoribosyl-ATP pyrophosphatase [Pantoea sp. MBLJ3].	43.16	95	54	0	24	118	17	111	1e-21	95.9
rs:WP_043397222	phosphoribosyl-ATP pyrophosphatase [Stenotrophomonas maltophilia].	44.44	99	50	1	24	122	22	115	1e-21	95.9
tr:W1X409_ECOLX	SubName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000313|EMBL:ETJ23454.1}; Flags: Fragment;	46.43	84	45	0	24	107	17	100	1e-21	93.2
rs:WP_024604211	phosphoribosyl-ATP pyrophosphatase [Pseudoalteromonas haloplanktis].	43.01	93	53	0	20	112	13	105	2e-21	95.9
rs:WP_033029702	phosphoribosyl-ATP pyrophosphatase [Pseudoalteromonas citrea].	43.01	93	53	0	20	112	13	105	2e-21	95.9
rs:WP_039640534	phosphoribosyl-ATP pyrophosphatase [Campylobacter lari].	40.45	89	53	0	24	112	19	107	2e-21	95.9
rs:WP_046652270	imidazole glycerol phosphate synthase [Brevundimonas diminuta].	42.02	119	63	1	11	123	1	119	2e-21	96.3
rs:WP_002612950	phosphoribosyl-AMP cyclohydrolase [Stigmatella aurantiaca].	46.60	103	53	2	11	112	1	102	2e-21	95.9
rs:WP_041834813	phosphoribosyl-ATP pyrophosphatase [Actinobacillus succinogenes].	44.94	89	49	0	25	113	12	100	2e-21	95.9
rs:WP_026838699	phosphoribosyl-ATP pyrophosphatase [Gillisia sp. JM1].	43.96	91	51	0	21	111	8	98	2e-21	95.9
tr:A6VQ75_ACTSZ	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	44.94	89	49	0	25	113	14	102	2e-21	96.3
rs:WP_007376299	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas].	43.01	93	53	0	20	112	13	105	2e-21	95.9
rs:WP_041192901	phosphoribosyl-ATP pyrophosphatase, partial [Candidatus Uzinura diaspidicola].	41.24	97	55	1	17	111	8	104	2e-21	95.9
tr:K4CXC5_SOLLC	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Solyc10g005930.1.1};	37.19	121	72	1	2	118	38	158	2e-21	96.3
rs:WP_043394592	phosphoribosyl-AMP cyclohydrolase [Cystobacter violaceus].	46.67	105	54	2	11	114	1	104	2e-21	95.9
rs:WP_034939548	phosphoribosyl-AMP cyclohydrolase [Candidatus Accumulibacter sp. SK-12].	48.57	105	53	1	17	120	13	117	2e-21	94.0
rs:WP_024597353	phosphoribosyl-ATP pyrophosphatase [Pseudoalteromonas haloplanktis].	43.01	93	53	0	20	112	13	105	2e-21	95.9
rs:WP_041844489	phosphoribosyl-ATP pyrophosphatase [Thermotoga sp. RQ7].	47.31	93	47	1	25	115	3	95	2e-21	95.5
rs:WP_022805933	phosphoribosyl-ATP pyrophosphatase [Calescamantes bacterium JGI 0000106-N5].	40.19	107	63	1	12	118	4	109	2e-21	96.3
rs:WP_010552953	phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas arctica].	43.01	93	53	0	20	112	13	105	2e-21	95.9
tr:B3DWX6_METI4	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	44.76	105	57	1	19	122	24	128	2e-21	94.4
tr:T1BZ76_9ZZZZ	SubName: Full=Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein {ECO:0000313|EMBL:EQD58339.1};	51.19	84	41	0	29	112	1	84	2e-21	95.5
rs:WP_011944126	phosphoribosyl-ATP pyrophosphatase [Thermotoga naphthophila].	47.31	93	47	1	25	115	3	95	2e-21	95.5
tr:L7VJF2_9FLAO	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	41.24	97	55	1	17	111	8	104	2e-21	96.3
tr:A7C638_9GAMM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	46.59	88	45	2	40	126	1	87	2e-21	93.2
rs:WP_002960271	phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas haloplanktis].	43.01	93	53	0	20	112	13	105	2e-21	95.9
rs:WP_038034147	MULTISPECIES: phosphoribosyl-ATP pyrophosphatase [Thermotoga].	47.31	93	47	1	25	115	3	95	2e-21	95.5
rs:WP_038067889	phosphoribosyl-ATP pyrophosphatase [Thermotoga neapolitana].	47.31	93	47	1	25	115	3	95	2e-21	95.5
tr:A1SVC4_PSYIN	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	43.82	89	50	0	24	112	21	109	2e-21	95.9
tr:B9K9S4_THENN	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	47.31	93	47	1	25	115	4	96	2e-21	95.5
rs:WP_005624684	phosphoribosyl-AMP cyclohydrolase [Actinobacillus ureae].	44.94	89	49	0	25	113	14	102	2e-21	95.9
rs:WP_037071020	phosphoribosyl-ATP pyrophosphatase [Psychromonas arctica].	39.36	94	57	0	24	117	16	109	2e-21	95.5
rs:WP_012311333	phosphoribosyl-ATP pyrophosphatase [Thermotoga sp. RQ2].	47.31	93	47	1	25	115	3	95	2e-21	95.5
rs:WP_034823005	phosphoribosyl-ATP pyrophosphatase [Idiomarina sp. 28-8].	44.44	90	50	0	23	112	17	106	2e-21	95.5
gp:AF067228_11	phosphoribosyl-AMP cyclohydrolase/ phosphoribosyl-ATP pyrophosphatase [Buchnera aphidicola]	42.22	90	52	0	24	113	18	107	2e-21	95.9
sp:HIS2_BUCAP	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	42.22	90	52	0	24	113	18	107	2e-21	95.5
rs:WP_045424359	phosphoribosyl-ATP pyrophosphatase [Edwardsiella piscicida].	44.94	89	49	0	24	112	22	110	2e-21	95.9
rs:WP_034758016	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium sp. OV259].	43.75	96	53	1	18	112	2	97	2e-21	95.5
rs:WP_047137250	phosphoribosyl-ATP pyrophosphatase [Luteimonas sp. FCS-9].	45.71	105	56	1	11	114	1	105	2e-21	95.5
rs:WP_041767081	phosphoribosyl-ATP pyrophosphatase [Psychromonas ingrahamii].	43.82	89	50	0	24	112	16	104	2e-21	95.5
rs:WP_033791521	phosphoribosyl-ATP pyrophosphatase [Pantoea sp. FF5].	44.21	95	53	0	24	118	17	111	2e-21	95.5
tr:F5S6A9_9NEIS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	56.58	76	33	0	16	91	6	81	2e-21	92.8
tr:A2VTG7_9BURK	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	49.43	87	40	2	44	126	1	87	2e-21	92.8
rs:WP_012849112	phosphoribosyl-AMP cyclohydrolase [Edwardsiella tarda].	44.94	89	49	0	24	112	22	110	2e-21	95.5
rs:WP_013099586	phosphoribosyl-AMP cyclohydrolase [Methanocaldococcus infernus].	47.37	95	49	1	25	119	15	108	2e-21	93.6
rs:WP_034162547	phosphoribosyl-ATP pyrophosphatase [Edwardsiella tarda].	44.94	89	49	0	24	112	22	110	2e-21	95.5
rs:WP_004080487	phosphoribosyl-ATP pyrophosphatase [Thermotoga maritima].	47.31	93	47	1	25	115	3	95	2e-21	95.5
rs:WP_033038392	phosphoribosyl-ATP pyrophosphatase [Pseudoalteromonas sp. S3431].	43.01	93	53	0	20	112	13	105	2e-21	95.5
rs:WP_026814001	phosphoribosyl-ATP pyrophosphatase [Arenibacter certesii].	45.05	91	50	0	21	111	8	98	2e-21	95.5
rs:WP_028975208	phosphoribosyl-AMP cyclohydrolase [Spirochaeta cellobiosiphila].	42.11	114	54	3	17	118	4	117	2e-21	93.6
rs:WP_019338506	phosphoribosyl-AMP cyclohydrolase [Stenotrophomonas maltophilia].	46.07	89	48	0	24	112	22	110	2e-21	95.5
tr:C2NWB3_BACCE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	52.70	74	35	0	40	113	1	74	2e-21	92.4
sp:HIS2_THEMA	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	47.31	93	47	1	25	115	4	96	2e-21	95.5
rs:WP_006363293	phosphoribosyl-AMP cyclohydrolase [Stenotrophomonas maltophilia].	46.07	89	48	0	24	112	22	110	2e-21	95.5
rs:WP_004095971	phosphoribosyl-AMP cyclohydrolase [Hafnia alvei].	43.30	97	55	0	24	120	22	118	2e-21	95.5
rs:WP_005409432	phosphoribosyl-AMP cyclohydrolase [Stenotrophomonas maltophilia].	46.07	89	48	0	24	112	22	110	2e-21	95.5
rs:WP_012510888	phosphoribosyl-AMP cyclohydrolase [Stenotrophomonas maltophilia].	46.07	89	48	0	24	112	22	110	2e-21	95.5
rs:WP_019661420	phosphoribosyl-AMP cyclohydrolase [Stenotrophomonas maltophilia].	46.07	89	48	0	24	112	22	110	2e-21	95.5
rs:WP_024594330	phosphoribosyl-ATP pyrophosphatase [Pseudoalteromonas haloplanktis].	43.01	93	53	0	20	112	13	105	2e-21	95.5
rs:WP_017550018	hypothetical protein [Salinicoccus carnicancri].	46.67	90	48	0	23	112	9	98	2e-21	95.5
rs:WP_031503348	hypothetical protein [Pseudothermotoga hypogea].	46.81	94	48	1	25	116	9	102	2e-21	95.5
rs:WP_012480037	phosphoribosyl-AMP cyclohydrolase [Stenotrophomonas maltophilia].	46.07	89	48	0	24	112	22	110	2e-21	95.5
rs:WP_033298378	phosphoribosyl-ATP pyrophosphatase [Psychromonas ossibalaenae].	41.57	89	52	0	24	112	16	104	2e-21	95.5
rs:WP_021093340	phosphoribosyl-AMP cyclohydrolase [Campylobacter concisus].	46.74	92	48	1	24	114	15	106	2e-21	96.3
rs:WP_034362834	phosphoribosyl-ATP diphosphatase [Helicobacter sp. MIT 01-6451].	43.82	89	50	0	25	113	15	103	2e-21	95.9
tr:A0A084SVZ2_9DELT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	46.60	103	53	2	13	114	2	103	3e-21	95.5
rs:WP_031476332	phosphoribosyl-AMP cyclohydrolase [Eubacterium desmolans].	45.26	95	52	0	20	114	7	101	3e-21	92.8
rs:WP_014037012	phosphoribosyl-AMP cyclohydrolase [Stenotrophomonas maltophilia].	46.07	89	48	0	24	112	22	110	3e-21	95.5
tr:C3IGX1_BACTU	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	54.05	74	34	0	40	113	1	74	3e-21	92.0
rs:WP_020031306	MULTISPECIES: hypothetical protein [unclassified Gammaproteobacteria (miscellaneous)].	39.00	100	61	0	13	112	1	100	3e-21	95.1
rs:WP_010617674	phosphoribosyl-AMP cyclohydrolase [Plautia stali symbiont].	43.75	96	54	0	23	118	16	111	3e-21	95.1
rs:WP_024528604	phosphoribosyl-ATP pyrophosphatase [Serratia fonticola].	44.44	90	50	0	24	113	17	106	3e-21	95.1
rs:WP_004241707	phosphoribosyl-AMP cyclohydrolase [Morganella morganii].	46.59	88	47	0	25	112	18	105	3e-21	95.1
tr:A0A0A7V6C4_9ARCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	39.56	91	55	0	24	114	16	106	3e-21	92.8
rs:WP_046024230	phosphoribosyl-ATP pyrophosphatase [Morganella morganii].	46.59	88	47	0	25	112	18	105	3e-21	95.1
rs:WP_046358796	phosphoribosyl-ATP pyrophosphatase [Hafnia alvei].	43.30	97	55	0	24	120	22	118	3e-21	95.1
tr:C2X992_BACCE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	52.70	74	35	0	40	113	1	74	3e-21	92.0
rs:WP_015871850	phosphoribosyl-AMP cyclohydrolase [Edwardsiella ictaluri].	45.45	88	48	0	25	112	23	110	3e-21	95.1
rs:WP_040045836	phosphoribosyl-ATP pyrophosphatase [Hafnia alvei].	43.30	97	55	0	24	120	22	118	3e-21	95.1
rs:WP_037217390	phosphoribosyl-AMP cyclohydrolase, partial [Richelia intracellularis].	56.00	75	33	0	19	93	23	97	3e-21	92.4
tr:A0A075HVY0_9ARCH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000256|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000256|HAMAP-Rule:MF_01021};	39.56	91	55	0	24	114	16	106	3e-21	92.8
rs:WP_023015823	phosphoribosyl-AMP cyclohydrolase [Staphylococcus simulans].	45.05	91	50	0	24	114	10	100	3e-21	95.1
rs:WP_014246339	phosphoribosyl-AMP cyclohydrolase [Blattabacterium punctulatus].	37.62	101	62	1	11	111	1	100	3e-21	95.1
rs:WP_004256466	phosphoribosyl-AMP cyclohydrolase [Providencia rettgeri].	44.94	89	49	0	24	112	17	105	3e-21	95.1
rs:WP_014347819	phosphoribosyl-AMP cyclohydrolase [Pyrobaculum oguniense].	55.13	78	35	0	35	112	47	124	3e-21	93.6
rs:WP_043492165	phosphoribosyl-ATP pyrophosphatase [Hafnia alvei].	43.30	97	55	0	24	120	22	118	3e-21	95.1
rs:WP_014396526	phosphoribosyl-AMP cyclohydrolase [Corallococcus coralloides].	45.63	103	54	2	11	112	1	102	3e-21	95.1
rs:WP_046791295	phosphoribosyl-ATP pyrophosphatase [Salinicoccus halodurans].	45.56	90	49	0	23	112	9	98	3e-21	95.1
rs:WP_046458046	phosphoribosyl-ATP pyrophosphatase [Hafnia alvei].	43.30	97	55	0	24	120	22	118	3e-21	95.1
rs:WP_033833300	phosphoribosyl-ATP pyrophosphatase [Stenotrophomonas maltophilia].	44.21	95	53	0	24	118	22	116	3e-21	95.1
tr:C3G0D9_BACTU	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	52.70	74	35	0	40	113	1	74	3e-21	91.7
rs:WP_004235765	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Morganella].	46.59	88	47	0	25	112	18	105	3e-21	95.1
rs:WP_025800863	phosphoribosyl-ATP pyrophosphatase [Hafnia alvei].	43.30	97	55	0	24	120	22	118	3e-21	95.1
rs:WP_033733216	phosphoribosyl-ATP pyrophosphatase [Pantoea vagans].	38.46	117	66	1	2	118	1	111	3e-21	95.1
rs:WP_028866029	phosphoribosyl-ATP pyrophosphatase [Psychromonas aquimarina].	42.05	88	51	0	25	112	22	109	3e-21	95.1
rs:WP_004586385	phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas agarivorans].	43.01	93	53	0	20	112	13	105	3e-21	95.1
rs:WP_013478330	phosphoribosyl-AMP cyclohydrolase [Asticcacaulis excentricus].	48.00	100	51	1	14	112	15	114	3e-21	95.1
tr:M0ZZU7_SOLTU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:PGSC0003DMT400011613};	37.19	121	72	1	2	118	38	158	4e-21	96.3
tr:C2MYA4_BACCE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	52.70	74	35	0	40	113	1	74	4e-21	91.7
rs:XP_004248357	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic [Solanum lycopersicum].	37.19	121	72	1	2	118	38	158	4e-21	96.3
rs:WP_012821357	phosphoribosyl-AMP cyclohydrolase [Blattabacterium sp. (Periplaneta americana)].	43.68	87	49	0	25	111	15	101	4e-21	94.7
tr:C2NF21_BACCE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	52.70	74	35	0	40	113	1	74	4e-21	91.7
tr:C3EZ21_BACTU	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	52.70	74	35	0	40	113	1	74	4e-21	91.7
rs:WP_035124817	phosphoribosyl-ATP pyrophosphatase [Flavobacterium aquatile].	43.96	91	51	0	24	114	10	100	4e-21	94.7
rs:WP_044186874	phosphoribosyl-AMP cyclohydrolase [Hyalangium minutum].	45.63	103	54	2	11	112	1	102	4e-21	94.7
rs:WP_026865866	phosphoribosyl-ATP pyrophosphatase [Jeotgalicoccus marinus].	46.59	88	47	0	25	112	11	98	4e-21	94.7
tr:J9GZ56_9ZZZZ	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:EJX06180.1}; EC=3.5.4.19 {ECO:0000313|EMBL:EJX06180.1};	40.19	107	63	1	15	120	24	130	5e-21	93.6
rs:WP_019167079	phosphoribosyl-AMP cyclohydrolase [Staphylococcus delphini].	43.96	91	51	0	24	114	10	100	5e-21	94.7
rs:XP_009804268	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic [Nicotiana sylvestris].	38.53	109	67	0	9	117	49	157	5e-21	95.9
rs:WP_015370803	phosphoribosyl-AMP cyclohydrolase [Blattabacterium sp. (Blatta orientalis)].	43.68	87	49	0	25	111	15	101	5e-21	94.7
rs:WP_039627721	phosphoribosyl-ATP pyrophosphatase [Campylobacter lari].	40.45	89	53	0	24	112	19	107	5e-21	94.7
rs:WP_035178348	phosphoribosyl-AMP cyclohydrolase [Lactobacillus farraginis].	53.25	77	36	0	40	116	1	77	5e-21	91.3
rs:XP_005647330	PRA-CH-domain-containing protein [Coccomyxa subellipsoidea C-169].	45.00	100	55	0	17	116	7	106	5e-21	95.1
rs:WP_040995276	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium oranimense].	42.71	96	54	1	18	112	3	98	5e-21	94.4
rs:WP_005492651	phosphoribosyl-AMP cyclohydrolase [Pseudoalteromonas luteoviolacea].	45.16	93	51	0	20	112	13	105	5e-21	94.4
rs:WP_036974676	phosphoribosyl-ATP pyrophosphatase [Providencia alcalifaciens].	44.94	89	49	0	24	112	17	105	6e-21	94.4
rs:WP_042148443	phosphoribosyl-ATP pyrophosphatase [Pseudoalteromonas sp. '520P1 No. 412'].	40.95	105	59	1	11	112	1	105	6e-21	94.4
rs:WP_046519547	phosphoribosyl-ATP pyrophosphatase [Rheinheimera sp. IITR-13].	44.44	90	50	0	24	113	18	107	6e-21	94.7
rs:WP_027419484	phosphoribosyl-ATP pyrophosphatase [Crocinitomix catalasitica].	41.67	96	56	0	24	119	10	105	6e-21	94.4
rs:XP_009613200	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic [Nicotiana tomentosiformis].	38.53	109	67	0	9	117	49	157	6e-21	95.5
rs:WP_046985962	phosphoribosyl-ATP pyrophosphatase [Thermomonas brevis].	43.43	99	51	1	24	122	22	115	6e-21	94.4
rs:WP_032129950	phosphoribosyl-ATP pyrophosphatase [Stenotrophomonas maltophilia].	44.21	95	53	0	24	118	22	116	6e-21	94.4
rs:WP_013799582	phosphoribosyl-AMP cyclohydrolase [Methanotorris igneus].	47.37	95	49	1	25	119	24	117	6e-21	92.4
rs:XP_005849799	hypothetical protein CHLNCDRAFT_20847 [Chlorella variabilis].	46.67	105	49	2	17	114	7	111	6e-21	95.1
tr:A0A0A9DIG7_ARUDO	SubName: Full=Histidine biosynthesis bifunctional protein hisIE {ECO:0000313|EMBL:JAD87576.1};	40.52	116	65	1	8	119	111	226	6e-21	95.5
tr:A0A078M8G3_9STAP	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	44.94	89	49	0	24	112	10	98	6e-21	94.4
tr:A0A0A9GCV3_ARUDO	SubName: Full=Histidine biosynthesis bifunctional protein hisIE {ECO:0000313|EMBL:JAE20381.1};	40.52	116	65	1	8	119	111	226	6e-21	95.9
tr:I0R0E7_9MICO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	42.11	95	55	0	18	112	9	103	6e-21	91.7
rs:XP_006305506	hypothetical protein CARUB_v10009971mg [Capsella rubella].	39.09	110	67	0	9	118	47	156	7e-21	95.5
rs:WP_008489195	phosphoribosyl-AMP cyclohydrolase [Idiomarina xiamenensis].	42.86	105	59	1	9	112	7	111	7e-21	94.4
tr:A0A085WPF2_9DELT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	45.54	101	53	2	13	112	2	101	7e-21	94.4
rs:XP_008465390	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic [Cucumis melo].	41.58	101	59	0	18	118	55	155	7e-21	95.5
rs:WP_018577012	phosphoribosyl-AMP cyclohydrolase [Legionella shakespearei].	44.94	89	49	0	24	112	16	104	7e-21	94.4
rs:WP_037499884	phosphoribosyl-ATP pyrophosphatase [Sphingomonas jaspsi].	44.55	101	55	1	13	112	2	102	7e-21	94.0
rs:WP_029293258	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium hispalense].	39.32	117	61	2	17	123	2	118	7e-21	94.0
tr:W4LKG8_9DELT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	37.04	135	73	4	1	124	1	134	8e-21	92.4
rs:XP_007161596	hypothetical protein PHAVU_001G082700g [Phaseolus vulgaris].	38.60	114	70	0	5	118	41	154	8e-21	95.1
rs:WP_047099206	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium indologenes].	43.82	89	50	0	24	112	10	98	8e-21	94.0
rs:WP_031591333	phosphoribosyl-ATP pyrophosphatase [Pantoea agglomerans].	43.16	95	54	0	24	118	17	111	8e-21	94.0
tr:W1YGE6_9ZZZZ	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:ETJ40244.1}; Flags: Fragment;	53.33	75	35	0	43	117	1	75	8e-21	90.9
rs:WP_011554225	phosphoribosyl-AMP cyclohydrolase [Myxococcus xanthus].	46.53	101	52	2	13	112	2	101	9e-21	94.0
rs:WP_002979668	phosphoribosyl-AMP cyclohydrolase [Chryseobacterium gleum].	39.66	116	60	2	18	123	3	118	9e-21	93.6
rs:XP_001693537	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase [Chlamydomonas reinhardtii].	38.79	116	71	0	2	117	56	171	9e-21	95.1
rs:WP_035809822	phosphoribosyl-ATP pyrophosphatase [Jeotgalicoccus sp. 13MG44_air].	44.94	89	49	0	24	112	16	104	9e-21	94.0
rs:WP_031375352	phosphoribosyl-ATP pyrophosphatase [Pantoea sp. 3.5.1].	44.94	89	49	0	24	112	17	105	9e-21	94.0
rs:WP_031495909	phosphoribosyl-AMP cyclohydrolase [Bryobacter aggregatus].	45.56	90	48	1	24	112	11	100	9e-21	92.0
rs:WP_011235073	phosphoribosyl-AMP cyclohydrolase [Idiomarina loihiensis].	43.33	90	51	0	23	112	17	106	9e-21	93.6
rs:WP_009089305	phosphoribosyl-AMP cyclohydrolase [Pantoea sp. Sc1].	43.82	89	50	0	24	112	17	105	1e-20	93.6
rs:XP_002893693	AT-IE [Arabidopsis lyrata subsp. lyrata].	40.59	101	60	0	18	118	59	159	1e-20	94.7
rs:WP_032355133	hypothetical protein, partial [Shigella flexneri].	48.10	79	41	0	24	102	17	95	1e-20	90.9
rs:XP_008349767	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic-like [Malus domestica].	41.18	102	60	0	17	118	23	124	1e-20	94.4
rs:WP_046513032	phosphoribosyl-ATP pyrophosphatase [Salinicoccus sp. SV-16].	46.67	90	48	0	23	112	9	98	1e-20	93.6
rs:WP_007043481	phosphoribosyl-AMP cyclohydrolase [Methanotorris formicicus].	46.32	95	50	1	25	119	23	116	1e-20	91.7
tr:A0A078JKV4_BRANA	SubName: Full=BnaA05g36290D protein {ECO:0000313|EMBL:CDY67070.1}; Flags: Fragment;	41.58	101	59	0	18	118	8	108	1e-20	94.0
rs:WP_037440354	phosphoribosyl-ATP pyrophosphatase [Shewanella sp. YQH10].	38.66	119	62	2	3	121	5	112	1e-20	93.6
tr:A0A0A7FZX5_9CLOT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	48.65	74	38	0	40	113	1	74	1e-20	90.5
tr:C4S1F9_YERBE	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	46.43	84	45	0	35	118	2	85	1e-20	92.8
rs:WP_011283010	phosphoribosyl-AMP cyclohydrolase [Candidatus Blochmannia pennsylvanicus].	43.33	90	51	0	24	113	17	106	1e-20	93.6
rs:WP_033772190	phosphoribosyl-ATP pyrophosphatase [Pantoea agglomerans].	43.16	95	54	0	24	118	17	111	1e-20	93.6
rs:WP_037049953	phosphoribosyl-ATP pyrophosphatase [Psychromonas sp. SP041].	37.38	107	62	1	24	130	16	117	1e-20	93.6
rs:WP_047207869	phosphoribosyl-ATP pyrophosphatase [Campylobacter lari].	39.33	89	54	0	24	112	19	107	1e-20	93.6
rs:XP_004143768	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic [Cucumis sativus].	41.58	101	59	0	18	118	55	155	1e-20	94.4
rs:WP_039617198	phosphoribosyl-ATP pyrophosphatase [Campylobacter lari].	39.33	89	54	0	24	112	19	107	1e-20	93.6
rs:WP_003555185	phosphoribosyl-AMP cyclohydrolase [Lactobacillus brevis].	51.95	77	37	0	40	116	1	77	1e-20	90.5
rs:WP_015344716	histidine biosynthesis bifunctional protein HisIE [Candidatus Blochmannia chromaiodes].	43.33	90	51	0	24	113	17	106	1e-20	93.6
rs:WP_034676305	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium formosense].	43.48	92	52	0	21	112	8	99	1e-20	93.2
rs:WP_014499831	phosphoribosyl-AMP cyclohydrolase [Buchnera aphidicola].	42.70	89	51	0	24	112	17	105	1e-20	93.2
tr:S2RDD8_LACPA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	46.43	84	45	0	38	121	1	84	1e-20	90.5
rs:XP_009342342	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic-like [Pyrus x bretschneideri].	41.18	102	60	0	17	118	65	166	2e-20	94.4
tr:C2PCD1_BACCE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	52.70	74	35	0	40	113	1	74	2e-20	90.1
rs:WP_013180739	phosphoribosyl-AMP cyclohydrolase [Methanococcus voltae].	44.86	107	54	3	17	119	12	117	2e-20	91.3
rs:WP_014799461	phosphoribosyl-AMP cyclohydrolase [Flexibacter litoralis].	37.61	109	62	1	4	112	5	107	2e-20	93.6
rs:XP_003057704	predicted protein [Micromonas pusilla CCMP1545].	43.81	105	57	1	18	120	17	121	2e-20	94.0
rs:WP_006812660	phosphoribosyl-AMP cyclohydrolase [Providencia rustigianii].	44.94	89	49	0	24	112	17	105	2e-20	93.2
rs:WP_039344073	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium solincola].	44.94	89	49	0	24	112	10	98	2e-20	93.2
rs:WP_035310027	imidazole glycerol phosphate synthase [Brevundimonas sp. EAKA].	40.71	113	66	1	13	124	2	114	2e-20	93.2
tr:X1AIT0_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_S00116 {ECO:0000313|EMBL:GAG82009.1}; Flags: Fragment;	35.66	129	56	1	20	121	12	140	2e-20	91.7
rs:WP_042723103	phosphoribosyl-ATP pyrophosphatase [Flavobacterium sp. B17].	42.39	92	53	0	21	112	8	99	2e-20	92.8
tr:A0A0D3CGX0_BRAOL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Bo5g091860.1};	41.58	101	59	0	18	118	57	157	2e-20	94.4
rs:WP_022565241	histidine biosynthesis bifunctional protein HisIE [Blattabacterium sp. (Nauphoeta cinerea)].	43.68	87	49	0	25	111	10	96	2e-20	92.8
rs:XP_009145226	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic-like [Brassica rapa].	41.58	101	59	0	18	118	59	159	2e-20	94.4
tr:A0A0A9QFX5_ARUDO	SubName: Full=Histidine biosynthesis bifunctional protein hisIE {ECO:0000313|EMBL:JAF33448.1};	40.20	102	61	0	17	118	69	170	2e-20	92.4
tr:C2MI77_BACCE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	51.35	74	36	0	40	113	1	74	2e-20	89.7
rs:WP_039368478	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium taiwanense].	43.62	94	52	1	20	112	5	98	2e-20	92.8
sp:HIS2_ARATH	RecName: Full=Histidine biosynthesis bifunctional protein hisIE, chloroplastic; AltName: Full=Protein HISTIDINE BIOSYNTHESIS 2; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31; Flags: Precursor;	39.60	101	61	0	18	118	59	159	2e-20	94.4
rs:WP_039348146	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium jeonii].	40.37	109	56	1	24	123	10	118	2e-20	92.8
tr:A0A087HS48_ARAAL	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFK44950.1};	40.59	101	60	0	18	118	53	153	2e-20	94.0
rs:WP_042846547	phosphoribosyl-ATP pyrophosphatase [Providencia rettgeri].	43.82	89	50	0	24	112	17	105	2e-20	93.2
rs:XP_010478608	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic-like [Camelina sativa].	40.20	102	61	0	17	118	55	156	2e-20	94.0
rs:XP_010499736	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic [Camelina sativa].	40.20	102	61	0	17	118	55	156	2e-20	94.0
rs:WP_011672467	phosphoribosyl-AMP cyclohydrolase [Buchnera aphidicola].	40.19	107	57	1	24	123	17	123	2e-20	93.2
rs:WP_021202827	phosphoribosyl-AMP cyclohydrolase [Stenotrophomonas maltophilia].	43.16	95	54	0	24	118	22	116	2e-20	93.2
rs:WP_044205417	phosphoribosyl-AMP cyclohydrolase [Flammeovirga sp. OC4].	37.76	98	54	2	23	113	23	120	2e-20	91.3
rs:WP_006657677	phosphoribosyl-AMP cyclohydrolase [Providencia alcalifaciens].	44.94	89	49	0	24	112	17	105	2e-20	92.8
gpu:CP011805_850	phosphoribosyl-AMP cyclohydrolase [Altererythrobacter marensis]	43.16	95	54	0	19	113	8	102	2e-20	90.9
rs:WP_004909325	phosphoribosyl-AMP cyclohydrolase [Providencia rettgeri].	43.82	89	50	0	24	112	17	105	2e-20	92.8
rs:WP_035336676	phosphoribosyl-ATP pyrophosphatase [Dokdonia sp. PRO95].	44.44	90	50	0	22	111	9	98	2e-20	92.8
tr:C2Q9E8_BACCE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	51.35	74	36	0	40	113	1	74	2e-20	89.7
tr:O30625_ECOLX	SubName: Full=Phosphoribosyl-ATP pyrophosphohydrolase/phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:AAC45842.1}; Flags: Fragment;	48.05	77	40	0	36	112	1	77	2e-20	92.0
tr:A9NSD7_PICSI	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:ABK23548.1};	41.18	102	60	0	17	118	97	198	3e-20	94.0
rs:WP_025368753	phosphoribosyl-ATP pyrophosphatase [Buchnera aphidicola].	40.45	89	53	0	24	112	17	105	3e-20	92.8
rs:WP_020006476	hypothetical protein [Salinicoccus albus].	44.44	90	50	0	23	112	9	98	3e-20	92.8
rs:WP_034925476	phosphoribosyl-ATP pyrophosphatase [Gillisia sp. CAL575].	41.76	91	53	0	21	111	8	98	3e-20	92.8
rs:WP_034731231	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium sp. JM1].	41.67	96	55	1	18	112	3	98	3e-20	92.4
rs:WP_013044675	phosphoribosyl-AMP cyclohydrolase [Coraliomargarita akajimensis].	41.03	117	59	3	7	113	8	124	3e-20	91.3
tr:W0RED7_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	47.52	101	51	2	13	112	2	101	3e-20	92.8
rs:XP_010104402	Histidine biosynthesis bifunctional protein hisIE [Morus notabilis].	40.00	105	63	0	17	121	57	161	3e-20	93.6
tr:C2Z5B6_BACCE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	51.35	74	36	0	40	113	1	74	3e-20	89.4
rs:WP_008261513	phosphoribosyl-AMP cyclohydrolase [Brevundimonas sp. BAL3].	39.82	113	67	1	13	124	2	114	3e-20	92.4
rs:WP_013751955	phosphoribosyl-AMP cyclohydrolase [Dokdonia sp. 4H-3-7-5].	43.33	90	51	0	22	111	9	98	3e-20	92.4
rs:WP_040913741	phosphoribosyl-AMP cyclohydrolase [Leptospira kmetyi].	39.84	123	71	2	10	130	60	181	3e-20	92.0
rs:WP_013775943	phosphoribosyl-AMP cyclohydrolase [Acidianus hospitalis].	44.09	93	52	0	21	113	23	115	3e-20	90.5
rs:WP_044832508	phosphoribosyl-ATP pyrophosphatase [Thalassomonas actiniarum].	45.56	90	49	0	23	112	17	106	3e-20	92.4
rs:WP_031545998	phosphoribosyl-ATP pyrophosphatase [Salinicoccus luteus].	45.56	90	49	0	23	112	9	98	3e-20	92.4
rs:WP_014345394	phosphoribosyl-AMP cyclohydrolase [Sulfobacillus acidophilus].	44.00	100	56	0	25	124	11	110	3e-20	92.4
rs:WP_020989115	phosphoribosyl-AMP cyclohydrolase [Leptospira inadai].	40.74	108	63	1	6	113	55	161	3e-20	92.0
tr:C2S180_BACCE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	51.35	74	36	0	40	113	1	74	3e-20	89.4
rs:WP_034694431	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium sp. CF365].	38.79	116	61	2	18	123	3	118	4e-20	92.0
tr:A0A0A9K0C4_ARUDO	SubName: Full=Histidine biosynthesis bifunctional protein hisIE {ECO:0000313|EMBL:JAE63233.1};	39.81	103	62	0	17	119	68	170	4e-20	92.4
rs:XP_012067380	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic [Jatropha curcas].	39.05	105	64	0	17	121	64	168	4e-20	93.2
tr:V6HQD3_9LEPT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	39.84	123	71	2	10	130	79	200	4e-20	92.0
gpu:CP011770_439	phosphoribosyl-AMP cyclohydrolase [Croceicoccus naphthovorans]	43.00	100	56	1	19	117	20	119	4e-20	91.3
rs:XP_002508182	predicted protein [Micromonas sp. RCC299].	41.90	105	59	1	18	120	17	121	4e-20	92.8
rs:WP_023461975	phosphoribosyl-AMP cyclohydrolase [Asticcacaulis sp. YBE204].	47.00	100	52	1	14	112	15	114	4e-20	92.4
tr:A0A086F6L1_9FLAO	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	42.71	96	54	1	18	112	3	98	4e-20	92.0
rs:WP_005434340	phosphoribosyl-AMP cyclohydrolase [Sutterella wadsworthensis].	41.51	106	61	1	18	122	7	112	4e-20	90.1
gpu:CP009928_3261	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium gallinarum]	42.71	96	54	1	18	112	3	98	4e-20	92.0
rs:WP_024956879	phosphoribosyl-ATP pyrophosphatase [Stenotrophomonas maltophilia].	43.16	95	54	0	24	118	22	116	4e-20	92.0
rs:WP_015429819	bifunctional phosphoribosyl-AMP [Blattabacterium sp. (Panesthia angustipennis spadica)].	38.89	90	55	0	22	111	5	94	4e-20	91.7
gpu:CP010904_571	phosphoribosyl-AMP cyclohydrolase [Verrucomicrobia bacterium L21-Fru-AB]	35.66	129	74	3	1	120	1	129	5e-20	90.5
tr:A0A078FGZ3_BRANA	SubName: Full=BnaA09g24740D protein {ECO:0000313|EMBL:CDY12274.1};	40.59	101	60	0	18	118	60	160	5e-20	92.8
rs:WP_033767786	phosphoribosyl-ATP pyrophosphatase [Pantoea agglomerans].	42.11	95	55	0	24	118	17	111	5e-20	92.0
rs:XP_009114944	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic-like [Brassica rapa].	40.59	101	60	0	18	118	62	162	5e-20	92.8
rs:WP_034302122	phosphoribosyl-ATP pyrophosphatase [Alkalibacterium sp. AK22].	41.57	89	52	0	24	112	14	102	5e-20	92.0
tr:K1Z1S8_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019, ECO:0000256|SAAS:SAAS00015509};	39.33	89	54	0	24	112	16	104	5e-20	91.7
rs:XP_007514309	predicted protein [Bathycoccus prasinos].	38.60	114	69	1	17	130	89	201	5e-20	93.2
rs:WP_046288929	phosphoribosyl-ATP pyrophosphatase [Blochmannia endosymbiont of Polyrhachis (Hedomyrma) turneri].	41.05	95	56	0	24	118	3	97	5e-20	91.7
rs:WP_013409110	phosphoribosyl-AMP cyclohydrolase [Leadbetterella byssophila].	42.05	88	51	0	24	111	10	97	5e-20	91.7
rs:WP_032254392	phosphoribosyl-ATP pyrophosphatase, partial [Escherichia coli].	46.15	78	42	0	35	112	1	78	5e-20	91.3
rs:WP_015899884	phosphoribosyl-AMP cyclohydrolase [Staphylococcus carnosus].	43.69	103	55	1	24	123	10	112	6e-20	91.7
rs:WP_033778806	phosphoribosyl-ATP pyrophosphatase [Pantoea agglomerans].	42.11	95	55	0	24	118	17	111	6e-20	91.7
rs:WP_003561506	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Lactobacillus].	50.65	77	38	0	40	116	1	77	6e-20	88.6
rs:WP_023449307	phosphoribosyl-AMP cyclohydrolase [Asticcacaulis sp. AC402].	45.00	100	54	1	14	112	15	114	6e-20	91.7
rs:WP_045496467	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium sp. StRB126].	40.37	109	56	1	24	123	10	118	6e-20	91.3
rs:WP_010670963	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Pantoea].	42.11	95	55	0	24	118	17	111	6e-20	91.7
rs:WP_034716464	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium antarcticum].	40.37	109	56	1	24	123	10	118	6e-20	91.3
rs:WP_006272630	phosphoribosyl-AMP cyclohydrolase [Asticcacaulis biprosthecium].	45.00	100	54	1	14	112	15	114	6e-20	91.7
rs:WP_041402872	phosphoribosyl-AMP cyclohydrolase, partial [Salinispira pacifica].	41.35	104	53	2	23	118	15	118	7e-20	89.4
tr:T0FDM5_9LEPT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	40.34	119	68	3	14	131	67	183	7e-20	90.9
rs:WP_034706001	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium luteum].	40.62	96	56	1	18	112	3	98	7e-20	91.3
rs:WP_014726518	phosphoribosyl-AMP cyclohydrolase [Blattabacterium sp. (Blaberus giganteus)].	40.00	90	54	0	22	111	5	94	8e-20	91.3
rs:WP_017504400	phosphoribosyl-AMP cyclohydrolase [alpha proteobacterium L41A].	39.82	113	67	1	13	124	2	114	8e-20	91.3
rs:XP_010264898	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic-like [Nelumbo nucifera].	40.20	102	61	0	17	118	52	153	8e-20	92.4
rs:WP_039244198	imidazole glycerol phosphate synthase [Brevundimonas nasdae].	40.18	112	66	1	13	123	2	113	8e-20	91.3
rs:WP_040911728	phosphoribosyl-AMP cyclohydrolase [Leptospira broomii].	40.34	119	68	3	14	131	64	180	8e-20	90.9
tr:A0A0E0JH15_ORYPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OPUNC01G11020.1};	39.81	103	62	0	16	118	83	185	8e-20	92.4
rs:XP_004493105	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic [Cicer arietinum].	39.60	101	61	0	18	118	56	156	8e-20	92.4
rs:WP_018625527	hypothetical protein [Kangiella aquimarina].	45.36	97	53	0	16	112	222	318	8e-20	93.2
rs:WP_040106305	phosphoribosyl-ATP pyrophosphatase [Salinicoccus roseus].	44.44	90	50	0	23	112	9	98	8e-20	91.3
rs:WP_011858179	phosphoribosyl-ATP diphosphatase [Acinetobacter baumannii].	52.00	75	35	1	40	113	1	75	8e-20	91.7
tr:A0A072U2X9_MEDTR	SubName: Full=Histidine biosynthesis hisIE protein {ECO:0000313|EMBL:KEH23503.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:KEH23503};	37.72	114	71	0	5	118	43	156	9e-20	92.4
rs:WP_016751154	phosphoribosyl-AMP cyclohydrolase [Leptospira kirschneri].	40.91	110	62	2	6	113	56	164	9e-20	90.9
rs:WP_033079480	phosphoribosyl-ATP pyrophosphatase [Thalassotalea sp. ND16A].	44.94	89	49	0	24	112	18	106	9e-20	91.3
rs:WP_004755506	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Leptospira].	40.91	110	62	2	6	113	56	164	9e-20	90.9
rs:XP_006598753	PREDICTED: uncharacterized protein LOC100807276 isoform X1 [Glycine max].	39.22	102	62	0	17	118	53	154	9e-20	92.0
rs:XP_006370154	Histidine biosynthesis bifunctional protein hisIE [Populus trichocarpa].	37.27	110	69	0	17	126	64	173	9e-20	92.0
rs:WP_008900606	phosphoribosyl-AMP cyclohydrolase [Rheinheimera sp. A13L].	43.33	90	51	0	24	113	18	107	1e-19	91.3
tr:V5WIP8_9SPIO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	39.29	112	60	2	23	126	38	149	1e-19	90.9
rs:WP_047131707	phosphoribosyl-ATP pyrophosphatase [Staphylococcus condimenti].	44.09	93	52	0	24	116	10	102	1e-19	91.3
rs:WP_036951929	phosphoribosyl-ATP pyrophosphatase [Providencia alcalifaciens].	44.94	89	49	0	24	112	17	105	1e-19	90.9
rs:XP_004493104	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic-like isoform X1 [Cicer arietinum].	39.60	101	61	0	18	118	81	181	1e-19	92.4
rs:WP_012681623	phosphoribosyl-AMP cyclohydrolase [Gemmatimonas aurantiaca].	46.67	105	52	3	9	112	3	104	1e-19	91.3
rs:WP_022921657	phosphoribosyl-AMP cyclohydrolase [Ornithinimicrobium pekingense].	43.48	92	52	0	21	112	19	110	1e-19	90.9
rs:XP_008359021	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic [Malus domestica].	40.00	105	63	0	17	121	64	168	1e-19	92.0
rs:XP_012437199	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic-like isoform X2 [Gossypium raimondii].	36.27	102	65	0	17	118	18	119	1e-19	89.4
rs:WP_028256805	phosphoribosyl-AMP cyclohydrolase [Verrucomicrobia bacterium SCGC AAA164-E04].	43.97	116	58	1	17	125	23	138	1e-19	89.7
rs:XP_002443519	hypothetical protein SORBIDRAFT_08g020870 [Sorghum bicolor].	39.81	103	62	0	17	119	82	184	1e-19	92.0
tr:X4BPS2_SALEN	SubName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000313|EMBL:AHT07031.1}; EC=3.5.4.19 {ECO:0000313|EMBL:AHT07031.1}; EC=3.6.1.31 {ECO:0000313|EMBL:AHT07031.1}; Flags: Fragment;	54.41	68	31	0	24	91	17	84	1e-19	87.8
rs:WP_008210760	phosphoribosyl-AMP cyclohydrolase [Lactobacillus parafarraginis].	50.65	77	38	0	40	116	1	77	1e-19	87.8
tr:A0A022PQD4_ERYGU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EYU17674.1};	35.45	110	71	0	17	126	49	158	1e-19	91.7
rs:WP_002693440	phosphoribosyl-AMP cyclohydrolase [Microscilla marina].	41.35	104	54	2	23	119	19	122	1e-19	89.0
rs:WP_027379386	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium daeguense].	43.33	90	51	0	23	112	9	98	1e-19	90.5
rs:WP_027082701	phosphoribosyl-ATP pyrophosphatase [Lysobacter sp. URHA0019].	41.03	117	66	2	13	128	7	121	1e-19	90.9
rs:XP_009358243	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic-like isoform X2 [Pyrus x bretschneideri].	39.05	105	64	0	17	121	64	168	1e-19	91.3
tr:A0A072UCD1_MEDTR	SubName: Full=Histidine biosynthesis hisIE protein {ECO:0000313|EMBL:KEH23505.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:KEH23505};	40.20	102	61	0	17	118	41	142	1e-19	91.7
rs:WP_016520645	phosphoribosyl-ATP diphosphatase [Treponema socranskii].	46.32	95	50	1	18	112	244	337	1e-19	92.8
tr:I1NM72_ORYGL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ORGLA01G0096200.1};	39.81	103	62	0	17	119	84	186	2e-19	91.7
rs:XP_010061389	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic [Eucalyptus grandis].	37.25	102	64	0	17	118	59	160	2e-19	91.7
tr:A0A0E0FK14_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA01G13520.1};	39.81	103	62	0	17	119	82	184	2e-19	91.7
rs:WP_013969826	phosphoribosyl-ATP diphosphatase [Treponema caldaria].	43.01	93	52	1	20	112	242	333	2e-19	92.4
rs:WP_011201041	phosphoribosyl-AMP cyclohydrolase [[Mannheimia] succiniciproducens].	43.33	90	51	0	24	113	12	101	2e-19	90.5
rs:NP_001042729	Os01g0276500 [Oryza sativa Japonica Group].	40.20	102	61	0	17	118	82	183	2e-19	91.7
tr:A0A0D3EMC0_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OBART01G11090.1};	39.81	103	62	0	17	119	83	185	2e-19	91.7
rs:XP_009358242	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic-like isoform X1 [Pyrus x bretschneideri].	39.05	105	64	0	17	121	64	168	2e-19	91.3
rs:WP_013867131	phosphoribosyl-AMP cyclohydrolase [Methanothermococcus okinawensis].	45.45	99	53	1	25	123	22	119	2e-19	88.6
tr:A0A0E0C0N9_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OMERI01G11060.1};	40.20	102	61	0	17	118	82	183	2e-19	91.3
rs:WP_045811875	imidazole glycerol phosphate synthase [Brevundimonas sp. KM4].	38.94	113	68	1	13	124	2	114	2e-19	90.1
rs:XP_011005510	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic [Populus euphratica].	36.36	110	70	0	17	126	64	173	2e-19	91.3
rs:WP_036008569	phosphoribosyl-AMP cyclohydrolase, partial [Leptolyngbya sp. JSC-1].	62.90	62	23	0	18	79	4	65	2e-19	86.7
rs:WP_010248071	phosphoribosyl-AMP cyclohydrolase [Pantoea sp. SL1_M5].	41.05	95	56	0	24	118	17	111	3e-19	90.1
rs:WP_027377395	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium palustre].	39.45	109	57	1	24	123	10	118	3e-19	89.7
tr:A0A067EQT3_CITSI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDO53567.1}; Flags: Fragment;	37.86	103	64	0	17	119	7	109	3e-19	88.6
tr:A0A0D9UZM1_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:LPERR01G10470.1};	39.45	109	66	0	17	125	93	201	3e-19	94.4
rs:XP_006415287	hypothetical protein EUTSA_v10008417mg [Eutrema salsugineum].	38.61	101	62	0	18	118	59	159	3e-19	90.9
rs:XP_012437197	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic-like isoform X1 [Gossypium raimondii].	36.27	102	65	0	17	118	63	164	3e-19	89.4
rs:WP_031237369	imidazole glycerol phosphate synthase [Asticcacaulis sp. AC460].	43.00	100	56	1	14	112	15	114	3e-19	90.1
sp:HIS3_METM5	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	44.09	93	51	1	25	117	24	115	3e-19	88.2
tr:V4R7S0_9CAUL	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	43.00	100	56	1	14	112	21	120	3e-19	90.1
rs:WP_032483784	phosphoribosyl-ATP pyrophosphatase, partial [Yersinia pestis].	49.35	77	39	0	25	101	18	94	3e-19	87.0
rs:WP_007846523	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Chryseobacterium].	41.67	96	55	1	18	112	2	97	3e-19	89.7
sp:HIS3_METM7	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	38.71	124	66	3	11	125	1	123	3e-19	88.2
tr:K2C0E1_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	43.82	89	50	0	24	112	2	90	3e-19	89.4
tr:A0A067ERN6_CITSI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDO53566.1}; Flags: Fragment;	37.86	103	64	0	17	119	7	109	3e-19	89.0
rs:WP_035324645	phosphoribosyl-ATP pyrophosphatase [Dokdonia donghaensis].	41.58	101	54	1	11	111	3	98	4e-19	89.4
rs:XP_006645764	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic-like, partial [Oryza brachyantha].	38.83	103	63	0	17	119	13	115	4e-19	90.1
rs:WP_012800793	phosphoribosyl-ATP diphosphatase [Kangiella koreensis].	45.36	97	53	0	16	112	222	318	4e-19	91.7
rs:XP_004302491	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic-like [Fragaria vesca subsp. vesca].	39.22	102	62	0	17	118	62	163	4e-19	90.5
rs:XP_009404731	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic [Musa acuminata subsp. malaccensis].	38.24	102	63	0	17	118	62	163	4e-19	90.5
rs:WP_000098497	phosphoribosyl-AMP cyclohydrolase [Leptospira interrogans].	41.51	106	59	2	10	113	60	164	4e-19	89.0
rs:WP_042506231	phosphoribosyl-ATP pyrophosphatase, partial [Xanthomonas vasicola].	50.67	75	37	0	38	112	1	75	5e-19	88.6
tr:X1T5S0_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_S08178 {ECO:0000313|EMBL:GAJ00678.1}; Flags: Fragment;	52.78	72	33	1	43	113	1	72	5e-19	86.7
tr:K2B7U5_9BACT	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	43.82	89	50	0	24	112	6	94	5e-19	89.0
rs:WP_027385357	phosphoribosyl-ATP pyrophosphatase [Chryseobacterium gregarium].	40.20	102	55	1	11	112	3	98	5e-19	89.0
tr:H2CJX3_9LEPT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	38.14	118	63	4	11	119	34	150	5e-19	88.2
rs:WP_021778865	phosphoribosyl-AMP cyclohydrolase [Dokdonia sp. MED134].	41.58	101	54	1	11	111	3	98	5e-19	89.0
sp:HIS3_LEPIN	RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19;	41.51	106	59	2	10	113	60	164	5e-19	88.6
rs:NP_001150567	histidine biosynthesis bifunctional protein hisIE [Zea mays].	38.83	103	63	0	17	119	75	177	6e-19	90.1
rs:WP_043145512	phosphoribosyl-AMP cyclohydrolase [Sphingobium xenophagum].	40.95	105	61	1	14	117	15	119	6e-19	87.8
tr:K7V902_MAIZE	SubName: Full=Histidine biosynthesis protein hisIE {ECO:0000313|EMBL:AFW79537.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:GRMZM2G082214_P01};	38.83	103	63	0	17	119	75	177	6e-19	90.1
tr:C3HFX1_BACTU	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	52.86	70	33	0	44	113	1	70	6e-19	85.9
tr:K2F1A4_9BACT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	40.86	93	54	1	23	114	2	94	6e-19	86.7
rs:WP_002167964	phosphoribosyl-AMP cyclohydrolase, partial [Leptospira interrogans].	41.51	106	59	2	10	113	60	164	6e-19	88.2
tr:A0A0B0NJ40_GOSAR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KHG12835.1};	35.45	110	71	0	9	118	55	164	6e-19	89.7
rs:WP_010260587	phosphoribosyl-ATP diphosphatase [Treponema primitia].	43.62	94	52	1	21	114	265	357	7e-19	91.3
sp:HIS3_METVA	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	42.45	106	60	1	12	117	18	122	7e-19	87.4
rs:XP_012467546	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic-like isoform X1 [Gossypium raimondii].	35.45	110	71	0	9	118	55	164	7e-19	89.7
rs:XP_010929493	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic isoform X2 [Elaeis guineensis].	38.61	101	62	0	18	118	72	172	7e-19	89.4
rs:WP_026849082	phosphoribosyl-AMP cyclohydrolase [Gemmatimonas sp. AP64].	46.53	101	52	2	13	112	5	104	7e-19	88.6
rs:WP_042767208	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase, partial [Streptococcus].	56.72	67	29	0	52	118	5	71	8e-19	85.5
rs:XP_002457646	hypothetical protein SORBIDRAFT_03g011110 [Sorghum bicolor].	38.60	114	66	1	10	119	62	175	8e-19	89.7
rs:XP_008224526	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic [Prunus mume].	39.05	105	64	0	17	121	64	168	8e-19	89.7
rs:WP_009662459	nickel transporter [Lachnoanaerobaculum sp. ICM7].	38.32	107	66	0	12	118	14	120	8e-19	86.7
tr:A0A067EI42_CITSI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDO53565.1}; Flags: Fragment;	37.86	103	64	0	17	119	7	109	8e-19	89.0
rs:XP_012467551	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic-like isoform X2 [Gossypium raimondii].	36.27	102	65	0	17	118	18	119	8e-19	89.4
rs:XP_007205670	hypothetical protein PRUPE_ppa009521mg [Prunus persica].	39.05	105	64	0	17	121	64	168	8e-19	89.7
tr:K3XKH4_SETIT	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Si002397m};	40.00	100	60	0	17	116	75	174	9e-19	89.7
rs:WP_020775261	phosphoribosyl-AMP cyclohydrolase [Leptospira alstonii].	46.07	89	47	1	25	113	77	164	9e-19	88.2
rs:XP_010678489	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic [Beta vulgaris subsp. vulgaris].	36.19	105	67	0	17	121	63	167	9e-19	89.4
sp:HIS3_METM6	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	43.01	93	52	1	25	117	24	115	1e-18	86.7
tr:F2DSJ4_HORVD	SubName: Full=Predicted protein {ECO:0000313|EMBL:BAJ98065.1};	38.83	103	63	0	17	119	74	176	1e-18	88.6
rs:WP_044840986	phosphoribosyl-ATP pyrophosphatase [Thalassomonas viridans].	44.44	90	50	0	23	112	17	106	1e-18	88.6
rs:WP_004778451	phosphoribosyl-AMP cyclohydrolase [Leptospira kirschneri].	40.00	110	63	2	6	113	56	164	1e-18	88.2
rs:WP_000122095	phosphoribosyl-AMP cyclohydrolase [Leptospira interrogans].	41.51	106	59	2	10	113	60	164	1e-18	88.2
sp:HIS3_LEPIC	RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19;	41.51	106	59	2	10	113	60	164	1e-18	88.2
rs:WP_029563999	hypothetical protein, partial [alpha proteobacterium SCGC AAA240-E13].	48.00	75	39	0	19	93	20	94	1e-18	85.9
rs:XP_010929492	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic isoform X1 [Elaeis guineensis].	38.61	101	62	0	18	118	72	172	1e-18	89.4
rs:XP_006470873	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic-like [Citrus sinensis].	36.94	111	70	0	9	119	48	158	1e-18	89.4
rs:XP_011101321	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic [Sesamum indicum].	37.27	110	69	0	17	126	57	166	1e-18	89.4
rs:WP_004764665	phosphoribosyl-AMP cyclohydrolase [Leptospira kirschneri].	40.00	110	63	2	6	113	56	164	1e-18	87.8
tr:T1MBW3_TRIUA	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:TRIUR3_15114-P1}; Flags: Fragment;	38.83	103	63	0	17	119	39	141	1e-18	89.0
rs:XP_008797105	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic [Phoenix dactylifera].	38.24	102	63	0	17	118	71	172	1e-18	89.0
rs:XP_004309896	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic-like [Fragaria vesca subsp. vesca].	36.84	114	68	1	9	118	56	169	1e-18	89.0
tr:M8C8W1_AEGTA	SubName: Full=Histidine biosynthesis bifunctional protein hisIE, chloroplastic {ECO:0000313|EMBL:EMT23487.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:EMT23487};	38.83	103	63	0	17	119	74	176	1e-18	89.0
tr:F2DYY1_HORVD	SubName: Full=Predicted protein {ECO:0000313|EMBL:BAK00303.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:MLOC_21279.1};	38.83	103	63	0	17	119	74	176	1e-18	89.0
rs:WP_025474826	hypothetical protein, partial [Yersinia pestis].	50.68	73	36	0	25	97	18	90	1e-18	85.5
rs:WP_028685646	phosphoribosyl-ATP pyrophosphatase [Phaseolibacter flectens].	42.70	89	51	0	24	112	17	105	1e-18	87.8
rs:XP_006420707	hypothetical protein CICLE_v10005565mg [Citrus clementina].	36.89	103	65	0	17	119	56	158	1e-18	87.8
rs:XP_010538347	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic-like [Tarenaya hassleriana].	38.61	101	62	0	18	118	59	159	1e-18	89.0
rs:WP_023388570	phosphoribosyl-AMP cyclohydrolase [Youngiibacter fragilis].	43.56	101	54	2	14	112	3	102	2e-18	87.8
tr:A0A077RF25_WHEAT	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:TRAES3BF181300030CFD_t1}; SubName: Full=WGS project CBUC00000000 data, cultivar Chinese Spring, contig v443_1813 {ECO:0000313|EMBL:CDJ26587.1};	38.83	103	63	0	17	119	74	176	2e-18	89.0
sp:HIS2_BUCBP	RecName: Full=Histidine biosynthesis bifunctional protein HisIE; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase; Short=PRA-PH; EC=3.6.1.31;	39.33	89	54	0	24	112	17	105	2e-18	87.8
rs:WP_015465299	phosphoribosyl-AMP cyclohydrolase [Psychromonas sp. CNPT3].	42.05	88	51	0	25	112	22	109	2e-18	87.8
rs:WP_041398244	phosphoribosyl-AMP cyclohydrolase [Spirochaeta africana].	37.61	117	64	3	18	125	10	126	2e-18	85.9
rs:WP_041881310	hypothetical protein [Candidatus Altimarinus pacificus].	40.66	91	54	0	24	114	11	101	2e-18	87.4
rs:WP_020034577	hypothetical protein, partial [Oceanospirillales bacterium SCGC AAA298-N10].	47.37	76	40	0	21	96	9	84	2e-18	84.7
rs:XP_007032053	Histidine biosynthesis bifunctional protein [Theobroma cacao].	35.45	110	71	0	9	118	55	164	2e-18	89.0
rs:WP_021331236	phosphoribosyl-ATP diphosphatase [Treponema socranskii].	42.31	104	59	1	9	112	235	337	2e-18	89.7
tr:H9ULV7_SPIAZ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	37.61	117	64	3	18	125	28	144	2e-18	86.3
rs:XP_003567089	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic [Brachypodium distachyon].	38.83	103	63	0	17	119	73	175	2e-18	88.6
rs:WP_025474078	hypothetical protein, partial [Yersinia pestis].	50.70	71	35	0	25	95	18	88	2e-18	84.7
rs:WP_025475588	hypothetical protein, partial [Yersinia pestis].	50.70	71	35	0	25	95	18	88	3e-18	84.7
rs:XP_006852623	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic [Amborella trichopoda].	39.18	97	59	0	18	114	62	158	3e-18	88.2
rs:XP_002277244	PREDICTED: histidine biosynthesis bifunctional protein hisIE, chloroplastic [Vitis vinifera].	38.24	102	63	0	17	118	63	164	3e-18	88.2
rs:XP_006420706	hypothetical protein CICLE_v10005565mg [Citrus clementina].	36.04	111	71	0	9	119	48	158	3e-18	87.8
rs:WP_008607629	phosphoribosyl-AMP cyclohydrolase [Alishewanella aestuarii].	44.90	98	54	0	16	113	7	104	3e-18	87.0
rs:XP_006420709	hypothetical protein CICLE_v10005565mg [Citrus clementina].	36.04	111	71	0	9	119	57	167	3e-18	87.8
tr:A0A0A9UAS2_ARUDO	SubName: Full=Histidine biosynthesis bifunctional protein hisIE {ECO:0000313|EMBL:JAF80553.1};	38.05	113	66	1	10	118	64	176	3e-18	88.2
rs:WP_002180232	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Leptospira].	40.00	110	63	2	6	113	56	164	3e-18	86.7
rs:WP_040919296	phosphoribosyl-AMP cyclohydrolase [Leptonema illini].	39.22	102	55	2	25	119	10	111	3e-18	85.1
rs:WP_012840962	phosphoribosyl-AMP cyclohydrolase [Blattabacterium sp. (Blattella germanica)].	40.23	87	52	0	25	111	17	103	3e-18	87.0
rs:WP_002638518	phosphoribosyl-AMP cyclohydrolase [Myxococcus sp. (contaminant ex DSM 436)].	43.69	103	51	2	10	112	6	101	4e-18	86.7
rs:WP_013877800	phosphoribosyl-AMP cyclohydrolase [Buchnera aphidicola].	37.50	88	55	0	25	112	18	105	4e-18	86.7
rs:WP_002147930	phosphoribosyl-AMP cyclohydrolase [Leptospira noguchii].	40.00	110	63	2	6	113	56	164	4e-18	86.3
sp:HIS3_SULSO	RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19;	47.30	74	39	0	40	113	1	74	4e-18	84.0
rs:WP_004456154	phosphoribosyl-AMP cyclohydrolase [Leptospira noguchii].	40.00	110	63	2	6	113	56	164	4e-18	86.3
rs:WP_044820570	hypothetical protein, partial [Bacteroides fragilis].	43.00	100	49	3	11	108	3	96	5e-18	84.0
rs:WP_004433710	phosphoribosyl-AMP cyclohydrolase [Leptospira noguchii].	40.00	110	63	2	6	113	56	164	5e-18	86.3
tr:A0A0D2TZQ7_GOSRA	SubName: Full=Gossypium raimondii chromosome 8, whole genome shotgun sequence {ECO:0000313|EMBL:KJB48810.1};	36.00	100	64	0	17	116	63	162	5e-18	87.0
rs:WP_024037318	hypothetical protein, partial [Intestinibacter bartlettii].	52.86	70	33	0	47	116	2	71	5e-18	83.6
tr:N1UNC0_LEPIR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	43.82	89	49	1	25	113	1	88	5e-18	84.3
tr:F3FKD9_PSESX	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:EGH30675.1}; EC=3.5.4.19 {ECO:0000313|EMBL:EGH30675.1}; Flags: Fragment;	52.00	75	35	1	57	130	2	76	5e-18	83.6
rs:WP_041077445	hypothetical protein [Thermotoga caldifontis].	44.68	94	50	1	25	116	2	95	6e-18	86.3
rs:WP_034214545	nickel transporter [Lachnoanaerobaculum sp. MSX33].	36.45	107	68	0	12	118	14	120	6e-18	84.3
rs:WP_007591231	nickel transporter [Lachnoanaerobaculum sp. OBRC5-5].	36.45	107	68	0	12	118	14	120	6e-18	84.3
tr:F8IAI2_SULAT	RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000256|HAMAP-Rule:MF_01020}; Short=PRA-PH {ECO:0000256|HAMAP-Rule:MF_01020}; EC=3.6.1.31 {ECO:0000256|HAMAP-Rule:MF_01020};	44.44	90	50	0	35	124	3	92	6e-18	85.9
rs:WP_015581253	phosphoribosyl-AMP cyclohydrolase [Sulfolobus islandicus].	47.14	70	37	0	44	113	1	70	7e-18	83.2
rs:WP_008951515	phosphoribosyl-AMP cyclohydrolase [Alishewanella jeotgali].	44.79	96	53	0	18	113	9	104	7e-18	85.9
rs:WP_042106063	phosphoribosyl-ATP pyrophosphatase [Escherichia coli].	43.82	89	43	1	24	112	17	98	8e-18	85.9
rs:WP_022478837	phosphoribosyl-AMP cyclohydrolase [Coraliomargarita sp. CAG:312].	35.07	134	77	3	1	124	1	134	8e-18	84.7
rs:WP_009446293	nickel transporter [Lachnospiraceae bacterium oral taxon 082].	37.38	107	67	0	12	118	14	120	9e-18	84.0
rs:WP_017445256	hypothetical protein [Gayadomonas joobiniege].	40.45	89	53	0	24	112	18	106	9e-18	85.9
sp:HIS3_META3	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01021}; Short=PRA-CH {ECO:0000255|HAMAP-Rule:MF_01021}; EC=3.5.4.19 {ECO:0000255|HAMAP-Rule:MF_01021};	47.67	86	42	1	28	113	27	109	1e-17	84.0
tr:D0HFV7_VIBMI	RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000256|HAMAP-Rule:MF_01020}; Short=PRA-PH {ECO:0000256|HAMAP-Rule:MF_01020}; EC=3.6.1.31 {ECO:0000256|HAMAP-Rule:MF_01020};	52.17	69	33	0	44	112	1	69	1e-17	84.7
rs:WP_009220857	nickel transporter [Lachnospiraceae oral taxon 107].	33.64	107	71	0	12	118	14	120	1e-17	83.6
rs:WP_018123004	hypothetical protein [Wohlfahrtiimonas chitiniclastica].	44.44	90	50	0	23	112	264	353	1e-17	87.8
rs:WP_033330772	hypothetical protein [Actinomadura madurae].	42.72	103	52	2	23	118	9	111	1e-17	83.6
rs:WP_016550254	phosphoribosyl-AMP cyclohydrolase [Leptospira fainei].	42.00	100	56	2	14	113	64	161	1e-17	84.7
rs:WP_003006571	phosphoribosyl-AMP cyclohydrolase [Leptospira weilii].	44.94	89	48	1	25	113	77	164	1e-17	85.1
tr:Q1NG03_SPHSS	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	38.60	114	62	2	19	131	22	128	2e-17	84.3
rs:WP_008984113	phosphoribosyl-AMP cyclohydrolase [Alishewanella agri].	44.79	96	53	0	18	113	9	104	2e-17	85.1
rs:WP_002630837	phosphoribosyl-AMP cyclohydrolase [Leptospira weilii].	38.26	115	68	2	9	121	59	172	2e-17	84.7
sp:HIS3_METMP	RecName: Full=Phosphoribosyl-AMP cyclohydrolase; Short=PRA-CH; EC=3.5.4.19;	36.21	116	73	1	2	117	1	115	2e-17	83.6
rs:WP_037542096	phosphoribosyl-AMP cyclohydrolase [Sphingomonas sp. SKA58].	38.60	114	62	2	19	131	20	126	2e-17	84.0
rs:WP_020781491	phosphoribosyl-AMP cyclohydrolase [Leptospira sp. P2653].	41.35	104	60	1	18	121	70	172	2e-17	84.7
rs:WP_016758522	phosphoribosyl-AMP cyclohydrolase [Leptospira weilii].	41.35	104	60	1	18	121	70	172	2e-17	84.7
rs:WP_004499271	phosphoribosyl-AMP cyclohydrolase [Leptospira weilii].	41.35	104	60	1	18	121	70	172	2e-17	84.7
rs:WP_008314065	hypothetical protein [Wohlfahrtiimonas chitiniclastica].	44.44	90	50	0	23	112	264	353	2e-17	87.4
rs:XP_004971545	PREDICTED: uncharacterized protein LOC101758684 [Setaria italica].	40.00	100	60	0	17	116	878	977	2e-17	89.0
rs:XP_002949193	hypothetical protein VOLCADRAFT_59102 [Volvox carteri f. nagariensis].	42.55	94	54	0	17	110	7	100	2e-17	85.1
rs:WP_015681510	phosphoribosyl-AMP cyclohydrolase [Leptospira wolbachii].	36.13	119	65	2	5	113	64	181	2e-17	84.7
rs:WP_002752403	phosphoribosyl-AMP cyclohydrolase [Leptospira borgpetersenii].	42.27	97	55	1	25	121	77	172	3e-17	84.0
rs:WP_011670808	phosphoribosyl-AMP cyclohydrolase [Leptospira borgpetersenii].	42.27	97	55	1	25	121	77	172	3e-17	84.0
rs:WP_002746726	phosphoribosyl-AMP cyclohydrolase [Leptospira borgpetersenii].	40.57	106	62	1	25	130	77	181	3e-17	84.0
rs:WP_004506601	phosphoribosyl-AMP cyclohydrolase [Leptospira weilii].	42.27	97	55	1	25	121	77	172	4e-17	84.0
rs:WP_027472530	phosphoribosyl-ATP pyrophosphatase [Saccharicrinis fermentans].	46.07	89	48	0	24	112	11	99	4e-17	84.0
rs:WP_010576699	phosphoribosyl-AMP cyclohydrolase [Leptospira alexanderi].	42.27	97	55	1	25	121	77	172	4e-17	84.0
rs:WP_015677368	phosphoribosyl-AMP cyclohydrolase [Leptospira yanagawae].	44.83	87	47	1	27	113	96	181	4e-17	84.0
tr:K1RJE0_9ZZZZ	SubName: Full=Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein {ECO:0000313|EMBL:EKC43744.1}; Flags: Fragment;	44.44	72	40	0	40	111	1	72	5e-17	83.2
rs:XP_008355177	PREDICTED: LOW QUALITY PROTEIN: histidine biosynthesis bifunctional protein hisIE, chloroplastic-like [Malus domestica].	37.14	105	66	0	17	121	16	120	5e-17	84.3
rs:WP_015707060	phosphoribosyl-ATP diphosphatase [Treponema primitia].	44.94	89	48	1	26	114	262	349	7e-17	85.9
rs:WP_004452436	phosphoribosyl-AMP cyclohydrolase [Leptospira noguchii].	41.07	112	59	4	6	113	56	164	7e-17	83.2
tr:X1L6L1_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S20085 {ECO:0000313|EMBL:GAH89808.1}; Flags: Fragment;	60.00	60	24	0	17	76	6	65	9e-17	80.1
rs:WP_019791815	hypothetical protein, partial [Streptococcus sobrinus].	57.38	61	26	0	54	114	1	61	9e-17	79.7
rs:WP_012390226	phosphoribosyl-AMP cyclohydrolase [Leptospira biflexa].	42.70	89	50	1	25	113	94	181	1e-16	82.8
rs:WP_002733987	phosphoribosyl-AMP cyclohydrolase [Leptospira borgpetersenii].	41.24	97	56	1	25	121	77	172	1e-16	82.4
tr:A0A0B8P0B9_9VIBR	RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000256|HAMAP-Rule:MF_01020}; Short=PRA-PH {ECO:0000256|HAMAP-Rule:MF_01020}; EC=3.6.1.31 {ECO:0000256|HAMAP-Rule:MF_01020};	50.72	69	34	0	44	112	1	69	1e-16	82.0
tr:A0A0E1MXG4_BACAN	SubName: Full=Phosphoribosyl-AMP cyclohydrolase family protein {ECO:0000313|EMBL:AJH89211.1};	53.03	66	31	0	24	89	8	73	1e-16	79.7
rs:WP_016546103	phosphoribosyl-AMP cyclohydrolase [Leptospira wolffii].	41.82	110	62	2	18	127	68	175	1e-16	82.0
rs:WP_026714186	phosphoribosyl-AMP cyclohydrolase [Flavobacterium daejeonense].	36.11	108	61	3	14	113	10	117	1e-16	80.9
rs:WP_014805063	phosphoribosyl-AMP cyclohydrolase [Turneriella parva].	36.04	111	63	3	11	113	15	125	2e-16	80.9
rs:WP_002758491	phosphoribosyl-AMP cyclohydrolase [Leptospira borgpetersenii].	41.24	97	56	1	25	121	77	172	2e-16	82.0
tr:X0X1D4_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_S25767 {ECO:0000313|EMBL:GAG36825.1}; Flags: Fragment;	47.76	67	35	0	53	119	1	67	2e-16	79.7
rs:WP_002729506	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Leptospira].	41.24	97	56	1	25	121	77	172	2e-16	82.0
rs:WP_015712327	phosphoribosyl-ATP diphosphatase [Treponema azotonutricium].	42.22	90	51	1	25	114	261	349	2e-16	84.3
tr:B7R806_9THEO	RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000256|HAMAP-Rule:MF_01020}; Short=PRA-PH {ECO:0000256|HAMAP-Rule:MF_01020}; EC=3.6.1.31 {ECO:0000256|HAMAP-Rule:MF_01020};	46.34	82	40	1	44	121	1	82	2e-16	81.3
tr:A0A090PSE1_9FLAO	RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000256|HAMAP-Rule:MF_01020}; Short=PRA-PH {ECO:0000256|HAMAP-Rule:MF_01020}; EC=3.6.1.31 {ECO:0000256|HAMAP-Rule:MF_01020};	46.15	78	38	1	44	121	1	74	3e-16	81.3
rs:WP_004476081	phosphoribosyl-AMP cyclohydrolase [Leptospira santarosai].	39.32	117	64	3	9	121	59	172	3e-16	81.3
rs:WP_004466354	phosphoribosyl-AMP cyclohydrolase [Leptospira santarosai].	39.32	117	64	3	9	121	59	172	3e-16	81.3
rs:WP_004484875	phosphoribosyl-AMP cyclohydrolase [Leptospira santarosai].	39.32	117	64	3	9	121	59	172	3e-16	81.3
rs:WP_004471657	phosphoribosyl-AMP cyclohydrolase [Leptospira santarosai].	39.32	117	64	3	9	121	59	172	3e-16	81.3
tr:T0V3K3_9STRE	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	57.63	59	25	0	60	118	3	61	3e-16	78.6
rs:WP_026964422	phosphoribosyl-AMP cyclohydrolase [Alicyclobacillus pomorum].	40.00	100	59	1	15	113	10	109	3e-16	79.7
rs:WP_004486459	phosphoribosyl-AMP cyclohydrolase [Leptospira santarosai].	39.32	117	61	2	14	121	57	172	3e-16	81.3
rs:WP_046417984	phosphoribosyl-ATP pyrophosphatase, partial [Bacteroides sp. UNK.MGS-13].	46.58	73	39	0	23	95	9	81	4e-16	79.0
rs:WP_045118051	hypothetical protein [Candidatus Tremblaya phenacola].	42.11	95	52	1	28	119	31	125	4e-16	81.6
tr:R9YJT8_9PROT	SubName: Full=Bifunctional phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphatase {ECO:0000313|EMBL:AGO28319.1};	42.11	95	52	1	28	119	20	114	4e-16	81.6
rs:WP_004494687	phosphoribosyl-AMP cyclohydrolase [Leptospira santarosai].	39.32	117	61	2	14	121	57	172	4e-16	80.9
tr:U4S8D9_HAEPR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	43.24	74	42	0	40	113	1	74	4e-16	79.3
rs:WP_004477965	phosphoribosyl-AMP cyclohydrolase [Leptospira santarosai].	39.32	117	64	3	9	121	59	172	4e-16	80.9
rs:WP_027135515	hypothetical protein [Geminicoccus roseus].	45.56	90	47	2	24	112	230	318	5e-16	83.2
rs:WP_004459518	phosphoribosyl-AMP cyclohydrolase [Leptospira santarosai].	39.32	117	64	3	9	121	59	172	5e-16	80.9
rs:WP_004480725	MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Leptospira].	39.32	117	64	3	9	121	59	172	6e-16	80.5
tr:W8PJD5_9RHIZ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	44.57	92	49	1	25	114	5	96	6e-16	78.6
rs:WP_016755553	phosphoribosyl-AMP cyclohydrolase [Leptospira santarosai].	39.32	117	64	3	9	121	59	172	6e-16	80.5
tr:A0A085ELV3_9FLAO	RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000256|HAMAP-Rule:MF_01020}; Short=PRA-PH {ECO:0000256|HAMAP-Rule:MF_01020}; EC=3.6.1.31 {ECO:0000256|HAMAP-Rule:MF_01020};	44.44	72	40	0	40	111	1	72	6e-16	80.1
rs:WP_035050955	phosphoribosyl-ATP pyrophosphatase [Carnobacterium pleistocenium].	40.45	89	53	0	24	112	14	102	6e-16	80.9
rs:WP_020783912	phosphoribosyl-AMP cyclohydrolase [Leptospira santarosai].	39.32	117	64	3	9	121	59	172	6e-16	80.5
rs:XP_008363500	PREDICTED: LOW QUALITY PROTEIN: histidine biosynthesis bifunctional protein hisIE, chloroplastic-like [Malus domestica].	37.14	105	66	0	17	121	64	168	7e-16	80.9
tr:M6VKU9_9LEPT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	39.32	117	64	3	9	121	59	172	7e-16	80.5
rs:WP_046689748	phosphoribosyl-AMP cyclohydrolase [Leptospira santarosai].	39.32	117	64	3	9	121	59	172	8e-16	80.1
rs:WP_004474336	phosphoribosyl-AMP cyclohydrolase [Leptospira santarosai].	39.32	117	64	3	9	121	59	172	8e-16	80.1
tr:A0A0B8QB58_9VIBR	RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000256|HAMAP-Rule:MF_01020}; Short=PRA-PH {ECO:0000256|HAMAP-Rule:MF_01020}; EC=3.6.1.31 {ECO:0000256|HAMAP-Rule:MF_01020};	49.28	69	35	0	44	112	1	69	8e-16	79.7
rs:WP_034546825	phosphoribosyl-ATP pyrophosphatase [Carnobacterium alterfunditum].	40.45	89	53	0	24	112	14	102	9e-16	80.5
tr:U4S5S9_HAEPR	RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000256|HAMAP-Rule:MF_01020}; Short=PRA-PH {ECO:0000256|HAMAP-Rule:MF_01020}; EC=3.6.1.31 {ECO:0000256|HAMAP-Rule:MF_01020};	43.24	74	42	0	40	113	1	74	9e-16	80.1
rs:WP_004468286	phosphoribosyl-AMP cyclohydrolase [Leptospira santarosai].	42.27	97	55	1	25	121	77	172	9e-16	80.1
rs:WP_002976022	phosphoribosyl-AMP cyclohydrolase [Leptospira vanthielii].	41.57	89	51	1	25	113	94	181	9e-16	80.1
rs:WP_020776242	phosphoribosyl-AMP cyclohydrolase [Leptospira meyeri].	39.56	91	54	1	23	113	92	181	1e-15	80.1
rs:WP_018154269	hypothetical protein [Methanothermococcus thermolithotrophicus].	44.94	89	48	1	25	113	25	112	1e-15	78.6
tr:A0A090WQN3_9FLAO	RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000256|HAMAP-Rule:MF_01020}; Short=PRA-PH {ECO:0000256|HAMAP-Rule:MF_01020}; EC=3.6.1.31 {ECO:0000256|HAMAP-Rule:MF_01020};	41.18	85	40	1	44	118	1	85	1e-15	79.3
rs:WP_004489211	phosphoribosyl-AMP cyclohydrolase [Leptospira santarosai].	42.27	97	55	1	25	121	77	172	1e-15	79.7
rs:WP_004787320	phosphoribosyl-AMP cyclohydrolase [Leptospira meyeri].	39.56	91	54	1	23	113	92	181	2e-15	79.7
rs:WP_008751029	nickel transporter [Lachnoanaerobaculum saburreum].	36.45	107	66	1	12	118	14	118	2e-15	77.8
tr:A0A060KXW3_9RHIZ	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	43.48	92	50	1	25	114	5	96	2e-15	77.4
tr:X1HDL6_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_L02203 {ECO:0000313|EMBL:GAH43403.1};	45.95	74	40	0	40	113	1	74	2e-15	77.0
rs:WP_034669338	phosphoribosyl-AMP cyclohydrolase, partial [Bacillus methanolicus].	39.22	102	58	1	11	112	1	98	2e-15	77.0
rs:WP_046421131	phosphoribosyl-ATP pyrophosphatase, partial [Bacteroides sp. UNK.MGS-13].	45.21	73	40	0	23	95	9	81	2e-15	76.6
rs:WP_008755065	nickel transporter [Lachnoanaerobaculum saburreum].	36.45	107	66	1	12	118	14	118	3e-15	77.4
rs:WP_034550520	phosphoribosyl-ATP pyrophosphatase [Carnobacterium funditum].	39.33	89	54	0	24	112	14	102	3e-15	79.0
rs:WP_028962816	hypothetical protein [Sulfobacillus thermosulfidooxidans].	44.21	95	51	1	20	112	4	98	3e-15	79.0
rs:WP_016278841	hypothetical protein [Lachnospiraceae bacterium A4].	35.71	112	65	3	25	131	25	134	3e-15	77.8
tr:I3E8V7_BACMT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	38.10	105	61	1	8	112	8	108	3e-15	77.0
rs:WP_041069549	phosphoribosyl-ATP pyrophosphatase [Candidatus Ishikawaella capsulata].	39.33	89	54	0	24	112	17	105	6e-15	78.2
rs:WP_020769827	phosphoribosyl-AMP cyclohydrolase [Leptospira sp. B5-022].	42.71	96	53	2	18	113	68	161	6e-15	77.8
rs:WP_002972379	phosphoribosyl-AMP cyclohydrolase [Leptospira terpstrae].	40.45	89	52	1	25	113	94	181	6e-15	78.2
tr:Q3A138_PELCD	RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000256|HAMAP-Rule:MF_01020}; Short=PRA-PH {ECO:0000256|HAMAP-Rule:MF_01020}; EC=3.6.1.31 {ECO:0000256|HAMAP-Rule:MF_01020};	39.81	103	55	3	14	116	3	98	6e-15	78.2
rs:WP_034645571	phosphoribosyl-AMP cyclohydrolase, partial [Bacillus methanolicus].	39.22	102	58	1	11	112	1	98	8e-15	75.5
tr:I3DVI9_BACMT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	38.46	104	60	1	9	112	9	108	8e-15	76.3
tr:W4UE98_PROAA	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:GAE79291.1};	64.00	50	18	0	26	75	1	50	9e-15	74.3
rs:WP_039705920	phosphoribosyl-AMP cyclohydrolase [marine actinobacterium MedAcidi-G3].	35.00	120	68	4	7	116	9	128	1e-14	76.3
tr:M3H121_LEPIR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	45.95	74	40	0	40	113	1	74	2e-14	74.7
tr:X1IH31_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S21737 {ECO:0000313|EMBL:GAH81731.1};	41.89	74	43	0	40	113	1	74	2e-14	74.3
rs:WP_020383338	hypothetical protein, partial [Candidatus Poribacteria sp. WGA-4E].	60.38	53	21	0	64	116	1	53	2e-14	73.6
tr:Q6UA38_9ENTR	RecName: Full=Histidine biosynthesis bifunctional protein HisIE {ECO:0000256|HAMAP-Rule:MF_01019};	37.08	89	56	0	24	112	17	105	3e-14	76.3
tr:M0ZZV0_SOLTU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:PGSC0003DMT400011616};	36.71	79	50	0	40	118	1	79	3e-14	74.3
tr:Q56UT1_ALYLE	SubName: Full=Phosphoribosyl-ATP pyrophosphohydrolase/phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:AAT74591.1}; Flags: Fragment;	40.26	77	46	0	42	118	1	77	4e-14	75.5
rs:WP_010589602	phosphoribosyl-ATP diphosphatase [Acinetobacter parvus].	56.36	55	23	1	60	113	2	56	4e-14	75.5
tr:A0A0A0KNC8_CUCSA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGN51140.1};	40.51	79	47	0	40	118	1	79	6e-14	75.1
rs:WP_014887252	phosphoribosyl-AMP cyclohydrolase [Candidatus Carsonella ruddii].	30.77	91	63	0	22	112	15	105	8e-14	73.2
rs:WP_016587956	phosphoribosyl-AMP cyclohydrolase, partial [Yersinia pestis].	43.06	72	41	0	47	118	2	73	8e-14	74.3
rs:XP_009035206	hypothetical protein AURANDRAFT_17468, partial [Aureococcus anophagefferens].	39.18	97	50	3	25	113	1	96	9e-14	73.2
tr:S8DQX3_9LAMI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPS65458.1}; Flags: Fragment;	41.33	75	44	0	17	91	8	82	9e-14	72.4
rs:WP_016610070	phosphoribosyl-AMP cyclohydrolase, partial [Yersinia pestis].	44.78	67	37	0	52	118	2	68	9e-14	72.8
rs:XP_006305505	hypothetical protein CARUB_v10009971mg [Capsella rubella].	37.97	79	49	0	40	118	1	79	1e-13	74.3
tr:M0ZZU5_SOLTU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:PGSC0003DMT400011611};	36.71	79	50	0	40	118	1	79	1e-13	74.3
tr:A0A0D2C6W4_9EURO	SubName: Full=Strain CBS 89968 unplaced genomic scaffold supercont1.2, whole genome shotgun sequence {ECO:0000313|EMBL:KIW19319.1};	35.94	128	58	5	8	112	182	308	1e-13	77.8
tr:A9PAQ7_POPTR	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:ABK93460.1};	35.63	87	56	0	40	126	1	87	1e-13	74.3
tr:A0A0A8J4M4_ECOLX	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:BAQ01196.1}; Flags: Fragment;	46.15	65	35	0	48	112	1	65	1e-13	73.6
rs:WP_020915820	phosphoribosyl-AMP cyclohydrolase [Candidatus Carsonella ruddii].	26.37	91	67	0	22	112	15	105	2e-13	72.0
tr:A0A059LSH7_9CHLO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDD77055.1}; Flags: Fragment;	43.24	74	42	0	40	113	1	74	2e-13	75.1
tr:X1CBZ0_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_L08093 {ECO:0000313|EMBL:GAG81796.1}; Flags: Fragment;	47.76	67	35	0	47	113	46	112	3e-13	72.4
rs:WP_017255783	phosphoribosyl-AMP cyclohydrolase, partial [Pseudomonas tolaasii].	55.17	58	26	0	18	75	8	65	3e-13	70.9
rs:WP_008590371	phosphoribosyl-AMP cyclohydrolase [Leptospira licerasiae].	39.58	96	56	2	18	113	68	161	3e-13	73.2
tr:G0HID9_TREPR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	38.04	92	57	0	25	116	18	109	3e-13	73.6
tr:A0A072U1C8_MEDTR	SubName: Full=Histidine biosynthesis hisIE protein {ECO:0000313|EMBL:KEH23504.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:KEH23504};	39.24	79	48	0	40	118	1	79	3e-13	73.2
rs:WP_004012261	phosphoribosyl-ATP diphosphatase, partial [Escherichia coli].	46.77	62	33	0	51	112	3	64	3e-13	72.8
tr:K3X3I1_PYTUL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblProtists:PYU1_T011780};	41.11	90	51	2	24	112	274	362	3e-13	75.5
rs:WP_042990765	phosphoribosyl-AMP cyclohydrolase, partial [Bifidobacterium adolescentis].	55.36	56	25	0	18	73	20	75	4e-13	70.9
tr:A5KSK8_9BACT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	42.11	76	43	1	38	112	47	122	4e-13	72.0
tr:C6UMY7_HODCD	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	40.22	92	53	1	25	114	7	98	4e-13	71.2
rs:XP_003068858	Histidine biosynthesis trifunctional protein , putative [Coccidioides posadasii C735 delta SOWgp].	40.40	99	56	3	15	112	198	294	5e-13	75.9
tr:E9CXY0_COCPS	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:EFW20807.1};	40.40	99	56	3	15	112	198	294	6e-13	75.9
rs:XP_001243869	histidinol dehydrogenase [Coccidioides immitis RS].	40.40	99	56	3	15	112	198	294	6e-13	75.9
rs:XP_007726022	histidinol dehydrogenase [Capronia coronata CBS 617.96].	44.87	78	41	2	36	112	233	309	7e-13	75.5
tr:X1NRF6_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S03445 {ECO:0000313|EMBL:GAI29385.1};	47.06	68	36	0	40	107	1	68	8e-13	69.7
tr:M2RPF3_CERS8	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EMD40761.1};	40.66	91	51	3	24	112	191	280	9e-13	75.1
tr:A0A059BQE3_EUCGR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KCW68323.1};	35.44	79	51	0	40	118	1	79	1e-12	71.6
tr:W5DJN1_WHEAT	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Traes_3DS_C2EC764BC.1};	37.50	80	50	0	40	119	1	80	1e-12	71.2
tr:W5CJG0_WHEAT	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Traes_3AS_31089CA19.2};	36.59	82	52	0	40	121	1	82	1e-12	70.9
tr:R9KSM5_9FIRM	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	37.23	94	54	2	25	113	25	118	1e-12	70.5
rs:XP_012208557	hypothetical protein SPRG_13327 [Saprolegnia parasitica CBS 223.65].	37.76	98	50	2	24	111	196	292	1e-12	73.6
tr:W2N7Z1_PHYPR	SubName: Full=Phosphoribosyl-ATP diphosphatase {ECO:0000313|EMBL:ETM44762.1};	38.20	89	53	2	24	111	256	343	1e-12	73.6
tr:W2GPL5_PHYPR	SubName: Full=Phosphoribosyl-ATP diphosphatase {ECO:0000313|EMBL:ETK84917.1};	38.20	89	53	2	24	111	256	343	1e-12	73.6
tr:D8LDR4_ECTSI	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:CBN78471.1};	42.39	92	49	2	24	112	274	364	1e-12	73.6
tr:Q0FX88_PELBH	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	47.83	69	36	0	19	87	9	77	1e-12	70.9
rs:XP_007602317	histidine biosynthesis trifunctional protein [Colletotrichum fioriniae PJ7].	41.57	89	50	2	24	112	206	292	1e-12	74.3
tr:J3KYS0_ORYBR	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OB01G21260.1};	37.50	80	50	0	40	119	1	80	1e-12	71.2
tr:W2Z622_PHYPR	SubName: Full=Phosphoribosyl-ATP diphosphatase {ECO:0000313|EMBL:ETP42812.1};	38.20	89	53	2	24	111	256	343	1e-12	73.6
rs:XP_001780154	predicted protein [Physcomitrella patens].	38.96	77	47	0	40	116	1	77	2e-12	71.2
rs:WP_014887061	phosphoribosyl-AMP cyclohydrolase [Candidatus Carsonella ruddii].	33.33	87	58	0	26	112	18	104	2e-12	69.7
rs:XP_008608401	hypothetical protein SDRG_04504 [Saprolegnia diclina VS20].	37.37	99	51	2	24	112	196	293	2e-12	73.2
rs:WP_035613622	hypothetical protein, partial [Lachnospiraceae bacterium COE1].	37.23	94	54	2	25	113	14	107	2e-12	69.7
tr:A0A0C2X1Q9_AMAMU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIL68052.1};	40.00	90	51	3	24	112	189	276	2e-12	74.3
tr:B4FTI8_MAIZE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ACF85431.1};	37.50	80	50	0	40	119	1	80	2e-12	70.9
tr:M4C543_HYAAE	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblProtists:HpaP814214};	39.33	89	52	2	24	111	252	339	2e-12	73.6
tr:T0ZJ70_9ZZZZ	SubName: Full=Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein {ECO:0000313|EMBL:EQD44482.1};	50.85	59	29	0	60	118	3	61	2e-12	70.5
rs:XP_001837231	HIS4 [Coprinopsis cinerea okayama7#130].	42.22	90	49	3	24	112	195	282	2e-12	73.9
tr:A0A0D1X1J4_9EURO	SubName: Full=Exophiala sideris strain CBS 121828 unplaced genomic scaffold supercont1.2, whole genome shotgun sequence {ECO:0000313|EMBL:KIV81361.1};	37.19	121	54	5	11	112	192	309	2e-12	73.9
tr:H1VKV1_COLHI	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:CCF40854.1};	42.70	89	49	2	24	112	206	292	2e-12	73.9
rs:WP_043645284	phosphoribosyl-AMP cyclohydrolase, partial [Caenispirillum salinarum].	51.52	66	30	1	56	119	1	66	2e-12	68.9
tr:A0A0D2LQ39_9AGAR	SubName: Full=Unplaced genomic scaffold scaffold_1, whole genome shotgun sequence {ECO:0000313|EMBL:KJA30207.1};	40.00	90	51	3	24	112	193	280	2e-12	73.9
rs:XP_007302389	histidine biosynthesis trifunctional-protein [Stereum hirsutum FP-91666 SS1].	40.66	91	51	3	24	112	196	285	3e-12	73.6
rs:XP_009531251	hypothetical protein PHYSODRAFT_351968 [Phytophthora sojae].	37.78	90	54	2	24	112	257	345	3e-12	72.8
tr:A0A0D2BS69_9EURO	SubName: Full=Strain CBS 118157 unplaced genomic scaffold supercont1.4, whole genome shotgun sequence {ECO:0000313|EMBL:KIW55336.1};	44.00	75	40	2	39	112	236	309	3e-12	73.6
tr:A0A068TVE8_COFCA	SubName: Full=Coffea canephora DH200=94 genomic scaffold, scaffold_4 {ECO:0000313|EMBL:CDP00032.1};	35.44	79	51	0	40	118	1	79	3e-12	70.5
rs:XP_008089493	histidinol dehydrogenase [Colletotrichum graminicola M1.001].	42.70	89	49	2	24	112	206	292	3e-12	73.6
tr:G7XJ05_ASPKW	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:GAA86700.1};	44.87	78	41	2	36	112	216	292	3e-12	73.6
rs:XP_008893446	phosphoribosyl-ATP diphosphatase [Phytophthora parasitica INRA-310].	37.78	90	54	2	24	112	256	344	3e-12	72.8
tr:H3GIA7_PHYRM	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblProtists:Phyra75777};	38.20	89	53	2	24	111	257	344	3e-12	72.8
tr:F0WLR4_9STRA	SubName: Full=Putative uncharacterized protein ALNC14_083790 {ECO:0000313|EMBL:CCA22236.1};	37.78	90	54	2	24	112	243	331	4e-12	72.4
tr:A0A059BQ50_EUCGR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KCW68322.1};	37.35	83	52	0	17	99	59	141	4e-12	70.5
tr:A0A0C3H3L2_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIM98034.1};	41.11	90	50	3	24	112	205	292	4e-12	73.2
rs:XP_007673902	hypothetical protein BAUCODRAFT_154476 [Baudoinia compniacensis UAMH 10762].	47.44	78	39	2	36	112	904	980	4e-12	73.6
rs:XP_009157315	histidinol dehydrogenase [Exophiala dermatitidis NIH/UT8656].	42.31	78	43	2	36	112	233	309	4e-12	73.2
tr:M6KLS0_LEPIR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	48.39	62	32	0	52	113	2	63	4e-12	68.2
rs:XP_001389663	histidine biosynthesis trifunctional protein [Aspergillus niger CBS 513.88].	44.87	78	41	2	36	112	216	292	4e-12	73.2
rs:XP_002479213	phosphoribosyl-AMP cyclohydrolase, putative [Talaromyces stipitatus ATCC 10500].	42.22	90	49	3	24	112	203	290	4e-12	73.2
tr:A0A067NZ19_PLEOS	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDQ29382.1};	41.11	90	50	3	24	112	192	279	5e-12	72.8
rs:WP_022143962	phosphoribosyl-ATP diphosphatase [Ruminococcus sp. CAG:563].	37.08	89	54	2	26	112	14	102	5e-12	68.9
tr:T1BZ45_9ZZZZ	SubName: Full=Phosphoribosyl-AMP cyclohydrolase domain protein {ECO:0000313|EMBL:EQD78536.1}; EC=3.5.4.19 {ECO:0000313|EMBL:EQD78536.1}; Flags: Fragment;	50.88	57	28	0	18	74	1	57	5e-12	67.0
tr:A0A072PLY8_9EURO	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:KEF56555.1};	34.88	129	59	5	8	112	182	309	5e-12	72.8
rs:XP_009543728	hypothetical protein HETIRDRAFT_472383 [Heterobasidion irregulare TC 32-1].	40.66	91	51	3	24	112	195	284	5e-12	72.8
rs:XP_007754706	histidinol dehydrogenase [Cladophialophora yegresii CBS 114405].	42.31	78	43	2	36	112	233	309	5e-12	72.8
rs:XP_002903303	histidine biosynthesis trifunctional protein, putative [Phytophthora infestans T30-4].	40.26	77	45	1	36	111	267	343	6e-12	72.0
tr:A0A081A3U8_PHYPR	SubName: Full=Phosphoribosyl-ATP diphosphatase {ECO:0000313|EMBL:ETO73559.1};	37.78	90	54	2	24	112	256	344	6e-12	72.0
tr:T0JT09_COLGC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EQB43593.1};	42.70	89	49	2	24	112	206	292	6e-12	72.8
tr:A0A0C3CQJ7_HEBCY	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIM46116.1};	41.11	90	50	3	24	112	192	279	6e-12	72.4
rs:XP_007279999	histidinol dehydrogenase [Colletotrichum gloeosporioides Nara gc5].	42.70	89	49	2	24	112	206	292	6e-12	72.4
tr:W4MD19_9DELT	RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000256|HAMAP-Rule:MF_01020}; Short=PRA-PH {ECO:0000256|HAMAP-Rule:MF_01020}; EC=3.6.1.31 {ECO:0000256|HAMAP-Rule:MF_01020};	36.27	102	63	1	11	112	1	100	6e-12	69.7
rs:XP_003037910	hypothetical protein SCHCODRAFT_71835 [Schizophyllum commune H4-8].	42.22	90	49	3	24	112	192	279	7e-12	72.4
tr:W4LUU2_9DELT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETX01476.1}; Flags: Fragment;	36.27	102	63	1	11	112	1	100	7e-12	68.2
tr:A0A066XQR6_COLSU	SubName: Full=Putative histidinol dehydrogenase {ECO:0000313|EMBL:KDN68335.1};	41.57	89	50	2	24	112	206	292	7e-12	72.4
tr:A0A0D2MD70_GOSRA	SubName: Full=Gossypium raimondii chromosome 2, whole genome shotgun sequence {ECO:0000313|EMBL:KJB15792.1};	34.18	79	52	0	40	118	1	79	8e-12	69.3
rs:WP_014886871	phosphoribosyl-AMP cyclohydrolase [Candidatus Carsonella ruddii].	31.40	86	59	0	27	112	19	104	8e-12	67.8
rs:XP_003332401	histidinol dehydrogenase [Puccinia graminis f. sp. tritici CRL 75-36-700-3].	39.77	88	49	2	28	112	235	321	8e-12	72.4
tr:A0A0D2CYS7_9EURO	SubName: Full=Capronia semiimmersa strain CBS 27337 unplaced genomic scaffold supercont1.2, whole genome shotgun sequence {ECO:0000313|EMBL:KIW70366.1};	39.13	92	53	3	22	112	221	310	9e-12	72.4
rs:XP_002287285	probable phosphoribosyl-amp cyclohydrolase [Thalassiosira pseudonana CCMP1335].	41.46	82	44	1	35	112	76	157	9e-12	69.7
tr:A0A067TMV6_9AGAR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDR83672.1};	40.00	90	51	3	24	112	191	278	9e-12	72.0
tr:T5AND7_OPHSC	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:EQL03941.1};	40.66	91	52	2	22	112	202	290	1e-11	72.0
tr:A0A0D3CDI6_BRAOL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Bo5g048330.1};	40.54	74	44	0	18	91	61	134	1e-11	69.3
tr:A0A0D2AL99_9EURO	SubName: Full=Strain CBS 72588 unplaced genomic scaffold supercont1.7, whole genome shotgun sequence {ECO:0000313|EMBL:KIW40791.1};	42.67	75	41	2	39	112	235	308	1e-11	72.0
tr:A0A094SC83_9ZZZZ	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGA15728.1}; Flags: Fragment;	57.69	52	22	0	68	119	1	52	1e-11	66.2
rs:XP_003841128	similar to histidine biosynthesis protein [Leptosphaeria maculans JN3].	42.22	90	49	3	24	112	207	294	1e-11	71.6
rs:XP_001210745	histidinol dehydrogenase [Aspergillus terreus NIH2624].	43.59	78	42	2	36	112	216	292	1e-11	71.6
tr:A0A0B1P4Z9_UNCNE	SubName: Full=Putative histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:KHJ31739.1};	41.30	92	51	3	22	112	201	290	1e-11	71.6
tr:A0A0D2H8A0_9EURO	SubName: Full=Unplaced genomic scaffold supercont1.28, whole genome shotgun sequence {ECO:0000313|EMBL:KIW87090.1};	34.11	129	60	5	8	112	182	309	1e-11	71.6
rs:XP_008082208	ALDH-like protein [Glarea lozoyensis ATCC 20868].	39.33	89	51	3	25	112	208	294	1e-11	71.6
rs:XP_007750886	histidinol dehydrogenase [Cladophialophora psammophila CBS 110553].	34.11	129	60	5	8	112	182	309	1e-11	71.6
tr:H4U3X3_ECOLX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHV48043.1};	47.76	67	33	1	1	65	4	70	1e-11	66.2
rs:XP_007381963	histidine biosynthesis trifunctional-protein [Punctularia strigosozonata HHB-11173 SS5].	40.66	91	51	3	24	112	191	280	2e-11	71.2
tr:S5SXY2_9PROT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	25.25	99	73	1	14	111	14	112	2e-11	67.0
rs:XP_007812538	histidine biosynthesis trifunctional protein [Metarhizium acridum CQMa 102].	40.43	94	54	2	22	115	202	293	2e-11	71.2
tr:A0A0C3EKP5_9HOMO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIM68784.1};	39.56	91	52	3	24	112	191	280	2e-11	71.2
tr:A8AF10_CITK8	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ABV12073.1};	47.76	67	33	1	1	65	10	76	2e-11	66.2
rs:XP_002146919	phosphoribosyl-AMP cyclohydrolase, putative [Talaromyces marneffei ATCC 18224].	41.11	90	50	3	24	112	167	254	2e-11	71.2
tr:A0A0D2CYA6_9EURO	SubName: Full=Strain CBS 83496 unplaced genomic scaffold supercont1.1, whole genome shotgun sequence {ECO:0000313|EMBL:KIW34910.1};	41.03	78	44	2	36	112	233	309	2e-11	71.2
tr:A0A0D2HK97_9EURO	SubName: Full=Unplaced genomic scaffold supercont1.3, whole genome shotgun sequence {ECO:0000313|EMBL:KIY02311.1};	41.03	78	44	2	36	112	233	309	2e-11	71.2
rs:XP_008731524	histidinol dehydrogenase [Cladophialophora carrionii CBS 160.54].	41.03	78	44	2	36	112	233	309	2e-11	71.2
tr:A0A0C3BWF1_9HOMO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIM90878.1};	39.56	91	52	3	24	112	190	279	2e-11	70.9
tr:A0A0D2GKI9_9EURO	SubName: Full=Unplaced genomic scaffold supercont1.3, whole genome shotgun sequence {ECO:0000313|EMBL:KIW81373.1};	41.03	78	44	2	36	112	233	309	2e-11	70.9
rs:XP_007329008	hypothetical protein AGABI1DRAFT_72979 [Agaricus bisporus var. burnettii JB137-S8].	38.20	89	52	3	25	112	193	279	2e-11	70.9
tr:A0A0D2H255_9EURO	SubName: Full=Rhinocladiella mackenziei CBS 650.93 unplaced genomic scaffold supercont1.4, whole genome shotgun sequence {ECO:0000313|EMBL:KIX04483.1};	34.11	129	60	5	8	112	182	309	2e-11	70.9
rs:WP_022080979	histidine biosynthesis bifunctional protein hisIE [Ruminococcus sp. CAG:488].	37.08	89	54	2	26	112	14	102	2e-11	67.0
tr:A0A093V8Z7_PENMA	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:KFX48660.1};	41.11	90	50	3	24	112	202	289	2e-11	70.9
tr:A0A017SRY2_9EURO	SubName: Full=Putative phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:EYE99025.1};	41.11	90	50	3	24	112	206	293	2e-11	70.9
rs:XP_006460280	hypothetical protein AGABI2DRAFT_184772 [Agaricus bisporus var. bisporus H97].	38.20	89	52	3	25	112	193	279	2e-11	70.9
tr:W1FTW5_ECOLX	RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000256|HAMAP-Rule:MF_01020}; Short=PRA-PH {ECO:0000256|HAMAP-Rule:MF_01020}; EC=3.6.1.31 {ECO:0000256|HAMAP-Rule:MF_01020};	43.04	79	35	1	58	126	1	79	2e-11	67.4
tr:A0A0B8PGV1_9VIBR	RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000256|HAMAP-Rule:MF_01020}; Short=PRA-PH {ECO:0000256|HAMAP-Rule:MF_01020}; EC=3.6.1.31 {ECO:0000256|HAMAP-Rule:MF_01020};	49.09	55	28	0	58	112	1	55	3e-11	67.4
tr:A0A0B4HP73_9HYPO	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:KIE01256.1}; Flags: Fragment;	39.36	94	55	2	22	115	202	293	3e-11	70.9
rs:XP_007588891	putative tri-functional histidine biosynthesis protein [Neofusicoccum parvum UCRNP2].	42.22	90	49	3	24	112	208	295	3e-11	70.9
tr:A1DRK3_9PLEO	SubName: Full=Tri-functional histidine biosynthesis protein {ECO:0000313|EMBL:ABL63163.1}; EC=1.1.1.23 {ECO:0000313|EMBL:ABL63163.1}; EC=3.5.4.19 {ECO:0000313|EMBL:ABL63163.1}; EC=3.6.1.31 {ECO:0000313|EMBL:ABL63163.1};	41.11	90	50	3	24	112	206	293	3e-11	70.9
rs:XP_001268804	phosphoribosyl-AMP cyclohydrolase, putative [Aspergillus clavatus NRRL 1].	44.87	78	41	2	36	112	219	295	3e-11	70.9
rs:XP_005791175	hypothetical protein EMIHUDRAFT_57193, partial [Emiliania huxleyi CCMP1516].	34.62	104	61	2	25	121	11	114	3e-11	66.6
tr:A0A0B4HCB4_9HYPO	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:KID89787.1};	39.36	94	55	2	22	115	202	293	3e-11	70.9
tr:A0A0B4H622_9HYPO	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:KID75309.1}; Flags: Fragment;	39.36	94	55	2	22	115	202	293	3e-11	70.9
tr:K9FIP0_PEND1	SubName: Full=Phosphoribosyl-AMP cyclohydrolase, putative {ECO:0000313|EMBL:EKV09129.1};	37.14	105	64	2	9	112	191	294	3e-11	70.9
rs:XP_007685657	hypothetical protein COCMIDRAFT_24317 [Bipolaris oryzae ATCC 44560].	42.22	90	49	3	24	112	200	287	3e-11	70.5
tr:M2TYH0_COCH5	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EMD86861.1};	42.22	90	49	3	24	112	200	287	3e-11	70.5
rs:XP_003019709	hypothetical protein TRV_06267, partial [Trichophyton verrucosum HKI 0517].	38.39	112	60	3	9	112	181	291	3e-11	70.5
rs:WP_022475926	phosphoribosyl-AMP cyclohydrolase [Ruminococcus sp. CAG:353].	30.93	97	62	2	22	113	23	119	3e-11	67.0
tr:A1DRK2_9PLEO	SubName: Full=Tri-functional histidine biosynthesis protein {ECO:0000313|EMBL:ABL63162.1}; EC=1.1.1.23 {ECO:0000313|EMBL:ABL63162.1}; EC=3.5.4.19 {ECO:0000313|EMBL:ABL63162.1}; EC=3.6.1.31 {ECO:0000313|EMBL:ABL63162.1};	41.11	90	50	3	24	112	206	293	3e-11	70.5
tr:A0A0B4F3H9_METAN	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:KID60426.1}; Flags: Fragment;	39.36	94	55	2	22	115	202	293	3e-11	70.5
rs:XP_007816902	histidinol dehydrogenase [Metarhizium robertsii ARSEF 23].	39.36	94	55	2	22	115	202	293	3e-11	70.5
rs:XP_002561712	Pc16g14140 [Penicillium rubens Wisconsin 54-1255].	37.14	105	64	2	9	112	193	296	3e-11	70.5
tr:W7EP54_COCVI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EUN28774.1};	42.22	90	49	3	24	112	200	287	3e-11	70.5
rs:XP_008020570	hypothetical protein SETTUDRAFT_162048 [Setosphaeria turcica Et28A].	46.67	75	38	2	39	112	215	288	3e-11	70.5
rs:XP_001264300	phosphoribosyl-AMP cyclohydrolase, putative [Neosartorya fischeri NRRL 181].	44.87	78	41	2	36	112	218	294	3e-11	70.5
tr:A0A0A2JUF8_PENEN	SubName: Full=Histidine biosynthesis trifunctional-protein {ECO:0000313|EMBL:KGO55855.1};	37.14	105	64	2	9	112	192	295	3e-11	70.5
rs:XP_007704624	hypothetical protein COCSADRAFT_184845 [Bipolaris sorokiniana ND90Pr].	42.22	90	49	3	24	112	200	287	3e-11	70.5
rs:XP_007714549	hypothetical protein COCCADRAFT_6922 [Bipolaris zeicola 26-R-13].	42.22	90	49	3	24	112	200	287	3e-11	70.5
tr:A0A084BP59_ASPFM	SubName: Full=Phosphoribosyl AMP cyclohydrolase {ECO:0000313|EMBL:KEY79338.1};	44.87	78	41	2	36	112	218	294	4e-11	70.5
rs:XP_752826	phosphoribosyl-AMP cyclohydrolase [Aspergillus fumigatus Af293].	44.87	78	41	2	36	112	218	294	4e-11	70.5
tr:A0A0C3QA78_9HOMO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIO27105.1};	40.66	91	51	3	24	112	197	286	4e-11	70.1
tr:M5GAW7_DACSP	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJU06044.1};	41.76	91	50	3	24	112	38	127	4e-11	70.1
rs:XP_003013587	hypothetical protein ARB_00034 [Arthroderma benhamiae CBS 112371].	37.50	112	61	3	9	112	181	291	4e-11	70.1
tr:A0A0C9WNV6_9AGAR	SubName: Full=Unplaced genomic scaffold K443scaffold_113, whole genome shotgun sequence {ECO:0000313|EMBL:KIJ99399.1};	40.45	89	50	3	25	112	194	280	4e-11	70.1
tr:F2PRD1_TRIEC	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:EGE04449.1};	37.50	112	61	3	9	112	181	291	4e-11	70.1
tr:F2RZR4_TRIT1	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:EGD96863.1};	37.50	112	61	3	9	112	181	291	5e-11	70.1
tr:A0A059JII1_9EURO	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:KDB27604.1};	37.50	112	61	3	9	112	181	291	5e-11	70.1
rs:WP_018284424	hypothetical protein, partial [zeta proteobacterium SCGC AB-137-J06].	58.14	43	18	0	71	113	1	43	5e-11	64.7
tr:W1FPZ9_ENTCL	RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000256|HAMAP-Rule:MF_01020}; Short=PRA-PH {ECO:0000256|HAMAP-Rule:MF_01020}; EC=3.6.1.31 {ECO:0000256|HAMAP-Rule:MF_01020};	49.09	55	28	0	58	112	1	55	5e-11	66.2
rs:XP_001934992	histidine biosynthesis trifunctional protein [Pyrenophora tritici-repentis Pt-1C-BFP].	42.22	90	49	3	24	112	206	293	5e-11	69.7
tr:A0A0C4ET58_PUCT1	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblFungi:PTTG_03987P0};	40.24	82	47	1	33	112	196	277	5e-11	69.7
tr:A0A0A2W0B8_BEABA	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:KGQ12052.1};	41.30	92	52	2	24	115	203	292	6e-11	69.7
rs:XP_008593635	histidinol dehydrogenase [Beauveria bassiana ARSEF 2860].	41.30	92	52	2	24	115	203	292	6e-11	69.7
rs:XP_002186010	predicted protein, partial [Phaeodactylum tricornutum CCAP 1055/1].	43.37	83	44	1	35	114	16	98	6e-11	66.6
rs:XP_003231785	histidinol dehydrogenase [Trichophyton rubrum CBS 118892].	37.50	112	61	3	9	112	181	291	6e-11	69.7
tr:A0A068VKJ1_COFCA	SubName: Full=Coffea canephora DH200=94 genomic scaffold, scaffold_2780 {ECO:0000313|EMBL:CDP21201.1};	34.62	78	51	0	40	117	1	78	6e-11	66.6
tr:A0A023ATJ2_TRIRU	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:EZG20950.1};	37.50	112	61	3	9	112	182	292	6e-11	69.7
rs:XP_004333513	histidinol dehydrogenase [Acanthamoeba castellanii str. Neff].	40.00	90	51	3	24	112	734	821	6e-11	70.1
rs:WP_043504432	phosphoribosyl-AMP cyclohydrolase, partial [Georgenia sp. SUBG003].	50.00	58	29	0	15	72	12	69	6e-11	64.7
tr:S7Z5L6_PENO1	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPS25399.1};	43.75	80	43	2	36	114	215	293	6e-11	69.7
tr:A0A063BL73_9HYPO	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:KDB11321.1};	40.43	94	54	2	22	115	202	293	6e-11	69.7
rs:XP_001876711	predicted protein [Laccaria bicolor S238N-H82].	39.33	89	51	3	25	112	194	280	6e-11	69.7
tr:A0A023ARM8_TRIRU	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:EZG20949.1};	37.50	112	61	3	9	112	182	292	7e-11	69.7
tr:A0A0D9M9A2_9EURO	SubName: Full=Histidine biosynthesis trifunctional-protein {ECO:0000313|EMBL:KJJ23338.1};	37.14	105	64	2	9	112	192	295	7e-11	69.7
rs:XP_003304863	hypothetical protein PTT_17572 [Pyrenophora teres f. teres 0-1].	42.22	90	49	3	24	112	206	293	7e-11	69.7
rs:XP_658401	hypothetical protein AN0797.2 [Aspergillus nidulans FGSC A4].	43.59	78	42	2	36	112	217	293	7e-11	69.3
tr:K2S774_MACPH	SubName: Full=Histidinol dehydrogenase conserved site {ECO:0000313|EMBL:EKG18244.1};	41.11	90	50	3	24	112	207	294	8e-11	69.3
tr:W4MBC1_9DELT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETX07659.1}; Flags: Fragment;	39.29	84	44	2	47	123	2	85	8e-11	64.7
rs:XP_011111919	hypothetical protein H072_6118 [Dactylellina haptotyla CBS 200.50].	39.81	103	59	3	24	125	212	312	9e-11	69.3
rs:XP_012182460	predicted protein [Fibroporia radiculosa].	38.46	91	53	3	24	112	191	280	9e-11	69.3
rs:XP_006966696	histidinol dehydrogenase [Trichoderma reesei QM6a].	40.45	89	51	2	24	112	204	290	1e-10	68.9
tr:G9P9U5_HYPAI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHK40417.1};	40.45	89	51	2	24	112	170	256	1e-10	68.9
tr:A0A0D9Q636_METAN	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:KJK93761.1};	38.30	94	56	2	22	115	202	293	1e-10	68.9
tr:G9MIH7_HYPVG	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHK25294.1};	40.45	89	51	2	24	112	204	290	1e-10	68.9
tr:A0A0A1SWL0_9HYPO	SubName: Full=Putative Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:CEJ88936.1};	38.20	89	53	2	24	112	204	290	1e-10	68.9
tr:M1WE23_CLAP2	SubName: Full=Probable histidine biosynthesis trifunctional protein (His-3) {ECO:0000313|EMBL:CCE29809.1};	40.22	92	53	2	24	115	204	293	1e-10	68.9
tr:U5HA46_USTV1	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDE05586.1, ECO:0000313|EnsemblFungi:MVLG_04081T0};	36.28	113	63	4	9	112	204	316	1e-10	68.9
rs:WP_017955680	hypothetical protein, partial [actinobacterium SCGC AAA278-O22].	59.57	47	19	0	71	117	1	47	1e-10	63.2
rs:XP_007291409	histidinol dehydrogenase [Marssonina brunnea f. sp. 'multigermtubi' MB_m1].	39.13	92	53	3	22	112	200	289	1e-10	68.6
rs:XP_004364065	hypothetical protein CAOG_03226 [Capsaspora owczarzaki ATCC 30864].	43.59	78	42	2	36	112	218	294	1e-10	68.6
rs:XP_001587239	hypothetical protein SS1G_12269 [Sclerotinia sclerotiorum 1980 UF-70].	40.45	89	50	3	25	112	203	289	1e-10	68.6
rs:XP_006670632	histidine biosynthesis trifunctional protein [Cordyceps militaris CM01].	40.22	92	53	2	24	115	203	292	1e-10	68.6
tr:W6QYT9_PENRO	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:CDM34712.1};	36.19	105	65	2	9	112	192	295	1e-10	68.6
rs:XP_010762219	histidinol dehydrogenase [Paracoccidioides brasiliensis Pb18].	41.11	90	50	3	24	112	210	297	1e-10	68.6
tr:C0SE67_PARBP	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:EEH15885.1};	41.11	90	50	3	24	112	211	298	1e-10	68.6
tr:A0A028K0M7_TRIRU	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:EZG10280.1};	36.61	112	62	3	9	112	182	292	1e-10	68.6
tr:R4XBM1_TAPDE	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:CCG80733.1};	41.11	90	50	3	24	112	180	267	2e-10	68.6
rs:XP_003177463	histidine biosynthesis trifunctional protein [Microsporum gypseum CBS 118893].	37.50	112	61	3	9	112	181	291	2e-10	68.6
rs:XP_003853594	hypothetical protein MYCGRDRAFT_70608 [Zymoseptoria tritici IPO323].	42.22	90	49	3	24	112	211	298	2e-10	68.6
tr:D4DT76_NEIEG	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:EFE48924.1}; EC=3.5.4.19 {ECO:0000313|EMBL:EFE48924.1};	48.44	64	31	2	70	131	1	64	2e-10	63.5
tr:A0A0B2WV43_9HYPO	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:KHN96755.1};	37.23	94	57	2	22	115	202	293	2e-10	68.6
tr:A0A028JZV3_TRIRU	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:EZG10279.1};	36.61	112	62	3	9	112	182	292	2e-10	68.6
tr:A0A0A2LEJ8_PENIT	SubName: Full=Histidine biosynthesis trifunctional-protein {ECO:0000313|EMBL:KGO75070.1};	36.19	105	65	2	9	112	192	295	2e-10	68.6
tr:A0A0D0BTS9_9HOMO	SubName: Full=Unplaced genomic scaffold CY34scaffold_4, whole genome shotgun sequence {ECO:0000313|EMBL:KIK48957.1};	39.56	91	52	3	24	112	193	282	2e-10	68.2
rs:XP_002841325	hypothetical protein [Tuber melanosporum Mel28].	42.70	89	48	3	25	112	205	291	2e-10	67.0
tr:N4V8J3_COLOR	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:ENH77291.1};	39.33	89	52	2	24	112	206	292	2e-10	68.2
tr:A0A0D2BBR3_9PEZI	SubName: Full=Verruconis gallopava strain CBS 43764 unplaced genomic scaffold supercont1.2, whole genome shotgun sequence {ECO:0000313|EMBL:KIW08819.1};	40.22	92	52	3	22	112	205	294	2e-10	68.2
rs:XP_009830738	phosphoribosyl-ATP diphosphatase [Aphanomyces astaci].	38.14	97	50	3	24	111	191	286	2e-10	67.4
rs:XP_007926351	hypothetical protein MYCFIDRAFT_87720 [Pseudocercospora fijiensis CIRAD86].	42.22	90	49	3	24	112	211	298	2e-10	68.2
tr:A1DRK1_PHAND	SubName: Full=Tri-functional histidine biosynthesis protein {ECO:0000313|EMBL:ABL63161.1}; EC=1.1.1.23 {ECO:0000313|EMBL:ABL63161.1}; EC=3.5.4.19 {ECO:0000313|EMBL:ABL63161.1}; EC=3.6.1.31 {ECO:0000313|EMBL:ABL63161.1};	40.00	90	51	3	24	112	206	293	2e-10	68.2
tr:A1DRK0_PHAND	SubName: Full=Tri-functional histidine biosynthesis protein {ECO:0000313|EMBL:ABL63160.1}; EC=1.1.1.23 {ECO:0000313|EMBL:ABL63160.1}; EC=3.5.4.19 {ECO:0000313|EMBL:ABL63160.1}; EC=3.6.1.31 {ECO:0000313|EMBL:ABL63160.1};	40.00	90	51	3	24	112	206	293	2e-10	68.2
tr:X1T6T7_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_L01770 {ECO:0000313|EMBL:GAI75734.1}; Flags: Fragment;	53.06	49	23	0	16	64	8	56	2e-10	62.8
tr:W9CU67_9HELO	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:ESZ98129.1};	39.33	89	51	3	25	112	203	289	2e-10	68.2
tr:A1DRK5_9PLEO	SubName: Full=Tri-functional histidine biosynthesis protein {ECO:0000313|EMBL:ABL63165.1}; EC=1.1.1.23 {ECO:0000313|EMBL:ABL63165.1}; EC=3.5.4.19 {ECO:0000313|EMBL:ABL63165.1}; EC=3.6.1.31 {ECO:0000313|EMBL:ABL63165.1};	40.00	90	51	3	24	112	206	293	2e-10	67.8
rs:XP_001801645	hypothetical protein SNOG_11402 [Phaeosphaeria nodorum SN15].	40.00	90	51	3	24	112	206	293	2e-10	68.2
tr:A1DRJ2_PHAND	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:ABM67560.1}; EC=1.1.1.23 {ECO:0000313|EMBL:ABM67560.1}; EC=3.5.4.19 {ECO:0000313|EMBL:ABM67560.1}; EC=3.6.1.31 {ECO:0000313|EMBL:ABM67560.1}; SubName: Full=Tri-functional histidine biosynthesis protein {ECO:0000313|EMBL:ABL63152.1}; EC=1.1.1.23 {ECO:0000313|EMBL:ABL63152.1}; EC=3.5.4.19 {ECO:0000313|EMBL:ABL63152.1}; EC=3.6.1.31 {ECO:0000313|EMBL:ABL63152.1};	40.00	90	51	3	24	112	206	293	2e-10	67.8
tr:Q2PPB3_PHAND	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:ABC40952.1}; EC=1.1.1.23 {ECO:0000313|EMBL:ABM67561.1}; EC=3.5.4.19 {ECO:0000313|EMBL:ABM67561.1}; EC=3.6.1.31 {ECO:0000313|EMBL:ABM67561.1};	40.00	90	51	3	24	112	206	293	2e-10	67.8
tr:A0A0D9N5Y8_ASPFL	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:KJJ35519.1};	42.31	78	43	2	36	112	215	291	2e-10	67.8
tr:F2TC80_AJEDA	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:EGE80843.1};	41.11	90	50	3	24	112	214	301	2e-10	67.8
tr:T5C8Z4_AJEDE	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:EQL37945.1};	41.11	90	50	3	24	112	214	301	2e-10	67.8
tr:A2IBN3_PHAND	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:ABM67562.1}; EC=1.1.1.23 {ECO:0000313|EMBL:ABM67562.1}; EC=3.5.4.19 {ECO:0000313|EMBL:ABM67562.1}; EC=3.6.1.31 {ECO:0000313|EMBL:ABM67562.1};	40.00	90	51	3	24	112	206	293	2e-10	67.8
rs:XP_002623615	histidinol dehydrogenase [Blastomyces dermatitidis SLH14081].	41.11	90	50	3	24	112	214	301	2e-10	67.8
rs:XP_007732440	histidinol dehydrogenase [Capronia epimyces CBS 606.96].	40.00	75	43	2	39	112	236	309	3e-10	67.8
rs:XP_007337928	histidine biosynthesis trifunctional-protein [Auricularia delicata TFB-10046 SS5].	38.46	91	53	3	24	112	183	272	3e-10	67.8
rs:XP_002850321	histidinol dehydrogenase [Arthroderma otae CBS 113480].	36.61	112	62	3	9	112	182	292	3e-10	67.8
rs:XP_007007281	hypothetical protein TREMEDRAFT_40724 [Tremella mesenterica DSM 1558].	38.61	101	57	4	24	123	183	279	3e-10	67.8
rs:XP_007767578	histidine biosynthesis trifunctional-protein [Coniophora puteana RWD-64-598 SS2].	39.56	91	52	3	24	112	187	276	3e-10	67.8
tr:A1DRJ3_9PLEO	SubName: Full=Tri-functional histidine biosynthesis protein {ECO:0000313|EMBL:ABL63153.1}; EC=1.1.1.23 {ECO:0000313|EMBL:ABL63153.1}; EC=3.5.4.19 {ECO:0000313|EMBL:ABL63153.1}; EC=3.6.1.31 {ECO:0000313|EMBL:ABL63153.1};	40.00	90	51	3	24	112	206	293	3e-10	67.8
rs:XP_011127066	hypothetical protein AOL_s00193g153 [Arthrobotrys oligospora ATCC 24927].	40.66	91	52	2	36	125	227	316	3e-10	67.8
tr:A1DRK6_9PLEO	SubName: Full=Tri-functional histidine biosynthesis protein {ECO:0000313|EMBL:ABL63166.1}; EC=1.1.1.23 {ECO:0000313|EMBL:ABL63166.1}; EC=3.5.4.19 {ECO:0000313|EMBL:ABL63166.1}; EC=3.6.1.31 {ECO:0000313|EMBL:ABL63166.1};	40.00	90	51	3	24	112	206	293	3e-10	67.8
rs:XP_002792677	histidine biosynthesis trifunctional protein [Paracoccidioides sp. 'lutzii' Pb01].	41.11	90	50	3	24	112	210	297	3e-10	67.8
tr:J5Q8Y6_TRIAS	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:EJT46103.1};	38.46	91	53	3	24	112	185	274	3e-10	67.4
tr:A0A0D0A7Z1_9HOMO	SubName: Full=Unplaced genomic scaffold scaffold_2, whole genome shotgun sequence {ECO:0000313|EMBL:KIK30542.1};	37.36	91	54	3	24	112	189	278	3e-10	67.4
tr:A1DRJ6_9PLEO	SubName: Full=Tri-functional histidine biosynthesis protein {ECO:0000313|EMBL:ABL63156.1}; EC=1.1.1.23 {ECO:0000313|EMBL:ABL63156.1}; EC=3.5.4.19 {ECO:0000313|EMBL:ABL63156.1}; EC=3.6.1.31 {ECO:0000313|EMBL:ABL63156.1};	40.00	90	51	3	24	112	206	293	3e-10	67.4
tr:A0A086T2A3_ACRCH	SubName: Full=Histidine biosynthesis trifunctional protein-like protein {ECO:0000313|EMBL:KFH43485.1};	39.33	89	52	2	24	112	204	290	3e-10	67.4
tr:A1DRJ7_9PLEO	SubName: Full=Tri-functional histidine biosynthesis protein {ECO:0000313|EMBL:ABL63157.1}; EC=1.1.1.23 {ECO:0000313|EMBL:ABL63157.1}; EC=3.5.4.19 {ECO:0000313|EMBL:ABL63157.1}; EC=3.6.1.31 {ECO:0000313|EMBL:ABL63157.1};	40.00	90	51	3	24	112	206	293	3e-10	67.4
tr:A1DRJ8_9PLEO	SubName: Full=Tri-functional histidine biosynthesis protein {ECO:0000313|EMBL:ABL63158.1}; EC=1.1.1.23 {ECO:0000313|EMBL:ABL63158.1}; EC=3.5.4.19 {ECO:0000313|EMBL:ABL63158.1}; EC=3.6.1.31 {ECO:0000313|EMBL:ABL63158.1};	40.00	90	51	3	24	112	206	293	3e-10	67.4
tr:W7LAU5_GIBM7	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:EWG36723.1};	39.33	89	52	2	24	112	197	283	3e-10	67.4
rs:XP_002374849	phosphoribosyl-AMP cyclohydrolase, putative [Aspergillus flavus NRRL3357].	42.31	78	43	2	36	112	215	291	3e-10	67.4
tr:N1JLP0_BLUG1	SubName: Full=His-3/histidine-3 protein/tri-functional histidine biosynthesis protein {ECO:0000313|EMBL:CCU81490.1};	37.89	95	56	3	22	115	203	295	3e-10	66.6
tr:L8X688_THACA	SubName: Full=His4p {ECO:0000313|EMBL:ELU45715.1};	40.66	91	51	3	24	112	523	612	3e-10	67.4
rs:XP_009856318	histidine biosynthesis trifunctional protein [Neurospora tetrasperma FGSC 2508].	40.22	92	53	2	24	115	208	297	4e-10	67.4
tr:A0A060SA95_PYCCI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CDO71260.1};	38.46	91	53	3	24	112	198	287	4e-10	67.4
tr:A0A0A8L3G2_9SACH	SubName: Full=WGS project CCBQ000000000 data, contig MAT {ECO:0000313|EMBL:CDO92720.1};	31.45	124	72	2	2	112	113	236	4e-10	67.4
tr:K1VUS2_TRIAC	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:EKD04251.1};	38.46	91	53	3	24	112	185	274	4e-10	67.4
tr:A1DRK4_PHAND	SubName: Full=Tri-functional histidine biosynthesis protein {ECO:0000313|EMBL:ABL63164.1}; EC=1.1.1.23 {ECO:0000313|EMBL:ABL63164.1}; EC=3.5.4.19 {ECO:0000313|EMBL:ABL63164.1}; EC=3.6.1.31 {ECO:0000313|EMBL:ABL63164.1};	40.00	90	51	3	24	112	206	293	4e-10	67.4
tr:A0A094AQS5_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY31916.1};	39.33	89	51	3	25	112	202	288	4e-10	67.4
tr:A0A061HGC1_BLUGR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPQ64347.1};	37.89	95	56	3	22	115	203	295	4e-10	66.6
rs:XP_007844692	histidinol dehydrogenase [Moniliophthora roreri MCA 2997].	36.67	90	54	3	24	112	191	278	4e-10	67.4
tr:A1DRK7_9PLEO	SubName: Full=Tri-functional histidine biosynthesis protein {ECO:0000313|EMBL:ABL63167.1}; EC=1.1.1.23 {ECO:0000313|EMBL:ABL63167.1}; EC=3.5.4.19 {ECO:0000313|EMBL:ABL63167.1}; EC=3.6.1.31 {ECO:0000313|EMBL:ABL63167.1};	40.00	90	51	3	24	112	206	293	4e-10	67.4
tr:U4LIL8_PYROM	SubName: Full=Similar to Histidine biosynthesis trifunctional protein acc. no. P07685 {ECO:0000313|EMBL:CCX31367.1};	42.39	92	50	3	22	112	188	277	4e-10	67.4
rs:XP_001542186	histidinol dehydrogenase [Histoplasma capsulatum NAm1].	40.00	90	51	3	24	112	211	298	4e-10	67.4
tr:S0DK52_GIBF5	SubName: Full=Probable histidine biosynthesis trifunctional protein (His-3) {ECO:0000313|EMBL:CCT62736.1};	39.33	89	52	2	24	112	197	283	4e-10	67.0
tr:X0M414_FUSOX	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:EXM28116.1};	39.33	89	52	2	24	112	197	283	5e-10	67.0
rs:XP_008035744	histidine biosynthesis trifunctional-protein [Trametes versicolor FP-101664 SS1].	38.46	91	53	3	24	112	197	286	5e-10	67.0
rs:XP_003054494	predicted protein [Nectria haematococca mpVI 77-13-4].	39.33	89	52	2	24	112	197	283	5e-10	67.0
tr:C0NEX3_AJECG	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:EEH09794.1};	41.11	90	50	3	24	112	211	298	5e-10	67.0
tr:X0BVA3_FUSOX	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:EXK48801.1};	39.33	89	52	2	24	112	197	283	5e-10	67.0
tr:X0CX53_FUSOX	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:EXK95868.1};	39.33	89	52	2	24	112	197	283	5e-10	67.0
tr:W9MAV6_FUSOX	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:EWZ91015.1};	39.33	89	52	2	24	112	197	283	5e-10	67.0
tr:F9G069_FUSOF	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGU77438.1};	39.33	89	52	2	24	112	197	283	5e-10	67.0
rs:XP_006959322	histidine biosynthesis trifunctional-protein [Wallemia sebi CBS 633.66].	37.89	95	57	2	36	129	202	295	5e-10	67.0
tr:A0A094HSZ6_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFZ18560.1};	39.33	89	51	3	25	112	202	288	5e-10	67.0
rs:XP_007412818	hypothetical protein MELLADRAFT_72470 [Melampsora larici-populina 98AG31].	42.31	78	41	2	38	112	222	298	5e-10	67.0
tr:A0A094EXF7_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY76320.1};	39.33	89	51	3	25	112	202	288	6e-10	67.0
tr:G7DZ80_MIXOS	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:GAA95890.1};	43.75	80	42	2	39	115	235	314	6e-10	66.6
tr:F0UG54_AJEC8	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:EGC44260.1};	41.11	90	50	3	24	112	211	298	6e-10	66.6
tr:C6HNT6_AJECH	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:EER38132.1};	41.11	90	50	3	24	112	211	298	6e-10	66.6
tr:J7R2W3_KAZNA	SubName: Full=KNAG0C00510 protein {ECO:0000313|EMBL:CCK69165.1};	40.00	75	44	1	39	112	144	218	7e-10	66.6
rs:XP_001559723	hypothetical protein BC1G_01879 [Botrytis cinerea B05.10].	38.20	89	52	3	25	112	203	289	8e-10	66.2
tr:G4TVC0_PIRID	SubName: Full=Related to HIS-3 histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:CCA75263.1};	41.11	90	52	1	24	112	226	315	8e-10	66.2
tr:M6TT71_LEPIR	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	37.93	87	51	2	6	90	56	141	8e-10	62.8
tr:A0A0D1Y585_9EURO	SubName: Full=Strain CBS 40295 unplaced genomic scaffold supercont1.2, whole genome shotgun sequence {ECO:0000313|EMBL:KIV95856.1};	40.00	75	43	2	39	112	236	309	8e-10	66.2
tr:A0A067MMI4_9HOMO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDQ12781.1};	39.56	91	52	3	24	112	196	285	8e-10	66.2
tr:A0A094HDP0_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFZ11524.1};	38.20	89	52	3	25	112	201	287	9e-10	66.2
tr:A0A084G4S0_9PEZI	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:KEZ42332.1};	39.13	92	54	2	24	115	205	294	9e-10	66.2
rs:XP_008875308	phosphoribosyl-ATP diphosphatase [Aphanomyces invadans].	35.05	97	53	2	24	111	193	288	9e-10	65.5
tr:S9Q4A7_SCHOY	SubName: Full=Phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase His7 {ECO:0000313|EMBL:EPX74493.1};	42.31	78	43	2	36	112	221	297	1e-09	65.5
rs:XP_009263034	hypothetical protein FPSE_11642 [Fusarium pseudograminearum CS3096].	38.20	89	53	2	24	112	197	283	1e-09	65.9
rs:XP_002582368	histidine biosynthesis protein [Uncinocarpus reesii 1704].	39.08	87	51	2	15	101	198	282	1e-09	65.9
rs:XP_011102666	his4p [Saccharomyces arboricola H-6].	38.67	75	45	1	39	112	164	238	1e-09	65.9
tr:S9XAF8_SCHCR	SubName: Full=Phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase His7 {ECO:0000313|EMBL:EPY54142.1};	43.59	78	42	2	36	112	221	297	1e-09	65.1
rs:XP_007206929	hypothetical protein PRUPE_ppb015252mg [Prunus persica].	38.16	76	46	1	17	92	26	100	1e-09	62.4
sp:HIS2_KLULA	RecName: Full=Histidine biosynthesis trifunctional protein; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphohydrolase; EC=3.6.1.31; Includes: RecName: Full=Histidinol dehydrogenase; Short=HDH; EC=1.1.1.23;	42.11	76	42	1	39	112	159	234	1e-09	65.9
tr:V5GCU4_BYSSN	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:GAD98747.1};	42.31	78	43	2	36	112	216	292	1e-09	65.9
rs:XP_009268880	Histidine biosynthesis trifunctional protein [Wallemia ichthyophaga EXF-994].	36.84	95	58	2	36	129	203	296	1e-09	65.9
rs:WP_046400434	phosphoribosyl-ATP pyrophosphatase, partial [Staphylococcus aureus].	49.02	51	26	0	66	116	1	51	1e-09	62.4
tr:A0A094G741_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY98889.1};	38.20	89	52	3	25	112	201	287	1e-09	65.9
rs:XP_011316592	histidine biosynthesis trifunctional protein [Fusarium graminearum PH-1].	38.20	89	53	2	24	112	197	283	1e-09	65.9
sp:HIS2_SCHPO	RecName: Full=Histidine biosynthesis bifunctional protein his7 {ECO:0000250|UniProtKB:P00815, ECO:0000312|EMBL:CAA18379.1}; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000250|UniProtKB:P00815}; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphatase {ECO:0000250|UniProtKB:P00815}; EC=3.6.1.31;	37.76	98	47	3	16	112	213	297	1e-09	65.1
tr:A0A0C5QW81_YEASX	SubName: Full=HIS4 protein {ECO:0000313|EMBL:AJQ39911.1};	38.67	75	45	1	39	112	164	238	1e-09	65.5
tr:A0A0C5QPS5_YEASX	SubName: Full=HIS4 protein {ECO:0000313|EMBL:AJQ33059.1};	38.67	75	45	1	39	112	164	238	1e-09	65.5
tr:A0A0C5QX60_YEASX	SubName: Full=HIS4 protein {ECO:0000313|EMBL:AJQ36998.1};	38.67	75	45	1	39	112	164	238	1e-09	65.5
tr:A0A0C5RKP8_YEASX	SubName: Full=HIS4 protein {ECO:0000313|EMBL:AJQ39760.1};	38.67	75	45	1	39	112	164	238	1e-09	65.5
tr:A0A0C5RIQ4_YEASX	SubName: Full=HIS4 protein {ECO:0000313|EMBL:AJQ43374.1};	38.67	75	45	1	39	112	164	238	1e-09	65.5
tr:A0A0C5QNK3_YEASX	SubName: Full=HIS4 protein {ECO:0000313|EMBL:AJQ33928.1};	38.67	75	45	1	39	112	164	238	1e-09	65.5
tr:A0A0C5R8J7_YEASX	SubName: Full=HIS4 protein {ECO:0000313|EMBL:AJQ40637.1};	38.67	75	45	1	39	112	164	238	1e-09	65.5
tr:A0A0C5R0E8_YEASX	SubName: Full=HIS4 protein {ECO:0000313|EMBL:AJQ41506.1};	38.67	75	45	1	39	112	164	238	1e-09	65.5
tr:A0A0C5QUR3_YEASX	SubName: Full=HIS4 protein {ECO:0000313|EMBL:AJQ35687.1};	38.67	75	45	1	39	112	164	238	1e-09	65.5
tr:G2W9Z5_YEASK	SubName: Full=K7_His4p {ECO:0000313|EMBL:GAA21888.1};	38.67	75	45	1	39	112	164	238	1e-09	65.5
tr:A0A0C5QQK7_YEASX	SubName: Full=HIS4 protein {ECO:0000313|EMBL:AJQ33349.1};	38.67	75	45	1	39	112	164	238	1e-09	65.5
tr:A0A0C5QJH8_YEASX	SubName: Full=HIS4 protein {ECO:0000313|EMBL:AJQ32042.1};	38.67	75	45	1	39	112	164	238	1e-09	65.5
tr:A0A0C5R9D3_YEASX	SubName: Full=HIS4 protein {ECO:0000313|EMBL:AJQ40204.1};	38.67	75	45	1	39	112	164	238	1e-09	65.5
tr:A0A0C5R0Q1_YEASX	SubName: Full=HIS4 protein {ECO:0000313|EMBL:AJQ38313.1};	38.67	75	45	1	39	112	164	238	1e-09	65.5
tr:A0A0D2RQU7_GOSRA	SubName: Full=Gossypium raimondii chromosome 6, whole genome shotgun sequence {ECO:0000313|EMBL:KJB34284.1};	29.73	111	69	2	9	118	55	157	1e-09	63.5
rs:XP_003348373	hypothetical protein SMAC_02870 [Sordaria macrospora k-hell].	39.13	92	54	2	24	115	208	297	1e-09	65.5
tr:A0A094HUZ6_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY88067.1};	37.08	89	53	3	25	112	202	288	1e-09	65.5
gp:AF045455_1	histidine-3 protein [Neurospora crassa]	39.13	92	54	2	24	115	208	297	1e-09	65.5
sp:HIS2_NEUCR	RecName: Full=Histidine biosynthesis trifunctional protein; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphohydrolase; EC=3.6.1.31; Includes: RecName: Full=Histidinol dehydrogenase; Short=HDH; EC=1.1.1.23;	39.13	92	54	2	24	115	208	297	1e-09	65.5
tr:G4U7K7_NEUT9	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:EGZ77503.1};	39.13	92	54	2	24	115	208	297	1e-09	65.5
tr:W0T294_KLUMA	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:BAO37687.1};	39.47	76	44	1	39	112	161	236	1e-09	65.5
tr:A0A090BHW9_KLUMA	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:BAP69258.1};	39.47	76	44	1	39	112	161	236	1e-09	65.5
gp:AF045456_1	histidine-3 protein [Neurospora crassa]	39.13	92	54	2	24	115	208	297	1e-09	65.5
rs:XP_002173606	phosphoribosyl-AMP cyclohydrolase/phosphoribosyl- ATP pyrophosphohydrolase His7 [Schizosaccharomyces japonicus yFS275].	39.74	78	45	2	36	112	219	295	2e-09	64.7
rs:XP_007366030	histidine biosynthesis trifunctional-protein [Dichomitus squalens LYAD-421 SS1].	36.56	93	56	3	24	114	197	288	2e-09	65.5
rs:XP_012742288	histidinol dehydrogenase [Pseudogymnoascus destructans 20631-21].	38.20	89	52	3	25	112	202	288	2e-09	65.5
gp:V01310_1	HIS4 protein [Saccharomyces cerevisiae]	38.67	75	45	1	39	112	164	238	2e-09	65.5
tr:H0GD26_SACCK	SubName: Full=His4p {ECO:0000313|EMBL:EHN08284.1};	38.67	75	45	1	39	112	164	238	2e-09	65.5
tr:A0A0C5RBQ8_YEASX	SubName: Full=HIS4 protein {ECO:0000313|EMBL:AJQ41069.1};	38.67	75	45	1	39	112	164	238	2e-09	65.5
tr:A0A0C5R748_YEASX	SubName: Full=HIS4 protein {ECO:0000313|EMBL:AJQ34960.1};	38.67	75	45	1	39	112	164	238	2e-09	65.5
tr:A0A0C5RHU6_YEASX	SubName: Full=HIS4 protein {ECO:0000313|EMBL:AJQ44233.1};	38.67	75	45	1	39	112	164	238	2e-09	65.5
tr:A0A0C5R2A8_YEASX	SubName: Full=HIS4 protein {ECO:0000313|EMBL:AJQ38903.1};	38.67	75	45	1	39	112	164	238	2e-09	65.5
sp:HIS2_YEAST	RecName: Full=Histidine biosynthesis trifunctional protein; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphohydrolase; EC=3.6.1.31; Includes: RecName: Full=Histidinol dehydrogenase; Short=HDH; EC=1.1.1.23;	38.67	75	45	1	39	112	164	238	2e-09	65.5
tr:E7KA08_YEASA	SubName: Full=His4p {ECO:0000313|EMBL:EGA75841.1};	38.67	75	45	1	39	112	164	238	2e-09	65.5
tr:A0A0C3KT90_PISTI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIO12727.1};	36.26	91	55	3	24	112	189	278	2e-09	65.5
tr:A0A0D0DQI8_9HOMO	SubName: Full=Unplaced genomic scaffold scaffold_268, whole genome shotgun sequence {ECO:0000313|EMBL:KIK94703.1};	37.25	102	61	3	13	112	173	273	2e-09	65.5
tr:M7PN95_9GAMM	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:EMR11944.1};	46.55	58	31	0	18	75	8	65	2e-09	61.6
tr:W9IEU7_FUSOX	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:EWY93182.1};	38.20	89	53	2	24	112	197	283	2e-09	65.1
rs:XP_001646828	hypothetical protein Kpol_2002p40 [Vanderwaltozyma polyspora DSM 70294].	36.17	94	56	2	25	115	153	245	2e-09	65.1
gp:AF114752_1	HMG1-SUC2-HIS4C protein [Shuttle vector pCS4-14]	38.67	75	45	1	39	112	989	1063	2e-09	65.5
tr:T0YR61_9ZZZZ	SubName: Full=Phosphoribosyl-AMP cyclohydrolase domain protein {ECO:0000313|EMBL:EQD35608.1}; EC=3.5.4.19 {ECO:0000313|EMBL:EQD35608.1}; Flags: Fragment;	50.00	50	25	0	24	73	8	57	2e-09	60.1
tr:A0A0B7FTY1_THACB	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:CEL59683.1}; EC=1.1.1.23 {ECO:0000313|EMBL:CEL59683.1};	39.56	91	52	3	24	112	194	283	2e-09	65.1
tr:X8JF83_9HOMO	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:EUC62319.1};	39.56	91	52	3	24	112	194	283	2e-09	65.1
sp:HIS2_SACBA	RecName: Full=Histidine biosynthesis trifunctional protein; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphohydrolase; EC=3.6.1.31; Includes: RecName: Full=Histidinol dehydrogenase; Short=HDH; EC=1.1.1.23;	37.33	75	46	1	39	112	164	238	2e-09	65.1
tr:A0A074SU79_9HOMO	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:KEP53482.1};	39.56	91	52	3	24	112	194	283	2e-09	65.1
rs:XP_011399970	Histidine biosynthesis bifunctional protein hisIE, chloroplastic [Auxenochlorella protothecoides].	42.65	68	36	1	58	122	210	277	2e-09	64.3
tr:A0A074WN37_9PEZI	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:KEQ74515.1};	38.89	90	52	3	24	112	205	292	2e-09	65.1
tr:M5C097_THACB	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:CCO32891.1}; EC=1.1.1.23 {ECO:0000313|EMBL:CCO32891.1};	39.56	91	52	3	24	112	194	283	2e-09	65.1
rs:XP_007268384	histidine biosynthesis trifunctional-protein [Fomitiporia mediterranea MF3/22].	37.36	91	54	3	24	112	194	283	2e-09	65.1
tr:K0RV56_THAOC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJK56895.1};	40.00	100	54	3	18	112	277	375	3e-09	64.3
tr:E7QC14_YEASZ	SubName: Full=His4p {ECO:0000313|EMBL:EGA87787.1};	38.67	75	45	1	39	112	164	238	3e-09	64.7
rs:XP_001220103	hypothetical protein CHGG_00882 [Chaetomium globosum CBS 148.51].	38.78	98	57	3	16	112	199	294	3e-09	64.7
gpu:LN483124_590	histidine biosynthesis trifunctional-protein [Xanthophyllomyces dendrorhous]	36.26	91	55	3	24	112	193	282	3e-09	64.7
tr:S8EFG9_FOMPI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPT03752.1};	36.26	91	55	3	24	112	193	282	3e-09	64.7
rs:XP_001749629	hypothetical protein [Monosiga brevicollis MX1].	35.78	109	68	2	5	112	96	203	3e-09	64.3
tr:W1Q6Q2_OGAPD	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:ESW95783.1}; EC=3.5.4.19 {ECO:0000313|EMBL:ESW95783.1};	36.67	90	54	3	24	112	175	262	3e-09	64.3
gp:Y09503_1	histidinol dehydrogenase [Kluyveromyces lactis]	44.29	70	37	1	45	112	165	234	4e-09	64.3
tr:M5E4F8_MALS4	SubName: Full=Genomic scaffold, msy_sf_1 {ECO:0000313|EMBL:CCU97519.1};	34.15	123	70	4	3	115	168	289	4e-09	64.3
tr:J6EHN5_SACK1	SubName: Full=HIS4-like protein {ECO:0000313|EMBL:EJT42897.1};	37.33	75	46	1	39	112	164	238	4e-09	64.3
tr:A0A0C3B0X5_9HOMO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIM25151.1};	36.67	90	55	2	24	112	193	281	4e-09	64.3
rs:XP_500110	YALI0A15950p [Yarrowia lipolytica].	36.96	92	55	3	22	112	193	282	4e-09	64.3
tr:A0A060TD23_BLAAD	SubName: Full=ARAD1B20724p {ECO:0000313|EMBL:CDP36777.1}; EC=1.1.1.23 {ECO:0000313|EMBL:CDP36777.1}; EC=3.5.4.19 {ECO:0000313|EMBL:CDP36777.1}; EC=3.6.1.31 {ECO:0000313|EMBL:CDP36777.1};	36.28	113	65	5	2	112	165	272	4e-09	64.3
tr:A0A0D7BUX8_9HOMO	SubName: Full=Histidine biosynthesis trifunctional-protein {ECO:0000313|EMBL:KIY74060.1};	36.67	90	54	3	24	112	187	274	4e-09	63.9
rs:XP_006696385	putative histidine biosynthesis trifunctional protein [Chaetomium thermophilum var. thermophilum DSM 1495].	39.33	89	52	2	24	112	207	293	5e-09	63.9
rs:XP_006676525	hypothetical protein BATDEDRAFT_9548 [Batrachochytrium dendrobatidis JAM81].	40.00	90	51	3	24	112	57	144	5e-09	63.9
tr:A0A099P1J3_ISSOR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGK38179.1};	33.00	100	54	3	25	112	2499	2597	5e-09	64.3
rs:XP_009657875	histidine biosynthesis trifunctional protein [Verticillium dahliae VdLs.17].	34.78	92	58	2	24	115	191	280	5e-09	63.9
rs:XP_009223883	histidine biosynthesis trifunctional protein [Gaeumannomyces graminis var. tritici R3-111a-1].	38.20	89	53	2	24	112	209	295	5e-09	63.9
tr:A0A015JDD6_9GLOM	SubName: Full=Trifunctional histidinol dehydrogenase/phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase {ECO:0000313|EMBL:EXX67492.1};	39.80	98	55	4	17	112	222	317	6e-09	63.5
rs:XP_003652281	hypothetical protein THITE_2113599 [Thielavia terrestris NRRL 8126].	39.33	89	52	2	24	112	207	293	6e-09	63.9
rs:XP_007784754	histidinol dehydrogenase [Coniosporium apollinis CBS 100218].	40.00	90	51	3	24	112	207	294	6e-09	63.5
tr:D3L6D0_9BACT	SubName: Full=Putative phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:EFD23408.1};	48.15	54	28	0	16	69	5	58	6e-09	58.9
rs:WP_017955710	hypothetical protein, partial [actinobacterium SCGC AAA278-O22].	54.00	50	23	0	14	63	8	57	7e-09	58.5
tr:L7J1T9_MAGOP	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:ELQ62191.1};	38.46	91	54	2	25	115	205	293	7e-09	63.5
rs:XP_003714233	histidine biosynthesis trifunctional protein [Magnaporthe oryzae 70-15].	38.46	91	54	2	25	115	205	293	7e-09	63.5
tr:A0A015L4R9_9GLOM	SubName: Full=Trifunctional histidinol dehydrogenase/phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase {ECO:0000313|EMBL:EXX67491.1};	39.80	98	55	4	17	112	222	317	7e-09	63.5
rs:XP_003659308	hypothetical protein MYCTH_2296153 [Myceliophthora thermophila ATCC 42464].	38.20	89	53	2	24	112	208	294	7e-09	63.5
tr:A0A0B7K5H5_BIOOC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CEO49871.1};	38.20	89	53	2	24	112	204	290	8e-09	63.5
gp:NEUHIS3_1	his-3 gene product [Neurospora crassa]	39.13	92	54	2	24	115	207	296	9e-09	63.2
rs:XP_007916914	putative histidine biosynthesis trifunctional protein [Togninia minima UCRPA7].	36.36	99	59	3	25	123	202	296	9e-09	63.2
rs:WP_034995300	phosphoribosyl-AMP cyclohydrolase, partial [Lactobacillus vini].	57.14	42	18	0	71	112	1	42	9e-09	58.2
tr:N1PT93_DOTSN	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EME46686.1};	40.00	90	51	3	24	112	214	301	1e-08	63.2
rs:XP_003667446	hypothetical protein NDAI_0A00450 [Naumovozyma dairenensis CBS 421].	35.35	99	58	3	24	117	143	240	1e-08	62.8
rs:XP_002497965	ZYRO0F17578p [Zygosaccharomyces rouxii].	36.96	92	54	2	24	112	152	242	1e-08	62.8
tr:A0A067QBZ2_9HOMO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDQ64593.1};	37.36	91	55	2	36	125	207	296	1e-08	62.8
tr:M3B4E1_SPHMS	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:EMF14667.1};	40.00	90	51	3	24	112	210	297	1e-08	62.8
tr:A0A084QNH8_9HYPO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFA65513.1};	38.64	88	52	2	25	112	205	290	1e-08	62.8
rs:XP_008714766	histidinol dehydrogenase [Cyphellophora europaea CBS 101466].	38.46	78	46	2	36	112	233	309	1e-08	62.8
tr:Q12201_PICPA	SubName: Full=HIS4 {ECO:0000313|EMBL:CAA86305.1};	36.67	90	54	3	24	112	198	285	1e-08	62.4
rs:XP_001908816	hypothetical protein [Podospora anserina S mat+].	38.20	89	53	2	24	112	207	293	1e-08	62.8
tr:A0A084AII8_STACH	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KEY65117.1};	38.64	88	52	2	25	112	205	290	2e-08	62.4
rs:XP_003675336	hypothetical protein NCAS_0B08820 [Naumovozyma castellii CBS 4309].	37.08	89	51	2	34	117	147	235	2e-08	62.0
rs:XP_007833705	Histidine biosynthesis trifunctional protein [Pestalotiopsis fici W106-1].	37.50	88	53	2	25	112	207	292	2e-08	62.4
tr:A0A084PU12_STACH	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFA53697.1};	38.64	88	52	2	25	112	205	290	2e-08	62.0
tr:W0VV37_ZYGBA	SubName: Full=Probable HIS4-Phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase/histidinol dehydrogenase {ECO:0000313|EMBL:CDH13306.1};	38.96	77	44	1	39	112	166	242	2e-08	62.0
tr:A0A074XNR1_AURPU	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:KEQ87130.1};	36.04	111	51	4	21	112	183	292	3e-08	61.6
rs:XP_007793769	putative histidine biosynthesis trifunctional protein [Eutypa lata UCREL1].	38.64	88	52	2	25	112	188	273	3e-08	61.6
rs:XP_002554272	KLTH0F01430p [Lachancea thermotolerans].	38.96	77	44	1	39	112	166	242	4e-08	61.2
rs:WP_023564389	phosphoribosyl-AMP cyclohydrolase [Escherichia coli].	39.06	64	33	1	2	65	1	58	5e-08	56.6
rs:WP_044379911	phosphoribosyl-ATP pyrophosphatase, partial [Escherichia coli].	45.28	53	29	0	60	112	1	53	5e-08	57.8
tr:A1BPP9_GEOCN	SubName: Full=HIS4 {ECO:0000313|EMBL:ABE73158.1}; EC=1.1.1.23 {ECO:0000313|EMBL:ABE73158.1}; EC=3.5.4.19 {ECO:0000313|EMBL:ABE73158.1}; EC=3.6.1.31 {ECO:0000313|EMBL:ABE73158.1};	36.67	90	54	3	24	112	198	285	5e-08	61.2
sp:HIS2_PICPA	RecName: Full=Histidine biosynthesis trifunctional protein; Includes: RecName: Full=Phosphoribosyl-AMP cyclohydrolase; EC=3.5.4.19; Includes: RecName: Full=Phosphoribosyl-ATP pyrophosphohydrolase; EC=3.6.1.31; Includes: RecName: Full=Histidinol dehydrogenase; Short=HDH; EC=1.1.1.23;	36.67	90	54	3	24	112	197	284	5e-08	60.8
rs:XP_003956824	hypothetical protein KAFR_0D00420 [Kazachstania africana CBS 2517].	38.10	84	47	2	39	117	146	229	5e-08	60.8
gp:AF027958_2	histidinol dehydrogenase [Expression vector pIB1]	36.67	90	54	3	24	112	198	285	5e-08	60.8
rs:XP_002490271	Multifunctional enzyme HIS4 [Komagataella pastoris GS115].	36.67	90	54	3	24	112	197	284	5e-08	60.8
gp:X56180_1	histidinol dehydrogenase [Komagataella pastoris]	36.67	90	54	3	24	112	198	285	5e-08	60.8
tr:F2QNA9_PICP7	SubName: Full=HIS4 protein {ECO:0000313|EMBL:CCA37064.1}; EC=1.1.1.23 {ECO:0000313|EMBL:CCA37064.1};	36.67	90	54	3	24	112	197	284	5e-08	60.8
tr:S6EMB8_ZYGB2	SubName: Full=ZYBA0S14-01816g1_1 {ECO:0000313|EMBL:CDF91817.1};	37.66	77	45	1	39	112	166	242	5e-08	60.8
tr:A0A074VI50_9PEZI	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:KEQ60178.1};	37.78	90	53	3	24	112	205	292	5e-08	60.8
tr:A0A074ZIN1_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KEQ98416.1};	38.89	90	52	3	24	112	205	292	6e-08	60.8
rs:XP_011271675	histidinol dehydrogenase [Wickerhamomyces ciferrii].	40.00	75	43	2	39	112	206	279	6e-08	60.5
tr:Q7ZA54_HEBCY	SubName: Full=HIS4 {ECO:0000313|EMBL:AAN08623.1};	36.67	90	54	3	24	112	192	279	7e-08	60.5
rs:XP_003644126	hypothetical protein Ecym_1051 [Eremothecium cymbalariae DBVPG#7215].	34.02	97	57	2	22	112	143	238	7e-08	60.5
rs:XP_007862434	histidine biosynthesis trifunctional-protein [Gloeophyllum trabeum ATCC 11539].	36.26	91	56	2	36	125	206	295	7e-08	60.5
tr:R9XBM7_ASHAC	SubName: Full=AaceriAFR703Wp {ECO:0000313|EMBL:AGO10812.1};	36.45	107	60	3	16	115	137	242	8e-08	60.5
rs:XP_012467274	PREDICTED: ferrochelatase-2, chloroplastic-like isoform X4 [Gossypium raimondii].	38.24	68	42	0	18	85	150	217	8e-08	58.5
tr:A0A068S852_9FUNG	SubName: Full=Histidine biosynthesis trifunctional-protein {ECO:0000313|EMBL:CDH57987.1};	42.67	75	41	2	39	112	219	292	8e-08	60.5
rs:XP_007315674	hypothetical protein SERLADRAFT_446819 [Serpula lacrymans var. lacrymans S7.9].	35.16	91	56	3	24	112	150	239	8e-08	60.1
tr:A0A093XL75_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFX93398.1}; Flags: Fragment;	39.33	89	51	3	25	112	197	283	1e-07	60.1
rs:XP_012467273	PREDICTED: ferrochelatase-2, chloroplastic-like isoform X3 [Gossypium raimondii].	38.24	68	42	0	18	85	191	258	1e-07	58.9
tr:A0A077WR17_9FUNG	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CDS09538.1};	42.67	75	41	2	39	112	219	292	1e-07	60.1
rs:XP_445010	hypothetical protein [Candida glabrata CBS 138].	33.00	100	62	3	17	112	139	237	1e-07	59.7
rs:XP_012467272	PREDICTED: ferrochelatase-1, chloroplastic-like isoform X2 [Gossypium raimondii].	38.24	68	42	0	18	85	200	267	1e-07	58.5
tr:X1B9C3_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_L05350 {ECO:0000313|EMBL:GAG80748.1}; Flags: Fragment;	57.69	52	13	3	81	123	1	52	1e-07	55.1
rs:XP_007391792	hypothetical protein PHACADRAFT_113598 [Phanerochaete carnosa HHB-10118-sp].	34.44	90	55	3	24	112	194	280	1e-07	59.7
rs:XP_001730231	hypothetical protein MGL_2613 [Malassezia globosa CBS 7966].	36.67	90	51	2	24	113	202	285	1e-07	59.7
tr:A0A094DM18_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY67476.1};	39.33	89	51	3	25	112	197	283	1e-07	59.7
tr:A0A094A240_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFX92076.1};	39.33	89	51	3	25	112	197	283	2e-07	59.7
rs:XP_776207	hypothetical protein CNBD0280 [Cryptococcus neoformans var. neoformans B-3501A].	32.98	94	60	3	24	115	188	280	2e-07	59.3
rs:XP_012049578	histidinol dehydrogenase [Cryptococcus neoformans var. grubii H99].	32.98	94	60	3	24	115	188	280	2e-07	59.3
tr:A0A094C8X1_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY50626.1};	39.33	89	51	3	25	112	197	283	2e-07	59.3
tr:A0A0D0YXF3_CRYGA	SubName: Full=Unplaced genomic scaffold supercont2.9, whole genome shotgun sequence {ECO:0000313|EMBL:KIR86170.1};	32.98	94	60	3	24	115	188	280	2e-07	59.3
tr:A0A0D0W6N9_CRYGA	SubName: Full=Unplaced genomic scaffold supercont1.8, whole genome shotgun sequence {ECO:0000313|EMBL:KIR54379.1};	32.98	94	60	3	24	115	188	280	2e-07	59.3
tr:A0A0D0VKZ7_CRYGA	SubName: Full=Unplaced genomic scaffold supercont1.9, whole genome shotgun sequence {ECO:0000313|EMBL:KIR47084.1};	32.98	94	60	3	24	115	188	280	2e-07	59.3
tr:A0A0D0WMN4_CRYGA	SubName: Full=Unplaced genomic scaffold supercont1.9, whole genome shotgun sequence {ECO:0000313|EMBL:KIR60306.1};	32.98	94	60	3	24	115	188	280	2e-07	59.3
rs:XP_003196025	histidinol dehydrogenase [Cryptococcus gattii WM276].	32.98	94	60	3	24	115	188	280	2e-07	59.3
rs:NP_986251	AFR703Wp [Ashbya gossypii ATCC 10895].	35.51	107	61	3	16	115	137	242	2e-07	59.3
rs:XP_012467271	PREDICTED: uncharacterized protein LOC105785697 isoform X1 [Gossypium raimondii].	35.71	84	50	1	18	101	210	289	2e-07	58.2
tr:A0A061ANU0_CYBFA	SubName: Full=CYFA0S03e01684g1_1 {ECO:0000313|EMBL:CDR39282.1};	38.89	90	52	3	24	112	185	272	2e-07	59.3
rs:WP_038328153	phosphoribosyl-AMP cyclohydrolase, partial [alpha proteobacterium SCGC AAA240-E13].	41.18	68	35	2	64	126	1	68	2e-07	55.1
tr:A0A0D0SKA2_CRYGA	SubName: Full=Unplaced genomic scaffold supercont2.9, whole genome shotgun sequence {ECO:0000313|EMBL:KIR33217.1};	32.97	91	58	3	24	112	188	277	2e-07	58.9
tr:A0A0D0T4X6_CRYGA	SubName: Full=Unplaced genomic scaffold supercont1.6, whole genome shotgun sequence {ECO:0000313|EMBL:KIR40907.1};	32.97	91	58	3	24	112	188	277	2e-07	58.9
tr:A0A093Z4A7_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY12166.1};	38.20	89	52	3	25	112	202	288	2e-07	58.9
rs:XP_003685892	hypothetical protein TPHA_0E03690 [Tetrapisispora phaffii CBS 4417].	48.33	60	24	1	60	112	189	248	3e-07	58.9
tr:W7UBD3_9STRA	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:EWM30304.1};	38.89	72	44	0	39	110	260	331	3e-07	57.8
rs:WP_016904404	hypothetical protein, partial [Xanthomonas arboricola].	50.00	46	23	0	69	114	1	46	3e-07	55.5
tr:A0A0D6EJM4_SPOSA	SubName: Full=SPOSA6832_01747-mRNA-1:cds {ECO:0000313|EMBL:CEQ40154.1}; Flags: Fragment;	34.57	81	46	2	39	112	233	313	3e-07	58.2
rs:XP_003680757	hypothetical protein TDEL_0C06570 [Torulaspora delbrueckii].	37.89	95	50	3	39	126	166	258	3e-07	58.5
tr:W6MF49_9ASCO	SubName: Full=Genomic scaffold, Kuraishia_capsulata_scaffold_1 {ECO:0000313|EMBL:CDK24269.1};	35.80	81	50	2	33	112	196	275	3e-07	58.5
rs:WP_019183000	hypothetical protein, partial [Stenotrophomonas maltophilia].	47.92	48	25	0	24	71	23	70	4e-07	53.9
tr:A0A0C3NZ40_PHLGI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIP10714.1};	37.33	75	45	2	39	112	207	280	4e-07	58.2
tr:A0A094DGF1_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY33892.1};	37.08	89	53	3	25	112	202	288	6e-07	57.8
tr:A0A024GPX6_9STRA	SubName: Full=Albugo candida WGS project CAIX00000000 data, strain Ac Nc2, contig AcNc2_CONTIG_238_length_39925 {ECO:0000313|EMBL:CCI48611.1};	36.67	90	55	2	24	112	236	324	1e-06	56.2
tr:A0A0B7N5T0_9FUNG	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CEP10394.1};	38.46	78	46	2	36	112	204	280	1e-06	56.6
tr:M7X6U2_RHOT1	SubName: Full=Phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:EMS26086.1};	35.80	81	45	2	39	112	234	314	1e-06	56.2
tr:J8V185_PSEPU	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	55.81	43	18	1	78	119	1	43	2e-06	52.4
tr:K2D4A4_9BACT	RecName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|SAAS:SAAS00103216}; EC=3.5.4.19 {ECO:0000256|SAAS:SAAS00103216};	32.73	110	66	3	21	123	271	379	2e-06	55.8
tr:A0A0C7NF19_9SACH	SubName: Full=LALA0S11e01178g1_1 {ECO:0000313|EMBL:CEP64308.1};	36.36	77	46	1	39	112	166	242	2e-06	55.8
tr:X1SGQ2_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_S07416 {ECO:0000313|EMBL:GAI92197.1}; Flags: Fragment;	58.33	36	15	0	83	118	2	37	2e-06	53.1
tr:A0A075I9N7_9ARCH	SubName: Full=Phosphoribosyl-AMP cyclohydrolase (HisIE) {ECO:0000313|EMBL:AIF22838.1}; EC=3.5.4.19 {ECO:0000313|EMBL:AIF22838.1};	42.22	45	26	0	70	114	1	45	3e-06	51.2
tr:S2J4L3_MUCC1	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:EPB83052.1};	38.96	77	45	2	37	112	205	280	3e-06	55.8
tr:A0A0C9LS36_9FUNG	SubName: Full=DNA, scaffold: scf_mam1_v10023, strain NBRC 6742, whole genome shotgun sequence {ECO:0000313|EMBL:GAN02520.1};	38.96	77	45	2	37	112	207	282	3e-06	55.5
tr:A0A0A1N5N1_9FUNG	SubName: Full=Putative Histidine biosynthesis trifunctional-protein {ECO:0000313|EMBL:CEI87113.1};	33.33	111	60	4	14	112	172	280	3e-06	55.5
tr:A0A075G8S5_9ARCH	SubName: Full=Phosphoribosyl-AMP cyclohydrolase (HisIE) {ECO:0000313|EMBL:AIF00406.1}; EC=3.5.4.19 {ECO:0000313|EMBL:AIF00406.1};	44.44	45	25	0	70	114	1	45	4e-06	50.8
tr:A0A0C7C9H8_9FUNG	SubName: Full=RMATCC62417_14588 protein {ECO:0000313|EMBL:CEG80220.1};	36.71	79	48	2	35	112	6	83	4e-06	54.7
tr:A0A066VUJ8_9BASI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDN43943.1};	34.88	129	70	7	5	123	204	328	5e-06	55.1
tr:A0A0C7CA30_9FUNG	SubName: Full=RMATCC62417_14588 protein {ECO:0000313|EMBL:CEG80219.1};	36.71	79	48	2	35	112	6	83	5e-06	54.7
tr:I1BTA7_RHIO9	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EIE79437.1};	35.35	99	60	4	16	112	183	279	5e-06	54.7
tr:S3BZT0_OPHP1	SubName: Full=Histidine biosynthesis trifunctional protein {ECO:0000313|EMBL:EPE06032.1};	35.96	89	54	3	25	112	211	297	6e-06	54.7
tr:D3L6D1_9BACT	SubName: Full=Phosphoribosyl-AMP cyclohydrolase {ECO:0000313|EMBL:EFD23409.1}; EC=3.5.4.19 {ECO:0000313|EMBL:EFD23409.1}; Flags: Fragment;	56.76	37	16	0	83	119	5	41	8e-06	50.1
rs:WP_036527427	phosphoribosyl-AMP cyclohydrolase, partial [Nitrosococcus oceani].	53.66	41	19	0	16	56	7	47	9e-06	49.7
rs:XP_004993723	hisD [Salpingoeca rosetta].	36.36	77	47	2	37	112	216	291	1e-05	53.9
tr:U7PLZ0_SPOS1	SubName: Full=Histidinol dehydrogenase {ECO:0000313|EMBL:ERS96668.1};	35.96	89	54	3	25	112	219	305	1e-05	53.9